# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- ACT_5 PF13710.1 EIW73719.1 - 0.0054 16.5 0.9 1.2 8.9 0.0 2.4 2 1 1 3 3 3 2 ACT domain Transposase_21 PF02992.9 EIW73721.1 - 0.045 12.8 0.0 0.045 12.8 0.0 2.4 3 0 0 3 3 3 0 Transposase family tnp2 UBN2_3 PF14244.1 EIW73724.1 - 0.00027 20.5 0.0 0.00032 20.2 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EIW73724.1 - 0.012 15.2 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIW73724.1 - 0.098 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type SNF5 PF04855.7 EIW73726.1 - 0.00049 19.6 0.0 0.00098 18.6 0.0 1.3 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 DUF2798 PF11391.3 EIW73726.1 - 0.012 15.3 2.3 0.019 14.7 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) Sin3_corepress PF08295.7 EIW73727.1 - 0.14 11.8 0.0 0.38 10.5 0.0 1.6 1 0 0 1 1 1 0 Sin3 family co-repressor AAA PF00004.24 EIW73732.1 - 1.6e-14 54.2 0.0 1.8e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RseC_MucC PF04246.7 EIW73733.1 - 0.0085 15.6 0.0 0.018 14.5 0.0 1.5 1 0 0 1 1 1 1 Positive regulator of sigma(E), RseC/MucC Retrotrans_gag PF03732.12 EIW73734.1 - 7.7e-10 38.7 0.0 1.7e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein WES_acyltransf PF03007.11 EIW73734.1 - 0.042 13.4 4.0 0.11 12.0 2.7 1.6 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain RVP_2 PF08284.6 EIW73735.1 - 7.8e-06 25.8 0.0 7.8e-06 25.8 0.0 1.0 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIW73735.1 - 0.00045 20.6 0.0 0.00045 20.6 0.0 1.0 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIW73735.1 - 0.0082 15.9 0.0 0.0088 15.8 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease DUF1198 PF06711.6 EIW73737.1 - 0.075 12.8 0.0 0.096 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1198) UBN2_2 PF14227.1 EIW73738.1 - 0.00046 19.7 0.0 0.00078 18.9 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF605 PF04652.11 EIW73738.1 - 0.0093 15.3 21.4 0.012 14.9 14.8 1.2 1 0 0 1 1 1 1 Vta1 like DUF2011 PF09428.5 EIW73738.1 - 0.47 10.3 12.9 0.022 14.6 5.0 1.6 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF2011) Suf PF05843.9 EIW73738.1 - 1.1 8.8 11.2 2.1 8.0 7.8 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DDHD PF02862.12 EIW73738.1 - 1.4 8.6 9.2 2.7 7.7 6.4 1.4 1 0 0 1 1 1 0 DDHD domain Neur_chan_memb PF02932.11 EIW73738.1 - 3.1 7.6 5.1 5.1 6.9 3.5 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RVT_2 PF07727.9 EIW73739.1 - 8.1e-38 129.7 0.2 8.8e-38 129.6 0.1 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVP_2 PF08284.6 EIW73744.1 - 1.3e-09 38.0 0.0 1.6e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EIW73744.1 - 0.00041 20.8 0.0 0.00052 20.4 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease Retrotrans_gag PF03732.12 EIW73745.1 - 6.9e-12 45.2 0.1 1.1e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_4 PF14392.1 EIW73745.1 - 1.7 8.3 5.9 3 7.5 0.6 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 EIW73745.1 - 3.9 7.5 9.8 0.17 11.9 1.0 2.3 2 0 0 2 2 2 0 Zinc knuckle Lamp PF01299.12 EIW73746.1 - 6.6 5.7 12.8 10 5.1 8.9 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) F-box-like PF12937.2 EIW73751.1 - 0.0047 16.6 0.2 0.0083 15.8 0.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW73751.1 - 0.079 12.6 0.1 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 F-box domain Penicillinase_R PF03965.11 EIW73752.1 - 0.053 13.6 0.1 0.072 13.1 0.0 1.3 1 1 0 1 1 1 0 Penicillinase repressor Zip PF02535.17 EIW73753.1 - 0.062 12.3 0.4 0.093 11.7 0.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF605 PF04652.11 EIW73753.1 - 0.37 10.1 29.0 0.69 9.2 20.1 1.5 1 0 0 1 1 1 0 Vta1 like Hid1 PF12722.2 EIW73753.1 - 0.95 7.0 4.8 1.3 6.6 3.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.11 EIW73753.1 - 1.1 9.1 5.3 1.9 8.3 3.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.9 EIW73753.1 - 1.1 8.8 11.6 2 8.0 8.1 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Rtf2 PF04641.7 EIW73753.1 - 2.3 7.3 12.9 3.7 6.6 8.9 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger DDHD PF02862.12 EIW73753.1 - 5.8 6.6 10.7 11 5.6 7.4 1.4 1 0 0 1 1 1 0 DDHD domain RR_TM4-6 PF06459.7 EIW73753.1 - 7.9 6.2 9.8 15 5.3 6.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4551 PF15087.1 EIW73753.1 - 9.4 4.4 8.5 13 3.9 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CytochromB561_N PF09786.4 EIW73753.1 - 9.9 4.4 11.6 15 3.8 8.0 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF4413 PF14372.1 EIW73754.1 - 2.7e-05 24.0 0.3 3.1e-05 23.8 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4413) Dimer_Tnp_hAT PF05699.9 EIW73755.1 - 1.3e-09 37.5 0.1 1.7e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ZZ PF00569.12 EIW73759.1 - 0.043 13.3 5.5 0.18 11.3 3.8 2.1 1 0 0 1 1 1 0 Zinc finger, ZZ type zf-B_box PF00643.19 EIW73759.1 - 1.6 8.6 10.9 0.043 13.7 2.1 2.5 3 0 0 3 3 3 0 B-box zinc finger Zip PF02535.17 EIW73760.1 - 0.11 11.4 0.3 0.18 10.8 0.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 EIW73760.1 - 1.2 9.0 5.5 2.2 8.1 3.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 EIW73760.1 - 4.9 4.6 6.8 6.7 4.2 4.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Retrotrans_gag PF03732.12 EIW73762.1 - 0.088 12.8 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC PF00098.18 EIW73762.1 - 0.12 12.3 3.3 0.42 10.6 2.3 1.9 1 1 0 1 1 1 0 Zinc knuckle gag-asp_proteas PF13975.1 EIW73763.1 - 7.8e-05 22.4 0.0 8.2e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EIW73763.1 - 0.0014 19.0 0.0 0.0014 19.0 0.0 1.0 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EIW73763.1 - 0.076 12.9 0.0 0.086 12.7 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease E_raikovi_mat PF06360.6 EIW73764.1 - 0.042 14.0 1.6 0.14 12.3 1.1 1.9 1 0 0 1 1 1 0 Euplotes raikovi mating pheromone DEAD PF00270.24 EIW73765.1 - 1.2e-10 41.2 0.0 1.8e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EIW73765.1 - 0.057 13.2 0.2 0.12 12.2 0.1 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Retrotrans_gag PF03732.12 EIW73766.1 - 1.2e-11 44.4 0.0 2e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_4 PF14392.1 EIW73766.1 - 1.7 8.3 5.9 3 7.5 0.6 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 EIW73766.1 - 3.9 7.5 9.8 0.17 11.9 1.0 2.3 2 0 0 2 2 2 0 Zinc knuckle DUF262 PF03235.9 EIW73771.1 - 1.1e-16 61.5 0.6 2.7e-16 60.2 0.4 1.6 1 1 0 1 1 1 1 Protein of unknown function DUF262 zf-C2HC_2 PF13913.1 EIW73773.1 - 0.15 11.7 0.3 0.15 11.7 0.2 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type KOW PF00467.24 EIW73775.1 - 0.011 15.3 0.6 0.06 13.0 0.4 2.2 2 0 0 2 2 2 0 KOW motif Dimer_Tnp_hAT PF05699.9 EIW73777.1 - 3e-15 55.5 0.3 3.3e-15 55.4 0.2 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Erythro-docking PF09277.6 EIW73779.1 - 0.13 11.9 3.5 0.73 9.5 0.2 2.5 2 0 0 2 2 2 0 Erythronolide synthase, docking Crl PF07417.7 EIW73780.1 - 0.002 17.8 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Transcriptional regulator Crl ZZ PF00569.12 EIW73782.1 - 0.062 12.8 5.5 0.26 10.8 3.8 2.0 1 0 0 1 1 1 0 Zinc finger, ZZ type zf-B_box PF00643.19 EIW73782.1 - 3 7.8 10.7 0.076 12.9 2.0 2.5 3 0 0 3 3 3 0 B-box zinc finger FAD_binding_4 PF01565.18 EIW73783.1 - 5.5e-09 35.6 2.3 1.3e-08 34.4 1.6 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EIW73783.1 - 3.4e-08 33.2 1.0 8.4e-08 31.9 0.2 2.1 2 0 0 2 2 2 1 Berberine and berberine like FAD_binding_4 PF01565.18 EIW73784.1 - 0.035 13.5 0.0 0.068 12.6 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain zf-CCHC PF00098.18 EIW73787.1 - 0.00028 20.6 3.7 0.00028 20.6 2.5 2.9 3 0 0 3 3 3 1 Zinc knuckle RVT_thumb PF06817.9 EIW73791.1 - 0.0084 15.6 0.0 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 Reverse transcriptase thumb domain RVT_3 PF13456.1 EIW73792.1 - 5e-05 23.0 0.0 7.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase-like Phage_integrase PF00589.17 EIW73793.1 - 0.0044 16.7 0.0 0.064 12.9 0.0 2.4 3 0 0 3 3 3 1 Phage integrase family DUF605 PF04652.11 EIW73794.1 - 0.56 9.5 9.3 0.67 9.2 6.4 1.1 1 0 0 1 1 1 0 Vta1 like UBN2_2 PF14227.1 EIW73795.1 - 7.5e-07 28.7 0.0 1.4e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIW73795.1 - 0.00011 22.0 0.0 0.00017 21.3 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EIW73795.1 - 0.079 12.5 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4159 PF13709.1 EIW73800.1 - 0.055 12.5 0.0 0.059 12.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4159) Tet_JBP PF12851.2 EIW73804.1 - 6.5e-11 41.8 0.0 7.1e-11 41.7 0.0 1.0 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily CDC45 PF02724.9 EIW73806.1 - 0.35 8.8 4.4 0.4 8.6 3.0 1.0 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 EIW73806.1 - 2.2 7.4 6.3 2.3 7.4 4.4 1.0 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 EIW73806.1 - 9.4 4.8 11.2 9.4 4.8 7.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DDE_1 PF03184.14 EIW73807.1 - 0.00091 18.4 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Retrotrans_gag PF03732.12 EIW73808.1 - 0.054 13.5 0.1 1.1 9.4 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein DUF3450 PF11932.3 EIW73808.1 - 0.067 12.4 3.9 0.13 11.5 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-CCHC PF00098.18 EIW73808.1 - 2.4 8.2 7.3 0.59 10.1 2.2 2.2 2 1 0 2 2 2 0 Zinc knuckle gag-asp_proteas PF13975.1 EIW73809.1 - 7.8e-05 22.4 0.0 8.2e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EIW73809.1 - 0.0014 19.0 0.0 0.0014 19.0 0.0 1.0 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.6 EIW73809.1 - 0.076 12.9 0.0 0.086 12.7 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease Pkinase PF00069.20 EIW73818.1 - 1.2e-11 44.2 0.2 5.2e-08 32.3 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW73818.1 - 9.6e-10 37.9 0.1 1.6e-07 30.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EIW73819.1 - 4.9e-07 29.1 0.0 0.018 14.1 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW73819.1 - 6.4e-07 28.6 0.0 0.0014 17.8 0.1 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Acid_PPase PF12689.2 EIW73820.1 - 1.7e-12 47.3 0.2 2.2e-12 46.9 0.1 1.1 1 0 0 1 1 1 1 Acid Phosphatase DUF605 PF04652.11 EIW73821.1 - 2.3 7.5 12.9 3.1 7.1 9.0 1.2 1 0 0 1 1 1 0 Vta1 like IIGP PF05049.8 EIW73822.1 - 0.0029 16.5 0.1 0.0051 15.6 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 EIW73822.1 - 0.0059 16.1 0.0 0.014 14.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EIW73822.1 - 0.032 14.5 3.4 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_17 PF13207.1 EIW73822.1 - 0.057 14.2 3.4 0.56 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EIW73822.1 - 0.065 13.1 0.1 0.19 11.6 0.1 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.13 EIW73822.1 - 0.18 11.3 0.7 0.32 10.4 0.1 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EIW73822.1 - 0.18 11.7 0.1 0.18 11.7 0.1 2.3 1 1 1 2 2 1 0 AAA ATPase domain Miro PF08477.8 EIW73822.1 - 0.29 11.6 1.0 0.67 10.4 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein DUF87 PF01935.12 EIW73822.1 - 0.43 10.3 0.2 0.43 10.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_10 PF12846.2 EIW73822.1 - 0.47 9.8 0.1 0.47 9.8 0.1 2.1 2 1 1 3 3 3 0 AAA-like domain AAA_22 PF13401.1 EIW73822.1 - 0.49 10.5 0.1 0.49 10.5 0.0 2.1 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EIW73822.1 - 0.72 9.6 0.1 0.72 9.6 0.1 2.4 2 1 0 2 2 2 0 Dynamin family AAA_23 PF13476.1 EIW73822.1 - 0.85 9.9 0.0 0.85 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Borrelia_P83 PF05262.6 EIW73822.1 - 1.1 7.4 22.2 1.2 7.2 15.4 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Cytadhesin_P30 PF07271.6 EIW73822.1 - 2.2 7.4 5.2 2.6 7.2 3.6 1.1 1 0 0 1 1 1 0 Cytadhesin P30/P32 Asp-B-Hydro_N PF05279.6 EIW73822.1 - 4.3 7.1 16.2 5.1 6.8 11.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF3807 PF12720.2 EIW73822.1 - 5.8 7.0 14.0 8 6.5 9.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Retrotrans_gag PF03732.12 EIW73823.1 - 0.00026 20.9 0.4 0.0006 19.8 0.3 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EIW73823.1 - 0.027 14.3 2.3 0.043 13.7 1.6 1.3 1 0 0 1 1 1 0 Zinc knuckle DDE_3 PF13358.1 EIW73824.1 - 6.5e-13 48.6 0.1 8.3e-08 32.0 0.0 2.3 2 0 0 2 2 2 2 DDE superfamily endonuclease DUF2730 PF10805.3 EIW73827.1 - 0.012 15.3 0.1 0.031 13.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) TBPIP PF07106.8 EIW73827.1 - 0.016 14.7 0.0 0.016 14.7 0.0 1.5 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF793 PF05633.6 EIW73827.1 - 1.3 7.6 4.4 0.26 9.9 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF793) Tet_JBP PF12851.2 EIW73828.1 - 1.1e-12 47.5 0.0 1.4e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily UBN2 PF14223.1 EIW73829.1 - 0.0057 16.4 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EIW73829.1 - 0.032 13.7 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF1465 PF07323.7 EIW73829.1 - 0.034 13.7 0.1 0.084 12.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1465) zf-RVT PF13966.1 EIW73830.1 - 0.0055 16.9 0.1 0.0085 16.3 0.1 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase BCS1_N PF08740.6 EIW73831.1 - 1.1e-27 96.8 1.2 1.5e-27 96.4 0.9 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EIW73831.1 - 0.00016 21.8 0.0 0.00026 21.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EIW73831.1 - 0.0072 15.4 0.0 0.011 14.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 EIW73831.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 EIW73831.1 - 0.017 14.7 0.1 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EIW73831.1 - 0.03 13.3 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EIW73831.1 - 0.035 14.9 0.3 0.098 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EIW73831.1 - 0.066 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIW73831.1 - 0.082 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EIW73831.1 - 0.095 12.2 0.0 0.22 11.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 EIW73831.1 - 0.14 12.6 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein DUF659 PF04937.10 EIW73832.1 - 2e-07 30.6 0.0 4.6e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.9 EIW73832.1 - 2.7e-05 23.7 0.0 7.4e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region BAG PF02179.11 EIW73832.1 - 0.14 12.3 4.5 3 8.0 0.0 3.6 3 0 0 3 3 3 0 BAG domain DUF3678 PF12435.3 EIW73833.1 - 1.2 8.8 5.3 5.6 6.6 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3678) DEAD PF00270.24 EIW73836.1 - 0.016 14.6 0.0 0.019 14.4 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase T2SE PF00437.15 EIW73836.1 - 0.082 11.7 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF258 PF03193.11 EIW73836.1 - 0.088 11.9 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EIW73836.1 - 0.097 12.3 0.0 0.18 11.4 0.0 1.4 2 0 0 2 2 2 0 Archaeal ATPase NACHT PF05729.7 EIW73836.1 - 0.16 11.6 0.1 0.34 10.5 0.0 1.5 2 0 0 2 2 2 0 NACHT domain DUF4218 PF13960.1 EIW73840.1 - 0.0021 17.4 0.3 0.0055 16.1 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) Transposase_21 PF02992.9 EIW73840.1 - 0.0072 15.4 1.1 0.017 14.1 0.1 1.9 2 0 0 2 2 2 1 Transposase family tnp2 Transposase_21 PF02992.9 EIW73842.1 - 0.0001 21.5 0.0 0.00025 20.2 0.0 1.6 2 0 0 2 2 2 1 Transposase family tnp2 Dimer_Tnp_hAT PF05699.9 EIW73844.1 - 1.5e-09 37.3 0.1 1.7e-09 37.1 0.1 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region F-box-like PF12937.2 EIW73847.1 - 1.8e-08 33.9 0.6 3.4e-07 29.8 0.5 2.9 2 1 1 3 3 3 1 F-box-like LRR_8 PF13855.1 EIW73847.1 - 0.048 13.4 0.2 9.9 6.0 0.0 3.3 1 1 0 2 2 2 0 Leucine rich repeat zf-CCHC_4 PF14392.1 EIW73852.1 - 0.28 10.8 8.3 0.54 9.9 1.5 2.5 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 EIW73852.1 - 0.32 11.0 11.5 0.28 11.1 0.9 2.4 2 0 0 2 2 2 0 Zinc knuckle Helicase_C PF00271.26 EIW73853.1 - 2.3e-08 33.7 0.1 4.6e-08 32.8 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain MFS_1 PF07690.11 EIW73854.1 - 8.9e-31 106.8 28.2 8.9e-31 106.8 19.6 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MMPL PF03176.10 EIW73854.1 - 0.7 8.5 3.8 0.83 8.3 1.8 1.6 2 0 0 2 2 2 0 MMPL family Pkinase PF00069.20 EIW73856.1 - 2.2e-30 105.6 0.0 4.6e-16 58.7 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW73856.1 - 1.2e-25 90.0 0.0 2.4e-24 85.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Transposase_21 PF02992.9 EIW73857.1 - 1.5e-09 37.2 0.0 3.3e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EIW73857.1 - 0.00023 20.6 0.0 0.00043 19.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) CAF-1_p150 PF11600.3 EIW73858.1 - 0.035 13.4 8.0 0.045 13.1 5.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Adeno_terminal PF02459.10 EIW73858.1 - 0.041 12.0 2.5 0.041 12.0 1.7 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein SOBP PF15279.1 EIW73858.1 - 0.043 14.1 1.6 0.046 14.0 1.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2146 PF10220.4 EIW73858.1 - 1.7 6.5 6.0 2.1 6.2 4.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Transposase_21 PF02992.9 EIW73862.1 - 5.1e-10 38.8 0.0 1.2e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EIW73862.1 - 0.0064 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF1798 PF08807.5 EIW73864.1 - 0.004 16.8 1.2 0.0054 16.4 0.8 1.2 1 0 0 1 1 1 1 Bacterial domain of unknown function (DUF1798) Angiomotin_C PF12240.3 EIW73864.1 - 0.0043 16.5 0.2 0.0053 16.2 0.1 1.2 1 0 0 1 1 1 1 Angiomotin C terminal Fmp27_WPPW PF10359.4 EIW73864.1 - 0.018 13.4 0.5 0.022 13.2 0.4 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Peptidase_C14 PF00656.17 EIW73865.1 - 7.3e-32 111.0 0.0 9e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Orbi_VP4 PF05059.7 EIW73865.1 - 0.03 12.0 0.0 0.044 11.5 0.0 1.2 1 0 0 1 1 1 0 Orbivirus VP4 core protein DUF2600 PF10776.4 EIW73865.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) F-box-like PF12937.2 EIW73866.1 - 1.3e-08 34.4 2.4 1.7e-08 34.0 0.1 2.1 2 0 0 2 2 2 1 F-box-like Retrotrans_gag PF03732.12 EIW73870.1 - 3.4e-11 43.0 0.1 6e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC_4 PF14392.1 EIW73870.1 - 3.1 7.5 5.9 4.1 7.1 0.6 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 EIW73870.1 - 7.1 6.7 9.8 0.23 11.4 1.0 2.3 2 0 0 2 2 2 0 Zinc knuckle TraH_2 PF06871.6 EIW73874.1 - 8.6 5.7 9.9 0.69 9.3 0.1 2.4 2 0 0 2 2 2 0 TraH_2 DisA_N PF02457.11 EIW73875.1 - 0.15 11.2 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding PEP-utilisers_N PF05524.8 EIW73884.1 - 0.018 14.8 0.0 0.05 13.4 0.0 1.7 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal HMG_box PF00505.14 EIW73884.1 - 0.17 12.1 3.9 0.17 12.1 0.2 2.4 2 0 0 2 2 2 0 HMG (high mobility group) box HMG_box_2 PF09011.5 EIW73884.1 - 0.66 10.3 8.0 0.39 11.1 0.4 2.8 3 0 0 3 3 3 0 HMG-box domain PgpA PF04608.8 EIW73885.1 - 0.061 13.1 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylglycerophosphatase A p450 PF00067.17 EIW73889.1 - 1e-26 93.5 0.0 1.1e-26 93.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TC1 PF15063.1 EIW73891.1 - 0.35 10.4 2.5 0.51 9.9 0.1 2.2 2 0 0 2 2 2 0 Thyroid cancer protein 1 FAD_binding_4 PF01565.18 EIW73893.1 - 0.00016 21.1 0.1 0.0003 20.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Herpes_capsid PF06112.6 EIW73897.1 - 0.17 11.9 4.9 0.29 11.1 3.4 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Spc24 PF08286.6 EIW73898.1 - 0.18 11.4 0.0 0.4 10.3 0.0 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Ndc1_Nup PF09531.5 EIW73898.1 - 6.6 5.0 4.8 9.4 4.5 3.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-B_box PF00643.19 EIW73901.1 - 0.47 10.3 4.6 1.6 8.6 3.2 2.0 1 0 0 1 1 1 0 B-box zinc finger Tet_JBP PF12851.2 EIW73902.1 - 1.3e-08 34.2 0.0 1.7e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily CENP-B_dimeris PF09026.5 EIW73903.1 - 7.1 6.9 9.3 0.27 11.4 2.0 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CobW_C PF07683.9 EIW73907.1 - 0.038 13.7 0.3 1.2 8.9 0.0 2.6 2 0 0 2 2 2 0 Cobalamin synthesis protein cobW C-terminal domain RHH_1 PF01402.16 EIW73911.1 - 0.17 11.7 1.2 7.9 6.5 0.0 3.5 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family SNF2_N PF00176.18 EIW73914.1 - 4.8e-25 87.9 0.1 5.4e-25 87.7 0.1 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain LEF-8 PF04941.7 EIW73914.1 - 0.005 14.5 0.1 0.0056 14.4 0.1 1.0 1 0 0 1 1 1 1 Late expression factor 8 (LEF-8) ResIII PF04851.10 EIW73914.1 - 0.0057 16.5 0.0 0.0062 16.3 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_14 PF13173.1 EIW73914.1 - 0.09 12.6 0.0 0.091 12.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EIW73914.1 - 0.13 12.4 0.0 0.14 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain HSBP1 PF06825.7 EIW73918.1 - 0.012 15.2 2.7 0.044 13.3 0.5 2.3 2 0 0 2 2 2 0 Heat shock factor binding protein 1 Uds1 PF15456.1 EIW73918.1 - 0.028 14.4 13.4 0.023 14.6 3.9 2.9 2 1 1 3 3 3 0 Up-regulated During Septation V_ATPase_I PF01496.14 EIW73918.1 - 0.13 10.1 1.9 0.16 9.7 1.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cep57_MT_bd PF06657.8 EIW73918.1 - 0.16 11.9 2.1 18 5.3 0.1 3.1 3 0 0 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Exonuc_VII_L PF02601.10 EIW73918.1 - 0.16 11.1 3.9 0.23 10.6 2.7 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Mnd1 PF03962.10 EIW73918.1 - 0.21 11.2 3.3 0.17 11.4 0.4 1.9 1 1 1 2 2 2 0 Mnd1 family PspB PF06667.7 EIW73918.1 - 0.74 9.7 3.0 10 6.1 0.2 2.6 1 1 1 2 2 2 0 Phage shock protein B DUF4510 PF14971.1 EIW73918.1 - 1.5 8.9 5.8 8.8 6.4 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4510) Tet_JBP PF12851.2 EIW73919.1 - 6.6e-13 48.3 0.0 8e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily 2OG-FeII_Oxy_3 PF13640.1 EIW73919.1 - 0.0035 17.8 0.0 0.0062 17.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PBP1_TM PF14812.1 EIW73920.1 - 0.46 10.8 4.3 0.92 9.8 3.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Zn_clus PF00172.13 EIW73920.1 - 0.68 9.8 8.6 1.6 8.7 5.9 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MSP1_C PF07462.6 EIW73922.1 - 1.9 6.8 13.3 1.4 7.2 1.1 2.3 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus DUF1767 PF08585.7 EIW73926.1 - 0.1 12.9 0.5 1.3 9.3 0.0 2.8 4 0 0 4 4 4 0 Domain of unknown function (DUF1767) EST1_DNA_bind PF10373.4 EIW73927.1 - 1.1e-05 24.7 0.1 0.019 14.1 0.0 2.5 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain CobT PF06213.7 EIW73929.1 - 0.56 9.3 8.5 0.59 9.2 5.9 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 EIW73929.1 - 0.65 7.9 3.0 0.72 7.8 2.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.8 EIW73929.1 - 3.6 5.2 10.8 4.1 5.0 7.5 1.0 1 0 0 1 1 1 0 DNA polymerase phi ORC6 PF05460.8 EIW73934.1 - 2.9 6.8 7.8 3.4 6.6 5.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) WD40 PF00400.27 EIW73936.1 - 3e-46 153.7 20.5 5.4e-08 32.4 0.0 9.5 10 0 0 10 10 10 8 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW73936.1 - 2.4e-05 23.8 0.8 0.018 14.5 0.0 3.6 2 2 0 3 3 3 1 PQQ-like domain PD40 PF07676.7 EIW73936.1 - 5.2e-05 22.8 2.4 23 4.8 0.0 7.4 8 0 0 8 8 8 1 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EIW73936.1 - 0.00015 20.1 0.2 0.58 8.2 0.0 3.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Gmad1 PF10647.4 EIW73936.1 - 0.00036 19.9 0.0 0.0024 17.2 0.0 2.3 1 1 1 2 2 2 1 Lipoprotein LpqB beta-propeller domain Nbas_N PF15492.1 EIW73936.1 - 0.00044 19.4 1.3 3.9 6.4 0.0 4.9 4 2 1 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Penicillinase_R PF03965.11 EIW73937.1 - 0.053 13.6 0.1 0.072 13.1 0.0 1.3 1 1 0 1 1 1 0 Penicillinase repressor DUF659 PF04937.10 EIW73939.1 - 1.5e-05 24.4 0.2 3e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Helicase_C PF00271.26 EIW73940.1 - 2.2e-14 53.0 0.0 5.9e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIW73940.1 - 1.8e-05 24.2 0.0 2.9e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EIW73940.1 - 0.071 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit FeThRed_B PF02943.10 EIW73943.1 - 0.067 12.9 4.9 0.092 12.4 3.4 1.2 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase catalytic beta chain Sdh5 PF03937.11 EIW73944.1 - 0.064 12.9 0.0 0.086 12.5 0.0 1.2 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase DUF3274 PF11678.3 EIW73945.1 - 0.026 13.7 0.0 0.035 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3274) Dimer_Tnp_hAT PF05699.9 EIW73948.1 - 3.5e-10 39.3 0.2 3.9e-10 39.1 0.2 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region F-box-like PF12937.2 EIW73949.1 - 1.1e-07 31.4 0.5 3.6e-07 29.7 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW73949.1 - 0.017 14.7 0.2 0.077 12.6 0.1 2.2 1 0 0 1 1 1 0 F-box domain Prenyltrans PF00432.16 EIW73953.1 - 2.9e-60 199.4 6.3 3.2e-13 49.0 0.1 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EIW73953.1 - 3.2e-34 117.7 0.0 1.5e-15 57.6 0.0 4.0 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EIW73953.1 - 3.9e-09 36.4 0.0 2.5e-05 24.2 0.0 3.2 1 1 2 3 3 3 3 Prenyltransferase-like RAP1 PF07218.6 EIW73954.1 - 0.26 9.3 0.1 0.34 8.9 0.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Rad60-SLD PF11976.3 EIW73957.1 - 1.4e-23 82.3 0.3 1.8e-23 81.9 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EIW73957.1 - 6.8e-10 38.2 0.1 9.2e-10 37.7 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family Cadherin-like PF12733.2 EIW73957.1 - 0.029 14.6 2.1 0.42 10.9 1.5 2.5 1 1 0 1 1 1 0 Cadherin-like beta sandwich domain 2OG-FeII_Oxy_2 PF13532.1 EIW73959.1 - 3.8e-25 88.8 0.0 4.6e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TMEM154 PF15102.1 EIW73960.1 - 0.0078 15.9 1.8 0.0099 15.5 0.0 2.0 2 0 0 2 2 2 1 TMEM154 protein family Herpes_gE PF02480.11 EIW73960.1 - 0.039 12.2 0.0 0.064 11.5 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF202 PF02656.10 EIW73960.1 - 0.076 13.2 0.1 0.2 11.9 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Beta-APP PF03494.8 EIW73960.1 - 0.48 9.9 2.6 1.1 8.7 1.8 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) FAD_binding_4 PF01565.18 EIW73961.1 - 1.7e-19 69.6 1.6 1.7e-19 69.6 1.1 1.5 2 0 0 2 2 2 1 FAD binding domain FAD_binding_4 PF01565.18 EIW73963.1 - 2.6e-10 39.9 4.0 5.9e-10 38.7 2.8 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EIW73963.1 - 6.7e-09 35.5 0.5 1.3e-08 34.5 0.1 1.8 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 EIW73963.1 - 0.15 11.1 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF455 PF04305.9 EIW73964.1 - 7.4e-87 290.8 0.0 9.8e-87 290.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF455) Rieske PF00355.21 EIW73964.1 - 2.5e-08 33.3 0.1 5e-08 32.3 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.1 EIW73964.1 - 0.00032 20.3 0.0 0.00073 19.2 0.0 1.5 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain TauD PF02668.11 EIW73965.1 - 2.6e-47 161.6 0.1 3.5e-47 161.2 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Aa_trans PF01490.13 EIW73966.1 - 8.5e-34 116.7 32.2 9.8e-34 116.5 22.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein S1FA PF04689.8 EIW73966.1 - 0.11 12.4 0.0 0.34 10.8 0.0 1.9 1 0 0 1 1 1 0 DNA binding protein S1FA NACHT PF05729.7 EIW73967.1 - 3.1e-10 39.9 0.0 1.1e-09 38.1 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW73967.1 - 1e-07 32.1 0.0 2.6e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW73967.1 - 0.00014 22.0 0.0 0.0025 17.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 EIW73967.1 - 0.00061 19.4 0.1 0.0011 18.6 0.1 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.17 EIW73967.1 - 0.0036 17.4 0.0 0.0069 16.5 0.0 1.4 1 0 0 1 1 1 1 RNA helicase ArgK PF03308.11 EIW73967.1 - 0.0043 15.8 0.0 0.0069 15.1 0.0 1.2 1 0 0 1 1 1 1 ArgK protein NTPase_1 PF03266.10 EIW73967.1 - 0.01 15.5 0.2 0.025 14.3 0.0 1.7 2 0 0 2 2 2 0 NTPase AAA_18 PF13238.1 EIW73967.1 - 0.015 15.5 0.0 0.028 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIW73967.1 - 0.019 14.5 0.0 0.042 13.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EIW73967.1 - 0.021 15.6 0.0 0.052 14.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EIW73967.1 - 0.032 13.8 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 EIW73967.1 - 0.032 13.7 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF258 PF03193.11 EIW73967.1 - 0.035 13.2 0.0 0.08 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EIW73967.1 - 0.037 13.1 0.0 0.07 12.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 EIW73967.1 - 0.04 13.6 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 EIW73967.1 - 0.056 13.7 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 EIW73967.1 - 0.057 13.2 0.1 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EIW73967.1 - 0.062 13.3 0.0 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF1746 PF08508.5 EIW73967.1 - 0.083 12.8 0.0 0.49 10.3 0.0 2.1 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1746) Arch_ATPase PF01637.13 EIW73967.1 - 0.097 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 EIW73967.1 - 0.12 11.8 0.1 0.29 10.5 0.1 1.6 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.9 EIW73967.1 - 0.13 11.9 0.1 0.22 11.1 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EIW73967.1 - 0.19 10.6 0.0 0.34 9.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein FAD_binding_4 PF01565.18 EIW73969.1 - 1.9e-19 69.5 4.0 4.3e-19 68.3 2.8 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EIW73969.1 - 1.9e-07 30.8 0.0 3.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like FemAB PF02388.11 EIW73971.1 - 0.78 8.3 5.5 1.6 7.3 3.8 1.4 1 0 0 1 1 1 0 FemAB family GP41 PF00517.12 EIW73971.1 - 2.3 7.7 6.5 4 6.9 4.5 1.3 1 0 0 1 1 1 0 Retroviral envelope protein DUF4218 PF13960.1 EIW73972.1 - 0.0029 17.0 0.1 0.0075 15.7 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF4218 PF13960.1 EIW73973.1 - 1.8e-06 27.3 0.0 3.2e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DEAD PF00270.24 EIW73976.1 - 4.9e-18 65.1 0.0 8.5e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW73976.1 - 7.3e-18 64.2 0.1 3.1e-17 62.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW73976.1 - 8.6e-06 25.6 0.0 2.4e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EIW73976.1 - 0.055 12.2 0.0 0.08 11.7 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain HSF_DNA-bind PF00447.12 EIW73978.1 - 3e-36 123.7 0.4 3e-36 123.7 0.2 1.5 2 0 0 2 2 2 1 HSF-type DNA-binding DUF904 PF06005.7 EIW73978.1 - 0.033 14.4 0.7 0.053 13.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Ets PF00178.17 EIW73978.1 - 0.094 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Ets-domain CoaE PF01121.15 EIW73979.1 - 1e-63 214.0 0.0 1.2e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 EIW73979.1 - 2.1e-07 31.3 0.4 2.1e-06 28.0 0.3 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW73979.1 - 2.4e-05 25.1 0.1 4.8e-05 24.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW73979.1 - 0.002 17.9 0.1 0.087 12.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EIW73979.1 - 0.023 14.6 0.1 0.049 13.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain FixQ PF05545.6 EIW73980.1 - 0.082 12.5 1.2 0.71 9.5 0.1 2.6 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ ESSS PF10183.4 EIW73980.1 - 0.22 11.9 1.7 75 3.7 0.0 3.3 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Pro-kuma_activ PF09286.6 EIW73981.1 - 2.6e-37 128.0 0.1 4.4e-37 127.2 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIW73981.1 - 1.5e-08 34.1 0.3 3.5e-08 32.9 0.1 1.5 1 1 0 1 1 1 1 Subtilase family CBM_25 PF03423.8 EIW73981.1 - 0.12 12.4 0.2 1.2 9.2 0.1 2.3 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) Pro-kuma_activ PF09286.6 EIW73983.1 - 2.5e-21 76.2 0.0 4.6e-21 75.3 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIW73983.1 - 1.5e-10 40.6 1.4 6.9e-10 38.5 0.1 2.4 2 1 1 3 3 3 1 Subtilase family F-box-like PF12937.2 EIW73984.1 - 2e-05 24.2 0.0 6.4e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW73984.1 - 0.00012 21.6 0.7 0.00025 20.5 0.0 1.9 2 0 0 2 2 2 1 F-box domain LRR_8 PF13855.1 EIW73984.1 - 0.024 14.4 0.1 4.4 7.1 0.0 3.6 3 0 0 3 3 3 0 Leucine rich repeat F-box-like PF12937.2 EIW73985.1 - 4.1e-10 39.2 0.8 1.2e-09 37.7 0.6 1.8 1 0 0 1 1 1 1 F-box-like Pro-kuma_activ PF09286.6 EIW73986.1 - 1.3e-34 119.3 0.0 2.1e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIW73986.1 - 4.5e-11 42.4 1.1 8.1e-11 41.5 0.8 1.4 1 0 0 1 1 1 1 Subtilase family PCI PF01399.22 EIW73987.1 - 4.1e-16 59.1 0.4 1.4e-15 57.4 0.1 2.1 2 0 0 2 2 2 1 PCI domain DUF3090 PF11290.3 EIW73987.1 - 0.031 13.7 0.3 0.069 12.6 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3090) DDE_Tnp_1_assoc PF13808.1 EIW73987.1 - 0.086 12.5 0.1 5.7 6.6 0.0 2.6 2 0 0 2 2 2 0 DDE_Tnp_1-associated TPR_8 PF13181.1 EIW73987.1 - 0.087 12.6 3.6 1.6 8.6 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_16 PF13191.1 EIW73987.1 - 0.13 12.2 5.7 0.64 9.9 1.5 2.2 2 0 0 2 2 2 0 AAA ATPase domain Caudo_TAP PF02413.12 EIW73987.1 - 0.34 11.0 2.5 0.81 9.8 1.7 1.6 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein TPR_6 PF13174.1 EIW73987.1 - 4.9 7.8 9.0 30 5.3 0.1 4.6 5 1 0 5 5 5 0 Tetratricopeptide repeat RPN7 PF10602.4 EIW73988.1 - 1.3e-51 174.5 1.2 1.9e-51 173.9 0.9 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EIW73988.1 - 1.3e-15 57.5 0.0 4.5e-15 55.8 0.0 2.0 2 0 0 2 2 2 1 PCI domain SAC3_GANP PF03399.11 EIW73988.1 - 0.001 18.6 0.7 0.0018 17.8 0.5 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family TPR_2 PF07719.12 EIW73988.1 - 0.54 10.2 3.4 4.2 7.5 0.2 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat ABC_tran PF00005.22 EIW73990.1 - 3.5e-24 85.6 0.0 5.8e-24 84.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIW73990.1 - 7.9e-12 45.7 0.0 6.3e-05 23.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EIW73990.1 - 2.9e-07 29.9 0.0 0.0052 16.0 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EIW73990.1 - 0.00016 21.6 0.1 0.0046 16.9 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EIW73990.1 - 0.001 18.5 0.0 0.002 17.5 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EIW73990.1 - 0.0035 17.4 0.0 0.57 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EIW73990.1 - 0.0046 16.5 0.0 0.16 11.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EIW73990.1 - 0.0093 16.7 0.0 0.037 14.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EIW73990.1 - 0.021 15.1 0.0 0.034 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 EIW73990.1 - 0.041 13.7 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 EIW73990.1 - 0.045 12.8 0.2 0.12 11.4 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.1 EIW73990.1 - 0.045 13.1 0.0 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EIW73990.1 - 0.048 13.1 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Miro PF08477.8 EIW73990.1 - 0.058 13.9 0.0 0.28 11.6 0.0 2.2 3 0 0 3 3 2 0 Miro-like protein AAA_18 PF13238.1 EIW73990.1 - 0.12 12.6 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain MutS_V PF00488.16 EIW73990.1 - 0.16 11.3 0.0 11 5.3 0.0 2.2 2 0 0 2 2 2 0 MutS domain V AAA_15 PF13175.1 EIW73990.1 - 0.38 9.7 0.0 0.54 9.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain HSF_DNA-bind PF00447.12 EIW73991.1 - 1.7e-35 121.3 1.2 1.7e-35 121.3 0.8 2.0 2 0 0 2 2 2 1 HSF-type DNA-binding Response_reg PF00072.19 EIW73991.1 - 4.6e-23 81.3 0.0 1.4e-22 79.7 0.1 1.9 2 0 0 2 2 2 1 Response regulator receiver domain F-box-like PF12937.2 EIW73992.1 - 1.9e-09 37.1 1.8 1.9e-09 37.1 1.2 2.9 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EIW73992.1 - 1.1 8.9 9.7 0.93 9.2 2.4 3.5 3 0 0 3 3 3 0 F-box domain Pro-kuma_activ PF09286.6 EIW73993.1 - 3.4e-32 111.4 0.5 6.9e-32 110.4 0.3 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIW73993.1 - 3.6e-12 46.0 0.3 3.6e-12 46.0 0.2 1.7 2 0 0 2 2 2 1 Subtilase family Snapin_Pallidin PF14712.1 EIW73996.1 - 0.026 14.8 1.5 0.049 13.9 1.0 1.4 1 0 0 1 1 1 0 Snapin/Pallidin Transposase_21 PF02992.9 EIW73997.1 - 1.5e-05 24.2 0.6 3.2e-05 23.1 0.1 1.7 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIW73997.1 - 0.0037 16.7 0.1 0.0075 15.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Adeno_terminal PF02459.10 EIW73997.1 - 2.2 6.3 4.9 3.4 5.7 3.4 1.2 1 0 0 1 1 1 0 Adenoviral DNA terminal protein HLH PF00010.21 EIW73999.1 - 1.8e-11 43.5 0.5 3.4e-11 42.6 0.3 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Formyl_trans_N PF00551.14 EIW74000.1 - 1.7e-37 128.7 0.0 4.3e-36 124.1 0.0 2.0 1 1 0 1 1 1 1 Formyl transferase Pkinase PF00069.20 EIW74003.1 - 9.8e-66 221.5 0.0 1.7e-65 220.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW74003.1 - 9.1e-39 133.0 0.0 4.3e-38 130.8 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW74003.1 - 9.3e-06 24.8 0.0 1.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW74003.1 - 0.0018 18.0 11.4 0.047 13.4 0.1 3.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Serglycin PF04360.7 EIW74003.1 - 0.012 15.3 2.0 0.11 12.2 0.2 2.5 2 0 0 2 2 2 0 Serglycin ERM PF00769.14 EIW74003.1 - 9.7 5.6 47.8 17 4.8 13.8 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Rubi_NSP_C PF12601.3 EIW74007.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.6 1 0 0 1 1 1 0 Rubivirus non-structural protein Hint_2 PF13403.1 EIW74008.1 - 0.0074 16.2 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 Hint domain Ta0938 PF11494.3 EIW74009.1 - 0.0037 17.3 0.0 0.0044 17.1 0.0 1.1 1 0 0 1 1 1 1 Ta0938 PIP49_C PF12260.3 EIW74009.1 - 0.13 11.6 0.0 0.13 11.6 0.0 1.0 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 DUF732 PF05305.9 EIW74010.1 - 0.0039 17.2 0.2 0.0055 16.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF732) AvrRpt-cleavage PF05627.6 EIW74010.1 - 0.082 11.9 0.0 0.62 9.1 0.0 2.1 2 0 0 2 2 2 0 Cleavage site for pathogenic type III effector avirulence factor Avr F-box-like PF12937.2 EIW74012.1 - 1.1e-06 28.2 0.1 3.1e-06 26.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EIW74012.1 - 0.065 12.9 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 F-box-like domain RasGEF_N PF00618.15 EIW74013.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 RasGEF N-terminal motif p450 PF00067.17 EIW74014.1 - 8.9e-72 242.0 0.0 1.1e-71 241.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW74015.1 - 4.1e-72 243.1 0.0 4.6e-72 243.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW74016.1 - 1.6e-34 119.2 0.0 4.2e-34 117.8 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW74018.1 - 2.5e-69 233.9 0.0 3.1e-69 233.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW74019.1 - 1.2e-38 132.9 0.0 2e-21 76.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 zf-C2H2 PF00096.21 EIW74020.1 - 2.2e-05 24.5 1.4 0.12 12.7 0.0 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW74020.1 - 0.00042 20.4 2.4 0.069 13.5 0.0 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIW74020.1 - 0.00054 20.0 0.5 0.11 12.6 0.1 2.3 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EIW74020.1 - 0.05 13.7 1.5 0.85 9.7 1.1 2.1 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 EIW74020.1 - 0.16 12.0 1.5 1.8 8.7 1.1 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Abhydrolase_6 PF12697.2 EIW74021.1 - 1.1e-10 41.7 0.3 2e-10 40.9 0.2 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW74021.1 - 8.3e-06 25.6 0.0 1.3e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW74021.1 - 0.00032 20.3 0.0 0.00047 19.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF427 PF04248.7 EIW74021.1 - 0.1 12.2 0.3 7.3 6.3 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF427) DUF382 PF04037.8 EIW74022.1 - 8.3e-59 197.0 1.1 1.4e-58 196.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.11 EIW74022.1 - 6.5e-19 67.0 6.6 1.3e-18 66.1 4.6 1.5 1 0 0 1 1 1 1 PSP Arrestin_C PF02752.17 EIW74023.1 - 9.6e-12 45.1 0.0 3.7e-10 40.0 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EIW74023.1 - 0.0011 18.8 0.0 0.0032 17.3 0.0 1.7 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain DUF3808 PF10300.4 EIW74024.1 - 6.4e-86 288.7 0.0 8.8e-86 288.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_19 PF14559.1 EIW74024.1 - 1.3e-08 35.0 2.3 6.1e-05 23.2 0.0 3.3 3 0 0 3 3 2 2 Tetratricopeptide repeat Apc3 PF12895.2 EIW74024.1 - 9.8e-07 28.8 0.1 0.0006 19.8 0.0 3.4 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EIW74024.1 - 2.5e-06 27.9 6.9 0.029 15.0 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIW74024.1 - 8.3e-06 25.6 0.4 0.77 9.7 0.0 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIW74024.1 - 1.6e-05 24.4 7.3 2.2 8.3 0.0 5.5 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EIW74024.1 - 1.7e-05 24.3 0.6 0.0051 16.4 0.0 3.3 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.1 EIW74024.1 - 0.00019 21.7 4.3 0.95 10.2 0.0 5.3 3 1 2 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIW74024.1 - 0.00095 18.7 0.2 32 4.6 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIW74024.1 - 0.0076 15.9 0.0 7.6 6.5 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIW74024.1 - 0.0096 15.4 0.0 29 4.5 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIW74024.1 - 0.022 15.2 4.1 12 6.6 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR_1 PF12854.2 EIW74024.1 - 0.032 13.7 0.1 12 5.4 0.0 3.0 3 0 0 3 3 3 0 PPR repeat TPR_4 PF07721.9 EIW74024.1 - 0.18 12.3 3.4 24 5.7 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat Sec10 PF07393.6 EIW74027.1 - 1.9e-121 406.5 0.0 1.1e-88 298.2 0.0 2.0 2 0 0 2 2 2 2 Exocyst complex component Sec10 F-box PF00646.28 EIW74027.1 - 0.022 14.3 0.0 0.044 13.4 0.0 1.5 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 EIW74027.1 - 0.052 13.2 0.3 0.18 11.5 0.2 2.0 2 0 0 2 2 2 0 F-box-like FliX PF10768.4 EIW74027.1 - 0.33 11.1 3.6 0.95 9.6 2.5 1.8 1 0 0 1 1 1 0 Class II flagellar assembly regulator eIF-4B PF06273.6 EIW74027.1 - 0.43 9.2 10.6 0.12 11.0 5.3 1.5 2 0 0 2 2 2 0 Plant specific eukaryotic initiation factor 4B Whi5 PF08528.6 EIW74028.1 - 0.00056 19.4 0.1 0.0011 18.4 0.1 1.5 1 0 0 1 1 1 1 Whi5 like PAT1 PF09770.4 EIW74028.1 - 7.7 4.6 14.6 8.6 4.4 10.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RF-1 PF00472.15 EIW74029.1 - 5.1e-36 122.9 3.3 8.3e-36 122.2 2.3 1.3 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EIW74029.1 - 1.2e-25 89.4 0.0 2.5e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 PCRF domain Lactamase_B PF00753.22 EIW74030.1 - 1.9e-10 40.7 7.3 2.6e-10 40.2 5.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EIW74030.1 - 2e-06 27.5 1.0 3e-06 26.9 0.5 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain p450 PF00067.17 EIW74031.1 - 8.3e-72 242.1 0.0 1e-71 241.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SPX PF03105.14 EIW74032.1 - 1.2e-15 58.0 0.0 4.3e-15 56.2 0.0 1.8 1 1 0 1 1 1 1 SPX domain zf-C3HC4_3 PF13920.1 EIW74032.1 - 1e-07 31.4 5.8 1.6e-07 30.8 4.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIW74032.1 - 2.5e-07 30.4 6.6 4.2e-07 29.7 4.6 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EIW74032.1 - 2.6e-07 30.5 8.8 4e-07 29.9 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW74032.1 - 5.4e-07 29.1 6.4 8.4e-07 28.5 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW74032.1 - 1.9e-06 27.6 8.0 3e-06 26.9 5.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EIW74032.1 - 2.8e-05 23.7 6.9 4.6e-05 23.0 4.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EIW74032.1 - 0.00014 21.4 5.4 0.00034 20.2 3.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 EIW74032.1 - 0.0017 17.8 3.5 0.0032 17.0 2.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 EIW74032.1 - 0.041 13.6 2.7 0.079 12.7 1.9 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EIW74032.1 - 0.063 13.3 4.4 0.15 12.1 3.0 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger MRVI1 PF05781.7 EIW74032.1 - 0.075 11.4 0.2 2.5 6.4 0.1 2.1 2 0 0 2 2 2 0 MRVI1 protein zf-Apc11 PF12861.2 EIW74032.1 - 0.19 11.5 1.1 0.34 10.7 0.7 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EIW74032.1 - 1.9 8.0 6.5 7.5 6.1 4.5 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-MIZ PF02891.15 EIW74032.1 - 2.9 7.4 6.4 5.4 6.6 4.4 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger p450 PF00067.17 EIW74033.1 - 1.5e-74 251.1 0.0 1.9e-74 250.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Phage_int_SAM_4 PF13495.1 EIW74034.1 - 0.02 15.1 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain RVT_3 PF13456.1 EIW74035.1 - 5.9e-07 29.1 0.1 9.9e-07 28.4 0.1 1.3 1 0 0 1 1 1 1 Reverse transcriptase-like RNase_H PF00075.19 EIW74035.1 - 0.012 15.9 0.0 0.015 15.6 0.0 1.1 1 0 0 1 1 1 0 RNase H RVT_thumb PF06817.9 EIW74036.1 - 0.024 14.2 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Reverse transcriptase thumb domain HTH_40 PF14493.1 EIW74036.1 - 0.09 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain p450 PF00067.17 EIW74037.1 - 2.5e-68 230.7 0.0 3.2e-68 230.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 SIR2 PF02146.12 EIW74038.1 - 2.4e-33 115.3 0.0 3.2e-31 108.4 0.0 2.5 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 EIW74038.1 - 0.0045 16.7 0.0 0.045 13.4 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain HhH-GPD PF00730.20 EIW74039.1 - 5.5e-08 33.0 0.0 5.7e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein TPR_11 PF13414.1 EIW74040.1 - 1.2e-12 47.3 2.6 3.3e-09 36.2 0.3 2.9 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EIW74040.1 - 1.6e-07 30.7 5.9 0.074 12.9 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIW74040.1 - 8.1e-06 25.2 4.0 0.13 11.9 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIW74040.1 - 0.00019 21.6 2.0 0.0028 17.9 0.2 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIW74040.1 - 0.00043 20.2 0.2 2.6 8.4 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIW74040.1 - 0.0005 20.6 4.3 0.004 17.8 1.2 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIW74040.1 - 0.009 16.5 5.9 0.073 13.7 0.6 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EIW74040.1 - 0.012 15.4 0.2 0.052 13.3 0.2 2.1 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIW74040.1 - 0.48 10.9 3.8 1 9.9 0.0 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF3886 PF13025.1 EIW74040.1 - 1.8 8.5 8.6 4.8 7.2 5.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) OPT PF03169.10 EIW74041.1 - 6e-146 487.4 46.5 6.8e-146 487.2 32.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.3 EIW74041.1 - 0.55 10.0 7.2 0.076 12.8 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) GPI-anchored PF10342.4 EIW74042.1 - 0.1 13.0 0.1 1.1 9.8 0.1 2.0 1 1 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Dus PF01207.12 EIW74043.1 - 1.9e-72 243.7 0.0 2.7e-72 243.2 0.0 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) SOR_SNZ PF01680.12 EIW74043.1 - 0.0016 18.0 0.0 0.42 10.1 0.0 2.8 2 1 1 3 3 3 2 SOR/SNZ family ThiG PF05690.9 EIW74043.1 - 0.0034 16.5 0.0 0.0056 15.7 0.0 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG DPBB_1 PF03330.13 EIW74044.1 - 3.2e-07 30.2 0.5 6e-07 29.3 0.4 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DPBB_1 PF03330.13 EIW74045.1 - 6.3e-08 32.5 1.0 1.7e-07 31.1 0.7 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIW74045.1 - 0.074 12.7 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Barwin family CTP_transf_1 PF01148.15 EIW74046.1 - 2.4e-10 40.5 2.7 4.4e-09 36.3 1.1 2.2 1 1 1 2 2 2 2 Cytidylyltransferase family Ribosomal_S8 PF00410.14 EIW74047.1 - 7.3e-27 93.7 0.2 1e-26 93.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_S17e PF00833.13 EIW74048.1 - 2.7e-57 191.7 0.1 3.2e-57 191.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 EIW74048.1 - 0.048 14.3 0.1 0.2 12.3 0.0 1.9 1 1 1 2 2 2 0 Blue/Ultraviolet sensing protein C terminal DPBB_1 PF03330.13 EIW74050.1 - 2.1e-08 34.0 0.0 3.9e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel His_Phos_1 PF00300.17 EIW74052.1 - 3.3e-28 98.7 0.0 4.4e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Amidase PF01425.16 EIW74053.1 - 7.6e-29 100.8 0.0 5.4e-21 74.9 0.0 3.0 2 1 0 2 2 2 2 Amidase Amidase PF01425.16 EIW74054.1 - 2.4e-78 263.9 0.0 1.2e-76 258.3 0.0 2.0 1 1 0 1 1 1 1 Amidase Zfx_Zfy_act PF04704.8 EIW74054.1 - 0.023 13.5 0.0 0.035 12.9 0.0 1.2 1 0 0 1 1 1 0 Zfx / Zfy transcription activation region His_Phos_2 PF00328.17 EIW74055.1 - 3.7e-41 141.5 0.0 5.4e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) COX4_pro PF03626.9 EIW74056.1 - 2.1 8.5 10.4 2.8 8.1 4.7 2.9 2 1 0 2 2 2 0 Prokaryotic Cytochrome C oxidase subunit IV p450 PF00067.17 EIW74058.1 - 9.6e-68 228.7 0.0 1.9e-67 227.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW74059.1 - 1.3e-58 198.6 0.1 2.5e-58 197.7 0.1 1.4 1 1 0 1 1 1 1 Cytochrome P450 AATase PF07247.7 EIW74062.1 - 0.013 14.0 0.0 0.25 9.8 0.0 2.0 2 0 0 2 2 2 0 Alcohol acetyltransferase DUF3684 PF12449.3 EIW74063.1 - 0 1170.6 0.0 0 1170.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 EIW74063.1 - 0.00021 20.9 0.2 0.0028 17.3 0.0 2.5 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MFS_1 PF07690.11 EIW74064.1 - 1.5e-27 96.2 49.5 6.7e-20 71.0 16.6 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EIW74064.1 - 9.1e-07 27.4 22.0 1.4e-06 26.8 15.3 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Spo7 PF03907.8 EIW74066.1 - 6.3e-14 52.0 1.6 6.3e-14 52.0 1.1 2.6 2 1 0 2 2 2 1 Spo7-like protein PHP PF02811.14 EIW74067.1 - 1e-12 48.1 0.1 1.5e-12 47.6 0.0 1.3 1 1 0 1 1 1 1 PHP domain Rnk_N PF14760.1 EIW74067.1 - 0.0082 16.2 0.2 0.02 14.9 0.1 1.7 1 0 0 1 1 1 1 Rnk N-terminus DUF1688 PF07958.6 EIW74069.1 - 3.7e-161 536.3 0.0 4.2e-161 536.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) MFS_2 PF13347.1 EIW74070.1 - 1.4e-08 33.5 25.8 3.1e-08 32.4 16.7 2.2 2 1 0 2 2 2 1 MFS/sugar transport protein PUCC PF03209.10 EIW74070.1 - 0.00039 19.2 2.1 0.00039 19.2 1.5 2.1 2 0 0 2 2 2 1 PUCC protein Acatn PF13000.2 EIW74070.1 - 0.012 14.1 0.9 0.024 13.1 0.3 1.7 2 0 0 2 2 2 0 Acetyl-coenzyme A transporter 1 ETF_QO PF05187.8 EIW74071.1 - 2.2e-27 95.2 0.0 3.7e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EIW74071.1 - 1e-07 31.2 0.0 5e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW74071.1 - 2.2e-07 30.8 0.3 8.2e-07 28.9 0.0 2.2 3 0 0 3 3 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIW74071.1 - 3.3e-05 23.8 0.1 5.7e-05 23.0 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW74071.1 - 4e-05 22.6 1.8 4.9e-05 22.3 0.6 1.6 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EIW74071.1 - 8.8e-05 21.1 0.4 0.00014 20.4 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EIW74071.1 - 0.00012 22.1 0.0 0.0002 21.4 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIW74071.1 - 0.00017 20.7 0.1 0.00032 19.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EIW74071.1 - 0.00022 21.0 0.1 0.00056 19.7 0.1 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding Thi4 PF01946.12 EIW74071.1 - 0.0005 19.2 0.2 0.0012 17.9 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EIW74071.1 - 0.00095 18.3 0.0 0.0015 17.6 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIW74071.1 - 0.0011 17.9 0.1 0.0022 16.9 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Fer4_7 PF12838.2 EIW74071.1 - 0.0028 18.0 0.3 0.0089 16.3 0.3 1.8 2 0 0 2 2 1 1 4Fe-4S dicluster domain Trp_halogenase PF04820.9 EIW74071.1 - 0.012 14.2 0.1 0.034 12.7 0.1 1.6 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox PF00070.22 EIW74071.1 - 0.052 13.9 0.4 2.4 8.6 0.2 3.2 4 0 0 4 4 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIW74071.1 - 0.1 11.4 0.1 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Fer4_9 PF13187.1 EIW74071.1 - 0.11 12.8 0.4 0.22 11.8 0.3 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 EIW74071.1 - 3.2 7.8 5.0 0.41 10.6 0.5 1.8 2 0 0 2 2 2 0 4Fe-4S binding domain GST_N_3 PF13417.1 EIW74072.1 - 5.6e-10 39.3 0.0 1e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW74072.1 - 5.8e-09 35.7 0.2 1.7e-08 34.1 0.1 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW74072.1 - 8.9e-07 28.8 0.0 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW74072.1 - 3.2e-05 23.8 0.0 7.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW74072.1 - 0.0073 16.7 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW74072.1 - 0.13 12.4 0.0 0.49 10.5 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain adh_short PF00106.20 EIW74073.1 - 2.9e-18 66.3 0.1 1.1e-17 64.4 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIW74073.1 - 4e-07 29.8 0.0 7.2e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIW74073.1 - 0.00038 20.3 0.0 0.00064 19.5 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIW74073.1 - 0.0014 18.7 0.3 0.0049 16.9 0.1 1.9 2 0 0 2 2 2 1 NADH(P)-binding Shikimate_DH PF01488.15 EIW74073.1 - 0.0044 17.1 0.1 0.0096 16.0 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EIW74073.1 - 0.0066 15.9 0.0 0.014 14.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EIW74073.1 - 0.015 14.2 0.0 0.016 14.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SMC_hinge PF06470.8 EIW74073.1 - 0.049 13.6 0.0 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 SMC proteins Flexible Hinge Domain AdoHcyase_NAD PF00670.16 EIW74073.1 - 0.061 13.1 0.1 0.099 12.4 0.1 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF3227 PF11537.3 EIW74073.1 - 0.11 12.5 0.2 0.36 10.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3227) GST_N_3 PF13417.1 EIW74074.1 - 7.4e-11 42.1 0.0 1.4e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW74074.1 - 4.3e-09 36.1 0.4 1.1e-07 31.6 0.0 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW74074.1 - 7.3e-08 32.2 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW74074.1 - 0.00094 19.1 0.0 0.0021 18.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW74074.1 - 0.0032 17.5 0.0 0.0093 16.1 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIW74074.1 - 0.038 14.4 0.0 0.073 13.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glyoxal_oxid_N PF07250.6 EIW74075.1 - 9.8e-39 132.8 0.0 1.4e-35 122.5 0.0 3.9 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EIW74075.1 - 2e-21 75.9 0.1 4.3e-21 74.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EIW74075.1 - 0.0012 18.5 14.2 0.39 10.5 0.1 5.9 6 0 0 6 6 6 3 Galactose oxidase, central domain adh_short PF00106.20 EIW74076.1 - 4.2e-19 69.0 0.0 1.2e-18 67.5 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIW74076.1 - 8.8e-09 35.2 0.0 2e-08 34.0 0.0 1.5 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EIW74076.1 - 1.5e-05 24.9 0.0 5.8e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIW74076.1 - 0.00042 20.3 0.1 0.00064 19.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EIW74076.1 - 0.0017 17.3 0.0 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EIW74076.1 - 0.0025 17.9 0.1 0.0051 16.9 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EIW74076.1 - 0.0087 15.0 0.2 0.013 14.5 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EIW74076.1 - 0.018 14.4 0.0 0.03 13.7 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EIW74076.1 - 0.031 13.3 0.0 0.055 12.5 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain AdoHcyase_NAD PF00670.16 EIW74076.1 - 0.032 14.0 0.0 0.075 12.8 0.0 1.6 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain MBOAT_2 PF13813.1 EIW74077.1 - 3.6e-18 65.4 4.3 4.4e-18 65.1 0.5 2.6 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family MBOAT PF03062.14 EIW74077.1 - 6.5e-06 25.5 5.2 6.5e-06 25.5 3.6 1.9 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EIW74078.1 - 6.8e-16 58.1 0.3 6.8e-16 58.1 0.2 1.9 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family CAS_CSE1 PF03378.10 EIW74080.1 - 1.6e-113 379.3 0.6 2.4e-113 378.7 0.4 1.2 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EIW74080.1 - 4.2e-89 298.7 0.0 7.1e-47 159.7 0.0 2.3 2 0 0 2 2 2 2 Cse1 IBN_N PF03810.14 EIW74080.1 - 3.6e-12 46.0 0.0 5.5e-11 42.2 0.0 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EIW74080.1 - 0.0019 18.1 0.5 0.061 13.2 0.0 3.3 4 0 0 4 4 4 1 Exportin 1-like protein BDM PF10684.4 EIW74080.1 - 0.05 13.8 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 Putative biofilm-dependent modulation protein MBOAT_2 PF13813.1 EIW74081.1 - 2.6e-16 59.4 0.3 2.6e-16 59.4 0.2 2.9 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family p450 PF00067.17 EIW74082.1 - 1.7e-70 237.8 0.0 3.3e-70 236.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 STAS_2 PF13466.1 EIW74082.1 - 0.052 13.5 0.7 0.15 12.1 0.5 1.8 1 0 0 1 1 1 0 STAS domain HSP70 PF00012.15 EIW74086.1 - 6e-31 107.0 0.0 6.4e-31 106.9 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Ribosomal_S20p PF01649.13 EIW74086.1 - 0.046 14.1 1.4 0.45 10.9 1.0 2.0 1 1 0 1 1 1 0 Ribosomal protein S20 DUF3834 PF12916.2 EIW74086.1 - 0.085 11.8 0.0 0.098 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) Peptidase_S32 PF05579.8 EIW74087.1 - 0.0032 16.5 0.2 0.005 15.8 0.1 1.2 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 HTH_39 PF14090.1 EIW74087.1 - 0.045 13.2 0.2 0.09 12.2 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain p450 PF00067.17 EIW74088.1 - 1.3e-55 188.8 0.0 6.3e-55 186.5 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Glucodextran_N PF09137.6 EIW74090.1 - 0.009 15.2 0.3 0.011 14.9 0.2 1.1 1 0 0 1 1 1 1 Glucodextranase, domain N Dimer_Tnp_hAT PF05699.9 EIW74091.1 - 3.8e-05 23.2 0.1 4e-05 23.1 0.1 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Helicase_C PF00271.26 EIW74098.1 - 1.7e-13 50.1 0.0 3.8e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIW74098.1 - 1.8e-13 50.3 0.0 4.3e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EIW74098.1 - 0.0001 22.1 0.0 0.00021 21.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Epiglycanin_C PF14654.1 EIW74099.1 - 0.011 15.7 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Ten1_2 PF15490.1 EIW74099.1 - 0.064 12.8 0.0 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 Telomere-capping, CST complex subunit FeThRed_B PF02943.10 EIW74102.1 - 0.12 12.1 1.5 0.19 11.4 1.0 1.3 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase catalytic beta chain Herpes_LMP1 PF05297.6 EIW74103.1 - 0.022 13.6 0.5 0.031 13.2 0.4 1.2 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) CATSPERG PF15064.1 EIW74105.1 - 0.0088 13.8 0.1 0.011 13.4 0.1 1.1 1 0 0 1 1 1 1 Cation channel sperm-associated protein subunit gamma CTC1_2 PF15491.1 EIW74105.1 - 0.1 11.6 0.1 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 DNA_methylase PF00145.12 EIW74107.1 - 2.4e-36 125.5 0.0 1e-20 74.1 0.0 4.3 2 2 0 2 2 2 2 C-5 cytosine-specific DNA methylase DNMT1-RFD PF12047.3 EIW74107.1 - 9.3e-12 44.8 0.6 2.1e-11 43.6 0.1 1.9 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain BAH PF01426.13 EIW74107.1 - 3.2e-11 43.0 0.0 6.7e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 BAH domain DUF77 PF01910.12 EIW74108.1 - 3.3e-05 23.4 0.0 3.9e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function DUF77 FUR PF01475.14 EIW74112.1 - 0.027 14.3 3.4 0.027 14.3 2.4 2.0 1 1 1 2 2 2 0 Ferric uptake regulator family RNase_H PF00075.19 EIW74118.1 - 4.2e-05 23.9 0.1 7.6e-05 23.0 0.0 1.4 2 0 0 2 2 2 1 RNase H DUF3778 PF12620.3 EIW74121.1 - 0.1 12.1 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3778) Trp_halogenase PF04820.9 EIW74123.1 - 0.0017 17.0 0.0 0.69 8.4 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Use1 PF09753.4 EIW74123.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 RVT_2 PF07727.9 EIW74125.1 - 1.3e-09 37.3 0.0 1.4e-09 37.2 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BAH PF01426.13 EIW74126.1 - 0.0018 18.0 0.1 0.0022 17.7 0.1 1.1 1 0 0 1 1 1 1 BAH domain XPG_I PF00867.13 EIW74128.1 - 3.1e-18 65.5 0.0 5.9e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 EIW74128.1 - 0.025 14.0 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 XPG domain containing XPG_N PF00752.12 EIW74128.1 - 0.076 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 XPG N-terminal domain Pribosyltran_N PF13793.1 EIW74130.1 - 0.13 12.0 0.1 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of ribose phosphate pyrophosphokinase Phage_30_3 PF08010.6 EIW74131.1 - 0.047 13.1 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage protein GP30.3 DUF1168 PF06658.7 EIW74135.1 - 0.021 14.3 1.4 0.027 14.0 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) EphA2_TM PF14575.1 EIW74135.1 - 0.043 14.1 0.0 0.05 13.9 0.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LRR_4 PF12799.2 EIW74142.1 - 0.19 11.4 3.3 6.7 6.4 0.1 4.5 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) Cauli_VI PF01693.11 EIW74143.1 - 8.3e-09 35.3 0.2 1.5e-08 34.5 0.1 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin Peptidase_C48 PF02902.14 EIW74145.1 - 3.5e-15 56.2 0.1 4.4e-15 55.9 0.1 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MgtE_N PF03448.12 EIW74146.1 - 0.074 13.3 0.3 0.15 12.4 0.1 1.6 2 0 0 2 2 2 0 MgtE intracellular N domain EST1_DNA_bind PF10373.4 EIW74147.1 - 6.7e-09 35.3 0.0 4.1e-06 26.2 0.0 2.3 2 0 0 2 2 2 2 Est1 DNA/RNA binding domain PIN_4 PF13638.1 EIW74147.1 - 6.8e-08 32.6 1.2 1.4e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 PIN domain DUF3136 PF11334.3 EIW74147.1 - 0.054 12.9 0.0 0.17 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) Transposase_21 PF02992.9 EIW74149.1 - 0.046 12.8 0.1 0.077 12.0 0.0 1.3 1 0 0 1 1 1 0 Transposase family tnp2 YebO PF13974.1 EIW74151.1 - 0.15 11.8 0.1 0.33 10.7 0.1 1.5 1 0 0 1 1 1 0 YebO-like protein Helicase_C PF00271.26 EIW74152.1 - 6.9e-18 64.2 0.0 2.1e-17 62.7 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIW74152.1 - 4.6e-11 42.4 0.0 7.7e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EIW74152.1 - 0.00017 21.4 0.0 0.00048 19.9 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EIW74152.1 - 0.0024 16.7 0.0 0.004 16.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SET PF00856.23 EIW74156.1 - 3.4e-12 46.9 0.2 4.1e-11 43.4 0.0 2.7 2 1 0 2 2 2 1 SET domain Glyco_hydro_28 PF00295.12 EIW74162.1 - 2.7e-52 177.7 9.5 3.7e-52 177.3 6.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Macoilin PF09726.4 EIW74163.1 - 5.9 5.0 8.0 7.8 4.6 5.5 1.1 1 0 0 1 1 1 0 Transmembrane protein WD40 PF00400.27 EIW74164.1 - 7.9e-52 171.3 16.3 1.3e-08 34.3 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EIW74164.1 - 0.0059 15.4 0.0 0.24 10.0 0.0 2.4 1 1 0 1 1 1 1 Nup133 N terminal like TrbI_Ftype PF09677.5 EIW74164.1 - 0.065 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Type-F conjugative transfer system protein (TrbI_Ftype) PQQ_2 PF13360.1 EIW74164.1 - 0.087 12.2 0.7 3.4 7.0 0.3 2.6 1 1 0 2 2 2 0 PQQ-like domain TFIIS_M PF07500.9 EIW74165.1 - 2.9e-33 114.3 2.7 3.3e-33 114.1 0.1 2.2 2 1 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EIW74165.1 - 2.9e-18 65.1 10.6 5e-18 64.4 7.4 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EIW74165.1 - 6.1e-14 51.2 0.8 6.1e-14 51.2 0.5 1.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain TF_Zn_Ribbon PF08271.7 EIW74165.1 - 0.11 11.8 1.4 0.22 10.8 1.0 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding DUF4296 PF14129.1 EIW74165.1 - 0.11 12.6 0.2 0.4 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) zinc_ribbon_5 PF13719.1 EIW74165.1 - 0.22 11.1 3.7 0.49 10.0 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EIW74165.1 - 0.39 10.4 3.7 0.88 9.3 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Borrelia_REV PF03978.8 EIW74165.1 - 0.59 9.8 10.0 6.1 6.5 0.1 3.4 2 2 1 3 3 3 0 Borrelia burgdorferi REV protein Aldo_ket_red PF00248.16 EIW74168.1 - 4.8e-47 160.1 0.0 5.4e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Phage_H_T_join PF05521.6 EIW74173.1 - 0.063 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 Phage head-tail joining protein Aldo_ket_red PF00248.16 EIW74175.1 - 4e-14 52.1 0.9 2.9e-11 42.7 0.6 3.2 1 1 0 1 1 1 1 Aldo/keto reductase family Glyco_transf_90 PF05686.7 EIW74175.1 - 0.09 11.4 0.1 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 90 Asp PF00026.18 EIW74176.1 - 1.3e-68 231.5 6.3 1.5e-68 231.3 4.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EIW74176.1 - 4.4e-05 23.8 3.3 0.00086 19.7 0.3 3.7 3 2 1 4 4 4 1 Aspartyl protease TAXi_C PF14541.1 EIW74176.1 - 0.001 18.6 0.1 0.0044 16.5 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EIW74176.1 - 0.0012 18.8 0.6 0.0036 17.2 0.4 1.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal AMP-binding PF00501.23 EIW74177.1 - 1.6e-65 221.1 0.0 2.7e-65 220.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 EIW74177.1 - 3.1e-34 119.1 0.0 9.5e-34 117.5 0.0 1.8 1 1 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 EIW74177.1 - 1.6e-08 34.6 0.0 4.6e-08 33.1 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EIW74177.1 - 1.4e-07 31.5 0.0 5.1e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW74177.1 - 0.0046 16.7 0.0 0.012 15.3 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EIW74177.1 - 0.05 12.4 0.0 0.12 11.1 0.0 1.6 1 0 0 1 1 1 0 Chlorophyllase enzyme ADH_N PF08240.7 EIW74178.1 - 9.3e-10 38.2 0.1 4.5e-08 32.8 0.0 2.5 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW74178.1 - 4.4e-07 29.5 0.4 0.00018 21.0 0.0 2.4 2 0 0 2 2 2 2 Zinc-binding dehydrogenase adh_short PF00106.20 EIW74178.1 - 0.00033 20.5 0.2 0.018 14.9 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EIW74178.1 - 0.00063 19.8 0.1 0.0029 17.6 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EIW74178.1 - 0.0018 18.0 0.2 0.0042 16.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.5 EIW74178.1 - 0.0061 16.2 0.1 2 8.0 0.0 2.3 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 EIW74178.1 - 0.081 12.3 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Aminotran_1_2 PF00155.16 EIW74179.1 - 1.5e-25 89.9 0.0 2.2e-25 89.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EIW74179.1 - 0.0035 15.9 0.0 0.006 15.1 0.0 1.3 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DUF898 PF05987.8 EIW74180.1 - 4.4e-05 22.5 1.3 5.1e-05 22.3 0.9 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF898) Nup84_Nup100 PF04121.8 EIW74182.1 - 3.9e-86 289.3 0.0 1e-85 287.9 0.0 1.7 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 Nic96 PF04097.9 EIW74182.1 - 0.0053 14.9 0.1 0.025 12.7 0.1 1.9 1 1 0 1 1 1 1 Nup93/Nic96 DUF4419 PF14388.1 EIW74183.1 - 2.7e-97 325.5 0.0 3.2e-97 325.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) PLDc PF00614.17 EIW74184.1 - 2.1e-19 68.6 1.7 1.2e-09 37.5 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EIW74184.1 - 2.3e-13 49.9 0.0 4.9e-07 29.5 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain HAMP PF00672.20 EIW74185.1 - 4.6e-46 154.8 22.8 1.9e-08 34.3 0.0 8.0 7 0 0 7 7 7 7 HAMP domain HATPase_c PF02518.21 EIW74185.1 - 2.5e-28 98.0 0.1 9.9e-28 96.0 0.1 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EIW74185.1 - 7.6e-23 80.6 0.2 2.9e-22 78.7 0.1 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EIW74185.1 - 1.1e-17 63.7 1.0 5.5e-17 61.5 0.7 2.4 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF2365 PF10157.4 EIW74185.1 - 1.6 8.6 16.2 24 4.7 0.0 6.9 5 3 0 5 5 5 0 Uncharacterized conserved protein (DUF2365) Syntaxin PF00804.20 EIW74185.1 - 3.1 8.0 6.8 13 5.9 0.1 4.5 4 1 0 4 4 4 0 Syntaxin Aldo_ket_red PF00248.16 EIW74186.1 - 1.4e-46 158.6 0.0 1.6e-46 158.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EIW74187.1 - 1.3e-47 162.0 0.0 1.5e-47 161.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Crp PF00325.15 EIW74188.1 - 0.074 12.5 0.1 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family WD40 PF00400.27 EIW74189.1 - 1.2e-120 389.5 46.5 1.2e-12 47.2 1.0 14.3 14 0 0 14 14 14 14 WD domain, G-beta repeat eIF2A PF08662.6 EIW74189.1 - 5.1e-17 62.2 0.0 3.9e-06 26.7 0.0 4.9 2 2 2 4 4 4 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EIW74189.1 - 4.9e-12 45.2 10.8 0.51 10.0 0.0 10.6 11 0 0 11 11 11 4 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EIW74189.1 - 6.5e-09 34.4 6.6 0.11 10.6 0.0 6.5 4 2 3 7 7 7 4 Nucleoporin Nup120/160 DPPIV_N PF00930.16 EIW74189.1 - 0.00094 17.8 0.1 9.4 4.7 0.0 5.7 5 2 0 5 5 5 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Proteasome_A_N PF10584.4 EIW74189.1 - 0.11 11.8 13.6 4.9 6.5 0.0 7.2 8 0 0 8 8 8 0 Proteasome subunit A N-terminal signature IKI3 PF04762.7 EIW74189.1 - 0.27 8.9 0.0 1.2 6.8 0.0 2.1 2 1 0 2 2 2 0 IKI3 family Peptidase_M48 PF01435.13 EIW74190.1 - 3.4e-44 151.0 0.5 4.6e-44 150.6 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M48 Acetyltransf_3 PF13302.1 EIW74191.1 - 2.3e-12 47.2 0.0 3.4e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW74191.1 - 2.6e-05 24.1 0.1 5e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EIW74191.1 - 0.082 12.7 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Abhydrolase_3 PF07859.8 EIW74192.1 - 5.4e-24 84.9 0.1 1.3e-23 83.6 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIW74192.1 - 5.5e-13 48.2 0.0 8.3e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EIW74192.1 - 7.8e-06 25.7 0.1 1.4e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EIW74192.1 - 0.0066 15.2 0.7 0.041 12.5 0.5 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW74193.1 - 9.8e-24 84.1 0.1 1e-22 80.7 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIW74193.1 - 3.7e-09 35.6 0.0 4.7e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EIW74193.1 - 5.3e-05 22.9 0.0 9.5e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EIW74193.1 - 0.11 11.2 0.3 0.39 9.3 0.2 1.8 1 1 0 1 1 1 0 Carboxylesterase family Aa_trans PF01490.13 EIW74194.1 - 5.2e-28 97.6 32.2 5.2e-28 97.6 22.3 1.5 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Spore_permease PF03845.8 EIW74194.1 - 0.00063 18.4 9.7 0.00063 18.4 6.7 2.5 3 1 0 3 3 3 1 Spore germination protein DUF4448 PF14610.1 EIW74197.1 - 2.2e-07 30.5 0.0 3.4e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 EIW74197.1 - 0.00095 19.5 0.8 0.0019 18.6 0.6 1.6 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4066 PF13278.1 EIW74198.1 - 4.8e-17 61.7 0.0 1.3e-16 60.2 0.0 1.7 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EIW74198.1 - 4.6e-05 22.9 0.0 9.8e-05 21.8 0.0 1.5 1 1 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EIW74199.1 - 3.3e-10 39.4 0.3 7.3e-10 38.3 0.2 1.6 1 1 0 1 1 1 1 Putative amidotransferase Pyr_redox_3 PF13738.1 EIW74200.1 - 2e-22 80.2 0.1 3.7e-19 69.5 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIW74200.1 - 1.1e-18 66.8 0.0 3.4e-18 65.1 0.0 1.7 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EIW74200.1 - 3.9e-09 35.8 0.1 4.3e-05 22.6 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EIW74200.1 - 4.8e-09 36.3 0.0 0.0018 18.1 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW74200.1 - 7.3e-09 35.5 0.5 1.9e-07 31.0 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIW74200.1 - 1.7e-07 30.4 0.2 1e-05 24.6 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EIW74200.1 - 1.9e-06 27.7 1.1 0.033 13.9 0.0 4.1 4 0 0 4 4 4 1 FAD-NAD(P)-binding Pyr_redox PF00070.22 EIW74200.1 - 3.8e-06 27.2 2.3 0.014 15.7 0.1 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIW74200.1 - 3.5e-05 23.0 0.0 0.00072 18.7 0.0 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EIW74200.1 - 0.00012 21.3 0.0 0.029 13.4 0.0 2.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EIW74200.1 - 0.00029 19.8 2.3 0.035 12.9 0.1 2.4 2 0 0 2 2 2 2 FAD binding domain 3HCDH_N PF02737.13 EIW74200.1 - 0.00059 19.5 1.6 0.0009 18.9 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EIW74200.1 - 0.00079 19.5 0.4 0.67 10.0 0.0 3.0 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EIW74200.1 - 0.0026 16.6 1.4 0.098 11.5 0.1 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_7 PF13241.1 EIW74200.1 - 0.0048 17.1 0.6 0.21 11.8 0.3 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.9 EIW74200.1 - 0.0064 15.0 3.3 0.1 11.0 0.4 2.8 3 0 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 EIW74200.1 - 0.02 14.0 2.6 0.18 10.8 0.1 2.5 3 0 0 3 3 3 0 Thi4 family MTS_N PF08468.6 EIW74200.1 - 0.037 13.8 0.1 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain N-terminal AlaDh_PNT_C PF01262.16 EIW74200.1 - 0.041 13.4 1.0 7.9 6.0 0.2 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 EIW74200.1 - 0.065 13.0 0.1 0.29 10.9 0.0 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EIW74200.1 - 0.074 12.1 0.1 11 5.1 0.0 2.3 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EIW74200.1 - 0.1 11.5 0.3 4.4 6.1 0.8 2.9 2 1 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EIW74200.1 - 0.17 10.9 2.6 6.9 5.6 0.2 2.2 2 0 0 2 2 2 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 EIW74200.1 - 0.18 11.1 0.1 0.39 10.0 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.1 EIW74200.1 - 0.25 11.3 3.1 0.65 9.9 0.1 2.7 3 1 1 4 4 4 0 NADH(P)-binding Aa_trans PF01490.13 EIW74201.1 - 3.3e-31 108.1 30.7 4.8e-31 107.6 21.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF1469 PF07332.6 EIW74201.1 - 0.26 11.0 0.1 0.26 11.0 0.1 3.2 4 1 0 4 4 4 0 Protein of unknown function (DUF1469) UBACT PF02134.16 EIW74201.1 - 0.98 9.0 4.8 0.19 11.3 0.1 2.1 2 0 0 2 2 2 0 Repeat in ubiquitin-activating (UBA) protein AMP-binding PF00501.23 EIW74202.1 - 2.5e-61 207.3 0.0 3.1e-61 207.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 EIW74202.1 - 3.3e-32 112.5 0.2 8.6e-32 111.1 0.1 1.8 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EIW74202.1 - 2.9e-10 40.4 0.8 1.4e-09 38.1 0.2 2.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family PP-binding PF00550.20 EIW74202.1 - 3.4e-10 40.0 0.0 8.9e-10 38.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 EIW74202.1 - 0.00061 19.5 0.0 0.0019 17.9 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EIW74202.1 - 0.04 13.5 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 EIW74202.1 - 0.1 11.4 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme PE-PPE PF08237.6 EIW74202.1 - 0.14 11.5 0.0 0.36 10.2 0.0 1.6 1 0 0 1 1 1 0 PE-PPE domain DUF1656 PF07869.7 EIW74203.1 - 0.012 15.3 1.6 0.036 13.8 1.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) DUF3816 PF12822.2 EIW74203.1 - 0.062 13.2 5.4 0.38 10.6 4.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) Cyclin_N PF00134.18 EIW74205.1 - 0.089 12.3 0.1 3.8 7.0 0.0 2.7 2 1 0 2 2 2 0 Cyclin, N-terminal domain DUF2945 PF11160.3 EIW74206.1 - 0.18 11.6 3.0 0.28 11.0 2.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2945) RicinB_lectin_2 PF14200.1 EIW74208.1 - 1.7e-08 34.7 0.4 0.00014 22.1 0.0 2.2 2 0 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like PMI_typeI PF01238.16 EIW74209.1 - 9.4e-110 367.0 0.0 1.1e-109 366.8 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 EIW74209.1 - 0.00017 20.9 0.0 0.24 10.9 0.0 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EIW74209.1 - 0.0028 17.3 0.0 0.94 9.1 0.0 2.9 3 0 0 3 3 3 2 AraC-like ligand binding domain Fungal_trans_2 PF11951.3 EIW74209.1 - 0.1 11.1 0.0 0.2 10.2 0.0 1.4 1 1 0 1 1 1 0 Fungal specific transcription factor domain MFS_1 PF07690.11 EIW74210.1 - 1.9e-26 92.6 52.3 1.3e-23 83.3 28.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EIW74210.1 - 0.0016 18.4 0.9 0.0016 18.4 0.6 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) MinC_C PF03775.11 EIW74210.1 - 0.14 11.8 0.1 2.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Septum formation inhibitor MinC, C-terminal domain Acid_PPase PF12689.2 EIW74211.1 - 7.7e-32 110.2 0.0 2.6e-28 98.7 0.0 2.0 1 1 1 2 2 2 2 Acid Phosphatase Acid_PPase PF12689.2 EIW74212.1 - 0.047 13.3 0.0 0.063 12.9 0.0 1.1 1 0 0 1 1 1 0 Acid Phosphatase Solute_trans_a PF03619.11 EIW74213.1 - 1.2e-70 238.0 12.7 1.4e-70 237.7 8.8 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha RicinB_lectin_2 PF14200.1 EIW74214.1 - 1.4e-24 86.4 0.1 3.3e-13 49.9 0.1 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EIW74214.1 - 1.2e-05 25.3 0.0 0.00024 21.1 0.0 2.2 1 1 0 1 1 1 1 Ricin-type beta-trefoil lectin domain DUF824 PF05688.6 EIW74214.1 - 0.32 10.6 1.2 9.6 5.9 0.1 2.4 1 1 1 2 2 2 0 Salmonella repeat of unknown function (DUF824) Transposase_21 PF02992.9 EIW74217.1 - 4.3e-12 45.6 0.0 9.6e-12 44.4 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EIW74217.1 - 0.00034 20.0 0.0 0.00062 19.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) F-box-like PF12937.2 EIW74218.1 - 0.007 16.0 0.2 0.042 13.5 0.0 2.5 2 0 0 2 2 2 1 F-box-like TPR_16 PF13432.1 EIW74219.1 - 0.4 11.4 4.0 1.6 9.5 2.7 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Pyr_redox_3 PF13738.1 EIW74220.1 - 3.7e-20 72.8 0.0 2.8e-17 63.4 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIW74220.1 - 2.1e-11 42.7 0.0 0.00017 19.9 0.0 3.1 3 1 0 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EIW74220.1 - 6.2e-11 42.5 0.0 7.2e-05 22.7 0.0 2.9 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW74220.1 - 1.9e-10 40.5 0.1 3.6e-08 33.2 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EIW74220.1 - 8e-10 38.1 0.2 2.1e-05 23.6 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EIW74220.1 - 2e-07 30.2 0.0 4.8e-05 22.4 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EIW74220.1 - 1.4e-06 28.1 0.0 0.085 12.6 0.0 4.0 3 1 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 EIW74220.1 - 5.2e-06 26.7 1.8 0.1 12.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW74220.1 - 0.00011 20.7 0.4 0.3 9.5 0.5 3.0 3 0 0 3 3 3 2 HI0933-like protein Shikimate_DH PF01488.15 EIW74220.1 - 0.00014 21.9 0.5 0.25 11.4 0.0 3.1 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EIW74220.1 - 0.00033 19.6 1.3 0.023 13.5 0.3 2.4 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 EIW74220.1 - 0.00046 19.8 0.5 0.0019 17.8 0.1 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EIW74220.1 - 0.0013 17.7 0.8 0.17 10.6 0.4 2.7 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_7 PF13241.1 EIW74220.1 - 0.0015 18.7 0.0 0.065 13.4 0.0 2.4 3 0 0 3 3 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.2 EIW74220.1 - 0.0049 16.0 0.7 0.013 14.6 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EIW74220.1 - 0.0068 15.5 0.7 2.9 6.9 0.1 2.5 3 0 0 3 3 3 2 Thi4 family AlaDh_PNT_C PF01262.16 EIW74220.1 - 0.044 13.3 0.2 11 5.5 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Amino_oxidase PF01593.19 EIW74220.1 - 0.069 12.2 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase THF_DHG_CYH_C PF02882.14 EIW74220.1 - 0.15 11.1 0.0 1.5 7.9 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 EIW74220.1 - 0.38 10.7 2.3 2.2 8.2 0.6 2.4 2 0 0 2 2 2 0 NADH(P)-binding Abhydrolase_6 PF12697.2 EIW74221.1 - 1.6e-28 100.1 0.0 2.2e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW74221.1 - 9.6e-22 77.6 0.0 5.7e-21 75.1 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW74221.1 - 7.3e-14 51.7 0.0 1.2e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EIW74221.1 - 2e-05 24.3 0.0 4.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.16 EIW74221.1 - 4.2e-05 22.8 0.1 0.071 12.3 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EIW74221.1 - 0.0013 18.5 0.0 0.031 14.1 0.0 2.4 2 0 0 2 2 2 1 Putative lysophospholipase DLH PF01738.13 EIW74221.1 - 0.0082 15.4 0.0 0.26 10.5 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF2048 PF09752.4 EIW74221.1 - 0.011 14.6 0.1 0.036 12.9 0.1 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) PGAP1 PF07819.8 EIW74221.1 - 0.034 13.7 0.1 0.095 12.2 0.1 1.7 1 1 0 1 1 1 0 PGAP1-like protein BAAT_C PF08840.6 EIW74221.1 - 0.064 12.9 0.0 5.7 6.5 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 EIW74221.1 - 0.087 12.2 0.0 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Pyr_redox_3 PF13738.1 EIW74222.1 - 4.9e-20 72.4 0.0 1.1e-11 45.1 0.0 3.3 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIW74222.1 - 5.3e-14 51.3 0.0 1.2e-06 27.0 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EIW74222.1 - 5.4e-09 35.9 0.1 3.5e-08 33.3 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIW74222.1 - 2.3e-08 34.1 0.0 0.0028 17.5 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW74222.1 - 5.6e-06 25.4 0.0 0.0001 21.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 EIW74222.1 - 8.1e-05 21.6 0.2 0.42 9.4 0.0 3.7 4 0 0 4 4 4 2 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.19 EIW74222.1 - 0.00017 20.8 0.4 0.00074 18.7 0.1 2.1 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase 3HCDH_N PF02737.13 EIW74222.1 - 0.00065 19.3 0.2 0.0015 18.1 0.1 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EIW74222.1 - 0.0041 16.8 0.1 0.039 13.7 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 EIW74222.1 - 0.0056 15.8 0.8 0.0056 15.8 0.5 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW74222.1 - 0.0061 15.4 3.7 0.0083 15.0 0.6 2.3 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.14 EIW74222.1 - 0.019 14.1 0.3 6.7 5.8 0.0 3.0 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 EIW74222.1 - 0.037 12.4 4.4 0.18 10.2 1.0 2.7 3 0 0 3 3 3 0 HI0933-like protein Shikimate_DH PF01488.15 EIW74222.1 - 0.071 13.2 1.4 4.5 7.3 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EIW74222.1 - 0.097 13.0 3.2 0.12 12.8 0.3 2.4 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase PA PF02225.17 EIW74222.1 - 0.15 11.7 0.2 1.8 8.2 0.0 2.5 3 0 0 3 3 3 0 PA domain Thi4 PF01946.12 EIW74222.1 - 0.19 10.8 0.6 2.5 7.1 0.0 2.2 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.16 EIW74222.1 - 0.29 10.7 4.3 1.4 8.4 0.0 2.8 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EIW74222.1 - 0.85 9.3 2.1 0.62 9.7 0.3 1.5 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GIDA PF01134.17 EIW74222.1 - 1.2 7.9 4.4 0.32 9.8 0.8 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A CBM_5_12 PF02839.9 EIW74223.1 - 6.7e-08 32.0 6.9 2.2e-07 30.3 4.8 2.0 1 0 0 1 1 1 1 Carbohydrate binding domain Glyco_hydro_18 PF00704.23 EIW74224.1 - 1.2e-08 34.7 0.6 1.5e-08 34.4 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.23 EIW74227.1 - 5.5e-09 35.9 2.4 6.9e-09 35.5 1.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 UPF0121 PF03661.8 EIW74227.1 - 0.2 10.8 0.1 0.28 10.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0121) GST_N_3 PF13417.1 EIW74228.1 - 8.5e-08 32.3 0.2 4.5e-07 29.9 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW74228.1 - 1.4e-05 24.9 0.0 2.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW74228.1 - 0.023 14.8 0.0 0.035 14.2 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain F-box-like PF12937.2 EIW74229.1 - 0.001 18.7 0.1 0.001 18.7 0.1 2.5 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EIW74229.1 - 0.0034 17.0 0.1 0.013 15.1 0.0 2.0 1 0 0 1 1 1 1 F-box domain DUF4359 PF14271.1 EIW74234.1 - 5.7e-07 29.8 0.0 0.0021 18.4 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4359) Rad60-SLD PF11976.3 EIW74235.1 - 8.1e-07 28.6 0.0 8.7e-07 28.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EIW74235.1 - 7.1e-05 22.1 0.0 7.1e-05 22.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EIW74236.1 - 1.5e-05 24.5 0.0 2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.3 EIW74236.1 - 0.11 12.4 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 GLUT4 regulating protein TUG Rad60-SLD PF11976.3 EIW74237.1 - 6.5e-12 44.9 0.0 7.7e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EIW74237.1 - 1.7e-05 24.0 0.0 2.2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.3 EIW74237.1 - 0.13 12.1 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 GLUT4 regulating protein TUG ATG22 PF11700.3 EIW74238.1 - 7e-149 496.3 5.2 7.9e-149 496.1 3.6 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EIW74238.1 - 3.1e-09 36.0 45.9 3.5e-06 25.9 3.3 3.4 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF4131 PF13567.1 EIW74238.1 - 0.019 14.3 0.1 0.019 14.3 0.1 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) Herpes_UL16 PF03044.9 EIW74238.1 - 0.21 10.5 0.5 0.32 9.9 0.0 1.5 2 0 0 2 2 2 0 Herpesvirus UL16/UL94 family DUF3839 PF12943.2 EIW74239.1 - 0.12 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3839) BBE PF08031.7 EIW74240.1 - 1.7e-11 43.8 0.8 2.6e-11 43.2 0.5 1.3 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EIW74240.1 - 0.024 13.7 0.1 0.027 13.5 0.1 1.1 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding PARP PF00644.15 EIW74242.1 - 7.4e-12 45.1 0.1 1.4e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 EIW74242.1 - 2.1e-07 30.4 0.0 4.6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIW74242.1 - 0.056 13.1 0.0 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B DNA_binding_1 PF01035.15 EIW74243.1 - 6.8e-12 44.9 0.0 1.1e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain NOA36 PF06524.7 EIW74243.1 - 1.8 7.7 5.0 2 7.5 3.5 1.1 1 0 0 1 1 1 0 NOA36 protein Aldo_ket_red PF00248.16 EIW74244.1 - 1.1e-42 145.8 0.0 1.3e-41 142.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 EIW74247.1 - 2.3e-50 171.2 12.8 4e-50 170.4 8.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW74247.1 - 5.3e-16 58.2 18.6 1.8e-13 49.9 1.3 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter OATP PF03137.15 EIW74247.1 - 0.0012 17.0 2.2 0.0012 17.0 1.5 2.1 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family 2TM PF13239.1 EIW74247.1 - 0.071 13.1 9.6 1.2 9.2 0.2 4.0 5 0 0 5 5 5 0 2TM domain F-box-like PF12937.2 EIW74248.1 - 6e-10 38.6 0.3 1.4e-09 37.4 0.2 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EIW74248.1 - 0.0024 17.5 0.0 0.24 11.1 0.0 3.1 4 0 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.2 EIW74248.1 - 0.083 12.5 0.1 4 7.1 0.0 3.4 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Abhydrolase_3 PF07859.8 EIW74250.1 - 5.7e-29 101.2 0.0 8.1e-29 100.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIW74250.1 - 5.4e-06 25.2 0.0 1.3e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EIW74250.1 - 0.019 14.1 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF1212 PF06738.7 EIW74251.1 - 5.2e-38 130.4 10.5 5.6e-37 127.0 1.8 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EIW74251.1 - 1.7e-16 60.3 5.4 1.7e-16 60.3 3.7 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF3815) F-box-like PF12937.2 EIW74253.1 - 6e-08 32.2 0.0 2.1e-07 30.5 0.0 2.0 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 EIW74254.1 - 1.5e-28 97.5 5.5 5.3e-06 26.0 0.1 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat AA_permease_2 PF13520.1 EIW74256.1 - 2.7e-69 233.7 48.4 3.3e-69 233.4 33.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIW74256.1 - 8.3e-20 70.5 43.8 1.3e-19 69.9 30.4 1.2 1 0 0 1 1 1 1 Amino acid permease DUF3353 PF11833.3 EIW74257.1 - 0.1 12.0 0.7 0.26 10.7 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) F-box-like PF12937.2 EIW74261.1 - 3.7e-05 23.3 1.8 4.9e-05 22.9 0.1 2.1 2 0 0 2 2 2 1 F-box-like DUF4218 PF13960.1 EIW74263.1 - 0.00069 19.0 0.2 0.0012 18.3 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) KOW PF00467.24 EIW74264.1 - 4.3e-07 29.4 0.7 0.06 13.0 0.0 4.8 4 0 0 4 4 4 2 KOW motif YolD PF08863.5 EIW74264.1 - 0.057 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 YolD-like protein HMG_box PF00505.14 EIW74265.1 - 8e-06 26.0 9.6 0.0017 18.5 3.3 2.4 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EIW74265.1 - 3.8e-05 23.9 7.3 0.01 16.1 2.2 2.4 2 0 0 2 2 2 2 HMG-box domain ADSL_C PF10397.4 EIW74265.1 - 0.0019 18.1 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus ubiquitin PF00240.18 EIW74265.1 - 0.0072 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rubi_NSP_C PF12601.3 EIW74265.1 - 0.099 12.5 0.2 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 Rubivirus non-structural protein Rubi_NSP_C PF12601.3 EIW74266.1 - 0.051 13.4 0.2 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Rubivirus non-structural protein Joubert PF15392.1 EIW74267.1 - 0.064 12.4 0.0 0.087 12.0 0.0 1.1 1 0 0 1 1 1 0 Joubert syndrome-associated WD40 PF00400.27 EIW74268.1 - 5.2e-19 67.3 0.6 0.0062 16.3 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat BBS2_Mid PF14783.1 EIW74268.1 - 0.031 14.0 0.0 8.6 6.1 0.0 2.4 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region NAGLU PF05089.7 EIW74268.1 - 0.084 11.6 0.1 0.17 10.6 0.0 1.4 2 0 0 2 2 2 0 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain PQQ_3 PF13570.1 EIW74268.1 - 0.088 13.1 0.3 1.8 8.9 0.0 3.0 3 0 0 3 3 3 0 PQQ-like domain SNF2_N PF00176.18 EIW74269.1 - 2.5e-68 230.0 0.0 2.5e-67 226.7 0.0 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW74269.1 - 1.2e-13 50.7 0.0 3.1e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW74269.1 - 9e-07 28.8 0.0 8.8e-06 25.6 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EIW74269.1 - 0.0017 17.2 0.0 0.017 13.9 0.0 2.4 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 DUF805 PF05656.9 EIW74272.1 - 0.096 12.5 5.4 0.32 10.8 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF805) MFS_1 PF07690.11 EIW74274.1 - 6.8e-25 87.5 61.1 4e-20 71.8 27.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CBFD_NFYB_HMF PF00808.18 EIW74275.1 - 2.8e-08 33.7 0.1 5e-08 32.8 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RILP PF11461.3 EIW74275.1 - 0.21 11.7 1.2 0.41 10.8 0.0 2.0 2 0 0 2 2 2 0 Rab interacting lysosomal protein Ogr_Delta PF04606.7 EIW74276.1 - 0.093 12.3 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger Thaumatin PF00314.12 EIW74277.1 - 2e-65 220.2 12.9 2.3e-65 220.0 8.9 1.0 1 0 0 1 1 1 1 Thaumatin family Thaumatin PF00314.12 EIW74278.1 - 1.4e-64 217.4 9.0 1.6e-64 217.2 6.2 1.0 1 0 0 1 1 1 1 Thaumatin family ICMT PF04140.9 EIW74279.1 - 3e-14 52.9 0.4 1.9e-13 50.4 0.0 2.3 3 0 0 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIW74279.1 - 1.9e-13 50.4 1.2 2.9e-12 46.6 0.3 2.4 2 0 0 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EIW74279.1 - 2.8e-05 22.8 0.0 4e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF202 PF02656.10 EIW74279.1 - 7.7 6.8 8.1 8.9 6.6 0.6 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Terpene_synth_C PF03936.11 EIW74280.1 - 0.045 12.9 0.0 0.065 12.4 0.0 1.2 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain SnoaL_4 PF13577.1 EIW74281.1 - 2.7e-11 43.4 0.0 3.2e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain F-box-like PF12937.2 EIW74282.1 - 0.0003 20.4 0.0 0.00089 18.9 0.0 1.9 1 0 0 1 1 1 1 F-box-like TRI5 PF06330.6 EIW74283.1 - 1.6e-18 66.5 0.0 2.1e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Sugar_tr PF00083.19 EIW74283.1 - 0.048 12.2 0.1 0.072 11.6 0.0 1.2 1 0 0 1 1 1 0 Sugar (and other) transporter Terpene_synth_C PF03936.11 EIW74283.1 - 0.1 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain DUF4590 PF15257.1 EIW74283.1 - 0.1 12.4 0.1 11 5.9 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4590) GMC_oxred_C PF05199.8 EIW74284.1 - 5.9e-32 110.9 0.0 9.9e-32 110.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EIW74284.1 - 2.2e-13 50.0 0.1 3.7e-13 49.3 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase IMS_HHH PF11798.3 EIW74284.1 - 0.041 13.9 0.1 0.95 9.6 0.0 2.9 3 0 0 3 3 3 0 IMS family HHH motif Thaumatin PF00314.12 EIW74285.1 - 8.7e-64 214.8 11.6 9.9e-64 214.7 8.0 1.0 1 0 0 1 1 1 1 Thaumatin family F-box-like PF12937.2 EIW74286.1 - 0.0013 18.3 0.0 2.4 7.9 0.0 2.9 2 0 0 2 2 2 2 F-box-like zf-C2H2_4 PF13894.1 EIW74286.1 - 1.4 9.4 5.1 1.7 9.1 1.9 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Phosphodiest PF01663.17 EIW74287.1 - 5.6e-11 42.3 0.2 9.9e-11 41.5 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EIW74287.1 - 0.00029 20.1 0.0 0.00048 19.4 0.0 1.4 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EIW74287.1 - 0.038 13.3 0.0 0.057 12.7 0.0 1.2 1 0 0 1 1 1 0 Metalloenzyme superfamily DUF1501 PF07394.7 EIW74287.1 - 0.15 10.8 0.2 0.25 10.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF229 PF02995.12 EIW74287.1 - 1.2 7.4 0.1 1.6 7.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) TFIIIC_sub6 PF10419.4 EIW74288.1 - 5.3e-09 35.3 0.1 7.8e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 TFIIIC subunit Dynamin_N PF00350.18 EIW74290.1 - 6.1e-15 55.4 0.0 6e-14 52.2 0.0 2.5 2 1 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EIW74290.1 - 2.5e-07 30.6 0.0 0.029 14.3 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.1 EIW74290.1 - 1.1e-06 28.7 0.2 3.2e-06 27.2 0.0 1.9 2 1 1 3 3 3 1 AAA ATPase domain DUF258 PF03193.11 EIW74290.1 - 0.00037 19.7 0.0 0.018 14.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EIW74290.1 - 0.0019 17.6 1.6 0.0024 17.3 0.0 2.0 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Abhydrolase_6 PF12697.2 EIW74290.1 - 0.0041 17.0 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Septin PF00735.13 EIW74290.1 - 0.0044 16.0 0.5 0.013 14.5 0.0 2.0 3 0 0 3 3 3 1 Septin SRPRB PF09439.5 EIW74290.1 - 0.008 15.4 0.1 0.062 12.5 0.0 2.2 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_23 PF13476.1 EIW74290.1 - 0.0089 16.3 0.3 0.053 13.8 0.2 2.3 1 1 0 1 1 1 1 AAA domain Annexin PF00191.15 EIW74290.1 - 0.0098 15.7 0.2 0.094 12.6 0.1 2.5 2 0 0 2 2 2 1 Annexin T2SE PF00437.15 EIW74290.1 - 0.01 14.7 0.0 0.018 13.9 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Ras PF00071.17 EIW74290.1 - 0.019 14.3 0.4 1.2 8.5 0.0 2.4 2 0 0 2 2 2 0 Ras family ABC_tran PF00005.22 EIW74290.1 - 0.029 14.6 0.0 0.09 13.0 0.0 1.9 1 0 0 1 1 1 0 ABC transporter AIG1 PF04548.11 EIW74290.1 - 0.036 13.1 0.1 0.41 9.7 0.0 2.2 2 0 0 2 2 2 0 AIG1 family Miro PF08477.8 EIW74290.1 - 0.039 14.4 0.0 2.3 8.7 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 EIW74290.1 - 0.046 13.8 0.0 0.24 11.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EIW74290.1 - 0.051 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B LEDGF PF11467.3 EIW74290.1 - 0.056 13.1 0.0 12 5.6 0.0 2.9 2 0 0 2 2 2 0 Lens epithelium-derived growth factor (LEDGF) FtsK_SpoIIIE PF01580.13 EIW74290.1 - 0.076 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 EIW74290.1 - 0.099 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Terpene_synth_C PF03936.11 EIW74291.1 - 3.5e-06 26.4 0.0 5e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Dynamin_N PF00350.18 EIW74292.1 - 3.1e-13 49.8 0.0 2.7e-12 46.8 0.0 2.6 2 1 0 2 2 2 1 Dynamin family AAA_16 PF13191.1 EIW74292.1 - 3.2e-07 30.5 4.9 5.9e-07 29.6 0.0 3.4 3 1 0 3 3 3 1 AAA ATPase domain MMR_HSR1 PF01926.18 EIW74292.1 - 3.2e-05 23.8 0.0 0.29 11.0 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase DUF258 PF03193.11 EIW74292.1 - 0.00024 20.3 0.0 0.0012 18.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EIW74292.1 - 0.0011 18.4 0.8 0.0035 16.8 0.2 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.7 EIW74292.1 - 0.0012 18.5 0.2 0.009 15.6 0.0 2.3 2 0 0 2 2 2 1 NACHT domain ABC_tran PF00005.22 EIW74292.1 - 0.0015 18.8 0.1 0.024 14.9 0.0 2.8 3 1 0 3 3 2 1 ABC transporter Herpes_Helicase PF02689.9 EIW74292.1 - 0.0015 16.3 0.0 0.0025 15.6 0.0 1.2 1 0 0 1 1 1 1 Helicase T2SE PF00437.15 EIW74292.1 - 0.0071 15.2 4.5 0.019 13.8 0.1 2.8 3 1 0 3 3 3 1 Type II/IV secretion system protein Septin PF00735.13 EIW74292.1 - 0.012 14.6 0.0 0.03 13.3 0.0 1.6 1 0 0 1 1 1 0 Septin Miro PF08477.8 EIW74292.1 - 0.017 15.5 0.5 1.4 9.4 0.0 3.1 2 1 1 3 3 3 0 Miro-like protein cobW PF02492.14 EIW74292.1 - 0.043 13.2 0.2 0.18 11.2 0.1 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EIW74292.1 - 0.048 13.8 0.2 0.76 9.9 0.0 3.0 3 0 0 3 3 2 0 AAA domain AAA_19 PF13245.1 EIW74292.1 - 0.05 13.3 0.1 0.24 11.1 0.1 2.2 1 0 0 1 1 1 0 Part of AAA domain AAA_23 PF13476.1 EIW74292.1 - 0.062 13.6 3.5 4.5 7.5 0.0 3.5 3 1 0 3 3 3 0 AAA domain MCM_N PF14551.1 EIW74292.1 - 0.07 13.6 3.0 2.7 8.4 0.0 3.0 2 1 0 2 2 2 0 MCM N-terminal domain AAA_17 PF13207.1 EIW74292.1 - 0.12 13.2 0.1 1.2 9.9 0.0 2.8 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 EIW74293.1 - 1.2e-07 31.0 0.2 1.5e-07 30.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EIW74293.1 - 6.6e-07 29.2 0.5 1.3e-06 28.3 0.4 1.4 1 0 0 1 1 1 1 Dynamin family AIG1 PF04548.11 EIW74293.1 - 2.8e-05 23.3 0.0 4.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 EIW74293.1 - 0.00057 19.8 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EIW74293.1 - 0.0009 19.2 1.0 0.024 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 EIW74293.1 - 0.0012 19.1 0.1 0.0018 18.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter Septin PF00735.13 EIW74293.1 - 0.002 17.2 0.1 0.0028 16.7 0.0 1.2 1 0 0 1 1 1 1 Septin NACHT PF05729.7 EIW74293.1 - 0.0042 16.7 0.0 0.0077 15.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_10 PF12846.2 EIW74293.1 - 0.0057 16.1 0.0 0.0079 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain KaiC PF06745.8 EIW74293.1 - 0.0061 15.7 0.3 0.016 14.3 0.1 1.7 2 0 0 2 2 2 1 KaiC FeoB_N PF02421.13 EIW74293.1 - 0.011 14.9 0.0 0.017 14.3 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B Miro PF08477.8 EIW74293.1 - 0.013 16.0 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein AAA_30 PF13604.1 EIW74293.1 - 0.022 14.3 0.0 0.03 13.9 0.0 1.1 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EIW74293.1 - 0.033 13.6 0.2 0.079 12.4 0.1 1.5 1 1 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 EIW74293.1 - 0.049 13.1 0.5 0.092 12.2 0.4 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EIW74293.1 - 0.056 12.8 0.0 0.093 12.1 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Guanylate_kin PF00625.16 EIW74293.1 - 0.14 11.5 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Guanylate kinase AAA_25 PF13481.1 EIW74293.1 - 0.15 11.4 0.2 0.26 10.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain Fungal_trans PF04082.13 EIW74294.1 - 5.9e-16 58.1 2.2 1.3e-15 56.9 1.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain SR-25 PF10500.4 EIW74294.1 - 8 5.8 7.6 13 5.1 5.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PBP1_TM PF14812.1 EIW74295.1 - 0.015 15.5 0.1 0.037 14.3 0.1 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal IBR PF01485.16 EIW74296.1 - 2.4e-12 46.5 31.2 1.7e-07 30.9 1.5 4.3 4 1 1 5 5 5 2 IBR domain zf-C3HC4_4 PF15227.1 EIW74296.1 - 9e-08 31.8 6.3 9e-08 31.8 4.4 4.4 4 1 0 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EIW74296.1 - 1.5e-06 28.1 5.6 1.5e-06 28.1 3.9 3.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIW74296.1 - 1.8e-06 27.5 1.5 1.8e-06 27.5 1.1 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EIW74296.1 - 3.7e-06 26.4 5.1 3.7e-06 26.4 3.5 4.1 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW74296.1 - 3.1e-05 23.6 6.0 3.1e-05 23.6 4.1 3.8 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIW74296.1 - 3.6e-05 23.3 4.2 3.6e-05 23.3 2.9 3.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW74296.1 - 0.013 15.2 5.3 0.013 15.2 3.7 3.9 3 1 0 3 3 3 0 zinc-RING finger domain IBR PF01485.16 EIW74297.1 - 3.2e-07 30.1 4.3 3.2e-07 30.1 3.0 3.8 3 1 0 3 3 3 1 IBR domain zf-C3HC4_4 PF15227.1 EIW74297.1 - 4.2e-06 26.5 2.7 4.2e-06 26.5 1.9 3.8 3 1 1 4 4 4 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EIW74297.1 - 1.9e-05 24.5 2.8 1.9e-05 24.5 1.9 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW74297.1 - 3.6e-05 23.3 1.3 3.6e-05 23.3 0.9 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW74297.1 - 0.00019 21.2 3.0 0.00019 21.2 2.1 3.4 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.1 EIW74297.1 - 0.00045 19.8 2.5 0.00045 19.8 1.7 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EIW74297.1 - 0.0066 16.0 1.9 0.0066 16.0 1.3 3.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Coronavirus_5 PF05528.6 EIW74297.1 - 0.054 13.3 0.5 0.054 13.3 0.4 2.9 3 0 0 3 3 3 0 Coronavirus gene 5 protein SPC12 PF06645.8 EIW74298.1 - 1.2e-21 76.3 0.1 1.3e-21 76.2 0.0 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF1515 PF07439.6 EIW74298.1 - 0.031 14.1 0.2 0.037 13.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Pkinase PF00069.20 EIW74299.1 - 1.7e-69 233.8 0.0 2.6e-69 233.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW74299.1 - 2.4e-36 125.1 0.0 3.9e-36 124.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EIW74299.1 - 9.6e-12 44.1 0.0 1.6e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 EIW74299.1 - 2e-06 27.0 0.2 3.6e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW74299.1 - 1.7e-05 24.6 0.4 0.033 13.9 0.0 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW74299.1 - 0.0015 17.5 0.0 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like WaaY PF06176.6 EIW74299.1 - 0.0048 16.1 0.4 0.0091 15.2 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide core biosynthesis protein (WaaY) YrbL-PhoP_reg PF10707.4 EIW74299.1 - 0.25 10.6 0.0 0.63 9.3 0.0 1.6 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Dynamin_N PF00350.18 EIW74300.1 - 4.4e-14 52.6 2.2 7.4e-13 48.6 0.0 3.3 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EIW74300.1 - 3.6e-07 30.1 0.2 1.2e-05 25.2 0.0 3.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EIW74300.1 - 7.3e-05 22.8 4.6 0.00018 21.5 0.0 3.4 3 2 0 3 3 3 1 AAA ATPase domain GTP_EFTU PF00009.22 EIW74300.1 - 0.00045 19.6 0.1 0.0029 17.0 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EIW74300.1 - 0.002 18.4 0.3 0.011 16.0 0.0 2.5 3 0 0 3 3 3 1 ABC transporter DUF258 PF03193.11 EIW74300.1 - 0.002 17.3 0.3 0.0082 15.3 0.0 2.1 2 1 1 3 3 3 1 Protein of unknown function, DUF258 NACHT PF05729.7 EIW74300.1 - 0.0034 17.0 0.2 0.011 15.3 0.1 2.0 2 0 0 2 2 2 1 NACHT domain Septin PF00735.13 EIW74300.1 - 0.0037 16.3 0.2 0.012 14.5 0.0 1.9 2 0 0 2 2 2 1 Septin AAA_24 PF13479.1 EIW74300.1 - 0.0086 15.6 0.2 1.5 8.3 0.0 2.9 2 1 1 3 3 3 1 AAA domain SRPRB PF09439.5 EIW74300.1 - 0.013 14.7 0.0 0.058 12.6 0.0 2.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 EIW74300.1 - 0.032 14.7 0.4 0.7 10.4 0.0 3.0 2 1 1 3 3 3 0 Miro-like protein cobW PF02492.14 EIW74300.1 - 0.051 13.0 0.0 0.19 11.1 0.0 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.11 EIW74300.1 - 0.23 10.5 4.7 0.3 10.1 0.0 3.3 4 0 0 4 4 4 0 AIG1 family SPOB_a PF14689.1 EIW74300.1 - 0.37 10.3 3.0 16 5.1 0.2 3.6 2 0 0 2 2 2 0 Sensor_kinase_SpoOB-type, alpha-helical domain AAA_23 PF13476.1 EIW74300.1 - 3 8.1 0.0 3 8.1 0.0 4.2 2 2 1 3 3 2 0 AAA domain LRR_4 PF12799.2 EIW74301.1 - 0.71 9.5 5.8 9 6.0 0.8 3.9 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) DUF2235 PF09994.4 EIW74303.1 - 1.6e-54 185.1 0.1 9.7e-54 182.5 0.1 1.9 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF3850 PF12961.2 EIW74303.1 - 0.052 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3850) SLD3 PF08639.5 EIW74304.1 - 9.2e-10 37.7 19.3 5.2e-08 31.9 11.0 2.4 2 1 0 2 2 2 2 DNA replication regulator SLD3 NAGLU PF05089.7 EIW74305.1 - 5.8e-114 380.3 0.9 8.2e-114 379.8 0.7 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 EIW74305.1 - 4.3e-48 164.0 0.2 6.3e-48 163.4 0.1 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 EIW74305.1 - 1.2e-13 50.5 0.0 2.6e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain F-box-like PF12937.2 EIW74306.1 - 0.016 14.8 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 F-box-like FAD_binding_4 PF01565.18 EIW74307.1 - 3.4e-17 62.2 3.5 5.9e-17 61.4 2.0 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EIW74307.1 - 1.7e-07 30.9 0.1 3.5e-07 30.0 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like F-box-like PF12937.2 EIW74308.1 - 4.8e-05 22.9 0.3 0.00012 21.7 0.0 1.8 2 0 0 2 2 2 1 F-box-like RNase_H PF00075.19 EIW74310.1 - 0.0011 19.3 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 RNase H Glyco_hydro_28 PF00295.12 EIW74312.1 - 1.6e-54 185.0 11.5 2.1e-54 184.6 8.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Condensin2nSMC PF12422.3 EIW74314.1 - 0.01 15.5 0.1 0.047 13.4 0.0 1.9 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit Vac_Fusion PF02346.11 EIW74314.1 - 0.23 10.9 4.5 0.25 10.7 0.1 3.2 4 0 0 4 4 4 0 Chordopoxvirus fusion protein TFIIF_alpha PF05793.7 EIW74317.1 - 7.6 4.7 35.2 17 3.6 24.4 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ChAPs PF09295.5 EIW74318.1 - 2.1e-147 491.0 0.0 4.3e-146 486.7 0.0 2.0 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_2 PF07719.12 EIW74318.1 - 3.6e-08 32.7 3.1 0.12 12.3 0.2 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIW74318.1 - 4.4e-08 32.6 1.8 0.032 13.8 0.1 3.7 3 0 0 3 3 3 3 TPR repeat TPR_19 PF14559.1 EIW74318.1 - 6.4e-08 32.8 0.4 8e-06 26.1 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIW74318.1 - 0.00016 21.1 1.7 0.2 11.5 0.0 4.5 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIW74318.1 - 0.00038 20.8 8.7 5.9 7.8 0.1 6.7 4 2 4 8 8 7 1 Tetratricopeptide repeat TPR_15 PF13429.1 EIW74318.1 - 0.00056 19.0 5.0 0.23 10.5 0.4 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIW74318.1 - 0.0063 16.4 4.7 2.2 8.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIW74318.1 - 0.0063 17.1 1.6 2.5 8.8 0.0 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.3 EIW74318.1 - 0.022 13.5 0.6 2.1 7.0 0.0 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 EIW74318.1 - 0.045 14.2 0.9 70 4.2 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 EIW74318.1 - 0.057 13.6 0.3 63 4.1 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIW74318.1 - 0.89 9.2 2.9 15 5.4 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2046 PF09755.4 EIW74319.1 - 1.1e-10 40.9 10.0 1.1e-10 40.9 6.9 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein H4 (DUF2046) SYCE1 PF15233.1 EIW74319.1 - 9.1e-05 22.3 1.9 0.0009 19.1 0.6 2.2 2 0 0 2 2 2 1 Synaptonemal complex central element protein 1 TSA PF03249.8 EIW74319.1 - 1.1 7.6 5.8 1.6 7.1 4.0 1.1 1 0 0 1 1 1 0 Type specific antigen TORC_N PF12884.2 EIW74319.1 - 6.6 7.3 9.1 2.7 8.5 4.1 2.0 2 0 0 2 2 2 0 Transducer of regulated CREB activity, N terminus HSP20 PF00011.16 EIW74320.1 - 2.4e-09 36.9 0.0 3.3e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family BTB PF00651.26 EIW74321.1 - 8.1e-08 32.2 0.0 1.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Transp_cyt_pur PF02133.10 EIW74322.1 - 1.3e-30 106.3 37.6 3.4e-30 104.9 26.1 1.7 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin PAF-AH_p_II PF03403.8 EIW74323.1 - 3.2e-50 170.4 0.0 4.2e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EIW74323.1 - 1.9e-14 53.6 0.1 4.3e-14 52.4 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW74323.1 - 4e-09 36.6 0.1 1.1e-08 35.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EIW74323.1 - 7e-07 28.3 0.0 9.7e-05 21.3 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Chlorophyllase PF07224.6 EIW74323.1 - 2.6e-05 23.1 0.0 0.00057 18.7 0.0 2.1 2 0 0 2 2 2 1 Chlorophyllase Hydrolase_4 PF12146.3 EIW74323.1 - 0.0079 16.0 0.0 0.024 14.4 0.0 1.7 2 0 0 2 2 2 1 Putative lysophospholipase AXE1 PF05448.7 EIW74323.1 - 0.031 12.7 0.0 3.8 5.9 0.0 2.2 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) SH3_6 PF12913.2 EIW74323.1 - 0.039 13.1 0.0 11 5.3 0.0 2.6 2 0 0 2 2 2 0 SH3 domain of the SH3b1 type Ion_trans_2 PF07885.11 EIW74327.1 - 6.3e-28 96.3 40.7 1.2e-15 56.9 11.8 2.9 3 0 0 3 3 3 2 Ion channel Serglycin PF04360.7 EIW74327.1 - 0.0054 16.4 0.7 0.22 11.2 0.2 2.5 2 0 0 2 2 2 1 Serglycin DUF3430 PF11912.3 EIW74328.1 - 0.0007 19.4 0.1 0.00081 19.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF4072 PF13284.1 EIW74328.1 - 0.041 14.0 0.3 0.26 11.4 0.0 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4072) BTB PF00651.26 EIW74329.1 - 3.7e-14 52.6 0.0 4.8e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain HrpB1_HrpK PF09613.5 EIW74329.1 - 0.0081 15.6 1.0 0.92 8.9 0.1 2.4 2 1 0 2 2 2 2 Bacterial type III secretion protein (HrpB1_HrpK) Carboxyl_trans PF01039.17 EIW74330.1 - 1.5e-76 257.7 0.1 1.1e-75 254.9 0.0 1.8 1 1 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EIW74331.1 - 1.5e-54 184.4 0.0 2.7e-54 183.6 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_4 PF13535.1 EIW74331.1 - 1.9e-24 86.4 0.1 4.1e-24 85.3 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_carb_C PF02785.14 EIW74331.1 - 7.1e-23 80.6 0.0 2.1e-22 79.1 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATPgrasp_Ter PF15632.1 EIW74331.1 - 1.4e-14 53.5 0.0 8.1e-10 37.9 0.0 2.1 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_chain PF00289.17 EIW74331.1 - 4.5e-13 49.2 0.1 5.7e-12 45.7 0.0 2.8 2 1 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Dala_Dala_lig_C PF07478.8 EIW74331.1 - 1.3e-09 37.8 0.0 2.3e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EIW74331.1 - 2.5e-09 36.6 0.0 4.2e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EIW74331.1 - 1.2e-05 25.2 0.0 2.2e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EIW74331.1 - 7.1e-05 22.3 0.3 0.0002 20.9 0.2 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme RimK PF08443.6 EIW74331.1 - 0.00013 21.4 0.0 0.00031 20.2 0.0 1.5 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_2 PF08442.5 EIW74331.1 - 0.01 15.2 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Pribosyltran PF00156.22 EIW74332.1 - 9.6e-14 51.1 0.1 1.5e-13 50.5 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain AA_kinase PF00696.23 EIW74336.1 - 8.8e-34 117.1 0.1 2.5e-32 112.3 0.1 2.2 1 1 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 EIW74336.1 - 5.8e-13 48.0 0.6 8.3e-06 25.1 0.0 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 EIW74336.1 - 1.3e-09 37.4 3.7 3.4e-07 29.6 0.2 3.6 4 0 0 4 4 4 2 ACT domain G-alpha PF00503.15 EIW74338.1 - 1.5e-144 481.5 0.0 1.8e-144 481.2 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIW74338.1 - 6.3e-10 38.5 0.0 6.6e-07 28.7 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 EIW74338.1 - 0.0022 17.5 0.0 0.005 16.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EIW74338.1 - 0.086 12.2 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EIW74338.1 - 0.092 12.8 0.0 0.24 11.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIW74338.1 - 0.092 13.0 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DAP3 PF10236.4 EIW74338.1 - 0.12 11.3 0.1 0.2 10.5 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Abhydrolase_6 PF12697.2 EIW74340.1 - 1.1e-27 97.4 0.4 1.3e-27 97.1 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW74340.1 - 6.9e-18 65.0 0.3 2e-17 63.5 0.2 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW74340.1 - 1.6e-08 34.3 0.4 1.3e-07 31.5 0.3 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EIW74340.1 - 3.9e-06 26.4 0.0 6.7e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 EIW74340.1 - 0.006 16.0 0.0 0.0086 15.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF2048 PF09752.4 EIW74340.1 - 0.028 13.3 0.0 0.034 13.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Lipase_3 PF01764.20 EIW74340.1 - 0.086 12.4 0.0 0.18 11.4 0.0 1.5 1 1 0 1 1 1 0 Lipase (class 3) Peptidase_S9 PF00326.16 EIW74340.1 - 0.11 11.6 0.1 0.36 10.0 0.0 1.8 2 1 0 2 2 2 0 Prolyl oligopeptidase family AAA_12 PF13087.1 EIW74341.1 - 4.8e-43 146.8 0.0 6.9e-43 146.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIW74341.1 - 8.7e-32 110.5 0.0 4.1e-16 59.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EIW74341.1 - 8.5e-13 48.3 0.0 1.2e-11 44.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW74341.1 - 4.5e-11 42.3 0.5 1.4e-10 40.7 0.3 1.9 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 EIW74341.1 - 1.1e-06 28.3 0.0 0.092 12.2 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.16 EIW74341.1 - 4.8e-06 26.0 0.0 0.00069 19.0 0.0 2.4 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain PhoH PF02562.11 EIW74341.1 - 0.00014 21.1 0.0 0.24 10.6 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_16 PF13191.1 EIW74341.1 - 0.00078 19.4 0.0 0.0034 17.3 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EIW74341.1 - 0.0015 18.6 0.0 0.044 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EIW74341.1 - 0.0022 17.1 0.0 0.0061 15.7 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 EIW74341.1 - 0.012 15.0 0.0 0.2 11.0 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain UvrD_C_2 PF13538.1 EIW74341.1 - 0.013 15.6 0.0 0.032 14.3 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA PF00004.24 EIW74341.1 - 0.013 15.6 0.0 0.032 14.4 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIW74341.1 - 0.022 14.5 0.0 0.069 12.8 0.0 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) ResIII PF04851.10 EIW74341.1 - 0.032 14.0 0.0 0.32 10.8 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 EIW74341.1 - 0.053 13.1 0.1 0.28 10.8 0.1 2.2 1 1 0 1 1 1 0 Helicase ArgK PF03308.11 EIW74341.1 - 0.076 11.7 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_24 PF13479.1 EIW74341.1 - 0.081 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EIW74341.1 - 0.16 11.4 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.1 EIW74341.1 - 0.21 12.3 0.9 1.7 9.5 0.0 2.8 4 0 0 4 4 3 0 AAA domain AAA_12 PF13087.1 EIW74342.1 - 1e-41 142.5 0.0 1.6e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIW74342.1 - 1.3e-31 109.9 0.0 1.1e-16 61.1 0.0 2.3 1 1 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EIW74342.1 - 2.5e-10 40.2 0.0 1.8e-09 37.4 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIW74342.1 - 1.1e-09 37.8 0.0 2.7e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain PhoH PF02562.11 EIW74342.1 - 5.7e-05 22.4 0.0 0.11 11.7 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein Viral_helicase1 PF01443.13 EIW74342.1 - 8.8e-05 22.1 0.0 0.17 11.3 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EIW74342.1 - 0.00015 21.9 0.0 0.0021 18.2 0.0 2.2 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.16 EIW74342.1 - 0.00035 19.9 0.0 0.47 9.7 0.0 2.2 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_5 PF07728.9 EIW74342.1 - 0.0011 18.7 0.0 0.77 9.4 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIW74342.1 - 0.0018 18.2 0.0 0.0034 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 EIW74342.1 - 0.0028 16.8 0.0 0.0056 15.8 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI UvrD_C_2 PF13538.1 EIW74342.1 - 0.0081 16.2 0.0 0.023 14.8 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.1 EIW74342.1 - 0.019 14.4 0.0 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA PF00004.24 EIW74342.1 - 0.029 14.5 0.0 0.075 13.2 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EIW74342.1 - 0.035 13.5 0.0 0.077 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain AAA_25 PF13481.1 EIW74342.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Helicase_RecD PF05127.9 EIW74342.1 - 0.18 11.3 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_24 PF13479.1 EIW74342.1 - 0.18 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1368 PF07112.6 EIW74342.1 - 0.41 9.1 0.0 0.65 8.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1368) Mg_trans_NIPA PF05653.9 EIW74343.1 - 5.8e-95 317.7 10.3 7.2e-95 317.3 7.2 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EIW74343.1 - 6.4e-06 26.3 0.3 6.4e-06 26.3 0.2 3.3 2 1 1 3 3 3 1 Multidrug resistance efflux transporter DUF4611 PF15387.1 EIW74343.1 - 0.81 9.8 5.4 1.4 9.1 3.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 EIW74343.1 - 1.1 8.7 4.8 1.8 8.0 3.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin EamA PF00892.15 EIW74343.1 - 3.4 7.7 24.5 0.055 13.5 2.1 3.0 3 1 0 3 3 3 0 EamA-like transporter family LZ_Tnp_IS66 PF13007.2 EIW74343.1 - 4.9 7.8 8.6 24 5.6 5.9 1.9 1 1 0 1 1 1 0 Transposase C of IS166 homeodomain Zn_clus PF00172.13 EIW74344.1 - 2.3e-05 24.1 8.8 4e-05 23.4 6.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_S28 PF05577.7 EIW74346.1 - 1.2e-52 179.0 2.7 2.1e-52 178.1 1.8 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 EIW74346.1 - 6.1e-07 28.8 0.2 1.3e-06 27.8 0.2 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hepar_II_III PF07940.8 EIW74347.1 - 1.7e-07 31.1 0.3 3.1e-07 30.3 0.2 1.4 1 0 0 1 1 1 1 Heparinase II/III-like protein DUF1628 PF07790.6 EIW74347.1 - 0.4 11.4 3.4 0.46 11.2 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1628) Metallophos PF00149.23 EIW74349.1 - 2.9e-42 144.3 0.5 4.1e-42 143.8 0.3 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.23 EIW74350.1 - 1.4e-40 138.8 0.2 2.3e-40 138.1 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase UNC-50 PF05216.8 EIW74352.1 - 2e-84 282.4 10.2 2.2e-84 282.2 7.0 1.0 1 0 0 1 1 1 1 UNC-50 family MgtE PF01769.11 EIW74352.1 - 0.034 14.4 1.3 0.034 14.4 0.9 1.7 2 1 0 2 2 2 0 Divalent cation transporter DUF3169 PF11368.3 EIW74352.1 - 0.035 13.3 0.1 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) YebO PF13974.1 EIW74352.1 - 0.12 12.1 0.3 0.28 11.0 0.2 1.5 1 0 0 1 1 1 0 YebO-like protein LRR_6 PF13516.1 EIW74354.1 - 2.4 8.5 5.9 28 5.1 0.0 5.1 6 0 0 6 6 6 0 Leucine Rich repeat EBP PF05241.7 EIW74355.1 - 0.032 13.2 0.2 0.069 12.1 0.0 1.6 1 1 1 2 2 2 0 Emopamil binding protein XPG_I PF00867.13 EIW74356.1 - 2e-18 66.1 0.0 3.6e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 EIW74356.1 - 0.031 13.7 0.0 0.044 13.2 0.0 1.2 1 0 0 1 1 1 0 XPG domain containing Peptidase_M24 PF00557.19 EIW74358.1 - 1e-46 159.1 0.0 1.7e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EIW74358.1 - 2.2e-29 102.5 0.1 6.5e-22 78.4 0.0 2.7 2 1 1 3 3 3 2 Creatinase/Prolidase N-terminal domain ABC_tran PF00005.22 EIW74360.1 - 5.9e-27 94.6 0.0 1.2e-26 93.5 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EIW74360.1 - 6.2e-06 25.5 0.7 0.00021 20.5 0.5 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain ABC_membrane PF00664.18 EIW74360.1 - 3.3e-05 23.4 1.8 4.9e-05 22.8 1.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region T2SE PF00437.15 EIW74360.1 - 0.00051 19.0 0.0 0.00088 18.2 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 EIW74360.1 - 0.0016 18.4 0.0 0.0034 17.3 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.12 EIW74360.1 - 0.0018 18.1 0.2 0.004 17.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_21 PF13304.1 EIW74360.1 - 0.0032 17.4 0.0 1 9.2 0.0 2.2 1 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EIW74360.1 - 0.0055 16.1 0.0 0.05 13.0 0.0 2.1 2 0 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 EIW74360.1 - 0.014 14.7 0.0 0.041 13.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EIW74360.1 - 0.017 15.2 0.6 0.36 10.9 0.3 2.5 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EIW74360.1 - 0.048 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 EIW74360.1 - 0.064 12.7 0.1 0.16 11.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EIW74360.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 EIW74360.1 - 0.12 12.0 0.1 0.35 10.5 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EIW74360.1 - 0.15 11.6 0.2 1.5 8.3 0.1 2.4 1 1 1 2 2 2 0 AAA domain Yip1 PF04893.12 EIW74360.1 - 3.8 6.9 15.3 12 5.3 10.7 1.8 1 1 0 1 1 1 0 Yip1 domain ABC_tran PF00005.22 EIW74362.1 - 4.9e-11 43.0 0.1 5.3e-10 39.7 0.0 2.4 2 1 0 2 2 2 1 ABC transporter cobW PF02492.14 EIW74362.1 - 0.0028 17.1 0.3 0.18 11.2 0.2 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 EIW74362.1 - 0.053 12.9 0.6 0.18 11.2 0.4 1.8 1 1 0 1 1 1 0 AAA domain DUF4396 PF14342.1 EIW74362.1 - 0.082 13.0 1.5 0.15 12.1 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4396) SMC_N PF02463.14 EIW74362.1 - 0.091 11.9 0.1 0.73 9.0 0.1 2.1 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain T2SE PF00437.15 EIW74362.1 - 0.092 11.6 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein UPF0079 PF02367.12 EIW74362.1 - 0.13 11.9 0.1 0.3 10.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Dimer_Tnp_hAT PF05699.9 EIW74363.1 - 3e-07 29.9 0.0 3.1e-07 29.9 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region LT-IIB PF06453.6 EIW74363.1 - 0.11 12.1 0.2 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) DUF4653 PF15546.1 EIW74363.1 - 0.14 11.4 0.1 0.15 11.3 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) DUF2670 PF10875.3 EIW74365.1 - 0.17 11.9 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) PIGA PF08288.7 EIW74367.1 - 5.1e-38 129.3 0.2 1.3e-37 128.0 0.1 1.7 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EIW74367.1 - 4.8e-27 94.4 0.0 7.4e-27 93.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EIW74367.1 - 3.7e-13 49.7 0.2 1.6e-12 47.7 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EIW74367.1 - 8.9e-13 48.3 0.8 2.3e-12 46.9 0.6 1.8 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EIW74367.1 - 6.6e-11 42.6 3.2 6.6e-11 42.6 2.2 2.2 3 0 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EIW74367.1 - 9.3e-06 25.8 0.1 2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF4229 PF14012.1 EIW74368.1 - 0.41 10.5 0.1 0.41 10.5 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4229) DUF4131 PF13567.1 EIW74368.1 - 3.4 7.0 10.2 1.1 8.5 0.9 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Oxysterol_BP PF01237.13 EIW74369.1 - 3.6e-50 170.4 0.0 1.3e-37 129.0 0.0 2.2 2 1 0 2 2 2 2 Oxysterol-binding protein Herpes_gE PF02480.11 EIW74370.1 - 0.016 13.4 0.0 0.028 12.6 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E CorA PF01544.13 EIW74371.1 - 1.6e-09 37.2 1.5 2.9e-09 36.3 1.0 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3660 PF12398.3 EIW74371.1 - 0.066 13.0 2.5 0.15 11.9 1.7 1.5 1 0 0 1 1 1 0 Receptor serine/threonine kinase SseB_C PF14581.1 EIW74371.1 - 0.075 12.8 0.4 0.16 11.7 0.2 1.5 1 0 0 1 1 1 0 SseB protein C-terminal domain AAA PF00004.24 EIW74373.1 - 2.5e-44 150.6 0.0 4.6e-44 149.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EIW74373.1 - 3.1e-08 33.7 0.0 6.6e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EIW74373.1 - 1.3e-06 28.2 0.0 6.3e-06 25.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIW74373.1 - 3.6e-06 27.0 0.5 1.8e-05 24.8 0.0 2.2 2 1 1 3 3 2 1 AAA ATPase domain AAA_22 PF13401.1 EIW74373.1 - 5.6e-06 26.5 0.3 0.00031 20.9 0.0 2.7 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EIW74373.1 - 5.3e-05 22.8 0.1 0.00015 21.4 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EIW74373.1 - 6.4e-05 23.7 0.1 0.00016 22.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EIW74373.1 - 9.5e-05 21.5 0.0 0.00017 20.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EIW74373.1 - 0.00035 20.0 0.0 0.00076 18.9 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EIW74373.1 - 0.00088 18.0 0.0 0.0016 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EIW74373.1 - 0.0015 18.4 0.0 0.0032 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EIW74373.1 - 0.0021 17.9 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIW74373.1 - 0.0021 17.1 0.0 0.0045 16.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin DUF2072 PF09845.4 EIW74373.1 - 0.0032 17.3 0.1 0.0069 16.3 0.1 1.5 1 0 0 1 1 1 1 Zn-ribbon containing protein (DUF2072) AAA_28 PF13521.1 EIW74373.1 - 0.0037 17.2 0.3 0.007 16.3 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_3 PF07726.6 EIW74373.1 - 0.0039 16.8 0.0 0.0078 15.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EIW74373.1 - 0.0039 16.4 0.0 0.063 12.4 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 EIW74373.1 - 0.0065 15.6 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EIW74373.1 - 0.0079 16.5 0.0 0.032 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EIW74373.1 - 0.016 14.3 0.0 0.033 13.2 0.0 1.5 1 0 0 1 1 1 0 KaiC Sigma54_activat PF00158.21 EIW74373.1 - 0.018 14.5 0.0 0.085 12.3 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 EIW74373.1 - 0.02 14.2 0.1 0.082 12.2 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EIW74373.1 - 0.021 14.3 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EIW74373.1 - 0.022 13.6 0.0 0.045 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EIW74373.1 - 0.035 14.2 0.0 0.066 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.1 EIW74373.1 - 0.043 13.8 0.0 0.15 12.1 0.0 2.0 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EIW74373.1 - 0.051 12.4 0.0 0.089 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.7 EIW74373.1 - 0.067 12.8 0.0 0.55 9.8 0.0 2.1 1 1 1 2 2 2 0 NACHT domain cobW PF02492.14 EIW74373.1 - 0.078 12.4 0.3 13 5.1 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 EIW74373.1 - 0.098 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_12 PF13087.1 EIW74374.1 - 1.4e-44 151.8 0.0 2.1e-44 151.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIW74374.1 - 2.8e-28 99.0 0.0 1.8e-13 50.6 0.0 2.6 1 1 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EIW74374.1 - 5.1e-12 45.7 0.0 1.6e-11 44.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW74374.1 - 3.7e-09 36.2 0.1 8.9e-09 34.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain PhoH PF02562.11 EIW74374.1 - 0.00049 19.4 0.0 0.65 9.1 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein UvrD-helicase PF00580.16 EIW74374.1 - 0.0018 17.6 0.0 1.3 8.2 0.0 2.4 2 0 0 2 2 2 2 UvrD/REP helicase N-terminal domain AAA_22 PF13401.1 EIW74374.1 - 0.01 15.9 0.0 0.11 12.5 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EIW74374.1 - 0.018 14.9 0.0 9.1 6.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain UvrD_C PF13361.1 EIW74374.1 - 0.03 13.7 0.0 3.8 6.8 0.0 2.2 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_10 PF12846.2 EIW74374.1 - 0.064 12.6 0.0 0.14 11.5 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain AAA PF00004.24 EIW74374.1 - 0.092 12.9 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EIW74374.1 - 0.1 11.5 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.10 EIW74374.1 - 0.19 11.5 0.0 1.1 9.0 0.0 2.2 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 EIW74375.1 - 6.8e-48 162.4 0.0 1.4e-28 99.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIW74375.1 - 4.1e-36 124.8 17.7 2.8e-19 69.5 6.2 2.6 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EIW74375.1 - 1.4e-09 37.5 0.0 0.0012 18.1 0.3 3.3 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EIW74375.1 - 3.2e-06 26.6 0.0 0.085 12.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EIW74375.1 - 0.00029 20.9 0.0 2.9 7.7 0.0 3.4 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 EIW74375.1 - 0.00086 18.2 0.1 0.023 13.6 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.2 EIW74375.1 - 0.00089 18.7 0.7 0.094 12.1 0.0 2.5 2 1 0 2 2 2 1 AAA-like domain FtsK_SpoIIIE PF01580.13 EIW74375.1 - 0.00097 18.6 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_29 PF13555.1 EIW74375.1 - 0.0012 18.3 0.6 0.16 11.5 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EIW74375.1 - 0.0016 18.5 1.6 2.1 8.4 0.3 3.4 2 1 0 2 2 2 1 AAA domain DUF87 PF01935.12 EIW74375.1 - 0.0049 16.7 0.1 0.012 15.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_23 PF13476.1 EIW74375.1 - 0.038 14.3 0.8 9.2 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EIW74375.1 - 0.054 12.3 0.0 1.9 7.2 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain UPF0079 PF02367.12 EIW74375.1 - 0.062 12.9 0.4 0.48 10.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 EIW74375.1 - 0.063 13.2 2.9 0.32 10.9 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain Peptidase_M23 PF01551.17 EIW74375.1 - 0.099 12.7 0.0 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Peptidase family M23 Miro PF08477.8 EIW74375.1 - 0.17 12.4 1.2 20 5.7 0.1 3.0 2 1 0 2 2 2 0 Miro-like protein DUF258 PF03193.11 EIW74375.1 - 0.23 10.6 0.0 23 4.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NACHT PF05729.7 EIW74375.1 - 0.28 10.8 1.4 19 4.9 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 EIW74375.1 - 0.41 10.9 3.0 2.3 8.5 0.3 2.9 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EIW74375.1 - 0.41 10.0 3.4 3 7.2 0.5 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Methyltransf_16 PF10294.4 EIW74376.1 - 0.00044 19.7 0.1 0.046 13.1 0.0 2.5 3 0 0 3 3 3 2 Putative methyltransferase S1-P1_nuclease PF02265.11 EIW74377.1 - 2e-43 148.8 0.0 6.6e-39 134.0 0.0 3.2 3 1 0 3 3 3 3 S1/P1 Nuclease DUF2335 PF10097.4 EIW74379.1 - 0.0078 15.8 4.1 0.016 14.7 2.8 1.5 1 0 0 1 1 1 1 Predicted membrane protein (DUF2335) Baculo_PEP_C PF04513.7 EIW74379.1 - 0.22 11.3 2.6 1.9 8.2 0.6 2.1 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus AIG1 PF04548.11 EIW74379.1 - 1.6 7.7 4.7 2.5 7.1 3.2 1.2 1 0 0 1 1 1 0 AIG1 family FadA PF09403.5 EIW74379.1 - 1.8 8.5 6.9 0.15 12.0 1.3 1.8 1 1 1 2 2 2 0 Adhesion protein FadA DUF3829 PF12889.2 EIW74379.1 - 2.3 7.3 5.4 3.3 6.8 3.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF342 PF03961.8 EIW74379.1 - 3.2 6.0 4.7 3.7 5.8 2.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF3584 PF12128.3 EIW74379.1 - 4.7 4.4 19.0 7.1 3.8 13.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) UPF0184 PF03670.8 EIW74379.1 - 5.9 7.1 7.9 25 5.1 0.3 3.2 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0184) Sin3_corepress PF08295.7 EIW74380.1 - 3.4e-35 119.8 0.0 7.9e-35 118.6 0.0 1.6 1 0 0 1 1 1 1 Sin3 family co-repressor PAH PF02671.16 EIW74380.1 - 2.4e-29 100.6 0.0 6.4e-16 57.6 0.0 3.5 3 0 0 3 3 3 3 Paired amphipathic helix repeat Atrophin-1 PF03154.10 EIW74380.1 - 0.00043 18.6 11.7 0.00043 18.6 8.1 3.0 3 0 0 3 3 3 1 Atrophin-1 family NACHT PF05729.7 EIW74381.1 - 4.6e-11 42.6 0.0 1.7e-10 40.8 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EIW74381.1 - 1.8e-07 31.3 0.1 6.2e-07 29.5 0.1 1.7 1 1 1 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.10 EIW74381.1 - 2.1e-05 24.3 0.0 3.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 NTPase AAA_22 PF13401.1 EIW74381.1 - 0.00011 22.3 0.0 0.00043 20.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIW74381.1 - 0.00016 21.3 0.0 0.00049 19.7 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain ArgK PF03308.11 EIW74381.1 - 0.00033 19.5 0.1 0.00069 18.4 0.0 1.4 1 0 0 1 1 1 1 ArgK protein APS_kinase PF01583.15 EIW74381.1 - 0.00099 18.7 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.17 EIW74381.1 - 0.0018 18.4 0.0 0.0099 16.0 0.0 2.1 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.7 EIW74381.1 - 0.002 17.2 0.0 0.0033 16.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 EIW74381.1 - 0.0072 17.1 0.0 0.02 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EIW74381.1 - 0.015 15.4 0.0 0.03 14.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EIW74381.1 - 0.017 14.6 0.1 0.27 10.7 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EIW74381.1 - 0.022 15.0 0.0 0.039 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EIW74381.1 - 0.026 14.2 0.0 0.19 11.4 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase KTI12 PF08433.5 EIW74381.1 - 0.036 13.2 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.22 EIW74381.1 - 0.052 13.8 0.0 0.27 11.5 0.0 2.0 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.1 EIW74381.1 - 0.053 13.1 0.2 0.12 11.9 0.1 1.6 2 0 0 2 2 1 0 AAA domain TadE PF07811.7 EIW74381.1 - 0.065 13.1 0.5 1.1 9.2 0.0 2.9 3 0 0 3 3 3 0 TadE-like protein AAA_10 PF12846.2 EIW74381.1 - 0.068 12.5 0.1 0.45 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain DUF2075 PF09848.4 EIW74381.1 - 0.088 11.7 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EIW74381.1 - 0.11 11.3 0.0 0.24 10.1 0.0 1.6 2 0 0 2 2 2 0 NB-ARC domain AAA_33 PF13671.1 EIW74381.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EIW74381.1 - 0.14 12.2 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain GATase_3 PF07685.9 EIW74382.1 - 0.091 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain bZIP_1 PF00170.16 EIW74384.1 - 1.7e-06 27.9 4.7 2.1e-05 24.3 2.7 2.3 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EIW74384.1 - 1.8e-05 24.4 1.9 1.8e-05 24.4 1.3 3.2 2 1 1 3 3 3 2 Basic region leucine zipper DUF972 PF06156.8 EIW74384.1 - 0.1 12.9 0.1 0.34 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 EIW74384.1 - 0.17 10.2 0.1 0.23 9.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain bZIP_Maf PF03131.12 EIW74384.1 - 1.7 8.9 7.3 0.2 11.9 0.9 2.1 2 0 0 2 2 2 0 bZIP Maf transcription factor WD40 PF00400.27 EIW74387.1 - 6.2e-101 327.0 36.5 5.9e-15 54.4 0.2 8.9 7 1 1 8 8 8 8 WD domain, G-beta repeat PD40 PF07676.7 EIW74387.1 - 2e-12 46.4 4.4 11 5.8 0.0 8.6 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EIW74387.1 - 6e-12 44.4 0.8 0.04 12.0 0.0 4.8 2 2 2 4 4 4 4 Nucleoporin Nup120/160 eIF2A PF08662.6 EIW74387.1 - 1.4e-08 34.6 0.0 0.0017 18.1 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.1 EIW74387.1 - 5.1e-08 32.9 7.4 1.1 9.5 0.0 7.2 5 2 2 7 7 7 1 PQQ-like domain AAA_16 PF13191.1 EIW74387.1 - 3.5e-07 30.3 0.0 8.3e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Proteasome_A_N PF10584.4 EIW74387.1 - 2.6e-05 23.4 7.3 97 2.4 0.0 8.4 8 0 0 8 8 8 0 Proteasome subunit A N-terminal signature NB-ARC PF00931.17 EIW74387.1 - 3e-05 23.0 0.1 7.1e-05 21.8 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 EIW74387.1 - 3.5e-05 23.5 0.2 0.00014 21.5 0.1 2.0 1 1 0 1 1 1 1 NACHT domain Peptidase_S9_N PF02897.10 EIW74387.1 - 0.00035 19.2 0.1 3.6 6.0 0.0 4.4 2 2 2 4 4 4 1 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF2075 PF09848.4 EIW74387.1 - 0.0017 17.3 0.1 0.0051 15.8 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.15 EIW74387.1 - 0.0053 16.4 0.0 0.0095 15.6 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_30 PF13604.1 EIW74387.1 - 0.0055 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EIW74387.1 - 0.0065 16.6 0.0 0.036 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EIW74387.1 - 0.0068 16.6 0.1 0.032 14.4 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EIW74387.1 - 0.0089 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_17 PF13207.1 EIW74387.1 - 0.02 15.6 0.0 0.08 13.7 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.1 EIW74387.1 - 0.025 14.3 0.0 0.068 12.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 EIW74387.1 - 0.055 12.5 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.8 EIW74387.1 - 0.12 11.3 0.0 0.32 9.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 EIW74387.1 - 0.13 12.5 0.0 0.39 11.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EIW74387.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 NTPase OSTbeta PF15048.1 EIW74389.1 - 0.44 10.6 1.9 1.2 9.2 0.1 2.1 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein IF4E PF01652.13 EIW74391.1 - 4.5e-45 153.1 0.0 6.3e-45 152.6 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E CPSF_A PF03178.10 EIW74392.1 - 8.7e-74 248.4 0.0 1.3e-73 247.9 0.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region DUF362 PF04015.7 EIW74393.1 - 0.0065 15.9 0.0 0.025 14.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF362) Glyco_hydro_61 PF03443.9 EIW74395.1 - 1.4e-58 198.2 0.1 2e-58 197.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF983 PF06170.7 EIW74397.1 - 8.6 6.5 8.0 0.58 10.2 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF983) CbbQ_C PF08406.5 EIW74398.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 CbbQ/NirQ/NorQ C-terminal zf-XS PF03470.9 EIW74403.1 - 0.074 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 XS zinc finger domain DUF1814 PF08843.6 EIW74405.1 - 0.0004 20.2 0.4 0.00059 19.6 0.3 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) NTP_transf_2 PF01909.18 EIW74405.1 - 0.0081 16.4 0.0 0.015 15.6 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF2204 PF09970.4 EIW74405.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) DUF1814 PF08843.6 EIW74408.1 - 0.0016 18.3 0.0 0.0022 17.7 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase of unknown function (DUF1814) T4_deiodinase PF00837.12 EIW74408.1 - 0.25 10.3 1.3 11 5.0 0.3 2.1 2 0 0 2 2 2 0 Iodothyronine deiodinase NTP_transf_5 PF14907.1 EIW74412.1 - 0.0069 15.7 0.0 0.0098 15.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised nucleotidyltransferase GST_N_3 PF13417.1 EIW74414.1 - 1.6e-12 47.4 0.0 2.9e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW74414.1 - 2.6e-08 33.7 0.0 4.2e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW74414.1 - 1.1e-07 31.6 0.2 1.8e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW74414.1 - 1.7e-05 24.7 0.0 7.3e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EIW74414.1 - 5e-05 23.1 0.0 9.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GST_N PF02798.15 EIW74414.1 - 8.8e-05 22.6 0.0 0.00024 21.1 0.0 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain DEAD PF00270.24 EIW74415.1 - 2.4e-17 62.9 0.0 1.4e-16 60.4 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW74415.1 - 2.3e-11 43.3 0.1 8.3e-11 41.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW74415.1 - 0.0002 21.2 0.0 0.00056 19.7 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Peptidase_C58 PF03543.9 EIW74415.1 - 0.0066 15.9 0.2 0.013 14.9 0.2 1.5 1 0 0 1 1 1 1 Yersinia/Haemophilus virulence surface antigen WD40 PF00400.27 EIW74417.1 - 1.5e-17 62.6 6.5 0.00061 19.5 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat SRA1 PF07304.6 EIW74417.1 - 1.5e-07 31.3 0.0 3.6e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Steroid receptor RNA activator (SRA1) PAP2 PF01569.16 EIW74419.1 - 8.2e-16 57.8 8.6 8.2e-16 57.8 5.9 2.2 1 1 1 2 2 2 1 PAP2 superfamily Kinocilin PF15033.1 EIW74419.1 - 0.066 12.7 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 Kinocilin protein DUF647 PF04884.9 EIW74420.1 - 3.4e-68 229.5 6.4 2e-67 227.0 4.5 2.0 1 1 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF914 PF06027.7 EIW74421.1 - 1.5e-90 303.4 7.4 2e-90 303.0 5.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 EIW74421.1 - 0.0013 17.7 1.1 0.0025 16.7 0.3 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EIW74421.1 - 0.024 14.6 1.2 0.024 14.6 0.9 3.1 2 1 1 3 3 3 0 EamA-like transporter family zf-CSL PF05207.8 EIW74424.1 - 9.6e-25 85.8 0.7 2.1e-24 84.7 0.5 1.6 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 EIW74424.1 - 0.028 14.3 1.0 0.06 13.3 0.7 1.5 1 0 0 1 1 1 0 Zinc ribbon domain zinc_ribbon_5 PF13719.1 EIW74424.1 - 0.035 13.7 0.3 0.057 13.0 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EIW74424.1 - 0.094 12.4 0.4 0.16 11.6 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain EBV-NA3 PF05009.7 EIW74424.1 - 0.35 10.0 3.1 0.37 9.9 2.1 1.1 1 0 0 1 1 1 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) Nucleoplasmin PF03066.10 EIW74424.1 - 0.59 9.6 6.1 0.6 9.6 4.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EIW74424.1 - 9.1 6.5 12.9 14 5.9 8.9 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4646 PF15496.1 EIW74425.1 - 5.4e-12 45.8 0.0 8.4e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) Ribonuc_red_sm PF00268.16 EIW74428.1 - 8.1e-24 84.0 0.5 1.3e-23 83.3 0.3 1.3 1 1 0 1 1 1 1 Ribonucleotide reductase, small chain SAP PF02037.22 EIW74429.1 - 0.00022 20.6 0.0 0.00054 19.3 0.0 1.6 1 0 0 1 1 1 1 SAP domain HLH PF00010.21 EIW74430.1 - 3.8e-18 64.9 0.3 1.9e-17 62.7 0.0 2.3 2 1 0 2 2 2 1 Helix-loop-helix DNA-binding domain DEAD PF00270.24 EIW74433.1 - 1.5e-15 57.0 0.0 2.5e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EIW74433.1 - 1.5e-06 28.1 0.0 4.4e-06 26.6 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EIW74433.1 - 0.00071 19.2 0.1 0.068 12.9 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain UvrD-helicase PF00580.16 EIW74433.1 - 0.015 14.6 0.0 0.029 13.6 0.0 1.5 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain AAA_11 PF13086.1 EIW74433.1 - 0.068 12.7 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EIW74433.1 - 0.074 12.6 0.0 0.17 11.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EIW74434.1 - 2e-71 240.2 0.0 2.4e-71 240.0 0.0 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 EIW74434.1 - 0.036 13.9 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EIW74434.1 - 0.11 13.2 1.2 0.42 11.4 0.7 2.1 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 EIW74434.1 - 0.21 10.7 0.0 0.32 10.1 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF4131 PF13567.1 EIW74435.1 - 2.7 7.3 6.3 4.3 6.7 1.2 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) UDG PF03167.14 EIW74436.1 - 6.2e-17 61.4 0.0 2.3e-16 59.6 0.0 1.9 1 1 0 1 1 1 1 Uracil DNA glycosylase superfamily Exo70 PF03081.10 EIW74439.1 - 6.6e-31 107.4 0.0 3.3e-30 105.1 0.0 2.0 1 1 0 1 1 1 1 Exo70 exocyst complex subunit Androgen_recep PF02166.11 EIW74439.1 - 0.0044 15.9 1.5 0.09 11.6 0.0 2.5 2 0 0 2 2 2 2 Androgen receptor CBFD_NFYB_HMF PF00808.18 EIW74440.1 - 9.5e-28 96.0 0.4 1.2e-27 95.7 0.3 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EIW74440.1 - 2.2e-06 27.7 0.1 3.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EIW74440.1 - 0.002 17.8 0.0 0.0036 17.0 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit TFIID_20kDa PF03847.8 EIW74440.1 - 0.08 13.2 0.1 0.22 11.8 0.0 1.7 1 1 1 2 2 2 0 Transcription initiation factor TFIID subunit A WD40 PF00400.27 EIW74444.1 - 4e-06 26.4 0.2 0.018 14.8 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat zf-HYPF PF07503.7 EIW74446.1 - 0.24 10.8 1.0 16 5.0 0.1 2.5 2 0 0 2 2 2 0 HypF finger UDG PF03167.14 EIW74447.1 - 1e-12 47.7 0.0 2e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily FAD_binding_3 PF01494.14 EIW74448.1 - 1.3e-67 228.3 0.0 1.8e-67 227.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIW74448.1 - 0.00012 21.9 0.0 0.00032 20.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIW74448.1 - 0.00031 19.9 0.0 0.00056 19.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EIW74448.1 - 0.00033 20.5 0.4 0.0018 18.1 0.3 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW74448.1 - 0.00047 20.2 0.0 0.001 19.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW74448.1 - 0.002 16.6 0.0 0.0034 15.9 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.1 EIW74448.1 - 0.0031 17.3 0.0 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EIW74448.1 - 0.0033 16.3 0.0 0.0076 15.1 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW74448.1 - 0.0033 16.3 0.0 0.0091 14.8 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EIW74448.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DUF1664 PF07889.7 EIW74450.1 - 0.33 10.7 7.3 11 5.8 0.1 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) PAT1 PF09770.4 EIW74450.1 - 0.76 7.9 15.8 0.011 13.9 5.9 1.6 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 MCPsignal PF00015.16 EIW74450.1 - 1.1 8.7 14.1 2 7.8 4.7 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ATG16 PF08614.6 EIW74450.1 - 2.7 7.7 13.7 0.23 11.2 0.3 2.9 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Vps53_N PF04100.7 EIW74450.1 - 4.5 5.9 9.5 8.1 5.1 3.3 2.1 2 0 0 2 2 2 0 Vps53-like, N-terminal TMPIT PF07851.8 EIW74450.1 - 5.6 5.9 9.8 0.68 8.9 3.6 1.7 2 0 0 2 2 2 0 TMPIT-like protein DUF4218 PF13960.1 EIW74451.1 - 0.0015 18.0 0.2 0.0025 17.2 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) MIP PF00230.15 EIW74453.1 - 2.3e-27 95.9 14.6 3.4e-27 95.3 10.1 1.2 1 0 0 1 1 1 1 Major intrinsic protein TSC22 PF01166.13 EIW74455.1 - 0.0034 17.3 0.0 0.0089 15.9 0.0 1.7 1 0 0 1 1 1 1 TSC-22/dip/bun family DUF2711 PF10924.3 EIW74456.1 - 0.02 14.3 0.1 2 7.8 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2711) DUF2702 PF10863.3 EIW74458.1 - 0.071 12.8 0.9 0.16 11.6 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2702) Sec63 PF02889.11 EIW74460.1 - 1.5e-197 655.1 0.0 3.6e-104 348.3 0.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EIW74460.1 - 4.8e-51 172.6 0.0 3.2e-29 101.5 0.0 3.4 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EIW74460.1 - 1.2e-14 54.6 0.0 2e-09 37.5 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EIW74460.1 - 8.4e-13 47.9 0.0 2e-08 33.9 0.0 3.0 2 0 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 EIW74460.1 - 3.2e-07 30.5 0.0 0.0086 16.2 0.0 3.1 2 0 0 2 2 2 2 AAA domain Helicase_C_2 PF13307.1 EIW74460.1 - 0.00012 22.1 0.1 0.53 10.2 0.0 3.6 3 1 0 3 3 3 2 Helicase C-terminal domain PhoH PF02562.11 EIW74460.1 - 0.0032 16.7 0.0 0.22 10.7 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_10 PF12846.2 EIW74460.1 - 0.0083 15.5 0.0 0.64 9.3 0.0 3.8 3 2 1 4 4 4 1 AAA-like domain AAA_23 PF13476.1 EIW74460.1 - 0.26 11.5 1.8 5.9 7.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain Daxx PF03344.10 EIW74460.1 - 9.5 4.5 19.1 20 3.5 13.2 1.4 1 0 0 1 1 1 0 Daxx Family LRR_6 PF13516.1 EIW74462.1 - 0.015 15.3 0.5 64 4.0 0.0 5.6 6 0 0 6 6 6 0 Leucine Rich repeat LRR_8 PF13855.1 EIW74462.1 - 0.052 13.3 10.9 6.8 6.5 0.1 6.0 5 1 0 5 5 5 0 Leucine rich repeat K-box PF01486.12 EIW74462.1 - 0.061 13.1 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 K-box region LRR_4 PF12799.2 EIW74462.1 - 3.1 7.5 11.9 14 5.4 0.1 6.6 6 3 3 9 9 9 0 Leucine Rich repeats (2 copies) Amidohydro_4 PF13147.1 EIW74463.1 - 2.1e-06 28.0 0.1 2.3e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EIW74463.1 - 0.00045 19.9 0.0 0.0005 19.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family FMO-like PF00743.14 EIW74464.1 - 1.3e-23 83.0 0.0 1.2e-19 69.8 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EIW74464.1 - 1.8e-22 80.4 0.0 7.1e-21 75.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW74464.1 - 6.9e-15 55.4 0.0 3.9e-07 30.1 0.0 3.3 2 2 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW74464.1 - 4.9e-10 38.8 0.0 5e-09 35.5 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EIW74464.1 - 5.2e-09 36.3 0.6 0.0024 18.2 0.0 2.8 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW74464.1 - 2.8e-07 30.4 0.0 4e-06 26.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EIW74464.1 - 6.5e-07 28.7 0.1 0.00024 20.2 0.1 2.7 3 0 0 3 3 3 1 FAD binding domain FAD_binding_2 PF00890.19 EIW74464.1 - 1.8e-06 27.0 0.7 0.00015 20.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EIW74464.1 - 2.8e-06 26.5 1.3 0.0058 15.5 0.0 3.5 4 0 0 4 4 4 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIW74464.1 - 3.3e-06 26.2 0.4 0.00053 19.0 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EIW74464.1 - 3.6e-06 26.8 0.5 0.014 15.1 0.0 3.3 3 1 0 3 3 3 2 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 EIW74464.1 - 9.8e-06 24.8 0.0 0.018 14.2 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EIW74464.1 - 4.6e-05 23.1 0.4 0.032 13.8 0.1 2.2 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EIW74464.1 - 6e-05 22.0 2.2 0.034 12.9 0.0 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.9 EIW74464.1 - 8.3e-05 21.2 2.6 0.0001 20.9 0.0 2.2 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_7 PF13241.1 EIW74464.1 - 0.00011 22.3 0.0 0.0069 16.6 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_oxidored PF12831.2 EIW74464.1 - 0.00024 20.3 0.1 0.00049 19.2 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EIW74464.1 - 0.00048 20.2 0.1 0.017 15.2 0.0 2.3 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EIW74464.1 - 0.0013 18.7 0.1 1.2 9.1 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain ApbA PF02558.11 EIW74464.1 - 0.0069 15.8 0.1 0.41 10.0 0.0 2.3 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 EIW74464.1 - 0.0095 15.0 0.0 0.057 12.5 0.0 2.0 2 0 0 2 2 2 1 Thi4 family ELFV_dehydrog PF00208.16 EIW74464.1 - 0.016 14.7 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CPSase_L_chain PF00289.17 EIW74464.1 - 0.039 14.0 0.1 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain AlaDh_PNT_C PF01262.16 EIW74464.1 - 0.062 12.8 0.3 20 4.6 0.0 2.9 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain XdhC_C PF13478.1 EIW74464.1 - 0.063 13.5 0.0 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 XdhC Rossmann domain Mito_fiss_Elm1 PF06258.6 EIW74464.1 - 0.11 11.4 0.0 0.39 9.6 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial fission ELM1 NAD_Gly3P_dh_N PF01210.18 EIW74464.1 - 0.14 11.8 0.2 5.3 6.7 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus RNA_lig_T4_1 PF09511.5 EIW74468.1 - 1e-74 250.7 0.0 3.1e-74 249.1 0.0 1.8 2 0 0 2 2 2 1 RNA ligase tRNA_lig_kinase PF08303.6 EIW74468.1 - 7.2e-24 84.5 0.0 1.3e-23 83.6 0.0 1.4 1 0 0 1 1 1 1 tRNA ligase kinase domain tRNA_lig_CPD PF08302.6 EIW74468.1 - 6.6e-14 51.7 0.0 3.9e-10 39.3 0.0 2.9 2 1 0 2 2 2 2 Fungal tRNA ligase phosphodiesterase domain KTI12 PF08433.5 EIW74468.1 - 0.15 11.2 0.0 0.36 9.9 0.0 1.6 1 0 0 1 1 1 0 Chromatin associated protein KTI12 DUF3392 PF11872.3 EIW74469.1 - 0.0028 17.5 0.8 0.0095 15.8 0.5 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3392) DUF1656 PF07869.7 EIW74469.1 - 0.57 9.9 5.5 11 5.8 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1656) Kinocilin PF15033.1 EIW74470.1 - 0.5 9.8 2.5 0.92 9.0 1.3 1.8 1 1 1 2 2 2 0 Kinocilin protein DUF2838 PF10998.3 EIW74470.1 - 9.7 6.1 10.2 0.22 11.4 1.7 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2838) Ribosomal_L14e PF01929.12 EIW74472.1 - 1.4e-24 86.2 2.5 2.1e-24 85.6 1.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EIW74472.1 - 5.7e-06 25.8 0.8 2.1e-05 24.0 0.4 2.1 2 0 0 2 2 2 1 KOW motif DUF2561 PF10812.3 EIW74473.1 - 0.0063 16.1 0.6 0.01 15.4 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) DAO PF01266.19 EIW74475.1 - 3.8e-25 88.5 0.0 5.3e-25 88.0 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EIW74475.1 - 2.2e-06 26.9 0.1 3.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EIW74475.1 - 4.9e-06 25.6 0.1 2.1e-05 23.5 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EIW74475.1 - 1.2e-05 25.2 0.2 6.3e-05 22.9 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIW74475.1 - 1.5e-05 24.2 0.0 0.00014 21.0 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EIW74475.1 - 2.5e-05 22.9 0.0 4.9e-05 21.9 0.0 1.4 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EIW74475.1 - 6.7e-05 22.8 0.0 0.00048 20.1 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 EIW74475.1 - 0.0011 19.2 0.0 0.0026 17.9 0.0 1.6 2 0 0 2 2 1 1 Putative NAD(P)-binding Pyr_redox PF00070.22 EIW74475.1 - 0.0012 19.2 0.2 0.009 16.4 0.3 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIW74475.1 - 0.0051 15.9 0.1 0.0075 15.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EIW74475.1 - 0.0051 15.7 0.0 0.0072 15.2 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EIW74475.1 - 0.0096 14.8 0.1 0.014 14.3 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EIW74475.1 - 0.011 15.7 0.0 0.019 15.0 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EIW74476.1 - 1.6e-35 123.0 0.1 4.1e-27 95.3 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EIW74476.1 - 0.02 14.9 0.0 0.072 13.1 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAM86 PF14904.1 EIW74477.1 - 0.072 12.8 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function BCDHK_Adom3 PF10436.4 EIW74478.1 - 0.067 12.6 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase Auxin_canalis PF05703.6 EIW74478.1 - 0.073 12.8 2.5 0.041 13.7 0.5 1.6 2 0 0 2 2 2 0 Auxin canalisation DUF3486 PF11985.3 EIW74478.1 - 0.37 10.8 4.3 0.34 10.9 0.8 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3486) AA_permease PF00324.16 EIW74479.1 - 1.3e-110 369.9 38.8 1.6e-110 369.6 26.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIW74479.1 - 1e-32 113.2 40.6 1.3e-32 112.9 28.1 1.1 1 0 0 1 1 1 1 Amino acid permease zf-B_box PF00643.19 EIW74481.1 - 0.59 10.0 8.4 0.089 12.6 2.9 1.8 2 0 0 2 2 2 0 B-box zinc finger DUF1136 PF06582.7 EIW74483.1 - 0.024 14.3 5.4 0.061 13.0 3.7 1.7 1 0 0 1 1 1 0 Repeat of unknown function (DUF1136) Dimer_Tnp_hAT PF05699.9 EIW74484.1 - 4.3e-14 51.9 0.1 1.3e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 EIW74484.1 - 0.00034 20.5 0.8 0.0012 18.7 0.0 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4413) HSP70 PF00012.15 EIW74485.1 - 2e-90 303.4 0.1 2.5e-90 303.1 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIW74485.1 - 7.5e-07 28.0 1.0 7.6e-06 24.7 0.0 2.2 3 0 0 3 3 3 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EIW74485.1 - 0.0044 16.1 1.6 0.0049 16.0 0.0 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase TPP_enzyme_N PF02776.13 EIW74485.1 - 0.079 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain FtsA PF14450.1 EIW74485.1 - 0.16 11.8 2.1 22 4.9 0.0 3.0 3 1 0 3 3 3 0 Cell division protein FtsA Pkinase PF00069.20 EIW74486.1 - 5.5e-10 38.8 0.0 6.2e-10 38.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain GPP34 PF05719.6 EIW74488.1 - 3.8e-63 213.2 0.6 4.7e-63 212.9 0.4 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) 3HCDH_N PF02737.13 EIW74488.1 - 0.13 11.9 0.3 5.8 6.5 0.0 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain G-alpha PF00503.15 EIW74489.1 - 1.5e-109 366.2 0.0 1.7e-109 366.1 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIW74489.1 - 1.6e-11 43.7 0.0 1.5e-06 27.5 0.0 3.3 3 1 0 3 3 3 2 ADP-ribosylation factor family AAA_29 PF13555.1 EIW74489.1 - 0.002 17.6 0.0 0.0053 16.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EIW74489.1 - 0.0079 16.2 0.1 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.1 EIW74489.1 - 0.057 12.9 0.0 7.8 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EIW74489.1 - 0.085 13.0 0.0 0.26 11.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EIW74489.1 - 0.11 11.5 0.0 3.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Ras PF00071.17 EIW74489.1 - 0.12 11.7 0.0 26 4.1 0.0 3.1 3 0 0 3 3 3 0 Ras family DUF4218 PF13960.1 EIW74493.1 - 0.0015 17.9 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) ADH_N PF08240.7 EIW74495.1 - 6.2e-29 99.9 1.5 1.4e-28 98.8 1.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW74495.1 - 1.6e-09 37.3 0.2 4.3e-09 35.9 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EIW74495.1 - 3.2e-07 29.8 0.1 7.5e-07 28.6 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated HI0933_like PF03486.9 EIW74495.1 - 0.0058 15.1 0.2 0.021 13.2 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein ApbA PF02558.11 EIW74495.1 - 0.069 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 EIW74495.1 - 0.12 12.4 0.1 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIW74495.1 - 0.15 11.1 0.1 0.23 10.4 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain AA_permease PF00324.16 EIW74496.1 - 1.2e-109 366.8 42.1 1.4e-109 366.5 29.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIW74496.1 - 6.8e-29 100.6 45.2 8.5e-29 100.3 31.3 1.1 1 0 0 1 1 1 1 Amino acid permease Chs3p PF12271.3 EIW74498.1 - 1.3e-48 165.4 10.8 3e-48 164.2 7.5 1.5 1 1 0 1 1 1 1 Chitin synthase III catalytic subunit DUF2781 PF10914.3 EIW74498.1 - 0.0055 16.4 0.6 0.0055 16.4 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2781) Aldo_ket_red PF00248.16 EIW74499.1 - 2.5e-65 220.1 0.0 3.4e-65 219.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.16 EIW74499.1 - 0.06 13.2 0.1 16 5.5 0.0 3.3 4 0 0 4 4 4 0 Ribbon-helix-helix protein, copG family Aldo_ket_red PF00248.16 EIW74500.1 - 3.1e-65 219.7 0.0 3.6e-65 219.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.16 EIW74500.1 - 0.076 12.9 0.0 5.4 7.0 0.0 3.5 4 0 0 4 4 4 0 Ribbon-helix-helix protein, copG family EHN PF06441.7 EIW74502.1 - 2.9e-30 104.4 0.1 5.5e-30 103.5 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EIW74502.1 - 2.2e-06 27.7 0.8 6.5e-06 26.1 0.2 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW74502.1 - 2.5e-06 27.2 0.0 3.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Atg14 PF10186.4 EIW74503.1 - 8.1e-47 159.6 0.0 9.5e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 DUF4404 PF14357.1 EIW74503.1 - 0.29 11.5 1.7 0.64 10.4 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) Kelch_4 PF13418.1 EIW74504.1 - 5.6e-30 102.8 8.4 1.3e-06 28.0 0.1 7.2 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.1 EIW74504.1 - 2.5e-28 97.5 11.9 1.8e-08 34.2 0.1 7.3 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EIW74504.1 - 1.6e-21 75.4 9.9 4.4e-06 26.6 0.3 5.7 5 1 1 6 6 6 3 Kelch motif DUF4110 PF13422.1 EIW74504.1 - 3.5e-21 74.8 0.2 3.5e-21 74.8 0.1 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4110) Kelch_1 PF01344.20 EIW74504.1 - 5.5e-20 70.6 7.7 1.2e-06 28.0 0.2 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.1 EIW74504.1 - 7.6e-15 54.4 17.2 0.00011 22.1 0.1 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 EIW74504.1 - 4.6e-12 45.1 6.5 0.0022 17.6 0.1 5.3 5 0 0 5 5 5 3 Kelch motif DUF2508 PF10704.4 EIW74504.1 - 1.1 9.4 7.0 0.053 13.6 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2508) COX16 PF14138.1 EIW74504.1 - 4.2 7.6 7.7 19 5.5 5.3 2.1 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 bact-PGI_C PF10432.4 EIW74505.1 - 0.021 14.5 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal region Cu-oxidase PF00394.17 EIW74506.1 - 5e-42 143.4 0.5 2.4e-41 141.2 0.0 2.2 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIW74506.1 - 4.9e-36 123.0 0.0 2.1e-34 117.7 0.0 2.9 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIW74506.1 - 8.5e-36 122.4 6.2 2.2e-32 111.4 0.4 3.9 3 1 0 3 3 3 2 Multicopper oxidase tRNA-synt_1g PF09334.6 EIW74508.1 - 4.3e-15 55.2 0.0 1.2e-14 53.8 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (M) Peptidase_C48 PF02902.14 EIW74508.1 - 0.027 14.0 0.0 0.075 12.6 0.0 1.8 1 0 0 1 1 1 0 Ulp1 protease family, C-terminal catalytic domain tRNA-synt_1g PF09334.6 EIW74509.1 - 2.5e-16 59.3 0.0 3.1e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EIW74509.1 - 1.1e-08 33.6 0.0 1.4e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EIW74509.1 - 2.9e-05 23.3 0.0 4.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EIW74509.1 - 0.0011 17.7 0.0 0.0014 17.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (K) TPR_11 PF13414.1 EIW74510.1 - 6.7e-11 41.6 1.9 9.1e-09 34.8 0.0 3.3 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.23 EIW74510.1 - 6.9e-06 25.4 0.0 1.7 8.4 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat UBA PF00627.26 EIW74510.1 - 5.3e-05 22.9 0.0 0.00015 21.4 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain TPR_2 PF07719.12 EIW74510.1 - 0.001 18.8 4.0 3.1 7.9 0.3 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat DnaJ PF00226.26 EIW74510.1 - 0.0052 16.4 0.0 0.013 15.2 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain DUF4434 PF14488.1 EIW74510.1 - 5.7 6.6 6.4 0.22 11.2 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4434) DUF4199 PF13858.1 EIW74511.1 - 0.0023 17.8 0.6 0.0038 17.1 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) TMEM173 PF15009.1 EIW74511.1 - 0.076 11.7 4.7 0.024 13.4 0.7 1.7 1 1 1 2 2 2 0 Transmembrane protein 173 Herpes_IE2_3 PF03361.9 EIW74511.1 - 0.1 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Herpes virus intermediate/early protein 2/3 Sod_Fe_C PF02777.13 EIW74512.1 - 8.9e-35 118.7 0.0 1.4e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EIW74512.1 - 1.8e-32 111.4 2.4 1.8e-32 111.4 1.6 1.9 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ATP-synt_DE PF00401.15 EIW74512.1 - 0.12 12.2 4.0 0.19 11.6 1.5 2.0 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Carn_acyltransf PF00755.15 EIW74513.1 - 1.2e-169 565.1 0.0 1.5e-169 564.9 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Fe-S_biosyn PF01521.15 EIW74514.1 - 5.2e-08 32.8 0.0 7.2e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis G-patch_2 PF12656.2 EIW74515.1 - 2.8e-26 91.1 0.5 4.9e-25 87.1 0.0 3.3 2 1 1 3 3 3 1 DExH-box splicing factor binding site G-patch PF01585.18 EIW74515.1 - 0.0068 16.1 0.1 0.019 14.7 0.0 1.9 1 0 0 1 1 1 1 G-patch domain Peptidase_S10 PF00450.17 EIW74516.1 - 1.3e-111 373.7 0.0 1.5e-111 373.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EIW74516.1 - 4.6e-06 26.6 0.0 6e-05 23.0 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Aminotran_1_2 PF00155.16 EIW74517.1 - 3.7e-51 174.2 0.0 7.9e-49 166.5 0.0 2.1 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIW74517.1 - 0.00024 20.3 0.0 0.00034 19.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 EIW74517.1 - 0.0018 16.8 0.0 0.005 15.4 0.0 1.6 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.14 EIW74517.1 - 0.0073 15.0 0.0 0.011 14.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V rRNA_processing PF08524.6 EIW74518.1 - 0.057 13.2 17.0 0.099 12.4 11.8 1.3 1 0 0 1 1 1 0 rRNA processing Transformer PF06495.6 EIW74518.1 - 0.63 9.8 9.3 1.2 8.9 6.5 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein IncA PF04156.9 EIW74518.1 - 3.9 7.0 8.6 6.5 6.2 6.0 1.4 1 0 0 1 1 1 0 IncA protein ERGIC_N PF13850.1 EIW74523.1 - 0.06 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Lactamase_B_2 PF12706.2 EIW74524.1 - 1.2e-06 28.1 0.0 3e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.9 EIW74524.1 - 4.1e-05 23.5 0.0 0.00016 21.6 0.0 2.0 1 1 0 1 1 1 1 DNA repair metallo-beta-lactamase Peptidase_S10 PF00450.17 EIW74525.1 - 3e-108 362.6 0.0 3.8e-108 362.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EIW74525.1 - 0.00011 22.1 0.1 0.00091 19.1 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family F-box-like PF12937.2 EIW74526.1 - 7e-10 38.4 0.3 3.3e-09 36.3 0.2 2.3 1 0 0 1 1 1 1 F-box-like Xpo1 PF08389.7 EIW74526.1 - 0.02 14.7 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Exportin 1-like protein RPE65 PF03055.10 EIW74527.1 - 2e-109 366.3 0.0 2.4e-109 366.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Peptidase_M22 PF00814.20 EIW74528.1 - 1.9e-71 240.7 0.0 2.3e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family BcrAD_BadFG PF01869.15 EIW74528.1 - 0.021 14.1 0.0 0.37 10.0 0.0 2.1 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family MFS_1 PF07690.11 EIW74529.1 - 7.4e-23 80.8 19.6 9.5e-23 80.4 13.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Pyr_redox_3 PF13738.1 EIW74531.1 - 2.8e-16 60.1 0.0 2.9e-15 56.8 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW74531.1 - 2.4e-11 43.4 0.0 5.3e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EIW74531.1 - 4.1e-06 26.6 0.0 4.4e-05 23.3 0.0 2.6 3 0 0 3 3 3 1 FAD-NAD(P)-binding FMO-like PF00743.14 EIW74531.1 - 7e-06 24.5 0.0 0.00096 17.4 0.0 3.1 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like DAO PF01266.19 EIW74531.1 - 0.00031 19.7 0.0 0.18 10.7 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIW74531.1 - 0.00032 20.6 0.0 0.022 14.6 0.0 2.9 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW74531.1 - 0.0024 16.8 0.0 0.23 10.3 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 EIW74531.1 - 0.046 12.5 0.0 8.2 5.1 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 EIW74531.1 - 0.19 10.7 0.1 0.58 9.2 0.0 1.7 1 0 0 1 1 1 0 Thi4 family GST_N_3 PF13417.1 EIW74532.1 - 7.8e-11 42.0 0.1 2.2e-10 40.6 0.0 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW74532.1 - 3.2e-08 33.4 0.0 5.4e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIW74532.1 - 0.015 15.7 0.1 0.031 14.7 0.1 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIW74532.1 - 0.03 14.2 0.1 0.07 13.0 0.0 1.6 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Oxidored_nitro PF00148.14 EIW74532.1 - 0.14 10.7 0.0 0.16 10.5 0.0 1.2 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase Peptidase_S10 PF00450.17 EIW74533.1 - 1.9e-116 389.6 0.0 2.3e-116 389.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EIW74533.1 - 2.3e-06 27.6 0.0 6.6e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF423 PF04241.10 EIW74534.1 - 5 7.1 7.7 0.42 10.5 0.6 2.7 2 2 1 3 3 3 0 Protein of unknown function (DUF423) MIP-T3 PF10243.4 EIW74538.1 - 5.9 5.2 48.2 7.8 4.8 33.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 FUSC PF04632.7 EIW74539.1 - 1 7.6 9.5 1.5 7.1 6.6 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family LRR19-TM PF15176.1 EIW74541.1 - 0.0058 16.3 0.0 0.0096 15.5 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat family 19 TM domain WD40 PF00400.27 EIW74542.1 - 8.7e-122 393.1 35.8 4.9e-12 45.2 0.0 13.1 13 0 0 13 13 13 13 WD domain, G-beta repeat eIF2A PF08662.6 EIW74542.1 - 3.5e-14 52.9 0.1 2.4e-06 27.4 0.0 4.2 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIW74542.1 - 5.7e-08 31.3 12.9 0.94 7.5 0.2 8.5 3 2 4 7 7 7 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EIW74542.1 - 9.7e-08 31.7 5.4 0.0037 16.7 0.0 4.2 2 1 1 3 3 3 3 PQQ-like domain Nucleoporin_N PF08801.6 EIW74542.1 - 1.3e-07 30.7 7.8 0.63 8.7 0.0 6.1 1 1 5 6 6 6 4 Nup133 N terminal like PD40 PF07676.7 EIW74542.1 - 3.5e-06 26.5 3.8 4.5 7.0 0.0 6.8 8 0 0 8 8 8 1 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EIW74542.1 - 0.00053 17.9 0.1 3.4 5.3 0.0 4.0 3 1 0 4 4 4 2 IKI3 family PQQ_3 PF13570.1 EIW74542.1 - 0.00087 19.4 3.8 9 6.7 0.1 6.0 6 1 0 6 6 6 1 PQQ-like domain BBS2_Mid PF14783.1 EIW74542.1 - 0.0039 16.9 0.0 5.6 6.7 0.0 4.8 6 1 0 6 6 6 1 Ciliary BBSome complex subunit 2, middle region Hira PF07569.6 EIW74542.1 - 0.011 14.9 0.0 10 5.2 0.0 4.4 5 0 0 5 5 5 0 TUP1-like enhancer of split GST_N_3 PF13417.1 EIW74544.1 - 4.7e-13 49.1 0.1 1.2e-12 47.8 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW74544.1 - 4.3e-10 39.4 0.1 8.1e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW74544.1 - 5.3e-07 29.4 0.0 9.8e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW74544.1 - 3.6e-06 26.8 0.0 5.8e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW74544.1 - 0.0056 17.1 0.0 0.013 15.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW74544.1 - 0.069 13.3 0.0 0.18 11.9 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Trehalase PF01204.13 EIW74545.1 - 1.9e-114 383.1 3.2 1e-104 351.0 0.0 2.0 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.9 EIW74545.1 - 4.8e-05 22.2 0.0 0.00011 21.1 0.0 1.4 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Glyco_hydro_63 PF03200.11 EIW74545.1 - 0.13 10.1 0.1 0.24 9.2 0.0 1.3 1 0 0 1 1 1 0 Mannosyl oligosaccharide glucosidase Kinesin PF00225.18 EIW74546.1 - 7.3e-83 278.0 0.0 3.5e-82 275.8 0.0 1.8 1 1 0 1 1 1 1 Kinesin motor domain Ribosomal_60s PF00428.14 EIW74546.1 - 0.42 11.0 8.2 2.2 8.7 4.4 2.8 2 0 0 2 2 2 0 60s Acidic ribosomal protein tRNA-synt_1g PF09334.6 EIW74547.1 - 2.3e-102 342.5 0.0 3.6e-102 341.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EIW74547.1 - 3.4e-19 68.3 0.4 1.6e-09 36.3 0.0 4.0 2 1 2 4 4 4 4 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EIW74547.1 - 5.3e-10 38.8 0.0 0.00015 20.9 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EIW74547.1 - 0.00011 21.0 0.0 0.0025 16.5 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (K) DUF2889 PF11136.3 EIW74547.1 - 0.041 14.0 0.0 1.6 8.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2889) TniQ PF06527.6 EIW74547.1 - 1.3 9.2 3.5 20 5.3 0.5 3.3 3 1 0 3 3 3 0 TniQ DUF1049 PF06305.6 EIW74548.1 - 0.94 9.0 4.5 3.3 7.2 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) RPN7 PF10602.4 EIW74550.1 - 1e-43 148.7 0.0 2e-43 147.8 0.0 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EIW74550.1 - 1.8e-16 60.3 0.6 1.3e-15 57.6 0.0 2.6 3 1 1 4 4 4 1 PCI domain PCI_Csn8 PF10075.4 EIW74550.1 - 0.0036 17.0 0.4 0.0076 16.0 0.1 1.6 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 TPR_7 PF13176.1 EIW74550.1 - 0.012 15.3 0.1 2.5 8.1 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIW74550.1 - 0.074 12.7 0.1 4.9 6.8 0.0 2.7 1 1 1 2 2 2 0 TPR repeat TPR_12 PF13424.1 EIW74550.1 - 0.26 11.2 5.8 1.7 8.6 0.2 3.7 3 2 0 3 3 3 0 Tetratricopeptide repeat Trehalase PF01204.13 EIW74551.1 - 3e-113 379.1 0.1 7e-102 341.6 0.0 2.1 2 0 0 2 2 2 2 Trehalase GDE_C PF06202.9 EIW74551.1 - 0.00019 20.2 0.1 0.0011 17.7 0.0 1.9 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase Glyco_hydro_31 PF01055.21 EIW74552.1 - 1.6e-160 534.7 5.6 2e-160 534.4 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EIW74552.1 - 3.3e-05 23.6 0.1 0.00013 21.7 0.0 2.0 1 0 0 1 1 1 1 Galactose mutarotase-like p450 PF00067.17 EIW74553.1 - 6.4e-69 232.6 0.0 5.1e-58 196.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 4HBT_3 PF13622.1 EIW74553.1 - 0.037 13.7 1.1 0.087 12.5 0.1 1.9 2 0 0 2 2 2 0 Thioesterase-like superfamily Aminotran_1_2 PF00155.16 EIW74554.1 - 1.7e-36 125.9 0.0 2.3e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EIW74554.1 - 3.9e-06 26.1 0.0 6.6e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EIW74554.1 - 2.2e-05 22.9 0.0 3.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EIW74554.1 - 0.00041 19.5 0.0 0.00074 18.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EIW74554.1 - 0.013 14.2 0.0 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Abhydrolase_6 PF12697.2 EIW74555.1 - 1.5e-13 51.2 1.1 2.6e-13 50.4 0.7 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW74555.1 - 0.0044 16.6 0.0 0.0076 15.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW74555.1 - 0.024 14.3 0.0 0.068 12.9 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Ndr PF03096.9 EIW74555.1 - 0.1 11.0 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 Ndr family Glyco_hydro_47 PF01532.15 EIW74556.1 - 3.2e-115 385.3 0.7 3.6e-115 385.1 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GPI-anchored PF10342.4 EIW74557.1 - 1e-07 32.2 1.4 2.1e-07 31.2 0.9 1.5 1 1 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EIW74557.1 - 0.0028 17.1 0.4 0.014 14.8 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) GFA PF04828.9 EIW74558.1 - 3e-10 39.9 0.0 3e-10 39.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme FSA_C PF10479.4 EIW74558.1 - 0.034 12.2 0.0 0.041 11.9 0.0 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus GPI-anchored PF10342.4 EIW74559.1 - 9.2e-10 38.8 3.2 1.3e-09 38.4 2.2 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EIW74559.1 - 0.009 15.5 0.8 0.011 15.2 0.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 EIW74560.1 - 1.2e-08 35.3 0.7 1.6e-08 34.8 0.5 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF2201_N PF13203.1 EIW74561.1 - 2.4 7.2 8.2 8 5.5 2.3 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain Lipase_3 PF01764.20 EIW74562.1 - 8.5e-16 57.8 0.0 1.5e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EIW74562.1 - 0.023 14.4 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family LysM PF01476.15 EIW74562.1 - 0.035 13.9 0.0 0.09 12.6 0.0 1.7 1 0 0 1 1 1 0 LysM domain FAD_binding_3 PF01494.14 EIW74563.1 - 1.1e-19 70.7 2.1 2.4e-10 40.0 0.1 2.4 2 1 0 2 2 2 2 FAD binding domain FAD_binding_3 PF01494.14 EIW74564.1 - 6.5e-19 68.1 2.0 4.8e-17 62.0 1.4 2.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIW74564.1 - 0.001 19.0 0.3 0.0031 17.5 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EIW74564.1 - 0.016 14.0 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase DAO PF01266.19 EIW74564.1 - 0.025 13.4 1.8 0.036 12.9 0.6 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW74564.1 - 0.11 12.9 0.1 1.3 9.4 0.1 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW74564.1 - 0.12 11.4 0.0 0.26 10.3 0.0 1.5 2 0 0 2 2 2 0 Thi4 family Aldedh PF00171.17 EIW74565.1 - 2.4e-184 613.0 0.1 2.7e-184 612.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIW74565.1 - 1.6e-07 30.4 0.0 2.5e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) GMC_oxred_N PF00732.14 EIW74566.1 - 2.2e-59 201.0 0.0 2.9e-59 200.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIW74566.1 - 6.7e-32 110.7 0.2 1.2e-31 109.9 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIW74566.1 - 6.2e-09 35.2 0.1 0.00055 18.9 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW74566.1 - 9e-06 24.7 1.3 0.0011 17.8 0.1 2.6 3 0 0 3 3 3 2 FAD binding domain NAD_binding_8 PF13450.1 EIW74566.1 - 9.1e-06 25.6 0.5 3.8e-05 23.6 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EIW74566.1 - 0.00016 20.6 0.1 0.031 13.1 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EIW74566.1 - 0.00045 19.2 0.0 0.00071 18.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EIW74566.1 - 0.0012 18.9 0.0 1.1 9.2 0.1 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW74566.1 - 0.0046 15.4 0.1 0.018 13.4 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EIW74566.1 - 0.0091 15.8 0.0 0.024 14.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIW74566.1 - 0.012 14.6 0.0 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 EIW74566.1 - 0.06 13.1 0.2 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 EIW74566.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Ion_trans PF00520.26 EIW74567.1 - 2.3e-16 59.6 15.9 3.6e-16 59.0 11.0 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.11 EIW74567.1 - 6.5e-10 38.5 8.5 6.5e-10 38.5 5.9 2.6 2 2 0 2 2 2 1 Ion channel p450 PF00067.17 EIW74568.1 - 5.9e-69 232.7 0.0 6.9e-69 232.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aldedh PF00171.17 EIW74570.1 - 2.6e-180 599.7 0.3 2.9e-180 599.5 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIW74570.1 - 9.6e-05 21.2 0.0 0.00022 20.0 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) PRP1_N PF06424.7 EIW74572.1 - 3.5e-47 160.0 3.3 3.5e-47 160.0 2.3 2.0 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EIW74572.1 - 1.4e-25 87.3 44.2 0.002 18.5 0.3 14.7 6 4 9 15 15 15 7 Tetratricopeptide repeat TPR_16 PF13432.1 EIW74572.1 - 1.2e-17 64.0 41.1 1.4e-07 31.9 0.2 9.6 9 2 2 11 11 11 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIW74572.1 - 2.3e-17 63.0 17.0 0.0025 18.1 0.0 10.4 8 4 4 12 12 11 5 Tetratricopeptide repeat TPR_11 PF13414.1 EIW74572.1 - 3.7e-07 29.6 6.7 0.00019 20.9 0.1 6.1 7 1 0 7 7 7 1 TPR repeat TPR_2 PF07719.12 EIW74572.1 - 0.00011 21.8 14.8 0.041 13.7 0.4 7.9 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIW74572.1 - 0.00089 19.1 3.8 0.16 11.8 0.0 5.5 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIW74572.1 - 0.0025 18.1 9.0 48 4.7 0.0 7.7 8 0 0 8 8 6 0 Tetratricopeptide repeat NARP1 PF12569.3 EIW74572.1 - 0.0066 15.2 0.0 0.0066 15.2 0.0 4.1 4 1 1 5 5 5 1 NMDA receptor-regulated protein 1 TPR_8 PF13181.1 EIW74572.1 - 0.046 13.5 0.4 2.7 7.9 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat Ferritin PF00210.19 EIW74572.1 - 0.048 13.4 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Ferritin-like domain TPR_9 PF13371.1 EIW74572.1 - 0.057 13.2 15.8 0.093 12.5 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIW74572.1 - 0.1 12.2 0.1 16 5.2 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat NAD_binding_10 PF13460.1 EIW74573.1 - 2.7e-15 56.8 0.2 3.5e-15 56.4 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW74573.1 - 1.3e-07 31.3 0.1 4.5e-07 29.5 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIW74573.1 - 6.9e-07 28.7 0.4 3.1e-06 26.6 0.5 1.7 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 EIW74573.1 - 3.8e-05 22.5 0.0 0.049 12.3 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_2 PF03446.10 EIW74573.1 - 3.9e-05 23.5 0.1 6.1e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.20 EIW74573.1 - 0.00033 20.6 0.7 0.00063 19.7 0.5 1.5 1 0 0 1 1 1 1 short chain dehydrogenase UDPG_MGDP_dh_N PF03721.9 EIW74573.1 - 0.00096 18.5 0.1 0.0015 17.9 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain RmlD_sub_bind PF04321.12 EIW74573.1 - 0.0012 17.7 0.1 0.013 14.3 0.1 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.13 EIW74573.1 - 0.0013 18.6 0.1 0.0023 17.8 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain THF_DHG_CYH_C PF02882.14 EIW74573.1 - 0.004 16.2 0.2 0.021 13.9 0.0 2.0 1 1 1 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 EIW74573.1 - 0.0049 16.9 0.3 0.0079 16.3 0.2 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EIW74573.1 - 0.0085 15.7 0.6 0.027 14.1 0.4 1.8 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.4 EIW74573.1 - 0.052 13.2 0.9 0.1 12.3 0.2 1.9 2 0 0 2 2 2 0 Rossmann-like domain DapB_N PF01113.15 EIW74573.1 - 0.06 13.2 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.21 EIW74573.1 - 0.095 12.2 0.3 1.8 8.1 0.1 2.3 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Ribonuclease_3 PF00636.21 EIW74574.1 - 2.2e-42 144.1 0.0 7.1e-23 81.2 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EIW74574.1 - 1.2e-30 106.1 1.0 4.8e-13 49.1 0.0 4.2 3 1 0 3 3 3 3 Ribonuclease-III-like DEAD PF00270.24 EIW74574.1 - 6.1e-17 61.6 0.0 1.2e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW74574.1 - 1.8e-13 50.1 0.0 4.8e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 EIW74574.1 - 3.5e-13 49.1 0.1 1.4e-12 47.1 0.0 2.1 2 0 0 2 2 2 1 Dicer dimerisation domain ResIII PF04851.10 EIW74574.1 - 3.9e-09 36.5 0.0 1.2e-08 35.0 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit dsrm PF00035.20 EIW74574.1 - 0.022 15.3 0.0 0.1 13.1 0.1 2.1 2 0 0 2 2 2 0 Double-stranded RNA binding motif GTP_CH_N PF12471.3 EIW74575.1 - 8.3e-90 299.6 0.0 1.3e-89 298.9 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EIW74575.1 - 8.7e-15 54.3 0.0 1.5e-14 53.6 0.0 1.3 1 0 0 1 1 1 1 GTP cyclohydrolase II UbiA PF01040.13 EIW74576.1 - 2.3e-16 59.8 8.9 3.1e-16 59.3 6.2 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family UbiA PF01040.13 EIW74578.1 - 5.6e-16 58.5 12.8 8.6e-16 57.9 8.9 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF423 PF04241.10 EIW74578.1 - 0.027 14.4 1.1 0.12 12.3 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF423) DUF3959 PF13105.1 EIW74578.1 - 0.18 11.1 1.9 0.21 10.8 0.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3959) Bax1-I PF01027.15 EIW74578.1 - 0.67 9.5 12.6 12 5.4 5.6 2.9 2 1 0 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 MFS_1 PF07690.11 EIW74580.1 - 1.4e-24 86.4 54.1 1.9e-19 69.5 18.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EIW74580.1 - 0.093 12.5 8.1 4.1 7.2 0.6 3.9 3 1 2 5 5 5 0 MFS_1 like family UPF0233 PF06781.7 EIW74580.1 - 0.18 11.4 0.8 4 7.1 0.0 3.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) TIM21 PF08294.6 EIW74580.1 - 2.8 7.5 5.1 6.4 6.4 0.8 2.6 2 1 0 3 3 3 0 TIM21 Oxidored_FMN PF00724.15 EIW74581.1 - 3.6e-95 318.8 0.0 4.1e-95 318.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ketoacyl-synt PF00109.21 EIW74583.1 - 6.5e-74 248.6 0.1 1.2e-73 247.7 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain GMC_oxred_N PF00732.14 EIW74583.1 - 8.9e-56 189.1 0.0 1.6e-55 188.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Acyl_transf_1 PF00698.16 EIW74583.1 - 4e-48 164.3 0.0 6.3e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EIW74583.1 - 3.5e-34 117.1 3.0 2.4e-33 114.4 2.8 1.9 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain GMC_oxred_C PF05199.8 EIW74583.1 - 6e-32 110.9 0.1 1.1e-31 110.0 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase PS-DH PF14765.1 EIW74583.1 - 2.7e-21 76.0 2.1 5.1e-21 75.1 1.5 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.15 EIW74583.1 - 1.1e-18 68.3 0.0 4.9e-18 66.2 0.0 2.2 2 1 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 EIW74583.1 - 7.6e-13 48.5 0.4 1.9e-12 47.2 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EIW74583.1 - 1.2e-11 44.9 4.2 1.3e-09 38.3 0.3 3.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW74583.1 - 3.7e-08 33.2 0.2 1.3e-05 24.9 0.0 3.6 3 0 0 3 3 3 1 Alpha/beta hydrolase family Thiolase_N PF00108.18 EIW74583.1 - 7.4e-06 25.1 0.1 1.8e-05 23.8 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain PGAP1 PF07819.8 EIW74583.1 - 0.00029 20.4 0.0 0.00063 19.3 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein NAD_binding_8 PF13450.1 EIW74583.1 - 0.00045 20.1 0.0 0.0017 18.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF2974 PF11187.3 EIW74583.1 - 0.0019 17.5 0.0 0.004 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) GST_N_3 PF13417.1 EIW74584.1 - 1.7e-10 40.9 0.0 3.8e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW74584.1 - 1.6e-07 31.2 0.0 2.8e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW74584.1 - 1.8e-07 31.0 0.0 3.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW74584.1 - 2.8e-06 27.1 0.0 4.6e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW74584.1 - 0.00046 20.6 0.1 0.00079 19.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIW74586.1 - 9.6e-14 51.3 0.1 2.9e-13 49.8 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW74586.1 - 9.6e-11 41.5 0.0 1.9e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW74586.1 - 1.8e-07 31.2 0.0 3.6e-06 27.0 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW74586.1 - 6.3e-05 22.8 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIW74586.1 - 0.0085 15.9 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ATP11 PF06644.6 EIW74587.1 - 0.24 10.8 3.7 0.3 10.5 2.5 1.1 1 0 0 1 1 1 0 ATP11 protein Hydrophobin PF01185.13 EIW74588.1 - 4.5e-17 62.2 8.0 5.6e-17 61.9 5.6 1.1 1 0 0 1 1 1 1 Fungal hydrophobin MFS_1 PF07690.11 EIW74589.1 - 4.4e-35 121.0 26.4 4.4e-35 121.0 18.3 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW74589.1 - 1.4e-33 116.1 25.8 1.1e-32 113.2 17.9 2.3 1 1 1 2 2 2 1 Sugar (and other) transporter LacY_symp PF01306.14 EIW74589.1 - 0.00011 20.9 8.2 0.00025 19.7 5.7 1.5 1 1 0 1 1 1 1 LacY proton/sugar symporter BTB PF00651.26 EIW74591.1 - 6.4e-05 22.8 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain GNAT_acetyltr_2 PF13718.1 EIW74592.1 - 5.6e-76 254.2 0.0 1.1e-75 253.2 0.0 1.5 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EIW74592.1 - 1.2e-66 223.7 0.1 3.5e-66 222.1 0.0 1.9 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 EIW74592.1 - 9.6e-39 130.9 0.3 2.3e-38 129.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EIW74592.1 - 1.8e-31 108.2 0.1 5.1e-31 106.7 0.1 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 EIW74592.1 - 2.4e-06 27.6 0.0 5.8e-05 23.1 0.0 2.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW74592.1 - 0.083 12.9 0.0 0.33 11.0 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family Aldo_ket_red PF00248.16 EIW74594.1 - 5.4e-62 209.1 0.1 6.2e-62 208.9 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ecl1 PF12855.2 EIW74595.1 - 7.6e-09 34.7 8.6 0.00035 19.8 0.8 2.4 2 0 0 2 2 2 2 Life-span regulatory factor zf-TRM13_CCCH PF11722.3 EIW74595.1 - 0.00087 18.6 0.4 1.3 8.5 0.0 2.7 2 0 0 2 2 2 2 CCCH zinc finger in TRM13 protein TetM_leader PF08076.6 EIW74595.1 - 0.022 14.2 1.0 0.15 11.5 0.4 2.1 2 0 0 2 2 2 0 Tetracycline resistance determinant leader peptide DUF2256 PF10013.4 EIW74595.1 - 0.29 10.9 3.5 6.5 6.5 0.2 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-MYND PF01753.13 EIW74595.1 - 0.33 10.8 11.4 1.1 9.2 1.5 2.5 2 0 0 2 2 2 0 MYND finger Metallothio_Pro PF02069.11 EIW74595.1 - 0.34 10.7 13.0 1.8 8.4 1.7 2.8 2 1 0 2 2 2 0 Prokaryotic metallothionein GcrA PF07750.6 EIW74595.1 - 3.3 7.8 5.3 19 5.4 0.2 2.3 2 0 0 2 2 2 0 GcrA cell cycle regulator IIGP PF05049.8 EIW74597.1 - 9.2e-26 90.5 0.0 4.5e-25 88.2 0.0 1.8 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.18 EIW74597.1 - 1.7e-06 28.0 0.0 3.6e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EIW74597.1 - 0.00012 22.4 0.4 0.0003 21.1 0.1 2.0 2 1 0 2 2 2 1 ABC transporter DUF258 PF03193.11 EIW74597.1 - 0.0014 17.8 0.0 0.0023 17.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EIW74597.1 - 0.0054 16.2 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EIW74597.1 - 0.0078 16.3 0.0 0.022 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW74597.1 - 0.0087 16.0 0.1 0.03 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 EIW74597.1 - 0.019 15.4 0.0 0.044 14.2 0.0 1.7 1 1 0 1 1 1 0 Miro-like protein DSX_dimer PF08828.5 EIW74597.1 - 0.026 14.0 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 Doublesex dimerisation domain Dynamin_N PF00350.18 EIW74597.1 - 0.029 14.1 0.1 0.11 12.3 0.1 1.9 1 1 0 1 1 1 0 Dynamin family AAA_10 PF12846.2 EIW74597.1 - 0.063 12.7 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA-like domain AAA_21 PF13304.1 EIW74597.1 - 0.092 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain Band_7 PF01145.20 EIW74597.1 - 0.097 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 SPFH domain / Band 7 family AAA_17 PF13207.1 EIW74597.1 - 0.15 12.9 0.3 0.38 11.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.12 EIW74597.1 - 0.26 11.0 1.3 0.46 10.2 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 HAD_2 PF13419.1 EIW74598.1 - 1.5e-13 51.3 0.1 1.2e-08 35.3 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIW74598.1 - 4e-13 50.2 0.0 7.7e-12 46.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIW74598.1 - 8.8e-09 34.9 0.0 1.7e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EIW74598.1 - 0.0023 18.0 0.0 0.0039 17.3 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrophobin PF01185.13 EIW74599.1 - 4.4e-19 68.6 9.5 6.2e-19 68.2 6.6 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Fungal_trans PF04082.13 EIW74600.1 - 2.5e-10 39.6 0.7 3.7e-10 39.0 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW74600.1 - 0.012 15.5 0.5 0.02 14.8 0.4 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain UvrB PF12344.3 EIW74600.1 - 0.08 12.4 0.0 0.2 11.1 0.0 1.6 1 0 0 1 1 1 0 Ultra-violet resistance protein B HECT PF00632.20 EIW74601.1 - 1.4e-94 316.8 0.0 1.9e-94 316.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 EIW74601.1 - 0.00042 19.7 0.1 0.0013 18.2 0.1 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Zn_clus PF00172.13 EIW74602.1 - 7.8e-10 38.5 7.3 1.3e-09 37.8 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EIW74602.1 - 6.9e-08 31.6 0.1 1.1e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EIW74604.1 - 3.7e-05 23.7 17.1 0.033 14.5 0.5 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EIW74604.1 - 0.00013 22.1 16.5 0.0088 16.3 0.4 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type Evr1_Alr PF04777.8 EIW74604.1 - 0.2 11.5 3.5 0.22 11.4 1.3 1.8 1 1 0 1 1 1 0 Erv1 / Alr family ICMT PF04140.9 EIW74605.1 - 9.2e-14 51.4 0.5 6.9e-13 48.6 0.1 2.2 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIW74605.1 - 2.2e-11 43.8 0.6 1.9e-10 40.8 0.2 2.3 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EIW74605.1 - 0.012 14.1 0.3 0.02 13.4 0.2 1.2 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family IIGP PF05049.8 EIW74606.1 - 8e-45 153.2 0.1 1.1e-21 77.1 0.0 3.3 2 2 0 2 2 2 2 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.18 EIW74606.1 - 1.3e-13 50.9 0.0 1.7e-05 24.7 0.0 3.2 3 1 0 3 3 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EIW74606.1 - 1.5e-06 27.6 3.0 0.045 13.2 0.0 3.9 4 0 0 4 4 4 2 P-loop containing region of AAA domain ABC_tran PF00005.22 EIW74606.1 - 8e-06 26.1 1.5 0.053 13.8 0.0 3.2 2 2 0 2 2 2 2 ABC transporter AAA_22 PF13401.1 EIW74606.1 - 1e-05 25.6 0.0 0.068 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EIW74606.1 - 2.6e-05 24.6 0.0 0.19 12.2 0.0 2.8 2 1 0 2 2 2 2 Miro-like protein AAA_16 PF13191.1 EIW74606.1 - 5.4e-05 23.2 1.8 0.044 13.7 0.0 3.2 4 0 0 4 4 4 1 AAA ATPase domain DUF258 PF03193.11 EIW74606.1 - 0.00018 20.7 0.0 0.24 10.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Viral_helicase1 PF01443.13 EIW74606.1 - 0.00026 20.6 0.1 1.8 8.0 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 EIW74606.1 - 0.00092 19.5 0.3 1.3 9.3 0.0 3.6 4 0 0 4 4 3 1 AAA domain Dynamin_N PF00350.18 EIW74606.1 - 0.00096 19.0 0.0 0.8 9.5 0.0 2.7 2 1 0 2 2 2 2 Dynamin family AAA_21 PF13304.1 EIW74606.1 - 0.0011 18.9 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EIW74606.1 - 0.0015 18.0 0.8 0.4 10.0 0.0 2.7 2 1 0 3 3 3 1 AAA-like domain Ribosomal_S8 PF00410.14 EIW74606.1 - 0.0031 17.3 0.0 3 7.6 0.0 2.3 2 0 0 2 2 2 2 Ribosomal protein S8 FeoB_N PF02421.13 EIW74606.1 - 0.0033 16.7 0.0 1.6 8.0 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_30 PF13604.1 EIW74606.1 - 0.0041 16.7 4.9 0.18 11.3 0.1 2.9 3 0 0 3 3 3 1 AAA domain ATP_bind_1 PF03029.12 EIW74606.1 - 0.0044 16.6 0.2 1.2 8.6 0.0 2.8 3 0 0 3 3 3 1 Conserved hypothetical ATP binding protein SMC_N PF02463.14 EIW74606.1 - 0.0079 15.4 0.5 0.94 8.6 0.0 2.4 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain PTS_IIA PF02255.11 EIW74606.1 - 0.011 15.5 0.3 3.2 7.7 0.0 2.5 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit AAA_28 PF13521.1 EIW74606.1 - 0.013 15.4 0.0 2.9 7.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EIW74606.1 - 0.014 15.7 0.6 6.4 7.0 0.1 2.6 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.9 EIW74606.1 - 0.014 14.3 0.1 0.6 9.0 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase cobW PF02492.14 EIW74606.1 - 0.04 13.3 0.4 3.2 7.1 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Docking PF08990.6 EIW74606.1 - 0.048 12.8 4.2 3.8 6.8 0.1 3.4 3 0 0 3 3 3 0 Erythronolide synthase docking ArgK PF03308.11 EIW74606.1 - 0.055 12.2 0.1 3.6 6.2 0.0 2.5 2 0 0 2 2 2 0 ArgK protein AAA_17 PF13207.1 EIW74606.1 - 0.061 14.1 8.6 0.27 12.0 0.7 3.6 2 2 0 2 2 2 0 AAA domain Strep_pep PF14404.1 EIW74606.1 - 0.064 13.4 0.6 7.1 6.9 0.0 2.6 2 0 0 2 2 2 0 Ribosomally synthesized peptide in Streptomyces species AAA_33 PF13671.1 EIW74606.1 - 0.29 10.9 2.7 14 5.5 0.1 3.1 2 2 0 2 2 2 0 AAA domain DUF87 PF01935.12 EIW74606.1 - 0.65 9.7 8.3 0.31 10.8 0.4 2.7 3 0 0 3 3 2 0 Domain of unknown function DUF87 IIGP PF05049.8 EIW74607.1 - 1.5e-23 83.2 0.1 8e-23 80.8 0.0 2.0 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.18 EIW74607.1 - 8.8e-07 28.8 0.0 2e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIW74607.1 - 0.0085 16.5 0.1 0.027 14.9 0.0 2.0 2 1 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 EIW74607.1 - 0.0096 15.4 0.1 0.043 13.3 0.0 2.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EIW74607.1 - 0.011 15.8 0.2 0.075 13.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EIW74607.1 - 0.12 11.8 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EIW74607.1 - 0.14 12.0 0.1 0.14 12.0 0.1 3.1 2 1 1 3 3 2 0 AAA ATPase domain ABC_tran PF00005.22 EIW74607.1 - 0.36 11.1 9.4 0.14 12.4 0.8 2.9 2 1 0 2 2 2 0 ABC transporter Borrelia_P83 PF05262.6 EIW74607.1 - 1.9 6.6 20.1 0.094 10.9 10.5 1.4 2 0 0 2 2 2 0 Borrelia P83/100 protein AAA_23 PF13476.1 EIW74607.1 - 3.8 7.7 10.1 2.6 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EIW74607.1 - 8.4 7.2 6.8 2.7 8.8 1.4 2.8 2 1 0 2 2 2 0 AAA domain DPBB_1 PF03330.13 EIW74608.1 - 3.5e-08 33.3 0.2 3e-07 30.3 0.1 2.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIW74608.1 - 0.035 13.7 0.0 0.062 12.9 0.0 1.3 1 1 0 1 1 1 0 Barwin family GDA1_CD39 PF01150.12 EIW74609.1 - 4.4e-85 285.7 0.0 6e-85 285.3 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Abi PF02517.11 EIW74610.1 - 0.0049 16.9 1.3 0.0049 16.9 0.9 2.7 2 1 0 2 2 2 1 CAAX protease self-immunity EXS PF03124.9 EIW74610.1 - 0.089 11.7 6.4 2.4 7.1 0.1 2.4 2 0 0 2 2 2 0 EXS family UreF PF01730.11 EIW74610.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 UreF Aldo_ket_red PF00248.16 EIW74611.1 - 9.3e-72 241.2 0.0 1.1e-71 240.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.16 EIW74611.1 - 0.052 13.4 0.4 0.34 10.8 0.0 2.5 3 0 0 3 3 3 0 Ribbon-helix-helix protein, copG family Phageshock_PspD PF09584.5 EIW74611.1 - 0.071 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Phage shock protein PspD (Phageshock_PspD) Ifi-6-16 PF06140.8 EIW74612.1 - 0.0098 15.6 24.6 0.016 14.9 17.1 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family FRQ PF09421.5 EIW74612.1 - 0.091 10.5 2.6 0.1 10.3 1.8 1.2 1 0 0 1 1 1 0 Frequency clock protein Focal_AT PF03623.8 EIW74613.1 - 0.098 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Focal adhesion targeting region IIGP PF05049.8 EIW74614.1 - 1.3e-22 80.2 0.0 7.2e-22 77.7 0.0 1.8 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.18 EIW74614.1 - 4.5e-06 26.5 0.0 1e-05 25.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EIW74614.1 - 0.0028 17.7 0.0 0.0054 16.8 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EIW74614.1 - 0.0032 16.9 0.1 0.03 13.8 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EIW74614.1 - 0.0096 15.9 0.0 0.061 13.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 EIW74614.1 - 0.012 16.1 0.0 0.026 15.0 0.0 1.7 1 1 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 EIW74614.1 - 0.018 15.3 0.2 0.029 14.6 0.2 1.7 1 1 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.13 EIW74614.1 - 0.06 12.8 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EIW74614.1 - 0.083 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIW74614.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 EIW74614.1 - 0.24 12.2 1.2 0.47 11.2 0.8 2.0 1 1 0 1 1 1 0 AAA domain Ifi-6-16 PF06140.8 EIW74615.1 - 0.00017 21.3 13.4 0.00017 21.3 9.3 3.0 3 1 0 3 3 3 1 Interferon-induced 6-16 family DUF3188 PF11384.3 EIW74615.1 - 0.35 10.4 5.3 0.56 9.8 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) IIGP PF05049.8 EIW74616.1 - 3.9e-47 160.8 0.0 8.5e-25 87.3 0.0 2.4 2 1 0 2 2 2 2 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.18 EIW74616.1 - 3.5e-16 59.1 0.0 4.9e-07 29.7 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EIW74616.1 - 2.7e-10 40.7 0.0 1.8e-05 25.2 0.0 3.1 2 1 0 2 2 2 2 Miro-like protein ABC_tran PF00005.22 EIW74616.1 - 1.3e-06 28.7 11.9 0.0022 18.3 0.1 3.8 3 2 0 3 3 3 2 ABC transporter AAA_29 PF13555.1 EIW74616.1 - 2.4e-06 26.9 0.8 0.05 13.1 0.0 3.3 4 0 0 4 4 3 2 P-loop containing region of AAA domain DUF258 PF03193.11 EIW74616.1 - 4.4e-06 25.9 0.0 0.05 12.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EIW74616.1 - 1.4e-05 24.7 0.5 0.065 12.6 0.0 3.0 2 1 1 3 3 3 2 FtsK/SpoIIIE family FeoB_N PF02421.13 EIW74616.1 - 3.5e-05 23.1 0.0 0.081 12.2 0.0 2.5 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA_21 PF13304.1 EIW74616.1 - 6.4e-05 23.0 0.1 0.39 10.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIW74616.1 - 7e-05 22.9 0.0 0.66 10.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain HAD_2 PF13419.1 EIW74616.1 - 0.00046 20.4 5.1 0.49 10.5 0.1 3.3 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase ATP_bind_1 PF03029.12 EIW74616.1 - 0.00079 19.0 1.6 1.3 8.4 0.0 3.3 3 0 0 3 3 3 2 Conserved hypothetical ATP binding protein Viral_helicase1 PF01443.13 EIW74616.1 - 0.001 18.6 0.1 0.42 10.1 0.0 2.8 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase SMC_N PF02463.14 EIW74616.1 - 0.0011 18.2 0.6 1.1 8.3 0.0 2.9 3 0 0 3 3 2 2 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.18 EIW74616.1 - 0.002 17.9 14.0 0.11 12.2 0.0 4.1 3 2 0 3 3 3 2 Dynamin family AAA_10 PF12846.2 EIW74616.1 - 0.0023 17.4 4.2 0.3 10.4 0.0 3.2 3 0 0 3 3 3 2 AAA-like domain cobW PF02492.14 EIW74616.1 - 0.0093 15.4 0.4 4.2 6.7 0.0 2.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EIW74616.1 - 0.011 16.5 10.4 0.48 11.2 0.0 4.0 3 2 0 3 3 3 0 AAA domain DUF87 PF01935.12 EIW74616.1 - 0.013 15.3 16.8 0.075 12.8 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 NACHT PF05729.7 EIW74616.1 - 0.029 14.0 0.5 2.6 7.6 0.0 3.0 3 0 0 3 3 2 0 NACHT domain Herpes_Helicase PF02689.9 EIW74616.1 - 0.029 12.1 1.0 4.5 4.8 0.5 2.5 2 1 0 2 2 2 0 Helicase MobB PF03205.9 EIW74616.1 - 0.053 13.2 0.1 15 5.3 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EIW74616.1 - 0.071 13.0 24.7 0.16 11.9 0.1 5.1 3 2 1 5 5 4 0 AAA ATPase domain PTS_IIA PF02255.11 EIW74616.1 - 0.17 11.7 10.1 19 5.2 0.0 3.7 3 0 0 3 3 3 0 PTS system, Lactose/Cellobiose specific IIA subunit VSG_B PF13206.1 EIW74616.1 - 0.19 10.8 13.9 0.3 10.1 9.7 1.2 1 0 0 1 1 1 0 Trypanosomal VSG domain AAA_18 PF13238.1 EIW74616.1 - 1.1 9.5 9.2 4.7 7.5 0.0 4.0 4 1 0 4 4 2 0 AAA domain AAA PF00004.24 EIW74616.1 - 2.8 8.1 4.7 51 4.0 0.0 4.3 5 0 0 5 5 4 0 ATPase family associated with various cellular activities (AAA) IncA PF04156.9 EIW74616.1 - 4.3 6.8 16.0 7 6.1 11.1 1.3 1 0 0 1 1 1 0 IncA protein SPX PF03105.14 EIW74616.1 - 7.1 6.3 10.9 13 5.4 7.6 1.4 1 0 0 1 1 1 0 SPX domain DPBB_1 PF03330.13 EIW74617.1 - 2.6e-06 27.3 0.0 3.9e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DAHP_synth_2 PF01474.11 EIW74618.1 - 5.6e-180 598.3 0.0 6.4e-180 598.2 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family WD40 PF00400.27 EIW74619.1 - 4.1e-54 178.6 6.0 1e-10 41.0 0.1 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EIW74619.1 - 1.1e-05 23.7 0.2 0.1 10.7 0.0 3.6 2 1 1 4 4 4 2 Nucleoporin Nup120/160 DUF3721 PF12518.3 EIW74619.1 - 0.19 11.3 2.1 0.51 9.9 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function Nucleoporin_N PF08801.6 EIW74619.1 - 0.22 10.2 0.0 3 6.4 0.0 2.1 1 1 1 2 2 2 0 Nup133 N terminal like Mito_carr PF00153.22 EIW74620.1 - 7.1e-27 92.9 4.6 8.5e-15 54.2 0.3 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_S7 PF00177.16 EIW74621.1 - 5.5e-19 68.2 0.1 7.2e-19 67.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e DPBB_1 PF03330.13 EIW74622.1 - 1.2e-05 25.1 0.0 5.2e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIW74622.1 - 0.001 18.7 0.2 0.0016 18.0 0.1 1.5 1 1 0 1 1 1 1 Barwin family Cys_rich_CPXG PF14255.1 EIW74622.1 - 0.042 13.6 1.1 0.089 12.6 0.8 1.5 1 0 0 1 1 1 0 Cysteine-rich CPXCG IIGP PF05049.8 EIW74625.1 - 1.9e-12 46.7 0.0 3e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.18 EIW74625.1 - 0.066 13.1 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase LMWPc PF01451.16 EIW74625.1 - 0.088 13.1 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 Low molecular weight phosphotyrosine protein phosphatase IIGP PF05049.8 EIW74626.1 - 1.9e-21 76.2 0.0 1e-20 73.8 0.0 1.8 1 1 0 1 1 1 1 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.18 EIW74626.1 - 1.7e-07 31.1 0.0 3.4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EIW74626.1 - 0.0027 17.9 0.0 0.0049 17.1 0.0 1.7 1 1 0 1 1 1 1 ABC transporter Miro PF08477.8 EIW74626.1 - 0.0064 16.9 0.0 0.013 15.9 0.0 1.6 1 1 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 EIW74626.1 - 0.0096 15.4 0.1 0.11 12.0 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 EIW74626.1 - 0.017 14.6 0.1 0.87 9.0 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EIW74626.1 - 0.02 15.0 0.0 0.12 12.5 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 EIW74626.1 - 0.027 13.6 0.0 0.043 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EIW74626.1 - 0.046 13.5 0.2 0.1 12.3 0.1 2.0 1 1 0 1 1 1 0 Dynamin family Viral_helicase1 PF01443.13 EIW74626.1 - 0.052 13.0 0.0 0.099 12.1 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EIW74626.1 - 0.078 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 EIW74626.1 - 0.095 12.2 0.2 0.32 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EIW74626.1 - 0.12 11.7 0.1 0.19 11.1 0.1 1.4 1 1 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 EIW74626.1 - 0.12 12.2 0.1 0.57 10.0 0.0 2.2 1 1 0 2 2 2 0 AAA domain AAA_21 PF13304.1 EIW74626.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain IIGP PF05049.8 EIW74627.1 - 1.3e-21 76.9 0.0 4.7e-19 68.4 0.0 2.2 2 0 0 2 2 2 2 Interferon-inducible GTPase (IIGP) MMR_HSR1 PF01926.18 EIW74627.1 - 1.3e-09 37.9 0.0 6.5e-09 35.7 0.0 2.1 1 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EIW74627.1 - 4.1e-05 24.0 0.0 9.5e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 EIW74627.1 - 0.001 18.5 0.0 0.017 14.6 0.0 2.7 3 0 0 3 3 3 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EIW74627.1 - 0.0016 18.7 0.1 0.0016 18.7 0.1 2.8 2 2 0 2 2 2 1 ABC transporter Dynamin_N PF00350.18 EIW74627.1 - 0.0031 17.3 2.7 0.028 14.2 0.0 2.7 2 1 0 2 2 2 1 Dynamin family ATP_bind_1 PF03029.12 EIW74627.1 - 0.0057 16.2 0.1 0.85 9.1 0.1 2.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein DUF258 PF03193.11 EIW74627.1 - 0.0098 15.0 0.0 0.021 14.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EIW74627.1 - 0.013 14.8 0.0 0.02 14.1 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.1 EIW74627.1 - 0.02 15.0 0.0 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EIW74627.1 - 0.031 13.7 0.0 0.031 13.7 0.0 2.5 2 1 1 3 3 3 0 FtsK/SpoIIIE family DUF87 PF01935.12 EIW74627.1 - 0.061 13.1 0.1 0.061 13.1 0.1 2.4 2 1 0 3 3 3 0 Domain of unknown function DUF87 SMC_N PF02463.14 EIW74627.1 - 0.064 12.4 0.3 0.55 9.4 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 EIW74627.1 - 0.071 12.5 0.0 0.071 12.5 0.0 2.1 2 1 0 2 2 1 0 AAA-like domain AAA_16 PF13191.1 EIW74627.1 - 0.11 12.4 0.1 0.11 12.4 0.1 2.9 1 1 2 3 3 2 0 AAA ATPase domain Ycf1 PF05758.7 EIW74627.1 - 0.73 7.4 4.3 0.72 7.4 1.9 1.7 2 0 0 2 2 2 0 Ycf1 AAA_11 PF13086.1 EIW74627.1 - 0.74 9.3 3.8 0.51 9.8 1.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EIW74627.1 - 0.74 10.6 9.4 0.62 10.8 1.4 3.4 2 1 0 2 2 2 0 AAA domain DUF2229 PF09989.4 EIW74627.1 - 5.4 6.4 6.8 9.1 5.6 0.8 2.4 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) ATP-synt_B PF00430.13 EIW74627.1 - 7.3 6.4 28.5 0.67 9.7 8.5 2.5 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DPBB_1 PF03330.13 EIW74628.1 - 1.3e-05 25.1 0.4 2.7e-05 24.0 0.3 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIW74628.1 - 0.0032 17.1 0.2 0.0038 16.9 0.2 1.2 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.7 EIW74628.1 - 0.018 15.0 0.1 0.019 14.9 0.1 1.2 1 0 0 1 1 1 0 Cerato-platanin Filament_head PF04732.9 EIW74628.1 - 0.1 13.3 0.2 0.19 12.4 0.1 1.4 1 1 0 1 1 1 0 Intermediate filament head (DNA binding) region DPBB_1 PF03330.13 EIW74629.1 - 8.5e-06 25.6 0.2 1.4e-05 25.0 0.1 1.4 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIW74629.1 - 0.0091 15.6 0.2 0.014 15.0 0.1 1.5 1 1 0 1 1 1 1 Barwin family Ifi-6-16 PF06140.8 EIW74630.1 - 2.9e-05 23.7 8.5 3.8e-05 23.3 5.9 1.4 1 0 0 1 1 1 1 Interferon-induced 6-16 family Chorion_1 PF01723.11 EIW74630.1 - 0.24 11.2 2.7 0.27 11.1 1.8 1.0 1 0 0 1 1 1 0 Chorion protein Tim17 PF02466.14 EIW74630.1 - 0.89 9.6 5.7 1.2 9.1 3.9 1.5 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family DUF4199 PF13858.1 EIW74630.1 - 8.5 6.2 8.0 10 5.9 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Ifi-6-16 PF06140.8 EIW74631.1 - 6.2e-06 25.9 2.0 9e-06 25.3 1.4 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family DUF4133 PF13571.1 EIW74631.1 - 4.4 7.6 6.7 1.1 9.4 1.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) Ifi-6-16 PF06140.8 EIW74632.1 - 9.5e-06 25.3 12.8 1.6e-05 24.6 8.8 1.5 1 1 0 1 1 1 1 Interferon-induced 6-16 family DUF3759 PF12585.3 EIW74634.1 - 2.7e-35 120.1 6.3 3e-35 119.9 4.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF3759 PF12585.3 EIW74636.1 - 2e-33 114.1 4.6 2.1e-33 114.0 3.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) TFIIS_C PF01096.13 EIW74637.1 - 4.8e-21 74.0 1.5 4.8e-21 74.0 1.0 2.8 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EIW74637.1 - 1.6e-09 37.3 6.5 8.4e-09 34.9 0.4 3.1 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 EIW74637.1 - 2e-05 24.3 6.0 0.012 15.3 0.7 2.3 2 0 0 2 2 2 2 Transposase zinc-ribbon domain DZR PF12773.2 EIW74637.1 - 0.011 15.5 5.6 0.94 9.3 0.5 2.5 2 1 0 2 2 2 0 Double zinc ribbon Baculo_LEF5_C PF11792.3 EIW74637.1 - 0.037 13.4 1.7 0.12 11.8 0.3 2.4 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain PhnA_Zn_Ribbon PF08274.7 EIW74637.1 - 0.043 13.6 10.4 4.3 7.2 0.1 3.6 3 1 1 4 4 4 0 PhnA Zinc-Ribbon C1_1 PF00130.17 EIW74637.1 - 0.056 13.1 7.2 0.5 10.1 0.5 2.7 2 1 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Tnp_zf-ribbon_2 PF13842.1 EIW74637.1 - 0.11 12.9 7.3 10 6.6 1.2 3.3 2 1 1 3 3 3 0 DDE_Tnp_1-like zinc-ribbon PHD PF00628.24 EIW74637.1 - 0.14 11.8 10.9 0.45 10.2 0.6 3.0 2 2 0 2 2 2 0 PHD-finger DUF2387 PF09526.5 EIW74637.1 - 0.14 12.0 7.0 1.8 8.5 0.5 2.9 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) zf-TFIIB PF13453.1 EIW74637.1 - 0.22 10.7 3.0 1.3 8.2 0.1 2.8 3 0 0 3 3 3 0 Transcription factor zinc-finger Terminase_GpA PF05876.7 EIW74637.1 - 0.42 8.9 4.2 0.22 9.8 0.7 1.8 1 1 1 2 2 2 0 Phage terminase large subunit (GpA) UPF0547 PF10571.4 EIW74637.1 - 0.47 10.1 8.5 7.7 6.3 0.2 3.9 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 Zn-ribbon_8 PF09723.5 EIW74637.1 - 0.65 9.9 7.5 35 4.4 0.2 4.0 4 0 0 4 4 4 0 Zinc ribbon domain CIAPIN1 PF05093.8 EIW74637.1 - 0.91 9.6 5.6 0.72 9.9 0.6 2.1 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Copper-fist PF00649.13 EIW74637.1 - 1.5 8.1 3.9 3.1 7.0 0.7 2.5 2 0 0 2 2 2 0 Copper fist DNA binding domain IBR PF01485.16 EIW74637.1 - 2.2 8.2 8.8 2.2 8.2 0.3 3.0 2 1 0 2 2 2 0 IBR domain zf-CHY PF05495.7 EIW74637.1 - 2.2 8.4 8.7 6.7 6.9 0.9 2.7 1 1 1 2 2 2 0 CHY zinc finger HypA PF01155.14 EIW74637.1 - 2.8 7.6 6.0 1.5 8.5 1.1 2.5 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Rep_fac-A_C PF08646.5 EIW74637.1 - 2.9 7.6 6.9 1.1 8.9 0.2 2.5 1 1 2 3 3 3 0 Replication factor-A C terminal domain zinc-ribbons_6 PF07191.7 EIW74637.1 - 3 7.7 6.4 1.1 9.0 0.2 2.5 2 1 0 2 2 2 0 zinc-ribbons DUF2296 PF10058.4 EIW74637.1 - 4.3 7.1 10.1 0.49 10.1 0.7 2.9 2 2 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) C1_4 PF07975.7 EIW74637.1 - 5.2 7.1 10.1 28 4.8 2.2 3.3 1 1 2 3 3 3 0 TFIIH C1-like domain zf-AN1 PF01428.11 EIW74637.1 - 5.7 6.9 7.1 54 3.7 0.1 3.3 3 1 0 3 3 3 0 AN1-like Zinc finger DUF3716 PF12511.3 EIW74637.1 - 5.9 6.5 11.9 0.46 10.1 0.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3716) TF_Zn_Ribbon PF08271.7 EIW74637.1 - 8.6 5.7 8.2 0.69 9.2 1.2 2.4 2 1 0 2 2 2 0 TFIIB zinc-binding Rpr2 PF04032.11 EIW74637.1 - 9.3 6.2 8.6 2.4e+02 1.6 6.0 2.7 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Zn_clus PF00172.13 EIW74641.1 - 6.4e-07 29.1 9.6 1.1e-06 28.3 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3759 PF12585.3 EIW74642.1 - 1.1e-34 118.2 6.6 1.5e-34 117.7 4.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) DUF3759 PF12585.3 EIW74644.1 - 3.6e-34 116.5 7.9 6.4e-34 115.7 5.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) bZIP_1 PF00170.16 EIW74645.1 - 2.7e-08 33.6 12.7 9e-08 31.9 6.8 2.1 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EIW74645.1 - 2.2e-05 24.1 11.0 2.2e-05 24.1 7.6 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EIW74645.1 - 0.43 10.9 11.1 0.27 11.5 6.2 1.7 1 1 0 1 1 1 0 bZIP Maf transcription factor SAA PF00277.13 EIW74646.1 - 0.42 11.0 4.1 0.77 10.1 1.0 2.2 2 0 0 2 2 2 0 Serum amyloid A protein DUF3759 PF12585.3 EIW74647.1 - 1.6e-35 120.8 5.6 1.9e-35 120.6 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) SPRY PF00622.23 EIW74648.1 - 3.2e-12 46.6 0.0 5.7e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Zn_clus PF00172.13 EIW74649.1 - 0.0058 16.5 11.9 0.01 15.7 1.4 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 EIW74650.1 - 7.3e-33 111.2 0.2 4.9e-10 38.8 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EIW74650.1 - 8.4e-05 21.0 0.0 0.00026 19.3 0.0 1.7 2 0 0 2 2 2 1 Cytochrome D1 heme domain PQQ_2 PF13360.1 EIW74650.1 - 0.00011 21.7 0.0 0.0019 17.6 0.0 2.1 1 1 1 2 2 2 1 PQQ-like domain Nup160 PF11715.3 EIW74650.1 - 0.0012 17.0 0.0 0.002 16.3 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIW74650.1 - 0.0018 17.0 0.1 0.37 9.4 0.0 2.2 1 1 1 2 2 2 2 Nup133 N terminal like eIF2A PF08662.6 EIW74650.1 - 0.012 15.2 0.3 1.9 8.1 0.0 2.6 2 2 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A Ebp2 PF05890.7 EIW74651.1 - 3.1e-76 256.2 17.0 4.4e-76 255.7 11.8 1.2 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Actin PF00022.14 EIW74652.1 - 1.1e-75 254.5 0.0 1.3e-75 254.3 0.0 1.0 1 0 0 1 1 1 1 Actin NRDE PF05742.7 EIW74653.1 - 1.2e-35 123.1 0.0 2e-22 79.7 0.0 3.0 2 1 0 2 2 2 2 NRDE protein UPF0227 PF05728.7 EIW74653.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Zn_clus PF00172.13 EIW74654.1 - 2.5e-08 33.6 7.2 2.5e-08 33.6 5.0 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MGC-24 PF05283.6 EIW74654.1 - 0.34 10.6 3.1 1.3 8.8 0.1 2.2 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) PSS PF03034.10 EIW74655.1 - 9.3e-100 333.6 9.3 1.2e-99 333.2 6.5 1.1 1 0 0 1 1 1 1 Phosphatidyl serine synthase HNH_2 PF13391.1 EIW74656.1 - 2.3e-07 30.5 1.4 0.00032 20.4 0.1 3.1 3 0 0 3 3 3 2 HNH endonuclease Metallophos PF00149.23 EIW74656.1 - 0.0089 15.4 0.6 0.029 13.7 0.3 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Asp PF00026.18 EIW74658.1 - 3.7e-13 49.4 0.2 9.3e-12 44.8 0.2 2.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Podoplanin PF05808.6 EIW74658.1 - 0.0015 18.1 0.0 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 Podoplanin Asp_protease_2 PF13650.1 EIW74658.1 - 0.0087 16.5 0.6 0.14 12.6 0.0 3.1 3 1 0 3 3 3 1 Aspartyl protease DAP10 PF07213.6 EIW74658.1 - 0.011 15.4 0.1 0.03 14.0 0.1 1.8 1 0 0 1 1 1 0 DAP10 membrane protein Shisa PF13908.1 EIW74658.1 - 0.072 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Amastin PF07344.6 EIW74658.1 - 0.074 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Amastin surface glycoprotein zf-DHHC PF01529.15 EIW74659.1 - 6.5e-32 110.3 8.5 6.5e-32 110.3 5.9 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase Oleosin PF01277.12 EIW74659.1 - 3.6 7.1 5.9 2.9 7.4 2.0 2.1 2 0 0 2 2 2 0 Oleosin Methyltransf_33 PF10017.4 EIW74660.1 - 3.9e-35 120.4 0.4 8e-35 119.4 0.3 1.5 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EIW74660.1 - 3.3e-24 85.6 1.5 4.5e-13 49.1 0.0 2.2 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EIW74660.1 - 6.2e-08 33.0 0.7 1.4e-07 31.8 0.5 1.6 1 0 0 1 1 1 1 DinB superfamily AAA_16 PF13191.1 EIW74661.1 - 4.9e-09 36.4 0.1 6.7e-09 35.9 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EIW74661.1 - 5.5e-09 35.8 0.0 8.5e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain APS_kinase PF01583.15 EIW74661.1 - 0.00061 19.4 0.0 0.00081 19.0 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.1 EIW74661.1 - 0.00075 19.6 0.0 0.0011 19.1 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW74661.1 - 0.00086 20.1 0.1 0.0014 19.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIW74661.1 - 0.0022 18.3 0.0 0.0036 17.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EIW74661.1 - 0.007 16.5 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 RNA helicase Cytidylate_kin2 PF13189.1 EIW74661.1 - 0.011 15.6 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family PRK PF00485.13 EIW74661.1 - 0.015 14.8 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 EIW74661.1 - 0.03 13.3 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.1 EIW74661.1 - 0.043 13.3 0.1 0.11 11.9 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SE PF00437.15 EIW74661.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_31 PF13614.1 EIW74661.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EIW74661.1 - 0.15 11.7 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 NTPase WD40 PF00400.27 EIW74662.1 - 4.4e-23 80.2 9.3 6.4e-06 25.8 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Kazal_2 PF07648.10 EIW74662.1 - 0.037 13.9 0.1 0.096 12.6 0.0 1.6 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Omega-toxin PF06357.6 EIW74662.1 - 0.12 11.9 0.7 0.28 10.8 0.5 1.6 1 0 0 1 1 1 0 Omega-atracotoxin DUF2419 PF10343.4 EIW74667.1 - 3e-80 269.5 0.0 1.3e-49 169.0 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF2419) TMF_DNA_bd PF12329.3 EIW74669.1 - 0.003 17.3 12.4 0.0054 16.5 3.0 2.9 2 1 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Baculo_PEP_C PF04513.7 EIW74669.1 - 0.041 13.7 3.4 7.5 6.3 0.5 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EIW74669.1 - 0.046 12.9 5.8 1 8.5 0.2 2.2 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF972 PF06156.8 EIW74669.1 - 0.54 10.6 11.9 3.7 7.9 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) RRN3 PF05327.6 EIW74669.1 - 0.97 7.4 5.9 1.4 6.9 4.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1664 PF07889.7 EIW74669.1 - 5.6 6.7 10.2 0.32 10.7 1.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) FAM178 PF14816.1 EIW74669.1 - 7.5 5.1 10.8 7.6 5.1 0.3 2.2 2 0 0 2 2 2 0 Family of unknown function, FAM178 DUF2422 PF10337.4 EIW74669.1 - 7.6 5.1 6.0 4.4 5.9 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) NMD3 PF04981.8 EIW74670.1 - 2.7e-09 36.4 0.3 4.3e-07 29.3 0.0 2.2 1 1 1 2 2 2 2 NMD3 family Trypan_PARP PF05887.6 EIW74672.1 - 0.0023 17.7 17.0 0.0044 16.8 11.8 1.4 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) ORC6 PF05460.8 EIW74672.1 - 0.45 9.5 7.5 0.59 9.1 5.2 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) AF1Q PF15017.1 EIW74672.1 - 0.84 9.5 0.0 0.84 9.5 0.0 3.3 3 1 0 3 3 3 0 Drug resistance and apoptosis regulator BUD22 PF09073.5 EIW74672.1 - 6.6 5.6 13.6 0.19 10.7 4.8 1.7 2 0 0 2 2 2 0 BUD22 Cauli_VI PF01693.11 EIW74673.1 - 0.0071 16.3 0.1 0.013 15.4 0.1 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF605 PF04652.11 EIW74673.1 - 2.3 7.5 7.2 3.8 6.8 5.0 1.4 1 0 0 1 1 1 0 Vta1 like zf-B_box PF00643.19 EIW74674.1 - 0.00064 19.5 4.8 0.0024 17.7 3.3 1.9 1 0 0 1 1 1 1 B-box zinc finger MAD PF05557.8 EIW74674.1 - 0.082 10.9 0.9 0.12 10.4 0.7 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein UBN2_3 PF14244.1 EIW74676.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.4 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type DNA_pol_B_palm PF14792.1 EIW74677.1 - 2.7e-16 59.6 0.0 8.1e-09 35.5 0.0 2.6 2 0 0 2 2 2 2 DNA polymerase beta palm HHH_8 PF14716.1 EIW74677.1 - 3.7e-15 55.8 0.1 1.6e-12 47.4 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix domain DNA_pol_B_thumb PF14791.1 EIW74677.1 - 2.9e-13 49.2 0.1 5.8e-13 48.3 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 EIW74677.1 - 4e-06 26.2 0.0 7.5e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 EIW74677.1 - 4.9e-05 23.4 0.0 0.00017 21.6 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.18 EIW74677.1 - 0.00012 21.6 0.0 0.0019 17.8 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif NTP_transf_2 PF01909.18 EIW74677.1 - 0.00087 19.5 0.0 0.0021 18.3 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH_2 PF12826.2 EIW74677.1 - 0.014 15.2 0.0 0.49 10.3 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif Cdd1 PF11731.3 EIW74677.1 - 0.02 14.8 0.0 0.045 13.6 0.0 1.6 1 1 0 1 1 1 0 Pathogenicity locus HHH_3 PF12836.2 EIW74677.1 - 0.13 12.2 0.0 1.6 8.7 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif AT_hook PF02178.14 EIW74677.1 - 5 7.1 16.1 3.9 7.4 1.7 4.1 3 0 0 3 3 3 0 AT hook motif SNF5 PF04855.7 EIW74678.1 - 2e-54 184.6 0.0 1.8e-49 168.4 0.0 2.3 2 0 0 2 2 2 2 SNF5 / SMARCB1 / INI1 DUF1421 PF07223.6 EIW74678.1 - 4 7.1 41.0 1.3 8.7 26.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1421) zf-C2H2 PF00096.21 EIW74680.1 - 1.8e-08 34.2 9.2 0.00039 20.5 1.1 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW74680.1 - 8.5e-08 32.1 16.6 2.2e-06 27.6 1.9 3.6 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIW74680.1 - 1.6e-06 28.0 9.5 0.0089 16.2 1.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger Asp_protease_2 PF13650.1 EIW74681.1 - 0.00054 20.4 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease Chromo PF00385.19 EIW74683.1 - 1.4e-08 34.2 1.1 1.9e-08 33.8 0.8 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EIW74683.1 - 0.075 12.7 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Peptidase_M20 PF01546.23 EIW74684.1 - 1.6 8.1 4.9 1.7 8.0 3.4 1.0 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Rad50_zn_hook PF04423.9 EIW74685.1 - 0.55 9.7 4.4 0.44 10.0 1.4 2.0 2 0 0 2 2 2 0 Rad50 zinc hook motif Cauli_VI PF01693.11 EIW74686.1 - 0.002 18.0 0.0 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin HMG_box_2 PF09011.5 EIW74686.1 - 0.0025 18.1 0.1 0.0064 16.8 0.1 1.6 1 0 0 1 1 1 1 HMG-box domain DUF2486 PF10667.4 EIW74687.1 - 0.19 12.2 5.1 0.22 12.0 3.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) Dynactin_p62 PF05502.8 EIW74689.1 - 3.6e-90 303.0 2.0 2e-88 297.2 1.4 2.1 1 1 0 1 1 1 1 Dynactin p62 family YndJ PF14158.1 EIW74690.1 - 0.19 10.7 0.0 0.29 10.1 0.0 1.1 1 0 0 1 1 1 0 YndJ-like protein Heme_oxygenase PF01126.15 EIW74695.1 - 4.8e-32 111.2 0.0 8.7e-32 110.3 0.0 1.4 1 1 0 1 1 1 1 Heme oxygenase Heme_oxygenase PF01126.15 EIW74696.1 - 9.9e-30 103.6 0.0 1.9e-16 60.2 0.0 2.1 2 0 0 2 2 2 2 Heme oxygenase Asp PF00026.18 EIW74697.1 - 8.6e-21 74.4 5.7 1.8e-18 66.8 4.0 2.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EIW74697.1 - 7.5e-05 23.1 2.3 0.00034 21.0 0.3 2.9 3 2 0 3 3 3 1 Aspartyl protease Herpes_gE PF02480.11 EIW74697.1 - 0.0006 18.1 0.1 0.0011 17.3 0.1 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1183 PF06682.7 EIW74697.1 - 0.0055 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Orthoreo_P10 PF07204.6 EIW74697.1 - 0.0087 15.7 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 TAXi_N PF14543.1 EIW74697.1 - 0.043 13.7 2.1 0.92 9.4 1.2 2.5 1 1 0 1 1 1 0 Xylanase inhibitor N-terminal Asp PF00026.18 EIW74698.1 - 6.1e-16 58.5 0.4 2.7e-14 53.1 0.0 2.7 1 1 1 2 2 2 2 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EIW74698.1 - 7.6e-07 29.5 0.1 0.0084 16.5 0.1 2.9 2 1 0 2 2 2 2 Aspartyl protease DUF1183 PF06682.7 EIW74698.1 - 9.6e-06 25.4 0.3 1.9e-05 24.4 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Herpes_gE PF02480.11 EIW74698.1 - 0.0026 16.0 0.0 0.0039 15.5 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E gag-asp_proteas PF13975.1 EIW74698.1 - 0.004 16.9 0.1 0.0089 15.8 0.1 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease Adeno_E3_CR2 PF02439.10 EIW74698.1 - 0.0073 15.8 0.8 0.012 15.1 0.5 1.3 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 VSP PF03302.8 EIW74698.1 - 0.0099 14.5 0.1 0.014 14.0 0.0 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF912 PF06024.7 EIW74698.1 - 0.026 14.5 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Shisa PF13908.1 EIW74698.1 - 0.044 13.9 0.0 0.075 13.1 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TMEM154 PF15102.1 EIW74698.1 - 0.053 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 TMEM154 protein family NACHT PF05729.7 EIW74700.1 - 5.6e-07 29.3 0.0 2.1e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW74700.1 - 5.8e-05 23.1 0.0 7.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EIW74700.1 - 0.0016 18.1 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain ResIII PF04851.10 EIW74700.1 - 0.003 17.4 0.0 0.0042 16.9 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit APS_kinase PF01583.15 EIW74700.1 - 0.0041 16.7 0.1 0.007 16.0 0.1 1.4 1 1 0 1 1 1 1 Adenylylsulphate kinase NB-ARC PF00931.17 EIW74700.1 - 0.0057 15.5 0.0 0.0088 14.9 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain Arch_ATPase PF01637.13 EIW74700.1 - 0.014 15.0 0.0 0.019 14.6 0.0 1.1 1 0 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 EIW74700.1 - 0.015 15.4 0.0 0.029 14.5 0.0 1.4 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EIW74700.1 - 0.02 14.4 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF2075 PF09848.4 EIW74700.1 - 0.021 13.8 0.0 0.028 13.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.4 EIW74700.1 - 0.031 12.8 0.0 0.043 12.4 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.24 EIW74700.1 - 0.032 14.4 0.0 0.054 13.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.9 EIW74700.1 - 0.037 12.9 0.0 0.047 12.6 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase DUF815 PF05673.8 EIW74700.1 - 0.047 12.5 0.0 0.06 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.8 EIW74700.1 - 0.064 11.9 0.0 0.082 11.6 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus Torsin PF06309.6 EIW74700.1 - 0.087 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_30 PF13604.1 EIW74700.1 - 0.089 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EIW74700.1 - 0.098 12.2 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EIW74700.1 - 0.11 11.3 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 zf-CCCH PF00642.19 EIW74701.1 - 9.2e-13 47.5 25.9 1.2e-05 24.8 4.4 3.3 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) LRV_FeS PF05484.6 EIW74701.1 - 0.023 14.2 6.6 0.081 12.5 0.4 3.1 3 0 0 3 3 3 0 LRV protein FeS4 cluster zf-CCCH_2 PF14608.1 EIW74701.1 - 6.2 6.9 20.0 3.8 7.6 1.7 3.7 3 1 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type zf-RING_2 PF13639.1 EIW74702.1 - 3.6e-14 52.3 2.0 8.9e-14 51.0 1.4 1.7 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EIW74702.1 - 1.2e-10 41.0 0.0 2.1e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 PA domain zf-RING_5 PF14634.1 EIW74702.1 - 8.7e-06 25.3 1.1 1.6e-05 24.5 0.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EIW74702.1 - 2.1e-05 24.5 4.7 5.3e-05 23.2 3.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EIW74702.1 - 2.1e-05 24.4 2.4 5.8e-05 23.0 1.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW74702.1 - 9.3e-05 22.0 1.6 0.00019 20.9 1.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW74702.1 - 0.00012 21.6 1.0 0.00025 20.6 0.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIW74702.1 - 0.058 13.2 1.2 0.19 11.5 0.8 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SapB_1 PF05184.10 EIW74702.1 - 0.74 9.7 0.0 0.74 9.7 0.0 2.4 3 0 0 3 3 3 0 Saposin-like type B, region 1 FANCL_C PF11793.3 EIW74702.1 - 0.75 9.7 3.9 4.7 7.2 1.8 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain zf-C2H2_4 PF13894.1 EIW74703.1 - 0.00019 21.4 12.0 0.018 15.3 0.2 3.7 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIW74703.1 - 0.0073 16.5 9.0 0.17 12.3 1.6 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EIW74703.1 - 0.22 11.7 2.8 9.9 6.4 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-HYPF PF07503.7 EIW74703.1 - 0.77 9.2 4.7 0.32 10.4 1.0 2.0 2 0 0 2 2 2 0 HypF finger zf-H2C2_2 PF13465.1 EIW74703.1 - 2.9 8.3 5.8 3.9 7.9 2.0 2.6 2 0 0 2 2 2 0 Zinc-finger double domain NACHT PF05729.7 EIW74704.1 - 1.4e-12 47.6 0.0 2.1e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW74704.1 - 1.5e-07 31.6 0.0 3.9e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EIW74704.1 - 2e-05 24.8 0.0 0.00035 20.7 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EIW74704.1 - 0.00016 21.3 0.0 0.00036 20.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EIW74704.1 - 0.00018 21.6 0.0 0.0036 17.4 0.0 2.7 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.1 EIW74704.1 - 0.00075 18.9 0.0 0.0047 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EIW74704.1 - 0.0019 17.2 0.0 0.075 12.0 0.0 2.1 2 0 0 2 2 2 1 KAP family P-loop domain RNA_helicase PF00910.17 EIW74704.1 - 0.0027 17.8 0.0 0.008 16.3 0.0 1.8 1 0 0 1 1 1 1 RNA helicase AAA_11 PF13086.1 EIW74704.1 - 0.0029 17.2 0.0 0.0044 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW74704.1 - 0.0041 17.0 0.0 0.0073 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW74704.1 - 0.0042 17.8 0.0 0.014 16.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EIW74704.1 - 0.008 15.9 0.0 0.041 13.5 0.0 2.2 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 EIW74704.1 - 0.012 14.6 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) APS_kinase PF01583.15 EIW74704.1 - 0.014 15.1 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase TIP49 PF06068.8 EIW74704.1 - 0.016 13.9 0.0 0.022 13.5 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus RuvB_N PF05496.7 EIW74704.1 - 0.031 13.3 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EIW74704.1 - 0.032 13.6 0.0 0.085 12.2 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein PhoH PF02562.11 EIW74704.1 - 0.037 13.2 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.1 EIW74704.1 - 0.04 14.2 0.0 0.081 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 EIW74704.1 - 0.069 13.0 0.0 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Torsin AAA_30 PF13604.1 EIW74704.1 - 0.073 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EIW74704.1 - 0.18 10.6 0.0 0.32 9.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_16 PF13191.1 EIW74705.1 - 1.1e-06 28.8 0.1 1.7e-06 28.1 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EIW74705.1 - 1e-05 25.2 0.0 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EIW74705.1 - 0.00051 20.1 0.0 0.0022 18.1 0.0 1.8 1 1 1 2 2 2 1 AAA domain NB-ARC PF00931.17 EIW74705.1 - 0.00053 18.9 0.0 0.00061 18.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain ResIII PF04851.10 EIW74705.1 - 0.00057 19.7 0.0 0.00078 19.3 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 EIW74705.1 - 0.0015 18.3 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_19 PF13245.1 EIW74705.1 - 0.0022 17.6 0.0 0.0056 16.4 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain Parvo_NS1 PF01057.12 EIW74705.1 - 0.0059 15.5 0.0 0.008 15.0 0.0 1.1 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 DUF2075 PF09848.4 EIW74705.1 - 0.0071 15.3 0.0 0.0082 15.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 EIW74705.1 - 0.019 15.1 0.0 0.027 14.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PIF1 PF05970.9 EIW74705.1 - 0.021 13.7 0.0 0.027 13.4 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase APS_kinase PF01583.15 EIW74705.1 - 0.023 14.3 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase TIP49 PF06068.8 EIW74705.1 - 0.024 13.3 0.0 0.031 12.9 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus UPF0079 PF02367.12 EIW74705.1 - 0.033 13.8 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 TrwB_AAD_bind PF10412.4 EIW74705.1 - 0.038 12.6 0.0 0.091 11.3 0.0 1.6 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_11 PF13086.1 EIW74705.1 - 0.038 13.5 0.0 0.08 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain L6_membrane PF05805.7 EIW74705.1 - 0.039 13.5 0.0 0.047 13.2 0.0 1.1 1 0 0 1 1 1 0 L6 membrane protein Torsin PF06309.6 EIW74705.1 - 0.057 13.2 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 Torsin Glycos_transf_N PF04413.11 EIW74705.1 - 0.059 12.5 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) DUF815 PF05673.8 EIW74705.1 - 0.091 11.6 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) T2SE PF00437.15 EIW74705.1 - 0.091 11.6 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 EIW74705.1 - 0.13 11.4 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein RNA_helicase PF00910.17 EIW74705.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 EIW74706.1 - 2.4e-06 27.3 0.0 4.5e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 EIW74706.1 - 3.1e-06 27.0 0.0 6.1e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase AAA PF00004.24 EIW74706.1 - 0.00021 21.5 0.0 0.0027 17.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EIW74706.1 - 0.00027 20.4 0.0 0.00076 18.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW74706.1 - 0.00086 19.3 0.0 0.0024 17.8 0.0 2.0 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW74706.1 - 0.00099 19.2 0.0 0.0045 17.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain PIF1 PF05970.9 EIW74706.1 - 0.0037 16.2 0.0 0.0049 15.8 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_19 PF13245.1 EIW74706.1 - 0.0057 16.3 1.4 0.029 14.1 1.0 2.2 1 1 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EIW74706.1 - 0.0071 15.9 0.0 0.0085 15.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EIW74706.1 - 0.0072 16.4 0.0 0.025 14.7 0.0 1.9 2 0 0 2 2 1 1 RNA helicase TIP49 PF06068.8 EIW74706.1 - 0.0078 14.9 0.0 0.012 14.3 0.0 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 EIW74706.1 - 0.011 15.4 0.0 0.037 13.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EIW74706.1 - 0.012 16.4 0.1 0.03 15.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain ResIII PF04851.10 EIW74706.1 - 0.019 14.7 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_14 PF13173.1 EIW74706.1 - 0.025 14.4 0.0 11 5.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain IPT PF01745.11 EIW74706.1 - 0.032 13.4 0.1 0.084 12.0 0.0 1.7 2 0 0 2 2 2 0 Isopentenyl transferase AAA_18 PF13238.1 EIW74706.1 - 0.036 14.3 0.0 0.059 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EIW74706.1 - 0.041 13.1 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.12 EIW74706.1 - 0.05 13.0 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein APS_kinase PF01583.15 EIW74706.1 - 0.053 13.1 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase RuvB_N PF05496.7 EIW74706.1 - 0.1 11.6 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus KAP_NTPase PF07693.9 EIW74706.1 - 0.11 11.5 0.0 3 6.7 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain Parvo_NS1 PF01057.12 EIW74706.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 EIW74706.1 - 0.15 11.6 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 A_deaminase PF00962.17 EIW74707.1 - 3.7e-51 174.0 0.0 6.1e-51 173.2 0.0 1.3 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 EIW74707.1 - 0.00079 19.4 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal Peptidase_M48 PF01435.13 EIW74707.1 - 0.13 11.8 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M48 Pro_dh PF01619.13 EIW74708.1 - 2.7e-35 121.8 0.0 7.7e-33 113.7 0.0 3.7 1 1 0 1 1 1 1 Proline dehydrogenase Choline_sulf_C PF12411.3 EIW74709.1 - 0.15 11.9 0.4 11 5.9 0.1 2.2 2 0 0 2 2 2 0 Choline sulfatase enzyme C terminal Glyco_hydro_15 PF00723.16 EIW74710.1 - 2.2e-94 316.5 0.0 2.6e-94 316.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EIW74710.1 - 2.8e-26 90.9 1.4 6.4e-26 89.8 0.9 1.6 1 0 0 1 1 1 1 Starch binding domain DUF500 PF04366.7 EIW74715.1 - 3.5e-45 152.5 0.0 6e-45 151.7 0.0 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF500) Phosphodiest PF01663.17 EIW74716.1 - 6.3e-72 242.9 0.1 7.7e-72 242.6 0.1 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Phosphodiest PF01663.17 EIW74717.1 - 2.2e-73 247.7 1.0 2.7e-73 247.3 0.7 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Peptidase_S32 PF05579.8 EIW74718.1 - 0.00012 21.1 0.0 0.0002 20.4 0.0 1.3 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Peptidase_S29 PF02907.10 EIW74718.1 - 0.025 14.1 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Peptidase_S7 PF00949.16 EIW74718.1 - 0.12 11.8 0.2 0.25 10.7 0.1 1.5 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Prenyltransf PF01255.14 EIW74719.1 - 1.2e-73 246.8 0.0 1.7e-73 246.4 0.0 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase AAA_5 PF07728.9 EIW74720.1 - 1.2e-118 391.1 0.0 7.2e-20 71.1 0.0 10.6 11 0 0 11 11 10 9 AAA domain (dynein-related subfamily) AAA PF00004.24 EIW74720.1 - 1.2e-24 86.9 0.4 8.4e-05 22.7 0.0 7.0 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 EIW74720.1 - 1.2e-23 83.1 0.0 7.3e-09 35.3 0.0 7.0 7 0 0 7 7 7 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIW74720.1 - 2.9e-21 75.9 0.3 0.011 15.8 0.0 7.4 6 0 0 6 6 6 4 AAA domain AAA_17 PF13207.1 EIW74720.1 - 9.8e-20 71.5 0.6 0.0083 16.9 0.0 7.0 6 0 0 6 6 6 4 AAA domain Sigma54_activ_2 PF14532.1 EIW74720.1 - 4.9e-17 62.2 0.1 0.0038 17.2 0.0 6.5 6 0 0 6 6 6 3 Sigma-54 interaction domain AAA_18 PF13238.1 EIW74720.1 - 1.8e-16 60.6 1.4 0.034 14.4 0.0 7.1 6 0 0 6 6 6 4 AAA domain T2SE PF00437.15 EIW74720.1 - 1.9e-15 56.5 0.0 0.0046 15.9 0.0 6.2 6 0 0 6 6 6 4 Type II/IV secretion system protein Sigma54_activat PF00158.21 EIW74720.1 - 1.9e-15 56.7 0.0 0.02 14.3 0.0 6.3 6 0 0 6 6 6 3 Sigma-54 interaction domain AAA_16 PF13191.1 EIW74720.1 - 1e-13 51.6 21.2 0.0029 17.6 0.2 9.4 8 2 0 8 8 7 3 AAA ATPase domain AAA_14 PF13173.1 EIW74720.1 - 3.3e-13 49.6 0.0 0.0014 18.5 0.0 6.7 6 0 0 6 6 6 2 AAA domain AAA_33 PF13671.1 EIW74720.1 - 1.2e-12 47.8 0.4 0.13 12.1 0.0 6.6 5 1 0 5 5 5 2 AAA domain Zeta_toxin PF06414.7 EIW74720.1 - 1.6e-12 46.9 0.0 0.32 10.0 0.0 7.7 8 0 0 8 8 8 2 Zeta toxin UPF0079 PF02367.12 EIW74720.1 - 1.1e-11 44.4 1.1 0.15 11.6 0.0 5.5 5 0 0 5 5 5 3 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EIW74720.1 - 1.2e-11 44.1 13.3 0.0037 16.9 0.5 6.8 6 0 0 6 6 6 3 Part of AAA domain ABC_tran PF00005.22 EIW74720.1 - 2e-09 37.8 0.1 0.85 9.9 0.0 6.3 6 0 0 6 6 6 1 ABC transporter MobB PF03205.9 EIW74720.1 - 4.2e-09 36.2 1.0 0.36 10.5 0.0 5.6 5 0 0 5 5 5 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EIW74720.1 - 1e-08 34.5 1.1 1.3 8.5 0.1 5.8 6 0 0 6 6 6 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 EIW74720.1 - 1.1e-07 31.9 0.2 7.3 6.8 0.0 6.6 6 0 0 6 6 6 0 RNA helicase AAA_28 PF13521.1 EIW74720.1 - 2.3e-07 30.9 9.9 1 9.3 0.0 6.2 6 0 0 6 6 5 2 AAA domain Miro PF08477.8 EIW74720.1 - 8.6e-07 29.4 0.3 18 5.8 0.0 5.7 5 0 0 5 5 5 0 Miro-like protein DUF815 PF05673.8 EIW74720.1 - 9.1e-07 28.0 0.1 2.3 7.1 0.0 4.8 5 0 0 5 5 5 1 Protein of unknown function (DUF815) NACHT PF05729.7 EIW74720.1 - 1.3e-06 28.1 4.9 1.3 8.7 0.0 5.0 4 0 0 4 4 4 1 NACHT domain Mg_chelatase PF01078.16 EIW74720.1 - 4.4e-06 26.0 3.3 12 4.9 0.0 7.6 9 0 0 9 9 7 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EIW74720.1 - 1.7e-05 24.3 3.3 0.87 8.9 0.0 6.0 6 0 0 6 6 6 1 AAA domain DUF258 PF03193.11 EIW74720.1 - 4.6e-05 22.6 0.0 3.3 6.8 0.0 5.0 6 0 0 6 6 5 0 Protein of unknown function, DUF258 RuvB_N PF05496.7 EIW74720.1 - 7.5e-05 21.8 0.1 4.1 6.3 0.0 5.1 6 0 0 6 6 6 0 Holliday junction DNA helicase ruvB N-terminus PduV-EutP PF10662.4 EIW74720.1 - 0.00013 21.4 0.9 2.7 7.4 0.0 4.4 4 0 0 4 4 4 1 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.12 EIW74720.1 - 0.00019 20.9 0.7 7.5 5.9 0.0 5.0 5 0 0 5 5 5 0 IstB-like ATP binding protein NTPase_1 PF03266.10 EIW74720.1 - 0.0011 18.7 6.1 1.2 8.8 0.2 4.9 4 0 0 4 4 4 1 NTPase SRP54 PF00448.17 EIW74720.1 - 0.0012 18.3 3.3 4.1 6.8 0.1 4.7 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain ResIII PF04851.10 EIW74720.1 - 0.0044 16.8 0.1 8.3 6.1 0.1 4.1 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit CPT PF07931.7 EIW74720.1 - 0.0048 16.5 1.5 1.9 8.0 0.0 5.0 6 0 0 6 6 5 1 Chloramphenicol phosphotransferase-like protein Dynein_heavy PF03028.10 EIW74720.1 - 0.0051 14.9 0.0 6.4 4.6 0.0 4.0 4 0 0 4 4 4 0 Dynein heavy chain and region D6 of dynein motor AAA_24 PF13479.1 EIW74720.1 - 0.0096 15.5 0.3 44 3.5 0.0 4.5 5 0 0 5 5 4 0 AAA domain Viral_helicase1 PF01443.13 EIW74720.1 - 0.02 14.4 0.1 1 8.8 0.0 3.7 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase cobW PF02492.14 EIW74720.1 - 0.022 14.2 7.1 15 5.0 0.0 5.3 6 0 0 6 6 6 0 CobW/HypB/UreG, nucleotide-binding domain DEAD PF00270.24 EIW74720.1 - 0.067 12.6 4.8 5.8 6.3 0.0 4.5 5 0 0 5 5 4 0 DEAD/DEAH box helicase Rad17 PF03215.10 EIW74720.1 - 0.088 11.4 0.2 63 2.0 0.0 4.2 5 0 0 5 5 5 0 Rad17 cell cycle checkpoint protein CbiA PF01656.18 EIW74720.1 - 0.11 11.8 1.9 0.98 8.7 0.0 3.0 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain VirE PF05272.6 EIW74720.1 - 0.14 11.6 0.0 9.7 5.6 0.0 3.6 4 0 0 4 4 4 0 Virulence-associated protein E AAA_6 PF12774.2 EIW74720.1 - 0.16 11.4 0.0 22 4.4 0.0 3.4 3 1 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region D1 vWA-TerF-like PF10138.4 EIW74720.1 - 0.18 11.6 0.1 0.37 10.5 0.1 1.5 1 0 0 1 1 1 0 vWA found in TerF C terminus Bac_DnaA PF00308.13 EIW74720.1 - 0.2 11.2 0.8 56 3.2 0.0 4.1 5 0 0 5 5 4 0 Bacterial dnaA protein PhoH PF02562.11 EIW74720.1 - 0.28 10.3 3.1 33 3.6 0.0 3.9 4 0 0 4 4 4 0 PhoH-like protein ArgK PF03308.11 EIW74720.1 - 0.35 9.5 1.6 7.4 5.2 0.1 3.0 3 0 0 3 3 3 0 ArgK protein TIP49 PF06068.8 EIW74720.1 - 0.35 9.5 1.3 52 2.3 0.1 3.7 4 0 0 4 4 4 0 TIP49 C-terminus KTI12 PF08433.5 EIW74720.1 - 0.55 9.4 2.1 88 2.1 0.0 4.4 5 0 0 5 5 4 0 Chromatin associated protein KTI12 AAA_7 PF12775.2 EIW74720.1 - 1 8.4 0.1 8.7 5.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region D3 MMR_HSR1 PF01926.18 EIW74720.1 - 1 9.3 3.1 13 5.7 0.0 4.3 6 0 0 6 6 4 0 50S ribosome-binding GTPase AAA_23 PF13476.1 EIW74720.1 - 2.6 8.3 19.8 9.5 6.4 0.2 6.1 6 0 0 6 6 5 0 AAA domain KaiC PF06745.8 EIW74720.1 - 2.7 7.0 5.5 20 4.2 0.2 3.8 5 0 0 5 5 4 0 KaiC DUF475 PF04332.10 EIW74720.1 - 3.9 6.9 0.2 6.8 6.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF475) DUF3605 PF12239.3 EIW74721.1 - 2.1e-25 89.4 0.1 9.8e-09 35.2 0.1 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF3605) LRR_6 PF13516.1 EIW74722.1 - 7.2e-08 31.7 3.2 2.7 8.3 0.0 7.2 7 0 0 7 7 7 2 Leucine Rich repeat LRR_4 PF12799.2 EIW74722.1 - 3e-05 23.5 6.3 0.16 11.6 0.4 5.3 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW74722.1 - 8e-05 22.3 0.5 17 5.2 0.0 5.6 6 0 0 6 6 6 1 Leucine rich repeat LRR_1 PF00560.28 EIW74722.1 - 0.0079 16.0 1.8 25 5.4 0.1 5.1 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_7 PF13504.1 EIW74722.1 - 1.5 9.3 4.9 1.4e+02 3.3 0.2 4.8 5 0 0 5 5 5 0 Leucine rich repeat Flavoprotein PF02441.14 EIW74723.1 - 2e-42 143.8 0.0 2.6e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Flavoprotein Peptidase_M36 PF02128.10 EIW74725.1 - 8.3e-78 261.8 5.5 1.6e-76 257.6 3.8 2.8 1 1 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EIW74725.1 - 0.00025 20.4 0.2 0.00053 19.4 0.2 1.5 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_MA_2 PF13485.1 EIW74725.1 - 0.012 15.6 0.1 0.026 14.5 0.1 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily Hydrolase_4 PF12146.3 EIW74725.1 - 0.078 12.8 0.3 0.25 11.2 0.1 1.9 2 0 0 2 2 2 0 Putative lysophospholipase Peptidase_M36 PF02128.10 EIW74726.1 - 2.4e-82 276.8 3.9 1.1e-80 271.3 2.7 2.8 1 1 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EIW74726.1 - 2.9e-05 23.4 0.2 6.6e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_MA_2 PF13485.1 EIW74726.1 - 0.014 15.4 0.0 0.039 13.9 0.0 1.8 1 0 0 1 1 1 0 Peptidase MA superfamily Mob1_phocein PF03637.12 EIW74727.1 - 4.3e-66 221.8 1.5 5.5e-66 221.5 1.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family zf-B_box PF00643.19 EIW74729.1 - 0.57 10.1 4.0 2.1 8.2 2.8 2.1 1 1 0 1 1 1 0 B-box zinc finger DUF2981 PF11200.3 EIW74731.1 - 0.0058 15.7 2.4 0.0091 15.1 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2981) Methyltransf_10 PF05971.7 EIW74733.1 - 8.1e-68 228.7 0.0 1.1e-67 228.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_18 PF12847.2 EIW74733.1 - 1.7e-07 31.7 0.0 7.8e-07 29.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW74733.1 - 5e-07 29.7 0.0 1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW74733.1 - 0.00022 20.6 0.0 0.00043 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EIW74733.1 - 0.00062 19.3 0.0 0.00099 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EIW74733.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) UPF0020 PF01170.13 EIW74733.1 - 0.044 13.3 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 2_5_RNA_ligase2 PF13563.1 EIW74733.1 - 0.096 12.4 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 2'-5' RNA ligase superfamily MFS_1 PF07690.11 EIW74735.1 - 4.8e-22 78.1 14.1 1.5e-13 50.2 2.8 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily FixP_N PF14715.1 EIW74735.1 - 0.0011 18.3 1.6 0.0087 15.4 0.1 2.8 2 0 0 2 2 2 1 N-terminal domain of cytochrome oxidase-cbb3, FixP MFS_1 PF07690.11 EIW74736.1 - 4.2e-28 98.0 26.8 6.5e-28 97.4 18.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily NfeD PF01957.13 EIW74736.1 - 4.8 7.3 0.0 4.8 7.3 0.0 3.6 2 2 1 3 3 3 0 NfeD-like C-terminal, partner-binding MFS_1 PF07690.11 EIW74737.1 - 1.8e-29 102.6 28.0 1.8e-29 102.6 19.4 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3993 PF13158.1 EIW74737.1 - 0.046 13.5 0.3 0.15 11.8 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3993) DUF4538 PF15061.1 EIW74737.1 - 0.81 9.0 4.5 5.8 6.3 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4538) Serglycin PF04360.7 EIW74738.1 - 0.17 11.6 1.7 0.3 10.8 1.2 1.4 1 0 0 1 1 1 0 Serglycin Lig_chan PF00060.21 EIW74738.1 - 1.9 8.2 5.6 0.37 10.5 1.4 1.6 2 0 0 2 2 2 0 Ligand-gated ion channel Abhydrolase_6 PF12697.2 EIW74739.1 - 2.2e-24 86.6 0.2 2.8e-24 86.2 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW74739.1 - 2.3e-09 37.1 0.7 4.7e-09 36.1 0.5 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW74739.1 - 7.2e-09 35.5 0.4 6.5e-06 25.8 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EIW74739.1 - 3.5e-06 26.7 0.3 1.5e-05 24.7 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase PMSR PF01625.16 EIW74745.1 - 5e-46 156.4 0.0 6.6e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase OPT PF03169.10 EIW74746.1 - 9.3e-96 321.6 42.4 1.1e-95 321.4 29.4 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4191 PF13829.1 EIW74746.1 - 2.8 6.9 5.0 3.9 6.5 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) UCR_hinge PF02320.11 EIW74747.1 - 3e-23 81.5 4.2 5.3e-23 80.7 2.9 1.4 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein Sigma70_ner PF04546.8 EIW74747.1 - 0.001 18.7 4.6 0.0013 18.4 3.2 1.1 1 0 0 1 1 1 1 Sigma-70, non-essential region CobT PF06213.7 EIW74747.1 - 0.071 12.2 8.3 0.09 11.8 5.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT YqfQ PF14181.1 EIW74747.1 - 0.16 12.0 2.7 0.16 11.9 1.9 1.2 1 0 0 1 1 1 0 YqfQ-like protein TRAP_alpha PF03896.11 EIW74747.1 - 0.22 10.4 5.1 0.25 10.2 3.5 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit C8 PF08742.6 EIW74747.1 - 0.23 11.7 3.7 0.34 11.2 2.6 1.3 1 0 0 1 1 1 0 C8 domain DUF1510 PF07423.6 EIW74747.1 - 0.48 9.7 8.6 0.5 9.7 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Daxx PF03344.10 EIW74747.1 - 0.61 8.5 10.1 0.6 8.5 7.0 1.0 1 0 0 1 1 1 0 Daxx Family CENP-B_dimeris PF09026.5 EIW74747.1 - 0.67 10.2 8.7 0.82 9.9 6.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.9 EIW74747.1 - 0.77 7.7 2.6 0.78 7.7 1.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4349 PF14257.1 EIW74747.1 - 1 8.5 3.5 1.2 8.3 2.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) DUF3408 PF11888.3 EIW74747.1 - 1.5 8.7 9.4 22 4.9 4.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Paf1 PF03985.8 EIW74747.1 - 1.8 7.1 7.2 2.1 6.9 5.0 1.1 1 0 0 1 1 1 0 Paf1 Tim54 PF11711.3 EIW74747.1 - 2.4 6.6 5.7 2.5 6.6 4.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 HSP90 PF00183.13 EIW74747.1 - 2.9 6.1 7.2 3.1 6.0 5.0 1.1 1 0 0 1 1 1 0 Hsp90 protein DUF3530 PF12048.3 EIW74747.1 - 3.3 6.6 5.4 3.7 6.4 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) CT47 PF15623.1 EIW74747.1 - 3.7 7.1 17.0 4.3 7.0 11.8 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 VID27 PF08553.5 EIW74747.1 - 4.8 5.2 6.4 5.1 5.1 4.4 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein Herpes_DNAp_acc PF04929.7 EIW74747.1 - 8.3 5.2 6.7 10 4.9 4.6 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor WD40 PF00400.27 EIW74748.1 - 2e-147 474.4 33.9 1.4e-12 46.9 0.3 14.2 14 0 0 14 14 14 14 WD domain, G-beta repeat eIF2A PF08662.6 EIW74748.1 - 5.2e-18 65.4 0.0 0.0046 16.6 0.0 6.9 3 2 3 7 7 7 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EIW74748.1 - 2e-11 43.2 8.6 2.3 7.9 0.0 11.0 12 0 0 12 12 12 1 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EIW74748.1 - 6.3e-09 34.5 9.0 0.8 7.7 0.0 8.2 5 3 2 7 7 7 3 Nucleoporin Nup120/160 Nbas_N PF15492.1 EIW74748.1 - 8.6e-07 28.3 2.3 0.63 9.0 0.0 7.7 3 3 4 9 9 9 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 EIW74748.1 - 1.9e-06 26.8 0.2 0.2 10.3 0.0 5.8 3 2 2 6 6 6 2 Nup133 N terminal like TFIIIC_delta PF12657.2 EIW74748.1 - 9.6e-06 25.4 3.2 1 9.0 0.0 5.3 5 2 0 5 5 5 1 Transcription factor IIIC subunit delta N-term Proteasome_A_N PF10584.4 EIW74748.1 - 6.7e-05 22.1 1.3 1.4e+02 1.9 0.0 8.2 9 0 0 9 9 9 0 Proteasome subunit A N-terminal signature PQQ_2 PF13360.1 EIW74748.1 - 0.00011 21.7 4.0 0.068 12.6 0.1 4.8 3 2 2 6 6 6 1 PQQ-like domain IKI3 PF04762.7 EIW74748.1 - 0.0014 16.5 1.6 0.058 11.2 0.0 3.9 4 1 1 5 5 5 1 IKI3 family Peptidase_S9_N PF02897.10 EIW74748.1 - 0.0048 15.5 1.2 13 4.1 0.0 4.5 2 1 3 5 5 5 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Apc4_WD40 PF12894.2 EIW74748.1 - 0.0054 16.2 0.0 0.66 9.5 0.0 4.2 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.1 EIW74748.1 - 0.039 14.2 10.0 55 4.2 0.0 7.3 7 1 2 9 9 9 0 PQQ-like domain Coatomer_WDAD PF04053.9 EIW74748.1 - 0.045 12.5 0.1 0.6 8.8 0.0 2.8 3 1 0 3 3 3 0 Coatomer WD associated region Sod_Fe_C PF02777.13 EIW74749.1 - 1.3e-38 131.1 0.2 2.4e-38 130.2 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EIW74749.1 - 5.3e-32 109.9 4.3 5.3e-32 109.9 3.0 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain ATP-synt_DE PF00401.15 EIW74749.1 - 1.4 8.8 4.2 3.1 7.7 0.8 2.2 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain adh_short PF00106.20 EIW74750.1 - 4.4e-26 91.7 0.1 5.7e-26 91.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW74750.1 - 1e-22 81.0 0.0 1.3e-22 80.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW74750.1 - 2.2e-14 53.5 0.0 3.1e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EIW74750.1 - 0.019 13.6 0.0 0.027 13.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family BNIP2 PF12496.3 EIW74750.1 - 0.032 14.3 0.1 0.051 13.7 0.0 1.3 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 adh_short PF00106.20 EIW74751.1 - 2.6e-20 72.9 0.0 3.5e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW74751.1 - 8.3e-19 68.2 0.0 1.1e-18 67.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW74751.1 - 9.3e-08 31.9 0.0 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EIW74751.1 - 0.094 11.4 0.0 0.31 9.7 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PseudoU_synth_2 PF00849.17 EIW74752.1 - 8.1e-29 100.5 0.0 1.1e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase DUF1800 PF08811.6 EIW74752.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) HEV_ORF1 PF02444.11 EIW74753.1 - 0.6 10.3 4.6 9.1 6.5 0.5 2.7 1 1 2 3 3 3 0 Hepatitis E virus ORF-2 (Putative capsid protein) FAD_binding_4 PF01565.18 EIW74754.1 - 0.054 12.9 0.0 0.079 12.4 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain ARL6IP6 PF15062.1 EIW74754.1 - 1.7 8.6 5.9 0.88 9.5 1.0 2.5 1 1 2 3 3 3 0 Haemopoietic lineage transmembrane helix Glyco_hydro_3 PF00933.16 EIW74755.1 - 2.4e-75 253.3 0.1 3.4e-75 252.8 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIW74755.1 - 2.8e-57 193.8 0.2 2.8e-57 193.8 0.1 2.5 3 0 0 3 3 3 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIW74755.1 - 5.6e-17 61.4 0.1 1.1e-16 60.4 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Transposase_21 PF02992.9 EIW74757.1 - 0.1 11.6 0.0 0.25 10.4 0.0 1.6 1 0 0 1 1 1 0 Transposase family tnp2 adh_short PF00106.20 EIW74759.1 - 1e-21 77.5 0.1 1.5e-21 77.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW74759.1 - 4e-08 33.1 0.1 6.3e-08 32.4 0.1 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EIW74759.1 - 0.00017 21.6 0.1 0.00035 20.6 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EIW74759.1 - 0.0002 20.9 0.1 0.00058 19.3 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW74759.1 - 0.00021 21.3 0.2 0.00049 20.1 0.1 1.6 2 0 0 2 2 2 1 NADH(P)-binding adh_short_C2 PF13561.1 EIW74759.1 - 0.00026 20.8 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase QRPTase_C PF01729.14 EIW74759.1 - 0.017 14.6 0.1 0.029 13.9 0.1 1.3 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain NmrA PF05368.8 EIW74759.1 - 0.023 13.9 0.1 0.041 13.1 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family THF_DHG_CYH_C PF02882.14 EIW74759.1 - 0.051 12.6 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.10 EIW74759.1 - 0.053 12.4 0.0 0.073 11.9 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.1 EIW74759.1 - 0.12 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding adh_short PF00106.20 EIW74760.1 - 7.3e-20 71.5 2.5 7.3e-20 71.5 1.7 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW74760.1 - 3e-11 43.5 3.2 5.3e-11 42.7 2.2 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW74760.1 - 5.8e-09 35.8 2.5 1.5e-08 34.5 1.7 1.6 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIW74760.1 - 4.2e-06 26.8 0.8 5.5e-05 23.2 0.1 2.5 3 0 0 3 3 3 1 NADH(P)-binding Epimerase PF01370.16 EIW74760.1 - 9.7e-06 25.1 0.4 2.3e-05 23.9 0.1 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EIW74760.1 - 0.034 13.9 1.5 0.1 12.4 0.1 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EIW74760.1 - 0.087 11.9 0.0 0.27 10.3 0.0 1.6 1 1 1 2 2 2 0 Fungal family of unknown function (DUF1776) SNF2_N PF00176.18 EIW74761.1 - 8.5e-68 228.3 0.0 1.2e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW74761.1 - 2.3e-13 49.8 0.0 7.3e-13 48.1 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 EIW74761.1 - 1.7e-05 24.5 3.0 3.6e-05 23.5 2.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIW74761.1 - 4.8e-05 22.9 1.8 4.8e-05 22.9 1.2 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIW74761.1 - 0.00017 21.2 2.0 0.00051 19.6 1.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EIW74761.1 - 0.00046 19.8 5.1 0.0011 18.5 3.5 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIW74761.1 - 0.0042 16.7 7.7 0.012 15.2 5.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW74761.1 - 0.0077 16.2 5.4 0.022 14.7 3.7 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIW74761.1 - 0.013 15.3 2.8 0.034 14.0 1.9 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PAP2 PF01569.16 EIW74763.1 - 1.6e-26 92.5 2.5 1.6e-26 92.5 1.7 2.0 2 0 0 2 2 2 1 PAP2 superfamily PEMT PF04191.8 EIW74764.1 - 7.5e-30 103.1 1.2 7.5e-30 103.1 0.8 1.6 2 0 0 2 2 2 1 Phospholipid methyltransferase zf-H2C2 PF09337.5 EIW74765.1 - 0.00072 18.9 0.6 0.0012 18.1 0.4 1.4 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger KA1 PF02149.14 EIW74766.1 - 0.025 13.9 0.0 0.051 13.0 0.0 1.5 1 0 0 1 1 1 0 Kinase associated domain 1 Pkinase PF00069.20 EIW74767.1 - 9.9e-65 218.2 0.0 1.1e-64 218.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW74767.1 - 3.9e-38 130.9 0.0 5.1e-38 130.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW74767.1 - 9.1e-07 28.1 0.0 1.3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EIW74767.1 - 0.0004 19.7 0.2 0.0006 19.2 0.1 1.2 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EIW74767.1 - 0.0055 16.4 0.4 0.017 14.9 0.2 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Phage_T7_Capsid PF05396.6 EIW74767.1 - 0.055 13.6 0.0 0.093 12.8 0.0 1.3 1 0 0 1 1 1 0 Phage T7 capsid assembly protein YrbL-PhoP_reg PF10707.4 EIW74767.1 - 0.068 12.5 0.3 0.12 11.7 0.0 1.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Lyase_1 PF00206.15 EIW74768.1 - 2.4e-22 79.5 0.0 3.3e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EIW74768.1 - 3.3e-16 59.0 0.0 7.9e-16 57.8 0.0 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus MSSP PF03940.8 EIW74769.1 - 0.035 13.4 1.1 0.056 12.8 0.8 1.4 1 0 0 1 1 1 0 Male specific sperm protein SNARE_assoc PF09335.6 EIW74770.1 - 3.3e-14 53.1 5.1 5.6e-14 52.4 2.9 1.9 1 1 0 1 1 1 1 SNARE associated Golgi protein HAMP PF00672.20 EIW74770.1 - 0.34 11.1 2.4 16 5.7 0.8 2.9 2 0 0 2 2 2 0 HAMP domain P16-Arc PF04699.9 EIW74771.1 - 6e-53 178.9 0.0 6.6e-53 178.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF2711 PF10924.3 EIW74771.1 - 0.07 12.5 0.0 0.092 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) P16-Arc PF04699.9 EIW74773.1 - 1e-16 61.3 0.0 1.2e-16 61.0 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) MHYT PF03707.11 EIW74774.1 - 0.15 12.2 2.4 2 8.5 0.9 2.6 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat UIM PF02809.15 EIW74775.1 - 0.088 12.4 0.3 0.088 12.4 0.2 2.9 3 0 0 3 3 3 0 Ubiquitin interaction motif WD40 PF00400.27 EIW74775.1 - 3 7.8 5.6 0.59 10.1 0.4 2.4 2 0 0 2 2 2 0 WD domain, G-beta repeat SNase PF00565.12 EIW74776.1 - 6.6e-19 68.1 0.0 9.9e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Selenoprotein_S PF06936.6 EIW74776.1 - 0.0058 16.1 4.7 0.0086 15.6 3.2 1.2 1 0 0 1 1 1 1 Selenoprotein S (SelS) DUF3736 PF12540.3 EIW74776.1 - 0.11 12.7 2.6 0.22 11.7 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3736) PLA2_B PF01735.13 EIW74777.1 - 3e-98 329.1 0.0 4.3e-98 328.6 0.0 1.2 1 0 0 1 1 1 1 Lysophospholipase catalytic domain NmrA PF05368.8 EIW74779.1 - 5.2e-18 65.1 0.0 6.8e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIW74779.1 - 1.2e-05 25.4 0.4 1.4e-05 25.1 0.3 1.3 1 0 0 1 1 1 1 NADH(P)-binding CPSase_L_chain PF00289.17 EIW74779.1 - 5.5e-05 23.2 0.0 9.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Epimerase PF01370.16 EIW74779.1 - 0.0096 15.3 0.1 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EIW74779.1 - 0.028 14.0 0.1 0.043 13.4 0.1 1.4 1 0 0 1 1 1 0 KR domain Glyco_hydro_3 PF00933.16 EIW74780.1 - 6.7e-78 261.6 0.1 9.5e-78 261.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIW74780.1 - 1.9e-56 191.0 0.4 7.3e-56 189.2 0.3 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIW74780.1 - 3.1e-17 62.2 0.0 5.8e-17 61.3 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF4243 PF14027.1 EIW74781.1 - 1.2e-72 245.1 0.0 1.7e-72 244.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF4243 PF14027.1 EIW74782.1 - 7.7e-09 35.4 0.0 1.1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF3446 PF11928.3 EIW74782.1 - 0.3 11.3 3.9 0.91 9.7 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Peptidase_M50B PF13398.1 EIW74786.1 - 0.05 12.9 1.1 0.16 11.3 0.8 1.6 1 1 0 1 1 1 0 Peptidase M50B-like N-glycanase_N PF09112.5 EIW74786.1 - 0.059 12.7 0.0 0.076 12.3 0.0 1.2 1 0 0 1 1 1 0 Peptide-N-glycosidase F, N terminal 7TMR-DISM_7TM PF07695.6 EIW74786.1 - 0.072 12.7 0.9 0.087 12.4 0.6 1.1 1 0 0 1 1 1 0 7TM diverse intracellular signalling BAR PF03114.13 EIW74787.1 - 4.1e-39 134.4 13.2 5.3e-39 134.0 9.1 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 EIW74787.1 - 1.4e-14 53.4 0.1 3.3e-14 52.1 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIW74787.1 - 4.2e-12 45.2 0.0 1.1e-11 43.9 0.0 1.8 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIW74787.1 - 8.8e-11 41.1 0.0 2.5e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain HlyD PF00529.15 EIW74787.1 - 0.12 11.6 4.4 0.22 10.7 3.0 1.4 1 0 0 1 1 1 0 HlyD family secretion protein V_ATPase_I PF01496.14 EIW74787.1 - 0.47 8.2 8.0 0.63 7.8 5.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 EIW74787.1 - 3.2 6.0 6.4 4.8 5.4 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) APG6 PF04111.7 EIW74787.1 - 5.2 6.0 13.2 9.6 5.1 9.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 MscS_TM PF12794.2 EIW74787.1 - 9.3 4.7 7.1 14 4.1 4.9 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 SWIB PF02201.13 EIW74788.1 - 1.9e-16 59.4 0.0 4.7e-16 58.2 0.0 1.7 1 0 0 1 1 1 1 SWIB/MDM2 domain FAD_binding_1 PF00667.15 EIW74789.1 - 8.3e-39 133.2 0.0 1.3e-38 132.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EIW74789.1 - 4.1e-30 104.6 0.0 2.2e-29 102.2 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EIW74789.1 - 1.7e-09 38.2 0.0 3.1e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EIW74789.1 - 0.0094 15.9 0.0 0.041 13.8 0.0 2.0 1 1 1 2 2 2 1 Flavodoxin domain FAD_binding_6 PF00970.19 EIW74789.1 - 0.016 15.2 0.0 0.071 13.2 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain SBP_bac_5 PF00496.17 EIW74789.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle DUF2491 PF10679.4 EIW74790.1 - 0.15 11.0 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) DUF1373 PF07117.6 EIW74791.1 - 0.043 13.5 0.0 0.059 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) Nop10p PF04135.7 EIW74791.1 - 0.11 12.2 0.2 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Nucleolar RNA-binding protein, Nop10p family DUF2076 PF09849.4 EIW74793.1 - 0.22 11.5 1.2 0.38 10.7 0.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Bradykinin PF06753.7 EIW74794.1 - 0.46 10.0 0.2 0.46 10.0 0.2 1.9 3 0 0 3 3 3 0 Bradykinin Cellulase PF00150.13 EIW74795.1 - 1.9e-44 151.9 0.0 2.4e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.1 EIW74795.1 - 0.068 12.4 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) TFIIIC_delta PF12657.2 EIW74796.1 - 1.5e-26 93.1 2.2 4.4e-26 91.6 1.1 2.0 1 1 0 1 1 1 1 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 EIW74796.1 - 1.2e-21 76.4 1.4 2.8e-21 75.2 0.9 1.7 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex GST_N_3 PF13417.1 EIW74797.1 - 4.2e-12 46.1 0.1 7.1e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW74797.1 - 1.6e-07 31.1 0.0 3.3e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW74797.1 - 2.7e-06 27.2 0.0 4.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW74797.1 - 0.0012 18.7 0.0 0.0041 17.0 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW74797.1 - 0.0025 17.9 0.0 0.007 16.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIW74797.1 - 0.017 15.5 0.0 0.026 15.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Sugar_tr PF00083.19 EIW74799.1 - 1.1e-96 324.2 21.0 1.2e-96 324.0 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW74799.1 - 6.1e-27 94.2 60.0 3.6e-23 81.8 18.7 2.4 1 1 2 3 3 3 2 Major Facilitator Superfamily OATP PF03137.15 EIW74799.1 - 9.5e-05 20.6 0.7 0.0002 19.5 0.5 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.19 EIW74800.1 - 1.6e-97 326.9 22.2 1.8e-97 326.7 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW74800.1 - 6.8e-23 80.9 43.5 1.5e-14 53.5 6.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EIW74800.1 - 7.9e-06 24.2 1.4 1.7e-05 23.1 1.0 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family GST_N_3 PF13417.1 EIW74801.1 - 4.5e-10 39.6 0.1 8e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW74801.1 - 2.1e-06 27.5 0.1 3.6e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW74801.1 - 5.1e-06 26.3 0.0 8.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW74801.1 - 0.00089 19.2 0.0 0.002 18.0 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW74801.1 - 0.011 15.8 0.1 0.029 14.5 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIW74801.1 - 0.12 12.8 0.0 0.2 12.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain FMN_bind_2 PF04299.7 EIW74802.1 - 2.2e-48 163.9 0.0 2.6e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain adh_short PF00106.20 EIW74803.1 - 2.5e-24 86.0 0.0 4.6e-24 85.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW74803.1 - 1.7e-15 57.4 0.0 2.2e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW74803.1 - 3.5e-10 39.8 0.0 8e-10 38.6 0.0 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW74803.1 - 4.4e-06 26.3 0.1 2.5e-05 23.8 0.0 2.2 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW74803.1 - 1.1e-05 25.5 0.0 2.8e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EIW74803.1 - 0.017 14.8 0.2 0.1 12.4 0.0 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EIW74803.1 - 0.037 13.1 0.0 0.052 12.6 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF2717 PF10911.3 EIW74803.1 - 0.11 12.0 0.0 0.64 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2717) UQ_con PF00179.21 EIW74804.1 - 1e-49 167.5 0.0 1.2e-49 167.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIW74804.1 - 1e-07 31.7 0.0 1.9e-07 30.9 0.0 1.5 1 1 1 2 2 2 1 Prokaryotic E2 family B Glyco_hydro_3 PF00933.16 EIW74805.1 - 1.5e-84 283.5 0.1 2.1e-84 283.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIW74805.1 - 1.3e-59 201.4 2.7 3e-59 200.3 1.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIW74805.1 - 1.2e-17 63.5 0.1 2.7e-17 62.4 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain ABC1 PF03109.11 EIW74807.1 - 8.4e-25 87.0 0.0 1.6e-24 86.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family UQ_con PF00179.21 EIW74809.1 - 1.7e-37 127.9 0.0 2.2e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RRM_1 PF00076.17 EIW74810.1 - 7.7e-23 79.9 0.3 3.6e-12 45.7 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW74810.1 - 2.6e-18 65.7 0.2 2.5e-10 40.1 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW74810.1 - 6.3e-08 32.3 0.0 0.004 16.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ICMT PF04140.9 EIW74812.1 - 2e-14 53.5 2.0 1.3e-12 47.7 0.2 2.4 1 1 1 2 2 2 2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIW74812.1 - 3.6e-11 43.0 2.5 1.1e-10 41.4 1.0 2.1 1 1 1 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 EIW74812.1 - 0.00066 19.0 0.2 0.001 18.4 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 EIW74812.1 - 0.014 13.9 0.4 0.042 12.3 0.5 1.6 2 0 0 2 2 2 0 Ergosterol biosynthesis ERG4/ERG24 family PQQ_2 PF13360.1 EIW74814.1 - 0.0052 16.2 0.2 16 4.8 0.0 3.7 3 1 0 3 3 3 2 PQQ-like domain WD40 PF00400.27 EIW74814.1 - 0.031 14.1 3.1 1.4 8.8 0.1 4.4 3 0 0 3 3 3 0 WD domain, G-beta repeat Gag_p19 PF02228.11 EIW74814.1 - 0.11 12.8 0.1 0.28 11.5 0.0 1.7 1 0 0 1 1 1 0 Major core protein p19 NACHT PF05729.7 EIW74815.1 - 6.2e-09 35.7 0.0 7.4e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW74815.1 - 2.3e-07 30.9 0.0 2.5e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW74815.1 - 2.7e-06 27.5 0.0 3.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EIW74815.1 - 8.5e-05 21.6 0.0 8.5e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 EIW74815.1 - 0.00012 21.8 0.0 0.00013 21.7 0.0 1.2 1 1 0 1 1 1 1 NTPase APS_kinase PF01583.15 EIW74815.1 - 0.00014 21.6 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.17 EIW74815.1 - 0.00021 21.4 0.0 0.00035 20.7 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 EIW74815.1 - 0.00026 21.3 0.0 0.00031 21.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW74815.1 - 0.00026 20.6 0.0 0.00043 19.9 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EIW74815.1 - 0.00034 20.5 0.0 0.0004 20.2 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW74815.1 - 0.00071 20.3 0.0 0.001 19.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIW74815.1 - 0.0016 17.5 0.0 0.0025 16.9 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin KTI12 PF08433.5 EIW74815.1 - 0.0017 17.5 0.0 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_29 PF13555.1 EIW74815.1 - 0.0038 16.7 0.0 0.0093 15.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ArgK PF03308.11 EIW74815.1 - 0.0038 16.0 0.0 0.0052 15.5 0.0 1.2 1 0 0 1 1 1 1 ArgK protein ABC_tran PF00005.22 EIW74815.1 - 0.0049 17.1 0.0 0.0053 17.0 0.0 1.2 1 0 0 1 1 1 1 ABC transporter KaiC PF06745.8 EIW74815.1 - 0.0067 15.5 0.0 0.012 14.6 0.0 1.4 2 0 0 2 2 2 1 KaiC Arch_ATPase PF01637.13 EIW74815.1 - 0.0084 15.8 0.0 0.0084 15.8 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase AAA PF00004.24 EIW74815.1 - 0.017 15.3 0.0 0.025 14.7 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PRK PF00485.13 EIW74815.1 - 0.018 14.6 0.0 0.02 14.4 0.0 1.3 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family T2SE PF00437.15 EIW74815.1 - 0.02 13.7 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein RuvB_N PF05496.7 EIW74815.1 - 0.04 12.9 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NB-ARC PF00931.17 EIW74815.1 - 0.041 12.7 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activ_2 PF14532.1 EIW74815.1 - 0.045 13.8 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 EIW74815.1 - 0.057 12.8 0.0 0.086 12.3 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_5 PF07728.9 EIW74815.1 - 0.062 13.0 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.10 EIW74815.1 - 0.065 11.9 0.0 0.074 11.7 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein CoaE PF01121.15 EIW74815.1 - 0.07 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase Viral_helicase1 PF01443.13 EIW74815.1 - 0.075 12.5 0.0 0.083 12.3 0.0 1.1 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 EIW74815.1 - 0.086 12.2 0.0 0.11 11.9 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 EIW74815.1 - 0.098 12.5 0.0 0.12 12.2 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EIW74815.1 - 0.11 11.8 0.0 0.26 10.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_31 PF13614.1 EIW74815.1 - 0.14 12.1 0.0 0.14 12.0 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EIW74815.1 - 0.15 11.6 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EIW74816.1 - 2.9e-08 33.5 0.0 4.6e-08 32.8 0.0 1.3 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW74816.1 - 2e-07 31.1 0.0 2.2e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.15 EIW74816.1 - 4.9e-05 23.0 0.0 5.4e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.1 EIW74816.1 - 0.00012 22.1 0.0 0.00016 21.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EIW74816.1 - 0.0002 20.9 0.0 0.00027 20.5 0.0 1.4 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_33 PF13671.1 EIW74816.1 - 0.00026 20.8 0.0 0.0012 18.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EIW74816.1 - 0.00044 20.3 0.0 0.00069 19.7 0.0 1.3 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.10 EIW74816.1 - 0.00055 19.6 0.0 0.0007 19.3 0.0 1.3 1 0 0 1 1 1 1 NTPase AAA_18 PF13238.1 EIW74816.1 - 0.0037 17.5 0.0 0.004 17.4 0.0 1.2 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIW74816.1 - 0.0052 17.0 0.0 0.0052 17.0 0.0 1.3 1 1 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.7 EIW74816.1 - 0.0054 15.8 0.0 0.008 15.2 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin DEAD PF00270.24 EIW74816.1 - 0.0082 15.6 0.0 0.01 15.3 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase MobB PF03205.9 EIW74816.1 - 0.0088 15.7 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EIW74816.1 - 0.01 16.6 0.2 0.02 15.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EIW74816.1 - 0.014 15.0 0.0 0.017 14.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 CbiA PF01656.18 EIW74816.1 - 0.018 14.4 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.24 EIW74816.1 - 0.03 14.5 0.0 0.03 14.5 0.0 1.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EIW74816.1 - 0.031 13.2 0.0 0.032 13.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 EIW74816.1 - 0.032 13.9 0.0 0.048 13.3 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase AAA_19 PF13245.1 EIW74816.1 - 0.034 13.8 0.0 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain TIP49 PF06068.8 EIW74816.1 - 0.039 12.6 0.0 0.046 12.4 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus Gp37_Gp68 PF07505.6 EIW74816.1 - 0.043 12.9 0.0 0.043 12.9 0.0 1.1 1 0 0 1 1 1 0 Phage protein Gp37/Gp68 SRP54 PF00448.17 EIW74816.1 - 0.066 12.6 0.0 0.14 11.6 0.0 1.5 1 1 1 2 2 2 0 SRP54-type protein, GTPase domain PhoH PF02562.11 EIW74816.1 - 0.071 12.3 0.1 0.071 12.3 0.0 1.2 1 1 0 1 1 1 0 PhoH-like protein KaiC PF06745.8 EIW74816.1 - 0.077 12.0 0.1 0.11 11.6 0.1 1.2 1 0 0 1 1 1 0 KaiC FtsK_SpoIIIE PF01580.13 EIW74816.1 - 0.081 12.3 0.1 0.41 10.0 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 EIW74816.1 - 0.088 11.4 0.2 0.14 10.7 0.1 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_29 PF13555.1 EIW74816.1 - 0.099 12.1 0.4 0.22 11.0 0.1 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Thymidylate_kin PF02223.12 EIW74816.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase RuvB_N PF05496.7 EIW74816.1 - 0.13 11.3 0.0 0.43 9.5 0.0 1.7 1 1 1 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus T2SE PF00437.15 EIW74816.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 EIW74816.1 - 0.14 12.0 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Rtt106 PF08512.7 EIW74817.1 - 6.6e-16 58.0 0.0 1.2e-15 57.2 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Nop14 PF04147.7 EIW74817.1 - 0.094 10.6 11.5 0.13 10.1 8.0 1.3 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EIW74817.1 - 4.4 5.6 12.4 10 4.4 8.6 1.6 1 0 0 1 1 1 0 Daxx Family Prefoldin PF02996.12 EIW74820.1 - 7e-26 90.2 0.9 7.8e-24 83.6 0.6 2.4 2 1 0 2 2 2 1 Prefoldin subunit UPF0139 PF03669.8 EIW74820.1 - 0.02 14.4 0.0 2 7.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) Syntaxin-6_N PF09177.6 EIW74820.1 - 0.26 11.7 6.1 3.8 7.9 1.2 2.8 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Lebercilin PF15619.1 EIW74820.1 - 0.6 9.4 4.9 5.6 6.3 0.9 2.4 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease S-antigen PF05756.6 EIW74820.1 - 7.2 6.6 8.0 2e+02 2.0 5.5 2.2 1 1 0 1 1 1 0 S-antigen protein RRM_1 PF00076.17 EIW74821.1 - 1.2e-68 226.7 0.0 1.9e-18 65.8 0.0 5.9 5 1 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW74821.1 - 1.9e-59 197.5 0.0 4.4e-16 58.6 0.0 5.7 6 0 0 6 6 6 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW74821.1 - 3.1e-29 100.5 0.0 6.3e-10 38.7 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIW74821.1 - 1.5e-05 24.6 0.0 0.043 13.5 0.0 4.3 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif adh_short PF00106.20 EIW74822.1 - 7e-26 91.1 0.0 1.3e-25 90.3 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW74822.1 - 6.8e-14 52.2 0.0 9e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW74822.1 - 5.3e-11 42.5 0.0 1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW74822.1 - 0.00017 21.0 0.0 0.00026 20.5 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW74822.1 - 0.0025 17.8 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EIW74822.1 - 0.076 11.8 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 EIW74822.1 - 0.094 12.5 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.20 EIW74823.1 - 6.3e-26 91.2 0.0 8.2e-26 90.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW74823.1 - 1.9e-11 44.2 0.0 2.5e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW74823.1 - 1.1e-10 41.5 0.0 2.2e-10 40.5 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW74823.1 - 0.00026 20.5 0.0 0.00062 19.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW74823.1 - 0.017 15.0 0.1 0.027 14.4 0.0 1.4 1 1 0 1 1 1 0 NADH(P)-binding RmlD_sub_bind PF04321.12 EIW74823.1 - 0.063 12.1 0.0 0.094 11.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 EIW74823.1 - 0.084 12.6 0.1 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Mito_carr PF00153.22 EIW74824.1 - 1.9e-64 213.4 2.5 3.4e-22 77.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein SRP9-21 PF05486.7 EIW74825.1 - 2.7e-19 68.6 0.9 3.5e-19 68.3 0.6 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) EAP30 PF04157.11 EIW74826.1 - 1.6e-38 132.0 0.0 1.2e-37 129.2 0.0 2.0 1 1 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EIW74826.1 - 2.7e-18 65.5 0.0 4.8e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 DZR PF12773.2 EIW74826.1 - 3.9e-05 23.3 3.7 7.7e-05 22.4 2.6 1.5 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 EIW74826.1 - 9.7e-05 21.4 8.5 0.0043 16.2 0.4 2.4 2 0 0 2 2 2 2 zinc-ribbon domain zf-RanBP PF00641.13 EIW74826.1 - 0.0005 19.1 11.0 0.0011 17.9 0.4 2.5 2 1 0 2 2 2 2 Zn-finger in Ran binding protein and others DUF4285 PF14113.1 EIW74826.1 - 0.13 12.2 0.0 0.34 10.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4285) zf-Sec23_Sec24 PF04810.10 EIW74826.1 - 0.33 10.5 8.9 1 8.9 0.4 3.1 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger STE PF02200.11 EIW74827.1 - 9.7e-54 180.2 0.0 1.3e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 STE like transcription factor DUF1687 PF07955.6 EIW74828.1 - 0.00011 22.2 0.0 0.00043 20.2 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) Tyrosinase PF00264.15 EIW74829.1 - 6.5e-44 150.7 1.1 1.1e-43 149.9 0.8 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase LRR_4 PF12799.2 EIW74832.1 - 0.016 14.7 1.5 1.6 8.4 0.0 4.1 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_4 PF12799.2 EIW74833.1 - 0.0068 16.0 0.1 1.2 8.8 0.0 3.6 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) Phosphorylase PF00343.15 EIW74834.1 - 1.7e-297 988.1 0.0 2e-297 987.9 0.0 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase NACHT PF05729.7 EIW74835.1 - 4.2e-08 33.0 0.0 6.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW74835.1 - 6e-07 29.6 0.1 7.6e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 EIW74835.1 - 0.00018 20.4 0.0 0.00022 20.2 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain Zeta_toxin PF06414.7 EIW74835.1 - 0.0004 19.5 0.0 0.0007 18.7 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 EIW74835.1 - 0.00065 19.8 0.0 0.00093 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EIW74835.1 - 0.0012 18.5 0.1 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase Arch_ATPase PF01637.13 EIW74835.1 - 0.0034 17.1 0.0 0.0038 16.9 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase NTPase_1 PF03266.10 EIW74835.1 - 0.0061 16.2 0.0 0.0083 15.8 0.0 1.3 1 1 0 1 1 1 1 NTPase UPF0079 PF02367.12 EIW74835.1 - 0.0064 16.1 0.0 0.0089 15.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EIW74835.1 - 0.0086 16.2 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA helicase PhoH PF02562.11 EIW74835.1 - 0.0098 15.1 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein PRK PF00485.13 EIW74835.1 - 0.021 14.3 0.0 0.055 13.0 0.0 1.8 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family KaiC PF06745.8 EIW74835.1 - 0.021 13.9 0.0 0.032 13.3 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.1 EIW74835.1 - 0.021 14.5 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain ABC_tran PF00005.22 EIW74835.1 - 0.028 14.7 0.0 0.031 14.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 EIW74835.1 - 0.029 14.2 0.3 0.084 12.7 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EIW74835.1 - 0.045 14.0 0.0 0.062 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EIW74835.1 - 0.054 13.6 0.0 0.081 13.1 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EIW74835.1 - 0.061 12.2 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein RuvB_N PF05496.7 EIW74835.1 - 0.065 12.2 0.0 0.12 11.3 0.0 1.4 1 1 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF2075 PF09848.4 EIW74835.1 - 0.094 11.6 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.12 EIW74835.1 - 0.11 11.2 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_29 PF13555.1 EIW74835.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_30 PF13604.1 EIW74835.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EIW74835.1 - 0.16 10.6 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus PigN PF04987.9 EIW74837.1 - 2e-106 356.3 6.1 3.1e-106 355.6 4.2 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EIW74837.1 - 5.7e-11 42.3 1.4 4.9e-09 35.9 0.6 2.7 1 1 2 3 3 3 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EIW74837.1 - 1.2e-05 24.6 0.1 1.8e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EIW74837.1 - 0.007 15.7 0.1 0.014 14.7 0.1 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily F-box-like PF12937.2 EIW74838.1 - 7.2e-07 28.8 1.6 3.7e-06 26.5 1.1 2.2 1 1 0 1 1 1 1 F-box-like Actino_peptide PF14408.1 EIW74838.1 - 0.026 14.4 0.2 0.047 13.6 0.2 1.4 1 0 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes AAA_16 PF13191.1 EIW74839.1 - 3e-08 33.8 0.1 3.6e-08 33.5 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EIW74839.1 - 3.5e-07 30.0 0.0 4.2e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EIW74839.1 - 3e-05 24.1 0.0 3.9e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EIW74839.1 - 0.0001 22.0 0.0 0.00013 21.8 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase ABC_tran PF00005.22 EIW74839.1 - 0.00011 22.5 0.0 0.00012 22.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter RNA_helicase PF00910.17 EIW74839.1 - 0.00018 21.6 0.0 0.00034 20.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_29 PF13555.1 EIW74839.1 - 0.00061 19.2 0.1 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain APS_kinase PF01583.15 EIW74839.1 - 0.00063 19.4 0.1 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase NTPase_1 PF03266.10 EIW74839.1 - 0.00072 19.2 0.0 0.0015 18.2 0.0 1.4 1 1 0 1 1 1 1 NTPase T2SE PF00437.15 EIW74839.1 - 0.00088 18.2 0.0 0.0012 17.8 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF258 PF03193.11 EIW74839.1 - 0.0014 17.7 0.0 0.0015 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PIF1 PF05970.9 EIW74839.1 - 0.0016 17.4 0.0 0.0021 17.0 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_18 PF13238.1 EIW74839.1 - 0.0017 18.6 0.0 0.002 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EIW74839.1 - 0.0035 16.8 0.0 0.0046 16.4 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF2075 PF09848.4 EIW74839.1 - 0.0042 16.1 0.0 0.0042 16.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ArgK PF03308.11 EIW74839.1 - 0.0042 15.9 0.0 0.006 15.3 0.0 1.2 1 0 0 1 1 1 1 ArgK protein PRK PF00485.13 EIW74839.1 - 0.0043 16.6 0.0 0.0049 16.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 EIW74839.1 - 0.0044 16.1 0.0 0.0066 15.5 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin NB-ARC PF00931.17 EIW74839.1 - 0.017 14.0 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.1 EIW74839.1 - 0.019 15.7 0.1 0.031 15.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EIW74839.1 - 0.02 14.4 0.0 0.028 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EIW74839.1 - 0.025 14.0 0.0 0.052 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain TrwB_AAD_bind PF10412.4 EIW74839.1 - 0.04 12.5 0.0 0.057 12.0 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain CbiA PF01656.18 EIW74839.1 - 0.043 13.2 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.1 EIW74839.1 - 0.061 13.1 0.1 0.095 12.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain Miro PF08477.8 EIW74839.1 - 0.063 13.7 0.0 0.11 13.0 0.0 1.4 1 1 0 1 1 1 0 Miro-like protein AAA_14 PF13173.1 EIW74839.1 - 0.065 13.1 0.0 0.097 12.5 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EIW74839.1 - 0.075 13.3 0.1 0.15 12.3 0.0 1.5 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EIW74839.1 - 0.083 12.5 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_19 PF13245.1 EIW74839.1 - 0.091 12.5 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_15 PF13175.1 EIW74839.1 - 0.1 11.6 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain UPF0079 PF02367.12 EIW74839.1 - 0.11 12.1 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 EIW74839.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 EIW74839.1 - 0.13 11.2 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain Bac_rhamnosid PF05592.6 EIW74840.1 - 1e-30 106.4 0.1 1.3e-28 99.5 0.2 2.2 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 EIW74840.1 - 0.004 15.9 1.6 0.0063 15.2 1.1 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Trehalase PF01204.13 EIW74840.1 - 0.01 14.5 1.1 0.015 14.0 0.7 1.2 1 0 0 1 1 1 1 Trehalase OTU PF02338.14 EIW74841.1 - 2.1e-13 50.8 0.0 4.1e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Nucleo_P87 PF07267.6 EIW74841.1 - 3.1 6.3 9.4 14 4.1 0.0 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 AAA PF00004.24 EIW74842.1 - 1.9e-55 186.6 0.0 1.2e-43 148.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EIW74842.1 - 5.4e-22 77.6 0.1 1.2e-21 76.5 0.1 1.6 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EIW74842.1 - 3e-10 40.3 0.1 0.002 18.1 0.0 3.8 2 1 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EIW74842.1 - 1.9e-08 35.1 0.0 0.0077 17.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIW74842.1 - 2.2e-06 27.8 0.1 0.17 12.0 0.0 3.2 2 1 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EIW74842.1 - 4.2e-06 25.9 0.0 0.0018 17.3 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EIW74842.1 - 4.6e-06 26.6 0.0 0.0085 16.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EIW74842.1 - 5.4e-06 26.0 1.4 0.0039 16.8 0.0 3.1 3 0 0 3 3 2 1 Part of AAA domain IstB_IS21 PF01695.12 EIW74842.1 - 7e-06 25.5 0.0 0.054 12.9 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein NACHT PF05729.7 EIW74842.1 - 9.5e-06 25.3 0.1 0.28 10.8 0.0 3.5 3 0 0 3 3 3 2 NACHT domain AAA_18 PF13238.1 EIW74842.1 - 2.8e-05 24.4 0.0 0.18 12.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EIW74842.1 - 3e-05 23.9 0.0 0.022 14.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIW74842.1 - 3.5e-05 23.9 0.0 0.23 11.6 0.0 2.5 2 0 0 2 2 2 2 RNA helicase TIP49 PF06068.8 EIW74842.1 - 3.6e-05 22.6 0.2 0.13 10.9 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_5 PF07728.9 EIW74842.1 - 4.8e-05 23.1 0.0 0.32 10.7 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EIW74842.1 - 5.2e-05 23.1 0.0 0.02 14.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EIW74842.1 - 7.7e-05 22.1 1.5 1.1 8.5 0.1 3.8 2 2 1 4 4 4 2 AAA domain Sigma54_activat PF00158.21 EIW74842.1 - 0.00088 18.7 0.0 0.18 11.2 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.7 EIW74842.1 - 0.0009 18.3 0.0 0.088 11.8 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin MobB PF03205.9 EIW74842.1 - 0.00091 18.9 0.1 0.035 13.8 0.0 3.0 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 EIW74842.1 - 0.0013 17.7 0.0 0.067 12.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_30 PF13604.1 EIW74842.1 - 0.0013 18.3 4.2 0.003 17.1 0.1 2.7 3 0 0 3 3 2 1 AAA domain DUF2075 PF09848.4 EIW74842.1 - 0.0017 17.4 0.0 0.42 9.5 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EIW74842.1 - 0.0021 16.9 0.2 0.54 9.0 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_24 PF13479.1 EIW74842.1 - 0.0026 17.3 0.3 2.4 7.6 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EIW74842.1 - 0.0029 17.6 0.1 1.2 9.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EIW74842.1 - 0.0034 16.5 0.4 0.2 10.7 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 EIW74842.1 - 0.0041 16.8 0.1 0.57 9.8 0.0 2.4 2 0 0 2 2 2 1 NTPase ABC_tran PF00005.22 EIW74842.1 - 0.0049 17.1 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 1 ABC transporter PhoH PF02562.11 EIW74842.1 - 0.005 16.0 1.1 0.69 9.0 0.1 2.7 3 0 0 3 3 2 1 PhoH-like protein AAA_31 PF13614.1 EIW74842.1 - 0.0056 16.6 0.0 0.69 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EIW74842.1 - 0.0073 15.9 0.0 0.65 9.5 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EIW74842.1 - 0.0081 15.8 0.0 6.4 6.4 0.0 2.9 2 1 1 3 3 3 0 Archaeal ATPase Cytidylate_kin2 PF13189.1 EIW74842.1 - 0.011 15.7 0.0 0.034 14.0 0.0 1.8 1 0 0 1 1 1 0 Cytidylate kinase-like family Bac_DnaA PF00308.13 EIW74842.1 - 0.011 15.3 0.0 0.49 10.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein KaiC PF06745.8 EIW74842.1 - 0.012 14.7 0.2 1.9 7.5 0.0 2.6 3 0 0 3 3 2 0 KaiC Viral_helicase1 PF01443.13 EIW74842.1 - 0.014 14.9 0.0 0.11 12.0 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 EIW74842.1 - 0.014 15.0 0.1 5.3 6.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 EIW74842.1 - 0.015 14.2 0.0 0.41 9.5 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein SKI PF01202.17 EIW74842.1 - 0.015 15.1 0.1 0.12 12.1 0.0 2.3 2 0 0 2 2 2 0 Shikimate kinase Parvo_NS1 PF01057.12 EIW74842.1 - 0.017 14.0 0.1 2.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 KTI12 PF08433.5 EIW74842.1 - 0.057 12.6 0.1 1.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 APS_kinase PF01583.15 EIW74842.1 - 0.063 12.9 0.1 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Adenylylsulphate kinase ATP_bind_1 PF03029.12 EIW74842.1 - 0.21 11.0 0.5 0.68 9.4 0.0 2.0 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Hydrophobin PF01185.13 EIW74843.1 - 0.027 14.9 6.3 0.2 12.1 4.8 1.9 1 1 1 2 2 2 0 Fungal hydrophobin TRI5 PF06330.6 EIW74844.1 - 2.9e-17 62.3 0.0 3.4e-17 62.1 0.0 1.0 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) AAA_16 PF13191.1 EIW74845.1 - 9.9e-06 25.6 0.0 1.2e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EIW74845.1 - 0.00011 21.8 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EIW74845.1 - 0.00012 22.2 0.0 0.0004 20.5 0.0 1.7 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EIW74845.1 - 0.00044 19.3 0.0 0.0005 19.2 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin RNA_helicase PF00910.17 EIW74845.1 - 0.00083 19.5 0.0 0.0012 19.0 0.0 1.2 1 0 0 1 1 1 1 RNA helicase ArgK PF03308.11 EIW74845.1 - 0.0014 17.4 0.0 0.0014 17.4 0.0 1.0 1 0 0 1 1 1 1 ArgK protein ABC_tran PF00005.22 EIW74845.1 - 0.0029 17.9 0.0 0.0035 17.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter Arch_ATPase PF01637.13 EIW74845.1 - 0.0077 15.9 0.0 0.0081 15.8 0.0 1.0 1 0 0 1 1 1 1 Archaeal ATPase AAA_19 PF13245.1 EIW74845.1 - 0.015 15.0 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EIW74845.1 - 0.019 14.3 0.0 0.019 14.3 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein Parvo_NS1 PF01057.12 EIW74845.1 - 0.022 13.6 0.0 0.027 13.3 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2075 PF09848.4 EIW74845.1 - 0.025 13.5 0.0 0.028 13.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF258 PF03193.11 EIW74845.1 - 0.025 13.7 0.0 0.025 13.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RuvB_N PF05496.7 EIW74845.1 - 0.029 13.4 0.0 0.034 13.1 0.0 1.1 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus APS_kinase PF01583.15 EIW74845.1 - 0.031 13.9 0.0 0.04 13.5 0.0 1.1 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.17 EIW74845.1 - 0.04 12.7 0.0 0.042 12.7 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.1 EIW74845.1 - 0.043 13.1 0.0 0.045 13.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EIW74845.1 - 0.055 13.6 0.0 0.084 13.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EIW74845.1 - 0.056 12.6 0.0 0.064 12.4 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein MMR_HSR1 PF01926.18 EIW74845.1 - 0.058 13.3 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase KTI12 PF08433.5 EIW74845.1 - 0.059 12.5 0.0 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 EIW74845.1 - 0.061 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIW74845.1 - 0.063 13.5 0.0 0.12 12.7 0.0 1.4 2 0 0 2 2 1 0 AAA domain AAA_17 PF13207.1 EIW74845.1 - 0.065 14.0 0.0 0.1 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EIW74845.1 - 0.072 12.8 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EIW74845.1 - 0.073 12.5 0.0 0.083 12.3 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 EIW74845.1 - 0.075 12.5 0.0 0.088 12.3 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EIW74845.1 - 0.088 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 EIW74845.1 - 0.12 11.9 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 P-loop containing region of AAA domain ADK PF00406.17 EIW74845.1 - 0.12 12.2 0.0 0.37 10.6 0.0 1.7 2 0 0 2 2 2 0 Adenylate kinase Miro PF08477.8 EIW74845.1 - 0.13 12.7 0.0 0.21 12.1 0.0 1.2 1 0 0 1 1 1 0 Miro-like protein Mg_chelatase PF01078.16 EIW74845.1 - 0.14 11.3 0.1 0.36 9.9 0.0 1.6 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI Sugar_tr PF00083.19 EIW74847.1 - 3.4e-18 65.4 22.2 2.2e-16 59.4 15.4 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW74847.1 - 2.7e-17 62.5 50.1 3.7e-11 42.3 27.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ICMT PF04140.9 EIW74849.1 - 4.6e-16 58.7 0.1 3.4e-15 55.9 0.1 2.1 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIW74849.1 - 1.2e-11 44.5 0.2 1.5e-09 37.9 0.0 2.3 2 0 0 2 2 2 2 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EIW74849.1 - 0.0017 16.9 0.0 0.0031 16.0 0.0 1.4 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DLH PF01738.13 EIW74850.1 - 1.6e-23 83.1 0.0 1.8e-23 82.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EIW74850.1 - 5e-07 29.5 0.0 7.2e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EIW74850.1 - 0.024 13.5 0.0 0.033 13.0 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 EIW74850.1 - 0.036 13.9 0.0 4.4 7.1 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family HET PF06985.6 EIW74851.1 - 3.7e-19 69.2 6.0 1.3e-16 61.0 0.4 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ICMT PF04140.9 EIW74852.1 - 1.4e-14 54.0 0.3 6.7e-14 51.8 0.1 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIW74852.1 - 1.3e-11 44.5 2.0 1.8e-09 37.6 0.7 2.4 2 0 0 2 2 2 2 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EIW74852.1 - 1.1e-06 27.5 0.0 1.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Lip_A_acyltrans PF03279.8 EIW74852.1 - 0.18 10.6 1.5 0.32 9.8 0.2 1.9 2 0 0 2 2 2 0 Bacterial lipid A biosynthesis acyltransferase F-box-like PF12937.2 EIW74853.1 - 6.4e-07 29.0 0.0 4.5e-06 26.2 0.0 2.5 1 1 0 1 1 1 1 F-box-like PCI PF01399.22 EIW74854.1 - 2.3e-11 43.9 0.0 7.2e-11 42.3 0.0 1.9 2 0 0 2 2 2 1 PCI domain EF-hand_1 PF00036.27 EIW74855.1 - 0.024 13.9 0.1 0.14 11.5 0.1 2.4 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.1 EIW74855.1 - 0.08 12.8 0.0 0.37 10.8 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain UPF0184 PF03670.8 EIW74855.1 - 0.59 10.3 4.1 53 4.0 0.1 3.6 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0184) EF-hand_6 PF13405.1 EIW74857.1 - 0.0065 16.2 0.0 0.019 14.8 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 EIW74857.1 - 0.017 14.3 0.1 0.05 12.9 0.1 1.8 1 0 0 1 1 1 0 EF hand DSX_dimer PF08828.5 EIW74857.1 - 0.032 13.7 0.5 0.085 12.4 0.0 2.0 2 0 0 2 2 2 0 Doublesex dimerisation domain Colicin_M PF14859.1 EIW74857.1 - 0.048 12.5 0.0 0.11 11.4 0.0 1.5 1 0 0 1 1 1 0 Colicin M SlyX PF04102.7 EIW74857.1 - 0.073 13.4 4.8 0.2 12.0 0.0 3.4 4 0 0 4 4 4 0 SlyX EF-hand_5 PF13202.1 EIW74857.1 - 0.087 12.2 0.2 0.26 10.6 0.2 1.8 1 0 0 1 1 1 0 EF hand Unstab_antitox PF09720.5 EIW74857.1 - 0.31 10.7 4.0 0.29 10.8 0.3 2.9 3 0 0 3 3 3 0 Putative addiction module component V-SNARE PF05008.10 EIW74857.1 - 0.6 10.2 2.8 1.8 8.8 0.0 3.2 4 0 0 4 4 4 0 Vesicle transport v-SNARE protein N-terminus Myb_DNA-binding PF00249.26 EIW74858.1 - 6.4e-16 58.1 0.2 5.5e-09 35.9 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIW74858.1 - 1.5e-10 40.9 0.1 5.3e-05 23.2 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain FA_hydroxylase PF04116.8 EIW74859.1 - 9.3e-15 55.0 24.6 1.8e-14 54.1 13.6 2.2 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Kua-UEV1_localn PF10520.4 EIW74859.1 - 0.0075 15.9 0.4 0.0075 15.9 0.2 2.5 1 1 2 3 3 3 1 Kua-ubiquitin conjugating enzyme hybrid localisation domain SNF2_N PF00176.18 EIW74860.1 - 8.3e-38 129.8 0.0 1.5e-37 129.0 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.1 EIW74860.1 - 5.9e-08 32.2 10.1 1e-07 31.5 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW74860.1 - 6e-08 32.3 10.7 1.1e-07 31.5 7.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIW74860.1 - 6.4e-07 28.9 10.6 1.2e-06 28.0 7.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW74860.1 - 1.9e-06 27.7 11.9 3.4e-06 26.9 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW74860.1 - 2.7e-06 26.9 10.7 4.7e-06 26.2 7.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EIW74860.1 - 0.0025 17.8 9.3 0.01 15.9 6.5 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger Prok-RING_4 PF14447.1 EIW74860.1 - 0.0027 17.2 4.8 0.0069 15.9 3.3 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 EIW74860.1 - 0.015 15.0 1.4 0.037 13.8 1.0 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EIW74860.1 - 0.072 12.9 5.6 0.29 10.9 3.9 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger VWC PF00093.13 EIW74860.1 - 0.28 11.3 8.0 0.59 10.2 5.5 1.5 1 0 0 1 1 1 0 von Willebrand factor type C domain zf-C3HC4_4 PF15227.1 EIW74860.1 - 0.35 10.7 10.3 0.68 9.8 7.2 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EIW74860.1 - 0.49 10.1 5.7 1.4 8.6 3.9 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 EIW74860.1 - 1.3 8.7 14.3 77 2.9 9.9 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 EIW74860.1 - 9.1 5.8 7.3 7.2 6.2 3.8 1.8 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit Methyltransf_23 PF13489.1 EIW74861.1 - 7.6e-10 38.7 0.0 1.2e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW74861.1 - 6.1e-08 32.0 0.0 4e-07 29.3 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EIW74861.1 - 1.2e-06 28.1 0.0 4.2e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW74861.1 - 6e-05 23.4 0.0 0.00011 22.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW74861.1 - 7.9e-05 22.9 0.0 0.00015 22.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW74861.1 - 0.00039 20.9 0.0 0.0023 18.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW74861.1 - 0.02 14.9 0.0 0.11 12.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EIW74861.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) p450 PF00067.17 EIW74862.1 - 8.3e-75 252.0 0.0 1e-74 251.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_31 PF13847.1 EIW74863.1 - 4.4e-09 36.0 0.0 2.1e-08 33.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW74863.1 - 2.4e-06 27.3 0.0 4.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW74863.1 - 5.2e-05 23.6 0.0 8.8e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW74863.1 - 0.0026 16.9 0.0 0.017 14.2 0.0 2.0 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 EIW74863.1 - 0.0089 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_18 PF12847.2 EIW74863.1 - 0.012 16.2 0.0 0.13 12.8 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EIW74863.1 - 0.039 14.3 0.0 0.1 12.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EIW74863.1 - 0.047 13.6 0.0 0.062 13.2 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EIW74863.1 - 0.083 12.9 0.0 2.4 8.2 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain DUF3349 PF11829.3 EIW74864.1 - 0.14 12.6 0.1 0.29 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) Anticodon_1 PF08264.8 EIW74866.1 - 2.7e-11 43.4 0.0 5.6e-11 42.4 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA DUF1840 PF08895.6 EIW74866.1 - 0.012 15.6 0.2 0.021 14.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) RQC PF09382.5 EIW74867.1 - 2.6e-11 43.1 0.1 4.7e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 RQC domain DEAD PF00270.24 EIW74868.1 - 3.3e-06 26.7 0.1 3.5e-06 26.6 0.1 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.9 EIW74868.1 - 0.073 11.6 0.0 0.073 11.6 0.0 1.0 1 0 0 1 1 1 0 Type IV secretory system Conjugative DNA transfer FAD_binding_3 PF01494.14 EIW74869.1 - 8.3e-20 71.1 0.0 1.3e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain E1-E2_ATPase PF00122.15 EIW74869.1 - 3.5e-18 65.5 6.7 4.1e-12 45.6 0.0 3.2 3 1 1 4 4 4 2 E1-E2 ATPase Cation_ATPase_N PF00690.21 EIW74869.1 - 2.3e-06 26.9 0.0 8.1e-06 25.2 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.21 EIW74869.1 - 2.7e-05 24.7 0.0 5.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Histone PF00125.19 EIW74870.1 - 0.13 12.4 0.0 1.7 8.8 0.0 2.2 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 SDA1 PF05285.7 EIW74871.1 - 0.047 12.9 8.4 0.15 11.3 5.8 1.8 1 1 0 1 1 1 0 SDA1 Cnd3 PF12719.2 EIW74872.1 - 2.4e-66 223.7 4.2 4.5e-66 222.8 0.2 2.8 4 0 0 4 4 4 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EIW74872.1 - 3.8e-05 23.8 6.0 0.69 10.2 0.0 4.4 4 0 0 4 4 4 3 HEAT repeats HEAT PF02985.17 EIW74872.1 - 0.00017 21.3 0.1 0.1 12.7 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat DUF2783 PF10932.3 EIW74872.1 - 0.026 14.0 0.4 0.18 11.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2783) HEAT_EZ PF13513.1 EIW74872.1 - 3.7 8.1 6.8 5.3 7.6 0.1 4.2 4 0 0 4 4 4 0 HEAT-like repeat Ribosomal_L18ae PF01775.12 EIW74873.1 - 4.7e-18 65.2 0.1 1.2e-17 63.8 0.1 1.7 1 1 0 1 1 1 1 Ribosomal L18ae/LX protein domain zf-primase PF09329.6 EIW74874.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Primase zinc finger E1-E2_ATPase PF00122.15 EIW74876.1 - 8e-13 47.9 0.2 2.4e-06 26.7 1.0 3.0 1 1 1 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.21 EIW74876.1 - 0.0042 17.5 0.0 0.0069 16.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIW74876.1 - 0.0048 17.0 0.0 0.0092 16.1 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Tet_JBP PF12851.2 EIW74881.1 - 0.0002 20.6 0.0 0.00025 20.4 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Pkinase PF00069.20 EIW74882.1 - 9.8e-33 113.3 0.0 4.9e-15 55.3 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW74882.1 - 8.4e-16 57.8 0.0 1.1e-12 47.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EIW74882.1 - 3.1e-07 30.4 0.2 8.6e-07 28.9 0.1 1.8 1 1 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EIW74882.1 - 0.014 14.3 0.0 0.028 13.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DUF1180 PF06679.7 EIW74883.1 - 0.025 14.4 0.2 0.046 13.5 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1180) Pkinase PF00069.20 EIW74885.1 - 7.5e-56 189.1 0.0 8.7e-56 188.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW74885.1 - 3.6e-35 121.2 0.0 4.3e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW74885.1 - 4.4e-05 22.5 0.0 0.00062 18.8 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 EIW74885.1 - 0.00063 18.8 0.0 0.00084 18.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EIW74885.1 - 0.01 15.1 0.2 0.021 14.1 0.2 1.5 1 1 0 1 1 1 0 RIO1 family APH PF01636.18 EIW74885.1 - 0.026 14.2 0.0 3.2 7.4 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Cyclin_N PF00134.18 EIW74886.1 - 1.6e-11 43.8 0.0 2.1e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EIW74886.1 - 1.2e-09 38.7 0.0 1.5e-09 38.4 0.0 1.2 1 0 0 1 1 1 1 Cyclin COG2 PF06148.6 EIW74887.1 - 7.2e-10 38.8 0.2 1.4e-09 37.9 0.2 1.4 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 BTB PF00651.26 EIW74887.1 - 1.5e-06 28.1 0.0 4.9e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 BTB/POZ domain DUF4388 PF14332.1 EIW74887.1 - 0.1 12.4 0.0 0.74 9.7 0.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4388) Sad1_UNC PF07738.8 EIW74888.1 - 6.2e-16 58.4 0.0 2.9e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal DivIC PF04977.10 EIW74888.1 - 0.0038 16.6 0.2 0.0063 15.9 0.1 1.3 1 0 0 1 1 1 1 Septum formation initiator Ribosomal_L18ae PF01775.12 EIW74889.1 - 8.2e-26 90.3 0.3 1e-25 90.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain Trehalase PF01204.13 EIW74891.1 - 1.4e-29 103.1 3.1 8.5e-12 44.4 0.1 3.1 3 0 0 3 3 3 3 Trehalase RPN7 PF10602.4 EIW74892.1 - 1.8e-15 56.7 0.0 3.1e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EIW74892.1 - 0.00096 19.4 0.1 0.0042 17.3 0.0 2.1 3 0 0 3 3 3 1 PCI domain DUF659 PF04937.10 EIW74896.1 - 4.1e-10 39.3 0.0 7.6e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Dimer_Tnp_hAT PF05699.9 EIW74896.1 - 1.2e-05 24.8 0.3 3.3e-05 23.4 0.2 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ICMT PF04140.9 EIW74897.1 - 9.8e-16 57.7 0.4 2.8e-14 53.0 0.3 2.3 1 1 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIW74897.1 - 3.3e-13 49.6 0.7 3e-12 46.5 0.3 2.2 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EIW74897.1 - 5.9e-07 28.3 0.0 9.4e-07 27.7 0.0 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PROCN PF08083.6 EIW74897.1 - 0.071 11.5 0.0 0.096 11.1 0.0 1.1 1 0 0 1 1 1 0 PROCN (NUC071) domain TFIIA PF03153.8 EIW74898.1 - 0.0011 18.9 12.7 0.0011 18.9 8.8 1.7 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit EF-hand_1 PF00036.27 EIW74898.1 - 0.015 14.5 0.0 0.045 13.0 0.0 1.8 1 0 0 1 1 1 0 EF hand PBP_sp32 PF07222.7 EIW74898.1 - 2.4 7.2 16.1 5.6 6.0 11.1 1.5 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DDHD PF02862.12 EIW74898.1 - 8.4 6.1 9.1 22 4.7 6.3 1.7 1 0 0 1 1 1 0 DDHD domain MR_MLE_C PF13378.1 EIW74899.1 - 4.9e-20 71.5 0.0 8.3e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EIW74899.1 - 9.8e-12 45.2 0.0 2e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EIW74899.1 - 5.3e-09 36.0 0.0 8.5e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain STE3 PF02076.10 EIW74900.1 - 1.2e-101 339.5 13.3 1.4e-101 339.2 9.2 1.0 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.10 EIW74901.1 - 8.8e-49 166.0 7.9 1.3e-48 165.4 5.5 1.3 1 0 0 1 1 1 1 Pheromone A receptor SF-assemblin PF06705.6 EIW74902.1 - 0.0026 16.9 0.2 0.0038 16.4 0.2 1.1 1 0 0 1 1 1 1 SF-assemblin/beta giardin Sld5 PF05916.6 EIW74902.1 - 0.13 12.5 0.1 0.27 11.5 0.1 1.5 1 0 0 1 1 1 0 GINS complex protein CHASE3 PF05227.8 EIW74902.1 - 0.23 11.1 4.4 0.26 10.9 0.4 2.1 1 1 1 2 2 2 0 CHASE3 domain AF-4 PF05110.8 EIW74902.1 - 4.2 5.1 13.2 5.5 4.7 9.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GST_N_3 PF13417.1 EIW74903.1 - 3.2e-07 30.4 0.0 7.7e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW74903.1 - 9.2e-05 22.2 0.8 0.00018 21.3 0.6 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW74903.1 - 0.0071 16.3 0.0 0.045 13.7 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIW74904.1 - 7.9e-10 38.8 0.0 1.5e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW74904.1 - 8.7e-06 25.5 0.5 1.2e-05 25.0 0.4 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW74904.1 - 0.00015 21.9 0.0 0.00032 20.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW74904.1 - 0.0006 19.7 0.0 0.00094 19.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW74904.1 - 0.0064 16.4 0.0 0.012 15.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW74904.1 - 0.019 15.4 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain STE3 PF02076.10 EIW74906.1 - 1.7e-103 345.6 11.5 2e-103 345.4 8.0 1.0 1 0 0 1 1 1 1 Pheromone A receptor 7TM_GPCR_Srt PF10321.4 EIW74906.1 - 0.0026 16.5 1.8 0.0026 16.5 1.2 1.7 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srt DUF4243 PF14027.1 EIW74908.1 - 1.1e-78 265.0 0.0 1.9e-78 264.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF4243) DUF4243 PF14027.1 EIW74909.1 - 3.7e-73 246.8 0.3 4.6e-73 246.5 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Tubulin_3 PF14881.1 EIW74910.1 - 1.3e-29 102.9 0.0 2.5e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 EIW74910.1 - 8.6e-29 99.9 0.0 1.6e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 EIW74910.1 - 3.5e-06 27.0 0.0 0.00014 21.7 0.0 2.2 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain adh_short PF00106.20 EIW74911.1 - 5.8e-23 81.6 3.0 8.3e-23 81.1 2.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW74911.1 - 1.2e-11 44.6 2.2 2.3e-11 43.6 1.5 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIW74911.1 - 2e-07 31.1 0.4 1.8e-06 28.1 0.2 2.1 1 1 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 EIW74911.1 - 6.9e-05 22.4 0.2 0.00018 21.0 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase adh_short_C2 PF13561.1 EIW74911.1 - 6.9e-05 22.7 0.2 0.0001 22.1 0.2 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EIW74911.1 - 0.00064 19.2 0.0 0.0046 16.4 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family YjeF_N PF03853.10 EIW74911.1 - 0.0049 16.4 1.2 0.0089 15.6 0.1 1.8 2 0 0 2 2 2 1 YjeF-related protein N-terminus 3HCDH_N PF02737.13 EIW74911.1 - 0.0056 16.3 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EIW74911.1 - 0.0084 15.2 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.10 EIW74911.1 - 0.016 14.7 0.1 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein NAD_binding_7 PF13241.1 EIW74911.1 - 0.034 14.4 0.1 0.077 13.2 0.1 1.4 1 1 0 1 1 1 0 Putative NAD(P)-binding Glyco_transf_4 PF13439.1 EIW74911.1 - 0.039 13.6 0.0 0.092 12.4 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 TrkA_N PF02254.13 EIW74911.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DUF2163 PF09931.4 EIW74911.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2163) DUF3814 PF12769.2 EIW74912.1 - 0.13 12.4 3.3 0.19 11.8 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3814) Metallophos PF00149.23 EIW74913.1 - 2.6e-42 144.5 0.1 3.2e-42 144.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4243 PF14027.1 EIW74914.1 - 2.9e-82 276.7 0.1 3.7e-82 276.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Pox_A14 PF05767.7 EIW74915.1 - 0.01 15.7 1.5 0.01 15.7 1.0 4.0 2 2 2 4 4 4 0 Poxvirus virion envelope protein A14 TRIQK PF15168.1 EIW74915.1 - 0.022 14.6 0.4 0.022 14.6 0.3 2.2 3 0 0 3 3 3 0 Triple QxxK/R motif-containing protein family Glyco_hydro_14 PF01373.12 EIW74915.1 - 0.08 11.6 0.2 0.11 11.1 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 14 CRPA PF05745.6 EIW74915.1 - 0.11 12.3 0.3 0.11 12.3 0.2 2.8 3 0 0 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) DUF202 PF02656.10 EIW74915.1 - 9.7 6.4 14.7 3.8 7.8 0.4 3.8 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Methyltransf_11 PF08241.7 EIW74916.1 - 9.9e-07 29.1 0.0 1.7e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW74916.1 - 0.0002 21.1 0.0 0.00035 20.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW74916.1 - 0.0019 17.3 0.0 0.0051 15.9 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EIW74916.1 - 0.0075 15.8 0.0 0.028 14.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIW74916.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_25 PF13649.1 EIW74916.1 - 0.029 14.7 0.0 0.061 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EIW74917.1 - 8e-10 38.6 0.0 2.4e-09 37.0 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW74917.1 - 1.5e-08 34.9 0.0 2.9e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW74917.1 - 2.4e-08 33.6 0.0 8.6e-08 31.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW74917.1 - 1.5e-05 25.0 0.0 8.4e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW74917.1 - 6.5e-05 23.2 0.0 0.00016 21.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW74917.1 - 0.00029 20.0 0.0 0.0021 17.2 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EIW74917.1 - 0.00097 19.5 0.0 0.0023 18.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EIW74917.1 - 0.0022 18.0 0.0 0.0038 17.2 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase GCD14 PF08704.5 EIW74917.1 - 0.037 13.5 0.0 0.081 12.4 0.0 1.5 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.8 EIW74917.1 - 0.06 12.4 0.0 0.63 9.0 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EIW74917.1 - 0.075 13.6 0.0 0.33 11.5 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain FCD PF07729.7 EIW74917.1 - 0.092 13.0 0.1 0.42 10.9 0.1 2.0 1 1 1 2 2 2 0 FCD domain Methyltransf_8 PF05148.10 EIW74917.1 - 0.11 12.1 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase PQQ_2 PF13360.1 EIW74921.1 - 0.016 14.7 0.0 0.12 11.7 0.0 2.2 2 0 0 2 2 2 0 PQQ-like domain NACHT PF05729.7 EIW74922.1 - 9e-12 44.9 0.1 1.7e-11 44.0 0.1 1.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW74922.1 - 7.5e-10 39.0 0.1 1.2e-09 38.4 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW74922.1 - 3.5e-06 27.2 0.1 9.1e-06 25.8 0.0 1.8 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIW74922.1 - 0.00023 21.3 0.0 0.00052 20.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase APS_kinase PF01583.15 EIW74922.1 - 0.00039 20.1 0.3 0.00083 19.0 0.0 1.6 2 0 0 2 2 2 1 Adenylylsulphate kinase NTPase_1 PF03266.10 EIW74922.1 - 0.0017 18.1 0.0 0.0028 17.3 0.0 1.4 1 0 0 1 1 1 1 NTPase AAA_17 PF13207.1 EIW74922.1 - 0.0019 18.9 0.1 0.0046 17.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EIW74922.1 - 0.0022 17.5 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family KaiC PF06745.8 EIW74922.1 - 0.0043 16.2 0.0 0.044 12.8 0.0 2.0 2 0 0 2 2 2 1 KaiC Arch_ATPase PF01637.13 EIW74922.1 - 0.0049 16.5 0.0 0.008 15.9 0.0 1.3 1 1 0 1 1 1 1 Archaeal ATPase AAA_29 PF13555.1 EIW74922.1 - 0.0051 16.3 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EIW74922.1 - 0.006 15.7 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin ABC_tran PF00005.22 EIW74922.1 - 0.0094 16.2 0.0 0.024 14.9 0.0 1.5 1 1 0 1 1 1 1 ABC transporter DUF2075 PF09848.4 EIW74922.1 - 0.011 14.7 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF258 PF03193.11 EIW74922.1 - 0.016 14.3 0.1 0.054 12.6 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 EIW74922.1 - 0.018 15.3 0.0 0.03 14.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain T2SE PF00437.15 EIW74922.1 - 0.022 13.6 0.0 0.039 12.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein NB-ARC PF00931.17 EIW74922.1 - 0.027 13.3 0.0 0.088 11.6 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.24 EIW74922.1 - 0.028 14.6 0.0 0.17 12.0 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.9 EIW74922.1 - 0.029 13.3 0.0 0.048 12.6 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain Sigma54_activ_2 PF14532.1 EIW74922.1 - 0.036 14.1 0.0 0.077 13.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Gp37_Gp68 PF07505.6 EIW74922.1 - 0.047 12.8 0.0 0.058 12.5 0.0 1.2 1 0 0 1 1 1 0 Phage protein Gp37/Gp68 Sigma54_activat PF00158.21 EIW74922.1 - 0.052 13.0 0.0 0.085 12.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.1 EIW74922.1 - 0.055 13.3 0.2 0.091 12.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EIW74922.1 - 0.08 12.4 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.1 EIW74922.1 - 0.089 12.5 0.0 0.25 11.1 0.0 1.7 2 0 0 2 2 1 0 Part of AAA domain ArgK PF03308.11 EIW74922.1 - 0.1 11.3 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 ArgK protein AAA_10 PF12846.2 EIW74922.1 - 0.17 11.2 0.6 0.66 9.3 0.4 2.2 1 1 0 1 1 1 0 AAA-like domain SAE2 PF08573.5 EIW74925.1 - 1.6e-18 67.1 9.4 2e-17 63.6 6.5 2.2 1 1 0 1 1 1 1 DNA repair protein endonuclease SAE2/CtIP C-terminus DND1_DSRM PF14709.1 EIW74926.1 - 0.16 12.2 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_16 PF13191.1 EIW74931.1 - 2.5e-07 30.8 0.0 3.1e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EIW74931.1 - 3.8e-06 26.6 0.0 6.5e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EIW74931.1 - 2.2e-05 24.6 0.0 3.5e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EIW74931.1 - 4.7e-05 23.0 0.0 7.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.17 EIW74931.1 - 0.00014 21.9 0.0 0.00024 21.2 0.0 1.4 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.10 EIW74931.1 - 0.0003 20.5 0.0 0.00043 20.0 0.0 1.3 1 0 0 1 1 1 1 NTPase ABC_tran PF00005.22 EIW74931.1 - 0.0014 18.9 0.0 0.0017 18.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter PRK PF00485.13 EIW74931.1 - 0.0014 18.2 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.1 EIW74931.1 - 0.0021 17.5 0.0 0.0038 16.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EIW74931.1 - 0.0036 16.4 0.0 0.0054 15.8 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EIW74931.1 - 0.0043 17.3 0.0 0.0058 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EIW74931.1 - 0.0055 15.9 0.1 0.014 14.5 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Gp37_Gp68 PF07505.6 EIW74931.1 - 0.0057 15.8 0.0 0.006 15.7 0.0 1.2 1 0 0 1 1 1 1 Phage protein Gp37/Gp68 T2SE PF00437.15 EIW74931.1 - 0.0069 15.3 0.0 0.0095 14.8 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF2075 PF09848.4 EIW74931.1 - 0.011 14.7 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 EIW74931.1 - 0.011 16.4 0.1 0.017 15.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain ArgK PF03308.11 EIW74931.1 - 0.012 14.3 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 ArgK protein KaiC PF06745.8 EIW74931.1 - 0.013 14.5 0.0 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 KaiC NB-ARC PF00931.17 EIW74931.1 - 0.017 14.0 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 EIW74931.1 - 0.03 14.0 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_31 PF13614.1 EIW74931.1 - 0.036 14.0 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain CbiA PF01656.18 EIW74931.1 - 0.043 13.2 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain KAP_NTPase PF07693.9 EIW74931.1 - 0.049 12.6 0.1 0.15 10.9 0.0 1.9 2 1 1 3 3 3 0 KAP family P-loop domain AAA_33 PF13671.1 EIW74931.1 - 0.055 13.3 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EIW74931.1 - 0.055 13.0 0.0 0.07 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 EIW74931.1 - 0.067 12.6 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sigma54_activat PF00158.21 EIW74931.1 - 0.082 12.3 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_10 PF12846.2 EIW74931.1 - 0.085 12.2 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain TrwB_AAD_bind PF10412.4 EIW74931.1 - 0.086 11.4 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.9 EIW74931.1 - 0.097 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PIF1 PF05970.9 EIW74931.1 - 0.1 11.5 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase AAA_19 PF13245.1 EIW74931.1 - 0.1 12.3 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain PhoH PF02562.11 EIW74931.1 - 0.1 11.7 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_23 PF13476.1 EIW74931.1 - 0.11 12.7 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 EIW74931.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Torsin NACHT PF05729.7 EIW74932.1 - 4.7e-09 36.1 0.0 1.1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW74932.1 - 2.3e-08 34.2 0.1 6.4e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW74932.1 - 6.2e-05 23.1 0.0 0.00014 21.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EIW74932.1 - 0.00017 21.3 0.0 0.00034 20.3 0.0 1.5 1 0 0 1 1 1 1 Archaeal ATPase APS_kinase PF01583.15 EIW74932.1 - 0.00036 20.2 0.0 0.00063 19.4 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_29 PF13555.1 EIW74932.1 - 0.0017 17.8 0.0 0.0047 16.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 EIW74932.1 - 0.0028 17.7 0.0 0.0059 16.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 EIW74932.1 - 0.0035 16.4 0.0 0.0063 15.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin PRK PF00485.13 EIW74932.1 - 0.0077 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPF0079 PF02367.12 EIW74932.1 - 0.012 15.1 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF258 PF03193.11 EIW74932.1 - 0.024 13.8 0.0 0.047 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 T2SE PF00437.15 EIW74932.1 - 0.025 13.4 0.0 0.042 12.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 EIW74932.1 - 0.03 14.6 0.0 0.075 13.3 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 EIW74932.1 - 0.032 14.5 0.0 0.065 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EIW74932.1 - 0.053 13.2 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 NTPase Sigma54_activ_2 PF14532.1 EIW74932.1 - 0.066 13.2 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain MobB PF03205.9 EIW74932.1 - 0.076 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EIW74932.1 - 0.087 12.6 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EIW74932.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EIW74932.1 - 0.13 11.7 0.1 0.38 10.1 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_19 PF13245.1 EIW74932.1 - 0.16 11.7 0.0 0.52 10.0 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 EIW74932.1 - 0.17 12.7 0.0 0.48 11.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain CbiA PF01656.18 EIW74932.1 - 0.18 11.2 0.0 0.3 10.4 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF2075 PF09848.4 EIW74932.1 - 0.19 10.6 0.0 0.28 10.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EIW74932.1 - 0.2 11.1 0.0 0.36 10.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain TPX2 PF06886.6 EIW74934.1 - 0.0016 18.4 17.6 0.0016 18.4 12.2 3.1 3 0 0 3 3 3 1 Targeting protein for Xklp2 (TPX2) DUF4243 PF14027.1 EIW74935.1 - 4.4e-80 269.6 0.1 5.5e-80 269.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF4218 PF13960.1 EIW74936.1 - 0.00015 21.1 0.0 0.00023 20.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) NCU-G1 PF15065.1 EIW74941.1 - 0.14 10.8 0.5 0.19 10.3 0.3 1.2 1 0 0 1 1 1 0 Lysosomal transcription factor, NCU-G1 FolB PF02152.13 EIW74942.1 - 2.8e-31 108.0 0.0 3.5e-19 69.0 0.0 2.2 2 0 0 2 2 2 2 Dihydroneopterin aldolase Glyco_transf_20 PF00982.16 EIW74943.1 - 3.8e-140 467.5 0.0 5.3e-140 467.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EIW74943.1 - 6e-17 61.3 0.0 1.1e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Glyco_transf_5 PF08323.6 EIW74943.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Starch synthase catalytic domain DUF3488 PF11992.3 EIW74944.1 - 0.41 9.2 7.5 0.57 8.7 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) PepSY_TM_3 PF13706.1 EIW74946.1 - 0.31 10.5 2.1 0.97 8.9 1.5 1.9 1 0 0 1 1 1 0 PepSY-associated TM helix Pkinase PF00069.20 EIW74947.1 - 1.9e-70 237.0 0.2 1.9e-70 237.0 0.1 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW74947.1 - 1.8e-54 184.5 1.1 2.9e-54 183.8 0.1 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 EIW74947.1 - 4e-21 75.2 0.1 9.6e-21 73.9 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EIW74947.1 - 9.4e-07 28.0 0.0 1.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PH PF00169.24 EIW74947.1 - 4.8e-05 23.5 0.9 0.0001 22.4 0.6 1.5 1 0 0 1 1 1 1 PH domain APH PF01636.18 EIW74947.1 - 0.00069 19.4 2.7 0.0073 16.0 0.0 3.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EIW74947.1 - 0.029 13.1 0.1 0.053 12.3 0.1 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 DUF1777 PF08648.7 EIW74947.1 - 0.052 13.2 19.7 0.1 12.3 13.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Ribosomal_S19 PF00203.16 EIW74948.1 - 1.4e-22 79.0 0.0 1.7e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 p450 PF00067.17 EIW74949.1 - 6.4e-35 120.5 0.0 8.5e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_3 PF13738.1 EIW74952.1 - 5.9e-21 75.4 0.0 5.2e-20 72.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIW74952.1 - 1e-14 53.6 0.2 1.7e-13 49.6 0.1 2.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EIW74952.1 - 8.9e-14 51.8 0.0 4.5e-11 43.0 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW74952.1 - 1.2e-06 27.7 0.0 9e-05 21.5 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EIW74952.1 - 3.4e-06 26.9 0.0 0.028 14.1 0.0 2.8 2 1 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EIW74952.1 - 1.2e-05 24.5 0.2 2e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EIW74952.1 - 1.5e-05 25.2 1.0 0.013 15.9 0.1 3.1 4 0 0 4 4 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EIW74952.1 - 4.4e-05 23.5 0.4 0.0076 16.3 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 EIW74952.1 - 7.2e-05 22.7 0.0 0.00017 21.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.16 EIW74952.1 - 8.1e-05 22.2 0.9 0.0043 16.6 0.1 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.2 EIW74952.1 - 0.0003 19.9 0.2 0.00048 19.3 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EIW74952.1 - 0.00037 20.6 0.0 1.6 8.9 0.0 2.9 2 1 0 2 2 2 2 Putative NAD(P)-binding HI0933_like PF03486.9 EIW74952.1 - 0.00047 18.7 1.2 0.00064 18.3 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EIW74952.1 - 0.0013 17.6 0.9 0.051 12.4 0.1 3.0 3 1 0 3 3 3 1 Glucose inhibited division protein A DAO PF01266.19 EIW74952.1 - 0.0017 17.3 0.2 0.37 9.6 0.0 3.4 3 1 0 4 4 4 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW74952.1 - 0.0032 16.3 0.2 0.006 15.4 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.14 EIW74952.1 - 0.011 14.9 0.0 0.23 10.6 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.12 EIW74952.1 - 0.024 13.7 0.0 0.06 12.4 0.0 1.6 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 EIW74952.1 - 0.037 12.6 0.3 0.37 9.3 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.7 EIW74952.1 - 0.073 11.9 0.0 0.75 8.6 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EIW74953.1 - 3.1e-22 79.6 0.0 4.1e-21 75.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIW74953.1 - 4.2e-20 71.4 0.1 2.1e-15 55.9 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EIW74953.1 - 7.5e-15 55.3 0.0 7.8e-12 45.4 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW74953.1 - 7.1e-08 31.7 0.1 5.6e-06 25.5 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EIW74953.1 - 8.9e-07 28.8 0.0 0.0062 16.3 0.0 2.8 2 1 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EIW74953.1 - 9.3e-07 28.2 0.0 6e-06 25.5 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EIW74953.1 - 1.1e-06 28.5 0.0 2.7e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EIW74953.1 - 6.9e-06 26.1 0.0 0.044 13.8 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 EIW74953.1 - 3.2e-05 22.6 0.2 9.9e-05 20.9 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 EIW74953.1 - 9.8e-05 21.4 0.5 0.067 12.0 0.1 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW74953.1 - 0.00014 20.8 0.2 0.00029 19.8 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 EIW74953.1 - 0.0003 21.0 0.0 0.93 9.7 0.0 3.0 3 0 0 3 3 3 1 Putative NAD(P)-binding FAD_oxidored PF12831.2 EIW74953.1 - 0.00039 19.6 0.2 0.00064 18.9 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW74953.1 - 0.0015 18.9 0.1 0.024 15.0 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW74953.1 - 0.0019 17.3 0.0 0.0042 16.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 EIW74953.1 - 0.0064 15.1 0.1 0.21 10.1 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.17 EIW74953.1 - 0.013 14.4 0.1 0.2 10.4 0.0 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EIW74953.1 - 0.018 14.5 0.5 0.063 12.8 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EIW74953.1 - 0.035 13.0 0.0 0.39 9.5 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 EIW74953.1 - 0.13 11.4 0.0 0.71 8.9 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1049 PF06305.6 EIW74954.1 - 0.032 13.7 0.5 0.047 13.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF2363 PF10155.4 EIW74955.1 - 2e-06 27.7 0.0 3.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2363) F-box-like PF12937.2 EIW74957.1 - 1.9e-09 37.1 0.0 5e-09 35.7 0.0 1.7 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EIW74957.1 - 0.0082 15.7 0.8 2.2 8.0 0.1 2.5 2 0 0 2 2 2 2 F-box domain Abhydrolase_3 PF07859.8 EIW74958.1 - 4.1e-23 82.0 0.0 6e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIW74958.1 - 1.2e-09 37.2 0.0 1.7e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EIW74958.1 - 0.0086 15.8 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIW74958.1 - 0.13 11.4 0.1 0.33 10.1 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family TetR_C PF02909.12 EIW74959.1 - 0.032 13.8 0.0 0.088 12.4 0.0 1.7 2 0 0 2 2 2 0 Tetracyclin repressor, C-terminal all-alpha domain DUF3263 PF11662.3 EIW74959.1 - 0.081 12.3 1.0 0.26 10.7 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3263) YwiC PF14256.1 EIW74960.1 - 0.02 14.9 5.7 0.02 14.9 4.0 2.3 2 0 0 2 2 2 0 YwiC-like protein SNARE_assoc PF09335.6 EIW74961.1 - 0.017 15.3 0.1 0.017 15.3 0.1 2.6 2 1 0 2 2 2 0 SNARE associated Golgi protein RhodobacterPufX PF11511.3 EIW74961.1 - 0.071 12.5 0.1 5.2 6.5 0.0 2.8 2 0 0 2 2 2 0 Intrinsic membrane protein PufX DUF1616 PF07760.6 EIW74961.1 - 1.2 8.2 7.0 3.9 6.5 3.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) adh_short PF00106.20 EIW74962.1 - 1.4e-13 51.1 0.0 2.4e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW74962.1 - 4.8e-05 23.0 0.0 0.0001 22.0 0.0 1.5 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 EIW74962.1 - 0.15 12.1 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 EIW74963.1 - 2e-14 53.8 0.1 5.1e-14 52.5 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIW74963.1 - 4.7e-05 23.1 0.1 0.00019 21.1 0.0 2.0 3 0 0 3 3 3 1 KR domain DUF3220 PF11516.3 EIW74968.1 - 0.013 15.4 0.1 0.15 12.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3120) DUF2205 PF10224.4 EIW74968.1 - 0.078 12.5 0.1 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) NPV_P10 PF05531.7 EIW74968.1 - 3.1 8.1 5.3 15 5.9 1.6 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Transposase_21 PF02992.9 EIW74970.1 - 7.5e-10 38.2 0.0 1.9e-09 36.9 0.0 1.6 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIW74970.1 - 0.027 13.9 0.1 0.066 12.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Aldo_ket_red PF00248.16 EIW74974.1 - 3.3e-39 134.3 0.0 3.8e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MarR_2 PF12802.2 EIW74974.1 - 0.054 13.1 0.1 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 MarR family HTH_IclR PF09339.5 EIW74974.1 - 0.14 11.7 0.1 2.9 7.5 0.0 2.4 2 0 0 2 2 2 0 IclR helix-turn-helix domain MFS_1 PF07690.11 EIW74976.1 - 1.6e-42 145.5 35.3 2.5e-42 144.8 20.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2763 PF10961.3 EIW74976.1 - 0.11 12.8 0.3 0.28 11.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) DUF972 PF06156.8 EIW74977.1 - 0.65 10.3 2.5 1.6 9.1 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4618 PF15397.1 EIW74977.1 - 1.1 8.5 2.0 1.7 7.9 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) APG6 PF04111.7 EIW74977.1 - 4.3 6.3 6.4 6.7 5.6 4.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Grp1_Fun34_YaaH PF01184.14 EIW74978.1 - 3.5e-33 114.7 21.0 4.1e-33 114.4 14.6 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Mpv17_PMP22 PF04117.7 EIW74980.1 - 5.1e-23 80.4 0.3 1e-22 79.4 0.2 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF1435 PF07256.7 EIW74980.1 - 0.053 13.4 0.2 4.8 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1435) p450 PF00067.17 EIW74981.1 - 2.5e-69 234.0 0.0 4.6e-69 233.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF1416 PF07210.7 EIW74981.1 - 0.13 11.8 0.1 0.65 9.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1416) DUF4064 PF13273.1 EIW74982.1 - 3.4 7.8 8.5 3.1 7.9 4.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Grp1_Fun34_YaaH PF01184.14 EIW74983.1 - 0.091 12.0 6.3 0.032 13.5 2.3 1.8 2 0 0 2 2 2 0 GPR1/FUN34/yaaH family TPR_11 PF13414.1 EIW74984.1 - 8.5e-20 70.1 17.7 0.00012 21.6 0.1 8.7 8 1 1 9 9 9 6 TPR repeat TPR_16 PF13432.1 EIW74984.1 - 2.1e-16 60.1 23.8 1.7e-05 25.3 0.3 8.4 7 2 2 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIW74984.1 - 3e-12 46.6 12.4 0.0026 18.0 0.2 7.3 7 1 1 8 8 6 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIW74984.1 - 1e-11 43.7 13.2 0.27 11.2 0.0 10.8 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIW74984.1 - 5.4e-11 41.4 5.5 0.011 15.4 0.0 7.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIW74984.1 - 6.6e-10 38.7 4.6 0.028 14.8 0.0 8.1 9 0 0 9 9 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIW74984.1 - 6.7e-10 38.7 14.4 0.019 14.8 0.0 8.5 8 2 2 10 10 9 3 Tetratricopeptide repeat Apc3 PF12895.2 EIW74984.1 - 3.2e-07 30.3 6.6 1 9.5 0.1 6.4 6 1 0 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EIW74984.1 - 1.5e-06 27.5 0.9 31 4.6 0.0 8.2 10 0 0 10 10 10 0 Tetratricopeptide repeat TPR_17 PF13431.1 EIW74984.1 - 7.9e-06 25.6 3.7 2.5 8.5 0.0 6.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIW74984.1 - 1e-05 24.9 11.1 1.2 8.8 0.0 8.3 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIW74984.1 - 5.8e-05 23.3 25.0 6.7 7.6 0.2 10.4 7 3 6 13 13 13 1 Tetratricopeptide repeat TPR_15 PF13429.1 EIW74984.1 - 0.00015 20.9 3.4 0.089 11.8 0.0 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EIW74984.1 - 0.0008 19.6 0.7 0.23 11.6 0.1 2.6 2 0 0 2 2 2 1 Alkyl sulfatase dimerisation TPR_9 PF13371.1 EIW74984.1 - 0.012 15.3 10.1 0.074 12.9 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat SNAP PF14938.1 EIW74984.1 - 0.047 12.8 1.0 0.44 9.6 0.0 2.4 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_20 PF14561.1 EIW74984.1 - 0.06 13.4 0.4 0.06 13.4 0.3 3.5 4 0 0 4 4 3 0 Tetratricopeptide repeat TSC21 PF15217.1 EIW74984.1 - 0.075 12.7 0.2 0.23 11.1 0.0 1.8 2 0 0 2 2 2 0 TSC21 family TPR_4 PF07721.9 EIW74984.1 - 0.66 10.5 7.0 27 5.5 0.9 5.6 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EIW74984.1 - 1 9.3 15.0 25 4.9 0.1 6.9 8 0 0 8 8 7 0 Tetratricopeptide repeat SNF2_N PF00176.18 EIW74988.1 - 1.5e-59 201.2 0.0 2.3e-59 200.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW74988.1 - 3e-14 52.6 0.1 8e-14 51.2 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EIW74988.1 - 4.2e-07 29.0 0.0 1.3e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD PF00628.24 EIW74988.1 - 0.012 15.2 21.9 0.017 14.7 7.0 2.9 2 1 1 3 3 3 0 PHD-finger Staph_haemo PF05480.6 EIW74988.1 - 0.076 12.7 0.1 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Staphylococcus haemolytic protein NOA36 PF06524.7 EIW74988.1 - 0.37 9.9 10.0 0.67 9.1 6.9 1.4 1 0 0 1 1 1 0 NOA36 protein Peptidase_A8 PF01252.13 EIW74989.1 - 0.012 15.1 6.7 0.021 14.4 4.5 1.5 1 1 0 1 1 1 0 Signal peptidase (SPase) II DUF2484 PF10658.4 EIW74989.1 - 0.66 10.1 5.9 0.96 9.6 2.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2484) Peptidase_A8 PF01252.13 EIW74990.1 - 8.4e-06 25.4 3.9 9.5e-06 25.2 1.8 1.6 1 1 0 1 1 1 1 Signal peptidase (SPase) II Mit_proteolip PF08039.6 EIW74991.1 - 0.017 15.1 0.6 0.19 11.7 0.2 2.3 2 0 0 2 2 2 0 Mitochondrial proteolipid SKG6 PF08693.5 EIW74993.1 - 0.0093 15.2 0.3 0.02 14.2 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain GATase PF00117.23 EIW74995.1 - 8.2e-07 28.6 0.1 4e-06 26.4 0.1 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I DUF1620 PF07774.8 EIW74996.1 - 9.1e-65 217.9 0.0 1.5e-64 217.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EIW74996.1 - 4.3e-20 72.1 4.5 2.4e-07 30.4 0.0 4.0 3 1 1 4 4 4 3 PQQ-like domain PQQ PF01011.16 EIW74996.1 - 1.9e-10 39.7 2.3 1.1 8.9 0.1 5.9 5 0 0 5 5 5 5 PQQ enzyme repeat DASH_Dam1 PF08653.5 EIW74997.1 - 0.3 10.8 2.1 0.95 9.2 1.4 1.9 1 0 0 1 1 1 0 DASH complex subunit Dam1 Fun_ATP-synt_8 PF05933.8 EIW74998.1 - 1.2 9.2 4.8 1.4 9.0 0.4 2.2 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) Abhydrolase_3 PF07859.8 EIW75000.1 - 2.7e-26 92.4 0.0 3.7e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIW75000.1 - 1.7e-07 30.2 0.0 2.7e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Neuralized PF07177.7 EIW75000.1 - 0.039 13.8 0.0 0.26 11.2 0.0 2.2 2 0 0 2 2 2 0 Neuralized DUF765 PF05570.6 EIW75000.1 - 0.041 13.8 5.2 1.1 9.2 1.5 2.9 2 0 0 2 2 2 0 Circovirus protein of unknown function (DUF765) DUF2930 PF11152.3 EIW75000.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2930) DUF4588 PF15251.1 EIW75003.1 - 0.0012 18.8 0.9 0.0012 18.8 0.6 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF4588) Paf1 PF03985.8 EIW75003.1 - 1.4 7.5 5.6 1.9 7.1 3.9 1.1 1 0 0 1 1 1 0 Paf1 Atrophin-1 PF03154.10 EIW75003.1 - 8 4.4 14.6 0.36 8.9 6.5 1.3 2 0 0 2 2 2 0 Atrophin-1 family Abhydrolase_6 PF12697.2 EIW75006.1 - 1.1e-20 74.5 1.5 1.9e-20 73.7 1.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW75006.1 - 1.1e-07 31.6 0.0 3.9e-07 29.8 0.0 1.9 3 0 0 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW75006.1 - 2.1e-06 27.5 0.0 4.5e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EIW75006.1 - 8.8e-05 22.0 0.1 0.002 17.5 0.0 2.1 2 0 0 2 2 2 1 Putative esterase PAF-AH_p_II PF03403.8 EIW75006.1 - 0.0068 14.7 0.0 0.013 13.8 0.0 1.3 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Peptidase_S9 PF00326.16 EIW75006.1 - 0.0068 15.6 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Lipase_3 PF01764.20 EIW75006.1 - 0.0089 15.6 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) TLD PF07534.11 EIW75007.1 - 3.9e-27 94.9 0.0 6.3e-27 94.2 0.0 1.3 1 0 0 1 1 1 1 TLD adh_short PF00106.20 EIW75008.1 - 7.1e-13 48.8 0.0 1.5e-12 47.7 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIW75008.1 - 0.00017 21.3 0.0 0.00034 20.3 0.0 1.5 2 0 0 2 2 2 1 KR domain Peptidase_C42 PF05533.7 EIW75008.1 - 0.094 12.5 0.0 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 Beet yellows virus-type papain-like endopeptidase C42 AF1Q PF15017.1 EIW75009.1 - 0.0058 16.5 2.5 0.0081 16.0 1.8 1.2 1 0 0 1 1 1 1 Drug resistance and apoptosis regulator tRNA_bind_2 PF13725.1 EIW75010.1 - 0.075 13.1 0.0 14 5.8 0.0 2.9 1 1 0 2 2 2 0 Possible tRNA binding domain Pex14_N PF04695.8 EIW75011.1 - 0.042 13.9 0.8 0.057 13.4 0.6 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mur_ligase PF01225.20 EIW75011.1 - 0.062 13.3 0.0 11 6.1 0.0 2.1 2 0 0 2 2 2 0 Mur ligase family, catalytic domain MIP-T3 PF10243.4 EIW75012.1 - 1.1 7.6 27.3 2 6.8 18.9 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 O-FucT PF10250.4 EIW75013.1 - 1.3e-06 27.7 0.0 2e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Na_Ca_ex PF01699.19 EIW75014.1 - 1.4e-26 92.8 21.4 8.3e-16 57.8 3.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF443 PF04276.7 EIW75014.1 - 3 7.2 7.5 0.13 11.6 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF443) tRNA_bind_2 PF13725.1 EIW75017.1 - 0.073 13.1 0.0 4 7.6 0.0 2.8 2 2 1 3 3 3 0 Possible tRNA binding domain adh_short PF00106.20 EIW75019.1 - 1.8e-15 57.2 0.0 3.1e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW75019.1 - 1.4e-05 24.8 0.0 2.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EIW75019.1 - 0.097 12.4 0.0 0.33 10.7 0.0 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_22 PF13383.1 EIW75021.1 - 5.7e-29 101.3 0.0 7.3e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 EIW75021.1 - 1.9e-06 27.9 0.0 3.8e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase FkbM domain MARVEL PF01284.18 EIW75022.1 - 7.4e-06 25.8 12.4 1.2e-05 25.1 8.6 1.4 1 0 0 1 1 1 1 Membrane-associating domain Herpes_UL45 PF05473.7 EIW75022.1 - 0.0012 18.3 0.8 0.0026 17.2 0.6 1.5 1 0 0 1 1 1 1 UL45 protein ABC_membrane PF00664.18 EIW75022.1 - 0.34 10.2 13.1 0.61 9.4 9.1 1.4 1 1 0 1 1 1 0 ABC transporter transmembrane region TctB PF07331.6 EIW75022.1 - 3.8 7.1 16.1 46 3.6 10.7 2.4 1 1 0 1 1 1 0 Tripartite tricarboxylate transporter TctB family F-box-like PF12937.2 EIW75024.1 - 0.0014 18.3 5.1 0.0017 18.0 1.9 2.5 3 0 0 3 3 3 1 F-box-like TRAP_alpha PF03896.11 EIW75027.1 - 0.12 11.4 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit STIL_N PF15253.1 EIW75027.1 - 0.2 10.3 0.2 0.3 9.7 0.2 1.2 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus DUF1180 PF06679.7 EIW75027.1 - 3.5 7.4 9.5 11 5.8 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) NACHT PF05729.7 EIW75028.1 - 3.8e-07 29.9 0.3 1.1e-06 28.4 0.2 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW75028.1 - 0.00023 21.2 0.1 0.00034 20.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW75028.1 - 0.011 15.8 0.0 0.031 14.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIW75028.1 - 0.02 15.2 0.0 0.033 14.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter NTPase_1 PF03266.10 EIW75028.1 - 0.048 13.3 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 NTPase PRK PF00485.13 EIW75028.1 - 0.051 13.1 0.1 0.083 12.4 0.1 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 EIW75028.1 - 0.07 13.3 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 EIW75028.1 - 0.1 11.9 0.0 0.15 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EIW75028.1 - 0.1 12.0 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 EIW75028.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PD40 PF07676.7 EIW75029.1 - 0.0019 17.8 0.3 2.6 7.8 0.1 3.8 4 0 0 4 4 4 2 WD40-like Beta Propeller Repeat adh_short PF00106.20 EIW75033.1 - 8.8e-18 64.7 0.0 1.1e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW75033.1 - 1.7e-06 27.8 0.0 1.5e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EIW75033.1 - 1.4e-05 24.3 0.0 2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EIW75033.1 - 0.004 17.1 0.0 0.0068 16.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW75033.1 - 0.0095 15.3 0.0 0.091 12.1 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EIW75033.1 - 0.013 15.5 0.0 0.053 13.6 0.0 2.0 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 EIW75033.1 - 0.026 14.3 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1858 PF08984.6 EIW75033.1 - 0.043 13.4 0.0 0.1 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) DUF1776 PF08643.5 EIW75033.1 - 0.077 12.1 0.0 0.11 11.5 0.0 1.3 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) FMN_dh PF01070.13 EIW75034.1 - 4.1e-113 377.8 0.2 5.1e-113 377.5 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.9 EIW75034.1 - 2.7e-07 29.9 0.6 0.017 14.2 0.1 2.9 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 EIW75034.1 - 3.8e-05 22.7 0.2 6.2e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EIW75034.1 - 0.00029 19.8 0.8 0.001 18.0 0.1 2.0 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EIW75034.1 - 0.012 14.7 2.3 0.047 12.8 1.6 1.8 2 0 0 2 2 2 0 Nitronate monooxygenase FMN_dh PF01070.13 EIW75035.1 - 4.8e-102 341.4 0.0 6.1e-102 341.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.9 EIW75035.1 - 0.0058 15.7 0.1 0.25 10.3 0.0 2.5 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG DUF3808 PF10300.4 EIW75037.1 - 2e-77 260.7 0.1 3.2e-77 260.0 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_2 PF07719.12 EIW75037.1 - 6e-07 28.9 6.8 0.83 9.7 0.1 5.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EIW75037.1 - 8.5e-06 25.3 5.3 0.09 12.4 2.3 4.1 3 1 0 3 3 3 1 TPR repeat TPR_12 PF13424.1 EIW75037.1 - 8.7e-06 25.5 4.2 0.069 13.0 0.1 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIW75037.1 - 0.00011 22.7 0.8 0.68 10.6 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIW75037.1 - 0.00068 20.0 2.0 3.5 8.5 0.0 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIW75037.1 - 0.0063 16.9 4.6 6.1 7.5 0.1 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIW75037.1 - 0.011 15.2 6.5 1.4 8.6 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EIW75037.1 - 0.012 15.9 3.1 3.2 8.1 0.1 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EIW75037.1 - 0.02 14.6 2.3 7.1 6.6 0.0 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.1 EIW75037.1 - 0.069 13.3 0.3 11 6.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EIW75037.1 - 0.62 10.6 8.8 2.4 8.8 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat GFA PF04828.9 EIW75038.1 - 2.3e-10 40.2 3.4 2.3e-10 40.2 2.4 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Gti1_Pac2 PF09729.4 EIW75039.1 - 9.7e-28 97.1 0.1 1.6e-25 89.9 0.0 2.0 1 1 0 1 1 1 1 Gti1/Pac2 family COX_ARM PF06481.9 EIW75039.1 - 0.02 14.5 0.0 0.037 13.6 0.0 1.4 1 0 0 1 1 1 0 COX Aromatic Rich Motif DUF4448 PF14610.1 EIW75039.1 - 0.14 11.6 0.0 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) F-box-like PF12937.2 EIW75043.1 - 1.2e-08 34.5 0.3 3.4e-08 33.0 0.2 1.9 1 0 0 1 1 1 1 F-box-like ApoO PF09769.4 EIW75044.1 - 1.5e-30 106.0 0.4 5.5e-30 104.1 0.0 2.0 2 1 0 2 2 2 1 Apolipoprotein O Apolipoprotein PF01442.13 EIW75044.1 - 0.023 14.2 3.2 0.42 10.1 2.6 2.4 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Ribosomal_L31 PF01197.13 EIW75045.1 - 2.7 8.0 5.9 13 5.8 2.1 2.6 2 1 0 2 2 2 0 Ribosomal protein L31 Pkinase_Tyr PF07714.12 EIW75046.1 - 2.7e-48 164.3 0.0 3.9e-48 163.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EIW75046.1 - 6.7e-42 143.4 0.0 3e-41 141.3 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EIW75046.1 - 0.00021 20.4 0.0 0.00046 19.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW75046.1 - 0.0038 16.9 1.9 0.04 13.6 0.0 2.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIW75046.1 - 0.013 14.8 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.1 EIW75046.1 - 0.027 13.4 0.0 0.045 12.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like 4HBT_2 PF13279.1 EIW75047.1 - 7.6e-08 32.8 0.0 1.3e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily Viral_coat PF00729.13 EIW75047.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Viral coat protein (S domain) TPR_17 PF13431.1 EIW75048.1 - 0.094 12.9 0.0 1.1 9.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3845 PF12956.2 EIW75048.1 - 0.13 11.6 0.0 0.16 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure TFIIA PF03153.8 EIW75052.1 - 0.0075 16.2 34.0 0.018 14.9 23.5 1.6 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CENP-T PF15511.1 EIW75052.1 - 0.93 8.6 24.4 1.7 7.7 16.9 1.5 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Astro_capsid PF03115.9 EIW75052.1 - 0.99 7.5 14.6 1.5 6.9 10.1 1.3 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Trypan_PARP PF05887.6 EIW75052.1 - 1.1 9.1 29.4 2.2 8.1 20.3 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CDC27 PF09507.5 EIW75052.1 - 3.8 6.6 31.9 7.2 5.7 22.1 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Glyco_hydro_3 PF00933.16 EIW75053.1 - 2e-77 260.1 0.1 2.9e-77 259.5 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIW75053.1 - 1.7e-59 201.0 3.5 1.4e-58 198.1 2.4 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIW75053.1 - 7.5e-19 67.4 0.1 1.7e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain VPS9 PF02204.13 EIW75054.1 - 2.7e-29 101.2 0.0 4.8e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EIW75054.1 - 6.1e-09 35.2 0.0 1.3e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 CUE domain DMA PF03474.9 EIW75054.1 - 0.00017 21.3 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 DMRTA motif BTB PF00651.26 EIW75055.1 - 5.5e-08 32.7 0.0 9.6e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain SUZ PF12752.2 EIW75056.1 - 1.5e-13 51.0 2.3 1.5e-13 51.0 1.6 3.3 3 1 1 4 4 4 1 SUZ domain SUZ-C PF12901.2 EIW75056.1 - 0.0013 18.2 2.2 0.0038 16.8 1.5 1.9 1 0 0 1 1 1 1 SUZ-C motif HMG_CoA_synt_C PF08540.5 EIW75058.1 - 9.3e-88 294.3 0.0 1.3e-87 293.8 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EIW75058.1 - 2.7e-85 284.2 0.1 3.7e-85 283.8 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal ACP_syn_III PF08545.5 EIW75058.1 - 0.0053 16.4 0.3 0.023 14.3 0.1 2.0 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 EIW75058.1 - 0.058 13.4 0.0 9.7 6.2 0.0 2.4 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal BCS1_N PF08740.6 EIW75059.1 - 4.5e-17 62.2 1.4 8.2e-17 61.4 1.0 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EIW75059.1 - 4.8e-14 52.6 0.0 5.6e-06 26.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIW75059.1 - 0.0026 17.7 0.1 0.01 15.8 0.0 2.1 3 0 0 3 3 3 1 AAA ATPase domain Viral_helicase1 PF01443.13 EIW75059.1 - 0.0033 16.9 0.0 0.0066 16.0 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 EIW75059.1 - 0.0082 15.1 0.0 0.016 14.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EIW75059.1 - 0.0083 16.0 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW75059.1 - 0.0097 16.7 0.0 0.026 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIW75059.1 - 0.02 13.9 0.0 0.042 12.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 EIW75059.1 - 0.04 13.6 0.0 0.099 12.4 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EIW75059.1 - 0.059 13.0 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain RuvB_N PF05496.7 EIW75059.1 - 0.082 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EIW75059.1 - 0.085 12.5 0.1 0.27 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.22 EIW75059.1 - 0.093 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter cobW PF02492.14 EIW75059.1 - 0.096 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EIW75059.1 - 0.12 12.5 0.0 0.29 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EIW75059.1 - 0.14 11.2 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_3 PF07726.6 EIW75059.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CAF-1_p150 PF11600.3 EIW75059.1 - 6.1 6.1 4.9 9.9 5.4 3.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal BTB PF00651.26 EIW75061.1 - 1.7e-09 37.6 0.0 3.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EIW75062.1 - 1.9e-08 34.2 0.0 4.5e-08 33.0 0.0 1.5 2 0 0 2 2 2 1 BTB/POZ domain AAA PF00004.24 EIW75063.1 - 4.6e-16 59.2 0.0 8.6e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 EIW75063.1 - 2.5e-09 37.0 0.0 3.8e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA_16 PF13191.1 EIW75063.1 - 0.00027 20.9 0.2 0.00091 19.2 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EIW75063.1 - 0.00033 21.4 0.0 0.00079 20.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW75063.1 - 0.0049 16.7 0.0 0.0095 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EIW75063.1 - 0.0052 16.4 0.0 0.015 14.9 0.0 1.9 1 1 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.7 EIW75063.1 - 0.0057 15.7 0.0 0.0092 15.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 EIW75063.1 - 0.0081 15.8 0.2 0.084 12.6 0.0 2.4 3 0 0 3 3 2 1 Part of AAA domain RuvB_N PF05496.7 EIW75063.1 - 0.019 14.0 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EIW75063.1 - 0.022 13.6 0.0 0.04 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TIP49 PF06068.8 EIW75063.1 - 0.025 13.3 0.0 0.038 12.7 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus DUF258 PF03193.11 EIW75063.1 - 0.031 13.4 0.0 0.057 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 EIW75063.1 - 0.055 13.2 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EIW75063.1 - 0.058 12.9 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EIW75063.1 - 0.072 13.3 0.0 0.17 12.1 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Viral_helicase1 PF01443.13 EIW75063.1 - 0.079 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EIW75063.1 - 0.089 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EIW75063.1 - 0.091 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Miro PF08477.8 EIW75063.1 - 0.11 12.9 0.1 0.31 11.5 0.0 1.8 2 0 0 2 2 1 0 Miro-like protein AAA_25 PF13481.1 EIW75063.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EIW75063.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 KaiC PAP2 PF01569.16 EIW75064.1 - 7.9e-13 48.2 3.9 1.2e-12 47.5 2.7 1.3 1 0 0 1 1 1 1 PAP2 superfamily BCS1_N PF08740.6 EIW75065.1 - 7.4e-26 90.9 0.3 1e-25 90.4 0.2 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EIW75065.1 - 2.8e-14 53.4 0.0 1.7e-13 50.9 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 EIW75065.1 - 0.0018 17.2 0.0 0.003 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EIW75065.1 - 0.0026 17.7 0.0 0.0057 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 EIW75065.1 - 0.0075 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 EIW75065.1 - 0.014 16.2 0.0 0.04 14.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EIW75065.1 - 0.02 13.9 0.0 0.033 13.2 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 EIW75065.1 - 0.031 13.8 0.1 0.074 12.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIW75065.1 - 0.098 12.9 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 EIW75065.1 - 0.12 11.8 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EIW75065.1 - 0.13 12.3 0.0 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pantoate_ligase PF02569.10 EIW75066.1 - 4e-76 255.4 0.0 1.1e-74 250.7 0.0 2.0 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase DUF1752 PF08550.5 EIW75068.1 - 4.3e-09 35.7 2.8 6.1e-09 35.3 1.9 1.3 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) BTB PF00651.26 EIW75069.1 - 0.0049 16.8 0.0 0.0063 16.4 0.0 1.1 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 EIW75069.1 - 0.12 12.5 0.1 0.16 12.1 0.1 1.2 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain BTB PF00651.26 EIW75070.1 - 2e-10 40.6 0.0 3.8e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BCS1_N PF08740.6 EIW75071.1 - 4.3e-25 88.4 0.0 6.7e-25 87.8 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EIW75071.1 - 7.2e-15 55.3 0.0 1.1e-06 28.9 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIW75071.1 - 0.0011 19.8 0.0 0.0032 18.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW75071.1 - 0.0034 17.4 0.1 0.012 15.5 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EIW75071.1 - 0.0055 16.5 0.0 0.019 14.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EIW75071.1 - 0.01 14.9 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF815 PF05673.8 EIW75071.1 - 0.025 13.5 0.0 0.046 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RuvB_N PF05496.7 EIW75071.1 - 0.026 13.5 0.0 0.043 12.8 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EIW75071.1 - 0.028 14.0 0.1 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_5 PF07728.9 EIW75071.1 - 0.051 13.2 0.0 0.095 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EIW75071.1 - 0.055 13.2 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 1 0 Part of AAA domain DUF258 PF03193.11 EIW75071.1 - 0.069 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TIP49 PF06068.8 EIW75071.1 - 0.069 11.8 0.0 0.14 10.7 0.0 1.4 2 0 0 2 2 2 0 TIP49 C-terminus AAA_29 PF13555.1 EIW75071.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EIW75071.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EIW75071.1 - 0.13 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase cobW PF02492.14 EIW75071.1 - 0.18 11.2 0.1 0.33 10.3 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Acetyltransf_1 PF00583.19 EIW75072.1 - 4.1e-08 33.1 0.0 5.4e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EIW75072.1 - 5.7e-06 26.4 0.0 8.2e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIW75072.1 - 5.3e-05 22.9 0.0 8.6e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EIW75072.1 - 0.00085 19.4 0.1 0.0016 18.5 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIW75072.1 - 0.095 12.5 0.1 0.21 11.4 0.1 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain BTB PF00651.26 EIW75073.1 - 0.0018 18.2 0.0 0.0039 17.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EIW75074.1 - 9.7e-10 38.4 0.0 1.8e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF1214 PF06742.6 EIW75075.1 - 0.039 14.4 0.2 0.061 13.7 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1214) F-box-like PF12937.2 EIW75076.1 - 0.07 12.8 6.6 0.093 12.4 0.1 3.6 3 0 0 3 3 3 0 F-box-like ESCRT-II PF05871.7 EIW75077.1 - 8.2e-36 122.9 0.0 1.2e-35 122.4 0.0 1.2 1 0 0 1 1 1 1 ESCRT-II complex subunit zf-RING_2 PF13639.1 EIW75078.1 - 4.2e-08 32.8 12.3 7.4e-08 32.1 8.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIW75078.1 - 8e-06 25.4 11.7 1.5e-05 24.5 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW75078.1 - 6e-05 22.9 12.4 0.00011 22.1 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW75078.1 - 7.9e-05 22.2 13.1 0.00013 21.4 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIW75078.1 - 0.00011 21.7 6.2 0.00011 21.7 4.3 2.1 1 1 1 2 2 2 1 RING-type zinc-finger AAA_13 PF13166.1 EIW75078.1 - 0.0044 15.5 7.1 0.0069 14.9 4.9 1.2 1 0 0 1 1 1 1 AAA domain zf-C3HC4_4 PF15227.1 EIW75078.1 - 0.0052 16.6 12.6 0.01 15.6 8.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EIW75078.1 - 0.0062 16.2 12.1 0.012 15.2 8.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EIW75078.1 - 0.053 13.1 9.3 0.11 12.0 6.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF3584 PF12128.3 EIW75078.1 - 0.059 10.6 24.4 0.089 10.1 16.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) zf-Apc11 PF12861.2 EIW75078.1 - 0.18 11.6 4.9 0.42 10.4 3.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Kinetocho_Slk19 PF12709.2 EIW75078.1 - 0.22 11.5 0.1 0.22 11.5 0.1 3.4 3 1 0 3 3 3 0 Central kinetochore-associated Tmpp129 PF10272.4 EIW75078.1 - 7.3 5.2 7.3 11 4.5 5.1 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor DUF2808 PF10989.3 EIW75079.1 - 0.029 13.9 0.0 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) NMO PF03060.10 EIW75080.1 - 3.9e-65 220.1 2.6 4.5e-65 219.9 1.8 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EIW75080.1 - 7.5e-05 21.7 1.1 0.0013 17.7 0.8 2.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EIW75080.1 - 0.0074 15.1 3.3 0.011 14.5 2.3 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase CALCOCO1 PF07888.6 EIW75081.1 - 0.098 10.9 31.5 0.59 8.3 15.7 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Filament PF00038.16 EIW75081.1 - 0.16 11.4 31.6 0.15 11.4 20.8 1.7 2 0 0 2 2 2 0 Intermediate filament protein DUF948 PF06103.6 EIW75081.1 - 0.41 10.5 4.7 0.58 10.0 0.5 3.0 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.6 EIW75081.1 - 1.5 7.3 25.8 0.32 9.6 9.1 2.4 1 1 2 3 3 3 0 Spc7 kinetochore protein DUF1789 PF08748.6 EIW75081.1 - 2.3 8.3 10.1 1.2 9.2 5.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1789) ERM PF00769.14 EIW75082.1 - 0.00076 19.0 7.4 0.0009 18.8 5.1 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Ax_dynein_light PF10211.4 EIW75082.1 - 0.0018 18.1 5.4 0.0027 17.5 3.7 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain L_lactis_ph-MCP PF06673.6 EIW75082.1 - 0.018 13.8 1.9 0.022 13.5 1.3 1.1 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein DUF4200 PF13863.1 EIW75082.1 - 0.021 14.7 6.3 0.033 14.1 4.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) TBPIP PF07106.8 EIW75082.1 - 0.028 13.9 1.6 0.037 13.5 1.1 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) bZIP_2 PF07716.10 EIW75082.1 - 0.04 13.7 1.5 0.04 13.7 1.0 2.7 3 0 0 3 3 3 0 Basic region leucine zipper Atg14 PF10186.4 EIW75082.1 - 0.044 12.7 3.6 0.068 12.1 2.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Med3 PF11593.3 EIW75082.1 - 0.051 12.8 3.9 0.077 12.2 2.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4472 PF14739.1 EIW75082.1 - 0.054 13.9 2.6 0.11 12.9 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4472) ATG16 PF08614.6 EIW75082.1 - 0.071 12.9 6.5 0.12 12.2 4.5 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Dor1 PF04124.7 EIW75082.1 - 0.077 11.4 2.1 0.089 11.2 1.0 1.3 1 1 0 1 1 1 0 Dor1-like family Cortex-I_coil PF09304.5 EIW75082.1 - 0.084 12.9 6.1 0.14 12.1 4.2 1.3 1 0 0 1 1 1 0 Cortexillin I, coiled coil DUF4407 PF14362.1 EIW75082.1 - 0.09 11.7 2.8 0.095 11.6 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_S49_N PF08496.5 EIW75082.1 - 0.1 12.4 3.1 0.13 12.0 2.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF972 PF06156.8 EIW75082.1 - 0.11 12.8 2.8 0.18 12.1 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Spc24 PF08286.6 EIW75082.1 - 0.15 11.8 0.8 0.22 11.2 0.5 1.4 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 APG6 PF04111.7 EIW75082.1 - 0.18 10.8 5.5 0.21 10.6 3.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EIW75082.1 - 0.31 10.6 3.3 0.44 10.1 2.3 1.3 1 0 0 1 1 1 0 IncA protein Mnd1 PF03962.10 EIW75082.1 - 0.37 10.4 7.8 0.52 9.9 5.4 1.2 1 0 0 1 1 1 0 Mnd1 family FUSC PF04632.7 EIW75082.1 - 0.54 8.6 2.7 0.62 8.4 1.9 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family TMF_DNA_bd PF12329.3 EIW75082.1 - 0.71 9.7 10.0 1.8 8.3 2.2 2.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding GAS PF13851.1 EIW75082.1 - 0.76 8.9 8.1 4.5 6.4 5.8 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIC PF04977.10 EIW75082.1 - 6.6 6.2 6.9 1.2 8.6 0.4 2.3 1 1 0 2 2 2 0 Septum formation initiator Striatin PF08232.7 EIW75082.1 - 9.3 6.5 10.3 19 5.5 7.2 1.6 1 1 0 1 1 1 0 Striatin family Ribosomal_60s PF00428.14 EIW75082.1 - 9.7 6.6 14.9 80 3.7 10.3 2.0 1 1 0 1 1 1 0 60s Acidic ribosomal protein BTB PF00651.26 EIW75083.1 - 2.2e-09 37.2 0.0 6.6e-09 35.7 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Hydrophobin PF01185.13 EIW75084.1 - 4.4e-17 62.2 8.0 5.3e-17 62.0 5.6 1.1 1 0 0 1 1 1 1 Fungal hydrophobin BTB PF00651.26 EIW75085.1 - 5.4e-06 26.3 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain CDP-OH_P_transf PF01066.16 EIW75086.1 - 8.1e-19 67.8 3.9 1.9e-18 66.6 2.7 1.6 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase Lebercilin PF15619.1 EIW75087.1 - 0.00081 18.8 9.7 0.00081 18.8 6.8 7.6 3 3 2 7 7 7 2 Ciliary protein causing Leber congenital amaurosis disease WEMBL PF05701.6 EIW75087.1 - 0.0013 17.2 32.9 0.0013 17.2 22.8 5.1 3 1 2 5 5 5 3 Weak chloroplast movement under blue light SlyX PF04102.7 EIW75087.1 - 0.0029 17.9 2.2 0.0029 17.9 1.5 11.0 10 3 3 13 13 13 2 SlyX Reo_sigmaC PF04582.7 EIW75087.1 - 0.005 16.0 2.1 0.005 16.0 1.5 4.4 3 1 2 5 5 5 2 Reovirus sigma C capsid protein AAA_13 PF13166.1 EIW75087.1 - 0.0051 15.3 57.3 0.0072 14.8 9.8 4.5 2 2 2 4 4 4 3 AAA domain FliJ PF02050.11 EIW75087.1 - 0.0063 16.5 12.7 0.0063 16.5 8.8 8.8 4 4 3 7 7 7 3 Flagellar FliJ protein TMF_DNA_bd PF12329.3 EIW75087.1 - 0.0074 16.0 1.8 0.0074 16.0 1.3 11.7 10 3 1 11 11 11 2 TATA element modulatory factor 1 DNA binding Methyltransf_11 PF08241.7 EIW75090.1 - 5e-06 26.9 0.0 9.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW75090.1 - 1.1e-05 25.0 0.0 3.1e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW75090.1 - 0.00014 22.1 0.0 0.00031 21.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW75090.1 - 0.00067 19.4 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW75090.1 - 0.018 15.5 0.0 0.038 14.4 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EIW75090.1 - 0.026 13.6 0.0 0.46 9.5 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EIW75090.1 - 0.043 13.7 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 EIW75090.1 - 0.075 12.0 0.0 0.15 11.0 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_26 PF13659.1 EIW75090.1 - 0.095 12.7 0.0 0.4 10.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Rxt3 PF08642.5 EIW75092.1 - 0.0003 21.0 0.0 0.0003 21.0 0.0 3.6 3 0 0 3 3 3 1 Histone deacetylation protein Rxt3 SAPS PF04499.10 EIW75092.1 - 8.9 4.8 11.5 6.9e+02 -1.5 8.0 2.5 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein DNA_pol_delta_4 PF04081.8 EIW75094.1 - 4.3e-26 91.6 1.2 2.7e-25 89.0 0.3 2.1 2 0 0 2 2 2 1 DNA polymerase delta, subunit 4 BNIP2 PF12496.3 EIW75094.1 - 0.018 15.2 1.0 0.027 14.6 0.7 1.3 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 DUF566 PF04484.7 EIW75094.1 - 3.6 7.0 10.1 4.5 6.6 7.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) Ribosomal_60s PF00428.14 EIW75094.1 - 4.5 7.7 12.2 2.6 8.5 4.8 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein FAD_binding_3 PF01494.14 EIW75095.1 - 2.1e-80 270.4 0.0 2.7e-80 270.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EIW75095.1 - 1.9e-30 105.6 0.0 2.9e-30 105.0 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 EIW75095.1 - 3.6e-06 27.3 0.3 0.0057 17.0 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW75095.1 - 5.6e-06 25.0 0.4 9.1e-06 24.3 0.3 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EIW75095.1 - 2.7e-05 23.4 0.1 4.5e-05 22.6 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EIW75095.1 - 8.5e-05 22.5 0.1 0.00024 21.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIW75095.1 - 8.9e-05 21.5 0.1 0.00015 20.7 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIW75095.1 - 0.00031 20.6 0.3 0.00071 19.5 0.2 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW75095.1 - 0.00034 19.5 1.5 0.00052 18.9 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EIW75095.1 - 0.0011 18.0 0.7 0.002 17.1 0.5 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EIW75095.1 - 0.0019 16.9 0.1 0.0026 16.4 0.0 1.1 1 0 0 1 1 1 1 Tryptophan halogenase NAD_binding_9 PF13454.1 EIW75095.1 - 0.0035 17.1 0.1 0.0063 16.2 0.1 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EIW75095.1 - 0.016 15.3 0.2 0.039 14.0 0.2 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EIW75095.1 - 0.019 14.6 0.2 0.033 13.8 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EIW75095.1 - 0.053 12.3 1.0 0.092 11.5 0.7 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.11 EIW75095.1 - 0.071 12.5 0.2 0.14 11.5 0.1 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.16 EIW75095.1 - 0.075 12.6 0.2 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EIW75095.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.13 EIW75095.1 - 0.14 12.1 0.1 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.14 EIW75097.1 - 1.4e-85 287.4 0.0 5.1e-84 282.3 0.0 2.7 2 0 0 2 2 2 1 FAD binding domain Phe_hydrox_dim PF07976.7 EIW75097.1 - 4.7e-27 94.6 0.0 1.1e-26 93.4 0.0 1.7 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain ADIP PF11559.3 EIW75097.1 - 2.5e-10 40.4 15.5 2.5e-10 40.4 10.7 2.8 3 0 0 3 3 1 1 Afadin- and alpha -actinin-Binding HI0933_like PF03486.9 EIW75097.1 - 1.5e-06 26.9 0.8 1.5e-06 26.9 0.5 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EIW75097.1 - 2.9e-06 26.4 2.3 2.9e-06 26.4 1.6 2.6 3 1 1 4 4 4 1 FAD binding domain Pyr_redox_2 PF07992.9 EIW75097.1 - 6.4e-05 22.9 0.7 0.00024 21.0 0.5 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW75097.1 - 7.4e-05 21.8 0.2 7.4e-05 21.8 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW75097.1 - 9.6e-05 22.3 0.1 9.6e-05 22.3 0.1 2.4 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIW75097.1 - 0.00047 19.3 0.2 0.0011 18.1 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EIW75097.1 - 0.00058 20.2 0.1 0.0028 18.0 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIW75097.1 - 0.00076 18.5 1.1 0.0014 17.6 0.8 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 EIW75097.1 - 0.0023 17.3 0.1 0.014 14.7 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EIW75097.1 - 0.0044 16.6 0.2 0.0044 16.6 0.2 2.5 3 0 0 3 3 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EIW75097.1 - 0.0055 16.7 0.2 0.017 15.1 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.1 EIW75097.1 - 0.0097 16.2 0.0 0.09 13.0 0.0 2.7 2 0 0 2 2 2 1 XdhC Rossmann domain AlaDh_PNT_C PF01262.16 EIW75097.1 - 0.012 15.1 0.4 0.061 12.8 0.2 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 EIW75097.1 - 0.015 14.7 0.1 0.041 13.3 0.1 1.8 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.1 EIW75097.1 - 0.017 14.8 0.1 0.044 13.5 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding CPSase_L_chain PF00289.17 EIW75097.1 - 0.028 14.5 0.0 2.3 8.3 0.0 2.9 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain TrkA_N PF02254.13 EIW75097.1 - 0.044 13.7 0.2 0.14 12.1 0.0 2.0 2 0 0 2 2 1 0 TrkA-N domain DUF2199 PF09965.4 EIW75097.1 - 0.068 13.0 0.5 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2199) vATP-synt_E PF01991.13 EIW75097.1 - 0.072 12.3 8.7 0.21 10.8 6.1 1.7 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit NAD_binding_7 PF13241.1 EIW75097.1 - 0.095 12.9 0.0 0.28 11.4 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Filament PF00038.16 EIW75097.1 - 0.16 11.4 19.9 0.88 8.9 5.1 2.3 2 0 0 2 2 2 0 Intermediate filament protein ThiF PF00899.16 EIW75097.1 - 0.16 11.7 0.1 0.4 10.5 0.1 1.6 1 0 0 1 1 1 0 ThiF family GIDA PF01134.17 EIW75097.1 - 0.85 8.4 9.8 0.01 14.7 1.2 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A AIP3 PF03915.8 EIW75097.1 - 1.3 7.8 12.8 0.73 8.6 3.9 2.1 2 0 0 2 2 2 0 Actin interacting protein 3 Ran_BP1 PF00638.13 EIW75098.1 - 2.7e-19 69.3 0.0 4.7e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain HATPase_c PF02518.21 EIW75099.1 - 8.5e-23 80.2 4.6 7.3e-22 77.1 2.2 2.7 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EIW75099.1 - 5.4e-17 61.8 1.0 7.6e-10 38.7 0.0 3.0 3 0 0 3 3 3 2 Response regulator receiver domain HisKA PF00512.20 EIW75099.1 - 2.5e-06 27.3 0.4 1.4e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.1 EIW75099.1 - 0.081 12.5 0.1 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase zf-HC5HC2H_2 PF13832.1 EIW75100.1 - 3.3e-20 72.1 25.4 2e-18 66.4 0.5 4.5 3 1 1 4 4 4 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EIW75100.1 - 2.2e-13 50.1 2.0 2.2e-13 50.1 1.4 4.5 3 1 1 4 4 4 2 PHD-like zinc-binding domain PHD PF00628.24 EIW75100.1 - 1.5e-12 46.9 56.8 2.5e-08 33.4 5.8 6.0 6 1 1 7 7 7 3 PHD-finger BAH PF01426.13 EIW75100.1 - 4.4e-07 29.6 0.0 8.4e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 BAH domain GATA PF00320.22 EIW75100.1 - 1.7e-05 24.0 2.5 1.7e-05 24.0 1.7 3.2 3 0 0 3 3 3 1 GATA zinc finger PHD_2 PF13831.1 EIW75100.1 - 0.00018 20.7 39.0 0.0013 18.0 4.6 6.5 7 0 0 7 7 7 3 PHD-finger ELM2 PF01448.19 EIW75100.1 - 0.029 15.0 0.0 0.12 13.0 0.0 2.1 1 0 0 1 1 1 0 ELM2 domain AT_hook PF02178.14 EIW75100.1 - 3.4 7.6 9.2 0.59 9.9 3.4 2.2 2 0 0 2 2 2 0 AT hook motif OTT_1508_deam PF14441.1 EIW75101.1 - 0.0013 18.5 0.0 0.0036 17.0 0.0 2.0 1 1 0 1 1 1 1 OTT_1508-like deaminase KBP_C PF12309.3 EIW75102.1 - 0.017 14.1 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 KIF-1 binding protein C terminal Glycos_transf_2 PF00535.21 EIW75103.1 - 5.2e-23 81.5 0.0 7.5e-23 81.0 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EIW75103.1 - 1e-12 48.3 0.0 9.3e-12 45.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 EIW75103.1 - 0.015 15.6 0.0 0.037 14.3 0.0 1.7 2 0 0 2 2 2 0 Glycosyl transferase family 2 Ribosomal_L5_C PF00673.16 EIW75104.1 - 7.8e-22 76.8 0.0 1.2e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EIW75104.1 - 2e-20 72.3 0.2 4.6e-20 71.1 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L5 WD40 PF00400.27 EIW75106.1 - 1.3e-45 151.6 25.0 5.3e-12 45.1 0.4 8.5 8 1 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EIW75106.1 - 3e-05 22.3 1.3 0.45 8.5 0.1 3.8 2 1 2 4 4 4 3 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EIW75106.1 - 0.1 12.9 13.5 12 6.3 0.0 5.8 7 1 0 7 7 7 0 PQQ-like domain TPR_11 PF13414.1 EIW75107.1 - 2.5e-37 126.3 27.3 1.7e-15 56.3 2.7 5.4 4 1 2 6 6 6 6 TPR repeat TPR_1 PF00515.23 EIW75107.1 - 3.9e-28 95.8 10.2 0.00051 19.5 0.1 7.8 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.12 EIW75107.1 - 2e-22 77.2 30.6 0.00079 19.1 0.1 9.2 10 0 0 10 10 9 6 Tetratricopeptide repeat DnaJ PF00226.26 EIW75107.1 - 2.8e-22 78.2 0.2 7.8e-22 76.7 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_12 PF13424.1 EIW75107.1 - 3.4e-13 49.3 25.4 8.1e-07 28.8 0.3 6.0 4 2 3 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.1 EIW75107.1 - 1.8e-11 43.5 54.2 0.00015 22.1 3.1 9.1 4 4 5 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.1 EIW75107.1 - 5.5e-11 42.6 27.2 0.00033 20.9 0.2 6.2 4 2 3 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIW75107.1 - 9.9e-11 42.0 58.8 6.8e-06 26.6 1.7 7.4 3 2 2 7 7 7 5 Tetratricopeptide repeat TPR_17 PF13431.1 EIW75107.1 - 2.4e-07 30.4 8.2 0.35 11.1 0.2 6.5 8 0 0 8 8 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EIW75107.1 - 8.2e-07 29.0 3.3 0.00037 20.5 0.3 3.6 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EIW75107.1 - 2.3e-06 26.9 6.1 2.6 8.0 0.0 7.4 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_9 PF13371.1 EIW75107.1 - 3.6e-06 26.7 32.2 0.027 14.3 2.2 5.1 4 1 2 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 EIW75107.1 - 0.049 13.4 12.6 19 5.3 0.0 5.9 5 0 0 5 5 5 0 Tetratricopeptide repeat Coatomer_E PF04733.9 EIW75107.1 - 0.11 11.6 2.7 12 5.0 0.0 3.7 3 1 1 4 4 4 0 Coatomer epsilon subunit Fis1_TPR_C PF14853.1 EIW75107.1 - 0.25 11.2 0.1 0.25 11.2 0.1 4.0 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 EIW75107.1 - 1.1 9.2 9.4 4.6 7.1 0.0 4.1 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 EIW75107.1 - 1.5 9.4 0.0 1.5 9.4 0.0 6.7 9 1 1 10 10 6 0 Tetratricopeptide repeat OTT_1508_deam PF14441.1 EIW75108.1 - 1.7e-13 50.6 0.3 4.5e-13 49.2 0.0 1.9 3 0 0 3 3 3 1 OTT_1508-like deaminase DUF3254 PF11630.3 EIW75109.1 - 0.11 12.4 0.0 5.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3254) OTT_1508_deam PF14441.1 EIW75110.1 - 3.8e-15 55.9 0.0 6.3e-15 55.2 0.0 1.3 1 1 0 1 1 1 1 OTT_1508-like deaminase DUF3430 PF11912.3 EIW75112.1 - 0.0073 16.1 0.1 0.0078 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Kp4 PF09044.5 EIW75112.1 - 0.039 13.7 1.3 0.048 13.4 0.9 1.3 1 1 0 1 1 1 0 Kp4 CMD PF02627.15 EIW75113.1 - 2.1e-05 24.2 0.0 0.00018 21.2 0.0 2.3 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family SH3_1 PF00018.23 EIW75114.1 - 1.9e-30 103.9 1.8 9.5e-15 53.7 0.1 2.3 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EIW75114.1 - 4.2e-29 99.8 0.4 3.4e-15 55.3 0.1 2.3 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EIW75114.1 - 9e-19 66.7 0.1 1.5e-10 40.3 0.0 3.0 3 0 0 3 3 3 2 Variant SH3 domain Cofilin_ADF PF00241.15 EIW75114.1 - 1.3e-15 57.3 0.0 2.1e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein RNase_H2_suC PF08615.6 EIW75115.1 - 2.3e-28 98.7 0.0 3.4e-28 98.1 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) GPI-anchored PF10342.4 EIW75116.1 - 5.5e-09 36.3 1.3 5.5e-09 36.3 0.9 2.5 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family AKAP2_C PF15304.1 EIW75116.1 - 0.53 9.8 4.1 0.72 9.4 2.9 1.2 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus Peptidase_S64 PF08192.6 EIW75117.1 - 0.006 14.9 0.0 0.24 9.6 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S64 Peptidase_S3 PF00944.14 EIW75117.1 - 0.026 13.9 0.1 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 Alphavirus core protein DUF4611 PF15387.1 EIW75117.1 - 0.22 11.6 3.5 0.32 11.1 0.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 EIW75117.1 - 2.1 7.8 6.4 3.8 7.0 4.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin COesterase PF00135.23 EIW75118.1 - 3.4e-58 197.6 0.0 4.8e-58 197.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW75118.1 - 2.1e-06 27.4 0.1 8.8e-06 25.4 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Polysacc_deac_1 PF01522.16 EIW75119.1 - 1e-17 63.8 0.0 2.2e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EIW75119.1 - 0.0011 18.4 0.1 0.0022 17.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) AA_permease_2 PF13520.1 EIW75120.1 - 2.9e-50 171.0 51.3 3.6e-50 170.7 35.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIW75120.1 - 1.4e-14 53.3 44.7 2.1e-14 52.7 31.0 1.2 1 0 0 1 1 1 1 Amino acid permease DUF3341 PF11821.3 EIW75120.1 - 0.011 15.2 1.7 0.045 13.2 1.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) Arginase PF00491.16 EIW75121.1 - 4.6e-85 285.2 0.0 5.8e-85 284.9 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EIW75121.1 - 0.091 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain MatE PF01554.13 EIW75122.1 - 1.2e-45 155.0 28.3 8.2e-25 87.3 5.6 2.6 2 1 0 2 2 2 2 MatE Thioredoxin PF00085.15 EIW75123.1 - 5.8e-22 77.3 0.0 4.8e-21 74.3 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_2 PF13098.1 EIW75123.1 - 0.0001 22.4 0.3 0.00081 19.5 0.0 2.3 2 1 0 2 2 2 1 Thioredoxin-like domain Redoxin PF08534.5 EIW75123.1 - 0.00037 20.0 0.1 0.0082 15.7 0.0 2.4 2 1 0 2 2 2 1 Redoxin Thioredoxin_8 PF13905.1 EIW75123.1 - 0.00074 19.5 0.0 0.0045 17.0 0.0 2.2 2 1 1 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.16 EIW75123.1 - 0.003 17.2 0.2 0.021 14.5 0.0 2.3 2 1 0 2 2 2 1 AhpC/TSA family Thioredoxin_7 PF13899.1 EIW75123.1 - 0.0044 17.0 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EIW75123.1 - 0.041 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin STT3 PF02516.9 EIW75124.1 - 1.5e-130 436.3 34.4 5.5e-129 431.2 23.8 2.2 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.1 EIW75124.1 - 4.7e-05 23.3 10.5 4.7e-05 23.3 7.3 3.4 5 0 0 5 5 5 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Ran_BP1 PF00638.13 EIW75125.1 - 6.4e-08 32.6 0.0 1.2e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain Abhydrolase_3 PF07859.8 EIW75126.1 - 1.4e-25 90.1 0.0 1.9e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIW75126.1 - 1.5e-11 43.5 0.0 3.7e-11 42.2 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Thioesterase PF00975.15 EIW75126.1 - 0.0029 17.8 0.0 0.0049 17.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 EIW75126.1 - 0.013 15.2 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family HAD_2 PF13419.1 EIW75126.1 - 0.016 15.4 0.0 0.045 13.9 0.0 1.7 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase BAAT_C PF08840.6 EIW75126.1 - 0.028 14.1 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal EPL1 PF10513.4 EIW75127.1 - 6.5e-24 84.9 3.6 6.5e-24 84.9 2.5 3.3 3 1 0 3 3 2 1 Enhancer of polycomb-like Bromodomain PF00439.20 EIW75127.1 - 1e-17 63.8 0.1 2.4e-17 62.6 0.1 1.7 1 0 0 1 1 1 1 Bromodomain zf-HC5HC2H_2 PF13832.1 EIW75127.1 - 8.2e-15 54.7 0.5 6.7e-13 48.5 0.0 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain PHD_2 PF13831.1 EIW75127.1 - 1.3e-14 53.2 3.4 2.3e-14 52.3 2.3 1.4 1 0 0 1 1 1 1 PHD-finger PWWP PF00855.12 EIW75127.1 - 2.7e-12 46.7 0.2 7.4e-12 45.3 0.1 1.8 1 0 0 1 1 1 1 PWWP domain PHD PF00628.24 EIW75127.1 - 5.5e-10 38.7 5.9 1.3e-09 37.6 4.1 1.7 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.1 EIW75127.1 - 0.002 17.4 1.0 0.004 16.4 0.7 1.5 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 EIW75127.1 - 0.0024 17.5 0.3 0.0054 16.4 0.2 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EIW75127.1 - 0.089 12.5 1.5 0.18 11.5 1.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.1 EIW75127.1 - 0.12 12.5 3.8 1 9.5 0.0 2.8 3 0 0 3 3 3 0 PHD-like zinc-binding domain zf-RanBP PF00641.13 EIW75127.1 - 0.47 9.6 2.3 0.63 9.1 0.2 2.1 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others FYVE_2 PF02318.11 EIW75127.1 - 2.6 7.9 6.9 0.12 12.2 0.2 2.2 2 0 0 2 2 2 0 FYVE-type zinc finger zf-MYND PF01753.13 EIW75128.1 - 2.8e-08 33.4 10.0 6e-08 32.4 6.9 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EIW75128.1 - 0.42 10.4 5.5 0.9 9.4 3.8 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 WLM PF08325.5 EIW75129.1 - 1.2e-39 136.1 0.0 2e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 WLM domain ubiquitin PF00240.18 EIW75129.1 - 1.9e-10 39.9 0.0 3.3e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EIW75129.1 - 0.00014 21.9 0.0 0.00028 21.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.3 EIW75129.1 - 0.00033 20.2 0.0 0.0007 19.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF45 PF01863.12 EIW75129.1 - 0.013 15.3 2.2 0.2 11.4 0.3 2.9 2 2 1 3 3 3 0 Protein of unknown function DUF45 SprT-like PF10263.4 EIW75129.1 - 0.02 14.5 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 SprT-like family Peptidase_MA_2 PF13485.1 EIW75129.1 - 0.022 14.7 0.4 0.041 13.9 0.3 1.5 1 1 0 1 1 1 0 Peptidase MA superfamily LRV PF01816.12 EIW75129.1 - 0.88 9.9 5.8 3.7 7.9 0.7 3.2 2 0 0 2 2 2 0 Leucine rich repeat variant Mito_carr PF00153.22 EIW75130.1 - 4.2e-58 193.0 0.2 2.1e-20 72.2 0.0 3.9 3 1 0 3 3 3 3 Mitochondrial carrier protein TPR_MLP1_2 PF07926.7 EIW75132.1 - 0.017 14.8 1.8 0.026 14.2 1.3 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Laminin_II PF06009.7 EIW75132.1 - 0.02 14.6 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 Laminin Domain II DUF3498 PF12004.3 EIW75132.1 - 0.024 13.8 0.5 0.031 13.4 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) ALIX_LYPXL_bnd PF13949.1 EIW75132.1 - 0.031 13.2 0.0 0.038 12.9 0.0 1.0 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV Ino80_Iec3 PF14612.1 EIW75132.1 - 0.052 13.6 2.0 0.069 13.2 1.4 1.1 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling HSF_DNA-bind PF00447.12 EIW75133.1 - 2e-32 111.4 1.4 2.2e-32 111.3 1.0 1.0 1 0 0 1 1 1 1 HSF-type DNA-binding 2OG-FeII_Oxy_3 PF13640.1 EIW75139.1 - 1.1e-05 25.9 0.0 3.4e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIW75139.1 - 0.00045 20.4 0.0 0.00097 19.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LRR_4 PF12799.2 EIW75140.1 - 1.4 8.6 6.2 8.7 6.0 0.0 4.1 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) DDE_1 PF03184.14 EIW75141.1 - 4.4e-05 22.7 0.0 4.9e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIW75141.1 - 0.0056 16.4 0.0 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease TraC_F_IV PF11130.3 EIW75143.1 - 0.052 12.9 0.1 1.5 8.2 0.0 2.1 2 0 0 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer Plexin_cytopl PF08337.7 EIW75143.1 - 0.2 9.9 0.0 0.29 9.4 0.0 1.1 1 0 0 1 1 1 0 Plexin cytoplasmic RasGAP domain DPPIV_N PF00930.16 EIW75144.1 - 1.3e-91 306.8 0.1 1.6e-91 306.5 0.1 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EIW75144.1 - 3.3e-42 144.1 3.0 5.8e-42 143.3 2.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIW75144.1 - 1.6e-06 27.9 0.1 4.2e-06 26.5 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW75144.1 - 1.8e-05 24.7 0.3 4.3e-05 23.5 0.2 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EIW75144.1 - 0.0015 17.9 3.9 0.0034 16.8 2.0 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.7 EIW75144.1 - 0.033 12.6 0.0 0.08 11.4 0.0 1.6 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) DUF2048 PF09752.4 EIW75144.1 - 0.14 11.0 0.1 0.27 10.0 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) EF-hand_8 PF13833.1 EIW75146.1 - 0.006 16.1 0.0 0.016 14.8 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair LisH PF08513.6 EIW75149.1 - 0.00031 20.4 0.0 0.00046 19.8 0.0 1.3 1 0 0 1 1 1 1 LisH START PF01852.14 EIW75150.1 - 1.5e-20 73.4 0.2 1e-10 41.2 0.0 3.8 3 0 0 3 3 3 3 START domain Serglycin PF04360.7 EIW75150.1 - 0.0062 16.2 0.2 0.027 14.2 0.2 2.1 1 0 0 1 1 1 1 Serglycin DUF3148 PF11347.3 EIW75150.1 - 0.16 11.5 0.1 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3148) Phos_pyr_kin PF08543.7 EIW75151.1 - 1.2e-11 44.2 0.0 1.7e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EIW75151.1 - 4.9e-07 29.1 1.2 3.5e-05 23.0 0.1 2.6 2 1 0 2 2 2 1 pfkB family carbohydrate kinase NUC153 PF08159.7 EIW75153.1 - 5.9e-13 48.1 13.0 1.8e-12 46.6 0.2 3.7 3 0 0 3 3 3 3 NUC153 domain Mt_ATP-synt_B PF05405.9 EIW75154.1 - 9.9e-45 151.9 5.1 1.2e-44 151.6 3.5 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) DUF1539 PF07560.6 EIW75154.1 - 0.027 14.3 0.3 0.047 13.5 0.2 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1539) Viral_Hsp90 PF03225.9 EIW75154.1 - 0.028 12.6 0.3 0.039 12.2 0.2 1.1 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue DUF1931 PF09123.6 EIW75154.1 - 0.044 13.7 2.2 0.29 11.0 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1931) Dynamin_M PF01031.15 EIW75155.1 - 1e-109 365.9 0.0 1.7e-109 365.1 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EIW75155.1 - 9.9e-55 184.9 0.0 1.8e-54 184.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EIW75155.1 - 5.4e-29 99.9 1.2 2.7e-28 97.6 0.3 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EIW75155.1 - 0.0079 16.1 0.0 0.035 14.0 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EIW75155.1 - 0.011 15.7 0.0 0.03 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Miro PF08477.8 EIW75155.1 - 0.043 14.3 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AIG1 PF04548.11 EIW75155.1 - 0.13 11.2 0.1 12 4.9 0.0 2.4 2 0 0 2 2 2 0 AIG1 family BCS1_N PF08740.6 EIW75156.1 - 4.7e-28 98.0 1.0 4.7e-28 98.0 0.7 2.2 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 EIW75156.1 - 6.3e-15 55.5 0.0 1.2e-13 51.3 0.0 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIW75156.1 - 0.0019 18.2 0.1 0.0019 18.2 0.1 2.7 2 2 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EIW75156.1 - 0.0021 17.9 0.0 0.0021 17.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain Viral_helicase1 PF01443.13 EIW75156.1 - 0.0038 16.7 0.0 0.0093 15.5 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_17 PF13207.1 EIW75156.1 - 0.0086 16.8 0.0 0.0086 16.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.7 EIW75156.1 - 0.021 13.8 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EIW75156.1 - 0.024 14.2 4.8 2.6 7.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF572 PF04502.8 EIW75156.1 - 0.087 12.0 18.2 0.18 11.0 12.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF572) AAA_19 PF13245.1 EIW75156.1 - 0.11 12.2 0.0 0.33 10.7 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EIW75156.1 - 0.12 12.0 0.1 0.34 10.5 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 EIW75156.1 - 0.13 12.3 0.0 0.33 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EIW75156.1 - 0.14 11.7 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EIW75156.1 - 0.31 11.3 0.1 0.31 11.3 0.1 2.9 3 1 0 3 3 2 0 AAA domain DUF4557 PF15101.1 EIW75156.1 - 4 7.2 6.7 5.1 6.8 4.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4557) SYS1 PF09801.4 EIW75157.1 - 1.3e-25 90.0 8.8 1.7e-24 86.4 6.1 2.0 1 1 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Oxidored_FMN PF00724.15 EIW75158.1 - 2e-96 322.9 0.0 2.5e-96 322.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 EIW75159.1 - 1.3e-97 326.8 0.0 1.5e-97 326.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 EIW75160.1 - 1.2e-85 287.4 0.0 1.5e-85 287.2 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family FYDLN_acid PF09538.5 EIW75163.1 - 0.54 10.8 7.0 1.5 9.4 4.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DUF1670 PF07900.6 EIW75167.1 - 0.02 14.1 0.1 0.043 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1670) DUF4248 PF14053.1 EIW75167.1 - 0.041 13.4 0.8 1.2 8.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) Pox_TAA1 PF03295.9 EIW75167.1 - 0.053 13.1 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Poxvirus trans-activator protein A1 C-terminal BetaGal_dom4_5 PF13364.1 EIW75169.1 - 0.089 13.0 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Actin PF00022.14 EIW75177.1 - 5.1e-122 407.0 0.0 6.1e-122 406.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EIW75177.1 - 0.0057 15.3 0.0 0.02 13.5 0.0 1.8 1 1 0 1 1 1 1 MreB/Mbl protein Lipase_3 PF01764.20 EIW75178.1 - 1e-20 73.7 0.0 1.4e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EIW75178.1 - 0.0082 16.0 0.1 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family SFTA2 PF15210.1 EIW75178.1 - 0.02 14.4 0.2 0.049 13.2 0.1 1.6 1 0 0 1 1 1 0 Surfactant-associated protein 2 Abhydrolase_5 PF12695.2 EIW75178.1 - 0.081 12.6 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Metallophos PF00149.23 EIW75179.1 - 6.1e-10 38.8 3.1 4.5e-09 35.9 2.1 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIW75179.1 - 0.00017 21.4 0.0 0.00083 19.2 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DBD_Tnp_Mut PF03108.10 EIW75180.1 - 0.083 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 MuDR family transposase Membr_traf_MHD PF10540.4 EIW75180.1 - 0.095 12.4 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Munc13 (mammalian uncoordinated) homology domain F-box-like PF12937.2 EIW75181.1 - 2.1e-06 27.3 0.7 2.1e-06 27.3 0.5 2.5 2 0 0 2 2 2 1 F-box-like Romo1 PF10247.4 EIW75182.1 - 0.015 15.4 0.2 0.033 14.3 0.1 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 SurE PF01975.12 EIW75182.1 - 0.04 13.2 0.1 0.074 12.3 0.1 1.4 1 0 0 1 1 1 0 Survival protein SurE Syndecan PF01034.15 EIW75182.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain DUF2613 PF11021.3 EIW75182.1 - 4.6 7.0 10.7 21 4.9 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2613) UBX PF00789.15 EIW75184.1 - 3.3e-11 43.0 0.8 6.6e-11 42.1 0.1 1.8 2 0 0 2 2 2 1 UBX domain UBA PF00627.26 EIW75184.1 - 0.042 13.7 0.3 0.33 10.8 0.0 2.7 2 0 0 2 2 2 0 UBA/TS-N domain zf-C2H2_2 PF12756.2 EIW75184.1 - 0.073 13.1 1.9 0.16 12.1 0.2 2.1 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) ADH_zinc_N_2 PF13602.1 EIW75184.1 - 0.21 12.4 4.0 0.22 12.4 0.3 2.5 1 1 1 2 2 2 0 Zinc-binding dehydrogenase Rtf2 PF04641.7 EIW75184.1 - 0.29 10.3 16.3 0.46 9.6 11.3 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger Ycf1 PF05758.7 EIW75184.1 - 0.58 7.8 6.7 0.56 7.8 4.7 1.1 1 0 0 1 1 1 0 Ycf1 Birna_RdRp PF04197.7 EIW75184.1 - 0.84 7.5 7.4 1 7.3 5.1 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) PLRV_ORF5 PF01690.12 EIW75184.1 - 2.3 7.2 9.5 2.6 7.0 6.6 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Atg14 PF10186.4 EIW75184.1 - 3.9 6.3 12.2 6 5.7 8.5 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 YihI PF04220.7 EIW75186.1 - 0.076 12.3 4.5 0.18 11.1 3.1 1.6 1 0 0 1 1 1 0 Der GTPase activator (YihI) Pox_A_type_inc PF04508.7 EIW75186.1 - 0.14 11.9 0.2 0.44 10.4 0.2 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF2333 PF10095.4 EIW75186.1 - 5.2 5.6 4.7 2.3 6.7 0.5 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2333) DUF4391 PF14335.1 EIW75187.1 - 0.017 14.5 0.0 0.15 11.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) F-box-like PF12937.2 EIW75187.1 - 0.033 13.9 0.6 0.12 12.0 0.4 2.1 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.2 EIW75187.1 - 4.1 7.1 10.3 3.4 7.4 0.9 4.9 5 1 2 7 7 7 0 Leucine Rich repeats (2 copies) AAA_17 PF13207.1 EIW75188.1 - 6.4e-11 43.1 0.0 8.6e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain 4HBT_2 PF13279.1 EIW75189.1 - 1.4e-05 25.5 0.0 1.8e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily 4HBT PF03061.17 EIW75189.1 - 0.035 14.2 0.0 0.068 13.2 0.0 1.6 1 1 0 1 1 1 0 Thioesterase superfamily Sipho_Gp37 PF14594.1 EIW75189.1 - 0.097 11.8 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Siphovirus ReqiPepy6 Gp37-like protein Cellulase PF00150.13 EIW75190.1 - 1.6e-14 53.8 2.4 4.4e-14 52.3 1.7 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_cc PF11790.3 EIW75190.1 - 0.00063 19.2 0.0 0.0011 18.4 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase catalytic core DUF3142 PF11340.3 EIW75191.1 - 0.033 13.8 0.1 0.43 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3142) F-box PF00646.28 EIW75191.1 - 0.039 13.6 0.3 0.13 11.9 0.2 1.9 1 0 0 1 1 1 0 F-box domain RFC1 PF08519.7 EIW75192.1 - 0.03 14.0 0.7 0.21 11.3 0.3 1.9 1 1 1 2 2 2 0 Replication factor RFC1 C terminal domain DUF2312 PF10073.4 EIW75192.1 - 0.038 13.3 0.9 0.99 8.8 0.1 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) zf-C2H2_2 PF12756.2 EIW75192.1 - 0.08 13.0 0.4 2.6 8.2 0.0 2.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Toxin_39 PF15500.1 EIW75192.1 - 0.098 12.7 1.2 0.74 9.9 0.1 2.0 2 0 0 2 2 2 0 Putative RNase-like toxin ComX PF05952.7 EIW75192.1 - 0.13 11.8 0.0 0.61 9.6 0.0 1.9 2 0 0 2 2 2 0 Bacillus competence pheromone ComX Transposase_21 PF02992.9 EIW75193.1 - 0.027 13.5 0.0 0.066 12.2 0.0 1.6 1 0 0 1 1 1 0 Transposase family tnp2 DUF4218 PF13960.1 EIW75193.1 - 0.2 11.0 0.1 0.43 10.0 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Lipase3_N PF03893.11 EIW75196.1 - 0.018 14.8 0.2 0.027 14.2 0.1 1.3 1 0 0 1 1 1 0 Lipase 3 N-terminal region Ovate PF04844.8 EIW75196.1 - 0.028 14.2 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Transcriptional repressor, ovate Lipase_3 PF01764.20 EIW75197.1 - 7.9e-16 57.9 0.0 9.9e-16 57.6 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) SFTA2 PF15210.1 EIW75197.1 - 0.024 14.2 0.4 0.055 13.0 0.2 1.6 1 1 0 1 1 1 0 Surfactant-associated protein 2 DAGAT PF03982.8 EIW75198.1 - 2e-87 292.6 0.0 1.7e-54 184.5 0.0 2.0 2 0 0 2 2 2 2 Diacylglycerol acyltransferase LRR_4 PF12799.2 EIW75199.1 - 0.00082 18.9 8.0 6.9 6.4 0.0 6.0 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW75199.1 - 0.0013 18.3 2.9 4.4 7.1 0.0 4.9 4 0 0 4 4 4 1 Leucine rich repeat LRR_7 PF13504.1 EIW75199.1 - 0.0061 16.5 2.4 2 8.9 0.2 5.4 6 0 0 6 6 6 1 Leucine rich repeat F-box-like PF12937.2 EIW75199.1 - 0.042 13.5 0.3 0.37 10.5 0.1 2.5 2 0 0 2 2 2 0 F-box-like LRR_6 PF13516.1 EIW75199.1 - 0.043 13.8 0.1 18 5.8 0.0 4.7 4 0 0 4 4 4 0 Leucine Rich repeat F-box-like PF12937.2 EIW75200.1 - 1.8e-06 27.5 2.8 5e-06 26.1 1.9 1.8 1 0 0 1 1 1 1 F-box-like DUF2184 PF09950.4 EIW75200.1 - 0.19 10.7 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2184) F-box PF00646.28 EIW75200.1 - 0.2 11.3 4.6 0.25 11.0 0.9 2.6 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 EIW75201.1 - 0.00035 20.2 0.2 0.0009 18.9 0.2 1.7 1 0 0 1 1 1 1 F-box-like NAD_binding_10 PF13460.1 EIW75203.1 - 4.5e-06 26.7 0.0 6.6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW75203.1 - 7.2e-05 22.3 0.0 9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EIW75203.1 - 0.014 15.6 0.1 0.033 14.4 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EIW75203.1 - 0.11 11.4 0.2 8.1 5.2 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein NAD_binding_10 PF13460.1 EIW75204.1 - 2e-05 24.7 0.0 3.1e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW75204.1 - 0.00012 21.6 0.0 0.00014 21.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EIW75204.1 - 0.013 15.7 0.2 0.08 13.2 0.1 1.9 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain F-box-like PF12937.2 EIW75205.1 - 4.4e-09 35.9 0.5 1.3e-08 34.4 0.3 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIW75206.1 - 4.5e-08 32.6 0.2 1e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like Na_H_Exchanger PF00999.16 EIW75206.1 - 0.15 10.5 0.0 0.21 10.0 0.0 1.1 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family KH_1 PF00013.24 EIW75207.1 - 2.1e-08 33.6 0.1 1.5e-06 27.7 0.1 2.3 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EIW75207.1 - 2.1e-05 24.0 0.5 0.00086 18.9 0.1 2.6 2 0 0 2 2 2 1 KH domain DUF4160 PF13711.1 EIW75207.1 - 0.00098 18.9 0.2 0.0025 17.6 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4160) F-box-like PF12937.2 EIW75209.1 - 0.00013 21.6 0.1 0.00035 20.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW75209.1 - 5.2 6.8 9.2 0.1 12.3 0.3 2.6 3 0 0 3 3 3 0 F-box domain Med15 PF09606.5 EIW75213.1 - 5.5 5.0 8.9 11 4.1 6.2 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal NAD_binding_10 PF13460.1 EIW75214.1 - 1.4e-05 25.2 0.1 2.4e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW75214.1 - 0.003 17.0 0.0 0.0052 16.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EIW75214.1 - 0.079 11.8 0.1 2.3 7.0 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein ubiquitin PF00240.18 EIW75216.1 - 0.00014 21.2 0.0 0.00016 20.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Pox_A_type_inc PF04508.7 EIW75219.1 - 0.02 14.6 1.1 0.074 12.8 0.7 2.0 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Methyltransf_33 PF10017.4 EIW75222.1 - 1.1e-30 106.1 0.1 1.6e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent F-box-like PF12937.2 EIW75223.1 - 0.0065 16.1 0.0 0.025 14.2 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIW75225.1 - 0.0074 15.9 0.0 0.028 14.1 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW75225.1 - 0.054 13.1 0.8 0.23 11.1 0.2 2.4 2 0 0 2 2 2 0 F-box domain TetR_C PF02909.12 EIW75225.1 - 0.08 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Tetracyclin repressor, C-terminal all-alpha domain DUF1989 PF09347.5 EIW75226.1 - 3.5e-51 172.9 0.0 4.4e-51 172.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) F-box-like PF12937.2 EIW75227.1 - 1.2e-07 31.3 0.4 3.9e-07 29.6 0.3 2.0 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIW75227.1 - 0.013 15.1 0.7 0.1 12.2 0.7 2.4 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Ytp1 PF10355.4 EIW75228.1 - 1.7e-71 240.6 14.1 1.7e-71 240.6 9.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EIW75228.1 - 1.6e-27 95.1 0.2 1.6e-27 95.1 0.1 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) Cellulase PF00150.13 EIW75230.1 - 2.1e-15 56.6 0.0 5e-15 55.4 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) WD40 PF00400.27 EIW75232.1 - 2.4e-26 90.6 3.6 1.8e-09 37.1 0.0 5.8 5 1 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 EIW75232.1 - 0.0021 16.2 0.0 0.039 12.1 0.0 2.2 2 0 0 2 2 2 1 Nucleoporin Nup120/160 DUF4123 PF13503.1 EIW75232.1 - 0.066 13.1 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) RNA_pol_Rpc4 PF05132.9 EIW75232.1 - 3.4 7.6 0.0 3.4 7.6 0.0 3.3 3 1 0 3 3 3 0 RNA polymerase III RPC4 PPP4R2 PF09184.6 EIW75232.1 - 5 6.5 16.0 8.6 5.8 11.1 1.4 1 0 0 1 1 1 0 PPP4R2 Abhydrolase_2 PF02230.11 EIW75233.1 - 1.1e-33 116.5 0.0 1.4e-33 116.1 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EIW75233.1 - 1.7e-06 27.8 0.0 3e-06 27.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EIW75233.1 - 0.00051 19.5 0.0 0.00059 19.3 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EIW75233.1 - 0.0012 18.7 0.2 0.0055 16.6 0.1 1.9 2 1 1 3 3 3 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EIW75233.1 - 0.0069 15.9 0.0 0.0081 15.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 EIW75233.1 - 0.094 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Cutinase DUF3089 PF11288.3 EIW75233.1 - 0.18 10.9 0.1 0.26 10.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Cellulase PF00150.13 EIW75234.1 - 9.3e-15 54.5 0.1 1.8e-14 53.6 0.0 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) KRTAP7 PF15034.1 EIW75234.1 - 0.0026 18.3 0.6 0.12 13.0 0.0 2.9 2 0 0 2 2 2 1 KRTAP type 7 family STE3 PF02076.10 EIW75235.1 - 8.9e-34 116.8 9.4 1.1e-33 116.6 6.5 1.0 1 0 0 1 1 1 1 Pheromone A receptor CAP_GLY PF01302.20 EIW75236.1 - 4.4e-27 93.5 0.6 7.3e-27 92.8 0.4 1.4 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EIW75236.1 - 5.4e-23 81.0 0.0 8.7e-23 80.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EIW75236.1 - 0.0013 18.0 0.0 0.0077 15.6 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin family AAA PF00004.24 EIW75237.1 - 2.5e-97 322.1 0.0 3.4e-47 159.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EIW75237.1 - 4.1e-20 71.5 0.5 5.3e-19 67.9 0.2 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 EIW75237.1 - 7.9e-14 51.2 0.0 8.7e-06 24.9 0.0 3.0 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EIW75237.1 - 2e-13 50.5 0.0 1.3e-07 31.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EIW75237.1 - 1.1e-12 48.0 0.0 1.9e-06 27.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EIW75237.1 - 1.6e-12 48.3 0.2 0.00011 23.0 0.0 3.4 2 1 1 3 3 2 2 AAA domain AAA_5 PF07728.9 EIW75237.1 - 3.5e-12 46.2 0.4 5.1e-06 26.2 0.1 3.7 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EIW75237.1 - 1.2e-11 44.8 0.1 0.0019 18.3 0.0 4.3 3 2 0 3 3 2 2 AAA domain CDC48_2 PF02933.12 EIW75237.1 - 8.7e-11 41.3 0.0 1.7e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_16 PF13191.1 EIW75237.1 - 1.7e-10 41.2 0.0 0.0012 18.8 0.0 3.4 3 2 0 3 3 2 2 AAA ATPase domain TIP49 PF06068.8 EIW75237.1 - 1.8e-09 36.8 0.0 0.001 17.8 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 EIW75237.1 - 3.1e-08 33.2 2.5 0.014 14.7 0.0 3.8 2 2 1 4 4 4 2 AAA domain IstB_IS21 PF01695.12 EIW75237.1 - 6.3e-08 32.2 0.0 0.0043 16.4 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.1 EIW75237.1 - 6.7e-08 32.4 0.0 0.0037 17.1 0.0 2.9 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 EIW75237.1 - 8.9e-08 31.4 0.0 0.0097 15.0 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin Mg_chelatase PF01078.16 EIW75237.1 - 1.5e-07 30.7 0.3 0.013 14.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Vps4_C PF09336.5 EIW75237.1 - 1.6e-07 31.1 0.0 2.2e-06 27.4 0.0 2.6 2 1 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_19 PF13245.1 EIW75237.1 - 2.1e-07 30.6 2.1 0.0077 15.9 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain RNA_helicase PF00910.17 EIW75237.1 - 4.1e-07 30.1 0.0 0.019 15.1 0.0 2.9 2 0 0 2 2 2 2 RNA helicase KaiC PF06745.8 EIW75237.1 - 1.5e-06 27.4 0.6 0.45 9.5 0.0 3.5 2 1 1 3 3 3 2 KaiC AAA_18 PF13238.1 EIW75237.1 - 1.7e-06 28.3 0.2 0.032 14.5 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.1 EIW75237.1 - 2e-06 27.8 0.4 0.1 12.5 0.0 3.6 3 1 0 4 4 4 2 AAA domain Parvo_NS1 PF01057.12 EIW75237.1 - 3.1e-06 26.2 0.2 0.011 14.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_24 PF13479.1 EIW75237.1 - 4.7e-06 26.3 0.0 0.1 12.1 0.0 3.0 3 0 0 3 3 2 2 AAA domain ResIII PF04851.10 EIW75237.1 - 7.5e-06 25.9 0.0 0.0036 17.1 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activat PF00158.21 EIW75237.1 - 1.7e-05 24.3 0.0 0.37 10.2 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain Bac_DnaA PF00308.13 EIW75237.1 - 1.8e-05 24.4 0.0 0.12 12.0 0.0 2.7 3 0 0 3 3 2 2 Bacterial dnaA protein DUF815 PF05673.8 EIW75237.1 - 2e-05 23.6 0.0 0.014 14.2 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 EIW75237.1 - 3.3e-05 23.7 0.1 0.57 9.8 0.1 3.7 3 1 1 4 4 3 1 Archaeal ATPase Sigma54_activ_2 PF14532.1 EIW75237.1 - 4.9e-05 23.3 0.0 0.33 10.9 0.0 3.0 3 0 0 3 3 2 2 Sigma-54 interaction domain PhoH PF02562.11 EIW75237.1 - 9.4e-05 21.7 0.3 0.28 10.3 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein ABC_tran PF00005.22 EIW75237.1 - 0.00011 22.5 0.0 0.35 11.1 0.0 3.4 2 1 0 2 2 2 1 ABC transporter AAA_3 PF07726.6 EIW75237.1 - 0.00015 21.3 0.0 0.57 9.8 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EIW75237.1 - 0.00016 21.3 0.0 0.63 9.5 0.0 2.6 2 1 0 2 2 2 2 AAA domain NACHT PF05729.7 EIW75237.1 - 0.00025 20.7 0.0 0.68 9.5 0.0 3.4 3 0 0 3 3 3 1 NACHT domain DUF2075 PF09848.4 EIW75237.1 - 0.00031 19.8 0.0 0.4 9.6 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EIW75237.1 - 0.0011 18.5 0.0 2.2 7.8 0.0 2.8 3 0 0 3 3 2 1 AAA domain T2SE PF00437.15 EIW75237.1 - 0.0015 17.4 0.0 0.11 11.3 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein NB-ARC PF00931.17 EIW75237.1 - 0.0018 17.1 0.0 0.44 9.3 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Viral_helicase1 PF01443.13 EIW75237.1 - 0.0026 17.2 0.0 0.23 10.9 0.0 2.6 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 EIW75237.1 - 0.005 16.5 1.0 1.9 8.1 0.0 3.8 4 0 0 4 4 4 1 NTPase KAP_NTPase PF07693.9 EIW75237.1 - 0.02 13.9 0.1 0.94 8.4 0.0 2.7 2 2 1 3 3 3 0 KAP family P-loop domain PIF1 PF05970.9 EIW75237.1 - 0.029 13.3 0.0 7.7 5.3 0.0 3.5 3 0 0 3 3 3 0 PIF1-like helicase UPF0079 PF02367.12 EIW75237.1 - 0.031 13.9 0.1 3.7 7.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 IPT PF01745.11 EIW75237.1 - 0.032 13.4 0.0 2 7.5 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase SKI PF01202.17 EIW75237.1 - 0.058 13.2 0.7 3.8 7.3 0.0 2.8 3 0 0 3 3 2 0 Shikimate kinase Zot PF05707.7 EIW75237.1 - 0.059 12.8 0.2 13 5.2 0.1 3.4 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Molydop_binding PF01568.16 EIW75237.1 - 0.09 12.5 0.0 0.2 11.5 0.0 1.5 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain UFD1 PF03152.9 EIW75237.1 - 0.1 11.7 0.0 0.36 9.9 0.0 1.7 1 1 1 2 2 2 0 Ubiquitin fusion degradation protein UFD1 AAA_10 PF12846.2 EIW75237.1 - 0.14 11.5 0.8 7.2 5.9 0.0 3.5 3 1 1 4 4 4 0 AAA-like domain KTI12 PF08433.5 EIW75237.1 - 0.14 11.3 0.1 12 5.0 0.0 2.7 3 0 0 3 3 2 0 Chromatin associated protein KTI12 DEAD PF00270.24 EIW75237.1 - 0.14 11.6 0.3 62 3.0 0.0 3.4 2 1 1 3 3 3 0 DEAD/DEAH box helicase ATP-synt_ab PF00006.20 EIW75237.1 - 0.15 11.5 0.0 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 EIW75237.1 - 0.27 10.9 1.0 11 5.7 0.0 3.4 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B Abhydrolase_2 PF02230.11 EIW75238.1 - 1.2e-32 113.1 0.0 4.2e-29 101.5 0.0 3.0 2 1 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EIW75238.1 - 5.6e-05 22.9 0.0 0.00019 21.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EIW75238.1 - 0.045 13.1 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) AA_permease PF00324.16 EIW75239.1 - 5.6e-113 377.8 41.2 9.9e-64 215.4 9.8 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EIW75239.1 - 1.4e-32 112.8 37.6 1.6e-32 112.5 25.6 1.4 1 1 1 2 2 2 1 Amino acid permease DUF1604 PF07713.8 EIW75240.1 - 4.3e-37 125.7 0.8 4.3e-37 125.7 0.6 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EIW75240.1 - 3.2e-06 26.8 1.0 8.9e-06 25.3 0.1 2.3 2 0 0 2 2 2 1 G-patch domain Abhydrolase_2 PF02230.11 EIW75245.1 - 4.1e-24 85.2 0.7 3.4e-14 52.8 0.0 3.8 2 2 1 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EIW75245.1 - 2.9e-05 23.8 0.1 6.6e-05 22.6 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EIW75245.1 - 0.0051 16.2 0.1 0.015 14.7 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Cutinase PF01083.17 EIW75245.1 - 0.13 12.0 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Cutinase RhoGEF PF00621.15 EIW75246.1 - 3e-68 229.2 0.4 7e-35 120.5 0.1 2.2 2 0 0 2 2 2 2 RhoGEF domain CNH PF00780.17 EIW75246.1 - 1.7e-61 208.0 0.0 2.6e-61 207.4 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 EIW75246.1 - 7.4e-16 58.3 0.0 2.1e-15 56.8 0.0 1.8 2 0 0 2 2 2 1 Pleckstrin homology domain DEP PF00610.16 EIW75246.1 - 0.00016 21.3 0.0 0.00033 20.3 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.24 EIW75246.1 - 0.0071 16.5 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 PH domain Methyltransf_23 PF13489.1 EIW75247.1 - 4.9e-12 45.8 0.0 9e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW75247.1 - 1.1e-09 38.6 0.0 2.5e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW75247.1 - 2.1e-08 34.5 0.0 1.6e-07 31.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW75247.1 - 2.6e-08 34.1 0.0 7.8e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW75247.1 - 1.2e-06 29.0 0.0 2.8e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW75247.1 - 4.5e-06 26.6 1.5 2.1e-05 24.5 0.1 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW75247.1 - 3.8e-05 23.3 0.0 0.0001 21.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW75247.1 - 0.0038 16.3 0.0 0.0064 15.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EIW75247.1 - 0.0066 15.8 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.10 EIW75247.1 - 0.011 15.4 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_24 PF13578.1 EIW75247.1 - 0.016 15.9 0.0 0.036 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FmrO PF07091.6 EIW75247.1 - 0.027 13.4 0.0 0.048 12.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Abhydrolase_2 PF02230.11 EIW75249.1 - 4.3e-26 91.7 2.6 3.5e-17 62.5 1.1 3.9 2 2 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EIW75249.1 - 0.00057 19.6 0.1 0.0033 17.1 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EIW75249.1 - 0.0015 18.0 0.0 0.0032 16.9 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EIW75249.1 - 0.0097 15.8 0.0 0.022 14.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EIW75249.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Cutinase PF01083.17 EIW75249.1 - 0.15 11.7 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Cutinase Tri3 PF07428.6 EIW75253.1 - 1.4e-10 40.5 0.0 1.9e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 15-O-acetyltransferase Tri3 F-box-like PF12937.2 EIW75259.1 - 0.00035 20.2 1.9 0.00064 19.3 0.8 1.9 2 0 0 2 2 2 1 F-box-like Abhydrolase_2 PF02230.11 EIW75260.1 - 1.8e-34 119.1 0.0 2.7e-34 118.4 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EIW75260.1 - 6.8e-13 49.0 1.8 8.8e-13 48.6 1.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW75260.1 - 1.3e-12 47.7 0.2 1.6e-12 47.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EIW75260.1 - 1.6e-06 27.8 0.1 2.5e-06 27.2 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIW75260.1 - 2.5e-06 26.8 0.3 0.00018 20.8 0.0 2.7 2 1 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.15 EIW75260.1 - 1e-05 25.1 0.4 0.00018 21.0 0.3 2.2 1 1 0 1 1 1 1 Putative esterase FSH1 PF03959.8 EIW75260.1 - 2.6e-05 23.7 0.0 7.4e-05 22.2 0.0 1.8 1 1 1 2 2 2 1 Serine hydrolase (FSH1) Thioesterase PF00975.15 EIW75260.1 - 7e-05 23.1 0.0 0.0001 22.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.20 EIW75260.1 - 0.043 13.4 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Cutinase PF01083.17 EIW75260.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Cutinase Mito_carr PF00153.22 EIW75261.1 - 4.8e-66 218.5 2.7 1.3e-23 82.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_Rbc25 PF08292.7 EIW75262.1 - 3.7e-29 101.4 0.0 4.8e-29 101.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EIW75262.1 - 2.4e-20 72.4 0.1 4.1e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Helitron_like_N PF14214.1 EIW75268.1 - 7.8e-37 126.7 0.0 8.9e-37 126.5 0.0 1.0 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus Abhydrolase_2 PF02230.11 EIW75270.1 - 5.3e-18 65.2 0.0 4.2e-17 62.3 0.0 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EIW75270.1 - 1.9e-07 30.9 1.3 3.1e-07 30.2 0.9 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW75270.1 - 1.2e-06 28.6 4.2 2.3e-06 27.6 2.9 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EIW75270.1 - 1.3e-05 24.7 0.0 2.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) FSH1 PF03959.8 EIW75270.1 - 5.5e-05 22.7 0.0 7.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Esterase PF00756.15 EIW75270.1 - 0.006 16.0 0.2 0.014 14.8 0.1 1.6 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.8 EIW75270.1 - 0.071 12.6 0.3 0.1 12.1 0.2 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIW75270.1 - 0.14 11.3 0.7 1.9 7.6 0.3 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EIW75275.1 - 3.8e-34 118.0 0.0 2.8e-33 115.2 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EIW75275.1 - 4.1e-08 33.0 0.1 5.7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW75275.1 - 1.5e-07 31.5 0.1 2e-07 31.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EIW75275.1 - 2.3e-07 30.4 0.1 7.2e-07 28.8 0.0 1.9 1 1 1 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EIW75275.1 - 9.7e-07 28.5 0.0 1.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Cutinase PF01083.17 EIW75275.1 - 0.0011 18.6 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Cutinase Peptidase_S9 PF00326.16 EIW75275.1 - 0.011 15.0 0.4 0.72 9.0 0.0 2.7 1 1 0 2 2 2 0 Prolyl oligopeptidase family DUF2974 PF11187.3 EIW75275.1 - 0.013 14.8 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) F-box-like PF12937.2 EIW75276.1 - 0.032 13.9 2.2 0.032 13.9 1.5 3.0 3 0 0 3 3 3 0 F-box-like BNR PF02012.15 EIW75279.1 - 6.6e-09 34.2 45.0 1.9 8.6 0.0 11.1 11 0 0 11 11 11 8 BNR/Asp-box repeat PSII_BNR PF14870.1 EIW75279.1 - 2.5e-06 26.7 0.2 0.11 11.4 0.0 3.7 3 0 0 3 3 3 2 Photosynthesis system II assembly factor YCF48 Fe_dep_repr_C PF02742.10 EIW75279.1 - 0.0051 16.4 0.0 0.14 11.8 0.0 2.4 2 0 0 2 2 2 1 Iron dependent repressor, metal binding and dimerisation domain DUF4131 PF13567.1 EIW75279.1 - 3.3 7.1 5.6 9.1 5.6 0.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) SHS2_Rpb7-N PF03876.12 EIW75280.1 - 2.4e-14 53.1 0.0 4.4e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EIW75280.1 - 1.8e-11 43.9 1.1 4.1e-11 42.8 0.8 1.5 1 1 0 1 1 1 1 S1 RNA binding domain RNA_pol_Rbc25 PF08292.7 EIW75280.1 - 0.035 14.3 0.1 0.067 13.3 0.0 1.6 1 1 0 1 1 1 0 RNA polymerase III subunit Rpc25 CytB6-F_Fe-S PF08802.5 EIW75281.1 - 0.69 9.9 3.6 7.5 6.6 0.1 2.5 2 1 0 2 2 2 0 Cytochrome B6-F complex Fe-S subunit Amidase PF01425.16 EIW75283.1 - 4.1e-113 378.5 1.7 6.1e-113 377.9 1.2 1.2 1 0 0 1 1 1 1 Amidase F-box-like PF12937.2 EIW75285.1 - 0.031 14.0 0.8 0.031 14.0 0.5 2.2 3 0 0 3 3 3 0 F-box-like DnaJ PF00226.26 EIW75286.1 - 1.6e-11 43.7 0.0 3.6e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain dCMP_cyt_deam_1 PF00383.17 EIW75287.1 - 1.3e-17 63.3 0.0 1.8e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EIW75287.1 - 5.7e-11 42.5 0.1 2.4e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EIW75287.1 - 7.8e-05 22.1 1.4 0.15 11.4 0.0 2.2 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases zf-B_box PF00643.19 EIW75289.1 - 0.19 11.6 13.1 0.035 14.0 5.8 2.3 2 0 0 2 2 2 0 B-box zinc finger DUF4218 PF13960.1 EIW75291.1 - 0.0068 15.8 0.0 0.037 13.4 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) Peptidase_S10 PF00450.17 EIW75294.1 - 3.9e-97 326.0 0.7 5.7e-97 325.5 0.5 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EIW75294.1 - 5.6e-08 32.9 0.1 2.7e-07 30.6 0.0 2.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW75294.1 - 0.00075 19.2 0.0 0.0023 17.6 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family MSP PF01716.13 EIW75294.1 - 0.1 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Manganese-stabilising protein / photosystem II polypeptide Pyr_redox_2 PF07992.9 EIW75295.1 - 1.6e-16 60.7 0.0 1.8e-10 41.0 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIW75295.1 - 2e-16 59.2 0.2 5.3e-13 48.0 0.0 2.9 2 1 1 3 3 3 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EIW75295.1 - 1.2e-15 58.0 0.5 1.2e-09 38.4 0.0 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW75295.1 - 1.7e-08 34.7 0.0 0.006 16.9 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIW75295.1 - 2.8e-08 33.1 0.2 1.9e-05 23.8 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.1 EIW75295.1 - 1.4e-07 30.7 0.0 3.4e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.19 EIW75295.1 - 5.7e-07 28.7 0.4 8.3e-06 24.8 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EIW75295.1 - 1e-06 28.6 1.6 1.2e-05 25.1 0.0 3.1 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EIW75295.1 - 8.8e-06 24.4 0.8 2.5e-05 22.9 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein 3HCDH_N PF02737.13 EIW75295.1 - 9.2e-06 25.4 0.0 0.058 13.0 0.0 2.2 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EIW75295.1 - 2.9e-05 23.3 0.0 5.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EIW75295.1 - 6.5e-05 22.1 0.0 0.094 11.8 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EIW75295.1 - 7.9e-05 22.4 0.9 0.094 12.4 0.0 3.1 3 1 1 4 4 3 2 FAD-NAD(P)-binding GIDA PF01134.17 EIW75295.1 - 0.00016 20.6 0.7 0.0041 16.0 0.0 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A Shikimate_DH PF01488.15 EIW75295.1 - 0.00022 21.3 0.0 0.21 11.6 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase CPSase_L_chain PF00289.17 EIW75295.1 - 0.00034 20.6 0.0 0.098 12.7 0.0 2.4 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Lycopene_cycl PF05834.7 EIW75295.1 - 0.00084 18.3 0.1 0.015 14.2 0.0 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.12 EIW75295.1 - 0.001 18.2 0.0 0.02 14.0 0.0 2.2 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EIW75295.1 - 0.001 18.0 0.7 0.023 13.6 0.2 3.0 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EIW75295.1 - 0.0023 18.1 0.0 3.3 8.0 0.0 2.4 2 0 0 2 2 2 2 Putative NAD(P)-binding IlvN PF07991.7 EIW75295.1 - 0.0069 15.7 0.0 0.095 12.0 0.0 2.2 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain AlaDh_PNT_C PF01262.16 EIW75295.1 - 0.008 15.7 0.2 0.2 11.2 0.0 2.5 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain AdoHcyase_NAD PF00670.16 EIW75295.1 - 0.039 13.8 0.2 9.7 6.0 0.0 2.5 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ThiF PF00899.16 EIW75295.1 - 0.061 13.1 0.2 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 ThiF family TrkA_N PF02254.13 EIW75295.1 - 0.096 12.6 0.0 4.4 7.3 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 EIW75295.1 - 0.13 11.5 0.0 3.3 7.0 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UbiA PF01040.13 EIW75296.1 - 6.7e-05 22.2 1.2 6.7e-05 22.2 0.9 2.0 1 1 1 2 2 2 1 UbiA prenyltransferase family DUF981 PF06168.6 EIW75296.1 - 0.008 15.9 0.3 0.008 15.9 0.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF981) p450 PF00067.17 EIW75297.1 - 3.7e-11 42.2 0.9 4e-11 42.1 0.6 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S10 PF00450.17 EIW75298.1 - 2.5e-93 313.5 0.0 3.5e-93 313.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EIW75298.1 - 0.0022 17.9 0.0 0.0081 16.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Vpu PF00558.14 EIW75299.1 - 0.016 14.7 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Vpu protein 2OG-FeII_Oxy PF03171.15 EIW75300.1 - 1.2e-23 83.2 0.0 1.8e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EIW75300.1 - 1.4e-15 57.8 0.0 2.6e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DUF4243 PF14027.1 EIW75301.1 - 3.3e-79 266.7 0.1 4e-79 266.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) IncA PF04156.9 EIW75302.1 - 0.006 16.1 7.6 0.006 16.1 5.3 5.7 1 1 2 4 4 4 1 IncA protein Fib_alpha PF08702.5 EIW75302.1 - 0.049 13.7 46.1 0.089 12.9 5.2 5.9 2 2 4 6 6 6 0 Fibrinogen alpha/beta chain family Reo_sigmaC PF04582.7 EIW75302.1 - 1.4 8.0 34.3 1.2 8.2 1.0 5.8 1 1 4 6 6 6 0 Reovirus sigma C capsid protein DUF4451 PF14616.1 EIW75303.1 - 8.2e-10 38.5 8.2 0.099 12.4 0.3 4.2 3 1 1 4 4 4 4 Domain of unknown function (DUF4451) Ecl1 PF12855.2 EIW75303.1 - 0.85 8.9 8.5 0.14 11.5 0.2 3.1 3 0 0 3 3 3 0 Life-span regulatory factor DUF4182 PF13790.1 EIW75303.1 - 2.4 8.0 4.4 25 4.7 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4182) Tnp_zf-ribbon_2 PF13842.1 EIW75303.1 - 4.3 7.8 9.9 32 5.0 0.1 4.4 4 0 0 4 4 4 0 DDE_Tnp_1-like zinc-ribbon GLTP PF08718.6 EIW75304.1 - 3.8e-31 108.1 0.0 4.7e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) TATR PF03430.8 EIW75305.1 - 0.03 12.9 7.9 0.042 12.5 5.5 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Fungal_trans PF04082.13 EIW75306.1 - 5.6e-19 68.0 0.1 9.6e-19 67.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW75306.1 - 1.6e-05 24.7 14.3 3e-05 23.8 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cu-oxidase PF00394.17 EIW75307.1 - 3.7e-41 140.6 5.0 1.1e-40 139.1 0.0 3.4 5 0 0 5 5 5 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIW75307.1 - 1.9e-40 137.2 6.1 1.7e-37 127.7 0.4 3.1 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIW75307.1 - 4.5e-40 136.3 4.9 1.5e-33 115.2 0.1 4.1 3 1 0 3 3 3 3 Multicopper oxidase SRF-TF PF00319.13 EIW75308.1 - 3.4e-18 64.6 0.0 6.8e-18 63.6 0.0 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) MFS_1 PF07690.11 EIW75310.1 - 4.5e-14 51.9 41.2 8.1e-14 51.0 28.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Spore_permease PF03845.8 EIW75311.1 - 0.023 13.3 0.2 0.03 13.0 0.2 1.1 1 0 0 1 1 1 0 Spore germination protein MFS_2 PF13347.1 EIW75311.1 - 0.11 10.9 0.1 0.13 10.6 0.1 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein DUF1900 PF08954.6 EIW75312.1 - 3.8e-44 149.5 0.0 9.3e-43 145.0 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EIW75312.1 - 1.3e-27 95.2 0.0 2.1e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EIW75312.1 - 1.3e-23 81.9 4.4 3.8e-08 32.8 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat CCDC144C PF14915.1 EIW75312.1 - 0.028 13.3 1.7 0.038 12.8 1.2 1.1 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Nup160 PF11715.3 EIW75312.1 - 0.058 11.5 0.1 0.4 8.7 0.0 1.9 1 1 0 2 2 2 0 Nucleoporin Nup120/160 DUF3391 PF11871.3 EIW75312.1 - 0.1 12.7 0.8 0.18 11.9 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) MFS_1 PF07690.11 EIW75313.1 - 2.9e-26 92.0 43.3 2.1e-13 49.6 17.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Cu-oxidase PF00394.17 EIW75314.1 - 9.8e-46 155.5 0.6 4.2e-43 147.0 0.0 2.8 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIW75314.1 - 1.7e-41 140.6 3.3 5.5e-39 132.5 0.8 2.9 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIW75314.1 - 2e-37 127.8 10.9 2e-35 121.3 0.7 4.0 3 1 0 3 3 3 2 Multicopper oxidase Peptidase_M28 PF04389.12 EIW75315.1 - 1.1e-27 96.9 0.0 1.8e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Cu-oxidase PF00394.17 EIW75316.1 - 4.3e-46 156.7 0.6 4.3e-46 156.7 0.4 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIW75316.1 - 6.1e-39 132.4 1.3 1.1e-37 128.3 0.3 2.7 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIW75316.1 - 9.6e-35 119.0 9.7 9.1e-34 115.9 0.4 3.5 3 1 0 3 3 3 2 Multicopper oxidase SepZ PF06066.6 EIW75316.1 - 0.06 13.3 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 SepZ XPG_I PF00867.13 EIW75317.1 - 2.1e-21 75.7 0.0 3.8e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 EIW75317.1 - 0.0026 17.3 0.0 0.0034 16.9 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing XPG_N PF00752.12 EIW75317.1 - 0.02 15.1 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 XPG N-terminal domain MAPEG PF01124.13 EIW75320.1 - 5.1e-17 61.6 0.2 6.6e-17 61.3 0.1 1.1 1 0 0 1 1 1 1 MAPEG family SNF5 PF04855.7 EIW75321.1 - 0.00066 19.2 0.0 0.00087 18.8 0.0 1.3 1 1 0 1 1 1 1 SNF5 / SMARCB1 / INI1 DUF2798 PF11391.3 EIW75321.1 - 0.03 14.0 2.9 0.05 13.3 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2798) Dimer_Tnp_hAT PF05699.9 EIW75322.1 - 5.3e-14 51.6 0.4 6.1e-14 51.4 0.3 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RCC1 PF00415.13 EIW75324.1 - 2.9e-36 123.4 15.0 3.3e-11 43.2 0.2 7.4 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EIW75324.1 - 1.3e-21 75.6 15.0 2.1e-06 27.1 0.1 6.0 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat PHD PF00628.24 EIW75324.1 - 1.7e-10 40.4 5.8 1.7e-10 40.4 4.0 2.4 3 0 0 3 3 3 1 PHD-finger Prok-RING_1 PF14446.1 EIW75324.1 - 0.016 14.9 3.0 0.016 14.9 2.1 3.2 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 SQS_PSY PF00494.14 EIW75325.1 - 1.9e-45 155.2 0.0 2.7e-45 154.7 0.0 1.2 1 0 0 1 1 1 1 Squalene/phytoene synthase Cu-oxidase PF00394.17 EIW75328.1 - 1.4e-46 158.3 0.2 2.5e-45 154.2 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIW75328.1 - 6.8e-37 126.0 8.9 1e-33 115.7 0.8 3.7 4 1 0 4 4 4 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIW75328.1 - 3.1e-36 123.6 0.7 6.1e-33 113.0 0.1 3.2 3 1 0 3 3 3 2 Multicopper oxidase Methyltransf_15 PF09445.5 EIW75329.1 - 6.7e-35 120.0 0.0 3e-27 95.1 0.0 2.2 2 0 0 2 2 2 2 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 EIW75329.1 - 9.8e-10 39.0 0.0 1.5e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW75329.1 - 1.2e-08 34.9 0.0 1.9e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW75329.1 - 1.9e-06 28.1 0.0 4.1e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW75329.1 - 4.2e-06 26.4 0.0 5.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EIW75329.1 - 8.6e-06 25.4 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 EIW75329.1 - 2.6e-05 23.7 0.0 4.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.13 EIW75329.1 - 3e-05 23.6 0.0 5.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.8 EIW75329.1 - 0.0024 17.0 0.0 0.0037 16.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EIW75329.1 - 0.0055 17.1 0.0 0.0098 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EIW75329.1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase tRNA_U5-meth_tr PF05958.6 EIW75329.1 - 0.025 13.2 0.0 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_3 PF01596.12 EIW75329.1 - 0.12 11.3 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Ubie_methyltran PF01209.13 EIW75329.1 - 0.17 10.9 0.0 0.45 9.5 0.0 1.6 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family GCV_T PF01571.16 EIW75330.1 - 6.4e-66 221.7 0.0 8.1e-66 221.3 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EIW75330.1 - 3.8e-24 84.5 0.3 9.2e-24 83.3 0.2 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain VPS28 PF03997.7 EIW75331.1 - 1.4e-60 204.1 0.0 1.6e-60 203.9 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein AsnC_trans_reg PF01037.16 EIW75331.1 - 0.021 14.4 0.0 0.046 13.4 0.0 1.6 1 0 0 1 1 1 0 AsnC family HAD_2 PF13419.1 EIW75332.1 - 3.2e-20 73.0 0.0 4.6e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIW75332.1 - 8e-13 49.2 0.0 6e-12 46.4 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIW75332.1 - 2.1e-07 30.5 0.0 4.3e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EIW75332.1 - 0.0047 16.8 0.0 0.28 11.0 0.0 2.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 EIW75332.1 - 0.0047 17.1 0.0 0.009 16.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PhzC-PhzF PF02567.11 EIW75333.1 - 1.3e-35 123.0 0.0 1.6e-35 122.6 0.0 1.0 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein DUF4218 PF13960.1 EIW75335.1 - 0.0037 16.6 0.1 0.0068 15.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) FAM163 PF15069.1 EIW75339.1 - 0.0031 18.0 0.6 0.0046 17.5 0.4 1.2 1 0 0 1 1 1 1 FAM163 family zf-LITAF-like PF10601.4 EIW75339.1 - 0.011 15.5 0.1 3.6 7.5 0.0 2.4 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain DUF2321 PF10083.4 EIW75339.1 - 0.038 13.4 0.2 0.056 12.9 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) DUF3092 PF11289.3 EIW75340.1 - 0.15 11.2 0.6 0.15 11.2 0.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3092) zf-C2H2 PF00096.21 EIW75343.1 - 0.024 14.9 1.0 0.085 13.2 0.7 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type Cyclin_N PF00134.18 EIW75344.1 - 3.2e-11 42.9 0.1 3.8e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EIW75344.1 - 2.2e-09 37.9 0.0 2.5e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin Prp19 PF08606.6 EIW75344.1 - 0.11 12.2 0.4 13 5.5 0.2 2.5 2 0 0 2 2 2 0 Prp19/Pso4-like DUF605 PF04652.11 EIW75345.1 - 6.2 6.1 16.4 6.9 5.9 11.4 1.1 1 0 0 1 1 1 0 Vta1 like Phage_integrase PF00589.17 EIW75346.1 - 0.0015 18.2 0.0 0.0025 17.5 0.0 1.3 1 1 0 1 1 1 1 Phage integrase family Helicase_C PF00271.26 EIW75348.1 - 4.7e-13 48.7 0.0 9.2e-13 47.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EIW75348.1 - 0.0048 15.7 0.1 0.0076 15.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF3525 PF12039.3 EIW75348.1 - 0.13 10.7 0.0 0.38 9.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3525) Zn_clus PF00172.13 EIW75350.1 - 0.00094 19.0 8.1 0.21 11.5 1.4 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Tet_JBP PF12851.2 EIW75351.1 - 5.6e-11 42.0 0.0 6.9e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily DEAD PF00270.24 EIW75352.1 - 0.019 14.4 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase DPM3 PF08285.6 EIW75353.1 - 0.24 11.2 0.1 4 7.3 0.1 2.4 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF1183 PF06682.7 EIW75355.1 - 1.7e-37 129.7 0.3 1.9e-37 129.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) SNF2_N PF00176.18 EIW75356.1 - 2.4e-44 151.3 0.1 3.4e-44 150.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EIW75356.1 - 0.1 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-RVT PF13966.1 EIW75360.1 - 0.0071 16.6 0.1 0.011 16.0 0.1 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF1569 PF07606.6 EIW75360.1 - 0.058 13.3 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1569) TatD_DNase PF01026.16 EIW75360.1 - 0.065 12.4 0.0 0.07 12.3 0.0 1.0 1 0 0 1 1 1 0 TatD related DNase Pkinase PF00069.20 EIW75362.1 - 1.8e-30 105.9 0.0 2.3e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW75362.1 - 3.4e-10 39.4 0.0 5.1e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW75362.1 - 0.029 14.1 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW75362.1 - 0.057 12.3 0.0 0.08 11.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like PT PF04886.7 EIW75363.1 - 9.7e-05 21.6 8.1 9.7e-05 21.6 5.6 3.2 2 1 0 2 2 2 1 PT repeat hNIFK_binding PF12196.3 EIW75363.1 - 0.11 11.8 0.9 0.47 9.8 0.6 2.0 1 0 0 1 1 1 0 FHA Ki67 binding domain of hNIFK BSP_II PF05432.6 EIW75363.1 - 0.13 11.5 13.8 0.02 14.1 2.9 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) MIP-T3 PF10243.4 EIW75363.1 - 3.5 5.9 12.8 5.5 5.3 8.9 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Nop14 PF04147.7 EIW75363.1 - 4.3 5.1 7.7 1.1 7.0 0.7 2.0 2 0 0 2 2 2 0 Nop14-like family CENP-B_dimeris PF09026.5 EIW75363.1 - 4.6 7.5 17.5 7.3 6.8 5.7 2.5 2 1 0 2 2 2 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 EIW75363.1 - 5.4 6.5 8.2 2.5 7.5 1.5 2.2 2 0 0 2 2 2 0 Nucleoplasmin IER PF05760.7 EIW75363.1 - 8.4 6.2 19.4 4.5 7.1 11.9 1.5 1 1 0 1 1 1 0 Immediate early response protein (IER) Cse1 PF08506.5 EIW75368.1 - 4.2e-26 91.3 0.0 1.5e-24 86.2 0.0 2.2 2 0 0 2 2 2 2 Cse1 CAS_CSE1 PF03378.10 EIW75368.1 - 3.5e-24 84.8 0.1 4.4e-24 84.5 0.1 1.1 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.5 EIW75369.1 - 0.019 13.5 0.0 0.019 13.5 0.0 1.1 1 0 0 1 1 1 0 Cse1 HSP70 PF00012.15 EIW75370.1 - 0.0026 15.7 0.0 0.0042 15.0 0.0 1.2 1 0 0 1 1 1 1 Hsp70 protein Glyco_hydro_88 PF07470.8 EIW75370.1 - 0.076 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 Ashwin PF15323.1 EIW75370.1 - 0.31 11.0 1.4 0.57 10.1 1.0 1.3 1 0 0 1 1 1 0 Developmental protein DEAD PF00270.24 EIW75371.1 - 6.9e-09 35.4 0.0 1.1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Dimer_Tnp_hAT PF05699.9 EIW75374.1 - 6.7e-12 44.8 0.4 7.1e-12 44.7 0.3 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Cryptochrome_C PF12546.3 EIW75376.1 - 0.057 14.1 1.4 0.098 13.3 0.9 1.5 1 1 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal Plasmid_stab_B PF10784.4 EIW75380.1 - 0.12 11.9 0.1 0.93 9.1 0.0 2.2 2 0 0 2 2 2 0 Plasmid stability protein AAA PF00004.24 EIW75382.1 - 1.4e-91 303.5 0.0 1.3e-44 151.5 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIW75382.1 - 1.1e-12 47.4 0.0 3.5e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EIW75382.1 - 2.3e-12 46.9 0.0 3.7e-06 26.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EIW75382.1 - 3.5e-12 47.2 0.1 8.7e-05 23.3 0.0 3.5 3 1 0 3 3 3 2 AAA domain AAA_2 PF07724.9 EIW75382.1 - 2.4e-11 43.8 0.0 8.3e-06 25.8 0.0 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EIW75382.1 - 7.3e-11 41.9 0.3 6.8e-05 22.6 0.1 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EIW75382.1 - 1.1e-10 41.7 0.1 0.0016 18.5 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EIW75382.1 - 1.3e-10 41.5 0.5 0.0032 17.4 0.0 3.9 3 2 1 4 4 4 2 AAA ATPase domain TIP49 PF06068.8 EIW75382.1 - 2.8e-08 32.9 0.0 0.0024 16.6 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 EIW75382.1 - 1.2e-07 31.2 1.8 0.0048 16.3 0.0 3.5 2 2 0 3 3 3 1 AAA domain IstB_IS21 PF01695.12 EIW75382.1 - 1.7e-07 30.7 0.1 0.0038 16.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EIW75382.1 - 1.9e-07 30.7 0.3 0.0068 16.1 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain RNA_helicase PF00910.17 EIW75382.1 - 4.8e-07 29.9 0.0 0.015 15.4 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Mg_chelatase PF01078.16 EIW75382.1 - 5.7e-07 28.8 0.3 0.011 14.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI CDC48_2 PF02933.12 EIW75382.1 - 8.5e-07 28.5 0.0 1.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.1 EIW75382.1 - 8.5e-07 28.9 0.0 0.038 13.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EIW75382.1 - 1.6e-06 28.2 0.0 0.092 12.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.1 EIW75382.1 - 2.2e-06 27.4 0.1 0.087 12.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 EIW75382.1 - 2.4e-06 26.8 0.0 0.025 13.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin KaiC PF06745.8 EIW75382.1 - 2.6e-06 26.7 0.9 0.65 9.0 0.0 3.5 2 1 1 3 3 3 2 KaiC AAA_18 PF13238.1 EIW75382.1 - 3.1e-06 27.5 0.1 0.028 14.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.12 EIW75382.1 - 1.2e-05 24.3 0.3 0.0096 14.8 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ABC_tran PF00005.22 EIW75382.1 - 2.1e-05 24.8 0.0 0.32 11.2 0.0 3.5 2 1 0 2 2 2 1 ABC transporter ResIII PF04851.10 EIW75382.1 - 2.3e-05 24.2 0.0 0.013 15.3 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Bac_DnaA PF00308.13 EIW75382.1 - 8.3e-05 22.3 0.0 0.7 9.5 0.0 2.8 3 1 0 3 3 3 2 Bacterial dnaA protein Sigma54_activat PF00158.21 EIW75382.1 - 0.00013 21.4 0.0 0.42 10.0 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain Arch_ATPase PF01637.13 EIW75382.1 - 0.00014 21.6 0.0 0.2 11.3 0.0 2.7 2 1 0 2 2 2 1 Archaeal ATPase AAA_11 PF13086.1 EIW75382.1 - 0.00015 21.3 0.0 0.42 10.1 0.0 2.4 2 1 0 2 2 2 2 AAA domain PhoH PF02562.11 EIW75382.1 - 0.00019 20.7 0.4 0.25 10.5 0.0 2.5 2 0 0 2 2 2 2 PhoH-like protein AAA_3 PF07726.6 EIW75382.1 - 0.00036 20.1 0.0 0.5 9.9 0.0 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EIW75382.1 - 0.00049 19.1 0.0 0.35 9.8 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.1 EIW75382.1 - 0.00065 19.7 0.0 0.81 9.7 0.0 3.0 3 0 0 3 3 2 1 Sigma-54 interaction domain DUF815 PF05673.8 EIW75382.1 - 0.0012 17.8 0.0 0.44 9.4 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF815) T2SE PF00437.15 EIW75382.1 - 0.0015 17.4 0.0 0.14 11.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein NACHT PF05729.7 EIW75382.1 - 0.003 17.2 0.1 0.6 9.7 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA_30 PF13604.1 EIW75382.1 - 0.0031 17.1 1.1 1.9 7.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain NB-ARC PF00931.17 EIW75382.1 - 0.0033 16.3 0.1 0.39 9.5 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Viral_helicase1 PF01443.13 EIW75382.1 - 0.0046 16.5 0.0 0.2 11.1 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 EIW75382.1 - 0.019 14.5 0.2 3.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 EIW75382.1 - 0.028 14.1 0.2 1.7 8.3 0.0 3.0 3 0 0 3 3 3 0 NTPase PIF1 PF05970.9 EIW75382.1 - 0.064 12.1 0.3 6.8 5.5 0.0 3.4 4 0 0 4 4 4 0 PIF1-like helicase IPT PF01745.11 EIW75382.1 - 0.091 11.9 0.1 6.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase ATP-synt_ab PF00006.20 EIW75382.1 - 0.18 11.2 0.0 3.5 7.0 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain HEAT_EZ PF13513.1 EIW75384.1 - 0.036 14.5 0.0 3.1 8.3 0.0 3.1 3 0 0 3 3 3 0 HEAT-like repeat ATG16 PF08614.6 EIW75388.1 - 0.016 15.0 1.9 0.02 14.7 1.3 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Iron_permease PF04120.7 EIW75388.1 - 0.054 13.0 0.2 0.078 12.5 0.1 1.2 1 0 0 1 1 1 0 Low affinity iron permease DUF4510 PF14971.1 EIW75388.1 - 0.57 10.3 8.6 1.2 9.2 6.0 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4510) NST1 PF13945.1 EIW75388.1 - 5.5 7.0 10.4 5.1 7.1 6.4 1.5 1 1 0 1 1 1 0 Salt tolerance down-regulator Cu-oxidase PF00394.17 EIW75389.1 - 9.1e-47 158.9 0.2 1.9e-42 144.8 0.0 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIW75389.1 - 5.7e-38 129.5 2.8 1.3e-32 112.2 0.3 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIW75389.1 - 4.4e-37 126.4 0.4 4.4e-37 126.4 0.3 3.1 3 1 0 3 3 3 1 Multicopper oxidase LRR_5 PF13306.1 EIW75390.1 - 0.024 14.3 0.8 0.04 13.6 0.6 1.6 1 1 0 1 1 1 0 Leucine rich repeats (6 copies) DUF4476 PF14771.1 EIW75390.1 - 0.025 14.6 1.4 2.3 8.2 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4476) UPF0126 PF03458.8 EIW75390.1 - 2.8 7.6 10.7 2.7 7.6 0.5 3.7 2 1 2 4 4 4 0 UPF0126 domain DDE_3 PF13358.1 EIW75391.1 - 7.9e-09 35.4 0.0 7.5e-06 25.7 0.0 2.7 2 1 0 2 2 2 2 DDE superfamily endonuclease HTH_29 PF13551.1 EIW75391.1 - 0.074 13.2 0.2 0.22 11.6 0.1 1.8 1 0 0 1 1 1 0 Winged helix-turn helix GST_N_3 PF13417.1 EIW75392.1 - 7.9e-14 51.6 0.0 3.7e-13 49.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW75392.1 - 8.9e-10 38.4 0.0 6.8e-09 35.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW75392.1 - 1.6e-06 28.1 0.0 4.2e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW75392.1 - 3e-06 27.0 0.1 9.5e-06 25.4 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW75392.1 - 0.0034 17.3 0.0 0.0071 16.3 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW75392.1 - 0.038 14.4 0.0 0.32 11.4 0.0 2.1 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain FHA PF00498.21 EIW75393.1 - 3.1e-15 56.0 0.0 6.1e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EIW75393.1 - 1e-09 38.0 8.9 1.7e-09 37.3 6.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIW75393.1 - 5.2e-06 26.0 8.5 8e-06 25.4 5.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EIW75393.1 - 2e-05 24.5 6.3 4.8e-05 23.3 4.4 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EIW75393.1 - 6.8e-05 22.6 1.5 0.00011 21.9 1.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EIW75393.1 - 0.0016 18.4 9.5 0.0025 17.8 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW75393.1 - 0.002 17.8 7.3 0.0035 17.0 5.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIW75393.1 - 0.0021 17.7 5.8 0.0033 17.0 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EIW75393.1 - 0.004 16.8 4.6 0.0071 16.0 3.2 1.4 1 0 0 1 1 1 1 PHD-finger zf-UDP PF14569.1 EIW75393.1 - 0.035 13.8 1.2 0.065 12.9 0.8 1.4 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.1 EIW75393.1 - 0.069 13.0 5.5 0.14 12.0 3.8 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF2422 PF10337.4 EIW75394.1 - 5.8e-79 266.0 0.2 1.2e-78 264.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EIW75394.1 - 2.8e-30 105.6 0.0 1.2e-29 103.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 EIW75394.1 - 1.3e-10 41.2 14.5 1.3e-10 41.2 10.0 3.4 3 0 0 3 3 3 1 Fusaric acid resistance protein-like DUF1049 PF06305.6 EIW75394.1 - 1.9 8.0 5.8 0.51 9.8 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Abhydrolase_6 PF12697.2 EIW75395.1 - 1.6e-19 70.6 0.0 2e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW75395.1 - 1.1e-06 28.4 0.0 2.3e-06 27.4 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIW75395.1 - 0.0028 17.4 0.0 0.0062 16.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase FSH1 PF03959.8 EIW75395.1 - 0.0075 15.7 0.0 0.042 13.3 0.0 2.0 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 EIW75395.1 - 0.027 14.0 0.0 0.038 13.5 0.0 1.5 1 1 0 1 1 1 0 alpha/beta hydrolase fold Esterase PF00756.15 EIW75395.1 - 0.044 13.2 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF676 PF05057.9 EIW75395.1 - 0.16 11.2 0.0 1.6 7.9 0.0 2.0 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EIW75396.1 - 2e-23 83.4 0.6 2.4e-23 83.1 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW75396.1 - 9.3e-12 44.9 0.0 1.1e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIW75396.1 - 9.6e-08 31.7 0.1 1.9e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EIW75396.1 - 6.2e-05 22.6 0.0 0.0038 16.8 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold FSH1 PF03959.8 EIW75396.1 - 0.053 12.9 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DLH PF01738.13 EIW75396.1 - 0.065 12.5 0.1 0.41 9.8 0.0 1.9 1 1 1 2 2 2 0 Dienelactone hydrolase family Chlorophyllase2 PF12740.2 EIW75396.1 - 0.081 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 EIW75396.1 - 0.083 11.6 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase Abhydrolase_6 PF12697.2 EIW75397.1 - 1.2e-19 71.1 0.1 1.4e-19 70.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW75397.1 - 1.1e-09 38.1 0.0 1.5e-09 37.7 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EIW75397.1 - 5.6e-06 26.1 0.0 8.9e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 EIW75397.1 - 2.2e-05 24.2 0.0 3.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EIW75397.1 - 4.5e-05 23.1 0.1 0.0012 18.4 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EIW75397.1 - 0.00017 21.8 0.0 0.00026 21.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.15 EIW75397.1 - 0.014 14.8 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 EIW75397.1 - 0.14 11.7 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) FSH1 PF03959.8 EIW75397.1 - 0.19 11.1 0.0 0.71 9.2 0.0 1.8 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EIW75398.1 - 1.1e-23 84.3 0.4 1.5e-23 83.9 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW75398.1 - 6.1e-13 48.7 0.0 8.7e-13 48.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIW75398.1 - 0.00025 20.8 0.0 0.00062 19.5 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EIW75398.1 - 0.00076 19.0 0.0 0.0033 17.0 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 EIW75398.1 - 0.018 14.4 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Chlorophyllase2 PF12740.2 EIW75398.1 - 0.031 13.1 0.0 0.044 12.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme GST_N_3 PF13417.1 EIW75400.1 - 7.3e-11 42.1 0.0 1.2e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW75400.1 - 2.9e-05 23.8 0.4 5.1e-05 23.0 0.3 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW75400.1 - 6.9e-05 22.7 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW75400.1 - 0.0011 18.8 0.0 0.0023 17.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW75400.1 - 0.0021 18.5 0.1 0.0038 17.6 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Transposase_21 PF02992.9 EIW75401.1 - 1.3e-07 30.9 0.0 2.2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EIW75401.1 - 0.00019 20.9 0.0 0.0004 19.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) zf-HC2 PF13490.1 EIW75401.1 - 0.47 10.4 3.1 0.95 9.4 0.9 2.3 2 0 0 2 2 2 0 Putative zinc-finger HTHP PF11534.3 EIW75403.1 - 0.058 13.4 0.4 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 Hexameric tyrosine-coordinated heme protein (HTHP) GST_N_3 PF13417.1 EIW75404.1 - 9.5e-11 41.7 0.0 2e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW75404.1 - 6.1e-06 26.0 1.7 3.6e-05 23.5 0.5 2.5 1 1 1 2 2 2 2 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW75404.1 - 6.5e-06 26.0 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW75404.1 - 8.1e-05 22.7 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW75404.1 - 0.052 13.5 0.0 0.14 12.1 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DUF4420 PF14390.1 EIW75404.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4420) GST_C_2 PF13410.1 EIW75405.1 - 1.3e-10 40.9 0.1 3.2e-10 39.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIW75405.1 - 4.2e-08 33.2 0.0 9.2e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW75405.1 - 8e-05 22.5 0.0 0.0002 21.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW75405.1 - 0.00065 20.1 0.0 0.00099 19.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW75405.1 - 0.0027 17.6 0.0 0.0049 16.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW75405.1 - 0.0031 17.6 0.0 0.0079 16.3 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PTR2 PF00854.16 EIW75406.1 - 2.1e-44 151.8 18.8 1.3e-42 145.9 12.8 3.3 2 1 0 2 2 2 1 POT family MTP18 PF10558.4 EIW75406.1 - 0.012 15.4 0.0 0.032 14.0 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) GST_N_3 PF13417.1 EIW75407.1 - 1.3e-13 50.9 0.0 2.3e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW75407.1 - 3.2e-08 33.4 0.0 5.2e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW75407.1 - 5.5e-05 23.2 0.0 0.00023 21.2 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW75407.1 - 0.00028 20.7 0.2 0.00054 19.7 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW75407.1 - 0.0081 16.1 0.1 0.018 15.0 0.1 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EIW75407.1 - 0.11 12.4 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin GST_C_3 PF14497.1 EIW75407.1 - 0.12 12.8 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIW75408.1 - 7.7e-13 48.4 0.0 1.3e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW75408.1 - 1.6e-07 31.0 0.4 4.9e-07 29.5 0.3 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW75408.1 - 4.5e-07 29.7 0.0 7.7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW75408.1 - 2e-05 24.6 0.0 4.6e-05 23.5 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW75408.1 - 0.0024 17.8 0.0 0.0053 16.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW75408.1 - 0.058 13.8 0.0 0.088 13.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIW75409.1 - 2.6e-12 46.7 0.0 4.7e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW75409.1 - 1.4e-06 28.1 0.0 2.2e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW75409.1 - 2.8e-05 24.1 0.0 7.5e-05 22.8 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW75409.1 - 0.00046 20.0 0.1 0.00092 19.0 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW75409.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIW75410.1 - 9.3e-12 45.0 0.0 1.8e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW75410.1 - 3.7e-08 33.1 0.9 1.6e-07 31.1 0.3 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW75410.1 - 5.1e-06 26.3 0.0 8.4e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW75410.1 - 4.5e-05 23.5 0.0 0.00014 21.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW75410.1 - 0.00047 20.0 0.0 0.0013 18.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW75410.1 - 0.031 14.7 0.1 0.064 13.7 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIW75411.1 - 5.4e-13 48.9 0.0 9.5e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW75411.1 - 3.3e-06 26.9 0.0 5.4e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW75411.1 - 3.8e-06 26.9 0.0 9.6e-06 25.6 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW75411.1 - 0.00061 19.6 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW75411.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Zn_clus PF00172.13 EIW75412.1 - 0.00042 20.1 7.5 0.00084 19.1 5.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Granulin PF00396.13 EIW75413.1 - 0.014 15.4 11.0 0.014 15.4 7.6 4.6 1 1 4 5 5 5 0 Granulin Fer2_3 PF13085.1 EIW75414.1 - 1.8e-32 111.4 0.0 2.8e-32 110.8 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EIW75414.1 - 7.4e-11 42.2 7.7 7.4e-11 42.2 5.3 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EIW75414.1 - 1.7e-08 34.3 5.4 1.7e-08 34.3 3.8 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EIW75414.1 - 6.6e-05 22.6 5.1 6.6e-05 22.6 3.5 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EIW75414.1 - 0.00011 22.3 4.4 0.038 14.2 0.4 3.0 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 EIW75414.1 - 0.00011 22.5 2.6 0.00011 22.5 1.8 2.6 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.2 EIW75414.1 - 0.00042 20.6 4.4 0.00042 20.6 3.0 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.22 EIW75414.1 - 0.0015 18.2 3.7 0.0028 17.3 0.3 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_15 PF13459.1 EIW75414.1 - 0.32 11.5 6.8 1.3 9.6 0.1 2.7 3 0 0 3 3 3 0 4Fe-4S single cluster domain Abhydrolase_6 PF12697.2 EIW75416.1 - 9.2e-21 74.7 2.8 1.1e-20 74.5 1.9 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW75416.1 - 1.3e-10 41.1 0.0 1.4e-10 41.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIW75416.1 - 3.4e-09 36.4 0.0 6.4e-09 35.5 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 EIW75416.1 - 0.0017 17.6 0.0 0.038 13.2 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family ATG13 PF10033.4 EIW75418.1 - 1.7e-28 99.6 0.0 2.8e-27 95.6 0.0 2.1 1 1 0 1 1 1 1 Autophagy-related protein 13 Transaldolase PF00923.14 EIW75419.1 - 1.7e-95 319.4 0.0 2e-95 319.2 0.0 1.0 1 0 0 1 1 1 1 Transaldolase Abhydrolase_6 PF12697.2 EIW75420.1 - 1.4e-24 87.2 3.0 1.8e-24 86.8 2.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW75420.1 - 2.8e-11 43.3 0.0 4e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIW75420.1 - 6.5e-08 32.3 0.0 1.7e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EIW75420.1 - 0.0028 17.2 0.0 0.021 14.4 0.0 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 EIW75420.1 - 0.054 12.8 0.0 0.095 12.0 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EIW75425.1 - 6.4e-20 72.0 5.5 7.5e-20 71.7 3.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW75425.1 - 1.4e-10 41.0 0.0 1.7e-10 40.8 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIW75425.1 - 8.8e-09 35.1 0.0 1.6e-08 34.2 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DLH PF01738.13 EIW75425.1 - 0.12 11.6 0.0 0.45 9.7 0.0 1.8 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 EIW75427.1 - 5.3e-30 104.9 2.8 6.1e-30 104.7 1.9 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW75427.1 - 1e-16 60.9 0.0 1.3e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIW75427.1 - 2.5e-10 40.0 0.0 3.5e-09 36.3 0.0 2.5 3 0 0 3 3 3 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EIW75427.1 - 8.9e-09 35.2 0.0 1.1e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EIW75427.1 - 0.001 19.3 0.0 0.0014 18.8 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain FSH1 PF03959.8 EIW75427.1 - 0.0021 17.5 0.0 0.0038 16.6 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Ser_hydrolase PF06821.8 EIW75427.1 - 0.0035 16.9 0.0 0.0088 15.6 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase Chlorophyllase2 PF12740.2 EIW75427.1 - 0.025 13.4 0.2 0.22 10.3 0.1 2.0 1 1 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.15 EIW75427.1 - 0.028 13.8 0.1 0.055 12.8 0.0 1.6 1 1 1 2 2 2 0 Putative esterase PGAP1 PF07819.8 EIW75427.1 - 0.077 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Patatin PF01734.17 EIW75427.1 - 0.13 12.2 0.1 0.27 11.1 0.1 1.4 1 1 0 1 1 1 0 Patatin-like phospholipase Chlorophyllase PF07224.6 EIW75427.1 - 0.15 10.8 0.1 0.42 9.3 0.1 1.7 1 1 0 1 1 1 0 Chlorophyllase Spc24 PF08286.6 EIW75428.1 - 1.2 8.8 5.7 37 4.0 0.0 2.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Abhydrolase_6 PF12697.2 EIW75429.1 - 1.7e-15 57.5 1.9 6e-15 55.7 1.3 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW75429.1 - 3.4e-09 36.6 0.0 4.5e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIW75429.1 - 3.9e-07 29.8 0.0 8.5e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 EIW75430.1 - 2.3e-20 73.4 3.8 5.7e-20 72.1 2.6 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW75430.1 - 1.2e-11 44.5 0.5 2.1e-11 43.7 0.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIW75430.1 - 4.8e-08 32.7 0.0 1.4e-07 31.2 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EIW75430.1 - 0.00075 19.1 0.1 0.006 16.1 0.0 2.2 1 1 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 EIW75430.1 - 0.026 13.4 0.2 0.17 10.7 0.1 2.0 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydro_lipase PF04083.11 EIW75430.1 - 0.076 12.3 0.0 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region PGAP1 PF07819.8 EIW75430.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.9 EIW75430.1 - 0.16 11.2 0.1 0.5 9.6 0.0 1.7 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EIW75431.1 - 3e-24 86.1 1.9 3.5e-24 85.9 1.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW75431.1 - 2.8e-11 43.3 0.0 5.2e-11 42.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIW75431.1 - 1.2e-06 28.2 0.0 3e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EIW75431.1 - 0.0089 15.6 0.2 0.21 11.1 0.2 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EIW75431.1 - 0.01 16.0 0.0 0.014 15.5 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.8 EIW75431.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein SKG6 PF08693.5 EIW75432.1 - 0.00015 20.9 1.6 0.00032 19.9 1.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Herpes_gE PF02480.11 EIW75432.1 - 0.0063 14.8 0.0 0.0086 14.3 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E BatD PF13584.1 EIW75432.1 - 0.008 14.8 0.0 0.011 14.3 0.0 1.1 1 0 0 1 1 1 1 Oxygen tolerance Herpes_gE PF02480.11 EIW75433.1 - 0.012 13.8 0.1 0.016 13.5 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Polysacc_synt_C PF14667.1 EIW75433.1 - 0.027 14.2 0.2 0.039 13.7 0.2 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain DUF3609 PF12259.3 EIW75433.1 - 0.028 13.1 0.0 0.035 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) EphA2_TM PF14575.1 EIW75433.1 - 0.049 14.0 0.0 0.074 13.4 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4381 PF14316.1 EIW75433.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) 7tm_7 PF08395.7 EIW75433.1 - 0.11 11.5 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor Herpes_gE PF02480.11 EIW75434.1 - 7.4e-05 21.1 4.9 0.013 13.7 0.0 2.9 2 1 1 3 3 3 2 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 EIW75434.1 - 8.5e-05 22.8 0.2 0.74 10.2 0.1 2.5 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 EIW75434.1 - 8.6e-05 21.9 1.5 0.031 13.8 0.0 2.5 2 0 0 2 2 2 2 Adenovirus E3 region protein CR2 TMEM154 PF15102.1 EIW75434.1 - 0.00085 19.0 2.5 0.19 11.4 0.0 2.8 2 1 0 2 2 2 1 TMEM154 protein family DUF4328 PF14219.1 EIW75434.1 - 0.0013 18.0 0.2 0.049 12.9 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4328) Syndecan PF01034.15 EIW75434.1 - 0.0014 18.2 0.6 0.039 13.5 0.0 2.4 2 0 0 2 2 2 1 Syndecan domain BatA PF07584.6 EIW75434.1 - 0.0023 18.0 0.5 1.6 8.9 0.0 2.3 2 0 0 2 2 2 1 Aerotolerance regulator N-terminal Rifin_STEVOR PF02009.11 EIW75434.1 - 0.0036 16.9 0.0 0.8 9.2 0.0 2.1 2 0 0 2 2 2 1 Rifin/stevor family DUF1191 PF06697.7 EIW75434.1 - 0.0076 15.0 0.1 1.9 7.1 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1191) Colicin_V PF02674.11 EIW75434.1 - 0.0091 15.8 0.6 3.1 7.6 0.3 2.3 2 0 0 2 2 2 1 Colicin V production protein PepSY_TM_2 PF13703.1 EIW75434.1 - 0.012 15.8 1.4 2.5 8.3 0.2 2.4 2 0 0 2 2 2 0 PepSY-associated TM helix SKG6 PF08693.5 EIW75434.1 - 0.03 13.6 1.0 0.03 13.6 0.7 2.9 2 1 0 2 2 2 0 Transmembrane alpha-helix domain YajC PF02699.10 EIW75434.1 - 0.032 13.8 0.1 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Preprotein translocase subunit Yip1 PF04893.12 EIW75434.1 - 0.049 13.1 2.4 0.31 10.5 0.5 2.2 2 0 0 2 2 2 0 Yip1 domain stn_TNFRSF12A PF12191.3 EIW75434.1 - 0.05 13.6 0.6 3.4 7.7 0.1 2.6 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain BatD PF13584.1 EIW75434.1 - 0.067 11.7 0.0 4.5 5.7 0.0 2.1 2 0 0 2 2 2 0 Oxygen tolerance DUF4381 PF14316.1 EIW75434.1 - 0.078 13.0 2.1 4.5 7.3 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Plasmodium_Vir PF05795.6 EIW75434.1 - 0.087 12.0 0.8 0.27 10.3 0.0 2.0 2 1 0 2 2 2 0 Plasmodium vivax Vir protein Gly-zipper_Omp PF13488.1 EIW75434.1 - 0.096 12.3 11.2 0.85 9.3 0.6 3.1 3 0 0 3 3 3 0 Glycine zipper RCR PF12273.3 EIW75434.1 - 0.17 12.4 6.2 3.6 8.1 0.7 3.0 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Gly-zipper_OmpA PF13436.1 EIW75434.1 - 0.2 11.3 1.5 7.3 6.2 0.2 2.7 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Transgly_assoc PF04226.8 EIW75434.1 - 0.35 10.9 13.4 0.26 11.3 0.2 3.4 3 0 0 3 3 3 0 Transglycosylase associated protein DUF2937 PF11157.3 EIW75434.1 - 0.59 9.4 2.2 6.3 6.1 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF202 PF02656.10 EIW75434.1 - 0.64 10.2 4.1 22 5.3 0.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF202) Bacteriocin_IIc PF10439.4 EIW75434.1 - 0.75 9.9 4.8 5 7.3 0.1 2.7 3 0 0 3 3 3 0 Bacteriocin class II with double-glycine leader peptide Rick_17kDa_Anti PF05433.10 EIW75434.1 - 0.96 9.1 14.0 0.62 9.7 0.2 2.8 3 0 0 3 3 3 0 Glycine zipper 2TM domain PDGLE PF13190.1 EIW75434.1 - 0.97 9.1 4.1 4 7.1 0.1 2.5 2 0 0 2 2 2 0 PDGLE domain DUF347 PF03988.7 EIW75434.1 - 1.2 9.0 7.5 5.1 7.0 0.1 3.3 4 0 0 4 4 3 0 Repeat of Unknown Function (DUF347) DUF2273 PF10031.4 EIW75434.1 - 2 8.0 8.1 4.5 6.9 1.1 2.3 2 0 0 2 2 2 0 Small integral membrane protein (DUF2273) Gly-zipper_YMGG PF13441.1 EIW75434.1 - 2.1 7.9 10.9 2.2 7.8 0.6 2.8 3 0 0 3 3 3 0 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 EIW75435.1 - 0.32 10.6 3.6 0.15 11.6 0.8 1.6 2 0 0 2 2 2 0 Glycine zipper Methyltransf_11 PF08241.7 EIW75436.1 - 7.1e-19 68.1 0.0 1.2e-18 67.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW75436.1 - 3.1e-12 47.0 0.0 8.8e-12 45.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW75436.1 - 5.3e-12 45.5 0.0 8.3e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW75436.1 - 1e-11 45.0 0.0 1.7e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW75436.1 - 2.3e-11 44.0 0.0 3.6e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW75436.1 - 6.1e-09 35.7 0.0 8.3e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW75436.1 - 2e-08 33.6 0.0 3e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EIW75436.1 - 3.3e-05 23.8 0.0 8.3e-05 22.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW75436.1 - 0.0012 18.2 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 EIW75436.1 - 0.037 13.6 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Methyltransf_8 PF05148.10 EIW75436.1 - 0.064 12.8 0.0 0.4 10.2 0.0 1.9 1 1 0 1 1 1 0 Hypothetical methyltransferase Oxidored_FMN PF00724.15 EIW75437.1 - 2.6e-95 319.3 0.0 3e-95 319.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 EIW75438.1 - 2.4e-96 322.6 0.0 2.8e-96 322.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Oxidored_FMN PF00724.15 EIW75439.1 - 3.7e-93 312.2 0.0 4.2e-93 312.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family NAD_binding_6 PF08030.7 EIW75440.1 - 7.8e-24 84.3 0.0 1.2e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EIW75440.1 - 4.9e-17 61.7 0.0 2e-15 56.5 0.0 2.4 1 1 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EIW75440.1 - 4.8e-15 55.7 7.1 4.8e-15 55.7 4.9 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EIW75440.1 - 0.045 14.3 0.0 0.25 11.9 0.0 2.1 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain adh_short PF00106.20 EIW75441.1 - 1.6e-25 89.9 0.1 2.5e-25 89.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW75441.1 - 2.1e-13 50.6 0.0 2.7e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EIW75441.1 - 6.5e-07 28.7 0.0 8.8e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 EIW75441.1 - 2.4e-05 24.0 0.2 7e-05 22.5 0.1 1.6 1 1 0 1 1 1 1 KR domain PAE PF03283.8 EIW75441.1 - 0.012 14.2 0.0 0.018 13.6 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase GST_N_3 PF13417.1 EIW75442.1 - 9.7e-09 35.3 0.1 1.8e-08 34.4 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW75442.1 - 1.1e-06 28.5 0.1 2e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW75442.1 - 0.45 10.4 2.7 0.49 10.3 0.2 2.1 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain LRR_6 PF13516.1 EIW75443.1 - 2.4e-10 39.3 17.4 1.1 9.5 0.0 8.4 8 0 0 8 8 8 5 Leucine Rich repeat LRR_4 PF12799.2 EIW75443.1 - 2.5e-10 39.7 17.4 0.00026 20.5 0.8 6.1 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIW75443.1 - 1.4e-07 30.5 10.4 8.5 6.8 0.0 9.2 9 2 1 10 10 10 2 Leucine Rich Repeat LRR_7 PF13504.1 EIW75443.1 - 0.0001 21.8 17.3 12 6.6 0.0 8.6 9 0 0 9 9 9 1 Leucine rich repeat LRR_8 PF13855.1 EIW75443.1 - 0.00068 19.3 16.3 0.0043 16.7 1.8 5.0 4 2 2 6 6 6 2 Leucine rich repeat Oxidored_FMN PF00724.15 EIW75445.1 - 8.6e-93 311.0 0.0 9.7e-93 310.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Aldedh PF00171.17 EIW75446.1 - 1.4e-182 607.1 0.9 1.6e-182 606.9 0.6 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIW75446.1 - 0.0065 15.2 0.0 0.18 10.4 0.0 2.0 2 0 0 2 2 2 2 Acyl-CoA reductase (LuxC) TRAM_LAG1_CLN8 PF03798.11 EIW75447.1 - 7.3e-08 32.1 18.9 1.1e-07 31.6 13.1 1.3 1 0 0 1 1 1 1 TLC domain Tet_JBP PF12851.2 EIW75449.1 - 3.5e-13 49.2 0.0 4.9e-13 48.7 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily CLAMP PF14769.1 EIW75450.1 - 0.084 13.0 0.0 0.17 12.0 0.0 1.5 1 1 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 Transposase_21 PF02992.9 EIW75451.1 - 1.5e-11 43.8 0.0 2.5e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF2582 PF10771.4 EIW75453.1 - 0.093 12.5 0.6 0.51 10.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2582) Filament PF00038.16 EIW75454.1 - 0.011 15.1 0.1 0.014 14.8 0.1 1.1 1 0 0 1 1 1 0 Intermediate filament protein MscS_porin PF12795.2 EIW75454.1 - 0.02 14.2 0.8 0.056 12.7 0.4 1.7 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DASH_Spc34 PF08657.5 EIW75454.1 - 0.11 12.1 0.8 0.24 11.0 0.0 1.7 1 1 1 2 2 2 0 DASH complex subunit Spc34 AAA_13 PF13166.1 EIW75454.1 - 0.12 10.8 0.1 0.15 10.4 0.0 1.0 1 0 0 1 1 1 0 AAA domain HMG_box_2 PF09011.5 EIW75458.1 - 0.022 15.1 2.4 0.022 15.1 1.7 2.2 2 1 1 3 3 3 0 HMG-box domain HMG_box PF00505.14 EIW75458.1 - 0.026 14.7 3.3 0.04 14.1 1.5 2.0 1 1 1 2 2 2 0 HMG (high mobility group) box MORN_2 PF07661.8 EIW75458.1 - 0.091 12.8 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 MORN repeat variant Tet_JBP PF12851.2 EIW75460.1 - 6e-10 38.6 0.0 7.2e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily F-box-like PF12937.2 EIW75460.1 - 0.0068 16.1 0.1 0.015 15.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like Menin PF05053.8 EIW75461.1 - 0.021 13.0 0.4 0.023 12.9 0.3 1.1 1 0 0 1 1 1 0 Menin DUF605 PF04652.11 EIW75461.1 - 0.093 12.1 5.2 0.12 11.8 3.6 1.1 1 0 0 1 1 1 0 Vta1 like DUF2408 PF10303.4 EIW75462.1 - 0.079 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) zf-B_box PF00643.19 EIW75466.1 - 0.036 13.9 5.5 0.15 11.9 3.8 2.2 1 0 0 1 1 1 0 B-box zinc finger Spt5_N PF11942.3 EIW75469.1 - 7 7.3 12.0 4.4 7.9 1.4 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Syntaxin PF00804.20 EIW75470.1 - 0.026 14.7 0.1 0.052 13.7 0.0 1.4 1 0 0 1 1 1 0 Syntaxin DUF2130 PF09903.4 EIW75470.1 - 0.056 12.1 0.1 0.081 11.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2130) DUF1759 PF03564.10 EIW75470.1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Ndc1_Nup PF09531.5 EIW75473.1 - 2.5e-38 131.9 0.0 3.2e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Methyltransf_11 PF08241.7 EIW75476.1 - 6.9e-06 26.4 0.0 1.3e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW75476.1 - 1.7e-05 24.5 0.0 2.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW75476.1 - 7.2e-05 22.0 0.0 0.0013 17.9 0.0 2.7 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EIW75476.1 - 0.00093 18.8 0.0 0.0053 16.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW75476.1 - 0.0049 17.2 0.0 0.01 16.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 EIW75477.1 - 1.6e-19 70.3 0.4 2.2e-19 69.9 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW75477.1 - 4.2e-07 29.9 0.0 6.1e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW75477.1 - 6.9e-07 29.0 0.2 9.8e-07 28.5 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW75477.1 - 0.067 12.6 0.1 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW75477.1 - 0.09 12.7 0.1 0.2 11.6 0.1 1.6 1 1 0 1 1 1 0 NADH(P)-binding Pex19 PF04614.7 EIW75478.1 - 2.7e-44 151.6 6.3 3.2e-44 151.4 4.4 1.1 1 0 0 1 1 1 1 Pex19 protein family GBP_C PF02841.9 EIW75478.1 - 0.011 14.9 3.1 1.3 8.1 0.8 2.3 2 0 0 2 2 2 0 Guanylate-binding protein, C-terminal domain NAD_binding_6 PF08030.7 EIW75479.1 - 1.4e-20 73.7 0.0 2e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EIW75479.1 - 8e-17 61.0 0.0 2.2e-16 59.6 0.0 1.8 1 1 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EIW75479.1 - 7.5e-15 55.1 5.9 7.5e-15 55.1 4.1 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component Flavodoxin_5 PF12724.2 EIW75479.1 - 0.0043 17.0 0.0 0.63 10.0 0.0 2.6 2 0 0 2 2 2 1 Flavodoxin domain NAD_binding_1 PF00175.16 EIW75479.1 - 0.074 13.6 0.0 0.3 11.6 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain adh_short PF00106.20 EIW75480.1 - 7.4e-24 84.5 0.7 1.2e-23 83.8 0.3 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW75480.1 - 1.6e-18 67.3 0.1 2.3e-08 34.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW75480.1 - 8e-10 38.6 1.3 1.3e-09 37.9 0.5 1.7 2 1 0 2 2 2 1 KR domain Prefoldin_2 PF01920.15 EIW75480.1 - 0.0017 18.1 0.2 0.0029 17.3 0.1 1.3 1 0 0 1 1 1 1 Prefoldin subunit HemX PF04375.9 EIW75480.1 - 0.0019 16.8 0.0 0.0027 16.3 0.0 1.1 1 0 0 1 1 1 1 HemX Epimerase PF01370.16 EIW75480.1 - 0.0023 17.4 0.1 0.0037 16.7 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW75480.1 - 0.0027 17.7 1.4 0.026 14.5 1.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 EIW75480.1 - 0.015 14.9 0.4 0.031 13.9 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EIW75480.1 - 0.029 13.2 0.0 0.042 12.7 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FUSC PF04632.7 EIW75481.1 - 0.17 10.2 2.4 0.34 9.2 1.7 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family p450 PF00067.17 EIW75482.1 - 3.4e-60 203.8 0.0 9.1e-60 202.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW75483.1 - 1.7e-69 234.5 0.0 3e-69 233.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 AAA PF00004.24 EIW75484.1 - 1.3e-35 122.4 0.0 5.5e-15 55.7 0.0 4.9 4 0 0 4 4 4 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.1 EIW75484.1 - 1.5e-22 80.0 0.0 4.1e-22 78.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_11 PF13086.1 EIW75484.1 - 2.6e-20 73.0 10.4 1.4e-16 60.7 0.0 5.3 5 1 0 5 5 5 2 AAA domain AAA_19 PF13245.1 EIW75484.1 - 5.5e-16 58.0 2.1 1.3e-07 31.2 0.1 4.1 3 0 0 3 3 3 3 Part of AAA domain AAA_16 PF13191.1 EIW75484.1 - 1.4e-11 44.6 0.4 2.5e-06 27.6 0.1 4.3 3 0 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EIW75484.1 - 2.3e-11 44.5 0.6 0.01 16.6 0.0 4.4 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EIW75484.1 - 3.3e-11 43.4 8.4 0.0031 17.6 0.0 7.5 5 3 0 6 6 6 2 AAA domain AAA_30 PF13604.1 EIW75484.1 - 2.2e-10 40.4 6.6 2e-06 27.5 0.0 5.3 5 1 1 6 6 5 2 AAA domain AAA_33 PF13671.1 EIW75484.1 - 5.4e-08 32.8 3.4 0.22 11.3 0.0 4.9 4 0 0 4 4 4 3 AAA domain AAA_5 PF07728.9 EIW75484.1 - 2.2e-07 30.6 0.3 0.46 10.1 0.0 4.6 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EIW75484.1 - 3.7e-07 29.7 0.1 2.3 7.6 0.0 4.8 5 0 0 5 5 5 2 IstB-like ATP binding protein ResIII PF04851.10 EIW75484.1 - 9.7e-07 28.7 0.0 0.0066 16.2 0.0 4.4 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Mg_chelatase PF01078.16 EIW75484.1 - 1e-06 28.0 0.0 0.41 9.7 0.0 4.1 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EIW75484.1 - 2.2e-06 27.2 0.5 1.4 8.3 0.0 4.8 4 1 0 4 4 4 2 Sigma-54 interaction domain AAA_18 PF13238.1 EIW75484.1 - 2.5e-06 27.8 7.0 0.27 11.5 0.0 5.1 4 0 0 4 4 4 2 AAA domain DUF2075 PF09848.4 EIW75484.1 - 1.3e-05 24.3 2.7 0.038 12.9 0.0 5.6 6 1 0 6 6 6 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EIW75484.1 - 2.6e-05 24.3 0.0 0.35 11.0 0.0 3.7 3 0 0 3 3 3 1 RNA helicase AAA_14 PF13173.1 EIW75484.1 - 0.00053 19.9 0.0 0.36 10.7 0.0 3.8 4 1 0 4 4 3 1 AAA domain AAA_24 PF13479.1 EIW75484.1 - 0.00088 18.9 2.2 2.1 7.8 0.3 3.8 3 0 0 3 3 3 1 AAA domain DEAD PF00270.24 EIW75484.1 - 0.0015 18.0 0.6 0.085 12.3 0.0 3.2 3 0 0 3 3 3 1 DEAD/DEAH box helicase PhoH PF02562.11 EIW75484.1 - 0.0026 17.0 0.0 4.5 6.4 0.0 3.4 3 0 0 3 3 3 1 PhoH-like protein Torsin PF06309.6 EIW75484.1 - 0.0038 17.1 0.0 7.4 6.4 0.0 3.5 3 0 0 3 3 3 0 Torsin AAA_28 PF13521.1 EIW75484.1 - 0.0042 17.0 8.2 1 9.2 0.0 5.0 5 0 0 5 5 4 1 AAA domain SRP54 PF00448.17 EIW75484.1 - 0.0087 15.5 0.3 0.72 9.2 0.0 3.1 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain NACHT PF05729.7 EIW75484.1 - 0.0098 15.5 1.6 2.3 7.8 0.0 4.0 4 0 0 4 4 3 1 NACHT domain Guanylate_cyc_2 PF09778.4 EIW75484.1 - 0.013 14.6 0.0 0.38 9.8 0.0 2.4 2 0 0 2 2 2 0 Guanylylate cyclase KaiC PF06745.8 EIW75484.1 - 0.048 12.7 0.6 8.6 5.4 0.0 3.2 3 0 0 3 3 3 0 KaiC LRV_FeS PF05484.6 EIW75484.1 - 0.065 12.8 1.3 6.8 6.3 0.0 3.2 3 0 0 3 3 3 0 LRV protein FeS4 cluster MobB PF03205.9 EIW75484.1 - 0.089 12.4 1.7 36 4.0 0.0 3.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EIW75484.1 - 0.1 11.9 7.4 4.1 6.7 0.0 4.2 4 0 0 4 4 3 0 AAA domain Zot PF05707.7 EIW75484.1 - 0.14 11.6 0.9 22 4.4 0.0 4.0 5 0 0 5 5 4 0 Zonular occludens toxin (Zot) AAA_10 PF12846.2 EIW75484.1 - 0.33 10.3 4.2 14 4.9 0.1 4.5 4 1 1 5 5 5 0 AAA-like domain AAA PF00004.24 EIW75485.1 - 3e-43 147.1 0.0 1e-14 54.8 0.0 4.9 4 0 0 4 4 4 4 ATPase family associated with various cellular activities (AAA) AAA_12 PF13087.1 EIW75485.1 - 1.8e-38 131.9 0.0 6.2e-38 130.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIW75485.1 - 7.7e-29 100.9 19.8 4.9e-23 81.9 0.0 6.8 5 1 0 5 5 5 2 AAA domain AAA_19 PF13245.1 EIW75485.1 - 7.9e-22 76.8 2.6 1.6e-06 27.7 0.0 5.0 4 0 0 4 4 4 4 Part of AAA domain AAA_22 PF13401.1 EIW75485.1 - 2.4e-16 60.0 4.4 0.004 17.3 0.0 6.8 5 3 0 5 5 4 4 AAA domain AAA_30 PF13604.1 EIW75485.1 - 7.8e-15 54.9 14.7 6.6e-06 25.8 0.0 7.0 6 1 0 6 6 6 5 AAA domain AAA_5 PF07728.9 EIW75485.1 - 1.2e-14 54.2 0.7 0.0041 16.8 0.0 4.8 4 0 0 4 4 4 4 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EIW75485.1 - 1.7e-13 51.4 14.6 0.017 15.9 0.0 6.4 6 0 0 6 6 4 4 AAA domain Mg_chelatase PF01078.16 EIW75485.1 - 5.1e-12 45.3 0.1 0.11 11.6 0.0 4.9 4 1 0 4 4 4 4 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EIW75485.1 - 3.9e-09 36.1 2.7 0.089 12.2 0.0 4.9 5 0 0 5 5 4 3 IstB-like ATP binding protein AAA_16 PF13191.1 EIW75485.1 - 1.1e-08 35.3 23.2 0.0011 19.0 0.0 6.3 6 1 0 6 6 4 3 AAA ATPase domain RNA_helicase PF00910.17 EIW75485.1 - 1.6e-08 34.6 0.1 2.1 8.5 0.0 5.0 4 0 0 4 4 4 1 RNA helicase Sigma54_activat PF00158.21 EIW75485.1 - 3.8e-08 32.9 0.8 0.73 9.2 0.0 5.2 5 1 0 5 5 5 2 Sigma-54 interaction domain DUF2075 PF09848.4 EIW75485.1 - 7e-08 31.8 5.9 0.0018 17.2 0.0 6.2 5 1 0 5 5 5 1 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 EIW75485.1 - 3.9e-07 30.0 7.2 0.9 9.4 0.0 5.3 5 0 0 5 5 4 3 AAA domain AAA_25 PF13481.1 EIW75485.1 - 1.9e-05 24.1 0.9 0.49 9.7 0.0 4.7 4 0 0 4 4 4 1 AAA domain Torsin PF06309.6 EIW75485.1 - 4.5e-05 23.3 0.1 31 4.4 0.0 4.5 4 0 0 4 4 4 0 Torsin AAA_28 PF13521.1 EIW75485.1 - 5.5e-05 23.1 13.8 1.1 9.1 0.0 5.7 5 0 0 5 5 4 3 AAA domain AAA_18 PF13238.1 EIW75485.1 - 9.8e-05 22.6 22.4 1 9.7 0.1 6.0 6 0 0 6 6 4 4 AAA domain Sigma54_activ_2 PF14532.1 EIW75485.1 - 0.0001 22.3 0.6 0.18 11.8 0.0 4.7 5 0 0 5 5 4 1 Sigma-54 interaction domain PhoH PF02562.11 EIW75485.1 - 0.00033 19.9 2.6 3.3 6.8 0.1 4.3 4 0 0 4 4 4 1 PhoH-like protein ABC_tran PF00005.22 EIW75485.1 - 0.00086 19.6 7.8 12 6.1 0.0 6.0 6 0 0 6 6 5 0 ABC transporter AAA_24 PF13479.1 EIW75485.1 - 0.001 18.6 13.2 1 8.8 0.0 5.7 6 0 0 6 6 5 2 AAA domain ADK PF00406.17 EIW75485.1 - 0.002 18.0 1.0 16 5.3 0.0 4.9 4 0 0 4 4 4 0 Adenylate kinase SRP54 PF00448.17 EIW75485.1 - 0.0023 17.4 2.3 2.5 7.5 0.0 4.2 4 0 0 4 4 4 1 SRP54-type protein, GTPase domain NACHT PF05729.7 EIW75485.1 - 0.0082 15.8 2.2 32 4.1 0.0 4.4 4 0 0 4 4 4 0 NACHT domain Guanylate_cyc_2 PF09778.4 EIW75485.1 - 0.012 14.7 0.0 3.5 6.7 0.0 3.0 3 0 0 3 3 3 0 Guanylylate cyclase KaiC PF06745.8 EIW75485.1 - 0.019 14.0 3.8 6.7 5.7 0.0 4.4 5 0 0 5 5 4 0 KaiC AAA_10 PF12846.2 EIW75485.1 - 0.029 13.8 9.1 9.4 5.5 0.0 6.1 5 2 1 6 6 6 0 AAA-like domain NTPase_1 PF03266.10 EIW75485.1 - 0.12 12.0 5.0 22 4.7 0.0 4.2 4 0 0 4 4 4 0 NTPase APG6 PF04111.7 EIW75485.1 - 5.8 5.8 33.3 0.16 11.0 7.9 2.5 2 0 0 2 2 2 0 Autophagy protein Apg6 Mito_carr PF00153.22 EIW75486.1 - 1.1e-49 166.0 1.6 4.8e-18 64.6 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein E1-E2_ATPase PF00122.15 EIW75489.1 - 6e-15 54.9 0.1 6e-15 54.9 0.1 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EIW75489.1 - 8.6e-14 52.4 0.3 1.4e-11 45.1 0.2 3.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIW75489.1 - 5.6e-13 48.6 0.0 1.2e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EIW75489.1 - 2.3e-12 47.5 0.0 5.6e-11 42.9 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIW75489.1 - 0.0084 15.7 0.0 0.041 13.4 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Redoxin PF08534.5 EIW75490.1 - 8.4e-40 135.6 0.0 9.8e-40 135.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EIW75490.1 - 1.1e-13 50.9 0.0 1.2e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family STE3 PF02076.10 EIW75492.1 - 3.1e-34 118.3 16.5 3.5e-34 118.1 11.4 1.0 1 0 0 1 1 1 1 Pheromone A receptor RRM_1 PF00076.17 EIW75494.1 - 3.6e-55 183.5 0.0 5e-15 54.8 0.0 6.6 6 0 0 6 6 6 6 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW75494.1 - 1.1e-40 137.4 0.0 1.5e-08 34.5 0.0 6.6 6 0 0 6 6 6 6 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW75494.1 - 4.2e-12 45.7 0.0 0.32 10.8 0.0 6.0 6 0 0 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peripla_BP_6 PF13458.1 EIW75494.1 - 0.02 14.2 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein AA_permease_2 PF13520.1 EIW75496.1 - 2.7e-60 204.0 54.8 3.5e-60 203.7 38.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIW75496.1 - 8.4e-16 57.3 50.0 1.8e-15 56.3 34.7 1.5 1 1 0 1 1 1 1 Amino acid permease COX7B PF05392.6 EIW75496.1 - 0.11 12.1 0.2 0.45 10.1 0.2 2.0 1 0 0 1 1 1 0 Cytochrome C oxidase chain VIIB Pil1 PF13805.1 EIW75499.1 - 3.6e-14 52.5 0.0 7.7e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 Eisosome component PIL1 IFT57 PF10498.4 EIW75499.1 - 0.028 13.1 0.3 0.043 12.5 0.2 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Phage_Nu1 PF07471.7 EIW75499.1 - 0.14 11.6 1.2 0.25 10.7 0.8 1.3 1 0 0 1 1 1 0 Phage DNA packaging protein Nu1 Fib_alpha PF08702.5 EIW75499.1 - 0.32 11.1 0.7 0.64 10.1 0.5 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Seryl_tRNA_N PF02403.17 EIW75499.1 - 0.36 10.8 4.1 0.72 9.8 2.9 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain DUF1202 PF06717.6 EIW75499.1 - 0.37 10.0 0.1 0.61 9.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) GAS PF13851.1 EIW75499.1 - 1.3 8.1 6.0 2 7.5 4.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Patatin PF01734.17 EIW75500.1 - 1.7e-08 34.6 0.0 2.3e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_12 PF13424.1 EIW75501.1 - 1.5e-63 210.6 29.9 8.9e-18 64.0 1.8 4.0 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 EIW75501.1 - 3.3e-55 182.5 12.5 6.9e-12 44.8 0.4 5.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.12 EIW75501.1 - 7e-17 59.9 5.6 0.066 13.1 0.1 5.3 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_17 PF13431.1 EIW75501.1 - 7.3e-15 53.8 1.7 0.41 10.9 0.0 5.4 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_3 PF07720.7 EIW75501.1 - 3.7e-13 48.9 4.8 0.043 13.6 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIW75501.1 - 6.8e-13 48.9 1.2 8.5e-05 23.1 0.3 3.4 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_4 PF07721.9 EIW75501.1 - 9e-13 47.3 3.4 0.73 10.4 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.1 EIW75501.1 - 2.7e-11 42.3 2.8 0.78 9.6 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 EIW75501.1 - 7.8e-11 40.9 12.5 0.11 12.3 0.0 5.2 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 EIW75501.1 - 5.9e-09 35.4 3.9 0.0039 16.8 0.4 3.2 2 1 0 3 3 3 2 TPR repeat Flu_B_M2 PF04772.7 EIW75501.1 - 1.6e-08 34.5 0.1 2.3 8.2 0.0 5.0 1 1 4 5 5 5 1 Influenza B matrix protein 2 (BM2) TPR_1 PF00515.23 EIW75501.1 - 4.5e-08 32.3 6.9 2.6 7.8 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EIW75501.1 - 4.5e-08 33.1 3.0 0.0023 18.0 0.4 4.0 1 1 3 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EIW75501.1 - 7.8e-08 32.5 11.0 0.92 9.8 0.1 4.9 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIW75501.1 - 2e-05 24.7 10.5 5.9 7.8 0.2 5.4 2 1 3 5 5 5 0 Tetratricopeptide repeat DUF2680 PF10925.3 EIW75501.1 - 0.0028 17.4 12.2 4.8 7.1 0.2 4.4 4 0 0 4 4 4 2 Protein of unknown function (DUF2680) GP40 PF11025.3 EIW75501.1 - 0.0065 16.0 0.0 8.1 5.9 0.0 3.7 1 1 3 4 4 4 0 Glycoprotein GP40 of Cryptosporidium Gag_p30 PF02093.11 EIW75501.1 - 0.0067 15.6 9.1 4.8 6.3 0.1 4.1 1 1 3 4 4 4 1 Gag P30 core shell protein PolyA_pol_RNAbd PF12627.2 EIW75501.1 - 0.015 14.8 3.6 9.1 5.9 0.0 5.1 6 0 0 6 6 6 0 Probable RNA and SrmB- binding site of polymerase A DUF832 PF05734.6 EIW75501.1 - 0.026 13.7 1.9 2.2 7.4 0.2 2.3 1 1 0 2 2 2 0 Herpesvirus protein of unknown function (DUF832) Protein_K PF12283.3 EIW75501.1 - 0.028 14.2 5.5 2.9 7.8 0.0 3.6 1 1 3 4 4 4 0 Bacteriophage protein K Dimer_Tnp_Tn5 PF02281.11 EIW75501.1 - 0.033 14.3 1.2 72 3.5 0.0 3.9 4 0 0 4 4 4 0 Transposase Tn5 dimerisation domain mRNA_stabil PF13929.1 EIW75501.1 - 0.12 11.3 2.2 7.4 5.4 0.1 2.9 1 1 2 3 3 3 0 mRNA stabilisation DUF4404 PF14357.1 EIW75501.1 - 0.12 12.8 12.3 2.6 8.5 0.7 3.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4404) TPR_6 PF13174.1 EIW75501.1 - 0.27 11.7 9.3 1.4 9.5 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.1 EIW75501.1 - 0.43 10.7 7.7 2.4 8.3 0.2 3.7 1 1 3 4 4 4 0 Tetratricopeptide repeat NARP1 PF12569.3 EIW75501.1 - 0.82 8.3 9.5 0.72 8.5 0.2 3.4 1 1 3 4 4 4 0 NMDA receptor-regulated protein 1 Mei4 PF13971.1 EIW75501.1 - 1.4 7.7 14.8 1.1 8.0 0.3 3.8 1 1 3 4 4 4 0 Meiosis-specific protein Mei4 DUF4157 PF13699.1 EIW75501.1 - 2.1 8.5 6.4 15 5.8 0.1 3.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4157) CCDC92 PF14916.1 EIW75501.1 - 7.6 6.2 18.7 11 5.7 0.2 5.1 3 1 0 5 5 5 0 Coiled-coil domain of unknown function Solute_trans_a PF03619.11 EIW75502.1 - 5.8e-99 330.8 7.7 7.6e-99 330.4 5.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Fungal_trans PF04082.13 EIW75503.1 - 3.3e-24 85.1 0.0 5.4e-24 84.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW75503.1 - 1.2e-09 37.9 11.6 2.3e-09 36.9 8.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EIIBC-GUT_C PF07663.6 EIW75504.1 - 0.14 12.2 0.4 2.5 8.2 0.1 2.7 3 0 0 3 3 3 0 Sorbitol phosphotransferase enzyme II C-terminus DUF92 PF01940.11 EIW75505.1 - 2.9e-05 23.3 0.0 5.5e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Integral membrane protein DUF92 Nuc_N PF14448.1 EIW75509.1 - 0.13 11.8 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Nuclease N terminal SPC25 PF06703.6 EIW75510.1 - 0.058 12.9 0.4 0.1 12.1 0.3 1.4 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) adh_short PF00106.20 EIW75512.1 - 1.5e-07 31.4 0.1 3e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EIW75512.1 - 3.8e-05 23.7 0.3 0.00014 21.9 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding DUF3846 PF12957.2 EIW75512.1 - 0.091 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) DUF4218 PF13960.1 EIW75513.1 - 0.027 13.9 0.1 0.053 12.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Nop14 PF04147.7 EIW75516.1 - 0.28 9.0 29.3 0.44 8.4 20.3 1.3 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.6 EIW75516.1 - 0.66 8.0 6.1 1 7.4 4.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nucleoplasmin PF03066.10 EIW75516.1 - 7.9 5.9 23.1 21 4.6 16.0 1.8 1 0 0 1 1 1 0 Nucleoplasmin Cyc-maltodext_C PF10438.4 EIW75517.1 - 0.037 14.0 0.0 0.094 12.7 0.0 1.6 1 0 0 1 1 1 0 Cyclo-malto-dextrinase C-terminal domain zf-B_box PF00643.19 EIW75517.1 - 1 9.3 9.5 0.23 11.3 3.7 2.2 2 0 0 2 2 2 0 B-box zinc finger Tet_JBP PF12851.2 EIW75518.1 - 1.3e-15 57.1 0.0 1.6e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Striatin PF08232.7 EIW75520.1 - 0.00083 19.6 0.0 0.00083 19.6 0.0 2.7 3 1 0 3 3 3 1 Striatin family TIM PF00121.13 EIW75523.1 - 1.3e-84 283.0 0.0 1.5e-84 282.8 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase adh_short PF00106.20 EIW75524.1 - 9.3e-32 110.2 2.7 1.4e-31 109.6 1.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW75524.1 - 3.7e-28 98.9 0.4 4.4e-28 98.6 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW75524.1 - 1e-13 51.3 1.7 1.5e-13 50.7 1.2 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW75524.1 - 0.0025 17.2 0.1 0.34 10.3 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family CoA_binding_2 PF13380.1 EIW75524.1 - 0.06 13.5 0.4 0.48 10.6 0.1 2.1 2 0 0 2 2 2 0 CoA binding domain PCP_red PF08369.5 EIW75524.1 - 0.093 12.6 0.1 2.1 8.2 0.0 2.7 3 0 0 3 3 3 0 Proto-chlorophyllide reductase 57 kD subunit Hemerythrin PF01814.18 EIW75525.1 - 7.6e-16 58.4 2.7 1.2e-15 57.8 1.8 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Hemerythrin PF01814.18 EIW75526.1 - 8.9e-15 55.0 2.8 1.2e-14 54.5 2.0 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain AA_permease_2 PF13520.1 EIW75529.1 - 1.2e-61 208.5 49.3 1.5e-61 208.2 34.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIW75529.1 - 1.1e-14 53.7 46.2 1.5e-14 53.2 32.0 1.1 1 0 0 1 1 1 1 Amino acid permease WD40 PF00400.27 EIW75530.1 - 6e-13 48.1 0.0 0.0002 21.1 0.0 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat F-box-like PF12937.2 EIW75530.1 - 1.4e-07 31.1 9.5 1.7e-07 30.8 3.2 2.5 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 EIW75530.1 - 1.3e-06 27.8 3.4 1.7e-06 27.5 0.4 2.2 2 0 0 2 2 2 1 F-box domain PQQ_2 PF13360.1 EIW75530.1 - 0.00031 20.2 0.0 0.24 10.8 0.0 2.8 2 1 1 3 3 3 2 PQQ-like domain adh_short PF00106.20 EIW75531.1 - 9.5e-35 119.9 0.7 1.1e-34 119.7 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW75531.1 - 6.9e-17 61.6 0.4 9e-17 61.3 0.3 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIW75531.1 - 3e-16 59.9 0.0 3.7e-16 59.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EIW75531.1 - 0.0013 18.2 0.2 0.03 13.7 0.1 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIW75531.1 - 0.059 12.0 0.2 0.084 11.5 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EIW75532.1 - 1e-64 217.4 5.9 2.3e-32 112.2 0.2 2.6 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.1 EIW75532.1 - 2e-46 158.7 0.0 4.6e-22 78.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW75532.1 - 7.1e-31 107.2 3.4 9.3e-15 54.7 0.2 2.4 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 EIW75532.1 - 7.5e-07 28.8 1.3 0.079 12.3 0.0 3.6 2 2 0 2 2 2 2 NAD dependent epimerase/dehydratase family HHH_5 PF14520.1 EIW75532.1 - 0.00012 22.1 0.8 1.8 8.7 0.0 3.7 3 0 0 3 3 3 2 Helix-hairpin-helix domain NAD_binding_10 PF13460.1 EIW75532.1 - 0.00015 21.8 4.2 0.017 15.0 0.2 2.9 2 2 0 2 2 2 2 NADH(P)-binding Cu-oxidase_3 PF07732.10 EIW75532.1 - 0.022 14.5 0.1 0.27 10.9 0.0 2.3 2 0 0 2 2 2 0 Multicopper oxidase Eno-Rase_NADH_b PF12242.3 EIW75532.1 - 0.031 14.0 2.0 4.1 7.2 0.1 2.6 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 3HCDH_N PF02737.13 EIW75532.1 - 0.074 12.6 0.2 5.2 6.6 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SNARE PF05739.14 EIW75533.1 - 7.7e-07 28.7 0.1 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 SNARE domain Clc-like PF07062.7 EIW75535.1 - 0.16 11.1 2.9 0.26 10.4 2.0 1.3 1 0 0 1 1 1 0 Clc-like Methyltransf_25 PF13649.1 EIW75536.1 - 1.7e-05 25.1 0.0 3.1e-05 24.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW75536.1 - 0.039 14.5 0.0 0.052 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EIW75536.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain zf-C2H2_4 PF13894.1 EIW75537.1 - 0.009 16.2 0.2 0.016 15.5 0.2 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger TPR_MLP1_2 PF07926.7 EIW75537.1 - 0.06 13.0 8.6 0.085 12.5 5.4 1.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein EIIBC-GUT_N PF03612.9 EIW75537.1 - 0.061 12.9 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus zf-C2H2 PF00096.21 EIW75537.1 - 0.062 13.6 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type YccJ PF13993.1 EIW75537.1 - 0.072 13.1 0.5 0.49 10.5 0.0 2.4 2 0 0 2 2 2 0 YccJ-like protein APG6 PF04111.7 EIW75537.1 - 0.09 11.8 5.9 0.15 11.0 4.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 EIW75537.1 - 0.11 12.9 2.2 0.23 11.8 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF972) YbjQ_1 PF01906.12 EIW75537.1 - 0.17 12.3 0.9 0.31 11.4 0.3 1.7 1 1 0 1 1 1 0 Putative heavy-metal-binding V_ATPase_I PF01496.14 EIW75537.1 - 0.3 8.8 4.7 0.36 8.6 3.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.6 EIW75537.1 - 1 9.1 11.2 1.5 8.6 1.0 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) YlqD PF11068.3 EIW75537.1 - 2.1 8.3 10.6 0.92 9.5 4.2 2.2 1 1 0 2 2 2 0 YlqD protein Atg14 PF10186.4 EIW75537.1 - 6.7 5.5 7.4 10 4.9 5.1 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 EIW75537.1 - 7.6 6.1 10.9 75 2.9 7.5 2.3 1 1 0 1 1 1 0 Mnd1 family Beach PF02138.13 EIW75538.1 - 1.3e-99 333.0 0.0 1.8e-99 332.5 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain Laminin_G_3 PF13385.1 EIW75538.1 - 3.9e-10 40.1 1.2 6.6e-10 39.4 0.0 2.0 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily PH_BEACH PF14844.1 EIW75538.1 - 1.8e-09 37.4 0.0 3.6e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EIW75538.1 - 0.00011 21.8 1.1 0.33 10.8 0.1 3.1 2 0 0 2 2 2 2 WD domain, G-beta repeat AA_permease_2 PF13520.1 EIW75539.1 - 6e-42 143.6 42.6 6e-29 100.8 14.3 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 EIW75539.1 - 5e-06 25.1 41.0 2e-05 23.1 7.8 3.2 2 1 1 3 3 3 2 Amino acid permease Herpes_US9 PF06072.6 EIW75539.1 - 2.2 8.2 0.0 2.2 8.2 0.0 3.2 4 0 0 4 4 4 0 Alphaherpesvirus tegument protein US9 AA_permease_2 PF13520.1 EIW75540.1 - 1.4e-55 188.6 51.6 1.9e-55 188.1 35.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIW75540.1 - 1.9e-13 49.5 46.9 2.5e-13 49.1 32.5 1.1 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.20 EIW75541.1 - 1.7e-15 57.3 1.4 4.3e-12 46.2 0.1 3.5 3 1 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.1 EIW75541.1 - 1.1e-07 31.8 0.0 0.00048 19.9 0.0 2.6 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW75541.1 - 6e-06 26.0 0.4 1.2e-05 25.0 0.3 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW75541.1 - 0.0044 16.4 0.3 0.41 10.0 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Cu-oxidase_3 PF07732.10 EIW75541.1 - 0.0084 15.8 0.1 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 Multicopper oxidase HHH_5 PF14520.1 EIW75541.1 - 0.11 12.6 0.0 9.1 6.5 0.0 2.8 2 1 0 2 2 2 0 Helix-hairpin-helix domain adh_short PF00106.20 EIW75542.1 - 8.5e-34 116.8 1.1 1.1e-33 116.4 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW75542.1 - 3.1e-27 95.8 0.1 3.7e-27 95.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW75542.1 - 1.7e-13 50.6 0.8 2.9e-13 49.8 0.5 1.4 1 0 0 1 1 1 1 KR domain dCMP_cyt_deam_1 PF00383.17 EIW75543.1 - 1.3e-10 40.7 0.0 2.1e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EIW75543.1 - 0.0021 17.9 0.4 0.14 12.0 0.3 2.3 1 1 0 1 1 1 1 Bd3614-like deaminase Profilin PF00235.14 EIW75545.1 - 8.4e-35 119.5 0.2 9.5e-35 119.3 0.2 1.0 1 0 0 1 1 1 1 Profilin DNA_pol_A_exo1 PF01612.15 EIW75546.1 - 7.7e-10 38.5 0.0 1.4e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 3'-5' exonuclease CAV_VP3 PF04771.7 EIW75546.1 - 0.021 14.7 0.0 0.034 14.1 0.0 1.3 1 0 0 1 1 1 0 Chicken anaemia virus VP-3 protein Sec61_beta PF03911.11 EIW75547.1 - 7.2e-19 67.3 0.5 9.2e-19 66.9 0.3 1.1 1 0 0 1 1 1 1 Sec61beta family Synaptobrevin PF00957.16 EIW75548.1 - 4.3e-31 106.3 0.3 6.3e-31 105.8 0.2 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EIW75548.1 - 7.3e-21 73.5 0.0 1.1e-20 72.9 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain ClpB_D2-small PF10431.4 EIW75548.1 - 0.11 12.3 0.3 0.29 11.0 0.2 1.7 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein zf-RING_5 PF14634.1 EIW75551.1 - 1.1e-08 34.6 6.8 1.6e-08 34.0 4.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EIW75551.1 - 3.4e-07 29.9 8.7 5.4e-07 29.3 6.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIW75551.1 - 5.2e-06 26.0 5.0 7.8e-06 25.4 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW75551.1 - 6.2e-05 22.9 9.4 9.9e-05 22.2 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIW75551.1 - 0.00094 19.0 9.5 0.0019 18.0 6.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EIW75551.1 - 0.00095 18.8 3.1 0.0036 17.0 2.1 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EIW75551.1 - 0.00095 18.7 8.8 0.0015 18.0 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EIW75551.1 - 0.012 15.1 5.6 0.029 13.9 3.9 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EIW75551.1 - 0.016 14.7 4.1 0.027 14.0 2.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 EIW75551.1 - 0.09 12.5 2.8 0.18 11.6 1.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FYVE PF01363.16 EIW75551.1 - 0.38 10.6 4.2 2.5 8.0 2.8 2.1 1 1 0 1 1 1 0 FYVE zinc finger DUF605 PF04652.11 EIW75551.1 - 0.98 8.7 42.0 2.1 7.6 12.5 2.3 2 0 0 2 2 2 0 Vta1 like Acyltransferase PF01553.16 EIW75552.1 - 1.1e-14 53.9 0.0 1.9e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Ribosomal_S11 PF00411.14 EIW75553.1 - 4.5e-41 139.4 0.5 5.6e-41 139.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 HTH_31 PF13560.1 EIW75554.1 - 1.4e-05 25.1 0.0 1.7e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.2 EIW75554.1 - 3.9e-05 23.6 0.0 5e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.17 EIW75554.1 - 0.0085 15.9 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix zf-RING_2 PF13639.1 EIW75555.1 - 2.1e-07 30.6 13.2 4.7e-07 29.5 9.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIW75555.1 - 4.5e-07 29.4 9.9 9.5e-07 28.3 6.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW75555.1 - 3.1e-06 26.7 12.2 6.5e-06 25.7 8.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIW75555.1 - 5.5e-06 26.3 14.0 1.2e-05 25.1 9.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW75555.1 - 5.5e-05 22.7 13.6 0.00011 21.7 9.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIW75555.1 - 0.00033 20.3 5.9 0.00033 20.3 4.1 2.4 2 0 0 2 2 2 1 RING-type zinc-finger MMS19_C PF12460.3 EIW75555.1 - 0.0025 16.6 0.4 0.0031 16.2 0.2 1.1 1 0 0 1 1 1 1 RNAPII transcription regulator C-terminal zf-C3HC4_4 PF15227.1 EIW75555.1 - 0.0096 15.7 12.5 0.0096 15.7 8.7 2.1 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EIW75555.1 - 0.026 14.1 9.4 0.026 14.1 6.5 1.9 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Nairovirus_M PF07948.6 EIW75555.1 - 0.083 10.9 1.7 0.12 10.4 1.2 1.2 1 0 0 1 1 1 0 Nairovirus M polyprotein-like FYVE PF01363.16 EIW75555.1 - 0.15 12.0 16.9 0.14 12.0 7.2 3.1 2 2 1 3 3 3 0 FYVE zinc finger zf-rbx1 PF12678.2 EIW75555.1 - 0.87 9.7 6.8 2.9 8.0 4.7 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger Baculo_IE-1 PF05290.6 EIW75555.1 - 0.96 9.1 6.7 2.2 7.9 3.1 2.2 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Rtf2 PF04641.7 EIW75555.1 - 1.2 8.2 7.8 0.16 11.1 0.7 2.4 2 1 1 3 3 3 0 Rtf2 RING-finger Pellino PF04710.9 EIW75555.1 - 2.8 6.5 4.9 0.65 8.5 1.0 1.6 2 0 0 2 2 2 0 Pellino zf-RING_6 PF14835.1 EIW75555.1 - 3 7.6 6.3 7.7 6.3 4.3 1.8 1 1 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 EIW75555.1 - 3.5 7.2 11.6 2.1 7.9 0.2 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF3039 PF11238.3 EIW75555.1 - 7.2 6.1 11.1 18 4.8 4.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3039) GLE1 PF07817.8 EIW75556.1 - 6.2e-35 120.3 0.0 6.2e-35 120.3 0.0 2.8 1 1 1 3 3 3 1 GLE1-like protein Macoilin PF09726.4 EIW75556.1 - 2 6.6 37.9 3 6.0 26.3 1.2 1 0 0 1 1 1 0 Transmembrane protein E1-E2_ATPase PF00122.15 EIW75558.1 - 3.3e-49 166.9 1.6 3.3e-49 166.9 1.1 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EIW75558.1 - 1.7e-31 109.1 5.0 1.7e-31 109.1 3.4 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EIW75558.1 - 1.1e-29 104.4 0.0 2.2e-29 103.4 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIW75558.1 - 2.2e-20 72.3 0.0 4.1e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EIW75558.1 - 3.3e-14 53.5 0.0 1.3e-13 51.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIW75558.1 - 2.3e-07 30.6 0.7 2.3e-07 30.6 0.5 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Phage_GP20 PF06810.6 EIW75559.1 - 0.72 9.2 9.1 0.44 9.9 5.1 1.5 2 0 0 2 2 2 0 Phage minor structural protein GP20 Herpes_UL25 PF01499.11 EIW75560.1 - 0.031 12.5 2.3 0.047 12.0 1.6 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family DivIC PF04977.10 EIW75560.1 - 0.053 13.0 2.3 0.45 10.0 0.7 2.3 2 0 0 2 2 2 0 Septum formation initiator DUF4242 PF14026.1 EIW75560.1 - 0.2 11.7 0.8 0.4 10.8 0.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4242) HOASN PF14515.1 EIW75563.1 - 0.057 13.7 1.0 0.89 9.9 0.1 2.5 2 0 0 2 2 2 0 Haem-oxygenase-associated N-terminal helices DUF605 PF04652.11 EIW75563.1 - 0.068 12.5 23.8 0.1 11.9 16.5 1.3 1 0 0 1 1 1 0 Vta1 like Suf PF05843.9 EIW75563.1 - 0.55 9.9 9.4 0.89 9.2 6.5 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.11 EIW75563.1 - 1.1 9.0 4.3 1.8 8.3 3.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rtf2 PF04641.7 EIW75563.1 - 2.1 7.5 11.9 3.3 6.8 8.3 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Hid1 PF12722.2 EIW75563.1 - 2.5 5.6 5.1 3.1 5.3 3.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pol_alpha_B_N PF08418.5 EIW75563.1 - 4.5 6.7 16.8 10 5.5 11.6 1.6 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DDHD PF02862.12 EIW75563.1 - 6.7 6.4 9.9 34 4.1 7.5 1.6 2 0 0 2 2 2 0 DDHD domain DPM3 PF08285.6 EIW75564.1 - 8.3e-33 112.1 0.1 9.2e-33 111.9 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF3937 PF13073.1 EIW75564.1 - 0.064 13.1 0.8 0.09 12.6 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3937) FixP_N PF14715.1 EIW75564.1 - 4.2 6.8 9.0 0.78 9.1 0.8 2.2 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP IncA PF04156.9 EIW75567.1 - 0.99 8.9 6.9 2.6 7.6 4.8 1.7 1 1 0 1 1 1 0 IncA protein ADIP PF11559.3 EIW75567.1 - 3.8 7.3 7.8 1.3 8.9 1.8 2.1 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Transposase_21 PF02992.9 EIW75569.1 - 0.00012 21.2 0.0 0.00027 20.1 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 zf-C2HC5 PF06221.8 EIW75569.1 - 0.018 14.8 0.2 0.042 13.5 0.2 1.6 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type DUF4218 PF13960.1 EIW75570.1 - 5.8e-06 25.7 0.0 9.1e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Sec5 PF15469.1 EIW75573.1 - 0.07 12.8 0.0 0.15 11.7 0.0 1.5 2 0 0 2 2 2 0 Exocyst complex component Sec5 DUF1019 PF06254.6 EIW75574.1 - 0.32 11.1 2.9 0.47 10.6 1.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1019) Calici_coat PF00915.15 EIW75575.1 - 0.022 13.6 0.1 0.03 13.2 0.1 1.2 1 0 0 1 1 1 0 Calicivirus coat protein Calpain_inhib PF00748.14 EIW75575.1 - 0.15 12.3 3.8 0.097 13.0 1.4 1.6 2 0 0 2 2 2 0 Calpain inhibitor DUF1777 PF08648.7 EIW75577.1 - 1.4 8.5 12.2 1.5 8.5 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) DUF1509 PF07420.6 EIW75577.1 - 6.2 5.9 10.8 6.8 5.8 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Pantoate_transf PF02548.10 EIW75578.1 - 1.7e-100 335.5 0.0 1.9e-100 335.2 0.0 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EIW75578.1 - 1.1e-09 37.8 0.2 2.4e-09 36.7 0.0 1.5 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Aldolase_II PF00596.16 EIW75580.1 - 3.1e-44 150.7 0.4 3.8e-44 150.4 0.3 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain F-box-like PF12937.2 EIW75581.1 - 8.1e-10 38.2 3.3 2e-09 37.0 2.3 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EIW75581.1 - 0.0011 18.6 1.1 0.035 13.8 0.2 2.9 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.2 EIW75581.1 - 0.14 11.8 2.1 1.9 8.1 0.2 3.3 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Pkinase PF00069.20 EIW75582.1 - 9.1e-36 123.3 0.0 2.4e-35 121.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW75582.1 - 1.9e-10 40.2 0.0 9.9e-08 31.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EIW75582.1 - 0.0023 17.6 1.2 0.038 13.7 0.1 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EIW75582.1 - 0.072 12.1 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pyr_redox_dim PF02852.17 EIW75583.1 - 1.1e-41 141.2 0.2 1.1e-41 141.2 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EIW75583.1 - 1.4e-37 129.5 19.3 2.8e-35 122.0 13.4 3.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW75583.1 - 4.6e-22 78.2 9.1 3.1e-19 69.1 2.1 3.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW75583.1 - 3.6e-11 43.4 0.4 6.3e-07 29.6 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIW75583.1 - 1.5e-10 40.4 0.8 1.5e-10 40.4 0.6 2.3 2 1 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EIW75583.1 - 8.4e-10 38.2 0.2 8.4e-10 38.2 0.1 3.0 2 1 1 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW75583.1 - 3.2e-09 36.6 4.0 5.8e-05 23.0 0.1 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIW75583.1 - 3.3e-08 32.8 16.2 0.0066 15.3 0.2 4.3 3 1 1 4 4 4 4 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW75583.1 - 7.8e-07 28.2 2.5 7.8e-07 28.2 1.7 3.5 3 1 1 4 4 4 1 FAD binding domain K_oxygenase PF13434.1 EIW75583.1 - 1.8e-06 27.1 0.5 0.035 13.0 0.1 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EIW75583.1 - 2.1e-06 26.4 15.3 0.0003 19.3 0.8 4.0 4 0 0 4 4 4 2 HI0933-like protein Thi4 PF01946.12 EIW75583.1 - 7.5e-05 21.9 5.3 0.00032 19.8 0.0 2.5 2 0 0 2 2 2 1 Thi4 family AlaDh_PNT_C PF01262.16 EIW75583.1 - 0.001 18.6 4.9 0.16 11.5 0.2 2.9 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 EIW75583.1 - 0.0015 17.6 9.5 0.062 12.3 0.3 3.8 3 1 1 4 4 4 1 FAD binding domain Amino_oxidase PF01593.19 EIW75583.1 - 0.0082 15.2 0.5 0.032 13.3 0.1 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase THF_DHG_CYH_C PF02882.14 EIW75583.1 - 0.011 14.7 0.4 0.011 14.7 0.2 2.4 3 1 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_9 PF13454.1 EIW75583.1 - 0.055 13.2 4.7 13 5.4 0.1 3.5 3 0 0 3 3 3 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EIW75583.1 - 1.2 7.9 7.1 0.58 9.0 0.3 3.1 3 1 0 3 3 3 0 Lycopene cyclase protein Aldolase_II PF00596.16 EIW75584.1 - 7.2e-45 152.8 0.2 9e-45 152.5 0.2 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain F-box-like PF12937.2 EIW75585.1 - 3.4e-10 39.4 2.8 3.4e-10 39.4 1.9 2.1 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 EIW75585.1 - 0.0054 16.4 3.4 0.033 13.9 0.2 3.1 2 1 0 2 2 2 1 Leucine rich repeat LRR_7 PF13504.1 EIW75585.1 - 0.25 11.7 1.2 97 3.8 0.0 4.5 3 1 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 EIW75585.1 - 0.36 10.5 4.4 8.9 6.0 0.6 4.0 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) Toxin_YhaV PF11663.3 EIW75587.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Toxin with endonuclease activity YhaV adh_short PF00106.20 EIW75588.1 - 4.4e-17 62.4 0.5 6.3e-17 61.9 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIW75588.1 - 2.7e-09 36.9 0.4 4e-09 36.3 0.3 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIW75588.1 - 5.9e-09 36.0 0.0 8.2e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIW75588.1 - 5e-05 23.3 1.4 0.00037 20.5 0.4 2.6 3 1 0 3 3 3 1 NADH(P)-binding Epimerase PF01370.16 EIW75588.1 - 0.00066 19.1 0.0 0.00083 18.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family YjeF_N PF03853.10 EIW75588.1 - 0.011 15.3 0.8 0.026 14.1 0.6 1.6 1 1 0 1 1 1 0 YjeF-related protein N-terminus Shikimate_DH PF01488.15 EIW75588.1 - 0.012 15.7 0.7 0.051 13.6 0.2 2.2 2 1 1 3 3 3 0 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EIW75588.1 - 0.034 13.1 0.1 3.1 6.6 0.1 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 EIW75588.1 - 0.053 13.1 0.3 0.086 12.4 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Suc_Fer-like PF06999.7 EIW75590.1 - 1.3e-28 100.6 0.0 3.9e-28 99.0 0.0 1.7 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Lactonase PF10282.4 EIW75591.1 - 5.6e-35 121.0 0.1 6.9e-35 120.7 0.1 1.1 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller HTH_IclR PF09339.5 EIW75592.1 - 0.026 14.0 0.2 0.47 10.0 0.0 2.7 3 0 0 3 3 3 0 IclR helix-turn-helix domain NACHT PF05729.7 EIW75592.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Acetyltransf_1 PF00583.19 EIW75593.1 - 2.8e-12 46.4 0.0 4.3e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIW75593.1 - 8.9e-11 41.8 0.0 1.3e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIW75593.1 - 0.0045 17.1 0.0 0.0075 16.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIW75593.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIW75593.1 - 0.078 13.0 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW75594.1 - 0.00019 21.3 0.0 0.00034 20.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIW75594.1 - 0.0084 16.2 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain p450 PF00067.17 EIW75595.1 - 1.9e-65 221.2 0.0 3.9e-65 220.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 TPR_12 PF13424.1 EIW75596.1 - 1.3e-55 185.2 21.1 6.7e-17 61.1 1.4 3.3 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 EIW75596.1 - 3.2e-55 182.5 16.2 4.5e-13 48.6 0.1 5.1 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.12 EIW75596.1 - 3.5e-15 54.6 7.6 0.063 13.2 0.2 5.3 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 EIW75596.1 - 2.2e-14 53.6 2.4 0.00012 22.6 0.0 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EIW75596.1 - 4.1e-12 45.5 4.1 0.00013 21.5 0.3 3.3 1 1 0 3 3 3 3 TPR repeat TPR_17 PF13431.1 EIW75596.1 - 1e-11 44.0 1.5 0.79 10.0 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIW75596.1 - 1.8e-10 39.7 7.8 0.079 12.8 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.9 EIW75596.1 - 2e-10 40.0 7.6 0.034 14.5 0.4 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIW75596.1 - 4.7e-10 38.6 3.2 0.32 10.6 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_3 PF07720.7 EIW75596.1 - 1.6e-09 37.3 0.5 0.15 11.9 0.0 5.2 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIW75596.1 - 1.3e-08 33.9 0.7 0.37 10.6 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIW75596.1 - 6.3e-06 26.4 11.1 0.19 12.0 0.6 5.1 2 2 2 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EIW75596.1 - 3e-05 24.0 2.3 3.6 7.7 0.1 3.7 1 1 3 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EIW75596.1 - 6.9e-05 23.1 11.5 7.1 7.5 0.1 5.6 1 1 4 5 5 5 0 Tetratricopeptide repeat PPR PF01535.15 EIW75596.1 - 0.00012 21.8 0.1 2.9 8.0 0.0 5.4 6 0 0 6 6 6 1 PPR repeat DUF3366 PF11846.3 EIW75596.1 - 0.00081 19.3 1.4 0.92 9.3 0.1 2.6 1 1 1 2 2 2 2 Domain of unknown function (DUF3366) TPR_6 PF13174.1 EIW75596.1 - 0.0019 18.5 7.7 11 6.7 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat PPR_1 PF12854.2 EIW75596.1 - 0.003 16.9 1.4 0.62 9.5 0.0 3.9 4 0 0 4 4 4 1 PPR repeat DPM3 PF08285.6 EIW75596.1 - 0.0084 15.9 2.2 22 4.9 0.0 3.3 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Gag_p30 PF02093.11 EIW75596.1 - 0.011 15.0 5.1 3.4 6.7 0.1 3.3 1 1 1 3 3 3 0 Gag P30 core shell protein DUF2680 PF10925.3 EIW75596.1 - 0.037 13.8 5.6 17 5.3 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2680) NARP1 PF12569.3 EIW75596.1 - 0.086 11.5 2.8 0.16 10.6 0.6 2.1 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF2989 PF11207.3 EIW75596.1 - 0.1 12.0 0.1 1 8.7 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2989) TPR_5 PF12688.2 EIW75596.1 - 0.25 11.3 7.5 3.6 7.6 0.3 3.1 1 1 2 3 3 3 0 Tetratrico peptide repeat TPR_9 PF13371.1 EIW75596.1 - 0.27 11.0 7.4 7.5 6.4 0.0 4.3 2 2 2 4 4 4 0 Tetratricopeptide repeat Abhydrolase_3 PF07859.8 EIW75597.1 - 1.2e-36 126.2 0.0 1.7e-36 125.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 EIW75597.1 - 0.001 18.0 0.0 0.0014 17.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.2 EIW75597.1 - 0.0018 18.0 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIW75597.1 - 0.0081 15.4 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 EIW75597.1 - 0.021 14.1 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF2974 PF11187.3 EIW75597.1 - 0.054 12.8 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) UBN2_2 PF14227.1 EIW75600.1 - 1.3e-06 27.9 0.0 2.6e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIW75600.1 - 6.2e-05 22.7 0.0 9.8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type ADPrib_exo_Tox PF03496.9 EIW75600.1 - 0.051 12.7 0.7 0.089 12.0 0.1 1.6 2 0 0 2 2 2 0 ADP-ribosyltransferase exoenzyme PBP1_TM PF14812.1 EIW75600.1 - 0.62 10.4 9.3 0.68 10.2 1.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SPT6_acidic PF14632.1 EIW75600.1 - 1.4 9.1 12.4 2.2 8.4 3.1 2.5 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Bd3614-deam PF14439.1 EIW75601.1 - 0.46 10.3 2.9 0.45 10.3 0.2 1.9 2 0 0 2 2 2 0 Bd3614-like deaminase Mo25 PF08569.6 EIW75607.1 - 8.4e-123 409.6 4.4 9.4e-123 409.5 3.0 1.0 1 0 0 1 1 1 1 Mo25-like DUF3554 PF12074.3 EIW75607.1 - 0.079 12.3 0.0 0.86 8.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3554) Lipocalin_7 PF14651.1 EIW75607.1 - 0.081 12.6 0.1 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipocalin / cytosolic fatty-acid binding protein family RepA_N PF06970.6 EIW75607.1 - 0.25 11.1 2.8 0.22 11.3 0.4 2.2 2 0 0 2 2 2 0 Replication initiator protein A (RepA) N-terminus Nucleoside_tran PF01733.13 EIW75608.1 - 2.5e-22 79.4 15.3 4.6e-13 49.0 2.3 3.8 1 1 2 3 3 3 3 Nucleoside transporter FA_desaturase PF00487.19 EIW75608.1 - 0.64 9.4 6.2 0.22 10.9 1.5 2.1 1 1 1 2 2 2 0 Fatty acid desaturase ESX-1_EspG PF14011.1 EIW75609.1 - 0.083 12.1 0.3 8.9 5.4 0.1 2.2 2 0 0 2 2 2 0 EspG family F-box-like PF12937.2 EIW75610.1 - 0.027 14.2 0.0 0.062 13.0 0.0 1.6 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 EIW75610.1 - 0.086 12.5 0.4 0.18 11.4 0.2 1.5 1 0 0 1 1 1 0 F-box domain CBM_5_12 PF02839.9 EIW75611.1 - 2.6e-10 39.7 15.0 2.6e-10 39.7 10.4 2.0 2 0 0 2 2 2 1 Carbohydrate binding domain Ribosomal_L24e PF01246.15 EIW75612.1 - 4.6e-31 106.4 0.3 4.6e-31 106.4 0.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e MAD PF05557.8 EIW75612.1 - 0.0075 14.4 2.4 0.0081 14.3 1.7 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein TerB-C PF15615.1 EIW75612.1 - 0.47 10.6 2.9 0.67 10.2 2.0 1.1 1 0 0 1 1 1 0 TerB-C domain COX16 PF14138.1 EIW75612.1 - 2 8.6 4.2 1.7 8.8 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 WD40 PF00400.27 EIW75614.1 - 2.2e-46 154.1 17.6 1.1e-10 40.9 0.1 6.1 6 0 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 EIW75614.1 - 6.3e-05 22.7 0.0 0.013 15.1 0.0 2.2 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EIW75614.1 - 0.00049 19.7 1.1 0.84 9.3 0.0 4.3 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.1 EIW75614.1 - 0.00055 19.6 0.0 0.052 13.3 0.0 2.4 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Nbas_N PF15492.1 EIW75614.1 - 0.0017 17.5 0.2 1.1 8.2 0.0 2.9 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 EIW75614.1 - 0.0022 16.8 2.7 1.3 7.6 0.2 3.5 1 1 2 3 3 3 2 Nup133 N terminal like DUF3312 PF11768.3 EIW75614.1 - 0.0098 14.1 0.0 0.04 12.1 0.0 1.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3312) Cytochrom_D1 PF02239.11 EIW75614.1 - 0.024 12.9 0.2 0.091 11.0 0.1 1.8 1 1 0 1 1 1 0 Cytochrome D1 heme domain Gmad1 PF10647.4 EIW75614.1 - 0.17 11.2 1.9 3.3 7.0 0.4 2.6 2 1 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain WD40 PF00400.27 EIW75615.1 - 3.2e-65 213.8 21.1 2.8e-12 46.0 0.0 7.6 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EIW75615.1 - 7.7e-10 37.5 1.5 0.19 9.8 0.0 4.7 1 1 3 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.6 EIW75615.1 - 0.0001 22.0 0.0 0.0076 15.9 0.0 2.7 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EIW75615.1 - 0.0067 15.2 0.7 3.1 6.4 0.0 3.2 1 1 0 3 3 3 2 Nup133 N terminal like Gmad1 PF10647.4 EIW75615.1 - 0.032 13.6 0.0 11 5.3 0.0 3.7 2 2 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain IKI3 PF04762.7 EIW75615.1 - 0.18 9.5 0.0 10 3.8 0.0 2.5 2 2 1 3 3 3 0 IKI3 family Ferritin_2 PF13668.1 EIW75616.1 - 3.1e-40 137.2 4.3 4.4e-40 136.8 3.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain Pkinase PF00069.20 EIW75617.1 - 0.046 12.8 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein kinase domain HD PF01966.17 EIW75618.1 - 4.6e-07 29.8 0.0 8.6e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 HD domain Synaptobrevin PF00957.16 EIW75619.1 - 1.1e-33 114.7 3.5 1.2e-33 114.5 2.5 1.0 1 0 0 1 1 1 1 Synaptobrevin TMEM117 PF15113.1 EIW75619.1 - 0.015 13.9 1.0 0.019 13.5 0.7 1.0 1 0 0 1 1 1 0 TMEM117 protein family DUF515 PF04415.7 EIW75619.1 - 0.059 11.6 0.3 0.063 11.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Pkinase PF00069.20 EIW75620.1 - 4.4e-73 245.6 0.0 7.5e-73 244.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW75620.1 - 3.4e-40 137.7 0.0 4.8e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW75620.1 - 2.1e-11 43.3 0.0 3.2e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIW75620.1 - 0.0059 15.6 0.1 0.012 14.6 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short PF00106.20 EIW75621.1 - 1.8e-07 31.2 0.1 2.9e-07 30.5 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW75621.1 - 0.0025 17.5 0.0 0.012 15.2 0.0 1.9 2 0 0 2 2 2 1 KR domain WD40 PF00400.27 EIW75622.1 - 1.1e-81 266.0 45.9 1.1e-11 44.1 0.0 11.4 11 1 0 11 11 11 11 WD domain, G-beta repeat BBS2_Mid PF14783.1 EIW75622.1 - 6.4e-07 29.1 0.0 0.43 10.3 0.0 4.6 4 1 1 5 5 5 3 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 EIW75622.1 - 6.5e-07 29.2 0.0 0.00083 19.1 0.0 4.3 2 2 3 5 5 5 3 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 EIW75622.1 - 4e-05 23.1 1.5 0.47 9.7 0.2 3.9 3 2 0 3 3 3 2 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 EIW75622.1 - 0.00021 20.8 1.7 12 5.7 0.0 6.4 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EIW75622.1 - 0.00034 18.8 5.0 0.4 8.7 0.1 4.4 3 1 2 5 5 5 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EIW75622.1 - 0.006 16.0 1.7 0.33 10.3 0.3 3.5 2 2 1 3 3 3 1 PQQ-like domain DUF3312 PF11768.3 EIW75622.1 - 0.08 11.1 0.1 8 4.5 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3312) IKI3 PF04762.7 EIW75622.1 - 0.086 10.6 0.0 4.8 4.8 0.0 2.7 3 1 0 3 3 3 0 IKI3 family CENP-B_dimeris PF09026.5 EIW75627.1 - 0.044 14.0 1.5 0.08 13.1 1.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF2457 PF10446.4 EIW75627.1 - 0.42 9.2 2.8 0.55 8.8 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) HD PF01966.17 EIW75630.1 - 0.01 15.8 0.0 0.02 14.8 0.0 1.7 1 1 0 1 1 1 0 HD domain Aminotran_5 PF00266.14 EIW75631.1 - 3.1e-36 124.9 0.0 3e-29 101.9 0.0 2.4 2 1 0 2 2 2 2 Aminotransferase class-V Hydantoinase_B PF02538.9 EIW75632.1 - 1.6e-179 597.5 0.0 6.9e-173 575.6 0.0 2.0 2 0 0 2 2 2 2 Hydantoinase B/oxoprolinase Aminotran_1_2 PF00155.16 EIW75633.1 - 0.087 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II TOBE_2 PF08402.5 EIW75635.1 - 0.057 13.4 0.0 0.093 12.7 0.0 1.4 1 0 0 1 1 1 0 TOBE domain Dehydratase_hem PF13816.1 EIW75635.1 - 0.078 12.0 0.1 0.099 11.6 0.1 1.1 1 0 0 1 1 1 0 Haem-containing dehydratase Abhydrolase_3 PF07859.8 EIW75636.1 - 2.4e-16 59.9 0.0 2.7e-13 49.9 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW75636.1 - 2.8e-12 46.6 0.0 4.2e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW75636.1 - 5.7e-09 36.1 0.5 8.4e-09 35.6 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EIW75636.1 - 1.9e-07 30.2 0.0 4.6e-07 28.9 0.0 1.6 2 0 0 2 2 2 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 EIW75636.1 - 4e-07 29.4 0.4 0.0072 15.5 0.0 2.8 2 1 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase PF07224.6 EIW75636.1 - 7.6e-07 28.2 0.0 1.2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase COesterase PF00135.23 EIW75636.1 - 0.00026 19.8 0.5 0.0026 16.5 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family DLH PF01738.13 EIW75636.1 - 0.00069 18.9 0.0 0.02 14.2 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.7 EIW75636.1 - 0.017 13.6 0.0 0.034 12.6 0.0 1.5 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase PF00756.15 EIW75636.1 - 0.024 14.0 0.0 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 Putative esterase Lipase_3 PF01764.20 EIW75636.1 - 0.035 13.7 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Peptidase_S15 PF02129.13 EIW75636.1 - 0.065 12.6 0.0 0.15 11.4 0.0 1.6 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.5 EIW75636.1 - 0.068 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein PGAP1 PF07819.8 EIW75636.1 - 0.084 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF2424 PF10340.4 EIW75636.1 - 0.16 10.5 0.0 0.33 9.5 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2424) DUF3529 PF12046.3 EIW75637.1 - 0.1 11.6 0.2 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3529) DUF2244 PF10003.4 EIW75637.1 - 0.13 11.6 1.5 1.5 8.2 1.0 2.0 1 1 0 1 1 1 0 Integral membrane protein (DUF2244) DUF1744 PF08490.7 EIW75641.1 - 1e-110 370.0 0.0 1.5e-110 369.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EIW75641.1 - 5.2e-58 196.4 0.0 1.2e-57 195.2 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EIW75641.1 - 3.5e-20 72.2 0.0 3.5e-18 65.6 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EIW75641.1 - 9.2e-07 28.6 0.2 4.3e-06 26.3 0.2 2.0 1 1 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EIW75641.1 - 0.00092 19.0 0.0 0.0038 17.0 0.0 2.1 2 0 0 2 2 2 1 RNase_H superfamily RE_NgoFVII PF09565.5 EIW75641.1 - 0.083 11.8 0.0 0.19 10.6 0.0 1.5 1 0 0 1 1 1 0 NgoFVII restriction endonuclease MAP65_ASE1 PF03999.7 EIW75642.1 - 1.7e-50 172.2 26.0 1.6e-37 129.4 4.1 3.3 3 0 0 3 3 3 3 Microtubule associated protein (MAP65/ASE1 family) Baculo_PEP_C PF04513.7 EIW75642.1 - 0.6 9.9 4.0 3.1 7.6 0.9 3.2 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus ApoO PF09769.4 EIW75644.1 - 0.24 11.1 0.8 1 9.0 0.0 2.3 3 0 0 3 3 3 0 Apolipoprotein O Pol_alpha_B_N PF08418.5 EIW75648.1 - 0.33 10.4 3.4 0.52 9.8 2.4 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF2702 PF10863.3 EIW75649.1 - 0.11 12.2 0.0 1.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2702) CAAD PF14159.1 EIW75650.1 - 0.033 13.8 0.1 0.088 12.4 0.0 1.8 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase ThiF PF00899.16 EIW75651.1 - 1.3e-31 109.2 0.0 2e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EIW75651.1 - 0.028 14.5 0.0 0.083 12.9 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF4094 PF13334.1 EIW75652.1 - 0.045 14.1 1.3 0.16 12.4 0.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Packaging_FI PF14000.1 EIW75652.1 - 0.28 11.3 0.1 0.28 11.3 0.1 3.8 4 0 0 4 4 4 0 DNA packaging protein FI NAD_binding_8 PF13450.1 EIW75654.1 - 7.5e-06 25.8 0.0 2.5e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain EphA2_TM PF14575.1 EIW75656.1 - 0.0024 18.2 0.0 0.0044 17.3 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 EIW75656.1 - 0.0025 16.1 0.1 0.0038 15.5 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Mid2 PF04478.7 EIW75656.1 - 0.0057 16.0 0.1 0.0098 15.3 0.1 1.3 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor SKG6 PF08693.5 EIW75656.1 - 0.0075 15.5 0.7 0.027 13.7 0.5 2.0 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DAP10 PF07213.6 EIW75656.1 - 0.0077 15.9 0.5 0.036 13.8 0.2 2.2 2 0 0 2 2 2 1 DAP10 membrane protein CSF-1 PF05337.6 EIW75656.1 - 0.014 14.7 0.3 0.041 13.2 0.1 1.8 2 0 0 2 2 2 0 Macrophage colony stimulating factor-1 (CSF-1) DUF2407_C PF13373.1 EIW75656.1 - 0.02 14.8 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain TMEM154 PF15102.1 EIW75656.1 - 0.02 14.5 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family TMEM51 PF15345.1 EIW75656.1 - 0.032 13.9 0.4 0.057 13.1 0.3 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 LRR19-TM PF15176.1 EIW75656.1 - 0.047 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain VSP PF03302.8 EIW75656.1 - 0.048 12.2 2.1 0.072 11.7 1.4 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein IncA PF04156.9 EIW75656.1 - 0.097 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 IncA protein Shisa PF13908.1 EIW75656.1 - 0.16 12.1 0.1 0.37 10.9 0.1 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator FAD_binding_3 PF01494.14 EIW75657.1 - 9.5e-20 70.9 0.0 2.8e-11 43.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EIW75657.1 - 8.6e-12 44.6 0.9 1.9e-07 30.3 0.6 2.4 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW75657.1 - 1.6e-07 31.2 0.1 3.7e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIW75657.1 - 1.2e-06 28.8 0.0 0.0002 21.6 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW75657.1 - 0.0007 18.5 3.0 0.0018 17.1 0.3 2.3 2 1 1 3 3 3 1 FAD binding domain Thi4 PF01946.12 EIW75657.1 - 0.0023 17.0 0.6 0.0038 16.3 0.1 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EIW75657.1 - 0.0028 17.5 0.1 0.013 15.4 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EIW75657.1 - 0.012 14.6 0.3 0.084 11.9 0.1 2.3 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EIW75657.1 - 0.012 14.0 0.0 0.028 12.8 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein FAD_oxidored PF12831.2 EIW75657.1 - 0.014 14.5 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 EIW75657.1 - 0.065 12.0 0.1 0.087 11.6 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF2894 PF11445.3 EIW75658.1 - 7.9 6.6 11.1 1.4 9.1 4.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2894) DUF3772 PF12607.3 EIW75659.1 - 0.03 13.9 0.0 0.7 9.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) Transposase_21 PF02992.9 EIW75660.1 - 0.006 15.7 0.0 0.01 14.9 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 Transposase_21 PF02992.9 EIW75661.1 - 0.042 12.9 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 Transposase family tnp2 DUF4218 PF13960.1 EIW75662.1 - 2.6e-05 23.6 0.0 3.2e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) HIG_1_N PF04588.8 EIW75663.1 - 0.00026 20.6 0.5 0.00055 19.6 0.3 1.6 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF4231 PF14015.1 EIW75663.1 - 0.062 13.2 2.0 8.1 6.4 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Pkinase PF00069.20 EIW75665.1 - 2.9e-30 105.3 0.0 3.3e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW75665.1 - 3.3e-24 85.3 0.0 3.8e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase GMC_oxred_C PF05199.8 EIW75667.1 - 5.5e-20 72.1 0.1 1.2e-19 71.0 0.1 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EIW75667.1 - 3.1e-18 65.9 0.0 5.8e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIW75667.1 - 1.3e-09 37.4 0.3 6.9e-05 21.9 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW75667.1 - 2e-07 30.2 0.0 6.5e-05 21.9 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EIW75667.1 - 3.7e-06 26.1 0.2 0.0013 17.9 0.0 2.5 2 0 0 2 2 2 2 Thi4 family FAD_oxidored PF12831.2 EIW75667.1 - 4.5e-06 26.0 0.0 2.9e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW75667.1 - 1.7e-05 24.7 0.3 9.5e-05 22.3 0.2 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EIW75667.1 - 9.4e-05 21.0 0.1 0.00025 19.6 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 EIW75667.1 - 0.00021 20.4 0.3 0.00036 19.6 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIW75667.1 - 0.00027 20.8 0.1 0.0005 20.0 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW75667.1 - 0.0037 17.3 0.2 0.011 15.8 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIW75667.1 - 0.29 9.9 1.3 0.29 9.9 0.2 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A F-box PF00646.28 EIW75668.1 - 0.033 13.8 1.4 0.043 13.4 0.1 2.0 2 0 0 2 2 2 0 F-box domain NACHT PF05729.7 EIW75669.1 - 5.7e-11 42.3 0.0 2.4e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EIW75669.1 - 1.3e-07 31.7 0.3 3.2e-07 30.5 0.2 1.6 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.15 EIW75669.1 - 0.00014 21.5 0.0 0.00028 20.5 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase ABC_tran PF00005.22 EIW75669.1 - 0.00041 20.6 0.0 0.00091 19.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EIW75669.1 - 0.00075 19.6 0.0 0.0024 18.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EIW75669.1 - 0.0015 18.6 0.0 0.005 16.9 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_18 PF13238.1 EIW75669.1 - 0.0036 17.6 0.0 0.0089 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW75669.1 - 0.004 17.9 0.0 0.017 15.9 0.0 2.2 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.10 EIW75669.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 NTPase Zeta_toxin PF06414.7 EIW75669.1 - 0.013 14.5 0.4 0.042 12.9 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.1 EIW75669.1 - 0.015 14.8 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.17 EIW75669.1 - 0.016 14.1 0.0 0.026 13.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MobB PF03205.9 EIW75669.1 - 0.021 14.4 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.13 EIW75669.1 - 0.025 14.1 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Sigma54_activat PF00158.21 EIW75669.1 - 0.03 13.7 0.0 0.065 12.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ArgK PF03308.11 EIW75669.1 - 0.043 12.5 0.0 0.072 11.8 0.0 1.2 1 0 0 1 1 1 0 ArgK protein FtsK_SpoIIIE PF01580.13 EIW75669.1 - 0.045 13.2 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SE PF00437.15 EIW75669.1 - 0.046 12.6 0.0 0.083 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 EIW75669.1 - 0.048 13.7 0.0 0.28 11.2 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_PrkA PF08298.6 EIW75669.1 - 0.055 12.1 0.0 0.091 11.4 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain DUF258 PF03193.11 EIW75669.1 - 0.056 12.6 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EIW75669.1 - 0.062 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_30 PF13604.1 EIW75669.1 - 0.07 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain TrwB_AAD_bind PF10412.4 EIW75669.1 - 0.081 11.5 0.0 0.42 9.1 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF2075 PF09848.4 EIW75669.1 - 0.084 11.8 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EIW75669.1 - 0.11 11.8 0.0 0.26 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EIW75669.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain DDE_Tnp_1_7 PF13843.1 EIW75669.1 - 0.15 11.1 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Transposase IS4 AAA_10 PF12846.2 EIW75669.1 - 0.17 11.2 0.0 0.77 9.1 0.0 1.8 1 1 0 2 2 2 0 AAA-like domain CbiA PF01656.18 EIW75669.1 - 0.2 11.0 0.0 0.37 10.1 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RGS PF00615.14 EIW75670.1 - 3e-09 37.0 0.6 0.00036 20.6 0.0 2.7 2 1 0 2 2 2 2 Regulator of G protein signaling domain L51_S25_CI-B8 PF05047.11 EIW75671.1 - 1.3e-12 47.1 0.0 1.7e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Methyltransf_2 PF00891.13 EIW75671.1 - 0.14 11.2 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_11 PF08241.7 EIW75675.1 - 1.4e-23 83.1 0.0 2.8e-13 50.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.13 EIW75675.1 - 7.4e-13 48.1 0.0 3.7e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EIW75675.1 - 9.5e-13 48.0 0.0 9.8e-09 34.9 0.0 2.8 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EIW75675.1 - 2.2e-11 43.9 0.0 4.7e-09 36.5 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW75675.1 - 3e-10 40.0 0.0 9.4e-08 31.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIW75675.1 - 2.4e-09 37.1 0.0 0.0055 16.3 0.0 3.2 3 0 0 3 3 3 3 Hypothetical methyltransferase Methyltransf_12 PF08242.7 EIW75675.1 - 1.8e-08 34.7 0.0 1.8e-05 25.1 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EIW75675.1 - 1.4e-07 32.0 0.0 4.9e-06 27.0 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW75675.1 - 3.7e-07 30.1 0.1 0.00012 22.1 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_29 PF03141.11 EIW75675.1 - 3e-06 25.8 0.0 0.015 13.6 0.0 2.6 2 1 0 2 2 2 2 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.13 EIW75675.1 - 5.1e-05 22.5 0.0 0.00015 21.0 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EIW75675.1 - 0.00014 22.6 0.0 0.14 13.0 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIW75675.1 - 0.00018 20.5 0.0 0.00085 18.4 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_17 PF12692.2 EIW75675.1 - 0.0025 17.5 0.0 0.0045 16.6 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-methionine methyltransferase FtsJ PF01728.14 EIW75675.1 - 0.0033 17.4 0.0 0.0072 16.3 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase MetW PF07021.7 EIW75675.1 - 0.015 14.6 0.0 0.9 8.8 0.0 2.2 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW MTS PF05175.9 EIW75675.1 - 0.027 13.8 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain NPR2 PF06218.6 EIW75676.1 - 0.025 13.2 0.0 0.032 12.9 0.0 1.1 1 0 0 1 1 1 0 Nitrogen permease regulator 2 DUF3702 PF12486.3 EIW75676.1 - 0.048 13.3 0.1 0.071 12.7 0.0 1.2 1 0 0 1 1 1 0 ImpA domain protein Baculo_PEP_C PF04513.7 EIW75676.1 - 1.9 8.2 10.6 0.29 10.9 3.9 2.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus TrbL PF04610.9 EIW75676.1 - 2.2 7.9 16.5 0.099 12.3 5.9 2.2 1 1 1 2 2 2 0 TrbL/VirB6 plasmid conjugal transfer protein stn_TNFRSF12A PF12191.3 EIW75677.1 - 0.11 12.4 1.1 0.25 11.3 0.3 1.9 1 1 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain zf-RING_2 PF13639.1 EIW75678.1 - 2.2e-08 33.7 1.0 3.5e-08 33.1 0.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIW75678.1 - 0.00096 19.1 1.3 0.0016 18.3 0.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW75678.1 - 0.0047 16.5 1.1 0.0075 15.9 0.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Cas_VVA1548 PF09652.5 EIW75678.1 - 0.0093 15.9 0.0 0.014 15.4 0.0 1.2 1 0 0 1 1 1 1 Putative CRISPR-associated protein (Cas_VVA1548) zf-RING_5 PF14634.1 EIW75678.1 - 0.014 15.0 0.6 0.021 14.5 0.4 1.2 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_1 PF14446.1 EIW75678.1 - 0.05 13.3 0.6 0.077 12.7 0.4 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.24 EIW75678.1 - 0.06 13.0 0.5 0.095 12.4 0.4 1.3 1 0 0 1 1 1 0 PHD-finger zf-RING_UBOX PF13445.1 EIW75678.1 - 0.25 11.1 2.1 0.42 10.3 1.5 1.4 1 0 0 1 1 1 0 RING-type zinc-finger UQ_con PF00179.21 EIW75681.1 - 1.5e-46 157.2 0.0 1.7e-46 157.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIW75681.1 - 8.5e-05 22.3 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EIW75681.1 - 0.013 15.1 0.1 0.025 14.2 0.1 1.5 1 1 0 1 1 1 0 UEV domain RWD PF05773.17 EIW75681.1 - 0.081 12.8 0.3 0.11 12.4 0.2 1.4 1 1 0 1 1 1 0 RWD domain Skp1_POZ PF03931.10 EIW75682.1 - 3.7e-08 33.3 0.0 1.3e-07 31.5 0.0 1.9 1 1 1 2 2 2 1 Skp1 family, tetramerisation domain DUF619 PF04768.8 EIW75683.1 - 4.7e-43 146.5 0.0 7e-43 145.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EIW75683.1 - 1.3e-27 96.5 0.0 2.9e-27 95.3 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EIW75683.1 - 8.3e-19 68.0 0.0 1.8e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Amino acid kinase family Semialdhyde_dhC PF02774.13 EIW75683.1 - 0.0026 17.6 0.0 0.0046 16.8 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain GFO_IDH_MocA PF01408.17 EIW75683.1 - 0.0046 17.4 0.0 0.088 13.3 0.0 2.6 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 EIW75683.1 - 0.022 14.6 0.0 0.044 13.6 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Metallophos PF00149.23 EIW75684.1 - 7.2e-39 133.2 1.1 1.1e-38 132.6 0.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase IncFII_repA PF02387.10 EIW75684.1 - 0.097 11.8 0.4 0.16 11.1 0.3 1.2 1 0 0 1 1 1 0 IncFII RepA protein family PPP5 PF08321.7 EIW75684.1 - 0.14 12.1 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 PPP5 TPR repeat region Nop14 PF04147.7 EIW75685.1 - 3.7 5.3 25.3 6.1 4.6 17.5 1.4 1 0 0 1 1 1 0 Nop14-like family HisKA_3 PF07730.8 EIW75692.1 - 0.0056 16.9 5.4 2.5 8.4 0.3 4.8 3 1 3 6 6 6 1 Histidine kinase Reo_sigmaC PF04582.7 EIW75692.1 - 0.015 14.5 8.1 0.096 11.8 3.4 2.5 1 1 1 2 2 2 0 Reovirus sigma C capsid protein HAUS-augmin3 PF14932.1 EIW75692.1 - 0.058 12.5 2.5 0.14 11.3 1.7 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 AAA_13 PF13166.1 EIW75692.1 - 0.06 11.8 0.2 0.08 11.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain Allexi_40kDa PF05549.6 EIW75692.1 - 0.082 12.1 0.2 0.4 9.9 0.0 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein K-box PF01486.12 EIW75692.1 - 0.13 12.1 1.7 15 5.4 0.1 3.4 2 1 1 3 3 3 0 K-box region V-SNARE PF05008.10 EIW75692.1 - 0.15 12.2 7.9 0.82 9.8 0.0 3.8 2 1 2 4 4 4 0 Vesicle transport v-SNARE protein N-terminus EzrA PF06160.7 EIW75692.1 - 0.26 9.4 3.7 0.5 8.4 2.0 1.8 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Syntaxin PF00804.20 EIW75692.1 - 0.45 10.7 8.3 0.23 11.6 0.5 3.4 1 1 2 3 3 3 0 Syntaxin Sulfatase_C PF14707.1 EIW75692.1 - 0.6 10.3 2.0 1.1 9.5 0.1 2.3 3 0 0 3 3 3 0 C-terminal region of aryl-sulfatase PE_PPE_C PF12484.3 EIW75692.1 - 0.62 11.0 4.3 0.24 12.3 0.5 2.2 2 1 0 2 2 2 0 Polymorphic PE/PPE proteins C terminal HHH_8 PF14716.1 EIW75692.1 - 1.2 9.3 5.5 18 5.5 0.0 4.1 4 1 0 4 4 4 0 Helix-hairpin-helix domain TraG_N PF07916.6 EIW75692.1 - 1.3 7.3 9.5 0.04 12.3 1.6 2.0 2 1 0 3 3 3 0 TraG-like protein, N-terminal region DUF2203 PF09969.4 EIW75692.1 - 4.7 7.4 5.1 34 4.6 1.3 3.0 1 1 2 4 4 4 0 Uncharacterized conserved protein (DUF2203) Neurokinin_B PF03823.9 EIW75695.1 - 0.12 12.1 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Neurokinin B FUSC PF04632.7 EIW75696.1 - 6 5.1 10.2 0.36 9.1 0.2 2.9 2 1 1 3 3 3 0 Fusaric acid resistance protein family FUSC PF04632.7 EIW75697.1 - 0.11 10.9 2.1 0.087 11.2 0.2 1.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF3562 PF12085.3 EIW75697.1 - 0.15 11.8 0.1 20 5.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3562) CHAD PF05235.9 EIW75698.1 - 0.057 12.9 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 CHAD domain SH3_2 PF07653.12 EIW75699.1 - 0.00012 21.5 0.0 0.00017 20.9 0.0 1.2 1 0 0 1 1 1 1 Variant SH3 domain RabGAP-TBC PF00566.13 EIW75700.1 - 1.9e-28 99.4 0.0 2.6e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF4131 PF13567.1 EIW75701.1 - 9.9 5.5 7.3 0.38 10.1 0.4 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Baculo_PEP_C PF04513.7 EIW75705.1 - 0.97 9.2 5.3 1.5 8.6 3.3 1.6 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glyco_hydro_31 PF01055.21 EIW75706.1 - 6.7e-161 536.0 6.0 8.2e-161 535.7 4.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EIW75706.1 - 0.00098 18.9 0.3 0.011 15.5 0.0 2.7 2 0 0 2 2 2 1 Galactose mutarotase-like adh_short PF00106.20 EIW75707.1 - 3.2e-29 101.9 0.2 4.7e-29 101.4 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW75707.1 - 1.2e-13 51.1 0.0 2.2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIW75707.1 - 6.8e-13 48.9 0.0 9.5e-13 48.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EIW75707.1 - 9.3e-08 31.7 0.0 2.1e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW75707.1 - 3.2e-05 24.0 0.0 5e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EIW75707.1 - 0.018 14.8 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 EIW75707.1 - 0.055 12.3 0.0 0.079 11.8 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 EIW75707.1 - 0.056 12.1 0.1 0.079 11.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family IL17 PF06083.6 EIW75708.1 - 0.014 15.3 0.0 0.015 15.3 0.0 1.2 1 0 0 1 1 1 0 Interleukin-17 PTCB-BRCT PF12738.2 EIW75709.1 - 2.9e-21 75.0 2.2 5.5e-12 45.3 0.0 4.3 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 EIW75709.1 - 4.8e-19 68.2 0.0 2.3e-09 37.2 0.0 5.3 5 0 0 5 5 5 3 BRCA1 C Terminus (BRCT) domain Hydrolase_6 PF13344.1 EIW75709.1 - 0.071 13.0 0.1 0.54 10.1 0.1 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase BORG_CEP PF14957.1 EIW75710.1 - 0.043 14.7 4.3 0.049 14.5 3.0 1.1 1 0 0 1 1 1 0 Cdc42 effector RecO_N PF11967.3 EIW75710.1 - 0.064 13.1 0.3 0.086 12.7 0.2 1.3 1 0 0 1 1 1 0 Recombination protein O N terminal PGA2 PF07543.7 EIW75710.1 - 0.069 12.9 1.6 0.082 12.7 1.1 1.1 1 0 0 1 1 1 0 Protein trafficking PGA2 FLO_LFY PF01698.11 EIW75710.1 - 0.13 11.0 2.0 0.14 10.9 1.4 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DUF2215 PF10225.4 EIW75710.1 - 0.17 11.2 4.1 0.17 11.3 2.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF3899 PF13038.1 EIW75710.1 - 0.56 10.4 2.2 0.73 10.0 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) Ctr PF04145.10 EIW75710.1 - 0.82 9.7 2.4 0.91 9.5 1.7 1.1 1 0 0 1 1 1 0 Ctr copper transporter family MbtH PF03621.8 EIW75712.1 - 2.7 7.4 7.2 2.6 7.4 0.3 2.9 2 1 1 3 3 3 0 MbtH-like protein GFA PF04828.9 EIW75713.1 - 1.8e-19 69.4 0.1 3.4e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme GH3 PF03321.8 EIW75714.1 - 3.3e-38 131.5 0.0 4.9e-38 130.9 0.0 1.3 1 1 0 1 1 1 1 GH3 auxin-responsive promoter CK1gamma_C PF12605.3 EIW75715.1 - 0.29 11.7 4.0 0.72 10.4 0.1 2.0 1 1 1 2 2 2 0 Casein kinase 1 gamma C terminal 6PF2K PF01591.13 EIW75718.1 - 0.07 12.1 0.3 0.1 11.6 0.2 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase MFS_1 PF07690.11 EIW75723.1 - 5e-37 127.4 34.5 5.4e-33 114.1 19.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.4 EIW75723.1 - 0.049 14.0 1.9 0.089 13.1 0.0 2.3 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Epimerase PF01370.16 EIW75725.1 - 6.3e-10 38.8 0.0 0.0003 20.3 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIW75725.1 - 1.9e-08 33.8 0.0 2.8e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EIW75725.1 - 6.9e-06 26.3 0.0 1.2e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EIW75725.1 - 2.5e-05 23.1 0.0 0.0005 18.8 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIW75725.1 - 7e-05 22.9 0.0 0.00016 21.7 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIW75725.1 - 0.0025 16.8 0.0 0.0059 15.5 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Saccharop_dh PF03435.13 EIW75725.1 - 0.0066 15.4 0.0 0.009 15.0 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DXP_reductoisom PF02670.11 EIW75725.1 - 0.045 14.3 0.0 0.07 13.6 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Glyco_trans_1_4 PF13692.1 EIW75725.1 - 0.066 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 FA_desaturase PF00487.19 EIW75726.1 - 1.5e-15 57.3 24.7 1.5e-15 57.3 17.1 1.7 2 1 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EIW75726.1 - 6.9e-14 51.4 0.0 1.4e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SAM_2 PF07647.12 EIW75728.1 - 0.017 14.9 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SGL PF08450.7 EIW75732.1 - 2.7e-23 82.6 0.1 3.6e-23 82.2 0.1 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EIW75732.1 - 0.00056 19.9 0.0 0.0029 17.5 0.0 2.1 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 EIW75732.1 - 0.0029 17.5 0.0 0.022 14.7 0.0 2.4 2 0 0 2 2 2 1 Arylesterase NHL PF01436.16 EIW75732.1 - 0.017 15.0 1.1 1.1 9.3 0.1 2.9 2 0 0 2 2 2 0 NHL repeat SGL PF08450.7 EIW75733.1 - 1.4e-23 83.5 0.0 1.9e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EIW75733.1 - 3.1e-06 27.1 0.0 4.6e-05 23.3 0.0 2.4 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 EIW75733.1 - 0.00076 19.4 0.0 0.0034 17.3 0.0 2.1 2 0 0 2 2 2 1 Arylesterase NHL PF01436.16 EIW75733.1 - 0.03 14.2 0.9 0.26 11.3 0.0 2.6 2 0 0 2 2 2 0 NHL repeat NfeD PF01957.13 EIW75734.1 - 0.016 15.3 0.4 0.016 15.3 0.3 1.8 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF2231 PF09990.4 EIW75734.1 - 0.016 15.5 7.1 0.21 11.9 0.1 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) CopD PF05425.8 EIW75734.1 - 0.04 14.1 0.7 0.04 14.1 0.5 1.9 2 0 0 2 2 2 0 Copper resistance protein D Voltage_CLC PF00654.15 EIW75734.1 - 0.38 9.7 8.8 1.2 8.1 2.0 2.1 1 1 1 2 2 2 0 Voltage gated chloride channel Amidase PF01425.16 EIW75737.1 - 3.1e-102 342.6 0.0 5.1e-102 341.9 0.0 1.3 2 0 0 2 2 2 1 Amidase Oxidored_FMN PF00724.15 EIW75739.1 - 4.4e-92 308.6 0.0 5.4e-92 308.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Tautomerase PF01361.16 EIW75739.1 - 0.034 13.7 0.0 0.073 12.6 0.0 1.5 1 0 0 1 1 1 0 Tautomerase enzyme DUF2890 PF11081.3 EIW75744.1 - 0.0042 17.1 9.7 0.01 15.9 6.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2890) SlyX PF04102.7 EIW75744.1 - 0.12 12.7 5.1 0.36 11.2 3.5 1.8 1 0 0 1 1 1 0 SlyX ADIP PF11559.3 EIW75744.1 - 1.7 8.5 9.8 3.1 7.6 6.8 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF4337 PF14235.1 EIW75744.1 - 5.3 6.8 4.9 12 5.6 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) adh_short PF00106.20 EIW75745.1 - 6.5e-11 42.4 0.5 6.5e-11 42.4 0.3 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIW75745.1 - 0.00023 20.8 0.8 0.00042 20.0 0.2 1.7 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EIW75747.1 - 4.3e-17 62.5 0.3 7.6e-17 61.7 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW75747.1 - 1.4e-07 31.3 0.6 2e-07 30.8 0.1 1.4 2 0 0 2 2 2 1 KR domain Paf67 PF10255.4 EIW75748.1 - 7.6e-141 469.6 0.0 1.4e-140 468.7 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase I-associated factor PAF67 SNARE PF05739.14 EIW75752.1 - 5.4e-13 48.4 0.6 1.1e-12 47.4 0.4 1.5 1 0 0 1 1 1 1 SNARE domain NPV_P10 PF05531.7 EIW75752.1 - 0.083 13.1 1.2 0.37 11.0 0.3 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TMF_TATA_bd PF12325.3 EIW75752.1 - 0.19 11.4 1.0 0.33 10.7 0.1 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Glyco_hydro_12 PF01670.11 EIW75755.1 - 1e-26 93.5 2.1 2.6e-26 92.2 1.5 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 Cellulase PF00150.13 EIW75756.1 - 8.2e-28 97.4 13.3 1.1e-27 97.0 9.2 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EIW75756.1 - 1.2e-05 25.6 0.0 2.9e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 EIW75756.1 - 0.00075 18.4 0.2 0.0048 15.8 0.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 EIW75756.1 - 0.00084 18.5 0.0 0.0015 17.7 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase F-box-like PF12937.2 EIW75758.1 - 6e-06 25.8 2.6 6e-06 25.8 1.8 2.0 2 0 0 2 2 2 1 F-box-like gerPA PF10676.4 EIW75758.1 - 0.03 14.1 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 Spore germination protein gerPA/gerPF DUF4407 PF14362.1 EIW75758.1 - 0.22 10.4 1.1 0.36 9.7 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APG6 PF04111.7 EIW75758.1 - 2.3 7.1 3.9 3.3 6.6 2.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EIW75758.1 - 8.5 5.9 8.5 15 5.1 5.9 1.3 1 0 0 1 1 1 0 IncA protein Fasciclin PF02469.17 EIW75759.1 - 1.3e-28 99.6 1.8 3.7e-18 65.7 0.0 2.5 2 1 0 2 2 2 2 Fasciclin domain ABC_tran PF00005.22 EIW75760.1 - 7.6e-48 162.2 0.0 1.4e-23 83.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIW75760.1 - 2.6e-18 66.9 0.1 6.2e-06 26.3 0.0 4.3 4 0 0 4 4 4 4 AAA domain ABC2_membrane_3 PF12698.2 EIW75760.1 - 3e-17 62.6 35.4 2.5e-09 36.6 16.9 2.4 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_23 PF13476.1 EIW75760.1 - 1.1e-07 32.3 4.1 0.007 16.7 0.2 2.3 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EIW75760.1 - 2.4e-06 26.9 3.0 0.0064 16.0 0.7 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EIW75760.1 - 1.4e-05 24.4 0.4 0.56 9.3 0.0 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EIW75760.1 - 0.00076 18.6 0.4 0.33 10.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIW75760.1 - 0.011 15.8 0.4 6.6 6.8 0.0 3.3 2 2 0 2 2 2 0 AAA domain SRP54 PF00448.17 EIW75760.1 - 0.042 13.2 2.5 3.5 7.0 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_19 PF13245.1 EIW75760.1 - 0.051 13.3 2.9 8.2 6.2 0.3 2.8 2 0 0 2 2 2 0 Part of AAA domain AAA_30 PF13604.1 EIW75760.1 - 0.063 12.8 1.2 11 5.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 EIW75760.1 - 0.093 11.8 0.5 8.3 5.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.1 EIW75760.1 - 0.14 11.2 0.0 12 4.7 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain AAA_25 PF13481.1 EIW75760.1 - 0.24 10.8 1.2 16 4.7 0.1 3.4 4 0 0 4 4 4 0 AAA domain WD40 PF00400.27 EIW75762.1 - 8.9e-67 218.7 27.0 3e-10 39.5 0.1 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 EIW75762.1 - 1.1e-09 36.9 4.0 0.034 12.2 0.1 5.7 3 2 3 6 6 6 3 Nucleoporin Nup120/160 eIF2A PF08662.6 EIW75762.1 - 3.3e-06 26.9 0.3 0.0053 16.4 0.0 3.8 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EIW75762.1 - 3.9e-06 25.8 2.1 0.012 14.4 0.0 3.9 1 1 1 3 3 3 2 Nup133 N terminal like PD40 PF07676.7 EIW75762.1 - 0.023 14.3 2.0 31 4.3 0.0 5.3 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 EIW75762.1 - 0.032 13.6 0.3 3.3 7.1 0.0 2.9 3 1 0 3 3 3 0 PQQ-like domain Gmad1 PF10647.4 EIW75762.1 - 0.06 12.7 0.7 3 7.1 0.1 3.2 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain Proteasome_A_N PF10584.4 EIW75762.1 - 2.1 7.7 4.1 1.7e+02 1.6 0.0 4.1 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 EIW75763.1 - 7.3e-40 133.4 18.8 2.6e-09 36.6 0.2 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Gmad1 PF10647.4 EIW75763.1 - 2.7e-05 23.7 0.1 0.012 15.0 0.0 2.6 2 1 0 2 2 2 2 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.1 EIW75763.1 - 0.0021 17.5 2.2 0.77 9.1 0.1 3.0 1 1 0 3 3 3 1 PQQ-like domain Nbas_N PF15492.1 EIW75763.1 - 0.012 14.7 0.1 2.8 6.9 0.0 3.2 1 1 3 4 4 4 0 Neuroblastoma-amplified sequence, N terminal PQQ_3 PF13570.1 EIW75763.1 - 0.023 14.9 6.8 0.65 10.3 0.1 4.5 2 2 1 3 3 3 0 PQQ-like domain PD40 PF07676.7 EIW75763.1 - 0.024 14.3 0.0 11 5.7 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Hira PF07569.6 EIW75763.1 - 0.05 12.8 3.5 22 4.1 0.0 4.8 4 2 2 6 6 6 0 TUP1-like enhancer of split Nup160 PF11715.3 EIW75763.1 - 0.14 10.2 0.6 0.93 7.5 0.2 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 DUF3401 PF11881.3 EIW75764.1 - 0.028 13.7 2.6 0.053 12.9 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3401) F-box-like PF12937.2 EIW75768.1 - 2.2e-08 33.6 1.3 2.2e-08 33.6 0.9 2.0 2 0 0 2 2 2 1 F-box-like Myosin_tail_1 PF01576.14 EIW75768.1 - 0.1 10.3 0.8 0.13 9.9 0.6 1.0 1 0 0 1 1 1 0 Myosin tail F-box-like PF12937.2 EIW75769.1 - 9.3e-07 28.4 1.3 2.8e-06 26.9 0.9 1.9 1 0 0 1 1 1 1 F-box-like zf-C2H2 PF00096.21 EIW75770.1 - 0.033 14.5 2.0 0.1 12.9 1.4 1.8 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW75770.1 - 1.7 9.1 4.3 3.7 8.1 3.0 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger tRNA-synt_2b PF00587.20 EIW75771.1 - 1.6e-62 210.1 0.0 4.3e-62 208.7 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EIW75771.1 - 1e-21 76.6 0.0 2.6e-21 75.3 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain SSF PF00474.12 EIW75773.1 - 1.3e-15 56.9 35.7 1.3e-15 56.9 24.7 1.8 2 1 0 2 2 2 1 Sodium:solute symporter family APG12 PF04110.8 EIW75774.1 - 4.3e-21 74.8 0.0 5.5e-21 74.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 MIP-T3 PF10243.4 EIW75775.1 - 0.77 8.1 24.5 1.1 7.6 17.0 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 EIW75775.1 - 9 4.6 17.7 11 4.3 12.3 1.1 1 0 0 1 1 1 0 Daxx Family p450 PF00067.17 EIW75777.1 - 7.4e-64 215.9 0.0 9.3e-64 215.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EIW75779.1 - 4.9e-06 26.1 0.6 1.2e-05 24.8 0.4 1.8 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 EIW75781.1 - 2.8e-116 375.6 33.3 1.2e-11 44.0 0.1 13.1 13 0 0 13 13 13 12 WD domain, G-beta repeat eIF2A PF08662.6 EIW75781.1 - 1.6e-12 47.5 0.0 0.00072 19.3 0.0 5.1 2 1 4 6 6 6 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIW75781.1 - 7.9e-09 34.1 9.3 0.23 9.5 0.3 6.6 2 2 2 4 4 4 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EIW75781.1 - 2.9e-05 23.6 7.9 0.3 10.4 0.0 4.5 1 1 1 3 3 3 2 PQQ-like domain Nucleoporin_N PF08801.6 EIW75781.1 - 8.7e-05 21.4 2.4 0.043 12.5 0.4 4.4 2 1 2 4 4 4 2 Nup133 N terminal like PD40 PF07676.7 EIW75781.1 - 0.00024 20.6 2.0 4.6 7.0 0.0 6.4 8 0 0 8 8 8 1 WD40-like Beta Propeller Repeat Apc4_WD40 PF12894.2 EIW75781.1 - 0.011 15.2 0.0 3.5 7.2 0.0 3.6 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 EIW75781.1 - 0.012 13.4 0.1 11 3.6 0.0 3.3 3 1 0 3 3 3 0 IKI3 family DUF3312 PF11768.3 EIW75781.1 - 0.016 13.4 0.0 2.9 5.9 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3312) Peptidase_S9_N PF02897.10 EIW75781.1 - 0.061 11.9 0.1 1.9 6.9 0.0 2.9 3 1 0 3 3 3 0 Prolyl oligopeptidase, N-terminal beta-propeller domain DUF3484 PF11983.3 EIW75783.1 - 0.11 13.3 0.0 18 6.2 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF3484) WD40 PF00400.27 EIW75784.1 - 9.2e-131 421.6 25.1 1.2e-13 50.3 0.1 11.1 11 0 0 11 11 11 11 WD domain, G-beta repeat Nup160 PF11715.3 EIW75784.1 - 5.2e-15 54.5 12.1 0.25 9.4 0.0 9.6 1 1 5 8 8 8 6 Nucleoporin Nup120/160 eIF2A PF08662.6 EIW75784.1 - 1.3e-14 54.3 0.0 0.00051 19.7 0.0 5.2 1 1 4 6 6 6 3 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 EIW75784.1 - 8.2e-07 28.7 0.0 8.2 6.2 0.0 6.6 6 3 0 6 6 6 1 Ciliary BBSome complex subunit 2, middle region Nucleoporin_N PF08801.6 EIW75784.1 - 3.8e-06 25.9 5.6 1.3 7.6 0.0 5.7 3 3 2 5 5 5 3 Nup133 N terminal like PQQ_3 PF13570.1 EIW75784.1 - 1e-05 25.6 4.4 0.18 12.1 0.1 5.1 3 2 3 6 6 6 2 PQQ-like domain Gmad1 PF10647.4 EIW75784.1 - 0.0015 18.0 12.7 0.14 11.5 3.0 4.0 2 1 0 3 3 3 1 Lipoprotein LpqB beta-propeller domain Nbas_N PF15492.1 EIW75784.1 - 0.002 17.2 7.7 6.4 5.7 0.1 7.2 1 1 8 9 9 9 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 EIW75784.1 - 0.0039 16.8 7.8 9.6 5.9 0.0 7.0 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 EIW75784.1 - 0.0057 15.0 0.2 1.6 6.9 0.0 3.5 1 1 5 6 6 6 1 Cytochrome D1 heme domain Apc4_WD40 PF12894.2 EIW75784.1 - 0.0093 15.4 0.0 2.8 7.4 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.1 EIW75784.1 - 0.017 14.5 9.1 3 7.2 0.1 4.7 1 1 0 3 3 3 0 PQQ-like domain Me-amine-dh_H PF06433.6 EIW75784.1 - 0.03 12.9 0.0 2.7 6.5 0.0 3.5 4 0 0 4 4 4 0 Methylamine dehydrogenase heavy chain (MADH) IKI3 PF04762.7 EIW75784.1 - 0.056 11.2 0.3 2.4 5.8 0.0 3.2 2 1 0 4 4 4 0 IKI3 family DUF2415 PF10313.4 EIW75784.1 - 0.072 12.7 0.3 17 5.1 0.0 3.8 4 0 0 4 4 4 0 Uncharacterised protein domain (DUF2415) Coatomer_WDAD PF04053.9 EIW75784.1 - 0.11 11.3 0.0 1.7 7.3 0.0 2.4 1 1 1 2 2 2 0 Coatomer WD associated region WD40 PF00400.27 EIW75787.1 - 3.9e-129 416.4 26.7 2.3e-13 49.4 0.0 11.8 12 0 0 12 12 12 11 WD domain, G-beta repeat eIF2A PF08662.6 EIW75787.1 - 1.2e-09 38.1 0.0 0.05 13.3 0.0 4.5 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIW75787.1 - 5.9e-09 34.6 13.4 0.61 8.1 0.1 8.7 2 2 5 8 8 8 5 Nucleoporin Nup120/160 DUF3312 PF11768.3 EIW75787.1 - 1.3e-06 26.9 0.0 0.0055 14.9 0.0 4.3 3 1 2 5 5 5 1 Protein of unknown function (DUF3312) PD40 PF07676.7 EIW75787.1 - 2.3e-05 23.9 0.3 5 6.9 0.0 7.4 8 0 0 8 8 8 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 EIW75787.1 - 3.2e-05 22.8 9.0 0.55 8.9 0.5 6.4 2 2 2 4 4 4 2 Nup133 N terminal like IKI3 PF04762.7 EIW75787.1 - 4.5e-05 21.4 0.2 0.41 8.3 0.0 3.8 3 1 1 4 4 4 2 IKI3 family Cytochrom_D1 PF02239.11 EIW75787.1 - 0.00011 20.6 1.2 0.067 11.4 0.0 3.5 3 1 1 4 4 4 2 Cytochrome D1 heme domain Peptidase_S9_N PF02897.10 EIW75787.1 - 0.009 14.6 0.2 0.53 8.7 0.0 3.4 4 1 1 5 5 5 1 Prolyl oligopeptidase, N-terminal beta-propeller domain PQQ_3 PF13570.1 EIW75787.1 - 0.023 14.9 0.5 1.8 8.9 0.0 4.2 4 1 1 5 5 5 0 PQQ-like domain Tox-SGS PF15651.1 EIW75787.1 - 0.038 13.7 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 Salivary glad secreted protein domain toxin Coatomer_WDAD PF04053.9 EIW75787.1 - 0.074 11.8 0.0 0.65 8.7 0.0 2.5 1 1 1 2 2 2 0 Coatomer WD associated region NYD-SP28_assoc PF14775.1 EIW75787.1 - 0.93 9.2 2.5 41 3.9 0.0 4.5 6 0 0 6 6 6 0 Sperm tail C-terminal domain PBP PF01161.15 EIW75789.1 - 1.6e-13 50.7 0.0 5.6e-13 48.9 0.0 1.8 2 1 0 2 2 2 1 Phosphatidylethanolamine-binding protein Pyridox_oxidase PF01243.15 EIW75790.1 - 0.034 14.1 0.0 6.4 6.8 0.0 3.3 2 2 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase WD40 PF00400.27 EIW75792.1 - 3.3e-81 264.5 51.9 2.4e-10 39.8 0.3 13.3 13 0 0 13 13 13 11 WD domain, G-beta repeat eIF2A PF08662.6 EIW75792.1 - 1.3e-10 41.2 0.0 0.0013 18.5 0.0 5.0 3 2 2 5 5 5 3 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EIW75792.1 - 2e-06 27.4 0.9 0.29 10.5 0.0 4.9 3 2 0 3 3 3 2 PQQ-like domain Nup160 PF11715.3 EIW75792.1 - 0.00032 18.9 11.6 4.8 5.1 0.1 7.6 6 3 3 9 9 9 2 Nucleoporin Nup120/160 PD40 PF07676.7 EIW75792.1 - 0.0018 17.8 1.7 83 3.0 0.0 6.5 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 EIW75792.1 - 0.0035 15.6 0.0 4.6 5.3 0.0 3.5 2 1 0 4 4 4 2 Protein of unknown function (DUF3312) Nucleoporin_N PF08801.6 EIW75792.1 - 0.0092 14.7 0.9 8.2 5.0 0.0 4.0 2 2 1 3 3 3 1 Nup133 N terminal like MRJP PF03022.11 EIW75792.1 - 0.023 13.8 0.0 0.16 11.1 0.0 2.4 3 0 0 3 3 3 0 Major royal jelly protein Cytochrom_D1 PF02239.11 EIW75792.1 - 0.036 12.3 0.5 3.8 5.7 0.0 3.8 3 1 1 4 4 4 0 Cytochrome D1 heme domain DPPIV_N PF00930.16 EIW75792.1 - 0.14 10.6 0.1 8 4.9 0.0 3.8 3 2 1 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PQQ_3 PF13570.1 EIW75792.1 - 0.29 11.4 13.0 9.1 6.7 0.1 6.6 8 0 0 8 8 8 0 PQQ-like domain Proteasome_A_N PF10584.4 EIW75792.1 - 0.52 9.6 8.4 4.7 6.6 0.0 5.4 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature F-box-like PF12937.2 EIW75793.1 - 2.4e-07 30.3 0.2 7.5e-07 28.7 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EIW75793.1 - 0.0057 16.3 0.6 2.3 8.0 0.1 3.2 2 1 0 2 2 2 2 Leucine rich repeat Glyco_hydro_31 PF01055.21 EIW75794.1 - 7.7e-158 525.9 6.9 9.4e-158 525.6 4.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EIW75794.1 - 0.0058 16.4 0.4 0.028 14.2 0.0 2.4 2 0 0 2 2 2 1 Galactose mutarotase-like EBP PF05241.7 EIW75795.1 - 2.7e-10 39.5 11.4 3.1e-10 39.4 7.9 1.0 1 0 0 1 1 1 1 Emopamil binding protein Helicase_C PF00271.26 EIW75800.1 - 6.1e-10 38.8 0.0 1.8e-09 37.3 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIW75800.1 - 1.9e-05 24.2 0.0 9.6e-05 21.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Yip1 PF04893.12 EIW75801.1 - 0.051 13.0 13.3 0.015 14.8 6.8 1.7 1 1 1 2 2 2 0 Yip1 domain 60KD_IMP PF02096.15 EIW75801.1 - 0.053 13.1 1.4 0.099 12.2 1.0 1.6 1 1 0 1 1 1 0 60Kd inner membrane protein DUF3112 PF11309.3 EIW75801.1 - 0.98 9.1 5.9 0.53 10.0 2.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3112) Glyco_hydro_18 PF00704.23 EIW75802.1 - 4.1e-44 151.4 0.8 5e-44 151.1 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.3 EIW75802.1 - 0.088 12.4 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) WD40 PF00400.27 EIW75804.1 - 6.3e-103 333.3 49.9 1.7e-09 37.2 0.6 14.3 14 0 0 14 14 14 14 WD domain, G-beta repeat Nup160 PF11715.3 EIW75804.1 - 2.2e-09 36.0 10.7 0.041 12.0 0.0 7.4 1 1 3 6 6 6 3 Nucleoporin Nup120/160 eIF2A PF08662.6 EIW75804.1 - 1.9e-08 34.2 0.0 0.0067 16.1 0.0 5.8 2 2 4 7 7 7 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EIW75804.1 - 2.3e-05 23.3 4.0 0.078 11.7 0.1 4.4 2 2 2 4 4 4 2 Nup133 N terminal like PD40 PF07676.7 EIW75804.1 - 0.00065 19.3 4.5 24 4.7 0.0 7.5 8 0 0 8 8 8 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 EIW75804.1 - 0.047 11.9 0.2 1.2 7.3 0.0 3.1 2 2 2 4 4 4 0 Cytochrome D1 heme domain Pkinase PF00069.20 EIW75805.1 - 1.9e-69 233.6 0.0 2.3e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW75805.1 - 1.2e-36 126.1 0.0 1.5e-36 125.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW75805.1 - 1.8e-05 23.8 0.0 2.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EIW75805.1 - 0.00035 19.9 0.0 0.00061 19.1 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EIW75805.1 - 0.093 11.7 0.1 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 EIW75806.1 - 1.1e-140 453.0 29.1 1.7e-11 43.4 0.0 13.1 13 0 0 13 13 13 13 WD domain, G-beta repeat eIF2A PF08662.6 EIW75806.1 - 1.4e-11 44.4 0.0 0.0083 15.8 0.0 4.7 1 1 4 5 5 5 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIW75806.1 - 4.7e-11 41.5 15.8 0.052 11.6 0.0 9.3 3 3 2 8 8 8 4 Nucleoporin Nup120/160 PD40 PF07676.7 EIW75806.1 - 8.5e-08 31.6 3.4 4.4 7.0 0.0 8.9 11 0 0 11 11 11 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 EIW75806.1 - 2.6e-06 26.4 8.4 0.98 8.0 0.1 6.5 1 1 1 5 5 5 2 Nup133 N terminal like DUF3312 PF11768.3 EIW75806.1 - 0.00058 18.2 0.1 0.33 9.1 0.1 3.1 4 0 0 4 4 4 2 Protein of unknown function (DUF3312) PQQ_3 PF13570.1 EIW75806.1 - 0.0015 18.7 9.4 0.77 10.1 0.2 5.9 5 3 1 6 6 6 2 PQQ-like domain IKI3 PF04762.7 EIW75806.1 - 0.0057 14.5 0.1 1.4 6.6 0.1 3.7 2 1 1 3 3 3 1 IKI3 family PQQ_2 PF13360.1 EIW75806.1 - 0.0077 15.7 7.3 0.65 9.4 1.6 4.8 1 1 2 3 3 3 2 PQQ-like domain DUF1914 PF08932.5 EIW75806.1 - 0.029 14.4 0.2 0.49 10.4 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF1914) Cytochrom_D1 PF02239.11 EIW75806.1 - 0.03 12.6 0.1 8.6 4.5 0.0 3.2 2 1 0 3 3 3 0 Cytochrome D1 heme domain SdiA-regulated PF06977.6 EIW75806.1 - 0.069 12.0 0.0 3 6.7 0.0 2.9 2 1 1 3 3 3 0 SdiA-regulated Coatomer_WDAD PF04053.9 EIW75806.1 - 0.14 10.9 0.0 0.6 8.8 0.0 2.0 2 0 0 2 2 2 0 Coatomer WD associated region WD40 PF00400.27 EIW75808.1 - 1.6e-92 300.3 33.9 1.3e-12 47.0 0.1 11.5 11 0 0 11 11 11 10 WD domain, G-beta repeat eIF2A PF08662.6 EIW75808.1 - 2.1e-12 47.1 0.0 7.4e-05 22.5 0.0 4.2 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIW75808.1 - 5.8e-07 28.0 13.4 0.032 12.3 0.1 7.5 2 2 5 7 7 7 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIW75808.1 - 0.00017 20.5 0.3 0.049 12.3 0.0 2.8 1 1 0 2 2 2 2 Nup133 N terminal like PD40 PF07676.7 EIW75808.1 - 0.0034 17.0 3.2 7 6.4 0.0 4.6 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 EIW75808.1 - 0.26 10.6 1.4 28 4.1 0.0 4.1 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Glyco_hydro_31 PF01055.21 EIW75810.1 - 6.1e-123 410.9 3.0 4.6e-116 388.2 0.1 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EIW75810.1 - 0.00011 21.9 1.0 0.0003 20.5 0.0 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like FMO-like PF00743.14 EIW75811.1 - 3.9e-15 55.0 0.0 9.5e-13 47.1 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EIW75811.1 - 5.3e-15 56.0 0.0 1.4e-14 54.6 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW75811.1 - 8.4e-10 38.0 0.0 0.055 12.3 0.0 4.1 3 1 1 4 4 4 4 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EIW75811.1 - 1.9e-07 31.3 0.3 0.0078 16.5 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW75811.1 - 2.1e-06 27.6 0.0 5.1e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EIW75811.1 - 0.00032 20.5 0.3 0.0011 18.7 0.0 2.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EIW75811.1 - 0.0068 15.3 0.3 0.026 13.4 0.0 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase DUF2325 PF10087.4 EIW75811.1 - 0.04 13.7 0.1 5.1 6.9 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2325) Pyr_redox_2 PF07992.9 EIW75811.1 - 0.043 13.6 0.0 0.2 11.5 0.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIW75811.1 - 0.094 11.7 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EIW75811.1 - 0.11 11.4 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Spermine_synth PF01564.12 EIW75811.1 - 0.13 11.2 0.0 0.22 10.4 0.0 1.3 1 0 0 1 1 1 0 Spermine/spermidine synthase AA_permease PF00324.16 EIW75812.1 - 3.1e-114 381.9 38.8 3.9e-114 381.6 26.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIW75812.1 - 4.4e-34 117.7 42.7 5.4e-34 117.4 29.6 1.0 1 0 0 1 1 1 1 Amino acid permease PNP_UDP_1 PF01048.15 EIW75813.1 - 1.9e-26 92.4 0.0 2.8e-26 91.9 0.0 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Glyco_tran_WecB PF03808.8 EIW75813.1 - 0.033 13.5 0.0 0.061 12.7 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family HMG_box PF00505.14 EIW75814.1 - 3.2e-16 59.3 0.6 5.2e-16 58.6 0.4 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIW75814.1 - 6e-13 48.9 0.3 1.3e-12 47.8 0.2 1.5 1 0 0 1 1 1 1 HMG-box domain DUF1014 PF06244.7 EIW75814.1 - 0.018 15.2 0.0 0.031 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1014) HAD_2 PF13419.1 EIW75815.1 - 1.2e-23 84.1 0.0 1.9e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIW75815.1 - 7.1e-08 32.0 0.1 1.2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EIW75815.1 - 0.00028 21.3 0.0 0.00053 20.4 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DnaB_bind PF10410.4 EIW75815.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 DnaB-helicase binding domain of primase Glyco_hydro_61 PF03443.9 EIW75816.1 - 3.5e-49 167.5 0.7 4.4e-49 167.2 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.9 EIW75818.1 - 1.2e-50 172.3 0.1 1.7e-50 171.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_31 PF01055.21 EIW75819.1 - 1.4e-149 498.7 1.9 1.7e-149 498.4 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EIW75819.1 - 0.00031 20.5 0.1 0.00083 19.1 0.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like Dimer_Tnp_hAT PF05699.9 EIW75820.1 - 5.5e-08 32.3 0.0 6.1e-08 32.1 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region LT-IIB PF06453.6 EIW75820.1 - 0.057 13.1 0.1 0.066 12.8 0.1 1.0 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) MANEC PF07502.9 EIW75822.1 - 0.052 13.5 0.9 0.085 12.8 0.7 1.3 1 0 0 1 1 1 0 MANEC domain WD40 PF00400.27 EIW75825.1 - 3e-103 334.4 36.5 6.5e-11 41.6 0.3 11.1 11 0 0 11 11 11 11 WD domain, G-beta repeat eIF2A PF08662.6 EIW75825.1 - 8.9e-13 48.3 0.0 0.00037 20.2 0.0 4.5 1 1 4 5 5 5 3 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EIW75825.1 - 2.9e-10 39.9 0.6 0.014 14.8 0.0 4.8 1 1 1 3 3 3 2 PQQ-like domain SGL PF08450.7 EIW75825.1 - 8.9e-06 25.2 0.1 0.014 14.7 0.0 3.3 1 1 2 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region Gmad1 PF10647.4 EIW75825.1 - 1.2e-05 24.8 0.1 0.92 8.8 0.0 4.0 2 2 2 4 4 4 3 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 EIW75825.1 - 1.9e-05 24.2 3.2 35 4.2 0.0 8.8 11 0 0 11 11 11 0 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 EIW75825.1 - 1.9e-05 23.5 1.4 2.2 6.9 0.0 4.4 3 2 1 4 4 4 2 Nup133 N terminal like Nup160 PF11715.3 EIW75825.1 - 3.5e-05 22.1 10.2 0.89 7.6 0.1 6.3 3 2 3 6 6 6 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 EIW75825.1 - 9.2e-05 21.6 3.2 2.6 7.0 0.0 7.0 3 2 7 10 10 10 1 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.11 EIW75825.1 - 0.00014 20.2 1.4 0.26 9.5 0.0 4.0 2 2 3 5 5 5 2 Cytochrome D1 heme domain PQQ_3 PF13570.1 EIW75825.1 - 0.00045 20.3 6.4 34 4.9 0.0 7.0 7 2 1 8 8 8 0 PQQ-like domain IKI3 PF04762.7 EIW75825.1 - 0.11 10.2 0.5 3.6 5.2 0.0 3.1 3 2 1 4 4 4 0 IKI3 family F-box-like PF12937.2 EIW75827.1 - 2.8e-08 33.3 3.6 2.1e-07 30.5 2.9 2.3 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 EIW75827.1 - 0.036 13.7 4.2 0.11 12.2 2.9 1.8 1 1 0 1 1 1 0 F-box-like domain Peptidase_C48 PF02902.14 EIW75828.1 - 7.8e-07 28.9 0.0 1.5e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain zf-RVT PF13966.1 EIW75829.1 - 2.5e-05 24.5 0.0 3.5e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Oxysterol_BP PF01237.13 EIW75830.1 - 1.8e-116 388.5 0.0 2.6e-116 387.9 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein Ank_5 PF13857.1 EIW75830.1 - 2.1e-14 53.2 1.8 7.8e-08 32.3 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIW75830.1 - 3.6e-14 52.8 0.0 2.4e-11 43.8 0.0 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EIW75830.1 - 1.4e-13 49.8 2.0 0.00016 21.3 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EIW75830.1 - 1e-12 48.2 0.4 2.5e-08 34.1 0.1 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) PH PF00169.24 EIW75830.1 - 1e-11 44.9 0.0 1.8e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 PH domain Ank_3 PF13606.1 EIW75830.1 - 9.5e-11 40.8 0.5 0.0089 16.1 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat PH_11 PF15413.1 EIW75830.1 - 2.3e-05 24.5 0.1 6e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EIW75830.1 - 0.00044 20.2 0.7 0.0066 16.4 0.0 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain AA_permease PF00324.16 EIW75831.1 - 4.5e-102 341.8 31.6 5.3e-102 341.6 21.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIW75831.1 - 4.7e-30 104.4 36.0 5.7e-30 104.1 24.9 1.0 1 0 0 1 1 1 1 Amino acid permease Grp1_Fun34_YaaH PF01184.14 EIW75832.1 - 4.6e-73 244.9 13.3 5.9e-73 244.6 9.2 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family HAD_2 PF13419.1 EIW75834.1 - 4e-22 79.2 0.2 5.8e-22 78.7 0.1 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIW75834.1 - 0.00011 22.6 0.0 0.0004 20.8 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIW75834.1 - 0.00019 21.0 0.0 0.00036 20.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like zf-4CXXC_R1 PF10497.4 EIW75835.1 - 2.6e-09 37.1 9.2 4.9e-09 36.2 6.4 1.3 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 TF_Zn_Ribbon PF08271.7 EIW75835.1 - 0.15 11.4 2.3 0.41 10.0 1.6 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding NAP PF00956.13 EIW75836.1 - 2.4e-78 262.6 2.1 3.7e-78 262.0 1.5 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) AIG2 PF06094.7 EIW75837.1 - 0.0003 21.2 0.0 0.00048 20.5 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family AIG2_2 PF13772.1 EIW75837.1 - 0.0097 16.0 0.0 0.41 10.8 0.0 2.5 3 0 0 3 3 3 1 AIG2-like family Glyco_hydro_31 PF01055.21 EIW75838.1 - 2.2e-160 534.3 7.5 2.7e-160 534.0 5.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EIW75838.1 - 0.00086 19.1 0.7 0.0023 17.7 0.0 2.2 2 0 0 2 2 2 1 Galactose mutarotase-like WD40 PF00400.27 EIW75839.1 - 2e-63 208.1 30.6 5.1e-11 42.0 0.5 7.9 7 1 1 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EIW75839.1 - 1.8e-08 32.9 13.7 0.035 12.2 0.1 5.5 2 1 4 6 6 6 4 Nucleoporin Nup120/160 eIF2A PF08662.6 EIW75839.1 - 5.7e-07 29.4 0.1 0.024 14.3 0.0 4.0 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EIW75839.1 - 0.00053 18.8 0.1 0.22 10.2 0.0 3.2 1 1 0 3 3 3 1 Nup133 N terminal like PD40 PF07676.7 EIW75839.1 - 0.15 11.7 1.3 11 5.8 0.0 3.5 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat FG-GAP PF01839.18 EIW75839.1 - 0.16 11.7 1.3 0.46 10.2 0.3 2.3 2 0 0 2 2 2 0 FG-GAP repeat Proteasome_A_N PF10584.4 EIW75839.1 - 0.46 9.8 4.1 34 3.8 0.0 4.9 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature dCMP_cyt_deam_1 PF00383.17 EIW75840.1 - 3.8e-19 68.2 0.1 9.7e-18 63.7 0.1 2.1 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EIW75840.1 - 5.7e-05 22.8 0.0 0.00011 21.8 0.0 1.6 1 1 0 1 1 1 1 APOBEC-like N-terminal domain MafB19-deam PF14437.1 EIW75840.1 - 0.0022 17.6 0.0 0.003 17.1 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase XOO_2897-deam PF14440.1 EIW75840.1 - 0.0034 17.0 0.0 0.0052 16.4 0.0 1.3 1 0 0 1 1 1 1 Xanthomonas XOO_2897-like deaminase Bd3614-deam PF14439.1 EIW75840.1 - 0.21 11.4 1.7 0.79 9.5 1.2 1.9 1 1 0 1 1 1 0 Bd3614-like deaminase HSP70 PF00012.15 EIW75841.1 - 8.8e-59 198.9 4.1 1.3e-42 145.6 0.1 3.3 3 0 0 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.8 EIW75841.1 - 2.1e-07 29.8 0.1 1.5e-06 27.1 0.0 2.3 1 1 0 1 1 1 1 MreB/Mbl protein UPF0175 PF03683.8 EIW75841.1 - 2.1 7.8 4.3 0.94 8.9 0.3 2.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0175) UCH PF00443.24 EIW75842.1 - 3.7e-41 141.0 0.0 5.2e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EIW75842.1 - 7.8e-23 79.6 0.3 1.2e-11 44.0 0.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.14 EIW75842.1 - 1e-21 76.7 17.6 1.3e-17 63.6 1.7 3.3 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EIW75842.1 - 8.1e-10 38.6 0.0 2.7e-07 30.3 0.0 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.1 EIW75842.1 - 0.071 12.6 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain WD40 PF00400.27 EIW75843.1 - 3.3e-91 296.2 34.8 1.5e-11 43.6 0.3 11.2 11 0 0 11 11 11 11 WD domain, G-beta repeat eIF2A PF08662.6 EIW75843.1 - 1.3e-09 38.0 0.0 0.011 15.4 0.0 4.7 2 2 3 5 5 5 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIW75843.1 - 1e-06 27.1 7.7 0.66 8.0 0.0 6.1 4 3 1 6 6 6 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EIW75843.1 - 6.8e-05 21.3 0.2 2.3 6.4 0.0 4.1 2 2 2 4 4 4 3 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 EIW75843.1 - 8e-05 21.8 3.9 3.2 7.1 0.0 6.8 7 0 0 7 7 7 1 Proteasome subunit A N-terminal signature Nucleoporin_N PF08801.6 EIW75843.1 - 0.00026 19.8 4.0 0.68 8.6 0.2 4.8 4 3 0 4 4 4 1 Nup133 N terminal like Nbas_N PF15492.1 EIW75843.1 - 0.00048 19.3 0.8 8.2 5.4 0.0 5.6 5 2 2 7 7 7 1 Neuroblastoma-amplified sequence, N terminal MMS1_N PF10433.4 EIW75843.1 - 0.0013 16.9 0.0 0.2 9.7 0.0 2.5 2 1 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF3312 PF11768.3 EIW75843.1 - 0.0099 14.1 0.1 1.1 7.4 0.0 3.3 3 1 1 4 4 4 1 Protein of unknown function (DUF3312) PD40 PF07676.7 EIW75843.1 - 0.012 15.2 10.1 3.7 7.3 0.0 7.0 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 EIW75843.1 - 0.018 14.5 0.5 7.5 5.9 0.0 3.7 1 1 1 2 2 2 0 PQQ-like domain DPPIV_N PF00930.16 EIW75843.1 - 0.087 11.3 0.0 10 4.5 0.0 3.6 3 1 0 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region WD40 PF00400.27 EIW75845.1 - 4.6e-105 340.1 45.8 4.4e-12 45.3 0.4 16.5 16 0 0 16 16 16 15 WD domain, G-beta repeat eIF2A PF08662.6 EIW75845.1 - 5.5e-15 55.5 0.1 0.00057 19.6 0.0 6.6 3 3 4 7 7 7 5 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EIW75845.1 - 1.6e-06 26.6 3.4 0.61 8.3 0.0 5.3 4 3 2 6 6 6 3 Cytochrome D1 heme domain Nup160 PF11715.3 EIW75845.1 - 1.3e-05 23.5 7.5 1.5 6.8 0.0 6.4 4 3 1 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIW75845.1 - 3.1e-05 22.9 4.4 0.088 11.5 0.8 5.7 5 1 0 5 5 5 1 Nup133 N terminal like PD40 PF07676.7 EIW75845.1 - 0.00013 21.5 3.9 21 4.8 0.0 7.7 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EIW75845.1 - 0.00025 20.2 1.2 13 4.8 0.0 5.7 5 2 1 6 6 6 0 Neuroblastoma-amplified sequence, N terminal UBA PF00627.26 EIW75845.1 - 0.00053 19.7 0.5 0.7 9.8 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain Hira PF07569.6 EIW75845.1 - 0.0062 15.7 0.0 10 5.2 0.0 4.4 4 1 1 5 5 5 1 TUP1-like enhancer of split PQQ_2 PF13360.1 EIW75845.1 - 0.0082 15.6 5.1 2.7 7.4 0.1 4.4 3 3 0 4 4 4 1 PQQ-like domain Proteasome_A_N PF10584.4 EIW75845.1 - 0.0093 15.2 2.5 22 4.4 0.0 6.2 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature DUF3312 PF11768.3 EIW75845.1 - 0.029 12.5 0.1 0.67 8.1 0.0 3.1 4 1 1 5 5 5 0 Protein of unknown function (DUF3312) Rep_fac-A_C PF08646.5 EIW75845.1 - 0.16 11.7 0.0 56 3.4 0.0 3.2 3 0 0 3 3 3 0 Replication factor-A C terminal domain adh_short PF00106.20 EIW75847.1 - 1.2e-26 93.5 0.2 1.6e-26 93.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW75847.1 - 9.9e-12 44.8 0.1 1.5e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIW75847.1 - 2e-10 40.8 0.0 2.7e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIW75847.1 - 3.3e-05 23.9 0.1 6.2e-05 23.0 0.1 1.6 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EIW75848.1 - 1.3e-18 67.4 0.0 1.8e-18 67.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW75848.1 - 4.6e-12 46.2 0.0 5.8e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW75848.1 - 5.4e-05 22.9 0.0 9.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIW75848.1 - 0.049 13.6 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Aldo_ket_red PF00248.16 EIW75849.1 - 5e-43 146.9 0.0 5.7e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EIW75850.1 - 5.8e-41 140.1 0.0 6.6e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.20 EIW75851.1 - 8.7e-27 94.0 0.0 1.2e-26 93.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW75851.1 - 5.5e-13 49.2 0.0 8.7e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW75851.1 - 8.1e-11 41.9 0.1 6.8e-10 38.8 0.1 2.0 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIW75851.1 - 2e-07 31.2 0.0 7.5e-07 29.3 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EIW75851.1 - 5.5e-05 22.7 0.0 9.3e-05 21.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EIW75851.1 - 0.00099 18.8 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3326 PF11805.3 EIW75851.1 - 0.043 12.5 0.0 0.057 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) SHR3_chaperone PF08229.6 EIW75854.1 - 0.0078 15.1 1.2 0.0078 15.1 0.8 1.9 2 1 1 3 3 3 1 ER membrane protein SH3 Ldr_toxin PF13940.1 EIW75854.1 - 0.067 12.9 7.6 0.31 10.8 0.0 3.0 3 0 0 3 3 3 0 Toxin Ldr, type I toxin-antitoxin system DUF3353 PF11833.3 EIW75854.1 - 0.55 9.6 0.0 0.55 9.6 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3353) Trp_halogenase PF04820.9 EIW75856.1 - 7.5e-27 94.0 0.5 3.7e-12 45.6 0.0 3.2 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 EIW75856.1 - 1.8e-08 33.8 0.0 3.5e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIW75856.1 - 3.9e-06 26.8 0.0 7.9e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW75856.1 - 2.2e-05 24.3 0.9 6.7e-05 22.8 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIW75856.1 - 4.2e-05 22.6 0.3 0.00021 20.3 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW75856.1 - 6.2e-05 22.0 0.1 0.00014 20.8 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EIW75856.1 - 9.3e-05 21.6 0.1 0.00018 20.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EIW75856.1 - 0.00034 19.2 0.1 0.00053 18.5 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EIW75856.1 - 0.0035 16.2 0.1 0.0071 15.2 0.1 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EIW75856.1 - 0.009 16.0 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW75856.1 - 0.014 14.5 0.0 0.046 12.7 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 EIW75856.1 - 0.1 13.0 0.3 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase BING4CT PF08149.6 EIW75857.1 - 7.2e-33 111.9 0.0 2.3e-31 107.1 0.0 2.7 2 0 0 2 2 2 1 BING4CT (NUC141) domain WD40 PF00400.27 EIW75857.1 - 0.00025 20.8 0.0 0.0029 17.4 0.0 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EIW75857.1 - 0.014 15.1 0.2 0.66 9.6 0.0 2.9 4 0 0 4 4 4 0 Transcription factor IIIC subunit delta N-term Gb3_synth PF04572.7 EIW75857.1 - 0.19 11.4 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 Alpha 1,4-glycosyltransferase conserved region F-box-like PF12937.2 EIW75858.1 - 9.3e-10 38.0 3.7 3.5e-09 36.2 2.6 2.1 1 0 0 1 1 1 1 F-box-like AtpR PF12966.2 EIW75858.1 - 0.11 12.7 0.1 0.27 11.4 0.1 1.6 1 0 0 1 1 1 0 N-ATPase, AtpR subunit LRR_8 PF13855.1 EIW75858.1 - 0.17 11.6 4.1 4.5 7.1 0.4 3.2 3 0 0 3 3 3 0 Leucine rich repeat Pro-kuma_activ PF09286.6 EIW75859.1 - 6.5e-38 129.9 0.1 1.2e-37 129.1 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIW75859.1 - 3.8e-05 22.9 2.7 3.8e-05 22.9 1.9 2.1 2 0 0 2 2 2 1 Subtilase family adh_short PF00106.20 EIW75860.1 - 2.4e-29 102.3 0.2 3.2e-29 101.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW75860.1 - 7.4e-14 52.0 0.0 9.8e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW75860.1 - 1.7e-13 50.6 0.0 2.6e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIW75860.1 - 4.3e-07 30.1 0.2 1.4e-06 28.4 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW75860.1 - 0.001 18.5 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIW75860.1 - 0.0013 17.9 0.0 0.0026 17.0 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Eno-Rase_NADH_b PF12242.3 EIW75860.1 - 0.0019 17.9 0.2 0.018 14.8 0.1 2.4 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyoxal_oxid_N PF07250.6 EIW75862.1 - 2.2e-37 128.4 0.0 9.5e-36 123.0 0.0 2.7 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EIW75862.1 - 4.9e-22 77.8 0.5 1.3e-21 76.5 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Herpes_gE PF02480.11 EIW75862.1 - 0.0048 15.2 0.1 0.0076 14.5 0.1 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Kelch_4 PF13418.1 EIW75862.1 - 0.049 13.4 4.8 2 8.2 0.1 3.9 4 0 0 4 4 4 0 Galactose oxidase, central domain Adeno_E3_CR2 PF02439.10 EIW75862.1 - 0.097 12.2 0.4 0.17 11.4 0.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 YL1_C PF08265.6 EIW75863.1 - 2.1e-15 55.9 0.2 3.2e-15 55.3 0.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain zf-HIT PF04438.11 EIW75863.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 HIT zinc finger BPD_transp_2 PF02653.11 EIW75865.1 - 0.0027 16.7 13.3 0.0027 16.7 9.2 1.8 2 1 0 2 2 2 1 Branched-chain amino acid transport system / permease component DUF3816 PF12822.2 EIW75865.1 - 7.1 6.4 22.2 14 5.5 9.9 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3816) Aldo_ket_red PF00248.16 EIW75866.1 - 3.3e-40 137.7 0.0 4e-40 137.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family adh_short PF00106.20 EIW75867.1 - 8.5e-26 90.8 0.0 1.2e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW75867.1 - 6.9e-14 52.1 0.0 9.7e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW75867.1 - 4.8e-11 42.6 0.0 8.1e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW75867.1 - 3.6e-05 23.3 0.0 7.2e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW75867.1 - 0.0032 17.5 0.0 0.0069 16.4 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EIW75867.1 - 0.012 14.5 0.0 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 EIW75868.1 - 4.4e-28 98.2 0.1 5.9e-28 97.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW75868.1 - 1.1e-15 58.1 0.0 1.7e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW75868.1 - 1.2e-13 51.1 0.0 1.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW75868.1 - 1.8e-05 24.3 0.0 3.4e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW75868.1 - 2.5e-05 24.3 0.0 4.7e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EIW75868.1 - 0.019 13.8 0.0 0.034 13.0 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 EIW75868.1 - 0.023 13.3 0.0 0.033 12.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Eno-Rase_NADH_b PF12242.3 EIW75868.1 - 0.3 10.8 1.7 0.58 9.9 0.0 2.3 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase LRR_7 PF13504.1 EIW75869.1 - 0.78 10.2 5.8 53 4.6 0.0 5.0 5 0 0 5 5 5 0 Leucine rich repeat adh_short PF00106.20 EIW75872.1 - 3e-28 98.8 0.9 4.8e-28 98.1 0.3 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIW75872.1 - 1.5e-12 47.5 0.1 2.6e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIW75872.1 - 3.7e-11 43.2 0.0 5e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EIW75872.1 - 1.5e-07 31.1 0.1 3.5e-07 29.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW75872.1 - 2.4e-05 24.3 0.1 3.8e-05 23.7 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EIW75872.1 - 0.028 13.3 0.0 0.04 12.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 EIW75872.1 - 0.066 11.9 0.1 0.092 11.4 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Pro-kuma_activ PF09286.6 EIW75873.1 - 4.3e-39 133.7 0.1 8.7e-39 132.8 0.1 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIW75873.1 - 1.2e-05 24.5 4.4 1.2e-05 24.5 3.1 1.8 2 0 0 2 2 2 1 Subtilase family XPG_I PF00867.13 EIW75874.1 - 1.9e-20 72.7 0.0 3.3e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 EIW75874.1 - 0.0031 17.0 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 XPG domain containing XPG_N PF00752.12 EIW75874.1 - 0.07 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 XPG N-terminal domain DDE_1 PF03184.14 EIW75876.1 - 4.6e-05 22.6 0.0 5.6e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIW75876.1 - 0.001 18.8 0.0 0.0014 18.3 0.0 1.5 1 1 0 1 1 1 1 DDE superfamily endonuclease AA_permease PF00324.16 EIW75877.1 - 1.6e-116 389.5 33.2 1.9e-116 389.2 23.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIW75877.1 - 6.6e-35 120.4 36.0 8.1e-35 120.1 24.9 1.1 1 0 0 1 1 1 1 Amino acid permease Peptidase_M20 PF01546.23 EIW75878.1 - 6.5e-10 38.8 0.3 8.9e-10 38.3 0.2 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIW75878.1 - 0.034 13.8 0.2 0.082 12.6 0.0 1.7 2 0 0 2 2 2 0 Peptidase dimerisation domain p450 PF00067.17 EIW75879.1 - 3.9e-60 203.6 0.0 8.7e-60 202.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 EIW75880.1 - 0.00074 18.7 0.0 0.0014 17.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW75880.1 - 0.014 14.4 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase BA14K PF07886.6 EIW75880.1 - 0.15 11.7 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 BA14K-like protein NAD_binding_10 PF13460.1 EIW75881.1 - 8.1e-06 25.9 0.2 0.00025 21.0 0.1 2.6 2 1 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIW75881.1 - 0.0019 17.1 0.6 0.018 14.0 0.1 2.2 2 1 0 2 2 2 1 Male sterility protein DUF605 PF04652.11 EIW75881.1 - 0.002 17.6 11.7 0.0022 17.4 8.1 1.1 1 0 0 1 1 1 1 Vta1 like Saccharop_dh PF03435.13 EIW75881.1 - 0.027 13.4 0.1 0.04 12.9 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase IER PF05760.7 EIW75881.1 - 0.72 9.7 6.7 1.1 9.1 4.6 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) WD40 PF00400.27 EIW75883.1 - 2.4e-61 201.5 13.1 1.2e-13 50.3 0.0 6.4 6 1 0 6 6 6 6 WD domain, G-beta repeat eIF2A PF08662.6 EIW75883.1 - 3.7e-08 33.3 0.0 0.076 12.7 0.0 3.3 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIW75883.1 - 2e-06 26.2 1.6 0.46 8.5 0.0 3.5 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EIW75883.1 - 0.00016 20.0 0.3 0.16 10.2 0.1 2.7 1 1 1 3 3 3 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 EIW75883.1 - 0.00074 19.0 2.4 0.62 9.4 0.1 2.9 1 1 1 3 3 3 3 PQQ-like domain DUF3312 PF11768.3 EIW75883.1 - 0.00079 17.7 0.0 0.012 13.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) Nbas_N PF15492.1 EIW75883.1 - 0.00096 18.3 0.3 4.1 6.4 0.0 4.3 1 1 5 6 6 6 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 EIW75883.1 - 0.0019 17.7 0.6 15 5.4 0.0 4.4 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Peptidase_S9_N PF02897.10 EIW75883.1 - 0.016 13.8 0.0 0.049 12.1 0.0 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain PQQ_3 PF13570.1 EIW75883.1 - 0.018 15.3 6.9 3.3 8.1 1.2 4.2 2 1 2 4 4 4 0 PQQ-like domain Proteasome_A_N PF10584.4 EIW75883.1 - 0.045 13.0 1.0 1.1e+02 2.2 0.0 4.4 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature DPPIV_N PF00930.16 EIW75883.1 - 0.11 11.1 0.0 3.1 6.3 0.0 2.9 3 1 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region TruB_C PF09142.6 EIW75883.1 - 0.19 11.4 1.3 11 5.7 0.3 3.8 5 0 0 5 5 5 0 tRNA Pseudouridine synthase II, C terminal adh_short_C2 PF13561.1 EIW75884.1 - 1.8e-29 103.1 0.1 2.3e-29 102.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIW75884.1 - 7.3e-21 74.7 1.9 9.6e-21 74.4 1.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW75884.1 - 7.4e-11 42.0 0.4 9.5e-11 41.6 0.3 1.1 1 0 0 1 1 1 1 KR domain His_biosynth PF00977.16 EIW75884.1 - 0.00066 19.0 0.1 0.0012 18.1 0.1 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein Saccharop_dh PF03435.13 EIW75884.1 - 0.016 14.2 0.1 0.024 13.6 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Flavodoxin_4 PF12682.2 EIW75884.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Flavodoxin GST_N_3 PF13417.1 EIW75885.1 - 2e-11 43.9 0.0 4.5e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW75885.1 - 0.00028 21.0 0.0 0.0006 19.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW75885.1 - 0.00039 20.3 0.0 0.00082 19.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW75885.1 - 0.0033 17.2 0.1 0.0067 16.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW75885.1 - 0.0034 17.8 0.0 0.023 15.1 0.0 2.2 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW75885.1 - 0.0083 16.0 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RNase_H PF00075.19 EIW75886.1 - 6.5e-05 23.2 0.0 0.00012 22.4 0.0 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EIW75886.1 - 0.04 14.2 0.1 0.11 12.7 0.1 1.8 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase WD40 PF00400.27 EIW75888.1 - 5.9e-115 371.5 27.3 4.8e-12 45.2 0.1 12.1 12 0 0 12 12 12 12 WD domain, G-beta repeat eIF2A PF08662.6 EIW75888.1 - 1.7e-13 50.7 0.0 0.00041 20.1 0.0 5.2 2 2 5 7 7 7 3 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 EIW75888.1 - 2.6e-08 33.5 3.6 0.0006 19.2 0.6 3.7 3 1 0 3 3 3 2 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 EIW75888.1 - 5.9e-06 25.8 9.8 2.3 7.9 0.1 7.6 9 0 0 9 9 9 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EIW75888.1 - 1.6e-05 24.1 0.9 18 4.3 0.0 6.3 3 2 3 7 7 7 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 EIW75888.1 - 4.4e-05 21.8 7.8 1.2 7.2 0.1 6.6 2 2 3 5 5 5 2 Nucleoporin Nup120/160 DUF3312 PF11768.3 EIW75888.1 - 0.0016 16.7 0.0 0.14 10.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3312) Cytochrom_D1 PF02239.11 EIW75888.1 - 0.072 11.3 1.0 6.6 4.9 0.0 3.6 2 1 1 3 3 3 0 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 EIW75888.1 - 1.1 8.6 13.6 25 4.3 0.0 7.2 9 0 0 9 9 9 0 Proteasome subunit A N-terminal signature Pap_E4 PF02711.9 EIW75889.1 - 0.13 13.1 1.2 0.13 13.1 0.8 2.1 2 0 0 2 2 2 0 E4 protein Yip1 PF04893.12 EIW75890.1 - 0.0073 15.8 10.8 0.016 14.7 7.5 1.6 1 1 0 1 1 1 1 Yip1 domain 60KD_IMP PF02096.15 EIW75890.1 - 0.0085 15.7 1.4 0.015 15.0 1.0 1.4 1 0 0 1 1 1 1 60Kd inner membrane protein WD40 PF00400.27 EIW75893.1 - 8.7e-120 386.8 33.9 4.1e-13 48.6 0.0 13.4 13 0 0 13 13 13 13 WD domain, G-beta repeat eIF2A PF08662.6 EIW75893.1 - 3.8e-13 49.5 0.0 0.00053 19.7 0.0 5.9 1 1 8 9 9 8 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EIW75893.1 - 2e-07 30.4 0.5 9.5 6.0 0.0 7.3 8 0 0 8 8 8 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EIW75893.1 - 1.4e-06 27.6 3.3 10 5.1 0.0 8.1 1 1 8 10 10 10 2 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.4 EIW75893.1 - 0.0009 18.7 1.6 0.47 9.7 0.0 4.5 4 2 1 5 5 5 1 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.1 EIW75893.1 - 0.0015 18.0 1.9 3.8 6.9 0.0 4.0 3 1 0 3 3 3 2 PQQ-like domain ThiF PF00899.16 EIW75894.1 - 1.4e-37 128.5 0.0 2.2e-37 127.8 0.0 1.3 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EIW75894.1 - 6.7e-28 96.0 0.0 1.3e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EIW75894.1 - 1.1e-19 69.5 1.4 1.1e-19 69.5 1.0 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EIW75894.1 - 5.1e-06 26.5 0.0 0.0055 16.7 0.0 2.5 2 0 0 2 2 2 2 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 EIW75894.1 - 0.00053 20.1 0.0 0.0016 18.6 0.0 1.8 1 1 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EIW75894.1 - 0.021 14.9 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 EIW75895.1 - 2.7e-27 95.7 1.5 3.8e-27 95.2 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW75895.1 - 9.8e-16 58.2 0.0 1.6e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW75895.1 - 1.2e-12 47.8 0.3 2.1e-07 30.8 0.1 2.2 2 0 0 2 2 2 2 KR domain NAD_binding_10 PF13460.1 EIW75895.1 - 3.2e-06 27.2 0.1 9.8e-06 25.6 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EIW75895.1 - 0.0031 16.9 0.0 0.0071 15.8 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family F-box-like PF12937.2 EIW75896.1 - 7.2e-09 35.2 5.5 2.4e-08 33.5 3.8 2.0 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EIW75896.1 - 0.64 9.8 6.7 0.54 10.0 1.5 3.0 3 0 0 3 3 3 0 Leucine rich repeat adh_short_C2 PF13561.1 EIW75897.1 - 0.0019 18.0 0.0 0.0021 17.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIW75897.1 - 0.054 13.4 0.0 0.061 13.2 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase DUF1610 PF07754.6 EIW75899.1 - 0.024 14.7 0.3 0.082 13.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) zf-Mss51 PF13824.1 EIW75899.1 - 0.073 12.9 1.1 0.19 11.6 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 F-box-like PF12937.2 EIW75900.1 - 1.9e-05 24.2 6.8 2.5e-05 23.9 3.0 2.6 3 0 0 3 3 3 1 F-box-like LRR_8 PF13855.1 EIW75900.1 - 0.0003 20.4 1.3 0.0066 16.1 0.1 2.9 3 0 0 3 3 3 1 Leucine rich repeat Gemini_AC4_5_2 PF08464.5 EIW75900.1 - 0.16 11.7 0.9 0.31 10.7 0.1 1.9 2 0 0 2 2 2 0 Geminivirus AC4/5 conserved region Keratin_B2_2 PF13885.1 EIW75900.1 - 4.4 7.0 5.7 1.1 8.9 1.6 1.7 2 0 0 2 2 2 0 Keratin, high sulfur B2 protein 3-HAO PF06052.7 EIW75901.1 - 2.9e-60 202.0 0.1 3.3e-60 201.8 0.1 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EIW75901.1 - 7.2e-08 31.8 0.3 1.3e-07 31.0 0.0 1.5 2 0 0 2 2 2 1 Cupin domain AraC_binding PF02311.14 EIW75901.1 - 0.00036 20.2 0.0 0.00061 19.4 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EIW75901.1 - 0.0075 15.7 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Cupin ARD PF03079.9 EIW75901.1 - 0.091 12.7 0.1 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family Cupin_6 PF12852.2 EIW75901.1 - 0.11 12.0 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Cupin adh_short PF00106.20 EIW75902.1 - 7.3e-28 97.5 0.5 1e-27 97.0 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW75902.1 - 1.6e-13 50.9 0.0 2.4e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW75902.1 - 2.6e-10 40.2 0.1 4.1e-10 39.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW75902.1 - 5.3e-06 26.0 0.0 9.3e-06 25.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW75902.1 - 0.004 17.1 0.1 0.0057 16.6 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EIW75902.1 - 0.016 14.9 0.0 0.016 14.9 0.0 2.4 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 EIW75902.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain p450 PF00067.17 EIW75903.1 - 7.9e-64 215.8 0.0 2e-63 214.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EIW75904.1 - 5.6e-26 91.4 0.1 7.3e-26 91.0 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW75904.1 - 4.8e-13 49.4 0.0 6.7e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW75904.1 - 1e-08 35.0 0.0 1.6e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIW75904.1 - 0.011 15.6 0.1 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding 3-HAO PF06052.7 EIW75905.1 - 3.6e-61 204.9 0.0 4.1e-61 204.8 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EIW75905.1 - 2.2e-07 30.2 0.0 3.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EIW75905.1 - 0.00066 19.3 0.0 0.00099 18.8 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EIW75905.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Cupin Cupin_6 PF12852.2 EIW75905.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Cupin CDC45 PF02724.9 EIW75908.1 - 0.078 11.0 5.1 0.08 10.9 3.5 1.1 1 0 0 1 1 1 0 CDC45-like protein CVNH PF08881.5 EIW75909.1 - 3.2e-18 65.8 0.8 1.7e-17 63.4 0.6 1.8 1 1 0 1 1 1 1 CVNH domain fn1 PF00039.13 EIW75909.1 - 0.19 11.5 4.5 11 5.8 0.0 3.3 3 0 0 3 3 3 0 Fibronectin type I domain Acyl-CoA_dh_M PF02770.14 EIW75910.1 - 2.8e-06 26.7 0.0 7.2e-06 25.4 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EIW75910.1 - 0.0018 18.4 0.1 0.0038 17.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MFS_1 PF07690.11 EIW75911.1 - 1.6e-23 82.9 52.0 1.7e-19 69.7 15.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD-oxidase_C PF02913.14 EIW75912.1 - 3.4e-53 180.5 0.0 5.7e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EIW75912.1 - 2e-33 114.8 0.5 3.1e-33 114.1 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Cutinase PF01083.17 EIW75914.1 - 4.3e-31 108.0 0.4 2.5e-29 102.2 0.0 2.1 2 0 0 2 2 2 1 Cutinase Thioesterase PF00975.15 EIW75914.1 - 7.4e-05 23.0 0.0 9.9e-05 22.6 0.0 1.3 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EIW75914.1 - 0.0023 17.8 0.1 0.0038 17.1 0.1 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW75914.1 - 0.0025 17.5 0.4 0.018 14.7 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family PE-PPE PF08237.6 EIW75914.1 - 0.005 16.2 0.0 0.0074 15.7 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 EIW75914.1 - 0.0065 16.2 0.0 0.0097 15.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_9 PF10081.4 EIW75914.1 - 0.023 13.3 0.1 0.034 12.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta-hydrolase family DUF2974 PF11187.3 EIW75914.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) adh_short PF00106.20 EIW75916.1 - 7.6e-24 84.5 0.6 1.1e-23 83.9 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW75916.1 - 2.1e-22 80.0 0.0 2.6e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW75916.1 - 1.1e-09 38.2 0.1 2.4e-09 37.0 0.0 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EIW75916.1 - 4.6e-06 26.2 0.2 1.2e-05 24.8 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW75916.1 - 0.00022 21.3 0.0 0.00036 20.5 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding p450 PF00067.17 EIW75917.1 - 4.3e-64 216.7 0.0 9.6e-64 215.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 PaaX_C PF08223.6 EIW75917.1 - 0.094 12.4 0.0 6.5 6.4 0.0 2.3 2 0 0 2 2 2 0 PaaX-like protein C-terminal domain VHS PF00790.14 EIW75918.1 - 4.4e-35 120.3 0.0 1.6e-34 118.5 0.0 1.8 2 0 0 2 2 2 1 VHS domain GAT PF03127.9 EIW75918.1 - 1.5e-14 53.7 0.1 3.3e-14 52.6 0.1 1.5 1 0 0 1 1 1 1 GAT domain DUF1390 PF07150.6 EIW75920.1 - 0.13 11.6 0.5 0.23 10.7 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) zf-H2C2_5 PF13909.1 EIW75920.1 - 0.86 9.9 4.8 1.3 9.3 0.1 3.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Lipase_GDSL PF00657.17 EIW75923.1 - 3e-15 56.7 0.1 4.2e-15 56.2 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EIW75923.1 - 0.00078 19.6 4.0 0.0019 18.3 2.8 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EIW75924.1 - 1.6e-11 44.5 0.5 3.6e-11 43.3 0.4 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EIW75924.1 - 4.7e-05 23.5 1.0 0.00013 22.1 0.7 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF1286 PF06939.6 EIW75925.1 - 0.5 10.5 8.2 0.076 13.1 2.5 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1286) Abhydrolase_5 PF12695.2 EIW75926.1 - 7.2e-21 74.4 0.0 1.2e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW75926.1 - 1.7e-15 57.5 0.2 6.9e-14 52.2 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW75926.1 - 3.1e-08 33.4 0.0 5.2e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold BAAT_C PF08840.6 EIW75926.1 - 6.1e-08 32.6 0.0 1.4e-05 24.8 0.0 2.2 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 EIW75926.1 - 4.9e-05 22.8 0.2 0.011 15.1 0.0 3.0 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase AXE1 PF05448.7 EIW75926.1 - 0.0032 16.0 0.1 0.039 12.4 0.0 2.1 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EIW75926.1 - 0.0047 16.1 0.0 0.029 13.5 0.0 2.2 2 1 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 EIW75926.1 - 0.0087 15.3 0.0 0.55 9.4 0.0 2.4 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EIW75926.1 - 0.027 14.0 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 EIW75926.1 - 0.042 13.2 0.0 0.084 12.2 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Esterase PF00756.15 EIW75926.1 - 0.085 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase FSH1 PF03959.8 EIW75926.1 - 0.11 11.9 0.0 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Baculo_PEP_C PF04513.7 EIW75927.1 - 7e-05 22.6 14.2 0.17 11.7 2.2 4.2 1 1 1 3 3 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2789 PF10982.3 EIW75927.1 - 0.00031 20.6 0.1 8.4 6.4 0.0 4.4 3 1 1 4 4 4 1 Protein of unknown function (DUF2789) YqeY PF09424.5 EIW75927.1 - 0.0011 18.7 0.4 9.1 6.1 0.0 4.1 1 1 3 4 4 4 1 Yqey-like protein DUF2746 PF10874.3 EIW75927.1 - 0.0016 18.6 0.0 9.3 6.5 0.0 4.5 5 1 0 5 5 5 0 Protein of unknown function (DUF2746) DUF2175 PF09943.4 EIW75927.1 - 0.0039 17.2 0.1 33 4.5 0.0 4.0 3 1 1 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2175) Spidroin_MaSp PF11260.3 EIW75927.1 - 0.0068 16.4 10.3 3.9 7.6 0.0 4.6 3 2 2 5 5 4 1 Major ampullate spidroin 1 and 2 DUF2580 PF10824.3 EIW75927.1 - 0.0079 16.5 5.8 0.47 10.8 0.1 4.4 5 1 1 6 6 5 1 Protein of unknown function (DUF2580) HCV_NS4b PF01001.14 EIW75927.1 - 0.013 14.9 0.0 2.9 7.2 0.0 3.1 2 1 1 3 3 3 0 Hepatitis C virus non-structural protein NS4b PerC PF06069.6 EIW75927.1 - 0.016 15.1 0.0 55 3.8 0.0 4.9 5 1 1 6 6 6 0 PerC transcriptional activator DUF948 PF06103.6 EIW75927.1 - 0.024 14.4 11.1 15 5.5 0.3 6.9 2 2 3 6 6 6 0 Bacterial protein of unknown function (DUF948) PG_binding_2 PF08823.6 EIW75927.1 - 0.043 13.9 1.1 0.84 9.7 0.0 3.5 4 2 0 4 4 4 0 Putative peptidoglycan binding domain Gp_dh_C PF02800.15 EIW75927.1 - 0.043 13.2 3.0 2.6 7.4 0.1 4.0 2 2 0 4 4 4 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Erp_C PF06780.6 EIW75927.1 - 0.068 13.0 0.1 0.84 9.4 0.0 2.7 2 1 1 3 3 3 0 Erp protein C-terminus WXG100 PF06013.7 EIW75927.1 - 0.34 10.9 1.7 44 4.1 0.0 4.6 5 1 0 5 5 4 0 Proteins of 100 residues with WXG HsbA PF12296.3 EIW75927.1 - 0.42 10.4 11.4 1.9 8.3 0.5 3.6 1 1 0 3 3 3 0 Hydrophobic surface binding protein A Qn_am_d_aIII PF09099.5 EIW75927.1 - 4 7.8 14.4 0.9 9.8 0.2 4.9 4 1 2 6 6 6 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III zf-UBR PF02207.15 EIW75928.1 - 3.8e-08 32.9 7.3 3.8e-08 32.9 5.1 2.8 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 EIW75928.1 - 1.2e-06 28.1 1.1 1.2e-06 28.1 0.8 3.4 4 0 0 4 4 4 1 PHD-finger HrpF PF06266.7 EIW75928.1 - 0.32 11.1 3.7 3.7 7.7 0.0 2.5 2 0 0 2 2 2 0 HrpF protein Bunya_G2 PF03563.8 EIW75930.1 - 0.18 10.6 2.7 0.37 9.6 1.9 1.5 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 Baculo_PEP_C PF04513.7 EIW75931.1 - 1.2e-06 28.3 0.1 0.37 10.6 0.0 3.8 1 1 2 3 3 3 3 Baculovirus polyhedron envelope protein, PEP, C terminus Cactin_mid PF10312.4 EIW75931.1 - 1.9e-06 27.2 3.8 3.6 6.8 0.1 5.2 1 1 4 5 5 5 4 Conserved mid region of cactin Phage_fiber_C PF06820.7 EIW75931.1 - 0.00053 20.0 6.6 7.5 6.7 0.1 5.2 4 1 2 6 6 6 1 Putative prophage tail fibre C-terminus Phasin PF05597.6 EIW75931.1 - 0.001 18.8 8.0 3.1 7.5 0.2 4.7 1 1 3 4 4 4 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Apolipoprotein PF01442.13 EIW75931.1 - 0.0092 15.5 12.1 0.33 10.4 5.7 3.2 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain Cep57_MT_bd PF06657.8 EIW75931.1 - 0.02 14.7 3.6 35 4.4 0.1 4.7 1 1 3 4 4 4 0 Centrosome microtubule-binding domain of Cep57 HTH_13 PF11972.3 EIW75931.1 - 0.14 12.0 19.6 16 5.4 0.1 8.5 2 2 9 12 12 12 0 HTH DNA binding domain DUF1079 PF06435.6 EIW75931.1 - 0.27 11.1 1.1 3.2e+02 1.4 0.0 4.2 4 0 0 4 4 4 0 Repeat of unknown function (DUF1079) Cortex-I_coil PF09304.5 EIW75931.1 - 3.2 7.8 13.2 7.1 6.7 0.2 4.5 1 1 4 5 5 5 0 Cortexillin I, coiled coil NAD_binding_2 PF03446.10 EIW75933.1 - 8.6e-21 74.4 0.1 2.4e-20 73.0 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EIW75933.1 - 1.1e-09 38.3 0.2 2.4e-09 37.2 0.1 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EIW75933.1 - 2.3e-06 27.9 0.0 4.7e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EIW75933.1 - 8.6e-06 25.8 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.10 EIW75933.1 - 0.00012 20.9 0.0 0.0002 20.2 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family 2-Hacid_dh_C PF02826.14 EIW75933.1 - 0.0041 16.2 0.0 0.0085 15.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 EIW75933.1 - 0.0053 17.1 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EIW75933.1 - 0.12 12.9 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold S4 PF01479.20 EIW75934.1 - 4.4e-11 42.0 0.0 7.7e-11 41.2 0.0 1.4 1 0 0 1 1 1 1 S4 domain S4_2 PF13275.1 EIW75934.1 - 0.006 16.1 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 S4 domain Pol_alpha_B_N PF08418.5 EIW75934.1 - 1.6 8.2 4.9 2.6 7.5 3.4 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Ferric_reduct PF01794.14 EIW75935.1 - 2.4e-16 59.9 6.9 2.4e-16 59.9 4.8 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EIW75935.1 - 3.2e-11 43.0 0.0 6.9e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EIW75935.1 - 3.8e-08 33.4 0.0 1.7e-05 24.7 0.0 2.2 1 1 1 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EIW75936.1 - 6e-17 61.8 7.0 6e-17 61.8 4.8 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EIW75936.1 - 4.8e-13 48.8 0.0 8.4e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EIW75936.1 - 2.5e-06 27.4 0.0 4.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain GH3 PF03321.8 EIW75937.1 - 7.2e-37 127.0 0.0 9.1e-37 126.7 0.0 1.0 1 0 0 1 1 1 1 GH3 auxin-responsive promoter zf-RVT PF13966.1 EIW75938.1 - 0.0048 17.1 0.2 0.0066 16.7 0.2 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF3307 PF11750.3 EIW75939.1 - 0.036 13.7 0.4 0.081 12.6 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3307) Methyltransf_11 PF08241.7 EIW75940.1 - 1.2e-12 48.1 0.0 3.4e-12 46.6 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW75940.1 - 2.9e-09 37.5 0.0 5.7e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW75940.1 - 3.7e-08 33.7 0.0 6.7e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW75940.1 - 4.8e-08 32.8 0.0 8.1e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW75940.1 - 7.7e-07 29.1 0.1 1.9e-06 27.8 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW75940.1 - 1.4e-06 27.9 0.0 5.4e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW75940.1 - 8.4e-05 22.8 0.0 0.00015 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW75940.1 - 0.0048 16.0 0.0 0.0065 15.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.1 EIW75940.1 - 0.01 16.6 0.1 0.022 15.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EIW75940.1 - 0.035 13.1 0.0 0.061 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_28 PF02636.12 EIW75940.1 - 0.065 12.6 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.14 EIW75940.1 - 0.097 12.1 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) HMG_box PF00505.14 EIW75941.1 - 5.6e-17 61.7 7.9 2.2e-08 34.2 0.1 3.3 2 1 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.5 EIW75941.1 - 1.3e-13 51.1 2.3 3.7e-09 36.8 0.2 2.6 2 0 0 2 2 2 2 HMG-box domain DUF3504 PF12012.3 EIW75941.1 - 0.0046 16.7 1.1 0.0075 16.0 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3504) YABBY PF04690.8 EIW75941.1 - 0.032 14.4 1.5 0.05 13.8 1.1 1.3 1 0 0 1 1 1 0 YABBY protein Med13_C PF06333.7 EIW75941.1 - 0.081 11.4 0.4 0.12 10.9 0.2 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal Med8 PF10232.4 EIW75942.1 - 4e-05 23.2 1.1 9.3e-05 22.0 0.7 1.7 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 Herpes_glycop_H PF02489.11 EIW75942.1 - 0.12 10.3 0.0 0.14 10.1 0.0 1.0 1 0 0 1 1 1 0 Herpesvirus glycoprotein H Methyltransf_11 PF08241.7 EIW75943.1 - 2.3e-12 47.2 0.0 1.1e-11 45.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW75943.1 - 3.5e-10 39.8 0.0 4.9e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW75943.1 - 8.9e-10 39.1 0.0 1.6e-09 38.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW75943.1 - 3e-07 30.4 0.3 5.2e-07 29.7 0.2 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW75943.1 - 3.1e-07 30.8 0.0 6.8e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW75943.1 - 4.6e-06 26.3 0.0 0.002 17.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EIW75943.1 - 0.0012 19.2 0.0 0.003 17.8 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain RrnaAD PF00398.15 EIW75943.1 - 0.0012 17.9 0.0 0.0019 17.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ubie_methyltran PF01209.13 EIW75943.1 - 0.0054 15.8 0.0 0.012 14.7 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EIW75943.1 - 0.069 13.1 0.0 0.43 10.5 0.0 2.0 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_24 PF13578.1 EIW75943.1 - 0.086 13.6 0.0 0.18 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EIW75943.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase MFS_1 PF07690.11 EIW75944.1 - 1.1e-35 123.0 29.4 1.1e-35 123.0 20.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EIW75945.1 - 2.8e-39 134.8 28.0 3.5e-39 134.5 19.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1119 PF06550.6 EIW75945.1 - 1 8.4 9.5 0.025 13.7 1.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1119) Pkinase PF00069.20 EIW75946.1 - 2.1e-37 128.6 0.0 3.3e-37 128.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW75946.1 - 8.2e-32 110.2 0.0 1.1e-31 109.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW75946.1 - 7.6e-05 21.8 0.0 0.00014 20.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Rib_5-P_isom_A PF06026.9 EIW75947.1 - 7.4e-55 184.9 0.0 1.6e-54 183.7 0.0 1.5 2 0 0 2 2 2 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Helicase_C PF00271.26 EIW75948.1 - 3.9e-19 68.2 0.0 5.5e-18 64.5 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIW75948.1 - 2.8e-14 52.9 0.0 6.2e-14 51.8 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Tbf5 PF06331.7 EIW75948.1 - 0.0003 20.5 0.2 0.00063 19.4 0.2 1.5 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 T4SS-DNA_transf PF02534.9 EIW75948.1 - 0.0085 14.7 0.0 0.025 13.1 0.0 1.7 2 0 0 2 2 2 1 Type IV secretory system Conjugative DNA transfer ResIII PF04851.10 EIW75948.1 - 0.084 12.6 0.0 0.25 11.1 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit p450 PF00067.17 EIW75950.1 - 3.7e-65 220.2 0.0 4.8e-65 219.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SAE2 PF08573.5 EIW75951.1 - 3.8e-15 56.3 6.3 3.8e-15 56.3 4.4 3.9 2 2 0 2 2 2 1 DNA repair protein endonuclease SAE2/CtIP C-terminus WEMBL PF05701.6 EIW75951.1 - 0.29 9.5 11.5 0.0067 14.9 3.0 1.9 2 0 0 2 2 2 0 Weak chloroplast movement under blue light EPSP_synthase PF00275.15 EIW75953.1 - 2.2e-113 378.8 0.0 3.9e-113 378.0 0.0 1.3 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EIW75953.1 - 2.1e-94 315.2 0.0 3.7e-94 314.5 0.0 1.4 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EIW75953.1 - 6.3e-63 212.4 0.0 9.1e-63 211.9 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EIW75953.1 - 9.5e-30 103.5 0.0 8.9e-29 100.3 0.0 2.2 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EIW75953.1 - 1.8e-23 82.3 0.0 4.8e-23 81.0 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EIW75953.1 - 1.4e-14 54.3 0.0 4e-14 52.8 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Fe-ADH_2 PF13685.1 EIW75953.1 - 1.1e-07 31.3 0.0 2.8e-07 30.0 0.0 1.7 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Saccharop_dh PF03435.13 EIW75953.1 - 0.00029 19.9 0.7 0.019 13.9 0.0 2.8 3 0 0 3 3 3 1 Saccharopine dehydrogenase AAA_17 PF13207.1 EIW75953.1 - 0.003 18.3 0.1 0.013 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIW75953.1 - 0.053 13.5 0.0 0.25 11.3 0.0 2.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 EIW75953.1 - 0.11 12.4 0.0 0.36 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Pyr_redox_2 PF07992.9 EIW75954.1 - 5e-26 91.8 0.0 7.2e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW75954.1 - 2.5e-11 43.8 0.1 8.7e-10 38.8 0.0 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW75954.1 - 0.00049 20.2 0.0 0.58 10.1 0.0 3.5 3 1 1 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EIW75954.1 - 0.079 13.2 1.9 0.46 10.7 0.0 2.8 4 0 0 4 4 4 0 Putative NAD(P)-binding SPC25 PF06703.6 EIW75955.1 - 0.18 11.3 0.6 0.27 10.8 0.4 1.3 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) DUF751 PF05421.6 EIW75955.1 - 4.2 7.7 7.4 0.99 9.7 0.9 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF751) GFA PF04828.9 EIW75956.1 - 5.4e-23 80.7 0.1 7.6e-23 80.2 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DNA_ligase_ZBD PF03119.11 EIW75956.1 - 0.034 13.8 0.1 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain NOB1_Zn_bind PF08772.6 EIW75956.1 - 0.21 11.4 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Cys_rich_CWC PF14375.1 EIW75956.1 - 0.21 11.5 5.6 0.25 11.3 1.3 2.1 2 0 0 2 2 2 0 Cysteine-rich CWC GFA PF04828.9 EIW75958.1 - 2.3e-23 81.9 0.6 3.3e-23 81.4 0.4 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Cys_rich_CWC PF14375.1 EIW75958.1 - 0.023 14.6 3.1 0.023 14.6 2.1 1.7 2 0 0 2 2 2 0 Cysteine-rich CWC WH1 PF00568.18 EIW75960.1 - 2.1e-21 75.7 0.0 3e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 WH1 domain PBD PF00786.23 EIW75960.1 - 3.7e-10 40.0 0.0 8.9e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.15 EIW75960.1 - 0.0063 16.0 0.0 0.017 14.7 0.0 1.8 1 0 0 1 1 1 1 WH2 motif RAP1 PF07218.6 EIW75960.1 - 0.081 11.0 1.7 0.11 10.5 1.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Cation_ATPase_N PF00690.21 EIW75960.1 - 0.19 11.2 0.0 0.68 9.4 0.0 2.0 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus EF-hand_1 PF00036.27 EIW75961.1 - 5.9e-43 140.9 12.6 2.6e-10 38.8 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EIW75961.1 - 1.5e-38 130.7 3.7 2.6e-21 75.5 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EIW75961.1 - 1.4e-34 117.4 11.1 1.2e-16 60.0 0.4 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EIW75961.1 - 1.1e-31 105.8 7.0 1.2e-09 37.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EIW75961.1 - 2.5e-28 96.1 7.3 8.3e-07 28.0 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EIW75961.1 - 2.6e-15 56.0 0.2 2.2e-08 33.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EIW75961.1 - 2.4e-10 40.0 0.7 6.6e-05 22.5 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EIW75961.1 - 3.9e-09 36.5 0.0 0.0004 20.3 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EIW75961.1 - 2e-07 30.5 0.1 0.11 12.0 0.0 3.8 3 1 1 4 4 4 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EIW75961.1 - 1.8e-06 27.7 1.4 2.5e-05 24.1 0.1 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand EF-hand_like PF09279.6 EIW75961.1 - 0.00021 21.2 0.4 0.0036 17.2 0.0 2.4 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like DUF1103 PF06513.6 EIW75961.1 - 0.00027 20.4 1.2 0.00031 20.2 0.8 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) Caleosin PF05042.8 EIW75961.1 - 0.00029 20.4 0.1 0.037 13.6 0.0 2.4 1 1 0 2 2 2 1 Caleosin related protein TerB PF05099.8 EIW75961.1 - 0.0032 17.2 0.1 0.27 10.9 0.0 2.2 1 1 1 2 2 2 1 Tellurite resistance protein TerB MotA_activ PF09114.5 EIW75961.1 - 0.014 15.1 0.1 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Poly_export PF02563.11 EIW75961.1 - 0.018 14.7 0.1 3.9 7.3 0.0 3.1 1 1 2 3 3 3 0 Polysaccharide biosynthesis/export protein RNA_pol_Rpb4 PF03874.11 EIW75961.1 - 0.034 14.1 1.2 6.2 6.8 0.1 2.6 3 0 0 3 3 2 0 RNA polymerase Rpb4 Tenui_NCP PF04876.7 EIW75961.1 - 0.042 13.4 0.1 0.81 9.2 0.0 2.1 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein Toprim_2 PF13155.1 EIW75961.1 - 0.067 13.5 0.6 13 6.2 0.0 2.4 1 1 1 2 2 2 0 Toprim-like LNS2 PF08235.8 EIW75961.1 - 0.084 12.4 0.1 0.48 9.9 0.0 1.9 2 0 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) 3-PAP PF12578.3 EIW75963.1 - 1.1 9.1 4.3 1.2 8.9 3.0 1.1 1 0 0 1 1 1 0 Myotubularin-associated protein RAP1 PF07218.6 EIW75963.1 - 9 4.2 7.9 10 4.1 5.5 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) p450 PF00067.17 EIW75964.1 - 3.5e-69 233.5 0.0 4.2e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2373 PF10180.4 EIW75965.1 - 0.035 13.6 0.1 0.13 11.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) DUF1667 PF07892.6 EIW75965.1 - 0.042 13.5 0.0 0.076 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1667) Borrelia_P83 PF05262.6 EIW75968.1 - 0.0012 17.1 3.4 0.0016 16.7 2.3 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein Peptidase_C54 PF03416.14 EIW75969.1 - 9.4e-86 287.4 0.0 7.4e-85 284.4 0.0 2.0 1 1 0 1 1 1 1 Peptidase family C54 ABM PF03992.11 EIW75971.1 - 0.0011 18.9 0.2 0.003 17.5 0.0 1.8 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase Mit_proteolip PF08039.6 EIW75972.1 - 0.12 12.3 0.4 0.32 10.9 0.3 1.7 1 0 0 1 1 1 0 Mitochondrial proteolipid DUF2304 PF10066.4 EIW75972.1 - 0.68 9.7 5.1 1.1 9.0 3.1 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Aldedh PF00171.17 EIW75974.1 - 3.4e-185 615.7 1.3 3.9e-185 615.6 0.9 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIW75974.1 - 0.0016 17.2 0.0 0.016 13.9 0.0 2.1 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) zf-H2C2_2 PF13465.1 EIW75975.1 - 2.9e-09 36.7 8.3 2e-07 30.9 0.3 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EIW75975.1 - 8.4e-07 28.9 7.0 0.011 16.0 0.2 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 EIW75975.1 - 7.2e-06 25.9 5.8 0.00054 20.0 1.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc-finger domain zf-C2H2_4 PF13894.1 EIW75975.1 - 0.00032 20.8 8.0 0.059 13.7 1.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EIW75975.1 - 0.072 13.2 5.1 0.52 10.4 3.3 2.0 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EIW75975.1 - 0.13 12.2 3.5 0.39 10.7 0.0 2.8 3 0 0 3 3 3 0 C2H2-type zinc finger ECH PF00378.15 EIW75976.1 - 1.2e-41 142.4 0.1 1.7e-41 141.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EIW75976.1 - 1.1e-05 25.4 0.1 3.3e-05 24.0 0.1 1.6 2 1 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region Ribosomal_L18e PF00828.14 EIW75976.1 - 0.06 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L18e/L15 F-box-like PF12937.2 EIW75978.1 - 0.00015 21.4 0.0 0.00035 20.2 0.0 1.7 1 0 0 1 1 1 1 F-box-like Protoglobin PF11563.3 EIW75978.1 - 0.029 14.0 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Protoglobin CitMHS PF03600.11 EIW75979.1 - 9.9e-10 37.5 15.6 9.9e-10 37.5 10.8 2.4 2 0 0 2 2 2 2 Citrate transporter CorA PF01544.13 EIW75980.1 - 2.7e-23 82.4 20.3 4.3e-12 45.6 3.4 3.3 2 2 0 2 2 2 2 CorA-like Mg2+ transporter protein Glyco_hydro_76 PF03663.9 EIW75981.1 - 4.8e-20 72.2 21.5 5.3e-16 58.9 3.7 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 76 DIOX_N PF14226.1 EIW75982.1 - 1.9e-15 57.3 0.0 3.4e-15 56.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIW75982.1 - 2.4e-09 37.3 0.0 5.6e-09 36.2 0.0 1.6 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily RFPL3_antisense PF10489.4 EIW75982.1 - 0.00043 20.0 0.0 0.00085 19.1 0.0 1.4 1 0 0 1 1 1 1 Ret finger protein-like 3 antisense DUF2422 PF10337.4 EIW75984.1 - 2.4e-62 211.2 7.2 1.2e-53 182.5 0.9 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EIW75984.1 - 2.7e-52 177.6 0.1 6e-52 176.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2421) FUSC_2 PF13515.1 EIW75984.1 - 4.8e-10 39.4 14.9 4.8e-10 39.4 10.3 3.8 4 0 0 4 4 4 1 Fusaric acid resistance protein-like UPF0139 PF03669.8 EIW75984.1 - 0.16 11.5 0.3 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0139) ALMT PF11744.3 EIW75984.1 - 3.9 6.0 9.2 12 4.4 6.4 1.8 1 0 0 1 1 1 0 Aluminium activated malate transporter UPF0016 PF01169.14 EIW75985.1 - 1.6e-44 149.8 17.2 1.4e-22 79.5 2.9 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 LSM PF01423.17 EIW75986.1 - 1.7e-16 59.4 0.2 2e-16 59.2 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EIW75986.1 - 2.8e-06 27.1 0.1 3.5e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Ras PF00071.17 EIW75987.1 - 1.5e-36 125.2 0.0 1.6e-36 125.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW75987.1 - 1.8e-17 63.9 0.0 2.4e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW75987.1 - 1.8e-07 30.5 0.0 2.2e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW75987.1 - 4.6e-06 25.9 0.0 7.5e-06 25.2 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EIW75987.1 - 0.00045 20.3 0.0 0.00053 20.1 0.0 1.2 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EIW75987.1 - 0.00055 19.8 0.0 0.00063 19.6 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIW75987.1 - 0.0023 17.3 0.0 0.024 14.0 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 EIW75987.1 - 0.0029 17.2 0.3 0.013 15.1 0.1 1.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EIW75987.1 - 0.038 13.1 0.2 0.044 12.9 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EIW75987.1 - 0.13 12.2 0.6 0.19 11.6 0.3 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 EIW75987.1 - 0.14 11.6 0.3 0.28 10.5 0.2 1.4 1 1 0 1 1 1 0 AAA-like domain MobB PF03205.9 EIW75987.1 - 0.16 11.6 0.1 0.25 11.0 0.1 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF4396 PF14342.1 EIW75988.1 - 3.7 7.6 13.0 0.18 11.9 3.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4396) ARID PF01388.16 EIW75989.1 - 1.6e-07 31.0 0.1 6e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain p450 PF00067.17 EIW75990.1 - 1.6e-68 231.3 0.0 2.9e-68 230.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 EIW75991.1 - 4.6e-29 101.3 0.0 5.7e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW75991.1 - 1.1e-26 93.5 0.0 1.3e-26 93.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW75991.1 - 8.9e-06 24.8 0.0 1.1e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like p450 PF00067.17 EIW75992.1 - 8.4e-70 235.5 0.0 1.6e-69 234.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 EIW75993.1 - 9.4e-32 110.1 0.0 2e-31 109.0 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase RPA_C PF08784.6 EIW75993.1 - 0.0038 17.5 0.0 0.013 15.8 0.0 1.9 1 1 0 1 1 1 1 Replication protein A C terminal GidB PF02527.10 EIW75993.1 - 0.0076 15.4 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.9 EIW75993.1 - 0.013 14.9 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DUF2373 PF10180.4 EIW75994.1 - 0.0053 16.2 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) CPL PF08144.6 EIW75996.1 - 1.4e-20 73.6 0.0 3.1e-19 69.2 0.0 3.1 3 0 0 3 3 3 1 CPL (NUC119) domain adh_short PF00106.20 EIW75997.1 - 1.1e-28 100.1 0.0 1.5e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW75997.1 - 2.3e-16 60.2 0.0 3.2e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW75997.1 - 1.4e-12 47.6 0.0 2.4e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIW75997.1 - 8.7e-06 25.8 0.0 1.8e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW75997.1 - 9.6e-06 25.1 0.0 2.3e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIW75997.1 - 0.013 14.3 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 EIW75997.1 - 0.06 13.1 0.0 0.16 11.7 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ThiF PF00899.16 EIW75998.1 - 0.00017 21.3 0.0 0.00037 20.3 0.0 1.6 1 0 0 1 1 1 1 ThiF family DUF21 PF01595.15 EIW75999.1 - 1.5e-31 109.1 3.4 2.6e-31 108.3 2.3 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EIW75999.1 - 1.6e-06 27.7 0.3 0.018 14.8 0.0 3.5 3 0 0 3 3 3 3 CBS domain GMC_oxred_N PF00732.14 EIW76000.1 - 2e-58 197.9 0.0 2.8e-58 197.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIW76000.1 - 8.3e-31 107.2 0.0 1.6e-30 106.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIW76000.1 - 0.0013 17.7 2.0 0.0081 15.0 1.4 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIW76000.1 - 0.0024 17.9 0.1 1.9 8.5 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW76000.1 - 0.015 15.1 0.0 0.68 9.7 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW76000.1 - 0.021 14.8 1.5 0.039 13.9 0.3 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIW76000.1 - 0.089 11.6 0.1 0.14 11.0 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Methyltransf_2 PF00891.13 EIW76001.1 - 4.1e-29 101.4 0.0 9.5e-29 100.2 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EIW76001.1 - 5.2e-08 32.7 0.0 8.9e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW76001.1 - 8.6e-06 25.4 0.0 1.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW76001.1 - 1.5e-05 25.4 0.0 4.7e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW76001.1 - 2.4e-05 24.8 0.0 9.7e-05 22.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW76001.1 - 0.00024 21.5 0.0 0.00074 19.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW76001.1 - 0.012 15.0 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.4 EIW76001.1 - 0.031 13.7 0.0 0.065 12.6 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Ribosomal_L30 PF00327.15 EIW76002.1 - 3.4e-11 42.5 0.1 4.6e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Abhydrolase_6 PF12697.2 EIW76003.1 - 2e-22 80.2 1.0 2.6e-22 79.8 0.7 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW76003.1 - 6.2e-07 29.2 0.0 1.2e-06 28.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW76003.1 - 8e-06 25.5 0.0 0.00011 21.9 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EIW76003.1 - 4.7e-05 23.1 0.0 8.6e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 EIW76003.1 - 0.0073 16.5 0.0 0.01 16.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF2305 PF10230.4 EIW76003.1 - 0.051 12.9 0.0 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 EIW76003.1 - 0.051 13.1 0.0 0.079 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Thiolase_C PF02803.13 EIW76003.1 - 0.082 12.3 0.0 2.5 7.5 0.0 2.2 2 0 0 2 2 2 0 Thiolase, C-terminal domain DUF221 PF02714.10 EIW76004.1 - 4e-100 334.8 22.5 7.4e-100 333.9 15.6 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EIW76004.1 - 5.5e-37 126.7 2.3 5.5e-37 126.7 1.6 2.2 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EIW76004.1 - 7.2e-12 45.6 0.0 2.6e-11 43.8 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) LysM PF01476.15 EIW76007.1 - 1.3e-10 40.9 0.6 0.00033 20.4 0.0 2.3 2 0 0 2 2 2 2 LysM domain EF-hand_7 PF13499.1 EIW76009.1 - 2.8e-13 49.8 0.0 7.4e-09 35.6 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EIW76009.1 - 3.1e-11 42.1 0.3 4.1e-05 23.1 0.1 3.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 EIW76009.1 - 6.6e-11 40.7 0.3 0.00034 19.7 0.0 3.7 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 EIW76009.1 - 1.1e-07 31.3 0.0 8.3e-06 25.3 0.0 3.3 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.1 EIW76009.1 - 1.9e-05 24.4 0.0 0.039 13.8 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain UPF0154 PF03672.8 EIW76009.1 - 0.003 17.1 0.0 0.15 11.7 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0154) EF-hand_5 PF13202.1 EIW76009.1 - 0.0033 16.6 0.2 1.2 8.6 0.0 2.7 2 0 0 2 2 2 2 EF hand EFhand_Ca_insen PF08726.5 EIW76009.1 - 0.019 14.9 0.0 0.35 10.8 0.0 2.4 2 1 0 2 2 2 0 Ca2+ insensitive EF hand UBX PF00789.15 EIW76010.1 - 2e-08 34.1 0.0 4.6e-07 29.8 0.0 2.4 2 0 0 2 2 2 1 UBX domain HSP70 PF00012.15 EIW76010.1 - 1.6 6.5 3.8 2.2 6.0 2.6 1.1 1 0 0 1 1 1 0 Hsp70 protein Lar_restr_allev PF14354.1 EIW76012.1 - 0.13 12.5 0.4 0.16 12.2 0.2 1.2 1 0 0 1 1 1 0 Restriction alleviation protein Lar RNase_H PF00075.19 EIW76014.1 - 4.8e-07 30.1 0.0 7.7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 RNase H Exo_endo_phos_2 PF14529.1 EIW76015.1 - 1.7e-09 37.2 0.8 6e-09 35.5 0.1 2.2 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase CTP_transf_3 PF02348.14 EIW76015.1 - 0.027 14.1 0.8 0.13 11.8 0.0 2.2 1 1 1 2 2 2 0 Cytidylyltransferase Flexi_CP PF00286.15 EIW76018.1 - 0.019 14.6 1.4 0.029 14.0 0.1 1.9 1 1 0 2 2 2 0 Viral coat protein UBN2_2 PF14227.1 EIW76019.1 - 0.045 13.3 0.0 0.089 12.3 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Nop14 PF04147.7 EIW76024.1 - 0.019 12.9 2.7 0.019 12.9 1.9 1.0 1 0 0 1 1 1 0 Nop14-like family DUF1840 PF08895.6 EIW76024.1 - 0.042 13.8 2.0 0.062 13.3 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) TRAP_alpha PF03896.11 EIW76024.1 - 0.88 8.5 3.5 1.1 8.2 2.4 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit HALZ PF02183.13 EIW76027.1 - 0.13 12.0 1.7 0.43 10.3 1.1 1.9 1 1 1 2 2 2 0 Homeobox associated leucine zipper RNase_H PF00075.19 EIW76032.1 - 0.0077 16.5 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 RNase H Streptin-Immun PF11083.3 EIW76037.1 - 0.058 13.3 1.0 1.9 8.5 0.0 2.7 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein SIMPL PF04402.9 EIW76037.1 - 0.19 11.5 0.8 0.33 10.7 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF541) C5-epim_C PF06662.8 EIW76040.1 - 0.043 13.1 0.0 0.044 13.0 0.0 1.0 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus DUF930 PF06059.7 EIW76041.1 - 0.012 15.8 0.0 0.018 15.2 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF930) DUF2478 PF10649.4 EIW76043.1 - 0.028 13.7 1.0 0.09 12.1 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2478) UBN2_3 PF14244.1 EIW76044.1 - 3.4e-07 29.9 0.1 6.2e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIW76044.1 - 0.1 12.3 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type PAT1 PF09770.4 EIW76044.1 - 0.24 9.6 28.4 0.33 9.1 19.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EIW76044.1 - 0.61 9.4 25.1 1.1 8.6 17.4 1.4 1 0 0 1 1 1 0 Vta1 like Saccharop_dh PF03435.13 EIW76045.1 - 1.5e-51 175.6 0.0 2.5e-51 174.8 0.0 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EIW76045.1 - 3.8e-08 33.5 0.1 6.7e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 EIW76045.1 - 0.00071 19.8 0.1 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EIW76045.1 - 0.0033 17.4 0.1 0.0069 16.4 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding IlvN PF07991.7 EIW76045.1 - 0.0047 16.2 0.0 0.0077 15.6 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_7 PF13241.1 EIW76045.1 - 0.0051 17.0 0.1 0.015 15.5 0.1 1.7 2 0 0 2 2 2 1 Putative NAD(P)-binding DapB_N PF01113.15 EIW76045.1 - 0.015 15.2 0.1 0.015 15.2 0.1 1.6 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 EIW76045.1 - 0.025 13.7 0.0 0.054 12.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 EIW76045.1 - 0.039 14.3 0.1 0.066 13.6 0.1 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain TFIIA PF03153.8 EIW76047.1 - 3 7.6 8.2 4.3 7.1 5.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CMAS PF02353.15 EIW76048.1 - 2.3e-68 230.2 0.1 2.9e-68 229.9 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EIW76048.1 - 3.4e-14 52.8 0.1 2.3e-13 50.1 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW76048.1 - 1.5e-09 38.2 0.0 8.9e-09 35.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW76048.1 - 2.2e-06 28.2 0.0 6.5e-06 26.7 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW76048.1 - 2.8e-05 24.4 0.0 6.2e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW76048.1 - 7.4e-05 22.7 0.0 0.00038 20.4 0.0 2.1 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW76048.1 - 0.00012 22.3 0.0 0.00034 20.9 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW76048.1 - 0.00053 19.6 0.0 0.001 18.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW76048.1 - 0.00083 18.7 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.8 EIW76048.1 - 0.0016 17.7 0.0 0.0032 16.8 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 PCMT PF01135.14 EIW76048.1 - 0.053 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 EIW76048.1 - 0.1 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 EIW76048.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_L37 PF08561.5 EIW76049.1 - 8.9e-18 63.6 2.8 3.8e-17 61.6 1.9 1.9 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 DUF1589 PF07628.6 EIW76049.1 - 0.031 14.2 0.0 0.039 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1589) YIF1 PF03878.10 EIW76050.1 - 1.1e-79 266.9 3.8 1.4e-79 266.5 2.6 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EIW76050.1 - 4.9e-07 29.3 5.1 7.8e-07 28.7 3.5 1.2 1 0 0 1 1 1 1 Yip1 domain AvrRpt-cleavage PF05627.6 EIW76050.1 - 0.087 11.8 0.1 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Cleavage site for pathogenic type III effector avirulence factor Avr MCLC PF05934.6 EIW76050.1 - 0.17 10.1 0.1 0.25 9.5 0.1 1.1 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF3985 PF13153.1 EIW76050.1 - 7.5 6.4 13.1 1.4 8.7 0.4 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3985) p450 PF00067.17 EIW76051.1 - 8.8e-71 238.7 0.0 9.9e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Nrap PF03813.9 EIW76052.1 - 8.8e-204 678.9 0.0 1.1e-203 678.5 0.0 1.0 1 0 0 1 1 1 1 Nrap protein Nop14 PF04147.7 EIW76052.1 - 0.65 7.8 6.8 1 7.1 4.7 1.2 1 0 0 1 1 1 0 Nop14-like family UQ_con PF00179.21 EIW76054.1 - 8.2e-40 135.4 0.0 1.1e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIW76054.1 - 0.17 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B ParA PF10609.4 EIW76055.1 - 3.4e-29 100.5 0.1 5.5e-29 99.8 0.0 1.3 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EIW76055.1 - 1.1e-15 57.6 0.0 2.9e-07 30.1 0.2 2.3 2 1 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EIW76055.1 - 2.7e-06 27.3 0.1 1.4e-05 25.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 EIW76055.1 - 0.00092 18.3 0.1 0.005 15.9 0.1 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 EIW76055.1 - 0.0015 17.9 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain MipZ PF09140.6 EIW76055.1 - 0.018 14.0 0.1 0.034 13.2 0.0 1.4 1 0 0 1 1 1 0 ATPase MipZ Fer4_NifH PF00142.13 EIW76055.1 - 0.08 12.1 0.1 0.12 11.4 0.1 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family rRNA_proc-arch PF13234.1 EIW76056.1 - 3.6e-97 324.7 0.0 5.4e-97 324.1 0.0 1.3 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 EIW76056.1 - 1.3e-58 197.2 0.3 2.8e-58 196.1 0.2 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EIW76056.1 - 1.4e-21 76.7 0.0 3.1e-21 75.6 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW76056.1 - 1e-06 28.4 0.0 2.5e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain T2SE PF00437.15 EIW76056.1 - 0.0056 15.6 0.0 0.012 14.5 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.11 EIW76056.1 - 0.079 12.1 0.0 0.56 9.3 0.0 2.4 3 0 0 3 3 3 0 PhoH-like protein AAA_19 PF13245.1 EIW76056.1 - 0.12 12.1 0.0 0.45 10.3 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain Abhydrolase_6 PF12697.2 EIW76057.1 - 3.8e-12 46.5 0.1 5.8e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW76057.1 - 9.6e-11 41.6 0.0 2.9e-10 40.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Catalase PF00199.14 EIW76058.1 - 1.4e-179 596.7 0.3 1.8e-179 596.4 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EIW76058.1 - 4.9e-18 64.7 0.2 1.4e-17 63.2 0.0 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive RRM_1 PF00076.17 EIW76059.1 - 1.8e-18 65.9 0.0 2.7e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW76059.1 - 5.7e-14 51.8 0.0 9e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW76059.1 - 1.7e-12 46.9 0.0 2.5e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 EIW76059.1 - 0.0077 15.9 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif LDB19 PF13002.2 EIW76060.1 - 0.11 12.0 0.1 0.16 11.4 0.1 1.6 1 1 0 1 1 1 0 Arrestin_N terminal like zf-C2H2_4 PF13894.1 EIW76061.1 - 0.0037 17.4 7.0 0.56 10.6 0.2 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIW76061.1 - 0.0073 16.5 9.7 0.15 12.4 2.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EIW76061.1 - 0.48 10.6 4.2 0.6 10.3 0.9 2.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding PBP1_TM PF14812.1 EIW76061.1 - 0.84 9.9 13.0 0.075 13.3 3.3 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Myosin_head PF00063.16 EIW76062.1 - 1.7e-236 786.5 0.0 1.7e-236 786.5 0.0 4.0 3 1 1 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 EIW76062.1 - 7e-32 110.1 249.2 3.7e-18 64.6 82.7 6.0 2 2 1 3 3 3 2 Myosin tail Myosin_N PF02736.14 EIW76062.1 - 2.9e-08 33.2 0.1 8.5e-08 31.7 0.1 1.8 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.1 EIW76062.1 - 0.019 15.1 0.0 0.019 15.1 0.0 6.2 6 1 1 7 7 7 0 AAA domain Peptidase_M50 PF02163.17 EIW76063.1 - 3.3e-14 52.2 0.0 4.1e-13 48.7 0.0 2.2 1 1 0 1 1 1 1 Peptidase family M50 Longin PF13774.1 EIW76064.1 - 4.7e-16 58.1 0.1 8.1e-16 57.3 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EIW76064.1 - 1e-14 53.8 1.1 2e-14 52.9 0.7 1.4 1 0 0 1 1 1 1 Synaptobrevin Imm43 PF15602.1 EIW76064.1 - 0.08 12.9 0.1 1.6 8.6 0.0 2.1 2 0 0 2 2 2 0 Immunity protein 43 Glyco_hydro_16 PF00722.16 EIW76065.1 - 5.2e-17 61.7 1.0 1.2e-16 60.4 0.4 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Glyco_trans_2_3 PF13632.1 EIW76066.1 - 2.2e-51 174.3 0.1 2.2e-51 174.3 0.1 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIW76066.1 - 7.3e-11 42.2 0.0 4.4e-10 39.7 0.1 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EIW76066.1 - 0.0002 21.0 0.0 0.091 12.4 0.0 3.3 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIW76066.1 - 0.056 12.7 0.0 0.14 11.3 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 21 vATP-synt_E PF01991.13 EIW76067.1 - 4.2e-53 179.5 10.4 4.9e-53 179.3 7.2 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF883 PF05957.8 EIW76067.1 - 1.3 9.5 7.0 1.1 9.7 2.5 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) F-box-like PF12937.2 EIW76068.1 - 0.0044 16.7 0.2 0.0098 15.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like EzrA PF06160.7 EIW76068.1 - 0.13 10.4 0.0 0.17 10.0 0.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA LPP PF04728.8 EIW76068.1 - 0.13 12.0 0.5 11 5.9 0.1 2.2 2 0 0 2 2 2 0 Lipoprotein leucine-zipper F-box PF00646.28 EIW76068.1 - 1 9.0 6.1 0.091 12.4 0.7 2.0 2 0 0 2 2 2 0 F-box domain Glyco_hyd_65N_2 PF14498.1 EIW76069.1 - 5.6e-44 150.5 0.1 7.9e-44 150.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Ten1_2 PF15490.1 EIW76070.1 - 0.11 12.1 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Telomere-capping, CST complex subunit Ras PF00071.17 EIW76071.1 - 2.1e-34 118.2 0.3 2.6e-34 117.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW76071.1 - 1.4e-23 83.6 0.1 8.1e-23 81.1 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIW76071.1 - 5.9e-08 32.1 0.1 7.5e-08 31.8 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW76071.1 - 1.2e-07 31.1 0.2 1.5e-07 30.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EIW76071.1 - 0.0087 16.0 0.0 0.013 15.4 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EIW76071.1 - 0.015 14.0 0.4 0.029 13.0 0.0 1.6 2 1 0 2 2 2 0 G-protein alpha subunit PduV-EutP PF10662.4 EIW76071.1 - 0.091 12.2 0.3 0.44 10.0 0.2 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation DUF4267 PF14087.1 EIW76073.1 - 9.6e-29 99.2 1.3 1.1e-28 99.0 0.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF4267 PF14087.1 EIW76074.1 - 9.3e-28 96.0 6.2 1.1e-27 95.8 4.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) DUF4345 PF14248.1 EIW76074.1 - 0.3 10.5 5.4 0.37 10.2 3.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4345) PGPGW PF09656.5 EIW76074.1 - 1.2 8.5 8.3 1.9 7.8 0.3 3.0 3 0 0 3 3 3 0 Putative transmembrane protein (PGPGW) SNARE_assoc PF09335.6 EIW76077.1 - 1.1e-18 67.5 5.1 1.1e-18 67.5 3.5 2.0 3 0 0 3 3 3 1 SNARE associated Golgi protein GP41 PF00517.12 EIW76077.1 - 2.3 7.7 5.0 1 8.9 0.3 2.4 3 0 0 3 3 3 0 Retroviral envelope protein NAD_binding_6 PF08030.7 EIW76078.1 - 4.9e-18 65.5 0.0 7.8e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EIW76078.1 - 9.6e-18 63.9 0.0 2.4e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EIW76078.1 - 3.1e-12 46.6 11.6 3.1e-12 46.6 8.1 2.2 1 1 1 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EIW76078.1 - 0.0036 17.8 0.0 0.071 13.6 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain GATase PF00117.23 EIW76079.1 - 7.8e-13 48.3 0.0 1.3e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EIW76079.1 - 0.00042 19.8 0.0 0.00089 18.7 0.0 1.5 1 1 0 1 1 1 1 Peptidase C26 DJ-1_PfpI PF01965.19 EIW76079.1 - 0.026 13.9 0.0 0.038 13.4 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family HTS PF04204.11 EIW76079.1 - 0.073 11.7 0.2 0.28 9.8 0.0 2.0 2 1 1 3 3 3 0 Homoserine O-succinyltransferase CUE PF02845.11 EIW76080.1 - 3e-13 48.9 0.0 4.9e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 CUE domain GH3 PF03321.8 EIW76081.1 - 1.7e-56 191.8 0.0 3.2e-56 190.9 0.0 1.3 1 0 0 1 1 1 1 GH3 auxin-responsive promoter Pkinase PF00069.20 EIW76082.1 - 2e-70 236.8 0.0 2.7e-70 236.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW76082.1 - 1.4e-35 122.6 0.0 1.9e-35 122.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EIW76082.1 - 1.6e-10 41.3 2.6 4e-10 40.0 1.8 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EIW76082.1 - 0.00012 21.1 0.0 0.00026 20.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIW76082.1 - 0.00023 20.9 0.0 0.00051 19.8 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EIW76082.1 - 0.036 13.1 0.0 0.062 12.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Macro_2 PF14519.1 EIW76083.1 - 5.2e-09 35.6 0.0 7.7e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Macro-like domain Macro PF01661.16 EIW76083.1 - 0.093 12.6 0.0 3 7.7 0.0 2.3 2 0 0 2 2 2 0 Macro domain SNARE_assoc PF09335.6 EIW76084.1 - 9.6e-17 61.3 4.9 9.6e-17 61.3 3.4 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF2976 PF11190.3 EIW76084.1 - 0.17 11.4 9.8 0.23 11.0 0.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) Rhabdo_glycop PF00974.13 EIW76084.1 - 0.29 9.3 1.4 0.5 8.5 0.1 1.9 2 0 0 2 2 2 0 Rhabdovirus spike glycoprotein PDR_CDR PF06422.7 EIW76084.1 - 0.36 10.5 0.0 0.36 10.5 0.0 2.9 3 1 0 3 3 3 0 CDR ABC transporter DUF3671 PF12420.3 EIW76084.1 - 7.8 6.5 8.8 3.6 7.6 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function Glyoxal_oxid_N PF07250.6 EIW76086.1 - 6.2e-36 123.6 0.1 7.5e-32 110.3 0.0 3.8 3 1 0 3 3 3 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EIW76086.1 - 8.8e-21 73.8 0.5 2e-20 72.7 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Herpes_gE PF02480.11 EIW76086.1 - 0.00049 18.4 0.0 0.00074 17.8 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Kelch_4 PF13418.1 EIW76086.1 - 0.012 15.3 15.1 1.1 9.1 0.1 5.7 5 0 0 5 5 5 0 Galactose oxidase, central domain Arf PF00025.16 EIW76087.1 - 6.1e-71 237.2 0.0 7.3e-71 236.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EIW76087.1 - 1.2e-13 50.5 0.4 3.7e-09 35.7 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EIW76087.1 - 3.6e-13 49.1 0.0 5.1e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EIW76087.1 - 1.5e-10 40.7 0.0 1.6e-10 40.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EIW76087.1 - 1.7e-10 40.4 0.0 2.1e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EIW76087.1 - 1.8e-08 34.9 0.0 2.4e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIW76087.1 - 3.7e-05 23.6 0.0 5.4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIW76087.1 - 0.012 15.0 0.0 0.076 12.4 0.0 2.0 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain WD40 PF00400.27 EIW76088.1 - 1.6e-33 113.3 22.3 2.5e-12 46.1 2.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EIW76088.1 - 2.1e-05 23.4 0.7 0.012 14.3 0.1 2.4 1 1 0 2 2 2 2 Nup133 N terminal like eIF2A PF08662.6 EIW76088.1 - 0.0026 17.5 0.0 0.0081 15.8 0.0 1.8 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Big_2 PF02368.13 EIW76088.1 - 0.14 12.0 0.6 0.39 10.6 0.1 1.9 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) Iso_dh PF00180.15 EIW76089.1 - 3.9e-98 328.6 0.0 4.5e-98 328.3 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase GAS2 PF02187.12 EIW76091.1 - 1.5e-08 34.2 0.0 4.8e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Prok-RING_1 PF14446.1 EIW76092.1 - 0.007 16.0 2.0 0.0097 15.6 0.3 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 DZR PF12773.2 EIW76092.1 - 0.023 14.5 1.2 0.029 14.1 0.1 1.7 2 0 0 2 2 2 0 Double zinc ribbon DUF904 PF06005.7 EIW76093.1 - 0.073 13.3 8.9 0.15 12.3 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) EzrA PF06160.7 EIW76093.1 - 0.081 11.0 4.2 0.11 10.6 2.9 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA CENP-Q PF13094.1 EIW76093.1 - 0.62 10.0 10.7 0.083 12.9 4.4 1.7 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Spc97_Spc98 PF04130.8 EIW76095.1 - 1.3e-112 376.9 0.0 2.8e-112 375.8 0.0 1.6 2 0 0 2 2 2 1 Spc97 / Spc98 family RE_HaeII PF09554.5 EIW76095.1 - 0.026 13.5 0.0 0.044 12.7 0.0 1.2 1 0 0 1 1 1 0 HaeII restriction endonuclease DUF615 PF04751.9 EIW76095.1 - 0.041 13.5 1.0 2.4 7.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF615) RasGAP_C PF03836.10 EIW76096.1 - 4.7e-38 130.0 2.6 1.4e-37 128.5 1.8 1.9 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 EIW76096.1 - 3.7e-35 121.3 1.4 3.7e-34 118.1 0.0 2.4 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 EIW76096.1 - 1.3e-21 74.1 56.0 0.03 13.9 0.9 14.0 13 0 0 13 13 13 8 IQ calmodulin-binding motif CH PF00307.26 EIW76096.1 - 4.3e-09 36.3 0.0 1.6e-08 34.5 0.0 2.1 1 0 0 1 1 1 1 Calponin homology (CH) domain Sipho_Gp157 PF05565.6 EIW76096.1 - 0.022 14.3 1.4 0.073 12.6 1.0 1.9 1 0 0 1 1 1 0 Siphovirus Gp157 IncA PF04156.9 EIW76096.1 - 0.064 12.8 9.7 0.37 10.3 2.0 3.6 3 0 0 3 3 3 0 IncA protein FF PF01846.14 EIW76097.1 - 1.6e-34 117.5 18.2 4.3e-09 36.1 0.0 6.1 6 0 0 6 6 6 5 FF domain WW PF00397.21 EIW76097.1 - 6e-10 38.8 8.1 3e-07 30.1 2.0 2.6 2 0 0 2 2 2 2 WW domain Senescence_reg PF04520.8 EIW76097.1 - 3.7 8.0 26.8 0.032 14.7 7.1 3.4 2 1 1 3 3 3 0 Senescence regulator HSP90 PF00183.13 EIW76098.1 - 1.7e-122 409.5 2.6 2.2e-122 409.2 1.8 1.0 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EIW76098.1 - 5.5e-11 42.2 0.2 1.9e-10 40.5 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EIW76098.1 - 9.8e-07 28.4 0.0 2.2e-06 27.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CRCB PF02537.10 EIW76098.1 - 0.21 11.4 0.0 0.51 10.2 0.0 1.6 1 0 0 1 1 1 0 CrcB-like protein Kelch_3 PF13415.1 EIW76099.1 - 7e-17 61.0 19.2 2.3e-05 24.4 0.1 6.8 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.1 EIW76099.1 - 8.4e-16 57.4 14.3 3.1e-05 23.6 0.3 6.0 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EIW76099.1 - 7.9e-11 41.6 6.4 0.00083 19.2 0.1 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 EIW76099.1 - 3.3e-06 27.0 6.8 0.27 11.4 0.0 5.0 4 1 0 4 4 4 2 Kelch motif Kelch_1 PF01344.20 EIW76099.1 - 1.4e-05 24.5 5.3 2.2 7.8 0.1 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 EIW76099.1 - 0.0028 17.3 1.5 1.4 8.8 0.1 4.8 5 0 0 5 5 5 1 Kelch motif Hanta_G1 PF01567.11 EIW76099.1 - 1.3 7.2 1.7 2 6.5 1.2 1.2 1 0 0 1 1 1 0 Hantavirus glycoprotein G1 ORC6 PF05460.8 EIW76100.1 - 0.094 11.7 1.7 0.093 11.8 1.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) zf-C2H2_4 PF13894.1 EIW76101.1 - 1.6e-05 24.8 14.2 0.00018 21.5 0.5 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIW76101.1 - 3.4e-05 23.9 14.7 0.0008 19.6 1.0 3.6 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW76101.1 - 3.8e-05 23.7 17.0 0.0019 18.3 0.4 3.2 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 EIW76101.1 - 0.00055 20.0 0.6 0.0019 18.3 0.4 2.0 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIW76101.1 - 0.081 13.0 0.2 0.081 13.0 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EIW76101.1 - 0.2 11.9 0.3 0.2 11.9 0.2 3.3 3 1 0 3 3 3 0 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 EIW76101.1 - 0.6 10.2 8.1 1.2 9.2 2.5 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Cid2 PF09774.4 EIW76102.1 - 1.5e-28 99.7 2.5 2.5e-28 99.1 1.8 1.3 1 0 0 1 1 1 1 Caffeine-induced death protein 2 DUF1554 PF07588.6 EIW76102.1 - 0.034 13.6 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1554) GILT PF03227.11 EIW76103.1 - 2.1e-10 40.3 0.2 2.1e-10 40.3 0.2 1.6 2 0 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Yos1 PF08571.5 EIW76104.1 - 4.3e-25 87.6 2.9 1.8e-20 72.7 0.0 2.1 1 1 1 2 2 2 2 Yos1-like Ribosomal_L22 PF00237.14 EIW76105.1 - 8e-20 70.7 0.4 1.2e-19 70.1 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Ribophorin_I PF04597.9 EIW76106.1 - 3.8e-119 398.0 0.7 4.2e-119 397.8 0.5 1.0 1 0 0 1 1 1 1 Ribophorin I Asp PF00026.18 EIW76108.1 - 5.9e-39 134.1 4.1 8.6e-39 133.6 2.9 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW76108.1 - 4e-05 23.6 1.1 0.0003 20.7 0.0 2.9 3 1 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIW76108.1 - 0.0051 17.2 0.1 12 6.5 0.0 3.4 3 0 0 3 3 3 1 Aspartyl protease gag-asp_proteas PF13975.1 EIW76108.1 - 0.014 15.1 0.1 5.5 6.8 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Herpes_gE PF02480.11 EIW76108.1 - 0.015 13.5 0.1 0.023 12.9 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TAXi_C PF14541.1 EIW76108.1 - 0.058 12.9 0.1 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal TMEM154 PF15102.1 EIW76108.1 - 0.14 11.8 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family Shisa PF13908.1 EIW76108.1 - 0.14 12.2 0.1 0.3 11.2 0.1 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator IncA PF04156.9 EIW76108.1 - 0.29 10.7 0.2 0.43 10.1 0.1 1.2 1 0 0 1 1 1 0 IncA protein Fe-ADH PF00465.14 EIW76109.1 - 8.9e-91 304.2 0.0 1.2e-90 303.8 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EIW76109.1 - 1.5e-12 47.3 0.0 1.5e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase zf-Nse PF11789.3 EIW76109.1 - 0.043 13.3 0.3 0.12 11.9 0.2 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit His_biosynth PF00977.16 EIW76110.1 - 5.8e-35 120.6 0.0 7.2e-35 120.3 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribosomal_L29 PF00831.18 EIW76111.1 - 7e-20 70.4 3.3 7e-20 70.4 2.3 2.1 2 1 1 3 3 3 1 Ribosomal L29 protein Ribosomal_S9 PF00380.14 EIW76111.1 - 0.0052 17.0 1.9 0.0073 16.5 1.3 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 MRP-L47 PF06984.8 EIW76111.1 - 0.06 13.2 2.4 0.13 12.2 1.4 1.7 1 1 0 1 1 1 0 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) HLH PF00010.21 EIW76111.1 - 0.11 12.1 0.5 0.11 12.1 0.3 2.4 2 1 0 2 2 2 0 Helix-loop-helix DNA-binding domain DUF3698 PF12479.3 EIW76111.1 - 0.14 12.2 6.5 2.2 8.4 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3698) Phasin PF05597.6 EIW76111.1 - 0.29 10.9 4.4 0.17 11.6 2.0 1.4 1 1 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) FliT PF05400.8 EIW76111.1 - 0.44 10.9 5.4 2.2 8.7 0.2 2.3 2 0 0 2 2 2 0 Flagellar protein FliT DUF1844 PF08899.6 EIW76111.1 - 0.54 10.2 4.5 0.91 9.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1844) Phospholamban PF04272.9 EIW76111.1 - 0.8 9.2 3.4 0.22 11.0 0.2 1.6 2 0 0 2 2 2 0 Phospholamban Pkinase PF00069.20 EIW76112.1 - 3e-69 233.0 0.0 4.2e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW76112.1 - 2.4e-48 164.4 0.0 3.5e-48 163.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW76112.1 - 9.7e-07 28.0 0.0 8.4e-05 21.6 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Polysacc_deac_1 PF01522.16 EIW76113.1 - 1.2e-23 83.0 0.0 2.3e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase HLH PF00010.21 EIW76114.1 - 5e-13 48.5 0.2 1.3e-12 47.2 0.1 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain AAA_16 PF13191.1 EIW76114.1 - 0.0021 18.0 0.0 0.0078 16.2 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EIW76114.1 - 0.0049 17.0 0.2 0.027 14.6 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EIW76114.1 - 0.028 13.0 0.0 0.052 12.2 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EIW76114.1 - 0.09 13.5 0.1 0.48 11.2 0.0 2.3 1 0 0 1 1 1 0 AAA domain Cupin_8 PF13621.1 EIW76115.1 - 1.1e-57 195.3 0.0 1.5e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EIW76115.1 - 0.0097 16.1 0.1 0.029 14.6 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase RFX_DNA_binding PF02257.10 EIW76116.1 - 1.4e-25 89.1 0.0 2.8e-25 88.2 0.0 1.5 1 0 0 1 1 1 1 RFX DNA-binding domain AMP-binding PF00501.23 EIW76117.1 - 2.5e-42 144.7 0.0 3.5e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MARVEL PF01284.18 EIW76118.1 - 0.13 12.0 15.4 0.23 11.2 9.6 2.0 1 1 2 3 3 3 0 Membrane-associating domain UQ_con PF00179.21 EIW76119.1 - 2.3e-36 124.2 0.1 2.8e-36 124.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme G6PD_C PF02781.11 EIW76120.1 - 1.3e-125 418.1 0.0 1.7e-125 417.7 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EIW76120.1 - 8.1e-62 208.7 0.0 1.2e-61 208.1 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain DUF1682 PF07946.9 EIW76122.1 - 4.6e-65 219.5 0.0 5.2e-65 219.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF4245 PF14030.1 EIW76123.1 - 0.037 13.7 0.0 0.045 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4245) DUF3818 PF12825.2 EIW76124.1 - 4.4e-115 384.0 0.1 5.6e-115 383.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EIW76124.1 - 4.9e-28 97.4 0.1 1.1e-27 96.2 0.1 1.6 1 0 0 1 1 1 1 PX-associated PX PF00787.19 EIW76124.1 - 6e-12 45.3 0.4 3.1e-11 43.0 0.1 2.4 2 0 0 2 2 2 1 PX domain Hormone_1 PF00103.15 EIW76124.1 - 0.1 11.9 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Somatotropin hormone family SMN PF06003.7 EIW76124.1 - 0.18 10.9 9.0 0.36 9.9 6.3 1.4 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) Pkinase PF00069.20 EIW76125.1 - 5.4e-64 215.8 0.2 3.9e-42 144.2 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW76125.1 - 7.9e-31 107.0 0.3 1.1e-22 80.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EIW76125.1 - 2.4e-05 23.5 0.0 5.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EIW76125.1 - 0.00046 19.2 0.7 0.0015 17.5 0.0 2.2 2 1 0 2 2 2 1 Kinase-like APH PF01636.18 EIW76125.1 - 0.0045 16.7 0.0 0.029 14.0 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EIW76125.1 - 0.0074 15.1 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Seadorna_VP7 PF07387.6 EIW76125.1 - 0.031 13.1 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.17 EIW76125.1 - 0.034 13.4 0.0 0.067 12.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_C PF00433.19 EIW76125.1 - 0.07 13.6 0.4 0.18 12.3 0.3 1.7 1 0 0 1 1 1 0 Protein kinase C terminal domain BCDHK_Adom3 PF10436.4 EIW76126.1 - 2.3e-42 144.2 0.1 3.2e-42 143.8 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EIW76126.1 - 7.6e-12 44.9 0.0 5e-11 42.3 0.0 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EIW76126.1 - 0.0087 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Med20 PF08612.6 EIW76127.1 - 3.7e-09 36.0 0.0 6.3e-09 35.3 0.0 1.4 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex ORC4_C PF14629.1 EIW76128.1 - 4.7e-28 97.9 0.0 8.8e-28 97.0 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.1 EIW76128.1 - 1.3e-17 64.3 0.1 3.5e-17 63.0 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW76128.1 - 6.8e-05 23.0 0.0 0.00016 21.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EIW76128.1 - 0.0011 18.6 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EIW76128.1 - 0.003 17.2 0.0 0.0092 15.6 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA PF00004.24 EIW76128.1 - 0.0031 17.6 0.0 0.017 15.3 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ATP-synt_ab PF00006.20 EIW76128.1 - 0.021 14.3 0.0 0.047 13.1 0.0 1.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_33 PF13671.1 EIW76128.1 - 0.032 14.0 0.0 0.084 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EIW76128.1 - 0.048 13.0 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EIW76128.1 - 0.056 12.3 0.1 0.27 10.1 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 EIW76128.1 - 0.1 12.8 0.0 0.28 11.4 0.0 1.7 1 1 0 1 1 1 0 ABC transporter RNA12 PF10443.4 EIW76128.1 - 0.21 10.0 0.0 0.32 9.4 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein DUF3759 PF12585.3 EIW76129.1 - 4.7e-36 122.5 5.7 5.8e-36 122.2 3.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) RNA_pol_I_A49 PF06870.7 EIW76129.1 - 0.0091 14.6 0.4 0.0092 14.5 0.3 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor DUF3336 PF11815.3 EIW76130.1 - 2.4e-39 134.1 1.8 3.8e-39 133.5 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EIW76130.1 - 1.6e-20 73.9 0.2 3.6e-20 72.7 0.2 1.7 1 0 0 1 1 1 1 Patatin-like phospholipase PUB PF09409.5 EIW76131.1 - 2.1e-09 37.0 0.0 3.7e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 PUB domain dsDNA_bind PF01984.15 EIW76131.1 - 0.34 10.9 8.2 0.1 12.6 3.4 1.8 2 0 0 2 2 2 0 Double-stranded DNA-binding domain PCI PF01399.22 EIW76133.1 - 1.9e-11 44.1 0.0 1.9e-10 40.9 0.0 2.6 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.4 EIW76133.1 - 0.029 13.7 0.1 0.065 12.6 0.0 1.7 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_11 PF13414.1 EIW76133.1 - 0.049 13.2 3.4 1.5 8.4 0.2 2.5 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.1 EIW76133.1 - 0.051 14.2 0.2 6.9 7.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M13_N PF05649.8 EIW76133.1 - 0.066 12.2 0.9 0.11 11.5 0.6 1.2 1 0 0 1 1 1 0 Peptidase family M13 TPR_12 PF13424.1 EIW76133.1 - 0.11 12.3 5.0 0.3 11.0 0.7 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EIW76133.1 - 2.8 8.3 5.8 3.3 8.1 0.2 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.20 EIW76134.1 - 1.1e-75 254.1 0.0 1.4e-75 253.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW76134.1 - 1.7e-38 132.1 0.0 2.4e-38 131.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW76134.1 - 3.8e-07 29.3 0.0 2.1e-06 26.9 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EIW76134.1 - 0.086 11.9 0.1 0.25 10.3 0.1 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family WD40 PF00400.27 EIW76136.1 - 7e-22 76.4 2.9 1.8e-06 27.5 0.6 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat Asp PF00026.18 EIW76137.1 - 3e-113 378.2 0.3 3.5e-113 378.0 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW76137.1 - 5.6e-10 39.4 0.0 1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIW76137.1 - 2.7e-06 27.0 0.0 6.3e-05 22.5 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EIW76137.1 - 2.7e-06 27.7 0.0 0.007 16.8 0.0 2.6 2 0 0 2 2 2 2 Aspartyl protease Bromodomain PF00439.20 EIW76138.1 - 4.9e-25 87.2 0.3 9.2e-25 86.3 0.2 1.4 1 0 0 1 1 1 1 Bromodomain Myb_DNA-binding PF00249.26 EIW76138.1 - 0.0049 16.8 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF605 PF04652.11 EIW76138.1 - 0.011 15.1 20.3 0.015 14.6 14.1 1.1 1 0 0 1 1 1 0 Vta1 like FAT PF02259.18 EIW76139.1 - 5.9e-70 236.0 5.1 1.3e-69 234.9 3.5 1.6 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.22 EIW76139.1 - 3.9e-18 65.8 0.0 9.6e-18 64.5 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EIW76139.1 - 6.5e-05 22.2 0.0 0.00015 21.1 0.0 1.7 1 0 0 1 1 1 1 FATC domain TPR_11 PF13414.1 EIW76139.1 - 0.00072 19.1 2.2 0.015 14.9 0.5 2.8 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EIW76139.1 - 0.059 13.3 1.6 14 5.8 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat WH2 PF02205.15 EIW76141.1 - 2.3e-07 30.2 2.6 3.2e-07 29.7 0.7 2.1 2 0 0 2 2 2 1 WH2 motif Thioredoxin PF00085.15 EIW76142.1 - 2.8e-59 197.2 0.7 1.6e-29 101.6 0.0 4.0 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 EIW76142.1 - 1.6e-45 155.1 0.3 6.9e-36 123.7 0.1 3.1 2 1 1 3 3 3 2 Thioredoxin-like domain Calsequestrin PF01216.12 EIW76142.1 - 2.4e-09 36.4 0.4 2.4e-09 36.4 0.3 1.6 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_7 PF13899.1 EIW76142.1 - 4.9e-09 36.1 0.3 0.0029 17.6 0.0 3.1 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EIW76142.1 - 9.5e-09 35.2 1.4 0.007 16.4 0.0 4.1 4 1 1 5 5 5 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EIW76142.1 - 4.2e-08 33.3 0.7 0.013 15.6 0.1 3.8 2 2 0 2 2 2 2 Thioredoxin-like domain AhpC-TSA PF00578.16 EIW76142.1 - 1.5e-06 27.9 0.3 0.011 15.4 0.0 3.3 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.5 EIW76142.1 - 1.7e-06 27.6 0.7 0.19 11.2 0.0 3.4 3 0 0 3 3 3 2 Redoxin Thioredoxin_4 PF13462.1 EIW76142.1 - 0.01 15.8 0.6 7.6 6.5 0.1 3.8 3 1 1 4 4 4 0 Thioredoxin Glutaredoxin PF00462.19 EIW76142.1 - 0.02 14.8 1.0 4.1 7.4 0.0 3.1 2 1 0 2 2 2 0 Glutaredoxin Thioredoxin_3 PF13192.1 EIW76142.1 - 0.061 13.1 0.0 0.74 9.6 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin domain TCTP PF00838.12 EIW76143.1 - 8.7e-71 237.2 1.0 9.7e-71 237.0 0.7 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein NAGidase PF07555.8 EIW76143.1 - 0.049 12.5 0.1 0.062 12.1 0.1 1.1 1 0 0 1 1 1 0 beta-N-acetylglucosaminidase Tim44 PF04280.10 EIW76143.1 - 0.091 12.7 0.3 0.59 10.1 0.0 2.0 1 1 1 2 2 2 0 Tim44-like domain UTP15_C PF09384.5 EIW76144.1 - 5e-48 162.5 0.1 8.6e-48 161.7 0.1 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EIW76144.1 - 6.3e-29 98.7 3.0 4.1e-07 29.6 0.0 6.4 6 1 0 6 6 6 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EIW76144.1 - 0.00069 18.0 0.0 0.69 8.1 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Coatomer_WDAD PF04053.9 EIW76144.1 - 0.00089 18.1 0.0 0.055 12.2 0.0 2.1 2 0 0 2 2 2 2 Coatomer WD associated region CTNNBL PF08216.6 EIW76145.1 - 2.2e-29 101.1 0.4 8.4e-29 99.3 0.0 2.2 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear UNC45-central PF11701.3 EIW76145.1 - 0.0022 17.6 2.4 1.6 8.3 0.0 3.7 2 1 2 4 4 4 2 Myosin-binding striated muscle assembly central Arm PF00514.18 EIW76145.1 - 0.0042 16.8 0.0 0.023 14.5 0.0 2.3 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EIW76145.1 - 0.021 15.0 2.3 0.26 11.5 0.5 3.1 3 0 0 3 3 3 0 HEAT repeats Mo25 PF08569.6 EIW76145.1 - 0.048 12.6 0.6 0.43 9.5 0.1 2.3 2 0 0 2 2 2 0 Mo25-like RRM_1 PF00076.17 EIW76146.1 - 2.8e-15 55.7 0.0 4e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW76146.1 - 8.5e-11 41.6 0.0 1.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW76146.1 - 0.00081 19.1 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_L18p PF00861.17 EIW76147.1 - 3.3e-42 143.4 0.0 6.3e-42 142.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EIW76147.1 - 3e-32 111.0 2.4 3e-32 111.0 1.7 1.9 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Peripla_BP_5 PF13433.1 EIW76147.1 - 0.053 12.2 0.0 0.085 11.5 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein domain Med17 PF10156.4 EIW76148.1 - 1.9e-47 161.5 0.0 2.9e-47 161.0 0.0 1.3 1 0 0 1 1 1 1 Subunit 17 of Mediator complex Fungal_trans PF04082.13 EIW76149.1 - 1.8e-19 69.6 0.3 3e-19 68.9 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW76149.1 - 8.3e-06 25.6 9.8 1.5e-05 24.8 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CCHC_3 PF13917.1 EIW76150.1 - 0.0014 18.3 25.7 0.12 12.1 1.7 4.4 3 1 1 4 4 4 4 Zinc knuckle zf-CCHC PF00098.18 EIW76150.1 - 0.07 13.0 37.7 0.027 14.4 5.1 4.8 5 0 0 5 5 5 0 Zinc knuckle FAM220 PF15487.1 EIW76150.1 - 5.9 6.1 7.9 2.4 7.4 3.5 1.7 2 0 0 2 2 2 0 FAM220 family DUF2435 PF10363.4 EIW76151.1 - 3.6e-29 100.5 0.1 1.6e-28 98.4 0.0 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2435) HEAT PF02985.17 EIW76151.1 - 0.0066 16.4 0.7 21 5.5 0.0 4.7 4 0 0 4 4 4 2 HEAT repeat DUF2411 PF10304.4 EIW76151.1 - 0.035 13.6 1.0 0.098 12.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2411) HEAT_EZ PF13513.1 EIW76151.1 - 6.9 7.3 17.5 5.7 7.5 0.4 6.7 7 1 1 8 8 8 0 HEAT-like repeat UQ_con PF00179.21 EIW76152.1 - 8.9e-17 60.8 0.1 1.1e-16 60.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EIW76152.1 - 0.0011 18.7 0.0 0.0014 18.4 0.0 1.3 1 0 0 1 1 1 1 RWD domain DUF3454 PF11936.3 EIW76152.1 - 0.092 12.9 1.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3454) His_Phos_2 PF00328.17 EIW76153.1 - 9.8e-84 281.6 0.1 1.5e-83 280.9 0.1 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EIW76153.1 - 2.4e-06 27.1 0.0 4.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain E1-E2_ATPase PF00122.15 EIW76154.1 - 7.7e-45 152.6 0.1 1.9e-43 148.1 0.0 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EIW76154.1 - 7.4e-43 147.4 0.1 1.1e-42 146.8 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EIW76154.1 - 4.2e-26 90.8 0.2 3.3e-10 39.9 0.2 3.5 3 0 0 3 3 3 3 Heavy-metal-associated domain HAD PF12710.2 EIW76154.1 - 3.5e-14 53.4 0.0 7.3e-14 52.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIW76154.1 - 0.00092 18.8 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Amidohydro_4 PF13147.1 EIW76155.1 - 6.3e-08 32.9 0.3 8.2e-08 32.6 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 EIW76155.1 - 1.5e-07 31.2 0.0 2e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Kinesin PF00225.18 EIW76156.1 - 5.7e-106 353.9 0.0 1.2e-105 352.9 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Spc7 PF08317.6 EIW76156.1 - 2.3 6.8 7.5 1.7 7.2 2.2 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.1 EIW76156.1 - 2.3 6.5 8.7 0.17 10.3 2.2 1.7 2 0 0 2 2 2 0 AAA domain EMP24_GP25L PF01105.19 EIW76157.1 - 5.9e-52 176.0 1.3 7.1e-52 175.7 0.9 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD AAA_2 PF07724.9 EIW76158.1 - 9.9e-38 129.7 0.0 1.8e-37 128.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EIW76158.1 - 1.6e-14 54.1 0.0 2.9e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EIW76158.1 - 1.9e-10 40.4 0.0 5.2e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EIW76158.1 - 2.1e-05 24.2 0.0 5.4e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EIW76158.1 - 7.7e-05 22.8 0.1 0.0012 18.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW76158.1 - 7.9e-05 23.4 0.0 0.00016 22.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW76158.1 - 0.00016 21.7 0.1 0.00057 19.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.16 EIW76158.1 - 0.00017 20.8 0.0 0.0041 16.3 0.0 2.7 2 1 1 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 EIW76158.1 - 0.00028 20.4 0.0 0.19 11.1 0.0 2.8 2 1 1 3 3 3 1 AAA-like domain T2SE PF00437.15 EIW76158.1 - 0.002 17.1 0.0 0.0033 16.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_33 PF13671.1 EIW76158.1 - 0.0023 17.8 0.0 0.0051 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EIW76158.1 - 0.0031 17.0 0.0 0.0087 15.5 0.0 1.6 2 0 0 2 2 1 1 DEAD/DEAH box helicase IstB_IS21 PF01695.12 EIW76158.1 - 0.0035 16.7 0.0 0.0085 15.5 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EIW76158.1 - 0.0066 16.1 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EIW76158.1 - 0.0084 15.1 0.0 0.13 11.2 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 EIW76158.1 - 0.012 15.1 0.0 0.088 12.2 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.22 EIW76158.1 - 0.013 15.7 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter PhoH PF02562.11 EIW76158.1 - 0.014 14.6 0.0 0.034 13.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_24 PF13479.1 EIW76158.1 - 0.016 14.7 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EIW76158.1 - 0.023 14.7 0.0 0.051 13.6 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_14 PF13173.1 EIW76158.1 - 0.024 14.5 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIW76158.1 - 0.026 14.8 0.0 0.058 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EIW76158.1 - 0.027 13.9 0.2 0.075 12.4 0.1 1.7 1 1 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 EIW76158.1 - 0.032 13.7 0.0 0.078 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_3 PF07726.6 EIW76158.1 - 0.034 13.7 0.0 0.79 9.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EIW76158.1 - 0.038 13.6 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain MobB PF03205.9 EIW76158.1 - 0.083 12.5 0.1 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EIW76158.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EIW76158.1 - 0.17 12.0 0.0 0.61 10.2 0.0 1.9 2 0 0 2 2 2 0 RNA helicase PGAMP PF07644.6 EIW76158.1 - 0.18 11.6 0.0 0.18 11.6 0.0 2.2 2 0 0 2 2 1 0 Planctomycete PGAMP ResIII PF04851.10 EIW76158.1 - 0.18 11.5 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Cactin_mid PF10312.4 EIW76159.1 - 2.5e-61 206.2 5.8 2.5e-61 206.2 4.0 2.7 3 0 0 3 3 3 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EIW76159.1 - 1.3e-57 192.8 6.4 2.4e-57 191.9 4.5 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cyclin PF08613.6 EIW76160.1 - 0.0019 18.6 0.1 0.004 17.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin ThiF PF00899.16 EIW76161.1 - 1.7e-50 170.3 0.0 3.8e-30 104.4 0.0 2.5 2 0 0 2 2 2 2 ThiF family UBA_e1_C PF09358.5 EIW76161.1 - 6.2e-46 155.6 0.1 1.7e-45 154.1 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EIW76161.1 - 3.7e-44 148.1 4.7 8.7e-28 95.6 0.1 4.5 5 0 0 5 5 5 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EIW76161.1 - 3.8e-22 77.3 0.9 2.5e-18 65.2 0.4 2.4 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Tenui_N PF05733.6 EIW76161.1 - 0.17 11.1 0.0 0.37 10.0 0.0 1.5 1 0 0 1 1 1 0 Tenuivirus/Phlebovirus nucleocapsid protein Cyclin PF08613.6 EIW76162.1 - 2.9e-09 37.4 0.0 5.5e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin DUF3402 PF11882.3 EIW76163.1 - 1.5e-115 386.5 0.5 2.8e-115 385.6 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EIW76163.1 - 1.5e-44 152.0 0.0 2.3e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 N1221-like protein Diphthamide_syn PF01866.12 EIW76164.1 - 2.4e-90 302.9 0.0 1.1e-33 116.8 0.2 3.9 3 1 0 3 3 3 3 Putative diphthamide synthesis protein Patched PF02460.13 EIW76165.1 - 7.2e-69 232.5 3.7 6.4e-64 216.2 4.5 3.0 2 1 0 2 2 2 2 Patched family Sterol-sensing PF12349.3 EIW76165.1 - 3.8e-47 159.5 15.3 4.4e-25 87.9 0.1 3.6 3 0 0 3 3 3 3 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 EIW76165.1 - 3.9e-07 27.9 4.0 5.9e-07 27.3 2.7 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.10 EIW76165.1 - 0.048 12.3 27.5 0.088 11.5 1.0 3.2 3 0 0 3 3 3 0 MMPL family zf-C2H2 PF00096.21 EIW76166.1 - 0.00056 20.0 4.2 0.00056 20.0 2.9 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW76166.1 - 0.0014 18.8 22.2 0.1 12.9 1.8 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met2 PF12907.2 EIW76166.1 - 0.28 11.1 3.3 2.4 8.1 0.4 2.5 2 0 0 2 2 2 0 Zinc-binding zf-C2H2_6 PF13912.1 EIW76166.1 - 0.28 11.1 0.2 0.28 11.1 0.2 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIW76166.1 - 0.29 11.5 0.3 0.29 11.5 0.2 3.6 4 0 0 4 4 4 0 Zinc-finger double domain FAD_binding_6 PF00970.19 EIW76167.1 - 4e-10 39.6 0.0 1.1e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EIW76167.1 - 4.1e-10 40.1 0.0 2e-05 25.1 0.0 2.3 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EIW76167.1 - 1.1e-07 31.8 0.0 5.2e-07 29.6 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EIW76167.1 - 0.028 14.3 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain p450 PF00067.17 EIW76168.1 - 5.4e-65 219.6 0.0 1.3e-64 218.4 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 DUF1736 PF08409.6 EIW76170.1 - 0.13 11.8 0.3 0.46 10.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1736) Med18 PF09637.5 EIW76173.1 - 3.7e-05 23.3 0.0 8e-05 22.3 0.0 1.4 1 1 0 2 2 2 1 Med18 protein Pro_isomerase PF00160.16 EIW76174.1 - 1.3e-36 126.1 0.0 2e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EIW76174.1 - 2.9e-15 55.6 0.0 5.3e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW76174.1 - 4.9e-11 42.4 0.0 1.2e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW76174.1 - 5.3e-09 35.7 0.1 9.4e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BTB PF00651.26 EIW76175.1 - 3.7e-12 46.1 0.0 8e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Aldedh PF00171.17 EIW76176.1 - 1.2e-104 350.2 0.0 1.6e-104 349.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4156 PF13698.1 EIW76176.1 - 0.041 13.7 0.2 9.5 6.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4156) DUF751 PF05421.6 EIW76177.1 - 5.3 7.4 10.1 7.6 6.9 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF751) GRAM PF02893.15 EIW76178.1 - 0.0035 16.8 0.0 0.0075 15.7 0.0 1.6 2 0 0 2 2 2 1 GRAM domain Vps36_ESCRT-II PF11605.3 EIW76178.1 - 0.0037 17.0 0.0 0.016 14.9 0.0 2.0 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 WWbp PF10349.4 EIW76178.1 - 0.017 15.9 0.8 0.061 14.2 0.6 1.9 1 1 0 1 1 1 0 WW-domain ligand protein Pkinase PF00069.20 EIW76179.1 - 1.5e-41 142.3 0.0 2.4e-24 85.8 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW76179.1 - 7.1e-14 51.4 0.0 5.7e-11 41.9 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EIW76179.1 - 0.00033 20.4 0.3 0.0019 17.9 0.1 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW76179.1 - 0.079 11.9 0.0 0.93 8.3 0.0 2.1 2 0 0 2 2 2 0 Kinase-like UCH PF00443.24 EIW76180.1 - 4.5e-32 111.2 0.0 1e-31 110.0 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW76180.1 - 2.3e-11 43.7 0.0 4e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF1992 PF09350.5 EIW76181.1 - 1e-18 66.8 0.3 2.4e-18 65.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) TRP PF06011.7 EIW76183.1 - 6.3e-43 146.9 28.2 2e-42 145.2 19.6 1.8 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel E1_DerP2_DerF2 PF02221.10 EIW76183.1 - 0.034 14.3 0.0 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 ML domain CNH PF00780.17 EIW76184.1 - 0.0085 15.5 0.0 0.15 11.4 0.0 2.2 2 0 0 2 2 2 1 CNH domain DUF1900 PF08954.6 EIW76184.1 - 0.17 11.4 0.0 0.35 10.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1900) SMK-1 PF04802.10 EIW76187.1 - 4.4e-64 215.5 4.7 5.5e-64 215.2 2.9 1.5 2 0 0 2 2 2 1 Component of IIS longevity pathway SMK-1 Pkinase PF00069.20 EIW76188.1 - 2.1e-40 138.5 0.0 2.9e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW76188.1 - 6.1e-15 54.9 0.0 8.4e-12 44.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EIW76188.1 - 1.9e-06 27.7 0.3 4.5e-06 26.5 0.2 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Glyco_hydro_53 PF07745.8 EIW76189.1 - 7.7e-73 245.1 0.2 9.5e-73 244.8 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Phospholamban PF04272.9 EIW76190.1 - 0.091 12.2 0.1 0.13 11.7 0.1 1.3 1 0 0 1 1 1 0 Phospholamban BPL_LplA_LipB PF03099.14 EIW76191.1 - 1.8e-18 66.7 0.0 3.6e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.4 EIW76191.1 - 2.9e-06 26.8 0.0 5.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus CHCH PF06747.8 EIW76193.1 - 0.0086 15.9 7.2 0.0086 15.9 5.0 2.5 3 0 0 3 3 3 2 CHCH domain YqzH PF14164.1 EIW76193.1 - 0.061 13.2 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 YqzH-like protein Pet191_N PF10203.4 EIW76193.1 - 3.1 7.9 11.6 1 9.4 3.8 2.6 1 1 2 3 3 3 0 Cytochrome c oxidase assembly protein PET191 DUF498 PF04430.9 EIW76195.1 - 6.3e-30 102.9 0.0 7.8e-30 102.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) MAS20 PF02064.10 EIW76196.1 - 2.1e-18 66.4 0.2 6.4e-18 64.8 0.1 1.9 1 1 0 1 1 1 1 MAS20 protein import receptor SET PF00856.23 EIW76196.1 - 2.5e-09 37.6 0.0 6.6e-07 29.7 0.0 2.5 2 0 0 2 2 2 2 SET domain DUF4500 PF14937.1 EIW76196.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) TB2_DP1_HVA22 PF03134.14 EIW76198.1 - 1.2e-11 44.1 0.5 3.8e-11 42.5 0.3 1.8 1 1 0 1 1 1 1 TB2/DP1, HVA22 family G10 PF01125.12 EIW76199.1 - 1.1e-64 216.4 7.6 1.2e-64 216.2 5.2 1.0 1 0 0 1 1 1 1 G10 protein GDPD PF03009.12 EIW76202.1 - 8.2e-32 110.6 0.0 1.1e-31 110.2 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EIW76202.1 - 0.00011 22.2 0.2 0.00055 20.0 0.1 2.3 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Acyltransferase PF01553.16 EIW76203.1 - 8.6e-33 112.5 0.0 1.2e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase EVE PF01878.13 EIW76204.1 - 1.6e-42 144.8 0.0 2.6e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 EVE domain Band_7 PF01145.20 EIW76205.1 - 4.2e-22 78.9 6.0 6.4e-22 78.3 4.2 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family RRM_1 PF00076.17 EIW76206.1 - 5.7e-33 112.3 0.0 3e-16 58.8 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW76206.1 - 5.3e-20 71.1 0.0 4.5e-11 42.5 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW76206.1 - 1.1e-14 54.0 0.0 3.3e-10 39.6 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIW76206.1 - 3.9e-06 26.6 0.1 1.8e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 EIW76206.1 - 0.00023 20.8 0.0 0.00086 19.0 0.0 2.0 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Pantoate_transf PF02548.10 EIW76206.1 - 0.019 14.1 0.0 0.2 10.7 0.0 2.2 2 0 0 2 2 2 0 Ketopantoate hydroxymethyltransferase RasGAP PF00616.14 EIW76207.1 - 1.1e-32 113.3 0.0 2.6e-32 112.0 0.0 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 EIW76207.1 - 3.6e-08 33.4 0.1 1.2e-07 31.7 0.1 1.9 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain MOR2-PAG1_C PF14225.1 EIW76207.1 - 1.1e-05 25.3 0.5 3.5e-05 23.6 0.1 2.2 2 0 0 2 2 2 1 Cell morphogenesis C-terminal HEAT PF02985.17 EIW76207.1 - 0.0035 17.2 0.5 0.99 9.6 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat Rho_GDI PF02115.12 EIW76207.1 - 0.16 11.3 0.0 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 RHO protein GDP dissociation inhibitor DUF2353 PF09789.4 EIW76208.1 - 0.0011 18.2 21.8 0.021 14.0 5.3 3.0 2 1 1 3 3 3 2 Uncharacterized coiled-coil protein (DUF2353) Gp-FAR-1 PF05823.7 EIW76208.1 - 0.13 12.2 3.3 0.32 10.9 2.3 1.6 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) MscS_porin PF12795.2 EIW76208.1 - 0.42 9.8 34.0 0.47 9.7 13.9 3.1 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain Bacillus_HBL PF05791.6 EIW76208.1 - 1.3 8.4 5.7 51 3.1 4.0 2.5 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DivIC PF04977.10 EIW76208.1 - 2.5 7.6 18.3 1.8 8.1 4.1 3.5 2 1 1 4 4 4 0 Septum formation initiator SRR1 PF07985.7 EIW76209.1 - 0.1 12.5 0.3 0.17 11.8 0.2 1.3 1 0 0 1 1 1 0 SRR1 adh_short PF00106.20 EIW76210.1 - 1.2e-22 80.5 0.0 5.2e-22 78.5 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW76210.1 - 9.9e-16 58.2 0.4 1.9e-15 57.3 0.3 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW76210.1 - 3.3e-09 36.6 0.1 6.3e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 KR domain Pyr_redox PF00070.22 EIW76210.1 - 0.00097 19.4 1.3 0.012 16.0 0.4 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EIW76210.1 - 0.0085 15.7 0.3 0.018 14.7 0.2 1.6 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EIW76210.1 - 0.0092 15.4 0.2 0.04 13.3 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EIW76210.1 - 0.016 14.3 0.0 0.03 13.4 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) YjeF_N PF03853.10 EIW76210.1 - 0.038 13.5 0.1 0.25 10.9 0.1 2.0 2 0 0 2 2 2 0 YjeF-related protein N-terminus Glyco_tran_WecB PF03808.8 EIW76210.1 - 0.054 12.9 0.1 0.47 9.8 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family HTH_29 PF13551.1 EIW76210.1 - 0.085 13.0 0.1 1.2 9.2 0.0 2.7 3 1 0 3 3 3 0 Winged helix-turn helix FAD_binding_3 PF01494.14 EIW76211.1 - 1.3e-08 34.2 0.0 1.6e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SE PF08491.5 EIW76211.1 - 0.00021 20.2 0.0 0.00025 19.9 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Fungal_trans PF04082.13 EIW76212.1 - 5.3e-08 32.0 0.2 1.1e-07 31.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW76212.1 - 1e-05 25.3 6.5 2e-05 24.4 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tautomerase_3 PF14832.1 EIW76213.1 - 3e-08 33.7 0.0 5.7e-08 32.8 0.0 1.5 1 1 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Med26 PF08711.6 EIW76213.1 - 0.015 14.8 0.1 0.026 14.0 0.1 1.5 1 0 0 1 1 1 0 TFIIS helical bundle-like domain Tautomerase PF01361.16 EIW76213.1 - 0.14 11.7 0.0 0.35 10.5 0.0 1.6 2 0 0 2 2 2 0 Tautomerase enzyme TFIID-18kDa PF02269.11 EIW76214.1 - 6.3e-32 109.2 0.1 1.4e-31 108.1 0.1 1.5 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit LptC PF06835.8 EIW76214.1 - 0.58 9.5 2.3 0.57 9.5 0.2 1.8 2 0 0 2 2 2 0 Lipopolysaccharide-assembly, LptC-related PAPS_reduct PF01507.14 EIW76215.1 - 2.5e-40 138.1 0.0 3.6e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Ribonucleas_3_3 PF14622.1 EIW76216.1 - 9.4e-18 64.4 0.0 1.3e-17 63.9 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EIW76216.1 - 7.5e-13 48.9 0.0 1.7e-12 47.7 0.0 1.6 1 1 0 1 1 1 1 Ribonuclease III domain dsrm PF00035.20 EIW76216.1 - 2.2e-06 28.1 0.0 3.7e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Coiled-coil_56 PF09813.4 EIW76217.1 - 0.001 19.0 0.0 0.0018 18.2 0.0 1.4 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 56 DUF3918 PF13056.1 EIW76217.1 - 0.08 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) COX7a PF02238.10 EIW76218.1 - 0.035 13.8 0.9 0.084 12.6 0.6 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase subunit VIIa YEATS PF03366.11 EIW76219.1 - 1.5e-33 114.3 0.1 2.3e-33 113.7 0.1 1.3 1 0 0 1 1 1 1 YEATS family DUF919 PF06034.6 EIW76219.1 - 0.17 11.5 7.3 0.33 10.6 5.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) PI3_PI4_kinase PF00454.22 EIW76220.1 - 3.5e-49 167.3 0.0 7.5e-49 166.3 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EIW76220.1 - 2.1e-35 122.3 0.5 4.1e-35 121.4 0.3 1.5 1 0 0 1 1 1 1 FAT domain UME PF08064.8 EIW76220.1 - 3.3e-21 75.2 0.0 3.4e-20 71.9 0.0 2.7 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.15 EIW76220.1 - 5.9e-12 44.8 0.1 1.5e-11 43.5 0.1 1.8 1 0 0 1 1 1 1 FATC domain DUF3385 PF11865.3 EIW76220.1 - 0.004 17.0 0.0 0.021 14.7 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3385) TPR_19 PF14559.1 EIW76220.1 - 0.011 16.0 0.2 0.19 12.0 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIW76220.1 - 0.024 14.2 0.0 24 4.6 0.0 3.8 3 0 0 3 3 3 0 TPR repeat HEAT PF02985.17 EIW76220.1 - 0.026 14.5 0.5 2.7 8.3 0.0 4.3 3 0 0 3 3 3 0 HEAT repeat TPR_14 PF13428.1 EIW76220.1 - 0.043 14.4 3.0 16 6.4 0.0 5.3 4 1 1 5 5 5 0 Tetratricopeptide repeat HEAT_EZ PF13513.1 EIW76220.1 - 0.082 13.4 1.1 2.4 8.7 0.0 3.9 3 0 0 3 3 3 0 HEAT-like repeat Nop14 PF04147.7 EIW76222.1 - 3.7e-253 842.2 18.6 4.5e-253 842.0 12.9 1.0 1 0 0 1 1 1 1 Nop14-like family GATA PF00320.22 EIW76224.1 - 5.7e-09 35.1 4.3 9.6e-09 34.4 2.9 1.4 1 0 0 1 1 1 1 GATA zinc finger ArfGap PF01412.13 EIW76224.1 - 0.091 12.5 0.1 0.2 11.4 0.1 1.5 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf HCV_NS5a_1a PF08300.8 EIW76226.1 - 1.2 9.0 4.7 1.3 9.0 1.6 2.2 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a zinc finger domain CUE PF02845.11 EIW76228.1 - 4.2e-06 26.1 0.0 6.6e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 CUE domain Rhomboid PF01694.17 EIW76228.1 - 0.0011 19.0 11.9 0.0019 18.2 8.2 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.5 EIW76228.1 - 0.04 14.2 0.2 0.1 12.9 0.1 1.7 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) eIF-3_zeta PF05091.7 EIW76229.1 - 1.6e-181 604.4 0.0 2.2e-181 604.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RRM_1 PF00076.17 EIW76230.1 - 2.1e-18 65.6 1.0 3.1e-18 65.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW76230.1 - 3e-11 43.1 0.0 6.1e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW76230.1 - 3.2e-08 33.2 0.0 5.7e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SDA1 PF05285.7 EIW76230.1 - 0.00023 20.5 13.8 0.00033 20.0 9.6 1.2 1 0 0 1 1 1 1 SDA1 CDC73 PF05179.9 EIW76230.1 - 0.35 10.1 5.3 0.6 9.4 3.6 1.3 1 0 0 1 1 1 0 RNA pol II accessory factor, Cdc73 family UPF0560 PF10577.4 EIW76230.1 - 0.46 8.6 7.3 0.78 7.9 5.1 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 MIP-T3 PF10243.4 EIW76230.1 - 2.6 6.4 27.5 3.8 5.8 19.0 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RR_TM4-6 PF06459.7 EIW76230.1 - 4.9 6.9 12.6 8.4 6.1 8.7 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tautomerase_3 PF14832.1 EIW76233.1 - 1e-08 35.2 0.0 1.3e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.16 EIW76233.1 - 0.026 14.1 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 Tautomerase enzyme RTA1 PF04479.8 EIW76234.1 - 4.5e-31 108.0 2.8 4.5e-31 108.0 2.0 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF3995 PF13160.1 EIW76234.1 - 0.02 14.9 4.2 0.058 13.4 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) DUF4131 PF13567.1 EIW76234.1 - 5 6.5 16.7 0.55 9.6 4.5 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) 4HBT PF03061.17 EIW76235.1 - 0.00028 20.9 0.2 0.00047 20.2 0.1 1.3 1 0 0 1 1 1 1 Thioesterase superfamily HA2 PF04408.18 EIW76236.1 - 8.1e-22 77.1 0.2 1.6e-21 76.2 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EIW76236.1 - 3.2e-13 49.3 0.0 8.5e-13 47.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EIW76236.1 - 5e-12 45.6 0.0 1.1e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EIW76236.1 - 6.6e-05 22.4 0.0 0.00019 20.9 0.0 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EIW76236.1 - 9e-05 22.6 0.1 0.00064 19.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_19 PF13245.1 EIW76236.1 - 0.0085 15.8 2.0 0.01 15.5 0.2 2.0 2 0 0 2 2 2 1 Part of AAA domain ABC_tran PF00005.22 EIW76236.1 - 0.013 15.8 0.9 1.4 9.1 0.1 2.7 2 1 1 3 3 2 0 ABC transporter KaiC PF06745.8 EIW76236.1 - 0.031 13.3 0.1 0.12 11.5 0.0 1.9 2 0 0 2 2 2 0 KaiC T2SE PF00437.15 EIW76236.1 - 0.034 13.0 0.1 0.071 11.9 0.1 1.5 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 EIW76236.1 - 0.038 13.5 0.0 0.09 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.11 EIW76236.1 - 0.067 12.4 0.0 0.27 10.4 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein DUF1355 PF07090.6 EIW76236.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1355) AAA_25 PF13481.1 EIW76236.1 - 0.099 12.0 0.0 0.26 10.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 EIW76236.1 - 0.1 12.3 0.0 0.43 10.3 0.0 2.1 2 0 0 2 2 2 0 Flavivirus DEAD domain Arch_ATPase PF01637.13 EIW76236.1 - 0.16 11.6 0.0 4.5 6.9 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase 4HBT PF03061.17 EIW76237.1 - 6.7e-07 29.3 0.0 1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily STE3 PF02076.10 EIW76238.1 - 5.8e-34 117.4 0.5 6.8e-34 117.2 0.3 1.0 1 0 0 1 1 1 1 Pheromone A receptor DUF368 PF04018.8 EIW76238.1 - 0.058 12.5 1.5 0.28 10.3 1.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF368) STE3 PF02076.10 EIW76239.1 - 7.2e-23 81.0 6.2 8.6e-23 80.8 4.3 1.1 1 0 0 1 1 1 1 Pheromone A receptor DUF898 PF05987.8 EIW76239.1 - 0.11 11.4 3.2 0.11 11.3 1.7 1.3 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Dispanin PF04505.7 EIW76239.1 - 0.55 9.8 3.8 0.33 10.5 0.1 2.2 2 0 0 2 2 2 0 Interferon-induced transmembrane protein His_Phos_1 PF00300.17 EIW76240.1 - 3.4e-18 66.2 0.1 4.4e-18 65.8 0.1 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) SAP18 PF06487.7 EIW76241.1 - 2.6e-27 95.0 0.0 3.3e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Glyco_transf_52 PF07922.6 EIW76241.1 - 0.0086 15.1 0.0 0.012 14.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 52 Cu_amine_oxid PF01179.15 EIW76242.1 - 9.8e-95 317.6 0.0 1.3e-94 317.2 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 EIW76242.1 - 1.8e-07 30.9 0.0 9.4e-07 28.6 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 EIW76242.1 - 0.033 14.2 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 Copper amine oxidase, N2 domain Sugar_tr PF00083.19 EIW76243.1 - 3e-74 250.2 25.5 3.6e-74 249.9 17.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW76243.1 - 1.6e-26 92.8 28.6 1.6e-26 92.8 19.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EIW76243.1 - 2.5e-09 35.9 4.2 2.5e-09 35.9 2.9 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EIW76243.1 - 5.5e-05 21.7 5.9 5.5e-05 21.7 4.1 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein Ribosomal_S5_C PF03719.10 EIW76243.1 - 0.14 11.4 0.0 0.31 10.3 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S5, C-terminal domain Tetraspannin PF00335.15 EIW76243.1 - 0.16 11.2 8.1 0.068 12.4 2.1 2.4 3 0 0 3 3 3 0 Tetraspanin family ubiquitin PF00240.18 EIW76244.1 - 1.9e-24 84.8 0.1 2.1e-24 84.7 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EIW76244.1 - 7.3e-15 54.4 0.2 8e-15 54.2 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EIW76244.1 - 8.4e-05 22.7 0.0 0.00015 21.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin-like domain 2OG-FeII_Oxy_2 PF13532.1 EIW76245.1 - 8.1e-13 48.6 0.0 3.4e-12 46.6 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIW76245.1 - 7.8e-05 22.9 0.0 0.00031 20.9 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1768 PF08719.6 EIW76246.1 - 2.5e-21 76.0 0.0 3.4e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) PI-PLC-X PF00388.14 EIW76246.1 - 0.27 10.6 0.0 0.45 9.9 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain RRM_3 PF08777.6 EIW76247.1 - 7.7e-07 28.9 0.1 7.9e-06 25.6 0.0 2.3 1 1 0 1 1 1 1 RNA binding motif RRM_6 PF14259.1 EIW76247.1 - 0.00022 21.1 0.0 0.39 10.7 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ATG22 PF11700.3 EIW76248.1 - 2.2e-101 339.7 19.1 2.5e-101 339.5 13.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EIW76248.1 - 1.4e-15 56.9 28.6 4.1e-09 35.6 6.3 3.1 2 1 1 3 3 3 3 Major Facilitator Superfamily SHOCT PF09851.4 EIW76248.1 - 0.16 11.4 0.1 0.28 10.7 0.1 1.3 1 0 0 1 1 1 0 Short C-terminal domain Pyr_redox_2 PF07992.9 EIW76249.1 - 8.4e-09 35.6 0.1 9.9e-08 32.0 0.1 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIW76249.1 - 0.0013 18.5 0.3 0.33 10.7 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EIW76249.1 - 0.0073 16.3 0.2 1.1 9.3 0.0 2.5 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW76249.1 - 0.036 13.1 0.1 0.055 12.5 0.1 1.2 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.1 EIW76249.1 - 0.075 11.9 0.0 0.32 9.8 0.0 2.0 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Malic_M PF03949.10 EIW76249.1 - 0.079 12.4 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain DAO PF01266.19 EIW76249.1 - 0.23 10.2 1.0 4.4 6.1 0.2 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase AceK PF06315.6 EIW76249.1 - 0.26 9.5 0.2 0.4 8.9 0.1 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) GST_N_3 PF13417.1 EIW76250.1 - 3.5e-14 52.7 0.1 7.9e-14 51.6 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW76250.1 - 9e-10 38.4 0.0 1.7e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW76250.1 - 1.2e-05 25.0 0.0 2.3e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW76250.1 - 0.0003 21.2 0.0 0.00048 20.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW76250.1 - 0.0072 16.4 0.0 0.026 14.6 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW76250.1 - 0.0077 16.1 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain WD40 PF00400.27 EIW76251.1 - 1.1e-42 142.4 7.7 7.4e-08 31.9 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EIW76251.1 - 0.0026 16.1 0.0 0.023 12.9 0.0 2.1 2 0 0 2 2 2 1 Cytochrome D1 heme domain Lactonase PF10282.4 EIW76251.1 - 0.081 11.9 0.0 0.16 11.0 0.0 1.5 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller PQQ_3 PF13570.1 EIW76251.1 - 0.59 10.4 3.2 1.9 8.8 0.0 3.3 4 0 0 4 4 4 0 PQQ-like domain IncA PF04156.9 EIW76252.1 - 3.8e-05 23.3 2.3 3.8e-05 23.3 1.6 2.1 3 0 0 3 3 3 1 IncA protein Mei4 PF13971.1 EIW76252.1 - 0.022 13.7 0.5 0.036 13.0 0.3 1.3 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 Macoilin PF09726.4 EIW76252.1 - 0.058 11.6 6.8 0.093 10.9 4.7 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF4337 PF14235.1 EIW76252.1 - 1.8 8.4 3.8 4.9 6.9 2.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3373 PF11853.3 EIW76252.1 - 2.4 6.5 3.0 4.5 5.6 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) FlxA PF14282.1 EIW76252.1 - 4.5 7.2 11.5 0.52 10.2 4.4 2.1 2 0 0 2 2 2 0 FlxA-like protein DUF4407 PF14362.1 EIW76252.1 - 6.6 5.5 7.6 17 4.2 5.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) APH PF01636.18 EIW76253.1 - 1.6e-06 28.0 0.0 2.7e-05 24.0 0.0 2.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EIW76253.1 - 0.00032 19.4 0.0 0.046 12.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) RRM_1 PF00076.17 EIW76254.1 - 6.5e-11 41.7 0.0 1.1e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW76254.1 - 1e-09 38.2 0.0 1.7e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIW76254.1 - 0.022 14.5 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 EIW76254.1 - 0.042 13.6 0.0 0.069 13.0 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ofd1_CTDD PF10637.4 EIW76255.1 - 1e-83 280.5 0.0 2.1e-78 263.1 0.0 2.4 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EIW76255.1 - 3.2e-15 56.4 0.0 1.5e-14 54.3 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily SDA1 PF05285.7 EIW76255.1 - 0.038 13.2 19.4 0.011 15.0 10.6 2.0 2 0 0 2 2 2 0 SDA1 BUD22 PF09073.5 EIW76255.1 - 2.2 7.2 18.3 0.28 10.2 8.3 2.1 2 0 0 2 2 2 0 BUD22 CDC14 PF08045.6 EIW76256.1 - 2.9e-36 124.9 0.0 6.2e-33 114.0 0.0 2.2 2 0 0 2 2 2 2 Cell division control protein 14, SIN component RYDR_ITPR PF01365.16 EIW76256.1 - 0.023 13.9 0.0 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 RIH domain Aldedh PF00171.17 EIW76257.1 - 9.1e-145 482.5 2.1 1.2e-144 482.1 1.4 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1870 PF08965.5 EIW76257.1 - 0.019 14.5 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) RWD PF05773.17 EIW76258.1 - 1.9e-06 27.7 0.0 3.3e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 RWD domain SH3_9 PF14604.1 EIW76259.1 - 6e-14 51.3 0.0 1.3e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SAM_2 PF07647.12 EIW76259.1 - 4.4e-13 48.8 0.0 7.6e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_1 PF00018.23 EIW76259.1 - 6.4e-13 47.8 0.2 1.2e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 EIW76259.1 - 1.6e-11 44.3 0.0 3.7e-11 43.1 0.0 1.7 1 0 0 1 1 1 1 PH domain SAM_1 PF00536.25 EIW76259.1 - 7.2e-11 42.1 0.2 1.6e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 EIW76259.1 - 3e-09 36.2 0.0 5.4e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ste50p-SAM PF09235.5 EIW76259.1 - 0.023 14.7 0.2 0.045 13.7 0.1 1.4 1 0 0 1 1 1 0 Ste50p, sterile alpha motif CH PF00307.26 EIW76259.1 - 0.029 14.4 0.0 0.054 13.5 0.0 1.4 1 0 0 1 1 1 0 Calponin homology (CH) domain PH_11 PF15413.1 EIW76259.1 - 0.096 12.9 0.2 0.29 11.4 0.1 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain Ham1p_like PF01725.11 EIW76260.1 - 5.8e-38 130.1 0.0 7.2e-38 129.8 0.0 1.1 1 0 0 1 1 1 1 Ham1 family 4HBT PF03061.17 EIW76261.1 - 1.2e-08 34.9 0.1 2.3e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EIW76261.1 - 2.3e-06 27.5 0.0 2.5e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily AfsA PF03756.8 EIW76261.1 - 0.078 12.6 0.0 0.25 11.0 0.0 1.7 2 0 0 2 2 2 0 A-factor biosynthesis hotdog domain TPR_11 PF13414.1 EIW76262.1 - 5.7e-15 54.7 3.8 1.7e-08 33.9 0.0 5.1 3 1 2 5 5 5 2 TPR repeat TPR_2 PF07719.12 EIW76262.1 - 1.3e-10 40.3 4.7 0.0017 18.1 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIW76262.1 - 3.6e-10 38.9 0.1 0.0021 17.5 0.0 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIW76262.1 - 4.5e-10 39.3 2.8 0.0041 17.0 0.0 5.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIW76262.1 - 4.6e-10 38.8 0.1 0.043 14.0 0.0 4.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIW76262.1 - 2.9e-07 30.9 0.1 6.4e-05 23.5 0.0 7.8 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.1 EIW76262.1 - 1.1e-06 28.3 0.1 5.1e-05 23.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIW76262.1 - 0.00022 20.7 0.3 1.6 8.6 0.0 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIW76262.1 - 0.00042 20.6 20.3 0.075 13.7 0.0 8.1 6 3 3 9 9 8 2 Tetratricopeptide repeat TPR_10 PF13374.1 EIW76262.1 - 0.006 16.4 12.6 0.023 14.6 0.0 5.8 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIW76262.1 - 0.0083 15.8 10.2 0.44 10.4 0.0 7.0 7 2 2 9 9 9 1 Tetratricopeptide repeat ChAPs PF09295.5 EIW76262.1 - 0.16 10.6 0.0 0.4 9.4 0.0 1.5 1 1 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Rab5ip PF07019.7 EIW76264.1 - 1.3e-14 54.0 2.7 1.7e-14 53.6 1.8 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) SMC_N PF02463.14 EIW76265.1 - 6.7e-21 74.5 0.0 1.8e-20 73.1 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EIW76265.1 - 1.4e-18 67.9 0.0 1.4e-18 67.9 0.0 5.5 2 2 1 4 4 4 1 AAA domain AAA_29 PF13555.1 EIW76265.1 - 0.00038 19.9 0.1 0.016 14.6 0.0 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EIW76265.1 - 0.0078 16.2 0.1 0.0078 16.2 0.1 3.1 4 0 0 4 4 4 1 AAA domain AAA PF00004.24 EIW76265.1 - 0.015 15.4 6.4 0.17 12.0 0.1 3.8 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.1 EIW76265.1 - 0.17 10.3 0.0 0.17 10.3 0.0 5.7 3 2 2 5 5 5 0 AAA domain Ribosomal_L13 PF00572.13 EIW76266.1 - 6e-40 136.2 0.1 8.1e-40 135.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 MoCF_biosynth PF00994.19 EIW76267.1 - 1.4e-57 193.1 0.2 2.4e-29 101.6 0.0 2.3 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 EIW76267.1 - 1.5e-29 102.4 0.3 2.4e-29 101.7 0.2 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 EIW76267.1 - 8.5e-16 57.6 0.0 1.8e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) T2SE PF00437.15 EIW76267.1 - 0.032 13.1 0.0 0.099 11.5 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein Peptidase_S10 PF00450.17 EIW76268.1 - 2.3e-98 330.0 0.0 3e-98 329.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF1956 PF09209.6 EIW76268.1 - 0.21 11.5 0.0 23 4.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1956) 14-3-3 PF00244.15 EIW76271.1 - 1.9e-118 393.6 6.4 2.2e-118 393.5 4.4 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 EIW76271.1 - 0.037 13.5 4.1 1.1 8.8 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF837) TPR_19 PF14559.1 EIW76271.1 - 0.15 12.4 1.1 2.3 8.6 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF885 PF05960.6 EIW76271.1 - 0.16 11.0 2.9 0.086 11.9 0.6 1.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF885) HisKA PF00512.20 EIW76271.1 - 0.18 11.8 1.1 2.4 8.2 0.1 2.7 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain DUF1539 PF07560.6 EIW76271.1 - 0.25 11.2 1.9 0.61 9.9 0.2 2.4 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1539) DUF4610 PF15384.1 EIW76272.1 - 0.013 15.0 0.1 0.019 14.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4610) NAD_binding_10 PF13460.1 EIW76273.1 - 1.1e-15 58.0 0.1 1.4e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EIW76273.1 - 8.4e-10 38.2 0.9 1.4e-09 37.5 0.6 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EIW76273.1 - 4.8e-09 36.0 0.0 1.2e-07 31.4 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIW76273.1 - 1.9e-05 23.5 0.1 0.00061 18.5 0.1 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EIW76273.1 - 3.5e-05 22.9 0.5 4.8e-05 22.4 0.3 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 EIW76273.1 - 0.00065 19.6 0.7 0.0011 18.8 0.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.13 EIW76273.1 - 0.00069 19.6 0.1 0.0011 18.9 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain RmlD_sub_bind PF04321.12 EIW76273.1 - 0.00074 18.4 0.0 0.1 11.4 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain NAD_binding_2 PF03446.10 EIW76273.1 - 0.0024 17.7 0.0 0.004 17.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EIW76273.1 - 0.0034 17.4 0.1 0.0062 16.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.7 EIW76273.1 - 0.0044 15.9 0.3 0.39 9.5 0.1 2.3 1 1 1 2 2 2 1 Male sterility protein UDPG_MGDP_dh_N PF03721.9 EIW76273.1 - 0.0055 16.1 0.1 0.0088 15.4 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 EIW76273.1 - 0.016 15.6 0.0 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 EIW76273.1 - 0.038 14.2 0.1 0.06 13.6 0.1 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 EIW76273.1 - 0.064 12.9 0.1 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 KR domain AlaDh_PNT_C PF01262.16 EIW76273.1 - 0.11 12.0 0.3 0.22 11.0 0.2 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Rossmann-like PF10727.4 EIW76273.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Rossmann-like domain DapB_N PF01113.15 EIW76273.1 - 0.16 11.8 0.4 0.28 11.0 0.3 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus WD40 PF00400.27 EIW76274.1 - 9.3e-20 69.7 19.2 1.3e-06 28.0 0.0 8.8 9 1 0 9 9 9 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW76274.1 - 2.6e-14 53.2 4.4 8.6e-08 31.9 0.6 3.8 2 2 2 4 4 4 3 PQQ-like domain PD40 PF07676.7 EIW76274.1 - 5.4e-07 29.1 0.7 0.82 9.4 0.0 5.8 7 0 0 7 7 7 2 WD40-like Beta Propeller Repeat Hira PF07569.6 EIW76274.1 - 0.00011 21.5 0.4 0.18 10.9 0.0 4.0 4 1 1 5 5 5 2 TUP1-like enhancer of split PQQ_3 PF13570.1 EIW76274.1 - 0.00025 21.1 1.8 0.83 10.0 0.1 5.0 5 0 0 5 5 5 1 PQQ-like domain Nup160 PF11715.3 EIW76274.1 - 0.0042 15.2 4.2 4.4 5.3 0.0 4.6 3 2 2 5 5 5 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIW76274.1 - 0.0055 15.5 1.7 0.31 9.7 0.0 3.4 2 2 1 3 3 3 1 Nup133 N terminal like PQQ PF01011.16 EIW76274.1 - 0.064 12.8 1.2 83 2.9 0.0 5.4 7 0 0 7 7 7 0 PQQ enzyme repeat Methyltransf_25 PF13649.1 EIW76275.1 - 0.0015 18.8 0.0 0.0067 16.7 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Catalase-rel PF06628.7 EIW76275.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Catalase-related immune-responsive Pro-kuma_activ PF09286.6 EIW76276.1 - 9e-12 45.2 0.1 3.4e-07 30.3 0.0 2.4 1 1 1 2 2 2 2 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIW76276.1 - 5.7e-10 38.8 2.0 1.6e-09 37.2 0.2 2.0 2 0 0 2 2 2 1 Subtilase family WD40 PF00400.27 EIW76277.1 - 3.2e-21 74.3 33.6 1.3e-06 28.0 0.1 10.6 12 0 0 12 12 12 6 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW76277.1 - 2.1e-11 43.7 0.0 5e-06 26.1 0.1 4.4 3 1 1 4 4 4 2 PQQ-like domain Cytochrom_D1 PF02239.11 EIW76277.1 - 7.4e-05 21.2 0.0 0.15 10.3 0.0 3.8 5 0 0 5 5 5 2 Cytochrome D1 heme domain PQQ_3 PF13570.1 EIW76277.1 - 0.0002 21.4 0.9 0.0048 17.1 0.1 3.6 3 0 0 3 3 3 1 PQQ-like domain PD40 PF07676.7 EIW76277.1 - 0.0034 17.0 5.6 3.4 7.4 0.0 5.9 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EIW76277.1 - 0.029 13.4 0.1 2.7 7.0 0.0 3.7 3 2 1 5 5 5 0 Neuroblastoma-amplified sequence, N terminal Hira PF07569.6 EIW76277.1 - 0.039 13.1 0.1 0.62 9.2 0.0 2.8 1 1 1 2 2 2 0 TUP1-like enhancer of split DPPIV_N PF00930.16 EIW76277.1 - 0.069 11.7 0.2 11 4.5 0.0 4.0 4 2 0 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nucleoporin_N PF08801.6 EIW76277.1 - 0.076 11.7 0.5 3.7 6.1 0.1 2.9 2 1 0 2 2 2 0 Nup133 N terminal like DUF3312 PF11768.3 EIW76277.1 - 0.18 10.0 0.1 18 3.3 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3312) PQQ PF01011.16 EIW76277.1 - 0.19 11.3 1.1 39 4.0 0.0 4.0 4 0 0 4 4 4 0 PQQ enzyme repeat Proteasome_A_N PF10584.4 EIW76277.1 - 1.3 8.3 10.6 23 4.3 0.0 5.6 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature CLPTM1 PF05602.7 EIW76278.1 - 2.2e-134 448.5 0.0 2.7e-134 448.1 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 EIW76278.1 - 0.0011 18.4 0.6 0.0026 17.2 0.4 1.6 1 0 0 1 1 1 1 PQ loop repeat 2TM PF13239.1 EIW76278.1 - 4.7 7.3 10.4 0.87 9.6 1.5 2.8 2 1 1 3 3 3 0 2TM domain Aldo_ket_red PF00248.16 EIW76281.1 - 2.3e-38 131.6 0.0 2.8e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_25 PF13649.1 EIW76283.1 - 0.0031 17.8 0.0 0.023 15.0 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Catalase-rel PF06628.7 EIW76283.1 - 0.0067 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive Pro-kuma_activ PF09286.6 EIW76284.1 - 6.9e-37 126.6 0.3 1.6e-36 125.5 0.2 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIW76284.1 - 1.8e-10 40.4 4.0 1.8e-10 40.4 2.8 1.7 2 0 0 2 2 2 1 Subtilase family DUF1529 PF07485.6 EIW76284.1 - 0.036 13.7 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1259) Methyltransf_25 PF13649.1 EIW76285.1 - 0.011 16.1 0.0 0.028 14.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain WD40 PF00400.27 EIW76286.1 - 8.3e-15 54.0 6.1 7.2e-05 22.5 0.0 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW76286.1 - 1.5e-09 37.7 0.9 2.7e-08 33.5 0.2 2.5 2 1 0 2 2 2 1 PQQ-like domain PD40 PF07676.7 EIW76286.1 - 0.00033 20.2 1.0 7.7 6.3 0.0 5.1 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat PQQ PF01011.16 EIW76286.1 - 0.01 15.2 0.0 1.9 8.1 0.0 3.3 3 0 0 3 3 3 0 PQQ enzyme repeat PQQ_3 PF13570.1 EIW76286.1 - 0.012 15.8 2.4 0.14 12.4 0.1 3.4 3 0 0 3 3 3 0 PQQ-like domain Nop10p PF04135.7 EIW76286.1 - 1.2 8.9 4.5 0.35 10.6 0.5 2.0 2 0 0 2 2 2 0 Nucleolar RNA-binding protein, Nop10p family Methyltransf_25 PF13649.1 EIW76287.1 - 0.0095 16.2 0.0 0.023 15.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PGAP1 PF07819.8 EIW76288.1 - 1.6e-50 171.8 0.0 2.2e-50 171.3 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EIW76288.1 - 6.1e-11 42.2 0.0 1.4e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW76288.1 - 5.5e-08 32.9 1.0 5.5e-08 32.9 0.7 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW76288.1 - 0.0078 15.7 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2305 PF10230.4 EIW76288.1 - 0.046 13.1 0.0 0.095 12.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) LCAT PF02450.10 EIW76288.1 - 0.25 10.2 0.0 0.38 9.6 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF2009 PF09418.5 EIW76289.1 - 2.7e-205 682.4 0.0 3.2e-205 682.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.19 EIW76289.1 - 1.1e-05 25.2 5.9 1.9e-05 24.4 4.1 1.4 1 0 0 1 1 1 1 B-box zinc finger zf-HIT PF04438.11 EIW76289.1 - 0.14 11.8 1.8 0.28 10.8 1.3 1.5 1 0 0 1 1 1 0 HIT zinc finger IBR PF01485.16 EIW76289.1 - 0.29 11.0 5.8 0.69 9.8 4.1 1.6 1 0 0 1 1 1 0 IBR domain DUF3661 PF12400.3 EIW76290.1 - 9.7e-39 132.4 2.7 1.3e-38 131.9 1.8 1.2 1 0 0 1 1 1 1 Vaculolar membrane protein DUF605 PF04652.11 EIW76290.1 - 8.2 5.7 11.2 11 5.2 7.8 1.1 1 0 0 1 1 1 0 Vta1 like AAA PF00004.24 EIW76291.1 - 1.3e-56 190.4 0.0 5.8e-40 136.5 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIW76291.1 - 3.4e-12 46.6 0.6 0.00043 20.4 0.1 4.3 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.1 EIW76291.1 - 9e-10 38.8 0.2 0.0035 17.3 0.0 3.3 2 1 1 3 3 3 2 AAA ATPase domain AAA_19 PF13245.1 EIW76291.1 - 2.5e-09 36.7 2.2 0.0014 18.3 0.1 3.1 3 0 0 3 3 2 2 Part of AAA domain AAA_33 PF13671.1 EIW76291.1 - 8.6e-09 35.4 0.0 0.0022 17.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EIW76291.1 - 1.1e-08 35.8 0.0 0.0015 19.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EIW76291.1 - 1.6e-08 34.6 0.1 1.6e-05 24.8 0.1 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EIW76291.1 - 7.7e-08 32.1 0.2 0.0022 17.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EIW76291.1 - 9.4e-08 31.3 0.2 0.0049 15.9 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EIW76291.1 - 1.9e-07 31.0 0.0 0.025 14.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.16 EIW76291.1 - 2.2e-07 30.2 0.1 0.0083 15.3 0.1 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EIW76291.1 - 2.8e-07 30.8 0.1 0.0014 18.9 0.1 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EIW76291.1 - 6e-07 28.5 0.1 0.014 14.1 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 EIW76291.1 - 9.4e-07 28.4 0.2 0.053 12.9 0.0 2.6 3 0 0 3 3 2 2 IstB-like ATP binding protein RNA_helicase PF00910.17 EIW76291.1 - 1.2e-06 28.6 0.0 0.038 14.1 0.0 2.5 2 0 0 2 2 2 2 RNA helicase CDC48_2 PF02933.12 EIW76291.1 - 1.9e-06 27.4 0.1 1.3e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 NACHT PF05729.7 EIW76291.1 - 2e-06 27.5 1.5 0.019 14.6 0.0 3.6 4 0 0 4 4 3 2 NACHT domain Zeta_toxin PF06414.7 EIW76291.1 - 2.6e-06 26.6 0.0 0.011 14.8 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 EIW76291.1 - 6.5e-06 25.6 3.1 0.34 10.3 0.1 4.2 2 2 2 4 4 4 2 AAA domain Sigma54_activat PF00158.21 EIW76291.1 - 7.3e-06 25.5 0.0 0.067 12.6 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.22 EIW76291.1 - 1.1e-05 25.7 0.3 0.017 15.4 0.1 2.4 2 0 0 2 2 2 1 ABC transporter DUF2075 PF09848.4 EIW76291.1 - 1.8e-05 23.8 0.1 0.043 12.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) KaiC PF06745.8 EIW76291.1 - 3.4e-05 23.0 0.3 0.022 13.8 0.1 2.4 2 0 0 2 2 2 1 KaiC NB-ARC PF00931.17 EIW76291.1 - 5e-05 22.2 0.1 0.15 10.9 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain AAA_11 PF13086.1 EIW76291.1 - 5.6e-05 22.8 0.0 0.25 10.8 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_3 PF07726.6 EIW76291.1 - 9.1e-05 22.0 0.0 0.096 12.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EIW76291.1 - 0.00011 21.8 1.2 0.06 12.9 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EIW76291.1 - 0.00021 21.2 0.0 0.72 9.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain UPF0079 PF02367.12 EIW76291.1 - 0.00034 20.2 0.0 0.45 10.1 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 EIW76291.1 - 0.00047 19.4 0.0 0.94 8.6 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein AAA_30 PF13604.1 EIW76291.1 - 0.00057 19.5 0.0 0.36 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 EIW76291.1 - 0.0011 17.8 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 ResIII PF04851.10 EIW76291.1 - 0.0014 18.5 0.3 2.1 8.1 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit KTI12 PF08433.5 EIW76291.1 - 0.0014 17.9 0.0 0.78 8.8 0.0 2.2 2 0 0 2 2 2 1 Chromatin associated protein KTI12 DEAD PF00270.24 EIW76291.1 - 0.0015 18.0 0.5 34 3.8 0.0 4.1 2 2 2 4 4 4 0 DEAD/DEAH box helicase CPT PF07931.7 EIW76291.1 - 0.0017 18.0 0.0 0.17 11.4 0.0 2.5 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein T2SE PF00437.15 EIW76291.1 - 0.002 17.0 0.0 1.7 7.4 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Sigma54_activ_2 PF14532.1 EIW76291.1 - 0.0033 17.4 0.0 5.3 7.0 0.0 3.1 3 0 0 3 3 3 0 Sigma-54 interaction domain Torsin PF06309.6 EIW76291.1 - 0.0092 15.8 0.0 6.4 6.6 0.0 2.4 2 0 0 2 2 2 0 Torsin AAA_10 PF12846.2 EIW76291.1 - 0.02 14.3 0.0 0.32 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain KAP_NTPase PF07693.9 EIW76291.1 - 0.022 13.7 0.0 6.6 5.6 0.0 3.0 3 0 0 3 3 3 0 KAP family P-loop domain Viral_helicase1 PF01443.13 EIW76291.1 - 0.023 14.2 0.0 3.9 6.9 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase CDC48_N PF02359.13 EIW76291.1 - 0.038 13.9 0.0 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain DAP3 PF10236.4 EIW76291.1 - 0.051 12.5 0.1 1.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 cobW PF02492.14 EIW76291.1 - 0.054 12.9 0.1 1.9 7.8 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.4 EIW76291.1 - 0.062 11.9 0.4 2.1 6.8 0.1 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain SKI PF01202.17 EIW76291.1 - 0.078 12.8 0.4 9 6.1 0.0 2.6 2 1 0 2 2 2 0 Shikimate kinase Zot PF05707.7 EIW76291.1 - 0.079 12.4 0.1 12 5.3 0.1 2.7 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) NTPase_1 PF03266.10 EIW76291.1 - 0.11 12.2 1.0 15 5.2 0.0 2.9 3 0 0 3 3 3 0 NTPase AFG1_ATPase PF03969.11 EIW76291.1 - 0.12 11.1 0.0 12 4.5 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase AAA_29 PF13555.1 EIW76291.1 - 0.14 11.7 0.3 5.3 6.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain IPP-2 PF04979.9 EIW76292.1 - 2.3e-12 47.3 1.0 9e-06 25.9 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase inhibitor 2 (IPP-2) DUF1908 PF08926.6 EIW76292.1 - 0.035 12.8 0.4 0.048 12.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) MSP1_C PF07462.6 EIW76292.1 - 0.65 8.3 4.3 0.84 7.9 3.0 1.2 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus THF_DHG_CYH_C PF02882.14 EIW76293.1 - 2e-15 56.2 0.4 1.7e-08 33.7 0.0 2.9 2 1 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EIW76293.1 - 3.1e-13 49.7 0.0 2.2e-06 27.7 0.0 2.3 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain ORMDL PF04061.9 EIW76294.1 - 4.8e-55 184.8 3.7 5.8e-55 184.5 2.6 1.0 1 0 0 1 1 1 1 ORMDL family DUF2404 PF10296.4 EIW76296.1 - 6.4e-05 23.0 0.1 0.00035 20.6 0.0 2.0 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) Uds1 PF15456.1 EIW76297.1 - 5.1e-21 74.9 4.3 5.1e-21 74.9 3.0 5.2 3 2 2 5 5 5 1 Up-regulated During Septation HR1 PF02185.11 EIW76297.1 - 0.0081 15.8 1.9 0.0081 15.8 1.3 6.7 4 3 1 6 6 6 1 Hr1 repeat APG6 PF04111.7 EIW76297.1 - 0.078 12.0 0.1 0.078 12.0 0.0 4.9 4 1 1 5 5 5 0 Autophagy protein Apg6 Shugoshin_N PF07558.6 EIW76297.1 - 0.2 11.3 3.0 0.21 11.3 0.3 2.4 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF3835 PF12927.2 EIW76297.1 - 6.9 7.7 10.1 0.59 11.1 0.3 3.5 5 0 0 5 5 5 0 Domain of unknown function (DUF3835) ABC_tran PF00005.22 EIW76298.1 - 3.1e-46 157.0 0.2 4.9e-25 88.4 0.0 3.7 3 1 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EIW76298.1 - 3e-20 73.3 0.1 3.1e-06 27.3 0.0 4.2 4 0 0 4 4 4 3 AAA domain SMC_N PF02463.14 EIW76298.1 - 3.2e-11 42.8 3.8 0.004 16.4 0.0 4.4 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_tran_2 PF12848.2 EIW76298.1 - 2.8e-07 30.2 3.1 2.8e-07 30.2 2.1 3.1 3 0 0 3 3 3 1 ABC transporter AAA_29 PF13555.1 EIW76298.1 - 5.3e-07 29.0 0.0 0.0013 18.1 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EIW76298.1 - 1.3e-05 24.4 0.0 0.11 11.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EIW76298.1 - 2.4e-05 24.7 8.0 0.0013 19.0 0.0 3.9 3 1 0 3 3 2 1 AAA domain NACHT PF05729.7 EIW76298.1 - 0.00011 21.9 0.0 0.7 9.5 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA PF00004.24 EIW76298.1 - 0.0002 21.5 0.4 0.63 10.2 0.2 3.8 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EIW76298.1 - 0.00027 20.5 0.4 1 8.7 0.0 3.3 3 0 0 3 3 3 2 AAA-like domain AAA_22 PF13401.1 EIW76298.1 - 0.00027 21.1 7.0 0.69 10.0 0.2 4.4 3 2 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 EIW76298.1 - 0.00027 20.1 0.1 0.44 9.6 0.0 2.8 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EIW76298.1 - 0.00042 19.7 0.1 1.3 8.4 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EIW76298.1 - 0.00055 19.6 2.7 8.6 6.0 0.0 4.5 3 1 1 4 4 4 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EIW76298.1 - 0.00072 19.6 0.0 0.8 9.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase AAA_15 PF13175.1 EIW76298.1 - 0.00098 18.2 0.4 0.25 10.3 0.0 3.4 3 1 0 4 4 4 1 AAA ATPase domain SbcCD_C PF13558.1 EIW76298.1 - 0.0013 18.5 0.5 0.74 9.7 0.1 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 EIW76298.1 - 0.0021 18.0 0.9 1 9.3 0.0 3.3 3 1 0 3 3 2 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EIW76298.1 - 0.0033 17.1 0.5 0.34 10.5 0.0 3.6 4 1 0 4 4 4 1 Archaeal ATPase AAA_33 PF13671.1 EIW76298.1 - 0.0034 17.2 0.2 0.72 9.7 0.0 2.9 2 1 0 2 2 2 1 AAA domain DAP3 PF10236.4 EIW76298.1 - 0.006 15.5 0.0 0.62 8.9 0.0 2.5 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_28 PF13521.1 EIW76298.1 - 0.016 15.2 0.0 0.12 12.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EIW76298.1 - 0.017 14.8 0.2 3.8 7.2 0.0 3.4 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EIW76298.1 - 0.018 14.9 0.0 7.1 6.5 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 EIW76298.1 - 0.029 14.3 10.2 0.11 12.5 0.0 3.5 4 2 0 4 4 2 0 AAA ATPase domain Miro PF08477.8 EIW76298.1 - 0.037 14.5 0.1 4.6 7.7 0.0 3.4 4 0 0 4 4 2 0 Miro-like protein FeoB_N PF02421.13 EIW76298.1 - 0.046 13.0 2.4 0.65 9.2 0.1 3.2 3 0 0 3 3 3 0 Ferrous iron transport protein B AAA_17 PF13207.1 EIW76298.1 - 0.051 14.4 0.5 17 6.2 0.0 3.2 3 1 0 3 3 2 0 AAA domain Med3 PF11593.3 EIW76298.1 - 0.28 10.3 3.8 0.52 9.4 2.6 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Methyltransf_25 PF13649.1 EIW76299.1 - 0.0012 19.1 0.0 0.0033 17.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain WD40 PF00400.27 EIW76300.1 - 2.2e-24 84.3 18.5 2.6e-06 27.0 0.0 9.5 10 0 0 10 10 10 6 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW76300.1 - 3.2e-14 52.9 0.9 9.3e-07 28.5 0.0 4.6 3 3 0 4 4 4 3 PQQ-like domain Nup160 PF11715.3 EIW76300.1 - 8e-06 24.2 3.4 0.069 11.2 0.1 3.3 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIW76300.1 - 1.3e-05 24.1 0.2 0.0011 17.8 0.1 3.4 3 1 0 3 3 3 1 Nup133 N terminal like DUF1513 PF07433.6 EIW76300.1 - 0.00011 21.1 0.0 0.48 9.2 0.0 3.7 2 1 0 3 3 3 2 Protein of unknown function (DUF1513) PD40 PF07676.7 EIW76300.1 - 0.0008 19.0 4.9 1.2e+02 2.5 0.1 7.7 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat Hira PF07569.6 EIW76300.1 - 0.0014 17.9 2.5 0.11 11.6 0.1 3.2 3 1 0 4 4 4 1 TUP1-like enhancer of split Cytochrom_D1 PF02239.11 EIW76300.1 - 0.0016 16.8 0.0 0.011 14.1 0.0 2.2 2 1 0 2 2 2 1 Cytochrome D1 heme domain PQQ_3 PF13570.1 EIW76300.1 - 0.0017 18.5 0.2 1.7 8.9 0.0 4.0 3 0 0 3 3 3 1 PQQ-like domain Coatomer_WDAD PF04053.9 EIW76300.1 - 0.0046 15.7 0.0 0.069 11.9 0.0 2.6 3 0 0 3 3 3 1 Coatomer WD associated region Lactonase PF10282.4 EIW76300.1 - 0.0067 15.5 0.0 0.11 11.6 0.0 2.7 3 0 0 3 3 3 1 Lactonase, 7-bladed beta-propeller PLU-1 PF08429.6 EIW76301.1 - 2.1e-47 161.6 4.0 4.8e-47 160.4 2.8 1.6 1 1 0 1 1 1 1 PLU-1-like protein JmjC PF02373.17 EIW76301.1 - 1.3e-42 144.5 0.7 3.3e-41 140.1 0.2 2.5 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.16 EIW76301.1 - 7.8e-21 73.7 0.0 1.8e-20 72.5 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 EIW76301.1 - 1e-16 60.3 46.5 2.4e-11 43.1 6.7 4.7 4 0 0 4 4 4 3 PHD-finger JmjN PF02375.12 EIW76301.1 - 1.7e-16 59.4 1.8 3.6e-16 58.3 1.2 1.6 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 EIW76301.1 - 2.2e-13 50.0 9.2 2.2e-13 50.0 6.4 2.6 2 0 0 2 2 2 1 C5HC2 zinc finger PHD_2 PF13831.1 EIW76301.1 - 0.0004 19.6 23.0 0.086 12.1 4.8 4.0 3 0 0 3 3 3 3 PHD-finger Prok-RING_1 PF14446.1 EIW76301.1 - 0.0039 16.8 6.7 0.0039 16.8 4.6 4.0 4 0 0 4 4 4 2 Prokaryotic RING finger family 1 zf-RanBP PF00641.13 EIW76301.1 - 7.3 5.7 12.9 5.7 6.1 0.2 3.5 3 0 0 3 3 3 0 Zn-finger in Ran binding protein and others CorA PF01544.13 EIW76302.1 - 2.9e-46 157.8 0.1 3.6e-46 157.5 0.1 1.1 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3826 PF12875.2 EIW76302.1 - 0.0074 16.0 0.5 0.083 12.5 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3826) Baculo_PEP_C PF04513.7 EIW76302.1 - 0.008 15.9 0.7 0.015 15.1 0.2 1.7 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus ACT_4 PF13291.1 EIW76302.1 - 0.11 12.8 0.2 0.39 11.0 0.1 2.0 2 0 0 2 2 2 0 ACT domain PCI PF01399.22 EIW76303.1 - 2.3e-12 47.1 0.0 6.8e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 PCI domain HET PF06985.6 EIW76304.1 - 1.2e-24 87.0 0.2 2.6e-24 85.9 0.1 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box-like PF12937.2 EIW76305.1 - 9.2e-05 22.0 0.2 0.00025 20.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIW76306.1 - 0.00017 21.2 0.0 0.00049 19.7 0.0 1.9 1 1 0 1 1 1 1 F-box-like Pro-kuma_activ PF09286.6 EIW76307.1 - 1.6e-38 131.9 0.0 2.6e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIW76307.1 - 8e-08 31.7 0.5 2.2e-07 30.3 0.0 1.7 1 1 0 2 2 2 1 Subtilase family WD40 PF00400.27 EIW76308.1 - 1.1e-31 107.5 14.1 5e-12 45.2 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EIW76308.1 - 0.00013 20.2 0.0 0.044 11.9 0.0 2.6 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Apc4_WD40 PF12894.2 EIW76308.1 - 0.00066 19.1 0.0 11 5.6 0.0 4.0 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.11 EIW76308.1 - 0.011 14.0 0.0 1 7.5 0.0 2.9 2 1 1 3 3 3 0 Cytochrome D1 heme domain Spc97_Spc98 PF04130.8 EIW76310.1 - 2.2e-54 184.7 0.0 4.5e-54 183.6 0.0 1.5 1 1 0 1 1 1 1 Spc97 / Spc98 family Rhabdo_M1 PF03342.8 EIW76310.1 - 0.085 11.9 0.2 0.18 10.9 0.1 1.4 1 0 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) Mgm101p PF06420.7 EIW76311.1 - 9.1e-91 301.7 0.0 1.5e-90 301.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 F-box-like PF12937.2 EIW76313.1 - 0.00019 21.1 2.0 0.00048 19.8 0.6 2.3 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 EIW76313.1 - 1.4 8.6 4.0 5.6 6.7 0.2 2.6 2 0 0 2 2 2 0 F-box domain vWA-TerF-like PF10138.4 EIW76314.1 - 5.5e-07 29.6 0.0 7.6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 EIW76314.1 - 2e-06 27.6 0.0 8.8e-06 25.5 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EIW76314.1 - 2.5e-05 24.4 0.0 9.9e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain PCI PF01399.22 EIW76315.1 - 7.6e-13 48.6 0.0 2.1e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 PCI domain Thioredoxin_4 PF13462.1 EIW76316.1 - 3.1e-11 43.5 0.0 4.6e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.15 EIW76316.1 - 0.0056 16.2 0.6 0.028 13.9 0.0 2.1 1 1 1 2 2 2 1 DSBA-like thioredoxin domain IU_nuc_hydro PF01156.14 EIW76317.1 - 6.5e-96 321.2 0.1 7.4e-96 321.0 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase FH2 PF02181.18 EIW76318.1 - 1.2e-82 277.7 0.7 3.6e-82 276.2 0.0 2.1 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EIW76318.1 - 2e-25 89.2 0.0 1.4e-18 66.9 0.0 2.8 3 0 0 3 3 3 2 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EIW76318.1 - 1.3e-21 76.9 0.3 3.8e-21 75.4 0.0 2.0 2 0 0 2 2 2 1 Diaphanous FH3 Domain MCM PF00493.18 EIW76319.1 - 1.2e-136 454.9 1.2 1.4e-136 454.6 0.3 1.5 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EIW76319.1 - 2.9e-23 82.6 0.0 6e-23 81.6 0.0 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EIW76319.1 - 1.8e-07 30.5 0.0 1.3e-06 27.7 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EIW76319.1 - 0.0025 17.4 0.0 0.0063 16.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EIW76319.1 - 0.0033 16.9 0.0 0.0071 15.8 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 EIW76319.1 - 0.063 13.0 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Y_phosphatase3 PF13350.1 EIW76320.1 - 8.2e-49 166.0 0.0 1.4e-48 165.2 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EIW76320.1 - 7.7e-14 51.5 0.1 2.2e-13 50.0 0.1 1.8 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EIW76320.1 - 0.0015 17.9 0.0 0.002 17.4 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EIW76320.1 - 0.0022 18.0 0.0 0.0045 17.0 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 EIW76320.1 - 0.032 13.5 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Vac14_Fig4_bd PF11916.3 EIW76321.1 - 2.9e-81 270.9 7.7 4.9e-81 270.2 5.3 1.4 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EIW76321.1 - 1.2e-42 144.2 0.0 2.5e-38 130.3 0.0 3.6 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EIW76321.1 - 9.2e-12 44.0 0.2 0.0012 18.7 0.0 6.4 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EIW76321.1 - 0.00047 20.5 0.0 14 6.3 0.0 5.6 5 0 0 5 5 5 1 HEAT-like repeat Cnd1 PF12717.2 EIW76321.1 - 0.0077 16.0 0.6 1.8 8.3 0.0 3.4 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 EIW76321.1 - 0.053 13.4 0.5 5.5 6.8 0.0 3.3 3 0 0 3 3 3 0 Parkin co-regulated protein STE3 PF02076.10 EIW76322.1 - 1.1e-56 191.9 19.8 1.3e-56 191.7 13.7 1.0 1 0 0 1 1 1 1 Pheromone A receptor STE3 PF02076.10 EIW76323.1 - 1.4e-45 155.5 15.7 3.8e-45 154.1 10.9 1.6 1 1 0 1 1 1 1 Pheromone A receptor PAGK PF15284.1 EIW76323.1 - 0.0059 16.3 0.9 0.77 9.5 0.1 2.7 2 0 0 2 2 2 2 Phage-encoded virulence factor STE3 PF02076.10 EIW76324.1 - 4e-30 104.8 4.3 2.7e-29 102.1 3.0 1.8 1 1 0 1 1 1 1 Pheromone A receptor Myelin_PLP PF01275.14 EIW76324.1 - 0.0028 17.0 0.9 0.0036 16.6 0.6 1.1 1 0 0 1 1 1 1 Myelin proteolipid protein (PLP or lipophilin) Wzy_C PF04932.10 EIW76324.1 - 0.041 13.6 0.7 0.18 11.5 0.0 1.9 1 1 1 2 2 2 0 O-Antigen ligase STE3 PF02076.10 EIW76325.1 - 2.6e-56 190.8 15.6 3.2e-56 190.5 10.8 1.1 1 0 0 1 1 1 1 Pheromone A receptor ELO PF01151.13 EIW76325.1 - 0.66 9.2 8.9 0.2 10.9 2.1 2.5 2 1 1 3 3 3 0 GNS1/SUR4 family Beta_helix PF13229.1 EIW76326.1 - 9e-10 38.5 27.5 7.8e-07 28.9 6.0 3.2 1 1 2 3 3 3 2 Right handed beta helix region NosD PF05048.8 EIW76326.1 - 0.00018 20.7 9.2 0.0096 15.0 6.3 2.5 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Rhodopsin_N PF10413.4 EIW76326.1 - 0.016 14.8 0.0 0.035 13.7 0.0 1.6 1 0 0 1 1 1 0 Amino terminal of the G-protein receptor rhodopsin DUF3042 PF11240.3 EIW76326.1 - 2 8.2 8.6 0.27 11.0 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3042) MFS_1 PF07690.11 EIW76329.1 - 6.3e-24 84.3 47.9 1e-16 60.6 16.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Bacteriocin_IIc PF10439.4 EIW76329.1 - 0.07 13.2 13.4 0.067 13.3 1.3 3.6 2 1 1 3 3 3 0 Bacteriocin class II with double-glycine leader peptide TPR_11 PF13414.1 EIW76331.1 - 0.00041 19.9 4.0 0.11 12.1 0.1 2.6 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 EIW76331.1 - 0.013 15.3 1.4 4.9 7.3 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIW76331.1 - 0.03 13.9 0.2 0.61 9.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.13 EIW76331.1 - 0.031 14.1 0.1 0.5 10.2 0.0 2.2 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Doppel PF11466.3 EIW76333.1 - 0.03 13.8 0.7 0.07 12.7 0.5 1.6 1 0 0 1 1 1 0 Prion-like protein Doppel DUF2628 PF10947.3 EIW76333.1 - 0.087 12.6 3.7 0.15 11.8 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2628) MFS_1 PF07690.11 EIW76335.1 - 2.1e-36 125.3 40.2 6e-36 123.8 27.9 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EIW76335.1 - 6.1e-13 47.8 9.1 1.3e-12 46.7 6.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIW76335.1 - 1.8e-07 30.1 11.8 1.8e-07 30.1 8.2 3.5 3 1 0 4 4 4 2 Sugar (and other) transporter DUF500 PF04366.7 EIW76336.1 - 0.22 10.9 1.1 13 5.2 0.0 3.2 1 1 2 3 3 3 0 Family of unknown function (DUF500) Toxin_39 PF15500.1 EIW76336.1 - 0.99 9.5 8.5 11 6.1 0.1 3.5 1 1 1 3 3 3 0 Putative RNase-like toxin Gla PF00594.15 EIW76336.1 - 2.8 7.7 15.7 52 3.6 0.1 5.9 5 1 4 9 9 9 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Prok-TraM PF09228.5 EIW76336.1 - 6.7 6.9 12.5 29 4.8 0.3 3.6 1 1 2 3 3 3 0 Prokaryotic Transcriptional repressor TraM FAD_binding_4 PF01565.18 EIW76337.1 - 3.7e-31 107.4 3.5 3.7e-31 107.4 2.4 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EIW76337.1 - 2.8e-08 33.5 0.0 7.6e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like P-mevalo_kinase PF04275.9 EIW76337.1 - 0.028 14.1 0.1 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphomevalonate kinase LNS2 PF08235.8 EIW76338.1 - 1.5e-71 239.0 0.0 2.4e-71 238.3 0.0 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EIW76338.1 - 2.7e-32 110.7 0.0 6.6e-32 109.4 0.0 1.7 1 0 0 1 1 1 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 EIW76338.1 - 0.0057 16.0 0.2 0.15 11.4 0.0 2.4 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) MFS_1 PF07690.11 EIW76339.1 - 3.2e-18 65.5 16.8 3.2e-18 65.5 11.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3328 PF11807.3 EIW76340.1 - 6.3e-20 71.7 8.4 1.3e-19 70.7 5.8 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Trypan_PARP PF05887.6 EIW76341.1 - 0.014 15.1 8.2 0.032 14.0 5.7 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Zip PF02535.17 EIW76343.1 - 0.62 9.0 14.6 0.85 8.5 10.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Tachykinin PF02202.11 EIW76345.1 - 0.054 13.1 0.1 0.2 11.4 0.1 2.0 1 0 0 1 1 1 0 Tachykinin family NAD_binding_1 PF00175.16 EIW76346.1 - 1.3e-11 44.9 0.0 1.9e-10 41.2 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Globin PF00042.17 EIW76346.1 - 1.2e-08 35.2 0.0 2e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.19 EIW76346.1 - 1.5e-08 34.6 0.0 2.4e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EIW76346.1 - 0.00093 19.1 0.0 0.016 15.1 0.0 2.5 3 0 0 3 3 3 1 Ferric reductase NAD binding domain Protoglobin PF11563.3 EIW76346.1 - 0.0035 16.9 0.1 0.0079 15.8 0.0 1.6 1 1 0 1 1 1 1 Protoglobin B3 PF02362.16 EIW76346.1 - 0.046 13.3 0.1 0.19 11.3 0.0 2.0 3 0 0 3 3 3 0 B3 DNA binding domain DUF2390 PF09523.5 EIW76346.1 - 0.11 12.6 0.2 0.21 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) Methyltransf_25 PF13649.1 EIW76347.1 - 4.1e-06 27.0 0.0 9.1e-06 25.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TFIIB PF00382.14 EIW76348.1 - 6.7e-36 121.9 0.0 8.9e-21 73.4 0.0 2.3 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EIW76348.1 - 4.1e-13 48.4 1.3 6.8e-13 47.7 0.9 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_28 PF13518.1 EIW76348.1 - 0.0065 16.4 0.0 3.8 7.6 0.0 3.1 3 0 0 3 3 3 1 Helix-turn-helix domain Cyclin_C PF02984.14 EIW76348.1 - 0.034 14.0 0.0 0.21 11.5 0.0 2.0 2 0 0 2 2 2 0 Cyclin, C-terminal domain HTH_23 PF13384.1 EIW76348.1 - 0.044 13.4 0.1 9.2 6.0 0.0 3.1 3 0 0 3 3 3 0 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.1 EIW76348.1 - 0.067 12.3 0.0 18 4.6 0.0 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain of transposase family ISL3 HTH_5 PF01022.15 EIW76348.1 - 0.1 12.2 0.0 3.3 7.4 0.0 2.9 3 0 0 3 3 3 0 Bacterial regulatory protein, arsR family HTH_24 PF13412.1 EIW76348.1 - 0.12 11.7 0.1 2.9 7.3 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding UNC45-central PF11701.3 EIW76348.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central Btz PF09405.5 EIW76349.1 - 1.7e-06 28.1 11.1 1.7e-06 28.1 7.7 2.5 2 1 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding Abhydrolase_6 PF12697.2 EIW76350.1 - 7.6e-38 130.6 0.3 1.4e-37 129.7 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW76350.1 - 4.6e-22 78.7 0.0 8.8e-22 77.7 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW76350.1 - 1.1e-13 51.1 0.0 3.3e-13 49.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EIW76350.1 - 1.8e-07 29.9 0.0 3.3e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Ndr family Abhydrolase_4 PF08386.5 EIW76350.1 - 0.001 18.9 0.0 0.0017 18.1 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 EIW76350.1 - 0.042 13.6 0.0 0.35 10.7 0.0 2.2 2 0 0 2 2 2 0 Putative lysophospholipase Alpha_L_fucos PF01120.12 EIW76353.1 - 4.6e-85 285.5 2.1 6e-85 285.1 1.4 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase WD40 PF00400.27 EIW76354.1 - 4.1e-15 54.9 11.1 0.016 15.0 0.5 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat eIF2A PF08662.6 EIW76354.1 - 0.0001 22.0 0.0 0.35 10.5 0.0 3.3 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EIW76354.1 - 0.00094 18.7 0.0 1.2 8.9 0.0 3.7 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EIW76354.1 - 0.0016 16.3 0.1 0.049 11.4 0.0 2.1 2 0 0 2 2 2 2 IKI3 family tRNA-synt_1d PF00750.14 EIW76354.1 - 0.17 10.6 0.0 0.24 10.1 0.0 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (R) PAP_central PF04928.12 EIW76357.1 - 4.8e-103 343.3 0.0 6.7e-103 342.9 0.0 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EIW76357.1 - 9.2e-45 151.9 0.0 1.5e-44 151.3 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EIW76357.1 - 1.6e-08 34.7 0.0 5.4e-08 33.0 0.0 1.9 2 0 0 2 2 2 1 Nucleotidyltransferase domain Nrap PF03813.9 EIW76357.1 - 0.094 10.2 0.0 0.16 9.4 0.0 1.3 1 0 0 1 1 1 0 Nrap protein GatB_N PF02934.10 EIW76359.1 - 2.8e-107 357.8 0.0 3.6e-107 357.5 0.0 1.1 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EIW76359.1 - 1.2e-31 109.4 0.0 1.8e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 GatB domain RdRP PF05183.7 EIW76361.1 - 4.7e-135 451.5 0.0 7.2e-135 450.9 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRN3 PF05327.6 EIW76362.1 - 3.3e-151 504.1 0.0 6e-151 503.3 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase I specific transcription initiation factor RRN3 GHMP_kinases_C PF08544.8 EIW76362.1 - 0.0019 18.3 0.3 0.0051 16.9 0.0 1.9 2 0 0 2 2 2 1 GHMP kinases C terminal Complex1_LYR PF05347.10 EIW76363.1 - 3.4e-08 33.1 1.0 5.6e-08 32.4 0.7 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EIW76363.1 - 4.6e-07 29.9 1.6 7.5e-07 29.2 1.1 1.4 1 1 0 1 1 1 1 Complex1_LYR-like tRNA-synt_1 PF00133.17 EIW76363.1 - 0.062 11.2 0.0 0.07 11.1 0.0 1.0 1 0 0 1 1 1 0 tRNA synthetases class I (I, L, M and V) vWA-TerF-like PF10138.4 EIW76365.1 - 1.7e-06 28.0 0.0 2.4e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 EIW76365.1 - 1.3e-05 25.4 0.0 2.7e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EIW76365.1 - 0.00045 20.0 0.1 0.23 11.1 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain Pro-kuma_activ PF09286.6 EIW76366.1 - 8.4e-37 126.3 0.2 1.4e-36 125.6 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIW76366.1 - 1.3e-08 34.3 3.7 1.3e-08 34.3 2.6 1.6 1 1 0 2 2 2 1 Subtilase family F-box-like PF12937.2 EIW76368.1 - 4.2e-07 29.5 0.2 9.5e-07 28.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW76368.1 - 0.14 11.8 1.9 1.8 8.2 0.2 2.5 2 0 0 2 2 2 0 F-box domain PAXIP1_C PF15364.1 EIW76370.1 - 0.01 15.7 5.4 0.01 15.7 3.7 3.6 3 1 0 4 4 4 1 PAXIP1-associated-protein-1 C term PTIP binding protein Afi1 PF07792.7 EIW76370.1 - 9.9 6.1 13.4 0.26 11.2 3.8 2.1 1 1 1 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Hep_59 PF07052.6 EIW76372.1 - 4.1e-23 81.7 4.7 4.1e-23 81.7 3.3 2.0 1 1 1 2 2 2 1 Hepatocellular carcinoma-associated antigen 59 DUF382 PF04037.8 EIW76372.1 - 0.63 9.8 4.6 0.55 10.0 1.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF382) Serglycin PF04360.7 EIW76375.1 - 0.012 15.3 3.5 0.081 12.6 0.2 2.6 2 0 0 2 2 2 0 Serglycin DLIC PF05783.6 EIW76376.1 - 1.4e-33 116.3 0.4 4.1e-14 52.1 0.0 5.3 3 1 0 3 3 3 3 Dynein light intermediate chain (DLIC) MMR_HSR1 PF01926.18 EIW76376.1 - 0.0075 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase KTI12 PF08433.5 EIW76376.1 - 0.068 12.3 0.0 0.098 11.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 GTP_EFTU PF00009.22 EIW76376.1 - 0.092 12.1 0.0 4.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EIW76376.1 - 0.1 12.5 0.1 0.4 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Miro PF08477.8 EIW76376.1 - 0.21 12.0 0.0 4 7.9 0.0 2.6 3 1 0 3 3 3 0 Miro-like protein AAA_18 PF13238.1 EIW76376.1 - 0.23 11.7 0.0 0.43 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain TIP41 PF04176.8 EIW76377.1 - 1.2e-47 161.5 0.0 9e-47 158.6 0.0 1.9 1 1 0 1 1 1 1 TIP41-like family DUF2804 PF10974.3 EIW76377.1 - 0.046 12.5 0.0 0.065 12.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2804) Ribosomal_L23eN PF03939.8 EIW76377.1 - 0.074 13.0 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L23, N-terminal domain vWA-TerF-like PF10138.4 EIW76378.1 - 1.3e-06 28.4 0.0 1.8e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 EIW76378.1 - 0.012 15.6 0.0 0.026 14.6 0.0 1.5 1 1 0 1 1 1 0 von Willebrand factor type A domain VWA PF00092.23 EIW76378.1 - 0.016 14.9 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type A domain WD40 PF00400.27 EIW76380.1 - 5.6e-32 108.4 23.2 2.5e-11 43.0 0.0 10.8 13 0 0 13 13 13 6 WD domain, G-beta repeat eIF2A PF08662.6 EIW76380.1 - 1.7e-10 40.9 0.0 0.0068 16.1 0.0 5.6 3 1 3 6 6 6 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EIW76380.1 - 8.7e-10 38.4 4.8 0.0022 17.5 0.1 4.3 2 1 1 3 3 3 2 PQQ-like domain PD40 PF07676.7 EIW76380.1 - 1.8e-06 27.4 3.7 0.94 9.2 0.0 7.5 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat PQQ_3 PF13570.1 EIW76380.1 - 0.019 15.2 1.6 2.1 8.7 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain DPPIV_N PF00930.16 EIW76380.1 - 0.033 12.7 0.0 1.1 7.8 0.0 3.6 3 1 0 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region F-box-like PF12937.2 EIW76381.1 - 1.6e-05 24.5 0.6 7.1e-05 22.4 0.0 2.4 2 1 0 2 2 2 1 F-box-like Macro PF01661.16 EIW76382.1 - 0.029 14.2 0.1 0.067 13.1 0.1 1.6 1 1 0 1 1 1 0 Macro domain Aa_trans PF01490.13 EIW76383.1 - 3.8e-22 78.3 37.1 5e-22 77.9 25.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein UPF0154 PF03672.8 EIW76383.1 - 0.049 13.2 0.4 0.21 11.2 0.3 2.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) NADH_Oxid_Nqo15 PF11497.3 EIW76383.1 - 0.085 12.5 0.0 5.7 6.6 0.0 2.6 2 0 0 2 2 2 0 NADH-quinone oxidoreductase chain 15 DUF2633 PF11119.3 EIW76383.1 - 0.19 11.4 7.6 1.7 8.3 0.5 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2633) IBV_3C PF03620.8 EIW76383.1 - 1.1 9.1 4.9 0.79 9.6 0.2 2.9 2 0 0 2 2 2 0 IBV 3C protein F-box-like PF12937.2 EIW76384.1 - 0.00028 20.5 0.0 0.00062 19.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIW76385.1 - 0.00079 19.1 0.1 0.0022 17.6 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIW76386.1 - 1.8e-07 30.7 0.0 2.2e-06 27.3 0.0 2.9 3 1 0 3 3 3 1 F-box-like LRR_8 PF13855.1 EIW76386.1 - 3.1e-06 26.8 5.9 0.11 12.2 0.0 4.6 2 2 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 EIW76386.1 - 0.00094 18.7 1.2 11 5.7 0.0 4.5 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EIW76387.1 - 0.0018 17.9 0.0 0.0052 16.4 0.0 1.9 1 1 0 1 1 1 1 F-box-like UL11 PF11094.3 EIW76387.1 - 0.12 12.1 0.5 0.28 11.0 0.0 1.9 1 1 1 2 2 2 0 Membrane-associated tegument protein PRA1 PF03208.14 EIW76388.1 - 0.31 10.3 11.8 0.08 12.2 0.7 2.7 2 1 0 2 2 2 0 PRA1 family protein DUF3924 PF13062.1 EIW76390.1 - 0.04 13.7 0.0 8.1 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3924) Trep_Strep PF09605.5 EIW76390.1 - 0.084 12.5 0.8 0.097 12.3 0.5 1.1 1 0 0 1 1 1 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF588 PF04535.7 EIW76390.1 - 0.098 12.2 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF588) HSP20 PF00011.16 EIW76391.1 - 8.3e-19 67.3 0.0 1e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family HSP20 PF00011.16 EIW76392.1 - 1.8e-22 79.0 0.2 2.1e-22 78.8 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EIW76392.1 - 0.014 15.9 0.0 0.02 15.4 0.0 1.3 1 0 0 1 1 1 0 CS domain DUF4097 PF13349.1 EIW76392.1 - 0.072 12.6 0.0 0.1 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) Glt_symporter PF03616.9 EIW76393.1 - 0.013 14.0 5.3 0.022 13.2 3.7 1.3 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF3985 PF13153.1 EIW76393.1 - 0.14 11.9 4.8 0.54 10.1 3.3 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3985) NIF PF03031.13 EIW76395.1 - 8.2e-15 54.8 0.0 1.2e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Peptidase_M24 PF00557.19 EIW76396.1 - 7e-46 156.4 0.0 8.4e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 HET PF06985.6 EIW76397.1 - 7.2e-18 65.0 3.6 2.5e-15 56.8 0.1 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NAD_binding_9 PF13454.1 EIW76397.1 - 0.029 14.1 0.3 0.071 12.8 0.2 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding HSP20 PF00011.16 EIW76398.1 - 4.5e-23 81.0 0.0 5.4e-23 80.7 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EIW76398.1 - 0.0015 19.0 0.0 0.0024 18.3 0.0 1.3 1 0 0 1 1 1 1 CS domain DUF4097 PF13349.1 EIW76398.1 - 0.016 14.7 0.0 0.021 14.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) Arb1 PF09692.5 EIW76399.1 - 0.0014 17.5 0.0 0.0057 15.5 0.0 1.8 2 0 0 2 2 2 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 Cwf_Cwc_15 PF04889.7 EIW76399.1 - 2.6 7.6 10.5 3 7.4 0.0 3.2 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein zf-CCCH PF00642.19 EIW76400.1 - 0.00029 20.4 1.5 0.00052 19.6 1.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EIW76400.1 - 0.69 10.0 5.6 1.4 8.9 3.9 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type TAF4 PF05236.9 EIW76401.1 - 1.3e-27 96.7 11.5 2.8e-18 66.1 0.1 2.6 2 2 0 2 2 2 2 Transcription initiation factor TFIID component TAF4 family TAF PF02969.12 EIW76401.1 - 0.067 13.1 0.0 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) Nup188 PF10487.4 EIW76402.1 - 1.1e-11 43.4 0.0 1.7e-09 36.2 0.0 3.1 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 DUF3414 PF11894.3 EIW76402.1 - 0.01 12.7 0.0 0.027 11.4 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3414) BPD_transp_2 PF02653.11 EIW76403.1 - 0.021 13.8 4.4 0.04 12.8 3.0 1.5 1 1 0 1 1 1 0 Branched-chain amino acid transport system / permease component DUF3377 PF11857.3 EIW76403.1 - 0.053 13.1 1.5 0.054 13.1 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) HSP20 PF00011.16 EIW76405.1 - 1.3e-23 82.7 0.0 1.6e-23 82.5 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EIW76405.1 - 0.037 14.5 0.0 0.13 12.8 0.0 1.8 1 1 1 2 2 2 0 CS domain DUF4097 PF13349.1 EIW76405.1 - 0.049 13.1 0.0 0.067 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) HSP20 PF00011.16 EIW76407.1 - 2.5e-23 81.8 0.0 3e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EIW76407.1 - 0.022 15.3 0.0 0.039 14.5 0.0 1.4 1 1 0 1 1 1 0 CS domain DUF3642 PF12182.3 EIW76407.1 - 0.055 13.8 0.1 0.089 13.2 0.0 1.2 1 0 0 1 1 1 0 Bacterial lipoprotein BON PF04972.12 EIW76407.1 - 0.072 12.8 0.0 2.3 8.0 0.0 2.2 2 0 0 2 2 2 0 BON domain WD40 PF00400.27 EIW76408.1 - 8.6e-123 396.3 41.1 8.3e-13 47.6 0.0 14.2 14 0 0 14 14 14 14 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW76408.1 - 4.5e-11 42.6 5.2 0.0011 18.5 0.1 4.0 2 2 1 3 3 3 3 PQQ-like domain Nup160 PF11715.3 EIW76408.1 - 1e-09 37.1 12.4 0.12 10.4 0.0 7.0 3 3 3 8 8 8 4 Nucleoporin Nup120/160 eIF2A PF08662.6 EIW76408.1 - 4.3e-09 36.3 0.0 0.018 14.7 0.0 4.2 2 2 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EIW76408.1 - 2.2e-07 29.9 6.7 0.19 10.4 0.1 5.8 2 2 1 4 4 4 3 Nup133 N terminal like Nbas_N PF15492.1 EIW76408.1 - 2.6e-07 30.0 10.9 3.3 6.7 0.0 8.0 4 3 4 9 9 9 3 Neuroblastoma-amplified sequence, N terminal PQQ_3 PF13570.1 EIW76408.1 - 8.5e-06 25.8 7.0 4.9 7.5 0.0 7.2 8 0 0 8 8 8 2 PQQ-like domain PD40 PF07676.7 EIW76408.1 - 7.4e-05 22.3 2.8 32 4.3 0.0 6.7 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 EIW76408.1 - 0.021 13.0 0.0 31 2.6 0.0 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3312) IKI3 PF04762.7 EIW76408.1 - 0.14 9.9 0.0 3.2 5.4 0.0 2.8 3 0 0 3 3 3 0 IKI3 family PspC PF04024.7 EIW76410.1 - 1.7 8.1 0.0 1.7 8.1 0.0 3.6 3 1 0 3 3 3 0 PspC domain BRCT PF00533.21 EIW76411.1 - 2.4e-07 30.8 0.0 4.3e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EIW76411.1 - 0.00035 20.3 0.0 0.24 11.2 0.0 2.4 2 0 0 2 2 2 2 twin BRCT domain fn3 PF00041.16 EIW76411.1 - 0.0023 18.0 0.3 0.0069 16.4 0.2 1.8 1 1 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.3 EIW76411.1 - 0.014 15.1 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) Pol_alpha_B_N PF08418.5 EIW76411.1 - 1.3 8.5 10.3 1.4 8.3 6.5 1.6 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal NADH_dehy_S2_C PF06444.6 EIW76413.1 - 0.92 9.8 6.2 1.9 8.8 4.3 1.5 1 0 0 1 1 1 0 NADH dehydrogenase subunit 2 C-terminus Afi1 PF07792.7 EIW76413.1 - 6.9 6.6 8.5 2.1 8.3 1.0 2.6 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Nucleo_P87 PF07267.6 EIW76413.1 - 9.5 4.7 12.9 0.066 11.8 1.6 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 HSP20 PF00011.16 EIW76415.1 - 3.3e-24 84.6 0.1 3.9e-24 84.4 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EIW76415.1 - 0.00038 20.9 0.0 0.00062 20.2 0.0 1.3 1 1 0 1 1 1 1 CS domain DUF4097 PF13349.1 EIW76415.1 - 0.035 13.6 0.1 0.05 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) BON PF04972.12 EIW76415.1 - 0.044 13.5 0.1 1.8 8.3 0.0 2.2 2 0 0 2 2 2 0 BON domain F-box-like PF12937.2 EIW76417.1 - 0.012 15.3 0.2 0.042 13.5 0.2 2.0 1 1 0 1 1 1 0 F-box-like DUF1399 PF07173.7 EIW76418.1 - 1.9e-25 89.7 0.2 3.3e-19 69.5 0.0 3.1 2 1 1 3 3 3 3 Protein of unknown function (DUF1399) UPF0547 PF10571.4 EIW76418.1 - 0.0059 16.2 2.5 0.014 15.0 1.7 1.7 1 0 0 1 1 1 1 Uncharacterised protein family UPF0547 DUF3797 PF12677.2 EIW76418.1 - 0.15 11.6 0.6 0.9 9.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) zf-FPG_IleRS PF06827.9 EIW76418.1 - 1.5 8.5 6.2 3.9 7.2 0.0 3.3 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS WD40 PF00400.27 EIW76419.1 - 1.4e-31 107.1 16.6 3.3e-10 39.4 0.2 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW76419.1 - 0.0019 17.6 2.4 0.028 13.8 0.2 2.6 1 1 1 3 3 3 1 PQQ-like domain Coatomer_WDAD PF04053.9 EIW76419.1 - 0.081 11.7 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region IKI3 PF04762.7 EIW76419.1 - 0.094 10.5 0.0 0.29 8.8 0.0 1.7 3 0 0 3 3 3 0 IKI3 family BACON PF13004.2 EIW76419.1 - 0.35 11.1 0.1 0.35 11.1 0.1 2.6 3 0 0 3 3 3 0 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal Ribosomal_L7Ae PF01248.21 EIW76420.1 - 1.1e-27 95.3 2.7 1.3e-27 95.1 1.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Peptidase_C48 PF02902.14 EIW76421.1 - 2.3e-08 33.9 0.0 4.3e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain His_Phos_2 PF00328.17 EIW76422.1 - 1.4e-47 162.7 0.0 1.7e-47 162.4 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) GvpG PF05120.7 EIW76422.1 - 0.16 11.7 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 Gas vesicle protein G Xan_ur_permease PF00860.15 EIW76423.1 - 2.5e-62 210.6 29.1 1.1e-41 142.6 8.8 2.3 2 0 0 2 2 2 2 Permease family Clathrin PF00637.15 EIW76424.1 - 8.8e-26 90.2 0.1 2.6e-25 88.6 0.0 1.9 2 0 0 2 2 2 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 EIW76424.1 - 5.6e-05 22.8 0.8 0.00014 21.6 0.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIW76424.1 - 0.008 15.8 0.3 0.027 14.1 0.2 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CENP-B_dimeris PF09026.5 EIW76424.1 - 0.0085 16.3 8.8 0.021 15.0 6.1 1.7 1 0 0 1 1 1 1 Centromere protein B dimerisation domain zf-RING_5 PF14634.1 EIW76424.1 - 0.013 15.2 0.2 0.039 13.6 0.2 1.9 1 1 0 1 1 1 0 zinc-RING finger domain WD40 PF00400.27 EIW76424.1 - 0.05 13.4 0.1 0.49 10.3 0.0 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat Vps39_1 PF10366.4 EIW76424.1 - 0.093 12.7 0.3 0.8 9.7 0.0 2.4 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EIW76424.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 Phage_Gp14 PF10666.4 EIW76425.1 - 0.024 14.5 0.1 0.083 12.7 0.0 1.8 2 0 0 2 2 2 0 Phage protein Gp14 HET PF06985.6 EIW76427.1 - 2.8e-18 66.4 10.3 1.3e-16 60.9 2.1 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF1399 PF07173.7 EIW76428.1 - 6.5e-20 71.7 0.5 6.1e-13 49.2 0.0 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF1399) DJ-1_PfpI PF01965.19 EIW76429.1 - 1.4e-06 27.8 0.2 6.8e-06 25.6 0.2 2.0 2 1 0 2 2 2 1 DJ-1/PfpI family DUF4066 PF13278.1 EIW76429.1 - 0.0019 17.4 0.0 0.0048 16.1 0.0 1.6 1 1 0 1 1 1 1 Putative amidotransferase GATase_3 PF07685.9 EIW76429.1 - 0.021 14.4 0.0 0.049 13.2 0.0 1.6 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain HET PF06985.6 EIW76430.1 - 1e-18 67.8 0.9 7.7e-14 52.0 0.0 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.6 EIW76432.1 - 2.9e-18 66.3 1.3 3.2e-14 53.2 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) CBM_5_12 PF02839.9 EIW76434.1 - 0.00012 21.5 3.4 0.00012 21.5 2.4 1.9 2 0 0 2 2 2 1 Carbohydrate binding domain HET PF06985.6 EIW76435.1 - 2.8e-17 63.1 5.1 1.5e-14 54.3 0.2 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) GFA PF04828.9 EIW76436.1 - 5.6e-25 87.1 1.6 7.3e-25 86.7 1.1 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Tim17 PF02466.14 EIW76437.1 - 0.14 12.2 10.5 0.53 10.3 0.0 3.6 4 0 0 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family BNIP2 PF12496.3 EIW76437.1 - 0.16 12.1 0.6 0.27 11.4 0.4 1.2 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 HET PF06985.6 EIW76438.1 - 6.2e-17 62.0 6.5 1.7e-14 54.1 0.3 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.6 EIW76439.1 - 1.6e-19 70.4 1.6 6.9e-16 58.6 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) His_Phos_2 PF00328.17 EIW76440.1 - 1.1e-36 126.9 0.0 1.8e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF1399 PF07173.7 EIW76441.1 - 7.2e-16 58.7 0.3 8.1e-10 39.1 0.1 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF1399) Retrotrans_gag PF03732.12 EIW76442.1 - 0.00035 20.5 0.0 0.0018 18.3 0.0 2.1 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_5 PF14787.1 EIW76442.1 - 0.00075 18.9 1.9 0.0012 18.2 1.3 1.4 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.18 EIW76442.1 - 0.1 12.5 2.1 0.16 11.9 1.4 1.3 1 0 0 1 1 1 0 Zinc knuckle FAM72 PF14976.1 EIW76443.1 - 0.75 9.6 0.9 1.3 8.8 0.6 1.2 1 0 0 1 1 1 0 FAM72 protein DUF737 PF05300.6 EIW76443.1 - 4.2 7.2 6.9 1.8 8.5 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF737) F-box-like PF12937.2 EIW76444.1 - 0.0022 17.6 1.0 0.0046 16.6 0.1 2.1 2 0 0 2 2 2 1 F-box-like HET PF06985.6 EIW76445.1 - 4.2e-17 62.5 5.2 1.2e-14 54.6 0.1 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_trans_2_3 PF13632.1 EIW76445.1 - 0.081 12.6 0.1 0.14 11.8 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family group 2 p450 PF00067.17 EIW76447.1 - 5.9e-70 236.0 0.0 6.6e-70 235.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CBM_5_12 PF02839.9 EIW76448.1 - 2.5e-12 46.1 27.2 6.8e-08 31.9 7.2 3.8 4 1 1 5 5 5 2 Carbohydrate binding domain Tmp39 PF10271.4 EIW76448.1 - 0.32 9.6 0.7 0.48 9.0 0.5 1.2 1 0 0 1 1 1 0 Putative transmembrane protein Glyco_hydro_7 PF00840.15 EIW76449.1 - 3.6e-211 701.1 23.7 4.2e-211 700.9 16.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF2215 PF10225.4 EIW76451.1 - 6.2 6.1 7.0 35 3.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) Pro-kuma_activ PF09286.6 EIW76452.1 - 5.2e-34 117.3 0.1 9.3e-34 116.5 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIW76452.1 - 1.2e-07 31.1 0.1 2.1e-07 30.3 0.1 1.6 1 1 0 1 1 1 1 Subtilase family NAD_binding_8 PF13450.1 EIW76453.1 - 0.1 12.6 0.3 0.29 11.1 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NMN_transporter PF04973.7 EIW76454.1 - 0.075 12.4 2.6 0.13 11.6 0.2 2.0 2 0 0 2 2 2 0 Nicotinamide mononucleotide transporter DUF1399 PF07173.7 EIW76457.1 - 1.9e-24 86.4 0.0 4.1e-18 65.9 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF1399) DUF1399 PF07173.7 EIW76458.1 - 0.013 15.7 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1399) DUF1399 PF07173.7 EIW76459.1 - 9.8e-10 38.8 1.7 1.4e-09 38.3 0.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1399) Slx4 PF09494.5 EIW76459.1 - 0.14 11.9 0.1 0.19 11.5 0.1 1.2 1 0 0 1 1 1 0 Slx4 endonuclease MatE PF01554.13 EIW76460.1 - 0.018 14.6 3.1 0.086 12.4 0.0 2.2 2 0 0 2 2 2 0 MatE Orai-1 PF07856.7 EIW76460.1 - 2.3 7.7 5.8 2.9 7.4 4.0 1.4 1 1 0 1 1 1 0 Mediator of CRAC channel activity Peptidase_S64 PF08192.6 EIW76461.1 - 0.0028 16.0 0.0 0.005 15.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S64 Trypsin_2 PF13365.1 EIW76461.1 - 0.018 14.9 0.1 0.13 12.2 0.0 2.3 1 1 0 1 1 1 0 Trypsin-like peptidase domain Peptidase_S32 PF05579.8 EIW76461.1 - 0.15 10.9 0.9 0.47 9.3 0.2 1.9 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 DUF1793 PF08760.6 EIW76463.1 - 1e-58 197.9 1.1 1e-58 197.9 0.8 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) CBM_5_12 PF02839.9 EIW76464.1 - 7.3e-11 41.4 34.2 7.3e-08 31.8 7.4 3.8 3 2 0 3 3 3 2 Carbohydrate binding domain CBM_5_12_2 PF14600.1 EIW76464.1 - 3.6e-05 23.3 19.9 0.0047 16.5 6.1 2.8 2 1 0 2 2 2 2 Cellulose-binding domain Tmp39 PF10271.4 EIW76464.1 - 0.32 9.5 0.8 0.48 9.0 0.6 1.2 1 0 0 1 1 1 0 Putative transmembrane protein Chitin_synth_2 PF03142.10 EIW76465.1 - 2e-239 795.3 0.1 2.6e-239 795.0 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EIW76465.1 - 1.6e-115 386.7 0.0 4.7e-115 385.2 0.0 1.7 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_trans_2_3 PF13632.1 EIW76465.1 - 1.2e-18 67.5 1.8 3.8e-18 65.8 1.2 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIW76465.1 - 3.6e-18 66.2 0.0 2e-14 53.9 0.0 2.8 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EIW76465.1 - 2.3e-17 62.5 0.1 3.8e-11 42.6 0.0 3.2 3 0 0 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EIW76465.1 - 4.5e-12 45.5 1.6 9.2e-11 41.3 0.7 2.7 3 0 0 3 3 3 1 DEK C terminal domain Glycos_transf_2 PF00535.21 EIW76465.1 - 4.3e-08 33.0 0.0 3.1e-05 23.7 0.0 2.6 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIW76465.1 - 8.2e-06 25.2 0.0 0.00097 18.4 0.0 3.2 3 0 0 3 3 3 1 Glycosyl transferase family 21 F-box-like PF12937.2 EIW76466.1 - 1.1e-06 28.3 0.2 4.3e-06 26.3 0.1 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW76466.1 - 3.4e-06 26.5 0.5 0.00012 21.6 0.1 3.1 3 0 0 3 3 3 1 F-box domain DUF4428 PF14471.1 EIW76466.1 - 0.0007 19.2 0.0 0.0021 17.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4428) Prim_Zn_Ribbon PF08273.7 EIW76466.1 - 0.07 13.2 10.6 12 6.0 0.1 4.0 3 1 0 3 3 3 0 Zinc-binding domain of primase-helicase SKG6 PF08693.5 EIW76467.1 - 9.5 5.6 6.3 0.49 9.7 0.4 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Coatomer_WDAD PF04053.9 EIW76468.1 - 1.5e-146 488.6 0.0 3e-146 487.7 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.27 EIW76468.1 - 4.6e-50 165.7 9.2 4.1e-09 35.9 0.0 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 EIW76468.1 - 9.1e-05 22.2 0.0 12 5.7 0.0 5.0 3 1 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region RXT2_N PF08595.6 EIW76468.1 - 0.0015 18.3 2.0 0.0032 17.2 1.4 1.4 1 0 0 1 1 1 1 RXT2-like, N-terminal CobT PF06213.7 EIW76468.1 - 0.0029 16.7 4.5 0.0047 16.0 3.1 1.2 1 0 0 1 1 1 1 Cobalamin biosynthesis protein CobT Nup160 PF11715.3 EIW76468.1 - 0.021 13.0 2.8 4.6 5.2 0.2 3.6 2 1 0 3 3 3 0 Nucleoporin Nup120/160 DUF4611 PF15387.1 EIW76468.1 - 0.4 10.8 9.4 1 9.5 6.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF2457 PF10446.4 EIW76468.1 - 0.44 9.2 16.0 0.65 8.6 11.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Sigma70_ner PF04546.8 EIW76468.1 - 0.59 9.7 11.6 1 8.9 8.1 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Sporozoite_P67 PF05642.6 EIW76468.1 - 0.99 7.1 5.9 1.6 6.4 4.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nucleoplasmin PF03066.10 EIW76468.1 - 1.3 8.4 16.5 2.4 7.6 11.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin CENP-B_dimeris PF09026.5 EIW76468.1 - 6.3 7.0 18.8 12 6.1 13.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CBM_5_12 PF02839.9 EIW76469.1 - 0.0083 15.6 0.1 0.013 15.0 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain His_Phos_2 PF00328.17 EIW76471.1 - 1.7e-51 175.5 0.0 2e-51 175.3 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Pro-kuma_activ PF09286.6 EIW76473.1 - 2.3e-37 128.2 0.1 4e-37 127.4 0.1 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIW76473.1 - 8.5e-08 31.6 0.3 1.9e-07 30.5 0.1 1.6 1 1 1 2 2 2 1 Subtilase family H_PPase PF03030.11 EIW76473.1 - 0.031 12.5 0.2 0.045 12.0 0.2 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase Alpha_L_fucos PF01120.12 EIW76474.1 - 5e-79 265.7 4.4 6.8e-79 265.2 3.1 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase DUF3328 PF11807.3 EIW76475.1 - 2.8e-21 76.1 2.1 3.3e-21 75.9 1.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) APC_crr PF05923.7 EIW76476.1 - 0.076 12.6 4.7 1.5e+02 2.2 0.0 6.2 7 0 0 7 7 7 0 APC cysteine-rich region DUF4653 PF15546.1 EIW76476.1 - 0.96 8.6 4.4 1.9 7.6 3.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4653) Herpes_LMP1 PF05297.6 EIW76476.1 - 3 6.6 10.4 9.6 5.0 7.3 1.7 1 1 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF3328 PF11807.3 EIW76479.1 - 3.2e-14 53.1 1.0 9.5e-14 51.5 0.7 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.11 EIW76480.1 - 1.6e-36 125.7 44.0 1.6e-36 125.7 30.5 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIW76480.1 - 2e-10 39.5 10.8 3.4e-10 38.7 7.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIW76480.1 - 3.4e-10 39.0 42.3 1.4e-07 30.4 10.2 3.7 1 1 2 4 4 4 2 Sugar (and other) transporter Ferric_reduct PF01794.14 EIW76481.1 - 0.19 11.8 6.5 0.056 13.5 1.7 2.1 1 1 1 2 2 2 0 Ferric reductase like transmembrane component Glyco_hydro_71 PF03659.9 EIW76482.1 - 7.4e-97 324.2 12.5 8.7e-97 324.0 8.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Lipase_GDSL_2 PF13472.1 EIW76483.1 - 7.7e-06 26.1 0.2 1e-05 25.7 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EIW76483.1 - 0.0068 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyco_hydro_7 PF00840.15 EIW76484.1 - 1.9e-209 695.4 27.6 2.2e-209 695.2 19.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Abhydrolase_6 PF12697.2 EIW76485.1 - 4.6e-32 111.7 0.1 5.5e-32 111.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW76485.1 - 3.4e-16 59.3 0.0 4.9e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW76485.1 - 8.1e-15 54.9 0.2 1.4e-13 50.9 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EIW76485.1 - 3.5e-09 36.4 0.0 5.1e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 EIW76485.1 - 1.1e-05 25.1 0.0 5.7e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EIW76485.1 - 0.00082 18.6 0.0 0.054 12.6 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 EIW76485.1 - 0.0074 15.6 0.1 0.092 12.0 0.1 2.4 2 1 0 2 2 2 1 Dienelactone hydrolase family FSH1 PF03959.8 EIW76485.1 - 0.025 14.0 0.1 0.19 11.1 0.1 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EIW76485.1 - 0.076 12.4 0.1 0.61 9.4 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Myb_DNA-bind_6 PF13921.1 EIW76493.1 - 3.3e-10 39.9 0.2 7.7e-10 38.7 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIW76493.1 - 8.4e-10 38.5 0.5 2e-09 37.3 0.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Pro-kuma_activ PF09286.6 EIW76497.1 - 2.3e-39 134.7 0.1 1.2e-38 132.3 0.2 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIW76497.1 - 1.1e-06 27.9 3.2 1.7e-06 27.3 0.1 2.0 1 1 0 2 2 2 1 Subtilase family TPT PF03151.11 EIW76498.1 - 7.6 6.1 9.3 0.34 10.5 0.7 2.4 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF3329 PF11808.3 EIW76499.1 - 0.2 11.7 3.4 10 6.2 0.7 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) PLA2_B PF01735.13 EIW76500.1 - 1.2e-104 350.2 1.9 1.6e-104 349.8 1.3 1.1 1 0 0 1 1 1 1 Lysophospholipase catalytic domain dCMP_cyt_deam_2 PF08211.6 EIW76500.1 - 0.083 12.9 0.5 0.17 11.8 0.3 1.5 1 0 0 1 1 1 0 Cytidine and deoxycytidylate deaminase zinc-binding region DUF1996 PF09362.5 EIW76501.1 - 4.4e-77 258.9 0.2 5.4e-77 258.6 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) GST_N_3 PF13417.1 EIW76502.1 - 1.7e-08 34.5 0.0 3.6e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW76502.1 - 3.8e-05 23.6 0.0 9.1e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW76502.1 - 0.0013 18.6 0.0 0.0022 17.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW76502.1 - 0.0014 19.0 0.1 0.0024 18.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW76502.1 - 0.0042 17.2 0.0 0.011 15.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW76502.1 - 0.084 12.7 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain AvrD PF05655.6 EIW76502.1 - 0.13 11.1 0.0 0.63 8.8 0.0 1.8 2 0 0 2 2 2 0 Pseudomonas avirulence D protein (AvrD) zf-C2H2 PF00096.21 EIW76503.1 - 0.0028 17.8 3.5 0.16 12.3 0.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW76503.1 - 0.025 14.9 1.9 2.8 8.4 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger p450 PF00067.17 EIW76504.1 - 1.6e-61 208.3 0.0 2.8e-61 207.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Dimer_Tnp_hAT PF05699.9 EIW76506.1 - 4.8e-15 54.9 0.1 6.1e-15 54.6 0.1 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region F-box-like PF12937.2 EIW76507.1 - 1.1e-06 28.2 0.3 2.7e-06 27.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like PLA2_B PF01735.13 EIW76508.1 - 1.3e-89 300.6 1.1 5e-89 298.7 0.8 1.8 1 1 0 1 1 1 1 Lysophospholipase catalytic domain p450 PF00067.17 EIW76509.1 - 1.2e-64 218.6 0.0 1.5e-64 218.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.8 EIW76510.1 - 1.7e-59 200.9 0.0 2.1e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EIW76510.1 - 2.2e-08 33.2 0.0 5.8e-08 31.8 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 EIW76510.1 - 0.00027 19.7 0.0 0.00036 19.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EIW76510.1 - 0.0066 16.2 0.0 0.0085 15.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EIW76510.1 - 0.014 14.2 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.15 EIW76510.1 - 0.024 14.0 0.3 0.48 9.8 0.2 2.1 1 1 0 1 1 1 0 Putative esterase Peptidase_S9 PF00326.16 EIW76510.1 - 0.12 11.6 0.0 0.22 10.7 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF2416 PF10315.4 EIW76511.1 - 5.1e-15 55.6 2.9 9e-15 54.8 2.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2416) SEEEED PF14797.1 EIW76513.1 - 3 7.9 10.0 1.3 9.1 5.0 1.7 1 1 1 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex Sugar_tr PF00083.19 EIW76514.1 - 8.6e-78 261.9 20.6 1e-77 261.6 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW76514.1 - 3.3e-28 98.4 29.3 2.8e-24 85.5 5.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIW76514.1 - 1.5e-07 30.0 1.0 1.5e-07 30.0 0.7 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 EIW76514.1 - 0.0012 17.6 0.7 0.003 16.3 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF791) DUF2296 PF10058.4 EIW76515.1 - 1.7e-20 72.4 0.2 3.4e-20 71.5 0.2 1.5 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) PhnA_Zn_Ribbon PF08274.7 EIW76515.1 - 0.079 12.7 1.6 0.23 11.2 1.1 1.7 1 1 1 2 2 2 0 PhnA Zinc-Ribbon Zn_Tnp_IS1595 PF12760.2 EIW76515.1 - 0.12 12.1 2.0 0.13 12.0 0.5 1.7 1 1 0 1 1 1 0 Transposase zinc-ribbon domain PAT1 PF09770.4 EIW76515.1 - 1.2 7.3 10.5 1.6 6.8 7.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1610 PF07754.6 EIW76515.1 - 2.3 8.4 5.2 0.26 11.4 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) DUF3460 PF11943.3 EIW76516.1 - 0.089 12.8 0.3 0.21 11.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) Hydrophobin PF01185.13 EIW76517.1 - 9.8e-18 64.3 11.2 1.2e-17 64.1 7.8 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Glyco_hydro_45 PF02015.11 EIW76517.1 - 0.012 15.6 2.4 0.014 15.4 1.7 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 45 Sar8_2 PF03058.9 EIW76517.1 - 0.078 13.3 0.9 0.099 12.9 0.6 1.1 1 0 0 1 1 1 0 Sar8.2 family ABC_tran PF00005.22 EIW76518.1 - 8.7e-48 162.1 0.2 1.1e-24 87.2 0.0 3.0 4 0 0 4 4 2 2 ABC transporter ABC_tran_2 PF12848.2 EIW76518.1 - 5.5e-21 74.2 3.8 5.5e-21 74.2 2.7 2.3 3 0 0 3 3 2 1 ABC transporter AAA_21 PF13304.1 EIW76518.1 - 1.5e-19 71.1 0.7 0.00058 19.9 0.0 4.4 4 0 0 4 4 4 4 AAA domain AAA_29 PF13555.1 EIW76518.1 - 1.2e-10 40.7 0.2 3.1e-05 23.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EIW76518.1 - 5.9e-10 38.7 1.2 0.24 10.6 0.0 4.5 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EIW76518.1 - 1.5e-08 35.2 8.4 0.0013 19.1 0.3 3.6 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EIW76518.1 - 2.7e-08 34.0 0.0 0.00036 20.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_10 PF12846.2 EIW76518.1 - 2.4e-06 27.1 0.1 0.36 10.2 0.0 3.4 3 0 0 3 3 3 2 AAA-like domain DUF258 PF03193.11 EIW76518.1 - 4.6e-06 25.9 0.2 0.0015 17.6 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIW76518.1 - 1.4e-05 25.2 0.0 0.095 12.8 0.0 3.1 2 1 0 2 2 2 2 AAA domain Miro PF08477.8 EIW76518.1 - 1.5e-05 25.4 0.0 0.36 11.3 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EIW76518.1 - 1.7e-05 24.7 0.1 0.024 14.5 0.0 3.2 4 0 0 4 4 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EIW76518.1 - 2.1e-05 24.1 0.0 0.19 11.1 0.0 2.8 3 0 0 3 3 2 2 FtsK/SpoIIIE family NACHT PF05729.7 EIW76518.1 - 2.4e-05 24.0 0.1 0.069 12.7 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_17 PF13207.1 EIW76518.1 - 2.5e-05 25.0 0.9 0.13 13.0 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EIW76518.1 - 9.2e-05 21.9 0.0 1.5 8.2 0.0 3.4 3 0 0 3 3 3 1 AAA domain SbcCD_C PF13558.1 EIW76518.1 - 0.00077 19.3 0.0 0.093 12.6 0.0 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 EIW76518.1 - 0.0021 18.0 0.0 0.26 11.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EIW76518.1 - 0.0024 18.1 0.3 5.6 7.2 0.0 3.5 3 1 0 3 3 3 0 AAA domain AAA_14 PF13173.1 EIW76518.1 - 0.0028 17.5 0.0 5.1 7.0 0.0 4.2 4 0 0 4 4 4 0 AAA domain AAA_30 PF13604.1 EIW76518.1 - 0.0039 16.7 0.0 0.74 9.3 0.0 3.0 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIW76518.1 - 0.0042 17.2 2.1 4.3 7.5 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_33 PF13671.1 EIW76518.1 - 0.0052 16.6 0.0 3.7 7.4 0.0 3.1 3 0 0 3 3 2 1 AAA domain Dynamin_N PF00350.18 EIW76518.1 - 0.0052 16.6 9.3 0.56 10.0 0.3 4.2 2 2 1 3 3 3 2 Dynamin family DUF87 PF01935.12 EIW76518.1 - 0.0055 16.5 6.0 0.79 9.4 0.0 3.8 5 1 0 5 5 3 2 Domain of unknown function DUF87 AAA_13 PF13166.1 EIW76518.1 - 0.0083 14.6 3.2 0.35 9.2 0.0 3.2 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 EIW76518.1 - 0.009 15.7 0.2 12 5.6 0.0 3.3 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EIW76518.1 - 0.013 14.9 0.3 5.7 6.3 0.1 3.0 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain KAP_NTPase PF07693.9 EIW76518.1 - 0.021 13.8 0.0 2.4 7.0 0.0 2.5 2 1 0 2 2 2 0 KAP family P-loop domain ArgK PF03308.11 EIW76518.1 - 0.048 12.4 0.0 7.7 5.2 0.0 2.7 2 0 0 2 2 2 0 ArgK protein NTPase_1 PF03266.10 EIW76518.1 - 0.054 13.2 1.6 9.5 5.9 0.0 3.3 4 0 0 4 4 3 0 NTPase G-alpha PF00503.15 EIW76518.1 - 0.06 12.0 1.6 2.9 6.4 0.1 2.7 2 1 0 2 2 2 0 G-protein alpha subunit ATP-synt_ab PF00006.20 EIW76518.1 - 0.099 12.1 1.2 2.7 7.4 0.0 3.0 3 1 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 EIW76518.1 - 0.12 12.0 1.0 8.6 6.0 0.0 3.2 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) Thymidylate_kin PF02223.12 EIW76518.1 - 0.57 9.5 4.8 23 4.3 0.0 3.7 4 0 0 4 4 4 0 Thymidylate kinase MARVEL PF01284.18 EIW76519.1 - 0.0021 17.8 9.4 0.0038 17.0 6.5 1.3 1 0 0 1 1 1 1 Membrane-associating domain Metallophos PF00149.23 EIW76520.1 - 3.6e-42 144.0 0.4 4.5e-42 143.7 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIW76520.1 - 0.013 15.3 0.0 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain zf-C2H2 PF00096.21 EIW76521.1 - 4.6e-09 36.0 8.6 9.8e-07 28.7 0.8 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW76521.1 - 6.1e-09 35.7 10.4 2e-05 24.6 3.1 2.4 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIW76521.1 - 1.1e-05 25.4 8.8 6.4e-05 23.0 0.6 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIW76521.1 - 0.0033 17.5 1.0 0.005 16.9 0.0 1.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EIW76521.1 - 0.0085 15.8 0.5 0.0085 15.8 0.4 1.9 2 1 0 2 2 2 1 BED zinc finger zf-met PF12874.2 EIW76521.1 - 0.02 15.0 3.9 0.041 14.1 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EIW76521.1 - 0.044 13.7 0.2 0.13 12.1 0.1 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger IBR PF01485.16 EIW76521.1 - 0.081 12.8 4.1 0.55 10.1 0.5 2.1 1 1 1 2 2 2 0 IBR domain zf-TRAF PF02176.13 EIW76521.1 - 0.32 11.3 5.3 0.5 10.7 3.7 1.4 1 0 0 1 1 1 0 TRAF-type zinc finger zf-Di19 PF05605.7 EIW76521.1 - 0.74 9.9 5.4 3 8.0 3.8 2.0 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding F-box-like PF12937.2 EIW76523.1 - 0.00026 20.6 1.6 0.0021 17.7 1.1 2.6 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIW76523.1 - 0.06 12.9 0.0 1.6 8.4 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) SUI1 PF01253.17 EIW76524.1 - 8.6e-20 70.3 0.5 1.8e-19 69.3 0.4 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 EIW76524.1 - 0.012 15.5 0.7 0.019 14.8 0.5 1.3 1 0 0 1 1 1 0 Transposon-encoded protein TnpV Zn_clus PF00172.13 EIW76525.1 - 5.4e-07 29.4 7.5 8.9e-07 28.7 5.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PI-PLC-X PF00388.14 EIW76526.1 - 1.2e-55 186.8 0.0 2.3e-55 186.0 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EIW76526.1 - 6.4e-39 132.5 0.0 1.8e-38 131.1 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EIW76526.1 - 2.3e-11 43.3 0.1 0.00032 20.4 0.0 3.0 3 0 0 3 3 3 2 C2 domain EF-hand_like PF09279.6 EIW76526.1 - 4.5e-07 29.8 3.5 0.012 15.5 0.0 3.5 3 0 0 3 3 3 2 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_10 PF14788.1 EIW76526.1 - 0.00096 18.7 2.1 0.0026 17.3 0.3 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EIW76526.1 - 0.014 15.0 0.9 4 7.1 0.1 2.7 2 0 0 2 2 2 0 EF-hand domain pair MSG PF02349.10 EIW76526.1 - 0.021 14.7 1.3 0.48 10.4 0.0 2.7 3 0 0 3 3 3 0 Major surface glycoprotein EF-hand_7 PF13499.1 EIW76526.1 - 0.024 14.7 1.2 0.2 11.8 0.2 2.4 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.27 EIW76526.1 - 0.21 10.9 0.4 1.2 8.5 0.1 2.5 2 0 0 2 2 2 0 EF hand DSPc PF00782.15 EIW76527.1 - 5.1e-33 113.4 0.1 7.9e-33 112.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIW76527.1 - 2.9e-05 23.5 0.1 3.8e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EIW76527.1 - 0.028 14.4 0.1 0.045 13.7 0.1 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate DUF4646 PF15496.1 EIW76528.1 - 2.2e-23 82.6 0.0 3.4e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) Peptidase_M3 PF01432.15 EIW76529.1 - 9.8e-133 443.5 0.0 1.4e-132 443.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 EIW76529.1 - 0.017 14.5 0.1 0.029 13.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like DDOST_48kD PF03345.9 EIW76529.1 - 0.062 11.8 0.1 0.1 11.1 0.1 1.2 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta BURP PF03181.10 EIW76532.1 - 0.05 12.7 0.6 0.076 12.1 0.4 1.2 1 0 0 1 1 1 0 BURP domain P33MONOX PF15302.1 EIW76533.1 - 0.039 13.5 4.1 0.039 13.5 2.9 1.0 1 0 0 1 1 1 0 P33 mono-oxygenase Siah-Interact_N PF09032.6 EIW76533.1 - 0.17 11.9 5.5 0.085 12.9 0.9 1.9 2 0 0 2 2 2 0 Siah interacting protein, N terminal NST1 PF13945.1 EIW76533.1 - 2.2 8.3 5.4 2.5 8.1 3.7 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Pol_alpha_B_N PF08418.5 EIW76533.1 - 3.1 7.2 6.7 3.7 7.0 4.6 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal MSA-2c PF12238.3 EIW76533.1 - 4.6 6.8 7.7 5.2 6.6 5.4 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c DUF3774 PF12609.3 EIW76533.1 - 7.9 7.4 6.8 15 6.4 4.7 1.6 1 1 0 1 1 1 0 Wound-induced protein Cellulase PF00150.13 EIW76534.1 - 2.5e-49 167.9 1.6 3.2e-49 167.6 1.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GATase_5 PF13507.1 EIW76534.1 - 0.052 12.4 0.0 0.085 11.7 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Pro-kuma_activ PF09286.6 EIW76535.1 - 1.3e-23 83.6 1.0 5.8e-23 81.5 0.2 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIW76535.1 - 6.2e-12 45.2 0.8 6.2e-12 45.2 0.6 2.0 1 1 1 2 2 2 1 Subtilase family NUDIX PF00293.23 EIW76536.1 - 1.4e-13 50.6 0.0 2.5e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain ARD PF03079.9 EIW76537.1 - 8.5e-46 155.7 0.1 9.8e-46 155.5 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EIW76537.1 - 1.4e-09 37.2 0.3 2.6e-09 36.4 0.2 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EIW76537.1 - 3.9e-06 26.5 0.0 6.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EIW76537.1 - 0.00021 20.7 0.0 0.00031 20.2 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EIW76537.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_8 PF13621.1 EIW76537.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.3 1 1 0 1 1 1 0 Cupin-like domain PIF1 PF05970.9 EIW76538.1 - 2e-54 184.9 0.3 9.7e-44 149.7 0.0 3.1 3 0 0 3 3 3 3 PIF1-like helicase AAA_30 PF13604.1 EIW76538.1 - 1.1e-19 70.7 0.0 3.3e-19 69.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW76538.1 - 7.5e-07 28.8 0.4 4.8e-06 26.2 0.1 2.6 2 0 0 2 2 1 1 Part of AAA domain AAA_22 PF13401.1 EIW76538.1 - 1e-06 28.8 0.0 2.6e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain Herpes_Helicase PF02689.9 EIW76538.1 - 5.2e-05 21.2 0.3 0.0009 17.1 0.0 2.4 2 0 0 2 2 2 1 Helicase AAA_11 PF13086.1 EIW76538.1 - 0.00024 20.7 4.3 0.064 12.8 0.0 3.2 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.1 EIW76538.1 - 0.00032 20.7 0.2 0.0018 18.2 0.1 2.3 1 1 0 1 1 1 1 AAA ATPase domain UvrD_C_2 PF13538.1 EIW76538.1 - 0.00068 19.7 0.3 0.0037 17.3 0.0 2.3 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain PhoH PF02562.11 EIW76538.1 - 0.00088 18.5 0.1 0.0038 16.4 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein T2SE PF00437.15 EIW76538.1 - 0.0071 15.2 0.0 0.015 14.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.24 EIW76538.1 - 0.011 15.9 0.1 0.039 14.1 0.0 2.0 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIW76538.1 - 0.019 14.7 0.0 0.1 12.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EIW76538.1 - 0.027 13.6 0.1 0.051 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF2075 PF09848.4 EIW76538.1 - 0.028 13.4 0.0 0.073 12.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 EIW76538.1 - 0.028 14.0 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.13 EIW76538.1 - 0.032 13.7 4.6 0.6 9.5 0.1 3.7 3 1 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 EIW76538.1 - 0.05 13.1 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 EIW76538.1 - 0.051 13.7 0.0 0.15 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_14 PF13173.1 EIW76538.1 - 0.12 12.2 0.0 0.82 9.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain RNA_pol_Rpc4 PF05132.9 EIW76538.1 - 0.99 9.3 8.3 5.3 7.0 0.1 2.8 3 0 0 3 3 2 0 RNA polymerase III RPC4 DUF966 PF06136.8 EIW76538.1 - 1.2 8.4 12.7 3.2 7.0 8.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF2217 PF10265.4 EIW76538.1 - 3 6.5 7.8 7.3 5.2 5.4 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) Sec3_C PF09763.4 EIW76538.1 - 5.4 5.0 7.5 9.6 4.1 5.2 1.3 1 0 0 1 1 1 0 Exocyst complex component Sec3 F-box-like PF12937.2 EIW76539.1 - 7.9e-11 41.5 2.8 2.7e-10 39.7 1.9 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EIW76539.1 - 4.6 7.0 10.2 1.6e+02 2.1 5.9 3.5 2 1 0 2 2 2 0 F-box domain ARD PF03079.9 EIW76540.1 - 1.4e-44 151.8 0.1 1.6e-44 151.6 0.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EIW76540.1 - 8.7e-10 37.9 0.1 2e-09 36.8 0.1 1.6 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EIW76540.1 - 1.9e-07 30.8 0.1 2.7e-07 30.3 0.1 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EIW76540.1 - 0.0012 18.2 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EIW76540.1 - 0.0066 15.8 0.0 0.012 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_8 PF13621.1 EIW76540.1 - 0.024 14.1 0.0 0.048 13.1 0.0 1.4 1 1 0 1 1 1 0 Cupin-like domain DOPA_dioxygen PF08883.6 EIW76545.1 - 4.4e-31 107.0 0.1 5.1e-31 106.8 0.1 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family dCMP_cyt_deam_1 PF00383.17 EIW76547.1 - 2.9e-12 46.1 0.1 2.1e-11 43.3 0.1 1.9 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region NST1 PF13945.1 EIW76550.1 - 1.7e-42 145.6 1.6 1.7e-42 145.6 1.1 3.6 3 1 0 3 3 3 1 Salt tolerance down-regulator TFIIA PF03153.8 EIW76550.1 - 3.3e-06 27.2 12.0 3.3e-06 27.2 8.3 2.4 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit mIF3 PF14877.1 EIW76551.1 - 0.057 12.7 6.1 0.063 12.6 4.3 1.1 1 0 0 1 1 1 0 Mitochondrial translation initiation factor YebO PF13974.1 EIW76551.1 - 0.087 12.6 4.4 0.12 12.1 3.0 1.3 1 0 0 1 1 1 0 YebO-like protein Peroxin-13_N PF04088.8 EIW76551.1 - 0.1 12.5 1.6 0.12 12.3 1.1 1.0 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Asp-B-Hydro_N PF05279.6 EIW76551.1 - 0.56 10.0 6.6 0.61 9.8 4.6 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF4047 PF13256.1 EIW76551.1 - 0.91 9.4 6.1 0.98 9.3 4.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) DUF1663 PF07909.6 EIW76551.1 - 0.98 7.8 7.0 1.1 7.7 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1663) DUF3987 PF13148.1 EIW76551.1 - 2.7 6.4 7.5 3.2 6.1 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) RAI1 PF08652.6 EIW76551.1 - 4.3 7.1 6.4 4.4 7.1 3.7 1.7 1 1 1 2 2 2 0 RAI1 like PD-(D/E)XK nuclease DUF2924 PF11149.3 EIW76551.1 - 5 7.1 6.5 5.5 7.0 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) Topoisom_I_N PF02919.10 EIW76551.1 - 5.9 6.1 8.5 7.5 5.7 5.9 1.4 1 1 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment CR6_interact PF10147.4 EIW76551.1 - 7.6 5.7 16.7 8.7 5.5 11.6 1.0 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 E1-E2_ATPase PF00122.15 EIW76552.1 - 4.2e-23 81.5 0.0 4.2e-23 81.5 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EIW76552.1 - 3.3e-17 63.6 0.1 2.7e-16 60.6 0.1 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIW76552.1 - 3.7e-13 50.0 0.1 7e-13 49.1 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIW76552.1 - 1.8e-05 24.5 0.0 5e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EIW76552.1 - 0.00037 20.1 0.0 0.00087 18.9 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Peptidase_M16 PF00675.15 EIW76553.1 - 1.6e-20 73.3 0.4 3.2e-20 72.4 0.0 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EIW76553.1 - 1.3e-09 38.0 0.0 2.8e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase M16 inactive domain PTS_IIA PF02255.11 EIW76553.1 - 2.1 8.2 6.5 11 6.0 1.8 2.6 1 1 1 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit Methyltransf_23 PF13489.1 EIW76554.1 - 1.3e-12 47.7 0.0 2e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW76554.1 - 4.2e-11 43.1 0.0 8e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW76554.1 - 2.8e-10 40.0 0.0 9.7e-10 38.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW76554.1 - 1.3e-06 28.9 0.0 2.4e-05 24.8 0.0 2.7 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIW76554.1 - 1.5e-05 24.1 0.0 0.013 14.5 0.0 3.1 3 0 0 3 3 3 1 Putative methyltransferase Methyltransf_12 PF08242.7 EIW76554.1 - 2.1e-05 24.8 0.0 7.7e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIW76554.1 - 0.0015 18.1 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Ubie_methyltran PF01209.13 EIW76554.1 - 0.0018 17.4 0.0 0.022 13.8 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EIW76554.1 - 0.002 18.1 0.0 0.0084 16.1 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW76554.1 - 0.0027 18.0 0.0 0.0074 16.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 EIW76554.1 - 0.0034 15.7 0.0 0.02 13.2 0.0 1.9 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase FtsJ PF01728.14 EIW76554.1 - 0.0037 17.2 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF938 PF06080.7 EIW76554.1 - 0.0042 16.6 0.0 0.0071 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) MTS PF05175.9 EIW76554.1 - 0.005 16.2 0.0 0.014 14.8 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain DNA_pol_B_palm PF14792.1 EIW76555.1 - 2.8e-26 91.7 0.0 6.2e-26 90.6 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EIW76555.1 - 2.7e-18 65.4 0.0 5.1e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 EIW76555.1 - 1.2e-17 63.1 0.3 1.7e-16 59.4 0.0 2.6 3 0 0 3 3 3 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 EIW76555.1 - 9.6e-16 57.7 0.1 2.5e-15 56.3 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.1 EIW76555.1 - 0.00027 21.0 0.0 0.47 10.6 0.0 2.7 1 1 2 3 3 3 3 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EIW76555.1 - 0.0027 17.9 0.1 0.0062 16.8 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain HHH PF00633.18 EIW76555.1 - 0.082 12.6 0.3 0.32 10.7 0.0 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif HTH_41 PF14502.1 EIW76556.1 - 0.058 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Nop53 PF07767.6 EIW76556.1 - 0.3 10.0 2.5 0.52 9.2 1.7 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF2457 PF10446.4 EIW76556.1 - 1.2 7.8 10.8 5.2 5.6 7.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Nucleo_P87 PF07267.6 EIW76556.1 - 3.1 6.3 4.5 4.4 5.8 3.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 TFIIA PF03153.8 EIW76556.1 - 9.4 6.0 11.2 10 5.9 7.7 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PBP1_TM PF14812.1 EIW76556.1 - 9.9 6.5 15.4 38 4.6 10.6 2.1 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sec3_C PF09763.4 EIW76557.1 - 0.049 11.7 2.3 0.1 10.7 1.6 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec3 GST_C_2 PF13410.1 EIW76564.1 - 2.2e-07 30.6 0.0 3.8e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW76564.1 - 3.9e-07 30.1 0.0 6.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EIW76564.1 - 1.8e-05 24.8 0.0 3.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW76564.1 - 2e-05 24.4 0.0 3.5e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW76564.1 - 0.00013 22.4 0.0 0.00023 21.5 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW76564.1 - 0.00091 19.1 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PEMT PF04191.8 EIW76565.1 - 2.8e-49 165.6 10.8 1.1e-29 102.6 1.1 3.7 4 0 0 4 4 4 2 Phospholipid methyltransferase Aminotran_3 PF00202.16 EIW76566.1 - 3e-108 361.6 0.0 6.7e-108 360.5 0.0 1.5 1 1 1 2 2 2 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EIW76566.1 - 0.0016 17.4 0.0 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIW76566.1 - 0.016 14.3 0.0 0.042 12.9 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase zf-DHHC PF01529.15 EIW76567.1 - 5.8e-32 110.4 14.9 5.8e-32 110.4 10.4 2.3 1 1 1 2 2 2 1 DHHC palmitoyltransferase Mucin PF01456.12 EIW76567.1 - 0.044 13.5 0.0 0.1 12.3 0.0 1.6 1 1 0 1 1 1 0 Mucin-like glycoprotein DUF2456 PF10445.4 EIW76567.1 - 0.17 11.8 2.0 17 5.4 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2456) Cullin_binding PF03556.10 EIW76569.1 - 4.6e-33 113.8 1.7 7.1e-33 113.2 1.2 1.3 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 EIW76569.1 - 3.6e-07 29.6 0.0 7e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain DUF3659 PF12396.3 EIW76573.1 - 0.11 12.1 1.0 0.47 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) Fes1 PF08609.5 EIW76574.1 - 1.1e-21 77.1 0.2 2.7e-21 75.8 0.1 1.7 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 HEAT_EZ PF13513.1 EIW76574.1 - 0.0018 18.7 2.7 0.75 10.3 0.0 3.9 4 1 1 5 5 5 2 HEAT-like repeat HEAT_2 PF13646.1 EIW76574.1 - 0.02 15.1 0.8 0.46 10.7 0.0 2.8 1 1 0 2 2 2 0 HEAT repeats HEAT PF02985.17 EIW76574.1 - 0.036 14.1 0.1 5.6 7.3 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat EF1G PF00647.14 EIW76579.1 - 1.2e-41 140.7 0.1 2.5e-41 139.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.15 EIW76579.1 - 3.1e-08 33.6 0.4 9.1e-08 32.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EIW76579.1 - 8.5e-08 32.3 0.0 2.2e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW76579.1 - 9.9e-08 31.8 0.0 3.3e-07 30.1 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIW76579.1 - 2.6e-07 30.4 0.1 8.5e-07 28.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW76579.1 - 7.8e-05 23.0 0.0 0.0003 21.1 0.0 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW76579.1 - 0.00023 21.0 0.0 0.00068 19.5 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Abhydrolase_5 PF12695.2 EIW76579.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family ORC2 PF04084.9 EIW76580.1 - 1.3e-62 211.5 0.0 1.8e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 p450 PF00067.17 EIW76581.1 - 1.6e-69 234.6 0.0 2e-69 234.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ERG4_ERG24 PF01222.12 EIW76582.1 - 1.8e-138 461.6 3.7 2.1e-138 461.5 2.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family PEMT PF04191.8 EIW76582.1 - 2.4e-06 27.5 0.0 2.4e-06 27.5 0.0 2.8 4 0 0 4 4 4 1 Phospholipid methyltransferase DUF1295 PF06966.7 EIW76582.1 - 1.2e-05 24.7 0.1 1.2e-05 24.7 0.1 2.0 3 0 0 3 3 3 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EIW76582.1 - 0.003 17.7 0.0 0.011 15.9 0.0 2.0 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Dicty_CTDC PF00526.13 EIW76583.1 - 0.029 14.1 1.1 0.1 12.4 0.7 2.0 1 0 0 1 1 1 0 Dictyostelium (slime mold) repeat SET PF00856.23 EIW76584.1 - 4.8e-13 49.7 0.5 1.2e-11 45.1 0.4 2.4 1 1 0 1 1 1 1 SET domain SAF PF08666.7 EIW76584.1 - 0.022 15.1 0.0 13 6.2 0.0 2.6 2 0 0 2 2 2 0 SAF domain DUF2724 PF10893.3 EIW76584.1 - 0.041 13.7 0.1 0.13 12.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) Arg_repressor PF01316.16 EIW76584.1 - 0.097 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain Glyco_hydro_28 PF00295.12 EIW76587.1 - 0.031 13.2 0.0 0.036 13.0 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 28 ADH_zinc_N PF00107.21 EIW76588.1 - 3.5e-25 88.0 0.6 5.4e-25 87.4 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW76588.1 - 1.4e-17 64.8 0.1 2.6e-17 63.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW76588.1 - 3.6e-12 46.0 2.0 8e-12 44.8 0.1 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ATP_synt_I PF03899.10 EIW76590.1 - 3.7 7.7 10.9 2.2 8.5 0.3 3.3 2 1 1 3 3 3 0 ATP synthase I chain GH3 PF03321.8 EIW76591.1 - 1.1e-48 166.0 0.0 1.9e-48 165.3 0.0 1.3 1 1 0 1 1 1 1 GH3 auxin-responsive promoter ADH_zinc_N PF00107.21 EIW76592.1 - 1e-28 99.4 0.3 1.5e-28 98.9 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW76592.1 - 3e-16 60.4 0.1 5.5e-16 59.6 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW76592.1 - 5.6e-09 35.7 0.0 2.1e-08 33.8 0.0 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ABA_GPCR PF12430.3 EIW76593.1 - 7.1e-34 116.6 0.2 7.1e-34 116.6 0.1 1.8 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 EIW76593.1 - 8.4e-07 28.9 0.5 8.4e-07 28.9 0.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) DUF2592 PF10766.4 EIW76593.1 - 0.14 11.5 0.2 0.14 11.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2592) Ank_2 PF12796.2 EIW76594.1 - 1.5e-41 140.6 0.8 7.8e-13 48.5 0.0 4.6 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EIW76594.1 - 2.3e-35 118.6 10.9 1.7e-07 30.7 0.1 7.2 8 0 0 8 8 8 5 Ankyrin repeat zf-DHHC PF01529.15 EIW76594.1 - 9.8e-35 119.5 3.2 3e-34 117.9 0.8 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.1 EIW76594.1 - 6.2e-33 112.0 5.2 1.2e-10 41.3 0.0 5.5 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIW76594.1 - 1.5e-29 101.8 1.5 1.8e-08 34.6 0.0 5.3 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIW76594.1 - 2e-20 70.8 4.7 0.00016 21.6 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeat Serglycin PF04360.7 EIW76594.1 - 0.17 11.6 3.8 0.4 10.4 2.6 1.6 1 0 0 1 1 1 0 Serglycin Pex24p PF06398.6 EIW76594.1 - 0.17 10.6 0.0 0.3 9.8 0.0 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin PocR PF10114.4 EIW76594.1 - 0.34 10.0 2.8 0.54 9.3 1.9 1.2 1 0 0 1 1 1 0 Sensory domain found in PocR ADH_zinc_N PF00107.21 EIW76595.1 - 2e-28 98.5 0.9 3.7e-28 97.6 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW76595.1 - 1.6e-16 61.3 0.4 7.8e-16 59.1 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW76595.1 - 1.4e-08 34.4 0.2 3.4e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SIS_2 PF13580.1 EIW76595.1 - 0.00064 19.4 0.2 0.019 14.6 0.0 2.3 2 0 0 2 2 2 1 SIS domain Methyltransf_31 PF13847.1 EIW76596.1 - 5.4e-10 39.0 0.0 1.5e-09 37.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW76596.1 - 6.9e-10 38.8 0.0 1.1e-09 38.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW76596.1 - 1.3e-09 38.3 0.0 2.3e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW76596.1 - 7e-06 26.3 0.0 1.3e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW76596.1 - 4.9e-05 22.5 0.0 9.5e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EIW76596.1 - 9.7e-05 22.7 0.0 0.00023 21.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW76596.1 - 0.046 14.2 0.0 0.23 12.0 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 EIW76596.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase ADH_zinc_N PF00107.21 EIW76597.1 - 7.9e-27 93.3 0.4 1.5e-26 92.4 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW76597.1 - 1.4e-17 64.7 0.1 3.4e-17 63.5 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW76597.1 - 2.5e-09 36.8 0.3 6.2e-09 35.5 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SIS_2 PF13580.1 EIW76597.1 - 0.027 14.1 0.1 0.17 11.6 0.0 2.0 2 0 0 2 2 2 0 SIS domain PilX PF13681.1 EIW76598.1 - 0.11 13.0 1.8 0.16 12.4 0.9 1.7 1 1 0 1 1 1 0 Type IV pilus assembly protein PilX C-term Hydrophobin PF01185.13 EIW76600.1 - 2.5e-19 69.5 10.7 2.7e-19 69.3 7.4 1.0 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 EIW76601.1 - 7.1e-19 68.0 8.9 8.4e-19 67.8 6.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin GH3 PF03321.8 EIW76602.1 - 1.9e-40 138.8 0.0 2.5e-40 138.5 0.0 1.0 1 0 0 1 1 1 1 GH3 auxin-responsive promoter ADH_zinc_N PF00107.21 EIW76603.1 - 7.5e-27 93.4 0.3 1.1e-26 92.9 0.2 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW76603.1 - 1.7e-18 67.7 0.0 2.7e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CbiJ PF02571.9 EIW76603.1 - 0.075 12.3 0.0 0.45 9.8 0.0 1.9 2 0 0 2 2 2 0 Precorrin-6x reductase CbiJ/CobK ADH_N PF08240.7 EIW76603.1 - 0.075 12.7 0.0 0.25 11.1 0.0 1.9 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Sec66 PF09802.4 EIW76603.1 - 0.13 11.6 0.1 0.19 11.0 0.1 1.2 1 0 0 1 1 1 0 Preprotein translocase subunit Sec66 ADH_zinc_N PF00107.21 EIW76605.1 - 3.6e-26 91.2 0.2 5.8e-26 90.5 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW76605.1 - 1.3e-17 64.8 0.0 2.3e-17 64.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW76605.1 - 2.9e-13 49.5 0.0 1.5e-12 47.1 0.0 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW76606.1 - 1.1e-32 112.2 0.3 1.9e-32 111.5 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW76606.1 - 2.3e-20 73.7 0.0 4.2e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW76606.1 - 6.8e-13 48.3 0.1 1.6e-12 47.1 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EIW76606.1 - 0.011 15.3 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SIS_2 PF13580.1 EIW76606.1 - 0.03 14.0 0.1 0.092 12.4 0.0 1.8 1 1 1 2 2 2 0 SIS domain HTH_41 PF14502.1 EIW76608.1 - 0.0074 15.8 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain G-alpha PF00503.15 EIW76610.1 - 5.1e-117 390.8 0.0 6.1e-117 390.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIW76610.1 - 1.1e-11 44.3 0.2 4.3e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family DUF815 PF05673.8 EIW76610.1 - 0.0096 14.8 0.4 0.028 13.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_29 PF13555.1 EIW76610.1 - 0.029 13.8 0.0 0.076 12.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EIW76610.1 - 0.056 12.9 0.0 0.81 9.1 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 EIW76610.1 - 0.056 12.8 0.0 0.32 10.3 0.0 2.0 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EIW76610.1 - 0.077 12.1 0.0 2.1 7.4 0.0 2.2 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Ribosomal_L28 PF00830.14 EIW76611.1 - 0.064 13.0 1.1 0.1 12.4 0.7 1.4 1 0 0 1 1 1 0 Ribosomal L28 family RNA_pol_I_A49 PF06870.7 EIW76612.1 - 2.4e-84 283.1 1.0 2.7e-84 282.9 0.7 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor SET PF00856.23 EIW76613.1 - 2.1e-19 70.4 0.2 2.1e-19 70.4 0.2 3.5 2 2 0 2 2 2 1 SET domain SRI PF08236.6 EIW76613.1 - 7.1e-16 57.9 14.1 7.1e-16 57.9 9.8 2.2 3 0 0 3 3 3 1 SRI (Set2 Rpb1 interacting) domain Med26 PF08711.6 EIW76613.1 - 0.11 12.0 2.0 0.43 10.1 0.0 2.7 3 1 0 3 3 3 0 TFIIS helical bundle-like domain TCTP PF00838.12 EIW76613.1 - 7.8 6.4 16.2 0.34 10.8 2.3 2.7 2 1 1 3 3 3 0 Translationally controlled tumour protein Complex1_LYR PF05347.10 EIW76614.1 - 5.2e-10 38.9 0.1 9.1e-10 38.1 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EIW76614.1 - 6.2e-08 32.7 0.1 1.1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EIW76614.1 - 0.059 13.8 0.1 0.078 13.4 0.1 1.3 1 0 0 1 1 1 0 Complex1_LYR-like DPBB_1 PF03330.13 EIW76616.1 - 3.1e-11 43.1 0.1 4.8e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIW76616.1 - 0.0018 17.9 0.3 0.0021 17.6 0.2 1.2 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.7 EIW76616.1 - 0.003 17.5 0.2 0.0038 17.2 0.2 1.3 1 1 0 1 1 1 1 Cerato-platanin ADH_zinc_N PF00107.21 EIW76618.1 - 2.5e-29 101.4 0.2 3.7e-29 100.8 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW76618.1 - 1.9e-16 61.1 0.0 3.4e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW76618.1 - 1.7e-14 53.5 0.1 4.2e-14 52.2 0.1 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain HLH PF00010.21 EIW76619.1 - 1.4e-14 53.5 0.3 1.4e-14 53.5 0.2 1.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain Cortex-I_coil PF09304.5 EIW76619.1 - 0.058 13.4 3.6 0.091 12.8 2.3 1.7 1 1 0 1 1 1 0 Cortexillin I, coiled coil Angiomotin_C PF12240.3 EIW76619.1 - 7.7 5.9 8.8 8.3 5.8 3.4 2.4 1 1 2 3 3 3 0 Angiomotin C terminal Na_H_Exchanger PF00999.16 EIW76620.1 - 2.5e-67 227.0 35.2 3.4e-67 226.6 24.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Bap31 PF05529.7 EIW76621.1 - 1.1e-48 165.2 1.8 1.4e-48 164.9 1.2 1.1 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like AraC_N PF06719.8 EIW76621.1 - 0.011 14.9 0.1 0.34 10.2 0.1 2.1 2 0 0 2 2 2 0 AraC-type transcriptional regulator N-terminus Ribosomal_L29 PF00831.18 EIW76621.1 - 0.035 13.7 1.2 0.075 12.7 0.2 2.0 1 1 0 1 1 1 0 Ribosomal L29 protein DUF1361 PF07099.6 EIW76621.1 - 0.036 13.8 0.1 0.083 12.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1361) Cortexin PF11057.3 EIW76621.1 - 0.094 12.3 2.1 3.2 7.4 0.1 2.3 2 0 0 2 2 2 0 Cortexin of kidney Peptidase_S49_N PF08496.5 EIW76621.1 - 0.11 12.2 3.5 0.09 12.5 1.5 1.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal HALZ PF02183.13 EIW76621.1 - 0.32 10.7 7.1 0.075 12.7 1.1 2.4 3 0 0 3 3 3 0 Homeobox associated leucine zipper Fzo_mitofusin PF04799.8 EIW76621.1 - 0.39 10.0 2.7 0.68 9.2 1.9 1.3 1 0 0 1 1 1 0 fzo-like conserved region DUF2681 PF10883.3 EIW76621.1 - 2.5 8.3 6.7 13 6.0 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2681) UCH PF00443.24 EIW76622.1 - 3.4e-43 147.7 0.0 4.7e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW76622.1 - 3.5e-12 46.3 0.0 2.9e-11 43.3 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EIW76622.1 - 3.1e-05 23.2 0.0 6.3e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family RasGEF PF00617.14 EIW76623.1 - 8.9e-25 87.5 0.0 2.6e-24 85.9 0.0 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EIW76623.1 - 1.2e-09 38.2 0.8 2.7e-09 37.0 0.5 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif PP28 PF10252.4 EIW76624.1 - 2.3e-23 81.9 13.3 2.3e-23 81.9 9.2 3.0 2 1 1 3 3 3 2 Casein kinase substrate phosphoprotein PP28 Daxx PF03344.10 EIW76624.1 - 0.6 8.5 31.5 0.85 8.0 21.9 1.2 1 0 0 1 1 1 0 Daxx Family GH3 PF03321.8 EIW76626.1 - 2e-38 132.2 0.0 2.1e-38 132.1 0.0 1.0 1 0 0 1 1 1 1 GH3 auxin-responsive promoter GH3 PF03321.8 EIW76627.1 - 0.018 13.5 0.0 0.022 13.2 0.0 1.1 1 0 0 1 1 1 0 GH3 auxin-responsive promoter zf-primase PF09329.6 EIW76628.1 - 1.5e-14 53.3 1.3 2.6e-14 52.5 0.9 1.4 1 0 0 1 1 1 1 Primase zinc finger zf-H2C2_5 PF13909.1 EIW76630.1 - 0.12 12.5 1.9 0.26 11.5 0.6 2.1 2 0 0 2 2 2 0 C2H2-type zinc-finger domain PPR_2 PF13041.1 EIW76631.1 - 8.1e-05 22.5 0.0 3.8 7.5 0.0 4.6 5 0 0 5 5 5 2 PPR repeat family PPR_3 PF13812.1 EIW76631.1 - 0.00015 21.7 13.7 3.1 8.3 0.0 7.6 9 0 0 9 9 9 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 EIW76631.1 - 0.056 12.9 0.0 1.4 8.4 0.0 3.1 4 0 0 4 4 4 0 PPR repeat PPR PF01535.15 EIW76631.1 - 0.063 13.2 0.5 34 4.7 0.0 3.7 4 0 0 4 4 4 0 PPR repeat RRM_1 PF00076.17 EIW76632.1 - 4.6e-14 51.7 0.0 6.6e-14 51.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW76632.1 - 5.1e-10 39.1 0.0 7.4e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW76632.1 - 5.3e-07 29.3 0.0 7.8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIW76632.1 - 0.001 18.7 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF1777 PF08648.7 EIW76632.1 - 0.067 12.9 26.2 0.099 12.3 18.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Menin PF05053.8 EIW76632.1 - 2.4 6.1 6.8 2.9 5.9 4.7 1.0 1 0 0 1 1 1 0 Menin RINGv PF12906.2 EIW76633.1 - 1.3e-05 25.1 7.3 2.3e-05 24.3 5.1 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EIW76633.1 - 0.0028 17.4 6.7 0.0059 16.4 4.6 1.6 1 0 0 1 1 1 1 Ring finger domain FANCL_C PF11793.3 EIW76633.1 - 0.0053 16.6 3.1 0.0096 15.8 2.1 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.2 EIW76633.1 - 0.0056 16.7 5.0 0.011 15.7 3.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EIW76633.1 - 0.024 14.4 1.3 0.046 13.5 0.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EIW76633.1 - 2 8.5 4.8 6.8 6.8 3.4 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) eIF2_C PF09173.6 EIW76634.1 - 9.1e-36 121.7 0.3 2.1e-35 120.5 0.2 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.22 EIW76634.1 - 1.5e-35 122.3 0.0 2.6e-35 121.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 EIW76634.1 - 4.9e-12 45.7 1.0 9.3e-12 44.9 0.2 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Dak1_2 PF13684.1 EIW76634.1 - 0.071 12.0 0.4 0.11 11.4 0.2 1.2 1 0 0 1 1 1 0 Dihydroxyacetone kinase family GST_C PF00043.20 EIW76637.1 - 4.6e-10 39.3 0.0 8.2e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIW76637.1 - 3.8e-09 36.3 0.1 8.2e-09 35.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW76637.1 - 4.7e-09 36.2 0.0 1.1e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIW76637.1 - 6.2e-06 26.6 0.4 3.9e-05 24.0 0.3 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIW76637.1 - 2.5e-05 24.3 0.0 5.9e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain WYL PF13280.1 EIW76637.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 1 0 1 1 1 0 WYL domain 2OG-FeII_Oxy_2 PF13532.1 EIW76638.1 - 4e-15 56.1 0.0 5e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Zn_clus PF00172.13 EIW76639.1 - 1.1e-10 41.2 7.1 1.1e-10 41.2 4.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CENP-B_dimeris PF09026.5 EIW76641.1 - 0.049 13.8 3.4 0.072 13.3 2.4 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain LIN37 PF15306.1 EIW76641.1 - 0.12 12.3 0.5 0.16 11.9 0.4 1.1 1 0 0 1 1 1 0 LIN37 CcoS PF03597.10 EIW76641.1 - 0.32 10.4 1.8 0.54 9.7 1.3 1.3 1 0 0 1 1 1 0 Cytochrome oxidase maturation protein cbb3-type 60KD_IMP PF02096.15 EIW76642.1 - 9.1e-26 90.7 2.3 1.3e-25 90.2 1.6 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF202 PF02656.10 EIW76643.1 - 0.18 12.0 7.5 0.68 10.1 2.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF202) EF1_GNE PF00736.14 EIW76647.1 - 3.8e-31 106.6 2.5 8.7e-31 105.4 1.7 1.6 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EIW76647.1 - 1.4e-13 50.6 6.3 1.4e-13 50.6 4.4 2.6 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region GST_C_3 PF14497.1 EIW76647.1 - 0.0026 18.1 0.0 0.0057 17.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW76647.1 - 0.013 15.4 0.2 0.073 13.0 0.0 2.2 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIW76647.1 - 0.089 12.7 0.0 0.59 10.0 0.0 2.1 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain F-box-like PF12937.2 EIW76650.1 - 0.23 11.2 0.0 0.23 11.2 0.0 2.3 3 0 0 3 3 3 0 F-box-like WD40 PF00400.27 EIW76652.1 - 1.2e-11 44.0 14.0 0.0004 20.1 0.0 6.8 7 1 0 7 7 7 4 WD domain, G-beta repeat eIF2A PF08662.6 EIW76652.1 - 0.052 13.2 0.0 1.4 8.5 0.0 2.9 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.1 EIW76652.1 - 0.21 11.8 1.6 1.6 9.1 0.0 3.1 3 0 0 3 3 3 0 PQQ-like domain Pkinase PF00069.20 EIW76653.1 - 1.2e-44 152.3 0.0 1.8e-44 151.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW76653.1 - 3.7e-40 137.6 0.0 4.9e-40 137.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW76653.1 - 1.6e-05 24.7 0.0 3.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW76653.1 - 0.00064 18.7 0.0 0.00098 18.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EIW76653.1 - 0.019 13.8 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Fructosamin_kin PF03881.9 EIW76653.1 - 0.049 12.6 0.0 0.09 11.7 0.0 1.3 1 0 0 1 1 1 0 Fructosamine kinase DUF1365 PF07103.6 EIW76654.1 - 4.5e-19 68.4 0.1 1.4e-18 66.8 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1365) Pkinase PF00069.20 EIW76656.1 - 2.8e-42 144.6 0.0 4.3e-42 144.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW76656.1 - 1.7e-30 105.9 0.0 2.2e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW76656.1 - 5.4e-08 32.1 0.0 8.8e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW76656.1 - 0.005 16.6 0.5 0.015 15.0 0.2 1.9 1 1 2 3 3 3 1 Phosphotransferase enzyme family BP28CT PF08146.7 EIW76657.1 - 2.4e-25 89.0 0.6 1.1e-24 86.8 0.4 2.3 1 0 0 1 1 1 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EIW76657.1 - 2.8e-05 24.0 2.1 0.00018 21.4 0.2 3.3 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 10 Polyketide_cyc2 PF10604.4 EIW76660.1 - 9.2e-09 35.5 0.1 1.7e-08 34.7 0.1 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 EIW76660.1 - 8.5e-06 25.7 0.4 2.4e-05 24.3 0.3 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport PBD PF00786.23 EIW76662.1 - 0.00017 21.9 0.7 0.00035 20.9 0.5 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain SUI1 PF01253.17 EIW76663.1 - 3.6e-13 49.1 0.0 8.5e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 PUA PF01472.15 EIW76663.1 - 0.00031 20.4 0.1 0.00082 19.0 0.1 1.7 1 0 0 1 1 1 1 PUA domain Kin17_mid PF10357.4 EIW76663.1 - 0.0037 16.9 0.3 0.0069 16.0 0.2 1.3 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein SWIB PF02201.13 EIW76663.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 SWIB/MDM2 domain RrnaAD PF00398.15 EIW76664.1 - 4.1e-53 180.0 0.0 5.2e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EIW76664.1 - 2.8e-10 40.2 0.0 4.7e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW76664.1 - 2.9e-05 24.6 0.0 5.2e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW76664.1 - 4.2e-05 22.9 0.0 6.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.13 EIW76664.1 - 6.7e-05 22.1 0.0 0.0001 21.6 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.14 EIW76664.1 - 7.5e-05 22.3 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EIW76664.1 - 0.00017 21.3 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW76664.1 - 0.0011 18.5 0.0 0.0024 17.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EIW76664.1 - 0.0012 17.9 0.0 0.0023 17.0 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase UPF0020 PF01170.13 EIW76664.1 - 0.0055 16.3 0.0 0.2 11.1 0.0 2.3 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_12 PF08242.7 EIW76664.1 - 0.0084 16.5 0.0 0.018 15.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Pkinase PF00069.20 EIW76665.1 - 4.3e-20 71.9 0.3 2.7e-19 69.3 0.2 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW76665.1 - 1.9e-10 40.2 0.0 3.6e-10 39.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW76665.1 - 0.0015 18.3 0.1 0.002 17.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW76665.1 - 0.0047 15.9 0.2 0.023 13.6 0.1 1.8 1 1 0 1 1 1 1 Kinase-like MFS_1 PF07690.11 EIW76666.1 - 9.8e-24 83.7 20.7 5.7e-16 58.1 7.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIW76666.1 - 0.051 11.9 23.3 0.0053 15.2 5.3 3.5 3 1 1 4 4 4 0 MFS/sugar transport protein HSP70 PF00012.15 EIW76667.1 - 2.1e-264 878.0 6.7 2.3e-264 877.8 4.6 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIW76667.1 - 3.1e-18 65.4 1.0 2e-17 62.7 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 EIW76667.1 - 0.001 17.9 0.5 0.047 12.5 0.2 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 EIW76667.1 - 0.012 14.7 3.5 0.048 12.7 0.1 3.1 3 1 0 3 3 3 0 Hydantoinase/oxoprolinase Spectrin PF00435.16 EIW76667.1 - 0.42 10.9 7.8 3.8 7.8 0.3 3.5 2 2 1 3 3 3 0 Spectrin repeat FtsA PF14450.1 EIW76667.1 - 2.7 7.8 6.1 2.4e+02 1.5 4.2 3.7 1 1 0 1 1 1 0 Cell division protein FtsA AA_permease_2 PF13520.1 EIW76668.1 - 1.9e-61 207.8 57.4 2.3e-61 207.6 39.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIW76668.1 - 1.1e-16 60.2 50.7 1.7e-16 59.6 35.1 1.2 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 EIW76669.1 - 5.3e-22 78.0 30.7 3.5e-16 58.8 11.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Cellulase PF00150.13 EIW76670.1 - 5.6e-47 160.2 0.0 7.4e-47 159.8 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Pkinase PF00069.20 EIW76671.1 - 1e-51 175.5 0.0 1.4e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW76671.1 - 1.1e-26 93.4 0.0 1.7e-26 92.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW76671.1 - 3.8e-08 32.6 0.0 8.4e-07 28.2 0.0 2.2 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EIW76671.1 - 1.6e-06 28.0 0.1 0.0018 18.0 0.1 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EIW76671.1 - 0.002 17.5 0.0 0.0039 16.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EIW76671.1 - 0.024 13.6 0.0 0.055 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Acetyltransf_1 PF00583.19 EIW76672.1 - 4.9e-16 58.5 0.0 7.6e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EIW76672.1 - 2.3e-08 33.6 0.1 3.7e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EIW76672.1 - 1.4e-07 31.4 0.0 1.8e-07 31.1 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIW76672.1 - 1.7e-07 31.3 0.0 2.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIW76672.1 - 9.6e-07 28.8 0.0 1.8e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIW76672.1 - 2.6e-06 27.6 0.0 3.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIW76672.1 - 4.1e-05 23.4 0.0 8e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EIW76672.1 - 0.0061 16.1 0.2 0.0083 15.7 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIW76672.1 - 0.016 15.1 0.0 0.018 14.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EIW76672.1 - 0.065 13.1 0.1 0.16 11.9 0.0 1.6 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase DUF3414 PF11894.3 EIW76673.1 - 2.1e-263 876.9 0.0 2.7e-263 876.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) Got1 PF04178.7 EIW76674.1 - 3.9e-28 97.9 13.9 5.1e-28 97.5 9.6 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family FAD_binding_3 PF01494.14 EIW76675.1 - 3.2e-45 154.7 0.4 4.1e-28 98.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EIW76675.1 - 5.3e-07 28.8 2.4 0.0048 15.8 0.6 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIW76675.1 - 1.1e-06 28.8 0.2 2.8e-06 27.5 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIW76675.1 - 4.1e-05 22.8 0.3 5.9e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EIW76675.1 - 4.7e-05 22.0 0.7 0.16 10.3 0.4 2.1 2 0 0 2 2 2 2 HI0933-like protein Trp_halogenase PF04820.9 EIW76675.1 - 0.00091 17.9 0.6 0.26 9.8 0.0 2.1 1 1 0 2 2 2 2 Tryptophan halogenase ThiF PF00899.16 EIW76675.1 - 0.0015 18.3 0.2 0.0026 17.5 0.1 1.4 1 0 0 1 1 1 1 ThiF family FAD_binding_2 PF00890.19 EIW76675.1 - 0.0019 17.1 1.8 0.0029 16.5 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIW76675.1 - 0.0021 18.0 0.5 0.0094 15.8 0.5 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW76675.1 - 0.0048 16.8 0.3 0.011 15.7 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EIW76675.1 - 0.0079 15.9 0.2 0.085 12.6 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EIW76675.1 - 0.016 14.1 0.1 0.042 12.7 0.1 1.7 1 1 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 EIW76675.1 - 0.026 13.6 0.1 0.049 12.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family SE PF08491.5 EIW76675.1 - 0.053 12.3 0.0 0.077 11.8 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase Shikimate_DH PF01488.15 EIW76675.1 - 0.063 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EIW76675.1 - 0.35 9.6 1.7 0.85 8.4 0.3 2.1 3 0 0 3 3 3 0 Glucose inhibited division protein A MT-A70 PF05063.9 EIW76676.1 - 4e-39 133.9 0.0 1.4e-38 132.1 0.0 1.8 1 1 0 1 1 1 1 MT-A70 Noc2 PF03715.8 EIW76677.1 - 4.1e-98 327.9 0.0 4.2e-97 324.6 0.0 2.3 2 0 0 2 2 2 1 Noc2p family HSP70 PF00012.15 EIW76679.1 - 0.00044 18.2 0.0 0.0018 16.2 0.0 1.9 2 1 0 2 2 2 1 Hsp70 protein BcrAD_BadFG PF01869.15 EIW76679.1 - 0.052 12.8 0.0 0.084 12.1 0.0 1.3 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family MreB_Mbl PF06723.8 EIW76679.1 - 0.086 11.4 0.0 0.19 10.3 0.0 1.5 1 0 0 1 1 1 0 MreB/Mbl protein ALO PF04030.9 EIW76680.1 - 3.1e-82 276.0 0.4 3.8e-82 275.7 0.3 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EIW76680.1 - 8.1e-29 99.8 0.5 1.3e-28 99.1 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain RNA_pol_Rpb2_6 PF00562.23 EIW76681.1 - 2.2e-120 401.9 0.0 2.9e-120 401.5 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EIW76681.1 - 3.2e-57 192.7 0.0 2.4e-55 186.5 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EIW76681.1 - 4e-29 100.6 0.1 1.3e-28 99.0 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 EIW76681.1 - 8e-29 100.4 0.0 2.5e-28 98.7 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 EIW76681.1 - 3.3e-22 78.0 3.1 4.4e-22 77.6 1.3 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EIW76681.1 - 2.4e-21 75.2 0.4 6.5e-21 73.8 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EIW76681.1 - 1.3e-13 50.7 1.4 1.8e-13 50.2 0.1 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 Oxysterol_BP PF01237.13 EIW76682.1 - 2e-77 260.0 0.0 2.9e-77 259.5 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein DUF995 PF06191.7 EIW76682.1 - 0.1 12.0 1.1 0.25 10.7 0.1 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF995) Big_2 PF02368.13 EIW76682.1 - 0.13 12.2 2.6 3.3 7.6 0.2 2.7 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 2) UQ_con PF00179.21 EIW76683.1 - 2.1e-46 156.8 0.0 2.4e-46 156.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIW76683.1 - 0.0059 16.3 0.0 0.025 14.3 0.0 1.9 1 1 0 1 1 1 1 Prokaryotic E2 family B PseudoU_synth_1 PF01416.15 EIW76684.1 - 1.7e-26 92.6 0.0 2.5e-16 60.0 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase Peptidase_C65 PF10275.4 EIW76685.1 - 3.3e-61 206.7 0.0 3.9e-61 206.5 0.0 1.0 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.14 EIW76685.1 - 2e-05 25.1 0.0 0.00059 20.4 0.0 2.2 1 1 0 1 1 1 1 OTU-like cysteine protease SNF2_N PF00176.18 EIW76686.1 - 4.2e-43 147.2 0.0 7.7e-43 146.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW76686.1 - 1e-12 47.6 0.0 3.4e-09 36.4 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain VIGSSK PF14773.1 EIW76686.1 - 8.1e-06 25.6 0.1 1.9e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal ResIII PF04851.10 EIW76686.1 - 0.0001 22.2 0.0 0.069 12.9 0.0 2.7 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit DEAD PF00270.24 EIW76686.1 - 0.00081 18.9 0.0 0.013 14.9 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 EIW76686.1 - 0.03 13.1 0.0 0.092 11.5 0.0 1.6 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 HMG_box PF00505.14 EIW76687.1 - 8.2e-25 86.8 1.3 8.9e-25 86.7 0.9 1.0 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIW76687.1 - 2e-18 66.5 1.1 2.1e-18 66.4 0.8 1.0 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.7 EIW76687.1 - 0.00076 19.1 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 CHDNT (NUC034) domain HMG_box_5 PF14887.1 EIW76687.1 - 0.083 12.6 1.4 0.085 12.6 1.0 1.2 1 0 0 1 1 1 0 HMG (high mobility group) box 5 CENP-F_C_Rb_bdg PF10490.4 EIW76688.1 - 0.011 15.0 0.0 0.023 14.0 0.0 1.5 1 0 0 1 1 1 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 DUF1754 PF08555.5 EIW76688.1 - 0.2 12.2 4.0 0.29 11.7 2.8 1.2 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) tRNA-synt_1 PF00133.17 EIW76689.1 - 3.2e-38 131.1 0.0 8.7e-29 99.9 0.0 3.0 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EIW76689.1 - 6.2e-19 68.2 0.3 2.6e-18 66.2 0.0 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EIW76689.1 - 4.9e-17 61.6 0.0 8.6e-09 34.5 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EIW76689.1 - 1.8e-07 30.5 0.0 3.7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1_2 PF13603.1 EIW76689.1 - 0.14 11.4 1.3 3.3 6.9 0.0 3.3 4 0 0 4 4 4 0 Leucyl-tRNA synthetase, Domain 2 DEAD PF00270.24 EIW76690.1 - 1.8e-22 79.6 0.0 4.3e-22 78.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW76690.1 - 7.5e-17 60.9 0.0 2.7e-16 59.1 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RQC PF09382.5 EIW76690.1 - 9.6e-12 44.5 0.1 2.4e-11 43.2 0.0 1.7 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 EIW76690.1 - 3.6e-05 23.4 0.0 0.00011 21.8 0.0 1.8 1 1 0 1 1 1 1 HRDC domain ResIII PF04851.10 EIW76690.1 - 0.0074 16.1 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DPBB_1 PF03330.13 EIW76692.1 - 0.00013 21.9 2.1 0.00025 20.9 1.4 1.6 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Amidohydro_2 PF04909.9 EIW76693.1 - 2.4e-30 106.0 0.0 3e-30 105.7 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 EIW76693.1 - 3.2e-05 23.2 0.0 5.9e-05 22.3 0.0 1.5 2 0 0 2 2 2 1 TatD related DNase BolA PF01722.13 EIW76694.1 - 1.7e-16 59.9 0.1 2.1e-16 59.5 0.1 1.1 1 0 0 1 1 1 1 BolA-like protein DUF89 PF01937.14 EIW76695.1 - 8.1e-101 337.3 0.7 9.8e-101 337.0 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Amino_oxidase PF01593.19 EIW76696.1 - 4.4e-62 210.6 0.3 3.5e-50 171.3 0.0 2.1 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EIW76696.1 - 6.7e-10 38.8 0.3 1.8e-09 37.4 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIW76696.1 - 6.8e-07 29.5 1.3 0.00045 20.3 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW76696.1 - 0.00032 19.7 5.8 0.022 13.6 1.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW76696.1 - 0.00048 20.4 0.6 0.032 14.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIW76696.1 - 0.00061 18.9 1.7 0.00067 18.8 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 EIW76696.1 - 0.00087 18.2 0.2 0.0014 17.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EIW76696.1 - 0.0023 17.0 0.4 0.0077 15.3 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EIW76696.1 - 0.0032 16.0 0.4 0.03 12.7 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 EIW76696.1 - 0.006 16.3 1.6 0.21 11.3 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.17 EIW76696.1 - 0.0087 14.9 0.6 0.93 8.2 0.1 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EIW76696.1 - 0.023 13.6 0.2 1.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EIW76696.1 - 0.032 13.7 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 EIW76696.1 - 0.052 13.4 3.2 0.19 11.6 0.3 2.4 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EIW76696.1 - 0.067 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 4HBT PF03061.17 EIW76698.1 - 4.2e-06 26.7 0.3 0.011 15.8 0.0 2.7 2 1 0 2 2 2 2 Thioesterase superfamily Transp_cyt_pur PF02133.10 EIW76701.1 - 5.2e-107 358.1 34.7 5.9e-107 357.9 24.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Pkinase PF00069.20 EIW76702.1 - 0.00089 18.4 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EIW76702.1 - 0.0025 17.5 0.1 0.0074 16.0 0.1 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EIW76703.1 - 5.7e-07 28.9 0.0 9.8e-07 28.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EIW76703.1 - 4.7e-06 26.5 0.0 1.7e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIW76703.1 - 0.023 14.2 0.0 0.047 13.2 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EIW76703.1 - 0.079 12.3 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Glyco_hydro_2 PF00703.16 EIW76704.1 - 0.00033 21.0 0.1 0.0011 19.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Pkinase PF00069.20 EIW76705.1 - 4.9e-68 229.0 0.0 5.9e-68 228.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW76705.1 - 1.2e-41 142.5 0.0 1.5e-41 142.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW76705.1 - 9e-07 28.1 0.0 3.4e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIW76705.1 - 7.9e-05 22.5 0.8 0.026 14.2 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EIW76705.1 - 0.0017 17.4 0.0 0.0028 16.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EIW76705.1 - 0.16 10.7 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3729 PF12526.3 EIW76705.1 - 0.73 11.2 6.1 1.8 9.9 4.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3729) Pkinase PF00069.20 EIW76706.1 - 1.1e-51 175.4 0.0 1.6e-51 174.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW76706.1 - 6.2e-50 169.6 0.0 8.7e-50 169.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EIW76706.1 - 4.3e-06 26.3 4.7 8.3e-06 25.4 3.3 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Kdo PF06293.9 EIW76706.1 - 0.0064 15.5 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW76706.1 - 0.042 13.5 0.0 0.077 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW76706.1 - 0.24 10.3 0.0 0.36 9.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like PHD PF00628.24 EIW76706.1 - 0.92 9.2 7.1 1.9 8.2 4.9 1.5 1 0 0 1 1 1 0 PHD-finger Rap_GAP PF02145.10 EIW76707.1 - 3.1e-44 150.6 0.0 4.8e-39 133.6 0.0 2.2 2 0 0 2 2 2 2 Rap/ran-GAP Tuberin PF03542.11 EIW76707.1 - 6.5e-25 87.9 0.3 1.7e-24 86.5 0.1 1.7 2 0 0 2 2 2 1 Tuberin Apc1 PF12859.2 EIW76708.1 - 3.2e-10 40.1 0.0 1.2e-09 38.3 0.0 2.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EIW76708.1 - 0.063 13.5 11.6 1.4 9.2 0.0 5.5 5 0 0 5 5 5 0 Proteasome/cyclosome repeat DAHP_synth_1 PF00793.15 EIW76709.1 - 7.9e-96 319.9 0.0 9.6e-96 319.6 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family PIH1 PF08190.7 EIW76710.1 - 4.5e-25 88.7 0.1 1e-24 87.6 0.0 1.5 1 1 0 1 1 1 1 pre-RNA processing PIH1/Nop17 Chisel PF15355.1 EIW76710.1 - 0.031 14.2 0.6 0.06 13.3 0.4 1.5 1 0 0 1 1 1 0 Stretch-responsive small skeletal muscle X protein, Chisel DUF1319 PF07028.6 EIW76711.1 - 0.041 14.0 1.3 0.078 13.1 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) AP4E_app_platf PF14807.1 EIW76711.1 - 0.046 13.9 0.2 0.085 13.0 0.1 1.4 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform PAP_central PF04928.12 EIW76711.1 - 0.074 11.8 0.0 0.079 11.7 0.0 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain DUF3379 PF11859.3 EIW76711.1 - 0.28 10.3 4.7 0.31 10.1 1.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3379) DUF4502 PF14950.1 EIW76712.1 - 0.005 16.0 0.1 0.0073 15.5 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4502) VHS PF00790.14 EIW76713.1 - 1.2e-14 54.1 0.1 2.1e-14 53.3 0.1 1.3 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EIW76713.1 - 0.033 14.1 0.2 0.18 11.8 0.1 2.1 1 1 0 1 1 1 0 GAT domain RRM_1 PF00076.17 EIW76714.1 - 2.8e-36 122.9 0.1 1.1e-18 66.6 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW76714.1 - 9.3e-35 118.4 0.1 4.1e-20 71.5 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW76714.1 - 1e-12 47.7 0.1 4.2e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EIW76714.1 - 0.0016 17.8 1.3 0.53 9.8 0.1 2.3 2 0 0 2 2 2 2 Ribonuclease B OB domain Nup35_RRM_2 PF14605.1 EIW76714.1 - 0.014 15.1 0.0 2 8.2 0.0 2.3 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EIW76714.1 - 0.14 11.9 0.0 13 5.6 0.0 2.3 2 1 0 2 2 2 0 RNA binding motif COG7 PF10191.4 EIW76715.1 - 5.7e-74 249.4 0.0 1.8e-39 135.3 0.0 2.2 2 0 0 2 2 2 2 Golgi complex component 7 (COG7) DASH_Dad2 PF08654.5 EIW76715.1 - 0.17 11.9 0.4 28 4.7 0.1 3.3 3 0 0 3 3 3 0 DASH complex subunit Dad2 HNH_2 PF13391.1 EIW76716.1 - 1.6e-06 27.8 0.1 3.3e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease YonK PF09642.5 EIW76716.1 - 0.033 13.8 0.0 0.072 12.7 0.0 1.5 1 0 0 1 1 1 0 YonK protein DUF3632 PF12311.3 EIW76718.1 - 5.9e-37 127.2 7.3 5.9e-37 127.2 5.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3632) LIM PF00412.17 EIW76720.1 - 4.4e-24 84.3 19.3 2.6e-12 46.5 3.7 2.2 2 0 0 2 2 2 2 LIM domain Zn-ribbon_8 PF09723.5 EIW76720.1 - 0.0074 16.2 12.5 3.2 7.7 0.3 4.3 4 0 0 4 4 4 2 Zinc ribbon domain zf-ribbon_3 PF13248.1 EIW76720.1 - 0.078 12.2 16.6 1.4 8.2 0.3 4.5 4 0 0 4 4 4 0 zinc-ribbon domain YdjO PF14169.1 EIW76720.1 - 0.2 11.1 2.9 7.9 6.0 0.0 3.7 4 0 0 4 4 4 0 Cold-inducible protein YdjO Zn_Tnp_IS1595 PF12760.2 EIW76720.1 - 2 8.2 26.7 0.85 9.4 3.0 4.3 2 2 2 4 4 4 0 Transposase zinc-ribbon domain DUF2082 PF09855.4 EIW76720.1 - 3.6 7.4 6.5 0.46 10.3 0.2 2.6 3 0 0 3 3 3 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) DUF3039 PF11238.3 EIW76720.1 - 4.1 6.9 11.5 3 7.3 0.2 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3039) Cytochrom_c3_2 PF14537.1 EIW76720.1 - 5.5 7.4 11.5 5.3 7.4 2.8 2.4 2 0 0 2 2 2 0 Cytochrome c3 DUF2318 PF10080.4 EIW76720.1 - 8.7 6.1 10.5 3.6 7.4 0.5 3.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2318) eIF-5a PF01287.15 EIW76721.1 - 3.7e-27 94.0 0.1 5.6e-27 93.4 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EIW76721.1 - 3e-05 23.5 0.8 5.8e-05 22.6 0.6 1.5 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EIW76721.1 - 0.015 15.1 0.0 0.023 14.5 0.0 1.3 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain TcdB_toxin_midN PF12256.3 EIW76721.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region XPG_I PF00867.13 EIW76723.1 - 2e-18 66.2 0.0 3.7e-18 65.3 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EIW76723.1 - 0.0001 22.5 0.0 0.00032 20.9 0.0 1.8 1 1 0 1 1 1 1 XPG N-terminal domain zf-RanBP PF00641.13 EIW76724.1 - 0.00069 18.6 16.2 0.011 14.8 2.9 2.5 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others AAA_12 PF13087.1 EIW76725.1 - 1.4e-54 184.5 0.0 2.8e-54 183.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIW76725.1 - 1.2e-47 162.4 0.2 1.7e-47 161.9 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW76725.1 - 3.7e-12 45.8 0.1 2e-11 43.4 0.1 2.3 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EIW76725.1 - 1.6e-09 37.6 0.1 2e-05 24.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain UvrD-helicase PF00580.16 EIW76725.1 - 1.2e-06 28.0 0.1 2.8e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain Viral_helicase1 PF01443.13 EIW76725.1 - 0.0012 18.4 0.1 9.3 5.6 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 EIW76725.1 - 0.035 14.4 1.7 0.096 13.0 0.3 2.4 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 EIW76725.1 - 0.052 13.7 0.1 0.32 11.1 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EIW76725.1 - 0.14 11.4 0.0 0.33 10.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein CorA PF01544.13 EIW76725.1 - 0.23 10.4 1.2 0.35 9.8 0.8 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF2075 PF09848.4 EIW76725.1 - 0.59 9.0 1.8 1 8.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) SAP PF02037.22 EIW76726.1 - 0.0078 15.7 0.4 0.012 15.0 0.3 1.3 1 0 0 1 1 1 1 SAP domain Rho_N PF07498.7 EIW76726.1 - 0.044 13.5 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain CUE PF02845.11 EIW76727.1 - 2.6e-06 26.7 0.0 4.5e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 CUE domain Amidohydro_3 PF07969.6 EIW76728.1 - 2.2e-76 257.6 0.0 2.6e-76 257.4 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 EIW76728.1 - 2.1e-06 27.6 0.1 6.6e-05 22.7 0.0 2.6 3 0 0 3 3 3 1 Amidohydrolase family Amidohydro_4 PF13147.1 EIW76728.1 - 0.0071 16.4 0.9 1.1 9.2 0.0 3.2 3 1 0 3 3 3 1 Amidohydrolase TEP1_N PF05386.6 EIW76728.1 - 0.021 14.2 0.5 0.14 11.6 0.0 2.7 2 0 0 2 2 2 0 TEP1 N-terminal domain Amidohydro_5 PF13594.1 EIW76728.1 - 0.033 13.9 4.5 0.05 13.4 0.0 3.3 3 1 0 3 3 3 0 Amidohydrolase CTP_transf_2 PF01467.21 EIW76729.1 - 2.9e-17 63.1 0.0 4.3e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase SapA PF02199.10 EIW76729.1 - 0.046 13.4 0.3 0.078 12.7 0.2 1.3 1 0 0 1 1 1 0 Saposin A-type domain DUF4218 PF13960.1 EIW76732.1 - 4.7e-05 22.8 0.0 9.4e-05 21.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Striatin PF08232.7 EIW76734.1 - 0.014 15.7 1.1 0.014 15.7 0.7 3.2 4 1 0 4 4 4 0 Striatin family Cauli_VI PF01693.11 EIW76740.1 - 0.0011 18.9 0.2 0.0021 18.0 0.1 1.5 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF605 PF04652.11 EIW76740.1 - 0.33 10.3 8.6 0.43 9.9 5.9 1.1 1 0 0 1 1 1 0 Vta1 like Glycoprotein_G PF00802.14 EIW76741.1 - 0.75 8.8 6.7 0.62 9.1 0.1 2.3 2 0 0 2 2 2 0 Pneumovirus attachment glycoprotein G Trypan_PARP PF05887.6 EIW76742.1 - 1.1 9.0 6.1 1.4 8.6 4.2 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) RVT_3 PF13456.1 EIW76747.1 - 1.7e-06 27.7 0.1 2.3e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase-like Clr5 PF14420.1 EIW76752.1 - 0.038 13.8 0.2 0.089 12.6 0.1 1.5 1 0 0 1 1 1 0 Clr5 domain Stc1 PF12898.2 EIW76757.1 - 0.57 10.2 3.5 0.94 9.5 2.4 1.6 1 1 0 1 1 1 0 Stc1 domain RVT_1 PF00078.22 EIW76760.1 - 3.7e-08 32.9 0.0 4e-08 32.8 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Transposase_21 PF02992.9 EIW76764.1 - 0.00092 18.3 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DDE_3 PF13358.1 EIW76765.1 - 4.2e-08 33.0 0.0 5.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease HGD-D PF06050.8 EIW76765.1 - 0.015 14.1 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component Fijivirus_P9-2 PF06837.6 EIW76767.1 - 0.073 12.1 2.8 0.15 11.2 1.9 1.5 1 0 0 1 1 1 0 Fijivirus P9-2 protein Dimer_Tnp_hAT PF05699.9 EIW76768.1 - 8.3e-15 54.1 0.1 1.1e-14 53.8 0.1 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MS_channel PF00924.13 EIW76770.1 - 5 6.3 5.8 2.7 7.2 2.5 1.6 2 0 0 2 2 2 0 Mechanosensitive ion channel Syja_N PF02383.13 EIW76771.1 - 7.9e-88 294.2 0.0 1.4e-87 293.4 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain TFIIE_beta PF02186.10 EIW76772.1 - 0.00047 20.1 1.1 0.00074 19.4 0.2 1.8 2 0 0 2 2 2 1 TFIIE beta subunit core domain Pkinase PF00069.20 EIW76773.1 - 2.3e-08 33.4 0.0 4.9e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW76773.1 - 0.0014 17.8 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PAP_assoc PF03828.14 EIW76774.1 - 2e-15 56.4 0.6 4.1e-15 55.4 0.4 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EIW76774.1 - 2.6e-05 24.4 0.0 6.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_central PF04928.12 EIW76774.1 - 0.078 11.7 0.3 7.1 5.3 0.0 2.6 3 0 0 3 3 3 0 Poly(A) polymerase central domain LSM PF01423.17 EIW76775.1 - 2.3e-17 62.3 0.0 2.8e-17 62.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain HEAT_EZ PF13513.1 EIW76776.1 - 8.1e-20 70.7 4.6 5.9e-09 36.1 0.0 8.6 9 1 1 10 10 10 3 HEAT-like repeat HEAT_2 PF13646.1 EIW76776.1 - 8.4e-17 61.2 5.4 1.6e-06 28.3 0.0 7.6 2 1 5 7 7 7 3 HEAT repeats HEAT PF02985.17 EIW76776.1 - 9.3e-15 53.3 12.2 0.00022 21.0 0.0 10.0 12 0 0 12 12 12 3 HEAT repeat IBN_N PF03810.14 EIW76776.1 - 6.4e-13 48.4 0.1 3.5e-12 46.0 0.1 2.4 1 0 0 1 1 1 1 Importin-beta N-terminal domain Arm PF00514.18 EIW76776.1 - 1.1e-07 31.3 2.7 0.014 15.2 0.0 4.9 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.15 EIW76776.1 - 0.00011 20.7 1.0 0.78 7.9 0.0 3.8 2 1 1 3 3 3 2 Adaptin N terminal region CLASP_N PF12348.3 EIW76776.1 - 0.00074 18.9 0.2 0.39 10.0 0.1 4.2 2 2 2 4 4 4 1 CLASP N terminal DUF3385 PF11865.3 EIW76776.1 - 0.0047 16.8 0.1 8.9 6.2 0.0 4.2 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) MMS19_C PF12460.3 EIW76776.1 - 0.058 12.1 2.7 14 4.2 0.0 3.8 3 1 0 3 3 3 0 RNAPII transcription regulator C-terminal DUF3730 PF12530.3 EIW76776.1 - 0.13 12.1 1.9 6.9 6.5 0.0 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF3730) Lon_C PF05362.8 EIW76777.1 - 1.6e-65 220.2 0.1 2.6e-65 219.5 0.1 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 EIW76777.1 - 5.4e-22 78.3 0.0 1.6e-21 76.8 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) LON PF02190.11 EIW76777.1 - 6.5e-12 45.5 0.0 1.6e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 EIW76777.1 - 1.4e-10 41.0 0.0 3.9e-10 39.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EIW76777.1 - 1.3e-08 34.3 0.3 1e-07 31.5 0.0 2.4 2 1 0 2 2 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.9 EIW76777.1 - 2.2e-05 24.4 0.0 6.9e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EIW76777.1 - 0.00013 22.7 0.0 0.00083 20.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EIW76777.1 - 0.00056 20.0 0.9 0.045 13.8 0.0 3.3 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EIW76777.1 - 0.0011 18.8 0.0 0.0029 17.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW76777.1 - 0.0018 18.3 0.0 0.0018 18.3 0.0 3.5 2 2 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.7 EIW76777.1 - 0.0021 17.1 0.0 0.043 12.8 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EIW76777.1 - 0.0065 15.8 0.3 0.035 13.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EIW76777.1 - 0.015 14.9 0.0 0.04 13.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EIW76777.1 - 0.02 15.1 0.0 0.075 13.3 0.0 2.0 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EIW76777.1 - 0.037 13.7 0.0 0.079 12.6 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SKI PF01202.17 EIW76777.1 - 0.071 12.9 0.2 0.39 10.5 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase TIP49 PF06068.8 EIW76777.1 - 0.085 11.5 0.0 0.19 10.3 0.0 1.5 2 0 0 2 2 2 0 TIP49 C-terminus AAA_14 PF13173.1 EIW76777.1 - 0.093 12.6 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIW76777.1 - 0.16 12.2 0.7 1.3 9.3 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_24 PF13479.1 EIW76777.1 - 0.16 11.5 0.3 0.44 10.0 0.1 1.8 2 0 0 2 2 1 0 AAA domain RNA_helicase PF00910.17 EIW76777.1 - 0.19 11.9 0.0 0.46 10.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 EIW76777.1 - 0.21 11.3 0.1 0.21 11.3 0.1 2.8 4 0 0 4 4 2 0 Part of AAA domain DUF1160 PF06648.6 EIW76777.1 - 0.23 11.2 0.1 0.46 10.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1160) adh_short PF00106.20 EIW76779.1 - 1.8e-29 102.8 6.3 2.7e-29 102.2 4.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW76779.1 - 2e-25 89.9 1.1 2.7e-25 89.5 0.7 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW76779.1 - 1e-12 48.1 8.3 9.2e-12 44.9 5.7 2.0 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW76779.1 - 0.0066 15.9 1.6 0.014 14.8 1.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family OMPdecase PF00215.19 EIW76779.1 - 0.0075 15.6 0.6 0.039 13.3 0.0 2.2 1 1 1 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family NAD_binding_10 PF13460.1 EIW76779.1 - 0.028 14.4 5.2 0.1 12.5 3.6 2.3 1 1 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 EIW76779.1 - 0.059 12.0 0.3 0.093 11.4 0.1 1.5 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family S-AdoMet_synt_N PF00438.15 EIW76779.1 - 0.066 13.4 0.2 0.39 10.9 0.1 2.1 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, N-terminal domain Reo_sigmaC PF04582.7 EIW76780.1 - 7.8e-05 22.0 7.8 7.8e-05 22.0 5.4 4.8 2 1 2 5 5 5 2 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EIW76780.1 - 0.00016 21.5 57.6 0.16 11.8 1.4 6.0 2 1 2 4 4 4 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 EIW76780.1 - 0.0036 15.1 69.9 0.062 11.0 18.7 3.0 1 1 2 3 3 3 3 Myosin tail HALZ PF02183.13 EIW76780.1 - 0.0043 16.7 11.1 3.3 7.5 0.0 5.3 4 1 1 5 5 5 2 Homeobox associated leucine zipper BLOC1_2 PF10046.4 EIW76780.1 - 0.0046 17.0 11.4 1.1 9.4 0.0 4.8 3 2 2 5 5 5 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6 PF04111.7 EIW76780.1 - 0.11 11.5 50.1 0.19 10.7 2.7 4.4 1 1 2 4 4 4 0 Autophagy protein Apg6 GAS PF13851.1 EIW76780.1 - 0.18 10.9 41.5 0.61 9.2 2.2 5.0 2 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding Hemagglutinin PF00509.13 EIW76780.1 - 1.8 6.5 3.3 3.3 5.7 2.3 1.3 1 0 0 1 1 1 0 Haemagglutinin Erp_C PF06780.6 EIW76780.1 - 4.2 7.2 12.5 8.2 6.2 0.1 3.4 3 0 0 3 3 3 0 Erp protein C-terminus ATG16 PF08614.6 EIW76780.1 - 6 6.6 72.5 0.016 15.0 8.5 5.4 3 2 2 5 5 5 0 Autophagy protein 16 (ATG16) adh_short PF00106.20 EIW76784.1 - 1.2e-32 113.1 5.2 1.2e-32 113.1 3.6 1.3 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW76784.1 - 5e-19 69.0 0.4 6.1e-19 68.7 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW76784.1 - 3.6e-16 59.3 4.0 5.4e-16 58.7 2.8 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW76784.1 - 0.012 15.0 0.9 0.021 14.2 0.5 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW76784.1 - 0.013 15.5 3.0 0.032 14.2 2.1 1.8 1 1 0 1 1 1 0 NADH(P)-binding HAD PF12710.2 EIW76784.1 - 0.056 13.6 0.1 0.5 10.5 0.1 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase S-AdoMet_synt_N PF00438.15 EIW76784.1 - 0.13 12.5 0.1 0.76 10.0 0.1 2.2 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, N-terminal domain Retrotrans_gag PF03732.12 EIW76786.1 - 0.0033 17.4 0.1 0.24 11.4 0.0 2.3 2 0 0 2 2 2 1 Retrotransposon gag protein TMF_TATA_bd PF12325.3 EIW76786.1 - 0.065 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Med4 PF10018.4 EIW76786.1 - 0.14 11.5 3.3 1.7 7.9 0.0 2.5 3 0 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 Baculo_PEP_C PF04513.7 EIW76786.1 - 0.45 10.3 5.1 0.9 9.3 3.5 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.3 EIW76786.1 - 0.77 8.9 7.1 1.2 8.3 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-CCHC PF00098.18 EIW76786.1 - 4.5 7.3 7.5 12 6.0 2.2 2.7 2 1 0 2 2 2 0 Zinc knuckle eIF3g PF12353.3 EIW76787.1 - 0.016 15.0 0.0 0.034 14.0 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G UBN2_2 PF14227.1 EIW76788.1 - 4.7e-08 32.5 0.0 7e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIW76788.1 - 1.5e-05 24.7 0.0 2.5e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-SNAP50_C PF12251.3 EIW76788.1 - 0.012 15.0 0.1 0.025 13.9 0.1 1.4 1 1 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal DUF599 PF04654.7 EIW76788.1 - 0.036 13.2 0.0 0.051 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF599 ATG16 PF08614.6 EIW76789.1 - 1.7e-05 24.7 13.8 1.7e-05 24.7 9.6 5.1 3 2 2 5 5 4 2 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 EIW76789.1 - 2.5e-05 24.1 58.6 0.029 14.2 1.8 5.8 2 2 3 5 5 5 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EIW76789.1 - 0.00033 19.9 7.4 0.00033 19.9 5.1 4.2 1 1 3 5 5 5 1 Reovirus sigma C capsid protein HALZ PF02183.13 EIW76789.1 - 0.013 15.1 13.5 2.7 7.7 0.0 5.6 4 1 1 5 5 5 0 Homeobox associated leucine zipper GAS PF13851.1 EIW76789.1 - 0.021 14.0 43.2 0.1 11.7 2.4 4.9 2 1 1 4 4 4 0 Growth-arrest specific micro-tubule binding Myosin_tail_1 PF01576.14 EIW76789.1 - 0.056 11.1 73.2 0.076 10.7 21.4 3.0 1 1 2 3 3 3 0 Myosin tail APG6 PF04111.7 EIW76789.1 - 0.67 8.9 54.0 0.87 8.5 0.7 4.5 1 1 2 4 4 4 0 Autophagy protein Apg6 Hemagglutinin PF00509.13 EIW76789.1 - 1.4 6.9 3.5 2.6 6.0 2.5 1.3 1 0 0 1 1 1 0 Haemagglutinin Tropomyosin_1 PF12718.2 EIW76789.1 - 2.9 7.7 64.0 1.4 8.7 2.5 6.6 1 1 5 7 7 7 0 Tropomyosin like Bap31 PF05529.7 EIW76789.1 - 6.7 6.1 30.0 0.53 9.7 0.2 5.6 4 2 1 5 5 5 0 B-cell receptor-associated protein 31-like Erp_C PF06780.6 EIW76789.1 - 9 6.1 13.8 7.9 6.3 0.1 3.5 3 1 0 3 3 3 0 Erp protein C-terminus NPV_P10 PF05531.7 EIW76789.1 - 9.5 6.5 18.0 24 5.2 0.1 5.8 5 1 1 6 6 6 0 Nucleopolyhedrovirus P10 protein Peptidase_S32 PF05579.8 EIW76791.1 - 0.046 12.7 0.2 0.13 11.2 0.1 1.7 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Trypsin_2 PF13365.1 EIW76791.1 - 0.072 13.0 0.0 0.28 11.1 0.0 2.0 1 1 0 1 1 1 0 Trypsin-like peptidase domain AA_permease_2 PF13520.1 EIW76792.1 - 8.6e-15 54.1 10.9 3.2e-08 32.5 4.2 3.1 1 1 2 3 3 3 3 Amino acid permease Dimer_Tnp_hAT PF05699.9 EIW76793.1 - 1.9e-06 27.3 0.0 2e-06 27.3 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region LT-IIB PF06453.6 EIW76793.1 - 0.12 12.0 0.2 0.13 11.9 0.2 1.0 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) eIF-3c_N PF05470.7 EIW76795.1 - 0.11 10.5 3.4 0.15 10.1 2.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Sigma70_ner PF04546.8 EIW76795.1 - 1 8.9 8.5 2.3 7.7 5.9 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region AA_permease_2 PF13520.1 EIW76796.1 - 3.4e-53 180.7 40.4 4.2e-53 180.4 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIW76796.1 - 7.1e-17 60.9 35.3 1.2e-16 60.1 24.5 1.3 1 1 0 1 1 1 1 Amino acid permease PNRC PF15365.1 EIW76798.1 - 4.8 7.2 7.1 0.67 10.0 0.2 3.0 3 0 0 3 3 3 0 Proline-rich nuclear receptor coactivator Aldo_ket_red PF00248.16 EIW76799.1 - 2e-52 177.7 0.0 2.6e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.2 EIW76803.1 - 4.8e-05 22.9 1.1 0.00016 21.3 0.8 2.0 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EIW76803.1 - 0.0038 16.9 2.3 0.0072 16.0 0.4 2.4 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.2 EIW76803.1 - 0.041 13.5 1.6 0.44 10.2 0.3 2.9 1 1 0 2 2 2 0 Leucine Rich repeats (2 copies) AA_permease_2 PF13520.1 EIW76804.1 - 5.6e-55 186.6 39.5 6.8e-55 186.3 27.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIW76804.1 - 5.6e-18 64.5 34.4 7.8e-18 64.0 23.9 1.1 1 0 0 1 1 1 1 Amino acid permease DUF202 PF02656.10 EIW76806.1 - 0.14 12.3 0.1 0.18 12.0 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF202) DUF3481 PF11980.3 EIW76807.1 - 0.27 11.0 6.5 0.29 10.9 0.4 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF3481) Abhydrolase_3 PF07859.8 EIW76808.1 - 1.4e-18 67.2 0.0 1.9e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIW76808.1 - 3.5e-15 55.5 0.0 4.9e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) p450 PF00067.17 EIW76812.1 - 8.3e-70 235.5 0.0 1.3e-69 234.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_30 PF02055.11 EIW76813.1 - 6.5e-28 97.1 1.0 9.5e-28 96.6 0.7 1.2 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 p450 PF00067.17 EIW76814.1 - 6.6e-62 209.5 0.0 1e-61 208.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF1289 PF06945.8 EIW76815.1 - 0.0097 15.3 0.5 0.015 14.7 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) Glyco_hydro_30 PF02055.11 EIW76816.1 - 2.5e-26 91.9 1.5 5.6e-26 90.8 1.1 1.5 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EIW76816.1 - 0.026 13.4 0.0 0.89 8.4 0.0 2.1 2 0 0 2 2 2 0 O-Glycosyl hydrolase family 30 Glyco_hydro_30 PF02055.11 EIW76817.1 - 1.5e-24 86.0 0.4 2.4e-24 85.4 0.3 1.2 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 ArgK PF03308.11 EIW76818.1 - 0.18 10.5 0.0 0.29 9.8 0.0 1.2 1 0 0 1 1 1 0 ArgK protein DUF2721 PF11026.3 EIW76819.1 - 4.2 7.0 7.9 1.5 8.4 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2721) Membr_traf_MHD PF10540.4 EIW76820.1 - 5.3e-17 61.9 0.1 2.4e-16 59.7 0.1 2.3 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EIW76820.1 - 1.8e-06 27.7 0.0 3.9e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain YopH_N PF09013.5 EIW76820.1 - 0.07 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 YopH, N-terminal HSP70 PF00012.15 EIW76821.1 - 1.9e-75 254.0 4.7 1.9e-75 254.0 3.3 2.1 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EIW76821.1 - 0.00084 18.0 1.3 0.0017 17.0 0.2 1.9 2 0 0 2 2 2 1 MreB/Mbl protein Tub PF01167.13 EIW76821.1 - 0.078 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Tub family Trans_reg_C PF00486.23 EIW76821.1 - 0.12 12.3 0.1 0.63 9.9 0.0 2.2 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal NmrA PF05368.8 EIW76823.1 - 5.4e-07 29.1 0.0 9.2e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Gp_dh_C PF02800.15 EIW76824.1 - 4.6e-72 240.6 0.0 7e-72 240.0 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EIW76824.1 - 2e-60 203.1 0.1 3.2e-60 202.4 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EIW76824.1 - 0.0056 16.5 0.1 0.015 15.2 0.1 1.7 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 EIW76824.1 - 0.0097 15.0 0.0 0.021 13.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain p450 PF00067.17 EIW76825.1 - 8.6e-68 228.9 0.0 1.2e-67 228.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PPR_3 PF13812.1 EIW76827.1 - 2.2e-13 49.3 7.8 0.023 14.9 0.0 8.3 8 0 0 8 8 8 3 Pentatricopeptide repeat domain PPR PF01535.15 EIW76827.1 - 1.5e-11 43.4 3.4 0.021 14.7 0.1 6.6 6 1 0 6 6 6 3 PPR repeat PPR_2 PF13041.1 EIW76827.1 - 8.4e-09 35.2 0.8 0.033 14.1 0.0 6.5 6 1 1 7 7 7 2 PPR repeat family PPR_1 PF12854.2 EIW76827.1 - 3.7e-05 23.0 0.5 0.5 9.8 0.0 4.5 4 1 0 4 4 4 2 PPR repeat TPR_14 PF13428.1 EIW76827.1 - 0.00041 20.7 4.4 1.3 9.8 0.0 5.7 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIW76827.1 - 0.026 14.9 0.3 2.5 8.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_hydro_30 PF02055.11 EIW76828.1 - 1.5e-27 96.0 0.9 2e-27 95.5 0.6 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EIW76828.1 - 0.0062 15.5 0.0 0.091 11.6 0.0 2.1 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 MFS_1 PF07690.11 EIW76829.1 - 3e-23 82.1 36.0 5.4e-18 64.8 7.8 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily WBP-1 PF11669.3 EIW76829.1 - 6.8 6.8 6.5 6 7.0 0.4 3.0 2 1 1 3 3 3 0 WW domain-binding protein 1 Kelch_4 PF13418.1 EIW76831.1 - 1.8e-44 149.2 18.6 1.9e-10 40.3 0.2 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EIW76831.1 - 2.1e-38 129.6 16.3 1.8e-08 34.2 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EIW76831.1 - 9.5e-35 118.0 11.4 2.4e-07 30.5 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 EIW76831.1 - 4.2e-33 112.6 8.0 3.9e-06 26.3 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EIW76831.1 - 1.7e-29 100.7 12.0 7.8e-06 25.8 0.0 6.3 4 1 2 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EIW76831.1 - 1.4e-22 78.5 11.0 0.00013 21.5 0.5 6.3 6 0 0 6 6 6 5 Kelch motif MIP-T3 PF10243.4 EIW76831.1 - 0.5 8.7 16.7 0.64 8.4 11.6 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 EIW76831.1 - 2.2 7.9 31.2 3.4 7.3 21.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) PQQ_3 PF13570.1 EIW76831.1 - 2.5 8.5 10.8 19 5.6 0.0 4.5 6 0 0 6 6 6 0 PQQ-like domain SMP PF04927.7 EIW76835.1 - 2.9e-06 27.1 7.0 0.0067 16.3 0.3 3.5 3 1 0 3 3 3 2 Seed maturation protein DUF3123 PF11321.3 EIW76835.1 - 2.3 8.5 5.1 13 6.0 0.8 2.5 2 2 0 2 2 2 0 Protein of unknown function (DUF3123) SSF PF00474.12 EIW76837.1 - 1.4e-27 96.3 19.6 2.8e-27 95.4 13.6 1.4 1 0 0 1 1 1 1 Sodium:solute symporter family Pex24p PF06398.6 EIW76837.1 - 3.7 6.2 5.5 0.48 9.1 0.0 2.1 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Ish1 PF10281.4 EIW76838.1 - 1.5e-44 149.6 42.1 7e-08 32.3 3.4 8.3 8 0 0 8 8 8 6 Putative stress-responsive nuclear envelope protein HeH PF12949.2 EIW76838.1 - 1.1e-06 28.0 2.1 1.4 8.4 0.0 5.7 5 0 0 5 5 5 2 HeH/LEM domain Slx4 PF09494.5 EIW76838.1 - 0.0001 21.9 1.4 8.2 6.2 0.0 5.3 6 0 0 6 6 6 2 Slx4 endonuclease SAP PF02037.22 EIW76838.1 - 0.001 18.4 0.0 6.5 6.3 0.0 4.4 5 0 0 5 5 5 2 SAP domain Iron_traffic PF04362.9 EIW76838.1 - 0.0027 17.1 0.5 0.0083 15.5 0.0 2.2 1 1 0 1 1 1 1 Bacterial Fe(2+) trafficking APC2 PF08672.6 EIW76838.1 - 0.023 14.9 0.2 60 3.9 0.0 4.5 6 0 0 6 6 6 0 Anaphase promoting complex (APC) subunit 2 DUF883 PF05957.8 EIW76838.1 - 0.88 10.0 14.9 21 5.6 0.2 4.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF883) Ldh_1_N PF00056.18 EIW76839.1 - 3.1e-45 153.4 0.1 4.5e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EIW76839.1 - 1.3e-38 132.5 0.0 1.7e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EIW76839.1 - 0.0036 16.0 0.0 0.0048 15.6 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_30 PF02055.11 EIW76840.1 - 3.2e-13 48.7 0.2 4.9e-12 44.8 0.1 2.0 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 HNH_2 PF13391.1 EIW76842.1 - 0.0098 15.6 0.3 0.024 14.4 0.2 1.6 1 0 0 1 1 1 1 HNH endonuclease Adaptin_N PF01602.15 EIW76843.1 - 5.7e-150 500.1 6.2 7.2e-150 499.7 4.3 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EIW76843.1 - 1.4e-26 93.4 0.5 1.8e-23 83.3 0.0 3.3 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EIW76843.1 - 2e-19 69.6 2.7 3.1e-09 36.9 0.1 5.8 1 1 5 6 6 6 5 HEAT repeats HEAT PF02985.17 EIW76843.1 - 9.9e-06 25.2 15.5 0.0026 17.7 0.1 6.3 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.1 EIW76843.1 - 0.00024 21.4 14.7 0.023 15.1 0.2 6.9 8 1 1 9 9 9 1 HEAT-like repeat CLASP_N PF12348.3 EIW76843.1 - 0.0024 17.2 0.7 0.7 9.2 0.0 3.7 3 1 1 4 4 4 1 CLASP N terminal Cnd3 PF12719.2 EIW76843.1 - 0.0098 14.9 0.5 0.3 10.0 0.0 2.6 2 1 2 4 4 4 1 Nuclear condensing complex subunits, C-term domain Arm PF00514.18 EIW76843.1 - 0.0099 15.6 3.6 56 3.7 0.0 5.4 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Serglycin PF04360.7 EIW76843.1 - 0.11 12.2 0.5 0.26 11.0 0.3 1.7 1 0 0 1 1 1 0 Serglycin RNA_pol PF00940.14 EIW76844.1 - 3e-165 549.6 0.0 4.5e-165 549.0 0.0 1.3 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EIW76844.1 - 7.5e-73 245.5 0.1 1.2e-72 244.8 0.1 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal PPR_2 PF13041.1 EIW76844.1 - 0.00066 19.5 0.0 0.0022 17.9 0.0 1.9 2 0 0 2 2 2 1 PPR repeat family DUF859 PF05895.7 EIW76844.1 - 0.18 10.0 0.0 0.32 9.2 0.0 1.3 1 0 0 1 1 1 0 Siphovirus protein of unknown function (DUF859) HNH_2 PF13391.1 EIW76845.1 - 3.9e-06 26.5 0.0 6.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 HNH endonuclease DUF3638 PF12340.3 EIW76847.1 - 7.2e-79 263.9 0.3 1.4e-78 263.0 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EIW76847.1 - 1.8e-16 58.9 0.1 3.9e-16 57.8 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) FliT PF05400.8 EIW76848.1 - 0.0016 18.8 0.3 0.044 14.2 0.0 2.3 2 0 0 2 2 2 1 Flagellar protein FliT ATP_sub_h PF10775.4 EIW76849.1 - 8.2e-25 86.3 2.3 1.3e-24 85.6 1.6 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EIW76849.1 - 0.04 13.8 0.0 0.057 13.3 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 IATP PF04568.7 EIW76850.1 - 3.5e-11 42.9 0.7 4.1e-11 42.7 0.5 1.2 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP Bap31 PF05529.7 EIW76850.1 - 0.052 13.0 2.7 0.053 12.9 1.9 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like cIII PF08134.6 EIW76850.1 - 0.26 10.9 1.7 0.49 10.0 1.2 1.4 1 0 0 1 1 1 0 cIII protein family SUR7 PF06687.7 EIW76851.1 - 2.5e-17 63.1 18.0 1.3e-16 60.7 12.3 2.1 1 1 0 1 1 1 1 SUR7/PalI family MCR_beta PF02241.13 EIW76851.1 - 0.053 12.7 0.1 0.073 12.2 0.0 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain DUF4212 PF13937.1 EIW76851.1 - 0.31 11.0 5.3 0.78 9.7 2.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) DUF4293 PF14126.1 EIW76851.1 - 0.51 10.2 8.5 0.3 11.0 3.3 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) Amastin PF07344.6 EIW76851.1 - 5.1 6.7 14.2 0.35 10.4 5.4 2.1 1 1 1 2 2 2 0 Amastin surface glycoprotein Phage_holin_1 PF04531.8 EIW76851.1 - 6.6 6.8 6.4 20 5.3 0.0 2.9 3 0 0 3 3 3 0 Bacteriophage holin HNH_2 PF13391.1 EIW76852.1 - 7.8e-10 38.4 0.1 1.4e-09 37.5 0.1 1.5 1 0 0 1 1 1 1 HNH endonuclease Histone PF00125.19 EIW76854.1 - 1.2e-22 79.8 0.2 1.2e-22 79.8 0.1 1.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIW76854.1 - 0.0027 17.7 0.0 0.0044 17.0 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CsbD PF05532.7 EIW76855.1 - 0.0094 15.6 8.9 0.016 14.8 6.2 1.4 1 0 0 1 1 1 1 CsbD-like Mito_carr PF00153.22 EIW76856.1 - 4.3e-69 228.2 3.9 1.2e-22 79.4 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 EIW76856.1 - 0.0086 16.1 4.0 1.5 8.9 0.0 3.8 3 2 1 4 4 4 2 Tim17/Tim22/Tim23/Pmp24 family DUF3638 PF12340.3 EIW76857.1 - 4e-77 258.2 1.4 1.5e-76 256.4 0.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EIW76857.1 - 1.6e-17 62.2 0.1 4e-17 61.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) DUF3638 PF12340.3 EIW76859.1 - 7.6e-79 263.9 1.1 7.6e-79 263.9 0.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EIW76859.1 - 6.4e-17 60.3 0.1 1.4e-16 59.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) DUF3638 PF12340.3 EIW76860.1 - 4e-79 264.8 0.2 8.9e-79 263.6 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EIW76860.1 - 7.3e-18 63.4 0.1 1.4e-17 62.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) DUF947 PF06102.7 EIW76860.1 - 2.3 8.0 7.0 1.2e+02 2.3 4.9 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF947) U79_P34 PF03064.11 EIW76860.1 - 3.9 6.9 7.5 8.8 5.7 5.2 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 HEM4 PF02602.10 EIW76862.1 - 1.3e-31 109.6 0.0 1.5e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD SKN1 PF03935.10 EIW76863.1 - 3.4e-182 606.0 0.0 3.9e-182 605.8 0.0 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) GST_N PF02798.15 EIW76864.1 - 5e-12 45.8 0.0 9.2e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW76864.1 - 2.8e-10 40.0 0.0 5.8e-10 39.0 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIW76864.1 - 5.6e-07 29.6 0.0 9.6e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW76864.1 - 2.6e-06 27.2 0.0 3.9e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW76864.1 - 1.3e-05 25.5 0.0 2.1e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW76864.1 - 0.056 13.4 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain WD40 PF00400.27 EIW76866.1 - 7.6e-117 377.5 36.4 1.8e-11 43.4 0.1 14.4 14 0 0 14 14 14 14 WD domain, G-beta repeat eIF2A PF08662.6 EIW76866.1 - 3.2e-13 49.8 0.0 0.027 14.1 0.0 6.3 3 2 4 7 7 7 6 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EIW76866.1 - 9.9e-05 21.5 3.7 1.9 7.5 0.0 6.3 2 2 4 7 7 7 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 EIW76866.1 - 0.00028 20.4 16.7 2.9 7.6 0.0 10.0 13 0 0 13 13 13 1 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EIW76866.1 - 0.034 12.3 6.7 20 3.1 0.0 5.0 4 2 1 6 6 6 0 Nucleoporin Nup120/160 IKI3 PF04762.7 EIW76866.1 - 0.12 10.1 0.5 13 3.4 0.0 3.9 3 2 1 4 4 4 0 IKI3 family TFIIIC_delta PF12657.2 EIW76866.1 - 0.18 11.5 1.5 28 4.3 0.0 4.2 4 1 1 5 5 5 0 Transcription factor IIIC subunit delta N-term SET PF00856.23 EIW76867.1 - 0.0016 18.7 0.0 0.0058 16.9 0.0 1.8 1 1 0 1 1 1 1 SET domain Alpha-L-AF_C PF06964.7 EIW76868.1 - 5.9e-37 127.1 2.3 5.9e-37 127.1 1.6 1.9 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminus CBM_6 PF03422.10 EIW76868.1 - 0.018 15.1 1.9 0.018 15.1 1.3 2.3 3 0 0 3 3 3 0 Carbohydrate binding module (family 6) Terpene_synth_C PF03936.11 EIW76869.1 - 9.1e-19 67.7 0.0 1.2e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.6 EIW76869.1 - 0.027 13.1 0.0 0.034 12.7 0.0 1.2 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) zf-C2H2 PF00096.21 EIW76871.1 - 0.026 14.8 4.7 0.05 13.9 0.3 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW76871.1 - 9 6.8 7.9 2.4 8.6 0.1 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Baculo_PEP_C PF04513.7 EIW76873.1 - 0.043 13.6 0.4 0.18 11.6 0.2 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4404 PF14357.1 EIW76873.1 - 0.063 13.7 0.1 0.32 11.4 0.0 2.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) DUF4140 PF13600.1 EIW76873.1 - 0.56 10.6 3.1 1.6 9.1 0.4 2.3 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Pro_CA PF00484.14 EIW76874.1 - 2.7e-40 137.8 0.0 3.2e-40 137.6 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase WD40 PF00400.27 EIW76875.1 - 1.7e-08 34.0 3.2 0.0023 17.7 0.0 2.8 3 0 0 3 3 3 2 WD domain, G-beta repeat PD40 PF07676.7 EIW76875.1 - 0.003 17.1 0.4 0.77 9.4 0.0 2.3 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EIW76875.1 - 0.019 14.6 0.0 0.44 10.2 0.0 1.8 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EIW76877.1 - 4.4e-108 349.7 35.9 7.2e-12 44.7 0.2 13.4 13 0 0 13 13 13 13 WD domain, G-beta repeat eIF2A PF08662.6 EIW76877.1 - 3.7e-13 49.6 0.0 0.0058 16.3 0.0 5.6 2 2 4 6 6 6 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EIW76877.1 - 7.8e-08 31.8 8.3 6.6 6.5 0.0 8.9 9 0 0 9 9 9 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EIW76877.1 - 0.00026 19.2 1.7 3 5.8 0.0 5.4 6 3 1 7 7 7 2 Nucleoporin Nup120/160 IKI3 PF04762.7 EIW76877.1 - 0.016 13.0 0.1 0.12 10.1 0.0 2.5 2 1 1 3 3 3 0 IKI3 family Nbas_N PF15492.1 EIW76877.1 - 0.023 13.8 1.2 20 4.1 0.0 5.1 4 2 0 5 5 5 0 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 EIW76877.1 - 0.024 13.9 8.8 18 4.7 0.0 6.2 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature Nucleoporin_N PF08801.6 EIW76877.1 - 0.067 11.9 0.1 11 4.6 0.0 3.0 3 1 0 3 3 3 0 Nup133 N terminal like Peptidase_S9_N PF02897.10 EIW76877.1 - 0.14 10.6 0.0 2.4 6.6 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain NAD_binding_4 PF07993.7 EIW76878.1 - 1.4e-30 106.0 0.0 2.4e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EIW76878.1 - 7.1e-29 100.4 0.0 2.4e-26 92.0 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.16 EIW76878.1 - 7.8e-06 25.4 0.0 1.4e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW76878.1 - 1e-05 25.6 0.0 0.00012 22.1 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EIW76878.1 - 3.3e-05 23.8 0.3 0.00038 20.4 0.2 2.5 1 1 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 EIW76878.1 - 0.0013 18.9 0.0 0.017 15.3 0.0 2.4 1 1 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.5 EIW76878.1 - 0.003 17.2 0.0 0.02 14.5 0.0 2.1 1 1 0 1 1 1 1 KR domain ADH_N PF08240.7 EIW76879.1 - 7.3e-24 83.6 1.2 1.7e-23 82.4 0.8 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW76879.1 - 6.4e-15 54.8 0.0 1.2e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIW76879.1 - 6.9e-05 22.0 0.1 0.00011 21.3 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EIW76879.1 - 0.00085 18.9 0.1 0.0015 18.1 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.10 EIW76879.1 - 0.0032 17.3 0.0 0.0058 16.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EIW76879.1 - 0.0093 15.6 0.1 0.014 15.1 0.1 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 EIW76879.1 - 0.072 12.9 0.5 0.13 12.0 0.3 1.4 1 0 0 1 1 1 0 ThiF family SNARE_assoc PF09335.6 EIW76880.1 - 2.9e-16 59.7 10.9 3.6e-16 59.4 5.3 2.2 2 0 0 2 2 2 1 SNARE associated Golgi protein CoatB PF10389.4 EIW76880.1 - 0.036 13.9 8.1 0.44 10.4 0.1 2.5 2 0 0 2 2 2 0 Bacteriophage coat protein B DUF2976 PF11190.3 EIW76880.1 - 0.16 11.5 4.6 7.7 6.1 0.3 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2976) Lipase_GDSL_2 PF13472.1 EIW76881.1 - 2.4e-11 44.0 0.2 4.4e-11 43.2 0.2 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EIW76881.1 - 1.1e-06 28.6 0.4 9.7e-06 25.5 0.3 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AMP-binding PF00501.23 EIW76882.1 - 2e-84 283.4 0.1 3.2e-84 282.7 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Ras PF00071.17 EIW76883.1 - 1.4e-49 167.6 0.0 1.6e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW76883.1 - 2.4e-18 66.7 0.0 3.5e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW76883.1 - 2.9e-06 26.6 0.0 4.6e-06 25.9 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EIW76883.1 - 0.013 14.7 0.0 0.018 14.2 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RseC_MucC PF04246.7 EIW76885.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.4 1 1 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC AMP-binding PF00501.23 EIW76887.1 - 1.3e-33 116.0 0.0 2.5e-31 108.5 0.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EIW76887.1 - 4e-28 98.0 0.0 8.4e-28 96.9 0.0 1.5 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 EIW76887.1 - 0.0038 16.6 0.0 0.0071 15.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EIW76887.1 - 0.076 13.2 0.0 0.42 10.8 0.0 2.2 1 1 0 1 1 1 0 Phosphopantetheine attachment site TIR PF01582.15 EIW76887.1 - 0.3 10.5 0.0 0.59 9.5 0.0 1.5 1 0 0 1 1 1 0 TIR domain Polysacc_synt_2 PF02719.10 EIW76887.1 - 0.3 9.9 0.0 0.49 9.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein WD40 PF00400.27 EIW76888.1 - 2.2e-89 290.4 47.2 2.1e-12 46.3 0.4 12.1 12 0 0 12 12 12 12 WD domain, G-beta repeat eIF2A PF08662.6 EIW76888.1 - 8.5e-12 45.1 0.1 0.00081 19.1 0.0 6.1 2 2 3 6 6 6 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EIW76888.1 - 2.2e-08 33.5 9.8 0.5 10.0 0.0 8.9 10 0 0 10 10 10 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EIW76888.1 - 7e-05 22.0 1.5 13 4.7 0.0 6.3 3 2 4 7 7 7 0 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 EIW76888.1 - 0.00021 20.8 5.9 0.38 10.1 0.4 4.0 4 0 0 4 4 4 2 PQQ-like domain IKI3 PF04762.7 EIW76888.1 - 0.0032 15.3 2.7 0.023 12.5 0.0 3.2 4 1 1 5 5 5 1 IKI3 family Nup160 PF11715.3 EIW76888.1 - 0.0095 14.1 11.2 0.15 10.1 0.6 4.9 3 1 2 5 5 5 2 Nucleoporin Nup120/160 TruB_C PF09142.6 EIW76888.1 - 0.016 14.8 0.5 5.9 6.6 0.0 4.1 4 0 0 4 4 4 0 tRNA Pseudouridine synthase II, C terminal Nucleoporin_N PF08801.6 EIW76888.1 - 0.025 13.3 0.4 1.1 7.9 0.1 3.2 3 2 1 4 4 4 0 Nup133 N terminal like Hira PF07569.6 EIW76888.1 - 0.032 13.4 0.0 0.38 9.9 0.0 2.7 3 0 0 3 3 3 0 TUP1-like enhancer of split DUF3312 PF11768.3 EIW76888.1 - 0.2 9.8 0.0 21 3.1 0.0 3.4 3 2 2 5 5 5 0 Protein of unknown function (DUF3312) TFIIIC_delta PF12657.2 EIW76888.1 - 3.2 7.4 11.7 7.1 6.3 0.2 4.7 4 3 1 5 5 5 0 Transcription factor IIIC subunit delta N-term Peptidase_S9 PF00326.16 EIW76889.1 - 2e-37 128.4 0.0 2.9e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EIW76889.1 - 1.4e-09 38.1 0.1 5.7e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW76889.1 - 1.2e-08 34.8 0.0 2.2e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EIW76889.1 - 3e-05 23.7 0.0 5.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EIW76889.1 - 7.1e-05 22.4 0.0 0.00014 21.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 EIW76889.1 - 0.0088 15.3 0.0 0.017 14.3 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S28 PF05577.7 EIW76889.1 - 0.028 12.9 0.0 0.047 12.2 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 LIP PF03583.9 EIW76889.1 - 0.047 12.8 0.1 0.08 12.1 0.1 1.3 1 0 0 1 1 1 0 Secretory lipase PhoPQ_related PF10142.4 EIW76889.1 - 0.069 11.6 0.0 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein NfeD PF01957.13 EIW76890.1 - 0.033 14.3 0.5 0.033 14.3 0.4 2.7 2 1 2 4 4 4 0 NfeD-like C-terminal, partner-binding DUF106 PF01956.11 EIW76890.1 - 0.83 9.1 4.5 1.7 8.1 0.1 2.6 2 0 0 2 2 2 0 Integral membrane protein DUF106 Aminotran_1_2 PF00155.16 EIW76891.1 - 4e-36 124.7 0.0 4.9e-36 124.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIW76891.1 - 0.0083 15.2 0.0 0.017 14.2 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EIW76892.1 - 4e-40 137.8 0.0 4.6e-40 137.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIW76892.1 - 0.011 14.8 0.0 0.031 13.4 0.0 1.7 2 0 0 2 2 2 0 Beta-eliminating lyase WD40 PF00400.27 EIW76893.1 - 1.3e-92 300.7 24.4 1.3e-13 50.2 0.2 11.2 11 0 0 11 11 11 11 WD domain, G-beta repeat eIF2A PF08662.6 EIW76893.1 - 3e-13 49.9 0.0 9.6e-05 22.1 0.0 4.3 2 2 3 5 5 5 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EIW76893.1 - 2.2e-06 26.7 3.0 0.6 8.8 0.0 5.4 1 1 2 4 4 4 2 Nup133 N terminal like PQQ_3 PF13570.1 EIW76893.1 - 2.4e-06 27.6 5.9 7.1 7.0 0.0 6.8 6 2 0 6 6 6 1 PQQ-like domain PD40 PF07676.7 EIW76893.1 - 1.4e-05 24.6 6.1 27 4.5 0.0 8.4 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EIW76893.1 - 0.00013 20.2 10.2 0.93 7.5 0.0 5.8 2 2 3 6 6 6 3 Nucleoporin Nup120/160 Nbas_N PF15492.1 EIW76893.1 - 0.00024 20.2 2.2 3.5 6.6 0.0 5.9 3 3 5 8 8 8 1 Neuroblastoma-amplified sequence, N terminal BBS2_Mid PF14783.1 EIW76893.1 - 0.00031 20.4 0.3 0.07 12.9 0.0 4.2 5 1 0 5 5 5 1 Ciliary BBSome complex subunit 2, middle region IKI3 PF04762.7 EIW76893.1 - 0.0014 16.5 0.4 0.85 7.3 0.0 3.1 1 1 2 3 3 3 2 IKI3 family Me-amine-dh_H PF06433.6 EIW76893.1 - 0.0036 15.9 0.0 0.047 12.3 0.0 2.6 4 0 0 4 4 4 1 Methylamine dehydrogenase heavy chain (MADH) Peptidase_S9_N PF02897.10 EIW76893.1 - 0.012 14.1 0.2 0.08 11.5 0.0 2.4 2 1 0 2 2 2 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Proteasome_A_N PF10584.4 EIW76893.1 - 0.08 12.2 1.3 19 4.7 0.0 3.7 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Aminotran_1_2 PF00155.16 EIW76894.1 - 4.6e-24 85.0 0.0 2.8e-18 65.9 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class I and II NAD_binding_4 PF07993.7 EIW76897.1 - 1.5e-28 99.3 0.0 2.8e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EIW76897.1 - 2.2e-28 98.8 0.2 4.8e-26 91.1 0.2 2.4 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EIW76897.1 - 6e-06 25.8 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW76897.1 - 0.00068 19.6 0.0 0.01 15.8 0.0 2.5 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EIW76897.1 - 0.01 15.5 0.1 0.05 13.2 0.1 2.2 1 1 0 1 1 1 0 KR domain adh_short PF00106.20 EIW76897.1 - 0.016 15.1 2.3 0.034 14.0 0.1 2.6 2 1 0 2 2 2 0 short chain dehydrogenase PP-binding PF00550.20 EIW76897.1 - 0.085 13.1 0.0 0.78 10.0 0.0 2.3 1 1 0 1 1 1 0 Phosphopantetheine attachment site Semialdhyde_dh PF01118.19 EIW76897.1 - 0.089 13.1 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ACPS PF01648.15 EIW76898.1 - 0.0022 17.7 0.0 0.0036 17.1 0.0 1.4 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily NUDIX PF00293.23 EIW76899.1 - 2.6e-11 43.3 0.1 5.9e-11 42.1 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain Presenilin PF01080.12 EIW76899.1 - 0.0088 14.9 0.1 0.012 14.4 0.1 1.1 1 0 0 1 1 1 1 Presenilin SR-25 PF10500.4 EIW76899.1 - 0.011 15.2 0.5 0.011 15.2 0.4 2.0 3 0 0 3 3 3 0 Nuclear RNA-splicing-associated protein ABM PF03992.11 EIW76900.1 - 0.0012 18.7 1.6 0.034 14.1 0.1 3.1 2 1 0 3 3 3 2 Antibiotic biosynthesis monooxygenase ABM PF03992.11 EIW76901.1 - 0.064 13.2 0.1 3.3 7.7 0.0 2.4 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase DUF2098 PF09871.4 EIW76903.1 - 0.11 12.4 0.1 0.23 11.4 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) ACOX PF01756.14 EIW76904.1 - 3.1e-24 85.3 0.0 5.3e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EIW76904.1 - 1e-14 54.8 0.0 2e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EIW76904.1 - 3e-10 39.4 0.6 9.6e-09 34.6 0.1 2.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EIW76904.1 - 0.015 15.3 2.2 0.017 15.2 0.3 2.0 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain FAD_binding_5 PF00941.16 EIW76904.1 - 0.071 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain in molybdopterin dehydrogenase UPF0253 PF06786.7 EIW76904.1 - 0.16 12.0 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0253) La PF05383.12 EIW76906.1 - 4e-17 61.7 0.0 7.7e-17 60.8 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_3 PF08777.6 EIW76906.1 - 1.4e-06 28.1 1.3 4.6e-06 26.4 0.3 2.2 2 0 0 2 2 2 1 RNA binding motif RRM_1 PF00076.17 EIW76906.1 - 2.5e-05 23.8 0.5 6.4e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW76906.1 - 0.0005 19.9 0.0 0.0011 18.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) eIF-3_zeta PF05091.7 EIW76906.1 - 0.0044 15.7 0.1 0.0072 14.9 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) API5 PF05918.6 EIW76906.1 - 6.3 5.1 12.4 9.6 4.5 8.6 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) WD40 PF00400.27 EIW76907.1 - 8.5e-114 367.8 43.0 8.5e-12 44.4 0.9 12.2 12 0 0 12 12 12 12 WD domain, G-beta repeat eIF2A PF08662.6 EIW76907.1 - 1.4e-15 57.5 0.0 0.002 17.8 0.0 6.3 2 2 5 7 7 7 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EIW76907.1 - 9.6e-10 37.9 19.5 0.49 10.1 0.1 9.5 11 0 0 11 11 11 4 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EIW76907.1 - 6e-09 35.3 2.5 0.63 9.0 0.0 7.7 4 3 5 9 9 9 3 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.4 EIW76907.1 - 3.6e-07 29.8 2.3 0.0032 16.9 0.1 3.7 2 1 0 3 3 3 2 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.3 EIW76907.1 - 6.5e-05 21.2 11.1 1 7.3 0.0 6.2 3 2 3 6 6 6 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIW76907.1 - 0.00016 20.5 0.6 0.14 10.8 0.0 3.4 1 1 1 2 2 2 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 EIW76907.1 - 0.00017 20.0 0.1 1.7 6.8 0.0 3.9 1 1 3 4 4 4 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 EIW76907.1 - 0.003 17.0 6.0 1.3 8.4 0.1 4.1 3 2 0 4 4 4 2 PQQ-like domain Proteasome_A_N PF10584.4 EIW76907.1 - 0.5 9.7 10.7 92 2.4 0.0 6.7 8 0 0 8 8 8 0 Proteasome subunit A N-terminal signature GMC_oxred_N PF00732.14 EIW76908.1 - 3.7e-59 200.3 0.3 5.5e-59 199.7 0.2 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIW76908.1 - 3.8e-30 105.0 0.0 6.9e-30 104.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DUF4248 PF14053.1 EIW76908.1 - 0.11 12.0 0.2 0.8 9.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) Aconitase PF00330.15 EIW76909.1 - 9.9e-178 591.3 0.3 1.5e-177 590.8 0.2 1.2 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EIW76909.1 - 1.6e-45 154.4 0.0 2.9e-45 153.5 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Xpo1 PF08389.7 EIW76910.1 - 1.7e-06 28.0 0.0 2.3e-05 24.3 0.0 2.8 3 1 1 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 EIW76910.1 - 0.00063 19.6 0.2 0.0064 16.3 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Transglut_core3 PF13471.1 EIW76910.1 - 0.023 14.5 0.6 0.13 12.1 0.1 2.3 2 0 0 2 2 2 0 Transglutaminase-like superfamily Tyr-DNA_phospho PF06087.7 EIW76911.1 - 2.4e-51 174.7 0.0 6.3e-51 173.3 0.0 1.6 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase UIM PF02809.15 EIW76911.1 - 0.0009 18.6 6.9 0.004 16.5 1.8 2.9 2 1 0 2 2 2 1 Ubiquitin interaction motif PLDc_2 PF13091.1 EIW76911.1 - 0.0024 17.6 0.0 0.59 9.8 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain DUF2057 PF09829.4 EIW76911.1 - 0.066 12.8 0.6 0.11 12.1 0.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) WD40 PF00400.27 EIW76913.1 - 3.8e-88 286.5 27.1 6.2e-13 48.0 0.1 11.2 11 0 0 11 11 11 11 WD domain, G-beta repeat eIF2A PF08662.6 EIW76913.1 - 7e-11 42.1 0.0 0.02 14.5 0.0 5.0 1 1 3 5 5 5 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIW76913.1 - 3.8e-06 25.3 4.2 0.29 9.2 0.0 5.8 3 1 1 6 6 6 2 Nucleoporin Nup120/160 PD40 PF07676.7 EIW76913.1 - 8.4e-06 25.3 13.0 0.94 9.2 0.0 7.6 9 0 0 9 9 9 2 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EIW76913.1 - 0.00019 20.6 0.5 3.4 6.6 0.0 5.2 3 2 3 7 7 7 1 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 EIW76913.1 - 0.0005 19.5 5.4 0.88 8.9 0.1 3.5 2 1 0 3 3 3 2 PQQ-like domain Cytochrom_D1 PF02239.11 EIW76913.1 - 0.0006 18.2 0.0 0.99 7.6 0.0 3.8 4 1 0 4 4 4 2 Cytochrome D1 heme domain DPPIV_N PF00930.16 EIW76913.1 - 0.017 13.7 1.2 9 4.7 0.0 3.9 4 1 1 5 5 5 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region BBS2_Mid PF14783.1 EIW76913.1 - 0.068 12.9 0.0 25 4.6 0.0 4.3 5 0 0 5 5 5 0 Ciliary BBSome complex subunit 2, middle region TFIIIC_delta PF12657.2 EIW76913.1 - 0.57 9.8 3.0 30 4.2 0.1 4.2 3 2 0 4 4 4 0 Transcription factor IIIC subunit delta N-term Proteasome_A_N PF10584.4 EIW76913.1 - 2.5 7.4 4.6 55 3.2 0.0 4.4 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature HUN PF08729.5 EIW76914.1 - 3.9e-12 45.8 0.2 1.2e-11 44.2 0.2 2.0 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Nop14 PF04147.7 EIW76914.1 - 0.0062 14.5 15.6 0.011 13.6 10.8 1.4 1 0 0 1 1 1 1 Nop14-like family Daxx PF03344.10 EIW76914.1 - 0.0067 14.9 18.0 0.015 13.8 12.5 1.5 1 0 0 1 1 1 1 Daxx Family UBN_AB PF14075.1 EIW76914.1 - 0.0086 15.7 0.0 0.0086 15.7 0.0 2.8 2 1 0 2 2 2 1 Ubinuclein conserved middle domain DUF1510 PF07423.6 EIW76914.1 - 0.57 9.5 10.8 1.5 8.1 7.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SDA1 PF05285.7 EIW76914.1 - 2 7.6 17.1 4.4 6.5 11.9 1.5 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.9 EIW76914.1 - 8.1 4.3 10.0 12 3.7 6.9 1.2 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.27 EIW76915.1 - 2.1e-106 344.3 41.3 1.2e-12 47.1 0.1 14.6 14 1 0 14 14 14 14 WD domain, G-beta repeat eIF2A PF08662.6 EIW76915.1 - 4.2e-16 59.2 0.0 8.2e-05 22.3 0.0 5.2 3 2 3 6 6 6 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EIW76915.1 - 1.4e-06 27.9 14.1 0.01 15.3 1.2 5.4 2 1 2 4 4 4 2 PQQ-like domain PD40 PF07676.7 EIW76915.1 - 8.9e-06 25.2 8.1 9.3 6.0 0.0 8.1 8 0 0 8 8 8 2 WD40-like Beta Propeller Repeat DUF1513 PF07433.6 EIW76915.1 - 2.9e-05 23.1 1.2 0.0067 15.3 0.0 4.2 5 1 0 5 5 5 1 Protein of unknown function (DUF1513) BBS2_Mid PF14783.1 EIW76915.1 - 8.7e-05 22.2 0.0 15 5.3 0.0 6.1 6 1 0 6 6 6 0 Ciliary BBSome complex subunit 2, middle region Peptidase_S9_N PF02897.10 EIW76915.1 - 0.00013 20.7 0.1 0.035 12.6 0.0 4.2 5 1 1 6 6 6 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Nup160 PF11715.3 EIW76915.1 - 0.0021 16.2 2.3 1 7.4 0.0 5.4 5 2 2 7 7 7 1 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EIW76915.1 - 0.045 14.0 19.9 3.8 7.9 0.2 7.7 6 2 3 9 9 9 0 PQQ-like domain Antig_Caf1 PF09255.5 EIW76915.1 - 0.054 13.3 0.2 51 3.7 0.0 3.4 3 0 0 3 3 3 0 Caf1 Capsule antigen Nucleoporin_N PF08801.6 EIW76915.1 - 0.13 10.9 0.0 4.4 5.9 0.0 3.3 3 1 0 3 3 3 0 Nup133 N terminal like Proteasome_A_N PF10584.4 EIW76915.1 - 2.3 7.6 10.6 19 4.6 0.0 6.1 8 0 0 8 8 8 0 Proteasome subunit A N-terminal signature AA_permease_2 PF13520.1 EIW76916.1 - 7.4e-45 153.2 60.5 9.1e-45 152.9 41.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIW76916.1 - 1.5e-25 89.4 54.5 1.9e-25 89.1 37.8 1.0 1 0 0 1 1 1 1 Amino acid permease Peptidase_M56 PF05569.6 EIW76916.1 - 0.009 15.0 0.3 0.009 15.0 0.2 2.4 3 0 0 3 3 3 1 BlaR1 peptidase M56 DAD PF02109.11 EIW76916.1 - 0.21 11.6 3.9 2 8.5 0.7 2.5 2 0 0 2 2 2 0 DAD family Fijivirus_P9-2 PF06837.6 EIW76917.1 - 0.97 8.5 4.9 1.8 7.6 3.4 1.4 1 0 0 1 1 1 0 Fijivirus P9-2 protein NAD_binding_4 PF07993.7 EIW76918.1 - 1.4e-34 119.2 0.0 2e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EIW76918.1 - 1e-27 96.5 0.0 2.1e-27 95.5 0.0 1.5 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EIW76918.1 - 3.9e-08 33.0 0.0 6.7e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EIW76918.1 - 0.0041 17.3 0.0 0.0096 16.1 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hairy_orange PF07527.8 EIW76918.1 - 0.89 9.3 3.1 4.9 6.9 0.6 3.0 3 0 0 3 3 3 0 Hairy Orange DUF4131 PF13567.1 EIW76919.1 - 4.6 6.6 6.6 3.9 6.8 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Sugar_tr PF00083.19 EIW76920.1 - 3.1e-90 302.9 22.3 3.5e-90 302.7 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW76920.1 - 5.7e-29 100.9 42.1 5.2e-27 94.4 13.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3432 PF11914.3 EIW76925.1 - 1.1 9.3 12.0 1.4 8.9 7.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3432) Glyco_hydro_38 PF01074.17 EIW76926.1 - 4.2e-82 275.4 0.2 6.5e-82 274.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EIW76926.1 - 6.2e-58 196.6 0.0 8.8e-58 196.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EIW76926.1 - 8.4e-26 90.0 0.0 1.7e-25 89.0 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Aldedh PF00171.17 EIW76927.1 - 6.1e-76 255.6 0.0 7.5e-76 255.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family WD40 PF00400.27 EIW76928.1 - 6.2e-196 628.2 108.6 8.2e-12 44.5 0.0 28.6 28 0 0 28 28 28 26 WD domain, G-beta repeat eIF2A PF08662.6 EIW76928.1 - 4.8e-30 104.7 0.0 0.00026 20.7 0.0 11.7 8 4 3 12 12 12 6 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIW76928.1 - 4.6e-18 64.6 20.6 0.0038 15.4 0.0 14.8 7 5 6 14 14 14 5 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EIW76928.1 - 4e-15 55.9 29.0 2.7e-08 33.5 0.2 9.7 3 2 5 8 8 8 3 PQQ-like domain PD40 PF07676.7 EIW76928.1 - 7.1e-13 47.9 30.2 1.5 8.6 0.0 16.9 21 0 0 21 21 21 3 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EIW76928.1 - 1.9e-12 46.8 5.2 0.25 10.3 0.0 10.7 8 3 3 11 11 11 4 Neuroblastoma-amplified sequence, N terminal Hira PF07569.6 EIW76928.1 - 3e-08 33.1 0.0 1.2 8.2 0.0 7.7 8 2 1 9 9 9 2 TUP1-like enhancer of split Cytochrom_D1 PF02239.11 EIW76928.1 - 1.1e-07 30.4 13.4 0.31 9.2 0.1 8.2 4 3 4 9 9 9 3 Cytochrome D1 heme domain IKI3 PF04762.7 EIW76928.1 - 1.3e-07 29.8 0.1 0.15 9.8 0.0 5.8 5 1 1 6 6 6 3 IKI3 family Nucleoporin_N PF08801.6 EIW76928.1 - 2.5e-05 23.2 11.4 1.9 7.1 0.1 9.3 5 4 3 8 8 8 1 Nup133 N terminal like Proteasome_A_N PF10584.4 EIW76928.1 - 0.00011 21.3 12.8 9.1 5.7 0.1 10.1 12 0 0 12 12 12 1 Proteasome subunit A N-terminal signature Coatomer_WDAD PF04053.9 EIW76928.1 - 0.0025 16.6 0.0 14 4.3 0.0 4.5 5 1 0 5 5 5 0 Coatomer WD associated region DUF3312 PF11768.3 EIW76928.1 - 0.0043 15.3 0.0 47 2.0 0.0 5.4 7 0 0 7 7 7 0 Protein of unknown function (DUF3312) PQQ_3 PF13570.1 EIW76928.1 - 0.13 12.5 45.1 0.4 11.0 0.1 13.2 13 5 6 19 19 18 0 PQQ-like domain adh_short PF00106.20 EIW76929.1 - 1.3e-11 44.7 0.9 2.3e-11 43.9 0.6 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW76929.1 - 1.8e-05 24.6 0.1 2.5e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1598 PF07643.6 EIW76929.1 - 0.005 16.8 0.1 0.38 10.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1598) YjeF_N PF03853.10 EIW76929.1 - 0.0078 15.8 0.2 0.094 12.3 0.0 2.1 2 0 0 2 2 2 1 YjeF-related protein N-terminus 3HCDH_N PF02737.13 EIW76929.1 - 0.012 15.2 0.2 0.029 14.0 0.1 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain adh_short PF00106.20 EIW76930.1 - 5.2e-16 59.0 0.5 9.8e-16 58.1 0.3 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW76930.1 - 6.2e-06 26.1 0.4 7.9e-06 25.8 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase YjeF_N PF03853.10 EIW76930.1 - 0.0014 18.3 0.5 0.078 12.5 0.0 2.2 2 0 0 2 2 2 1 YjeF-related protein N-terminus DUF1776 PF08643.5 EIW76930.1 - 0.0022 17.1 0.0 0.0034 16.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3HCDH_N PF02737.13 EIW76930.1 - 0.0057 16.3 0.5 0.028 14.0 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GMC_oxred_N PF00732.14 EIW76931.1 - 4.5e-63 213.1 0.0 6.1e-63 212.7 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIW76931.1 - 1.2e-33 116.3 0.0 2.5e-33 115.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EIW76931.1 - 0.00032 19.7 0.1 0.00052 19.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EIW76931.1 - 0.00086 18.2 0.1 0.061 12.1 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EIW76931.1 - 0.0034 16.3 0.1 1.1 8.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW76931.1 - 0.014 15.4 0.1 0.045 13.7 0.1 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIW76931.1 - 0.042 12.9 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 EIW76931.1 - 0.075 12.8 0.1 0.77 9.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIW76931.1 - 0.99 8.4 3.2 3.8 6.4 0.1 2.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase WD40 PF00400.27 EIW76933.1 - 1.3e-105 341.9 57.0 2.2e-11 43.1 0.0 14.5 14 0 0 14 14 14 14 WD domain, G-beta repeat eIF2A PF08662.6 EIW76933.1 - 3.6e-16 59.4 0.0 0.00012 21.8 0.0 6.7 3 2 3 7 7 7 4 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EIW76933.1 - 2.3e-10 39.8 14.9 0.36 10.5 0.0 10.1 12 0 0 12 12 12 4 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.2 EIW76933.1 - 7.5e-06 25.7 4.6 0.02 14.6 0.0 5.3 6 1 0 7 7 7 2 Transcription factor IIIC subunit delta N-term Proteasome_A_N PF10584.4 EIW76933.1 - 0.0046 16.2 2.4 78 2.7 0.0 6.5 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature Nup160 PF11715.3 EIW76933.1 - 0.0076 14.4 0.8 2.4 6.1 0.0 4.2 5 0 0 5 5 5 1 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EIW76933.1 - 0.052 13.8 17.0 7.2 7.0 0.0 7.0 7 2 1 8 8 8 0 PQQ-like domain WD40 PF00400.27 EIW76934.1 - 1.7e-83 271.7 42.8 5.2e-09 35.6 0.5 12.5 12 0 0 12 12 12 12 WD domain, G-beta repeat eIF2A PF08662.6 EIW76934.1 - 4.7e-11 42.7 0.0 0.00076 19.2 0.0 5.7 2 2 4 6 6 6 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EIW76934.1 - 0.00022 20.7 13.5 0.25 11.0 0.1 7.0 9 0 0 9 9 9 2 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 EIW76934.1 - 0.00042 19.8 6.9 0.13 11.6 0.1 4.2 3 2 0 3 3 3 2 PQQ-like domain Coatomer_WDAD PF04053.9 EIW76934.1 - 0.0026 16.6 0.0 1.4 7.6 0.0 2.7 3 0 0 3 3 3 2 Coatomer WD associated region DUF3312 PF11768.3 EIW76934.1 - 0.0037 15.5 0.0 3.5 5.7 0.0 3.6 4 1 1 5 5 5 2 Protein of unknown function (DUF3312) Proteasome_A_N PF10584.4 EIW76934.1 - 0.06 12.6 9.9 12 5.3 0.0 6.2 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature TFIIIC_delta PF12657.2 EIW76934.1 - 0.084 12.5 9.8 20 4.8 0.0 5.9 6 2 1 7 7 7 0 Transcription factor IIIC subunit delta N-term Sugar_tr PF00083.19 EIW76935.1 - 2.8e-86 289.9 24.9 3.2e-86 289.7 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW76935.1 - 4.4e-21 74.9 54.6 2.3e-19 69.3 17.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Aldedh PF00171.17 EIW76937.1 - 1.5e-75 254.3 0.0 1.8e-75 254.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PRCC PF10253.4 EIW76937.1 - 0.19 12.4 0.1 0.32 11.6 0.1 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting WD40 PF00400.27 EIW76938.1 - 3.2e-94 305.7 46.1 3.2e-12 45.8 0.0 14.1 15 0 0 15 15 15 12 WD domain, G-beta repeat Nup160 PF11715.3 EIW76938.1 - 3.1e-09 35.5 5.7 0.1 10.7 0.0 7.1 3 1 1 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EIW76938.1 - 5.3e-08 31.5 0.6 0.034 12.4 0.0 4.1 2 1 3 5 5 5 3 Cytochrome D1 heme domain eIF2A PF08662.6 EIW76938.1 - 1.1e-07 31.7 0.0 0.2 11.3 0.0 5.7 4 1 1 5 5 5 2 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EIW76938.1 - 3.4e-07 29.6 3.6 0.069 12.2 0.0 5.7 3 1 2 7 7 7 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 EIW76938.1 - 6.6e-07 28.8 1.0 6.6 6.5 0.0 7.7 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 EIW76938.1 - 0.00013 21.2 0.1 4.3 6.7 0.0 5.2 5 0 0 5 5 5 1 Proteasome subunit A N-terminal signature Hira PF07569.6 EIW76938.1 - 0.026 13.7 0.0 1.6 7.8 0.0 3.3 3 0 0 3 3 3 0 TUP1-like enhancer of split DUF2415 PF10313.4 EIW76938.1 - 0.078 12.6 0.1 8.6 6.1 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) adh_short PF00106.20 EIW76939.1 - 2e-13 50.6 1.8 3.2e-13 49.9 1.2 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW76939.1 - 2.2e-08 34.1 0.1 4.2e-08 33.2 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 EIW76939.1 - 0.0041 16.8 0.3 0.0089 15.6 0.1 1.6 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PS_Dcarbxylase PF02666.10 EIW76942.1 - 7.7e-35 120.0 0.0 1.1e-34 119.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.3 EIW76942.1 - 2.5e-28 98.4 0.0 3.7e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase Asp PF00026.18 EIW76944.1 - 3.8e-66 223.5 7.6 4.4e-66 223.2 5.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW76944.1 - 9e-09 35.4 2.2 3.2e-08 33.6 1.5 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIW76944.1 - 0.0031 17.9 0.6 0.11 12.9 0.1 3.3 3 2 1 4 4 4 1 Aspartyl protease TAXi_C PF14541.1 EIW76944.1 - 0.013 15.0 0.1 5.7 6.4 0.0 2.6 2 0 0 2 2 2 0 Xylanase inhibitor C-terminal Pyr_redox_3 PF13738.1 EIW76945.1 - 5.3e-20 72.3 0.0 2.1e-18 67.1 0.0 2.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW76945.1 - 1.6e-10 40.4 0.0 6.8e-09 35.0 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EIW76945.1 - 3.3e-08 33.4 0.0 4.4e-05 23.2 0.0 3.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EIW76945.1 - 8.5e-08 32.3 0.0 2.3e-06 27.6 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIW76945.1 - 7e-07 27.8 0.0 5e-06 25.0 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EIW76945.1 - 6.9e-06 26.0 0.1 4.3e-05 23.4 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIW76945.1 - 0.00027 20.0 0.1 0.025 13.6 0.0 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EIW76945.1 - 0.00053 19.0 0.6 0.0036 16.2 0.1 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EIW76945.1 - 0.0013 17.8 0.0 0.0039 16.2 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.19 EIW76945.1 - 0.0017 17.2 0.0 0.0034 16.2 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 EIW76945.1 - 0.0023 18.1 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding HI0933_like PF03486.9 EIW76945.1 - 0.0051 15.3 0.7 0.22 9.9 0.0 3.1 3 1 1 4 4 4 1 HI0933-like protein Pyr_redox PF00070.22 EIW76945.1 - 0.007 16.7 0.1 3.9 7.9 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EIW76945.1 - 0.011 15.8 0.0 1.8 8.6 0.0 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase PA PF02225.17 EIW76945.1 - 0.014 15.0 0.0 0.04 13.6 0.0 1.8 1 0 0 1 1 1 0 PA domain ThiF PF00899.16 EIW76945.1 - 0.11 12.3 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 ThiF family Oxidored_FMN PF00724.15 EIW76946.1 - 3.7e-94 315.5 0.0 4.2e-94 315.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Asp PF00026.18 EIW76947.1 - 7e-71 239.0 3.0 8.4e-71 238.8 2.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW76947.1 - 2.9e-08 33.8 2.5 1.3e-07 31.6 1.7 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIW76947.1 - 1.1e-05 25.0 0.0 0.00052 19.5 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EIW76947.1 - 0.00045 20.6 0.0 0.092 13.2 0.0 2.9 2 1 0 2 2 2 1 Aspartyl protease GATA PF00320.22 EIW76948.1 - 4.2e-26 90.0 17.8 1.3e-15 56.4 1.8 2.5 2 0 0 2 2 2 2 GATA zinc finger DUF1752 PF08550.5 EIW76948.1 - 3.5e-11 42.4 0.6 7e-11 41.4 0.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) TF_Zn_Ribbon PF08271.7 EIW76948.1 - 0.12 11.7 6.6 0.14 11.4 0.5 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding Elf1 PF05129.8 EIW76948.1 - 1.2 8.9 3.8 4.1 7.1 0.0 2.6 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like DZR PF12773.2 EIW76948.1 - 1.7 8.5 8.4 1.2 8.9 0.4 2.8 2 1 1 3 3 3 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 EIW76948.1 - 2.2 8.2 6.8 8.1 6.4 0.3 3.1 3 0 0 3 3 3 0 Zinc ribbon domain Cytochrome_C7 PF14522.1 EIW76948.1 - 3.8 7.2 8.9 0.46 10.1 0.3 2.9 3 0 0 3 3 3 0 Cytochrome c7 zf-RING_3 PF14369.1 EIW76948.1 - 3.8 7.5 7.0 0.22 11.5 0.5 2.2 2 0 0 2 2 2 0 zinc-finger eIF-5_eIF-2B PF01873.12 EIW76948.1 - 5.4 6.6 8.3 7.8 6.1 0.6 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Ribosomal_L14 PF00238.14 EIW76949.1 - 1.5e-32 111.8 0.0 1.7e-32 111.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e NACHT PF05729.7 EIW76950.1 - 5.7e-09 35.8 0.0 7.4e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW76950.1 - 2e-07 31.1 0.0 2.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.10 EIW76950.1 - 1.7e-05 23.6 0.0 2.2e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EIW76950.1 - 0.00024 21.2 0.0 0.00036 20.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EIW76950.1 - 0.00024 21.2 0.0 0.00066 19.8 0.0 1.7 2 0 0 2 2 1 1 RNA helicase AAA_19 PF13245.1 EIW76950.1 - 0.00042 19.9 0.0 0.0007 19.2 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 EIW76950.1 - 0.00092 18.6 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EIW76950.1 - 0.0011 19.7 0.0 0.0019 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIW76950.1 - 0.0013 19.0 0.0 0.0018 18.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EIW76950.1 - 0.0015 18.2 0.0 0.0021 17.8 0.0 1.3 1 1 0 1 1 1 1 NTPase ABC_tran PF00005.22 EIW76950.1 - 0.0025 18.0 0.0 0.0034 17.6 0.0 1.3 1 1 0 1 1 1 1 ABC transporter ArgK PF03308.11 EIW76950.1 - 0.0032 16.2 0.0 0.0044 15.8 0.0 1.1 1 0 0 1 1 1 1 ArgK protein AAA_10 PF12846.2 EIW76950.1 - 0.0073 15.7 0.0 0.0095 15.4 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain APS_kinase PF01583.15 EIW76950.1 - 0.008 15.8 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase FtsK_SpoIIIE PF01580.13 EIW76950.1 - 0.009 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_14 PF13173.1 EIW76950.1 - 0.01 15.7 0.0 0.014 15.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EIW76950.1 - 0.011 16.2 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein AAA_5 PF07728.9 EIW76950.1 - 0.012 15.2 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 EIW76950.1 - 0.016 14.2 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 EIW76950.1 - 0.017 14.0 0.0 0.021 13.7 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein KTI12 PF08433.5 EIW76950.1 - 0.019 14.1 0.0 0.021 14.0 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 EIW76950.1 - 0.02 14.8 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIW76950.1 - 0.021 14.0 0.0 0.031 13.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 MobB PF03205.9 EIW76950.1 - 0.022 14.4 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EIW76950.1 - 0.023 13.8 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.1 EIW76950.1 - 0.028 13.9 0.0 0.043 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EIW76950.1 - 0.033 13.8 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 EIW76950.1 - 0.035 12.9 0.0 0.043 12.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.24 EIW76950.1 - 0.042 14.0 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EIW76950.1 - 0.056 13.4 0.0 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain cobW PF02492.14 EIW76950.1 - 0.064 12.6 0.0 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.13 EIW76950.1 - 0.069 12.6 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 EIW76950.1 - 0.077 11.9 0.0 0.09 11.7 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain AAA_25 PF13481.1 EIW76950.1 - 0.088 12.2 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Neil1-DNA_bind PF09292.5 EIW76950.1 - 0.12 12.1 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Endonuclease VIII-like 1, DNA bind AAA_23 PF13476.1 EIW76950.1 - 0.13 12.5 0.0 0.19 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EIW76950.1 - 0.15 11.7 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 Archaeal ATPase RNA12 PF10443.4 EIW76950.1 - 0.15 10.5 0.0 0.16 10.4 0.0 1.1 1 0 0 1 1 1 0 RNA12 protein Asp PF00026.18 EIW76951.1 - 5.7e-59 199.9 1.7 7e-59 199.6 1.2 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW76951.1 - 3.9e-06 26.9 0.3 1.4e-05 25.0 0.2 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIW76951.1 - 0.00015 22.1 0.0 0.02 15.3 0.0 2.8 2 1 1 3 3 3 1 Aspartyl protease TAXi_C PF14541.1 EIW76951.1 - 0.0023 17.4 0.0 0.052 13.0 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Sugar_tr PF00083.19 EIW76952.1 - 2.3e-86 290.1 24.6 2.6e-86 289.9 17.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW76952.1 - 9.9e-23 80.4 43.1 5.3e-17 61.5 18.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIW76952.1 - 0.00019 19.7 4.7 0.00019 19.7 3.3 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF1228 PF06779.9 EIW76952.1 - 0.0018 18.2 9.7 0.043 13.8 0.8 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1228) NapB PF03892.9 EIW76953.1 - 0.12 12.0 2.0 1.3 8.7 0.7 2.2 2 0 0 2 2 2 0 Nitrate reductase cytochrome c-type subunit (NapB) ATG13 PF10033.4 EIW76956.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 13 SNARE_assoc PF09335.6 EIW76957.1 - 1.9e-10 41.0 7.0 1.9e-10 41.0 4.8 1.9 2 1 0 2 2 2 1 SNARE associated Golgi protein DUF4129 PF13559.1 EIW76957.1 - 0.0091 15.9 0.6 0.02 14.8 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) ABC_tran PF00005.22 EIW76959.1 - 6.3e-45 152.8 0.0 5.1e-29 101.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIW76959.1 - 2.2e-34 119.1 26.3 4e-18 65.8 3.5 3.3 3 2 0 3 3 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EIW76959.1 - 1.8e-09 37.1 0.0 0.0014 17.8 0.6 3.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EIW76959.1 - 2.3e-05 23.9 0.0 0.26 10.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIW76959.1 - 0.00011 22.3 0.4 1.1 9.4 0.1 3.9 3 1 0 3 3 3 1 AAA domain AAA_21 PF13304.1 EIW76959.1 - 0.00016 21.7 0.8 1.3 8.9 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EIW76959.1 - 0.00078 18.9 0.3 0.14 11.7 0.0 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EIW76959.1 - 0.002 17.6 0.0 0.57 9.5 0.0 2.9 3 0 0 3 3 3 1 AAA-like domain T2SE PF00437.15 EIW76959.1 - 0.0045 15.9 0.0 1.2 7.9 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF4534 PF15049.1 EIW76959.1 - 0.0058 16.2 0.8 0.24 11.0 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4534) AAA_16 PF13191.1 EIW76959.1 - 0.015 15.3 1.5 1.6 8.7 0.0 3.2 2 1 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EIW76959.1 - 0.021 14.2 0.0 2.8 7.3 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family KaiC PF06745.8 EIW76959.1 - 0.039 13.0 0.2 3.8 6.5 0.0 2.3 2 0 0 2 2 2 0 KaiC DUF87 PF01935.12 EIW76959.1 - 0.04 13.7 0.2 0.084 12.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 Miro PF08477.8 EIW76959.1 - 0.17 12.4 3.8 25 5.4 0.1 3.7 4 0 0 4 4 4 0 Miro-like protein DUF2075 PF09848.4 EIW76959.1 - 0.55 9.1 0.4 6.7 5.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.14 EIW76959.1 - 0.89 8.9 3.2 1.6 8.1 0.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.1 EIW76959.1 - 1.1 9.5 3.2 7.8 6.7 0.0 2.6 3 0 0 3 3 3 0 AAA domain Zn_clus PF00172.13 EIW76960.1 - 2.5e-06 27.3 7.4 4.6e-06 26.4 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin_N PF00134.18 EIW76961.1 - 6.6e-05 22.4 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EIW76961.1 - 0.0025 18.2 0.0 0.0041 17.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin DDE_3 PF13358.1 EIW76964.1 - 3.5e-08 33.3 0.0 7.3e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease Glycolytic PF00274.14 EIW76966.1 - 0.13 10.6 0.0 0.2 10.0 0.0 1.2 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-I Zn_clus PF00172.13 EIW76968.1 - 2.1e-05 24.3 6.5 4.3e-05 23.3 4.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SNARE_assoc PF09335.6 EIW76970.1 - 7.1e-16 58.5 6.5 7.1e-16 58.5 4.5 1.7 1 1 1 2 2 2 1 SNARE associated Golgi protein FUSC_2 PF13515.1 EIW76970.1 - 3 7.7 10.5 0.76 9.6 4.6 2.0 1 1 0 1 1 1 0 Fusaric acid resistance protein-like WD40 PF00400.27 EIW76971.1 - 0.01 15.7 13.3 0.52 10.2 1.1 6.1 7 0 0 7 7 7 0 WD domain, G-beta repeat RRM_6 PF14259.1 EIW76972.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RNB PF00773.14 EIW76973.1 - 3.6e-91 305.8 0.1 5.3e-91 305.2 0.1 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EIW76973.1 - 1e-10 41.7 2.0 1.2e-10 41.6 0.1 2.2 2 1 0 2 2 2 1 PIN domain OB_RNB PF08206.6 EIW76973.1 - 0.011 15.2 1.6 0.19 11.2 0.0 2.8 2 0 0 2 2 2 0 Ribonuclease B OB domain Peptidase_M20 PF01546.23 EIW76973.1 - 0.033 13.6 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 Peptidase family M20/M25/M40 Oxidored_FMN PF00724.15 EIW76974.1 - 1.6e-87 293.6 0.0 1.8e-87 293.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family WD40 PF00400.27 EIW76975.1 - 2e-54 179.6 19.6 4e-14 51.8 1.2 8.1 7 1 1 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 EIW76975.1 - 8.6e-06 25.5 0.0 0.0012 18.5 0.0 3.2 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EIW76975.1 - 0.0025 17.4 0.7 2 8.1 0.0 3.8 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EIW76975.1 - 0.02 14.0 0.2 4.8 6.1 0.1 2.9 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal DUF3312 PF11768.3 EIW76975.1 - 0.034 12.3 0.0 0.54 8.4 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3312) DUF2845 PF11006.3 EIW76975.1 - 0.046 13.5 0.1 0.4 10.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2845) Velvet PF11754.3 EIW76977.1 - 9.6e-56 188.6 0.0 2.4e-55 187.2 0.0 1.7 1 1 0 1 1 1 1 Velvet factor SNARE_assoc PF09335.6 EIW76978.1 - 1.3e-16 60.8 7.6 1.7e-16 60.5 4.5 1.8 2 0 0 2 2 2 1 SNARE associated Golgi protein PDR_CDR PF06422.7 EIW76978.1 - 0.0029 17.2 0.2 2.3 7.9 0.0 2.5 2 0 0 2 2 2 2 CDR ABC transporter EphA2_TM PF14575.1 EIW76978.1 - 1.6 9.1 4.1 1.7 9.1 0.1 2.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain His_Phos_2 PF00328.17 EIW76979.1 - 2.1e-13 50.3 0.0 4.7e-13 49.1 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Exo_endo_phos PF03372.18 EIW76980.1 - 5.3e-09 36.3 0.1 1.8e-08 34.6 0.1 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Glyco_hydro_3 PF00933.16 EIW76982.1 - 9.4e-69 231.6 0.1 1.4e-68 231.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain DUF883 PF05957.8 EIW76983.1 - 0.64 10.4 4.1 0.15 12.4 0.2 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Sugar_tr PF00083.19 EIW76984.1 - 4.1e-22 78.3 15.8 5e-22 78.0 10.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW76984.1 - 4.4e-05 22.3 15.7 6.9e-05 21.7 10.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily FTCD_C PF04961.7 EIW76986.1 - 0.063 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase DUF2762 PF10960.3 EIW76989.1 - 0.091 12.4 0.8 0.25 11.0 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) DER1 PF04511.10 EIW76993.1 - 8.5e-29 100.4 0.5 1.1e-28 100.1 0.3 1.0 1 0 0 1 1 1 1 Der1-like family LtrA PF06772.6 EIW76993.1 - 0.098 11.5 2.3 0.11 11.4 0.8 1.5 1 1 1 2 2 2 0 Bacterial low temperature requirement A protein (LtrA) Ycf4 PF02392.11 EIW76993.1 - 0.17 11.2 0.2 0.26 10.6 0.2 1.4 1 0 0 1 1 1 0 Ycf4 MFS_1 PF07690.11 EIW76994.1 - 1.4e-19 70.0 52.3 1.1e-12 47.3 14.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-RING_2 PF13639.1 EIW76996.1 - 1.1e-06 28.4 9.7 1.9e-06 27.5 6.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIW76996.1 - 2.9e-05 24.0 6.3 7.7e-05 22.7 4.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 EIW76996.1 - 0.00018 21.3 5.8 0.00032 20.5 4.0 1.4 1 0 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 EIW76996.1 - 0.0091 15.8 3.4 0.019 14.8 2.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_RING PF05883.6 EIW76996.1 - 0.35 10.7 1.1 0.67 9.7 0.8 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-C3HC4 PF00097.20 EIW76996.1 - 0.69 9.6 10.9 1.2 8.8 7.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EIW76996.1 - 0.78 9.8 8.7 1.5 8.9 6.0 1.5 1 0 0 1 1 1 0 RING-variant domain C1_1 PF00130.17 EIW76996.1 - 3.6 7.3 7.3 6.9 6.4 5.1 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.1 EIW76996.1 - 9.3 6.3 11.7 17 5.5 8.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 EIW76997.1 - 8.6e-40 135.9 0.0 5e-38 130.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW76997.1 - 4.4e-19 68.1 0.1 1.2e-18 66.6 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EIW76997.1 - 0.016 13.9 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain ResIII PF04851.10 EIW76997.1 - 0.073 12.8 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Rrn6 PF10214.4 EIW77000.1 - 0.16 10.0 5.3 0.21 9.6 3.7 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF605 PF04652.11 EIW77000.1 - 0.24 10.7 25.4 0.42 9.9 17.6 1.4 1 0 0 1 1 1 0 Vta1 like Suf PF05843.9 EIW77000.1 - 1.2 8.8 8.1 2 8.0 5.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.11 EIW77000.1 - 3.4 7.4 4.4 6.1 6.6 3.1 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region T4_deiodinase PF00837.12 EIW77001.1 - 0.11 11.4 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Iodothyronine deiodinase CTP_synth_N PF06418.9 EIW77003.1 - 6.5e-117 389.5 0.0 8.7e-117 389.1 0.0 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EIW77003.1 - 6.7e-50 169.2 0.0 1.1e-49 168.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CbiA PF01656.18 EIW77003.1 - 0.0024 17.3 0.0 0.005 16.2 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Peptidase_C26 PF07722.8 EIW77003.1 - 0.016 14.6 0.1 0.058 12.8 0.0 1.9 1 1 0 1 1 1 0 Peptidase C26 GATase_3 PF07685.9 EIW77003.1 - 0.059 12.9 0.1 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain 2-Hacid_dh_C PF02826.14 EIW77004.1 - 8e-36 122.8 0.0 1.1e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIW77004.1 - 2.2e-25 88.6 0.0 2.8e-25 88.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain F420_oxidored PF03807.12 EIW77004.1 - 0.0053 17.1 0.0 0.0095 16.3 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent WD40 PF00400.27 EIW77005.1 - 8.3e-35 117.4 10.8 2.3e-08 33.6 0.2 5.8 6 0 0 6 6 6 5 WD domain, G-beta repeat Glyco_hydro_1 PF00232.13 EIW77006.1 - 4.3e-156 519.6 0.3 4.8e-156 519.4 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.13 EIW77007.1 - 3e-41 141.4 1.0 4.2e-41 141.0 0.7 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ATP-synt_DE PF00401.15 EIW77009.1 - 1.6 8.6 4.9 6.5 6.7 0.9 2.4 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain Myticin-prepro PF10690.4 EIW77010.1 - 0.28 11.2 1.1 0.52 10.3 0.0 1.9 2 0 0 2 2 2 0 Myticin pre-proprotein from the mussel WD40 PF00400.27 EIW77012.1 - 1.1e-66 218.5 26.4 1e-13 50.5 1.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EIW77012.1 - 1.6e-05 23.8 0.1 0.071 11.8 0.1 4.5 1 1 1 3 3 3 1 Nup133 N terminal like Apc4_WD40 PF12894.2 EIW77012.1 - 0.00024 20.5 0.0 2.1 7.9 0.0 4.6 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.6 EIW77012.1 - 0.0055 16.4 0.9 0.39 10.3 0.0 3.4 4 1 1 5 5 5 1 Eukaryotic translation initiation factor eIF2A TFIIIC_delta PF12657.2 EIW77012.1 - 0.45 10.2 6.5 3.6 7.2 0.4 3.6 3 2 2 5 5 5 0 Transcription factor IIIC subunit delta N-term Aminotran_1_2 PF00155.16 EIW77013.1 - 1.8e-54 185.0 0.0 2.2e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EIW77013.1 - 0.18 10.0 0.0 0.59 8.3 0.0 1.9 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme zf-MYND PF01753.13 EIW77014.1 - 1.1e-08 34.7 14.7 1.1e-08 34.7 10.2 2.2 2 0 0 2 2 2 1 MYND finger SHMT PF00464.14 EIW77015.1 - 5.2e-170 565.1 0.0 6.1e-170 564.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EIW77015.1 - 0.0034 16.5 0.0 0.041 13.0 0.0 2.0 2 0 0 2 2 2 1 Beta-eliminating lyase Glyco_hydro_35 PF01301.14 EIW77017.1 - 1.8e-65 221.3 0.9 2.7e-65 220.8 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EIW77017.1 - 4.3e-40 137.0 6.5 1.1e-39 135.7 4.5 1.7 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EIW77017.1 - 1.7e-39 134.5 18.4 2e-20 73.1 0.3 3.6 4 0 0 4 4 4 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EIW77017.1 - 2e-20 71.9 0.0 8.3e-20 69.9 0.0 2.1 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 GFA PF04828.9 EIW77018.1 - 4.9e-18 64.8 2.8 5.8e-17 61.4 1.9 2.1 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 EIW77018.1 - 0.4 10.3 0.0 0.4 10.3 0.0 2.7 3 0 0 3 3 3 0 Nudix N-terminal UCH PF00443.24 EIW77019.1 - 3.3e-40 137.8 0.0 1.1e-39 136.1 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW77019.1 - 3.6e-08 33.2 0.0 0.0014 18.1 0.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Glyco_hydro_18 PF00704.23 EIW77020.1 - 5.2e-09 36.0 2.2 6.6e-09 35.6 1.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.23 EIW77021.1 - 4.2e-13 49.4 4.5 5.5e-13 49.0 3.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MFS_1 PF07690.11 EIW77022.1 - 2e-34 118.8 38.8 2e-34 118.8 26.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW77022.1 - 1.4e-17 63.3 9.5 1.4e-17 63.3 6.6 3.0 2 1 1 3 3 3 1 Sugar (and other) transporter Ndc1_Nup PF09531.5 EIW77022.1 - 0.057 11.8 1.7 0.13 10.6 1.2 1.5 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Rnk_N PF14760.1 EIW77023.1 - 0.071 13.2 0.3 0.19 11.8 0.2 1.7 1 0 0 1 1 1 0 Rnk N-terminus RRP14 PF15459.1 EIW77023.1 - 4.8 7.3 10.2 19 5.4 0.2 3.5 3 0 0 3 3 3 0 60S ribosome biogenesis protein Rrp14 DUF2512 PF10710.4 EIW77025.1 - 0.17 11.3 4.0 0.1 12.0 1.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2512) DUF3357 PF11837.3 EIW77025.1 - 5.7 6.8 6.9 46 3.9 2.6 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3357) Glyco_hydro_18 PF00704.23 EIW77028.1 - 6.2e-59 200.1 7.9 8.7e-59 199.6 5.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.23 EIW77029.1 - 5.7e-59 200.2 3.7 6.8e-59 200.0 2.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 SRP19 PF01922.12 EIW77030.1 - 3.2e-23 82.1 0.0 4.7e-23 81.5 0.0 1.2 1 0 0 1 1 1 1 SRP19 protein Herpes_capsid PF06112.6 EIW77030.1 - 2.7 8.0 6.9 21 5.1 2.0 2.3 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein JTB PF05439.7 EIW77031.1 - 0.001 18.8 1.1 0.0027 17.4 0.7 1.9 1 1 0 1 1 1 1 Jumping translocation breakpoint protein (JTB) DUF2567 PF10821.3 EIW77031.1 - 0.043 13.3 0.3 3.6 7.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2567) zf-C2H2_4 PF13894.1 EIW77034.1 - 6.5e-13 48.0 22.4 0.0037 17.5 1.2 5.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIW77034.1 - 6.6e-10 38.8 21.1 0.00019 21.4 0.4 5.0 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EIW77034.1 - 3.4e-08 33.3 22.1 0.1 12.9 0.2 5.3 5 0 0 5 5 5 3 Zinc-finger double domain zf-C2H2 PF00096.21 EIW77034.1 - 3.6e-08 33.2 17.1 0.014 15.7 1.5 4.5 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EIW77034.1 - 1.2e-07 31.3 12.8 0.15 12.0 0.1 5.0 5 0 0 5 5 5 3 C2H2-type zinc finger zf-met PF12874.2 EIW77034.1 - 2.7e-05 24.2 13.3 0.33 11.2 0.6 4.7 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EIW77034.1 - 0.00032 20.7 14.2 0.17 12.0 2.3 4.0 1 1 2 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2HC5 PF06221.8 EIW77034.1 - 0.021 14.5 4.5 9.1 6.1 0.1 4.0 2 1 1 3 3 3 0 Putative zinc finger motif, C2HC5-type C1_1 PF00130.17 EIW77034.1 - 0.029 14.0 7.2 1.4 8.7 0.5 3.6 1 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GCC2_GCC3 PF07699.8 EIW77034.1 - 0.056 13.0 5.9 18 5.0 0.1 4.0 2 1 2 4 4 4 0 GCC2 and GCC3 zf-LYAR PF08790.6 EIW77034.1 - 0.067 12.9 15.4 0.65 9.7 0.6 4.9 5 1 0 5 5 5 0 LYAR-type C2HC zinc finger Mut7-C PF01927.11 EIW77034.1 - 0.088 12.7 15.3 0.11 12.4 2.0 3.5 1 1 1 2 2 2 0 Mut7-C RNAse domain zf-FCS PF06467.9 EIW77034.1 - 0.14 11.8 7.5 8.5 6.1 0.1 4.6 5 0 0 5 5 5 0 MYM-type Zinc finger with FCS sequence motif DUF2387 PF09526.5 EIW77034.1 - 0.22 11.4 13.7 4.2 7.3 0.3 4.0 1 1 3 4 4 4 0 Probable metal-binding protein (DUF2387) DUF3133 PF11331.3 EIW77034.1 - 0.39 10.3 3.8 2.3 7.8 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3133) C1_4 PF07975.7 EIW77034.1 - 0.52 10.3 14.9 1.1 9.3 1.8 3.6 1 1 2 3 3 3 0 TFIIH C1-like domain HypA PF01155.14 EIW77034.1 - 0.6 9.8 10.8 2.4 7.8 1.2 3.0 1 1 2 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-CHY PF05495.7 EIW77034.1 - 0.61 10.2 17.8 0.19 11.9 4.0 3.1 1 1 3 4 4 4 0 CHY zinc finger ATPase-cat_bd PF12156.3 EIW77034.1 - 0.67 10.5 10.4 1.4 9.4 0.9 2.5 1 1 2 3 3 3 0 Putative metal-binding domain of cation transport ATPase zf-U1 PF06220.7 EIW77034.1 - 0.86 9.2 3.9 0.64 9.6 0.4 2.6 3 0 0 3 3 3 0 U1 zinc finger zf-CSL PF05207.8 EIW77034.1 - 1.2 8.7 11.7 1.3 8.5 1.2 3.5 1 1 2 3 3 3 0 CSL zinc finger PyrI_C PF02748.10 EIW77034.1 - 1.2 8.6 9.8 7.9 5.9 0.3 3.9 2 1 2 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF629 PF04780.7 EIW77034.1 - 1.2 7.5 16.9 0.96 7.8 1.4 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF629) Ecl1 PF12855.2 EIW77034.1 - 1.4 8.3 6.5 2.6 7.4 0.1 3.3 4 0 0 4 4 4 0 Life-span regulatory factor zf-SNAP50_C PF12251.3 EIW77034.1 - 1.4 8.2 8.9 2 7.7 0.8 2.6 1 1 2 3 3 3 0 snRNA-activating protein of 50kDa MW C terminal zf-MYND PF01753.13 EIW77034.1 - 1.9 8.4 11.7 3.5e+03 -2.1 8.1 3.5 1 1 0 1 1 1 0 MYND finger zf-AN1 PF01428.11 EIW77034.1 - 2 8.3 16.8 20 5.1 0.1 4.7 5 0 0 5 5 4 0 AN1-like Zinc finger Galanin PF01296.13 EIW77034.1 - 2.1 8.2 5.5 1.4e+02 2.3 0.0 4.0 4 0 0 4 4 4 0 Galanin Ribosomal_L44 PF00935.14 EIW77034.1 - 2.2 8.3 9.6 13 5.8 0.1 3.7 2 1 2 4 4 4 0 Ribosomal protein L44 zinc_ribbon_4 PF13717.1 EIW77034.1 - 2.8 7.7 15.3 8.4 6.1 0.1 4.6 5 0 0 5 5 5 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EIW77034.1 - 3.4 7.7 21.8 9.8 6.2 1.9 4.4 2 2 2 4 4 4 0 Zinc ribbon domain RNHCP PF12647.2 EIW77034.1 - 3.5 7.5 14.0 11 5.9 2.2 3.8 2 1 0 3 3 3 0 RNHCP domain zinc_ribbon_5 PF13719.1 EIW77034.1 - 4.4 6.9 16.1 7.7 6.1 0.1 4.6 5 0 0 5 5 5 0 zinc-ribbon domain XPA_N PF01286.13 EIW77034.1 - 5.5 6.7 12.5 6.1 6.6 0.1 4.1 4 0 0 4 4 4 0 XPA protein N-terminal zf-RING_2 PF13639.1 EIW77035.1 - 3.6e-05 23.4 13.7 3.6e-05 23.4 9.5 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIW77035.1 - 4e-05 23.5 13.2 8.2e-05 22.5 9.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW77035.1 - 7.6e-05 22.3 15.0 0.00016 21.2 10.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIW77035.1 - 0.00014 21.4 13.2 0.00032 20.2 9.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW77035.1 - 0.0004 19.9 12.9 0.0004 19.9 8.9 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EIW77035.1 - 0.088 12.6 9.0 0.19 11.5 6.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 EIW77035.1 - 0.51 9.9 9.7 1.2 8.7 6.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.2 EIW77035.1 - 1.2 9.3 12.6 2.8 8.0 8.8 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EIW77035.1 - 1.2 9.0 11.4 2.5 8.0 6.9 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING FYVE PF01363.16 EIW77035.1 - 2.7 7.9 14.6 2.2e+02 1.8 10.1 2.8 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_UBOX PF13445.1 EIW77035.1 - 6.1 6.6 10.6 0.43 10.3 2.3 2.4 2 0 0 2 2 2 0 RING-type zinc-finger FTR1 PF03239.9 EIW77037.1 - 1.8e-63 214.3 5.2 2.2e-63 214.0 3.6 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family Wzy_C PF04932.10 EIW77037.1 - 0.0077 16.0 0.4 0.0077 16.0 0.3 2.9 3 1 0 3 3 3 1 O-Antigen ligase HlyIII PF03006.15 EIW77037.1 - 2.3 7.5 8.5 1.2 8.4 2.5 2.6 2 1 0 2 2 2 0 Haemolysin-III related Yip1 PF04893.12 EIW77037.1 - 4.7 6.6 21.3 1.3 8.5 5.1 3.2 3 1 0 3 3 3 0 Yip1 domain Cu-oxidase PF00394.17 EIW77038.1 - 8.8e-38 129.7 5.4 3.9e-32 111.3 0.1 3.6 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIW77038.1 - 2.3e-36 124.3 1.6 2.3e-36 124.3 1.1 3.2 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EIW77038.1 - 6.1e-29 100.1 10.1 4.9e-28 97.2 0.5 3.7 4 1 0 4 4 4 2 Multicopper oxidase Sec15 PF04091.7 EIW77041.1 - 0.13 11.6 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like RTA1 PF04479.8 EIW77042.1 - 1.2e-41 142.6 4.4 1.8e-41 142.0 3.1 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF1129 PF06570.6 EIW77042.1 - 0.51 9.6 6.4 0.036 13.3 0.5 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1129) DUF2975 PF11188.3 EIW77042.1 - 2.2 8.0 13.2 47 3.6 6.7 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) zf-C2H2 PF00096.21 EIW77043.1 - 1.3 9.4 12.5 15 6.1 0.0 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW77043.1 - 1.4 9.3 12.6 27 5.4 1.8 4.6 4 0 0 4 4 4 0 C2H2-type zinc finger zf-Di19 PF05605.7 EIW77043.1 - 1.7 8.8 8.6 0.36 10.9 1.0 2.8 2 2 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 EIW77043.1 - 9.5 6.6 12.0 0.51 10.6 0.1 3.9 3 1 0 3 3 3 0 C2H2-type zinc-finger domain DUF3759 PF12585.3 EIW77045.1 - 1.2e-08 34.7 0.5 1.5e-08 34.3 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) BCNT PF07572.7 EIW77046.1 - 3.3e-17 62.1 0.4 8.7e-17 60.8 0.0 1.8 2 0 0 2 2 2 1 Bucentaur or craniofacial development PufQ PF05398.6 EIW77047.1 - 2.5 8.1 7.1 6.7 6.8 0.1 3.2 3 0 0 3 3 3 0 PufQ cytochrome subunit Rad9 PF04139.8 EIW77051.1 - 0.08 12.0 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Rad9 zf-C2H2_4 PF13894.1 EIW77052.1 - 6.6e-15 54.2 82.8 0.17 12.2 0.1 20.3 21 1 0 21 21 21 6 C2H2-type zinc finger zf-C2H2 PF00096.21 EIW77052.1 - 1.9e-12 46.7 78.4 0.019 15.2 0.5 19.8 21 0 0 21 21 21 6 Zinc finger, C2H2 type zf-C3HC4_2 PF13923.1 EIW77052.1 - 0.015 15.2 1.0 0.015 15.2 0.7 6.4 8 1 0 8 8 8 0 Zinc finger, C3HC4 type (RING finger) Rubredoxin PF00301.15 EIW77052.1 - 0.023 14.5 0.5 0.023 14.5 0.3 7.1 10 0 0 10 10 10 0 Rubredoxin zf-C2H2_2 PF12756.2 EIW77052.1 - 0.32 11.1 63.0 0.21 11.7 1.1 9.2 6 3 3 9 9 9 0 C2H2 type zinc-finger (2 copies) GATA PF00320.22 EIW77052.1 - 0.76 9.1 14.0 0.89 8.9 0.1 4.9 5 1 0 5 5 5 0 GATA zinc finger zf-met PF12874.2 EIW77052.1 - 4.4 7.6 49.1 6.3 7.1 0.1 13.1 15 0 0 15 15 15 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIW77052.1 - 9.9 6.4 64.6 2.2 8.5 0.1 14.7 18 1 0 18 18 18 0 Zinc-finger double-stranded RNA-binding DUF4336 PF14234.1 EIW77053.1 - 2.5e-13 49.8 0.0 3.9e-06 26.2 0.0 3.0 2 1 1 3 3 3 3 Domain of unknown function (DUF4336) AMP_N PF05195.11 EIW77053.1 - 0.069 12.5 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain WD40 PF00400.27 EIW77054.1 - 7.3e-43 142.9 21.2 5.9e-09 35.4 0.1 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat Hira PF07569.6 EIW77054.1 - 4.7e-41 140.4 0.0 9.2e-41 139.4 0.0 1.5 1 1 0 1 1 1 1 TUP1-like enhancer of split Abhydrolase_6 PF12697.2 EIW77055.1 - 2.8e-24 86.2 0.0 3.6e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW77055.1 - 1.1e-17 64.4 0.0 5.9e-17 62.0 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW77055.1 - 3.1e-07 30.2 0.0 0.00028 20.6 0.0 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EIW77055.1 - 1.7e-05 24.4 0.0 3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.15 EIW77055.1 - 0.018 15.2 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF3515 PF12028.3 EIW77055.1 - 0.07 12.3 0.1 0.19 10.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3515) PGAP1 PF07819.8 EIW77055.1 - 0.073 12.6 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein zf-C2H2_4 PF13894.1 EIW77056.1 - 3.6e-06 26.9 13.3 0.0031 17.7 2.5 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIW77056.1 - 4.8e-05 23.3 5.1 0.0017 18.4 0.6 3.0 4 0 0 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIW77056.1 - 0.00077 19.5 14.5 0.011 15.9 0.9 3.4 4 0 0 4 4 3 2 Zinc-finger of C2H2 type zf-C3HC4_2 PF13923.1 EIW77056.1 - 0.0071 16.3 7.6 0.022 14.7 2.4 2.4 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.21 EIW77056.1 - 0.012 15.9 14.7 0.51 10.7 0.4 3.3 3 0 0 3 3 3 0 Zinc finger, C2H2 type Ta0938 PF11494.3 EIW77056.1 - 0.023 14.7 2.0 0.062 13.4 0.1 2.0 1 1 1 2 2 2 0 Ta0938 HNH PF01844.18 EIW77056.1 - 0.075 12.9 4.3 5.3 6.9 0.1 3.2 2 1 0 3 3 3 0 HNH endonuclease C1_1 PF00130.17 EIW77056.1 - 0.11 12.2 7.6 1.5 8.6 2.3 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2HC_2 PF13913.1 EIW77056.1 - 0.12 12.0 4.0 0.2 11.3 0.4 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-HIT PF04438.11 EIW77056.1 - 0.17 11.5 6.8 14 5.4 0.0 3.1 3 0 0 3 3 3 0 HIT zinc finger zf-SNAP50_C PF12251.3 EIW77056.1 - 0.35 10.2 5.9 1.1 8.5 2.1 1.9 1 1 1 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal zf-RING_2 PF13639.1 EIW77056.1 - 0.37 10.6 9.6 0.89 9.4 3.2 2.2 1 1 1 2 2 2 0 Ring finger domain zf-C3HC4_3 PF13920.1 EIW77056.1 - 0.49 10.1 11.2 0.95 9.1 4.2 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 EIW77056.1 - 0.71 9.7 6.0 26 4.7 1.2 2.1 1 1 1 2 2 2 0 Double zinc ribbon zf-Di19 PF05605.7 EIW77056.1 - 1.6 8.8 8.4 1.1 9.4 3.3 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-RING_5 PF14634.1 EIW77056.1 - 3.4 7.4 12.2 11 5.8 4.9 2.4 1 1 1 2 2 2 0 zinc-RING finger domain zf-C2H2_2 PF12756.2 EIW77056.1 - 4.5 7.4 12.2 13 6.0 4.8 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 EIW77056.1 - 6.1 7.3 13.2 3.8 7.9 1.4 3.2 3 0 0 3 3 3 0 Zinc-finger double domain FYVE_2 PF02318.11 EIW77056.1 - 6.9 6.6 7.3 2.5 8.0 1.8 1.9 1 1 0 1 1 1 0 FYVE-type zinc finger zf-PARP PF00645.13 EIW77057.1 - 8.6e-25 86.7 0.1 1.7e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Ribosomal_S26e PF01283.14 EIW77058.1 - 3.7e-51 172.1 8.4 4.4e-51 171.9 5.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e DUF1918 PF08940.6 EIW77058.1 - 0.021 14.1 0.0 0.047 13.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1918) UBN2 PF14223.1 EIW77060.1 - 7e-08 32.2 0.0 4.6e-07 29.6 0.0 2.2 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EIW77060.1 - 1.1e-06 28.2 0.0 2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Terpene_synth_C PF03936.11 EIW77061.1 - 1.3e-22 80.3 0.0 1.6e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.6 EIW77061.1 - 0.023 13.3 0.1 0.035 12.7 0.1 1.5 1 1 0 1 1 1 0 Trichodiene synthase (TRI5) F-box-like PF12937.2 EIW77062.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 F-box-like Peptidase_S10 PF00450.17 EIW77065.1 - 1.9e-114 383.0 0.1 2.4e-114 382.7 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EIW77065.1 - 2.5e-06 27.5 0.0 1e-05 25.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Pkinase PF00069.20 EIW77066.1 - 9.5e-67 224.8 0.0 1.2e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW77066.1 - 1.6e-29 102.7 0.0 2.5e-29 102.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW77066.1 - 0.42 9.5 0.3 1.7 7.5 0.1 2.0 1 1 1 2 2 2 0 Kinase-like DAO PF01266.19 EIW77067.1 - 2.9e-17 62.6 0.3 3.5e-17 62.3 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase PROL5-SMR PF15621.1 EIW77067.1 - 1.3 9.4 8.4 1.3 9.4 0.7 2.7 2 1 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family DAO PF01266.19 EIW77069.1 - 5.4e-18 65.0 0.0 1.6e-17 63.4 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW77069.1 - 5.9e-06 25.3 0.0 7.9e-06 24.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIW77069.1 - 0.0058 16.5 0.0 0.0096 15.8 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW77069.1 - 0.028 14.4 0.9 0.091 12.7 0.2 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIW77069.1 - 0.13 11.3 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 EIW77069.1 - 0.15 12.4 0.5 0.28 11.6 0.4 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MNSV_P7B PF06692.6 EIW77070.1 - 0.57 10.0 2.7 25 4.7 0.2 2.8 2 0 0 2 2 2 0 Melon necrotic spot virus P7B protein NUDIX PF00293.23 EIW77071.1 - 1.6e-13 50.4 0.0 2e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain HLH PF00010.21 EIW77075.1 - 7e-12 44.8 0.0 1.9e-11 43.4 0.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain FA_desaturase PF00487.19 EIW77076.1 - 1.6e-26 93.3 16.1 2.5e-26 92.7 11.2 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EIW77076.1 - 6.1e-19 66.9 0.2 1e-18 66.2 0.1 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) NUDIX PF00293.23 EIW77078.1 - 2.8e-09 36.7 0.3 3.7e-09 36.3 0.2 1.4 1 1 0 1 1 1 1 NUDIX domain Terpene_synth_C PF03936.11 EIW77082.1 - 1e-08 34.7 0.0 1.5e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain FGase PF05013.7 EIW77082.1 - 0.008 16.0 0.1 0.01 15.7 0.1 1.2 1 0 0 1 1 1 1 N-formylglutamate amidohydrolase DAO PF01266.19 EIW77083.1 - 9.8e-23 80.6 0.4 3.2e-22 78.9 0.3 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW77083.1 - 2.6e-05 23.2 0.0 3.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIW77083.1 - 0.0073 16.2 0.0 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW77083.1 - 0.019 14.9 1.5 0.066 13.2 0.1 2.5 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIW77083.1 - 0.029 14.7 0.3 0.05 14.0 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EIW77083.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Thi4 PF01946.12 EIW77083.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family p450 PF00067.17 EIW77084.1 - 4.8e-76 256.1 0.0 5.8e-76 255.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acetyltransf_3 PF13302.1 EIW77088.1 - 3.9e-09 36.8 0.0 1e-08 35.4 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW77088.1 - 0.0039 17.1 0.0 0.0073 16.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EIW77088.1 - 0.0042 17.0 0.0 0.0085 16.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain HEAT PF02985.17 EIW77089.1 - 0.0003 20.6 3.2 11 6.4 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 EIW77089.1 - 0.0072 16.5 18.3 0.013 15.7 0.1 5.3 4 1 1 5 5 5 2 HEAT repeats Ded_cyto PF06920.8 EIW77089.1 - 0.046 13.0 0.0 0.17 11.1 0.0 2.0 1 0 0 1 1 1 0 Dedicator of cytokinesis NARP1 PF12569.3 EIW77090.1 - 8.9e-158 526.2 5.8 3e-157 524.5 0.5 2.6 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_11 PF13414.1 EIW77090.1 - 3.9e-14 52.0 20.4 0.00012 21.6 0.3 7.1 6 1 2 8 8 8 3 TPR repeat TPR_19 PF14559.1 EIW77090.1 - 2.2e-13 50.3 17.9 0.0015 18.8 0.1 8.3 7 1 2 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 EIW77090.1 - 1.8e-09 37.9 36.1 0.009 16.6 1.0 9.3 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIW77090.1 - 1.3e-08 34.1 26.0 0.15 12.0 0.1 9.1 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIW77090.1 - 1.5e-08 34.5 24.7 0.0041 17.6 0.6 10.1 7 3 2 10 10 10 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIW77090.1 - 7.3e-07 28.9 0.4 2.8 8.3 0.0 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EIW77090.1 - 3e-06 27.2 2.1 0.14 12.2 0.0 4.2 3 1 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.1 EIW77090.1 - 0.00078 19.2 10.6 0.064 13.1 0.0 5.6 6 0 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 EIW77090.1 - 0.0012 18.6 21.5 0.35 10.7 0.3 8.0 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIW77090.1 - 0.0025 17.4 8.1 0.21 11.4 0.0 5.6 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIW77090.1 - 0.0051 16.7 23.1 0.43 10.5 0.3 6.8 5 1 2 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIW77090.1 - 0.0075 16.6 11.1 24 5.6 0.0 7.6 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIW77090.1 - 0.012 15.1 13.1 0.56 9.9 0.1 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 EIW77090.1 - 0.049 14.0 24.5 0.45 11.0 0.0 7.6 7 0 0 7 7 7 0 Tetratricopeptide repeat SR-25 PF10500.4 EIW77090.1 - 0.056 12.9 2.8 2.1 7.7 3.1 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TPR_8 PF13181.1 EIW77090.1 - 0.1 12.4 7.5 0.62 9.9 0.0 5.0 7 0 0 7 7 5 0 Tetratricopeptide repeat Ribosomal_L44 PF00935.14 EIW77091.1 - 4.5e-35 119.5 11.2 7.3e-35 118.8 7.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 AAA_16 PF13191.1 EIW77093.1 - 1.9e-12 47.5 1.4 2.8e-12 47.0 0.9 1.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EIW77093.1 - 6.2e-12 45.4 0.0 9.2e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 NACHT domain Arch_ATPase PF01637.13 EIW77093.1 - 1.5e-06 28.0 0.0 2e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EIW77093.1 - 1.3e-05 25.3 0.0 4.1e-05 23.7 0.0 1.8 1 1 1 2 2 2 1 AAA domain APS_kinase PF01583.15 EIW77093.1 - 0.0008 19.0 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.17 EIW77093.1 - 0.0011 19.1 0.0 0.0033 17.5 0.0 1.7 2 0 0 2 2 2 1 RNA helicase PRK PF00485.13 EIW77093.1 - 0.0018 17.8 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA PF00004.24 EIW77093.1 - 0.0052 16.9 0.0 0.012 15.8 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EIW77093.1 - 0.0074 15.1 0.0 0.013 14.3 0.0 1.3 1 1 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.1 EIW77093.1 - 0.012 15.5 0.0 0.091 12.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EIW77093.1 - 0.035 13.6 0.3 0.19 11.3 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EIW77093.1 - 0.071 12.8 0.0 0.71 9.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EIW77093.1 - 0.097 12.5 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIW77093.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 EIW77093.1 - 0.14 12.9 0.0 0.47 11.2 0.0 1.9 2 1 0 2 2 2 0 AAA domain PQQ PF01011.16 EIW77094.1 - 0.0015 17.9 0.0 0.0043 16.5 0.0 1.9 1 0 0 1 1 1 1 PQQ enzyme repeat PQQ_2 PF13360.1 EIW77094.1 - 0.0052 16.2 0.3 0.11 11.9 0.0 2.9 3 0 0 3 3 3 1 PQQ-like domain Statherin PF03875.8 EIW77094.1 - 0.043 13.6 0.9 0.26 11.1 0.0 2.3 2 0 0 2 2 2 0 Statherin WD40 PF00400.27 EIW77094.1 - 0.19 11.6 5.3 93 3.1 0.0 4.9 5 0 0 5 5 5 0 WD domain, G-beta repeat HMG-CoA_red PF00368.13 EIW77096.1 - 1.7e-157 523.8 4.6 2.3e-157 523.4 3.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Sterol-sensing PF12349.3 EIW77096.1 - 2e-16 59.7 0.1 5.1e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EIW77096.1 - 2.7e-05 22.3 0.0 3.9e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Patched family Peptidase_M28 PF04389.12 EIW77097.1 - 1.1e-28 100.1 0.0 1.9e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.10 EIW77097.1 - 3.2e-05 23.2 0.0 5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Nicastrin Peptidase_M20 PF01546.23 EIW77097.1 - 6.4e-05 22.5 0.0 0.00013 21.5 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 DCP1 PF06058.8 EIW77101.1 - 2.6e-14 53.3 0.0 8.2e-14 51.7 0.0 1.8 2 0 0 2 2 2 1 Dcp1-like decapping family Macoilin PF09726.4 EIW77101.1 - 1.2 7.3 5.8 1.9 6.6 4.1 1.3 1 0 0 1 1 1 0 Transmembrane protein CMD PF02627.15 EIW77104.1 - 0.00013 21.6 0.1 0.00031 20.5 0.0 1.6 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family FAM74 PF15026.1 EIW77104.1 - 0.11 12.1 0.0 0.27 10.8 0.0 1.7 1 1 0 1 1 1 0 FAM74 protein F-box PF00646.28 EIW77105.1 - 0.0013 18.3 0.0 0.0043 16.6 0.0 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW77105.1 - 0.18 11.5 3.1 0.15 11.7 0.2 2.4 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 EIW77110.1 - 2.9e-07 29.9 0.2 6.1e-07 28.9 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW77110.1 - 4.5e-05 23.0 2.3 7.2e-05 22.4 0.2 2.4 2 0 0 2 2 2 1 F-box-like FLgD_tudor PF13861.1 EIW77110.1 - 0.1 12.6 0.0 0.3 11.1 0.0 1.7 2 0 0 2 2 2 0 FlgD Tudor-like domain TSP_C PF05735.7 EIW77110.1 - 0.12 11.9 0.1 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Thrombospondin C-terminal region DUF2353 PF09789.4 EIW77111.1 - 0.0067 15.7 6.2 0.65 9.2 0.6 2.3 2 0 0 2 2 2 2 Uncharacterized coiled-coil protein (DUF2353) YmzC PF14157.1 EIW77111.1 - 0.058 13.2 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 YmzC-like protein DUF1664 PF07889.7 EIW77111.1 - 0.15 11.8 5.6 5.8 6.7 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Mto2_bdg PF12808.2 EIW77111.1 - 0.49 10.5 0.1 0.49 10.5 0.0 2.2 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region Spc24 PF08286.6 EIW77111.1 - 2 8.1 12.9 0.043 13.5 1.4 2.7 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 CENP-Q PF13094.1 EIW77111.1 - 2.7 7.9 8.7 0.43 10.6 0.4 2.5 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Tektin PF03148.9 EIW77111.1 - 4.1 5.8 12.4 2.5 6.5 1.4 2.9 2 1 0 3 3 3 0 Tektin family CMD PF02627.15 EIW77112.1 - 8.4e-05 22.3 1.5 0.00014 21.6 0.0 2.1 2 1 0 2 2 2 1 Carboxymuconolactone decarboxylase family ADH_zinc_N PF00107.21 EIW77113.1 - 1e-15 57.4 0.0 2.4e-15 56.2 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW77113.1 - 3.6e-09 36.3 0.0 9.3e-09 35.0 0.0 1.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIW77113.1 - 8.6e-05 23.4 0.0 0.00022 22.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EIW77115.1 - 2e-14 53.2 0.0 3.2e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW77115.1 - 8.4e-08 31.9 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIW77115.1 - 0.00027 21.8 0.0 0.00055 20.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EIW77116.1 - 9.3e-17 60.7 0.1 2.1e-16 59.6 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW77116.1 - 9.4e-08 31.7 0.0 2.1e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIW77116.1 - 1.6e-06 29.0 0.0 3.2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CheB_methylest PF01339.12 EIW77116.1 - 0.064 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 CheB methylesterase Peroxin-13_N PF04088.8 EIW77117.1 - 1.1e-41 142.4 0.0 2.6e-41 141.2 0.0 1.7 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EIW77117.1 - 6.8e-09 35.0 0.0 1.5e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIW77117.1 - 2.9e-08 32.9 1.6 0.0031 16.8 1.1 2.5 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EIW77117.1 - 1.1e-06 28.1 0.0 2.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Borrelia_P83 PF05262.6 EIW77119.1 - 4.1 5.5 11.1 6.2 4.9 7.7 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein WAPL PF07814.8 EIW77120.1 - 4.8e-12 45.2 0.0 7.8e-12 44.5 0.0 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin ADH_zinc_N PF00107.21 EIW77121.1 - 8.3e-16 57.7 0.0 1.4e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW77121.1 - 1.9e-08 34.0 0.0 3e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIW77121.1 - 2.3e-06 28.4 0.0 4e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Asp PF00026.18 EIW77122.1 - 5.7e-47 160.5 17.3 1.1e-46 159.5 12.0 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW77122.1 - 3.5e-07 30.3 6.5 6.2e-06 26.2 3.3 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIW77122.1 - 1e-05 25.9 6.9 0.0012 19.3 0.7 3.0 2 1 1 3 3 3 2 Aspartyl protease gag-asp_proteas PF13975.1 EIW77122.1 - 0.12 12.2 0.4 0.8 9.5 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp PF00026.18 EIW77123.1 - 2.8e-34 118.7 17.6 1.5e-33 116.4 12.2 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW77123.1 - 1.4e-06 28.3 6.2 2.5e-06 27.5 2.3 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Lactamase_B_2 PF12706.2 EIW77124.1 - 7.2e-32 110.5 0.0 2e-31 109.0 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EIW77124.1 - 7.6e-11 41.3 0.1 2.4e-10 39.7 0.0 1.9 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 EIW77124.1 - 6.7e-10 38.9 0.0 1.3e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily MFS_1 PF07690.11 EIW77126.1 - 5.9e-19 67.9 32.2 5.9e-19 67.9 22.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Ca_hom_mod PF14798.1 EIW77126.1 - 0.1 11.5 4.1 0.12 11.3 1.1 2.1 2 0 0 2 2 2 0 Calcium homeostasis modulator HET PF06985.6 EIW77127.1 - 1.3e-19 70.7 4.0 8.1e-17 61.6 0.2 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MatE PF01554.13 EIW77128.1 - 1.4e-45 154.8 30.1 1.4e-27 96.2 5.1 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 EIW77128.1 - 1.2e-05 25.1 9.1 1.2e-05 25.1 6.3 4.2 4 1 1 5 5 5 2 Polysaccharide biosynthesis C-terminal domain Bac_surface_Ag PF01103.18 EIW77129.1 - 2.7e-37 128.9 0.0 3.3e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Surface antigen DUF3046 PF11248.3 EIW77129.1 - 0.045 13.7 0.1 1 9.3 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3046) ADH_N PF08240.7 EIW77130.1 - 1.7e-08 34.1 0.0 3.1e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW77130.1 - 9.7e-07 28.3 0.0 1.7e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW77130.1 - 0.00049 20.9 0.0 0.00077 20.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Hist_deacetyl PF00850.14 EIW77131.1 - 2.2e-59 201.2 0.0 2.9e-59 200.8 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain HET PF06985.6 EIW77132.1 - 1e-19 71.0 2.7 2.6e-16 60.0 0.1 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Transaldolase PF00923.14 EIW77133.1 - 3.3e-47 160.9 0.1 4.1e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Transaldolase SIN1 PF05422.7 EIW77134.1 - 8.6e-45 153.2 0.0 3.7e-24 85.1 0.0 2.1 2 0 0 2 2 2 2 Stress-activated map kinase interacting protein 1 (SIN1) RBD PF02196.10 EIW77134.1 - 3.4e-05 23.5 0.0 9.4e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 Raf-like Ras-binding domain TUG-UBL1 PF11470.3 EIW77134.1 - 0.00083 19.2 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 GLUT4 regulating protein TUG NOP5NT PF08156.8 EIW77135.1 - 0.097 12.8 0.0 16 5.7 0.0 3.1 3 0 0 3 3 3 0 NOP5NT (NUC127) domain DDE_Tnp_4 PF13359.1 EIW77142.1 - 0.00092 18.8 0.0 0.00092 18.8 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIW77144.1 - 8.3e-09 34.8 5.2 2.8e-06 26.6 0.0 3.5 2 2 1 4 4 4 2 DDE superfamily endonuclease DUF1681 PF07933.9 EIW77144.1 - 0.43 10.1 3.6 4.1 6.9 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1681) DDE_1 PF03184.14 EIW77145.1 - 2.3e-11 43.2 0.1 2.4e-11 43.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-CCHC PF00098.18 EIW77146.1 - 0.00028 20.6 3.7 0.00028 20.6 2.5 2.2 2 0 0 2 2 2 1 Zinc knuckle DUF2890 PF11081.3 EIW77146.1 - 0.2 11.7 1.9 0.38 10.7 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2890) Retrotrans_gag PF03732.12 EIW77147.1 - 9.6e-05 22.3 0.3 0.0002 21.3 0.2 1.6 1 0 0 1 1 1 1 Retrotransposon gag protein zf-CCHC PF00098.18 EIW77147.1 - 0.028 14.3 2.3 0.043 13.7 1.6 1.3 1 0 0 1 1 1 0 Zinc knuckle Transket_pyr PF02779.19 EIW77147.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Transketolase, pyrimidine binding domain Gag_p12 PF01141.13 EIW77147.1 - 0.13 12.4 0.0 0.38 10.9 0.0 1.8 1 1 0 1 1 1 0 Gag polyprotein, inner coat protein p12 Bac_DnaA_C PF08299.6 EIW77150.1 - 0.16 11.8 0.6 0.39 10.6 0.1 1.8 2 0 0 2 2 2 0 Bacterial dnaA protein helix-turn-helix Glyco_hydro_81 PF03639.8 EIW77154.1 - 1.1e-187 625.2 0.0 1.4e-187 624.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 IBR PF01485.16 EIW77156.1 - 2.8e-15 55.9 21.6 2.3e-09 37.0 2.9 4.5 4 1 0 4 4 4 2 IBR domain RRM_1 PF00076.17 EIW77156.1 - 2.1e-09 36.8 0.0 0.003 17.1 0.0 4.2 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_2 PF13923.1 EIW77156.1 - 3.4e-06 26.9 7.1 3.4e-06 26.9 4.9 4.5 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIW77156.1 - 1.5e-05 24.7 4.9 1.5e-05 24.7 3.4 4.2 3 2 0 3 3 2 1 zinc finger of C3HC4-type, RING RRM_6 PF14259.1 EIW77156.1 - 5.5e-05 23.0 0.0 0.0098 15.8 0.0 3.2 4 0 0 4 4 4 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 EIW77156.1 - 5.7e-05 22.6 6.0 5.7e-05 22.6 4.2 4.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW77156.1 - 9.2e-05 22.1 6.6 9.2e-05 22.1 4.6 4.3 2 1 1 3 3 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIW77156.1 - 0.00027 20.5 5.5 0.00027 20.5 3.8 3.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIW77156.1 - 0.00061 19.4 2.6 0.00061 19.4 1.8 2.9 3 0 0 3 3 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 EIW77156.1 - 0.0025 17.5 6.4 0.0025 17.5 4.4 3.7 3 0 0 3 3 2 1 zinc-RING finger domain RRM_5 PF13893.1 EIW77156.1 - 0.0028 17.4 0.0 3.7 7.4 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 EIW77156.1 - 0.042 13.6 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif GST_N_3 PF13417.1 EIW77157.1 - 5.6e-12 45.7 0.0 1.4e-11 44.4 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW77157.1 - 2e-11 43.9 0.0 4e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW77157.1 - 2.5e-08 33.7 0.0 5.4e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW77157.1 - 0.00046 20.0 0.0 0.0007 19.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW77157.1 - 0.013 15.4 0.0 0.024 14.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW77157.1 - 0.023 15.1 0.0 0.034 14.6 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Mitochondr_Som1 PF11093.3 EIW77159.1 - 1.8e-06 27.6 0.2 2.4e-06 27.2 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 AdoHcyase PF05221.12 EIW77160.1 - 7.9e-139 461.1 0.1 8.9e-139 460.9 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EIW77160.1 - 5.4e-85 283.2 1.3 7.9e-85 282.6 0.9 1.2 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EIW77160.1 - 5.7e-09 35.3 0.1 1.2e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EIW77160.1 - 8.4e-05 22.0 0.1 0.00013 21.3 0.1 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EIW77160.1 - 0.00049 20.0 0.1 0.0011 18.8 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 EIW77160.1 - 0.016 14.8 0.1 0.027 14.0 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase F420_oxidored PF03807.12 EIW77160.1 - 0.021 15.2 0.1 0.056 13.8 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 EIW77160.1 - 0.057 13.3 1.4 3.6 7.4 0.1 2.7 2 0 0 2 2 2 0 short chain dehydrogenase La PF05383.12 EIW77162.1 - 1.9e-17 62.7 0.0 3.1e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 La domain Pmp3 PF01679.12 EIW77163.1 - 7.2e-20 70.4 7.5 8.7e-20 70.1 5.2 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator SpoVIF PF14069.1 EIW77164.1 - 0.12 12.1 0.4 0.21 11.3 0.3 1.4 1 0 0 1 1 1 0 Stage VI sporulation protein F Nol1_Nop2_Fmu PF01189.12 EIW77165.1 - 9.2e-29 100.6 0.0 6.5e-27 94.6 0.0 2.3 2 0 0 2 2 2 2 NOL1/NOP2/sun family FtsJ PF01728.14 EIW77165.1 - 0.02 14.8 0.0 0.041 13.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase MutS_V PF00488.16 EIW77166.1 - 1.8e-98 328.6 0.0 2.6e-98 328.1 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EIW77166.1 - 1.4e-32 113.1 2.2 1.9e-32 112.7 0.3 2.0 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 EIW77166.1 - 5.5e-17 61.7 1.0 1.5e-16 60.3 0.7 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EIW77166.1 - 1.5e-16 60.6 0.0 2e-15 57.0 0.0 2.5 2 0 0 2 2 2 1 MutS domain II MutS_I PF01624.15 EIW77166.1 - 2.8e-10 40.2 0.0 9.8e-10 38.4 0.0 2.0 2 0 0 2 2 2 1 MutS domain I AAA_23 PF13476.1 EIW77166.1 - 8.4 6.6 10.4 21 5.3 2.2 3.2 3 0 0 3 3 3 0 AAA domain RAP1 PF07218.6 EIW77167.1 - 1.2 7.1 12.3 1.6 6.7 8.5 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) p450 PF00067.17 EIW77168.1 - 5.9e-66 222.8 0.0 6.9e-66 222.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 EIW77169.1 - 1.6e-86 290.7 25.7 1.8e-86 290.5 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW77169.1 - 6.9e-20 71.0 45.1 1.3e-18 66.8 17.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIW77169.1 - 3.6e-07 28.9 23.7 5.4e-05 21.7 2.2 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein DUF2235 PF09994.4 EIW77170.1 - 1.5e-22 80.3 0.0 1.9e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF2235 PF09994.4 EIW77171.1 - 1.4e-16 60.7 0.4 1.7e-16 60.4 0.3 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) APG6 PF04111.7 EIW77173.1 - 0.00062 18.9 2.3 0.00075 18.6 1.6 1.0 1 0 0 1 1 1 1 Autophagy protein Apg6 Myosin_tail_1 PF01576.14 EIW77173.1 - 0.012 13.3 1.9 0.014 13.1 1.3 1.0 1 0 0 1 1 1 0 Myosin tail BicD PF09730.4 EIW77173.1 - 0.014 13.8 2.1 0.015 13.6 1.4 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D DUF4201 PF13870.1 EIW77173.1 - 0.024 14.0 1.3 0.032 13.6 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) AcylCoA_dehyd_C PF12186.3 EIW77173.1 - 0.044 13.6 2.6 0.38 10.6 0.1 2.1 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase C terminal Dict-STAT-coil PF09267.5 EIW77173.1 - 0.045 13.9 0.2 0.081 13.1 0.1 1.4 1 0 0 1 1 1 0 Dictyostelium STAT, coiled coil Exonuc_VII_L PF02601.10 EIW77173.1 - 0.058 12.5 1.3 0.096 11.8 0.1 1.7 1 1 1 2 2 2 0 Exonuclease VII, large subunit CENP-F_leu_zip PF10473.4 EIW77173.1 - 0.08 12.8 0.7 0.21 11.4 0.3 1.6 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YqeY PF09424.5 EIW77173.1 - 0.089 12.6 1.5 0.1 12.4 1.0 1.1 1 0 0 1 1 1 0 Yqey-like protein GAS PF13851.1 EIW77173.1 - 0.093 11.9 1.5 0.13 11.4 1.0 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding FliJ PF02050.11 EIW77173.1 - 0.11 12.5 6.1 0.1 12.6 2.0 1.9 1 1 1 2 2 2 0 Flagellar FliJ protein IncA PF04156.9 EIW77173.1 - 0.2 11.2 2.6 0.26 10.8 1.8 1.1 1 0 0 1 1 1 0 IncA protein Fmp27_WPPW PF10359.4 EIW77173.1 - 0.23 9.8 2.3 0.26 9.6 1.6 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Suppressor_APC PF11414.3 EIW77173.1 - 0.44 10.3 3.2 0.59 9.9 1.4 1.8 1 1 1 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein SlyX PF04102.7 EIW77173.1 - 0.52 10.7 4.0 0.62 10.4 1.9 1.8 1 1 0 1 1 1 0 SlyX bcl-2I13 PF12201.3 EIW77174.1 - 0.16 11.4 0.0 0.91 8.9 0.0 2.0 2 0 0 2 2 2 0 Bcl2-interacting killer, BH3-domain containing Mito_carr PF00153.22 EIW77176.1 - 5.2e-58 192.7 0.1 2.5e-22 78.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Sugar_tr PF00083.19 EIW77177.1 - 5.5e-85 285.6 20.3 6.3e-85 285.4 14.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW77177.1 - 2.8e-19 69.0 27.4 8.4e-18 64.1 14.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIW77177.1 - 4e-09 35.3 19.9 8.4e-05 21.1 2.8 3.6 3 1 1 4 4 4 3 MFS/sugar transport protein DUF2417 PF10329.4 EIW77177.1 - 1.9 7.8 6.0 0.63 9.4 1.9 1.8 3 0 0 3 3 3 0 Region of unknown function (DUF2417) Sds3 PF08598.6 EIW77178.1 - 0.016 14.7 0.9 0.016 14.7 0.6 2.2 2 0 0 2 2 2 0 Sds3-like DUF904 PF06005.7 EIW77178.1 - 0.29 11.4 15.8 5 7.4 2.2 3.9 3 1 0 3 3 3 0 Protein of unknown function (DUF904) ADH_zinc_N PF00107.21 EIW77180.1 - 7.2e-12 44.9 0.2 1.3e-11 44.1 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW77180.1 - 4e-07 29.7 0.0 6.6e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIW77180.1 - 2.1e-05 25.3 0.5 5.5e-05 24.0 0.3 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EIW77180.1 - 0.095 12.7 1.1 0.15 12.0 0.7 1.4 1 0 0 1 1 1 0 NADH(P)-binding Sugar_tr PF00083.19 EIW77181.1 - 1.1e-80 271.4 21.5 1.3e-80 271.2 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW77181.1 - 7.3e-15 54.5 33.3 2.4e-12 46.2 17.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIW77181.1 - 3.8e-07 28.8 22.7 0.00046 18.6 7.8 3.2 3 1 1 4 4 4 2 MFS/sugar transport protein Pro_racemase PF05544.6 EIW77181.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 Proline racemase ADH_zinc_N PF00107.21 EIW77182.1 - 1.2e-09 37.7 0.1 2.3e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW77182.1 - 9.1e-08 31.8 0.0 1.5e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIW77182.1 - 0.00017 22.4 0.0 0.00036 21.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.16 EIW77182.1 - 0.0083 15.5 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2235 PF09994.4 EIW77184.1 - 9e-18 64.6 0.3 9.6e-18 64.5 0.2 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) zf-Di19 PF05605.7 EIW77185.1 - 0.0012 18.8 1.2 0.0012 18.8 0.8 2.1 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding PTS-HPr PF00381.14 EIW77187.1 - 0.034 14.0 0.0 0.043 13.7 0.0 1.2 1 0 0 1 1 1 0 PTS HPr component phosphorylation site CaATP_NAI PF12515.3 EIW77189.1 - 4.8 6.7 6.6 2.4 7.7 2.3 2.2 2 0 0 2 2 2 0 Ca2+-ATPase N terminal autoinhibitory domain DUF2034 PF10356.4 EIW77190.1 - 6.8e-29 100.3 0.3 2e-14 53.1 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EIW77190.1 - 6.1e-06 26.0 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Restriction endonuclease RRF PF01765.14 EIW77191.1 - 2.6e-27 95.2 0.3 4.8e-27 94.4 0.2 1.4 1 0 0 1 1 1 1 Ribosome recycling factor SNF2_N PF00176.18 EIW77192.1 - 9.3e-65 218.3 0.1 1.4e-64 217.7 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW77192.1 - 6.2e-11 42.0 0.1 1.2e-09 37.9 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EIW77192.1 - 4.1e-09 35.9 4.9 7.9e-09 35.0 3.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW77192.1 - 9.2e-09 35.1 5.0 2.1e-08 34.0 3.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW77192.1 - 1.8e-07 30.8 7.6 3.5e-07 29.9 5.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIW77192.1 - 6e-07 29.0 6.0 1.1e-06 28.2 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIW77192.1 - 4.6e-06 26.2 1.5 1.1e-05 25.0 1.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EIW77192.1 - 9.2e-06 25.4 3.5 2.4e-05 24.1 2.4 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING ResIII PF04851.10 EIW77192.1 - 1.4e-05 25.0 0.0 3.6e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-RING_5 PF14634.1 EIW77192.1 - 0.00037 20.1 7.6 0.00073 19.2 5.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.3 EIW77192.1 - 0.014 14.9 4.1 0.028 13.9 2.8 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Vps39_2 PF10367.4 EIW77192.1 - 0.14 12.3 1.6 0.75 10.0 0.3 2.9 2 1 0 2 2 1 0 Vacuolar sorting protein 39 domain 2 AA_permease_2 PF13520.1 EIW77193.1 - 2.3e-66 224.1 43.5 2.8e-66 223.8 30.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIW77193.1 - 8e-08 31.0 39.6 1.4e-07 30.2 26.4 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIW77194.1 - 2.5e-73 247.0 40.7 3.2e-73 246.7 28.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIW77194.1 - 9.2e-16 57.2 34.1 1.6e-15 56.4 23.6 1.3 1 0 0 1 1 1 1 Amino acid permease TruD PF01142.13 EIW77194.1 - 0.085 11.5 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 tRNA pseudouridine synthase D (TruD) ABC_membrane_2 PF06472.10 EIW77195.1 - 3.6e-78 262.5 0.3 6.2e-78 261.7 0.2 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EIW77195.1 - 2.2e-17 63.6 0.0 5.1e-17 62.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter Sigma54_activ_2 PF14532.1 EIW77195.1 - 0.037 14.0 0.0 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.1 EIW77195.1 - 0.066 13.5 0.0 2.4 8.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EIW77195.1 - 0.087 12.2 0.0 0.39 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain F-box PF00646.28 EIW77196.1 - 0.055 13.1 0.0 0.18 11.5 0.0 1.9 1 0 0 1 1 1 0 F-box domain ADH_zinc_N PF00107.21 EIW77197.1 - 7.1e-15 54.6 0.1 1.2e-14 53.9 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW77197.1 - 1.1e-09 38.0 1.0 1.2e-08 34.7 0.4 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIW77197.1 - 8.5e-05 23.4 0.0 0.00014 22.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FA_desaturase PF00487.19 EIW77198.1 - 8.7e-15 54.8 20.8 1.5e-14 54.1 14.4 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EIW77198.1 - 3.9e-13 49.0 0.0 7.9e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-RING_5 PF14634.1 EIW77199.1 - 9.1e-05 22.1 8.7 0.00018 21.1 6.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain RRM_6 PF14259.1 EIW77199.1 - 0.0022 17.9 0.0 0.0055 16.6 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4 PF00097.20 EIW77199.1 - 0.01 15.4 9.0 0.021 14.4 6.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS91 PF14319.1 EIW77199.1 - 0.017 14.6 2.7 0.04 13.4 1.8 1.6 1 0 0 1 1 1 0 Transposase zinc-binding domain RRM_1 PF00076.17 EIW77199.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 EIW77199.1 - 1 9.2 8.3 2.4 8.0 5.7 1.6 1 0 0 1 1 1 0 Ring finger domain F-box-like PF12937.2 EIW77200.1 - 0.0012 18.5 1.3 0.0045 16.6 0.1 2.6 3 0 0 3 3 3 1 F-box-like Pyridox_oxidase PF01243.15 EIW77201.1 - 0.00027 20.8 0.0 0.26 11.3 0.0 2.7 2 1 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase DUF1482 PF07358.6 EIW77201.1 - 0.0021 17.5 0.1 2.4 7.8 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1482) DUF1275 PF06912.6 EIW77201.1 - 0.11 11.7 0.5 4.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1275) MOR2-PAG1_N PF14222.1 EIW77202.1 - 5.6e-134 447.8 0.5 1.6e-133 446.3 0.0 2.0 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EIW77202.1 - 7.9e-62 209.3 0.8 2.3e-61 207.8 0.6 1.8 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EIW77202.1 - 1.5e-12 46.0 0.6 4e-09 34.6 0.0 3.1 3 0 0 3 3 3 2 Cell morphogenesis central region DNA_mis_repair PF01119.14 EIW77203.1 - 2.6e-29 101.1 0.0 4.6e-29 100.2 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EIW77203.1 - 2.2e-12 46.8 0.0 6.2e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EIW77203.1 - 1.7e-11 43.7 0.0 4.5e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ADH_zinc_N PF00107.21 EIW77204.1 - 1.7e-15 56.7 0.0 3.9e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW77204.1 - 4.5e-09 36.0 0.1 1.2e-08 34.7 0.0 1.7 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIW77204.1 - 3.9e-05 24.5 0.0 8.1e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EIW77205.1 - 3.4e-16 58.9 0.1 5.6e-16 58.2 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW77205.1 - 7.7e-10 38.4 0.0 5.3e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIW77205.1 - 6e-06 27.1 0.0 1.1e-05 26.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NmrA PF05368.8 EIW77205.1 - 0.0036 16.5 0.5 0.0061 15.8 0.4 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIW77205.1 - 0.0057 16.6 0.4 0.0085 16.1 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding AlaDh_PNT_C PF01262.16 EIW77205.1 - 0.0065 16.0 1.2 0.16 11.5 0.1 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Semialdhyde_dh PF01118.19 EIW77205.1 - 0.023 15.0 0.1 0.045 14.0 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain PC_rep PF01851.17 EIW77206.1 - 1.2e-21 75.6 17.4 2.5e-05 24.2 0.2 8.8 8 0 0 8 8 8 4 Proteasome/cyclosome repeat OAD_gamma PF04277.8 EIW77206.1 - 3.9 7.9 8.5 0.66 10.3 0.0 2.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Sigma70_ner PF04546.8 EIW77206.1 - 4.8 6.7 16.5 1.4 8.5 1.0 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region FAM176 PF14851.1 EIW77206.1 - 7.6 6.2 10.8 3.1 7.4 0.4 2.4 2 0 0 2 2 2 0 FAM176 family DSPc PF00782.15 EIW77207.1 - 0.00034 20.2 0.0 0.0007 19.1 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EIW77207.1 - 0.018 15.3 0.0 0.058 13.6 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family Y_phosphatase PF00102.22 EIW77207.1 - 0.059 12.6 0.0 0.097 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EIW77207.1 - 0.12 12.4 0.0 0.44 10.5 0.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate CBS PF00571.23 EIW77209.1 - 3.6e-08 33.0 0.0 6.3e-05 22.6 0.0 2.5 2 1 0 2 2 2 2 CBS domain Cyclin_N PF00134.18 EIW77210.1 - 2e-46 156.7 0.7 3e-45 152.8 0.3 2.3 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EIW77210.1 - 2.7e-25 88.5 0.0 6.1e-25 87.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain tRNA-synt_1 PF00133.17 EIW77211.1 - 1.4e-152 508.8 0.0 1.8e-152 508.4 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EIW77211.1 - 1.1e-26 93.4 0.0 2.4e-26 92.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EIW77211.1 - 1.2e-24 86.7 0.4 2e-16 59.6 0.1 3.5 3 1 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.9 EIW77211.1 - 8.5e-06 25.2 4.2 1.6e-05 24.3 2.9 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.14 EIW77211.1 - 0.00073 18.7 0.0 0.0082 15.3 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.13 EIW77211.1 - 0.022 13.4 0.1 0.49 9.0 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) tRNA-synt_1d PF00750.14 EIW77211.1 - 0.11 11.2 0.1 2.8 6.6 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (R) Pkinase_Tyr PF07714.12 EIW77212.1 - 1.1e-23 83.6 0.0 3.9e-23 81.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EIW77212.1 - 1.1e-19 70.6 0.0 1.5e-18 66.9 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW77213.1 - 1.2e-40 139.2 0.0 1.8e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EIW77213.1 - 1.2e-37 129.5 0.0 1.7e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EIW77213.1 - 2.5e-05 23.3 0.0 4.1e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW77213.1 - 0.0015 18.2 0.3 0.021 14.5 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EIW77213.1 - 0.19 10.7 0.0 0.48 9.4 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EIW77213.1 - 0.23 10.7 0.0 0.4 9.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family ProRS-C_1 PF09180.6 EIW77214.1 - 1.9e-24 85.3 0.7 5.2e-24 83.9 0.5 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.20 EIW77214.1 - 3.9e-20 72.1 0.1 6.7e-20 71.3 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EIW77214.1 - 5.4e-16 58.3 0.0 1.3e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA_edit PF04073.10 EIW77214.1 - 5.9e-11 42.2 0.0 9.5e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain Sugar_tr PF00083.19 EIW77215.1 - 1.5e-105 353.3 20.6 1.8e-105 353.1 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW77215.1 - 7.5e-20 70.9 37.0 1.2e-13 50.4 8.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ADH_N PF08240.7 EIW77216.1 - 8.6e-28 96.2 2.1 2.1e-27 95.0 1.5 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW77216.1 - 2.5e-17 62.6 0.0 4.1e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW77216.1 - 0.00013 22.8 0.0 0.0003 21.7 0.0 1.6 1 1 1 2 2 2 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 EIW77216.1 - 0.00028 20.0 0.7 0.0004 19.5 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.15 EIW77216.1 - 0.0035 17.4 0.1 0.0071 16.4 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_3 PF03447.11 EIW77216.1 - 0.0081 16.5 0.1 0.014 15.8 0.0 1.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EIW77216.1 - 0.018 15.2 0.1 0.034 14.3 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_8 PF13450.1 EIW77216.1 - 0.12 12.4 0.6 0.24 11.4 0.4 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF2338 PF10100.4 EIW77216.1 - 0.12 10.6 0.0 0.2 10.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) 3Beta_HSD PF01073.14 EIW77217.1 - 1.3e-25 89.6 0.0 1e-24 86.7 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIW77217.1 - 2.5e-13 50.0 0.0 4.1e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EIW77217.1 - 3.9e-10 39.0 0.0 4.7e-08 32.2 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EIW77217.1 - 1.6e-05 25.0 0.0 6.9e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EIW77217.1 - 0.00023 21.1 0.0 0.00051 19.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EIW77217.1 - 0.00061 18.7 0.0 0.05 12.5 0.0 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.5 EIW77217.1 - 0.0092 15.6 0.0 0.034 13.8 0.0 1.9 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EIW77217.1 - 0.022 13.6 0.0 0.039 12.8 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DJ-1_PfpI PF01965.19 EIW77218.1 - 1.1e-20 73.5 0.0 1.6e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EIW77218.1 - 2.7e-11 43.0 0.0 3.2e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase AMP-binding PF00501.23 EIW77219.1 - 1.4e-73 247.6 0.0 2e-73 247.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EIW77219.1 - 1.1e-67 227.5 0.0 2.6e-67 226.3 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EIW77219.1 - 5.9e-14 52.0 0.0 1.7e-13 50.5 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EIW77219.1 - 4.6e-10 39.3 0.0 9.3e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AMP-binding_C PF13193.1 EIW77219.1 - 6.1e-09 36.6 0.0 3.2e-08 34.4 0.0 2.4 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 EIW77219.1 - 3.1e-05 22.8 0.0 9.8e-05 21.1 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EIW77219.1 - 0.014 15.2 0.5 0.66 9.8 0.1 2.5 2 0 0 2 2 2 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EIW77219.1 - 0.019 13.8 0.0 0.063 12.1 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Condensation PF00668.15 EIW77219.1 - 0.086 11.6 0.0 0.19 10.5 0.0 1.5 1 0 0 1 1 1 0 Condensation domain Mito_carr PF00153.22 EIW77220.1 - 1.2e-56 188.4 0.9 3e-22 78.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein ADH_N PF08240.7 EIW77221.1 - 5.7e-32 109.7 0.9 1e-31 108.8 0.6 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW77221.1 - 2.5e-14 52.9 0.0 3.7e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 EIW77221.1 - 0.00088 18.4 0.9 0.0013 17.8 0.6 1.2 1 0 0 1 1 1 1 FAD binding domain ADH_zinc_N_2 PF13602.1 EIW77221.1 - 0.0022 18.8 0.0 0.0044 17.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2338 PF10100.4 EIW77221.1 - 0.017 13.5 0.0 0.024 13.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) NAD_binding_7 PF13241.1 EIW77221.1 - 0.057 13.6 0.0 0.1 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF1514 PF07438.6 EIW77221.1 - 0.069 13.0 0.0 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) ADH_N_assoc PF13823.1 EIW77221.1 - 0.077 12.6 0.6 0.16 11.6 0.0 1.8 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-associated Shikimate_DH PF01488.15 EIW77221.1 - 0.1 12.6 0.1 0.21 11.6 0.1 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase His_Phos_2 PF00328.17 EIW77222.1 - 4.3e-29 101.9 0.0 8.6e-29 100.9 0.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) AAA_16 PF13191.1 EIW77224.1 - 4.7e-08 33.2 1.4 1.3e-07 31.8 0.2 2.1 1 1 1 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EIW77224.1 - 7.2e-05 22.4 0.0 0.00017 21.2 0.0 1.7 1 1 0 1 1 1 1 NACHT domain APS_kinase PF01583.15 EIW77224.1 - 8.2e-05 22.3 0.1 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase Arch_ATPase PF01637.13 EIW77224.1 - 0.0014 18.4 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EIW77224.1 - 0.0016 18.5 0.0 0.008 16.3 0.0 2.2 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIW77224.1 - 0.0056 16.8 0.0 0.016 15.3 0.0 1.8 2 0 0 2 2 1 1 RNA helicase DUF2075 PF09848.4 EIW77224.1 - 0.0089 15.0 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 EIW77224.1 - 0.0094 15.6 0.0 2.7 7.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) T2SE PF00437.15 EIW77224.1 - 0.0097 14.8 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 EIW77224.1 - 0.019 14.5 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EIW77224.1 - 0.029 14.0 0.0 0.055 13.1 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CoaE PF01121.15 EIW77224.1 - 0.035 13.4 0.0 0.066 12.6 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase KTI12 PF08433.5 EIW77224.1 - 0.042 13.0 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NTPase_1 PF03266.10 EIW77224.1 - 0.063 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 NTPase ArgK PF03308.11 EIW77224.1 - 0.083 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Zot PF05707.7 EIW77224.1 - 0.086 12.3 0.0 0.45 9.9 0.0 1.9 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) AAA PF00004.24 EIW77224.1 - 0.095 12.9 0.0 1.2 9.2 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EIW77224.1 - 0.14 11.6 0.0 0.35 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PhoH PF02562.11 EIW77224.1 - 0.14 11.3 0.0 0.4 9.8 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein AMP-binding PF00501.23 EIW77226.1 - 2.3e-78 263.4 0.0 2.9e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIW77226.1 - 1.5e-08 35.4 0.0 4.1e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PUD PF03714.9 EIW77226.1 - 0.044 13.9 0.1 0.092 12.8 0.1 1.5 1 0 0 1 1 1 0 Bacterial pullanase-associated domain Cyt-b5 PF00173.23 EIW77227.1 - 1.3e-22 79.3 0.3 2.6e-22 78.4 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EIW77227.1 - 2.1e-08 34.5 20.5 2.1e-08 34.5 14.2 2.0 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily MFS_1 PF07690.11 EIW77228.1 - 1e-27 96.7 24.4 1e-27 96.7 16.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW77228.1 - 8.4e-08 31.2 1.9 8.4e-08 31.2 1.3 2.8 2 1 0 2 2 2 2 Sugar (and other) transporter Gti1_Pac2 PF09729.4 EIW77229.1 - 1.2e-27 96.8 0.0 2.4e-23 82.8 0.0 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family FAD_binding_7 PF03441.9 EIW77230.1 - 3.3e-89 298.7 0.0 4.3e-89 298.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EIW77230.1 - 7.7e-36 123.3 0.0 1.3e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase DUF155 PF02582.9 EIW77231.1 - 2e-55 187.3 0.1 3.1e-55 186.7 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Sec5 PF15469.1 EIW77232.1 - 4.5e-54 182.9 0.0 3.1e-53 180.2 0.0 2.2 2 0 0 2 2 2 1 Exocyst complex component Sec5 Aldo_ket_red PF00248.16 EIW77233.1 - 5.7e-42 143.4 0.0 8.1e-42 142.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Patatin PF01734.17 EIW77236.1 - 2.3e-19 70.1 0.1 1.3e-18 67.6 0.1 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase TPR_10 PF13374.1 EIW77237.1 - 2.9e-52 173.2 1.4 1.3e-13 50.3 0.0 4.0 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 EIW77237.1 - 1.9e-46 155.8 8.7 2.1e-18 66.0 0.1 2.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EIW77237.1 - 1e-20 71.7 5.4 5.8e-05 22.5 0.0 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 EIW77237.1 - 1.5e-15 56.0 6.3 0.014 15.0 0.0 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 EIW77237.1 - 1.9e-15 56.2 15.4 1e-05 25.0 0.4 3.1 1 1 3 4 4 4 4 TPR repeat TPR_3 PF07720.7 EIW77237.1 - 2.9e-14 52.4 9.8 0.0011 18.7 0.1 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 EIW77237.1 - 2.5e-12 45.9 2.6 0.037 14.2 0.0 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_4 PF07721.9 EIW77237.1 - 4.4e-12 45.1 0.7 0.051 14.0 0.1 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.1 EIW77237.1 - 1e-10 41.9 7.0 2e-05 25.1 0.2 3.5 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIW77237.1 - 3e-10 40.2 7.3 0.00048 20.4 0.5 3.2 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIW77237.1 - 2.6e-09 36.2 7.9 0.33 10.9 0.1 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.1 EIW77237.1 - 1.1e-07 31.8 8.1 0.28 11.9 0.1 4.3 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIW77237.1 - 1.6e-07 30.5 5.0 0.94 9.4 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat Apc3 PF12895.2 EIW77237.1 - 4e-06 26.8 0.8 0.002 18.2 0.2 3.0 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EIW77237.1 - 0.00013 22.2 13.4 1.9 9.1 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat Rab5-bind PF09311.6 EIW77237.1 - 0.00019 21.3 0.2 0.47 10.3 0.1 2.9 1 1 2 3 3 3 1 Rabaptin-like protein DUF1738 PF08401.6 EIW77237.1 - 0.002 17.8 0.3 11 5.7 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF1738) HSA PF07529.8 EIW77237.1 - 0.0031 17.2 0.1 8.5 6.2 0.0 3.4 4 0 0 4 4 4 0 HSA DUF1897 PF09005.5 EIW77237.1 - 0.016 14.6 4.2 4.5 6.8 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1897) LEA_5 PF00477.12 EIW77237.1 - 0.02 15.1 0.7 13 6.1 0.1 2.8 1 1 2 3 3 3 0 Small hydrophilic plant seed protein Calici_PP_N PF08405.6 EIW77237.1 - 0.063 12.0 0.0 5.1 5.8 0.0 2.3 1 1 2 3 3 3 0 Viral polyprotein N-terminal TPR_20 PF14561.1 EIW77237.1 - 0.36 10.9 4.0 7.7 6.7 0.2 3.1 1 1 2 3 3 3 0 Tetratricopeptide repeat MbeB_N PF04837.7 EIW77237.1 - 1.5 8.9 7.8 8.2 6.6 0.1 4.1 4 1 0 4 4 4 0 MbeB-like, N-term conserved region Spc7 PF08317.6 EIW77238.1 - 0.019 13.6 5.3 0.033 12.8 3.6 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.6 EIW77238.1 - 0.13 12.7 5.7 3.9 7.9 0.5 2.9 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Med9 PF07544.8 EIW77238.1 - 0.37 10.5 4.4 1.9 8.2 1.3 2.7 1 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 V_ATPase_I PF01496.14 EIW77238.1 - 0.54 8.0 3.1 0.75 7.5 2.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMCO5 PF14992.1 EIW77238.1 - 0.72 8.9 7.3 1.1 8.2 5.0 1.2 1 0 0 1 1 1 0 TMCO5 family CENP-F_leu_zip PF10473.4 EIW77238.1 - 4.3 7.1 15.8 17 5.2 10.9 2.0 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CorA PF01544.13 EIW77238.1 - 4.5 6.2 4.8 12 4.7 3.3 1.7 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein AAA_13 PF13166.1 EIW77238.1 - 6.3 5.1 7.2 15 3.8 5.0 1.5 1 1 0 1 1 1 0 AAA domain DUF3138 PF11336.3 EIW77238.1 - 8 4.5 14.7 0.31 9.1 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) XhlA PF10779.4 EIW77238.1 - 8.6 6.3 8.2 4.5 7.2 1.3 2.5 2 0 0 2 2 2 0 Haemolysin XhlA YlqD PF11068.3 EIW77238.1 - 9.6 6.2 14.4 1.1 9.3 2.1 2.8 3 0 0 3 3 3 0 YlqD protein DUF3395 PF11875.3 EIW77239.1 - 3.1e-24 85.3 0.0 4.7e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 EIW77239.1 - 2.1e-15 56.2 1.1 2.2e-15 56.1 0.1 1.6 2 0 0 2 2 2 1 DnaJ domain SURF4 PF02077.10 EIW77240.1 - 6.3e-94 314.2 6.8 7.7e-94 313.9 4.7 1.0 1 0 0 1 1 1 1 SURF4 family DUF1129 PF06570.6 EIW77240.1 - 5.9 6.1 6.5 1.1 8.4 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1129) NUC153 PF08159.7 EIW77241.1 - 2.1e-13 49.6 0.2 4.3e-13 48.5 0.1 1.6 1 0 0 1 1 1 1 NUC153 domain DUF2229 PF09989.4 EIW77241.1 - 0.83 9.0 1.5 1.4 8.3 1.0 1.2 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) Hid1 PF12722.2 EIW77241.1 - 5.1 4.6 6.5 7.7 4.0 4.5 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MIP-T3 PF10243.4 EIW77241.1 - 6.4 5.1 31.6 12 4.2 21.9 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 SAPS PF04499.10 EIW77241.1 - 8.2 4.9 11.2 13 4.2 7.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Selenoprotein_S PF06936.6 EIW77242.1 - 0.0054 16.2 0.4 0.0069 15.9 0.3 1.1 1 0 0 1 1 1 1 Selenoprotein S (SelS) Atrophin-1 PF03154.10 EIW77242.1 - 1.9 6.4 6.7 2.4 6.1 4.6 1.1 1 0 0 1 1 1 0 Atrophin-1 family PAP2 PF01569.16 EIW77244.1 - 5.9e-05 22.7 2.9 8.8e-05 22.1 2.0 1.2 1 0 0 1 1 1 1 PAP2 superfamily Me-amine-dh_L PF02975.9 EIW77244.1 - 0.031 14.2 0.5 0.045 13.7 0.4 1.3 1 0 0 1 1 1 0 Methylamine dehydrogenase, L chain Kinocilin PF15033.1 EIW77244.1 - 0.12 11.8 0.1 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Kinocilin protein DDE_3 PF13358.1 EIW77245.1 - 4.7e-05 23.1 0.0 5e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease TPR_10 PF13374.1 EIW77246.1 - 2.3e-75 246.5 2.1 6.3e-11 41.8 0.0 7.0 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.1 EIW77246.1 - 1.4e-72 239.5 23.3 3.4e-18 65.3 0.1 5.0 2 1 4 6 6 6 6 Tetratricopeptide repeat TPR_16 PF13432.1 EIW77246.1 - 3.7e-20 72.0 3.2 0.0003 21.3 0.0 4.6 1 1 3 5 5 5 4 Tetratricopeptide repeat TPR_3 PF07720.7 EIW77246.1 - 1.9e-17 62.6 12.5 0.014 15.1 0.2 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 EIW77246.1 - 5.6e-17 61.1 5.8 2.4e-05 23.9 0.3 4.5 1 1 5 6 6 6 6 TPR repeat TPR_7 PF13176.1 EIW77246.1 - 1.5e-16 58.8 11.7 0.0083 15.8 0.0 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.23 EIW77246.1 - 1.9e-13 49.3 10.1 0.021 14.4 0.1 7.0 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_4 PF07721.9 EIW77246.1 - 1.2e-12 46.9 8.8 0.1 13.0 0.1 6.5 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EIW77246.1 - 5e-12 44.7 13.3 0.04 13.8 0.1 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIW77246.1 - 7.4e-11 42.2 17.2 5.8e-06 26.5 1.9 4.9 2 2 3 5 5 5 4 Tetratricopeptide repeat Apc3 PF12895.2 EIW77246.1 - 6.1e-09 35.8 2.5 0.0045 17.0 0.1 4.5 1 1 2 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EIW77246.1 - 1.7e-08 34.3 17.2 0.22 12.2 0.7 6.7 3 2 4 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIW77246.1 - 4.4e-08 32.7 6.4 2 8.8 0.1 6.6 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIW77246.1 - 1.4e-07 30.7 6.6 0.73 9.7 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat Coatomer_E PF04733.9 EIW77246.1 - 0.00041 19.6 2.2 1.4 8.0 0.0 3.8 1 1 2 4 4 4 2 Coatomer epsilon subunit TPR_6 PF13174.1 EIW77246.1 - 0.00072 19.8 18.6 0.24 11.9 0.5 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.1 EIW77246.1 - 0.0031 17.5 9.1 0.84 9.7 0.1 5.3 2 2 3 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.4 EIW77246.1 - 0.004 17.0 10.0 0.12 12.2 0.1 4.0 1 1 1 3 3 3 1 Tetratricopeptide repeat Rab5-bind PF09311.6 EIW77246.1 - 0.025 14.4 1.8 0.64 9.8 0.2 2.7 1 1 3 4 4 4 0 Rabaptin-like protein SPOB_a PF14689.1 EIW77246.1 - 0.056 13.0 4.6 11 5.7 0.0 4.9 6 0 0 6 6 6 0 Sensor_kinase_SpoOB-type, alpha-helical domain YfdX PF10938.3 EIW77246.1 - 0.51 9.9 6.7 1.1 8.8 0.2 3.9 4 1 0 5 5 5 0 YfdX protein Patatin PF01734.17 EIW77247.1 - 8.1e-15 55.2 0.5 7.3e-08 32.5 0.1 2.2 1 1 1 2 2 2 2 Patatin-like phospholipase Amidase PF01425.16 EIW77248.1 - 5.9e-87 292.3 0.0 6.9e-87 292.1 0.0 1.0 1 0 0 1 1 1 1 Amidase Fez1 PF06818.10 EIW77250.1 - 0.0018 18.3 3.1 0.0028 17.7 2.1 1.1 1 0 0 1 1 1 1 Fez1 Cortex-I_coil PF09304.5 EIW77250.1 - 0.018 15.1 0.6 0.033 14.2 0.4 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil Filament PF00038.16 EIW77250.1 - 0.044 13.2 1.3 0.37 10.2 0.0 2.0 1 1 1 2 2 2 0 Intermediate filament protein ADIP PF11559.3 EIW77250.1 - 0.18 11.6 0.8 1.2 9.0 0.0 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 EIW77250.1 - 0.5 9.4 3.0 5.3 6.1 0.4 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein X PF00739.14 EIW77250.1 - 3.7 7.4 5.6 16 5.4 0.1 2.7 2 0 0 2 2 2 0 Trans-activation protein X Tropomyosin_1 PF12718.2 EIW77252.1 - 0.0036 17.1 0.7 0.0036 17.1 0.5 2.1 2 0 0 2 2 2 1 Tropomyosin like IncA PF04156.9 EIW77253.1 - 0.0022 17.6 1.0 0.0022 17.6 0.7 2.1 2 0 0 2 2 2 1 IncA protein Phage_GP20 PF06810.6 EIW77253.1 - 1.2 8.5 6.6 0.65 9.4 0.3 2.7 2 1 1 3 3 3 0 Phage minor structural protein GP20 SKIP_SNW PF02731.10 EIW77253.1 - 4.2 6.8 9.1 0.49 9.8 2.9 1.9 2 1 1 3 3 3 0 SKIP/SNW domain Tropomyosin_1 PF12718.2 EIW77253.1 - 4.4 7.1 11.4 4.1 7.2 1.2 3.0 2 1 1 3 3 3 0 Tropomyosin like IncA PF04156.9 EIW77255.1 - 9.5e-06 25.3 6.8 0.0076 15.8 0.3 3.2 3 0 0 3 3 3 3 IncA protein DUF4246 PF14033.1 EIW77255.1 - 0.018 13.6 0.2 0.027 13.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) DUF342 PF03961.8 EIW77255.1 - 0.15 10.4 1.0 0.37 9.1 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DREV PF05219.7 EIW77258.1 - 0.021 13.7 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase BCMA-Tall_bind PF09257.5 EIW77258.1 - 0.084 12.8 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 BCMA, TALL-1 binding FAD_binding_3 PF01494.14 EIW77261.1 - 1.3e-15 57.3 0.0 2.7e-14 52.9 0.0 2.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIW77261.1 - 0.017 15.1 0.1 0.048 13.6 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GST_N_3 PF13417.1 EIW77264.1 - 9.6e-23 80.2 0.0 1.9e-22 79.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW77264.1 - 5.4e-14 51.9 0.0 1.1e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW77264.1 - 2.4e-06 27.3 0.1 5.8e-05 22.9 0.1 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW77264.1 - 3.4e-05 23.7 0.0 6.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW77264.1 - 0.00093 19.3 0.0 0.0018 18.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EIW77265.1 - 1.2e-13 51.0 0.1 8.9e-13 48.2 0.1 2.1 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW77265.1 - 4.8e-07 29.6 0.3 1.5e-06 28.0 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW77265.1 - 2.1e-06 27.5 0.3 2.6e-05 24.0 0.1 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW77265.1 - 1.5e-05 24.8 0.0 2.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ComFB PF10719.4 EIW77265.1 - 0.06 13.0 0.2 0.14 11.9 0.0 1.6 2 0 0 2 2 2 0 Late competence development protein ComFB CH PF00307.26 EIW77266.1 - 1.7e-64 214.6 0.0 9.8e-18 64.1 0.1 4.8 4 1 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EIW77266.1 - 1.1e-05 25.0 0.0 0.73 9.5 0.0 4.3 4 0 0 4 4 4 2 CAMSAP CH domain EF-hand_7 PF13499.1 EIW77266.1 - 0.037 14.1 0.3 0.16 12.1 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain pair SET PF00856.23 EIW77268.1 - 7.1e-11 42.6 0.0 1.4e-08 35.2 0.0 2.5 2 0 0 2 2 2 2 SET domain zf-MYND PF01753.13 EIW77268.1 - 1.8e-10 40.5 14.9 1.8e-10 40.5 10.3 2.4 2 1 0 2 2 2 1 MYND finger OTCace_N PF02729.16 EIW77268.1 - 0.074 12.7 0.1 5.4 6.6 0.0 2.3 1 1 1 2 2 2 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DnaJ PF00226.26 EIW77269.1 - 7.8e-16 57.5 1.2 1.4e-15 56.8 0.9 1.4 1 0 0 1 1 1 1 DnaJ domain DUF4013 PF13197.1 EIW77270.1 - 0.00035 19.9 1.5 0.00041 19.7 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4013) TGT PF01702.13 EIW77271.1 - 2.4e-20 72.8 0.0 2.7e-16 59.5 0.0 2.9 2 1 0 2 2 2 2 Queuine tRNA-ribosyltransferase Sporozoite_P67 PF05642.6 EIW77272.1 - 3.7 5.2 16.8 0.11 10.3 6.4 1.9 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Peptidase_U9 PF03420.8 EIW77273.1 - 0.17 11.1 5.4 0.088 12.0 0.8 2.2 2 0 0 2 2 2 0 Prohead core protein protease Pkinase PF00069.20 EIW77275.1 - 8.4e-41 139.8 0.0 3.5e-28 98.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW77275.1 - 5.2e-23 81.4 0.0 7.9e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase XRCC4 PF06632.7 EIW77275.1 - 3.5 6.3 5.4 5.2 5.8 2.3 1.9 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF964 PF06133.6 EIW77276.1 - 0.5 10.4 4.0 1.5 8.8 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF964) V-SNARE PF05008.10 EIW77276.1 - 6.8 6.9 6.7 12 6.1 0.1 3.5 4 0 0 4 4 4 0 Vesicle transport v-SNARE protein N-terminus ADH_zinc_N PF00107.21 EIW77282.1 - 4.6e-14 52.0 0.0 1.1e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW77282.1 - 2.3e-13 51.1 0.0 5.4e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW77282.1 - 6.7e-07 29.0 0.5 6e-06 25.9 0.1 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EIW77282.1 - 0.00093 19.2 0.2 0.0014 18.6 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding zf-RVT PF13966.1 EIW77283.1 - 0.003 17.8 0.1 0.0043 17.3 0.1 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase NUDIX PF00293.23 EIW77283.1 - 0.045 13.3 0.0 0.052 13.1 0.0 1.1 1 0 0 1 1 1 0 NUDIX domain WH1 PF00568.18 EIW77290.1 - 0.034 13.8 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 WH1 domain Transp_cyt_pur PF02133.10 EIW77295.1 - 7e-37 127.0 34.7 2.8e-36 125.0 24.0 1.8 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Mob1_phocein PF03637.12 EIW77296.1 - 6.7e-25 87.7 0.3 2.8e-24 85.7 0.1 1.8 2 0 0 2 2 2 1 Mob1/phocein family YjgP_YjgQ PF03739.9 EIW77298.1 - 0.15 10.7 0.0 0.15 10.7 0.0 1.5 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family DUF1345 PF07077.6 EIW77298.1 - 3.9 6.9 7.6 15 5.0 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) IncA PF04156.9 EIW77300.1 - 5.2e-06 26.1 13.7 0.079 12.5 0.1 4.2 4 0 0 4 4 4 3 IncA protein Tnp_P_element PF12017.3 EIW77300.1 - 7.9 5.6 7.7 7.1 5.7 0.2 3.3 3 1 1 4 4 4 0 Transposase protein Acetyltransf_8 PF13523.1 EIW77302.1 - 3.1e-36 124.5 0.3 4.1e-36 124.1 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIW77302.1 - 0.0041 17.2 0.1 0.007 16.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Kinetochor_Ybp2 PF08568.5 EIW77303.1 - 8.9e-10 37.4 0.0 4.9e-09 35.0 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised protein family, YAP/Alf4/glomulin FHA PF00498.21 EIW77305.1 - 6e-05 23.0 0.0 0.003 17.6 0.0 2.3 1 1 0 1 1 1 1 FHA domain DnaJ PF00226.26 EIW77306.1 - 2.9e-19 68.5 0.1 5.3e-19 67.7 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Amidase PF01425.16 EIW77307.1 - 8.5e-84 281.9 0.0 1e-83 281.6 0.0 1.1 1 0 0 1 1 1 1 Amidase Exo_endo_phos PF03372.18 EIW77309.1 - 2.7e-08 34.0 0.0 4e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Acetyltransf_8 PF13523.1 EIW77310.1 - 2.1e-34 118.6 0.4 2.6e-34 118.2 0.3 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Amidase PF01425.16 EIW77312.1 - 2.8e-89 299.9 0.0 3.3e-89 299.7 0.0 1.1 1 0 0 1 1 1 1 Amidase A_deaminase PF00962.17 EIW77313.1 - 1.2e-51 175.6 0.0 1.5e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Glyco_hydro_cc PF11790.3 EIW77313.1 - 0.11 11.8 0.6 0.18 11.2 0.4 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core A_deaminase_N PF08451.6 EIW77313.1 - 0.14 12.2 0.0 0.32 11.0 0.0 1.7 1 1 0 1 1 1 0 Adenosine/AMP deaminase N-terminal Cyto_ox_2 PF02322.10 EIW77314.1 - 0.0047 16.1 0.3 0.0047 16.1 0.2 1.8 1 1 1 2 2 2 1 Cytochrome oxidase subunit II RPA_interact_N PF14766.1 EIW77317.1 - 0.048 13.1 10.0 0.078 12.4 2.1 2.4 2 0 0 2 2 2 0 Replication protein A interacting N-terminal RRM_1 PF00076.17 EIW77320.1 - 3.8e-21 74.4 0.0 3.3e-12 45.8 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW77320.1 - 1.3e-17 63.4 0.0 2.1e-08 34.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW77320.1 - 2e-08 33.9 0.0 8.6e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GCHY-1 PF02649.9 EIW77322.1 - 0.091 11.9 0.3 0.098 11.8 0.2 1.1 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 UNC-93 PF05978.11 EIW77324.1 - 0.078 12.4 0.5 0.12 11.8 0.4 1.3 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 DUF2628 PF10947.3 EIW77325.1 - 0.51 10.1 9.0 4.3 7.1 6.2 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2628) NAD_binding_10 PF13460.1 EIW77326.1 - 2.5e-23 83.0 0.2 2.9e-23 82.8 0.2 1.0 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EIW77326.1 - 6e-09 35.4 0.0 9.9e-09 34.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EIW77326.1 - 0.0001 21.8 0.0 0.00013 21.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EIW77326.1 - 0.00085 18.4 0.0 0.0011 18.0 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EIW77326.1 - 0.013 15.7 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EIW77326.1 - 0.055 13.0 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RNase_PH PF01138.16 EIW77330.1 - 1.2e-16 61.2 0.0 1.9e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EIW77330.1 - 5.2e-06 26.2 0.0 8.8e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF1649 PF07855.7 EIW77331.1 - 8.9e-36 123.0 0.1 1e-35 122.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) DUF3194 PF11419.3 EIW77331.1 - 0.017 15.2 0.0 0.052 13.7 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3194) AAA_16 PF13191.1 EIW77332.1 - 4.8e-05 23.4 0.0 5.4e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EIW77332.1 - 0.00038 20.1 0.0 0.00045 19.9 0.0 1.2 1 0 0 1 1 1 1 NACHT domain APS_kinase PF01583.15 EIW77332.1 - 0.00078 19.1 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.17 EIW77332.1 - 0.002 18.2 0.0 0.0026 17.8 0.0 1.2 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 EIW77332.1 - 0.0075 16.4 0.0 0.0092 16.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIW77332.1 - 0.057 13.7 0.0 0.063 13.5 0.0 1.2 1 0 0 1 1 1 0 ABC transporter PIF1 PF05970.9 EIW77332.1 - 0.094 11.6 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase AAA_5 PF07728.9 EIW77332.1 - 0.1 12.3 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TFIIA_gamma_N PF02268.11 EIW77334.1 - 3.6e-26 90.4 0.1 5.2e-26 89.9 0.1 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain TFIIA_gamma_C PF02751.9 EIW77334.1 - 8.8e-24 83.0 0.4 1.2e-23 82.6 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit NAD_binding_10 PF13460.1 EIW77335.1 - 7.3e-22 78.2 0.0 6.5e-20 71.8 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EIW77335.1 - 1.5e-09 37.4 0.0 4.8e-09 35.8 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 EIW77335.1 - 0.0002 20.9 0.0 0.00096 18.6 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sulfotransfer_3 PF13469.1 EIW77335.1 - 0.03 15.2 0.1 0.048 14.6 0.1 1.4 1 1 0 1 1 1 0 Sulfotransferase family adh_short PF00106.20 EIW77335.1 - 0.044 13.6 0.1 0.099 12.5 0.1 1.5 2 0 0 2 2 2 0 short chain dehydrogenase DapB_N PF01113.15 EIW77335.1 - 0.15 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus WD40 PF00400.27 EIW77336.1 - 3.8e-60 197.7 21.7 1.5e-09 37.4 0.0 11.9 12 0 0 12 12 12 8 WD domain, G-beta repeat eIF2A PF08662.6 EIW77336.1 - 1e-16 61.2 0.0 4.1e-05 23.3 0.0 5.1 3 2 2 5 5 5 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIW77336.1 - 2.2e-10 39.3 0.8 0.017 13.2 0.0 4.7 2 2 1 4 4 4 3 Nucleoporin Nup120/160 PD40 PF07676.7 EIW77336.1 - 2.6e-09 36.5 5.6 5.4 6.8 0.0 8.8 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat Apc4_WD40 PF12894.2 EIW77336.1 - 2.5e-08 33.2 0.0 0.98 8.9 0.0 5.3 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.6 EIW77336.1 - 1.6e-07 30.4 0.6 2.3 6.8 0.0 4.7 2 2 2 5 5 5 3 Nup133 N terminal like Gmad1 PF10647.4 EIW77336.1 - 1.9e-07 30.7 3.5 0.14 11.5 0.2 4.2 1 1 4 5 5 5 3 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 EIW77336.1 - 4.4e-07 28.5 0.0 0.052 11.8 0.0 4.0 3 1 1 4 4 4 2 Cytochrome D1 heme domain PQQ_2 PF13360.1 EIW77336.1 - 3.5e-05 23.3 3.6 0.24 10.8 0.2 3.9 2 2 0 2 2 2 2 PQQ-like domain Me-amine-dh_H PF06433.6 EIW77336.1 - 0.00039 19.1 0.0 0.22 10.0 0.0 3.0 3 0 0 3 3 3 2 Methylamine dehydrogenase heavy chain (MADH) Reg_prop PF07494.6 EIW77336.1 - 0.00051 19.7 0.0 69 3.9 0.0 5.8 6 0 0 6 6 5 0 Two component regulator propeller TruB_C PF09142.6 EIW77336.1 - 0.0015 18.1 0.1 4.9 6.8 0.0 4.7 4 0 0 4 4 4 1 tRNA Pseudouridine synthase II, C terminal DUF2173 PF09941.4 EIW77336.1 - 0.0036 17.2 0.0 53 3.8 0.0 5.1 5 0 0 5 5 5 0 Uncharacterized conserved protein (DUF2173) DUF2963 PF11178.3 EIW77336.1 - 0.015 14.6 0.5 18 4.8 0.0 4.7 3 2 1 4 4 4 0 Protein of unknown function (DUF2963) IKI3 PF04762.7 EIW77336.1 - 0.028 12.2 1.6 2.2 6.0 0.1 3.9 2 2 1 4 4 4 0 IKI3 family Proteasome_A_N PF10584.4 EIW77336.1 - 0.032 13.5 27.8 7.3 6.0 0.0 8.5 10 0 0 10 10 10 0 Proteasome subunit A N-terminal signature DPPIV_N PF00930.16 EIW77336.1 - 0.042 12.4 0.1 68 1.8 0.0 4.9 6 0 0 6 6 6 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region RHS_repeat PF05593.9 EIW77336.1 - 0.21 11.8 4.0 95 3.3 0.1 4.4 4 0 0 4 4 4 0 RHS Repeat GPI-anchored PF10342.4 EIW77338.1 - 3.7e-05 24.1 3.2 6.3e-05 23.3 2.2 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family STAS_2 PF13466.1 EIW77338.1 - 0.11 12.5 0.1 0.19 11.7 0.1 1.2 1 0 0 1 1 1 0 STAS domain TruB_N PF01509.13 EIW77339.1 - 2.1e-43 148.0 0.0 7.7e-43 146.2 0.0 1.8 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) DUF2360 PF10152.4 EIW77339.1 - 0.13 12.5 5.9 0.25 11.6 0.9 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) AUX_IAA PF02309.11 EIW77339.1 - 0.16 11.7 2.3 0.22 11.2 0.1 2.1 2 1 0 2 2 2 0 AUX/IAA family CAP PF00188.21 EIW77340.1 - 2.3e-19 70.1 5.0 2.8e-19 69.8 3.5 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DHDPS PF00701.17 EIW77341.1 - 4.1e-29 101.0 0.0 1.6e-28 99.1 0.0 1.7 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family WD40 PF00400.27 EIW77343.1 - 2.7e-43 144.3 1.1 3.3e-11 42.6 0.0 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 EIW77343.1 - 2.4e-10 40.4 0.0 0.00023 20.9 0.0 3.4 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 EIW77343.1 - 9.8e-07 27.9 2.0 3.3 7.1 0.0 4.7 4 0 0 4 4 4 3 Proteasome subunit A N-terminal signature Apc4_WD40 PF12894.2 EIW77343.1 - 1.6e-06 27.5 0.0 0.57 9.7 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.3 EIW77343.1 - 2.4e-05 22.7 0.1 1.3 7.0 0.0 3.1 2 2 1 3 3 3 3 Nucleoporin Nup120/160 Gmad1 PF10647.4 EIW77343.1 - 0.00015 21.3 0.1 0.026 13.9 0.0 2.1 1 1 1 2 2 2 2 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 EIW77343.1 - 0.00088 18.8 0.5 20 4.9 0.0 4.2 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 EIW77343.1 - 0.001 18.5 0.4 1.5 8.2 0.1 2.6 2 1 1 3 3 3 2 PQQ-like domain TruB_C PF09142.6 EIW77343.1 - 0.0011 18.6 0.2 11 5.8 0.0 3.4 3 0 0 3 3 3 0 tRNA Pseudouridine synthase II, C terminal Nucleoporin_N PF08801.6 EIW77343.1 - 0.0012 17.6 0.1 2.2 6.9 0.0 3.0 1 1 1 3 3 3 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 EIW77343.1 - 0.0014 17.0 0.0 0.31 9.2 0.0 2.5 2 1 0 2 2 2 2 Cytochrome D1 heme domain Reg_prop PF07494.6 EIW77343.1 - 0.0029 17.4 0.0 28 5.1 0.0 3.8 3 0 0 3 3 3 0 Two component regulator propeller DUF2173 PF09941.4 EIW77343.1 - 0.0043 16.9 0.0 19 5.2 0.0 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2173) DUF2963 PF11178.3 EIW77343.1 - 0.0075 15.6 0.4 22 4.5 0.0 4.4 2 2 2 4 4 4 0 Protein of unknown function (DUF2963) RHS_repeat PF05593.9 EIW77343.1 - 0.17 12.1 2.6 43 4.4 0.1 3.5 3 0 0 3 3 3 0 RHS Repeat DUF4097 PF13349.1 EIW77344.1 - 0.076 12.5 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4097) Rad60-SLD_2 PF13881.1 EIW77345.1 - 1.7e-12 47.1 0.0 5.4e-12 45.5 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EIW77345.1 - 0.014 14.7 0.0 0.061 12.7 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin family TRI5 PF06330.6 EIW77346.1 - 1.5e-19 69.9 0.0 1.9e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Pro_isomerase PF00160.16 EIW77348.1 - 1e-42 145.9 0.1 1.1e-42 145.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EIW77349.1 - 2e-32 109.8 18.0 9.8e-11 41.1 0.0 10.1 10 0 0 10 10 10 7 WD domain, G-beta repeat PD40 PF07676.7 EIW77349.1 - 5.2e-06 26.0 4.8 1.7 8.4 0.1 7.4 8 0 0 8 8 8 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 EIW77349.1 - 6.7e-06 25.7 0.6 0.64 9.4 0.0 4.5 2 2 3 5 5 5 3 PQQ-like domain DPPIV_N PF00930.16 EIW77349.1 - 0.0077 14.8 0.1 6.7 5.1 0.0 4.2 3 2 2 5 5 5 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.6 EIW77349.1 - 0.028 14.1 0.0 36 3.9 0.0 4.2 4 1 1 5 5 5 0 Eukaryotic translation initiation factor eIF2A Hira PF07569.6 EIW77349.1 - 0.085 12.0 0.2 30 3.7 0.0 3.1 2 1 1 3 3 3 0 TUP1-like enhancer of split Proteasome_A_N PF10584.4 EIW77349.1 - 0.11 11.8 12.9 13 5.1 0.0 7.1 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 EIW77351.1 - 1.6e-24 84.8 15.2 4.9e-10 38.8 0.0 5.2 5 0 0 5 5 5 5 WD domain, G-beta repeat eIF2A PF08662.6 EIW77351.1 - 2.1e-05 24.3 0.0 2.9 7.5 0.0 3.5 1 1 1 3 3 3 3 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EIW77351.1 - 2.2e-05 24.0 0.2 7.7 6.3 0.0 4.9 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 EIW77351.1 - 0.00036 20.0 0.0 0.00046 19.7 0.0 1.2 1 0 0 1 1 1 1 PQQ-like domain Nup160 PF11715.3 EIW77351.1 - 0.02 13.0 0.1 0.045 11.8 0.0 1.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EIW77351.1 - 0.058 11.6 0.0 4.3 5.5 0.0 2.3 1 1 1 2 2 2 0 Cytochrome D1 heme domain Acetyltransf_3 PF13302.1 EIW77352.1 - 1.8e-08 34.6 0.0 3.9e-08 33.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_L18ae PF01775.12 EIW77354.1 - 9.9e-60 199.8 0.6 1.2e-59 199.5 0.4 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain DUF4098 PF13345.1 EIW77356.1 - 0.026 14.4 0.9 3.6 7.6 0.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4098) Acetyltransf_3 PF13302.1 EIW77357.1 - 1.5e-10 41.4 0.0 1.1e-09 38.5 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW77357.1 - 6.1e-05 22.9 0.0 0.00015 21.6 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family DUF2227 PF09988.4 EIW77357.1 - 0.092 12.3 0.2 0.18 11.3 0.0 1.5 2 0 0 2 2 2 0 Uncharacterized metal-binding protein (DUF2227) Acetyltransf_3 PF13302.1 EIW77358.1 - 6.5e-14 52.2 0.0 9e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW77358.1 - 7.6e-07 29.0 0.0 1.6e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EIW77358.1 - 0.019 14.7 0.1 0.51 10.1 0.0 2.7 2 1 0 2 2 2 0 FR47-like protein FA_hydroxylase PF04116.8 EIW77359.1 - 3.8e-14 53.0 22.3 3.8e-14 53.0 15.5 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily DUF4098 PF13345.1 EIW77360.1 - 6.7e-05 22.7 3.2 0.0062 16.4 0.1 3.6 4 1 0 4 4 4 2 Domain of unknown function (DUF4098) DUF4097 PF13349.1 EIW77360.1 - 0.019 14.5 0.0 0.046 13.2 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4097) WD40 PF00400.27 EIW77362.1 - 1.5e-74 243.4 23.6 4.2e-10 39.1 0.0 12.2 12 0 0 12 12 12 10 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EIW77362.1 - 3.4e-16 58.4 0.0 0.47 9.9 0.0 7.2 7 0 0 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.6 EIW77362.1 - 8.5e-13 48.4 0.0 0.00062 19.5 0.0 5.8 4 1 1 5 5 5 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EIW77362.1 - 1.4e-12 47.1 0.0 0.038 12.7 0.0 5.3 3 1 2 5 5 5 4 Nup133 N terminal like Nup160 PF11715.3 EIW77362.1 - 1.2e-08 33.5 3.1 0.78 7.7 0.0 6.0 4 1 3 7 7 7 3 Nucleoporin Nup120/160 Gmad1 PF10647.4 EIW77362.1 - 1.2e-08 34.6 3.4 0.00033 20.1 0.1 4.4 1 1 4 5 5 5 3 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.1 EIW77362.1 - 7.5e-08 32.1 7.8 0.00079 18.9 1.7 5.4 2 2 2 4 4 4 2 PQQ-like domain Proteasome_A_N PF10584.4 EIW77362.1 - 8.1e-07 28.2 12.7 8.5 5.8 0.0 8.9 9 0 0 9 9 9 0 Proteasome subunit A N-terminal signature PD40 PF07676.7 EIW77362.1 - 3.2e-06 26.6 0.0 16 5.3 0.0 7.3 9 0 0 9 9 8 0 WD40-like Beta Propeller Repeat TruB_C PF09142.6 EIW77362.1 - 5e-06 26.0 0.3 43 3.8 0.0 6.9 7 0 0 7 7 7 0 tRNA Pseudouridine synthase II, C terminal Me-amine-dh_H PF06433.6 EIW77362.1 - 5.3e-06 25.3 0.0 0.71 8.4 0.0 3.6 3 1 1 4 4 4 2 Methylamine dehydrogenase heavy chain (MADH) Cytochrom_D1 PF02239.11 EIW77362.1 - 4.6e-05 21.8 0.0 0.18 10.0 0.0 4.1 4 1 1 5 5 5 2 Cytochrome D1 heme domain Hira PF07569.6 EIW77362.1 - 6.9e-05 22.1 4.6 1.9 7.6 0.1 5.5 4 2 2 6 6 6 1 TUP1-like enhancer of split Coatomer_WDAD PF04053.9 EIW77362.1 - 0.00011 21.1 0.0 0.15 10.7 0.0 3.2 1 1 2 3 3 3 2 Coatomer WD associated region IKI3 PF04762.7 EIW77362.1 - 0.00021 19.3 0.0 1.3 6.7 0.0 4.4 4 1 0 4 4 4 2 IKI3 family DUF2173 PF09941.4 EIW77362.1 - 0.00037 20.3 0.0 34 4.4 0.0 5.5 5 1 0 5 5 5 0 Uncharacterized conserved protein (DUF2173) SGL PF08450.7 EIW77362.1 - 0.00062 19.2 0.3 1.2 8.4 0.0 4.2 2 1 0 4 4 4 1 SMP-30/Gluconolaconase/LRE-like region FtsQ PF03799.10 EIW77362.1 - 0.0012 19.0 0.0 3.4 7.8 0.0 4.4 4 1 1 5 5 5 1 Cell division protein FtsQ SdiA-regulated PF06977.6 EIW77362.1 - 0.016 14.1 0.0 21 3.9 0.0 3.8 3 1 1 4 4 4 0 SdiA-regulated MRJP PF03022.11 EIW77362.1 - 0.017 14.3 0.0 27 3.8 0.0 4.2 3 1 2 5 5 5 0 Major royal jelly protein GspH PF12019.3 EIW77362.1 - 0.02 15.0 7.5 5.3 7.2 0.2 5.0 1 1 2 3 3 3 0 Type II transport protein GspH Lactonase PF10282.4 EIW77362.1 - 0.043 12.8 0.1 30 3.5 0.0 4.3 4 1 0 4 4 4 0 Lactonase, 7-bladed beta-propeller Sen15 PF09631.5 EIW77362.1 - 0.087 13.0 0.3 71 3.7 0.0 4.4 3 2 2 6 6 6 0 Sen15 protein Flp_Fap PF04964.9 EIW77362.1 - 5.5 6.6 5.9 35 4.1 0.0 3.9 4 0 0 4 4 4 0 Flp/Fap pilin component BTB PF00651.26 EIW77363.1 - 6.6e-12 45.4 0.0 1.1e-10 41.4 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain JAB PF01398.16 EIW77364.1 - 1.7e-27 95.3 0.1 2.8e-27 94.7 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EIW77364.1 - 2.3e-06 27.1 0.0 4.4e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Oxidored-like PF09791.4 EIW77365.1 - 1.3e-16 59.7 0.7 2.4e-16 58.9 0.5 1.4 1 0 0 1 1 1 1 Oxidoreductase-like protein, N-terminal COesterase PF00135.23 EIW77366.1 - 9.2e-88 295.2 0.0 1.2e-87 294.8 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW77366.1 - 2.1e-05 24.2 1.5 4.1e-05 23.2 0.5 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW77366.1 - 0.026 14.2 0.1 0.055 13.2 0.1 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIW77366.1 - 0.036 13.2 0.1 0.058 12.5 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF3717 PF12512.3 EIW77366.1 - 0.059 13.0 0.0 0.15 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3717) Metallophos PF00149.23 EIW77367.1 - 9.8e-09 34.8 0.2 1.3e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIW77367.1 - 2.2e-06 27.5 0.0 5.7e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribonucleas_3_3 PF14622.1 EIW77369.1 - 2.2e-13 50.3 0.0 1.2e-06 28.5 0.0 2.1 2 0 0 2 2 2 2 Ribonuclease-III-like DUF2235 PF09994.4 EIW77370.1 - 3.8e-67 226.5 0.0 4.9e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_3 PF07859.8 EIW77370.1 - 0.061 12.8 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW77370.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.5 1 1 0 2 2 2 0 Alpha/beta hydrolase family LAGLIDADG_2 PF03161.8 EIW77371.1 - 0.09 12.6 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 LAGLIDADG DNA endonuclease family DUF1304 PF06993.7 EIW77371.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) WD40 PF00400.27 EIW77374.1 - 1.7e-19 68.9 6.5 3.8e-10 39.2 0.0 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW77374.1 - 5.9e-05 22.6 0.9 1.8 7.9 0.1 3.8 2 2 1 3 3 3 3 PQQ-like domain Nucleoporin_N PF08801.6 EIW77374.1 - 0.0053 15.5 0.0 0.16 10.7 0.0 2.3 2 0 0 2 2 2 1 Nup133 N terminal like eIF2A PF08662.6 EIW77374.1 - 0.0066 16.1 0.0 2.5 7.7 0.0 3.6 3 2 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIW77374.1 - 0.024 12.7 0.1 0.089 10.9 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF1668 PF07893.8 EIW77374.1 - 0.033 13.3 0.0 3.5 6.6 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1668) BTB PF00651.26 EIW77376.1 - 1.6e-11 44.1 0.0 2.5e-10 40.3 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain WD40 PF00400.27 EIW77377.1 - 6.1e-52 171.7 58.4 1.6e-09 37.2 0.0 21.7 22 0 0 22 22 22 12 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW77377.1 - 5.8e-18 65.2 0.8 0.077 12.4 0.0 9.1 5 3 2 8 8 8 4 PQQ-like domain PD40 PF07676.7 EIW77377.1 - 4.1e-16 58.2 15.2 0.052 13.2 0.0 12.7 14 0 0 14 14 14 5 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EIW77377.1 - 2.5e-10 40.3 0.0 8.2 6.0 0.0 9.0 5 2 3 9 9 9 1 Eukaryotic translation initiation factor eIF2A Lactonase PF10282.4 EIW77377.1 - 1.4e-07 30.9 0.0 4.7 6.1 0.0 7.5 6 4 2 8 8 8 2 Lactonase, 7-bladed beta-propeller Cytochrom_D1 PF02239.11 EIW77377.1 - 4e-07 28.6 0.0 2.7 6.2 0.0 6.2 7 0 0 7 7 7 2 Cytochrome D1 heme domain SGL PF08450.7 EIW77377.1 - 8.6e-06 25.2 0.1 0.98 8.7 0.0 6.0 6 1 2 8 8 8 1 SMP-30/Gluconolaconase/LRE-like region Nucleoporin_N PF08801.6 EIW77377.1 - 5.8e-05 22.0 0.1 13 4.3 0.0 5.3 5 0 0 5 5 5 0 Nup133 N terminal like DUF1668 PF07893.8 EIW77377.1 - 0.00016 20.9 0.0 0.71 8.9 0.0 3.3 3 2 0 3 3 3 2 Protein of unknown function (DUF1668) Hira PF07569.6 EIW77377.1 - 0.00088 18.5 0.5 24 4.0 0.0 5.2 6 1 1 7 7 7 0 TUP1-like enhancer of split Nup160 PF11715.3 EIW77377.1 - 0.0023 16.1 0.3 1.9 6.5 0.0 3.1 3 0 0 3 3 3 2 Nucleoporin Nup120/160 DUF1513 PF07433.6 EIW77377.1 - 0.0068 15.3 0.0 17 4.1 0.0 5.1 6 0 0 6 6 6 0 Protein of unknown function (DUF1513) Apc4_WD40 PF12894.2 EIW77377.1 - 0.012 15.1 0.0 15 5.2 0.0 4.8 6 0 0 6 6 6 0 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 EIW77377.1 - 0.038 11.8 0.0 11 3.6 0.0 4.2 5 0 0 5 5 5 0 IKI3 family YbjQ_1 PF01906.12 EIW77379.1 - 0.034 14.5 0.1 0.045 14.1 0.0 1.1 1 0 0 1 1 1 0 Putative heavy-metal-binding WD40 PF00400.27 EIW77380.1 - 4.9e-30 102.3 25.9 4.3e-09 35.8 0.0 11.7 12 0 0 12 12 12 7 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW77380.1 - 3.2e-11 43.1 0.0 0.0033 16.9 0.0 4.7 3 1 1 4 4 4 2 PQQ-like domain PD40 PF07676.7 EIW77380.1 - 1.4e-08 34.1 8.6 0.23 11.1 0.1 8.4 9 0 0 9 9 9 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 EIW77380.1 - 2.7e-06 25.9 0.0 0.29 9.3 0.0 3.8 3 1 1 4 4 4 4 Cytochrome D1 heme domain eIF2A PF08662.6 EIW77380.1 - 8.6e-06 25.5 0.0 0.26 10.9 0.0 4.3 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A SGL PF08450.7 EIW77380.1 - 0.00026 20.4 0.0 0.096 12.0 0.0 3.7 3 1 1 4 4 4 1 SMP-30/Gluconolaconase/LRE-like region DUF1513 PF07433.6 EIW77380.1 - 0.027 13.3 0.0 7.3 5.3 0.0 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1513) Hira PF07569.6 EIW77380.1 - 0.19 10.9 0.1 16 4.6 0.0 3.1 2 1 1 3 3 3 0 TUP1-like enhancer of split Proteasome_A_N PF10584.4 EIW77380.1 - 0.84 9.0 18.5 9.7 5.6 0.0 6.5 8 0 0 8 8 8 0 Proteasome subunit A N-terminal signature Hydrophobin PF01185.13 EIW77381.1 - 2e-20 73.0 9.6 2.4e-20 72.7 6.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 EIW77382.1 - 8.5e-19 67.7 9.2 1e-18 67.5 6.4 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 EIW77383.1 - 5.1e-17 62.1 11.3 6.2e-17 61.8 7.8 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Citrate_synt PF00285.16 EIW77384.1 - 1.2e-17 63.6 0.1 1.1e-15 57.2 0.0 2.7 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 EIW77384.1 - 2.1e-15 56.6 0.0 4e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 EIW77384.1 - 8.5e-13 48.6 0.0 1.9e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain ATP-grasp_2 PF08442.5 EIW77384.1 - 2.9e-06 26.8 0.0 5.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Succ_CoA_lig PF13607.1 EIW77384.1 - 3.9e-05 23.2 0.0 0.00017 21.2 0.0 2.0 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain zf-RVT PF13966.1 EIW77385.1 - 0.0016 18.6 0.0 0.0021 18.3 0.0 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RNase_H PF00075.19 EIW77386.1 - 1.3e-07 32.0 0.0 1.6e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 RNase H zf-CCHC_5 PF14787.1 EIW77387.1 - 0.044 13.2 0.9 0.044 13.2 0.6 2.5 1 1 1 2 2 2 0 GAG-polyprotein viral zinc-finger ArfGap PF01412.13 EIW77387.1 - 3.1 7.6 8.7 1.3 8.8 1.8 2.2 1 1 1 2 2 2 0 Putative GTPase activating protein for Arf Peptidase_S64 PF08192.6 EIW77388.1 - 3.8 5.7 24.0 5.1 5.3 16.7 1.3 1 0 0 1 1 1 0 Peptidase family S64 ICMT PF04140.9 EIW77389.1 - 6.7e-08 32.6 0.0 1.1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIW77389.1 - 2.5e-06 27.5 0.1 4.1e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EIW77389.1 - 0.037 12.5 0.8 0.13 10.7 0.6 1.8 1 1 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family GST_N PF02798.15 EIW77390.1 - 2.1e-16 59.8 0.0 4.4e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW77390.1 - 1.7e-15 56.7 0.0 2.6e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIW77390.1 - 1.8e-14 53.7 0.0 3.2e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW77390.1 - 2e-09 37.2 0.1 4e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW77390.1 - 4.5e-08 32.9 0.0 7.8e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIW77390.1 - 7e-05 23.2 0.0 8.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EIW77390.1 - 0.097 13.0 0.0 0.29 11.5 0.0 1.7 2 0 0 2 2 2 0 MetRS-N binding domain PEMT PF04191.8 EIW77391.1 - 8.8e-08 32.2 0.3 1.4e-07 31.5 0.2 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.9 EIW77391.1 - 1.4e-07 31.5 1.0 2.3e-07 30.9 0.7 1.3 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF4050 PF13259.1 EIW77392.1 - 0.42 10.5 6.7 0.57 10.1 4.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) GST_N PF02798.15 EIW77393.1 - 7.1e-18 64.5 0.0 1.3e-17 63.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EIW77393.1 - 1.5e-15 57.1 0.0 2.6e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW77393.1 - 5.2e-13 48.7 0.0 7.9e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW77393.1 - 1.8e-10 40.6 0.0 3.4e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW77393.1 - 2e-07 30.7 0.1 3.7e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW77393.1 - 0.00058 20.2 0.0 0.00077 19.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EIW77393.1 - 0.085 13.2 0.0 0.21 11.9 0.0 1.6 2 0 0 2 2 2 0 MetRS-N binding domain GST_N PF02798.15 EIW77394.1 - 4.8e-17 61.8 0.0 7.7e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EIW77394.1 - 2.1e-13 50.3 0.0 3.3e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW77394.1 - 1.7e-08 34.3 0.0 2.9e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MetRS-N PF09635.5 EIW77394.1 - 0.067 13.5 0.0 0.18 12.1 0.0 1.6 2 0 0 2 2 2 0 MetRS-N binding domain GST_N PF02798.15 EIW77399.1 - 2.2e-15 56.5 0.0 5.2e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EIW77399.1 - 1.5e-13 50.7 0.0 2.7e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW77399.1 - 5.4e-13 48.7 0.0 8.1e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIW77399.1 - 3.2e-08 33.3 0.0 5.7e-08 32.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW77399.1 - 3e-07 30.3 0.0 5.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIW77399.1 - 0.026 15.0 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Hydrophobin PF01185.13 EIW77400.1 - 1.1e-21 77.1 9.5 1.3e-21 76.8 6.6 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF2264 PF10022.4 EIW77401.1 - 4.4e-133 443.3 0.4 5.4e-133 443.1 0.3 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Plant_vir_prot PF01307.12 EIW77401.1 - 0.06 13.0 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Plant viral movement protein DUF1772 PF08592.6 EIW77402.1 - 0.046 13.4 0.7 0.051 13.3 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1772) Pyr_redox_3 PF13738.1 EIW77403.1 - 3.4e-19 69.7 0.0 2.5e-18 66.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIW77403.1 - 4.9e-16 58.0 0.0 3.2e-14 52.0 0.0 2.6 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EIW77403.1 - 5.9e-12 45.1 0.1 5.8e-11 41.8 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EIW77403.1 - 9.1e-11 42.0 0.0 1.6e-09 37.9 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIW77403.1 - 3.4e-06 26.9 0.1 0.32 10.7 0.0 4.0 4 0 0 4 4 4 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EIW77403.1 - 1.3e-05 25.1 0.0 9.9e-05 22.2 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIW77403.1 - 5.5e-05 22.2 0.2 0.43 9.4 0.1 3.6 4 0 0 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.12 EIW77403.1 - 0.0001 21.4 0.2 0.00081 18.5 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EIW77403.1 - 0.00039 19.5 0.1 0.00072 18.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EIW77403.1 - 0.00069 18.6 0.2 0.45 9.3 0.0 3.1 3 0 0 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.9 EIW77403.1 - 0.0028 16.2 0.2 0.44 8.9 0.0 3.0 4 0 0 4 4 4 1 HI0933-like protein Mqo PF06039.10 EIW77403.1 - 0.0092 14.2 0.0 0.016 13.4 0.0 1.3 1 0 0 1 1 1 1 Malate:quinone oxidoreductase (Mqo) Shikimate_DH PF01488.15 EIW77403.1 - 0.011 15.8 0.0 0.65 10.1 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EIW77403.1 - 0.012 14.5 0.1 1.6 7.5 0.0 3.3 4 0 0 4 4 4 0 FAD binding domain NAD_binding_7 PF13241.1 EIW77403.1 - 0.015 15.5 0.0 3.1 8.1 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EIW77403.1 - 0.19 11.3 0.0 7.1 6.2 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EIW77403.1 - 0.38 9.5 0.9 58 2.3 0.0 3.3 4 0 0 4 4 4 0 Glucose inhibited division protein A Herpes_UL51 PF04540.8 EIW77404.1 - 0.25 10.9 0.9 0.37 10.3 0.6 1.2 1 0 0 1 1 1 0 Herpesvirus UL51 protein Pyr_redox_3 PF13738.1 EIW77405.1 - 4.2e-22 79.2 0.0 1.8e-20 73.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIW77405.1 - 3.1e-14 52.0 0.0 4.4e-13 48.2 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EIW77405.1 - 8.9e-12 44.5 0.2 5e-09 35.5 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EIW77405.1 - 1.6e-09 37.9 0.0 0.00038 20.3 0.0 3.2 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW77405.1 - 1.6e-08 34.3 1.0 4e-06 26.7 0.0 3.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIW77405.1 - 2.1e-06 26.9 0.7 0.00086 18.4 0.0 2.6 3 0 0 3 3 3 2 Thi4 family DAO PF01266.19 EIW77405.1 - 5.6e-06 25.5 0.1 0.0013 17.7 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EIW77405.1 - 1.3e-05 24.3 0.9 0.0031 16.6 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 EIW77405.1 - 1.7e-05 24.6 0.2 0.1 12.3 0.1 3.4 2 1 1 3 3 3 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EIW77405.1 - 0.00019 20.3 2.2 0.0004 19.3 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EIW77405.1 - 0.00022 19.8 0.1 0.051 12.0 0.1 2.9 4 0 0 4 4 4 1 HI0933-like protein Pyr_redox PF00070.22 EIW77405.1 - 0.00023 21.5 0.8 0.032 14.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EIW77405.1 - 0.00024 21.3 0.0 1.1 9.5 0.0 2.3 2 0 0 2 2 2 2 Putative NAD(P)-binding B12-binding PF02310.14 EIW77405.1 - 0.0069 16.2 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 B12 binding domain Shikimate_DH PF01488.15 EIW77405.1 - 0.0091 16.0 0.2 6 6.9 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EIW77405.1 - 0.032 14.0 0.4 0.32 10.8 0.0 2.2 2 0 0 2 2 2 0 ThiF family Glycos_transf_1 PF00534.15 EIW77405.1 - 0.042 13.2 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 3HCDH_N PF02737.13 EIW77405.1 - 0.066 12.8 0.4 8.7 5.9 0.1 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EIW77405.1 - 0.069 12.0 0.5 1.1 8.0 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein GIDA PF01134.17 EIW77405.1 - 0.085 11.6 2.4 8.9 5.0 0.3 2.9 3 0 0 3 3 3 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 EIW77405.1 - 0.086 12.5 0.4 8.1 6.1 0.1 2.9 3 0 0 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FAD_oxidored PF12831.2 EIW77405.1 - 0.098 11.7 0.1 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_10 PF13460.1 EIW77405.1 - 0.14 12.1 0.5 2.8 7.9 0.0 2.4 2 0 0 2 2 2 0 NADH(P)-binding ELFV_dehydrog PF00208.16 EIW77405.1 - 0.17 11.3 0.1 12 5.3 0.0 2.2 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ApbA PF02558.11 EIW77405.1 - 0.4 10.1 1.4 4.2 6.7 0.1 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA MFS_1 PF07690.11 EIW77407.1 - 2.4e-22 79.1 20.0 3.4e-22 78.6 13.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MxiH PF09392.5 EIW77409.1 - 1.8 9.1 6.6 41 4.8 0.0 2.5 2 0 0 2 2 2 0 Type III secretion needle MxiH like Tcp11 PF05794.8 EIW77410.1 - 0.0017 17.1 0.2 0.0019 16.9 0.1 1.1 1 0 0 1 1 1 1 T-complex protein 11 DUF4164 PF13747.1 EIW77410.1 - 0.017 15.2 0.2 0.13 12.4 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) DUF1073 PF06381.6 EIW77410.1 - 0.13 10.7 0.1 1.9 6.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1073) Ammonium_transp PF00909.16 EIW77411.1 - 4.8e-119 397.4 24.0 5.5e-119 397.2 16.7 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Abhydrolase_9_N PF15420.1 EIW77414.1 - 1 9.0 7.7 0.041 13.6 0.8 1.8 2 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus HET PF06985.6 EIW77415.1 - 1e-22 80.7 0.3 7e-18 65.1 0.0 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Cys_Met_Meta_PP PF01053.15 EIW77416.1 - 2e-126 421.4 0.0 4.8e-96 321.3 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EIW77416.1 - 0.029 13.3 0.0 0.041 12.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II LRR_8 PF13855.1 EIW77417.1 - 0.02 14.6 2.9 5.7 6.7 0.0 4.6 5 1 0 5 5 5 0 Leucine rich repeat DAO PF01266.19 EIW77419.1 - 0.025 13.4 0.0 0.027 13.3 0.0 1.1 1 0 0 1 1 1 0 FAD dependent oxidoreductase F-box PF00646.28 EIW77420.1 - 3.3e-08 32.9 0.6 6.7e-08 31.9 0.4 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW77420.1 - 0.0017 18.0 0.5 0.0029 17.3 0.4 1.4 1 0 0 1 1 1 1 F-box-like Pyr_redox_3 PF13738.1 EIW77421.1 - 3.3e-20 73.0 0.0 5.5e-19 69.0 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIW77421.1 - 5.4e-13 47.9 0.0 9.1e-13 47.2 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EIW77421.1 - 3.3e-11 42.7 0.6 1.5e-10 40.5 0.0 2.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EIW77421.1 - 7.2e-08 32.3 0.1 3e-07 30.3 0.0 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIW77421.1 - 4.3e-07 30.0 0.0 3.4e-05 23.8 0.0 2.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIW77421.1 - 1.1e-06 28.5 0.6 0.012 15.3 0.2 3.4 2 1 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.9 EIW77421.1 - 3.3e-05 22.5 0.7 0.13 10.7 0.3 2.5 3 0 0 3 3 3 2 HI0933-like protein DAO PF01266.19 EIW77421.1 - 5.5e-05 22.2 2.5 0.027 13.3 0.4 3.4 3 1 0 3 3 3 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EIW77421.1 - 0.00014 21.0 0.3 0.21 10.6 0.0 3.3 3 1 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 EIW77421.1 - 0.0019 17.2 3.5 0.018 14.1 0.3 2.6 2 1 1 3 3 3 1 FAD binding domain FAD_binding_2 PF00890.19 EIW77421.1 - 0.0024 16.7 3.4 0.019 13.8 0.6 2.5 3 0 0 3 3 3 1 FAD binding domain NAD_binding_10 PF13460.1 EIW77421.1 - 0.0028 17.6 0.3 0.6 10.0 0.0 2.7 2 0 0 2 2 2 1 NADH(P)-binding Thi4 PF01946.12 EIW77421.1 - 0.0069 15.5 0.9 0.029 13.4 0.1 2.1 2 0 0 2 2 2 1 Thi4 family Cas_APE2256 PF09651.5 EIW77421.1 - 0.0085 15.7 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_APE2256) Shikimate_DH PF01488.15 EIW77421.1 - 0.013 15.6 0.3 0.21 11.7 0.1 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EIW77421.1 - 0.023 14.3 1.1 4.4 6.9 0.3 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EIW77421.1 - 0.037 13.4 0.5 0.14 11.5 0.1 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 EIW77421.1 - 0.066 12.1 0.3 3.1 6.6 0.1 2.8 2 1 0 2 2 2 0 Lycopene cyclase protein Mqo PF06039.10 EIW77421.1 - 0.16 10.0 0.0 0.28 9.3 0.0 1.3 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) ThiF PF00899.16 EIW77421.1 - 0.18 11.6 0.2 0.51 10.1 0.1 1.7 2 0 0 2 2 2 0 ThiF family Pyr_redox PF00070.22 EIW77421.1 - 0.28 11.6 1.0 41 4.6 0.0 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIW77421.1 - 0.34 9.7 2.3 11 4.6 0.4 3.0 3 0 0 3 3 3 0 Glucose inhibited division protein A Trypsin_2 PF13365.1 EIW77422.1 - 2.7e-05 24.1 0.0 0.0001 22.2 0.0 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S32 PF05579.8 EIW77422.1 - 0.0037 16.2 0.1 0.0085 15.0 0.0 1.5 2 0 0 2 2 2 1 Equine arteritis virus serine endopeptidase S32 Peptidase_S3 PF00944.14 EIW77422.1 - 0.029 13.7 0.1 0.058 12.8 0.1 1.4 1 0 0 1 1 1 0 Alphavirus core protein HET PF06985.6 EIW77423.1 - 1.2e-18 67.6 6.3 7.3e-16 58.5 0.5 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) gpUL132 PF11359.3 EIW77424.1 - 0.082 12.2 1.3 0.28 10.4 0.9 1.9 1 1 0 1 1 1 0 Glycoprotein UL132 eIF3g PF12353.3 EIW77425.1 - 6.5e-42 142.4 1.3 9.9e-42 141.8 0.9 1.3 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EIW77425.1 - 3.1e-17 61.9 0.0 5.6e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW77425.1 - 7.3e-16 57.9 0.0 1.3e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW77425.1 - 2.1e-08 33.8 0.0 4.2e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIW77425.1 - 0.011 15.5 0.5 0.079 12.8 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif Hemolysin_N PF12563.3 EIW77425.1 - 0.26 10.7 0.9 9.5 5.6 0.0 2.1 2 0 0 2 2 2 0 Hemolytic toxin N terminal F-box-like PF12937.2 EIW77427.1 - 0.0084 15.8 0.0 0.042 13.5 0.0 2.2 1 1 0 1 1 1 1 F-box-like AdoMet_MTase PF07757.8 EIW77428.1 - 4.3e-32 110.5 0.0 6.6e-16 58.4 0.0 2.2 2 0 0 2 2 2 2 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 EIW77428.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.1 EIW77428.1 - 0.035 13.7 0.0 0.077 12.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EIW77428.1 - 0.11 13.0 0.1 0.21 12.1 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EIW77428.1 - 0.16 11.5 0.1 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EIW77428.1 - 0.24 10.7 0.0 0.38 10.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain PCI PF01399.22 EIW77429.1 - 6.2e-06 26.4 0.0 1.5e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 PCI domain FMO-like PF00743.14 EIW77431.1 - 4.6e-28 97.7 0.0 4.8e-15 54.7 0.0 3.6 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EIW77431.1 - 1.4e-12 48.1 0.0 1.8e-07 31.4 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW77431.1 - 5.8e-08 32.6 0.0 3.4e-07 30.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIW77431.1 - 1.2e-07 31.8 0.0 0.0076 16.1 0.0 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW77431.1 - 2.8e-06 26.5 0.0 2e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 EIW77431.1 - 5.1e-06 25.6 0.0 0.00038 19.4 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EIW77431.1 - 8.9e-05 22.3 0.0 0.00049 19.8 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EIW77431.1 - 0.0049 15.9 0.1 0.01 14.9 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EIW77431.1 - 0.0072 15.2 0.0 0.018 13.9 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EIW77431.1 - 0.008 14.6 0.0 0.017 13.6 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.19 EIW77431.1 - 0.021 13.8 0.0 0.12 11.4 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EIW77431.1 - 0.082 13.3 0.0 5.3 7.5 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RES PF08808.6 EIW77432.1 - 0.13 12.3 0.1 0.56 10.2 0.0 2.0 3 0 0 3 3 3 0 RES domain FMO-like PF00743.14 EIW77433.1 - 1.3e-25 89.5 0.0 1e-13 50.3 0.0 3.5 2 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EIW77433.1 - 3.6e-10 40.2 0.0 6.5e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW77433.1 - 1.4e-07 31.4 0.0 6.4e-07 29.3 0.0 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIW77433.1 - 6.8e-06 26.1 0.0 0.032 14.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW77433.1 - 0.00017 20.7 0.0 0.00059 18.9 0.0 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 EIW77433.1 - 0.0004 20.1 0.0 0.0013 18.5 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EIW77433.1 - 0.00057 18.9 0.0 0.017 14.0 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EIW77433.1 - 0.0011 17.9 0.0 0.0038 16.1 0.0 1.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase FMN_red PF03358.10 EIW77433.1 - 0.0023 17.4 0.0 0.0043 16.5 0.0 1.4 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Amino_oxidase PF01593.19 EIW77433.1 - 0.0024 17.0 0.0 0.023 13.7 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 EIW77433.1 - 0.0058 15.7 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_7 PF13241.1 EIW77433.1 - 0.12 12.6 0.0 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding HI0933_like PF03486.9 EIW77433.1 - 0.17 10.3 0.0 0.3 9.5 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein PGI PF00342.14 EIW77434.1 - 8.7e-216 717.0 0.1 1e-215 716.8 0.1 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF600 PF04634.7 EIW77436.1 - 0.093 12.7 0.1 0.39 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF600 p450 PF00067.17 EIW77437.1 - 1.6e-57 195.0 0.0 3.4e-57 193.9 0.0 1.5 2 0 0 2 2 2 1 Cytochrome P450 DUF2235 PF09994.4 EIW77438.1 - 3.4e-56 190.6 0.0 3.8e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Esterase PF00756.15 EIW77438.1 - 0.0044 16.4 0.0 0.033 13.6 0.0 2.0 2 0 0 2 2 2 1 Putative esterase Abhydrolase_5 PF12695.2 EIW77438.1 - 0.022 14.4 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_M1 PF01433.15 EIW77439.1 - 1.8e-114 382.8 0.0 1.7e-70 238.1 0.0 2.4 1 1 1 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 EIW77439.1 - 3.9e-52 177.5 0.1 5.6e-52 177.0 0.1 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EIW77439.1 - 6.3e-16 58.5 0.0 1.3e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily EHN PF06441.7 EIW77440.1 - 8.1e-29 99.8 0.1 1.4e-28 99.0 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EIW77440.1 - 4e-09 36.6 9.5 5.6e-09 36.2 4.0 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW77440.1 - 2.4e-07 30.5 0.5 6.3e-06 25.9 0.2 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF4646 PF15496.1 EIW77441.1 - 2.3e-24 85.8 0.0 4.3e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) APH PF01636.18 EIW77442.1 - 1.5e-08 34.6 0.0 1.9e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EIW77442.1 - 0.00013 21.2 0.0 0.00025 20.2 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain EcKinase PF02958.15 EIW77442.1 - 0.03 13.4 0.0 0.036 13.1 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 EIW77442.1 - 0.066 12.7 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase DUF1275 PF06912.6 EIW77444.1 - 2.8e-23 82.2 16.3 3.6e-23 81.8 11.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MFS_1 PF07690.11 EIW77444.1 - 6.8e-05 21.7 19.1 0.00015 20.5 5.7 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily HET PF06985.6 EIW77445.1 - 2.8e-19 69.6 4.7 6.9e-16 58.6 0.7 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Hydrophobin PF01185.13 EIW77446.1 - 2.7e-21 75.7 10.6 3.3e-21 75.5 7.3 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF4418 PF14387.1 EIW77446.1 - 0.049 13.3 0.2 0.049 13.3 0.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4418) Defensin_beta PF00711.14 EIW77446.1 - 0.17 11.8 0.8 0.17 11.8 0.6 2.3 2 0 0 2 2 2 0 Beta defensin Toxin_12 PF07740.7 EIW77446.1 - 6.2 7.3 13.3 4.8 7.7 0.6 2.9 3 1 0 3 3 3 0 Ion channel inhibitory toxin Defensin_2 PF01097.13 EIW77446.1 - 6.7 6.5 11.0 0.21 11.3 2.0 2.2 2 0 0 2 2 2 0 Arthropod defensin HpcH_HpaI PF03328.9 EIW77447.1 - 1.6e-33 115.4 0.0 2e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF4514 PF14986.1 EIW77447.1 - 0.033 14.0 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4514) HET PF06985.6 EIW77448.1 - 7.3e-18 65.0 1.8 1.5e-14 54.3 0.0 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF1275 PF06912.6 EIW77452.1 - 2e-22 79.4 21.4 2.8e-22 78.9 14.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) DUF1275 PF06912.6 EIW77453.1 - 1.2e-20 73.6 19.0 1.5e-20 73.3 13.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MFS_1 PF07690.11 EIW77453.1 - 2.6e-05 23.1 7.8 2.6e-05 23.1 5.4 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Vac14_Fig4_bd PF11916.3 EIW77453.1 - 0.097 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Vacuolar protein 14 C-terminal Fig4p binding HET PF06985.6 EIW77454.1 - 3.6e-18 66.0 5.2 1.3e-15 57.8 0.3 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) TC1 PF15063.1 EIW77455.1 - 0.35 10.4 2.5 0.51 9.9 0.1 2.2 2 0 0 2 2 2 0 Thyroid cancer protein 1 SOCS_box PF07525.11 EIW77457.1 - 0.031 14.1 0.6 0.79 9.6 0.4 2.6 2 0 0 2 2 2 0 SOCS box HET PF06985.6 EIW77458.1 - 3.5e-21 75.8 3.2 2.6e-17 63.2 0.2 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_trans_2_3 PF13632.1 EIW77458.1 - 0.045 13.4 0.3 0.076 12.7 0.0 1.5 2 0 0 2 2 2 0 Glycosyl transferase family group 2 FHA PF00498.21 EIW77459.1 - 1.4e-14 53.9 0.0 1.8e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 FHA domain DUF4218 PF13960.1 EIW77460.1 - 0.0069 15.8 0.1 0.016 14.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) CHAT PF12770.2 EIW77462.1 - 1.4e-29 103.1 0.1 3.6e-29 101.7 0.1 1.7 1 0 0 1 1 1 1 CHAT domain TPR_2 PF07719.12 EIW77462.1 - 0.028 14.3 0.5 0.028 14.3 0.3 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat HET PF06985.6 EIW77463.1 - 3.5e-18 66.1 7.3 1.8e-15 57.3 0.1 2.5 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Glyco_trans_2_3 PF13632.1 EIW77463.1 - 0.15 11.7 0.2 0.15 11.7 0.1 1.5 2 0 0 2 2 2 0 Glycosyl transferase family group 2 FHA PF00498.21 EIW77464.1 - 5.9e-16 58.3 0.0 1.4e-15 57.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain TMF_DNA_bd PF12329.3 EIW77464.1 - 0.00054 19.7 10.4 0.0044 16.7 3.1 3.2 2 1 0 2 2 2 1 TATA element modulatory factor 1 DNA binding Reo_sigmaC PF04582.7 EIW77464.1 - 0.045 12.9 4.7 1.3 8.1 0.5 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF972 PF06156.8 EIW77464.1 - 0.17 12.2 11.3 2.2 8.6 1.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) ALIX_LYPXL_bnd PF13949.1 EIW77464.1 - 0.24 10.3 16.9 0.018 13.9 3.9 2.4 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV NPV_P10 PF05531.7 EIW77464.1 - 0.47 10.7 2.7 98 3.3 0.7 3.6 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 EIW77464.1 - 0.81 9.5 4.8 3.2 7.5 0.4 2.8 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EIW77464.1 - 2.9 7.7 9.1 0.16 11.7 1.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) RRN3 PF05327.6 EIW77464.1 - 3.1 5.8 7.1 4.3 5.3 4.5 1.5 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 FAD-SLDH PF12318.3 EIW77464.1 - 6.4 6.4 5.7 5 6.7 0.0 2.8 3 0 0 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase Ferritin_2 PF13668.1 EIW77465.1 - 0.0014 18.6 0.0 0.0025 17.7 0.0 1.4 1 1 0 1 1 1 1 Ferritin-like domain Ferritin_2 PF13668.1 EIW77466.1 - 8.9e-42 142.2 3.9 1.3e-41 141.7 2.7 1.2 1 0 0 1 1 1 1 Ferritin-like domain Gln-synt_C PF00120.19 EIW77468.1 - 2.7e-53 180.7 0.0 3.6e-53 180.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Glyco_hydro_43 PF04616.9 EIW77469.1 - 1.4e-31 109.7 0.0 1.7e-31 109.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 BNR PF02012.15 EIW77469.1 - 0.65 10.0 2.6 1.2 9.2 0.2 2.8 2 0 0 2 2 2 0 BNR/Asp-box repeat Glyco_hydro_43 PF04616.9 EIW77470.1 - 1.4e-31 109.6 0.0 1.6e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 BNR_2 PF13088.1 EIW77470.1 - 0.022 14.0 0.2 0.061 12.6 0.1 1.8 1 1 0 2 2 2 0 BNR repeat-like domain Mo-co_dimer PF03404.11 EIW77470.1 - 0.04 13.5 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain BNR PF02012.15 EIW77470.1 - 0.064 13.1 0.3 1.1 9.3 0.0 2.9 2 0 0 2 2 2 0 BNR/Asp-box repeat NIF PF03031.13 EIW77471.1 - 2.5e-08 33.7 0.0 4.5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF605 PF04652.11 EIW77471.1 - 4.4 6.5 16.2 0.089 12.1 6.7 1.4 2 0 0 2 2 2 0 Vta1 like DUF3602 PF12223.3 EIW77472.1 - 2.8e-27 94.9 35.3 2.8e-06 27.6 0.5 5.9 1 1 5 6 6 6 6 Protein of unknown function (DUF3602) PAPA-1 PF04795.7 EIW77473.1 - 3.5e-14 53.2 7.8 3.5e-14 53.2 5.4 3.7 4 1 1 5 5 5 1 PAPA-1-like conserved region COPI_C PF06957.6 EIW77473.1 - 9.8 4.5 11.8 20 3.5 8.2 1.5 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Glyco_hydro_10 PF00331.15 EIW77476.1 - 4.9e-92 308.3 0.0 6.2e-92 308.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 EIW77476.1 - 7.8e-11 41.4 16.5 2.2e-10 39.9 11.5 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_61 PF03443.9 EIW77477.1 - 1.2e-62 211.5 2.2 1.6e-62 211.1 1.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EIW77477.1 - 1.2e-10 40.8 14.9 1.2e-10 40.8 10.3 2.6 2 0 0 2 2 2 1 Fungal cellulose binding domain Flavodoxin_1 PF00258.20 EIW77478.1 - 1e-06 28.7 0.0 3.1e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 EIW77478.1 - 3e-06 26.7 0.0 5.1e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EIW77478.1 - 0.00081 18.9 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold FMN_red PF03358.10 EIW77479.1 - 8.7e-08 31.8 0.0 1.2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_1 PF00258.20 EIW77479.1 - 0.0025 17.8 0.0 0.0074 16.2 0.0 1.8 1 1 0 1 1 1 1 Flavodoxin ComC PF03047.9 EIW77479.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 COMC family Glyco_hydro_28 PF00295.12 EIW77480.1 - 1.7e-37 129.0 0.0 3.9e-37 127.9 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EIW77480.1 - 0.035 13.8 11.4 0.014 15.1 5.3 2.4 2 1 0 2 2 2 0 Right handed beta helix region GFA PF04828.9 EIW77481.1 - 1.9e-20 72.5 2.2 1.6e-19 69.6 1.5 2.0 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 EIW77481.1 - 0.0024 17.5 0.1 0.0024 17.5 0.0 2.7 3 0 0 3 3 3 1 Nudix N-terminal zf-B_box PF00643.19 EIW77481.1 - 0.16 11.9 0.1 0.16 11.9 0.0 2.8 4 0 0 4 4 4 0 B-box zinc finger NAGLU PF05089.7 EIW77482.1 - 5.2e-122 406.7 1.9 7.3e-122 406.2 1.3 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 EIW77482.1 - 1e-63 215.2 1.0 1.5e-63 214.6 0.7 1.3 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 EIW77482.1 - 3.5e-17 61.8 0.0 8.9e-17 60.5 0.0 1.7 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain NTR2 PF15458.1 EIW77483.1 - 0.051 12.8 0.9 0.084 12.1 0.6 1.3 1 0 0 1 1 1 0 Nineteen complex-related protein 2 DZR PF12773.2 EIW77483.1 - 2.9 7.7 5.6 4.5 7.1 0.5 2.6 3 0 0 3 3 3 0 Double zinc ribbon MAD PF05557.8 EIW77484.1 - 1.4e-33 115.9 52.3 7.1e-33 113.6 36.2 2.0 1 1 0 1 1 1 1 Mitotic checkpoint protein TIM-br_sig_trns PF09370.5 EIW77484.1 - 0.069 12.2 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 TIM-barrel signal transduction protein BLOC1_2 PF10046.4 EIW77484.1 - 0.15 12.1 0.1 0.15 12.1 0.1 5.6 6 1 0 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF262 PF03235.9 EIW77485.1 - 7.1e-15 55.5 2.9 3e-14 53.5 0.8 2.4 2 1 1 3 3 3 1 Protein of unknown function DUF262 DUF4464 PF14713.1 EIW77485.1 - 0.065 12.6 0.5 0.23 10.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4464) Nitr_red_bet_C PF14711.1 EIW77485.1 - 0.11 11.9 0.3 0.28 10.7 0.2 1.6 1 0 0 1 1 1 0 Respiratory nitrate reductase beta C-terminal OPT PF03169.10 EIW77486.1 - 3.9e-196 653.2 64.4 4.5e-196 653.0 44.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2370 PF10176.4 EIW77486.1 - 0.054 12.8 0.8 0.1 11.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) DUF4083 PF13314.1 EIW77486.1 - 0.12 12.2 0.1 0.12 12.2 0.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) HET PF06985.6 EIW77487.1 - 5.3e-20 71.9 3.1 5.5e-17 62.2 0.1 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.6 EIW77488.1 - 3.1e-19 69.5 3.0 5e-17 62.3 0.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_trans_2_3 PF13632.1 EIW77488.1 - 0.015 15.0 0.7 0.027 14.1 0.5 1.3 1 1 0 1 1 1 0 Glycosyl transferase family group 2 OPT PF03169.10 EIW77489.1 - 6.7e-200 665.6 61.9 7.6e-200 665.4 42.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2383 PF09537.5 EIW77490.1 - 0.044 14.0 0.7 0.26 11.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) IncA PF04156.9 EIW77490.1 - 4.8 6.7 6.8 74 2.8 3.3 2.6 2 1 0 2 2 2 0 IncA protein DUF1242 PF06842.7 EIW77491.1 - 1.5e-17 62.7 1.2 1.9e-17 62.4 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DUF805 PF05656.9 EIW77491.1 - 0.1 12.4 0.7 0.11 12.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF805) SMC_N PF02463.14 EIW77492.1 - 2.8e-66 222.8 1.7 8.2e-66 221.3 1.2 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EIW77492.1 - 9.2e-23 80.4 0.3 9.2e-23 80.4 0.2 2.7 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EIW77492.1 - 4.5e-14 53.2 14.2 4.5e-14 53.2 9.9 5.6 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 EIW77492.1 - 2e-13 50.9 7.0 3.3e-06 27.2 0.1 3.2 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EIW77492.1 - 3.1e-05 23.4 0.0 9.4e-05 21.8 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EIW77492.1 - 0.011 14.9 16.5 0.26 10.4 1.4 4.5 3 2 2 5 5 5 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 EIW77492.1 - 0.014 15.7 0.2 0.014 15.7 0.1 5.7 3 2 1 4 4 4 0 ABC transporter DUF262 PF03235.9 EIW77493.1 - 5e-09 36.4 0.2 5e-09 36.4 0.1 1.8 1 1 1 2 2 2 1 Protein of unknown function DUF262 AT_hook PF02178.14 EIW77494.1 - 0.016 14.7 4.1 0.016 14.7 2.8 2.4 3 0 0 3 3 3 0 AT hook motif PBP1_TM PF14812.1 EIW77494.1 - 0.21 11.9 4.9 0.4 11.0 3.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cut8_N PF14482.1 EIW77494.1 - 8.1 6.5 8.8 88 3.2 4.8 2.9 2 1 0 2 2 2 0 Cut8 proteasome-binding domain Glyco_hydro_88 PF07470.8 EIW77495.1 - 2.6e-20 72.7 0.9 3.7e-20 72.2 0.6 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Pol_alpha_B_N PF08418.5 EIW77495.1 - 2.5 7.5 10.5 3.8 6.9 7.3 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal AHS2 PF02626.10 EIW77496.1 - 2.3e-66 223.8 0.0 1.9e-65 220.8 0.0 2.3 2 1 0 2 2 2 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 EIW77496.1 - 4.5e-41 140.4 0.0 2.1e-28 99.0 0.0 3.2 2 1 1 3 3 3 2 Carbamoyl-phosphate synthase L chain, ATP binding domain AHS1 PF02682.11 EIW77496.1 - 1.6e-39 135.4 0.0 3.2e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 CPSase_L_chain PF00289.17 EIW77496.1 - 5.9e-32 110.0 0.0 3.3e-31 107.6 0.0 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EIW77496.1 - 3.6e-31 107.3 0.0 7.8e-31 106.2 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EIW77496.1 - 2e-08 34.2 0.0 7.8e-07 29.0 0.0 2.4 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EIW77496.1 - 5.5e-06 25.9 0.0 8.1e-05 22.0 0.0 2.1 1 1 1 2 2 2 1 D-ala D-ala ligase C-terminus Biotin_lipoyl PF00364.17 EIW77496.1 - 8.1e-06 25.3 1.3 4.7e-05 22.9 0.8 2.2 1 1 0 1 1 1 1 Biotin-requiring enzyme RimK PF08443.6 EIW77496.1 - 0.034 13.6 0.0 0.42 10.0 0.0 2.3 2 0 0 2 2 2 0 RimK-like ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EIW77496.1 - 0.13 11.8 0.6 0.76 9.4 0.1 2.3 2 0 0 2 2 2 0 Biotin-lipoyl like OPT PF03169.10 EIW77497.1 - 5e-196 652.8 64.3 5.7e-196 652.6 44.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF4083 PF13314.1 EIW77497.1 - 0.088 12.6 0.0 0.088 12.6 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Aldo_ket_red PF00248.16 EIW77498.1 - 1.9e-45 154.8 0.1 2.4e-45 154.5 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EIW77499.1 - 1.7e-42 145.2 0.0 2.2e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1737 PF08410.5 EIW77499.1 - 0.098 12.4 0.1 0.54 10.0 0.0 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1737) F-box-like PF12937.2 EIW77500.1 - 0.00035 20.2 0.2 0.00093 18.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIW77501.1 - 0.022 14.4 1.0 0.1 12.3 0.2 2.3 2 0 0 2 2 2 0 F-box-like LRR_8 PF13855.1 EIW77501.1 - 0.056 13.1 0.1 2 8.2 0.0 2.9 3 0 0 3 3 3 0 Leucine rich repeat FAD_binding_3 PF01494.14 EIW77502.1 - 3.8e-66 223.5 0.0 4.8e-66 223.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EIW77502.1 - 1.2e-05 24.4 0.2 2.7e-05 23.1 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EIW77502.1 - 2.2e-05 23.6 0.0 4.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EIW77502.1 - 4.4e-05 23.4 0.1 0.00015 21.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIW77502.1 - 5.1e-05 23.2 0.0 0.00015 21.7 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW77502.1 - 0.00018 20.5 2.4 0.0028 16.6 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EIW77502.1 - 0.00019 20.4 0.0 0.0003 19.7 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 EIW77502.1 - 0.00032 19.3 0.2 0.00074 18.0 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EIW77502.1 - 0.00092 19.3 0.0 0.0026 17.8 0.0 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIW77502.1 - 0.001 18.2 0.1 0.0019 17.3 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW77502.1 - 0.0012 19.2 0.1 0.2 12.0 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIW77502.1 - 0.0018 16.9 0.0 0.0042 15.7 0.0 1.6 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EIW77502.1 - 0.027 13.4 0.3 0.097 11.5 0.2 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 EIW77502.1 - 0.037 13.7 0.2 0.082 12.6 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding TrkA_N PF02254.13 EIW77502.1 - 0.066 13.2 0.1 3.6 7.6 0.0 2.9 3 0 0 3 3 3 0 TrkA-N domain Viral_coat PF00729.13 EIW77503.1 - 0.025 13.8 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Viral coat protein (S domain) Pro_isomerase PF00160.16 EIW77504.1 - 6.5e-45 153.1 0.1 7.4e-45 152.9 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD F-box-like PF12937.2 EIW77505.1 - 5.9e-05 22.7 0.0 0.00012 21.7 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW77505.1 - 0.096 12.3 0.6 3.3 7.4 0.1 3.3 3 1 0 3 3 3 0 F-box domain Ribosomal_60s PF00428.14 EIW77506.1 - 1e-26 93.1 10.6 1.3e-26 92.8 7.3 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein AIRC PF00731.15 EIW77506.1 - 2 7.7 4.6 0.92 8.7 1.7 1.6 1 1 1 2 2 2 0 AIR carboxylase dUTPase PF00692.14 EIW77507.1 - 0.12 11.8 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 dUTPase Oxidored_q4 PF00507.14 EIW77508.1 - 0.022 14.5 3.5 0.022 14.5 2.4 1.9 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Alpha_GJ PF03229.8 EIW77509.1 - 0.0042 17.4 0.4 0.013 15.8 0.2 1.9 1 1 0 1 1 1 1 Alphavirus glycoprotein J ABC2_membrane_3 PF12698.2 EIW77509.1 - 0.015 14.3 0.3 0.025 13.6 0.2 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein FixQ PF05545.6 EIW77509.1 - 6.4 6.5 8.6 0.55 9.9 2.6 1.7 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ LamB_YcsF PF03746.11 EIW77510.1 - 9.3e-72 241.0 0.0 1.1e-71 240.7 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family F-box-like PF12937.2 EIW77511.1 - 7.8e-06 25.5 0.1 4.1e-05 23.2 0.0 2.2 2 0 0 2 2 2 1 F-box-like Aldo_ket_red PF00248.16 EIW77512.1 - 2.4e-43 148.0 0.0 3e-43 147.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_Tnp_1 PF01527.15 EIW77512.1 - 0.071 13.0 1.0 12 5.9 0.0 2.9 2 1 0 2 2 2 0 Transposase Glyco_hydro_16 PF00722.16 EIW77513.1 - 2.2e-09 36.8 0.0 3.9e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Aldo_ket_red PF00248.16 EIW77514.1 - 4e-42 143.9 0.0 5.4e-42 143.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family zf-CCCH PF00642.19 EIW77515.1 - 0.032 13.9 10.5 0.48 10.1 0.7 2.3 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Dynamin_M PF01031.15 EIW77516.1 - 4.7e-28 97.8 0.0 3.7e-14 52.2 0.0 2.5 2 0 0 2 2 2 2 Dynamin central region Dynamin_N PF00350.18 EIW77516.1 - 1.5e-26 93.2 0.0 5.1e-26 91.4 0.0 1.9 1 1 0 1 1 1 1 Dynamin family GED PF02212.13 EIW77516.1 - 1.4e-09 37.7 3.0 2.7e-09 36.7 0.2 2.6 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EIW77516.1 - 0.00021 21.2 0.0 0.0019 18.1 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIW77516.1 - 0.03 14.8 0.0 0.08 13.4 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_28 PF13521.1 EIW77516.1 - 0.069 13.1 0.9 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EIW77516.1 - 0.099 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_12 PF13087.1 EIW77517.1 - 2.6e-39 134.7 0.0 6.4e-39 133.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EIW77517.1 - 1.7e-36 125.3 11.9 3.1e-13 50.0 0.0 7.0 6 0 0 6 6 5 4 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EIW77517.1 - 1.9e-28 99.6 31.5 1.1e-26 93.9 0.0 6.7 6 0 0 6 6 5 2 AAA domain AAA_19 PF13245.1 EIW77517.1 - 4.8e-21 74.3 2.7 1.4e-07 31.1 0.0 4.9 4 0 0 4 4 4 4 Part of AAA domain AAA_5 PF07728.9 EIW77517.1 - 2.1e-13 50.2 2.0 0.016 14.9 0.0 5.3 5 0 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EIW77517.1 - 2.3e-11 44.5 19.1 0.017 15.8 0.0 6.1 6 0 0 6 6 4 4 AAA domain AAA_30 PF13604.1 EIW77517.1 - 4.3e-11 42.7 16.5 4.4e-05 23.1 0.0 6.3 6 1 0 6 6 5 4 AAA domain AAA_22 PF13401.1 EIW77517.1 - 1.6e-10 41.2 19.0 0.047 13.8 0.0 8.6 7 2 0 7 7 7 4 AAA domain Mg_chelatase PF01078.16 EIW77517.1 - 2.5e-10 39.8 1.8 0.13 11.4 0.0 5.0 6 0 0 6 6 5 4 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EIW77517.1 - 2.9e-10 39.8 0.1 0.73 9.2 0.0 4.8 4 0 0 4 4 4 4 IstB-like ATP binding protein AAA_16 PF13191.1 EIW77517.1 - 4.6e-10 39.7 18.9 0.018 15.0 0.1 6.7 6 0 0 6 6 6 3 AAA ATPase domain AAA_18 PF13238.1 EIW77517.1 - 3.3e-09 37.1 11.1 0.15 12.4 0.0 5.8 5 0 0 5 5 4 4 AAA domain RNA_helicase PF00910.17 EIW77517.1 - 1.5e-08 34.7 0.3 1.5 9.0 0.0 5.0 4 0 0 4 4 4 2 RNA helicase Viral_helicase1 PF01443.13 EIW77517.1 - 4.3e-08 32.9 0.1 0.088 12.3 0.0 5.6 6 0 0 6 6 6 1 Viral (Superfamily 1) RNA helicase Sigma54_activat PF00158.21 EIW77517.1 - 2.4e-07 30.3 2.0 1.7 8.0 0.0 5.4 4 1 0 4 4 4 3 Sigma-54 interaction domain Torsin PF06309.6 EIW77517.1 - 5.1e-07 29.6 0.1 3 7.7 0.0 5.2 5 0 0 5 5 4 1 Torsin AAA_24 PF13479.1 EIW77517.1 - 5.8e-06 26.0 4.5 1.3 8.5 0.0 5.0 4 0 0 4 4 4 3 AAA domain AAA_25 PF13481.1 EIW77517.1 - 7.4e-06 25.5 1.4 0.2 11.0 0.0 5.1 4 0 0 4 4 4 1 AAA domain AAA_33 PF13671.1 EIW77517.1 - 0.00034 20.5 14.8 1.6 8.6 0.0 5.5 5 0 0 5 5 4 3 AAA domain DUF2075 PF09848.4 EIW77517.1 - 0.00055 19.0 0.0 0.00055 19.0 0.0 6.8 7 2 0 8 8 7 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 EIW77517.1 - 0.0027 17.3 1.4 14 5.2 0.0 4.3 4 0 0 4 4 4 0 NACHT domain NTPase_1 PF03266.10 EIW77517.1 - 0.0056 16.4 2.5 9.2 5.9 0.0 4.2 4 0 0 4 4 4 0 NTPase AAA_29 PF13555.1 EIW77517.1 - 0.013 15.0 0.8 46 3.6 0.0 4.2 4 0 0 4 4 4 0 P-loop containing region of AAA domain OmpH PF03938.9 EIW77517.1 - 0.021 14.7 0.3 0.021 14.7 0.2 3.7 3 1 0 3 3 1 0 Outer membrane protein (OmpH-like) DUF572 PF04502.8 EIW77517.1 - 0.023 13.9 25.1 0.069 12.3 1.1 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF572) KaiC PF06745.8 EIW77517.1 - 0.066 12.3 12.3 0.8 8.7 0.0 5.1 5 0 0 5 5 4 0 KaiC AAA_28 PF13521.1 EIW77517.1 - 0.41 10.5 25.8 2.1 8.2 0.0 6.3 7 0 0 7 7 4 0 AAA domain Dynamin_N PF00350.18 EIW77518.1 - 1.4e-26 93.2 0.0 3.3e-26 92.1 0.0 1.6 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EIW77518.1 - 2.8e-26 92.0 0.0 5.9e-15 54.8 0.0 2.6 3 0 0 3 3 3 2 Dynamin central region GED PF02212.13 EIW77518.1 - 1.1e-09 37.9 0.1 3.2e-09 36.5 0.1 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EIW77518.1 - 0.00067 19.6 0.0 0.0049 16.8 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIW77518.1 - 0.026 15.0 0.0 0.055 13.9 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_28 PF13521.1 EIW77518.1 - 0.035 14.0 0.1 0.19 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain TAFH PF07531.9 EIW77518.1 - 0.097 12.3 0.1 1.1 8.9 0.0 2.7 2 1 1 3 3 3 0 NHR1 homology to TAF AAA_29 PF13555.1 EIW77518.1 - 0.12 11.9 0.2 0.24 10.9 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Methyltransf_2 PF00891.13 EIW77519.1 - 3.7e-23 81.9 0.0 7e-23 81.0 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EIW77519.1 - 9.1e-05 23.0 0.0 0.00029 21.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW77519.1 - 0.0012 19.2 0.0 0.004 17.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIW77519.1 - 0.009 15.0 0.0 0.027 13.5 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase GidB PF02527.10 EIW77519.1 - 0.016 14.3 0.0 0.037 13.1 0.0 1.5 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G HTH_IclR PF09339.5 EIW77519.1 - 0.017 14.7 0.1 0.037 13.6 0.1 1.5 1 0 0 1 1 1 0 IclR helix-turn-helix domain Methyltransf_31 PF13847.1 EIW77519.1 - 0.017 14.6 0.0 0.04 13.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EIW77519.1 - 0.019 14.3 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain RPA_C PF08784.6 EIW77519.1 - 0.033 14.5 0.0 0.079 13.3 0.0 1.6 1 0 0 1 1 1 0 Replication protein A C terminal Methyltransf_23 PF13489.1 EIW77519.1 - 0.034 13.8 0.0 0.083 12.6 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Dak1 PF02733.12 EIW77520.1 - 1e-80 270.7 1.2 1.6e-80 270.1 0.8 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EIW77520.1 - 1.7e-39 135.3 4.8 1.7e-39 135.3 3.3 1.8 2 0 0 2 2 2 1 DAK2 domain Methyltransf_2 PF00891.13 EIW77523.1 - 1.9e-27 96.0 0.0 3.6e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 EIW77523.1 - 1.2e-05 25.7 0.0 5.2e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW77523.1 - 1.5e-05 25.5 0.0 3.2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW77523.1 - 0.0011 18.7 0.0 0.002 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW77523.1 - 0.0016 18.0 0.0 0.0051 16.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EIW77523.1 - 0.015 14.6 0.0 0.031 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.7 EIW77523.1 - 0.023 15.1 0.0 0.062 13.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain HTH_IclR PF09339.5 EIW77523.1 - 0.051 13.1 0.1 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 IclR helix-turn-helix domain FAD_binding_3 PF01494.14 EIW77525.1 - 2.7e-32 112.2 0.0 4.4e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Cauli_VI PF01693.11 EIW77526.1 - 4.2e-07 29.8 0.5 6.9e-07 29.1 0.4 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin F-box-like PF12937.2 EIW77527.1 - 2.5e-09 36.6 3.1 6.4e-09 35.3 2.2 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIW77527.1 - 0.046 13.3 2.9 0.37 10.4 0.1 3.7 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EIW77527.1 - 0.28 11.5 2.8 10 6.8 0.1 4.4 4 0 0 4 4 4 0 Leucine rich repeat Flavin_Reduct PF01613.13 EIW77529.1 - 0.04 13.7 0.2 0.053 13.3 0.1 1.2 1 0 0 1 1 1 0 Flavin reductase like domain RRM_1 PF00076.17 EIW77530.1 - 2.6e-07 30.1 0.0 1.9e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW77530.1 - 0.00057 19.8 0.0 0.0016 18.4 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW77530.1 - 0.13 12.1 0.1 9.4 6.1 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BTB PF00651.26 EIW77531.1 - 4.1e-10 39.6 0.0 8.5e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Toxin_21 PF08091.6 EIW77532.1 - 0.0013 18.3 1.1 0.0037 16.9 0.8 1.7 1 0 0 1 1 1 1 Spider insecticidal peptide DUF869 PF05911.6 EIW77533.1 - 0.00076 17.8 6.9 0.001 17.3 4.8 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) EzrA PF06160.7 EIW77533.1 - 0.018 13.2 4.8 0.031 12.4 3.3 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA MAD PF05557.8 EIW77533.1 - 0.045 11.8 10.4 0.064 11.3 7.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DUF607 PF04678.8 EIW77533.1 - 0.12 12.2 2.1 1.1 9.1 0.0 2.5 1 1 0 2 2 2 0 Protein of unknown function, DUF607 Prefoldin PF02996.12 EIW77533.1 - 0.18 11.4 6.3 8.8 6.0 0.1 3.3 2 1 0 3 3 3 0 Prefoldin subunit Reo_sigmaC PF04582.7 EIW77533.1 - 0.2 10.7 9.4 0.067 12.3 2.7 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 EIW77533.1 - 0.26 11.1 11.1 0.051 13.4 0.5 3.3 2 2 1 3 3 3 0 Tropomyosin like Snf7 PF03357.16 EIW77533.1 - 0.32 10.3 5.0 1.1 8.6 3.5 1.8 1 1 0 1 1 1 0 Snf7 DUF1664 PF07889.7 EIW77533.1 - 0.87 9.3 3.9 5.5 6.7 0.3 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Flagellin_N PF00669.15 EIW77533.1 - 1.7 8.4 7.1 2.5 7.9 0.5 2.7 1 1 2 3 3 3 0 Bacterial flagellin N-terminal helical region DivIVA PF05103.8 EIW77533.1 - 1.9 8.5 8.4 0.37 10.8 0.5 2.8 3 0 0 3 3 3 0 DivIVA protein Snapin_Pallidin PF14712.1 EIW77533.1 - 2.2 8.6 8.1 40 4.6 0.0 4.0 4 1 1 5 5 5 0 Snapin/Pallidin ATG16 PF08614.6 EIW77533.1 - 2.3 8.0 9.8 4.9 6.9 6.7 1.6 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 EIW77533.1 - 2.5 7.0 9.5 11 4.9 5.4 1.9 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF1515 PF07439.6 EIW77533.1 - 2.6 7.8 6.4 24 4.8 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) Phage_GPO PF05929.6 EIW77533.1 - 2.7 7.1 8.3 0.94 8.6 2.9 2.2 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Phage_GP20 PF06810.6 EIW77533.1 - 5.2 6.4 6.7 0.29 10.5 0.3 2.0 2 1 0 2 2 2 0 Phage minor structural protein GP20 Spectrin PF00435.16 EIW77533.1 - 7.5 6.8 7.9 12 6.2 0.9 3.0 1 1 1 2 2 2 0 Spectrin repeat Pkinase PF00069.20 EIW77534.1 - 4.3e-49 167.0 0.0 1.9e-47 161.6 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW77534.1 - 5e-26 91.3 0.0 2.5e-25 89.0 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW77534.1 - 1.1e-06 27.8 0.0 2.6e-06 26.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like FHA PF00498.21 EIW77534.1 - 2.3e-05 24.4 0.0 5.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 FHA domain Tower PF09121.5 EIW77535.1 - 0.048 13.5 2.3 5.7 6.9 0.2 2.5 2 0 0 2 2 2 0 Tower Cwf_Cwc_15 PF04889.7 EIW77535.1 - 1.2 8.7 20.3 0.17 11.5 6.1 2.8 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Sad1_UNC PF07738.8 EIW77536.1 - 2.4e-17 62.9 0.0 2.7e-14 53.1 0.0 2.3 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal Mito_fiss_reg PF05308.6 EIW77536.1 - 1.9 7.7 8.5 3.8 6.7 5.9 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Transposase_21 PF02992.9 EIW77539.1 - 2.8e-14 52.7 0.0 3.5e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 DUF1258 PF06869.7 EIW77539.1 - 0.02 14.0 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) zf-C4_ClpX PF06689.8 EIW77539.1 - 0.062 12.8 0.3 0.12 11.9 0.2 1.4 1 0 0 1 1 1 0 ClpX C4-type zinc finger Cnd1 PF12717.2 EIW77541.1 - 0.004 17.0 0.1 0.0083 15.9 0.1 1.4 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 DUF2018 PF09442.5 EIW77541.1 - 0.0094 16.5 0.9 0.018 15.5 0.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2018) DUF310 PF03750.8 EIW77541.1 - 0.032 14.4 0.3 0.17 12.0 0.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF310) DUF2408 PF10303.4 EIW77541.1 - 0.056 13.5 1.6 0.077 13.1 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF342 PF03961.8 EIW77541.1 - 0.075 11.4 2.6 0.085 11.2 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Mitovir_RNA_pol PF05919.6 EIW77541.1 - 0.082 11.8 1.7 0.097 11.6 1.2 1.0 1 0 0 1 1 1 0 Mitovirus RNA-dependent RNA polymerase N6_N4_Mtase PF01555.13 EIW77541.1 - 0.13 11.7 0.9 0.13 11.7 0.6 1.1 1 0 0 1 1 1 0 DNA methylase NEP PF10167.4 EIW77541.1 - 0.51 10.0 4.0 13 5.4 0.1 3.0 2 1 1 3 3 3 0 Uncharacterised conserved protein IncA PF04156.9 EIW77541.1 - 0.92 9.0 5.4 1.3 8.6 3.7 1.3 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EIW77541.1 - 5.4 5.9 10.2 7.3 5.5 7.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CDC45 PF02724.9 EIW77542.1 - 0.019 13.0 3.3 0.031 12.3 2.3 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF641 PF04859.7 EIW77542.1 - 0.17 11.6 2.9 0.39 10.4 2.0 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Inhibitor_I53 PF11714.3 EIW77542.1 - 3.3 7.7 5.9 6.3 6.8 4.1 1.5 1 0 0 1 1 1 0 Thrombin inhibitor Madanin Pico_P1A PF02226.11 EIW77544.1 - 0.1 12.3 0.2 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 Picornavirus coat protein (VP4) GTP_EFTU_D2 PF03144.20 EIW77546.1 - 1.8 8.7 4.4 40 4.4 0.9 3.2 1 1 0 2 2 2 0 Elongation factor Tu domain 2 FAD_binding_3 PF01494.14 EIW77547.1 - 1.2e-34 119.9 0.1 1.5e-34 119.6 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EIW77547.1 - 2.9e-05 23.1 0.1 0.035 12.9 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 EIW77547.1 - 3.7e-05 23.8 0.0 6.4e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW77547.1 - 8.8e-05 22.8 0.1 0.48 10.8 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW77547.1 - 0.00077 19.3 0.0 0.003 17.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIW77547.1 - 0.00093 18.3 0.1 0.93 8.4 0.0 2.0 2 0 0 2 2 2 2 FAD dependent oxidoreductase DAO PF01266.19 EIW77547.1 - 0.0018 17.2 0.2 0.12 11.2 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EIW77547.1 - 0.002 17.2 0.0 0.0041 16.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.19 EIW77547.1 - 0.0054 15.8 0.0 0.17 10.9 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EIW77547.1 - 0.0064 16.4 0.0 0.019 14.9 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EIW77547.1 - 0.0069 14.8 0.0 0.62 8.4 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein DUF4309 PF14172.1 EIW77547.1 - 0.11 12.5 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4309) F-box-like PF12937.2 EIW77548.1 - 0.00022 20.9 2.7 0.099 12.3 0.0 3.9 4 1 0 4 4 4 2 F-box-like DUF4027 PF13219.1 EIW77548.1 - 0.069 12.5 0.1 19 4.7 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4027) eIF_4G1 PF12152.3 EIW77550.1 - 1.1e-12 47.6 0.0 1.3e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 DUF1708 PF08101.6 EIW77551.1 - 1.7e-16 60.1 0.0 5.3e-16 58.4 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1708) FAD_binding_3 PF01494.14 EIW77554.1 - 1.1e-05 24.6 0.0 1.9e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EIW77556.1 - 8.3e-69 232.3 0.0 1.1e-68 231.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIW77556.1 - 4.3e-05 23.4 0.1 0.00016 21.6 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW77556.1 - 0.00018 20.6 0.0 0.00033 19.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EIW77556.1 - 0.00065 18.8 0.7 0.0055 15.8 0.5 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIW77556.1 - 0.00089 19.3 0.5 0.0069 16.4 0.3 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW77556.1 - 0.0015 18.8 0.2 0.22 11.9 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW77556.1 - 0.0026 16.6 0.1 0.034 13.0 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EIW77556.1 - 0.007 14.8 0.1 0.14 10.6 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 EIW77556.1 - 0.0096 14.8 0.9 0.054 12.3 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW77556.1 - 0.011 15.7 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EIW77556.1 - 0.023 13.7 0.3 1.3 8.0 0.0 2.8 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Pericardin_rpt PF07054.6 EIW77557.1 - 0.0034 17.2 5.8 13 5.7 0.1 4.2 2 2 2 4 4 4 4 Pericardin like repeat EPL1 PF10513.4 EIW77559.1 - 1e-14 55.0 4.1 1.7e-14 54.3 2.8 1.3 1 0 0 1 1 1 1 Enhancer of polycomb-like bZIP_2 PF07716.10 EIW77562.1 - 0.0053 16.5 1.3 0.011 15.5 0.9 1.5 1 0 0 1 1 1 1 Basic region leucine zipper TMCO5 PF14992.1 EIW77562.1 - 0.021 14.0 0.4 0.026 13.6 0.2 1.1 1 0 0 1 1 1 0 TMCO5 family FlaC_arch PF05377.6 EIW77562.1 - 0.024 14.4 0.2 0.038 13.8 0.2 1.3 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) bZIP_1 PF00170.16 EIW77562.1 - 0.041 13.8 0.1 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 bZIP transcription factor CENP-Q PF13094.1 EIW77562.1 - 0.062 13.3 0.1 0.077 13.0 0.1 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TMF_DNA_bd PF12329.3 EIW77562.1 - 0.078 12.8 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.6 EIW77562.1 - 0.15 10.7 0.1 0.2 10.3 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) zf-PARP PF00645.13 EIW77565.1 - 5.2e-19 68.2 0.0 8.4e-19 67.6 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-RVT PF13966.1 EIW77566.1 - 0.013 15.8 0.0 0.017 15.3 0.0 1.2 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase DUF3039 PF11238.3 EIW77566.1 - 0.02 14.3 0.1 0.034 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) Ded_cyto PF06920.8 EIW77566.1 - 0.12 11.6 0.0 0.15 11.3 0.0 1.1 1 0 0 1 1 1 0 Dedicator of cytokinesis DUF4349 PF14257.1 EIW77567.1 - 0.92 8.6 4.6 1.1 8.4 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) COX7B PF05392.6 EIW77568.1 - 0.12 12.0 0.0 0.55 9.8 0.0 2.0 2 1 0 2 2 2 0 Cytochrome C oxidase chain VIIB Sad1_UNC PF07738.8 EIW77572.1 - 1.2e-10 41.3 0.3 4.3e-09 36.2 0.0 2.8 2 1 0 2 2 2 1 Sad1 / UNC-like C-terminal Pkinase PF00069.20 EIW77573.1 - 3.8e-35 121.2 0.0 3.2e-19 69.0 0.0 3.6 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW77573.1 - 2.4e-15 56.3 0.0 3.4e-10 39.4 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase DUF4218 PF13960.1 EIW77575.1 - 6.9e-05 22.2 0.0 0.00011 21.6 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4218) IRF-3 PF10401.4 EIW77575.1 - 0.034 13.7 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Interferon-regulatory factor 3 BAR_3_WASP_bdg PF10456.4 EIW77575.1 - 0.076 12.2 0.1 0.099 11.8 0.0 1.1 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein CbbQ_C PF08406.5 EIW77575.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 CbbQ/NirQ/NorQ C-terminal MAT1 PF06391.8 EIW77579.1 - 0.003 17.1 0.9 0.0042 16.6 0.6 1.2 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 RCSD PF05177.7 EIW77580.1 - 0.038 14.4 0.2 0.048 14.1 0.2 1.1 1 0 0 1 1 1 0 RCSD region RFC1 PF08519.7 EIW77583.1 - 0.0052 16.5 0.0 0.013 15.2 0.0 1.6 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain Aldedh PF00171.17 EIW77585.1 - 0.00017 20.0 0.1 0.17 10.1 0.0 2.3 2 0 0 2 2 2 2 Aldehyde dehydrogenase family PVL_ORF50 PF07768.6 EIW77586.1 - 0.17 11.8 0.0 0.3 11.1 0.0 1.3 1 0 0 1 1 1 0 PVL ORF-50-like family Cyclin_N PF00134.18 EIW77587.1 - 1.1e-10 41.1 0.0 1.5e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EIW77587.1 - 2.3e-08 34.6 0.0 2.7e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin PI-PLC-X PF00388.14 EIW77588.1 - 0.026 13.9 0.0 0.036 13.4 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain BTB PF00651.26 EIW77589.1 - 0.0089 16.0 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Eaf7 PF07904.8 EIW77589.1 - 0.018 15.0 0.1 0.072 13.0 0.0 2.1 3 0 0 3 3 3 0 Chromatin modification-related protein EAF7 Pro_CA PF00484.14 EIW77592.1 - 3.9e-26 91.8 0.0 5.7e-26 91.3 0.0 1.3 1 1 0 1 1 1 1 Carbonic anhydrase N_Asn_amidohyd PF14736.1 EIW77592.1 - 0.018 13.9 0.1 0.75 8.6 0.0 2.1 2 0 0 2 2 2 0 Protein N-terminal asparagine amidohydrolase Hydantoinase_A PF01968.13 EIW77594.1 - 1e-91 307.0 0.0 1.4e-91 306.6 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EIW77594.1 - 0.032 13.7 0.3 1.7 8.1 0.1 2.4 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EIW77594.1 - 0.1 10.9 0.0 0.15 10.3 0.0 1.2 1 0 0 1 1 1 0 MutL protein Miro PF08477.8 EIW77595.1 - 4.6e-07 30.3 0.0 1.7e-06 28.5 0.0 2.0 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIW77595.1 - 2.1e-06 27.6 0.0 4.2e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EIW77595.1 - 0.00025 19.8 0.0 0.18 10.4 0.0 2.6 3 0 0 3 3 3 2 G-protein alpha subunit Arf PF00025.16 EIW77595.1 - 0.00057 19.1 0.1 0.0048 16.1 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_17 PF13207.1 EIW77595.1 - 0.0018 19.0 0.0 0.21 12.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EIW77595.1 - 0.0042 16.8 0.2 0.035 13.8 0.0 2.2 2 1 0 2 2 2 1 NTPase GTP_EFTU PF00009.22 EIW77595.1 - 0.0076 15.6 0.2 1.6 8.1 0.0 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain MobB PF03205.9 EIW77595.1 - 0.012 15.3 0.1 0.031 13.9 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EIW77595.1 - 0.022 14.3 0.2 2.6 7.5 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EIW77595.1 - 0.033 14.3 0.0 0.084 13.0 0.0 1.7 1 1 1 2 2 2 0 AAA domain PduV-EutP PF10662.4 EIW77595.1 - 0.035 13.5 0.0 0.16 11.4 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EIW77595.1 - 0.043 13.5 0.2 0.19 11.3 0.1 2.3 1 1 0 1 1 1 0 Archaeal ATPase FeoB_N PF02421.13 EIW77595.1 - 0.058 12.6 0.3 0.38 10.0 0.0 2.4 3 0 0 3 3 3 0 Ferrous iron transport protein B Tricorn_C1 PF14684.1 EIW77595.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Tricorn protease C1 domain DUF4419 PF14388.1 EIW77596.1 - 9.9e-98 327.0 0.0 1.2e-97 326.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Pardaxin PF07425.6 EIW77596.1 - 0.003 16.9 1.2 0.003 16.9 0.8 2.2 1 1 1 2 2 2 1 Pardaxin GTP_EFTU PF00009.22 EIW77598.1 - 9.3e-56 188.2 0.0 1.4e-55 187.6 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EIW77598.1 - 3e-30 103.8 0.0 5.7e-30 102.9 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EIW77598.1 - 4.4e-30 103.6 0.1 4.4e-20 71.4 0.0 3.1 3 0 0 3 3 3 2 Elongation factor G, domain IV EFG_C PF00679.19 EIW77598.1 - 4.5e-21 74.5 0.1 1.3e-20 73.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EIW77598.1 - 1.9e-12 47.1 0.0 4.3e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DsbD_2 PF13386.1 EIW77599.1 - 0.009 15.7 1.5 0.011 15.5 1.1 1.1 1 0 0 1 1 1 1 Cytochrome C biogenesis protein transmembrane region GST_N_3 PF13417.1 EIW77600.1 - 2.9e-12 46.6 0.0 5.5e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW77600.1 - 7.8e-06 25.8 0.0 1.3e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW77600.1 - 2.6e-05 24.0 0.1 5.1e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW77600.1 - 0.00011 22.2 0.0 0.00029 20.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIW77600.1 - 0.00045 20.6 0.0 0.00066 20.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW77600.1 - 0.00056 19.8 0.0 0.0018 18.2 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain p450 PF00067.17 EIW77601.1 - 9.5e-81 271.6 0.0 1.2e-80 271.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW77602.1 - 2.7e-80 270.1 0.0 3.4e-80 269.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Inositol_P PF00459.20 EIW77603.1 - 8.8e-50 169.5 0.2 1.7e-49 168.5 0.1 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family HET PF06985.6 EIW77604.1 - 1e-18 67.8 1.3 1.3e-14 54.5 0.0 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Pyr_redox_3 PF13738.1 EIW77605.1 - 1.7e-18 67.4 0.0 1.9e-17 64.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIW77605.1 - 3e-13 48.8 0.1 9.6e-13 47.1 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EIW77605.1 - 1.3e-09 37.9 0.0 1.4e-08 34.6 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EIW77605.1 - 1.1e-07 31.1 0.0 5.8e-05 22.1 0.0 2.4 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EIW77605.1 - 1.2e-05 24.4 0.0 0.00084 18.3 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIW77605.1 - 2.7e-05 24.1 0.1 0.49 10.2 0.0 3.1 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW77605.1 - 0.0033 16.3 0.0 0.0079 15.0 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EIW77605.1 - 0.0054 15.8 0.0 0.018 14.1 0.0 1.8 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.14 EIW77605.1 - 0.006 15.7 0.1 0.013 14.7 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 EIW77605.1 - 0.061 11.7 0.2 1.4 7.2 0.0 2.7 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox PF00070.22 EIW77605.1 - 0.12 12.8 0.0 18 5.7 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Transposase_21 PF02992.9 EIW77607.1 - 4.8e-08 32.3 0.0 1.1e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EIW77607.1 - 0.039 13.3 0.1 0.08 12.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Pyr_redox_3 PF13738.1 EIW77608.1 - 2.9e-25 89.5 0.0 6.2e-25 88.4 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW77608.1 - 7e-13 48.2 0.0 1.1e-09 37.7 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EIW77608.1 - 1.4e-10 39.9 0.0 8.5e-10 37.4 0.0 2.0 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EIW77608.1 - 1.8e-09 37.7 0.0 0.00021 21.2 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW77608.1 - 2.3e-08 33.9 0.0 2.3e-06 27.5 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIW77608.1 - 0.00023 21.4 0.0 0.55 10.6 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW77608.1 - 0.024 13.5 2.0 0.27 10.0 0.1 2.8 2 1 0 3 3 3 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EIW77608.1 - 0.025 13.7 0.0 0.048 12.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EIW77608.1 - 0.027 14.5 0.0 0.059 13.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_2 PF00890.19 EIW77608.1 - 0.03 13.1 0.0 0.055 12.3 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 EIW77608.1 - 0.033 13.9 2.6 1.1 9.0 0.1 3.6 3 1 0 3 3 3 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 EIW77608.1 - 0.047 12.7 0.6 1.2 8.1 0.0 2.4 1 1 1 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EIW77608.1 - 0.074 13.3 0.0 3.3 8.0 0.0 3.0 3 0 0 3 3 3 0 Putative NAD(P)-binding Thi4 PF01946.12 EIW77608.1 - 0.22 10.5 0.4 0.69 8.9 0.0 2.0 3 0 0 3 3 3 0 Thi4 family Pyr_redox_3 PF13738.1 EIW77609.1 - 1.1e-18 68.0 0.0 4.8e-18 65.9 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIW77609.1 - 4.7e-12 44.8 0.1 2.1e-11 42.7 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EIW77609.1 - 5.4e-11 41.9 0.0 1.4e-07 30.7 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EIW77609.1 - 1.8e-10 40.6 0.1 1.3e-09 37.8 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIW77609.1 - 2.9e-07 29.7 0.4 0.00013 20.9 0.0 3.0 3 1 1 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIW77609.1 - 2.3e-06 27.6 0.0 0.001 19.0 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW77609.1 - 0.00032 19.6 0.0 0.00064 18.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EIW77609.1 - 0.00034 19.7 0.1 0.0023 17.0 0.0 2.2 3 0 0 3 3 3 1 Thi4 family 2-Hacid_dh_C PF02826.14 EIW77609.1 - 0.0086 15.2 0.0 0.018 14.1 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EIW77609.1 - 0.015 15.0 0.1 0.76 9.5 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.17 EIW77609.1 - 0.051 12.4 0.0 0.68 8.7 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 EIW77609.1 - 0.059 11.8 0.4 0.36 9.2 0.0 2.4 4 0 0 4 4 4 0 HI0933-like protein DUF3940 PF13076.1 EIW77609.1 - 0.096 12.2 1.1 2.2 7.9 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3940) Polysacc_deac_1 PF01522.16 EIW77610.1 - 1.7e-28 98.7 0.0 4e-28 97.5 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide deacetylase GRAM PF02893.15 EIW77611.1 - 8e-17 60.5 0.0 2e-16 59.2 0.0 1.7 1 0 0 1 1 1 1 GRAM domain Polysacc_deac_1 PF01522.16 EIW77612.1 - 1.1e-27 96.1 0.0 1.9e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_1 PF01522.16 EIW77613.1 - 2.7e-27 94.8 0.0 5.6e-27 93.8 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase GPI2 PF06432.6 EIW77618.1 - 0.049 12.9 8.0 0.066 12.5 5.5 1.4 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase DUF3568 PF12092.3 EIW77618.1 - 0.092 12.4 5.2 0.25 11.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3568) DIOX_N PF14226.1 EIW77619.1 - 4.6e-24 85.1 0.0 6.9e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIW77619.1 - 1.1e-19 70.5 0.0 1.9e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CxxCxxCC PF03692.10 EIW77620.1 - 0.041 14.3 0.1 0.063 13.7 0.1 1.4 1 1 0 1 1 1 0 Putative zinc- or iron-chelating domain MMR_HSR1 PF01926.18 EIW77621.1 - 3.2e-05 23.8 0.0 4.2e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIW77621.1 - 0.00012 22.5 0.0 0.00014 22.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW77621.1 - 0.0016 17.7 0.0 0.0021 17.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MobB PF03205.9 EIW77621.1 - 0.0051 16.5 0.1 0.0068 16.1 0.1 1.5 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EIW77621.1 - 0.0073 16.0 0.0 0.01 15.5 0.0 1.4 1 1 0 1 1 1 1 Archaeal ATPase PduV-EutP PF10662.4 EIW77621.1 - 0.017 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 EIW77621.1 - 0.049 14.4 0.1 0.066 14.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EIW77621.1 - 0.073 12.3 0.0 0.1 11.8 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.1 EIW77621.1 - 0.11 12.6 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EIW77621.1 - 0.13 12.2 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Peptidase_M48 PF01435.13 EIW77622.1 - 1.8e-24 86.5 0.0 3.7e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M48 GST_N_3 PF13417.1 EIW77623.1 - 5.2e-12 45.8 0.0 1.1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW77623.1 - 5.4e-07 29.4 0.2 1e-06 28.5 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW77623.1 - 1.2e-05 25.1 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW77623.1 - 5.9e-05 23.1 0.0 0.00016 21.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW77623.1 - 0.00038 20.3 0.0 0.0011 18.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW77623.1 - 0.0052 17.2 0.0 0.0087 16.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIW77624.1 - 4.7e-09 36.3 0.0 6.6e-08 32.6 0.0 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW77624.1 - 1.1e-06 28.3 0.1 2.8e-06 27.1 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW77624.1 - 0.00025 21.4 0.0 0.00045 20.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW77624.1 - 0.00028 20.9 0.0 0.00066 19.7 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW77624.1 - 0.00054 19.8 0.0 0.00087 19.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW77624.1 - 0.0019 18.1 0.0 0.0077 16.1 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain p450 PF00067.17 EIW77626.1 - 2.1e-53 181.5 0.0 7.9e-53 179.6 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 DUF3533 PF12051.3 EIW77627.1 - 1.6e-71 241.0 4.5 2e-71 240.7 3.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) DUF4066 PF13278.1 EIW77628.1 - 2.9e-11 42.9 0.3 1.4e-10 40.7 0.2 2.0 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EIW77628.1 - 0.071 12.5 0.0 0.76 9.2 0.0 2.1 2 0 0 2 2 2 0 DJ-1/PfpI family Cpn60_TCP1 PF00118.19 EIW77631.1 - 4.9e-116 388.2 6.5 5.6e-116 388.0 4.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family polyprenyl_synt PF00348.12 EIW77632.1 - 2e-63 213.6 0.0 3.3e-63 212.9 0.0 1.3 1 0 0 1 1 1 1 Polyprenyl synthetase Pkinase PF00069.20 EIW77634.1 - 1.5e-67 227.5 0.0 1.8e-67 227.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW77634.1 - 1.3e-36 126.0 0.0 1.7e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EIW77634.1 - 2.8e-15 56.1 0.2 6.8e-15 54.9 0.1 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EIW77634.1 - 2.3e-10 39.9 0.0 4.5e-10 38.9 0.0 1.5 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EIW77634.1 - 0.00058 19.6 0.0 0.0014 18.4 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family YebG PF07130.7 EIW77634.1 - 0.03 14.0 0.3 0.64 9.7 0.0 2.4 2 0 0 2 2 2 0 YebG protein Kdo PF06293.9 EIW77634.1 - 0.055 12.5 0.0 0.11 11.4 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EzrA PF06160.7 EIW77635.1 - 0.013 13.7 3.3 0.049 11.8 2.3 1.7 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Reo_sigmaC PF04582.7 EIW77635.1 - 0.018 14.2 11.3 0.38 9.8 4.3 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 EIW77635.1 - 0.018 12.3 3.9 0.024 12.0 2.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.7 EIW77635.1 - 0.027 14.2 7.8 0.19 11.5 0.3 2.6 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4455 PF14643.1 EIW77635.1 - 0.073 11.6 1.8 0.17 10.4 1.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4455) AF0941-like PF14591.1 EIW77635.1 - 0.11 12.6 1.1 0.72 9.9 0.1 2.2 2 0 0 2 2 2 0 AF0941-like DUF972 PF06156.8 EIW77635.1 - 0.21 11.9 3.2 6.3 7.1 0.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF1664 PF07889.7 EIW77635.1 - 0.23 11.2 5.1 1.3 8.8 0.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF4618 PF15397.1 EIW77635.1 - 0.29 10.4 4.2 4.8 6.4 0.4 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4618) DUF883 PF05957.8 EIW77635.1 - 0.42 11.0 4.5 1.7 9.1 0.5 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) ATG16 PF08614.6 EIW77635.1 - 0.9 9.3 7.6 44 3.8 6.9 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) KLRAQ PF10205.4 EIW77635.1 - 1 9.4 4.8 2.4 8.2 0.2 2.3 1 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein Phage_GPO PF05929.6 EIW77635.1 - 1.3 8.1 5.1 2 7.6 0.8 2.1 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase HALZ PF02183.13 EIW77635.1 - 4.7 7.0 7.1 1.4 8.6 0.1 3.0 4 0 0 4 4 4 0 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.4 EIW77635.1 - 4.7 7.0 9.2 1.6 8.5 1.5 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sad1_UNC PF07738.8 EIW77638.1 - 1.5e-19 70.1 0.0 3.6e-19 68.8 0.0 1.7 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal PLC-beta_C PF08703.5 EIW77641.1 - 0.12 12.1 10.9 0.055 13.1 4.4 2.1 2 0 0 2 2 2 0 PLC-beta C terminal ADIP PF11559.3 EIW77641.1 - 3.1 7.6 12.5 0.44 10.4 5.0 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Pkinase PF00069.20 EIW77642.1 - 2e-63 213.9 0.0 2.7e-63 213.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW77642.1 - 2.2e-34 118.7 0.0 3.2e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EIW77642.1 - 8.4e-15 54.6 0.4 1.5e-14 53.8 0.3 1.5 1 0 0 1 1 1 1 FHA domain Kdo PF06293.9 EIW77642.1 - 2.7e-05 23.3 0.0 5.2e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW77642.1 - 5e-05 23.1 0.0 0.039 13.6 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW77642.1 - 0.017 14.1 0.0 0.026 13.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like FlxA PF14282.1 EIW77644.1 - 0.25 11.3 5.5 0.53 10.2 3.8 1.5 1 0 0 1 1 1 0 FlxA-like protein Ubiq_cyt_C_chap PF03981.7 EIW77645.1 - 1.2e-25 89.9 0.0 3.4e-13 49.6 0.0 3.2 3 0 0 3 3 3 3 Ubiquinol-cytochrome C chaperone Terpene_synth_C PF03936.11 EIW77648.1 - 5.4e-08 32.3 0.0 8.4e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.17 EIW77649.1 - 4.4e-55 187.0 0.0 1.4e-54 185.3 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW77650.1 - 2.9e-43 148.0 0.0 1.2e-42 146.0 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EIW77652.1 - 0.0003 20.4 0.8 0.00081 19.0 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIW77652.1 - 0.05 13.2 0.4 0.19 11.4 0.3 2.1 1 0 0 1 1 1 0 F-box domain Trm112p PF03966.11 EIW77653.1 - 2.6e-18 66.1 0.0 7.7e-17 61.4 0.0 2.3 1 1 0 1 1 1 1 Trm112p-like protein zf-CHCC PF10276.4 EIW77653.1 - 0.016 15.0 0.2 0.029 14.2 0.1 1.3 1 0 0 1 1 1 0 Zinc-finger domain Trm112p PF03966.11 EIW77654.1 - 5.3e-12 45.9 0.0 1.2e-11 44.7 0.0 1.6 1 1 0 1 1 1 1 Trm112p-like protein AurF PF11583.3 EIW77654.1 - 0.017 14.0 0.0 0.025 13.5 0.0 1.1 1 0 0 1 1 1 0 P-aminobenzoate N-oxygenase AurF zf-NADH-PPase PF09297.6 EIW77654.1 - 0.082 12.4 0.8 0.15 11.6 0.6 1.4 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain DUF3675 PF12428.3 EIW77655.1 - 0.019 15.2 0.4 0.036 14.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) AhpC-TSA PF00578.16 EIW77657.1 - 2e-39 134.1 0.0 2.7e-39 133.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIW77657.1 - 1.9e-14 53.4 0.0 2.9e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EIW77657.1 - 1.3e-11 43.9 0.0 2.2e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin F-box-like PF12937.2 EIW77658.1 - 0.00012 21.7 0.8 0.00035 20.2 0.6 1.9 1 0 0 1 1 1 1 F-box-like Anemone_cytotox PF06369.7 EIW77661.1 - 0.029 13.7 0.1 0.046 13.1 0.1 1.3 1 0 0 1 1 1 0 Sea anemone cytotoxic protein OPT PF03169.10 EIW77662.1 - 2.7e-199 663.6 60.2 3.1e-199 663.4 41.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein p450 PF00067.17 EIW77664.1 - 2.1e-60 204.5 0.0 4.8e-60 203.3 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Hydantoinase_A PF01968.13 EIW77667.1 - 7.1e-92 307.5 0.0 1.2e-91 306.8 0.0 1.3 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EIW77667.1 - 3.7e-55 186.1 0.2 2.9e-52 176.7 0.0 2.4 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EIW77667.1 - 0.13 10.5 0.0 0.22 9.8 0.0 1.3 1 0 0 1 1 1 0 MutL protein HTH_Tnp_ISL3 PF13542.1 EIW77668.1 - 0.07 12.3 0.5 0.14 11.3 0.3 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DUF4419 PF14388.1 EIW77669.1 - 1.2e-60 205.2 0.0 1e-32 113.5 0.0 3.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4419) Pardaxin PF07425.6 EIW77669.1 - 0.73 9.2 7.6 0.74 9.2 3.2 2.5 2 1 0 2 2 2 0 Pardaxin Tricorn_C1 PF14684.1 EIW77671.1 - 0.039 13.8 0.0 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 Tricorn protease C1 domain G-alpha PF00503.15 EIW77671.1 - 0.11 11.1 0.0 0.33 9.5 0.0 1.7 2 0 0 2 2 2 0 G-protein alpha subunit RunxI PF08504.6 EIW77678.1 - 0.13 12.7 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Runx inhibition domain DUF2365 PF10157.4 EIW77679.1 - 0.054 13.3 0.2 0.36 10.7 0.0 2.3 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2365) Mito_fiss_reg PF05308.6 EIW77680.1 - 0.099 11.9 3.1 0.1 11.9 2.2 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 EIW77680.1 - 2.3 7.4 4.7 2.6 7.2 3.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DUF4419 PF14388.1 EIW77683.1 - 5e-42 144.1 0.0 6.6e-25 87.9 0.0 3.0 1 1 2 3 3 3 3 Domain of unknown function (DUF4419) Pardaxin PF07425.6 EIW77683.1 - 2.8 7.4 11.0 4.4 6.7 4.7 2.9 2 1 0 2 2 2 0 Pardaxin Sep15_SelM PF08806.6 EIW77684.1 - 0.13 12.0 0.1 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Sep15/SelM redox domain Miro PF08477.8 EIW77685.1 - 5.1e-07 30.2 0.0 2.4e-06 28.0 0.0 2.1 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIW77685.1 - 2.2e-05 24.4 0.0 5.1e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EIW77685.1 - 0.00083 18.1 0.0 0.49 9.0 0.0 2.6 3 0 0 3 3 3 2 G-protein alpha subunit Arf PF00025.16 EIW77685.1 - 0.001 18.3 0.1 0.0067 15.6 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_17 PF13207.1 EIW77685.1 - 0.0026 18.5 0.0 0.17 12.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.12 EIW77685.1 - 0.0068 15.9 0.2 0.89 9.0 0.1 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 EIW77685.1 - 0.007 16.0 0.1 0.058 13.0 0.0 2.2 1 1 1 2 2 2 1 Archaeal ATPase MobB PF03205.9 EIW77685.1 - 0.0082 15.8 0.0 0.018 14.7 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 EIW77685.1 - 0.0083 15.5 0.2 0.95 8.8 0.0 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EIW77685.1 - 0.034 13.6 0.0 0.15 11.5 0.0 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Tricorn_C1 PF14684.1 EIW77685.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Tricorn protease C1 domain FeoB_N PF02421.13 EIW77685.1 - 0.12 11.6 0.2 0.4 9.9 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B ATP-synt_ab PF00006.20 EIW77685.1 - 0.13 11.6 0.0 0.14 11.6 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 EIW77685.1 - 0.14 11.8 0.1 0.45 10.1 0.0 1.8 2 0 0 2 2 2 0 NTPase Polysacc_synt_2 PF02719.10 EIW77686.1 - 0.16 10.8 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SIT PF15330.1 EIW77687.1 - 1.2 9.3 4.0 0.45 10.6 0.1 2.2 2 1 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT Nop53 PF07767.6 EIW77687.1 - 4.9 6.0 39.6 0.072 12.0 11.8 2.7 1 1 1 2 2 2 0 Nop53 (60S ribosomal biogenesis) Polysacc_deac_1 PF01522.16 EIW77691.1 - 5.6e-29 100.2 0.0 9.2e-29 99.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF4419 PF14388.1 EIW77692.1 - 1.9e-97 326.1 0.0 2.3e-97 325.8 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) DUF3337 PF11816.3 EIW77695.1 - 9.2e-47 160.0 0.0 1e-45 156.5 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3337) WD40 PF00400.27 EIW77695.1 - 8.8e-32 107.8 16.6 1.4e-08 34.3 0.0 7.1 6 0 0 6 6 6 6 WD domain, G-beta repeat BAF1_ABF1 PF04684.8 EIW77695.1 - 1.6 7.4 13.9 2.5 6.8 9.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pyr_redox_3 PF13738.1 EIW77698.1 - 3e-21 76.4 0.0 1.7e-20 73.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW77698.1 - 6e-11 41.8 0.0 5.9e-08 32.0 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EIW77698.1 - 1.4e-10 41.0 0.2 5.8e-10 39.0 0.0 2.3 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EIW77698.1 - 3.3e-10 38.7 0.0 7.2e-10 37.6 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EIW77698.1 - 2e-06 27.8 0.0 0.022 14.6 0.0 3.2 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW77698.1 - 0.00018 20.6 0.2 0.001 18.2 0.0 2.3 3 0 0 3 3 3 1 Thi4 family DAO PF01266.19 EIW77698.1 - 0.001 18.0 0.0 0.013 14.4 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW77698.1 - 0.0044 15.9 0.0 0.0084 14.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EIW77698.1 - 0.01 15.6 0.2 0.12 12.1 0.0 2.8 3 1 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EIW77698.1 - 0.017 13.6 0.1 0.059 11.8 0.0 1.9 3 0 0 3 3 3 0 HI0933-like protein 2-Hacid_dh_C PF02826.14 EIW77698.1 - 0.068 12.3 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF1611 PF07755.6 EIW77698.1 - 0.1 11.2 0.0 0.56 8.7 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1611) Lycopene_cycl PF05834.7 EIW77698.1 - 0.11 11.4 0.0 0.21 10.4 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein MMR_HSR1 PF01926.18 EIW77699.1 - 7.7e-05 22.6 0.0 0.00017 21.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIW77699.1 - 0.0033 17.8 0.2 0.026 15.0 0.2 2.4 1 1 0 1 1 1 1 Miro-like protein AIG1 PF04548.11 EIW77699.1 - 0.0047 16.0 0.1 0.012 14.7 0.1 1.7 1 0 0 1 1 1 1 AIG1 family Septin PF00735.13 EIW77699.1 - 0.0056 15.7 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 Septin DUF258 PF03193.11 EIW77699.1 - 0.0068 15.6 0.0 0.038 13.1 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EIW77699.1 - 0.044 13.5 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Dynamin family DUF2422 PF10337.4 EIW77700.1 - 0.0032 16.3 0.0 0.0039 16.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2422) DUF4131 PF13567.1 EIW77700.1 - 0.01 15.2 0.0 0.013 14.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) MMR_HSR1 PF01926.18 EIW77701.1 - 2.5e-06 27.4 0.0 4.5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIW77701.1 - 0.00091 19.7 0.1 0.0035 17.8 0.1 2.0 1 1 0 1 1 1 1 Miro-like protein Septin PF00735.13 EIW77701.1 - 0.0016 17.4 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 Septin AIG1 PF04548.11 EIW77701.1 - 0.0051 15.9 0.0 0.0088 15.1 0.0 1.4 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EIW77701.1 - 0.025 13.7 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 T2SE PF00437.15 EIW77701.1 - 0.029 13.2 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Dynamin_N PF00350.18 EIW77701.1 - 0.04 13.7 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 Dynamin family ABC_tran PF00005.22 EIW77701.1 - 0.07 13.4 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF815 PF05673.8 EIW77701.1 - 0.079 11.8 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PSD3 PF07626.6 EIW77701.1 - 0.12 12.4 0.1 0.33 11.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1587) AAA_23 PF13476.1 EIW77701.1 - 0.12 12.6 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIW77701.1 - 0.14 11.7 0.1 0.31 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EIW77702.1 - 1.3e-05 25.1 0.0 3.7e-05 23.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIW77702.1 - 9.1e-05 22.9 0.0 0.00013 22.4 0.0 1.4 1 1 0 1 1 1 1 Miro-like protein Arch_ATPase PF01637.13 EIW77702.1 - 0.00043 20.0 0.0 0.00045 19.9 0.0 1.2 1 1 0 1 1 1 1 Archaeal ATPase MobB PF03205.9 EIW77702.1 - 0.00085 19.0 0.0 0.0021 17.7 0.0 1.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Arf PF00025.16 EIW77702.1 - 0.005 16.1 0.0 0.0063 15.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIW77702.1 - 0.01 15.2 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EIW77702.1 - 0.013 15.0 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.20 EIW77702.1 - 0.013 15.0 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 EIW77702.1 - 0.036 13.7 0.1 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_17 PF13207.1 EIW77702.1 - 0.065 14.0 0.1 0.077 13.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EIW77702.1 - 0.13 12.4 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EIW77702.1 - 0.13 12.1 0.1 0.17 11.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain DUF4419 PF14388.1 EIW77703.1 - 5.1e-31 108.0 0.0 7.2e-17 61.5 0.0 3.0 2 1 1 3 3 3 3 Domain of unknown function (DUF4419) Aa_trans PF01490.13 EIW77706.1 - 0.002 16.7 0.1 0.0028 16.2 0.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EIW77706.1 - 0.035 12.9 0.1 0.05 12.4 0.1 1.1 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family 7TM_GPCR_Srab PF10292.4 EIW77706.1 - 0.05 12.2 0.1 0.07 11.8 0.0 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor 6PF2K PF01591.13 EIW77707.1 - 4.9e-69 231.8 0.0 6.7e-69 231.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EIW77707.1 - 8.5e-33 113.6 0.0 2e-32 112.4 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EIW77707.1 - 6.8e-09 35.7 0.1 1.2e-08 34.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW77707.1 - 7.5e-05 23.5 0.1 0.00029 21.6 0.0 2.1 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EIW77707.1 - 0.0044 16.1 0.0 0.0082 15.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin GBP PF02263.14 EIW77707.1 - 0.042 12.8 0.0 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain KTI12 PF08433.5 EIW77707.1 - 0.073 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 HTH_WhiA PF02650.9 EIW77707.1 - 0.15 12.4 0.1 0.36 11.2 0.1 1.6 1 0 0 1 1 1 0 WhiA C-terminal HTH domain PIG-X PF08320.7 EIW77708.1 - 1.1e-21 77.1 0.0 1.4e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 PIG-X / PBN1 Ras PF00071.17 EIW77710.1 - 2.9e-53 179.5 0.0 3.3e-53 179.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW77710.1 - 1.8e-15 57.4 0.0 2.5e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW77710.1 - 2.2e-06 27.0 0.0 8e-06 25.2 0.0 1.7 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW77710.1 - 0.0021 17.2 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EIW77710.1 - 0.073 12.5 0.0 2.5 7.5 0.0 2.3 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EIW77710.1 - 0.15 11.7 0.0 0.2 11.3 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase adh_short PF00106.20 EIW77712.1 - 4.2e-27 95.1 10.0 5.4e-27 94.7 6.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW77712.1 - 2e-26 93.2 0.2 2.4e-26 92.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW77712.1 - 2.2e-07 30.7 5.8 3.1e-07 30.2 4.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW77712.1 - 0.0012 18.3 0.7 0.0053 16.2 0.5 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family HHH_5 PF14520.1 EIW77712.1 - 0.01 15.9 0.1 0.1 12.7 0.1 2.4 2 1 0 2 2 2 0 Helix-hairpin-helix domain 3Beta_HSD PF01073.14 EIW77712.1 - 0.012 14.3 0.8 0.016 13.9 0.5 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Acetyltransf_6 PF13480.1 EIW77712.1 - 0.056 13.3 1.8 0.14 12.0 1.2 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-C4H2 PF10146.4 EIW77713.1 - 0.00022 21.3 13.8 0.016 15.2 0.7 3.6 1 1 2 3 3 3 2 Zinc finger-containing protein ATG16 PF08614.6 EIW77713.1 - 0.00064 19.6 30.5 0.23 11.2 2.3 4.3 1 1 3 4 4 4 4 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.3 EIW77713.1 - 0.0007 19.3 16.5 0.081 12.7 0.0 5.8 4 1 2 6 6 6 2 TATA element modulatory factor 1 DNA binding GAS PF13851.1 EIW77713.1 - 0.0055 15.9 12.5 0.85 8.7 1.6 3.7 3 1 1 4 4 4 3 Growth-arrest specific micro-tubule binding CENP-Q PF13094.1 EIW77713.1 - 0.02 14.9 27.1 0.026 14.5 0.5 4.9 3 1 2 5 5 5 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4201 PF13870.1 EIW77713.1 - 0.064 12.6 13.8 0.36 10.2 0.9 4.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4201) Reo_sigmaC PF04582.7 EIW77713.1 - 0.17 11.0 18.6 0.031 13.4 3.1 3.3 2 1 1 3 3 3 0 Reovirus sigma C capsid protein FlaC_arch PF05377.6 EIW77713.1 - 0.32 10.9 14.8 9.8 6.1 0.1 5.5 6 0 0 6 6 6 0 Flagella accessory protein C (FlaC) ADIP PF11559.3 EIW77713.1 - 0.52 10.1 23.0 0.49 10.2 0.5 4.7 2 1 1 4 4 4 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.4 EIW77713.1 - 1.3 8.8 19.4 1.3 8.9 0.9 3.8 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Striatin PF08232.7 EIW77713.1 - 1.7 8.9 17.6 9.6 6.5 0.1 4.8 2 2 0 3 3 3 0 Striatin family TMCO5 PF14992.1 EIW77713.1 - 3.9 6.5 15.5 0.32 10.0 3.8 3.3 3 1 1 4 4 4 0 TMCO5 family Mnd1 PF03962.10 EIW77713.1 - 4.3 6.9 23.8 0.25 10.9 0.2 4.4 2 1 3 5 5 5 0 Mnd1 family Cortex-I_coil PF09304.5 EIW77713.1 - 8.6 6.4 21.2 0.044 13.8 3.1 3.8 2 1 0 3 3 3 0 Cortexillin I, coiled coil Gti1_Pac2 PF09729.4 EIW77714.1 - 9.2e-55 185.0 0.0 1.4e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 Gti1/Pac2 family WXG100 PF06013.7 EIW77715.1 - 0.0064 16.4 2.5 0.32 11.0 0.0 3.3 2 1 1 3 3 3 1 Proteins of 100 residues with WXG DUF2203 PF09969.4 EIW77715.1 - 0.12 12.6 3.3 0.63 10.2 0.1 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) Snapin_Pallidin PF14712.1 EIW77715.1 - 1.2 9.5 4.2 15 5.9 0.0 3.5 4 1 0 4 4 4 0 Snapin/Pallidin HAUS6_N PF14661.1 EIW77715.1 - 1.3 8.3 15.8 1.3 8.2 2.4 2.3 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Mnd1 PF03962.10 EIW77715.1 - 2.9 7.5 18.6 0.45 10.1 2.8 3.2 1 1 2 3 3 3 0 Mnd1 family DUF3752 PF12572.3 EIW77715.1 - 4.5 7.3 10.0 0.88 9.6 2.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF3752) DMPK_coil PF08826.5 EIW77715.1 - 7.8 6.4 17.2 0.21 11.4 0.3 4.1 5 0 0 5 5 5 0 DMPK coiled coil domain like Prefoldin PF02996.12 EIW77716.1 - 2.6e-31 107.7 1.8 4.1e-31 107.1 1.2 1.3 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 EIW77716.1 - 2.4e-06 27.2 0.1 6.5e-06 25.8 0.1 1.8 1 1 0 1 1 1 1 Prefoldin subunit Transcrip_act PF04949.8 EIW77716.1 - 0.00041 20.0 0.9 0.039 13.5 0.2 2.1 2 0 0 2 2 2 1 Transcriptional activator Prefoldin_2 PF01920.15 EIW77716.1 - 0.00078 19.1 8.2 0.0047 16.6 0.2 2.4 2 1 0 2 2 2 1 Prefoldin subunit COG2 PF06148.6 EIW77716.1 - 0.0057 16.5 1.1 0.31 10.9 0.1 2.1 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 TACC PF05010.9 EIW77716.1 - 0.012 15.4 1.2 0.018 14.8 0.8 1.3 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Cep57_MT_bd PF06657.8 EIW77716.1 - 0.015 15.1 1.6 0.05 13.5 0.3 2.1 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF1664 PF07889.7 EIW77716.1 - 0.021 14.5 5.5 0.77 9.5 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF745 PF05335.8 EIW77716.1 - 0.025 14.1 3.3 0.88 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF4407 PF14362.1 EIW77716.1 - 0.036 13.0 4.3 0.047 12.6 3.0 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) ADIP PF11559.3 EIW77716.1 - 0.036 13.9 6.3 0.96 9.3 2.2 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding UPF0449 PF15136.1 EIW77716.1 - 0.043 14.0 4.3 0.76 10.0 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 GAS PF13851.1 EIW77716.1 - 0.043 13.0 7.6 0.076 12.2 1.4 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EIW77716.1 - 0.054 13.3 4.5 0.18 11.6 0.9 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DASH_Dad2 PF08654.5 EIW77716.1 - 0.055 13.4 1.6 2.1 8.3 0.1 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad2 V_ATPase_I PF01496.14 EIW77716.1 - 0.071 10.9 1.2 0.097 10.5 0.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF1409 PF07197.7 EIW77716.1 - 0.074 13.1 0.9 0.23 11.5 0.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1409) Barstar PF01337.13 EIW77716.1 - 0.082 12.7 0.1 9.9 6.0 0.0 2.2 2 0 0 2 2 2 0 Barstar (barnase inhibitor) AIP3 PF03915.8 EIW77716.1 - 0.098 11.5 3.4 0.17 10.7 2.4 1.4 1 1 0 1 1 1 0 Actin interacting protein 3 Baculo_PEP_C PF04513.7 EIW77716.1 - 0.11 12.3 9.3 1.3 8.8 0.4 2.2 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus IncA PF04156.9 EIW77716.1 - 0.15 11.6 5.9 2.4 7.6 2.9 2.1 2 0 0 2 2 2 0 IncA protein Apolipoprotein PF01442.13 EIW77716.1 - 0.24 10.8 5.5 6 6.3 1.3 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Filament PF00038.16 EIW77716.1 - 0.25 10.7 8.4 0.7 9.3 0.7 2.0 1 1 1 2 2 2 0 Intermediate filament protein DUF4164 PF13747.1 EIW77716.1 - 0.37 10.9 2.7 7.9 6.6 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Seryl_tRNA_N PF02403.17 EIW77716.1 - 0.43 10.6 6.8 4.1 7.4 0.4 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GCN5L1 PF06320.8 EIW77716.1 - 0.44 10.3 3.5 1.7 8.4 0.5 2.1 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) bZIP_1 PF00170.16 EIW77716.1 - 0.62 10.0 2.8 1.5 8.8 0.3 2.1 2 0 0 2 2 2 0 bZIP transcription factor WXG100 PF06013.7 EIW77716.1 - 0.65 10.0 5.6 9.4 6.3 0.3 2.5 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Fib_alpha PF08702.5 EIW77716.1 - 0.68 10.0 6.9 6 6.9 0.5 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family V-SNARE PF05008.10 EIW77716.1 - 0.79 9.9 10.2 0.53 10.4 1.9 2.5 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Spc7 PF08317.6 EIW77716.1 - 1.2 7.7 7.6 0.52 8.9 1.1 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein TMPIT PF07851.8 EIW77716.1 - 1.2 8.1 5.7 1.1 8.3 0.2 2.1 2 0 0 2 2 2 0 TMPIT-like protein IFP_35_N PF07334.8 EIW77716.1 - 1.3 9.0 5.3 1.3 9.0 0.6 2.3 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Fzo_mitofusin PF04799.8 EIW77716.1 - 1.9 7.8 6.2 5.1 6.4 2.0 2.1 2 0 0 2 2 2 0 fzo-like conserved region Atg14 PF10186.4 EIW77716.1 - 2 7.2 8.7 4.4 6.1 0.4 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 RasGAP_C PF03836.10 EIW77716.1 - 3.5 7.3 9.8 2.4 7.8 0.9 2.2 2 0 0 2 2 2 0 RasGAP C-terminus LPP PF04728.8 EIW77716.1 - 3.5 7.4 8.0 5 7.0 1.8 2.6 2 1 0 2 2 2 0 Lipoprotein leucine-zipper NPV_P10 PF05531.7 EIW77716.1 - 3.6 7.9 6.7 2.8 8.2 0.3 2.5 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TMF_DNA_bd PF12329.3 EIW77716.1 - 3.6 7.4 7.7 4.1 7.2 0.5 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.4 EIW77716.1 - 4.3 7.5 8.8 2.4 8.3 0.4 2.6 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlxA PF14282.1 EIW77716.1 - 4.4 7.3 19.8 0.8 9.6 1.2 2.1 2 0 0 2 2 2 0 FlxA-like protein Cortex-I_coil PF09304.5 EIW77716.1 - 6.1 6.9 8.1 21 5.1 0.3 2.6 2 1 0 2 2 2 0 Cortexillin I, coiled coil DUF2347 PF09804.4 EIW77717.1 - 7.2e-45 153.4 0.0 1.4e-44 152.4 0.0 1.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) Avl9 PF09794.4 EIW77717.1 - 0.00075 18.0 0.1 1.3 7.4 0.1 3.1 2 1 0 3 3 3 3 Transport protein Avl9 SPA PF08616.5 EIW77717.1 - 0.022 14.4 0.0 0.09 12.4 0.0 1.8 2 0 0 2 2 2 0 Stabilization of polarity axis PIN_4 PF13638.1 EIW77718.1 - 9.9e-07 28.9 0.0 1.5e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 PIN domain PI-PLC-X PF00388.14 EIW77727.1 - 4.6e-40 136.3 0.0 1e-39 135.2 0.0 1.6 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EIW77727.1 - 1.5e-24 86.2 0.0 2.4e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain MAGE PF01454.14 EIW77728.1 - 1.2e-33 116.1 0.0 3.5e-31 108.0 0.0 2.1 2 0 0 2 2 2 2 MAGE family Sugar_tr PF00083.19 EIW77729.1 - 9.6e-121 403.4 32.0 1.1e-120 403.3 22.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW77729.1 - 4e-20 71.8 43.6 2.1e-14 53.0 13.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW77731.1 - 1.1e-20 73.7 5.3 3.4e-20 72.0 3.7 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter 7TM-7TMR_HD PF07698.6 EIW77731.1 - 0.00052 19.5 2.3 0.00079 18.9 1.6 1.4 1 0 0 1 1 1 1 7TM receptor with intracellular HD hydrolase Herpes_pp38 PF04846.8 EIW77731.1 - 0.0045 16.2 0.0 0.0086 15.3 0.0 1.5 1 0 0 1 1 1 1 Herpesvirus pp38 phosphoprotein DUF2484 PF10658.4 EIW77731.1 - 1.6 8.9 7.5 5.8 7.1 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2484) ATP_bind_1 PF03029.12 EIW77732.1 - 3.1e-78 262.6 0.0 4.5e-78 262.0 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EIW77732.1 - 0.00011 21.6 0.0 0.00072 19.0 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EIW77732.1 - 0.00058 19.7 0.0 0.0015 18.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EIW77732.1 - 0.0021 17.9 0.1 0.0063 16.4 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EIW77732.1 - 0.0054 15.4 0.0 0.39 9.3 0.0 2.4 2 0 0 2 2 2 1 G-protein alpha subunit ArgK PF03308.11 EIW77732.1 - 0.0067 15.2 0.0 1.7 7.3 0.0 2.3 2 0 0 2 2 2 2 ArgK protein AAA_17 PF13207.1 EIW77732.1 - 0.0082 16.9 2.1 0.016 16.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain FeoB_N PF02421.13 EIW77732.1 - 0.0089 15.3 0.1 0.043 13.1 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_22 PF13401.1 EIW77732.1 - 0.013 15.6 0.0 0.037 14.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIW77732.1 - 0.014 14.5 0.1 0.035 13.2 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin CbiA PF01656.18 EIW77732.1 - 0.015 14.6 0.4 0.07 12.5 0.3 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.7 EIW77732.1 - 0.017 14.8 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 EIW77732.1 - 0.023 14.1 0.2 0.45 9.9 0.1 2.3 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 EIW77732.1 - 0.025 14.5 0.0 0.13 12.1 0.0 2.2 2 1 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.1 EIW77732.1 - 0.025 14.1 0.1 0.051 13.1 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIW77732.1 - 0.032 13.4 0.0 0.26 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 SRP54 PF00448.17 EIW77732.1 - 0.032 13.6 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain PAPA-1 PF04795.7 EIW77732.1 - 0.033 14.9 3.2 0.071 13.8 2.2 1.5 1 0 0 1 1 1 0 PAPA-1-like conserved region NTPase_1 PF03266.10 EIW77732.1 - 0.049 13.3 0.0 1.2 8.7 0.0 2.2 2 0 0 2 2 2 0 NTPase KAP_NTPase PF07693.9 EIW77732.1 - 0.084 11.8 0.0 0.12 11.3 0.0 1.4 1 1 0 1 1 1 0 KAP family P-loop domain NB-ARC PF00931.17 EIW77732.1 - 0.088 11.6 0.0 0.21 10.4 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain UPF0079 PF02367.12 EIW77732.1 - 0.099 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Pkinase PF00069.20 EIW77733.1 - 1.8e-72 243.6 0.0 2e-72 243.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW77733.1 - 2.7e-33 115.1 0.0 3.4e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW77733.1 - 0.0078 15.9 0.2 0.016 14.9 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EIW77733.1 - 0.044 13.1 0.0 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kinase-like PF14531.1 EIW77733.1 - 0.082 11.8 0.0 0.21 10.5 0.0 1.6 1 1 0 2 2 2 0 Kinase-like Kdo PF06293.9 EIW77733.1 - 0.086 11.8 0.1 0.24 10.4 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EIW77733.1 - 0.11 11.3 0.0 0.3 9.8 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 FHA PF00498.21 EIW77734.1 - 3.4e-08 33.4 0.1 8.1e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 FHA domain Baculo_PEP_C PF04513.7 EIW77734.1 - 0.00015 21.6 1.8 0.022 14.6 0.0 2.3 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus NPV_P10 PF05531.7 EIW77734.1 - 0.00034 20.8 4.6 0.017 15.3 0.1 3.3 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein FUSC PF04632.7 EIW77734.1 - 0.0016 16.9 8.9 0.0035 15.8 6.1 1.6 1 0 0 1 1 1 1 Fusaric acid resistance protein family Syntaxin-6_N PF09177.6 EIW77734.1 - 0.0022 18.3 7.2 0.72 10.3 1.0 2.8 1 1 0 2 2 2 2 Syntaxin 6, N-terminal Herpes_U30 PF04523.8 EIW77734.1 - 0.016 12.7 4.2 0.16 9.3 0.5 2.1 1 1 1 2 2 2 0 Herpes virus tegument protein U30 Laminin_II PF06009.7 EIW77734.1 - 0.018 14.7 4.3 0.026 14.2 0.1 2.4 1 1 2 3 3 3 0 Laminin Domain II COG5 PF10392.4 EIW77734.1 - 0.019 14.9 2.4 0.4 10.6 0.1 2.5 2 0 0 2 2 2 0 Golgi transport complex subunit 5 DUF948 PF06103.6 EIW77734.1 - 0.053 13.3 3.6 1 9.2 0.0 3.2 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 EIW77734.1 - 0.075 12.2 5.7 0.2 10.7 0.7 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein SPT16 PF08644.6 EIW77734.1 - 0.092 12.5 1.0 0.2 11.4 0.7 1.6 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) FliD_N PF02465.13 EIW77734.1 - 0.098 13.0 8.9 0.45 10.9 0.4 4.0 3 1 1 4 4 3 0 Flagellar hook-associated protein 2 N-terminus Pex14_N PF04695.8 EIW77734.1 - 0.13 12.3 3.1 1 9.3 0.1 3.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4559 PF15112.1 EIW77734.1 - 0.15 11.2 5.9 0.21 10.6 4.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) RmuC PF02646.11 EIW77734.1 - 0.16 10.7 3.8 0.31 9.8 0.0 2.2 2 0 0 2 2 2 0 RmuC family Spc7 PF08317.6 EIW77734.1 - 0.28 9.7 7.5 0.6 8.7 4.1 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein HisKA PF00512.20 EIW77734.1 - 0.62 10.0 4.9 0.3 11.1 0.3 2.8 2 1 1 3 3 3 0 His Kinase A (phospho-acceptor) domain DUF1664 PF07889.7 EIW77734.1 - 0.76 9.5 4.3 9 6.1 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Syntaxin PF00804.20 EIW77734.1 - 0.87 9.7 5.4 17 5.6 3.4 2.7 1 1 0 1 1 1 0 Syntaxin TBPIP PF07106.8 EIW77734.1 - 1.3 8.5 8.1 13 5.3 0.1 2.3 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Atg14 PF10186.4 EIW77734.1 - 3.5 6.4 7.0 6.6 5.5 0.0 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Tim54 PF11711.3 EIW77734.1 - 6.8 5.1 11.3 0.92 8.0 2.6 2.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Adeno_PIX PF03955.9 EIW77734.1 - 8.7 6.9 8.2 19 5.8 0.1 3.6 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) DUF2762 PF10960.3 EIW77735.1 - 0.51 10.0 2.5 1.1 9.0 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2762) SAC3_GANP PF03399.11 EIW77736.1 - 7.5e-22 77.8 0.0 1.2e-21 77.2 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family TBX PF12598.3 EIW77738.1 - 0.085 13.2 1.6 0.2 12.0 1.1 1.6 1 0 0 1 1 1 0 T-box transcription factor Glyco_hydro_16 PF00722.16 EIW77739.1 - 6.9e-19 67.8 0.1 3.4e-18 65.6 0.0 2.1 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 B-block_TFIIIC PF04182.7 EIW77740.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.3 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Glyco_trans_2_3 PF13632.1 EIW77741.1 - 1.2e-51 175.2 0.3 1.2e-51 175.2 0.2 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIW77741.1 - 4.2e-11 43.0 0.3 1.8e-10 41.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EIW77741.1 - 0.0013 18.4 0.0 0.0053 16.4 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIW77741.1 - 0.013 14.7 0.0 0.042 13.1 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferase family 21 DUF2101 PF09874.4 EIW77741.1 - 0.43 10.0 2.9 1.1 8.6 2.0 1.6 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) Glyco_trans_2_3 PF13632.1 EIW77742.1 - 3.9e-50 170.2 0.4 3.9e-50 170.2 0.2 2.4 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIW77742.1 - 1.5e-11 44.5 0.6 6e-11 42.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EIW77742.1 - 0.0013 18.4 0.2 0.0051 16.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIW77742.1 - 0.0072 15.6 0.0 0.022 14.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 21 MMR_HSR1 PF01926.18 EIW77743.1 - 4.6e-20 71.7 0.4 1.4e-15 57.2 0.1 2.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EIW77743.1 - 1e-07 31.4 0.1 2.9e-06 26.6 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EIW77743.1 - 6.6e-06 25.6 0.0 0.0029 17.0 0.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EIW77743.1 - 0.00012 21.2 0.1 0.00023 20.3 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EIW77743.1 - 0.00034 20.4 2.7 0.36 10.6 1.0 3.0 2 1 0 2 2 2 2 Dynamin family Miro PF08477.8 EIW77743.1 - 0.0014 19.1 0.2 0.44 11.0 0.1 2.7 2 1 0 2 2 2 1 Miro-like protein ArgK PF03308.11 EIW77743.1 - 0.0056 15.5 0.2 0.02 13.6 0.0 1.9 1 1 1 2 2 2 1 ArgK protein AIG1 PF04548.11 EIW77743.1 - 0.0066 15.5 0.5 0.021 13.9 0.1 1.9 2 0 0 2 2 2 1 AIG1 family Arf PF00025.16 EIW77743.1 - 0.011 14.9 0.1 2.8 7.1 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.14 EIW77743.1 - 0.014 14.8 0.1 1.1 8.7 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TIR_2 PF13676.1 EIW77743.1 - 0.032 14.3 0.1 0.06 13.4 0.1 1.4 1 0 0 1 1 1 0 TIR domain THF_DHG_CYH_C PF02882.14 EIW77743.1 - 0.046 12.7 0.2 0.16 11.0 0.0 1.8 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PduV-EutP PF10662.4 EIW77743.1 - 0.046 13.1 0.0 3.4 7.1 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EIW77743.1 - 0.052 13.5 0.6 2.4 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 EIW77743.1 - 0.078 12.6 0.1 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B 2-Hacid_dh_C PF02826.14 EIW77743.1 - 0.12 11.5 0.0 6.6 5.8 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AAA_18 PF13238.1 EIW77743.1 - 0.13 12.5 1.0 0.34 11.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EIW77743.1 - 0.14 12.9 0.8 2.9 8.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EIW77745.1 - 2.3e-05 24.2 0.0 3.2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 EIW77745.1 - 0.00056 19.6 0.1 0.0011 18.6 0.1 1.5 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EIW77745.1 - 0.0008 19.8 0.0 0.0011 19.4 0.0 1.3 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW77745.1 - 0.0015 17.7 0.0 0.0021 17.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 EIW77745.1 - 0.042 13.3 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_17 PF13207.1 EIW77745.1 - 0.042 14.6 0.2 0.054 14.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain TMEM240 PF15207.1 EIW77745.1 - 0.091 12.3 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 TMEM240 family FeoB_N PF02421.13 EIW77745.1 - 0.1 11.8 0.0 0.22 10.8 0.0 1.5 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_22 PF13401.1 EIW77745.1 - 0.12 12.5 0.0 0.15 12.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain Ion_trans PF00520.26 EIW77746.1 - 2.3e-98 327.3 94.3 3e-31 108.2 11.5 5.7 7 0 0 7 7 7 4 Ion transport protein HET PF06985.6 EIW77747.1 - 7.7e-19 68.2 0.2 2.5e-16 60.0 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Sirohm_synth_C PF14823.1 EIW77747.1 - 0.011 15.0 0.0 0.031 13.5 0.0 1.7 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal Glyco_trans_2_3 PF13632.1 EIW77747.1 - 0.067 12.8 1.4 0.077 12.6 0.2 1.5 2 0 0 2 2 2 0 Glycosyl transferase family group 2 GIDA PF01134.17 EIW77749.1 - 8.3e-155 515.4 0.0 1e-154 515.1 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EIW77749.1 - 7.8e-17 61.1 0.0 4e-16 58.8 0.0 2.2 2 0 0 2 2 2 1 GidA associated domain 3 FAD_oxidored PF12831.2 EIW77749.1 - 7.5e-07 28.5 2.4 2.8e-06 26.6 1.8 1.8 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIW77749.1 - 2.8e-06 27.3 0.4 9.4e-06 25.6 0.3 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW77749.1 - 8.1e-05 21.6 3.8 0.092 11.6 0.3 3.2 3 1 1 4 4 4 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW77749.1 - 0.00068 18.6 0.8 0.0019 17.1 0.5 1.8 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EIW77749.1 - 0.0069 16.7 0.2 0.018 15.4 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW77749.1 - 0.017 13.6 3.1 0.26 9.7 0.2 2.6 3 0 0 3 3 3 0 HI0933-like protein AlaDh_PNT_C PF01262.16 EIW77749.1 - 0.14 11.7 0.1 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain p450 PF00067.17 EIW77750.1 - 4e-59 200.3 0.0 6.7e-59 199.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C12 PF01088.16 EIW77752.1 - 1.3e-57 194.4 0.0 1.7e-57 194.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Oxidored_FMN PF00724.15 EIW77753.1 - 4.6e-50 170.5 0.0 6e-50 170.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TolB_N PF04052.8 EIW77753.1 - 0.092 12.8 0.0 0.31 11.1 0.0 1.8 2 0 0 2 2 2 0 TolB amino-terminal domain HMGL-like PF00682.14 EIW77753.1 - 0.13 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 HMGL-like Kdo PF06293.9 EIW77754.1 - 5.4e-10 38.6 0.0 1.1e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EIW77754.1 - 3.9e-07 29.4 0.2 1.4e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 EIW77754.1 - 1.4e-06 28.2 0.2 1.2e-05 25.1 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EIW77754.1 - 4.9e-05 22.6 0.0 6.2e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase RIO1 PF01163.17 EIW77754.1 - 7.8e-05 22.1 0.0 0.0027 17.0 0.1 2.2 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 EIW77754.1 - 0.007 15.9 0.0 0.011 15.2 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase_Tyr PF07714.12 EIW77754.1 - 0.0082 15.2 0.2 0.019 14.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase PI3_PI4_kinase PF00454.22 EIW77754.1 - 0.033 13.6 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase WaaY PF06176.6 EIW77754.1 - 0.039 13.1 0.0 0.057 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Glyco_hydro_47 PF01532.15 EIW77755.1 - 7.8e-110 367.6 2.2 8.9e-110 367.4 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1832 PF08870.6 EIW77755.1 - 0.18 11.5 0.0 0.59 9.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1832) Epimerase PF01370.16 EIW77756.1 - 1.6e-20 73.5 0.0 2.1e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW77756.1 - 2e-15 57.2 0.0 2.5e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIW77756.1 - 4.6e-08 32.1 0.0 5.9e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EIW77756.1 - 2.3e-05 23.4 0.0 3.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 EIW77756.1 - 3.6e-05 23.1 0.0 4.8e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 EIW77756.1 - 0.00053 19.0 0.0 0.0007 18.6 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 EIW77756.1 - 0.0014 18.6 0.4 0.0024 17.7 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase TrkA_N PF02254.13 EIW77756.1 - 0.0015 18.5 0.1 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain DapB_N PF01113.15 EIW77756.1 - 0.015 15.1 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 EIW77756.1 - 0.069 12.0 0.1 0.16 10.8 0.0 1.6 2 0 0 2 2 2 0 Male sterility protein SEP PF08059.8 EIW77757.1 - 1.3e-24 86.2 0.0 2.5e-24 85.3 0.0 1.5 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 EIW77757.1 - 2.2e-15 56.4 0.0 3.6e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 UBX domain Spt20 PF12090.3 EIW77757.1 - 0.054 12.8 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Spt20 family Herpes_capsid PF06112.6 EIW77757.1 - 7.9 6.5 6.9 22 5.0 4.8 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein ENTH PF01417.15 EIW77758.1 - 2e-51 173.0 0.1 3.7e-51 172.1 0.0 1.5 1 0 0 1 1 1 1 ENTH domain ENTH PF01417.15 EIW77759.1 - 5.1e-49 165.2 0.1 7.4e-49 164.7 0.1 1.2 1 0 0 1 1 1 1 ENTH domain UIM PF02809.15 EIW77759.1 - 2e-05 23.7 3.0 0.00096 18.5 0.3 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif ANTH PF07651.11 EIW77759.1 - 6.9e-05 21.6 0.0 0.00012 20.9 0.0 1.3 1 0 0 1 1 1 1 ANTH domain F-box-like PF12937.2 EIW77763.1 - 0.01 15.5 0.1 0.029 14.0 0.0 1.8 1 0 0 1 1 1 0 F-box-like DUF1690 PF07956.6 EIW77764.1 - 8e-15 55.0 3.9 6.6e-12 45.5 2.7 2.1 1 1 0 1 1 1 1 Protein of Unknown function (DUF1690) DUF3022 PF11226.3 EIW77764.1 - 0.34 10.8 2.6 0.22 11.4 0.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3022) Herpes_UL25 PF01499.11 EIW77764.1 - 5.3 5.2 6.9 4.6 5.4 4.0 1.3 1 1 0 1 1 1 0 Herpesvirus UL25 family Peptidase_M24 PF00557.19 EIW77765.1 - 9.5e-56 188.6 0.0 1.3e-55 188.2 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EIW77765.1 - 5.2e-16 58.2 0.0 9.3e-16 57.4 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain RNase_PH PF01138.16 EIW77766.1 - 2.3e-17 63.5 0.0 4.5e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 MAD PF05557.8 EIW77767.1 - 0.011 13.9 0.2 0.013 13.6 0.2 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Cellulase PF00150.13 EIW77768.1 - 3.2e-33 115.1 1.0 5.1e-33 114.4 0.7 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AP_endonuc_2 PF01261.19 EIW77768.1 - 0.0077 15.5 0.0 0.016 14.4 0.0 1.6 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Radical_SAM PF04055.16 EIW77768.1 - 0.043 13.9 0.0 0.24 11.5 0.0 2.2 3 0 0 3 3 3 0 Radical SAM superfamily CBF PF03914.12 EIW77769.1 - 1.6e-31 109.0 0.1 1.3e-30 106.0 0.0 2.5 2 0 0 2 2 2 1 CBF/Mak21 family Saccharop_dh PF03435.13 EIW77770.1 - 3.8e-77 259.8 0.0 5.1e-77 259.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase AlaDh_PNT_N PF05222.10 EIW77770.1 - 4.8e-11 42.7 0.0 1.5e-10 41.2 0.0 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EIW77770.1 - 7.7e-09 35.3 0.0 4.8e-08 32.7 0.0 2.2 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 EIW77770.1 - 2.1e-05 24.6 0.1 4e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 EIW77770.1 - 0.0053 17.0 0.1 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain EVC2_like PF12297.3 EIW77770.1 - 0.038 12.6 0.0 0.066 11.8 0.0 1.3 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein NAD_binding_7 PF13241.1 EIW77770.1 - 0.046 13.9 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Stanniocalcin PF03298.8 EIW77770.1 - 0.22 10.5 0.0 0.4 9.6 0.0 1.3 1 0 0 1 1 1 0 Stanniocalcin family HSP70 PF00012.15 EIW77771.1 - 0.042 11.7 0.0 0.059 11.2 0.0 1.2 1 0 0 1 1 1 0 Hsp70 protein WD40 PF00400.27 EIW77774.1 - 4e-06 26.4 0.2 4e-06 26.4 0.1 3.7 5 0 0 5 5 5 1 WD domain, G-beta repeat FAD_binding_3 PF01494.14 EIW77775.1 - 0.013 14.5 0.2 0.02 13.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Thioredoxin_9 PF14595.1 EIW77775.1 - 0.033 13.7 0.0 0.048 13.2 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Asp PF00026.18 EIW77777.1 - 1.7e-19 70.2 0.5 1.8e-18 66.8 0.4 1.9 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Sad1_UNC PF07738.8 EIW77778.1 - 6.2e-17 61.6 0.0 4.4e-09 36.2 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal MRJP PF03022.11 EIW77778.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Major royal jelly protein Med9 PF07544.8 EIW77779.1 - 0.37 10.5 12.4 0.52 10.0 0.3 4.3 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 CorA PF01544.13 EIW77779.1 - 4.7 6.1 15.4 1.2 8.1 4.1 2.4 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein NPV_P10 PF05531.7 EIW77779.1 - 6.3 7.1 10.9 33 4.8 1.5 4.1 1 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein XhlA PF10779.4 EIW77779.1 - 8.1 6.4 12.5 8.1 6.4 0.9 3.7 2 1 1 3 3 3 0 Haemolysin XhlA Spc7 PF08317.6 EIW77779.1 - 8.6 4.9 15.4 3.2 6.3 1.3 2.5 1 1 2 3 3 3 0 Spc7 kinetochore protein BTB PF00651.26 EIW77783.1 - 3.4e-10 39.8 0.0 1e-09 38.3 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Pkinase PF00069.20 EIW77784.1 - 1.6e-62 211.0 0.0 2.1e-62 210.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW77784.1 - 1.3e-33 116.1 0.1 7.7e-33 113.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EIW77784.1 - 2.1e-15 56.5 0.2 4e-15 55.6 0.2 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EIW77784.1 - 1.4e-06 27.4 0.0 1.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIW77784.1 - 4.7e-06 25.8 0.0 7.5e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW77784.1 - 0.0032 17.2 0.0 0.02 14.6 0.0 2.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family RAP1 PF07218.6 EIW77784.1 - 0.0084 14.2 0.3 0.012 13.7 0.2 1.1 1 0 0 1 1 1 1 Rhoptry-associated protein 1 (RAP-1) RIO1 PF01163.17 EIW77784.1 - 0.014 14.7 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family BRO1 PF03097.13 EIW77785.1 - 2.3e-96 322.8 0.2 7.5e-96 321.1 0.0 1.8 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EIW77785.1 - 9.2e-22 77.3 0.2 1.7e-21 76.4 0.1 1.4 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV RRF PF01765.14 EIW77785.1 - 0.059 12.8 0.1 0.16 11.4 0.1 1.7 1 0 0 1 1 1 0 Ribosome recycling factor MOR2-PAG1_N PF14222.1 EIW77787.1 - 3.3e-06 26.0 0.1 3.8e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Cell morphogenesis N-terminal Cauli_VI PF01693.11 EIW77791.1 - 3.5e-07 30.1 0.0 5.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin Pex14_N PF04695.8 EIW77791.1 - 1.7 8.7 8.0 0.31 11.0 0.2 2.4 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF21 PF01595.15 EIW77793.1 - 1.4e-30 105.9 2.8 2.4e-30 105.1 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EIW77793.1 - 0.00064 19.4 0.4 2.4 8.0 0.0 3.4 3 0 0 3 3 3 2 CBS domain ABC1 PF03109.11 EIW77794.1 - 9.8e-29 99.7 0.5 1.8e-28 98.9 0.3 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EIW77794.1 - 0.00028 20.7 0.1 0.0012 18.6 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Mid1 PF12929.2 EIW77795.1 - 1.5e-67 228.2 0.4 2e-67 227.7 0.2 1.1 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component Fz PF01392.17 EIW77795.1 - 0.012 16.0 1.7 0.37 11.1 0.1 2.3 2 0 0 2 2 2 0 Fz domain tRNA-synt_1 PF00133.17 EIW77796.1 - 1.9e-208 693.2 0.0 1.6e-207 690.2 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EIW77796.1 - 1.6e-37 128.5 0.2 3.2e-37 127.6 0.1 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EIW77796.1 - 1e-13 50.7 0.0 5e-07 28.7 0.0 4.2 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EIW77796.1 - 5.4e-12 45.4 0.1 6.7e-08 32.0 0.0 2.5 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EIW77796.1 - 0.029 13.4 0.0 0.6 9.1 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Val_tRNA-synt_C PF10458.4 EIW77796.1 - 0.082 13.0 9.0 0.41 10.7 1.3 3.4 3 0 0 3 3 3 0 Valyl tRNA synthetase tRNA binding arm DDE_3 PF13358.1 EIW77797.1 - 7.6e-09 35.4 0.0 1.2e-05 25.1 0.0 2.7 2 1 0 2 2 2 2 DDE superfamily endonuclease Misat_Tub_SegII PF10644.4 EIW77797.1 - 0.079 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain DDE_Tnp_4 PF13359.1 EIW77798.1 - 5.8e-20 71.4 0.0 8.2e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Retrotrans_gag PF03732.12 EIW77801.1 - 2.9e-09 36.8 2.1 6.1e-09 35.8 1.2 1.8 1 1 0 1 1 1 1 Retrotransposon gag protein Ribosomal_60s PF00428.14 EIW77803.1 - 2.8 8.3 8.9 1 9.7 3.8 2.1 1 1 1 2 2 2 0 60s Acidic ribosomal protein Tet_JBP PF12851.2 EIW77805.1 - 0.0063 15.8 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily DDE_1 PF03184.14 EIW77811.1 - 0.0087 15.2 0.0 0.0091 15.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIW77812.1 - 0.0013 17.9 0.0 0.0014 17.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease CAP59_mtransfer PF11735.3 EIW77813.1 - 1.1e-43 149.2 0.0 1.7e-43 148.6 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 JmjC PF02373.17 EIW77815.1 - 5.9e-36 123.1 0.1 1.1e-35 122.3 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.12 EIW77815.1 - 1.8e-16 59.3 0.2 4.1e-16 58.2 0.2 1.7 1 0 0 1 1 1 1 jmjN domain zf-HC5HC2H PF13771.1 EIW77815.1 - 1.3e-11 44.5 1.1 2.7e-11 43.4 0.4 1.9 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EIW77815.1 - 1.7e-10 40.8 0.2 1.7e-10 40.8 0.1 2.0 2 0 0 2 2 2 1 PHD-zinc-finger like domain PHD PF00628.24 EIW77815.1 - 0.008 15.8 2.5 0.03 14.0 1.8 2.0 1 0 0 1 1 1 1 PHD-finger DUF966 PF06136.8 EIW77815.1 - 9.7 5.4 13.9 0.38 10.1 3.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF966) OTCace_N PF02729.16 EIW77816.1 - 1.2e-44 151.3 0.0 1.7e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EIW77816.1 - 1.4e-39 135.4 0.0 2e-39 135.0 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OCD_Mu_crystall PF02423.10 EIW77816.1 - 0.021 13.6 0.1 0.031 13.0 0.1 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family HMG_box_2 PF09011.5 EIW77817.1 - 2.5e-08 34.1 0.1 2.5e-08 34.1 0.1 1.7 2 0 0 2 2 2 1 HMG-box domain HMG_box PF00505.14 EIW77817.1 - 0.00049 20.3 0.2 0.00049 20.3 0.1 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box IFT46_B_C PF12317.3 EIW77818.1 - 0.28 10.4 3.1 0.76 9.0 0.0 2.9 3 0 0 3 3 3 0 Intraflagellar transport complex B protein 46 C terminal OTCace_N PF02729.16 EIW77819.1 - 5.5e-17 61.7 0.0 8.3e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DUF92 PF01940.11 EIW77820.1 - 2.4e-54 183.8 4.2 3.1e-54 183.5 2.9 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 DUF937 PF06078.6 EIW77820.1 - 0.036 14.2 0.9 0.073 13.2 0.6 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF937) Glycogen_syn PF05693.8 EIW77821.1 - 0 1077.3 0.0 0 1077.0 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glyco_transf_5 PF08323.6 EIW77821.1 - 4.3e-08 32.9 0.4 1.2e-07 31.4 0.1 1.9 2 1 1 3 3 3 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EIW77821.1 - 1.6e-07 30.9 0.0 0.00028 20.3 0.0 2.4 2 1 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EIW77821.1 - 6.3e-06 26.4 0.2 1.6e-05 25.0 0.1 1.8 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain PP2C PF00481.16 EIW77822.1 - 2.5e-05 23.8 0.0 0.018 14.4 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 EIW77822.1 - 5.5e-05 22.9 0.0 7.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EIW77822.1 - 0.0015 18.0 0.0 0.0027 17.1 0.0 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C Proteasome PF00227.21 EIW77823.1 - 8.8e-47 158.8 0.1 1.1e-46 158.5 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EIW77823.1 - 2.6e-12 45.7 0.1 5.3e-12 44.7 0.1 1.6 1 0 0 1 1 1 1 Proteasome beta subunits C terminal BAR_2 PF10455.4 EIW77824.1 - 1.1e-44 152.5 0.0 2.5e-44 151.3 0.0 1.5 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EIW77824.1 - 5.4e-13 48.9 0.6 9.5e-12 44.9 0.4 2.0 1 1 0 1 1 1 1 BAR domain Uds1 PF15456.1 EIW77824.1 - 0.1 12.6 2.9 0.84 9.6 0.0 2.7 2 1 0 2 2 2 0 Up-regulated During Septation DUF1156 PF06634.7 EIW77825.1 - 0.17 11.7 0.5 0.36 10.6 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) Aldedh PF00171.17 EIW77826.1 - 2.9e-124 414.9 0.1 3.6e-124 414.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIW77826.1 - 3.6e-08 32.5 0.0 6.1e-08 31.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) EMP24_GP25L PF01105.19 EIW77827.1 - 6.5e-44 149.8 0.1 7.5e-44 149.6 0.1 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Cation_ATPase_C PF00689.16 EIW77827.1 - 0.15 11.5 0.1 0.15 11.5 0.1 1.5 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Amidohydro_4 PF13147.1 EIW77828.1 - 2.7e-17 63.7 3.3 6.6e-10 39.4 0.0 3.2 3 1 0 3 3 3 2 Amidohydrolase Amidohydro_5 PF13594.1 EIW77828.1 - 9.5e-15 54.1 0.7 3.4e-14 52.3 0.5 2.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EIW77828.1 - 3.1e-14 53.3 0.0 4.2e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 EIW77828.1 - 6.6e-08 32.1 0.9 0.0086 15.3 0.4 2.5 2 0 0 2 2 2 2 Amidohydrolase family PD40 PF07676.7 EIW77828.1 - 1.1e-06 28.1 0.8 0.13 11.9 0.0 3.7 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat DUF4451 PF14616.1 EIW77829.1 - 2.1e-25 88.9 1.6 1.3e-17 63.6 0.7 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4451) Sdh5 PF03937.11 EIW77831.1 - 5.9e-25 86.7 0.9 9.3e-25 86.1 0.6 1.3 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase EnY2 PF10163.4 EIW77832.1 - 8.1e-18 64.1 0.0 9.1e-18 63.9 0.0 1.0 1 0 0 1 1 1 1 Transcription factor e(y)2 DUF3849 PF12960.2 EIW77832.1 - 0.078 12.9 0.0 0.085 12.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) Ribosomal_S10 PF00338.17 EIW77833.1 - 1.3e-23 82.6 0.0 2.7e-23 81.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Mago_nashi PF02792.9 EIW77834.1 - 8.1e-75 249.3 0.4 9.6e-75 249.0 0.3 1.0 1 0 0 1 1 1 1 Mago nashi protein DUF3506 PF12014.3 EIW77834.1 - 0.095 12.5 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) Pkinase PF00069.20 EIW77836.1 - 3e-28 98.7 0.0 3.2e-28 98.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW77836.1 - 8.3e-10 38.1 0.0 9.2e-10 38.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW77836.1 - 0.024 14.3 0.0 0.14 11.8 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family MRG PF05712.8 EIW77837.1 - 2.9e-49 166.6 0.0 4.2e-49 166.1 0.0 1.1 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EIW77837.1 - 7.2e-10 38.4 0.2 1.2e-09 37.6 0.1 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.19 EIW77837.1 - 0.073 12.7 0.2 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Redoxin PF08534.5 EIW77839.1 - 5.4e-28 97.3 0.0 6e-28 97.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EIW77839.1 - 5.2e-11 42.3 0.0 8.8e-11 41.5 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA family Herpes_gE PF02480.11 EIW77840.1 - 0.017 13.4 0.0 0.028 12.6 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Flagellin_IN PF07196.8 EIW77840.1 - 0.11 12.5 0.3 0.23 11.4 0.2 1.4 1 0 0 1 1 1 0 Flagellin hook IN motif Proteasome PF00227.21 EIW77841.1 - 5.4e-28 97.5 0.1 6.5e-28 97.3 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Glycos_trans_3N PF02885.12 EIW77841.1 - 0.1 12.1 0.2 5.1 6.7 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain HA2 PF04408.18 EIW77842.1 - 3.4e-26 91.2 0.1 8.3e-26 89.9 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EIW77842.1 - 1.3e-25 89.4 0.0 3.5e-25 88.0 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EIW77842.1 - 1.1e-10 41.2 0.0 2.1e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIW77842.1 - 2.3e-07 30.4 0.2 5.1e-07 29.3 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.17 EIW77842.1 - 8.7e-05 22.0 0.2 0.00029 20.3 0.1 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.1 EIW77842.1 - 0.00017 21.7 0.1 0.00077 19.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EIW77842.1 - 0.023 14.5 0.0 7.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EIW77842.1 - 0.044 13.5 0.1 0.092 12.4 0.1 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain T2SE PF00437.15 EIW77842.1 - 0.064 12.1 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 EIW77842.1 - 0.11 12.7 0.1 0.49 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EIW77842.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain SKG6 PF08693.5 EIW77843.1 - 0.0019 17.4 0.0 0.0031 16.7 0.0 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 EIW77843.1 - 0.052 13.0 0.0 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Syndecan PF01034.15 EIW77843.1 - 0.054 13.1 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain TMEM51 PF15345.1 EIW77843.1 - 0.085 12.5 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Mg_chelatase PF01078.16 EIW77843.1 - 0.12 11.4 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DIOX_N PF14226.1 EIW77844.1 - 7.5e-16 58.7 0.0 1.7e-15 57.5 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIW77844.1 - 4.7e-09 36.4 0.0 7.7e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SKG6 PF08693.5 EIW77845.1 - 0.0044 16.3 0.3 0.013 14.8 0.2 1.8 1 1 0 1 1 1 1 Transmembrane alpha-helix domain HemX PF04375.9 EIW77845.1 - 0.005 15.4 0.1 0.0066 15.0 0.1 1.1 1 0 0 1 1 1 1 HemX Herpes_gE PF02480.11 EIW77845.1 - 0.013 13.7 0.0 0.019 13.2 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1517 PF07466.6 EIW77845.1 - 0.02 13.9 0.3 0.033 13.1 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF1573 PF07610.6 EIW77845.1 - 0.033 13.7 0.4 0.068 12.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1573) Pyr_excise PF03013.9 EIW77845.1 - 0.038 13.7 0.0 0.064 13.0 0.0 1.3 1 0 0 1 1 1 0 Pyrimidine dimer DNA glycosylase Terpene_synth_C PF03936.11 EIW77846.1 - 3.9e-07 29.5 0.1 7.2e-07 28.7 0.0 1.4 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain PA_decarbox PF05870.6 EIW77846.1 - 0.065 12.6 0.0 0.48 9.8 0.0 2.1 2 0 0 2 2 2 0 Phenolic acid decarboxylase (PAD) zf-B_box PF00643.19 EIW77848.1 - 0.21 11.4 11.4 0.12 12.2 5.4 2.2 2 0 0 2 2 2 0 B-box zinc finger RVT_1 PF00078.22 EIW77850.1 - 4.8e-08 32.6 0.1 5e-08 32.5 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RNase_H PF00075.19 EIW77851.1 - 7.7e-12 45.6 0.0 1.3e-11 44.9 0.0 1.4 2 0 0 2 2 2 1 RNase H Terpene_synth_C PF03936.11 EIW77853.1 - 5.2e-12 45.5 0.3 1.8e-10 40.5 0.0 2.1 2 0 0 2 2 2 2 Terpene synthase family, metal binding domain Septin PF00735.13 EIW77855.1 - 2.4e-114 381.1 0.3 3.5e-114 380.5 0.2 1.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EIW77855.1 - 7.6e-07 29.1 0.0 1.7e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIW77855.1 - 1.6e-06 27.7 0.1 0.00011 21.7 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EIW77855.1 - 6.1e-06 25.5 0.0 1.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EIW77855.1 - 0.0013 18.2 1.6 0.087 12.3 0.1 2.9 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EIW77855.1 - 0.0013 19.2 0.1 0.0043 17.5 0.1 1.9 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EIW77855.1 - 0.0014 18.0 0.3 0.0059 16.0 0.2 2.1 1 1 0 1 1 1 1 Ras family AAA_22 PF13401.1 EIW77855.1 - 0.0024 18.0 2.3 0.028 14.5 0.0 3.0 3 1 0 3 3 3 1 AAA domain ABC_tran PF00005.22 EIW77855.1 - 0.0045 17.2 0.2 0.018 15.3 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_10 PF12846.2 EIW77855.1 - 0.0046 16.4 0.0 0.0069 15.8 0.0 1.6 1 1 0 1 1 1 1 AAA-like domain AAA_16 PF13191.1 EIW77855.1 - 0.0064 16.5 2.4 0.023 14.6 0.0 2.6 3 0 0 3 3 3 1 AAA ATPase domain Bac_DnaA PF00308.13 EIW77855.1 - 0.0066 16.1 1.0 0.34 10.5 0.0 2.4 2 0 0 2 2 2 1 Bacterial dnaA protein AIG1 PF04548.11 EIW77855.1 - 0.0073 15.4 0.1 0.019 14.1 0.0 1.7 2 0 0 2 2 2 1 AIG1 family AAA_24 PF13479.1 EIW77855.1 - 0.01 15.4 0.0 0.018 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EIW77855.1 - 0.028 14.0 0.0 0.058 13.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 EIW77855.1 - 0.03 13.1 0.4 0.074 11.8 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain Pox_A32 PF04665.7 EIW77855.1 - 0.04 13.2 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein FtsK_SpoIIIE PF01580.13 EIW77855.1 - 0.046 13.1 3.3 0.05 13.0 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.1 EIW77855.1 - 0.072 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activat PF00158.21 EIW77855.1 - 0.08 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Dynamin_N PF00350.18 EIW77855.1 - 0.093 12.5 5.4 3.3 7.4 0.1 2.9 2 1 1 3 3 3 0 Dynamin family Mg_chelatase PF01078.16 EIW77855.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA PF00004.24 EIW77855.1 - 0.46 10.6 2.7 0.6 10.3 0.2 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Myc-LZ PF02344.10 EIW77855.1 - 0.51 10.0 5.0 6.3 6.5 0.2 2.6 2 0 0 2 2 2 0 Myc leucine zipper domain GON PF08685.6 EIW77857.1 - 0.14 11.9 0.1 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 GON domain HA2 PF04408.18 EIW77858.1 - 5.3e-26 90.6 0.1 1.3e-25 89.3 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EIW77858.1 - 2e-25 88.8 0.0 5.2e-25 87.4 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EIW77858.1 - 8.8e-11 41.5 0.0 1.9e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIW77858.1 - 1e-05 25.0 1.4 5.2e-05 22.7 1.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EIW77858.1 - 0.0002 21.4 0.0 0.00064 19.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 EIW77858.1 - 0.00091 18.7 0.2 0.0031 16.9 0.1 2.0 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 EIW77858.1 - 0.028 14.2 0.1 8.7 6.1 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit T2SE PF00437.15 EIW77858.1 - 0.081 11.8 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Flavi_DEAD PF07652.9 EIW77858.1 - 0.1 12.3 0.1 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain KaiC PF06745.8 EIW77858.1 - 0.15 11.1 0.0 0.73 8.9 0.0 2.1 3 0 0 3 3 3 0 KaiC AAA_23 PF13476.1 EIW77858.1 - 0.16 12.3 0.1 0.57 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain Ribosomal_S3_C PF00189.15 EIW77859.1 - 1.2e-16 60.6 0.1 2.4e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EIW77859.1 - 4.7e-12 45.2 0.0 7.9e-12 44.5 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EIW77859.1 - 0.02 15.1 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 FtsJ PF01728.14 EIW77860.1 - 6.1e-43 146.9 0.0 7.6e-43 146.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Peptidase_A4 PF01828.12 EIW77861.1 - 4.9e-50 169.4 9.3 5.5e-50 169.3 6.5 1.0 1 0 0 1 1 1 1 Peptidase A4 family Thaumatin PF00314.12 EIW77862.1 - 1.6e-08 34.3 9.2 1.5e-07 31.1 6.3 2.1 1 1 0 1 1 1 1 Thaumatin family MFS_1 PF07690.11 EIW77864.1 - 6.2e-49 166.5 51.7 2.3e-48 164.6 35.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DnaJ-X PF14308.1 EIW77865.1 - 8.1e-52 175.4 1.5 8.1e-52 175.4 1.1 1.8 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 EIW77865.1 - 2.8e-27 94.2 1.5 1.1e-26 92.3 1.0 2.1 1 0 0 1 1 1 1 DnaJ domain zinc_ribbon_5 PF13719.1 EIW77865.1 - 0.013 15.0 2.4 0.037 13.5 1.6 1.8 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EIW77865.1 - 0.081 12.6 4.7 0.22 11.2 3.2 1.8 1 1 0 1 1 1 0 zinc-ribbon domain Mu-like_Pro PF10123.4 EIW77865.1 - 7.8 5.8 11.1 1.1 8.5 3.0 2.3 2 1 1 3 3 3 0 Mu-like prophage I protein DUF3328 PF11807.3 EIW77866.1 - 2.1e-18 66.7 4.6 9.2e-18 64.7 3.2 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF1381 PF07129.6 EIW77868.1 - 0.001 18.4 2.1 46 3.5 0.0 5.5 6 0 0 6 6 6 0 Protein of unknown function (DUF1381) Retinin_C PF04527.7 EIW77868.1 - 0.05 13.6 0.6 11 6.1 0.1 3.1 1 1 1 2 2 2 0 Drosophila Retinin like protein Sorb PF02208.11 EIW77868.1 - 0.051 12.9 0.0 1.6 8.1 0.0 3.3 4 1 1 5 5 5 0 Sorbin homologous domain FA PF08736.6 EIW77868.1 - 0.15 11.8 2.3 1.9 8.3 0.1 3.2 2 1 3 5 5 5 0 FERM adjacent (FA) KCNQC3-Ank-G_bd PF11956.3 EIW77868.1 - 3.8 7.6 5.2 48 4.0 1.3 3.3 1 1 2 3 3 3 0 Ankyrin-G binding motif of KCNQ2-3 MFS_1 PF07690.11 EIW77869.1 - 1.6e-37 129.0 29.8 1.6e-37 129.0 20.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW77869.1 - 2.3e-14 52.8 20.7 3.2e-14 52.3 14.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW77870.1 - 1.3e-29 103.0 55.1 3.8e-25 88.3 18.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2345 PF10106.4 EIW77870.1 - 0.026 14.1 0.1 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2345) MFS_1 PF07690.11 EIW77871.1 - 5.3e-44 150.3 67.1 1.9e-34 118.9 26.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily tRNA-synt_1b PF00579.20 EIW77872.1 - 2.3e-55 187.8 0.0 4.3e-54 183.6 0.0 2.0 2 0 0 2 2 2 2 tRNA synthetases class I (W and Y) Polysacc_deac_1 PF01522.16 EIW77874.1 - 8.4e-28 96.4 0.0 1.5e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF1249 PF06853.7 EIW77874.1 - 0.062 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1249) Serglycin PF04360.7 EIW77874.1 - 1.1 8.9 6.8 2.2 8.0 4.7 1.5 1 0 0 1 1 1 0 Serglycin Herpes_gE PF02480.11 EIW77876.1 - 0.00011 20.5 0.0 0.12 10.6 0.0 2.1 2 0 0 2 2 2 2 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 EIW77876.1 - 0.00028 19.8 0.0 0.074 11.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1191) Syndecan PF01034.15 EIW77876.1 - 0.00038 20.0 0.1 0.3 10.7 0.0 2.4 2 0 0 2 2 2 2 Syndecan domain Yip1 PF04893.12 EIW77876.1 - 0.0063 16.0 1.1 4 6.9 0.0 3.0 3 0 0 3 3 3 2 Yip1 domain Phage_HK97_TLTM PF06120.6 EIW77876.1 - 0.0083 15.5 0.5 0.43 9.8 0.0 2.2 2 0 0 2 2 2 1 Tail length tape measure protein Sec66 PF09802.4 EIW77876.1 - 0.021 14.2 0.0 6.3 6.1 0.0 2.1 2 0 0 2 2 2 0 Preprotein translocase subunit Sec66 Gly-zipper_OmpA PF13436.1 EIW77876.1 - 0.044 13.4 0.2 4.3 7.0 0.0 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain SKG6 PF08693.5 EIW77876.1 - 0.048 12.9 1.2 0.064 12.5 0.0 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain DUF456 PF04306.8 EIW77876.1 - 0.061 13.3 6.9 0.74 9.8 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF456) Gly-zipper_Omp PF13488.1 EIW77876.1 - 0.093 12.3 10.5 3.4 7.3 0.2 2.9 2 1 0 2 2 2 0 Glycine zipper Lysis_S PF04971.7 EIW77876.1 - 0.14 11.8 2.3 13 5.5 0.1 2.7 2 0 0 2 2 2 0 Lysis protein S Amnionless PF14828.1 EIW77876.1 - 0.21 10.0 0.0 8.2 4.7 0.0 2.0 2 0 0 2 2 2 0 Amnionless p450 PF00067.17 EIW77877.1 - 6.9e-67 225.9 0.0 8.3e-67 225.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4243 PF14027.1 EIW77878.1 - 4.6e-86 289.2 0.2 6.2e-86 288.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) p450 PF00067.17 EIW77879.1 - 5.3e-70 236.2 0.0 6.5e-70 235.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transposase_21 PF02992.9 EIW77880.1 - 2.6e-12 46.3 0.1 8.2e-12 44.6 0.0 1.7 2 0 0 2 2 2 1 Transposase family tnp2 p450 PF00067.17 EIW77883.1 - 3.1e-65 220.5 0.0 4e-65 220.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3445 PF11927.3 EIW77884.1 - 6.8e-65 218.9 0.0 1.2e-49 168.9 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3445) CbiM PF01891.11 EIW77885.1 - 0.058 13.0 0.8 0.1 12.2 0.6 1.3 1 0 0 1 1 1 0 Cobalt uptake substrate-specific transmembrane region Glycophorin_A PF01102.13 EIW77885.1 - 0.063 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A Cyt-b5 PF00173.23 EIW77887.1 - 2.4e-10 40.0 0.0 3.2e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Tombus_P33 PF08500.5 EIW77889.1 - 0.087 12.5 0.0 4.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Tombusvirus p33 DUF4094 PF13334.1 EIW77892.1 - 0.02 15.2 1.4 0.02 15.2 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) Imm29 PF15575.1 EIW77892.1 - 0.12 11.9 0.1 0.26 10.8 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 29 TPR_10 PF13374.1 EIW77893.1 - 1.1e-73 241.3 1.2 1.4e-07 31.1 0.0 11.1 11 0 0 11 11 11 11 Tetratricopeptide repeat TPR_12 PF13424.1 EIW77893.1 - 3.1e-64 212.8 9.4 5e-12 45.5 0.1 7.2 4 2 2 7 7 7 7 Tetratricopeptide repeat TPR_11 PF13414.1 EIW77893.1 - 4.8e-17 61.3 2.5 0.00039 20.0 0.2 7.5 5 2 3 8 8 8 4 TPR repeat TPR_17 PF13431.1 EIW77893.1 - 3.1e-15 55.0 0.1 2.6 8.4 0.0 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.1 EIW77893.1 - 4.8e-14 52.5 4.5 0.0012 19.4 0.0 6.7 4 2 2 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 EIW77893.1 - 8.2e-13 47.2 5.8 0.059 13.3 0.4 8.7 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 EIW77893.1 - 6e-12 44.4 9.6 0.044 13.5 0.1 8.5 10 1 0 10 10 9 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIW77893.1 - 5.8e-11 42.5 3.3 0.095 13.0 0.0 7.1 5 1 3 8 8 8 3 Tetratricopeptide repeat TPR_4 PF07721.9 EIW77893.1 - 4.6e-10 38.9 1.5 21 5.9 0.0 8.6 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIW77893.1 - 7.3e-10 38.5 8.8 1.4 9.7 0.0 9.1 6 3 3 9 9 9 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIW77893.1 - 3.2e-07 29.6 9.4 0.0092 15.5 0.4 6.8 9 0 0 9 9 9 2 Tetratricopeptide repeat PPR PF01535.15 EIW77893.1 - 0.00072 19.3 2.2 38 4.5 0.0 6.2 8 0 0 8 8 7 0 PPR repeat HHH_3 PF12836.2 EIW77893.1 - 0.079 12.9 1.2 2.6 8.0 0.0 3.8 4 1 1 5 5 5 0 Helix-hairpin-helix motif TPR_8 PF13181.1 EIW77893.1 - 0.13 12.0 10.1 65 3.6 0.0 6.5 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIW77893.1 - 1.1 9.9 5.8 1.5e+02 3.2 0.0 5.5 7 0 0 7 7 5 0 Tetratricopeptide repeat TPR_3 PF07720.7 EIW77893.1 - 2.9 7.7 10.5 31 4.5 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF1510 PF07423.6 EIW77894.1 - 0.052 12.8 9.6 0.084 12.2 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF605 PF04652.11 EIW77894.1 - 0.69 9.2 26.4 1.1 8.5 18.3 1.4 1 0 0 1 1 1 0 Vta1 like Suf PF05843.9 EIW77894.1 - 1.8 8.2 9.8 3 7.4 6.8 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.11 EIW77894.1 - 3.1 7.6 5.6 5.8 6.7 3.9 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Rtf2 PF04641.7 EIW77894.1 - 3.8 6.6 12.5 6.2 5.9 8.7 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Hid1 PF12722.2 EIW77894.1 - 6.8 4.2 6.5 9.4 3.7 4.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Methyltransf_15 PF09445.5 EIW77895.1 - 0.021 14.3 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Patatin PF01734.17 EIW77896.1 - 5.8e-19 68.8 0.0 8.7e-18 64.9 0.0 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase NB-ARC PF00931.17 EIW77896.1 - 8.2e-07 28.1 0.1 5.7e-06 25.4 0.0 2.0 1 1 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 EIW77896.1 - 4.6e-05 23.1 0.0 9.3e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW77896.1 - 0.00027 21.0 0.2 0.0012 18.8 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EIW77896.1 - 0.011 15.4 0.0 0.042 13.6 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain Zeta_toxin PF06414.7 EIW77896.1 - 0.022 13.8 0.4 0.039 13.0 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin DUF2075 PF09848.4 EIW77896.1 - 0.029 13.3 0.0 0.044 12.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TrwB_AAD_bind PF10412.4 EIW77896.1 - 0.034 12.7 0.0 0.065 11.8 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.1 EIW77896.1 - 0.039 14.0 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF1651 PF07864.6 EIW77896.1 - 0.053 13.6 0.1 7.1 6.8 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1651) IstB_IS21 PF01695.12 EIW77896.1 - 0.085 12.2 0.1 0.25 10.7 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA PF00004.24 EIW77896.1 - 0.1 12.8 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sld5 PF05916.6 EIW77897.1 - 1.3e-05 25.4 2.1 3.9e-05 23.8 1.2 2.0 1 1 0 1 1 1 1 GINS complex protein CBFD_NFYB_HMF PF00808.18 EIW77898.1 - 4.8e-16 58.5 0.9 7.4e-16 57.9 0.6 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EIW77898.1 - 2e-08 34.2 0.3 3.3e-08 33.5 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 U79_P34 PF03064.11 EIW77898.1 - 5.9 6.3 11.5 8.4 5.8 8.0 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 CPSase_L_D2 PF02786.12 EIW77899.1 - 7.3e-116 384.8 0.2 1.1e-82 276.3 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EIW77899.1 - 2.5e-47 159.6 0.0 1.1e-46 157.5 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EIW77899.1 - 4.4e-45 153.4 0.0 4.8e-44 150.1 0.0 2.4 2 0 0 2 2 2 1 Glutamine amidotransferase class-I OTCace_N PF02729.16 EIW77899.1 - 5.2e-44 149.3 0.0 1.1e-43 148.2 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 EIW77899.1 - 1.5e-41 141.0 0.1 3.2e-41 139.9 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EIW77899.1 - 1.7e-40 137.5 0.0 5.8e-19 68.2 0.0 2.9 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EIW77899.1 - 2.3e-38 131.7 0.2 4.4e-23 81.9 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain OTCace PF00185.19 EIW77899.1 - 1.5e-37 128.8 0.1 4.7e-37 127.2 0.0 1.9 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 EIW77899.1 - 1.2e-23 83.4 0.1 2.4e-10 39.6 0.0 3.9 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 EIW77899.1 - 1.2e-18 66.8 0.0 5.4e-18 64.7 0.0 2.3 2 0 0 2 2 1 1 MGS-like domain ATP-grasp PF02222.17 EIW77899.1 - 1.6e-17 63.3 0.1 2.3e-08 33.5 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EIW77899.1 - 8.5e-17 61.2 0.1 1.2e-08 34.5 0.0 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EIW77899.1 - 2.2e-06 27.2 0.0 0.0012 18.3 0.0 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EIW77899.1 - 2.2e-05 24.3 0.1 0.068 13.0 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EIW77899.1 - 0.00014 21.3 0.0 0.004 16.6 0.0 2.6 1 1 0 1 1 1 1 Peptidase C26 GARS_A PF01071.14 EIW77899.1 - 0.022 14.3 0.0 0.39 10.2 0.0 2.4 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 EIW77899.1 - 0.049 12.8 0.0 0.78 8.9 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain Vps5 PF09325.5 EIW77899.1 - 0.19 10.9 0.0 0.39 9.9 0.0 1.5 1 0 0 1 1 1 0 Vps5 C terminal like Tubulin PF00091.20 EIW77901.1 - 9.6e-70 234.7 0.0 1.9e-69 233.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIW77901.1 - 4.5e-49 165.6 0.2 7.1e-49 165.0 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EIW77901.1 - 1.1e-06 28.6 0.0 3e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EIW77901.1 - 0.039 13.4 0.0 0.085 12.3 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain GMC_oxred_N PF00732.14 EIW77902.1 - 1.3e-56 191.9 0.0 1.6e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIW77902.1 - 3.3e-31 108.5 0.0 7e-31 107.4 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIW77902.1 - 9.1e-06 24.8 0.1 0.00042 19.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIW77902.1 - 0.006 16.6 0.5 1.2 9.1 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW77902.1 - 0.012 15.9 1.5 0.065 13.6 0.4 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIW77902.1 - 0.014 14.3 0.5 0.022 13.7 0.4 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 EIW77902.1 - 0.014 15.3 1.8 0.014 15.3 1.2 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EIW77902.1 - 0.071 12.1 0.2 0.13 11.2 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain FAD_binding_2 PF00890.19 EIW77902.1 - 0.1 11.4 3.0 0.42 9.3 0.8 2.2 2 0 0 2 2 2 0 FAD binding domain DUF3433 PF11915.3 EIW77903.1 - 4.7e-17 61.9 7.0 1.4e-16 60.4 4.9 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) FKBP_C PF00254.23 EIW77904.1 - 4.9e-31 106.6 0.0 5.6e-31 106.4 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cas_Csd1 PF09709.5 EIW77905.1 - 0.12 10.6 0.0 0.17 10.1 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csd1) DEAD PF00270.24 EIW77908.1 - 1.1e-13 51.0 0.0 2.5e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW77908.1 - 6.7e-11 41.8 0.1 1.8e-10 40.4 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW77908.1 - 0.0082 15.9 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Syndecan PF01034.15 EIW77910.1 - 0.011 15.3 0.2 0.02 14.5 0.2 1.3 1 0 0 1 1 1 0 Syndecan domain DUF1191 PF06697.7 EIW77910.1 - 0.032 13.0 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) COX14 PF14880.1 EIW77910.1 - 0.12 12.0 0.1 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c assembly Rick_17kDa_Anti PF05433.10 EIW77910.1 - 0.45 10.2 7.5 1.2 8.8 5.2 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain Bacteriocin_IIc PF10439.4 EIW77910.1 - 2.4 8.3 7.5 1.7 8.8 0.4 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.1 EIW77910.1 - 4.6 6.8 10.6 0.11 12.0 2.4 1.9 2 0 0 2 2 2 0 YMGG-like Gly-zipper p450 PF00067.17 EIW77912.1 - 3.3e-69 233.6 0.0 4e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2530 PF10745.4 EIW77912.1 - 0.1 12.5 0.2 25 4.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Beta-lactamase PF00144.19 EIW77913.1 - 9.4e-46 156.3 0.0 1.8e-45 155.4 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EIW77913.1 - 0.077 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase Pyr_redox_3 PF13738.1 EIW77914.1 - 1.8e-21 77.1 0.0 4.4e-21 75.8 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW77914.1 - 3.1e-11 42.7 0.0 3.3e-09 36.1 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EIW77914.1 - 3.9e-09 35.2 0.0 7.6e-09 34.3 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EIW77914.1 - 3.8e-07 30.0 0.1 8.9e-05 22.4 0.1 2.9 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIW77914.1 - 0.0022 18.3 0.1 0.98 9.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW77914.1 - 0.0051 16.7 0.0 9.5 6.0 0.0 3.3 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIW77914.1 - 0.0066 15.5 0.1 0.061 12.3 0.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EIW77914.1 - 0.053 12.4 0.9 0.2 10.4 0.1 2.2 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW77914.1 - 0.056 12.2 0.0 0.091 11.5 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.14 EIW77914.1 - 0.056 12.5 0.1 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EIW77914.1 - 0.086 12.6 2.6 0.41 10.4 0.0 2.8 3 1 1 4 4 4 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EIW77914.1 - 0.1 11.0 0.7 0.86 7.9 0.0 2.6 4 0 0 4 4 4 0 HI0933-like protein Thi4 PF01946.12 EIW77914.1 - 0.11 11.6 0.7 0.34 9.9 0.0 2.0 3 0 0 3 3 3 0 Thi4 family Lycopene_cycl PF05834.7 EIW77914.1 - 1.3 7.8 3.7 0.6 8.9 0.4 2.0 2 1 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EIW77915.1 - 2e-14 54.1 0.0 1.2e-13 51.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW77915.1 - 4.2e-09 35.7 0.0 5.6e-07 28.8 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EIW77915.1 - 1.4e-07 30.1 0.0 2.8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EIW77915.1 - 5.9e-05 23.0 0.0 0.001 19.0 0.0 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIW77915.1 - 0.00066 19.6 0.0 0.22 11.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EIW77915.1 - 0.002 17.3 0.0 0.0039 16.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TAFII28 PF04719.9 EIW77916.1 - 7.3e-29 99.4 0.0 9.5e-29 99.0 0.0 1.1 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.18 EIW77916.1 - 0.0021 18.0 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-C2H2_4 PF13894.1 EIW77917.1 - 0.0033 17.6 12.2 0.051 13.9 0.4 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-HYPF PF07503.7 EIW77917.1 - 1 8.8 4.4 0.29 10.5 0.8 1.8 2 0 0 2 2 2 0 HypF finger EamA PF00892.15 EIW77918.1 - 3.2e-26 91.8 22.9 7.4e-14 51.8 3.1 2.9 2 1 1 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EIW77918.1 - 1.2e-09 38.3 20.0 1.3e-08 35.0 1.3 3.4 3 1 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 EIW77918.1 - 8.8e-06 25.4 18.9 0.00066 19.3 5.9 2.8 2 1 0 2 2 2 2 Triose-phosphate Transporter family Polysacc_synt_C PF14667.1 EIW77918.1 - 0.0017 18.1 2.7 0.0017 18.1 1.9 3.7 3 1 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain DUF1516 PF07457.6 EIW77918.1 - 0.038 14.0 3.4 0.061 13.4 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1516) UAA PF08449.6 EIW77918.1 - 0.29 10.0 8.1 0.22 10.4 4.4 1.6 1 1 0 2 2 2 0 UAA transporter family EamA PF00892.15 EIW77919.1 - 1.6e-22 79.9 21.1 2.1e-11 43.9 6.4 2.3 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EIW77919.1 - 6.7e-11 42.3 17.2 3.4e-09 36.9 0.2 2.7 2 1 0 2 2 2 2 Multidrug resistance efflux transporter TPT PF03151.11 EIW77919.1 - 8.9e-06 25.4 10.3 8.9e-06 25.4 7.1 2.6 3 0 0 3 3 3 2 Triose-phosphate Transporter family Nuc_sug_transp PF04142.10 EIW77919.1 - 0.057 12.5 1.4 0.11 11.5 0.0 1.9 1 1 1 2 2 2 0 Nucleotide-sugar transporter Polysacc_synt_C PF14667.1 EIW77919.1 - 3.3 7.5 21.5 0.034 13.9 3.2 3.5 3 1 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain EamA PF00892.15 EIW77920.1 - 2.2e-22 79.4 25.2 8.5e-12 45.2 3.7 2.4 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EIW77920.1 - 1.5e-07 31.6 4.5 1.5e-07 31.6 3.1 3.0 2 2 1 3 3 3 1 Multidrug resistance efflux transporter DUF914 PF06027.7 EIW77920.1 - 0.0068 15.2 8.7 0.018 13.9 6.0 1.6 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EcsB PF05975.7 EIW77920.1 - 0.58 8.5 11.5 0.12 10.7 1.9 2.3 2 0 0 2 2 2 0 Bacterial ABC transporter protein EcsB Sec20 PF03908.8 EIW77920.1 - 2.8 7.7 5.0 1 9.0 0.4 2.2 2 0 0 2 2 2 0 Sec20 RseC_MucC PF04246.7 EIW77920.1 - 8 6.0 12.2 1.6 8.2 0.2 3.0 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC zf-H2C2_2 PF13465.1 EIW77921.1 - 1.2e-07 31.6 7.6 2.9e-07 30.4 0.3 3.7 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EIW77921.1 - 2e-06 27.8 21.3 1.8e-05 24.7 0.5 4.9 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EIW77921.1 - 3.4e-05 23.5 1.1 0.87 9.5 0.1 3.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EIW77921.1 - 0.001 19.2 14.4 0.0097 16.1 0.3 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger PsaX PF08078.7 EIW77922.1 - 0.017 14.9 3.7 0.045 13.6 2.6 1.7 1 0 0 1 1 1 0 PsaX family DUF3341 PF11821.3 EIW77922.1 - 0.025 14.0 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) Pex14_N PF04695.8 EIW77922.1 - 0.13 12.2 0.8 0.28 11.2 0.5 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MMR_HSR1 PF01926.18 EIW77923.1 - 7.6e-06 25.8 0.0 9.3e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIW77923.1 - 0.00022 21.7 0.0 0.00026 21.4 0.0 1.3 1 1 0 1 1 1 1 Miro-like protein MobB PF03205.9 EIW77923.1 - 0.00068 19.3 0.1 0.0054 16.4 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Arf PF00025.16 EIW77923.1 - 0.0015 17.8 0.0 0.002 17.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family NTPase_1 PF03266.10 EIW77923.1 - 0.014 15.1 0.0 0.014 15.1 0.0 1.2 1 0 0 1 1 1 0 NTPase AAA_17 PF13207.1 EIW77923.1 - 0.015 16.1 0.2 0.023 15.4 0.1 1.5 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EIW77923.1 - 0.024 14.1 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.22 EIW77923.1 - 0.044 14.0 0.0 0.048 13.9 0.0 1.2 1 0 0 1 1 1 0 ABC transporter GTP_EFTU PF00009.22 EIW77923.1 - 0.05 13.0 0.0 0.054 12.9 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain ATP-synt_ab PF00006.20 EIW77923.1 - 0.05 13.0 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain RHS_repeat PF05593.9 EIW77923.1 - 0.054 13.6 1.4 0.11 12.7 1.0 1.5 1 0 0 1 1 1 0 RHS Repeat Arch_ATPase PF01637.13 EIW77923.1 - 0.055 13.1 0.0 0.055 13.1 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase FeoB_N PF02421.13 EIW77923.1 - 0.075 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B NB-ARC PF00931.17 EIW77923.1 - 0.11 11.3 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF4243 PF14027.1 EIW77924.1 - 6.1e-83 278.9 0.1 7.5e-83 278.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Pkinase PF00069.20 EIW77925.1 - 2.3e-53 181.0 0.0 3.9e-53 180.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW77925.1 - 2.2e-27 95.7 0.0 3.2e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIW77925.1 - 0.061 12.3 0.0 0.098 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DEAD PF00270.24 EIW77928.1 - 1.8e-15 56.8 0.0 3.2e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW77928.1 - 5.5e-15 54.9 0.0 1.1e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW77928.1 - 4.5e-05 23.3 0.1 0.00013 21.8 0.1 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Glyco_hydro_76 PF03663.9 EIW77929.1 - 4.8e-40 138.0 27.1 6.4e-40 137.6 18.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 PIG-P PF08510.7 EIW77930.1 - 0.31 10.6 3.0 0.42 10.2 1.4 1.8 1 1 1 2 2 2 0 PIG-P DoxX_3 PF13781.1 EIW77930.1 - 2.4 8.5 7.7 0.17 12.2 1.8 1.8 2 0 0 2 2 2 0 DoxX-like family FA_hydroxylase PF04116.8 EIW77931.1 - 8.6e-13 48.6 21.9 8.6e-13 48.6 15.2 1.9 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Xan_ur_permease PF00860.15 EIW77932.1 - 2.5e-29 101.9 26.8 8e-18 64.0 7.8 2.4 3 0 0 3 3 3 2 Permease family Sulfate_transp PF00916.15 EIW77932.1 - 0.2 10.6 10.9 0.016 14.1 2.5 2.6 2 1 1 3 3 3 0 Sulfate transporter family FAD_binding_3 PF01494.14 EIW77934.1 - 4.1e-73 246.4 0.0 5.1e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIW77934.1 - 7.7e-06 25.9 1.5 3e-05 24.0 0.1 2.6 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIW77934.1 - 8.6e-06 25.0 0.2 5.1e-05 22.5 0.2 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EIW77934.1 - 4e-05 22.6 0.1 0.004 16.1 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EIW77934.1 - 6.5e-05 21.5 0.6 0.0016 16.9 0.1 2.7 2 1 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EIW77934.1 - 8.1e-05 21.6 0.1 0.0049 15.7 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EIW77934.1 - 0.00014 21.7 0.1 0.00098 19.1 0.0 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIW77934.1 - 0.00026 21.1 0.0 0.00072 19.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW77934.1 - 0.0011 19.2 0.1 0.15 12.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW77934.1 - 0.0016 17.6 0.0 0.0053 15.8 0.0 1.8 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.9 EIW77934.1 - 0.0064 15.1 0.1 0.041 12.5 0.0 1.9 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_9 PF13454.1 EIW77934.1 - 0.01 15.5 0.2 0.029 14.1 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 EIW77934.1 - 0.016 14.0 0.0 0.029 13.2 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A TrkA_N PF02254.13 EIW77934.1 - 0.039 13.9 0.8 0.17 11.8 0.0 2.4 3 0 0 3 3 2 0 TrkA-N domain HET PF06985.6 EIW77935.1 - 1.5e-18 67.2 3.9 4.5e-15 56.0 0.1 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) HET PF06985.6 EIW77936.1 - 4.3e-19 69.0 1.6 2.1e-15 57.1 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) PhyH PF05721.8 EIW77937.1 - 1.5e-12 47.9 0.2 2.1e-12 47.5 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glyco_transf_25 PF01755.12 EIW77938.1 - 8.1e-15 55.0 0.6 9.4e-07 28.6 0.1 3.1 2 1 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) TPT PF03151.11 EIW77940.1 - 0.22 11.1 10.1 0.44 10.1 6.5 1.9 1 1 0 1 1 1 0 Triose-phosphate Transporter family HNH PF01844.18 EIW77941.1 - 0.0034 17.2 4.9 0.0064 16.3 3.4 1.5 1 1 0 1 1 1 1 HNH endonuclease DIOX_N PF14226.1 EIW77942.1 - 5.9e-20 71.9 0.0 9e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIW77942.1 - 1.2e-19 70.4 0.0 1.7e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HNH PF01844.18 EIW77944.1 - 0.072 12.9 0.7 3.3 7.6 0.0 2.4 2 0 0 2 2 2 0 HNH endonuclease Iso_dh PF00180.15 EIW77945.1 - 0.055 12.4 0.5 4.4 6.1 0.1 2.3 2 1 0 2 2 2 0 Isocitrate/isopropylmalate dehydrogenase DUF4616 PF15394.1 EIW77946.1 - 0.0018 17.3 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4616) DUF4218 PF13960.1 EIW77947.1 - 0.00043 19.7 1.8 0.0015 17.9 0.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) Transposase_21 PF02992.9 EIW77947.1 - 0.001 18.2 2.2 0.0021 17.1 0.0 2.0 2 0 0 2 2 2 1 Transposase family tnp2 ADH_zinc_N PF00107.21 EIW77948.1 - 2.6e-18 65.7 1.1 3.8e-18 65.2 0.2 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW77948.1 - 1.7e-11 43.8 0.0 3.5e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIW77948.1 - 0.00034 21.4 0.1 0.001 19.9 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EIW77948.1 - 0.03 14.3 0.4 0.051 13.5 0.3 1.4 1 0 0 1 1 1 0 NADH(P)-binding LEH PF07858.7 EIW77948.1 - 0.14 12.1 0.1 0.41 10.6 0.0 1.7 1 1 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain RicinB_lectin_2 PF14200.1 EIW77949.1 - 1.6e-12 47.6 0.7 1.1e-05 25.7 0.1 2.3 1 1 2 3 3 3 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EIW77949.1 - 0.0012 18.8 0.0 0.032 14.2 0.0 1.9 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain Aldo_ket_red PF00248.16 EIW77950.1 - 4.8e-75 251.9 0.0 5.5e-75 251.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2648 PF10855.3 EIW77951.1 - 0.17 11.3 0.2 0.45 9.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) Glyco_hydro_20 PF00728.17 EIW77952.1 - 3.8e-36 124.9 0.0 2.7e-35 122.1 0.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.10 EIW77952.1 - 4.2e-07 30.5 0.0 8.7e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Amidohydro_5 PF13594.1 EIW77953.1 - 1.4e-08 34.4 0.0 1.3e-07 31.3 0.0 2.5 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 EIW77953.1 - 2.3e-06 27.4 0.0 6.2e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EIW77953.1 - 3.3e-06 27.3 0.3 6.6e-05 23.0 0.2 2.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EIW77953.1 - 3.6e-06 26.4 0.1 7.6e-05 22.0 0.0 2.4 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_1 PF01979.15 EIW77954.1 - 1.5e-09 38.0 0.2 4e-09 36.5 0.1 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EIW77954.1 - 6.3e-09 35.5 0.0 1.7e-08 34.1 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EIW77954.1 - 2.6e-05 24.4 0.3 0.065 13.2 0.1 2.4 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EIW77954.1 - 0.0002 20.7 4.2 0.021 14.0 0.5 3.4 1 1 0 2 2 2 1 Amidohydrolase family Response_reg PF00072.19 EIW77954.1 - 0.017 15.0 1.6 0.048 13.6 0.4 2.2 2 1 0 2 2 2 0 Response regulator receiver domain Abhydrolase_6 PF12697.2 EIW77955.1 - 9.7e-36 123.7 0.6 1.3e-35 123.3 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW77955.1 - 1.1e-18 67.4 0.1 2.8e-18 66.0 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW77955.1 - 2e-17 63.5 0.0 5.8e-11 42.3 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF915 PF06028.6 EIW77955.1 - 7.1e-05 22.0 0.0 0.0079 15.3 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF676 PF05057.9 EIW77955.1 - 0.00087 18.6 0.0 0.12 11.6 0.0 2.2 2 0 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EIW77955.1 - 0.0022 17.6 1.2 0.013 15.1 0.9 1.9 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.3 EIW77955.1 - 0.0037 17.0 0.0 0.009 15.8 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 EIW77955.1 - 0.0043 15.5 0.0 0.0066 14.9 0.0 1.3 1 0 0 1 1 1 1 Ndr family Esterase PF00756.15 EIW77955.1 - 0.0066 15.9 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Lipase_3 PF01764.20 EIW77955.1 - 0.01 15.4 0.2 0.029 13.9 0.0 1.7 1 1 0 2 2 2 0 Lipase (class 3) Abhydrolase_4 PF08386.5 EIW77955.1 - 0.012 15.4 0.0 0.033 14.0 0.0 1.7 2 0 0 2 2 2 0 TAP-like protein Ser_hydrolase PF06821.8 EIW77955.1 - 0.027 14.0 0.0 4.1 6.9 0.0 2.3 2 1 0 2 2 2 0 Serine hydrolase Abhydrolase_2 PF02230.11 EIW77955.1 - 0.053 12.9 0.0 4.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF1749 PF08538.5 EIW77955.1 - 0.054 12.3 0.0 0.21 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1749) Abhydro_lipase PF04083.11 EIW77955.1 - 0.059 12.7 0.1 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Peptidase_S9 PF00326.16 EIW77955.1 - 0.086 12.0 0.0 2.1 7.5 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family DLH PF01738.13 EIW77955.1 - 0.1 11.8 0.0 4.9 6.3 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Methyltransf_23 PF13489.1 EIW77956.1 - 3.9e-14 52.6 0.0 5.1e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW77956.1 - 3.6e-08 33.7 0.0 6.3e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW77956.1 - 2.9e-06 27.6 0.0 6.4e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW77956.1 - 7e-06 25.6 0.0 1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW77956.1 - 0.00016 22.1 0.0 0.00033 21.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PAP2 PF01569.16 EIW77957.1 - 1.3e-09 37.8 13.8 4.6e-09 36.0 9.6 2.2 1 1 0 1 1 1 1 PAP2 superfamily PAP2_3 PF14378.1 EIW77957.1 - 4.5e-09 36.1 6.6 4.5e-09 36.1 4.6 1.6 2 0 0 2 2 2 1 PAP2 superfamily Proteasome PF00227.21 EIW77959.1 - 5.2e-45 153.0 0.2 6.3e-45 152.7 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Ribonuclease_T2 PF00445.13 EIW77960.1 - 1.1e-37 129.5 0.0 1.6e-37 128.9 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family SNARE_assoc PF09335.6 EIW77961.1 - 1.8e-17 63.6 6.9 1.8e-17 63.6 4.8 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein Lig_chan PF00060.21 EIW77961.1 - 0.41 10.3 8.9 0.15 11.7 1.4 2.6 3 0 0 3 3 3 0 Ligand-gated ion channel PLDc_N PF13396.1 EIW77961.1 - 5.9 6.6 12.5 0.059 13.0 1.3 2.7 3 0 0 3 3 3 0 Phospholipase_D-nuclease N-terminal Pkinase PF00069.20 EIW77962.1 - 4.3e-34 117.8 0.0 1e-33 116.6 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW77962.1 - 8.7e-33 113.4 0.0 1.4e-32 112.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW77962.1 - 6.3e-05 22.8 0.0 0.00017 21.4 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4238 PF14022.1 EIW77962.1 - 0.00077 18.8 0.0 0.23 10.6 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4238) Fructosamin_kin PF03881.9 EIW77962.1 - 0.01 14.8 0.0 0.024 13.6 0.0 1.5 2 0 0 2 2 2 0 Fructosamine kinase DUF4243 PF14027.1 EIW77963.1 - 1.9e-91 306.9 0.3 2.3e-91 306.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) YfzA PF14118.1 EIW77963.1 - 0.18 11.9 0.4 2.6 8.2 0.0 2.2 2 0 0 2 2 2 0 YfzA-like protein Oxidored_FMN PF00724.15 EIW77964.1 - 4.5e-101 338.2 0.0 5.2e-101 338.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Peptidase_M36 PF02128.10 EIW77966.1 - 9.8e-122 406.4 4.6 1.1e-97 327.2 1.6 2.2 2 0 0 2 2 2 2 Fungalysin metallopeptidase (M36) FTP PF07504.8 EIW77966.1 - 8.4e-08 31.5 0.6 1.9e-07 30.4 0.4 1.7 1 0 0 1 1 1 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 EIW77966.1 - 0.036 13.7 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 Thermolysin metallopeptidase, alpha-helical domain SAM_MT PF04445.8 EIW77966.1 - 0.23 10.5 0.0 0.37 9.9 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Ras PF00071.17 EIW77967.1 - 2.5e-55 186.2 0.0 2.9e-55 186.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW77967.1 - 4.5e-18 65.8 0.0 6.9e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW77967.1 - 2.6e-14 52.8 0.0 3.1e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW77967.1 - 9.4e-07 28.1 0.0 1.1e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EIW77967.1 - 1.9e-06 27.7 0.0 3.3e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIW77967.1 - 0.00011 21.6 0.0 0.00026 20.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EIW77967.1 - 0.041 13.0 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EIW77967.1 - 0.077 11.6 0.3 1.3 7.6 0.0 2.0 1 1 1 2 2 2 0 G-protein alpha subunit Dynamin_N PF00350.18 EIW77967.1 - 0.086 12.6 0.0 0.2 11.4 0.0 1.6 1 1 1 2 2 2 0 Dynamin family Septin PF00735.13 EIW77967.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Septin ADH_zinc_N PF00107.21 EIW77971.1 - 2.2e-16 59.6 0.6 1.5e-15 56.9 0.1 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW77971.1 - 7.8e-12 44.9 0.2 2e-11 43.6 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIW77971.1 - 1.9e-05 25.5 0.5 5.3e-05 24.1 0.1 1.9 2 1 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EIW77971.1 - 0.036 14.0 0.2 0.062 13.2 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding Oxidored_FMN PF00724.15 EIW77973.1 - 6.5e-103 344.3 0.0 7.4e-103 344.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family TrbE PF11100.3 EIW77974.1 - 0.54 10.1 3.7 2.8 7.8 0.1 2.7 2 0 0 2 2 2 0 Conjugal transfer protein TrbE dsrm PF00035.20 EIW77975.1 - 0.037 14.6 0.2 6.2 7.4 0.0 4.0 4 0 0 4 4 4 0 Double-stranded RNA binding motif NTPase_1 PF03266.10 EIW77975.1 - 0.16 11.6 0.3 16 5.1 0.1 2.2 2 0 0 2 2 2 0 NTPase Thaumatin PF00314.12 EIW77976.1 - 4.5e-15 55.6 9.2 5.8e-15 55.3 6.4 1.2 1 0 0 1 1 1 1 Thaumatin family adh_short PF00106.20 EIW77977.1 - 8e-28 97.4 0.0 1.1e-27 97.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW77977.1 - 6.9e-17 62.0 0.0 1e-16 61.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW77977.1 - 1.8e-06 27.7 0.0 2.7e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIW77977.1 - 0.0001 22.3 0.0 0.00023 21.1 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EIW77977.1 - 0.00051 19.3 0.0 0.00083 18.6 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EIW77977.1 - 0.0034 16.8 0.0 0.0069 15.8 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EIW77977.1 - 0.012 15.3 0.1 0.031 14.0 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EIW77977.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.5 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) MOSC_N PF03476.11 EIW77978.1 - 2.4e-18 65.9 0.1 6.4e-18 64.5 0.0 1.7 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EIW77978.1 - 3.2e-05 23.4 0.0 0.00037 19.9 0.0 2.2 1 1 0 1 1 1 1 MOSC domain SnoaL_2 PF12680.2 EIW77979.1 - 0.011 16.0 0.0 0.015 15.6 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain GST_N_3 PF13417.1 EIW77980.1 - 6.1e-10 39.1 0.0 1.4e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW77980.1 - 0.0005 20.2 0.0 0.001 19.1 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW77980.1 - 0.0014 18.4 0.1 0.0049 16.7 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW77980.1 - 0.0056 16.6 0.0 0.012 15.6 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW77980.1 - 0.0071 16.3 0.0 0.018 15.0 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EIW77980.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin DUF4395 PF14340.1 EIW77980.1 - 0.064 13.3 0.1 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) RhoGEF PF00621.15 EIW77982.1 - 5.8e-21 75.1 0.1 9.7e-21 74.4 0.1 1.3 1 0 0 1 1 1 1 RhoGEF domain TPR_11 PF13414.1 EIW77983.1 - 1.4e-54 181.6 1.0 1.9e-13 49.8 0.0 7.2 4 3 5 9 9 9 7 TPR repeat TPR_1 PF00515.23 EIW77983.1 - 7.1e-41 136.1 0.0 0.00012 21.4 0.0 10.4 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.12 EIW77983.1 - 2.8e-38 126.7 0.2 0.00026 20.6 0.0 9.8 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 EIW77983.1 - 5.8e-28 96.9 1.0 2.4e-06 28.0 0.0 6.8 6 1 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.1 EIW77983.1 - 7e-22 75.7 0.1 3.6e-05 23.6 0.0 8.8 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_12 PF13424.1 EIW77983.1 - 1.2e-21 76.4 6.6 0.0014 18.5 0.0 6.9 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.1 EIW77983.1 - 6e-20 69.9 2.0 0.00014 22.1 0.0 8.7 4 2 3 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.1 EIW77983.1 - 1.2e-16 59.1 1.7 0.21 11.4 0.0 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 EIW77983.1 - 1.8e-15 57.0 7.1 0.0002 21.6 0.0 5.5 4 1 1 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIW77983.1 - 2.1e-14 52.1 0.0 0.088 12.6 0.0 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_9 PF13371.1 EIW77983.1 - 3.5e-11 42.7 4.8 0.0059 16.4 0.0 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EIW77983.1 - 1.2e-09 38.1 3.9 0.00076 19.5 0.1 4.6 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EIW77983.1 - 1.5e-08 34.5 7.2 0.36 11.3 0.0 7.9 9 0 0 9 9 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 EIW77983.1 - 0.0023 17.0 0.0 0.0023 17.0 0.0 3.0 4 1 0 4 4 4 1 Tetratricopeptide repeat DUF3856 PF12968.2 EIW77983.1 - 0.0024 17.6 0.7 9.4 6.0 0.0 4.4 4 1 1 5 5 5 0 Domain of Unknown Function (DUF3856) PDCD2_C PF04194.8 EIW77983.1 - 0.013 15.0 0.3 1 8.9 0.0 2.4 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain Apc5 PF12862.2 EIW77983.1 - 0.036 13.8 5.8 1.6 8.5 0.0 4.0 5 1 0 5 5 4 0 Anaphase-promoting complex subunit 5 Peptidase_M9_N PF08453.5 EIW77983.1 - 0.049 12.9 1.3 0.24 10.7 0.1 2.6 3 1 1 4 4 4 0 Peptidase family M9 N-terminal TPR_20 PF14561.1 EIW77983.1 - 0.44 10.6 0.0 0.44 10.6 0.0 5.4 6 2 2 8 8 8 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EIW77983.1 - 0.83 8.9 7.9 5 6.4 0.0 4.1 5 0 0 5 5 5 0 SHNi-TPR Enkurin PF13864.1 EIW77983.1 - 2.6 8.2 5.8 0.45 10.7 0.3 2.5 3 1 0 3 3 2 0 Calmodulin-binding Nucleos_tra2_C PF07662.8 EIW77984.1 - 1.6e-65 220.4 3.0 1.6e-65 220.4 2.1 2.2 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EIW77984.1 - 2e-12 47.2 4.3 2e-12 47.2 3.0 4.1 3 1 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus p450 PF00067.17 EIW77985.1 - 1.3e-70 238.2 0.0 1.5e-70 238.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ChaC PF04752.7 EIW77986.1 - 1.3e-44 152.3 0.0 1.5e-43 148.7 0.0 1.9 1 1 0 1 1 1 1 ChaC-like protein DUF4038 PF13204.1 EIW77986.1 - 0.096 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) Diphthamide_syn PF01866.12 EIW77988.1 - 1.1e-69 234.9 0.0 1.7e-69 234.4 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein EOS1 PF12326.3 EIW77989.1 - 5.7e-12 45.5 4.7 1.6e-09 37.5 0.5 2.3 1 1 0 2 2 2 2 N-glycosylation protein Glyco_hydro_18 PF00704.23 EIW77991.1 - 3.6e-13 49.6 2.7 4.8e-13 49.2 1.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_transf_25 PF01755.12 EIW77992.1 - 1.4e-13 50.9 2.6 1.8e-05 24.4 0.5 3.1 2 1 0 3 3 3 3 Glycosyltransferase family 25 (LPS biosynthesis protein) Abhydrolase_3 PF07859.8 EIW77993.1 - 3.3e-14 52.9 0.4 2.6e-13 50.0 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EIW77993.1 - 3.9e-06 25.8 1.5 1.9e-05 23.5 1.0 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EIW77993.1 - 3.9e-05 23.4 0.0 6.7e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EIW77993.1 - 0.00048 19.0 0.0 0.00072 18.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 EIW77993.1 - 0.013 14.7 0.0 0.39 9.8 0.0 2.3 2 1 0 2 2 2 0 Prolyl oligopeptidase family Asp PF00026.18 EIW77995.1 - 1.4e-09 37.6 0.5 1.5e-09 37.5 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Glyco_hydro_48 PF02011.10 EIW77997.1 - 0.031 12.4 0.0 0.041 12.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 48 CD99L2 PF12301.3 EIW77998.1 - 0.1 12.2 5.2 0.21 11.2 3.6 1.5 1 0 0 1 1 1 0 CD99 antigen like protein 2 WTF PF03303.8 EIW77998.1 - 1.4 8.2 3.2 2.4 7.4 2.2 1.3 1 0 0 1 1 1 0 WTF protein Zip PF02535.17 EIW78000.1 - 2.2e-44 151.7 42.7 9.3e-30 103.7 20.5 3.4 2 1 0 2 2 2 2 ZIP Zinc transporter OCD_Mu_crystall PF02423.10 EIW78001.1 - 1.8e-36 125.5 0.7 1.8e-36 125.5 0.5 2.2 2 0 0 2 2 2 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EIW78001.1 - 0.00049 20.2 0.0 0.0012 18.9 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF2919 PF11143.3 EIW78002.1 - 0.0083 15.9 1.2 0.014 15.2 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2919) NUDIX_2 PF13869.1 EIW78003.1 - 8.8e-85 282.7 0.0 1e-84 282.5 0.0 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase Sulfate_transp PF00916.15 EIW78004.1 - 7.2e-41 140.0 5.4 7.4e-41 139.9 2.2 2.1 1 1 1 2 2 2 1 Sulfate transporter family cNMP_binding PF00027.24 EIW78004.1 - 2.9e-12 46.2 0.0 5.3e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 EIW78004.1 - 2.4e-08 33.4 0.1 5.3e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EIW78004.1 - 0.0057 16.6 0.8 0.0057 16.6 0.5 2.2 2 0 0 2 2 2 1 STAS domain Nexin_C PF08628.7 EIW78005.1 - 0.12 12.4 0.0 0.72 9.9 0.0 2.2 2 0 0 2 2 2 0 Sorting nexin C terminal TPR_16 PF13432.1 EIW78006.1 - 1e-09 38.7 12.8 0.00083 19.9 0.1 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIW78006.1 - 3.5e-09 36.4 17.0 0.18 12.5 0.0 8.3 6 2 2 8 8 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 EIW78006.1 - 5.1e-09 35.6 11.1 0.0007 19.2 0.0 5.0 6 0 0 6 6 6 3 TPR repeat TPR_19 PF14559.1 EIW78006.1 - 5e-08 33.1 6.7 0.022 15.1 0.1 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIW78006.1 - 1.3e-07 31.0 17.5 0.012 15.4 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIW78006.1 - 4.1e-06 26.5 2.0 0.17 12.1 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Apc3 PF12895.2 EIW78006.1 - 0.00038 20.5 0.1 0.093 12.8 0.0 3.6 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EIW78006.1 - 0.0028 17.3 9.3 0.16 11.8 0.0 5.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIW78006.1 - 0.036 13.9 14.1 2 8.4 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIW78006.1 - 0.056 13.0 0.0 0.056 13.0 0.0 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 EIW78006.1 - 0.24 11.9 16.3 8.3 7.1 0.0 6.1 6 0 0 6 6 4 0 Tetratricopeptide repeat ChAPs PF09295.5 EIW78006.1 - 0.29 9.8 0.1 0.54 8.9 0.0 1.4 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.1 EIW78006.1 - 4.8 7.8 9.4 87 3.9 0.0 5.9 7 0 0 7 7 6 0 Tetratricopeptide repeat FAP PF07174.6 EIW78010.1 - 9.2 5.4 18.2 12 5.1 12.6 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Glyco_hydro_18 PF00704.23 EIW78011.1 - 5.4e-13 49.1 2.6 6.8e-13 48.7 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Aldo_ket_red PF00248.16 EIW78012.1 - 5e-52 176.4 0.0 5.6e-52 176.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family COesterase PF00135.23 EIW78013.1 - 1.9e-93 314.0 2.4 4.2e-93 312.8 1.7 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW78013.1 - 9e-07 28.6 0.2 3.8e-06 26.6 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIW78013.1 - 0.0056 15.9 0.1 0.0099 15.1 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Glyco_transf_20 PF00982.16 EIW78015.1 - 5.9e-14 51.3 0.2 3.7e-12 45.4 0.2 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 20 Sec7_N PF12783.2 EIW78018.1 - 1.9e-35 121.7 1.1 1.4e-34 118.9 0.6 2.5 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EIW78018.1 - 8.5e-06 25.2 0.1 0.00015 21.2 0.0 3.1 3 0 0 3 3 3 1 Domain of unknown function (DUF1981) zf-C3HC4_3 PF13920.1 EIW78019.1 - 1.4e-07 31.0 6.2 2.4e-07 30.3 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW78019.1 - 3.7e-07 29.6 11.9 6.2e-07 28.9 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW78019.1 - 5.3e-07 29.3 11.9 9.3e-07 28.5 8.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIW78019.1 - 7e-07 29.1 11.8 1.2e-06 28.3 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EIW78019.1 - 8.7e-06 25.7 7.5 1.7e-05 24.7 5.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EIW78019.1 - 0.00062 19.4 11.1 0.001 18.7 7.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EIW78019.1 - 0.06 13.1 3.8 0.13 12.1 2.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EIW78019.1 - 0.35 10.7 10.3 0.75 9.7 7.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EIW78019.1 - 0.95 9.2 7.3 1.8 8.3 5.1 1.5 1 0 0 1 1 1 0 RING-type zinc-finger zf-P11 PF03854.9 EIW78019.1 - 2 7.9 5.7 4 6.9 3.9 1.4 1 0 0 1 1 1 0 P-11 zinc finger Homeobox PF00046.24 EIW78020.1 - 1.3e-14 53.5 1.9 2.5e-14 52.6 1.3 1.5 1 0 0 1 1 1 1 Homeobox domain TerB-C PF15615.1 EIW78020.1 - 0.035 14.3 0.5 0.064 13.5 0.4 1.4 1 0 0 1 1 1 0 TerB-C domain Homeobox_KN PF05920.6 EIW78020.1 - 0.072 12.7 0.1 0.072 12.7 0.1 2.2 2 0 0 2 2 2 0 Homeobox KN domain Bromodomain PF00439.20 EIW78021.1 - 8.4e-22 76.8 0.0 2.2e-21 75.5 0.0 1.8 1 0 0 1 1 1 1 Bromodomain DNA_mis_repair PF01119.14 EIW78023.1 - 7e-19 67.4 0.1 1.9e-18 66.0 0.1 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EIW78023.1 - 1.8e-13 50.3 0.1 3e-13 49.6 0.1 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EIW78023.1 - 3.4e-13 49.3 0.3 7.7e-13 48.1 0.1 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 EIW78024.1 - 2e-22 79.3 0.1 8.5e-22 77.3 0.1 1.8 2 0 0 2 2 2 1 MutL C terminal dimerisation domain FmdA_AmdA PF03069.10 EIW78025.1 - 1.4e-53 181.9 0.1 6.5e-29 100.7 0.1 2.5 1 1 1 2 2 2 2 Acetamidase/Formamidase family G-alpha PF00503.15 EIW78026.1 - 1.6e-111 372.7 0.0 1.9e-111 372.5 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIW78026.1 - 9.2e-13 47.7 0.1 3.3e-08 32.9 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 EIW78026.1 - 0.00097 18.6 0.0 0.0026 17.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain DAP3 PF10236.4 EIW78026.1 - 0.039 12.8 0.0 0.063 12.2 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Gtr1_RagA PF04670.7 EIW78026.1 - 0.066 12.3 0.1 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region DUF815 PF05673.8 EIW78026.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 EIW78026.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Pyr_redox PF00070.22 EIW78028.1 - 7.8e-12 45.4 0.0 1.4e-10 41.4 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW78028.1 - 1.1e-11 44.9 0.0 1.5e-05 24.9 0.0 3.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW78028.1 - 0.00023 20.1 0.0 0.22 10.3 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIW78028.1 - 0.00073 19.6 0.5 1 9.3 0.3 3.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW78028.1 - 0.02 13.8 0.0 0.12 11.3 0.0 2.1 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) Peptidase_S9 PF00326.16 EIW78028.1 - 0.022 13.9 0.0 0.04 13.1 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family ApbA PF02558.11 EIW78028.1 - 0.054 12.9 0.1 9.9 5.5 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 EIW78028.1 - 0.079 11.5 0.1 18 3.7 0.0 2.9 2 1 0 3 3 3 0 Tryptophan halogenase AMP-binding PF00501.23 EIW78030.1 - 2.4e-77 260.0 0.1 4.2e-77 259.3 0.1 1.3 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIW78030.1 - 3.1e-07 31.2 0.0 2.9e-06 28.1 0.0 2.5 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DIM1 PF02966.11 EIW78031.1 - 8.8e-69 229.1 0.0 9.9e-69 228.9 0.0 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 EIW78031.1 - 0.00033 20.2 0.0 0.00044 19.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EIW78031.1 - 0.0089 16.1 0.2 0.014 15.5 0.1 1.3 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EIW78031.1 - 0.1 12.6 0.1 0.2 11.6 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin-like Thioredox_DsbH PF03190.10 EIW78031.1 - 0.11 12.1 0.2 0.21 11.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Glyco_hydro_28 PF00295.12 EIW78033.1 - 1.2e-51 175.6 14.9 1.5e-51 175.3 10.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EIW78033.1 - 0.00096 18.9 32.3 0.14 11.9 18.8 3.5 1 1 1 2 2 2 2 Right handed beta helix region adh_short PF00106.20 EIW78034.1 - 6.3e-26 91.2 0.5 6.2e-25 88.0 0.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW78034.1 - 6.9e-16 58.7 0.2 1.7e-15 57.4 0.1 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW78034.1 - 9.4e-11 41.6 0.3 1.8e-10 40.7 0.2 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW78034.1 - 0.00011 21.7 0.4 0.00038 19.9 0.3 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EIW78034.1 - 0.0012 18.5 0.1 0.0019 17.8 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EIW78034.1 - 0.0041 16.0 0.0 0.0069 15.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Pyr_redox PF00070.22 EIW78034.1 - 0.032 14.6 0.0 0.18 12.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EIW78034.1 - 0.061 12.8 0.1 0.11 12.0 0.1 1.5 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF1776 PF08643.5 EIW78034.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF3488 PF11992.3 EIW78035.1 - 0.04 12.5 4.1 0.049 12.2 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) zf-DHHC PF01529.15 EIW78035.1 - 2.2 7.6 4.2 3.7 6.9 2.9 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase SnoaL_2 PF12680.2 EIW78036.1 - 0.0079 16.5 0.0 0.011 16.1 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Nramp PF01566.13 EIW78041.1 - 0.0018 17.1 3.1 0.0024 16.7 2.1 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein DUF3488 PF11992.3 EIW78041.1 - 0.74 8.3 7.5 1.1 7.8 5.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Piwi PF02171.12 EIW78043.1 - 1.1e-80 270.8 0.1 1.5e-80 270.4 0.1 1.1 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EIW78043.1 - 1.4e-16 59.9 0.0 2.9e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EIW78043.1 - 6.3e-13 47.8 0.0 1.5e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) p450 PF00067.17 EIW78045.1 - 1e-55 189.1 0.0 1.3e-54 185.4 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 Cauli_VI PF01693.11 EIW78050.1 - 5.3e-08 32.7 0.1 8e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin BTB PF00651.26 EIW78055.1 - 3.6e-05 23.7 0.0 0.0001 22.2 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain PAT1 PF09770.4 EIW78057.1 - 6.9 4.7 9.7 7.6 4.6 6.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PCNA_N PF00705.13 EIW78058.1 - 5e-51 171.4 3.2 1.4e-50 170.0 1.7 2.0 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EIW78058.1 - 1.5e-39 134.8 0.0 1.2e-20 73.7 0.0 2.5 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EIW78058.1 - 2e-07 30.4 0.0 4.5e-07 29.2 0.0 1.6 2 0 0 2 2 2 1 Rad9 Nop14 PF04147.7 EIW78058.1 - 0.04 11.8 35.9 0.057 11.3 24.9 1.2 1 0 0 1 1 1 0 Nop14-like family Hus1 PF04005.7 EIW78058.1 - 0.051 12.5 4.9 0.96 8.3 0.0 3.2 2 1 2 4 4 4 0 Hus1-like protein SAPS PF04499.10 EIW78058.1 - 1.1 7.7 10.8 3.6 6.1 7.8 1.6 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein NACHT PF05729.7 EIW78059.1 - 3.9e-11 42.8 0.0 1e-10 41.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW78059.1 - 8e-08 32.4 0.1 2.1e-07 31.1 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW78059.1 - 4.7e-05 23.5 0.0 0.00012 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EIW78059.1 - 0.00015 21.4 0.1 0.00031 20.4 0.1 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase PRK PF00485.13 EIW78059.1 - 0.0004 20.0 0.0 0.00092 18.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 EIW78059.1 - 0.00053 20.1 0.0 0.00099 19.2 0.0 1.4 1 0 0 1 1 1 1 RNA helicase Arch_ATPase PF01637.13 EIW78059.1 - 0.0038 16.9 0.0 0.008 15.9 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase AAA_17 PF13207.1 EIW78059.1 - 0.0056 17.5 0.0 0.015 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIW78059.1 - 0.0064 16.8 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIW78059.1 - 0.0089 16.3 0.0 0.018 15.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EIW78059.1 - 0.031 13.7 0.1 0.075 12.5 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MobB PF03205.9 EIW78059.1 - 0.032 13.9 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EIW78059.1 - 0.033 12.9 0.1 0.064 12.0 0.0 1.3 1 0 0 1 1 1 0 ArgK protein Zeta_toxin PF06414.7 EIW78059.1 - 0.038 13.0 0.0 0.078 12.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NTPase_1 PF03266.10 EIW78059.1 - 0.044 13.4 0.0 0.072 12.8 0.0 1.3 1 0 0 1 1 1 0 NTPase DUF258 PF03193.11 EIW78059.1 - 0.046 12.9 0.0 0.079 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 CbiA PF01656.18 EIW78059.1 - 0.047 13.0 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain T2SE PF00437.15 EIW78059.1 - 0.048 12.5 0.0 0.073 11.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 EIW78059.1 - 0.058 13.2 0.1 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EIW78059.1 - 0.062 12.2 0.0 0.087 11.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EIW78059.1 - 0.15 11.7 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain UPF0079 PF02367.12 EIW78059.1 - 0.17 11.5 0.1 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_10 PF12846.2 EIW78059.1 - 0.19 11.1 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain NB-ARC PF00931.17 EIW78059.1 - 0.32 9.8 0.0 0.5 9.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain TatD_DNase PF01026.16 EIW78060.1 - 2.4e-39 135.0 0.0 6.9e-37 127.0 0.0 2.1 1 1 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 EIW78060.1 - 8e-06 25.6 0.1 1.5e-05 24.6 0.1 1.5 1 1 0 1 1 1 1 Amidohydrolase DUF3571 PF12095.3 EIW78060.1 - 0.075 13.2 0.1 0.48 10.6 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3571) UxaC PF02614.9 EIW78060.1 - 0.11 11.0 0.5 0.22 10.0 0.4 1.4 1 0 0 1 1 1 0 Glucuronate isomerase PBP-Tp47_c PF14888.1 EIW78061.1 - 0.0022 17.6 0.1 0.006 16.2 0.1 1.7 1 0 0 1 1 1 1 Penicillin-binding protein Tp47 domain C PMT_C PF11647.3 EIW78061.1 - 0.014 14.9 0.0 0.045 13.3 0.0 1.9 1 0 0 1 1 1 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 Myosin_tail_1 PF01576.14 EIW78061.1 - 0.39 8.3 24.9 0.61 7.7 17.2 1.2 1 0 0 1 1 1 0 Myosin tail CENP-F_leu_zip PF10473.4 EIW78061.1 - 2.8 7.7 23.8 0.078 12.8 0.8 3.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 zf-HC5HC2H_2 PF13832.1 EIW78062.1 - 0.0012 18.7 0.9 0.0044 16.9 0.6 2.0 1 0 0 1 1 1 1 PHD-zinc-finger like domain Daxx PF03344.10 EIW78062.1 - 0.0038 15.8 2.6 0.0047 15.4 1.8 1.1 1 0 0 1 1 1 1 Daxx Family zf-HC5HC2H PF13771.1 EIW78062.1 - 0.042 13.9 1.0 0.19 11.9 0.7 2.1 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-Di19 PF05605.7 EIW78062.1 - 0.072 13.2 0.5 0.072 13.2 0.4 2.2 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EIW78065.1 - 0.0015 18.7 4.1 0.0035 17.5 1.0 2.8 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW78065.1 - 0.027 14.8 4.8 0.032 14.5 1.0 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger DUF2890 PF11081.3 EIW78066.1 - 0.2 11.7 2.2 0.31 11.0 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Sugar_tr PF00083.19 EIW78067.1 - 6.3e-110 367.8 25.4 7.3e-110 367.6 17.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW78067.1 - 9.1e-22 77.2 39.6 1.9e-21 76.2 22.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DDE_1 PF03184.14 EIW78068.1 - 7.3e-10 38.3 0.0 8.1e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIW78069.1 - 1.1e-08 34.4 0.0 1.2e-08 34.3 0.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease FRG2 PF15315.1 EIW78070.1 - 0.2 11.6 8.0 0.37 10.7 5.5 1.3 1 0 0 1 1 1 0 Facioscapulohumeral muscular dystrophy candidate 2 Zn_clus PF00172.13 EIW78070.1 - 2 8.4 10.2 5.4 7.0 7.1 1.8 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Tet_JBP PF12851.2 EIW78071.1 - 1.6e-12 47.0 0.0 1.9e-12 46.8 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily 2OG-FeII_Oxy_3 PF13640.1 EIW78071.1 - 0.00041 20.8 0.0 0.00071 20.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-B_box PF00643.19 EIW78072.1 - 5 7.0 6.8 0.64 9.9 1.5 2.0 2 0 0 2 2 2 0 B-box zinc finger Cyclin PF08613.6 EIW78074.1 - 1.1e-06 29.1 0.0 1.4e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EIW78074.1 - 0.003 17.1 0.0 0.0046 16.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain MgpC PF05220.7 EIW78077.1 - 0.13 11.3 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 MgpC protein precursor Gln-synt_C PF00120.19 EIW78078.1 - 2e-53 181.2 0.0 2.5e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Saccharop_dh PF03435.13 EIW78079.1 - 1.7e-111 372.9 0.0 2e-111 372.7 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EIW78079.1 - 9.3e-06 25.7 0.1 2.2e-05 24.5 0.1 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EIW78079.1 - 0.0026 17.8 0.5 0.0047 16.9 0.4 1.4 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EIW78079.1 - 0.0028 17.6 0.5 0.0047 16.9 0.4 1.3 1 0 0 1 1 1 1 TrkA-N domain GFO_IDH_MocA PF01408.17 EIW78079.1 - 0.0043 17.5 0.1 0.0075 16.7 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EIW78079.1 - 0.052 13.8 0.2 0.089 13.0 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain HD PF01966.17 EIW78080.1 - 1.4e-05 25.0 0.3 2.3e-05 24.4 0.2 1.3 1 0 0 1 1 1 1 HD domain Limkain-b1 PF11608.3 EIW78080.1 - 0.0075 15.9 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 Limkain b1 Phytoreo_Pns PF05451.6 EIW78082.1 - 0.12 10.9 0.0 0.18 10.4 0.0 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns10/11 F-box-like PF12937.2 EIW78085.1 - 2.9e-08 33.3 0.0 7.4e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW78085.1 - 0.03 13.9 0.0 0.077 12.6 0.0 1.6 1 0 0 1 1 1 0 F-box domain PAPA-1 PF04795.7 EIW78085.1 - 0.51 11.0 5.3 0.83 10.3 3.7 1.3 1 0 0 1 1 1 0 PAPA-1-like conserved region Prenyltrans PF00432.16 EIW78087.1 - 5.6e-33 112.1 15.4 7.6e-08 31.7 0.1 6.1 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EIW78087.1 - 2.8e-21 76.0 0.0 8.8e-19 67.9 0.0 3.2 3 0 0 3 3 3 1 Prenyltransferase-like Prenyltrans_1 PF13243.1 EIW78087.1 - 8.2e-08 32.2 0.0 0.00011 22.1 0.0 2.6 2 1 2 4 4 4 3 Prenyltransferase-like Saccharop_dh PF03435.13 EIW78088.1 - 1.4e-112 376.4 0.3 2.7e-112 375.5 0.0 1.6 2 0 0 2 2 2 1 Saccharopine dehydrogenase Spermine_synth PF01564.12 EIW78088.1 - 9.5e-91 303.0 0.0 1.7e-90 302.2 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase Shikimate_DH PF01488.15 EIW78088.1 - 3.8e-08 33.4 0.6 1.2e-06 28.6 0.1 2.8 3 1 0 3 3 2 1 Shikimate / quinate 5-dehydrogenase Methyltransf_18 PF12847.2 EIW78088.1 - 0.00012 22.6 0.0 0.0009 19.8 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain NAD_binding_10 PF13460.1 EIW78088.1 - 0.00028 20.9 0.4 0.00064 19.7 0.3 1.6 1 0 0 1 1 1 1 NADH(P)-binding Methyltransf_31 PF13847.1 EIW78088.1 - 0.00032 20.3 0.0 0.0016 18.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW78088.1 - 0.00058 20.2 0.1 0.063 13.7 0.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain GFO_IDH_MocA PF01408.17 EIW78088.1 - 0.0041 17.6 0.3 0.02 15.4 0.1 2.1 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EIW78088.1 - 0.0046 17.3 0.5 0.0096 16.3 0.3 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EIW78088.1 - 0.012 15.9 0.5 0.026 14.8 0.1 1.8 2 0 0 2 2 1 0 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 EIW78088.1 - 0.012 15.5 2.1 0.029 14.3 0.2 2.3 2 0 0 2 2 2 0 TrkA-N domain F420_oxidored PF03807.12 EIW78088.1 - 0.026 14.9 0.1 0.068 13.6 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MTS PF05175.9 EIW78088.1 - 0.039 13.3 0.0 0.088 12.1 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.7 EIW78088.1 - 0.056 13.9 0.0 3.6 8.1 0.0 3.2 3 1 1 4 4 4 0 Methyltransferase domain DREV PF05219.7 EIW78088.1 - 0.086 11.7 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Pterin_bind PF00809.17 EIW78088.1 - 0.12 11.7 0.7 2.5 7.4 0.5 2.3 1 1 0 1 1 1 0 Pterin binding enzyme NAD_binding_7 PF13241.1 EIW78088.1 - 0.14 12.4 0.2 12 6.2 0.1 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding DUF2325 PF10087.4 EIW78088.1 - 0.19 11.5 0.6 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) HMG_box PF00505.14 EIW78089.1 - 0.017 15.3 2.1 0.086 13.1 1.4 2.0 1 1 0 1 1 1 0 HMG (high mobility group) box F-box-like PF12937.2 EIW78091.1 - 3e-06 26.8 0.0 0.045 13.4 0.0 2.8 2 0 0 2 2 2 2 F-box-like NmrA PF05368.8 EIW78092.1 - 3.7e-14 52.5 0.0 1.4e-13 50.6 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIW78092.1 - 3.4e-09 36.9 0.0 5.8e-09 36.2 0.0 1.4 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EIW78092.1 - 1.5e-06 27.8 0.0 2.2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIW78092.1 - 0.0035 16.2 0.0 0.0058 15.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EIW78092.1 - 0.019 14.9 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.7 EIW78092.1 - 0.031 13.1 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein KR PF08659.5 EIW78092.1 - 0.063 12.9 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.14 EIW78092.1 - 0.1 11.2 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family SRP54_N PF02881.14 EIW78092.1 - 0.11 12.6 0.1 1.9 8.6 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain Polysacc_synt_2 PF02719.10 EIW78092.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 EIW78092.1 - 0.14 12.5 0.0 0.28 11.4 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Mito_carr PF00153.22 EIW78093.1 - 9.7e-22 76.4 5.9 2.9e-09 36.5 0.1 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein VIT1 PF01988.14 EIW78093.1 - 0.65 9.4 8.3 0.16 11.4 0.7 2.7 2 1 0 3 3 3 0 VIT family Glyco_hydro_16 PF00722.16 EIW78094.1 - 3.9e-06 26.2 0.1 8.5e-06 25.1 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 WW PF00397.21 EIW78094.1 - 0.23 11.3 4.7 0.52 10.2 0.0 2.8 2 0 0 2 2 2 0 WW domain DUF1517 PF07466.6 EIW78095.1 - 0.0078 15.2 8.6 0.041 12.8 5.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1517) Glyco_hydro_28 PF00295.12 EIW78097.1 - 1e-55 188.9 18.8 1.3e-55 188.6 13.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EIW78097.1 - 0.00024 20.8 42.6 0.0067 16.1 25.6 3.5 1 1 1 2 2 2 1 Right handed beta helix region DUF1565 PF07602.6 EIW78097.1 - 0.0013 17.9 15.7 0.0014 17.7 9.2 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1565) Flavodoxin_NdrI PF07972.6 EIW78097.1 - 0.1 12.4 5.0 18 5.2 0.1 3.9 3 1 1 4 4 4 0 NrdI Flavodoxin like Glyco_hydro_28 PF00295.12 EIW78098.1 - 1e-54 185.6 16.2 1.3e-54 185.3 11.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EIW78098.1 - 0.00021 21.1 22.4 0.00021 21.1 15.5 2.8 1 1 2 3 3 3 2 Right handed beta helix region Hydrophobin PF01185.13 EIW78099.1 - 6.2e-16 58.6 11.9 8.5e-16 58.1 8.3 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Viral_DNA_bi PF02236.12 EIW78100.1 - 0.11 12.6 0.2 0.21 11.7 0.2 1.4 1 0 0 1 1 1 0 Viral DNA-binding protein, all alpha domain DUF4218 PF13960.1 EIW78102.1 - 0.00086 18.7 0.2 0.0016 17.8 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) HMG_box PF00505.14 EIW78103.1 - 0.00083 19.5 3.3 0.00083 19.5 2.3 2.6 3 0 0 3 3 3 1 HMG (high mobility group) box ubiquitin PF00240.18 EIW78103.1 - 0.0041 16.4 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family HMG_box_2 PF09011.5 EIW78103.1 - 0.0094 16.3 1.7 0.0094 16.3 1.1 1.7 2 0 0 2 2 2 1 HMG-box domain Herpes_LP PF03363.8 EIW78104.1 - 0.0047 16.5 0.5 0.0076 15.8 0.4 1.3 1 0 0 1 1 1 1 Herpesvirus leader protein HMG_box PF00505.14 EIW78108.1 - 3.2e-12 46.5 0.5 5.7e-12 45.7 0.3 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIW78108.1 - 0.0037 17.5 0.2 0.0073 16.6 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain DUF1864 PF08933.6 EIW78108.1 - 0.077 11.5 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) Sporozoite_P67 PF05642.6 EIW78108.1 - 0.35 8.6 6.0 0.53 8.0 4.1 1.4 1 0 0 1 1 1 0 Sporozoite P67 surface antigen START PF01852.14 EIW78110.1 - 0.039 13.2 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 START domain Acetyltransf_1 PF00583.19 EIW78112.1 - 4.2e-15 55.5 0.0 6.6e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EIW78112.1 - 2.6e-08 33.4 0.2 4.3e-08 32.8 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EIW78112.1 - 2.3e-07 30.8 0.0 3.8e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIW78112.1 - 7.8e-06 26.0 0.1 1.6e-05 25.0 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIW78112.1 - 0.00041 20.3 0.0 0.0019 18.1 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIW78112.1 - 0.0006 19.9 0.0 0.001 19.2 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIW78112.1 - 0.006 16.4 0.0 0.02 14.7 0.0 1.9 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EIW78112.1 - 0.013 15.1 0.1 0.028 14.1 0.0 1.5 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase FAD_binding_4 PF01565.18 EIW78113.1 - 1.3e-21 76.5 1.6 2.3e-21 75.7 1.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EIW78113.1 - 1.4e-06 28.0 0.1 2.9e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like RNase_P_p30 PF01876.11 EIW78115.1 - 1.2e-28 99.2 0.0 6.2e-28 96.9 0.0 1.9 2 0 0 2 2 2 1 RNase P subunit p30 Cellulase PF00150.13 EIW78117.1 - 3.9e-14 52.5 0.0 8.2e-14 51.4 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) AraC_binding_2 PF14525.1 EIW78120.1 - 0.018 14.6 0.4 0.029 13.9 0.3 1.3 1 0 0 1 1 1 0 AraC-binding-like domain F-box-like PF12937.2 EIW78121.1 - 0.0096 15.6 0.3 0.026 14.2 0.2 1.8 1 0 0 1 1 1 1 F-box-like Pterin_4a PF01329.14 EIW78121.1 - 0.085 12.6 0.0 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 Pterin 4 alpha carbinolamine dehydratase LRR_4 PF12799.2 EIW78123.1 - 8.4e-05 22.0 1.8 6.3 6.5 0.0 4.6 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EIW78123.1 - 0.00022 20.8 0.9 0.00062 19.4 0.7 1.7 1 0 0 1 1 1 1 F-box-like HhH-GPD PF00730.20 EIW78124.1 - 2.8e-12 46.8 0.0 4.5e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF937 PF06078.6 EIW78124.1 - 0.033 14.4 0.0 0.05 13.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF937) HHH PF00633.18 EIW78124.1 - 0.081 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif LRR_4 PF12799.2 EIW78125.1 - 0.0034 16.9 0.4 1.7 8.3 0.0 4.3 3 2 1 4 4 4 1 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EIW78125.1 - 0.065 12.9 0.0 0.2 11.3 0.0 1.9 1 0 0 1 1 1 0 F-box-like Dimer_Tnp_hAT PF05699.9 EIW78126.1 - 4.3e-08 32.6 0.0 4.4e-08 32.6 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region LT-IIB PF06453.6 EIW78126.1 - 0.066 12.8 0.1 0.071 12.7 0.1 1.0 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) LRR_4 PF12799.2 EIW78127.1 - 0.12 12.0 0.3 0.91 9.2 0.1 2.5 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) PLDc_N PF13396.1 EIW78128.1 - 0.42 10.3 3.4 0.79 9.4 0.4 2.7 2 0 0 2 2 2 0 Phospholipase_D-nuclease N-terminal COesterase PF00135.23 EIW78129.1 - 7.6e-182 605.7 0.0 6.7e-91 305.6 0.2 2.2 2 0 0 2 2 2 2 Carboxylesterase family DNA_pol_A PF00476.15 EIW78129.1 - 4.6e-91 305.2 0.0 6.6e-91 304.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A Abhydrolase_3 PF07859.8 EIW78129.1 - 9.3e-18 64.5 3.6 5.2e-08 32.7 0.1 4.3 3 2 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW78129.1 - 0.0015 18.2 3.5 0.66 9.7 0.1 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family RSF PF14876.1 EIW78129.1 - 1.3 7.7 0.0 2 7.1 0.0 1.2 1 0 0 1 1 1 0 Respiratory growth transcriptional regulator DUF2424 PF10340.4 EIW78129.1 - 2.6 6.5 0.1 86 1.5 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2424) WBS28 PF15164.1 EIW78131.1 - 0.11 11.6 5.8 0.15 11.1 4.1 1.2 1 0 0 1 1 1 0 Williams-Beuren syndrome chromosomal region 28 protein homologue Aminotran_1_2 PF00155.16 EIW78133.1 - 5.5e-34 117.6 0.0 7e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SHMT PF00464.14 EIW78133.1 - 0.099 10.9 0.0 0.13 10.6 0.0 1.2 1 0 0 1 1 1 0 Serine hydroxymethyltransferase HMG_box PF00505.14 EIW78136.1 - 4.8e-12 45.9 0.2 9.3e-12 45.0 0.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIW78136.1 - 0.00017 21.8 0.6 0.00035 20.8 0.1 1.8 2 0 0 2 2 2 1 HMG-box domain HMG_box_5 PF14887.1 EIW78136.1 - 0.1 12.3 0.3 0.2 11.4 0.2 1.4 1 0 0 1 1 1 0 HMG (high mobility group) box 5 LRR_4 PF12799.2 EIW78139.1 - 0.00075 19.0 0.3 1.1 8.9 0.1 3.5 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) COesterase PF00135.23 EIW78140.1 - 5.8e-91 305.8 0.3 7.4e-91 305.4 0.2 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW78140.1 - 5.5e-09 35.9 1.4 7.1e-08 32.2 1.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW78140.1 - 0.052 13.2 0.3 0.11 12.2 0.2 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family NmrA PF05368.8 EIW78141.1 - 1.4e-20 73.5 0.0 1.8e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIW78141.1 - 5.1e-08 33.1 0.1 5.8e-08 32.9 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EIW78141.1 - 3e-05 23.1 0.1 3.7e-05 22.8 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 EIW78141.1 - 0.00056 19.6 0.0 0.00092 18.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW78141.1 - 0.0065 15.9 0.0 0.01 15.3 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EIW78141.1 - 0.0093 15.8 0.1 0.017 15.0 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase CPSase_L_chain PF00289.17 EIW78141.1 - 0.0095 16.0 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain NAD_binding_4 PF07993.7 EIW78141.1 - 0.013 14.4 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.10 EIW78141.1 - 0.031 13.1 0.0 0.04 12.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EIW78141.1 - 0.033 14.2 0.0 0.051 13.6 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.15 EIW78141.1 - 0.042 13.7 0.5 0.88 9.4 0.1 2.5 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus F-box-like PF12937.2 EIW78142.1 - 3.1e-06 26.7 0.3 0.0011 18.6 0.1 2.8 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 EIW78142.1 - 0.00025 20.5 2.1 0.13 11.9 0.4 3.0 2 0 0 2 2 2 2 F-box domain Hydrophobin_2 PF06766.6 EIW78142.1 - 0.1 12.2 0.3 11 5.8 0.0 2.8 2 0 0 2 2 2 0 Fungal hydrophobin WD40 PF00400.27 EIW78143.1 - 5.2e-21 73.6 11.9 4.5e-07 29.5 0.3 6.1 5 1 1 6 6 6 4 WD domain, G-beta repeat BBS2_N PF14781.1 EIW78143.1 - 0.047 13.3 0.0 1.6 8.3 0.0 2.9 4 0 0 4 4 4 0 Ciliary BBSome complex subunit 2, N-terminal Lipase_3 PF01764.20 EIW78144.1 - 4.2e-24 84.7 0.0 6.3e-24 84.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EIW78144.1 - 0.002 18.0 0.1 0.0042 16.9 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EIW78144.1 - 0.0037 16.8 0.1 0.0054 16.3 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein UPF0227 PF05728.7 EIW78144.1 - 0.0042 16.8 0.0 0.0065 16.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.2 EIW78144.1 - 0.022 14.5 0.0 0.044 13.5 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW78144.1 - 0.024 14.1 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cutinase PF01083.17 EIW78144.1 - 0.095 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Cutinase Apo-CIII PF05778.7 EIW78144.1 - 0.098 12.0 0.2 2.5 7.5 0.0 2.6 2 0 0 2 2 2 0 Apolipoprotein CIII (Apo-CIII) Peptidase_C14 PF00656.17 EIW78145.1 - 5.4e-11 42.6 0.0 5.9e-10 39.2 0.0 2.0 1 1 1 2 2 2 1 Caspase domain Peptidase_C13 PF01650.13 EIW78145.1 - 3.4e-05 23.2 0.1 0.03 13.6 0.0 2.1 1 1 1 2 2 2 2 Peptidase C13 family F-box-like PF12937.2 EIW78146.1 - 3.8e-05 23.3 1.2 0.00012 21.7 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIW78146.1 - 0.042 13.5 0.6 2.1 8.0 0.0 3.2 3 0 0 3 3 3 0 F-box domain HMG_box_2 PF09011.5 EIW78149.1 - 3.7e-09 36.8 3.6 8.8e-09 35.6 2.5 1.6 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.14 EIW78149.1 - 4.4e-09 36.4 9.8 1.3e-07 31.7 6.8 2.3 1 1 0 1 1 1 1 HMG (high mobility group) box AA_permease_2 PF13520.1 EIW78151.1 - 1.7e-75 254.1 47.9 2.2e-75 253.8 33.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIW78152.1 - 4.1e-78 262.8 39.7 5.4e-78 262.4 27.5 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIW78152.1 - 4.3e-17 61.6 31.6 6.4e-17 61.0 21.9 1.2 1 0 0 1 1 1 1 Amino acid permease Transp_cyt_pur PF02133.10 EIW78153.1 - 8.5e-101 337.6 34.6 9.7e-101 337.4 24.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin AA_permease_2 PF13520.1 EIW78154.1 - 3.1e-74 250.0 39.8 4e-74 249.6 27.6 1.2 1 0 0 1 1 1 1 Amino acid permease NmrA PF05368.8 EIW78155.1 - 4.8e-18 65.2 0.0 6.5e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIW78155.1 - 1.7e-06 28.1 0.2 2.9e-06 27.4 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EIW78155.1 - 2.4e-06 26.7 0.1 3.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EIW78155.1 - 0.0001 21.8 0.1 0.00021 20.8 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EIW78155.1 - 0.011 15.5 0.3 0.66 9.9 0.1 2.3 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.5 EIW78155.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.10 EIW78155.1 - 0.013 14.4 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 EIW78155.1 - 0.027 14.4 0.1 0.045 13.6 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.7 EIW78155.1 - 0.048 12.5 0.0 0.1 11.5 0.0 1.6 2 0 0 2 2 2 0 Male sterility protein Shikimate_DH PF01488.15 EIW78155.1 - 0.16 12.1 0.1 0.26 11.3 0.1 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lipase_3 PF01764.20 EIW78156.1 - 4.6e-20 71.6 0.0 7e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EIW78156.1 - 0.008 15.7 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EIW78156.1 - 0.0097 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW78156.1 - 0.085 12.6 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW78156.1 - 0.12 11.9 0.2 0.33 10.4 0.1 1.7 1 1 1 2 2 2 0 alpha/beta hydrolase fold COesterase PF00135.23 EIW78157.1 - 1.5e-92 311.0 0.1 2e-92 310.6 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW78157.1 - 2.4e-08 33.8 1.9 3.3e-07 30.1 1.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIW78157.1 - 0.07 12.3 0.1 0.15 11.2 0.1 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Lipase_3 PF01764.20 EIW78158.1 - 2.2e-21 75.9 0.0 2.9e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EIW78158.1 - 0.014 15.3 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW78158.1 - 0.073 12.8 0.0 0.13 11.9 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 EIW78158.1 - 0.12 11.6 0.0 0.25 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 EIW78158.1 - 0.16 11.4 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein tRNA-synt_1d PF00750.14 EIW78159.1 - 3.7e-80 269.3 0.6 4.8e-80 269.0 0.4 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EIW78159.1 - 2.8e-18 65.9 0.0 6.5e-18 64.8 0.0 1.7 1 0 0 1 1 1 1 DALR anticodon binding domain Isy1 PF06246.7 EIW78160.1 - 1.5e-80 270.2 2.4 3.2e-80 269.2 1.7 1.5 1 1 0 1 1 1 1 Isy1-like splicing family P22_Tail-4 PF11650.3 EIW78160.1 - 0.044 13.3 0.2 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 P22 tail accessory factor UPF0220 PF05255.6 EIW78161.1 - 1.7e-52 176.9 0.0 2.2e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) NmrA PF05368.8 EIW78162.1 - 8.5e-18 64.4 0.0 1.1e-17 64.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIW78162.1 - 1e-06 28.9 0.2 1.2e-06 28.6 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EIW78162.1 - 3.2e-06 26.3 0.5 4.2e-06 25.9 0.3 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EIW78162.1 - 0.0014 18.1 0.2 0.0024 17.3 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EIW78162.1 - 0.0049 15.7 0.0 0.0077 15.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GARS_N PF02844.10 EIW78162.1 - 0.009 16.4 0.2 0.018 15.5 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain adh_short PF00106.20 EIW78162.1 - 0.013 15.4 2.1 0.019 14.8 1.4 1.3 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_4 PF07993.7 EIW78162.1 - 0.031 13.1 0.0 0.044 12.7 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein GFO_IDH_MocA PF01408.17 EIW78162.1 - 0.069 13.6 0.1 0.12 12.8 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold CPSase_L_chain PF00289.17 EIW78162.1 - 0.1 12.7 0.1 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Shikimate_DH PF01488.15 EIW78162.1 - 0.12 12.4 0.1 0.19 11.8 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.14 EIW78162.1 - 0.17 10.5 0.2 0.62 8.7 0.2 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family SKG6 PF08693.5 EIW78163.1 - 0.0031 16.7 2.7 0.0068 15.6 1.9 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EIW78163.1 - 0.012 15.0 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) TMEM154 PF15102.1 EIW78163.1 - 0.07 12.8 0.3 0.1 12.3 0.2 1.2 1 0 0 1 1 1 0 TMEM154 protein family SP_C-Propep PF08999.5 EIW78163.1 - 0.092 12.2 0.1 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Adeno_E3_CR2 PF02439.10 EIW78163.1 - 0.096 12.2 0.5 0.18 11.3 0.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 CD34_antigen PF06365.7 EIW78163.1 - 0.11 12.1 0.0 0.16 11.6 0.0 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF202 PF02656.10 EIW78163.1 - 0.11 12.6 0.1 0.19 11.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) DUF4231 PF14015.1 EIW78166.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Peptidase_C14 PF00656.17 EIW78167.1 - 5.9e-10 39.2 0.0 6.1e-09 35.9 0.0 2.2 2 1 0 2 2 2 1 Caspase domain DUF3550 PF12070.3 EIW78167.1 - 0.067 11.9 0.0 0.086 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3550/UPF0682) SKG6 PF08693.5 EIW78168.1 - 0.00021 20.5 0.4 0.00055 19.1 0.3 1.8 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EphA2_TM PF14575.1 EIW78168.1 - 0.018 15.4 0.0 0.035 14.5 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain HMG_box PF00505.14 EIW78169.1 - 1.1e-12 47.9 0.8 2.1e-12 47.0 0.1 1.9 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIW78169.1 - 0.00011 22.5 0.1 0.00045 20.5 0.0 2.0 2 0 0 2 2 2 1 HMG-box domain Aldo_ket_red PF00248.16 EIW78172.1 - 4.8e-51 173.2 0.0 5.7e-51 173.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DEAD PF00270.24 EIW78173.1 - 7.6e-19 67.8 0.0 1.5e-18 66.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EIW78173.1 - 3e-08 33.7 0.0 3.2e-07 30.3 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EIW78173.1 - 9.6e-06 25.3 0.0 2.2e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 EIW78173.1 - 0.21 10.7 0.0 0.42 9.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Transket_pyr PF02779.19 EIW78174.1 - 4.9e-61 205.3 0.0 7.2e-61 204.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EIW78174.1 - 3.4e-39 134.3 0.0 4.9e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component HAD PF12710.2 EIW78175.1 - 9.1e-12 45.5 0.0 2e-11 44.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EIW78175.1 - 0.0013 18.1 0.1 0.0026 17.1 0.0 1.5 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD_2 PF13419.1 EIW78175.1 - 0.002 18.3 0.1 0.034 14.3 0.0 2.8 3 2 1 4 4 4 1 Haloacid dehalogenase-like hydrolase DUF4154 PF13689.1 EIW78175.1 - 0.0046 16.5 0.0 0.074 12.6 0.0 2.4 1 1 0 2 2 2 1 Domain of unknown function (DUF4154) Hydrolase PF00702.21 EIW78175.1 - 0.0065 16.9 4.4 0.042 14.2 0.5 3.3 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EIW78175.1 - 0.02 14.0 1.0 2.3 7.3 0.0 3.1 2 1 0 2 2 2 0 Putative Phosphatase DUF2975 PF11188.3 EIW78176.1 - 1.5 8.5 23.7 0.026 14.2 4.1 3.2 2 2 1 3 3 3 0 Protein of unknown function (DUF2975) Ribosomal_S6e PF01092.14 EIW78177.1 - 3e-62 207.9 0.3 5.4e-62 207.0 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S6e Ribosomal_S13_N PF08069.7 EIW78178.1 - 3.6e-30 103.5 0.5 7.3e-30 102.5 0.2 1.7 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EIW78178.1 - 7.2e-23 80.1 0.1 9.5e-23 79.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 EIW78178.1 - 0.017 14.7 0.0 0.025 14.2 0.0 1.5 1 1 0 1 1 1 0 'Paired box' domain IBR PF01485.16 EIW78179.1 - 1.5e-08 34.3 34.8 1.4e-05 24.8 6.4 3.5 3 0 0 3 3 3 3 IBR domain zf-H2C2_2 PF13465.1 EIW78179.1 - 0.68 10.3 0.1 0.68 10.3 0.1 4.4 4 0 0 4 4 4 0 Zinc-finger double domain PIN_4 PF13638.1 EIW78179.1 - 0.72 9.9 3.5 13 5.8 0.0 2.4 2 0 0 2 2 2 0 PIN domain HemY_N PF07219.8 EIW78179.1 - 6.3 6.4 6.4 17 5.0 3.7 2.2 2 0 0 2 2 2 0 HemY protein N-terminus DUF706 PF05153.10 EIW78180.1 - 2.5e-126 420.1 0.3 3e-126 419.9 0.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF706) Sec34 PF04136.10 EIW78180.1 - 0.079 12.6 0.0 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 Sec34-like family HD PF01966.17 EIW78180.1 - 0.15 12.0 0.1 1 9.3 0.0 2.1 2 0 0 2 2 2 0 HD domain HSP70 PF00012.15 EIW78181.1 - 5.1e-69 232.7 0.0 8.5e-40 136.2 0.0 3.0 2 1 1 3 3 3 3 Hsp70 protein MreB_Mbl PF06723.8 EIW78181.1 - 1.8e-07 30.1 0.0 0.0071 14.9 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EIW78181.1 - 0.081 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain SMC_N PF02463.14 EIW78182.1 - 2.8e-63 213.1 0.0 5.9e-63 212.0 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EIW78182.1 - 4.1e-31 107.4 0.3 1.4e-30 105.6 0.2 2.0 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EIW78182.1 - 3.4e-15 56.7 0.0 1.7e-06 28.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EIW78182.1 - 1.6e-07 30.7 0.0 3.3e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ERM PF00769.14 EIW78182.1 - 1.4e-06 28.0 26.1 1.4e-06 28.0 18.1 5.0 2 2 3 5 5 5 1 Ezrin/radixin/moesin family AAA_23 PF13476.1 EIW78182.1 - 1.7e-06 28.5 25.3 1.7e-06 28.5 17.5 5.9 2 2 1 3 3 1 1 AAA domain AAA_15 PF13175.1 EIW78182.1 - 0.00031 19.9 4.6 0.18 10.7 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain SbcCD_C PF13558.1 EIW78182.1 - 0.0011 18.8 0.0 0.005 16.7 0.0 2.3 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Filament PF00038.16 EIW78182.1 - 0.0017 17.8 17.4 0.0017 17.8 12.0 5.7 4 1 2 6 6 5 3 Intermediate filament protein Tropomyosin PF00261.15 EIW78182.1 - 0.0033 16.5 19.9 0.0033 16.5 13.8 6.4 3 2 2 6 6 5 3 Tropomyosin Reo_sigmaC PF04582.7 EIW78182.1 - 0.069 12.3 18.5 0.56 9.3 1.0 4.6 5 0 0 5 5 5 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 EIW78182.1 - 0.1 12.9 0.0 0.1 12.9 0.0 4.8 4 3 0 4 4 2 0 ABC transporter RbsD_FucU PF05025.8 EIW78182.1 - 0.45 10.8 0.0 0.45 10.8 0.0 3.9 4 1 1 5 5 4 0 RbsD / FucU transport protein family Spc7 PF08317.6 EIW78182.1 - 0.52 8.9 71.4 0.0061 15.2 2.3 5.2 3 2 1 5 5 5 0 Spc7 kinetochore protein NPV_P10 PF05531.7 EIW78182.1 - 7.4 6.9 18.4 3.1 8.1 0.6 5.5 5 1 1 6 6 5 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.1 EIW78182.1 - 7.8 4.8 72.3 0.15 10.4 0.4 6.7 4 2 3 7 7 7 0 AAA domain Laminin_II PF06009.7 EIW78182.1 - 7.9 6.2 48.7 0.024 14.3 4.2 6.9 6 1 1 7 7 7 0 Laminin Domain II MFS_1 PF07690.11 EIW78183.1 - 2e-18 66.2 28.6 2e-18 66.2 19.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EIW78183.1 - 8.8e-07 27.6 4.2 8.8e-07 27.6 2.9 2.5 2 1 1 3 3 3 2 MFS/sugar transport protein DUF1228 PF06779.9 EIW78183.1 - 0.11 12.4 0.2 0.11 12.4 0.1 3.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1228) adh_short PF00106.20 EIW78185.1 - 3e-25 89.0 0.1 4.2e-25 88.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW78185.1 - 1.6e-20 73.9 0.0 2.2e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW78185.1 - 1.1e-07 31.7 0.0 2.2e-07 30.6 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIW78185.1 - 4.7e-07 29.9 0.0 1.1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW78185.1 - 2.1e-05 24.1 0.1 7.7e-05 22.2 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIW78185.1 - 0.00045 19.1 0.0 0.00077 18.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.12 EIW78185.1 - 0.013 15.9 0.1 0.032 14.6 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.3 EIW78185.1 - 0.1 12.3 0.1 0.25 11.1 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase WD40 PF00400.27 EIW78187.1 - 7.8e-121 390.1 28.1 1.2e-10 40.8 0.0 13.1 13 0 0 13 13 13 13 WD domain, G-beta repeat eIF2A PF08662.6 EIW78187.1 - 3.3e-13 49.8 0.0 0.0016 18.1 0.0 5.8 3 2 3 6 6 6 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIW78187.1 - 1.6e-08 33.1 6.6 0.076 11.1 0.0 8.0 3 2 3 9 9 9 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIW78187.1 - 6.3e-07 28.4 2.2 0.22 10.2 0.0 4.5 2 2 1 3 3 3 3 Nup133 N terminal like Nbas_N PF15492.1 EIW78187.1 - 8.3e-07 28.3 3.3 3.9 6.5 0.0 7.1 5 2 4 9 9 9 2 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 EIW78187.1 - 4.7e-06 26.2 0.4 0.013 14.9 0.1 4.5 1 1 1 2 2 2 1 PQQ-like domain Coatomer_WDAD PF04053.9 EIW78187.1 - 6.2e-06 25.2 0.0 0.099 11.4 0.0 3.2 2 1 1 3 3 3 2 Coatomer WD associated region PD40 PF07676.7 EIW78187.1 - 8.7e-06 25.2 6.9 3.5 7.3 0.0 7.2 8 0 0 8 8 8 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 EIW78187.1 - 0.00076 17.8 0.3 2 6.6 0.0 4.1 2 2 1 4 4 4 1 Cytochrome D1 heme domain Gmad1 PF10647.4 EIW78187.1 - 0.0023 17.3 0.2 1.1 8.6 0.2 4.0 2 2 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain DUF3312 PF11768.3 EIW78187.1 - 0.0065 14.7 0.0 0.33 9.1 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF3312) B_lectin PF01453.19 EIW78187.1 - 0.013 15.4 0.0 0.13 12.1 0.1 2.7 2 0 0 2 2 2 0 D-mannose binding lectin Arena_nucleocap PF00843.12 EIW78187.1 - 0.075 10.9 0.0 2.9 5.6 0.0 3.3 2 1 1 3 3 3 0 Arenavirus nucleocapsid protein Apc4_WD40 PF12894.2 EIW78187.1 - 0.092 12.2 0.0 5.5 6.5 0.0 3.8 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.16 EIW78187.1 - 0.18 10.3 0.0 39 2.6 0.0 4.3 3 3 2 5 5 5 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region TFIIIC_delta PF12657.2 EIW78187.1 - 0.24 11.0 1.8 1.7 8.2 0.0 3.3 4 0 0 4 4 4 0 Transcription factor IIIC subunit delta N-term adh_short PF00106.20 EIW78190.1 - 5.1e-05 23.2 0.0 0.0018 18.2 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase WD40 PF00400.27 EIW78191.1 - 3.8e-64 210.4 26.5 1.6e-10 40.4 0.1 10.9 11 0 0 11 11 11 10 WD domain, G-beta repeat eIF2A PF08662.6 EIW78191.1 - 3.3e-12 46.5 0.0 0.0014 18.4 0.0 5.0 3 3 1 5 5 5 3 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 EIW78191.1 - 0.00018 20.9 0.1 0.1 12.0 0.0 3.3 4 0 0 4 4 4 1 Lipoprotein LpqB beta-propeller domain SGL PF08450.7 EIW78191.1 - 0.0003 20.2 0.1 0.29 10.4 0.0 3.8 2 2 3 5 5 5 1 SMP-30/Gluconolaconase/LRE-like region Nup160 PF11715.3 EIW78191.1 - 0.00093 17.4 0.2 5.1 5.1 0.0 4.4 3 1 0 4 4 4 1 Nucleoporin Nup120/160 PD40 PF07676.7 EIW78191.1 - 0.003 17.1 7.8 14 5.4 0.0 6.6 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 EIW78191.1 - 0.021 14.2 0.6 9 5.6 0.2 3.6 2 1 0 2 2 2 0 PQQ-like domain Nbas_N PF15492.1 EIW78191.1 - 0.026 13.6 0.9 15 4.6 0.0 4.3 4 2 2 6 6 6 0 Neuroblastoma-amplified sequence, N terminal DPPIV_N PF00930.16 EIW78191.1 - 0.066 11.7 0.0 4.8 5.6 0.0 3.7 4 2 2 6 6 6 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region adh_short PF00106.20 EIW78192.1 - 2.6e-28 99.0 0.2 4.5e-28 98.2 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW78192.1 - 4.8e-18 65.8 0.0 6.3e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW78192.1 - 8.4e-12 45.1 0.0 1.7e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIW78192.1 - 9.7e-08 32.2 0.2 1.9e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW78192.1 - 1.3e-07 31.3 0.0 3.8e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIW78192.1 - 0.0026 16.7 0.0 0.0041 16.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EIW78192.1 - 0.0051 15.5 0.0 0.0078 14.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Eno-Rase_NADH_b PF12242.3 EIW78192.1 - 0.0086 15.8 0.1 0.02 14.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase F420_oxidored PF03807.12 EIW78192.1 - 0.024 15.0 0.1 0.054 13.9 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent MAPEG PF01124.13 EIW78193.1 - 2.8e-16 59.2 4.5 3.4e-16 59.0 3.1 1.1 1 0 0 1 1 1 1 MAPEG family adh_short PF00106.20 EIW78195.1 - 1.2e-24 87.1 0.1 1.7e-24 86.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW78195.1 - 6.9e-19 68.5 0.0 1e-18 68.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW78195.1 - 2.7e-07 30.4 0.0 4.9e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIW78195.1 - 2.6e-06 27.5 0.1 5.4e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW78195.1 - 0.0013 18.2 0.2 0.0037 16.7 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIW78195.1 - 0.0052 15.7 0.0 0.0075 15.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain F420_oxidored PF03807.12 EIW78195.1 - 0.081 13.3 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Eno-Rase_NADH_b PF12242.3 EIW78195.1 - 0.11 12.3 0.0 0.38 10.5 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase MFS_1 PF07690.11 EIW78196.1 - 1.1e-17 63.7 44.9 5.1e-13 48.4 9.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIW78196.1 - 6.2e-08 31.4 18.6 1.7e-05 23.4 7.1 2.6 1 1 1 2 2 2 2 MFS/sugar transport protein DUF1228 PF06779.9 EIW78196.1 - 0.05 13.6 12.3 1.3 9.1 0.1 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1228) DUF3980 PF13140.1 EIW78196.1 - 0.24 11.6 2.6 0.34 11.2 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3980) WD40 PF00400.27 EIW78197.1 - 1.8e-21 75.1 13.3 4.3e-11 42.2 0.1 8.1 9 0 0 9 9 9 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW78197.1 - 8.9e-15 54.8 0.9 1.9e-06 27.5 0.2 4.5 2 1 0 4 4 4 3 PQQ-like domain PD40 PF07676.7 EIW78197.1 - 2.4e-05 23.8 8.3 8.8 6.1 0.0 7.7 9 0 0 9 9 9 2 WD40-like Beta Propeller Repeat Hira PF07569.6 EIW78197.1 - 5.7e-05 22.4 0.0 0.2 10.8 0.0 3.6 4 0 0 4 4 4 2 TUP1-like enhancer of split PQQ PF01011.16 EIW78197.1 - 0.0086 15.5 1.6 24 4.7 0.0 4.9 5 0 0 5 5 5 0 PQQ enzyme repeat PQQ_3 PF13570.1 EIW78197.1 - 0.097 12.9 2.4 8.2 6.8 0.0 4.1 4 0 0 4 4 4 0 PQQ-like domain Proteasome_A_N PF10584.4 EIW78197.1 - 3.6 6.9 8.0 38 3.7 0.0 4.5 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature MIP PF00230.15 EIW78198.1 - 1.8e-50 171.5 11.1 2.2e-50 171.2 7.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein E1-E2_ATPase PF00122.15 EIW78199.1 - 1.5e-21 76.5 0.0 4.3e-21 74.9 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EIW78199.1 - 5e-21 76.1 0.0 2.7e-20 73.6 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIW78199.1 - 3.1e-19 69.8 0.1 8.3e-19 68.4 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase OPT PF03169.10 EIW78199.1 - 5.1e-11 41.7 1.9 1.3e-10 40.3 1.3 1.8 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Hydrolase_like2 PF13246.1 EIW78199.1 - 0.00046 20.0 0.0 0.001 19.0 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EIW78199.1 - 0.05 13.1 0.0 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase WD40 PF00400.27 EIW78200.1 - 2.9e-23 80.8 35.0 1.8e-07 30.7 0.0 10.1 12 0 0 12 12 12 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW78200.1 - 4.6e-14 52.4 0.1 3.1e-05 23.5 0.0 4.5 2 1 1 3 3 3 3 PQQ-like domain PQQ PF01011.16 EIW78200.1 - 4.7e-07 29.0 0.1 0.34 10.5 0.0 5.4 6 0 0 6 6 6 2 PQQ enzyme repeat PD40 PF07676.7 EIW78200.1 - 2.9e-05 23.6 3.3 6.6 6.5 0.0 6.7 8 0 0 8 8 8 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 EIW78200.1 - 0.00079 17.8 0.0 0.064 11.5 0.0 2.8 2 1 0 2 2 2 1 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 EIW78200.1 - 0.013 14.8 4.7 0.46 9.8 0.0 4.8 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature Lactonase PF10282.4 EIW78200.1 - 0.023 13.7 0.0 0.16 10.9 0.0 2.5 3 1 0 3 3 3 0 Lactonase, 7-bladed beta-propeller Nucleoporin_N PF08801.6 EIW78200.1 - 0.026 13.2 0.0 3 6.4 0.0 3.0 3 0 0 3 3 3 0 Nup133 N terminal like DPPIV_N PF00930.16 EIW78200.1 - 0.038 12.5 0.0 1.5 7.3 0.0 3.1 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region Apc4_WD40 PF12894.2 EIW78200.1 - 0.12 11.8 0.0 0.85 9.1 0.0 2.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.1 EIW78200.1 - 0.14 12.4 10.2 13 6.2 0.0 6.1 6 1 1 7 7 7 0 PQQ-like domain Sec23_trunk PF04811.10 EIW78202.1 - 7e-75 251.5 0.0 1e-74 250.9 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EIW78202.1 - 2.7e-34 116.6 0.2 5.6e-34 115.6 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EIW78202.1 - 1.3e-28 99.3 0.1 2.5e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EIW78202.1 - 5e-17 61.1 6.4 9e-17 60.3 4.5 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EIW78202.1 - 6e-15 54.6 0.0 1.4e-13 50.3 0.0 2.4 2 0 0 2 2 2 1 Gelsolin repeat WD40 PF00400.27 EIW78203.1 - 4.1e-105 340.3 35.3 1e-12 47.3 0.0 11.1 11 0 0 11 11 11 11 WD domain, G-beta repeat eIF2A PF08662.6 EIW78203.1 - 6e-09 35.8 0.0 0.56 9.8 0.0 4.7 2 2 4 6 6 6 5 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EIW78203.1 - 7.9e-09 34.9 1.0 0.35 10.5 0.0 5.9 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EIW78203.1 - 2.8e-07 29.0 16.1 0.24 9.4 0.1 8.1 2 2 6 8 8 8 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIW78203.1 - 5.2e-05 22.1 7.2 2.4 6.7 0.0 5.7 1 1 2 6 6 6 2 Nup133 N terminal like PQQ_3 PF13570.1 EIW78203.1 - 0.00095 19.3 1.9 8.5 6.8 0.0 5.1 5 0 0 5 5 5 1 PQQ-like domain Gmad1 PF10647.4 EIW78203.1 - 0.0016 17.9 1.5 0.22 10.8 0.0 3.8 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain Coatomer_WDAD PF04053.9 EIW78203.1 - 0.0018 17.1 0.0 0.08 11.7 0.0 2.2 2 0 0 2 2 2 1 Coatomer WD associated region DUF3312 PF11768.3 EIW78203.1 - 0.005 15.1 0.2 6.4 4.8 0.0 3.5 4 1 0 4 4 4 1 Protein of unknown function (DUF3312) Proteasome_A_N PF10584.4 EIW78203.1 - 0.0066 15.7 5.6 18 4.7 0.0 6.0 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature PQQ_2 PF13360.1 EIW78203.1 - 0.019 14.4 1.3 0.36 10.2 0.3 3.2 2 1 0 2 2 2 0 PQQ-like domain TFIIIC_delta PF12657.2 EIW78203.1 - 0.11 12.2 4.7 6.5 6.4 0.0 4.2 5 0 0 5 5 5 0 Transcription factor IIIC subunit delta N-term Peptidase_S9_N PF02897.10 EIW78203.1 - 0.13 10.8 0.0 12 4.2 0.0 3.0 3 0 0 3 3 3 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Med15 PF09606.5 EIW78204.1 - 0.0038 15.5 0.9 0.0041 15.3 0.6 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Sugar_tr PF00083.19 EIW78205.1 - 2.3e-20 72.6 19.2 1.5e-19 69.9 13.3 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW78205.1 - 5e-19 68.2 44.9 4.3e-12 45.4 18.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Apc4_WD40 PF12894.2 EIW78206.1 - 0.0027 17.1 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.1 EIW78206.1 - 0.0045 16.4 0.0 0.0045 16.4 0.0 1.1 1 0 0 1 1 1 1 PQQ-like domain WD40 PF00400.27 EIW78206.1 - 0.0076 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 WD domain, G-beta repeat ADH_zinc_N PF00107.21 EIW78207.1 - 9e-23 80.2 0.0 1.6e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW78207.1 - 6.7e-06 27.0 0.0 1.8e-05 25.6 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EIW78207.1 - 0.013 15.4 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding ApbA PF02558.11 EIW78207.1 - 0.09 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EIW78207.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Sporozoite_P67 PF05642.6 EIW78208.1 - 0.083 10.7 5.8 0.12 10.1 4.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PLDc PF00614.17 EIW78208.1 - 0.16 11.8 0.5 0.33 10.8 0.4 1.5 1 0 0 1 1 1 0 Phospholipase D Active site motif NOA36 PF06524.7 EIW78208.1 - 1.6 7.9 4.9 2.5 7.2 3.4 1.2 1 0 0 1 1 1 0 NOA36 protein FAD_binding_3 PF01494.14 EIW78209.1 - 2.7e-70 237.2 0.0 4.5e-70 236.4 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EIW78209.1 - 0.00013 22.0 0.3 0.00061 19.9 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW78209.1 - 0.0021 17.2 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EIW78209.1 - 0.0071 16.7 0.2 1.1 9.7 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW78209.1 - 0.013 15.4 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIW78209.1 - 0.029 13.2 0.0 0.061 12.1 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EIW78209.1 - 0.033 12.6 0.4 0.084 11.3 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein DAO PF01266.19 EIW78209.1 - 0.042 12.7 1.2 0.22 10.3 0.0 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIW78209.1 - 0.091 12.6 1.5 0.22 11.3 1.1 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NMD3 PF04981.8 EIW78210.1 - 1.9e-73 246.4 0.4 2.5e-73 246.1 0.3 1.1 1 0 0 1 1 1 1 NMD3 family Rpr2 PF04032.11 EIW78210.1 - 0.03 14.1 1.6 3.9 7.4 0.1 2.7 1 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DZR PF12773.2 EIW78210.1 - 0.11 12.3 7.9 0.066 13.0 2.2 2.6 1 1 1 2 2 2 0 Double zinc ribbon NinF PF05810.7 EIW78210.1 - 0.19 11.5 1.9 0.4 10.5 0.5 2.1 2 0 0 2 2 2 0 NinF protein GFA PF04828.9 EIW78210.1 - 0.4 10.6 3.9 6.2 6.8 0.1 3.3 2 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme zf-C3HC4_3 PF13920.1 EIW78210.1 - 1.6 8.4 5.5 0.35 10.5 0.3 2.4 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DASH_Dam1 PF08653.5 EIW78211.1 - 1e-12 47.6 0.1 1.8e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 DASH complex subunit Dam1 Apc4 PF12896.2 EIW78211.1 - 0.022 14.0 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 DUF4519 PF15012.1 EIW78211.1 - 0.12 12.2 2.7 0.23 11.4 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) RNA_pol_N PF01194.12 EIW78212.1 - 2.2e-31 107.6 0.5 2.6e-31 107.4 0.4 1.0 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Chordopox_RPO7 PF05864.7 EIW78212.1 - 0.033 14.2 0.1 0.04 13.9 0.1 1.2 1 0 0 1 1 1 0 Chordopoxvirus DNA-directed RNA polymerase 7 kDa polypeptide (RPO7) F-box-like PF12937.2 EIW78213.1 - 0.013 15.1 0.0 0.043 13.5 0.0 1.9 1 1 0 1 1 1 0 F-box-like F-box-like PF12937.2 EIW78214.1 - 0.017 14.8 1.5 0.044 13.5 0.1 2.4 2 1 0 2 2 2 0 F-box-like Collagen PF01391.13 EIW78214.1 - 0.59 9.7 14.3 0.96 9.0 9.9 1.2 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) MIP PF00230.15 EIW78215.1 - 6.9e-44 149.9 11.1 8e-44 149.7 7.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein ADH_zinc_N PF00107.21 EIW78216.1 - 3.9e-24 84.6 0.1 5.8e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW78216.1 - 1.3e-06 29.2 0.0 6.7e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 EIW78216.1 - 0.016 15.2 0.0 0.041 13.8 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain NMO PF03060.10 EIW78216.1 - 0.041 13.0 0.0 0.086 11.9 0.0 1.5 2 0 0 2 2 2 0 Nitronate monooxygenase ApbA PF02558.11 EIW78216.1 - 0.059 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 EIW78216.1 - 0.079 12.9 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding PIP5K PF01504.13 EIW78218.1 - 4.9e-86 287.9 0.0 6.8e-86 287.4 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Peptidase_C50 PF03568.12 EIW78219.1 - 1.2e-87 294.1 0.0 8.2e-87 291.3 0.0 2.0 1 1 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 EIW78219.1 - 3e-06 27.0 17.7 6.8e-06 25.9 1.2 6.0 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIW78219.1 - 0.00098 18.6 3.7 5.9 6.6 0.0 5.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIW78219.1 - 0.0061 16.1 1.3 0.0061 16.1 0.9 5.6 6 0 0 6 6 6 1 TPR repeat TPR_10 PF13374.1 EIW78219.1 - 0.0061 16.4 12.2 0.17 11.8 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EIW78219.1 - 0.015 15.4 0.3 3 8.0 0.0 3.8 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EIW78219.1 - 0.036 14.7 36.8 0.14 12.8 6.8 7.3 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIW78219.1 - 0.15 12.0 21.8 6.2 6.9 0.0 7.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIW78219.1 - 6.3 7.7 26.0 12 6.8 2.2 7.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Cnd1 PF12717.2 EIW78221.1 - 4.4e-59 199.3 9.9 1.1e-55 188.2 0.3 4.1 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 EIW78221.1 - 8.4e-41 139.4 0.0 8.4e-41 139.4 0.0 4.0 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 EIW78221.1 - 1.3e-07 31.8 8.2 0.011 15.9 0.0 5.3 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.17 EIW78221.1 - 8.8e-05 22.2 3.8 18 5.7 0.0 6.0 6 0 0 6 6 6 1 HEAT repeat DUF2435 PF10363.4 EIW78221.1 - 0.0037 17.1 5.0 11 5.9 0.1 4.5 3 2 1 4 4 4 2 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 EIW78221.1 - 0.0099 16.3 2.2 3.5 8.2 0.0 4.8 4 1 1 5 5 5 1 HEAT-like repeat YtzH PF14165.1 EIW78221.1 - 0.48 10.6 5.1 0.74 10.0 0.0 3.5 3 0 0 3 3 3 0 YtzH-like protein MFS_1 PF07690.11 EIW78222.1 - 8.3e-47 159.5 15.2 8.3e-47 159.5 10.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 EIW78222.1 - 0.0035 15.4 6.7 0.0069 14.5 1.8 2.6 3 0 0 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family DUF2207 PF09972.4 EIW78222.1 - 2.1 6.8 6.0 0.31 9.5 0.4 2.2 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) 2TM PF13239.1 EIW78222.1 - 6.8 6.8 11.0 0.66 10.0 0.2 3.8 5 0 0 5 5 5 0 2TM domain SKN1 PF03935.10 EIW78223.1 - 5.7e-06 24.7 0.0 8.4e-06 24.2 0.0 1.2 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Cnd3 PF12719.2 EIW78225.1 - 1.7e-79 266.9 1.3 4.1e-78 262.3 0.2 2.9 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EIW78225.1 - 5.4e-08 33.0 7.2 9.5e-05 22.6 0.2 4.5 4 0 0 4 4 4 3 HEAT repeats HEAT PF02985.17 EIW78225.1 - 3e-06 26.8 1.4 0.16 12.1 0.0 4.6 3 0 0 3 3 3 3 HEAT repeat HEAT_EZ PF13513.1 EIW78225.1 - 0.0037 17.6 4.1 1.8 9.1 0.1 4.1 3 0 0 3 3 3 2 HEAT-like repeat zf-MYND PF01753.13 EIW78226.1 - 1.8e-09 37.3 11.2 3.9e-09 36.2 7.7 1.6 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EIW78226.1 - 0.039 13.8 5.6 1.4 8.8 3.7 2.3 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 PAD_porph PF04371.10 EIW78226.1 - 0.096 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Porphyromonas-type peptidyl-arginine deiminase DUF2267 PF10025.4 EIW78226.1 - 0.11 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) E1-E2_ATPase PF00122.15 EIW78229.1 - 1.8e-58 197.3 0.3 1.8e-58 197.3 0.2 2.5 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EIW78229.1 - 1.1e-22 81.5 0.4 2.2e-22 80.5 0.3 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIW78229.1 - 7.3e-13 49.1 0.1 2.2e-12 47.5 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIW78229.1 - 8.3e-12 44.4 0.1 2.2e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIW78229.1 - 0.00026 20.6 0.0 0.0006 19.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIW78229.1 - 0.16 11.9 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit UDP-g_GGTase PF06427.6 EIW78230.1 - 2.7e-47 160.8 0.0 5.1e-47 159.8 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EIW78230.1 - 1.5e-07 31.0 0.0 2.5e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 MFS_1 PF07690.11 EIW78231.1 - 3.4e-52 177.3 13.8 4.7e-52 176.8 9.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW78231.1 - 4e-14 52.0 22.0 2.3e-11 42.9 3.3 3.1 3 0 0 3 3 3 3 Sugar (and other) transporter MFS_2 PF13347.1 EIW78231.1 - 3e-06 25.9 5.1 3e-06 25.9 3.5 3.1 3 2 0 3 3 3 1 MFS/sugar transport protein OATP PF03137.15 EIW78231.1 - 0.022 12.8 6.7 0.038 12.0 3.1 2.4 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 EIW78232.1 - 3.3e-51 174.0 15.8 5.1e-51 173.4 11.0 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 EIW78232.1 - 0.00025 19.2 5.8 0.0011 17.1 1.6 2.6 2 1 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family ApbA PF02558.11 EIW78233.1 - 0.0071 15.7 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Herpes_gE PF02480.11 EIW78233.1 - 0.021 13.1 0.0 0.024 12.8 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Phage_HK97_TLTM PF06120.6 EIW78233.1 - 0.24 10.7 1.6 0.35 10.1 1.1 1.2 1 0 0 1 1 1 0 Tail length tape measure protein p450 PF00067.17 EIW78234.1 - 1.8e-58 198.2 0.0 2.2e-58 197.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EIW78235.1 - 2.4e-52 178.1 0.0 3.5e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain WD40 PF00400.27 EIW78236.1 - 4e-35 118.4 22.5 2.9e-10 39.5 0.0 10.6 10 0 0 10 10 10 8 WD domain, G-beta repeat eIF2A PF08662.6 EIW78236.1 - 1.1e-11 44.8 0.0 3.9e-06 26.7 0.0 4.0 2 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EIW78236.1 - 1.1e-11 44.6 3.9 0.0035 16.8 0.0 4.9 2 2 2 4 4 4 4 PQQ-like domain DPPIV_N PF00930.16 EIW78236.1 - 7.1e-06 24.8 0.0 0.12 10.9 0.0 4.5 4 0 0 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 EIW78236.1 - 1.4e-05 24.5 7.3 0.19 11.3 0.0 7.3 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 EIW78236.1 - 0.00053 18.3 0.1 0.85 7.8 0.0 4.2 3 2 2 5 5 5 2 Cytochrome D1 heme domain Apc4_WD40 PF12894.2 EIW78236.1 - 0.0033 16.8 0.0 0.023 14.1 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Hira PF07569.6 EIW78236.1 - 0.008 15.4 0.0 2.8 7.1 0.0 4.1 4 0 0 4 4 4 1 TUP1-like enhancer of split TruB_C PF09142.6 EIW78236.1 - 0.0096 15.5 0.2 3.5 7.3 0.0 4.8 7 0 0 7 7 7 1 tRNA Pseudouridine synthase II, C terminal Nucleoporin_N PF08801.6 EIW78236.1 - 0.02 13.6 0.0 1.2 7.8 0.0 3.3 4 0 0 4 4 4 0 Nup133 N terminal like PQQ PF01011.16 EIW78236.1 - 0.045 13.3 6.4 8.9 6.0 0.0 6.2 7 0 0 7 7 7 0 PQQ enzyme repeat Fork_head PF00250.13 EIW78237.1 - 1.1e-07 31.7 0.0 2.1e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Fork head domain Securin PF04856.8 EIW78237.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Securin sister-chromatid separation inhibitor Pkinase PF00069.20 EIW78238.1 - 1.3e-71 240.7 0.0 2.1e-71 240.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW78238.1 - 5.7e-43 146.8 0.0 9e-43 146.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EIW78238.1 - 5.7e-31 106.3 0.9 2.2e-19 69.2 0.1 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.1 EIW78238.1 - 2.8e-08 33.0 0.0 6.7e-08 31.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like DUF4520 PF15016.1 EIW78238.1 - 0.0018 17.8 0.1 0.015 14.9 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4520) zf-RING_2 PF13639.1 EIW78239.1 - 4.1e-13 48.9 5.2 7.3e-13 48.1 3.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIW78239.1 - 2.4e-10 40.3 0.6 4.7e-10 39.4 0.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EIW78239.1 - 6.3e-07 28.9 3.1 1e-06 28.2 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW78239.1 - 1.4e-06 27.9 4.0 2.3e-06 27.2 2.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIW78239.1 - 2.7e-06 26.9 4.3 5e-06 26.0 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW78239.1 - 7.6e-06 25.8 4.6 1.4e-05 25.0 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIW78239.1 - 0.00075 19.2 3.8 0.0015 18.3 2.1 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EIW78239.1 - 0.023 14.6 4.1 0.058 13.3 2.8 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 EIW78239.1 - 0.15 11.7 3.8 0.25 11.0 2.6 1.4 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 EIW78239.1 - 0.82 9.4 4.5 0.23 11.2 0.7 1.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 RINGv PF12906.2 EIW78239.1 - 0.87 9.6 5.8 1.6 8.8 4.1 1.4 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 EIW78239.1 - 1.1 8.8 2.8 2.1 8.0 1.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain C1_1 PF00130.17 EIW78239.1 - 2.8 7.7 5.6 1.1 8.9 2.3 1.5 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) p450 PF00067.17 EIW78240.1 - 7.3e-79 265.4 0.0 1.1e-78 264.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Fork_head PF00250.13 EIW78241.1 - 1.4e-05 25.0 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Fork head domain FAD_binding_3 PF01494.14 EIW78242.1 - 1.8e-75 254.2 0.0 2.3e-75 253.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIW78242.1 - 1.9e-06 27.0 0.8 3.3e-05 22.9 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW78242.1 - 5.1e-06 26.8 1.8 0.0052 17.1 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW78242.1 - 8.9e-06 25.6 0.1 2.4e-05 24.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIW78242.1 - 1.1e-05 24.6 0.0 2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.9 EIW78242.1 - 1.1e-05 24.2 1.7 4.4e-05 22.2 0.1 2.0 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.9 EIW78242.1 - 7.8e-05 21.3 0.9 0.00033 19.2 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EIW78242.1 - 0.00017 20.8 1.2 0.0005 19.2 0.8 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIW78242.1 - 0.00022 21.1 0.2 0.00067 19.5 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW78242.1 - 0.00041 19.3 1.7 0.00041 19.3 1.2 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EIW78242.1 - 0.00058 19.9 1.0 0.0023 18.0 0.2 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EIW78242.1 - 0.0068 16.6 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding GIDA PF01134.17 EIW78242.1 - 0.027 13.3 0.1 0.047 12.5 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EIW78242.1 - 0.039 13.7 0.2 0.072 12.8 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EIW78242.1 - 0.055 12.3 0.6 0.1 11.5 0.4 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EIW78243.1 - 5.9e-75 252.5 0.0 8.7e-75 251.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIW78243.1 - 1.5e-09 37.2 0.3 3.9e-05 22.7 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW78243.1 - 8.6e-06 26.0 1.0 0.022 15.1 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW78243.1 - 1.1e-05 24.0 1.0 9.6e-05 21.0 0.7 2.0 1 1 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 EIW78243.1 - 5.5e-05 21.9 1.7 0.0023 16.6 0.0 2.1 1 1 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.1 EIW78243.1 - 0.00013 21.8 0.1 0.00042 20.2 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIW78243.1 - 0.00023 21.3 0.2 0.0008 19.5 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW78243.1 - 0.00033 19.8 0.1 0.00063 18.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EIW78243.1 - 0.0015 17.6 0.6 0.014 14.4 0.2 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIW78243.1 - 0.0022 17.9 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW78243.1 - 0.0053 15.6 2.3 0.0084 14.9 0.4 1.9 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EIW78243.1 - 0.039 12.8 0.3 0.072 11.9 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 EIW78243.1 - 0.048 12.5 0.2 0.54 9.0 0.1 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_7 PF13241.1 EIW78243.1 - 0.063 13.5 0.1 0.17 12.1 0.0 1.8 2 0 0 2 2 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EIW78243.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Glyco_hydro_114 PF03537.8 EIW78245.1 - 2e-18 65.9 0.1 5.4e-18 64.5 0.1 1.7 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 adh_short PF00106.20 EIW78246.1 - 2.9e-21 76.1 0.1 4.1e-21 75.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW78246.1 - 3.8e-09 36.4 0.1 5e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW78246.1 - 0.0023 17.3 0.2 0.0085 15.5 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIW78246.1 - 0.011 14.4 0.0 0.014 14.0 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIW78246.1 - 0.03 14.3 0.2 0.059 13.3 0.1 1.8 1 1 0 1 1 1 0 NADH(P)-binding PsbY PF06298.6 EIW78247.1 - 0.17 11.4 1.1 0.29 10.6 0.7 1.4 1 0 0 1 1 1 0 Photosystem II protein Y (PsbY) Thaumatin PF00314.12 EIW78248.1 - 1.1e-63 214.5 9.9 1.3e-63 214.3 6.9 1.0 1 0 0 1 1 1 1 Thaumatin family F-box PF00646.28 EIW78249.1 - 0.00043 19.8 0.3 0.0014 18.2 0.2 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW78249.1 - 0.017 14.8 0.3 0.051 13.3 0.1 2.0 2 0 0 2 2 2 0 F-box-like Ribosomal_S7e PF01251.13 EIW78249.1 - 0.1 12.0 0.1 0.17 11.3 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein S7e Topoisom_bac PF01131.15 EIW78249.1 - 0.2 10.4 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 DNA topoisomerase DUF1662 PF07878.6 EIW78250.1 - 0.031 13.9 0.0 0.091 12.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1662) p450 PF00067.17 EIW78252.1 - 2.3e-69 234.0 0.0 4.1e-69 233.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 SKN1 PF03935.10 EIW78253.1 - 2.2e-181 603.4 0.8 2.8e-181 603.0 0.5 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) CBS PF00571.23 EIW78254.1 - 2.3e-16 59.2 4.4 9.6e-06 25.2 0.1 5.0 4 1 0 4 4 4 4 CBS domain SR-25 PF10500.4 EIW78254.1 - 3.8 6.9 9.0 6.2 6.2 6.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein tRNA-synt_2c PF01411.14 EIW78255.1 - 8.3e-07 27.6 0.0 1.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EIW78255.1 - 0.00029 20.6 0.0 0.00093 19.0 0.0 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain adh_short PF00106.20 EIW78256.1 - 5.3e-26 91.5 0.5 8.2e-26 90.8 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW78256.1 - 1.4e-17 64.3 0.0 1.9e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW78256.1 - 4.8e-09 36.1 0.1 9.7e-09 35.1 0.0 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIW78256.1 - 5.5e-07 29.7 0.2 1.2e-06 28.6 0.1 1.6 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW78256.1 - 0.0013 18.2 0.3 0.0044 16.4 0.2 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EIW78256.1 - 0.0036 17.0 0.0 0.022 14.5 0.0 2.3 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 EIW78256.1 - 0.0074 15.2 0.1 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Saccharop_dh PF03435.13 EIW78256.1 - 0.019 13.9 0.3 0.029 13.3 0.0 1.4 2 0 0 2 2 2 0 Saccharopine dehydrogenase SKN1 PF03935.10 EIW78258.1 - 1e-184 614.3 3.0 1.3e-184 614.0 2.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Lge1 PF11488.3 EIW78259.1 - 0.0007 19.7 3.7 0.00085 19.4 2.5 1.3 1 0 0 1 1 1 1 Transcriptional regulatory protein LGE1 DUF904 PF06005.7 EIW78259.1 - 0.0027 17.9 4.1 0.0027 17.9 2.8 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF904) Saw1 PF11561.3 EIW78259.1 - 0.0053 16.1 1.7 0.0059 16.0 1.2 1.0 1 0 0 1 1 1 1 Single strand annealing-weakened 1 DUF3450 PF11932.3 EIW78259.1 - 0.011 15.0 6.5 0.013 14.8 4.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) DivIC PF04977.10 EIW78259.1 - 0.013 14.9 4.1 0.013 14.9 2.9 2.0 1 1 1 2 2 2 0 Septum formation initiator DUF3958 PF13125.1 EIW78259.1 - 0.014 15.3 2.5 0.016 15.0 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3958) bZIP_1 PF00170.16 EIW78259.1 - 0.037 13.9 7.3 0.15 12.0 2.1 2.3 2 0 0 2 2 2 0 bZIP transcription factor Apt1 PF10351.4 EIW78259.1 - 0.045 12.6 5.0 0.052 12.4 3.4 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain DUF2122 PF09895.4 EIW78259.1 - 0.055 13.6 0.2 0.068 13.3 0.1 1.1 1 0 0 1 1 1 0 RecB-family nuclease (DUF2122) DUF972 PF06156.8 EIW78259.1 - 0.092 13.0 6.0 0.19 12.1 3.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Nup88 PF10168.4 EIW78259.1 - 0.12 10.2 4.2 0.14 10.0 2.9 1.0 1 0 0 1 1 1 0 Nuclear pore component MRP-S27 PF10037.4 EIW78259.1 - 0.13 11.1 6.5 0.14 11.0 4.5 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 TBPIP PF07106.8 EIW78259.1 - 0.24 10.9 5.9 0.27 10.7 4.1 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.7 EIW78259.1 - 0.29 10.1 7.4 0.34 9.9 5.1 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF919 PF06034.6 EIW78259.1 - 0.29 10.7 3.0 3.3 7.3 0.5 2.6 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Reo_sigmaC PF04582.7 EIW78259.1 - 0.56 9.3 3.5 0.67 9.0 2.5 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein HALZ PF02183.13 EIW78259.1 - 0.61 9.8 10.3 0.32 10.7 2.9 2.8 1 1 2 3 3 3 0 Homeobox associated leucine zipper Spectrin PF00435.16 EIW78259.1 - 0.77 10.0 7.7 0.86 9.9 3.2 1.8 1 1 0 2 2 2 0 Spectrin repeat Mnd1 PF03962.10 EIW78259.1 - 1.1 8.8 5.8 1.3 8.6 4.0 1.1 1 0 0 1 1 1 0 Mnd1 family WXG100 PF06013.7 EIW78259.1 - 1.1 9.2 5.0 5.7 7.0 0.5 2.5 2 1 0 2 2 2 0 Proteins of 100 residues with WXG OmpH PF03938.9 EIW78259.1 - 1.7 8.5 7.5 2.3 8.1 5.2 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) UPF0184 PF03670.8 EIW78259.1 - 2.1 8.5 5.3 2.5 8.3 1.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) DUF4140 PF13600.1 EIW78259.1 - 2.3 8.6 8.0 3.7 8.0 4.9 1.8 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.6 EIW78259.1 - 5.1 6.8 8.3 7.5 6.2 3.0 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4164 PF13747.1 EIW78259.1 - 5.3 7.2 12.2 8 6.6 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) IncA PF04156.9 EIW78259.1 - 7 6.1 11.6 16 4.9 8.0 1.6 1 1 0 1 1 1 0 IncA protein HAUS-augmin3 PF14932.1 EIW78260.1 - 0.00038 19.7 6.6 0.00046 19.4 4.6 1.0 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 3 bZIP_1 PF00170.16 EIW78260.1 - 0.0046 16.8 3.0 0.0046 16.8 2.1 2.2 2 0 0 2 2 2 1 bZIP transcription factor Herpes_BLRF2 PF05812.7 EIW78260.1 - 0.0067 16.2 3.8 0.0067 16.2 2.7 1.7 1 1 0 1 1 1 1 Herpesvirus BLRF2 protein DUF1875 PF08961.5 EIW78260.1 - 0.021 14.1 1.4 0.021 14.1 1.0 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1875) HALZ PF02183.13 EIW78260.1 - 0.029 14.0 5.6 0.053 13.2 1.7 2.2 1 1 1 2 2 2 0 Homeobox associated leucine zipper TSC22 PF01166.13 EIW78260.1 - 0.054 13.4 3.3 0.11 12.4 2.3 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family DUF904 PF06005.7 EIW78260.1 - 0.13 12.5 9.6 0.048 13.9 2.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF904) APG6 PF04111.7 EIW78260.1 - 0.17 10.9 9.4 0.21 10.5 6.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EIW78260.1 - 0.2 11.5 11.4 0.31 10.8 7.9 1.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Dor1 PF04124.7 EIW78260.1 - 0.27 9.6 6.2 0.32 9.3 4.3 1.1 1 0 0 1 1 1 0 Dor1-like family DUF948 PF06103.6 EIW78260.1 - 0.43 10.4 3.7 0.61 9.9 2.6 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) PilJ PF13675.1 EIW78260.1 - 0.43 10.9 7.8 1.1 9.5 5.4 1.6 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term UPF0242 PF06785.6 EIW78260.1 - 0.61 8.7 7.8 0.71 8.4 5.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) GAS PF13851.1 EIW78260.1 - 0.81 8.8 11.8 1.3 8.1 8.2 1.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 EIW78260.1 - 0.83 10.0 8.3 0.21 11.9 3.0 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 EIW78260.1 - 1.2 8.7 11.1 1.6 8.3 7.7 1.1 1 0 0 1 1 1 0 Mnd1 family IncA PF04156.9 EIW78260.1 - 1.3 8.5 13.7 1.7 8.2 9.5 1.2 1 0 0 1 1 1 0 IncA protein DivIVA PF05103.8 EIW78260.1 - 1.4 8.9 11.2 0.11 12.5 3.8 1.8 1 1 1 2 2 2 0 DivIVA protein DUF342 PF03961.8 EIW78260.1 - 4.2 5.6 6.7 4.9 5.4 4.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Spc24 PF08286.6 EIW78260.1 - 8.1 6.1 9.7 1.3 8.7 3.5 1.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 WD40 PF00400.27 EIW78261.1 - 0.0046 16.7 7.9 1 9.3 0.0 5.4 5 0 0 5 5 5 1 WD domain, G-beta repeat PD40 PF07676.7 EIW78261.1 - 0.011 15.3 0.2 2 8.1 0.2 3.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Cys_Met_Meta_PP PF01053.15 EIW78262.1 - 9.6e-19 66.9 0.0 2.1e-18 65.7 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EIW78262.1 - 0.00051 19.0 0.0 0.00078 18.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II KAR9 PF08580.5 EIW78262.1 - 3.9 5.6 6.1 6.1 4.9 4.2 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Vps39_2 PF10367.4 EIW78263.1 - 3.7e-10 39.9 0.0 1.1e-09 38.4 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 EIW78263.1 - 1.1e-07 31.8 0.6 7.3e-07 29.1 0.0 2.7 2 1 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.15 EIW78263.1 - 5.8e-06 25.9 0.3 0.07 12.7 0.0 4.3 4 1 0 4 4 4 2 Region in Clathrin and VPS RabGAP-TBC PF00566.13 EIW78264.1 - 1.5e-21 76.8 0.0 2e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Lamp PF01299.12 EIW78264.1 - 2.8 6.9 10.4 9.6 5.2 0.2 2.3 2 0 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) RPAP1_N PF08621.5 EIW78264.1 - 7.1 6.3 6.1 0.49 10.0 0.1 2.2 3 0 0 3 3 3 0 RPAP1-like, N-terminal bZIP_1 PF00170.16 EIW78265.1 - 0.0015 18.4 9.9 0.0055 16.6 0.6 2.4 2 0 0 2 2 2 1 bZIP transcription factor DUF904 PF06005.7 EIW78265.1 - 0.0034 17.6 6.8 0.0034 17.6 4.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF904) MIS13 PF08202.6 EIW78265.1 - 0.026 13.6 4.1 0.03 13.3 2.8 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family APG6 PF04111.7 EIW78265.1 - 0.13 11.3 8.0 0.15 11.0 5.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 UPF0184 PF03670.8 EIW78265.1 - 0.14 12.3 2.6 0.29 11.3 1.8 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0184) DivIVA PF05103.8 EIW78265.1 - 0.17 11.9 7.4 0.095 12.7 3.2 1.8 2 0 0 2 2 2 0 DivIVA protein HAUS-augmin3 PF14932.1 EIW78265.1 - 0.46 9.6 11.5 0.54 9.3 8.0 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Lsr2 PF11774.3 EIW78265.1 - 0.82 9.6 4.5 0.27 11.1 0.5 2.0 1 1 1 2 2 2 0 Lsr2 Cluap1 PF10234.4 EIW78265.1 - 0.83 8.7 7.8 0.97 8.5 5.4 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 DUF972 PF06156.8 EIW78265.1 - 0.93 9.8 8.6 0.53 10.6 4.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ATG16 PF08614.6 EIW78265.1 - 1.5 8.6 15.7 2.4 7.9 10.9 1.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Med15 PF09606.5 EIW78265.1 - 3.1 5.8 24.6 3.8 5.6 17.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal KIAA1430 PF13879.1 EIW78265.1 - 3.7 8.0 16.1 16 5.9 0.2 2.7 2 1 0 2 2 2 0 KIAA1430 homologue DUF4407 PF14362.1 EIW78265.1 - 7.2 5.4 9.7 10 4.9 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.16 EIW78266.1 - 0.0006 19.7 0.9 0.0006 19.7 0.7 2.3 2 0 0 2 2 2 1 bZIP transcription factor DUF904 PF06005.7 EIW78266.1 - 0.00061 20.0 2.4 0.00061 20.0 1.6 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF904) UPF0184 PF03670.8 EIW78266.1 - 0.0066 16.5 0.7 0.0066 16.5 0.5 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0184) DUF2383 PF09537.5 EIW78266.1 - 0.021 15.0 2.1 0.063 13.5 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF2383) APG6 PF04111.7 EIW78266.1 - 0.054 12.5 2.9 0.063 12.3 2.0 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 HAUS-augmin3 PF14932.1 EIW78266.1 - 0.069 12.3 5.0 0.086 12.0 3.5 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF342 PF03961.8 EIW78266.1 - 0.078 11.3 1.4 0.086 11.2 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FlgN PF05130.7 EIW78266.1 - 0.085 13.1 5.9 0.11 12.7 4.1 1.1 1 0 0 1 1 1 0 FlgN protein Atg14 PF10186.4 EIW78266.1 - 0.096 11.6 4.4 0.13 11.1 3.1 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2968 PF11180.3 EIW78266.1 - 0.11 11.8 4.6 0.13 11.5 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) EMP24_GP25L PF01105.19 EIW78266.1 - 0.12 12.1 0.9 0.15 11.8 0.7 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD BH3 PF15285.1 EIW78266.1 - 0.12 11.9 0.1 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 Beclin-1 BH3 domain, Bcl-2-interacting DUF948 PF06103.6 EIW78266.1 - 0.17 11.7 0.6 0.24 11.3 0.4 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) CDC37_N PF03234.9 EIW78266.1 - 0.21 11.8 2.1 0.35 11.1 1.5 1.3 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding SYCE1 PF15233.1 EIW78266.1 - 0.23 11.3 3.7 0.14 12.0 1.5 1.4 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 V_ATPase_I PF01496.14 EIW78266.1 - 0.28 9.0 1.5 0.31 8.8 1.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HALZ PF02183.13 EIW78266.1 - 0.41 10.4 3.8 0.34 10.6 0.9 2.1 2 1 1 3 3 2 0 Homeobox associated leucine zipper DUF812 PF05667.6 EIW78266.1 - 0.72 8.2 6.9 0.86 8.0 4.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF972 PF06156.8 EIW78266.1 - 0.79 10.1 5.0 0.45 10.8 2.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Uds1 PF15456.1 EIW78266.1 - 1 9.3 6.1 1.3 8.9 4.3 1.2 1 0 0 1 1 1 0 Up-regulated During Septation CCDC155 PF14662.1 EIW78266.1 - 1.3 8.5 10.2 0.28 10.7 1.9 2.0 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DivIC PF04977.10 EIW78266.1 - 1.4 8.4 4.5 3.4 7.2 0.7 2.2 2 0 0 2 2 2 0 Septum formation initiator KIAA1430 PF13879.1 EIW78266.1 - 1.4 9.3 8.1 0.71 10.3 0.7 2.1 1 1 0 2 2 2 0 KIAA1430 homologue bZIP_Maf PF03131.12 EIW78266.1 - 1.4 9.2 10.2 1.1 9.6 3.5 2.0 1 1 1 2 2 2 0 bZIP Maf transcription factor DivIVA PF05103.8 EIW78266.1 - 1.8 8.5 5.7 0.38 10.8 0.8 1.9 1 1 1 2 2 2 0 DivIVA protein Nup54 PF13874.1 EIW78266.1 - 2.5 7.7 8.0 1.3 8.7 1.9 2.1 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF3552 PF12072.3 EIW78266.1 - 3.1 6.9 10.3 9.6 5.3 7.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) IncA PF04156.9 EIW78266.1 - 4.9 6.7 8.9 11 5.5 6.1 1.5 1 1 0 1 1 1 0 IncA protein HALZ PF02183.13 EIW78267.1 - 0.0045 16.6 2.9 0.0069 16.0 1.4 1.8 1 1 0 1 1 1 1 Homeobox associated leucine zipper DUF4201 PF13870.1 EIW78267.1 - 0.017 14.5 2.0 0.02 14.3 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF904 PF06005.7 EIW78267.1 - 0.018 15.3 3.5 0.023 14.9 2.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 EIW78267.1 - 0.022 15.1 0.9 0.026 14.8 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) APG6 PF04111.7 EIW78267.1 - 0.05 12.6 2.2 0.059 12.3 1.5 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Nup88 PF10168.4 EIW78267.1 - 0.051 11.4 0.4 0.055 11.3 0.3 1.0 1 0 0 1 1 1 0 Nuclear pore component IncA PF04156.9 EIW78267.1 - 0.055 13.0 1.5 0.062 12.8 1.1 1.1 1 0 0 1 1 1 0 IncA protein ZYG-11_interact PF05884.7 EIW78267.1 - 0.19 10.7 1.5 0.21 10.6 1.1 1.0 1 0 0 1 1 1 0 Interactor of ZYG-11 FliD_C PF07195.7 EIW78267.1 - 0.37 10.0 3.1 0.42 9.8 2.2 1.0 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus FlxA PF14282.1 EIW78267.1 - 7.9 6.4 10.6 15 5.6 7.4 1.5 1 1 0 1 1 1 0 FlxA-like protein WD40 PF00400.27 EIW78268.1 - 0.16 11.8 10.1 20 5.2 0.0 6.1 6 0 0 6 6 6 0 WD domain, G-beta repeat Ribosomal_L28 PF00830.14 EIW78272.1 - 0.059 13.2 0.0 4 7.3 0.0 2.2 2 0 0 2 2 2 0 Ribosomal L28 family AAA_16 PF13191.1 EIW78273.1 - 4.8e-06 26.6 0.0 4.8e-06 26.6 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EIW78273.1 - 1.2e-05 25.0 0.0 1.3e-05 24.9 0.0 1.0 1 0 0 1 1 1 1 NACHT domain APS_kinase PF01583.15 EIW78273.1 - 2.5e-05 24.0 0.0 2.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.1 EIW78273.1 - 0.00029 21.0 0.0 0.00029 21.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EIW78273.1 - 0.00066 19.8 0.0 0.0007 19.7 0.0 1.2 1 0 0 1 1 1 1 RNA helicase PRK PF00485.13 EIW78273.1 - 0.0013 18.2 0.0 0.0014 18.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family ResIII PF04851.10 EIW78273.1 - 0.0088 15.8 0.0 0.0088 15.8 0.0 1.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ABC_tran PF00005.22 EIW78273.1 - 0.015 15.6 0.0 0.015 15.6 0.0 1.1 1 0 0 1 1 1 0 ABC transporter Arch_ATPase PF01637.13 EIW78273.1 - 0.015 15.0 0.0 0.015 15.0 0.0 1.0 1 0 0 1 1 1 0 Archaeal ATPase Zeta_toxin PF06414.7 EIW78273.1 - 0.021 13.9 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.1 EIW78273.1 - 0.021 14.3 0.2 0.029 13.8 0.1 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.1 EIW78273.1 - 0.032 14.2 0.0 0.037 14.0 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.1 EIW78273.1 - 0.053 13.8 0.0 0.053 13.8 0.0 1.1 1 0 0 1 1 1 0 AAA domain Torsin PF06309.6 EIW78273.1 - 0.061 13.2 0.0 0.069 13.0 0.0 1.2 1 0 0 1 1 1 0 Torsin AAA_5 PF07728.9 EIW78273.1 - 0.087 12.5 0.0 0.096 12.4 0.0 1.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Abhydrolase_1 PF00561.15 EIW78274.1 - 7.9e-08 32.1 0.0 8.6e-08 32.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIW78274.1 - 6e-07 29.5 0.0 6.5e-07 29.4 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family LppC PF04348.8 EIW78276.1 - 0.058 11.9 0.0 0.085 11.4 0.0 1.1 1 0 0 1 1 1 0 LppC putative lipoprotein Cep57_MT_bd PF06657.8 EIW78277.1 - 0.013 15.4 0.1 0.026 14.4 0.0 1.5 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 OHCU_decarbox PF09349.5 EIW78278.1 - 0.02 15.1 0.0 12 6.1 0.0 2.7 2 0 0 2 2 2 0 OHCU decarboxylase Abhydrolase_6 PF12697.2 EIW78279.1 - 1.1e-16 61.3 0.1 1.3e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW78279.1 - 2.6e-14 53.3 0.0 3.3e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW78279.1 - 0.00012 21.8 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BpuSI_N PF15516.1 EIW78279.1 - 0.021 14.5 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 BpuSI N-terminal domain Thioesterase PF00975.15 EIW78279.1 - 0.05 13.8 0.3 0.066 13.4 0.2 1.3 1 1 0 1 1 1 0 Thioesterase domain Esterase PF00756.15 EIW78279.1 - 0.058 12.8 0.0 0.066 12.6 0.0 1.1 1 0 0 1 1 1 0 Putative esterase Lipase_3 PF01764.20 EIW78279.1 - 0.065 12.8 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_8 PF06259.7 EIW78279.1 - 0.14 11.6 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase DUF915 PF06028.6 EIW78279.1 - 0.15 11.1 0.1 3.2 6.7 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) SKN1 PF03935.10 EIW78281.1 - 1.3e-189 630.5 5.9 1.5e-189 630.3 4.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) zf-MYND PF01753.13 EIW78282.1 - 2.1e-10 40.3 21.2 3.8e-10 39.4 14.7 1.4 1 0 0 1 1 1 1 MYND finger Ank_2 PF12796.2 EIW78282.1 - 1.2e-09 38.3 0.0 1e-07 32.1 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EIW78282.1 - 1.1e-07 31.3 0.6 0.0076 16.0 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EIW78282.1 - 5.9e-05 22.9 0.3 0.32 11.3 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 EIW78282.1 - 0.00024 21.2 0.0 0.00072 19.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIW78282.1 - 0.0022 18.4 0.2 0.058 13.9 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) zf-HIT PF04438.11 EIW78282.1 - 2.2 7.9 8.2 4.4 7.0 5.7 1.5 1 0 0 1 1 1 0 HIT zinc finger Ank_2 PF12796.2 EIW78283.1 - 7.8e-14 51.7 0.0 3.3e-07 30.5 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) zf-MYND PF01753.13 EIW78283.1 - 6.8e-12 45.0 17.6 1.1e-11 44.3 12.2 1.3 1 0 0 1 1 1 1 MYND finger Ank_4 PF13637.1 EIW78283.1 - 7.8e-10 38.9 0.0 0.00037 20.9 0.0 3.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 EIW78283.1 - 5e-09 35.5 1.0 0.3 10.9 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 EIW78283.1 - 1.4e-08 34.1 0.1 4.2 7.9 0.0 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EIW78283.1 - 4.5e-07 29.8 0.9 0.019 15.1 0.1 4.4 3 1 2 5 5 5 3 Ankyrin repeats (many copies) FYVE_2 PF02318.11 EIW78283.1 - 0.13 12.1 6.2 0.23 11.3 4.3 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger zf-ribbon_3 PF13248.1 EIW78283.1 - 1.2 8.3 3.6 3.4 6.9 1.0 2.6 2 1 1 3 3 3 0 zinc-ribbon domain MAM33 PF02330.11 EIW78284.1 - 1.1e-35 123.2 0.0 1.8e-35 122.5 0.0 1.3 1 1 0 1 1 1 1 Mitochondrial glycoprotein zf-MYND PF01753.13 EIW78285.1 - 8e-11 41.6 14.5 2e-10 40.3 10.0 1.7 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 EIW78286.1 - 2e-09 37.1 15.1 3.4e-09 36.4 10.5 1.4 1 0 0 1 1 1 1 MYND finger TPR_11 PF13414.1 EIW78286.1 - 0.092 12.4 0.0 3 7.5 0.0 2.9 3 0 0 3 3 3 0 TPR repeat zf-Mss51 PF13824.1 EIW78286.1 - 0.42 10.5 8.7 1.2 9.0 6.0 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Zn_clus PF00172.13 EIW78287.1 - 0.0015 18.3 12.0 0.0024 17.7 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_N_3 PF13417.1 EIW78289.1 - 6.2e-07 29.5 0.0 1.1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW78289.1 - 7.8e-07 29.1 0.0 1.5e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW78289.1 - 4e-06 26.7 0.0 1.3e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW78289.1 - 1.5e-05 24.8 0.0 2.6e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW78289.1 - 0.00012 21.9 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Metallophos PF00149.23 EIW78289.1 - 0.034 13.5 0.0 0.034 13.5 0.0 1.1 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase DDE_Tnp_ISAZ013 PF07592.6 EIW78289.1 - 0.057 12.1 0.0 0.075 11.7 0.0 1.1 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain GST_C_3 PF14497.1 EIW78289.1 - 0.077 13.4 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Oxidored_FMN PF00724.15 EIW78290.1 - 2.4e-70 237.2 0.0 3.2e-70 236.8 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DeoC PF01791.4 EIW78290.1 - 0.035 13.3 0.1 1.2 8.3 0.0 2.2 2 0 0 2 2 2 0 DeoC/LacD family aldolase Dus PF01207.12 EIW78290.1 - 0.14 10.9 0.2 4.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Herpes_capsid PF06112.6 EIW78291.1 - 1 9.3 11.5 0.91 9.5 1.7 2.6 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein CNH PF00780.17 EIW78292.1 - 5.7e-11 42.3 0.0 9.4e-11 41.6 0.0 1.4 1 1 0 1 1 1 1 CNH domain PMT_2 PF13231.1 EIW78293.1 - 1.5 8.7 13.3 1 9.2 8.1 1.6 1 1 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF1875 PF08961.5 EIW78294.1 - 8.6e-05 21.9 0.2 0.0001 21.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1875) HopW1-1 PF15457.1 EIW78294.1 - 0.02 13.9 0.4 0.024 13.6 0.3 1.2 1 0 0 1 1 1 0 Type III T3SS secreted effector HopW1-1/HopPmaA DUF4570 PF15134.1 EIW78294.1 - 0.029 14.1 1.8 0.042 13.6 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) DUF4470 PF14737.1 EIW78294.1 - 0.038 13.7 0.0 0.046 13.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4470) DUF2536 PF10750.4 EIW78294.1 - 0.045 13.3 1.4 0.071 12.7 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) bZIP_1 PF00170.16 EIW78294.1 - 0.3 11.0 4.3 0.3 11.0 2.2 1.7 1 1 0 1 1 1 0 bZIP transcription factor bZIP_2 PF07716.10 EIW78294.1 - 2.3 8.1 6.4 2.3 8.0 2.6 2.3 2 1 1 3 3 3 0 Basic region leucine zipper H-kinase_dim PF02895.9 EIW78295.1 - 0.015 15.6 0.8 0.015 15.6 0.6 1.6 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain HAUS-augmin3 PF14932.1 EIW78295.1 - 0.036 13.2 0.5 0.041 13.0 0.3 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF904 PF06005.7 EIW78295.1 - 0.044 14.0 1.0 0.087 13.1 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) AAA_13 PF13166.1 EIW78295.1 - 0.051 12.0 0.4 0.062 11.7 0.3 1.0 1 0 0 1 1 1 0 AAA domain APG6 PF04111.7 EIW78295.1 - 0.11 11.5 0.7 0.14 11.2 0.5 1.0 1 0 0 1 1 1 0 Autophagy protein Apg6 Serglycin PF04360.7 EIW78295.1 - 0.14 11.8 7.4 0.11 12.1 4.1 1.6 1 1 1 2 2 2 0 Serglycin Syntaxin PF00804.20 EIW78295.1 - 0.17 12.0 1.7 0.51 10.5 1.2 1.7 1 1 1 2 2 2 0 Syntaxin bZIP_1 PF00170.16 EIW78295.1 - 7.8 6.5 9.1 0.3 11.0 0.8 2.1 2 0 0 2 2 2 0 bZIP transcription factor SKN1 PF03935.10 EIW78296.1 - 3.6e-180 599.4 7.1 4.2e-180 599.2 4.9 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) zf-MYND PF01753.13 EIW78297.1 - 9.1e-13 47.8 14.2 1.4e-12 47.2 9.8 1.3 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 EIW78297.1 - 0.0041 16.7 6.9 0.0072 15.9 4.8 1.4 1 0 0 1 1 1 1 HIT zinc finger zf-Mss51 PF13824.1 EIW78297.1 - 0.12 12.2 7.9 0.26 11.1 5.5 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 PolC_DP2 PF03833.8 EIW78297.1 - 0.42 8.2 3.7 0.49 8.0 2.6 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zinc_ribbon_2 PF13240.1 EIW78297.1 - 0.79 9.2 6.8 3.3 7.3 0.6 2.6 1 1 1 2 2 2 0 zinc-ribbon domain Aldedh PF00171.17 EIW78299.1 - 7.2e-85 285.0 0.0 8.7e-85 284.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4158 PF13700.1 EIW78299.1 - 0.016 14.7 0.1 0.025 14.0 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) F-box PF00646.28 EIW78300.1 - 0.04 13.5 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 EIW78300.1 - 0.051 13.3 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 F-box-like DUF791 PF05631.9 EIW78301.1 - 1.1e-66 224.9 3.9 2e-66 224.1 2.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 EIW78301.1 - 2.8e-12 46.0 30.0 2.8e-12 46.0 20.8 2.7 1 1 2 3 3 3 2 Major Facilitator Superfamily RRM_1 PF00076.17 EIW78302.1 - 1.3e-42 143.2 0.0 6.5e-16 57.7 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW78302.1 - 9.1e-28 96.0 0.0 8e-11 41.7 0.0 3.1 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW78302.1 - 4.7e-21 74.3 0.0 6.7e-06 25.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EIW78302.1 - 0.00018 21.2 0.0 0.0068 16.1 0.0 3.0 3 2 0 3 3 3 1 Limkain b1 RRM_3 PF08777.6 EIW78302.1 - 0.0071 16.1 0.0 6 6.7 0.0 3.1 3 0 0 3 3 3 1 RNA binding motif DUF3343 PF11823.3 EIW78302.1 - 0.025 13.8 0.0 0.086 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3343) HET PF06985.6 EIW78303.1 - 9.4e-12 45.2 0.6 4e-11 43.2 0.2 2.2 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 EIW78304.1 - 1.5e-12 47.8 0.0 3.9e-12 46.4 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 EIW78305.1 - 5.9e-16 58.8 1.2 1e-15 58.1 0.8 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ADH_N PF08240.7 EIW78306.1 - 1.4e-10 40.9 0.0 2.3e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW78306.1 - 6.5e-10 38.6 0.0 1.1e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EIW78306.1 - 0.19 11.2 0.0 0.19 11.2 0.0 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Glyco_transf_20 PF00982.16 EIW78307.1 - 1.9e-144 481.7 0.0 3.9e-77 259.7 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EIW78307.1 - 7.7e-74 247.5 0.0 1.9e-73 246.2 0.0 1.6 2 0 0 2 2 2 1 Trehalose-phosphatase HAD PF12710.2 EIW78307.1 - 0.1 12.7 0.1 19 5.3 0.0 2.9 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Mem_trans PF03547.13 EIW78308.1 - 5.1e-41 140.2 7.5 2e-36 125.0 1.2 2.4 2 0 0 2 2 2 2 Membrane transport protein DUF2207 PF09972.4 EIW78308.1 - 0.26 9.8 0.2 6.6 5.2 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Amino_oxidase PF01593.19 EIW78309.1 - 3.4e-26 92.3 0.1 9.8e-17 61.1 0.1 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EIW78309.1 - 2.5e-06 27.4 0.0 5.5e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIW78309.1 - 0.00049 20.2 0.0 0.002 18.2 0.0 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HET PF06985.6 EIW78310.1 - 5.1e-13 49.3 0.3 6e-13 49.1 0.2 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Phasin PF05597.6 EIW78311.1 - 0.0026 17.5 3.5 0.004 16.9 2.4 1.4 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Topoisom_I_N PF02919.10 EIW78311.1 - 0.11 11.7 6.6 0.15 11.2 4.6 1.2 1 0 0 1 1 1 0 Eukaryotic DNA topoisomerase I, DNA binding fragment PCMT PF01135.14 EIW78312.1 - 2.3e-65 220.0 0.0 2.7e-65 219.8 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EIW78312.1 - 1.6e-08 34.3 0.0 2.7e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW78312.1 - 1.1e-07 31.6 0.0 1.7e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW78312.1 - 1.4e-07 32.0 0.0 2.4e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EIW78312.1 - 4.6e-07 29.6 0.0 6.3e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW78312.1 - 4.4e-06 26.7 0.0 9.4e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW78312.1 - 0.00022 21.6 0.0 0.00051 20.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EIW78312.1 - 0.00027 20.1 0.0 0.00038 19.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 EIW78312.1 - 0.0013 18.1 0.2 0.0091 15.3 0.0 2.0 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW MTS PF05175.9 EIW78312.1 - 0.0015 17.9 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EIW78312.1 - 0.013 14.6 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EIW78312.1 - 0.018 15.0 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase GCD14 PF08704.5 EIW78312.1 - 0.019 14.4 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_25 PF13649.1 EIW78312.1 - 0.036 14.4 0.0 0.089 13.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EIW78312.1 - 0.13 11.3 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Mem_trans PF03547.13 EIW78313.1 - 6.7e-44 149.7 5.2 1.1e-37 129.2 0.1 2.3 2 0 0 2 2 2 2 Membrane transport protein MscS_TM PF12794.2 EIW78313.1 - 6.1 5.3 15.0 0.22 10.0 2.8 2.8 2 1 1 3 3 3 0 Mechanosensitive ion channel inner membrane domain 1 APS_kinase PF01583.15 EIW78315.1 - 0.045 13.4 0.0 0.053 13.1 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_16 PF13191.1 EIW78315.1 - 0.047 13.6 0.0 0.047 13.6 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 EIW78315.1 - 0.049 13.8 0.0 0.063 13.4 0.0 1.3 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 EIW78315.1 - 0.13 11.8 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 NACHT domain Pkinase_Tyr PF07714.12 EIW78316.1 - 1e-38 132.9 0.0 1.8e-38 132.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EIW78316.1 - 5e-38 130.7 0.0 7.8e-38 130.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EIW78316.1 - 0.028 14.1 0.0 0.075 12.7 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW78316.1 - 0.12 11.3 0.0 0.3 10.0 0.0 1.6 1 1 0 1 1 1 0 Kinase-like DUF155 PF02582.9 EIW78317.1 - 1.5e-42 145.4 0.0 2.3e-42 144.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 HECT_2 PF09814.4 EIW78318.1 - 3.8e-29 101.5 0.0 7.8e-29 100.4 0.0 1.4 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding GRAB PF10375.4 EIW78319.1 - 2.9e-06 26.6 0.6 5.6e-06 25.7 0.4 1.5 1 0 0 1 1 1 1 GRIP-related Arf-binding domain GRIP PF01465.15 EIW78319.1 - 8.7e-05 21.9 0.0 0.00019 20.8 0.0 1.5 1 0 0 1 1 1 1 GRIP domain LPP PF04728.8 EIW78319.1 - 0.058 13.2 5.1 0.11 12.3 0.2 3.2 2 2 1 3 3 3 0 Lipoprotein leucine-zipper Rb_C PF08934.5 EIW78319.1 - 2.1 7.9 5.8 0.37 10.3 0.7 2.2 2 0 0 2 2 2 0 Rb C-terminal domain DUF3496 PF12001.3 EIW78319.1 - 2.5 8.3 10.9 8.6 6.6 0.4 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3496) FliD_N PF02465.13 EIW78319.1 - 3.2 8.1 8.6 1 9.7 2.1 2.7 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus F-box PF00646.28 EIW78320.1 - 5e-08 32.3 2.4 1.4e-07 30.9 1.7 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW78320.1 - 4e-07 29.6 2.0 1e-06 28.3 1.4 1.7 1 0 0 1 1 1 1 F-box-like Histone PF00125.19 EIW78321.1 - 1.2e-24 86.1 0.7 1.5e-24 85.8 0.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIW78321.1 - 2.4e-09 37.1 0.0 3.3e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EIW78322.1 - 1.1e-21 76.6 0.2 1.7e-21 76.1 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIW78322.1 - 1.5e-05 24.9 0.1 3.6e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EIW78322.1 - 0.0004 20.6 0.0 0.00073 19.7 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF1018 PF06252.7 EIW78322.1 - 0.032 14.7 0.4 0.043 14.3 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.8 EIW78322.1 - 0.067 12.6 0.0 0.089 12.2 0.0 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain Delta_lysin PF05372.6 EIW78323.1 - 0.048 13.0 1.6 2.6 7.5 0.0 2.3 2 0 0 2 2 2 0 Delta lysin family Mito_fiss_reg PF05308.6 EIW78323.1 - 0.099 11.9 0.2 0.14 11.5 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator PNRC PF15365.1 EIW78324.1 - 0.026 14.5 1.9 0.026 14.5 1.3 4.1 3 1 0 3 3 3 0 Proline-rich nuclear receptor coactivator Homoserine_dh PF00742.14 EIW78325.1 - 4.6e-49 166.5 0.0 6.4e-49 166.0 0.0 1.2 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EIW78325.1 - 3.4e-14 53.2 0.0 1e-13 51.6 0.0 1.8 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EIW78325.1 - 0.1 12.9 0.0 0.25 11.6 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain RNA_pol_3_Rpc31 PF11705.3 EIW78326.1 - 1.6e-28 100.2 30.2 1.2e-27 97.4 20.9 2.1 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 Shadoo PF14999.1 EIW78326.1 - 7.1 6.5 13.1 16 5.3 9.1 1.6 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective RRM_1 PF00076.17 EIW78327.1 - 1.7e-13 49.9 0.0 2.3e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW78327.1 - 3.9e-09 36.3 0.0 5.5e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF3235 PF11574.3 EIW78327.1 - 0.026 14.7 0.9 0.034 14.3 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) RRM_5 PF13893.1 EIW78327.1 - 0.091 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HET PF06985.6 EIW78328.1 - 1.2e-15 57.8 2.9 2e-15 57.1 2.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) PPTA PF01239.17 EIW78329.1 - 3.6e-41 136.8 12.0 3.9e-09 35.4 0.0 5.3 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat PSCyt2 PF07583.6 EIW78329.1 - 0.017 14.6 0.2 0.029 13.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) Pkinase_Tyr PF07714.12 EIW78331.1 - 3.6e-10 39.3 0.0 5.1e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EIW78331.1 - 8.1e-08 31.7 0.0 1.1e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF4209 PF13910.1 EIW78331.1 - 0.0034 17.4 0.0 0.0066 16.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4209) AAA_16 PF13191.1 EIW78332.1 - 0.00016 21.7 0.2 0.00032 20.7 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EIW78332.1 - 0.00099 18.8 0.0 0.0012 18.6 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EIW78332.1 - 0.0022 17.7 0.0 0.003 17.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain APS_kinase PF01583.15 EIW78332.1 - 0.004 16.8 0.0 0.0093 15.6 0.0 1.6 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_22 PF13401.1 EIW78332.1 - 0.0056 16.8 0.0 0.016 15.3 0.0 1.7 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.1 EIW78332.1 - 0.019 14.4 0.1 0.034 13.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 EIW78332.1 - 0.021 13.7 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 EIW78332.1 - 0.034 14.3 0.0 0.052 13.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 EIW78332.1 - 0.15 12.3 0.1 0.21 11.8 0.0 1.4 1 1 0 1 1 1 0 ABC transporter APH PF01636.18 EIW78333.1 - 7.2e-07 29.1 0.1 7.8e-06 25.7 0.1 2.0 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EIW78333.1 - 3.1e-05 23.4 0.0 6.6e-05 22.3 0.0 1.4 2 0 0 2 2 2 1 RIO1 family Pkinase PF00069.20 EIW78333.1 - 6.2e-05 22.2 0.0 7.7e-05 21.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain YrbL-PhoP_reg PF10707.4 EIW78333.1 - 0.054 12.8 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 EIW78334.1 - 7.7e-07 29.0 2.0 2.3e-05 24.2 0.0 2.9 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.20 EIW78334.1 - 0.00027 20.1 0.0 0.00049 19.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EIW78334.1 - 0.0025 17.1 0.0 0.0064 15.8 0.0 1.6 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 EIW78334.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 EIW78335.1 - 1.6e-10 41.1 14.2 8.3e-06 25.7 0.0 4.7 5 2 1 7 7 7 2 Phosphotransferase enzyme family RIO1 PF01163.17 EIW78335.1 - 1.2e-08 34.4 1.3 0.0012 18.2 0.0 3.2 3 0 0 3 3 3 2 RIO1 family Pkinase PF00069.20 EIW78335.1 - 7.5e-07 28.5 0.0 0.0035 16.5 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain RNase_H2-Ydr279 PF09468.5 EIW78335.1 - 0.0037 16.5 1.7 0.006 15.8 1.2 1.2 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) YrbL-PhoP_reg PF10707.4 EIW78335.1 - 0.0054 16.0 0.0 1.2 8.4 0.0 3.0 3 0 0 3 3 3 1 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 EIW78335.1 - 0.08 12.4 3.0 5.1 6.6 0.0 2.7 3 0 0 3 3 3 0 Choline/ethanolamine kinase TP53IP5 PF15331.1 EIW78335.1 - 0.21 11.4 8.4 0.41 10.5 5.8 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 FAM60A PF15396.1 EIW78335.1 - 0.25 11.0 8.0 0.63 9.7 5.5 1.6 1 0 0 1 1 1 0 Protein Family FAM60A PBP1_TM PF14812.1 EIW78335.1 - 2.9 8.2 11.4 13 6.1 7.9 2.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal LSM PF01423.17 EIW78336.1 - 8e-16 57.3 0.1 9.7e-16 57.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain Flag1_repress PF03614.8 EIW78336.1 - 0.017 14.7 0.0 0.029 13.9 0.0 1.5 1 1 0 1 1 1 0 Repressor of phase-1 flagellin SM-ATX PF14438.1 EIW78336.1 - 0.094 12.6 0.1 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain TPT PF03151.11 EIW78337.1 - 8.9e-19 67.6 5.6 8.9e-19 67.6 3.9 2.5 3 0 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EIW78337.1 - 0.12 11.2 8.4 0.0086 15.0 2.1 1.7 2 0 0 2 2 2 0 UAA transporter family EamA PF00892.15 EIW78337.1 - 5 7.1 20.9 0.097 12.7 4.7 2.7 2 2 0 2 2 2 0 EamA-like transporter family F-box-like PF12937.2 EIW78338.1 - 8.5e-07 28.6 1.7 8.5e-07 28.6 1.2 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EIW78338.1 - 0.055 13.0 0.1 12 5.5 0.0 3.2 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) 6PF2K PF01591.13 EIW78339.1 - 3.8e-61 206.0 0.0 6.2e-61 205.3 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EIW78339.1 - 5.6e-21 75.2 0.0 1.8e-20 73.6 0.0 1.9 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EIW78339.1 - 0.00013 21.8 0.0 0.00027 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EIW78339.1 - 0.0051 16.0 0.0 0.01 15.1 0.0 1.5 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 EIW78339.1 - 0.0059 17.4 0.1 0.029 15.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIW78339.1 - 0.023 13.7 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin APS_kinase PF01583.15 EIW78339.1 - 0.14 11.7 0.1 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF4405 PF14358.1 EIW78340.1 - 0.074 13.2 4.8 1.2 9.3 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) RAI1 PF08652.6 EIW78341.1 - 4e-21 74.5 0.0 8e-21 73.5 0.0 1.5 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Polysacc_deac_1 PF01522.16 EIW78342.1 - 6.1e-28 96.9 0.0 1.2e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Syntaxin-6_N PF09177.6 EIW78343.1 - 0.069 13.5 0.0 0.52 10.7 0.0 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal APH PF01636.18 EIW78344.1 - 6.4e-05 22.7 0.3 0.0002 21.1 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIW78344.1 - 0.0006 19.2 0.1 0.00088 18.6 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.20 EIW78344.1 - 0.0087 15.2 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DUF3592 PF12158.3 EIW78344.1 - 0.071 12.8 0.2 0.09 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) APH PF01636.18 EIW78346.1 - 2.6e-07 30.6 1.5 3.6e-05 23.6 0.0 3.3 2 1 1 3 3 3 2 Phosphotransferase enzyme family Pkinase PF00069.20 EIW78346.1 - 0.00023 20.4 0.0 0.00041 19.5 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EIW78346.1 - 0.0042 16.4 0.0 0.0097 15.2 0.0 1.5 1 0 0 1 1 1 1 RIO1 family DuoxA PF10204.4 EIW78347.1 - 0.048 12.7 0.0 0.094 11.7 0.0 1.4 1 0 0 1 1 1 0 Dual oxidase maturation factor F-box-like PF12937.2 EIW78349.1 - 0.0017 17.9 0.4 0.0043 16.7 0.3 1.7 1 0 0 1 1 1 1 F-box-like DUF1344 PF07076.6 EIW78350.1 - 0.14 11.7 0.0 0.62 9.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1344) HLH PF00010.21 EIW78352.1 - 2.4e-09 36.7 0.0 7.7e-09 35.1 0.0 1.9 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RRM_1 PF00076.17 EIW78353.1 - 4.2e-13 48.7 0.0 7.1e-13 47.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW78353.1 - 2.2e-09 37.1 0.0 3.3e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW78353.1 - 3.3e-05 23.6 0.0 5.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EIW78353.1 - 0.00063 20.1 0.2 0.0012 19.2 0.1 1.4 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Arch_ATPase PF01637.13 EIW78356.1 - 0.0036 17.0 0.0 0.035 13.7 0.0 2.0 1 1 1 2 2 2 1 Archaeal ATPase NACHT PF05729.7 EIW78356.1 - 0.011 15.4 0.4 0.54 9.8 0.3 2.6 1 1 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 EIW78356.1 - 0.016 15.2 0.1 0.039 13.9 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain WD40 PF00400.27 EIW78356.1 - 0.018 14.8 0.3 0.094 12.6 0.0 2.4 2 0 0 2 2 2 0 WD domain, G-beta repeat ADH_zinc_N PF00107.21 EIW78357.1 - 2.1e-31 108.1 0.6 3.2e-31 107.5 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW78357.1 - 5.1e-28 96.9 0.4 8.4e-28 96.3 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIW78357.1 - 5.3e-05 24.1 0.9 8.7e-05 23.4 0.6 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EIW78357.1 - 0.092 12.3 0.2 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain p450 PF00067.17 EIW78358.1 - 9.9e-74 248.5 0.1 1.3e-73 248.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 VPS11_C PF12451.3 EIW78358.1 - 0.2 11.5 0.5 0.38 10.6 0.4 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 11 C terminal NACHT PF05729.7 EIW78360.1 - 4.2e-09 36.2 0.1 4.4e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EIW78360.1 - 0.0001 22.3 0.1 0.00035 20.6 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EIW78360.1 - 0.0017 18.1 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase APS_kinase PF01583.15 EIW78360.1 - 0.018 14.7 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.1 EIW78360.1 - 0.019 15.1 0.0 0.062 13.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EIW78360.1 - 0.085 13.0 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase PPR_3 PF13812.1 EIW78361.1 - 4.9e-06 26.4 14.4 0.00034 20.6 0.1 5.5 5 1 0 5 5 5 2 Pentatricopeptide repeat domain SWIRM PF04433.12 EIW78362.1 - 1.1e-34 118.4 0.0 1.8e-34 117.7 0.0 1.4 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EIW78362.1 - 1.5e-09 37.7 0.1 2.7e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EIW78362.1 - 1.8e-09 36.9 1.3 2.9e-09 36.3 0.9 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-bind_6 PF13921.1 EIW78362.1 - 3.6e-08 33.3 0.0 6.1e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Gpi16 PF04113.9 EIW78363.1 - 2e-113 379.3 0.0 6.7e-112 374.3 0.0 2.4 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Syntaxin-6_N PF09177.6 EIW78364.1 - 1.2e-13 51.2 0.2 1.5e-13 50.9 0.1 1.1 1 0 0 1 1 1 1 Syntaxin 6, N-terminal DUF1388 PF07142.7 EIW78365.1 - 4.6e-40 134.9 0.0 0.019 14.6 0.0 13.5 1 1 13 15 15 15 15 Repeat of unknown function (DUF1388) Extensin-like_C PF06904.7 EIW78365.1 - 0.049 13.4 3.0 1e+02 2.5 0.0 5.0 1 1 5 6 6 6 0 Extensin-like protein C-terminus COX4_pro_2 PF07835.7 EIW78366.1 - 1.2 9.1 4.6 2.5 8.1 3.2 1.5 1 0 0 1 1 1 0 Bacterial aa3 type cytochrome c oxidase subunit IV Pkinase PF00069.20 EIW78367.1 - 3.3e-67 226.3 0.0 3.8e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW78367.1 - 4e-33 114.5 0.0 9.4e-33 113.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW78367.1 - 4.1e-05 23.4 0.0 0.002 17.9 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EIW78367.1 - 0.13 11.0 0.1 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-C3HC4_3 PF13920.1 EIW78369.1 - 4e-11 42.4 4.9 1.5e-09 37.3 0.8 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW78369.1 - 1e-05 25.4 2.9 1e-05 25.4 2.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW78369.1 - 0.0043 16.7 2.9 0.033 13.9 0.6 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EIW78369.1 - 0.0059 16.4 1.1 0.0059 16.4 0.7 2.6 3 0 0 3 3 3 1 Ring finger domain Ribosomal_L18e PF00828.14 EIW78370.1 - 5.4e-36 123.8 0.2 7e-36 123.4 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 RNA_pol_L_2 PF13656.1 EIW78371.1 - 3.7e-26 90.3 0.0 5e-26 89.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EIW78371.1 - 1.5e-14 52.8 0.0 2.1e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain MMR_HSR1 PF01926.18 EIW78372.1 - 9.5e-11 41.6 0.0 2.2e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIW78372.1 - 6.4e-05 22.1 0.1 0.00014 21.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EIW78372.1 - 0.00065 19.7 0.1 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.13 EIW78372.1 - 0.0015 17.8 0.0 0.012 14.8 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Septin PF00735.13 EIW78372.1 - 0.0068 15.4 0.0 0.0096 14.9 0.0 1.2 1 0 0 1 1 1 1 Septin MCM PF00493.18 EIW78372.1 - 0.02 13.6 0.1 0.041 12.6 0.1 1.4 1 0 0 1 1 1 0 MCM2/3/5 family Arf PF00025.16 EIW78372.1 - 0.021 14.0 0.0 0.049 12.8 0.0 1.5 2 0 0 2 2 2 0 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIW78372.1 - 0.045 13.1 0.0 0.48 9.8 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_18 PF13238.1 EIW78372.1 - 0.059 13.6 0.0 0.15 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EIW78372.1 - 0.069 12.6 0.1 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 EIW78372.1 - 0.079 12.7 0.6 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Dynamin family MobB PF03205.9 EIW78372.1 - 0.11 12.1 0.0 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CMV_1a PF12467.3 EIW78373.1 - 0.11 12.8 1.7 0.21 11.9 1.2 1.5 1 0 0 1 1 1 0 Cucumber mosaic virus 1a protein family DUF605 PF04652.11 EIW78373.1 - 0.46 9.8 18.3 0.54 9.5 12.7 1.1 1 0 0 1 1 1 0 Vta1 like MCPVI PF02993.9 EIW78373.1 - 1.9 8.5 17.5 3.9 7.5 12.1 1.4 1 1 0 1 1 1 0 Minor capsid protein VI PAT1 PF09770.4 EIW78373.1 - 6.9 4.7 9.1 9.5 4.3 6.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF221 PF02714.10 EIW78374.1 - 1e-105 353.1 16.8 1.9e-105 352.3 11.7 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EIW78374.1 - 2.1e-36 124.8 2.3 2.1e-36 124.8 1.6 2.0 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EIW78374.1 - 1.5e-13 51.0 0.1 2.6e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF3779 PF12621.3 EIW78374.1 - 9.9e-13 47.7 0.0 2.4e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein Anoctamin PF04547.7 EIW78374.1 - 0.0052 15.4 0.1 0.017 13.8 0.1 1.8 1 0 0 1 1 1 1 Calcium-activated chloride channel EF-hand_5 PF13202.1 EIW78374.1 - 0.29 10.5 1.8 0.54 9.6 1.2 1.5 1 0 0 1 1 1 0 EF hand zf-C3HC4_3 PF13920.1 EIW78375.1 - 3.7e-13 48.9 22.8 4.4e-13 48.6 5.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EIW78375.1 - 9.4e-09 35.0 6.1 9.4e-09 35.0 4.2 2.9 2 1 0 2 2 2 1 FYVE zinc finger zf-C3HC4_2 PF13923.1 EIW78375.1 - 1.3e-07 31.5 8.5 1.3e-07 31.5 5.9 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW78375.1 - 4e-06 26.5 7.0 4e-06 26.5 4.9 2.7 2 1 0 2 2 2 1 Ring finger domain FYVE_2 PF02318.11 EIW78375.1 - 7.7e-06 25.8 4.9 7.7e-06 25.8 3.4 3.4 3 0 0 3 3 2 1 FYVE-type zinc finger zf-C3HC4 PF00097.20 EIW78375.1 - 3.3e-05 23.4 8.4 3.3e-05 23.4 5.8 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-P11 PF03854.9 EIW78375.1 - 0.0029 17.0 5.5 0.0029 17.0 3.8 3.1 3 1 0 3 3 3 1 P-11 zinc finger zf-RING_5 PF14634.1 EIW78375.1 - 0.0098 15.6 7.1 0.0098 15.6 4.9 2.6 2 0 0 2 2 2 1 zinc-RING finger domain DUF605 PF04652.11 EIW78375.1 - 0.14 11.5 23.7 0.0038 16.6 9.1 2.2 2 0 0 2 2 2 0 Vta1 like zf-UDP PF14569.1 EIW78375.1 - 0.28 10.9 8.7 0.85 9.4 0.9 3.1 2 0 0 2 2 2 0 Zinc-binding RING-finger UPF0547 PF10571.4 EIW78375.1 - 0.69 9.6 17.5 0.14 11.8 1.0 3.3 3 1 0 3 3 2 0 Uncharacterised protein family UPF0547 TFIIA PF03153.8 EIW78375.1 - 1.4 8.7 11.4 2 8.2 7.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C3HC4_4 PF15227.1 EIW78375.1 - 1.8 8.4 17.1 2.6 7.9 0.2 3.3 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING DNA_RNApol_7kD PF03604.8 EIW78375.1 - 3 7.3 11.0 0.18 11.3 1.1 2.9 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Prok-RING_4 PF14447.1 EIW78375.1 - 3.8 7.1 10.9 0.034 13.6 1.3 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 PHD PF00628.24 EIW78376.1 - 9.2e-09 34.8 0.1 1.8e-08 33.9 0.1 1.5 1 0 0 1 1 1 1 PHD-finger Chromo PF00385.19 EIW78376.1 - 0.0046 16.6 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PHD_2 PF13831.1 EIW78376.1 - 0.0062 15.8 1.2 0.012 14.9 0.8 1.5 1 0 0 1 1 1 1 PHD-finger DUF3813 PF12758.2 EIW78376.1 - 0.037 14.1 0.8 0.14 12.3 0.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3813) Fib_alpha PF08702.5 EIW78376.1 - 0.069 13.2 2.1 0.14 12.2 1.5 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Sec20 PF03908.8 EIW78377.1 - 1e-16 60.4 1.8 1e-16 60.4 1.3 2.4 3 1 0 3 3 3 1 Sec20 SPX PF03105.14 EIW78377.1 - 0.17 11.6 1.8 0.24 11.1 1.3 1.2 1 0 0 1 1 1 0 SPX domain TcdB_toxin_midC PF12255.3 EIW78378.1 - 0.029 14.0 2.4 0.22 11.1 0.1 2.5 2 0 0 2 2 2 0 Insecticide toxin TcdB middle/C-terminal region RNA_pol_Rpb1_7 PF04990.7 EIW78378.1 - 0.046 13.4 1.3 0.11 12.2 0.6 1.9 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 7 Glyco_hydro_47 PF01532.15 EIW78379.1 - 6.4e-129 430.5 0.5 7.5e-129 430.3 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.9 EIW78379.1 - 5.1e-07 29.4 7.2 0.0053 16.1 0.0 3.5 4 0 0 4 4 4 3 Glycosyl hydrolase family 76 LANC_like PF05147.8 EIW78379.1 - 0.001 17.7 0.3 0.16 10.5 0.0 2.6 2 1 0 2 2 2 2 Lanthionine synthetase C-like protein C5-epim_C PF06662.8 EIW78379.1 - 0.02 14.1 0.1 0.02 14.1 0.1 2.7 4 0 0 4 4 4 0 D-glucuronyl C5-epimerase C-terminus DUF1793 PF08760.6 EIW78379.1 - 0.031 14.1 0.5 0.084 12.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1793) Ribophorin_II PF05817.9 EIW78380.1 - 3.2e-31 108.2 0.0 3.9e-31 107.9 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II PCI PF01399.22 EIW78381.1 - 6.1e-21 74.7 0.2 2.7e-20 72.6 0.0 2.1 2 0 0 2 2 2 1 PCI domain Rpn3_C PF08375.6 EIW78381.1 - 7.7e-17 61.4 2.5 8.3e-17 61.3 0.1 2.2 2 0 0 2 2 2 1 Proteasome regulatory subunit C-terminal TPR_2 PF07719.12 EIW78381.1 - 0.022 14.6 3.2 0.088 12.7 0.3 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIW78381.1 - 0.041 13.8 5.5 3 7.8 2.4 3.0 1 1 0 2 2 2 0 Tetratricopeptide repeat Sigma70_r1_2 PF00140.15 EIW78381.1 - 0.13 11.9 0.7 0.33 10.6 0.5 1.6 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 TPR_16 PF13432.1 EIW78381.1 - 2.1 9.0 9.8 5.2 7.8 0.2 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat LIM PF00412.17 EIW78383.1 - 3.1e-30 103.9 22.4 8.1e-16 57.8 1.8 4.3 4 0 0 4 4 4 3 LIM domain XPG_I PF00867.13 EIW78384.1 - 9.9e-18 64.0 0.1 4.4e-17 61.9 0.1 2.2 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EIW78384.1 - 3.9e-07 30.2 0.0 1.5e-06 28.4 0.0 2.1 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 EIW78384.1 - 0.0014 18.7 3.2 0.0015 18.7 0.0 2.6 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold TFIIA PF03153.8 EIW78384.1 - 0.029 14.2 27.1 0.046 13.6 18.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MIP-T3 PF10243.4 EIW78384.1 - 0.44 8.9 52.8 0.0042 15.6 29.0 2.0 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 PAT1 PF09770.4 EIW78384.1 - 2.4 6.3 39.4 3.2 5.8 27.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 EIW78384.1 - 5.1 5.1 44.7 7 4.7 31.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Coatomer_WDAD PF04053.9 EIW78385.1 - 3.7e-142 474.2 0.0 1.5e-141 472.1 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.6 EIW78385.1 - 3.8e-94 315.6 0.0 5.8e-94 315.0 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EIW78385.1 - 4.6e-58 191.1 10.1 1.7e-10 40.3 0.2 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat TPR_2 PF07719.12 EIW78385.1 - 0.0045 16.8 1.1 0.68 9.9 0.1 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIW78385.1 - 0.01 16.4 2.1 0.56 10.9 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIW78385.1 - 0.31 10.7 1.8 7.3 6.3 0.1 2.6 2 0 0 2 2 2 0 TPR repeat TPR_14 PF13428.1 EIW78385.1 - 0.35 11.6 7.4 1.1 10.0 1.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Afi1 PF07792.7 EIW78386.1 - 3.2e-38 130.9 0.0 9.9e-38 129.4 0.0 1.9 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EIW78386.1 - 4.4e-29 100.4 0.0 8.9e-29 99.4 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EIW78386.1 - 0.00014 20.5 0.0 0.0078 14.7 0.0 2.9 2 1 1 3 3 3 1 Transport protein Avl9 DUF2347 PF09804.4 EIW78386.1 - 0.0083 15.4 0.0 1.3 8.2 0.0 2.5 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2347) DUF3594 PF12165.3 EIW78387.1 - 0.012 15.2 0.3 3.2 7.3 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3594) DUF504 PF04457.7 EIW78388.1 - 3.7e-10 39.8 0.2 8.7e-10 38.6 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF504) DARPP-32 PF05395.7 EIW78388.1 - 0.01 16.0 0.7 0.014 15.5 0.5 1.2 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 IncA PF04156.9 EIW78388.1 - 0.05 13.1 1.2 0.07 12.7 0.8 1.1 1 0 0 1 1 1 0 IncA protein NAC PF01849.13 EIW78389.1 - 2.9e-17 61.9 0.2 1.9e-13 49.7 0.1 2.3 2 0 0 2 2 2 2 NAC domain Cofilin_ADF PF00241.15 EIW78390.1 - 2.5e-21 75.8 0.2 2.8e-21 75.7 0.1 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Neugrin PF06413.6 EIW78391.1 - 2.9e-13 50.1 0.1 3.3e-13 49.9 0.1 1.0 1 0 0 1 1 1 1 Neugrin MRP-L20 PF12824.2 EIW78391.1 - 2e-05 24.6 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 HTH_23 PF13384.1 EIW78391.1 - 0.0079 15.8 0.0 0.048 13.3 0.0 1.9 2 0 0 2 2 2 1 Homeodomain-like domain MarR_2 PF12802.2 EIW78391.1 - 0.03 13.9 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 MarR family HTH_Tnp_ISL3 PF13542.1 EIW78391.1 - 0.074 12.2 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_24 PF13412.1 EIW78391.1 - 0.083 12.2 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding FeoC PF09012.5 EIW78391.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 FeoC like transcriptional regulator HTH_28 PF13518.1 EIW78391.1 - 0.13 12.3 0.0 0.68 10.0 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain p450 PF00067.17 EIW78392.1 - 7.5e-35 120.3 0.0 9.8e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 HlyIII PF03006.15 EIW78393.1 - 3.3e-47 160.7 20.5 4.7e-45 153.7 14.2 2.1 1 1 0 1 1 1 1 Haemolysin-III related DUF3483 PF11982.3 EIW78393.1 - 0.0057 15.9 1.0 0.008 15.4 0.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3483) DUF3493 PF11998.3 EIW78393.1 - 1.9 8.4 5.1 4.9 7.1 0.9 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3493) CLTH PF10607.4 EIW78394.1 - 1.4e-31 109.1 2.6 1.9e-31 108.7 1.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EIW78394.1 - 0.0021 17.7 0.0 0.0055 16.3 0.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger PIG-S PF10510.4 EIW78395.1 - 1.8e-120 403.0 3.3 6.5e-108 361.6 0.3 2.0 1 1 1 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein Rotamase PF00639.16 EIW78397.1 - 2.3e-19 69.9 0.0 3.9e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EIW78397.1 - 3.3e-19 69.2 0.0 5e-19 68.6 0.0 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EIW78397.1 - 1.1e-06 29.2 0.0 1.6e-06 28.7 0.0 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain ABC_tran PF00005.22 EIW78399.1 - 5e-33 114.3 0.1 4e-17 62.7 0.0 2.9 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIW78399.1 - 1.5e-13 51.3 4.7 0.002 18.1 0.0 4.5 2 2 2 4 4 4 4 AAA domain SMC_N PF02463.14 EIW78399.1 - 3e-10 39.6 6.7 0.0014 17.9 0.1 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain NACHT PF05729.7 EIW78399.1 - 1.9e-05 24.4 1.2 0.0074 15.9 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA PF00004.24 EIW78399.1 - 2.6e-05 24.4 0.0 0.23 11.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIW78399.1 - 3e-05 24.8 0.3 0.098 13.4 0.1 2.7 2 2 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIW78399.1 - 4.4e-05 23.6 0.0 0.065 13.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EIW78399.1 - 5.6e-05 22.3 0.0 0.13 11.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 EIW78399.1 - 7.1e-05 22.0 3.0 4.9 6.0 0.2 4.7 4 1 1 5 5 5 0 AAA ATPase domain Miro PF08477.8 EIW78399.1 - 7.6e-05 23.1 0.3 0.032 14.7 0.0 3.2 5 0 0 5 5 2 1 Miro-like protein AAA_33 PF13671.1 EIW78399.1 - 7.8e-05 22.5 0.0 0.18 11.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EIW78399.1 - 0.00017 21.4 0.1 0.88 9.5 0.0 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EIW78399.1 - 0.00095 19.4 0.1 0.21 11.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EIW78399.1 - 0.0019 17.6 2.0 0.36 10.2 0.0 2.3 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain RNA_helicase PF00910.17 EIW78399.1 - 0.0023 18.1 0.0 2.6 8.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase VirE PF05272.6 EIW78399.1 - 0.0031 17.0 0.0 1.3 8.4 0.0 2.6 2 0 0 2 2 2 1 Virulence-associated protein E AAA_29 PF13555.1 EIW78399.1 - 0.0033 16.9 1.8 1.8 8.1 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_5 PF07728.9 EIW78399.1 - 0.0056 16.4 1.2 0.26 11.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) MobB PF03205.9 EIW78399.1 - 0.0057 16.3 1.7 2.5 7.7 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EIW78399.1 - 0.0069 16.3 1.5 0.47 10.4 0.0 2.6 2 2 0 2 2 2 1 AAA ATPase domain UPF0079 PF02367.12 EIW78399.1 - 0.009 15.6 1.3 0.089 12.4 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activ_2 PF14532.1 EIW78399.1 - 0.0094 16.0 0.0 0.024 14.6 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_28 PF13521.1 EIW78399.1 - 0.0098 15.8 0.1 1.9 8.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EIW78399.1 - 0.01 15.2 0.8 4.5 6.6 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EIW78399.1 - 0.013 15.8 4.0 0.093 13.0 0.0 2.5 2 1 0 2 2 2 0 AAA domain Rad17 PF03215.10 EIW78399.1 - 0.032 12.9 0.0 0.41 9.2 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_13 PF13166.1 EIW78399.1 - 0.04 12.3 2.0 0.11 10.9 0.0 2.4 3 0 0 3 3 3 0 AAA domain Thymidylate_kin PF02223.12 EIW78399.1 - 0.048 13.0 0.3 2.8 7.2 0.0 2.8 3 0 0 3 3 3 0 Thymidylate kinase AAA_24 PF13479.1 EIW78399.1 - 0.094 12.2 1.1 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EIW78399.1 - 0.15 11.6 0.4 4 6.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EIW78399.1 - 0.26 11.1 2.6 15 5.4 0.1 3.4 2 2 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EIW78399.1 - 1.2 8.7 3.2 23 4.6 0.1 3.0 4 0 0 4 4 2 0 NTPase CUE PF02845.11 EIW78400.1 - 0.037 13.5 0.1 0.4 10.2 0.1 2.5 1 1 0 1 1 1 0 CUE domain DNA_pol_phi PF04931.8 EIW78400.1 - 6.3 4.4 12.3 11 3.5 8.5 1.3 1 0 0 1 1 1 0 DNA polymerase phi PX PF00787.19 EIW78401.1 - 3.7e-19 68.5 0.0 1.1e-18 67.0 0.0 1.8 1 1 0 1 1 1 1 PX domain BAR_3_WASP_bdg PF10456.4 EIW78401.1 - 1.3e-17 63.8 0.8 4.3e-16 58.8 0.6 2.1 2 0 0 2 2 2 1 WASP-binding domain of Sorting nexin protein SH3_1 PF00018.23 EIW78401.1 - 0.00028 20.2 0.0 0.00051 19.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Aldo_ket_red PF00248.16 EIW78402.1 - 6.7e-68 228.5 0.0 7.6e-68 228.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EIW78403.1 - 2.6e-44 151.1 0.0 3.1e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Dimer_Tnp_hAT PF05699.9 EIW78404.1 - 2.4e-10 39.9 0.3 2.6e-10 39.7 0.2 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region AAA_16 PF13191.1 EIW78405.1 - 0.09 12.7 0.0 2 8.3 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.1 EIW78405.1 - 0.12 12.5 0.0 0.46 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain TFIIE_alpha PF02002.12 EIW78414.1 - 4.4e-19 67.9 0.1 1e-18 66.7 0.1 1.6 1 0 0 1 1 1 1 TFIIE alpha subunit TF_Zn_Ribbon PF08271.7 EIW78414.1 - 1.1e-05 24.5 1.2 2.5e-05 23.5 0.9 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding TFIIE-A_C-term PF11521.3 EIW78414.1 - 0.0098 15.8 1.8 0.0098 15.8 1.2 1.9 2 0 0 2 2 2 1 C-terminal general transcription factor TFIIE alpha Gin PF10764.4 EIW78414.1 - 0.013 15.1 1.5 3.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin DZR PF12773.2 EIW78414.1 - 0.13 12.0 0.4 0.3 10.9 0.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2_6 PF13912.1 EIW78414.1 - 0.23 11.4 1.5 0.24 11.3 0.1 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger PhnA_Zn_Ribbon PF08274.7 EIW78414.1 - 0.36 10.6 3.5 1.2 8.9 2.4 1.8 1 1 0 1 1 1 0 PhnA Zinc-Ribbon NmrA PF05368.8 EIW78415.1 - 2.1e-40 138.4 0.0 2.5e-40 138.1 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIW78415.1 - 3.8e-14 53.1 0.0 6.4e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIW78415.1 - 0.00061 18.5 0.0 0.00099 17.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EIW78415.1 - 0.00075 19.4 0.1 0.0029 17.5 0.0 2.0 3 0 0 3 3 3 1 TrkA-N domain LRR_6 PF13516.1 EIW78417.1 - 3e-07 29.8 11.1 0.42 10.8 0.1 5.9 6 0 0 6 6 6 3 Leucine Rich repeat LRR_4 PF12799.2 EIW78417.1 - 0.00024 20.6 3.0 0.016 14.8 0.0 3.4 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIW78417.1 - 0.0082 16.0 4.5 6.5 7.2 0.0 5.1 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_7 PF13504.1 EIW78417.1 - 5.2 7.7 11.3 6.7 7.3 0.1 4.8 6 0 0 6 6 6 0 Leucine rich repeat DBR1 PF05011.8 EIW78418.1 - 8.5e-29 100.2 0.0 3e-27 95.2 0.0 2.3 1 1 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EIW78418.1 - 5.1e-10 39.0 3.9 7.3e-10 38.5 2.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIW78418.1 - 0.00021 21.1 0.0 0.00043 20.1 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF720 PF05302.6 EIW78418.1 - 0.061 13.0 0.1 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF720) PIG-L PF02585.12 EIW78420.1 - 2e-20 73.5 0.0 6.3e-20 71.9 0.0 1.8 2 0 0 2 2 2 1 GlcNAc-PI de-N-acetylase DUF1770 PF08589.5 EIW78421.1 - 1.3e-06 28.9 0.1 2.4e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) DUF3455 PF11937.3 EIW78422.1 - 2e-21 76.6 0.2 2.9e-21 76.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Peptidase_C14 PF00656.17 EIW78423.1 - 1.2e-21 77.5 0.0 1.3e-21 77.4 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.17 EIW78424.1 - 1.1e-22 80.9 0.0 2e-22 80.0 0.0 1.4 1 1 0 1 1 1 1 Caspase domain Peptidase_C13 PF01650.13 EIW78424.1 - 0.0082 15.4 0.1 4.3 6.5 0.0 3.2 2 1 1 3 3 3 2 Peptidase C13 family Nup96 PF12110.3 EIW78425.1 - 5.9e-73 245.5 0.0 8.8e-73 244.9 0.0 1.3 1 0 0 1 1 1 1 Nuclear protein 96 UQ_con PF00179.21 EIW78428.1 - 1.2e-51 173.7 0.0 1.4e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIW78428.1 - 0.00028 20.6 0.0 0.00033 20.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EIW78428.1 - 0.0035 17.2 0.0 0.004 17.0 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EIW78428.1 - 0.034 13.8 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 UEV domain G-patch PF01585.18 EIW78429.1 - 1.5e-06 27.8 0.6 3.9e-06 26.5 0.4 1.7 1 0 0 1 1 1 1 G-patch domain Ndufs5 PF10200.4 EIW78430.1 - 3e-05 23.9 0.5 3.8e-05 23.5 0.3 1.2 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Cmc1 PF08583.5 EIW78430.1 - 0.0007 19.3 1.9 0.001 18.7 1.3 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EIW78430.1 - 0.003 17.4 3.5 0.0073 16.1 2.4 1.6 1 1 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EIW78430.1 - 0.017 15.1 1.0 0.025 14.6 0.7 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 DUF3128 PF11326.3 EIW78430.1 - 0.02 14.9 3.2 0.049 13.7 2.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3128) PADR1 PF08063.7 EIW78430.1 - 0.65 9.4 3.9 9.7 5.6 0.0 2.5 2 1 1 3 3 3 0 PADR1 (NUC008) domain COX6B PF02297.12 EIW78430.1 - 2.5 8.1 7.2 1.4 8.9 0.3 2.1 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb ubiquitin PF00240.18 EIW78431.1 - 1.5e-15 56.3 0.0 2.5e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EIW78431.1 - 3.2e-09 36.3 0.1 6.6e-09 35.3 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like CLU_N PF15044.1 EIW78431.1 - 0.023 14.8 0.0 0.057 13.5 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial function, CLU-N-term Glyco_transf_25 PF01755.12 EIW78432.1 - 1.3e-19 70.6 0.1 2.2e-10 40.5 0.1 3.1 2 1 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) GST_N_2 PF13409.1 EIW78433.1 - 1.2e-20 73.2 0.0 2.4e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW78433.1 - 5.9e-16 58.1 0.0 1.3e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW78433.1 - 6.6e-10 38.8 0.0 1.2e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW78433.1 - 5.5e-06 26.7 0.0 1e-05 25.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIW78433.1 - 2.5e-05 24.4 0.1 0.0014 18.7 0.0 2.6 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain p450 PF00067.17 EIW78435.1 - 1.2e-73 248.1 0.0 2.9e-73 246.9 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 3-alpha PF03475.9 EIW78438.1 - 0.36 10.5 2.4 4.3 7.1 0.1 2.9 3 0 0 3 3 3 0 3-alpha domain PYNP_C PF07831.8 EIW78439.1 - 0.054 12.9 0.2 0.11 11.9 0.1 1.5 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain DUF2380 PF09533.5 EIW78439.1 - 0.055 12.8 0.3 0.083 12.2 0.2 1.3 1 0 0 1 1 1 0 Predicted lipoprotein of unknown function (DUF2380) RRM_1 PF00076.17 EIW78440.1 - 1.4e-30 104.7 0.0 1.9e-15 56.2 0.0 2.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW78440.1 - 1.8e-23 82.2 0.0 4.3e-12 45.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW78440.1 - 5.5e-06 26.1 0.0 0.0081 15.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_1 PF00583.19 EIW78440.1 - 0.0069 16.3 0.1 0.11 12.5 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family DUF1918 PF08940.6 EIW78440.1 - 0.036 13.3 0.2 1.7 8.0 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1918) ERG2_Sigma1R PF04622.7 EIW78441.1 - 1.8e-82 275.7 0.4 3.8e-82 274.7 0.3 1.4 1 1 0 1 1 1 1 ERG2 and Sigma1 receptor like protein Histone PF00125.19 EIW78442.1 - 8.5e-22 77.0 0.3 1.3e-21 76.4 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIW78442.1 - 5.5e-05 23.1 0.1 5.5e-05 23.1 0.1 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EIW78442.1 - 0.00023 21.4 0.1 0.00053 20.2 0.0 1.6 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A Mitofilin PF09731.4 EIW78442.1 - 0.032 12.8 4.1 0.041 12.5 2.8 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DUF1018 PF06252.7 EIW78442.1 - 0.043 14.3 1.1 0.07 13.6 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1018) RP-C PF03428.8 EIW78442.1 - 0.052 12.9 0.9 0.12 11.8 0.6 1.7 1 1 0 1 1 1 0 Replication protein C N-terminal domain Histone PF00125.19 EIW78443.1 - 1.5e-26 92.2 0.0 1.9e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIW78443.1 - 1.5e-06 28.1 0.0 2.2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Amino_oxidase PF01593.19 EIW78446.1 - 8.9e-19 67.8 0.4 8.8e-18 64.6 0.3 2.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EIW78446.1 - 4.8e-13 48.7 0.5 2.4e-10 39.8 0.0 3.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW78446.1 - 3.8e-12 46.0 1.7 1.2e-10 41.3 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIW78446.1 - 4.6e-06 26.9 1.9 0.18 12.2 0.0 4.0 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW78446.1 - 6e-05 23.2 0.1 1.3 9.0 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW78446.1 - 0.00013 20.5 1.0 0.044 12.2 0.0 2.4 3 0 0 3 3 3 2 HI0933-like protein NAD_binding_9 PF13454.1 EIW78446.1 - 0.00033 20.4 1.3 0.25 11.1 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 EIW78446.1 - 0.00069 18.7 0.1 0.0051 15.9 0.0 2.0 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.9 EIW78446.1 - 0.017 13.7 0.0 0.025 13.2 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase K_oxygenase PF13434.1 EIW78446.1 - 0.054 12.4 0.0 1.8 7.3 0.0 2.3 3 0 0 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) SPC25 PF06703.6 EIW78447.1 - 3.9e-35 120.8 0.0 4.7e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Ribosomal_S14 PF00253.16 EIW78448.1 - 0.046 13.1 0.4 0.046 13.1 0.3 1.7 2 0 0 2 2 2 0 Ribosomal protein S14p/S29e DUF4243 PF14027.1 EIW78449.1 - 2.2e-80 270.5 0.0 2.7e-80 270.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) XPG_I PF00867.13 EIW78450.1 - 1.2e-21 76.5 0.0 2.7e-21 75.4 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EIW78450.1 - 3.3e-07 30.5 0.0 2.1e-06 27.8 0.0 2.1 1 1 0 1 1 1 1 XPG N-terminal domain DUF1517 PF07466.6 EIW78452.1 - 0.83 8.5 5.5 1.9 7.4 3.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Glyco_hydro_61 PF03443.9 EIW78453.1 - 1.9e-62 210.9 0.1 2.7e-62 210.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 PWI PF01480.12 EIW78454.1 - 3.5e-28 97.5 0.0 5.2e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 PWI domain F-box-like PF12937.2 EIW78455.1 - 0.0015 18.1 0.1 0.0027 17.3 0.1 1.4 1 0 0 1 1 1 1 F-box-like BMFP PF04380.8 EIW78455.1 - 0.057 13.5 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 Membrane fusogenic activity MR_MLE_C PF13378.1 EIW78456.1 - 7.9e-33 112.7 0.0 1.4e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 EIW78456.1 - 2.8e-21 75.6 0.0 6.6e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 EIW78456.1 - 2.3e-11 44.0 0.0 4.5e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain F-box-like PF12937.2 EIW78457.1 - 7.3e-10 38.4 0.6 3.8e-09 36.1 0.4 2.2 1 1 0 1 1 1 1 F-box-like EMP24_GP25L PF01105.19 EIW78458.1 - 4.5e-41 140.5 0.0 5.1e-41 140.3 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Dus PF01207.12 EIW78459.1 - 9.6e-52 175.7 0.7 5.2e-51 173.3 0.5 2.0 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EIW78459.1 - 0.012 14.8 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein Glyco_hydro_76 PF03663.9 EIW78460.1 - 2.5e-18 66.6 27.8 1.7e-17 63.8 19.2 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Imm19 PF15567.1 EIW78461.1 - 0.032 14.2 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 19 ADH_N PF08240.7 EIW78462.1 - 8.6e-26 89.8 0.3 1.7e-25 88.8 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW78462.1 - 9.1e-26 89.9 0.0 1.7e-25 89.0 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW78462.1 - 5.7e-07 30.4 0.0 1.5e-06 29.1 0.0 1.7 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EIW78462.1 - 0.00037 21.0 0.1 0.00069 20.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain AlaDh_PNT_C PF01262.16 EIW78462.1 - 0.00096 18.7 0.1 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain PrmA PF06325.8 EIW78462.1 - 0.0018 17.4 0.0 0.0029 16.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.7 EIW78462.1 - 0.0044 17.4 0.1 0.014 15.8 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 EIW78462.1 - 0.0056 16.0 0.0 0.0082 15.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 EIW78462.1 - 0.026 13.6 0.0 0.046 12.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MTS PF05175.9 EIW78462.1 - 0.03 13.7 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain TrkA_N PF02254.13 EIW78462.1 - 0.033 14.1 0.0 0.06 13.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain OmpH PF03938.9 EIW78462.1 - 0.043 13.7 0.0 0.064 13.1 0.0 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) 3HCDH_N PF02737.13 EIW78462.1 - 0.11 12.1 0.1 0.16 11.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain YdfZ PF14001.1 EIW78462.1 - 0.54 10.5 3.1 3 8.1 0.0 3.0 4 0 0 4 4 4 0 YdfZ protein adh_short PF00106.20 EIW78463.1 - 8.1e-34 116.9 0.5 1e-33 116.6 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW78463.1 - 1.8e-25 90.1 0.0 2.4e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW78463.1 - 2.8e-18 66.2 0.2 3.8e-18 65.7 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW78463.1 - 6.3e-06 25.8 0.0 1.2e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EIW78463.1 - 6.8e-05 22.5 0.2 0.00013 21.6 0.2 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 EIW78463.1 - 0.025 13.8 0.0 0.036 13.3 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 EIW78463.1 - 0.072 11.9 0.1 0.27 10.0 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain DAO PF01266.19 EIW78463.1 - 0.11 11.4 0.3 0.16 10.8 0.2 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase ABC_tran PF00005.22 EIW78464.1 - 8.1e-48 162.2 0.0 9.4e-28 97.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIW78464.1 - 4.3e-44 150.9 21.1 8e-24 84.5 5.6 3.2 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EIW78464.1 - 1.1e-08 34.6 0.0 0.0033 16.7 0.5 3.5 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EIW78464.1 - 2.2e-05 23.9 0.1 0.1 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EIW78464.1 - 6.2e-05 22.5 0.1 0.075 12.4 0.0 2.6 2 1 0 3 3 3 2 AAA-like domain AAA_22 PF13401.1 EIW78464.1 - 0.00036 20.6 0.6 0.23 11.5 0.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EIW78464.1 - 0.00073 19.0 1.3 0.38 10.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EIW78464.1 - 0.0012 18.8 1.6 0.72 9.7 0.0 3.4 3 1 0 3 3 2 1 AAA domain T2SE PF00437.15 EIW78464.1 - 0.0019 17.1 0.0 0.025 13.4 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.1 EIW78464.1 - 0.01 15.8 0.1 0.45 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EIW78464.1 - 0.015 14.7 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF87 PF01935.12 EIW78464.1 - 0.027 14.2 0.0 0.074 12.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_23 PF13476.1 EIW78464.1 - 0.051 13.8 0.0 7.1 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EIW78464.1 - 0.21 10.6 0.5 14 4.6 0.1 2.3 2 0 0 2 2 2 0 KaiC DUF258 PF03193.11 EIW78464.1 - 0.31 10.1 0.0 7.2 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Malic_M PF03949.10 EIW78465.1 - 9.1e-85 284.2 0.0 1.2e-84 283.9 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EIW78465.1 - 7.3e-65 217.9 0.0 1e-64 217.4 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DNA_primase_S PF01896.14 EIW78466.1 - 1.4e-52 177.3 0.0 2e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit SR-25 PF10500.4 EIW78469.1 - 0.62 9.5 8.0 0.84 9.0 5.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Herpes_capsid PF06112.6 EIW78469.1 - 0.63 10.0 5.9 0.91 9.5 4.1 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Amino_oxidase PF01593.19 EIW78471.1 - 5.5e-35 121.3 0.1 3.9e-23 82.2 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EIW78471.1 - 1.1e-09 38.1 0.3 3.3e-09 36.6 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EIW78471.1 - 0.14 11.1 0.2 0.23 10.4 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EIW78471.1 - 0.15 12.0 1.2 0.63 10.0 0.2 2.3 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase 2-oxoacid_dh PF00198.18 EIW78472.1 - 3.4e-81 271.8 0.2 5.4e-81 271.2 0.1 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EIW78472.1 - 1.5e-20 72.5 1.9 2.9e-20 71.6 1.3 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_3 PF13437.1 EIW78472.1 - 0.00095 19.4 0.2 0.096 13.0 0.0 2.4 1 1 1 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 EIW78472.1 - 0.00096 18.7 0.3 0.011 15.4 0.1 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like GCV_H PF01597.14 EIW78472.1 - 0.0016 18.0 0.2 0.0038 16.9 0.2 1.6 1 0 0 1 1 1 1 Glycine cleavage H-protein HlyD_2 PF12700.2 EIW78472.1 - 0.0047 16.1 9.2 0.013 14.6 4.5 2.3 1 1 1 2 2 2 1 HlyD family secretion protein Ribosomal_60s PF00428.14 EIW78472.1 - 0.76 10.2 25.2 0.16 12.3 4.5 3.1 1 1 1 2 2 2 0 60s Acidic ribosomal protein AflR PF08493.5 EIW78472.1 - 1.2 8.1 4.3 0.76 8.7 0.0 2.4 1 1 1 2 2 2 0 Aflatoxin regulatory protein TLP-20 PF06088.6 EIW78472.1 - 1.3 8.6 4.4 2.3 7.8 2.9 1.5 1 1 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) WD40 PF00400.27 EIW78473.1 - 5.2e-14 51.5 9.0 4.1e-05 23.3 0.0 6.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Aldo_ket_red PF00248.16 EIW78474.1 - 1.2e-42 145.7 0.0 6.4e-30 103.9 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family MFS_1 PF07690.11 EIW78475.1 - 3.2e-16 58.9 44.3 1.5e-10 40.3 12.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIW78475.1 - 0.00012 20.6 8.9 0.00012 20.6 6.2 2.6 2 1 1 3 3 3 2 MFS/sugar transport protein DUF4112 PF13430.1 EIW78475.1 - 1.6 8.6 7.7 1.9 8.4 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4112) DUF1228 PF06779.9 EIW78475.1 - 2.9 7.9 17.2 3.7 7.6 0.1 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) DUF2917 PF11142.3 EIW78476.1 - 0.15 11.2 0.1 0.22 10.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2917) SAYSvFN PF10260.4 EIW78477.1 - 0.15 11.8 1.0 4.1 7.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) zf-DHHC PF01529.15 EIW78477.1 - 7 6.0 6.1 7.2 5.9 3.6 1.4 1 1 0 1 1 1 0 DHHC palmitoyltransferase MerC PF03203.9 EIW78478.1 - 3.9 7.8 7.7 2 8.7 0.7 2.5 2 0 0 2 2 2 0 MerC mercury resistance protein Sec23_trunk PF04811.10 EIW78479.1 - 2.2e-68 230.2 0.0 3.4e-68 229.6 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EIW78479.1 - 4.3e-23 80.7 0.1 8.2e-23 79.8 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EIW78479.1 - 3.2e-16 59.6 0.1 7.9e-16 58.3 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EIW78479.1 - 1.3e-15 56.6 7.9 2.2e-15 55.9 5.5 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EIW78479.1 - 2.7e-06 26.9 0.1 7.9e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat WW PF00397.21 EIW78479.1 - 0.0001 22.0 3.5 0.0001 22.0 2.4 2.4 2 0 0 2 2 2 1 WW domain ATP-synt_10 PF05176.9 EIW78480.1 - 4.2e-67 226.0 0.0 5.3e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein Histone PF00125.19 EIW78481.1 - 1.6e-26 92.2 0.0 2e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIW78481.1 - 1.7e-06 28.0 0.0 2.2e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Aldo_ket_red PF00248.16 EIW78482.1 - 3.5e-76 255.7 0.0 4e-76 255.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MFS_1 PF07690.11 EIW78483.1 - 3.2e-20 72.1 49.0 4.3e-17 61.8 15.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIW78483.1 - 3.3e-05 22.4 10.8 3.3e-05 22.4 7.5 2.6 1 1 1 2 2 2 1 MFS/sugar transport protein DUF1228 PF06779.9 EIW78483.1 - 0.18 11.8 0.1 0.18 11.8 0.1 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) MFS_1 PF07690.11 EIW78485.1 - 2.7e-21 75.6 28.0 9.7e-15 54.1 5.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ELYS PF13934.1 EIW78486.1 - 5.7e-45 153.8 0.0 1.2e-44 152.7 0.0 1.5 2 0 0 2 2 2 1 Nuclear pore complex assembly Mac PF12464.3 EIW78486.1 - 0.08 12.9 0.0 2.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Maltose acetyltransferase PITH PF06201.8 EIW78487.1 - 2e-35 121.8 0.0 2.5e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain Ribosomal_S5_C PF03719.10 EIW78488.1 - 1.1e-18 66.2 0.2 3.3e-18 64.7 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EIW78488.1 - 5.5e-18 64.4 0.1 5.4e-17 61.2 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EIW78489.1 - 5.1e-19 67.3 0.1 2e-18 65.4 0.0 2.0 3 0 0 3 3 3 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EIW78489.1 - 6.3e-17 61.0 0.7 6e-16 57.9 0.2 2.2 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Pkinase PF00069.20 EIW78490.1 - 4.3e-49 167.0 0.0 5e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW78490.1 - 2.1e-22 79.4 0.0 2.4e-22 79.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EIW78490.1 - 6.8e-05 21.8 0.0 0.00018 20.4 0.0 1.6 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase APH PF01636.18 EIW78490.1 - 0.0014 18.4 0.1 0.0026 17.5 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF959 PF06121.9 EIW78491.1 - 0.56 9.8 16.6 0.38 10.3 1.7 2.5 2 1 0 2 2 2 0 Domain of Unknown Function (DUF959) Transp_cyt_pur PF02133.10 EIW78492.1 - 4.3e-142 473.7 40.9 5e-142 473.5 28.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin RmlD_sub_bind PF04321.12 EIW78494.1 - 6.5e-46 156.5 0.0 7.2e-46 156.3 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EIW78494.1 - 2.8e-24 85.8 0.0 3.4e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EIW78494.1 - 2.2e-10 39.8 0.1 9.1e-09 34.6 0.0 2.5 1 1 1 2 2 2 1 Male sterility protein NAD_binding_10 PF13460.1 EIW78494.1 - 4.7e-07 30.0 0.0 7.6e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIW78494.1 - 0.00066 18.4 0.0 0.0015 17.2 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EIW78494.1 - 0.014 14.6 0.0 0.034 13.3 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family Polysacc_synt_2 PF02719.10 EIW78494.1 - 0.034 13.0 0.3 8.9 5.1 0.1 3.2 2 1 0 2 2 2 0 Polysaccharide biosynthesis protein adh_short PF00106.20 EIW78494.1 - 0.039 13.8 0.1 0.11 12.4 0.1 1.8 1 1 0 1 1 1 0 short chain dehydrogenase DapB_N PF01113.15 EIW78494.1 - 0.056 13.3 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Arrestin_N PF00339.24 EIW78495.1 - 0.00062 19.6 0.0 0.0091 15.8 0.0 2.4 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Vps16_C PF04840.7 EIW78496.1 - 7.3e-81 271.5 0.1 1e-80 271.0 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.8 EIW78496.1 - 7.5e-75 251.9 0.0 1e-74 251.5 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region HAD_2 PF13419.1 EIW78497.1 - 7.9e-26 91.3 0.0 9.6e-26 91.0 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIW78497.1 - 7.3e-08 33.0 0.0 9.4e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase EXS PF03124.9 EIW78498.1 - 1.7e-47 162.1 9.3 2.1e-47 161.8 6.4 1.0 1 0 0 1 1 1 1 EXS family DUF1673 PF07895.6 EIW78498.1 - 3.7 7.0 8.7 9.6 5.6 5.5 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) F-box-like PF12937.2 EIW78499.1 - 0.058 13.1 0.5 0.08 12.6 0.3 1.3 1 0 0 1 1 1 0 F-box-like Glutaredoxin PF00462.19 EIW78500.1 - 6.9e-16 57.9 0.1 1.8e-15 56.6 0.0 1.7 2 0 0 2 2 2 1 Glutaredoxin FF PF01846.14 EIW78500.1 - 0.041 13.8 0.0 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 FF domain Sec62 PF03839.11 EIW78501.1 - 1.4e-44 152.1 5.3 6.4e-44 150.0 2.5 1.9 2 0 0 2 2 2 2 Translocation protein Sec62 F-box-like PF12937.2 EIW78502.1 - 0.037 13.7 0.8 0.1 12.3 0.6 1.8 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.2 EIW78503.1 - 0.0004 20.0 0.9 0.00089 18.9 0.6 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIW78504.1 - 0.00015 21.3 2.3 0.00041 19.9 1.6 1.8 1 0 0 1 1 1 1 F-box-like Amidohydro_1 PF01979.15 EIW78504.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase family TPR_12 PF13424.1 EIW78505.1 - 0.00056 19.7 1.3 2.8 7.9 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIW78505.1 - 0.0012 18.6 1.7 2.5 8.2 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIW78505.1 - 0.0036 16.9 0.0 3.4 7.3 0.0 2.9 3 1 0 3 3 3 2 TPR repeat MIT PF04212.13 EIW78505.1 - 0.032 14.1 0.0 3.9 7.4 0.0 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain RTA1 PF04479.8 EIW78506.1 - 9.5e-42 143.0 7.3 1.4e-41 142.4 5.0 1.2 1 0 0 1 1 1 1 RTA1 like protein OAD_gamma PF04277.8 EIW78506.1 - 0.18 12.1 1.5 4.2 7.8 0.0 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF4131 PF13567.1 EIW78506.1 - 0.54 9.6 7.5 4.3 6.7 1.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF202 PF02656.10 EIW78506.1 - 9.4 6.5 8.8 19 5.5 0.1 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF202) Rad17 PF03215.10 EIW78507.1 - 7.6e-47 160.1 0.0 1.7e-22 79.8 0.0 3.3 3 0 0 3 3 3 3 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EIW78507.1 - 0.0084 16.1 1.0 0.2 11.6 0.7 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EIW78507.1 - 0.016 15.4 0.0 0.042 14.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CHCH PF06747.8 EIW78508.1 - 0.00081 19.2 1.7 0.0017 18.2 1.2 1.5 1 1 0 1 1 1 1 CHCH domain DUF2076 PF09849.4 EIW78508.1 - 0.0025 17.9 0.2 0.0028 17.7 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) zinc-ribbons_6 PF07191.7 EIW78508.1 - 0.048 13.4 3.6 0.062 13.1 2.5 1.2 1 0 0 1 1 1 0 zinc-ribbons Pyocin_S PF06958.7 EIW78509.1 - 1.2 9.5 9.9 3.2 8.1 2.2 2.7 2 0 0 2 2 2 0 S-type Pyocin DUF1449 PF07290.6 EIW78510.1 - 0.023 14.0 1.0 0.22 10.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1449) Gly_transf_sug PF04488.10 EIW78511.1 - 2.6e-06 27.7 0.0 4e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EIW78511.1 - 0.12 11.5 0.6 0.18 10.9 0.4 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein F-box-like PF12937.2 EIW78520.1 - 0.027 14.2 0.1 0.1 12.3 0.0 2.1 2 0 0 2 2 2 0 F-box-like Cation_efflux PF01545.16 EIW78521.1 - 0.61 9.1 3.5 2.2 7.2 0.9 2.1 1 1 1 2 2 2 0 Cation efflux family DUF4131 PF13567.1 EIW78521.1 - 2.8 7.3 6.5 3.5 6.9 0.7 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) WW PF00397.21 EIW78522.1 - 0.074 12.9 0.1 0.074 12.9 0.1 2.4 2 0 0 2 2 2 0 WW domain DUF4013 PF13197.1 EIW78522.1 - 0.1 11.9 0.1 0.16 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4013) adh_short PF00106.20 EIW78523.1 - 1.3e-25 90.2 3.0 6.5e-25 87.9 0.9 2.0 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW78523.1 - 1.3e-22 80.7 0.0 1.5e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW78523.1 - 4.1e-18 65.6 0.6 4.1e-18 65.6 0.4 1.5 2 0 0 2 2 2 1 KR domain ELFV_dehydrog PF00208.16 EIW78523.1 - 0.0029 17.2 0.0 0.0051 16.4 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF1776 PF08643.5 EIW78523.1 - 0.11 11.6 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Glyco_transf_5 PF08323.6 EIW78523.1 - 0.14 11.6 0.0 2.9 7.3 0.0 2.2 2 0 0 2 2 2 0 Starch synthase catalytic domain DEAD PF00270.24 EIW78524.1 - 5.6e-41 139.8 0.2 9.1e-41 139.1 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW78524.1 - 6.7e-24 83.5 0.1 1.6e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EIW78524.1 - 0.11 11.5 0.1 0.26 10.3 0.1 1.6 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit F-box-like PF12937.2 EIW78525.1 - 6.8e-10 38.5 2.3 6.8e-10 38.5 1.6 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIW78525.1 - 0.096 12.3 8.3 2.8 7.7 0.0 4.0 4 0 0 4 4 4 0 F-box domain LRR_8 PF13855.1 EIW78525.1 - 0.31 10.8 1.5 6.1 6.6 0.0 2.9 3 0 0 3 3 3 0 Leucine rich repeat DUF2803 PF10972.3 EIW78527.1 - 0.11 12.0 1.9 0.6 9.5 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2803) Shisa PF13908.1 EIW78529.1 - 0.074 13.2 0.0 0.14 12.3 0.0 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator WD40 PF00400.27 EIW78530.1 - 1.1e-52 174.0 18.5 1.9e-10 40.2 0.0 12.2 12 0 0 12 12 12 8 WD domain, G-beta repeat Utp12 PF04003.7 EIW78530.1 - 5.3e-25 87.4 0.0 8e-25 86.8 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family PQQ_2 PF13360.1 EIW78530.1 - 4.5e-06 26.3 3.5 0.38 10.1 0.6 4.3 3 1 1 4 4 4 3 PQQ-like domain eIF2A PF08662.6 EIW78530.1 - 4.7e-05 23.1 0.7 0.86 9.2 0.0 5.1 3 2 3 6 6 6 1 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EIW78530.1 - 5.5e-05 21.6 0.3 0.69 8.1 0.0 4.0 4 0 0 4 4 4 2 Cytochrome D1 heme domain PD40 PF07676.7 EIW78530.1 - 0.0027 17.3 6.0 13 5.6 0.0 6.5 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 EIW78530.1 - 0.0048 15.5 0.0 1.6 7.2 0.0 3.6 3 1 1 4 4 4 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region IKI3 PF04762.7 EIW78530.1 - 0.049 11.4 0.0 12 3.5 0.0 3.3 2 1 1 3 3 3 0 IKI3 family DUF1513 PF07433.6 EIW78530.1 - 0.051 12.4 0.1 18 4.0 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1513) TFIIIC_delta PF12657.2 EIW78530.1 - 0.061 13.0 0.0 12 5.5 0.0 4.0 4 1 1 5 5 5 0 Transcription factor IIIC subunit delta N-term RAB3GAP2_N PF14655.1 EIW78530.1 - 0.1 11.6 0.1 1.3 7.9 0.0 2.8 4 0 0 4 4 4 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ PF01011.16 EIW78530.1 - 0.11 12.0 0.2 29 4.4 0.0 3.6 3 0 0 3 3 2 0 PQQ enzyme repeat Proteasome_A_N PF10584.4 EIW78530.1 - 0.13 11.5 0.9 23 4.4 0.0 3.5 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature DUF3810 PF12725.2 EIW78531.1 - 5.6 5.7 9.7 0.49 9.2 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Gly_transf_sug PF04488.10 EIW78532.1 - 0.00027 21.2 0.0 0.00048 20.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif F-box-like PF12937.2 EIW78533.1 - 0.00068 19.3 0.1 0.0023 17.6 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIW78534.1 - 0.00021 20.9 0.0 0.00067 19.3 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_7 PF13504.1 EIW78534.1 - 0.14 12.4 2.3 35 5.2 0.0 4.9 4 0 0 4 4 4 0 Leucine rich repeat MLTD_N PF06474.7 EIW78535.1 - 0.72 10.0 3.2 2.9 8.1 0.0 2.7 3 0 0 3 3 3 0 MltD lipid attachment motif Matrilin_ccoil PF10393.4 EIW78536.1 - 0.013 14.8 1.2 0.029 13.7 0.8 1.6 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin MRP-L51 PF10244.4 EIW78536.1 - 0.036 14.0 1.1 0.5 10.4 0.1 2.5 1 1 0 2 2 2 0 Mitochondrial ribosomal subunit NolV PF06635.7 EIW78536.1 - 0.038 13.1 0.5 0.067 12.3 0.4 1.4 1 0 0 1 1 1 0 Nodulation protein NolV DUF2408 PF10303.4 EIW78536.1 - 0.062 13.4 6.7 0.041 14.0 3.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) GIT1_C PF12205.3 EIW78536.1 - 0.18 11.6 2.0 0.4 10.5 0.4 2.2 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term DUF948 PF06103.6 EIW78536.1 - 0.2 11.5 2.5 1.1 9.1 0.1 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Phage_GP20 PF06810.6 EIW78536.1 - 0.31 10.4 11.9 0.49 9.8 1.5 2.7 3 0 0 3 3 3 0 Phage minor structural protein GP20 ORF6C PF10552.4 EIW78536.1 - 0.55 9.9 7.5 1.3 8.7 5.2 1.7 1 0 0 1 1 1 0 ORF6C domain CENP-Q PF13094.1 EIW78536.1 - 2 8.4 18.0 0.37 10.8 8.8 2.3 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Syntaxin-6_N PF09177.6 EIW78536.1 - 5.8 7.4 13.5 5.3 7.5 2.6 3.9 3 1 0 3 3 3 0 Syntaxin 6, N-terminal Muted PF14942.1 EIW78536.1 - 8.8 6.2 14.8 0.35 10.7 4.7 2.5 2 1 0 3 3 3 0 Organelle biogenesis, Muted-like protein Pkinase PF00069.20 EIW78539.1 - 2.5e-68 230.0 0.0 3e-68 229.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW78539.1 - 1.7e-27 96.1 0.0 2.7e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW78539.1 - 1.5e-06 27.4 0.0 2.4e-06 26.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIW78539.1 - 0.0012 17.8 0.0 0.0022 17.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EIW78539.1 - 0.0017 17.7 0.0 0.0036 16.6 0.0 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EIW78539.1 - 0.0022 17.7 0.2 1.1 8.9 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family TcdB_toxin_midN PF12256.3 EIW78539.1 - 0.053 12.9 0.0 0.093 12.1 0.0 1.3 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region NTF2 PF02136.15 EIW78540.1 - 2e-26 92.7 0.1 3e-26 92.0 0.1 1.3 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EIW78540.1 - 6.2e-06 25.7 0.0 1.2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW78540.1 - 1.8e-05 24.4 0.0 3.7e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW78540.1 - 0.00019 21.3 0.0 0.00038 20.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Het-C PF07217.6 EIW78541.1 - 9e-222 737.5 0.0 1.1e-221 737.2 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C AAA_22 PF13401.1 EIW78543.1 - 0.026 14.6 0.0 0.15 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain DEAD PF00270.24 EIW78544.1 - 1.7e-33 115.5 0.0 3.5e-32 111.2 0.0 2.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW78544.1 - 3e-23 81.4 0.0 1.4e-22 79.3 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW78544.1 - 0.00028 20.7 0.0 0.0013 18.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIW78544.1 - 0.11 12.6 0.5 3.2 7.8 0.0 2.8 3 0 0 3 3 3 0 AAA domain F-box-like PF12937.2 EIW78545.1 - 0.01 15.5 0.0 0.042 13.5 0.0 2.1 1 1 0 1 1 1 1 F-box-like Terpene_synth_C PF03936.11 EIW78546.1 - 5.2e-18 65.2 0.0 6.6e-18 64.8 0.0 1.3 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain MFS_1 PF07690.11 EIW78548.1 - 3.2e-23 82.0 25.0 1.1e-20 73.6 2.4 2.8 3 0 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW78548.1 - 4.7e-06 25.4 9.8 4.7e-06 25.4 6.8 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter DUF2408 PF10303.4 EIW78549.1 - 0.0013 18.8 0.9 0.0013 18.8 0.6 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2408) V_ATPase_I PF01496.14 EIW78549.1 - 0.079 10.8 4.7 0.12 10.2 3.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.17 EIW78549.1 - 0.94 9.5 18.0 0.22 11.5 0.5 4.3 3 1 0 4 4 4 0 Seryl-tRNA synthetase N-terminal domain ApoLp-III PF07464.6 EIW78549.1 - 1.9 8.5 14.3 1.1 9.2 0.4 3.2 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF1048 PF06304.6 EIW78549.1 - 3 8.2 6.6 0.64 10.3 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1048) OEP PF02321.13 EIW78549.1 - 3.2 7.3 12.3 0.55 9.7 2.1 2.8 2 0 0 2 2 2 0 Outer membrane efflux protein Tox-SHH PF15652.1 EIW78549.1 - 7 7.3 7.6 9.7 6.8 0.5 3.4 2 1 1 4 4 4 0 HNH/Endo VII superfamily toxin with a SHH signature TPR_MLP1_2 PF07926.7 EIW78549.1 - 7.1 6.3 16.2 0.96 9.1 0.2 3.7 3 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein LRR_8 PF13855.1 EIW78551.1 - 0.14 11.9 1.3 14 5.5 0.0 3.6 3 1 0 4 4 4 0 Leucine rich repeat F-box-like PF12937.2 EIW78552.1 - 0.0021 17.7 0.1 0.0071 16.0 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIW78553.1 - 0.0037 16.9 0.2 0.0098 15.6 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIW78554.1 - 0.0093 15.6 0.3 0.048 13.4 0.2 2.3 2 0 0 2 2 2 1 F-box-like PBP1_TM PF14812.1 EIW78554.1 - 0.15 12.4 0.7 0.25 11.6 0.5 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal F-box-like PF12937.2 EIW78556.1 - 0.00081 19.0 0.1 0.0021 17.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like HTH_Mga PF08280.6 EIW78556.1 - 0.12 12.1 0.0 0.56 10.0 0.1 2.1 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain PH_9 PF15410.1 EIW78557.1 - 0.00012 22.2 0.0 0.00016 21.8 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EIW78557.1 - 0.031 14.4 0.0 0.035 14.3 0.0 1.2 1 0 0 1 1 1 0 PH domain Metallophos PF00149.23 EIW78559.1 - 2.7e-44 150.9 0.1 3.4e-44 150.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Sugar_tr PF00083.19 EIW78560.1 - 3.1e-84 283.1 23.3 3.6e-84 282.9 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW78560.1 - 4.5e-24 84.8 55.2 6e-23 81.1 21.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIW78560.1 - 0.00012 20.6 3.6 0.00012 20.6 2.5 2.8 2 1 0 2 2 2 1 MFS/sugar transport protein Gate PF07670.9 EIW78560.1 - 0.2 11.5 5.7 0.4 10.6 3.4 2.1 1 1 0 1 1 1 0 Nucleoside recognition Sugar_tr PF00083.19 EIW78561.1 - 5.3e-86 288.9 20.5 6.1e-86 288.7 14.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW78561.1 - 1.1e-27 96.6 42.3 2.1e-24 85.8 19.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG11 PF10377.4 EIW78562.1 - 2e-32 111.8 0.7 4.1e-32 110.8 0.0 1.9 2 0 0 2 2 2 1 Autophagy-related protein 11 LRR_4 PF12799.2 EIW78567.1 - 0.061 12.9 0.7 8.1 6.1 0.0 3.6 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) UPF0104 PF03706.8 EIW78568.1 - 0.0015 17.8 1.8 0.0024 17.1 1.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) Amidohydro_5 PF13594.1 EIW78569.1 - 1.3e-06 28.0 0.0 2.3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EIW78569.1 - 9.3e-05 22.2 0.0 0.00011 21.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Retinal PF15449.1 EIW78571.1 - 3.8 5.0 7.4 4.7 4.7 5.1 1.1 1 0 0 1 1 1 0 Retinal protein COesterase PF00135.23 EIW78572.1 - 9.2e-96 321.6 0.0 1.6e-95 320.8 0.0 1.4 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EIW78572.1 - 2.4e-05 23.6 0.1 4.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EIW78572.1 - 0.0015 18.1 0.1 0.012 15.2 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1769 PF08588.5 EIW78573.1 - 1e-13 51.0 0.2 2.1e-13 49.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1769) DUF1908 PF08926.6 EIW78573.1 - 0.45 9.2 5.4 0.63 8.7 3.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) DUF1248 PF06852.7 EIW78575.1 - 0.038 13.2 0.2 0.085 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1248) PEN-2 PF10251.4 EIW78575.1 - 0.35 11.1 5.7 1.3 9.3 0.1 2.7 3 0 0 3 3 3 0 Presenilin enhancer-2 subunit of gamma secretase Formyl_trans_N PF00551.14 EIW78577.1 - 2e-28 99.1 0.0 4.1e-28 98.1 0.0 1.5 1 1 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 EIW78577.1 - 1.3e-07 31.6 0.0 2.8e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain MFS_1 PF07690.11 EIW78578.1 - 1.7e-25 89.5 33.1 1.7e-25 89.5 22.9 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Stn1 PF10451.4 EIW78580.1 - 4.4e-10 38.8 0.1 0.00014 20.8 0.0 2.2 2 0 0 2 2 2 2 Telomere regulation protein Stn1 tRNA_anti-codon PF01336.20 EIW78580.1 - 0.00063 19.5 0.0 0.65 9.8 0.0 2.5 2 0 0 2 2 2 2 OB-fold nucleic acid binding domain F-box-like PF12937.2 EIW78581.1 - 0.0005 19.7 2.3 0.0012 18.5 1.6 1.7 1 0 0 1 1 1 1 F-box-like DIE2_ALG10 PF04922.7 EIW78581.1 - 0.15 11.0 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 DIE2/ALG10 family LRR_7 PF13504.1 EIW78581.1 - 3.8 8.1 7.0 45 4.8 0.0 5.6 7 0 0 7 7 7 0 Leucine rich repeat TENA_THI-4 PF03070.11 EIW78582.1 - 4.1e-13 49.5 0.2 6.9e-13 48.8 0.1 1.3 1 1 0 1 1 1 1 TENA/THI-4/PQQC family WD40 PF00400.27 EIW78583.1 - 3.6e-41 137.5 12.2 3.9e-09 36.0 0.1 10.8 11 0 0 11 11 11 7 WD domain, G-beta repeat eIF2A PF08662.6 EIW78583.1 - 0.00024 20.8 0.4 0.43 10.2 0.0 4.3 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A BBS2_Mid PF14783.1 EIW78583.1 - 0.0003 20.5 0.1 0.22 11.3 0.0 4.5 5 0 0 5 5 5 1 Ciliary BBSome complex subunit 2, middle region RCC1_2 PF13540.1 EIW78583.1 - 0.003 17.1 0.6 0.06 12.9 0.0 3.6 2 0 0 2 2 2 1 Regulator of chromosome condensation (RCC1) repeat SGL PF08450.7 EIW78583.1 - 0.0038 16.6 0.0 0.18 11.1 0.0 2.9 2 1 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Nbas_N PF15492.1 EIW78583.1 - 0.011 14.7 0.1 15 4.5 0.0 3.3 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 EIW78583.1 - 0.038 13.6 1.0 16 5.3 0.0 4.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.1 EIW78583.1 - 0.043 14.0 8.9 5.3 7.4 0.0 6.6 7 1 1 8 8 8 0 PQQ-like domain CPSF_A PF03178.10 EIW78583.1 - 0.21 10.6 0.0 3.7 6.5 0.0 2.4 2 0 0 2 2 2 0 CPSF A subunit region Mad3_BUB1_I PF08311.7 EIW78584.1 - 8.7e-22 77.2 0.1 1.3e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 ECH PF00378.15 EIW78584.1 - 0.051 12.6 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase family FDX-ACB PF03147.9 EIW78584.1 - 0.061 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Ferredoxin-fold anticodon binding domain Mcm10 PF09332.6 EIW78584.1 - 0.069 12.4 0.2 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Mcm10 replication factor Mad3_BUB1_I PF08311.7 EIW78585.1 - 4.9e-26 90.9 0.1 7.3e-26 90.4 0.1 1.2 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 ECH PF00378.15 EIW78585.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase family ABC_tran PF00005.22 EIW78586.1 - 2.5e-40 137.9 0.0 3.5e-23 82.4 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIW78586.1 - 1.4e-15 57.4 18.5 1.4e-06 27.9 2.6 5.7 4 1 0 4 4 4 3 ABC transporter transmembrane region AAA_25 PF13481.1 EIW78586.1 - 8.6e-08 31.8 0.0 0.0057 16.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EIW78586.1 - 4.6e-07 30.3 0.2 0.00042 20.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EIW78586.1 - 1.1e-06 27.7 0.0 0.033 13.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein SMC_N PF02463.14 EIW78586.1 - 1.7e-06 27.4 2.2 0.093 11.9 0.0 3.8 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIW78586.1 - 1.7e-06 28.2 1.0 0.3 11.0 0.1 4.0 2 2 0 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.13 EIW78586.1 - 1.1e-05 25.0 0.1 0.096 12.1 0.0 2.4 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_29 PF13555.1 EIW78586.1 - 1.4e-05 24.4 0.1 0.066 12.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain ResIII PF04851.10 EIW78586.1 - 1.6e-05 24.8 0.0 0.23 11.2 0.0 2.4 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_16 PF13191.1 EIW78586.1 - 2.8e-05 24.2 0.3 0.085 12.8 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain MobB PF03205.9 EIW78586.1 - 0.00012 21.8 0.2 0.16 11.6 0.0 2.4 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B Pox_A32 PF04665.7 EIW78586.1 - 0.00042 19.7 0.3 0.41 9.9 0.0 2.8 3 0 0 3 3 3 1 Poxvirus A32 protein AAA_18 PF13238.1 EIW78586.1 - 0.0022 18.2 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EIW78586.1 - 0.0023 17.4 0.0 1.2 8.4 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 EIW78586.1 - 0.0026 18.5 0.0 5.7 7.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain DEAD PF00270.24 EIW78586.1 - 0.0027 17.2 0.0 1 8.8 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase ATP_bind_1 PF03029.12 EIW78586.1 - 0.0043 16.6 0.2 2.9 7.3 0.0 2.4 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 EIW78586.1 - 0.0044 16.7 0.0 7.6 6.3 0.0 3.2 3 0 0 3 3 3 0 Part of AAA domain AAA_22 PF13401.1 EIW78586.1 - 0.0045 17.1 0.0 2.3 8.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EIW78586.1 - 0.0055 17.2 0.0 2 8.9 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 EIW78586.1 - 0.0057 15.8 0.1 1.1 8.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EIW78586.1 - 0.0067 16.1 0.0 0.28 10.8 0.0 2.2 2 0 0 2 2 2 1 Archaeal ATPase DUF87 PF01935.12 EIW78586.1 - 0.0098 15.7 0.2 1.2 8.8 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF87 NACHT PF05729.7 EIW78586.1 - 0.011 15.4 0.8 5.1 6.7 0.0 3.0 3 0 0 3 3 3 0 NACHT domain TrwB_AAD_bind PF10412.4 EIW78586.1 - 0.011 14.3 0.3 1.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Zeta_toxin PF06414.7 EIW78586.1 - 0.012 14.7 0.0 0.61 9.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.14 EIW78586.1 - 0.014 14.8 1.0 2.7 7.3 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EIW78586.1 - 0.017 15.0 0.0 4.3 7.2 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_11 PF13086.1 EIW78586.1 - 0.022 14.3 0.0 0.068 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EIW78586.1 - 0.025 13.9 0.0 7.5 5.9 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein PduV-EutP PF10662.4 EIW78586.1 - 0.033 13.6 0.4 3.9 6.9 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.24 EIW78586.1 - 0.033 14.3 0.0 0.9 9.7 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIW78586.1 - 0.033 13.8 1.3 5.3 6.7 0.0 3.5 5 0 0 5 5 2 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EIW78586.1 - 0.036 13.6 0.0 5 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EIW78586.1 - 0.089 12.3 0.1 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EIW78586.1 - 0.1 12.2 0.0 23 4.6 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 RepL PF05732.6 EIW78586.1 - 0.14 11.3 0.3 0.32 10.2 0.2 1.5 1 0 0 1 1 1 0 Firmicute plasmid replication protein (RepL) RecA PF00154.16 EIW78586.1 - 0.15 11.1 1.0 1.2 8.1 0.0 2.4 3 0 0 3 3 2 0 recA bacterial DNA recombination protein NB-ARC PF00931.17 EIW78586.1 - 0.16 10.8 0.0 1.9 7.3 0.0 2.4 3 0 0 3 3 3 0 NB-ARC domain AAA_15 PF13175.1 EIW78586.1 - 0.84 8.6 0.1 2 7.4 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain Cupin_1 PF00190.17 EIW78587.1 - 3e-30 104.5 0.0 4.2e-15 55.4 0.0 2.8 3 0 0 3 3 3 2 Cupin Cupin_2 PF07883.6 EIW78587.1 - 1.2e-25 88.7 0.5 1.6e-11 43.5 0.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EIW78587.1 - 7.4e-09 34.8 0.0 0.0028 17.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EIW78587.1 - 0.00011 21.9 0.2 0.0059 16.3 0.0 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain GPI PF06560.6 EIW78587.1 - 0.0012 17.9 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) MannoseP_isomer PF01050.13 EIW78587.1 - 0.0045 16.6 0.0 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase Cupin_4 PF08007.7 EIW78587.1 - 0.019 14.2 0.0 0.3 10.2 0.0 2.1 2 0 0 2 2 2 0 Cupin superfamily protein Cupin_8 PF13621.1 EIW78587.1 - 0.027 13.9 0.0 6.9 6.0 0.0 2.4 2 1 0 2 2 2 0 Cupin-like domain ARD PF03079.9 EIW78587.1 - 0.047 13.6 0.1 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 ARD/ARD' family RRM_1 PF00076.17 EIW78589.1 - 3e-40 135.6 0.0 1.8e-20 72.2 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW78589.1 - 4.7e-23 80.9 0.0 1.9e-12 46.9 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW78589.1 - 7e-15 54.6 0.0 7.8e-09 35.2 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EIW78589.1 - 6.1e-06 25.8 0.1 0.00082 18.9 0.0 2.9 3 0 0 3 3 3 1 Poly-adenylate binding protein, unique domain Nup35_RRM PF05172.8 EIW78589.1 - 0.013 15.2 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EIW78589.1 - 0.022 14.5 0.0 0.54 10.0 0.0 2.5 2 0 0 2 2 2 0 Limkain b1 Rad52_Rad22 PF04098.10 EIW78590.1 - 1.4e-57 193.7 0.0 1.7e-57 193.5 0.0 1.0 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein MFS_1 PF07690.11 EIW78591.1 - 1.5e-31 109.3 23.2 1.5e-31 109.3 16.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily PAT1 PF09770.4 EIW78592.1 - 0.69 8.0 22.9 0.91 7.6 15.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EIW78592.1 - 3.5 7.4 17.8 5.3 6.8 12.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.11 EIW78592.1 - 7.5 6.3 5.9 14 5.4 4.1 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Sterol_MT_C PF08498.5 EIW78593.1 - 8.7e-28 96.0 0.1 1.3e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_31 PF13847.1 EIW78593.1 - 2.1e-18 66.3 0.0 3.1e-18 65.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW78593.1 - 3.2e-18 65.9 0.0 5.7e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EIW78593.1 - 9.4e-14 51.1 0.0 1.4e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EIW78593.1 - 5.3e-13 49.0 0.1 2.2e-12 47.0 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW78593.1 - 1.9e-12 47.7 0.0 1.2e-11 45.1 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW78593.1 - 2.7e-12 47.0 0.0 6.7e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW78593.1 - 1.1e-11 45.0 0.0 1.8e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW78593.1 - 4.2e-11 42.8 0.0 7.6e-11 41.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW78593.1 - 2.6e-08 33.2 0.0 4.3e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EIW78593.1 - 1.9e-05 24.0 0.0 4.3e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_3 PF01596.12 EIW78593.1 - 5.7e-05 22.2 0.0 9.2e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase PCMT PF01135.14 EIW78593.1 - 6.2e-05 22.6 0.0 9.3e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 EIW78593.1 - 0.00013 21.5 0.0 0.00021 20.9 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_24 PF13578.1 EIW78593.1 - 0.00041 21.1 0.0 0.0032 18.2 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_2 PF00891.13 EIW78593.1 - 0.0021 17.2 0.1 0.0035 16.5 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase PrmA PF06325.8 EIW78593.1 - 0.0041 16.2 0.0 0.0064 15.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.7 EIW78593.1 - 0.0096 15.3 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW UPF0020 PF01170.13 EIW78593.1 - 0.02 14.5 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Met_10 PF02475.11 EIW78593.1 - 0.029 13.9 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Cupin_1 PF00190.17 EIW78596.1 - 3.8e-30 104.2 0.1 5.5e-16 58.3 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EIW78596.1 - 1.2e-26 92.0 1.9 2e-12 46.4 0.0 2.8 3 0 0 3 3 3 2 Cupin domain Cupin_3 PF05899.7 EIW78596.1 - 7.4e-11 41.2 0.0 0.00034 19.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EIW78596.1 - 2.4e-06 27.2 0.1 0.0087 15.7 0.0 2.8 3 0 0 3 3 3 2 AraC-like ligand binding domain Cupin_4 PF08007.7 EIW78596.1 - 6.6e-05 22.3 0.0 0.12 11.5 0.0 2.2 2 0 0 2 2 2 2 Cupin superfamily protein MannoseP_isomer PF01050.13 EIW78596.1 - 0.00025 20.7 0.0 0.032 13.8 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase ARD PF03079.9 EIW78596.1 - 0.00036 20.4 0.1 0.039 13.8 0.0 2.2 2 0 0 2 2 2 1 ARD/ARD' family Cupin_8 PF13621.1 EIW78596.1 - 0.0024 17.4 0.0 0.19 11.2 0.0 2.3 2 1 0 2 2 2 1 Cupin-like domain CENP-C_C PF11699.3 EIW78596.1 - 0.0024 17.8 0.0 0.44 10.5 0.0 2.3 2 0 0 2 2 2 1 Mif2/CENP-C like GPI PF06560.6 EIW78596.1 - 0.0032 16.5 0.0 0.0066 15.4 0.0 1.5 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) FdtA PF05523.6 EIW78596.1 - 0.033 13.6 0.0 7.1 6.1 0.0 2.2 2 0 0 2 2 2 0 WxcM-like, C-terminal 3-HAO PF06052.7 EIW78596.1 - 0.034 13.5 0.0 0.084 12.2 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyanthranilic acid dioxygenase WW PF00397.21 EIW78597.1 - 5.3e-06 26.1 1.9 0.00016 21.4 0.0 2.6 2 0 0 2 2 2 2 WW domain DUF4131 PF13567.1 EIW78597.1 - 1.3 8.4 3.8 1.8 7.9 1.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1248 PF06852.7 EIW78598.1 - 0.079 12.2 0.3 0.17 11.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1248) Formyl_trans_N PF00551.14 EIW78599.1 - 9.5e-29 100.2 0.0 1.3e-28 99.7 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 EIW78599.1 - 2.6e-06 27.4 0.0 5.2e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain F-box-like PF12937.2 EIW78600.1 - 4.2e-06 26.3 0.4 1.6e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 F-box-like DUF1193 PF06702.7 EIW78600.1 - 0.027 13.8 0.0 3.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1193) LRR_8 PF13855.1 EIW78601.1 - 0.0013 18.4 3.3 0.83 9.4 0.0 3.9 3 1 1 4 4 4 2 Leucine rich repeat LRR_4 PF12799.2 EIW78601.1 - 0.0018 17.8 5.0 0.11 12.1 0.9 4.1 3 2 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EIW78601.1 - 2.4 8.7 7.4 86 4.0 0.0 5.5 6 0 0 6 6 6 0 Leucine rich repeat Tail_P2_I PF09684.5 EIW78603.1 - 0.052 13.0 0.0 0.094 12.2 0.0 1.4 1 0 0 1 1 1 0 Phage tail protein (Tail_P2_I) DREV PF05219.7 EIW78606.1 - 0.012 14.5 0.0 0.013 14.3 0.0 1.0 1 0 0 1 1 1 0 DREV methyltransferase F-box-like PF12937.2 EIW78607.1 - 0.0017 18.0 0.1 0.012 15.2 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 EIW78608.1 - 9.4e-08 31.6 0.5 3e-07 30.0 0.4 2.0 1 0 0 1 1 1 1 F-box-like RRM_1 PF00076.17 EIW78609.1 - 5.3e-11 41.9 0.0 8e-11 41.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EIW78609.1 - 5e-09 36.4 2.9 1.1e-08 35.4 2.0 1.5 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 RRM_6 PF14259.1 EIW78609.1 - 1.9e-07 30.9 0.0 3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW78609.1 - 0.00018 21.2 0.0 0.00033 20.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) M-inducer_phosp PF06617.8 EIW78609.1 - 0.079 12.0 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 M-phase inducer phosphatase p450 PF00067.17 EIW78610.1 - 1.6e-62 211.5 0.0 6.9e-62 209.4 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 DUF998 PF06197.8 EIW78610.1 - 0.058 12.7 0.2 0.2 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF998) Ribosomal_L7Ae PF01248.21 EIW78611.1 - 1.3e-22 79.1 0.8 3.7e-22 77.6 0.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 4HBT PF03061.17 EIW78612.1 - 2.7e-08 33.8 0.0 4.4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily Sugar_tr PF00083.19 EIW78613.1 - 7.4e-78 262.1 20.3 8.3e-78 261.9 14.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW78613.1 - 1.3e-21 76.6 23.3 1.3e-21 76.6 16.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIW78613.1 - 1.5e-09 36.7 23.4 6.2e-05 21.5 4.8 3.2 2 1 1 3 3 3 3 MFS/sugar transport protein DUF791 PF05631.9 EIW78613.1 - 0.0048 15.6 1.4 0.0087 14.7 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) NodA PF02474.10 EIW78613.1 - 0.025 13.8 0.0 0.045 13.0 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein A (NodA) Sec2p PF06428.6 EIW78614.1 - 1.6e-12 47.1 8.4 1.6e-12 47.1 5.8 2.5 3 0 0 3 3 3 1 GDP/GTP exchange factor Sec2p DFP PF04127.10 EIW78615.1 - 1.5e-19 70.3 0.0 6.5e-12 45.4 0.0 2.1 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein AA_kinase PF00696.23 EIW78615.1 - 0.1 12.1 0.0 1.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Amino acid kinase family F-box-like PF12937.2 EIW78616.1 - 7.4e-08 31.9 0.4 1.6e-07 30.9 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EIW78616.1 - 0.097 12.4 0.9 0.24 11.1 0.6 1.7 1 1 0 1 1 1 0 F-box-like domain F-box-like PF12937.2 EIW78618.1 - 8.2e-09 35.0 2.0 3.5e-08 33.0 1.4 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW78618.1 - 0.68 9.6 7.2 0.69 9.6 0.2 3.6 3 0 0 3 3 3 0 F-box domain LRR_4 PF12799.2 EIW78619.1 - 0.002 17.6 4.0 11 5.7 0.0 6.1 7 0 0 7 7 7 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EIW78619.1 - 0.0093 15.9 0.0 22 5.5 0.0 4.8 5 0 0 5 5 5 1 Leucine Rich repeat F-box-like PF12937.2 EIW78620.1 - 1.8e-05 24.3 0.1 5.6e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIW78621.1 - 2.9e-06 26.9 7.8 2.9e-06 26.9 5.4 2.2 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 EIW78621.1 - 0.15 11.8 0.4 1.7 8.4 0.1 2.9 4 0 0 4 4 4 0 Leucine rich repeat LRR_7 PF13504.1 EIW78621.1 - 8.2 7.1 6.8 50 4.7 0.2 5.2 6 1 0 6 6 6 0 Leucine rich repeat F-box PF00646.28 EIW78621.1 - 9.5 6.0 10.9 3.3 7.4 0.6 3.3 2 1 0 2 2 2 0 F-box domain RRM_1 PF00076.17 EIW78622.1 - 2.6e-17 62.1 0.0 3.8e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW78622.1 - 3.5e-16 58.9 0.0 8e-07 28.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW78622.1 - 8.6e-14 51.1 0.0 6.8e-07 29.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KaiC PF06745.8 EIW78623.1 - 0.00026 20.1 0.0 0.00044 19.4 0.0 1.3 1 0 0 1 1 1 1 KaiC 5-FTHF_cyc-lig PF01812.15 EIW78624.1 - 1.3e-40 139.1 0.0 1.4e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family PIG-P PF08510.7 EIW78625.1 - 1.8e-29 101.8 0.8 2.3e-29 101.5 0.6 1.1 1 0 0 1 1 1 1 PIG-P Sulfate_transp PF00916.15 EIW78625.1 - 0.054 12.4 0.1 0.069 12.1 0.0 1.1 1 0 0 1 1 1 0 Sulfate transporter family DPM2 PF07297.7 EIW78625.1 - 1.5 9.1 7.9 3 8.1 5.5 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) zf-C2H2 PF00096.21 EIW78626.1 - 2.2e-11 43.3 3.9 8.7e-06 25.7 0.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW78626.1 - 1.4e-07 31.2 2.6 0.00053 20.1 0.1 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIW78626.1 - 0.00023 21.2 0.2 0.098 12.8 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIW78626.1 - 0.0037 17.4 0.1 0.092 12.9 0.0 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-H2C2_2 PF13465.1 EIW78626.1 - 0.0046 17.1 7.4 1.9 8.9 0.1 3.8 3 1 0 3 3 3 2 Zinc-finger double domain DUF2040 PF09745.4 EIW78626.1 - 0.11 12.3 1.0 0.54 10.0 0.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 55 (DUF2040) PRP21_like_P PF12230.3 EIW78626.1 - 0.11 11.9 0.1 0.11 11.9 0.1 2.1 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein XPG_I PF00867.13 EIW78627.1 - 9.4e-27 92.9 0.0 2e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EIW78627.1 - 1.4e-26 92.7 0.0 2.6e-26 91.8 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EIW78627.1 - 2.1e-06 27.4 0.1 4e-06 26.4 0.1 1.5 1 1 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 EIW78627.1 - 1.2e-05 25.5 0.0 2.2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.1 EIW78627.1 - 0.0026 17.8 0.0 0.026 14.6 0.0 2.4 2 1 0 2 2 2 1 Helix-hairpin-helix domain TPR_2 PF07719.12 EIW78627.1 - 0.0048 16.7 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIW78627.1 - 0.022 14.3 0.0 0.052 13.1 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Transposase_20 PF02371.11 EIW78627.1 - 0.078 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Transposase IS116/IS110/IS902 family TPR_4 PF07721.9 EIW78627.1 - 4.4 8.0 6.6 0.65 10.5 0.6 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Pox_D2 PF04701.8 EIW78629.1 - 0.06 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Pox virus D2 protein RhoGEF PF00621.15 EIW78630.1 - 0.088 12.6 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 RhoGEF domain ABC_tran PF00005.22 EIW78632.1 - 1.5e-46 158.0 0.0 1.5e-28 99.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIW78632.1 - 9.3e-37 126.9 26.6 4.1e-18 65.7 2.0 4.0 3 1 1 4 4 4 3 ABC transporter transmembrane region SMC_N PF02463.14 EIW78632.1 - 2.8e-09 36.5 0.0 0.0021 17.3 0.8 3.3 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EIW78632.1 - 2.1e-05 24.0 0.0 0.2 11.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIW78632.1 - 0.00035 20.7 0.6 1.1 9.3 0.1 3.5 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EIW78632.1 - 0.00084 18.8 0.2 0.14 11.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EIW78632.1 - 0.0013 18.2 0.1 0.34 10.3 0.0 2.8 3 0 0 3 3 3 1 AAA-like domain T2SE PF00437.15 EIW78632.1 - 0.0013 17.6 0.0 0.38 9.6 0.0 2.2 2 0 0 2 2 2 2 Type II/IV secretion system protein Vfa1 PF08432.5 EIW78632.1 - 0.0054 16.7 1.8 0.01 15.8 1.2 1.4 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 AAA_21 PF13304.1 EIW78632.1 - 0.0087 16.0 5.6 5.9 6.7 0.0 3.9 4 1 0 5 5 5 1 AAA domain FtsK_SpoIIIE PF01580.13 EIW78632.1 - 0.017 14.5 0.0 2.8 7.3 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family KaiC PF06745.8 EIW78632.1 - 0.047 12.7 0.1 4.5 6.3 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA_16 PF13191.1 EIW78632.1 - 0.052 13.5 2.0 3.3 7.6 0.0 3.3 2 1 1 3 3 3 0 AAA ATPase domain DUF87 PF01935.12 EIW78632.1 - 0.073 12.8 0.2 0.073 12.8 0.1 1.7 2 0 0 2 2 1 0 Domain of unknown function DUF87 Miro PF08477.8 EIW78632.1 - 0.7 10.3 4.0 26 5.3 0.1 3.1 3 0 0 3 3 3 0 Miro-like protein cobW PF02492.14 EIW78632.1 - 0.76 9.1 3.0 1.7 8.0 0.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Abhydrolase_6 PF12697.2 EIW78633.1 - 2.1e-25 89.9 0.5 2.5e-25 89.6 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW78633.1 - 1.5e-10 41.0 0.0 2.3e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase PF07224.6 EIW78633.1 - 0.0045 15.8 0.0 0.0085 14.9 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase PGAP1 PF07819.8 EIW78633.1 - 0.011 15.3 0.0 0.092 12.3 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein Chlorophyllase2 PF12740.2 EIW78633.1 - 0.089 11.6 0.0 0.22 10.3 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme BCLP PF12304.3 EIW78636.1 - 0.32 10.4 5.1 0.37 10.1 0.7 2.4 2 0 0 2 2 2 0 Beta-casein like protein UPF0182 PF03699.8 EIW78636.1 - 1.3 6.9 7.1 1.7 6.5 4.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF4609 PF15382.1 EIW78638.1 - 0.093 12.4 0.2 0.21 11.2 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4609) Abhydrolase_6 PF12697.2 EIW78640.1 - 1.1e-25 90.8 0.0 2.8e-25 89.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW78640.1 - 3.2e-10 39.9 0.0 3.8e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW78640.1 - 8e-05 22.2 0.0 0.0083 15.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold PGAP1 PF07819.8 EIW78640.1 - 0.00038 20.1 0.0 0.00076 19.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF900 PF05990.7 EIW78640.1 - 0.022 14.1 0.0 0.055 12.7 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Thioesterase PF00975.15 EIW78640.1 - 0.055 13.6 0.0 0.085 13.0 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Ser_hydrolase PF06821.8 EIW78640.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase F-box-like PF12937.2 EIW78641.1 - 6.3e-09 35.4 3.6 1.9e-08 33.9 2.5 1.8 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIW78641.1 - 0.0035 16.9 1.9 0.98 9.1 0.0 4.2 2 1 2 4 4 4 1 Leucine Rich repeats (2 copies) DUF1193 PF06702.7 EIW78641.1 - 0.057 12.8 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1193) LRR_7 PF13504.1 EIW78641.1 - 0.062 13.5 4.2 5.2 7.7 0.0 5.1 5 0 0 5 5 5 0 Leucine rich repeat LRR_8 PF13855.1 EIW78641.1 - 0.14 11.9 7.3 0.45 10.3 0.1 3.9 3 1 2 5 5 5 0 Leucine rich repeat F-box PF00646.28 EIW78641.1 - 0.3 10.8 5.6 6.9 6.4 0.2 3.4 3 0 0 3 3 3 0 F-box domain p450 PF00067.17 EIW78642.1 - 1.1e-53 182.3 0.0 2.7e-53 181.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW78646.1 - 8.5e-61 205.8 0.0 7.9e-38 130.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Glyco_hydro_16 PF00722.16 EIW78647.1 - 8.7e-37 126.1 3.9 1.4e-36 125.5 2.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Chitin_bind_1 PF00187.14 EIW78647.1 - 3.8 7.5 18.4 10 6.2 12.8 1.7 1 1 0 1 1 1 0 Chitin recognition protein MutS_V PF00488.16 EIW78648.1 - 1.9e-78 263.1 0.0 2.7e-78 262.5 0.0 1.2 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EIW78648.1 - 2.6e-42 144.9 0.0 4.7e-42 144.1 0.0 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EIW78648.1 - 3.1e-29 101.2 0.0 6.7e-29 100.2 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 EIW78648.1 - 3.4e-07 30.3 0.0 9.1e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.12 EIW78648.1 - 2e-06 27.9 0.2 1.3e-05 25.2 0.1 2.3 1 1 0 1 1 1 1 MutS domain II eIF-3c_N PF05470.7 EIW78648.1 - 0.39 8.7 9.3 2.9 5.8 4.8 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus DDE_1 PF03184.14 EIW78650.1 - 6.2e-05 22.2 0.0 7.3e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIW78650.1 - 0.00055 19.7 0.0 0.00083 19.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3437 PF11919.3 EIW78652.1 - 0.026 14.2 0.1 14 5.4 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) DsrD PF08679.6 EIW78652.1 - 0.26 11.2 0.0 0.6 10.1 0.0 1.5 1 0 0 1 1 1 0 Dissimilatory sulfite reductase D (DsrD) p450 PF00067.17 EIW78654.1 - 2.3e-42 145.0 0.0 3.3e-40 138.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 SIS PF01380.17 EIW78655.1 - 4.5e-62 207.4 0.1 7.7e-34 116.1 0.0 2.5 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EIW78655.1 - 3.8e-25 88.3 0.5 2.2e-18 66.1 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EIW78655.1 - 1.7e-20 73.3 0.0 3.6e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EIW78655.1 - 3.7e-13 49.3 0.0 8e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EIW78655.1 - 3e-08 32.6 0.0 4.4e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.1 EIW78655.1 - 0.0026 17.4 0.0 0.026 14.2 0.0 2.5 2 1 0 2 2 2 1 SIS domain Abhydrolase_6 PF12697.2 EIW78656.1 - 3e-28 99.2 2.1 7.9e-28 97.8 1.5 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW78656.1 - 4.6e-12 46.0 0.0 1.5e-10 41.0 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW78656.1 - 8.9e-11 41.7 0.0 1.2e-09 38.1 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIW78656.1 - 0.00012 21.8 0.0 0.00043 20.0 0.0 2.0 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 EIW78656.1 - 0.0012 17.8 0.0 0.0016 17.3 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EIW78656.1 - 0.0049 15.7 0.0 0.0075 15.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Esterase PF00756.15 EIW78656.1 - 0.0083 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase DLH PF01738.13 EIW78656.1 - 0.028 13.7 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family p450 PF00067.17 EIW78658.1 - 2.1e-76 257.3 0.0 4.7e-76 256.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 CsbD PF05532.7 EIW78659.1 - 0.051 13.2 0.8 0.12 12.0 0.6 1.6 1 0 0 1 1 1 0 CsbD-like TPR_10 PF13374.1 EIW78659.1 - 0.43 10.5 4.7 0.12 12.3 1.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat ABC_tran PF00005.22 EIW78660.1 - 1.7e-38 132.0 0.0 7.2e-23 81.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIW78660.1 - 9.6e-21 74.4 4.9 2e-11 43.8 0.6 4.4 3 2 1 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 EIW78660.1 - 3.8e-06 26.3 0.0 0.14 11.3 0.0 2.9 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EIW78660.1 - 0.00033 20.1 0.0 0.075 12.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EIW78660.1 - 0.018 15.0 0.1 4 7.3 0.0 2.8 3 1 0 3 3 3 0 AAA domain AAA_10 PF12846.2 EIW78660.1 - 0.022 14.2 0.0 4.8 6.5 0.0 2.7 3 0 0 3 3 3 0 AAA-like domain AAA_29 PF13555.1 EIW78660.1 - 0.029 13.9 0.4 3.1 7.3 0.1 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain T2SE PF00437.15 EIW78660.1 - 0.06 12.2 0.0 8.9 5.1 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.1 EIW78660.1 - 0.13 12.4 0.1 7.8 6.6 0.0 3.0 2 1 0 2 2 2 0 AAA domain p450 PF00067.17 EIW78661.1 - 5.3e-74 249.4 0.0 6.7e-74 249.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DcpS_C PF11969.3 EIW78662.1 - 0.034 14.3 0.1 0.062 13.5 0.0 1.4 1 0 0 1 1 1 0 Scavenger mRNA decapping enzyme C-term binding Sulfotransfer_3 PF13469.1 EIW78662.1 - 0.18 12.6 6.3 0.55 11.1 2.9 2.7 2 1 0 2 2 2 0 Sulfotransferase family ADIP PF11559.3 EIW78664.1 - 5.5e-10 39.3 16.2 5.5e-10 39.3 11.3 3.3 3 1 1 4 4 4 1 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 EIW78664.1 - 0.88 7.3 12.2 0.24 9.1 2.4 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Gly-zipper_OmpA PF13436.1 EIW78664.1 - 1.3 8.7 14.0 5.8 6.6 0.0 3.2 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain DUF342 PF03961.8 EIW78664.1 - 1.5 7.1 8.9 0.64 8.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Mcp5_PH PF12814.2 EIW78667.1 - 1.3e-43 147.7 0.0 3.5e-43 146.4 0.0 1.8 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology AAA_13 PF13166.1 EIW78667.1 - 0.00089 17.8 2.5 0.00089 17.8 1.7 1.8 2 0 0 2 2 2 1 AAA domain Spc7 PF08317.6 EIW78667.1 - 0.11 11.1 12.0 0.03 13.0 5.3 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.7 EIW78667.1 - 0.12 12.1 18.8 2.1 8.0 0.0 3.6 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein PH PF00169.24 EIW78667.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 PH domain DUF972 PF06156.8 EIW78667.1 - 0.19 12.1 7.0 0.45 10.8 3.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) ATG16 PF08614.6 EIW78667.1 - 0.27 11.0 21.1 0.18 11.5 4.4 3.4 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) DUF4407 PF14362.1 EIW78667.1 - 0.61 8.9 17.6 7.7 5.3 10.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Reo_sigmaC PF04582.7 EIW78667.1 - 0.95 8.5 4.7 14 4.7 0.1 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein APG6 PF04111.7 EIW78667.1 - 2.7 6.9 13.6 0.49 9.4 5.9 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 p450 PF00067.17 EIW78668.1 - 1.1e-06 27.5 0.0 3.4e-06 25.8 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EIW78672.1 - 1e-33 116.5 57.0 1e-33 116.5 39.5 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIW78672.1 - 1.2e-19 69.9 20.8 1.6e-19 69.5 14.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIW78672.1 - 2.9e-13 49.2 15.5 2.9e-13 49.2 10.7 3.2 4 1 1 5 5 5 1 Sugar (and other) transporter DUF2748 PF10871.3 EIW78676.1 - 0.1 11.0 0.1 0.13 10.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2748) Melibiase PF02065.13 EIW78677.1 - 2.1e-11 43.1 0.3 3e-06 26.1 0.0 3.0 3 0 0 3 3 3 3 Melibiase Calici_coat PF00915.15 EIW78677.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Calicivirus coat protein IncA PF04156.9 EIW78678.1 - 5.7e-05 22.7 15.7 5.7e-05 22.7 10.9 7.9 3 2 4 7 7 7 3 IncA protein GAS PF13851.1 EIW78678.1 - 0.00026 20.2 4.2 0.00026 20.2 2.9 8.2 3 2 5 9 9 9 5 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 EIW78678.1 - 2.1 7.4 54.3 0.77 8.8 2.5 6.4 2 2 4 6 6 6 0 Reovirus sigma C capsid protein Sec23_trunk PF04811.10 EIW78679.1 - 2.9e-36 125.0 0.0 4e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EIW78679.1 - 1.5e-16 59.6 0.0 2.4e-16 59.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EIW78679.1 - 7.2e-14 51.0 0.8 1.7e-13 49.9 0.5 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EIW78679.1 - 1.6e-09 38.1 0.0 3e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.17 EIW78679.1 - 0.00077 19.1 0.0 0.0021 17.6 0.0 1.7 2 0 0 2 2 2 1 Gelsolin repeat DUF4140 PF13600.1 EIW78682.1 - 0.1 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Pkinase PF00069.20 EIW78683.1 - 2e-05 23.9 0.0 3.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EIW78683.1 - 0.0027 17.4 3.1 0.62 9.7 0.1 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Sucrose_synth PF00862.14 EIW78683.1 - 0.11 10.4 0.0 0.14 10.1 0.0 1.1 1 0 0 1 1 1 0 Sucrose synthase Choline_kinase PF01633.15 EIW78683.1 - 0.16 11.5 0.0 1.7 8.1 0.0 2.0 1 1 1 2 2 2 0 Choline/ethanolamine kinase DUF3733 PF12534.3 EIW78684.1 - 0.86 8.9 7.4 0.14 11.4 0.8 2.6 2 1 0 2 2 2 0 Leucine-rich repeat containing protein 8 DctQ PF04290.7 EIW78684.1 - 1.2 8.8 14.1 1.2 8.8 7.8 2.5 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF1129 PF06570.6 EIW78684.1 - 5.1 6.3 11.8 1.4 8.1 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) PepSY_TM_2 PF13703.1 EIW78684.1 - 6 7.1 8.0 9.7 6.4 2.7 2.8 2 1 0 2 2 2 0 PepSY-associated TM helix Aldo_ket_red PF00248.16 EIW78687.1 - 1e-59 201.7 0.1 1.2e-59 201.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family MR_MLE_C PF13378.1 EIW78688.1 - 1e-15 57.6 0.1 2.5e-15 56.3 0.1 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EIW78688.1 - 1.7e-14 54.0 0.1 4.8e-14 52.6 0.0 1.8 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EIW78688.1 - 4e-09 36.4 0.0 9.1e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Ribosomal_L33 PF00471.15 EIW78689.1 - 4.6e-09 36.3 0.0 6.2e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 Pex24p PF06398.6 EIW78691.1 - 1.1 8.0 4.3 4.3 6.0 3.0 1.8 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin UBN2_2 PF14227.1 EIW78692.1 - 0.00027 20.4 0.0 0.00048 19.6 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Suf PF05843.9 EIW78692.1 - 0.0052 16.5 4.3 0.006 16.3 3.0 1.2 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) UBN2 PF14223.1 EIW78692.1 - 0.03 14.0 0.0 0.051 13.3 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EIW78692.1 - 0.063 12.8 0.1 0.063 12.8 0.0 2.7 2 1 0 2 2 2 0 gag-polypeptide of LTR copia-type DUF4219 PF13961.1 EIW78692.1 - 0.088 12.2 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) TFIIA PF03153.8 EIW78692.1 - 0.76 9.6 15.0 0.94 9.2 10.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.4 EIW78692.1 - 0.99 9.6 8.9 1.7 8.9 6.1 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like Tim54 PF11711.3 EIW78692.1 - 1.1 7.7 7.9 10 4.5 5.7 1.9 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF2413 PF10310.4 EIW78692.1 - 3.1 6.5 15.8 4.5 5.9 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Pol_alpha_B_N PF08418.5 EIW78692.1 - 3.4 7.1 16.3 5.2 6.5 11.3 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Abhydrolase_6 PF12697.2 EIW78693.1 - 1.7e-24 86.9 0.0 2e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW78693.1 - 1.6e-11 44.1 0.0 2.1e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EIW78693.1 - 6.9e-05 22.5 0.0 0.00015 21.4 0.0 1.5 2 0 0 2 2 2 1 PGAP1-like protein Lipase_2 PF01674.13 EIW78693.1 - 0.0021 17.4 0.0 0.0032 16.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 2) DUF900 PF05990.7 EIW78693.1 - 0.035 13.4 0.0 0.063 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF4010 PF13194.1 EIW78693.1 - 0.039 13.2 0.0 0.056 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4010) Chlorophyllase PF07224.6 EIW78693.1 - 0.09 11.5 0.0 0.18 10.5 0.0 1.4 2 0 0 2 2 2 0 Chlorophyllase Ser_hydrolase PF06821.8 EIW78693.1 - 0.095 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase DUF676 PF05057.9 EIW78693.1 - 0.12 11.6 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) MR_MLE_C PF13378.1 EIW78694.1 - 1.1e-16 60.7 0.1 3e-16 59.3 0.0 1.8 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EIW78694.1 - 4.6e-13 49.4 0.2 1.5e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EIW78694.1 - 9.1e-10 38.5 0.0 2.3e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain BTB PF00651.26 EIW78695.1 - 3.6e-07 30.1 0.0 6e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Melibiase PF02065.13 EIW78697.1 - 3.6e-12 45.7 0.2 3.4e-08 32.5 0.0 3.0 3 0 0 3 3 3 3 Melibiase Melibiase PF02065.13 EIW78698.1 - 5.2e-17 61.6 0.0 3.2e-14 52.4 0.0 2.7 3 0 0 3 3 3 2 Melibiase Melibiase PF02065.13 EIW78699.1 - 3.7e-06 25.8 0.0 5e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Melibiase Glucos_trans_II PF14264.1 EIW78700.1 - 0.0048 15.9 4.9 0.015 14.3 3.4 1.8 1 1 0 1 1 1 1 Glucosyl transferase GtrII G3P_acyltransf PF02660.10 EIW78700.1 - 0.011 15.2 1.7 0.77 9.2 0.0 2.3 2 0 0 2 2 2 0 Glycerol-3-phosphate acyltransferase DUF3955 PF13127.1 EIW78700.1 - 0.038 13.5 0.2 0.13 11.8 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3955) DUF1304 PF06993.7 EIW78700.1 - 0.12 12.0 3.4 0.11 12.2 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1304) Wzy_C PF04932.10 EIW78700.1 - 0.36 10.5 4.4 1.1 9.0 3.0 1.7 1 1 0 1 1 1 0 O-Antigen ligase Peptidase_C13 PF01650.13 EIW78701.1 - 1.4e-47 162.2 0.0 1.8e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family HCNGP PF07818.8 EIW78702.1 - 4.3e-22 77.9 0.0 6.4e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 HCNGP-like protein MFS_1 PF07690.11 EIW78704.1 - 1.3e-32 112.8 33.9 1.3e-32 112.8 23.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.2 EIW78705.1 - 2.1e-07 30.5 0.6 2.3e-05 24.0 0.0 3.7 4 1 0 4 4 4 1 F-box-like DUF310 PF03750.8 EIW78705.1 - 0.15 12.2 0.1 0.29 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF310) BTB PF00651.26 EIW78706.1 - 0.017 15.1 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 BTB/POZ domain Beta-lactamase PF00144.19 EIW78707.1 - 4.2e-42 144.3 0.0 6.5e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EIW78707.1 - 0.0016 18.2 0.0 0.05 13.4 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3471) WD40 PF00400.27 EIW78709.1 - 6.6e-37 124.0 21.5 2.8e-10 39.6 0.1 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat Kelch_6 PF13964.1 EIW78709.1 - 0.0021 18.1 0.3 4.4 7.6 0.0 4.3 4 0 0 4 4 4 1 Kelch motif Nup160 PF11715.3 EIW78709.1 - 0.0069 14.5 1.0 1.3 7.1 0.0 2.7 2 1 1 3 3 3 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 EIW78709.1 - 0.093 11.8 0.1 18 4.3 0.0 3.0 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal MIF PF01187.13 EIW78709.1 - 0.11 12.5 0.0 1 9.4 0.0 2.1 2 0 0 2 2 2 0 Macrophage migration inhibitory factor (MIF) FG-GAP_2 PF14312.1 EIW78709.1 - 1 9.4 4.7 7.7 6.6 0.5 3.5 3 0 0 3 3 3 0 FG-GAP repeat PQQ_3 PF13570.1 EIW78709.1 - 3.5 8.0 9.9 31 5.0 0.0 5.1 3 2 2 5 5 5 0 PQQ-like domain WD40 PF00400.27 EIW78710.1 - 4.7e-67 219.6 18.7 1.3e-09 37.5 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EIW78710.1 - 2e-23 82.3 7.3 3.5e-23 81.5 5.1 1.4 1 0 0 1 1 1 1 Tup N-terminal Spc7 PF08317.6 EIW78710.1 - 0.00012 20.8 0.4 0.00018 20.2 0.3 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Nucleoporin_N PF08801.6 EIW78710.1 - 0.0003 19.6 0.2 1.3 7.6 0.0 3.1 1 1 2 3 3 3 1 Nup133 N terminal like Nbas_N PF15492.1 EIW78710.1 - 0.00095 18.3 0.4 8.9 5.3 0.0 3.7 3 1 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Mnd1 PF03962.10 EIW78710.1 - 0.0023 17.6 1.7 0.0023 17.6 1.2 2.2 2 0 0 2 2 1 1 Mnd1 family eIF2A PF08662.6 EIW78710.1 - 0.0026 17.5 0.0 3.1 7.4 0.0 3.4 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF3450 PF11932.3 EIW78710.1 - 0.013 14.7 1.2 0.022 14.0 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Cytochrom_D1 PF02239.11 EIW78710.1 - 0.017 13.4 0.9 0.25 9.6 0.0 2.5 2 1 1 3 3 3 0 Cytochrome D1 heme domain PD40 PF07676.7 EIW78710.1 - 0.024 14.3 0.1 1.3e+02 2.4 0.0 5.1 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EIW78710.1 - 0.028 12.5 0.2 0.47 8.5 0.0 2.7 1 1 2 3 3 3 0 Nucleoporin Nup120/160 Bacillus_HBL PF05791.6 EIW78710.1 - 0.052 12.9 1.0 0.094 12.0 0.7 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) LXG PF04740.7 EIW78710.1 - 0.38 10.5 4.2 0.62 9.8 2.9 1.2 1 0 0 1 1 1 0 LXG domain of WXG superfamily DUF4246 PF14033.1 EIW78710.1 - 3 6.3 7.6 6.2 5.3 5.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4246) MIP-T3 PF10243.4 EIW78710.1 - 5.6 5.3 28.5 1.4 7.2 16.6 1.8 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 WD40 PF00400.27 EIW78711.1 - 0.1 12.5 0.2 1.6 8.7 0.0 2.1 2 0 0 2 2 2 0 WD domain, G-beta repeat DUF1793 PF08760.6 EIW78712.1 - 2.3e-42 144.7 0.5 5.3e-42 143.5 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Metallophos_2 PF12850.2 EIW78713.1 - 3.5e-18 65.9 0.1 4e-17 62.4 0.1 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EIW78713.1 - 5.1e-05 22.7 1.3 0.046 13.1 0.5 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase DUF917 PF06032.7 EIW78714.1 - 1.4e-104 349.4 0.0 2.2e-104 348.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EIW78714.1 - 4.9e-51 173.5 4.2 3.2e-49 167.5 1.2 2.8 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EIW78714.1 - 1.4e-30 106.1 0.8 6.3e-28 97.4 0.0 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EIW78714.1 - 4.8e-08 31.7 0.5 0.00065 18.1 0.0 2.4 2 0 0 2 2 2 2 MutL protein StbA PF06406.6 EIW78714.1 - 0.0022 16.9 0.6 0.13 11.1 0.1 2.4 2 0 0 2 2 2 1 StbA protein BcrAD_BadFG PF01869.15 EIW78714.1 - 0.0047 16.2 3.7 0.014 14.6 0.1 2.5 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family FAD_binding_4 PF01565.18 EIW78714.1 - 0.017 14.5 0.3 0.48 9.8 0.0 3.3 4 0 0 4 4 4 0 FAD binding domain MreB_Mbl PF06723.8 EIW78714.1 - 0.093 11.3 3.7 0.13 10.8 0.0 2.7 3 0 0 3 3 3 0 MreB/Mbl protein UPF0203 PF05254.7 EIW78715.1 - 5.6e-19 67.7 0.8 2.2e-17 62.6 0.5 2.1 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) UCR_hinge PF02320.11 EIW78715.1 - 0.076 12.9 1.0 4.5 7.2 0.1 2.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein HET PF06985.6 EIW78716.1 - 7.3e-14 52.1 1.3 4.7e-10 39.7 0.0 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_trans_2_3 PF13632.1 EIW78716.1 - 0.065 12.9 0.1 0.085 12.5 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase family group 2 MAGSP PF03082.9 EIW78719.1 - 0.0061 15.9 0.3 0.011 15.1 0.2 1.4 1 0 0 1 1 1 1 Male accessory gland secretory protein DivIC PF04977.10 EIW78719.1 - 0.04 13.4 0.8 0.04 13.4 0.5 2.7 2 0 0 2 2 2 0 Septum formation initiator V_ATPase_I PF01496.14 EIW78719.1 - 0.3 8.8 1.3 0.41 8.4 0.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mod_r PF07200.8 EIW78719.1 - 0.37 10.6 12.4 0.09 12.6 1.9 3.1 2 1 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Lge1 PF11488.3 EIW78719.1 - 0.58 10.3 5.4 1 9.5 0.1 3.1 3 1 0 3 3 3 0 Transcriptional regulatory protein LGE1 TPR_MLP1_2 PF07926.7 EIW78719.1 - 1.3 8.7 10.5 2.4 7.8 0.5 3.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF972 PF06156.8 EIW78719.1 - 9.7 6.5 8.3 5.8 7.3 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF972) Med14 PF08638.6 EIW78720.1 - 4.4e-49 166.3 0.1 9.1e-49 165.3 0.1 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 LSM PF01423.17 EIW78721.1 - 1.9e-18 65.7 1.3 2.4e-18 65.4 0.9 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EIW78721.1 - 0.026 14.4 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Gemin7 PF11095.3 EIW78721.1 - 0.083 12.6 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) DUF2763 PF10961.3 EIW78721.1 - 3 8.2 8.5 2.8 8.4 5.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2763) DUF4218 PF13960.1 EIW78723.1 - 0.043 13.2 0.1 0.045 13.1 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4218) Sporozoite_P67 PF05642.6 EIW78723.1 - 0.11 10.3 0.0 0.12 10.1 0.0 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CLTH PF10607.4 EIW78725.1 - 0.072 12.7 0.0 0.077 12.6 0.0 1.0 1 0 0 1 1 1 0 CTLH/CRA C-terminal to LisH motif domain PCI PF01399.22 EIW78728.1 - 1.2e-06 28.7 2.0 1.6e-06 28.3 0.9 1.6 2 0 0 2 2 2 1 PCI domain DUF735 PF05246.6 EIW78730.1 - 0.083 12.6 0.1 0.096 12.4 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF735) Vps52 PF04129.7 EIW78730.1 - 0.092 11.2 0.0 0.092 11.2 0.0 1.0 1 0 0 1 1 1 0 Vps52 / Sac2 family DDE_1 PF03184.14 EIW78734.1 - 1.7e-05 24.0 0.1 1.9e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIW78734.1 - 0.0022 17.7 0.0 0.0044 16.7 0.0 1.4 2 0 0 2 2 2 1 DDE superfamily endonuclease DUF659 PF04937.10 EIW78735.1 - 5.3e-07 29.2 0.2 7.4e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Aminotran_4 PF01063.14 EIW78735.1 - 0.0001 21.8 0.1 0.00016 21.2 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class IV DUF1088 PF06469.6 EIW78735.1 - 0.0084 15.5 0.2 0.4 10.0 0.0 2.4 2 1 1 3 3 3 1 Domain of Unknown Function (DUF1088) XH PF03469.9 EIW78735.1 - 0.018 14.6 0.3 1.3 8.6 0.4 2.1 1 1 1 2 2 2 0 XH domain RimK PF08443.6 EIW78735.1 - 0.084 12.3 0.3 0.15 11.4 0.0 1.5 2 0 0 2 2 2 0 RimK-like ATP-grasp domain EIAV_Rev PF11129.3 EIW78735.1 - 0.14 12.1 0.0 0.45 10.5 0.0 2.0 1 1 1 2 2 2 0 Rev protein of equine infectious anaemia virus Transposase_21 PF02992.9 EIW78736.1 - 1.4e-11 43.9 0.0 2.4e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EIW78736.1 - 0.0045 16.4 0.1 0.0089 15.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Gag_spuma PF03276.9 EIW78738.1 - 0.46 8.7 5.2 0.64 8.2 3.6 1.1 1 0 0 1 1 1 0 Spumavirus gag protein zf-C2H2 PF00096.21 EIW78739.1 - 8.9e-22 76.0 83.3 0.0036 17.5 1.9 10.4 10 0 0 10 10 10 10 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW78739.1 - 3.7e-13 48.7 80.1 0.0095 16.2 1.0 10.3 10 0 0 10 10 10 8 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIW78739.1 - 1.9e-09 37.3 84.2 7.2e-06 26.0 2.0 12.1 12 1 1 13 13 13 5 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EIW78739.1 - 4.2e-07 29.9 30.6 0.095 12.8 0.5 8.4 8 0 0 8 8 8 4 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EIW78739.1 - 0.00016 21.4 23.7 0.018 14.9 0.1 6.8 6 0 0 6 6 6 2 C2H2-type zinc finger zf-met PF12874.2 EIW78739.1 - 0.051 13.8 2.0 0.051 13.8 1.4 8.0 9 0 0 9 9 9 0 Zinc-finger of C2H2 type Mut7-C PF01927.11 EIW78739.1 - 0.25 11.3 5.5 3 7.8 1.7 3.2 3 1 0 3 3 3 0 Mut7-C RNAse domain BTB PF00651.26 EIW78740.1 - 1.4e-10 41.1 0.0 3.6e-10 39.8 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain CAP_GLY PF01302.20 EIW78740.1 - 6.3e-09 35.4 2.1 7.5e-08 31.9 1.2 2.3 2 0 0 2 2 2 1 CAP-Gly domain DIOX_N PF14226.1 EIW78741.1 - 1.1e-14 54.9 0.0 1.8e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIW78741.1 - 2.9e-14 53.1 0.0 4.8e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sel1 PF08238.7 EIW78742.1 - 2.5e-10 40.6 19.5 0.00052 20.5 0.5 6.9 7 0 0 7 7 7 3 Sel1 repeat TPR_11 PF13414.1 EIW78742.1 - 0.0014 18.1 0.2 0.0014 18.1 0.1 2.6 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 EIW78742.1 - 0.01 15.7 0.0 0.01 15.7 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIW78742.1 - 0.01 16.3 3.6 0.33 11.6 0.0 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIW78742.1 - 0.017 14.6 4.8 0.018 14.6 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribosomal_L16 PF00252.13 EIW78743.1 - 2.2e-33 114.8 0.0 2.6e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e RTBV_P46 PF06216.6 EIW78743.1 - 0.08 11.7 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein PAS_9 PF13426.1 EIW78744.1 - 9.1e-31 106.3 0.0 9.9e-17 61.2 0.0 3.4 3 0 0 3 3 3 3 PAS domain PAS PF00989.19 EIW78744.1 - 6.1e-13 48.5 0.0 1.1e-05 25.2 0.0 3.8 3 1 0 3 3 3 3 PAS fold PAS_3 PF08447.6 EIW78744.1 - 5.8e-09 35.9 0.1 5.5e-05 23.1 0.0 4.1 3 2 0 3 3 3 2 PAS fold PAS_4 PF08448.5 EIW78744.1 - 4.2e-07 29.9 0.0 0.017 15.1 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.1 EIW78744.1 - 9.4e-06 25.5 0.0 5.5e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_8 PF13188.1 EIW78744.1 - 0.0072 16.1 0.0 2.2 8.2 0.0 2.8 3 0 0 3 3 3 1 PAS domain HALZ PF02183.13 EIW78744.1 - 0.071 12.8 0.3 0.14 11.8 0.2 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper BCDHK_Adom3 PF10436.4 EIW78745.1 - 1.3e-66 223.1 0.0 1.8e-66 222.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EIW78745.1 - 1.8e-19 69.4 0.0 3.9e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EIW78745.1 - 0.0016 18.1 0.0 0.0027 17.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CBM_20 PF00686.14 EIW78746.1 - 5.3e-31 106.0 0.1 1.6e-30 104.5 0.1 1.9 1 0 0 1 1 1 1 Starch binding domain Alpha-amylase PF00128.19 EIW78746.1 - 5.7e-19 68.6 0.1 1e-18 67.8 0.1 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EIW78746.1 - 1.8e-10 40.8 0.0 4.5e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.13 EIW78746.1 - 0.003 17.5 0.2 0.48 10.4 0.0 2.5 2 0 0 2 2 2 2 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF367 PF04034.8 EIW78747.1 - 2.3e-42 143.5 0.0 6.6e-40 135.6 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF367) RLI PF04068.10 EIW78747.1 - 7.6e-14 51.0 0.1 1.2e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI EIF_2_alpha PF07541.7 EIW78748.1 - 3e-36 123.5 0.0 7.2e-36 122.3 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EIW78748.1 - 7.5e-13 48.3 0.7 1.5e-12 47.4 0.5 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Kinesin PF00225.18 EIW78749.1 - 2.1e-91 306.1 0.0 2.1e-91 306.1 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain TPR_12 PF13424.1 EIW78749.1 - 0.0049 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIW78749.1 - 0.012 15.5 0.0 0.031 14.1 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 EIW78749.1 - 0.032 14.0 2.6 0.044 13.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Baculo_E66 PF04850.7 EIW78749.1 - 0.083 11.8 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Baculovirus E66 occlusion-derived virus envelope protein TPR_14 PF13428.1 EIW78749.1 - 0.12 13.0 0.9 0.26 12.0 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-CCCH PF00642.19 EIW78750.1 - 2.4e-05 23.8 6.7 0.00027 20.5 0.7 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EIW78750.1 - 2.2 8.4 11.7 0.48 10.5 1.6 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Pkinase PF00069.20 EIW78751.1 - 9.3e-76 254.3 0.0 1.1e-75 254.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW78751.1 - 5.6e-32 110.8 0.0 1.4e-31 109.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW78751.1 - 3.5e-05 22.9 0.0 5.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIW78751.1 - 9.4e-05 21.5 0.1 0.00014 20.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW78751.1 - 0.0011 18.6 0.6 0.72 9.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family YukC PF10140.4 EIW78751.1 - 0.055 12.0 0.0 0.068 11.7 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC PB1 PF00564.19 EIW78752.1 - 1.2e-10 40.8 0.0 2.2e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 PB1 domain TPR_11 PF13414.1 EIW78752.1 - 1.5e-07 30.9 8.0 4.1e-07 29.5 0.9 3.1 2 1 1 3 3 3 1 TPR repeat TPR_2 PF07719.12 EIW78752.1 - 8.1e-06 25.3 8.4 0.0025 17.5 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIW78752.1 - 2.1e-05 23.8 6.1 0.00036 20.0 0.1 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIW78752.1 - 0.001 18.6 1.4 0.014 15.1 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIW78752.1 - 0.0011 19.5 3.3 0.0011 19.5 2.3 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIW78752.1 - 0.012 15.3 0.1 0.059 13.1 0.0 2.1 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EIW78752.1 - 0.022 14.6 4.8 0.037 13.9 0.9 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EIW78752.1 - 0.03 14.5 0.5 1.2 9.5 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIW78752.1 - 5.2 7.9 11.5 0.41 11.4 0.4 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat p450 PF00067.17 EIW78754.1 - 1.9e-63 214.6 0.0 2.2e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NEMO PF11577.3 EIW78754.1 - 0.096 12.4 0.7 0.18 11.5 0.5 1.4 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO Peptidase_M3 PF01432.15 EIW78755.1 - 6.2e-29 101.3 0.0 7.5e-29 101.0 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 AAA_2 PF07724.9 EIW78756.1 - 8.9e-49 165.6 0.0 2.5e-45 154.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EIW78756.1 - 3.7e-21 74.8 2.7 5.3e-21 74.3 0.1 2.6 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EIW78756.1 - 3.1e-20 72.7 0.1 3.3e-11 43.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIW78756.1 - 1.3e-17 63.7 0.0 5.8e-11 42.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIW78756.1 - 2.9e-12 46.9 5.7 8e-05 22.6 0.0 4.4 3 2 1 4 4 3 2 AAA ATPase domain AAA_22 PF13401.1 EIW78756.1 - 1.3e-09 38.2 0.5 0.0015 18.7 0.0 4.0 3 2 1 4 4 4 2 AAA domain IstB_IS21 PF01695.12 EIW78756.1 - 7.4e-09 35.2 0.2 0.037 13.4 0.0 3.9 3 1 1 4 4 4 2 IstB-like ATP binding protein Sigma54_activat PF00158.21 EIW78756.1 - 1.7e-07 30.8 0.0 7.1e-06 25.5 0.0 2.4 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_23 PF13476.1 EIW78756.1 - 6.3e-07 29.9 3.7 0.083 13.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_14 PF13173.1 EIW78756.1 - 6.4e-07 29.3 0.0 0.0034 17.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EIW78756.1 - 8.8e-07 29.2 0.1 0.028 14.7 0.0 3.2 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EIW78756.1 - 1.2e-06 29.2 5.5 0.05 14.4 0.0 4.0 3 1 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 EIW78756.1 - 1.7e-06 27.3 0.2 0.13 11.4 0.0 3.2 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EIW78756.1 - 1.9e-05 24.6 1.6 0.22 11.4 0.0 4.1 4 1 0 4 4 3 1 AAA domain ABC_tran PF00005.22 EIW78756.1 - 4.3e-05 23.8 2.8 0.021 15.1 0.0 3.3 3 0 0 3 3 3 1 ABC transporter RuvB_N PF05496.7 EIW78756.1 - 5.7e-05 22.2 0.5 0.32 9.9 0.2 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EIW78756.1 - 7.6e-05 22.3 0.0 0.029 14.1 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 EIW78756.1 - 0.00014 21.3 0.0 0.59 9.4 0.0 3.7 3 1 0 3 3 2 1 AAA domain DUF258 PF03193.11 EIW78756.1 - 0.0006 19.0 0.0 0.88 8.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EIW78756.1 - 0.00093 19.3 0.0 2 8.6 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.7 EIW78756.1 - 0.00094 18.3 1.0 0.064 12.3 0.0 3.1 3 1 1 4 4 4 1 Zeta toxin Arch_ATPase PF01637.13 EIW78756.1 - 0.00097 18.8 10.1 0.0097 15.6 0.2 4.4 3 2 1 4 4 3 1 Archaeal ATPase AAA_24 PF13479.1 EIW78756.1 - 0.00098 18.7 0.0 0.69 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EIW78756.1 - 0.0039 16.9 0.0 1.9 8.1 0.0 2.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EIW78756.1 - 0.0044 16.5 0.0 3 7.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SE PF00437.15 EIW78756.1 - 0.0047 15.8 0.0 0.15 10.9 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein NACHT PF05729.7 EIW78756.1 - 0.0049 16.5 0.0 0.52 9.9 0.0 2.7 2 0 0 2 2 2 1 NACHT domain DNA_pol3_delta2 PF13177.1 EIW78756.1 - 0.0051 16.4 0.0 0.088 12.4 0.0 2.7 3 1 0 3 3 2 1 DNA polymerase III, delta subunit NTPase_1 PF03266.10 EIW78756.1 - 0.015 15.0 0.0 3.8 7.1 0.0 3.6 3 0 0 3 3 3 0 NTPase Miro PF08477.8 EIW78756.1 - 0.016 15.7 0.4 1 9.8 0.0 3.3 3 0 0 3 3 3 0 Miro-like protein AAA_21 PF13304.1 EIW78756.1 - 0.018 15.0 0.4 4.8 7.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 EIW78756.1 - 0.018 15.0 0.1 3.6 7.5 0.0 2.8 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_33 PF13671.1 EIW78756.1 - 0.024 14.5 0.3 6.3 6.6 0.0 3.1 3 0 0 3 3 2 0 AAA domain Bac_DnaA PF00308.13 EIW78756.1 - 0.035 13.7 0.7 12 5.5 0.0 2.9 3 0 0 3 3 3 0 Bacterial dnaA protein AAA_3 PF07726.6 EIW78756.1 - 0.04 13.5 0.1 12 5.5 0.0 3.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 EIW78756.1 - 0.074 12.4 0.0 7.1 6.0 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ResIII PF04851.10 EIW78756.1 - 0.081 12.7 0.0 19 5.0 0.0 2.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Torsin PF06309.6 EIW78756.1 - 0.1 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Torsin PduV-EutP PF10662.4 EIW78756.1 - 0.11 11.9 0.0 1.8 8.0 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF3584 PF12128.3 EIW78756.1 - 0.15 9.3 9.4 0.23 8.7 6.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_11 PF13086.1 EIW78756.1 - 0.63 9.5 4.0 5.5 6.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 EIW78756.1 - 0.76 9.1 4.0 15 4.9 0.0 3.5 3 2 1 4 4 4 0 AAA-like domain IncA PF04156.9 EIW78756.1 - 1.8 8.1 11.9 4.1 6.9 8.3 1.5 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EIW78756.1 - 4.8 6.1 9.4 9.1 5.2 6.5 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Seryl_tRNA_N PF02403.17 EIW78756.1 - 5.1 7.1 11.9 28 4.7 8.3 2.3 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain SLT PF01464.15 EIW78757.1 - 0.033 13.6 0.1 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 Transglycosylase SLT domain DUF3069 PF11269.3 EIW78757.1 - 0.06 13.4 0.0 0.094 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3069) Glyco_hydro_71 PF03659.9 EIW78758.1 - 5.4e-122 406.9 11.0 6.3e-122 406.7 7.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_hydro_71 PF03659.9 EIW78759.1 - 5.5e-126 420.1 11.3 6.4e-126 419.9 7.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Ribosomal_L37e PF01907.14 EIW78761.1 - 1.7e-19 69.3 12.2 3e-19 68.5 8.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.2 EIW78761.1 - 0.00037 20.2 2.5 0.00054 19.7 1.8 1.3 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 EIW78761.1 - 0.0075 15.9 0.4 0.01 15.5 0.2 1.4 1 1 0 1 1 1 1 SelR domain LIM PF00412.17 EIW78761.1 - 0.022 14.8 2.5 0.033 14.2 1.7 1.3 1 0 0 1 1 1 0 LIM domain HypA PF01155.14 EIW78761.1 - 0.081 12.6 1.6 0.12 12.0 1.1 1.2 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family zf-ribbon_3 PF13248.1 EIW78761.1 - 0.1 11.8 4.2 0.75 9.0 3.1 2.0 1 1 1 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EIW78761.1 - 0.14 12.1 1.7 6.9 6.7 0.3 2.3 1 1 2 3 3 3 0 Zinc ribbon domain zf-RING_5 PF14634.1 EIW78761.1 - 0.45 10.2 4.9 0.72 9.6 3.4 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zinc_ribbon_2 PF13240.1 EIW78761.1 - 0.47 10.0 4.7 1.6 8.2 0.5 2.2 2 0 0 2 2 2 0 zinc-ribbon domain GFA PF04828.9 EIW78761.1 - 0.85 9.6 5.7 1.1 9.2 0.7 2.2 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme zf-C3HC4 PF00097.20 EIW78761.1 - 2.2 7.9 5.8 3.6 7.3 4.0 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW78761.1 - 2.4 8.2 5.6 4 7.5 3.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) YhfH PF14149.1 EIW78761.1 - 3.4 7.5 5.5 3 7.6 0.8 2.2 1 1 1 2 2 2 0 YhfH-like protein Ribosomal_S14 PF00253.16 EIW78761.1 - 4.7 6.6 12.0 3.2 7.2 0.3 2.9 1 1 2 3 3 3 0 Ribosomal protein S14p/S29e VPS9 PF02204.13 EIW78762.1 - 9.4e-18 64.1 0.0 2e-13 50.2 0.0 2.4 2 0 0 2 2 2 2 Vacuolar sorting protein 9 (VPS9) domain Robl_LC7 PF03259.12 EIW78762.1 - 0.00075 19.0 0.0 0.0023 17.4 0.0 1.9 1 0 0 1 1 1 1 Roadblock/LC7 domain Daxx PF03344.10 EIW78762.1 - 2.2 6.6 5.8 3.4 6.0 4.0 1.2 1 0 0 1 1 1 0 Daxx Family Arm PF00514.18 EIW78763.1 - 0.066 13.0 0.7 0.52 10.2 0.0 3.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat PEMT PF04191.8 EIW78764.1 - 1.3e-13 50.9 1.4 2.7e-12 46.7 0.2 2.2 1 1 1 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 EIW78764.1 - 1.4e-11 44.4 1.1 2.4e-10 40.4 0.4 2.5 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 EIW78764.1 - 1.3e-08 33.8 0.6 1.7e-08 33.4 0.4 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EIW78764.1 - 0.0094 15.2 1.2 0.013 14.7 0.8 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) DAO PF01266.19 EIW78766.1 - 6.7e-40 137.0 0.0 8.2e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIW78766.1 - 1.9e-05 24.8 0.0 0.023 14.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW78766.1 - 0.032 14.2 1.1 0.072 13.1 0.1 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain F-box-like PF12937.2 EIW78767.1 - 1.9e-07 30.6 5.0 3.3e-07 29.9 1.6 2.8 2 0 0 2 2 2 1 F-box-like Peptidase_S28 PF05577.7 EIW78768.1 - 2.6e-39 135.0 0.8 8.2e-28 97.1 0.0 3.0 3 0 0 3 3 3 3 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 EIW78768.1 - 0.00013 21.2 0.1 0.00025 20.3 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EIW78768.1 - 0.0004 20.3 0.0 0.00063 19.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW78768.1 - 0.075 12.7 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S28 PF05577.7 EIW78769.1 - 3.4e-51 174.1 1.8 1.3e-50 172.2 1.2 1.7 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 EIW78769.1 - 6.8e-05 22.1 0.2 0.00014 21.1 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EIW78769.1 - 0.00039 20.3 0.0 0.00066 19.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S37 PF05576.6 EIW78769.1 - 0.027 12.9 0.3 0.072 11.5 0.0 1.8 2 0 0 2 2 2 0 PS-10 peptidase S37 Peptidase_S28 PF05577.7 EIW78770.1 - 1.5e-53 181.9 5.4 2.2e-53 181.3 3.7 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 EIW78770.1 - 0.0024 17.1 0.1 0.0049 16.1 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S37 PF05576.6 EIW78770.1 - 0.0087 14.5 0.2 0.014 13.8 0.1 1.5 1 1 0 1 1 1 1 PS-10 peptidase S37 Abhydrolase_6 PF12697.2 EIW78770.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family MCH PF02289.11 EIW78770.1 - 0.018 14.0 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Cyclohydrolase (MCH) Sod_Fe_C PF02777.13 EIW78770.1 - 0.082 12.7 0.3 0.7 9.7 0.1 2.4 2 0 0 2 2 2 0 Iron/manganese superoxide dismutases, C-terminal domain DAO PF01266.19 EIW78771.1 - 2.3e-34 118.8 2.0 3e-34 118.5 1.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW78771.1 - 0.0021 18.0 0.2 0.015 15.2 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIW78771.1 - 0.012 15.6 0.0 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW78771.1 - 0.025 13.6 0.1 0.043 12.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Peptidase_A4 PF01828.12 EIW78772.1 - 1.3e-70 236.6 15.8 1.6e-70 236.3 10.9 1.1 1 0 0 1 1 1 1 Peptidase A4 family Peptidase_S3 PF00944.14 EIW78772.1 - 1.7 8.0 6.1 0.16 11.3 0.6 1.9 2 1 1 3 3 3 0 Alphavirus core protein HDPD PF02924.9 EIW78772.1 - 2.3 8.0 8.4 11 5.8 2.4 2.4 2 0 0 2 2 2 0 Bacteriophage lambda head decoration protein D HET PF06985.6 EIW78776.1 - 3.7e-21 75.7 7.2 6.8e-19 68.4 0.8 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) UQ_con PF00179.21 EIW78777.1 - 7.8e-17 61.0 0.0 8.4e-17 60.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EIW78777.1 - 0.0015 18.4 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EIW78777.1 - 0.036 13.7 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 UEV domain VHS PF00790.14 EIW78778.1 - 3.9e-33 114.0 0.1 6.4e-33 113.3 0.1 1.3 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 EIW78778.1 - 1.1e-15 56.6 0.1 2.1e-15 55.8 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIW78778.1 - 2.4e-15 55.8 0.3 4.2e-15 55.0 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIW78778.1 - 2.9e-12 45.8 0.1 5.6e-12 44.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 EIW78778.1 - 5.9e-08 32.6 0.6 1.7e-07 31.1 0.4 1.8 1 0 0 1 1 1 1 GAT domain UIM PF02809.15 EIW78778.1 - 0.00083 18.7 0.4 0.0027 17.1 0.3 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif Pol_alpha_B_N PF08418.5 EIW78778.1 - 0.0098 15.4 0.2 0.018 14.6 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Med3 PF11593.3 EIW78778.1 - 3.8 6.6 9.0 5.6 6.0 6.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pro_isomerase PF00160.16 EIW78779.1 - 2.2e-40 138.3 0.0 3e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SGT1 PF07093.6 EIW78780.1 - 0.057 11.7 9.8 0.067 11.5 6.8 1.0 1 0 0 1 1 1 0 SGT1 protein UQ_con PF00179.21 EIW78781.1 - 3.8e-23 81.4 0.0 4.5e-23 81.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF4098 PF13345.1 EIW78782.1 - 0.0027 17.5 0.1 0.0027 17.5 0.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4098) TC1 PF15063.1 EIW78782.1 - 0.087 12.3 0.0 0.79 9.3 0.0 2.2 2 0 0 2 2 2 0 Thyroid cancer protein 1 THDPS_M PF14789.1 EIW78782.1 - 0.15 11.9 0.7 28 4.7 0.2 3.2 3 0 0 3 3 3 0 Tetrahydrodipicolinate N-succinyltransferase middle HET PF06985.6 EIW78783.1 - 2.2e-19 70.0 5.1 1.2e-18 67.6 2.9 2.0 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_A4 PF01828.12 EIW78784.1 - 5.1e-75 251.1 13.0 7e-75 250.6 9.0 1.1 1 0 0 1 1 1 1 Peptidase A4 family GST_N_3 PF13417.1 EIW78785.1 - 1.1e-14 54.4 0.0 1.1e-13 51.1 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW78785.1 - 1.7e-10 40.7 0.0 2.9e-09 36.7 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW78785.1 - 3.9e-06 26.6 0.0 1.1e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW78785.1 - 1.6e-05 25.0 0.0 7.1e-05 22.9 0.0 2.1 2 1 1 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW78785.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW78785.1 - 0.029 14.8 0.0 0.043 14.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MaoC_dehydrat_N PF13452.1 EIW78785.1 - 0.13 12.0 0.0 1 9.1 0.0 2.1 2 0 0 2 2 2 0 N-terminal half of MaoC dehydratase DUF3487 PF11990.3 EIW78786.1 - 5.5 6.4 8.7 1.4 8.3 0.4 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3487) ABC2_membrane_4 PF12730.2 EIW78787.1 - 0.14 11.2 12.6 0.071 12.2 5.1 2.0 2 0 0 2 2 2 0 ABC-2 family transporter protein Reticulon PF02453.12 EIW78787.1 - 0.98 9.0 6.2 1.2 8.6 2.2 2.1 2 0 0 2 2 2 0 Reticulon Tmemb_170 PF10190.4 EIW78787.1 - 4.2 7.4 9.3 0.15 12.0 1.2 1.9 2 0 0 2 2 2 0 Putative transmembrane protein 170 GATA PF00320.22 EIW78788.1 - 1.3e-29 101.1 14.8 1.8e-15 55.9 2.4 2.5 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EIW78788.1 - 0.0081 15.4 10.7 0.018 14.3 0.4 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding NMD3 PF04981.8 EIW78788.1 - 0.04 13.0 1.1 5.6 6.0 0.0 2.4 2 0 0 2 2 2 0 NMD3 family eIF-5_eIF-2B PF01873.12 EIW78788.1 - 0.22 11.2 7.9 1.5 8.4 0.7 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 RRN7 PF11781.3 EIW78788.1 - 2.6 7.6 10.7 0.6 9.6 1.0 2.7 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 Elf1 PF05129.8 EIW78788.1 - 3.3 7.4 8.8 0.54 9.9 0.7 2.6 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like COPI_assoc PF08507.5 EIW78791.1 - 0.57 9.8 7.6 1 9.0 5.2 1.4 1 0 0 1 1 1 0 COPI associated protein WEMBL PF05701.6 EIW78795.1 - 0.042 12.3 1.5 0.049 12.0 1.0 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Dimer_Tnp_hAT PF05699.9 EIW78803.1 - 4.3e-08 32.6 0.0 4.4e-08 32.6 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region LT-IIB PF06453.6 EIW78803.1 - 0.066 12.8 0.1 0.071 12.7 0.1 1.0 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) Opi1 PF08618.5 EIW78804.1 - 1.4e-64 218.6 32.3 1.1e-53 182.6 6.4 4.3 2 1 1 3 3 3 2 Transcription factor Opi1 Perilipin PF03036.11 EIW78804.1 - 9.7e-06 24.6 0.1 0.0001 21.2 0.0 2.3 2 0 0 2 2 2 1 Perilipin family zf-C2H2 PF00096.21 EIW78805.1 - 0.00025 21.1 2.7 0.0005 20.2 1.9 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW78805.1 - 0.017 15.4 2.0 0.034 14.4 1.4 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Ogr_Delta PF04606.7 EIW78805.1 - 0.056 13.0 0.1 0.084 12.5 0.1 1.3 1 0 0 1 1 1 0 Ogr/Delta-like zinc finger Zn_Tnp_IS1595 PF12760.2 EIW78809.1 - 0.37 10.6 2.1 0.72 9.7 1.4 1.5 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Opi1 PF08618.5 EIW78813.1 - 4.7e-55 187.2 23.7 2.7e-42 145.1 0.1 4.1 3 1 1 4 4 4 3 Transcription factor Opi1 Glyco_hydro_67C PF07477.7 EIW78815.1 - 0.055 12.8 0.1 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 C-terminus KxDL PF10241.4 EIW78815.1 - 0.15 12.0 0.7 0.28 11.1 0.5 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein Transposase_21 PF02992.9 EIW78817.1 - 8.8e-07 28.2 0.0 1.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EIW78817.1 - 4.2e-05 23.0 0.1 7.3e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) PHBC_N PF12551.3 EIW78821.1 - 0.078 12.5 0.4 0.14 11.6 0.2 1.4 1 0 0 1 1 1 0 Poly-beta-hydroxybutyrate polymerase N terminal GP3 PF03076.9 EIW78821.1 - 0.58 9.9 3.4 2.6 7.8 0.2 2.5 1 1 2 3 3 3 0 Equine arteritis virus GP3 DHHA2 PF02833.9 EIW78822.1 - 1.4e-08 34.9 0.0 6.6e-08 32.8 0.0 2.1 1 1 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EIW78822.1 - 3.2e-08 33.3 0.0 7e-08 32.2 0.0 1.5 2 0 0 2 2 2 1 DHH family CFEM PF05730.6 EIW78823.1 - 0.00013 21.7 9.0 0.00023 20.8 6.2 1.4 1 0 0 1 1 1 1 CFEM domain Glyco_hydro_71 PF03659.9 EIW78824.1 - 2.3e-115 385.1 9.3 2.6e-115 384.9 6.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 O-FucT PF10250.4 EIW78825.1 - 6.1e-08 32.1 0.0 2.1e-07 30.3 0.0 1.7 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase CFEM PF05730.6 EIW78826.1 - 0.015 15.1 13.9 0.03 14.1 9.6 1.6 1 1 1 2 2 2 0 CFEM domain DUF2673 PF10880.3 EIW78826.1 - 0.42 10.6 1.9 0.66 10.0 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) PepSY_2 PF13670.1 EIW78826.1 - 1.6 8.6 5.0 0.29 11.0 0.8 1.8 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain C8 PF08742.6 EIW78826.1 - 3.4 7.9 8.1 1.2 9.4 2.6 2.2 1 1 1 2 2 2 0 C8 domain LRR_8 PF13855.1 EIW78828.1 - 0.0043 16.7 2.1 3.7 7.3 0.1 4.9 4 2 1 5 5 5 2 Leucine rich repeat Gly_transf_sug PF04488.10 EIW78831.1 - 3.1e-07 30.7 0.0 4.9e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EIW78831.1 - 0.0038 16.4 0.6 0.0058 15.8 0.4 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Lipase_GDSL_2 PF13472.1 EIW78832.1 - 0.0087 16.2 0.0 0.0088 16.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ICMT PF04140.9 EIW78834.1 - 8.5e-14 51.5 0.8 1.1e-12 48.0 0.0 2.8 4 0 0 4 4 4 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIW78834.1 - 7.7e-12 45.2 0.6 1.2e-09 38.1 0.0 2.7 3 0 0 3 3 3 2 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EIW78834.1 - 1.7e-07 30.1 0.1 3.7e-07 29.0 0.0 1.6 2 0 0 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family BCD PF15461.1 EIW78834.1 - 0.12 11.8 5.4 0.03 13.7 1.4 1.7 1 1 1 2 2 2 0 Beta-carotene 15,15'-dioxygenase Mit_proteolip PF08039.6 EIW78835.1 - 0.027 14.4 0.2 0.059 13.3 0.2 1.5 1 0 0 1 1 1 0 Mitochondrial proteolipid STE2 PF02116.10 EIW78835.1 - 0.034 13.1 2.9 0.039 13.0 2.0 1.0 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR DUF998 PF06197.8 EIW78835.1 - 0.14 11.4 2.8 0.21 10.8 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF2530 PF10745.4 EIW78835.1 - 0.16 11.9 0.9 0.28 11.2 0.4 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2530) DUF2157 PF09925.4 EIW78835.1 - 0.28 10.7 3.5 0.13 11.8 0.5 1.7 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) adh_short PF00106.20 EIW78836.1 - 3e-16 59.8 0.9 4.7e-16 59.1 0.3 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW78836.1 - 1.1e-05 25.2 0.3 3.5e-05 23.5 0.1 1.8 2 0 0 2 2 2 1 KR domain Ribosomal_L35Ae PF01247.13 EIW78837.1 - 1.5e-42 143.3 0.4 1.6e-42 143.1 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EIW78837.1 - 0.00051 19.9 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 2 RimM N-terminal domain Barwin PF00967.12 EIW78838.1 - 0.0075 15.9 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 Barwin family DPBB_1 PF03330.13 EIW78838.1 - 0.067 13.1 0.0 0.17 11.9 0.0 1.6 1 1 0 1 1 1 0 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Exo_endo_phos PF03372.18 EIW78839.1 - 2.1e-15 57.3 0.1 3.9e-15 56.4 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIW78839.1 - 1.5e-09 37.5 0.0 2.8e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase zf-GRF PF06839.7 EIW78839.1 - 7.7e-09 35.3 2.5 5e-06 26.3 0.2 2.5 2 0 0 2 2 2 2 GRF zinc finger Spuma_A9PTase PF03539.9 EIW78839.1 - 0.027 14.3 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) WD40 PF00400.27 EIW78840.1 - 2e-17 62.2 2.8 1.9e-06 27.5 0.0 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat zf-C2H2_jaz PF12171.3 EIW78841.1 - 1.6e-09 37.5 5.3 3.4e-09 36.5 3.7 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EIW78841.1 - 0.013 15.6 0.1 0.018 15.1 0.1 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EIW78841.1 - 0.5 10.8 2.1 0.99 9.8 1.5 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW78841.1 - 0.9 10.0 3.0 2.3 8.7 2.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-met PF12874.2 EIW78841.1 - 2.7 8.3 6.8 0.44 10.8 2.1 1.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Ecl1 PF12855.2 EIW78842.1 - 3.4 7.0 11.4 0.12 11.6 0.3 3.2 3 0 0 3 3 3 0 Life-span regulatory factor THOC7 PF05615.8 EIW78843.1 - 0.015 15.5 9.4 0.015 15.5 6.5 3.0 1 1 2 3 3 3 0 Tho complex subunit 7 CENP-F_leu_zip PF10473.4 EIW78843.1 - 0.016 15.0 12.7 0.016 15.0 8.8 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2951 PF11166.3 EIW78843.1 - 0.056 13.3 0.2 0.056 13.3 0.1 4.0 1 1 2 4 4 4 0 Protein of unknown function (DUF2951) DUF573 PF04504.9 EIW78843.1 - 0.096 12.9 0.4 0.096 12.9 0.3 2.9 2 2 1 3 3 3 0 Protein of unknown function, DUF573 DUF3316 PF11777.3 EIW78843.1 - 0.21 11.3 1.4 0.45 10.3 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3316) Spc7 PF08317.6 EIW78843.1 - 0.26 9.9 34.3 0.046 12.3 12.7 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein HALZ PF02183.13 EIW78843.1 - 1 9.1 39.9 1.1 8.9 0.6 7.1 5 2 2 7 7 7 0 Homeobox associated leucine zipper Bacillus_HBL PF05791.6 EIW78843.1 - 1.2 8.4 26.3 0.12 11.7 3.3 3.3 2 2 1 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DUF3584 PF12128.3 EIW78843.1 - 1.5 6.0 40.4 1.7 5.8 28.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF904 PF06005.7 EIW78843.1 - 3.6 7.9 45.2 11 6.3 4.8 4.7 1 1 1 3 3 3 0 Protein of unknown function (DUF904) CCDC155 PF14662.1 EIW78843.1 - 4.3 6.8 44.8 4.4 6.8 4.7 3.6 1 1 3 4 4 4 0 Coiled-coil region of CCDC155 ADIP PF11559.3 EIW78843.1 - 6.5 6.6 49.9 2.5 7.9 1.3 4.7 1 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding Dfp1_Him1_M PF08630.5 EIW78843.1 - 9.5 6.0 13.8 1 9.1 1.8 2.8 1 1 1 2 2 2 0 Dfp1/Him1, central region Reo_sigmaC PF04582.7 EIW78843.1 - 9.7 5.2 7.7 2.8 7.0 0.3 2.4 1 1 0 2 2 2 0 Reovirus sigma C capsid protein YfhO PF09586.5 EIW78844.1 - 2.1 6.2 9.2 7.4 4.4 6.4 1.9 1 1 0 1 1 1 0 Bacterial membrane protein YfhO Acetyltransf_4 PF13420.1 EIW78845.1 - 0.0082 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GST_N_3 PF13417.1 EIW78846.1 - 4.4e-13 49.2 0.0 8.7e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW78846.1 - 6.9e-10 38.7 0.0 2e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW78846.1 - 5.6e-06 26.1 0.2 1.7e-05 24.5 0.1 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW78846.1 - 2e-05 24.7 0.0 3.9e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW78846.1 - 0.00091 19.1 0.0 0.0035 17.2 0.0 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW78846.1 - 0.023 15.1 0.2 0.14 12.6 0.0 2.0 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain Kinesin PF00225.18 EIW78847.1 - 1.9e-101 339.1 0.0 2.8e-101 338.5 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Transposase_22 PF02994.9 EIW78847.1 - 2.5e-05 22.9 1.8 3.8e-05 22.3 1.2 1.1 1 0 0 1 1 1 1 L1 transposable element Reo_sigmaC PF04582.7 EIW78847.1 - 0.0087 15.2 2.4 0.029 13.5 0.5 2.3 2 0 0 2 2 2 1 Reovirus sigma C capsid protein V-SNARE PF05008.10 EIW78847.1 - 0.0098 16.0 0.5 0.0098 16.0 0.3 2.6 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus Fib_alpha PF08702.5 EIW78847.1 - 0.045 13.8 1.5 0.089 12.9 1.1 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.14 EIW78847.1 - 0.16 9.8 5.8 0.24 9.2 4.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GAS PF13851.1 EIW78847.1 - 0.23 10.6 10.9 0.42 9.7 7.6 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Bacillus_HBL PF05791.6 EIW78847.1 - 0.29 10.5 1.7 0.64 9.3 0.8 1.9 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) ATG16 PF08614.6 EIW78847.1 - 0.48 10.2 23.1 2.3 8.0 14.0 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF972 PF06156.8 EIW78847.1 - 0.86 9.9 10.9 49 4.3 2.7 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF972) DUF812 PF05667.6 EIW78847.1 - 1.3 7.4 16.5 2.2 6.7 11.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) AAA_10 PF12846.2 EIW78847.1 - 1.6 8.0 4.3 16 4.8 0.1 2.6 2 1 0 2 2 2 0 AAA-like domain Peptidase_S46 PF10459.4 EIW78847.1 - 2.4 6.4 13.3 3.9 5.7 9.2 1.2 1 0 0 1 1 1 0 Peptidase S46 TMF_DNA_bd PF12329.3 EIW78847.1 - 2.5 7.9 12.6 13 5.6 5.8 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF87 PF01935.12 EIW78847.1 - 2.5 7.8 5.1 1.5 8.5 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function DUF87 zf-C4H2 PF10146.4 EIW78847.1 - 2.8 7.8 10.6 0.16 11.9 1.7 2.7 3 0 0 3 3 3 0 Zinc finger-containing protein DivIC PF04977.10 EIW78847.1 - 5.3 6.5 11.3 0.38 10.2 1.5 2.8 2 1 0 2 2 2 0 Septum formation initiator ADIP PF11559.3 EIW78847.1 - 6.8 6.5 18.1 4.6 7.1 4.2 2.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DAP3 PF10236.4 EIW78848.1 - 1.6e-55 188.2 0.0 2e-55 187.8 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 EIW78848.1 - 7.7e-06 26.0 0.5 2.3e-05 24.4 0.1 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EIW78848.1 - 0.00047 19.6 0.1 0.0036 16.7 0.1 2.3 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EIW78848.1 - 0.019 14.6 0.0 0.076 12.6 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 EIW78848.1 - 0.12 12.4 0.0 1.6 8.8 0.0 2.3 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 EIW78848.1 - 0.13 11.1 0.0 3.5 6.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PSI_8 PF00796.13 EIW78849.1 - 0.079 12.5 0.9 0.079 12.5 0.6 1.9 2 0 0 2 2 2 0 Photosystem I reaction centre subunit VIII Mit_proteolip PF08039.6 EIW78849.1 - 0.11 12.4 0.3 0.56 10.2 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial proteolipid PSI_8 PF00796.13 EIW78851.1 - 0.067 12.7 3.7 0.22 11.1 2.6 1.9 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VIII TraE PF05309.6 EIW78851.1 - 0.16 11.0 0.3 0.55 9.3 0.0 1.9 2 0 0 2 2 2 0 TraE protein Cornichon PF03311.9 EIW78851.1 - 1.8 8.6 6.6 19 5.4 2.3 2.8 2 1 0 2 2 2 0 Cornichon protein Asp PF00026.18 EIW78854.1 - 2.8e-14 53.0 1.0 3.1e-14 52.9 0.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease ArgJ PF01960.13 EIW78855.1 - 2.6e-123 411.2 0.0 5.6e-70 235.7 0.0 3.3 3 1 0 3 3 3 3 ArgJ family Catalase PF00199.14 EIW78857.1 - 2.1e-177 589.5 0.6 2.8e-177 589.1 0.4 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EIW78857.1 - 1.3e-18 66.6 0.0 3.8e-18 65.1 0.0 1.8 1 0 0 1 1 1 1 Catalase-related immune-responsive ArgJ PF01960.13 EIW78859.1 - 3.1e-18 65.3 0.0 3.7e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 ArgJ family PgaD PF13994.1 EIW78860.1 - 0.086 12.3 1.0 0.12 11.8 0.7 1.3 1 0 0 1 1 1 0 PgaD-like protein DUF805 PF05656.9 EIW78860.1 - 0.5 10.2 5.3 0.35 10.6 2.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF805) FAD_binding_3 PF01494.14 EIW78862.1 - 5.8e-23 81.5 0.1 1.3e-15 57.3 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EIW78862.1 - 4.5e-13 48.8 3.7 1.9e-06 27.0 0.5 2.5 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EIW78862.1 - 1.9e-09 36.4 0.2 1.8e-05 23.3 0.2 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 EIW78862.1 - 3.4e-09 36.0 1.2 6.1e-08 31.9 0.4 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EIW78862.1 - 1.5e-08 34.9 0.8 0.00029 21.1 0.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW78862.1 - 3.5e-08 33.5 0.1 1.5e-07 31.4 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIW78862.1 - 3.5e-07 29.2 0.4 2e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.1 EIW78862.1 - 2.1e-06 27.6 1.5 9.1e-06 25.6 0.2 2.5 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIW78862.1 - 6.9e-06 26.2 0.0 1.8e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIW78862.1 - 8.6e-06 24.8 0.1 0.0003 19.7 0.2 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EIW78862.1 - 2.8e-05 23.4 1.3 7.8e-05 21.9 0.9 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase UDPG_MGDP_dh_N PF03721.9 EIW78862.1 - 0.0009 18.6 0.6 0.0015 17.9 0.4 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Thi4 PF01946.12 EIW78862.1 - 0.0012 17.9 0.4 0.0053 15.8 0.2 1.9 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.19 EIW78862.1 - 0.0018 17.4 0.0 0.31 10.0 0.0 2.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EIW78862.1 - 0.0042 16.0 0.8 0.027 13.4 0.5 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 EIW78862.1 - 0.046 13.4 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EIW78862.1 - 0.056 13.0 0.2 0.093 12.3 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EIW78862.1 - 0.1 12.5 0.2 0.24 11.3 0.2 1.6 1 0 0 1 1 1 0 NADH(P)-binding Phage_holin_4 PF05105.7 EIW78863.1 - 0.044 13.4 0.7 1.4 8.6 0.1 2.2 2 0 0 2 2 2 0 Holin family FAD_binding_3 PF01494.14 EIW78864.1 - 0.0014 17.7 0.0 0.0016 17.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain GATA PF00320.22 EIW78866.1 - 1.9e-09 36.6 6.4 3.6e-09 35.8 4.4 1.5 1 0 0 1 1 1 1 GATA zinc finger Gasdermin PF04598.7 EIW78867.1 - 0.12 11.0 0.0 0.12 11.0 0.0 1.0 1 0 0 1 1 1 0 Gasdermin family PX PF00787.19 EIW78868.1 - 4.8e-13 48.8 0.1 9.5e-13 47.9 0.0 1.5 2 0 0 2 2 2 1 PX domain FAD_binding_3 PF01494.14 EIW78870.1 - 9.5e-14 51.2 0.0 9.8e-07 28.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EIW78870.1 - 0.00056 18.9 0.1 0.0012 17.8 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EIW78870.1 - 0.004 15.8 0.0 0.0056 15.3 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase HI0933_like PF03486.9 EIW78870.1 - 0.067 11.6 0.0 0.093 11.1 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein DUF2279 PF10043.4 EIW78872.1 - 0.13 12.5 0.0 0.45 10.8 0.0 1.9 2 0 0 2 2 2 0 Predicted periplasmic lipoprotein (DUF2279) Glycos_transf_4 PF00953.16 EIW78872.1 - 2 8.2 10.4 19 5.0 7.0 2.6 1 1 0 1 1 1 0 Glycosyl transferase family 4 FAD_binding_3 PF01494.14 EIW78875.1 - 3.1e-15 56.0 0.2 2.1e-14 53.3 0.2 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIW78875.1 - 1.4e-12 47.2 0.9 8.8e-06 24.8 0.0 2.1 1 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW78875.1 - 1.4e-08 34.0 0.0 9.3e-08 31.3 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EIW78875.1 - 2.3e-08 34.1 1.1 3.9e-07 30.1 0.8 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW78875.1 - 7.8e-07 27.9 0.1 0.00039 19.0 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.22 EIW78875.1 - 1.4e-06 28.6 0.6 0.0053 17.1 0.2 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW78875.1 - 1.5e-05 24.8 0.1 4.5e-05 23.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EIW78875.1 - 2.4e-05 23.6 0.0 3.9e-05 22.9 0.0 1.3 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIW78875.1 - 7.9e-05 21.7 0.1 0.00019 20.5 0.0 1.5 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EIW78875.1 - 0.012 14.7 0.2 0.052 12.6 0.0 2.0 2 1 0 2 2 2 0 Thi4 family Amino_oxidase PF01593.19 EIW78875.1 - 0.043 12.8 0.0 1.9 7.4 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 EIW78875.1 - 0.047 12.3 0.5 0.39 9.2 0.0 2.0 1 1 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 EIW78875.1 - 0.05 12.4 0.7 0.076 11.8 0.5 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EIW78875.1 - 0.083 12.9 0.2 0.47 10.4 0.1 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SNARE_assoc PF09335.6 EIW78876.1 - 1.1e-17 64.3 6.7 2.8e-17 63.0 4.6 1.7 1 0 0 1 1 1 1 SNARE associated Golgi protein 7TM_GPCR_Srd PF10317.4 EIW78876.1 - 0.024 13.6 1.5 0.11 11.4 0.4 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srd F-box-like PF12937.2 EIW78877.1 - 0.00076 19.1 0.1 0.002 17.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIW78877.1 - 0.0012 18.3 2.6 0.26 10.9 0.1 4.3 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) F-box PF00646.28 EIW78877.1 - 0.0099 15.5 0.1 0.025 14.2 0.0 1.7 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.1 EIW78877.1 - 0.051 13.6 0.9 20 5.6 0.0 4.1 4 0 0 4 4 4 0 Leucine Rich repeat FluMu_gp41 PF10109.4 EIW78877.1 - 0.15 11.9 0.0 0.62 10.0 0.0 2.0 2 0 0 2 2 2 0 Mu-like prophage FluMu protein gp41 FAD_binding_3 PF01494.14 EIW78878.1 - 2.1e-18 66.5 3.1 3.8e-12 45.9 0.6 2.7 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EIW78878.1 - 2.2e-10 39.9 0.5 3.5e-06 26.1 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW78878.1 - 7.8e-09 34.8 1.6 9.4e-08 31.3 0.4 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EIW78878.1 - 2.6e-06 27.3 0.1 8.2e-06 25.7 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIW78878.1 - 3e-06 27.5 1.4 0.0027 18.0 0.5 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW78878.1 - 5.5e-06 26.3 0.8 3e-05 24.0 0.3 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIW78878.1 - 2.5e-05 23.5 0.0 3.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EIW78878.1 - 0.00035 19.1 0.7 0.00047 18.7 0.1 1.4 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EIW78878.1 - 0.0067 15.3 0.3 0.0092 14.8 0.2 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 EIW78878.1 - 0.052 12.6 0.3 0.11 11.5 0.2 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 EIW78878.1 - 0.069 11.7 0.6 1.1 7.8 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase Amino_oxidase PF01593.19 EIW78878.1 - 0.076 12.0 0.0 5.1 6.0 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EIW78878.1 - 0.1 11.4 0.4 0.2 10.5 0.3 1.6 1 1 0 1 1 1 0 Lycopene cyclase protein Thiolase_N PF00108.18 EIW78879.1 - 7.9e-84 280.7 3.4 7.9e-84 280.7 2.4 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EIW78879.1 - 4.7e-41 139.0 0.3 8.3e-41 138.2 0.2 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EIW78879.1 - 0.04 13.3 1.8 0.12 11.7 0.3 2.5 3 0 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain Zn_clus PF00172.13 EIW78881.1 - 3e-06 27.0 12.8 5.7e-06 26.1 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PDH PF02153.12 EIW78883.1 - 5.1e-12 45.2 0.0 7.9e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_binding_2 PF03446.10 EIW78883.1 - 1.8e-07 31.1 0.0 3.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EIW78883.1 - 1.7e-06 28.3 0.0 8.8e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EIW78883.1 - 0.047 13.1 0.0 0.077 12.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EIW78883.1 - 0.062 13.1 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.15 EIW78883.1 - 0.088 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EIW78883.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Thymidylate_kin PF02223.12 EIW78885.1 - 4e-42 143.6 0.0 4.7e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_14 PF13173.1 EIW78885.1 - 0.057 13.3 0.1 0.32 10.9 0.0 1.9 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 EIW78885.1 - 0.071 12.3 0.1 0.27 10.4 0.0 1.9 2 1 0 2 2 2 0 ADP-ribosylation factor family KTI12 PF08433.5 EIW78885.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.7 1 1 0 1 1 1 0 Chromatin associated protein KTI12 NACHT PF05729.7 EIW78886.1 - 1.5e-07 31.1 0.3 3.7e-06 26.7 0.0 2.9 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EIW78886.1 - 2.3e-07 30.9 1.8 4.2e-07 30.1 0.2 2.2 2 0 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EIW78886.1 - 2.8e-05 23.9 0.0 9.7e-05 22.1 0.0 1.8 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 EIW78886.1 - 7.5e-05 22.8 0.0 0.00027 21.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EIW78886.1 - 0.00043 20.4 0.0 0.0017 18.5 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EIW78886.1 - 0.0019 18.3 0.0 0.005 16.9 0.0 1.7 1 0 0 1 1 1 1 RNA helicase APS_kinase PF01583.15 EIW78886.1 - 0.042 13.5 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase IstB_IS21 PF01695.12 EIW78886.1 - 0.05 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 EIW78886.1 - 0.051 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF258 PF03193.11 EIW78886.1 - 0.062 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 TFIID_30kDa PF03540.8 EIW78886.1 - 0.086 12.6 0.0 18 5.2 0.0 2.7 2 0 0 2 2 2 0 Transcription initiation factor TFIID 23-30kDa subunit Zeta_toxin PF06414.7 EIW78886.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 EIW78886.1 - 0.12 12.6 0.0 0.3 11.3 0.0 1.5 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.8 EIW78886.1 - 0.13 10.9 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Parvo_NS1 PF01057.12 EIW78886.1 - 0.15 10.8 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.11 EIW78886.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Pet20 PF08692.5 EIW78886.1 - 0.23 11.3 0.0 0.64 9.9 0.0 1.6 2 0 0 2 2 1 0 Mitochondrial protein Pet20 FAD_binding_3 PF01494.14 EIW78888.1 - 1.2e-09 37.7 0.2 1.7e-09 37.2 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIW78888.1 - 0.0054 15.6 0.0 0.0061 15.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase IGR PF09597.5 EIW78888.1 - 0.091 12.6 0.0 6 6.8 0.0 2.3 2 0 0 2 2 2 0 IGR protein motif NACHT PF05729.7 EIW78892.1 - 1.3e-10 41.1 0.1 4.2e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EIW78892.1 - 6.3e-09 36.0 0.7 1.3e-08 35.0 0.1 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EIW78892.1 - 8.6e-07 29.1 0.0 4.2e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EIW78892.1 - 1.4e-05 25.2 0.0 4.5e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EIW78892.1 - 5.4e-05 23.0 0.0 9.2e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase APS_kinase PF01583.15 EIW78892.1 - 0.0001 21.9 0.0 0.00028 20.5 0.1 1.6 2 0 0 2 2 1 1 Adenylylsulphate kinase RNA_helicase PF00910.17 EIW78892.1 - 0.0013 18.9 0.0 0.0037 17.4 0.0 1.8 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 EIW78892.1 - 0.0014 17.7 0.7 0.0048 16.0 0.1 2.0 2 0 0 2 2 2 1 Zeta toxin TIP49 PF06068.8 EIW78892.1 - 0.0017 17.1 0.0 0.044 12.4 0.0 2.1 2 0 0 2 2 2 1 TIP49 C-terminus KAP_NTPase PF07693.9 EIW78892.1 - 0.01 14.8 0.2 0.36 9.7 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain T2SE PF00437.15 EIW78892.1 - 0.012 14.5 0.2 0.03 13.2 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.1 EIW78892.1 - 0.016 15.5 0.0 0.038 14.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EIW78892.1 - 0.027 13.4 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 EIW78892.1 - 0.027 13.8 0.0 0.15 11.4 0.0 2.1 1 1 1 2 2 2 0 AAA-like domain Sigma54_activ_2 PF14532.1 EIW78892.1 - 0.032 14.2 0.1 0.088 12.8 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 EIW78892.1 - 0.035 14.3 0.0 0.093 13.0 0.0 1.7 2 0 0 2 2 1 0 ABC transporter AAA_33 PF13671.1 EIW78892.1 - 0.04 13.7 0.0 0.087 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIW78892.1 - 0.046 12.9 0.1 0.3 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 PRK PF00485.13 EIW78892.1 - 0.047 13.2 0.0 0.081 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EIW78892.1 - 0.05 14.4 0.0 0.11 13.3 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIW78892.1 - 0.056 12.9 0.1 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain UPF0079 PF02367.12 EIW78892.1 - 0.057 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 EIW78892.1 - 0.075 12.5 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF3549 PF12069.3 EIW78892.1 - 0.098 11.4 0.0 0.39 9.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3549) Torsin PF06309.6 EIW78892.1 - 0.12 12.2 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 Torsin FAD_binding_3 PF01494.14 EIW78894.1 - 0.084 11.9 0.6 0.69 8.8 0.4 1.9 1 1 0 1 1 1 0 FAD binding domain NACHT PF05729.7 EIW78895.1 - 2.8e-07 30.3 0.0 4.2e-07 29.7 0.0 1.3 1 1 0 1 1 1 1 NACHT domain APS_kinase PF01583.15 EIW78895.1 - 2.2e-05 24.1 0.1 3.6e-05 23.4 0.1 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.1 EIW78895.1 - 5.2e-05 23.3 0.0 5.6e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW78895.1 - 5.4e-05 23.3 0.0 5.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EIW78895.1 - 0.00019 21.5 0.0 0.00029 20.9 0.0 1.3 1 0 0 1 1 1 1 RNA helicase PRK PF00485.13 EIW78895.1 - 0.0038 16.8 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family DUF2075 PF09848.4 EIW78895.1 - 0.012 14.6 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.8 EIW78895.1 - 0.012 14.3 0.0 0.012 14.3 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus AAA_18 PF13238.1 EIW78895.1 - 0.019 15.2 0.0 0.024 14.9 0.0 1.3 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EIW78895.1 - 0.02 14.5 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 EIW78895.1 - 0.026 14.7 0.0 0.042 14.0 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EIW78895.1 - 0.028 14.3 0.0 0.031 14.1 0.0 1.2 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIW78895.1 - 0.041 14.1 0.0 0.094 13.0 0.0 1.3 1 1 0 1 1 1 0 ABC transporter T2SE PF00437.15 EIW78895.1 - 0.046 12.6 0.1 0.082 11.7 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 EIW78895.1 - 0.046 12.8 0.0 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EIW78895.1 - 0.048 14.4 0.0 0.059 14.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIW78895.1 - 0.077 12.5 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cytidylate_kin2 PF13189.1 EIW78895.1 - 0.083 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family Arch_ATPase PF01637.13 EIW78895.1 - 0.085 12.5 0.0 0.09 12.4 0.0 1.1 1 0 0 1 1 1 0 Archaeal ATPase Torsin PF06309.6 EIW78895.1 - 0.15 11.9 0.1 0.23 11.3 0.0 1.5 1 1 0 1 1 1 0 Torsin CbiA PF01656.18 EIW78895.1 - 0.17 11.2 0.1 0.3 10.4 0.1 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NACHT PF05729.7 EIW78896.1 - 2.9e-08 33.5 0.0 6.1e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW78896.1 - 3.6e-06 27.0 1.1 1.1e-05 25.5 0.8 1.9 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EIW78896.1 - 9.6e-06 25.4 0.0 1.6e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA PF00004.24 EIW78896.1 - 0.0001 22.4 0.0 0.00034 20.8 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIW78896.1 - 0.00015 21.8 0.0 0.0011 19.1 0.0 2.4 2 2 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EIW78896.1 - 0.0038 18.0 0.1 0.016 16.0 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EIW78896.1 - 0.009 16.3 0.0 0.029 14.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EIW78896.1 - 0.01 15.9 0.3 0.27 11.2 0.0 3.1 4 0 0 4 4 4 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 EIW78896.1 - 0.01 14.9 0.1 0.02 13.9 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin UPF0079 PF02367.12 EIW78896.1 - 0.021 14.4 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 EIW78896.1 - 0.022 14.2 0.1 0.045 13.2 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain APS_kinase PF01583.15 EIW78896.1 - 0.031 13.9 0.1 0.053 13.1 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase FtsK_SpoIIIE PF01580.13 EIW78896.1 - 0.035 13.5 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family Sigma54_activat PF00158.21 EIW78896.1 - 0.035 13.5 0.0 0.074 12.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 EIW78896.1 - 0.041 14.1 0.0 0.077 13.2 0.0 1.5 1 0 0 1 1 1 0 ABC transporter KaiC PF06745.8 EIW78896.1 - 0.042 12.9 0.1 0.73 8.8 0.1 2.2 2 0 0 2 2 2 0 KaiC RNA_helicase PF00910.17 EIW78896.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_10 PF12846.2 EIW78896.1 - 0.075 12.4 0.6 0.2 11.0 0.1 1.8 2 1 0 2 2 2 0 AAA-like domain IstB_IS21 PF01695.12 EIW78896.1 - 0.087 12.2 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_PrkA PF08298.6 EIW78896.1 - 0.094 11.3 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain TIP49 PF06068.8 EIW78896.1 - 0.12 11.0 0.1 0.18 10.4 0.1 1.1 1 0 0 1 1 1 0 TIP49 C-terminus AAA_33 PF13671.1 EIW78896.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_5 PF07728.9 EIW78896.1 - 0.14 11.9 0.1 0.45 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 EIW78896.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF258 PF03193.11 EIW78896.1 - 0.17 11.0 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EIW78896.1 - 0.21 11.8 0.1 1.2 9.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EIW78903.1 - 9.7e-10 38.3 0.0 3.5e-09 36.5 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EIW78903.1 - 4.7e-06 26.7 1.0 1.6e-05 24.9 0.2 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EIW78903.1 - 0.0002 21.5 0.0 0.00048 20.3 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 EIW78903.1 - 0.00038 20.1 0.1 0.00074 19.1 0.1 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.17 EIW78903.1 - 0.0013 18.8 0.6 0.011 15.8 0.0 2.6 3 0 0 3 3 2 1 RNA helicase AAA_22 PF13401.1 EIW78903.1 - 0.0015 18.6 0.0 0.0053 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EIW78903.1 - 0.0032 17.1 0.0 0.0058 16.3 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase Zeta_toxin PF06414.7 EIW78903.1 - 0.012 14.7 0.5 0.026 13.6 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.1 EIW78903.1 - 0.039 14.2 0.0 0.11 12.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EIW78903.1 - 0.069 12.7 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activ_2 PF14532.1 EIW78903.1 - 0.1 12.6 0.1 0.72 9.8 0.0 2.3 3 0 0 3 3 2 0 Sigma-54 interaction domain PRK PF00485.13 EIW78903.1 - 0.14 11.6 0.1 0.27 10.7 0.1 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.22 EIW78903.1 - 0.15 12.3 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 ABC transporter DUF2075 PF09848.4 EIW78903.1 - 0.17 10.8 0.0 1 8.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) TIP49 PF06068.8 EIW78903.1 - 0.26 9.9 0.1 0.42 9.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus T2SE PF00437.15 EIW78903.1 - 0.27 10.1 0.0 0.49 9.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein zf-nanos PF05741.8 EIW78904.1 - 0.023 14.6 0.5 0.046 13.7 0.3 1.6 1 1 0 1 1 1 0 Nanos RNA binding domain NACHT PF05729.7 EIW78906.1 - 2.8e-09 36.8 0.0 6.8e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW78906.1 - 1.5e-06 28.3 1.6 4.2e-06 26.8 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EIW78906.1 - 4.9e-05 23.1 0.0 7.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EIW78906.1 - 8.8e-05 22.6 0.1 0.00059 19.9 0.0 2.4 1 1 2 3 3 3 1 AAA domain RNA_helicase PF00910.17 EIW78906.1 - 0.00058 19.9 0.1 0.0065 16.6 0.0 2.5 2 1 1 3 3 3 1 RNA helicase APS_kinase PF01583.15 EIW78906.1 - 0.00071 19.2 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA PF00004.24 EIW78906.1 - 0.00089 19.4 0.0 0.0031 17.7 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EIW78906.1 - 0.0017 17.4 0.0 0.0034 16.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin PRK PF00485.13 EIW78906.1 - 0.0084 15.6 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EIW78906.1 - 0.042 14.1 0.0 0.093 13.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIW78906.1 - 0.044 13.3 0.1 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain KAP_NTPase PF07693.9 EIW78906.1 - 0.056 12.4 0.3 2.3 7.1 0.0 2.2 1 1 0 2 2 2 0 KAP family P-loop domain Sigma54_activ_2 PF14532.1 EIW78906.1 - 0.06 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 EIW78906.1 - 0.063 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter T2SE PF00437.15 EIW78906.1 - 0.068 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein UPF0079 PF02367.12 EIW78906.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_17 PF13207.1 EIW78906.1 - 0.11 13.2 0.0 0.27 12.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EIW78906.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.8 EIW78906.1 - 0.13 10.9 0.0 0.25 10.0 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus DUF258 PF03193.11 EIW78906.1 - 0.17 11.1 0.0 0.31 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MbtH PF03621.8 EIW78907.1 - 0.013 14.8 1.4 0.017 14.5 1.0 1.2 1 0 0 1 1 1 0 MbtH-like protein GST_N_3 PF13417.1 EIW78908.1 - 7.3e-15 54.9 0.1 2e-14 53.5 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW78908.1 - 2.6e-10 40.1 0.1 5.1e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW78908.1 - 1.6e-06 27.8 0.5 3.9e-06 26.6 0.4 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW78908.1 - 4.9e-05 23.2 0.1 0.00014 21.7 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW78908.1 - 0.00025 21.4 0.0 0.00048 20.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW78908.1 - 0.056 13.6 0.0 0.2 11.8 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain zf-met PF12874.2 EIW78911.1 - 0.00056 20.0 0.1 0.096 12.9 0.0 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EIW78911.1 - 0.1 12.9 1.5 0.19 12.1 0.0 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EIW78911.1 - 0.12 12.5 0.1 0.95 9.6 0.0 2.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding GST_N_3 PF13417.1 EIW78914.1 - 9e-15 54.6 0.1 2.5e-14 53.2 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW78914.1 - 3.1e-10 39.9 0.1 5.9e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW78914.1 - 5.3e-06 26.2 0.2 1.3e-05 25.0 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW78914.1 - 4.4e-05 23.8 0.2 8.2e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW78914.1 - 7.9e-05 22.5 0.1 0.00031 20.6 0.0 1.9 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW78914.1 - 0.069 13.3 0.0 0.24 11.6 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain O-FucT PF10250.4 EIW78916.1 - 1.1e-08 34.6 0.0 1.6e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase MFS_1 PF07690.11 EIW78917.1 - 3.4e-19 68.7 54.9 2.1e-14 53.0 23.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM171 PF15471.1 EIW78917.1 - 0.065 12.0 0.2 0.12 11.1 0.1 1.3 1 0 0 1 1 1 0 Transmembrane protein family 171 Scs3p PF10261.4 EIW78917.1 - 0.58 9.1 7.3 4 6.4 2.0 2.4 2 0 0 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM FUSC-like PF12805.2 EIW78917.1 - 1.9 7.3 3.7 0.51 9.2 0.1 1.8 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS Methyltransf_23 PF13489.1 EIW78919.1 - 7.9e-12 45.1 0.0 2e-11 43.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW78919.1 - 4.6e-10 39.2 0.0 9.6e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW78919.1 - 1.6e-09 38.1 0.0 3.1e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW78919.1 - 4.9e-09 35.6 0.0 1.4e-08 34.1 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EIW78919.1 - 1.4e-08 34.9 0.0 4.1e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW78919.1 - 1.9e-07 31.6 0.0 7.4e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW78919.1 - 2.9e-07 30.8 0.0 6.7e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW78919.1 - 0.00047 20.1 0.0 0.0027 17.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EIW78919.1 - 0.0048 16.0 0.1 0.046 12.7 0.0 2.4 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.10 EIW78919.1 - 0.0067 16.0 0.1 0.012 15.2 0.1 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase PCMT PF01135.14 EIW78919.1 - 0.026 14.0 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EIW78919.1 - 0.042 12.8 0.0 0.21 10.6 0.0 2.0 2 0 0 2 2 2 0 Putative methyltransferase Imm42 PF15601.1 EIW78919.1 - 0.096 12.1 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 42 MFS_1 PF07690.11 EIW78920.1 - 0.0085 14.8 7.8 0.014 14.1 5.4 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW78920.1 - 0.011 14.2 7.5 0.013 14.0 5.2 1.0 1 0 0 1 1 1 0 Sugar (and other) transporter DUF3397 PF11877.3 EIW78920.1 - 0.016 15.1 2.5 0.024 14.6 1.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3397) FUSC-like PF12805.2 EIW78920.1 - 0.051 12.4 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS CoA_binding_3 PF13727.1 EIW78920.1 - 6.8 6.4 6.1 1.4 8.7 0.7 1.9 1 1 1 2 2 2 0 CoA-binding domain Spt4 PF06093.8 EIW78921.1 - 0.051 13.4 0.1 0.14 12.0 0.0 1.8 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger Mit_proteolip PF08039.6 EIW78923.1 - 8.7e-05 22.4 0.8 0.00026 20.8 0.5 1.8 1 0 0 1 1 1 1 Mitochondrial proteolipid DUF1435 PF07256.7 EIW78923.1 - 0.053 13.5 2.8 2.4 8.1 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1435) MFS_1 PF07690.11 EIW78924.1 - 2.1e-09 36.5 33.5 1.5e-07 30.4 11.4 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF3328 PF11807.3 EIW78925.1 - 7.2e-19 68.3 4.7 1.3e-18 67.5 3.3 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) AMP-binding PF00501.23 EIW78927.1 - 1.2e-25 89.8 0.3 2.7e-25 88.6 0.2 1.5 1 1 0 1 1 1 1 AMP-binding enzyme APS_kinase PF01583.15 EIW78929.1 - 0.029 14.0 0.0 0.044 13.4 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase WD40 PF00400.27 EIW78930.1 - 1.3e-86 281.6 26.6 7.6e-12 44.6 1.3 8.5 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 EIW78930.1 - 1.3e-06 26.9 5.6 0.037 12.1 0.0 4.3 4 1 0 4 4 4 3 Nucleoporin Nup120/160 NLE PF08154.7 EIW78930.1 - 2e-06 27.7 0.0 3.1e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 NLE (NUC135) domain Nbas_N PF15492.1 EIW78930.1 - 0.00073 18.7 0.2 9.1 5.2 0.0 4.1 5 0 0 5 5 5 1 Neuroblastoma-amplified sequence, N terminal TFIIIC_delta PF12657.2 EIW78930.1 - 0.13 11.9 1.1 46 3.6 0.0 3.7 2 1 0 3 3 3 0 Transcription factor IIIC subunit delta N-term RhoGEF PF00621.15 EIW78931.1 - 5.5e-36 124.1 0.0 7.6e-36 123.6 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.16 EIW78931.1 - 3.1e-17 62.2 8.0 5.1e-17 61.5 5.5 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 EIW78931.1 - 0.32 10.8 5.4 0.69 9.8 3.8 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger zf-SNAP50_C PF12251.3 EIW78931.1 - 3.2 7.0 3.5 4.5 6.6 1.8 1.5 2 0 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal Aldo_ket_red PF00248.16 EIW78932.1 - 4.7e-43 147.0 0.0 5.7e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family P3A PF08727.6 EIW78932.1 - 0.088 12.1 0.4 1.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Poliovirus 3A protein like adh_short PF00106.20 EIW78933.1 - 1.3e-12 48.0 0.7 2.1e-12 47.2 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW78933.1 - 3e-09 36.9 0.0 5.3e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW78933.1 - 0.0064 16.1 0.1 0.013 15.1 0.1 1.5 1 1 0 1 1 1 1 KR domain MFS_1 PF07690.11 EIW78934.1 - 1.9e-32 112.3 39.6 1.9e-32 112.3 27.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW78934.1 - 3.2e-10 39.1 31.8 7.5e-09 34.6 10.9 2.7 2 1 0 3 3 3 2 Sugar (and other) transporter DUF4405 PF14358.1 EIW78935.1 - 0.0094 16.0 0.2 0.024 14.7 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4405) DUF3328 PF11807.3 EIW78936.1 - 6.4e-22 78.3 2.4 1.5e-21 77.1 1.6 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) NACHT PF05729.7 EIW78941.1 - 4e-08 33.0 0.0 1.8e-07 30.9 0.0 2.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW78941.1 - 1.2e-06 28.6 2.6 2.7e-06 27.4 0.1 2.7 3 2 0 3 3 3 1 AAA ATPase domain Arch_ATPase PF01637.13 EIW78941.1 - 2.3e-06 27.4 0.0 4.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EIW78941.1 - 0.0002 21.5 0.0 0.00059 19.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIW78941.1 - 0.00072 18.6 0.0 0.012 14.7 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin APS_kinase PF01583.15 EIW78941.1 - 0.0031 17.2 0.0 0.0065 16.1 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.17 EIW78941.1 - 0.004 17.2 0.0 0.016 15.3 0.0 2.0 2 0 0 2 2 2 1 RNA helicase PRK PF00485.13 EIW78941.1 - 0.044 13.3 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA PF00004.24 EIW78941.1 - 0.049 13.8 0.0 0.2 11.8 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EIW78941.1 - 0.052 12.4 0.0 0.14 11.0 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_18 PF13238.1 EIW78941.1 - 0.07 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIW78941.1 - 0.074 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EIW78941.1 - 0.076 13.8 0.0 0.22 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF3368 PF11848.3 EIW78941.1 - 0.092 12.3 0.0 0.63 9.6 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) Sigma54_activ_2 PF14532.1 EIW78941.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 EIW78941.1 - 0.14 11.5 0.0 0.31 10.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 EIW78941.1 - 0.21 11.8 0.0 0.45 10.8 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RabGAP-TBC PF00566.13 EIW78942.1 - 7.7e-48 162.7 0.0 1.4e-47 161.9 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_7 PF13499.1 EIW78942.1 - 1.3e-06 28.3 1.3 7.4e-06 26.0 0.6 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EIW78942.1 - 1.1e-05 24.9 0.9 0.0028 17.3 0.1 3.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.27 EIW78942.1 - 0.00028 19.9 0.1 0.0042 16.2 0.0 2.7 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EIW78942.1 - 0.0016 18.0 0.2 0.52 9.9 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair GRAM PF02893.15 EIW78942.1 - 0.0095 15.4 0.0 0.024 14.1 0.0 1.7 1 0 0 1 1 1 1 GRAM domain SPARC_Ca_bdg PF10591.4 EIW78942.1 - 0.17 11.9 0.1 0.5 10.4 0.0 1.8 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Aldo_ket_red PF00248.16 EIW78943.1 - 1.7e-48 164.8 0.0 2e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2306 PF10067.4 EIW78944.1 - 4.8 7.3 7.7 0.91 9.6 0.4 2.7 2 1 0 2 2 2 0 Predicted membrane protein (DUF2306) MMR_HSR1 PF01926.18 EIW78945.1 - 4.6e-11 42.6 0.0 6.8e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EIW78945.1 - 0.00022 21.1 0.0 0.11 12.3 0.0 2.2 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.11 EIW78945.1 - 0.054 12.5 0.0 0.13 11.3 0.0 1.5 1 1 0 1 1 1 0 AIG1 family Methyltransf_20 PF12147.3 EIW78948.1 - 0.16 10.8 0.0 0.19 10.5 0.0 1.0 1 0 0 1 1 1 0 Putative methyltransferase DNA_binding_1 PF01035.15 EIW78949.1 - 4.1e-10 39.2 0.1 1.7e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain HTH_20 PF12840.2 EIW78949.1 - 0.05 13.4 0.0 0.093 12.5 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain WD40 PF00400.27 EIW78951.1 - 4.8e-64 210.1 18.9 2.9e-10 39.6 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EIW78951.1 - 4.6e-10 39.5 0.8 0.00045 19.9 0.0 4.1 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIW78951.1 - 1.1e-06 27.0 8.7 0.015 13.5 0.2 4.7 1 1 3 4 4 4 3 Nucleoporin Nup120/160 CDtoxinA PF03498.9 EIW78951.1 - 6.8e-05 22.2 1.5 0.006 15.9 0.1 2.8 1 1 0 2 2 2 1 Cytolethal distending toxin A/C family Pectate_lyase22 PF14583.1 EIW78951.1 - 0.035 12.5 0.0 0.15 10.4 0.0 1.8 1 1 0 2 2 2 0 Oligogalacturonate lyase Cytochrom_D1 PF02239.11 EIW78951.1 - 0.047 11.9 0.1 0.27 9.4 0.1 2.2 2 1 0 2 2 2 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 EIW78951.1 - 0.057 12.1 1.4 0.72 8.5 0.1 2.9 1 1 2 3 3 3 0 Nup133 N terminal like Coatomer_WDAD PF04053.9 EIW78951.1 - 0.18 10.5 0.1 0.78 8.4 0.0 2.0 2 1 0 2 2 2 0 Coatomer WD associated region BPD_transp_2 PF02653.11 EIW78952.1 - 0.56 9.1 15.4 0.77 8.6 10.0 1.7 1 1 0 1 1 1 0 Branched-chain amino acid transport system / permease component NACHT PF05729.7 EIW78953.1 - 1.5e-05 24.7 0.2 0.0004 20.0 0.1 2.6 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW78953.1 - 0.00012 22.1 2.4 0.00063 19.7 0.3 3.1 4 1 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 EIW78953.1 - 0.00028 21.0 1.0 0.0061 16.6 0.1 3.1 2 1 0 2 2 2 1 AAA domain AAA PF00004.24 EIW78953.1 - 0.0012 19.0 0.2 0.026 14.6 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EIW78953.1 - 0.0027 17.8 0.0 0.034 14.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Arch_ATPase PF01637.13 EIW78953.1 - 0.004 16.8 0.2 2.9 7.5 0.0 2.5 3 0 0 3 3 3 2 Archaeal ATPase APS_kinase PF01583.15 EIW78953.1 - 0.0075 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase DUF2075 PF09848.4 EIW78953.1 - 0.0081 15.1 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 EIW78953.1 - 0.04 12.8 0.0 0.11 11.3 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein Zeta_toxin PF06414.7 EIW78953.1 - 0.045 12.8 0.0 0.088 11.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EIW78953.1 - 0.058 13.7 0.0 1.7 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EIW78953.1 - 0.061 13.1 0.0 0.21 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EIW78953.1 - 0.068 12.5 0.0 0.7 9.2 0.0 2.7 1 1 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 EIW78953.1 - 0.16 11.5 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EIW78954.1 - 3e-08 33.8 0.1 4.5e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EIW78954.1 - 1.4e-06 28.1 0.0 1.7e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EIW78954.1 - 8.5e-06 25.9 0.0 1.8e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EIW78954.1 - 0.0003 20.5 0.0 0.00048 19.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.7 EIW78954.1 - 0.00044 19.3 0.0 0.00063 18.8 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin Sigma54_activ_2 PF14532.1 EIW78954.1 - 0.001 19.1 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 Sigma-54 interaction domain DUF815 PF05673.8 EIW78954.1 - 0.0014 17.6 0.0 0.0019 17.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 EIW78954.1 - 0.0025 17.3 0.0 0.0044 16.5 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain APS_kinase PF01583.15 EIW78954.1 - 0.0036 16.9 0.0 0.0055 16.3 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_29 PF13555.1 EIW78954.1 - 0.0038 16.7 0.0 0.006 16.0 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EIW78954.1 - 0.005 17.1 0.0 0.006 16.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter DUF2075 PF09848.4 EIW78954.1 - 0.0051 15.8 0.0 0.0057 15.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PRK PF00485.13 EIW78954.1 - 0.0051 16.3 0.0 0.0068 15.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family IstB_IS21 PF01695.12 EIW78954.1 - 0.0073 15.7 0.0 0.0091 15.4 0.0 1.2 1 0 0 1 1 1 1 IstB-like ATP binding protein PIF1 PF05970.9 EIW78954.1 - 0.0078 15.2 0.0 0.0093 14.9 0.0 1.1 1 0 0 1 1 1 1 PIF1-like helicase T2SE PF00437.15 EIW78954.1 - 0.021 13.7 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.11 EIW78954.1 - 0.024 13.8 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.1 EIW78954.1 - 0.028 14.2 0.0 0.068 13.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain CoaE PF01121.15 EIW78954.1 - 0.031 13.6 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Dephospho-CoA kinase NTPase_1 PF03266.10 EIW78954.1 - 0.038 13.7 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.1 EIW78954.1 - 0.047 13.9 0.0 0.068 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIW78954.1 - 0.048 12.8 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EIW78954.1 - 0.055 13.6 0.0 0.08 13.1 0.0 1.3 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 EIW78954.1 - 0.056 13.1 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 Part of AAA domain NB-ARC PF00931.17 EIW78954.1 - 0.06 12.1 0.0 0.073 11.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DAP3 PF10236.4 EIW78954.1 - 0.068 12.0 0.0 0.096 11.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 KaiC PF06745.8 EIW78954.1 - 0.072 12.2 0.0 0.094 11.8 0.0 1.2 1 0 0 1 1 1 0 KaiC KTI12 PF08433.5 EIW78954.1 - 0.085 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Miro PF08477.8 EIW78954.1 - 0.1 13.0 0.0 0.83 10.1 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein DUF2791 PF10923.3 EIW78954.1 - 0.13 10.8 0.0 0.16 10.5 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) AAA_5 PF07728.9 EIW78954.1 - 0.14 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CobU PF02283.11 EIW78954.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Lactonase PF10282.4 EIW78955.1 - 0.14 11.1 0.1 1.6 7.7 0.0 2.1 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller O-FucT PF10250.4 EIW78956.1 - 1e-06 28.1 0.0 1.4e-06 27.6 0.0 1.1 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Acetyltransf_10 PF13673.1 EIW78957.1 - 8e-08 32.4 0.0 1.7e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW78957.1 - 4.4e-06 26.6 0.0 9.3e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIW78957.1 - 0.00061 19.8 0.0 0.0011 19.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain F-box PF00646.28 EIW78958.1 - 0.012 15.3 0.0 0.034 13.8 0.0 1.8 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 EIW78958.1 - 0.086 12.5 0.0 0.49 10.1 0.0 2.2 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 EIW78960.1 - 0.003 17.1 0.0 0.0059 16.2 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW78960.1 - 0.012 15.3 0.2 0.031 13.9 0.1 1.7 1 0 0 1 1 1 0 F-box-like RicinB_lectin_2 PF14200.1 EIW78961.1 - 0.0016 18.7 0.0 0.035 14.4 0.0 2.5 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Glyco_hydro_18 PF00704.23 EIW78962.1 - 3.2e-11 43.2 1.3 4e-11 42.9 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 YjbE PF11106.3 EIW78962.1 - 0.041 13.8 2.4 0.041 13.8 1.7 2.8 3 0 0 3 3 3 0 Exopolysaccharide production protein YjbE F-box PF00646.28 EIW78963.1 - 0.024 14.2 2.5 0.046 13.3 1.7 1.5 1 0 0 1 1 1 0 F-box domain Glyco_hydro_18 PF00704.23 EIW78965.1 - 4.6e-12 46.0 2.8 5.8e-12 45.7 2.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 F-box PF00646.28 EIW78966.1 - 0.11 12.1 0.9 0.49 10.1 0.7 1.9 2 0 0 2 2 2 0 F-box domain zf-HC5HC2H_2 PF13832.1 EIW78967.1 - 0.032 14.2 1.3 0.032 14.2 0.9 1.9 2 0 0 2 2 2 0 PHD-zinc-finger like domain zf-Di19 PF05605.7 EIW78967.1 - 1.1 9.4 4.4 0.35 11.0 0.3 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding GATA PF00320.22 EIW78969.1 - 9e-14 50.5 2.6 1.7e-13 49.6 1.8 1.5 1 0 0 1 1 1 1 GATA zinc finger Spt20 PF12090.3 EIW78970.1 - 3.1e-30 104.8 0.0 3.1e-30 104.8 0.0 6.3 3 2 0 3 3 3 1 Spt20 family DUF383 PF04063.9 EIW78971.1 - 1.8e-53 180.9 0.0 2.9e-53 180.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EIW78971.1 - 2.7e-14 52.4 0.5 5.5e-14 51.4 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Proteasom_PSMB PF10508.4 EIW78971.1 - 0.084 11.1 0.1 8.5 4.5 0.0 2.5 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit MFS_1 PF07690.11 EIW78972.1 - 3.7e-32 111.4 48.6 1.3e-31 109.6 28.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW78972.1 - 5.3e-08 31.8 39.9 6e-08 31.7 22.1 3.0 1 1 1 2 2 2 2 Sugar (and other) transporter RTC4 PF14474.1 EIW78974.1 - 1.7e-20 73.1 0.0 1.9e-20 73.0 0.0 1.0 1 0 0 1 1 1 1 RTC4-like domain ANTAR PF03861.9 EIW78974.1 - 0.0056 16.2 0.0 0.0085 15.6 0.0 1.2 1 0 0 1 1 1 1 ANTAR domain MIP-T3 PF10243.4 EIW78975.1 - 0.11 10.8 42.1 0.16 10.3 29.2 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Imm15 PF15590.1 EIW78976.1 - 0.033 13.2 0.0 0.44 9.6 0.0 2.7 2 1 1 3 3 3 0 Immunity protein 15 Chromo PF00385.19 EIW78977.1 - 3.4e-09 36.2 0.5 6.2e-09 35.3 0.1 1.7 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain AvrE PF11725.3 EIW78977.1 - 0.029 11.4 4.8 0.031 11.3 3.3 1.0 1 0 0 1 1 1 0 Pathogenicity factor Microtub_bind PF13931.1 EIW78977.1 - 0.47 10.5 5.1 0.27 11.3 0.9 2.0 1 1 1 2 2 2 0 Kinesin-associated microtubule-binding MRI PF15325.1 EIW78977.1 - 2.6 9.0 14.4 0.63 11.0 4.8 2.4 1 1 1 2 2 2 0 Modulator of retrovirus infection RRM_1 PF00076.17 EIW78978.1 - 3.7e-14 52.1 0.0 5.8e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW78978.1 - 6.6e-12 45.2 0.0 1.2e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW78978.1 - 1.5e-06 27.9 0.0 2.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HMA PF00403.21 EIW78978.1 - 0.069 13.3 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Heavy-metal-associated domain RRM_3 PF08777.6 EIW78978.1 - 0.087 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA binding motif zf-MYND PF01753.13 EIW78979.1 - 3.1e-06 26.9 15.5 4.8e-06 26.3 10.7 1.3 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EIW78979.1 - 1.2 9.0 8.5 2.6 7.9 5.9 1.5 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DNA_Packaging_2 PF11123.3 EIW78981.1 - 0.018 14.8 0.2 0.061 13.2 0.0 1.9 2 0 0 2 2 2 0 DNA packaging protein Dimer_Tnp_hAT PF05699.9 EIW78982.1 - 1.8e-10 40.2 0.1 1.9e-10 40.2 0.1 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ECR1_N PF14382.1 EIW78983.1 - 3.7e-15 54.9 0.1 6.7e-15 54.0 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EIW78983.1 - 0.00097 19.0 0.0 0.039 13.9 0.0 2.5 1 1 0 1 1 1 1 Exosome component EXOSC1/CSL4 Nucleoplasmin PF03066.10 EIW78984.1 - 0.5 9.8 7.8 1.1 8.8 5.4 1.6 1 0 0 1 1 1 0 Nucleoplasmin BUD22 PF09073.5 EIW78984.1 - 0.53 9.3 5.4 0.65 9.0 3.7 1.2 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EIW78984.1 - 1.6 6.5 8.6 1.7 6.4 5.9 1.1 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.7 EIW78984.1 - 5.2 6.2 10.2 6.9 5.8 7.1 1.2 1 0 0 1 1 1 0 NOA36 protein RINGv PF12906.2 EIW78985.1 - 9e-16 57.6 6.4 1.5e-15 56.9 4.4 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EIW78985.1 - 0.17 11.7 7.6 0.32 10.8 5.2 1.5 1 0 0 1 1 1 0 Ring finger domain zf-Apc11 PF12861.2 EIW78985.1 - 0.36 10.7 3.4 0.69 9.7 2.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.6 EIW78985.1 - 3.4 7.7 6.3 5.7 7.0 4.4 1.3 1 0 0 1 1 1 0 RING-like domain MFS_1 PF07690.11 EIW78986.1 - 2.2e-34 118.7 44.5 5.2e-33 114.2 27.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW78986.1 - 1.3e-10 40.5 11.5 1.3e-10 40.5 8.0 3.3 3 1 0 3 3 3 2 Sugar (and other) transporter Glyco_hydro_18 PF00704.23 EIW78988.1 - 1.6e-10 41.0 1.9 1.9e-10 40.7 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 RicinB_lectin_2 PF14200.1 EIW78989.1 - 1.8e-08 34.7 0.0 0.0063 16.8 0.0 2.6 2 1 0 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EIW78989.1 - 0.00065 19.7 0.1 0.01 15.8 0.0 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain GTP_EFTU PF00009.22 EIW78991.1 - 2.6e-62 209.5 0.3 3.9e-62 209.0 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EIW78991.1 - 3.4e-38 129.8 0.0 1.2e-37 128.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EIW78991.1 - 1.4e-21 76.1 0.0 3.1e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EIW78991.1 - 1.8e-13 50.1 0.0 5.7e-13 48.5 0.0 1.8 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EIW78991.1 - 7.5e-12 45.2 0.1 5.1e-11 42.5 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIW78991.1 - 2.2e-05 24.3 0.2 4.9e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EIW78991.1 - 0.1 12.1 0.2 0.37 10.2 0.1 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation F-box PF00646.28 EIW78992.1 - 4.1e-05 23.0 0.1 8.7e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW78992.1 - 0.00028 20.5 0.4 0.00082 19.0 0.2 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIW78993.1 - 1.5e-05 24.5 0.0 3.4e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain APS_kinase PF01583.15 EIW78996.1 - 0.00021 20.9 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.1 EIW78996.1 - 0.00036 21.3 0.0 0.00053 20.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EIW78996.1 - 0.00061 19.9 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.1 EIW78996.1 - 0.0011 18.9 0.0 0.0013 18.7 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EIW78996.1 - 0.0014 17.8 0.0 0.0016 17.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EIW78996.1 - 0.0021 18.3 0.0 0.0027 18.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIW78996.1 - 0.0052 17.0 0.1 0.007 16.6 0.1 1.2 1 0 0 1 1 1 1 ABC transporter NACHT PF05729.7 EIW78996.1 - 0.0059 16.2 0.2 0.0077 15.9 0.1 1.2 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EIW78996.1 - 0.0064 16.6 0.0 0.0088 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain PhoH PF02562.11 EIW78996.1 - 0.0079 15.4 0.1 0.0097 15.1 0.1 1.1 1 0 0 1 1 1 1 PhoH-like protein CbiA PF01656.18 EIW78996.1 - 0.0079 15.6 0.1 0.0095 15.3 0.1 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_29 PF13555.1 EIW78996.1 - 0.008 15.6 0.1 0.012 15.1 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_30 PF13604.1 EIW78996.1 - 0.0081 15.7 0.2 0.01 15.4 0.1 1.1 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EIW78996.1 - 0.0094 15.3 0.1 0.011 15.1 0.1 1.1 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EIW78996.1 - 0.0097 15.3 0.1 0.011 15.1 0.0 1.1 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EIW78996.1 - 0.011 15.4 0.0 0.015 15.0 0.0 1.3 1 1 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 EIW78996.1 - 0.012 15.3 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EIW78996.1 - 0.012 15.6 0.1 0.018 14.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EIW78996.1 - 0.014 15.1 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EIW78996.1 - 0.03 13.1 0.0 0.037 12.8 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 EIW78996.1 - 0.033 13.0 0.0 0.038 12.8 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_14 PF13173.1 EIW78996.1 - 0.033 14.0 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EIW78996.1 - 0.036 13.0 0.0 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SE PF00437.15 EIW78996.1 - 0.052 12.4 0.0 0.056 12.3 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 EIW78996.1 - 0.053 13.3 0.1 0.097 12.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EIW78996.1 - 0.063 12.7 0.0 0.083 12.3 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA PF00004.24 EIW78996.1 - 0.076 13.2 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATP_bind_1 PF03029.12 EIW78996.1 - 0.084 12.3 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein PRK PF00485.13 EIW78996.1 - 0.11 12.0 0.1 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family TIP49 PF06068.8 EIW78996.1 - 0.12 11.1 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus DUF815 PF05673.8 EIW78996.1 - 0.14 11.0 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MFS_1 PF07690.11 EIW78998.1 - 1.3e-30 106.2 41.8 1.7e-29 102.6 22.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW78998.1 - 5.6e-08 31.7 30.2 1.3e-07 30.5 20.9 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter HD_3 PF13023.1 EIW78999.1 - 1e-41 142.4 0.7 1.3e-41 142.1 0.5 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EIW78999.1 - 4.2e-07 30.0 0.9 7.6e-07 29.1 0.6 1.5 1 0 0 1 1 1 1 HD domain DUF1025 PF06262.6 EIW78999.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase Sds3 PF08598.6 EIW79000.1 - 3.8e-07 29.8 0.1 1e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 Sds3-like NACHT PF05729.7 EIW79001.1 - 1.2e-09 38.0 0.0 2.5e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EIW79001.1 - 4e-05 23.7 0.0 0.0053 16.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIW79001.1 - 0.00074 19.5 0.8 0.0034 17.3 0.1 2.1 2 0 0 2 2 2 1 AAA ATPase domain APS_kinase PF01583.15 EIW79001.1 - 0.0057 16.3 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase ATP-synt_F6 PF05511.6 EIW79001.1 - 0.0081 16.0 0.0 0.021 14.7 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ATP synthase coupling factor 6 RNA_helicase PF00910.17 EIW79001.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 EIW79001.1 - 0.023 14.4 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 EIW79001.1 - 0.043 14.6 0.0 0.13 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIW79001.1 - 0.16 11.0 0.0 0.29 10.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.22 EIW79001.1 - 0.19 12.0 0.0 0.34 11.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter F-box PF00646.28 EIW79002.1 - 0.00013 21.4 0.4 0.00027 20.4 0.3 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW79002.1 - 0.012 15.2 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 F-box-like zf-RING-like PF08746.6 EIW79003.1 - 0.16 12.0 0.5 12 5.9 0.2 2.4 2 0 0 2 2 2 0 RING-like domain RNA_helicase PF00910.17 EIW79004.1 - 0.00045 20.3 0.0 0.00068 19.7 0.0 1.3 1 0 0 1 1 1 1 RNA helicase APS_kinase PF01583.15 EIW79004.1 - 0.0029 17.2 0.0 0.0039 16.8 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase PhoH PF02562.11 EIW79004.1 - 0.0038 16.4 0.0 0.0046 16.2 0.0 1.1 1 0 0 1 1 1 1 PhoH-like protein AAA_16 PF13191.1 EIW79004.1 - 0.0044 17.0 0.1 0.0053 16.7 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EIW79004.1 - 0.0049 16.5 0.0 0.0073 15.9 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Parvo_NS1 PF01057.12 EIW79004.1 - 0.017 13.9 0.0 0.018 13.9 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.1 EIW79004.1 - 0.022 15.5 0.0 0.039 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EIW79004.1 - 0.024 14.0 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIW79004.1 - 0.025 13.7 0.0 0.028 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIW79004.1 - 0.026 14.6 0.0 0.054 13.6 0.0 1.5 1 1 1 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EIW79004.1 - 0.029 13.7 0.0 0.033 13.6 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.1 EIW79004.1 - 0.034 13.7 0.0 0.046 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EIW79004.1 - 0.043 12.7 0.0 0.046 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA PF00004.24 EIW79004.1 - 0.044 13.9 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EIW79004.1 - 0.055 12.3 0.0 0.068 12.0 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.22 EIW79004.1 - 0.062 13.6 0.0 0.1 12.9 0.0 1.4 1 1 0 1 1 1 0 ABC transporter DUF2075 PF09848.4 EIW79004.1 - 0.085 11.8 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.9 EIW79004.1 - 0.1 11.5 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase AAA_5 PF07728.9 EIW79004.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DLH PF01738.13 EIW79005.1 - 1e-26 93.6 0.0 1.1e-26 93.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EIW79005.1 - 1.3e-07 31.4 0.0 2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW79005.1 - 1.2e-05 25.3 0.0 0.11 12.3 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EIW79005.1 - 0.0011 17.9 0.0 0.0014 17.5 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EIW79005.1 - 0.0017 17.2 0.0 0.0023 16.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase DLH PF01738.13 EIW79006.1 - 1.7e-22 79.8 0.0 2e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EIW79006.1 - 9e-07 28.7 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW79006.1 - 0.00034 20.5 0.0 0.0013 18.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW79006.1 - 0.05 13.1 0.1 0.074 12.5 0.0 1.4 1 1 0 1 1 1 0 alpha/beta hydrolase fold Arch_ATPase PF01637.13 EIW79007.1 - 0.00074 19.2 0.0 0.00087 19.0 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EIW79007.1 - 0.00093 18.8 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 EIW79007.1 - 0.0026 17.8 0.0 0.0043 17.1 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.1 EIW79007.1 - 0.0027 17.7 0.1 0.0036 17.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.15 EIW79007.1 - 0.0033 17.0 0.0 0.0049 16.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.7 EIW79007.1 - 0.015 14.3 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EIW79007.1 - 0.017 15.9 0.0 0.022 15.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EIW79007.1 - 0.03 14.5 0.0 0.043 14.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EIW79007.1 - 0.061 13.0 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Parvo_NS1 PF01057.12 EIW79007.1 - 0.063 12.1 0.0 0.075 11.8 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2075 PF09848.4 EIW79007.1 - 0.071 12.0 0.0 0.084 11.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.1 EIW79007.1 - 0.073 12.6 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.12 EIW79007.1 - 0.076 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.17 EIW79007.1 - 0.087 11.6 0.0 0.16 10.8 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain APOC4 PF15119.1 EIW79007.1 - 0.1 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein C4 AAA_18 PF13238.1 EIW79007.1 - 0.12 12.7 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EIW79007.1 - 0.13 11.6 0.1 0.23 10.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 EIW79007.1 - 0.15 11.2 0.0 0.2 10.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 O-FucT PF10250.4 EIW79008.1 - 8.4e-08 31.7 0.0 1.7e-07 30.6 0.0 1.4 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase DLH PF01738.13 EIW79010.1 - 9e-21 74.1 0.0 1e-20 73.9 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EIW79010.1 - 3.2e-07 30.2 0.0 4.3e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW79010.1 - 0.0021 17.9 0.0 0.0036 17.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EIW79011.1 - 4.7e-26 91.4 0.0 5.3e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EIW79011.1 - 3.6e-09 36.5 0.0 5.8e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW79011.1 - 3.2e-06 27.1 0.0 0.0011 18.9 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family OpuAC PF04069.7 EIW79011.1 - 0.0041 16.5 0.0 0.021 14.1 0.0 1.9 2 0 0 2 2 2 1 Substrate binding domain of ABC-type glycine betaine transport system DUF3530 PF12048.3 EIW79011.1 - 0.084 11.8 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) AICARFT_IMPCHas PF01808.13 EIW79012.1 - 2.2e-113 378.5 0.0 2.8e-113 378.1 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EIW79012.1 - 3.4e-23 81.3 0.0 6.1e-23 80.5 0.0 1.4 1 0 0 1 1 1 1 MGS-like domain Smr PF01713.16 EIW79013.1 - 9.2e-12 44.9 0.2 7.5e-11 42.0 0.0 2.1 2 0 0 2 2 2 1 Smr domain DUF1771 PF08590.5 EIW79013.1 - 0.015 15.2 1.7 0.027 14.4 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1771) Retinal PF15449.1 EIW79013.1 - 0.9 7.1 4.2 1.1 6.8 2.9 1.1 1 0 0 1 1 1 0 Retinal protein DUF2015 PF09435.5 EIW79014.1 - 5.3e-36 123.2 0.0 5.8e-36 123.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) NACHT PF05729.7 EIW79015.1 - 5.1e-10 39.2 0.0 9e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW79015.1 - 4.1e-06 26.9 0.1 9.3e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain Kelch_4 PF13418.1 EIW79015.1 - 0.00028 20.5 1.0 5.1 6.9 0.0 4.0 3 0 0 3 3 3 2 Galactose oxidase, central domain WD40 PF00400.27 EIW79015.1 - 0.00051 19.8 6.9 0.0042 16.9 0.1 5.2 6 0 0 6 6 5 1 WD domain, G-beta repeat Arch_ATPase PF01637.13 EIW79015.1 - 0.00069 19.3 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase Nbas_N PF15492.1 EIW79015.1 - 0.013 14.5 0.1 0.43 9.6 0.0 2.6 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal RNA_helicase PF00910.17 EIW79015.1 - 0.032 14.4 0.0 0.071 13.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.15 EIW79015.1 - 0.058 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_22 PF13401.1 EIW79015.1 - 0.079 13.1 0.0 0.23 11.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain AMP_N PF05195.11 EIW79015.1 - 0.081 12.3 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain ABC_tran PF00005.22 EIW79015.1 - 0.28 11.4 0.0 0.51 10.6 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Arginosuc_synth PF00764.14 EIW79017.1 - 2e-153 511.0 0.0 2.3e-153 510.8 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.8 EIW79017.1 - 0.0019 17.5 0.0 0.0031 16.8 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 EIW79017.1 - 0.016 14.6 0.0 0.025 14.1 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase tRNA_Me_trans PF03054.11 EIW79017.1 - 0.11 11.0 0.0 0.39 9.2 0.0 1.7 1 1 1 2 2 2 0 tRNA methyl transferase zf-C3HC4_2 PF13923.1 EIW79018.1 - 2e-09 37.3 1.6 4.3e-09 36.2 1.1 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW79018.1 - 7.3e-09 35.3 7.2 1.3e-08 34.5 5.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EIW79018.1 - 2.7e-07 30.3 2.5 2.7e-07 30.3 1.7 1.8 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EIW79018.1 - 3.8e-07 29.6 5.1 6e-07 29.0 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW79018.1 - 2.4e-06 27.0 3.9 4.2e-06 26.3 2.3 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIW79018.1 - 2.8e-06 26.9 0.8 7.4e-06 25.5 0.6 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EIW79018.1 - 1.2e-05 24.9 5.6 2.5e-05 23.9 3.8 1.6 1 1 0 1 1 1 1 zinc-RING finger domain TFIIA PF03153.8 EIW79018.1 - 1.9e-05 24.7 10.3 2.6e-05 24.2 7.1 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RasGAP_C PF03836.10 EIW79018.1 - 0.00075 19.2 6.8 0.0014 18.2 4.7 1.4 1 0 0 1 1 1 1 RasGAP C-terminus zf-RING_6 PF14835.1 EIW79018.1 - 0.002 17.8 0.5 0.002 17.8 0.3 1.6 2 0 0 2 2 1 1 zf-RING of BARD1-type protein TMF_DNA_bd PF12329.3 EIW79018.1 - 0.0025 17.5 20.5 0.0068 16.1 14.2 1.7 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding Borrelia_P83 PF05262.6 EIW79018.1 - 0.0062 14.8 6.3 0.0081 14.4 4.4 1.2 1 0 0 1 1 1 1 Borrelia P83/100 protein Spc7 PF08317.6 EIW79018.1 - 0.014 14.1 12.4 0.021 13.4 8.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TBPIP PF07106.8 EIW79018.1 - 0.029 13.9 8.5 0.052 13.0 5.9 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Bacillus_HBL PF05791.6 EIW79018.1 - 0.054 12.8 3.5 0.089 12.1 2.4 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) YlqD PF11068.3 EIW79018.1 - 0.062 13.3 9.3 0.14 12.1 6.5 1.6 1 0 0 1 1 1 0 YlqD protein RTBV_P46 PF06216.6 EIW79018.1 - 0.1 11.3 3.7 0.15 10.8 2.5 1.1 1 0 0 1 1 1 0 Rice tungro bacilliform virus P46 protein DUF812 PF05667.6 EIW79018.1 - 0.2 10.1 14.8 0.3 9.5 10.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) IncA PF04156.9 EIW79018.1 - 0.31 10.6 18.0 0.56 9.7 12.5 1.3 1 0 0 1 1 1 0 IncA protein Seryl_tRNA_N PF02403.17 EIW79018.1 - 0.84 9.6 13.1 1.9 8.5 9.1 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain UPF0547 PF10571.4 EIW79018.1 - 0.85 9.3 7.9 0.14 11.9 1.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 APG6 PF04111.7 EIW79018.1 - 1.1 8.2 14.6 1.8 7.5 10.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF342 PF03961.8 EIW79018.1 - 1.1 7.5 7.2 1.5 7.1 5.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CHD5 PF04420.9 EIW79018.1 - 1.3 8.6 4.2 2.6 7.6 2.9 1.5 1 0 0 1 1 1 0 CHD5-like protein TMPIT PF07851.8 EIW79018.1 - 1.4 7.8 9.2 2.1 7.3 6.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.14 EIW79018.1 - 2.2 6.0 8.1 3.1 5.5 5.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FANCL_C PF11793.3 EIW79018.1 - 2.7 8.0 6.6 15 5.6 4.6 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain DUF4613 PF15390.1 EIW79018.1 - 2.9 5.9 7.0 3.9 5.5 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) zf-RING_4 PF14570.1 EIW79018.1 - 6.2 6.4 7.6 32 4.2 5.2 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2570 PF10828.3 EIW79018.1 - 8 6.1 9.3 15 5.2 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DLH PF01738.13 EIW79019.1 - 4.8e-27 94.6 0.0 5.5e-27 94.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EIW79019.1 - 7.4e-07 29.0 0.0 9.8e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW79019.1 - 0.00035 20.5 0.0 0.35 10.6 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family DLH PF01738.13 EIW79020.1 - 2.7e-21 75.8 0.0 3.1e-21 75.6 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 EIW79020.1 - 6.1e-06 26.2 0.0 0.00012 22.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW79020.1 - 1.1e-05 25.2 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family O-FucT PF10250.4 EIW79021.1 - 1.6e-06 27.4 0.0 5.3e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase O-FucT PF10250.4 EIW79022.1 - 6.1e-05 22.2 0.0 0.00012 21.3 0.0 1.4 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase NACHT PF05729.7 EIW79023.1 - 2e-10 40.5 0.0 1.5e-09 37.7 0.0 2.4 3 1 0 3 3 3 1 NACHT domain AAA_16 PF13191.1 EIW79023.1 - 0.0018 18.2 0.0 0.0059 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW79023.1 - 0.0077 16.3 0.0 0.041 14.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain WD40 PF00400.27 EIW79023.1 - 0.019 14.8 0.0 0.08 12.8 0.0 2.1 2 0 0 2 2 2 0 WD domain, G-beta repeat IstB_IS21 PF01695.12 EIW79023.1 - 0.072 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Nbas_N PF15492.1 EIW79023.1 - 0.078 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal APS_kinase PF01583.15 EIW79023.1 - 0.081 12.5 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.17 EIW79023.1 - 0.082 13.0 0.0 0.2 11.8 0.0 1.7 1 0 0 1 1 1 0 RNA helicase HEAT PF02985.17 EIW79023.1 - 0.096 12.8 0.0 0.31 11.2 0.0 1.9 1 0 0 1 1 1 0 HEAT repeat AAA_17 PF13207.1 EIW79023.1 - 0.11 13.2 0.2 0.36 11.6 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EIW79023.1 - 0.12 12.1 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 EIW79023.1 - 0.13 11.6 0.2 0.26 10.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain MFS_1 PF07690.11 EIW79024.1 - 4.6e-30 104.5 35.8 1.5e-29 102.8 22.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PTS_2-RNA PF01885.11 EIW79025.1 - 4.9e-59 198.7 0.1 6.4e-59 198.3 0.1 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family TINF2_N PF14973.1 EIW79025.1 - 0.074 13.1 0.2 0.11 12.6 0.2 1.2 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus DUF1318 PF07027.7 EIW79028.1 - 0.11 12.6 0.7 2 8.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1318) DEAD PF00270.24 EIW79032.1 - 2.3e-43 147.5 0.0 6.5e-43 146.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW79032.1 - 6.5e-27 93.2 0.1 1.2e-26 92.3 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW79032.1 - 0.0038 17.0 0.0 0.009 15.8 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EIW79032.1 - 0.15 11.0 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1318 PF07027.7 EIW79033.1 - 0.013 15.7 0.1 0.021 15.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1318) NACHT PF05729.7 EIW79034.1 - 1.6e-07 31.1 0.0 3.9e-07 29.8 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW79034.1 - 0.0066 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.15 EIW79034.1 - 0.016 14.8 0.1 0.042 13.5 0.0 1.7 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_22 PF13401.1 EIW79034.1 - 0.032 14.3 0.0 0.068 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EIW79034.1 - 0.05 14.4 0.1 0.13 13.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EIW79034.1 - 0.11 12.7 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 EIW79034.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_16 PF13191.1 EIW79035.1 - 8.8e-07 29.0 0.0 1e-06 28.8 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EIW79035.1 - 8.9e-06 25.5 0.0 9.4e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase APS_kinase PF01583.15 EIW79035.1 - 0.00038 20.1 0.0 0.00058 19.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase NACHT PF05729.7 EIW79035.1 - 0.0004 20.0 0.0 0.00046 19.8 0.0 1.3 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 EIW79035.1 - 0.0022 18.1 0.0 0.0032 17.6 0.0 1.3 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 EIW79035.1 - 0.0035 16.4 0.0 0.0055 15.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin ABC_tran PF00005.22 EIW79035.1 - 0.0047 17.2 0.0 0.01 16.1 0.0 1.4 1 1 1 2 2 2 1 ABC transporter AAA_22 PF13401.1 EIW79035.1 - 0.0093 16.1 0.0 0.011 15.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EIW79035.1 - 0.014 15.0 0.0 0.016 14.7 0.0 1.1 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family PIF1 PF05970.9 EIW79035.1 - 0.031 13.2 0.0 0.041 12.8 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase AAA_29 PF13555.1 EIW79035.1 - 0.035 13.6 0.0 0.058 12.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EIW79035.1 - 0.066 12.9 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EIW79035.1 - 0.076 12.2 0.0 0.098 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF1353 PF07087.6 EIW79035.1 - 0.079 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1353) AAA_18 PF13238.1 EIW79035.1 - 0.09 13.0 0.0 0.11 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_PrkA PF08298.6 EIW79035.1 - 0.1 11.2 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain DUF815 PF05673.8 EIW79035.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) MFS_1 PF07690.11 EIW79036.1 - 1.3e-20 73.4 32.0 2.8e-15 55.8 14.2 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily P5-ATPase PF12409.3 EIW79036.1 - 0.18 11.6 2.1 7.7 6.4 0.0 2.7 2 0 0 2 2 2 0 P5-type ATPase cation transporter DNA_pol_B PF00136.16 EIW79037.1 - 2.9e-113 379.1 0.0 4.5e-113 378.5 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EIW79037.1 - 8e-55 185.1 0.0 1.5e-54 184.2 0.0 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EIW79037.1 - 5.3e-25 87.9 0.0 9.1e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EIW79037.1 - 1.6e-16 59.8 8.3 5e-16 58.2 5.8 1.9 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal YL1 PF05764.8 EIW79037.1 - 0.79 9.2 12.1 1.8 8.1 8.4 1.5 1 0 0 1 1 1 0 YL1 nuclear protein zf-DNL PF05180.7 EIW79038.1 - 1.3e-27 95.2 0.4 1.8e-27 94.8 0.3 1.2 1 0 0 1 1 1 1 DNL zinc finger MFS_1 PF07690.11 EIW79039.1 - 6.9e-34 117.0 40.0 1.9e-33 115.6 22.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIW79039.1 - 1.9e-07 29.6 2.0 1.9e-07 29.6 1.4 1.4 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) EphA2_TM PF14575.1 EIW79039.1 - 9.8 6.6 6.3 1.4 9.3 0.1 2.8 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain F-box-like PF12937.2 EIW79041.1 - 0.072 12.8 0.1 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 F-box-like SIR2 PF02146.12 EIW79042.1 - 1.3e-55 187.8 0.0 2.4e-55 186.9 0.0 1.5 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EIW79042.1 - 2.7e-07 30.2 0.9 1e-05 25.1 0.3 2.3 1 1 0 2 2 2 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EIW79042.1 - 0.067 12.9 0.4 1.9 8.2 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Kei1 PF08552.6 EIW79043.1 - 8.5e-44 149.4 4.2 1.1e-43 149.0 2.9 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Histone PF00125.19 EIW79044.1 - 4.2e-30 103.6 0.8 6.7e-30 103.0 0.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIW79044.1 - 1.4e-05 25.1 0.1 2.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EIW79044.1 - 0.00068 19.6 0.1 0.0014 18.6 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EIW79044.1 - 0.016 14.8 0.1 0.026 14.2 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EIW79044.1 - 0.2 10.8 2.2 0.23 10.6 1.5 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 EIW79045.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIW79045.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EIW79045.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EIW79045.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EIW79045.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EIW79045.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit F-box-like PF12937.2 EIW79046.1 - 1.8e-10 40.3 0.2 1.8e-10 40.3 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIW79046.1 - 0.074 12.7 0.0 0.22 11.2 0.0 1.8 1 0 0 1 1 1 0 F-box domain RhoGAP PF00620.22 EIW79048.1 - 3.2e-46 156.7 0.3 6.7e-46 155.6 0.0 1.6 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 EIW79048.1 - 4.3e-16 58.8 1.9 6.7e-15 55.0 0.0 2.5 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DivIC PF04977.10 EIW79048.1 - 0.0039 16.6 7.2 0.0079 15.6 4.0 2.2 2 0 0 2 2 2 1 Septum formation initiator Baculo_PEP_C PF04513.7 EIW79048.1 - 0.043 13.6 0.6 8.2 6.2 0.0 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 EIW79048.1 - 0.074 12.9 1.1 7.9 6.4 0.2 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) DUF2347 PF09804.4 EIW79048.1 - 0.15 11.3 0.9 0.26 10.5 0.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) PA26 PF04636.8 EIW79048.1 - 0.35 9.5 4.8 0.52 8.9 3.3 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SlyX PF04102.7 EIW79048.1 - 1.4 9.3 6.3 1.4 9.3 1.5 3.0 2 1 1 3 3 3 0 SlyX TMPIT PF07851.8 EIW79048.1 - 1.7 7.6 6.6 1.7 7.6 3.4 1.7 2 0 0 2 2 2 0 TMPIT-like protein Nucleopor_Nup85 PF07575.8 EIW79049.1 - 7.3e-57 192.8 0.0 2.3e-56 191.1 0.0 1.6 1 1 0 1 1 1 1 Nup85 Nucleoporin BRK PF07533.11 EIW79049.1 - 0.11 11.9 0.2 3.6 7.1 0.0 2.7 3 0 0 3 3 3 0 BRK domain Asp PF00026.18 EIW79050.1 - 8.8e-69 232.1 7.4 1.2e-68 231.6 5.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW79050.1 - 3.4e-07 30.3 3.1 4.9e-06 26.5 1.1 3.1 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIW79050.1 - 0.0049 16.4 0.2 0.11 12.0 0.1 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal Histone PF00125.19 EIW79051.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIW79051.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EIW79051.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EIW79051.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EIW79051.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EIW79051.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Histone PF00125.19 EIW79052.1 - 4.2e-30 103.6 0.8 6.7e-30 103.0 0.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIW79052.1 - 1.4e-05 25.1 0.1 2.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EIW79052.1 - 0.00068 19.6 0.1 0.0014 18.6 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EIW79052.1 - 0.016 14.8 0.1 0.026 14.2 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EIW79052.1 - 0.2 10.8 2.2 0.23 10.6 1.5 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T NACHT PF05729.7 EIW79053.1 - 6.2e-11 42.2 0.0 3.5e-10 39.7 0.0 2.1 2 0 0 2 2 2 1 NACHT domain WD40 PF00400.27 EIW79053.1 - 1.2e-08 34.4 5.6 1.5e-05 24.6 0.1 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat AAA_16 PF13191.1 EIW79053.1 - 2.8e-07 30.7 2.1 1.2e-06 28.6 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain Arch_ATPase PF01637.13 EIW79053.1 - 3.7e-05 23.5 0.0 6.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_22 PF13401.1 EIW79053.1 - 0.0043 17.1 0.0 0.015 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIW79053.1 - 0.0057 15.7 0.0 0.012 14.7 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin TruB_C PF09142.6 EIW79053.1 - 0.0095 15.5 0.1 2.6 7.7 0.0 3.0 2 0 0 2 2 2 1 tRNA Pseudouridine synthase II, C terminal PRK PF00485.13 EIW79053.1 - 0.015 14.8 0.0 0.041 13.4 0.0 1.7 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EIW79053.1 - 0.032 14.5 0.0 0.071 13.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EIW79053.1 - 0.033 13.8 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.17 EIW79053.1 - 0.046 13.9 0.0 0.12 12.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA PF00004.24 EIW79053.1 - 0.068 13.3 0.0 0.31 11.2 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF1240 PF06836.7 EIW79054.1 - 2.3 8.5 6.0 1.8 8.8 1.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1240) Methyltransf_16 PF10294.4 EIW79055.1 - 1.8e-14 53.6 0.0 2.7e-09 36.7 0.0 2.3 2 1 0 2 2 2 2 Putative methyltransferase Methyltransf_23 PF13489.1 EIW79055.1 - 0.001 18.8 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Nnf1 PF03980.9 EIW79056.1 - 3.1e-08 33.5 0.5 3.1e-08 33.5 0.3 1.6 2 0 0 2 2 2 1 Nnf1 UPF0242 PF06785.6 EIW79056.1 - 0.0072 15.0 1.7 0.0087 14.7 1.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) BLOC1_2 PF10046.4 EIW79056.1 - 0.0082 16.2 1.5 0.037 14.1 0.3 2.1 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mod_r PF07200.8 EIW79056.1 - 0.01 15.7 0.5 0.019 14.9 0.4 1.4 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Spc24 PF08286.6 EIW79056.1 - 0.074 12.7 1.1 0.12 12.0 0.7 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Macoilin PF09726.4 EIW79056.1 - 0.078 11.2 4.1 0.098 10.9 2.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Herpes_BLRF2 PF05812.7 EIW79056.1 - 0.22 11.3 5.5 0.13 12.0 2.0 1.8 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein Mnd1 PF03962.10 EIW79056.1 - 0.29 10.7 3.8 0.071 12.7 0.4 1.6 2 1 0 2 2 2 0 Mnd1 family IncA PF04156.9 EIW79056.1 - 0.93 9.0 5.4 1.1 8.8 3.6 1.4 1 1 0 1 1 1 0 IncA protein Glyco_transf_21 PF13506.1 EIW79057.1 - 0.028 13.7 0.3 0.24 10.6 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 21 DUF1240 PF06836.7 EIW79057.1 - 1.2 9.4 6.5 0.16 12.2 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) HET PF06985.6 EIW79058.1 - 3.6e-18 66.0 7.2 2.3e-15 56.9 1.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Sirohm_synth_C PF14823.1 EIW79058.1 - 0.082 12.2 0.2 0.25 10.6 0.1 1.8 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal PARP PF00644.15 EIW79059.1 - 1.2e-13 50.9 1.0 9.3e-11 41.5 0.1 2.1 2 0 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain zf-RING_2 PF13639.1 EIW79060.1 - 7.1e-09 35.3 7.4 1.4e-07 31.1 2.9 2.4 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EIW79060.1 - 4.2e-06 26.7 6.9 3.2e-05 23.9 4.8 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EIW79060.1 - 1.1e-05 25.0 0.3 3.5e-05 23.3 0.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW79060.1 - 0.00042 19.9 1.4 0.00042 19.9 1.0 1.9 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EIW79060.1 - 0.00068 19.4 1.1 0.0024 17.6 0.8 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EIW79060.1 - 0.001 19.0 3.9 0.001 19.0 2.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW79060.1 - 0.0014 18.2 2.0 0.0014 18.2 1.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EIW79060.1 - 2.5 7.7 4.7 0.57 9.8 0.7 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain LRR_6 PF13516.1 EIW79061.1 - 1.7e-05 24.4 3.1 0.074 13.1 0.0 6.6 8 0 0 8 8 8 1 Leucine Rich repeat LRR_8 PF13855.1 EIW79061.1 - 5.5e-05 22.8 0.4 0.028 14.1 0.0 4.1 4 1 1 5 5 5 1 Leucine rich repeat LRR_7 PF13504.1 EIW79061.1 - 0.017 15.2 5.1 10 6.8 0.1 6.0 8 0 0 8 8 8 0 Leucine rich repeat LRR_4 PF12799.2 EIW79061.1 - 0.073 12.7 5.7 11 5.7 0.2 5.0 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIW79061.1 - 0.24 11.5 1.1 11 6.5 0.0 4.2 5 1 0 5 5 5 0 Leucine Rich Repeat CENP-T PF15511.1 EIW79061.1 - 1.4 8.1 19.9 2.5 7.2 0.7 2.1 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T adh_short PF00106.20 EIW79062.1 - 2.6e-21 76.2 0.5 4.8e-21 75.3 0.4 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW79062.1 - 5.5e-08 32.6 0.2 1.1e-07 31.7 0.1 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EIW79062.1 - 1.8e-05 24.6 0.0 2.8e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EIW79062.1 - 0.00029 20.3 0.1 0.00051 19.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW79062.1 - 0.0031 17.5 0.2 0.0063 16.5 0.2 1.6 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EIW79062.1 - 0.005 15.7 0.3 0.015 14.2 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EIW79062.1 - 0.011 14.9 0.2 0.016 14.4 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family NAD_binding_4 PF07993.7 EIW79062.1 - 0.092 11.6 0.2 0.26 10.1 0.1 1.7 1 1 0 1 1 1 0 Male sterility protein L_HGMIC_fpl PF10242.4 EIW79064.1 - 0.016 15.2 0.7 0.018 15.0 0.5 1.1 1 0 0 1 1 1 0 Lipoma HMGIC fusion partner-like protein DUF3917 PF13055.1 EIW79064.1 - 0.039 14.1 3.0 0.061 13.5 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3917) HET PF06985.6 EIW79065.1 - 1.7e-18 67.1 4.3 1.6e-15 57.4 0.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Sirohm_synth_C PF14823.1 EIW79065.1 - 0.033 13.4 0.0 0.1 11.9 0.0 1.8 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal Glyco_hydro_47 PF01532.15 EIW79066.1 - 2.4e-129 431.9 0.0 2.7e-129 431.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Asp PF00026.18 EIW79067.1 - 7.3e-75 252.1 1.8 8.9e-75 251.8 1.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EIW79067.1 - 1.5e-05 25.4 1.1 0.043 14.3 0.3 3.3 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EIW79067.1 - 6.3e-05 22.9 2.8 0.00043 20.2 0.7 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIW79067.1 - 0.019 14.5 0.0 0.046 13.2 0.0 1.7 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Evr1_Alr PF04777.8 EIW79068.1 - 4.7e-28 96.9 0.3 8.6e-28 96.0 0.0 1.5 2 0 0 2 2 2 1 Erv1 / Alr family DUF755 PF05501.6 EIW79068.1 - 7.3 6.6 8.2 0.13 12.2 1.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Pkinase PF00069.20 EIW79069.1 - 4.2e-40 137.5 0.0 6.9e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW79069.1 - 6.2e-39 133.6 0.0 8.6e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EIW79070.1 - 1.7e-43 148.6 0.0 2.2e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW79070.1 - 4e-34 117.8 0.0 4.7e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW79070.1 - 0.00028 19.9 0.0 0.00041 19.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW79070.1 - 0.0019 17.9 0.0 0.13 11.9 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EIW79070.1 - 0.046 12.7 0.0 0.076 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EIW79070.1 - 0.18 10.5 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase PF00069.20 EIW79071.1 - 2.1e-44 151.6 0.0 4.1e-44 150.6 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW79071.1 - 3.7e-34 117.9 0.0 5.3e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW79071.1 - 0.014 14.3 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EIW79071.1 - 0.028 13.4 0.1 0.1 11.6 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW79071.1 - 0.059 13.0 0.0 0.25 11.0 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family PHD PF00628.24 EIW79072.1 - 1.5e-11 43.7 4.2 2.5e-11 43.0 2.9 1.3 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EIW79072.1 - 0.00021 20.4 1.3 0.00037 19.7 0.9 1.4 1 0 0 1 1 1 1 PHD-finger zf-CW PF07496.10 EIW79072.1 - 0.018 14.7 0.9 0.035 13.8 0.6 1.4 1 0 0 1 1 1 0 CW-type Zinc Finger Prok-RING_1 PF14446.1 EIW79072.1 - 0.026 14.2 4.3 0.022 14.4 1.5 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PS_Dcarbxylase PF02666.10 EIW79074.1 - 2.2e-44 151.2 0.0 3e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase WD40 PF00400.27 EIW79075.1 - 9.5e-14 50.6 0.1 0.00035 20.3 0.0 4.2 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 EIW79075.1 - 0.015 13.5 0.0 0.071 11.2 0.0 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Acetyltransf_3 PF13302.1 EIW79076.1 - 2.1e-17 63.6 0.0 2.9e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW79076.1 - 8.5e-15 54.5 0.0 1.2e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EIW79076.1 - 1.2e-09 38.3 0.1 1.5e-09 37.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIW79076.1 - 1.7e-05 24.8 0.1 2.6e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIW79076.1 - 2.6e-05 24.1 0.0 3.3e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIW79076.1 - 0.0011 19.0 0.0 0.0018 18.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AP2 PF00847.15 EIW79076.1 - 1.4 9.1 5.2 12 6.1 0.0 3.4 3 1 1 4 4 4 0 AP2 domain Rhomboid PF01694.17 EIW79077.1 - 1.4e-13 51.1 15.0 1.5e-06 28.2 2.3 3.5 3 1 0 3 3 3 2 Rhomboid family DUF307 PF03733.8 EIW79078.1 - 5.3 7.5 8.3 9.4 6.7 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF307) Pyr_redox_3 PF13738.1 EIW79080.1 - 3.7e-23 82.6 0.0 1.1e-22 81.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIW79080.1 - 7.7e-15 54.0 0.0 3.6e-14 51.8 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EIW79080.1 - 1.3e-12 47.3 0.0 1.1e-09 37.7 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EIW79080.1 - 2.5e-11 43.8 0.0 6.5e-09 35.9 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW79080.1 - 4.9e-08 33.2 0.0 0.034 14.5 0.0 3.8 5 0 0 5 5 4 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW79080.1 - 4.6e-07 29.7 0.1 1.8e-05 24.6 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EIW79080.1 - 7.9e-07 28.4 0.2 5.9e-06 25.5 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EIW79080.1 - 9.9e-05 21.3 0.4 0.0046 15.9 0.0 3.0 3 0 0 3 3 3 1 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EIW79080.1 - 0.0001 21.4 0.0 0.011 14.8 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.17 EIW79080.1 - 0.00063 18.7 0.0 0.58 8.9 0.0 3.1 3 0 0 3 3 3 1 Glucose inhibited division protein A HI0933_like PF03486.9 EIW79080.1 - 0.00092 17.7 0.1 0.0029 16.1 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 EIW79080.1 - 0.0037 17.0 0.1 1.1 9.0 0.0 2.5 2 1 0 2 2 2 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EIW79080.1 - 0.0051 16.4 0.0 0.2 11.3 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EIW79080.1 - 0.059 12.1 0.3 0.22 10.3 0.1 1.9 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 EIW79080.1 - 0.06 12.2 0.0 3.5 6.4 0.0 2.9 4 0 0 4 4 4 0 Lycopene cyclase protein ApbA PF02558.11 EIW79080.1 - 0.14 11.6 0.0 3.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Thi4 PF01946.12 EIW79080.1 - 0.14 11.2 0.0 0.45 9.5 0.0 1.8 2 0 0 2 2 2 0 Thi4 family UDPG_MGDP_dh_N PF03721.9 EIW79080.1 - 0.2 11.0 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Peptidase_M28 PF04389.12 EIW79081.1 - 5.6e-27 94.6 0.0 1.1e-26 93.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EIW79081.1 - 2.2e-06 27.3 0.0 3.2e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 FGGY_N PF00370.16 EIW79082.1 - 5.7e-61 205.9 0.7 2.2e-59 200.7 0.5 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EIW79082.1 - 1.7e-60 204.0 0.8 2.4e-60 203.5 0.5 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Pyr_redox_3 PF13738.1 EIW79086.1 - 9.7e-25 87.8 0.0 1.9e-23 83.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIW79086.1 - 4.2e-14 51.6 0.0 2.3e-09 36.0 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EIW79086.1 - 1.3e-13 51.3 0.0 7.1e-12 45.6 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW79086.1 - 3.2e-10 39.4 0.0 1.8e-08 33.6 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EIW79086.1 - 2.1e-07 31.2 0.2 0.002 18.4 0.1 3.0 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW79086.1 - 3.8e-07 29.3 0.0 0.0002 20.3 0.0 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW79086.1 - 4.8e-06 26.5 0.0 4.8e-05 23.2 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EIW79086.1 - 1.5e-05 24.2 0.0 0.00011 21.3 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EIW79086.1 - 3.5e-05 22.4 0.1 0.00012 20.6 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein 2-Hacid_dh_C PF02826.14 EIW79086.1 - 5.7e-05 22.3 0.0 0.00066 18.8 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EIW79086.1 - 0.0001 22.0 0.3 0.16 11.6 0.0 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EIW79086.1 - 0.00056 18.8 0.0 0.11 11.2 0.0 2.8 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EIW79086.1 - 0.00065 18.6 0.0 0.0019 17.1 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EIW79086.1 - 0.0019 17.9 0.1 1.7 8.3 0.0 3.0 2 1 1 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EIW79086.1 - 0.0024 16.8 0.0 0.041 12.7 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.12 EIW79086.1 - 0.0039 16.3 0.0 0.022 13.8 0.0 2.1 3 0 0 3 3 3 1 Thi4 family IlvN PF07991.7 EIW79086.1 - 0.0046 16.3 0.0 3.4 6.9 0.0 2.4 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain Shikimate_DH PF01488.15 EIW79086.1 - 0.018 15.1 0.0 0.89 9.6 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase DUF4440 PF14534.1 EIW79086.1 - 0.025 14.7 0.1 0.092 12.9 0.0 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4440) UDPG_MGDP_dh_N PF03721.9 EIW79086.1 - 0.027 13.8 0.0 0.041 13.2 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 EIW79086.1 - 0.033 13.6 0.0 0.45 9.9 0.0 2.4 2 1 1 3 3 3 0 Ketopantoate reductase PanE/ApbA DUF498 PF04430.9 EIW79086.1 - 0.039 13.5 0.1 13 5.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) SnoaL_2 PF12680.2 EIW79086.1 - 0.054 13.8 0.2 0.17 12.2 0.1 1.9 2 0 0 2 2 1 0 SnoaL-like domain FAD_oxidored PF12831.2 EIW79086.1 - 0.055 12.5 0.0 0.084 11.9 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase SBP_bac_5 PF00496.17 EIW79086.1 - 0.061 12.1 0.1 0.097 11.4 0.0 1.2 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle Trp_halogenase PF04820.9 EIW79086.1 - 0.066 11.8 0.8 1.6 7.2 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase MtrD PF04207.7 EIW79086.1 - 0.12 11.7 0.0 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit D Zip PF02535.17 EIW79087.1 - 5.5e-55 186.5 7.0 6.4e-55 186.3 4.9 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter zf-HIT PF04438.11 EIW79088.1 - 5.6e-09 35.4 8.4 8.5e-09 34.9 5.8 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-Apc11 PF12861.2 EIW79088.1 - 0.054 13.3 0.6 0.1 12.4 0.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger LTXXQ PF07813.7 EIW79088.1 - 0.11 12.9 1.2 0.35 11.3 0.1 2.4 2 1 0 2 2 2 0 LTXXQ motif family protein zf-B_box PF00643.19 EIW79088.1 - 3.6 7.5 8.7 5.8 6.9 6.1 1.3 1 0 0 1 1 1 0 B-box zinc finger Ecl1 PF12855.2 EIW79088.1 - 6.8 6.0 7.9 14 5.0 5.5 1.5 1 0 0 1 1 1 0 Life-span regulatory factor DEAD PF00270.24 EIW79089.1 - 1.3e-37 128.9 0.3 1.9e-37 128.3 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW79089.1 - 9.2e-20 70.2 0.1 2.3e-10 40.1 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EIW79089.1 - 0.0003 20.6 0.0 0.0012 18.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Trypan_PARP PF05887.6 EIW79089.1 - 0.054 13.3 17.9 0.12 12.2 12.4 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4604 PF15377.1 EIW79089.1 - 0.069 13.3 13.0 0.13 12.4 9.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) AAA_22 PF13401.1 EIW79089.1 - 0.082 13.0 0.0 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain CMS1 PF14617.1 EIW79089.1 - 0.14 11.1 2.5 0.16 10.9 0.0 2.1 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Neisseria_TspB PF05616.8 EIW79089.1 - 0.39 9.0 7.4 0.57 8.4 5.1 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Presenilin PF01080.12 EIW79089.1 - 0.96 8.1 4.0 1.7 7.4 2.8 1.2 1 0 0 1 1 1 0 Presenilin Apt1 PF10351.4 EIW79089.1 - 1.1 8.0 6.3 2.7 6.7 4.4 1.6 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pol_alpha_B_N PF08418.5 EIW79089.1 - 4.7 6.6 13.0 1.5 8.2 5.8 2.0 2 0 0 2 2 2 0 DNA polymerase alpha subunit B N-terminal RR_TM4-6 PF06459.7 EIW79089.1 - 4.9 6.9 9.8 9.2 6.0 6.8 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MFS_1 PF07690.11 EIW79090.1 - 1.1e-55 188.7 44.0 2.2e-55 187.7 29.9 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIW79090.1 - 7.2e-24 83.9 16.4 9.5e-24 83.5 11.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIW79090.1 - 5.3e-12 45.0 13.8 5.3e-12 45.0 9.5 3.5 2 1 1 3 3 3 2 Sugar (and other) transporter DUF373 PF04123.8 EIW79090.1 - 0.32 9.9 12.0 0.36 9.7 6.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF4131 PF13567.1 EIW79090.1 - 1.2 8.5 20.5 9.6 5.5 0.6 4.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) DUF3040 PF11239.3 EIW79090.1 - 6.6 6.8 12.6 1.1 9.3 0.7 4.4 1 1 3 4 4 4 0 Protein of unknown function (DUF3040) Glyco_hydro_3 PF00933.16 EIW79091.1 - 2.1e-76 256.7 0.0 3.5e-76 256.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIW79091.1 - 1.7e-67 227.2 0.0 8.5e-67 224.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIW79091.1 - 7.1e-22 77.1 0.0 1.4e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EIW79091.1 - 3.8e-08 33.0 0.0 8.7e-08 31.9 0.0 1.5 1 0 0 1 1 1 1 PA14 domain ANTH PF07651.11 EIW79092.1 - 3.4e-54 183.4 0.0 4.6e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EIW79092.1 - 0.0071 16.2 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 ENTH domain F-box PF00646.28 EIW79092.1 - 0.13 11.9 0.2 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 F-box domain DUF3638 PF12340.3 EIW79093.1 - 1.4e-78 263.0 0.3 2.9e-78 262.0 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EIW79093.1 - 3.9e-17 61.0 0.0 8.6e-17 59.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) SKN1 PF03935.10 EIW79094.1 - 0.12 10.4 0.0 0.14 10.2 0.0 1.1 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) Fork_head PF00250.13 EIW79095.1 - 3.8e-05 23.6 0.0 5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Fork head domain Pkinase PF00069.20 EIW79096.1 - 1.4e-07 30.9 0.0 2.2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW79096.1 - 0.014 14.4 0.0 0.024 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase MmlI PF09448.5 EIW79096.1 - 0.025 14.3 0.2 1.7 8.3 0.0 2.7 3 0 0 3 3 3 0 Methylmuconolactone methyl-isomerase Glyco_hydro_47 PF01532.15 EIW79097.1 - 1.2e-125 419.7 0.3 1.7e-125 419.2 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 SHNi-TPR PF10516.4 EIW79098.1 - 1.9e-16 59.0 0.0 2e-14 52.5 0.0 2.5 2 0 0 2 2 2 1 SHNi-TPR TPR_11 PF13414.1 EIW79098.1 - 1.7e-13 49.9 1.2 5.7e-06 25.8 0.0 2.8 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 EIW79098.1 - 3.2e-13 49.4 5.2 8.3e-06 25.6 0.6 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIW79098.1 - 1.8e-07 30.5 5.8 0.022 14.6 0.0 4.5 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIW79098.1 - 1.8e-07 30.4 4.8 0.014 15.0 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIW79098.1 - 5.5e-05 23.7 5.5 0.075 13.7 1.4 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EIW79098.1 - 6.8e-05 22.3 1.9 0.35 10.7 0.2 3.5 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIW79098.1 - 0.00014 21.4 0.4 0.027 14.2 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EIW79098.1 - 0.00071 19.4 4.7 0.013 15.4 1.2 3.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIW79098.1 - 0.0041 17.4 8.4 0.27 11.5 0.0 3.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIW79098.1 - 5.9 7.8 10.8 9.2 7.2 0.5 4.3 4 1 0 4 4 3 0 Tetratricopeptide repeat Aldedh PF00171.17 EIW79099.1 - 1.2e-16 60.1 5.1 1.5e-15 56.5 1.3 2.4 2 1 0 2 2 2 2 Aldehyde dehydrogenase family Peptidase_S10 PF00450.17 EIW79100.1 - 1.3e-65 222.2 0.0 2.2e-65 221.4 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase Paf1 PF03985.8 EIW79101.1 - 1.7e-48 165.5 0.0 2.2e-48 165.0 0.0 1.0 1 0 0 1 1 1 1 Paf1 zf-DHHC PF01529.15 EIW79102.1 - 5.5e-26 91.0 0.0 1.6e-25 89.4 0.0 1.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase Yip1 PF04893.12 EIW79102.1 - 5.8 6.3 12.8 2.7 7.4 4.7 2.6 2 1 0 2 2 2 0 Yip1 domain DPBB_1 PF03330.13 EIW79103.1 - 5.3e-06 26.3 0.2 1.4e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DSPc PF00782.15 EIW79104.1 - 1e-33 115.7 0.0 1.3e-33 115.3 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIW79104.1 - 0.00011 21.6 0.0 0.00018 20.9 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EIW79104.1 - 0.0031 16.8 0.0 0.0053 16.1 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EIW79104.1 - 0.0033 17.6 0.2 0.31 11.2 0.0 2.3 1 1 1 2 2 2 1 Tyrosine phosphatase family Init_tRNA_PT PF04179.7 EIW79104.1 - 0.005 15.7 0.4 0.01 14.7 0.1 1.4 1 1 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase CDKN3 PF05706.7 EIW79104.1 - 0.0094 15.4 0.1 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Fork_head PF00250.13 EIW79105.1 - 2.3e-21 75.6 0.0 1.7e-09 37.6 0.0 2.3 2 0 0 2 2 2 2 Fork head domain Med4 PF10018.4 EIW79106.1 - 6e-22 77.9 0.0 8.3e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Ad_cyc_g-alpha PF08509.6 EIW79106.1 - 8.6 5.7 10.3 11 5.4 0.4 3.2 3 0 0 3 3 3 0 Adenylate cyclase G-alpha binding domain Aminotran_3 PF00202.16 EIW79107.1 - 2.5e-70 236.9 0.1 3.4e-70 236.5 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III HECT PF00632.20 EIW79108.1 - 2.7e-83 279.7 0.0 4.2e-83 279.1 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.18 EIW79108.1 - 0.039 13.7 0.4 1.5 8.7 0.0 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat zf-CCHC PF00098.18 EIW79109.1 - 8.2e-05 22.3 5.0 0.00018 21.2 3.5 1.6 1 0 0 1 1 1 1 Zinc knuckle RVP_2 PF08284.6 EIW79109.1 - 0.00016 21.5 0.0 0.0012 18.7 0.0 2.2 1 1 0 1 1 1 1 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIW79109.1 - 0.0096 15.7 0.2 0.2 11.4 0.0 2.9 3 0 0 3 3 3 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EIW79109.1 - 0.039 14.4 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease DUF327 PF03885.8 EIW79109.1 - 1.1 9.0 5.4 1.1 9.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF327) DUF230 PF03003.11 EIW79110.1 - 0.0099 15.4 0.3 0.014 14.9 0.2 1.3 1 0 0 1 1 1 1 Poxvirus proteins of unknown function Rho_Binding PF08912.6 EIW79110.1 - 0.029 14.6 1.4 0.044 14.0 0.3 1.7 2 1 0 2 2 2 0 Rho Binding ApoO PF09769.4 EIW79110.1 - 0.098 12.3 0.2 0.12 12.1 0.2 1.3 1 1 0 1 1 1 0 Apolipoprotein O SBF PF01758.11 EIW79111.1 - 0.018 14.4 0.2 0.02 14.3 0.1 1.1 1 0 0 1 1 1 0 Sodium Bile acid symporter family DUF4398 PF14346.1 EIW79113.1 - 0.12 12.4 0.2 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) DHH PF01368.15 EIW79116.1 - 0.03 13.9 0.0 0.035 13.7 0.0 1.1 1 0 0 1 1 1 0 DHH family Fijivirus_P9-2 PF06837.6 EIW79117.1 - 0.025 13.7 1.7 0.05 12.7 1.1 1.5 1 0 0 1 1 1 0 Fijivirus P9-2 protein Retrotrans_gag PF03732.12 EIW79120.1 - 0.013 15.5 0.9 0.4 10.7 0.0 2.3 2 0 0 2 2 2 0 Retrotransposon gag protein zf-CCHC PF00098.18 EIW79120.1 - 0.2 11.6 3.3 0.61 10.1 2.3 1.8 1 1 0 1 1 1 0 Zinc knuckle Nop14 PF04147.7 EIW79123.1 - 0.0035 15.3 15.4 0.0042 15.0 10.7 1.1 1 0 0 1 1 1 1 Nop14-like family Ycf1 PF05758.7 EIW79123.1 - 0.0096 13.6 4.8 0.011 13.5 3.3 1.1 1 0 0 1 1 1 1 Ycf1 Merozoite_SPAM PF07133.6 EIW79123.1 - 0.013 15.4 25.1 0.021 14.7 17.4 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) ADP_ribosyl_GH PF03747.9 EIW79123.1 - 0.025 14.3 0.4 0.045 13.5 0.3 1.3 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase DUF2457 PF10446.4 EIW79123.1 - 0.026 13.2 16.3 0.042 12.5 11.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RAB3GAP2_C PF14656.1 EIW79123.1 - 0.048 11.7 5.1 0.076 11.1 3.5 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus DUF4512 PF14975.1 EIW79123.1 - 0.059 14.2 1.6 0.18 12.6 1.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) HSP90 PF00183.13 EIW79123.1 - 0.075 11.4 17.8 0.11 10.9 12.3 1.2 1 0 0 1 1 1 0 Hsp90 protein SspB PF04386.8 EIW79123.1 - 0.086 12.4 9.2 0.16 11.5 6.4 1.4 1 0 0 1 1 1 0 Stringent starvation protein B TRAP_alpha PF03896.11 EIW79123.1 - 0.089 11.7 11.4 0.14 11.1 7.9 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RP-C_C PF11800.3 EIW79123.1 - 0.12 12.0 2.5 0.19 11.3 1.7 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Tim54 PF11711.3 EIW79123.1 - 0.12 10.9 6.8 0.18 10.3 4.7 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DDHD PF02862.12 EIW79123.1 - 0.12 12.1 7.8 0.18 11.5 5.4 1.2 1 0 0 1 1 1 0 DDHD domain Spore_coat_CotO PF14153.1 EIW79123.1 - 0.13 11.7 15.8 0.24 10.8 10.9 1.4 1 0 0 1 1 1 0 Spore coat protein CotO DUF913 PF06025.7 EIW79123.1 - 0.13 10.9 2.5 0.19 10.4 1.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Fmp27 PF10344.4 EIW79123.1 - 0.17 9.4 6.2 0.24 9.0 4.3 1.1 1 0 0 1 1 1 0 Mitochondrial protein from FMP27 DUF2828 PF11443.3 EIW79123.1 - 0.25 9.4 2.6 0.3 9.2 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Herpes_UL25 PF01499.11 EIW79123.1 - 0.26 9.5 1.8 0.38 9.0 1.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Nucleoside_tran PF01733.13 EIW79123.1 - 0.28 10.3 0.7 0.41 9.7 0.5 1.2 1 0 0 1 1 1 0 Nucleoside transporter TFIIF_alpha PF05793.7 EIW79123.1 - 0.31 9.3 20.5 0.42 8.9 14.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) VID27 PF08553.5 EIW79123.1 - 0.46 8.6 15.8 0.63 8.1 11.0 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein RR_TM4-6 PF06459.7 EIW79123.1 - 0.48 10.2 15.2 0.71 9.7 10.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CDC45 PF02724.9 EIW79123.1 - 0.55 8.1 13.9 0.83 7.6 9.6 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3381 PF11861.3 EIW79123.1 - 0.57 9.6 24.8 1 8.8 17.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Zip PF02535.17 EIW79123.1 - 0.58 9.1 4.6 0.77 8.7 3.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RNase_H2-Ydr279 PF09468.5 EIW79123.1 - 0.62 9.1 6.0 0.91 8.6 4.2 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Pox_Ag35 PF03286.9 EIW79123.1 - 0.74 9.3 12.5 1.5 8.3 8.7 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Prog_receptor PF02161.10 EIW79123.1 - 0.98 8.1 8.6 1.4 7.6 6.0 1.2 1 0 0 1 1 1 0 Progesterone receptor Anoctamin PF04547.7 EIW79123.1 - 1.1 7.8 5.2 1.1 7.8 2.8 1.5 2 0 0 2 2 2 0 Calcium-activated chloride channel RasGAP PF00616.14 EIW79123.1 - 1.1 8.8 6.5 2.1 7.9 4.5 1.4 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase SID-1_RNA_chan PF13965.1 EIW79123.1 - 1.2 7.2 3.6 1.6 6.7 2.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Orbi_VP1 PF05788.7 EIW79123.1 - 1.3 6.1 6.0 1.7 5.7 4.1 1.1 1 0 0 1 1 1 0 Orbivirus RNA-dependent RNA polymerase (VP1) Sporozoite_P67 PF05642.6 EIW79123.1 - 1.7 6.4 4.9 2.1 6.0 3.4 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen AIF_C PF14721.1 EIW79123.1 - 2.3 8.4 5.4 5.2 7.3 3.7 1.5 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term eIF-4B PF06273.6 EIW79123.1 - 2.7 6.6 11.1 3.8 6.1 7.7 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B Daxx PF03344.10 EIW79123.1 - 2.9 6.2 24.9 4.6 5.6 17.3 1.2 1 0 0 1 1 1 0 Daxx Family YqfQ PF14181.1 EIW79123.1 - 2.9 7.8 15.5 5.1 7.1 10.7 1.3 1 0 0 1 1 1 0 YqfQ-like protein Peptidase_S49_N PF08496.5 EIW79123.1 - 3.2 7.5 7.9 6.2 6.5 5.5 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal OAD_gamma PF04277.8 EIW79123.1 - 3.8 7.9 6.0 12 6.3 4.2 1.8 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain DNA_pol_phi PF04931.8 EIW79123.1 - 3.9 5.1 28.1 5.6 4.6 19.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi Afi1 PF07792.7 EIW79123.1 - 4.3 7.3 11.6 9.1 6.2 8.0 1.4 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Cytomega_UL84 PF06284.6 EIW79123.1 - 5.7 5.2 6.1 7 4.9 4.2 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein Sec62 PF03839.11 EIW79123.1 - 6.9 6.0 7.8 11 5.3 5.4 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4187 PF13821.1 EIW79124.1 - 0.12 11.9 1.4 0.26 10.9 1.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) CENP-B_dimeris PF09026.5 EIW79125.1 - 0.0037 17.4 2.8 0.005 17.0 1.9 1.2 1 0 0 1 1 1 1 Centromere protein B dimerisation domain Tubulin_C PF03953.12 EIW79127.1 - 7.2e-06 26.0 0.0 1.5e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain DUF3987 PF13148.1 EIW79129.1 - 0.007 14.9 0.0 0.0072 14.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) Cytochrome_C554 PF13435.1 EIW79129.1 - 0.044 13.8 0.5 0.045 13.8 0.3 1.2 1 0 0 1 1 1 0 Cytochrome c554 and c-prime RVT_1 PF00078.22 EIW79134.1 - 0.0015 17.9 0.0 0.0018 17.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DDE_3 PF13358.1 EIW79140.1 - 0.028 14.1 0.0 0.059 13.1 0.0 1.4 1 1 0 1 1 1 0 DDE superfamily endonuclease CRAL_TRIO PF00650.15 EIW79141.1 - 1.2e-25 89.8 0.0 2e-25 89.1 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EIW79141.1 - 0.0074 16.4 0.0 0.032 14.3 0.0 2.2 1 1 0 1 1 1 1 CRAL/TRIO, N-terminal domain TPT PF03151.11 EIW79142.1 - 8.8e-33 113.1 6.5 8.8e-33 113.1 4.5 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EIW79142.1 - 5.9e-15 54.9 16.9 7.6e-15 54.6 11.7 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EIW79142.1 - 9.9e-12 45.0 26.5 3.1e-09 36.9 5.4 2.9 2 1 1 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EIW79142.1 - 0.0092 15.1 5.2 0.18 10.8 0.0 2.9 2 1 0 2 2 2 1 Nucleotide-sugar transporter Ribosomal_S4e PF00900.15 EIW79143.1 - 8.3e-31 105.4 0.6 2.3e-30 104.0 0.1 2.0 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 EIW79143.1 - 3.4e-21 74.8 3.8 1.1e-20 73.1 2.8 1.8 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.20 EIW79143.1 - 1e-07 31.2 0.0 2.3e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EIW79143.1 - 1e-05 25.0 1.6 3.3e-05 23.4 1.1 2.0 1 0 0 1 1 1 1 KOW motif DRMBL PF07522.9 EIW79144.1 - 1.2e-28 99.2 0.0 2.2e-28 98.4 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EIW79144.1 - 6.5e-11 42.1 0.1 1.3e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIW79144.1 - 0.018 14.6 0.9 0.041 13.5 0.6 1.7 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily ZZ PF00569.12 EIW79145.1 - 5.4e-18 64.2 56.0 4.8e-07 29.2 2.4 6.2 6 0 0 6 6 6 4 Zinc finger, ZZ type PB1 PF00564.19 EIW79145.1 - 7.7e-08 31.9 0.1 1.7e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 PB1 domain C1_1 PF00130.17 EIW79145.1 - 4.5 7.0 44.7 3.1 7.6 0.5 5.7 5 0 0 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Uds1 PF15456.1 EIW79146.1 - 1.7 8.6 8.6 1.8 8.5 0.1 3.1 2 1 1 3 3 3 0 Up-regulated During Septation IF4E PF01652.13 EIW79147.1 - 2.4e-47 160.5 0.1 3.1e-47 160.1 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Tmemb_14 PF03647.8 EIW79148.1 - 8.6e-18 64.5 5.6 1.1e-17 64.2 3.9 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C Bundlin PF05307.6 EIW79148.1 - 0.069 13.0 0.1 0.26 11.2 0.0 1.8 1 1 1 2 2 2 0 Bundlin MtrC PF04211.8 EIW79148.1 - 0.1 11.5 2.6 0.1 11.5 1.8 1.1 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit C Methyltransf_11 PF08241.7 EIW79149.1 - 1.5e-10 41.4 0.1 5e-10 39.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW79149.1 - 5.8e-10 38.9 0.0 7.4e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW79149.1 - 3.5e-08 33.9 0.0 5.1e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW79149.1 - 1.7e-07 31.4 0.0 3.2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW79149.1 - 8.2e-05 22.3 0.0 0.0001 22.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW79149.1 - 0.00057 20.3 0.0 0.00094 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EIW79149.1 - 0.043 13.1 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 EIW79149.1 - 0.068 12.8 0.0 0.089 12.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_28 PF02636.12 EIW79150.1 - 8e-34 117.1 0.0 1.3e-33 116.4 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 EIW79150.1 - 0.00032 19.8 0.0 0.00053 19.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 EIW79150.1 - 0.002 18.5 0.0 0.006 17.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW79150.1 - 0.025 15.1 0.0 0.047 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EIW79150.1 - 0.027 14.0 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MMS19_N PF14500.1 EIW79151.1 - 3.9e-91 304.9 0.3 6.4e-89 297.6 0.0 3.6 3 1 1 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.3 EIW79151.1 - 3e-82 276.5 2.9 3e-82 276.5 2.0 2.3 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal HEAT_2 PF13646.1 EIW79151.1 - 2.4e-06 27.7 5.5 0.00082 19.6 0.3 5.5 4 3 1 5 5 5 2 HEAT repeats HEAT PF02985.17 EIW79151.1 - 0.041 13.9 4.9 13 6.1 0.0 4.9 5 0 0 5 5 5 0 HEAT repeat HEAT_EZ PF13513.1 EIW79151.1 - 0.049 14.1 4.9 3.1 8.4 0.1 5.6 6 0 0 6 6 6 0 HEAT-like repeat FF PF01846.14 EIW79152.1 - 1.2e-33 114.7 6.9 9e-12 44.7 0.0 6.2 5 1 1 6 6 6 5 FF domain WW PF00397.21 EIW79152.1 - 1e-15 57.2 13.8 6e-08 32.4 1.1 2.8 2 0 0 2 2 2 2 WW domain TarH PF02203.10 EIW79152.1 - 0.13 12.0 4.7 0.29 10.9 0.1 2.7 2 0 0 2 2 2 0 Tar ligand binding domain homologue Ribosomal_L21p PF00829.16 EIW79153.1 - 1e-13 51.2 0.3 1.2e-13 50.9 0.2 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein ATP-synt_ab PF00006.20 EIW79154.1 - 6e-70 235.0 0.0 1e-69 234.3 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EIW79154.1 - 3.4e-23 82.2 0.3 8.4e-23 81.0 0.0 1.8 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EIW79154.1 - 7.6e-18 64.4 1.5 1.9e-17 63.1 1.0 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF2408 PF10303.4 EIW79155.1 - 5.2e-60 201.4 3.5 3.2e-31 108.2 0.1 5.1 3 2 2 5 5 5 5 Protein of unknown function (DUF2408) Snapin_Pallidin PF14712.1 EIW79155.1 - 0.016 15.4 12.8 2 8.7 0.2 5.7 6 1 0 6 6 6 0 Snapin/Pallidin MscS_porin PF12795.2 EIW79155.1 - 0.026 13.8 9.6 3.4 6.9 0.1 3.3 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain IPK PF03770.11 EIW79155.1 - 0.091 12.3 0.3 0.6 9.7 0.1 2.2 1 1 0 2 2 2 0 Inositol polyphosphate kinase MitMem_reg PF13012.1 EIW79155.1 - 0.13 12.3 5.9 0.11 12.5 0.2 3.5 4 1 0 4 4 4 0 Maintenance of mitochondrial structure and function DUF4446 PF14584.1 EIW79155.1 - 0.52 10.1 5.9 0.78 9.5 0.0 3.4 4 1 2 6 6 6 0 Protein of unknown function (DUF4446) FliT PF05400.8 EIW79155.1 - 0.88 10.0 11.5 1.7 9.0 0.3 4.1 2 1 2 4 4 4 0 Flagellar protein FliT Baculo_PEP_C PF04513.7 EIW79155.1 - 2.5 7.9 9.6 18 5.1 0.6 3.6 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2968 PF11180.3 EIW79155.1 - 6.9 6.0 8.3 0.26 10.6 0.5 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2968) Reo_sigmaC PF04582.7 EIW79155.1 - 8.5 5.4 9.1 1.3 8.1 0.3 3.1 3 1 0 4 4 4 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 EIW79156.1 - 1.3e-47 161.2 32.3 1.4e-47 161.1 22.4 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EIW79156.1 - 2e-14 53.2 30.8 4.2e-10 39.1 10.2 2.1 1 1 1 2 2 2 2 Tropomyosin CENP-F_leu_zip PF10473.4 EIW79156.1 - 0.00018 21.3 31.8 0.033 14.0 6.1 3.0 1 1 2 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 EIW79156.1 - 0.00043 18.1 29.0 0.0006 17.6 20.1 1.1 1 0 0 1 1 1 1 Myosin tail IncA PF04156.9 EIW79156.1 - 0.00079 19.0 21.7 0.0033 17.0 14.9 1.9 1 1 0 1 1 1 1 IncA protein GAS PF13851.1 EIW79156.1 - 0.0033 16.6 28.5 0.047 12.8 8.3 2.4 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 EIW79156.1 - 0.0033 17.2 9.5 0.0033 17.2 6.6 3.2 1 1 2 3 3 3 2 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.1 EIW79156.1 - 0.014 15.3 31.5 0.026 14.4 6.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) DUF3450 PF11932.3 EIW79156.1 - 0.017 14.3 20.0 0.036 13.3 5.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF3287 PF11690.3 EIW79156.1 - 0.019 15.0 1.9 0.019 15.0 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) Phage_GP20 PF06810.6 EIW79156.1 - 0.023 14.1 26.6 0.02 14.3 7.2 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 AAA_27 PF13514.1 EIW79156.1 - 0.025 12.3 22.1 0.03 12.0 15.3 1.1 1 0 0 1 1 1 0 AAA domain ERM PF00769.14 EIW79156.1 - 0.025 14.1 31.5 0.027 14.0 19.9 1.9 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF4164 PF13747.1 EIW79156.1 - 0.027 14.6 21.8 0.28 11.3 6.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) WXG100 PF06013.7 EIW79156.1 - 0.03 14.3 11.4 1.5 8.8 0.1 3.3 2 1 1 3 3 3 0 Proteins of 100 residues with WXG HGD-D PF06050.8 EIW79156.1 - 0.036 12.8 1.9 0.046 12.5 1.3 1.3 1 0 0 1 1 1 0 2-hydroxyglutaryl-CoA dehydratase, D-component WEMBL PF05701.6 EIW79156.1 - 0.038 12.4 28.8 0.073 11.5 20.0 1.5 1 1 0 1 1 1 0 Weak chloroplast movement under blue light FliJ PF02050.11 EIW79156.1 - 0.039 13.9 24.2 0.73 9.8 7.2 2.2 1 1 1 2 2 2 0 Flagellar FliJ protein KLRAQ PF10205.4 EIW79156.1 - 0.04 13.9 17.5 0.06 13.3 2.4 3.0 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein ADIP PF11559.3 EIW79156.1 - 0.055 13.3 25.3 0.82 9.5 6.0 3.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Filament PF00038.16 EIW79156.1 - 0.059 12.8 24.1 0.47 9.8 6.2 2.2 1 1 1 2 2 2 0 Intermediate filament protein Nup54 PF13874.1 EIW79156.1 - 0.097 12.3 19.4 0.06 13.0 4.3 2.8 1 1 2 3 3 3 0 Nucleoporin complex subunit 54 APG6 PF04111.7 EIW79156.1 - 0.12 11.3 31.1 0.089 11.8 12.7 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 BLOC1_2 PF10046.4 EIW79156.1 - 0.14 12.2 19.7 0.56 10.3 4.9 3.0 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Laminin_II PF06009.7 EIW79156.1 - 0.19 11.4 15.8 0.077 12.7 3.8 2.3 1 1 1 2 2 2 0 Laminin Domain II TPR_MLP1_2 PF07926.7 EIW79156.1 - 0.2 11.3 29.7 1.6e+02 2.0 20.3 2.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ATG16 PF08614.6 EIW79156.1 - 0.22 11.3 27.1 0.27 11.0 6.5 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) NBP1 PF08537.5 EIW79156.1 - 0.26 10.4 16.4 0.58 9.3 11.4 1.5 1 1 0 1 1 1 0 Fungal Nap binding protein NBP1 EzrA PF06160.7 EIW79156.1 - 0.31 9.1 23.1 6 4.9 16.0 1.9 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA TMF_TATA_bd PF12325.3 EIW79156.1 - 0.34 10.6 24.9 2.1 8.1 1.0 2.4 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DegS PF05384.6 EIW79156.1 - 0.4 9.8 19.9 0.59 9.3 6.7 2.0 1 1 1 2 2 2 0 Sensor protein DegS TBPIP PF07106.8 EIW79156.1 - 0.45 10.0 24.4 0.43 10.1 5.9 2.5 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) FliD_C PF07195.7 EIW79156.1 - 0.52 9.5 15.1 0.3 10.3 4.7 2.8 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF745 PF05335.8 EIW79156.1 - 0.71 9.3 18.6 2.5 7.5 3.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF4407 PF14362.1 EIW79156.1 - 0.75 8.6 20.1 1.8 7.4 13.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.1 EIW79156.1 - 0.83 8.0 23.5 0.92 7.8 6.8 2.0 1 1 1 2 2 2 0 AAA domain PilJ PF13675.1 EIW79156.1 - 0.86 9.9 11.5 1.5 9.1 0.3 2.9 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF3584 PF12128.3 EIW79156.1 - 0.87 6.8 25.8 0.28 8.4 13.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.4 EIW79156.1 - 0.9 8.4 18.8 1.4 7.7 12.9 1.5 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF972 PF06156.8 EIW79156.1 - 1.1 9.6 22.9 1.2 9.5 5.9 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4140 PF13600.1 EIW79156.1 - 1.1 9.7 18.7 5.2 7.5 4.0 2.8 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) GCN5L1 PF06320.8 EIW79156.1 - 1.2 8.9 13.4 0.094 12.5 5.3 1.9 1 1 1 2 2 2 0 GCN5-like protein 1 (GCN5L1) CCDC155 PF14662.1 EIW79156.1 - 1.2 8.6 28.8 0.36 10.3 8.4 2.2 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 HalX PF08663.5 EIW79156.1 - 1.3 9.0 14.8 6.4 6.8 0.1 4.0 3 1 1 4 4 4 0 HalX domain Fmp27_WPPW PF10359.4 EIW79156.1 - 1.6 7.0 22.1 1.2 7.4 4.7 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Seryl_tRNA_N PF02403.17 EIW79156.1 - 1.6 8.7 25.1 1.3 9.0 10.7 2.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Rootletin PF15035.1 EIW79156.1 - 1.7 8.5 24.6 14 5.5 16.7 1.9 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Spc7 PF08317.6 EIW79156.1 - 2 6.9 24.8 3.7 6.1 7.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein LXG PF04740.7 EIW79156.1 - 2.2 8.0 17.5 2 8.1 5.8 2.4 1 1 1 2 2 2 0 LXG domain of WXG superfamily DUF4201 PF13870.1 EIW79156.1 - 2.6 7.4 26.4 7.4 5.9 11.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Mod_r PF07200.8 EIW79156.1 - 2.6 7.9 24.3 1.7 8.5 7.4 2.6 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein HlyD PF00529.15 EIW79156.1 - 3 7.0 12.5 3.6 6.7 8.7 1.2 1 0 0 1 1 1 0 HlyD family secretion protein DUF948 PF06103.6 EIW79156.1 - 3.1 7.7 10.7 1.5 8.7 0.6 2.9 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Ax_dynein_light PF10211.4 EIW79156.1 - 3.8 7.2 26.4 8.1 6.2 7.5 2.8 1 1 2 3 3 3 0 Axonemal dynein light chain HisKA_3 PF07730.8 EIW79156.1 - 3.9 7.8 9.0 1.7e+02 2.6 0.0 3.6 1 1 1 2 2 2 0 Histidine kinase DUF1664 PF07889.7 EIW79156.1 - 4 7.2 13.7 0.3 10.8 3.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) V_ATPase_I PF01496.14 EIW79156.1 - 4.5 5.0 18.8 1.2 6.9 10.3 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family CENP-Q PF13094.1 EIW79156.1 - 5.1 7.1 27.2 31 4.5 17.9 2.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit SlyX PF04102.7 EIW79156.1 - 5.3 7.4 18.7 3.1 8.2 1.9 3.6 1 1 3 4 4 4 0 SlyX Rnk_N PF14760.1 EIW79156.1 - 6 7.0 6.7 12 6.0 0.8 2.8 2 0 0 2 2 2 0 Rnk N-terminus Adeno_PIX PF03955.9 EIW79156.1 - 6.7 7.2 12.2 2.9 8.4 2.2 2.6 1 1 1 2 2 2 0 Adenovirus hexon-associated protein (IX) Fib_alpha PF08702.5 EIW79156.1 - 7.4 6.6 15.0 3.8 7.6 3.1 2.3 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.15 EIW79156.1 - 8.2 6.2 30.0 0.93 9.2 3.1 4.1 1 1 3 4 4 4 0 Prefoldin subunit THOC7 PF05615.8 EIW79156.1 - 8.9 6.5 24.6 14 5.8 6.6 2.4 1 1 1 2 2 2 0 Tho complex subunit 7 DUF2968 PF11180.3 EIW79156.1 - 9.9 5.4 21.3 1.7 7.9 4.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) SelR PF01641.13 EIW79157.1 - 1.1e-53 180.1 0.0 1.3e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 SelR domain zf-Mss51 PF13824.1 EIW79157.1 - 0.00092 19.0 1.7 0.015 15.1 0.2 2.8 2 1 1 3 3 3 1 Zinc-finger of mitochondrial splicing suppressor 51 GFA PF04828.9 EIW79157.1 - 0.013 15.4 0.3 0.41 10.6 0.0 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EIW79157.1 - 0.048 13.4 2.7 0.26 11.1 1.8 2.2 1 1 0 1 1 1 0 Double zinc ribbon DUF678 PF05077.7 EIW79157.1 - 0.061 13.3 0.2 1.6 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF678) Yippee-Mis18 PF03226.9 EIW79157.1 - 0.11 12.5 0.5 0.4 10.7 0.3 1.9 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-ribbon_3 PF13248.1 EIW79157.1 - 0.11 11.6 2.1 7 6.0 0.2 2.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EIW79157.1 - 0.15 11.5 2.4 0.69 9.4 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_L37e PF01907.14 EIW79157.1 - 0.81 9.5 5.1 4.5 7.1 1.2 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e DNA_RNApol_7kD PF03604.8 EIW79157.1 - 0.82 9.1 3.8 12 5.4 0.3 2.9 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Pkinase PF00069.20 EIW79158.1 - 2.3e-62 210.5 0.0 3.1e-62 210.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW79158.1 - 2e-33 115.5 0.0 2.8e-33 115.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIW79158.1 - 8e-06 25.0 0.4 0.00015 20.9 0.0 2.7 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EIW79158.1 - 2.8e-05 23.2 0.0 4.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW79158.1 - 0.034 13.8 0.5 0.06 13.0 0.3 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1640 PF07798.6 EIW79159.1 - 3.5e-63 212.8 13.0 4e-63 212.6 9.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) YfbU PF03887.9 EIW79159.1 - 0.013 15.0 2.6 0.017 14.6 0.3 1.9 1 1 1 2 2 2 0 YfbU domain DUF1826 PF08856.6 EIW79159.1 - 0.066 12.9 1.5 0.12 12.1 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1826) ETRAMP PF09716.5 EIW79159.1 - 0.066 13.1 1.8 0.64 10.0 1.3 2.1 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) FlaC_arch PF05377.6 EIW79159.1 - 0.55 10.1 8.9 1.9 8.4 1.1 3.2 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) Phage_lysis PF03245.8 EIW79159.1 - 1 9.3 12.3 0.47 10.4 4.0 2.2 1 1 1 2 2 2 0 Bacteriophage Rz lysis protein DUF4130 PF13566.1 EIW79159.1 - 1.2 8.6 6.8 2.8 7.4 2.0 2.8 2 1 2 4 4 4 0 Domain of unknown function (DUF4130 Baculo_PEP_C PF04513.7 EIW79159.1 - 1.9 8.3 9.4 2.5 7.8 4.3 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Exonuc_VII_L PF02601.10 EIW79159.1 - 2.2 7.4 12.7 2.9 6.9 8.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2115 PF09888.4 EIW79159.1 - 2.3 8.2 10.9 1 9.4 3.3 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) CHD5 PF04420.9 EIW79159.1 - 3.4 7.3 9.6 32 4.1 0.0 2.4 2 1 0 2 2 2 0 CHD5-like protein DivIC PF04977.10 EIW79159.1 - 3.8 7.0 13.6 0.29 10.6 3.9 2.4 1 1 1 2 2 2 0 Septum formation initiator RNA_pol_Rpb5_C PF01191.14 EIW79160.1 - 0.12 11.9 0.0 0.76 9.4 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain Nup35_RRM PF05172.8 EIW79161.1 - 4e-09 36.1 0.0 2.6e-08 33.5 0.0 2.0 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EIW79161.1 - 5e-06 26.1 0.1 8.5e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Ribosomal_L28e PF01778.12 EIW79162.1 - 7.2e-32 110.2 1.7 7.2e-32 110.2 1.2 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 EIW79162.1 - 2.8e-18 65.8 26.1 2.8e-18 65.8 18.1 3.1 1 1 1 2 2 2 1 Mak16 protein C-terminal region Nop14 PF04147.7 EIW79162.1 - 0.038 11.9 19.5 0.045 11.6 13.5 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIF_alpha PF05793.7 EIW79162.1 - 2.9 6.1 21.9 4.1 5.6 15.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) zf-ZPR1 PF03367.8 EIW79163.1 - 8.3e-98 324.1 1.1 4.5e-49 165.7 0.0 3.1 2 1 1 3 3 3 3 ZPR1 zinc-finger domain DZR PF12773.2 EIW79163.1 - 0.017 14.9 5.3 2.2 8.1 0.1 3.2 2 1 0 2 2 2 0 Double zinc ribbon HypA PF01155.14 EIW79163.1 - 0.044 13.4 1.5 6.2 6.5 0.1 2.5 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 EIW79163.1 - 0.21 11.5 1.5 13 5.8 0.0 3.4 3 0 0 3 3 3 0 Zinc ribbon domain ADK_lid PF05191.9 EIW79163.1 - 0.69 9.6 6.5 5.6 6.7 0.0 3.9 4 0 0 4 4 4 0 Adenylate kinase, active site lid zf-ribbon_3 PF13248.1 EIW79163.1 - 0.7 9.1 3.9 13 5.1 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain FA_hydroxylase PF04116.8 EIW79164.1 - 5.8e-19 68.5 9.9 5.8e-19 68.5 6.9 2.4 2 1 0 2 2 2 2 Fatty acid hydroxylase superfamily Phage_P2_GpU PF06995.6 EIW79164.1 - 0.065 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Phage P2 GpU Rcd1 PF04078.8 EIW79165.1 - 7.9e-130 431.3 3.3 9.3e-130 431.1 2.3 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like Mus7 PF09462.5 EIW79166.1 - 6.7e-75 253.1 0.2 1.5e-74 251.9 0.0 1.6 2 0 0 2 2 2 1 Mus7/MMS22 family ComC PF03047.9 EIW79166.1 - 0.3 10.5 1.6 1.7 8.1 0.1 2.4 2 0 0 2 2 2 0 COMC family Cation_efflux PF01545.16 EIW79167.1 - 3.2e-56 190.4 7.2 3.2e-56 190.4 5.0 2.8 2 1 0 2 2 2 1 Cation efflux family PDCD2_C PF04194.8 EIW79168.1 - 7.5e-32 110.1 0.1 7.5e-32 110.1 0.1 1.9 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain DUF1771 PF08590.5 EIW79169.1 - 7.4e-14 51.5 7.0 1.5e-13 50.5 4.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 EIW79169.1 - 2e-06 27.8 0.1 5.6e-06 26.4 0.1 1.8 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.19 EIW79169.1 - 6.2e-06 25.7 8.7 0.013 15.1 1.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) UBA PF00627.26 EIW79169.1 - 0.059 13.2 0.6 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 UBA/TS-N domain zf-C3H1 PF10650.4 EIW79169.1 - 0.2 11.1 2.6 4.6 6.8 0.1 2.4 2 0 0 2 2 2 0 Putative zinc-finger domain PqqD PF05402.7 EIW79169.1 - 0.27 11.2 0.9 0.97 9.4 0.1 2.0 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) IncA PF04156.9 EIW79170.1 - 6.6e-06 25.8 12.5 0.0048 16.5 4.2 2.1 2 0 0 2 2 2 2 IncA protein Reo_sigmaC PF04582.7 EIW79170.1 - 0.00031 20.0 5.7 0.018 14.2 2.3 2.2 2 0 0 2 2 2 1 Reovirus sigma C capsid protein Fez1 PF06818.10 EIW79170.1 - 0.00037 20.5 6.5 0.0044 17.0 0.6 2.1 2 0 0 2 2 2 1 Fez1 FH2 PF02181.18 EIW79170.1 - 0.00054 18.9 5.7 0.033 13.0 0.4 2.2 2 0 0 2 2 2 2 Formin Homology 2 Domain WEMBL PF05701.6 EIW79170.1 - 0.0016 16.9 12.5 0.019 13.4 0.3 2.1 2 0 0 2 2 2 2 Weak chloroplast movement under blue light ATG16 PF08614.6 EIW79170.1 - 0.0016 18.2 13.9 0.13 12.0 5.9 2.3 2 0 0 2 2 2 2 Autophagy protein 16 (ATG16) ADIP PF11559.3 EIW79170.1 - 0.0061 16.4 11.8 0.12 12.2 2.7 2.4 2 0 0 2 2 2 2 Afadin- and alpha -actinin-Binding Spc7 PF08317.6 EIW79170.1 - 0.0078 14.9 12.2 0.11 11.1 3.7 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein DUF342 PF03961.8 EIW79170.1 - 0.0084 14.5 7.3 0.26 9.6 0.9 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF342) APG6 PF04111.7 EIW79170.1 - 0.024 13.7 13.7 0.28 10.1 4.4 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 GAS PF13851.1 EIW79170.1 - 0.025 13.7 14.1 0.41 9.8 3.6 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding IFT57 PF10498.4 EIW79170.1 - 0.026 13.2 8.2 0.096 11.4 2.8 2.1 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 AAA_13 PF13166.1 EIW79170.1 - 0.029 12.8 5.5 0.048 12.1 0.4 2.0 2 0 0 2 2 2 0 AAA domain DUF4201 PF13870.1 EIW79170.1 - 0.06 12.7 10.4 0.21 10.9 2.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF3584 PF12128.3 EIW79170.1 - 0.067 10.5 14.6 0.063 10.6 5.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) TBPIP PF07106.8 EIW79170.1 - 0.077 12.5 10.9 0.35 10.3 2.6 2.4 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF972 PF06156.8 EIW79170.1 - 0.13 12.6 8.0 1.2 9.4 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF972) BssS PF13991.1 EIW79170.1 - 0.13 11.9 1.1 20 5.0 0.0 2.6 1 1 1 2 2 2 0 BssS protein family ArsC PF03960.10 EIW79170.1 - 0.15 12.1 2.0 0.23 11.5 0.3 2.1 2 1 0 2 2 2 0 ArsC family Fib_alpha PF08702.5 EIW79170.1 - 0.24 11.4 9.1 0.11 12.6 2.7 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family SlyX PF04102.7 EIW79170.1 - 0.27 11.6 9.4 15 6.0 0.5 3.4 3 0 0 3 3 3 0 SlyX Atg14 PF10186.4 EIW79170.1 - 0.29 10.0 11.1 0.25 10.2 3.1 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Sec8_exocyst PF04048.9 EIW79170.1 - 0.29 10.7 7.1 0.44 10.1 1.0 2.5 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain DivIVA PF05103.8 EIW79170.1 - 0.32 11.0 13.9 2.3 8.2 3.8 2.5 2 0 0 2 2 2 0 DivIVA protein Occludin_ELL PF07303.8 EIW79170.1 - 0.38 11.5 5.7 4.3 8.1 0.6 2.5 2 0 0 2 2 2 0 Occludin homology domain Uds1 PF15456.1 EIW79170.1 - 0.44 10.5 15.5 0.59 10.1 0.8 2.5 2 0 0 2 2 2 0 Up-regulated During Septation Baculo_PEP_C PF04513.7 EIW79170.1 - 0.67 9.7 7.7 1.5 8.6 2.7 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Seryl_tRNA_N PF02403.17 EIW79170.1 - 0.76 9.8 11.5 4.8 7.2 2.5 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF730 PF05325.6 EIW79170.1 - 1.1 9.0 2.9 2 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF730) Spc24 PF08286.6 EIW79170.1 - 1.2 8.8 15.7 0.33 10.6 0.4 3.2 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 NPV_P10 PF05531.7 EIW79170.1 - 1.3 9.3 8.8 46 4.3 3.3 3.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TMPIT PF07851.8 EIW79170.1 - 1.6 7.7 5.2 16 4.4 1.7 2.1 2 0 0 2 2 2 0 TMPIT-like protein FliJ PF02050.11 EIW79170.1 - 1.8 8.6 14.2 2.7 8.0 3.9 2.6 2 1 0 2 2 2 0 Flagellar FliJ protein COG2 PF06148.6 EIW79170.1 - 1.8 8.4 8.1 6.6 6.6 0.2 2.7 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4140 PF13600.1 EIW79170.1 - 1.9 8.9 12.4 0.39 11.1 0.5 3.2 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) E2R135 PF11570.3 EIW79170.1 - 2.7 8.1 7.9 1.2 9.2 0.9 2.3 2 0 0 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 Laminin_II PF06009.7 EIW79170.1 - 2.7 7.7 9.5 6.2 6.5 3.2 2.3 2 0 0 2 2 2 0 Laminin Domain II Prefoldin_2 PF01920.15 EIW79170.1 - 5 6.9 14.3 0.47 10.2 0.9 3.2 2 1 0 2 2 2 0 Prefoldin subunit Bap31 PF05529.7 EIW79170.1 - 5.1 6.5 6.9 19 4.6 2.1 2.2 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like TPR_MLP1_2 PF07926.7 EIW79170.1 - 6.7 6.4 17.9 2.2 8.0 1.5 2.9 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.14 EIW79170.1 - 7.2 4.3 5.5 7.2 4.3 1.0 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Prominin PF05478.6 EIW79170.1 - 7.5 3.9 6.6 13 3.1 1.3 2.1 2 0 0 2 2 2 0 Prominin Sas10_Utp3 PF04000.10 EIW79170.1 - 7.7 6.7 10.9 34 4.7 0.2 3.3 2 1 0 2 2 2 0 Sas10/Utp3/C1D family Fungal_trans PF04082.13 EIW79171.1 - 3.1e-27 95.0 0.7 6.6e-27 94.0 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW79171.1 - 6.3e-05 22.8 12.2 0.00012 21.9 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ras PF00071.17 EIW79172.1 - 1.9e-47 160.6 0.0 1.4e-46 157.8 0.0 1.9 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EIW79172.1 - 3.1e-13 50.2 0.0 5.3e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW79172.1 - 2.2e-05 23.7 0.0 0.00023 20.4 0.0 2.0 2 0 0 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.5 EIW79172.1 - 0.0012 18.1 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EIW79172.1 - 0.0055 15.8 0.0 0.0076 15.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EIW79172.1 - 0.015 15.2 0.0 0.022 14.6 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase PRK PF00485.13 EIW79172.1 - 0.13 11.8 0.0 0.28 10.7 0.0 1.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Arch_ATPase PF01637.13 EIW79172.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase Clathrin PF00637.15 EIW79173.1 - 2.2e-206 675.7 28.5 5.9e-32 110.2 0.1 7.7 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 EIW79173.1 - 9.4e-37 122.7 1.3 0.00021 21.3 0.0 7.8 7 0 0 7 7 7 7 Clathrin propeller repeat Clathrin_H_link PF13838.1 EIW79173.1 - 6.6e-30 102.7 0.1 2.2e-29 101.1 0.1 2.0 1 0 0 1 1 1 1 Clathrin-H-link Clathrin-link PF09268.5 EIW79173.1 - 7.2e-11 40.8 0.9 1.8e-10 39.5 0.1 2.2 2 0 0 2 2 2 1 Clathrin, heavy-chain linker Coatomer_WDAD PF04053.9 EIW79173.1 - 2.6e-06 26.5 7.3 0.033 13.0 0.0 4.6 4 0 0 4 4 4 3 Coatomer WD associated region TPR_10 PF13374.1 EIW79173.1 - 0.00087 19.1 4.1 0.3 11.0 0.1 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIW79173.1 - 0.0012 19.2 8.5 0.4 11.4 0.1 7.4 8 1 1 9 9 7 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIW79173.1 - 0.0021 17.6 6.4 14 5.5 0.1 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIW79173.1 - 0.0042 16.9 11.4 8.4 6.5 0.1 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIW79173.1 - 0.041 13.8 13.2 0.89 9.5 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 EIW79173.1 - 1.3 9.0 9.8 17 5.4 0.1 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat PQ-loop PF04193.9 EIW79174.1 - 0.00023 20.6 0.1 0.00067 19.1 0.0 1.8 2 0 0 2 2 2 1 PQ loop repeat Zn_clus PF00172.13 EIW79175.1 - 5.3e-05 23.0 8.7 0.00021 21.0 6.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PX PF00787.19 EIW79176.1 - 1.1e-22 79.9 0.8 7.2e-22 77.3 0.0 2.5 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EIW79176.1 - 2.1e-09 37.0 9.5 1.3e-05 24.6 0.7 2.2 2 0 0 2 2 2 2 Vps5 C terminal like BAR PF03114.13 EIW79176.1 - 0.00042 19.9 5.5 0.00043 19.8 0.6 2.2 2 0 0 2 2 2 1 BAR domain DUF4391 PF14335.1 EIW79176.1 - 0.015 14.6 2.4 0.037 13.4 1.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) DUF3510 PF12022.3 EIW79176.1 - 0.051 13.6 0.3 0.15 12.2 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) APP_E2 PF12925.2 EIW79176.1 - 5 6.6 14.3 4.3 6.8 2.2 3.0 3 0 0 3 3 3 0 E2 domain of amyloid precursor protein TRAUB PF08164.7 EIW79177.1 - 1.2e-27 95.8 0.1 3.2e-27 94.4 0.0 1.8 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EIW79177.1 - 2.1e-23 82.9 1.3 2.1e-23 82.9 0.9 2.6 2 1 0 2 2 2 1 Apoptosis antagonizing transcription factor UAA PF08449.6 EIW79179.1 - 9.8e-13 47.6 19.8 1.3e-12 47.2 13.8 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EIW79179.1 - 1.1e-08 34.8 3.8 1.1e-08 34.8 2.6 3.0 2 2 0 2 2 2 1 Triose-phosphate Transporter family CPSase_L_D2 PF02786.12 EIW79180.1 - 3.3e-81 271.6 0.1 6.3e-81 270.6 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EIW79180.1 - 1.6e-66 223.4 0.0 3.8e-66 222.2 0.0 1.7 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EIW79180.1 - 1.7e-36 124.6 0.0 5.1e-36 123.1 0.0 1.9 2 0 0 2 2 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EIW79180.1 - 2.3e-30 104.7 0.0 6e-30 103.3 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EIW79180.1 - 6.6e-29 101.2 0.0 1.4e-28 100.1 0.0 1.6 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 EIW79180.1 - 8.7e-20 71.2 0.1 1.6e-19 70.3 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EIW79180.1 - 5.3e-19 68.1 0.1 6e-18 64.6 0.0 2.4 2 1 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 EIW79180.1 - 5.7e-17 61.1 5.6 1.4e-16 59.8 3.0 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 EIW79180.1 - 2.6e-11 43.3 0.0 5.5e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EIW79180.1 - 1.2e-09 37.7 9.6 3e-06 26.7 0.3 3.0 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp PF02222.17 EIW79180.1 - 2.6e-08 33.4 0.0 5.2e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD PF00529.15 EIW79180.1 - 5.5e-07 29.1 1.8 0.0087 15.4 0.1 2.4 2 0 0 2 2 2 2 HlyD family secretion protein HlyD_3 PF13437.1 EIW79180.1 - 5.4e-06 26.7 0.7 0.028 14.7 0.0 3.0 2 0 0 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 EIW79180.1 - 6.5e-06 26.1 0.0 1.6e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EIW79180.1 - 0.00041 19.8 0.0 0.0015 18.0 0.0 1.9 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GCV_H PF01597.14 EIW79180.1 - 0.00046 19.8 1.2 0.0028 17.3 0.4 2.6 3 1 0 3 3 2 1 Glycine cleavage H-protein NQRA PF05896.6 EIW79180.1 - 0.00051 19.3 1.0 0.0019 17.4 0.3 2.0 2 0 0 2 2 2 1 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_2 PF12700.2 EIW79180.1 - 0.012 14.8 0.8 0.31 10.1 0.0 2.2 1 1 1 2 2 2 0 HlyD family secretion protein RnfC_N PF13375.1 EIW79180.1 - 0.017 14.8 2.9 0.057 13.1 1.2 2.5 2 1 0 2 2 2 0 RnfC Barrel sandwich hybrid domain GARS_A PF01071.14 EIW79180.1 - 0.017 14.6 0.0 0.037 13.5 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NMO PF03060.10 EIW79181.1 - 1.3e-50 172.4 3.3 1.9e-50 171.9 2.3 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EIW79181.1 - 3.9e-08 32.5 0.3 9.5e-05 21.4 0.2 2.1 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EIW79181.1 - 0.00016 20.6 3.6 0.00016 20.6 2.5 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase LSM PF01423.17 EIW79182.1 - 1.7e-14 53.1 0.0 2.4e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 LSM domain Ecl1 PF12855.2 EIW79183.1 - 0.00033 19.8 0.4 0.0007 18.8 0.3 1.6 1 0 0 1 1 1 1 Life-span regulatory factor SHR3_chaperone PF08229.6 EIW79185.1 - 6.7e-33 113.3 0.0 8.2e-33 113.0 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 TrbC PF04956.8 EIW79185.1 - 0.013 15.4 0.3 0.013 15.4 0.2 2.1 1 1 1 2 2 2 0 TrbC/VIRB2 family DUF4149 PF13664.1 EIW79185.1 - 0.71 9.9 5.8 1.6 8.8 1.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) DNA_ligase_A_M PF01068.16 EIW79187.1 - 8.1e-26 90.6 0.0 1.5e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EIW79187.1 - 1.5e-15 57.4 0.0 6.9e-15 55.3 0.0 1.9 2 0 0 2 2 2 1 DNA ligase N terminus DUF3640 PF12342.3 EIW79187.1 - 0.22 11.0 2.4 0.56 9.7 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3640) Actin PF00022.14 EIW79189.1 - 1.5e-38 132.2 0.0 2.2e-38 131.7 0.0 1.2 1 0 0 1 1 1 1 Actin Prenyltrans PF00432.16 EIW79190.1 - 1.6e-29 101.1 7.3 1.1e-09 37.6 0.3 6.1 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 EIW79190.1 - 1.3e-24 86.3 6.7 2.9e-09 36.9 0.2 6.0 2 2 5 7 7 7 5 Prenyltransferase-like Prenyltrans_2 PF13249.1 EIW79190.1 - 2.8e-21 76.0 7.0 5.6e-14 52.5 0.3 5.0 2 2 3 5 5 5 5 Prenyltransferase-like Pec_lyase PF09492.5 EIW79190.1 - 6.8e-06 25.4 0.3 1.8 7.6 0.0 4.7 1 1 3 5 5 5 3 Pectic acid lyase A2M_comp PF07678.9 EIW79190.1 - 0.01 15.0 0.1 0.47 9.6 0.0 3.5 4 1 1 5 5 5 0 A-macroglobulin complement component NIR_SIR PF01077.17 EIW79191.1 - 7.6e-51 171.5 0.1 7.2e-45 152.1 0.0 2.4 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EIW79191.1 - 2.9e-31 106.9 0.0 3.7e-16 58.4 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EIW79191.1 - 6.7e-30 103.9 0.2 1.6e-29 102.7 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin Flavodoxin_NdrI PF07972.6 EIW79191.1 - 0.046 13.6 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 NrdI Flavodoxin like RhoGAP PF00620.22 EIW79192.1 - 7.4e-40 136.0 0.0 1.4e-39 135.1 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.24 EIW79192.1 - 1.1e-12 48.0 0.0 2.2e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 PH domain PX PF00787.19 EIW79192.1 - 9.8e-10 38.2 0.0 2e-09 37.2 0.0 1.5 1 0 0 1 1 1 1 PX domain PH_11 PF15413.1 EIW79192.1 - 7e-08 32.7 0.1 4.1e-07 30.2 0.0 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EIW79192.1 - 0.00024 21.0 0.0 0.00092 19.2 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_7 PF15408.1 EIW79192.1 - 0.083 12.7 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain INT_SG_DDX_CT_C PF15300.1 EIW79193.1 - 0.011 15.2 0.2 0.025 14.0 0.1 1.6 1 1 1 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus RuBisCO_small PF00101.15 EIW79193.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase, small chain SDH_alpha PF03313.10 EIW79194.1 - 4.5e-91 304.7 0.4 6.9e-91 304.1 0.3 1.2 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 EIW79194.1 - 7.7e-56 188.5 0.0 1.5e-55 187.5 0.0 1.5 1 0 0 1 1 1 1 Serine dehydratase beta chain Cyclin_N PF00134.18 EIW79195.1 - 1.2e-10 40.9 0.0 2.5e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain AAA_33 PF13671.1 EIW79196.1 - 2.7e-13 50.0 0.1 1.1e-12 48.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EIW79196.1 - 0.19 10.9 0.0 0.23 10.6 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Tim17 PF02466.14 EIW79197.1 - 4.1e-24 85.0 7.6 5.1e-24 84.7 5.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Velvet PF11754.3 EIW79198.1 - 1.3e-30 106.5 0.0 2.3e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 Velvet factor Cytochrom_C1 PF02167.10 EIW79200.1 - 3.7e-83 278.5 0.0 4.6e-83 278.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EIW79200.1 - 0.0062 16.6 0.0 0.013 15.6 0.0 1.6 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EIW79200.1 - 0.061 14.1 0.2 0.17 12.6 0.1 1.9 1 1 0 1 1 1 0 Cytochrome c SAC3_GANP PF03399.11 EIW79201.1 - 1.9e-59 200.6 2.7 3.2e-59 199.9 1.9 1.4 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EIW79201.1 - 7.5e-06 25.7 0.3 1.9e-05 24.4 0.2 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 PCI PF01399.22 EIW79201.1 - 0.1 12.8 0.3 0.32 11.3 0.0 2.0 2 0 0 2 2 2 0 PCI domain WD40 PF00400.27 EIW79202.1 - 3.7e-19 67.8 3.3 2.5e-06 27.1 0.1 6.4 6 1 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.1 EIW79202.1 - 3.6 7.9 5.9 13 6.1 0.1 4.2 4 1 1 5 5 5 0 PQQ-like domain HAND PF09110.6 EIW79202.1 - 5.9 7.3 8.6 20 5.5 6.0 1.8 1 1 0 1 1 1 0 HAND Aminotran_5 PF00266.14 EIW79203.1 - 6.3e-29 100.8 0.0 8.5e-29 100.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 EIW79203.1 - 0.00016 21.5 1.9 0.0023 17.7 0.2 2.4 2 0 0 2 2 2 1 B12 binding domain Met_gamma_lyase PF06838.6 EIW79203.1 - 0.061 11.6 0.0 0.091 11.0 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase ADH_zinc_N_2 PF13602.1 EIW79204.1 - 1.3e-20 74.5 0.0 2.6e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EIW79204.1 - 2.1e-12 46.7 0.0 5.2e-12 45.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW79204.1 - 0.0089 15.7 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ribosomal_L7Ae PF01248.21 EIW79205.1 - 5e-23 80.4 0.0 5.8e-23 80.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PMM PF03332.8 EIW79207.1 - 9e-106 352.3 0.3 1e-105 352.1 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EIW79207.1 - 0.00013 21.6 0.0 0.0022 17.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EIW79207.1 - 0.0019 17.5 0.0 0.43 9.8 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase TMPIT PF07851.8 EIW79207.1 - 0.019 14.0 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein DNA_pol_B PF00136.16 EIW79208.1 - 3.7e-144 480.9 0.7 5e-144 480.5 0.5 1.1 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EIW79208.1 - 1.2e-85 287.2 0.0 1.9e-85 286.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EIW79208.1 - 1.4e-22 79.4 8.9 3.7e-22 78.0 6.2 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.8 EIW79208.1 - 0.0037 15.9 0.8 0.023 13.3 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral RNase_H_2 PF13482.1 EIW79208.1 - 0.0056 16.5 0.1 0.02 14.6 0.1 1.9 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 EIW79208.1 - 0.035 13.6 0.0 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB C1_1 PF00130.17 EIW79208.1 - 6.5 6.5 8.4 5 6.9 3.0 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Cnd2 PF05786.9 EIW79209.1 - 1.6e-148 496.3 12.0 6.5e-148 494.4 7.9 2.0 1 1 0 1 1 1 1 Condensin complex subunit 2 Atx10homo_assoc PF09759.4 EIW79214.1 - 9.6e-26 89.5 0.7 2.3e-25 88.2 0.2 2.0 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 EIW79214.1 - 0.0028 17.4 0.1 0.11 12.4 0.0 3.4 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Arm_2 PF04826.8 EIW79214.1 - 0.0081 15.2 0.7 0.022 13.8 0.0 2.0 2 0 0 2 2 2 1 Armadillo-like DUF1376 PF07120.6 EIW79214.1 - 0.13 12.4 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1376) BRAP2 PF07576.7 EIW79215.1 - 4.8e-21 74.4 0.0 9.7e-21 73.4 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EIW79215.1 - 2.8e-19 68.9 4.7 2.8e-19 68.9 3.3 2.2 3 0 0 3 3 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EIW79215.1 - 1.5e-08 34.3 9.5 1.5e-08 34.3 6.6 1.9 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIW79215.1 - 1.2e-05 24.8 6.6 3.1e-05 23.5 4.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EIW79215.1 - 6.2e-05 23.0 3.7 0.00017 21.5 2.6 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EIW79215.1 - 0.00013 21.5 6.8 0.00013 21.5 4.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW79215.1 - 0.00053 19.9 8.7 0.00053 19.9 6.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW79215.1 - 0.00072 19.2 6.3 0.00072 19.2 4.4 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EIW79215.1 - 0.013 15.2 4.3 0.033 14.0 3.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RRM_1 PF00076.17 EIW79215.1 - 0.034 13.7 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW79215.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-RING_4 PF14570.1 EIW79215.1 - 0.16 11.5 6.1 0.38 10.3 4.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IncA PF04156.9 EIW79215.1 - 0.57 9.7 19.8 0.86 9.1 13.7 1.2 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EIW79215.1 - 1.2 6.8 10.5 1.8 6.3 7.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TerY-C PF15616.1 EIW79215.1 - 2 8.3 13.7 0.4 10.6 2.1 2.7 1 1 1 2 2 2 0 TerY-C metal binding domain ArfGap PF01412.13 EIW79215.1 - 2.7 7.7 6.7 0.26 11.0 1.0 2.0 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf AAA_13 PF13166.1 EIW79215.1 - 5 5.4 15.0 11 4.3 10.4 1.4 1 1 0 1 1 1 0 AAA domain DUF2968 PF11180.3 EIW79215.1 - 9.4 5.5 18.4 1.5 8.1 5.7 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF2968) Vma12 PF11712.3 EIW79216.1 - 5.3e-12 45.6 0.0 7e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Acetyltransf_1 PF00583.19 EIW79217.1 - 1e-07 31.8 0.0 1.6e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIW79217.1 - 4.4e-07 29.9 0.0 6.7e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIW79217.1 - 0.00019 21.4 0.0 0.00023 21.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIW79217.1 - 0.0025 17.6 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIW79217.1 - 0.0082 15.8 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 EIW79218.1 - 4e-09 36.3 0.0 7.6e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIW79218.1 - 2.2e-06 27.7 0.0 4.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIW79218.1 - 4.8e-06 26.6 0.0 6.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIW79218.1 - 0.0029 17.3 0.0 0.0042 16.8 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EIW79218.1 - 0.082 12.7 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain zf-CCCH PF00642.19 EIW79219.1 - 0.026 14.1 21.6 0.037 13.7 2.8 4.1 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) CENP-F_leu_zip PF10473.4 EIW79219.1 - 0.04 13.7 0.5 0.055 13.3 0.3 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KLRAQ PF10205.4 EIW79219.1 - 0.047 13.7 0.3 0.084 12.9 0.2 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein Packaging_FI PF14000.1 EIW79219.1 - 0.051 13.7 0.2 0.082 13.1 0.1 1.3 1 0 0 1 1 1 0 DNA packaging protein FI MbeD_MobD PF04899.7 EIW79219.1 - 0.14 12.0 1.1 0.59 10.0 0.1 2.2 1 1 1 2 2 2 0 MbeD/MobD like DUF4618 PF15397.1 EIW79219.1 - 0.2 10.9 1.1 0.31 10.3 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) ADIP PF11559.3 EIW79219.1 - 0.22 11.3 1.8 0.38 10.6 1.2 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding WD40 PF00400.27 EIW79220.1 - 7.7e-14 50.9 8.4 4.8e-05 23.0 0.4 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat DnaJ PF00226.26 EIW79221.1 - 6.2e-22 77.1 0.5 9.9e-22 76.4 0.4 1.3 1 0 0 1 1 1 1 DnaJ domain Zip PF02535.17 EIW79221.1 - 1.1 8.2 2.9 1.6 7.6 2.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter EPL1 PF10513.4 EIW79222.1 - 2.1e-16 60.5 2.4 4.2e-16 59.6 0.0 2.5 2 0 0 2 2 2 1 Enhancer of polycomb-like Porphobil_deam PF01379.15 EIW79222.1 - 0.094 11.6 0.1 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Porphobilinogen deaminase, dipyromethane cofactor binding domain SH3_1 PF00018.23 EIW79224.1 - 3.1e-18 64.9 2.9 5.2e-09 35.3 0.1 3.0 2 1 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EIW79224.1 - 1e-12 47.4 2.4 7.1e-06 25.5 0.2 2.6 2 0 0 2 2 2 2 Variant SH3 domain SAM_2 PF07647.12 EIW79224.1 - 1.6e-12 47.0 0.1 3.2e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EIW79224.1 - 2.8e-12 46.6 0.1 4.5e-12 45.9 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_2 PF07653.12 EIW79224.1 - 4.5e-11 42.0 0.2 1.3e-07 30.9 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain RA PF00788.18 EIW79224.1 - 1.2e-10 41.7 0.0 2.5e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_3 PF08239.6 EIW79224.1 - 0.0047 17.0 3.8 0.31 11.2 0.2 3.1 3 0 0 3 3 3 2 Bacterial SH3 domain F-box-like PF12937.2 EIW79225.1 - 0.0011 18.6 0.0 0.0011 18.6 0.0 2.3 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EIW79225.1 - 0.013 15.1 0.0 0.054 13.1 0.0 2.1 1 0 0 1 1 1 0 F-box domain LRR_6 PF13516.1 EIW79225.1 - 2.5 8.4 7.3 46 4.5 0.0 5.4 7 0 0 7 7 7 0 Leucine Rich repeat Pkinase PF00069.20 EIW79226.1 - 1.9e-69 233.7 0.0 2.2e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW79226.1 - 2.1e-32 112.1 0.0 4.8e-32 111.0 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EIW79226.1 - 0.0017 18.1 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW79226.1 - 0.071 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like zf-RanBP PF00641.13 EIW79227.1 - 1.7e-15 55.7 40.1 0.00017 20.5 2.1 4.5 4 0 0 4 4 4 4 Zn-finger in Ran binding protein and others zf-Sec23_Sec24 PF04810.10 EIW79227.1 - 0.011 15.2 13.3 2.5 7.7 0.4 4.9 4 0 0 4 4 4 0 Sec23/Sec24 zinc finger NADH-u_ox-rdase PF10785.4 EIW79228.1 - 1.6e-32 111.5 0.6 2.2e-32 111.1 0.4 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NADH_u_ox_C PF12853.2 EIW79228.1 - 1.3e-15 56.8 0.0 1.9e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit DnaJ PF00226.26 EIW79229.1 - 1.4e-18 66.3 0.8 2.4e-18 65.6 0.1 1.8 2 0 0 2 2 2 1 DnaJ domain TryThrA_C PF12319.3 EIW79229.1 - 0.002 17.3 3.1 0.0026 16.9 2.2 1.2 1 0 0 1 1 1 1 Tryptophan-Threonine-rich plasmodium antigen C terminal DUF643 PF04867.7 EIW79229.1 - 0.0066 16.8 0.1 0.011 16.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF643) Phage_Mu_Gam PF07352.7 EIW79229.1 - 0.037 13.5 2.1 0.059 12.8 1.4 1.2 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein Tho2 PF11262.3 EIW79229.1 - 0.085 11.8 3.1 0.12 11.3 2.2 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4337 PF14235.1 EIW79229.1 - 8.9 6.1 13.0 1 9.1 4.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) OHCU_decarbox PF09349.5 EIW79230.1 - 5.7e-35 120.9 0.0 6.9e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 OHCU decarboxylase GFO_IDH_MocA PF01408.17 EIW79231.1 - 1.8e-20 73.6 0.0 2.7e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Abhydrolase_6 PF12697.2 EIW79232.1 - 3.5e-08 33.6 0.0 4.4e-08 33.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW79232.1 - 4.4e-08 32.9 0.0 4.4e-08 32.9 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW79232.1 - 8.4e-07 28.8 0.0 1.7e-06 27.8 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIW79232.1 - 0.0062 16.3 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Esterase PF00756.15 EIW79232.1 - 0.023 14.1 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Aldo_ket_red PF00248.16 EIW79233.1 - 1.2e-42 145.6 0.3 2.7e-41 141.2 0.1 2.0 2 0 0 2 2 2 2 Aldo/keto reductase family CTP_transf_2 PF01467.21 EIW79234.1 - 0.00019 21.5 0.0 0.00031 20.8 0.0 1.3 1 0 0 1 1 1 1 Cytidylyltransferase Lactamase_B PF00753.22 EIW79235.1 - 3.5e-14 52.8 7.2 7.8e-14 51.7 5.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EIW79235.1 - 1.8e-05 24.4 1.5 2.3e-05 24.0 0.6 1.8 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EIW79235.1 - 0.0016 18.1 0.1 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain peroxidase PF00141.18 EIW79236.1 - 4.8e-47 160.3 0.0 7.4e-47 159.7 0.0 1.2 1 0 0 1 1 1 1 Peroxidase zf-C3HC4 PF00097.20 EIW79237.1 - 2.4e-09 36.6 5.7 5.7e-09 35.4 3.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW79237.1 - 2e-08 34.0 6.9 2e-08 34.0 4.8 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW79237.1 - 2.1e-08 33.8 5.2 2.1e-08 33.8 3.6 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIW79237.1 - 2.2e-08 33.6 3.2 4.6e-08 32.6 2.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW79237.1 - 2.2e-07 30.4 4.7 4.6e-07 29.4 3.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EIW79237.1 - 2.9e-05 23.6 3.0 6.3e-05 22.6 2.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-CCCH PF00642.19 EIW79237.1 - 9.4e-05 21.9 26.7 0.00019 21.0 2.2 3.7 3 1 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-rbx1 PF12678.2 EIW79237.1 - 0.001 19.1 3.5 0.0039 17.2 2.4 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EIW79237.1 - 0.0011 18.7 6.4 0.0029 17.4 4.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING SAGA-Tad1 PF12767.2 EIW79238.1 - 1.1e-34 120.2 0.4 2.9e-34 118.8 0.3 1.6 1 1 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit TAF4 PF05236.9 EIW79238.1 - 0.077 12.2 0.1 0.14 11.4 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family FCH PF00611.18 EIW79239.1 - 1.2e-10 41.3 0.0 4.3e-10 39.6 0.0 2.0 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 EIW79239.1 - 9.3e-10 38.3 0.3 3.1e-09 36.6 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain DEP PF00610.16 EIW79239.1 - 0.0032 17.1 0.0 0.0063 16.2 0.0 1.5 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Nop14 PF04147.7 EIW79239.1 - 0.55 8.0 29.8 0.058 11.3 15.7 2.6 3 0 0 3 3 3 0 Nop14-like family Daxx PF03344.10 EIW79239.1 - 1.4 7.3 27.2 0.19 10.1 12.8 2.2 2 0 0 2 2 2 0 Daxx Family Phe_hydrox_dim PF07976.7 EIW79240.1 - 6.7e-30 103.9 0.0 1.3e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_3 PF01494.14 EIW79240.1 - 6.1e-27 94.5 0.1 8.9e-27 94.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Peptidase_M20 PF01546.23 EIW79241.1 - 2.5e-27 95.6 0.0 3.6e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIW79241.1 - 2.7e-11 43.1 0.0 4.7e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EIW79241.1 - 4.4e-06 26.5 0.0 7.8e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 ATP-sulfurylase PF01747.12 EIW79241.1 - 0.076 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 ATP-sulfurylase GMC_oxred_N PF00732.14 EIW79242.1 - 3.5e-65 220.0 0.0 5.4e-65 219.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIW79242.1 - 3.8e-34 118.0 0.1 7.5e-34 117.0 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EIW79242.1 - 1.6e-05 24.0 0.1 2.4e-05 23.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EIW79242.1 - 0.00092 18.1 0.2 0.086 11.6 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EIW79242.1 - 0.003 17.4 0.2 0.012 15.5 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW79242.1 - 0.0067 15.5 0.1 0.018 14.1 0.0 1.7 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EIW79242.1 - 0.0097 14.8 0.3 0.53 9.1 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EIW79242.1 - 0.078 11.4 0.9 0.13 10.7 0.6 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 EIW79242.1 - 0.11 11.3 0.1 1.1 8.0 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A zf-H2C2_2 PF13465.1 EIW79243.1 - 3.9e-26 90.0 28.6 7.4e-07 29.1 0.3 6.9 7 0 0 7 7 7 4 Zinc-finger double domain zf-C2H2 PF00096.21 EIW79243.1 - 1.4e-17 62.8 39.5 5.2e-06 26.4 0.6 8.3 10 0 0 10 10 10 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW79243.1 - 3.9e-12 45.5 39.1 0.0022 18.1 0.9 8.7 8 0 0 8 8 8 5 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIW79243.1 - 2.2e-06 27.6 6.2 0.012 15.6 0.3 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EIW79243.1 - 1e-05 25.2 22.6 0.013 15.3 0.4 6.2 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EIW79243.1 - 0.0002 21.4 9.9 0.015 15.3 0.8 4.2 4 0 0 4 4 4 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EIW79243.1 - 0.034 14.3 9.7 0.18 12.0 0.6 4.3 4 0 0 4 4 4 0 Zinc-finger of C2H2 type LysM PF01476.15 EIW79244.1 - 2.6e-12 46.4 0.2 1.1e-05 25.2 0.0 2.4 2 0 0 2 2 2 2 LysM domain PNGaseA PF12222.3 EIW79245.1 - 7.4e-71 239.2 9.4 1.2e-70 238.5 6.5 1.2 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A HTH_45 PF14947.1 EIW79245.1 - 0.097 12.4 0.0 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn-helix Ribonucleas_3_3 PF14622.1 EIW79246.1 - 7.6e-09 35.6 0.0 1.3e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 EIW79246.1 - 4.1e-07 30.4 0.0 6.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 EIW79246.1 - 0.00016 22.1 0.0 0.00033 21.0 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease III domain HEV_ORF1 PF02444.11 EIW79248.1 - 0.13 12.4 0.4 0.31 11.2 0.1 1.7 1 1 1 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) MFS_1 PF07690.11 EIW79249.1 - 6.2e-30 104.0 22.7 6.2e-30 104.0 15.7 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1664 PF07889.7 EIW79249.1 - 0.023 14.4 1.5 0.026 14.3 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF962 PF06127.6 EIW79249.1 - 0.039 13.8 0.9 2.5 8.0 0.3 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF962) DUF1049 PF06305.6 EIW79249.1 - 1.5 8.3 4.5 2.6 7.5 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Peptidase_M50B PF13398.1 EIW79250.1 - 1.3e-39 135.6 13.8 1.8e-39 135.2 9.6 1.1 1 0 0 1 1 1 1 Peptidase M50B-like AmiS_UreI PF02293.10 EIW79250.1 - 0.14 11.7 11.1 0.014 15.0 4.1 2.0 2 1 0 2 2 2 0 AmiS/UreI family transporter RRM_1 PF00076.17 EIW79251.1 - 6.4e-32 109.0 1.1 7.1e-16 57.6 0.0 5.2 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW79251.1 - 5.8e-25 87.0 0.2 1.5e-08 34.4 0.0 4.2 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW79251.1 - 1.3e-15 56.9 0.1 0.00035 20.3 0.0 4.3 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.10 EIW79251.1 - 0.011 15.7 0.0 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 Smg-4/UPF3 family CHCH PF06747.8 EIW79252.1 - 3.9e-06 26.6 6.2 5.2e-06 26.2 4.3 1.2 1 0 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 EIW79252.1 - 9e-06 25.7 1.8 1.2e-05 25.3 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) COX6B PF02297.12 EIW79252.1 - 0.00076 19.4 3.9 0.001 19.0 2.7 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb UPF0203 PF05254.7 EIW79252.1 - 0.0038 17.0 2.9 0.0091 15.8 2.0 1.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) Pet191_N PF10203.4 EIW79252.1 - 0.11 12.4 1.8 0.15 12.1 1.2 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EIW79252.1 - 0.78 9.5 5.3 1.1 9.0 0.6 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Brix PF04427.13 EIW79253.1 - 1e-44 152.5 0.0 1.5e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Brix domain TRAP_alpha PF03896.11 EIW79253.1 - 0.65 8.9 4.4 1.1 8.1 3.0 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Daxx PF03344.10 EIW79253.1 - 3.7 5.9 16.7 0.62 8.4 5.8 2.0 2 0 0 2 2 2 0 Daxx Family RR_TM4-6 PF06459.7 EIW79253.1 - 8.6 6.1 13.1 0.21 11.4 1.4 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 EMP24_GP25L PF01105.19 EIW79254.1 - 1.1e-49 168.6 0.4 1.3e-49 168.4 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD ParA PF10609.4 EIW79255.1 - 8.5e-36 121.6 0.0 1.6e-35 120.8 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EIW79255.1 - 1.1e-13 50.9 0.0 1.6e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 EIW79255.1 - 4.1e-05 22.7 1.0 0.0053 15.8 0.1 2.8 2 1 0 2 2 2 1 Anion-transporting ATPase AAA_25 PF13481.1 EIW79255.1 - 0.00023 20.6 0.0 0.00035 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_31 PF13614.1 EIW79255.1 - 0.001 19.0 0.0 0.0031 17.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EIW79255.1 - 0.018 14.2 0.0 1.8 7.7 0.0 2.5 2 1 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF258 PF03193.11 EIW79255.1 - 0.03 13.5 0.0 0.058 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 YhjQ PF06564.7 EIW79255.1 - 0.045 13.1 0.1 0.072 12.4 0.0 1.3 1 0 0 1 1 1 0 YhjQ protein MipZ PF09140.6 EIW79255.1 - 0.081 11.9 0.0 0.39 9.7 0.0 1.9 1 1 0 1 1 1 0 ATPase MipZ AAA_19 PF13245.1 EIW79255.1 - 0.087 12.5 0.3 8.5 6.2 0.0 2.7 2 1 0 2 2 2 0 Part of AAA domain VirE PF05272.6 EIW79255.1 - 0.098 12.1 0.1 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Virulence-associated protein E ArgK PF03308.11 EIW79255.1 - 0.12 11.0 0.1 0.19 10.4 0.1 1.2 1 0 0 1 1 1 0 ArgK protein Symplekin_C PF12295.3 EIW79256.1 - 7.7e-60 201.9 0.5 2.1e-59 200.5 0.3 1.8 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.3 EIW79256.1 - 5.8e-51 173.2 0.0 1.3e-50 172.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) HEAT_2 PF13646.1 EIW79256.1 - 0.00099 19.3 1.1 0.95 9.7 0.0 4.3 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.17 EIW79256.1 - 0.016 15.1 0.3 2.3 8.5 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat SPRR2 PF14820.1 EIW79256.1 - 0.2 11.5 3.4 0.41 10.5 2.4 1.4 1 0 0 1 1 1 0 Small proline-rich 2 Fungal_trans PF04082.13 EIW79257.1 - 5.9e-17 61.3 0.3 9.1e-17 60.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW79257.1 - 4.1e-09 36.2 11.3 7.9e-09 35.2 7.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.14 EIW79258.1 - 5.6e-28 97.1 12.9 6.5e-28 96.9 8.9 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_S19 PF00203.16 EIW79259.1 - 3.1e-33 113.2 0.2 4.8e-33 112.6 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 FliH PF02108.11 EIW79259.1 - 0.0063 16.3 0.0 0.0079 16.0 0.0 1.1 1 0 0 1 1 1 1 Flagellar assembly protein FliH RhoGAP PF00620.22 EIW79260.1 - 8e-34 116.4 0.1 1.5e-33 115.5 0.1 1.4 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EIW79260.1 - 1.4e-27 95.5 36.3 8.6e-12 44.9 6.1 4.6 4 0 0 4 4 4 4 LIM domain DUF914 PF06027.7 EIW79261.1 - 1e-98 330.3 11.1 1.4e-98 329.9 7.7 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 EIW79261.1 - 0.006 15.5 13.3 0.011 14.6 9.2 1.4 1 1 0 1 1 1 1 UAA transporter family DUF2798 PF11391.3 EIW79261.1 - 0.94 9.2 6.8 2.6 7.8 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2798) TFIID_30kDa PF03540.8 EIW79262.1 - 2.7e-27 94.3 0.0 4e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Ribosomal_60s PF00428.14 EIW79262.1 - 0.021 15.2 2.0 1.2 9.5 0.0 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein DUF3464 PF11947.3 EIW79262.1 - 0.043 13.2 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Bromo_TP PF07524.8 EIW79262.1 - 0.11 12.2 0.0 7.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Bromodomain associated Birna_VP4 PF01768.11 EIW79262.1 - 0.13 11.2 0.5 0.73 8.8 0.0 1.9 2 0 0 2 2 2 0 Birnavirus VP4 protein MSA-2c PF12238.3 EIW79262.1 - 5.6 6.5 6.6 11 5.6 3.8 1.8 2 0 0 2 2 2 0 Merozoite surface antigen 2c Fungal_trans PF04082.13 EIW79263.1 - 1.8e-16 59.8 0.3 1.8e-16 59.8 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW79263.1 - 6.3e-05 22.7 15.1 0.00013 21.8 10.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pribosyltran PF00156.22 EIW79264.1 - 2.7e-06 27.1 0.0 4.3e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Mito_carr PF00153.22 EIW79265.1 - 1.2e-73 242.9 4.0 9.2e-24 82.9 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein KduI PF04962.7 EIW79265.1 - 0.052 12.6 0.1 0.22 10.5 0.0 1.8 1 1 0 2 2 2 0 KduI/IolB family SseC PF04888.7 EIW79265.1 - 0.28 10.4 9.2 0.14 11.4 2.8 2.1 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family FAD_binding_3 PF01494.14 EIW79266.1 - 1.6e-18 66.9 0.0 1.6e-16 60.3 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EIW79266.1 - 2e-12 46.6 0.1 4.6e-07 29.0 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW79266.1 - 3.1e-07 30.3 0.9 7.3e-07 29.1 0.6 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIW79266.1 - 7.4e-07 28.4 0.4 0.0035 16.3 0.3 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_binding_2 PF00890.19 EIW79266.1 - 1.3e-06 27.5 0.9 2.3e-06 26.7 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIW79266.1 - 1.1e-05 25.4 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIW79266.1 - 2.1e-05 23.5 0.1 3.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 EIW79266.1 - 8.1e-05 21.2 0.2 0.00014 20.4 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EIW79266.1 - 0.002 18.2 0.0 0.0032 17.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIW79266.1 - 0.0027 16.8 0.2 0.0044 16.1 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EIW79266.1 - 0.0035 17.1 0.4 0.071 12.8 0.1 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 EIW79266.1 - 0.0043 16.1 0.0 0.012 14.7 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 EIW79266.1 - 0.012 16.0 0.0 0.028 14.8 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EIW79266.1 - 0.03 13.4 0.7 0.078 12.0 0.3 1.8 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 EIW79266.1 - 0.03 12.9 0.0 0.24 9.9 0.0 2.2 3 0 0 3 3 3 0 Tryptophan halogenase Rossmann-like PF10727.4 EIW79266.1 - 0.044 13.5 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Rossmann-like domain ApbA PF02558.11 EIW79266.1 - 0.056 12.8 0.2 0.12 11.7 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_10 PF13460.1 EIW79266.1 - 0.078 12.9 0.1 0.15 12.0 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding 3HCDH_N PF02737.13 EIW79266.1 - 0.094 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EIW79267.1 - 1.3e-21 77.0 0.0 2.7e-21 76.0 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIW79267.1 - 8.7e-14 51.1 0.1 2.5e-08 33.2 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW79267.1 - 1.2e-09 38.0 0.1 2.6e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIW79267.1 - 2.1e-06 26.8 0.2 6e-06 25.3 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.19 EIW79267.1 - 3.4e-06 26.4 0.1 0.00047 19.3 0.0 2.6 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EIW79267.1 - 5.9e-06 25.4 0.0 0.0044 15.9 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.22 EIW79267.1 - 1.3e-05 25.5 0.1 0.00082 19.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW79267.1 - 1.4e-05 23.7 0.0 0.00056 18.4 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EIW79267.1 - 2.3e-05 24.3 0.1 4.7e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIW79267.1 - 2.6e-05 23.2 0.0 3.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 EIW79267.1 - 0.00011 21.4 0.1 0.00026 20.1 0.0 1.6 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 EIW79267.1 - 0.00027 20.1 0.3 0.00066 18.8 0.2 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIW79267.1 - 0.0039 17.2 0.0 0.0066 16.5 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rossmann-like PF10727.4 EIW79267.1 - 0.0053 16.4 0.0 0.009 15.7 0.0 1.3 1 0 0 1 1 1 1 Rossmann-like domain 3HCDH_N PF02737.13 EIW79267.1 - 0.0075 15.9 0.0 0.011 15.3 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EIW79267.1 - 0.011 15.5 0.0 0.044 13.5 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding ApbA PF02558.11 EIW79267.1 - 0.042 13.2 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.1 EIW79267.1 - 0.089 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain TrkA_N PF02254.13 EIW79267.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_10 PF13460.1 EIW79267.1 - 0.14 12.0 0.1 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 NADH(P)-binding HD PF01966.17 EIW79268.1 - 6.9e-12 45.4 2.1 1.1e-11 44.7 0.0 2.3 2 1 0 2 2 2 1 HD domain RVT_thumb PF06817.9 EIW79270.1 - 0.023 14.2 0.0 0.063 12.8 0.0 1.8 1 1 1 2 2 2 0 Reverse transcriptase thumb domain PNPOx_C PF10590.4 EIW79270.1 - 0.44 10.0 2.2 0.85 9.1 1.5 1.6 1 1 0 1 1 1 0 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Methyltransf_32 PF13679.1 EIW79272.1 - 0.1 12.3 0.1 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PAT1 PF09770.4 EIW79273.1 - 9.5e-155 516.9 46.2 3.6e-154 515.0 32.1 1.7 1 1 0 1 1 1 1 Topoisomerase II-associated protein PAT1 hDGE_amylase PF14701.1 EIW79274.1 - 7.8e-157 522.4 0.0 1.1e-156 522.0 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EIW79274.1 - 7.8e-116 386.8 0.0 1.2e-115 386.2 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EIW79274.1 - 7.4e-82 274.4 0.0 1e-81 273.9 0.0 1.2 1 0 0 1 1 1 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EIW79274.1 - 2.3e-18 65.8 0.0 5.2e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 EIW79274.1 - 2.2e-05 24.0 0.0 0.00056 19.4 0.0 2.2 2 0 0 2 2 2 1 Alpha amylase, catalytic domain FAD_binding_3 PF01494.14 EIW79275.1 - 1.1e-45 156.3 0.0 2e-24 86.3 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EIW79275.1 - 0.00065 19.6 0.0 0.0018 18.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIW79275.1 - 0.0014 18.5 0.0 0.0033 17.3 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW79275.1 - 0.0027 16.8 0.0 0.0041 16.2 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EIW79275.1 - 0.0094 16.0 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW79275.1 - 0.024 13.5 0.1 0.043 12.7 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EIW79275.1 - 0.087 11.2 0.0 0.14 10.5 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 EIW79275.1 - 0.14 10.9 0.0 0.28 9.9 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EIW79276.1 - 0.0086 14.5 0.1 0.012 14.1 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 EIW79276.1 - 0.03 13.3 0.2 0.044 12.8 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.1 EIW79276.1 - 0.034 14.1 0.0 0.086 12.8 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Zds_C PF08632.5 EIW79277.1 - 3e-22 77.7 0.2 5.6e-22 76.8 0.1 1.4 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term MOZART1 PF12554.3 EIW79278.1 - 3.3e-22 77.6 0.8 4.1e-22 77.3 0.6 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated DUF2962 PF11176.3 EIW79279.1 - 9e-37 126.0 0.8 1.2e-36 125.6 0.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) Pkinase PF00069.20 EIW79280.1 - 9.6e-74 247.8 0.0 1.3e-73 247.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW79280.1 - 1.4e-36 125.8 0.0 2e-36 125.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW79280.1 - 0.0063 15.5 0.0 0.015 14.2 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIW79280.1 - 0.015 15.0 0.0 0.043 13.5 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EIW79280.1 - 0.021 13.9 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EIW79280.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase DNA_ligase_A_M PF01068.16 EIW79281.1 - 2.2e-51 174.0 0.1 4.4e-51 173.1 0.1 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EIW79281.1 - 1.1e-39 136.1 0.0 2.5e-39 134.9 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EIW79281.1 - 6.4e-14 52.1 0.0 3e-13 49.9 0.0 2.2 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EIW79281.1 - 4.1e-13 49.2 0.0 2.5e-08 33.9 0.0 2.9 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain Adaptin_N PF01602.15 EIW79282.1 - 2.8e-141 471.4 8.7 3.3e-141 471.1 6.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EIW79282.1 - 1.2e-17 64.3 0.9 2.1e-17 63.4 0.1 1.9 1 1 1 2 2 2 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EIW79282.1 - 7.7e-06 26.1 5.2 0.28 11.4 0.1 5.0 3 2 1 4 4 4 2 HEAT repeats Cnd1 PF12717.2 EIW79282.1 - 0.0016 18.3 6.0 0.078 12.8 0.9 3.4 2 2 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EIW79282.1 - 0.0028 17.5 4.9 36 4.8 0.0 6.0 6 0 0 6 6 6 0 HEAT repeat TIP120 PF08623.5 EIW79282.1 - 0.0063 16.1 0.9 0.032 13.8 0.2 2.3 1 1 1 2 2 2 1 TATA-binding protein interacting (TIP20) SPG48 PF14764.1 EIW79282.1 - 0.0068 14.9 0.5 0.33 9.3 0.1 2.6 2 1 0 2 2 2 1 AP-5 complex subunit, vesicle trafficking RIX1 PF08167.7 EIW79282.1 - 0.038 13.6 1.3 0.37 10.4 0.0 3.0 3 1 0 3 3 3 0 rRNA processing/ribosome biogenesis NPCBM_assoc PF10633.4 EIW79282.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 NPCBM-associated, NEW3 domain of alpha-galactosidase CN_hydrolase PF00795.17 EIW79283.1 - 3.8e-29 101.3 0.0 5.8e-29 100.7 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EIW79283.1 - 4.7e-25 87.9 0.0 2.1e-24 85.7 0.0 1.9 1 1 0 1 1 1 1 NAD synthase Asn_synthase PF00733.16 EIW79283.1 - 0.012 15.1 0.0 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 Asparagine synthase BPS PF08947.5 EIW79283.1 - 0.039 13.5 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 BPS (Between PH and SH2) EAP30 PF04157.11 EIW79284.1 - 5.6e-54 182.6 0.0 6.3e-54 182.4 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family FIST_C PF10442.4 EIW79284.1 - 0.15 11.9 0.3 0.31 10.9 0.1 1.6 2 1 0 2 2 2 0 FIST C domain SF3b1 PF08920.5 EIW79285.1 - 2.3e-25 89.3 0.7 6.8e-25 87.8 0.5 1.9 1 0 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EIW79285.1 - 3.4e-12 46.4 8.4 4e-05 23.8 0.1 6.6 6 1 1 7 7 7 3 HEAT repeats HEAT PF02985.17 EIW79285.1 - 5.6e-11 41.5 8.2 0.018 15.1 0.0 9.3 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.1 EIW79285.1 - 1.3e-07 31.8 9.8 0.047 14.1 0.0 8.5 7 2 2 9 9 9 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EIW79285.1 - 1.7e-07 31.5 0.9 0.3 11.5 0.0 5.0 5 0 0 5 5 5 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EIW79285.1 - 1.1e-05 23.9 2.4 0.027 12.8 0.0 3.3 2 1 0 3 3 3 2 Adaptin N terminal region NUC173 PF08161.7 EIW79285.1 - 0.00036 19.9 0.4 11 5.3 0.0 4.4 4 1 1 5 5 5 2 NUC173 domain CLASP_N PF12348.3 EIW79285.1 - 0.0023 17.3 3.5 1.2 8.4 0.0 4.0 3 1 1 4 4 4 2 CLASP N terminal Dopey_N PF04118.9 EIW79285.1 - 0.17 10.6 0.2 2.3 6.8 0.0 2.7 3 1 0 3 3 3 0 Dopey, N-terminal Cnd1 PF12717.2 EIW79285.1 - 0.19 11.5 8.1 40 3.9 0.0 5.4 7 0 0 7 7 7 0 non-SMC mitotic condensation complex subunit 1 Methyltransf_2 PF00891.13 EIW79286.1 - 7.9e-33 113.6 0.0 1.2e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EIW79286.1 - 3.2e-05 24.4 0.0 7.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW79286.1 - 0.00013 21.5 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW79286.1 - 0.0002 21.1 0.0 0.00035 20.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW79286.1 - 0.0009 19.6 0.0 0.0018 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW79286.1 - 0.0038 16.6 0.0 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain HTH_IclR PF09339.5 EIW79286.1 - 0.0043 16.6 0.0 0.013 15.0 0.0 1.8 1 0 0 1 1 1 1 IclR helix-turn-helix domain GidB PF02527.10 EIW79286.1 - 0.014 14.5 0.0 0.025 13.7 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_11 PF08241.7 EIW79286.1 - 0.029 14.8 0.0 0.11 13.0 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_16 PF10294.4 EIW79286.1 - 0.084 12.3 0.0 0.22 10.9 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Met_10 PF02475.11 EIW79286.1 - 0.087 12.4 0.1 0.48 9.9 0.0 1.9 1 1 1 2 2 2 0 Met-10+ like-protein DUF1212 PF06738.7 EIW79287.1 - 1e-30 106.6 3.3 1e-30 106.6 2.3 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EIW79287.1 - 4.1e-19 68.7 5.8 4.1e-19 68.7 4.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF3815) ACC_central PF08326.7 EIW79288.1 - 4.6e-208 692.7 0.0 1.2e-207 691.4 0.0 1.6 2 0 0 2 2 2 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EIW79288.1 - 1.5e-164 548.0 0.0 2.2e-164 547.4 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EIW79288.1 - 2.8e-52 177.0 0.0 7.2e-52 175.7 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EIW79288.1 - 5e-25 87.7 0.1 1e-24 86.7 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EIW79288.1 - 1.7e-21 76.1 0.0 6.7e-20 71.0 0.0 3.3 4 0 0 4 4 4 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EIW79288.1 - 2.8e-14 52.4 0.0 5.9e-14 51.4 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EIW79288.1 - 3.3e-11 43.2 0.0 8.5e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EIW79288.1 - 0.00018 20.9 0.0 0.00038 19.9 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.9 EIW79288.1 - 0.00056 19.8 0.0 0.0019 18.1 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp PF02222.17 EIW79288.1 - 0.0094 15.3 0.1 0.02 14.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EIW79288.1 - 0.2 11.0 0.0 0.63 9.4 0.0 1.8 1 1 0 1 1 1 0 RimK-like ATP-grasp domain Peptidase_M20 PF01546.23 EIW79289.1 - 3.4e-22 78.8 0.0 5.2e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIW79289.1 - 1.9e-09 37.2 0.0 3.5e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Dynein_light PF01221.13 EIW79290.1 - 4.9e-37 125.7 1.3 5.4e-37 125.6 0.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.13 EIW79290.1 - 0.052 13.8 0.1 0.06 13.6 0.1 1.3 1 1 0 1 1 1 0 Ground-like domain He_PIG PF05345.7 EIW79291.1 - 5.3e-06 26.3 16.1 1.7e-05 24.7 2.3 4.4 5 0 0 5 5 5 2 Putative Ig domain Protocadherin PF08374.6 EIW79291.1 - 0.0035 17.0 0.2 0.019 14.5 0.0 2.1 2 0 0 2 2 2 1 Protocadherin DUF2207 PF09972.4 EIW79291.1 - 0.033 12.7 0.0 0.052 12.1 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glycophorin_A PF01102.13 EIW79291.1 - 0.048 13.4 0.2 0.048 13.4 0.1 2.2 2 0 0 2 2 2 0 Glycophorin A HEAT_EZ PF13513.1 EIW79292.1 - 1.8e-19 69.5 7.4 8.2e-05 22.9 0.0 10.8 10 2 2 12 12 12 5 HEAT-like repeat HEAT PF02985.17 EIW79292.1 - 1.1e-15 56.2 7.7 0.008 16.1 0.0 8.5 8 0 0 8 8 7 3 HEAT repeat HEAT_2 PF13646.1 EIW79292.1 - 2.8e-13 49.9 4.1 0.0004 20.6 0.0 7.6 6 3 2 8 8 8 4 HEAT repeats IBN_N PF03810.14 EIW79292.1 - 2.6e-08 33.6 2.8 3.5e-08 33.2 0.2 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain Ipi1_N PF12333.3 EIW79292.1 - 6.8e-07 29.1 0.1 1.1 9.2 0.0 6.0 5 1 1 6 6 6 1 Rix1 complex component involved in 60S ribosome maturation Vac14_Fab1_bd PF12755.2 EIW79292.1 - 3.7e-05 24.0 0.0 1.3 9.4 0.0 5.0 5 1 1 6 6 5 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EIW79292.1 - 0.00015 20.2 0.2 0.08 11.2 0.0 3.8 4 0 0 4 4 4 1 Adaptin N terminal region Xpo1 PF08389.7 EIW79292.1 - 0.00084 19.2 1.8 8.5 6.2 0.0 4.8 4 0 0 4 4 4 1 Exportin 1-like protein CLASP_N PF12348.3 EIW79292.1 - 0.0014 18.0 0.5 48 3.2 0.0 5.1 4 2 2 6 6 6 0 CLASP N terminal UME PF08064.8 EIW79292.1 - 0.0027 17.6 0.0 0.14 12.1 0.0 3.5 2 1 1 3 3 3 1 UME (NUC010) domain Cnd1 PF12717.2 EIW79292.1 - 0.07 12.9 0.0 10 5.9 0.0 3.2 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EIW79292.1 - 0.22 11.4 7.5 1.2e+02 2.7 0.0 7.0 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat NUC205 PF08168.6 EIW79293.1 - 0.0066 15.8 0.1 4.4 6.7 0.0 2.6 2 0 0 2 2 2 2 NUC205 domain Toxin_1 PF00087.16 EIW79293.1 - 0.65 10.4 13.1 3.9 7.9 2.0 2.5 2 0 0 2 2 2 0 Snake toxin Sushi_2 PF09014.5 EIW79293.1 - 0.71 9.6 8.0 2.6 7.8 0.7 2.4 2 0 0 2 2 2 0 Beta-2-glycoprotein-1 fifth domain Glyco_hydro_25 PF01183.15 EIW79294.1 - 7.7e-51 172.4 3.2 9e-51 172.2 2.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 BTB PF00651.26 EIW79295.1 - 9e-07 28.8 0.0 4.5e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 BTB/POZ domain DHO_dh PF01180.16 EIW79296.1 - 2.2e-93 312.4 0.0 2.6e-93 312.2 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase FMN_dh PF01070.13 EIW79296.1 - 0.00061 18.7 0.0 0.0051 15.6 0.1 2.2 2 0 0 2 2 2 1 FMN-dependent dehydrogenase PcrB PF01884.12 EIW79296.1 - 0.012 14.8 0.3 3.8 6.6 0.0 2.3 1 1 0 2 2 2 0 PcrB family DeoC PF01791.4 EIW79296.1 - 0.038 13.2 0.0 0.095 11.9 0.0 1.6 2 0 0 2 2 2 0 DeoC/LacD family aldolase Asp_Glu_race PF01177.17 EIW79296.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.5 1 1 0 1 1 1 0 Asp/Glu/Hydantoin racemase FMO-like PF00743.14 EIW79297.1 - 1.4e-39 135.6 0.0 4.9e-29 100.9 0.0 2.2 1 1 1 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EIW79297.1 - 6.3e-15 55.7 0.0 1e-14 55.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW79297.1 - 3.5e-07 29.4 1.1 1.2e-05 24.4 0.1 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EIW79297.1 - 3.3e-06 27.1 0.0 1.1e-05 25.4 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIW79297.1 - 4.7e-05 23.2 0.4 0.0019 17.9 0.0 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EIW79297.1 - 5.9e-05 23.0 0.0 0.00029 20.7 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIW79297.1 - 0.0039 16.3 0.1 0.21 10.6 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Shikimate_DH PF01488.15 EIW79297.1 - 0.085 12.9 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF3692 PF12469.3 EIW79297.1 - 0.12 12.6 0.0 0.59 10.3 0.0 2.1 2 0 0 2 2 2 0 CRISPR-associated protein AlaDh_PNT_C PF01262.16 EIW79297.1 - 0.14 11.7 0.2 0.37 10.3 0.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 EIW79297.1 - 0.14 10.9 0.0 0.57 8.9 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Malic_M PF03949.10 EIW79297.1 - 0.17 11.4 0.0 0.97 8.9 0.0 2.1 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Pyr_redox PF00070.22 EIW79297.1 - 0.28 11.6 0.7 5.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AIP3 PF03915.8 EIW79298.1 - 7.7e-107 357.8 5.3 7.7e-107 357.8 3.7 1.9 2 0 0 2 2 2 1 Actin interacting protein 3 YkyA PF10368.4 EIW79298.1 - 0.0051 16.1 1.2 0.0051 16.1 0.8 2.5 2 0 0 2 2 2 1 Putative cell-wall binding lipoprotein DIRP PF06584.8 EIW79298.1 - 0.011 15.6 0.8 0.59 10.0 0.0 2.9 2 0 0 2 2 2 0 DIRP NPV_P10 PF05531.7 EIW79298.1 - 0.42 10.8 12.0 0.44 10.8 0.9 4.1 3 1 0 3 3 3 0 Nucleopolyhedrovirus P10 protein EcoEI_R_C PF08463.5 EIW79298.1 - 0.66 9.8 8.2 3.3 7.5 0.8 3.1 3 0 0 3 3 3 0 EcoEI R protein C-terminal Zip PF02535.17 EIW79298.1 - 0.73 8.7 3.2 1.3 7.9 2.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1664 PF07889.7 EIW79298.1 - 0.74 9.6 9.8 0.56 10.0 2.3 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) TBPIP PF07106.8 EIW79298.1 - 1.5 8.3 16.1 0.13 11.8 2.6 3.9 3 1 1 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RmuC PF02646.11 EIW79298.1 - 4.9 5.8 12.6 0.41 9.4 0.2 3.3 3 0 0 3 3 3 0 RmuC family Baculo_PEP_C PF04513.7 EIW79298.1 - 5.1 6.9 17.3 7.1 6.4 4.3 4.2 4 2 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus FlaC_arch PF05377.6 EIW79298.1 - 10 6.1 9.4 12 5.9 0.1 4.1 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) Metallophos PF00149.23 EIW79299.1 - 1e-07 31.5 0.2 2.1e-07 30.5 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIW79299.1 - 1.5e-05 24.9 0.4 3.8e-05 23.5 0.3 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ribosomal_L23 PF00276.15 EIW79300.1 - 1.6e-11 43.9 0.0 2.9e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L23 Asp PF00026.18 EIW79302.1 - 1.2e-68 231.7 3.7 1.5e-68 231.4 2.5 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW79302.1 - 6.3e-09 35.9 1.1 6.3e-08 32.7 0.7 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.18 EIW79303.1 - 1.9e-70 237.6 4.4 2.3e-70 237.3 3.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW79303.1 - 2.5e-08 34.0 3.2 2.8e-08 33.9 1.3 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal DHBP_synthase PF00926.14 EIW79305.1 - 5.4e-77 257.4 0.0 6.1e-77 257.2 0.0 1.0 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Mito_carr PF00153.22 EIW79306.1 - 8.1e-33 111.9 6.3 2.6e-19 68.7 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein U1snRNP70_N PF12220.3 EIW79308.1 - 0.0055 17.0 1.2 0.016 15.5 0.8 1.8 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Lant_dehyd_C PF04738.8 EIW79308.1 - 0.093 10.9 0.0 0.17 10.0 0.0 1.3 1 0 0 1 1 1 0 Lantibiotic dehydratase, C terminus Ribosomal_L37ae PF01780.14 EIW79309.1 - 2.9e-38 129.6 11.0 2.9e-38 129.6 7.6 1.3 1 1 1 2 2 2 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EIW79309.1 - 0.0032 17.2 2.3 0.0058 16.4 1.6 1.5 1 0 0 1 1 1 1 Transposase zinc-ribbon domain zf-BED PF02892.10 EIW79309.1 - 0.0082 15.8 4.4 0.085 12.6 0.2 2.4 1 1 1 2 2 2 1 BED zinc finger OrfB_Zn_ribbon PF07282.6 EIW79309.1 - 0.042 13.5 1.1 0.067 12.8 0.7 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF1364 PF07102.7 EIW79309.1 - 0.065 13.1 1.6 0.087 12.7 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1364) zf-Sec23_Sec24 PF04810.10 EIW79309.1 - 0.19 11.3 1.1 3.9 7.1 0.0 2.3 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger C1_1 PF00130.17 EIW79309.1 - 0.24 11.1 2.3 0.48 10.2 1.6 1.5 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.5 EIW79309.1 - 0.34 10.8 2.0 2.4 8.1 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Elf1 PF05129.8 EIW79309.1 - 0.36 10.5 5.1 0.47 10.1 2.6 1.9 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Tnp_zf-ribbon_2 PF13842.1 EIW79309.1 - 0.5 10.8 3.2 1.2 9.5 2.0 1.8 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon A2L_zn_ribbon PF08792.5 EIW79309.1 - 0.57 9.7 5.3 1.3 8.5 0.1 2.3 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-H2C2_2 PF13465.1 EIW79309.1 - 6.6 7.2 7.6 3.6 8.0 0.5 2.4 1 1 1 2 2 2 0 Zinc-finger double domain zf-CCCH PF00642.19 EIW79310.1 - 7.4e-11 41.4 23.1 1e-05 25.0 0.6 5.1 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3H1 PF10650.4 EIW79310.1 - 0.11 12.0 4.7 29 4.2 0.0 3.9 3 0 0 3 3 3 0 Putative zinc-finger domain SNAPc19 PF15497.1 EIW79310.1 - 0.18 11.9 2.6 7.6 6.8 0.0 2.3 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 DUF1712 PF08217.6 EIW79312.1 - 4e-19 68.3 0.0 6.2e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1712) UCH PF00443.24 EIW79313.1 - 1.8e-79 266.6 0.0 3.4e-79 265.7 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW79313.1 - 5.8e-18 65.3 0.0 2.2e-10 40.4 0.0 2.3 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EIW79313.1 - 1.3e-15 57.6 0.1 3.2e-15 56.3 0.0 1.8 1 0 0 1 1 1 1 DUSP domain USP7_C2 PF14533.1 EIW79313.1 - 6e-06 25.8 0.0 1.5e-05 24.5 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin-specific protease C-terminal Zn-ribbon_8 PF09723.5 EIW79313.1 - 0.15 12.0 1.8 2.3 8.2 0.2 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Dak1 PF02733.12 EIW79314.1 - 3.1e-115 384.2 0.9 5.8e-115 383.3 0.6 1.4 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EIW79314.1 - 1.2e-38 132.5 2.8 1.2e-38 132.5 2.0 1.5 2 0 0 2 2 2 1 DAK2 domain Cyto_heme_lyase PF01265.12 EIW79315.1 - 1.9e-63 214.5 0.1 2.2e-63 214.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase WD40 PF00400.27 EIW79316.1 - 7.3e-08 32.0 3.6 0.11 12.4 0.1 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat XRCC4 PF06632.7 EIW79316.1 - 0.18 10.6 1.4 0.29 9.9 1.0 1.2 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 GCFC PF07842.7 EIW79317.1 - 4.4e-76 255.8 9.2 5.7e-76 255.4 6.4 1.1 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EIW79317.1 - 3.4e-13 49.1 5.7 6.5e-13 48.2 1.9 2.4 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EIW79317.1 - 5.6e-05 22.9 0.3 5.6e-05 22.9 0.2 3.4 2 2 1 3 3 3 1 DExH-box splicing factor binding site Atg14 PF10186.4 EIW79317.1 - 0.054 12.4 1.4 0.094 11.6 1.0 1.4 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 eIF-3c_N PF05470.7 EIW79317.1 - 0.099 10.7 0.2 0.15 10.0 0.2 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus FUSC PF04632.7 EIW79317.1 - 0.13 10.7 0.6 0.2 10.0 0.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family AAA PF00004.24 EIW79318.1 - 1.6e-42 144.8 0.0 2.8e-42 144.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIW79318.1 - 1.5e-07 31.2 0.2 1.9e-06 27.6 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIW79318.1 - 2.4e-07 30.9 0.1 3.4e-05 23.9 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EIW79318.1 - 5.8e-06 26.4 0.0 0.0013 18.9 0.0 2.6 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 EIW79318.1 - 6.4e-06 26.1 0.0 2.7e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EIW79318.1 - 9.1e-06 24.8 0.0 1.8e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EIW79318.1 - 2.5e-05 23.9 0.6 0.00028 20.5 0.6 2.3 1 1 1 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 EIW79318.1 - 0.00035 21.3 0.3 0.001 19.8 0.1 2.1 2 1 0 2 2 1 1 AAA domain Zeta_toxin PF06414.7 EIW79318.1 - 0.0014 17.7 1.7 0.017 14.2 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin DUF815 PF05673.8 EIW79318.1 - 0.0015 17.4 0.0 0.003 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EIW79318.1 - 0.0019 18.0 0.1 0.0065 16.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EIW79318.1 - 0.0019 17.3 0.0 0.0043 16.2 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EIW79318.1 - 0.0026 17.2 0.1 0.005 16.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EIW79318.1 - 0.0029 16.3 0.0 0.0052 15.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_18 PF13238.1 EIW79318.1 - 0.003 17.8 0.1 0.025 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIW79318.1 - 0.0037 17.4 0.0 0.0076 16.4 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.1 EIW79318.1 - 0.0047 16.8 0.0 0.0099 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EIW79318.1 - 0.0053 16.7 0.0 0.013 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EIW79318.1 - 0.0083 15.5 0.3 0.041 13.2 0.1 2.1 1 1 1 2 2 2 1 AAA domain PhoH PF02562.11 EIW79318.1 - 0.0092 15.2 0.1 0.02 14.1 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein Sigma54_activat PF00158.21 EIW79318.1 - 0.01 15.3 0.0 0.04 13.3 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EIW79318.1 - 0.01 15.4 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EIW79318.1 - 0.011 15.3 0.2 0.025 14.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EIW79318.1 - 0.016 15.5 0.8 4.9 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 EIW79318.1 - 0.018 14.8 0.0 0.045 13.5 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NACHT PF05729.7 EIW79318.1 - 0.042 13.5 0.0 0.17 11.5 0.0 1.9 1 1 1 2 2 2 0 NACHT domain AAA_30 PF13604.1 EIW79318.1 - 0.054 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EIW79318.1 - 0.057 12.9 0.6 0.43 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EIW79318.1 - 0.058 12.4 0.9 0.16 11.0 0.0 2.1 3 0 0 3 3 3 0 KaiC Parvo_NS1 PF01057.12 EIW79318.1 - 0.059 12.2 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 EIW79318.1 - 0.089 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activ_2 PF14532.1 EIW79318.1 - 0.12 12.4 0.0 0.35 10.9 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain Sec1 PF00995.18 EIW79319.1 - 3.6e-137 458.3 0.0 4.5e-137 458.0 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Polysacc_deac_1 PF01522.16 EIW79320.1 - 1.2e-27 95.9 0.0 2.4e-27 95.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase FGGY_N PF00370.16 EIW79321.1 - 8.3e-26 90.7 0.0 1.2e-15 57.5 0.0 2.6 2 1 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EIW79321.1 - 2.6e-21 76.1 0.1 1e-20 74.2 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain PseudoU_synth_1 PF01416.15 EIW79322.1 - 3.2e-20 72.5 0.0 2.5e-09 37.4 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase SUZ PF12752.2 EIW79323.1 - 2.4e-15 56.7 1.4 2.4e-15 56.7 1.0 3.4 3 0 0 3 3 3 1 SUZ domain R3H PF01424.17 EIW79323.1 - 0.00015 21.3 0.0 0.00036 20.1 0.0 1.5 1 0 0 1 1 1 1 R3H domain Aa_trans PF01490.13 EIW79324.1 - 1.4e-85 287.2 29.0 1.7e-85 286.9 20.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EIW79324.1 - 6.5e-06 25.2 20.5 6.5e-06 25.2 14.2 1.8 2 0 0 2 2 2 1 Tryptophan/tyrosine permease family DUF202 PF02656.10 EIW79326.1 - 3.6e-05 23.8 1.8 3.6e-05 23.8 1.2 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF202) DUF3262 PF11660.3 EIW79326.1 - 2 8.5 8.3 0.14 12.2 2.3 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3262) DUF4231 PF14015.1 EIW79326.1 - 5.4 7.0 7.1 1.7 8.6 1.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) MTHFR PF02219.12 EIW79327.1 - 1e-107 359.5 0.0 1.5e-107 358.9 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ELMO_CED12 PF04727.8 EIW79328.1 - 2.8e-26 92.0 0.2 4.6e-26 91.3 0.1 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family DUF3361 PF11841.3 EIW79328.1 - 1.7e-12 47.3 0.0 1.3e-10 41.1 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) Acyl-CoA_ox_N PF14749.1 EIW79328.1 - 0.0019 18.4 0.0 1.2 9.4 0.0 2.7 2 0 0 2 2 2 2 Acyl-coenzyme A oxidase N-terminal GST_N_3 PF13417.1 EIW79330.1 - 3.7e-13 49.4 0.0 8.9e-13 48.2 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW79330.1 - 4.4e-11 42.6 0.0 8.8e-11 41.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW79330.1 - 3.4e-06 26.8 0.0 8e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW79330.1 - 0.0034 17.5 0.0 0.011 15.8 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW79330.1 - 0.054 13.4 0.0 0.14 12.1 0.0 1.8 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RCC1_2 PF13540.1 EIW79331.1 - 1.9e-07 30.5 16.9 4.6e-05 22.9 0.2 5.1 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EIW79331.1 - 2.7e-07 30.7 3.8 0.32 11.2 0.0 4.6 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 EIW79331.1 - 0.00024 20.7 1.0 0.0004 20.0 0.7 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW79331.1 - 0.16 11.6 1.1 0.29 10.8 0.7 1.5 1 0 0 1 1 1 0 F-box domain Colicin-DNase PF12639.2 EIW79332.1 - 0.81 9.9 7.9 0.057 13.6 2.0 1.8 2 0 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin zf-C3HC4 PF00097.20 EIW79334.1 - 3e-05 23.5 11.5 3e-05 23.5 8.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW79334.1 - 0.0013 18.4 12.8 0.0013 18.4 8.9 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIW79334.1 - 0.002 17.7 8.9 0.0062 16.1 6.2 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW79334.1 - 0.0022 17.9 13.2 0.0053 16.7 9.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW79334.1 - 0.0034 17.0 9.1 0.0034 17.0 6.3 2.1 1 1 1 2 2 2 1 zinc-RING finger domain K-box PF01486.12 EIW79334.1 - 0.05 13.4 0.9 0.11 12.2 0.6 1.5 1 0 0 1 1 1 0 K-box region zf-C3HC4_4 PF15227.1 EIW79334.1 - 1.3 8.9 14.6 10 6.0 9.9 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Actin PF00022.14 EIW79335.1 - 1.2e-29 102.9 0.0 1.4e-12 46.7 0.0 3.1 3 0 0 3 3 3 3 Actin MreB_Mbl PF06723.8 EIW79335.1 - 2.7e-05 22.9 0.1 0.00026 19.6 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FAT PF02259.18 EIW79336.1 - 1.4e-117 392.6 3.7 1.4e-117 392.6 2.6 1.8 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EIW79336.1 - 2.3e-56 190.9 0.3 4.9e-56 189.8 0.2 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.3 EIW79336.1 - 8.1e-48 162.3 4.9 1e-47 162.0 0.2 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) Rapamycin_bind PF08771.6 EIW79336.1 - 5.1e-40 135.6 0.0 3.2e-39 133.0 0.0 2.6 1 0 0 1 1 1 1 Rapamycin binding domain HEAT_2 PF13646.1 EIW79336.1 - 1.1e-17 64.0 10.3 0.00039 20.6 0.0 9.5 5 2 4 9 9 8 5 HEAT repeats FATC PF02260.15 EIW79336.1 - 3.7e-15 55.0 0.3 3.7e-15 55.0 0.2 2.0 2 0 0 2 2 2 1 FATC domain HEAT PF02985.17 EIW79336.1 - 9e-11 40.9 16.4 0.0091 16.0 0.0 11.1 11 0 0 11 11 10 2 HEAT repeat CLASP_N PF12348.3 EIW79336.1 - 5.8e-07 29.0 4.1 0.15 11.3 0.0 6.3 6 1 1 7 7 7 1 CLASP N terminal HEAT_EZ PF13513.1 EIW79336.1 - 4e-05 23.9 0.2 4e-05 23.9 0.1 11.7 14 2 3 17 17 15 1 HEAT-like repeat TPR_19 PF14559.1 EIW79336.1 - 0.00012 22.3 0.2 0.35 11.2 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIW79336.1 - 0.014 15.1 4.0 1.2 9.0 0.1 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIW79336.1 - 0.023 15.3 6.6 0.21 12.3 0.3 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EIW79336.1 - 0.032 14.3 0.4 9.2 6.4 0.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EIW79336.1 - 0.063 12.9 4.2 1.8 8.2 0.3 4.1 4 0 0 4 4 4 0 TPR repeat AP2 PF00847.15 EIW79336.1 - 0.084 13.0 0.2 0.34 11.1 0.1 2.1 1 0 0 1 1 1 0 AP2 domain TPR_2 PF07719.12 EIW79336.1 - 0.15 12.0 9.0 4.9 7.3 0.4 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIW79336.1 - 0.62 10.8 6.0 3.6 8.4 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIW79336.1 - 6.5 6.5 7.8 8.9 6.1 0.3 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M20 PF01546.23 EIW79338.1 - 5.8e-09 35.7 0.1 9e-09 35.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIW79338.1 - 1.1e-07 31.5 0.0 2.4e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain DnaJ-X PF14308.1 EIW79339.1 - 1.4e-58 197.5 0.3 1.7e-58 197.2 0.2 1.1 1 0 0 1 1 1 1 X-domain of DnaJ-containing DUF4378 PF14309.1 EIW79339.1 - 0.023 14.7 0.2 0.023 14.7 0.2 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4378) FTCD PF02971.9 EIW79339.1 - 0.13 11.8 0.0 0.36 10.4 0.0 1.7 1 0 0 1 1 1 0 Formiminotransferase domain DnaJ PF00226.26 EIW79340.1 - 8.7e-25 86.2 2.8 1.6e-24 85.3 2.0 1.5 1 0 0 1 1 1 1 DnaJ domain Carn_acyltransf PF00755.15 EIW79342.1 - 2.7e-138 461.6 0.0 3.3e-138 461.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase DUF1768 PF08719.6 EIW79343.1 - 8.4e-33 113.3 0.0 1.1e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) PARP PF00644.15 EIW79344.1 - 8.9e-21 74.2 4.5 2.6e-18 66.2 0.7 3.0 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain PARP PF00644.15 EIW79345.1 - 2.2e-08 33.7 12.6 5.3e-08 32.5 0.4 4.0 3 2 0 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain Spt20 PF12090.3 EIW79345.1 - 0.051 12.9 3.3 0.08 12.2 2.3 1.4 1 0 0 1 1 1 0 Spt20 family DUF2116 PF09889.4 EIW79345.1 - 0.069 12.9 0.5 0.069 12.9 0.3 3.2 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) SpoIIIAH PF12685.2 EIW79345.1 - 0.13 11.7 5.4 0.23 10.9 3.8 1.5 1 1 0 1 1 1 0 SpoIIIAH-like protein TraT PF05818.7 EIW79345.1 - 1 8.7 6.7 0.34 10.2 0.1 2.4 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein CNH PF00780.17 EIW79346.1 - 3.1e-80 269.5 0.0 6.8e-80 268.4 0.0 1.5 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 EIW79346.1 - 1.2e-40 138.5 0.0 2.2e-40 137.6 0.0 1.4 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EIW79346.1 - 5e-33 114.4 0.0 7.4e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EIW79346.1 - 1.5e-12 47.0 0.0 3.1e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PH PF00169.24 EIW79346.1 - 0.037 14.2 0.0 0.11 12.6 0.0 1.9 2 0 0 2 2 2 0 PH domain PH_10 PF15411.1 EIW79346.1 - 0.13 12.4 0.0 0.41 10.8 0.0 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain Amidase PF01425.16 EIW79347.1 - 1.6e-84 284.3 0.0 1.7e-83 280.9 0.0 1.9 1 1 0 1 1 1 1 Amidase PI3_PI4_kinase PF00454.22 EIW79348.1 - 4.2e-46 157.3 0.0 8.4e-46 156.3 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase TAN PF11640.3 EIW79348.1 - 1e-24 87.0 0.2 1e-24 87.0 0.1 3.4 4 0 0 4 4 4 1 Telomere-length maintenance and DNA damage repair FATC PF02260.15 EIW79348.1 - 0.00019 20.7 0.1 0.00048 19.4 0.1 1.7 1 0 0 1 1 1 1 FATC domain Pkinase PF00069.20 EIW79349.1 - 5.3e-72 242.0 0.1 4e-71 239.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW79349.1 - 1.4e-49 168.5 0.4 6.3e-49 166.3 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 EIW79349.1 - 1.8e-21 76.3 0.0 1.8e-21 76.3 0.0 2.5 2 0 0 2 2 2 1 P21-Rho-binding domain Kinase-like PF14531.1 EIW79349.1 - 0.00015 20.8 0.0 0.00032 19.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW79349.1 - 0.09 12.4 10.5 0.11 12.2 0.2 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family DSHCT PF08148.7 EIW79349.1 - 0.2 10.9 0.0 0.2 10.9 0.0 1.9 2 0 0 2 2 2 0 DSHCT (NUC185) domain DUF4407 PF14362.1 EIW79349.1 - 1.8 7.4 10.5 3 6.7 7.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) F-box-like PF12937.2 EIW79351.1 - 2.5e-12 46.3 3.2 6.2e-12 45.0 2.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW79351.1 - 1.4e-05 24.5 2.2 3.5e-05 23.3 1.5 1.7 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 EIW79351.1 - 0.0038 16.9 0.1 0.012 15.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like domain Coatomer_E PF04733.9 EIW79352.1 - 7.5e-30 104.1 0.0 2.3e-29 102.5 0.0 1.6 1 1 0 1 1 1 1 Coatomer epsilon subunit TPR_16 PF13432.1 EIW79352.1 - 0.0022 18.6 13.2 0.077 13.7 1.9 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIW79352.1 - 0.0037 16.8 3.2 4.2 7.0 0.0 3.9 3 1 0 4 4 4 1 TPR repeat TPR_9 PF13371.1 EIW79352.1 - 0.0094 15.7 3.0 0.043 13.6 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIW79352.1 - 0.019 15.2 11.0 1.1 9.6 0.1 3.9 3 2 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EIW79352.1 - 0.023 14.8 0.1 5 7.3 0.0 3.2 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EIW79352.1 - 0.22 12.2 13.0 11 6.9 0.3 5.1 3 2 2 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIW79352.1 - 0.27 11.2 7.4 8.6 6.5 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIW79352.1 - 2.4 8.8 5.6 28 5.4 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat An_peroxidase PF03098.10 EIW79353.1 - 2.3e-77 260.5 0.0 2.5e-75 253.8 0.0 2.2 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EIW79353.1 - 1.3e-07 30.5 0.0 3.2e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EIW79354.1 - 5.3e-10 38.8 5.5 5.3e-10 38.8 3.8 2.4 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 EIW79354.1 - 0.049 13.3 0.2 0.15 11.7 0.1 1.9 1 0 0 1 1 1 0 F-box-like domain LRR_4 PF12799.2 EIW79354.1 - 0.21 11.2 5.4 0.2 11.3 0.3 3.4 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EIW79355.1 - 2.6e-11 43.0 2.4 8.4e-11 41.4 1.6 1.9 1 0 0 1 1 1 1 F-box-like TRAM_LAG1_CLN8 PF03798.11 EIW79356.1 - 4.2e-31 108.0 22.5 4.2e-31 108.0 15.6 2.1 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EIW79356.1 - 1.7e-12 46.6 0.3 4.4e-12 45.3 0.2 1.8 1 0 0 1 1 1 1 TRAM1-like protein F-box-like PF12937.2 EIW79357.1 - 7.2e-11 41.6 1.9 2.1e-10 40.1 1.3 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW79357.1 - 0.49 10.1 9.2 3 7.6 3.7 3.5 2 1 0 2 2 2 0 F-box domain LRR_1 PF00560.28 EIW79357.1 - 0.79 9.9 4.8 6.1 7.2 0.1 4.8 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 EIW79357.1 - 0.8 10.1 4.5 16 6.2 0.4 5.2 6 1 1 7 7 7 0 Leucine rich repeat PX PF00787.19 EIW79358.1 - 1.5e-16 60.1 0.1 2.7e-16 59.3 0.1 1.4 1 0 0 1 1 1 1 PX domain Rep_4 PF05797.6 EIW79358.1 - 0.071 11.8 0.5 0.21 10.2 0.1 1.8 2 0 0 2 2 2 0 Yeast trans-acting factor (REP1/REP2) PMT PF02366.13 EIW79359.1 - 6.6e-73 245.0 18.8 6.6e-73 245.0 13.0 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EIW79359.1 - 4.1e-12 46.0 6.2 5.2e-12 45.6 3.8 1.5 1 1 0 1 1 1 1 MIR domain Pkinase PF00069.20 EIW79360.1 - 8.1e-59 198.8 0.1 7.2e-39 133.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW79360.1 - 3.2e-25 88.6 0.6 6e-19 68.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIW79360.1 - 0.00022 20.2 1.1 0.0013 17.7 0.1 2.5 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 EIW79360.1 - 0.00037 19.6 0.1 0.0022 17.0 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EIW79360.1 - 0.0023 16.8 0.1 0.0039 16.0 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EIW79360.1 - 0.0072 16.0 0.2 0.26 10.9 0.1 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIW79360.1 - 0.0085 15.4 2.9 0.093 12.0 0.0 2.3 2 0 0 2 2 2 1 RIO1 family Orbi_NS1 PF01718.11 EIW79360.1 - 0.036 12.1 0.1 0.056 11.4 0.1 1.2 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein Pkinase_C PF00433.19 EIW79360.1 - 0.054 14.0 0.3 0.054 14.0 0.2 2.0 2 0 0 2 2 2 0 Protein kinase C terminal domain Pox_ser-thr_kin PF05445.6 EIW79360.1 - 0.14 10.8 0.1 0.23 10.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase WD40 PF00400.27 EIW79361.1 - 9.4e-56 183.8 7.6 3.4e-10 39.3 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EIW79361.1 - 7e-13 47.6 1.1 1.5e-12 46.5 0.8 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 EIW79361.1 - 9e-05 21.7 0.0 1.2 8.2 0.0 3.2 2 1 1 3 3 3 3 Neuroblastoma-amplified sequence, N terminal Glyco_hydro_18 PF00704.23 EIW79362.1 - 6.9e-12 45.4 6.1 1.3e-11 44.5 4.2 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF4537 PF15057.1 EIW79362.1 - 0.081 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) SnoaL_2 PF12680.2 EIW79363.1 - 8.9e-06 26.0 0.0 1.1e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_3 PF13474.1 EIW79363.1 - 0.024 14.6 0.0 0.037 14.0 0.0 1.3 1 0 0 1 1 1 0 SnoaL-like domain Methyltransf_23 PF13489.1 EIW79365.1 - 4.8e-24 84.8 0.0 1e-23 83.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW79365.1 - 1.9e-19 69.9 0.0 3.5e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW79365.1 - 2.7e-15 56.8 0.3 5.1e-15 56.0 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW79365.1 - 1.5e-14 54.2 0.0 3e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW79365.1 - 9.9e-14 51.1 0.0 1.6e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW79365.1 - 6.2e-08 32.9 0.0 1.3e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EIW79365.1 - 1.3e-07 30.9 0.0 1.9e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EIW79365.1 - 1.7e-07 31.2 1.5 1.7e-07 31.2 1.1 2.1 2 2 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EIW79365.1 - 2.1e-06 27.0 0.0 3.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_9 PF08003.6 EIW79365.1 - 7.4e-05 21.5 0.0 0.00013 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.13 EIW79365.1 - 0.00056 19.1 0.0 0.00082 18.5 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EIW79365.1 - 0.00077 18.8 0.1 0.0016 17.8 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 EIW79365.1 - 0.014 15.0 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EIW79365.1 - 0.045 13.1 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW AdoMet_MTase PF07757.8 EIW79365.1 - 0.091 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase NodS PF05401.6 EIW79365.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) E1-E2_ATPase PF00122.15 EIW79366.1 - 1.5e-48 164.8 0.8 1.5e-48 164.8 0.5 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EIW79366.1 - 4.5e-37 128.5 6.7 1e-36 127.3 4.7 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EIW79366.1 - 1e-28 99.2 0.0 5.8e-14 51.9 0.0 2.8 2 0 0 2 2 2 2 Heavy-metal-associated domain HAD PF12710.2 EIW79366.1 - 8.9e-12 45.5 0.1 3.4e-11 43.6 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIW79366.1 - 0.002 17.7 0.3 0.068 12.7 0.0 2.2 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase DUF1656 PF07869.7 EIW79366.1 - 0.41 10.4 12.4 0.28 10.9 2.3 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1656) Couple_hipA PF13657.1 EIW79367.1 - 0.03 14.5 0.0 0.076 13.3 0.0 1.6 1 1 1 2 2 2 0 HipA N-terminal domain Spectrin PF00435.16 EIW79367.1 - 0.069 13.4 1.5 0.32 11.2 0.8 2.2 2 1 0 2 2 2 0 Spectrin repeat IncA PF04156.9 EIW79367.1 - 0.12 12.0 0.8 0.21 11.1 0.5 1.4 1 0 0 1 1 1 0 IncA protein Rnk_N PF14760.1 EIW79367.1 - 8 6.6 8.4 20 5.3 0.4 3.5 2 1 1 3 3 3 0 Rnk N-terminus PH_10 PF15411.1 EIW79368.1 - 2.2e-27 95.5 0.0 4.5e-27 94.5 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain zf-RING_2 PF13639.1 EIW79368.1 - 2.2e-06 27.3 1.5 4.6e-06 26.3 1.1 1.6 1 0 0 1 1 1 1 Ring finger domain VWA_3 PF13768.1 EIW79368.1 - 0.00019 21.1 0.1 0.00019 21.1 0.1 3.2 3 1 0 3 3 3 1 von Willebrand factor type A domain zf-RING_5 PF14634.1 EIW79368.1 - 0.00089 18.9 0.4 0.0021 17.7 0.3 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIW79368.1 - 0.003 17.1 0.8 0.0053 16.3 0.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EIW79368.1 - 0.0085 16.1 0.2 0.071 13.2 0.1 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EIW79368.1 - 0.083 12.9 0.6 0.2 11.6 0.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DOPA_dioxygen PF08883.6 EIW79369.1 - 2.2e-23 82.2 0.0 2.7e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family HET PF06985.6 EIW79370.1 - 1.5e-21 76.9 2.5 7.1e-18 65.1 0.1 2.2 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) PALP PF00291.20 EIW79371.1 - 3e-58 197.4 0.7 3.5e-58 197.2 0.5 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF4185 PF13810.1 EIW79373.1 - 2.7e-05 23.2 0.3 6.3e-05 22.0 0.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4185) Glyco_hydro_18 PF00704.23 EIW79374.1 - 2.3e-10 40.4 0.7 3e-10 40.0 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_18 PF00704.23 EIW79375.1 - 9.9e-16 58.1 5.8 1.3e-15 57.7 4.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.3 EIW79375.1 - 0.078 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) DUF1180 PF06679.7 EIW79377.1 - 0.15 11.9 0.8 0.27 11.0 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Pkinase PF00069.20 EIW79378.1 - 6.3e-66 222.1 0.0 9.9e-66 221.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW79378.1 - 6.9e-53 179.3 0.0 1e-52 178.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase C1_1 PF00130.17 EIW79378.1 - 7.2e-06 25.6 5.5 1.2e-05 24.9 3.8 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CH PF00307.26 EIW79378.1 - 1.4e-05 25.0 0.0 4.3e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Calponin homology (CH) domain Kinase-like PF14531.1 EIW79378.1 - 0.0013 17.7 0.0 0.042 12.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like PHD PF00628.24 EIW79378.1 - 0.031 13.9 5.3 0.065 12.9 3.7 1.5 1 0 0 1 1 1 0 PHD-finger C1_3 PF07649.7 EIW79378.1 - 0.034 14.1 3.5 0.06 13.3 2.4 1.4 1 0 0 1 1 1 0 C1-like domain IL34 PF15036.1 EIW79378.1 - 0.042 13.4 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 Interleukin 34 RIO1 PF01163.17 EIW79378.1 - 0.17 11.1 0.0 0.33 10.2 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Tnp_zf-ribbon_2 PF13842.1 EIW79378.1 - 0.27 11.6 6.0 0.56 10.6 4.2 1.6 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Prok-RING_1 PF14446.1 EIW79378.1 - 0.3 10.8 4.6 0.61 9.8 3.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_2 PF03107.11 EIW79378.1 - 1.2 9.2 2.5 2.1 8.5 1.7 1.4 1 0 0 1 1 1 0 C1 domain Ank_2 PF12796.2 EIW79380.1 - 1e-13 51.4 0.0 2.8e-08 33.9 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EIW79380.1 - 1.4e-13 49.8 1.3 1.2e-06 28.0 0.1 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EIW79380.1 - 4.9e-12 45.6 0.1 5.8e-06 26.3 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIW79380.1 - 1.3e-11 44.6 0.2 9.5e-08 32.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIW79380.1 - 1.1e-10 40.6 0.1 8.6e-05 22.4 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat KilA-N PF04383.8 EIW79380.1 - 0.00043 19.8 0.1 0.0081 15.7 0.1 2.4 1 1 0 1 1 1 1 KilA-N domain Filament PF00038.16 EIW79380.1 - 0.057 12.8 1.1 0.1 12.0 0.8 1.3 1 0 0 1 1 1 0 Intermediate filament protein HNH_2 PF13391.1 EIW79382.1 - 5.2e-05 22.9 0.3 0.00012 21.8 0.2 1.6 1 0 0 1 1 1 1 HNH endonuclease Glyco_hydro_18 PF00704.23 EIW79383.1 - 4.2e-13 49.4 3.9 5.4e-13 49.0 2.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LEA_6 PF10714.4 EIW79383.1 - 0.42 10.4 3.0 0.42 10.4 0.1 2.3 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 Glyco_hydro_18 PF00704.23 EIW79384.1 - 1.9e-09 37.4 1.8 2.4e-09 37.1 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 BTB PF00651.26 EIW79385.1 - 8.5e-08 32.1 0.0 1.7e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF676 PF05057.9 EIW79386.1 - 4.4e-41 140.5 0.0 6.7e-41 139.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EIW79386.1 - 8.6e-06 25.4 0.0 1.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EIW79386.1 - 0.0041 16.7 0.0 0.0065 16.0 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EIW79386.1 - 0.0074 16.0 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DOPA_dioxygen PF08883.6 EIW79387.1 - 3.9e-32 110.4 0.0 4.7e-32 110.1 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family DEAD PF00270.24 EIW79388.1 - 2.4e-10 40.1 0.0 3.9e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EIW79388.1 - 0.0084 15.9 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Vps5 PF09325.5 EIW79392.1 - 1.9e-61 207.3 6.8 2.7e-61 206.8 4.7 1.2 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EIW79392.1 - 2.4e-25 88.4 2.0 2.9e-25 88.2 0.1 2.1 3 0 0 3 3 3 1 PX domain BAR PF03114.13 EIW79392.1 - 9.3e-06 25.3 5.9 1.8e-05 24.3 4.1 1.4 1 1 0 1 1 1 1 BAR domain BAR_3_WASP_bdg PF10456.4 EIW79392.1 - 0.056 12.7 1.3 0.21 10.8 0.9 1.9 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein Arfaptin PF06456.8 EIW79392.1 - 0.11 11.8 6.7 0.12 11.6 3.2 2.1 2 1 0 2 2 2 0 Arfaptin-like domain DWNN PF08783.6 EIW79393.1 - 9.6e-29 99.1 0.2 9.6e-29 99.1 0.2 2.0 2 0 0 2 2 2 1 DWNN domain zf-CCHC_2 PF13696.1 EIW79393.1 - 1.9e-07 30.4 2.5 5.1e-07 29.0 1.8 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EIW79393.1 - 2.6e-05 23.9 2.5 2.6e-05 23.9 1.7 2.4 2 0 0 2 2 2 1 Zinc knuckle GRP PF07172.6 EIW79393.1 - 0.0012 19.3 2.2 0.0012 19.3 1.5 2.1 2 0 0 2 2 2 1 Glycine rich protein family zf-CCHC_3 PF13917.1 EIW79393.1 - 0.0012 18.5 0.1 0.0038 16.9 0.1 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-C3HC4_2 PF13923.1 EIW79393.1 - 0.004 17.1 9.4 0.004 17.1 6.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHC_5 PF14787.1 EIW79393.1 - 0.011 15.2 1.0 0.011 15.2 0.7 2.4 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger OmpH PF03938.9 EIW79393.1 - 0.016 15.1 21.4 0.022 14.6 12.4 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) zf-C3HC4_3 PF13920.1 EIW79393.1 - 0.016 14.8 6.3 0.016 14.8 4.3 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) UPF0147 PF03685.8 EIW79393.1 - 0.086 12.7 0.6 0.21 11.4 0.4 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Trm112p PF03966.11 EIW79393.1 - 0.16 12.3 1.6 0.2 12.0 0.1 2.0 2 0 0 2 2 2 0 Trm112p-like protein zf-C3HC4 PF00097.20 EIW79393.1 - 1.2 8.8 10.5 2.5 7.8 7.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-H2C2_2 PF13465.1 EIW79393.1 - 2.3 8.6 6.8 1.9 8.9 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double domain zf-RING_2 PF13639.1 EIW79393.1 - 2.6 7.9 14.1 0.059 13.2 5.2 1.7 2 0 0 2 2 2 0 Ring finger domain ERG4_ERG24 PF01222.12 EIW79394.1 - 5.9e-128 427.0 28.1 6.7e-128 426.8 19.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.9 EIW79394.1 - 0.003 17.7 0.1 0.012 15.8 0.1 2.0 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF1295 PF06966.7 EIW79394.1 - 0.0094 15.2 11.7 0.02 14.1 8.1 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) TMEM95 PF15203.1 EIW79394.1 - 0.14 11.5 0.2 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 TMEM95 family DnaJ PF00226.26 EIW79395.1 - 5.9e-26 89.9 0.2 1.1e-25 89.0 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.6 EIW79395.1 - 8.6e-13 48.4 4.3 1e-11 45.0 3.0 2.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1977) DUF566 PF04484.7 EIW79395.1 - 5.5 6.4 9.7 9.3 5.6 6.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) DNA_binding_1 PF01035.15 EIW79396.1 - 2e-15 56.2 0.0 2.5e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain F-box-like PF12937.2 EIW79397.1 - 4.3e-07 29.5 0.1 8.3e-07 28.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW79397.1 - 4.3e-07 29.4 0.1 7.6e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 F-box domain MIT PF04212.13 EIW79397.1 - 0.00035 20.3 0.3 0.0025 17.6 0.0 2.4 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.12 EIW79397.1 - 0.033 14.1 0.1 0.11 12.5 0.1 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIW79397.1 - 0.047 13.3 0.1 0.12 12.0 0.1 1.6 1 0 0 1 1 1 0 TPR repeat Ndc1_Nup PF09531.5 EIW79397.1 - 5.5 5.2 6.8 8 4.7 4.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup WD40 PF00400.27 EIW79398.1 - 1.1e-11 44.1 2.9 2 8.4 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Clr2 PF10383.4 EIW79400.1 - 0.0029 17.5 0.0 0.026 14.5 0.0 2.5 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 YokU PF14122.1 EIW79400.1 - 0.063 13.0 0.2 6.4 6.5 0.0 2.7 3 0 0 3 3 3 0 YokU-like protein zf-C2H2_3 PF13878.1 EIW79400.1 - 0.09 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 zinc-finger of acetyl-transferase ESCO KAR9 PF08580.5 EIW79401.1 - 3.6e-05 22.2 40.3 3.6e-05 22.2 28.0 2.5 1 1 0 2 2 2 1 Yeast cortical protein KAR9 NPV_P10 PF05531.7 EIW79401.1 - 0.0019 18.4 0.7 5.3 7.3 0.0 3.7 3 1 0 3 3 3 2 Nucleopolyhedrovirus P10 protein GAS2 PF02187.12 EIW79401.1 - 0.0022 17.7 0.3 0.0053 16.4 0.2 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain IncA PF04156.9 EIW79401.1 - 1.1 8.8 4.1 0.77 9.3 0.6 2.1 1 1 1 2 2 2 0 IncA protein TPR_19 PF14559.1 EIW79402.1 - 6e-10 39.3 0.0 0.00081 19.6 0.0 4.0 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIW79402.1 - 6.2e-09 35.7 6.5 0.0014 19.0 0.1 5.6 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIW79402.1 - 1.2e-08 34.4 0.4 4.6e-05 22.9 0.1 3.3 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EIW79402.1 - 3.7e-06 26.4 0.3 0.017 14.9 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIW79402.1 - 2.7e-05 23.6 0.6 0.03 14.0 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIW79402.1 - 6e-05 22.9 5.5 0.016 15.1 0.2 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.9 EIW79402.1 - 7.1e-05 22.8 7.0 0.022 15.1 0.0 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIW79402.1 - 0.00011 22.7 5.9 0.0017 18.9 0.1 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIW79402.1 - 0.00045 19.7 0.0 0.0057 16.2 0.0 2.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EIW79402.1 - 0.0036 17.3 0.3 0.51 10.6 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIW79402.1 - 0.013 15.8 1.2 0.2 12.1 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF410 PF04190.8 EIW79402.1 - 0.034 13.6 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF410) Apc3 PF12895.2 EIW79402.1 - 0.039 14.0 0.3 12 6.1 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EIW79402.1 - 0.047 13.6 6.5 0.26 11.2 0.4 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_21 PF09976.4 EIW79402.1 - 1.8 8.4 6.4 8.6 6.3 0.3 3.3 2 2 0 2 2 2 0 Tetratricopeptide repeat F-box-like PF12937.2 EIW79405.1 - 8.4e-08 31.8 1.6 8.4e-08 31.8 1.1 2.5 3 0 0 3 3 3 1 F-box-like F-box-like PF12937.2 EIW79406.1 - 1.2e-07 31.3 3.4 2.9e-07 30.1 2.4 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIW79406.1 - 0.013 15.1 0.7 0.76 9.4 0.0 3.5 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW79406.1 - 0.027 14.2 1.0 10 5.9 0.0 3.8 2 1 0 3 3 3 0 Leucine rich repeat Mak16 PF04874.9 EIW79406.1 - 0.95 9.5 9.9 1.7 8.8 6.9 1.3 1 0 0 1 1 1 0 Mak16 protein C-terminal region RXT2_N PF08595.6 EIW79406.1 - 3.5 7.4 5.8 5.7 6.7 4.0 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal LRR_7 PF13504.1 EIW79406.1 - 3.6 8.2 7.1 37 5.1 0.0 5.3 6 0 0 6 6 6 0 Leucine rich repeat Dicty_REP PF05086.7 EIW79406.1 - 3.8 5.1 4.4 5.5 4.6 3.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Nucleoplasmin PF03066.10 EIW79406.1 - 5 6.6 9.7 9 5.8 6.7 1.3 1 0 0 1 1 1 0 Nucleoplasmin CTD_bind PF04818.8 EIW79407.1 - 0.0092 16.1 0.0 0.025 14.7 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase II-binding domain. F-box-like PF12937.2 EIW79408.1 - 0.023 14.4 1.0 0.023 14.4 0.7 2.7 3 0 0 3 3 3 0 F-box-like ubiquitin PF00240.18 EIW79409.1 - 6.5e-35 118.3 0.7 1.4e-34 117.2 0.5 1.6 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_S27 PF01599.14 EIW79409.1 - 4.2e-27 93.7 1.9 9e-27 92.6 1.3 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EIW79409.1 - 7.5e-20 70.4 0.7 1.5e-19 69.4 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EIW79409.1 - 1.1e-05 25.5 0.4 4.9e-05 23.5 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EIW79409.1 - 0.00021 21.0 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EIW79409.1 - 0.00029 20.6 0.5 0.00065 19.5 0.4 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2207 PF09972.4 EIW79409.1 - 0.0036 15.9 0.7 0.0041 15.7 0.5 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF2407 PF10302.4 EIW79409.1 - 0.0055 16.8 0.8 0.0074 16.4 0.6 1.2 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF971 PF06155.7 EIW79409.1 - 0.021 15.2 0.0 0.038 14.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF971) IBR PF01485.16 EIW79409.1 - 0.045 13.6 0.7 0.071 12.9 0.5 1.4 1 0 0 1 1 1 0 IBR domain Plexin_cytopl PF08337.7 EIW79409.1 - 0.046 12.0 3.2 0.42 8.8 0.2 2.0 1 1 0 2 2 2 0 Plexin cytoplasmic RasGAP domain Stig1 PF04885.8 EIW79409.1 - 0.07 13.3 0.1 0.11 12.6 0.1 1.4 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 DUF2870 PF11069.3 EIW79409.1 - 0.13 12.3 1.3 0.15 12.1 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2870) Rep_fac_C PF08542.6 EIW79410.1 - 2.5e-21 75.4 0.0 6.7e-21 74.0 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.24 EIW79410.1 - 5.9e-18 65.3 0.0 1.2e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EIW79410.1 - 7.6e-17 61.4 0.0 7.7e-15 54.9 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EIW79410.1 - 1.4e-09 37.2 0.0 4.4e-07 28.9 0.0 2.4 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EIW79410.1 - 7e-08 32.4 0.1 4e-07 29.9 0.0 2.1 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 EIW79410.1 - 1.2e-06 28.7 0.9 0.046 13.8 0.0 2.4 1 1 1 2 2 2 2 AAA domain DUF815 PF05673.8 EIW79410.1 - 4.4e-06 25.8 0.0 6.6e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EIW79410.1 - 8.6e-06 25.4 0.0 1.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EIW79410.1 - 2.3e-05 24.0 0.4 0.00023 20.8 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EIW79410.1 - 2.3e-05 24.0 0.2 7.1e-05 22.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 EIW79410.1 - 2.4e-05 23.9 0.1 4.6e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.1 EIW79410.1 - 3.5e-05 23.8 0.0 0.00019 21.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EIW79410.1 - 4.7e-05 23.1 0.1 0.00041 20.0 0.0 2.5 3 1 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EIW79410.1 - 0.00014 21.4 0.0 0.00025 20.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIW79410.1 - 0.00014 20.9 0.0 0.00044 19.3 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DEAD PF00270.24 EIW79410.1 - 0.0009 18.7 0.3 0.0099 15.3 0.2 2.1 1 1 1 2 2 2 1 DEAD/DEAH box helicase IstB_IS21 PF01695.12 EIW79410.1 - 0.0019 17.6 0.0 0.0048 16.3 0.0 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.1 EIW79410.1 - 0.0038 16.8 0.1 0.0086 15.6 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EIW79410.1 - 0.0046 16.3 0.0 0.013 14.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EIW79410.1 - 0.0065 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Arch_ATPase PF01637.13 EIW79410.1 - 0.0067 16.1 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 Archaeal ATPase ResIII PF04851.10 EIW79410.1 - 0.015 15.1 0.1 0.082 12.7 0.1 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PIF1 PF05970.9 EIW79410.1 - 0.02 13.8 0.2 0.67 8.8 0.1 2.2 1 1 1 2 2 2 0 PIF1-like helicase AAA_28 PF13521.1 EIW79410.1 - 0.022 14.7 0.1 0.045 13.6 0.1 1.6 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EIW79410.1 - 0.03 13.3 0.0 0.12 11.2 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 EIW79410.1 - 0.031 15.0 0.0 0.06 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain SNF2_N PF00176.18 EIW79410.1 - 0.035 12.9 0.2 0.097 11.4 0.1 1.9 1 1 0 1 1 1 0 SNF2 family N-terminal domain Mg_chelatase PF01078.16 EIW79410.1 - 0.036 13.2 0.0 0.26 10.3 0.0 2.0 1 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_10 PF12846.2 EIW79410.1 - 0.039 13.4 0.3 4 6.7 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain Bac_DnaA PF00308.13 EIW79410.1 - 0.047 13.3 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein T2SE PF00437.15 EIW79410.1 - 0.053 12.4 0.0 0.15 10.9 0.0 1.6 1 1 0 1 1 1 0 Type II/IV secretion system protein Methyltransf_31 PF13847.1 EIW79410.1 - 0.07 12.7 0.3 0.19 11.2 0.2 1.8 2 1 0 2 2 1 0 Methyltransferase domain Sigma54_activat PF00158.21 EIW79410.1 - 0.074 12.5 0.0 7.2 6.0 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain CobA_CobO_BtuR PF02572.10 EIW79410.1 - 0.081 12.5 0.3 3.3 7.2 0.1 2.4 1 1 1 2 2 2 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP TPR_6 PF13174.1 EIW79410.1 - 0.083 13.3 1.1 2 9.0 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat MobB PF03205.9 EIW79410.1 - 0.092 12.4 0.0 0.22 11.2 0.0 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EIW79410.1 - 0.16 12.2 0.3 0.45 10.8 0.2 1.7 1 1 0 1 1 1 0 AAA domain Zw10 PF06248.8 EIW79411.1 - 7.3e-16 57.4 0.0 2.8e-09 35.7 0.0 2.3 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 EIW79411.1 - 4.6e-08 32.5 0.0 9.6e-08 31.5 0.0 1.4 1 0 0 1 1 1 1 Retrograde transport protein Dsl1 C terminal MFS_1 PF07690.11 EIW79412.1 - 6.5e-28 97.4 30.5 6.5e-28 97.4 21.1 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EIW79412.1 - 3.5e-08 32.2 20.2 0.025 12.9 9.9 3.1 1 1 2 3 3 3 3 MFS/sugar transport protein TRI12 PF06609.8 EIW79412.1 - 1.4e-05 23.5 0.6 1.4e-05 23.5 0.4 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MBOAT PF03062.14 EIW79413.1 - 3e-29 102.1 15.6 3e-29 102.1 10.8 2.9 2 2 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EIW79413.1 - 1.1e-05 25.4 3.5 3.6e-05 23.7 2.4 1.9 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family dCMP_cyt_deam_1 PF00383.17 EIW79414.1 - 3e-21 74.9 0.2 4.1e-21 74.5 0.2 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EIW79414.1 - 9.6e-05 22.2 1.9 0.0015 18.4 1.3 2.2 1 1 0 1 1 1 1 Bd3614-like deaminase Peptidase_S9_N PF02897.10 EIW79415.1 - 1.2e-86 290.9 6.4 1.5e-86 290.5 4.5 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 EIW79415.1 - 2.2e-56 190.4 0.0 4.1e-56 189.5 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EIW79415.1 - 0.04 13.5 0.3 0.27 10.7 0.2 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold RED_N PF07808.8 EIW79416.1 - 2.7e-14 52.9 5.7 2.7e-14 52.9 3.9 2.5 3 0 0 3 3 3 1 RED-like protein N-terminal region MMgT PF10270.4 EIW79417.1 - 2.7e-15 56.7 0.0 3e-15 56.5 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter MFS_1 PF07690.11 EIW79418.1 - 1e-28 100.0 26.1 1e-28 100.0 18.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW79418.1 - 8e-08 31.2 0.3 8e-08 31.2 0.2 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EIW79418.1 - 6.8e-06 24.5 0.6 1.1e-05 23.8 0.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PBP PF01161.15 EIW79419.1 - 3.4e-30 104.8 0.5 4.1e-30 104.5 0.3 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein SNF2_N PF00176.18 EIW79421.1 - 3.9e-21 75.1 0.2 2.4e-13 49.5 0.0 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain DNA_methylase PF00145.12 EIW79421.1 - 5e-14 52.1 0.0 3.9e-13 49.2 0.0 2.3 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase DUF348 PF03990.9 EIW79421.1 - 0.01 15.3 1.9 0.24 10.9 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF348) zf-RING_5 PF14634.1 EIW79421.1 - 5 6.9 18.8 0.014 15.1 5.2 2.5 3 0 0 3 3 3 0 zinc-RING finger domain Cript PF10235.4 EIW79422.1 - 1.3e-21 76.6 7.0 1.3e-21 76.6 4.8 1.6 1 1 1 2 2 2 1 Microtubule-associated protein CRIPT zf-dskA_traR PF01258.12 EIW79422.1 - 0.057 13.1 8.4 0.89 9.3 0.1 3.8 3 1 1 4 4 4 0 Prokaryotic dksA/traR C4-type zinc finger stn_TNFRSF12A PF12191.3 EIW79422.1 - 0.16 11.9 0.8 0.26 11.3 0.6 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain zinc_ribbon_2 PF13240.1 EIW79422.1 - 0.28 10.7 13.9 8.2 6.0 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EIW79422.1 - 0.45 9.7 9.4 2.3 7.5 2.4 3.1 3 0 0 3 3 3 0 zinc-ribbon domain Gin PF10764.4 EIW79422.1 - 0.48 10.1 8.6 0.9 9.2 0.0 2.9 2 1 0 2 2 2 0 Inhibitor of sigma-G Gin XPA_N PF01286.13 EIW79422.1 - 0.58 9.8 0.0 0.58 9.8 0.0 3.6 4 0 0 4 4 4 0 XPA protein N-terminal DUF2039 PF10217.4 EIW79422.1 - 1.2 9.1 15.2 0.45 10.5 6.5 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) DUF1272 PF06906.6 EIW79422.1 - 1.5 8.7 7.7 1.4 8.7 2.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Prok-RING_1 PF14446.1 EIW79422.1 - 1.6 8.5 13.8 2.6 7.8 0.0 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 DUF4428 PF14471.1 EIW79422.1 - 2 8.2 9.8 1.1 9.0 0.1 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4428) HypA PF01155.14 EIW79422.1 - 2.6 7.7 5.7 2.4 7.8 1.9 2.1 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family FYVE_2 PF02318.11 EIW79422.1 - 4.5 7.2 7.0 3.6 7.5 2.4 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger zf-C3HC4_3 PF13920.1 EIW79422.1 - 7.3 6.3 17.3 52 3.6 7.1 3.0 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Methyltransf_16 PF10294.4 EIW79424.1 - 7.4e-20 71.1 0.0 1e-19 70.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EIW79424.1 - 6.4e-06 26.7 0.0 1e-05 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW79424.1 - 0.0001 21.9 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW79424.1 - 0.0016 17.8 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EIW79424.1 - 0.0016 18.1 0.0 0.0025 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW79424.1 - 0.0051 17.2 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW79424.1 - 0.029 14.8 0.0 0.057 13.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 EIW79424.1 - 0.035 13.2 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Met_10 PF02475.11 EIW79424.1 - 0.071 12.6 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein PCMT PF01135.14 EIW79424.1 - 0.15 11.5 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) WD40 PF00400.27 EIW79425.1 - 2e-42 141.5 14.2 3.4e-09 36.2 0.0 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat HARP PF07443.8 EIW79425.1 - 0.085 12.2 0.1 19 4.7 0.0 2.7 2 0 0 2 2 2 0 HepA-related protein (HARP) HEAT_2 PF13646.1 EIW79426.1 - 0.028 14.6 0.5 6.6 7.0 0.0 2.8 3 0 0 3 3 3 0 HEAT repeats SIR2 PF02146.12 EIW79427.1 - 7.4e-29 100.7 0.0 9.6e-29 100.3 0.0 1.1 1 0 0 1 1 1 1 Sir2 family AT_hook PF02178.14 EIW79428.1 - 0.18 11.5 4.1 0.47 10.2 2.9 1.7 1 0 0 1 1 1 0 AT hook motif DUF4451 PF14616.1 EIW79429.1 - 7.4e-06 25.7 6.7 0.0032 17.2 0.1 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4451) zf-CW PF07496.10 EIW79429.1 - 1.6 8.4 8.2 4.4 7.0 0.2 2.8 2 0 0 2 2 2 0 CW-type Zinc Finger Yippee-Mis18 PF03226.9 EIW79429.1 - 8.1 6.5 6.5 4.3 7.4 2.5 2.0 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PGM_PMM_I PF02878.11 EIW79432.1 - 1e-38 131.9 0.0 1.6e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EIW79432.1 - 2.6e-26 91.8 0.0 1.6e-25 89.2 0.0 2.2 3 0 0 3 3 3 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EIW79432.1 - 6.8e-14 52.0 0.0 2.7e-13 50.1 0.0 2.0 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EIW79432.1 - 3.2e-07 30.2 0.0 8.3e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Carb_kinase PF01256.12 EIW79433.1 - 5e-51 173.3 0.0 7.4e-40 136.7 0.0 2.1 1 1 1 2 2 2 2 Carbohydrate kinase Ribonuc_P_40 PF08584.6 EIW79434.1 - 6.2e-22 77.9 0.0 1.5e-21 76.6 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit ATG16 PF08614.6 EIW79436.1 - 0.038 13.8 3.3 0.084 12.6 2.3 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) SNF2_N PF00176.18 EIW79437.1 - 3.7e-15 55.5 0.0 6.6e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW79437.1 - 4.2e-09 36.1 0.0 2.8e-08 33.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Med10 PF09748.4 EIW79437.1 - 0.011 15.5 0.1 0.078 12.8 0.0 2.3 2 0 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex Reo_sigma1 PF01664.11 EIW79437.1 - 0.1 11.6 0.0 0.18 10.8 0.0 1.4 1 0 0 1 1 1 0 Reovirus viral attachment protein sigma 1 Abhydrolase_6 PF12697.2 EIW79439.1 - 1.4e-20 74.1 0.0 1.7e-20 73.8 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW79439.1 - 8.6e-15 54.9 0.0 1.3e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW79439.1 - 7.9e-07 28.9 0.0 2.7e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EIW79439.1 - 0.017 15.3 0.0 0.022 14.9 0.0 1.4 1 1 0 1 1 1 0 Thioesterase domain Hydrolase_4 PF12146.3 EIW79439.1 - 0.089 12.6 0.0 0.23 11.3 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase DUF1057 PF06342.7 EIW79439.1 - 0.13 11.0 0.0 0.46 9.2 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Nop53 PF07767.6 EIW79440.1 - 1.3e-73 248.2 13.0 1.7e-73 247.9 9.0 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) WD40 PF00400.27 EIW79441.1 - 1.1e-49 164.5 11.4 6e-08 32.2 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat PD40 PF07676.7 EIW79441.1 - 3.1e-08 33.1 0.1 1.1 8.9 0.0 6.2 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EIW79441.1 - 2.3e-05 24.2 0.0 0.073 12.7 0.0 3.2 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 EIW79441.1 - 0.0002 20.8 0.1 0.015 14.7 0.0 2.8 1 1 1 2 2 2 2 Lipoprotein LpqB beta-propeller domain Apc4_WD40 PF12894.2 EIW79441.1 - 0.00031 20.1 0.0 1.6 8.3 0.0 4.0 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Proteasome_A_N PF10584.4 EIW79441.1 - 0.0011 18.2 1.2 13 5.1 0.1 5.5 6 0 0 6 6 6 1 Proteasome subunit A N-terminal signature Nucleoporin_N PF08801.6 EIW79441.1 - 0.017 13.9 2.4 0.25 10.0 1.2 2.4 2 1 1 3 3 3 0 Nup133 N terminal like PQQ_3 PF13570.1 EIW79441.1 - 0.02 15.1 2.7 9.6 6.6 0.0 3.7 2 2 2 4 4 4 0 PQQ-like domain Nup160 PF11715.3 EIW79441.1 - 0.025 12.7 1.8 4.2 5.3 0.0 3.2 1 1 2 4 4 4 0 Nucleoporin Nup120/160 Neurokinin_B PF03823.9 EIW79442.1 - 1.5 8.5 3.8 3.1 7.6 0.3 2.4 2 0 0 2 2 2 0 Neurokinin B Chorion_2 PF03964.10 EIW79443.1 - 0.051 14.1 8.3 0.13 12.8 5.7 1.7 1 0 0 1 1 1 0 Chorion family 2 RAP1 PF07218.6 EIW79443.1 - 2.5 6.1 6.0 3.4 5.6 4.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) CDK2AP PF09806.4 EIW79443.1 - 9.2 6.4 8.6 7.9 6.6 4.9 1.5 1 1 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Glyco_transf_90 PF05686.7 EIW79444.1 - 2.8e-17 62.5 1.0 1.3e-14 53.7 0.3 3.5 3 1 0 3 3 3 2 Glycosyl transferase family 90 JAB PF01398.16 EIW79445.1 - 2.3e-15 56.3 0.0 3.6e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EIW79445.1 - 1.7e-06 27.5 0.0 4.7e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Fer4_19 PF06902.6 EIW79446.1 - 0.055 13.3 0.1 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Divergent 4Fe-4S mono-cluster Retrotrans_gag PF03732.12 EIW79448.1 - 1.1e-09 38.1 3.2 1.2e-09 38.0 1.6 1.5 1 1 0 1 1 1 1 Retrotransposon gag protein GFO_IDH_MocA PF01408.17 EIW79451.1 - 4.5e-11 43.3 0.1 7.7e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EIW79451.1 - 0.008 15.9 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain AMP-binding PF00501.23 EIW79452.1 - 4.1e-96 321.9 0.1 5.1e-96 321.6 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIW79452.1 - 4.7e-21 75.5 0.1 1.8e-20 73.6 0.1 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Crp PF00325.15 EIW79452.1 - 0.041 13.3 0.2 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 Bacterial regulatory proteins, crp family DUF1967 PF09269.6 EIW79452.1 - 0.12 12.0 0.0 0.55 9.9 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) SdpI PF13630.1 EIW79454.1 - 0.5 10.0 4.3 0.71 9.6 3.0 1.2 1 0 0 1 1 1 0 SdpI/YhfL protein family SSF PF00474.12 EIW79455.1 - 1.3e-21 76.7 31.8 1.8e-21 76.2 22.0 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family FHA PF00498.21 EIW79456.1 - 0.00061 19.8 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 FHA domain Glyco_hydro_3 PF00933.16 EIW79457.1 - 9.9e-59 198.7 0.0 1.6e-58 198.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIW79457.1 - 4.5e-46 157.1 0.9 7.7e-46 156.4 0.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIW79457.1 - 5.5e-06 26.2 0.0 1.6e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain F-box-like PF12937.2 EIW79458.1 - 1.4e-08 34.2 1.8 1.6e-08 34.0 0.1 2.1 2 0 0 2 2 2 1 F-box-like LRR_7 PF13504.1 EIW79458.1 - 2 8.9 5.4 17 6.1 0.5 4.3 4 1 0 4 4 4 0 Leucine rich repeat WD40 PF00400.27 EIW79462.1 - 1.5e-114 370.2 48.2 8.3e-12 44.5 0.2 13.2 13 0 0 13 13 13 12 WD domain, G-beta repeat eIF2A PF08662.6 EIW79462.1 - 4.9e-10 39.4 0.0 0.026 14.2 0.0 5.3 3 2 2 6 6 6 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIW79462.1 - 1.5e-07 29.9 16.4 0.16 10.0 0.0 7.3 3 2 4 7 7 7 5 Nucleoporin Nup120/160 Nbas_N PF15492.1 EIW79462.1 - 3.5e-05 23.0 2.9 3.8 6.5 0.0 6.4 2 2 5 8 8 8 1 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.1 EIW79462.1 - 0.00057 19.4 2.3 1.2 8.5 0.1 4.2 2 2 0 2 2 2 2 PQQ-like domain PD40 PF07676.7 EIW79462.1 - 0.0033 17.0 6.8 18 5.0 0.0 6.7 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 EIW79462.1 - 0.014 14.6 0.2 1.2e+02 2.1 0.0 5.7 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature Arena_nucleocap PF00843.12 EIW79462.1 - 0.069 11.0 0.1 1.8 6.3 0.0 3.0 3 1 1 4 4 4 0 Arenavirus nucleocapsid protein Nucleoporin_N PF08801.6 EIW79462.1 - 0.1 11.2 3.2 22 3.6 0.0 4.3 3 3 0 3 3 3 0 Nup133 N terminal like Peptidase_S32 PF05579.8 EIW79463.1 - 0.0013 17.7 0.2 0.0025 16.8 0.1 1.4 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Peptidase_S64 PF08192.6 EIW79463.1 - 0.01 14.2 0.0 0.015 13.6 0.0 1.1 1 0 0 1 1 1 0 Peptidase family S64 Peptidase_S3 PF00944.14 EIW79463.1 - 0.012 15.0 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 Alphavirus core protein PMM PF03332.8 EIW79463.1 - 0.046 13.2 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Eukaryotic phosphomannomutase Trypsin_2 PF13365.1 EIW79463.1 - 0.075 13.0 0.1 0.54 10.2 0.1 2.2 1 1 0 1 1 1 0 Trypsin-like peptidase domain zf-MYND PF01753.13 EIW79464.1 - 9.7e-10 38.1 5.8 9.7e-10 38.1 4.1 1.9 2 0 0 2 2 2 1 MYND finger VWA_3 PF13768.1 EIW79465.1 - 3.9e-23 81.8 0.0 8.5e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EIW79465.1 - 1.5e-12 47.9 0.0 3e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 EIW79465.1 - 1.2e-09 37.9 0.0 2.5e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 EIW79465.1 - 2.3e-08 33.9 0.0 4.2e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 EIW79465.1 - 5.1e-07 29.0 0.0 1.6e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain vWA-TerF-like PF10138.4 EIW79465.1 - 0.045 13.5 0.0 0.076 12.8 0.0 1.2 1 0 0 1 1 1 0 vWA found in TerF C terminus EMI PF07546.8 EIW79465.1 - 0.14 12.6 1.0 0.43 11.0 0.7 1.7 1 0 0 1 1 1 0 EMI domain Molybdopterin PF00384.17 EIW79466.1 - 2e-68 231.1 0.0 1.2e-67 228.5 0.0 1.9 1 1 0 1 1 1 1 Molybdopterin oxidoreductase Fer2_4 PF13510.1 EIW79466.1 - 8.2e-20 70.4 0.1 2.5e-19 68.8 0.1 1.9 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 EIW79466.1 - 5.5e-19 67.1 0.1 1.3e-18 65.9 0.1 1.7 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 EIW79466.1 - 1.7e-15 56.8 0.1 5.3e-15 55.2 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 EIW79466.1 - 7.6e-09 35.2 0.6 7.6e-09 35.2 0.4 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 EIW79466.1 - 0.0028 17.3 0.1 0.31 10.8 0.0 2.6 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.22 EIW79466.1 - 0.087 12.4 1.1 4.1 7.1 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_6 PF12837.2 EIW79466.1 - 0.27 11.1 2.4 0.46 10.4 0.6 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain VWA_3 PF13768.1 EIW79467.1 - 2.2e-24 85.9 0.0 3.9e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EIW79467.1 - 1e-16 61.5 0.0 2e-16 60.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EIW79467.1 - 1.1e-15 57.7 0.0 2e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 EIW79467.1 - 2.3e-13 49.8 0.0 3.7e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.9 EIW79467.1 - 2.9e-05 23.3 0.1 7.1e-05 22.0 0.1 1.6 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.4 EIW79467.1 - 0.00091 19.1 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VIT_2 PF13757.1 EIW79467.1 - 0.022 14.2 0.0 0.051 13.0 0.0 1.5 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain DUF2201 PF09967.4 EIW79467.1 - 0.022 14.7 0.0 0.18 11.8 0.0 2.2 2 0 0 2 2 2 0 VWA-like domain (DUF2201) AMP-binding PF00501.23 EIW79469.1 - 3.1e-32 111.4 0.3 2.1e-31 108.7 0.2 2.0 1 1 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EIW79469.1 - 3.3e-17 62.2 0.1 4.7e-08 32.2 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein PP-binding PF00550.20 EIW79469.1 - 0.00036 20.7 0.0 0.00077 19.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EIW79469.1 - 0.1 12.0 0.0 2.5 7.4 0.0 2.7 3 0 0 3 3 3 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EIW79469.1 - 0.12 12.3 3.6 0.083 12.8 0.4 2.3 2 0 0 2 2 2 0 short chain dehydrogenase Cpn60_TCP1 PF00118.19 EIW79470.1 - 1.3e-156 522.0 0.4 1.5e-156 521.8 0.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Zn_clus PF00172.13 EIW79471.1 - 1.1e-05 25.2 8.4 1.9e-05 24.4 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EIW79471.1 - 0.045 13.5 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 PAS fold PAT1 PF09770.4 EIW79471.1 - 1.3 7.1 9.1 1.8 6.7 6.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Glyco_hydro_1 PF00232.13 EIW79472.1 - 1.2e-158 528.0 1.9 1.5e-158 527.7 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_hydro_cc PF11790.3 EIW79472.1 - 0.011 15.1 0.0 0.031 13.6 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core GFO_IDH_MocA PF01408.17 EIW79473.1 - 1.7e-13 51.0 0.0 3.2e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EIW79473.1 - 1.8e-05 24.5 0.0 2.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain MatE PF01554.13 EIW79476.1 - 9.5e-44 148.8 20.8 3.9e-23 81.8 4.0 3.1 2 1 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EIW79476.1 - 2.2e-07 30.7 17.6 2.6e-07 30.5 1.2 3.3 3 0 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain MVIN PF03023.9 EIW79476.1 - 0.00022 19.7 13.7 0.00037 19.0 4.0 2.5 2 1 0 2 2 2 2 MviN-like protein zf-RVT PF13966.1 EIW79477.1 - 0.0024 18.1 0.1 0.0038 17.4 0.0 1.5 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RNase_H PF00075.19 EIW79478.1 - 1.7e-05 25.1 0.0 0.0001 22.6 0.0 2.0 2 0 0 2 2 2 1 RNase H RVT_1 PF00078.22 EIW79479.1 - 1.4e-08 34.3 0.0 1.4e-08 34.3 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC PF00098.18 EIW79482.1 - 0.027 14.3 2.2 0.027 14.3 1.5 3.1 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.1 EIW79482.1 - 0.053 13.1 0.2 0.053 13.1 0.1 3.1 3 0 0 3 3 3 0 Zinc knuckle PHD PF00628.24 EIW79482.1 - 0.14 11.8 13.3 0.26 11.0 0.1 2.8 2 1 0 2 2 2 0 PHD-finger zf-ribbon_3 PF13248.1 EIW79482.1 - 7.6 5.8 12.2 3 7.1 0.2 3.0 2 1 0 2 2 2 0 zinc-ribbon domain Retinal PF15449.1 EIW79484.1 - 0.055 11.1 1.2 0.06 11.0 0.8 1.1 1 0 0 1 1 1 0 Retinal protein DUF3267 PF11667.3 EIW79486.1 - 0.12 12.5 0.2 0.12 12.5 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3267) COX4_pro PF03626.9 EIW79486.1 - 0.22 11.6 3.0 0.15 12.1 0.6 1.8 1 1 1 2 2 2 0 Prokaryotic Cytochrome C oxidase subunit IV Tir_receptor_N PF07490.6 EIW79490.1 - 0.15 11.6 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus WD40 PF00400.27 EIW79492.1 - 4e-26 89.9 10.4 3e-06 26.8 1.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.7 EIW79492.1 - 8.6e-16 57.7 0.0 1.8e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain zf-MYND PF01753.13 EIW79494.1 - 0.012 15.5 0.4 0.024 14.5 0.3 1.5 1 0 0 1 1 1 0 MYND finger DEAD PF00270.24 EIW79496.1 - 3.2e-11 42.9 0.0 7e-11 41.9 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW79496.1 - 4.8e-11 42.3 0.0 6.4e-09 35.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW79496.1 - 0.0077 16.0 0.0 0.019 14.7 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.9 EIW79496.1 - 0.03 13.5 0.0 0.051 12.8 0.0 1.3 1 0 0 1 1 1 0 SecA DEAD-like domain DUF3518 PF12031.3 EIW79496.1 - 0.1 11.3 0.1 0.17 10.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3518) HTH_AraC PF00165.18 EIW79499.1 - 0.023 14.5 0.0 0.12 12.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 EIW79499.1 - 0.094 12.8 0.5 2.3 8.3 0.0 2.7 3 0 0 3 3 3 0 Helix-turn-helix domain HTH_3 PF01381.17 EIW79499.1 - 0.13 12.0 0.1 18 5.2 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix DUF2461 PF09365.5 EIW79501.1 - 6.2e-62 208.7 0.0 7.7e-62 208.4 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) DUF4451 PF14616.1 EIW79502.1 - 4.5e-09 36.1 8.9 0.011 15.4 0.2 3.1 3 0 0 3 3 3 3 Domain of unknown function (DUF4451) HypA PF01155.14 EIW79502.1 - 0.021 14.4 5.0 1.4 8.6 0.2 3.1 2 1 0 3 3 3 0 Hydrogenase expression/synthesis hypA family zf-dskA_traR PF01258.12 EIW79502.1 - 0.14 11.8 2.8 12 5.7 0.1 3.3 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger IBR PF01485.16 EIW79502.1 - 2.2 8.2 6.8 38 4.2 2.2 3.3 2 1 1 3 3 3 0 IBR domain FAA_hydrolase_N PF09298.6 EIW79502.1 - 4.5 7.3 5.5 3.5 7.6 2.0 2.0 1 1 1 2 2 2 0 Fumarylacetoacetase N-terminal DUF4451 PF14616.1 EIW79503.1 - 0.0018 18.0 0.4 0.0029 17.3 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) SecY PF00344.15 EIW79504.1 - 4.2e-97 325.1 8.4 5.4e-97 324.8 5.8 1.1 1 0 0 1 1 1 1 SecY translocase SURF6 PF04935.7 EIW79504.1 - 1.2e-34 119.4 35.6 1.2e-34 119.4 24.7 1.9 2 0 0 2 2 2 1 Surfeit locus protein 6 Plug_translocon PF10559.4 EIW79504.1 - 4.4e-19 67.6 0.2 1.2e-18 66.3 0.1 1.8 1 0 0 1 1 1 1 Plug domain of Sec61p RRP14 PF15459.1 EIW79504.1 - 0.00083 19.3 3.3 0.00083 19.3 2.3 3.8 3 0 0 3 3 3 1 60S ribosome biogenesis protein Rrp14 Lipase_GDSL PF00657.17 EIW79505.1 - 7e-09 35.8 1.4 1.4e-08 34.8 1.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EIW79505.1 - 0.00013 22.1 0.4 0.00019 21.6 0.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MutS_V PF00488.16 EIW79505.1 - 0.068 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 MutS domain V Peptidase_A4 PF01828.12 EIW79506.1 - 3.3e-77 258.2 10.8 3.8e-77 258.0 7.5 1.0 1 0 0 1 1 1 1 Peptidase A4 family Fungal_trans PF04082.13 EIW79508.1 - 3.5e-09 35.9 0.0 5.1e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW79508.1 - 0.0037 17.1 2.3 0.0061 16.4 1.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CCHC_3 PF13917.1 EIW79508.1 - 0.046 13.4 0.8 0.26 11.0 0.2 2.2 2 0 0 2 2 2 0 Zinc knuckle Copper-fist PF00649.13 EIW79508.1 - 0.2 10.8 1.1 0.39 9.9 0.8 1.4 1 0 0 1 1 1 0 Copper fist DNA binding domain MFS_1 PF07690.11 EIW79509.1 - 6.3e-19 67.8 30.6 6.3e-19 67.8 21.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EIW79509.1 - 1.3e-13 50.6 7.7 4.4e-13 49.0 5.4 1.9 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 zf-C2H2_4 PF13894.1 EIW79510.1 - 0.97 9.9 9.1 1.2 9.6 0.7 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger DZR PF12773.2 EIW79510.1 - 3.1 7.6 7.4 5.2 6.9 0.7 2.6 2 1 0 2 2 2 0 Double zinc ribbon RTA1 PF04479.8 EIW79512.1 - 9.8e-32 110.2 4.6 9.8e-32 110.2 3.2 1.5 2 0 0 2 2 2 1 RTA1 like protein DUF373 PF04123.8 EIW79512.1 - 0.2 10.6 4.2 0.12 11.3 1.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DUF4131 PF13567.1 EIW79512.1 - 1.1 8.7 13.2 0.29 10.5 2.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF485 PF04341.7 EIW79512.1 - 4.5 7.0 8.3 4.4 7.0 1.6 2.5 2 0 0 2 2 2 0 Protein of unknown function, DUF485 F-box-like PF12937.2 EIW79518.1 - 0.02 14.6 0.0 0.056 13.1 0.0 1.8 1 0 0 1 1 1 0 F-box-like N2227 PF07942.7 EIW79519.1 - 1.5e-93 312.6 0.0 2.2e-93 312.1 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EIW79519.1 - 0.001 18.8 0.0 0.0024 17.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW79519.1 - 0.091 13.2 0.0 0.49 10.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EIW79519.1 - 0.1 13.0 0.0 0.42 11.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Virul_fac_BrkB PF03631.10 EIW79519.1 - 0.18 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Virulence factor BrkB DUF668 PF05003.7 EIW79519.1 - 0.19 11.9 0.3 0.74 10.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF668) Zip PF02535.17 EIW79519.1 - 3.5 6.5 7.5 5.4 5.9 5.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 EIW79519.1 - 5.2 6.3 17.4 9.7 5.4 12.1 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region F-box-like PF12937.2 EIW79521.1 - 0.018 14.7 0.0 0.059 13.0 0.0 1.9 1 0 0 1 1 1 0 F-box-like GTP_EFTU_D2 PF03144.20 EIW79521.1 - 0.18 11.9 0.0 0.4 10.8 0.0 1.4 1 0 0 1 1 1 0 Elongation factor Tu domain 2 DUF4185 PF13810.1 EIW79522.1 - 0.00027 19.9 0.1 0.00047 19.1 0.1 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4185) ATE_C PF04377.10 EIW79522.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, C terminus Abhydrolase_6 PF12697.2 EIW79525.1 - 2.2e-21 76.8 0.5 2.8e-21 76.4 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW79525.1 - 1.6e-12 47.3 0.0 2.9e-12 46.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EIW79525.1 - 8.9e-07 28.6 0.2 0.011 15.3 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase Abhydrolase_1 PF00561.15 EIW79525.1 - 9.5e-07 28.5 0.1 0.0034 16.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EIW79525.1 - 0.0068 16.2 0.1 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 EIW79525.1 - 0.0081 15.9 0.0 0.27 11.1 0.0 2.5 2 0 0 2 2 2 1 Putative lysophospholipase Methyltransf_25 PF13649.1 EIW79526.1 - 0.00012 22.3 0.2 0.00082 19.6 0.1 2.3 2 1 0 2 2 2 1 Methyltransferase domain FAD-oxidase_C PF02913.14 EIW79527.1 - 1.3e-51 175.2 0.1 1.5e-50 171.8 0.0 2.0 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EIW79527.1 - 5.5e-29 100.4 0.5 8.7e-29 99.7 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Succ_CoA_lig PF13607.1 EIW79527.1 - 0.095 12.2 0.4 0.2 11.2 0.0 1.7 2 0 0 2 2 2 0 Succinyl-CoA ligase like flavodoxin domain Sugar_tr PF00083.19 EIW79528.1 - 1.8e-108 363.0 20.8 2.1e-108 362.7 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW79528.1 - 1e-20 73.8 25.3 1e-20 73.8 17.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3521 PF12035.3 EIW79528.1 - 0.11 12.2 0.1 0.57 10.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3521) DUF1930 PF09122.5 EIW79528.1 - 0.16 11.7 0.1 0.35 10.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1930) Hydrophobin PF01185.13 EIW79529.1 - 3e-19 69.2 8.2 3.7e-19 68.9 5.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 EIW79530.1 - 1.6e-20 73.3 12.3 1.9e-20 73.0 8.5 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Peroxin-3 PF04882.7 EIW79531.1 - 3.3e-73 246.8 0.0 1.2e-62 212.0 0.0 2.7 2 1 0 2 2 2 2 Peroxin-3 DUF3735 PF12537.3 EIW79534.1 - 0.073 13.1 0.2 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3735) E1-E2_ATPase PF00122.15 EIW79535.1 - 8.2 5.3 10.6 0.88 8.5 0.6 2.2 1 1 1 2 2 2 0 E1-E2 ATPase MFS_1 PF07690.11 EIW79536.1 - 9.9e-38 129.7 41.9 9.9e-38 129.7 29.0 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIW79536.1 - 2.2e-12 45.9 25.0 1.8e-10 39.6 17.3 2.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIW79536.1 - 1.6e-06 27.0 10.9 1.6e-06 27.0 7.5 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter adh_short PF00106.20 EIW79537.1 - 0.057 13.3 0.0 10 6.0 0.0 2.6 2 1 0 2 2 2 0 short chain dehydrogenase p450 PF00067.17 EIW79538.1 - 1.5e-29 102.8 0.1 9.2e-29 100.2 0.1 1.9 1 1 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.8 EIW79539.1 - 3.1e-24 85.7 0.1 4.3e-24 85.2 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIW79539.1 - 9.3e-17 60.7 0.0 1.3e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EIW79539.1 - 0.00017 21.3 0.1 0.0003 20.5 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family tRNA_U5-meth_tr PF05958.6 EIW79539.1 - 0.072 11.7 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase p450 PF00067.17 EIW79541.1 - 4.3e-53 180.4 0.0 5.9e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_N PF00732.14 EIW79544.1 - 3.3e-69 233.3 0.0 4.6e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIW79544.1 - 5.4e-34 117.5 0.2 8.7e-34 116.8 0.2 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIW79544.1 - 1.8e-05 23.8 2.4 0.00023 20.1 1.6 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIW79544.1 - 0.00058 18.8 0.1 0.00091 18.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EIW79544.1 - 0.00078 19.4 0.1 0.0022 17.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIW79544.1 - 0.0011 17.9 1.6 0.0072 15.2 1.1 2.2 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIW79544.1 - 0.0047 16.8 0.0 0.0083 16.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF3759 PF12585.3 EIW79545.1 - 2e-34 117.3 6.4 2.3e-34 117.1 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Peptidase_A8 PF01252.13 EIW79545.1 - 0.14 11.7 0.0 0.15 11.6 0.0 1.1 1 0 0 1 1 1 0 Signal peptidase (SPase) II DUF3759 PF12585.3 EIW79547.1 - 8.6e-33 112.1 3.4 1.1e-32 111.7 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Phe_ZIP PF08916.6 EIW79547.1 - 0.16 12.2 1.0 0.25 11.6 0.7 1.3 1 0 0 1 1 1 0 Phenylalanine zipper DUF1308 PF07000.6 EIW79548.1 - 7.4e-30 103.8 0.0 2.9e-29 101.8 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1308) COesterase PF00135.23 EIW79549.1 - 2.3e-74 251.0 0.4 2.6e-74 250.8 0.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW79549.1 - 8e-07 28.8 0.1 8.4e-06 25.5 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW79549.1 - 0.0028 17.4 0.2 0.067 12.9 0.0 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIW79550.1 - 7.6e-37 126.6 0.1 1.2e-36 125.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIW79550.1 - 5.3e-09 35.9 0.0 2.2e-08 34.0 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EIW79550.1 - 3.6e-07 29.8 0.0 0.012 15.0 0.0 2.4 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EIW79550.1 - 4.9e-06 26.5 0.0 1.2e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EIW79550.1 - 1e-05 24.9 0.0 3.7e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EIW79550.1 - 2.4e-05 23.8 0.0 0.014 14.7 0.0 2.4 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EIW79550.1 - 0.0051 16.4 0.1 0.02 14.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 EIW79550.1 - 0.0059 15.1 0.4 0.78 8.1 0.3 2.7 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) PAF-AH_p_II PF03403.8 EIW79550.1 - 0.0077 14.5 0.0 0.015 13.6 0.0 1.4 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II DPPIV_N PF00930.16 EIW79550.1 - 0.087 11.3 0.0 3.7 6.0 0.0 2.6 2 1 1 3 3 3 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region MFS_1 PF07690.11 EIW79551.1 - 1.8e-21 76.2 21.3 2.3e-21 75.9 14.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_2 PF00891.13 EIW79552.1 - 1.8e-21 76.4 0.6 5.9e-18 64.9 0.1 3.6 3 1 0 3 3 3 2 O-methyltransferase Methyltransf_23 PF13489.1 EIW79552.1 - 0.018 14.7 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EIW79552.1 - 0.21 11.0 0.0 0.36 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SET PF00856.23 EIW79553.1 - 1.2e-11 45.1 0.0 1.1e-08 35.6 0.0 2.2 2 0 0 2 2 2 2 SET domain NACHT PF05729.7 EIW79555.1 - 6.2e-10 38.9 0.0 1.7e-09 37.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW79555.1 - 2e-07 31.2 0.1 9.5e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 EIW79555.1 - 0.0012 18.0 0.0 0.0026 16.8 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Arch_ATPase PF01637.13 EIW79555.1 - 0.0016 18.2 0.0 0.0026 17.4 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_19 PF13245.1 EIW79555.1 - 0.002 17.8 0.0 0.0062 16.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EIW79555.1 - 0.004 17.9 0.0 0.013 16.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIW79555.1 - 0.0055 17.0 0.1 0.017 15.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_22 PF13401.1 EIW79555.1 - 0.0088 16.1 0.0 0.022 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EIW79555.1 - 0.021 13.8 0.0 0.035 13.1 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EIW79555.1 - 0.025 14.7 0.0 0.094 12.8 0.0 2.0 2 0 0 2 2 1 0 RNA helicase AAA PF00004.24 EIW79555.1 - 0.029 14.5 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) WD40 PF00400.27 EIW79555.1 - 0.04 13.8 1.1 13 5.9 0.0 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat APS_kinase PF01583.15 EIW79555.1 - 0.065 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_29 PF13555.1 EIW79555.1 - 0.11 12.0 0.0 0.86 9.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF815 PF05673.8 EIW79555.1 - 0.13 11.1 0.0 0.24 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SspH PF08141.7 EIW79555.1 - 0.14 12.2 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Small acid-soluble spore protein H family Sigma54_activ_2 PF14532.1 EIW79555.1 - 0.15 12.1 0.0 0.47 10.5 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain TrwB_AAD_bind PF10412.4 EIW79555.1 - 0.15 10.6 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_33 PF13671.1 EIW79555.1 - 0.16 11.8 0.0 0.47 10.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain M20_dimer PF07687.9 EIW79557.1 - 8.8e-09 35.0 0.1 2.2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EIW79557.1 - 2.2e-08 33.8 0.4 3.6e-08 33.1 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DUF4410 PF14366.1 EIW79557.1 - 0.026 14.2 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) WD40 PF00400.27 EIW79559.1 - 4.5e-41 137.2 7.0 2.3e-12 46.2 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 EIW79559.1 - 0.0017 16.6 0.1 0.57 8.2 0.2 3.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 DUF2051 PF09738.4 EIW79559.1 - 0.16 11.2 0.4 9.2 5.4 0.0 2.1 2 0 0 2 2 2 0 Double stranded RNA binding protein (DUF2051) Aldedh PF00171.17 EIW79561.1 - 3.9e-121 404.5 0.0 4.7e-121 404.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HCV_NS5a_1a PF08300.8 EIW79561.1 - 0.031 14.1 0.0 0.078 12.9 0.0 1.6 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a zinc finger domain WD40 PF00400.27 EIW79562.1 - 1e-11 44.2 5.1 0.0034 17.2 0.0 4.7 4 1 1 5 5 5 3 WD domain, G-beta repeat Ribonuc_2-5A PF06479.7 EIW79563.1 - 1.6e-45 154.0 0.1 2.6e-45 153.4 0.1 1.3 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 EIW79563.1 - 1.5e-36 125.8 0.0 2.2e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW79563.1 - 8.3e-18 64.3 0.0 3.8e-16 58.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EIW79563.1 - 0.13 11.3 0.0 0.27 10.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family tRNA-synt_2b PF00587.20 EIW79564.1 - 1e-32 113.0 0.0 1.8e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EIW79564.1 - 7.6e-20 70.9 8.0 7.6e-20 70.9 5.5 1.9 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.7 EIW79564.1 - 0.0042 16.8 5.5 0.0082 15.8 3.8 1.5 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein DUF3450 PF11932.3 EIW79564.1 - 0.01 15.1 2.5 0.019 14.2 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) tRNA-synt_His PF13393.1 EIW79564.1 - 0.075 12.0 0.9 0.51 9.3 0.0 2.0 2 0 0 2 2 2 0 Histidyl-tRNA synthetase DUF2228 PF10228.4 EIW79564.1 - 0.12 11.9 2.7 0.19 11.2 1.9 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) DUF1178 PF06676.6 EIW79564.1 - 0.91 9.7 10.3 5.6 7.1 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) NACHT PF05729.7 EIW79568.1 - 2.2e-09 37.2 0.1 2.7e-08 33.6 0.0 2.3 2 0 0 2 2 2 1 NACHT domain Arch_ATPase PF01637.13 EIW79568.1 - 0.0011 18.6 0.0 0.0018 18.0 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase APS_kinase PF01583.15 EIW79568.1 - 0.0022 17.6 0.0 0.0039 16.8 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.1 EIW79568.1 - 0.0063 16.5 0.1 0.019 14.9 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EIW79568.1 - 0.015 15.4 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EIW79568.1 - 0.021 15.6 0.0 0.054 14.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIW79568.1 - 0.022 15.0 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EIW79568.1 - 0.026 14.4 0.0 0.85 9.4 0.0 2.7 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EIW79568.1 - 0.026 14.6 0.0 0.056 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.7 EIW79568.1 - 0.045 12.8 0.0 0.16 11.0 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_29 PF13555.1 EIW79568.1 - 0.099 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 EIW79568.1 - 0.16 10.8 0.0 0.27 10.1 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Synaptobrevin PF00957.16 EIW79570.1 - 0.41 10.2 1.0 0.66 9.6 0.7 1.3 1 0 0 1 1 1 0 Synaptobrevin NT-C2 PF10358.4 EIW79571.1 - 3.1e-15 55.9 0.0 1.5e-11 43.9 0.0 3.0 2 1 0 2 2 2 2 N-terminal C2 in EEIG1 and EHBP1 proteins Metallophos PF00149.23 EIW79572.1 - 3.5e-07 29.8 8.0 7.7e-06 25.4 5.0 3.1 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIW79572.1 - 0.028 14.2 0.0 0.13 12.0 0.0 2.1 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain UL11 PF11094.3 EIW79572.1 - 0.063 13.1 0.1 0.15 11.9 0.1 1.6 1 0 0 1 1 1 0 Membrane-associated tegument protein F-box PF00646.28 EIW79573.1 - 5.2e-06 25.9 0.0 1.2e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW79573.1 - 0.00011 21.8 0.2 0.0003 20.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like Ribosomal_L28 PF00830.14 EIW79575.1 - 7.8e-19 67.2 0.4 1.7e-18 66.2 0.3 1.6 1 0 0 1 1 1 1 Ribosomal L28 family Cwf_Cwc_15 PF04889.7 EIW79575.1 - 0.66 9.6 17.1 1 9.0 11.9 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein FAD-oxidase_C PF02913.14 EIW79575.1 - 1.1 8.5 5.2 1 8.5 3.1 1.3 1 1 0 1 1 1 0 FAD linked oxidases, C-terminal domain GWT1 PF06423.7 EIW79576.1 - 1.9e-38 131.6 0.6 5.1e-38 130.2 0.0 2.1 2 0 0 2 2 2 1 GWT1 PAS_9 PF13426.1 EIW79576.1 - 0.081 13.3 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 PAS domain DUF4063 PF13272.1 EIW79576.1 - 0.25 11.1 0.1 0.25 11.1 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4063) DUF607 PF04678.8 EIW79577.1 - 2.6e-43 148.0 0.0 4.6e-43 147.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF607 AA_permease_2 PF13520.1 EIW79578.1 - 2.9e-38 131.5 53.4 1.3e-37 129.3 37.0 1.8 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIW79578.1 - 2.6e-13 49.1 40.5 2.6e-13 49.1 28.1 1.3 2 0 0 2 2 2 1 Amino acid permease Endomucin PF07010.7 EIW79579.1 - 0.018 14.4 1.0 0.026 13.8 0.1 1.7 2 0 0 2 2 2 0 Endomucin zf-MYND PF01753.13 EIW79581.1 - 5.3e-07 29.4 12.7 9.5e-07 28.5 8.8 1.4 1 0 0 1 1 1 1 MYND finger GtrA PF04138.9 EIW79582.1 - 0.098 12.6 2.5 0.21 11.5 1.7 1.6 1 1 0 1 1 1 0 GtrA-like protein DIOX_N PF14226.1 EIW79583.1 - 1.2e-15 58.0 0.0 3.6e-15 56.5 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIW79583.1 - 3.5e-12 46.4 0.1 1.2e-11 44.7 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EIW79584.1 - 3.8e-15 56.4 0.0 8.3e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIW79584.1 - 1.8e-10 40.9 0.0 6.2e-10 39.2 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EIW79585.1 - 6.9e-16 58.8 0.2 1.7e-15 57.5 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIW79585.1 - 6.4e-12 45.6 0.1 1.6e-11 44.3 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EIW79586.1 - 3.7e-16 59.6 0.0 7.7e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIW79586.1 - 2.6e-12 46.8 0.0 6e-12 45.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EIW79587.1 - 5.2e-17 62.4 0.0 1e-16 61.4 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIW79587.1 - 3.5e-13 49.6 0.0 7.9e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EIW79588.1 - 1.6e-17 64.1 0.0 3.4e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIW79588.1 - 8.6e-13 48.4 0.0 1.6e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EIW79589.1 - 2e-16 60.5 0.1 4.6e-16 59.4 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIW79589.1 - 1.3e-13 51.0 0.0 2.2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2275 PF10039.4 EIW79590.1 - 0.021 14.7 0.1 0.04 13.8 0.1 1.3 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) Tetraspannin PF00335.15 EIW79590.1 - 0.096 11.9 0.5 0.15 11.3 0.3 1.2 1 0 0 1 1 1 0 Tetraspanin family Peptidase_S10 PF00450.17 EIW79591.1 - 1.4e-94 317.6 1.2 1.7e-94 317.3 0.8 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Exo70 PF03081.10 EIW79591.1 - 0.21 10.3 0.0 0.32 9.7 0.0 1.2 1 0 0 1 1 1 0 Exo70 exocyst complex subunit Peptidase_S10 PF00450.17 EIW79592.1 - 1.8e-91 307.3 4.2 2.2e-91 307.1 2.9 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_5 PF12695.2 EIW79592.1 - 0.015 15.0 0.0 0.05 13.3 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family GPI-anchored PF10342.4 EIW79593.1 - 5.6e-07 29.9 0.3 5.6e-07 29.9 0.2 1.6 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family FHA PF00498.21 EIW79594.1 - 0.0038 17.3 0.0 0.012 15.6 0.0 1.8 1 1 0 1 1 1 1 FHA domain MaoC_dehydratas PF01575.14 EIW79595.1 - 2.1e-27 94.9 0.0 5.7e-27 93.5 0.0 1.7 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EIW79595.1 - 9.1e-07 28.7 0.0 0.00044 20.0 0.0 2.8 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase Cellulase PF00150.13 EIW79596.1 - 2.7e-08 33.3 0.0 2e-05 23.9 0.0 2.7 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) F-box-like PF12937.2 EIW79598.1 - 6.3e-08 32.2 5.7 6.3e-08 32.2 3.9 2.0 2 0 0 2 2 2 1 F-box-like Spt5-NGN PF03439.8 EIW79602.1 - 1e-21 76.4 0.0 1.9e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section CTD PF12815.2 EIW79602.1 - 5.9e-14 52.5 67.1 3.5e-09 37.1 13.4 4.0 1 1 2 3 3 3 3 Spt5 C-terminal nonapeptide repeat binding Spt4 KOW PF00467.24 EIW79602.1 - 4.9e-13 48.2 17.9 1.7e-06 27.4 0.1 6.6 7 0 0 7 7 7 3 KOW motif Spt5_N PF11942.3 EIW79602.1 - 6.5e-12 45.9 9.9 6.5e-12 45.9 6.9 3.4 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal YajC PF02699.10 EIW79602.1 - 0.39 10.4 3.4 0.65 9.7 0.4 2.6 2 1 1 3 3 3 0 Preprotein translocase subunit Peptidase_M19 PF01244.16 EIW79603.1 - 2.6e-102 342.0 0.0 3e-102 341.8 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) F-box-like PF12937.2 EIW79604.1 - 4e-09 36.0 3.6 4e-09 36.0 2.5 2.2 2 0 0 2 2 2 1 F-box-like LRR_2 PF07723.8 EIW79604.1 - 0.5 10.9 4.9 4.3 7.9 0.3 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat APH PF01636.18 EIW79606.1 - 8.2e-18 64.9 0.1 1.3e-15 57.7 0.0 3.2 3 1 0 3 3 3 1 Phosphotransferase enzyme family DUF677 PF05055.7 EIW79607.1 - 0.15 10.6 0.1 0.21 10.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF3245 PF11595.3 EIW79607.1 - 3.5 7.8 6.3 2.3 8.4 2.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Transposase_21 PF02992.9 EIW79610.1 - 0.00024 20.2 1.1 0.00054 19.1 0.1 1.8 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIW79610.1 - 0.0016 17.8 0.1 0.0047 16.3 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Abhydrolase_6 PF12697.2 EIW79611.1 - 3.5e-26 92.5 0.0 4.1e-26 92.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW79611.1 - 3.9e-16 59.3 0.0 1e-15 57.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW79611.1 - 2.8e-10 40.1 0.0 1.3e-09 37.9 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EIW79611.1 - 0.0002 20.8 0.0 0.00035 20.0 0.0 1.4 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 EIW79611.1 - 0.016 15.0 0.0 0.04 13.7 0.0 1.7 2 0 0 2 2 2 0 Putative lysophospholipase PGAP1 PF07819.8 EIW79611.1 - 0.018 14.6 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.15 EIW79611.1 - 0.046 13.9 0.1 0.087 13.0 0.1 1.6 1 1 0 1 1 1 0 Thioesterase domain Nsp3_PL2pro PF12124.3 EIW79611.1 - 0.12 12.0 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Coronavirus polyprotein cleavage domain Peptidase_S9 PF00326.16 EIW79611.1 - 0.13 11.4 0.0 4.9 6.3 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ndr PF03096.9 EIW79611.1 - 0.15 10.4 0.0 0.7 8.3 0.0 1.8 2 0 0 2 2 2 0 Ndr family Glyco_hydro_31 PF01055.21 EIW79612.1 - 3.7e-67 227.0 7.9 1.8e-66 224.7 5.5 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EIW79612.1 - 8.6e-08 31.9 0.0 2.2e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like zf-C3HC4_2 PF13923.1 EIW79613.1 - 5.1e-09 36.0 21.1 1.7e-05 24.7 1.3 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW79613.1 - 1e-08 34.6 19.0 1.9e-05 24.2 6.5 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EIW79613.1 - 3e-07 29.9 16.3 3e-05 23.3 0.8 2.7 2 1 1 3 3 3 2 Rtf2 RING-finger zf-RING_2 PF13639.1 EIW79613.1 - 1.4e-06 27.9 18.4 0.0025 17.6 0.9 2.3 2 0 0 2 2 2 2 Ring finger domain zf-RING_5 PF14634.1 EIW79613.1 - 7.4e-06 25.5 22.2 3.6e-05 23.3 7.3 2.8 2 1 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.20 EIW79613.1 - 0.00012 21.6 22.4 0.022 14.4 1.7 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) Atg14 PF10186.4 EIW79613.1 - 0.0024 16.8 3.8 0.0024 16.8 2.7 1.6 2 0 0 2 2 2 1 UV radiation resistance protein and autophagy-related subunit 14 Vps39_2 PF10367.4 EIW79613.1 - 0.011 15.8 1.4 0.011 15.8 1.0 3.0 4 0 0 4 4 4 0 Vacuolar sorting protein 39 domain 2 zf-RING_6 PF14835.1 EIW79613.1 - 0.022 14.5 6.7 0.2 11.4 0.1 2.5 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EIW79613.1 - 0.033 14.0 1.5 0.033 14.0 1.0 3.2 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EIW79613.1 - 0.53 10.0 15.2 3.5 7.4 0.4 2.6 2 0 0 2 2 2 0 RING-type zinc-finger LIM PF00412.17 EIW79613.1 - 2.5 8.2 14.8 0.09 12.8 1.6 3.1 3 0 0 3 3 3 0 LIM domain FYVE PF01363.16 EIW79613.1 - 2.7 7.9 14.2 5.4 6.9 4.3 2.8 2 1 0 2 2 2 0 FYVE zinc finger DUF4407 PF14362.1 EIW79613.1 - 3.5 6.4 6.7 4.9 6.0 4.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-CHY PF05495.7 EIW79613.1 - 5.7 7.1 14.2 1.1 9.4 4.0 2.4 2 0 0 2 2 2 0 CHY zinc finger zf-P11 PF03854.9 EIW79613.1 - 8 6.0 15.9 6 6.4 1.0 2.4 2 0 0 2 2 2 0 P-11 zinc finger CCDC84 PF14968.1 EIW79614.1 - 0.0096 15.4 1.9 0.012 15.1 1.3 1.1 1 0 0 1 1 1 1 Coiled coil protein 84 Ctr PF04145.10 EIW79614.1 - 0.058 13.4 0.0 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 Ctr copper transporter family Shisa PF13908.1 EIW79614.1 - 0.062 13.4 11.8 0.94 9.6 8.2 2.2 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator GP41 PF00517.12 EIW79614.1 - 0.068 12.7 0.0 0.095 12.2 0.0 1.1 1 0 0 1 1 1 0 Retroviral envelope protein RCR PF12273.3 EIW79614.1 - 0.49 10.9 6.3 0.92 10.0 4.3 1.6 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red LEAP-2 PF07359.6 EIW79614.1 - 8.1 6.1 6.6 6.2 6.5 1.1 2.8 2 1 1 3 3 3 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) adh_short PF00106.20 EIW79615.1 - 5.9e-20 71.8 0.0 7.5e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW79615.1 - 8.2e-08 32.1 0.0 1.3e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIW79615.1 - 7.5e-06 25.8 0.0 9.1e-06 25.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EIW79615.1 - 0.00042 19.8 0.0 0.00064 19.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EIW79615.1 - 0.0026 16.8 0.1 0.0036 16.3 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DUF1858 PF08984.6 EIW79615.1 - 0.014 15.0 0.0 0.027 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1858) NAD_binding_10 PF13460.1 EIW79615.1 - 0.027 14.4 0.0 0.038 14.0 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding DUF1776 PF08643.5 EIW79615.1 - 0.037 13.1 0.0 0.05 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Amidase PF01425.16 EIW79617.1 - 2.4e-79 267.2 0.0 3.2e-78 263.5 0.0 1.9 1 1 0 1 1 1 1 Amidase Pro_isomerase PF00160.16 EIW79618.1 - 4.4e-41 140.6 0.2 6.1e-41 140.2 0.2 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EIW79618.1 - 1.9e-09 37.0 2.5 0.00039 19.9 0.0 2.6 1 1 2 3 3 3 3 TPR repeat TPR_2 PF07719.12 EIW79618.1 - 3.5e-06 26.4 1.7 0.008 16.0 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIW79618.1 - 5.1e-05 22.6 0.6 0.0043 16.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIW79618.1 - 2.8 7.9 8.2 1.6 8.7 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Exo_endo_phos PF03372.18 EIW79619.1 - 6.4e-13 49.2 0.0 4.9e-12 46.3 0.0 2.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 EIW79619.1 - 9.1e-05 22.1 0.0 0.00021 20.9 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain PapD-like PF14874.1 EIW79619.1 - 0.17 11.8 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Flagellar-associated PapD-like HABP4_PAI-RBP1 PF04774.10 EIW79620.1 - 1.6e-05 25.3 4.5 2.5e-05 24.7 3.1 1.2 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family Glyco_transf_22 PF03901.12 EIW79621.1 - 6.1e-66 223.1 15.9 7.3e-66 222.8 11.0 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.1 EIW79621.1 - 0.00059 19.7 7.0 0.00059 19.7 4.8 2.8 3 0 0 3 3 3 1 Dolichyl-phosphate-mannose-protein mannosyltransferase TFIIS_C PF01096.13 EIW79622.1 - 4.1e-12 45.5 1.7 4.1e-12 45.5 1.2 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EIW79622.1 - 1e-10 41.0 1.7 1e-10 41.0 1.2 3.6 4 0 0 4 4 4 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1 PF03811.8 EIW79622.1 - 0.0008 18.8 0.7 0.0008 18.8 0.5 2.6 3 0 0 3 3 3 1 InsA N-terminal domain Lar_restr_allev PF14354.1 EIW79622.1 - 0.0033 17.7 0.5 0.0033 17.7 0.3 2.1 2 1 0 2 2 2 1 Restriction alleviation protein Lar zf-CHY PF05495.7 EIW79622.1 - 0.0056 16.8 8.1 0.012 15.7 0.2 2.4 2 1 1 3 3 3 1 CHY zinc finger Elf1 PF05129.8 EIW79622.1 - 0.042 13.5 4.1 0.12 12.0 0.1 2.3 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-C2H2 PF00096.21 EIW79622.1 - 0.087 13.2 0.4 0.087 13.2 0.3 3.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type C1_1 PF00130.17 EIW79622.1 - 0.11 12.2 4.2 0.3 10.8 0.2 2.6 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_4 PF07975.7 EIW79622.1 - 0.11 12.4 10.8 0.56 10.2 0.6 3.1 1 1 2 3 3 3 0 TFIIH C1-like domain Cytochrom_c3_2 PF14537.1 EIW79622.1 - 0.17 12.2 0.2 0.17 12.2 0.1 2.0 2 1 0 2 2 2 0 Cytochrome c3 Multi-haem_cyto PF13447.1 EIW79622.1 - 0.24 10.4 3.7 1.5 7.8 0.2 2.2 1 1 1 2 2 2 0 Seven times multi-haem cytochrome CxxCH Zn_Tnp_IS1595 PF12760.2 EIW79622.1 - 0.54 10.0 10.9 7.2 6.5 2.5 3.1 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Zn-ribbon_8 PF09723.5 EIW79622.1 - 1.2 9.1 7.1 19 5.3 0.0 3.7 4 0 0 4 4 4 0 Zinc ribbon domain GFA PF04828.9 EIW79622.1 - 1.8 8.5 6.8 1.8 8.5 0.3 2.6 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme C1_3 PF07649.7 EIW79622.1 - 1.9 8.6 8.2 17 5.5 0.9 3.5 3 1 0 3 3 3 0 C1-like domain Cytochrome_C7 PF14522.1 EIW79622.1 - 2.8 7.6 5.5 0.47 10.1 0.3 2.1 1 1 1 2 2 1 0 Cytochrome c7 Prim_Zn_Ribbon PF08273.7 EIW79622.1 - 5.6 7.1 9.7 1.4 9.0 1.7 2.9 3 1 0 3 3 3 0 Zinc-binding domain of primase-helicase FYVE PF01363.16 EIW79622.1 - 6.4 6.7 10.1 7.1 6.6 0.8 2.5 2 1 0 2 2 2 0 FYVE zinc finger HNH_5 PF14279.1 EIW79622.1 - 6.5 6.8 6.1 16 5.5 0.0 3.0 3 1 1 4 4 4 0 HNH endonuclease LIM PF00412.17 EIW79622.1 - 6.7 6.8 7.6 14 5.8 0.1 2.8 3 0 0 3 3 3 0 LIM domain zf-ribbon_3 PF13248.1 EIW79622.1 - 7 6.0 7.8 29 4.0 0.1 3.3 4 0 0 4 4 4 0 zinc-ribbon domain Hydrophobin PF01185.13 EIW79624.1 - 1.5e-21 76.6 9.8 2e-21 76.1 6.8 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_12 PF07740.7 EIW79624.1 - 6.1 7.4 12.1 4.9 7.7 1.9 2.6 3 0 0 3 3 3 0 Ion channel inhibitory toxin Ribosomal_L27e PF01777.13 EIW79625.1 - 9.4e-36 121.8 2.1 1.3e-35 121.3 1.5 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.24 EIW79625.1 - 0.0019 17.8 0.6 0.004 16.8 0.4 1.6 1 0 0 1 1 1 1 KOW motif Nup54 PF13874.1 EIW79626.1 - 3.5e-30 104.5 5.6 3.5e-30 104.5 3.9 1.9 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 EIW79626.1 - 9.6e-29 99.9 189.1 1.5e-11 44.5 23.7 5.8 1 1 4 5 5 5 5 Nucleoporin FG repeat region HisKA_2 PF07568.7 EIW79626.1 - 0.65 9.8 5.1 0.89 9.4 2.5 2.0 2 0 0 2 2 2 0 Histidine kinase HWE_HK PF07536.9 EIW79626.1 - 0.67 10.4 6.8 2.8 8.4 2.0 2.9 2 0 0 2 2 2 0 HWE histidine kinase DUF4140 PF13600.1 EIW79626.1 - 9.4 6.7 12.0 0.056 13.8 0.6 2.8 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) WD40 PF00400.27 EIW79627.1 - 6.6e-36 120.9 0.8 3.8e-08 32.9 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EIW79627.1 - 8.2e-06 25.6 0.1 0.012 15.3 0.0 3.2 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EIW79627.1 - 0.0028 16.5 0.0 1.4 7.6 0.0 2.4 2 1 0 2 2 2 2 Coatomer WD associated region PD40 PF07676.7 EIW79627.1 - 0.011 15.4 0.3 1.4 8.7 0.0 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 EIW79627.1 - 0.12 11.7 1.3 28 4.1 0.1 3.6 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature eIF-5_eIF-2B PF01873.12 EIW79628.1 - 2.3e-45 153.2 0.1 3.7e-45 152.6 0.0 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 TF_Zn_Ribbon PF08271.7 EIW79628.1 - 0.006 15.8 0.2 0.013 14.8 0.1 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding zf-HYPF PF07503.7 EIW79628.1 - 0.072 12.5 0.1 12 5.4 0.0 2.7 2 0 0 2 2 2 0 HypF finger ATP-synt PF00231.14 EIW79629.1 - 1.2e-72 244.7 5.3 1.3e-72 244.5 3.7 1.0 1 0 0 1 1 1 1 ATP synthase Hexokinase_2 PF03727.11 EIW79630.1 - 3.8e-80 268.6 0.0 5.1e-80 268.1 0.0 1.1 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EIW79630.1 - 1.8e-69 233.2 0.0 4.7e-69 231.8 0.0 1.6 2 0 0 2 2 2 1 Hexokinase Ribosomal_L14 PF00238.14 EIW79631.1 - 1.5e-42 144.1 1.5 1.7e-42 144.0 1.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Thaumatin PF00314.12 EIW79632.1 - 3.9e-12 46.0 11.2 4.9e-12 45.7 7.8 1.2 1 0 0 1 1 1 1 Thaumatin family Porin_4 PF13609.1 EIW79632.1 - 0.011 15.2 1.9 0.011 15.2 1.3 1.6 2 0 0 2 2 2 0 Gram-negative porin FAD-oxidase_C PF02913.14 EIW79633.1 - 2.2e-55 187.7 0.0 3.7e-55 186.9 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EIW79633.1 - 2.4e-30 104.8 0.0 4.5e-30 103.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain SCF PF02404.10 EIW79633.1 - 0.32 10.1 4.0 0.5 9.5 2.8 1.2 1 0 0 1 1 1 0 Stem cell factor ICE2 PF08426.5 EIW79634.1 - 6.5e-05 21.7 7.8 9.4e-05 21.1 5.4 1.3 1 0 0 1 1 1 1 ICE2 Na_Ca_ex PF01699.19 EIW79634.1 - 2.3 7.7 16.4 0.79 9.3 3.8 2.4 2 0 0 2 2 2 0 Sodium/calcium exchanger protein PHZA_PHZB PF03284.8 EIW79635.1 - 0.00059 18.9 0.0 0.00082 18.5 0.0 1.2 1 0 0 1 1 1 1 Phenazine biosynthesis protein A/B DUF543 PF04418.7 EIW79637.1 - 9.4e-28 95.9 0.2 1.1e-27 95.8 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF543) zf-C2HC_2 PF13913.1 EIW79637.1 - 0.14 11.8 0.2 0.26 10.9 0.1 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type BRO1 PF03097.13 EIW79638.1 - 5.9e-114 380.7 0.2 1.2e-113 379.7 0.1 1.5 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EIW79638.1 - 2.6e-60 203.9 5.8 2.6e-60 203.9 4.0 2.0 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV EF-hand_1 PF00036.27 EIW79639.1 - 0.0065 15.6 0.0 0.021 14.1 0.0 1.9 1 0 0 1 1 1 1 EF hand DUF167 PF02594.11 EIW79639.1 - 0.014 15.3 0.8 0.044 13.7 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised ACR, YggU family COG1872 Yip1 PF04893.12 EIW79640.1 - 7.2e-08 32.1 18.8 9.7e-08 31.6 13.1 1.3 1 0 0 1 1 1 1 Yip1 domain AA_permease_2 PF13520.1 EIW79641.1 - 6.8e-48 163.2 40.0 8.4e-48 162.9 27.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIW79641.1 - 1.2e-09 37.0 35.3 1.7e-09 36.5 24.5 1.1 1 0 0 1 1 1 1 Amino acid permease 5_3_exonuc_N PF02739.11 EIW79641.1 - 0.14 11.5 0.1 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 5'-3' exonuclease, N-terminal resolvase-like domain Peroxidase_2 PF01328.12 EIW79642.1 - 1.2e-17 63.5 0.3 1.8e-17 62.9 0.2 1.4 1 1 0 1 1 1 1 Peroxidase, family 2 ThiF PF00899.16 EIW79643.1 - 7.5e-37 126.1 0.1 1.3e-36 125.4 0.1 1.4 1 0 0 1 1 1 1 ThiF family NAD_binding_7 PF13241.1 EIW79643.1 - 0.00038 20.6 0.1 0.0008 19.6 0.1 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Saccharop_dh PF03435.13 EIW79643.1 - 0.00039 19.5 0.3 0.0017 17.4 0.2 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase DAO PF01266.19 EIW79643.1 - 0.0033 16.3 0.7 0.026 13.4 0.1 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EIW79643.1 - 0.021 14.4 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EIW79643.1 - 0.16 11.0 0.3 0.22 10.5 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.11 EIW79643.1 - 0.18 11.2 0.0 0.32 10.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Endotoxin_N PF03945.9 EIW79645.1 - 0.031 13.6 0.2 0.052 12.9 0.2 1.3 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain Imm8 PF15560.1 EIW79645.1 - 0.058 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Immunity protein 8 PaaSYMP PF14738.1 EIW79645.1 - 0.7 9.6 7.7 1.4 8.6 0.3 2.4 2 0 0 2 2 2 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 F-box-like PF12937.2 EIW79647.1 - 0.00058 19.5 0.0 0.0017 18.0 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW79647.1 - 0.0018 17.8 0.1 0.0069 16.0 0.1 2.1 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.1 EIW79647.1 - 0.018 14.7 1.9 0.19 11.5 0.3 2.8 1 1 1 2 2 2 0 Leucine rich repeat LRR_4 PF12799.2 EIW79647.1 - 0.17 11.5 2.0 0.66 9.6 0.8 2.4 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Sds3 PF08598.6 EIW79649.1 - 2.7e-17 63.0 0.0 2.7e-17 63.0 0.0 2.7 2 0 0 2 2 2 1 Sds3-like Plus-3 PF03126.13 EIW79650.1 - 1.5e-23 82.9 0.0 5.7e-23 81.0 0.0 2.1 1 0 0 1 1 1 1 Plus-3 domain WD40 PF00400.27 EIW79651.1 - 3.5e-30 102.7 17.7 8.2e-11 41.3 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Sof1 PF04158.9 EIW79651.1 - 4.3e-27 93.9 10.4 7.4e-27 93.2 7.2 1.4 1 0 0 1 1 1 1 Sof1-like domain Vps26 PF03643.10 EIW79653.1 - 1.1e-129 431.1 3.4 1.2e-129 430.9 2.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EIW79653.1 - 0.00044 20.1 0.4 0.14 12.0 0.1 3.4 1 1 2 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EIW79653.1 - 0.04 14.0 0.2 0.47 10.5 0.1 2.6 1 1 1 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Gln-synt_N PF03951.14 EIW79653.1 - 0.061 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain AAA_5 PF07728.9 EIW79654.1 - 5.4e-69 230.2 0.0 3.6e-31 107.7 0.0 3.7 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) VWA_2 PF13519.1 EIW79654.1 - 0.0022 18.1 0.0 0.0041 17.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain AAA_3 PF07726.6 EIW79654.1 - 0.011 15.2 0.0 0.11 12.0 0.0 2.6 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EIW79654.1 - 0.025 14.4 0.1 0.54 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain (Cdc48 subfamily) CbbQ_C PF08406.5 EIW79654.1 - 0.052 13.5 0.2 0.89 9.5 0.3 2.4 2 0 0 2 2 2 0 CbbQ/NirQ/NorQ C-terminal AAA_22 PF13401.1 EIW79654.1 - 0.097 12.8 0.0 0.52 10.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain vWA-TerF-like PF10138.4 EIW79654.1 - 0.12 12.2 0.0 0.39 10.5 0.0 1.8 2 0 0 2 2 2 0 vWA found in TerF C terminus AAA_32 PF13654.1 EIW79654.1 - 0.12 10.9 0.4 1.8 7.0 0.3 2.0 2 0 0 2 2 2 0 AAA domain GNVR PF13807.1 EIW79654.1 - 0.17 11.6 0.0 0.4 10.4 0.0 1.5 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase NUDIX PF00293.23 EIW79655.1 - 0.0065 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain TB2_DP1_HVA22 PF03134.14 EIW79656.1 - 1.4e-26 92.0 5.7 1.9e-26 91.6 4.0 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family DUF2413 PF10310.4 EIW79656.1 - 1.5 7.5 4.5 2.1 7.0 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) Fungal_trans PF04082.13 EIW79658.1 - 2.7e-20 72.3 0.0 7.5e-20 70.8 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW79658.1 - 0.00016 21.5 14.1 0.00029 20.6 9.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cellulose_synt PF03552.9 EIW79658.1 - 7.9 4.6 3.4 12 4.0 2.3 1.1 1 0 0 1 1 1 0 Cellulose synthase CLN3 PF02487.12 EIW79659.1 - 1.5e-63 215.0 1.7 4.4e-61 206.8 1.2 2.5 1 1 0 1 1 1 1 CLN3 protein DEAD PF00270.24 EIW79660.1 - 3e-44 150.4 0.0 6.9e-44 149.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EIW79660.1 - 2.5e-26 90.9 0.1 5.7e-26 89.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EIW79660.1 - 5.7e-19 67.7 0.0 1.4e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Pkinase PF00069.20 EIW79661.1 - 1.6e-07 30.7 0.0 2.5e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW79661.1 - 0.002 17.2 0.0 0.003 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW79661.1 - 0.0083 15.8 0.4 0.024 14.3 0.2 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family PT-TG PF14449.1 EIW79661.1 - 0.022 14.5 0.0 0.043 13.5 0.0 1.4 1 0 0 1 1 1 0 Pre-toxin TG DUF2013 PF09431.5 EIW79662.1 - 1.6e-46 157.5 3.2 1.6e-46 157.5 2.2 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2013) VIT1 PF01988.14 EIW79663.1 - 3.5e-69 232.5 7.7 4.1e-69 232.3 5.4 1.0 1 0 0 1 1 1 1 VIT family DUF4064 PF13273.1 EIW79663.1 - 0.013 15.6 3.6 4.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) zf-H2C2 PF09337.5 EIW79663.1 - 0.14 11.6 0.1 4.5 6.7 0.0 2.3 2 0 0 2 2 2 0 His(2)-Cys(2) zinc finger His_Phos_2 PF00328.17 EIW79664.1 - 5.7e-07 29.1 0.5 1.6e-05 24.4 0.4 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NAD_binding_6 PF08030.7 EIW79665.1 - 4.5e-36 124.1 0.0 8e-36 123.2 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EIW79665.1 - 1.8e-24 85.6 0.0 4e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EIW79665.1 - 7.2e-15 55.1 8.1 7.2e-15 55.1 5.6 2.0 1 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EIW79665.1 - 7.3e-05 22.8 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EIW79665.1 - 0.14 12.7 0.0 2.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain ATP_bind_3 PF01171.15 EIW79666.1 - 7.4e-27 94.0 0.0 1.3e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 PP-loop family Epimerase PF01370.16 EIW79667.1 - 5.9e-20 71.7 0.0 8.2e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW79667.1 - 5.1e-15 55.9 0.1 9.9e-15 55.0 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIW79667.1 - 4.4e-12 45.2 0.0 7.1e-12 44.5 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EIW79667.1 - 1.4e-07 30.7 0.3 2e-06 26.8 0.2 2.0 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EIW79667.1 - 1e-05 24.9 0.0 2.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EIW79667.1 - 2.8e-05 24.1 0.3 0.00016 21.6 0.2 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW79667.1 - 0.0043 16.7 1.3 0.024 14.2 0.9 2.1 1 1 0 1 1 1 1 KR domain UPF0020 PF01170.13 EIW79667.1 - 0.083 12.4 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Velvet PF11754.3 EIW79668.1 - 2.8e-23 82.6 0.0 5.4e-23 81.6 0.0 1.4 1 1 0 1 1 1 1 Velvet factor Glyco_hydro_71 PF03659.9 EIW79669.1 - 1.6e-97 326.4 12.2 1.9e-97 326.1 8.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glucan_synthase PF02364.10 EIW79670.1 - 0 1371.5 0.0 0 1371.1 0.0 1.2 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EIW79670.1 - 1.3e-38 131.5 0.0 3.2e-38 130.2 0.0 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 YukC PF10140.4 EIW79671.1 - 0.015 13.9 0.4 0.02 13.5 0.3 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC ABC2_membrane_3 PF12698.2 EIW79671.1 - 0.016 14.2 0.0 0.017 14.2 0.0 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4464 PF14713.1 EIW79671.1 - 0.039 13.3 0.2 0.055 12.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4464) DUF4064 PF13273.1 EIW79671.1 - 0.058 13.5 0.8 0.1 12.6 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Tmemb_170 PF10190.4 EIW79671.1 - 0.089 12.8 6.4 0.55 10.3 0.7 2.3 1 1 1 2 2 2 0 Putative transmembrane protein 170 Viral_Beta_CD PF04530.7 EIW79671.1 - 0.16 12.0 0.3 0.31 11.2 0.2 1.5 1 0 0 1 1 1 0 Viral Beta C/D like family COX2_TM PF02790.10 EIW79671.1 - 0.23 11.4 1.6 0.89 9.5 0.2 2.1 2 0 0 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain DUF4293 PF14126.1 EIW79671.1 - 0.33 10.8 2.8 0.44 10.4 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) Adeno_E3_CR2 PF02439.10 EIW79671.1 - 2.6 7.6 5.4 14 5.3 0.5 2.3 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Iso_dh PF00180.15 EIW79672.1 - 6.5e-72 242.3 0.0 8.1e-72 242.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PNP_UDP_1 PF01048.15 EIW79674.1 - 7.1e-35 120.0 0.2 8.7e-35 119.7 0.1 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily EutN_CcmL PF03319.8 EIW79674.1 - 0.064 13.6 0.6 0.15 12.4 0.2 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutN/carboxysome RTA1 PF04479.8 EIW79675.1 - 2.3e-37 128.6 2.4 2.3e-37 128.6 1.6 1.3 2 0 0 2 2 2 1 RTA1 like protein PMP22_Claudin PF00822.15 EIW79675.1 - 0.02 14.5 0.3 0.02 14.5 0.2 2.3 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family DUF4131 PF13567.1 EIW79675.1 - 0.18 11.1 1.7 0.54 9.6 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) ICMT PF04140.9 EIW79676.1 - 4.5e-14 52.4 0.5 1.5e-13 50.7 0.1 2.0 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIW79676.1 - 8.4e-13 48.3 2.2 1.7e-11 44.1 1.5 2.3 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EIW79676.1 - 0.00078 18.0 0.1 0.0013 17.3 0.1 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EIW79676.1 - 0.055 12.7 0.6 0.086 12.1 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Acyl-CoA_dh_1 PF00441.19 EIW79678.1 - 0.00047 20.2 0.3 0.0012 18.9 0.2 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Pkinase PF00069.20 EIW79679.1 - 1.6e-73 247.0 0.0 2.7e-73 246.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW79679.1 - 1.2e-32 112.9 0.0 2.1e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW79679.1 - 8e-05 21.7 0.0 0.00018 20.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EIW79679.1 - 0.00024 20.5 0.5 0.00048 19.5 0.0 1.8 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EIW79679.1 - 0.00056 19.0 0.0 0.0012 17.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW79679.1 - 0.0049 16.6 0.0 0.018 14.7 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family DAO PF01266.19 EIW79683.1 - 3.8e-56 190.5 0.4 4.9e-56 190.1 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIW79683.1 - 1.5e-06 28.1 0.1 0.0093 15.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW79683.1 - 6.4e-05 22.8 0.1 0.00023 21.1 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GMC_oxred_N PF00732.14 EIW79683.1 - 7.4e-05 22.0 0.1 0.025 13.7 0.0 2.3 2 0 0 2 2 2 2 GMC oxidoreductase Trp_halogenase PF04820.9 EIW79683.1 - 0.0012 17.5 0.3 0.078 11.5 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.22 EIW79683.1 - 0.0022 18.3 0.2 0.008 16.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIW79683.1 - 0.0026 17.5 0.1 0.31 10.7 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EIW79683.1 - 0.0069 15.2 0.2 0.17 10.7 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EIW79683.1 - 0.0096 14.8 0.0 0.64 8.8 0.0 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 EIW79683.1 - 0.015 14.3 0.1 0.066 12.2 0.0 2.0 2 0 0 2 2 2 0 Thi4 family Saccharop_dh PF03435.13 EIW79683.1 - 0.033 13.1 0.1 0.052 12.5 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase FAD_binding_3 PF01494.14 EIW79683.1 - 0.06 12.3 0.0 2.9 6.8 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain WH1 PF00568.18 EIW79684.1 - 7.7e-08 32.0 0.3 4.5e-07 29.5 0.2 1.9 1 1 0 1 1 1 1 WH1 domain PBD PF00786.23 EIW79684.1 - 0.12 12.8 0.2 0.27 11.6 0.1 1.7 1 1 0 1 1 1 0 P21-Rho-binding domain Pyr_redox_2 PF07992.9 EIW79685.1 - 1.2e-26 93.7 0.0 7.8e-26 91.1 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW79685.1 - 2.1e-11 44.0 0.1 1.2e-10 41.5 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW79685.1 - 0.00035 20.6 0.1 0.0092 16.0 0.0 2.9 2 1 2 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase CytB6-F_Fe-S PF08802.5 EIW79685.1 - 0.032 14.2 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit Cupin_2 PF07883.6 EIW79686.1 - 9.3e-08 31.4 0.0 7e-07 28.6 0.0 2.0 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 EIW79686.1 - 8.4e-06 25.2 0.0 1.5e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Cupin AraC_binding PF02311.14 EIW79686.1 - 0.0021 17.7 0.0 0.0053 16.4 0.0 1.6 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_6 PF12852.2 EIW79686.1 - 0.0062 16.1 0.0 0.0076 15.8 0.0 1.1 1 0 0 1 1 1 1 Cupin ARD PF03079.9 EIW79686.1 - 0.017 15.0 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 ARD/ARD' family SYF2 PF08231.7 EIW79687.1 - 9.9e-48 162.1 15.6 9.9e-48 162.1 10.8 2.2 2 1 0 2 2 2 1 SYF2 splicing factor 5_nucleotid PF05761.9 EIW79687.1 - 0.89 7.9 10.9 49 2.2 7.6 2.5 1 1 0 1 1 1 0 5' nucleotidase family AA_permease PF00324.16 EIW79688.1 - 3.9e-102 342.0 48.9 4.7e-102 341.8 33.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIW79688.1 - 2.3e-31 108.8 52.2 3e-31 108.4 36.2 1.1 1 0 0 1 1 1 1 Amino acid permease MCM PF00493.18 EIW79689.1 - 1.4e-130 434.9 0.0 1.9e-130 434.5 0.0 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EIW79689.1 - 1.2e-21 77.4 0.0 8.1e-21 74.7 0.0 2.4 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 EIW79689.1 - 3.6e-08 33.2 0.0 2e-07 30.8 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EIW79689.1 - 6.1e-08 32.0 0.0 2.8e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EIW79689.1 - 1.6e-05 24.5 0.1 0.00033 20.2 0.0 2.6 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EIW79689.1 - 0.00014 21.3 0.1 0.58 9.6 0.0 3.4 3 0 0 3 3 3 2 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EIW79689.1 - 0.051 13.6 0.0 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 EIW79689.1 - 0.064 13.4 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_32 PF13654.1 EIW79689.1 - 0.33 9.5 1.3 0.48 9.0 0.3 1.7 2 0 0 2 2 2 0 AAA domain ORC3_N PF07034.6 EIW79690.1 - 4.8e-26 91.5 0.0 9e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus GPI-anchored PF10342.4 EIW79691.1 - 0.00047 20.5 0.3 0.00063 20.1 0.2 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Mito_fiss_Elm1 PF06258.6 EIW79691.1 - 0.015 14.2 0.0 0.019 13.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission ELM1 Lsr2 PF11774.3 EIW79691.1 - 0.049 13.5 0.0 0.057 13.3 0.0 1.1 1 0 0 1 1 1 0 Lsr2 RNA_bind PF08675.6 EIW79691.1 - 0.1 12.6 0.1 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 RNA binding domain Smg4_UPF3 PF03467.10 EIW79692.1 - 2.7e-33 115.4 0.1 2.7e-33 115.4 0.1 2.2 2 0 0 2 2 2 1 Smg-4/UPF3 family DUF4121 PF13497.1 EIW79692.1 - 0.15 11.0 0.0 0.23 10.4 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) MFS_1 PF07690.11 EIW79693.1 - 8.5e-50 169.4 30.9 1.8e-45 155.1 15.0 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW79693.1 - 8.5e-13 47.6 9.6 8.5e-13 47.6 6.6 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EIW79693.1 - 2.9e-12 45.5 6.6 5.2e-12 44.7 4.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 EIW79693.1 - 8.2e-06 24.5 25.0 0.00038 19.0 1.3 3.5 2 2 1 3 3 3 2 Vacuole effluxer Atg22 like MFS_2 PF13347.1 EIW79693.1 - 9e-06 24.3 6.5 9e-06 24.3 4.5 3.0 3 1 1 4 4 4 2 MFS/sugar transport protein MFS_3 PF05977.8 EIW79693.1 - 3.3e-05 22.2 5.6 3.3e-05 22.2 3.9 2.2 3 0 0 3 3 3 1 Transmembrane secretion effector MFS_1_like PF12832.2 EIW79693.1 - 0.017 14.9 0.2 0.017 14.9 0.1 2.0 2 0 0 2 2 2 0 MFS_1 like family OATP PF03137.15 EIW79693.1 - 0.1 10.6 4.4 0.067 11.2 1.4 1.9 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4131 PF13567.1 EIW79693.1 - 1.6 8.0 13.3 21 4.4 1.6 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) GPI-anchored PF10342.4 EIW79695.1 - 8.2e-09 35.8 0.8 8.2e-09 35.8 0.5 3.1 3 1 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family U3_assoc_6 PF08640.6 EIW79697.1 - 0.018 14.8 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 MMS19_C PF12460.3 EIW79697.1 - 0.11 11.1 0.0 0.22 10.2 0.0 1.4 1 0 0 1 1 1 0 RNAPII transcription regulator C-terminal CCDC32 PF14989.1 EIW79704.1 - 0.045 13.5 0.0 0.074 12.8 0.0 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing 32 DDE_1 PF03184.14 EIW79705.1 - 4.8e-07 29.1 0.0 5.8e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIW79705.1 - 0.008 15.9 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease LRR_8 PF13855.1 EIW79706.1 - 1.5e-05 24.6 0.1 0.35 10.6 0.0 4.0 3 1 0 3 3 3 3 Leucine rich repeat DUF2890 PF11081.3 EIW79707.1 - 0.046 13.7 0.4 0.046 13.7 0.3 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) GTP1_OBG PF01018.17 EIW79708.1 - 5e-34 117.2 4.2 2.5e-24 85.7 1.0 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EIW79708.1 - 9.8e-17 60.9 0.0 5.9e-16 58.4 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EIW79708.1 - 2.6e-05 24.1 0.0 4.6e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Dynamin family FeoB_N PF02421.13 EIW79708.1 - 0.00012 21.4 0.0 0.00077 18.7 0.0 2.2 3 0 0 3 3 3 1 Ferrous iron transport protein B Miro PF08477.8 EIW79708.1 - 0.00028 21.3 0.0 1.1 9.7 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein Arf PF00025.16 EIW79708.1 - 0.0025 17.0 0.1 0.86 8.8 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family cobW PF02492.14 EIW79708.1 - 0.0047 16.3 0.1 1.4 8.2 0.0 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.22 EIW79708.1 - 0.0075 15.7 0.0 3.8 6.9 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EIW79708.1 - 0.014 16.1 0.5 1.9 9.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EIW79708.1 - 0.016 14.0 0.4 0.3 9.8 0.1 2.3 2 0 0 2 2 2 0 ArgK protein ABC_tran PF00005.22 EIW79708.1 - 0.042 14.1 0.0 0.085 13.1 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 EIW79708.1 - 0.17 12.1 0.7 0.29 11.4 0.0 1.9 2 0 0 2 2 1 0 AAA domain Thymidylat_synt PF00303.14 EIW79709.1 - 6e-102 340.2 0.0 6.7e-102 340.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase MoCF_biosynth PF00994.19 EIW79710.1 - 4e-34 117.1 0.0 6e-34 116.5 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain HD_4 PF13328.1 EIW79710.1 - 0.0044 16.7 0.0 0.0077 15.9 0.0 1.4 1 0 0 1 1 1 1 HD domain BTB PF00651.26 EIW79711.1 - 2.4e-09 37.1 0.0 4e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain YyzF PF14116.1 EIW79711.1 - 0.15 12.0 0.7 0.38 10.7 0.0 2.0 2 0 0 2 2 2 0 YyzF-like protein PDCD2_C PF04194.8 EIW79712.1 - 0.092 12.3 0.3 0.18 11.3 0.0 1.6 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain Peptidase_M16 PF00675.15 EIW79712.1 - 0.12 12.0 0.0 0.34 10.6 0.0 1.7 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) HSP70 PF00012.15 EIW79714.1 - 1.5e-92 310.4 0.0 2e-89 300.1 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EIW79714.1 - 1.2e-15 56.9 0.2 2.1e-15 56.1 0.1 1.3 1 0 0 1 1 1 1 MreB/Mbl protein FtsA PF14450.1 EIW79714.1 - 0.014 15.1 2.2 0.24 11.2 0.0 3.1 2 2 0 2 2 2 0 Cell division protein FtsA StbA PF06406.6 EIW79714.1 - 0.019 13.8 0.4 0.055 12.4 0.2 1.8 1 1 2 3 3 3 0 StbA protein PilM_2 PF11104.3 EIW79714.1 - 0.021 13.7 0.0 0.037 12.9 0.0 1.3 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; Abhydrolase_6 PF12697.2 EIW79715.1 - 3.8e-20 72.7 0.3 3.8e-20 72.7 0.2 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW79715.1 - 0.00056 19.6 0.0 0.0017 18.1 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW79715.1 - 0.0026 17.3 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EIW79715.1 - 0.023 14.2 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) ADH_N PF08240.7 EIW79718.1 - 7.8e-26 89.9 2.2 9.8e-26 89.6 0.9 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW79718.1 - 3.9e-08 32.9 0.1 4.5e-07 29.4 0.1 2.3 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EIW79718.1 - 5.3e-08 32.3 0.1 1.1e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated HI0933_like PF03486.9 EIW79718.1 - 0.036 12.5 0.1 0.053 11.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 EIW79719.1 - 8.5e-14 51.3 0.0 1.2e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EIW79719.1 - 0.13 12.2 0.1 0.32 11.0 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HLH PF00010.21 EIW79720.1 - 4.5e-11 42.2 0.5 9.2e-11 41.2 0.4 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Fungal_trans PF04082.13 EIW79721.1 - 3.3e-17 62.2 0.0 4.6e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain VARLMGL PF14383.1 EIW79721.1 - 0.052 12.7 1.0 0.36 10.0 0.1 2.3 2 0 0 2 2 2 0 DUF761-associated sequence motif Zn_clus PF00172.13 EIW79722.1 - 2.5e-06 27.2 6.6 3.1e-06 26.9 4.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RseC_MucC PF04246.7 EIW79722.1 - 0.081 12.4 1.4 0.088 12.3 1.0 1.1 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC MamL-1 PF09596.5 EIW79722.1 - 1.1 9.0 4.7 2.7 7.8 3.2 1.8 1 1 0 1 1 1 0 MamL-1 domain Peptidase_S24 PF00717.18 EIW79723.1 - 5.4e-09 35.5 0.0 8.1e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like TPR_14 PF13428.1 EIW79724.1 - 1.3e-08 34.6 1.1 0.029 14.9 0.0 5.3 2 1 3 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EIW79724.1 - 2.6e-08 33.4 0.9 0.0015 18.1 0.0 3.4 3 1 0 3 3 3 2 TPR repeat TPR_19 PF14559.1 EIW79724.1 - 5.6e-08 33.0 1.4 0.089 13.1 0.1 3.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIW79724.1 - 6.5e-08 33.0 2.5 0.00014 22.3 0.0 4.4 2 2 2 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIW79724.1 - 1.7e-06 27.4 0.1 0.026 14.3 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIW79724.1 - 7.1e-06 25.5 0.2 0.082 12.8 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIW79724.1 - 0.00011 21.5 2.9 0.16 11.6 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 EIW79724.1 - 0.0026 17.5 3.6 2.4 8.0 0.0 3.6 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIW79724.1 - 0.0029 17.9 0.4 49 4.7 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat ChAPs PF09295.5 EIW79724.1 - 0.023 13.4 0.0 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_12 PF13424.1 EIW79724.1 - 0.036 13.9 3.6 17 5.4 0.1 4.0 1 1 3 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EIW79724.1 - 0.042 13.6 0.2 2.1 8.3 0.0 3.5 4 1 0 4 4 4 0 Tetratricopeptide repeat Pterin_bind PF00809.17 EIW79725.1 - 4.4e-50 169.9 0.0 6.8e-50 169.3 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 EIW79725.1 - 7.9e-33 112.8 0.0 1.4e-31 108.8 0.0 2.4 1 1 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 EIW79725.1 - 3.5e-27 94.8 1.3 1.5e-17 63.7 0.0 2.6 3 0 0 3 3 3 2 Dihydroneopterin aldolase Ribosomal_S30 PF04758.9 EIW79726.1 - 1.1e-30 105.1 7.1 1.2e-30 105.0 4.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 FAD_binding_3 PF01494.14 EIW79727.1 - 4.4e-20 72.0 0.5 8.1e-19 67.8 0.3 2.1 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EIW79727.1 - 0.018 13.9 0.0 0.066 12.0 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_8 PF13450.1 EIW79727.1 - 0.11 12.5 0.1 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain LEA_6 PF10714.4 EIW79728.1 - 0.053 13.3 3.8 0.047 13.4 1.9 1.4 1 1 0 1 1 1 0 Late embryogenesis abundant protein 18 Campylo_MOMP PF05538.6 EIW79728.1 - 0.055 11.8 0.5 0.069 11.5 0.3 1.1 1 0 0 1 1 1 0 Campylobacter major outer membrane protein F-box-like PF12937.2 EIW79729.1 - 9e-08 31.7 0.0 2.5e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 F-box-like Abhydrolase_6 PF12697.2 EIW79730.1 - 3e-08 33.8 0.2 3.2e-07 30.4 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family Mito_carr PF00153.22 EIW79731.1 - 1.7e-15 56.5 0.7 2.1e-15 56.1 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein Cullin_Nedd8 PF10557.4 EIW79731.1 - 0.0067 16.2 0.2 0.01 15.6 0.2 1.4 1 1 0 1 1 1 1 Cullin protein neddylation domain Mito_carr PF00153.22 EIW79732.1 - 4e-23 80.9 0.1 4.5e-11 42.2 0.0 2.1 2 0 0 2 2 2 2 Mitochondrial carrier protein BTB PF00651.26 EIW79733.1 - 1.1e-09 38.2 0.0 2.6e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EIW79734.1 - 6.5e-10 38.9 0.0 1e-09 38.3 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain SF-assemblin PF06705.6 EIW79735.1 - 0.12 11.4 4.9 0.19 10.8 3.4 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin GAS PF13851.1 EIW79735.1 - 3.3 6.8 2.8 7.2 5.7 1.9 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding COMP PF11598.3 EIW79736.1 - 0.54 10.3 4.7 0.17 11.9 0.2 2.1 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein adh_short_C2 PF13561.1 EIW79737.1 - 2.6e-23 83.0 1.2 1.7e-21 77.1 0.8 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIW79737.1 - 1.1e-20 74.2 1.1 3.5e-18 66.0 0.2 2.5 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIW79737.1 - 6e-09 35.8 0.0 1.5e-08 34.5 0.0 1.8 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW79737.1 - 0.0029 17.1 0.1 0.024 14.0 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW79737.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding 3Beta_HSD PF01073.14 EIW79737.1 - 0.037 12.7 0.1 0.059 12.0 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EIW79737.1 - 0.044 13.0 0.1 0.075 12.2 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family N_Asn_amidohyd PF14736.1 EIW79738.1 - 0.019 13.8 0.0 0.029 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase LRR_4 PF12799.2 EIW79738.1 - 0.41 10.3 2.0 9.9 5.9 0.0 3.6 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) FMN_dh PF01070.13 EIW79739.1 - 1.9e-105 352.6 0.0 2.3e-105 352.3 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 EIW79739.1 - 4.5e-06 26.0 0.9 6.6e-06 25.5 0.6 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EIW79739.1 - 5.3e-05 22.2 0.4 0.00015 20.7 0.2 1.7 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EIW79739.1 - 0.00016 20.7 0.1 0.00024 20.1 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.16 EIW79739.1 - 0.00057 18.9 0.1 0.0032 16.4 0.0 2.1 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase ThiG PF05690.9 EIW79739.1 - 0.0057 15.7 0.6 1.2 8.1 0.1 2.3 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EIW79739.1 - 0.092 12.0 0.2 0.22 10.7 0.1 1.6 1 1 0 1 1 1 0 Histidine biosynthesis protein Complex1_LYR_1 PF13232.1 EIW79740.1 - 6e-10 39.1 1.5 7.6e-10 38.8 1.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EIW79740.1 - 1.5e-06 27.8 0.6 1.9e-06 27.5 0.4 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) HIG_1_N PF04588.8 EIW79741.1 - 1.4e-21 75.9 0.4 1.8e-21 75.5 0.3 1.1 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DJ-1_PfpI PF01965.19 EIW79741.1 - 0.041 13.3 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 DJ-1/PfpI family SNO PF01174.14 EIW79741.1 - 0.071 12.7 0.0 0.087 12.4 0.0 1.2 1 0 0 1 1 1 0 SNO glutamine amidotransferase family Glyco_hydro_31 PF01055.21 EIW79742.1 - 9.4e-80 268.5 9.8 2.6e-79 267.1 6.8 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EIW79742.1 - 2.3e-08 33.7 0.1 6.2e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like Terpene_synth_C PF03936.11 EIW79743.1 - 3.4e-16 59.2 0.0 4.8e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain BTB PF00651.26 EIW79744.1 - 2.1e-19 69.5 0.0 3.1e-10 40.0 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain Cytochrome_CBB3 PF13442.1 EIW79744.1 - 0.026 14.6 0.1 2.3 8.4 0.0 3.0 3 0 0 3 3 3 0 Cytochrome C oxidase, cbb3-type, subunit III DUF2673 PF10880.3 EIW79744.1 - 2.5 8.2 4.6 20 5.3 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) BTB PF00651.26 EIW79745.1 - 2.2e-09 37.3 0.0 4.3e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 EIW79745.1 - 0.14 12.2 0.0 0.4 10.8 0.0 1.8 2 0 0 2 2 2 0 Skp1 family, tetramerisation domain BTB PF00651.26 EIW79746.1 - 6.1e-13 48.7 0.1 9.7e-13 48.0 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF2673 PF10880.3 EIW79746.1 - 0.95 9.5 3.2 0.59 10.2 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2673) BTB PF00651.26 EIW79747.1 - 3e-12 46.5 0.0 1.1e-11 44.7 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain BTB PF00651.26 EIW79748.1 - 1e-09 38.3 0.0 3.2e-09 36.7 0.0 1.7 2 0 0 2 2 2 1 BTB/POZ domain Skp1_POZ PF03931.10 EIW79748.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Thr_synth_N PF14821.1 EIW79749.1 - 2.3e-27 94.8 0.0 8.1e-27 93.0 0.0 2.0 2 0 0 2 2 2 1 Threonine synthase N terminus PALP PF00291.20 EIW79749.1 - 3.2e-15 56.1 0.0 2.3e-14 53.3 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme STAG PF08514.6 EIW79750.1 - 4.8e-27 94.0 0.0 4.8e-26 90.7 0.0 2.5 2 0 0 2 2 2 1 STAG domain HEAT PF02985.17 EIW79750.1 - 0.057 13.5 7.4 23 5.4 0.0 5.6 6 0 0 6 6 6 0 HEAT repeat Terpene_synth_C PF03936.11 EIW79751.1 - 2.1e-10 40.3 0.0 3e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain DUF1221 PF06760.6 EIW79751.1 - 0.13 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1221) adh_short PF00106.20 EIW79752.1 - 2.5e-13 50.2 0.7 3.8e-13 49.6 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIW79752.1 - 3.5e-07 30.0 0.1 8.2e-07 28.8 0.1 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIW79752.1 - 1.2e-06 28.4 0.2 0.0016 18.2 0.0 2.0 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase DUF4109 PF13397.1 EIW79752.1 - 0.17 12.3 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4109) Prenyltrans PF00432.16 EIW79753.1 - 8.3e-59 194.7 6.6 3.2e-13 48.9 0.1 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EIW79753.1 - 4.1e-32 110.9 0.0 1e-14 54.8 0.0 3.9 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EIW79753.1 - 2.6e-08 33.8 0.0 4.7e-05 23.3 0.0 3.3 1 1 2 3 3 3 2 Prenyltransferase-like E1-E2_ATPase PF00122.15 EIW79754.1 - 2.9e-47 160.6 2.6 2.9e-47 160.6 1.8 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EIW79754.1 - 1.2e-30 106.4 7.1 1.2e-30 106.4 5.0 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EIW79754.1 - 8.9e-28 98.1 0.0 5.2e-27 95.6 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIW79754.1 - 1e-17 64.9 0.0 2.8e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIW79754.1 - 1.4e-16 60.1 0.0 2.7e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EIW79754.1 - 1.8e-08 33.7 0.0 4e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIW79754.1 - 1e-07 31.8 0.7 2e-07 30.8 0.5 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Aminotran_1_2 PF00155.16 EIW79758.1 - 2.6e-40 138.5 0.0 3.1e-40 138.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EIW79758.1 - 9.4e-06 24.1 0.0 0.00019 19.8 0.0 2.2 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EIW79758.1 - 0.11 11.5 0.0 0.22 10.6 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase OKR_DC_1 PF01276.15 EIW79758.1 - 0.15 10.5 0.0 0.32 9.4 0.0 1.5 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain zf-MYND PF01753.13 EIW79759.1 - 3.9e-12 45.8 6.8 9.1e-12 44.6 4.7 1.6 1 0 0 1 1 1 1 MYND finger RNA_Me_trans PF04252.8 EIW79760.1 - 1.5e-38 132.1 0.0 2.2e-38 131.6 0.0 1.2 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase FAD_binding_3 PF01494.14 EIW79761.1 - 4.7e-21 75.2 1.4 2.1e-10 40.2 0.0 2.6 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EIW79761.1 - 3.3e-05 23.8 0.4 8.7e-05 22.4 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EIW79761.1 - 0.0092 14.8 0.0 0.018 13.8 0.0 1.4 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_3 PF13738.1 EIW79761.1 - 0.011 15.8 0.4 0.023 14.7 0.3 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW79761.1 - 0.045 12.6 0.2 0.066 12.0 0.1 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EIW79761.1 - 0.049 13.4 0.1 0.26 11.0 0.2 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EIW79761.1 - 0.061 13.7 0.3 0.14 12.6 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW79761.1 - 0.1 12.4 0.4 0.16 11.8 0.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Cauli_VI PF01693.11 EIW79764.1 - 1.7e-05 24.7 0.2 5.4e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 Caulimovirus viroplasmin zf-B_box PF00643.19 EIW79765.1 - 0.1 12.5 8.9 0.026 14.3 3.3 2.2 2 0 0 2 2 2 0 B-box zinc finger DUF4501 PF14946.1 EIW79767.1 - 0.081 12.3 0.3 0.13 11.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) Trypan_PARP PF05887.6 EIW79768.1 - 2.3e-05 24.2 10.0 5.6e-05 22.9 7.0 1.6 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.20 EIW79769.1 - 1.3e-61 208.0 0.0 2e-61 207.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW79769.1 - 1.2e-42 145.7 0.0 2.8e-42 144.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.3 EIW79769.1 - 1.5e-20 73.4 0.0 2.4e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Kinase-like PF14531.1 EIW79769.1 - 0.00019 20.5 0.0 0.00039 19.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW79769.1 - 0.0011 18.7 3.9 0.0048 16.6 0.1 3.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family Dioxygenase_C PF00775.16 EIW79770.1 - 1.7e-52 177.3 0.0 2.5e-52 176.8 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EIW79770.1 - 7.2e-13 48.3 0.0 2.2e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EIW79770.1 - 0.00035 20.5 0.0 0.0013 18.7 0.0 2.0 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF1389 PF07146.6 EIW79770.1 - 0.14 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1389) Myb_DNA-binding PF00249.26 EIW79774.1 - 2e-07 30.9 0.1 3.7e-07 30.1 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIW79774.1 - 1.8e-05 24.7 0.2 5.2e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Toxin-deaminase PF14424.1 EIW79774.1 - 0.12 12.3 1.7 0.83 9.6 0.0 2.3 2 0 0 2 2 2 0 The BURPS668_1122 family of deaminases DDHD PF02862.12 EIW79774.1 - 6.7 6.4 10.5 0.64 9.7 1.7 2.7 3 0 0 3 3 3 0 DDHD domain DUF373 PF04123.8 EIW79775.1 - 0.74 8.7 7.5 1.2 8.0 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF4233 PF14017.1 EIW79776.1 - 3.9 7.4 9.3 0.42 10.5 2.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) PRCH PF03967.8 EIW79778.1 - 0.021 14.4 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Photosynthetic reaction centre, H-chain N-terminal region DUF2484 PF10658.4 EIW79778.1 - 0.68 10.0 6.5 1 9.5 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2484) Polysacc_synt_4 PF04669.8 EIW79779.1 - 3.4e-22 78.7 2.3 3.3e-21 75.5 1.6 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis DivIC PF04977.10 EIW79779.1 - 2.1 7.8 7.3 1.4 8.4 0.2 2.7 3 0 0 3 3 3 0 Septum formation initiator TIMELESS PF04821.9 EIW79780.1 - 9.4e-47 159.4 0.0 1.9e-46 158.5 0.0 1.5 1 0 0 1 1 1 1 Timeless protein bZIP_1 PF00170.16 EIW79782.1 - 0.00016 21.5 10.2 0.0025 17.7 2.6 2.3 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 EIW79782.1 - 0.0072 16.1 14.8 0.026 14.3 3.4 2.4 2 0 0 2 2 2 2 Basic region leucine zipper HALZ PF02183.13 EIW79782.1 - 0.071 12.8 1.2 0.15 11.7 0.9 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper TSC22 PF01166.13 EIW79782.1 - 0.13 12.2 1.5 0.22 11.5 0.3 1.9 2 0 0 2 2 2 0 TSC-22/dip/bun family DivIC PF04977.10 EIW79782.1 - 0.18 11.3 4.2 0.61 9.6 0.4 2.4 2 0 0 2 2 2 0 Septum formation initiator NYD-SP28_assoc PF14775.1 EIW79782.1 - 0.21 11.2 4.2 0.071 12.8 0.9 1.7 2 0 0 2 2 2 0 Sperm tail C-terminal domain Shugoshin_N PF07558.6 EIW79782.1 - 0.24 11.1 4.4 0.78 9.4 1.3 2.4 2 0 0 2 2 2 0 Shugoshin N-terminal coiled-coil region DUF904 PF06005.7 EIW79782.1 - 0.31 11.3 3.6 0.99 9.7 2.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF904) OPA3 PF07047.7 EIW79782.1 - 4.3 7.1 5.6 1.4 8.6 0.3 2.3 2 0 0 2 2 2 0 Optic atrophy 3 protein (OPA3) AA_permease PF00324.16 EIW79783.1 - 3e-113 378.7 37.1 3.6e-113 378.4 25.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIW79783.1 - 2.7e-31 108.5 39.9 4.3e-31 107.8 27.7 1.3 1 0 0 1 1 1 1 Amino acid permease Hydrolase_6 PF13344.1 EIW79784.1 - 2.7e-29 101.0 0.0 4.4e-29 100.3 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIW79784.1 - 3.4e-16 58.7 0.0 6.8e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EIW79784.1 - 6.4e-12 46.3 0.0 7.9e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIW79784.1 - 7.5e-07 29.5 0.1 0.00013 22.2 0.0 2.5 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.5 EIW79784.1 - 0.0036 16.6 0.0 0.012 14.9 0.0 1.8 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase PIG-F PF06699.6 EIW79785.1 - 6.2e-33 114.3 7.5 6.2e-33 114.3 5.2 2.3 2 1 1 3 3 3 1 GPI biosynthesis protein family Pig-F DUF4064 PF13273.1 EIW79785.1 - 0.0047 16.9 0.9 0.11 12.5 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) PT-TG PF14449.1 EIW79785.1 - 0.1 12.3 0.0 0.4 10.5 0.0 2.0 1 0 0 1 1 1 0 Pre-toxin TG SNARE_assoc PF09335.6 EIW79785.1 - 0.14 12.3 5.7 2 8.6 1.9 3.3 3 0 0 3 3 3 0 SNARE associated Golgi protein Ribosomal_L34e PF01199.13 EIW79786.1 - 6.4e-38 128.8 3.8 8.7e-38 128.4 2.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L34e DUF1428 PF07237.6 EIW79786.1 - 0.11 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) FhuF_C PF11575.3 EIW79786.1 - 4.1 7.1 6.5 7.2 6.3 0.2 2.7 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain Tetraspannin PF00335.15 EIW79789.1 - 0.0017 17.6 3.3 0.0046 16.2 2.3 1.7 1 1 0 1 1 1 1 Tetraspanin family TctB PF07331.6 EIW79789.1 - 0.014 15.0 1.0 0.14 11.7 0.4 2.1 2 0 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family Rhabdo_glycop PF00974.13 EIW79789.1 - 0.04 12.1 0.0 0.06 11.5 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein DUF4444 PF14563.1 EIW79791.1 - 0.017 14.5 0.3 0.15 11.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4444) F-box PF00646.28 EIW79791.1 - 0.088 12.4 0.7 0.33 10.6 0.5 2.1 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 EIW79791.1 - 0.2 11.4 1.9 0.33 10.7 0.1 2.4 2 0 0 2 2 2 0 F-box-like Ribosomal_L31e PF01198.14 EIW79792.1 - 4.3e-34 116.0 1.9 6.9e-34 115.3 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L31e CFEM PF05730.6 EIW79793.1 - 2e-11 43.5 17.5 2.3e-11 43.3 12.1 1.1 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.15 EIW79793.1 - 0.67 10.0 9.6 0.079 12.9 3.5 1.7 2 0 0 2 2 2 0 Gamma-thionin family TIL PF01826.12 EIW79793.1 - 0.84 9.8 11.0 0.85 9.7 7.2 1.5 1 1 0 1 1 1 0 Trypsin Inhibitor like cysteine rich domain CAP59_mtransfer PF11735.3 EIW79794.1 - 1.4e-70 237.2 0.1 1.9e-70 236.8 0.1 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Ion_trans PF00520.26 EIW79794.1 - 0.082 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Ion transport protein RNA_pol_Rpc34 PF05158.7 EIW79795.1 - 2.8e-79 266.6 0.6 1.9e-67 227.7 0.0 2.3 2 0 0 2 2 2 2 RNA polymerase Rpc34 subunit LT-IIB PF06453.6 EIW79795.1 - 0.13 11.9 0.0 0.44 10.2 0.0 1.8 2 0 0 2 2 2 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) DUF936 PF06075.7 EIW79795.1 - 9.4 5.0 36.8 22 3.8 25.5 1.6 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) DUF2207 PF09972.4 EIW79797.1 - 0.023 13.2 0.8 0.031 12.8 0.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ABC2_membrane_3 PF12698.2 EIW79797.1 - 1.3 7.9 16.1 1.7 7.6 11.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Rdx PF10262.4 EIW79798.1 - 0.11 12.5 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Rdx family Asp PF00026.18 EIW79799.1 - 3.9e-80 269.4 10.9 4.7e-80 269.1 7.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW79799.1 - 9.3e-05 22.4 4.0 9.3e-05 22.4 2.8 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIW79799.1 - 0.0013 18.3 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Sec10 PF07393.6 EIW79800.1 - 0.035 12.3 0.0 0.054 11.6 0.0 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec10 LRR_4 PF12799.2 EIW79801.1 - 0.0011 18.4 10.5 0.85 9.3 0.3 5.4 5 1 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW79801.1 - 0.031 14.0 6.0 39 4.1 0.0 4.8 3 1 1 4 4 4 0 Leucine rich repeat DUF3008 PF11450.3 EIW79803.1 - 0.14 12.3 0.0 30 4.8 0.0 3.5 3 1 1 4 4 4 0 Protein of unknwon function (DUF3008) Pollen_allerg_1 PF01357.16 EIW79805.1 - 2.5 7.9 9.9 36 4.2 0.0 5.0 3 3 2 5 5 5 0 Pollen allergen Methyltransf_2 PF00891.13 EIW79807.1 - 1.3e-25 90.0 0.0 1.9e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EIW79807.1 - 0.037 14.6 0.0 0.073 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Arch_ATPase PF01637.13 EIW79808.1 - 0.023 14.4 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_16 PF13191.1 EIW79808.1 - 0.069 13.1 0.1 0.14 12.0 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain Arch_ATPase PF01637.13 EIW79809.1 - 0.00027 20.7 0.0 0.00037 20.2 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase RNA12 PF10443.4 EIW79809.1 - 0.0036 15.8 0.0 0.0036 15.8 0.0 1.1 1 0 0 1 1 1 1 RNA12 protein AAA_11 PF13086.1 EIW79810.1 - 1.4e-60 204.8 0.0 2.2e-60 204.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EIW79810.1 - 1.7e-55 187.4 0.0 2.6e-55 186.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW79810.1 - 5.7e-13 48.4 1.6 5.1e-12 45.3 0.2 2.9 3 0 0 3 3 3 1 Part of AAA domain Viral_helicase1 PF01443.13 EIW79810.1 - 1.8e-11 44.0 0.1 0.012 15.0 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EIW79810.1 - 8.1e-10 38.5 0.1 4.5e-06 26.3 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EIW79810.1 - 4.6e-05 22.9 0.0 0.00017 21.0 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EIW79810.1 - 0.00017 21.7 0.0 0.034 14.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EIW79810.1 - 0.00018 21.8 0.0 0.0006 20.1 0.0 1.9 2 0 0 2 2 1 1 ABC transporter UvrD_C_2 PF13538.1 EIW79810.1 - 0.00029 20.9 0.1 0.0096 16.0 0.0 2.5 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain DUF2075 PF09848.4 EIW79810.1 - 0.00039 19.5 0.1 0.2 10.5 0.0 2.6 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EIW79810.1 - 0.0012 18.8 0.2 0.0049 16.8 0.1 2.2 2 1 0 2 2 2 1 AAA ATPase domain ResIII PF04851.10 EIW79810.1 - 0.0029 17.4 0.0 0.08 12.7 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA PF00004.24 EIW79810.1 - 0.0061 16.7 0.2 0.1 12.8 0.0 2.7 2 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EIW79810.1 - 0.011 15.0 0.0 0.92 8.7 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein PIF1 PF05970.9 EIW79810.1 - 0.033 13.1 0.0 1.7 7.4 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase UvrD_C PF13361.1 EIW79810.1 - 0.059 12.8 0.1 0.15 11.4 0.1 1.5 1 1 0 1 1 1 0 UvrD-like helicase C-terminal domain NACHT PF05729.7 EIW79810.1 - 0.081 12.5 0.0 0.35 10.4 0.0 2.0 2 0 0 2 2 2 0 NACHT domain RNA_helicase PF00910.17 EIW79810.1 - 0.17 12.0 0.1 0.47 10.6 0.0 1.8 2 0 0 2 2 1 0 RNA helicase UvrD-helicase PF00580.16 EIW79810.1 - 0.24 10.6 0.3 1.2 8.3 0.1 2.2 1 1 1 2 2 2 0 UvrD/REP helicase N-terminal domain adh_short_C2 PF13561.1 EIW79811.1 - 1.3e-34 120.0 0.2 1.8e-34 119.5 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIW79811.1 - 1.6e-33 115.9 0.3 2.5e-33 115.3 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW79811.1 - 2.3e-18 66.4 0.1 3.7e-18 65.8 0.1 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW79811.1 - 3.1e-06 26.7 0.1 3.9e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EIW79811.1 - 0.01 14.7 0.3 0.021 13.7 0.1 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EIW79811.1 - 0.015 15.3 0.2 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 NADH(P)-binding 3HCDH_N PF02737.13 EIW79811.1 - 0.016 14.8 0.1 0.091 12.4 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.8 EIW79811.1 - 0.044 13.0 0.3 0.066 12.4 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family Piwi PF02171.12 EIW79812.1 - 1.2e-77 260.9 0.0 1.5e-77 260.5 0.0 1.1 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EIW79812.1 - 4.5e-17 61.6 0.0 7.4e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EIW79812.1 - 2.4e-13 49.2 0.0 5.7e-13 48.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) Nucleoplasmin PF03066.10 EIW79815.1 - 0.75 9.3 7.6 1.6 8.2 5.3 1.5 1 0 0 1 1 1 0 Nucleoplasmin DUF4611 PF15387.1 EIW79815.1 - 2.2 8.4 10.5 10 6.3 7.3 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Cauli_VI PF01693.11 EIW79817.1 - 1.2e-07 31.6 0.5 1.8e-07 31.0 0.4 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin SLA_LP_auto_ag PF05889.8 EIW79818.1 - 0.066 11.6 0.0 0.12 10.8 0.0 1.3 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) UBN2_2 PF14227.1 EIW79819.1 - 3.5e-06 26.5 0.0 6.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EIW79819.1 - 0.00065 19.2 0.0 0.0013 18.3 0.0 1.4 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIW79819.1 - 0.00082 19.1 0.3 0.0018 18.0 0.0 1.7 2 0 0 2 2 2 1 gag-polypeptide of LTR copia-type TPT PF03151.11 EIW79820.1 - 3.8e-21 75.3 10.5 1.8e-20 73.1 0.2 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EIW79820.1 - 7.1e-07 28.4 13.4 8.2e-06 24.9 9.2 2.2 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EIW79820.1 - 4.2e-05 23.5 26.4 8.8e-05 22.5 7.5 2.8 3 1 0 3 3 3 2 EamA-like transporter family zf-C3HC4_2 PF13923.1 EIW79821.1 - 8.4e-08 32.1 2.5 8.4e-08 32.1 1.7 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW79821.1 - 1.2e-06 28.0 0.6 1.2e-06 28.0 0.4 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIW79821.1 - 0.0002 21.1 5.3 0.0002 21.1 3.6 2.5 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EIW79821.1 - 0.0002 20.9 12.5 0.0022 17.6 0.6 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW79821.1 - 0.00059 19.5 1.1 0.00059 19.5 0.8 2.8 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 EIW79821.1 - 0.00064 19.4 9.6 0.00064 19.4 6.7 2.6 2 1 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 EIW79821.1 - 0.005 16.5 0.9 0.0096 15.6 0.6 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 EIW79821.1 - 0.047 13.4 0.3 0.047 13.4 0.2 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-FCS PF06467.9 EIW79821.1 - 0.22 11.1 1.5 13 5.5 0.0 2.6 3 0 0 3 3 3 0 MYM-type Zinc finger with FCS sequence motif ApbA PF02558.11 EIW79822.1 - 5.9e-22 77.7 0.0 9e-22 77.1 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EIW79822.1 - 2.2e-17 63.1 0.0 2.8e-13 49.9 0.0 2.5 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA C terminal NAD_binding_7 PF13241.1 EIW79822.1 - 0.0094 16.1 0.0 0.018 15.2 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding IlvN PF07991.7 EIW79822.1 - 0.044 13.1 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain HMG_box PF00505.14 EIW79824.1 - 0.00034 20.8 0.1 0.00089 19.4 0.1 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIW79824.1 - 0.0071 16.6 0.2 0.014 15.7 0.1 1.5 1 0 0 1 1 1 1 HMG-box domain Piwi PF02171.12 EIW79825.1 - 1.2e-85 287.1 0.0 1.7e-85 286.6 0.0 1.2 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.17 EIW79825.1 - 6.3e-22 77.3 0.0 1.3e-21 76.2 0.0 1.5 1 0 0 1 1 1 1 PAZ domain DUF1785 PF08699.5 EIW79825.1 - 4.1e-18 64.4 0.2 8.9e-18 63.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) YfcL PF08891.6 EIW79826.1 - 0.011 15.6 0.1 0.063 13.2 0.0 2.4 2 0 0 2 2 2 0 YfcL protein V_ATPase_I PF01496.14 EIW79826.1 - 0.012 13.4 0.1 0.051 11.4 0.0 2.0 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF2465 PF10239.4 EIW79826.1 - 0.028 13.6 1.0 0.83 8.8 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2465) Flagellin_N PF00669.15 EIW79826.1 - 0.055 13.2 9.2 5.1 6.8 0.0 3.8 2 1 2 4 4 4 0 Bacterial flagellin N-terminal helical region NPV_P10 PF05531.7 EIW79826.1 - 0.88 9.8 25.6 3.8 7.8 0.3 5.9 2 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF4131 PF13567.1 EIW79828.1 - 8.3 5.7 9.2 1.6 8.1 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) LRR_4 PF12799.2 EIW79829.1 - 0.0072 15.9 0.1 12 5.6 0.0 3.5 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) UCH PF00443.24 EIW79830.1 - 9.8e-09 34.7 0.0 3.3e-08 32.9 0.0 1.7 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EIW79830.1 - 0.004 16.9 0.2 0.0097 15.7 0.2 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 EIW79830.1 - 0.011 15.2 0.0 0.025 14.0 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain CUE PF02845.11 EIW79830.1 - 0.18 11.3 0.0 0.52 9.8 0.0 1.8 1 0 0 1 1 1 0 CUE domain UIM PF02809.15 EIW79830.1 - 0.47 10.1 4.7 18 5.2 0.1 3.1 2 0 0 2 2 2 0 Ubiquitin interaction motif RAP1 PF07218.6 EIW79830.1 - 0.64 8.0 0.1 1.5 6.8 0.1 1.5 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PAPS_reduct PF01507.14 EIW79831.1 - 7.1e-27 94.3 0.0 1.2e-18 67.4 0.0 2.2 2 0 0 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Epimerase PF01370.16 EIW79832.1 - 3.1e-46 157.7 0.0 3.9e-46 157.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIW79832.1 - 9.1e-07 28.0 0.0 3.2e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EIW79832.1 - 2.1e-05 23.5 1.4 0.00042 19.2 1.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EIW79832.1 - 3.8e-05 22.5 0.0 7.3e-05 21.5 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EIW79832.1 - 0.36 10.7 1.7 19 5.1 1.4 2.7 2 1 0 2 2 2 0 short chain dehydrogenase Copper-fist PF00649.13 EIW79833.1 - 6.2e-22 76.5 0.7 6.2e-22 76.5 0.5 2.7 1 1 1 2 2 2 2 Copper fist DNA binding domain DNA_pol_A_exo1 PF01612.15 EIW79834.1 - 4.4e-16 58.8 0.0 6.3e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease HTH_40 PF14493.1 EIW79834.1 - 0.023 14.9 0.0 0.11 12.6 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain FAP PF07174.6 EIW79834.1 - 0.27 10.5 6.8 0.44 9.8 4.7 1.2 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) DnaJ PF00226.26 EIW79835.1 - 1.5e-18 66.2 0.5 5.8e-18 64.3 0.3 2.1 1 0 0 1 1 1 1 DnaJ domain DUF2714 PF10896.3 EIW79835.1 - 5.7e-05 22.9 0.0 9.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2714) PilO PF04350.8 EIW79835.1 - 0.014 15.2 0.0 0.014 15.2 0.0 2.5 2 0 0 2 2 2 0 Pilus assembly protein, PilO Pkinase PF00069.20 EIW79836.1 - 1.1e-50 172.2 0.0 1.6e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW79836.1 - 2.3e-25 89.1 0.0 3.4e-24 85.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW79836.1 - 1.3e-05 24.2 0.0 0.00011 21.3 0.0 2.0 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EIW79836.1 - 0.00037 20.2 0.1 0.0045 16.7 0.0 2.6 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EIW79836.1 - 0.0034 16.4 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.2 EIW79837.1 - 0.021 14.5 0.0 0.066 12.9 0.0 1.9 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.2 EIW79837.1 - 6.9 6.4 15.5 5.7 6.6 0.1 6.3 6 2 1 8 8 8 0 Leucine Rich repeats (2 copies) DNA_pol_A_exo1 PF01612.15 EIW79838.1 - 4.2e-15 55.6 0.0 1.7e-13 50.4 0.0 2.2 1 1 0 1 1 1 1 3'-5' exonuclease Aldo_ket_red PF00248.16 EIW79839.1 - 8e-33 113.4 0.0 1.1e-32 112.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family 4HBT PF03061.17 EIW79840.1 - 6e-07 29.5 0.1 1e-06 28.7 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily FGGY_N PF00370.16 EIW79840.1 - 0.018 14.3 0.0 0.061 12.6 0.0 1.8 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain Proteasome PF00227.21 EIW79842.1 - 9.7e-39 132.6 0.0 1.2e-38 132.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit F-box-like PF12937.2 EIW79843.1 - 0.0061 16.2 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EIW79843.1 - 0.097 12.4 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 F-box-like domain Mre11_DNA_bind PF04152.9 EIW79844.1 - 1.1e-46 158.9 0.1 6.2e-46 156.4 0.0 2.0 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EIW79844.1 - 1.8e-25 89.4 1.0 2.8e-25 88.8 0.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIW79844.1 - 1e-06 28.6 0.0 5e-06 26.4 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PBP1_TM PF14812.1 EIW79844.1 - 0.93 9.8 9.8 0.21 11.9 0.2 2.8 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TPT PF03151.11 EIW79845.1 - 1.3e-08 34.6 13.0 1.3e-08 34.6 9.0 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EIW79845.1 - 0.058 13.4 38.9 0.021 14.8 11.5 3.2 2 1 0 2 2 2 0 EamA-like transporter family F-box-like PF12937.2 EIW79846.1 - 0.063 13.0 0.0 0.28 10.9 0.0 2.2 2 0 0 2 2 2 0 F-box-like LRR_8 PF13855.1 EIW79846.1 - 3.2 7.5 7.0 0.44 10.3 0.1 3.1 4 1 0 4 4 4 0 Leucine rich repeat F-box-like PF12937.2 EIW79847.1 - 0.00042 19.9 0.0 0.001 18.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like Retrotrans_gag PF03732.12 EIW79847.1 - 0.014 15.4 0.6 0.027 14.5 0.4 1.5 1 0 0 1 1 1 0 Retrotransposon gag protein zf-CCHC PF00098.18 EIW79847.1 - 2.1 8.4 5.6 9.7 6.3 3.9 2.1 1 1 0 1 1 1 0 Zinc knuckle Aldo_ket_red PF00248.16 EIW79849.1 - 1.2e-38 132.5 0.0 1.7e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family F-box PF00646.28 EIW79850.1 - 8.5e-06 25.2 0.0 2.3e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW79850.1 - 1.2e-05 24.9 0.1 2.5e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIW79851.1 - 8.9e-06 25.3 0.2 0.016 14.9 0.0 2.8 2 0 0 2 2 2 2 F-box-like STAS_2 PF13466.1 EIW79851.1 - 0.023 14.7 0.0 0.12 12.4 0.0 2.3 1 0 0 1 1 1 0 STAS domain TetR_C_7 PF14246.1 EIW79851.1 - 0.095 12.9 3.1 7.5 6.8 0.1 2.7 2 0 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal region LRR_8 PF13855.1 EIW79852.1 - 0.062 13.0 3.4 1.3 8.8 0.1 3.7 5 0 0 5 5 5 0 Leucine rich repeat D-ser_dehydrat PF14031.1 EIW79853.1 - 2e-17 63.1 0.0 3.8e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EIW79853.1 - 9.2e-11 41.7 0.0 1.5e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Epimerase PF01370.16 EIW79854.1 - 3.9e-67 226.1 0.1 5.2e-67 225.7 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIW79854.1 - 9.8e-07 27.9 0.0 1.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EIW79854.1 - 0.007 15.3 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EIW79854.1 - 0.019 14.2 0.0 0.041 13.1 0.0 1.7 1 1 0 1 1 1 0 NmrA-like family NAD_binding_10 PF13460.1 EIW79854.1 - 0.094 12.7 0.0 0.18 11.8 0.0 1.7 1 1 0 1 1 1 0 NADH(P)-binding HTH_8 PF02954.14 EIW79854.1 - 0.099 12.2 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family adh_short PF00106.20 EIW79854.1 - 0.11 12.4 0.0 0.28 11.0 0.0 1.6 1 1 1 2 2 2 0 short chain dehydrogenase INCA1 PF15142.1 EIW79855.1 - 0.077 12.7 0.3 0.11 12.2 0.2 1.2 1 0 0 1 1 1 0 INCA1 DUF4345 PF14248.1 EIW79856.1 - 0.058 12.8 0.6 0.085 12.3 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4345) 4HBT PF03061.17 EIW79857.1 - 2.5e-10 40.3 0.2 3.3e-10 39.9 0.2 1.2 1 0 0 1 1 1 1 Thioesterase superfamily CHAP PF05257.11 EIW79857.1 - 0.023 14.3 0.0 0.025 14.2 0.0 1.1 1 0 0 1 1 1 0 CHAP domain 4HBT_3 PF13622.1 EIW79857.1 - 0.024 14.3 0.2 0.046 13.4 0.2 1.3 2 0 0 2 2 2 0 Thioesterase-like superfamily Alg6_Alg8 PF03155.10 EIW79858.1 - 1.7e-09 37.0 0.0 2e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family UcrQ PF02939.11 EIW79859.1 - 1.8e-21 75.7 0.8 2.2e-21 75.4 0.6 1.1 1 0 0 1 1 1 1 UcrQ family Ost4 PF10215.4 EIW79860.1 - 2e-11 43.1 3.2 2e-11 43.1 2.2 1.9 3 0 0 3 3 3 1 Oligosaccaryltransferase Pro_CA PF00484.14 EIW79862.1 - 8.8e-12 45.2 0.2 1.6e-11 44.4 0.0 1.5 2 0 0 2 2 2 1 Carbonic anhydrase Aminotran_1_2 PF00155.16 EIW79865.1 - 2.5e-39 135.2 0.0 3.7e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIW79865.1 - 0.00051 19.2 0.0 0.00078 18.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase WD40 PF00400.27 EIW79866.1 - 1.3e-31 107.2 2.7 2e-08 33.8 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EIW79866.1 - 0.17 10.5 0.0 1.2 7.8 0.0 2.0 1 1 0 1 1 1 0 Nup133 N terminal like LRR_6 PF13516.1 EIW79867.1 - 5.2e-06 25.9 0.9 2.1 8.6 0.0 5.9 5 0 0 5 5 5 1 Leucine Rich repeat LRR_7 PF13504.1 EIW79867.1 - 0.29 11.5 3.7 58 4.5 0.1 4.8 5 0 0 5 5 5 0 Leucine rich repeat LRR_8 PF13855.1 EIW79867.1 - 2 8.2 11.5 5.3 6.8 0.0 4.7 4 1 1 5 5 5 0 Leucine rich repeat zf-B_box PF00643.19 EIW79870.1 - 0.28 11.0 10.3 0.031 14.1 3.9 2.0 2 0 0 2 2 2 0 B-box zinc finger Cauli_VI PF01693.11 EIW79871.1 - 6.5e-05 22.8 0.0 0.00012 21.9 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin Ytp1 PF10355.4 EIW79874.1 - 9e-46 156.2 11.6 7.1e-43 146.7 2.1 2.7 1 1 1 2 2 2 2 Protein of unknown function (Ytp1) zf-DHHC PF01529.15 EIW79874.1 - 0.0018 17.6 0.5 0.026 13.9 0.3 2.1 1 1 0 1 1 1 1 DHHC palmitoyltransferase DUF2976 PF11190.3 EIW79874.1 - 0.11 11.9 3.3 1.2 8.7 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Ni_hydr_CYTB PF01292.15 EIW79874.1 - 1.2 8.5 11.4 0.78 9.1 3.1 2.4 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 FAD_binding_3 PF01494.14 EIW79875.1 - 9.3e-82 274.9 0.0 1.2e-81 274.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIW79875.1 - 1.2e-05 25.2 0.0 3e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIW79875.1 - 2.7e-05 23.3 0.0 5e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EIW79875.1 - 0.0001 21.3 0.0 0.00026 20.0 0.0 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase Phe_hydrox_dim PF07976.7 EIW79875.1 - 0.00017 21.2 0.0 0.00035 20.2 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.9 EIW79875.1 - 0.00031 20.7 0.1 0.00093 19.1 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW79875.1 - 0.0035 15.8 0.0 0.0051 15.3 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EIW79875.1 - 0.0049 15.7 0.0 0.0082 15.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EIW79875.1 - 0.0064 16.8 0.0 0.018 15.3 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIW79875.1 - 0.0071 15.3 0.2 0.012 14.5 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EIW79875.1 - 0.013 15.5 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIW79875.1 - 0.016 13.8 0.1 0.022 13.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.9 EIW79875.1 - 0.019 14.3 0.0 0.037 13.4 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 EIW79875.1 - 0.019 14.7 0.1 0.043 13.6 0.1 1.6 1 0 0 1 1 1 0 ThiF family NAD_binding_7 PF13241.1 EIW79875.1 - 0.034 14.4 0.1 0.2 11.9 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EIW79875.1 - 0.045 13.5 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 EIW79875.1 - 0.048 12.7 0.0 0.12 11.3 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase 3HCDH_N PF02737.13 EIW79875.1 - 0.05 13.2 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EIW79875.1 - 0.1 12.0 0.1 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Fibrinogen_aC PF12160.3 EIW79875.1 - 0.18 11.2 0.1 3.3 7.2 0.0 2.3 2 0 0 2 2 2 0 Fibrinogen alpha C domain Fungal_trans PF04082.13 EIW79876.1 - 9.7e-07 27.9 0.0 1.5e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW79876.1 - 6.3e-05 22.8 9.6 0.0001 22.1 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TPR_12 PF13424.1 EIW79876.1 - 0.023 14.6 0.2 0.1 12.5 0.0 1.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Fungal_trans_2 PF11951.3 EIW79876.1 - 0.025 13.1 0.0 0.034 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Abhydrolase_3 PF07859.8 EIW79878.1 - 1.3e-21 77.1 0.0 3.7e-21 75.6 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold AMP-binding PF00501.23 EIW79880.1 - 9.7e-31 106.5 0.0 2e-30 105.5 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EIW79880.1 - 2e-27 95.7 0.0 6.5e-27 94.0 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein PP-binding PF00550.20 EIW79880.1 - 1.8e-10 40.8 0.1 4.1e-10 39.7 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EIW79880.1 - 0.0022 17.4 0.1 0.011 15.1 0.0 2.2 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIW79880.1 - 0.012 14.2 0.0 0.1 11.2 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DEK_C PF08766.6 EIW79880.1 - 0.2 11.4 0.4 0.71 9.6 0.0 2.0 2 0 0 2 2 2 0 DEK C terminal domain DUF1215 PF06744.7 EIW79881.1 - 0.038 13.6 0.0 0.42 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1215) Aldedh PF00171.17 EIW79883.1 - 4.9e-175 582.3 3.0 5.5e-175 582.1 2.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIW79883.1 - 0.015 14.0 0.0 0.042 12.5 0.0 1.6 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EIW79883.1 - 0.018 14.2 0.0 5.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) MIF PF01187.13 EIW79884.1 - 1.2e-09 38.2 0.0 1.4e-09 38.0 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Aldo_ket_red PF00248.16 EIW79887.1 - 1.8e-76 256.6 0.0 2.1e-76 256.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family F-box-like PF12937.2 EIW79889.1 - 0.039 13.6 0.1 0.19 11.4 0.0 2.2 2 0 0 2 2 2 0 F-box-like Oxidored_FMN PF00724.15 EIW79890.1 - 4.8e-100 334.8 0.0 5.5e-100 334.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Aldedh PF00171.17 EIW79891.1 - 2.1e-175 583.5 2.6 2.4e-175 583.3 1.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIW79891.1 - 0.015 14.0 0.0 0.042 12.5 0.0 1.6 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EIW79891.1 - 0.018 14.2 0.0 5.1 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Abhydrolase_6 PF12697.2 EIW79893.1 - 3.1e-20 73.0 1.9 5e-20 72.3 1.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW79893.1 - 1.2e-06 28.3 0.0 3.3e-06 26.8 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW79893.1 - 4.3e-05 23.2 0.0 0.00011 22.0 0.0 1.7 2 1 0 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EIW79893.1 - 0.0021 17.7 0.0 0.0034 17.0 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Peptidase_S9 PF00326.16 EIW79893.1 - 0.0073 15.5 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family PAF-AH_p_II PF03403.8 EIW79893.1 - 0.031 12.5 0.0 0.047 11.9 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.2 EIW79893.1 - 0.062 12.1 0.0 0.12 11.2 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 EIW79893.1 - 0.13 11.0 0.0 0.22 10.2 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase SET PF00856.23 EIW79895.1 - 8.2e-27 94.4 0.1 1.8e-26 93.3 0.1 1.6 1 1 0 1 1 1 1 SET domain DUF4185 PF13810.1 EIW79896.1 - 0.0025 16.7 0.0 0.0049 15.8 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4185) COesterase PF00135.23 EIW79897.1 - 7e-18 64.6 0.0 2.6e-17 62.7 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family SNF5 PF04855.7 EIW79898.1 - 5.7e-15 55.4 0.1 6.1e-15 55.3 0.0 1.0 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GCC2_GCC3 PF07699.8 EIW79899.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 GCC2 and GCC3 HMG_box PF00505.14 EIW79900.1 - 0.022 15.0 0.6 0.046 13.9 0.4 1.5 1 0 0 1 1 1 0 HMG (high mobility group) box HMG_box_2 PF09011.5 EIW79900.1 - 0.052 13.9 0.7 0.18 12.1 0.5 2.0 1 1 0 1 1 1 0 HMG-box domain AT_hook PF02178.14 EIW79900.1 - 0.065 12.9 1.9 0.23 11.2 1.3 1.9 1 0 0 1 1 1 0 AT hook motif PBP1_TM PF14812.1 EIW79901.1 - 0.04 14.2 14.0 0.53 10.6 6.6 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CT47 PF15623.1 EIW79901.1 - 0.094 12.4 10.9 0.11 12.2 7.6 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 Nucleo_P87 PF07267.6 EIW79901.1 - 0.6 8.7 6.2 0.7 8.4 4.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 VID27 PF08553.5 EIW79901.1 - 2.3 6.3 7.3 3.2 5.8 5.0 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein PGA2 PF07543.7 EIW79901.1 - 3.9 7.2 12.0 2.7 7.7 5.8 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF3408 PF11888.3 EIW79901.1 - 5.7 6.8 9.8 5.7 6.8 2.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Transposase_21 PF02992.9 EIW79902.1 - 2.1e-10 40.1 0.2 6.1e-10 38.5 0.0 1.8 2 0 0 2 2 2 1 Transposase family tnp2 SDA1 PF05285.7 EIW79902.1 - 3.1 7.0 15.5 4.8 6.3 10.7 1.2 1 0 0 1 1 1 0 SDA1 Acetyltransf_1 PF00583.19 EIW79903.1 - 3.1e-09 36.7 0.0 4e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EIW79903.1 - 1.6e-07 31.4 0.0 2.1e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIW79903.1 - 9.2e-07 28.9 0.0 1.2e-06 28.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIW79903.1 - 0.00033 20.5 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EIW79903.1 - 0.0089 15.8 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 EIW79903.1 - 0.037 13.9 0.0 0.054 13.3 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.2 EIW79904.1 - 4.5e-19 69.2 2.1 8.7e-19 68.2 1.5 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW79904.1 - 1.7e-06 27.8 0.0 5.3e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW79904.1 - 5.3e-05 23.0 0.0 0.00013 21.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIW79904.1 - 0.0014 17.8 0.0 0.0024 17.1 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Ser_hydrolase PF06821.8 EIW79904.1 - 0.0021 17.6 0.0 0.0039 16.8 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase Lipase_3 PF01764.20 EIW79904.1 - 0.0067 16.0 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) PAF-AH_p_II PF03403.8 EIW79904.1 - 0.03 12.6 0.0 0.046 12.0 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.2 EIW79904.1 - 0.07 11.9 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.6 EIW79904.1 - 0.19 10.4 0.0 0.32 9.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase FHA PF00498.21 EIW79905.1 - 0.071 13.2 0.0 0.38 10.8 0.0 2.1 1 1 0 1 1 1 0 FHA domain GMC_oxred_N PF00732.14 EIW79906.1 - 1.2e-59 201.8 0.0 1.6e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIW79906.1 - 8.4e-33 113.6 0.0 1.4e-32 112.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIW79906.1 - 1.7e-07 30.4 0.1 1.9e-05 23.7 0.0 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW79906.1 - 2e-05 24.4 0.4 9.2e-05 22.3 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIW79906.1 - 0.00013 21.0 0.0 0.00018 20.5 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EIW79906.1 - 0.00048 19.3 0.1 0.0009 18.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EIW79906.1 - 0.0047 15.8 0.7 0.0069 15.2 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EIW79906.1 - 0.015 15.6 0.3 0.29 11.5 0.1 2.9 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW79906.1 - 0.015 13.7 0.0 0.028 12.9 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 EIW79906.1 - 0.024 14.5 0.0 0.09 12.6 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW79906.1 - 0.034 13.0 0.0 0.05 12.5 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 EIW79906.1 - 0.062 12.3 0.0 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 EIW79906.1 - 0.15 11.8 0.7 0.4 10.4 0.0 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding adh_short PF00106.20 EIW79908.1 - 0.015 15.2 0.4 1.6 8.6 0.0 2.9 2 1 0 2 2 2 0 short chain dehydrogenase HMGL-like PF00682.14 EIW79909.1 - 1.3e-53 182.0 0.0 1.8e-53 181.6 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EIW79909.1 - 0.0012 18.5 0.1 0.0023 17.7 0.1 1.4 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain GMC_oxred_N PF00732.14 EIW79910.1 - 6e-55 186.4 0.0 8.1e-55 186.0 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIW79910.1 - 1.1e-31 110.0 0.0 1.9e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EIW79910.1 - 2.5e-06 26.5 0.9 0.00084 18.2 0.6 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EIW79910.1 - 4.9e-06 25.6 0.2 8.2e-05 21.6 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIW79910.1 - 2.8e-05 23.2 0.0 4.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EIW79910.1 - 9.1e-05 22.4 0.1 0.0003 20.7 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EIW79910.1 - 0.0011 17.5 0.0 0.004 15.6 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EIW79910.1 - 0.0066 16.3 0.0 0.021 14.7 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW79910.1 - 0.013 15.5 0.1 0.098 12.7 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW79910.1 - 0.022 13.8 0.1 0.037 13.1 0.1 1.2 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.1 EIW79910.1 - 0.081 11.8 0.0 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Aconitase PF00330.15 EIW79911.1 - 3.1e-176 586.4 0.0 3.7e-176 586.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EIW79911.1 - 6.5e-35 120.0 0.0 1.2e-34 119.2 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain F-box-like PF12937.2 EIW79912.1 - 0.0045 16.6 0.0 0.012 15.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like MRG PF05712.8 EIW79912.1 - 0.18 10.7 0.0 0.27 10.1 0.0 1.4 1 0 0 1 1 1 0 MRG F-box-like PF12937.2 EIW79913.1 - 0.035 13.8 0.0 0.092 12.4 0.0 1.8 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.2 EIW79913.1 - 0.34 10.5 4.6 19 5.0 0.2 4.6 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_4 PF12799.2 EIW79914.1 - 0.21 11.2 6.2 16 5.2 0.1 4.2 3 2 0 3 3 3 0 Leucine Rich repeats (2 copies) DJ-1_PfpI PF01965.19 EIW79915.1 - 2.2e-22 79.1 0.0 3.4e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EIW79915.1 - 5.5e-10 38.5 0.1 1e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family ADH_N PF08240.7 EIW79916.1 - 2.5e-23 81.9 2.1 2.5e-23 81.9 1.5 2.7 3 1 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW79916.1 - 7.3e-19 67.6 0.6 1.1e-18 67.0 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW79916.1 - 0.0028 18.5 0.0 0.0055 17.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AMP-binding PF00501.23 EIW79917.1 - 3.3e-30 104.8 0.2 1.1e-29 103.0 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EIW79917.1 - 4.4e-27 94.6 0.0 9e-27 93.5 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.20 EIW79917.1 - 6.1e-10 39.2 0.1 1.4e-09 38.0 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Epimerase PF01370.16 EIW79917.1 - 0.00055 19.4 0.2 0.01 15.2 0.0 2.6 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family Abhydrolase_3 PF07859.8 EIW79919.1 - 2.9e-34 118.5 0.0 4.3e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EIW79919.1 - 0.0066 15.2 0.0 0.034 12.8 0.0 1.8 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EIW79919.1 - 0.074 12.8 0.0 0.22 11.2 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family adh_short PF00106.20 EIW79920.1 - 1.9e-24 86.4 0.1 2.4e-24 86.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EIW79920.1 - 1.6e-08 34.7 0.0 2.6e-08 34.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EIW79920.1 - 1.7e-08 34.5 0.0 2.3e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW79920.1 - 7e-07 29.0 0.0 1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EIW79920.1 - 0.00016 20.7 0.0 0.00021 20.2 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EIW79920.1 - 0.0011 18.4 0.1 0.0016 17.8 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EIW79920.1 - 0.0095 15.1 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.21 EIW79920.1 - 0.031 13.8 0.2 0.086 12.3 0.1 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.12 EIW79920.1 - 0.037 12.9 0.1 0.054 12.3 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain BTB PF00651.26 EIW79922.1 - 9e-08 32.0 0.0 1.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Pkinase PF00069.20 EIW79923.1 - 2.2e-17 63.0 0.0 3.6e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EIW79923.1 - 1.1e-14 53.6 15.3 5.7e-09 35.5 0.8 6.2 7 0 0 7 7 7 3 WD domain, G-beta repeat HEAT PF02985.17 EIW79923.1 - 1.1e-08 34.4 10.9 0.021 14.8 0.2 5.0 4 0 0 4 4 4 3 HEAT repeat Pkinase_Tyr PF07714.12 EIW79923.1 - 7.1e-05 21.9 0.0 0.031 13.3 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase HEAT_2 PF13646.1 EIW79923.1 - 0.00053 20.2 5.7 0.041 14.1 0.4 2.9 1 1 2 3 3 3 3 HEAT repeats Cohesin_HEAT PF12765.2 EIW79923.1 - 9.7 6.2 10.3 3.7 7.6 0.1 4.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion tRNA-synt_2b PF00587.20 EIW79924.1 - 6.1e-46 156.1 0.1 1e-45 155.4 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EIW79924.1 - 3.1e-18 65.4 0.4 7.6e-18 64.2 0.3 1.7 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 EIW79924.1 - 7e-14 51.4 0.0 1.8e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 EIW79924.1 - 1.2e-12 47.5 0.0 2.2e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain CSTF2_hinge PF14327.1 EIW79925.1 - 1.2e-12 47.6 1.3 1.2e-12 47.6 0.9 2.3 2 0 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.1 EIW79925.1 - 3.4e-08 32.6 2.5 7.8e-08 31.4 1.7 1.6 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal DUF605 PF04652.11 EIW79925.1 - 5.8 6.1 25.7 8 5.7 17.8 1.1 1 0 0 1 1 1 0 Vta1 like CSTF2_hinge PF14327.1 EIW79926.1 - 5.1e-05 23.2 0.1 8.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_5 PF13893.1 EIW79926.1 - 0.0041 16.9 0.0 0.0063 16.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSP20 PF00011.16 EIW79927.1 - 6.2e-13 48.4 0.0 1e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Tektin PF03148.9 EIW79927.1 - 0.0042 15.6 0.7 0.0056 15.2 0.5 1.1 1 0 0 1 1 1 1 Tektin family Fungal_trans PF04082.13 EIW79928.1 - 3.4e-11 42.5 0.0 6.6e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW79928.1 - 1.4e-05 24.8 12.9 3.3e-05 23.6 9.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TBCC PF07986.7 EIW79930.1 - 2e-28 98.1 0.7 3.5e-28 97.4 0.5 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C Laminin_II PF06009.7 EIW79930.1 - 0.12 12.1 0.2 0.38 10.4 0.2 1.9 1 0 0 1 1 1 0 Laminin Domain II WD40 PF00400.27 EIW79931.1 - 1e-13 50.5 6.7 5.9e-07 29.1 0.0 6.0 8 0 0 8 8 8 3 WD domain, G-beta repeat PD40 PF07676.7 EIW79931.1 - 6.9e-08 31.9 1.1 0.43 10.3 0.0 5.5 5 0 0 5 5 5 3 WD40-like Beta Propeller Repeat Peptidase_S9 PF00326.16 EIW79932.1 - 4e-24 85.0 0.0 4.3e-24 84.9 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EIW79932.1 - 3.5e-07 30.3 0.0 1.3e-06 28.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW79932.1 - 4.4e-06 26.5 0.0 6.3e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EIW79932.1 - 0.00013 21.4 0.0 0.0094 15.4 0.0 2.0 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EIW79932.1 - 0.00085 18.9 0.0 0.0012 18.4 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EIW79932.1 - 0.013 15.1 0.0 1.8 8.0 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.13 EIW79932.1 - 0.022 14.0 0.0 0.45 9.7 0.0 2.0 1 1 0 1 1 1 0 Dienelactone hydrolase family Peptidase_S15 PF02129.13 EIW79932.1 - 0.059 12.7 0.0 4.9 6.4 0.0 2.1 1 1 1 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) PAF-AH_p_II PF03403.8 EIW79932.1 - 0.098 10.9 0.0 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II M20_dimer PF07687.9 EIW79933.1 - 1.1e-06 28.4 0.1 5e-06 26.2 0.1 2.1 1 1 0 1 1 1 1 Peptidase dimerisation domain COesterase PF00135.23 EIW79934.1 - 1.1e-91 308.2 0.7 1.1e-90 304.8 0.5 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW79934.1 - 1.4e-07 31.3 0.0 1.1e-06 28.4 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold MFS_1 PF07690.11 EIW79936.1 - 4.3e-17 61.8 43.5 3.2e-10 39.2 13.4 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Cytomega_TRL10 PF06084.6 EIW79936.1 - 0.24 11.1 0.2 0.54 10.0 0.1 1.5 1 0 0 1 1 1 0 Cytomegalovirus TRL10 protein DUF1625 PF07787.7 EIW79936.1 - 0.27 10.4 4.3 0.69 9.1 3.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) BTB PF00651.26 EIW79937.1 - 3.7e-09 36.5 0.0 6.8e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Chaperone_III PF07824.7 EIW79937.1 - 0.0064 16.4 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 Type III secretion chaperone domain BTB PF00651.26 EIW79938.1 - 3e-08 33.6 0.0 5.8e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Acetyltransf_7 PF13508.1 EIW79939.1 - 0.14 12.3 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain MRG PF05712.8 EIW79941.1 - 0.058 12.2 0.0 0.074 11.9 0.0 1.2 1 0 0 1 1 1 0 MRG DUF2360 PF10152.4 EIW79942.1 - 0.05 13.8 1.8 0.076 13.3 1.3 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) BTB PF00651.26 EIW79946.1 - 3.8e-05 23.6 0.0 8.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain NACHT PF05729.7 EIW79947.1 - 6.2e-11 42.2 0.0 1.1e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW79947.1 - 5.8e-07 29.6 0.3 1.5e-06 28.3 0.1 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EIW79947.1 - 7.8e-07 29.2 0.0 8.9e-06 25.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIW79947.1 - 0.0032 17.6 0.0 0.0066 16.6 0.0 1.5 1 0 0 1 1 1 1 RNA helicase APS_kinase PF01583.15 EIW79947.1 - 0.0097 15.5 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.1 EIW79947.1 - 0.011 16.0 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EIW79947.1 - 0.023 14.3 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA PF00004.24 EIW79947.1 - 0.037 14.2 0.0 0.063 13.4 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EIW79947.1 - 0.047 13.9 0.0 0.082 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter MobB PF03205.9 EIW79947.1 - 0.048 13.3 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.13 EIW79947.1 - 0.048 13.2 0.0 0.083 12.4 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family FF PF01846.14 EIW79947.1 - 0.054 13.4 0.1 0.34 10.9 0.0 2.4 3 0 0 3 3 2 0 FF domain DUF258 PF03193.11 EIW79947.1 - 0.066 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 EIW79947.1 - 0.071 12.8 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EIW79947.1 - 0.11 12.3 0.1 0.32 10.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 EIW79947.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) UPF0079 PF02367.12 EIW79947.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 EIW79947.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 EIW79949.1 - 8.2e-08 32.0 0.0 1.5e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW79949.1 - 1.9e-07 31.2 0.1 3.2e-07 30.5 0.1 1.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW79949.1 - 0.00078 19.5 0.0 0.00093 19.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EIW79949.1 - 0.0017 18.0 0.0 0.0067 16.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EIW79949.1 - 0.0023 18.0 0.0 0.0033 17.5 0.0 1.5 1 1 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 EIW79949.1 - 0.0083 16.4 0.0 0.011 16.0 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EIW79949.1 - 0.009 16.2 0.0 0.014 15.5 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 EIW79949.1 - 0.01 15.5 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase ABC_tran PF00005.22 EIW79949.1 - 0.014 15.6 0.1 0.015 15.6 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.21 EIW79949.1 - 0.018 14.5 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain PRK PF00485.13 EIW79949.1 - 0.047 13.2 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF815 PF05673.8 EIW79949.1 - 0.071 12.0 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) GCD14 PF08704.5 EIW79949.1 - 0.17 11.3 0.3 0.39 10.1 0.1 1.5 1 1 1 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Chitin_synth_2 PF03142.10 EIW79950.1 - 5.8e-238 790.5 0.1 9.1e-238 789.9 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EIW79950.1 - 1.3e-153 512.6 0.0 1.7e-153 512.2 0.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DEK_C PF08766.6 EIW79950.1 - 4e-18 64.9 0.4 2.1e-17 62.6 0.1 2.2 2 0 0 2 2 2 1 DEK C terminal domain Cyt-b5 PF00173.23 EIW79950.1 - 1.6e-17 63.0 0.0 1.9e-10 40.3 0.0 2.8 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 EIW79950.1 - 4.1e-15 56.2 0.0 4.4e-11 43.0 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EIW79950.1 - 1.6e-10 41.0 3.1 1.6e-10 41.0 2.2 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EIW79950.1 - 0.0068 16.0 0.0 0.79 9.3 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 AAA_29 PF13555.1 EIW79950.1 - 0.054 13.0 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Med3 PF11593.3 EIW79950.1 - 2.1 7.4 7.6 4 6.5 5.3 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal YwiC PF14256.1 EIW79950.1 - 2.9 7.9 12.3 0.039 14.0 0.9 2.4 2 0 0 2 2 2 0 YwiC-like protein BTB PF00651.26 EIW79952.1 - 1.4e-07 31.4 0.0 2.4e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain NACHT PF05729.7 EIW79954.1 - 6.2e-07 29.2 0.0 1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EIW79954.1 - 5.5e-05 23.3 0.0 7.9e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW79954.1 - 0.00015 21.8 0.3 0.00022 21.2 0.2 1.3 1 1 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.4 EIW79954.1 - 0.0014 17.7 0.0 0.0015 17.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EIW79954.1 - 0.0018 18.3 0.0 0.0029 17.7 0.0 1.3 1 0 0 1 1 1 1 RNA helicase APS_kinase PF01583.15 EIW79954.1 - 0.0025 17.4 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase NB-ARC PF00931.17 EIW79954.1 - 0.011 14.5 0.0 0.015 14.1 0.0 1.3 1 1 0 1 1 1 0 NB-ARC domain Arch_ATPase PF01637.13 EIW79954.1 - 0.018 14.7 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase DUF815 PF05673.8 EIW79954.1 - 0.03 13.2 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) PhoH PF02562.11 EIW79954.1 - 0.038 13.2 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein AAA PF00004.24 EIW79954.1 - 0.066 13.4 0.0 0.11 12.6 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TAP42 PF04177.7 EIW79954.1 - 0.081 11.8 0.0 0.096 11.6 0.0 1.1 1 0 0 1 1 1 0 TAP42-like family T2SE PF00437.15 EIW79954.1 - 0.084 11.7 0.0 0.13 11.1 0.0 1.4 1 1 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.21 EIW79954.1 - 0.086 12.3 0.0 0.22 10.9 0.0 1.7 1 1 1 2 2 2 0 Sigma-54 interaction domain ABC_tran PF00005.22 EIW79954.1 - 0.086 13.1 0.1 0.38 11.0 0.0 2.0 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 EIW79954.1 - 0.094 12.4 0.0 0.12 12.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Parvo_NS1 PF01057.12 EIW79954.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 WW PF00397.21 EIW79956.1 - 5e-06 26.2 4.6 1.1e-05 25.2 3.2 1.6 1 0 0 1 1 1 1 WW domain Usp PF00582.21 EIW79957.1 - 3.3e-15 56.5 0.0 4.4e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family PK_C PF02887.11 EIW79957.1 - 0.076 12.5 0.0 2 8.0 0.0 2.3 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain NACHT PF05729.7 EIW79958.1 - 7.1e-12 45.3 0.1 1.4e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW79958.1 - 1.2e-05 25.4 0.8 2.3e-05 24.4 0.5 1.7 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.22 EIW79958.1 - 0.00017 21.8 0.0 0.00056 20.2 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 EIW79958.1 - 0.00027 21.0 0.0 0.00061 19.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EIW79958.1 - 0.00046 19.8 0.1 0.00086 18.9 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase Arch_ATPase PF01637.13 EIW79958.1 - 0.00055 19.7 0.0 0.00084 19.1 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase RNA_helicase PF00910.17 EIW79958.1 - 0.00068 19.7 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 RNA helicase UPF0079 PF02367.12 EIW79958.1 - 0.0025 17.4 0.0 0.0052 16.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 EIW79958.1 - 0.0096 15.3 0.5 0.041 13.2 0.2 2.2 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EIW79958.1 - 0.019 14.4 0.1 0.054 13.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EIW79958.1 - 0.021 14.6 0.2 0.1 12.4 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_31 PF13614.1 EIW79958.1 - 0.028 14.3 0.4 7.7 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EIW79958.1 - 0.029 13.8 0.0 0.061 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain TIP49 PF06068.8 EIW79958.1 - 0.029 13.1 0.0 0.042 12.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Sigma54_activ_2 PF14532.1 EIW79958.1 - 0.042 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain PRK PF00485.13 EIW79958.1 - 0.043 13.3 0.0 0.068 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family CPT PF07931.7 EIW79958.1 - 0.067 12.8 0.0 0.11 12.0 0.0 1.5 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein IstB_IS21 PF01695.12 EIW79958.1 - 0.067 12.5 0.0 0.38 10.1 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 EIW79958.1 - 0.069 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.8 EIW79958.1 - 0.072 12.0 0.1 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA PF00004.24 EIW79958.1 - 0.076 13.2 0.0 0.26 11.4 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EIW79958.1 - 0.08 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_17 PF13207.1 EIW79958.1 - 0.08 13.7 0.0 0.18 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIW79958.1 - 0.11 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_PrkA PF08298.6 EIW79958.1 - 0.12 11.0 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain PIF1 PF05970.9 EIW79958.1 - 0.13 11.1 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase YolD PF08863.5 EIW79961.1 - 0.096 12.5 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 YolD-like protein NACHT PF05729.7 EIW79962.1 - 1.9e-12 47.1 0.0 3.3e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW79962.1 - 2.5e-05 24.3 0.2 0.00012 22.1 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EIW79962.1 - 3.5e-05 23.9 0.0 7.7e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EIW79962.1 - 5.7e-05 22.9 0.0 9.3e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase APS_kinase PF01583.15 EIW79962.1 - 0.00071 19.2 0.1 0.0019 17.8 0.0 1.7 2 0 0 2 2 2 1 Adenylylsulphate kinase RNA_helicase PF00910.17 EIW79962.1 - 0.00086 19.4 0.0 0.0017 18.5 0.0 1.5 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.22 EIW79962.1 - 0.016 15.5 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA PF00004.24 EIW79962.1 - 0.055 13.6 0.0 0.19 11.8 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EIW79962.1 - 0.11 11.8 0.0 0.21 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EIW79962.1 - 0.11 13.2 0.0 0.38 11.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EIW79962.1 - 0.12 11.5 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.1 EIW79962.1 - 0.13 12.1 0.0 0.47 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EIW79962.1 - 0.14 12.2 0.0 0.33 10.9 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.1 EIW79962.1 - 0.15 11.6 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.13 EIW79962.1 - 0.15 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EIW79962.1 - 0.16 12.2 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EIW79963.1 - 3.4e-08 33.3 0.1 7.4e-08 32.2 0.1 1.6 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EIW79963.1 - 0.0011 19.1 0.0 0.0034 17.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW79963.1 - 0.0017 18.4 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EIW79963.1 - 0.014 14.7 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EIW79963.1 - 0.015 15.4 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.15 EIW79963.1 - 0.036 13.7 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase ABC_tran PF00005.22 EIW79963.1 - 0.041 14.1 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 ABC transporter UPF0079 PF02367.12 EIW79963.1 - 0.049 13.2 0.1 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_29 PF13555.1 EIW79963.1 - 0.053 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 EIW79963.1 - 0.073 13.2 0.0 0.2 11.8 0.0 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EIW79963.1 - 0.15 11.1 0.0 0.37 9.8 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin Sigma54_activ_2 PF14532.1 EIW79963.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 EIW79964.1 - 1.3e-10 41.1 0.2 4.2e-10 39.5 0.2 1.8 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW79964.1 - 1.3e-07 31.7 0.1 2.6e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW79964.1 - 3.4e-05 23.9 0.0 8.4e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EIW79964.1 - 0.00097 18.8 0.0 0.002 17.8 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase ABC_tran PF00005.22 EIW79964.1 - 0.0023 18.2 0.0 0.0043 17.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_5 PF07728.9 EIW79964.1 - 0.0046 16.6 0.0 0.009 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EIW79964.1 - 0.0069 15.5 0.1 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.1 EIW79964.1 - 0.0093 15.4 0.1 0.025 14.1 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain MobB PF03205.9 EIW79964.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EIW79964.1 - 0.012 15.7 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase UPF0079 PF02367.12 EIW79964.1 - 0.015 14.9 0.0 0.033 13.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 EIW79964.1 - 0.017 14.5 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EIW79964.1 - 0.019 14.4 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF258 PF03193.11 EIW79964.1 - 0.024 13.8 0.0 0.038 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Sigma54_activat PF00158.21 EIW79964.1 - 0.024 14.1 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 EIW79964.1 - 0.025 13.7 0.0 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_PrkA PF08298.6 EIW79964.1 - 0.027 13.1 0.0 0.043 12.5 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain Sigma54_activ_2 PF14532.1 EIW79964.1 - 0.029 14.4 0.0 0.08 12.9 0.0 1.7 2 0 0 2 2 1 0 Sigma-54 interaction domain APS_kinase PF01583.15 EIW79964.1 - 0.032 13.9 0.0 0.05 13.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_33 PF13671.1 EIW79964.1 - 0.038 13.8 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 EIW79964.1 - 0.056 12.6 0.0 0.091 11.9 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EIW79964.1 - 0.074 13.8 0.0 0.23 12.3 0.0 1.9 2 1 1 3 3 1 0 AAA domain AAA PF00004.24 EIW79964.1 - 0.086 13.0 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EIW79964.1 - 0.14 11.6 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain NB-ARC PF00931.17 EIW79964.1 - 0.14 10.9 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain PRK PF00485.13 EIW79964.1 - 0.17 11.4 0.1 0.26 10.8 0.1 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNase_PH PF01138.16 EIW79965.1 - 5e-28 98.0 0.0 8.3e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EIW79965.1 - 0.081 12.8 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 ABC_membrane PF00664.18 EIW79967.1 - 1.5e-58 198.4 14.2 1.1e-31 110.3 1.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIW79967.1 - 4.7e-57 192.1 0.0 6.2e-30 104.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EIW79967.1 - 1.2e-13 50.7 0.0 3e-05 23.3 0.0 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EIW79967.1 - 9.4e-08 32.9 0.0 0.011 16.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EIW79967.1 - 1.1e-07 32.1 0.0 0.77 9.6 0.0 4.1 3 1 1 4 4 4 2 AAA domain AAA_16 PF13191.1 EIW79967.1 - 1.7e-07 31.3 7.8 6.6e-05 22.9 0.2 3.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EIW79967.1 - 2.9e-07 29.9 0.3 0.011 15.2 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain IstB_IS21 PF01695.12 EIW79967.1 - 8.9e-07 28.4 0.1 0.44 9.9 0.0 4.2 4 0 0 4 4 4 2 IstB-like ATP binding protein DUF258 PF03193.11 EIW79967.1 - 6.4e-06 25.4 0.0 0.072 12.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIW79967.1 - 4.4e-05 23.6 2.7 0.027 14.6 0.1 3.7 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EIW79967.1 - 7.7e-05 23.0 0.0 0.53 10.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EIW79967.1 - 0.00011 21.6 2.5 0.11 11.9 0.0 3.6 3 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EIW79967.1 - 0.00016 21.4 0.0 1.1 9.1 0.0 3.1 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 EIW79967.1 - 0.00025 21.0 2.2 0.48 10.3 0.3 3.7 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EIW79967.1 - 0.00064 19.6 1.6 1.2 8.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_10 PF12846.2 EIW79967.1 - 0.00089 18.7 4.2 1.2 8.5 0.1 3.9 4 0 0 4 4 4 1 AAA-like domain Zeta_toxin PF06414.7 EIW79967.1 - 0.0013 17.9 0.1 1.1 8.2 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_30 PF13604.1 EIW79967.1 - 0.0021 17.6 3.1 0.035 13.6 0.1 3.4 4 1 0 4 4 3 1 AAA domain ABC_ATPase PF09818.4 EIW79967.1 - 0.012 14.2 0.2 0.15 10.6 0.0 2.6 3 0 0 3 3 3 0 Predicted ATPase of the ABC class AAA_5 PF07728.9 EIW79967.1 - 0.021 14.5 0.2 1.2 8.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 EIW79967.1 - 0.053 12.3 0.1 0.96 8.2 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA PF00004.24 EIW79967.1 - 0.066 13.4 0.0 2.4 8.3 0.0 3.3 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 EIW79967.1 - 0.078 12.7 0.5 9 6.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 RNA_helicase PF00910.17 EIW79967.1 - 0.081 13.1 0.1 4.1 7.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase APS_kinase PF01583.15 EIW79967.1 - 0.091 12.4 0.2 5.2 6.6 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase PRK PF00485.13 EIW79967.1 - 0.14 11.6 0.3 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.7 EIW79967.1 - 0.17 11.5 1.0 21 4.7 0.2 2.7 2 0 0 2 2 2 0 NACHT domain KaiC PF06745.8 EIW79967.1 - 0.46 9.5 3.0 15 4.6 0.0 2.8 3 0 0 3 3 2 0 KaiC G-alpha PF00503.15 EIW79967.1 - 0.56 8.8 0.0 2.9 6.4 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit Asp PF00026.18 EIW79969.1 - 5e-48 163.9 18.4 8.8e-48 163.1 12.7 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW79969.1 - 1.3e-08 35.0 5.2 1.4e-06 28.3 1.6 3.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIW79969.1 - 0.038 14.4 8.0 0.3 11.6 0.7 3.2 3 1 0 3 3 3 0 Aspartyl protease WXG100 PF06013.7 EIW79974.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 Proteins of 100 residues with WXG UDPG_MGDP_dh_N PF03721.9 EIW79975.1 - 8.4e-57 191.5 0.0 1.9e-56 190.3 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 EIW79975.1 - 1.4e-31 108.5 0.0 2.5e-31 107.7 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 EIW79975.1 - 1e-30 105.9 0.0 4.6e-29 100.6 0.0 2.3 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_Gly3P_dh_N PF01210.18 EIW79975.1 - 0.011 15.5 0.4 5.4 6.7 0.0 2.8 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF4608 PF15381.1 EIW79975.1 - 0.07 13.2 0.3 0.19 11.9 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4608) F-box-like PF12937.2 EIW79976.1 - 1.8e-07 30.7 1.2 1.8e-07 30.7 0.9 2.8 3 0 0 3 3 3 1 F-box-like F-box-like_2 PF13013.1 EIW79976.1 - 0.0055 16.4 2.9 0.011 15.4 0.6 2.5 2 1 0 2 2 2 1 F-box-like domain NAD_binding_4 PF07993.7 EIW79977.1 - 7.3e-33 113.5 0.0 1.4e-32 112.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EIW79977.1 - 1.2e-26 93.1 0.0 1.4e-25 89.5 0.0 2.2 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EIW79977.1 - 3.6e-11 42.9 0.0 8.5e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EIW79977.1 - 0.0012 19.0 0.1 0.0037 17.5 0.0 1.9 2 0 0 2 2 2 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EIW79977.1 - 0.0021 16.8 0.0 0.0045 15.7 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EIW79977.1 - 0.017 15.0 0.4 0.057 13.3 0.3 1.9 1 1 0 1 1 1 0 short chain dehydrogenase Semialdhyde_dh PF01118.19 EIW79977.1 - 0.089 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Herpes_gE PF02480.11 EIW79978.1 - 0.1 10.8 0.0 0.21 9.8 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E MFS_1 PF07690.11 EIW79979.1 - 3.3e-20 72.1 52.8 4e-13 48.8 20.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily ketoacyl-synt PF00109.21 EIW79980.1 - 8.4e-53 179.4 0.0 1.7e-52 178.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EIW79980.1 - 1.5e-39 136.2 1.0 2.4e-39 135.5 0.7 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EIW79980.1 - 1.7e-31 109.4 0.0 3.8e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EIW79980.1 - 2.3e-26 92.5 0.0 7.1e-26 90.9 0.0 1.9 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.17 EIW79980.1 - 1.9e-24 85.8 0.0 4.4e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EIW79980.1 - 9e-22 77.7 0.0 2.5e-20 73.0 0.0 2.8 2 0 0 2 2 2 1 short chain dehydrogenase Thioesterase PF00975.15 EIW79980.1 - 8.8e-13 49.0 0.0 2.5e-12 47.5 0.0 1.9 1 0 0 1 1 1 1 Thioesterase domain Thiolase_N PF00108.18 EIW79980.1 - 0.001 18.0 0.0 0.0023 16.9 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 EIW79980.1 - 0.0044 17.2 0.3 0.014 15.6 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EIW79981.1 - 1.1e-65 221.1 0.0 1.3e-65 220.9 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIW79981.1 - 1.7e-33 116.0 0.0 2.2e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW79981.1 - 3.6e-18 66.2 0.0 5.4e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EIW79981.1 - 3.8e-18 65.3 0.0 5e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EIW79981.1 - 4.2e-14 52.0 0.6 7.7e-11 41.3 0.1 2.2 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.10 EIW79981.1 - 7.8e-09 34.8 1.2 3.1e-08 32.8 0.8 1.8 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EIW79981.1 - 2.5e-07 30.7 0.4 7.6e-07 29.1 0.3 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW79981.1 - 4.4e-07 29.7 1.2 9.2e-06 25.4 0.8 2.5 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 EIW79981.1 - 0.0024 17.1 0.1 0.0052 16.0 0.1 1.4 1 1 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 EIW79981.1 - 0.054 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain p450 PF00067.17 EIW79982.1 - 1e-26 93.5 0.0 1.3e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 GMC_oxred_C PF05199.8 EIW79983.1 - 1.6e-32 112.7 0.0 3.2e-32 111.7 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase Erg28 PF03694.8 EIW79985.1 - 3.1e-34 117.2 4.1 3.9e-34 116.9 2.8 1.1 1 0 0 1 1 1 1 Erg28 like protein DUF4212 PF13937.1 EIW79985.1 - 0.24 11.4 2.8 0.18 11.7 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4212) DUF2631 PF10939.3 EIW79987.1 - 0.044 13.6 0.2 0.051 13.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2631) p450 PF00067.17 EIW79988.1 - 4.2e-75 253.0 0.0 5.8e-75 252.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EIW79989.1 - 1.1e-18 67.1 46.2 1.6e-12 46.8 11.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIW79989.1 - 2e-08 32.9 6.8 2e-08 32.9 4.7 1.9 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) PSI_PSAK PF01241.13 EIW79989.1 - 0.056 13.4 1.3 0.41 10.6 0.3 2.6 2 0 0 2 2 2 0 Photosystem I psaG / psaK p450 PF00067.17 EIW79990.1 - 6.3e-26 90.9 0.0 8.5e-26 90.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW79991.1 - 7.6e-33 113.7 0.0 4.3e-30 104.6 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 DUF4191 PF13829.1 EIW79992.1 - 4.5 6.3 11.0 1.9 7.5 0.7 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4191) 3Beta_HSD PF01073.14 EIW79993.1 - 1.4e-62 210.9 0.0 1.6e-62 210.7 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIW79993.1 - 2.1e-32 112.4 0.0 2.9e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW79993.1 - 2e-15 57.3 0.0 3.5e-15 56.4 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIW79993.1 - 3.7e-14 52.2 0.2 2.4e-10 39.7 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EIW79993.1 - 9.6e-13 47.6 0.0 1.3e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EIW79993.1 - 3e-07 29.6 1.8 4.7e-06 25.7 1.3 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EIW79993.1 - 3.8e-05 23.4 0.0 0.00012 21.8 0.0 1.9 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 EIW79993.1 - 6.9e-05 22.2 0.1 0.00011 21.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EIW79993.1 - 0.00011 22.1 0.1 0.00067 19.6 0.1 2.2 1 1 0 1 1 1 1 short chain dehydrogenase DUF4616 PF15394.1 EIW79993.1 - 0.065 12.2 0.0 0.085 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4616) UMPH-1 PF05822.7 EIW79993.1 - 0.19 11.0 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) GMC_oxred_C PF05199.8 EIW79994.1 - 5.2e-16 59.2 1.1 1.1e-13 51.6 0.1 2.7 2 1 1 3 3 3 2 GMC oxidoreductase GMC_oxred_N PF00732.14 EIW79994.1 - 1.6e-09 37.3 0.3 6.1e-09 35.4 0.2 1.8 1 1 0 1 1 1 1 GMC oxidoreductase NAD_binding_4 PF07993.7 EIW79995.1 - 1.5e-29 102.6 0.0 2.3e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EIW79995.1 - 9.8e-25 86.7 0.0 1.2e-23 83.2 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 EIW79995.1 - 2.2e-09 37.1 0.0 3.8e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EIW79995.1 - 0.0032 17.7 0.0 0.007 16.6 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.19 EIW79995.1 - 0.025 14.8 0.1 0.054 13.7 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EIW79995.1 - 0.12 12.3 2.2 0.33 10.8 0.5 2.6 3 1 0 3 3 3 0 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EIW79995.1 - 0.16 10.8 0.0 0.29 9.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GMC_oxred_N PF00732.14 EIW79996.1 - 1.3e-52 178.8 0.0 1.7e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIW79996.1 - 8e-32 110.5 0.0 1.6e-31 109.5 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIW79996.1 - 4.7e-07 29.0 0.0 0.0041 16.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW79996.1 - 1.7e-06 27.1 0.0 0.0053 15.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EIW79996.1 - 0.00029 19.8 0.0 0.00062 18.8 0.0 1.6 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EIW79996.1 - 0.0006 19.7 0.0 0.041 13.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW79996.1 - 0.00061 19.9 0.0 0.19 11.7 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW79996.1 - 0.0048 16.8 0.1 0.02 14.9 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EIW79996.1 - 0.015 13.8 0.0 0.087 11.2 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.13 EIW79996.1 - 0.11 12.5 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_9 PF13454.1 EIW79996.1 - 0.14 11.9 0.1 0.71 9.6 0.0 2.3 3 0 0 3 3 3 0 FAD-NAD(P)-binding Thi4 PF01946.12 EIW79996.1 - 0.15 11.1 0.1 0.46 9.5 0.0 1.7 2 0 0 2 2 2 0 Thi4 family UbiA PF01040.13 EIW79999.1 - 1.1e-29 103.3 18.2 4.8e-28 98.0 12.6 2.0 1 1 0 1 1 1 1 UbiA prenyltransferase family UreF PF01730.11 EIW79999.1 - 1.6 8.8 6.0 0.23 11.5 1.1 1.9 2 0 0 2 2 2 0 UreF DUF3329 PF11808.3 EIW79999.1 - 4.4 7.4 9.1 7.7 6.6 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3329) Peptidase_S39 PF02122.10 EIW80000.1 - 0.024 13.9 0.0 0.033 13.4 0.0 1.1 1 0 0 1 1 1 0 Peptidase S39 NAD_binding_4 PF07993.7 EIW80001.1 - 2.4e-31 108.5 0.0 4.9e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EIW80001.1 - 7.8e-25 87.1 0.0 1.2e-22 79.9 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.16 EIW80001.1 - 1.9e-12 47.1 0.0 3.6e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIW80001.1 - 2.3e-05 23.2 0.0 3.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EIW80001.1 - 0.0051 15.7 0.0 0.049 12.5 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain PP-binding PF00550.20 EIW80001.1 - 0.017 15.3 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 EIW80001.1 - 0.035 12.9 0.0 0.068 12.0 0.0 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 EIW80001.1 - 0.098 12.9 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EIW80001.1 - 1.8 8.4 5.5 0.96 9.3 0.4 3.0 3 1 0 3 3 3 0 short chain dehydrogenase p450 PF00067.17 EIW80005.1 - 7.4e-69 232.4 0.0 9.5e-69 232.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF775 PF05603.7 EIW80006.1 - 5.5e-17 61.9 0.0 5.8e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) HMGL-like PF00682.14 EIW80007.1 - 3e-45 154.7 0.1 3.2e-44 151.3 0.1 2.0 1 1 0 1 1 1 1 HMGL-like p450 PF00067.17 EIW80008.1 - 7.1e-70 235.7 0.0 8.7e-70 235.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HTH_41 PF14502.1 EIW80008.1 - 0.0099 15.4 0.0 0.026 14.1 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain DUF1129 PF06570.6 EIW80009.1 - 0.8 8.9 3.8 0.31 10.3 0.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1129) Tic20 PF09685.5 EIW80009.1 - 3.3 7.7 16.5 57 3.7 11.4 2.4 1 1 0 1 1 1 0 Tic20-like protein MFS_1 PF07690.11 EIW80011.1 - 3.8e-15 55.4 42.7 2.1e-11 43.1 10.0 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIW80011.1 - 1e-08 33.8 4.5 1e-08 33.8 3.1 2.1 1 1 1 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Epiglycanin_C PF14654.1 EIW80011.1 - 4.6 7.2 9.2 0.3 11.1 0.1 3.0 3 0 0 3 3 3 0 Mucin, catalytic, TM and cytoplasmic tail region OppC_N PF12911.2 EIW80013.1 - 0.088 12.1 2.5 3.7 7.0 0.4 2.6 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C APH PF01636.18 EIW80015.1 - 1.6e-09 37.8 0.0 6.1e-09 35.9 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EIW80015.1 - 1.7e-05 23.6 0.1 0.0026 16.4 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) NAD_binding_4 PF07993.7 EIW80016.1 - 0.049 12.5 0.0 0.065 12.1 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein SNF2_N PF00176.18 EIW80017.1 - 1.1e-71 241.1 0.0 1.5e-71 240.6 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW80017.1 - 3e-15 55.8 0.0 6e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW80017.1 - 0.00011 22.1 0.0 0.00032 20.5 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit NAD_binding_4 PF07993.7 EIW80018.1 - 2.5e-63 213.2 0.1 1.3e-30 106.1 0.0 2.3 2 0 0 2 2 2 2 Male sterility protein AMP-binding PF00501.23 EIW80018.1 - 1.2e-54 185.3 0.0 3.1e-30 104.8 0.0 3.2 2 2 0 2 2 2 2 AMP-binding enzyme Epimerase PF01370.16 EIW80018.1 - 2.3e-31 109.0 0.0 7.6e-15 54.9 0.0 3.1 3 0 0 3 3 3 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIW80018.1 - 1.9e-11 43.2 0.0 2.1e-05 23.3 0.0 2.8 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EIW80018.1 - 6.1e-10 39.2 3.8 2.6e-05 24.1 0.1 3.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EIW80018.1 - 4.4e-08 32.9 5.1 0.00027 20.6 0.0 3.1 3 0 0 3 3 3 2 KR domain PP-binding PF00550.20 EIW80018.1 - 3.4e-05 24.0 0.0 0.02 15.1 0.0 3.3 4 0 0 4 4 4 1 Phosphopantetheine attachment site Semialdhyde_dh PF01118.19 EIW80018.1 - 0.0017 18.6 0.4 2.9 8.2 0.0 2.8 2 0 0 2 2 2 2 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 EIW80018.1 - 0.0025 17.1 0.4 0.16 11.2 0.0 2.3 2 0 0 2 2 2 1 NmrA-like family DapB_N PF01113.15 EIW80018.1 - 0.008 16.0 1.1 1.3 8.9 0.1 2.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 EIW80018.1 - 0.042 12.7 0.1 2.3 7.0 0.0 2.7 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein APH PF01636.18 EIW80019.1 - 2.5e-10 40.4 0.0 1.6e-09 37.8 0.0 2.6 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EIW80019.1 - 6.3e-06 25.0 0.1 2.8e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1679) RIO1 PF01163.17 EIW80019.1 - 0.071 12.4 0.0 0.16 11.2 0.0 1.6 1 0 0 1 1 1 0 RIO1 family EST1_DNA_bind PF10373.4 EIW80021.1 - 3e-26 92.2 0.0 1e-25 90.5 0.0 1.8 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EIW80021.1 - 5.8e-10 39.2 0.0 3.1e-09 36.8 0.0 2.1 1 1 0 1 1 1 1 Telomerase activating protein Est1 TPR_11 PF13414.1 EIW80021.1 - 0.011 15.3 0.2 0.025 14.1 0.1 1.6 1 0 0 1 1 1 0 TPR repeat ArfGap PF01412.13 EIW80024.1 - 3.1e-41 139.8 0.0 5e-41 139.1 0.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Tnp_DNA_bind PF14706.1 EIW80024.1 - 0.083 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Transposase DNA-binding GMC_oxred_N PF00732.14 EIW80025.1 - 1.1e-48 165.8 0.0 1.5e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIW80025.1 - 2.2e-29 102.6 0.0 3.8e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_3 PF01494.14 EIW80026.1 - 5.2e-17 61.9 0.4 4.6e-12 45.6 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 EIW80026.1 - 7.6e-05 21.5 0.2 0.0018 16.9 0.0 2.1 1 1 1 2 2 2 1 Tryptophan halogenase NAD_binding_8 PF13450.1 EIW80026.1 - 0.00021 21.2 0.4 0.0021 18.0 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIW80026.1 - 0.00093 18.1 0.3 0.0024 16.8 0.2 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase SE PF08491.5 EIW80026.1 - 0.032 13.0 0.0 0.18 10.5 0.0 1.9 2 0 0 2 2 2 0 Squalene epoxidase Scaffolding_pro PF11418.3 EIW80028.1 - 0.0014 18.8 0.8 0.48 10.7 0.7 2.6 2 1 0 2 2 2 2 Phi29 scaffolding protein Helitron_like_N PF14214.1 EIW80029.1 - 6.2e-15 55.3 0.0 1.2e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus F-box PF00646.28 EIW80030.1 - 0.12 12.0 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 F-box domain Transposase_21 PF02992.9 EIW80031.1 - 3.3e-11 42.7 0.0 7.5e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EIW80031.1 - 0.022 14.1 0.0 0.046 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) SNAP-25 PF00835.14 EIW80035.1 - 0.095 13.4 2.0 0.25 12.1 1.4 1.7 1 0 0 1 1 1 0 SNAP-25 family zf-CCCH PF00642.19 EIW80036.1 - 3.4e-09 36.1 7.5 3e-08 33.1 2.6 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Choline_kinase PF01633.15 EIW80037.1 - 1.9e-14 53.7 0.0 2.7e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EIW80037.1 - 0.0084 15.8 0.1 0.016 14.9 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Tet_JBP PF12851.2 EIW80038.1 - 1.2e-05 24.6 0.0 1.4e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Abhydrolase_6 PF12697.2 EIW80039.1 - 1.9e-20 73.7 2.2 2.7e-20 73.2 1.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW80039.1 - 3.4e-08 33.3 1.3 5.9e-08 32.5 0.9 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1737 PF08410.5 EIW80039.1 - 0.006 16.3 0.0 0.023 14.4 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1737) Abhydrolase_1 PF00561.15 EIW80039.1 - 0.0083 15.7 2.1 0.0083 15.7 1.5 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Spore_YhcN_YlaJ PF09580.5 EIW80039.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.3 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Mito_carr PF00153.22 EIW80042.1 - 7.2e-16 57.6 0.0 1.4e-09 37.5 0.0 3.0 2 1 0 2 2 2 2 Mitochondrial carrier protein RSN1_TM PF13967.1 EIW80042.1 - 0.00081 18.9 1.1 0.002 17.6 0.1 2.1 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport Mito_carr PF00153.22 EIW80043.1 - 1e-09 37.9 0.0 3.5e-09 36.2 0.0 1.9 1 1 0 1 1 1 1 Mitochondrial carrier protein Terpene_synth_C PF03936.11 EIW80046.1 - 3.6e-09 36.2 1.0 4.3e-09 36.0 0.1 1.6 1 1 1 2 2 2 1 Terpene synthase family, metal binding domain TRI5 PF06330.6 EIW80046.1 - 0.019 13.6 0.1 0.025 13.2 0.1 1.2 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) zf-rbx1 PF12678.2 EIW80047.1 - 5.5e-34 116.1 13.7 6.8e-34 115.8 9.5 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EIW80047.1 - 3.8e-16 58.7 9.5 4.9e-16 58.3 6.6 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EIW80047.1 - 1.3e-06 28.1 12.5 7.5e-06 25.6 8.7 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIW80047.1 - 0.00075 19.1 11.6 0.015 14.9 8.1 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW80047.1 - 0.003 17.1 9.9 0.014 15.0 3.0 2.4 1 1 1 2 2 2 2 Zinc finger, C3HC4 type (RING finger) VSP PF03302.8 EIW80047.1 - 0.025 13.2 2.2 0.026 13.1 1.5 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein zf-C3HC4_2 PF13923.1 EIW80047.1 - 0.047 13.7 12.6 1.2 9.2 8.7 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EIW80047.1 - 0.4 10.6 9.9 1.5 8.7 6.8 1.9 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H PF13771.1 EIW80047.1 - 0.58 10.3 10.1 45 4.2 7.1 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_UBOX PF13445.1 EIW80047.1 - 0.84 9.4 7.1 0.98 9.1 1.6 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-HC5HC2H_2 PF13832.1 EIW80047.1 - 0.91 9.5 10.0 3.3 7.7 6.9 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain zf-RING_5 PF14634.1 EIW80047.1 - 1.7 8.3 11.4 12 5.7 7.9 2.3 1 1 0 1 1 1 0 zinc-RING finger domain Cauli_AT PF03233.8 EIW80048.1 - 1.1 8.9 0.9 36 4.0 0.0 2.6 2 0 0 2 2 2 0 Aphid transmission protein Peptidase_M28 PF04389.12 EIW80051.1 - 2.9e-25 89.0 0.0 4.5e-25 88.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EIW80051.1 - 6.2e-07 29.1 0.1 9.2e-07 28.5 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Terpene_synth_C PF03936.11 EIW80053.1 - 5.8e-10 38.8 0.1 8.3e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Dus PF01207.12 EIW80054.1 - 5e-52 176.6 0.0 8.7e-52 175.8 0.0 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EIW80054.1 - 0.0024 17.5 7.5 0.005 16.4 0.2 3.1 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AOX PF01786.12 EIW80055.1 - 0.068 12.5 0.9 0.085 12.2 0.2 1.5 1 1 1 2 2 2 0 Alternative oxidase NfeD PF01957.13 EIW80056.1 - 4.2 7.5 12.1 25 4.9 2.0 3.3 2 1 2 4 4 4 0 NfeD-like C-terminal, partner-binding zf-LITAF-like PF10601.4 EIW80056.1 - 5 7.0 6.9 1.5 8.6 0.1 2.7 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Peptidase_M20 PF01546.23 EIW80058.1 - 5.2e-31 107.6 0.0 8.1e-31 107.0 0.0 1.3 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIW80058.1 - 1.3e-13 50.6 0.0 2.4e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Aminotran_1_2 PF00155.16 EIW80061.1 - 2.9e-55 187.6 0.0 3.9e-43 147.7 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIW80061.1 - 0.00011 21.4 0.0 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase OKR_DC_1 PF01276.15 EIW80061.1 - 0.0081 14.7 0.0 0.016 13.7 0.0 1.4 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_5 PF00266.14 EIW80061.1 - 0.053 12.2 0.0 0.091 11.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V TPR_10 PF13374.1 EIW80062.1 - 8.5e-63 206.6 0.2 3.5e-16 58.5 0.0 4.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 EIW80062.1 - 4.5e-51 170.6 0.3 4.3e-17 61.8 0.0 3.9 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.1 EIW80062.1 - 6.8e-15 54.4 0.3 1e-05 25.0 0.0 2.6 1 1 3 4 4 4 3 TPR repeat TPR_7 PF13176.1 EIW80062.1 - 4e-13 48.0 0.0 0.018 14.7 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIW80062.1 - 9.1e-12 45.3 0.0 0.00036 21.1 0.0 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIW80062.1 - 2.6e-11 42.7 0.2 0.57 10.5 0.0 4.4 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.23 EIW80062.1 - 2e-10 39.7 0.5 0.41 10.3 0.0 4.2 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 EIW80062.1 - 8.7e-08 31.5 0.0 2.4 8.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIW80062.1 - 4.6e-07 30.0 0.9 0.00098 19.4 0.3 3.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_4 PF07721.9 EIW80062.1 - 1.7e-05 24.8 0.0 0.43 11.1 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF59 PF01883.14 EIW80062.1 - 0.00051 19.9 0.0 8.8 6.4 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function DUF59 TPR_20 PF14561.1 EIW80062.1 - 0.00082 19.4 0.4 0.86 9.7 0.0 3.5 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIW80062.1 - 0.0049 16.5 0.4 12 5.9 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIW80062.1 - 0.005 17.3 1.4 14 6.6 0.0 4.0 1 1 3 4 4 4 0 Tetratricopeptide repeat A2M PF00207.17 EIW80062.1 - 0.0073 15.8 0.0 7.3 6.2 0.0 3.5 1 1 2 3 3 3 0 Alpha-2-macroglobulin family Trans_reg_C PF00486.23 EIW80062.1 - 0.0091 15.8 0.1 0.27 11.1 0.0 2.7 1 1 2 3 3 3 1 Transcriptional regulatory protein, C terminal TPR_5 PF12688.2 EIW80062.1 - 0.0095 15.9 3.1 0.56 10.2 0.1 2.6 1 1 2 3 3 3 1 Tetratrico peptide repeat TPR_3 PF07720.7 EIW80062.1 - 0.013 15.2 0.2 1.3 8.9 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2680 PF10925.3 EIW80062.1 - 0.022 14.5 3.3 22 5.0 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) Opiods_neuropep PF01160.13 EIW80062.1 - 0.12 12.1 0.5 22 4.8 0.0 3.0 3 0 0 3 3 3 0 Vertebrate endogenous opioids neuropeptide TPR_6 PF13174.1 EIW80062.1 - 0.22 12.0 2.2 3.9 8.1 0.0 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat Cytochrom_B562 PF07361.6 EIW80062.1 - 1.7 9.0 6.0 55 4.2 0.0 3.3 2 1 0 2 2 2 0 Cytochrome b562 Patatin PF01734.17 EIW80063.1 - 1.1e-19 71.1 0.2 1.7e-19 70.6 0.1 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase AAA_19 PF13245.1 EIW80063.1 - 0.0096 15.6 0.0 0.028 14.1 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain PhoH PF02562.11 EIW80063.1 - 0.028 13.6 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.1 EIW80063.1 - 0.03 14.3 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.7 EIW80063.1 - 0.054 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 EIW80063.1 - 0.11 12.1 0.0 0.25 10.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 EIW80063.1 - 0.12 12.4 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF4328 PF14219.1 EIW80064.1 - 0.029 13.6 0.0 0.039 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Aminotran_1_2 PF00155.16 EIW80069.1 - 7.3e-34 117.2 0.0 2.2e-31 109.1 0.0 2.7 2 1 0 2 2 2 2 Aminotransferase class I and II OKR_DC_1 PF01276.15 EIW80069.1 - 0.042 12.3 0.0 0.097 11.1 0.0 1.5 1 1 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain TPR_10 PF13374.1 EIW80070.1 - 3.3e-64 211.1 4.8 9.8e-15 53.9 0.0 5.1 5 0 0 5 5 5 5 Tetratricopeptide repeat TPR_12 PF13424.1 EIW80070.1 - 4.2e-59 196.4 6.8 1.3e-19 69.8 0.1 3.9 1 1 4 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 EIW80070.1 - 3.9e-14 52.0 0.0 2.8e-06 26.8 0.0 2.6 2 1 1 3 3 3 3 TPR repeat TPR_7 PF13176.1 EIW80070.1 - 1.1e-11 43.5 1.3 0.093 12.5 0.0 4.5 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIW80070.1 - 1.6e-11 44.5 0.0 0.00032 21.2 0.1 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_4 PF07721.9 EIW80070.1 - 1.4e-10 40.5 0.0 0.037 14.4 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIW80070.1 - 1.4e-10 40.2 0.1 0.18 11.8 0.0 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 EIW80070.1 - 2.4e-10 39.7 0.0 0.25 11.6 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EIW80070.1 - 3.3e-10 39.1 1.3 0.13 11.8 0.0 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_3 PF07720.7 EIW80070.1 - 4.5e-08 32.7 0.5 0.011 15.5 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIW80070.1 - 3.7e-06 27.1 3.8 0.23 11.8 0.1 3.5 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIW80070.1 - 7.5e-06 25.3 0.8 3.7 7.5 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_5 PF12688.2 EIW80070.1 - 1e-05 25.5 3.0 0.03 14.3 0.1 2.4 1 1 0 2 2 2 2 Tetratrico peptide repeat DUF2664 PF10867.3 EIW80070.1 - 0.00013 22.4 3.6 13 6.4 0.1 5.0 3 2 2 5 5 5 0 Protein of unknown function (DUF2664) DUF59 PF01883.14 EIW80070.1 - 0.00029 20.7 0.1 10 6.1 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function DUF59 TPR_14 PF13428.1 EIW80070.1 - 0.00065 20.1 3.8 9.1 7.2 0.0 4.4 1 1 3 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIW80070.1 - 0.00065 19.9 4.4 6.4 7.4 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 EIW80070.1 - 0.0011 18.9 3.3 1 9.4 0.0 3.9 1 1 3 4 4 4 1 Tetratricopeptide repeat PPR_1 PF12854.2 EIW80070.1 - 0.016 14.6 1.5 24 4.5 0.0 3.5 3 0 0 3 3 3 0 PPR repeat Dimer_Tnp_Tn5 PF02281.11 EIW80070.1 - 0.027 14.5 3.0 3.2 7.9 0.0 3.1 1 1 2 3 3 3 0 Transposase Tn5 dimerisation domain Cytochrom_B562 PF07361.6 EIW80070.1 - 0.051 13.9 3.7 23 5.4 0.0 3.5 3 1 0 3 3 3 0 Cytochrome b562 Gag_p30 PF02093.11 EIW80070.1 - 0.08 12.1 3.3 18 4.4 0.0 3.7 1 1 3 4 4 4 0 Gag P30 core shell protein DUF2680 PF10925.3 EIW80070.1 - 3.9 7.4 9.6 28 4.6 0.3 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2680) TPR_10 PF13374.1 EIW80071.1 - 3.6e-23 80.7 0.5 6.4e-14 51.3 0.0 2.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIW80071.1 - 1.1e-15 57.3 0.1 1.2e-15 57.1 0.1 1.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_4 PF07721.9 EIW80071.1 - 9.6e-09 34.8 0.1 0.0056 16.9 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIW80071.1 - 4.2e-07 29.2 0.4 0.011 15.4 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIW80071.1 - 1.2e-06 28.0 0.0 1.5e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 EIW80071.1 - 4.1e-06 26.1 0.0 0.099 12.2 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_3 PF07720.7 EIW80071.1 - 6.6e-06 25.8 0.0 0.14 11.9 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIW80071.1 - 6.7e-06 26.6 0.0 1.2e-05 25.8 0.0 1.4 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIW80071.1 - 3e-05 23.6 0.1 0.3 11.1 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIW80071.1 - 0.00012 21.6 0.1 0.57 10.0 0.0 2.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIW80071.1 - 0.00015 22.0 3.9 0.0019 18.4 0.4 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIW80071.1 - 0.00018 21.4 0.1 0.37 11.0 0.0 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIW80071.1 - 0.0004 20.7 0.3 1.1 10.1 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat PPR_1 PF12854.2 EIW80071.1 - 0.012 15.1 0.4 5.2 6.6 0.0 2.2 2 0 0 2 2 2 0 PPR repeat PPR PF01535.15 EIW80071.1 - 0.036 14.0 0.0 12 6.1 0.0 2.3 2 0 0 2 2 2 0 PPR repeat TPR_5 PF12688.2 EIW80071.1 - 0.041 13.9 0.2 0.69 9.9 0.1 2.0 1 1 0 1 1 1 0 Tetratrico peptide repeat Cytochrom_B562 PF07361.6 EIW80071.1 - 0.092 13.1 0.5 13 6.2 0.1 2.0 2 0 0 2 2 2 0 Cytochrome b562 TPR_21 PF09976.4 EIW80071.1 - 0.11 12.4 0.3 0.44 10.4 0.2 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat Dimer_Tnp_Tn5 PF02281.11 EIW80071.1 - 0.14 12.2 0.2 7.3 6.7 0.0 2.0 1 1 1 2 2 2 0 Transposase Tn5 dimerisation domain TPR_6 PF13174.1 EIW80071.1 - 0.2 12.1 0.8 19 6.0 0.1 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EIW80072.1 - 1.5e-46 155.0 6.7 1.7e-15 56.3 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EIW80072.1 - 2.6e-39 133.0 2.5 9.3e-18 63.9 0.1 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EIW80072.1 - 3.4e-16 58.6 0.3 4e-06 26.3 0.0 2.8 1 1 2 3 3 3 3 TPR repeat TPR_7 PF13176.1 EIW80072.1 - 7.4e-11 41.0 0.7 0.025 14.3 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_4 PF07721.9 EIW80072.1 - 7.6e-11 41.3 0.1 0.018 15.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIW80072.1 - 9.2e-11 42.1 0.2 4.8e-06 27.0 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIW80072.1 - 4.8e-10 38.6 0.4 0.038 13.5 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIW80072.1 - 6.9e-10 38.3 0.6 0.047 13.9 0.1 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIW80072.1 - 8.3e-09 34.7 0.3 0.043 13.7 0.0 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_3 PF07720.7 EIW80072.1 - 6.1e-06 25.9 0.1 0.42 10.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIW80072.1 - 1.2e-05 24.6 0.5 1.6 8.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIW80072.1 - 6.2e-05 23.2 0.9 3.5 8.5 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIW80072.1 - 8.1e-05 22.8 6.6 0.039 14.3 1.1 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat PPR PF01535.15 EIW80072.1 - 0.00053 19.7 0.0 13 5.9 0.0 3.4 3 0 0 3 3 3 0 PPR repeat DUF59 PF01883.14 EIW80072.1 - 0.0006 19.7 0.0 5.7 6.9 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF59 PPR_1 PF12854.2 EIW80072.1 - 0.0013 18.1 2.7 7.5 6.1 0.1 3.3 3 0 0 3 3 3 0 PPR repeat Gag_p30 PF02093.11 EIW80072.1 - 0.0016 17.7 2.0 4.1 6.5 0.1 3.0 1 1 2 3 3 3 1 Gag P30 core shell protein UPF0240 PF06784.6 EIW80072.1 - 0.0057 16.3 0.4 1.9 8.1 0.0 2.8 1 1 2 3 3 3 1 Uncharacterised protein family (UPF0240) DUF2664 PF10867.3 EIW80072.1 - 0.0063 17.1 0.5 20 5.8 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2664) DUF2680 PF10925.3 EIW80072.1 - 0.01 15.6 3.9 5.6 6.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) Apc3 PF12895.2 EIW80072.1 - 0.013 15.5 0.0 1.5 8.9 0.0 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 CPSase_L_chain PF00289.17 EIW80072.1 - 0.045 13.8 0.0 66 3.6 0.0 3.0 3 0 0 3 3 3 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Cytochrom_B562 PF07361.6 EIW80072.1 - 0.047 14.1 3.8 6.3 7.2 0.0 3.1 2 1 1 3 3 3 0 Cytochrome b562 Trans_reg_C PF00486.23 EIW80072.1 - 0.057 13.3 0.2 1 9.3 0.0 2.5 1 1 2 3 3 3 0 Transcriptional regulatory protein, C terminal Opiods_neuropep PF01160.13 EIW80072.1 - 0.072 12.8 0.6 4 7.2 0.0 2.9 3 0 0 3 3 3 0 Vertebrate endogenous opioids neuropeptide DPM3 PF08285.6 EIW80072.1 - 0.073 12.9 2.0 22 4.9 0.0 3.0 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Dimer_Tnp_Tn5 PF02281.11 EIW80072.1 - 0.085 12.9 2.1 12 6.1 0.1 2.9 1 1 2 3 3 3 0 Transposase Tn5 dimerisation domain DUF3368 PF11848.3 EIW80072.1 - 0.11 12.0 1.1 32 4.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF3368) TPR_5 PF12688.2 EIW80072.1 - 0.14 12.1 2.3 2.1 8.4 0.4 2.6 1 1 2 3 3 3 0 Tetratrico peptide repeat TPR_6 PF13174.1 EIW80072.1 - 0.19 12.2 2.7 34 5.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF217 PF02697.9 EIW80072.1 - 0.31 11.3 1.5 35 4.7 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized ACR, COG1753 DUF1897 PF09005.5 EIW80072.1 - 0.42 10.0 1.4 25 4.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF1897) Mei4 PF13971.1 EIW80072.1 - 0.71 8.7 7.1 7.3 5.4 0.2 2.9 1 1 2 3 3 3 0 Meiosis-specific protein Mei4 FliT PF05400.8 EIW80072.1 - 1.4 9.3 5.3 18 5.8 0.3 2.9 1 1 2 3 3 3 0 Flagellar protein FliT NEMO PF11577.3 EIW80072.1 - 5.5 6.8 9.1 4.3 7.1 0.1 3.2 3 1 1 4 4 3 0 NF-kappa-B essential modulator NEMO Patatin PF01734.17 EIW80073.1 - 8.3e-19 68.3 0.1 1.2e-18 67.8 0.1 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase AAA_16 PF13191.1 EIW80073.1 - 0.0022 17.9 0.0 0.0044 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EIW80073.1 - 0.01 15.5 0.0 0.03 14.0 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EIW80073.1 - 0.052 13.2 0.0 0.088 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 EIW80073.1 - 0.067 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIW80073.1 - 0.079 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 EIW80073.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase TLE_N PF03920.10 EIW80073.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain UPF0079 PF02367.12 EIW80073.1 - 0.14 11.7 0.0 0.42 10.2 0.0 1.8 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 EIW80073.1 - 0.16 11.1 0.0 0.3 10.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein TPR_10 PF13374.1 EIW80076.1 - 1.1e-84 276.1 0.3 5.2e-13 48.4 0.0 7.1 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.1 EIW80076.1 - 3.3e-66 219.1 4.3 6.2e-15 54.9 0.0 4.7 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.1 EIW80076.1 - 1e-20 73.1 0.7 0.00025 20.6 0.0 4.8 2 1 3 5 5 5 5 TPR repeat TPR_1 PF00515.23 EIW80076.1 - 4e-19 67.3 4.5 0.18 11.4 0.0 7.3 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.12 EIW80076.1 - 1.1e-18 65.5 2.8 0.54 10.2 0.0 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.1 EIW80076.1 - 7.5e-17 59.7 3.9 0.072 12.9 0.0 7.3 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIW80076.1 - 1.5e-14 52.8 4.9 0.24 11.6 0.0 7.2 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EIW80076.1 - 1.3e-13 51.2 0.0 0.0046 17.5 0.0 5.2 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_4 PF07721.9 EIW80076.1 - 3.9e-12 45.3 0.0 0.035 14.5 0.0 7.0 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIW80076.1 - 1.2e-07 30.9 5.5 7.6 6.5 0.0 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_19 PF14559.1 EIW80076.1 - 1.3e-07 31.8 8.1 0.18 12.1 0.0 5.0 2 2 4 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIW80076.1 - 3.2e-07 30.3 7.2 5.7 7.8 0.1 6.4 3 3 3 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EIW80076.1 - 8.6e-07 29.0 0.2 0.87 9.7 0.0 4.3 1 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 Trans_reg_C PF00486.23 EIW80076.1 - 1.4e-06 28.0 0.1 0.31 10.9 0.0 3.6 2 1 1 3 3 3 2 Transcriptional regulatory protein, C terminal TPR_3 PF07720.7 EIW80076.1 - 8.8e-06 25.3 0.1 3.4 7.5 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.1 EIW80076.1 - 0.00035 20.6 2.8 15 5.7 0.0 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat PPR PF01535.15 EIW80076.1 - 0.0047 16.8 2.0 24 5.1 0.0 5.2 6 0 0 6 6 5 0 PPR repeat Ribosomal_S7 PF00177.16 EIW80076.1 - 0.11 12.0 0.1 3 7.4 0.0 2.7 2 1 1 3 3 3 0 Ribosomal protein S7p/S5e TPR_6 PF13174.1 EIW80076.1 - 0.21 12.0 8.4 60 4.4 0.0 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat NEMO PF11577.3 EIW80076.1 - 0.88 9.3 5.8 16 5.3 0.1 3.7 4 0 0 4 4 3 0 NF-kappa-B essential modulator NEMO Cytochrom_B562 PF07361.6 EIW80076.1 - 2.1 8.8 9.1 77 3.7 0.2 4.7 5 1 1 6 6 5 0 Cytochrome b562 Patatin PF01734.17 EIW80077.1 - 6.3e-18 65.4 0.3 1.7e-17 64.0 0.2 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase AAA_16 PF13191.1 EIW80077.1 - 0.0046 16.9 0.0 0.0087 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EIW80077.1 - 0.011 15.4 0.0 0.038 13.7 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EIW80077.1 - 0.038 13.6 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 EIW80077.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EIW80077.1 - 0.12 12.0 0.0 0.34 10.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EIW80077.1 - 0.12 12.0 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Zeta_toxin PF06414.7 EIW80077.1 - 0.16 11.0 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin Complex1_LYR PF05347.10 EIW80078.1 - 0.00086 19.0 7.5 0.004 16.9 0.1 3.2 3 0 0 3 3 3 2 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EIW80078.1 - 0.057 13.6 10.4 0.14 12.3 0.4 3.7 3 1 0 3 3 3 0 Complex1_LYR-like Thaumatin PF00314.12 EIW80079.1 - 3.3e-12 46.3 8.5 4.1e-12 46.0 5.9 1.2 1 0 0 1 1 1 1 Thaumatin family Glyco_hydro_30 PF02055.11 EIW80081.1 - 1.2e-26 92.9 1.7 1.7e-26 92.5 1.2 1.1 1 0 0 1 1 1 1 O-Glycosyl hydrolase family 30 DUF2513 PF10711.4 EIW80082.1 - 0.13 12.3 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) 4HBT PF03061.17 EIW80083.1 - 2.9e-12 46.5 0.1 5.5e-12 45.6 0.0 1.5 2 0 0 2 2 2 1 Thioesterase superfamily 4HBT_2 PF13279.1 EIW80083.1 - 6.3e-06 26.6 0.0 7.7e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl-ACP_TE PF01643.12 EIW80083.1 - 0.0015 17.5 0.0 0.0028 16.6 0.0 1.5 2 0 0 2 2 2 1 Acyl-ACP thioesterase Fungal_trans PF04082.13 EIW80084.1 - 3.8e-37 127.5 0.0 6.8e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW80084.1 - 6.6e-06 25.9 12.7 1.1e-05 25.2 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tropomyosin_1 PF12718.2 EIW80085.1 - 0.0066 16.3 4.3 0.0066 16.3 3.0 1.6 2 0 0 2 2 2 1 Tropomyosin like DUF3287 PF11690.3 EIW80085.1 - 0.019 15.0 0.2 0.038 14.0 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3287) IncA PF04156.9 EIW80085.1 - 0.06 12.9 6.2 0.091 12.3 4.3 1.2 1 0 0 1 1 1 0 IncA protein DUF4164 PF13747.1 EIW80085.1 - 0.11 12.6 7.6 0.24 11.5 3.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Macoilin PF09726.4 EIW80085.1 - 0.2 9.8 7.5 0.3 9.3 5.2 1.2 1 0 0 1 1 1 0 Transmembrane protein PIN_2 PF10130.4 EIW80085.1 - 0.27 11.2 2.7 0.53 10.3 1.8 1.5 1 0 0 1 1 1 0 PIN domain DivIVA PF05103.8 EIW80085.1 - 3.1 7.8 11.3 0.97 9.4 5.8 1.7 1 1 1 2 2 2 0 DivIVA protein Macoilin PF09726.4 EIW80086.1 - 0.0035 15.7 4.7 0.0043 15.4 3.3 1.0 1 0 0 1 1 1 1 Transmembrane protein DUF1572 PF07609.6 EIW80086.1 - 0.011 15.2 0.1 0.019 14.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1572) IF-2B PF01008.12 EIW80086.1 - 0.02 13.8 0.4 0.24 10.3 0.5 2.0 2 0 0 2 2 2 0 Initiation factor 2 subunit family Spc7 PF08317.6 EIW80086.1 - 0.022 13.4 2.7 0.037 12.7 1.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Tropomyosin PF00261.15 EIW80086.1 - 0.079 12.0 4.2 0.12 11.4 2.9 1.2 1 0 0 1 1 1 0 Tropomyosin OmpH PF03938.9 EIW80086.1 - 3.2 7.6 9.7 4.2 7.2 6.3 1.5 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF2513 PF10711.4 EIW80088.1 - 0.0089 16.0 0.0 0.016 15.3 0.0 1.3 1 0 0 1 1 1 1 Hypothetical protein (DUF2513) LPP PF04728.8 EIW80090.1 - 0.0006 19.5 2.6 0.57 10.0 0.2 2.5 2 0 0 2 2 2 2 Lipoprotein leucine-zipper Tropomyosin_1 PF12718.2 EIW80090.1 - 0.0022 17.8 6.3 0.019 14.8 0.4 2.3 2 0 0 2 2 2 2 Tropomyosin like Surfac_D-trimer PF09006.6 EIW80090.1 - 0.038 13.7 0.8 0.59 9.9 0.1 2.5 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation Sirohm_synth_C PF14823.1 EIW80090.1 - 0.041 13.1 0.1 0.12 11.7 0.1 1.8 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal DUF4618 PF15397.1 EIW80090.1 - 0.049 12.9 2.2 0.087 12.1 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) DUF3166 PF11365.3 EIW80090.1 - 0.088 13.2 4.3 0.33 11.4 2.7 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3166) FUSC PF04632.7 EIW80090.1 - 0.37 9.1 1.6 0.49 8.7 1.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family IFT57 PF10498.4 EIW80090.1 - 0.46 9.1 4.8 1.4 7.5 0.6 2.0 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Macoilin PF09726.4 EIW80090.1 - 5.5 5.1 11.6 10 4.2 8.0 1.4 1 1 0 1 1 1 0 Transmembrane protein TPR_MLP1_2 PF07926.7 EIW80090.1 - 6.1 6.5 15.6 4.8 6.9 0.9 2.9 2 1 0 3 3 3 0 TPR/MLP1/MLP2-like protein Tropomyosin PF00261.15 EIW80091.1 - 0.001 18.2 3.6 0.0017 17.5 2.5 1.3 1 0 0 1 1 1 1 Tropomyosin SCP-1 PF05483.7 EIW80091.1 - 0.051 11.3 0.4 0.069 10.9 0.3 1.1 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) DUF4201 PF13870.1 EIW80091.1 - 0.069 12.5 0.7 0.12 11.8 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Phage_GP20 PF06810.6 EIW80091.1 - 0.16 11.4 0.9 0.27 10.6 0.6 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 Lipid_DES PF08557.5 EIW80091.1 - 0.17 11.1 1.9 0.36 10.0 0.1 2.2 2 0 0 2 2 2 0 Sphingolipid Delta4-desaturase (DES) Mut7-C PF01927.11 EIW80092.1 - 0.15 12.0 1.5 0.24 11.3 1.0 1.3 1 0 0 1 1 1 0 Mut7-C RNAse domain Fer2 PF00111.22 EIW80093.1 - 4.1e-10 39.2 0.1 6.4e-10 38.6 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain PQ-loop PF04193.9 EIW80094.1 - 8.5e-20 70.0 8.7 4.5e-11 42.1 1.0 3.4 4 1 1 5 5 5 2 PQ loop repeat DUF2518 PF10726.4 EIW80094.1 - 5 6.6 11.9 23 4.5 0.3 3.8 3 1 1 4 4 4 0 Protein of function (DUF2518) Adap_comp_sub PF00928.16 EIW80095.1 - 2.5e-89 298.8 0.0 3.9e-89 298.2 0.0 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EIW80095.1 - 5.2e-07 29.4 0.3 8.6e-07 28.7 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Mon1 PF03164.9 EIW80095.1 - 0.018 13.6 0.0 0.026 13.1 0.0 1.2 1 0 0 1 1 1 0 Trafficking protein Mon1 SH3_5 PF08460.5 EIW80095.1 - 0.12 12.3 0.1 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain Peptidase_C48 PF02902.14 EIW80097.1 - 1.4e-05 24.8 0.1 3.4e-05 23.5 0.1 1.6 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain DUF3245 PF11595.3 EIW80097.1 - 0.53 10.5 3.3 1.4 9.2 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Dimer_Tnp_hAT PF05699.9 EIW80099.1 - 6.3e-05 22.5 0.0 6.5e-05 22.4 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF3450 PF11932.3 EIW80100.1 - 0.014 14.7 4.0 0.025 13.8 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Retrotrans_gag PF03732.12 EIW80100.1 - 0.092 12.8 0.1 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein GOLGA2L5 PF15070.1 EIW80100.1 - 0.12 10.8 1.8 0.17 10.3 1.2 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 zf-CCHC PF00098.18 EIW80100.1 - 0.19 11.7 3.3 0.61 10.1 2.3 1.9 1 1 0 1 1 1 0 Zinc knuckle HSP70 PF00012.15 EIW80105.1 - 0.0005 18.1 0.1 0.00056 17.9 0.1 1.0 1 0 0 1 1 1 1 Hsp70 protein DUF551 PF04448.7 EIW80107.1 - 0.0045 17.6 0.1 0.0075 17.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF551) UBN2_2 PF14227.1 EIW80108.1 - 2.9e-05 23.6 0.0 7.3e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIW80108.1 - 5e-05 23.0 0.0 9.2e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type SRC-1 PF08832.5 EIW80109.1 - 0.15 12.8 0.0 0.2 12.4 0.0 1.2 1 0 0 1 1 1 0 Steroid receptor coactivator RVT_2 PF07727.9 EIW80111.1 - 7.3e-13 48.0 0.0 8e-13 47.9 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1817 PF08847.6 EIW80111.1 - 0.056 13.0 0.0 0.057 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1817) TcdB_N PF12918.2 EIW80112.1 - 0.03 14.3 0.0 0.068 13.2 0.0 1.5 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain Alpha_kinase PF02816.13 EIW80120.1 - 1.3e-09 38.0 0.1 2e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Alpha-kinase family WD40 PF00400.27 EIW80121.1 - 1.2e-23 82.1 12.6 9.3e-08 31.6 0.0 6.8 6 1 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EIW80121.1 - 0.00021 21.0 0.1 0.017 14.8 0.0 3.1 1 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Mid2 PF04478.7 EIW80122.1 - 0.037 13.4 0.0 0.083 12.2 0.0 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Herpes_gE PF02480.11 EIW80122.1 - 0.088 11.0 0.0 0.14 10.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E YL1 PF05764.8 EIW80123.1 - 0.15 11.6 4.6 0.2 11.2 3.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF1378 PF07125.6 EIW80124.1 - 0.13 12.1 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) Transposase_21 PF02992.9 EIW80125.1 - 3.4e-16 59.0 0.0 5.8e-16 58.2 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EIW80125.1 - 0.17 11.3 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) HypA PF01155.14 EIW80125.1 - 0.55 9.9 0.9 22 4.7 0.1 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn-ribbon_8 PF09723.5 EIW80125.1 - 0.74 9.8 4.3 19 5.3 0.4 2.7 2 0 0 2 2 2 0 Zinc ribbon domain zf-AD PF07776.10 EIW80127.1 - 0.071 13.1 0.3 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 Zinc-finger associated domain (zf-AD) Glyco_hydro_28 PF00295.12 EIW80129.1 - 4.5e-36 124.4 0.0 1.9e-35 122.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EIW80129.1 - 2.6 7.7 13.4 0.87 9.3 6.5 2.4 2 1 0 2 2 2 0 Right handed beta helix region Lipoprotein_5 PF01298.13 EIW80130.1 - 0.3 10.0 0.4 0.42 9.5 0.3 1.1 1 0 0 1 1 1 0 Transferrin binding protein-like solute binding protein F-box-like PF12937.2 EIW80131.1 - 0.00016 21.3 0.2 0.0006 19.4 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW80131.1 - 0.00025 20.6 0.2 0.00078 19.0 0.2 1.8 1 0 0 1 1 1 1 F-box domain PDDEXK_1 PF12705.2 EIW80131.1 - 0.04 13.3 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily RhoGAP PF00620.22 EIW80132.1 - 2.3e-09 37.0 0.0 2e-08 34.0 0.0 2.1 1 1 0 1 1 1 1 RhoGAP domain Glyco_hydro_16 PF00722.16 EIW80134.1 - 4.1e-08 32.7 0.0 6.9e-08 31.9 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 zf-CCCH PF00642.19 EIW80135.1 - 7.3e-08 31.9 2.6 7.3e-08 31.9 1.8 2.1 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EIW80135.1 - 0.048 13.6 1.4 0.048 13.6 1.0 1.8 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Pinin_SDK_memA PF04696.8 EIW80136.1 - 2.8e-11 43.1 7.1 2.8e-11 43.1 4.9 3.2 3 0 0 3 3 3 2 pinin/SDK/memA/ protein conserved region DUF2894 PF11445.3 EIW80136.1 - 2.3 8.4 22.6 0.8 9.9 3.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2894) AAA_11 PF13086.1 EIW80136.1 - 4.7 6.7 9.4 0.35 10.3 1.5 2.0 2 0 0 2 2 2 0 AAA domain Borrelia_P83 PF05262.6 EIW80136.1 - 4.8 5.3 27.4 1.1 7.4 2.5 2.1 2 0 0 2 2 2 0 Borrelia P83/100 protein TPR_16 PF13432.1 EIW80137.1 - 2.8e-08 34.1 1.0 0.0092 16.6 0.5 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIW80137.1 - 3.2e-07 30.5 1.5 7.3e-05 23.0 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat SRP72 PF08492.7 EIW80137.1 - 2.3e-06 27.8 0.7 2.3e-06 27.8 0.5 2.4 2 0 0 2 2 2 1 SRP72 RNA-binding domain Apc3 PF12895.2 EIW80137.1 - 3.5e-06 27.0 0.9 0.00042 20.4 0.1 2.3 1 1 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EIW80137.1 - 7.3e-06 26.1 0.9 0.17 12.6 0.0 4.1 1 1 3 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIW80137.1 - 2.7e-05 23.7 2.7 0.053 13.1 0.0 3.2 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 EIW80137.1 - 4e-05 23.2 3.6 2.9 8.0 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EIW80137.1 - 9.7e-05 22.1 0.2 0.011 15.5 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.1 EIW80137.1 - 0.00049 19.2 0.5 0.017 14.1 0.1 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EIW80137.1 - 0.011 15.8 0.3 0.52 10.6 0.0 3.1 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIW80137.1 - 0.02 14.6 0.2 33 4.5 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIW80137.1 - 0.031 13.8 3.1 0.91 9.2 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIW80137.1 - 0.039 14.4 1.4 14 6.4 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIW80137.1 - 0.07 13.0 0.2 28 4.6 0.0 3.0 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat DUF3484 PF11983.3 EIW80137.1 - 0.27 12.0 2.4 1.8 9.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3484) TPR_12 PF13424.1 EIW80137.1 - 0.43 10.5 0.1 0.43 10.5 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.1 EIW80137.1 - 0.6 10.2 2.7 12 6.0 0.1 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat FGE-sulfatase PF03781.11 EIW80138.1 - 4e-19 68.9 1.5 1.9e-08 34.0 0.2 2.1 2 0 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EIW80138.1 - 3.1e-08 34.0 2.8 6.8e-08 32.8 2.0 1.6 1 0 0 1 1 1 1 DinB superfamily DUF2973 PF11189.3 EIW80140.1 - 2.2 8.0 4.6 12 5.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2973) DUF805 PF05656.9 EIW80140.1 - 5.9 6.7 9.6 1.3 8.9 3.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF805) Ceramidase_alk PF04734.8 EIW80141.1 - 2.9e-259 861.5 1.4 3.3e-259 861.3 1.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase Tape_meas_lam_C PF09718.5 EIW80142.1 - 0.071 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) TerB-N PF13208.1 EIW80143.1 - 0.074 12.4 0.4 0.12 11.7 0.3 1.3 1 0 0 1 1 1 0 TerB-N NADHdh-2_N PF12155.3 EIW80143.1 - 0.28 11.3 4.1 0.34 11.1 0.3 2.3 2 0 0 2 2 2 0 NADH dehydrogenase subunit 2 N-terminal DUF4212 PF13937.1 EIW80143.1 - 0.4 10.7 3.4 0.61 10.1 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4212) F-box PF00646.28 EIW80145.1 - 0.00014 21.4 0.5 0.00056 19.5 0.0 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EIW80145.1 - 0.00027 20.6 1.2 0.00065 19.3 0.1 2.3 2 0 0 2 2 2 1 F-box-like Exo_endo_phos PF03372.18 EIW80146.1 - 4.4e-11 43.2 0.0 6.3e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family F-box PF00646.28 EIW80148.1 - 0.0012 18.4 0.5 0.016 14.8 0.1 2.6 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EIW80148.1 - 0.11 12.2 2.7 0.16 11.7 0.3 2.3 2 0 0 2 2 2 0 F-box-like DEAD PF00270.24 EIW80150.1 - 4.5e-14 52.2 0.0 9.8e-14 51.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW80150.1 - 2.4e-10 40.1 0.0 1.5e-09 37.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DLH PF01738.13 EIW80151.1 - 4.8e-14 52.1 0.0 1.3e-13 50.7 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EIW80151.1 - 0.00029 20.6 0.0 0.00046 19.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW80151.1 - 0.024 14.5 0.0 3.3 7.5 0.0 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family RRM_6 PF14259.1 EIW80152.1 - 4.3e-07 29.8 0.0 7.4e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIW80152.1 - 0.00034 20.1 0.0 0.00075 19.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-alpha PF00503.15 EIW80154.1 - 1.4e-121 405.8 3.4 1.8e-121 405.5 2.4 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIW80154.1 - 6.9e-15 54.7 0.2 2.7e-09 36.4 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW80154.1 - 0.00014 21.0 1.4 0.0062 15.6 1.0 2.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EIW80154.1 - 0.0068 16.8 0.1 0.72 10.3 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EIW80154.1 - 0.021 14.2 0.0 3.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EIW80154.1 - 0.043 13.3 0.0 0.089 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain HEAT PF02985.17 EIW80155.1 - 1.5e-19 68.2 7.2 4.6e-05 23.1 0.0 8.8 8 0 0 8 8 8 5 HEAT repeat HEAT_EZ PF13513.1 EIW80155.1 - 1.5e-14 53.9 15.2 1.9e-05 24.9 0.0 10.1 9 2 1 10 10 10 2 HEAT-like repeat HEAT_2 PF13646.1 EIW80155.1 - 1.7e-12 47.4 10.9 3e-06 27.4 0.1 6.4 3 1 3 6 6 6 4 HEAT repeats Vac14_Fab1_bd PF12755.2 EIW80155.1 - 4.5e-10 39.7 0.4 2e-05 24.8 0.0 4.6 4 1 2 6 6 5 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 EIW80155.1 - 9.1e-08 31.9 1.3 7.2e-05 22.5 0.0 5.2 5 1 2 7 7 7 1 rRNA processing/ribosome biogenesis Adaptin_N PF01602.15 EIW80155.1 - 6.5e-05 21.4 0.2 0.0053 15.1 0.0 2.7 2 0 0 2 2 2 1 Adaptin N terminal region MMS19_C PF12460.3 EIW80155.1 - 0.00075 18.3 6.1 1.2 7.8 0.0 4.3 3 1 0 4 4 4 1 RNAPII transcription regulator C-terminal Cnd1 PF12717.2 EIW80155.1 - 0.0009 19.1 0.0 0.68 9.7 0.0 3.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Malate_DH PF12434.3 EIW80155.1 - 0.0097 15.5 0.1 0.32 10.7 0.1 2.8 2 0 0 2 2 2 1 Malate dehydrogenase enzyme FANCI_S2 PF14676.1 EIW80155.1 - 0.044 13.6 0.2 0.26 11.1 0.1 2.2 2 0 0 2 2 2 0 FANCI solenoid 2 DNA_pol_A_exo1 PF01612.15 EIW80155.1 - 0.058 12.8 0.1 0.16 11.4 0.0 1.7 1 0 0 1 1 1 0 3'-5' exonuclease DUF4042 PF13251.1 EIW80155.1 - 0.2 11.0 1.5 3.6 7.0 0.0 3.6 4 1 1 5 5 5 0 Domain of unknown function (DUF4042) DLH PF01738.13 EIW80156.1 - 2.1e-28 99.0 0.3 2.5e-28 98.8 0.2 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EIW80156.1 - 7.1e-10 38.8 0.0 1e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW80156.1 - 2.1e-06 27.8 0.5 0.046 13.5 0.2 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EIW80156.1 - 0.0028 17.1 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EIW80156.1 - 0.053 12.7 0.0 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family F-box-like PF12937.2 EIW80157.1 - 0.00025 20.7 0.1 0.00025 20.7 0.1 2.3 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EIW80157.1 - 0.00044 19.8 2.0 0.00074 19.1 0.0 2.3 2 0 0 2 2 2 1 F-box domain DUF566 PF04484.7 EIW80158.1 - 9.7 5.5 10.3 11 5.3 7.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) CFEM PF05730.6 EIW80159.1 - 4e-10 39.3 16.1 5.5e-10 38.9 11.2 1.2 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.15 EIW80159.1 - 0.51 10.3 4.2 0.28 11.2 1.4 1.7 1 1 0 1 1 1 0 Gamma-thionin family F-box PF00646.28 EIW80161.1 - 0.00092 18.8 0.6 0.00092 18.8 0.4 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EIW80161.1 - 0.002 17.8 3.9 0.0022 17.6 0.3 2.6 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 EIW80161.1 - 0.075 12.7 0.4 0.14 11.8 0.3 1.4 1 0 0 1 1 1 0 F-box-like domain Lactamase_B PF00753.22 EIW80162.1 - 3.8e-07 29.9 5.8 6.4e-07 29.2 4.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EIW80162.1 - 0.00012 21.7 0.5 0.00017 21.2 0.4 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EIW80162.1 - 0.01 15.5 0.2 0.016 14.9 0.1 1.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain DUF1479 PF07350.7 EIW80163.1 - 6.3e-141 469.6 0.0 7.4e-141 469.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Rapsyn_N PF10579.4 EIW80163.1 - 0.1 12.3 0.1 0.47 10.2 0.0 2.1 2 0 0 2 2 2 0 Rapsyn N-terminal myristoylation and linker region CTP-dep_RFKase PF01982.11 EIW80163.1 - 0.11 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF120 MFS_1 PF07690.11 EIW80164.1 - 1.5e-47 162.0 53.7 3.3e-46 157.6 37.8 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIW80164.1 - 4.3e-16 58.2 29.3 6.1e-16 57.7 20.3 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIW80164.1 - 5.2e-11 41.7 8.4 5.2e-11 41.7 5.8 3.6 2 1 1 3 3 3 2 Sugar (and other) transporter COesterase PF00135.23 EIW80165.1 - 1.5e-80 271.4 3.8 5.9e-80 269.4 2.6 1.7 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EIW80165.1 - 1.7e-05 24.1 0.0 2.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EIW80165.1 - 2.5e-05 23.9 0.5 7.8e-05 22.3 0.4 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW80165.1 - 0.012 15.3 0.1 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1479 PF07350.7 EIW80166.1 - 6.3e-129 430.0 0.0 7.3e-129 429.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) MFS_1 PF07690.11 EIW80168.1 - 3.4e-21 75.3 30.7 5e-21 74.7 20.3 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Lactamase_B PF00753.22 EIW80169.1 - 1.1e-13 51.2 7.2 2.2e-13 50.2 5.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EIW80169.1 - 6.1e-06 25.9 0.6 8.6e-06 25.4 0.4 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EIW80169.1 - 0.029 14.0 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIW80170.1 - 5.8e-09 35.8 3.6 7.4e-08 32.2 2.5 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EIW80170.1 - 6.5e-05 22.5 0.3 7.3e-05 22.3 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EIW80170.1 - 0.074 12.7 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain DUF2470 PF10615.4 EIW80171.1 - 5.1e-15 55.4 0.0 8.2e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.1 EIW80171.1 - 1.1e-07 31.6 0.8 2.4e-07 30.5 0.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4499) Dynamin_N PF00350.18 EIW80172.1 - 1.3e-28 99.8 0.0 2.5e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EIW80172.1 - 1.1e-15 57.1 0.0 9e-12 44.3 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 EIW80172.1 - 1.3e-11 44.2 0.9 3.6e-11 42.8 0.3 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EIW80172.1 - 0.00019 21.3 0.0 0.0016 18.4 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIW80172.1 - 0.009 16.5 0.1 0.13 12.7 0.0 2.6 3 0 0 3 3 3 1 Miro-like protein ABC_tran PF00005.22 EIW80172.1 - 0.11 12.7 0.0 0.23 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter MobB PF03205.9 EIW80172.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EIW80172.1 - 0.24 11.3 2.6 30 4.5 0.4 3.2 2 1 0 2 2 2 0 AAA ATPase domain CTK3 PF12243.3 EIW80173.1 - 9.5e-40 135.4 0.0 2.7e-38 130.7 0.0 2.2 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EIW80173.1 - 8.1e-14 51.4 14.5 1.1e-12 47.7 10.0 2.2 1 1 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus Glyco_hydro_18 PF00704.23 EIW80174.1 - 6e-20 71.9 3.7 1.7e-19 70.5 0.7 1.8 1 1 1 2 2 2 1 Glycosyl hydrolases family 18 DUF1126 PF06565.7 EIW80174.1 - 0.17 11.3 1.0 0.31 10.5 0.7 1.4 1 0 0 1 1 1 0 Repeat of unknown function (DUF1126) Lactonase PF10282.4 EIW80175.1 - 7.4e-42 143.6 0.0 8.3e-42 143.4 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF1459 PF07312.6 EIW80175.1 - 0.12 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1459) F-box PF00646.28 EIW80176.1 - 0.00032 20.2 0.1 0.00075 19.0 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW80176.1 - 0.059 13.1 0.2 0.19 11.4 0.1 1.8 1 0 0 1 1 1 0 F-box-like Lactamase_B PF00753.22 EIW80177.1 - 2.3e-10 40.4 5.1 3.5e-10 39.8 3.5 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EIW80177.1 - 2.5e-07 30.4 0.8 7.4e-07 28.9 0.8 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EIW80177.1 - 0.027 14.1 0.1 0.043 13.5 0.1 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Lactonase PF10282.4 EIW80179.1 - 2.2e-48 165.1 0.0 2.5e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller His_Phos_2 PF00328.17 EIW80180.1 - 0.00047 19.5 0.0 0.0016 17.8 0.0 1.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF4160 PF13711.1 EIW80180.1 - 0.0064 16.3 0.1 0.034 14.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4160) Abhydrolase_6 PF12697.2 EIW80181.1 - 2.9e-27 96.0 0.8 3.7e-27 95.6 0.5 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW80181.1 - 9.4e-12 44.9 0.0 1.4e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW80181.1 - 1.2e-11 44.6 0.0 5.5e-10 39.1 0.0 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EIW80181.1 - 4.3e-05 23.2 0.0 8.4e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EIW80181.1 - 0.018 14.3 0.0 0.028 13.6 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.3 EIW80181.1 - 0.079 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase DUF900 PF05990.7 EIW80181.1 - 0.098 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Cellulase PF00150.13 EIW80182.1 - 0.0019 17.4 0.0 0.0043 16.3 0.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ASFV_J13L PF05568.6 EIW80182.1 - 0.05 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF4366 PF14283.1 EIW80182.1 - 0.16 11.3 0.0 0.26 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) TEA PF01285.13 EIW80183.1 - 8.9e-14 51.4 0.0 1.2e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 TEA/ATTS domain family Myb_DNA-binding PF00249.26 EIW80183.1 - 0.08 13.0 0.1 0.21 11.6 0.0 1.8 2 0 0 2 2 2 0 Myb-like DNA-binding domain AAA_12 PF13087.1 EIW80184.1 - 7.8e-52 175.5 0.0 1.2e-51 175.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Dna2 PF08696.6 EIW80184.1 - 2.4e-45 154.4 0.0 4.6e-45 153.5 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_11 PF13086.1 EIW80184.1 - 3.7e-18 65.9 0.0 7.1e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain PDDEXK_1 PF12705.2 EIW80184.1 - 5.5e-10 39.0 0.0 1.5e-09 37.6 0.0 1.7 2 0 0 2 2 1 1 PD-(D/E)XK nuclease superfamily AAA_30 PF13604.1 EIW80184.1 - 3.1e-09 36.7 0.3 8.3e-09 35.2 0.1 1.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIW80184.1 - 5.5e-09 35.6 0.3 1.5e-08 34.2 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EIW80184.1 - 0.00078 19.4 0.0 0.0024 17.9 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EIW80184.1 - 0.00084 18.8 0.3 0.002 17.5 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain MobB PF03205.9 EIW80184.1 - 0.0016 18.1 0.2 0.0049 16.5 0.1 1.8 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 EIW80184.1 - 0.0065 15.9 0.2 0.015 14.7 0.2 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain Helicase_RecD PF05127.9 EIW80184.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Helicase UvrD-helicase PF00580.16 EIW80184.1 - 0.015 14.5 0.1 0.025 13.8 0.1 1.3 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_25 PF13481.1 EIW80184.1 - 0.015 14.6 0.0 0.047 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EIW80184.1 - 0.024 14.5 0.0 0.11 12.4 0.0 2.1 3 0 0 3 3 1 0 AAA domain ArgK PF03308.11 EIW80184.1 - 0.049 12.4 0.1 0.095 11.4 0.0 1.4 1 0 0 1 1 1 0 ArgK protein CbiA PF01656.18 EIW80184.1 - 0.049 13.0 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA PF00004.24 EIW80184.1 - 0.056 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EIW80184.1 - 0.095 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_5 PF07728.9 EIW80184.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Miro PF08477.8 EIW80184.1 - 0.13 12.7 0.0 0.28 11.6 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 EIW80184.1 - 0.13 12.2 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase NTPase_1 PF03266.10 EIW80184.1 - 0.17 11.5 0.2 0.35 10.5 0.2 1.4 1 0 0 1 1 1 0 NTPase DUF2075 PF09848.4 EIW80184.1 - 0.19 10.6 0.0 0.37 9.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) O-FucT PF10250.4 EIW80185.1 - 4.2e-08 32.6 0.0 0.0006 19.0 0.0 2.3 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase DUF2470 PF10615.4 EIW80186.1 - 8.8e-13 48.3 0.0 1.6e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) DUF4499 PF14934.1 EIW80186.1 - 5.4e-07 29.4 0.4 1.2e-06 28.4 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4499) Aldo_ket_red PF00248.16 EIW80187.1 - 9.1e-62 208.4 0.0 1.1e-61 208.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family COesterase PF00135.23 EIW80188.1 - 1.8e-71 241.4 0.0 3.3e-71 240.6 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW80188.1 - 8.1e-07 28.8 0.8 3e-06 26.9 0.5 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIW80188.1 - 0.00026 20.2 0.1 0.0006 19.1 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family F-box-like PF12937.2 EIW80190.1 - 4.6e-05 23.0 1.0 0.00016 21.3 0.7 2.0 1 0 0 1 1 1 1 F-box-like COesterase PF00135.23 EIW80191.1 - 2.4e-70 237.7 0.0 3.8e-70 237.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW80191.1 - 1.4e-07 31.3 1.5 5.8e-07 29.3 1.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIW80191.1 - 0.0038 16.4 0.2 0.0076 15.4 0.2 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIW80191.1 - 0.048 13.4 0.5 0.089 12.5 0.3 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family CFEM PF05730.6 EIW80192.1 - 4e-09 36.1 12.5 6.3e-09 35.5 8.7 1.3 1 0 0 1 1 1 1 CFEM domain IalB PF06776.7 EIW80192.1 - 0.0083 15.9 1.1 0.011 15.6 0.4 1.4 1 1 0 1 1 1 1 Invasion associated locus B (IalB) protein Gamma-thionin PF00304.15 EIW80192.1 - 0.043 13.8 0.5 0.084 12.9 0.4 1.4 1 0 0 1 1 1 0 Gamma-thionin family Bestrophin PF01062.16 EIW80194.1 - 2.7e-48 164.4 0.0 5.9e-28 97.6 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF2244 PF10003.4 EIW80194.1 - 0.044 13.1 0.3 0.14 11.5 0.2 1.9 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF4229 PF14012.1 EIW80194.1 - 0.37 10.7 3.3 0.94 9.4 2.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF2838 PF10998.3 EIW80195.1 - 0.3 11.0 2.6 0.71 9.7 1.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2838) DUF1180 PF06679.7 EIW80196.1 - 0.027 14.3 0.0 0.027 14.3 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) Presenilin PF01080.12 EIW80196.1 - 0.68 8.6 2.5 3.6 6.3 0.7 2.0 2 0 0 2 2 2 0 Presenilin HEAT_2 PF13646.1 EIW80197.1 - 2.8e-28 98.0 44.1 3.1e-05 24.1 0.0 15.2 11 3 6 17 17 16 9 HEAT repeats HEAT_EZ PF13513.1 EIW80197.1 - 2.5e-25 88.2 38.5 0.00011 22.5 0.0 18.9 17 5 4 21 21 19 8 HEAT-like repeat HEAT PF02985.17 EIW80197.1 - 1.4e-22 77.7 32.2 0.2 11.8 0.1 19.1 23 0 0 23 23 20 5 HEAT repeat DUF3554 PF12074.3 EIW80197.1 - 5.2e-19 68.8 0.0 1.2e-14 54.4 0.0 5.3 4 2 0 4 4 4 1 Domain of unknown function (DUF3554) CLASP_N PF12348.3 EIW80197.1 - 5.1e-11 42.3 0.0 0.0015 17.9 0.0 6.4 4 2 1 6 6 6 2 CLASP N terminal Vac14_Fab1_bd PF12755.2 EIW80197.1 - 2e-06 28.0 0.0 6.9 7.1 0.0 6.0 5 1 1 6 6 6 1 Vacuolar 14 Fab1-binding region Ecm29 PF13001.2 EIW80197.1 - 4.4e-06 25.4 0.6 0.28 9.6 0.0 5.3 6 0 0 6 6 6 2 Proteasome stabiliser Adaptin_N PF01602.15 EIW80197.1 - 9.7e-05 20.8 2.0 0.61 8.3 1.9 4.9 4 2 0 4 4 4 1 Adaptin N terminal region Cnd1 PF12717.2 EIW80197.1 - 0.0026 17.6 0.0 9.7 5.9 0.0 6.0 6 2 2 8 8 7 1 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.4 EIW80197.1 - 0.0032 17.3 2.5 92 2.8 0.0 6.2 5 2 1 6 6 6 0 Parkin co-regulated protein DUF760 PF05542.6 EIW80197.1 - 0.14 12.3 1.7 7.3 6.8 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF760) TLE_N PF03920.10 EIW80197.1 - 0.38 10.5 0.2 3.9 7.2 0.0 2.6 3 0 0 3 3 3 0 Groucho/TLE N-terminal Q-rich domain Cohesin_HEAT PF12765.2 EIW80197.1 - 1.6 8.8 9.1 3.2 7.8 0.6 5.5 6 0 0 6 6 6 0 HEAT repeat associated with sister chromatid cohesion Chondroitinas_B PF14592.1 EIW80197.1 - 1.7 7.3 0.0 2.7 6.7 0.0 1.1 1 0 0 1 1 1 0 Chondroitinase B polyprenyl_synt PF00348.12 EIW80198.1 - 1.2e-50 171.7 0.0 3.2e-50 170.3 0.0 1.6 1 1 0 1 1 1 1 Polyprenyl synthetase DRIM PF07539.7 EIW80199.1 - 2e-32 111.5 0.0 7.5e-32 109.6 0.0 2.1 1 0 0 1 1 1 1 Down-regulated in metastasis MMS19_N PF14500.1 EIW80199.1 - 0.00011 21.5 0.4 0.0033 16.7 0.1 2.9 2 1 1 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT PF02985.17 EIW80199.1 - 0.0017 18.2 8.3 6.3 7.1 0.0 8.1 9 0 0 9 9 9 1 HEAT repeat Polysacc_lyase PF14099.1 EIW80200.1 - 0.059 13.0 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Polysaccharide lyase Dynamin_N PF00350.18 EIW80201.1 - 2.9e-28 98.7 0.0 6.6e-28 97.6 0.0 1.6 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EIW80201.1 - 9.1e-22 77.1 0.0 1.8e-14 53.2 0.0 2.2 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 EIW80201.1 - 1.8e-10 40.5 0.1 4.9e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EIW80201.1 - 0.00019 21.3 0.0 0.0037 17.2 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase RNA_pol_Rpb5_C PF01191.14 EIW80201.1 - 0.011 15.2 0.8 1.9 8.1 0.1 2.7 2 0 0 2 2 2 0 RNA polymerase Rpb5, C-terminal domain Miro PF08477.8 EIW80201.1 - 0.031 14.7 0.0 0.066 13.7 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein AAA_21 PF13304.1 EIW80201.1 - 0.031 14.2 0.0 0.08 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIW80201.1 - 0.037 13.5 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EIW80201.1 - 0.04 13.8 0.5 1.6 8.6 0.0 2.9 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 EIW80201.1 - 0.044 14.0 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DUF326 PF03860.11 EIW80201.1 - 0.3 10.9 2.7 3.2 7.7 0.6 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF326) COesterase PF00135.23 EIW80202.1 - 9.1e-90 301.8 1.0 2.3e-89 300.5 0.7 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW80202.1 - 2.8e-08 33.5 0.4 1.1e-07 31.6 0.3 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIW80202.1 - 0.014 14.6 0.1 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF645 PF04875.7 EIW80202.1 - 0.078 12.6 0.0 0.38 10.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF645 HNH_2 PF13391.1 EIW80203.1 - 0.00038 20.1 1.0 0.00051 19.7 0.0 1.7 2 0 0 2 2 2 1 HNH endonuclease ACR_tran PF00873.14 EIW80205.1 - 0.00051 17.6 0.4 0.00068 17.1 0.3 1.1 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family Abhydrolase_6 PF12697.2 EIW80206.1 - 1.5e-18 67.5 0.1 1.9e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW80206.1 - 0.00013 21.7 0.0 0.00066 19.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF281 PF03436.8 EIW80208.1 - 1 9.4 5.8 5.4 7.1 4.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF281) DUF1970 PF09301.5 EIW80208.1 - 1 9.4 4.6 1.2 9.1 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) PNRC PF15365.1 EIW80209.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Proline-rich nuclear receptor coactivator NIF PF03031.13 EIW80210.1 - 8.4e-38 129.5 0.1 1.4e-37 128.8 0.1 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase NAD_binding_5 PF07994.7 EIW80213.1 - 6.2e-105 350.9 0.0 7.3e-105 350.6 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EIW80213.1 - 3.1e-45 152.6 0.0 6.7e-45 151.5 0.0 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase DPBB_1 PF03330.13 EIW80214.1 - 0.0033 17.4 0.1 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel RVT_3 PF13456.1 EIW80216.1 - 0.089 12.5 0.1 7.5 6.4 0.0 2.6 2 0 0 2 2 2 0 Reverse transcriptase-like DUF1295 PF06966.7 EIW80218.1 - 9.1e-43 146.2 2.7 1.5e-42 145.5 1.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EIW80218.1 - 0.00075 19.5 0.0 0.00075 19.5 0.0 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.11 EIW80218.1 - 0.014 15.1 0.1 0.051 13.3 0.0 1.9 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase PH PF00169.24 EIW80218.1 - 0.096 12.8 0.0 0.31 11.2 0.0 1.8 1 0 0 1 1 1 0 PH domain ICMT PF04140.9 EIW80218.1 - 0.11 12.7 0.0 0.11 12.7 0.0 1.9 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family AvrE PF11725.3 EIW80218.1 - 9.7 3.0 11.9 13 2.6 8.2 1.1 1 0 0 1 1 1 0 Pathogenicity factor DUF59 PF01883.14 EIW80220.1 - 0.031 14.2 0.1 0.089 12.7 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF59 TRAP_alpha PF03896.11 EIW80220.1 - 0.074 12.0 1.1 0.14 11.1 0.8 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PspC PF04024.7 EIW80220.1 - 0.1 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 PspC domain SOBP PF15279.1 EIW80220.1 - 0.17 12.2 10.2 0.24 11.7 7.0 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Hydrophobin PF01185.13 EIW80221.1 - 1.1e-23 83.5 12.0 1.3e-23 83.2 8.3 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Cyclase PF04199.8 EIW80222.1 - 1.3e-32 112.7 0.2 1.7e-32 112.4 0.1 1.1 1 0 0 1 1 1 1 Putative cyclase Mucin PF01456.12 EIW80224.1 - 0.2 11.4 3.5 0.094 12.4 0.2 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein Glyco_tranf_2_3 PF13641.1 EIW80225.1 - 0.015 15.1 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Clat_adaptor_s PF01217.15 EIW80226.1 - 1.5e-15 57.1 0.0 2.6e-15 56.4 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Gasdermin PF04598.7 EIW80226.1 - 0.1 11.3 0.1 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Gasdermin family Mso1_Sec1_bdg PF14475.1 EIW80226.1 - 0.14 11.5 0.0 0.64 9.4 0.0 2.1 2 0 0 2 2 2 0 Sec1-binding region of Mso1 ATG16 PF08614.6 EIW80227.1 - 0.0021 17.9 6.2 0.0021 17.9 4.3 4.0 2 1 1 3 3 3 1 Autophagy protein 16 (ATG16) DUF972 PF06156.8 EIW80227.1 - 0.0024 18.1 3.2 0.0024 18.1 2.2 4.8 2 1 3 5 5 5 1 Protein of unknown function (DUF972) AAA_13 PF13166.1 EIW80227.1 - 0.003 16.0 21.6 0.077 11.4 1.9 2.1 2 0 0 2 2 2 2 AAA domain CENP-F_leu_zip PF10473.4 EIW80227.1 - 0.0076 16.1 47.6 0.076 12.8 6.0 4.2 2 1 2 4 4 4 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec8_exocyst PF04048.9 EIW80227.1 - 0.011 15.3 7.9 0.46 10.1 0.8 2.7 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain bZIP_1 PF00170.16 EIW80227.1 - 0.012 15.6 48.9 0.12 12.3 2.4 7.2 4 3 3 7 7 7 0 bZIP transcription factor Phage_GP20 PF06810.6 EIW80227.1 - 0.013 14.9 2.9 0.013 14.9 2.0 3.8 2 1 2 4 4 4 0 Phage minor structural protein GP20 Reo_sigmaC PF04582.7 EIW80227.1 - 0.028 13.6 10.2 0.39 9.8 0.5 2.9 1 1 2 3 3 3 0 Reovirus sigma C capsid protein DivIC PF04977.10 EIW80227.1 - 0.079 12.4 0.3 0.079 12.4 0.2 6.1 4 3 2 6 6 6 0 Septum formation initiator HOOK PF05622.7 EIW80227.1 - 0.11 10.3 38.1 0.088 10.6 16.0 2.6 2 1 0 2 2 2 0 HOOK protein Spc7 PF08317.6 EIW80227.1 - 0.16 10.5 34.7 0.067 11.8 4.6 3.1 2 1 0 3 3 3 0 Spc7 kinetochore protein IncA PF04156.9 EIW80227.1 - 0.21 11.1 46.4 0.024 14.2 4.3 3.4 2 1 1 3 3 3 0 IncA protein Mod_r PF07200.8 EIW80227.1 - 0.34 10.7 37.3 0.059 13.2 3.5 3.7 2 1 1 3 3 3 0 Modifier of rudimentary (Mod(r)) protein DUF1664 PF07889.7 EIW80227.1 - 1.2 8.9 13.4 1.2 8.9 1.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TBPIP PF07106.8 EIW80227.1 - 1.8 8.1 30.2 0.028 13.9 3.3 3.8 2 1 2 4 4 4 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) RTBV_P46 PF06216.6 EIW80227.1 - 2.4 6.9 11.3 0.78 8.5 1.1 2.8 2 1 1 3 3 3 0 Rice tungro bacilliform virus P46 protein TMF_TATA_bd PF12325.3 EIW80227.1 - 3.1 7.5 46.7 2.3 7.9 4.4 4.7 2 2 2 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF904 PF06005.7 EIW80227.1 - 3.2 8.1 47.7 3.3 8.0 6.6 6.2 2 1 2 4 4 4 0 Protein of unknown function (DUF904) DUF342 PF03961.8 EIW80227.1 - 4.1 5.7 24.2 0.24 9.7 2.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF342) Bacillus_HBL PF05791.6 EIW80227.1 - 5.4 6.3 10.6 1.1 8.6 0.6 2.6 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) GAS PF13851.1 EIW80227.1 - 6.1 5.9 40.6 4.1 6.5 5.8 3.6 2 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding HAP1_N PF04849.8 EIW80227.1 - 6.3 5.6 44.9 0.31 9.9 5.8 4.5 2 1 1 3 3 3 0 HAP1 N-terminal conserved region ParB PF08775.5 EIW80227.1 - 6.9 6.9 9.7 1.3 9.3 0.8 2.7 2 1 0 2 2 2 0 ParB family DUF4279 PF14106.1 EIW80227.1 - 6.9 6.5 8.0 25 4.7 0.5 3.2 2 2 2 4 4 4 0 Domain of unknown function (DUF4279) APG6 PF04111.7 EIW80227.1 - 7 5.5 43.8 0.5 9.3 7.1 3.1 1 1 2 3 3 3 0 Autophagy protein Apg6 WD40 PF00400.27 EIW80228.1 - 4.6e-21 73.8 0.3 7.1e-06 25.7 0.1 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW80228.1 - 3.2e-08 33.3 0.3 0.027 13.9 0.1 3.7 2 1 0 2 2 2 2 PQQ-like domain eIF2A PF08662.6 EIW80228.1 - 1.5e-07 31.3 0.0 0.014 15.1 0.0 3.3 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EIW80228.1 - 2.3e-06 27.1 0.6 0.33 10.6 0.0 5.1 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat DPPIV_N PF00930.16 EIW80228.1 - 4.8e-05 22.0 0.0 0.025 13.1 0.0 3.2 2 1 2 4 4 4 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Nbas_N PF15492.1 EIW80228.1 - 0.00074 18.7 0.0 1.9 7.4 0.0 3.7 2 1 0 4 4 4 2 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 EIW80228.1 - 0.0098 13.7 0.0 0.062 11.1 0.0 2.0 2 0 0 2 2 2 1 IKI3 family PQQ PF01011.16 EIW80228.1 - 0.017 14.6 4.1 6.2 6.5 0.0 4.4 4 1 1 5 5 5 0 PQQ enzyme repeat PQQ_3 PF13570.1 EIW80228.1 - 2.3 8.5 8.7 32 4.9 0.0 4.7 4 1 1 5 5 5 0 PQQ-like domain HNH_2 PF13391.1 EIW80229.1 - 0.00036 20.2 0.1 0.00073 19.2 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease HNH_2 PF13391.1 EIW80230.1 - 0.018 14.7 0.1 0.19 11.5 0.0 2.3 2 0 0 2 2 2 0 HNH endonuclease adh_short PF00106.20 EIW80233.1 - 9.3e-27 93.9 1.0 9.4e-26 90.7 0.7 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW80233.1 - 8.1e-18 65.0 0.6 1.9e-17 63.8 0.4 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW80233.1 - 2.7e-11 43.4 0.3 4.9e-11 42.6 0.2 1.6 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EIW80233.1 - 0.00072 19.2 0.1 0.0014 18.3 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EIW80233.1 - 0.011 15.1 0.6 0.057 12.8 0.4 2.0 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pyr_redox PF00070.22 EIW80233.1 - 0.015 15.6 0.1 0.077 13.4 0.0 2.1 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DUF1776 PF08643.5 EIW80233.1 - 0.097 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.21 EIW80233.1 - 0.12 11.9 0.1 0.23 10.9 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EIW80233.1 - 0.14 12.1 0.8 0.31 11.0 0.2 1.9 2 1 0 2 2 2 0 NADH(P)-binding Pkinase PF00069.20 EIW80234.1 - 9.5e-08 31.4 0.0 1e-07 31.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain DUF1903 PF08991.5 EIW80235.1 - 1.4e-14 53.9 4.3 1.7e-14 53.6 3.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) Pet191_N PF10203.4 EIW80235.1 - 0.33 11.0 5.5 0.4 10.7 3.8 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 EIW80235.1 - 0.64 9.9 7.7 1.3 9.0 5.4 1.6 1 0 0 1 1 1 0 CHCH domain Cmc1 PF08583.5 EIW80235.1 - 3.8 7.3 7.4 1.1 9.0 1.4 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DUF4098 PF13345.1 EIW80236.1 - 0.12 12.3 0.2 0.24 11.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4098) Toxin_28 PF08115.6 EIW80236.1 - 0.93 9.2 5.2 1 9.0 0.0 2.9 3 0 0 3 3 3 0 SFI toxin family NACHT PF05729.7 EIW80237.1 - 4.3e-08 32.9 0.0 5.4e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW80237.1 - 3.5e-07 30.4 0.0 3.7e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW80237.1 - 0.00015 21.9 0.0 0.00017 21.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EIW80237.1 - 0.0002 21.4 0.0 0.00035 20.7 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.1 EIW80237.1 - 0.00049 20.9 0.1 0.00051 20.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EIW80237.1 - 0.00051 19.6 0.0 0.00066 19.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EIW80237.1 - 0.00068 19.9 0.1 0.00079 19.7 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW80237.1 - 0.0011 18.8 0.1 0.0015 18.4 0.1 1.4 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIW80237.1 - 0.0016 18.7 0.0 0.0017 18.6 0.0 1.3 1 1 0 1 1 1 1 ABC transporter APS_kinase PF01583.15 EIW80237.1 - 0.0021 17.7 0.0 0.0023 17.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase NTPase_1 PF03266.10 EIW80237.1 - 0.0035 17.0 0.0 0.0036 17.0 0.0 1.2 1 1 0 1 1 1 1 NTPase MobB PF03205.9 EIW80237.1 - 0.014 15.1 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EIW80237.1 - 0.016 14.7 0.1 0.032 13.7 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.2 EIW80237.1 - 0.019 14.4 0.0 0.021 14.3 0.0 1.2 1 1 0 1 1 1 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EIW80237.1 - 0.021 14.2 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.24 EIW80237.1 - 0.031 14.4 0.1 0.067 13.3 0.0 1.7 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.4 EIW80237.1 - 0.033 13.1 0.0 0.033 13.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.9 EIW80237.1 - 0.047 13.4 0.0 0.069 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 EIW80237.1 - 0.048 13.4 0.2 0.16 11.7 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function DUF87 Zeta_toxin PF06414.7 EIW80237.1 - 0.049 12.7 0.1 0.13 11.3 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin DUF258 PF03193.11 EIW80237.1 - 0.079 12.1 0.0 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ADK PF00406.17 EIW80237.1 - 0.086 12.7 0.1 0.35 10.7 0.1 1.8 1 1 1 2 2 2 0 Adenylate kinase SKI PF01202.17 EIW80237.1 - 0.1 12.4 0.1 0.18 11.6 0.0 1.5 2 0 0 2 2 2 0 Shikimate kinase Cytidylate_kin2 PF13189.1 EIW80237.1 - 0.12 12.2 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase-like family Abhydrolase_6 PF12697.2 EIW80238.1 - 1.1e-37 130.0 0.2 1.4e-37 129.8 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW80238.1 - 1.5e-19 70.1 0.2 2.4e-19 69.5 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW80238.1 - 1.5e-18 67.2 0.2 1.6e-16 60.5 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 EIW80238.1 - 3.8e-08 32.1 0.0 4e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Ndr family Ser_hydrolase PF06821.8 EIW80238.1 - 1.9e-05 24.3 0.5 0.00048 19.7 0.1 2.3 1 1 0 2 2 2 1 Serine hydrolase PGAP1 PF07819.8 EIW80238.1 - 4.1e-05 23.2 2.0 0.00064 19.3 1.4 2.1 1 1 0 1 1 1 1 PGAP1-like protein DUF915 PF06028.6 EIW80238.1 - 0.00039 19.5 0.0 0.058 12.4 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) DUF2305 PF10230.4 EIW80238.1 - 0.0014 18.1 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 EIW80238.1 - 0.0023 17.7 0.0 0.0054 16.5 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 EIW80238.1 - 0.0035 16.9 0.1 0.0047 16.5 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Acyl_transf_1 PF00698.16 EIW80238.1 - 0.0071 15.7 2.9 0.01 15.2 0.8 1.8 1 1 1 2 2 2 1 Acyl transferase domain DUF676 PF05057.9 EIW80238.1 - 0.013 14.7 1.7 0.061 12.6 1.2 1.9 1 1 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EIW80238.1 - 0.045 13.3 0.1 0.063 12.8 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.15 EIW80238.1 - 0.047 13.9 0.0 0.057 13.6 0.0 1.3 1 1 0 1 1 1 0 Thioesterase domain Abhydro_lipase PF04083.11 EIW80238.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Adeno_PV PF03910.8 EIW80239.1 - 0.08 12.0 3.3 0.1 11.6 2.3 1.3 1 0 0 1 1 1 0 Adenovirus minor core protein PV MIP-T3 PF10243.4 EIW80240.1 - 0.016 13.7 8.5 0.031 12.7 5.9 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 AMP-binding PF00501.23 EIW80241.1 - 2.4e-30 105.2 0.0 4.5e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EIW80241.1 - 1.5e-28 99.3 0.0 2.5e-28 98.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EIW80241.1 - 7.1e-07 29.4 0.7 0.00026 21.0 0.2 3.4 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EIW80241.1 - 3.2e-06 26.7 0.0 7.9e-06 25.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EIW80241.1 - 0.00019 21.5 0.0 0.00066 19.9 0.0 2.0 1 1 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EIW80241.1 - 0.002 18.0 1.9 0.017 15.0 1.3 2.7 1 1 0 1 1 1 1 short chain dehydrogenase DAP10 PF07213.6 EIW80242.1 - 0.0033 17.1 0.2 0.0033 17.1 0.1 2.3 2 0 0 2 2 2 1 DAP10 membrane protein Herpes_gE PF02480.11 EIW80242.1 - 0.0062 14.8 0.1 0.014 13.7 0.1 1.5 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 EIW80242.1 - 0.14 11.8 0.3 0.43 10.2 0.2 1.8 1 0 0 1 1 1 0 TMEM154 protein family EphA2_TM PF14575.1 EIW80242.1 - 0.15 12.5 0.0 0.29 11.5 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Serglycin PF04360.7 EIW80242.1 - 0.32 10.7 26.3 0.21 11.3 3.0 3.6 3 0 0 3 3 3 0 Serglycin Adeno_E3_CR2 PF02439.10 EIW80242.1 - 3.3 7.3 5.1 6.9 6.3 3.5 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Sec66 PF09802.4 EIW80243.1 - 0.026 13.9 5.7 0.51 9.6 0.2 2.1 2 0 0 2 2 2 0 Preprotein translocase subunit Sec66 bZIP_2 PF07716.10 EIW80243.1 - 0.088 12.6 0.5 0.088 12.6 0.4 4.8 5 0 0 5 5 5 0 Basic region leucine zipper GAGA_bind PF06217.7 EIW80243.1 - 0.25 11.2 4.2 0.29 11.0 2.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Fzo_mitofusin PF04799.8 EIW80243.1 - 0.4 10.0 10.8 0.11 11.8 1.9 2.2 2 0 0 2 2 2 0 fzo-like conserved region Band_7 PF01145.20 EIW80243.1 - 0.74 9.6 4.3 1.2 9.0 3.0 1.6 1 1 0 1 1 1 0 SPFH domain / Band 7 family bZIP_1 PF00170.16 EIW80243.1 - 0.9 9.5 15.7 0.67 9.9 1.1 4.2 3 2 1 4 4 4 0 bZIP transcription factor Mnd1 PF03962.10 EIW80243.1 - 2.2 7.9 11.0 2.2 7.8 4.6 2.3 1 1 1 2 2 2 0 Mnd1 family DivIC PF04977.10 EIW80243.1 - 2.2 7.8 14.4 1.4 8.4 0.1 3.4 4 1 1 5 5 5 0 Septum formation initiator DUF972 PF06156.8 EIW80243.1 - 3.3 8.0 16.4 7.5 6.9 4.7 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Rho_Binding PF08912.6 EIW80244.1 - 0.0084 16.3 2.2 0.0084 16.3 1.5 2.6 2 1 0 2 2 2 1 Rho Binding Glyoxalase PF00903.20 EIW80244.1 - 0.08 12.9 1.6 0.12 12.3 1.1 1.5 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF2937 PF11157.3 EIW80244.1 - 0.63 9.3 4.7 0.43 9.8 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) HALZ PF02183.13 EIW80244.1 - 1.4 8.7 5.3 6.2 6.6 0.1 3.2 2 1 1 4 4 4 0 Homeobox associated leucine zipper DUF2630 PF10944.3 EIW80244.1 - 1.7 8.7 13.6 3.3 7.8 3.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2630) DUF724 PF05266.9 EIW80244.1 - 2 8.0 13.1 1.1 8.8 6.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF972 PF06156.8 EIW80244.1 - 2.7 8.3 16.0 0.33 11.3 2.6 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) MerR-DNA-bind PF09278.6 EIW80244.1 - 4.5 7.7 9.6 3.9 7.9 0.9 2.8 1 1 1 2 2 2 0 MerR, DNA binding DUF2011 PF09428.5 EIW80246.1 - 0.016 15.0 0.2 0.018 14.9 0.1 1.1 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2011) BLVR PF06375.6 EIW80246.1 - 0.06 13.1 1.2 0.075 12.8 0.8 1.2 1 0 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) DDHD PF02862.12 EIW80246.1 - 0.13 12.0 2.0 0.15 11.8 1.4 1.1 1 0 0 1 1 1 0 DDHD domain Apt1 PF10351.4 EIW80246.1 - 0.18 10.6 4.6 0.21 10.4 3.2 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain PBP1_TM PF14812.1 EIW80246.1 - 0.28 11.5 3.5 0.25 11.6 0.9 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_16 PF13191.1 EIW80247.1 - 7.7e-08 32.5 0.2 8.9e-08 32.3 0.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EIW80247.1 - 8.2e-06 25.5 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EIW80247.1 - 2e-05 24.7 0.0 3.3e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EIW80247.1 - 3.6e-05 23.4 0.0 5.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.17 EIW80247.1 - 0.00018 21.6 0.0 0.00028 21.0 0.0 1.3 1 0 0 1 1 1 1 RNA helicase ABC_tran PF00005.22 EIW80247.1 - 0.0043 17.3 0.0 0.0049 17.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter DUF2075 PF09848.4 EIW80247.1 - 0.0059 15.6 0.0 0.007 15.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Torsin PF06309.6 EIW80247.1 - 0.0061 16.4 0.0 0.01 15.7 0.0 1.4 1 1 0 1 1 1 1 Torsin UPF0079 PF02367.12 EIW80247.1 - 0.0078 15.8 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 EIW80247.1 - 0.019 13.8 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.21 EIW80247.1 - 0.02 14.3 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.1 EIW80247.1 - 0.022 14.2 0.0 0.045 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.13 EIW80247.1 - 0.023 14.2 0.0 0.029 13.9 0.0 1.4 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EIW80247.1 - 0.026 14.8 0.0 0.031 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIW80247.1 - 0.027 13.5 0.0 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin TrwB_AAD_bind PF10412.4 EIW80247.1 - 0.051 12.2 0.1 0.071 11.7 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain T2SE PF00437.15 EIW80247.1 - 0.056 12.3 0.1 0.077 11.8 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF258 PF03193.11 EIW80247.1 - 0.061 12.5 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EIW80247.1 - 0.069 12.8 0.0 0.07 12.8 0.0 1.1 1 0 0 1 1 1 0 Archaeal ATPase Cytidylate_kin2 PF13189.1 EIW80247.1 - 0.069 13.0 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_10 PF12846.2 EIW80247.1 - 0.07 12.5 0.0 0.088 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Sigma54_activ_2 PF14532.1 EIW80247.1 - 0.072 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.8 EIW80247.1 - 0.083 11.5 0.0 0.097 11.3 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus PIF1 PF05970.9 EIW80247.1 - 0.084 11.8 0.0 0.11 11.3 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase CbiA PF01656.18 EIW80247.1 - 0.086 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.10 EIW80247.1 - 0.12 12.1 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 NTPase PhoH PF02562.11 EIW80247.1 - 0.12 11.5 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.12 EIW80247.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein DAP3 PF10236.4 EIW80247.1 - 0.12 11.2 0.0 0.17 10.8 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 CPT PF07931.7 EIW80247.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.1 EIW80247.1 - 0.14 13.0 0.0 0.15 12.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EIW80247.1 - 0.14 11.2 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 KaiC TauD PF02668.11 EIW80249.1 - 6.4e-52 176.7 0.2 7.8e-52 176.4 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family HALZ PF02183.13 EIW80250.1 - 1.5 8.5 57.3 0.055 13.1 1.4 9.7 7 2 3 10 10 10 0 Homeobox associated leucine zipper Alpha_L_fucos PF01120.12 EIW80251.1 - 8.9e-80 268.1 6.2 1.2e-79 267.7 4.3 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase GHL6 PF14871.1 EIW80251.1 - 0.062 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 Phage_Coat_B PF05356.6 EIW80251.1 - 0.092 12.4 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Phage Coat protein B Dioxygenase_C PF00775.16 EIW80252.1 - 2e-52 177.1 0.0 3.1e-52 176.5 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EIW80252.1 - 2.9e-09 36.7 0.0 5.1e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EIW80252.1 - 1.4e-05 25.0 0.0 9.8e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.4 EIW80252.1 - 0.04 13.9 0.0 0.071 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) F-box-like PF12937.2 EIW80253.1 - 8.8e-11 41.3 0.7 2e-10 40.2 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW80253.1 - 0.066 12.8 0.2 0.31 10.7 0.1 2.1 1 1 0 1 1 1 0 F-box domain F-box-like PF12937.2 EIW80254.1 - 7.3e-10 38.4 3.2 9.9e-10 38.0 0.9 2.3 2 0 0 2 2 2 1 F-box-like CobT PF06213.7 EIW80254.1 - 7.1 5.6 16.6 11 5.1 11.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Alpha_L_fucos PF01120.12 EIW80256.1 - 2.4e-77 260.2 7.1 3.4e-77 259.7 4.9 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Ubiquitin_2 PF14560.1 EIW80258.1 - 0.03 14.5 0.0 0.062 13.5 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain AAA_16 PF13191.1 EIW80259.1 - 1e-09 38.6 0.1 1.5e-09 38.1 0.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EIW80259.1 - 2.5e-09 37.0 0.0 4e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EIW80259.1 - 1.2e-05 25.4 0.0 4.4e-05 23.6 0.0 1.9 1 1 1 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EIW80259.1 - 8.5e-05 22.3 0.0 0.00011 22.0 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase RNA_helicase PF00910.17 EIW80259.1 - 0.00035 20.7 0.0 0.00068 19.7 0.0 1.5 1 0 0 1 1 1 1 RNA helicase APS_kinase PF01583.15 EIW80259.1 - 0.00077 19.1 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PRK PF00485.13 EIW80259.1 - 0.0008 19.0 0.0 0.0013 18.3 0.0 1.5 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family MobB PF03205.9 EIW80259.1 - 0.0012 18.5 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EIW80259.1 - 0.0015 18.3 0.0 0.0023 17.6 0.0 1.4 1 1 0 1 1 1 1 NTPase AAA_17 PF13207.1 EIW80259.1 - 0.0022 18.7 0.0 0.0043 17.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIW80259.1 - 0.0039 17.5 0.0 0.0048 17.1 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_33 PF13671.1 EIW80259.1 - 0.0058 16.5 0.1 0.012 15.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EIW80259.1 - 0.0085 15.6 0.1 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EIW80259.1 - 0.01 16.1 0.0 0.015 15.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIW80259.1 - 0.013 14.5 0.0 0.027 13.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.2 EIW80259.1 - 0.019 14.4 0.0 0.024 14.1 0.0 1.3 1 1 0 1 1 1 0 AAA-like domain DUF2075 PF09848.4 EIW80259.1 - 0.029 13.3 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) ArgK PF03308.11 EIW80259.1 - 0.038 12.7 0.0 0.06 12.1 0.0 1.2 1 0 0 1 1 1 0 ArgK protein KaiC PF06745.8 EIW80259.1 - 0.042 12.9 0.0 0.24 10.5 0.0 1.9 2 0 0 2 2 2 0 KaiC YbaB_DNA_bd PF02575.11 EIW80259.1 - 0.047 13.5 0.1 0.083 12.7 0.1 1.4 1 0 0 1 1 1 0 YbaB/EbfC DNA-binding family DUF258 PF03193.11 EIW80259.1 - 0.058 12.5 0.0 0.075 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EIW80259.1 - 0.067 12.6 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EIW80260.1 - 5e-10 39.6 0.0 6e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EIW80260.1 - 2.4e-05 24.0 0.0 3.3e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EIW80260.1 - 0.00014 22.0 0.0 0.00017 21.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EIW80260.1 - 0.00018 21.1 0.0 0.00026 20.6 0.0 1.6 1 1 0 1 1 1 1 Adenylylsulphate kinase PRK PF00485.13 EIW80260.1 - 0.00063 19.3 0.0 0.00072 19.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.17 EIW80260.1 - 0.0007 19.7 0.0 0.0011 19.1 0.0 1.3 1 0 0 1 1 1 1 RNA helicase Arch_ATPase PF01637.13 EIW80260.1 - 0.00089 19.0 0.0 0.00091 18.9 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase Zeta_toxin PF06414.7 EIW80260.1 - 0.0016 17.6 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_29 PF13555.1 EIW80260.1 - 0.0018 17.7 0.1 0.003 17.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NTPase_1 PF03266.10 EIW80260.1 - 0.0033 17.1 0.0 0.0045 16.7 0.0 1.3 1 0 0 1 1 1 1 NTPase MobB PF03205.9 EIW80260.1 - 0.0034 17.1 0.0 0.0053 16.4 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EIW80260.1 - 0.0038 17.5 0.0 0.0063 16.8 0.0 1.3 1 1 0 1 1 1 1 ABC transporter AAA_18 PF13238.1 EIW80260.1 - 0.008 16.4 0.0 0.0093 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW80260.1 - 0.012 16.4 0.0 0.015 16.1 0.0 1.3 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EIW80260.1 - 0.017 14.5 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF2075 PF09848.4 EIW80260.1 - 0.024 13.5 0.0 0.024 13.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.1 EIW80260.1 - 0.032 14.1 0.0 0.037 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain Torsin PF06309.6 EIW80260.1 - 0.039 13.8 0.0 0.059 13.2 0.0 1.4 1 1 0 1 1 1 0 Torsin T2SE PF00437.15 EIW80260.1 - 0.044 12.6 0.0 0.061 12.2 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 EIW80260.1 - 0.08 12.3 0.0 0.093 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ArgK PF03308.11 EIW80260.1 - 0.09 11.5 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 ArgK protein DUF258 PF03193.11 EIW80260.1 - 0.095 11.8 0.0 0.095 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF258 KAP_NTPase PF07693.9 EIW80260.1 - 0.13 11.2 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain SMC_N PF02463.14 EIW80260.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Cyclase PF04199.8 EIW80265.1 - 2.3e-35 121.7 0.0 3e-35 121.4 0.0 1.1 1 0 0 1 1 1 1 Putative cyclase GST_N_2 PF13409.1 EIW80266.1 - 3.7e-20 71.7 0.0 1.9e-19 69.4 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW80266.1 - 3.8e-17 61.9 0.0 8.4e-17 60.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW80266.1 - 8e-10 38.5 0.0 1.4e-09 37.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW80266.1 - 1.4e-06 28.6 0.0 2.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIW80266.1 - 7e-06 26.1 0.1 0.18 12.0 0.0 2.7 3 0 0 3 3 3 2 Glutathione S-transferase, N-terminal domain DUF4646 PF15496.1 EIW80267.1 - 5.1e-21 74.9 0.0 1.2e-20 73.8 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4646) zf-CHY PF05495.7 EIW80268.1 - 1.6e-16 60.1 18.1 2e-16 59.8 12.5 1.1 1 0 0 1 1 1 1 CHY zinc finger ArfGap PF01412.13 EIW80268.1 - 0.0032 17.2 0.6 0.0032 17.2 0.4 1.5 1 1 0 1 1 1 1 Putative GTPase activating protein for Arf zf-FPG_IleRS PF06827.9 EIW80268.1 - 0.0039 16.7 0.8 0.014 15.0 0.5 1.9 1 1 0 1 1 1 1 Zinc finger found in FPG and IleRS Zn-ribbon_8 PF09723.5 EIW80268.1 - 0.04 13.8 4.0 0.04 13.8 2.8 2.6 2 1 1 3 3 3 0 Zinc ribbon domain C1_4 PF07975.7 EIW80268.1 - 0.045 13.7 2.8 0.045 13.7 1.9 2.6 1 1 2 3 3 3 0 TFIIH C1-like domain NOB1_Zn_bind PF08772.6 EIW80268.1 - 0.058 13.2 0.7 0.058 13.2 0.5 1.6 2 0 0 2 2 1 0 Nin one binding (NOB1) Zn-ribbon like Zn_Tnp_IS1595 PF12760.2 EIW80268.1 - 0.061 13.1 9.4 2.1 8.2 3.8 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zinc_ribbon_2 PF13240.1 EIW80268.1 - 0.098 12.1 7.2 0.11 11.9 0.1 3.2 3 0 0 3 3 3 0 zinc-ribbon domain Tmemb_55A PF09788.4 EIW80268.1 - 0.13 11.4 5.6 0.14 11.2 3.9 1.1 1 0 0 1 1 1 0 Transmembrane protein 55A SIR2 PF02146.12 EIW80268.1 - 0.35 10.5 2.4 0.47 10.1 1.7 1.2 1 0 0 1 1 1 0 Sir2 family zf-ribbon_3 PF13248.1 EIW80268.1 - 0.36 10.0 7.8 4.4 6.6 5.4 2.5 1 1 0 1 1 1 0 zinc-ribbon domain DZR PF12773.2 EIW80268.1 - 0.43 10.4 11.6 2.3 8.0 8.0 2.3 1 1 0 1 1 1 0 Double zinc ribbon RNA_POL_M_15KD PF02150.11 EIW80268.1 - 0.74 9.5 0.1 0.74 9.5 0.0 3.1 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Cys_rich_KTR PF14205.1 EIW80268.1 - 1.8 8.1 6.9 11 5.5 2.5 2.6 1 1 1 2 2 2 0 Cysteine-rich KTR zf-RING_3 PF14369.1 EIW80268.1 - 3.4 7.7 9.4 1.2 9.1 2.5 2.7 1 1 2 3 3 3 0 zinc-finger DNA_RNApol_7kD PF03604.8 EIW80268.1 - 4.3 6.8 7.0 46 3.5 3.3 3.0 2 1 1 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit DUF2296 PF10058.4 EIW80268.1 - 4.9 6.9 9.5 66 3.3 6.4 2.8 1 1 1 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) LIM PF00412.17 EIW80268.1 - 5.3 7.1 14.0 19 5.4 7.3 2.4 1 1 1 2 2 2 0 LIM domain Cytochrome_C7 PF14522.1 EIW80268.1 - 6.8 6.4 12.5 12 5.6 8.7 1.5 1 1 0 1 1 1 0 Cytochrome c7 Bac_rhodopsin PF01036.13 EIW80269.1 - 1.2e-41 142.5 21.0 1e-28 100.1 10.2 2.2 2 0 0 2 2 2 2 Bacteriorhodopsin-like protein BTB PF00651.26 EIW80270.1 - 8.8e-05 22.4 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF2263 PF10021.4 EIW80271.1 - 2e-29 102.5 0.0 2.9e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) BTB PF00651.26 EIW80272.1 - 0.00011 22.1 0.0 0.00018 21.4 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EIW80274.1 - 3.3e-09 36.7 0.0 4.9e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Mucin PF01456.12 EIW80274.1 - 9.9 5.9 12.8 15 5.3 8.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein HXXSHH PF07586.6 EIW80275.1 - 0.052 12.4 0.0 0.066 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Big_2 PF02368.13 EIW80278.1 - 0.091 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial Ig-like domain (group 2) FA_desaturase PF00487.19 EIW80280.1 - 1.9e-17 63.6 20.2 3.4e-17 62.7 14.0 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EIW80280.1 - 7.8e-13 48.0 0.0 4.3e-12 45.6 0.0 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Abhydrolase_6 PF12697.2 EIW80281.1 - 1.7e-25 90.2 0.0 2.3e-25 89.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW80281.1 - 1e-21 77.1 0.0 1.5e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIW80281.1 - 3.6e-19 68.3 0.0 2.8e-17 62.3 0.0 2.4 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EIW80281.1 - 3.7e-07 29.5 0.0 0.0017 17.6 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EIW80281.1 - 4e-07 29.8 0.0 1.3e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 EIW80281.1 - 0.0011 18.3 0.0 0.028 13.6 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Lipase_3 PF01764.20 EIW80281.1 - 0.0015 18.1 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_3 PF07859.8 EIW80281.1 - 0.0033 17.0 0.0 0.0057 16.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold AXE1 PF05448.7 EIW80281.1 - 0.0042 15.6 0.2 0.07 11.6 0.1 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Chlorophyllase2 PF12740.2 EIW80281.1 - 0.0086 14.9 0.0 0.023 13.5 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase enzyme PGAP1 PF07819.8 EIW80281.1 - 0.01 15.4 0.0 0.019 14.5 0.0 1.5 1 1 0 1 1 1 1 PGAP1-like protein DUF2974 PF11187.3 EIW80281.1 - 0.013 14.8 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) FSH1 PF03959.8 EIW80281.1 - 0.02 14.3 0.0 0.058 12.8 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Esterase PF00756.15 EIW80281.1 - 0.025 14.0 0.4 0.04 13.3 0.3 1.4 1 1 0 1 1 1 0 Putative esterase DUF2305 PF10230.4 EIW80281.1 - 0.034 13.5 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Tannase PF07519.6 EIW80281.1 - 0.059 12.0 0.0 0.32 9.6 0.0 1.9 2 0 0 2 2 2 0 Tannase and feruloyl esterase Hydrolase_4 PF12146.3 EIW80282.1 - 4.3e-20 71.3 0.2 5.1e-20 71.1 0.1 1.1 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 EIW80282.1 - 8.7e-07 29.0 0.9 1e-06 28.7 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW80282.1 - 1.4e-05 24.9 0.2 1.6e-05 24.6 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EIW80282.1 - 0.11 10.9 0.0 0.11 10.9 0.0 1.0 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) MANEC PF07502.9 EIW80284.1 - 0.06 13.3 1.3 0.3 11.1 0.7 2.1 2 0 0 2 2 2 0 MANEC domain L-fibroin PF05849.6 EIW80284.1 - 0.21 10.8 0.0 0.38 10.0 0.0 1.3 1 0 0 1 1 1 0 Fibroin light chain (L-fibroin) Abhydrolase_6 PF12697.2 EIW80286.1 - 6.2e-17 62.2 0.0 7.7e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW80286.1 - 2.2e-15 56.6 0.0 3.2e-15 56.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW80286.1 - 1.6e-05 24.5 0.0 0.00048 19.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIW80286.1 - 0.0002 20.6 0.0 0.016 14.4 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EIW80286.1 - 0.00047 19.8 0.0 0.00077 19.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EIW80286.1 - 0.0023 17.3 0.0 0.0032 16.9 0.0 1.5 1 1 0 1 1 1 1 Putative esterase LIP PF03583.9 EIW80286.1 - 0.0054 15.9 0.1 0.15 11.1 0.0 2.1 2 0 0 2 2 2 1 Secretory lipase Tannase PF07519.6 EIW80286.1 - 0.014 14.0 0.0 0.064 11.9 0.0 1.9 2 0 0 2 2 2 0 Tannase and feruloyl esterase AXE1 PF05448.7 EIW80286.1 - 0.018 13.5 0.0 2.9 6.2 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) DLH PF01738.13 EIW80286.1 - 0.034 13.4 0.0 0.47 9.7 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family FSH1 PF03959.8 EIW80286.1 - 0.039 13.4 0.0 0.078 12.4 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Esterase_phd PF10503.4 EIW80286.1 - 0.11 11.7 0.0 1.5 8.0 0.0 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase Peptidase_S15 PF02129.13 EIW80286.1 - 0.12 11.7 0.0 3.1 7.1 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Phage_Mu_Gam PF07352.7 EIW80286.1 - 0.2 11.1 0.6 3.8 7.0 0.0 2.3 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein BTB PF00651.26 EIW80287.1 - 3e-12 46.5 0.0 7.2e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Skp1_POZ PF03931.10 EIW80287.1 - 0.057 13.5 0.0 0.098 12.7 0.0 1.4 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Mito_carr PF00153.22 EIW80288.1 - 8e-16 57.5 0.9 9.3e-16 57.3 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein Cullin_Nedd8 PF10557.4 EIW80288.1 - 0.0066 16.2 0.2 0.01 15.6 0.2 1.4 1 1 0 1 1 1 1 Cullin protein neddylation domain Clathrin_lg_ch PF01086.12 EIW80289.1 - 3.5e-38 131.7 1.5 5.7e-38 131.0 1.0 1.3 1 0 0 1 1 1 1 Clathrin light chain DUF4407 PF14362.1 EIW80289.1 - 0.14 11.0 5.7 0.18 10.7 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L30_N PF08079.7 EIW80289.1 - 0.54 10.3 10.5 0.95 9.5 7.3 1.3 1 0 0 1 1 1 0 Ribosomal L30 N-terminal domain PGP_phosphatase PF09419.5 EIW80290.1 - 3.5e-47 159.8 0.0 4.9e-47 159.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase DDE_Tnp_1_4 PF13701.1 EIW80290.1 - 0.1 10.7 0.0 0.13 10.3 0.0 1.1 1 0 0 1 1 1 0 Transposase DDE domain group 1 ABC_membrane PF00664.18 EIW80291.1 - 1.4e-48 165.7 1.7 2.2e-48 165.0 1.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EIW80291.1 - 3.8e-29 101.7 0.0 9.6e-29 100.4 0.0 1.7 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EIW80291.1 - 0.00052 19.3 2.2 0.0055 15.9 0.0 2.1 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIW80291.1 - 0.0018 18.2 0.0 0.027 14.4 0.0 2.2 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EIW80291.1 - 0.011 14.8 0.0 0.026 13.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin SbcCD_C PF13558.1 EIW80291.1 - 0.062 13.2 0.3 0.3 11.0 0.2 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SUR7 PF06687.7 EIW80292.1 - 1.4e-09 37.8 18.8 2.1e-09 37.2 13.0 1.3 1 0 0 1 1 1 1 SUR7/PalI family Lipase_3 PF01764.20 EIW80293.1 - 1.8e-23 82.6 0.0 2.6e-23 82.2 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EIW80293.1 - 0.0014 18.5 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EIW80293.1 - 0.0017 17.9 0.0 0.0024 17.4 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein UPF0227 PF05728.7 EIW80293.1 - 0.0064 16.2 0.0 0.01 15.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.2 EIW80293.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW80293.1 - 0.015 14.8 0.0 0.028 13.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF915 PF06028.6 EIW80293.1 - 0.096 11.7 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) SUR7 PF06687.7 EIW80294.1 - 6.2e-14 52.0 14.8 8.9e-14 51.5 10.3 1.2 1 0 0 1 1 1 1 SUR7/PalI family zf-DHHC PF01529.15 EIW80294.1 - 0.43 9.9 1.7 0.87 8.9 1.2 1.7 1 1 0 1 1 1 0 DHHC palmitoyltransferase MRAP PF15183.1 EIW80294.1 - 0.92 9.1 3.4 17 5.1 1.0 2.6 2 0 0 2 2 2 0 Melanocortin-2 receptor accessory protein family RDD PF06271.7 EIW80294.1 - 1.4 8.8 15.7 0.74 9.7 6.0 2.2 1 1 1 2 2 2 0 RDD family DUF2156 PF09924.4 EIW80295.1 - 3.3e-15 55.6 0.0 7.6e-15 54.5 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) PTH2 PF01981.11 EIW80297.1 - 1.3e-05 24.8 0.3 3e-05 23.6 0.2 1.7 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 PCDO_beta_N PF12391.3 EIW80298.1 - 2.1 7.8 5.4 0.84 9.1 0.3 2.4 1 1 1 2 2 2 0 Protocatechuate 3,4-dioxygenase beta subunit N terminal DUF1240 PF06836.7 EIW80300.1 - 0.19 11.9 4.6 0.99 9.6 2.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) Vma12 PF11712.3 EIW80300.1 - 3.3 7.4 7.4 3 7.5 0.6 2.6 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase zf-C2H2 PF00096.21 EIW80301.1 - 4.6e-06 26.6 0.7 4.6e-06 26.6 0.5 2.2 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW80301.1 - 0.00029 20.9 0.5 0.00029 20.9 0.4 1.8 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIW80301.1 - 0.018 14.9 0.1 0.041 13.7 0.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIW80301.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EIW80301.1 - 0.086 13.1 6.5 0.45 10.8 0.3 2.9 3 0 0 3 3 3 0 Zinc-finger double domain Foie-gras_1 PF11817.3 EIW80303.1 - 3e-45 154.6 0.1 8.6e-44 149.8 0.0 2.6 2 1 0 2 2 2 1 Foie gras liver health family 1 Gryzun PF07919.7 EIW80303.1 - 1.1e-43 149.4 0.0 7.3e-25 87.3 0.0 2.1 1 1 0 2 2 2 2 Gryzun, putative trafficking through Golgi TPR_12 PF13424.1 EIW80303.1 - 0.0013 18.6 1.2 0.021 14.7 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Trs65 PF12735.2 EIW80303.1 - 0.011 15.0 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 TPR_6 PF13174.1 EIW80303.1 - 0.012 15.9 0.3 0.06 13.8 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat F-box-like PF12937.2 EIW80305.1 - 6.3e-08 32.2 2.8 3.2e-07 29.9 1.9 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EIW80305.1 - 3.1 7.5 6.1 1.9 8.2 0.1 3.1 4 0 0 4 4 4 0 F-box domain GST_N_3 PF13417.1 EIW80306.1 - 1.4e-23 82.9 0.0 2.8e-23 81.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW80306.1 - 1.2e-17 63.6 0.0 2.8e-17 62.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW80306.1 - 2.3e-08 34.1 0.0 4.3e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW80306.1 - 3.4e-05 23.7 0.0 8.4e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EIW80306.1 - 0.031 14.2 0.0 0.092 12.7 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin DUF2379 PF09543.5 EIW80306.1 - 0.069 13.1 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) p450 PF00067.17 EIW80307.1 - 9.8e-74 248.5 0.0 1.1e-73 248.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 YqzH PF14164.1 EIW80307.1 - 0.077 12.9 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 YqzH-like protein Nramp PF01566.13 EIW80308.1 - 4.3e-82 275.7 27.7 6.6e-80 268.5 9.5 3.4 3 1 0 3 3 3 2 Natural resistance-associated macrophage protein DUF912 PF06024.7 EIW80308.1 - 0.01 15.8 0.7 31 4.6 0.0 3.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3270 PF11674.3 EIW80308.1 - 0.89 9.6 6.2 0.11 12.5 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3270) ODV-E18 PF10717.4 EIW80308.1 - 1 8.8 4.1 0.59 9.6 0.0 2.6 3 0 0 3 3 3 0 Occlusion-derived virus envelope protein ODV-E18 Abhydrolase_6 PF12697.2 EIW80310.1 - 5.3e-05 23.2 0.2 9.2e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family FMN_dh PF01070.13 EIW80311.1 - 5.8e-121 403.6 0.0 7.2e-121 403.3 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EIW80311.1 - 4.2e-22 77.7 0.0 1.1e-21 76.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain IMPDH PF00478.20 EIW80311.1 - 1.2e-05 24.3 0.1 3.1e-05 23.0 0.1 1.6 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EIW80311.1 - 1.3e-05 24.2 0.0 2.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase ThiG PF05690.9 EIW80311.1 - 0.0042 16.1 0.0 0.32 10.0 0.0 2.2 2 0 0 2 2 2 1 Thiazole biosynthesis protein ThiG NMO PF03060.10 EIW80311.1 - 0.0099 15.0 0.1 0.016 14.4 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase DHO_dh PF01180.16 EIW80311.1 - 0.012 14.5 0.0 0.022 13.6 0.0 1.4 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase His_biosynth PF00977.16 EIW80311.1 - 0.025 13.8 0.2 0.094 11.9 0.0 2.0 3 0 0 3 3 3 0 Histidine biosynthesis protein PEP_mutase PF13714.1 EIW80312.1 - 3.9e-47 160.4 1.8 5e-47 160.1 1.2 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EIW80312.1 - 1e-19 70.1 0.2 1.4e-19 69.7 0.2 1.2 1 0 0 1 1 1 1 Isocitrate lyase family TIM-br_sig_trns PF09370.5 EIW80312.1 - 0.021 13.8 0.1 0.043 12.8 0.1 1.5 1 0 0 1 1 1 0 TIM-barrel signal transduction protein PGI PF00342.14 EIW80312.1 - 0.15 10.4 0.0 0.19 10.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoglucose isomerase FMN_dh PF01070.13 EIW80313.1 - 2.5e-118 395.0 0.0 3e-118 394.7 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EIW80313.1 - 2.2e-23 81.8 0.0 4.3e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EIW80313.1 - 0.0001 21.3 0.0 0.00016 20.7 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EIW80313.1 - 0.00048 19.1 0.0 0.00082 18.3 0.0 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Hexapep PF00132.19 EIW80314.1 - 5.8e-11 41.3 21.7 1.6e-07 30.5 1.6 4.2 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EIW80314.1 - 2.5e-07 30.1 14.7 0.00083 18.8 1.4 3.7 3 1 1 4 4 4 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EIW80314.1 - 0.0013 17.3 0.1 0.0022 16.6 0.1 1.3 1 0 0 1 1 1 1 L-fucokinase PapC_C PF13953.1 EIW80315.1 - 0.039 13.5 0.1 0.51 10.0 0.0 2.2 2 0 0 2 2 2 0 PapC C-terminal domain CD52 PF15116.1 EIW80315.1 - 5.5 6.8 7.0 19 5.1 4.9 1.9 1 0 0 1 1 1 0 CAMPATH-1 antigen BTB PF00651.26 EIW80316.1 - 6.8e-10 38.9 0.0 1.2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain RadC PF04002.10 EIW80316.1 - 0.097 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 RadC-like JAB domain VPS9 PF02204.13 EIW80318.1 - 4.2e-16 58.8 0.0 6.3e-15 55.0 0.0 2.4 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF3684 PF12449.3 EIW80319.1 - 3.2e-08 31.6 0.0 1.6e-06 26.0 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3684) Sad1_UNC PF07738.8 EIW80320.1 - 3.1e-16 59.3 0.0 4.8e-07 29.6 0.0 2.3 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal WD40 PF00400.27 EIW80321.1 - 0.0032 17.2 0.0 0.38 10.7 0.0 3.2 4 0 0 4 4 4 2 WD domain, G-beta repeat ATG13 PF10033.4 EIW80322.1 - 0.013 14.8 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 0 Autophagy-related protein 13 BRO1 PF03097.13 EIW80326.1 - 5.5e-38 130.6 0.2 2.2e-25 89.2 0.0 2.0 1 1 1 2 2 2 2 BRO1-like domain Glucan_synthase PF02364.10 EIW80328.1 - 3.6e-145 484.9 2.0 8.2e-115 384.5 0.2 4.0 1 1 3 4 4 4 4 1,3-beta-glucan synthase component DUF1875 PF08961.5 EIW80329.1 - 0.0033 16.7 4.2 0.0058 15.9 2.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1875) Macoilin PF09726.4 EIW80329.1 - 0.032 12.5 11.2 0.04 12.2 7.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Apolipoprotein PF01442.13 EIW80330.1 - 0.0023 17.4 6.6 0.0052 16.3 4.6 1.5 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain SF-assemblin PF06705.6 EIW80330.1 - 0.0043 16.2 5.4 0.0088 15.2 3.7 1.5 1 0 0 1 1 1 1 SF-assemblin/beta giardin CENP-K PF11802.3 EIW80330.1 - 0.026 13.7 3.4 0.058 12.6 2.4 1.5 1 0 0 1 1 1 0 Centromere-associated protein K TBPIP PF07106.8 EIW80330.1 - 0.25 10.8 7.0 0.89 9.0 0.7 2.5 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IZUMO PF15005.1 EIW80330.1 - 0.27 11.2 1.7 0.49 10.4 1.2 1.3 1 0 0 1 1 1 0 Izumo sperm-egg fusion Baculo_PEP_C PF04513.7 EIW80330.1 - 0.45 10.3 6.1 0.43 10.4 0.3 2.6 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4618 PF15397.1 EIW80330.1 - 0.5 9.6 7.3 1.3 8.2 5.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) DUF972 PF06156.8 EIW80330.1 - 0.97 9.8 8.3 0.42 10.9 0.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF972) Fib_alpha PF08702.5 EIW80330.1 - 3.8 7.6 9.0 1.3 9.1 3.5 2.2 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF883 PF05957.8 EIW80330.1 - 4.2 7.8 12.1 0.51 10.7 3.6 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Orthopox_A5L PF06193.6 EIW80331.1 - 0.032 14.1 2.5 0.042 13.7 0.0 2.2 2 1 0 2 2 2 0 Orthopoxvirus A5L protein-like WHEP-TRS PF00458.15 EIW80332.1 - 0.086 12.5 0.3 0.16 11.6 0.2 1.4 1 0 0 1 1 1 0 WHEP-TRS domain UPRTase PF14681.1 EIW80332.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase DUF4510 PF14971.1 EIW80334.1 - 0.0082 16.3 1.4 0.014 15.5 0.3 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4510) BTB PF00651.26 EIW80338.1 - 1.3e-06 28.3 0.0 3.5e-06 26.9 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain SMK-1 PF04802.10 EIW80339.1 - 7e-38 130.0 0.4 1.5e-37 129.0 0.2 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 zf-RING_5 PF14634.1 EIW80339.1 - 1.8e-05 24.3 3.4 0.00027 20.6 1.1 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EIW80339.1 - 4.4e-05 23.2 5.1 0.00032 20.4 1.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.1 EIW80339.1 - 6.5e-05 22.5 1.9 0.00026 20.6 1.3 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EIW80339.1 - 7.4e-05 22.6 3.5 7.4e-05 22.6 2.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW80339.1 - 0.00049 19.7 2.8 0.00049 19.7 1.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW80339.1 - 0.0015 18.1 5.8 0.013 15.1 1.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Myosin_tail_1 PF01576.14 EIW80339.1 - 0.0041 14.9 0.7 0.006 14.3 0.5 1.1 1 0 0 1 1 1 1 Myosin tail Lebercilin PF15619.1 EIW80339.1 - 0.014 14.7 0.5 0.026 13.9 0.3 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease zf-RING_6 PF14835.1 EIW80339.1 - 0.044 13.5 0.8 0.12 12.2 0.6 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Herpes_UL6 PF01763.11 EIW80339.1 - 0.047 11.8 0.8 0.085 11.0 0.6 1.3 1 0 0 1 1 1 0 Herpesvirus UL6 like zf-C3HC4_4 PF15227.1 EIW80339.1 - 0.091 12.6 8.6 0.033 14.0 3.0 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF972 PF06156.8 EIW80339.1 - 0.12 12.7 1.5 0.3 11.4 1.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DivIC PF04977.10 EIW80339.1 - 2 7.9 6.4 6.3 6.3 0.8 2.7 1 1 1 2 2 2 0 Septum formation initiator zf-PARP PF00645.13 EIW80341.1 - 1.2e-15 57.4 0.0 1.4e-15 57.3 0.0 1.0 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Crystall PF00030.14 EIW80341.1 - 0.095 12.6 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Beta/Gamma crystallin HET PF06985.6 EIW80342.1 - 3.4e-19 69.4 3.0 1.2e-15 57.8 0.0 2.8 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) DUF3809 PF12723.2 EIW80342.1 - 0.098 12.5 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3809) Glyco_hydro_71 PF03659.9 EIW80344.1 - 6.3e-100 334.3 14.3 7.4e-100 334.1 9.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 BTB PF00651.26 EIW80346.1 - 3.8e-07 30.0 0.0 1.2e-06 28.5 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain HSP70 PF00012.15 EIW80347.1 - 1.3e-264 878.6 14.7 1.6e-264 878.4 10.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIW80347.1 - 6.7e-15 54.5 6.1 1.1e-13 50.4 0.4 2.8 3 0 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.1 EIW80347.1 - 0.00038 20.2 11.1 0.27 11.0 0.3 4.8 4 1 0 4 4 4 2 Cell division protein FtsA FGGY_C PF02782.11 EIW80347.1 - 0.022 14.3 0.4 0.046 13.3 0.0 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain APH PF01636.18 EIW80348.1 - 1.7e-39 135.9 0.0 2.7e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIW80348.1 - 0.0016 18.0 0.0 0.006 16.1 0.0 1.8 2 0 0 2 2 2 1 Choline/ethanolamine kinase EcKinase PF02958.15 EIW80348.1 - 0.0019 17.4 0.0 0.0029 16.8 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase CBM_5_12 PF02839.9 EIW80350.1 - 4.7e-11 42.0 13.4 4.7e-11 42.0 9.3 3.3 3 0 0 3 3 3 2 Carbohydrate binding domain F-box-like PF12937.2 EIW80351.1 - 1.9e-08 33.8 0.1 7.3e-08 32.0 0.1 2.1 1 0 0 1 1 1 1 F-box-like NAD_binding_6 PF08030.7 EIW80352.1 - 2.4e-13 50.2 0.0 1e-06 28.7 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EIW80352.1 - 7e-13 48.7 18.3 7e-13 48.7 12.7 2.5 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EIW80352.1 - 3.9e-11 42.7 0.0 2.4e-10 40.2 0.0 2.2 2 0 0 2 2 2 1 FAD-binding domain Abhydrolase_3 PF07859.8 EIW80353.1 - 1.3e-38 132.7 0.0 3.9e-31 108.2 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EIW80353.1 - 1.6e-09 36.9 0.0 2.8e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EIW80353.1 - 0.002 17.8 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EIW80353.1 - 0.055 12.1 0.0 0.35 9.5 0.0 2.1 2 0 0 2 2 2 0 Carboxylesterase family Glyco_hydro_12 PF01670.11 EIW80354.1 - 3.2e-33 114.7 4.4 3.2e-33 114.7 3.1 1.8 1 1 1 2 2 2 1 Glycosyl hydrolase family 12 DUF3040 PF11239.3 EIW80355.1 - 0.002 18.1 1.4 0.17 11.9 0.0 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3040) MFS_1 PF07690.11 EIW80357.1 - 5.9e-29 100.8 23.4 5.9e-29 100.8 16.2 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EIW80357.1 - 4.7e-06 25.2 17.6 0.0014 17.0 4.9 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.19 EIW80357.1 - 7.8e-06 24.7 8.4 7.8e-06 24.7 5.8 2.3 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EIW80357.1 - 0.0022 16.2 1.2 0.0022 16.2 0.8 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EIW80358.1 - 3.9e-29 101.4 23.4 3.9e-29 101.4 16.2 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIW80358.1 - 4.6e-06 25.1 0.7 8.5e-06 24.2 0.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIW80358.1 - 1.8e-05 23.5 1.6 1.8e-05 23.5 1.1 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter DUF3341 PF11821.3 EIW80358.1 - 0.0045 16.4 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3341) ATG22 PF11700.3 EIW80358.1 - 2.5 6.4 18.5 0.017 13.6 4.2 3.2 2 2 1 3 3 3 0 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EIW80359.1 - 1.7e-29 102.6 23.8 1.7e-29 102.6 16.5 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW80359.1 - 1.4e-06 27.2 7.7 1.4e-06 27.2 5.4 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EIW80359.1 - 1.4e-05 23.5 1.7 2.3e-05 22.8 1.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF3341 PF11821.3 EIW80359.1 - 0.075 12.4 0.2 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3341) Aa_trans PF01490.13 EIW80361.1 - 0.093 11.1 0.2 0.76 8.1 0.0 2.1 2 0 0 2 2 2 0 Transmembrane amino acid transporter protein F-box-like PF12937.2 EIW80363.1 - 0.026 14.2 1.4 0.043 13.5 0.1 2.0 2 0 0 2 2 2 0 F-box-like adh_short PF00106.20 EIW80364.1 - 1.6e-22 80.2 0.2 2.5e-22 79.5 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW80364.1 - 3.2e-09 36.9 0.0 7.5e-09 35.7 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW80364.1 - 2.5e-08 33.7 0.6 7.6e-08 32.2 0.4 1.7 1 1 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 EIW80364.1 - 0.031 13.4 0.1 0.056 12.5 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EIW80364.1 - 0.094 12.3 0.4 0.14 11.7 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkH PF02386.11 EIW80365.1 - 1.9e-96 322.7 17.3 1.7e-93 313.0 6.8 2.1 2 0 0 2 2 2 2 Cation transport protein Hum_adeno_E3A PF05393.6 EIW80365.1 - 0.076 12.6 3.9 0.37 10.4 0.1 3.1 3 0 0 3 3 3 0 Human adenovirus early E3A glycoprotein MIF4G PF02854.14 EIW80366.1 - 1.8e-58 197.3 0.6 4e-58 196.2 0.4 1.6 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EIW80366.1 - 1.8e-17 63.0 0.0 6.3e-17 61.2 0.0 2.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MA3 PF02847.12 EIW80366.1 - 9.7e-06 25.2 0.1 2.8e-05 23.7 0.1 1.8 1 0 0 1 1 1 1 MA3 domain Arrestin_C PF02752.17 EIW80367.1 - 4.3e-16 59.2 0.0 1.9e-15 57.1 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EIW80367.1 - 2.6e-13 50.0 0.1 6.6e-10 38.9 0.0 2.6 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Nramp PF01566.13 EIW80368.1 - 4.3e-74 249.4 18.9 4.3e-74 249.4 13.1 2.4 2 1 0 2 2 2 1 Natural resistance-associated macrophage protein DUF912 PF06024.7 EIW80368.1 - 0.092 12.8 1.8 0.79 9.8 0.0 3.1 3 1 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) LCM PF04072.9 EIW80369.1 - 9.3e-23 80.7 0.3 2e-22 79.6 0.2 1.5 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase DUF150 PF02576.12 EIW80369.1 - 0.038 13.5 0.0 10 5.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised BCR, YhbC family COG0779 UPF0104 PF03706.8 EIW80370.1 - 2.8e-05 23.5 1.9 0.003 16.8 0.2 2.1 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0104) Claudin_2 PF13903.1 EIW80370.1 - 0.077 12.6 3.7 0.11 12.2 0.4 2.2 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF4231 PF14015.1 EIW80370.1 - 1 9.3 8.0 2.8 7.9 1.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Peptidase_M1 PF01433.15 EIW80374.1 - 1.6e-110 369.8 0.3 5.5e-68 229.8 0.1 2.3 1 1 1 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 EIW80374.1 - 4.2e-51 174.1 0.0 6e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EIW80374.1 - 4.3e-14 52.6 0.2 1.2e-13 51.2 0.0 1.8 2 0 0 2 2 2 1 Peptidase MA superfamily Amidase PF01425.16 EIW80375.1 - 7.8e-23 81.0 0.0 1.3e-13 50.6 0.1 2.0 2 0 0 2 2 2 2 Amidase MRP_L53 PF10780.4 EIW80375.1 - 0.091 12.7 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 39S ribosomal protein L53/MRP-L53 Amidohydro_1 PF01979.15 EIW80376.1 - 3.7e-16 59.7 0.0 7.8e-12 45.4 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EIW80376.1 - 1.7e-15 57.8 0.6 3.4e-07 30.5 0.0 2.3 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EIW80376.1 - 2.2e-06 27.1 0.0 4.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EIW80376.1 - 0.00012 21.7 0.0 0.00035 20.3 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidase PF01425.16 EIW80377.1 - 3.6e-89 299.6 0.0 4.3e-89 299.3 0.0 1.1 1 0 0 1 1 1 1 Amidase CTP_transf_2 PF01467.21 EIW80378.1 - 1.1e-24 87.2 0.0 1.4e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase bZIP_1 PF00170.16 EIW80379.1 - 2.7e-07 30.4 5.5 2.7e-07 30.4 3.8 2.0 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EIW80379.1 - 5.9e-05 22.8 6.9 5.9e-05 22.8 4.8 2.1 1 1 1 2 2 2 1 Basic region leucine zipper DUF3496 PF12001.3 EIW80379.1 - 0.077 13.2 1.0 0.13 12.5 0.4 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3496) DNA_pol_B_thumb PF14791.1 EIW80380.1 - 5.4e-22 77.2 0.1 1.8e-21 75.5 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_B_palm PF14792.1 EIW80380.1 - 2.7e-15 56.3 0.0 6.1e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta palm HHH_8 PF14716.1 EIW80380.1 - 5.5e-10 39.2 0.1 2.3e-08 34.0 0.1 3.1 3 0 0 3 3 3 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 EIW80380.1 - 3.8e-07 29.5 0.0 1e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 EIW80380.1 - 0.00039 20.5 0.0 0.004 17.2 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EIW80380.1 - 0.0023 18.2 0.0 0.0092 16.2 0.0 2.1 1 1 0 1 1 1 1 Nucleotidyltransferase domain Cdd1 PF11731.3 EIW80380.1 - 0.043 13.7 0.0 0.13 12.1 0.0 1.7 1 1 0 1 1 1 0 Pathogenicity locus IMS_HHH PF11798.3 EIW80380.1 - 0.11 12.5 0.0 0.39 10.8 0.0 1.9 2 0 0 2 2 2 0 IMS family HHH motif Acyl-CoA_dh_1 PF00441.19 EIW80381.1 - 1.4e-22 80.3 0.1 2.3e-22 79.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EIW80381.1 - 4.8e-22 77.2 0.1 1.2e-21 75.9 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EIW80381.1 - 2.6e-21 76.3 0.0 5.1e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EIW80381.1 - 1.7e-05 25.0 0.0 2.8e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain F-box-like PF12937.2 EIW80382.1 - 0.00041 20.0 0.0 0.0014 18.3 0.0 2.0 1 1 0 1 1 1 1 F-box-like FLILHELTA PF10306.4 EIW80383.1 - 4.1e-09 36.3 0.0 6.9e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 EIW80383.1 - 0.0087 16.3 0.0 0.013 15.7 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) UPF0029 PF01205.14 EIW80384.1 - 8.4e-18 64.0 0.0 2e-17 62.8 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 DUF221 PF02714.10 EIW80389.1 - 1.3e-89 300.2 19.5 1.3e-89 300.2 13.5 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EIW80389.1 - 1.1e-37 128.9 0.8 1.1e-37 128.9 0.5 2.9 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EIW80389.1 - 1e-12 48.3 0.0 1.9e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) HET PF06985.6 EIW80390.1 - 1.7e-18 67.1 5.1 9.2e-16 58.2 0.4 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) F-box-like PF12937.2 EIW80391.1 - 8.7e-07 28.5 2.8 2.2e-06 27.2 1.9 1.7 1 0 0 1 1 1 1 F-box-like Steroid_dh PF02544.11 EIW80392.1 - 1.1e-28 99.8 7.2 5.4e-26 91.1 5.0 3.1 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EIW80392.1 - 3.6e-05 23.1 0.3 5.8e-05 22.5 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Rer1 PF03248.8 EIW80394.1 - 2.1e-77 258.7 1.8 2.6e-77 258.4 1.2 1.0 1 0 0 1 1 1 1 Rer1 family Lentiviral_Tat PF02998.9 EIW80394.1 - 0.054 13.3 0.6 0.094 12.5 0.0 1.7 2 0 0 2 2 2 0 Lentiviral Tat protein 2TM PF13239.1 EIW80394.1 - 0.21 11.6 4.3 0.7 9.9 1.0 2.2 2 0 0 2 2 2 0 2TM domain AAA_17 PF13207.1 EIW80395.1 - 9.6e-05 23.1 0.5 0.0016 19.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIW80395.1 - 0.0043 17.0 0.1 0.0073 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EIW80395.1 - 0.013 14.8 0.0 0.025 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EIW80395.1 - 0.029 14.0 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.9 EIW80395.1 - 0.044 13.5 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.9 EIW80395.1 - 0.07 12.1 0.0 0.07 12.1 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain IstB_IS21 PF01695.12 EIW80395.1 - 0.1 12.0 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_30 PF13604.1 EIW80395.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIW80395.1 - 0.12 12.7 0.0 0.55 10.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EIW80395.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.3 1 0 0 1 1 1 0 RNA helicase SRP54 PF00448.17 EIW80395.1 - 0.16 11.4 0.0 0.7 9.3 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain YtxC PF08812.6 EIW80395.1 - 0.2 11.1 0.3 0.27 10.7 0.2 1.1 1 0 0 1 1 1 0 YtxC-like family Glyco_hydro_cc PF11790.3 EIW80397.1 - 1.9e-33 115.9 0.3 2.5e-33 115.4 0.2 1.2 1 1 0 1 1 1 1 Glycosyl hydrolase catalytic core LPAM_1 PF08139.7 EIW80397.1 - 0.63 10.3 2.9 1.5 9.1 2.0 1.7 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Thaumatin PF00314.12 EIW80398.1 - 4.7e-15 55.6 10.2 5.5e-15 55.4 7.1 1.1 1 0 0 1 1 1 1 Thaumatin family zf-CCCH_2 PF14608.1 EIW80400.1 - 5.9e-10 38.7 30.0 0.0023 17.8 1.8 4.3 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type GATase PF00117.23 EIW80401.1 - 0.0016 17.9 0.0 0.0058 16.0 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EIW80401.1 - 0.002 17.5 0.0 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase C26 Peptidase_C26 PF07722.8 EIW80402.1 - 0.0019 17.6 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.23 EIW80402.1 - 0.0023 17.4 0.0 0.0061 16.0 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I RhoGAP PF00620.22 EIW80404.1 - 1e-09 38.1 0.0 2.3e-05 24.0 0.0 2.3 2 0 0 2 2 2 2 RhoGAP domain Oxidored_FMN PF00724.15 EIW80405.1 - 2e-57 194.7 0.0 1.2e-34 119.8 0.0 2.0 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family MTTB PF06253.6 EIW80406.1 - 0.15 9.7 0.0 0.22 9.2 0.0 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) Cwf_Cwc_15 PF04889.7 EIW80408.1 - 7.7e-72 241.9 22.1 1.1e-71 241.4 15.3 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein CDC45 PF02724.9 EIW80408.1 - 0.0023 16.0 17.6 0.0033 15.5 12.2 1.2 1 0 0 1 1 1 1 CDC45-like protein CENP-T PF15511.1 EIW80408.1 - 0.0033 16.7 19.3 0.0035 16.6 13.4 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Nop14 PF04147.7 EIW80408.1 - 0.014 13.4 30.4 0.017 13.1 21.1 1.1 1 0 0 1 1 1 0 Nop14-like family Smac_DIABLO PF09057.5 EIW80408.1 - 0.068 12.2 0.1 0.068 12.2 0.1 1.8 2 0 0 2 2 2 0 Second Mitochondria-derived Activator of Caspases ELH PF02323.10 EIW80408.1 - 0.22 10.6 10.6 0.17 11.0 1.1 2.2 1 1 1 2 2 2 0 Egg-laying hormone precursor TFIIF_alpha PF05793.7 EIW80408.1 - 0.23 9.8 30.0 0.24 9.6 19.3 2.0 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF2457 PF10446.4 EIW80408.1 - 0.41 9.3 26.6 0.57 8.8 18.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Dsh_C PF12316.3 EIW80408.1 - 0.68 10.0 2.8 0.53 10.3 0.4 1.8 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal Glypican PF01153.14 EIW80408.1 - 0.76 8.3 4.4 0.95 7.9 3.1 1.2 1 0 0 1 1 1 0 Glypican Daxx PF03344.10 EIW80408.1 - 1.2 7.5 27.5 1.5 7.2 19.1 1.1 1 0 0 1 1 1 0 Daxx Family SAPS PF04499.10 EIW80408.1 - 1.6 7.3 8.9 1.8 7.1 6.2 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PseudoU_synth_2 PF00849.17 EIW80409.1 - 2.5e-27 95.7 0.0 3.8e-27 95.1 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Uso1_p115_head PF04869.9 EIW80411.1 - 4.4e-48 163.6 0.0 2e-46 158.2 0.0 2.7 3 1 0 3 3 3 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EIW80411.1 - 1.5e-07 31.4 32.1 3.1e-07 30.4 22.3 1.5 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, C terminal region Cnd1 PF12717.2 EIW80411.1 - 0.0069 16.2 0.4 0.049 13.4 0.3 2.4 1 1 0 1 1 1 1 non-SMC mitotic condensation complex subunit 1 Xpo1 PF08389.7 EIW80411.1 - 0.06 13.2 0.0 2.1 8.2 0.0 3.0 2 0 0 2 2 2 0 Exportin 1-like protein zf-ZPR1 PF03367.8 EIW80411.1 - 0.38 9.8 3.9 0.91 8.6 2.4 1.8 1 1 0 1 1 1 0 ZPR1 zinc-finger domain HEAT PF02985.17 EIW80411.1 - 0.83 9.8 5.1 11 6.4 0.0 3.4 3 0 0 3 3 3 0 HEAT repeat DUF3361 PF11841.3 EIW80411.1 - 2.2 7.9 7.2 1.2 8.7 0.2 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF3361) Cwf_Cwc_15 PF04889.7 EIW80411.1 - 5.3 6.6 24.5 8.6 5.9 17.0 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BTV_NS2 PF04514.7 EIW80411.1 - 8.1 5.2 19.4 12 4.6 13.4 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FLO_LFY PF01698.11 EIW80411.1 - 8.9 5.0 14.2 13 4.5 9.9 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein p450 PF00067.17 EIW80412.1 - 1.6e-70 237.9 0.0 7.6e-70 235.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW80413.1 - 1.2e-65 221.8 0.0 3.6e-65 220.2 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 EIW80414.1 - 4.2e-12 45.7 0.1 9.3e-05 21.9 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain BBE PF08031.7 EIW80414.1 - 5.9e-07 29.2 0.0 2e-05 24.3 0.0 2.3 2 0 0 2 2 2 1 Berberine and berberine like ALO PF04030.9 EIW80414.1 - 0.023 14.2 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase RhoGEF PF00621.15 EIW80415.1 - 3.7e-26 92.0 0.0 1.1e-23 84.0 0.0 3.0 2 1 0 2 2 2 2 RhoGEF domain Oxidored_molyb PF00174.14 EIW80416.1 - 9.7e-32 109.7 0.0 1.5e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EIW80416.1 - 1.3e-07 31.3 2.2 2.4e-07 30.4 1.5 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Gmad2 PF10648.4 EIW80416.1 - 0.0059 16.7 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 Immunoglobulin-like domain of bacterial spore germination RRM_6 PF14259.1 EIW80418.1 - 4e-37 126.0 0.7 2.4e-10 40.2 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIW80418.1 - 2.9e-28 97.2 4.6 6.4e-09 35.3 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW80418.1 - 1.3e-19 69.7 0.0 0.00053 19.7 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIW80418.1 - 3e-05 23.7 0.1 0.066 13.0 0.1 2.5 2 0 0 2 2 2 2 RNA binding motif DUF1866 PF08952.6 EIW80418.1 - 0.0017 17.8 0.0 1.6 8.2 0.0 3.2 3 1 1 4 4 4 2 Domain of unknown function (DUF1866) Rot1 PF10681.4 EIW80419.1 - 1.4e-53 181.4 0.5 1.6e-53 181.1 0.3 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal UPF0014 PF03649.8 EIW80420.1 - 9.9e-35 119.8 17.9 1.6e-32 112.6 12.4 2.1 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0014) DUF4231 PF14015.1 EIW80420.1 - 0.041 13.8 0.2 0.041 13.8 0.2 3.3 2 2 2 4 4 4 0 Protein of unknown function (DUF4231) F-box-like PF12937.2 EIW80423.1 - 2.8e-06 26.9 0.4 1.9e-05 24.2 0.3 2.3 1 1 0 1 1 1 1 F-box-like EF-hand_1 PF00036.27 EIW80424.1 - 0.0014 17.8 0.5 0.011 14.9 0.1 2.8 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EIW80424.1 - 0.0017 18.0 0.1 0.014 15.1 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain DivIVA PF05103.8 EIW80424.1 - 0.47 10.5 6.4 1.5 8.8 0.0 3.5 4 0 0 4 4 4 0 DivIVA protein DUF3350 PF11830.3 EIW80425.1 - 0.11 12.5 0.4 0.28 11.2 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3350) Integrin_b_cyt PF08725.6 EIW80425.1 - 0.17 11.3 1.0 8.2 5.9 0.1 3.1 2 1 0 2 2 2 0 Integrin beta cytoplasmic domain Sugar_tr PF00083.19 EIW80426.1 - 1.3e-94 317.3 18.4 5e-92 308.8 12.8 2.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW80426.1 - 1.1e-19 70.4 49.0 3.7e-17 62.0 13.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_4 PF07721.9 EIW80426.1 - 0.065 13.6 0.8 0.29 11.6 0.6 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat SET PF00856.23 EIW80429.1 - 6e-18 65.6 0.0 6e-18 65.6 0.0 2.9 3 2 0 3 3 3 1 SET domain NAD_binding_4 PF07993.7 EIW80431.1 - 6.5e-26 90.7 0.0 9.2e-26 90.2 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EIW80431.1 - 1.1e-10 41.3 0.0 1.7e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIW80431.1 - 0.0013 17.4 0.0 0.012 14.3 0.0 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DXP_reductoisom PF02670.11 EIW80431.1 - 0.17 12.4 0.0 0.29 11.6 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_6 PF08030.7 EIW80432.1 - 1.5e-15 57.3 0.0 2.5e-15 56.7 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EIW80432.1 - 1e-13 51.0 0.0 2.8e-13 49.6 0.0 1.7 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 EIW80432.1 - 3.5e-08 33.5 7.6 3.5e-08 33.5 5.3 2.2 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EIW80432.1 - 0.055 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain MFS_1 PF07690.11 EIW80434.1 - 6e-21 74.5 49.9 1.6e-14 53.3 18.5 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW80434.1 - 6.4e-05 21.7 12.6 6.4e-05 21.7 8.7 3.0 2 2 1 3 3 3 1 Sugar (and other) transporter F-box PF00646.28 EIW80435.1 - 4.5e-06 26.1 0.0 1e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW80435.1 - 0.012 15.3 0.5 0.027 14.1 0.3 1.6 1 0 0 1 1 1 0 F-box-like SHS2_Rpb7-N PF03876.12 EIW80435.1 - 0.1 12.7 0.0 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 GST_N_3 PF13417.1 EIW80440.1 - 3.3e-12 46.4 0.0 5e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW80440.1 - 3.7e-10 39.8 0.0 5.9e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW80440.1 - 6e-08 32.5 0.0 9.3e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW80443.1 - 4.4e-07 29.9 0.0 8e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EIW80443.1 - 6e-07 29.5 0.0 1.9e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW80443.1 - 0.0014 18.5 0.0 0.0079 16.1 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Mem_trans PF03547.13 EIW80444.1 - 0.037 12.3 0.0 0.36 9.0 0.0 2.3 2 1 0 2 2 2 0 Membrane transport protein DUF3759 PF12585.3 EIW80449.1 - 1.2e-31 108.4 5.1 1.3e-31 108.3 3.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) HlyIII PF03006.15 EIW80450.1 - 7e-52 176.0 17.9 8.6e-52 175.7 12.4 1.1 1 0 0 1 1 1 1 Haemolysin-III related TilS_C PF11734.3 EIW80450.1 - 0.024 13.8 0.1 0.065 12.4 0.0 1.7 1 0 0 1 1 1 0 TilS substrate C-terminal domain DUF3483 PF11982.3 EIW80450.1 - 0.039 13.2 0.3 0.091 12.0 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) TFIIS_C PF01096.13 EIW80451.1 - 4.9e-18 64.4 3.4 4.9e-18 64.4 2.3 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EIW80451.1 - 1.4e-08 34.2 8.6 1.7e-08 33.9 0.3 3.1 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 EIW80451.1 - 0.028 14.2 11.7 0.073 12.8 0.4 2.8 2 1 0 2 2 2 0 Transposase zinc-ribbon domain UPF0547 PF10571.4 EIW80451.1 - 0.029 14.0 8.1 0.51 10.0 0.2 3.9 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-TFIIB PF13453.1 EIW80451.1 - 0.038 13.1 5.4 0.14 11.3 0.1 2.9 3 0 0 3 3 3 0 Transcription factor zinc-finger DZR PF12773.2 EIW80451.1 - 0.1 12.4 10.3 0.71 9.7 0.4 2.5 2 1 0 2 2 2 0 Double zinc ribbon PhnA_Zn_Ribbon PF08274.7 EIW80451.1 - 0.14 11.9 12.0 4.3 7.2 0.1 3.7 3 1 1 4 4 4 0 PhnA Zinc-Ribbon Baculo_LEF5_C PF11792.3 EIW80451.1 - 0.15 11.4 3.9 0.26 10.6 1.1 2.5 2 1 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain zf-RING_3 PF14369.1 EIW80451.1 - 0.15 12.0 8.7 2 8.4 0.7 3.1 3 0 0 3 3 3 0 zinc-finger DUF2387 PF09526.5 EIW80451.1 - 0.58 10.1 9.4 1.5 8.8 0.4 2.9 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) Cytochrom_c3_2 PF14537.1 EIW80451.1 - 1.4 9.2 5.2 1.7 9.0 3.2 1.5 1 1 0 1 1 1 0 Cytochrome c3 Rep_fac-A_C PF08646.5 EIW80451.1 - 1.6 8.4 6.5 0.51 10.0 0.4 2.2 1 1 1 2 2 2 0 Replication factor-A C terminal domain zf-CHY PF05495.7 EIW80451.1 - 2.4 8.3 10.4 9.7 6.4 2.1 2.5 1 1 1 2 2 2 0 CHY zinc finger Zn-ribbon_8 PF09723.5 EIW80451.1 - 3.8 7.5 11.6 16 5.5 2.8 3.8 3 1 1 4 4 4 0 Zinc ribbon domain CIAPIN1 PF05093.8 EIW80451.1 - 5.4 7.1 6.8 1 9.4 0.8 2.0 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DnaJ_CXXCXGXG PF00684.14 EIW80451.1 - 6.1 6.9 11.7 0.51 10.4 2.2 2.7 2 2 0 2 2 2 0 DnaJ central domain Methyltransf_31 PF13847.1 EIW80452.1 - 2.1e-27 95.6 0.0 3.4e-27 94.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW80452.1 - 7.3e-19 68.0 0.0 1.8e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW80452.1 - 6.8e-16 58.8 0.0 1.6e-15 57.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW80452.1 - 5.9e-14 51.7 0.0 1.8e-13 50.1 0.0 1.6 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EIW80452.1 - 2.8e-13 50.0 0.0 1.3e-12 47.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW80452.1 - 6.4e-13 48.7 0.0 1.8e-12 47.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW80452.1 - 8.1e-13 48.6 0.0 1.7e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW80452.1 - 9.4e-11 41.7 0.2 3.3e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EIW80452.1 - 1.7e-09 37.2 0.0 3.2e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Rhodanese PF00581.15 EIW80452.1 - 9e-08 32.4 0.0 2e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain MTS PF05175.9 EIW80452.1 - 7.4e-07 28.6 0.0 1.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_24 PF13578.1 EIW80452.1 - 5.4e-06 27.1 0.2 0.00049 20.8 0.0 3.0 3 1 0 3 3 2 1 Methyltransferase domain CMAS PF02353.15 EIW80452.1 - 9e-05 21.6 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EIW80452.1 - 0.00024 20.6 0.0 0.00066 19.2 0.0 1.7 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.13 EIW80452.1 - 0.00047 19.4 0.0 0.0011 18.1 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_8 PF05148.10 EIW80452.1 - 0.0021 17.7 0.0 0.0038 16.8 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_16 PF10294.4 EIW80452.1 - 0.026 14.0 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_29 PF03141.11 EIW80452.1 - 0.032 12.5 0.0 0.052 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.12 EIW80452.1 - 0.041 12.9 0.0 0.43 9.6 0.0 2.1 2 0 0 2 2 2 0 Putative methyltransferase DUF938 PF06080.7 EIW80452.1 - 0.059 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) UPF0020 PF01170.13 EIW80452.1 - 0.06 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 TPMT PF05724.6 EIW80452.1 - 0.082 12.3 0.0 0.27 10.6 0.0 1.8 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) DOT1 PF08123.8 EIW80452.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.6 1 1 0 1 1 1 0 Histone methylation protein DOT1 DUF4486 PF14858.1 EIW80453.1 - 0.016 13.4 0.1 0.031 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4486) Flavoprotein PF02441.14 EIW80453.1 - 0.043 13.4 0.0 0.085 12.5 0.0 1.6 1 0 0 1 1 1 0 Flavoprotein FCH PF00611.18 EIW80454.1 - 9.1e-20 70.6 0.2 9.1e-20 70.6 0.1 2.9 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EIW80454.1 - 4.7e-11 41.8 0.1 8.1e-11 41.1 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIW80454.1 - 9.2e-10 37.9 0.1 1.7e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIW80454.1 - 2.1e-05 23.8 0.0 4.7e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain F-box PF00646.28 EIW80455.1 - 5.1e-05 22.7 0.1 9.7e-05 21.9 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 EIW80455.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 F-box-like domain BTB PF00651.26 EIW80456.1 - 3e-06 27.1 0.0 4.6e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain Pyr_redox_2 PF07992.9 EIW80458.1 - 0.0036 17.2 0.0 0.0036 17.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW80458.1 - 0.016 14.1 0.0 0.018 13.9 0.0 1.0 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Gly_transf_sug PF04488.10 EIW80460.1 - 4.4e-06 27.0 0.1 1.5e-05 25.2 0.1 1.9 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EIW80460.1 - 0.00051 19.2 0.3 0.00051 19.2 0.2 1.7 2 0 0 2 2 2 1 Capsular polysaccharide synthesis protein TcdA_TcdB PF12919.2 EIW80460.1 - 0.12 10.8 0.0 0.17 10.3 0.0 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain MFS_1 PF07690.11 EIW80461.1 - 9.6e-29 100.1 28.9 9.6e-29 100.1 20.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily EF-hand_1 PF00036.27 EIW80464.1 - 1.2e-14 52.4 3.7 6.3e-05 21.9 0.0 4.3 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 EIW80464.1 - 1.6e-13 50.5 0.3 0.0036 17.4 0.0 3.6 3 1 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 EIW80464.1 - 1.6e-12 46.1 0.7 0.00017 21.1 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 EIW80464.1 - 9e-07 28.4 0.7 0.00031 20.2 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EIW80464.1 - 4.1e-06 25.9 0.6 0.19 11.1 0.0 3.3 3 0 0 3 3 3 2 EF hand Bromodomain PF00439.20 EIW80465.1 - 3.2e-20 71.8 0.2 7.6e-20 70.6 0.2 1.6 1 0 0 1 1 1 1 Bromodomain Bromo_TP PF07524.8 EIW80465.1 - 0.0012 18.5 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated WD40 PF00400.27 EIW80466.1 - 3e-28 96.6 12.8 4.6e-06 26.2 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EIW80466.1 - 0.0023 17.6 0.0 0.035 13.8 0.0 2.2 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A NACHT PF05729.7 EIW80467.1 - 6.3e-10 38.9 0.2 4.5e-09 36.1 0.0 2.6 4 0 0 4 4 4 1 NACHT domain AAA_16 PF13191.1 EIW80467.1 - 7.8e-10 39.0 0.1 3.3e-09 36.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain APS_kinase PF01583.15 EIW80467.1 - 0.0011 18.6 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.1 EIW80467.1 - 0.0012 19.6 0.1 0.014 16.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EIW80467.1 - 0.0014 18.7 0.0 0.0074 16.4 0.0 2.3 4 0 0 4 4 2 1 AAA domain AAA_18 PF13238.1 EIW80467.1 - 0.0023 18.2 0.0 0.0064 16.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EIW80467.1 - 0.0027 17.8 0.0 0.0069 16.5 0.0 1.7 1 0 0 1 1 1 1 RNA helicase MobB PF03205.9 EIW80467.1 - 0.0028 17.3 0.0 0.0053 16.4 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B PRK PF00485.13 EIW80467.1 - 0.0031 17.0 0.0 0.0051 16.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family ABC_tran PF00005.22 EIW80467.1 - 0.0042 17.4 0.1 0.012 15.9 0.0 1.8 2 0 0 2 2 1 1 ABC transporter Zeta_toxin PF06414.7 EIW80467.1 - 0.0065 15.5 0.1 0.028 13.4 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_10 PF12846.2 EIW80467.1 - 0.011 15.1 0.0 0.056 12.8 0.0 2.3 1 1 0 1 1 1 0 AAA-like domain Arch_ATPase PF01637.13 EIW80467.1 - 0.013 15.1 0.2 0.047 13.3 0.0 1.9 2 0 0 2 2 2 0 Archaeal ATPase AAA_29 PF13555.1 EIW80467.1 - 0.028 13.9 0.1 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EIW80467.1 - 0.036 13.9 0.0 0.099 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EIW80467.1 - 0.065 12.9 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 NTPase DUF258 PF03193.11 EIW80467.1 - 0.11 11.7 0.0 0.24 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EIW80467.1 - 0.13 11.7 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family GST_N_3 PF13417.1 EIW80468.1 - 1e-15 57.6 0.0 1.7e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW80468.1 - 4.3e-14 52.2 0.0 6.8e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW80468.1 - 2.9e-12 46.5 0.0 4.2e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW80468.1 - 1.5e-08 34.4 0.0 2.7e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW80468.1 - 1.8e-08 34.1 0.0 3.6e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW80468.1 - 0.00075 19.9 0.0 0.001 19.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Saccharop_dh PF03435.13 EIW80470.1 - 1.8e-07 30.5 0.0 1.8e-07 30.5 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase eIF-3c_N PF05470.7 EIW80472.1 - 0.21 9.6 2.2 0.33 8.9 1.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Saccharop_dh PF03435.13 EIW80474.1 - 1.1e-25 90.5 0.2 1.6e-25 89.9 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EIW80474.1 - 7e-09 35.9 0.3 1.1e-08 35.3 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW80474.1 - 1.6e-06 27.7 0.2 2.2e-05 24.0 0.1 2.1 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EIW80474.1 - 2.4e-06 27.5 1.7 5.2e-06 26.4 0.5 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Shikimate_DH PF01488.15 EIW80474.1 - 7e-06 26.1 0.0 1.6e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.14 EIW80474.1 - 2.6e-05 23.0 0.0 4.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EIW80474.1 - 4.9e-05 23.6 0.0 0.00012 22.3 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 EIW80474.1 - 5.6e-05 22.8 0.4 0.0001 22.0 0.3 1.4 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EIW80474.1 - 0.0016 17.7 0.1 0.0023 17.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.15 EIW80474.1 - 0.024 14.5 0.1 0.046 13.6 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus OCD_Mu_crystall PF02423.10 EIW80474.1 - 0.1 11.3 0.2 0.16 10.7 0.2 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family BatA PF07584.6 EIW80475.1 - 1.9 8.7 9.9 3.2 8.0 0.1 3.5 3 0 0 3 3 3 0 Aerotolerance regulator N-terminal Peptidase_S24 PF00717.18 EIW80476.1 - 1.5e-08 34.1 0.0 2.6e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like SR-25 PF10500.4 EIW80477.1 - 0.0047 16.4 66.3 0.0047 16.4 46.0 2.3 1 1 1 2 2 2 1 Nuclear RNA-splicing-associated protein MIP-T3 PF10243.4 EIW80477.1 - 2.6 6.4 42.0 3.8 5.8 29.1 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 E1-E2_ATPase PF00122.15 EIW80478.1 - 5.6e-77 257.8 0.1 1.1e-76 256.9 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EIW80478.1 - 3.8e-37 127.5 0.4 8.3e-37 126.4 0.3 1.6 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EIW80478.1 - 5.7e-31 108.6 0.0 1.7e-30 107.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIW80478.1 - 3e-15 56.9 0.0 1e-14 55.1 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIW80478.1 - 5.5e-15 55.0 0.0 1.8e-14 53.4 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EIW80478.1 - 1.9e-12 46.4 0.0 4.1e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIW80478.1 - 8.8e-05 22.1 1.8 0.001 18.7 0.4 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RseC_MucC PF04246.7 EIW80478.1 - 0.0027 17.2 2.4 0.0034 16.9 0.0 2.4 2 0 0 2 2 2 1 Positive regulator of sigma(E), RseC/MucC Shisa PF13908.1 EIW80480.1 - 0.0024 18.0 1.5 0.0053 16.9 1.1 1.6 1 1 0 1 1 1 1 Wnt and FGF inhibitory regulator Senescence_reg PF04520.8 EIW80480.1 - 5.5 7.4 7.0 2.4 8.6 1.7 2.0 1 1 1 2 2 2 0 Senescence regulator 3HCDH PF00725.17 EIW80481.1 - 1e-06 29.0 0.0 1.1e-06 28.9 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain zf-C2H2 PF00096.21 EIW80482.1 - 8.4e-08 32.1 5.7 9e-05 22.5 0.6 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW80482.1 - 1.8e-05 24.8 11.2 0.0063 16.7 0.1 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EIW80482.1 - 0.0007 19.6 2.2 0.04 14.0 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EIW80482.1 - 0.003 17.7 3.2 1.2 9.5 0.3 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EIW80482.1 - 0.17 12.1 5.2 5.3 7.3 0.1 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type 3HCDH_N PF02737.13 EIW80483.1 - 5.3e-48 163.0 4.1 6.8e-47 159.4 2.8 2.4 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EIW80483.1 - 5.1e-32 110.1 0.0 1.6e-31 108.5 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EIW80483.1 - 0.00066 19.5 1.7 0.0013 18.6 0.7 1.8 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EIW80483.1 - 0.014 15.1 0.2 0.023 14.4 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 EIW80483.1 - 0.055 12.6 0.7 0.47 9.5 0.1 2.1 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EIW80483.1 - 5.8 7.4 6.3 8.9 6.8 1.6 3.0 2 1 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Granulin PF00396.13 EIW80484.1 - 0.071 13.2 28.1 0.83 9.7 1.8 2.9 1 1 2 3 3 3 0 Granulin zf-C2H2 PF00096.21 EIW80485.1 - 3.5e-11 42.7 6.4 1.5e-06 28.2 1.0 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW80485.1 - 3.8e-08 33.2 9.5 0.00042 20.4 0.0 3.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIW80485.1 - 6.8e-07 29.1 5.0 0.00026 21.1 0.7 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EIW80485.1 - 0.0014 18.2 0.2 0.0036 16.9 0.2 1.6 1 0 0 1 1 1 1 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 EIW80485.1 - 0.016 15.3 2.9 0.041 14.0 0.3 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIW80485.1 - 0.041 14.1 0.5 0.041 14.1 0.4 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EIW80485.1 - 0.046 13.8 1.5 0.08 13.0 1.0 1.3 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_2 PF12756.2 EIW80485.1 - 0.18 11.9 1.4 0.37 10.9 0.2 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EIW80486.1 - 4e-11 42.5 3.4 7.8e-05 22.7 0.1 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW80486.1 - 4e-08 33.1 10.3 3.1e-06 27.2 0.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIW80486.1 - 9.5e-08 31.8 2.7 0.0016 18.6 0.1 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EIW80486.1 - 0.00096 19.2 1.6 0.0015 18.6 1.1 1.2 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EIW80486.1 - 0.00099 19.1 0.1 1.5 9.0 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EIW80486.1 - 0.24 11.1 5.2 4.8 7.0 1.4 2.3 2 0 0 2 2 2 0 BED zinc finger zf-C2H2 PF00096.21 EIW80487.1 - 8.4e-12 44.7 7.4 7.7e-06 25.9 0.5 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW80487.1 - 2.2e-10 40.3 8.2 6.5e-07 29.3 0.2 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIW80487.1 - 3.7e-08 33.1 4.3 0.00067 19.8 0.3 2.6 2 1 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIW80487.1 - 0.00049 20.1 0.8 0.0018 18.3 0.1 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EIW80487.1 - 0.0012 18.5 3.8 0.31 10.8 0.8 2.4 1 1 1 2 2 2 2 BED zinc finger zf-C2H2_2 PF12756.2 EIW80487.1 - 0.12 12.4 0.5 0.39 10.8 0.1 1.8 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Sulfate_transp PF00916.15 EIW80488.1 - 2.6e-52 177.5 7.5 2.6e-52 177.5 5.2 1.8 1 1 1 2 2 2 1 Sulfate transporter family STAS PF01740.16 EIW80488.1 - 2e-22 78.8 0.0 3.2e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 STAS domain Sulfate_tra_GLY PF13792.1 EIW80488.1 - 2.5e-22 78.3 7.1 2.5e-22 78.3 4.9 3.6 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS_2 PF13466.1 EIW80488.1 - 1.8e-05 24.6 0.0 4.5e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 STAS domain ILVD_EDD PF00920.16 EIW80489.1 - 4.9e-200 665.3 0.1 5.6e-200 665.1 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family APH PF01636.18 EIW80492.1 - 0.0079 15.9 0.7 0.014 15.1 0.4 1.3 1 1 0 1 1 1 1 Phosphotransferase enzyme family Mito_fiss_reg PF05308.6 EIW80492.1 - 0.063 12.6 1.4 0.082 12.2 1.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF3678 PF12435.3 EIW80492.1 - 2.5 7.7 6.1 5.3 6.6 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) Peptidase_S8 PF00082.17 EIW80493.1 - 6e-53 179.8 5.9 8.8e-53 179.2 4.1 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EIW80493.1 - 8.8e-15 55.0 0.0 1.7e-14 54.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Pro-kuma_activ PF09286.6 EIW80494.1 - 2.2e-41 141.2 0.0 3.5e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain DUF4066 PF13278.1 EIW80495.1 - 2.1e-12 46.6 0.1 4.1e-12 45.6 0.1 1.5 1 1 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EIW80495.1 - 0.13 11.6 0.0 3 7.2 0.0 2.1 2 0 0 2 2 2 0 DJ-1/PfpI family F-box PF00646.28 EIW80497.1 - 1.6e-06 27.6 0.3 4.9e-06 26.0 0.2 1.9 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW80497.1 - 0.001 18.7 1.1 0.0029 17.2 0.8 1.8 1 0 0 1 1 1 1 F-box-like Aldo_ket_red PF00248.16 EIW80498.1 - 1.4e-53 181.6 0.1 1.6e-53 181.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family IKI3 PF04762.7 EIW80500.1 - 7.6e-239 795.1 0.0 6.7e-237 788.6 0.0 2.1 1 1 0 1 1 1 1 IKI3 family RtcB PF01139.12 EIW80500.1 - 0.036 13.0 0.0 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB TPR_12 PF13424.1 EIW80500.1 - 0.22 11.4 2.9 11 6.0 0.7 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat polyprenyl_synt PF00348.12 EIW80501.1 - 1e-44 152.3 0.0 7.6e-22 77.4 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase DUF1981 PF09324.5 EIW80501.1 - 0.024 14.1 0.0 0.049 13.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1981) UDPGP PF01704.13 EIW80502.1 - 2.6e-180 599.4 0.8 3e-180 599.2 0.6 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase MFS_1 PF07690.11 EIW80503.1 - 6.9e-35 120.3 24.7 9.9e-35 119.8 17.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3671 PF12420.3 EIW80503.1 - 1.6 8.7 4.4 7.8 6.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function Glyco_hydro_31 PF01055.21 EIW80508.1 - 7.3e-146 486.4 1.0 7.3e-146 486.4 0.7 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EIW80508.1 - 2.9e-16 59.0 0.0 7.6e-16 57.7 0.0 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like Pro-kuma_activ PF09286.6 EIW80511.1 - 1.3e-43 148.4 0.2 2.9e-43 147.3 0.0 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIW80511.1 - 2.8e-05 23.3 0.8 7.3e-05 22.0 0.6 1.6 1 0 0 1 1 1 1 Subtilase family Pro-kuma_activ PF09286.6 EIW80513.1 - 1.9e-45 154.4 0.7 8.5e-45 152.3 0.1 2.1 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain COX14 PF14880.1 EIW80514.1 - 0.00032 20.2 2.3 0.00045 19.7 1.6 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c assembly adh_short PF00106.20 EIW80515.1 - 8.8e-20 71.2 0.0 1.3e-19 70.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW80515.1 - 2.3e-08 33.9 0.0 3.6e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIW80515.1 - 0.00013 21.9 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EIW80515.1 - 0.0025 17.6 0.1 0.0042 16.8 0.1 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EIW80515.1 - 0.02 14.9 0.1 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EIW80515.1 - 0.023 14.1 0.1 0.038 13.4 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family QRPTase_C PF01729.14 EIW80515.1 - 0.071 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain NmrA PF05368.8 EIW80515.1 - 0.093 11.9 0.1 0.25 10.5 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family 3Beta_HSD PF01073.14 EIW80515.1 - 0.1 11.2 0.0 0.17 10.5 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family SNF2_N PF00176.18 EIW80516.1 - 2e-70 236.9 0.4 3.1e-70 236.3 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW80516.1 - 6.1e-13 48.4 0.1 7.1e-12 45.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW80516.1 - 2.1e-06 27.6 0.0 6.5e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EIW80516.1 - 0.00047 19.6 0.0 0.00091 18.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 EIW80516.1 - 0.0053 15.6 0.0 2.5 6.8 0.0 2.6 2 0 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 Pkinase PF00069.20 EIW80517.1 - 1.5e-69 234.0 0.0 1.7e-69 233.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW80517.1 - 1.9e-37 128.7 0.0 2.4e-37 128.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW80517.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EIW80517.1 - 0.012 14.6 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Homeobox PF00046.24 EIW80518.1 - 2.5e-08 33.3 0.9 5.1e-08 32.4 0.3 1.7 2 0 0 2 2 2 1 Homeobox domain DnaJ PF00226.26 EIW80519.1 - 2.6e-15 55.8 0.0 4.3e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain ER_lumen_recept PF00810.13 EIW80520.1 - 5.8e-59 198.8 10.7 8.2e-59 198.3 7.4 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EIW80520.1 - 0.0011 18.5 6.3 0.34 10.4 0.0 4.0 4 0 0 4 4 4 2 PQ loop repeat DUF2207 PF09972.4 EIW80520.1 - 0.043 12.4 0.8 0.055 12.0 0.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PSI_8 PF00796.13 EIW80520.1 - 0.2 11.2 0.2 0.2 11.2 0.2 2.5 2 0 0 2 2 2 0 Photosystem I reaction centre subunit VIII Lectin_leg-like PF03388.8 EIW80521.1 - 5.5e-65 218.7 0.2 7.1e-65 218.3 0.1 1.1 1 0 0 1 1 1 1 Legume-like lectin family HEAT_EZ PF13513.1 EIW80522.1 - 2.8e-19 69.0 23.3 5.8e-08 33.0 0.0 10.8 9 4 3 12 12 12 4 HEAT-like repeat HEAT_2 PF13646.1 EIW80522.1 - 3.3e-18 65.7 0.4 0.00037 20.7 0.0 7.4 4 4 5 9 9 9 4 HEAT repeats HEAT PF02985.17 EIW80522.1 - 6.6e-18 63.1 13.9 0.00011 21.9 0.0 9.5 9 0 0 9 9 8 4 HEAT repeat Arm PF00514.18 EIW80522.1 - 1.7e-09 37.1 0.3 0.36 10.7 0.0 6.3 5 0 0 5 5 5 3 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 EIW80522.1 - 3.9e-07 30.1 0.5 0.28 11.0 0.0 6.0 4 1 3 7 7 7 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EIW80522.1 - 4.4e-06 26.9 0.0 0.098 13.0 0.0 4.4 4 1 0 4 4 4 2 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 EIW80522.1 - 1.9e-05 24.5 0.1 0.0029 17.4 0.0 3.3 3 0 0 3 3 3 1 Importin-beta N-terminal domain Adaptin_N PF01602.15 EIW80522.1 - 0.0038 15.6 0.1 1.8 6.7 0.0 3.9 4 0 0 4 4 4 1 Adaptin N terminal region Cohesin_HEAT PF12765.2 EIW80522.1 - 0.02 14.8 0.9 71 3.5 0.0 5.0 6 0 0 6 6 6 0 HEAT repeat associated with sister chromatid cohesion DUF3437 PF11919.3 EIW80522.1 - 0.021 14.5 0.0 0.26 11.0 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) RasGEF_N_2 PF14663.1 EIW80522.1 - 0.079 12.8 0.1 1.7 8.6 0.0 3.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Cnd3 PF12719.2 EIW80522.1 - 0.18 10.7 1.1 1.7 7.5 0.0 3.0 4 0 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain Lysine_decarbox PF03641.9 EIW80523.1 - 1.6e-27 95.9 0.0 2.2e-27 95.4 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase KdpA PF03814.10 EIW80525.1 - 0.076 11.0 0.0 0.094 10.7 0.0 1.1 1 0 0 1 1 1 0 Potassium-transporting ATPase A subunit DUF4203 PF13886.1 EIW80526.1 - 0.0004 19.9 23.2 0.0015 17.9 16.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4203) F-box-like PF12937.2 EIW80527.1 - 2.1e-05 24.1 1.4 5.2e-05 22.8 1.0 1.7 1 0 0 1 1 1 1 F-box-like GST_N PF02798.15 EIW80528.1 - 1.7e-12 47.3 0.0 3.3e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW80528.1 - 4.7e-11 42.5 0.0 8.2e-11 41.7 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIW80528.1 - 3e-07 30.5 0.0 4.7e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW80528.1 - 4.1e-06 26.5 0.0 7.1e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW80528.1 - 2e-05 24.9 0.0 3.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW80528.1 - 0.00036 20.4 0.0 0.00078 19.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DUF3387 PF11867.3 EIW80528.1 - 0.16 10.9 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) Zn_clus PF00172.13 EIW80530.1 - 0.00018 21.3 8.9 0.00028 20.7 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_2 PF07716.10 EIW80531.1 - 6.1e-08 32.3 11.5 6.7e-07 29.0 7.0 2.1 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 EIW80531.1 - 1.5e-07 31.2 11.7 9.1e-07 28.7 8.1 1.9 1 1 0 1 1 1 1 bZIP transcription factor DUF2205 PF10224.4 EIW80531.1 - 0.00075 19.0 0.6 0.00098 18.6 0.4 1.2 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) bZIP_Maf PF03131.12 EIW80531.1 - 0.0021 18.3 3.8 0.0032 17.7 2.6 1.2 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF2216 PF10226.4 EIW80531.1 - 0.0028 17.1 0.6 0.0028 17.1 0.4 1.1 1 0 0 1 1 1 1 Uncharacterized conserved proteins (DUF2216) KLRAQ PF10205.4 EIW80531.1 - 0.057 13.4 0.9 0.071 13.1 0.6 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein TSC22 PF01166.13 EIW80531.1 - 0.1 12.5 0.9 0.2 11.6 0.5 1.6 1 1 0 1 1 1 0 TSC-22/dip/bun family DUF972 PF06156.8 EIW80531.1 - 0.15 12.4 0.4 0.17 12.2 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) IncA PF04156.9 EIW80531.1 - 0.34 10.4 1.4 0.38 10.3 1.0 1.1 1 0 0 1 1 1 0 IncA protein Shugoshin_N PF07558.6 EIW80531.1 - 3 7.6 6.7 0.28 10.9 0.6 2.0 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region Asp PF00026.18 EIW80534.1 - 0.019 14.1 0.0 0.023 13.9 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic aspartyl protease Mito_carr PF00153.22 EIW80537.1 - 1.4e-67 223.4 3.2 8.3e-22 76.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein FSH1 PF03959.8 EIW80538.1 - 1.1e-52 178.5 0.0 1.4e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EIW80538.1 - 1.4e-05 24.9 0.0 2.2e-05 24.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW80538.1 - 1.8e-05 24.7 0.3 0.057 13.2 0.0 2.3 1 1 0 2 2 2 2 Alpha/beta hydrolase family Calpain_III PF01067.17 EIW80539.1 - 1.7e-19 69.8 0.1 2.4e-09 36.9 0.0 4.1 3 1 0 4 4 4 3 Calpain large subunit, domain III Peptidase_C2 PF00648.16 EIW80539.1 - 3.7e-15 55.7 0.0 5.4e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease MIT PF04212.13 EIW80539.1 - 5.2e-05 23.0 3.7 9.6e-05 22.1 2.6 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain p450 PF00067.17 EIW80542.1 - 7.6e-34 117.0 0.0 6.2e-32 110.7 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EIW80543.1 - 0.0023 17.6 0.2 0.0051 16.5 0.0 1.7 2 0 0 2 2 2 1 F-box-like Kri1 PF05178.7 EIW80545.1 - 8.8e-24 83.7 2.8 8.8e-24 83.7 1.9 6.0 4 2 0 4 4 4 1 KRI1-like family Kri1_C PF12936.2 EIW80545.1 - 2.4e-22 78.6 0.0 2.4e-22 78.6 0.0 4.8 5 0 0 5 5 5 1 KRI1-like family C-terminal GHMP_kinases_C PF08544.8 EIW80546.1 - 3 8.1 6.9 1.1 9.4 2.5 1.9 2 0 0 2 2 2 0 GHMP kinases C terminal F-box-like PF12937.2 EIW80547.1 - 1.2e-08 34.5 3.3 7.1e-08 32.0 2.3 2.3 1 1 0 1 1 1 1 F-box-like OPT PF03169.10 EIW80549.1 - 1.3e-188 628.3 45.7 1.5e-188 628.1 31.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Pantoate_ligase PF02569.10 EIW80550.1 - 1.1e-75 254.0 0.0 3.4e-75 252.4 0.0 1.7 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase AAA PF00004.24 EIW80551.1 - 4.7e-15 55.9 0.0 5e-14 52.6 0.0 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 EIW80551.1 - 0.00076 18.4 0.0 0.0013 17.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EIW80551.1 - 0.00078 19.4 0.0 0.0019 18.1 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 EIW80551.1 - 0.0038 16.3 0.0 0.0069 15.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 EIW80551.1 - 0.006 17.3 0.1 0.012 16.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EIW80551.1 - 0.0091 15.0 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_24 PF13479.1 EIW80551.1 - 0.015 14.9 0.3 0.037 13.6 0.1 1.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EIW80551.1 - 0.04 14.2 0.0 0.1 12.9 0.0 1.6 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.17 EIW80551.1 - 0.059 13.5 0.0 0.51 10.5 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.1 EIW80551.1 - 0.059 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EIW80551.1 - 0.062 12.6 0.0 0.15 11.4 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EIW80551.1 - 0.078 12.6 0.1 0.25 11.0 0.0 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) Miro PF08477.8 EIW80551.1 - 0.092 13.2 0.0 0.25 11.8 0.0 1.7 2 0 0 2 2 2 0 Miro-like protein Arch_ATPase PF01637.13 EIW80551.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 EIW80551.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain TIP49 PF06068.8 EIW80551.1 - 0.22 10.1 0.0 0.31 9.7 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus LSM PF01423.17 EIW80552.1 - 3.9e-15 55.1 0.0 5.1e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF4098 PF13345.1 EIW80553.1 - 0.0019 18.0 2.8 0.0035 17.2 0.2 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4098) DUF2140 PF09911.4 EIW80553.1 - 0.18 11.0 0.0 0.3 10.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) F-box-like PF12937.2 EIW80554.1 - 5.7e-05 22.7 0.0 0.00023 20.8 0.0 2.1 1 1 0 1 1 1 1 F-box-like SnoaL_2 PF12680.2 EIW80555.1 - 0.069 13.5 0.0 0.091 13.1 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like domain GST_N PF02798.15 EIW80557.1 - 1.3e-09 38.1 0.0 2e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EIW80557.1 - 4.2e-09 36.4 0.0 7.1e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW80557.1 - 2.7e-08 33.6 0.0 4.7e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIW80557.1 - 4.2e-08 32.9 0.0 7.6e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW80557.1 - 3.1e-05 24.3 0.1 7.4e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW80557.1 - 0.0019 18.1 0.0 0.0045 16.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain F-box PF00646.28 EIW80558.1 - 0.00075 19.0 0.2 0.00075 19.0 0.1 2.8 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 EIW80558.1 - 0.0099 15.5 0.1 0.0099 15.5 0.0 2.7 3 0 0 3 3 3 1 F-box-like tRNA-synt_2 PF00152.15 EIW80559.1 - 2.6e-73 246.7 0.0 3.9e-73 246.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EIW80559.1 - 1.3e-10 40.9 0.0 4.2e-10 39.3 0.0 1.8 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain DegS PF05384.6 EIW80559.1 - 0.023 13.9 3.5 0.11 11.6 2.4 2.0 2 0 0 2 2 2 0 Sensor protein DegS AUX_IAA PF02309.11 EIW80559.1 - 0.039 13.6 1.6 0.065 12.9 1.1 1.2 1 0 0 1 1 1 0 AUX/IAA family Smac_DIABLO PF09057.5 EIW80559.1 - 1.4 7.9 5.7 2.7 7.0 4.0 1.3 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases Sec62 PF03839.11 EIW80559.1 - 1.9 7.8 8.1 3.3 7.0 5.6 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 adh_short PF00106.20 EIW80560.1 - 1.1e-13 51.4 0.1 1.9e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW80560.1 - 3.2e-05 23.6 0.1 8.2e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 KR domain TP_methylase PF00590.15 EIW80561.1 - 4.4e-19 69.0 0.1 7.8e-19 68.2 0.0 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases p450 PF00067.17 EIW80562.1 - 6.2e-67 226.1 0.0 7.9e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3152 PF11350.3 EIW80563.1 - 0.071 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3152) p450 PF00067.17 EIW80564.1 - 3.2e-14 52.2 0.0 3.6e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW80565.1 - 9.3e-52 176.0 0.0 1.2e-51 175.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EIW80566.1 - 6.2e-09 35.4 0.2 3e-08 33.2 0.0 2.3 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 EIW80567.1 - 3.3e-07 29.9 2.2 7e-07 28.8 0.2 2.6 2 1 0 2 2 2 1 F-box-like F-box-like PF12937.2 EIW80568.1 - 1.7e-05 24.4 0.1 3.9e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIW80568.1 - 0.13 11.9 2.1 1.3 8.6 0.1 3.5 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) Evr1_Alr PF04777.8 EIW80569.1 - 5.9e-29 99.8 0.2 8.2e-29 99.3 0.1 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Pantoate_transf PF02548.10 EIW80570.1 - 3.8e-101 337.6 0.5 4.6e-101 337.3 0.3 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EIW80570.1 - 1.9e-07 30.5 0.1 3.9e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Pyr_redox_3 PF13738.1 EIW80574.1 - 2.1e-21 76.9 0.0 3.1e-20 73.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIW80574.1 - 4.4e-20 71.3 0.0 5.1e-19 67.8 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EIW80574.1 - 1.1e-17 64.5 0.0 1.1e-09 38.4 0.0 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW80574.1 - 5.7e-12 45.2 0.0 1.4e-08 34.0 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EIW80574.1 - 3.3e-06 26.9 0.0 0.021 14.6 0.0 2.8 2 1 0 2 2 2 2 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EIW80574.1 - 8.8e-06 25.8 0.1 0.005 16.9 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.16 EIW80574.1 - 2.3e-05 24.0 1.3 0.1 12.1 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 EIW80574.1 - 3.2e-05 23.1 0.0 0.00012 21.2 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EIW80574.1 - 3.4e-05 24.1 2.8 0.0051 17.1 0.1 3.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EIW80574.1 - 5.1e-05 23.4 0.0 0.074 13.3 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding NAD_binding_8 PF13450.1 EIW80574.1 - 6.8e-05 22.8 0.0 0.00024 21.0 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EIW80574.1 - 0.00066 18.2 2.9 0.0013 17.3 0.1 2.6 3 0 0 3 3 3 1 HI0933-like protein GIDA PF01134.17 EIW80574.1 - 0.0022 16.9 0.6 0.39 9.5 0.0 2.9 4 0 0 4 4 4 1 Glucose inhibited division protein A DAO PF01266.19 EIW80574.1 - 0.0023 16.8 2.2 0.25 10.2 0.0 2.8 3 1 1 4 4 4 2 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EIW80574.1 - 0.0031 16.6 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EIW80574.1 - 0.0035 16.4 0.1 0.0071 15.4 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIW80574.1 - 0.0087 15.0 0.0 0.13 11.1 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EIW80574.1 - 0.011 14.6 3.2 0.013 14.4 0.3 2.3 2 1 0 2 2 2 0 FAD binding domain NUDIX PF00293.23 EIW80574.1 - 0.026 14.1 0.0 0.056 13.0 0.0 1.5 1 0 0 1 1 1 0 NUDIX domain Thi4 PF01946.12 EIW80574.1 - 0.041 12.9 0.1 0.19 10.8 0.0 2.0 2 0 0 2 2 2 0 Thi4 family 3HCDH_N PF02737.13 EIW80574.1 - 0.19 11.3 0.9 13 5.4 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Arf PF00025.16 EIW80575.1 - 1.7e-12 46.9 0.0 2.3e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF411 PF04214.8 EIW80575.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF F-box-like PF12937.2 EIW80576.1 - 0.0015 18.1 0.1 0.0046 16.6 0.0 1.9 2 0 0 2 2 2 1 F-box-like Abhydrolase_3 PF07859.8 EIW80577.1 - 1e-56 191.8 0.0 1.3e-56 191.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIW80577.1 - 1.8e-05 23.5 0.0 2.4e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EIW80577.1 - 2.7e-05 23.0 0.1 8.2e-05 21.5 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase2 PF12740.2 EIW80577.1 - 0.0036 16.2 0.0 0.0049 15.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.2 EIW80577.1 - 0.01 15.5 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIW80577.1 - 0.039 13.1 0.1 0.11 11.6 0.1 1.8 1 1 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.15 EIW80577.1 - 0.05 13.0 0.3 1.5 8.2 0.2 2.1 1 1 0 1 1 1 0 Putative esterase ERM PF00769.14 EIW80578.1 - 0.0029 17.1 1.6 0.0047 16.4 1.1 1.4 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Atg14 PF10186.4 EIW80578.1 - 1.7 7.5 9.5 3 6.7 6.6 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Striatin PF08232.7 EIW80578.1 - 2.3 8.5 8.1 4.1 7.7 5.6 1.4 1 0 0 1 1 1 0 Striatin family IncA PF04156.9 EIW80578.1 - 4.3 6.8 12.5 2.3 7.7 6.7 2.0 3 0 0 3 3 3 0 IncA protein DivIC PF04977.10 EIW80578.1 - 5.6 6.5 10.6 1.2 8.6 0.7 2.5 1 1 1 2 2 2 0 Septum formation initiator FGGY_C PF02782.11 EIW80579.1 - 0.037 13.6 0.0 1.5 8.4 0.0 2.3 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain HSP70 PF00012.15 EIW80580.1 - 0.00079 17.4 0.0 0.0026 15.7 0.0 1.8 2 0 0 2 2 2 1 Hsp70 protein FGGY_C PF02782.11 EIW80580.1 - 0.11 12.0 0.0 0.98 9.0 0.0 2.1 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain DUF1876 PF08962.6 EIW80581.1 - 0.015 15.0 0.0 0.038 13.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1876) DUF1875 PF08961.5 EIW80582.1 - 0.04 13.2 0.1 0.04 13.2 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1875) IncA PF04156.9 EIW80582.1 - 2.4 7.7 7.1 4.5 6.8 4.9 1.5 1 0 0 1 1 1 0 IncA protein UPF0075 PF03702.9 EIW80583.1 - 0.14 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) Peptidase_M22 PF00814.20 EIW80583.1 - 0.15 11.5 0.0 0.24 10.8 0.0 1.2 1 0 0 1 1 1 0 Glycoprotease family Metal_hydrol PF10118.4 EIW80585.1 - 0.0098 15.3 0.1 0.016 14.6 0.1 1.3 1 0 0 1 1 1 1 Predicted metal-dependent hydrolase GST_N PF02798.15 EIW80586.1 - 1.9e-17 63.1 0.0 3.2e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EIW80586.1 - 3.7e-17 62.3 0.0 8.4e-17 61.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW80586.1 - 1.4e-16 60.2 0.0 2.2e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW80586.1 - 1.2e-13 50.7 0.0 2.8e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW80586.1 - 1.3e-08 34.6 0.1 2e-08 33.9 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW80586.1 - 0.00011 22.6 0.0 0.00013 22.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Ank_2 PF12796.2 EIW80589.1 - 5.4e-14 52.3 0.0 4.2e-08 33.4 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EIW80589.1 - 2.8e-09 36.2 0.2 0.012 15.8 0.0 3.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EIW80589.1 - 2.5e-07 30.7 3.7 0.0023 18.1 0.2 3.9 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIW80589.1 - 3.2e-07 30.6 0.2 0.029 14.8 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EIW80589.1 - 3.9e-06 26.4 1.0 0.011 15.5 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Abhydrolase_3 PF07859.8 EIW80590.1 - 0.062 12.8 0.1 0.38 10.2 0.1 1.9 1 1 0 1 1 1 0 alpha/beta hydrolase fold IncA PF04156.9 EIW80591.1 - 0.0069 16.0 6.1 0.91 9.0 6.1 2.4 2 1 0 2 2 2 1 IncA protein Atg14 PF10186.4 EIW80591.1 - 4.6 6.0 8.5 7.6 5.3 5.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DivIC PF04977.10 EIW80591.1 - 9 5.8 7.7 7.6 6.1 0.2 2.4 1 1 1 2 2 2 0 Septum formation initiator Toxin_10 PF05431.6 EIW80592.1 - 0.011 15.3 0.9 0.24 11.0 0.7 2.3 2 0 0 2 2 2 0 Insecticidal Crystal Toxin, P42 AA_permease_2 PF13520.1 EIW80593.1 - 7.7e-38 130.1 49.7 4.6e-25 88.0 21.7 2.1 1 1 1 2 2 2 2 Amino acid permease AA_permease PF00324.16 EIW80593.1 - 3.2e-09 35.6 43.9 9.5e-05 20.9 21.3 2.2 1 1 1 2 2 2 2 Amino acid permease Herpes_US9 PF06072.6 EIW80593.1 - 0.23 11.3 0.0 0.23 11.3 0.0 3.9 5 0 0 5 5 5 0 Alphaherpesvirus tegument protein US9 AA_permease_2 PF13520.1 EIW80594.1 - 1.9e-57 194.7 51.7 2.3e-57 194.4 35.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIW80594.1 - 5.9e-15 54.5 46.1 8.9e-15 53.9 32.0 1.2 1 0 0 1 1 1 1 Amino acid permease F-box-like PF12937.2 EIW80595.1 - 3e-05 23.6 0.0 0.00012 21.7 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIW80596.1 - 6.9e-09 35.2 1.0 2.2e-08 33.6 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIW80596.1 - 0.038 13.6 1.9 0.41 10.3 0.0 3.0 3 0 0 3 3 3 0 F-box domain Glyco_hydro_31 PF01055.21 EIW80599.1 - 5.6e-12 45.2 0.0 6e-12 45.1 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 p450 PF00067.17 EIW80605.1 - 1.7e-61 208.1 0.0 2.2e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Reticulon PF02453.12 EIW80605.1 - 0.025 14.2 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 Reticulon FAD_binding_3 PF01494.14 EIW80606.1 - 4.8e-74 249.5 0.0 6.1e-74 249.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EIW80606.1 - 3.1e-05 24.3 0.1 0.17 12.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW80606.1 - 0.0003 19.9 0.0 0.00067 18.8 0.0 1.5 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.9 EIW80606.1 - 0.0008 19.3 0.0 0.0072 16.2 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW80606.1 - 0.00082 19.3 0.0 0.0054 16.7 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIW80606.1 - 0.00095 19.2 0.0 0.0033 17.5 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW80606.1 - 0.001 18.0 0.0 0.17 10.7 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EIW80606.1 - 0.0036 15.8 0.1 0.04 12.4 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EIW80606.1 - 0.0039 16.0 0.1 0.026 13.3 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EIW80606.1 - 0.016 14.3 0.2 0.054 12.5 0.1 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase zf-C2H2 PF00096.21 EIW80607.1 - 6.6e-05 23.0 9.8 0.0047 17.1 0.0 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW80607.1 - 0.00032 20.8 0.2 0.00032 20.8 0.1 3.3 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIW80607.1 - 0.013 15.8 8.3 0.73 10.2 2.5 3.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EIW80607.1 - 0.15 12.3 9.8 0.045 13.9 1.5 3.3 3 0 0 3 3 3 0 C2H2-type zinc-finger domain GAGA PF09237.6 EIW80607.1 - 0.4 10.3 2.8 0.41 10.2 0.4 2.1 1 1 1 2 2 2 0 GAGA factor KR PF08659.5 EIW80608.1 - 1.4e-07 31.3 0.0 3e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EIW80608.1 - 1.4e-06 28.3 0.0 3.9e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase Cpn60_TCP1 PF00118.19 EIW80609.1 - 7.8e-136 453.5 0.3 8.9e-136 453.3 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nitro_FeMo-Co PF02579.12 EIW80609.1 - 0.058 13.4 0.0 0.2 11.7 0.0 1.9 1 0 0 1 1 1 0 Dinitrogenase iron-molybdenum cofactor RhoGAP PF00620.22 EIW80610.1 - 2.2e-42 144.2 0.0 4.6e-42 143.1 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain RasGEF PF00617.14 EIW80610.1 - 3.7e-11 43.1 0.0 2.5e-06 27.3 0.0 2.6 2 0 0 2 2 2 2 RasGEF domain PH_9 PF15410.1 EIW80610.1 - 3.5e-06 27.1 0.1 3.1e-05 24.0 0.1 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EIW80610.1 - 5e-06 26.6 0.0 9.9e-05 22.4 0.0 2.4 2 0 0 2 2 2 1 PH domain RasGEF_N PF00618.15 EIW80610.1 - 8.2e-06 25.8 0.0 8.7e-05 22.5 0.0 2.9 3 1 0 3 3 3 1 RasGEF N-terminal motif F-box-like PF12937.2 EIW80612.1 - 8.9e-10 38.1 0.5 3.2e-09 36.3 0.4 2.1 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW80612.1 - 0.19 11.4 2.3 1.7 8.3 0.1 3.1 3 0 0 3 3 3 0 F-box domain AA_permease_2 PF13520.1 EIW80613.1 - 5.8e-51 173.3 52.7 7e-51 173.1 36.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIW80613.1 - 4.7e-14 51.6 47.5 6.9e-14 51.0 32.9 1.2 1 0 0 1 1 1 1 Amino acid permease Herpes_US9 PF06072.6 EIW80613.1 - 1.8 8.4 0.0 1.8 8.4 0.0 4.3 5 0 0 5 5 5 0 Alphaherpesvirus tegument protein US9 HSP70 PF00012.15 EIW80615.1 - 0.026 12.4 0.1 0.22 9.3 0.0 2.4 2 0 0 2 2 2 0 Hsp70 protein ADH_zinc_N PF00107.21 EIW80617.1 - 5.7e-28 97.0 0.9 8.8e-28 96.4 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW80617.1 - 2.2e-18 67.3 0.2 4e-18 66.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW80617.1 - 2.3e-11 43.4 0.0 4.3e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain DUF3481 PF11980.3 EIW80618.1 - 0.029 14.1 1.1 0.11 12.3 0.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3481) MFS_1 PF07690.11 EIW80619.1 - 8.2e-34 116.8 27.3 8.2e-34 116.8 18.9 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Oxidored_q2 PF00420.19 EIW80619.1 - 0.0097 15.4 3.2 0.03 13.8 0.1 3.0 2 2 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L CopD PF05425.8 EIW80619.1 - 0.014 15.6 1.6 0.028 14.6 0.0 2.4 2 1 0 2 2 2 0 Copper resistance protein D DUF4244 PF14029.1 EIW80619.1 - 7.2 5.7 6.2 0.69 9.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4244) F-box-like PF12937.2 EIW80621.1 - 2.6e-19 68.6 9.3 1.6e-12 46.9 0.3 3.2 3 0 0 3 3 3 2 F-box-like F-box PF00646.28 EIW80621.1 - 0.0015 18.1 0.3 0.0015 18.1 0.2 3.2 3 0 0 3 3 3 1 F-box domain F-box-like_2 PF13013.1 EIW80621.1 - 0.12 12.1 0.1 0.12 12.1 0.0 2.5 3 0 0 3 3 3 0 F-box-like domain LEA_3 PF03242.8 EIW80621.1 - 0.27 11.4 0.4 23 5.3 0.0 2.6 2 0 0 2 2 2 0 Late embryogenesis abundant protein MFS_1 PF07690.11 EIW80623.1 - 2.7e-05 23.0 27.7 0.0018 17.0 13.1 3.5 2 1 1 3 3 3 3 Major Facilitator Superfamily AAA_16 PF13191.1 EIW80624.1 - 6.8e-05 22.9 0.0 7.4e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EIW80624.1 - 0.00059 19.5 0.0 0.00078 19.1 0.0 1.2 1 1 0 1 1 1 1 NACHT domain APS_kinase PF01583.15 EIW80624.1 - 0.0022 17.6 0.0 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.1 EIW80624.1 - 0.02 15.1 0.0 0.022 15.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EIW80624.1 - 0.035 14.2 0.0 0.039 14.0 0.0 1.2 1 1 0 1 1 1 0 AAA domain Cytidylate_kin2 PF13189.1 EIW80624.1 - 0.047 13.5 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family PRK PF00485.13 EIW80624.1 - 0.05 13.1 0.0 0.13 11.7 0.0 1.6 1 1 1 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EIW80624.1 - 0.075 13.8 0.1 0.11 13.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EIW80624.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Acetyltransf_1 PF00583.19 EIW80625.1 - 2.3e-07 30.7 0.0 4.2e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EIW80625.1 - 0.00083 19.2 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIW80625.1 - 0.005 16.5 0.0 0.0089 15.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EIW80625.1 - 0.027 14.6 0.0 0.038 14.1 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIW80625.1 - 0.03 14.2 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Cyclin_N PF00134.18 EIW80626.1 - 1.3e-10 40.9 0.0 1.9e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EIW80626.1 - 3.3e-09 37.3 0.0 6e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Cyclin AAA_16 PF13191.1 EIW80628.1 - 2.8e-07 30.6 1.9 1.9e-06 28.0 0.0 3.0 3 1 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 EIW80628.1 - 0.0013 18.2 0.0 0.0031 16.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.24 EIW80628.1 - 0.0039 17.4 0.3 0.021 15.0 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIW80628.1 - 0.0096 16.0 0.0 0.038 14.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EIW80628.1 - 0.014 15.1 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 EIW80628.1 - 0.015 15.5 0.0 0.036 14.3 0.0 1.8 1 1 0 1 1 1 0 ABC transporter AAA_25 PF13481.1 EIW80628.1 - 0.041 13.2 0.7 0.11 11.8 0.0 2.3 3 1 0 3 3 3 0 AAA domain AAA_14 PF13173.1 EIW80628.1 - 0.064 13.1 0.0 0.32 10.8 0.0 2.2 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 EIW80628.1 - 0.07 12.0 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.1 EIW80628.1 - 0.084 12.7 0.0 0.29 11.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EIW80628.1 - 7.6 7.3 8.3 3.8e+02 1.8 5.8 3.3 1 1 0 1 1 1 0 AAA domain DUF1240 PF06836.7 EIW80631.1 - 1 9.6 8.3 0.18 12.0 1.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1240) E1-E2_ATPase PF00122.15 EIW80633.1 - 0.86 8.5 4.6 3.9 6.4 3.2 1.9 1 1 0 1 1 1 0 E1-E2 ATPase CPSase_L_D2 PF02786.12 EIW80636.1 - 2e-104 347.4 0.0 5.1e-82 274.2 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EIW80636.1 - 3e-42 143.2 0.1 5.4e-42 142.4 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EIW80636.1 - 7.9e-36 123.5 0.4 1.2e-18 67.5 0.3 2.6 2 0 0 2 2 2 2 ATP-grasp domain CPSase_L_chain PF00289.17 EIW80636.1 - 5.9e-34 116.4 0.0 6.3e-18 64.8 0.0 2.7 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 EIW80636.1 - 3.1e-23 82.0 0.0 1.9e-10 39.9 0.0 3.8 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EIW80636.1 - 1e-16 60.7 0.0 3e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EIW80636.1 - 8.1e-13 48.2 0.0 2.2e-05 23.9 0.0 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EIW80636.1 - 1.4e-07 31.1 0.0 0.0014 18.1 0.0 2.9 3 0 0 3 3 3 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EIW80636.1 - 9.6e-06 25.5 0.0 0.0028 17.5 0.0 2.5 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_5 PF13549.1 EIW80636.1 - 0.00012 21.4 0.1 0.05 12.8 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_M17_N PF02789.12 EIW80636.1 - 0.013 15.2 0.0 0.058 13.1 0.0 2.1 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain GARS_A PF01071.14 EIW80636.1 - 0.023 14.2 0.0 1.9 7.9 0.0 2.6 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF106 PF01956.11 EIW80637.1 - 0.16 11.4 1.8 0.16 11.4 0.5 1.5 1 1 0 1 1 1 0 Integral membrane protein DUF106 GST_C PF00043.20 EIW80638.1 - 1.3e-12 47.5 0.0 2e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIW80638.1 - 6e-08 32.8 0.0 1.5e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW80638.1 - 2.6e-06 27.2 0.0 5.4e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW80638.1 - 7.1e-06 26.1 0.0 0.00014 21.9 0.0 2.5 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW80638.1 - 0.00025 20.9 0.0 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIW80638.1 - 0.0098 16.3 0.0 0.017 15.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain CBM_5_12_2 PF14600.1 EIW80638.1 - 0.029 13.9 0.1 0.093 12.3 0.0 1.9 2 0 0 2 2 2 0 Cellulose-binding domain DUF1912 PF08930.5 EIW80638.1 - 0.057 13.5 0.0 0.092 12.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) Glyco_transf_49 PF13896.1 EIW80639.1 - 3.9e-36 124.7 0.0 2.4e-27 95.8 0.0 2.0 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 EIW80639.1 - 0.043 12.9 0.1 1.6 7.7 0.0 2.7 3 0 0 3 3 3 0 Glycosyltransferase like family 2 Abhydrolase_6 PF12697.2 EIW80640.1 - 1.3e-23 84.1 4.1 2e-23 83.4 2.9 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW80640.1 - 5.7e-13 48.8 0.0 2.6e-12 46.7 0.0 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIW80640.1 - 4.6e-08 32.8 0.1 2e-07 30.7 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Ser_hydrolase PF06821.8 EIW80640.1 - 0.0008 19.0 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_1 PF00561.15 EIW80640.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Na_H_Exchanger PF00999.16 EIW80642.1 - 2.5e-62 210.6 47.2 3.4e-62 210.1 32.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family AAA_16 PF13191.1 EIW80644.1 - 4e-09 36.7 0.1 5e-09 36.4 0.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EIW80644.1 - 1.2e-06 28.2 0.0 1.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 NACHT domain APS_kinase PF01583.15 EIW80644.1 - 6.3e-06 25.9 0.1 1.3e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.1 EIW80644.1 - 1.1e-05 25.6 0.0 1.9e-05 24.8 0.0 1.5 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIW80644.1 - 5.4e-05 23.3 0.0 8.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 EIW80644.1 - 0.00011 22.4 0.0 0.00017 21.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.10 EIW80644.1 - 0.00016 20.4 0.0 0.00018 20.3 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein PRK PF00485.13 EIW80644.1 - 0.00027 20.5 0.0 0.00034 20.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family DUF258 PF03193.11 EIW80644.1 - 0.00037 19.7 0.0 0.0004 19.6 0.0 1.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EIW80644.1 - 0.00037 20.8 0.0 0.0004 20.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_17 PF13207.1 EIW80644.1 - 0.00057 20.6 0.1 0.00086 20.1 0.1 1.5 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EIW80644.1 - 0.00061 19.5 0.0 0.00065 19.4 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase NTPase_1 PF03266.10 EIW80644.1 - 0.0011 18.7 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 NTPase NB-ARC PF00931.17 EIW80644.1 - 0.0044 15.9 0.0 0.005 15.7 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_14 PF13173.1 EIW80644.1 - 0.0047 16.8 0.0 0.0059 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW80644.1 - 0.0049 16.6 0.0 0.0071 16.0 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA PF00004.24 EIW80644.1 - 0.0056 16.8 0.0 0.011 15.9 0.0 1.4 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EIW80644.1 - 0.0071 16.0 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EIW80644.1 - 0.0083 14.9 0.0 0.01 14.6 0.0 1.1 1 0 0 1 1 1 1 ArgK protein AAA_5 PF07728.9 EIW80644.1 - 0.0083 15.8 0.1 0.019 14.6 0.0 1.6 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EIW80644.1 - 0.0086 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF2075 PF09848.4 EIW80644.1 - 0.0092 14.9 0.0 0.01 14.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 EIW80644.1 - 0.0099 15.3 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EIW80644.1 - 0.011 14.5 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.7 EIW80644.1 - 0.016 14.3 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin Torsin PF06309.6 EIW80644.1 - 0.017 14.9 0.0 0.023 14.5 0.0 1.4 1 1 0 1 1 1 0 Torsin SKI PF01202.17 EIW80644.1 - 0.021 14.6 0.1 0.035 13.9 0.0 1.5 2 0 0 2 2 1 0 Shikimate kinase AAA_33 PF13671.1 EIW80644.1 - 0.025 14.4 0.1 0.053 13.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain CbiA PF01656.18 EIW80644.1 - 0.027 13.8 0.1 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EIW80644.1 - 0.029 14.2 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EIW80644.1 - 0.03 13.2 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DAP3 PF10236.4 EIW80644.1 - 0.032 13.1 0.0 0.041 12.7 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Cytidylate_kin2 PF13189.1 EIW80644.1 - 0.033 14.1 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family UPF0079 PF02367.12 EIW80644.1 - 0.038 13.6 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF815 PF05673.8 EIW80644.1 - 0.04 12.8 0.0 0.052 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 EIW80644.1 - 0.045 13.1 0.0 0.054 12.9 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 EIW80644.1 - 0.061 13.3 0.0 0.076 13.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 EIW80644.1 - 0.068 12.7 0.0 0.086 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EIW80644.1 - 0.07 12.3 0.0 0.082 12.1 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein AAA_25 PF13481.1 EIW80644.1 - 0.081 12.3 0.0 0.098 12.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 EIW80644.1 - 0.098 12.0 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase Viral_helicase1 PF01443.13 EIW80644.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_10 PF12846.2 EIW80644.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.3 1 1 0 1 1 1 0 AAA-like domain PIF1 PF05970.9 EIW80644.1 - 0.13 11.1 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase KTI12 PF08433.5 EIW80644.1 - 0.14 11.3 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 F-box-like PF12937.2 EIW80645.1 - 1.5e-05 24.6 1.4 4e-05 23.2 0.9 1.8 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.11 EIW80646.1 - 3.6e-30 104.8 24.2 3.6e-30 104.8 16.7 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1664 PF07889.7 EIW80646.1 - 0.0065 16.2 0.1 0.016 15.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) PSDC PF12588.3 EIW80648.1 - 1.2e-42 144.8 0.0 1.8e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 EIW80648.1 - 9.2e-39 132.8 0.0 1.2e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase RnfC_N PF13375.1 EIW80648.1 - 0.016 14.8 0.0 0.37 10.5 0.0 2.6 3 0 0 3 3 3 0 RnfC Barrel sandwich hybrid domain Biotin_lipoyl_2 PF13533.1 EIW80648.1 - 0.046 13.3 0.7 1.3 8.7 0.1 2.3 2 0 0 2 2 2 0 Biotin-lipoyl like Biotin_lipoyl PF00364.17 EIW80648.1 - 0.13 11.9 0.1 0.44 10.2 0.0 1.9 2 0 0 2 2 2 0 Biotin-requiring enzyme Peptidase_M23 PF01551.17 EIW80648.1 - 0.14 12.2 0.0 0.36 10.9 0.0 1.6 1 0 0 1 1 1 0 Peptidase family M23 DUF4231 PF14015.1 EIW80649.1 - 0.48 10.4 4.5 5.1 7.1 0.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) Abhydrolase_6 PF12697.2 EIW80650.1 - 4.3e-27 95.4 0.0 5e-27 95.2 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW80650.1 - 3.5e-14 52.9 0.1 1.2e-13 51.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW80650.1 - 1e-08 35.0 0.0 6.7e-08 32.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EIW80650.1 - 6.8e-06 25.7 0.0 1.9e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PGAP1 PF07819.8 EIW80650.1 - 0.0078 15.8 0.1 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 EIW80650.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain 5_nucleotid PF05761.9 EIW80651.1 - 1.4 7.3 3.1 2.1 6.7 2.1 1.1 1 0 0 1 1 1 0 5' nucleotidase family HALZ PF02183.13 EIW80652.1 - 1.3e-12 47.2 62.7 0.31 10.8 0.1 14.1 13 1 1 14 14 13 6 Homeobox associated leucine zipper CALCOCO1 PF07888.6 EIW80652.1 - 8e-09 34.3 62.7 0.0002 19.8 7.9 5.0 2 2 2 4 4 4 4 Calcium binding and coiled-coil domain (CALCOCO1) like Myosin_tail_1 PF01576.14 EIW80652.1 - 1.5e-06 26.2 77.1 0.00034 18.5 7.3 3.8 2 2 2 4 4 4 3 Myosin tail DUF2353 PF09789.4 EIW80652.1 - 4e-06 26.3 65.2 0.2 10.8 8.2 7.6 1 1 5 7 7 7 5 Uncharacterized coiled-coil protein (DUF2353) HOOK PF05622.7 EIW80652.1 - 1.8e-05 22.8 70.9 0.015 13.1 0.7 5.6 2 2 1 3 3 3 3 HOOK protein Tropomyosin_1 PF12718.2 EIW80652.1 - 8e-05 22.5 78.5 0.06 13.2 6.7 7.0 5 2 1 7 7 6 5 Tropomyosin like Reo_sigmaC PF04582.7 EIW80652.1 - 0.0021 17.3 40.3 0.13 11.4 0.1 6.9 2 2 3 7 7 7 1 Reovirus sigma C capsid protein IncA PF04156.9 EIW80652.1 - 0.0026 17.3 74.9 0.049 13.2 0.9 7.5 2 2 4 7 7 7 2 IncA protein IFT57 PF10498.4 EIW80652.1 - 0.0029 16.4 5.1 0.0029 16.4 3.5 5.2 3 2 2 6 6 6 1 Intra-flagellar transport protein 57 bZIP_1 PF00170.16 EIW80652.1 - 0.0033 17.3 63.4 0.068 13.1 1.3 13.7 9 3 7 16 16 16 2 bZIP transcription factor GAS PF13851.1 EIW80652.1 - 0.0066 15.6 60.2 0.13 11.4 6.5 8.5 3 2 5 9 9 9 4 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 EIW80652.1 - 0.018 15.3 58.2 0.81 10.0 0.9 10.7 2 2 9 12 12 12 0 Protein of unknown function (DUF972) CENP-F_leu_zip PF10473.4 EIW80652.1 - 0.16 11.8 70.0 0.14 12.0 1.5 8.6 3 2 5 9 9 9 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 EIW80652.1 - 0.71 9.6 78.2 1.1 8.9 9.0 7.1 2 2 5 7 7 7 0 Autophagy protein 16 (ATG16) Cast PF10174.4 EIW80652.1 - 0.8 7.6 67.2 0.01 13.9 6.5 4.6 2 2 1 3 3 3 0 RIM-binding protein of the cytomatrix active zone ERM PF00769.14 EIW80652.1 - 0.89 9.0 63.1 0.79 9.2 0.4 7.0 1 1 2 5 5 5 0 Ezrin/radixin/moesin family CCDC155 PF14662.1 EIW80652.1 - 1.2 8.6 74.2 0.069 12.7 2.0 7.2 2 2 4 6 6 6 0 Coiled-coil region of CCDC155 RasGAP_C PF03836.10 EIW80652.1 - 1.5 8.4 29.9 0.67 9.6 0.5 5.7 3 2 3 6 6 6 0 RasGAP C-terminus DUF869 PF05911.6 EIW80652.1 - 2.2 6.4 54.1 3.3 5.8 16.1 4.0 2 2 1 3 3 3 0 Plant protein of unknown function (DUF869) DUF904 PF06005.7 EIW80652.1 - 2.9 8.2 68.4 1.7 8.9 0.6 12.2 7 2 1 8 8 6 0 Protein of unknown function (DUF904) STAT_alpha PF01017.15 EIW80652.1 - 5.4 6.6 35.6 0.73 9.5 0.3 5.9 3 2 3 6 6 6 0 STAT protein, all-alpha domain MAD PF05557.8 EIW80652.1 - 6.3 4.7 64.9 0.077 11.0 6.0 6.0 2 2 1 4 4 4 0 Mitotic checkpoint protein Bacillus_HBL PF05791.6 EIW80652.1 - 8.5 5.6 34.7 3.7 6.8 0.2 8.1 6 3 2 9 9 9 0 Bacillus haemolytic enterotoxin (HBL) MbeD_MobD PF04899.7 EIW80652.1 - 9.8 6.1 39.1 2.5 8.0 0.6 10.0 7 5 4 11 11 11 0 MbeD/MobD like Aldo_ket_red PF00248.16 EIW80654.1 - 8.1e-73 244.6 0.1 9.2e-73 244.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF4185 PF13810.1 EIW80655.1 - 0.00037 19.4 0.1 0.00087 18.2 0.1 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4185) ATE_C PF04377.10 EIW80655.1 - 0.019 15.0 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Arginine-tRNA-protein transferase, C terminus DUF1793 PF08760.6 EIW80656.1 - 1.1e-54 184.8 0.8 2.8e-54 183.5 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Glyco_hydro_28 PF00295.12 EIW80657.1 - 1e-60 205.4 22.4 1.4e-60 205.0 15.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EIW80657.1 - 9.6e-06 25.4 36.7 2.6e-05 24.0 20.1 3.2 1 1 1 2 2 2 2 Right handed beta helix region DUF1565 PF07602.6 EIW80657.1 - 0.00026 20.2 9.4 0.00026 20.2 6.5 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF1565) GST_N PF02798.15 EIW80658.1 - 1.4e-17 63.6 0.0 3.5e-17 62.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EIW80658.1 - 5.7e-14 52.1 0.0 1e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW80658.1 - 1.7e-10 40.7 0.0 2.8e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW80658.1 - 1.8e-09 37.4 0.0 3.6e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW80658.1 - 2e-06 27.6 0.1 3.4e-06 26.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW80658.1 - 0.0047 17.3 0.0 0.0072 16.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain MetRS-N PF09635.5 EIW80658.1 - 0.088 13.1 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 MetRS-N binding domain HALZ PF02183.13 EIW80659.1 - 0.0031 17.2 9.9 0.32 10.7 0.6 3.0 2 2 0 2 2 2 2 Homeobox associated leucine zipper RHD3 PF05879.7 EIW80659.1 - 0.028 12.3 2.5 0.038 11.9 1.8 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) DUF904 PF06005.7 EIW80659.1 - 0.33 11.2 10.2 0.36 11.1 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF904) FadA PF09403.5 EIW80659.1 - 0.58 10.1 6.4 0.08 12.9 0.7 2.1 1 1 0 2 2 2 0 Adhesion protein FadA Striatin PF08232.7 EIW80659.1 - 0.81 10.0 6.3 1.9 8.8 0.2 2.5 2 0 0 2 2 2 0 Striatin family DUF1515 PF07439.6 EIW80659.1 - 1.1 9.0 7.1 4 7.3 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) DUF2361 PF10153.4 EIW80659.1 - 2 8.6 7.7 8.3 6.6 0.5 2.8 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2361) ADIP PF11559.3 EIW80659.1 - 3.6 7.4 10.3 2.3 8.1 1.1 2.5 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding PEP-utilisers_N PF05524.8 EIW80659.1 - 4.4 7.1 11.4 0.86 9.4 2.3 2.7 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal bZIP_1 PF00170.16 EIW80659.1 - 7.2 6.6 9.7 1 9.4 1.5 2.9 3 0 0 3 3 3 0 bZIP transcription factor TPR_MLP1_2 PF07926.7 EIW80659.1 - 10 5.9 11.6 86 2.8 8.1 2.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein GST_C PF00043.20 EIW80660.1 - 0.031 14.2 0.2 0.2 11.6 0.1 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Inositol_P PF00459.20 EIW80660.1 - 0.083 12.1 0.0 0.083 12.1 0.0 1.1 1 0 0 1 1 1 0 Inositol monophosphatase family MIF4G PF02854.14 EIW80662.1 - 9.4e-11 41.5 0.0 1e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 MIF4G domain TauD PF02668.11 EIW80663.1 - 1.3e-48 165.9 0.3 1.7e-48 165.5 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fungal_trans PF04082.13 EIW80664.1 - 5.9e-09 35.1 0.0 8e-09 34.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ODV-E18 PF10717.4 EIW80665.1 - 0.061 12.7 2.1 0.13 11.7 1.4 1.4 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Glyco_trans_4_4 PF13579.1 EIW80666.1 - 0.0013 18.9 0.7 0.0018 18.4 0.5 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain NFRKB_winged PF14465.1 EIW80666.1 - 0.024 14.4 0.1 0.038 13.8 0.1 1.4 1 0 0 1 1 1 0 NFRKB Winged Helix-like DUF1818 PF08848.6 EIW80666.1 - 0.083 12.9 0.1 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1818) bZIP_1 PF00170.16 EIW80666.1 - 0.77 9.7 3.0 10 6.1 0.2 2.3 1 1 1 2 2 2 0 bZIP transcription factor Filament PF00038.16 EIW80667.1 - 0.00014 21.4 2.9 0.00017 21.1 2.0 1.1 1 0 0 1 1 1 1 Intermediate filament protein Myosin_tail_1 PF01576.14 EIW80667.1 - 0.00094 17.0 3.9 0.0011 16.8 2.7 1.0 1 0 0 1 1 1 1 Myosin tail WEMBL PF05701.6 EIW80667.1 - 0.0014 17.2 2.5 0.0016 16.9 1.7 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light IncA PF04156.9 EIW80667.1 - 0.0018 17.9 1.0 0.0022 17.6 0.7 1.3 1 0 0 1 1 1 1 IncA protein Peripla_BP_2 PF01497.13 EIW80667.1 - 0.015 14.4 0.1 0.018 14.1 0.1 1.1 1 0 0 1 1 1 0 Periplasmic binding protein GAS PF13851.1 EIW80667.1 - 0.016 14.3 0.3 0.019 14.1 0.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Fez1 PF06818.10 EIW80667.1 - 0.018 15.0 3.3 0.022 14.7 2.3 1.2 1 0 0 1 1 1 0 Fez1 Spc7 PF08317.6 EIW80667.1 - 0.022 13.4 0.6 0.025 13.2 0.4 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.6 EIW80667.1 - 0.022 14.5 2.2 0.026 14.3 1.6 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Rab5-bind PF09311.6 EIW80667.1 - 0.03 14.2 3.1 0.042 13.7 2.1 1.2 1 0 0 1 1 1 0 Rabaptin-like protein Tropomyosin_1 PF12718.2 EIW80667.1 - 0.032 14.0 2.2 0.045 13.6 1.6 1.2 1 0 0 1 1 1 0 Tropomyosin like CENP-F_leu_zip PF10473.4 EIW80667.1 - 0.033 14.0 1.5 0.041 13.7 1.0 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MscS_porin PF12795.2 EIW80667.1 - 0.033 13.5 2.3 0.041 13.1 1.6 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Tropomyosin PF00261.15 EIW80667.1 - 0.035 13.1 5.0 0.31 10.0 2.0 1.9 1 1 1 2 2 2 0 Tropomyosin DUF2730 PF10805.3 EIW80667.1 - 0.04 13.6 0.3 0.26 11.0 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) DUF1640 PF07798.6 EIW80667.1 - 0.043 13.8 0.5 0.053 13.5 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Sec8_exocyst PF04048.9 EIW80667.1 - 0.12 12.0 1.0 1.1 8.8 0.1 2.0 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain DUF3498 PF12004.3 EIW80667.1 - 0.17 11.0 3.9 0.19 10.8 2.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) YscO PF07321.7 EIW80667.1 - 0.24 11.1 8.2 0.61 9.9 5.7 1.6 1 1 0 1 1 1 0 Type III secretion protein YscO PEP-utilisers_N PF05524.8 EIW80667.1 - 1.3 8.8 4.7 10 5.9 0.8 2.1 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal 7TMR-HDED PF07697.6 EIW80668.1 - 0.021 14.5 0.1 0.1 12.2 0.1 2.0 1 1 0 1 1 1 0 7TM-HD extracellular Syntaxin-6_N PF09177.6 EIW80668.1 - 0.19 12.1 1.3 8.8 6.8 0.2 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Cortex-I_coil PF09304.5 EIW80668.1 - 0.37 10.8 3.1 12 6.0 1.0 2.2 1 1 1 2 2 2 0 Cortexillin I, coiled coil TMF_TATA_bd PF12325.3 EIW80668.1 - 0.71 9.6 3.3 3.4 7.4 2.3 1.9 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 EIW80668.1 - 4 6.9 8.0 12 5.4 5.5 1.9 1 1 0 1 1 1 0 IncA protein MbeD_MobD PF04899.7 EIW80669.1 - 0.028 14.3 3.9 0.033 14.0 0.1 3.0 3 0 0 3 3 3 0 MbeD/MobD like FAD_binding_3 PF01494.14 EIW80670.1 - 5.6e-54 183.5 0.2 1.1e-52 179.2 0.2 2.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIW80670.1 - 2e-07 30.2 0.6 0.0038 16.1 0.4 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW80670.1 - 0.00014 22.1 0.4 0.18 12.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW80670.1 - 0.01 15.9 0.2 5.3 7.0 0.3 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIW80670.1 - 0.015 14.3 1.3 0.091 11.8 0.9 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW80670.1 - 0.019 14.9 1.1 0.044 13.8 0.3 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIW80670.1 - 0.027 14.3 0.4 0.096 12.5 0.2 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW80670.1 - 0.049 12.0 1.2 1.5 7.2 0.4 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 EIW80670.1 - 0.23 10.2 5.2 1.5 7.6 0.8 2.6 3 0 0 3 3 3 0 FAD binding domain RNase_T PF00929.19 EIW80671.1 - 1.5e-19 70.8 0.0 2.1e-19 70.3 0.0 1.2 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EIW80671.1 - 0.00032 20.2 0.0 0.00062 19.2 0.0 1.4 1 1 0 1 1 1 1 3'-5' exonuclease FNIP_N PF14636.1 EIW80671.1 - 0.11 12.9 0.3 0.11 12.9 0.2 1.8 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus Mito_carr PF00153.22 EIW80672.1 - 3.5e-60 199.7 2.9 4.5e-20 71.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Colicin_V PF02674.11 EIW80672.1 - 0.18 11.6 7.2 3.1 7.6 0.1 3.1 3 0 0 3 3 3 0 Colicin V production protein HSP70 PF00012.15 EIW80673.1 - 0.00046 18.2 0.0 0.0011 17.0 0.0 1.5 2 0 0 2 2 2 1 Hsp70 protein HSP70 PF00012.15 EIW80674.1 - 0.027 12.3 0.0 1.3 6.8 0.1 2.7 3 0 0 3 3 3 0 Hsp70 protein HSP70 PF00012.15 EIW80675.1 - 0.093 10.6 0.0 1.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Hsp70 protein Atg14 PF10186.4 EIW80676.1 - 0.097 11.6 0.4 0.14 11.0 0.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 OPA3 PF07047.7 EIW80676.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) RNA_polI_A34 PF08208.6 EIW80680.1 - 0.86 9.2 13.4 1.3 8.6 9.3 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 OrfB_Zn_ribbon PF07282.6 EIW80680.1 - 3.9 7.2 9.4 0.66 9.6 3.4 2.0 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Zn_clus PF00172.13 EIW80680.1 - 8.8 6.3 17.2 57 3.7 11.9 2.3 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Tet_JBP PF12851.2 EIW80682.1 - 3.2e-13 49.3 0.0 4.1e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Spc42p PF11544.3 EIW80686.1 - 0.019 14.8 0.3 0.41 10.5 0.1 2.5 2 0 0 2 2 2 0 Spindle pole body component Spc42p HMG_box_2 PF09011.5 EIW80687.1 - 0.00029 21.1 1.9 0.00029 21.1 1.3 2.0 2 0 0 2 2 2 1 HMG-box domain HMG_box PF00505.14 EIW80687.1 - 0.016 15.4 0.9 0.053 13.8 0.6 1.9 1 0 0 1 1 1 0 HMG (high mobility group) box AF-4 PF05110.8 EIW80689.1 - 3.6 5.3 2.9 5.3 4.7 2.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DEAD PF00270.24 EIW80690.1 - 5.7e-08 32.4 0.0 1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW80690.1 - 3.4e-05 23.6 0.0 0.00012 21.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PK_C PF02887.11 EIW80690.1 - 0.049 13.1 0.3 0.6 9.6 0.1 2.6 2 1 1 3 3 3 0 Pyruvate kinase, alpha/beta domain RNase_T PF00929.19 EIW80691.1 - 6.2e-30 104.6 0.0 7.9e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Exonuclease Polysacc_deac_1 PF01522.16 EIW80692.1 - 2.3e-21 75.6 0.0 6.2e-21 74.2 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide deacetylase F-box-like PF12937.2 EIW80694.1 - 2.1e-08 33.7 0.5 5.2e-08 32.4 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW80694.1 - 5e-05 22.8 0.4 0.00021 20.8 0.2 2.1 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.2 EIW80694.1 - 0.69 9.6 4.2 4.6 6.9 0.1 3.6 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) GST_N_3 PF13417.1 EIW80695.1 - 2.9e-15 56.2 0.0 5.2e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW80695.1 - 2.4e-14 53.2 0.0 4.2e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW80695.1 - 6.5e-14 51.6 0.0 1e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIW80695.1 - 2.1e-07 30.7 0.0 4.8e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW80695.1 - 2.5e-07 30.5 0.0 4.1e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIW80695.1 - 0.00014 22.2 0.0 0.00017 21.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1912 PF08930.5 EIW80695.1 - 0.06 13.4 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) MetRS-N PF09635.5 EIW80695.1 - 0.11 12.9 0.1 0.62 10.4 0.0 2.1 2 1 0 2 2 2 0 MetRS-N binding domain HSP70 PF00012.15 EIW80696.1 - 3.2e-05 22.0 0.0 0.0011 16.9 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein SAP PF02037.22 EIW80697.1 - 0.00014 21.2 0.0 0.0019 17.6 0.0 2.2 2 0 0 2 2 2 1 SAP domain Ank_4 PF13637.1 EIW80697.1 - 0.0015 18.9 3.0 19 5.9 0.1 4.6 3 2 2 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIW80697.1 - 0.016 15.5 0.0 9.5 6.6 0.0 3.0 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EIW80697.1 - 0.14 12.4 0.4 1.5e+02 3.1 0.0 4.4 5 0 0 5 5 5 0 Ankyrin repeat DUF1917 PF08939.5 EIW80701.1 - 3.6e-24 85.8 0.5 3.6e-24 85.8 0.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1917) FKBP_N PF01346.13 EIW80701.1 - 0.049 13.6 0.8 0.049 13.6 0.6 2.8 2 1 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase DUF3936 PF13072.1 EIW80701.1 - 0.24 10.9 1.1 8.5 5.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3936) Fcf1 PF04900.7 EIW80702.1 - 2.8e-40 136.4 0.8 2.8e-40 136.4 0.5 1.6 2 0 0 2 2 2 1 Fcf1 Gar1 PF04410.9 EIW80703.1 - 0.0023 17.3 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region DUF98 PF01947.11 EIW80703.1 - 0.13 12.0 0.0 0.2 11.3 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF98) Lyase_aromatic PF00221.14 EIW80706.1 - 5.7e-142 473.4 3.6 9.2e-142 472.8 2.5 1.3 1 0 0 1 1 1 1 Aromatic amino acid lyase GST_N PF02798.15 EIW80708.1 - 4.7e-15 55.5 0.0 2.1e-14 53.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EIW80708.1 - 2.1e-13 50.2 0.0 6.2e-13 48.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW80708.1 - 1.1e-10 41.3 0.0 2.1e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW80708.1 - 2e-06 27.7 0.0 3.4e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW80708.1 - 0.0059 16.4 0.1 0.022 14.6 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW80708.1 - 0.0077 16.6 0.0 0.012 16.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1912 PF08930.5 EIW80708.1 - 0.011 15.8 0.1 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1912) MFS_1 PF07690.11 EIW80709.1 - 5.1e-35 120.8 33.7 5.1e-35 120.8 23.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW80709.1 - 2.9e-12 45.9 9.7 2.9e-12 45.9 6.7 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter PEX11 PF05648.9 EIW80710.1 - 0.11 11.7 0.0 0.22 10.7 0.0 1.5 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) AAA_16 PF13191.1 EIW80711.1 - 1.6e-07 31.4 0.0 2.3e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EIW80711.1 - 2.4e-06 27.3 0.0 3.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 NACHT domain APS_kinase PF01583.15 EIW80711.1 - 8.9e-06 25.4 0.0 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.1 EIW80711.1 - 1e-05 25.6 0.0 2.7e-05 24.3 0.0 1.6 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIW80711.1 - 0.00015 21.8 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 EIW80711.1 - 0.00026 21.3 0.0 0.00037 20.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIW80711.1 - 0.00053 20.3 0.0 0.00068 19.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter NTPase_1 PF03266.10 EIW80711.1 - 0.00061 19.5 0.0 0.001 18.7 0.0 1.4 2 0 0 2 2 1 1 NTPase AAA_17 PF13207.1 EIW80711.1 - 0.00068 20.4 0.0 0.00095 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain PRK PF00485.13 EIW80711.1 - 0.0009 18.8 0.0 0.002 17.7 0.0 1.6 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family MobB PF03205.9 EIW80711.1 - 0.00098 18.8 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EIW80711.1 - 0.0014 17.5 0.0 0.0018 17.2 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain AAA_29 PF13555.1 EIW80711.1 - 0.0016 17.9 0.0 0.0028 17.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EIW80711.1 - 0.0021 17.8 0.0 0.0024 17.6 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase Zeta_toxin PF06414.7 EIW80711.1 - 0.0021 17.1 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin T2SE PF00437.15 EIW80711.1 - 0.0026 16.6 0.0 0.0031 16.4 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF258 PF03193.11 EIW80711.1 - 0.0031 16.7 0.0 0.0038 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Sigma54_activat PF00158.21 EIW80711.1 - 0.0063 16.0 0.0 0.0088 15.5 0.0 1.2 1 0 0 1 1 1 1 Sigma-54 interaction domain DUF2075 PF09848.4 EIW80711.1 - 0.0071 15.3 0.0 0.0085 15.1 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Cytidylate_kin2 PF13189.1 EIW80711.1 - 0.0092 15.9 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 1 Cytidylate kinase-like family Thymidylate_kin PF02223.12 EIW80711.1 - 0.0099 15.2 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Thymidylate kinase CbiA PF01656.18 EIW80711.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.1 EIW80711.1 - 0.012 15.4 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EIW80711.1 - 0.013 14.2 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 ArgK protein AAA_30 PF13604.1 EIW80711.1 - 0.016 14.7 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EIW80711.1 - 0.018 15.1 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.1 EIW80711.1 - 0.021 14.5 0.0 0.038 13.7 0.0 1.5 1 1 0 1 1 1 0 Part of AAA domain SLIDE PF09111.5 EIW80711.1 - 0.025 14.3 0.0 0.99 9.1 0.0 2.1 1 1 1 2 2 2 0 SLIDE KTI12 PF08433.5 EIW80711.1 - 0.025 13.8 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 UPF0079 PF02367.12 EIW80711.1 - 0.025 14.2 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 TrwB_AAD_bind PF10412.4 EIW80711.1 - 0.026 13.1 0.0 0.035 12.7 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_10 PF12846.2 EIW80711.1 - 0.031 13.7 0.0 0.042 13.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 EIW80711.1 - 0.033 14.0 0.0 0.048 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain PIF1 PF05970.9 EIW80711.1 - 0.038 12.9 0.0 0.044 12.7 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase FtsK_SpoIIIE PF01580.13 EIW80711.1 - 0.064 12.7 0.0 0.084 12.3 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_31 PF13614.1 EIW80711.1 - 0.073 12.9 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EIW80711.1 - 0.08 12.6 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Torsin PF06309.6 EIW80711.1 - 0.1 12.5 0.0 0.17 11.7 0.0 1.5 1 1 0 1 1 1 0 Torsin AAA_23 PF13476.1 EIW80711.1 - 0.11 12.8 0.0 0.16 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EIW80711.1 - 0.12 10.9 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DAO PF01266.19 EIW80713.1 - 4.6e-52 177.0 0.0 5.7e-52 176.7 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIW80713.1 - 1.1e-10 41.8 0.0 1.1e-08 35.4 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EIW80713.1 - 1.2e-06 27.8 0.1 0.00085 18.5 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EIW80713.1 - 1.5e-06 28.1 0.0 4.9e-06 26.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EIW80713.1 - 2.2e-06 27.5 0.2 0.045 13.5 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EIW80713.1 - 5e-06 25.6 0.1 0.093 11.5 0.0 2.9 3 0 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.9 EIW80713.1 - 9.1e-06 25.6 0.0 0.066 13.0 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW80713.1 - 4e-05 23.9 0.0 0.004 17.5 0.0 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW80713.1 - 6.6e-05 21.5 0.0 0.055 11.9 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.14 EIW80713.1 - 0.00026 20.1 0.0 0.00077 18.6 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EIW80713.1 - 0.0007 18.5 0.0 0.078 11.8 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Shikimate_DH PF01488.15 EIW80713.1 - 0.0021 18.1 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 EIW80713.1 - 0.022 14.6 0.0 0.06 13.2 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase ThiF PF00899.16 EIW80713.1 - 0.023 14.5 0.0 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.7 EIW80713.1 - 0.029 13.3 0.0 3.7 6.3 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 EIW80713.1 - 0.03 14.5 0.0 0.079 13.2 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding FAD_oxidored PF12831.2 EIW80713.1 - 0.065 12.3 0.0 0.29 10.1 0.0 1.8 1 1 0 1 1 1 0 FAD dependent oxidoreductase Peptidase_A17 PF05380.8 EIW80714.1 - 0.029 14.2 0.2 0.043 13.6 0.1 1.4 1 1 0 1 1 1 0 Pao retrotransposon peptidase Peptidase_S49 PF01343.13 EIW80714.1 - 0.079 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Peptidase family S49 Sel1 PF08238.7 EIW80715.1 - 2.3e-18 66.2 51.8 7.1e-06 26.4 0.1 9.9 10 1 0 10 10 10 6 Sel1 repeat TPR_16 PF13432.1 EIW80715.1 - 0.0015 19.1 7.6 0.0092 16.6 0.5 7.2 6 2 1 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIW80715.1 - 0.1 13.0 11.8 6.5 7.4 0.6 5.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIW80715.1 - 0.31 10.7 16.7 0.06 13.0 0.5 4.1 5 1 1 6 6 6 0 TPR repeat TPR_1 PF00515.23 EIW80715.1 - 7.9 6.2 14.7 0.31 10.7 0.6 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SWIB PF02201.13 EIW80716.1 - 1.5e-23 82.2 0.1 2.2e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 SWIB/MDM2 domain DEK_C PF08766.6 EIW80716.1 - 0.043 13.6 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 DEK C terminal domain Nop14 PF04147.7 EIW80716.1 - 0.71 7.7 11.5 1.1 7.1 8.0 1.2 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.7 EIW80716.1 - 2.1 8.1 8.1 3.5 7.4 5.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RVT_1 PF00078.22 EIW80719.1 - 1.1e-07 31.4 0.0 1.2e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIW80720.1 - 0.00089 19.5 0.5 0.0029 17.8 0.2 1.9 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase PPTA PF01239.17 EIW80721.1 - 7e-07 28.3 0.7 0.05 12.9 0.0 4.2 4 0 0 4 4 4 2 Protein prenyltransferase alpha subunit repeat Mito_carr PF00153.22 EIW80723.1 - 5.1e-16 58.1 0.0 2.9e-07 30.1 0.0 2.8 3 1 0 3 3 3 2 Mitochondrial carrier protein DUF4341 PF14241.1 EIW80723.1 - 0.026 14.2 0.1 0.077 12.7 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4341) Mito_carr PF00153.22 EIW80724.1 - 0.0002 20.9 0.0 0.4 10.4 0.0 2.7 2 1 0 2 2 2 2 Mitochondrial carrier protein Pkinase PF00069.20 EIW80725.1 - 2.8e-39 134.8 0.0 4.3e-39 134.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW80725.1 - 1.2e-35 122.8 0.0 1.8e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW80725.1 - 1.7e-05 24.6 0.1 5.7e-05 22.9 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW80725.1 - 2e-05 23.7 0.0 3.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EIW80725.1 - 0.17 11.2 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Patatin PF01734.17 EIW80726.1 - 8.6e-22 78.0 0.1 1.3e-21 77.4 0.1 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Pkinase_Tyr PF07714.12 EIW80727.1 - 1.5e-45 155.2 0.0 2e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EIW80727.1 - 8.4e-45 152.9 0.0 1.1e-44 152.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EIW80727.1 - 6.2e-07 28.6 0.0 9.7e-07 28.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW80727.1 - 0.018 14.7 0.1 0.041 13.6 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family BcrAD_BadFG PF01869.15 EIW80728.1 - 1.3e-09 37.7 0.6 1.5e-08 34.2 0.2 2.4 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family FGGY_N PF00370.16 EIW80728.1 - 0.071 12.4 0.1 0.22 10.8 0.0 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain 2-Hacid_dh_C PF02826.14 EIW80730.1 - 4.7e-51 172.4 0.0 6.5e-51 171.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIW80730.1 - 2e-15 56.4 0.0 2.4e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EIW80730.1 - 0.015 15.1 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_N PF08240.7 EIW80731.1 - 4.3e-14 52.1 0.0 9.3e-14 51.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW80731.1 - 4.9e-09 35.8 0.0 9.5e-09 34.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EIW80733.1 - 3.6e-14 52.4 1.2 6.6e-14 51.5 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW80733.1 - 4.7e-12 45.6 0.1 8.6e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIW80733.1 - 7.4e-06 26.8 0.0 1.5e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sel1 PF08238.7 EIW80736.1 - 4.2e-05 24.0 5.7 0.0081 16.7 0.2 4.7 5 0 0 5 5 5 1 Sel1 repeat TPR_11 PF13414.1 EIW80736.1 - 0.019 14.5 2.9 1.8 8.2 0.2 3.5 3 1 1 4 4 4 0 TPR repeat TPR_1 PF00515.23 EIW80736.1 - 0.082 12.5 2.1 4 7.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIW80736.1 - 0.19 12.4 11.8 3.3 8.5 0.0 4.5 3 3 1 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIW80736.1 - 0.28 11.7 0.0 0.28 11.7 0.0 3.7 3 2 1 4 4 4 0 Tetratricopeptide repeat PH PF00169.24 EIW80738.1 - 1.6e-06 28.2 0.0 3.3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 PH domain Glucosamine_iso PF01182.15 EIW80739.1 - 1.4e-23 83.6 0.0 2.5e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Beta-lactamase PF00144.19 EIW80740.1 - 1.7e-45 155.5 0.1 5.2e-45 153.9 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase Pyr_redox_3 PF13738.1 EIW80741.1 - 3.7e-20 72.8 0.0 5.9e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW80741.1 - 2.3e-09 36.6 0.0 6.9e-09 35.0 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EIW80741.1 - 4.1e-09 35.1 0.0 7.3e-09 34.3 0.0 1.3 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EIW80741.1 - 7.8e-07 29.0 0.0 8.5e-05 22.4 0.0 2.9 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIW80741.1 - 0.0018 18.6 0.1 2.4 8.6 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIW80741.1 - 0.017 14.2 0.0 0.057 12.4 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EIW80741.1 - 0.023 13.8 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DAO PF01266.19 EIW80741.1 - 0.027 13.4 0.7 0.12 11.1 0.1 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.12 EIW80741.1 - 0.032 13.3 0.1 0.1 11.6 0.0 1.8 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 EIW80741.1 - 0.062 12.1 0.0 0.13 11.1 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 EIW80741.1 - 0.062 13.0 0.2 0.5 10.1 0.0 2.5 2 1 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EIW80741.1 - 0.063 13.1 0.1 2.9 7.7 0.1 2.8 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DcpS_C PF11969.3 EIW80742.1 - 2.5e-24 85.7 0.0 4.1e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 EIW80742.1 - 3.1e-23 82.2 0.0 4.8e-23 81.6 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal p450 PF00067.17 EIW80743.1 - 1.7e-72 244.4 0.0 2.3e-72 244.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 EIW80747.1 - 4e-31 108.0 0.0 7e-31 107.2 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EIW80747.1 - 2.6e-05 24.7 0.0 7.5e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW80747.1 - 0.00023 21.6 0.0 0.00056 20.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW80747.1 - 0.00024 20.8 0.0 0.00037 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW80747.1 - 0.0037 16.8 0.0 0.012 15.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EIW80747.1 - 0.024 14.0 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.11 EIW80747.1 - 0.11 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_11 PF08241.7 EIW80747.1 - 0.13 12.7 0.0 0.65 10.5 0.0 2.2 3 0 0 3 3 3 0 Methyltransferase domain Asp PF00026.18 EIW80748.1 - 1.1e-46 159.5 4.9 3.8e-46 157.7 3.4 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW80748.1 - 1.6e-06 28.1 0.6 2.7e-05 24.1 0.3 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIW80748.1 - 0.00062 20.2 0.4 0.00062 20.2 0.2 2.2 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 EIW80748.1 - 0.011 15.3 0.1 0.1 12.1 0.0 2.2 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal HhH-GPD PF00730.20 EIW80749.1 - 7.6e-23 80.8 0.0 2.5e-22 79.2 0.0 1.9 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 EIW80749.1 - 3.4e-10 39.3 0.1 4.4e-08 32.5 0.0 2.8 3 0 0 3 3 3 1 NUDIX domain EndIII_4Fe-2S PF10576.4 EIW80749.1 - 0.011 15.8 9.9 0.032 14.4 6.8 1.9 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III HHH PF00633.18 EIW80749.1 - 0.069 12.8 0.3 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix motif AAA_16 PF13191.1 EIW80750.1 - 6.1e-06 26.3 0.0 6.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.15 EIW80750.1 - 0.00049 19.7 0.0 0.00072 19.2 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.17 EIW80750.1 - 0.00084 19.4 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 EIW80750.1 - 0.00092 19.3 0.1 0.0026 17.8 0.0 1.7 1 1 1 2 2 2 1 AAA domain NACHT PF05729.7 EIW80750.1 - 0.0014 18.3 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 NACHT domain MobB PF03205.9 EIW80750.1 - 0.0026 17.4 0.0 0.01 15.5 0.0 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EIW80750.1 - 0.0027 16.8 0.0 0.0033 16.5 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin ABC_tran PF00005.22 EIW80750.1 - 0.003 17.8 0.0 0.0044 17.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EIW80750.1 - 0.0087 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EIW80750.1 - 0.013 14.6 0.0 0.015 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EIW80750.1 - 0.015 14.9 0.0 0.018 14.7 0.0 1.1 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 EIW80750.1 - 0.017 15.9 0.0 0.035 14.9 0.0 1.6 2 0 0 2 2 1 0 AAA domain ResIII PF04851.10 EIW80750.1 - 0.027 14.3 0.0 0.029 14.2 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EIW80750.1 - 0.04 13.3 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 EIW80750.1 - 0.049 13.1 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Sigma54_activat PF00158.21 EIW80750.1 - 0.056 12.9 0.0 0.07 12.6 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain SMC_N PF02463.14 EIW80750.1 - 0.057 12.6 0.0 0.073 12.2 0.0 1.1 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain DUF815 PF05673.8 EIW80750.1 - 0.077 11.9 0.0 0.079 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 EIW80750.1 - 0.082 12.9 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.11 EIW80750.1 - 0.084 12.0 0.0 0.096 11.9 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.12 EIW80750.1 - 0.094 12.1 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.9 EIW80750.1 - 0.094 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EIW80750.1 - 0.097 12.9 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Gp37_Gp68 PF07505.6 EIW80750.1 - 0.098 11.8 0.0 0.098 11.8 0.0 1.1 1 0 0 1 1 1 0 Phage protein Gp37/Gp68 NB-ARC PF00931.17 EIW80750.1 - 0.12 11.2 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 EIW80750.1 - 0.13 11.7 0.1 0.24 10.7 0.1 1.5 1 1 1 2 2 2 0 AAA-like domain Torsin PF06309.6 EIW80750.1 - 0.13 12.0 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Torsin AAA_PrkA PF08298.6 EIW80750.1 - 0.14 10.8 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 PrkA AAA domain BRCT PF00533.21 EIW80751.1 - 3.3e-06 27.1 0.0 5.2e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EIW80751.1 - 0.014 15.2 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 twin BRCT domain p450 PF00067.17 EIW80753.1 - 7.6e-67 225.8 0.0 1.3e-65 221.7 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 DUF3039 PF11238.3 EIW80753.1 - 0.032 13.6 0.0 0.41 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) NAD_kinase PF01513.16 EIW80754.1 - 6.7e-58 195.7 0.0 9.3e-58 195.2 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase PSRT PF07636.6 EIW80755.1 - 0.049 13.0 1.7 0.1 12.0 1.2 1.6 1 0 0 1 1 1 0 PSRT XPG_I_2 PF12813.2 EIW80756.1 - 1e-08 34.9 0.1 6.6e-08 32.3 0.0 2.1 2 0 0 2 2 2 1 XPG domain containing NACHT PF05729.7 EIW80758.1 - 3.7e-10 39.7 0.1 1.4e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EIW80758.1 - 5e-09 36.4 0.4 1.1e-08 35.2 0.3 1.6 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 EIW80758.1 - 0.00047 20.2 0.0 0.00096 19.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 EIW80758.1 - 0.00085 19.4 0.0 0.0022 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EIW80758.1 - 0.0024 17.5 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_18 PF13238.1 EIW80758.1 - 0.0059 16.9 0.0 0.025 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EIW80758.1 - 0.008 16.4 0.0 0.019 15.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter PRK PF00485.13 EIW80758.1 - 0.01 15.3 0.0 0.024 14.1 0.0 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Arch_ATPase PF01637.13 EIW80758.1 - 0.018 14.7 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 EIW80758.1 - 0.025 15.3 0.1 0.099 13.4 0.0 2.1 2 0 0 2 2 1 0 AAA domain Rad17 PF03215.10 EIW80758.1 - 0.033 12.8 0.0 0.056 12.1 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA PF00004.24 EIW80758.1 - 0.048 13.8 0.0 0.099 12.8 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EIW80758.1 - 0.071 12.6 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.10 EIW80758.1 - 0.073 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 NTPase DUF258 PF03193.11 EIW80758.1 - 0.083 12.0 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Sigma54_activ_2 PF14532.1 EIW80758.1 - 0.1 12.6 0.1 0.4 10.7 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 EIW80758.1 - 0.17 10.9 0.0 0.33 9.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 EIW80758.1 - 0.18 11.6 0.0 0.4 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EIW80758.1 - 0.21 11.0 0.0 0.39 10.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain ArgK PF03308.11 EIW80758.1 - 0.29 9.8 0.0 0.47 9.1 0.0 1.2 1 0 0 1 1 1 0 ArgK protein NB-ARC PF00931.17 EIW80758.1 - 0.32 9.8 0.0 0.52 9.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain Cornichon PF03311.9 EIW80759.1 - 1.3e-53 180.5 7.7 1.4e-53 180.4 5.3 1.0 1 0 0 1 1 1 1 Cornichon protein Oxidored_q3 PF00499.15 EIW80759.1 - 5.9 6.6 12.8 13 5.5 8.9 1.5 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF4470 PF14737.1 EIW80760.1 - 1.2e-15 57.0 0.0 2.5e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EIW80760.1 - 5.7e-08 32.5 11.9 1.5e-07 31.1 8.3 1.8 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 EIW80761.1 - 1.9e-10 40.4 11.3 3.8e-10 39.4 7.8 1.5 1 0 0 1 1 1 1 MYND finger DUF4470 PF14737.1 EIW80761.1 - 1.5e-06 27.8 0.0 3.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-HIT PF04438.11 EIW80761.1 - 2.7 7.7 8.1 5.1 6.8 5.6 1.5 1 0 0 1 1 1 0 HIT zinc finger RRM_1 PF00076.17 EIW80762.1 - 1.1e-05 24.9 0.0 1.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW80762.1 - 3.2e-05 23.8 0.0 6.1e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW80762.1 - 0.00061 19.5 0.1 0.0015 18.3 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) API5 PF05918.6 EIW80762.1 - 3.2 6.1 9.7 4.6 5.6 6.7 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) DUF4470 PF14737.1 EIW80764.1 - 4.6e-08 32.7 0.3 9.7e-07 28.4 0.2 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4470) DUF4470 PF14737.1 EIW80765.1 - 4.9e-20 71.1 0.1 5e-19 67.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EIW80765.1 - 1.1e-10 41.1 9.7 1.1e-10 41.1 6.7 2.7 3 0 0 3 3 3 1 MYND finger zf-MYND PF01753.13 EIW80766.1 - 1.3e-10 40.9 11.0 3.2e-10 39.6 7.6 1.7 1 0 0 1 1 1 1 MYND finger DUF4470 PF14737.1 EIW80766.1 - 1.4e-10 40.7 0.0 4.5e-10 39.1 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4470) 2-Hacid_dh_C PF02826.14 EIW80767.1 - 5.9e-46 155.8 0.0 8e-46 155.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIW80767.1 - 8.6e-10 38.1 0.0 1.2e-09 37.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EIW80767.1 - 0.00053 19.8 0.0 0.00099 18.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EIW80767.1 - 0.13 11.5 0.0 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF2263 PF10021.4 EIW80768.1 - 1.1e-22 80.6 0.2 9.2e-22 77.6 0.0 2.5 3 0 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2263) MFS_1 PF07690.11 EIW80769.1 - 7.9e-19 67.5 31.4 6.5e-16 57.9 18.9 3.2 1 1 2 3 3 3 3 Major Facilitator Superfamily CopD PF05425.8 EIW80769.1 - 0.11 12.7 0.0 0.11 12.7 0.0 3.3 2 1 1 3 3 3 0 Copper resistance protein D MFS_1 PF07690.11 EIW80770.1 - 1e-39 136.2 21.7 1e-39 136.2 15.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Oxidored_q2 PF00420.19 EIW80770.1 - 0.024 14.2 1.4 2.8 7.5 0.0 3.4 3 1 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF1469 PF07332.6 EIW80770.1 - 1.9 8.2 0.0 1.9 8.2 0.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF1469) DUF4470 PF14737.1 EIW80771.1 - 9.9e-22 76.5 0.0 2e-21 75.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EIW80771.1 - 2.2e-12 46.6 16.6 1.6e-11 43.8 10.5 2.7 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.1 EIW80771.1 - 1.4 8.8 7.5 3.6 7.5 5.2 1.7 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 La PF05383.12 EIW80773.1 - 1.9e-13 49.9 0.0 3.8e-13 49.0 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EIW80773.1 - 2.1e-05 24.0 0.8 0.00019 20.9 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW80773.1 - 0.0054 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.27 EIW80774.1 - 3.6e-123 397.5 45.5 8.9e-12 44.4 0.0 14.3 14 0 0 14 14 14 14 WD domain, G-beta repeat eIF2A PF08662.6 EIW80774.1 - 8.8e-18 64.7 0.1 4.1e-05 23.3 0.0 7.0 4 2 2 7 7 7 3 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EIW80774.1 - 2.3e-07 30.2 3.4 9.8 5.1 0.0 7.8 4 3 3 8 8 8 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 EIW80774.1 - 1.2e-06 28.0 16.1 2.9 7.6 0.0 10.4 12 0 0 12 12 12 2 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 EIW80774.1 - 0.00035 19.4 0.1 0.1 11.3 0.0 3.5 2 2 1 3 3 3 1 Nup133 N terminal like Nup160 PF11715.3 EIW80774.1 - 0.0028 15.8 7.5 9.4 4.2 0.1 6.7 3 2 3 6 6 6 2 Nucleoporin Nup120/160 AMP-binding PF00501.23 EIW80775.1 - 5e-77 259.0 0.0 6.7e-77 258.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIW80775.1 - 2.2e-12 47.7 1.5 4.7e-12 46.6 1.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Gln-synt_C PF00120.19 EIW80776.1 - 2.1e-54 184.4 0.0 3e-54 183.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain DUF677 PF05055.7 EIW80777.1 - 0.081 11.5 0.1 0.1 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF3245 PF11595.3 EIW80777.1 - 3.2 8.0 7.5 1.8 8.8 3.3 1.9 1 1 0 2 2 2 0 Protein of unknown function (DUF3245) Transposase_21 PF02992.9 EIW80779.1 - 0.00024 20.2 1.1 0.00054 19.1 0.1 1.8 2 0 0 2 2 2 1 Transposase family tnp2 DUF4218 PF13960.1 EIW80779.1 - 0.0023 17.3 0.1 0.0068 15.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Peptidase_C14 PF00656.17 EIW80780.1 - 6.3e-65 219.3 0.0 1e-64 218.6 0.0 1.3 1 0 0 1 1 1 1 Caspase domain Peptidase_C14 PF00656.17 EIW80781.1 - 5.1e-69 232.7 0.0 6e-69 232.4 0.0 1.0 1 0 0 1 1 1 1 Caspase domain AnfO_nitrog PF09582.5 EIW80785.1 - 0.16 11.1 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Iron only nitrogenase protein AnfO (AnfO_nitrog) Methyltransf_2 PF00891.13 EIW80787.1 - 5.1e-28 97.8 0.0 1e-27 96.9 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EIW80787.1 - 0.00041 20.8 0.0 0.002 18.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW80787.1 - 0.0019 18.6 0.0 0.0073 16.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Dimerisation PF08100.6 EIW80787.1 - 0.012 15.3 0.1 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain MTS PF05175.9 EIW80787.1 - 0.086 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain WD40 PF00400.27 EIW80788.1 - 3.1e-97 315.3 36.6 1e-10 41.0 0.0 13.1 13 0 0 13 13 13 12 WD domain, G-beta repeat Nbas_N PF15492.1 EIW80788.1 - 4.4e-08 32.5 0.7 0.24 10.4 0.0 5.4 5 2 2 7 7 7 3 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.6 EIW80788.1 - 2.4e-07 30.6 0.0 0.015 14.9 0.0 3.5 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIW80788.1 - 1.3e-06 26.8 10.6 0.73 7.9 0.0 6.4 3 2 1 6 6 6 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EIW80788.1 - 1.6e-06 27.7 3.3 0.066 12.6 0.4 5.1 2 1 1 3 3 3 2 PQQ-like domain Nucleoporin_N PF08801.6 EIW80788.1 - 6e-06 25.2 0.5 0.89 8.2 0.0 5.7 2 2 3 5 5 5 1 Nup133 N terminal like PD40 PF07676.7 EIW80788.1 - 6.9e-06 25.6 5.0 0.72 9.5 0.0 6.4 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat PQQ PF01011.16 EIW80788.1 - 0.0061 16.0 0.2 5.6 6.6 0.0 3.9 3 0 0 3 3 3 1 PQQ enzyme repeat Hira PF07569.6 EIW80788.1 - 0.017 14.3 0.0 4.8 6.3 0.0 3.4 4 1 0 4 4 4 0 TUP1-like enhancer of split YhzD PF14120.1 EIW80788.1 - 0.15 11.9 0.3 0.82 9.6 0.2 2.3 1 0 0 1 1 1 0 YhzD-like protein Methyltransf_2 PF00891.13 EIW80789.1 - 1.4e-29 103.0 0.0 2.8e-29 102.0 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EIW80789.1 - 6.2e-06 26.7 0.0 8.2e-05 23.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 EIW80789.1 - 0.00039 19.9 0.0 0.029 13.8 0.0 2.4 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_12 PF08242.7 EIW80789.1 - 0.00061 20.2 0.0 0.028 14.9 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain MTS PF05175.9 EIW80789.1 - 0.00076 18.9 0.0 0.0016 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.7 EIW80789.1 - 0.0031 17.1 0.0 0.0057 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_23 PF13489.1 EIW80789.1 - 0.0043 16.7 0.0 0.01 15.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 EIW80789.1 - 0.022 13.9 0.0 0.069 12.2 0.0 1.8 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Methyltransf_31 PF13847.1 EIW80789.1 - 0.023 14.2 0.0 0.12 11.9 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.12 EIW80789.1 - 0.084 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase HEAT_2 PF13646.1 EIW80790.1 - 0.061 13.6 0.4 8.8 6.6 0.0 2.6 2 0 0 2 2 2 0 HEAT repeats DUF11 PF01345.13 EIW80791.1 - 0.46 10.5 4.3 0.16 12.0 0.6 2.0 2 1 0 2 2 2 0 Domain of unknown function DUF11 ADH_zinc_N PF00107.21 EIW80792.1 - 5.7e-15 55.0 0.9 1.5e-14 53.6 0.2 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW80792.1 - 1.4e-10 40.9 0.0 2.4e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIW80792.1 - 1.9e-05 25.5 2.5 2.5e-05 25.1 0.3 2.1 2 1 0 2 2 2 1 Zinc-binding dehydrogenase TRAP_alpha PF03896.11 EIW80793.1 - 3.5 6.5 5.7 7.6 5.4 3.9 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4218 PF13960.1 EIW80794.1 - 0.0025 17.2 0.1 0.0045 16.4 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) ADH_zinc_N PF00107.21 EIW80795.1 - 1.9e-16 59.7 0.2 3.9e-16 58.7 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW80795.1 - 3.3e-10 39.6 0.1 5.6e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIW80795.1 - 2.6e-06 28.3 1.0 5.2e-06 27.3 0.7 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 EIW80795.1 - 0.14 11.9 0.1 0.14 11.9 0.1 2.5 3 0 0 3 3 3 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase AAA_16 PF13191.1 EIW80796.1 - 3.1e-08 33.8 0.0 3.3e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EIW80796.1 - 1.1e-07 31.7 0.0 1.4e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.17 EIW80796.1 - 1.9e-05 24.8 0.0 2.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 EIW80796.1 - 2.2e-05 24.7 0.0 2.9e-05 24.3 0.0 1.3 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EIW80796.1 - 2.5e-05 23.9 0.0 3.7e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.1 EIW80796.1 - 3.3e-05 24.0 0.0 3.7e-05 23.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW80796.1 - 0.00013 22.7 0.0 0.00018 22.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIW80796.1 - 0.00044 20.5 0.0 0.00052 20.3 0.0 1.4 1 1 0 1 1 1 1 ABC transporter PRK PF00485.13 EIW80796.1 - 0.0006 19.4 0.0 0.00071 19.1 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA PF00004.24 EIW80796.1 - 0.00085 19.5 0.0 0.00096 19.3 0.0 1.3 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EIW80796.1 - 0.0016 18.2 0.0 0.0022 17.7 0.0 1.3 1 1 0 1 1 1 1 NTPase Cytidylate_kin2 PF13189.1 EIW80796.1 - 0.0026 17.7 0.1 0.0048 16.8 0.0 1.4 1 0 0 1 1 1 1 Cytidylate kinase-like family UPF0079 PF02367.12 EIW80796.1 - 0.0059 16.2 0.0 0.007 15.9 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 EIW80796.1 - 0.0087 15.7 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EIW80796.1 - 0.0095 15.1 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 EIW80796.1 - 0.015 15.1 0.0 0.019 14.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain CbiA PF01656.18 EIW80796.1 - 0.018 14.4 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NB-ARC PF00931.17 EIW80796.1 - 0.022 13.6 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.1 EIW80796.1 - 0.023 14.5 0.0 0.033 14.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_31 PF13614.1 EIW80796.1 - 0.024 14.5 0.0 0.036 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain SKI PF01202.17 EIW80796.1 - 0.032 14.1 0.1 0.059 13.2 0.0 1.5 2 0 0 2 2 1 0 Shikimate kinase DUF2075 PF09848.4 EIW80796.1 - 0.036 13.0 0.0 0.036 13.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.9 EIW80796.1 - 0.036 13.7 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Rad17 PF03215.10 EIW80796.1 - 0.041 12.5 0.0 0.046 12.3 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_29 PF13555.1 EIW80796.1 - 0.042 13.3 0.1 0.079 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EIW80796.1 - 0.059 13.0 0.0 0.059 13.0 0.0 1.1 1 0 0 1 1 1 0 Archaeal ATPase Zeta_toxin PF06414.7 EIW80796.1 - 0.066 12.2 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RuvB_N PF05496.7 EIW80796.1 - 0.082 11.9 0.0 0.36 9.8 0.0 1.8 1 1 1 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 EIW80796.1 - 0.096 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain ArgK PF03308.11 EIW80796.1 - 0.1 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Uds1 PF15456.1 EIW80797.1 - 0.34 10.8 3.6 2.8 7.9 0.5 2.3 2 1 0 2 2 2 0 Up-regulated During Septation Cauli_VI PF01693.11 EIW80798.1 - 0.0015 18.4 0.1 0.0031 17.4 0.1 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin End3 PF12761.2 EIW80799.1 - 0.17 11.5 2.8 1.1 8.8 0.0 2.7 2 1 0 3 3 3 0 Actin cytoskeleton-regulatory complex protein END3 HMG_box PF00505.14 EIW80799.1 - 0.65 10.3 8.1 0.035 14.3 1.2 2.2 2 0 0 2 2 2 0 HMG (high mobility group) box HMG_box_2 PF09011.5 EIW80799.1 - 2.2 8.6 6.6 0.16 12.3 0.4 2.1 2 0 0 2 2 2 0 HMG-box domain E1-E2_ATPase PF00122.15 EIW80800.1 - 1.4e-17 63.4 0.0 2.5e-17 62.6 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EIW80800.1 - 2.2e-17 63.8 0.0 7.1e-17 62.1 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIW80800.1 - 2.3e-13 49.8 0.0 6e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EIW80800.1 - 3.8e-12 47.0 3.3 6.3e-11 43.0 1.2 3.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIW80800.1 - 0.0058 16.2 0.1 0.014 14.9 0.0 1.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIW80800.1 - 0.13 12.4 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Asp PF00026.18 EIW80801.1 - 6.9e-41 140.5 5.4 8.2e-41 140.2 3.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EIW80801.1 - 1.7e-05 24.4 0.0 3.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EIW80801.1 - 0.00011 22.2 0.1 0.00088 19.2 0.0 2.4 2 2 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIW80801.1 - 0.00022 21.6 2.8 0.0024 18.3 0.8 2.8 2 1 0 2 2 2 1 Aspartyl protease Pyridoxal_deC PF00282.14 EIW80802.1 - 7.3e-111 370.1 0.0 8.8e-111 369.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain NESP55 PF06390.7 EIW80802.1 - 0.00085 18.7 0.4 0.0014 18.0 0.3 1.3 1 0 0 1 1 1 1 Neuroendocrine-specific golgi protein P55 (NESP55) DUF3602 PF12223.3 EIW80803.1 - 3.8e-11 43.2 18.0 0.00025 21.3 1.0 3.8 2 1 2 4 4 4 3 Protein of unknown function (DUF3602) DAO PF01266.19 EIW80804.1 - 1.4e-35 122.8 1.1 2.4e-35 122.0 0.7 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIW80804.1 - 0.00081 19.3 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIW80804.1 - 0.00087 19.0 0.1 0.0023 17.7 0.1 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EIW80804.1 - 0.00088 19.2 0.1 0.0023 17.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF498 PF04430.9 EIW80804.1 - 0.0032 17.0 0.0 0.012 15.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF498/DUF598) Pyr_redox_3 PF13738.1 EIW80804.1 - 0.0087 16.1 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW80804.1 - 0.025 13.4 0.7 0.038 12.8 0.5 1.4 1 1 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EIW80804.1 - 0.028 13.4 0.1 0.062 12.3 0.0 1.5 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 EIW80804.1 - 0.049 12.5 0.1 0.09 11.6 0.1 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein K_oxygenase PF13434.1 EIW80804.1 - 0.12 11.3 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) F-box-like PF12937.2 EIW80805.1 - 3e-06 26.8 4.9 3.2e-06 26.7 0.8 2.7 2 1 0 2 2 2 1 F-box-like Pkinase PF00069.20 EIW80806.1 - 1.7e-30 106.0 0.0 2.1e-30 105.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW80806.1 - 9.3e-26 90.4 0.0 1.1e-25 90.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW80806.1 - 0.00043 19.3 0.0 0.00054 19.0 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW80806.1 - 0.00089 19.0 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EIW80806.1 - 0.045 12.5 0.0 0.058 12.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase C2 PF00168.25 EIW80807.1 - 1.6e-11 43.8 0.0 2.8e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain Pkinase PF00069.20 EIW80808.1 - 5.4e-27 94.5 0.0 6.4e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW80808.1 - 1.3e-24 86.7 0.0 1.5e-24 86.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW80808.1 - 0.00039 20.2 0.0 0.00064 19.5 0.0 1.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIW80808.1 - 0.0018 17.6 0.0 0.0042 16.4 0.0 1.7 2 1 1 3 3 3 1 RIO1 family DUF218 PF02698.12 EIW80810.1 - 0.00046 19.7 0.3 0.056 12.9 0.0 2.3 2 0 0 2 2 2 2 DUF218 domain DUF3328 PF11807.3 EIW80810.1 - 0.068 12.8 0.3 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) GIT_SHD PF08518.6 EIW80811.1 - 1.3e-25 88.4 4.0 1.6e-13 49.7 1.0 2.9 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT Lebercilin PF15619.1 EIW80811.1 - 0.0072 15.7 12.2 0.0072 15.7 8.4 2.6 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease FH2 PF02181.18 EIW80811.1 - 0.013 14.3 2.3 0.93 8.3 0.3 2.2 2 0 0 2 2 2 0 Formin Homology 2 Domain Seryl_tRNA_N PF02403.17 EIW80811.1 - 0.14 12.1 11.5 2.5 8.1 1.6 3.3 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain V_ATPase_I PF01496.14 EIW80811.1 - 2.1 6.0 5.9 0.55 8.0 1.6 1.7 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF972 PF06156.8 EIW80811.1 - 7.1 7.0 11.8 27 5.1 3.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Fmp27_WPPW PF10359.4 EIW80811.1 - 9.3 4.5 10.1 1.5 7.1 3.9 1.7 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Glyco_hydro_cc PF11790.3 EIW80812.1 - 4.5e-37 127.7 0.1 5.3e-37 127.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Pkinase PF00069.20 EIW80813.1 - 3.3e-40 137.8 0.0 4e-40 137.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW80813.1 - 2.8e-36 124.9 0.0 3.2e-36 124.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW80813.1 - 1.2e-05 25.1 0.0 0.00017 21.3 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW80813.1 - 0.0046 15.9 0.0 0.006 15.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like F-box-like PF12937.2 EIW80815.1 - 5.4e-07 29.2 0.2 1.9e-06 27.4 0.1 2.0 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EIW80815.1 - 0.93 9.2 7.5 24 4.6 3.2 3.4 2 1 0 2 2 2 0 F-box domain Asp PF00026.18 EIW80816.1 - 8.6e-51 173.0 22.5 1.5e-50 172.2 15.6 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW80816.1 - 1.1e-06 28.7 6.0 1.1e-06 28.7 4.2 3.6 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIW80816.1 - 0.003 17.9 8.6 0.027 14.9 1.6 2.9 2 1 0 2 2 2 2 Aspartyl protease FAD_binding_3 PF01494.14 EIW80818.1 - 6.5e-74 249.1 0.0 9e-74 248.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EIW80818.1 - 1.4e-07 31.7 0.0 0.0027 18.0 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW80818.1 - 1.7e-07 30.4 1.4 0.00022 20.1 0.0 2.5 3 0 0 3 3 3 2 FAD binding domain HI0933_like PF03486.9 EIW80818.1 - 3.1e-06 25.9 0.1 0.0016 17.0 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 EIW80818.1 - 2.5e-05 24.2 0.1 8e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIW80818.1 - 3.8e-05 22.9 1.6 0.0081 15.2 0.1 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Thi4 PF01946.12 EIW80818.1 - 6.4e-05 22.1 0.0 0.00021 20.4 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EIW80818.1 - 0.00017 21.5 0.0 0.00056 19.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIW80818.1 - 0.0006 18.8 0.7 0.0035 16.2 0.0 2.4 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIW80818.1 - 0.00091 19.3 0.1 0.0023 18.0 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIW80818.1 - 0.0015 17.4 0.0 0.0022 16.9 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 EIW80818.1 - 0.031 13.9 0.0 0.065 12.8 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 EIW80818.1 - 0.037 13.8 0.1 0.067 13.0 0.1 1.4 1 0 0 1 1 1 0 ThiF family AlaDh_PNT_C PF01262.16 EIW80818.1 - 0.086 12.4 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 EIW80818.1 - 0.094 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Trp_halogenase PF04820.9 EIW80818.1 - 0.096 11.2 0.1 0.21 10.1 0.0 1.5 1 1 1 2 2 2 0 Tryptophan halogenase Asp PF00026.18 EIW80819.1 - 1.4e-51 175.6 16.6 3.4e-51 174.3 11.5 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW80819.1 - 2.2e-07 30.9 5.6 1.7e-06 28.1 1.6 3.3 1 1 2 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIW80819.1 - 3.3e-05 24.2 4.7 0.015 15.8 0.5 2.7 2 1 0 2 2 2 2 Aspartyl protease Asp PF00026.18 EIW80820.1 - 5.2e-51 173.7 16.8 1.1e-50 172.6 11.6 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW80820.1 - 2.3e-06 27.6 6.4 9.6e-06 25.6 2.2 3.0 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIW80820.1 - 0.00014 22.2 5.6 0.048 14.1 0.6 2.9 2 1 0 2 2 2 2 Aspartyl protease Trp_halogenase PF04820.9 EIW80822.1 - 4.8e-28 97.9 0.5 5.1e-15 55.0 0.0 2.3 1 1 1 2 2 2 2 Tryptophan halogenase FAD_binding_3 PF01494.14 EIW80822.1 - 9.6e-10 38.0 0.1 2.1e-08 33.6 0.0 2.6 2 1 0 2 2 2 1 FAD binding domain DAO PF01266.19 EIW80822.1 - 4.9e-06 25.6 0.0 4.3e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIW80822.1 - 6.7e-06 26.1 0.0 1.4e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW80822.1 - 8e-06 25.7 0.1 3e-05 23.9 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIW80822.1 - 1.6e-05 23.9 0.1 3.3e-05 22.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EIW80822.1 - 2.8e-05 22.7 0.1 5.2e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 EIW80822.1 - 9.2e-05 21.6 0.3 0.00024 20.2 0.2 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EIW80822.1 - 0.00024 20.1 0.0 0.00035 19.5 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 EIW80822.1 - 0.003 16.7 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EIW80822.1 - 0.017 15.5 0.0 0.043 14.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW80822.1 - 0.031 14.3 0.0 0.066 13.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIW80822.1 - 0.033 13.1 0.1 0.069 12.0 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein ThiF PF00899.16 EIW80822.1 - 0.063 13.0 0.1 0.23 11.2 0.3 1.8 2 0 0 2 2 2 0 ThiF family NAD_binding_7 PF13241.1 EIW80822.1 - 0.13 12.5 0.0 0.3 11.3 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding LCAT PF02450.10 EIW80823.1 - 1.2e-66 225.3 0.0 1.6e-65 221.6 0.0 2.0 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 EIW80823.1 - 0.0072 15.6 0.0 0.016 14.5 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 2) DUF900 PF05990.7 EIW80823.1 - 0.092 12.0 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Isochorismatase PF00857.15 EIW80824.1 - 2.5e-25 89.3 0.0 4.8e-23 81.9 0.0 2.9 1 1 0 1 1 1 1 Isochorismatase family AAA_16 PF13191.1 EIW80826.1 - 5.5e-07 29.7 0.1 6e-07 29.6 0.1 1.1 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EIW80826.1 - 5.5e-06 26.1 0.0 8.1e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EIW80826.1 - 2.3e-05 24.5 0.0 4.1e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EIW80826.1 - 3.9e-05 23.7 0.0 5.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 RNA helicase APS_kinase PF01583.15 EIW80826.1 - 4.4e-05 23.2 0.0 6.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase DUF258 PF03193.11 EIW80826.1 - 0.0002 20.5 0.0 0.0002 20.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EIW80826.1 - 0.00032 20.9 0.0 0.0005 20.3 0.0 1.3 1 1 0 1 1 1 1 ABC transporter Arch_ATPase PF01637.13 EIW80826.1 - 0.00038 20.2 0.0 0.00039 20.1 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase AAA_18 PF13238.1 EIW80826.1 - 0.00047 20.4 0.0 0.00058 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW80826.1 - 0.00049 19.9 0.0 0.00077 19.3 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW80826.1 - 0.0011 19.8 0.1 0.0019 19.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EIW80826.1 - 0.0011 18.4 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EIW80826.1 - 0.0021 17.2 0.0 0.0029 16.7 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin PRK PF00485.13 EIW80826.1 - 0.0027 17.3 0.0 0.0037 16.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.17 EIW80826.1 - 0.004 16.0 0.0 0.0043 15.9 0.0 1.1 1 0 0 1 1 1 1 NB-ARC domain DUF2075 PF09848.4 EIW80826.1 - 0.0082 15.1 0.0 0.0086 15.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 EIW80826.1 - 0.0082 15.8 0.0 0.013 15.1 0.0 1.4 1 1 0 1 1 1 1 NTPase MobB PF03205.9 EIW80826.1 - 0.01 15.5 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.5 EIW80826.1 - 0.013 14.7 0.0 0.014 14.6 0.0 1.3 1 1 0 1 1 1 0 Chromatin associated protein KTI12 UPF0079 PF02367.12 EIW80826.1 - 0.013 15.1 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 EIW80826.1 - 0.014 14.3 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EIW80826.1 - 0.019 14.4 0.0 0.024 14.1 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sigma54_activ_2 PF14532.1 EIW80826.1 - 0.02 14.9 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activat PF00158.21 EIW80826.1 - 0.022 14.2 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.24 EIW80826.1 - 0.028 14.6 0.0 0.053 13.7 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EIW80826.1 - 0.034 14.0 0.0 0.042 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EIW80826.1 - 0.035 12.7 0.0 0.041 12.5 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein IstB_IS21 PF01695.12 EIW80826.1 - 0.038 13.4 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 EIW80826.1 - 0.043 12.5 0.0 0.046 12.4 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus AAA_5 PF07728.9 EIW80826.1 - 0.047 13.4 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EIW80826.1 - 0.049 12.6 0.0 0.21 10.6 0.0 1.8 1 1 1 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EIW80826.1 - 0.057 12.3 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_10 PF12846.2 EIW80826.1 - 0.069 12.5 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain DEAD PF00270.24 EIW80826.1 - 0.07 12.6 0.0 0.31 10.5 0.0 1.8 1 1 1 2 2 2 0 DEAD/DEAH box helicase PIF1 PF05970.9 EIW80826.1 - 0.07 12.0 0.0 0.083 11.8 0.0 1.1 1 0 0 1 1 1 0 PIF1-like helicase FAM180 PF15173.1 EIW80826.1 - 0.076 12.7 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 FAM180 family AAA_19 PF13245.1 EIW80826.1 - 0.088 12.5 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain CPT PF07931.7 EIW80826.1 - 0.089 12.4 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein PhoH PF02562.11 EIW80826.1 - 0.13 11.5 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein CbiA PF01656.18 EIW80826.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain IGPS PF00218.16 EIW80827.1 - 2e-88 295.7 0.0 3.6e-88 294.8 0.0 1.4 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase GATase PF00117.23 EIW80827.1 - 4.3e-48 163.3 0.0 8e-48 162.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I PRAI PF00697.17 EIW80827.1 - 1.2e-45 155.4 0.1 1e-39 136.1 0.0 3.1 2 1 0 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase Peptidase_C26 PF07722.8 EIW80827.1 - 1.3e-06 28.0 0.1 5.3e-06 26.0 0.0 2.1 3 0 0 3 3 3 1 Peptidase C26 QRPTase_C PF01729.14 EIW80827.1 - 0.16 11.4 0.0 0.69 9.4 0.0 2.0 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain F-box-like PF12937.2 EIW80829.1 - 0.045 13.4 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 F-box-like Actin PF00022.14 EIW80830.1 - 8.9e-90 300.9 0.0 1.8e-89 299.9 0.0 1.4 1 1 0 1 1 1 1 Actin TPR_11 PF13414.1 EIW80831.1 - 2.3e-15 55.9 3.1 2.1e-07 30.4 0.0 3.4 2 1 2 4 4 4 3 TPR repeat PB1 PF00564.19 EIW80831.1 - 2.3e-10 39.9 0.0 4e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 PB1 domain TPR_2 PF07719.12 EIW80831.1 - 1e-09 37.5 6.4 0.011 15.6 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EIW80831.1 - 6.3e-07 28.7 3.6 0.0085 15.6 0.0 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIW80831.1 - 0.00012 21.8 0.6 0.0021 17.9 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIW80831.1 - 0.00084 18.9 2.9 0.072 12.9 0.0 4.0 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIW80831.1 - 0.0041 16.8 2.1 1.2 9.1 0.0 4.2 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIW80831.1 - 0.027 14.9 3.3 51 4.6 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIW80831.1 - 0.061 14.0 7.2 0.53 11.0 1.3 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EIW80831.1 - 0.066 13.4 0.3 2 8.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat CMAS PF02353.15 EIW80833.1 - 1.5e-62 211.1 0.0 1.9e-62 210.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EIW80833.1 - 2.9e-12 46.6 0.1 1.5e-11 44.3 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW80833.1 - 1.8e-08 34.7 0.0 2e-07 31.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW80833.1 - 7.6e-06 26.4 0.0 3.1e-05 24.5 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW80833.1 - 0.00041 20.7 0.0 0.00091 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW80833.1 - 0.00042 20.3 0.2 0.0024 17.8 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.8 EIW80833.1 - 0.0021 17.3 0.0 0.004 16.4 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.9 EIW80833.1 - 0.0034 16.7 0.0 0.0068 15.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EIW80833.1 - 0.017 15.4 0.0 0.07 13.5 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain PCMT PF01135.14 EIW80833.1 - 0.032 13.7 0.0 0.075 12.5 0.0 1.6 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EIW80833.1 - 0.037 13.6 0.0 0.081 12.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Fic PF02661.13 EIW80835.1 - 5.9e-11 42.9 0.0 9.2e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Fic/DOC family Pkinase PF00069.20 EIW80836.1 - 8.5e-68 228.3 0.0 1.1e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW80836.1 - 7.7e-29 100.5 0.0 1.1e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW80836.1 - 0.02 14.6 0.1 0.069 12.8 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW80836.1 - 0.06 12.2 0.0 0.15 10.9 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Asp PF00026.18 EIW80837.1 - 9.5e-51 172.9 10.1 2.4e-50 171.5 7.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EIW80837.1 - 3.1e-07 30.7 4.5 0.0013 19.1 0.7 2.5 2 0 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EIW80837.1 - 6.4e-06 26.2 5.1 9.3e-05 22.4 2.3 2.7 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 EIW80837.1 - 0.02 14.6 0.4 6.4 6.6 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Abhydro_lipase PF04083.11 EIW80839.1 - 1.1e-23 82.3 0.2 1.1e-22 79.1 0.0 2.5 3 0 0 3 3 3 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EIW80839.1 - 5.9e-19 68.5 0.2 8.6e-19 67.9 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIW80839.1 - 1.4e-10 41.4 0.8 2.5e-10 40.6 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW80839.1 - 8.5e-07 28.8 0.0 3.5e-06 26.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EIW80839.1 - 0.00061 19.3 0.0 0.17 11.3 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) SNF2_N PF00176.18 EIW80849.1 - 1.8e-53 181.3 0.1 2.1e-53 181.0 0.1 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EIW80849.1 - 0.041 13.7 0.0 0.088 12.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF3453 PF11935.3 EIW80849.1 - 0.042 13.2 0.4 0.79 9.0 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3453) Phage_GP20 PF06810.6 EIW80849.1 - 0.11 11.9 0.2 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 SNF2_N PF00176.18 EIW80853.1 - 5.6e-24 84.4 0.1 6e-24 84.3 0.0 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain LEF-8 PF04941.7 EIW80853.1 - 0.0055 14.4 0.1 0.0066 14.1 0.1 1.0 1 0 0 1 1 1 1 Late expression factor 8 (LEF-8) ResIII PF04851.10 EIW80853.1 - 0.011 15.5 0.0 0.012 15.5 0.0 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PIF1 PF05970.9 EIW80855.1 - 1.3e-31 109.8 0.2 1.5e-31 109.7 0.2 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EIW80855.1 - 2.5e-05 23.9 0.0 2.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW80855.1 - 5.7e-05 22.7 0.0 8.9e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EIW80855.1 - 0.00013 22.0 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 EIW80855.1 - 0.0016 17.8 0.7 0.0021 17.4 0.4 1.5 1 1 0 1 1 1 1 IstB-like ATP binding protein ResIII PF04851.10 EIW80855.1 - 0.0034 17.2 0.0 0.004 17.0 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit PhoH PF02562.11 EIW80855.1 - 0.0034 16.6 0.0 0.0034 16.6 0.0 1.2 1 0 0 1 1 1 1 PhoH-like protein AAA_25 PF13481.1 EIW80855.1 - 0.004 16.5 0.0 0.0042 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF2791 PF10923.3 EIW80855.1 - 0.017 13.7 0.0 0.017 13.7 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) CbiA PF01656.18 EIW80855.1 - 0.02 14.3 0.1 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RNA_helicase PF00910.17 EIW80855.1 - 0.022 14.9 0.1 0.1 12.7 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 EIW80855.1 - 0.037 14.2 0.1 0.048 13.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EIW80855.1 - 0.042 12.9 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 KaiC Torsin PF06309.6 EIW80855.1 - 0.044 13.6 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_5 PF07728.9 EIW80855.1 - 0.054 13.2 0.1 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 EIW80855.1 - 0.12 11.3 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EIW80855.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family NNMT_PNMT_TEMT PF01234.12 EIW80855.1 - 0.12 11.2 0.2 0.17 10.8 0.1 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family AAA_22 PF13401.1 EIW80855.1 - 0.14 12.3 0.3 0.2 11.7 0.2 1.6 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EIW80855.1 - 0.14 11.1 0.1 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Pkinase PF00069.20 EIW80859.1 - 1.9e-07 30.4 0.0 0.0003 20.0 0.0 2.3 1 1 1 2 2 2 2 Protein kinase domain SpoVS PF04232.7 EIW80860.1 - 0.088 12.3 0.3 13 5.4 0.1 2.4 2 0 0 2 2 2 0 Stage V sporulation protein S (SpoVS) API5 PF05918.6 EIW80869.1 - 5.2 5.4 7.0 9.3 4.6 4.9 1.3 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Transposase_21 PF02992.9 EIW80870.1 - 1.8e-09 37.0 0.1 2.2e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 Ig_2 PF13895.1 EIW80874.1 - 0.085 12.9 0.1 0.17 12.0 0.1 1.7 1 1 0 1 1 1 0 Immunoglobulin domain Glyco_hydro_28 PF00295.12 EIW80875.1 - 7.8e-58 195.9 10.0 9.8e-58 195.6 7.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 TPR_MLP1_2 PF07926.7 EIW80876.1 - 2.6e-21 75.7 15.7 2.6e-21 75.7 10.9 15.3 6 4 9 15 15 15 5 TPR/MLP1/MLP2-like protein ATG16 PF08614.6 EIW80876.1 - 0.0001 22.1 9.3 0.0001 22.1 6.5 13.8 3 2 9 15 15 15 5 Autophagy protein 16 (ATG16) Myosin_tail_1 PF01576.14 EIW80876.1 - 0.00075 17.3 18.8 0.00075 17.3 13.0 8.9 4 3 4 8 8 8 2 Myosin tail DUF726 PF05277.7 EIW80877.1 - 0.074 11.9 0.0 0.095 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Pkinase PF00069.20 EIW80878.1 - 0.0002 20.5 0.0 0.00023 20.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PsbT PF01405.12 EIW80878.1 - 0.2 11.2 1.0 0.55 9.8 0.7 1.8 1 0 0 1 1 1 0 Photosystem II reaction centre T protein Pkinase PF00069.20 EIW80879.1 - 3.7e-44 150.8 0.0 4.3e-44 150.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW80879.1 - 5.1e-23 81.4 0.0 2.8e-22 79.0 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW80879.1 - 1.5e-09 37.2 0.0 2.1e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW80879.1 - 0.00012 21.9 0.0 0.00022 21.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIW80879.1 - 0.0095 15.2 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.6 EIW80879.1 - 0.14 10.9 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase WD40 PF00400.27 EIW80880.1 - 4.6e-49 162.6 26.8 1.3e-12 47.0 1.4 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat PD40 PF07676.7 EIW80880.1 - 6.6e-06 25.6 1.1 1.1 8.9 0.1 4.7 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 EIW80880.1 - 1.3e-05 24.7 0.2 0.017 14.6 0.0 2.8 1 1 1 3 3 3 2 PQQ-like domain Nup160 PF11715.3 EIW80880.1 - 0.0025 16.0 0.0 0.22 9.6 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EIW80880.1 - 0.051 13.8 2.9 7.7 6.9 0.1 3.9 4 1 0 4 4 4 0 PQQ-like domain Homeobox PF00046.24 EIW80881.1 - 5.3e-06 25.9 0.9 0.00025 20.5 0.6 2.4 1 1 0 1 1 1 1 Homeobox domain RHH_1 PF01402.16 EIW80881.1 - 0.0013 18.5 0.1 0.0028 17.4 0.1 1.6 1 0 0 1 1 1 1 Ribbon-helix-helix protein, copG family Homeobox_KN PF05920.6 EIW80881.1 - 0.0092 15.6 0.1 0.024 14.3 0.1 1.6 1 0 0 1 1 1 1 Homeobox KN domain HTH_28 PF13518.1 EIW80881.1 - 0.013 15.4 0.4 0.036 14.0 0.3 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.1 EIW80881.1 - 0.016 14.8 0.3 0.032 13.8 0.2 1.4 1 0 0 1 1 1 0 Homeodomain-like domain MerR_1 PF13411.1 EIW80881.1 - 0.26 11.0 0.3 0.55 10.0 0.2 1.5 1 0 0 1 1 1 0 MerR HTH family regulatory protein Porin_3 PF01459.17 EIW80882.1 - 1.8e-62 211.1 2.0 2e-62 210.9 1.4 1.0 1 0 0 1 1 1 1 Eukaryotic porin Cofilin_ADF PF00241.15 EIW80883.1 - 6.9e-39 132.6 0.1 7.6e-39 132.4 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein CH PF00307.26 EIW80884.1 - 5.7e-45 151.8 0.0 1.4e-24 86.1 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EIW80884.1 - 5.2e-16 58.3 1.2 1.8e-15 56.6 0.0 2.5 3 0 0 3 3 3 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EIW80884.1 - 2.5e-15 55.8 0.1 5.8e-11 41.8 0.0 2.7 2 1 0 2 2 2 2 CAMSAP CH domain PBP_GOBP PF01395.17 EIW80884.1 - 0.0067 16.0 0.2 0.02 14.5 0.0 1.8 2 0 0 2 2 2 1 PBP/GOBP family EF-hand_6 PF13405.1 EIW80884.1 - 0.013 15.3 0.0 0.24 11.3 0.0 2.8 2 0 0 2 2 2 0 EF-hand domain COG2 PF06148.6 EIW80884.1 - 0.016 15.0 0.4 0.046 13.5 0.3 1.7 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 SSrecog PF03531.9 EIW80885.1 - 1.6e-75 253.2 0.0 2.7e-75 252.5 0.0 1.4 1 0 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EIW80885.1 - 3.2e-23 81.5 0.0 1.2e-21 76.4 0.0 2.6 2 0 0 2 2 2 1 Histone chaperone Rttp106-like PQQ_3 PF13570.1 EIW80886.1 - 0.0001 22.4 0.5 0.84 9.9 0.0 3.8 2 1 1 3 3 3 2 PQQ-like domain Nup160 PF11715.3 EIW80886.1 - 0.00028 19.1 0.0 0.00039 18.6 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin Nup120/160 WD40 PF00400.27 EIW80886.1 - 0.022 14.6 1.7 0.57 10.1 0.0 3.6 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF1830 PF08865.6 EIW80886.1 - 0.086 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1830) Rhodanese PF00581.15 EIW80887.1 - 2.8e-12 46.9 0.0 3.5e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain F-box-like PF12937.2 EIW80888.1 - 0.0049 16.5 8.2 0.011 15.4 4.4 2.7 2 1 0 2 2 2 1 F-box-like MIP PF00230.15 EIW80890.1 - 2.1e-51 174.5 11.2 2.5e-51 174.3 7.8 1.1 1 0 0 1 1 1 1 Major intrinsic protein Pkinase PF00069.20 EIW80891.1 - 9.9e-05 21.6 0.0 0.00012 21.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PsbT PF01405.12 EIW80891.1 - 0.11 12.1 0.4 0.28 10.7 0.3 1.7 1 0 0 1 1 1 0 Photosystem II reaction centre T protein DUF726 PF05277.7 EIW80892.1 - 0.11 11.3 0.3 0.14 11.0 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF726) NTR2 PF15458.1 EIW80893.1 - 4e-61 206.4 10.5 4e-61 206.4 7.3 2.3 2 0 0 2 2 2 1 Nineteen complex-related protein 2 GCFC PF07842.7 EIW80893.1 - 0.0046 16.3 0.0 0.008 15.5 0.0 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein Rad60-SLD PF11976.3 EIW80894.1 - 1.5e-11 43.7 0.1 3.8e-09 36.0 0.3 3.2 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like RA PF00788.18 EIW80894.1 - 0.04 14.3 0.0 0.47 10.9 0.0 2.3 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain mRNA_triPase PF02940.10 EIW80895.1 - 1.5e-49 168.7 0.0 1.7e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain Zip PF02535.17 EIW80896.1 - 4.9e-23 81.6 10.8 8e-23 80.9 7.5 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter PhyH PF05721.8 EIW80897.1 - 6.2e-05 23.1 0.1 0.004 17.2 0.0 2.4 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Mit_KHE1 PF10173.4 EIW80899.1 - 8e-50 169.2 0.0 1.2e-49 168.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related GFO_IDH_MocA PF01408.17 EIW80900.1 - 5.1e-25 88.3 0.0 7.6e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EIW80900.1 - 8.8e-06 25.5 0.0 3.1e-05 23.7 0.0 1.9 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 EIW80900.1 - 0.0016 18.6 0.0 0.0038 17.5 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 EIW80900.1 - 0.033 14.7 0.0 0.059 13.9 0.0 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase PHP_C PF13263.1 EIW80900.1 - 0.12 11.8 0.7 2.8 7.5 0.1 2.8 3 0 0 3 3 3 0 PHP-associated Pkinase PF00069.20 EIW80901.1 - 1.8e-06 27.2 0.0 2.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EIW80901.1 - 0.042 13.5 0.1 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Toxin_49 PF15529.1 EIW80901.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Putative toxin 49 SKN1 PF03935.10 EIW80903.1 - 2.1e-183 610.0 1.6 2.5e-183 609.8 1.1 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.16 EIW80903.1 - 0.00051 19.3 2.6 0.0028 16.9 0.1 3.0 3 1 0 3 3 3 1 Glycosyl hydrolases family 16 SMC_N PF02463.14 EIW80906.1 - 1.9e-27 95.9 0.5 3e-27 95.2 0.4 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EIW80906.1 - 6e-18 65.9 8.5 6e-18 65.9 5.9 5.5 2 2 0 3 3 3 1 AAA domain AAA_21 PF13304.1 EIW80906.1 - 2.3e-06 27.8 0.0 0.0011 19.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EIW80906.1 - 1.4e-05 24.3 1.6 1.4e-05 24.3 1.1 2.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_29 PF13555.1 EIW80906.1 - 0.00017 21.0 0.0 0.00047 19.6 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain Filament PF00038.16 EIW80906.1 - 0.00038 20.0 15.2 0.00038 20.0 10.5 3.9 2 2 1 3 3 3 1 Intermediate filament protein Reo_sigmaC PF04582.7 EIW80906.1 - 0.0017 17.6 6.3 0.12 11.4 0.2 3.3 3 0 0 3 3 3 2 Reovirus sigma C capsid protein SbcCD_C PF13558.1 EIW80906.1 - 0.0075 16.1 0.0 0.02 14.8 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit EIAV_GP90 PF00971.13 EIW80907.1 - 0.17 10.3 0.0 0.23 9.8 0.0 1.2 1 0 0 1 1 1 0 EIAV coat protein, gp90 Peptidase_C48 PF02902.14 EIW80908.1 - 3e-15 56.4 0.2 3.6e-15 56.1 0.2 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Mur_ligase_M PF08245.7 EIW80909.1 - 3.5e-08 33.7 0.1 9.6e-08 32.2 0.1 1.7 1 1 0 1 1 1 1 Mur ligase middle domain SKN1 PF03935.10 EIW80910.1 - 6e-194 644.8 4.2 7e-194 644.6 2.9 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) ThiF PF00899.16 EIW80911.1 - 7.6e-20 71.1 0.1 1.2e-19 70.4 0.1 1.3 1 0 0 1 1 1 1 ThiF family DUF2924 PF11149.3 EIW80911.1 - 0.05 13.6 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) Fungal_trans PF04082.13 EIW80912.1 - 3.5e-22 78.5 0.0 6.8e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW80912.1 - 4.5e-08 32.8 11.1 8.6e-08 31.9 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PPR_2 PF13041.1 EIW80913.1 - 2.1e-08 33.9 0.0 0.00016 21.5 0.0 4.2 3 1 1 4 4 4 2 PPR repeat family Ank_2 PF12796.2 EIW80913.1 - 0.002 18.4 0.1 0.43 10.9 0.0 3.8 5 0 0 5 5 5 1 Ankyrin repeats (3 copies) PPR PF01535.15 EIW80913.1 - 0.05 13.5 1.6 1e+02 3.1 0.0 5.4 6 0 0 6 6 6 0 PPR repeat PPR_3 PF13812.1 EIW80913.1 - 0.15 12.4 16.9 2.2 8.7 0.1 6.7 7 0 0 7 7 7 0 Pentatricopeptide repeat domain PPR_1 PF12854.2 EIW80913.1 - 0.23 10.9 0.6 1.7 8.2 0.0 2.8 2 0 0 2 2 2 0 PPR repeat Ank_3 PF13606.1 EIW80913.1 - 0.43 10.9 2.6 8.3 6.9 0.1 4.3 5 0 0 5 5 5 0 Ankyrin repeat GRASP55_65 PF04495.9 EIW80915.1 - 1.7e-61 206.1 0.0 2e-43 147.7 0.0 2.1 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EIW80915.1 - 0.0022 17.8 0.0 0.23 11.3 0.0 2.3 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.19 EIW80915.1 - 0.097 12.8 0.0 0.6 10.3 0.0 2.1 2 1 0 2 2 2 0 PDZ domain (Also known as DHR or GLGF) BTB PF00651.26 EIW80916.1 - 2.2e-06 27.6 0.1 0.052 13.5 0.0 3.1 3 0 0 3 3 3 2 BTB/POZ domain COesterase PF00135.23 EIW80917.1 - 3.4e-93 313.1 2.3 4.4e-93 312.8 1.6 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW80917.1 - 1.1e-07 31.6 0.6 7.8e-07 28.8 0.4 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIW80917.1 - 0.043 13.0 0.3 0.09 11.9 0.2 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family RRM_1 PF00076.17 EIW80918.1 - 1.5e-45 152.7 0.3 3.9e-20 71.2 0.1 5.9 4 1 1 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW80918.1 - 1.1e-40 137.4 0.0 3.6e-15 55.6 0.0 5.4 4 1 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW80918.1 - 1.1e-18 66.8 0.2 2.9e-07 30.2 0.0 4.9 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Suf PF05843.9 EIW80918.1 - 3e-07 30.4 0.1 2e-06 27.7 0.0 2.2 2 0 0 2 2 2 1 Suppressor of forked protein (Suf) Nup35_RRM_2 PF14605.1 EIW80918.1 - 0.00022 20.9 0.0 6.5 6.6 0.0 4.5 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EIW80918.1 - 0.00063 19.5 0.2 0.01 15.6 0.1 3.0 4 0 0 4 4 4 1 RNA binding motif TPR_14 PF13428.1 EIW80918.1 - 0.18 12.5 9.6 16 6.4 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF4131 PF13567.1 EIW80919.1 - 3.7 6.9 14.1 1.4e+02 1.7 8.3 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) F-box-like PF12937.2 EIW80920.1 - 9.4e-08 31.6 3.4 2.5e-07 30.2 2.3 1.8 1 0 0 1 1 1 1 F-box-like Ribosomal_L31 PF01197.13 EIW80922.1 - 0.049 13.6 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L31 CTP_transf_1 PF01148.15 EIW80922.1 - 9 5.8 13.8 2 7.9 5.4 2.1 1 1 1 2 2 2 0 Cytidylyltransferase family FAD_binding_2 PF00890.19 EIW80923.1 - 9.8e-48 163.0 1.9 1.2e-46 159.4 1.3 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIW80923.1 - 5.4e-10 38.6 2.3 3.8e-06 26.0 0.1 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EIW80923.1 - 7.2e-09 35.2 1.3 4.1e-07 29.4 0.9 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EIW80923.1 - 3.3e-07 29.5 1.5 3.3e-07 29.5 1.0 2.4 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EIW80923.1 - 2.9e-06 27.2 0.5 0.00011 22.1 0.2 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW80923.1 - 0.00019 21.3 1.2 0.00059 19.8 0.8 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIW80923.1 - 0.00038 20.8 0.5 0.078 13.3 0.3 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIW80923.1 - 0.0019 17.1 0.2 0.0032 16.4 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EIW80923.1 - 0.0041 15.6 6.3 0.0046 15.4 0.3 2.8 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.1 EIW80923.1 - 0.011 15.7 0.0 0.027 14.5 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.14 EIW80923.1 - 0.021 13.9 0.0 4.3 6.4 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase FAD_binding_3 PF01494.14 EIW80923.1 - 0.039 12.9 0.2 0.099 11.6 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 EIW80923.1 - 0.1 11.7 0.3 0.56 9.2 0.1 2.1 2 0 0 2 2 2 0 Thi4 family PX PF00787.19 EIW80924.1 - 1e-14 54.2 2.5 4.6e-12 45.7 0.1 3.6 3 0 0 3 3 3 2 PX domain PLDc_2 PF13091.1 EIW80924.1 - 3.8e-13 49.2 0.0 5.1e-07 29.4 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EIW80924.1 - 3.1e-12 45.8 0.9 4.3e-05 23.1 0.0 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PH PF00169.24 EIW80924.1 - 0.002 18.2 0.0 0.014 15.6 0.0 2.3 1 1 0 1 1 1 1 PH domain PROCN PF08083.6 EIW80925.1 - 4.7e-220 730.1 7.4 7.3e-219 726.2 4.9 2.2 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EIW80925.1 - 7.8e-127 421.2 0.5 1.3e-126 420.5 0.3 1.4 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EIW80925.1 - 2.1e-92 306.7 1.2 5.6e-92 305.3 0.8 1.8 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EIW80925.1 - 2.1e-79 264.4 2.0 2.1e-79 264.4 1.4 2.7 3 0 0 3 3 3 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EIW80925.1 - 1.9e-69 231.5 0.1 3.8e-69 230.5 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 EIW80925.1 - 5.3e-43 144.8 0.1 1.2e-42 143.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 EIW80925.1 - 2.7e-36 124.0 0.0 7.1e-36 122.6 0.0 1.8 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.16 EIW80925.1 - 0.00057 19.6 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PH PF00169.24 EIW80926.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 PH domain DUF837 PF05769.6 EIW80927.1 - 0.0037 16.8 11.1 0.041 13.4 3.3 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF837) Acetyltransf_3 PF13302.1 EIW80931.1 - 3.4e-07 30.5 0.0 5.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW80931.1 - 1.7e-05 24.7 0.0 4.3e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF4098 PF13345.1 EIW80932.1 - 7.5e-06 25.8 6.5 0.00058 19.7 0.1 3.2 3 1 0 3 3 3 2 Domain of unknown function (DUF4098) F-actin_cap_A PF01267.12 EIW80933.1 - 7.3e-92 307.2 0.1 8.4e-92 307.0 0.1 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit F_actin_cap_B PF01115.12 EIW80933.1 - 0.0018 17.5 0.3 0.0028 16.9 0.2 1.3 1 0 0 1 1 1 1 F-actin capping protein, beta subunit ICL PF00463.16 EIW80934.1 - 2.3e-242 804.9 0.1 2.5e-242 804.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EIW80934.1 - 1.9e-08 33.8 0.0 3.1e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 EIW80934.1 - 0.06 12.8 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Glycos_transf_4 PF00953.16 EIW80935.1 - 2.9e-30 105.1 7.4 2.9e-30 105.1 5.1 2.3 3 0 0 3 3 3 1 Glycosyl transferase family 4 Malic_M PF03949.10 EIW80936.1 - 1.6e-79 267.0 0.0 2e-79 266.7 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EIW80936.1 - 8.4e-66 221.0 0.0 1.7e-65 220.0 0.0 1.5 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain MRP-L20 PF12824.2 EIW80937.1 - 3.4e-26 92.1 9.6 6.7e-26 91.2 6.7 1.4 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 EIW80937.1 - 1.5e-05 24.9 0.3 2.3e-05 24.3 0.2 1.3 1 0 0 1 1 1 1 Neugrin Metal_resist PF13801.1 EIW80937.1 - 0.27 11.2 4.6 0.42 10.5 0.7 2.3 2 0 0 2 2 2 0 Heavy-metal resistance FAP PF07174.6 EIW80937.1 - 0.52 9.5 9.5 0.65 9.2 6.6 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) GST_N_3 PF13417.1 EIW80938.1 - 1.5e-10 41.1 0.0 2.5e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW80938.1 - 2.6e-10 40.3 0.0 4.7e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW80938.1 - 2.8e-08 33.6 0.0 6.1e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW80938.1 - 1.5e-07 31.3 0.0 3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW80938.1 - 2.9e-06 27.0 0.0 6.4e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW80938.1 - 0.053 13.9 0.0 0.08 13.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Fcf2 PF08698.6 EIW80939.1 - 5e-18 64.9 0.0 4.2e-17 61.9 0.0 2.4 2 2 0 2 2 2 1 Fcf2 pre-rRNA processing SHS2_FTSA PF02491.15 EIW80939.1 - 0.03 14.1 0.1 14 5.6 0.0 2.8 2 1 0 2 2 2 0 SHS2 domain inserted in FTSA Cwf_Cwc_15 PF04889.7 EIW80939.1 - 0.47 10.1 16.1 0.17 11.5 6.9 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein GEMIN8 PF15348.1 EIW80939.1 - 0.77 9.7 4.5 1.5 8.8 3.1 1.4 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Ubie_methyltran PF01209.13 EIW80940.1 - 1.7e-78 262.9 0.0 2.2e-78 262.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EIW80940.1 - 9.6e-13 47.9 0.0 1.7e-12 47.1 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW80940.1 - 1.1e-10 41.5 0.0 1.8e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW80940.1 - 7.4e-10 39.1 0.0 1.5e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW80940.1 - 2.2e-09 37.6 0.0 5e-09 36.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW80940.1 - 3.2e-09 37.1 0.0 6e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW80940.1 - 1.8e-05 25.3 0.0 3.6e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW80940.1 - 0.0082 16.1 0.0 0.033 14.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Cullin PF00888.17 EIW80941.1 - 2.4e-190 633.9 15.8 3.2e-190 633.5 10.9 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EIW80941.1 - 1.7e-25 88.6 2.7 5.2e-25 87.0 1.9 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF1727 PF08353.5 EIW80941.1 - 0.014 15.0 0.0 0.054 13.1 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1727) AphA_like PF14557.1 EIW80941.1 - 0.041 13.4 0.0 4.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Putative AphA-like transcriptional regulator Rrf2 PF02082.15 EIW80941.1 - 0.14 12.2 0.7 0.5 10.5 0.4 2.0 2 0 0 2 2 2 0 Transcriptional regulator KAT11 PF08214.6 EIW80942.1 - 8e-31 107.3 0.0 1.6e-30 106.3 0.0 1.5 1 1 0 1 1 1 1 Histone acetylation protein Zn_clus PF00172.13 EIW80944.1 - 4.2e-06 26.5 7.0 7.4e-06 25.7 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EIW80944.1 - 7.4e-06 25.0 0.2 0.00029 19.8 0.1 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Tom22 PF04281.8 EIW80945.1 - 3.6e-40 136.6 0.9 4.4e-40 136.3 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 NAD_binding_10 PF13460.1 EIW80946.1 - 5.9e-19 68.7 0.0 9e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EIW80946.1 - 3.5e-13 49.3 0.0 4.8e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EIW80946.1 - 5.6e-13 48.4 0.0 6.2e-11 41.7 0.0 2.5 1 1 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EIW80946.1 - 7.3e-10 38.0 0.1 1.8e-08 33.4 0.1 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIW80946.1 - 5.8e-09 35.7 0.2 2.1e-07 30.6 0.1 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EIW80946.1 - 1.7e-07 30.4 0.3 0.0021 17.0 0.1 3.1 1 1 1 2 2 2 2 Male sterility protein Saccharop_dh PF03435.13 EIW80946.1 - 0.011 14.7 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF2462 PF09495.5 EIW80947.1 - 3.8e-18 65.9 12.8 4.1e-18 65.8 8.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2462) AOX PF01786.12 EIW80948.1 - 2.4e-88 294.9 0.0 2.9e-88 294.6 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase UPF0054 PF02130.12 EIW80948.1 - 0.068 12.4 0.0 3 7.1 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein family UPF0054 PH_4 PF15404.1 EIW80949.1 - 1.1e-30 106.5 0.6 1e-27 96.9 0.1 3.3 2 1 0 2 2 2 1 Pleckstrin homology domain zf-Nse PF11789.3 EIW80950.1 - 6.4e-15 54.4 0.0 1.1e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 EIW80950.1 - 9.5e-05 22.2 0.2 0.003 17.4 0.0 2.6 2 1 1 3 3 3 1 U-box domain Endosulfine PF04667.12 EIW80950.1 - 0.043 13.7 0.1 0.074 13.0 0.1 1.4 1 0 0 1 1 1 0 cAMP-regulated phosphoprotein/endosulfine conserved region zf-C3HC4 PF00097.20 EIW80950.1 - 0.079 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ribosom_S12_S23 PF00164.20 EIW80951.1 - 6.6e-44 148.2 4.5 1.9e-43 146.7 1.0 2.1 2 0 0 2 2 2 2 Ribosomal protein S12/S23 Complex1_LYR PF05347.10 EIW80952.1 - 0.011 15.4 0.5 0.076 12.8 0.3 2.0 1 1 0 1 1 1 0 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EIW80952.1 - 0.14 12.4 0.8 0.43 10.8 0.5 1.8 1 1 0 1 1 1 0 Complex1_LYR-like SQS_PSY PF00494.14 EIW80953.1 - 7.1e-48 163.2 0.1 9e-48 162.8 0.1 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase HTH_15 PF12324.3 EIW80953.1 - 0.017 14.7 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain of alkylmercury lyase vATP-synt_AC39 PF01992.11 EIW80955.1 - 1.3e-100 336.7 0.0 1.5e-100 336.6 0.0 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit EHN PF06441.7 EIW80956.1 - 1.9e-34 117.9 0.0 1.7e-33 114.8 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EIW80956.1 - 6.7e-08 32.6 0.2 1.2e-07 31.8 0.1 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW80956.1 - 6.1e-05 22.6 0.0 7.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold CRAL_TRIO PF00650.15 EIW80957.1 - 3.5e-26 91.5 0.0 5.5e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EIW80957.1 - 3.3e-11 43.1 0.0 1.4e-10 41.1 0.0 2.1 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain zf-CCHC_3 PF13917.1 EIW80959.1 - 1.7e-19 69.2 0.2 2.3e-19 68.8 0.2 1.2 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EIW80959.1 - 0.0095 15.8 1.0 0.015 15.2 0.7 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.1 EIW80959.1 - 0.032 13.7 0.2 0.05 13.0 0.2 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.1 EIW80959.1 - 0.041 13.3 0.2 0.071 12.6 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 EIW80959.1 - 0.047 13.7 0.2 0.065 13.3 0.1 1.2 1 0 0 1 1 1 0 DnaJ central domain ATP-synt_C PF00137.16 EIW80960.1 - 8.5e-26 89.6 29.2 7e-16 57.8 4.9 2.0 2 0 0 2 2 2 2 ATP synthase subunit C Ribosomal_L6 PF00347.18 EIW80961.1 - 3.7e-27 94.6 0.0 1.2e-12 48.1 0.0 2.3 2 0 0 2 2 2 2 Ribosomal protein L6 AA_permease_2 PF13520.1 EIW80962.1 - 1.3e-53 182.0 51.5 1.6e-53 181.7 35.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIW80962.1 - 5.5e-14 51.3 49.0 8.2e-14 50.7 34.0 1.2 1 0 0 1 1 1 1 Amino acid permease tRNA_bind PF01588.15 EIW80963.1 - 3.2e-29 100.6 0.0 6.9e-29 99.5 0.0 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 EIW80963.1 - 2.3e-05 24.7 0.0 6.3e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW80963.1 - 7.3e-05 22.6 0.3 0.00018 21.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIW80963.1 - 0.0042 16.9 0.0 0.0095 15.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain RR_TM4-6 PF06459.7 EIW80963.1 - 0.97 9.2 5.4 1.3 8.8 3.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DIOX_N PF14226.1 EIW80964.1 - 4.6e-24 85.1 0.0 6.6e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIW80964.1 - 2.4e-12 47.0 0.0 5.2e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CBFD_NFYB_HMF PF00808.18 EIW80965.1 - 8.3e-09 35.3 0.0 1.4e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Diphtheria_C PF02763.9 EIW80965.1 - 0.038 13.4 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Diphtheria toxin, C domain Histone PF00125.19 EIW80965.1 - 0.045 13.8 0.1 0.083 13.0 0.1 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Soyouz_module PF14313.1 EIW80965.1 - 0.047 13.2 0.3 0.047 13.2 0.2 2.5 3 0 0 3 3 3 0 N-terminal region of Paramyxovirinae phosphoprotein (P) HSP20 PF00011.16 EIW80966.1 - 3e-15 55.9 0.1 3.2e-09 36.5 0.0 2.1 1 1 0 2 2 2 2 Hsp20/alpha crystallin family DUF1325 PF07039.6 EIW80967.1 - 7e-34 116.2 0.0 1.1e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 SGF29 tudor-like domain Agenet PF05641.7 EIW80967.1 - 0.036 14.2 0.2 1.2 9.3 0.0 3.0 3 0 0 3 3 3 0 Agenet domain Vps53_N PF04100.7 EIW80967.1 - 0.13 10.9 0.3 0.18 10.5 0.2 1.1 1 0 0 1 1 1 0 Vps53-like, N-terminal Translin PF01997.11 EIW80968.1 - 1.7e-41 142.0 0.0 2e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Translin family DUF1664 PF07889.7 EIW80968.1 - 0.028 14.2 0.1 0.048 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Med4 PF10018.4 EIW80968.1 - 0.1 11.9 0.4 0.15 11.4 0.3 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 FliT PF05400.8 EIW80968.1 - 0.53 10.7 3.9 0.68 10.3 1.9 1.7 2 0 0 2 2 2 0 Flagellar protein FliT SEN1_N PF12726.2 EIW80969.1 - 5.1e-121 405.0 0.0 6.9e-121 404.6 0.0 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EIW80969.1 - 2.2e-66 223.8 1.3 3.7e-66 223.0 0.9 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.1 EIW80969.1 - 1.2e-57 194.4 0.0 2.6e-57 193.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW80969.1 - 3.7e-09 36.2 0.2 1.1e-08 34.6 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EIW80969.1 - 7.4e-09 35.4 0.1 0.00033 20.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EIW80969.1 - 0.0075 15.8 1.4 0.23 10.9 0.1 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DEAD PF00270.24 EIW80969.1 - 0.008 15.6 0.1 0.037 13.5 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase CCDC144C PF14915.1 EIW80969.1 - 0.02 13.8 5.1 0.062 12.2 3.3 1.9 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region ResIII PF04851.10 EIW80969.1 - 0.02 14.7 0.1 0.19 11.5 0.1 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit PHA-1 PF06542.6 EIW80969.1 - 0.021 13.5 0.0 0.035 12.8 0.0 1.2 1 0 0 1 1 1 0 Regulator protein PHA-1 AAA_25 PF13481.1 EIW80969.1 - 0.027 13.9 0.1 0.16 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain HCMV_UL139 PF12507.3 EIW80969.1 - 0.027 14.6 0.5 0.027 14.6 0.3 2.1 2 0 0 2 2 1 0 Human Cytomegalovirus UL139 protein Helicase_RecD PF05127.9 EIW80969.1 - 0.06 12.9 1.2 1.2 8.7 0.0 2.6 1 1 1 2 2 2 0 Helicase AAA_23 PF13476.1 EIW80969.1 - 0.079 13.2 0.2 0.18 12.0 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EIW80969.1 - 0.11 12.6 0.4 1.6 8.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EIW80969.1 - 0.15 12.2 0.5 0.84 9.8 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) GrpE PF01025.14 EIW80969.1 - 0.19 11.2 5.3 5.7 6.4 0.0 3.1 3 1 0 3 3 3 0 GrpE TMF_DNA_bd PF12329.3 EIW80969.1 - 0.38 10.5 9.5 0.068 12.9 0.5 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding HA2 PF04408.18 EIW80970.1 - 3.6e-20 71.8 0.0 1.2e-19 70.1 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EIW80970.1 - 2.3e-18 66.0 0.0 4.9e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EIW80970.1 - 4.5e-14 52.0 0.1 1.8e-12 46.9 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIW80970.1 - 4.2e-06 26.3 1.3 6.8e-06 25.6 0.0 2.0 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EIW80970.1 - 7.4e-06 26.1 0.0 2.7e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EIW80970.1 - 0.00072 19.9 4.0 0.047 14.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain ResIII PF04851.10 EIW80970.1 - 0.011 15.6 1.4 0.2 11.4 0.0 3.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit Scm3 PF10384.4 EIW80971.1 - 2e-11 43.2 0.2 3.9e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 Centromere protein Scm3 Striatin PF08232.7 EIW80971.1 - 9.5 6.5 12.2 10 6.4 0.1 3.4 3 0 0 3 3 3 0 Striatin family PP2C PF00481.16 EIW80972.1 - 1e-78 264.2 0.0 1e-78 264.2 0.0 1.4 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 EIW80972.1 - 0.0041 16.5 0.0 0.012 15.0 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C Transposase_21 PF02992.9 EIW80973.1 - 6.4e-07 28.6 0.0 1.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EIW80973.1 - 3.9e-05 23.1 0.1 0.00011 21.6 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4218) CCER1 PF15482.1 EIW80973.1 - 0.026 14.1 0.2 0.053 13.1 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 HMG_box PF00505.14 EIW80974.1 - 0.042 14.1 0.1 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 HMG (high mobility group) box DUF972 PF06156.8 EIW80974.1 - 0.11 12.8 0.2 1.7 9.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) zf-ribbon_3 PF13248.1 EIW80975.1 - 0.1 11.8 3.9 0.18 11.0 2.7 1.5 1 0 0 1 1 1 0 zinc-ribbon domain PolC_DP2 PF03833.8 EIW80975.1 - 0.71 7.4 2.7 0.76 7.3 1.9 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-MYND PF01753.13 EIW80975.1 - 0.94 9.4 10.8 1.7 8.5 7.5 1.4 1 0 0 1 1 1 0 MYND finger zf-HIT PF04438.11 EIW80975.1 - 1.6 8.3 10.0 0.38 10.4 4.3 2.0 2 1 0 2 2 2 0 HIT zinc finger BUD22 PF09073.5 EIW80976.1 - 2e-63 214.9 13.9 2e-63 214.9 9.7 1.5 2 0 0 2 2 2 1 BUD22 TFCD_C PF12612.3 EIW80977.1 - 1.4e-35 122.5 3.2 1.7e-34 118.9 0.1 3.6 3 1 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 EIW80977.1 - 6e-07 29.0 17.9 0.026 14.6 0.0 8.6 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.1 EIW80977.1 - 1.6e-05 25.1 19.4 0.19 12.0 0.0 7.8 6 2 2 8 8 8 3 HEAT repeats HEAT_EZ PF13513.1 EIW80977.1 - 5.7e-05 23.4 16.1 0.11 12.9 0.0 7.8 7 0 0 7 7 7 2 HEAT-like repeat ATP-synt_ab PF00006.20 EIW80978.1 - 1.3e-61 207.8 0.0 1.9e-61 207.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EIW80978.1 - 1.2e-16 61.2 0.1 2.5e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EIW80978.1 - 2.3e-11 43.7 0.4 4.5e-11 42.8 0.3 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EIW80978.1 - 0.00068 19.4 0.3 0.0016 18.3 0.2 1.5 1 0 0 1 1 1 1 HAS barrel domain Tcp11 PF05794.8 EIW80979.1 - 5.6e-45 153.8 0.0 2.6e-43 148.3 0.0 2.9 1 1 0 1 1 1 1 T-complex protein 11 GPI-anchored PF10342.4 EIW80980.1 - 2.8e-07 30.9 0.2 3.7e-07 30.5 0.1 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EIW80980.1 - 0.028 13.9 0.0 0.034 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) CMAS PF02353.15 EIW80982.1 - 1.9e-53 181.3 0.2 3.5e-41 141.0 0.0 2.1 2 0 0 2 2 2 2 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EIW80982.1 - 3.5e-08 34.0 0.0 7e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW80982.1 - 2.8e-06 27.1 0.0 5.5e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW80982.1 - 4.5e-05 23.8 0.0 9.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW80982.1 - 0.0012 18.2 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EIW80982.1 - 0.0019 17.7 0.0 0.0042 16.5 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase RrnaAD PF00398.15 EIW80982.1 - 0.0059 15.6 0.1 0.092 11.7 0.0 2.4 2 1 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.7 EIW80982.1 - 0.0094 16.4 0.0 0.027 14.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW80982.1 - 0.017 14.7 0.0 0.032 13.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 EIW80982.1 - 0.018 14.5 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_24 PF13578.1 EIW80982.1 - 0.043 14.6 0.0 0.1 13.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.12 EIW80982.1 - 0.062 12.3 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_4 PF02390.12 EIW80982.1 - 0.072 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DOT1 PF08123.8 EIW80982.1 - 0.086 12.1 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Met_10 PF02475.11 EIW80982.1 - 0.088 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein EBP PF05241.7 EIW80984.1 - 7.5e-59 198.0 9.6 9.2e-59 197.7 6.7 1.0 1 0 0 1 1 1 1 Emopamil binding protein UPF0172 PF03665.8 EIW80985.1 - 8.7e-44 149.3 0.0 1.7e-43 148.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) Amidohydro_1 PF01979.15 EIW80985.1 - 8e-24 84.8 0.0 1.4e-23 84.1 0.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EIW80985.1 - 0.0025 17.1 0.7 0.0054 15.9 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 EIW80985.1 - 0.023 14.7 0.1 0.22 11.5 0.0 2.2 2 0 0 2 2 2 0 Amidohydrolase A_deaminase PF00962.17 EIW80985.1 - 0.093 11.6 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Adenosine/AMP deaminase Mon1 PF03164.9 EIW80986.1 - 3.1e-107 358.7 0.0 2.5e-70 237.1 0.0 2.0 2 0 0 2 2 2 2 Trafficking protein Mon1 IGR PF09597.5 EIW80987.1 - 1.5e-14 53.6 0.0 2.1e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 IGR protein motif FHA PF00498.21 EIW80989.1 - 1.3e-15 57.2 0.1 2.2e-15 56.5 0.1 1.4 1 0 0 1 1 1 1 FHA domain DUF1777 PF08648.7 EIW80989.1 - 0.016 14.9 27.4 0.028 14.1 19.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 EIW80989.1 - 0.14 10.5 4.3 0.13 10.6 3.0 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Atrophin-1 PF03154.10 EIW80989.1 - 2 6.4 7.7 2.5 6.1 5.4 1.1 1 0 0 1 1 1 0 Atrophin-1 family Lipase_3 PF01764.20 EIW80990.1 - 3.1e-21 75.4 0.0 4.7e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.8 EIW80990.1 - 0.0083 15.7 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_1 PF00561.15 EIW80990.1 - 0.013 15.0 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIW80990.1 - 0.016 15.0 1.1 0.028 14.3 0.1 1.6 1 1 0 2 2 2 0 Alpha/beta hydrolase family DUF2974 PF11187.3 EIW80990.1 - 0.13 11.5 0.2 0.44 9.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) UPF0227 PF05728.7 EIW80990.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Zn_clus PF00172.13 EIW80991.1 - 3.3e-08 33.3 11.5 3.3e-08 33.3 8.0 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EIW80991.1 - 0.0093 14.8 1.0 0.061 12.1 0.7 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C3HC4_2 PF13923.1 EIW80992.1 - 1.6e-06 27.9 11.6 1.6e-06 27.9 8.0 3.9 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW80992.1 - 1.5e-05 24.5 7.6 1.5e-05 24.5 5.2 3.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW80992.1 - 1.6e-05 24.5 10.5 1.6e-05 24.5 7.3 3.3 3 1 1 4 4 4 1 Ring finger domain zf-RING_6 PF14835.1 EIW80992.1 - 3e-05 23.7 5.4 3e-05 23.7 3.8 2.3 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 EIW80992.1 - 0.00011 21.7 7.3 0.00011 21.7 5.1 3.5 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW80992.1 - 0.00029 20.5 9.2 0.00029 20.5 6.4 3.1 3 0 0 3 3 3 1 zinc-RING finger domain zf-rbx1 PF12678.2 EIW80992.1 - 0.012 15.7 4.0 0.012 15.7 2.7 2.8 2 1 1 3 3 3 0 RING-H2 zinc finger PolyA_pol_RNAbd PF12627.2 EIW80992.1 - 0.15 11.6 0.0 0.35 10.4 0.0 1.5 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A zf-Apc11 PF12861.2 EIW80992.1 - 0.97 9.3 10.5 0.068 13.0 1.6 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Kelch_6 PF13964.1 EIW80993.1 - 1.7e-20 72.2 0.8 0.00017 21.6 0.0 4.9 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.1 EIW80993.1 - 2.3e-19 68.8 7.4 1.1e-05 25.0 0.1 4.9 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EIW80993.1 - 1.8e-15 56.1 0.0 0.0001 21.7 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 EIW80993.1 - 8.6e-15 53.8 3.9 0.00024 20.7 0.0 5.3 5 1 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 EIW80993.1 - 8.4e-14 51.1 0.2 0.0019 18.1 0.0 5.0 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 EIW80993.1 - 1e-13 50.9 2.5 3.8e-05 23.7 0.0 5.5 5 0 0 5 5 5 3 Galactose oxidase, central domain Pyridox_oxidase PF01243.15 EIW80994.1 - 4.3e-23 81.1 0.0 6.7e-23 80.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNPOx_C PF10590.4 EIW80994.1 - 7.9e-18 63.6 3.7 1.4e-17 62.8 2.6 1.4 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.2 EIW80994.1 - 4.7e-06 26.8 0.0 8.1e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase E1-E2_ATPase PF00122.15 EIW80995.1 - 4e-61 205.9 1.7 4e-61 205.9 1.2 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EIW80995.1 - 7.6e-32 111.4 0.0 2.3e-31 109.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EIW80995.1 - 4e-22 78.6 20.4 5.1e-18 65.2 0.8 4.1 4 0 0 4 4 4 2 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 EIW80995.1 - 7.6e-19 67.4 0.0 1.6e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EIW80995.1 - 1.6e-14 54.5 0.0 4.1e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIW80995.1 - 9.7e-13 47.3 0.0 2.1e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIW80995.1 - 0.00018 21.2 0.6 0.03 13.8 0.3 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF4064 PF13273.1 EIW80995.1 - 1.5 8.9 10.1 6.3 6.9 2.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Glycolytic PF00274.14 EIW80996.1 - 6.8e-76 254.9 0.0 8.3e-76 254.6 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Linker_histone PF00538.14 EIW80998.1 - 4e-07 30.0 0.0 6.9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 linker histone H1 and H5 family Ecl1 PF12855.2 EIW81000.1 - 0.00012 21.2 2.5 0.06 12.6 0.0 2.8 3 0 0 3 3 3 2 Life-span regulatory factor OGFr_N PF04664.8 EIW81001.1 - 1.3e-42 145.5 1.1 1e-41 142.6 0.8 2.3 1 1 1 2 2 2 1 Opioid growth factor receptor (OGFr) conserved region HLH PF00010.21 EIW81001.1 - 0.085 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-loop-helix DNA-binding domain Sec1 PF00995.18 EIW81002.1 - 2.4e-136 455.6 0.0 2.7e-136 455.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family COPIIcoated_ERV PF07970.7 EIW81003.1 - 6e-65 218.9 0.5 8.5e-65 218.4 0.3 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EIW81003.1 - 6.5e-31 106.1 1.6 7e-31 106.0 0.1 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Peptidase_S9 PF00326.16 EIW81007.1 - 2.8e-37 128.0 0.0 5.5e-37 127.0 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIW81007.1 - 5.8e-07 29.3 0.0 1.2e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW81007.1 - 0.00031 20.6 1.0 0.003 17.4 0.4 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.8 EIW81007.1 - 0.026 13.9 0.0 0.069 12.5 0.0 1.7 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PhoPQ_related PF10142.4 EIW81007.1 - 0.075 11.4 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Abhydrolase_2 PF02230.11 EIW81007.1 - 0.13 11.7 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EIW81008.1 - 8.6e-48 162.3 0.1 1.5e-47 161.6 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIW81008.1 - 1.1e-09 38.2 0.0 2.8e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family APG6 PF04111.7 EIW81009.1 - 1.8 7.5 9.8 4.2 6.3 6.8 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 Adaptin_binding PF10199.4 EIW81011.1 - 1.9e-07 31.4 1.0 5.2e-06 26.7 0.7 2.5 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 HEAT_2 PF13646.1 EIW81013.1 - 7.6e-49 163.9 13.1 5.8e-16 58.5 0.1 3.9 2 2 4 6 6 6 6 HEAT repeats HEAT_PBS PF03130.11 EIW81013.1 - 2.2e-23 80.2 8.0 0.00018 21.6 0.1 7.0 7 0 0 7 7 7 4 PBS lyase HEAT-like repeat HEAT PF02985.17 EIW81013.1 - 2.3e-12 45.8 0.8 0.044 13.8 0.0 5.5 6 0 0 6 6 6 3 HEAT repeat HEAT_EZ PF13513.1 EIW81013.1 - 4.7e-11 42.8 2.1 0.0021 18.4 0.0 5.0 2 2 1 3 3 3 3 HEAT-like repeat Arm PF00514.18 EIW81013.1 - 5.8e-05 22.7 0.3 1.7 8.6 0.0 3.6 2 1 1 3 3 3 2 Armadillo/beta-catenin-like repeat Ribosomal_L10 PF00466.15 EIW81014.1 - 1.2e-18 66.8 0.0 1.9e-18 66.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 O-antigen_lig PF13425.1 EIW81015.1 - 0.046 13.7 4.9 0.074 13.0 3.4 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein IncA PF04156.9 EIW81015.1 - 0.071 12.6 6.5 0.11 12.0 4.5 1.3 1 0 0 1 1 1 0 IncA protein NCA2 PF08637.5 EIW81016.1 - 6.7e-72 241.8 0.0 8.4e-72 241.4 0.0 1.0 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 MBOAT_2 PF13813.1 EIW81017.1 - 3.8e-11 42.8 1.9 3.8e-11 42.8 1.4 2.5 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family DUF2463 PF09591.5 EIW81017.1 - 0.089 12.3 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) Mod_r PF07200.8 EIW81018.1 - 3.4e-26 91.9 2.3 4.3e-26 91.6 1.6 1.1 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein RPAP1_N PF08621.5 EIW81018.1 - 0.09 12.3 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 RPAP1-like, N-terminal Rootletin PF15035.1 EIW81018.1 - 0.1 12.5 3.8 0.1 12.5 1.8 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion AAA PF00004.24 EIW81020.1 - 6.4e-41 139.6 0.0 1.2e-40 138.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIW81020.1 - 3.3e-05 23.9 0.2 0.002 18.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EIW81020.1 - 0.00034 20.7 0.5 0.019 15.1 0.3 2.5 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EIW81020.1 - 0.00086 18.4 0.0 0.0018 17.3 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EIW81020.1 - 0.0012 18.5 0.2 0.0085 15.8 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EIW81020.1 - 0.0019 18.1 0.1 0.024 14.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 EIW81020.1 - 0.0041 16.3 0.1 0.029 13.5 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein AAA_33 PF13671.1 EIW81020.1 - 0.005 16.7 0.2 0.022 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EIW81020.1 - 0.0075 15.7 0.1 0.015 14.7 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EIW81020.1 - 0.0084 15.8 0.2 0.021 14.5 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EIW81020.1 - 0.017 15.9 0.1 0.045 14.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EIW81020.1 - 0.017 14.2 0.0 0.037 13.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EIW81020.1 - 0.036 13.9 0.0 0.082 12.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EIW81020.1 - 0.039 13.3 1.1 0.51 9.7 0.1 2.6 1 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 EIW81020.1 - 0.042 12.7 0.0 0.07 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 EIW81020.1 - 0.069 12.7 0.1 0.23 11.0 0.1 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EIW81020.1 - 0.071 13.2 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase adh_short PF00106.20 EIW81022.1 - 1.3e-17 64.2 0.1 4.1e-17 62.5 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIW81022.1 - 3.2e-08 33.4 0.0 6.8e-08 32.3 0.0 1.5 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EIW81022.1 - 1.3e-06 28.3 0.0 3.8e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIW81022.1 - 0.00013 22.0 0.1 0.00024 21.1 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIW81022.1 - 0.00025 20.0 0.0 0.00037 19.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Shikimate_DH PF01488.15 EIW81022.1 - 0.00081 19.4 0.1 0.0014 18.7 0.1 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EIW81022.1 - 0.0075 15.7 0.1 0.01 15.2 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIW81022.1 - 0.023 13.3 0.0 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EIW81022.1 - 0.033 13.1 0.0 0.044 12.6 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein THF_DHG_CYH_C PF02882.14 EIW81022.1 - 0.055 12.5 0.0 0.099 11.7 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NmrA PF05368.8 EIW81022.1 - 0.081 12.1 0.1 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 NmrA-like family TIR-like PF10137.4 EIW81022.1 - 0.082 12.5 0.2 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Predicted nucleotide-binding protein containing TIR-like domain RasGEF PF00617.14 EIW81023.1 - 2.7e-52 177.2 0.0 1e-51 175.3 0.0 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EIW81023.1 - 1.1e-19 70.4 0.0 2.6e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_9 PF14604.1 EIW81023.1 - 1.1e-13 50.5 0.0 2e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIW81023.1 - 1.1e-12 47.1 0.0 2e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIW81023.1 - 2.2e-12 46.2 0.0 4.1e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Miro PF08477.8 EIW81024.1 - 9.5e-36 122.9 0.0 9.9e-19 67.9 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 EIW81024.1 - 4.7e-35 119.2 0.0 9.2e-35 118.2 0.0 1.5 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 EIW81024.1 - 1.5e-31 108.9 0.0 7.3e-20 70.9 0.0 2.2 2 0 0 2 2 2 2 Ras family EF_assoc_1 PF08355.7 EIW81024.1 - 2.1e-30 103.7 0.3 4.4e-30 102.7 0.2 1.5 1 0 0 1 1 1 1 EF hand associated Arf PF00025.16 EIW81024.1 - 7.8e-11 41.5 0.0 3e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family EF-hand_6 PF13405.1 EIW81024.1 - 2.3e-08 33.2 1.3 0.0078 16.0 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain MMR_HSR1 PF01926.18 EIW81024.1 - 3.4e-08 33.4 0.0 0.002 18.0 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 EIW81024.1 - 4.2e-08 33.3 0.0 0.0047 17.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain EF-hand_1 PF00036.27 EIW81024.1 - 1.5e-06 27.1 4.9 0.012 14.9 0.0 2.9 3 0 0 3 3 2 2 EF hand AAA_28 PF13521.1 EIW81024.1 - 1.5e-06 28.2 0.0 0.016 15.1 0.0 3.2 2 1 0 2 2 2 2 AAA domain MobB PF03205.9 EIW81024.1 - 2.6e-06 27.1 0.1 0.065 12.9 0.0 2.3 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B EF-hand_7 PF13499.1 EIW81024.1 - 3.8e-06 26.9 0.3 0.21 11.7 0.0 3.1 3 0 0 3 3 2 2 EF-hand domain pair AAA_16 PF13191.1 EIW81024.1 - 4.6e-06 26.7 0.0 0.065 13.2 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain EF-hand_5 PF13202.1 EIW81024.1 - 8.6e-06 24.8 6.2 0.0021 17.2 0.1 2.7 2 0 0 2 2 2 2 EF hand Dynamin_N PF00350.18 EIW81024.1 - 8.7e-06 25.6 1.1 0.34 10.6 0.0 3.2 2 1 1 3 3 3 2 Dynamin family ABC_tran PF00005.22 EIW81024.1 - 2.5e-05 24.6 0.0 0.21 11.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 EIW81024.1 - 4e-05 23.0 0.1 0.042 13.3 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.24 EIW81024.1 - 8.3e-05 22.7 0.0 0.25 11.5 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 EIW81024.1 - 9.9e-05 21.6 0.0 0.082 12.1 0.0 2.5 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit NACHT PF05729.7 EIW81024.1 - 0.00014 21.6 0.0 0.17 11.4 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.1 EIW81024.1 - 0.0002 21.0 0.0 0.69 9.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EIW81024.1 - 0.00029 20.7 0.1 0.61 9.9 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EIW81024.1 - 0.00031 21.0 0.0 0.81 10.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EIW81024.1 - 0.00032 19.9 0.0 0.089 11.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EIW81024.1 - 0.00073 19.1 1.0 4.3 6.7 0.0 4.0 4 0 0 4 4 4 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EIW81024.1 - 0.00089 20.0 0.1 0.63 10.8 0.0 2.9 3 0 0 3 3 2 1 AAA domain Septin PF00735.13 EIW81024.1 - 0.00094 18.2 0.0 0.037 13.0 0.0 2.2 2 0 0 2 2 2 1 Septin PduV-EutP PF10662.4 EIW81024.1 - 0.001 18.5 0.0 0.17 11.4 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.13 EIW81024.1 - 0.0019 17.7 0.0 0.38 10.2 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 EIW81024.1 - 0.0024 18.2 0.1 0.96 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EIW81024.1 - 0.0025 17.5 0.1 0.52 9.9 0.0 2.2 2 0 0 2 2 2 1 Archaeal ATPase RNA_helicase PF00910.17 EIW81024.1 - 0.0026 17.9 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.8 EIW81024.1 - 0.0044 15.9 0.0 0.62 8.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) G-alpha PF00503.15 EIW81024.1 - 0.0049 15.5 0.1 2 6.9 0.0 2.8 3 0 0 3 3 3 1 G-protein alpha subunit GTP_EFTU PF00009.22 EIW81024.1 - 0.0056 16.1 0.0 2.1 7.7 0.0 3.6 4 0 0 4 4 4 1 Elongation factor Tu GTP binding domain EF-hand_10 PF14788.1 EIW81024.1 - 0.0057 16.2 2.2 0.093 12.4 0.1 2.4 2 0 0 2 2 2 1 EF hand FtsK_SpoIIIE PF01580.13 EIW81024.1 - 0.0063 16.0 0.1 2.6 7.4 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_25 PF13481.1 EIW81024.1 - 0.0067 15.8 0.0 0.83 9.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain EF-hand_8 PF13833.1 EIW81024.1 - 0.013 15.1 0.3 1.7 8.3 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain pair ATP-synt_ab PF00006.20 EIW81024.1 - 0.025 14.0 0.0 0.2 11.1 0.0 2.1 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Gtr1_RagA PF04670.7 EIW81024.1 - 0.027 13.6 0.0 3.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region AAA_14 PF13173.1 EIW81024.1 - 0.028 14.2 0.0 11 5.8 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EIW81024.1 - 0.029 14.0 0.0 1 9.0 0.0 2.6 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) cobW PF02492.14 EIW81024.1 - 0.045 13.1 0.1 2.9 7.3 0.0 2.8 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain MCM PF00493.18 EIW81024.1 - 0.045 12.5 0.0 0.18 10.5 0.0 1.8 2 0 0 2 2 2 0 MCM2/3/5 family AAA_15 PF13175.1 EIW81024.1 - 0.056 12.4 0.0 9.6 5.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 EIW81024.1 - 0.06 12.4 0.0 6.6 5.7 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin VirE PF05272.6 EIW81024.1 - 0.061 12.7 0.1 4.5 6.6 0.0 2.8 3 0 0 3 3 3 0 Virulence-associated protein E SPARC_Ca_bdg PF10591.4 EIW81024.1 - 0.081 12.9 0.1 5.6 7.0 0.0 2.7 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region NB-ARC PF00931.17 EIW81024.1 - 0.094 11.5 0.0 9.6 4.9 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain TrwB_AAD_bind PF10412.4 EIW81024.1 - 0.14 10.7 0.0 7.2 5.1 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AIG1 PF04548.11 EIW81024.1 - 0.16 11.0 0.0 0.34 9.9 0.0 1.6 2 0 0 2 2 1 0 AIG1 family Guanylate_kin PF00625.16 EIW81024.1 - 0.19 11.1 0.1 0.83 9.0 0.0 2.0 2 0 0 2 2 2 0 Guanylate kinase AAA_30 PF13604.1 EIW81024.1 - 0.23 11.0 0.0 2.6 7.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain VWA_2 PF13519.1 EIW81025.1 - 1.5e-11 44.6 0.0 3.1e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EIW81025.1 - 3.6e-05 23.5 0.0 6.1e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Med25_VWA PF11265.3 EIW81025.1 - 0.0096 14.9 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A G-patch PF01585.18 EIW81026.1 - 2.1 8.1 5.0 0.71 9.6 0.2 2.7 3 0 0 3 3 3 0 G-patch domain Receptor_2B4 PF11465.3 EIW81027.1 - 0.023 14.6 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 SRF-TF PF00319.13 EIW81028.1 - 1.2e-22 78.8 0.2 1.9e-22 78.1 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Methyltransf_23 PF13489.1 EIW81029.1 - 1.9e-09 37.4 0.0 4.1e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW81029.1 - 7.8e-09 35.9 0.0 1.9e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW81029.1 - 9.4e-09 35.5 0.0 1.8e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW81029.1 - 1.7e-06 28.3 0.0 3.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW81029.1 - 3e-06 27.7 0.0 8.3e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW81029.1 - 3.2e-06 26.4 0.0 5.1e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EIW81029.1 - 5e-06 26.1 0.0 1e-05 25.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW81029.1 - 5.9e-06 26.3 0.0 2e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIW81029.1 - 0.0095 15.0 0.0 0.033 13.2 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase CDC37_N PF03234.9 EIW81030.1 - 2e-47 161.7 0.2 3.5e-47 161.0 0.1 1.4 1 0 0 1 1 1 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EIW81030.1 - 1.1e-30 106.3 0.0 3e-30 104.9 0.0 1.6 2 0 0 2 2 2 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EIW81030.1 - 6.7e-18 64.3 2.4 8.8e-18 63.9 0.0 2.2 2 0 0 2 2 2 1 Cdc37 C terminal domain Striatin PF08232.7 EIW81030.1 - 0.018 15.3 5.7 0.47 10.7 0.5 2.7 3 0 0 3 3 3 0 Striatin family TRAP_alpha PF03896.11 EIW81031.1 - 0.1 11.5 0.1 0.16 10.9 0.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit MRJP PF03022.11 EIW81032.1 - 6.3e-34 117.4 0.0 8e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Major royal jelly protein CBM_6 PF03422.10 EIW81032.1 - 0.029 14.5 0.7 0.1 12.7 0.5 1.9 1 0 0 1 1 1 0 Carbohydrate binding module (family 6) NHL PF01436.16 EIW81032.1 - 0.079 12.9 5.3 21 5.3 0.1 4.8 4 0 0 4 4 4 0 NHL repeat SnoaL PF07366.7 EIW81033.1 - 1.6e-14 53.5 0.0 2.2e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EIW81033.1 - 6.4e-07 29.7 0.0 8.6e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain ABC_membrane PF00664.18 EIW81034.1 - 9.5e-89 297.4 28.7 2.5e-44 151.7 4.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIW81034.1 - 8.3e-68 226.9 0.2 2.4e-34 118.5 0.0 2.9 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 EIW81034.1 - 2.3e-14 53.1 0.1 9.1e-05 21.7 0.0 4.1 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIW81034.1 - 3.7e-13 50.0 0.0 0.00093 19.2 0.0 4.4 3 1 0 3 3 3 2 AAA domain ABC_ATPase PF09818.4 EIW81034.1 - 9.5e-10 37.6 1.8 0.00014 20.6 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EIW81034.1 - 2.7e-07 30.0 1.1 0.0026 17.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EIW81034.1 - 8.3e-07 29.1 1.2 0.0035 17.3 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_17 PF13207.1 EIW81034.1 - 2.4e-06 28.3 0.0 0.12 13.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EIW81034.1 - 1.2e-05 24.5 0.0 0.092 11.9 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 G-alpha PF00503.15 EIW81034.1 - 1.9e-05 23.5 0.1 0.029 13.0 0.0 2.5 2 1 0 2 2 2 2 G-protein alpha subunit AAA_30 PF13604.1 EIW81034.1 - 0.00013 21.5 1.4 0.64 9.5 0.1 4.2 2 2 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EIW81034.1 - 0.00017 21.3 2.3 0.68 9.8 0.1 3.2 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EIW81034.1 - 0.00018 21.8 0.4 1.2 9.4 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_25 PF13481.1 EIW81034.1 - 0.00022 20.6 0.2 0.36 10.2 0.0 3.3 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.1 EIW81034.1 - 0.00058 20.0 4.6 0.45 10.6 0.3 4.1 2 2 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EIW81034.1 - 0.002 18.0 0.0 2.7 7.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EIW81034.1 - 0.002 17.2 0.0 1.7 7.6 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA PF00004.24 EIW81034.1 - 0.002 18.3 0.9 3.2 7.9 0.2 4.0 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIW81034.1 - 0.0047 16.6 0.1 3.1 7.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EIW81034.1 - 0.0052 16.7 0.3 1.6 8.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIW81034.1 - 0.0062 16.2 0.1 3.7 7.3 0.0 3.1 2 0 0 2 2 2 1 Part of AAA domain ATP-synt_ab PF00006.20 EIW81034.1 - 0.0081 15.6 0.1 2.2 7.6 0.0 2.7 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_14 PF13173.1 EIW81034.1 - 0.01 15.7 0.1 4.5 7.1 0.0 3.6 4 0 0 4 4 3 0 AAA domain AAA_10 PF12846.2 EIW81034.1 - 0.012 15.0 1.0 12 5.2 0.0 3.4 4 0 0 4 4 3 0 AAA-like domain MMR_HSR1 PF01926.18 EIW81034.1 - 0.016 15.1 0.1 6.3 6.7 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase MobB PF03205.9 EIW81034.1 - 0.016 14.9 0.1 7 6.3 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.12 EIW81034.1 - 0.02 14.7 1.1 9.4 5.9 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 RNA_helicase PF00910.17 EIW81034.1 - 0.024 14.8 0.1 8 6.6 0.0 3.7 4 0 0 4 4 3 0 RNA helicase AAA_23 PF13476.1 EIW81034.1 - 0.029 14.6 3.3 2.3 8.4 0.1 2.9 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 EIW81034.1 - 0.035 14.5 0.0 15 6.0 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein DUF815 PF05673.8 EIW81034.1 - 0.039 12.8 0.0 6.4 5.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_15 PF13175.1 EIW81034.1 - 0.048 12.7 0.0 1.1 8.2 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain APS_kinase PF01583.15 EIW81034.1 - 0.05 13.2 0.1 1.4 8.5 0.0 2.8 3 0 0 3 3 3 0 Adenylylsulphate kinase NB-ARC PF00931.17 EIW81034.1 - 0.064 12.0 0.0 2.5 6.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain PRK PF00485.13 EIW81034.1 - 0.064 12.7 0.0 5.9 6.4 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Synapsin_N PF10581.4 EIW81034.1 - 0.093 12.5 0.0 4.9 7.0 0.0 2.6 2 0 0 2 2 2 0 Synapsin N-terminal CDC45 PF02724.9 EIW81034.1 - 1.5 6.7 4.9 0.28 9.1 0.9 1.5 2 0 0 2 2 2 0 CDC45-like protein ABC_membrane PF00664.18 EIW81035.1 - 2.1e-89 299.6 29.1 6.3e-45 153.7 10.4 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIW81035.1 - 7.3e-68 227.1 0.0 3.3e-34 118.1 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EIW81035.1 - 1.3e-13 50.7 0.0 2.3e-05 23.7 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIW81035.1 - 1.5e-12 48.0 0.0 0.0034 17.4 0.0 4.4 2 2 1 3 3 3 2 AAA domain ABC_ATPase PF09818.4 EIW81035.1 - 2.7e-10 39.4 0.2 0.00014 20.6 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EIW81035.1 - 4.1e-07 29.4 2.0 0.0024 17.3 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EIW81035.1 - 6.9e-07 29.4 2.9 0.0023 17.9 0.1 3.2 3 0 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EIW81035.1 - 1.3e-06 29.2 0.0 0.066 14.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EIW81035.1 - 1.3e-05 24.4 0.0 0.11 11.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 EIW81035.1 - 0.00011 21.9 0.3 4.7 6.7 0.0 4.2 4 0 0 4 4 4 0 AAA domain G-alpha PF00503.15 EIW81035.1 - 0.00014 20.7 0.0 0.33 9.5 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_18 PF13238.1 EIW81035.1 - 0.00021 21.6 0.0 1.1 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIW81035.1 - 0.0003 20.9 3.9 0.36 10.9 0.3 3.9 2 2 0 2 2 2 1 AAA domain AAA PF00004.24 EIW81035.1 - 0.001 19.2 1.2 1.9 8.7 0.1 4.1 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EIW81035.1 - 0.0011 18.4 1.0 1 8.7 0.0 3.4 4 0 0 4 4 4 1 AAA domain DUF87 PF01935.12 EIW81035.1 - 0.0015 18.3 0.3 1 9.1 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function DUF87 AAA_5 PF07728.9 EIW81035.1 - 0.0017 18.0 0.1 3 7.5 0.0 3.3 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EIW81035.1 - 0.0024 17.7 0.0 3.6 7.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EIW81035.1 - 0.0025 17.6 7.5 0.6 10.0 0.2 3.8 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.1 EIW81035.1 - 0.0054 16.6 0.0 3.2 7.6 0.0 3.6 4 0 0 4 4 3 1 AAA domain AAA_28 PF13521.1 EIW81035.1 - 0.0088 16.0 1.4 1.6 8.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain DUF1525 PF07511.6 EIW81035.1 - 0.0096 15.9 0.0 0.035 14.1 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1525) AAA_10 PF12846.2 EIW81035.1 - 0.0096 15.3 0.7 9.8 5.5 0.1 3.4 4 0 0 4 4 3 0 AAA-like domain Zeta_toxin PF06414.7 EIW81035.1 - 0.014 14.4 1.4 1.7 7.6 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin AAA_23 PF13476.1 EIW81035.1 - 0.017 15.4 2.8 1.3 9.3 0.0 2.7 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.8 EIW81035.1 - 0.019 13.8 0.0 5.9 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 EIW81035.1 - 0.032 13.3 0.0 6.7 5.8 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI MobB PF03205.9 EIW81035.1 - 0.035 13.7 0.6 11 5.7 0.0 3.0 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EIW81035.1 - 0.039 14.4 0.0 15 6.1 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein RNA_helicase PF00910.17 EIW81035.1 - 0.047 13.8 0.0 7.9 6.7 0.0 3.1 2 0 0 2 2 2 0 RNA helicase PRK PF00485.13 EIW81035.1 - 0.054 13.0 0.0 5.8 6.4 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family MMR_HSR1 PF01926.18 EIW81035.1 - 0.054 13.4 0.1 16 5.5 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.20 EIW81035.1 - 0.058 12.8 0.1 15 5.0 0.0 2.9 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain NB-ARC PF00931.17 EIW81035.1 - 0.061 12.1 0.1 2.5 6.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Synapsin_N PF10581.4 EIW81035.1 - 0.1 12.4 0.0 4.9 7.0 0.0 2.4 2 0 0 2 2 2 0 Synapsin N-terminal AAA_15 PF13175.1 EIW81035.1 - 0.32 10.0 0.0 6.4 5.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain Pkinase PF00069.20 EIW81036.1 - 2e-69 233.6 0.0 2.5e-69 233.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW81036.1 - 1.3e-31 109.6 0.0 1.8e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EIW81036.1 - 2e-08 34.6 4.1 2e-08 34.6 2.8 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EIW81036.1 - 3.2e-05 23.0 0.0 7.7e-05 21.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIW81036.1 - 0.0072 15.4 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW81036.1 - 0.043 13.5 0.0 0.074 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIW81036.1 - 0.14 11.7 0.1 0.23 11.0 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase BetaGal_dom4_5 PF13364.1 EIW81037.1 - 2.2e-23 82.6 2.5 3.8e-18 65.7 0.1 3.2 3 1 1 4 4 4 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EIW81037.1 - 5.3e-19 67.3 0.6 1.1e-18 66.3 0.1 1.8 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 BetaGal_dom2 PF10435.4 EIW81037.1 - 0.06 12.6 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase, domain 2 DEAD PF00270.24 EIW81038.1 - 4.5e-18 65.3 0.0 1.1e-17 64.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW81038.1 - 3.9e-08 33.0 0.0 9.2e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW81038.1 - 1.5e-06 28.1 0.0 2.2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIW81038.1 - 0.004 17.2 0.1 0.023 14.8 0.0 2.2 2 1 0 2 2 2 1 AAA domain FmdE PF02663.9 EIW81038.1 - 0.024 14.5 0.0 9.6 6.1 0.0 3.3 3 0 0 3 3 3 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon G-patch PF01585.18 EIW81040.1 - 1.3e-07 31.3 0.2 1.3e-06 28.1 0.2 2.2 2 0 0 2 2 2 1 G-patch domain F-box-like PF12937.2 EIW81041.1 - 5.4e-08 32.4 0.0 1.9e-07 30.6 0.0 2.1 1 0 0 1 1 1 1 F-box-like NTR2 PF15458.1 EIW81041.1 - 0.0045 16.2 1.2 0.0075 15.5 0.8 1.3 1 0 0 1 1 1 1 Nineteen complex-related protein 2 CM_2 PF01817.16 EIW81041.1 - 0.12 12.4 0.1 0.32 11.1 0.1 1.7 1 0 0 1 1 1 0 Chorismate mutase type II LRR_7 PF13504.1 EIW81041.1 - 1.2 9.6 10.5 29 5.4 0.1 6.0 6 1 0 6 6 6 0 Leucine rich repeat PQ-loop PF04193.9 EIW81042.1 - 3.3e-34 116.2 13.9 1.2e-19 69.6 2.5 2.9 3 0 0 3 3 3 2 PQ loop repeat Band_7 PF01145.20 EIW81043.1 - 2.5e-20 73.1 1.3 4e-20 72.4 0.9 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family TFIIA PF03153.8 EIW81044.1 - 9.6e-54 183.6 8.2 3.3e-34 119.4 0.4 2.0 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EIW81044.1 - 0.36 9.0 29.7 0.5 8.5 20.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LIN37 PF15306.1 EIW81044.1 - 2.9 7.8 11.6 0.09 12.7 2.9 2.1 2 1 0 2 2 2 0 LIN37 MutS_V PF00488.16 EIW81045.1 - 6.3e-51 173.0 0.0 1.3e-50 172.0 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EIW81045.1 - 2.2e-32 112.5 0.0 4.3e-32 111.5 0.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EIW81045.1 - 0.071 13.2 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 MutS family domain IV AAA_14 PF13173.1 EIW81045.1 - 0.09 12.6 0.0 3.4 7.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain Mito_carr PF00153.22 EIW81046.1 - 8e-44 147.2 3.6 2.1e-16 59.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein FA_desaturase PF00487.19 EIW81047.1 - 0.47 9.8 5.7 1.1 8.6 3.2 1.8 1 1 1 2 2 2 0 Fatty acid desaturase DUF1772 PF08592.6 EIW81048.1 - 0.00012 21.8 2.9 0.00015 21.4 2.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) CBP4 PF07960.6 EIW81048.1 - 0.017 14.7 0.1 0.34 10.5 0.0 2.0 1 1 1 2 2 2 0 CBP4 CopD PF05425.8 EIW81048.1 - 0.2 11.8 4.5 0.19 11.9 1.3 2.0 2 0 0 2 2 2 0 Copper resistance protein D Motile_Sperm PF00635.21 EIW81049.1 - 1.1e-25 89.4 0.2 2e-25 88.5 0.1 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Sod_Cu PF00080.15 EIW81050.1 - 2.9e-48 163.6 3.2 3.8e-48 163.2 2.2 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) ECR1_N PF14382.1 EIW81051.1 - 0.095 12.0 0.2 0.17 11.2 0.1 1.4 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region DUF221 PF02714.10 EIW81052.1 - 1.1e-50 172.3 20.1 2.4e-50 171.2 13.9 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EIW81052.1 - 4.5e-15 55.5 0.2 4.5e-15 55.5 0.1 2.3 2 0 0 2 2 2 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EIW81052.1 - 8.1e-05 23.0 1.6 0.0022 18.4 1.1 2.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_5 PF13893.1 EIW81052.1 - 0.041 13.7 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW81052.1 - 0.054 13.4 0.1 0.28 11.1 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) ETC_C1_NDUFA4 PF04800.7 EIW81053.1 - 7.2e-36 122.1 0.5 8.1e-36 121.9 0.3 1.0 1 0 0 1 1 1 1 ETC complex I subunit conserved region Pyr_redox_3 PF13738.1 EIW81054.1 - 7.4e-17 62.0 0.0 1.1e-16 61.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIW81054.1 - 1.3e-13 50.0 1.5 2.6e-12 45.7 0.2 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EIW81054.1 - 7.4e-10 38.7 0.0 2.2e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EIW81054.1 - 1e-06 27.9 0.1 8.8e-06 24.8 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EIW81054.1 - 8.7e-06 25.7 0.0 0.00022 21.1 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIW81054.1 - 0.00018 21.3 0.0 0.00056 19.7 0.0 1.8 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EIW81054.1 - 0.0083 15.0 0.0 0.013 14.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIW81054.1 - 0.051 12.4 0.1 0.12 11.2 0.1 1.7 1 1 0 1 1 1 0 FAD dependent oxidoreductase RICTOR_N PF14664.1 EIW81055.1 - 2.9e-89 299.2 1.1 2.1e-88 296.4 0.2 2.2 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EIW81055.1 - 4.6e-74 248.2 1.6 1.6e-72 243.1 0.2 3.6 4 1 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EIW81055.1 - 1.2e-33 115.4 0.2 1.7e-32 111.7 0.1 2.5 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EIW81055.1 - 1.5e-28 98.4 0.5 1.5e-26 92.1 0.0 3.8 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 EIW81055.1 - 0.013 15.2 2.3 0.029 14.0 1.6 1.6 1 0 0 1 1 1 0 Hr1 repeat Ribosomal_L22 PF00237.14 EIW81056.1 - 3.2e-30 104.1 0.0 7e-30 103.0 0.0 1.5 1 1 1 2 2 2 1 Ribosomal protein L22p/L17e RasGEF PF00617.14 EIW81057.1 - 5.3e-19 68.6 0.0 1.1e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EIW81057.1 - 5.2e-10 39.3 0.0 7.4e-09 35.6 0.0 2.5 2 0 0 2 2 2 1 RasGEF N-terminal motif Ribosomal_S30AE PF02482.14 EIW81057.1 - 0.066 13.6 0.5 0.17 12.3 0.4 1.7 1 0 0 1 1 1 0 Sigma 54 modulation protein / S30EA ribosomal protein HECT PF00632.20 EIW81058.1 - 2.1e-91 306.4 0.0 2.7e-91 306.0 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EIW81058.1 - 8.5e-34 115.0 16.1 3.6e-12 45.8 0.3 3.5 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EIW81058.1 - 3.9e-12 45.8 0.0 8.6e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain Acyl-CoA_dh_1 PF00441.19 EIW81059.1 - 5.4e-21 75.2 3.2 9.1e-21 74.5 2.2 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 EIW81059.1 - 4.9e-07 30.0 1.6 7.9e-07 29.3 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EIW81059.1 - 5e-06 25.9 0.3 1.1e-05 24.8 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EIW81059.1 - 0.004 17.7 0.0 0.012 16.1 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Thi4 PF01946.12 EIW81060.1 - 1.7e-92 308.7 0.0 2e-92 308.4 0.0 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EIW81060.1 - 1.1e-09 37.6 1.3 1.6e-09 37.1 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIW81060.1 - 4.6e-07 29.0 0.2 1.9e-06 27.0 0.1 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EIW81060.1 - 1.2e-06 28.4 0.0 2.9e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EIW81060.1 - 2e-06 27.6 0.3 7.7e-05 22.5 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EIW81060.1 - 1e-05 25.5 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW81060.1 - 0.00012 21.0 0.9 0.00058 18.8 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EIW81060.1 - 0.00049 20.2 0.1 0.00098 19.2 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW81060.1 - 0.0019 16.7 0.2 0.0028 16.2 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 EIW81060.1 - 0.0029 16.7 0.1 0.0046 16.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EIW81060.1 - 0.049 12.4 0.0 0.17 10.7 0.0 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EIW81060.1 - 0.069 11.7 0.1 0.096 11.2 0.1 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Amino_oxidase PF01593.19 EIW81060.1 - 0.14 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase CM_2 PF01817.16 EIW81061.1 - 1.1e-09 38.2 0.2 2.1e-07 30.9 0.0 2.8 2 1 0 2 2 2 2 Chorismate mutase type II Septin PF00735.13 EIW81062.1 - 6.9e-45 153.2 0.0 4.2e-17 62.0 0.0 4.0 4 0 0 4 4 4 3 Septin MMR_HSR1 PF01926.18 EIW81062.1 - 0.00039 20.3 0.0 0.00077 19.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIW81062.1 - 0.00068 20.1 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EIW81062.1 - 0.00092 19.0 0.1 0.97 9.2 0.0 2.4 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 EIW81062.1 - 0.0021 17.5 0.0 0.0045 16.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EIW81062.1 - 0.0045 17.1 0.0 0.014 15.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIW81062.1 - 0.0053 16.7 0.0 0.016 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EIW81062.1 - 0.0062 16.0 0.0 0.015 14.7 0.0 1.6 1 0 0 1 1 1 1 FtsK/SpoIIIE family DUF815 PF05673.8 EIW81062.1 - 0.015 14.2 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.1 EIW81062.1 - 0.04 13.7 0.1 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_32 PF13654.1 EIW81062.1 - 0.063 11.9 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.7 EIW81062.1 - 0.093 12.0 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein Septin PF00735.13 EIW81063.1 - 1.5e-32 112.7 0.0 4.1e-10 39.1 0.0 3.1 3 0 0 3 3 3 3 Septin Zn_clus PF00172.13 EIW81063.1 - 5.5e-21 74.1 28.3 9.7e-11 41.3 6.2 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Septin PF00735.13 EIW81064.1 - 1.5e-16 60.3 0.0 9.1e-09 34.7 0.0 2.1 2 0 0 2 2 2 2 Septin Zn_clus PF00172.13 EIW81065.1 - 1.6e-10 40.6 10.3 2.7e-10 39.9 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ILVD_EDD PF00920.16 EIW81066.1 - 3.3e-202 672.5 0.8 3.9e-202 672.3 0.5 1.0 1 0 0 1 1 1 1 Dehydratase family RIO1 PF01163.17 EIW81067.1 - 9.6e-72 240.3 0.0 9.6e-72 240.3 0.0 1.6 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EIW81067.1 - 7.6e-05 22.5 0.9 0.32 10.7 0.1 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EIW81067.1 - 0.00094 18.2 0.5 0.01 14.9 0.4 2.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EIW81067.1 - 0.034 13.2 0.0 0.07 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein kinase domain DUF4504 PF14953.1 EIW81069.1 - 2.7e-06 26.8 0.1 3.2e-06 26.6 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4504) Pro_isomerase PF00160.16 EIW81070.1 - 1.1e-45 155.5 0.0 1.9e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EIW81070.1 - 2.6e-10 39.7 2.4 0.0013 18.5 0.0 4.4 5 0 0 5 5 5 3 WD domain, G-beta repeat zf-AN1 PF01428.11 EIW81071.1 - 4.2e-21 74.5 26.8 7.5e-12 44.9 4.3 2.7 2 1 1 3 3 3 2 AN1-like Zinc finger Transp_Tc5_C PF04236.10 EIW81071.1 - 0.061 13.5 18.9 0.27 11.4 3.9 2.5 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain His_Phos_1 PF00300.17 EIW81072.1 - 1.2e-27 96.8 0.0 1.8e-27 96.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Ribosomal_L35p PF01632.14 EIW81073.1 - 6.4e-13 48.3 1.4 7.9e-13 48.1 1.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L35 Ufd2P_core PF10408.4 EIW81074.1 - 5.9e-187 622.7 0.0 7e-187 622.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EIW81074.1 - 1.1e-28 98.9 1.2 1.3e-27 95.5 0.4 2.8 2 0 0 2 2 2 1 U-box domain RE_MjaI PF09568.5 EIW81074.1 - 0.056 12.9 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 MjaI restriction endonuclease Eaf7 PF07904.8 EIW81075.1 - 1.6e-14 53.6 0.0 2.3e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 ENTH PF01417.15 EIW81077.1 - 1.9e-43 147.2 0.1 2.7e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EIW81077.1 - 0.0024 16.6 0.0 0.0041 15.8 0.0 1.4 1 0 0 1 1 1 1 ANTH domain GRP PF07172.6 EIW81077.1 - 0.022 15.1 31.8 0.12 12.8 5.6 3.4 3 0 0 3 3 3 0 Glycine rich protein family NOT2_3_5 PF04153.13 EIW81078.1 - 6.8e-33 113.4 0.4 6.8e-33 113.4 0.3 2.7 4 0 0 4 4 4 1 NOT2 / NOT3 / NOT5 family RNA_pol_Rpb4 PF03874.11 EIW81079.1 - 1.2e-21 76.9 0.2 1.5e-21 76.5 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 Prenyltrans PF00432.16 EIW81080.1 - 4.1e-28 96.6 10.9 2.9e-09 36.3 0.2 5.3 5 0 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EIW81080.1 - 6.2e-23 81.3 0.1 1.2e-11 45.0 0.0 3.4 2 2 1 3 3 3 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EIW81080.1 - 1.3e-06 28.3 0.0 0.043 13.8 0.0 2.8 1 1 2 3 3 3 3 Prenyltransferase-like PAM2 PF07145.10 EIW81081.1 - 0.0026 17.1 0.1 0.0058 16.0 0.1 1.5 1 0 0 1 1 1 1 Ataxin-2 C-terminal region HET PF06985.6 EIW81082.1 - 2e-05 24.8 1.9 3e-05 24.2 0.5 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TGF_beta_GS PF08515.7 EIW81083.1 - 0.28 10.5 1.9 0.64 9.3 1.3 1.7 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Abhydrolase_5 PF12695.2 EIW81084.1 - 6.6e-05 22.7 0.0 0.0001 22.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EIW81084.1 - 0.00025 20.7 0.0 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EIW81084.1 - 0.00033 20.5 0.6 0.00065 19.6 0.4 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EIW81084.1 - 0.031 13.5 0.0 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) ELFV_dehydrog PF00208.16 EIW81085.1 - 1.5e-50 172.0 0.0 2.3e-50 171.4 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EIW81085.1 - 2.2e-18 65.2 0.0 3.8e-13 47.8 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EIW81085.1 - 0.026 14.1 0.0 0.072 12.6 0.0 1.7 1 1 0 1 1 1 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Pkinase PF00069.20 EIW81087.1 - 4.1e-06 26.1 0.0 8.8e-06 25.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW81087.1 - 0.0024 17.0 0.0 0.0053 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW81087.1 - 0.018 14.8 0.0 0.046 13.4 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 EIW81088.1 - 1.5e-06 27.5 0.0 2.8e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW81088.1 - 0.00077 18.6 0.0 0.0014 17.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW81088.1 - 0.0049 16.6 0.1 0.02 14.6 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family adh_short PF00106.20 EIW81089.1 - 2e-27 96.1 0.4 2.9e-27 95.6 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW81089.1 - 1.6e-12 47.7 0.0 2.1e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW81089.1 - 2.1e-09 37.3 0.1 3.7e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EIW81089.1 - 0.013 15.2 0.4 0.024 14.2 0.3 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF1490 PF07371.7 EIW81089.1 - 0.018 14.9 1.0 0.042 13.7 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1490) SAM_2 PF07647.12 EIW81090.1 - 8.9e-08 31.8 0.0 5.1e-07 29.4 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EIW81090.1 - 2.8e-06 27.4 0.0 1.5e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) ALIX_LYPXL_bnd PF13949.1 EIW81090.1 - 0.013 14.4 0.3 0.026 13.5 0.2 1.4 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV DUF4508 PF14969.1 EIW81090.1 - 0.18 11.8 0.6 0.32 11.0 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4508) DIOX_N PF14226.1 EIW81091.1 - 1.3e-31 109.5 0.0 1.7e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIW81092.1 - 1.1e-19 70.5 0.0 1.3e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.20 EIW81093.1 - 8.2e-14 51.8 3.6 6e-13 49.0 0.1 2.5 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW81093.1 - 6.5e-11 42.4 0.0 0.00032 20.5 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW81093.1 - 4e-05 23.3 0.1 8.8e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 KR domain Pyr_redox PF00070.22 EIW81093.1 - 0.035 14.5 0.3 0.063 13.6 0.2 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Epimerase PF01370.16 EIW81093.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Dynamin_N PF00350.18 EIW81095.1 - 6.2e-17 61.9 0.4 2.8e-16 59.8 0.1 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EIW81095.1 - 3.5e-12 46.3 0.4 1.5e-10 40.9 0.0 3.3 2 2 1 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIW81095.1 - 3.4e-08 33.1 0.2 2.1e-07 30.5 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EIW81095.1 - 6.8e-05 23.3 0.1 0.015 15.7 0.0 2.9 2 1 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 EIW81095.1 - 0.0022 17.4 0.2 0.007 15.8 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 EIW81095.1 - 0.013 14.9 0.0 1.4 8.3 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EIW81095.1 - 0.054 13.6 0.0 9.4 6.3 0.0 3.7 4 0 0 4 4 4 0 AAA domain FtsK_SpoIIIE PF01580.13 EIW81095.1 - 0.057 12.8 0.0 0.23 10.9 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family ADH_zinc_N PF00107.21 EIW81096.1 - 5.4e-28 97.1 0.0 8.6e-28 96.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW81096.1 - 1.6e-14 54.8 0.0 3.7e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW81096.1 - 9.3e-13 47.8 0.1 2e-12 46.8 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Abhydrolase_6 PF12697.2 EIW81097.1 - 4.4e-13 49.6 1.8 5.8e-13 49.2 1.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW81097.1 - 2.7e-09 36.9 0.1 3.7e-09 36.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIW81097.1 - 5.2e-08 32.3 0.2 8.8e-08 31.6 0.2 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EIW81097.1 - 9.1e-05 22.1 0.4 0.0084 15.6 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF1749 PF08538.5 EIW81097.1 - 0.00021 20.3 0.0 0.00031 19.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF915 PF06028.6 EIW81097.1 - 0.023 13.7 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Ribosomal_L1 PF00687.16 EIW81098.1 - 1.2e-58 198.0 2.4 1.9e-58 197.4 1.7 1.3 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family F-box-like PF12937.2 EIW81099.1 - 0.064 12.9 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 F-box-like MFS_1 PF07690.11 EIW81101.1 - 1e-21 77.0 27.1 1.4e-21 76.6 18.8 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EIW81101.1 - 0.0016 16.9 16.1 0.0018 16.7 10.2 1.7 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 EIW81101.1 - 0.0081 15.9 0.1 0.0081 15.9 0.0 2.2 2 0 0 2 2 2 1 MFS_1 like family Acetyltransf_1 PF00583.19 EIW81103.1 - 1.6e-10 40.8 0.0 9.8e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIW81103.1 - 0.00011 22.2 0.0 0.00025 21.1 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIW81103.1 - 0.091 12.9 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EIW81103.1 - 0.14 11.9 0.1 0.47 10.2 0.0 1.9 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase Pectinesterase PF01095.14 EIW81104.1 - 8.8e-36 122.9 1.0 3.6e-31 107.8 0.8 2.1 2 0 0 2 2 2 2 Pectinesterase Syntaxin_2 PF14523.1 EIW81105.1 - 6.1e-21 74.3 7.9 1.4e-20 73.1 2.0 2.4 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EIW81105.1 - 1e-19 69.9 1.2 2.6e-19 68.6 0.8 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.20 EIW81105.1 - 0.00028 20.9 5.9 0.0071 16.4 0.6 2.4 2 0 0 2 2 2 2 Syntaxin MCPsignal PF00015.16 EIW81105.1 - 0.0016 18.0 0.9 0.0016 18.0 0.6 2.2 1 1 1 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Synaptobrevin PF00957.16 EIW81105.1 - 0.056 13.0 0.1 0.056 13.0 0.1 2.3 2 1 0 2 2 2 0 Synaptobrevin DUF912 PF06024.7 EIW81105.1 - 0.61 10.1 2.4 1.8 8.6 0.1 2.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) V-SNARE PF05008.10 EIW81105.1 - 0.85 9.8 5.7 1.2 9.2 0.3 3.1 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus Fib_alpha PF08702.5 EIW81105.1 - 3.8 7.6 9.8 6 6.9 0.3 3.1 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family Pkinase PF00069.20 EIW81107.1 - 4.2e-69 232.5 0.0 8.9e-69 231.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW81107.1 - 1e-49 168.9 0.0 1.7e-49 168.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW81107.1 - 0.00026 20.0 0.0 0.00083 18.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Ribosomal_L5_C PF00673.16 EIW81108.1 - 2e-12 46.6 0.0 5e-12 45.3 0.0 1.7 1 1 0 1 1 1 1 ribosomal L5P family C-terminus Peptidase_M64 PF09471.5 EIW81109.1 - 9.6e-29 100.8 0.0 1.5e-28 100.2 0.0 1.2 1 0 0 1 1 1 1 IgA Peptidase M64 GH114_assoc PF14741.1 EIW81110.1 - 0.091 12.4 0.2 0.13 11.9 0.1 1.4 1 1 0 1 1 1 0 N-terminal glycosyl-hydrolase-114-associated domain Mito_carr PF00153.22 EIW81111.1 - 9.1e-54 179.1 7.4 3.3e-19 68.3 0.2 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein TAF PF02969.12 EIW81112.1 - 1.4e-24 85.8 0.3 2.5e-24 84.9 0.2 1.4 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) DUF1546 PF07571.8 EIW81112.1 - 5.7e-15 55.1 0.2 2.7e-14 53.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1546) Histone PF00125.19 EIW81112.1 - 4.4e-07 29.9 0.3 1.2e-06 28.5 0.2 1.8 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EIW81112.1 - 0.00085 19.0 0.0 0.0022 17.7 0.0 1.7 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.18 EIW81112.1 - 0.04 13.9 0.3 0.12 12.4 0.1 1.8 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 EIW81112.1 - 0.047 13.8 0.2 0.099 12.8 0.1 1.5 1 0 0 1 1 1 0 Kinetochore component CENP-S HEAT_PBS PF03130.11 EIW81112.1 - 0.16 12.5 3.3 21 5.9 0.1 4.0 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EIW81112.1 - 1.9 9.0 11.0 2.4 8.7 0.0 4.4 3 2 1 4 4 4 0 HEAT-like repeat MgtE_N PF03448.12 EIW81113.1 - 0.005 17.1 1.3 0.84 9.9 0.0 2.8 2 0 0 2 2 2 2 MgtE intracellular N domain DUF4404 PF14357.1 EIW81113.1 - 0.96 9.9 3.8 1.3 9.5 0.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Pectinesterase PF01095.14 EIW81114.1 - 1.6e-39 135.2 5.3 3.1e-38 131.0 3.7 2.0 1 1 0 1 1 1 1 Pectinesterase Pectate_lyase_3 PF12708.2 EIW81114.1 - 0.0017 18.5 6.0 0.0031 17.6 4.2 1.4 1 0 0 1 1 1 1 Pectate lyase superfamily protein Pentapeptide_3 PF13576.1 EIW81114.1 - 5.8 6.8 11.1 44 4.0 4.9 3.2 2 1 0 2 2 2 0 Pentapeptide repeats (9 copies) Zn_clus PF00172.13 EIW81116.1 - 0.0055 16.5 11.0 0.0091 15.8 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GFA PF04828.9 EIW81117.1 - 5.3e-23 80.7 0.7 7.6e-23 80.2 0.5 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Cys_rich_CWC PF14375.1 EIW81117.1 - 0.035 14.0 3.4 0.035 14.0 2.3 1.9 2 0 0 2 2 2 0 Cysteine-rich CWC RNA_POL_M_15KD PF02150.11 EIW81117.1 - 0.17 11.6 2.5 0.2 11.3 0.0 2.2 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit GFA PF04828.9 EIW81118.1 - 1.5e-24 85.7 0.8 2.1e-24 85.2 0.6 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Cys_rich_CWC PF14375.1 EIW81118.1 - 0.035 14.0 1.7 0.035 14.0 1.2 1.8 2 0 0 2 2 2 0 Cysteine-rich CWC RNA_POL_M_15KD PF02150.11 EIW81118.1 - 0.051 13.2 1.3 0.34 10.6 0.0 2.4 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit CoA_transf_3 PF02515.12 EIW81119.1 - 6.2e-42 142.9 0.0 6.2e-38 129.9 0.0 2.3 2 0 0 2 2 2 2 CoA-transferase family III Peptidase_M16 PF00675.15 EIW81120.1 - 1.1e-54 184.1 0.4 1.9e-54 183.4 0.1 1.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EIW81120.1 - 7.5e-42 143.0 0.0 1.2e-40 139.1 0.0 2.4 3 0 0 3 3 3 1 Peptidase M16 inactive domain WD40 PF00400.27 EIW81121.1 - 3.9e-16 58.2 17.7 1.8e-09 37.1 0.6 8.0 9 1 0 9 9 9 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW81121.1 - 1.1e-06 28.2 0.1 0.0002 20.9 0.0 3.5 3 1 0 3 3 3 1 PQQ-like domain PD40 PF07676.7 EIW81121.1 - 2.8e-06 26.8 4.8 6.8 6.4 0.0 7.7 9 0 0 9 9 9 2 WD40-like Beta Propeller Repeat PQQ PF01011.16 EIW81121.1 - 0.00077 18.8 0.2 22 4.8 0.0 4.7 4 0 0 4 4 4 0 PQQ enzyme repeat eIF2A PF08662.6 EIW81121.1 - 0.023 14.4 0.0 3.9 7.1 0.0 4.0 4 1 1 5 5 5 0 Eukaryotic translation initiation factor eIF2A Gmad1 PF10647.4 EIW81121.1 - 0.023 14.0 0.2 0.29 10.5 0.0 2.8 4 0 0 4 4 4 0 Lipoprotein LpqB beta-propeller domain Proteasome_A_N PF10584.4 EIW81121.1 - 0.23 10.8 12.5 4.4 6.7 0.0 6.0 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature DUF1576 PF07613.6 EIW81122.1 - 0.12 11.8 0.1 0.45 9.9 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1576) zf-RING_2 PF13639.1 EIW81124.1 - 3.9e-14 52.2 4.2 6.1e-14 51.5 2.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIW81124.1 - 8.2e-09 35.4 3.4 1.6e-08 34.5 2.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EIW81124.1 - 5.6e-08 32.3 1.9 8.9e-08 31.6 1.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW81124.1 - 1.1e-07 31.6 2.6 1.8e-07 31.0 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW81124.1 - 1.4e-07 31.1 2.2 2.1e-07 30.5 1.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIW81124.1 - 1.3e-06 27.9 2.1 2.1e-06 27.2 1.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIW81124.1 - 0.00022 21.0 1.7 0.00043 20.0 1.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EIW81124.1 - 0.011 15.8 3.4 0.018 15.1 2.4 1.4 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 EIW81124.1 - 0.022 14.3 4.9 0.038 13.5 3.4 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EIW81124.1 - 0.053 13.5 1.7 0.098 12.6 1.2 1.4 1 0 0 1 1 1 0 RING-like domain PHD PF00628.24 EIW81124.1 - 0.9 9.2 4.0 1.4 8.6 2.8 1.3 1 0 0 1 1 1 0 PHD-finger SCIMP PF15050.1 EIW81124.1 - 6.7 6.6 6.1 28 4.6 4.2 2.2 1 0 0 1 1 1 0 SCIMP protein ETF PF01012.16 EIW81125.1 - 3.3e-36 124.4 0.8 4.3e-36 124.0 0.6 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ADH_N PF08240.7 EIW81126.1 - 8.4e-30 102.7 0.1 1.5e-29 101.9 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW81126.1 - 2.4e-23 82.1 0.1 4.4e-23 81.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW81126.1 - 1.2e-06 29.4 0.1 2.3e-06 28.4 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EIW81126.1 - 0.033 13.5 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pex24p PF06398.6 EIW81127.1 - 6.1e-25 87.7 4.4 1.1e-15 57.3 0.0 2.1 2 0 0 2 2 2 2 Integral peroxisomal membrane peroxin YwiC PF14256.1 EIW81127.1 - 1.9 8.5 7.8 0.37 10.8 1.8 2.0 1 1 1 2 2 2 0 YwiC-like protein WD40 PF00400.27 EIW81132.1 - 2e-93 303.2 40.7 3.2e-09 36.3 0.0 14.9 15 0 0 15 15 15 13 WD domain, G-beta repeat PD40 PF07676.7 EIW81132.1 - 3.4e-09 36.1 3.1 2.2 8.0 0.0 7.8 8 0 0 8 8 8 3 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EIW81132.1 - 3.4e-09 36.2 5.2 6.7 5.7 0.0 8.4 5 1 3 9 9 9 4 Neuroblastoma-amplified sequence, N terminal Hira PF07569.6 EIW81132.1 - 4.2e-05 22.8 0.0 0.31 10.2 0.0 5.1 6 1 1 7 7 7 1 TUP1-like enhancer of split Cytochrom_D1 PF02239.11 EIW81132.1 - 0.00027 19.3 0.1 4.4 5.5 0.0 4.4 4 1 0 5 5 5 2 Cytochrome D1 heme domain Lactonase PF10282.4 EIW81132.1 - 0.00054 19.1 0.0 0.96 8.4 0.0 4.5 5 2 0 5 5 5 1 Lactonase, 7-bladed beta-propeller Clathrin_propel PF01394.15 EIW81132.1 - 0.057 13.7 0.7 2.2 8.7 0.1 3.7 3 0 0 3 3 3 0 Clathrin propeller repeat PQQ_3 PF13570.1 EIW81132.1 - 1.3 9.4 20.7 1.2 9.5 0.4 7.1 8 1 0 8 8 8 0 PQQ-like domain DUF2305 PF10230.4 EIW81134.1 - 5.3e-47 160.4 0.0 3.7e-46 157.6 0.0 2.0 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EIW81134.1 - 3.4e-09 36.9 6.3 1.3e-08 34.9 4.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW81134.1 - 4.3e-09 36.2 0.1 1.9e-08 34.1 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EIW81134.1 - 0.00013 21.5 0.1 0.00033 20.3 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EIW81134.1 - 0.0025 17.4 0.0 0.0062 16.1 0.0 1.5 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_2 PF02230.11 EIW81134.1 - 0.051 13.0 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase XPG_N PF00752.12 EIW81137.1 - 2.5e-30 104.7 0.0 1.2e-27 96.0 0.0 2.4 2 0 0 2 2 2 2 XPG N-terminal domain XPG_I PF00867.13 EIW81137.1 - 4.2e-29 100.4 0.0 8.1e-29 99.5 0.0 1.5 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EIW81137.1 - 4e-07 30.2 0.1 9.8e-07 28.9 0.1 1.6 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold Hist_deacetyl PF00850.14 EIW81142.1 - 5.7e-60 203.2 0.2 7.3e-60 202.8 0.2 1.2 1 0 0 1 1 1 1 Histone deacetylase domain RPA_C PF08784.6 EIW81143.1 - 2.5e-13 50.2 0.1 5.9e-13 49.1 0.1 1.6 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EIW81143.1 - 6.4e-05 22.7 0.1 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Uteroglobin PF01099.12 EIW81146.1 - 0.11 12.3 0.1 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Uteroglobin family Glyco_hydro_35 PF01301.14 EIW81147.1 - 3.4e-65 220.4 0.6 5.1e-65 219.9 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 EIW81147.1 - 3.9e-43 146.2 17.0 2.2e-22 79.4 0.8 4.1 4 0 0 4 4 4 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 EIW81147.1 - 1.2e-38 132.2 5.9 1.2e-38 132.2 4.1 1.7 2 0 0 2 2 2 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 EIW81147.1 - 1.4e-22 78.8 1.1 5.6e-22 76.9 0.1 2.6 3 0 0 3 3 3 1 Beta-galactosidase, domain 3 DUF2301 PF10063.4 EIW81148.1 - 0.13 12.4 5.7 0.056 13.6 1.4 2.1 2 0 0 2 2 2 0 Uncharacterized integral membrane protein (DUF2301) Nop PF01798.13 EIW81149.1 - 4.4e-59 198.0 0.0 1e-58 196.9 0.0 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EIW81149.1 - 7.5e-25 86.4 0.0 1.7e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EIW81149.1 - 5.3e-23 80.9 0.3 5.3e-23 80.9 0.2 2.9 2 1 1 3 3 3 1 NOP5NT (NUC127) domain F-box PF00646.28 EIW81150.1 - 2.2e-05 24.0 0.0 5e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW81150.1 - 0.0035 17.0 0.2 0.0074 15.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like SSI PF00720.12 EIW81151.1 - 0.17 11.8 1.5 0.23 11.3 0.7 1.5 1 1 0 1 1 1 0 Subtilisin inhibitor-like CRAL_TRIO_2 PF13716.1 EIW81153.1 - 2.2e-33 115.2 0.2 3.5e-33 114.6 0.1 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain RhoGAP PF00620.22 EIW81153.1 - 3.4e-29 101.4 0.0 5.2e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain CRAL_TRIO PF00650.15 EIW81153.1 - 6.3e-06 25.7 0.1 4.7e-05 22.9 0.1 2.0 1 1 0 1 1 1 1 CRAL/TRIO domain Glyco_hydro_88 PF07470.8 EIW81155.1 - 1.2e-17 63.9 0.9 2e-17 63.2 0.6 1.3 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF4131 PF13567.1 EIW81156.1 - 0.099 12.0 1.0 0.15 11.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Oxidored_molyb PF00174.14 EIW81157.1 - 1.3e-46 158.1 0.0 5.3e-46 156.1 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EIW81157.1 - 4.6e-22 78.0 1.0 7.2e-22 77.4 0.7 1.3 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain tRNA_int_end_N2 PF12928.2 EIW81158.1 - 3.7e-19 67.9 0.0 9.3e-19 66.6 0.0 1.7 2 0 0 2 2 2 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EIW81158.1 - 0.042 13.3 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain RRM_1 PF00076.17 EIW81159.1 - 4.5e-11 42.2 0.3 0.00098 18.7 0.0 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW81159.1 - 5.8e-11 42.2 0.1 9.4e-09 35.1 0.0 3.3 3 1 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW81159.1 - 8.1e-06 25.5 0.2 0.12 12.2 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2 PF00096.21 EIW81160.1 - 7.9e-06 25.9 20.3 0.03 14.6 1.0 4.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW81160.1 - 0.00022 21.3 19.6 0.087 13.1 0.6 4.0 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIW81160.1 - 0.088 12.9 7.6 0.36 11.0 0.1 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIW81160.1 - 0.49 10.6 6.8 2.8 8.2 0.9 2.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type adh_short PF00106.20 EIW81161.1 - 5.7e-25 88.1 1.8 7.3e-25 87.8 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW81161.1 - 5.7e-16 59.0 0.0 7.5e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW81161.1 - 2.2e-08 33.9 1.0 5e-08 32.8 0.7 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW81161.1 - 0.00052 19.5 0.0 0.0018 17.7 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EIW81161.1 - 0.0018 17.3 0.2 0.0025 16.8 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EIW81161.1 - 0.008 16.2 0.4 0.019 14.9 0.3 1.6 1 0 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EIW81161.1 - 0.14 12.0 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Na_H_Exchanger PF00999.16 EIW81162.1 - 1.7e-55 188.0 24.4 2.1e-55 187.8 16.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NAD_binding_8 PF13450.1 EIW81163.1 - 6.8e-14 51.6 0.0 2.2e-13 49.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EIW81163.1 - 2.1e-11 43.5 0.0 5.7e-09 35.5 0.0 2.9 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 EIW81163.1 - 2.2e-05 23.5 0.0 0.0011 17.9 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EIW81163.1 - 3.6e-05 23.5 0.0 0.045 13.5 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EIW81163.1 - 4.8e-05 23.5 0.0 0.0012 18.9 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW81163.1 - 0.0039 16.0 0.0 0.0056 15.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIW81163.1 - 0.012 15.4 0.0 0.21 11.4 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW81163.1 - 0.083 11.9 0.0 0.19 10.8 0.0 1.5 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 EIW81164.1 - 2.3e-16 59.7 1.5 2.1e-07 30.3 0.1 2.5 2 1 0 2 2 2 2 FAD binding domain SE PF08491.5 EIW81164.1 - 0.1 11.3 0.0 0.38 9.5 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase Tenui_NCP PF04876.7 EIW81164.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Tenuivirus major non-capsid protein FAD_binding_3 PF01494.14 EIW81165.1 - 1.1e-05 24.7 0.2 1.6e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DUF258 PF03193.11 EIW81165.1 - 0.092 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 F-box-like PF12937.2 EIW81166.1 - 2.2e-07 30.5 2.8 7.1e-07 28.8 1.9 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIW81166.1 - 0.21 11.3 2.3 5.1 6.8 0.0 2.8 2 0 0 2 2 2 0 F-box domain MFS_1 PF07690.11 EIW81167.1 - 6.6e-30 103.9 38.0 2e-21 76.0 7.6 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW81167.1 - 5.1e-26 91.2 17.5 2.8e-22 78.9 2.4 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter GH3 PF03321.8 EIW81168.1 - 1.1e-61 208.9 0.0 1.5e-61 208.5 0.0 1.0 1 0 0 1 1 1 1 GH3 auxin-responsive promoter DUF462 PF04315.7 EIW81168.1 - 0.094 12.0 0.0 0.36 10.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF462 GH3 PF03321.8 EIW81169.1 - 1.8e-59 201.7 0.0 2.2e-59 201.3 0.0 1.0 1 0 0 1 1 1 1 GH3 auxin-responsive promoter IBN_N PF03810.14 EIW81171.1 - 5.9e-13 48.5 0.0 3.5e-11 42.8 0.0 3.3 2 2 1 3 3 3 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EIW81171.1 - 1.8e-06 28.0 5.0 0.074 13.3 0.1 3.8 3 0 0 3 3 3 3 HEAT repeats RIX1 PF08167.7 EIW81171.1 - 4.7e-05 23.1 0.3 0.0077 15.9 0.0 2.9 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Cnd1 PF12717.2 EIW81171.1 - 0.00047 20.0 0.1 0.0023 17.8 0.1 2.2 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Xpo1 PF08389.7 EIW81171.1 - 0.0018 18.1 0.1 0.015 15.1 0.0 2.7 3 0 0 3 3 3 1 Exportin 1-like protein Cse1 PF08506.5 EIW81171.1 - 0.0037 15.8 0.0 0.011 14.3 0.0 1.7 2 0 0 2 2 2 1 Cse1 HEAT PF02985.17 EIW81171.1 - 0.0062 16.5 3.5 0.94 9.7 0.0 4.5 4 0 0 4 4 4 1 HEAT repeat DUF2435 PF10363.4 EIW81171.1 - 0.026 14.3 0.6 0.12 12.2 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) DUF2407 PF10302.4 EIW81172.1 - 4.3e-14 52.4 0.0 6.9e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain DUF2407_C PF13373.1 EIW81172.1 - 9.1e-14 51.5 1.8 2.1e-11 43.9 2.3 3.4 2 1 0 2 2 2 1 DUF2407 C-terminal domain ubiquitin PF00240.18 EIW81172.1 - 0.00087 18.6 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Kin17_mid PF10357.4 EIW81173.1 - 6.8e-46 155.0 0.1 1.2e-45 154.2 0.1 1.4 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 EIW81173.1 - 0.00035 20.6 6.1 0.00072 19.6 4.3 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIW81173.1 - 0.0074 16.3 5.2 0.017 15.2 3.6 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EIW81173.1 - 0.031 14.3 2.3 0.031 14.3 1.6 1.7 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) Sen15 PF09631.5 EIW81175.1 - 3e-15 56.2 0.0 3.5e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Sen15 protein F-box-like PF12937.2 EIW81176.1 - 0.029 14.0 1.8 0.043 13.5 0.0 2.1 2 0 0 2 2 2 0 F-box-like LRR_4 PF12799.2 EIW81177.1 - 0.00045 19.7 0.3 0.013 15.0 0.0 3.5 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EIW81177.1 - 0.0013 18.3 0.1 0.025 14.2 0.0 2.7 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 EIW81177.1 - 0.097 12.4 0.5 1.2 8.9 0.1 3.0 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 EIW81178.1 - 0.0029 17.1 4.9 1.8 8.2 0.1 4.6 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) PUL PF08324.6 EIW81178.1 - 0.16 10.7 0.0 0.3 9.8 0.0 1.4 1 0 0 1 1 1 0 PUL domain Peptidase_M19 PF01244.16 EIW81180.1 - 1.2e-95 320.1 0.0 1.4e-95 319.9 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) DOPA_dioxygen PF08883.6 EIW81181.1 - 8.3e-29 99.7 0.0 9.7e-29 99.5 0.0 1.1 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family DAO PF01266.19 EIW81182.1 - 6.9e-51 173.2 0.5 1.2e-50 172.4 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW81182.1 - 1.2e-08 34.2 0.8 0.00043 19.2 0.3 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EIW81182.1 - 2.5e-07 30.1 0.7 1.6e-06 27.4 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIW81182.1 - 0.00083 19.2 0.2 0.0036 17.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIW81182.1 - 0.0015 17.6 0.4 0.014 14.4 0.3 2.1 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EIW81182.1 - 0.0027 16.8 3.0 0.0054 15.8 0.0 2.5 3 0 0 3 3 3 1 Thi4 family Lycopene_cycl PF05834.7 EIW81182.1 - 0.003 16.5 0.3 0.26 10.1 0.3 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EIW81182.1 - 0.003 17.5 0.4 0.011 15.7 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EIW81182.1 - 0.0045 15.8 0.4 0.13 11.1 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 EIW81182.1 - 0.012 15.2 0.1 0.025 14.2 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EIW81182.1 - 0.032 14.6 1.2 0.058 13.7 0.2 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW81182.1 - 0.034 12.6 0.6 0.053 11.9 0.4 1.2 1 0 0 1 1 1 0 HI0933-like protein Zn_clus PF00172.13 EIW81183.1 - 0.0044 16.9 11.1 0.049 13.5 2.6 2.3 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2360 PF10152.4 EIW81183.1 - 8.4 6.6 6.6 0.81 9.9 0.2 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Asp PF00026.18 EIW81184.1 - 1.8e-12 47.1 1.3 1.4e-05 24.5 0.0 3.2 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TMEM154 PF15102.1 EIW81184.1 - 8.4e-05 22.3 0.0 0.00018 21.2 0.0 1.5 1 0 0 1 1 1 1 TMEM154 protein family Herpes_gE PF02480.11 EIW81184.1 - 0.00084 17.7 0.0 0.0016 16.8 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Asp_protease_2 PF13650.1 EIW81184.1 - 0.0012 19.3 1.3 0.0042 17.5 0.0 2.5 3 0 0 3 3 3 1 Aspartyl protease Shisa PF13908.1 EIW81184.1 - 0.0024 18.0 0.0 0.0044 17.2 0.0 1.4 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator CD34_antigen PF06365.7 EIW81184.1 - 0.0055 16.3 0.0 0.0095 15.6 0.0 1.3 1 0 0 1 1 1 1 CD34/Podocalyxin family gag-asp_proteas PF13975.1 EIW81184.1 - 0.008 15.9 0.0 0.021 14.6 0.0 1.6 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease TMEM52 PF14979.1 EIW81184.1 - 0.013 15.3 0.5 0.026 14.4 0.4 1.4 1 0 0 1 1 1 0 Transmembrane 52 TAXi_N PF14543.1 EIW81184.1 - 0.022 14.7 0.6 0.26 11.2 0.1 2.7 2 1 0 2 2 2 0 Xylanase inhibitor N-terminal stn_TNFRSF12A PF12191.3 EIW81184.1 - 0.024 14.6 0.1 0.052 13.5 0.1 1.5 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain DUF3661 PF12400.3 EIW81184.1 - 0.052 13.6 0.1 6.9 6.7 0.0 2.2 2 0 0 2 2 2 0 Vaculolar membrane protein DUF3481 PF11980.3 EIW81184.1 - 0.058 13.2 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) LRR19-TM PF15176.1 EIW81184.1 - 0.073 12.7 0.2 0.17 11.5 0.1 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain EphA2_TM PF14575.1 EIW81184.1 - 0.11 12.9 0.0 0.39 11.1 0.0 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 EIW81184.1 - 0.77 9.3 8.5 1.5 8.4 5.9 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Zn_clus PF00172.13 EIW81185.1 - 0.015 15.1 8.5 0.13 12.1 0.4 2.4 1 1 1 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Na_H_Exchanger PF00999.16 EIW81186.1 - 3.8e-64 216.5 49.0 5.6e-64 216.0 34.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FAD_binding_3 PF01494.14 EIW81187.1 - 2.2e-16 59.8 1.2 1.7e-07 30.6 0.2 2.4 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EIW81187.1 - 0.0051 16.8 0.1 0.011 15.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EIW81187.1 - 0.014 15.1 1.3 2.4 7.9 0.1 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding LRR_8 PF13855.1 EIW81188.1 - 0.0025 17.5 0.3 0.56 10.0 0.2 3.6 3 1 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.2 EIW81188.1 - 0.0077 15.8 0.3 1.7 8.3 0.3 3.8 4 2 1 5 5 5 2 Leucine Rich repeats (2 copies) 4HBT_3 PF13622.1 EIW81189.1 - 6.1e-26 91.6 1.4 1e-25 90.9 1.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily PLDc_2 PF13091.1 EIW81191.1 - 2.6e-16 59.4 0.0 2.7e-08 33.6 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EIW81191.1 - 0.023 14.4 4.4 0.066 13.0 0.0 2.9 3 0 0 3 3 3 0 Phospholipase D Active site motif BTB PF00651.26 EIW81192.1 - 0.0032 17.4 0.0 0.0075 16.2 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Asp PF00026.18 EIW81193.1 - 1.8e-47 162.1 19.9 2.9e-47 161.4 13.8 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW81193.1 - 3.9e-06 26.9 9.7 7.6e-06 25.9 3.5 3.3 2 1 1 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIW81193.1 - 0.064 13.7 10.0 0.34 11.4 1.0 3.8 4 1 0 4 4 4 0 Aspartyl protease TAXi_C PF14541.1 EIW81193.1 - 0.076 12.5 2.4 0.14 11.7 0.3 2.3 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal NicO PF03824.11 EIW81193.1 - 1.1 8.4 4.4 1.8 7.7 3.1 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein Asp PF00026.18 EIW81194.1 - 2e-48 165.2 16.1 3.3e-48 164.5 11.2 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW81194.1 - 1.2e-06 28.6 4.7 1.7e-06 28.0 1.0 2.7 2 1 1 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIW81194.1 - 0.0004 20.8 3.4 0.065 13.7 0.4 2.7 2 0 0 2 2 2 2 Aspartyl protease RVP_2 PF08284.6 EIW81194.1 - 0.035 14.0 0.0 2 8.3 0.0 2.2 2 0 0 2 2 2 0 Retroviral aspartyl protease p450 PF00067.17 EIW81195.1 - 5.1e-63 213.1 0.0 6.1e-63 212.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EIW81196.1 - 7.4e-05 22.4 0.1 0.0002 20.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like NAD_binding_10 PF13460.1 EIW81198.1 - 1.9e-13 50.8 0.3 2.8e-13 50.2 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW81198.1 - 2.4e-09 36.9 0.1 2.1e-07 30.6 0.0 2.5 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIW81198.1 - 0.00011 21.5 0.0 0.00045 19.5 0.1 1.7 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 EIW81198.1 - 0.00035 19.3 0.0 0.044 12.4 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EIW81198.1 - 0.00041 19.4 0.1 0.00055 19.0 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 EIW81198.1 - 0.0033 17.3 0.2 0.0033 17.3 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EIW81198.1 - 0.011 14.6 0.0 0.26 10.1 0.0 2.4 2 1 0 2 2 2 0 RmlD substrate binding domain DapB_N PF01113.15 EIW81198.1 - 0.013 15.3 0.1 0.025 14.5 0.1 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_2 PF03446.10 EIW81198.1 - 0.038 13.8 0.0 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 EIW81198.1 - 0.039 13.9 0.0 0.07 13.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain F420_oxidored PF03807.12 EIW81198.1 - 0.049 14.0 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 EIW81198.1 - 0.076 12.3 0.1 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Asp PF00026.18 EIW81199.1 - 1.8e-13 50.4 1.4 1.1e-11 44.6 1.0 2.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EIW81199.1 - 8.2e-06 26.2 0.4 0.022 15.2 0.3 3.0 2 2 0 2 2 2 2 Aspartyl protease RVP PF00077.15 EIW81199.1 - 0.014 15.2 0.1 0.49 10.3 0.0 2.9 3 0 0 3 3 3 0 Retroviral aspartyl protease gag-asp_proteas PF13975.1 EIW81199.1 - 0.017 14.9 0.1 0.068 13.0 0.1 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease TAXi_N PF14543.1 EIW81199.1 - 0.055 13.4 1.3 0.48 10.3 0.3 2.8 2 2 0 2 2 2 0 Xylanase inhibitor N-terminal MFS_1 PF07690.11 EIW81200.1 - 6.8e-20 71.0 53.9 5.5e-17 61.5 36.3 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Glug PF07581.7 EIW81200.1 - 0.1 12.8 3.7 0.13 12.5 0.0 2.8 2 0 0 2 2 2 0 The GLUG motif Peptidase_S28 PF05577.7 EIW81201.1 - 2.8e-55 187.6 0.0 2.9e-54 184.2 0.0 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 YjeF_N PF03853.10 EIW81203.1 - 3.5e-41 140.6 0.0 4.4e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus PALP PF00291.20 EIW81203.1 - 0.045 12.9 0.0 0.059 12.5 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme zf-MYND PF01753.13 EIW81204.1 - 1.6e-08 34.2 9.4 7.2e-08 32.1 6.5 2.3 1 1 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EIW81204.1 - 8.7e-05 22.3 3.9 0.00035 20.3 2.7 2.1 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Transpos_assoc PF13963.1 EIW81205.1 - 0.12 12.4 0.3 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 Transposase-associated domain Cullin PF00888.17 EIW81206.1 - 8.6e-45 153.3 0.0 1.8e-44 152.3 0.0 1.4 1 0 0 1 1 1 1 Cullin family APC2 PF08672.6 EIW81206.1 - 3.3e-11 43.2 0.0 8.3e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 GDC-P PF02347.11 EIW81206.1 - 0.056 12.1 0.0 0.088 11.4 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein Ribonuc_red_lgC PF02867.10 EIW81208.1 - 1.8e-210 700.0 0.0 2.4e-210 699.6 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EIW81208.1 - 5.1e-24 83.8 0.1 1.7e-23 82.1 0.0 2.0 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EIW81208.1 - 1.1e-13 51.4 0.4 4e-13 49.6 0.1 2.2 2 0 0 2 2 2 1 ATP cone domain VAD1-2 PF15310.1 EIW81208.1 - 0.096 12.3 2.8 0.16 11.6 2.0 1.2 1 0 0 1 1 1 0 Vitamin A-deficiency (VAD) rat model signalling BTB PF00651.26 EIW81209.1 - 0.00084 19.3 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain COX6B PF02297.12 EIW81209.1 - 0.096 12.7 0.3 0.19 11.7 0.2 1.4 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Pap_E4 PF02711.9 EIW81209.1 - 0.22 12.3 2.3 0.41 11.5 1.6 1.4 1 0 0 1 1 1 0 E4 protein Aldo_ket_red PF00248.16 EIW81210.1 - 3.3e-43 147.5 0.0 4.6e-43 147.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Abhydrolase_3 PF07859.8 EIW81211.1 - 1.1e-13 51.3 0.0 6.8e-09 35.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIW81211.1 - 1e-10 41.2 0.2 0.00024 20.3 0.0 2.3 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIW81211.1 - 1.8e-10 40.7 0.0 5.5e-10 39.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EIW81211.1 - 6.3e-05 21.9 0.0 8.2e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 EIW81211.1 - 0.00017 21.5 0.6 0.00032 20.6 0.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EIW81211.1 - 0.00025 20.3 0.1 0.061 12.5 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family Peptidase_S15 PF02129.13 EIW81211.1 - 0.012 15.0 0.0 0.14 11.5 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF2048 PF09752.4 EIW81211.1 - 0.051 12.4 0.1 0.073 11.9 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Abhydrolase_2 PF02230.11 EIW81211.1 - 0.052 12.9 0.0 0.11 11.8 0.0 1.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Patatin PF01734.17 EIW81211.1 - 0.097 12.5 0.4 0.2 11.5 0.3 1.4 1 1 0 1 1 1 0 Patatin-like phospholipase PA14 PF07691.7 EIW81212.1 - 0.11 12.1 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 PA14 domain Avl9 PF09794.4 EIW81213.1 - 8.1e-127 422.8 0.0 9.3e-127 422.6 0.0 1.0 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 EIW81213.1 - 2.2e-09 37.0 0.0 0.0002 21.0 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 EIW81213.1 - 8e-09 35.1 0.4 0.0033 16.7 0.0 3.1 3 0 0 3 3 3 3 Uncharacterized conserved protein (DUF2347) MFS_1 PF07690.11 EIW81214.1 - 2.2e-20 72.6 50.3 5.3e-20 71.4 33.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.20 EIW81215.1 - 8.3e-66 221.7 0.0 9.9e-66 221.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW81215.1 - 7.9e-36 123.4 0.0 1.5e-35 122.5 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW81215.1 - 6.4e-05 22.0 0.0 0.00011 21.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EIW81215.1 - 0.0014 17.4 0.0 0.0024 16.7 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.17 EIW81215.1 - 0.035 13.4 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 RIO1 family AMPKBI PF04739.10 EIW81216.1 - 1.8e-22 79.0 0.0 5.6e-22 77.5 0.0 1.9 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain TcdB_toxin_midN PF12256.3 EIW81216.1 - 0.064 12.7 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Insecticide toxin TcdB middle/N-terminal region DUF1777 PF08648.7 EIW81216.1 - 1.9 8.2 20.9 0.081 12.6 8.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) A_deaminase PF00962.17 EIW81217.1 - 9.2e-109 363.3 1.4 1.2e-108 362.9 0.9 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase DUF2235 PF09994.4 EIW81218.1 - 1.2e-76 257.7 0.1 1.5e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EIW81218.1 - 0.043 13.5 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family BHD_3 PF10405.4 EIW81219.1 - 9.8e-27 92.4 0.1 2.2e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 EIW81219.1 - 3.1e-22 78.5 0.0 3.1e-22 78.5 0.0 2.0 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 EIW81219.1 - 5.4e-17 61.0 0.0 7.5e-16 57.3 0.0 2.5 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EIW81219.1 - 1.3e-13 51.0 0.0 1.3e-13 51.0 0.0 3.8 4 0 0 4 4 4 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EIW81219.1 - 2e-05 24.7 0.2 0.00012 22.2 0.0 2.5 1 1 1 2 2 2 1 Transglutaminase-like superfamily GCD14 PF08704.5 EIW81220.1 - 5.3e-93 311.0 0.2 1.6e-92 309.4 0.1 1.6 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_26 PF13659.1 EIW81220.1 - 4.6e-06 26.6 0.0 7.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIW81220.1 - 1.2e-05 24.9 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EIW81220.1 - 9.6e-05 22.9 0.0 0.00016 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW81220.1 - 0.00017 21.1 0.0 0.00026 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EIW81220.1 - 0.00049 20.8 0.3 0.0012 19.6 0.1 1.8 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.9 EIW81220.1 - 0.0021 17.4 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Fibrillarin PF01269.12 EIW81220.1 - 0.0048 15.8 0.0 0.0093 14.9 0.0 1.4 1 0 0 1 1 1 1 Fibrillarin RrnaAD PF00398.15 EIW81220.1 - 0.0076 15.3 0.0 0.022 13.8 0.0 1.6 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_23 PF13489.1 EIW81220.1 - 0.036 13.7 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EIW81220.1 - 0.075 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PAS_3 PF08447.6 EIW81221.1 - 5.6e-08 32.7 0.0 1.3e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EIW81221.1 - 2.2e-05 24.2 0.0 0.00014 21.6 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.1 EIW81221.1 - 2.4e-05 24.2 0.0 0.0019 18.1 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS_9 PF13426.1 EIW81221.1 - 7.3e-05 23.0 0.0 0.004 17.4 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 EIW81221.1 - 0.098 12.7 0.0 0.42 10.6 0.0 2.0 3 0 0 3 3 3 0 PAS fold FYRN PF05964.9 EIW81222.1 - 6.1e-18 64.0 0.4 1e-17 63.3 0.3 1.4 1 0 0 1 1 1 1 F/Y-rich N-terminus FYRC PF05965.9 EIW81222.1 - 2e-15 56.3 0.0 3.7e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 F/Y rich C-terminus Di19_C PF14571.1 EIW81222.1 - 0.018 15.3 0.3 0.059 13.6 0.2 2.0 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal LRR_4 PF12799.2 EIW81224.1 - 0.00016 21.1 4.2 4.3 7.0 0.0 5.5 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW81224.1 - 0.00027 20.6 0.7 8.9 6.1 0.0 4.4 3 1 0 3 3 3 2 Leucine rich repeat F-box-like PF12937.2 EIW81224.1 - 0.00081 19.0 0.0 0.0026 17.4 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 EIW81224.1 - 0.7 10.1 4.8 28 5.1 0.0 5.1 6 0 0 6 6 6 0 Leucine Rich repeat Helicase_C PF00271.26 EIW81225.1 - 1.6e-17 63.1 0.0 3.9e-15 55.4 0.0 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.24 EIW81225.1 - 2.2e-13 50.0 0.0 4.7e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase MDFI PF15316.1 EIW81225.1 - 2.7 7.9 7.8 13 5.7 1.1 3.2 2 1 1 3 3 3 0 MyoD family inhibitor COesterase PF00135.23 EIW81226.1 - 2.1e-89 300.6 0.0 2.9e-89 300.2 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW81226.1 - 4e-06 26.5 0.4 8.7e-06 25.4 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 EIW81227.1 - 1.8e-89 300.8 0.0 2.4e-89 300.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW81227.1 - 7.3e-11 42.0 0.0 7.3e-11 42.0 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIW81227.1 - 0.00051 19.3 0.2 0.0012 18.0 0.1 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIW81227.1 - 0.00054 19.7 0.1 0.0011 18.7 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family SH3_1 PF00018.23 EIW81228.1 - 4.3e-08 32.4 0.0 9.8e-08 31.2 0.0 1.6 1 1 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIW81228.1 - 3.4e-05 23.3 0.0 5.9e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIW81228.1 - 0.00013 21.3 0.0 0.00023 20.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain MAGE_N PF12440.3 EIW81228.1 - 1.9 8.8 4.8 2.9 8.2 3.3 1.3 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal YTH PF04146.10 EIW81230.1 - 4.9e-48 162.2 0.0 1.2e-47 161.0 0.0 1.6 1 1 0 1 1 1 1 YT521-B-like domain RRM_1 PF00076.17 EIW81230.1 - 8.5e-06 25.3 0.0 3.8e-05 23.2 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW81230.1 - 0.00029 20.7 0.0 0.00057 19.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW81230.1 - 0.0021 17.8 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) F-box PF00646.28 EIW81231.1 - 6.7e-07 28.8 0.0 1.5e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW81231.1 - 3.2e-05 23.5 0.1 9e-05 22.1 0.1 1.9 1 0 0 1 1 1 1 F-box-like Cep57_MT_bd PF06657.8 EIW81232.1 - 2.2e-17 62.7 0.0 2.2e-17 62.7 0.0 3.7 3 0 0 3 3 3 1 Centrosome microtubule-binding domain of Cep57 Cep57_CLD_2 PF14197.1 EIW81232.1 - 8.1e-08 32.1 6.3 8.1e-08 32.1 4.3 4.1 4 1 0 4 4 4 1 Centrosome localisation domain of PPC89 IncA PF04156.9 EIW81232.1 - 0.0042 16.6 17.5 0.031 13.8 3.9 3.0 3 0 0 3 3 3 2 IncA protein DUF4201 PF13870.1 EIW81232.1 - 0.028 13.8 11.0 0.12 11.8 1.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Mnd1 PF03962.10 EIW81232.1 - 0.091 12.4 11.3 0.029 14.0 0.7 2.7 2 0 0 2 2 2 0 Mnd1 family DivIC PF04977.10 EIW81232.1 - 0.14 11.7 6.5 5 6.6 0.1 2.9 2 0 0 2 2 2 0 Septum formation initiator Spc7 PF08317.6 EIW81232.1 - 0.21 10.2 9.8 0.66 8.5 1.5 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein HTH_33 PF13592.1 EIW81232.1 - 0.25 10.9 2.3 0.24 10.9 0.1 2.0 2 0 0 2 2 2 0 Winged helix-turn helix Sec20 PF03908.8 EIW81232.1 - 0.37 10.5 1.7 7.4 6.3 0.1 3.0 3 0 0 3 3 2 0 Sec20 Herpes_UL6 PF01763.11 EIW81232.1 - 0.59 8.2 3.7 0.82 7.7 2.2 1.5 1 1 0 1 1 1 0 Herpesvirus UL6 like TPR_MLP1_2 PF07926.7 EIW81232.1 - 0.93 9.2 13.9 4.6 7.0 0.9 3.5 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein CorA PF01544.13 EIW81232.1 - 0.99 8.3 10.1 0.12 11.3 2.2 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF972 PF06156.8 EIW81232.1 - 2.3 8.5 10.0 1.5 9.1 0.5 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF1342 PF07072.6 EIW81232.1 - 2.6 7.6 8.9 4.5 6.8 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1342) COG2 PF06148.6 EIW81232.1 - 3.3 7.5 9.3 3.3 7.5 1.0 3.2 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cortex-I_coil PF09304.5 EIW81232.1 - 3.8 7.6 21.6 0.047 13.7 3.1 3.5 3 0 0 3 3 3 0 Cortexillin I, coiled coil Cep57_CLD PF14073.1 EIW81232.1 - 3.9 7.2 18.9 0.56 10.0 8.6 2.8 2 1 1 3 3 3 0 Centrosome localisation domain of Cep57 TMF_TATA_bd PF12325.3 EIW81232.1 - 5 6.8 18.3 1.2 8.8 2.0 3.6 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Spc24 PF08286.6 EIW81232.1 - 8.4 6.1 8.1 2.1 8.0 1.2 2.8 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 DUF663 PF04950.7 EIW81233.1 - 2.2e-90 302.6 0.0 2.2e-90 302.6 0.0 1.9 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EIW81233.1 - 6.5e-29 99.3 0.0 1.5e-28 98.1 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EIW81233.1 - 5.2e-07 29.2 0.0 0.00038 19.9 0.0 2.5 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EIW81233.1 - 1.8e-05 24.8 0.0 4.8e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW81233.1 - 4.4e-05 24.2 0.0 4.4e-05 24.2 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EIW81233.1 - 6.9e-05 22.9 0.0 0.0002 21.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain MobB PF03205.9 EIW81233.1 - 0.00016 21.3 1.0 0.0013 18.4 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.24 EIW81233.1 - 0.00082 19.5 0.0 0.0021 18.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EIW81233.1 - 0.00099 19.0 0.1 0.0034 17.3 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EIW81233.1 - 0.0011 19.2 0.0 0.0011 19.2 0.0 2.4 2 0 0 2 2 2 1 ABC transporter PduV-EutP PF10662.4 EIW81233.1 - 0.0013 18.1 0.5 0.0067 15.9 0.0 2.3 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EIW81233.1 - 0.0016 18.1 1.3 0.0023 17.6 0.0 1.8 2 0 0 2 2 1 1 NACHT domain AAA_24 PF13479.1 EIW81233.1 - 0.0018 17.8 0.1 0.0047 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIW81233.1 - 0.0022 18.2 0.0 0.0022 18.2 0.0 2.8 2 0 0 2 2 1 1 AAA domain Miro PF08477.8 EIW81233.1 - 0.0026 18.2 1.6 0.0083 16.6 0.0 2.4 2 0 0 2 2 2 1 Miro-like protein AAA_14 PF13173.1 EIW81233.1 - 0.0051 16.7 0.0 0.015 15.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EIW81233.1 - 0.0064 15.9 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA-like domain AAA_19 PF13245.1 EIW81233.1 - 0.0068 16.1 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain NB-ARC PF00931.17 EIW81233.1 - 0.0075 15.1 0.0 0.013 14.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NTPase_1 PF03266.10 EIW81233.1 - 0.0098 15.6 0.2 0.024 14.3 0.1 1.6 1 0 0 1 1 1 1 NTPase AAA_25 PF13481.1 EIW81233.1 - 0.01 15.2 0.0 0.035 13.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 EIW81233.1 - 0.01 15.9 0.0 0.028 14.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase cobW PF02492.14 EIW81233.1 - 0.012 15.0 0.1 0.023 14.1 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EIW81233.1 - 0.012 15.4 0.0 0.012 15.4 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.1 EIW81233.1 - 0.019 14.9 0.1 0.019 14.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EIW81233.1 - 0.038 13.1 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 EIW81233.1 - 0.048 13.3 0.1 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.1 EIW81233.1 - 0.08 12.8 0.6 0.56 10.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EIW81233.1 - 0.94 9.7 0.0 0.94 9.7 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.1 EIW81233.1 - 0.99 8.9 6.1 2.2 7.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Nipped-B_C PF12830.2 EIW81234.1 - 8.4e-50 169.0 1.8 8.4e-50 169.0 1.2 2.9 3 0 0 3 3 3 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EIW81234.1 - 3.9e-12 45.8 0.8 3.9e-12 45.8 0.6 3.5 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.17 EIW81234.1 - 1.5e-05 24.6 2.3 0.36 11.0 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 EIW81234.1 - 0.0002 21.6 11.6 0.0025 18.0 0.2 5.4 5 1 1 6 6 6 1 HEAT repeats Cnd1 PF12717.2 EIW81234.1 - 0.0024 17.7 0.1 0.084 12.7 0.0 2.9 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 FANCI_S2 PF14676.1 EIW81234.1 - 0.0027 17.6 2.8 0.021 14.7 0.1 3.7 4 0 0 4 4 4 1 FANCI solenoid 2 HEAT_EZ PF13513.1 EIW81234.1 - 0.0032 17.8 8.3 2.9 8.5 0.2 5.4 3 1 1 4 4 4 2 HEAT-like repeat TPR_11 PF13414.1 EIW81235.1 - 4.7e-19 67.7 0.7 1.5e-15 56.6 0.0 2.3 1 1 1 2 2 2 2 TPR repeat RPAP3_C PF13877.1 EIW81235.1 - 1.6e-17 63.2 0.5 2.5e-17 62.6 0.3 1.3 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_1 PF00515.23 EIW81235.1 - 2.1e-13 49.2 2.0 2.3e-05 23.8 0.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIW81235.1 - 6e-13 49.0 0.9 1.9e-09 37.9 0.5 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIW81235.1 - 9.2e-11 40.8 2.5 0.0024 17.6 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIW81235.1 - 1.9e-08 34.4 0.0 6.7e-08 32.7 0.0 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EIW81235.1 - 1e-07 31.5 0.4 0.016 15.3 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIW81235.1 - 2.6e-06 27.5 0.2 0.00083 19.7 0.0 3.3 2 1 2 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIW81235.1 - 0.0016 18.0 0.2 2.8 7.9 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EIW81235.1 - 0.0019 18.0 0.0 0.0063 16.3 0.0 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 EIW81235.1 - 0.0056 16.3 0.5 1.1 9.1 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIW81235.1 - 0.018 14.8 0.2 0.094 12.6 0.0 2.3 2 1 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.1 EIW81235.1 - 0.095 12.6 0.5 2.8 7.9 0.2 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat Apc3 PF12895.2 EIW81235.1 - 0.1 12.7 0.0 0.82 9.8 0.0 1.9 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EIW81235.1 - 1.1 9.8 6.1 11 6.7 0.0 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat Peptidase_M20 PF01546.23 EIW81236.1 - 6.9e-29 100.6 0.0 1.2e-28 99.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EIW81236.1 - 1.1e-21 75.8 5.5 1.4e-07 31.1 0.0 7.1 6 0 0 6 6 6 4 WD domain, G-beta repeat M20_dimer PF07687.9 EIW81236.1 - 7.9e-12 44.9 0.0 1.4e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain ADH_N PF08240.7 EIW81237.1 - 6.3e-24 83.8 0.1 1.2e-23 82.9 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW81237.1 - 7.8e-09 35.1 0.0 1.9e-08 33.9 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase NADH_4Fe-4S PF10589.4 EIW81237.1 - 2.1 7.5 6.9 5.1 6.3 4.8 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SMC_N PF02463.14 EIW81238.1 - 5.2e-70 235.1 1.8 9.5e-70 234.2 1.3 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EIW81238.1 - 5.2e-29 100.6 0.3 4.8e-28 97.5 0.0 2.9 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EIW81238.1 - 4.2e-16 59.8 16.3 4.2e-16 59.8 11.3 5.7 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.1 EIW81238.1 - 6.8e-15 55.7 1.4 6.9e-07 29.5 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EIW81238.1 - 0.0006 19.2 0.0 0.0015 18.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EIW81238.1 - 0.0051 17.1 0.1 0.045 14.0 0.1 5.4 4 2 1 5 5 5 2 ABC transporter DUF87 PF01935.12 EIW81238.1 - 1.2 8.8 0.0 1.2 8.8 0.0 6.0 3 2 2 6 6 6 0 Domain of unknown function DUF87 AAA_13 PF13166.1 EIW81238.1 - 3.1 6.1 76.5 0.72 8.2 0.0 5.5 3 2 1 5 5 5 0 AAA domain Ribosomal_L23eN PF03939.8 EIW81239.1 - 5e-20 71.2 11.6 5e-20 71.2 8.1 2.4 2 2 1 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EIW81239.1 - 7.8e-19 67.4 2.2 1.7e-18 66.3 1.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L23 YihI PF04220.7 EIW81239.1 - 0.00051 19.4 0.3 0.0007 18.9 0.2 1.1 1 0 0 1 1 1 1 Der GTPase activator (YihI) ASL_C PF08328.6 EIW81239.1 - 0.092 12.5 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminal Rax2 PF12768.2 EIW81240.1 - 0.021 14.0 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity EHN PF06441.7 EIW81241.1 - 1.4e-31 108.6 0.1 8.5e-31 106.1 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EIW81241.1 - 1.4e-06 28.3 3.9 1.1e-05 25.4 2.1 3.1 3 1 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW81241.1 - 0.0014 18.2 0.0 0.0026 17.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold RasGEF PF00617.14 EIW81242.1 - 2e-55 187.4 0.0 1.1e-54 185.0 0.0 2.0 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EIW81242.1 - 6.7e-20 71.1 0.3 1.5e-19 69.9 0.2 1.7 1 0 0 1 1 1 1 RasGEF N-terminal motif Spexin PF15171.1 EIW81242.1 - 0.057 13.4 0.5 0.17 11.9 0.3 1.7 1 0 0 1 1 1 0 Neuropeptide secretory protein family, NPQ, spexin RRM_1 PF00076.17 EIW81243.1 - 1e-08 34.6 0.0 1.7e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW81243.1 - 3.1e-07 30.2 0.0 5.4e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIW81243.1 - 0.00026 20.7 0.0 0.00042 20.0 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EIW81243.1 - 0.00062 19.5 0.1 0.0016 18.2 0.0 1.7 2 0 0 2 2 2 1 RNA binding motif RRM_5 PF13893.1 EIW81243.1 - 0.0068 16.2 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MYT1 PF08474.6 EIW81243.1 - 0.012 15.1 4.9 0.018 14.5 3.4 1.3 1 0 0 1 1 1 0 Myelin transcription factor 1 LRR_4 PF12799.2 EIW81244.1 - 1.2e-31 107.7 40.0 1.2e-06 27.9 0.1 9.1 7 2 4 11 11 11 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW81244.1 - 2.7e-25 87.8 35.8 4.6e-08 32.7 1.5 6.8 4 1 4 8 8 8 7 Leucine rich repeat LRR_7 PF13504.1 EIW81244.1 - 4.4e-13 47.1 37.2 1.2 9.6 0.1 13.2 13 0 0 13 13 13 6 Leucine rich repeat LRR_1 PF00560.28 EIW81244.1 - 1.4e-12 45.7 36.2 0.34 11.0 0.2 12.3 9 2 3 12 12 12 6 Leucine Rich Repeat LRR_9 PF14580.1 EIW81244.1 - 3.5e-09 36.4 9.8 0.12 11.8 0.6 4.2 2 1 1 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.1 EIW81244.1 - 1.3e-06 27.8 30.9 0.39 10.9 0.3 10.6 10 2 2 12 12 12 3 Leucine Rich repeat Homeobox_KN PF05920.6 EIW81245.1 - 3.8e-19 68.0 4.6 1.8e-17 62.7 0.1 3.1 3 0 0 3 3 3 2 Homeobox KN domain Homeobox PF00046.24 EIW81245.1 - 2.3e-05 23.9 0.0 4.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Homeobox domain p450 PF00067.17 EIW81246.1 - 4e-51 173.9 0.0 7.6e-51 173.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_32 PF13679.1 EIW81247.1 - 1e-17 64.0 2.0 4.3e-17 62.1 1.4 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW81247.1 - 0.02 15.3 0.0 0.042 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EIW81247.1 - 0.022 14.3 0.0 0.058 12.9 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 EIW81247.1 - 0.033 14.7 0.0 0.076 13.5 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EIW81247.1 - 0.079 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain cobW PF02492.14 EIW81248.1 - 1.1e-31 109.6 0.0 1.4e-31 109.3 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.18 EIW81248.1 - 7.5e-05 22.6 0.1 0.00042 20.2 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase ArgK PF03308.11 EIW81248.1 - 0.00013 20.8 0.1 0.048 12.4 0.0 2.1 2 0 0 2 2 2 2 ArgK protein GTP_EFTU PF00009.22 EIW81248.1 - 0.0015 17.9 0.3 0.16 11.3 0.2 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EIW81248.1 - 0.015 15.5 0.0 0.025 14.8 0.0 1.3 1 0 0 1 1 1 0 ABC transporter TIP49 PF06068.8 EIW81248.1 - 0.021 13.5 0.0 0.03 13.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_18 PF13238.1 EIW81248.1 - 0.023 15.0 0.1 0.037 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EIW81248.1 - 0.027 15.2 0.8 0.049 14.4 0.1 2.0 2 1 0 2 2 1 0 AAA domain IstB_IS21 PF01695.12 EIW81248.1 - 0.048 13.0 0.0 0.078 12.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SE PF00437.15 EIW81248.1 - 0.054 12.3 0.0 0.091 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 EIW81248.1 - 0.069 13.1 0.1 0.1 12.5 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 EIW81248.1 - 0.083 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 EIW81248.1 - 0.086 12.2 0.2 0.29 10.5 0.1 1.7 1 1 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EIW81248.1 - 0.09 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 APS_kinase PF01583.15 EIW81248.1 - 0.12 12.0 0.0 0.7 9.5 0.0 2.1 2 0 0 2 2 2 0 Adenylylsulphate kinase His_Phos_2 PF00328.17 EIW81249.1 - 2.5e-08 33.6 0.3 7.6e-07 28.7 0.2 2.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EIW81249.1 - 0.16 12.0 0.0 0.22 11.5 0.0 1.4 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) HCO3_cotransp PF00955.16 EIW81250.1 - 1.9e-55 188.5 8.6 5.8e-30 104.4 0.7 3.0 2 1 1 3 3 3 3 HCO3- transporter family DUF3565 PF12088.3 EIW81250.1 - 0.024 14.3 0.2 0.054 13.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3565) Abhydrolase_6 PF12697.2 EIW81251.1 - 8e-17 61.8 0.3 1.7e-16 60.7 0.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW81251.1 - 1.9e-16 60.1 0.0 3.4e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW81251.1 - 5.4e-09 35.9 0.0 4.8e-07 29.5 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.8 EIW81251.1 - 2.6e-06 27.1 0.0 4.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF818 PF05677.7 EIW81251.1 - 0.00021 20.1 0.0 0.00032 19.5 0.0 1.2 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Peptidase_S9 PF00326.16 EIW81251.1 - 0.0024 17.1 0.1 0.09 11.9 0.0 2.7 1 1 1 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EIW81251.1 - 0.0035 16.7 0.0 0.12 11.7 0.0 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.15 EIW81251.1 - 0.014 15.6 0.0 0.025 14.8 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Lipase_3 PF01764.20 EIW81251.1 - 0.019 14.5 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.3 EIW81251.1 - 0.034 13.9 0.0 0.071 12.9 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_2 PF02230.11 EIW81251.1 - 0.076 12.4 0.0 6.4 6.1 0.0 3.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DUF3089 PF11288.3 EIW81251.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) PHY PF00360.15 EIW81252.1 - 4.8e-23 81.2 0.0 8.9e-23 80.3 0.0 1.4 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 EIW81252.1 - 5.1e-23 80.9 0.1 1.3e-22 79.6 0.0 1.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EIW81252.1 - 2.8e-18 65.9 0.0 3.3e-17 62.4 0.0 2.4 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.21 EIW81252.1 - 1.8e-17 63.8 0.1 1.6e-16 60.7 0.1 2.4 2 0 0 2 2 2 1 GAF domain HisKA PF00512.20 EIW81252.1 - 3.5e-11 42.9 1.3 9.2e-11 41.5 0.9 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 EIW81252.1 - 3.6e-10 40.2 0.0 1.1e-09 38.7 0.0 1.9 1 0 0 1 1 1 1 PAS fold OKR_DC_1_N PF03709.10 EIW81252.1 - 0.038 14.0 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain HATPase_c_2 PF13581.1 EIW81252.1 - 0.056 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.1 EIW81252.1 - 0.069 12.8 0.1 0.23 11.1 0.0 1.9 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF202 PF02656.10 EIW81253.1 - 2.2e-19 69.4 1.7 2.2e-19 69.4 1.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF202) YppG PF14179.1 EIW81253.1 - 0.54 10.8 1.9 0.73 10.4 1.3 1.2 1 0 0 1 1 1 0 YppG-like protein DUF2975 PF11188.3 EIW81253.1 - 0.91 9.2 8.5 2.6 7.7 5.9 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) Transket_pyr PF02779.19 EIW81255.1 - 1.5e-65 219.9 0.0 2.4e-65 219.3 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EIW81255.1 - 4.2e-56 189.8 0.0 6.5e-56 189.2 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Transposase_21 PF02992.9 EIW81256.1 - 0.012 14.6 0.1 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Transposase family tnp2 Anillin PF08174.6 EIW81263.1 - 0.018 15.0 0.3 0.78 9.7 0.0 2.3 2 0 0 2 2 2 0 Cell division protein anillin DUF2229 PF09989.4 EIW81263.1 - 0.21 11.0 4.3 0.64 9.4 3.0 1.8 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) UBN2_2 PF14227.1 EIW81266.1 - 8.6e-07 28.5 0.0 2.5e-06 27.0 0.0 1.7 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIW81266.1 - 8.9e-06 25.4 0.0 1.8e-05 24.4 0.0 1.5 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type RVT_2 PF07727.9 EIW81267.1 - 2.4e-15 56.1 0.0 2.5e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FLgD_tudor PF13861.1 EIW81268.1 - 0.0028 17.6 3.5 0.021 14.8 0.6 2.6 2 1 1 3 3 3 2 FlgD Tudor-like domain R_equi_Vir PF05526.6 EIW81269.1 - 0.048 13.3 0.3 0.086 12.4 0.1 1.5 1 1 1 2 2 2 0 Rhodococcus equi virulence-associated protein DDE_3 PF13358.1 EIW81271.1 - 4.4e-08 32.9 0.0 0.00089 19.0 0.0 2.4 2 0 0 2 2 2 2 DDE superfamily endonuclease PRNT PF15174.1 EIW81271.1 - 0.052 13.2 0.3 0.33 10.6 0.2 2.1 2 0 0 2 2 2 0 Prion-related protein testis-specific Se-cys_synth_N PF12390.3 EIW81273.1 - 0.11 12.6 0.1 0.26 11.4 0.1 1.6 1 0 0 1 1 1 0 Selenocysteine synthase N terminal Transposase_21 PF02992.9 EIW81274.1 - 4.1e-07 29.3 0.1 6.6e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 zf-like PF04071.7 EIW81275.1 - 0.011 15.3 1.0 0.015 14.9 0.7 1.2 1 0 0 1 1 1 0 Cysteine-rich small domain DUF659 PF04937.10 EIW81276.1 - 8e-05 22.1 0.1 0.00012 21.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) Herpes_UL16 PF03044.9 EIW81276.1 - 0.017 14.1 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL16/UL94 family Transposase_21 PF02992.9 EIW81277.1 - 0.00052 19.1 0.7 0.0009 18.3 0.1 1.7 2 0 0 2 2 2 1 Transposase family tnp2 Snapin_Pallidin PF14712.1 EIW81278.1 - 0.1 12.9 1.2 0.21 11.9 0.8 1.4 1 0 0 1 1 1 0 Snapin/Pallidin Nop14 PF04147.7 EIW81278.1 - 5.3 4.8 36.2 8.4 4.1 25.1 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EIW81278.1 - 6.7 5.8 32.2 0.78 8.9 16.3 2.4 2 0 0 2 2 2 0 SDA1 Helicase_C_2 PF13307.1 EIW81280.1 - 2.7e-50 170.5 0.0 1.7e-49 167.9 0.0 2.2 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 EIW81280.1 - 1.1e-39 135.5 0.0 2.6e-37 127.8 0.0 2.3 1 1 0 1 1 1 1 DEAD_2 AAA_22 PF13401.1 EIW81280.1 - 0.0023 18.0 0.1 5 7.2 0.1 3.1 3 0 0 3 3 3 2 AAA domain DEAD PF00270.24 EIW81280.1 - 0.0047 16.4 0.0 0.098 12.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EIW81280.1 - 0.0082 15.9 0.0 1.2 8.9 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EIW81280.1 - 0.015 15.0 0.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain PhoH PF02562.11 EIW81280.1 - 0.038 13.2 0.0 0.54 9.4 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein eIF-3c_N PF05470.7 EIW81280.1 - 0.053 11.6 4.8 0.079 11.0 3.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Hpt PF01627.18 EIW81281.1 - 9.5e-12 44.7 0.1 1.7e-11 43.9 0.1 1.4 1 0 0 1 1 1 1 Hpt domain Sigma70_ner PF04546.8 EIW81281.1 - 1.1 8.8 7.3 0.55 9.8 3.6 1.5 2 0 0 2 2 2 0 Sigma-70, non-essential region CoA_transf_3 PF02515.12 EIW81282.1 - 4.3e-65 218.5 0.0 5.7e-65 218.1 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Transcrip_act PF04949.8 EIW81283.1 - 0.57 9.8 5.1 0.34 10.5 0.6 2.2 2 0 0 2 2 2 0 Transcriptional activator Mac PF12464.3 EIW81283.1 - 1.2 9.1 4.4 2.6 8.1 1.8 2.3 2 0 0 2 2 2 0 Maltose acetyltransferase Na_Ca_ex PF01699.19 EIW81284.1 - 1.9e-23 82.5 37.1 2.4e-14 53.1 6.7 3.1 3 1 0 3 3 3 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EIW81284.1 - 6.5e-11 42.4 9.2 6.5e-11 42.4 6.3 3.5 2 0 0 2 2 2 1 Domain of unknown function (DUF307) MIP-T3 PF10243.4 EIW81284.1 - 1 7.7 8.2 1.6 7.1 5.7 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Ebola_NP PF05505.7 EIW81284.1 - 4.2 5.3 6.8 6.3 4.7 4.7 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein Nop14 PF04147.7 EIW81284.1 - 6.2 4.6 7.8 8.2 4.2 5.4 1.1 1 0 0 1 1 1 0 Nop14-like family CPSF_A PF03178.10 EIW81285.1 - 2.3e-56 191.2 0.0 4.2e-55 187.0 0.0 2.6 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 EIW81285.1 - 5.7e-40 136.9 0.0 1.2e-39 135.8 0.0 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CBFD_NFYB_HMF PF00808.18 EIW81286.1 - 6.5e-13 48.5 0.3 1.1e-12 47.7 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EIW81286.1 - 2.7e-07 30.6 0.2 4e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EIW81286.1 - 0.044 13.5 0.1 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated GST_N_3 PF13417.1 EIW81287.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain HEM4 PF02602.10 EIW81288.1 - 0.095 11.9 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Prothymosin PF03247.9 EIW81289.1 - 0.028 14.5 16.5 0.057 13.5 11.4 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family Tim54 PF11711.3 EIW81289.1 - 0.039 12.5 0.7 0.066 11.7 0.5 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PBP1_TM PF14812.1 EIW81289.1 - 3.4 8.0 8.0 8.7 6.7 5.5 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2890 PF11081.3 EIW81289.1 - 4.2 7.3 10.3 7.9 6.4 7.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF2457 PF10446.4 EIW81289.1 - 5 5.7 14.0 7.8 5.0 9.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) COPI_C PF06957.6 EIW81289.1 - 9.5 4.6 7.8 14 4.0 5.4 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus DASH_Dad1 PF08649.5 EIW81291.1 - 1.5e-15 56.6 0.2 1.8e-15 56.3 0.1 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 DASH_Dad4 PF08650.5 EIW81291.1 - 0.076 12.9 0.0 0.094 12.6 0.0 1.1 1 0 0 1 1 1 0 DASH complex subunit Dad4 RasGEF PF00617.14 EIW81292.1 - 2.4e-57 193.7 0.2 4.4e-57 192.8 0.2 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EIW81292.1 - 3.5e-22 78.4 1.8 3.5e-22 78.4 1.2 2.3 3 0 0 3 3 3 1 RasGEF N-terminal motif SH3_1 PF00018.23 EIW81292.1 - 1.6e-14 53.0 0.1 3.9e-14 51.7 0.1 1.8 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIW81292.1 - 1.3e-12 47.0 0.3 3.6e-12 45.6 0.2 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EIW81292.1 - 2.7e-11 42.7 0.0 6.2e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 EIW81292.1 - 1.5e-05 24.7 0.3 0.013 15.3 0.0 2.8 2 0 0 2 2 2 2 WW domain ATP-synt_G PF04718.10 EIW81292.1 - 0.29 11.8 6.4 4.9 7.8 0.0 3.1 2 0 0 2 2 2 0 Mitochondrial ATP synthase g subunit GTP_EFTU PF00009.22 EIW81293.1 - 1.2e-52 178.1 0.0 1.9e-52 177.4 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EIW81293.1 - 1.6e-14 53.5 0.0 3.2e-14 52.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EIW81293.1 - 7.7e-10 38.4 0.0 1.5e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EIW81293.1 - 8.5e-06 25.7 0.0 2.2e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIW81293.1 - 3.8e-05 23.6 0.0 7.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_IV PF03764.13 EIW81293.1 - 0.0001 21.8 0.0 0.12 11.8 0.0 3.3 3 0 0 3 3 3 2 Elongation factor G, domain IV cobW PF02492.14 EIW81294.1 - 3.9e-45 153.4 0.1 5.4e-45 152.9 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EIW81294.1 - 7.6e-07 28.7 0.0 1.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain GTP_EFTU PF00009.22 EIW81294.1 - 6.2e-05 22.5 0.0 0.0095 15.3 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EIW81294.1 - 0.0079 16.3 0.1 0.034 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EIW81294.1 - 0.014 15.1 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_18 PF13238.1 EIW81294.1 - 0.015 15.5 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EIW81294.1 - 0.016 14.7 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MMR_HSR1 PF01926.18 EIW81294.1 - 0.017 15.1 0.2 0.046 13.6 0.0 2.0 2 1 0 2 2 1 0 50S ribosome-binding GTPase AAA_10 PF12846.2 EIW81294.1 - 0.02 14.3 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 EIW81294.1 - 0.021 14.7 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EIW81294.1 - 0.022 13.5 3.9 0.16 10.6 0.0 3.4 4 0 0 4 4 4 0 ArgK protein AAA_16 PF13191.1 EIW81294.1 - 0.035 14.1 0.1 0.09 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Arf PF00025.16 EIW81294.1 - 0.045 13.0 0.7 1.3 8.2 0.2 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family MobB PF03205.9 EIW81294.1 - 0.06 13.0 0.0 0.35 10.5 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DSPc PF00782.15 EIW81295.1 - 1.8e-26 92.2 0.0 2.5e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EIW81295.1 - 0.003 17.8 0.1 0.044 14.0 0.0 2.2 1 1 1 2 2 2 1 Tyrosine phosphatase family Init_tRNA_PT PF04179.7 EIW81295.1 - 0.011 14.6 0.0 0.011 14.6 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 EIW81295.1 - 0.011 15.0 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase UAA PF08449.6 EIW81296.1 - 2.9e-64 216.8 12.1 2e-63 214.1 8.4 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EIW81296.1 - 5.1e-07 29.7 7.6 5.1e-07 29.7 5.3 4.0 3 2 1 4 4 4 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EIW81296.1 - 1.8e-05 23.9 2.7 0.0066 15.5 0.1 2.2 1 1 1 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 EIW81296.1 - 0.0018 18.4 24.3 0.0083 16.3 4.8 3.6 3 2 0 3 3 3 2 Multidrug resistance efflux transporter TPT PF03151.11 EIW81296.1 - 0.11 12.1 17.5 0.032 13.8 6.1 3.1 3 1 0 3 3 3 0 Triose-phosphate Transporter family UPF0546 PF10639.4 EIW81296.1 - 0.77 9.5 5.0 1.8 8.4 0.6 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 Acetyltransf_4 PF13420.1 EIW81297.1 - 1.8e-21 76.7 0.0 3.4e-21 75.8 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW81297.1 - 2.7e-13 49.7 0.5 4.3e-13 49.1 0.4 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EIW81297.1 - 1.4e-08 34.8 0.0 2.1e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIW81297.1 - 3e-07 30.7 0.0 3.7e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIW81297.1 - 3.6e-07 29.8 0.0 8e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EIW81297.1 - 5e-05 23.3 0.1 7.8e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIW81297.1 - 5.3e-05 23.0 0.0 7.9e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIW81297.1 - 0.0094 15.8 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Mec-17 PF05301.6 EIW81297.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Touch receptor neuron protein Mec-17 Acetyltransf_CG PF14542.1 EIW81297.1 - 0.1 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Yae1_N PF09811.4 EIW81298.1 - 1.1e-13 50.4 1.9 1.7e-13 49.8 1.3 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Tmemb_cc2 PF10267.4 EIW81298.1 - 0.07 11.6 1.4 0.092 11.3 1.0 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF1014 PF06244.7 EIW81298.1 - 0.1 12.8 0.2 0.15 12.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1014) FAD_binding_1 PF00667.15 EIW81299.1 - 6e-55 186.0 0.0 4.7e-54 183.1 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EIW81299.1 - 2.4e-31 108.6 0.7 4.4e-31 107.8 0.5 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EIW81299.1 - 8.6e-23 80.9 0.0 3.4e-22 79.0 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EIW81299.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.7 1 1 0 1 1 1 0 Flavodoxin domain She9_MDM33 PF05546.6 EIW81300.1 - 1.7e-72 243.3 4.8 2.4e-72 242.8 3.3 1.2 1 0 0 1 1 1 1 She9 / Mdm33 family HIT PF01230.18 EIW81301.1 - 1.6e-21 76.6 0.1 3.6e-21 75.5 0.1 1.5 2 0 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EIW81301.1 - 1e-15 57.9 0.0 1.4e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EIW81301.1 - 1.5e-05 24.6 0.2 2.3e-05 24.0 0.2 1.4 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 UPF0172 PF03665.8 EIW81301.1 - 0.11 11.9 1.7 0.12 11.8 0.1 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Phage_int_SAM_1 PF02899.12 EIW81307.1 - 0.13 12.3 0.0 0.31 11.2 0.0 1.6 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain UPF0167 PF03691.9 EIW81308.1 - 0.17 11.2 0.7 0.35 10.2 0.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) Cauli_VI PF01693.11 EIW81310.1 - 1.9e-06 27.8 0.1 3.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Caulimovirus viroplasmin Pkinase PF00069.20 EIW81313.1 - 5.8e-66 222.2 0.0 1.1e-65 221.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW81313.1 - 4.7e-37 127.4 0.0 8.6e-37 126.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HR1 PF02185.11 EIW81313.1 - 1.7e-21 75.6 19.6 1.7e-13 50.0 4.2 2.4 2 0 0 2 2 2 2 Hr1 repeat C1_1 PF00130.17 EIW81313.1 - 2.2e-19 68.9 27.4 5.7e-11 41.9 6.9 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EIW81313.1 - 4.9e-10 39.7 0.4 3e-09 37.2 0.1 2.4 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.25 EIW81313.1 - 7.8e-05 22.4 0.1 0.00018 21.2 0.1 1.6 1 0 0 1 1 1 1 C2 domain Uds1 PF15456.1 EIW81313.1 - 0.029 14.3 18.4 0.018 15.0 1.5 2.7 3 0 0 3 3 3 0 Up-regulated During Septation ARS2 PF04959.8 EIW81313.1 - 0.043 13.9 0.1 0.043 13.9 0.1 2.4 2 1 1 3 3 3 0 Arsenite-resistance protein 2 DUF605 PF04652.11 EIW81313.1 - 4 6.7 16.2 0.17 11.2 3.4 2.3 2 0 0 2 2 2 0 Vta1 like Endosulfine PF04667.12 EIW81314.1 - 4e-19 68.3 0.4 7.8e-19 67.4 0.1 1.7 1 1 1 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region Abhydrolase_3 PF07859.8 EIW81315.1 - 1.4e-62 211.0 0.0 1.8e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EIW81315.1 - 6.4e-09 35.0 0.0 1.4e-08 33.9 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family DUF2424 PF10340.4 EIW81315.1 - 7.9e-06 24.7 0.0 1.1e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_6 PF12697.2 EIW81315.1 - 0.00028 20.8 0.1 0.00047 20.0 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIW81315.1 - 0.00052 19.3 0.0 0.0018 17.5 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIW81315.1 - 0.00068 19.4 0.0 0.00082 19.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EIW81315.1 - 0.015 14.1 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Peptidase_S15 PF02129.13 EIW81315.1 - 0.056 12.8 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) CwfJ_C_1 PF04677.10 EIW81316.1 - 1.4e-31 108.6 0.1 2.2e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EIW81316.1 - 5.9e-25 87.6 0.0 9.1e-23 80.5 0.0 2.5 2 0 0 2 2 2 2 Protein similar to CwfJ C-terminus 2 DUF566 PF04484.7 EIW81316.1 - 3.2 7.1 8.5 5.8 6.3 5.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) G-alpha PF00503.15 EIW81317.1 - 5.1e-124 413.8 0.0 6.3e-124 413.6 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIW81317.1 - 6.4e-09 35.2 0.2 1.7e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family HpcH_HpaI PF03328.9 EIW81318.1 - 1.7e-39 134.9 0.0 2.9e-39 134.2 0.0 1.3 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EIW81318.1 - 4.7e-15 55.2 0.0 1e-08 34.4 0.0 2.2 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold ADH_zinc_N PF00107.21 EIW81319.1 - 5.2e-25 87.4 0.0 7.8e-25 86.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW81319.1 - 2.3e-05 25.2 0.0 4.6e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 EIW81319.1 - 0.047 13.6 0.0 0.095 12.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain ADH_zinc_N PF00107.21 EIW81320.1 - 2.1e-19 69.3 0.1 3.4e-19 68.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW81320.1 - 1.2e-05 26.2 0.0 2.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Peptidase_A4 PF01828.12 EIW81321.1 - 3.7e-67 225.4 17.2 2.8e-49 166.9 2.7 2.1 2 0 0 2 2 2 2 Peptidase A4 family Ig_3 PF13927.1 EIW81321.1 - 0.024 15.1 0.3 0.024 15.1 0.2 2.3 2 1 0 2 2 2 0 Immunoglobulin domain ADH_zinc_N PF00107.21 EIW81322.1 - 1.9e-24 85.6 0.1 3e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW81322.1 - 1.3e-05 26.1 0.0 2.3e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NMO PF03060.10 EIW81322.1 - 0.0021 17.3 0.1 0.018 14.2 0.0 2.0 2 0 0 2 2 2 1 Nitronate monooxygenase TrkA_N PF02254.13 EIW81322.1 - 0.0055 16.7 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.11 EIW81322.1 - 0.079 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF427 PF04248.7 EIW81323.1 - 8.8e-31 105.4 0.1 9.7e-31 105.2 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Mito_carr PF00153.22 EIW81324.1 - 3.4e-75 247.8 2.0 3.4e-25 87.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1469 PF07332.6 EIW81325.1 - 0.0096 15.6 1.6 0.012 15.2 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1469) Melibiase PF02065.13 EIW81325.1 - 0.045 12.4 0.0 0.061 11.9 0.0 1.1 1 0 0 1 1 1 0 Melibiase DUF3328 PF11807.3 EIW81325.1 - 0.089 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Tad PF13400.1 EIW81325.1 - 0.17 11.9 3.4 2.9 7.9 0.5 2.8 2 0 0 2 2 2 0 Putative Flp pilus-assembly TadE/G-like HAMP PF00672.20 EIW81325.1 - 0.21 11.7 1.9 0.47 10.6 1.3 1.5 1 0 0 1 1 1 0 HAMP domain AMP-binding PF00501.23 EIW81327.1 - 5e-86 288.6 0.0 6.4e-86 288.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIW81327.1 - 9.8e-11 42.4 0.4 4.1e-10 40.4 0.2 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 EIW81328.1 - 1.3e-86 290.5 0.0 1.6e-86 290.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIW81328.1 - 5.7e-14 52.8 0.0 1.4e-13 51.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 EIW81329.1 - 2e-82 276.8 0.0 2.6e-82 276.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIW81329.1 - 3e-12 47.2 0.3 1e-11 45.6 0.2 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF667 PF05018.8 EIW81330.1 - 6.8e-14 51.5 0.0 4.1e-05 22.9 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF667) Methyltransf_16 PF10294.4 EIW81331.1 - 1e-11 44.5 0.0 1.2e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase AMP-binding PF00501.23 EIW81332.1 - 1.2e-86 290.7 0.0 1.6e-86 290.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIW81332.1 - 1.6e-13 51.3 0.2 5.2e-13 49.7 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cys_Met_Meta_PP PF01053.15 EIW81334.1 - 6.5e-42 143.1 0.0 8.4e-42 142.8 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EIW81334.1 - 7.5e-06 25.1 0.0 1.8e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class I and II PDE6_gamma PF04868.7 EIW81334.1 - 0.16 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit Ins_beta PF03488.9 EIW81335.1 - 0.0094 15.7 0.5 0.027 14.2 0.0 1.9 2 0 0 2 2 2 1 Nematode insulin-related peptide beta type TPR_10 PF13374.1 EIW81335.1 - 0.025 14.4 0.2 0.45 10.5 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DPBB_1 PF03330.13 EIW81336.1 - 1.7e-08 34.3 0.3 1.2e-07 31.5 0.0 2.2 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIW81336.1 - 0.00032 20.3 0.6 0.00063 19.4 0.4 1.6 1 1 0 1 1 1 1 Barwin family SH3_9 PF14604.1 EIW81337.1 - 1.2e-22 79.1 0.9 9.5e-13 47.5 0.2 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EIW81337.1 - 2.4e-22 78.0 0.3 5.6e-10 38.4 0.2 2.5 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EIW81337.1 - 6.2e-21 73.6 0.0 3.9e-11 42.2 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 EIW81337.1 - 5e-15 55.4 0.0 5e-15 55.4 0.0 2.6 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain C1_1 PF00130.17 EIW81337.1 - 1.1e-09 37.8 3.8 1.8e-09 37.1 2.6 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_3 PF08239.6 EIW81337.1 - 0.00016 21.7 0.5 0.00052 20.1 0.0 2.0 2 0 0 2 2 2 1 Bacterial SH3 domain Tnp_DNA_bind PF14706.1 EIW81337.1 - 0.14 11.9 0.9 3.4 7.4 0.2 2.8 2 0 0 2 2 2 0 Transposase DNA-binding CAF1 PF04857.15 EIW81338.1 - 4.9e-67 226.0 0.0 7.4e-67 225.4 0.0 1.3 1 0 0 1 1 1 1 CAF1 family ribonuclease Fungal_trans PF04082.13 EIW81339.1 - 1.8e-17 63.0 0.3 3.3e-17 62.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW81339.1 - 0.00018 21.3 12.1 0.0003 20.6 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Carn_acyltransf PF00755.15 EIW81340.1 - 2.5e-167 557.5 0.0 2.9e-167 557.3 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Peptidase_C97 PF05903.9 EIW81341.1 - 3.2e-38 130.8 0.0 5.1e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 EIW81341.1 - 3.5e-16 58.7 0.0 7.8e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin PUL PF08324.6 EIW81341.1 - 1.5e-11 43.6 0.0 3.1e-11 42.5 0.0 1.5 1 1 0 1 1 1 1 PUL domain Thioredoxin_2 PF13098.1 EIW81341.1 - 1.6e-06 28.3 0.0 1.1e-05 25.5 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain T4_deiodinase PF00837.12 EIW81341.1 - 0.014 14.4 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 Iodothyronine deiodinase Redoxin PF08534.5 EIW81341.1 - 0.027 13.9 0.0 0.18 11.3 0.0 2.3 3 0 0 3 3 3 0 Redoxin Thioredoxin_8 PF13905.1 EIW81341.1 - 0.038 14.1 0.0 0.18 11.9 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin-like DSBA PF01323.15 EIW81341.1 - 0.12 11.8 0.0 1.1 8.7 0.0 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain AhpC-TSA PF00578.16 EIW81341.1 - 0.16 11.6 0.0 0.82 9.3 0.0 2.2 2 0 0 2 2 2 0 AhpC/TSA family Succ_DH_flav_C PF02910.15 EIW81342.1 - 0.00026 20.8 0.4 0.00065 19.5 0.1 1.8 2 0 0 2 2 2 1 Fumarate reductase flavoprotein C-term Bap31 PF05529.7 EIW81342.1 - 0.0087 15.5 1.0 0.022 14.2 0.7 1.7 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like IncA PF04156.9 EIW81342.1 - 0.11 12.0 12.1 0.62 9.6 2.3 2.6 2 1 0 2 2 2 0 IncA protein TBPIP PF07106.8 EIW81342.1 - 0.3 10.6 3.6 0.68 9.4 0.9 2.2 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DivIC PF04977.10 EIW81342.1 - 1.2 8.6 7.2 13 5.3 0.1 2.5 2 0 0 2 2 2 0 Septum formation initiator DUF4164 PF13747.1 EIW81342.1 - 3.2 7.9 10.3 2 8.6 1.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) Ctr PF04145.10 EIW81343.1 - 3.6e-28 98.4 0.0 4.4e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family GPI-anchored PF10342.4 EIW81344.1 - 4.2e-08 33.5 3.2 4.2e-08 33.5 2.2 2.6 1 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EIW81344.1 - 0.033 13.6 0.3 0.082 12.3 0.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) DUF3304 PF11745.3 EIW81344.1 - 0.094 12.9 0.0 0.26 11.5 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3304) DUF605 PF04652.11 EIW81344.1 - 0.1 11.9 10.2 0.12 11.7 7.1 1.1 1 0 0 1 1 1 0 Vta1 like Med3 PF11593.3 EIW81344.1 - 4 6.5 15.2 5.5 6.1 10.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal TPP_enzyme_N PF02776.13 EIW81345.1 - 1.7e-36 125.3 0.1 2.6e-36 124.7 0.1 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EIW81345.1 - 5.6e-21 74.7 0.0 1.7e-20 73.1 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EIW81345.1 - 5.6e-14 51.9 0.1 3.9e-13 49.2 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain PYRIN PF02758.11 EIW81345.1 - 0.045 13.4 0.2 0.097 12.3 0.1 1.5 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain OCC1 PF15506.1 EIW81345.1 - 0.17 11.8 0.5 0.69 9.8 0.1 2.2 2 0 0 2 2 2 0 OCC1 family Pkinase PF00069.20 EIW81346.1 - 6.6e-23 81.1 0.0 1e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW81346.1 - 3.9e-05 22.8 0.0 7e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW81346.1 - 0.0024 17.6 0.1 0.094 12.4 0.0 2.7 2 1 1 3 3 3 1 Phosphotransferase enzyme family Ribosomal_S19e PF01090.14 EIW81346.1 - 0.13 11.7 0.2 11 5.4 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein S19e FA_desaturase PF00487.19 EIW81347.1 - 4.8e-23 81.9 23.8 1.9e-22 79.9 16.5 1.8 1 1 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EIW81347.1 - 0.027 14.4 0.1 0.055 13.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) D123 PF07065.9 EIW81348.1 - 3.2e-79 266.1 0.0 3.7e-79 265.9 0.0 1.0 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 EIW81348.1 - 0.002 17.9 0.1 0.0035 17.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4343) Exo_endo_phos PF03372.18 EIW81349.1 - 1.7e-08 34.6 0.4 1.7e-08 34.6 0.2 1.8 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIW81349.1 - 8.7e-05 22.1 1.4 0.0077 15.8 0.1 3.6 3 1 0 3 3 3 1 Endonuclease-reverse transcriptase tRNA_anti-codon PF01336.20 EIW81349.1 - 0.08 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain zf-RING_2 PF13639.1 EIW81350.1 - 2.4e-07 30.4 7.5 2.4e-07 30.4 5.2 4.0 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EIW81350.1 - 1.5e-06 27.7 6.8 1.5e-06 27.7 4.7 4.7 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW81350.1 - 2.7e-06 27.0 7.0 2.7e-06 27.0 4.9 3.7 2 1 1 3 3 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIW81350.1 - 4.6e-06 26.5 7.8 4.6e-06 26.5 5.4 4.7 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 EIW81350.1 - 1.1e-05 25.2 10.8 1.1e-05 25.2 7.5 3.9 3 2 0 3 3 3 1 IBR domain zf-RING_UBOX PF13445.1 EIW81350.1 - 3e-05 23.6 1.6 3e-05 23.6 1.1 3.6 4 1 0 4 4 3 1 RING-type zinc-finger DUF904 PF06005.7 EIW81350.1 - 0.00037 20.7 2.9 0.00037 20.7 2.0 1.8 2 0 0 2 2 1 1 Protein of unknown function (DUF904) DivIC PF04977.10 EIW81350.1 - 0.00048 19.5 0.6 0.00048 19.5 0.4 1.6 2 0 0 2 2 2 1 Septum formation initiator bZIP_1 PF00170.16 EIW81350.1 - 0.00086 19.2 0.8 0.0018 18.1 0.5 1.5 1 0 0 1 1 1 1 bZIP transcription factor THOC7 PF05615.8 EIW81350.1 - 0.16 12.2 4.0 0.09 13.0 0.5 2.0 2 0 0 2 2 2 0 Tho complex subunit 7 IncA PF04156.9 EIW81350.1 - 0.16 11.5 6.3 0.93 9.0 1.3 2.2 2 0 0 2 2 2 0 IncA protein HAP1_N PF04849.8 EIW81350.1 - 1.1 8.1 6.7 0.078 11.9 0.3 1.9 2 0 0 2 2 2 0 HAP1 N-terminal conserved region DUF2968 PF11180.3 EIW81350.1 - 1.1 8.5 9.4 0.057 12.7 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) TMF_DNA_bd PF12329.3 EIW81350.1 - 2.1 8.1 9.0 0.36 10.6 2.3 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 EIW81350.1 - 5.1 6.9 7.7 0.6 9.9 1.9 1.8 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding VWA_2 PF13519.1 EIW81351.1 - 3e-14 53.5 0.3 1.2e-13 51.5 0.2 2.1 1 0 0 1 1 1 1 von Willebrand factor type A domain RHD3 PF05879.7 EIW81351.1 - 3e-08 32.1 0.2 7e-08 30.8 0.1 1.6 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EIW81351.1 - 1.7e-06 27.2 1.1 2.6e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain VWA PF00092.23 EIW81351.1 - 7.7e-05 22.4 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EIW81351.1 - 0.0063 16.3 0.0 0.047 13.5 0.0 2.2 2 0 0 2 2 2 1 vWA found in TerF C terminus RHD3 PF05879.7 EIW81353.1 - 6.6e-07 27.6 0.2 1.2e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EIW81353.1 - 3.5e-06 26.2 0.0 6.9e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain VWA_2 PF13519.1 EIW81354.1 - 2.3e-09 37.6 0.7 2.9e-09 37.2 0.5 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EIW81354.1 - 3.5e-07 30.1 0.0 5.1e-07 29.5 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EIW81354.1 - 0.00021 21.1 0.0 0.0003 20.6 0.0 1.1 1 0 0 1 1 1 1 vWA found in TerF C terminus Ribosomal_S19e PF01090.14 EIW81355.1 - 1.2e-54 183.5 0.0 1.4e-54 183.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e F-box-like PF12937.2 EIW81356.1 - 1.2e-05 24.9 0.3 1.2e-05 24.9 0.2 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIW81356.1 - 0.013 15.0 0.3 0.087 12.5 0.2 2.5 1 1 0 1 1 1 0 F-box domain Acetyltransf_3 PF13302.1 EIW81358.1 - 9.8e-22 77.6 0.0 1.3e-21 77.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIW81358.1 - 2.1e-14 53.7 0.0 2.5e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW81358.1 - 4.3e-13 49.0 0.0 6.8e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIW81358.1 - 1.2e-07 31.8 0.1 1.7e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIW81358.1 - 5.2e-07 29.6 0.0 7.1e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIW81358.1 - 3.5e-06 26.6 0.0 6.5e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein VWA_2 PF13519.1 EIW81359.1 - 6.3e-16 58.9 0.5 1.5e-15 57.7 0.2 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 EIW81359.1 - 1.2e-09 38.1 0.0 3.3e-09 36.7 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EIW81359.1 - 1.7e-05 24.7 0.0 0.00071 19.4 0.0 2.2 2 0 0 2 2 2 1 vWA found in TerF C terminus VWA_CoxE PF05762.9 EIW81359.1 - 0.00014 21.0 0.6 0.0014 17.7 0.2 2.1 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein RHD3 PF05879.7 EIW81360.1 - 1.5e-07 29.7 0.2 1.5e-07 29.7 0.1 2.8 2 1 0 2 2 2 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EIW81360.1 - 2.6e-06 26.6 0.0 4.9e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain zf-RING_2 PF13639.1 EIW81361.1 - 2.1e-07 30.6 7.6 2.1e-07 30.6 5.2 3.7 2 1 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EIW81361.1 - 1.9e-06 27.4 7.6 1.9e-06 27.4 5.3 3.7 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIW81361.1 - 5.4e-06 25.9 7.5 5.4e-06 25.9 5.2 3.7 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW81361.1 - 1.3e-05 25.1 8.4 1.3e-05 25.1 5.8 3.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIW81361.1 - 1.8e-05 24.3 1.5 1.8e-05 24.3 1.0 3.4 2 1 1 3 3 3 1 RING-type zinc-finger DUF4140 PF13600.1 EIW81361.1 - 0.16 12.4 1.4 0.35 11.3 1.0 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF904 PF06005.7 EIW81361.1 - 1 9.7 5.3 0.67 10.2 2.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF951 PF06107.6 EIW81361.1 - 6.6 6.3 7.0 1.3 8.5 0.1 3.0 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF951) Cep57_MT_bd PF06657.8 EIW81363.1 - 0.037 13.9 0.0 0.095 12.6 0.0 1.8 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF3253 PF11625.3 EIW81363.1 - 0.11 12.4 0.3 9.9 6.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) LppC PF04348.8 EIW81364.1 - 0.12 10.8 0.0 0.18 10.3 0.0 1.1 1 0 0 1 1 1 0 LppC putative lipoprotein COesterase PF00135.23 EIW81365.1 - 7.5e-84 282.3 3.5 8.4e-81 272.2 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW81365.1 - 9.9e-08 31.8 0.4 1.2e-06 28.2 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EIW81366.1 - 2.5e-91 307.0 2.0 1.6e-90 304.3 1.4 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW81366.1 - 9e-08 31.9 0.5 1.8e-06 27.6 0.2 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF4107 PF13389.1 EIW81366.1 - 0.21 11.2 0.3 0.4 10.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4107) DPM3 PF08285.6 EIW81370.1 - 0.057 13.2 1.5 0.21 11.4 1.0 2.0 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DAHP_synth_1 PF00793.15 EIW81371.1 - 1.1e-87 293.1 0.0 1.4e-87 292.8 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family zf-Tim10_DDP PF02953.10 EIW81372.1 - 1.1e-18 66.2 4.1 1.4e-18 65.9 2.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Mmp37 PF09139.6 EIW81372.1 - 0.091 11.7 0.0 0.091 11.7 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial matrix Mmp37 DUF842 PF05811.8 EIW81372.1 - 0.22 10.9 4.9 0.34 10.3 3.4 1.3 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) AhpC-TSA PF00578.16 EIW81373.1 - 3.9e-20 71.7 0.0 4.7e-20 71.5 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIW81373.1 - 6.8e-13 48.3 0.0 8e-13 48.1 0.0 1.0 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 EIW81373.1 - 0.004 17.2 0.0 0.0072 16.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Pacifastin_I PF05375.8 EIW81373.1 - 0.071 12.6 0.1 0.11 11.9 0.1 1.4 1 0 0 1 1 1 0 Pacifastin inhibitor (LCMII) Anthrax-tox_M PF09156.5 EIW81373.1 - 0.14 11.2 0.1 0.17 10.9 0.0 1.0 1 0 0 1 1 1 0 Anthrax toxin lethal factor, middle domain AhpC-TSA PF00578.16 EIW81374.1 - 8.3e-31 106.2 0.0 1.1e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIW81374.1 - 3.6e-20 72.0 0.0 5e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EIW81374.1 - 0.00018 21.3 0.1 0.00028 20.7 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Thioredoxin_8 PF13905.1 EIW81374.1 - 0.001 19.1 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like NMO PF03060.10 EIW81375.1 - 1.9e-64 217.9 0.1 2.6e-64 217.4 0.1 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EIW81375.1 - 1.1e-10 41.0 0.0 2e-05 23.6 0.4 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.12 EIW81375.1 - 0.012 14.7 0.1 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Thiamine monophosphate synthase/TENI FMN_dh PF01070.13 EIW81375.1 - 0.031 13.1 0.3 0.052 12.3 0.2 1.4 1 0 0 1 1 1 0 FMN-dependent dehydrogenase His_biosynth PF00977.16 EIW81375.1 - 0.062 12.5 0.2 0.12 11.6 0.1 1.4 1 0 0 1 1 1 0 Histidine biosynthesis protein NanE PF04131.9 EIW81375.1 - 0.083 11.8 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Glu_synthase PF01645.12 EIW81375.1 - 0.086 11.7 0.1 0.14 10.9 0.1 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase Acetyltransf_3 PF13302.1 EIW81376.1 - 4.5e-19 69.0 0.0 5.9e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIW81376.1 - 2.2e-14 53.6 0.0 2.8e-14 53.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW81376.1 - 3.1e-13 49.5 0.1 4.5e-13 49.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIW81376.1 - 0.0001 22.3 0.1 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIW81376.1 - 0.00014 21.7 0.0 0.00019 21.3 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIW81376.1 - 0.0002 21.0 0.0 0.00033 20.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EIW81376.1 - 0.099 12.7 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HET PF06985.6 EIW81377.1 - 4.6e-13 49.5 2.7 1.3e-10 41.5 0.0 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) ATP_synt_I PF03899.10 EIW81378.1 - 0.88 9.7 14.8 0.76 9.9 0.1 3.4 2 1 1 3 3 3 0 ATP synthase I chain UPF0197 PF05251.7 EIW81379.1 - 0.0075 16.5 1.7 0.0075 16.5 1.2 2.1 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0197) Acetyltransf_3 PF13302.1 EIW81380.1 - 2.2e-24 86.2 0.0 2.6e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIW81380.1 - 4.7e-14 52.6 0.0 5.3e-14 52.4 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW81380.1 - 6.5e-13 48.5 0.1 8.8e-13 48.0 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIW81380.1 - 4.7e-06 26.6 0.1 6.4e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIW81380.1 - 4.7e-05 23.3 0.0 8.6e-05 22.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIW81380.1 - 0.0012 18.5 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EIW81380.1 - 0.046 13.8 0.0 0.054 13.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIW81381.1 - 9.3e-20 71.2 0.0 1.2e-19 70.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW81381.1 - 3.1e-11 43.1 0.0 4.9e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EIW81381.1 - 2.7e-10 40.4 0.0 3.4e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIW81381.1 - 1.3e-05 25.3 0.0 1.9e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIW81381.1 - 0.0026 17.6 0.0 0.0035 17.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIW81381.1 - 0.0028 17.3 0.0 0.0058 16.3 0.0 1.5 1 1 0 1 1 1 1 FR47-like protein Sua5_yciO_yrdC PF01300.13 EIW81383.1 - 0.37 10.0 2.8 1.3 8.2 0.8 2.0 1 1 1 2 2 2 0 Telomere recombination Acetyltransf_3 PF13302.1 EIW81384.1 - 1.4e-18 67.4 0.0 4.5e-18 65.7 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW81384.1 - 6e-14 51.8 0.1 8.8e-14 51.3 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EIW81384.1 - 8.9e-10 38.7 0.0 3.9e-09 36.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIW81384.1 - 1.7e-05 24.7 0.2 0.00023 21.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIW81384.1 - 8.4e-05 22.6 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIW81384.1 - 0.013 15.2 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.1 EIW81384.1 - 0.029 14.4 0.0 0.061 13.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIW81385.1 - 5e-15 55.8 0.0 6.1e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW81385.1 - 2.4e-14 53.1 0.0 3.4e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EIW81385.1 - 7.6e-12 45.4 0.0 9.1e-12 45.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIW81385.1 - 1.4e-05 25.1 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIW81385.1 - 4.8e-05 23.2 0.0 6.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIW81385.1 - 0.0043 17.1 0.0 0.006 16.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIW81385.1 - 0.019 14.6 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Thaumatin PF00314.12 EIW81388.1 - 8.8e-65 218.1 14.4 1.2e-64 217.6 10.0 1.2 1 0 0 1 1 1 1 Thaumatin family DUF1664 PF07889.7 EIW81389.1 - 0.0024 17.6 0.7 0.17 11.6 0.0 3.4 2 1 2 4 4 4 1 Protein of unknown function (DUF1664) SF-assemblin PF06705.6 EIW81389.1 - 0.01 14.9 0.1 0.39 9.8 0.0 2.2 1 1 1 2 2 2 0 SF-assemblin/beta giardin MutS_III PF05192.13 EIW81389.1 - 0.011 15.5 0.2 0.042 13.6 0.2 1.8 2 0 0 2 2 2 0 MutS domain III Mst1_SARAH PF11629.3 EIW81389.1 - 0.054 13.3 5.8 0.48 10.2 0.8 2.5 2 0 0 2 2 2 0 C terminal SARAH domain of Mst1 Cortex-I_coil PF09304.5 EIW81389.1 - 2.1 8.4 7.1 19 5.3 0.7 2.8 1 1 1 2 2 2 0 Cortexillin I, coiled coil IncA PF04156.9 EIW81389.1 - 4.2 6.9 7.5 0.36 10.4 0.9 2.2 2 1 0 2 2 2 0 IncA protein DUF3852 PF12963.2 EIW81390.1 - 0.15 12.1 0.6 0.16 12.0 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3852) SseC PF04888.7 EIW81390.1 - 0.27 10.5 4.0 0.28 10.4 2.7 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family TrbL PF04610.9 EIW81390.1 - 0.48 10.0 3.5 0.82 9.3 2.4 1.5 1 1 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein DUF4179 PF13786.1 EIW81390.1 - 2.9 8.1 6.6 42 4.4 4.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) Peptidase_M3 PF01432.15 EIW81391.1 - 2.2e-06 27.0 0.0 2.5e-06 26.8 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M3 APH PF01636.18 EIW81392.1 - 1.2e-16 61.1 0.0 1.8e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIW81392.1 - 0.00025 20.6 0.0 0.00038 20.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EIW81392.1 - 0.2 10.7 0.0 0.27 10.3 0.0 1.1 1 0 0 1 1 1 0 Ecdysteroid kinase Peptidase_M3 PF01432.15 EIW81394.1 - 2.9e-108 362.8 0.0 3.7e-108 362.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Metal_resist PF13801.1 EIW81394.1 - 0.015 15.2 0.2 3.3 7.7 0.0 2.8 2 0 0 2 2 2 0 Heavy-metal resistance Peptidase_M50B PF13398.1 EIW81394.1 - 0.018 14.4 0.5 0.029 13.7 0.3 1.2 1 0 0 1 1 1 0 Peptidase M50B-like Peptidase_M91 PF14891.1 EIW81394.1 - 0.14 12.1 0.1 0.3 11.1 0.1 1.4 1 0 0 1 1 1 0 Effector protein 3Beta_HSD PF01073.14 EIW81395.1 - 2e-26 92.3 0.0 1.6e-25 89.3 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EIW81395.1 - 8.9e-18 64.1 0.0 1.9e-15 56.5 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Epimerase PF01370.16 EIW81395.1 - 1.5e-15 57.3 0.0 3.6e-15 56.0 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EIW81395.1 - 1.2e-07 31.7 0.0 4.5e-07 29.9 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EIW81395.1 - 1.2e-06 27.6 0.0 5.6e-06 25.4 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 EIW81395.1 - 0.0043 16.7 0.0 0.018 14.6 0.0 1.9 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EIW81395.1 - 0.033 14.1 0.0 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 EIW81395.1 - 0.18 10.7 0.0 0.45 9.3 0.0 1.6 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DUF1761 PF08570.5 EIW81396.1 - 3.7 7.5 15.6 27 4.8 5.9 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1761) DUF4131 PF13567.1 EIW81396.1 - 6.2 6.1 12.9 1.4 8.2 2.7 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) 3Beta_HSD PF01073.14 EIW81397.1 - 1.6e-63 214.0 0.0 6.2e-58 195.7 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EIW81397.1 - 3.4e-33 115.0 0.0 5.4e-33 114.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EIW81397.1 - 5e-15 55.1 0.0 6.9e-12 44.8 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EIW81397.1 - 2.5e-14 53.6 0.0 5.5e-14 52.5 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EIW81397.1 - 3.8e-13 48.9 0.1 5.3e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EIW81397.1 - 1.2e-05 24.3 0.1 9.2e-05 21.4 0.1 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EIW81397.1 - 0.029 13.6 0.0 0.22 10.7 0.0 2.1 1 1 0 1 1 1 0 NmrA-like family Nbl1_Borealin_N PF10444.4 EIW81398.1 - 3e-11 42.4 0.2 9e-11 40.9 0.3 1.6 2 0 0 2 2 2 1 Nbl1 / Borealin N terminal Mst1_SARAH PF11629.3 EIW81398.1 - 0.15 11.8 0.6 0.28 11.0 0.4 1.4 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 DUF2464 PF10240.4 EIW81398.1 - 0.97 8.7 6.7 1.9 7.7 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2464) POP1 PF06978.6 EIW81399.1 - 4.5e-46 156.8 17.4 4.9e-27 94.7 1.8 3.2 2 2 1 3 3 3 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EIW81399.1 - 1.3e-23 82.6 0.2 1.3e-23 82.6 0.1 2.3 3 0 0 3 3 3 1 POPLD (NUC188) domain GCV_T PF01571.16 EIW81399.1 - 0.00036 19.9 0.0 0.011 15.0 0.0 2.6 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EIW81399.1 - 0.056 13.4 0.2 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 Glycine cleavage T-protein C-terminal barrel domain MutS_III PF05192.13 EIW81400.1 - 0.0067 16.2 0.5 0.0093 15.7 0.3 1.2 1 0 0 1 1 1 1 MutS domain III IncA PF04156.9 EIW81400.1 - 0.017 14.7 0.1 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 IncA protein DUF479 PF04336.7 EIW81400.1 - 0.056 13.5 0.0 0.11 12.5 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function, DUF479 Spore_YpjB PF09577.5 EIW81400.1 - 0.066 12.7 0.0 0.083 12.4 0.0 1.1 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) Baculo_gp64 PF03273.8 EIW81400.1 - 0.069 11.3 0.3 0.093 10.8 0.2 1.2 1 0 0 1 1 1 0 Baculovirus gp64 envelope glycoprotein family Occludin_ELL PF07303.8 EIW81400.1 - 0.13 12.9 0.3 0.27 11.9 0.2 1.6 1 1 0 1 1 1 0 Occludin homology domain GAS PF13851.1 EIW81400.1 - 0.15 11.1 0.7 0.21 10.7 0.5 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding AAA_16 PF13191.1 EIW81402.1 - 1.1e-06 28.7 0.1 1.7e-06 28.1 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EIW81402.1 - 2e-05 24.3 0.1 3.5e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 NACHT domain APS_kinase PF01583.15 EIW81402.1 - 3.1e-05 23.6 0.1 4.8e-05 23.0 0.1 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.17 EIW81402.1 - 0.00017 21.7 0.0 0.00027 21.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 EIW81402.1 - 0.00034 20.7 0.0 0.0007 19.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW81402.1 - 0.00041 21.1 0.0 0.00072 20.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIW81402.1 - 0.0006 20.1 0.0 0.00095 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIW81402.1 - 0.00068 18.7 0.0 0.001 18.2 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin Arch_ATPase PF01637.13 EIW81402.1 - 0.0015 18.2 0.0 0.0016 18.1 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase DUF258 PF03193.11 EIW81402.1 - 0.0019 17.3 0.0 0.0026 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EIW81402.1 - 0.002 18.4 0.0 0.0036 17.6 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EIW81402.1 - 0.003 17.0 0.1 0.0053 16.2 0.1 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain PRK PF00485.13 EIW81402.1 - 0.0036 16.8 0.1 0.0044 16.6 0.1 1.3 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family DUF2075 PF09848.4 EIW81402.1 - 0.005 15.8 0.0 0.0059 15.6 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) MobB PF03205.9 EIW81402.1 - 0.0097 15.6 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activ_2 PF14532.1 EIW81402.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 EIW81402.1 - 0.015 14.1 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.10 EIW81402.1 - 0.019 14.6 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 NTPase Cytidylate_kin2 PF13189.1 EIW81402.1 - 0.021 14.7 0.0 0.033 14.0 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family UPF0079 PF02367.12 EIW81402.1 - 0.022 14.3 0.0 0.032 13.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 EIW81402.1 - 0.03 13.7 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 EIW81402.1 - 0.043 13.2 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.8 EIW81402.1 - 0.046 12.4 0.0 0.052 12.2 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus Torsin PF06309.6 EIW81402.1 - 0.047 13.5 0.0 0.072 12.9 0.0 1.4 1 1 0 1 1 1 0 Torsin CbiA PF01656.18 EIW81402.1 - 0.048 13.0 0.0 0.082 12.3 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF815 PF05673.8 EIW81402.1 - 0.056 12.3 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) KTI12 PF08433.5 EIW81402.1 - 0.071 12.3 0.0 0.096 11.8 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_31 PF13614.1 EIW81402.1 - 0.077 12.9 0.1 0.35 10.7 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_10 PF12846.2 EIW81402.1 - 0.081 12.3 0.0 0.092 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain ArgK PF03308.11 EIW81402.1 - 0.082 11.6 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 ArgK protein AAA_33 PF13671.1 EIW81402.1 - 0.083 12.7 0.1 0.22 11.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 EIW81402.1 - 0.084 11.8 0.0 0.088 11.7 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain PhoH PF02562.11 EIW81402.1 - 0.11 11.7 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein SMC_N PF02463.14 EIW81402.1 - 0.12 11.5 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EIW81402.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EIW81402.1 - 0.13 12.1 0.0 0.2 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain DAP3 PF10236.4 EIW81402.1 - 0.14 11.0 0.1 0.2 10.5 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 DUF566 PF04484.7 EIW81403.1 - 3.5 7.0 8.9 4.6 6.6 6.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF605 PF04652.11 EIW81403.1 - 4.8 6.4 13.2 5.3 6.3 9.1 1.1 1 0 0 1 1 1 0 Vta1 like Pkinase PF00069.20 EIW81404.1 - 5.9e-54 182.9 0.0 8.9e-54 182.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW81404.1 - 3.1e-26 91.9 0.0 1.3e-25 89.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1777 PF08648.7 EIW81404.1 - 5.2e-06 26.3 20.4 5.2e-06 26.3 14.1 3.0 2 1 0 2 2 2 1 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 EIW81404.1 - 0.00017 20.2 24.7 0.00025 19.6 17.1 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Kinase-like PF14531.1 EIW81404.1 - 0.00029 19.8 0.0 0.00065 18.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EIW81404.1 - 0.011 15.0 0.1 0.011 15.0 0.1 2.5 3 0 0 3 3 3 0 RIO1 family p450 PF00067.17 EIW81405.1 - 2.1e-46 158.4 0.0 2.7e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Retrotrans_gag PF03732.12 EIW81407.1 - 2.8e-10 40.1 1.8 2.8e-10 40.1 1.2 1.5 1 1 0 1 1 1 1 Retrotransposon gag protein HORMA PF02301.13 EIW81414.1 - 4.6e-35 121.0 0.1 5.2e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 HORMA domain ATG13 PF10033.4 EIW81414.1 - 0.0008 18.9 0.1 0.005 16.2 0.1 1.9 2 0 0 2 2 2 1 Autophagy-related protein 13 Peptidase_M1 PF01433.15 EIW81415.1 - 2e-55 188.5 0.0 2.7e-55 188.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EIW81415.1 - 5.9e-26 90.7 0.0 1.2e-25 89.7 0.0 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EIW81415.1 - 3.7e-13 49.6 0.1 8.1e-13 48.5 0.1 1.6 1 0 0 1 1 1 1 Peptidase MA superfamily Sporozoite_P67 PF05642.6 EIW81416.1 - 0.54 8.0 16.1 0.6 7.9 11.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Peptidase_S9 PF00326.16 EIW81417.1 - 3e-31 108.3 0.0 4.4e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EIW81417.1 - 1.2e-09 38.3 0.2 3.1e-09 37.0 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW81417.1 - 3.1e-09 36.7 0.3 1.3e-08 34.6 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EIW81417.1 - 2.3e-05 24.1 0.0 4.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EIW81417.1 - 7.5e-05 22.3 0.0 0.0035 16.9 0.0 2.6 3 0 0 3 3 3 1 alpha/beta hydrolase fold DLH PF01738.13 EIW81417.1 - 0.0077 15.5 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.15 EIW81417.1 - 0.0092 15.4 0.1 0.63 9.4 0.1 2.4 2 0 0 2 2 2 1 Putative esterase BAAT_C PF08840.6 EIW81417.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Proteasom_Rpn13 PF04683.8 EIW81418.1 - 3.8e-26 91.0 0.0 5.8e-26 90.4 0.0 1.3 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor DUF2205 PF10224.4 EIW81419.1 - 4.2e-12 45.4 0.2 5e-12 45.2 0.1 1.1 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 EIW81419.1 - 0.027 14.7 0.3 0.03 14.6 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF972) bZIP_1 PF00170.16 EIW81419.1 - 0.1 12.5 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 bZIP transcription factor ELF PF03317.8 EIW81421.1 - 0.45 9.7 4.3 0.7 9.1 3.0 1.3 1 0 0 1 1 1 0 ELF protein ECH PF00378.15 EIW81422.1 - 5e-74 248.5 1.9 5.7e-74 248.3 1.3 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EIW81422.1 - 0.0024 18.0 0.0 0.0062 16.6 0.0 1.7 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region Peptidase_S49 PF01343.13 EIW81422.1 - 0.025 14.3 0.3 0.62 9.8 0.0 2.3 2 0 0 2 2 2 0 Peptidase family S49 SDH_sah PF01972.11 EIW81422.1 - 0.14 10.9 0.1 0.26 10.0 0.1 1.5 1 0 0 1 1 1 0 Serine dehydrogenase proteinase SET PF00856.23 EIW81423.1 - 1.2e-08 35.3 0.0 2.7e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.13 EIW81423.1 - 1.1e-07 31.6 11.8 1.1e-07 31.6 8.2 2.1 2 1 0 2 2 2 1 MYND finger NDK PF00334.14 EIW81425.1 - 6.3e-05 22.7 0.0 0.00014 21.6 0.0 1.6 1 1 0 1 1 1 1 Nucleoside diphosphate kinase DER1 PF04511.10 EIW81426.1 - 1.3e-46 158.6 2.7 1.5e-46 158.3 1.8 1.0 1 0 0 1 1 1 1 Der1-like family Glyco_hydro_47 PF01532.15 EIW81427.1 - 2.5e-125 418.7 0.1 2.8e-125 418.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4419 PF14388.1 EIW81428.1 - 7.9e-97 324.0 0.0 9.6e-97 323.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) WWE PF02825.15 EIW81428.1 - 0.04 13.3 0.0 0.086 12.2 0.0 1.5 1 0 0 1 1 1 0 WWE domain Pardaxin PF07425.6 EIW81428.1 - 0.085 12.2 0.1 0.21 11.0 0.0 1.6 1 0 0 1 1 1 0 Pardaxin Mmp37 PF09139.6 EIW81430.1 - 1.7e-105 352.6 0.0 2.2e-105 352.3 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 FMO-like PF00743.14 EIW81431.1 - 6.6e-15 54.2 0.0 2.5e-13 49.0 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EIW81431.1 - 3.4e-13 50.1 0.1 8.8e-08 32.4 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW81431.1 - 2.1e-06 26.8 0.0 1.9e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 EIW81431.1 - 2.8e-06 27.4 0.0 9e-06 25.8 0.0 1.9 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 EIW81431.1 - 3e-06 27.2 0.0 0.0018 18.1 0.0 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW81431.1 - 0.00026 20.9 0.0 0.00076 19.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EIW81431.1 - 0.0013 17.3 0.1 0.31 9.4 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.14 EIW81431.1 - 0.0034 16.4 0.1 0.0077 15.3 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EIW81431.1 - 0.0046 16.7 0.4 0.74 9.5 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EIW81431.1 - 0.0095 16.1 0.1 0.14 12.4 0.1 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox PF00070.22 EIW81431.1 - 0.01 16.2 0.6 6.8 7.1 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW81431.1 - 0.013 14.4 0.2 1.8 7.3 0.0 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EIW81431.1 - 0.048 13.2 0.2 0.91 9.0 0.1 2.4 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain THF_DHG_CYH_C PF02882.14 EIW81431.1 - 0.08 12.0 0.2 1.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Alg6_Alg8 PF03155.10 EIW81432.1 - 3.2e-131 438.3 14.2 4e-106 355.6 2.9 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family 4HBT PF03061.17 EIW81433.1 - 8.3e-14 51.4 0.6 1.2e-13 50.9 0.4 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EIW81433.1 - 0.0019 17.9 0.0 0.0023 17.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.1 EIW81433.1 - 0.0093 15.9 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) REV PF00424.13 EIW81434.1 - 0.028 14.2 5.8 0.75 9.7 0.4 3.3 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) DUF3525 PF12039.3 EIW81434.1 - 0.29 9.6 11.1 0.34 9.3 0.1 3.9 2 1 3 5 5 5 0 Protein of unknown function (DUF3525) PepSY_TM_2 PF13703.1 EIW81435.1 - 1.3 9.1 7.5 0.15 12.2 0.6 2.5 2 0 0 2 2 2 0 PepSY-associated TM helix Pet127 PF08634.5 EIW81437.1 - 2.3e-98 328.7 0.0 3.7e-98 328.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 DUF4419 PF14388.1 EIW81438.1 - 2.4e-81 273.2 0.0 3e-81 272.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Glutaredoxin PF00462.19 EIW81441.1 - 0.051 13.5 0.0 0.19 11.7 0.0 2.0 1 1 1 2 2 2 0 Glutaredoxin Usp PF00582.21 EIW81443.1 - 4.5e-20 72.2 1.9 6.3e-20 71.7 0.0 2.2 2 0 0 2 2 2 1 Universal stress protein family MFS_1 PF07690.11 EIW81444.1 - 1.8e-14 53.2 36.6 2.6e-14 52.6 25.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EIW81444.1 - 4e-13 49.1 8.1 4e-13 49.1 5.6 2.7 2 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EIW81445.1 - 5e-17 61.6 32.0 5e-17 61.6 22.2 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EIW81445.1 - 1.1e-11 44.4 7.2 1.1e-11 44.4 5.0 2.2 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 Arf PF00025.16 EIW81446.1 - 7e-41 139.3 0.0 7.7e-41 139.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EIW81446.1 - 8.6e-18 64.2 0.0 9.8e-18 64.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW81446.1 - 7.9e-12 45.7 0.0 2.2e-11 44.2 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein SRPRB PF09439.5 EIW81446.1 - 2.6e-08 33.2 0.0 3e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EIW81446.1 - 1.3e-07 31.0 0.0 1.4e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EIW81446.1 - 2.1e-05 23.3 0.8 3e-05 22.9 0.1 1.5 2 0 0 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.18 EIW81446.1 - 7.1e-05 22.7 0.0 9.1e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIW81446.1 - 7.4e-05 22.2 0.0 0.00025 20.5 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EIW81446.1 - 0.011 15.5 0.3 0.52 10.1 0.5 2.1 1 1 1 2 2 2 0 Dynamin family ATP_bind_1 PF03029.12 EIW81446.1 - 0.015 14.8 0.1 1.5 8.3 0.0 2.1 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein Ndc80_HEC PF03801.8 EIW81448.1 - 0.12 11.8 0.2 0.23 10.8 0.2 1.5 1 0 0 1 1 1 0 HEC/Ndc80p family Cauli_VI PF01693.11 EIW81449.1 - 0.025 14.5 0.0 0.33 11.0 0.0 2.4 2 0 0 2 2 2 0 Caulimovirus viroplasmin zf-B_box PF00643.19 EIW81450.1 - 0.46 10.4 6.0 0.1 12.4 1.2 2.2 2 0 0 2 2 2 0 B-box zinc finger Thaumatin PF00314.12 EIW81452.1 - 1.2e-64 217.7 14.5 1.3e-64 217.5 10.1 1.0 1 0 0 1 1 1 1 Thaumatin family AAA_12 PF13087.1 EIW81453.1 - 1.1e-29 103.1 0.0 1.1e-27 96.7 0.0 2.4 1 1 1 2 2 2 2 AAA domain AAA_11 PF13086.1 EIW81453.1 - 8.2e-05 22.2 0.1 8.2e-05 22.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain DUF3525 PF12039.3 EIW81454.1 - 0.0075 14.8 8.0 1.7 7.0 0.1 4.2 2 1 3 5 5 5 3 Protein of unknown function (DUF3525) Pyr_redox_2 PF07992.9 EIW81455.1 - 2e-27 96.3 0.0 2.6e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW81455.1 - 2.3e-16 59.9 0.1 9.7e-14 51.5 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW81455.1 - 2e-07 31.2 0.1 0.00074 19.6 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW81455.1 - 1.7e-06 27.2 0.4 0.013 14.4 0.0 3.3 4 0 0 4 4 4 2 FAD dependent oxidoreductase Thi4 PF01946.12 EIW81455.1 - 3.7e-06 26.2 0.1 3.8e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 EIW81455.1 - 4.4e-05 22.5 4.3 0.0047 15.8 0.1 4.1 4 1 1 5 5 5 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EIW81455.1 - 6.3e-05 22.9 0.3 0.0016 18.4 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIW81455.1 - 0.00011 21.1 0.5 0.0025 16.7 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 EIW81455.1 - 0.00096 19.3 0.0 0.056 13.7 0.0 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EIW81455.1 - 0.0024 17.9 0.1 0.85 9.7 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 EIW81455.1 - 0.0042 16.2 0.1 0.051 12.6 0.1 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EIW81455.1 - 0.0062 15.6 0.3 0.053 12.5 0.0 2.2 2 1 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EIW81455.1 - 0.0076 14.7 0.4 0.046 12.1 0.1 2.3 3 0 0 3 3 3 1 HI0933-like protein K_oxygenase PF13434.1 EIW81455.1 - 0.0099 14.8 0.1 0.27 10.1 0.0 3.0 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EIW81455.1 - 0.012 15.4 0.2 4.6 6.9 0.0 2.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EIW81455.1 - 0.053 12.1 1.3 0.19 10.2 0.2 2.3 2 1 1 3 3 3 0 Tryptophan halogenase F420_oxidored PF03807.12 EIW81455.1 - 0.14 12.6 0.1 4.8 7.6 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF3816 PF12822.2 EIW81456.1 - 0.011 15.5 5.2 0.21 11.4 3.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) Form_Nir_trans PF01226.12 EIW81456.1 - 0.016 14.0 1.1 0.016 14.0 0.8 2.1 1 1 0 2 2 2 0 Formate/nitrite transporter WD40 PF00400.27 EIW81457.1 - 1.5e-05 24.6 0.0 0.00047 19.9 0.0 2.9 2 0 0 2 2 2 1 WD domain, G-beta repeat zf-DHHC PF01529.15 EIW81459.1 - 7 6.0 7.0 20 4.5 4.0 2.1 1 1 0 1 1 1 0 DHHC palmitoyltransferase GPI PF06560.6 EIW81460.1 - 0.087 11.8 0.0 0.17 10.8 0.0 1.5 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Ste5 PF11610.3 EIW81462.1 - 5.1 6.7 6.5 0.32 10.5 0.4 2.1 2 0 0 2 2 2 0 Scaffold protein Ste5-Fus5 binding region CgtA PF06306.6 EIW81463.1 - 0.037 13.2 0.0 0.054 12.7 0.0 1.1 1 0 0 1 1 1 0 Beta-1,4-N-acetylgalactosaminyltransferase (CgtA) F-box-like PF12937.2 EIW81465.1 - 3.7e-05 23.3 0.5 8.3e-05 22.2 0.3 1.6 1 0 0 1 1 1 1 F-box-like SET PF00856.23 EIW81467.1 - 1.3e-13 51.6 1.3 9.1e-13 48.8 0.9 2.1 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 EIW81467.1 - 5.7e-08 32.9 0.9 4e-07 30.2 0.0 2.2 2 0 0 2 2 2 1 Pre-SET motif TspO_MBR PF03073.10 EIW81468.1 - 0.035 13.6 0.8 0.13 11.7 0.0 2.2 2 1 0 2 2 2 0 TspO/MBR family Glyco_hydro_20 PF00728.17 EIW81469.1 - 6.2e-87 292.0 0.0 7.5e-87 291.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EIW81469.1 - 2.2e-12 47.7 0.0 4.4e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EIW81469.1 - 1.9e-09 38.1 0.0 3.7e-09 37.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 p450 PF00067.17 EIW81471.1 - 1.9e-67 227.7 0.0 2.9e-67 227.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF1488 PF07369.6 EIW81471.1 - 0.035 13.9 0.0 0.1 12.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) Peptidase_S32 PF05579.8 EIW81472.1 - 0.099 11.6 0.4 0.19 10.6 0.2 1.4 1 0 0 1 1 1 0 Equine arteritis virus serine endopeptidase S32 TMEM51 PF15345.1 EIW81477.1 - 0.067 12.8 0.0 0.089 12.4 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 DUF1232 PF06803.7 EIW81478.1 - 0.1 12.0 2.5 1.3 8.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1232) Mito_fiss_reg PF05308.6 EIW81478.1 - 1.1 8.5 4.4 1.2 8.4 3.1 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator TMEM154 PF15102.1 EIW81479.1 - 0.0074 15.9 0.1 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 TMEM154 protein family HemY_N PF07219.8 EIW81479.1 - 0.047 13.2 0.2 0.07 12.6 0.2 1.1 1 0 0 1 1 1 0 HemY protein N-terminus Hum_adeno_E3A PF05393.6 EIW81479.1 - 0.15 11.7 0.2 0.24 11.0 0.1 1.2 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Tetraspannin PF00335.15 EIW81481.1 - 1.4e-10 40.8 8.3 2e-10 40.3 5.8 1.2 1 0 0 1 1 1 1 Tetraspanin family Glyco_hydro_20 PF00728.17 EIW81488.1 - 1.5e-86 290.7 0.0 1.9e-86 290.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EIW81488.1 - 1.2e-11 45.3 0.0 2.3e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EIW81488.1 - 2.3e-07 31.3 0.2 4.5e-07 30.4 0.1 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Glyco_hydro_20 PF00728.17 EIW81489.1 - 8.6e-86 288.2 0.0 1e-85 287.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EIW81489.1 - 7.1e-12 46.1 0.0 1.3e-11 45.2 0.0 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EIW81489.1 - 8e-09 36.0 0.1 1.8e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Flagellin_IN PF07196.8 EIW81489.1 - 0.041 13.8 0.3 0.18 11.8 0.2 2.1 1 0 0 1 1 1 0 Flagellin hook IN motif DUF659 PF04937.10 EIW81490.1 - 7.4e-09 35.2 0.0 9e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) DUF772 PF05598.6 EIW81490.1 - 0.015 15.1 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 Transposase domain (DUF772) IL5 PF02025.10 EIW81490.1 - 0.096 12.7 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Interleukin 5 F-box-like PF12937.2 EIW81494.1 - 0.00023 20.8 0.4 0.0008 19.0 0.3 2.0 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIW81496.1 - 0.00035 20.2 0.9 0.0015 18.1 0.6 2.2 1 1 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIW81497.1 - 0.027 14.2 0.0 0.097 12.4 0.0 2.0 1 0 0 1 1 1 0 F-box-like ATP-synt_C PF00137.16 EIW81498.1 - 6e-30 102.9 28.4 2.2e-17 62.7 7.3 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Permease PF02405.11 EIW81498.1 - 0.0088 15.5 6.1 0.0088 15.5 4.2 2.1 1 1 1 2 2 2 1 Permease ABA_GPCR PF12430.3 EIW81498.1 - 0.35 9.9 1.7 11 5.1 0.1 2.1 1 1 0 2 2 2 0 Abscisic acid G-protein coupled receptor DUF2970 PF11174.3 EIW81498.1 - 0.77 9.3 6.8 0.56 9.8 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Sad1_UNC PF07738.8 EIW81499.1 - 1.8e-27 95.7 0.0 3.1e-27 95.0 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal PHD PF00628.24 EIW81500.1 - 0.00028 20.5 14.1 0.00094 18.8 3.8 2.9 3 0 0 3 3 3 2 PHD-finger zf-H2C2_2 PF13465.1 EIW81500.1 - 0.14 12.4 5.3 39 4.7 0.1 4.5 4 0 0 4 4 4 0 Zinc-finger double domain zf-Di19 PF05605.7 EIW81500.1 - 0.28 11.3 4.6 11 6.2 0.2 2.8 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding NADH-G_4Fe-4S_3 PF10588.4 EIW81500.1 - 0.49 9.6 2.8 0.3 10.3 0.2 1.9 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region MFS_1 PF07690.11 EIW81502.1 - 1.5e-33 116.0 41.2 4.8e-29 101.1 23.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily His_Phos_2 PF00328.17 EIW81503.1 - 1.5e-47 162.6 0.0 1.7e-47 162.4 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DUF3787 PF12655.2 EIW81503.1 - 0.17 11.6 0.6 0.36 10.5 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3787) COesterase PF00135.23 EIW81505.1 - 4.3e-105 352.4 0.0 1.6e-103 347.3 0.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EIW81505.1 - 2e-07 30.4 0.0 3.5e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EIW81505.1 - 1.2e-05 24.9 0.0 2.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Glyco_hydro_2 PF00703.16 EIW81506.1 - 1.5e-07 31.7 0.0 3.6e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EIW81506.1 - 2e-05 24.1 0.2 7.6e-05 22.3 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain COesterase PF00135.23 EIW81507.1 - 2.1e-90 303.9 0.0 5.3e-89 299.3 0.0 2.1 2 0 0 2 2 2 1 Carboxylesterase family Peptidase_S9 PF00326.16 EIW81507.1 - 0.00022 20.5 0.1 0.00038 19.7 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EIW81507.1 - 0.021 14.3 0.0 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW81507.1 - 0.063 13.0 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW81507.1 - 0.087 12.6 0.0 0.13 12.1 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family COesterase PF00135.23 EIW81508.1 - 5.1e-101 338.9 0.0 7.3e-100 335.1 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW81508.1 - 0.00016 21.3 0.0 0.0004 20.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIW81508.1 - 0.0054 15.9 0.4 0.011 14.9 0.3 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family F-box-like PF12937.2 EIW81509.1 - 2.8e-06 26.9 0.1 1.1e-05 25.1 0.0 2.1 2 0 0 2 2 2 1 F-box-like Copper-fist PF00649.13 EIW81510.1 - 0.16 11.2 0.4 0.16 11.2 0.3 2.9 3 0 0 3 3 3 0 Copper fist DNA binding domain Aldo_ket_red PF00248.16 EIW81512.1 - 3.2e-53 180.3 0.0 4e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Cauli_VI PF01693.11 EIW81515.1 - 3.9e-09 36.3 2.1 7.1e-09 35.5 0.6 1.9 1 1 1 2 2 2 1 Caulimovirus viroplasmin DUF3040 PF11239.3 EIW81516.1 - 0.016 15.2 0.0 0.045 13.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Pkinase PF00069.20 EIW81517.1 - 2e-46 158.2 0.0 1.6e-32 112.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW81517.1 - 2.1e-30 105.6 0.0 2.5e-23 82.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIW81517.1 - 0.0017 17.3 0.0 0.42 9.5 0.0 2.1 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EIW81517.1 - 0.0033 17.1 0.4 0.028 14.1 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIW81517.1 - 0.15 11.4 0.0 0.35 10.1 0.0 1.6 2 0 0 2 2 2 0 RIO1 family DUF3357 PF11837.3 EIW81518.1 - 0.097 12.5 0.1 7.8 6.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) SWI-SNF_Ssr4 PF08549.5 EIW81519.1 - 2.8e-08 32.5 16.5 4.4e-08 31.9 3.5 2.6 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1750) Sporozoite_P67 PF05642.6 EIW81519.1 - 0.6 7.9 12.0 0.71 7.6 8.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SlyX PF04102.7 EIW81519.1 - 0.69 10.3 9.8 0.19 12.1 4.1 2.0 2 0 0 2 2 2 0 SlyX PTR2 PF00854.16 EIW81520.1 - 6.8e-45 153.4 17.6 1.4e-43 149.1 12.2 2.7 1 1 0 1 1 1 1 POT family MTP18 PF10558.4 EIW81520.1 - 0.026 14.3 0.0 0.072 12.9 0.0 1.7 1 0 0 1 1 1 0 Mitochondrial 18 KDa protein (MTP18) MFS_1 PF07690.11 EIW81521.1 - 9e-26 90.4 42.5 9e-26 90.4 29.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EIW81522.1 - 7.4e-25 87.3 51.5 2.2e-22 79.2 28.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3733 PF12534.3 EIW81522.1 - 0.21 10.9 0.8 0.75 9.1 0.1 2.3 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 COesterase PF00135.23 EIW81523.1 - 1.9e-103 347.0 0.0 6.8e-103 345.1 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW81523.1 - 1.6e-05 24.6 0.0 4.9e-05 22.9 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIW81523.1 - 0.0057 15.8 0.1 0.0093 15.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family ERG4_ERG24 PF01222.12 EIW81524.1 - 0.0015 17.1 0.0 0.0015 17.1 0.0 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Glycos_transf_3 PF00591.16 EIW81525.1 - 1.5e-78 263.6 0.0 1.9e-78 263.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EIW81525.1 - 3.1e-10 39.4 0.0 7.8e-10 38.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain DUF3572 PF12096.3 EIW81525.1 - 0.09 12.6 0.0 0.36 10.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3572) HisG PF01634.13 EIW81526.1 - 1.5e-49 167.7 0.1 2.1e-49 167.2 0.1 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EIW81526.1 - 1.3e-25 89.0 0.0 2.7e-25 88.1 0.0 1.5 1 0 0 1 1 1 1 HisG, C-terminal domain NMT1 PF09084.6 EIW81526.1 - 0.00011 21.8 0.0 0.00016 21.3 0.0 1.2 1 0 0 1 1 1 1 NMT1/THI5 like Sec7_N PF12783.2 EIW81526.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.2 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal ICMT PF04140.9 EIW81527.1 - 2.8e-15 56.2 0.1 9.3e-15 54.6 0.1 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIW81527.1 - 1.5e-11 44.3 0.4 5.1e-11 42.6 0.3 2.0 1 1 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EIW81527.1 - 3.9e-07 28.9 0.0 5.3e-07 28.5 0.0 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.9 EIW81528.1 - 1e-13 51.2 0.2 2.2e-13 50.2 0.2 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIW81528.1 - 1e-12 48.0 0.7 1e-12 48.0 0.5 2.3 3 0 0 3 3 3 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EIW81528.1 - 1.5e-05 23.7 0.0 2.1e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Proteasome PF00227.21 EIW81530.1 - 8.7e-33 113.2 0.0 1.2e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Methyltransf_23 PF13489.1 EIW81531.1 - 1.3e-10 41.2 0.0 2.2e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW81531.1 - 5.5e-06 26.7 0.0 7.8e-05 23.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW81531.1 - 1.3e-05 24.8 0.0 0.00013 21.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW81531.1 - 1.7e-05 25.1 0.0 4.2e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW81531.1 - 2.2e-05 24.4 0.0 0.00094 19.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW81531.1 - 4.2e-05 22.7 0.1 0.0072 15.4 0.0 3.1 3 1 0 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EIW81531.1 - 0.00019 21.8 0.0 0.0023 18.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW81531.1 - 0.0034 17.9 0.1 0.11 13.0 0.1 2.9 1 1 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 EIW81531.1 - 0.015 14.8 0.0 0.66 9.4 0.0 2.2 2 0 0 2 2 2 0 DNA methylase GVQW PF13900.1 EIW81531.1 - 0.07 13.1 1.2 0.16 11.9 0.8 1.5 1 0 0 1 1 1 0 Putative binding domain Rot1 PF10681.4 EIW81532.1 - 4e-56 189.7 0.8 5e-56 189.4 0.6 1.0 1 0 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal Acetyltransf_7 PF13508.1 EIW81533.1 - 1.1e-09 38.3 0.0 1.5e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW81533.1 - 2.8e-09 36.8 0.0 3.7e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EIW81533.1 - 6.5e-07 29.4 0.0 7.7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIW81533.1 - 0.0011 19.1 0.0 0.0015 18.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 EIW81533.1 - 0.07 12.4 0.0 0.53 9.5 0.0 1.9 1 1 1 2 2 2 0 GNAT acetyltransferase 2 Acetyltransf_CG PF14542.1 EIW81533.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase UQ_con PF00179.21 EIW81534.1 - 3e-41 140.1 0.0 3.7e-41 139.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EIW81534.1 - 1.9e-15 56.1 0.9 1.9e-15 56.1 0.6 1.5 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain Prok-E2_B PF14461.1 EIW81534.1 - 0.0078 15.9 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B FeoA PF04023.9 EIW81534.1 - 0.11 12.4 0.1 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 FeoA domain Coprogen_oxidas PF01218.13 EIW81535.1 - 2e-108 361.4 0.0 2.7e-108 361.0 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase CsbD PF05532.7 EIW81536.1 - 6.2e-10 38.5 22.8 2.1e-08 33.7 6.1 3.1 2 1 1 3 3 3 3 CsbD-like MCLC PF05934.6 EIW81536.1 - 1.2 7.3 3.5 1.4 7.1 2.4 1.0 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Gly-zipper_OmpA PF13436.1 EIW81536.1 - 5.1 6.7 16.4 1 9.0 6.8 2.0 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain CsbD PF05532.7 EIW81537.1 - 1.5e-13 50.1 15.3 1.5e-08 34.1 2.0 2.2 1 1 1 2 2 2 2 CsbD-like HSP9_HSP12 PF04119.7 EIW81537.1 - 0.12 12.4 0.2 0.24 11.4 0.1 1.8 1 1 0 1 1 1 0 Heat shock protein 9/12 COesterase PF00135.23 EIW81539.1 - 2.1e-101 340.2 0.1 2.3e-100 336.8 0.0 1.9 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW81539.1 - 0.00051 19.6 0.2 0.007 15.9 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIW81539.1 - 0.0027 16.9 0.1 0.0041 16.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family F-box-like PF12937.2 EIW81540.1 - 0.00016 21.3 0.9 0.00048 19.7 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIW81540.1 - 0.0013 18.3 0.1 0.0032 17.0 0.1 1.7 1 0 0 1 1 1 1 F-box domain Clat_adaptor_s PF01217.15 EIW81541.1 - 4.4e-56 188.5 2.8 4.9e-56 188.4 2.0 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain UTP15_C PF09384.5 EIW81541.1 - 0.0072 16.0 0.3 1 9.0 0.0 2.1 1 1 0 2 2 2 2 UTP15 C terminal ArfGap PF01412.13 EIW81542.1 - 1.2e-33 115.3 0.5 1.2e-33 115.3 0.3 1.9 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf A2L_zn_ribbon PF08792.5 EIW81542.1 - 0.42 10.1 2.4 0.89 9.0 1.6 1.5 1 1 0 1 1 1 0 A2L zinc ribbon domain TPP_enzyme_N PF02776.13 EIW81543.1 - 1.2e-37 129.0 0.3 3.4e-37 127.5 0.2 1.9 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EIW81543.1 - 2e-12 47.0 0.1 8.2e-12 45.0 0.1 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EIW81543.1 - 5.7e-09 35.7 0.3 2.4e-08 33.6 0.2 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_N PF02776.13 EIW81544.1 - 8.7e-39 132.7 0.8 1.7e-38 131.8 0.2 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EIW81544.1 - 1.4e-06 28.0 0.0 2.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EIW81544.1 - 5.9e-06 25.9 0.1 3.2e-05 23.5 0.1 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain MFS_1 PF07690.11 EIW81546.1 - 5.8e-29 100.9 48.2 6.2e-25 87.6 27.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily RPAP1_C PF08620.5 EIW81547.1 - 1.1e-20 73.2 0.1 2.5e-20 72.0 0.0 1.7 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EIW81547.1 - 1.2e-07 31.1 0.5 2.3e-07 30.2 0.3 1.5 1 0 0 1 1 1 1 RPAP1-like, N-terminal Pmp3 PF01679.12 EIW81548.1 - 5.9e-20 70.7 8.5 7.6e-20 70.3 5.9 1.2 1 0 0 1 1 1 1 Proteolipid membrane potential modulator AAA PF00004.24 EIW81549.1 - 2e-84 280.3 0.0 8.2e-41 139.2 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIW81549.1 - 1.9e-11 43.8 0.0 9.2e-06 25.4 0.0 4.3 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EIW81549.1 - 2.9e-11 42.8 0.0 0.00075 18.6 0.0 3.3 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EIW81549.1 - 8.3e-11 42.2 1.1 3.3e-05 23.9 0.1 3.8 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EIW81549.1 - 2.9e-09 37.1 0.0 0.00053 20.1 0.0 4.2 2 2 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EIW81549.1 - 6.7e-08 32.5 0.0 0.00011 22.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EIW81549.1 - 1.5e-07 31.0 0.0 0.0002 20.8 0.0 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EIW81549.1 - 1.9e-07 30.7 2.9 6e-05 22.7 0.3 3.5 2 1 0 2 2 2 1 Part of AAA domain AAA_2 PF07724.9 EIW81549.1 - 2e-07 31.0 0.0 0.012 15.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 EIW81549.1 - 3.4e-07 29.3 0.0 0.0082 14.9 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus Zeta_toxin PF06414.7 EIW81549.1 - 6e-07 28.7 0.0 0.0005 19.2 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_25 PF13481.1 EIW81549.1 - 1.4e-06 27.8 0.8 0.15 11.4 0.1 3.7 2 1 1 3 3 3 2 AAA domain AAA_14 PF13173.1 EIW81549.1 - 2.5e-06 27.4 0.0 0.02 14.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EIW81549.1 - 1.2e-05 26.0 0.0 0.0016 19.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EIW81549.1 - 0.00014 21.8 0.0 0.018 15.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EIW81549.1 - 0.00016 20.9 0.2 0.24 10.5 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EIW81549.1 - 0.00027 21.0 0.0 0.081 13.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Sigma54_activ_2 PF14532.1 EIW81549.1 - 0.0012 18.8 0.0 0.59 10.1 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain NACHT PF05729.7 EIW81549.1 - 0.0022 17.6 0.0 0.13 11.9 0.0 3.1 3 0 0 3 3 3 1 NACHT domain DAP3 PF10236.4 EIW81549.1 - 0.0052 15.7 0.0 0.014 14.3 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_18 PF13238.1 EIW81549.1 - 0.0065 16.7 0.1 0.017 15.4 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_3 PF07726.6 EIW81549.1 - 0.0089 15.6 0.0 2.1 7.9 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EIW81549.1 - 0.01 15.1 0.1 0.25 10.5 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_11 PF13086.1 EIW81549.1 - 0.021 14.3 0.0 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EIW81549.1 - 0.021 14.5 0.0 8.4 6.0 0.0 3.4 2 2 2 4 4 4 0 Archaeal ATPase Sigma54_activat PF00158.21 EIW81549.1 - 0.025 14.0 0.0 0.96 8.9 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 EIW81549.1 - 0.034 13.7 0.1 6.2 6.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.11 EIW81549.1 - 0.035 12.9 0.0 0.4 9.4 0.0 2.2 2 0 0 2 2 2 0 AFG1-like ATPase UPF0079 PF02367.12 EIW81549.1 - 0.035 13.7 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Bac_DnaA PF00308.13 EIW81549.1 - 0.045 13.3 0.0 0.57 9.7 0.0 2.5 3 0 0 3 3 3 0 Bacterial dnaA protein Parvo_NS1 PF01057.12 EIW81549.1 - 0.06 12.2 0.0 0.22 10.3 0.0 1.8 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Rad17 PF03215.10 EIW81549.1 - 0.066 11.8 0.0 0.39 9.3 0.0 2.0 2 1 0 2 2 2 0 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 EIW81549.1 - 0.069 12.6 0.0 0.41 10.1 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATP-synt_ab PF00006.20 EIW81549.1 - 0.11 11.9 0.0 1.1 8.7 0.0 2.1 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain ResIII PF04851.10 EIW81549.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit NB-ARC PF00931.17 EIW81549.1 - 0.16 10.8 0.0 4.3 6.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain KaiC PF06745.8 EIW81549.1 - 0.23 10.5 0.0 7.8 5.5 0.0 2.3 2 0 0 2 2 2 0 KaiC AAA PF00004.24 EIW81550.1 - 1.3e-39 135.4 0.0 2.8e-39 134.3 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIW81550.1 - 6.1e-07 29.5 0.1 9.2e-05 22.4 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EIW81550.1 - 2.1e-06 26.9 0.0 4.4e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EIW81550.1 - 2.1e-06 27.8 0.1 4.5e-05 23.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EIW81550.1 - 2.3e-05 24.1 0.1 0.00026 20.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EIW81550.1 - 3.1e-05 23.8 0.0 6.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW81550.1 - 4.5e-05 24.2 0.0 0.00021 22.1 0.0 2.2 3 0 0 3 3 1 1 AAA domain AAA_33 PF13671.1 EIW81550.1 - 7.1e-05 22.7 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EIW81550.1 - 0.00022 21.1 0.0 0.00094 19.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.16 EIW81550.1 - 0.00038 19.6 0.1 0.0019 17.4 0.1 1.9 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EIW81550.1 - 0.00044 19.4 0.0 0.00076 18.6 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin IstB_IS21 PF01695.12 EIW81550.1 - 0.00084 18.7 0.1 0.0016 17.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.17 EIW81550.1 - 0.0014 18.8 0.0 0.0061 16.7 0.0 2.0 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.1 EIW81550.1 - 0.0014 18.9 0.0 0.0032 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EIW81550.1 - 0.002 18.1 0.0 0.0037 17.3 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 EIW81550.1 - 0.0023 17.3 0.2 0.11 11.8 0.1 2.4 1 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EIW81550.1 - 0.0028 17.3 0.0 0.011 15.4 0.0 1.9 1 1 1 2 2 2 1 NACHT domain AAA_28 PF13521.1 EIW81550.1 - 0.0028 17.6 0.0 0.0052 16.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EIW81550.1 - 0.003 17.1 0.0 0.0048 16.4 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 EIW81550.1 - 0.005 16.4 0.0 0.0082 15.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EIW81550.1 - 0.0076 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 EIW81550.1 - 0.0088 15.5 0.0 0.028 13.9 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain TIP49 PF06068.8 EIW81550.1 - 0.0089 14.7 0.1 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus Rad17 PF03215.10 EIW81550.1 - 0.011 14.4 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Arch_ATPase PF01637.13 EIW81550.1 - 0.028 14.1 0.0 0.13 11.8 0.0 1.9 1 1 1 2 2 2 0 Archaeal ATPase AAA_19 PF13245.1 EIW81550.1 - 0.039 13.7 0.3 0.14 11.9 0.1 1.9 2 0 0 2 2 2 0 Part of AAA domain Parvo_NS1 PF01057.12 EIW81550.1 - 0.044 12.6 0.0 0.064 12.1 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF815 PF05673.8 EIW81550.1 - 0.091 11.6 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 EIW81550.1 - 0.094 13.0 0.1 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter SKI PF01202.17 EIW81550.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase Bac_DnaA PF00308.13 EIW81550.1 - 0.13 11.8 0.0 0.54 9.8 0.0 1.8 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_3 PF07726.6 EIW81550.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EIW81550.1 - 0.2 10.4 0.0 0.38 9.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Glycos_transf_1 PF00534.15 EIW81552.1 - 6.7e-23 80.9 0.0 2e-22 79.4 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EIW81552.1 - 1.2e-07 31.9 0.1 3.8e-07 30.3 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Patatin PF01734.17 EIW81553.1 - 1.3e-10 41.5 0.1 3.3e-10 40.2 0.1 1.6 1 1 0 1 1 1 1 Patatin-like phospholipase DUF4333 PF14230.1 EIW81553.1 - 0.013 15.4 0.0 0.022 14.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4333) BTG PF07742.7 EIW81554.1 - 0.043 13.3 0.1 0.048 13.1 0.1 1.1 1 0 0 1 1 1 0 BTG family DIOX_N PF14226.1 EIW81555.1 - 3.1e-27 95.3 0.0 5.2e-27 94.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIW81555.1 - 3.9e-18 65.5 0.0 6.2e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Methyltransf_31 PF13847.1 EIW81556.1 - 2.1e-13 50.1 0.0 4.8e-13 48.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW81556.1 - 1.8e-12 47.8 0.1 5.2e-12 46.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW81556.1 - 1.3e-10 41.5 0.1 6.4e-10 39.3 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.8 EIW81556.1 - 1.4e-10 40.8 0.0 2.2e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EIW81556.1 - 1.4e-09 38.0 0.0 4.4e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW81556.1 - 2.4e-08 33.8 0.0 1.4e-07 31.4 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.9 EIW81556.1 - 3.6e-07 29.7 0.0 6.4e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EIW81556.1 - 3.5e-06 27.3 0.0 1.1e-05 25.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW81556.1 - 6.6e-06 26.5 0.1 5.5e-05 23.5 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Met_10 PF02475.11 EIW81556.1 - 0.00014 21.5 0.0 0.00023 20.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_24 PF13578.1 EIW81556.1 - 0.00079 20.2 0.0 0.0035 18.1 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EIW81556.1 - 0.00089 18.4 0.0 0.0015 17.7 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB CMAS PF02353.15 EIW81556.1 - 0.014 14.4 0.1 0.042 12.9 0.0 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 EIW81556.1 - 0.03 13.7 0.0 0.048 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Cons_hypoth95 PF03602.10 EIW81556.1 - 0.039 13.3 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 UPF0020 PF01170.13 EIW81556.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PRMT5 PF05185.11 EIW81556.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase Methyltransf_32 PF13679.1 EIW81556.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.6 2 0 0 2 2 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 EIW81556.1 - 0.13 10.9 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) RRM_1 PF00076.17 EIW81557.1 - 2.5e-08 33.4 0.1 7.3e-08 31.9 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EIW81557.1 - 9.8e-08 31.9 0.2 2.2e-07 30.8 0.1 1.5 1 0 0 1 1 1 1 PWI domain RRM_6 PF14259.1 EIW81557.1 - 7.6e-05 22.6 0.0 0.00016 21.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW81557.1 - 0.0016 18.2 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF494 PF04361.8 EIW81557.1 - 0.017 14.7 0.6 0.05 13.2 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF494) DUF814 PF05670.8 EIW81558.1 - 1.1e-22 79.7 0.0 2.5e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF814) Patatin PF01734.17 EIW81559.1 - 6.5e-44 150.3 7.8 1e-21 77.8 0.1 3.0 2 1 0 2 2 2 2 Patatin-like phospholipase AAA_22 PF13401.1 EIW81559.1 - 0.00076 19.6 0.0 0.0029 17.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EIW81559.1 - 0.0091 15.7 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_32 PF13654.1 EIW81559.1 - 0.07 11.7 0.0 0.4 9.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EIW81559.1 - 0.084 12.7 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EIW81559.1 - 0.13 11.9 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EIW81559.1 - 0.17 12.0 0.0 0.45 10.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase TPR_10 PF13374.1 EIW81560.1 - 6.9e-124 400.7 11.8 5e-13 48.4 0.0 10.5 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_12 PF13424.1 EIW81560.1 - 4.1e-106 347.0 27.3 9e-17 60.7 0.1 7.8 1 1 7 9 9 9 9 Tetratricopeptide repeat TPR_7 PF13176.1 EIW81560.1 - 1e-29 99.9 14.0 0.034 13.9 0.0 10.6 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.1 EIW81560.1 - 3.9e-24 84.0 8.5 0.00016 21.2 0.0 6.8 4 2 4 8 8 7 7 TPR repeat TPR_16 PF13432.1 EIW81560.1 - 1.1e-23 83.2 0.8 0.0036 17.9 0.0 8.1 1 1 9 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.23 EIW81560.1 - 2.5e-22 77.4 23.5 0.44 10.2 0.0 11.0 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_17 PF13431.1 EIW81560.1 - 5.3e-20 69.8 12.7 0.14 12.3 0.0 10.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIW81560.1 - 2.9e-14 51.6 23.5 0.72 9.7 0.0 10.4 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIW81560.1 - 1.8e-13 49.3 12.9 2.2 8.4 0.0 10.6 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIW81560.1 - 5.4e-10 39.4 23.9 3.4 8.0 0.3 10.3 1 1 10 11 11 11 1 Tetratricopeptide repeat DUF814 PF05670.8 EIW81560.1 - 4.4e-08 32.9 3.4 8 6.4 0.0 7.1 3 3 4 7 7 7 0 Domain of unknown function (DUF814) TPR_4 PF07721.9 EIW81560.1 - 7.4e-08 32.1 0.1 3.8 8.2 0.0 8.2 9 0 0 9 9 9 1 Tetratricopeptide repeat PPR PF01535.15 EIW81560.1 - 1.7e-06 27.5 4.5 20 5.4 0.0 8.9 10 0 0 10 10 9 0 PPR repeat CPSase_L_chain PF00289.17 EIW81560.1 - 5.3e-05 23.2 2.7 13 5.9 0.0 7.0 3 3 6 9 9 9 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Rapsyn_N PF10579.4 EIW81560.1 - 0.00012 21.7 3.6 1.4 8.7 0.0 5.7 3 3 4 7 7 7 1 Rapsyn N-terminal myristoylation and linker region DUF3157 PF11355.3 EIW81560.1 - 0.00034 19.9 2.5 1.9 7.7 0.0 4.1 3 2 3 6 6 6 2 Protein of unknown function (DUF3157) DUF4074 PF13293.1 EIW81560.1 - 0.0093 16.1 13.0 7.9 6.7 0.1 6.6 7 2 1 8 8 7 0 Domain of unknown function (DUF4074) SSI PF00720.12 EIW81560.1 - 0.01 15.7 1.1 4.4 7.3 0.0 4.4 1 1 7 8 8 8 0 Subtilisin inhibitor-like Porin_O_P PF07396.6 EIW81560.1 - 0.015 14.1 0.0 0.43 9.3 0.0 2.5 1 1 3 4 4 4 0 Phosphate-selective porin O and P DUF1697 PF08002.6 EIW81560.1 - 0.024 14.6 2.2 3.7 7.5 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF1697) DUF59 PF01883.14 EIW81560.1 - 0.038 13.9 0.1 38 4.3 0.0 4.8 5 0 0 5 5 5 0 Domain of unknown function DUF59 Lactate_perm PF02652.9 EIW81560.1 - 0.16 10.4 0.1 25 3.2 0.0 3.7 3 1 2 5 5 5 0 L-lactate permease DUF642 PF04862.7 EIW81560.1 - 0.22 11.1 3.6 31 4.1 0.2 5.1 4 2 3 7 7 7 0 Protein of unknown function (DUF642) TPR_3 PF07720.7 EIW81560.1 - 1.6 8.5 13.3 99 2.8 0.0 7.4 9 0 0 9 9 9 0 Tetratricopeptide repeat HIT PF01230.18 EIW81561.1 - 3.9e-24 85.0 0.3 5.4e-24 84.5 0.2 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EIW81561.1 - 1.8e-11 44.3 0.2 2.4e-11 43.8 0.1 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EIW81561.1 - 5e-06 26.1 0.1 7.8e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 DUF1161 PF06649.7 EIW81561.1 - 0.054 13.4 0.1 0.38 10.6 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF1161) GSH_synth_ATP PF03917.12 EIW81562.1 - 6e-94 314.6 0.0 1.3e-58 198.4 0.0 2.0 2 0 0 2 2 2 2 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EIW81562.1 - 6.5e-35 119.4 0.0 1.1e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic glutathione synthase FMN_dh PF01070.13 EIW81563.1 - 6.7e-111 370.5 0.2 8.3e-111 370.2 0.2 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase ThiG PF05690.9 EIW81563.1 - 8e-08 31.6 0.0 0.032 13.2 0.0 3.4 3 0 0 3 3 3 3 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 EIW81563.1 - 0.005 15.7 0.4 0.018 13.9 0.0 2.0 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain COesterase PF00135.23 EIW81564.1 - 3.6e-102 342.8 0.0 1.8e-101 340.5 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW81564.1 - 0.00038 20.0 0.6 0.0017 17.9 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold zf-C2H2_4 PF13894.1 EIW81565.1 - 3e-07 30.3 7.5 0.0023 18.1 0.5 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIW81565.1 - 8.5e-07 28.9 13.2 0.0016 18.6 1.7 3.3 2 1 1 3 3 3 2 Zinc finger, C2H2 type FpoO PF10621.4 EIW81565.1 - 0.074 13.1 0.3 0.12 12.4 0.2 1.4 1 0 0 1 1 1 0 F420H2 dehydrogenase subunit FpoO DUF2175 PF09943.4 EIW81565.1 - 0.14 12.1 0.5 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) zf-Di19 PF05605.7 EIW81565.1 - 0.19 11.8 5.3 2 8.5 0.6 2.8 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Ogr_Delta PF04606.7 EIW81565.1 - 0.76 9.4 5.6 3.3 7.4 0.0 3.3 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger OrfB_Zn_ribbon PF07282.6 EIW81565.1 - 1.2 8.8 8.3 4.4 7.0 1.8 2.9 2 1 2 4 4 4 0 Putative transposase DNA-binding domain Zn-ribbon_8 PF09723.5 EIW81565.1 - 2.1 8.3 12.2 1.2 9.1 0.8 3.3 2 1 1 3 3 3 0 Zinc ribbon domain GH3 PF03321.8 EIW81566.1 - 8.9e-35 120.1 0.0 2.5e-23 82.4 0.0 2.0 1 1 1 2 2 2 2 GH3 auxin-responsive promoter Penicil_amidase PF01804.13 EIW81566.1 - 0.012 14.7 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 Penicillin amidase GH3 PF03321.8 EIW81567.1 - 1.8e-39 135.6 0.0 2.2e-39 135.4 0.0 1.1 1 0 0 1 1 1 1 GH3 auxin-responsive promoter DUF2281 PF10047.4 EIW81567.1 - 0.14 12.4 0.1 0.4 11.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) GH3 PF03321.8 EIW81568.1 - 4.8e-35 121.0 0.0 6.3e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 GH3 auxin-responsive promoter Abi PF02517.11 EIW81569.1 - 5.7e-13 48.8 8.4 1.1e-12 47.8 5.1 2.0 1 1 1 2 2 2 1 CAAX protease self-immunity GH3 PF03321.8 EIW81570.1 - 4.9e-40 137.5 0.0 6.9e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 GH3 auxin-responsive promoter DUF423 PF04241.10 EIW81571.1 - 0.019 14.8 0.8 0.077 12.9 0.6 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF423) Amastin PF07344.6 EIW81571.1 - 0.23 11.0 10.4 1.1 8.8 5.0 2.7 2 1 0 2 2 2 0 Amastin surface glycoprotein DUF2628 PF10947.3 EIW81571.1 - 0.92 9.3 8.4 2.5 7.9 1.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2628) Phage_holin_2 PF04550.7 EIW81572.1 - 1.6 8.8 6.3 0.85 9.7 1.6 2.3 2 1 0 2 2 2 0 Phage holin family 2 GH3 PF03321.8 EIW81574.1 - 1.5e-43 149.1 0.0 2.6e-37 128.5 0.0 2.0 2 0 0 2 2 2 2 GH3 auxin-responsive promoter GH3 PF03321.8 EIW81575.1 - 9.6e-38 129.9 0.0 1.3e-37 129.5 0.0 1.0 1 0 0 1 1 1 1 GH3 auxin-responsive promoter zf-C2H2_4 PF13894.1 EIW81576.1 - 1.7e-08 34.1 4.0 0.0025 18.0 0.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIW81576.1 - 1.1e-06 28.6 10.8 0.0027 17.9 1.0 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type Ogr_Delta PF04606.7 EIW81576.1 - 0.037 13.6 5.6 0.088 12.4 0.0 3.0 3 0 0 3 3 3 0 Ogr/Delta-like zinc finger DUF2175 PF09943.4 EIW81576.1 - 0.15 12.1 1.3 1.3 9.1 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) Zn-ribbon_8 PF09723.5 EIW81576.1 - 1.6 8.7 10.2 4.5 7.3 1.1 3.2 2 1 1 3 3 3 0 Zinc ribbon domain OrfB_Zn_ribbon PF07282.6 EIW81576.1 - 1.8 8.2 6.3 9.7 5.9 0.1 3.3 2 1 2 4 4 4 0 Putative transposase DNA-binding domain zf-TRAF PF02176.13 EIW81576.1 - 1.8 8.9 8.9 0.74 10.2 0.4 2.9 2 1 1 3 3 3 0 TRAF-type zinc finger IBR PF01485.16 EIW81576.1 - 4.5 7.2 10.6 20 5.1 5.8 2.7 2 1 0 2 2 2 0 IBR domain zf-MIZ PF02891.15 EIW81576.1 - 7.2 6.2 8.9 2.2 7.8 1.7 3.1 4 1 0 4 4 4 0 MIZ/SP-RING zinc finger F-box PF00646.28 EIW81577.1 - 0.022 14.4 0.3 0.063 12.9 0.2 1.8 1 0 0 1 1 1 0 F-box domain adh_short PF00106.20 EIW81579.1 - 4.9e-20 72.1 0.1 6.3e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW81579.1 - 1.3e-06 28.2 0.0 1.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW81579.1 - 0.00015 21.3 0.1 0.00024 20.5 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW81579.1 - 0.0093 15.9 0.1 0.021 14.8 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding Hydrolase_6 PF13344.1 EIW81579.1 - 0.021 14.7 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase N_NLPC_P60 PF12912.2 EIW81582.1 - 0.12 12.5 0.3 0.16 12.0 0.1 1.4 1 1 0 1 1 1 0 NLPC_P60 stabilising domain, N term F-box-like PF12937.2 EIW81583.1 - 0.025 14.3 0.3 0.06 13.0 0.2 1.7 1 0 0 1 1 1 0 F-box-like EB1 PF03271.12 EIW81584.1 - 1.3e-15 57.1 2.0 2.5e-15 56.2 1.4 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif CH PF00307.26 EIW81584.1 - 1.4e-06 28.2 1.0 2.5e-06 27.4 0.7 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain Suppressor_APC PF11414.3 EIW81584.1 - 0.02 14.6 0.5 0.05 13.3 0.4 1.7 1 1 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein DUF3702 PF12486.3 EIW81584.1 - 0.11 12.1 0.2 10 5.7 0.2 2.2 1 1 1 2 2 2 0 ImpA domain protein Matrilin_ccoil PF10393.4 EIW81584.1 - 0.17 11.2 0.9 0.28 10.5 0.1 1.7 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin MFS_1 PF07690.11 EIW81585.1 - 3.1e-26 91.9 54.8 1.8e-18 66.4 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3311 PF11755.3 EIW81585.1 - 0.011 15.2 1.4 0.043 13.3 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) GFA PF04828.9 EIW81588.1 - 1.2e-23 82.8 0.5 1.7e-23 82.3 0.4 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme GFA PF04828.9 EIW81589.1 - 2.2e-24 85.2 0.4 3e-24 84.7 0.3 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 EIW81589.1 - 7.6 6.1 7.5 1.5 8.4 0.9 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain GFA PF04828.9 EIW81590.1 - 8.8e-26 89.6 3.2 1.3e-25 89.1 2.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme SEF14_adhesin PF06443.6 EIW81590.1 - 0.093 12.3 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 SEF14-like adhesin FYVE PF01363.16 EIW81590.1 - 5.6 6.9 8.1 4 7.4 3.9 2.1 1 1 1 2 2 2 0 FYVE zinc finger Hexapep PF00132.19 EIW81591.1 - 4.4e-06 25.9 13.1 0.005 16.3 0.1 4.3 2 2 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Subtilosin_A PF11420.3 EIW81591.1 - 0.19 11.7 3.3 0.68 10.0 0.1 2.6 2 1 0 2 2 2 0 Bacteriocin subtilosin A Hexapep_2 PF14602.1 EIW81591.1 - 0.76 9.3 11.5 0.9 9.1 2.3 3.2 3 1 0 3 3 3 0 Hexapeptide repeat of succinyl-transferase SspK PF08176.7 EIW81592.1 - 0.091 12.7 0.1 0.21 11.6 0.1 1.5 1 0 0 1 1 1 0 Small acid-soluble spore protein K family Calpain_inhib PF00748.14 EIW81592.1 - 0.5 10.7 6.0 0.16 12.3 1.7 1.9 1 1 1 2 2 2 0 Calpain inhibitor dsrm PF00035.20 EIW81594.1 - 0.0002 21.8 0.0 0.00031 21.2 0.0 1.5 1 1 0 1 1 1 1 Double-stranded RNA binding motif Peptidase_M20 PF01546.23 EIW81595.1 - 8.2e-33 113.5 0.0 1e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EIW81595.1 - 3.4e-16 58.9 0.0 6.4e-16 58.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain adh_short PF00106.20 EIW81596.1 - 9.4e-16 58.1 0.0 1.3e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW81596.1 - 0.00069 19.3 0.0 0.00099 18.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Sigma54_activ_2 PF14532.1 EIW81596.1 - 0.052 13.5 0.0 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain GH3 PF03321.8 EIW81597.1 - 5.9e-30 104.2 0.0 4.8e-17 61.6 0.0 3.0 3 0 0 3 3 3 3 GH3 auxin-responsive promoter zf-C2H2_4 PF13894.1 EIW81598.1 - 4.3e-08 32.9 8.1 0.00046 20.3 1.4 3.1 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIW81598.1 - 3.2e-07 30.3 12.4 0.001 19.2 1.7 3.3 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn-ribbon_8 PF09723.5 EIW81598.1 - 0.21 11.5 11.5 0.5 10.3 1.7 3.3 2 1 1 3 3 3 0 Zinc ribbon domain Rubredoxin PF00301.15 EIW81598.1 - 0.41 10.5 3.0 1 9.2 0.0 2.8 3 0 0 3 3 3 0 Rubredoxin zf-MIZ PF02891.15 EIW81598.1 - 1.4 8.5 5.8 0.31 10.5 0.2 2.6 4 0 0 4 4 4 0 MIZ/SP-RING zinc finger SprT-like PF10263.4 EIW81598.1 - 1.7 8.2 7.5 10 5.7 5.2 2.0 1 1 0 1 1 1 0 SprT-like family zf-TRAF PF02176.13 EIW81598.1 - 1.9 8.9 7.4 4.5 7.7 0.2 2.6 2 1 1 3 3 3 0 TRAF-type zinc finger zf-H2C2_2 PF13465.1 EIW81598.1 - 2 8.8 10.0 3.3 8.1 0.1 3.0 3 0 0 3 3 3 0 Zinc-finger double domain zf-Di19 PF05605.7 EIW81598.1 - 2.2 8.4 7.0 2.6 8.2 0.5 2.8 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.16 EIW81598.1 - 3.9 7.4 9.1 51 3.8 6.3 2.2 1 1 0 1 1 1 0 IBR domain dsrm PF00035.20 EIW81599.1 - 2.4e-06 28.0 0.0 2.6e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif Acetyltransf_1 PF00583.19 EIW81599.1 - 0.064 13.2 0.1 0.074 13.0 0.1 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family REV PF00424.13 EIW81600.1 - 0.14 12.0 7.4 5.2 7.0 2.1 3.3 3 0 0 3 3 3 0 REV protein (anti-repression trans-activator protein) RseA_C PF03873.8 EIW81600.1 - 1.5 8.7 5.1 1 9.2 0.1 3.1 3 0 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain WD40 PF00400.27 EIW81604.1 - 1.2e-08 34.4 11.5 0.0055 16.5 0.4 5.7 5 1 0 5 5 5 2 WD domain, G-beta repeat DUF3418 PF11898.3 EIW81604.1 - 0.36 9.1 0.1 0.51 8.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) C1_3 PF07649.7 EIW81604.1 - 1 9.4 12.1 0.11 12.5 4.7 2.1 2 0 0 2 2 2 0 C1-like domain F-box-like PF12937.2 EIW81609.1 - 1.5e-07 31.0 0.6 4.5e-07 29.4 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW81609.1 - 4.8e-07 29.2 2.6 7.3e-07 28.6 0.2 2.3 2 0 0 2 2 2 1 F-box domain NACHT PF05729.7 EIW81610.1 - 7e-11 42.0 0.7 2.6e-10 40.2 0.1 2.2 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EIW81610.1 - 0.0005 20.1 1.0 0.0024 17.9 0.7 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW81610.1 - 0.0012 18.9 0.0 0.017 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EIW81610.1 - 0.0037 16.9 0.0 0.031 13.9 0.0 2.4 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EIW81610.1 - 0.08 12.6 0.0 0.2 11.3 0.0 1.9 2 1 0 2 2 2 0 Archaeal ATPase NACHT PF05729.7 EIW81611.1 - 4.8e-05 23.0 0.0 6.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW81611.1 - 0.00011 22.3 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EIW81611.1 - 0.0054 16.4 0.0 0.0062 16.2 0.0 1.1 1 0 0 1 1 1 1 Archaeal ATPase MobB PF03205.9 EIW81611.1 - 0.0079 15.9 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EIW81611.1 - 0.014 15.5 0.0 0.022 14.8 0.0 1.4 1 1 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EIW81611.1 - 0.093 12.3 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 TrwB_AAD_bind PF10412.4 EIW81611.1 - 0.1 11.2 0.0 0.2 10.2 0.0 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain SRPRB PF09439.5 EIW81611.1 - 0.1 11.7 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit T2SE PF00437.15 EIW81611.1 - 0.11 11.4 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 EIW81612.1 - 0.024 14.3 0.0 0.051 13.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain GH3 PF03321.8 EIW81613.1 - 1.1e-28 100.1 0.0 3.5e-15 55.5 0.0 3.1 3 0 0 3 3 3 3 GH3 auxin-responsive promoter 3-alpha PF03475.9 EIW81613.1 - 0.033 13.8 0.1 0.078 12.7 0.1 1.6 1 0 0 1 1 1 0 3-alpha domain Flu_NS2 PF00601.14 EIW81619.1 - 0.067 13.4 0.2 3.1 8.0 0.0 2.2 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) Terpene_synth_C PF03936.11 EIW81622.1 - 2.4e-05 23.6 0.0 2.7e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.6 EIW81622.1 - 0.11 11.1 0.6 0.2 10.2 0.2 1.7 2 1 0 2 2 2 0 Trichodiene synthase (TRI5) dsrm PF00035.20 EIW81624.1 - 6.1e-08 33.1 0.0 1.2e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif dsrm PF00035.20 EIW81625.1 - 2.7e-07 31.0 0.0 5.3e-07 30.1 0.0 1.4 2 0 0 2 2 2 1 Double-stranded RNA binding motif F-box-like PF12937.2 EIW81626.1 - 7.8e-07 28.7 0.6 1.7e-06 27.6 0.4 1.6 1 0 0 1 1 1 1 F-box-like Ste50p-SAM PF09235.5 EIW81626.1 - 0.0084 16.1 0.2 0.23 11.4 0.1 2.3 2 0 0 2 2 2 1 Ste50p, sterile alpha motif LRR_8 PF13855.1 EIW81626.1 - 0.0097 15.6 0.3 0.23 11.2 0.0 3.0 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.2 EIW81627.1 - 2.7 7.7 6.3 29 4.4 0.0 5.0 6 1 0 6 6 6 0 Leucine Rich repeats (2 copies) LRR_4 PF12799.2 EIW81628.1 - 0.15 11.6 2.2 10 5.8 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Chitin_synth_1 PF01644.12 EIW81631.1 - 3.2e-86 287.1 0.1 5.2e-86 286.4 0.1 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EIW81631.1 - 1.4e-31 108.0 0.1 2.7e-31 107.0 0.1 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EIW81631.1 - 5.9e-24 84.3 0.5 9.4e-18 63.8 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EIW81631.1 - 4.6e-05 23.3 0.0 0.00015 21.6 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EIW81631.1 - 0.0011 18.6 15.4 0.023 14.4 10.7 2.6 1 1 0 1 1 1 1 Glycosyl transferase family group 2 dsrm PF00035.20 EIW81632.1 - 1.5e-08 35.0 0.1 3.1e-08 34.0 0.0 1.5 2 0 0 2 2 2 1 Double-stranded RNA binding motif GST_N_3 PF13417.1 EIW81633.1 - 7.1e-10 38.9 0.0 1.5e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW81633.1 - 2.5e-06 27.2 0.1 5.2e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW81633.1 - 7.9e-06 25.7 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW81633.1 - 8.3e-05 22.6 0.0 0.0002 21.4 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW81633.1 - 0.035 14.0 0.0 0.085 12.8 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DSPc PF00782.15 EIW81634.1 - 2.6e-31 107.9 0.0 3.4e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EIW81634.1 - 0.00033 19.6 0.0 0.00041 19.3 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Y_phosphatase PF00102.22 EIW81634.1 - 0.013 14.8 0.0 0.019 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EIW81634.1 - 0.085 12.8 0.0 0.12 12.4 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Myotub-related PF06602.9 EIW81634.1 - 0.12 11.0 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain Asp PF00026.18 EIW81636.1 - 2.1e-37 129.0 0.0 3.6e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW81636.1 - 9.2e-08 32.2 1.4 2.6e-07 30.7 0.6 2.1 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Ras PF00071.17 EIW81637.1 - 7.5e-55 184.7 0.0 8.6e-55 184.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW81637.1 - 6.8e-16 58.8 0.0 9.1e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW81637.1 - 5.2e-07 29.0 0.0 8.3e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EIW81637.1 - 0.0018 17.5 0.0 0.0024 17.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EIW81637.1 - 0.05 12.7 0.0 0.065 12.3 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EIW81637.1 - 0.057 12.8 0.0 11 5.4 0.0 2.5 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation His_Phos_2 PF00328.17 EIW81638.1 - 1.3e-17 64.1 0.0 2e-17 63.5 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) F-box-like PF12937.2 EIW81639.1 - 3.7e-08 32.9 4.2 3.7e-08 32.9 2.9 2.0 2 0 0 2 2 2 1 F-box-like F-box-like_2 PF13013.1 EIW81639.1 - 0.084 12.6 1.3 0.22 11.2 0.9 1.7 1 0 0 1 1 1 0 F-box-like domain F-box-like PF12937.2 EIW81640.1 - 4.6e-08 32.6 0.8 1e-07 31.5 0.5 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIW81640.1 - 0.083 12.5 2.5 0.66 9.6 1.8 2.5 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) BPL_LplA_LipB PF03099.14 EIW81642.1 - 2.7e-08 33.8 0.1 3.5e-07 30.2 0.1 2.2 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 EIW81642.1 - 0.0072 15.9 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Sugar_tr PF00083.19 EIW81644.1 - 3.2e-39 134.7 18.2 4.3e-39 134.3 12.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW81644.1 - 1e-19 70.5 30.9 2.8e-13 49.3 4.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PrgI PF12666.2 EIW81644.1 - 0.26 11.4 4.4 3.7 7.7 0.0 3.7 3 0 0 3 3 3 0 PrgI family protein Glyco_hydro_15 PF00723.16 EIW81645.1 - 2.9e-50 171.1 0.0 4.8e-50 170.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 Complex1_51K PF01512.12 EIW81647.1 - 2.2e-47 160.5 0.0 3.1e-47 160.0 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EIW81647.1 - 7e-20 69.9 0.9 7e-20 69.9 0.6 2.0 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EIW81647.1 - 7.3e-09 35.3 0.0 2.3e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 SLBB domain Dapper PF15268.1 EIW81651.1 - 0.095 11.4 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 Dapper MecA PF05389.7 EIW81653.1 - 0.099 12.1 0.8 0.11 12.0 0.5 1.0 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) ApoL PF05461.6 EIW81656.1 - 0.092 11.9 0.0 0.61 9.2 0.0 2.0 1 1 0 1 1 1 0 Apolipoprotein L ODV-E18 PF10717.4 EIW81660.1 - 0.013 14.9 0.1 0.025 14.0 0.1 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Cytochrom_D1 PF02239.11 EIW81661.1 - 0.0046 15.3 0.0 0.026 12.8 0.0 2.0 2 0 0 2 2 2 1 Cytochrome D1 heme domain Pkinase PF00069.20 EIW81662.1 - 1.3e-37 129.4 0.0 1.7e-37 129.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW81662.1 - 7.2e-32 110.4 0.0 9.7e-32 110.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 EIW81662.1 - 0.0032 16.3 0.0 0.0058 15.4 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EIW81662.1 - 0.0048 16.6 0.0 0.0077 15.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIW81662.1 - 0.072 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Apc4 PF12896.2 EIW81663.1 - 0.048 12.9 0.2 0.067 12.4 0.1 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 4 P2_Phage_GpR PF06891.6 EIW81663.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 P2 phage tail completion protein R (GpR) Pkinase PF00069.20 EIW81664.1 - 2.7e-39 134.9 0.0 3.3e-39 134.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW81664.1 - 3.8e-36 124.4 0.0 4.5e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EIW81664.1 - 0.0026 17.1 0.1 0.01 15.2 0.0 1.9 3 0 0 3 3 3 1 RIO1 family APH PF01636.18 EIW81664.1 - 0.0035 17.1 0.3 0.014 15.1 0.1 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EIW81664.1 - 0.004 16.0 0.0 0.0062 15.4 0.0 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 zf-C2H2 PF00096.21 EIW81666.1 - 1.8e-10 40.4 10.7 7e-05 22.9 2.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW81666.1 - 4.7e-09 36.0 4.5 0.00039 20.5 0.1 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIW81666.1 - 7.8e-07 28.9 11.6 0.0019 18.4 0.6 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIW81666.1 - 0.0028 17.7 0.4 0.0028 17.7 0.3 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIW81666.1 - 0.029 14.5 0.4 0.029 14.5 0.3 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EIW81666.1 - 0.09 12.7 1.0 0.18 11.7 0.2 1.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EIW81666.1 - 0.097 12.3 10.4 0.61 9.8 2.6 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Hydrolase_6 PF13344.1 EIW81668.1 - 7.4e-12 45.0 0.0 1.7e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIW81668.1 - 9.8e-08 31.6 0.0 2.7e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EIW81668.1 - 0.0011 19.4 0.0 0.5 10.7 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIW81668.1 - 0.013 15.7 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Abhydrolase_6 PF12697.2 EIW81670.1 - 1.2e-11 44.9 1.1 1.5e-11 44.6 0.7 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW81670.1 - 0.0019 17.9 0.0 0.0026 17.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EIW81670.1 - 0.056 12.8 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.15 EIW81670.1 - 0.072 12.6 0.3 3.3 7.2 0.2 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Lipase PF00151.14 EIW81670.1 - 0.084 12.0 0.1 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Lipase IncA PF04156.9 EIW81671.1 - 0.15 11.5 0.1 1.7 8.1 0.0 2.3 3 0 0 3 3 3 0 IncA protein 5TM-5TMR_LYT PF07694.7 EIW81671.1 - 3 7.1 15.5 0.05 12.9 2.4 3.2 1 1 2 3 3 3 0 5TMR of 5TMR-LYT Nop14 PF04147.7 EIW81672.1 - 2.8 5.7 15.0 4.8 4.9 10.4 1.3 1 0 0 1 1 1 0 Nop14-like family DUF3311 PF11755.3 EIW81673.1 - 0.16 11.5 0.1 0.16 11.5 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3311) Glyco_hydro_3 PF00933.16 EIW81674.1 - 2.4e-62 210.6 0.0 3.3e-62 210.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIW81674.1 - 1.2e-51 175.3 0.0 2e-51 174.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIW81674.1 - 1.2e-22 79.5 0.3 2.7e-22 78.4 0.2 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain CBFD_NFYB_HMF PF00808.18 EIW81676.1 - 4.2e-21 74.7 0.8 6.4e-21 74.1 0.6 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EIW81676.1 - 5.1e-09 36.1 0.0 7.2e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EIW81676.1 - 0.0021 17.8 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 CENP-S associating Centromere protein X TAF PF02969.12 EIW81676.1 - 0.071 13.0 0.2 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) DnaJ PF00226.26 EIW81677.1 - 9.5e-21 73.3 1.1 6.9e-20 70.5 0.3 2.6 3 0 0 3 3 3 1 DnaJ domain TPR_11 PF13414.1 EIW81677.1 - 3e-12 46.0 10.1 2.6e-09 36.6 0.1 4.2 3 1 1 4 4 4 3 TPR repeat TPR_2 PF07719.12 EIW81677.1 - 6.7e-12 44.3 10.1 0.0057 16.4 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 EIW81677.1 - 1.1e-11 43.7 5.6 0.0042 16.6 0.0 4.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIW81677.1 - 4.5e-09 36.7 13.9 0.0069 17.0 0.0 5.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIW81677.1 - 1.1e-08 34.9 18.7 0.27 11.9 0.0 6.9 4 3 4 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 EIW81677.1 - 6.7e-07 29.0 0.2 0.026 14.6 0.0 5.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIW81677.1 - 7.6e-07 28.4 1.7 0.72 9.8 0.0 4.8 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIW81677.1 - 2e-06 27.1 0.0 3 7.8 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_6 PF13174.1 EIW81677.1 - 1.1e-05 25.5 10.8 2.7 8.6 0.0 5.8 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_9 PF13371.1 EIW81677.1 - 8e-05 22.4 4.5 0.011 15.5 0.0 4.3 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EIW81677.1 - 0.00012 22.3 9.1 0.16 12.2 0.0 5.0 3 2 3 6 6 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIW81677.1 - 0.00069 19.5 11.1 0.079 12.9 0.0 4.8 3 2 3 6 6 6 3 Tetratricopeptide repeat 2-Hacid_dh_C PF02826.14 EIW81678.1 - 8.2e-46 155.3 0.0 1.2e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIW81678.1 - 2.8e-20 72.1 0.0 3.5e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EIW81678.1 - 6.9e-07 29.2 0.0 5.9e-06 26.2 0.0 2.1 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.1 EIW81678.1 - 0.0045 17.2 0.1 4.9 7.4 0.0 3.7 4 0 0 4 4 4 1 Putative NAD(P)-binding p450 PF00067.17 EIW81679.1 - 2.1e-69 234.2 0.0 2.3e-68 230.8 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Phage_lysis PF03245.8 EIW81680.1 - 0.28 11.1 8.1 0.068 13.1 3.2 1.8 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein TMF_TATA_bd PF12325.3 EIW81680.1 - 0.5 10.1 9.2 8.5 6.1 6.4 2.4 1 1 0 1 1 1 0 TATA element modulatory factor 1 TATA binding IncA PF04156.9 EIW81680.1 - 4.7 6.7 9.4 19 4.7 6.5 1.9 1 1 0 1 1 1 0 IncA protein p450 PF00067.17 EIW81682.1 - 4.7e-78 262.7 0.0 5.7e-78 262.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EIW81684.1 - 5.5e-68 229.6 0.0 7.2e-68 229.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EIW81684.1 - 1.9e-05 23.8 0.1 3.7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EIW81684.1 - 0.00012 21.0 0.1 0.0023 16.8 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EIW81684.1 - 0.00029 20.8 0.1 0.00095 19.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIW81684.1 - 0.00044 20.3 0.0 0.00094 19.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW81684.1 - 0.0011 18.8 0.0 0.0049 16.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW81684.1 - 0.0017 16.9 0.9 0.002 16.6 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 EIW81684.1 - 0.0017 17.3 0.0 0.0029 16.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EIW81684.1 - 0.0018 16.9 0.5 0.0042 15.7 0.1 1.7 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox PF00070.22 EIW81684.1 - 0.0094 16.3 0.2 0.12 12.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EIW81684.1 - 0.027 14.7 0.0 0.16 12.2 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.17 EIW81684.1 - 0.15 10.8 0.1 0.23 10.2 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A F-box-like PF12937.2 EIW81685.1 - 5.9e-08 32.3 0.7 1.6e-07 30.8 0.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW81685.1 - 0.061 13.0 0.2 0.57 9.9 0.0 2.4 2 0 0 2 2 2 0 F-box domain TIP49 PF06068.8 EIW81686.1 - 9.4e-173 574.4 0.0 1.1e-172 574.2 0.0 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EIW81686.1 - 1.7e-09 37.9 0.1 3.2e-06 27.3 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIW81686.1 - 6.2e-09 35.2 0.0 2.8e-07 29.8 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EIW81686.1 - 9.1e-07 29.0 0.0 1.3e-05 25.3 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EIW81686.1 - 5e-06 26.2 0.1 0.0027 17.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EIW81686.1 - 9.7e-06 25.7 0.1 0.05 13.7 0.1 2.6 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EIW81686.1 - 0.0003 20.4 0.1 0.001 18.7 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EIW81686.1 - 0.00079 19.3 0.0 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EIW81686.1 - 0.00098 19.1 0.1 0.0037 17.2 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EIW81686.1 - 0.0013 18.1 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EIW81686.1 - 0.0025 17.2 0.1 0.0079 15.6 0.1 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activat PF00158.21 EIW81686.1 - 0.012 15.1 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.1 EIW81686.1 - 0.017 15.0 0.0 6.9 6.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EIW81686.1 - 0.018 14.2 0.0 0.1 11.7 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EIW81686.1 - 0.02 14.0 0.1 0.047 12.7 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EIW81686.1 - 0.047 14.5 0.0 0.1 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EIW81686.1 - 0.075 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.17 EIW81686.1 - 0.097 12.1 0.1 6.5 6.1 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NACHT PF05729.7 EIW81686.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain Parvo_NS1 PF01057.12 EIW81686.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ResIII PF04851.10 EIW81686.1 - 0.18 11.6 0.0 1.3 8.8 0.0 2.1 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PNP_UDP_1 PF01048.15 EIW81687.1 - 1.1e-35 122.6 0.0 1.4e-35 122.3 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily DUF4193 PF13834.1 EIW81687.1 - 0.16 12.1 0.1 0.34 11.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4193) PPP5 PF08321.7 EIW81687.1 - 0.17 11.8 0.1 0.46 10.5 0.0 1.6 2 0 0 2 2 2 0 PPP5 TPR repeat region Methyltransf_11 PF08241.7 EIW81690.1 - 1.6e-24 86.2 0.1 2.8e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW81690.1 - 2e-23 82.6 0.0 3e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW81690.1 - 2.7e-17 63.0 0.0 4.2e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW81690.1 - 9.8e-17 60.8 0.0 1.3e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EIW81690.1 - 5.4e-16 58.8 0.0 8.8e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW81690.1 - 2.3e-15 56.6 0.0 3.1e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW81690.1 - 2.6e-15 56.9 0.0 4.5e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIW81690.1 - 1.2e-09 38.0 0.0 1.7e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EIW81690.1 - 2.4e-09 37.2 0.5 4.9e-09 36.2 0.4 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW81690.1 - 4.5e-08 32.6 0.0 6.9e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EIW81690.1 - 1.9e-06 27.0 0.0 2.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.6 EIW81690.1 - 4.9e-05 22.1 0.0 7.4e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MetW PF07021.7 EIW81690.1 - 7.4e-05 22.2 0.0 0.00019 20.8 0.0 1.6 1 1 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.8 EIW81690.1 - 0.00027 20.1 0.0 0.00036 19.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EIW81690.1 - 0.00058 19.8 0.0 0.00084 19.3 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase RrnaAD PF00398.15 EIW81690.1 - 0.00062 18.8 0.0 0.00086 18.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase CMAS PF02353.15 EIW81690.1 - 0.0017 17.4 0.0 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.10 EIW81690.1 - 0.0024 17.5 0.0 0.016 14.8 0.0 1.9 2 0 0 2 2 2 1 Hypothetical methyltransferase NodS PF05401.6 EIW81690.1 - 0.0035 16.7 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 EIW81690.1 - 0.013 15.1 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DREV PF05219.7 EIW81690.1 - 0.02 13.7 0.0 0.03 13.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase UPF0020 PF01170.13 EIW81690.1 - 0.026 14.1 0.0 0.042 13.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 CheR PF01739.13 EIW81690.1 - 0.044 13.0 0.0 2.1 7.5 0.0 2.1 1 1 0 2 2 2 0 CheR methyltransferase, SAM binding domain Methyltransf_29 PF03141.11 EIW81690.1 - 0.048 12.0 0.0 0.072 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase IMPDH PF00478.20 EIW81691.1 - 1.1e-134 448.8 0.0 3.3e-134 447.2 0.0 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EIW81691.1 - 5.5e-12 45.2 0.1 9.6e-05 22.0 0.0 2.5 2 0 0 2 2 2 2 CBS domain FMN_dh PF01070.13 EIW81691.1 - 3.5e-11 42.5 0.7 9e-11 41.2 0.4 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 EIW81691.1 - 4.3e-10 39.2 2.5 9.4e-08 31.5 1.3 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase ThiG PF05690.9 EIW81691.1 - 0.00026 20.1 2.7 0.0003 19.9 0.9 1.8 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EIW81691.1 - 0.00045 19.5 3.5 0.00045 19.5 2.4 2.9 3 1 0 3 3 3 1 Histidine biosynthesis protein DUF561 PF04481.7 EIW81691.1 - 0.057 12.3 1.1 0.57 9.0 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF561) Formyl_trans_C PF02911.13 EIW81691.1 - 0.15 12.1 0.3 35 4.5 0.0 3.4 3 0 0 3 3 3 0 Formyl transferase, C-terminal domain DUF1273 PF06908.6 EIW81691.1 - 0.19 11.3 0.0 0.32 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1273) SH3_9 PF14604.1 EIW81693.1 - 1.2e-05 24.7 0.0 2.4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIW81693.1 - 0.001 18.3 0.0 0.0019 17.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIW81693.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 Variant SH3 domain RNase_H PF00075.19 EIW81694.1 - 2.7e-07 30.9 0.4 2.1e-05 24.8 0.1 2.4 1 1 1 2 2 2 2 RNase H RVT_3 PF13456.1 EIW81694.1 - 3.2e-07 30.0 0.2 1.1e-06 28.3 0.1 1.8 1 1 1 2 2 2 1 Reverse transcriptase-like RVT_3 PF13456.1 EIW81695.1 - 1.5e-05 24.6 0.4 2.8e-05 23.8 0.1 1.5 2 0 0 2 2 2 1 Reverse transcriptase-like RNase_H PF00075.19 EIW81695.1 - 0.00012 22.3 0.2 0.00036 20.8 0.1 1.7 1 1 0 1 1 1 1 RNase H GATA PF00320.22 EIW81696.1 - 0.038 13.3 3.0 1.6 8.0 0.3 2.4 2 0 0 2 2 2 0 GATA zinc finger Peptidase_A4 PF01828.12 EIW81698.1 - 3.2e-69 232.1 14.5 3.6e-69 232.0 10.0 1.0 1 0 0 1 1 1 1 Peptidase A4 family C6 PF01681.12 EIW81698.1 - 4 7.5 9.4 1.2 9.2 4.1 1.9 1 1 1 2 2 2 0 C6 domain IncA PF04156.9 EIW81699.1 - 0.0045 16.6 3.2 0.013 15.1 2.2 1.8 1 0 0 1 1 1 1 IncA protein Exo_endo_phos PF03372.18 EIW81701.1 - 1.8e-22 80.4 0.1 3e-22 79.7 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 EIW81702.1 - 2.8e-114 369.3 25.4 2.7e-12 46.0 0.0 11.2 11 0 0 11 11 11 11 WD domain, G-beta repeat PD40 PF07676.7 EIW81702.1 - 4.9e-11 42.0 1.2 1.6 8.4 0.0 8.7 9 0 0 9 9 9 1 WD40-like Beta Propeller Repeat Nup160 PF11715.3 EIW81702.1 - 4.2e-10 38.3 10.1 0.25 9.4 0.1 7.3 2 2 4 7 7 7 5 Nucleoporin Nup120/160 eIF2A PF08662.6 EIW81702.1 - 4.1e-09 36.4 0.0 0.0026 17.4 0.0 4.4 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EIW81702.1 - 6.7e-08 32.2 3.0 0.045 13.1 0.4 4.6 2 2 1 3 3 3 3 PQQ-like domain Nucleoporin_N PF08801.6 EIW81702.1 - 7.4e-07 28.2 8.2 0.024 13.3 0.2 5.6 2 2 1 4 4 4 2 Nup133 N terminal like Proteasome_A_N PF10584.4 EIW81702.1 - 1.1e-05 24.6 2.2 4.1 6.8 0.0 6.5 7 0 0 7 7 7 1 Proteasome subunit A N-terminal signature BBS2_Mid PF14783.1 EIW81702.1 - 5.3e-05 22.9 0.0 7.7 6.3 0.0 5.7 6 1 1 7 7 7 1 Ciliary BBSome complex subunit 2, middle region Gmad1 PF10647.4 EIW81702.1 - 0.0011 18.3 9.0 0.0075 15.6 0.2 3.8 2 1 1 3 3 3 1 Lipoprotein LpqB beta-propeller domain Me-amine-dh_H PF06433.6 EIW81702.1 - 0.054 12.1 0.0 75 1.7 0.0 4.4 5 1 1 6 6 6 0 Methylamine dehydrogenase heavy chain (MADH) WD40 PF00400.27 EIW81705.1 - 2e-80 262.0 24.1 1.3e-12 47.0 0.0 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat Nup160 PF11715.3 EIW81705.1 - 4.6e-10 38.2 5.4 0.13 10.3 0.0 5.4 3 1 3 6 6 6 4 Nucleoporin Nup120/160 PD40 PF07676.7 EIW81705.1 - 1.7e-08 33.9 0.6 2.8 7.6 0.0 6.1 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EIW81705.1 - 4.8e-07 29.6 0.0 0.056 13.1 0.0 3.6 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 EIW81705.1 - 4.4e-05 22.6 0.1 25 4.3 0.0 5.7 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.11 EIW81705.1 - 5.4e-05 21.6 0.1 0.12 10.5 0.0 3.0 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 EIW81705.1 - 0.0036 16.0 0.1 1.8 7.2 0.0 3.9 1 1 0 2 2 2 1 Nup133 N terminal like Apc4_WD40 PF12894.2 EIW81705.1 - 0.023 14.2 0.0 1.7 8.2 0.0 3.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Me-amine-dh_H PF06433.6 EIW81705.1 - 0.093 11.3 0.0 2.8 6.4 0.0 2.8 3 0 0 3 3 3 0 Methylamine dehydrogenase heavy chain (MADH) DUF3312 PF11768.3 EIW81705.1 - 0.18 10.0 0.0 0.31 9.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) CsbD PF05532.7 EIW81706.1 - 4.2e-14 51.9 14.2 2.1e-08 33.7 1.8 2.1 1 1 1 2 2 2 2 CsbD-like ALF PF03752.8 EIW81708.1 - 0.016 15.0 0.2 0.039 13.7 0.2 1.6 1 0 0 1 1 1 0 Short repeats of unknown function Amidase PF01425.16 EIW81709.1 - 5.8e-81 272.5 0.0 8.7e-79 265.4 0.0 2.0 1 1 0 1 1 1 1 Amidase Pkinase PF00069.20 EIW81711.1 - 4.6e-34 117.7 0.0 5.8e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW81711.1 - 8.9e-27 93.7 0.0 2.3e-25 89.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW81711.1 - 4.8e-05 22.4 0.0 7.7e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIW81711.1 - 0.00058 18.9 0.1 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW81711.1 - 0.012 15.3 1.5 0.015 15.0 0.3 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF1469 PF07332.6 EIW81712.1 - 1.1 8.9 4.0 0.26 11.0 0.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) DUF3328 PF11807.3 EIW81715.1 - 2.8e-18 66.4 0.3 3.2e-18 66.1 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF1477 PF07346.6 EIW81715.1 - 0.044 13.8 0.0 0.068 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1477) DUF1498 PF07385.7 EIW81715.1 - 0.09 11.8 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1498) DUF3328 PF11807.3 EIW81717.1 - 2.5e-22 79.6 0.2 2.9e-22 79.4 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) MFS_1 PF07690.11 EIW81718.1 - 9.4e-39 133.1 38.8 9.4e-39 133.1 26.9 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EIW81718.1 - 2.1e-13 49.3 14.4 4.2e-13 48.3 10.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIW81718.1 - 4.6e-09 35.3 10.3 4.6e-09 35.3 7.1 3.9 2 1 3 5 5 5 2 Sugar (and other) transporter MFS_3 PF05977.8 EIW81718.1 - 4e-06 25.2 15.3 9.6e-05 20.6 0.9 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector Pkinase_Tyr PF07714.12 EIW81719.1 - 6.3e-07 28.7 0.0 0.0032 16.5 0.0 2.7 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 EIW81719.1 - 1.4e-06 27.6 0.0 3.6e-05 23.0 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Transposase_21 PF02992.9 EIW81720.1 - 1.8e-10 40.3 0.0 3.4e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EIW81720.1 - 0.0034 16.8 0.1 0.0078 15.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) SHNi-TPR PF10516.4 EIW81722.1 - 0.038 13.2 0.1 5.7 6.2 0.0 2.8 2 0 0 2 2 2 0 SHNi-TPR Dimer_Tnp_hAT PF05699.9 EIW81724.1 - 3.4e-14 52.2 0.0 3.6e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Nterm_IS4 PF13006.2 EIW81724.1 - 0.11 12.5 0.0 0.12 12.4 0.0 1.1 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal DUF3328 PF11807.3 EIW81726.1 - 7e-21 74.9 0.1 9e-21 74.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DNA_binding_1 PF01035.15 EIW81728.1 - 6e-24 83.6 0.0 2.1e-23 81.8 0.0 1.8 1 1 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Tcf25 PF04910.9 EIW81729.1 - 4.2e-70 236.5 0.0 6.1e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TPR_12 PF13424.1 EIW81729.1 - 0.0052 16.6 0.1 0.016 15.1 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat HET PF06985.6 EIW81730.1 - 8.5e-17 61.6 1.0 4.2e-13 49.6 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 EIW81731.1 - 6e-18 64.6 28.8 7.6e-18 64.3 18.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 EIW81731.1 - 1.7e-15 56.9 1.7 1.7e-15 56.9 1.2 1.6 2 0 0 2 2 2 1 Nodulin-like 4HB_MCP_1 PF12729.2 EIW81731.1 - 0.12 11.7 0.0 0.27 10.5 0.0 1.5 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Acetyltransf_1 PF00583.19 EIW81732.1 - 5.9e-11 42.2 0.0 1.5e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EIW81732.1 - 6.5e-08 32.2 0.0 1.1e-06 28.2 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.1 EIW81732.1 - 1.1e-07 31.8 0.0 3.8e-07 30.1 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIW81732.1 - 3.5e-05 23.9 0.0 0.00076 19.5 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIW81732.1 - 0.00065 19.5 0.0 0.085 12.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Glyoxalase PF00903.20 EIW81732.1 - 0.023 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Acetyltransf_8 PF13523.1 EIW81732.1 - 0.031 14.1 0.0 0.22 11.3 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Abhydrolase_6 PF12697.2 EIW81733.1 - 1.2e-28 100.5 1.5 1.9e-28 99.9 1.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW81733.1 - 1.6e-12 47.5 0.4 4.3e-12 46.0 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW81733.1 - 6.1e-09 35.7 0.1 1.7e-08 34.3 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EIW81733.1 - 0.0099 14.3 0.0 0.013 14.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 EIW81733.1 - 0.028 14.2 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 Putative lysophospholipase GST_N_3 PF13417.1 EIW81734.1 - 0.00012 22.1 0.0 0.00031 20.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW81734.1 - 0.0017 18.1 0.5 0.0037 17.1 0.3 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW81734.1 - 0.023 14.6 0.0 0.066 13.2 0.0 1.7 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain MethyTransf_Reg PF10119.4 EIW81734.1 - 0.04 14.4 0.1 0.51 10.8 0.0 2.2 2 0 0 2 2 2 0 Predicted methyltransferase regulatory domain NACHT PF05729.7 EIW81736.1 - 5.4e-09 35.9 0.1 1.1e-08 34.8 0.0 1.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW81736.1 - 7.7e-08 32.5 1.1 1.3e-07 31.7 0.8 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW81736.1 - 3.1e-05 24.1 0.0 4.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EIW81736.1 - 7.2e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase KAP_NTPase PF07693.9 EIW81736.1 - 0.00015 20.8 3.3 0.0069 15.4 0.6 2.0 1 1 1 2 2 2 2 KAP family P-loop domain RNA_helicase PF00910.17 EIW81736.1 - 0.00024 21.2 0.0 0.00044 20.3 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 EIW81736.1 - 0.00025 21.3 0.0 0.00035 20.8 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EIW81736.1 - 0.0003 20.9 0.2 0.0022 18.1 0.2 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIW81736.1 - 0.002 18.9 0.0 0.003 18.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain KTI12 PF08433.5 EIW81736.1 - 0.013 14.7 0.3 0.027 13.6 0.2 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 EIW81736.1 - 0.018 14.8 0.1 0.027 14.3 0.1 1.4 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIW81736.1 - 0.035 14.4 0.0 0.046 14.0 0.0 1.4 1 1 0 1 1 1 0 ABC transporter PRK PF00485.13 EIW81736.1 - 0.04 13.4 0.0 0.043 13.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family TIP49 PF06068.8 EIW81736.1 - 0.041 12.6 0.1 0.049 12.3 0.1 1.3 1 1 0 1 1 1 0 TIP49 C-terminus Cytidylate_kin2 PF13189.1 EIW81736.1 - 0.042 13.7 0.4 0.083 12.7 0.3 1.9 1 1 0 1 1 1 0 Cytidylate kinase-like family AAA_5 PF07728.9 EIW81736.1 - 0.046 13.4 0.1 0.11 12.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) UPF0079 PF02367.12 EIW81736.1 - 0.067 12.8 0.0 0.076 12.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 CbiA PF01656.18 EIW81736.1 - 0.069 12.5 0.3 0.094 12.1 0.2 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EIW81736.1 - 0.072 12.8 0.0 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF2075 PF09848.4 EIW81736.1 - 0.081 11.8 0.0 0.098 11.6 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 EIW81736.1 - 0.091 12.1 0.0 0.19 11.1 0.0 1.3 1 1 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 EIW81736.1 - 0.092 12.2 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NTPase_1 PF03266.10 EIW81736.1 - 0.093 12.4 0.0 0.17 11.5 0.0 1.6 1 1 0 1 1 1 0 NTPase Zeta_toxin PF06414.7 EIW81736.1 - 0.1 11.6 0.1 0.19 10.7 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin Sigma54_activat PF00158.21 EIW81736.1 - 0.13 11.7 0.1 0.25 10.8 0.0 1.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Glyco_hydro_85 PF03644.8 EIW81737.1 - 3.7e-73 246.3 0.0 6.6e-73 245.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 CBM_5_12 PF02839.9 EIW81738.1 - 3.3e-06 26.5 8.4 3.3e-06 26.5 5.8 4.4 4 2 1 5 5 5 2 Carbohydrate binding domain Suf PF05843.9 EIW81739.1 - 7.3e-56 189.9 0.7 9.6e-52 176.4 0.0 3.4 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EIW81739.1 - 1.3e-10 41.4 1.9 0.071 13.4 0.1 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIW81739.1 - 5.5e-10 38.9 14.6 0.0027 18.2 0.2 7.8 4 3 3 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIW81739.1 - 1.6e-07 31.8 11.1 0.019 15.6 0.1 4.3 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_15 PF13429.1 EIW81739.1 - 2.2e-05 23.6 2.9 0.033 13.2 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIW81739.1 - 0.0037 17.6 4.0 1.1 9.8 0.0 5.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIW81739.1 - 0.0038 16.8 0.2 0.0038 16.8 0.1 2.8 3 0 0 3 3 3 1 TPR repeat FTCD_C PF04961.7 EIW81739.1 - 0.044 13.1 0.0 0.09 12.1 0.0 1.4 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase Mad3_BUB1_I PF08311.7 EIW81739.1 - 5.4 6.8 11.9 1.5 8.6 0.1 4.2 4 1 0 4 4 4 0 Mad3/BUB1 homology region 1 AAA PF00004.24 EIW81740.1 - 3.7e-46 156.5 0.0 2.6e-41 140.9 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIW81740.1 - 2.2e-06 27.7 0.0 2.2e-06 27.7 0.0 3.7 5 0 0 5 5 4 1 AAA ATPase domain IstB_IS21 PF01695.12 EIW81740.1 - 1.5e-05 24.4 0.0 4.2e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 EIW81740.1 - 2.1e-05 24.4 0.0 4.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EIW81740.1 - 0.00014 21.9 0.0 0.0039 17.3 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EIW81740.1 - 0.00018 21.2 0.0 0.0017 18.0 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EIW81740.1 - 0.0004 20.0 1.0 0.0065 16.2 0.1 3.1 3 0 0 3 3 3 1 Part of AAA domain AAA_25 PF13481.1 EIW81740.1 - 0.0064 15.9 0.3 0.038 13.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EIW81740.1 - 0.0069 17.1 0.1 0.031 15.0 0.0 2.2 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EIW81740.1 - 0.0075 16.5 0.3 0.049 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EIW81740.1 - 0.0084 15.9 0.0 0.0084 15.9 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 EIW81740.1 - 0.021 14.8 0.0 0.055 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EIW81740.1 - 0.028 13.6 0.0 0.087 12.0 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein RuvB_N PF05496.7 EIW81740.1 - 0.043 12.8 0.0 0.088 11.8 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Mg_chelatase PF01078.16 EIW81740.1 - 0.046 12.8 0.1 0.12 11.5 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EIW81740.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EIW81740.1 - 0.082 12.9 0.0 0.93 9.5 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain TIP49 PF06068.8 EIW81740.1 - 0.09 11.4 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus RNA_helicase PF00910.17 EIW81740.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.21 EIW81740.1 - 0.12 11.8 0.0 1.5 8.3 0.0 2.5 3 0 0 3 3 3 0 Sigma-54 interaction domain DUF2075 PF09848.4 EIW81740.1 - 0.16 10.9 0.0 0.36 9.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.12 EIW81740.1 - 0.23 10.2 0.0 0.39 9.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Torsin PF06309.6 EIW81740.1 - 0.25 11.2 0.0 5.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Torsin NACHT PF05729.7 EIW81740.1 - 0.29 10.7 0.5 0.66 9.6 0.0 2.0 2 1 0 2 2 1 0 NACHT domain U79_P34 PF03064.11 EIW81740.1 - 3.5 7.0 5.7 6 6.3 4.0 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 zf-C2H2_4 PF13894.1 EIW81742.1 - 0.015 15.5 0.2 0.021 15.1 0.1 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIW81742.1 - 0.11 12.4 0.4 0.14 12.0 0.3 1.2 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EIW81742.1 - 0.11 12.8 1.0 0.15 12.4 0.7 1.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type Sugar_tr PF00083.19 EIW81743.1 - 1.7e-97 326.8 24.3 1.9e-97 326.6 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW81743.1 - 7.1e-18 64.4 33.8 2.3e-14 52.8 4.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EIW81743.1 - 0.003 17.5 8.0 0.11 12.5 0.4 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1228) Anti-adapt_IraP PF10796.4 EIW81743.1 - 0.079 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-S stabilisation anti-adaptor protein OATP PF03137.15 EIW81743.1 - 0.28 9.2 9.3 1.5 6.7 0.5 2.3 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1 PF07690.11 EIW81744.1 - 4.3e-32 111.2 24.1 4.3e-32 111.2 16.7 3.0 2 2 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW81744.1 - 0.0013 17.4 13.5 0.0013 17.4 9.3 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EIW81744.1 - 0.012 13.6 3.8 0.017 13.1 0.6 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family BT1 PF03092.11 EIW81744.1 - 0.026 13.2 2.8 0.065 11.9 1.9 1.7 1 1 0 1 1 1 0 BT1 family Beta-lactamase PF00144.19 EIW81745.1 - 5.1e-22 78.3 0.1 6.6e-22 77.9 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase F-box-like PF12937.2 EIW81746.1 - 9.4e-06 25.2 1.7 6e-05 22.6 1.2 2.3 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EIW81746.1 - 0.53 10.0 5.9 15 5.4 0.1 3.6 3 0 0 3 3 3 0 F-box domain GST_N_3 PF13417.1 EIW81747.1 - 1.1e-13 51.1 0.1 2e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW81747.1 - 4.4e-11 42.6 0.0 6.9e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW81747.1 - 1.1e-07 31.6 0.0 1.8e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW81747.1 - 0.0057 16.6 0.0 0.0094 15.9 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW81747.1 - 0.15 12.5 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain F-box-like PF12937.2 EIW81748.1 - 1.1e-05 25.0 6.4 1.1e-05 25.0 4.4 4.4 3 2 0 3 3 3 1 F-box-like F-box PF00646.28 EIW81748.1 - 1.5 8.5 6.8 1.5 8.6 0.3 3.5 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 EIW81751.1 - 0.031 13.9 10.3 0.054 13.2 3.7 3.2 2 1 0 2 2 2 0 F-box-like NTP_transf_3 PF12804.2 EIW81751.1 - 0.065 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 MobA-like NTP transferase domain F-box PF00646.28 EIW81751.1 - 1.4 8.6 9.0 1.1 9.0 0.2 4.0 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 EIW81752.1 - 1.1e-05 25.0 6.3 0.00051 19.6 5.2 2.9 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 EIW81752.1 - 0.0091 15.6 1.8 0.45 10.2 0.1 3.0 2 0 0 2 2 2 1 F-box domain NUFIP1 PF10453.4 EIW81752.1 - 0.052 13.0 0.8 0.087 12.3 0.0 1.7 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Anoctamin PF04547.7 EIW81754.1 - 4.4e-94 315.6 0.0 6.8e-94 315.0 0.0 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel PGA2 PF07543.7 EIW81754.1 - 0.33 10.7 2.0 0.43 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein trafficking PGA2 DUF3533 PF12051.3 EIW81756.1 - 3.6e-60 203.7 15.1 4.3e-60 203.4 10.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Peptidase_S10 PF00450.17 EIW81757.1 - 3.1e-77 260.5 0.0 4.9e-77 259.8 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase SNO PF01174.14 EIW81757.1 - 7.8e-27 94.1 0.0 2.8e-24 85.8 0.0 3.2 1 1 0 1 1 1 1 SNO glutamine amidotransferase family Trypan_PARP PF05887.6 EIW81758.1 - 5.7 6.7 9.8 3 7.6 5.0 1.8 1 1 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PAT1 PF09770.4 EIW81758.1 - 7 4.7 15.3 7.6 4.6 10.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RRM_1 PF00076.17 EIW81759.1 - 6.4e-35 118.6 0.3 1.3e-16 59.9 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW81759.1 - 4.5e-28 97.0 0.3 3.5e-14 52.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW81759.1 - 4.5e-12 45.6 0.2 1.8e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIW81759.1 - 0.042 13.6 0.0 8.7 6.2 0.0 2.3 2 0 0 2 2 2 0 RNA binding motif DUF3328 PF11807.3 EIW81760.1 - 9.3e-17 61.4 0.0 1.9e-16 60.4 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EIW81761.1 - 3e-22 79.3 0.5 3.1e-22 79.3 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Gln-synt_C PF00120.19 EIW81762.1 - 3.3e-51 173.9 0.0 4.1e-51 173.6 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain SPOR PF05036.8 EIW81762.1 - 0.081 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Sporulation related domain RFC1 PF08519.7 EIW81766.1 - 2.2e-49 167.1 0.0 2.4e-48 163.7 0.0 2.4 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EIW81766.1 - 2.9e-15 56.1 0.0 8.4e-15 54.6 0.0 1.8 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EIW81766.1 - 7.9e-09 35.8 0.0 2.6e-08 34.1 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EIW81766.1 - 3.3e-06 26.0 0.1 9.8e-05 21.2 0.0 2.1 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EIW81766.1 - 0.00063 19.4 0.0 0.004 16.8 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EIW81766.1 - 0.0044 17.1 0.0 0.017 15.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW81766.1 - 0.0089 16.0 0.0 0.026 14.5 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EIW81766.1 - 0.014 16.1 0.2 0.16 12.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain RuvB_N PF05496.7 EIW81766.1 - 0.024 13.6 0.0 0.057 12.4 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 EIW81766.1 - 0.029 13.9 0.2 0.1 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EIW81766.1 - 0.034 13.8 0.0 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EIW81766.1 - 0.04 13.8 0.0 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EIW81766.1 - 0.049 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 NTPase AAA_33 PF13671.1 EIW81766.1 - 0.069 13.0 0.5 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EIW81766.1 - 0.11 12.1 0.0 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 NACHT domain F-box-like PF12937.2 EIW81767.1 - 0.0011 18.6 0.3 0.0036 17.0 0.0 2.0 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 EIW81772.1 - 1.2e-05 24.9 0.0 3.1e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like adh_short PF00106.20 EIW81773.1 - 2.3e-23 82.9 3.5 4.6e-23 81.9 2.4 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW81773.1 - 3.1e-11 43.2 3.2 1.7e-10 40.8 2.0 2.1 2 1 0 2 2 2 1 KR domain ADH_zinc_N PF00107.21 EIW81773.1 - 0.00036 20.0 0.2 0.00074 19.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EIW81773.1 - 0.0011 19.0 0.4 0.0031 17.5 0.3 1.7 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EIW81773.1 - 0.0021 17.1 0.0 0.0032 16.5 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_Gly3P_dh_N PF01210.18 EIW81773.1 - 0.043 13.5 0.1 2 8.1 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF2163 PF09931.4 EIW81773.1 - 0.07 12.8 0.2 0.55 9.9 0.1 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2163) 3HCDH_N PF02737.13 EIW81773.1 - 0.094 12.3 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EIW81773.1 - 0.12 12.1 0.0 0.38 10.5 0.0 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase PMT PF02366.13 EIW81774.1 - 1.3e-77 260.4 15.9 1.3e-77 260.4 11.0 1.6 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EIW81774.1 - 5.1e-44 150.0 0.1 5.1e-44 150.0 0.1 1.9 2 0 0 2 2 2 1 MIR domain DUF1240 PF06836.7 EIW81774.1 - 0.0028 17.8 0.9 3.5 7.8 0.1 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1240) F-box-like PF12937.2 EIW81775.1 - 2.7e-05 23.8 0.5 6.3e-05 22.6 0.4 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIW81776.1 - 0.0023 17.5 0.4 0.0071 16.0 0.3 1.9 1 0 0 1 1 1 1 F-box-like HD PF01966.17 EIW81777.1 - 3.1e-13 49.7 0.2 4.1e-11 42.9 0.0 2.6 2 0 0 2 2 2 2 HD domain p450 PF00067.17 EIW81779.1 - 7.4e-54 182.9 0.0 2.2e-53 181.4 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW81781.1 - 7.9e-66 222.4 0.0 1.6e-65 221.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW81782.1 - 5e-63 213.2 0.0 1.1e-62 212.1 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 EIW81784.1 - 3.8e-49 162.8 20.3 3.1e-11 42.6 0.3 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW81784.1 - 3.9e-10 39.5 1.8 1.1e-07 31.6 0.2 2.9 1 1 1 2 2 2 2 PQQ-like domain Nup160 PF11715.3 EIW81784.1 - 5.1e-08 31.4 3.0 0.12 10.4 0.0 4.0 2 1 2 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIW81784.1 - 2.7e-05 23.0 1.8 0.36 9.5 0.3 3.8 1 1 1 2 2 2 2 Nup133 N terminal like eIF2A PF08662.6 EIW81784.1 - 4.4e-05 23.2 0.0 0.00066 19.4 0.0 2.4 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EIW81784.1 - 0.0059 16.2 3.7 2.8 7.6 0.0 4.4 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat DUF3312 PF11768.3 EIW81784.1 - 0.014 13.6 0.0 0.13 10.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) GSDH PF07995.6 EIW81784.1 - 0.06 12.4 0.0 5.8 5.9 0.0 2.8 2 1 1 3 3 3 0 Glucose / Sorbosone dehydrogenase Proteasome_A_N PF10584.4 EIW81784.1 - 0.063 12.6 5.3 2.6 7.4 0.0 4.7 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature BBS2_Mid PF14783.1 EIW81784.1 - 0.11 12.2 0.0 4.1 7.2 0.0 2.7 1 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 EIW81784.1 - 0.26 11.6 4.4 22 5.4 0.1 4.6 3 2 2 5 5 5 0 PQQ-like domain Npa1 PF11707.3 EIW81785.1 - 1.6e-55 188.3 0.0 4e-55 187.1 0.0 1.7 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Creb_binding PF09030.5 EIW81785.1 - 0.016 15.3 0.0 0.08 13.1 0.0 2.2 2 0 0 2 2 2 0 Creb binding MFS_1 PF07690.11 EIW81786.1 - 3.8e-17 62.0 34.8 5.3e-17 61.5 24.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 EIW81787.1 - 6.3e-16 58.0 36.9 9.3e-16 57.4 25.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2530 PF10745.4 EIW81787.1 - 0.042 13.8 0.0 0.042 13.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) YrhC PF14143.1 EIW81787.1 - 0.27 11.1 3.0 0.91 9.5 0.0 3.2 3 0 0 3 3 3 0 YrhC-like protein MFS_1 PF07690.11 EIW81789.1 - 3.4e-15 55.6 41.5 4.8e-15 55.1 28.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Nuc_H_symport PF03825.11 EIW81789.1 - 2.6e-07 29.7 2.0 2.6e-07 29.7 1.4 2.3 2 0 0 2 2 2 2 Nucleoside H+ symporter DPBB_1 PF03330.13 EIW81790.1 - 2.6e-07 30.5 0.1 3.8e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel YadA_anchor PF03895.10 EIW81790.1 - 0.059 13.3 4.2 0.083 12.9 2.9 1.3 1 0 0 1 1 1 0 YadA-like C-terminal region HET PF06985.6 EIW81791.1 - 3.4e-19 69.3 0.1 6.6e-19 68.4 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_6 PF12697.2 EIW81792.1 - 5.4e-16 59.1 0.1 1.1e-15 58.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW81792.1 - 0.00049 19.8 0.0 0.0032 17.2 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Transposase_21 PF02992.9 EIW81793.1 - 5.1e-10 38.8 0.0 1.2e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EIW81793.1 - 0.0064 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Angiomotin_C PF12240.3 EIW81795.1 - 0.013 14.9 0.1 0.039 13.4 0.1 1.7 1 0 0 1 1 1 0 Angiomotin C terminal WD40 PF00400.27 EIW81796.1 - 6.7e-76 247.6 31.7 3.3e-07 29.9 0.0 12.3 12 0 0 12 12 12 11 WD domain, G-beta repeat eIF2A PF08662.6 EIW81796.1 - 1.3e-12 47.7 0.8 0.67 9.6 0.0 6.2 3 2 2 6 6 6 5 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EIW81796.1 - 3.6e-06 26.6 6.0 0.018 14.5 1.6 3.8 1 1 1 2 2 2 2 PQQ-like domain Nup160 PF11715.3 EIW81796.1 - 6.2e-06 24.6 12.9 0.26 9.3 0.0 6.9 3 2 5 8 8 8 3 Nucleoporin Nup120/160 PD40 PF07676.7 EIW81796.1 - 0.00011 21.7 1.0 30 4.4 0.0 5.9 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat DUF1513 PF07433.6 EIW81796.1 - 0.00014 20.8 1.4 0.29 10.0 0.0 3.7 3 2 0 4 4 4 2 Protein of unknown function (DUF1513) Nucleoporin_N PF08801.6 EIW81796.1 - 0.0002 20.2 3.2 1.6 7.3 2.2 4.1 2 1 1 3 3 3 2 Nup133 N terminal like BBS2_Mid PF14783.1 EIW81796.1 - 0.0023 17.6 0.0 8.1 6.2 0.0 4.0 4 1 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region Crystall_2 PF09076.5 EIW81796.1 - 0.0026 17.4 0.3 0.0054 16.4 0.2 1.5 1 0 0 1 1 1 1 Beta/Gamma crystallin IKI3 PF04762.7 EIW81796.1 - 0.088 10.6 0.0 4.2 5.0 0.0 3.0 3 0 0 3 3 3 0 IKI3 family Cytochrom_D1 PF02239.11 EIW81796.1 - 0.088 11.0 0.0 1.2 7.3 0.0 2.7 3 0 0 3 3 3 0 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 EIW81796.1 - 0.73 9.2 6.0 4.8 6.5 0.0 4.0 4 0 0 4 4 4 0 Proteasome subunit A N-terminal signature Flavin_Reduct PF01613.13 EIW81797.1 - 7.7e-23 81.0 0.1 1.1e-22 80.5 0.1 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Glyco_hydro_cc PF11790.3 EIW81798.1 - 2.2e-21 76.4 1.4 2.7e-21 76.0 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Lipase_GDSL_2 PF13472.1 EIW81798.1 - 0.071 13.2 0.1 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DPBB_1 PF03330.13 EIW81799.1 - 1.3e-09 37.8 0.1 4e-09 36.3 0.1 1.7 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel F-box-like PF12937.2 EIW81799.1 - 0.00059 19.5 1.2 0.0092 15.6 0.0 2.5 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 EIW81800.1 - 0.0025 17.4 0.0 0.0037 16.9 0.0 1.3 1 0 0 1 1 1 1 F-box-like Pyr_redox_3 PF13738.1 EIW81802.1 - 1e-17 64.9 0.2 7.3e-11 42.5 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW81802.1 - 2e-16 60.4 0.0 2.2e-08 34.2 0.0 2.7 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIW81802.1 - 2.7e-16 58.8 0.0 1.1e-15 56.9 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EIW81802.1 - 7.2e-12 44.8 0.1 1.4e-08 34.0 0.1 3.0 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EIW81802.1 - 3.1e-07 30.6 1.0 0.0034 17.7 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EIW81802.1 - 3.3e-07 30.4 0.1 0.00021 21.4 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EIW81802.1 - 7.2e-07 29.4 0.0 0.00085 19.5 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_binding_3 PF01494.14 EIW81802.1 - 1.9e-05 23.8 0.2 4.4e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EIW81802.1 - 2e-05 24.4 0.8 0.13 12.0 0.0 2.9 3 1 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EIW81802.1 - 9.4e-05 22.3 0.1 0.00027 20.8 0.0 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIW81802.1 - 0.00038 19.4 1.6 0.023 13.5 0.1 2.3 2 1 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.16 EIW81802.1 - 0.00046 19.7 0.6 0.27 10.7 0.0 2.4 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 EIW81802.1 - 0.00054 18.5 1.3 0.0019 16.7 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein 2-Hacid_dh_C PF02826.14 EIW81802.1 - 0.0006 19.0 0.0 0.052 12.6 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EIW81802.1 - 0.0006 18.8 0.1 0.14 11.0 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.19 EIW81802.1 - 0.0009 18.2 1.1 0.38 9.6 0.0 2.8 3 1 0 3 3 3 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EIW81802.1 - 0.0038 16.3 0.0 0.0078 15.3 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EIW81802.1 - 0.006 15.4 4.1 0.61 8.8 0.0 3.3 3 1 0 3 3 3 1 Glucose inhibited division protein A TrkA_N PF02254.13 EIW81802.1 - 0.0077 16.2 0.0 0.26 11.3 0.0 2.6 2 0 0 2 2 2 1 TrkA-N domain Thi4 PF01946.12 EIW81802.1 - 0.0083 15.2 0.1 0.046 12.8 0.0 2.1 2 0 0 2 2 2 1 Thi4 family CPSase_L_chain PF00289.17 EIW81802.1 - 0.036 14.1 0.3 7.3 6.7 0.0 2.8 2 1 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain ThiF PF00899.16 EIW81802.1 - 0.11 12.2 0.8 1.9 8.2 0.1 2.4 2 0 0 2 2 2 0 ThiF family 3HCDH_N PF02737.13 EIW81802.1 - 0.14 11.7 0.0 14 5.2 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F-box-like PF12937.2 EIW81803.1 - 0.00045 19.8 0.0 0.0018 17.9 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIW81804.1 - 1.7e-05 24.4 0.3 0.00014 21.4 0.0 2.5 3 0 0 3 3 3 1 F-box-like PEX-1N PF09262.6 EIW81804.1 - 0.025 14.6 0.0 0.065 13.2 0.0 1.7 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal BUD22 PF09073.5 EIW81804.1 - 0.4 9.6 13.8 0.52 9.3 9.5 1.1 1 0 0 1 1 1 0 BUD22 Cpn60_TCP1 PF00118.19 EIW81805.1 - 6.6e-12 44.7 0.7 7.2e-12 44.6 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Acid_PPase PF12689.2 EIW81806.1 - 9.9e-29 100.1 0.0 1.1e-28 99.9 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 EIW81806.1 - 0.0002 21.6 0.0 0.00027 21.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EIW81807.1 - 7.6e-22 77.7 0.0 2e-21 76.3 0.0 1.7 2 0 0 2 2 2 1 Acid Phosphatase 5_nucleotid_C PF02872.13 EIW81808.1 - 2.6e-23 82.7 0.0 4.3e-23 82.0 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EIW81808.1 - 3.9e-10 39.4 0.3 9.1e-10 38.2 0.2 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase MAP PF03642.8 EIW81808.1 - 0.06 13.5 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 MAP domain Peptidase_A4 PF01828.12 EIW81809.1 - 3.9e-74 248.2 14.5 4.9e-74 247.8 10.0 1.1 1 0 0 1 1 1 1 Peptidase A4 family FAD_binding_8 PF08022.7 EIW81811.1 - 0.034 14.0 0.0 0.097 12.5 0.0 1.7 2 0 0 2 2 2 0 FAD-binding domain Glyco_hydro_61 PF03443.9 EIW81812.1 - 1.7e-60 204.5 0.7 1.9e-60 204.4 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.9 EIW81813.1 - 1.8e-56 191.4 0.2 2e-56 191.2 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 5_nucleotid_C PF02872.13 EIW81814.1 - 7.8e-26 90.9 0.0 1.5e-25 89.9 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EIW81814.1 - 4.2e-06 26.3 0.0 1.2e-05 24.7 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase PGA_cap PF09587.5 EIW81814.1 - 5.9e-05 22.5 0.0 9.9e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Acid_PPase PF12689.2 EIW81815.1 - 9.2e-11 41.6 0.1 3.1e-10 39.9 0.0 1.7 1 1 1 2 2 2 1 Acid Phosphatase Acid_PPase PF12689.2 EIW81816.1 - 8.5e-17 61.2 0.0 1.3e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Acid Phosphatase Pkinase PF00069.20 EIW81816.1 - 0.038 13.1 0.0 5.4 6.0 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain Acid_PPase PF12689.2 EIW81817.1 - 3.1e-30 105.0 0.1 4.6e-30 104.4 0.1 1.3 1 0 0 1 1 1 1 Acid Phosphatase Acid_PPase PF12689.2 EIW81818.1 - 5.6e-13 48.8 0.0 5.8e-13 48.8 0.0 1.1 1 0 0 1 1 1 1 Acid Phosphatase DUF851 PF05867.6 EIW81818.1 - 0.055 12.6 0.5 0.068 12.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF851) ETC_C1_NDUFA4 PF04800.7 EIW81818.1 - 0.056 13.3 0.0 0.097 12.5 0.0 1.5 1 1 0 1 1 1 0 ETC complex I subunit conserved region YqzH PF14164.1 EIW81818.1 - 0.12 12.2 0.4 8.2 6.4 0.0 2.3 1 1 1 2 2 2 0 YqzH-like protein Acid_PPase PF12689.2 EIW81819.1 - 1.2e-18 67.2 0.0 1.4e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase Cyclin_N PF00134.18 EIW81820.1 - 7e-12 45.0 0.1 7.1e-11 41.7 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 EIW81820.1 - 0.00011 21.9 1.5 0.001 18.8 0.2 2.5 2 0 0 2 2 2 1 Transcription factor TFIIB repeat DNA_Packaging PF11053.3 EIW81820.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Terminase DNA packaging enzyme Cpn60_TCP1 PF00118.19 EIW81821.1 - 1.6e-135 452.5 11.6 1.9e-135 452.2 8.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Peptidase_A4 PF01828.12 EIW81822.1 - 9.1e-75 250.2 13.6 1e-74 250.0 9.4 1.0 1 0 0 1 1 1 1 Peptidase A4 family Pyr_redox_3 PF13738.1 EIW81823.1 - 4.9e-23 82.2 0.0 1.2e-21 77.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIW81823.1 - 1.9e-21 75.9 0.0 1.2e-14 53.4 0.0 2.3 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EIW81823.1 - 5.3e-17 62.3 0.0 1.4e-09 38.1 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW81823.1 - 1.8e-11 43.5 0.3 1.7e-09 37.0 0.2 2.9 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 EIW81823.1 - 8.9e-08 32.3 0.2 5.3e-05 23.3 0.0 2.7 3 0 0 3 3 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EIW81823.1 - 4e-06 26.6 0.3 0.0082 15.9 0.0 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 EIW81823.1 - 4.6e-06 26.3 0.3 0.0092 15.5 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 EIW81823.1 - 5.8e-06 25.5 0.1 1.4e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIW81823.1 - 1.2e-05 25.2 0.1 4.8e-05 23.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EIW81823.1 - 5.2e-05 21.8 0.4 0.00026 19.6 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EIW81823.1 - 9.2e-05 22.7 1.9 0.012 15.9 0.1 3.1 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EIW81823.1 - 0.00011 22.4 0.0 0.22 11.8 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding FAD_oxidored PF12831.2 EIW81823.1 - 0.00014 21.0 0.2 0.00024 20.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIW81823.1 - 0.00022 20.2 0.0 0.31 9.9 0.0 2.9 3 0 0 3 3 3 2 Lycopene cyclase protein FAD_binding_2 PF00890.19 EIW81823.1 - 0.0013 17.6 0.2 0.0013 17.6 0.2 2.0 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.19 EIW81823.1 - 0.0022 16.9 5.1 0.22 10.3 0.0 3.0 3 1 0 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.17 EIW81823.1 - 0.0037 16.1 4.6 0.055 12.3 0.0 3.0 3 1 0 3 3 3 1 Glucose inhibited division protein A Thi4 PF01946.12 EIW81823.1 - 0.0064 15.6 0.0 0.023 13.7 0.0 1.9 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.14 EIW81823.1 - 0.0099 15.0 0.0 0.21 10.6 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 EIW81823.1 - 0.088 11.4 0.2 0.19 10.3 0.1 1.5 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.13 EIW81823.1 - 0.098 12.6 0.0 7 6.6 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain F-box-like PF12937.2 EIW81824.1 - 0.033 13.8 0.0 0.083 12.6 0.0 1.7 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.2 EIW81824.1 - 0.42 10.2 2.1 5.9 6.6 0.0 3.7 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) Tet_JBP PF12851.2 EIW81827.1 - 3.3e-15 55.7 0.0 3.9e-15 55.5 0.0 1.0 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily Upf2 PF04050.9 EIW81830.1 - 0.058 13.1 0.4 0.093 12.4 0.3 1.3 1 0 0 1 1 1 0 Up-frameshift suppressor 2 KIAA1430 PF13879.1 EIW81831.1 - 0.037 14.4 0.6 0.13 12.6 0.4 1.9 1 0 0 1 1 1 0 KIAA1430 homologue MscS_porin PF12795.2 EIW81832.1 - 0.096 11.9 0.3 0.19 11.0 0.1 1.4 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain AAA_13 PF13166.1 EIW81832.1 - 0.13 10.7 0.1 0.17 10.2 0.0 1.0 1 0 0 1 1 1 0 AAA domain Zn_clus PF00172.13 EIW81832.1 - 2.8 7.9 11.2 4.8 7.1 7.8 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain HMG_box PF00505.14 EIW81836.1 - 0.13 12.5 3.4 0.092 13.0 0.5 2.2 2 0 0 2 2 2 0 HMG (high mobility group) box HMG_box_2 PF09011.5 EIW81836.1 - 0.26 11.6 5.8 0.2 12.0 2.5 2.1 1 1 1 2 2 2 0 HMG-box domain Tet_JBP PF12851.2 EIW81837.1 - 8.9e-13 47.8 0.1 1.1e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily F-box-like PF12937.2 EIW81837.1 - 0.0071 16.0 0.1 0.015 15.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like Menin PF05053.8 EIW81839.1 - 0.033 12.3 0.4 0.035 12.2 0.3 1.1 1 0 0 1 1 1 0 Menin DUF605 PF04652.11 EIW81839.1 - 0.087 12.2 4.5 0.1 11.9 3.1 1.2 1 0 0 1 1 1 0 Vta1 like Tet_JBP PF12851.2 EIW81840.1 - 3.5e-09 36.1 0.0 3.9e-09 36.0 0.0 1.0 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily GTF2I PF02946.9 EIW81841.1 - 0.095 12.5 0.0 2.4 8.0 0.0 2.9 3 0 0 3 3 3 0 GTF2I-like repeat DUF4078 PF13300.1 EIW81842.1 - 0.22 11.6 2.3 0.29 11.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4078) zf-B_box PF00643.19 EIW81842.1 - 0.62 10.0 7.2 2.1 8.2 5.0 2.0 1 0 0 1 1 1 0 B-box zinc finger p450 PF00067.17 EIW81845.1 - 5.6e-50 170.2 0.0 1e-49 169.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 PPR_2 PF13041.1 EIW81846.1 - 0.00061 19.7 0.3 0.19 11.7 0.0 4.1 4 1 1 5 5 5 2 PPR repeat family NADPH_Ox PF08414.5 EIW81846.1 - 0.27 11.3 2.3 16 5.6 0.2 3.6 3 1 0 3 3 3 0 Respiratory burst NADPH oxidase Pex14_N PF04695.8 EIW81846.1 - 0.39 10.7 5.2 0.85 9.6 0.0 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.20 EIW81847.1 - 8.6e-37 126.6 0.0 1e-36 126.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW81847.1 - 1.8e-34 119.0 0.0 2e-34 118.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW81847.1 - 0.00064 19.5 0.2 0.0032 17.2 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Peptidase_A4 PF01828.12 EIW81849.1 - 1.3e-79 266.1 17.0 1.5e-79 265.9 11.8 1.0 1 0 0 1 1 1 1 Peptidase A4 family Ldh_1_N PF00056.18 EIW81850.1 - 5.5e-45 152.6 0.1 7.7e-45 152.1 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EIW81850.1 - 1.5e-42 145.2 0.0 2.1e-42 144.8 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EIW81850.1 - 0.0033 16.1 0.0 0.0052 15.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIW81850.1 - 0.013 15.5 0.6 0.028 14.4 0.4 1.5 1 0 0 1 1 1 0 NADH(P)-binding Semialdhyde_dh PF01118.19 EIW81850.1 - 0.037 14.3 0.2 0.2 11.9 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EIW81850.1 - 0.054 13.4 0.2 0.12 12.2 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus WD40 PF00400.27 EIW81851.1 - 5.5e-125 403.3 46.5 9.4e-12 44.3 0.0 13.6 14 0 0 14 14 14 13 WD domain, G-beta repeat Nup160 PF11715.3 EIW81851.1 - 1.8e-10 39.6 15.8 0.029 12.5 0.0 8.8 3 2 6 9 9 9 5 Nucleoporin Nup120/160 eIF2A PF08662.6 EIW81851.1 - 5.5e-10 39.2 0.0 0.29 10.8 0.0 5.0 3 2 3 6 6 6 5 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EIW81851.1 - 7.7e-08 32.0 9.6 0.026 13.9 0.1 5.1 3 2 1 4 4 4 3 PQQ-like domain PD40 PF07676.7 EIW81851.1 - 8e-08 31.7 11.6 5.7 6.7 0.0 9.6 10 0 0 10 10 10 1 WD40-like Beta Propeller Repeat Nucleoporin_N PF08801.6 EIW81851.1 - 9.4e-07 27.9 0.8 1.2 7.7 0.1 5.7 2 2 1 6 6 6 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 EIW81851.1 - 0.00017 19.9 0.0 0.27 9.4 0.0 3.6 4 1 0 4 4 4 1 Cytochrome D1 heme domain Proteasome_A_N PF10584.4 EIW81851.1 - 0.00042 19.5 1.5 8.1 5.8 0.0 5.6 5 0 0 5 5 5 1 Proteasome subunit A N-terminal signature PQQ_3 PF13570.1 EIW81851.1 - 0.00074 19.7 10.8 29 5.0 0.0 8.0 6 3 3 9 9 9 0 PQQ-like domain DUF3312 PF11768.3 EIW81851.1 - 0.0046 15.2 0.0 4.2 5.4 0.0 3.5 3 1 1 4 4 4 1 Protein of unknown function (DUF3312) IKI3 PF04762.7 EIW81851.1 - 0.005 14.7 1.7 0.25 9.1 0.0 3.5 3 2 0 3 3 3 1 IKI3 family F-box-like PF12937.2 EIW81853.1 - 5.4e-06 26.0 0.1 1.7e-05 24.4 0.1 1.9 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 EIW81854.1 - 5.7e-110 355.7 45.6 1e-12 47.4 0.1 13.4 13 0 0 13 13 13 13 WD domain, G-beta repeat eIF2A PF08662.6 EIW81854.1 - 2.7e-08 33.7 0.0 0.35 10.5 0.0 5.7 3 2 4 7 7 7 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIW81854.1 - 5.5e-08 31.4 18.3 0.0028 15.8 0.0 7.8 4 2 3 8 8 8 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIW81854.1 - 0.0019 17.0 9.1 0.31 9.7 0.5 5.5 2 2 2 5 5 5 1 Nup133 N terminal like PD40 PF07676.7 EIW81854.1 - 0.0025 17.4 10.6 58 3.5 0.0 7.4 8 0 0 8 8 8 0 WD40-like Beta Propeller Repeat PQQ_3 PF13570.1 EIW81854.1 - 0.003 17.7 2.0 12 6.3 0.0 5.2 5 0 0 5 5 5 1 PQQ-like domain Apc4_WD40 PF12894.2 EIW81854.1 - 0.096 12.2 0.0 9.4 5.8 0.0 3.7 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Arena_nucleocap PF00843.12 EIW81854.1 - 0.16 9.8 0.3 1.5 6.6 0.0 2.6 3 1 1 4 4 4 0 Arenavirus nucleocapsid protein F-box-like PF12937.2 EIW81855.1 - 6.5e-08 32.1 2.5 1.6e-07 30.9 1.7 1.7 1 0 0 1 1 1 1 F-box-like TauD PF02668.11 EIW81856.1 - 5.3e-53 180.3 0.1 6.8e-53 179.9 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF4243 PF14027.1 EIW81857.1 - 3.6e-25 89.1 0.0 4.3e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Asp PF00026.18 EIW81858.1 - 9.3e-20 71.0 0.0 2e-19 70.0 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW81858.1 - 0.027 14.4 0.0 0.073 13.0 0.0 1.7 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal RA PF00788.18 EIW81859.1 - 3.3e-09 37.0 0.0 1.4e-08 35.0 0.0 2.1 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain SH3_1 PF00018.23 EIW81859.1 - 1.7e-05 24.1 0.0 4.8e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EIW81859.1 - 0.00072 19.0 0.0 0.0015 18.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain TauD PF02668.11 EIW81860.1 - 1e-54 185.9 0.2 1.3e-54 185.5 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family F-box-like PF12937.2 EIW81861.1 - 3.5e-07 29.8 0.8 7.5e-07 28.7 0.6 1.6 1 0 0 1 1 1 1 F-box-like DUF4243 PF14027.1 EIW81862.1 - 3e-46 158.3 0.0 3.8e-46 158.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Pcc1 PF09341.5 EIW81862.1 - 0.03 14.3 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 Transcription factor Pcc1 TauD PF02668.11 EIW81863.1 - 1.7e-52 178.6 0.1 2.4e-52 178.1 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family F-box-like PF12937.2 EIW81864.1 - 2.4e-06 27.1 0.9 5.2e-06 26.0 0.6 1.6 1 0 0 1 1 1 1 F-box-like DEAD PF00270.24 EIW81865.1 - 1.4e-11 44.1 0.0 1.9e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase T4SS-DNA_transf PF02534.9 EIW81865.1 - 0.0053 15.3 0.1 0.0078 14.8 0.1 1.5 1 1 0 1 1 1 1 Type IV secretory system Conjugative DNA transfer AAA_34 PF13872.1 EIW81865.1 - 0.0055 15.5 0.0 0.0061 15.3 0.0 1.1 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DUF3689 PF12463.3 EIW81865.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3689) DPBB_1 PF03330.13 EIW81868.1 - 7e-09 35.5 0.1 1e-08 35.0 0.0 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Erg28 PF03694.8 EIW81869.1 - 0.0073 16.3 0.5 0.014 15.3 0.4 1.5 1 0 0 1 1 1 1 Erg28 like protein PRNT PF15174.1 EIW81869.1 - 0.1 12.2 0.1 0.33 10.6 0.0 1.8 2 0 0 2 2 2 0 Prion-related protein testis-specific MobB PF03205.9 EIW81870.1 - 6.3e-09 35.6 0.0 1.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Clp1 PF06807.9 EIW81870.1 - 1.1e-07 31.8 0.0 6.2e-07 29.3 0.0 2.3 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 FtsK_SpoIIIE PF01580.13 EIW81870.1 - 0.00092 18.7 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_14 PF13173.1 EIW81870.1 - 0.024 14.5 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIW81870.1 - 0.075 13.0 0.0 0.26 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain Peptidase_A4 PF01828.12 EIW81871.1 - 1e-79 266.4 16.1 1.2e-79 266.1 11.2 1.1 1 0 0 1 1 1 1 Peptidase A4 family DUF4440 PF14534.1 EIW81871.1 - 0.74 10.0 6.6 0.44 10.7 0.4 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4440) C6 PF01681.12 EIW81871.1 - 1.5 8.9 7.8 3.6 7.7 4.7 2.2 1 1 0 1 1 1 0 C6 domain Transposase_21 PF02992.9 EIW81874.1 - 6.8e-09 35.1 0.0 1.3e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EIW81874.1 - 0.009 15.4 0.1 0.019 14.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) TSC22 PF01166.13 EIW81876.1 - 0.08 12.9 0.1 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 TSC-22/dip/bun family Glyco_hydro_61 PF03443.9 EIW81877.1 - 1.4e-62 211.3 2.0 1.6e-62 211.1 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Peptidase_A4 PF01828.12 EIW81878.1 - 1e-81 272.9 15.6 1.2e-81 272.7 10.8 1.0 1 0 0 1 1 1 1 Peptidase A4 family VCBS PF13517.1 EIW81878.1 - 0.36 11.2 2.9 6.8 7.1 0.2 3.0 2 1 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella HET PF06985.6 EIW81879.1 - 2.1e-16 60.3 8.0 5.3e-15 55.8 1.1 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 EIW81880.1 - 5.5e-46 154.8 9.0 1e-13 51.4 0.1 8.8 7 3 1 8 8 8 6 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EIW81880.1 - 5.3e-34 112.8 3.2 0.0018 18.3 0.0 13.2 14 0 0 14 14 14 7 Ankyrin repeat Ank PF00023.25 EIW81880.1 - 1.3e-30 103.6 13.3 5.2e-05 22.8 0.0 11.2 12 0 0 12 12 12 6 Ankyrin repeat Ank_5 PF13857.1 EIW81880.1 - 3.1e-26 90.7 9.5 0.00014 21.9 0.0 11.2 8 2 4 12 12 12 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIW81880.1 - 1.1e-25 89.5 7.0 3e-05 24.3 0.0 9.5 8 1 1 9 9 9 5 Ankyrin repeats (many copies) Peptidase_A4 PF01828.12 EIW81881.1 - 9.1e-82 273.1 16.3 1e-81 272.9 11.3 1.0 1 0 0 1 1 1 1 Peptidase A4 family VCBS PF13517.1 EIW81881.1 - 1.8 8.9 6.7 15 6.0 0.3 3.0 2 1 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Helitron_like_N PF14214.1 EIW81884.1 - 0.00099 18.8 0.0 0.0012 18.5 0.0 1.1 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PK_C PF02887.11 EIW81884.1 - 0.12 11.9 0.1 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain Helitron_like_N PF14214.1 EIW81885.1 - 0.00036 20.3 0.0 0.0006 19.5 0.0 1.3 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 EIW81886.1 - 1.8e-13 50.1 0.0 2e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EIW81886.1 - 2.7e-10 40.1 0.0 3.7e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW81886.1 - 1.9e-05 24.3 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EIW81886.1 - 0.00028 20.9 0.1 0.00047 20.1 0.1 1.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_11 PF13086.1 EIW81886.1 - 0.0027 17.3 0.0 0.55 9.7 0.0 2.1 1 1 1 2 2 2 2 AAA domain AAA_22 PF13401.1 EIW81886.1 - 0.0075 16.4 0.0 0.014 15.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 EIW81886.1 - 0.0092 15.2 0.0 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EIW81886.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EIW81886.1 - 0.021 14.5 0.0 0.062 13.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EIW81886.1 - 0.023 14.9 0.0 0.041 14.0 0.0 1.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Helicase_RecD PF05127.9 EIW81886.1 - 0.091 12.3 0.1 0.39 10.3 0.1 1.8 1 1 0 1 1 1 0 Helicase Sigma54_activat PF00158.21 EIW81886.1 - 0.094 12.1 0.0 0.13 11.7 0.0 1.3 1 1 0 1 1 1 0 Sigma-54 interaction domain IIGP PF05049.8 EIW81886.1 - 0.1 11.4 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) PIF1 PF05970.9 EIW81887.1 - 0.0009 18.2 0.5 0.0011 18.0 0.4 1.1 1 0 0 1 1 1 1 PIF1-like helicase Rft-1 PF04506.8 EIW81888.1 - 0.12 10.6 0.0 0.12 10.6 0.0 1.0 1 0 0 1 1 1 0 Rft protein SSB PF00436.20 EIW81889.1 - 0.097 12.5 0.1 0.39 10.6 0.0 2.0 2 0 0 2 2 2 0 Single-strand binding protein family SCAMP PF04144.8 EIW81894.1 - 0.0016 18.3 0.4 2.7 7.8 0.0 3.0 2 1 0 2 2 2 2 SCAMP family AIRC PF00731.15 EIW81896.1 - 7.8e-63 210.2 1.6 1.4e-62 209.4 1.1 1.5 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.17 EIW81896.1 - 4.8e-61 205.0 0.0 6.9e-61 204.5 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EIW81896.1 - 5.6e-14 52.2 0.1 9.7e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EIW81896.1 - 7e-06 25.5 0.0 4.3e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.12 EIW81896.1 - 2.5e-05 23.6 0.0 4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 EIW81896.1 - 0.00079 19.3 0.0 0.0023 17.8 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain CoA_binding_2 PF13380.1 EIW81896.1 - 0.013 15.6 0.7 17 5.6 0.0 3.4 2 1 1 3 3 3 0 CoA binding domain ATPgrasp_Ter PF15632.1 EIW81896.1 - 0.014 14.1 0.0 1.5 7.4 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp in the biosynthetic pathway with Ter operon Response_reg PF00072.19 EIW81897.1 - 6e-18 64.8 0.1 1.1e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EIW81897.1 - 2.6e-14 52.8 0.1 7.2e-14 51.4 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EIW81897.1 - 1.1e-09 38.1 0.0 3.3e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Macoilin PF09726.4 EIW81897.1 - 0.55 8.4 4.7 5.4 5.1 0.8 2.8 2 0 0 2 2 2 0 Transmembrane protein Herpes_gE PF02480.11 EIW81898.1 - 0.033 12.4 0.0 0.04 12.1 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1661 PF07877.6 EIW81900.1 - 0.062 12.8 0.2 0.12 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1661) HSP70 PF00012.15 EIW81901.1 - 3.6e-17 61.5 1.1 4.1e-17 61.3 0.8 1.0 1 0 0 1 1 1 1 Hsp70 protein DUF357 PF04010.8 EIW81901.1 - 0.021 14.5 0.1 0.27 10.9 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF357) Spectrin PF00435.16 EIW81901.1 - 0.034 14.4 2.5 0.27 11.5 0.3 2.2 1 1 2 3 3 3 0 Spectrin repeat Tricho_coat PF05892.6 EIW81901.1 - 0.1 11.8 0.3 0.17 11.0 0.2 1.3 1 0 0 1 1 1 0 Trichovirus coat protein Cauli_VI PF01693.11 EIW81902.1 - 0.00014 21.8 0.1 0.00031 20.7 0.1 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin zf-B_box PF00643.19 EIW81903.1 - 0.00086 19.1 7.1 0.0035 17.1 4.9 2.1 1 0 0 1 1 1 1 B-box zinc finger DPBB_1 PF03330.13 EIW81905.1 - 1.2e-11 44.3 0.7 3.1e-11 43.1 0.5 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Cerato-platanin PF07249.7 EIW81905.1 - 0.0027 17.6 0.4 0.0067 16.4 0.2 1.6 1 1 1 2 2 2 1 Cerato-platanin Barwin PF00967.12 EIW81905.1 - 0.013 15.1 0.1 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Barwin family F-box-like PF12937.2 EIW81907.1 - 2.1e-08 33.7 0.9 6.8e-08 32.1 0.6 2.0 1 0 0 1 1 1 1 F-box-like Thaumatin PF00314.12 EIW81908.1 - 7.1e-66 221.7 14.9 8e-66 221.5 10.3 1.0 1 0 0 1 1 1 1 Thaumatin family Rsa3 PF14615.1 EIW81910.1 - 2.2e-11 42.8 0.0 3.2e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Ribosome-assembly protein 3 TFIIF_alpha PF05793.7 EIW81910.1 - 0.019 13.3 14.9 0.029 12.7 10.3 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 EIW81910.1 - 0.099 10.5 3.9 0.12 10.2 2.7 1.1 1 0 0 1 1 1 0 Nop14-like family Cwf_Cwc_15 PF04889.7 EIW81910.1 - 0.12 12.0 13.8 0.18 11.4 9.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1675 PF07897.6 EIW81910.1 - 0.39 10.5 6.2 0.51 10.1 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) Daxx PF03344.10 EIW81910.1 - 1.4 7.2 10.6 1.8 6.9 7.3 1.1 1 0 0 1 1 1 0 Daxx Family DUF605 PF04652.11 EIW81910.1 - 6.4 6.0 23.6 8 5.7 16.4 1.1 1 0 0 1 1 1 0 Vta1 like Choline_transpo PF04515.7 EIW81912.1 - 1.1e-87 293.9 16.0 1.1e-87 293.9 11.1 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter DPBB_1 PF03330.13 EIW81913.1 - 7.1e-10 38.7 0.7 3.3e-09 36.6 0.5 1.9 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIW81913.1 - 0.028 14.0 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Barwin family DPBB_1 PF03330.13 EIW81914.1 - 1.1e-09 38.1 0.4 1.7e-09 37.5 0.3 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIW81914.1 - 0.0061 16.2 0.1 0.0099 15.5 0.1 1.4 1 1 0 1 1 1 1 Barwin family Cerato-platanin PF07249.7 EIW81914.1 - 0.086 12.8 0.1 0.14 12.1 0.1 1.4 1 0 0 1 1 1 0 Cerato-platanin Oxidored_q1 PF00361.15 EIW81916.1 - 4.5 6.4 11.8 0.23 10.6 2.5 2.0 2 0 0 2 2 2 0 NADH-Ubiquinone/plastoquinone (complex I), various chains Bac_rhamnosid PF05592.6 EIW81919.1 - 8.8e-27 93.4 3.2 1.1e-24 86.5 2.4 2.9 2 1 0 2 2 2 1 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 EIW81919.1 - 2.2e-10 39.8 2.1 3.4e-10 39.1 1.5 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Trehalase PF01204.13 EIW81919.1 - 0.00033 19.4 0.6 0.00047 18.9 0.4 1.1 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 EIW81919.1 - 0.037 12.7 0.5 0.1 11.2 0.3 1.7 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase F_bP_aldolase PF01116.15 EIW81920.1 - 5.9e-99 330.7 0.0 6.7e-99 330.6 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II p450 PF00067.17 EIW81921.1 - 2.3e-65 220.9 0.0 3.3e-65 220.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 UPRTase PF14681.1 EIW81924.1 - 2.3e-77 258.8 0.0 2.8e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EIW81924.1 - 2e-06 27.5 0.0 2.8e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain CoA_binding_2 PF13380.1 EIW81924.1 - 0.068 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 CoA binding domain HSL_N PF06350.7 EIW81926.1 - 0.11 11.5 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Hormone-sensitive lipase (HSL) N-terminus APG6 PF04111.7 EIW81927.1 - 0.0008 18.5 11.3 0.0012 17.9 7.8 1.2 1 0 0 1 1 1 1 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EIW81927.1 - 0.0025 17.7 17.5 0.0062 16.3 6.8 2.2 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.6 EIW81927.1 - 0.0082 15.9 12.3 0.022 14.6 8.5 1.6 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) PilJ PF13675.1 EIW81927.1 - 0.048 13.9 2.1 0.1 12.9 1.5 1.6 1 0 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term IncA PF04156.9 EIW81927.1 - 0.061 12.9 11.9 0.099 12.2 8.2 1.3 1 0 0 1 1 1 0 IncA protein Lumazine_bd PF12870.2 EIW81927.1 - 0.14 12.1 4.2 0.081 12.9 1.3 1.7 2 0 0 2 2 2 0 Lumazine-binding domain V_ATPase_I PF01496.14 EIW81927.1 - 0.15 9.8 6.2 0.21 9.4 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_13 PF13166.1 EIW81927.1 - 0.17 10.3 6.2 0.21 10.0 4.3 1.1 1 0 0 1 1 1 0 AAA domain Cwf_Cwc_15 PF04889.7 EIW81927.1 - 0.18 11.4 8.5 0.3 10.7 5.9 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF2828 PF11443.3 EIW81927.1 - 0.19 9.9 5.0 0.25 9.5 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF3435 PF11917.3 EIW81927.1 - 0.24 10.0 6.9 0.34 9.5 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3435) DUF342 PF03961.8 EIW81927.1 - 0.32 9.3 5.1 0.46 8.8 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3287 PF11690.3 EIW81927.1 - 0.33 11.0 3.0 0.5 10.4 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) Spc24 PF08286.6 EIW81927.1 - 0.85 9.3 12.3 5.1 6.8 4.2 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 YscO PF07321.7 EIW81927.1 - 1.7 8.4 15.6 0.2 11.4 6.7 2.1 1 1 1 2 2 2 0 Type III secretion protein YscO GAS PF13851.1 EIW81927.1 - 3.2 6.9 14.8 22 4.1 10.5 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Med4 PF10018.4 EIW81927.1 - 4.6 6.5 9.8 14 5.0 6.8 2.0 1 1 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Macoilin PF09726.4 EIW81927.1 - 6.1 4.9 9.8 8.3 4.5 6.8 1.1 1 0 0 1 1 1 0 Transmembrane protein ABC_tran PF00005.22 EIW81928.1 - 0.013 15.7 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EIW81928.1 - 0.013 14.9 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EIW81928.1 - 0.015 15.2 0.2 0.027 14.4 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain PRK PF00485.13 EIW81928.1 - 0.029 13.9 0.1 0.038 13.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.1 EIW81928.1 - 0.034 14.2 0.0 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EIW81928.1 - 0.038 13.2 0.0 0.055 12.7 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein APS_kinase PF01583.15 EIW81928.1 - 0.044 13.4 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_5 PF07728.9 EIW81928.1 - 0.055 13.1 0.0 0.45 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MobB PF03205.9 EIW81928.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B A_thal_3526 PF09713.5 EIW81930.1 - 0.041 14.0 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 Plant protein 1589 of unknown function (A_thal_3526) p450 PF00067.17 EIW81931.1 - 1.6e-66 224.7 0.0 2.4e-66 224.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_92 PF07971.7 EIW81933.1 - 3e-83 280.1 0.2 3.6e-83 279.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92 PF07971.7 EIW81934.1 - 2e-61 208.2 0.8 2.5e-61 207.8 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Actin PF00022.14 EIW81935.1 - 7.6e-101 337.3 0.0 1.1e-100 336.9 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EIW81935.1 - 0.00026 19.7 0.0 0.026 13.1 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein TMEM190 PF15431.1 EIW81935.1 - 0.15 11.9 0.3 0.26 11.1 0.2 1.3 1 0 0 1 1 1 0 Transmembrane protein 190 Glyco_hydro_43 PF04616.9 EIW81936.1 - 8.2e-35 120.2 0.0 9.6e-35 120.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 BNR PF02012.15 EIW81936.1 - 0.069 13.0 1.6 3.3 7.9 0.1 3.2 2 0 0 2 2 2 0 BNR/Asp-box repeat CoxIIa PF08113.6 EIW81936.1 - 4.2 7.1 5.6 1.1 9.0 0.2 2.5 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IIa family Peptidase_M1 PF01433.15 EIW81938.1 - 2e-106 356.3 0.0 1.3e-68 231.8 0.0 2.5 1 1 1 2 2 2 2 Peptidase family M1 ERAP1_C PF11838.3 EIW81938.1 - 5e-47 160.7 0.1 7.7e-47 160.1 0.1 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EIW81938.1 - 2.1e-13 50.4 0.0 6.1e-13 48.9 0.0 1.8 1 0 0 1 1 1 1 Peptidase MA superfamily EMG1 PF03587.9 EIW81939.1 - 9.7e-76 253.5 0.0 1.1e-75 253.3 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Malectin_like PF12819.2 EIW81941.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate-binding protein of the ER T4_deiodinase PF00837.12 EIW81942.1 - 0.095 11.6 0.0 0.11 11.4 0.0 1.1 1 0 0 1 1 1 0 Iodothyronine deiodinase F-box-like PF12937.2 EIW81943.1 - 2e-10 40.2 6.3 4.3e-10 39.1 4.3 1.6 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EIW81943.1 - 0.0093 15.7 0.6 0.063 13.0 0.0 2.7 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.2 EIW81943.1 - 0.025 14.2 1.6 0.59 9.8 0.0 3.0 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) CRAL_TRIO PF00650.15 EIW81944.1 - 4e-36 123.9 0.0 5.9e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EIW81944.1 - 1.1e-12 47.8 0.7 2.9e-12 46.5 0.5 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EIW81944.1 - 0.027 14.3 0.0 0.058 13.2 0.0 1.5 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain PGM_PMM_IV PF00408.15 EIW81945.1 - 0.078 12.9 0.1 1.2 9.1 0.0 2.7 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain p450 PF00067.17 EIW81948.1 - 3.3e-69 233.5 0.0 5.4e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW81950.1 - 7.9e-62 209.2 0.0 1.3e-61 208.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF4620 PF15399.1 EIW81950.1 - 0.76 9.9 3.7 0.26 11.4 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4620) Ifi-6-16 PF06140.8 EIW81951.1 - 0.0092 15.7 15.5 0.012 15.4 0.3 4.0 4 0 0 4 4 4 2 Interferon-induced 6-16 family DMPK_coil PF08826.5 EIW81951.1 - 0.11 12.3 0.2 0.45 10.4 0.2 2.0 1 0 0 1 1 1 0 DMPK coiled coil domain like DUF972 PF06156.8 EIW81951.1 - 0.14 12.4 0.8 3.2 8.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF972) MerR-DNA-bind PF09278.6 EIW81951.1 - 0.21 12.0 3.6 1.1 9.6 0.2 2.9 2 0 0 2 2 2 0 MerR, DNA binding CENP-Q PF13094.1 EIW81951.1 - 0.41 10.6 2.8 0.23 11.4 0.2 1.9 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit WD40 PF00400.27 EIW81952.1 - 7.8e-126 406.0 52.0 1.8e-12 46.5 0.2 13.1 13 0 0 13 13 13 13 WD domain, G-beta repeat eIF2A PF08662.6 EIW81952.1 - 9.7e-10 38.4 0.0 0.0074 16.0 0.0 4.6 3 2 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIW81952.1 - 1.1e-08 33.7 9.2 0.041 12.0 0.0 6.6 4 3 2 6 6 6 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EIW81952.1 - 1.1e-07 31.6 3.0 0.044 13.2 0.0 4.1 3 2 1 4 4 4 2 PQQ-like domain PD40 PF07676.7 EIW81952.1 - 2.2e-07 30.4 5.1 2.7 7.7 0.0 8.2 9 0 0 9 9 9 3 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 EIW81952.1 - 6.1e-06 25.8 2.8 5.6 6.2 0.0 5.3 3 2 1 5 5 5 3 Lipoprotein LpqB beta-propeller domain XK-related PF09815.4 EIW81953.1 - 0.15 10.9 3.0 0.32 9.9 0.6 2.1 1 1 1 2 2 2 0 XK-related protein p450 PF00067.17 EIW81954.1 - 7e-66 222.6 0.0 1.3e-65 221.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW81955.1 - 8.8e-69 232.1 0.0 1.2e-68 231.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RCR PF12273.3 EIW81957.1 - 0.26 11.8 5.1 1.1 9.8 3.5 2.0 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red MLANA PF14991.1 EIW81959.1 - 0.074 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein melan-A DUF966 PF06136.8 EIW81959.1 - 0.14 11.5 2.9 0.18 11.1 2.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF4381 PF14316.1 EIW81960.1 - 0.0053 16.8 1.0 0.022 14.8 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) DUF3366 PF11846.3 EIW81960.1 - 0.0065 16.3 0.1 0.01 15.6 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3366) Pescadillo_N PF06732.6 EIW81960.1 - 0.012 14.9 0.1 0.017 14.4 0.1 1.1 1 0 0 1 1 1 0 Pescadillo N-terminus TMEM51 PF15345.1 EIW81960.1 - 0.027 14.1 0.6 0.052 13.2 0.3 1.6 1 1 0 1 1 1 0 Transmembrane protein 51 FtsL PF04999.8 EIW81960.1 - 0.036 13.7 0.7 0.063 13.0 0.5 1.3 1 0 0 1 1 1 0 Cell division protein FtsL Ctr PF04145.10 EIW81960.1 - 0.12 12.4 0.5 0.23 11.4 0.3 1.7 1 1 0 1 1 1 0 Ctr copper transporter family Actin PF00022.14 EIW81961.1 - 1.5e-299 991.6 0.0 2.1e-149 497.2 0.0 2.0 2 0 0 2 2 2 2 Actin ESSS PF10183.4 EIW81961.1 - 3.6e-05 24.0 0.0 0.52 10.7 0.0 2.6 2 0 0 2 2 2 2 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Phosphodiest PF01663.17 EIW81961.1 - 0.0015 17.8 0.1 1.5 8.0 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF3989 PF13150.1 EIW81961.1 - 0.084 12.3 0.1 12 5.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) Pyr_excise PF03013.9 EIW81961.1 - 0.14 11.9 0.2 21 4.9 0.0 2.4 2 0 0 2 2 2 0 Pyrimidine dimer DNA glycosylase p450 PF00067.17 EIW81963.1 - 2.6e-70 237.2 0.0 4.1e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 EIW81965.1 - 1.8e-16 59.3 4.8 0.00014 21.5 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF912 PF06024.7 EIW81965.1 - 0.0051 16.8 0.0 0.0087 16.0 0.0 1.3 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Pox_F17 PF04767.7 EIW81965.1 - 0.055 13.7 0.5 0.097 12.9 0.4 1.3 1 0 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein BBS2_Mid PF14783.1 EIW81965.1 - 0.077 12.7 0.0 5.5 6.7 0.0 2.7 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Oxidored-like PF09791.4 EIW81965.1 - 0.098 12.1 0.2 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Oxidoreductase-like protein, N-terminal ABC_tran PF00005.22 EIW81967.1 - 1.5e-06 28.5 0.0 1.8e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EIW81967.1 - 0.0026 17.0 0.0 0.0029 16.8 0.0 1.0 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIW81967.1 - 0.052 13.4 0.1 0.054 13.4 0.0 1.0 1 0 0 1 1 1 0 AAA domain F-box PF00646.28 EIW81968.1 - 9.8e-05 21.9 0.0 0.00036 20.0 0.0 2.0 2 0 0 2 2 2 1 F-box domain KOW PF00467.24 EIW81969.1 - 2e-05 24.1 1.8 0.11 12.2 0.4 4.2 4 0 0 4 4 4 2 KOW motif Collagen PF01391.13 EIW81969.1 - 0.0089 15.5 6.6 0.027 14.0 4.6 1.7 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Daxx PF03344.10 EIW81969.1 - 7.1 4.9 7.5 11 4.4 5.2 1.1 1 0 0 1 1 1 0 Daxx Family Tox-MPTase2 PF15638.1 EIW81971.1 - 0.12 11.8 0.0 0.33 10.4 0.0 1.7 1 1 0 1 1 1 0 Metallopeptidase toxin 2 Pkinase PF00069.20 EIW81973.1 - 1.1e-08 34.5 0.0 2e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EIW81973.1 - 1.4e-07 31.4 0.1 5.8e-07 29.4 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIW81973.1 - 0.0093 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EIW81973.1 - 0.016 14.5 0.0 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Pkinase_Tyr PF07714.12 EIW81973.1 - 0.052 12.6 0.0 0.058 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DAG1 PF05454.6 EIW81974.1 - 0.0043 16.2 0.0 0.0072 15.5 0.0 1.3 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) VWA_2 PF13519.1 EIW81975.1 - 8.3e-11 42.2 1.6 1.4e-10 41.5 0.1 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain UIM PF02809.15 EIW81975.1 - 4e-10 38.3 13.8 0.00076 18.8 1.2 3.8 3 0 0 3 3 3 3 Ubiquitin interaction motif Ssl1 PF04056.9 EIW81975.1 - 1.8e-08 34.1 0.0 2.8e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like Abhydrolase_5 PF12695.2 EIW81975.1 - 0.054 13.2 0.4 0.16 11.7 0.1 1.9 1 1 1 2 2 2 0 Alpha/beta hydrolase family Lipase_GDSL_2 PF13472.1 EIW81976.1 - 8.1e-22 78.2 2.6 1.1e-20 74.4 1.8 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EIW81976.1 - 1.3e-15 57.9 0.0 1.4e-14 54.4 0.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SARG PF15385.1 EIW81976.1 - 0.46 9.7 0.1 0.46 9.7 0.0 2.1 2 0 0 2 2 2 0 Specifically androgen-regulated gene protein UNC-79 PF14776.1 EIW81977.1 - 0.09 11.1 0.0 0.094 11.0 0.0 1.0 1 0 0 1 1 1 0 Cation-channel complex subunit UNC-79 DUF2872 PF11071.3 EIW81978.1 - 0.064 13.1 0.1 0.16 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2872) NDUF_B7 PF05676.8 EIW81981.1 - 1.8e-25 88.0 2.1 2.2e-25 87.8 1.5 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EIW81981.1 - 4.3e-05 23.1 3.1 6.1e-05 22.7 2.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like SCO1-SenC PF02630.9 EIW81982.1 - 1.6e-52 177.6 0.0 2e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EIW81982.1 - 0.00027 20.5 0.0 0.0018 17.9 0.0 2.2 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EIW81982.1 - 0.022 14.8 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like CGI-121 PF08617.5 EIW81984.1 - 9.3e-35 119.6 0.2 1e-34 119.5 0.2 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 PMC2NT PF08066.7 EIW81986.1 - 0.061 13.6 1.5 0.19 12.0 1.0 1.9 1 0 0 1 1 1 0 PMC2NT (NUC016) domain DUF3864 PF12980.2 EIW81987.1 - 0.075 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3864) Thioredoxin PF00085.15 EIW81988.1 - 1e-46 156.8 0.1 1.1e-23 82.8 0.1 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 EIW81988.1 - 6.1e-07 29.4 0.0 0.00013 21.7 0.0 3.1 2 1 1 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EIW81988.1 - 8.9e-06 25.7 0.1 0.037 14.1 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EIW81988.1 - 0.00012 22.2 1.9 0.012 15.8 0.2 3.2 2 2 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EIW81988.1 - 0.001 19.0 0.9 0.016 15.1 0.1 3.0 3 0 0 3 3 3 1 Thioredoxin-like zf-C2H2_4 PF13894.1 EIW81988.1 - 0.016 15.5 4.6 1.3 9.5 0.7 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger Thioredoxin_4 PF13462.1 EIW81988.1 - 0.02 14.9 1.4 0.057 13.4 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin zf-C2H2 PF00096.21 EIW81988.1 - 0.058 13.7 2.6 5.7 7.4 0.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type PPR_2 PF13041.1 EIW81989.1 - 1.5e-49 165.7 3.1 2.1e-11 43.6 0.0 14.0 13 2 2 15 15 15 9 PPR repeat family PPR PF01535.15 EIW81989.1 - 2.5e-37 124.2 10.1 9.4e-05 22.1 0.0 14.0 15 0 0 15 15 15 6 PPR repeat PPR_3 PF13812.1 EIW81989.1 - 6.7e-34 113.3 27.7 0.0002 21.3 0.0 15.4 18 0 0 18 18 18 8 Pentatricopeptide repeat domain PPR_1 PF12854.2 EIW81989.1 - 5e-32 109.0 0.1 9.9e-06 24.9 0.0 12.4 13 0 0 13 13 13 5 PPR repeat TPR_14 PF13428.1 EIW81989.1 - 2.3e-11 43.2 18.8 0.068 13.8 0.0 11.0 11 0 0 11 11 11 3 Tetratricopeptide repeat TPR_6 PF13174.1 EIW81989.1 - 0.0037 17.6 3.9 39 5.0 0.0 6.7 6 0 0 6 6 6 0 Tetratricopeptide repeat RPM2 PF08579.6 EIW81989.1 - 0.024 14.7 0.1 1.9 8.6 0.0 3.3 3 0 0 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.2 EIW81989.1 - 0.14 11.5 0.2 73 2.7 0.0 4.3 5 0 0 5 5 5 0 Mitochondrial ATPase expression DUF1186 PF06685.6 EIW81989.1 - 0.21 10.7 0.0 0.82 8.7 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1186) CDC45 PF02724.9 EIW81990.1 - 0.0035 15.4 7.8 0.0051 14.9 5.4 1.1 1 0 0 1 1 1 1 CDC45-like protein CobT PF06213.7 EIW81990.1 - 0.049 12.7 4.2 0.09 11.9 2.9 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.7 EIW81990.1 - 0.064 11.1 6.3 0.11 10.4 4.4 1.3 1 0 0 1 1 1 0 Nop14-like family Na_trans_assoc PF06512.8 EIW81990.1 - 0.91 9.4 6.0 2 8.3 4.1 1.5 1 0 0 1 1 1 0 Sodium ion transport-associated FAM176 PF14851.1 EIW81990.1 - 2.7 7.6 4.8 8.4 6.0 3.3 1.8 1 0 0 1 1 1 0 FAM176 family DUF515 PF04415.7 EIW81990.1 - 4.6 5.3 9.3 8.9 4.4 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF515) SpoIIIAH PF12685.2 EIW81990.1 - 6.7 6.1 8.4 14 5.0 5.8 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein Sec63 PF02889.11 EIW81991.1 - 6.1e-31 107.8 0.0 9e-31 107.2 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EIW81991.1 - 1.7e-16 59.7 0.0 3.8e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain DUF983 PF06170.7 EIW81991.1 - 0.038 14.0 0.4 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Tctex-1 PF03645.8 EIW81991.1 - 0.041 13.7 0.0 0.092 12.5 0.0 1.6 1 0 0 1 1 1 0 Tctex-1 family PNPase PF03726.9 EIW81991.1 - 0.083 13.1 2.2 1 9.6 0.1 3.3 4 0 0 4 4 4 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain DUF4218 PF13960.1 EIW81993.1 - 0.002 17.5 0.0 0.0039 16.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DUF2719 PF10891.3 EIW81993.1 - 0.073 12.7 0.1 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2719) DEAD PF00270.24 EIW81995.1 - 3e-07 30.0 0.1 3.3e-07 29.9 0.1 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EIW81995.1 - 0.072 11.9 0.0 0.072 11.9 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF3825 PF12873.2 EIW81995.1 - 0.09 11.9 0.1 0.097 11.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3825) DUF3138 PF11336.3 EIW81997.1 - 0.0099 14.0 0.1 0.014 13.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3138) Antimicrobial19 PF08225.6 EIW81997.1 - 0.012 15.0 0.2 0.012 15.0 0.1 1.8 2 0 0 2 2 2 0 Pseudin antimicrobial peptide DivIC PF04977.10 EIW81997.1 - 2.1 7.9 5.0 0.34 10.4 0.4 1.8 2 0 0 2 2 2 0 Septum formation initiator DDE_1 PF03184.14 EIW81998.1 - 6.5e-23 81.0 0.0 1e-22 80.3 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIW81998.1 - 3.7e-05 23.5 0.1 6.2e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIW81998.1 - 0.067 13.0 0.0 0.28 11.0 0.0 2.0 2 0 0 2 2 2 0 Tc5 transposase DNA-binding domain DUF1676 PF07898.8 EIW81999.1 - 0.086 13.1 0.7 0.39 11.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1676) Transposase_21 PF02992.9 EIW82000.1 - 1.4e-07 30.8 0.0 2.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 Rox3 PF08633.5 EIW82004.1 - 0.055 13.7 6.5 0.11 12.8 0.5 2.3 2 0 0 2 2 2 0 Rox3 mediator complex subunit Glyco_transf_15 PF01793.11 EIW82006.1 - 0.043 12.7 0.2 0.052 12.4 0.1 1.1 1 0 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase zf-Di19 PF05605.7 EIW82007.1 - 0.0065 16.5 3.1 0.007 16.4 0.3 2.2 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding Mito_fiss_reg PF05308.6 EIW82007.1 - 0.39 10.0 1.8 0.59 9.4 1.2 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator zf-C2H2 PF00096.21 EIW82007.1 - 3.1 8.3 8.3 0.15 12.4 1.1 2.4 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF4218 PF13960.1 EIW82014.1 - 0.0062 15.9 0.0 0.016 14.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) DDRGK PF09756.4 EIW82014.1 - 0.4 10.0 14.4 1 8.7 10.0 1.7 1 0 0 1 1 1 0 DDRGK domain NARP1 PF12569.3 EIW82014.1 - 3.6 6.2 13.1 7.8 5.1 9.1 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4218 PF13960.1 EIW82015.1 - 8.4e-06 25.2 0.1 1.5e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Transposase_21 PF02992.9 EIW82015.1 - 0.00012 21.2 0.0 0.00019 20.5 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 Syntaxin PF00804.20 EIW82021.1 - 0.17 12.0 5.3 1.6 8.9 3.7 2.0 1 1 0 1 1 1 0 Syntaxin DUF2408 PF10303.4 EIW82026.1 - 0.085 12.9 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) FliT PF05400.8 EIW82028.1 - 0.16 12.3 6.9 0.3 11.5 4.8 1.4 1 0 0 1 1 1 0 Flagellar protein FliT Phage_min_tail PF05939.8 EIW82031.1 - 0.068 13.1 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Phage minor tail protein DUF2433 PF10360.4 EIW82035.1 - 6.4e-33 113.8 0.0 1.3e-32 112.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) RRM_6 PF14259.1 EIW82035.1 - 8.9e-05 22.3 0.0 0.00018 21.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIW82035.1 - 0.0033 17.0 0.0 0.0079 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos_2 PF12850.2 EIW82035.1 - 0.065 13.0 0.0 0.12 12.1 0.0 1.6 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EIW82035.1 - 0.079 12.3 0.0 0.23 10.8 0.0 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase Acyl-CoA_dh_1 PF00441.19 EIW82036.1 - 9.8e-44 149.0 2.9 1.4e-43 148.5 2.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EIW82036.1 - 2e-27 95.9 0.3 7.6e-27 94.1 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EIW82036.1 - 7.5e-21 74.7 1.0 1.2e-20 74.1 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EIW82036.1 - 7.5e-20 70.1 0.0 1.5e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 EIW82036.1 - 0.065 13.5 0.0 0.15 12.3 0.0 1.7 1 1 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal CYTL1 PF15153.1 EIW82036.1 - 0.089 12.4 0.0 0.72 9.5 0.0 2.1 2 0 0 2 2 2 0 Cytokine-like protein 1 TatD_DNase PF01026.16 EIW82037.1 - 3.7e-24 85.3 0.0 5e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase RNA_pol_Rpb1_5 PF04998.12 EIW82038.1 - 7e-91 304.3 0.0 1e-90 303.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EIW82038.1 - 2.4e-85 286.7 0.0 3.6e-85 286.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EIW82038.1 - 2e-67 226.2 0.0 5.2e-67 224.9 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EIW82038.1 - 5.2e-38 130.2 0.0 1.4e-36 125.5 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EIW82038.1 - 2.9e-33 113.8 0.0 6.1e-33 112.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Zn_Tnp_IS1 PF03811.8 EIW82038.1 - 0.004 16.6 0.0 0.0095 15.4 0.0 1.6 1 0 0 1 1 1 1 InsA N-terminal domain DUF2786 PF10979.3 EIW82038.1 - 0.006 16.2 0.1 0.015 15.0 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2786) Proteasome PF00227.21 EIW82039.1 - 7.7e-44 149.2 0.3 4.5e-43 146.7 0.2 1.9 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIW82039.1 - 3.4e-15 55.0 0.4 6.2e-15 54.2 0.3 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Hist_deacetyl PF00850.14 EIW82040.1 - 6.1e-77 258.9 0.0 1.3e-76 257.8 0.0 1.5 2 0 0 2 2 2 1 Histone deacetylase domain GDI PF00996.13 EIW82041.1 - 4.8e-48 163.5 0.0 9.4e-48 162.6 0.0 1.5 1 1 0 1 1 1 1 GDP dissociation inhibitor LytR_C PF13399.1 EIW82041.1 - 0.16 12.3 0.1 12 6.3 0.0 2.4 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator RRM_1 PF00076.17 EIW82042.1 - 3.7e-42 141.7 0.0 1.8e-20 72.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW82042.1 - 1.1e-32 111.8 0.0 4e-17 61.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW82042.1 - 7.1e-21 73.8 0.0 7.1e-11 41.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ric8 PF10165.4 EIW82043.1 - 1.4e-69 235.1 0.0 6.4e-69 232.8 0.0 1.8 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Med10 PF09748.4 EIW82044.1 - 1.1e-16 60.7 0.1 1.4e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex PIN_4 PF13638.1 EIW82044.1 - 0.11 12.6 0.1 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 PIN domain ABC_membrane PF00664.18 EIW82045.1 - 8.5e-66 222.1 35.7 1.9e-37 129.1 8.6 3.1 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIW82045.1 - 1.6e-55 187.1 0.0 9.6e-32 110.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EIW82045.1 - 1.7e-07 30.6 4.8 0.018 14.3 0.0 4.1 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EIW82045.1 - 2.3e-07 30.9 0.6 0.0018 18.2 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EIW82045.1 - 1.5e-06 28.1 0.2 0.09 12.7 0.1 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EIW82045.1 - 1.7e-05 24.2 0.3 0.066 12.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EIW82045.1 - 2.6e-05 24.3 2.7 0.8 9.6 0.0 4.0 3 1 0 3 3 3 2 AAA domain Miro PF08477.8 EIW82045.1 - 3.5e-05 24.2 0.1 0.53 10.7 0.1 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_25 PF13481.1 EIW82045.1 - 0.00019 20.9 0.0 0.19 11.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EIW82045.1 - 0.00026 20.1 0.3 0.12 11.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 T2SE PF00437.15 EIW82045.1 - 0.0017 17.3 0.0 1.6 7.5 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein Dynamin_N PF00350.18 EIW82045.1 - 0.0034 17.2 1.9 0.43 10.3 0.1 2.3 2 0 0 2 2 2 1 Dynamin family ArgK PF03308.11 EIW82045.1 - 0.004 15.9 0.2 0.35 9.5 0.1 2.2 2 0 0 2 2 2 1 ArgK protein AAA_23 PF13476.1 EIW82045.1 - 0.005 17.1 0.6 1.3 9.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain ABC_ATPase PF09818.4 EIW82045.1 - 0.0079 14.8 0.0 0.0079 14.8 0.0 2.0 3 0 0 3 3 3 1 Predicted ATPase of the ABC class DUF87 PF01935.12 EIW82045.1 - 0.0082 15.9 3.5 0.51 10.1 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function DUF87 Zeta_toxin PF06414.7 EIW82045.1 - 0.011 14.8 0.1 2.1 7.4 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.1 EIW82045.1 - 0.018 14.6 0.4 5.8 6.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 EIW82045.1 - 0.034 13.6 0.5 1.6 8.1 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EIW82045.1 - 0.11 11.9 0.0 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 EIW82045.1 - 0.12 12.0 0.9 1.4 8.5 0.0 2.8 3 0 0 3 3 3 0 Archaeal ATPase AAA_10 PF12846.2 EIW82045.1 - 0.27 10.6 2.0 9.4 5.5 0.1 2.7 3 0 0 3 3 3 0 AAA-like domain AAA_22 PF13401.1 EIW82045.1 - 0.47 10.6 1.9 23 5.1 0.4 3.6 2 1 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EIW82045.1 - 0.6 8.9 1.0 37 3.0 0.4 3.0 2 1 0 2 2 2 0 NB-ARC domain GTP_EFTU PF00009.22 EIW82047.1 - 5.5e-47 159.6 0.0 6.8e-47 159.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EIW82047.1 - 2e-25 88.8 0.0 5.1e-25 87.5 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EIW82047.1 - 2.4e-08 33.9 0.5 1.2e-07 31.6 0.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIW82047.1 - 7.8e-06 25.8 0.0 1.8e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIW82047.1 - 0.011 16.2 0.0 0.057 13.9 0.0 2.3 2 1 0 2 2 2 0 Miro-like protein PduV-EutP PF10662.4 EIW82047.1 - 0.15 11.5 0.3 22 4.4 0.0 2.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MFS_1 PF07690.11 EIW82048.1 - 7.9e-40 136.6 26.6 7.9e-40 136.6 18.4 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_2 PF00703.16 EIW82049.1 - 1.1e-07 32.2 0.4 4e-07 30.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EIW82049.1 - 0.00013 21.5 0.1 0.00025 20.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EIW82049.1 - 0.00031 19.7 0.0 0.00058 18.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain FlgD_ig PF13860.1 EIW82049.1 - 0.045 13.4 0.2 0.17 11.6 0.1 1.9 2 0 0 2 2 2 0 FlgD Ig-like domain Ras PF00071.17 EIW82050.1 - 2e-47 160.5 0.3 2.3e-47 160.3 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW82050.1 - 2.8e-17 63.2 0.1 4.3e-17 62.7 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIW82050.1 - 1.1e-05 25.3 0.0 2e-05 24.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIW82050.1 - 3.4e-05 23.3 0.2 0.00034 20.0 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EIW82050.1 - 0.00029 20.1 0.0 0.00034 19.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Arch_ATPase PF01637.13 EIW82050.1 - 0.00031 20.5 0.1 0.00049 19.8 0.1 1.6 1 1 0 1 1 1 1 Archaeal ATPase SRPRB PF09439.5 EIW82050.1 - 0.00094 18.4 0.0 0.0013 17.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EIW82050.1 - 0.005 16.7 0.0 0.006 16.4 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EIW82050.1 - 0.025 13.7 0.1 0.081 12.1 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 FeoB_N PF02421.13 EIW82050.1 - 0.061 12.5 0.0 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 Ferrous iron transport protein B Dynamin_N PF00350.18 EIW82050.1 - 0.068 12.9 0.3 0.095 12.5 0.2 1.6 1 1 0 1 1 1 0 Dynamin family AA_permease_2 PF13520.1 EIW82051.1 - 8.7e-78 261.7 36.5 1.1e-77 261.3 25.3 1.1 1 0 0 1 1 1 1 Amino acid permease Spo12 PF05032.7 EIW82052.1 - 1.4e-08 34.2 0.1 1.4e-08 34.2 0.1 2.0 2 0 0 2 2 2 1 Spo12 family Phage_tail_S PF05069.8 EIW82052.1 - 0.0043 16.8 1.3 0.0066 16.2 0.3 1.7 1 1 0 1 1 1 1 Phage virion morphogenesis family PRCC PF10253.4 EIW82052.1 - 1.1 9.8 7.7 2.1 9.0 5.3 1.5 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Chitin_synth_1 PF01644.12 EIW82053.1 - 5.2e-65 218.2 0.1 8.6e-65 217.4 0.1 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EIW82053.1 - 5.5e-25 86.8 0.5 1.3e-24 85.7 0.3 1.6 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EIW82053.1 - 1.2e-24 86.5 0.0 2e-20 72.6 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EIW82053.1 - 1.8e-06 27.9 0.0 5.7e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Polyketide_cyc PF03364.15 EIW82055.1 - 1.5e-24 86.4 0.0 1.8e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport HPP PF04982.8 EIW82057.1 - 1.2e-37 128.3 6.5 1.2e-37 128.3 4.5 1.7 2 0 0 2 2 2 1 HPP family YjgP_YjgQ PF03739.9 EIW82057.1 - 0.31 9.7 3.2 0.16 10.7 0.1 1.9 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family Tmemb_14 PF03647.8 EIW82057.1 - 1.5 9.2 8.8 0.23 11.8 1.6 2.3 1 1 1 2 2 2 0 Transmembrane proteins 14C 14-3-3 PF00244.15 EIW82058.1 - 2.3e-73 246.1 0.3 2.6e-73 245.9 0.2 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF1943 PF09172.6 EIW82058.1 - 0.12 11.2 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DS PF01916.12 EIW82059.1 - 3.1e-138 459.9 0.0 3.6e-138 459.7 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Sec7 PF01369.15 EIW82060.1 - 1.5e-64 217.2 0.1 3.9e-64 215.8 0.1 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EIW82060.1 - 2.6e-54 183.1 5.0 2.6e-54 183.1 3.5 2.7 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EIW82060.1 - 6.2e-31 105.7 7.8 1.4e-30 104.6 0.3 4.9 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) HEAT PF02985.17 EIW82060.1 - 0.0042 17.0 0.0 0.71 10.1 0.0 4.0 3 0 0 3 3 3 1 HEAT repeat Cas_APE2256 PF09651.5 EIW82060.1 - 0.047 13.4 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) SCA7 PF08313.7 EIW82061.1 - 7e-29 99.2 0.1 7e-29 99.2 0.0 2.0 2 0 0 2 2 2 1 SCA7, zinc-binding domain zf-RING_2 PF13639.1 EIW82062.1 - 1.7e-10 40.5 3.0 3.9e-10 39.3 2.0 1.6 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIW82062.1 - 1.9e-07 30.9 3.0 2e-06 27.6 0.3 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EIW82062.1 - 2.5e-07 30.7 0.3 6.9e-07 29.2 0.1 1.7 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EIW82062.1 - 1.6e-06 27.7 2.7 3.9e-06 26.4 2.0 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIW82062.1 - 1.8e-06 27.5 0.1 3.3e-06 26.6 0.1 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIW82062.1 - 7.7e-06 25.5 0.2 2.4e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EIW82062.1 - 2.4e-05 23.8 2.5 9.9e-05 21.9 1.7 1.8 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIW82062.1 - 0.0002 21.1 0.9 0.00048 19.9 0.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EIW82062.1 - 0.00053 19.5 1.1 0.0026 17.3 0.2 2.2 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EIW82062.1 - 0.013 15.3 1.6 0.013 15.3 1.1 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C2HC5 PF06221.8 EIW82062.1 - 0.025 14.3 0.7 0.051 13.3 0.1 1.7 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type zf-Nse PF11789.3 EIW82062.1 - 0.046 13.2 0.2 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_3 PF14369.1 EIW82062.1 - 0.1 12.6 2.6 3.2 7.8 0.3 2.7 2 0 0 2 2 2 0 zinc-finger FANCL_C PF11793.3 EIW82062.1 - 0.54 10.2 3.7 6.6 6.7 2.6 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.1 EIW82062.1 - 9.1 5.9 12.0 2.8 7.5 3.3 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Sec10 PF07393.6 EIW82063.1 - 2.5e-222 740.0 0.1 3.2e-222 739.6 0.1 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec10 Peptidase_S46 PF10459.4 EIW82063.1 - 0.0051 15.2 0.4 0.0083 14.5 0.3 1.2 1 0 0 1 1 1 1 Peptidase S46 DUF2363 PF10155.4 EIW82063.1 - 0.065 13.1 0.1 9.3 6.1 0.1 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2363) RIX1 PF08167.7 EIW82064.1 - 3.4e-18 65.8 3.8 5.2e-18 65.2 0.8 2.4 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Gp_UL130 PF11668.3 EIW82064.1 - 0.076 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 HCMV glycoprotein pUL130 RNA_pol_I_TF PF04090.7 EIW82065.1 - 4.4e-10 39.1 2.5 3.4e-08 33.0 0.3 2.1 1 1 1 2 2 2 2 RNA polymerase I specific initiation factor TPR_16 PF13432.1 EIW82065.1 - 0.096 13.3 0.3 2.1 9.1 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EIW82065.1 - 0.12 12.7 0.0 1 9.7 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat FEZ PF07763.8 EIW82066.1 - 0.035 13.8 0.7 0.21 11.2 0.1 2.1 2 0 0 2 2 2 0 FEZ-like protein IL13 PF03487.8 EIW82066.1 - 5 6.9 5.6 3 7.6 0.2 2.7 3 0 0 3 3 3 0 Interleukin-13 RNA_pol_Rpb1_5 PF04998.12 EIW82067.1 - 7.2e-91 304.2 0.0 1.3e-90 303.4 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EIW82067.1 - 9.5e-61 204.5 0.1 2e-60 203.5 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EIW82067.1 - 1.3e-35 122.4 0.0 2.8e-35 121.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EIW82067.1 - 8e-34 117.3 0.7 4.4e-23 82.0 0.0 3.9 4 0 0 4 4 4 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EIW82067.1 - 2.6e-20 72.1 0.0 7.6e-20 70.6 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RRM_1 PF00076.17 EIW82070.1 - 6.2e-18 64.2 0.1 6.2e-18 64.2 0.1 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW82070.1 - 2.5e-15 56.1 0.0 4.4e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW82070.1 - 3.7e-11 42.7 0.0 3.7e-11 42.7 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIW82070.1 - 0.034 13.9 0.1 0.078 12.8 0.1 1.6 1 1 0 1 1 1 0 RNA binding motif DEAD PF00270.24 EIW82071.1 - 5.4e-41 139.8 0.1 1e-40 139.0 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW82071.1 - 3.3e-27 94.1 0.2 7e-27 93.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW82071.1 - 0.0071 16.2 0.0 0.058 13.2 0.0 2.1 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EIW82071.1 - 0.0072 16.0 0.1 0.019 14.6 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EIW82071.1 - 0.0084 16.2 0.2 0.032 14.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain Syja_N PF02383.13 EIW82072.1 - 5.5e-79 265.2 0.0 7.5e-79 264.7 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EIW82072.1 - 2.8e-24 86.3 0.7 5.9e-24 85.3 0.5 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SseB_C PF14581.1 EIW82072.1 - 0.14 12.0 0.0 14 5.6 0.0 2.6 2 0 0 2 2 2 0 SseB protein C-terminal domain Erv26 PF04148.8 EIW82074.1 - 3.3e-55 186.7 3.6 3.8e-55 186.5 2.5 1.0 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Snf7 PF03357.16 EIW82075.1 - 7.4e-18 64.5 15.0 1e-17 64.0 10.4 1.2 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 EIW82075.1 - 0.0012 18.2 4.4 0.002 17.5 3.0 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway DDE_Tnp_Tn3 PF01526.12 EIW82075.1 - 0.012 14.2 1.7 0.019 13.5 1.2 1.3 1 0 0 1 1 1 0 Tn3 transposase DDE domain IMP_cyclohyd PF07826.6 EIW82075.1 - 0.013 14.8 0.2 0.015 14.6 0.2 1.2 1 0 0 1 1 1 0 IMP cyclohydrolase-like protein DUF1049 PF06305.6 EIW82075.1 - 0.26 10.7 1.0 0.77 9.2 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) SYCE1 PF15233.1 EIW82075.1 - 0.35 10.7 7.3 3.4 7.6 5.1 2.1 1 1 0 1 1 1 0 Synaptonemal complex central element protein 1 T2SM PF04612.7 EIW82075.1 - 2.7 7.7 8.1 0.25 11.1 0.2 2.3 2 1 0 2 2 2 0 Type II secretion system (T2SS), protein M GrpE PF01025.14 EIW82075.1 - 2.7 7.4 7.6 2.5 7.5 4.3 1.7 1 1 1 2 2 2 0 GrpE Prominin PF05478.6 EIW82075.1 - 6.7 4.1 10.4 35 1.7 6.5 1.8 1 1 0 1 1 1 0 Prominin Abhydrolase_1 PF00561.15 EIW82077.1 - 4.6e-17 62.3 0.2 7.6e-15 55.0 0.2 2.4 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIW82077.1 - 4.9e-11 42.9 1.6 2.6e-10 40.5 1.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EIW82077.1 - 0.00012 21.6 0.1 0.00021 20.8 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Aldedh PF00171.17 EIW82078.1 - 1.5e-146 488.4 0.0 1.8e-146 488.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIW82078.1 - 2.3e-05 23.3 0.0 6.9e-05 21.7 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) RCC1 PF00415.13 EIW82079.1 - 6.9e-51 170.2 5.7 6.2e-09 35.9 0.0 7.1 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EIW82079.1 - 6.6e-36 121.1 29.1 8.2e-07 28.4 1.4 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat Spermine_synth PF01564.12 EIW82080.1 - 5.9e-06 25.4 0.0 7.5e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_26 PF13659.1 EIW82080.1 - 0.0022 18.0 0.1 0.005 16.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain TORC_M PF12885.2 EIW82080.1 - 0.098 12.4 0.0 0.26 11.0 0.0 1.8 1 0 0 1 1 1 0 Transducer of regulated CREB activity middle domain Peptidase_M28 PF04389.12 EIW82081.1 - 2.8e-15 56.5 0.0 1.2e-14 54.4 0.0 2.0 1 1 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 EIW82081.1 - 6.2e-14 51.6 0.0 1.4e-13 50.5 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 EIW82081.1 - 7.5e-09 35.2 0.1 1.8e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 PA domain Nicastrin PF05450.10 EIW82081.1 - 0.056 12.6 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Nicastrin Alpha-amylase_C PF02806.13 EIW82082.1 - 1.1e-20 73.5 0.0 3.1e-20 72.0 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EIW82082.1 - 3e-17 63.0 0.2 1.5e-14 54.1 0.0 2.9 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EIW82082.1 - 2.4e-14 53.1 0.1 5.9e-14 51.8 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) RuBisCO_large PF00016.15 EIW82082.1 - 0.027 13.3 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, catalytic domain VP4_haemagglut PF00426.13 EIW82082.1 - 0.036 12.0 0.2 0.053 11.4 0.1 1.1 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) DUF2370 PF10176.4 EIW82083.1 - 4.1e-60 203.0 0.6 5e-60 202.7 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2370) B3_4 PF03483.12 EIW82084.1 - 1.2e-25 90.0 0.0 2e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EIW82084.1 - 9.6e-17 60.5 0.0 1.6e-13 50.2 0.0 2.7 2 0 0 2 2 2 2 tRNA synthetase B5 domain MFS_2 PF13347.1 EIW82085.1 - 1.5e-10 40.0 5.4 1.5e-10 40.0 3.8 2.3 1 1 0 2 2 2 1 MFS/sugar transport protein DUF3918 PF13056.1 EIW82085.1 - 0.12 11.6 0.0 0.31 10.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) Shisa PF13908.1 EIW82085.1 - 0.14 12.3 0.9 0.44 10.7 0.2 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Ank_4 PF13637.1 EIW82086.1 - 6.6e-25 87.0 1.2 4.5e-12 46.1 0.0 4.7 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIW82086.1 - 1.1e-21 76.9 0.0 6.9e-15 55.1 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIW82086.1 - 3.9e-21 74.5 0.4 4.7e-11 42.5 0.0 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EIW82086.1 - 4.3e-20 70.4 0.0 2.7e-08 33.2 0.0 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.1 EIW82086.1 - 2.7e-15 54.9 0.0 6.4e-06 25.9 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat CALCOCO1 PF07888.6 EIW82089.1 - 0.041 12.1 0.4 0.074 11.3 0.3 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like HAP1_N PF04849.8 EIW82089.1 - 0.043 12.7 2.5 0.088 11.7 1.8 1.5 1 1 0 1 1 1 0 HAP1 N-terminal conserved region BicD PF09730.4 EIW82089.1 - 0.069 11.4 4.2 0.12 10.7 2.9 1.4 1 1 0 1 1 1 0 Microtubule-associated protein Bicaudal-D TMF_DNA_bd PF12329.3 EIW82089.1 - 0.32 10.8 5.8 0.68 9.7 0.2 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EIW82089.1 - 0.91 9.0 8.4 7 6.1 5.8 2.0 1 1 0 1 1 1 0 IncA protein DUF1793 PF08760.6 EIW82090.1 - 4.2e-59 199.2 1.9 4.2e-59 199.2 1.3 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF1793) FAD_binding_7 PF03441.9 EIW82091.1 - 1.3e-92 309.9 0.2 3.7e-92 308.4 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EIW82091.1 - 2e-35 122.0 0.0 3.2e-35 121.3 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase Thioredoxin PF00085.15 EIW82092.1 - 0.001 18.6 0.1 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 EIW82092.1 - 0.019 13.7 0.0 0.022 13.4 0.0 1.2 1 0 0 1 1 1 0 Phosducin eRF1_1 PF03463.10 EIW82093.1 - 2.8e-42 143.4 0.0 4.7e-42 142.6 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.10 EIW82093.1 - 8.4e-22 77.5 0.0 1.5e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.10 EIW82093.1 - 1.2e-17 64.4 0.0 2e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 OMPdecase PF00215.19 EIW82094.1 - 1.8e-74 249.9 0.0 2.2e-74 249.6 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family TruD PF01142.13 EIW82095.1 - 1.2e-63 215.1 0.0 2.5e-62 210.7 0.0 2.5 1 1 0 1 1 1 1 tRNA pseudouridine synthase D (TruD) tRNA-synt_1d PF00750.14 EIW82095.1 - 0.074 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (R) MFS_1 PF07690.11 EIW82096.1 - 2.4e-30 105.4 14.4 2.4e-30 105.4 10.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Gly_transf_sug PF04488.10 EIW82097.1 - 3.2e-20 72.4 0.1 6.8e-20 71.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EIW82097.1 - 0.0014 17.1 0.6 0.1 11.0 0.0 2.1 2 0 0 2 2 2 2 TcdA/TcdB catalytic glycosyltransferase domain DUF3017 PF11222.3 EIW82097.1 - 0.04 13.6 0.3 0.11 12.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3017) HTH_8 PF02954.14 EIW82097.1 - 0.12 11.8 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory protein, Fis family PIN_4 PF13638.1 EIW82098.1 - 2.1e-21 76.4 0.0 3.4e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 PIN domain PIN PF01850.16 EIW82098.1 - 0.082 13.2 0.1 0.24 11.7 0.0 1.8 1 1 0 1 1 1 0 PIN domain CTD_bind PF04818.8 EIW82099.1 - 0.00047 20.3 0.0 0.0017 18.5 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CFIA_Pcf11 PF11526.3 EIW82099.1 - 0.016 15.3 0.8 1.2 9.2 0.0 3.0 3 0 0 3 3 3 0 Subunit of cleavage factor IA Pcf11 Ribosomal_L6 PF00347.18 EIW82100.1 - 2.4e-30 104.8 4.0 4.8e-16 59.0 1.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 GTP_EFTU PF00009.22 EIW82101.1 - 1.6e-47 161.3 0.0 2.5e-47 160.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EIW82101.1 - 3.8e-16 58.7 0.0 6.3e-09 35.5 0.0 2.4 2 0 0 2 2 2 2 Elongation factor G C-terminus EFG_II PF14492.1 EIW82101.1 - 2.4e-15 56.1 0.0 4.6e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EIW82101.1 - 2.1e-06 27.7 0.0 4.4e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIW82101.1 - 0.00035 20.4 0.0 0.00068 19.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIW82101.1 - 0.07 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein ADH_N PF08240.7 EIW82103.1 - 1.1e-29 102.4 0.1 1.8e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW82103.1 - 6.9e-23 80.6 0.1 1.1e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW82103.1 - 2.3e-05 25.2 0.0 4.9e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EIW82103.1 - 0.0095 15.3 0.2 0.019 14.3 0.2 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_18 PF12847.2 EIW82103.1 - 0.04 14.5 0.0 0.067 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 2-Hacid_dh_C PF02826.14 EIW82103.1 - 0.073 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 EIW82103.1 - 0.074 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EIW82103.1 - 0.075 12.1 0.6 0.11 11.5 0.4 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Pkinase PF00069.20 EIW82104.1 - 6.6e-52 176.2 0.0 8.5e-52 175.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW82104.1 - 2e-27 95.8 0.0 2.6e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW82104.1 - 0.003 17.3 0.1 0.012 15.3 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIW82104.1 - 0.018 14.6 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 EIW82104.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EIW82104.1 - 0.15 11.1 0.1 0.23 10.5 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Meth_synt_2 PF01717.13 EIW82105.1 - 2.1e-143 477.1 0.0 3.2e-139 463.4 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EIW82105.1 - 3.5e-122 407.5 0.0 9.7e-110 366.6 0.0 3.1 3 0 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain DUF2985 PF11204.3 EIW82106.1 - 2.8e-25 87.8 4.8 5.1e-25 87.0 3.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) Apt1 PF10351.4 EIW82107.1 - 9.6e-80 268.6 0.2 1.6e-79 267.9 0.1 1.3 1 0 0 1 1 1 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EIW82107.1 - 5.8e-57 193.1 0.0 1.1e-54 185.6 0.0 2.3 1 1 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_GFWDK PF10347.4 EIW82107.1 - 2.5e-40 137.9 1.3 7.3e-40 136.4 0.1 2.4 3 0 0 3 3 3 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EIW82107.1 - 1.2e-20 73.7 0.0 5.6e-20 71.6 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_SW PF10305.4 EIW82107.1 - 9.6e-09 35.6 0.0 1.1e-07 32.1 0.0 2.6 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain Ribosomal_L6e PF01159.14 EIW82108.1 - 1.9e-38 130.9 0.2 2.7e-38 130.5 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.10 EIW82108.1 - 1.4e-07 31.2 1.5 2e-07 30.8 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L6, N-terminal domain UPF0183 PF03676.9 EIW82109.1 - 1.7e-40 138.8 0.0 2.8e-31 108.4 0.0 2.0 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0183) DNA_pol_E_B PF04042.11 EIW82110.1 - 1.1e-41 142.4 0.3 1.9e-41 141.6 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B 60KD_IMP PF02096.15 EIW82111.1 - 4.7e-20 72.1 0.1 1.6e-19 70.4 0.0 1.8 1 1 0 1 1 1 1 60Kd inner membrane protein APP_E2 PF12925.2 EIW82111.1 - 0.024 14.2 0.2 0.024 14.2 0.1 1.8 2 0 0 2 2 2 0 E2 domain of amyloid precursor protein RNase_T PF00929.19 EIW82112.1 - 2.3e-17 63.7 0.0 7.6e-17 62.0 0.0 1.8 2 0 0 2 2 2 1 Exonuclease CHORD PF04968.7 EIW82112.1 - 0.023 14.9 2.4 0.055 13.7 1.7 1.6 1 0 0 1 1 1 0 CHORD TRAM_LAG1_CLN8 PF03798.11 EIW82113.1 - 2e-30 105.8 22.2 2e-30 105.8 15.4 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EIW82113.1 - 1.1e-14 53.6 0.1 2.8e-14 52.3 0.1 1.8 1 0 0 1 1 1 1 TRAM1-like protein Histone PF00125.19 EIW82115.1 - 1.2e-28 99.0 0.3 2.2e-28 98.1 0.2 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIW82115.1 - 0.00083 19.4 0.2 0.0014 18.7 0.2 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EIW82115.1 - 0.01 15.8 0.2 0.022 14.8 0.1 1.6 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EIW82115.1 - 0.83 8.8 9.7 6 6.0 6.7 1.9 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T MIP-T3 PF10243.4 EIW82116.1 - 0.003 16.1 16.8 0.0047 15.4 11.7 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF572 PF04502.8 EIW82116.1 - 0.52 9.4 18.8 1.3 8.2 13.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF1104 PF06518.6 EIW82117.1 - 0.076 13.1 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1104) TF_Zn_Ribbon PF08271.7 EIW82117.1 - 0.079 12.2 1.7 0.12 11.6 0.0 2.3 2 0 0 2 2 2 0 TFIIB zinc-binding DnaJ PF00226.26 EIW82118.1 - 7.2e-18 64.0 0.0 1.4e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain DAP PF15228.1 EIW82118.1 - 4.3 8.1 7.8 15 6.3 3.5 2.3 2 0 0 2 2 2 0 Death-associated protein Gln-synt_C PF00120.19 EIW82119.1 - 1.7e-61 207.6 0.0 2e-61 207.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EIW82119.1 - 6.5e-18 64.1 0.0 1.3e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain Iso_dh PF00180.15 EIW82121.1 - 3.4e-79 266.3 0.1 4.3e-79 265.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Abhydrolase_6 PF12697.2 EIW82122.1 - 7.9e-08 32.4 0.0 2.1e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW82122.1 - 0.00032 20.4 0.0 0.00087 19.0 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EIW82122.1 - 0.13 11.7 0.0 0.32 10.3 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Piwi PF02171.12 EIW82123.1 - 2.9e-87 292.4 0.0 4.2e-87 291.9 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EIW82123.1 - 2.1e-17 62.2 0.0 5e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EIW82123.1 - 5.5e-07 28.9 0.0 1.1e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 PAZ domain TspO_MBR PF03073.10 EIW82124.1 - 7.2e-39 132.6 5.4 8.4e-39 132.4 3.7 1.0 1 0 0 1 1 1 1 TspO/MBR family SBF PF01758.11 EIW82124.1 - 0.14 11.5 2.5 5.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Sodium Bile acid symporter family DivIC PF04977.10 EIW82125.1 - 0.0066 15.9 0.0 0.0092 15.4 0.0 1.2 1 0 0 1 1 1 1 Septum formation initiator Spc24 PF08286.6 EIW82125.1 - 0.027 14.1 0.2 0.037 13.7 0.2 1.1 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 ALIX_LYPXL_bnd PF13949.1 EIW82125.1 - 0.06 12.3 0.4 0.068 12.1 0.3 1.0 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV AKNA PF12443.3 EIW82125.1 - 0.099 12.6 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 AT-hook-containing transcription factor Snf7 PF03357.16 EIW82126.1 - 6.7e-30 103.7 17.7 6.7e-30 103.7 12.3 1.5 1 1 0 1 1 1 1 Snf7 DUF2428 PF10350.4 EIW82126.1 - 0.014 14.3 0.2 0.02 13.9 0.2 1.3 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) Iso_dh PF00180.15 EIW82127.1 - 3.5e-100 335.3 0.0 4.3e-100 335.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RNB PF00773.14 EIW82128.1 - 7.7e-95 317.8 0.2 1.5e-94 316.9 0.1 1.5 1 0 0 1 1 1 1 RNB domain RTA1 PF04479.8 EIW82130.1 - 1.6e-42 145.5 3.1 1.6e-42 145.5 2.1 1.6 1 1 0 1 1 1 1 RTA1 like protein VID27 PF08553.5 EIW82131.1 - 7.6e-236 785.1 1.1 1.7e-198 661.6 0.8 2.0 1 1 1 2 2 2 2 VID27 cytoplasmic protein Nuf2 PF03800.9 EIW82131.1 - 0.095 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Nuf2 family Daxx PF03344.10 EIW82131.1 - 0.21 10.0 4.0 0.3 9.5 2.7 1.2 1 0 0 1 1 1 0 Daxx Family Nop14 PF04147.7 EIW82131.1 - 8.4 4.1 10.7 13 3.5 7.4 1.2 1 0 0 1 1 1 0 Nop14-like family CRCB PF02537.10 EIW82132.1 - 2.3e-31 108.1 19.0 2.1e-19 69.5 4.6 2.5 2 1 0 2 2 2 2 CrcB-like protein CK_II_beta PF01214.13 EIW82133.1 - 3e-78 261.5 0.0 4.3e-78 261.0 0.0 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DUF1032 PF06278.6 EIW82133.1 - 0.52 8.7 5.2 0.98 7.8 3.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1032) YL1 PF05764.8 EIW82133.1 - 7.3 6.1 12.7 13 5.2 8.8 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Ribosomal_L36e PF01158.13 EIW82134.1 - 1.1e-39 134.3 2.7 1.2e-39 134.2 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e INT_SG_DDX_CT_C PF15300.1 EIW82134.1 - 0.033 13.6 0.8 0.11 11.9 0.0 2.1 2 1 1 3 3 3 0 INTS6/SAGE1/DDX26B/CT45 C-terminus 4HB_MCP_1 PF12729.2 EIW82134.1 - 0.071 12.4 0.1 0.089 12.1 0.0 1.1 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction SNARE_assoc PF09335.6 EIW82135.1 - 4.4e-17 62.4 4.5 4.4e-17 62.4 3.1 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein Mito_carr PF00153.22 EIW82136.1 - 2.5e-64 213.0 3.0 1.3e-21 76.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EIW82136.1 - 8.8e-06 25.7 0.0 2.9e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EIW82136.1 - 0.00032 19.8 0.6 0.093 12.0 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EIW82136.1 - 0.0015 18.2 0.0 0.14 12.1 0.0 2.9 2 0 0 2 2 2 1 EF-hand domain Amidohydro_2 PF04909.9 EIW82137.1 - 4.1e-27 95.4 1.9 4.9e-27 95.1 1.3 1.1 1 0 0 1 1 1 1 Amidohydrolase adh_short PF00106.20 EIW82138.1 - 2.7e-31 108.7 1.0 3.8e-31 108.2 0.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW82138.1 - 1.7e-16 60.7 0.0 2.4e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW82138.1 - 5.6e-16 58.7 0.6 9.1e-16 58.0 0.4 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIW82138.1 - 5.8e-06 26.4 0.1 1.1e-05 25.5 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EIW82138.1 - 0.00037 19.8 0.3 0.04 13.1 0.2 2.1 2 0 0 2 2 2 1 NmrA-like family Eno-Rase_NADH_b PF12242.3 EIW82138.1 - 0.00051 19.7 0.1 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EIW82138.1 - 0.00065 19.2 0.1 0.0013 18.2 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIW82138.1 - 0.0045 15.7 0.1 0.0065 15.2 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EIW82138.1 - 0.0061 15.4 0.1 0.0087 14.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RNase_P_p30 PF01876.11 EIW82138.1 - 0.049 12.8 0.0 0.11 11.7 0.0 1.5 1 1 0 1 1 1 0 RNase P subunit p30 Sec23_trunk PF04811.10 EIW82138.1 - 0.077 12.3 0.1 0.58 9.4 0.0 2.0 1 1 1 2 2 2 0 Sec23/Sec24 trunk domain Saccharop_dh PF03435.13 EIW82138.1 - 0.082 11.8 0.2 0.11 11.3 0.2 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Histidinol_dh PF00815.15 EIW82139.1 - 1.9e-174 580.1 0.3 3.4e-174 579.3 0.1 1.4 2 0 0 2 2 2 1 Histidinol dehydrogenase PRA-CH PF01502.13 EIW82139.1 - 2e-25 88.2 0.1 4.7e-25 87.0 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EIW82139.1 - 2.4e-11 43.7 0.1 1.8e-10 40.9 0.1 2.4 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase ABC_tran PF00005.22 EIW82140.1 - 4.2e-17 62.7 0.0 1.1e-16 61.3 0.0 1.7 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIW82140.1 - 1.9e-12 47.7 0.1 2.7e-06 27.5 0.0 2.1 1 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EIW82140.1 - 4.3e-05 22.9 0.0 5.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EIW82140.1 - 0.00011 21.3 0.0 0.025 13.6 0.0 2.0 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EIW82140.1 - 0.00035 20.0 0.1 0.00073 19.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EIW82140.1 - 0.0016 17.6 0.0 0.0023 17.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EIW82140.1 - 0.012 15.1 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 EIW82140.1 - 0.016 15.5 0.1 0.024 14.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.14 EIW82140.1 - 0.022 13.9 0.3 0.52 9.4 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 EIW82140.1 - 0.026 13.9 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain SRP54 PF00448.17 EIW82140.1 - 0.028 13.8 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_17 PF13207.1 EIW82140.1 - 0.052 14.3 0.4 0.12 13.2 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EIW82140.1 - 0.055 13.4 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EIW82140.1 - 0.065 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.7 EIW82140.1 - 0.083 12.5 0.1 0.18 11.4 0.1 1.5 2 0 0 2 2 1 0 NACHT domain AAA_33 PF13671.1 EIW82140.1 - 0.12 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EIW82140.1 - 0.14 11.8 1.1 2.2 7.9 0.1 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.18 EIW82140.1 - 0.15 11.9 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 EIW82140.1 - 0.18 11.9 0.3 0.57 10.3 0.2 1.9 1 1 0 1 1 1 0 AAA domain MutS_V PF00488.16 EIW82140.1 - 0.21 10.9 0.2 0.43 9.9 0.0 1.5 2 0 0 2 2 2 0 MutS domain V Opy2 PF09463.5 EIW82141.1 - 1e-06 28.7 21.7 1.8e-06 27.9 15.0 1.4 1 0 0 1 1 1 1 Opy2 protein IncA PF04156.9 EIW82141.1 - 0.065 12.8 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 IncA protein UQ_con PF00179.21 EIW82142.1 - 2.2e-21 75.7 0.0 3.8e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IBR PF01485.16 EIW82142.1 - 0.00025 20.8 2.1 0.00053 19.7 1.5 1.5 1 0 0 1 1 1 1 IBR domain Mito_carr PF00153.22 EIW82143.1 - 4.2e-53 177.0 4.8 2.6e-17 62.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PrcB_C PF14343.1 EIW82143.1 - 0.046 13.4 0.1 11 5.8 0.0 2.6 2 0 0 2 2 2 0 PrcB C-terminal Glyco_hydro_31 PF01055.21 EIW82144.1 - 2.6e-166 553.8 5.5 3.4e-166 553.4 3.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EIW82144.1 - 9.7e-12 44.5 0.7 9.7e-12 44.5 0.5 2.8 4 0 0 4 4 4 1 Galactose mutarotase-like Peptidase_M24 PF00557.19 EIW82145.1 - 1.7e-55 187.8 0.0 2.3e-55 187.3 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EIW82145.1 - 8.8e-35 119.0 0.0 1.6e-34 118.1 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Lipase_3 PF01764.20 EIW82146.1 - 2.8e-17 62.6 0.0 5.5e-17 61.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EIW82146.1 - 0.085 12.6 0.2 0.26 11.0 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Spt4 PF06093.8 EIW82147.1 - 3.2e-30 103.8 0.1 3.9e-30 103.5 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Med13_C PF06333.7 EIW82148.1 - 2.9e-17 62.3 0.0 2.9e-17 62.3 0.0 2.7 2 1 0 2 2 2 1 Mediator complex subunit 13 C-terminal FAD_binding_3 PF01494.14 EIW82149.1 - 7e-46 156.8 0.0 9.5e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain SNF2_N PF00176.18 EIW82150.1 - 2.7e-67 226.7 0.0 4.1e-67 226.0 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW82150.1 - 2.4e-11 43.3 0.0 5.3e-11 42.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW82150.1 - 2.3e-08 34.1 0.0 5.9e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EIW82150.1 - 1.2e-07 31.4 0.0 9.5e-07 28.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.20 EIW82150.1 - 1.2e-05 24.8 3.5 1.2e-05 24.8 2.4 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW82150.1 - 1.6e-05 24.6 4.3 1.6e-05 24.6 3.0 2.5 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIW82150.1 - 9.5e-05 22.3 3.4 9.5e-05 22.3 2.3 2.7 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EIW82150.1 - 0.00066 19.1 2.6 0.0017 17.8 1.8 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_3 PF13920.1 EIW82150.1 - 0.0024 17.4 3.7 0.0024 17.4 2.5 2.7 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIW82150.1 - 0.003 17.3 3.2 0.003 17.3 2.2 2.3 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EIW82150.1 - 0.0033 17.4 0.5 0.0033 17.4 0.4 2.1 2 0 0 2 2 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EIW82150.1 - 0.0067 16.1 0.8 0.018 14.8 0.5 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EIW82150.1 - 0.014 15.2 0.4 0.047 13.5 0.3 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DEAD_2 PF06733.10 EIW82150.1 - 0.032 13.6 0.1 0.15 11.4 0.1 2.2 1 1 0 1 1 1 0 DEAD_2 U79_P34 PF03064.11 EIW82150.1 - 2.9 7.3 10.5 4.7 6.6 7.3 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 WW PF00397.21 EIW82152.1 - 0.018 14.8 6.8 0.023 14.5 0.8 2.4 2 0 0 2 2 2 0 WW domain HMG_box PF00505.14 EIW82153.1 - 2.1e-16 59.9 3.3 5e-16 58.7 2.3 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIW82153.1 - 3.5e-13 49.7 3.7 8.9e-13 48.4 2.6 1.8 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 EIW82153.1 - 0.0084 15.4 0.4 0.026 13.8 0.3 1.8 1 1 0 1 1 1 1 Mating-type protein MAT alpha 1 CDC45 PF02724.9 EIW82153.1 - 0.89 7.5 14.5 3 5.7 6.6 2.2 2 0 0 2 2 2 0 CDC45-like protein Med26 PF08711.6 EIW82154.1 - 2.9e-07 29.8 0.1 5.8e-07 28.9 0.1 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-CCCH PF00642.19 EIW82154.1 - 4.2e-07 29.5 3.8 7.6e-07 28.6 2.7 1.3 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EIW82154.1 - 0.33 11.0 2.3 0.67 10.0 1.6 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type Ribosomal_S4 PF00163.14 EIW82155.1 - 1.6e-13 50.7 0.6 2.3e-13 50.3 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EIW82155.1 - 6.2e-11 41.5 0.0 1.1e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 S4 domain Kinesin PF00225.18 EIW82156.1 - 7.9e-110 366.6 0.0 1.3e-109 366.0 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain DUF3694 PF12473.3 EIW82156.1 - 7.5e-40 135.8 0.0 2.7e-39 134.0 0.0 2.1 2 0 0 2 2 2 1 Kinesin protein PH PF00169.24 EIW82156.1 - 1.1e-11 44.8 0.0 5.5e-11 42.5 0.0 2.2 2 0 0 2 2 2 1 PH domain FHA PF00498.21 EIW82156.1 - 5.6e-08 32.7 0.0 2.8e-07 30.5 0.0 2.2 2 0 0 2 2 2 1 FHA domain KIF1B PF12423.3 EIW82156.1 - 0.00018 21.4 0.1 0.00055 19.9 0.1 1.9 1 0 0 1 1 1 1 Kinesin protein 1B PH_11 PF15413.1 EIW82156.1 - 0.046 13.9 0.0 0.16 12.2 0.0 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain gag_pre-integrs PF13976.1 EIW82156.1 - 0.11 12.1 0.0 0.32 10.6 0.0 1.7 1 0 0 1 1 1 0 GAG-pre-integrase domain CMAS PF02353.15 EIW82157.1 - 1.4e-57 194.8 0.0 2e-57 194.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EIW82157.1 - 4.4e-08 32.9 0.0 7.7e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW82157.1 - 1.8e-06 28.5 0.0 3.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW82157.1 - 2.5e-06 27.8 0.0 6.1e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW82157.1 - 0.00069 19.2 0.0 0.0013 18.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW82157.1 - 0.005 16.2 0.0 0.0098 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EIW82157.1 - 0.012 16.0 0.0 0.029 14.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SAC3 PF12209.3 EIW82157.1 - 0.016 15.3 0.0 0.037 14.1 0.0 1.6 1 0 0 1 1 1 0 Leucine permease transcriptional regulator helical domain Methyltransf_26 PF13659.1 EIW82157.1 - 0.024 14.6 0.0 0.05 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Arf PF00025.16 EIW82158.1 - 2.6e-69 231.9 0.2 3e-69 231.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EIW82158.1 - 1.4e-13 50.3 2.9 2.2e-08 33.1 0.2 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EIW82158.1 - 3e-11 42.8 0.0 4.1e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EIW82158.1 - 5.9e-11 41.9 0.0 7.2e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EIW82158.1 - 1.2e-08 34.8 0.0 1.7e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.17 EIW82158.1 - 1.5e-07 30.9 0.0 2e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW82158.1 - 2.7e-07 31.0 0.0 3.9e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EIW82158.1 - 2.5e-05 23.8 0.0 0.0012 18.3 0.0 2.1 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EIW82158.1 - 0.015 14.8 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Dynamin_N PF00350.18 EIW82158.1 - 0.029 14.1 0.0 0.45 10.3 0.0 2.1 2 0 0 2 2 2 0 Dynamin family FeoB_N PF02421.13 EIW82158.1 - 0.056 12.7 0.1 0.16 11.2 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B GTP_EFTU PF00009.22 EIW82159.1 - 3e-32 111.5 0.0 2e-31 108.9 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EIW82159.1 - 9.5e-17 60.8 0.3 2.6e-16 59.4 0.0 1.9 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EIW82159.1 - 1.4e-11 44.3 11.4 6.4e-09 35.8 0.0 3.7 4 0 0 4 4 4 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIW82159.1 - 5.8e-07 29.4 0.1 1.9e-06 27.8 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EIW82159.1 - 0.0033 17.5 0.0 0.0095 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain Ras PF00071.17 EIW82159.1 - 0.0073 15.7 0.0 0.056 12.8 0.0 2.5 1 1 0 1 1 1 1 Ras family ATP_bind_1 PF03029.12 EIW82159.1 - 0.018 14.5 0.0 0.042 13.3 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AA_permease_2 PF13520.1 EIW82160.1 - 5.3e-40 137.2 45.1 6.5e-40 136.9 31.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIW82160.1 - 7.4e-17 60.8 39.9 9e-17 60.5 27.7 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1774 PF08611.5 EIW82160.1 - 0.38 10.9 14.4 0.12 12.5 0.4 3.5 3 0 0 3 3 3 0 Fungal protein of unknown function (DUF1774) His_Phos_2 PF00328.17 EIW82161.1 - 2.3e-07 30.4 0.8 9.9e-05 21.8 0.5 3.0 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) FGGY_C PF02782.11 EIW82162.1 - 2.1e-45 154.7 0.0 3.5e-45 154.0 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EIW82162.1 - 1.2e-21 77.1 0.2 8.8e-21 74.3 0.2 2.3 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain BcrAD_BadFG PF01869.15 EIW82162.1 - 8.7e-06 25.2 0.3 0.0011 18.3 0.1 2.8 3 0 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family CmcH_NodU PF02543.10 EIW82162.1 - 0.0046 16.1 0.0 0.0073 15.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyltransferase FYRC PF05965.9 EIW82162.1 - 0.032 14.0 0.4 0.085 12.6 0.1 1.8 2 0 0 2 2 2 0 F/Y rich C-terminus Ribosomal_L2_C PF03947.13 EIW82163.1 - 4.1e-40 136.5 1.8 6.4e-40 135.9 1.3 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EIW82163.1 - 2e-13 50.0 0.1 3.8e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain SH3_1 PF00018.23 EIW82165.1 - 4.7e-16 57.8 0.7 7e-16 57.3 0.5 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIW82165.1 - 1.9e-13 49.7 0.2 3.3e-13 48.9 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIW82165.1 - 1.9e-09 36.8 0.0 2.7e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain ATP-synt_C PF00137.16 EIW82165.1 - 0.12 12.3 3.2 0.22 11.4 2.2 1.5 1 0 0 1 1 1 0 ATP synthase subunit C DUF605 PF04652.11 EIW82165.1 - 5.1 6.3 18.9 7 5.9 13.1 1.2 1 0 0 1 1 1 0 Vta1 like BIR PF00653.16 EIW82166.1 - 8.6e-34 115.7 2.9 1.5e-17 63.7 1.1 2.2 2 0 0 2 2 2 2 Inhibitor of Apoptosis domain zf-C3HC PF07967.8 EIW82166.1 - 8.9e-06 25.5 3.5 0.064 13.0 0.0 3.4 2 1 0 2 2 2 2 C3HC zinc finger-like zf-BED PF02892.10 EIW82166.1 - 0.012 15.3 0.0 1.4 8.7 0.0 2.6 2 0 0 2 2 2 0 BED zinc finger zf-RING_3 PF14369.1 EIW82166.1 - 0.34 10.9 2.3 5 7.2 0.0 2.6 2 1 0 2 2 2 0 zinc-finger p450 PF00067.17 EIW82167.1 - 9.1e-72 242.0 0.0 2.5e-71 240.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Cyclin PF08613.6 EIW82168.1 - 8.8e-14 52.1 0.0 1.6e-13 51.3 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EIW82168.1 - 1.2e-13 50.7 0.0 1.8e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain MIF4G_like PF09088.6 EIW82169.1 - 1e-64 217.4 0.0 1.7e-64 216.7 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 EIW82169.1 - 1.5e-39 135.8 0.0 4e-39 134.3 0.0 1.7 2 0 0 2 2 2 1 MIF4G like YscO PF07321.7 EIW82169.1 - 0.094 12.5 0.1 0.18 11.6 0.1 1.4 1 0 0 1 1 1 0 Type III secretion protein YscO MIF4G PF02854.14 EIW82169.1 - 0.19 11.1 0.0 1 8.7 0.0 2.1 2 0 0 2 2 2 0 MIF4G domain PPR_2 PF13041.1 EIW82170.1 - 3.6e-10 39.6 0.0 1.3e-05 25.0 0.0 4.2 4 0 0 4 4 4 2 PPR repeat family PPR_3 PF13812.1 EIW82170.1 - 8.4e-07 28.7 6.4 0.037 14.3 0.0 6.2 7 0 0 7 7 7 2 Pentatricopeptide repeat domain PPR PF01535.15 EIW82170.1 - 0.032 14.1 1.4 15 5.8 0.0 4.6 5 0 0 5 5 5 0 PPR repeat PPR_1 PF12854.2 EIW82170.1 - 0.069 12.6 0.8 1.2 8.6 0.0 3.3 4 0 0 4 4 4 0 PPR repeat Mito_carr PF00153.22 EIW82171.1 - 4e-58 193.1 1.4 2.5e-21 75.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Cyclin PF08613.6 EIW82172.1 - 3e-38 131.5 5.8 1.2e-37 129.5 4.0 2.1 1 1 0 1 1 1 1 Cyclin ESX-1_EspG PF14011.1 EIW82172.1 - 0.11 11.7 8.4 0.013 14.7 2.4 1.9 2 0 0 2 2 2 0 EspG family DUF2454 PF10521.4 EIW82173.1 - 9.7e-33 113.3 0.0 1.3e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) DUF485 PF04341.7 EIW82174.1 - 0.55 9.9 4.5 0.95 9.2 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF485 DUF420 PF04238.7 EIW82174.1 - 0.63 9.9 3.5 1.4 8.9 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF420) PRKCSH-like PF12999.2 EIW82175.1 - 1.8e-49 167.7 0.3 4.2e-49 166.4 0.2 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EIW82175.1 - 1.7e-25 89.2 0.0 3.4e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EIW82175.1 - 2.4e-09 37.8 0.8 6.9e-09 36.3 0.5 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein ScpA_ScpB PF02616.9 EIW82175.1 - 1.3 8.5 5.8 2.3 7.7 4.1 1.3 1 0 0 1 1 1 0 ScpA/B protein IncA PF04156.9 EIW82175.1 - 5.3 6.5 10.4 1.4 8.4 0.4 2.7 2 1 1 3 3 3 0 IncA protein Ldl_recept_a PF00057.13 EIW82175.1 - 9.7 6.1 17.4 3.2 7.7 3.4 2.8 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A Ribosomal_S25 PF03297.10 EIW82176.1 - 1.2e-40 137.7 1.6 1.4e-40 137.5 1.1 1.0 1 0 0 1 1 1 1 S25 ribosomal protein HTH_24 PF13412.1 EIW82176.1 - 0.016 14.6 1.2 0.024 14.0 0.8 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF505 PF04458.7 EIW82176.1 - 0.048 11.7 0.0 0.056 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF505) MTS PF05175.9 EIW82176.1 - 0.1 11.9 0.0 0.12 11.7 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase small domain Pro_isomerase PF00160.16 EIW82177.1 - 4.7e-45 153.5 0.2 5.3e-45 153.3 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EIW82178.1 - 1.3e-18 66.1 12.0 1.1e-07 31.4 1.0 7.0 7 1 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EIW82178.1 - 0.0039 16.9 0.1 0.2 11.3 0.0 2.8 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A DCR PF14047.1 EIW82178.1 - 0.014 15.6 0.0 0.031 14.5 0.0 1.6 1 0 0 1 1 1 0 Dppa2/4 conserved region IKI3 PF04762.7 EIW82178.1 - 0.069 10.9 0.0 5.5 4.6 0.0 2.4 2 1 0 2 2 2 0 IKI3 family PQQ_3 PF13570.1 EIW82178.1 - 0.87 9.9 8.2 1.9 8.8 0.0 4.1 5 0 0 5 5 5 0 PQQ-like domain Peptidase_S64 PF08192.6 EIW82182.1 - 0.7 8.1 5.4 0.15 10.3 0.9 1.7 2 0 0 2 2 2 0 Peptidase family S64 EF-hand_1 PF00036.27 EIW82183.1 - 3.4e-27 91.6 9.4 5.6e-06 25.2 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EIW82183.1 - 2e-25 88.7 1.4 5.5e-13 48.8 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EIW82183.1 - 1.1e-21 74.6 5.1 1.8e-05 24.2 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EIW82183.1 - 5.9e-20 69.6 8.8 5e-05 22.4 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EIW82183.1 - 4.2e-16 58.2 9.9 8.8e-05 22.0 0.8 4.6 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_4 PF12763.2 EIW82183.1 - 2.1e-06 27.4 4.5 0.0044 16.7 0.2 3.9 1 1 3 4 4 4 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EIW82183.1 - 5.4e-06 26.4 0.0 0.0072 16.3 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EIW82183.1 - 0.0067 16.3 0.1 1.1 9.2 0.0 2.9 2 1 1 3 3 3 1 EF-hand domain Anthrax-tox_M PF09156.5 EIW82183.1 - 0.11 11.5 0.4 0.47 9.5 0.0 1.8 2 0 0 2 2 2 0 Anthrax toxin lethal factor, middle domain TrmE_N PF10396.4 EIW82184.1 - 1.6e-33 115.0 0.0 3.4e-33 114.0 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 EIW82184.1 - 2.4e-20 72.6 0.8 5.7e-19 68.2 0.1 2.5 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 EIW82184.1 - 2e-16 60.0 0.0 3.9e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EIW82184.1 - 3.5e-05 23.6 0.0 0.00012 21.9 0.0 1.8 1 1 0 1 1 1 1 Dynamin family FeoB_N PF02421.13 EIW82184.1 - 0.00077 18.7 0.0 0.0012 18.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EIW82184.1 - 0.0024 18.3 0.0 0.0045 17.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW82184.1 - 0.0038 16.4 0.0 2.8 7.1 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_17 PF13207.1 EIW82184.1 - 0.0072 17.1 0.0 0.019 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 EIW82184.1 - 0.0077 15.6 0.0 0.32 10.4 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_28 PF13521.1 EIW82184.1 - 0.027 14.4 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIW82184.1 - 0.042 14.1 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 EIW82184.1 - 0.075 12.2 0.0 0.16 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 QRPTase_C PF01729.14 EIW82184.1 - 0.11 12.0 0.0 0.29 10.6 0.0 1.6 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain WD40 PF00400.27 EIW82185.1 - 4e-17 61.3 8.0 3.2e-07 29.9 0.3 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat MBOAT PF03062.14 EIW82188.1 - 4.1e-42 144.4 8.1 7.3e-42 143.6 5.6 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Ribosomal_L18e PF00828.14 EIW82189.1 - 2e-21 76.7 0.0 2e-21 76.7 0.0 2.0 2 1 0 2 2 2 1 Ribosomal protein L18e/L15 RRM_1 PF00076.17 EIW82190.1 - 1.3e-16 59.9 0.0 1.8e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW82190.1 - 3.4e-14 52.5 0.0 5.3e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW82190.1 - 1.2e-13 50.6 0.0 1.8e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 EIW82190.1 - 9.3 5.9 61.4 0.065 12.9 3.2 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1777) p450 PF00067.17 EIW82191.1 - 2.2e-63 214.3 0.0 2.7e-63 214.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase_Tyr PF07714.12 EIW82192.1 - 5.9e-34 117.3 0.0 1.2e-33 116.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EIW82192.1 - 4.6e-33 114.4 0.0 1.1e-32 113.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EIW82192.1 - 0.01 15.6 1.3 0.035 13.8 0.1 2.2 2 1 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.17 EIW82192.1 - 0.077 12.3 0.4 1 8.6 0.0 2.6 3 0 0 3 3 3 0 RIO1 family NDK PF00334.14 EIW82193.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.1 1 0 0 1 1 1 0 Nucleoside diphosphate kinase Adeno_terminal PF02459.10 EIW82193.1 - 0.19 9.8 3.4 0.24 9.5 2.4 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein DUF3722 PF12519.3 EIW82194.1 - 6.6e-94 313.9 0.1 9e-94 313.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 EIW82194.1 - 0.00022 20.6 0.0 7.3 5.8 0.0 3.3 3 0 0 3 3 3 3 Eukaryotic porin DUF2528 PF10800.3 EIW82194.1 - 0.08 13.3 0.0 0.17 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2528) Pkinase PF00069.20 EIW82195.1 - 7.1e-69 231.8 0.0 9.6e-69 231.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW82195.1 - 5e-32 110.9 0.0 1.3e-30 106.4 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW82195.1 - 4.9e-05 22.4 1.5 0.13 11.1 0.4 2.6 2 1 0 2 2 2 2 Kinase-like RIO1 PF01163.17 EIW82195.1 - 0.00079 18.8 0.5 0.0013 18.1 0.3 1.3 1 0 0 1 1 1 1 RIO1 family Mg_trans_NIPA PF05653.9 EIW82196.1 - 1.2e-66 224.7 4.3 8.7e-63 212.0 0.6 2.0 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EIW82196.1 - 2.8e-08 33.9 13.9 5.7e-07 29.7 0.0 3.3 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EIW82196.1 - 0.0001 22.3 1.1 0.0001 22.3 0.7 3.1 3 1 0 3 3 3 1 EamA-like transporter family DUF914 PF06027.7 EIW82196.1 - 0.0087 14.9 0.1 0.44 9.3 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) WD40 PF00400.27 EIW82197.1 - 4.3e-11 42.2 0.1 5.4e-09 35.5 0.0 3.4 3 0 0 3 3 3 1 WD domain, G-beta repeat ATP-synt_8 PF00895.15 EIW82197.1 - 1.1 9.4 9.5 1.9 8.7 0.3 2.6 2 0 0 2 2 2 0 ATP synthase protein 8 TFIID-31kDa PF02291.10 EIW82198.1 - 1.1e-28 99.6 0.0 1.5e-28 99.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.1 EIW82198.1 - 9.8e-05 22.4 0.0 0.00022 21.3 0.0 1.5 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 EIW82198.1 - 0.00075 19.1 0.0 0.0018 17.9 0.0 1.6 2 0 0 2 2 2 1 Bromodomain associated Histone PF00125.19 EIW82198.1 - 0.072 13.2 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Ycf1 PF05758.7 EIW82198.1 - 0.49 8.0 3.4 0.53 7.9 2.3 1.0 1 0 0 1 1 1 0 Ycf1 RRM_1 PF00076.17 EIW82201.1 - 1.2e-26 92.0 0.1 3.8e-12 45.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW82201.1 - 3.9e-20 71.6 0.0 4.9e-09 36.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW82201.1 - 1.2e-07 31.4 0.0 0.0049 16.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EIW82201.1 - 0.051 13.0 1.8 16 5.0 0.4 3.5 2 1 0 2 2 2 0 Ribonuclease B OB domain Limkain-b1 PF11608.3 EIW82201.1 - 0.072 12.8 4.3 0.91 9.3 0.4 3.2 3 0 0 3 3 3 0 Limkain b1 Glyco_hydro_cc PF11790.3 EIW82202.1 - 9.4e-50 169.2 5.4 9.4e-50 169.2 3.7 1.7 1 1 1 2 2 2 1 Glycosyl hydrolase catalytic core Pol_alpha_B_N PF08418.5 EIW82202.1 - 0.011 15.3 1.8 0.013 14.9 1.2 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Ribosomal_L11_N PF03946.9 EIW82205.1 - 8.5e-28 95.5 0.6 1.2e-27 95.1 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EIW82205.1 - 1.2e-26 92.6 0.1 1.9e-26 92.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain WD40 PF00400.27 EIW82206.1 - 6.5e-06 25.8 0.1 0.075 12.9 0.1 3.9 3 0 0 3 3 3 3 WD domain, G-beta repeat WD40 PF00400.27 EIW82208.1 - 9.4e-10 37.9 9.2 0.026 14.3 0.0 4.5 5 0 0 5 5 5 3 WD domain, G-beta repeat C2 PF00168.25 EIW82210.1 - 1.1e-11 44.4 0.0 1.9e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF1237 PF06824.6 EIW82211.1 - 7e-140 466.3 0.3 8.2e-140 466.1 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Aconitase PF00330.15 EIW82213.1 - 1.4e-178 594.1 0.0 1.7e-178 593.8 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EIW82213.1 - 4e-41 140.1 0.0 6.6e-41 139.4 0.0 1.3 1 0 0 1 1 1 1 Aconitase C-terminal domain Sld5 PF05916.6 EIW82214.1 - 5.1e-07 29.9 0.0 7.5e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein PapC_C PF13953.1 EIW82214.1 - 0.0047 16.5 0.0 0.11 12.1 0.0 2.2 2 0 0 2 2 2 1 PapC C-terminal domain Ribosomal_L29e PF01779.12 EIW82215.1 - 8.4e-23 79.9 15.3 8.4e-23 79.9 10.6 1.4 2 0 0 2 2 2 1 Ribosomal L29e protein family NifU_N PF01592.11 EIW82216.1 - 5.8e-50 168.4 0.0 1e-49 167.7 0.0 1.4 1 1 0 1 1 1 1 NifU-like N terminal domain Nop PF01798.13 EIW82217.1 - 3.1e-41 140.1 0.4 5.1e-41 139.4 0.2 1.3 1 0 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 EIW82217.1 - 7e-40 136.3 3.0 7e-40 136.3 2.1 1.8 2 0 0 2 2 2 1 Prp31 C terminal domain NOSIC PF08060.8 EIW82217.1 - 5.3e-20 70.9 0.2 4.4e-19 68.0 0.2 2.2 2 0 0 2 2 2 1 NOSIC (NUC001) domain Latarcin PF10279.4 EIW82217.1 - 0.028 14.5 0.3 0.61 10.3 0.0 3.0 3 0 0 3 3 3 0 Latarcin precursor DUF501 PF04417.7 EIW82217.1 - 0.081 12.7 0.3 0.38 10.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF501) Tctex-1 PF03645.8 EIW82218.1 - 3.6e-09 36.3 0.0 4e-09 36.2 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family PEX11 PF05648.9 EIW82219.1 - 3.9e-11 42.6 9.4 1.1e-06 28.1 0.1 2.7 3 0 0 3 3 3 2 Peroxisomal biogenesis factor 11 (PEX11) Spore_coat_CotO PF14153.1 EIW82219.1 - 0.049 13.0 4.9 0.076 12.4 3.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO Bud13 PF09736.4 EIW82219.1 - 1.2 9.3 9.0 1.6 8.9 4.2 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Zip PF02535.17 EIW82219.1 - 4.2 6.2 6.3 6.3 5.7 4.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF948 PF06103.6 EIW82220.1 - 0.034 13.9 0.0 0.042 13.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DMPK_coil PF08826.5 EIW82220.1 - 0.08 12.8 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 DMPK coiled coil domain like SNARE_assoc PF09335.6 EIW82221.1 - 6e-13 49.0 10.1 1.6e-12 47.6 5.7 2.3 1 1 1 2 2 2 1 SNARE associated Golgi protein HSF_DNA-bind PF00447.12 EIW82222.1 - 3.5e-20 72.1 0.0 6.7e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Pkinase PF00069.20 EIW82223.1 - 1.2e-67 227.8 0.0 1.7e-67 227.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW82223.1 - 6.5e-28 97.4 0.0 5.8e-27 94.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW82223.1 - 1.6e-08 33.9 0.2 0.015 14.3 0.0 3.1 2 1 1 3 3 3 3 Kinase-like Kdo PF06293.9 EIW82223.1 - 0.13 11.2 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW82223.1 - 0.18 11.5 0.0 1.7 8.2 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family MFS_1 PF07690.11 EIW82224.1 - 2.8e-39 134.8 44.2 1.3e-37 129.3 29.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW82224.1 - 4e-12 45.4 23.6 1.5e-10 40.2 5.9 3.6 4 0 0 4 4 4 3 Sugar (and other) transporter DUF3425 PF11905.3 EIW82225.1 - 4.4e-15 55.7 3.9 1.8e-12 47.3 2.7 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EIW82225.1 - 4.4e-09 36.1 5.9 2.1e-08 34.0 4.1 2.0 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIW82225.1 - 0.00045 19.9 5.0 0.0028 17.4 2.8 2.3 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EIW82225.1 - 0.014 15.6 1.2 0.58 10.4 1.2 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor DNA_RNApol_7kD PF03604.8 EIW82227.1 - 5.5e-18 64.1 8.3 6.8e-18 63.8 5.8 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DUF2296 PF10058.4 EIW82227.1 - 0.0015 18.2 0.4 0.044 13.5 0.0 2.2 2 0 0 2 2 2 1 Predicted integral membrane metal-binding protein (DUF2296) DZR PF12773.2 EIW82227.1 - 0.0015 18.2 1.1 0.002 17.8 0.7 1.3 1 0 0 1 1 1 1 Double zinc ribbon HypA PF01155.14 EIW82227.1 - 0.0018 17.9 0.9 0.0021 17.7 0.7 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family zf-ISL3 PF14690.1 EIW82227.1 - 0.002 18.1 2.0 0.01 15.8 0.3 2.0 2 0 0 2 2 2 1 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 zf-C3HC PF07967.8 EIW82227.1 - 0.0083 15.8 0.1 0.0087 15.8 0.1 1.0 1 0 0 1 1 1 1 C3HC zinc finger-like OrfB_Zn_ribbon PF07282.6 EIW82227.1 - 0.0093 15.6 1.6 0.013 15.1 1.1 1.3 1 0 0 1 1 1 1 Putative transposase DNA-binding domain zf-ribbon_3 PF13248.1 EIW82227.1 - 0.01 15.0 0.4 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EIW82227.1 - 0.018 15.0 3.4 0.045 13.7 2.3 1.7 1 1 0 1 1 1 0 Zinc ribbon domain NinF PF05810.7 EIW82227.1 - 0.022 14.5 0.3 0.028 14.2 0.2 1.1 1 0 0 1 1 1 0 NinF protein Zn_ribbon_recom PF13408.1 EIW82227.1 - 0.029 14.6 3.5 0.43 10.8 0.4 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zinc_ribbon_2 PF13240.1 EIW82227.1 - 0.031 13.7 1.4 0.091 12.2 1.0 1.7 1 1 0 1 1 1 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EIW82227.1 - 0.031 13.5 2.8 0.36 10.1 0.1 2.1 1 1 0 2 2 2 0 TFIIB zinc-binding TFIIS_C PF01096.13 EIW82227.1 - 0.042 13.4 1.4 2.4 7.8 0.1 2.2 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) GFA PF04828.9 EIW82227.1 - 0.058 13.3 1.3 2.4 8.1 0.9 2.1 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme zinc_ribbon_5 PF13719.1 EIW82227.1 - 0.093 12.3 2.9 0.84 9.2 2.0 2.1 1 1 0 1 1 1 0 zinc-ribbon domain Mu-like_Com PF10122.4 EIW82227.1 - 0.12 11.4 4.2 2.8 7.0 0.0 2.2 1 1 1 2 2 2 0 Mu-like prophage protein Com zf-Sec23_Sec24 PF04810.10 EIW82227.1 - 0.14 11.7 2.3 3.3 7.3 1.0 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger DUF2318 PF10080.4 EIW82227.1 - 0.14 11.9 0.6 0.18 11.5 0.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Zn_Tnp_IS1595 PF12760.2 EIW82227.1 - 0.2 11.4 3.9 0.6 9.9 2.6 1.7 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-NADH-PPase PF09297.6 EIW82227.1 - 0.21 11.0 3.2 1 8.9 2.2 2.0 1 1 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain zinc_ribbon_4 PF13717.1 EIW82227.1 - 0.23 11.2 3.6 3.2 7.5 2.5 2.1 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_6 PF14599.1 EIW82227.1 - 0.25 11.1 1.5 1.3 8.9 1.1 1.9 1 1 1 2 2 2 0 Zinc-ribbon Ogr_Delta PF04606.7 EIW82227.1 - 0.34 10.5 2.4 6 6.6 0.2 2.2 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-trcl PF13451.1 EIW82227.1 - 0.48 10.0 6.7 3 7.5 1.0 2.2 1 1 1 2 2 2 0 Probable zinc-binding domain Ribosomal_L37e PF01907.14 EIW82227.1 - 0.52 10.1 4.5 8.6 6.2 1.6 2.1 1 1 1 2 2 2 0 Ribosomal protein L37e Cas_CXXC_CXXC PF09706.5 EIW82227.1 - 0.53 10.5 4.1 10 6.3 0.2 2.1 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_CXXC_CXXC) DUF35_N PF12172.3 EIW82227.1 - 0.71 9.8 3.2 4.1 7.4 0.6 2.4 2 1 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) A2L_zn_ribbon PF08792.5 EIW82227.1 - 0.75 9.3 3.6 4.6 6.8 0.2 2.0 1 1 0 2 2 2 0 A2L zinc ribbon domain RRN7 PF11781.3 EIW82227.1 - 0.8 9.2 4.1 8.4 5.9 0.7 2.2 1 1 1 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DUF2197 PF09963.4 EIW82227.1 - 0.91 9.5 4.5 28 4.7 2.9 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) UPF0547 PF10571.4 EIW82227.1 - 1.2 8.9 4.6 2.1 8.1 0.6 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 YhfH PF14149.1 EIW82227.1 - 3.6 7.4 5.8 6.9 6.5 0.3 2.2 1 1 1 2 2 2 0 YhfH-like protein Barttin PF15462.1 EIW82228.1 - 0.17 11.4 6.4 0.24 11.0 4.5 1.2 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) DUF4187 PF13821.1 EIW82229.1 - 9e-19 66.8 0.2 1.8e-18 65.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EIW82229.1 - 3.8e-05 23.3 4.6 0.00047 19.8 3.2 2.5 1 1 0 1 1 1 1 G-patch domain Pkr1 PF08636.5 EIW82230.1 - 5.8e-16 58.3 3.8 7.3e-16 57.9 2.7 1.1 1 0 0 1 1 1 1 ER protein Pkr1 Phage_Gp23 PF10669.4 EIW82230.1 - 0.062 13.4 0.1 0.082 13.0 0.1 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Tau95 PF09734.4 EIW82231.1 - 7.6e-66 222.5 0.0 1e-65 222.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit LSM PF01423.17 EIW82232.1 - 9e-17 60.3 0.0 1e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 LSM domain Cas_NE0113 PF09623.5 EIW82232.1 - 0.075 12.4 0.0 0.091 12.2 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein NE0113 (Cas_NE0113) TPMT PF05724.6 EIW82233.1 - 1.2e-29 103.3 0.0 1.5e-29 103.0 0.0 1.1 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 EIW82233.1 - 7.4e-06 26.5 0.0 1.1e-05 25.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW82233.1 - 1.6e-05 25.3 0.0 2.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW82233.1 - 2.2e-05 24.1 0.0 2.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW82233.1 - 8e-05 22.4 0.0 0.00012 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW82233.1 - 8.1e-05 22.6 0.0 0.00018 21.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW82233.1 - 0.00013 22.2 0.0 0.00017 21.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW82233.1 - 0.00015 22.1 0.0 0.00021 21.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EIW82233.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.4 1 1 0 1 1 1 0 Tellurite resistance protein TehB Peptidase_M22 PF00814.20 EIW82234.1 - 0.0098 15.4 0.0 0.015 14.8 0.0 1.3 1 0 0 1 1 1 1 Glycoprotease family AAA PF00004.24 EIW82235.1 - 4.6e-32 111.0 0.0 6.7e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIW82235.1 - 7.4e-09 35.8 0.1 4.9e-08 33.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW82235.1 - 4.7e-07 30.6 0.0 1.1e-06 29.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW82235.1 - 1.6e-06 28.2 0.2 1.3e-05 25.2 0.2 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EIW82235.1 - 4e-06 27.1 0.0 6.9e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW82235.1 - 8.8e-06 25.6 0.0 2e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EIW82235.1 - 1.6e-05 24.8 0.0 2.5e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW82235.1 - 3.1e-05 23.6 0.1 0.00043 19.9 0.0 2.6 3 0 0 3 3 2 1 Part of AAA domain AAA_25 PF13481.1 EIW82235.1 - 3.2e-05 23.4 0.2 0.069 12.5 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.9 EIW82235.1 - 3.5e-05 23.7 0.0 5.8e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Arch_ATPase PF01637.13 EIW82235.1 - 6.5e-05 22.7 0.2 0.0049 16.5 0.1 2.2 1 1 0 1 1 1 1 Archaeal ATPase AAA_11 PF13086.1 EIW82235.1 - 9.4e-05 22.0 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EIW82235.1 - 0.0002 20.4 0.0 0.027 13.4 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) KAP_NTPase PF07693.9 EIW82235.1 - 0.00021 20.3 0.1 0.1 11.5 0.0 2.2 1 1 1 2 2 2 2 KAP family P-loop domain UPF0079 PF02367.12 EIW82235.1 - 0.00043 19.9 0.0 0.00085 18.9 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_5 PF07728.9 EIW82235.1 - 0.0011 18.7 0.2 0.0041 16.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EIW82235.1 - 0.0016 18.6 0.0 0.005 16.9 0.0 1.9 2 0 0 2 2 1 1 RNA helicase AAA_24 PF13479.1 EIW82235.1 - 0.0018 17.8 0.0 0.0046 16.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EIW82235.1 - 0.002 18.1 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EIW82235.1 - 0.0024 17.3 0.0 0.0069 15.8 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein RuvB_N PF05496.7 EIW82235.1 - 0.0025 16.8 0.0 0.0054 15.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 EIW82235.1 - 0.0028 17.2 0.0 0.0052 16.3 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase TIP49 PF06068.8 EIW82235.1 - 0.0028 16.4 0.0 0.0038 15.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus NACHT PF05729.7 EIW82235.1 - 0.0031 17.1 0.1 0.0071 16.0 0.0 1.8 1 1 0 1 1 1 1 NACHT domain AAA_30 PF13604.1 EIW82235.1 - 0.0074 15.8 0.0 0.024 14.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EIW82235.1 - 0.0084 15.1 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 EIW82235.1 - 0.015 15.5 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 EIW82235.1 - 0.024 13.7 0.0 0.047 12.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.16 EIW82235.1 - 0.038 13.1 0.0 0.093 11.8 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EIW82235.1 - 0.043 13.0 0.0 0.2 10.8 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein MobB PF03205.9 EIW82235.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_3 PF07726.6 EIW82235.1 - 0.05 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_13 PF13166.1 EIW82235.1 - 0.06 11.8 0.0 0.088 11.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EIW82235.1 - 0.092 12.7 0.1 0.38 10.8 0.1 2.0 1 1 1 2 2 2 0 Sigma-54 interaction domain CPT PF07931.7 EIW82235.1 - 0.1 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein KaiC PF06745.8 EIW82235.1 - 0.11 11.6 0.1 1.6 7.8 0.0 2.1 1 1 0 2 2 2 0 KaiC NTPase_1 PF03266.10 EIW82235.1 - 0.12 12.1 0.1 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 NTPase PduV-EutP PF10662.4 EIW82235.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.21 EIW82235.1 - 0.16 11.4 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.1 EIW82235.1 - 0.17 12.1 0.0 0.41 10.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain Rdx PF10262.4 EIW82236.1 - 1.6e-23 82.5 0.0 1.9e-23 82.2 0.0 1.1 1 0 0 1 1 1 1 Rdx family CLASP_N PF12348.3 EIW82237.1 - 5.5e-71 238.5 2.9 4.7e-68 228.9 0.1 3.7 4 1 1 5 5 5 2 CLASP N terminal HEAT PF02985.17 EIW82237.1 - 1.9e-10 39.9 0.5 0.65 10.2 0.0 6.5 6 0 0 6 6 6 3 HEAT repeat Cohesin_HEAT PF12765.2 EIW82237.1 - 0.00013 21.8 0.3 0.58 10.1 0.0 3.7 4 0 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.1 EIW82237.1 - 0.0058 17.0 5.5 2 9.0 0.0 5.4 5 1 0 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.1 EIW82237.1 - 0.089 13.0 15.3 11 6.4 0.0 6.4 7 1 0 7 7 7 0 HEAT repeats RNA_pol_Rpb6 PF01192.17 EIW82237.1 - 0.096 12.4 1.1 0.3 10.8 0.7 1.8 1 0 0 1 1 1 0 RNA polymerase Rpb6 Adaptin_N PF01602.15 EIW82237.1 - 0.22 9.8 0.0 2 6.6 0.0 2.6 3 0 0 3 3 3 0 Adaptin N terminal region Peptidase_M28 PF04389.12 EIW82238.1 - 4.3e-28 98.2 0.8 9.1e-28 97.1 0.5 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M42 PF05343.9 EIW82238.1 - 0.0097 14.6 0.0 0.017 13.9 0.0 1.4 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Rhomboid PF01694.17 EIW82239.1 - 3.8e-21 75.6 3.9 4.5e-21 75.4 2.7 1.0 1 0 0 1 1 1 1 Rhomboid family EBP PF05241.7 EIW82239.1 - 0.0081 15.1 0.3 0.76 8.7 0.0 2.1 2 0 0 2 2 2 2 Emopamil binding protein Sedlin_N PF04628.8 EIW82240.1 - 1.5e-37 128.3 0.0 2.1e-37 127.9 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EIW82240.1 - 2.5e-06 27.2 0.0 3.6e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Sybindin-like family AIP3 PF03915.8 EIW82241.1 - 8.5 5.1 10.8 12 4.6 7.5 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 Actin PF00022.14 EIW82242.1 - 2.9e-113 378.2 0.0 3.3e-113 378.0 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EIW82242.1 - 1.8e-05 23.5 0.0 0.044 12.3 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein BOP1NT PF08145.7 EIW82243.1 - 1.5e-98 329.7 6.3 2.1e-98 329.2 4.4 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EIW82243.1 - 8.4e-25 85.7 6.0 7.3e-08 32.0 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat SDA1 PF05285.7 EIW82243.1 - 0.036 13.3 16.2 0.053 12.8 11.2 1.3 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 EIW82243.1 - 1.1 7.6 21.1 1.6 7.0 14.6 1.2 1 0 0 1 1 1 0 Daxx Family SAPS PF04499.10 EIW82243.1 - 3.4 6.2 4.6 4.8 5.7 3.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF1510 PF07423.6 EIW82243.1 - 3.5 6.9 16.0 6.4 6.0 11.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Paf1 PF03985.8 EIW82243.1 - 3.9 6.0 14.5 6.7 5.3 10.0 1.2 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.7 EIW82243.1 - 4.3 5.1 26.4 6.1 4.6 18.3 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2423 PF10338.4 EIW82245.1 - 2.8e-14 52.8 6.7 5.6e-14 51.8 4.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2423) LSM PF01423.17 EIW82246.1 - 1.3e-20 72.6 0.0 1.5e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EIW82246.1 - 0.0029 17.4 0.0 0.0031 17.3 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain CBFD_NFYB_HMF PF00808.18 EIW82247.1 - 2.2e-19 69.2 0.6 3.7e-19 68.5 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Terpene_synth PF01397.16 EIW82247.1 - 0.0013 18.1 0.8 0.0015 17.9 0.6 1.2 1 0 0 1 1 1 1 Terpene synthase, N-terminal domain Histone PF00125.19 EIW82247.1 - 0.0065 16.5 0.2 0.014 15.5 0.0 1.7 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EIW82247.1 - 0.053 13.2 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated TFIID-18kDa PF02269.11 EIW82247.1 - 0.055 13.2 0.5 0.13 12.1 0.2 1.8 1 1 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit PfkB PF00294.19 EIW82248.1 - 1e-20 74.0 0.0 2.1e-20 73.0 0.0 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EIW82248.1 - 0.00066 18.9 0.0 0.00094 18.4 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase ACPS PF01648.15 EIW82249.1 - 1.5e-11 44.1 0.0 3.9e-11 42.7 0.0 1.6 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily tRNA-synt_2 PF00152.15 EIW82250.1 - 2.2e-102 342.2 0.0 5.1e-102 341.0 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EIW82250.1 - 3e-06 27.0 0.0 5.6e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 EIW82250.1 - 0.00012 21.7 0.1 0.14 11.7 0.1 3.1 2 1 0 3 3 3 2 tRNA synthetase class II core domain (G, H, P, S and T) Ribosomal_L19 PF01245.15 EIW82251.1 - 2.5e-16 59.4 0.0 3.8e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 Reeler PF02014.11 EIW82251.1 - 0.16 12.2 0.0 0.23 11.6 0.0 1.2 1 0 0 1 1 1 0 Reeler domain RRM_1 PF00076.17 EIW82252.1 - 1.7e-17 62.8 0.0 3.1e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW82252.1 - 1.2e-14 54.0 0.0 2.6e-14 52.9 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW82252.1 - 4.3e-06 26.4 0.0 9.4e-06 25.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Fungal_trans PF04082.13 EIW82253.1 - 5.3e-39 133.6 0.0 8.4e-39 132.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW82253.1 - 2.8e-08 33.5 15.8 5.6e-08 32.5 11.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NB PF04159.8 EIW82253.1 - 1.2 8.9 2.9 2.7 7.7 2.0 1.5 1 0 0 1 1 1 0 NB glycoprotein Acyl-CoA_dh_1 PF00441.19 EIW82254.1 - 2e-31 109.1 0.5 3.2e-31 108.4 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EIW82254.1 - 7e-15 54.2 0.0 1.5e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EIW82254.1 - 5.8e-14 52.4 0.4 1.1e-13 51.5 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EIW82254.1 - 3.8e-11 43.5 0.0 1.3e-10 41.8 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain DUF3752 PF12572.3 EIW82255.1 - 0.00014 22.0 2.0 0.0044 17.1 0.8 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF3752) MRP-S26 PF14943.1 EIW82255.1 - 0.43 10.1 0.0 0.43 10.1 0.0 2.3 2 1 1 3 3 3 0 Mitochondrial ribosome subunit S26 Suc_Fer-like PF06999.7 EIW82256.1 - 2.1e-37 129.3 0.1 5.5e-37 128.0 0.1 1.7 1 1 0 1 1 1 1 Sucrase/ferredoxin-like CIAPIN1 PF05093.8 EIW82257.1 - 1.5e-29 101.9 4.2 2.7e-29 101.2 2.9 1.3 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Fork_head PF00250.13 EIW82258.1 - 3.6e-30 103.8 0.0 6.8e-30 102.9 0.0 1.3 1 0 0 1 1 1 1 Fork head domain Pkinase PF00069.20 EIW82260.1 - 2.3e-69 233.4 0.0 3.1e-69 233.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW82260.1 - 4.4e-30 104.6 0.0 6.3e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EIW82260.1 - 8.6e-13 48.5 3.3 8.6e-13 48.5 2.3 3.1 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EIW82260.1 - 2.5e-09 36.5 0.0 3.3e-08 32.8 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EIW82260.1 - 0.0024 17.6 0.0 0.0043 16.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family C2 PF00168.25 EIW82260.1 - 0.0032 17.2 0.1 2.5 8.0 0.0 2.5 2 0 0 2 2 2 2 C2 domain Kdo PF06293.9 EIW82260.1 - 0.018 14.1 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cyt-b5 PF00173.23 EIW82261.1 - 1.2e-24 85.8 0.0 1.8e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HIG_1_N PF04588.8 EIW82262.1 - 6.2e-06 25.8 0.3 1.1e-05 25.0 0.2 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Phenol_Hydrox PF02332.13 EIW82262.1 - 0.005 16.1 0.2 0.0085 15.4 0.1 1.3 1 1 0 1 1 1 1 Methane/Phenol/Toluene Hydroxylase Nucleoporin2 PF04096.9 EIW82263.1 - 2.4e-42 144.0 0.0 3.7e-42 143.4 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EIW82263.1 - 3.3e-14 53.0 170.0 1e-08 35.4 25.2 9.9 2 1 6 8 8 8 6 Nucleoporin FG repeat region RNA_pol_Rpb2_6 PF00562.23 EIW82264.1 - 5e-115 384.3 0.1 6.5e-115 383.9 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EIW82264.1 - 9.7e-29 99.7 0.0 1.4e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 EIW82264.1 - 1.7e-26 91.7 0.0 3.7e-26 90.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 EIW82264.1 - 4.7e-22 77.6 0.0 1e-21 76.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.9 EIW82264.1 - 2e-21 76.2 0.0 3.7e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EIW82264.1 - 1.3e-17 63.8 0.0 4.7e-16 58.8 0.0 2.8 2 1 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EIW82264.1 - 0.099 12.6 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 zf-C2H2 PF00096.21 EIW82266.1 - 1.4 9.4 7.9 3 8.3 0.2 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type Methyltransf_23 PF13489.1 EIW82267.1 - 4e-13 49.3 0.0 7.2e-13 48.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW82267.1 - 1.4e-09 38.3 0.0 3.3e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW82267.1 - 1.6e-07 30.9 0.0 2.7e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW82267.1 - 2.5e-07 31.0 0.0 5.9e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW82267.1 - 0.00014 22.4 0.0 0.00038 21.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 EIW82267.1 - 0.03 14.0 0.0 0.048 13.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GHMP_kinases_C PF08544.8 EIW82267.1 - 0.034 14.3 0.0 13 6.0 0.0 2.6 2 0 0 2 2 2 0 GHMP kinases C terminal MTS PF05175.9 EIW82267.1 - 0.035 13.4 0.0 0.056 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.1 EIW82267.1 - 0.036 14.4 0.0 0.11 12.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EIW82267.1 - 0.088 11.7 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 NNMT/PNMT/TEMT family Methyltransf_PK PF05891.7 EIW82267.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase RRM_1 PF00076.17 EIW82268.1 - 0.0021 17.6 0.1 7.2 6.3 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_3 PF00933.16 EIW82269.1 - 1.1e-48 165.8 0.1 1.7e-48 165.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIW82269.1 - 2.6e-44 151.4 0.0 1.1e-42 146.1 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIW82269.1 - 2.2e-24 85.1 0.1 5.7e-24 83.8 0.1 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EIW82269.1 - 5.8e-09 35.7 0.0 1.2e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 PA14 domain RNA_pol_L PF01193.19 EIW82269.1 - 0.13 11.4 0.0 1.2 8.2 0.0 2.1 2 1 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain zf-C3HC4_2 PF13923.1 EIW82270.1 - 7.3e-08 32.3 22.8 2.2e-07 30.7 11.5 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW82270.1 - 6.5e-07 28.9 20.0 0.00019 21.0 8.6 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW82270.1 - 0.00022 20.9 27.0 0.00042 20.0 11.6 3.2 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EIW82270.1 - 0.0003 20.3 14.4 0.0003 20.3 10.0 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW82270.1 - 0.0004 20.0 21.1 0.00089 18.9 9.1 3.2 3 0 0 3 3 3 1 zinc-RING finger domain PRP21_like_P PF12230.3 EIW82270.1 - 0.22 11.0 5.9 1.5 8.2 0.2 2.7 3 0 0 3 3 3 0 Pre-mRNA splicing factor PRP21 like protein zf-RING_6 PF14835.1 EIW82270.1 - 1.1 9.0 14.5 0.69 9.7 6.6 2.9 3 0 0 3 3 3 0 zf-RING of BARD1-type protein Rad50_zn_hook PF04423.9 EIW82270.1 - 3 7.3 7.6 2.1 7.9 0.0 3.4 3 0 0 3 3 3 0 Rad50 zinc hook motif GAGA PF09237.6 EIW82270.1 - 3.6 7.2 9.8 10 5.7 0.1 4.3 4 0 0 4 4 4 0 GAGA factor zf-Di19 PF05605.7 EIW82270.1 - 5.8 7.1 13.3 14 5.8 0.0 4.0 3 1 1 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding JAB PF01398.16 EIW82271.1 - 3.6e-20 71.7 0.1 6.9e-20 70.9 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EIW82271.1 - 2.2e-13 50.2 0.1 4.3e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Caleosin PF05042.8 EIW82271.1 - 0.046 13.2 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 Caleosin related protein KicB PF03882.9 EIW82271.1 - 0.086 11.4 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 KicB killing factor UreF PF01730.11 EIW82272.1 - 1.1e-13 51.5 0.1 1.5e-13 51.0 0.1 1.2 1 0 0 1 1 1 1 UreF CTP_transf_3 PF02348.14 EIW82272.1 - 0.045 13.3 0.0 0.069 12.7 0.0 1.2 1 0 0 1 1 1 0 Cytidylyltransferase AFG1_ATPase PF03969.11 EIW82273.1 - 4e-98 328.5 0.0 1.4e-94 316.8 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EIW82273.1 - 0.00063 19.7 0.1 0.13 12.2 0.0 2.5 1 1 1 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EIW82273.1 - 0.0031 17.6 0.1 0.022 14.9 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 EIW82273.1 - 0.0044 17.2 0.0 0.024 14.8 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SBDS PF01172.13 EIW82274.1 - 1.2e-16 60.2 0.1 1.4e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein HATPase_c_3 PF13589.1 EIW82275.1 - 4.3e-09 36.1 0.1 1.1e-08 34.8 0.0 1.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 EIW82275.1 - 2.5e-08 33.3 0.0 4.9e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.21 EIW82275.1 - 4.5e-07 29.5 0.0 8.7e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 EIW82275.1 - 0.00012 21.7 0.0 0.0017 17.9 0.0 2.5 2 0 0 2 2 2 1 MutL C terminal dimerisation domain Carboxyl_trans PF01039.17 EIW82276.1 - 1.2e-141 472.4 0.7 1.5e-141 472.1 0.5 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EIW82276.1 - 0.00019 20.6 0.2 0.29 10.3 0.0 2.4 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) ArfGap PF01412.13 EIW82277.1 - 1.4e-33 115.1 0.1 2.4e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf Velvet PF11754.3 EIW82278.1 - 1.4e-26 93.3 0.0 9.7e-26 90.6 0.0 2.0 1 1 0 1 1 1 1 Velvet factor DUF2457 PF10446.4 EIW82278.1 - 0.017 13.8 0.6 0.028 13.1 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PPR_2 PF13041.1 EIW82279.1 - 6.7e-40 134.8 2.6 2.5e-06 27.3 0.0 11.8 9 2 4 13 13 13 7 PPR repeat family PPR_3 PF13812.1 EIW82279.1 - 1.7e-31 105.7 11.5 0.00058 19.9 0.0 14.8 16 0 0 16 16 16 7 Pentatricopeptide repeat domain PPR PF01535.15 EIW82279.1 - 3.6e-30 101.8 8.3 0.003 17.4 0.0 14.5 16 0 0 16 16 16 7 PPR repeat PPR_1 PF12854.2 EIW82279.1 - 2.7e-13 49.1 0.4 0.00092 18.6 0.0 8.3 10 0 0 10 10 10 2 PPR repeat TPR_14 PF13428.1 EIW82279.1 - 5.2e-06 26.6 14.5 26 5.8 0.2 9.6 8 1 2 10 10 10 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIW82279.1 - 0.018 15.7 8.9 11 6.8 0.1 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat B12-binding_2 PF02607.12 EIW82279.1 - 0.046 13.7 0.1 9.4 6.3 0.0 3.5 3 0 0 3 3 3 0 B12 binding domain M16C_assoc PF08367.6 EIW82279.1 - 0.22 10.3 0.0 2.2 7.0 0.0 2.3 2 0 0 2 2 2 0 Peptidase M16C associated Acetyltransf_1 PF00583.19 EIW82280.1 - 0.00014 21.7 0.0 0.00026 20.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIW82280.1 - 0.0002 21.4 0.0 0.00029 20.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 EIW82280.1 - 0.0033 17.9 0.0 0.26 11.8 0.0 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIW82280.1 - 0.056 13.5 0.0 0.07 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HMG_box_2 PF09011.5 EIW82281.1 - 1.1e-15 57.7 13.6 4.8e-08 33.2 3.1 2.6 2 1 0 2 2 2 2 HMG-box domain HMG_box PF00505.14 EIW82281.1 - 1.3e-14 54.2 18.0 5.2e-07 29.8 4.0 3.3 2 1 0 2 2 2 2 HMG (high mobility group) box Herpes_TK PF00693.13 EIW82281.1 - 0.067 12.3 0.2 0.1 11.7 0.1 1.3 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus DUF1074 PF06382.6 EIW82281.1 - 0.18 11.7 4.2 0.044 13.7 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1074) GRIM-19 PF06212.7 EIW82283.1 - 6e-29 100.3 0.0 7e-29 100.1 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein SlyX PF04102.7 EIW82284.1 - 0.0032 17.8 0.8 0.01 16.1 0.5 1.9 1 0 0 1 1 1 1 SlyX Fer4 PF00037.22 EIW82285.1 - 5.4e-14 51.1 17.4 1.7e-08 33.7 3.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EIW82285.1 - 2.5e-12 46.9 10.8 4e-12 46.3 7.5 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EIW82285.1 - 2.3e-10 40.1 22.2 1.1e-08 34.7 8.3 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.1 EIW82285.1 - 4.3e-10 40.1 18.8 9.3e-07 29.4 7.4 2.2 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 EIW82285.1 - 6.7e-10 38.6 4.8 0.0001 22.0 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EIW82285.1 - 2.3e-09 37.3 11.2 4e-09 36.5 7.8 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EIW82285.1 - 6.1e-09 35.7 18.6 8.8e-06 25.6 7.8 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 EIW82285.1 - 2.5e-08 33.3 15.2 6.9e-05 22.5 1.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_6 PF12837.2 EIW82285.1 - 7.4e-08 31.9 18.0 0.00072 19.3 3.4 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EIW82285.1 - 1.4e-07 31.6 26.2 0.00017 21.8 7.1 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_4 PF12800.2 EIW82285.1 - 1.2e-06 28.3 11.1 0.00036 20.6 1.6 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_18 PF13746.1 EIW82285.1 - 6.2e-06 26.5 8.5 0.0088 16.4 0.3 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EIW82285.1 - 0.00038 20.7 12.6 0.054 13.9 0.7 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EIW82285.1 - 0.0025 18.3 12.1 0.22 12.1 0.9 2.7 2 1 0 2 2 2 2 4Fe-4S single cluster domain c-SKI_SMAD_bind PF08782.5 EIW82285.1 - 0.015 15.4 4.2 0.035 14.2 0.1 2.2 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_3 PF12798.2 EIW82285.1 - 0.041 14.4 18.1 0.077 13.5 3.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Prefoldin_2 PF01920.15 EIW82286.1 - 1.9e-21 75.8 1.8 2.2e-21 75.6 1.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit Taxilin PF09728.4 EIW82286.1 - 0.0086 15.2 0.5 1.9 7.5 0.0 2.1 2 0 0 2 2 2 2 Myosin-like coiled-coil protein PhoU_div PF01865.11 EIW82286.1 - 0.0099 15.0 0.3 1.4 8.0 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function DUF47 IncA PF04156.9 EIW82286.1 - 0.021 14.4 3.0 0.18 11.3 1.2 1.9 2 0 0 2 2 2 0 IncA protein DUF148 PF02520.12 EIW82286.1 - 0.036 13.8 1.7 1 9.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF148 DASH_Dad3 PF08656.5 EIW82286.1 - 0.051 13.2 0.6 0.17 11.6 0.2 1.8 2 0 0 2 2 2 0 DASH complex subunit Dad3 Gp-FAR-1 PF05823.7 EIW82286.1 - 0.056 13.4 0.3 0.094 12.6 0.2 1.3 1 1 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF4407 PF14362.1 EIW82286.1 - 0.058 12.3 1.3 0.089 11.7 0.9 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_1 PF00170.16 EIW82286.1 - 0.073 13.0 0.3 3.3 7.7 0.0 2.2 2 0 0 2 2 2 0 bZIP transcription factor Toxin_52 PF15605.1 EIW82286.1 - 0.1 12.4 0.8 4.4 7.2 0.1 2.2 2 0 0 2 2 2 0 Putative toxin 52 Cytochrom_B562 PF07361.6 EIW82286.1 - 0.12 12.8 2.7 2.2 8.7 0.2 2.1 2 0 0 2 2 2 0 Cytochrome b562 FKBP_N PF01346.13 EIW82286.1 - 0.13 12.2 2.7 2.4 8.2 0.3 2.2 2 1 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase Prefoldin PF02996.12 EIW82286.1 - 0.14 11.8 2.7 3 7.5 1.9 2.1 1 1 0 1 1 1 0 Prefoldin subunit DivIVA PF05103.8 EIW82286.1 - 0.16 12.0 3.4 0.62 10.1 0.2 2.0 2 0 0 2 2 2 0 DivIVA protein Tropomyosin_1 PF12718.2 EIW82286.1 - 0.18 11.6 5.3 0.98 9.2 1.2 2.1 2 0 0 2 2 2 0 Tropomyosin like WXG100 PF06013.7 EIW82286.1 - 0.18 11.8 1.2 2.7 8.0 0.2 2.1 2 0 0 2 2 2 0 Proteins of 100 residues with WXG BLOC1_2 PF10046.4 EIW82286.1 - 0.19 11.8 2.2 2.1 8.5 0.2 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TACC PF05010.9 EIW82286.1 - 0.26 10.9 2.9 0.3 10.8 0.1 1.9 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC) Tho2 PF11262.3 EIW82286.1 - 0.33 9.9 1.3 3.2 6.7 0.1 2.0 1 1 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Kinetocho_Slk19 PF12709.2 EIW82286.1 - 0.34 11.0 2.8 1.2 9.2 0.0 2.2 2 0 0 2 2 2 0 Central kinetochore-associated Trigger_C PF05698.9 EIW82286.1 - 0.34 10.7 4.4 0.7 9.7 3.1 1.6 1 1 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus Zwint PF15556.1 EIW82286.1 - 0.42 9.8 5.8 0.073 12.3 1.3 1.6 2 0 0 2 2 2 0 ZW10 interactor 60KD_IMP PF02096.15 EIW82286.1 - 0.6 9.7 2.1 2.3 7.8 0.2 2.0 2 0 0 2 2 2 0 60Kd inner membrane protein OmpH PF03938.9 EIW82286.1 - 0.96 9.3 4.8 2.3 8.1 3.3 1.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) CAP PF00188.21 EIW82287.1 - 1e-16 61.5 0.3 1.3e-16 61.1 0.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family ILVD_EDD PF00920.16 EIW82287.1 - 0.048 12.0 0.0 0.064 11.6 0.0 1.3 1 1 0 1 1 1 0 Dehydratase family F-box PF00646.28 EIW82288.1 - 4.6e-06 26.1 1.0 1.3e-05 24.6 0.7 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW82288.1 - 4.9e-05 22.9 0.7 0.00015 21.4 0.5 1.9 1 0 0 1 1 1 1 F-box-like UCH PF00443.24 EIW82289.1 - 3e-37 128.1 0.0 4.6e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW82289.1 - 5.4e-16 58.8 0.0 1.1e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EIW82289.1 - 0.025 13.8 0.2 0.57 9.4 0.1 2.4 1 1 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Josephin PF02099.12 EIW82289.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Josephin DNA_RNApol_7kD PF03604.8 EIW82289.1 - 0.38 10.2 3.4 11 5.5 0.3 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit PP2C PF00481.16 EIW82290.1 - 9.4e-11 41.5 0.0 1.1e-06 28.2 0.0 2.2 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EIW82290.1 - 0.0059 16.0 0.0 0.013 14.9 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C DUF2914 PF11141.3 EIW82290.1 - 0.11 12.0 1.0 0.46 10.0 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2914) ACT_7 PF13840.1 EIW82292.1 - 1.3e-19 69.5 0.0 7.5e-12 44.6 0.0 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 EIW82292.1 - 0.0016 17.8 0.0 0.42 10.1 0.0 2.8 2 0 0 2 2 2 2 ACT domain adh_short PF00106.20 EIW82293.1 - 1.4e-29 103.1 0.2 3.8e-29 101.7 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW82293.1 - 1.8e-12 47.2 0.5 3e-11 43.3 0.4 2.1 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIW82293.1 - 1.4e-06 28.2 0.0 1.9e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIW82293.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.7 1 1 0 1 1 1 0 NADH(P)-binding SKN1 PF03935.10 EIW82295.1 - 4.1e-176 586.0 5.2 4.6e-176 585.8 3.6 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Pex14_N PF04695.8 EIW82296.1 - 1.8e-07 31.2 0.0 1.8e-07 31.2 0.0 3.1 3 2 1 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Rootletin PF15035.1 EIW82296.1 - 0.065 13.2 0.8 0.1 12.5 0.6 1.3 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Fun_ATP-synt_8 PF05933.8 EIW82296.1 - 0.095 12.7 0.5 0.18 11.8 0.3 1.4 1 0 0 1 1 1 0 Fungal ATP synthase protein 8 (A6L) PA PF02225.17 EIW82297.1 - 5.6e-08 32.3 0.1 1e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 PA domain Peptidase_M28 PF04389.12 EIW82298.1 - 4.3e-14 52.6 0.0 8.3e-14 51.7 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EIW82298.1 - 0.00028 20.4 0.0 0.00053 19.5 0.0 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 EIW82298.1 - 0.022 14.0 0.4 0.06 12.5 0.0 1.8 2 0 0 2 2 2 0 Nicastrin TFR_dimer PF04253.10 EIW82299.1 - 1.4e-11 44.0 0.1 2.9e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 Transferrin receptor-like dimerisation domain DUF4170 PF13773.1 EIW82300.1 - 0.0052 16.6 0.0 0.0079 16.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4170) HIG_1_N PF04588.8 EIW82300.1 - 0.094 12.4 0.3 0.43 10.3 0.1 1.9 2 0 0 2 2 2 0 Hypoxia induced protein conserved region Pro-kuma_activ PF09286.6 EIW82301.1 - 3.8e-45 153.4 0.1 7.3e-45 152.5 0.1 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIW82301.1 - 2.2e-08 33.6 4.2 1.9e-07 30.5 2.7 2.2 2 0 0 2 2 2 1 Subtilase family DUF3848 PF12959.2 EIW82302.1 - 0.0024 17.7 1.1 0.0047 16.8 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3848) DUF904 PF06005.7 EIW82302.1 - 0.32 11.3 10.1 2.3 8.5 0.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) TSC22 PF01166.13 EIW82302.1 - 0.38 10.7 5.3 5.7 6.9 0.3 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family bZIP_1 PF00170.16 EIW82302.1 - 0.45 10.5 4.6 14 5.6 0.3 2.7 2 0 0 2 2 2 0 bZIP transcription factor Takusan PF04822.8 EIW82302.1 - 0.59 9.9 7.7 0.18 11.5 2.8 2.0 2 0 0 2 2 2 0 Takusan TBPIP PF07106.8 EIW82302.1 - 0.68 9.4 7.4 0.19 11.2 1.8 2.0 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) bZIP_2 PF07716.10 EIW82302.1 - 0.76 9.6 4.9 1 9.2 0.3 2.6 2 0 0 2 2 2 0 Basic region leucine zipper IncA PF04156.9 EIW82302.1 - 1.7 8.1 7.3 2.9 7.4 5.1 1.3 1 0 0 1 1 1 0 IncA protein SKN1 PF03935.10 EIW82303.1 - 1e-182 607.8 4.1 1.2e-182 607.6 2.8 1.0 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) GTP_cyclohydro2 PF00925.15 EIW82304.1 - 1.7e-61 206.3 0.0 3.1e-56 189.2 0.0 2.2 2 0 0 2 2 2 2 GTP cyclohydrolase II Vps5 PF09325.5 EIW82305.1 - 3.3e-20 72.3 0.8 4.4e-20 71.9 0.6 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EIW82305.1 - 2.8e-12 46.4 0.8 4.1e-12 45.8 0.0 1.7 2 0 0 2 2 2 1 PX domain TPR_12 PF13424.1 EIW82305.1 - 0.0015 18.4 3.7 0.34 10.8 0.1 3.9 3 1 0 3 3 3 1 Tetratricopeptide repeat UPF0081 PF03652.10 EIW82305.1 - 0.057 13.5 0.0 1.5 8.9 0.0 2.7 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0081) DUF4200 PF13863.1 EIW82305.1 - 0.93 9.4 6.6 0.22 11.4 1.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Iso_dh PF00180.15 EIW82306.1 - 2.1e-123 411.7 0.0 2.6e-123 411.4 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Toxin_67 PF15545.1 EIW82307.1 - 0.044 13.6 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative toxin 67 P21-Arc PF04062.9 EIW82308.1 - 1.8e-77 259.0 0.0 2e-77 258.9 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Sld5 PF05916.6 EIW82310.1 - 6.9e-17 61.6 0.2 9.9e-17 61.2 0.1 1.2 1 0 0 1 1 1 1 GINS complex protein DUF790 PF05626.6 EIW82310.1 - 0.079 11.4 0.0 0.099 11.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF790) DUF3635 PF12330.3 EIW82311.1 - 4.2e-19 68.4 0.0 7.4e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3635) Methyltransf_23 PF13489.1 EIW82312.1 - 2.9e-12 46.6 0.0 3.6e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW82312.1 - 7.6e-08 32.7 0.0 1.2e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW82312.1 - 1.3e-05 25.6 0.0 3.3e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW82312.1 - 2.1e-05 24.1 0.0 4.2e-05 23.1 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW82312.1 - 2.1e-05 25.0 0.0 3.8e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EIW82312.1 - 0.056 12.4 0.0 0.088 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DUF1212 PF06738.7 EIW82315.1 - 2.8e-32 111.7 1.9 2.8e-32 111.7 1.3 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EIW82315.1 - 2.9e-14 53.1 25.4 3.3e-14 52.9 6.4 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) Acetyltransf_1 PF00583.19 EIW82316.1 - 8.8e-08 32.0 0.1 2e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIW82316.1 - 2e-05 24.6 0.0 8.2e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIW82316.1 - 0.00027 21.1 0.0 0.0027 17.8 0.0 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIW82316.1 - 0.00032 20.3 0.0 0.00055 19.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EIW82316.1 - 0.028 14.3 0.0 0.056 13.3 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Lipase_GDSL PF00657.17 EIW82317.1 - 4.3e-06 26.7 0.0 0.00041 20.2 0.0 2.3 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase tRNA-synt_2d PF01409.15 EIW82318.1 - 2.9e-85 285.3 0.0 1.6e-55 188.0 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EIW82318.1 - 5.2e-07 28.7 0.6 0.0023 16.7 0.0 3.3 4 0 0 4 4 4 2 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EIW82318.1 - 0.00029 20.4 0.0 0.00064 19.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Pex2_Pex12 PF04757.9 EIW82319.1 - 3.4e-33 114.9 5.8 4.8e-33 114.4 4.0 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EIW82319.1 - 0.00053 19.9 1.2 0.00053 19.9 0.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW82319.1 - 0.0015 18.2 6.2 0.0016 18.1 2.4 2.2 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIW82319.1 - 0.0037 16.8 4.3 0.024 14.2 3.0 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIW82319.1 - 0.0042 16.9 3.1 0.024 14.5 2.4 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EIW82319.1 - 0.0082 15.8 0.3 0.022 14.4 0.0 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.1 EIW82319.1 - 0.021 14.6 8.4 0.17 11.7 3.8 2.8 2 1 1 3 3 3 0 Ring finger domain zf-rbx1 PF12678.2 EIW82319.1 - 0.094 12.8 1.9 0.36 10.9 1.4 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger BRCT PF00533.21 EIW82320.1 - 8.5e-06 25.8 0.0 1.4e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Mur_ligase_M PF08245.7 EIW82321.1 - 2.6e-06 27.6 0.0 8.7e-05 22.6 0.0 2.4 1 1 0 1 1 1 1 Mur ligase middle domain MS_channel PF00924.13 EIW82322.1 - 1.2e-15 57.4 2.2 2.5e-15 56.3 1.5 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EIW82322.1 - 5.4e-06 25.3 0.0 1.3e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.1 EIW82322.1 - 9.7e-05 21.5 0.1 0.00039 19.6 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EIW82322.1 - 0.00016 21.2 0.0 0.00058 19.5 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 EIW82322.1 - 0.0027 17.7 0.0 0.0085 16.2 0.0 1.8 1 1 0 1 1 1 1 EF-hand domain pair DUF1129 PF06570.6 EIW82322.1 - 0.031 13.6 0.1 0.11 11.7 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) EF-hand_8 PF13833.1 EIW82322.1 - 0.075 12.6 0.1 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain pair PBP1_TM PF14812.1 EIW82322.1 - 0.096 12.9 0.0 0.096 12.9 0.0 2.5 2 1 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal IBN_N PF03810.14 EIW82323.1 - 6.5e-07 29.1 0.0 0.00027 20.8 0.0 3.6 3 0 0 3 3 3 2 Importin-beta N-terminal domain Xpo1 PF08389.7 EIW82323.1 - 0.0032 17.4 0.9 0.021 14.7 0.0 2.9 3 0 0 3 3 3 1 Exportin 1-like protein Vps52 PF04129.7 EIW82324.1 - 8.7e-58 196.0 0.0 4.1e-32 111.3 0.0 3.0 3 0 0 3 3 3 3 Vps52 / Sac2 family Sec3_C PF09763.4 EIW82324.1 - 0.00052 18.3 0.0 0.038 12.1 0.0 2.3 1 1 0 1 1 1 1 Exocyst complex component Sec3 Cep57_MT_bd PF06657.8 EIW82324.1 - 0.037 13.9 0.4 0.13 12.1 0.3 1.9 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 Aldose_epim PF01263.15 EIW82326.1 - 4e-52 177.2 0.2 5.1e-52 176.8 0.2 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase JAB PF01398.16 EIW82328.1 - 1.3e-35 121.5 0.8 2.4e-35 120.7 0.6 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EIW82328.1 - 2.8e-27 95.0 1.9 6.6e-27 93.8 1.3 1.7 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EIW82328.1 - 6.6e-08 32.0 0.0 1.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 EIW82328.1 - 0.019 14.4 1.0 0.064 12.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0172) Ribosomal_S18 PF01084.15 EIW82329.1 - 7.1e-16 57.8 0.1 1.2e-15 57.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S18 Pkinase PF00069.20 EIW82330.1 - 1.7e-63 214.1 0.0 8e-41 139.9 0.0 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW82330.1 - 1.7e-27 96.1 0.0 8.7e-23 80.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EIW82330.1 - 4e-13 49.3 0.2 7e-13 48.5 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EIW82330.1 - 6.5e-07 28.5 0.1 0.00019 20.5 0.0 2.4 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 EIW82330.1 - 0.0033 17.1 2.2 0.0046 16.7 0.1 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIW82330.1 - 0.0095 15.2 0.6 0.06 12.6 0.0 2.2 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 EIW82330.1 - 0.014 14.4 0.0 0.028 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EIW82330.1 - 0.037 12.8 0.0 0.06 12.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 THOC7 PF05615.8 EIW82332.1 - 3.3e-23 82.5 4.9 3.8e-23 82.2 3.0 1.4 1 1 0 1 1 1 1 Tho complex subunit 7 DUF842 PF05811.8 EIW82332.1 - 0.0022 17.4 0.7 0.0045 16.4 0.3 1.6 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) PAM2 PF07145.10 EIW82332.1 - 0.0044 16.4 0.4 0.01 15.3 0.2 1.5 1 0 0 1 1 1 1 Ataxin-2 C-terminal region AAA_13 PF13166.1 EIW82332.1 - 0.15 10.5 2.7 0.2 10.0 1.8 1.1 1 0 0 1 1 1 0 AAA domain DUF342 PF03961.8 EIW82332.1 - 0.57 8.5 5.6 0.8 8.0 3.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF4337 PF14235.1 EIW82332.1 - 4.9 6.9 8.2 2.3 8.0 3.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Lactamase_B_2 PF12706.2 EIW82333.1 - 3.3e-22 78.9 0.0 5e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIW82333.1 - 4.5e-10 39.4 0.1 6.8e-10 38.9 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_4 PF13691.1 EIW82333.1 - 1.5e-06 27.5 0.0 3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 tRNase Z endonuclease zf-RING_5 PF14634.1 EIW82334.1 - 5.3e-06 26.0 9.8 8.5e-06 25.3 6.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EIW82334.1 - 5.8e-06 26.0 9.6 1e-05 25.2 6.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EIW82334.1 - 1.8e-05 24.2 8.8 3e-05 23.5 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW82334.1 - 0.00058 19.8 10.3 0.00099 19.0 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIW82334.1 - 0.009 15.8 10.1 0.016 15.0 7.0 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EIW82334.1 - 0.0097 15.4 10.5 0.02 14.4 7.3 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EIW82334.1 - 0.017 14.8 5.4 0.041 13.5 3.7 1.7 1 0 0 1 1 1 0 RING-type zinc-finger TBPIP PF07106.8 EIW82334.1 - 0.039 13.5 4.7 0.064 12.8 3.3 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) TMF_DNA_bd PF12329.3 EIW82334.1 - 0.063 13.0 8.4 1.1 9.1 4.2 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SWI-SNF_Ssr4 PF08549.5 EIW82334.1 - 0.17 10.1 5.2 0.48 8.6 1.0 2.1 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) DUF972 PF06156.8 EIW82334.1 - 0.87 9.9 6.2 11 6.4 0.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Prok-RING_4 PF14447.1 EIW82334.1 - 0.95 9.0 8.2 16 5.1 5.7 2.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 IncA PF04156.9 EIW82334.1 - 1.5 8.3 7.2 2.8 7.4 5.0 1.4 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EIW82334.1 - 1.7 8.2 9.4 9 5.8 0.0 2.4 2 0 0 2 2 2 0 Septum formation initiator Vps39_2 PF10367.4 EIW82334.1 - 1.8 8.7 7.3 4.3 7.5 5.1 1.7 1 1 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 DUF4407 PF14362.1 EIW82334.1 - 2.6 6.9 6.9 4.7 6.0 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CASP_C PF08172.7 EIW82334.1 - 5.5 5.9 11.1 7.2 5.5 2.6 2.3 2 0 0 2 2 2 0 CASP C terminal RhoGEF PF00621.15 EIW82335.1 - 4.7e-37 127.6 0.1 2.2e-36 125.4 0.1 1.9 2 0 0 2 2 2 1 RhoGEF domain DUF972 PF06156.8 EIW82335.1 - 2.4 8.5 8.0 8.8 6.7 0.6 3.1 1 1 1 2 2 2 0 Protein of unknown function (DUF972) RhoGEF PF00621.15 EIW82336.1 - 3.2e-20 72.7 0.0 3e-18 66.3 0.0 2.9 3 1 0 3 3 3 1 RhoGEF domain PH PF00169.24 EIW82336.1 - 0.017 15.3 0.0 0.049 13.8 0.0 1.8 1 0 0 1 1 1 0 PH domain PH_6 PF15406.1 EIW82336.1 - 0.12 12.4 0.0 0.42 10.6 0.0 2.0 1 0 0 1 1 1 0 Pleckstrin homology domain LRR_6 PF13516.1 EIW82337.1 - 3.3e-11 42.0 0.1 5.9 7.2 0.0 9.4 10 0 0 10 10 10 2 Leucine Rich repeat LRR_4 PF12799.2 EIW82337.1 - 3.6e-11 42.4 0.0 1.5 8.5 0.1 6.9 5 3 2 7 7 7 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIW82337.1 - 6e-11 40.8 5.4 4.4 7.7 0.3 8.4 7 1 0 7 7 7 3 Leucine Rich Repeat LRR_7 PF13504.1 EIW82337.1 - 6e-08 31.6 11.2 24 5.7 0.0 8.5 8 0 0 8 8 8 2 Leucine rich repeat Myb_DNA-binding PF00249.26 EIW82339.1 - 1.4e-19 69.8 8.0 3.6e-10 39.7 0.0 4.7 5 0 0 5 5 5 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIW82339.1 - 2e-18 66.2 2.4 1.4e-12 47.4 0.0 4.2 3 1 2 5 5 5 2 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EIW82339.1 - 0.00051 20.1 1.3 0.00051 20.1 0.9 3.6 3 2 0 3 3 3 1 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 EIW82339.1 - 0.12 12.2 2.4 2 8.3 1.7 2.5 1 1 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF2052 PF09747.4 EIW82340.1 - 2e-06 27.8 13.1 5.5e-06 26.4 9.1 1.7 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) PAF-AH_p_II PF03403.8 EIW82341.1 - 2.1e-39 134.9 0.0 2.7e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EIW82341.1 - 1.1e-09 38.1 0.0 3e-09 36.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW82341.1 - 4.9e-05 23.3 0.4 0.00011 22.1 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EIW82341.1 - 0.00028 19.8 0.0 0.0034 16.3 0.0 2.1 1 1 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 EIW82341.1 - 0.13 12.1 0.0 0.47 10.3 0.0 1.9 2 0 0 2 2 2 0 Putative lysophospholipase Myb_DNA-bind_6 PF13921.1 EIW82342.1 - 5.4e-06 26.4 0.4 1.4e-05 25.0 0.3 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIW82342.1 - 0.00036 20.5 1.4 0.00067 19.6 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF202 PF02656.10 EIW82343.1 - 1.2e-13 51.0 1.5 1.2e-13 51.0 1.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) TctB PF07331.6 EIW82343.1 - 0.039 13.6 2.8 0.39 10.3 0.1 2.1 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctB family zf-U1 PF06220.7 EIW82344.1 - 1.3e-20 72.6 4.1 1.8e-20 72.1 2.8 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EIW82344.1 - 0.014 15.4 2.3 0.024 14.7 1.6 1.4 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding LSM PF01423.17 EIW82345.1 - 6.2e-19 67.3 0.2 7.6e-19 67.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF4050 PF13259.1 EIW82346.1 - 0.0006 19.7 0.3 0.0012 18.7 0.2 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4050) F-box-like PF12937.2 EIW82347.1 - 1.6e-11 43.7 3.3 1.6e-11 43.7 2.3 2.9 3 0 0 3 3 3 1 F-box-like LRR_4 PF12799.2 EIW82347.1 - 1.5e-10 40.4 2.0 0.26 10.9 0.0 5.3 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW82347.1 - 0.0037 16.9 10.1 13 5.5 0.1 5.9 5 1 2 7 7 7 2 Leucine rich repeat Acetyltransf_1 PF00583.19 EIW82348.1 - 1.1e-14 54.1 0.1 1.5e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EIW82348.1 - 3.7e-06 27.0 0.0 4.6e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIW82348.1 - 1.6e-05 24.5 0.3 2.9e-05 23.7 0.1 1.5 1 1 1 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.1 EIW82348.1 - 0.00017 21.6 0.0 0.00026 21.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIW82348.1 - 0.00078 19.3 0.1 0.001 18.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIW82348.1 - 0.024 14.8 0.0 0.16 12.1 0.0 1.9 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain tRNA-synt_1c PF00749.16 EIW82349.1 - 5.6e-104 347.1 0.0 8.9e-104 346.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EIW82349.1 - 7.1e-32 110.4 0.0 1.4e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.10 EIW82349.1 - 1.1e-29 103.0 0.0 1.8e-29 102.3 0.0 1.3 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.10 EIW82349.1 - 1.9e-10 41.3 3.1 5.2e-10 39.8 2.1 1.8 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 CPSF100_C PF13299.1 EIW82350.1 - 3.6e-27 95.5 0.0 3.6e-27 95.5 0.0 3.9 4 1 0 4 4 4 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EIW82350.1 - 1e-21 77.1 0.0 8.1e-21 74.2 0.0 2.4 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_2 PF12706.2 EIW82350.1 - 5.1e-07 29.4 0.0 1.1e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Abhydrolase_3 PF07859.8 EIW82351.1 - 1.4e-37 129.3 0.0 9.1e-30 103.8 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EIW82351.1 - 4.1e-11 42.1 0.0 1.6e-10 40.2 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EIW82351.1 - 0.0042 16.8 0.0 0.018 14.7 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Tubulin PF00091.20 EIW82352.1 - 1.8e-67 227.3 0.0 2.4e-67 226.9 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIW82352.1 - 4.4e-47 159.2 0.0 6.7e-47 158.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EIW82352.1 - 0.00029 20.3 0.0 0.00056 19.4 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Lipase_3 PF01764.20 EIW82352.1 - 0.0081 15.7 0.1 2 8.0 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) Tubulin PF00091.20 EIW82353.1 - 3.1e-67 226.5 0.0 4.1e-67 226.1 0.0 1.1 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIW82353.1 - 6.9e-45 152.1 0.0 1e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EIW82353.1 - 0.0013 18.2 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Sec15 PF04091.7 EIW82354.1 - 2.9e-69 233.7 0.0 2.9e-69 233.7 0.0 2.2 3 0 0 3 3 3 1 Exocyst complex subunit Sec15-like COG5 PF10392.4 EIW82354.1 - 6.7e-08 32.5 2.0 6.7e-08 32.5 1.4 2.6 2 0 0 2 2 2 1 Golgi transport complex subunit 5 Vps51 PF08700.6 EIW82354.1 - 8.7e-06 25.4 2.6 1.8e-05 24.4 0.3 2.8 2 0 0 2 2 2 1 Vps51/Vps67 Sec8_exocyst PF04048.9 EIW82354.1 - 1.7e-05 24.4 1.4 5.8e-05 22.7 1.0 1.9 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Sec5 PF15469.1 EIW82354.1 - 8.8e-05 22.3 0.2 0.00036 20.3 0.2 2.1 1 0 0 1 1 1 1 Exocyst complex component Sec5 COG2 PF06148.6 EIW82354.1 - 0.0054 16.6 2.7 0.0054 16.6 1.9 2.8 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 HsbA PF12296.3 EIW82354.1 - 0.053 13.3 6.1 0.13 12.1 0.3 3.8 4 0 0 4 4 4 0 Hydrophobic surface binding protein A Ku_PK_bind PF08785.6 EIW82354.1 - 0.06 13.2 3.4 1.7 8.5 0.2 3.8 3 1 0 3 3 3 0 Ku C terminal domain like DSPc PF00782.15 EIW82355.1 - 1.7e-29 102.1 0.1 2e-29 101.8 0.1 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIW82355.1 - 6.4e-05 22.4 0.7 0.0001 21.7 0.4 1.3 1 1 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 EIW82355.1 - 0.018 14.5 0.2 0.028 13.8 0.1 1.4 1 1 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 EIW82355.1 - 0.048 13.7 0.0 0.065 13.2 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate Neisseria_TspB PF05616.8 EIW82356.1 - 0.11 10.8 5.6 0.16 10.3 3.9 1.3 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein SIP1 PF04938.7 EIW82357.1 - 6e-23 81.4 2.7 2.4e-13 49.9 0.9 2.2 2 0 0 2 2 2 2 Survival motor neuron (SMN) interacting protein 1 (SIP1) QRPTase_C PF01729.14 EIW82358.1 - 2.7e-48 163.6 0.0 3.3e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EIW82358.1 - 2.4e-20 72.1 0.0 8.4e-20 70.3 0.0 2.0 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Amidohydro_2 PF04909.9 EIW82359.1 - 2.5e-27 96.1 5.6 7.9e-27 94.4 3.9 1.8 1 1 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 EIW82359.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 TatD related DNase NIF PF03031.13 EIW82362.1 - 8.7e-44 148.9 0.0 1e-43 148.7 0.0 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Snf7 PF03357.16 EIW82363.1 - 5.5e-34 117.0 15.4 5.5e-34 117.0 10.7 2.0 1 1 1 2 2 2 1 Snf7 Birna_RdRp PF04197.7 EIW82363.1 - 0.13 10.2 4.5 0.15 10.0 3.1 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) LEA_1 PF03760.10 EIW82363.1 - 1.4 9.1 11.1 1.5 9.0 0.2 2.7 2 0 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 PLRV_ORF5 PF01690.12 EIW82363.1 - 1.4 7.9 4.2 1.7 7.6 2.9 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein DUF3619 PF12279.3 EIW82363.1 - 1.5 8.8 6.6 3.8 7.5 3.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3619) Atg14 PF10186.4 EIW82363.1 - 5.1 5.9 12.3 7.5 5.3 8.0 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TRAM_LAG1_CLN8 PF03798.11 EIW82364.1 - 8.6e-39 133.1 24.4 1.3e-38 132.5 16.9 1.3 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 EIW82364.1 - 6.8e-08 31.8 0.1 6.8e-08 31.8 0.0 2.3 2 0 0 2 2 2 1 TRAM1-like protein RRM_5 PF13893.1 EIW82365.1 - 2.6e-11 43.1 0.0 4e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIW82365.1 - 4.3e-07 29.4 0.0 1.2e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW82365.1 - 4.3e-05 23.4 0.0 9.4e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DJ-1_PfpI PF01965.19 EIW82366.1 - 3.1e-28 98.0 0.1 5.1e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EIW82366.1 - 1.4e-10 40.5 0.1 2.7e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DUF4066 PF13278.1 EIW82366.1 - 0.072 12.3 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 Putative amidotransferase BRCT PF00533.21 EIW82366.1 - 0.076 13.1 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Mob1_phocein PF03637.12 EIW82367.1 - 1.7e-74 249.2 0.0 2e-74 249.0 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family DEAD PF00270.24 EIW82369.1 - 1.7e-43 148.0 0.0 2.6e-43 147.4 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW82369.1 - 6e-23 80.5 0.0 1.2e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW82369.1 - 0.031 14.0 0.0 0.098 12.4 0.0 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Sua5_yciO_yrdC PF01300.13 EIW82370.1 - 2.9e-53 179.7 0.0 9.9e-53 178.0 0.0 1.8 2 0 0 2 2 2 1 Telomere recombination SUA5 PF03481.8 EIW82370.1 - 1.4e-24 86.5 0.0 2.5e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding Complex1_LYR_2 PF13233.1 EIW82370.1 - 6.3e-08 33.0 3.6 1.2e-07 32.1 2.5 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Ndr PF03096.9 EIW82370.1 - 0.28 9.6 0.4 0.51 8.7 0.3 1.3 1 0 0 1 1 1 0 Ndr family DEAD PF00270.24 EIW82371.1 - 6.8e-16 58.2 0.0 1.9e-15 56.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW82371.1 - 1.2e-07 31.4 0.0 2.8e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ACPS PF01648.15 EIW82372.1 - 8.9e-24 83.5 0.0 1e-23 83.3 0.0 1.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Acyltransferase PF01553.16 EIW82372.1 - 0.018 14.4 0.0 0.052 12.9 0.0 1.8 2 1 0 2 2 2 0 Acyltransferase GCV_T PF01571.16 EIW82373.1 - 1.3e-16 60.6 0.0 8.7e-16 57.9 0.0 2.0 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EIW82373.1 - 0.0005 20.0 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pet191_N PF10203.4 EIW82374.1 - 5.4e-24 84.0 5.5 6.2e-24 83.8 3.8 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 EIW82374.1 - 2.3 8.2 8.0 5.8 6.9 0.2 2.5 3 0 0 3 3 3 0 CHCH domain Cmc1 PF08583.5 EIW82374.1 - 5.7 6.7 6.7 3.3e+02 1.1 4.7 2.6 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like GST_C PF00043.20 EIW82375.1 - 2.3e-12 46.7 0.0 5e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIW82375.1 - 5.6e-12 45.7 0.0 1e-11 44.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW82375.1 - 1.7e-09 37.7 0.0 3.7e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW82375.1 - 3.3e-09 36.6 0.0 7e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW82375.1 - 1.5e-07 31.1 0.0 3.6e-07 29.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW82375.1 - 0.002 18.5 0.0 0.0037 17.7 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1640 PF07798.6 EIW82376.1 - 2.1e-13 50.6 0.3 2.5e-13 50.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF605 PF04652.11 EIW82376.1 - 6.8 5.9 17.4 0.075 12.4 6.0 1.9 2 0 0 2 2 2 0 Vta1 like ATP_bind_1 PF03029.12 EIW82377.1 - 2.6e-72 243.1 0.0 3.3e-72 242.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.18 EIW82377.1 - 2.5e-05 23.7 0.0 4.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 EIW82377.1 - 5.8e-05 23.8 0.0 0.00011 23.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 EIW82377.1 - 0.00065 18.5 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 ArgK protein ArsA_ATPase PF02374.10 EIW82377.1 - 0.0011 18.0 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_16 PF13191.1 EIW82377.1 - 0.0052 16.7 0.0 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EIW82377.1 - 0.0069 15.8 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EIW82377.1 - 0.017 15.2 0.0 0.03 14.4 0.0 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIW82377.1 - 0.018 14.1 0.0 0.06 12.4 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 EIW82377.1 - 0.02 14.6 0.1 0.086 12.6 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 EIW82377.1 - 0.02 14.7 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EIW82377.1 - 0.021 14.4 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EIW82377.1 - 0.028 14.1 0.0 0.055 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SE PF00437.15 EIW82377.1 - 0.032 13.1 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 EIW82377.1 - 0.035 13.2 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 KaiC MobB PF03205.9 EIW82377.1 - 0.043 13.5 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EIW82377.1 - 0.044 13.2 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 EIW82377.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EIW82377.1 - 0.082 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RNA_helicase PF00910.17 EIW82377.1 - 0.084 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 EIW82377.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain MipZ PF09140.6 EIW82377.1 - 0.1 11.6 0.0 1.2 8.1 0.0 2.2 1 1 0 1 1 1 0 ATPase MipZ AAA_18 PF13238.1 EIW82377.1 - 0.1 12.8 0.0 0.21 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EIW82377.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EIW82377.1 - 0.19 11.4 0.1 0.42 10.3 0.0 1.6 2 0 0 2 2 1 0 NTPase Chromo PF00385.19 EIW82379.1 - 5.1e-12 45.2 1.1 5.1e-12 45.2 0.7 2.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain MFS_1 PF07690.11 EIW82380.1 - 9e-25 87.1 18.4 1.2e-24 86.6 12.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Phage_holin_5 PF06946.6 EIW82380.1 - 0.13 12.4 1.0 0.33 11.1 0.1 2.2 2 0 0 2 2 2 0 Phage holin Thiolase_N PF00108.18 EIW82381.1 - 1.4e-88 296.2 1.8 2e-88 295.7 1.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EIW82381.1 - 1.5e-38 131.0 1.4 1.5e-38 131.0 1.0 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EIW82381.1 - 1.9e-05 24.2 2.5 0.00082 18.9 1.3 2.7 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EIW82381.1 - 0.034 13.7 2.7 0.093 12.3 0.0 2.7 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Autophagy_act_C PF03987.10 EIW82382.1 - 4e-14 52.5 0.2 6.6e-14 51.8 0.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Ribosomal_S3Ae PF01015.13 EIW82383.1 - 7.5e-87 289.6 6.2 8.9e-87 289.4 4.3 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Ph1570 PF09638.5 EIW82383.1 - 0.013 15.3 0.2 3.7 7.3 0.1 2.4 2 1 0 2 2 2 0 Ph1570 protein mRNA_cap_C PF03919.10 EIW82383.1 - 0.033 14.5 0.2 0.072 13.4 0.1 1.6 1 0 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Abhydro_lipase PF04083.11 EIW82383.1 - 0.038 13.3 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Pribosyltran PF00156.22 EIW82384.1 - 5.3e-17 61.6 0.1 7.1e-17 61.3 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EIW82384.1 - 0.0076 15.4 0.0 0.011 14.9 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Glyco_hydro_47 PF01532.15 EIW82385.1 - 6.1e-128 427.2 0.0 7.7e-128 426.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.17 EIW82385.1 - 4e-09 36.0 0.0 8.1e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 PA domain Auto_anti-p27 PF06677.7 EIW82386.1 - 1e-11 44.3 3.7 9.3e-05 22.1 1.0 2.8 2 1 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Ocular_alb PF02101.10 EIW82386.1 - 0.032 12.8 0.3 0.05 12.2 0.2 1.2 1 0 0 1 1 1 0 Ocular albinism type 1 protein Ribonuclease_3 PF00636.21 EIW82390.1 - 5.9e-44 149.1 0.0 1.1e-20 74.1 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EIW82390.1 - 2.2e-27 95.5 0.1 1.1e-10 41.5 0.0 4.4 4 0 0 4 4 4 4 Ribonuclease-III-like Dicer_dimer PF03368.9 EIW82390.1 - 1e-05 25.1 0.1 3e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain PAZ PF02170.17 EIW82390.1 - 6.6e-05 22.2 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 PAZ domain dsrm PF00035.20 EIW82390.1 - 0.0024 18.3 0.0 1.8 9.2 0.0 2.7 2 0 0 2 2 2 2 Double-stranded RNA binding motif COX7C PF02935.11 EIW82391.1 - 2.4e-09 36.8 0.7 3.1e-09 36.4 0.5 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Aldedh PF00171.17 EIW82392.1 - 4.7e-177 588.9 0.0 5.3e-177 588.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIW82392.1 - 0.09 11.4 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) AhpC-TSA PF00578.16 EIW82393.1 - 9.5e-34 115.7 0.0 1.2e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIW82393.1 - 1.5e-13 50.5 0.0 2e-13 50.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EIW82393.1 - 2.7e-09 36.4 0.0 5.1e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Ssu72 PF04722.8 EIW82394.1 - 2.6e-82 274.8 0.0 3e-82 274.6 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein F-box-like PF12937.2 EIW82395.1 - 6.3e-05 22.6 2.1 9.2e-05 22.0 0.1 2.4 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EIW82395.1 - 0.011 15.2 0.5 0.77 9.4 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EIW82395.1 - 0.031 14.3 3.3 1.9 8.8 0.0 4.2 3 1 0 3 3 3 0 Leucine Rich repeat IMD PF08397.6 EIW82395.1 - 0.086 12.1 0.1 0.14 11.4 0.1 1.2 1 0 0 1 1 1 0 IRSp53/MIM homology domain Syntaxin-18_N PF10496.4 EIW82396.1 - 4.2e-10 39.3 0.1 1.6e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.14 EIW82396.1 - 0.0064 16.1 7.0 0.012 15.2 2.3 2.6 2 0 0 2 2 2 1 SNARE domain DUF4094 PF13334.1 EIW82396.1 - 0.012 16.0 3.0 0.016 15.5 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) SNARE_assoc PF09335.6 EIW82397.1 - 3.9e-12 46.4 17.5 1.5e-11 44.5 7.7 3.2 2 1 1 3 3 3 1 SNARE associated Golgi protein MarC PF01914.12 EIW82397.1 - 0.041 12.9 3.1 0.051 12.6 0.2 2.4 2 1 0 2 2 2 0 MarC family integral membrane protein DUF1206 PF06724.6 EIW82397.1 - 0.066 12.9 8.2 0.46 10.2 2.5 3.7 3 1 0 3 3 3 0 Domain of Unknown Function (DUF1206) Orthoreo_P10 PF07204.6 EIW82397.1 - 0.11 12.2 0.2 0.62 9.8 0.0 2.2 2 0 0 2 2 2 0 Orthoreovirus membrane fusion protein p10 Neur_chan_memb PF02932.11 EIW82397.1 - 0.12 12.2 1.2 0.41 10.4 0.4 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF2393 PF09624.5 EIW82397.1 - 0.33 10.4 1.9 0.7 9.4 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2393) DUF2636 PF11120.3 EIW82397.1 - 0.78 9.2 0.0 0.78 9.2 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2636) Fungal_trans PF04082.13 EIW82398.1 - 1.2e-20 73.5 0.9 4.4e-20 71.6 0.2 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW82398.1 - 2e-05 24.4 11.1 3.5e-05 23.6 7.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DPBB_1 PF03330.13 EIW82399.1 - 4.6e-08 32.9 0.0 7.4e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIW82399.1 - 0.045 13.4 1.3 0.081 12.5 0.4 1.7 1 1 1 2 2 2 0 Barwin family WD40 PF00400.27 EIW82400.1 - 7.7e-74 241.1 13.0 5.9e-09 35.4 0.0 11.6 11 0 0 11 11 11 11 WD domain, G-beta repeat Utp12 PF04003.7 EIW82400.1 - 2.6e-17 62.7 2.9 4.2e-17 62.0 2.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Nucleoporin_N PF08801.6 EIW82400.1 - 7.2e-07 28.2 4.5 4.3 5.9 0.0 6.1 2 2 1 5 5 5 4 Nup133 N terminal like Nup160 PF11715.3 EIW82400.1 - 0.00018 19.8 14.9 0.017 13.2 1.3 5.3 4 3 0 4 4 4 4 Nucleoporin Nup120/160 DUF3312 PF11768.3 EIW82400.1 - 0.018 13.3 0.1 0.45 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Peptidase_M18 PF02127.10 EIW82401.1 - 1.7e-154 514.4 0.0 1.9e-154 514.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Fib_alpha PF08702.5 EIW82402.1 - 0.019 15.0 0.3 0.026 14.6 0.2 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Bud13 PF09736.4 EIW82402.1 - 0.073 13.3 1.7 0.08 13.2 1.2 1.0 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Hpr_kinase_N PF02603.11 EIW82403.1 - 0.05 13.2 0.0 0.082 12.6 0.0 1.3 2 0 0 2 2 2 0 HPr Serine kinase N terminus Ribonuc_red_sm PF00268.16 EIW82404.1 - 6.6e-121 402.6 1.8 8.2e-121 402.3 1.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain VMA21 PF09446.5 EIW82405.1 - 6.3e-08 32.4 11.4 1.1e-07 31.6 7.9 1.4 1 1 0 1 1 1 1 VMA21-like domain MFS_1 PF07690.11 EIW82405.1 - 0.0032 16.2 0.4 0.0035 16.1 0.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TMC PF07810.8 EIW82405.1 - 0.036 14.4 0.4 0.045 14.1 0.3 1.2 1 0 0 1 1 1 0 TMC domain Alg6_Alg8 PF03155.10 EIW82406.1 - 1.3e-126 423.2 34.0 1.6e-126 422.9 23.6 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family TGS PF02824.16 EIW82407.1 - 3.1e-25 87.7 0.1 5.3e-25 87.0 0.1 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EIW82407.1 - 1.3e-09 38.0 0.2 6.5e-09 35.7 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIW82407.1 - 5.1e-06 25.8 0.0 9.3e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 EIW82407.1 - 0.0082 14.9 0.1 0.015 14.0 0.1 1.4 1 0 0 1 1 1 1 ArgK protein DUF211 PF02680.9 EIW82407.1 - 0.095 12.5 0.5 0.33 10.7 0.2 2.1 2 0 0 2 2 2 0 Uncharacterized ArCR, COG1888 BAP PF06639.6 EIW82408.1 - 0.13 12.0 0.1 0.41 10.3 0.1 1.8 1 0 0 1 1 1 0 Basal layer antifungal peptide (BAP) V-SNARE PF05008.10 EIW82409.1 - 2.5e-21 75.6 7.3 7.2e-21 74.1 1.5 2.4 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EIW82409.1 - 4.9e-19 68.1 4.8 4.9e-19 68.1 3.3 2.3 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EIW82409.1 - 2.6e-05 23.8 1.7 4.6e-05 23.0 0.1 2.0 2 0 0 2 2 2 1 Sec20 Fusion_gly PF00523.13 EIW82409.1 - 0.0034 15.5 0.4 0.0052 14.9 0.3 1.3 1 0 0 1 1 1 1 Fusion glycoprotein F0 Phospholamban PF04272.9 EIW82409.1 - 0.0082 15.5 0.4 0.025 14.0 0.3 1.8 1 0 0 1 1 1 1 Phospholamban DUF3770 PF12603.3 EIW82409.1 - 0.0093 15.1 1.4 2.2 7.3 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3770) Laminin_I PF06008.9 EIW82409.1 - 0.028 13.7 8.0 0.61 9.3 0.5 2.2 2 0 0 2 2 2 0 Laminin Domain I ApoLp-III PF07464.6 EIW82409.1 - 0.035 14.1 6.2 0.88 9.5 0.4 2.2 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) YqjK PF13997.1 EIW82409.1 - 0.059 13.5 0.9 0.059 13.5 0.6 1.9 2 0 0 2 2 1 0 YqjK-like protein Nup54 PF13874.1 EIW82409.1 - 0.064 12.9 2.9 1.8 8.2 0.2 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF1366 PF07104.6 EIW82409.1 - 0.093 12.3 0.5 0.18 11.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) TBPIP PF07106.8 EIW82409.1 - 0.099 12.1 4.5 3.5 7.1 0.2 2.1 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prominin PF05478.6 EIW82409.1 - 0.12 9.8 2.5 0.24 8.8 1.7 1.5 1 1 0 1 1 1 0 Prominin OppC_N PF12911.2 EIW82409.1 - 0.2 11.0 1.6 0.37 10.2 1.1 1.3 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C MYCBPAP PF14646.1 EIW82409.1 - 0.25 10.0 7.4 0.24 10.0 0.3 2.0 2 0 0 2 2 2 0 MYCBP-associated protein family FliJ PF02050.11 EIW82409.1 - 0.53 10.3 9.6 2 8.4 0.9 2.5 2 0 0 2 2 2 0 Flagellar FliJ protein Flagellin_N PF00669.15 EIW82409.1 - 0.59 9.9 7.9 0.4 10.4 0.8 3.1 1 1 3 4 4 4 0 Bacterial flagellin N-terminal helical region DUF3619 PF12279.3 EIW82409.1 - 0.98 9.5 4.4 1.8 8.6 0.4 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF3619) Sec8_exocyst PF04048.9 EIW82409.1 - 1.3 8.6 4.7 0.55 9.8 0.1 2.3 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain Tmemb_cc2 PF10267.4 EIW82409.1 - 6.7 5.1 12.6 0.034 12.7 1.1 2.3 2 1 1 3 3 3 0 Predicted transmembrane and coiled-coil 2 protein EF-hand_1 PF00036.27 EIW82410.1 - 5.1e-25 84.8 12.7 8.6e-08 30.9 0.2 5.2 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.1 EIW82410.1 - 9.7e-24 83.2 7.2 4.4e-14 52.3 0.5 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EIW82410.1 - 6.6e-20 69.1 6.9 3.6e-06 26.4 0.1 5.2 4 1 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.1 EIW82410.1 - 3.2e-12 45.1 13.3 0.00041 19.5 0.7 4.7 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 EIW82410.1 - 5.8e-12 45.0 9.7 1.3e-05 24.7 0.6 3.7 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 EIW82410.1 - 1e-07 31.6 6.7 0.014 15.1 0.1 4.0 2 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EIW82410.1 - 0.00025 21.0 2.7 0.083 12.9 0.2 3.4 2 2 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EIW82410.1 - 0.0032 17.3 2.7 1.2 9.0 0.0 3.4 2 1 1 3 3 3 2 EF-hand domain EF-hand_10 PF14788.1 EIW82410.1 - 0.0058 16.2 1.5 32 4.2 0.0 4.2 4 0 0 4 4 4 0 EF hand S10_plectin PF03501.10 EIW82410.1 - 0.038 13.8 0.0 0.062 13.1 0.0 1.4 1 0 0 1 1 1 0 Plectin/S10 domain EF-hand_2 PF09068.6 EIW82410.1 - 0.072 13.1 0.0 2 8.5 0.0 2.7 3 0 0 3 3 3 0 EF hand DAG_kinase_N PF14513.1 EIW82410.1 - 0.33 11.1 2.0 0.44 10.7 1.4 1.5 1 1 0 1 1 1 0 Diacylglycerol kinase N-terminus Adeno_PIX PF03955.9 EIW82411.1 - 2.8 8.4 6.3 0.31 11.5 0.4 2.3 2 1 0 2 2 2 0 Adenovirus hexon-associated protein (IX) WD40 PF00400.27 EIW82412.1 - 0.00097 18.9 1.2 0.047 13.6 0.1 3.3 3 0 0 3 3 3 1 WD domain, G-beta repeat DUF839 PF05787.8 EIW82412.1 - 0.021 13.7 0.0 0.031 13.2 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF839) DUF1513 PF07433.6 EIW82412.1 - 0.024 13.5 0.0 0.084 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Peptidase_S24 PF00717.18 EIW82413.1 - 6.6e-11 41.7 0.9 2.3e-10 39.9 0.6 1.8 1 1 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EIW82413.1 - 0.00029 20.3 0.0 0.022 14.2 0.0 2.8 1 1 0 1 1 1 1 Signal peptidase, peptidase S26 Sugar_tr PF00083.19 EIW82414.1 - 8.2e-110 367.4 23.2 9.7e-110 367.2 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW82414.1 - 1.6e-26 92.8 32.9 1.2e-18 67.0 4.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EIW82414.1 - 3.4e-05 23.7 7.1 0.0048 16.8 0.6 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF1228) DUF697 PF05128.7 EIW82414.1 - 0.61 9.5 5.9 0.49 9.8 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF697) Herpes_LMP1 PF05297.6 EIW82414.1 - 1.9 7.3 6.8 3.4 6.5 4.7 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Sec63 PF02889.11 EIW82415.1 - 3.4e-71 240.0 0.0 6.6e-71 239.0 0.0 1.4 1 0 0 1 1 1 1 Sec63 Brl domain DEAD PF00270.24 EIW82415.1 - 5.9e-33 113.7 0.3 1.2e-29 103.0 0.1 3.3 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EIW82415.1 - 3.1e-08 33.6 0.0 7.7e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EIW82415.1 - 2.9e-07 30.2 0.0 7.7e-06 25.6 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EIW82415.1 - 2.4e-06 27.7 0.1 0.0026 17.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EIW82415.1 - 0.0058 16.1 0.0 2 7.7 0.0 3.0 2 1 0 3 3 3 1 AAA-like domain IstB_IS21 PF01695.12 EIW82415.1 - 0.049 13.0 0.2 9.9 5.5 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein RNA_helicase PF00910.17 EIW82415.1 - 0.13 12.4 0.0 0.63 10.2 0.0 2.1 2 0 0 2 2 2 0 RNA helicase Aminotran_1_2 PF00155.16 EIW82416.1 - 1.6e-66 224.7 0.0 1.8e-66 224.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EIW82416.1 - 4.8e-07 29.1 0.0 7.4e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EIW82416.1 - 1.5e-05 23.4 0.0 2.4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EIW82416.1 - 6e-05 22.3 0.0 8.7e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EIW82416.1 - 0.0017 17.1 0.0 0.098 11.3 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Ank_2 PF12796.2 EIW82417.1 - 3e-28 97.9 0.0 1.1e-14 54.4 0.0 2.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIW82417.1 - 1.6e-22 79.0 0.8 1.6e-11 44.0 0.0 4.4 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIW82417.1 - 6.6e-18 64.7 1.1 5.7e-07 29.8 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EIW82417.1 - 1.8e-17 62.1 0.1 1.2e-07 31.1 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EIW82417.1 - 2.9e-12 45.5 0.1 0.00039 20.4 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat zf-RING_2 PF13639.1 EIW82417.1 - 2.8e-05 23.8 2.9 0.0043 16.8 1.3 2.9 2 1 0 2 2 2 1 Ring finger domain FYVE PF01363.16 EIW82417.1 - 0.0036 17.1 4.9 0.0036 17.1 3.4 3.4 3 1 0 3 3 3 1 FYVE zinc finger PI31_Prot_N PF11566.3 EIW82419.1 - 3.5e-25 88.4 0.0 4.3e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EIW82419.1 - 1.2e-11 45.0 17.4 1.2e-11 45.0 12.1 3.4 3 0 0 3 3 3 1 PI31 proteasome regulator DEAD PF00270.24 EIW82420.1 - 1.8e-46 157.7 0.0 6.7e-46 155.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW82420.1 - 1.2e-23 82.7 0.0 2.9e-23 81.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EIW82420.1 - 0.0014 17.5 0.0 0.002 16.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EIW82420.1 - 0.025 14.3 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit CMS1 PF14617.1 EIW82420.1 - 0.069 12.2 0.1 0.21 10.6 0.0 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit MFS_1 PF07690.11 EIW82421.1 - 6.7e-42 143.4 36.6 6.7e-42 143.4 25.3 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EIW82421.1 - 1.3e-05 23.6 2.0 2.1e-05 22.9 1.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EIW82421.1 - 0.00019 19.6 0.8 0.00037 18.7 0.5 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector Nup88 PF10168.4 EIW82422.1 - 2.5e-21 75.2 0.0 4.5e-10 38.0 0.0 2.3 2 0 0 2 2 2 2 Nuclear pore component Proteasome PF00227.21 EIW82423.1 - 6.6e-46 155.9 0.0 8.2e-46 155.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIW82423.1 - 4.1e-13 48.3 0.1 7.3e-13 47.5 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SAC3_GANP PF03399.11 EIW82424.1 - 1e-34 119.9 0.0 1.6e-34 119.2 0.0 1.3 1 1 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EIW82424.1 - 2.2e-32 111.7 0.1 3.5e-32 111.1 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 Proteasome PF00227.21 EIW82425.1 - 6.8e-46 155.9 0.1 7.8e-46 155.7 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit OB_RNB PF08206.6 EIW82425.1 - 0.054 12.9 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease B OB domain GFO_IDH_MocA PF01408.17 EIW82427.1 - 1.2e-21 77.4 0.3 1.9e-21 76.7 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Saccharop_dh PF03435.13 EIW82427.1 - 7.1e-05 21.9 0.3 0.0001 21.4 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 EIW82427.1 - 0.061 13.7 0.0 0.19 12.1 0.0 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Rho_GDI PF02115.12 EIW82429.1 - 5e-49 166.4 0.0 5.9e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor PBP_dimer PF03717.10 EIW82429.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.2 1 0 0 1 1 1 0 Penicillin-binding Protein dimerisation domain UbiA PF01040.13 EIW82430.1 - 9.8e-35 120.0 17.6 1.4e-34 119.5 12.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ytp1 PF10355.4 EIW82431.1 - 5.3e-91 304.5 10.3 7.9e-91 304.0 7.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EIW82431.1 - 2.5e-13 49.5 0.2 2.5e-13 49.5 0.2 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) MFS_1 PF07690.11 EIW82432.1 - 6.6e-35 120.4 19.8 1e-34 119.8 13.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Wzy_C PF04932.10 EIW82433.1 - 0.0044 16.8 0.0 0.0079 15.9 0.0 1.4 1 0 0 1 1 1 1 O-Antigen ligase EphA2_TM PF14575.1 EIW82433.1 - 0.014 15.7 0.0 0.034 14.5 0.0 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DAG1 PF05454.6 EIW82433.1 - 0.029 13.5 0.0 0.029 13.5 0.0 1.9 2 0 0 2 2 2 0 Dystroglycan (Dystrophin-associated glycoprotein 1) DUF4013 PF13197.1 EIW82433.1 - 0.14 11.5 4.1 4.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4013) SSP160 PF06933.6 EIW82433.1 - 1.4 6.7 26.6 1.8 6.4 18.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PRCC PF10253.4 EIW82433.1 - 4.2 8.0 8.2 0.26 11.9 1.1 2.1 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting cNMP_binding PF00027.24 EIW82434.1 - 1.4e-38 130.5 0.0 1.7e-19 69.3 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain RIIa PF02197.12 EIW82434.1 - 9.8e-13 47.3 0.3 2.3e-12 46.1 0.2 1.6 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit Pkinase PF00069.20 EIW82435.1 - 9.4e-75 251.1 0.0 1.3e-74 250.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW82435.1 - 5.5e-36 123.9 0.1 1.2e-35 122.8 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW82435.1 - 0.0004 19.4 0.0 0.00088 18.3 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Phage_GPD PF05954.6 EIW82435.1 - 0.06 12.5 1.7 0.093 11.9 1.2 1.3 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) APH PF01636.18 EIW82435.1 - 0.16 11.6 0.0 0.16 11.6 0.0 2.6 2 1 0 2 2 2 0 Phosphotransferase enzyme family Med15 PF09606.5 EIW82435.1 - 1.5 6.9 39.5 2.1 6.4 27.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF935 PF06074.7 EIW82435.1 - 4.5 5.8 11.1 6.6 5.3 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) DUF605 PF04652.11 EIW82435.1 - 6.2 6.1 22.7 9.2 5.5 15.8 1.2 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 EIW82435.1 - 7.2 6.3 20.6 9.7 5.9 14.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Utp12 PF04003.7 EIW82436.1 - 7.3e-14 51.6 1.3 4.5e-13 49.0 0.9 2.0 1 1 0 1 1 1 1 Dip2/Utp12 Family UTP15_C PF09384.5 EIW82436.1 - 0.061 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 UTP15 C terminal ubiquitin PF00240.18 EIW82437.1 - 1.9e-06 27.1 0.0 3.2e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EIW82437.1 - 0.0079 16.3 0.0 0.042 14.0 0.0 2.2 3 0 0 3 3 3 1 DUF2407 ubiquitin-like domain GFO_IDH_MocA PF01408.17 EIW82438.1 - 3.1e-24 85.7 0.0 7e-24 84.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EIW82438.1 - 9.7e-07 28.5 0.0 1.8e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 EIW82438.1 - 0.0022 18.2 0.0 0.0036 17.6 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 EIW82438.1 - 0.039 14.3 0.1 0.071 13.5 0.0 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DapB_N PF01113.15 EIW82438.1 - 0.052 13.4 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Glyco_hydro_9 PF00759.14 EIW82439.1 - 2.6e-65 221.0 6.1 5.5e-65 220.0 4.3 1.4 1 1 0 1 1 1 1 Glycosyl hydrolase family 9 FAD_binding_1 PF00667.15 EIW82440.1 - 2.3e-49 167.7 0.0 3.5e-49 167.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EIW82440.1 - 3e-09 37.4 0.0 7.8e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Transketolase_C PF02780.15 EIW82440.1 - 0.043 13.7 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Transketolase, C-terminal domain FAD_binding_6 PF00970.19 EIW82440.1 - 0.12 12.4 0.0 0.4 10.8 0.0 1.8 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain CDC48_N PF02359.13 EIW82440.1 - 0.18 11.7 0.0 0.45 10.5 0.0 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), N-terminal domain UPRTase PF14681.1 EIW82441.1 - 9.5e-68 227.4 0.0 1.1e-67 227.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EIW82441.1 - 0.0013 18.4 0.0 0.0019 17.9 0.0 1.3 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Methyltransf_8 PF05148.10 EIW82442.1 - 7.2e-67 225.2 0.0 1.4e-66 224.3 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_23 PF13489.1 EIW82442.1 - 2.7e-07 30.4 0.0 4e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW82442.1 - 1e-06 29.0 0.0 5.1e-06 26.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW82442.1 - 3.9e-05 23.2 0.1 0.16 11.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EIW82442.1 - 0.0029 18.1 0.1 0.01 16.3 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW82442.1 - 0.0034 17.7 0.1 0.3 11.4 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW82442.1 - 0.0087 16.5 0.0 0.03 14.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW82442.1 - 0.042 12.9 0.0 0.17 10.9 0.0 2.1 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family AAA_10 PF12846.2 EIW82443.1 - 6.6e-12 45.4 0.3 1.4e-08 34.5 0.0 2.2 2 0 0 2 2 2 2 AAA-like domain Zot PF05707.7 EIW82443.1 - 5.5e-08 32.4 0.0 9.5e-07 28.4 0.0 2.2 2 0 0 2 2 2 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 EIW82443.1 - 0.00078 19.5 0.0 2 8.5 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA PF00004.24 EIW82443.1 - 0.0018 18.4 0.0 0.028 14.6 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 EIW82443.1 - 0.016 15.0 0.1 0.041 13.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EIW82443.1 - 0.052 13.0 0.0 0.72 9.2 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family GN3L_Grn1 PF08701.6 EIW82445.1 - 5e-21 74.3 15.5 5e-21 74.3 10.7 1.9 2 0 0 2 2 2 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EIW82445.1 - 4.6e-14 52.3 0.0 2.4e-10 40.3 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AIG1 PF04548.11 EIW82445.1 - 2.1e-06 26.9 0.0 6.3e-06 25.4 0.0 1.8 2 0 0 2 2 2 1 AIG1 family FeoB_N PF02421.13 EIW82445.1 - 3e-06 26.6 0.2 0.0008 18.7 0.0 2.7 2 1 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EIW82445.1 - 3.5e-05 23.0 0.0 6.6e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EIW82445.1 - 6.3e-05 22.8 5.4 0.0092 15.8 0.3 3.7 3 1 1 4 4 4 2 Dynamin family GTP_EFTU PF00009.22 EIW82445.1 - 0.00023 20.6 0.0 0.33 10.3 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EIW82445.1 - 0.00079 18.6 0.2 0.0023 17.2 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EIW82445.1 - 0.0028 18.1 0.0 0.25 11.8 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_29 PF13555.1 EIW82445.1 - 0.009 15.5 0.0 0.021 14.3 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Septin PF00735.13 EIW82445.1 - 0.016 14.2 0.0 0.031 13.3 0.0 1.4 1 0 0 1 1 1 0 Septin MobB PF03205.9 EIW82445.1 - 0.035 13.8 0.1 0.081 12.6 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B POPLD PF08170.7 EIW82445.1 - 0.56 10.0 2.6 0.83 9.5 0.8 2.0 1 1 0 1 1 1 0 POPLD (NUC188) domain RNA_pol_A_bac PF01000.21 EIW82446.1 - 2.5e-25 88.7 0.0 5e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EIW82446.1 - 1.6e-14 52.7 0.0 2.3e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain fn3 PF00041.16 EIW82446.1 - 0.041 14.0 0.0 0.08 13.0 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III domain VPS28 PF03997.7 EIW82447.1 - 0.049 13.2 0.0 0.061 12.9 0.0 1.1 1 0 0 1 1 1 0 VPS28 protein JmjC PF02373.17 EIW82448.1 - 3.4e-15 56.2 0.0 7.4e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_8 PF13621.1 EIW82448.1 - 4.3e-05 23.1 0.0 0.00018 21.0 0.0 2.0 1 1 0 1 1 1 1 Cupin-like domain C1_1 PF00130.17 EIW82448.1 - 0.025 14.2 2.8 0.074 12.7 1.9 1.8 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_2 PF14445.1 EIW82448.1 - 0.37 10.7 11.6 0.28 11.1 3.7 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 Response_reg PF00072.19 EIW82449.1 - 2.1e-23 82.4 0.0 2e-16 59.9 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain Orbi_NS1 PF01718.11 EIW82449.1 - 0.65 7.9 0.0 0.98 7.3 0.0 1.1 1 0 0 1 1 1 0 Orbivirus non-structural protein NS1, or hydrophobic tubular protein DUF3546 PF12066.3 EIW82450.1 - 5.7e-15 55.2 0.2 1.9e-14 53.6 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 EIW82450.1 - 2.8e-11 44.0 0.2 2.8e-11 44.0 0.1 2.7 3 0 0 3 3 3 1 Arsenite-resistance protein 2 DUF4187 PF13821.1 EIW82450.1 - 2.8e-05 23.6 0.5 6.2e-05 22.5 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) zf-C2H2_2 PF12756.2 EIW82450.1 - 0.014 15.5 2.8 3.1 7.9 0.0 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EIW82450.1 - 0.25 11.7 5.4 0.051 13.9 1.0 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type RRM_6 PF14259.1 EIW82451.1 - 1.6e-06 27.9 0.0 4.7e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIW82451.1 - 0.0011 18.5 0.0 0.068 12.8 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW82451.1 - 0.0062 16.3 0.0 0.037 13.8 0.0 2.1 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2414 PF10309.4 EIW82452.1 - 3.5e-07 29.7 0.0 6.6e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) FoP_duplication PF13865.1 EIW82452.1 - 0.014 15.7 1.9 0.014 15.7 1.3 2.7 3 0 0 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 KH_1 PF00013.24 EIW82453.1 - 9.1e-05 22.0 0.0 0.00018 21.1 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EIW82453.1 - 0.0024 17.4 0.0 0.0051 16.4 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_4 PF13083.1 EIW82453.1 - 0.0072 15.9 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 KH domain EAF PF09816.4 EIW82454.1 - 5.2e-22 77.8 0.0 1e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor CAF1A PF12253.3 EIW82454.1 - 0.011 15.8 0.8 0.011 15.8 0.5 2.8 3 0 0 3 3 3 0 Chromatin assembly factor 1 subunit A GET2 PF08690.5 EIW82454.1 - 0.1 11.8 1.2 0.21 10.7 0.8 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 Ferritin_2 PF13668.1 EIW82455.1 - 1.1e-35 122.5 0.9 1.1e-35 122.5 0.6 2.1 2 1 0 2 2 2 1 Ferritin-like domain Nop PF01798.13 EIW82456.1 - 4.5e-58 194.8 0.7 9.4e-58 193.7 0.5 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EIW82456.1 - 3.8e-28 97.0 0.3 6.7e-28 96.2 0.2 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EIW82456.1 - 1.1e-19 70.3 0.6 1.1e-19 70.3 0.4 2.1 2 0 0 2 2 2 1 NOP5NT (NUC127) domain Nucleo_P87 PF07267.6 EIW82456.1 - 0.11 11.2 8.5 0.16 10.6 5.9 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 adh_short PF00106.20 EIW82457.1 - 0.00097 19.0 0.1 9.4 6.1 0.1 3.4 1 1 1 3 3 3 2 short chain dehydrogenase 7TM_GPCR_Srx PF10328.4 EIW82457.1 - 0.3 10.1 3.9 0.095 11.7 0.4 1.8 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srx ATP_bind_3 PF01171.15 EIW82458.1 - 4.8e-18 65.2 0.0 1e-17 64.2 0.0 1.5 2 0 0 2 2 2 1 PP-loop family DUF2392 PF10288.4 EIW82458.1 - 0.0047 17.2 0.0 0.012 15.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2392) Asn_synthase PF00733.16 EIW82458.1 - 0.016 14.6 0.0 0.035 13.6 0.0 1.5 2 0 0 2 2 2 0 Asparagine synthase RecR PF02132.10 EIW82458.1 - 0.031 13.6 1.3 0.031 13.6 0.9 2.8 4 0 0 4 4 4 0 RecR protein DUF3936 PF13072.1 EIW82458.1 - 0.098 12.1 1.6 0.29 10.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3936) DUF2616 PF11077.3 EIW82458.1 - 0.4 10.1 5.8 0.88 9.0 0.4 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) Ribosomal_L37e PF01907.14 EIW82458.1 - 1.4 8.8 6.2 1.3 8.8 1.6 2.6 2 0 0 2 2 2 0 Ribosomal protein L37e PUF PF00806.14 EIW82459.1 - 1.5e-09 36.8 0.0 0.021 14.2 0.0 6.9 7 0 0 7 7 7 4 Pumilio-family RNA binding repeat Abhydrolase_6 PF12697.2 EIW82460.1 - 7.1e-25 88.2 0.1 1.1e-24 87.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW82460.1 - 6.8e-11 42.1 0.0 1.5e-10 40.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Bystin PF05291.6 EIW82461.1 - 8.3e-122 405.8 0.0 1.2e-121 405.3 0.0 1.1 1 0 0 1 1 1 1 Bystin Epimerase PF01370.16 EIW82462.1 - 4e-42 144.2 0.0 5.5e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIW82462.1 - 4.3e-11 42.2 0.0 4.3e-10 38.9 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EIW82462.1 - 1.3e-09 37.2 0.0 2e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EIW82462.1 - 3.4e-09 35.9 0.1 3.7e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EIW82462.1 - 7.2e-05 22.8 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EIW82462.1 - 0.00014 20.9 0.2 0.054 12.3 0.1 3.0 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein UXS1_N PF11803.3 EIW82462.1 - 0.02 14.6 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal adh_short PF00106.20 EIW82462.1 - 0.037 13.9 0.2 0.22 11.4 0.1 2.0 2 0 0 2 2 2 0 short chain dehydrogenase DGCR6 PF07324.6 EIW82463.1 - 1.6e-08 34.2 2.8 4.7e-08 32.7 1.9 1.7 1 1 0 1 1 1 1 DiGeorge syndrome critical region 6 (DGCR6) protein DUF2458 PF10454.4 EIW82463.1 - 3.9e-08 33.3 0.7 5.7e-08 32.7 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2458) Phage_Mu_Gam PF07352.7 EIW82463.1 - 0.03 13.8 0.3 0.079 12.4 0.2 1.7 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein RGS PF00615.14 EIW82464.1 - 5.8e-34 116.7 0.3 1.9e-33 115.0 0.0 2.1 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.16 EIW82464.1 - 3.6e-12 45.8 0.1 7.4e-07 28.8 0.0 3.4 2 1 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Cyt-b5 PF00173.23 EIW82465.1 - 2.4e-08 33.6 0.1 4.7e-08 32.7 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Nup160 PF11715.3 EIW82466.1 - 3e-32 111.4 0.0 7.8e-32 110.1 0.0 1.6 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Fungal_trans PF04082.13 EIW82467.1 - 3.1e-21 75.4 1.7 3.1e-21 75.4 1.2 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW82467.1 - 3.2e-05 23.7 8.7 5.7e-05 22.9 6.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.8 EIW82467.1 - 8.8 6.1 17.9 0.78 9.5 3.9 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Aldo_ket_red PF00248.16 EIW82468.1 - 7.5e-43 146.3 0.0 9.3e-43 146.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family B12D PF06522.6 EIW82469.1 - 9.7e-13 47.6 0.4 1.4e-12 47.0 0.3 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF2353 PF09789.4 EIW82470.1 - 0.012 14.8 3.8 0.022 14.0 2.6 1.4 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Isochorismatase PF00857.15 EIW82471.1 - 1.1e-27 97.1 0.0 1.9e-27 96.3 0.0 1.4 1 1 0 1 1 1 1 Isochorismatase family PhoH PF02562.11 EIW82471.1 - 0.088 12.0 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein DAD PF02109.11 EIW82472.1 - 9.2e-49 164.2 0.7 1e-48 164.0 0.5 1.0 1 0 0 1 1 1 1 DAD family Adap_comp_sub PF00928.16 EIW82473.1 - 4.6e-50 170.1 0.0 5.7e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EIW82473.1 - 5.5e-05 22.9 0.0 9.2e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Hexokinase_1 PF00349.16 EIW82474.1 - 1.5e-63 213.8 0.0 2.9e-63 212.9 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EIW82474.1 - 4.4e-63 212.7 0.0 9.2e-63 211.6 0.0 1.5 1 1 0 1 1 1 1 Hexokinase bZIP_1 PF00170.16 EIW82475.1 - 6e-11 42.1 9.2 1.1e-10 41.2 6.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor Aft1_HRA PF11786.3 EIW82475.1 - 3.6e-09 36.7 16.8 3.6e-09 36.7 11.6 3.6 2 1 0 2 2 2 1 Aft1 HRA domain Aft1_OSA PF11785.3 EIW82475.1 - 9.9e-08 32.4 7.2 9.9e-08 32.4 5.0 3.8 3 2 2 5 5 5 1 Aft1 osmotic stress response (OSM) domain bZIP_2 PF07716.10 EIW82475.1 - 4.5e-06 26.3 9.8 1.1e-05 25.1 6.8 1.7 1 0 0 1 1 1 1 Basic region leucine zipper Phlebovirus_NSM PF07246.6 EIW82475.1 - 1.9 7.5 4.5 2.9 6.9 3.1 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Mt_ATP-synt_D PF05873.7 EIW82476.1 - 1.5e-10 40.9 0.7 1.7e-10 40.7 0.5 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) LsmAD PF06741.8 EIW82476.1 - 0.013 15.5 0.9 3.1 7.9 0.0 2.2 2 0 0 2 2 2 0 LsmAD domain DUF2730 PF10805.3 EIW82476.1 - 0.026 14.2 0.8 4.2 7.1 0.0 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF2730) GAS PF13851.1 EIW82476.1 - 0.045 12.9 2.5 0.067 12.3 1.7 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1327 PF07041.6 EIW82476.1 - 0.077 12.9 0.2 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) FAM110_C PF14160.1 EIW82476.1 - 0.085 13.7 0.0 0.18 12.7 0.0 1.5 1 1 0 1 1 1 0 Centrosome-associated C terminus DUF2580 PF10824.3 EIW82476.1 - 0.19 12.0 1.6 0.66 10.3 0.0 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2580) DUF2838 PF10998.3 EIW82477.1 - 4.5e-37 126.3 8.1 9.1e-37 125.3 5.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2838) GET2 PF08690.5 EIW82477.1 - 0.35 10.0 3.4 0.63 9.2 2.3 1.4 1 0 0 1 1 1 0 GET complex subunit GET2 A_deamin PF02137.13 EIW82478.1 - 1.5e-78 264.5 0.0 1.9e-78 264.1 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain DUF4452 PF14618.1 EIW82479.1 - 0.11 12.3 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4452) EutN_CcmL PF03319.8 EIW82479.1 - 0.14 12.5 0.1 0.27 11.6 0.1 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutN/carboxysome Methyltransf_16 PF10294.4 EIW82482.1 - 8.4e-44 149.0 0.0 1e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EIW82482.1 - 4.4e-06 27.2 0.0 6.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW82482.1 - 0.00027 20.3 0.0 0.00041 19.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EIW82482.1 - 0.01 15.8 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EIW82482.1 - 0.012 14.8 0.0 0.016 14.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EIW82482.1 - 0.039 13.5 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EIW82482.1 - 0.045 12.9 0.1 0.07 12.2 0.1 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB BolA PF01722.13 EIW82483.1 - 1.4e-16 60.2 0.0 1.8e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein COX15-CtaA PF02628.10 EIW82484.1 - 4.8e-89 298.2 13.3 5.8e-89 297.9 9.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein Proteasome PF00227.21 EIW82485.1 - 9.8e-54 181.5 0.0 1.4e-53 180.9 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIW82485.1 - 2.8e-12 45.6 0.0 2.8e-12 45.6 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature GAS PF13851.1 EIW82486.1 - 0.071 12.3 20.6 0.013 14.6 10.8 1.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF3770 PF12603.3 EIW82486.1 - 0.34 9.9 10.0 0.5 9.4 6.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3770) APG6 PF04111.7 EIW82486.1 - 0.94 8.4 15.3 1.3 8.0 10.6 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 YjcZ PF13990.1 EIW82486.1 - 3.6 6.6 14.0 8.5 5.4 9.7 1.6 1 1 0 1 1 1 0 YjcZ-like protein IncA PF04156.9 EIW82486.1 - 5.8 6.4 19.4 14 5.2 13.5 1.6 1 1 0 1 1 1 0 IncA protein MS_channel PF00924.13 EIW82487.1 - 1.7e-21 76.4 0.6 2.7e-21 75.8 0.4 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_6 PF13405.1 EIW82487.1 - 0.0024 17.5 0.0 0.0087 15.8 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.27 EIW82487.1 - 0.0039 16.3 0.0 0.0039 16.3 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 EIW82487.1 - 0.022 14.0 0.1 0.049 13.0 0.1 1.6 1 0 0 1 1 1 0 EF hand EF-hand_8 PF13833.1 EIW82487.1 - 0.025 14.1 0.0 0.06 12.9 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_7 PF13499.1 EIW82487.1 - 0.073 13.2 0.1 0.073 13.2 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain pair GTP_EFTU PF00009.22 EIW82489.1 - 6.4e-33 113.7 0.0 8.9e-33 113.3 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EIW82489.1 - 3.6e-07 30.2 0.0 5.4e-06 26.5 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EIW82489.1 - 2e-06 27.7 0.5 4.8e-06 26.5 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EIW82489.1 - 4.8e-05 22.9 0.0 8.5e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EIW82489.1 - 0.023 14.6 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase Pex2_Pex12 PF04757.9 EIW82491.1 - 1.5e-52 178.3 2.1 2.2e-52 177.7 1.4 1.2 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region Ank_2 PF12796.2 EIW82491.1 - 6.7e-44 148.1 5.3 1.5e-13 50.8 0.5 4.2 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EIW82491.1 - 3.8e-36 121.1 9.0 4.2e-05 23.1 0.3 7.7 7 0 0 7 7 7 7 Ankyrin repeat Ank_4 PF13637.1 EIW82491.1 - 1.8e-24 85.6 4.3 9.2e-09 35.5 0.1 5.1 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EIW82491.1 - 1.9e-24 85.1 12.5 2e-05 24.6 0.4 8.0 1 1 6 7 7 7 7 Ankyrin repeats (many copies) SPX PF03105.14 EIW82491.1 - 2e-22 80.2 0.0 1.7e-20 73.9 0.0 2.4 2 0 0 2 2 2 1 SPX domain Ank_3 PF13606.1 EIW82491.1 - 2.4e-21 73.6 4.4 0.0055 16.8 0.0 7.8 7 0 0 7 7 7 5 Ankyrin repeat GDPD PF03009.12 EIW82491.1 - 2.2e-08 33.9 0.0 0.01 15.3 0.0 3.3 1 1 0 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family zf-C3HC4_3 PF13920.1 EIW82491.1 - 7.6e-06 25.4 0.2 1.5e-05 24.5 0.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW82491.1 - 1.8e-05 24.5 0.1 3.8e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIW82491.1 - 4.1e-05 23.4 0.4 8.6e-05 22.4 0.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Serglycin PF04360.7 EIW82491.1 - 0.11 12.2 4.3 0.28 10.9 3.0 1.7 1 0 0 1 1 1 0 Serglycin B2 PF11473.3 EIW82491.1 - 0.16 11.6 0.1 0.5 9.9 0.0 1.9 2 0 0 2 2 1 0 RNA binding protein B2 CENP-B_dimeris PF09026.5 EIW82491.1 - 0.35 11.1 7.1 0.84 9.9 4.9 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-C3HC4_4 PF15227.1 EIW82491.1 - 0.38 10.6 0.9 0.81 9.6 0.6 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-dskA_traR PF01258.12 EIW82491.1 - 0.55 10.0 4.0 0.49 10.1 1.5 1.9 2 0 0 2 2 1 0 Prokaryotic dksA/traR C4-type zinc finger Nucleoplasmin PF03066.10 EIW82491.1 - 6.8 6.1 7.3 12 5.4 5.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin DUF829 PF05705.9 EIW82492.1 - 1.3e-31 110.1 0.0 2.2e-31 109.3 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 EIW82492.1 - 0.00023 21.1 0.4 0.0003 20.7 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family MIP PF00230.15 EIW82493.1 - 5.2e-46 156.9 17.4 6.7e-46 156.5 12.1 1.1 1 0 0 1 1 1 1 Major intrinsic protein NfeD PF01957.13 EIW82493.1 - 0.27 11.3 15.4 0.64 10.1 2.3 2.6 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding ABC_tran PF00005.22 EIW82494.1 - 4.7e-24 85.2 0.0 8.8e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIW82494.1 - 5.6e-09 36.3 0.0 0.00016 21.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EIW82494.1 - 6.7e-05 22.2 0.0 0.36 10.0 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_13 PF13166.1 EIW82494.1 - 6.7e-05 21.5 0.1 0.076 11.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EIW82494.1 - 0.00068 18.7 0.0 0.12 11.3 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.1 EIW82494.1 - 0.0027 17.7 0.2 0.016 15.2 0.0 2.3 3 0 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 EIW82494.1 - 0.0035 18.1 0.0 0.0081 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EIW82494.1 - 0.0049 16.0 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EIW82494.1 - 0.005 16.7 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EIW82494.1 - 0.0075 15.7 0.1 0.019 14.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF87 PF01935.12 EIW82494.1 - 0.0085 15.9 0.1 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF87 AAA_22 PF13401.1 EIW82494.1 - 0.01 16.0 0.0 0.48 10.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 EIW82494.1 - 0.044 14.1 0.1 0.076 13.3 0.1 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EIW82494.1 - 0.047 13.4 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EIW82494.1 - 0.053 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIW82494.1 - 0.054 13.8 0.0 0.34 11.2 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.1 EIW82494.1 - 0.074 12.6 0.0 0.16 11.5 0.0 1.4 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EIW82494.1 - 0.098 12.0 0.0 0.35 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain GTP_cyclohydroI PF01227.17 EIW82495.1 - 3.1e-75 251.3 0.7 3.5e-75 251.2 0.5 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EIW82495.1 - 0.00014 21.7 0.0 0.00052 19.9 0.0 1.9 2 0 0 2 2 2 1 QueF-like protein HATPase_c_2 PF13581.1 EIW82495.1 - 0.014 15.1 0.1 0.024 14.4 0.1 1.4 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Tho2 PF11262.3 EIW82496.1 - 1.9e-64 217.5 0.0 2.7e-64 217.0 0.0 1.2 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EIW82496.1 - 6.4e-27 93.1 0.0 1.3e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Acyltransferase PF01553.16 EIW82497.1 - 2.9e-19 68.8 0.0 4.4e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase MRC1 PF09444.5 EIW82499.1 - 2.2e-15 57.2 22.4 2.2e-15 57.2 15.5 5.8 3 2 3 6 6 6 2 MRC1-like domain Ribosomal_L3 PF00297.17 EIW82500.1 - 1.1e-120 401.9 7.3 1.3e-120 401.7 5.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 AMMECR1 PF01871.12 EIW82501.1 - 6.4e-41 139.3 0.0 1e-29 102.8 0.0 2.0 2 0 0 2 2 2 2 AMMECR1 Ras PF00071.17 EIW82502.1 - 3.7e-43 146.7 0.0 1.4e-39 135.0 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EIW82502.1 - 1.2e-16 61.2 0.0 2.3e-16 60.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW82502.1 - 6e-10 38.6 0.0 1.9e-09 37.0 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EIW82502.1 - 0.00067 19.5 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EIW82502.1 - 0.016 14.4 0.4 0.23 10.6 0.0 2.4 2 1 1 3 3 3 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EIW82502.1 - 0.1 11.7 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Ribosomal_S7e PF01251.13 EIW82503.1 - 1.4e-83 279.0 4.0 2.7e-83 278.1 2.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S7e TPR_11 PF13414.1 EIW82503.1 - 2.7e-20 71.7 1.8 4.3e-15 55.1 0.1 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EIW82503.1 - 2.4e-16 58.5 3.5 1.7e-05 24.2 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIW82503.1 - 5.3e-12 44.6 2.3 0.00033 20.3 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIW82503.1 - 2.2e-05 23.8 1.0 0.047 13.4 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIW82503.1 - 7.3e-05 23.0 0.1 0.28 11.9 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIW82503.1 - 9.3e-05 21.9 0.3 0.22 11.4 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIW82503.1 - 0.00038 20.3 1.3 0.77 9.7 0.3 2.6 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIW82503.1 - 0.00039 20.6 0.2 0.1 12.9 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIW82503.1 - 0.0018 18.8 0.1 0.94 10.2 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EIW82503.1 - 0.003 17.6 2.5 0.003 17.6 1.7 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF3808 PF10300.4 EIW82503.1 - 0.0051 15.4 0.7 0.0083 14.7 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_10 PF13374.1 EIW82503.1 - 0.017 15.0 0.2 5 7.1 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIW82503.1 - 0.025 15.0 1.4 4.1 8.0 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIW82503.1 - 0.08 12.8 0.1 0.31 10.9 0.1 2.0 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 EIW82503.1 - 0.55 10.5 2.8 4.6 7.6 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DAO PF01266.19 EIW82504.1 - 1.8e-38 132.3 0.0 2.4e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW82504.1 - 0.043 13.8 0.0 0.089 12.8 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NDUFA12 PF05071.11 EIW82505.1 - 1.2e-16 61.0 0.3 1.5e-16 60.7 0.2 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 SH3_1 PF00018.23 EIW82506.1 - 7.2e-20 70.1 0.0 1.1e-09 37.5 0.0 3.0 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EIW82506.1 - 7.5e-18 63.8 0.0 5.4e-09 35.5 0.0 2.9 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EIW82506.1 - 1.5e-13 49.9 0.0 4.2e-07 29.3 0.0 2.7 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 EIW82506.1 - 1.4e-07 31.3 0.0 3e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 EIW82506.1 - 0.0002 20.9 0.4 0.00066 19.2 0.0 1.9 2 0 0 2 2 2 1 PB1 domain Not3 PF04065.10 EIW82507.1 - 5.1e-93 310.6 18.2 7.5e-93 310.0 12.6 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EIW82507.1 - 5.4e-43 146.0 8.4 1.9e-42 144.3 5.8 2.0 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Syntaxin PF00804.20 EIW82507.1 - 0.0072 16.4 12.3 1.9 8.6 5.8 2.7 1 1 1 2 2 2 2 Syntaxin CDC45 PF02724.9 EIW82507.1 - 0.035 12.1 7.0 0.065 11.2 4.9 1.4 1 0 0 1 1 1 0 CDC45-like protein Cep57_MT_bd PF06657.8 EIW82507.1 - 0.1 12.5 4.9 0.042 13.8 0.7 2.4 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF2373 PF10180.4 EIW82507.1 - 0.18 11.3 2.6 0.44 10.1 1.8 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2373) Ribosomal_L12 PF00542.14 EIW82508.1 - 1.4e-18 66.6 6.1 1.1e-17 63.8 3.2 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain p450 PF00067.17 EIW82510.1 - 1.8e-57 194.9 0.0 2e-57 194.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 COMPASS-Shg1 PF05205.7 EIW82511.1 - 3.4e-12 46.5 0.0 3.5e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 COMPASS (Complex proteins associated with Set1p) component shg1 DUF3772 PF12607.3 EIW82511.1 - 0.66 9.6 3.0 7.2 6.3 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3772) URO-D PF01208.12 EIW82512.1 - 4.3e-124 413.9 0.0 4.8e-124 413.7 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Ank_2 PF12796.2 EIW82513.1 - 4.2e-21 75.0 0.4 2.7e-09 37.2 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EIW82513.1 - 4.5e-20 70.3 0.2 5.4e-09 35.4 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EIW82513.1 - 8.3e-17 60.8 0.4 4.9e-07 29.7 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIW82513.1 - 8.4e-16 58.0 0.4 8.4e-10 38.9 0.0 3.9 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIW82513.1 - 4.2e-15 54.3 0.4 8.7e-05 22.4 0.0 5.2 5 0 0 5 5 5 2 Ankyrin repeat KilA-N PF04383.8 EIW82513.1 - 0.00011 21.7 0.0 0.0009 18.8 0.0 2.3 1 1 0 1 1 1 1 KilA-N domain Acyl-CoA_dh_C PF12806.2 EIW82513.1 - 0.0041 16.9 0.9 0.39 10.5 0.0 2.7 2 0 0 2 2 2 1 Acetyl-CoA dehydrogenase C-terminal like RasGAP PF00616.14 EIW82513.1 - 0.036 13.7 0.6 1 8.9 0.0 2.2 2 0 0 2 2 2 0 GTPase-activator protein for Ras-like GTPase IncA PF04156.9 EIW82513.1 - 0.28 10.7 5.6 2 8.0 1.1 2.3 2 0 0 2 2 2 0 IncA protein N36 PF11438.3 EIW82514.1 - 0.084 12.3 0.1 0.084 12.3 0.1 4.2 4 0 0 4 4 4 0 36-mer N-terminal peptide of the N protein (N36) Nucleoside_tran PF01733.13 EIW82515.1 - 1.7e-34 119.3 5.3 1.7e-34 119.3 3.7 2.5 1 1 1 2 2 2 1 Nucleoside transporter DUF202 PF02656.10 EIW82515.1 - 8.6 6.6 15.9 1.6 9.0 2.0 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF202) Vfa1 PF08432.5 EIW82516.1 - 1.9e-36 125.8 8.1 2.1e-36 125.6 5.6 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 Atrophin-1 PF03154.10 EIW82516.1 - 0.01 14.0 8.9 0.013 13.7 6.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family RXT2_N PF08595.6 EIW82516.1 - 0.12 12.2 4.1 0.18 11.5 2.9 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal FLO_LFY PF01698.11 EIW82516.1 - 0.12 11.2 4.2 0.14 10.9 2.9 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein U79_P34 PF03064.11 EIW82516.1 - 0.13 11.8 10.8 0.14 11.6 7.5 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Ycf1 PF05758.7 EIW82516.1 - 0.39 8.3 6.0 0.39 8.3 4.2 1.0 1 0 0 1 1 1 0 Ycf1 DUF4407 PF14362.1 EIW82516.1 - 0.62 8.9 5.3 0.77 8.6 3.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1510 PF07423.6 EIW82516.1 - 0.66 9.3 15.0 0.92 8.8 10.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 EIW82516.1 - 0.68 7.8 10.2 0.78 7.6 7.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3987 PF13148.1 EIW82516.1 - 2.2 6.7 8.0 2.8 6.4 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) NPR3 PF03666.8 EIW82516.1 - 2.6 6.4 9.4 3.1 6.2 6.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF1168 PF06658.7 EIW82516.1 - 3 7.3 22.4 0.5 9.8 12.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1168) NARP1 PF12569.3 EIW82516.1 - 3.2 6.4 13.1 4.2 6.0 9.1 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4557 PF15101.1 EIW82516.1 - 7.4 6.3 9.4 22 4.7 6.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4557) Paramyxo_ncap PF00973.14 EIW82516.1 - 7.5 5.1 6.1 8.1 5.0 4.3 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein ADH_N PF08240.7 EIW82517.1 - 4.1e-27 94.1 1.9 8.4e-27 93.0 1.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW82517.1 - 3.2e-18 65.5 0.2 5.8e-18 64.7 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIW82517.1 - 0.00045 19.4 0.1 0.00081 18.5 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ThiF PF00899.16 EIW82517.1 - 0.088 12.6 0.9 0.25 11.1 0.4 1.9 2 0 0 2 2 2 0 ThiF family Tox-WTIP PF15654.1 EIW82518.1 - 0.037 13.6 0.3 0.058 13.0 0.2 1.3 1 0 0 1 1 1 0 Toxin with a conserved tryptophan and TIP tripeptide motif dUTPase PF00692.14 EIW82519.1 - 4.5e-40 136.0 0.0 5.6e-40 135.7 0.0 1.1 1 0 0 1 1 1 1 dUTPase Sugar_tr PF00083.19 EIW82521.1 - 1.6e-94 317.0 23.7 1.8e-94 316.8 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW82521.1 - 2.9e-30 105.1 41.3 3.3e-22 78.6 11.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EIW82521.1 - 0.5 10.1 0.0 0.5 10.1 0.0 4.9 5 1 1 6 6 6 0 MFS_1 like family DUF2530 PF10745.4 EIW82521.1 - 3.3 7.7 8.9 0.15 12.0 0.7 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) adh_short PF00106.20 EIW82522.1 - 2.8e-23 82.6 1.2 3.7e-23 82.2 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW82522.1 - 1.7e-21 77.1 0.0 2.2e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW82522.1 - 3.9e-06 26.6 0.1 6.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EIW82522.1 - 0.039 13.6 0.2 0.15 11.6 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EIW82522.1 - 0.094 12.5 0.6 0.26 11.1 0.4 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF962 PF06127.6 EIW82523.1 - 6.4e-24 83.6 1.4 1.3e-23 82.6 1.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) Longin PF13774.1 EIW82524.1 - 9.4e-29 98.8 0.1 1.4e-28 98.2 0.0 1.2 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EIW82524.1 - 1.7e-15 56.4 0.0 2.6e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Synaptobrevin DUF1664 PF07889.7 EIW82524.1 - 0.093 12.5 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4646 PF15496.1 EIW82525.1 - 1.2e-19 70.5 0.2 7.7e-19 67.9 0.1 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4646) SR-25 PF10500.4 EIW82525.1 - 0.00011 21.7 9.3 0.00011 21.7 6.4 2.2 2 0 0 2 2 2 2 Nuclear RNA-splicing-associated protein Peptidase_S49_N PF08496.5 EIW82525.1 - 0.16 11.7 16.2 0.59 9.9 3.2 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal LCD1 PF09798.4 EIW82525.1 - 3.3 5.5 6.5 5.1 4.9 4.5 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein IF-2B PF01008.12 EIW82526.1 - 1.1e-85 287.1 0.1 1.6e-85 286.5 0.1 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family Phostensin_N PF13916.1 EIW82526.1 - 0.079 12.9 9.1 0.62 10.0 1.5 2.5 1 1 1 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal DUF2992 PF11208.3 EIW82526.1 - 0.28 11.1 12.9 0.053 13.4 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) SR-25 PF10500.4 EIW82526.1 - 2.7 7.4 22.1 4 6.8 15.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TFIIA PF03153.8 EIW82526.1 - 3.4 7.4 16.8 4.5 7.0 11.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fork_head PF00250.13 EIW82527.1 - 3.3e-22 78.3 0.2 5.8e-22 77.5 0.1 1.3 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EIW82527.1 - 1e-06 28.7 0.0 1.8e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 FHA domain Alpha_GJ PF03229.8 EIW82527.1 - 3.9 7.8 25.5 44 4.4 1.4 3.7 3 0 0 3 3 3 0 Alphavirus glycoprotein J IPK PF03770.11 EIW82529.1 - 8.5e-51 172.3 0.0 1.5e-50 171.6 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase UCR_UQCRX_QCR9 PF05365.7 EIW82530.1 - 3.1e-25 87.5 4.0 3.4e-25 87.4 2.7 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF1725 PF08333.6 EIW82530.1 - 1.5 8.2 3.4 17 4.8 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1725) Ribosomal_S11 PF00411.14 EIW82531.1 - 2.5e-05 24.4 0.0 3.3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S11 BcrAD_BadFG PF01869.15 EIW82531.1 - 0.007 15.6 0.0 0.0075 15.5 0.0 1.1 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family Flavokinase PF01687.12 EIW82532.1 - 5.7e-37 126.3 0.0 6.7e-37 126.1 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase Myb_DNA-binding PF00249.26 EIW82533.1 - 1.6e-42 143.3 8.4 2.8e-11 43.2 0.1 5.2 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIW82533.1 - 4.3e-39 132.4 4.8 1.4e-15 57.0 0.6 5.1 2 2 3 5 5 5 5 Myb-like DNA-binding domain Rap1_C PF11626.3 EIW82533.1 - 0.00023 20.9 5.2 0.46 10.3 1.3 3.7 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_4 PF13837.1 EIW82533.1 - 0.00082 19.4 16.4 0.032 14.3 0.2 5.8 4 3 0 4 4 4 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EIW82533.1 - 0.0078 16.0 2.7 0.064 13.1 0.3 3.3 4 1 1 5 5 5 1 Myb/SANT-like DNA-binding domain DUF3440 PF11922.3 EIW82533.1 - 0.074 12.6 0.1 0.21 11.1 0.0 1.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3440) DUF3253 PF11625.3 EIW82533.1 - 0.08 12.8 0.3 0.16 11.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3253) DUF788 PF05620.6 EIW82534.1 - 3.9e-42 144.0 0.0 4.3e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Cons_hypoth698 PF03601.9 EIW82534.1 - 0.13 10.8 0.1 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 698 YMF19 PF02326.10 EIW82534.1 - 0.17 12.4 1.6 0.18 12.4 0.1 1.7 2 0 0 2 2 2 0 Plant ATP synthase F0 FAM101 PF15068.1 EIW82535.1 - 0.023 14.1 11.4 0.02 14.3 3.2 2.7 2 1 1 3 3 3 0 FAM101 family adh_short PF00106.20 EIW82536.1 - 1e-05 25.5 0.0 1.7e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW82536.1 - 0.1 12.3 0.0 0.15 11.8 0.0 1.4 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Abhydrolase_6 PF12697.2 EIW82537.1 - 9.9e-33 113.9 0.9 1.5e-32 113.3 0.2 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW82537.1 - 4.4e-19 68.9 0.0 1.3e-14 54.3 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW82537.1 - 6.9e-15 55.0 0.1 6.6e-10 38.9 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Esterase PF00756.15 EIW82537.1 - 2e-05 24.1 0.1 4.2e-05 23.1 0.1 1.7 1 1 0 1 1 1 1 Putative esterase Ndr PF03096.9 EIW82537.1 - 0.0014 17.2 0.0 0.0045 15.5 0.0 1.7 2 0 0 2 2 2 1 Ndr family BAAT_C PF08840.6 EIW82537.1 - 0.0015 18.2 0.0 0.72 9.5 0.0 2.1 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal DUF2305 PF10230.4 EIW82537.1 - 0.0016 17.8 0.0 0.0039 16.6 0.0 1.6 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 EIW82537.1 - 0.0018 18.0 0.0 0.004 16.9 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Ser_hydrolase PF06821.8 EIW82537.1 - 0.0057 16.2 0.0 0.0096 15.5 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_3 PF07859.8 EIW82537.1 - 0.013 15.1 0.0 0.069 12.7 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EIW82537.1 - 0.14 11.5 0.0 11 5.3 0.0 2.7 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase cwf21 PF08312.7 EIW82538.1 - 3.7e-15 55.4 8.8 3.7e-15 55.4 6.1 3.1 2 1 2 4 4 4 1 cwf21 domain DUF605 PF04652.11 EIW82538.1 - 2.9 7.2 21.9 4.2 6.6 15.2 1.2 1 0 0 1 1 1 0 Vta1 like Aminotran_3 PF00202.16 EIW82539.1 - 7.9e-88 294.5 0.0 1e-87 294.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EIW82539.1 - 0.02 13.8 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II Aminotran_1_2 PF00155.16 EIW82540.1 - 1.1e-74 251.6 0.0 1.4e-74 251.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EIW82540.1 - 1.9e-05 23.5 0.0 7e-05 21.7 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EIW82540.1 - 3e-05 22.4 0.0 5.1e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Methyltransf_31 PF13847.1 EIW82540.1 - 0.12 11.9 0.0 0.34 10.4 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Asp PF00026.18 EIW82541.1 - 2.9e-47 161.4 2.8 3.4e-47 161.2 1.9 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EIW82541.1 - 1.5e-05 25.3 5.5 0.28 11.7 0.0 3.4 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EIW82541.1 - 0.00049 19.6 1.0 0.016 14.7 0.7 2.3 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EIW82541.1 - 0.0093 15.7 0.4 2.7 7.8 0.0 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP PF00077.15 EIW82541.1 - 0.096 12.6 1.0 1.6 8.6 0.2 2.5 2 0 0 2 2 2 0 Retroviral aspartyl protease DUF2373 PF10180.4 EIW82542.1 - 6.6e-18 64.0 0.3 9.8e-18 63.4 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) MIP-T3 PF10243.4 EIW82542.1 - 0.0016 16.9 13.7 0.0019 16.7 9.5 1.0 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 CDC45 PF02724.9 EIW82542.1 - 0.42 8.5 10.0 0.57 8.1 6.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 EIW82542.1 - 2.3 5.7 11.3 3 5.4 7.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Sec62 PF03839.11 EIW82542.1 - 5.8 6.2 11.0 7.7 5.8 7.6 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 FAM60A PF15396.1 EIW82542.1 - 9 5.9 11.6 6.2 6.4 7.0 1.5 2 0 0 2 2 2 0 Protein Family FAM60A bZIP_1 PF00170.16 EIW82544.1 - 0.0083 16.0 4.3 0.033 14.1 2.7 2.1 2 0 0 2 2 2 1 bZIP transcription factor DUF904 PF06005.7 EIW82544.1 - 0.19 12.0 7.3 0.21 11.8 3.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Glyco_hydro_61 PF03443.9 EIW82545.1 - 1.5e-17 64.1 0.4 1.7e-17 64.0 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Peroxidase_2 PF01328.12 EIW82546.1 - 3.1e-22 78.6 0.0 6.1e-22 77.7 0.0 1.4 1 1 0 1 1 1 1 Peroxidase, family 2 RhoGAP PF00620.22 EIW82547.1 - 1.9e-29 102.2 0.0 3.3e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain MyTH4 PF00784.12 EIW82547.1 - 1.2e-25 89.7 0.0 2.2e-25 88.8 0.0 1.4 1 0 0 1 1 1 1 MyTH4 domain WW PF00397.21 EIW82547.1 - 4.6e-12 45.5 9.3 8.3e-08 31.9 4.5 2.6 2 0 0 2 2 2 2 WW domain SAMP PF05924.6 EIW82547.1 - 0.016 14.3 0.7 0.04 13.0 0.5 1.7 1 0 0 1 1 1 0 SAMP Motif DUF3824 PF12868.2 EIW82548.1 - 0.018 15.9 0.0 0.059 14.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Peptidase_C26 PF07722.8 EIW82548.1 - 0.056 12.8 0.0 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Peptidase C26 BTB PF00651.26 EIW82549.1 - 6.1e-05 22.9 0.0 0.00014 21.8 0.0 1.5 1 1 0 1 1 1 1 BTB/POZ domain 3-alpha PF03475.9 EIW82549.1 - 0.44 10.2 4.1 3.9 7.2 0.4 2.7 2 0 0 2 2 2 0 3-alpha domain DUF1932 PF09130.6 EIW82550.1 - 3.6e-13 49.0 0.0 7.3e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.10 EIW82550.1 - 7.8e-11 42.0 0.0 1.2e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EIW82550.1 - 0.0016 17.8 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EIW82550.1 - 0.0026 18.1 0.0 0.0081 16.5 0.0 1.8 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ATP-synt_ab PF00006.20 EIW82550.1 - 0.096 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain 2-Hacid_dh_C PF02826.14 EIW82550.1 - 0.12 11.5 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F-box-like PF12937.2 EIW82551.1 - 0.027 14.1 0.2 0.25 11.1 0.0 2.6 2 0 0 2 2 2 0 F-box-like ECH PF00378.15 EIW82552.1 - 1.1e-79 267.0 0.6 1.4e-79 266.7 0.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EIW82552.1 - 0.0021 17.8 0.1 0.011 15.4 0.0 2.0 2 0 0 2 2 2 1 Peptidase family S49 ECH_C PF13766.1 EIW82552.1 - 0.019 15.1 0.2 0.052 13.6 0.1 1.8 2 1 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region HET PF06985.6 EIW82553.1 - 2.6e-22 79.4 0.0 4.7e-22 78.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box PF00646.28 EIW82554.1 - 0.0018 17.9 0.1 0.0037 16.8 0.1 1.5 1 0 0 1 1 1 1 F-box domain p450 PF00067.17 EIW82555.1 - 1.3e-67 228.3 0.0 2.4e-67 227.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 HEAT PF02985.17 EIW82556.1 - 1e-11 43.8 0.3 0.32 11.2 0.0 6.3 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 EIW82556.1 - 1.6e-06 28.3 0.2 0.032 14.5 0.0 4.2 2 1 2 4 4 4 3 HEAT repeats Pkinase_Tyr PF07714.12 EIW82556.1 - 0.0018 17.3 0.0 0.0031 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 EIW82556.1 - 0.0024 18.3 2.9 0.58 10.7 0.0 4.8 3 2 2 5 5 5 1 HEAT-like repeat Pkinase PF00069.20 EIW82556.1 - 0.011 14.8 0.0 0.026 13.6 0.0 1.4 1 1 0 1 1 1 0 Protein kinase domain Adaptin_N PF01602.15 EIW82556.1 - 0.12 10.6 0.0 0.51 8.6 0.0 1.8 1 1 1 2 2 2 0 Adaptin N terminal region Tropomyosin PF00261.15 EIW82557.1 - 0.031 13.3 15.4 0.33 10.0 2.0 2.1 1 1 1 2 2 2 0 Tropomyosin CENP-Q PF13094.1 EIW82557.1 - 0.16 11.9 11.4 0.024 14.6 4.1 2.2 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TMCO5 PF14992.1 EIW82557.1 - 9.7 5.2 7.5 14 4.6 5.2 1.2 1 0 0 1 1 1 0 TMCO5 family Ank PF00023.25 EIW82558.1 - 3.9e-13 48.4 5.7 6.3e-09 35.2 0.2 2.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EIW82558.1 - 3.4e-12 46.5 0.1 1.3e-11 44.7 0.0 1.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EIW82558.1 - 5.4e-09 35.4 0.8 0.00017 21.4 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EIW82558.1 - 1.9e-08 34.5 0.7 9.6e-07 29.1 0.4 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EIW82558.1 - 1.5e-07 31.4 2.4 0.0042 17.2 0.1 2.4 2 1 0 2 2 2 2 Ankyrin repeats (many copies) GST_C_3 PF14497.1 EIW82560.1 - 9e-06 26.0 0.0 2.1e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW82560.1 - 5.6e-05 23.0 0.0 9.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIW82560.1 - 0.0029 17.4 0.1 0.0066 16.3 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIW82560.1 - 0.0039 17.3 0.0 0.013 15.6 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PRK PF00485.13 EIW82561.1 - 0.0049 16.4 0.1 0.0077 15.8 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EIW82561.1 - 0.015 15.5 0.2 0.026 14.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain FAD_binding_2 PF00890.19 EIW82562.1 - 5.4e-88 295.6 0.7 6.8e-88 295.3 0.5 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EIW82562.1 - 2.3e-22 78.5 0.1 6.5e-22 77.1 0.0 1.9 2 0 0 2 2 1 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EIW82562.1 - 4.2e-13 48.9 0.3 9.3e-10 37.9 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW82562.1 - 8.8e-10 38.4 1.5 3.3e-09 36.6 0.1 2.8 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIW82562.1 - 3.4e-09 36.8 0.7 2.2e-07 30.9 0.5 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIW82562.1 - 6.2e-08 32.1 2.0 1.1e-07 31.3 1.4 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EIW82562.1 - 1.7e-07 30.6 0.1 2.9e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EIW82562.1 - 3e-06 26.3 1.4 8.3e-05 21.6 0.7 2.2 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EIW82562.1 - 4.7e-06 26.8 0.1 9.4e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW82562.1 - 8.8e-05 21.1 0.6 8.8e-05 21.1 0.4 2.7 4 0 0 4 4 4 1 HI0933-like protein Thi4 PF01946.12 EIW82562.1 - 0.0002 20.5 2.4 0.005 15.9 0.4 2.6 3 0 0 3 3 3 1 Thi4 family Amino_oxidase PF01593.19 EIW82562.1 - 0.0016 17.5 0.4 0.0055 15.8 0.2 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EIW82562.1 - 0.0047 17.3 1.2 0.049 14.0 0.2 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIW82562.1 - 0.0048 15.8 0.3 0.028 13.3 0.2 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EIW82562.1 - 0.015 15.0 0.3 0.21 11.3 0.2 2.3 1 1 0 1 1 1 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EIW82562.1 - 0.02 15.1 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EIW82562.1 - 0.046 13.2 0.0 0.14 11.7 0.2 1.6 2 0 0 2 2 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EIW82562.1 - 0.15 11.6 0.3 0.26 10.9 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain APG5 PF04106.7 EIW82563.1 - 9.5e-47 159.0 0.0 1.2e-46 158.7 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 Acetyltransf_3 PF13302.1 EIW82567.1 - 3.3e-09 37.0 0.0 4.1e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW82567.1 - 0.022 14.7 0.1 0.087 12.8 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family DASH_Dad2 PF08654.5 EIW82568.1 - 1.5e-09 37.7 0.0 2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 DASH complex subunit Dad2 Zn_clus PF00172.13 EIW82569.1 - 1.3e-07 31.3 8.6 1.3e-07 31.3 6.0 2.6 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.1 EIW82569.1 - 5.7e-07 29.5 2.5 5.7e-07 29.5 1.8 4.7 5 0 0 5 5 5 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIW82569.1 - 8.5e-05 22.6 4.8 8.5e-05 22.6 3.4 4.6 4 0 0 4 4 4 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIW82569.1 - 0.00047 20.3 15.9 0.0019 18.4 3.1 4.7 5 0 0 5 5 5 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EIW82569.1 - 0.0047 16.7 2.1 0.0047 16.7 1.5 3.5 4 0 0 4 4 4 1 C2H2-type zinc finger zf-met PF12874.2 EIW82569.1 - 0.044 13.9 3.9 5.3 7.3 0.1 3.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.10 EIW82569.1 - 0.14 11.9 5.9 4.5 7.1 4.1 2.9 1 1 0 1 1 1 0 BED zinc finger zf-C2H2_jaz PF12171.3 EIW82569.1 - 1.9 8.7 9.4 1.3 9.2 0.2 3.2 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding DUF2039 PF10217.4 EIW82569.1 - 2.2 8.3 11.4 13 5.9 4.1 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) Hydrolase_6 PF13344.1 EIW82570.1 - 2.3e-22 78.7 0.0 6.6e-22 77.2 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIW82570.1 - 8.6e-22 76.6 0.1 2.5e-21 75.1 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EIW82570.1 - 4.1e-07 30.3 0.0 0.00013 22.2 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIW82570.1 - 1.5e-05 25.5 0.0 0.17 12.3 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Glyco_tran_WecB PF03808.8 EIW82570.1 - 0.071 12.5 0.0 0.56 9.5 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase WecB/TagA/CpsF family DUF1996 PF09362.5 EIW82571.1 - 9.6e-59 198.8 0.3 1.5e-58 198.2 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) YCII PF03795.9 EIW82572.1 - 4.9e-10 39.4 0.0 6.3e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain YCII PF03795.9 EIW82573.1 - 7.5e-07 29.2 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 YCII-related domain DUF1996 PF09362.5 EIW82574.1 - 1.9e-78 263.3 0.3 2.5e-78 262.9 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) SNARE_assoc PF09335.6 EIW82575.1 - 0.04 14.1 0.0 0.072 13.2 0.0 1.3 1 0 0 1 1 1 0 SNARE associated Golgi protein IncA PF04156.9 EIW82575.1 - 0.077 12.5 0.3 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 IncA protein DUF2959 PF11172.3 EIW82575.1 - 0.24 11.1 9.2 1 9.1 3.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) Borrelia_REV PF03978.8 EIW82575.1 - 0.28 10.8 1.8 0.42 10.3 1.2 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein HlyD_2 PF12700.2 EIW82575.1 - 0.45 9.6 9.9 0.55 9.3 6.9 1.2 1 0 0 1 1 1 0 HlyD family secretion protein SCIMP PF15050.1 EIW82575.1 - 4.9 7.0 5.5 2.4 8.0 1.5 2.0 2 0 0 2 2 2 0 SCIMP protein HrpF PF06266.7 EIW82575.1 - 8 6.6 8.2 7.8 6.7 2.1 2.7 1 1 1 2 2 2 0 HrpF protein DEAD PF00270.24 EIW82576.1 - 5.5e-17 61.7 0.4 8.1e-11 41.7 0.0 3.6 3 1 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW82576.1 - 3.7e-11 42.7 0.0 7.5e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW82576.1 - 0.003 17.3 0.0 0.011 15.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF3663 PF12404.3 EIW82576.1 - 0.057 13.1 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Peptidase FAD_binding_3 PF01494.14 EIW82579.1 - 4.9e-76 256.0 0.0 6.5e-76 255.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EIW82579.1 - 0.00049 19.3 0.0 0.0008 18.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EIW82579.1 - 0.00064 18.3 0.0 0.0017 16.9 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EIW82579.1 - 0.0022 17.9 0.0 0.021 14.7 0.0 2.4 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW82579.1 - 0.0035 16.2 0.0 0.013 14.3 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EIW82579.1 - 0.0041 16.2 0.0 0.0072 15.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EIW82579.1 - 0.0045 15.8 0.0 0.0079 15.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIW82579.1 - 0.0082 16.1 0.0 0.026 14.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EIW82579.1 - 0.015 14.1 0.0 0.026 13.3 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EIW82579.1 - 0.02 13.5 0.0 0.044 12.4 0.0 1.5 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 EIW82579.1 - 0.046 13.7 0.1 0.17 11.8 0.1 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW82579.1 - 0.11 12.9 0.0 1.8 8.9 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NACHT PF05729.7 EIW82580.1 - 4.5e-08 32.9 0.6 1.3e-07 31.4 0.1 2.1 3 0 0 3 3 3 1 NACHT domain AAA_16 PF13191.1 EIW82580.1 - 1.3e-07 31.7 0.2 2.6e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW82580.1 - 0.003 17.7 0.0 0.0082 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EIW82580.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase PRK PF00485.13 EIW82580.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Arch_ATPase PF01637.13 EIW82580.1 - 0.022 14.4 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase NB-ARC PF00931.17 EIW82580.1 - 0.026 13.3 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EIW82580.1 - 0.032 14.4 0.0 0.062 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase SFTA2 PF15210.1 EIW82580.1 - 0.075 12.6 0.1 0.2 11.2 0.1 1.8 1 0 0 1 1 1 0 Surfactant-associated protein 2 DUF2075 PF09848.4 EIW82580.1 - 0.077 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Zeta_toxin PF06414.7 EIW82580.1 - 0.078 12.0 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin PIF1 PF05970.9 EIW82580.1 - 0.089 11.7 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 PIF1-like helicase CAP PF00188.21 EIW82581.1 - 4.2e-05 24.0 0.6 6e-05 23.5 0.4 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Shisa PF13908.1 EIW82581.1 - 0.084 13.0 0.0 0.099 12.8 0.0 1.0 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator RRM_1 PF00076.17 EIW82582.1 - 1.9e-22 78.6 0.0 2.3e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW82582.1 - 3.4e-20 71.7 0.0 4.1e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW82582.1 - 5.3e-11 42.1 0.0 6.7e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ABC_tran PF00005.22 EIW82583.1 - 2e-36 125.2 0.0 4.2e-36 124.2 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EIW82583.1 - 4.3e-24 85.3 3.7 6e-24 84.8 2.6 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EIW82583.1 - 2.2e-07 31.1 0.0 0.0018 18.2 0.0 2.3 1 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 EIW82583.1 - 2e-05 23.9 0.0 0.00026 20.2 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EIW82583.1 - 0.00038 20.4 0.2 0.0016 18.4 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EIW82583.1 - 0.0013 18.1 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EIW82583.1 - 0.0031 17.6 0.1 0.019 15.1 0.1 2.2 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EIW82583.1 - 0.0041 16.3 0.0 0.0085 15.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EIW82583.1 - 0.092 11.8 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin SbcCD_C PF13558.1 EIW82583.1 - 0.1 12.5 0.3 1.1 9.2 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 EIW82583.1 - 0.14 12.1 0.0 0.56 10.1 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.1 EIW82583.1 - 0.18 12.1 0.0 0.44 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF4191 PF13829.1 EIW82583.1 - 0.22 10.5 1.8 0.54 9.3 1.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) RRM_1 PF00076.17 EIW82584.1 - 1.8e-24 85.1 0.0 2.1e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW82584.1 - 1.7e-17 63.1 0.0 2e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW82584.1 - 3.1e-14 52.5 0.0 3.9e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1264 PF06884.6 EIW82585.1 - 4.2e-68 228.0 0.9 4.7e-68 227.9 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) Homez PF11569.3 EIW82585.1 - 0.075 12.1 0.1 3.1 6.9 0.0 2.4 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez RRM_1 PF00076.17 EIW82586.1 - 1.9e-11 43.3 0.0 2.4e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW82586.1 - 1e-08 35.0 0.0 1.3e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW82586.1 - 6.2e-06 25.9 0.0 9.3e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EIW82586.1 - 0.00018 21.3 0.0 0.00022 21.0 0.0 1.1 1 0 0 1 1 1 1 RNA binding motif Limkain-b1 PF11608.3 EIW82586.1 - 0.00047 19.8 0.0 0.00049 19.7 0.0 1.2 1 0 0 1 1 1 1 Limkain b1 RNA_bind PF08675.6 EIW82586.1 - 0.058 13.3 0.0 0.071 13.0 0.0 1.1 1 0 0 1 1 1 0 RNA binding domain Nup35_RRM_2 PF14605.1 EIW82586.1 - 0.096 12.4 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif HMG_box PF00505.14 EIW82589.1 - 1.6e-14 53.9 1.9 1.6e-14 53.9 1.3 2.5 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIW82589.1 - 1.3e-06 28.6 0.4 1.3e-06 28.6 0.3 2.4 1 1 1 2 2 2 1 HMG-box domain FAM91_C PF14648.1 EIW82590.1 - 0.13 11.0 4.6 0.32 9.7 0.1 2.1 2 0 0 2 2 2 0 FAM91 C-terminus Sds3 PF08598.6 EIW82590.1 - 0.39 10.2 10.8 0.051 13.1 3.3 2.2 2 0 0 2 2 2 0 Sds3-like Transposase_21 PF02992.9 EIW82591.1 - 1.7e-06 27.2 0.0 3.6e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EIW82591.1 - 0.025 14.0 0.3 0.051 13.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) Daxx PF03344.10 EIW82591.1 - 9.3 4.5 10.9 16 3.8 7.6 1.3 1 0 0 1 1 1 0 Daxx Family FAD_binding_3 PF01494.14 EIW82592.1 - 6e-77 259.0 0.0 7.7e-77 258.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EIW82592.1 - 0.001 18.2 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EIW82592.1 - 0.0014 17.2 0.1 0.0034 15.9 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EIW82592.1 - 0.003 16.6 0.0 0.0049 15.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EIW82592.1 - 0.0099 14.8 0.0 0.019 13.8 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIW82592.1 - 0.012 15.4 0.7 0.13 12.1 0.5 2.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW82592.1 - 0.012 15.5 0.0 0.035 14.1 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIW82592.1 - 0.018 13.8 0.0 0.041 12.7 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EIW82592.1 - 0.045 12.6 0.0 0.072 11.9 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EIW82592.1 - 0.052 12.1 0.2 0.14 10.7 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 EIW82592.1 - 0.077 13.0 0.0 0.19 11.7 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIW82593.1 - 9.1e-65 219.0 0.0 1.5e-64 218.3 0.0 1.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EIW82593.1 - 0.00045 20.1 0.0 0.0047 16.8 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW82593.1 - 0.0024 17.8 0.0 0.0054 16.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIW82593.1 - 0.005 15.9 0.0 0.0092 15.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EIW82593.1 - 0.0062 15.0 0.0 0.011 14.1 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EIW82593.1 - 0.0072 15.2 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIW82593.1 - 0.019 13.9 0.0 0.037 12.9 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIW82593.1 - 0.021 14.9 0.0 0.054 13.5 0.0 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW82593.1 - 0.06 13.7 0.0 1.1 9.7 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIW82593.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding BNR PF02012.15 EIW82594.1 - 0.025 14.3 2.4 0.054 13.3 0.1 2.4 2 0 0 2 2 2 0 BNR/Asp-box repeat BNR PF02012.15 EIW82596.1 - 0.0013 18.2 0.0 0.0032 17.0 0.0 1.7 1 0 0 1 1 1 1 BNR/Asp-box repeat ALS_ss_C PF10369.4 EIW82597.1 - 1.7e-20 72.4 0.1 7.7e-19 67.2 0.0 2.4 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 EIW82597.1 - 1.1e-12 47.1 0.1 2.3e-12 46.1 0.1 1.6 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EIW82597.1 - 2e-09 37.0 0.0 4e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 ACT domain FAD_binding_3 PF01494.14 EIW82598.1 - 3.3e-73 246.7 0.0 4.7e-73 246.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EIW82598.1 - 4.1e-06 26.9 0.0 8.7e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW82598.1 - 3.3e-05 22.9 0.1 0.099 11.5 0.0 3.0 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW82598.1 - 9.3e-05 22.7 0.0 0.24 11.8 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW82598.1 - 0.00045 18.8 0.0 0.034 12.6 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.2 EIW82598.1 - 0.00054 19.1 0.0 0.0017 17.5 0.0 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIW82598.1 - 0.0037 17.1 0.0 0.033 14.0 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW82598.1 - 0.025 14.6 0.0 0.06 13.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIW82598.1 - 0.035 12.9 0.0 0.2 10.4 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 EIW82598.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GspL_C PF12693.2 EIW82599.1 - 0.034 13.8 0.4 0.081 12.6 0.3 1.6 1 0 0 1 1 1 0 GspL periplasmic domain DUF1218 PF06749.7 EIW82599.1 - 0.4 11.1 5.4 6.8 7.2 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) FAD_binding_3 PF01494.14 EIW82601.1 - 3.9e-68 230.1 0.0 5e-68 229.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIW82601.1 - 2.8e-05 24.0 0.0 6.6e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIW82601.1 - 0.00016 21.8 0.0 0.00071 19.6 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW82601.1 - 0.00027 20.8 0.0 0.0017 18.2 0.0 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW82601.1 - 0.00039 19.5 0.0 0.00068 18.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EIW82601.1 - 0.00062 18.7 0.0 0.0044 15.9 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EIW82601.1 - 0.00065 18.6 0.1 0.03 13.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EIW82601.1 - 0.00081 17.9 0.0 0.0023 16.4 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EIW82601.1 - 0.0023 18.2 0.0 0.48 10.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIW82601.1 - 0.022 14.5 0.1 0.065 12.9 0.0 2.0 2 1 0 2 2 2 0 FAD-NAD(P)-binding BNR PF02012.15 EIW82603.1 - 0.063 13.1 0.1 0.2 11.5 0.0 1.9 1 0 0 1 1 1 0 BNR/Asp-box repeat Pkinase PF00069.20 EIW82604.1 - 1.2e-57 194.9 0.1 2.5e-57 193.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW82604.1 - 6.1e-29 100.8 0.0 8.7e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW82604.1 - 0.00018 20.5 0.0 0.00035 19.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF4407 PF14362.1 EIW82604.1 - 1 8.2 7.3 1.8 7.4 5.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DDHD PF02862.12 EIW82604.1 - 7.7 6.2 7.3 21 4.7 5.1 1.8 1 0 0 1 1 1 0 DDHD domain F-box-like PF12937.2 EIW82607.1 - 3.5e-05 23.4 0.2 9.5e-05 22.0 0.1 1.8 1 0 0 1 1 1 1 F-box-like Phage_Treg PF04761.7 EIW82607.1 - 0.034 13.9 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Lactococcus bacteriophage putative transcription regulator Apidaecin PF00807.12 EIW82607.1 - 0.17 11.5 5.6 0.28 10.8 3.9 1.3 1 0 0 1 1 1 0 Apidaecin F-box PF00646.28 EIW82607.1 - 0.29 10.8 4.1 1.6 8.5 1.0 3.1 2 1 0 2 2 2 0 F-box domain FAD_binding_3 PF01494.14 EIW82608.1 - 4.1e-81 272.7 0.0 5e-81 272.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EIW82608.1 - 6.8e-06 25.3 0.0 1.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EIW82608.1 - 4.7e-05 23.3 0.1 0.00014 21.8 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIW82608.1 - 0.00015 20.8 0.0 0.0016 17.4 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIW82608.1 - 0.00016 21.6 0.1 0.0039 17.0 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIW82608.1 - 0.0002 20.5 0.5 0.00047 19.3 0.4 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_10 PF13460.1 EIW82608.1 - 0.00027 21.0 0.3 0.39 10.7 0.0 2.6 3 0 0 3 3 3 2 NADH(P)-binding FAD_binding_2 PF00890.19 EIW82608.1 - 0.00038 19.4 1.1 0.00093 18.1 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EIW82608.1 - 0.0011 19.3 0.0 0.061 13.7 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW82608.1 - 0.0023 18.0 0.0 0.0048 16.9 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW82608.1 - 0.0027 16.2 0.1 0.0056 15.1 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 EIW82608.1 - 0.09 11.3 0.1 0.17 10.4 0.0 1.5 2 0 0 2 2 2 0 Tryptophan halogenase Lycopene_cycl PF05834.7 EIW82608.1 - 0.095 11.6 0.3 0.49 9.2 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein adh_short PF00106.20 EIW82611.1 - 1.9e-20 73.4 1.9 2.6e-20 72.9 1.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW82611.1 - 3.3e-11 43.4 0.0 4.9e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW82611.1 - 5.5e-06 26.1 0.2 9.6e-06 25.3 0.2 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIW82611.1 - 1.5e-05 25.1 0.4 3.2e-05 24.0 0.3 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW82611.1 - 0.00091 18.7 0.1 0.009 15.4 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EIW82611.1 - 0.01 15.5 0.0 0.021 14.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ARPC4 PF05856.7 EIW82614.1 - 1.6e-74 248.8 5.5 1.8e-74 248.7 3.8 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) FKBP_C PF00254.23 EIW82615.1 - 4.7e-30 103.4 1.7 5.7e-30 103.1 0.0 2.0 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase SR-25 PF10500.4 EIW82615.1 - 0.015 14.7 19.6 0.022 14.2 13.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein adh_short PF00106.20 EIW82618.1 - 2.6e-11 43.7 0.4 3e-11 43.5 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW82618.1 - 7.5e-05 22.6 0.0 9e-05 22.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EIW82618.1 - 0.00035 20.6 0.2 0.00039 20.4 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EIW82618.1 - 0.00048 19.8 0.2 0.00071 19.2 0.1 1.2 1 0 0 1 1 1 1 KR domain p450 PF00067.17 EIW82619.1 - 5.1e-52 176.9 0.0 2.8e-43 148.1 0.0 3.0 1 1 2 3 3 3 3 Cytochrome P450 DUF2811 PF10929.3 EIW82619.1 - 0.099 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2811) Sugar_tr PF00083.19 EIW82622.1 - 1.3e-82 277.8 21.4 1.5e-82 277.5 14.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW82622.1 - 3.2e-22 78.7 42.8 1.1e-14 54.0 10.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EIW82622.1 - 0.0012 18.8 8.8 0.0014 18.6 0.8 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) Tmem26 PF09772.4 EIW82623.1 - 0.011 14.9 0.5 0.014 14.6 0.3 1.1 1 0 0 1 1 1 0 Transmembrane protein 26 Peptidase_M54 PF07998.6 EIW82624.1 - 4.7e-11 42.8 0.5 7.5e-11 42.1 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M54 Peptidase_M10 PF00413.19 EIW82624.1 - 0.0048 16.6 0.0 0.0074 16.0 0.0 1.4 1 1 0 1 1 1 1 Matrixin Reprolysin_2 PF13574.1 EIW82624.1 - 0.018 15.0 0.2 0.12 12.4 0.1 2.1 2 1 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EIW82624.1 - 0.02 15.4 0.1 0.093 13.2 0.0 2.1 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EIW82624.1 - 0.08 12.8 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 Peptidase_M43 PF05572.8 EIW82624.1 - 0.09 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A Metallopep PF12044.3 EIW82624.1 - 0.18 10.2 0.4 0.28 9.6 0.3 1.1 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M66 PF10462.4 EIW82624.1 - 0.2 10.5 0.0 0.32 9.8 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 p450 PF00067.17 EIW82626.1 - 6.6e-66 222.7 0.0 1.4e-65 221.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 NTP_transferase PF00483.18 EIW82627.1 - 4.1e-40 137.6 0.0 1.1e-39 136.2 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EIW82627.1 - 2.9e-07 30.7 0.1 5.7e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain MannoseP_isomer PF01050.13 EIW82627.1 - 0.00036 20.1 0.1 0.00057 19.5 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase IspD PF01128.14 EIW82627.1 - 0.018 14.5 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase DivIC PF04977.10 EIW82627.1 - 0.1 12.1 0.7 0.18 11.3 0.1 1.7 2 0 0 2 2 2 0 Septum formation initiator DUF364 PF04016.7 EIW82627.1 - 0.15 11.3 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF364) SpaB_C PF14028.1 EIW82628.1 - 0.071 12.6 2.4 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 SpaB C-terminal domain Pox_A_type_inc PF04508.7 EIW82628.1 - 0.12 12.2 2.4 0.18 11.6 0.8 2.0 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat TATR PF03430.8 EIW82628.1 - 1 7.8 7.3 1.3 7.6 5.1 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator CENP-H PF05837.7 EIW82628.1 - 1.8 8.7 5.2 3.1 7.9 3.6 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF4094 PF13334.1 EIW82628.1 - 3.5 8.0 5.8 6.8 7.1 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) Transket_pyr PF02779.19 EIW82629.1 - 2.7e-66 222.4 0.0 4.3e-66 221.7 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EIW82629.1 - 2.9e-55 187.1 0.0 3.9e-55 186.6 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component PAS_8 PF13188.1 EIW82630.1 - 0.027 14.3 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 PAS domain Aldo_ket_red PF00248.16 EIW82631.1 - 8.5e-51 172.4 0.0 1.2e-50 171.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Peptidase_C12 PF01088.16 EIW82632.1 - 3.4e-53 179.9 0.0 5.8e-53 179.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Med31 PF05669.7 EIW82633.1 - 6.8e-35 118.9 5.7 8.7e-35 118.5 4.0 1.1 1 0 0 1 1 1 1 SOH1 Nod_GRP PF07806.6 EIW82633.1 - 1.1 8.9 4.8 8.3 6.1 0.1 2.6 3 0 0 3 3 3 0 Nodule-specific GRP repeat TPT PF03151.11 EIW82634.1 - 1.9e-28 99.0 7.5 1.9e-28 99.0 5.2 2.4 3 0 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EIW82634.1 - 5.4e-10 38.6 16.1 7.1e-10 38.2 11.1 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EIW82634.1 - 2.5e-06 27.5 30.1 0.00097 19.1 7.4 2.5 2 1 0 2 2 2 2 EamA-like transporter family DUF1129 PF06570.6 EIW82634.1 - 5.2 6.3 12.6 2.9 7.1 1.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1129) DUF2721 PF11026.3 EIW82634.1 - 5.6 6.6 11.3 16 5.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) EmrE PF13536.1 EIW82634.1 - 9.5 6.4 26.6 1.7 8.8 4.4 3.2 2 2 1 3 3 3 0 Multidrug resistance efflux transporter Zn_clus PF00172.13 EIW82635.1 - 3.6e-06 26.7 11.9 5.7e-06 26.1 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EIW82635.1 - 4.9e-06 25.6 0.1 6.8e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF581 PF04570.9 EIW82638.1 - 0.82 9.0 0.0 0.82 9.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF581) DUF2083 PF09856.4 EIW82638.1 - 2.1 8.0 4.8 1.5 8.4 0.6 2.1 1 1 1 2 2 2 0 Predicted transcriptional regulator (DUF2083) FeS PF04060.8 EIW82638.1 - 3.6 7.2 6.3 1.8 8.2 0.8 2.5 2 0 0 2 2 2 0 Putative Fe-S cluster Med12 PF09497.5 EIW82639.1 - 1.3e-26 92.3 0.0 3.1e-26 91.1 0.0 1.7 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 zf-RING_2 PF13639.1 EIW82640.1 - 1.1e-06 28.2 5.7 2.8e-05 23.8 2.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIW82640.1 - 3e-06 27.1 2.3 3e-06 27.1 1.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW82640.1 - 1.3e-05 24.7 2.5 0.00046 19.8 0.9 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EIW82640.1 - 1.9e-05 24.2 2.1 3.4e-05 23.4 0.5 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EIW82640.1 - 3.7e-05 23.3 1.3 3.7e-05 23.3 0.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW82640.1 - 0.00035 20.1 4.1 0.0033 17.0 0.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EIW82640.1 - 0.0006 19.5 0.1 0.0014 18.3 0.1 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein DivIC PF04977.10 EIW82640.1 - 0.0028 17.0 0.1 0.0053 16.2 0.0 1.3 1 0 0 1 1 1 1 Septum formation initiator zf-C3HC4_4 PF15227.1 EIW82640.1 - 0.0042 16.9 2.3 0.0042 16.9 1.6 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EIW82640.1 - 0.012 15.7 1.2 0.035 14.2 0.1 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger TMF_DNA_bd PF12329.3 EIW82640.1 - 0.12 12.2 2.0 2.1 8.2 0.2 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding zf-MIZ PF02891.15 EIW82640.1 - 0.6 9.6 4.2 2.3 7.7 1.1 2.4 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger FANCL_C PF11793.3 EIW82640.1 - 2.1 8.3 7.7 0.97 9.4 2.4 2.4 2 1 0 2 2 2 0 FANCL C-terminal domain F-box-like PF12937.2 EIW82641.1 - 0.0038 16.9 0.0 0.014 15.0 0.0 2.1 1 0 0 1 1 1 1 F-box-like IncA PF04156.9 EIW82642.1 - 0.0033 17.0 2.0 0.0048 16.5 1.4 1.2 1 0 0 1 1 1 1 IncA protein CENP-F_leu_zip PF10473.4 EIW82642.1 - 0.0043 16.9 8.2 0.0063 16.3 5.7 1.2 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.6 EIW82642.1 - 0.0051 15.3 5.5 0.0065 14.9 3.2 1.5 2 0 0 2 2 2 1 Weak chloroplast movement under blue light ATG16 PF08614.6 EIW82642.1 - 0.015 15.1 6.8 0.029 14.2 4.7 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Laminin_II PF06009.7 EIW82642.1 - 0.02 14.6 0.5 0.035 13.8 0.3 1.3 1 0 0 1 1 1 0 Laminin Domain II Filament PF00038.16 EIW82642.1 - 0.03 13.7 8.8 0.043 13.2 6.1 1.1 1 0 0 1 1 1 0 Intermediate filament protein DUF869 PF05911.6 EIW82642.1 - 0.035 12.3 2.9 0.049 11.8 2.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Tropomyosin PF00261.15 EIW82642.1 - 0.048 12.7 11.7 0.081 12.0 8.1 1.2 1 0 0 1 1 1 0 Tropomyosin GAS PF13851.1 EIW82642.1 - 0.08 12.1 4.6 0.12 11.5 3.2 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding APG6 PF04111.7 EIW82642.1 - 0.089 11.8 4.1 0.13 11.2 2.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 ERM PF00769.14 EIW82642.1 - 0.12 11.8 15.6 0.068 12.6 5.0 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Tropomyosin_1 PF12718.2 EIW82642.1 - 0.14 11.9 9.7 0.27 11.0 6.7 1.3 1 0 0 1 1 1 0 Tropomyosin like Lebercilin PF15619.1 EIW82642.1 - 0.27 10.6 10.7 0.41 10.0 7.4 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DMPK_coil PF08826.5 EIW82642.1 - 0.3 11.0 8.7 0.1 12.4 1.9 2.3 1 1 1 2 2 2 0 DMPK coiled coil domain like ADIP PF11559.3 EIW82642.1 - 0.86 9.4 8.8 1.5 8.7 6.1 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF2968 PF11180.3 EIW82642.1 - 1 8.7 8.8 1.7 7.9 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) ATP-synt_B PF00430.13 EIW82642.1 - 1.2 8.8 5.9 1.1 9.0 2.5 1.8 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) TPR_MLP1_2 PF07926.7 EIW82642.1 - 1.5 8.5 5.9 2.8 7.6 4.1 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein GAGA PF09237.6 EIW82643.1 - 0.056 13.0 2.3 0.12 11.9 1.6 1.5 1 0 0 1 1 1 0 GAGA factor Pmp3 PF01679.12 EIW82645.1 - 1.5 8.5 9.0 1.7 8.4 1.1 3.2 3 0 0 3 3 3 0 Proteolipid membrane potential modulator Metallophos PF00149.23 EIW82649.1 - 9.3e-08 31.7 4.7 1.1e-06 28.2 3.3 2.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIW82649.1 - 0.0011 18.8 0.0 0.0063 16.3 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain WD40 PF00400.27 EIW82650.1 - 3.6e-22 77.3 1.2 8.5e-08 31.8 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat Gmad1 PF10647.4 EIW82650.1 - 2.3e-05 23.9 2.5 0.00079 18.9 0.2 3.2 3 0 0 3 3 3 1 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 EIW82650.1 - 0.0011 18.5 0.4 1.6 8.4 0.0 4.8 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Chitin_synth_1 PF01644.12 EIW82657.1 - 4.4e-79 263.9 0.1 6.8e-79 263.3 0.0 1.3 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 EIW82657.1 - 6.1e-25 87.6 7.3 1.2e-19 70.1 0.1 2.2 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 EIW82657.1 - 3.2e-20 71.6 0.1 7.6e-20 70.3 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 EIW82657.1 - 5.2e-12 45.8 0.3 5.2e-12 45.8 0.2 2.3 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIW82657.1 - 1.7e-09 37.7 0.0 4.3e-09 36.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 GATase PF00117.23 EIW82658.1 - 7.9e-10 38.4 0.0 3.3e-09 36.4 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I HTS PF04204.11 EIW82658.1 - 0.011 14.4 0.0 0.019 13.7 0.0 1.3 1 0 0 1 1 1 0 Homoserine O-succinyltransferase GATase PF00117.23 EIW82659.1 - 8e-05 22.1 0.0 0.0019 17.6 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Asp PF00026.18 EIW82660.1 - 1.9e-76 257.3 4.8 2.3e-76 257.0 3.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW82660.1 - 4.4e-08 33.2 5.0 4e-06 26.8 2.4 3.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal nec1 PF10379.4 EIW82660.1 - 0.019 14.2 0.1 0.036 13.3 0.1 1.4 1 0 0 1 1 1 0 Virulence protein nec1 UPF0020 PF01170.13 EIW82661.1 - 2e-14 53.5 0.0 3.6e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EIW82661.1 - 4.7e-14 52.4 0.0 8.8e-14 51.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 EIW82661.1 - 5.6e-06 26.0 0.0 0.083 12.3 0.0 2.6 2 1 0 2 2 2 2 DNA methylase N6_Mtase PF02384.11 EIW82661.1 - 0.0096 15.0 0.0 0.059 12.4 0.0 2.2 2 1 0 2 2 2 1 N-6 DNA Methylase Methyltransf_15 PF09445.5 EIW82661.1 - 0.019 14.5 0.0 0.04 13.4 0.0 1.5 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase MFS_1 PF07690.11 EIW82662.1 - 3.9e-13 48.8 37.0 5.7e-13 48.2 25.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily zf-U1 PF06220.7 EIW82663.1 - 1.1e-10 40.8 1.3 1.7e-10 40.2 0.9 1.3 1 0 0 1 1 1 1 U1 zinc finger UspB PF10625.4 EIW82664.1 - 0.0015 18.3 0.1 0.0036 17.0 0.0 1.6 1 1 0 1 1 1 1 Universal stress protein B (UspB) HMG_box PF00505.14 EIW82666.1 - 6.7e-06 26.2 2.1 3.1e-05 24.1 0.3 2.3 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIW82666.1 - 0.016 15.5 0.2 0.016 15.5 0.2 2.5 3 0 0 3 3 3 0 HMG-box domain PCI_Csn8 PF10075.4 EIW82667.1 - 0.17 11.6 0.2 0.56 9.9 0.0 1.8 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 NP1-WLL PF11733.3 EIW82669.1 - 0.0031 17.7 4.0 0.0089 16.2 2.8 1.8 1 0 0 1 1 1 1 Non-capsid protein NP1 COG5 PF10392.4 EIW82672.1 - 5.5e-31 107.2 0.1 4.2e-30 104.3 0.0 2.5 3 0 0 3 3 3 1 Golgi transport complex subunit 5 Vps51 PF08700.6 EIW82672.1 - 1.6e-05 24.6 2.0 0.00024 20.8 0.0 3.6 3 1 0 3 3 3 1 Vps51/Vps67 Dor1 PF04124.7 EIW82672.1 - 0.015 13.8 3.5 0.05 12.0 0.4 2.4 2 0 0 2 2 2 0 Dor1-like family Syntaxin-6_N PF09177.6 EIW82672.1 - 0.016 15.5 0.8 1.6 9.2 0.1 4.0 3 1 1 4 4 4 0 Syntaxin 6, N-terminal IncA PF04156.9 EIW82672.1 - 0.052 13.1 2.2 0.051 13.1 0.4 1.8 2 0 0 2 2 2 0 IncA protein SWIM PF04434.12 EIW82673.1 - 4.9e-07 29.1 0.8 9.5e-07 28.1 0.5 1.5 1 0 0 1 1 1 1 SWIM zinc finger TcdA_TcdB_pore PF12920.2 EIW82673.1 - 0.1 10.5 0.0 0.14 10.0 0.0 1.2 1 0 0 1 1 1 0 TcdA/TcdB pore forming domain DUF3317 PF11779.3 EIW82674.1 - 1.7e-07 30.5 3.9 2.7e-07 29.9 2.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Tim17 PF02466.14 EIW82676.1 - 1.7e-30 105.6 6.8 2.1e-30 105.3 4.7 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family zf-4CXXC_R1 PF10497.4 EIW82677.1 - 1.3e-12 47.7 12.0 1.4e-11 44.4 8.3 2.3 1 1 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 DUF1690 PF07956.6 EIW82680.1 - 0.076 12.9 0.5 0.15 12.0 0.3 1.5 1 1 0 1 1 1 0 Protein of Unknown function (DUF1690) zf-U11-48K PF05253.7 EIW82680.1 - 0.078 12.7 0.2 0.8 9.4 0.0 2.2 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger adh_short PF00106.20 EIW82681.1 - 3e-19 69.5 0.4 3e-19 69.5 0.3 1.5 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW82681.1 - 4.5e-14 52.8 0.0 1.1e-13 51.5 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW82681.1 - 4.2e-07 29.8 0.2 3.3e-06 26.8 0.1 2.1 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIW82681.1 - 0.00043 20.3 0.0 0.00079 19.4 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW82681.1 - 0.0012 18.3 0.0 0.0028 17.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EIW82681.1 - 0.046 13.5 0.1 0.094 12.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Pex24p PF06398.6 EIW82683.1 - 9.6e-27 93.7 6.7 5.6e-26 91.1 4.7 2.1 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin Mannosyl_trans2 PF04188.8 EIW82684.1 - 1.8e-62 211.7 7.9 2.2e-62 211.4 5.5 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) p450 PF00067.17 EIW82685.1 - 4.8e-54 183.6 0.0 6.3e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Daxx PF03344.10 EIW82689.1 - 0.04 12.4 19.8 0.082 11.3 13.7 1.6 1 0 0 1 1 1 0 Daxx Family TFIIA PF03153.8 EIW82689.1 - 0.89 9.3 22.8 0.051 13.4 11.9 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit adh_short PF00106.20 EIW82690.1 - 5.3e-15 55.7 1.2 9.7e-10 38.6 0.0 2.2 1 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EIW82690.1 - 6.5e-12 45.7 0.1 6.2e-07 29.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW82690.1 - 2.1e-07 30.8 0.6 0.00071 19.2 0.0 2.2 1 1 0 2 2 2 2 KR domain NAD_binding_10 PF13460.1 EIW82690.1 - 2.4e-05 24.4 0.4 5.8e-05 23.1 0.3 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW82690.1 - 0.00079 18.9 0.5 0.011 15.1 0.3 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family LTP_2 PF14368.1 EIW82691.1 - 0.11 12.6 1.2 0.19 11.8 0.1 1.9 1 1 1 2 2 2 0 Probable lipid transfer Pheromone PF08015.6 EIW82691.1 - 0.15 12.8 0.5 0.15 12.8 0.4 2.2 1 1 2 3 3 3 0 Fungal mating-type pheromone adh_short PF00106.20 EIW82693.1 - 4.5e-23 81.9 0.6 5.6e-23 81.6 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW82693.1 - 1.1e-15 58.0 0.0 2e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW82693.1 - 6.1e-11 42.3 0.1 9.5e-11 41.6 0.1 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIW82693.1 - 1.5e-06 28.3 0.1 2.9e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW82693.1 - 2e-05 24.1 0.1 0.00011 21.6 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIW82693.1 - 0.002 17.1 0.0 0.003 16.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain TOBE PF03459.12 EIW82693.1 - 0.031 14.3 0.1 0.11 12.5 0.0 2.0 2 0 0 2 2 2 0 TOBE domain NmrA PF05368.8 EIW82693.1 - 0.076 12.2 0.1 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family SKG6 PF08693.5 EIW82694.1 - 0.0033 16.6 3.9 0.007 15.6 2.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.15 EIW82694.1 - 0.02 14.5 0.2 0.032 13.8 0.2 1.3 1 0 0 1 1 1 0 Syndecan domain FGGY_C PF02782.11 EIW82694.1 - 0.066 12.8 0.0 0.087 12.4 0.0 1.1 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain Glycophorin_A PF01102.13 EIW82694.1 - 0.078 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Glycophorin A ABC_tran PF00005.22 EIW82695.1 - 8.5e-51 171.8 0.0 1.3e-29 103.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIW82695.1 - 8.4e-45 153.3 20.4 2.7e-21 76.2 3.3 3.4 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 EIW82695.1 - 2.4e-09 37.6 0.0 0.0091 15.9 0.0 4.3 2 2 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EIW82695.1 - 1e-07 31.5 0.2 0.0015 17.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EIW82695.1 - 1.5e-07 30.8 1.3 0.0023 17.2 0.1 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain T2SE PF00437.15 EIW82695.1 - 5.7e-07 28.7 0.0 0.013 14.3 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 EIW82695.1 - 1.2e-05 24.7 0.2 0.096 12.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EIW82695.1 - 3.5e-05 24.2 0.0 0.013 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIW82695.1 - 8.7e-05 22.5 0.2 0.53 10.2 0.2 3.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EIW82695.1 - 0.0017 18.5 0.7 25 5.0 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 EIW82695.1 - 0.0024 17.6 0.1 0.29 10.9 0.0 3.0 2 0 0 2 2 2 1 Part of AAA domain Arch_ATPase PF01637.13 EIW82695.1 - 0.003 17.2 0.0 0.069 12.8 0.0 2.5 3 0 0 3 3 3 1 Archaeal ATPase AAA_10 PF12846.2 EIW82695.1 - 0.0054 16.2 0.7 1.1 8.6 0.1 2.8 2 0 0 2 2 2 1 AAA-like domain DUF87 PF01935.12 EIW82695.1 - 0.0056 16.5 0.1 0.019 14.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_17 PF13207.1 EIW82695.1 - 0.022 15.5 0.1 13 6.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EIW82695.1 - 0.023 14.6 0.0 2 8.4 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.1 EIW82695.1 - 0.023 14.9 0.1 9.9 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EIW82695.1 - 0.028 13.9 0.2 3.2 7.1 0.0 2.7 3 0 0 3 3 3 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EIW82695.1 - 0.03 13.3 0.0 2.8 6.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin MobB PF03205.9 EIW82695.1 - 0.038 13.7 0.1 4.4 7.0 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EIW82695.1 - 0.047 13.4 1.3 2 8.1 0.0 3.5 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EIW82695.1 - 0.063 12.4 0.0 5.3 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NACHT PF05729.7 EIW82695.1 - 0.066 12.8 0.4 5.2 6.6 0.0 2.7 2 0 0 2 2 2 0 NACHT domain Miro PF08477.8 EIW82695.1 - 0.11 13.0 0.1 15 6.0 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Asparaginase_2 PF01112.13 EIW82697.1 - 1.7e-55 187.9 0.0 2.9e-40 137.9 0.0 2.4 2 1 0 2 2 2 2 Asparaginase G_glu_transpept PF01019.16 EIW82697.1 - 0.0086 14.6 0.9 0.021 13.3 0.1 1.9 2 0 0 2 2 2 1 Gamma-glutamyltranspeptidase SKG6 PF08693.5 EIW82698.1 - 0.00057 19.1 0.9 0.0013 18.0 0.6 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1049 PF06305.6 EIW82698.1 - 0.051 13.0 0.1 0.081 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Herpes_gE PF02480.11 EIW82698.1 - 0.084 11.1 0.0 0.12 10.6 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF605 PF04652.11 EIW82698.1 - 0.46 9.8 3.1 0.47 9.7 0.6 1.9 2 0 0 2 2 2 0 Vta1 like Dynamitin PF04912.9 EIW82699.1 - 1.1e-22 80.3 1.5 1.2e-11 44.0 0.0 3.3 4 0 0 4 4 4 3 Dynamitin Rubella_Capsid PF05750.6 EIW82699.1 - 0.011 15.1 5.6 0.011 15.1 3.9 2.6 2 1 1 3 3 3 0 Rubella capsid protein DUF1192 PF06698.6 EIW82699.1 - 0.086 12.6 7.5 2.7 7.8 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Allexi_40kDa PF05549.6 EIW82699.1 - 0.18 11.0 0.3 9.7 5.3 0.1 2.2 1 1 1 2 2 2 0 Allexivirus 40kDa protein IncA PF04156.9 EIW82699.1 - 0.21 11.1 3.5 1.2 8.6 0.0 2.7 3 0 0 3 3 3 0 IncA protein Con-6 PF10346.4 EIW82700.1 - 8.4e-39 130.6 6.5 2.1e-12 46.2 0.1 3.1 3 0 0 3 3 3 3 Conidiation protein 6 SpoIIIAH PF12685.2 EIW82700.1 - 0.0048 16.4 0.2 0.45 9.9 0.0 2.7 2 1 0 3 3 3 1 SpoIIIAH-like protein DUF3812 PF12757.2 EIW82700.1 - 0.27 11.2 2.6 0.42 10.5 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3812) DUF3359 PF11839.3 EIW82700.1 - 1.7 9.0 8.1 1.3 9.4 0.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3359) SNF2_N PF00176.18 EIW82701.1 - 1.3e-68 231.0 0.0 2.1e-68 230.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EIW82701.1 - 6.7e-16 58.1 0.0 1.6e-15 56.9 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain zf-PARP PF00645.13 EIW82701.1 - 1.3e-15 57.4 0.0 3e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Helicase_C PF00271.26 EIW82701.1 - 6.8e-09 35.4 0.0 0.0003 20.5 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EIW82701.1 - 1.8e-08 33.8 6.8 3.8e-08 32.8 4.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW82701.1 - 5.1e-08 32.8 6.1 1.2e-07 31.6 4.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW82701.1 - 4e-07 29.7 4.9 8.2e-07 28.7 3.4 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EIW82701.1 - 0.00011 21.7 7.0 0.00022 20.8 4.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW82701.1 - 0.00014 21.5 7.6 0.00025 20.6 5.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EIW82701.1 - 0.0011 18.7 5.6 0.0023 17.7 3.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EIW82701.1 - 0.0019 18.2 2.5 0.0045 17.0 1.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger ResIII PF04851.10 EIW82701.1 - 0.014 15.1 1.9 0.017 14.9 0.0 2.1 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit zf-RING_4 PF14570.1 EIW82701.1 - 1.3 8.6 6.5 2.9 7.5 4.5 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Nse4_C PF08743.5 EIW82702.1 - 1.2e-26 92.5 0.7 2.5e-26 91.5 0.0 1.8 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EIW82702.1 - 1.6e-16 59.8 1.1 7.3e-16 57.7 1.0 1.9 2 0 0 2 2 2 1 Binding domain of Nse4/EID3 to Nse3-MAGE ABC_tran PF00005.22 EIW82703.1 - 2.4e-50 170.3 0.0 1.5e-29 103.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIW82703.1 - 2.9e-46 158.0 21.7 1e-22 80.8 4.4 3.6 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_21 PF13304.1 EIW82703.1 - 4.2e-09 36.7 0.1 0.062 13.2 0.0 4.2 3 1 0 3 3 3 3 AAA domain SMC_N PF02463.14 EIW82703.1 - 1.8e-07 30.6 0.0 0.0054 15.9 0.1 3.7 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EIW82703.1 - 2.1e-07 30.5 0.1 0.0042 16.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EIW82703.1 - 5.1e-07 28.8 0.0 0.015 14.2 0.0 2.6 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_29 PF13555.1 EIW82703.1 - 1.2e-05 24.7 0.1 0.097 12.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EIW82703.1 - 2.6e-05 24.3 0.6 0.15 12.0 0.2 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 EIW82703.1 - 4e-05 24.0 0.2 0.02 15.2 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EIW82703.1 - 0.0022 17.7 0.4 0.23 11.2 0.1 3.1 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EIW82703.1 - 0.0027 17.8 0.7 20 5.3 0.0 3.5 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.12 EIW82703.1 - 0.0077 16.0 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF87 MMR_HSR1 PF01926.18 EIW82703.1 - 0.022 14.6 0.3 2 8.4 0.0 2.9 3 0 0 3 3 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 EIW82703.1 - 0.024 14.0 3.0 1.2 8.5 0.1 2.6 2 1 0 2 2 2 0 AAA-like domain Zeta_toxin PF06414.7 EIW82703.1 - 0.024 13.7 0.0 2.3 7.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.1 EIW82703.1 - 0.026 14.8 0.1 10 6.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EIW82703.1 - 0.033 13.9 0.1 0.77 9.4 0.0 2.6 2 1 0 2 2 2 0 Archaeal ATPase FtsK_SpoIIIE PF01580.13 EIW82703.1 - 0.035 13.5 0.0 3.4 7.1 0.0 2.7 3 0 0 3 3 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EIW82703.1 - 0.035 14.9 0.1 14 6.5 0.1 2.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EIW82703.1 - 0.044 13.4 0.1 4.4 7.0 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EIW82703.1 - 0.1 11.7 0.0 9.4 5.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Miro PF08477.8 EIW82703.1 - 0.12 12.9 0.1 16 5.9 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein NACHT PF05729.7 EIW82703.1 - 0.37 10.4 3.5 5.2 6.6 0.0 2.8 3 0 0 3 3 3 0 NACHT domain AAA_5 PF07728.9 EIW82703.1 - 1.2 8.8 4.1 2.1 8.0 0.0 3.1 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) APH PF01636.18 EIW82704.1 - 5.7e-15 55.6 0.0 2.2e-14 53.7 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EIW82704.1 - 0.00014 20.6 0.0 0.061 11.9 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 EIW82704.1 - 0.016 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase adh_short PF00106.20 EIW82705.1 - 8.4e-18 64.8 0.9 1.2e-17 64.2 0.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW82705.1 - 2e-07 31.0 0.0 3.3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW82705.1 - 2.7e-06 27.1 0.2 4.3e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIW82705.1 - 0.00069 19.6 0.1 0.00097 19.1 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding TPP1 PF10341.4 EIW82706.1 - 2.9e-07 30.4 0.0 6.1e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Shelterin complex subunit, TPP1/ACD F-box-like PF12937.2 EIW82707.1 - 2.9e-09 36.5 0.8 2.7e-08 33.4 0.3 2.7 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 EIW82707.1 - 0.0091 15.6 1.6 0.11 12.1 1.1 2.8 1 1 0 1 1 1 1 F-box domain Linocin_M18 PF04454.7 EIW82709.1 - 0.078 11.8 0.0 0.083 11.7 0.0 1.0 1 0 0 1 1 1 0 Encapsulating protein for peroxidase Sugar_tr PF00083.19 EIW82710.1 - 4.4e-78 262.8 29.3 5.1e-78 262.6 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW82710.1 - 3.5e-21 75.3 41.5 1.6e-12 46.8 8.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.2 EIW82711.1 - 6.8e-05 22.5 0.7 0.00021 20.9 0.5 1.9 1 1 0 1 1 1 1 F-box-like ABC_tran PF00005.22 EIW82712.1 - 1.1e-50 171.4 0.0 2.7e-29 102.2 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIW82712.1 - 1.6e-42 145.8 21.4 2.6e-22 79.5 4.5 2.8 2 2 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EIW82712.1 - 1.3e-10 41.7 0.0 0.0072 16.3 0.0 4.1 2 2 0 3 3 3 3 AAA domain AAA_25 PF13481.1 EIW82712.1 - 3e-08 33.3 0.0 0.0014 18.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EIW82712.1 - 8.8e-08 31.6 0.0 0.00071 18.8 0.0 3.4 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain T2SE PF00437.15 EIW82712.1 - 1.6e-06 27.2 0.1 0.019 13.8 0.0 2.5 3 0 0 3 3 2 2 Type II/IV secretion system protein AAA_23 PF13476.1 EIW82712.1 - 5.9e-06 26.7 0.1 0.00061 20.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EIW82712.1 - 1.6e-05 24.3 0.1 0.086 12.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EIW82712.1 - 0.00044 20.3 0.6 9.4 6.3 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 EIW82712.1 - 0.00052 20.0 4.1 0.34 10.8 0.0 3.5 3 1 0 3 3 2 2 AAA ATPase domain AAA_19 PF13245.1 EIW82712.1 - 0.00083 19.0 0.2 0.29 10.9 0.0 3.4 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 EIW82712.1 - 0.009 16.3 0.1 3.6 7.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.13 EIW82712.1 - 0.009 15.5 0.0 5.7 6.3 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 EIW82712.1 - 0.015 15.0 0.0 0.15 11.7 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase AAA_10 PF12846.2 EIW82712.1 - 0.022 14.2 0.0 5.8 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 EIW82712.1 - 0.032 15.0 0.1 15 6.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EIW82712.1 - 0.034 13.9 0.0 0.08 12.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF258 PF03193.11 EIW82712.1 - 0.038 13.1 0.0 7.2 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EIW82712.1 - 0.041 13.8 0.1 3.8 7.4 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase MobB PF03205.9 EIW82712.1 - 0.041 13.5 0.0 9 5.9 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EIW82712.1 - 0.067 13.6 0.1 12 6.4 0.0 2.9 3 0 0 3 3 2 0 Miro-like protein AAA PF00004.24 EIW82712.1 - 0.083 13.0 0.8 24 5.1 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EIW82712.1 - 0.096 12.5 0.2 10 5.9 0.0 3.0 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EIW82712.1 - 0.13 12.0 0.1 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Dynamin family AAA_5 PF07728.9 EIW82712.1 - 0.14 11.8 2.1 1.1 8.9 0.0 3.2 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) ABC_ATPase PF09818.4 EIW82712.1 - 0.16 10.5 0.4 1.2 7.5 0.0 2.2 2 0 0 2 2 2 0 Predicted ATPase of the ABC class AAA_14 PF13173.1 EIW82712.1 - 0.23 11.3 0.1 3.2 7.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain Cauli_VI PF01693.11 EIW82714.1 - 1.2e-07 31.6 0.4 1.9e-07 30.9 0.3 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin PSK_trans_fac PF07704.6 EIW82716.1 - 0.04 14.6 0.5 0.04 14.6 0.3 3.3 2 1 1 3 3 3 0 Rv0623-like transcription factor Metallophos PF00149.23 EIW82717.1 - 1.1e-11 44.4 0.1 2.1e-11 43.5 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIW82717.1 - 0.0027 17.5 0.0 0.0052 16.6 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FAM176 PF14851.1 EIW82718.1 - 1.6 8.4 5.4 7.3 6.2 3.8 2.1 1 0 0 1 1 1 0 FAM176 family IFT57 PF10498.4 EIW82718.1 - 7.4 5.2 7.4 8.1 5.0 4.3 1.6 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 DUF572 PF04502.8 EIW82719.1 - 1.5 7.9 4.8 2 7.5 3.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Ribosomal_S8e PF01201.17 EIW82721.1 - 4.1e-49 166.0 1.0 5.6e-49 165.6 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e NADH_B2 PF14813.1 EIW82722.1 - 0.0095 15.5 0.1 0.01 15.4 0.1 1.2 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 Cpn60_TCP1 PF00118.19 EIW82723.1 - 4.1e-149 497.3 0.0 5e-149 497.0 0.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family adh_short_C2 PF13561.1 EIW82725.1 - 7.1e-27 94.7 0.1 8.6e-27 94.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIW82725.1 - 1.9e-26 92.9 0.1 2.5e-26 92.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW82725.1 - 2.5e-12 46.8 0.7 2.7e-11 43.4 0.5 2.0 1 1 0 1 1 1 1 KR domain Methyltransf_25 PF13649.1 EIW82725.1 - 0.0015 18.8 0.0 0.0031 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MFS_1 PF07690.11 EIW82726.1 - 1e-17 63.9 65.0 4.2e-16 58.6 22.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIW82726.1 - 1.7e-07 30.0 5.1 1.7e-07 30.0 3.5 2.9 2 1 1 3 3 3 1 MFS/sugar transport protein DUF3566 PF12089.3 EIW82726.1 - 1.7 8.6 6.3 11 6.0 0.0 2.8 3 0 0 3 3 3 0 Transmembrane domain of unknown function (DUF3566) Sugar_tr PF00083.19 EIW82727.1 - 4.2e-78 262.9 27.5 4.8e-78 262.7 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW82727.1 - 4.4e-25 88.1 35.4 4.9e-14 51.8 8.5 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW82728.1 - 8.1e-69 232.3 29.1 9.5e-69 232.1 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW82728.1 - 2.3e-18 66.0 41.6 1.9e-11 43.3 9.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Thaumatin PF00314.12 EIW82729.1 - 5.9e-17 61.8 5.9 6.7e-17 61.6 4.1 1.1 1 0 0 1 1 1 1 Thaumatin family BSD PF03909.12 EIW82730.1 - 1.2e-18 66.5 0.0 3.1e-12 46.0 0.0 3.0 3 0 0 3 3 3 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EIW82730.1 - 6e-09 35.4 0.0 1.3e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain COX16 PF14138.1 EIW82730.1 - 0.07 13.3 0.0 0.22 11.6 0.0 1.9 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 Put_Phosphatase PF06888.7 EIW82731.1 - 2.2e-50 171.0 0.0 2.5e-50 170.8 0.0 1.0 1 0 0 1 1 1 1 Putative Phosphatase HAD_2 PF13419.1 EIW82731.1 - 2.3e-05 24.6 0.0 4.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.2 EIW82731.1 - 0.0049 17.0 0.1 0.011 15.8 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase P63C PF10546.4 EIW82731.1 - 0.075 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 P63C domain F-box PF00646.28 EIW82732.1 - 2e-05 24.1 0.2 4.6e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW82732.1 - 0.00041 20.0 0.7 0.00074 19.1 0.5 1.4 1 0 0 1 1 1 1 F-box-like Pkinase PF00069.20 EIW82734.1 - 2.7e-54 184.0 0.0 7.6e-54 182.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW82734.1 - 2.3e-22 79.2 0.0 3.4e-22 78.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW82734.1 - 3.4e-05 23.6 0.0 6.5e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIW82734.1 - 0.0013 18.1 0.4 0.0031 16.8 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Choline_kinase PF01633.15 EIW82734.1 - 0.035 13.6 0.3 0.08 12.4 0.2 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase zf-GRF PF06839.7 EIW82736.1 - 1.4e-09 37.7 0.3 2.4e-09 36.9 0.2 1.4 1 0 0 1 1 1 1 GRF zinc finger PsbW PF07123.7 EIW82736.1 - 0.11 12.5 3.3 0.36 10.9 2.3 1.8 1 0 0 1 1 1 0 Photosystem II reaction centre W protein (PsbW) TSC22 PF01166.13 EIW82736.1 - 0.18 11.7 0.3 15 5.6 0.0 2.4 2 0 0 2 2 2 0 TSC-22/dip/bun family ADIP PF11559.3 EIW82736.1 - 0.62 9.9 2.3 0.69 9.8 0.2 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding LAG1-DNAbind PF09271.6 EIW82739.1 - 6.3e-34 117.4 0.0 1.1e-33 116.6 0.0 1.4 1 0 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 EIW82739.1 - 2.3e-24 85.9 0.0 4.1e-19 68.8 0.0 3.0 1 1 1 2 2 2 2 Beta-trefoil DNA-binding domain MOZ_SAS PF01853.13 EIW82741.1 - 8.5e-85 282.7 0.5 1.2e-84 282.2 0.3 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EIW82741.1 - 1e-15 57.1 0.1 2.7e-15 55.8 0.1 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain HTH_11 PF08279.7 EIW82741.1 - 0.011 15.3 0.1 0.022 14.4 0.1 1.4 1 0 0 1 1 1 0 HTH domain HTH_Mga PF08280.6 EIW82741.1 - 0.014 15.1 0.4 0.028 14.1 0.3 1.4 1 0 0 1 1 1 0 M protein trans-acting positive regulator (MGA) HTH domain Acetyltransf_1 PF00583.19 EIW82741.1 - 0.088 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family CDC27 PF09507.5 EIW82741.1 - 0.58 9.3 19.6 1.1 8.4 13.6 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Methyltransf_26 PF13659.1 EIW82744.1 - 1.5e-09 37.9 0.0 2.3e-08 34.0 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW82744.1 - 0.015 14.8 0.0 0.044 13.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain zf-CCHC PF00098.18 EIW82745.1 - 1.4e-06 27.9 0.8 2.9e-06 26.9 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Retrotrans_gag PF03732.12 EIW82745.1 - 2.3e-06 27.5 0.8 5.5e-06 26.3 0.4 1.7 2 0 0 2 2 2 1 Retrotransposon gag protein zf-CCHC_2 PF13696.1 EIW82745.1 - 0.057 12.9 0.6 0.13 11.8 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Zn_clus PF00172.13 EIW82746.1 - 8.7e-05 22.3 11.0 0.00014 21.6 7.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EIW82746.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 PAS fold FeThRed_B PF02943.10 EIW82747.1 - 0.079 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase catalytic beta chain TPR_11 PF13414.1 EIW82752.1 - 2.9e-19 68.4 11.5 5e-11 42.0 0.9 4.4 2 2 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 EIW82752.1 - 2.9e-13 48.7 7.6 0.00053 19.4 0.9 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIW82752.1 - 9.5e-13 47.0 16.1 0.0074 16.1 1.1 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.1 EIW82752.1 - 9.5e-12 45.0 13.7 1.3e-06 28.6 1.1 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIW82752.1 - 6.6e-11 41.5 12.6 0.0061 16.6 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EIW82752.1 - 8.4e-10 38.4 12.8 1.5e-06 28.0 0.9 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIW82752.1 - 3.7e-09 36.3 30.8 0.001 19.4 0.4 7.3 5 2 3 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EIW82752.1 - 2.6e-08 34.2 24.8 4.2e-06 27.2 1.9 6.5 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIW82752.1 - 3.5e-06 26.3 4.1 0.012 15.3 0.7 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_20 PF14561.1 EIW82752.1 - 1.7e-05 24.8 11.6 0.1 12.6 0.5 5.3 2 2 3 5 5 5 3 Tetratricopeptide repeat Apc3 PF12895.2 EIW82752.1 - 0.00025 21.0 4.5 0.0022 18.0 1.4 3.3 2 2 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EIW82752.1 - 0.0037 16.9 5.5 11 6.1 0.0 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 EIW82752.1 - 0.011 15.5 0.8 0.011 15.5 0.5 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.13 EIW82752.1 - 0.051 13.4 0.5 1.8 8.5 0.2 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_10 PF13374.1 EIW82752.1 - 0.25 11.3 17.3 3.6 7.6 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat Glyco_hydro_43 PF04616.9 EIW82753.1 - 3.3e-25 88.7 2.7 5.6e-24 84.7 0.3 2.6 2 1 0 2 2 2 1 Glycosyl hydrolases family 43 PRA1 PF03208.14 EIW82754.1 - 7.1e-39 132.6 0.8 7.8e-39 132.4 0.5 1.0 1 0 0 1 1 1 1 PRA1 family protein adh_short PF00106.20 EIW82757.1 - 1.1e-20 74.1 2.9 4.6e-20 72.1 2.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW82757.1 - 2.4e-20 73.3 0.1 3.7e-20 72.7 0.1 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW82757.1 - 7.4e-11 42.0 0.1 1.1e-10 41.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 EIW82757.1 - 0.045 13.5 0.1 0.11 12.3 0.1 1.7 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.16 EIW82757.1 - 0.14 11.5 0.1 0.62 9.4 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Got1 PF04178.7 EIW82759.1 - 9.5e-22 77.3 15.9 1.1e-21 77.1 11.0 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family DUF973 PF06157.6 EIW82759.1 - 0.24 10.3 10.2 0.3 10.0 6.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF973) DUF3185 PF11381.3 EIW82759.1 - 4.6 7.0 13.2 3.5 7.4 1.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3185) DUF2157 PF09925.4 EIW82759.1 - 9.7 5.7 9.5 18 4.9 6.6 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2157) adh_short PF00106.20 EIW82760.1 - 2.2e-30 105.7 0.6 3.3e-30 105.2 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW82760.1 - 8.5e-23 81.3 0.0 1.1e-22 81.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW82760.1 - 1.9e-13 50.4 0.6 3.4e-13 49.6 0.4 1.4 1 0 0 1 1 1 1 KR domain HHH_5 PF14520.1 EIW82760.1 - 0.075 13.2 0.0 0.37 11.0 0.0 2.3 2 1 0 2 2 2 0 Helix-hairpin-helix domain adh_short PF00106.20 EIW82761.1 - 4.4e-22 78.7 0.4 4.9e-22 78.6 0.3 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW82761.1 - 8.7e-10 38.5 0.2 1e-09 38.3 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIW82761.1 - 1.5e-08 34.7 0.0 1.7e-08 34.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HHH_5 PF14520.1 EIW82761.1 - 0.065 13.4 0.2 0.11 12.6 0.1 1.6 1 1 0 1 1 1 0 Helix-hairpin-helix domain Eno-Rase_NADH_b PF12242.3 EIW82761.1 - 0.12 12.1 1.5 0.33 10.7 0.3 2.1 2 1 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_4 PF07993.7 EIW82762.1 - 2.2e-39 134.8 0.0 3.2e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EIW82762.1 - 1.9e-36 125.3 0.2 4.6e-36 124.0 0.2 1.6 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EIW82762.1 - 3.8e-11 42.8 0.0 1.9e-10 40.5 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EIW82762.1 - 2.3e-08 34.1 0.0 6.4e-08 32.7 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EIW82762.1 - 0.00023 21.1 1.0 0.004 17.1 0.7 2.5 1 1 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 EIW82762.1 - 0.078 13.2 0.0 0.22 11.8 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain IF-2B PF01008.12 EIW82764.1 - 5.6e-60 202.7 0.0 6.6e-60 202.4 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family Abhydrolase_3 PF07859.8 EIW82765.1 - 3.7e-28 98.5 0.0 1.4e-19 70.5 0.0 2.7 2 0 0 2 2 2 2 alpha/beta hydrolase fold Gcd10p PF04189.8 EIW82765.1 - 0.0052 15.9 0.0 0.0097 15.0 0.0 1.3 1 0 0 1 1 1 1 Gcd10p family DUF2424 PF10340.4 EIW82765.1 - 0.081 11.5 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Aldo_ket_red PF00248.16 EIW82766.1 - 4.8e-17 61.6 0.0 8e-10 38.0 0.0 3.0 1 1 1 2 2 2 2 Aldo/keto reductase family DUF4154 PF13689.1 EIW82767.1 - 0.039 13.5 0.1 0.069 12.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4154) adh_short PF00106.20 EIW82768.1 - 4e-28 98.4 2.4 5.4e-28 98.0 1.7 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW82768.1 - 2.3e-25 89.7 0.1 2.7e-25 89.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW82768.1 - 1.3e-11 44.5 1.7 1.9e-11 43.9 1.2 1.3 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 EIW82768.1 - 0.052 13.3 0.1 0.12 12.1 0.1 1.7 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Aldo_ket_red PF00248.16 EIW82770.1 - 2.1e-62 210.5 0.0 2.5e-62 210.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FAD_binding_3 PF01494.14 EIW82773.1 - 2.5e-23 82.7 0.0 3.7e-11 42.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EIW82773.1 - 0.00035 20.5 0.8 0.00072 19.5 0.5 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EIW82773.1 - 0.013 14.1 0.2 0.036 12.7 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase DAO PF01266.19 EIW82773.1 - 0.025 13.4 3.3 0.045 12.6 2.3 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW82773.1 - 0.07 13.5 1.6 0.17 12.3 0.7 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIW82773.1 - 0.089 12.5 0.3 0.29 10.8 0.2 1.9 1 0 0 1 1 1 0 FAD-NAD(P)-binding Ferritin_2 PF13668.1 EIW82775.1 - 4.8e-17 62.1 0.0 6.5e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain MFS_1 PF07690.11 EIW82776.1 - 1.9e-17 63.0 34.6 1.9e-17 63.0 24.0 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF1049 PF06305.6 EIW82776.1 - 8.7 5.9 7.4 1.2 8.7 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) TRAP_alpha PF03896.11 EIW82777.1 - 0.11 11.5 1.7 0.15 11.0 1.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Ferritin_2 PF13668.1 EIW82778.1 - 4.6e-17 62.2 0.0 6.3e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain WD40 PF00400.27 EIW82779.1 - 2.9e-63 207.6 24.2 5.9e-12 44.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EIW82779.1 - 1.4e-05 23.4 4.5 0.014 13.5 0.5 3.5 2 1 1 3 3 3 2 Nucleoporin Nup120/160 DUF1513 PF07433.6 EIW82779.1 - 0.0014 17.5 0.0 0.12 11.2 0.0 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.11 EIW82779.1 - 0.004 15.5 0.0 0.44 8.7 0.1 2.4 2 1 0 2 2 2 2 Cytochrome D1 heme domain PD40 PF07676.7 EIW82779.1 - 0.032 13.9 2.0 15 5.3 0.0 4.2 6 0 0 6 6 6 0 WD40-like Beta Propeller Repeat DUF1416 PF07210.7 EIW82779.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) GFA PF04828.9 EIW82780.1 - 8.5e-27 92.9 2.0 1.2e-26 92.4 1.4 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Auto_anti-p27 PF06677.7 EIW82780.1 - 0.0012 18.5 0.2 0.0012 18.5 0.1 1.9 2 0 0 2 2 2 1 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Rpr2 PF04032.11 EIW82780.1 - 0.04 13.8 0.0 0.04 13.8 0.0 2.1 2 1 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF2757 PF10955.3 EIW82780.1 - 0.051 13.7 0.1 0.084 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2757) zf-ribbon_3 PF13248.1 EIW82780.1 - 0.37 10.0 0.1 0.37 10.0 0.1 2.4 3 0 0 3 3 3 0 zinc-ribbon domain Nudix_N_2 PF14803.1 EIW82780.1 - 0.63 9.7 0.1 0.63 9.7 0.1 3.2 3 0 0 3 3 3 0 Nudix N-terminal NOB1_Zn_bind PF08772.6 EIW82780.1 - 2.9 7.7 6.4 0.23 11.2 0.6 2.1 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Phage_holin_1 PF04531.8 EIW82781.1 - 2.9 8.0 8.1 0.27 11.3 1.2 2.5 2 1 0 2 2 2 0 Bacteriophage holin IU_nuc_hydro PF01156.14 EIW82782.1 - 1.2e-47 162.7 0.0 1.6e-47 162.2 0.0 1.2 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase FAD_binding_3 PF01494.14 EIW82783.1 - 1.8e-21 76.5 0.1 1.6e-20 73.4 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIW82783.1 - 0.00015 21.7 0.3 0.00044 20.2 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EIW82783.1 - 0.016 14.0 0.0 0.023 13.5 0.0 1.2 1 0 0 1 1 1 0 Squalene epoxidase DAO PF01266.19 EIW82783.1 - 0.023 13.6 0.1 0.045 12.6 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 EIW82783.1 - 0.081 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 EIW82784.1 - 5e-24 85.0 0.0 1.2e-11 44.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EIW82784.1 - 0.00024 21.0 1.2 0.0005 20.0 0.8 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EIW82784.1 - 0.0054 15.4 0.0 0.017 13.7 0.0 1.9 2 0 0 2 2 2 1 Tryptophan halogenase DAO PF01266.19 EIW82784.1 - 0.021 13.7 2.5 0.21 10.4 1.5 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 EIW82784.1 - 0.038 13.0 0.0 0.071 12.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EIW82784.1 - 0.092 12.5 0.3 0.21 11.3 0.2 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EIW82784.1 - 0.26 11.7 1.5 0.6 10.5 1.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ferritin_2 PF13668.1 EIW82785.1 - 1.5e-16 60.5 0.0 2.1e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain Adaptin_N PF01602.15 EIW82787.1 - 1.4e-14 53.3 0.1 1.9e-13 49.6 0.2 2.2 2 1 0 2 2 2 1 Adaptin N terminal region HEAT_2 PF13646.1 EIW82787.1 - 2.3e-06 27.7 2.2 0.0025 18.0 0.3 4.1 3 1 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EIW82787.1 - 7.2e-05 22.5 0.2 0.16 12.1 0.1 4.6 3 1 1 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EIW82787.1 - 0.048 14.1 7.2 0.073 13.5 0.9 4.0 3 1 1 4 4 4 0 HEAT-like repeat DUF3106 PF11304.3 EIW82787.1 - 0.17 12.3 2.5 6.9 7.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3106) RabGAP-TBC PF00566.13 EIW82788.1 - 2.9e-39 134.7 0.0 3.9e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain adh_short PF00106.20 EIW82789.1 - 1.4e-16 60.8 0.1 2.3e-16 60.1 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW82789.1 - 2.4e-08 33.8 0.2 3.9e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIW82789.1 - 1.1e-07 31.8 0.0 1.8e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EIW82789.1 - 0.015 14.7 0.1 0.029 13.7 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW82789.1 - 0.055 13.4 0.1 0.12 12.4 0.1 1.5 1 0 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 EIW82789.1 - 0.098 11.5 0.0 0.14 10.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein F-box PF00646.28 EIW82791.1 - 0.00045 19.8 0.1 0.0009 18.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW82791.1 - 0.0057 16.3 0.1 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like FAD_binding_3 PF01494.14 EIW82792.1 - 3.5e-29 101.9 0.0 4.5e-29 101.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIW82792.1 - 2.3e-08 33.3 0.3 0.00065 18.7 0.0 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW82792.1 - 2.3e-05 24.6 0.5 0.23 11.8 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW82792.1 - 0.00023 21.1 0.2 0.0017 18.3 0.0 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIW82792.1 - 0.00058 19.7 0.1 0.0012 18.7 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EIW82792.1 - 0.007 15.2 0.0 1 8.1 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase 3HCDH_N PF02737.13 EIW82792.1 - 0.01 15.4 0.0 0.024 14.3 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 EIW82792.1 - 0.012 14.2 0.4 0.21 10.1 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase Lycopene_cycl PF05834.7 EIW82792.1 - 0.035 13.0 0.0 2.5 6.9 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Glyco_hydro_30 PF02055.11 EIW82793.1 - 6.7e-21 74.0 2.4 1.5e-20 72.8 1.6 1.5 1 1 0 1 1 1 1 O-Glycosyl hydrolase family 30 FAD_binding_3 PF01494.14 EIW82794.1 - 9.7e-22 77.4 0.0 4.3e-11 42.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EIW82794.1 - 0.00027 20.8 0.7 0.00065 19.6 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EIW82794.1 - 0.013 14.2 0.2 0.032 12.8 0.0 1.8 2 1 0 2 2 2 0 Tryptophan halogenase DAO PF01266.19 EIW82794.1 - 0.023 13.5 2.2 0.049 12.5 1.5 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW82794.1 - 0.068 13.5 1.1 0.2 12.0 0.5 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW82794.1 - 0.081 12.7 0.0 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIW82794.1 - 0.12 12.0 0.4 0.42 10.3 0.2 2.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding Sugar_tr PF00083.19 EIW82795.1 - 0.066 11.7 10.3 0.9 8.0 5.7 2.4 1 1 0 1 1 1 0 Sugar (and other) transporter His_Phos_2 PF00328.17 EIW82796.1 - 2.7e-40 138.7 0.0 3.4e-40 138.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) GST_N_3 PF13417.1 EIW82797.1 - 1.1e-10 41.5 0.0 2e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW82797.1 - 3e-06 27.1 0.0 5.1e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW82797.1 - 0.0001 22.1 0.0 0.0002 21.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW82797.1 - 0.02 15.0 0.0 0.06 13.5 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIW82797.1 - 0.061 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Lactamase_B PF00753.22 EIW82799.1 - 6.8e-11 42.1 2.2 1.3e-10 41.3 1.5 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EIW82799.1 - 4.1e-06 26.4 0.1 6.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain PQQ_3 PF13570.1 EIW82799.1 - 0.017 15.4 0.2 0.051 13.8 0.1 1.8 1 0 0 1 1 1 0 PQQ-like domain DUF1517 PF07466.6 EIW82800.1 - 0.016 14.2 2.4 0.024 13.6 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Adeno_E1B_55K_N PF04623.7 EIW82800.1 - 8 7.0 10.9 3.5 8.1 3.5 2.3 2 0 0 2 2 2 0 Adenovirus E1B protein N-terminus E1-E2_ATPase PF00122.15 EIW82801.1 - 4.1e-29 101.2 0.0 8.7e-29 100.1 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EIW82801.1 - 5.7e-26 91.8 0.0 1e-25 91.0 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIW82801.1 - 5e-25 89.1 0.0 1.7e-23 84.1 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 EIW82801.1 - 2.1e-20 72.7 0.5 7.1e-20 71.0 0.0 2.1 2 0 0 2 2 2 1 P5-type ATPase cation transporter Cation_ATPase_C PF00689.16 EIW82801.1 - 4.4e-07 29.6 5.0 4.4e-07 29.6 3.5 1.8 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 EIW82801.1 - 7.9e-05 22.5 0.0 0.00019 21.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EIW82801.1 - 0.026 14.1 0.0 0.046 13.3 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PAP2 PF01569.16 EIW82802.1 - 1.4e-26 92.7 2.6 1.4e-26 92.7 1.8 1.7 2 0 0 2 2 2 1 PAP2 superfamily FUSC_2 PF13515.1 EIW82802.1 - 0.98 9.3 8.0 5.5 6.9 0.2 2.6 2 1 0 2 2 2 0 Fusaric acid resistance protein-like 2TM PF13239.1 EIW82802.1 - 2 8.5 5.0 7.5 6.6 0.4 2.9 3 0 0 3 3 3 0 2TM domain V-SNARE_C PF12352.3 EIW82803.1 - 1.1e-13 50.9 0.1 1.1e-13 50.9 0.1 2.6 2 1 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EIW82803.1 - 4.6e-06 26.2 1.1 4.2e-05 23.1 0.0 2.4 2 1 0 2 2 2 1 Sec20 AAA_27 PF13514.1 EIW82803.1 - 0.0019 15.9 7.4 0.098 10.3 3.7 2.3 1 1 1 2 2 2 2 AAA domain DivIVA PF05103.8 EIW82803.1 - 0.011 15.8 1.1 0.011 15.8 0.8 1.6 2 0 0 2 2 2 0 DivIVA protein Nup_retrotrp_bd PF10599.4 EIW82803.1 - 0.017 15.7 4.5 0.03 14.9 3.1 1.3 1 0 0 1 1 1 0 Retro-transposon transporting motif SPX PF03105.14 EIW82803.1 - 0.026 14.3 3.9 0.03 14.1 2.7 1.1 1 0 0 1 1 1 0 SPX domain DUF3513 PF12026.3 EIW82803.1 - 0.28 10.7 5.2 0.43 10.1 3.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3513) HALZ PF02183.13 EIW82803.1 - 0.47 10.2 2.9 1.8 8.3 0.6 2.8 2 1 0 2 2 2 0 Homeobox associated leucine zipper Plasmid_RAQPRD PF09686.5 EIW82803.1 - 3.5 7.7 6.9 2 8.5 2.5 2.2 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) Nop25 PF09805.4 EIW82804.1 - 1.5e-19 70.4 11.7 1.5e-19 70.4 8.1 2.6 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) FAM72 PF14976.1 EIW82805.1 - 2.5e-17 63.1 5.6 8.5e-16 58.1 3.9 2.1 1 1 0 1 1 1 1 FAM72 protein Serglycin PF04360.7 EIW82805.1 - 0.011 15.5 0.6 0.018 14.7 0.4 1.4 1 0 0 1 1 1 0 Serglycin Yippee-Mis18 PF03226.9 EIW82805.1 - 3.2 7.8 9.3 3.1 7.9 3.0 2.6 2 1 1 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Cellulase PF00150.13 EIW82806.1 - 7.2e-31 107.4 1.4 1.1e-30 106.8 1.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) SNase PF00565.12 EIW82808.1 - 2.5e-58 194.9 1.6 4.2e-19 68.8 0.0 6.2 5 1 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EIW82808.1 - 3.9e-22 78.3 0.0 6.9e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Tudor domain Yae1_N PF09811.4 EIW82809.1 - 0.00074 18.9 13.0 0.027 14.0 4.2 2.7 1 1 1 2 2 2 2 Essential protein Yae1, N terminal Fmp27_WPPW PF10359.4 EIW82809.1 - 0.0014 17.1 1.0 0.0019 16.7 0.7 1.2 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain TPR_MLP1_2 PF07926.7 EIW82809.1 - 0.032 13.9 2.9 0.081 12.6 0.2 2.4 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 EIW82809.1 - 0.071 12.9 10.4 0.038 13.8 5.2 1.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc24 PF08286.6 EIW82809.1 - 0.13 11.9 0.6 0.33 10.6 0.4 1.6 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DUF3373 PF11853.3 EIW82809.1 - 0.16 10.4 0.3 0.23 9.9 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) DUF904 PF06005.7 EIW82809.1 - 0.17 12.1 2.5 0.58 10.4 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF904) V_ATPase_I PF01496.14 EIW82809.1 - 0.25 9.1 4.4 0.33 8.7 3.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EzrA PF06160.7 EIW82809.1 - 0.63 8.1 7.3 0.84 7.7 5.1 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA APG6 PF04111.7 EIW82809.1 - 1.1 8.1 7.8 1.6 7.6 5.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 SlyX PF04102.7 EIW82809.1 - 3.3 8.1 9.7 4 7.8 0.8 3.3 2 1 1 3 3 3 0 SlyX Macoilin PF09726.4 EIW82809.1 - 4.9 5.3 18.6 8.1 4.5 12.9 1.3 1 1 0 1 1 1 0 Transmembrane protein DUF4200 PF13863.1 EIW82809.1 - 5 7.0 14.1 9 6.2 9.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DivIC PF04977.10 EIW82809.1 - 5.9 6.4 8.6 1.2 8.6 2.1 2.3 1 1 1 2 2 2 0 Septum formation initiator Amidohydro_2 PF04909.9 EIW82810.1 - 0.00034 20.2 1.1 0.00046 19.8 0.0 1.8 3 0 0 3 3 3 1 Amidohydrolase TPR_11 PF13414.1 EIW82812.1 - 8.8e-14 50.9 1.1 2.1e-13 49.7 0.3 1.9 1 1 0 1 1 1 1 TPR repeat F-box-like PF12937.2 EIW82812.1 - 1.1e-10 41.0 0.1 3.8e-10 39.3 0.0 2.0 1 0 0 1 1 1 1 F-box-like TPR_1 PF00515.23 EIW82812.1 - 4e-09 35.7 0.5 4.9e-05 22.7 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIW82812.1 - 8.7e-09 34.6 0.7 4e-05 23.1 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EIW82812.1 - 4e-05 23.0 1.0 0.072 12.9 0.0 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIW82812.1 - 4.3e-05 24.0 2.7 0.0076 16.9 0.3 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIW82812.1 - 0.00055 19.8 0.5 0.0017 18.2 0.2 1.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIW82812.1 - 0.0024 18.3 3.2 1.5 9.7 0.4 3.5 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIW82812.1 - 0.041 13.6 0.1 0.42 10.5 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat LRR_8 PF13855.1 EIW82812.1 - 0.17 11.6 7.5 34 4.3 0.0 4.8 5 0 0 5 5 5 0 Leucine rich repeat TPR_19 PF14559.1 EIW82812.1 - 0.32 11.3 4.2 0.1 12.9 0.5 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat LRR_7 PF13504.1 EIW82812.1 - 9 7.0 8.8 28 5.5 0.0 5.7 6 0 0 6 6 5 0 Leucine rich repeat MIF4G PF02854.14 EIW82813.1 - 1.1e-43 149.0 1.1 2.1e-25 89.3 0.0 3.0 4 0 0 4 4 4 2 MIF4G domain Upf2 PF04050.9 EIW82813.1 - 2.1e-27 95.9 5.0 2.1e-27 95.9 3.5 4.0 4 0 0 4 4 4 1 Up-frameshift suppressor 2 RRM_2 PF04059.7 EIW82814.1 - 3.3e-33 113.5 1.4 4.4e-33 113.1 1.0 1.2 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 EIW82814.1 - 1.8e-05 24.2 0.0 3.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW82814.1 - 0.0059 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 EIW82815.1 - 3.8e-20 71.9 50.4 4.3e-20 71.7 33.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_92 PF07971.7 EIW82816.1 - 2.9e-123 412.1 3.7 3.7e-123 411.8 2.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Pept_tRNA_hydro PF01195.14 EIW82817.1 - 2.5e-38 131.4 0.0 2.9e-38 131.2 0.0 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase ATP-cone PF03477.11 EIW82820.1 - 0.033 14.6 0.3 0.12 12.8 0.2 1.9 1 0 0 1 1 1 0 ATP cone domain DLH PF01738.13 EIW82821.1 - 3.9e-19 68.7 0.0 8.5e-19 67.7 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EIW82821.1 - 1.7e-07 31.1 0.0 2.8e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW82821.1 - 2.6e-05 24.2 0.0 0.0094 15.8 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW82821.1 - 0.00054 19.5 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2048 PF09752.4 EIW82821.1 - 0.081 11.7 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Spc7 PF08317.6 EIW82822.1 - 2.5e-06 26.4 14.8 2.5e-06 26.4 10.3 5.1 2 2 2 5 5 5 2 Spc7 kinetochore protein Baculo_PEP_C PF04513.7 EIW82822.1 - 4.4 7.1 23.3 0.031 14.1 3.3 4.3 2 2 1 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus PALP PF00291.20 EIW82824.1 - 7.5e-63 212.5 0.9 9.2e-63 212.2 0.6 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Arf PF00025.16 EIW82825.1 - 4.8e-77 257.1 0.0 5.4e-77 256.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EIW82825.1 - 2.8e-13 49.5 0.0 3.1e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EIW82825.1 - 6.5e-12 45.0 0.0 8e-12 44.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EIW82825.1 - 2.7e-11 42.8 1.4 1.7e-07 30.2 0.1 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EIW82825.1 - 8.4e-10 38.1 0.0 1e-09 37.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EIW82825.1 - 1.7e-07 31.7 0.0 2.3e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIW82825.1 - 0.00017 21.5 0.1 0.00042 20.2 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase L27 PF02828.11 EIW82825.1 - 0.012 15.2 1.6 0.082 12.6 0.1 2.2 2 0 0 2 2 2 0 L27 domain 6PF2K PF01591.13 EIW82825.1 - 0.02 13.9 0.1 0.029 13.4 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase LRR_4 PF12799.2 EIW82826.1 - 1.2e-13 50.3 19.4 1.3e-06 27.8 2.9 4.3 4 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW82826.1 - 2.4e-12 46.4 15.1 8.8e-09 34.9 5.1 3.7 3 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EIW82826.1 - 6.1e-07 28.6 16.3 0.2 11.8 0.1 6.7 4 2 2 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EIW82826.1 - 0.18 12.1 14.9 1.4 9.4 0.4 5.2 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 EIW82826.1 - 0.44 10.7 17.3 3.4 8.0 0.5 5.7 3 1 3 6 6 6 0 Leucine Rich repeat LRR_9 PF14580.1 EIW82826.1 - 0.97 8.9 2.5 2.8 7.4 0.3 2.2 1 1 1 2 2 2 0 Leucine-rich repeat UBA PF00627.26 EIW82827.1 - 1.8e-25 88.0 5.7 5.4e-15 54.7 0.2 3.3 3 0 0 3 3 3 2 UBA/TS-N domain ubiquitin PF00240.18 EIW82827.1 - 2.3e-20 71.7 1.1 5.5e-20 70.5 0.8 1.6 1 0 0 1 1 1 1 Ubiquitin family XPC-binding PF09280.6 EIW82827.1 - 5.7e-17 60.9 9.3 5.7e-17 60.9 6.4 1.8 2 0 0 2 2 2 1 XPC-binding domain Rad60-SLD PF11976.3 EIW82827.1 - 5.7e-10 38.7 1.3 9.6e-10 38.0 0.9 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EIW82827.1 - 0.00061 19.6 0.1 0.0012 18.6 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.11 EIW82827.1 - 0.0016 17.9 0.5 0.039 13.4 0.0 3.2 3 1 0 3 3 3 1 CUE domain DUF2407 PF10302.4 EIW82827.1 - 0.002 18.2 0.0 0.0039 17.3 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain RepB PF07506.6 EIW82827.1 - 0.005 16.7 0.0 0.061 13.1 0.0 2.3 2 1 0 2 2 2 1 RepB plasmid partitioning protein Ubiquitin_2 PF14560.1 EIW82827.1 - 0.0085 16.3 0.4 0.015 15.5 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain HBS1_N PF08938.5 EIW82827.1 - 0.014 15.4 0.0 2.6 8.2 0.0 2.7 2 0 0 2 2 2 0 HBS1 N-terminus UBA_3 PF09288.5 EIW82827.1 - 0.12 12.0 0.0 3 7.5 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain NIF PF03031.13 EIW82828.1 - 5.6e-53 178.8 0.1 6.3e-53 178.6 0.1 1.0 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD PF12710.2 EIW82828.1 - 0.021 15.0 0.0 0.16 12.0 0.0 1.9 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIW82828.1 - 0.04 14.1 0.1 0.85 9.8 0.0 2.0 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Proteasome PF00227.21 EIW82829.1 - 2.6e-52 176.8 0.1 5.2e-52 175.9 0.1 1.5 1 1 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIW82829.1 - 2.3e-14 52.4 0.2 4.1e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature SKI PF01202.17 EIW82830.1 - 1.5e-09 37.9 0.0 2.5e-07 30.6 0.0 2.3 2 1 0 2 2 2 1 Shikimate kinase AAA_17 PF13207.1 EIW82830.1 - 5.1e-07 30.5 0.0 1e-06 29.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW82830.1 - 3.9e-05 23.5 0.0 8.7e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIW82830.1 - 0.00013 22.3 0.1 0.00035 20.8 0.1 2.0 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 EIW82830.1 - 0.00051 19.2 0.0 0.00092 18.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EIW82830.1 - 0.0011 19.0 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW82830.1 - 0.0018 18.3 0.0 0.0042 17.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.1 EIW82830.1 - 0.002 17.7 0.0 0.0036 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EIW82830.1 - 0.019 14.5 0.0 0.033 13.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_30 PF13604.1 EIW82830.1 - 0.022 14.3 0.9 0.036 13.6 0.1 1.9 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EIW82830.1 - 0.027 14.4 0.1 0.094 12.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EIW82830.1 - 0.032 13.2 0.0 0.043 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EIW82830.1 - 0.037 14.2 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Cytidylate_kin2 PF13189.1 EIW82830.1 - 0.039 13.8 0.0 0.071 13.0 0.0 1.5 2 0 0 2 2 2 0 Cytidylate kinase-like family T2SE PF00437.15 EIW82830.1 - 0.043 12.7 0.0 0.13 11.1 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.22 EIW82830.1 - 0.06 13.6 0.6 0.12 12.6 0.2 1.7 2 1 0 2 2 2 0 ABC transporter AIG1 PF04548.11 EIW82830.1 - 0.093 11.8 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 AIG1 family AAA PF00004.24 EIW82830.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TFIIA_gamma_N PF02268.11 EIW82830.1 - 0.2 11.2 0.8 2.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain Glyoxal_oxid_N PF07250.6 EIW82831.1 - 2.8e-42 144.4 0.1 3.9e-40 137.4 0.0 2.5 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EIW82831.1 - 8.2e-22 77.1 0.2 2.8e-21 75.4 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EIW82831.1 - 1.7e-06 27.7 0.2 0.029 14.1 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Pkinase PF00069.20 EIW82832.1 - 3.8e-24 85.2 0.0 7.5e-24 84.2 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW82832.1 - 7.8e-15 54.6 0.0 6.1e-13 48.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.17 EIW82832.1 - 0.002 17.4 0.0 0.0033 16.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EIW82832.1 - 0.01 15.5 0.0 0.027 14.2 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family SynMuv_product PF06047.6 EIW82833.1 - 2.1e-43 146.3 3.6 2.1e-43 146.3 2.5 2.2 2 0 0 2 2 2 1 Ras-induced vulval development antagonist Ycf1 PF05758.7 EIW82833.1 - 0.47 8.1 5.3 0.58 7.8 3.7 1.2 1 0 0 1 1 1 0 Ycf1 Nucleo_P87 PF07267.6 EIW82833.1 - 1.7 7.2 13.3 4.2 5.9 9.2 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FKBP_C PF00254.23 EIW82834.1 - 4.1e-35 119.6 0.0 5e-35 119.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase FKBP_C PF00254.23 EIW82835.1 - 1.1e-29 102.2 0.0 1.4e-29 101.9 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RCC1 PF00415.13 EIW82836.1 - 6.6e-46 154.3 11.7 3.6e-08 33.5 0.1 7.5 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EIW82836.1 - 9.3e-34 114.3 35.2 3.8e-07 29.5 0.0 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat FKBP_C PF00254.23 EIW82837.1 - 1.6e-33 114.6 0.0 2e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ribosomal_L39 PF00832.15 EIW82838.1 - 7.5e-22 76.5 10.3 1.3e-21 75.7 7.2 1.4 1 0 0 1 1 1 1 Ribosomal L39 protein Tox-REase-3 PF15647.1 EIW82838.1 - 0.1 12.3 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 3 CHD5 PF04420.9 EIW82839.1 - 1.7e-46 157.8 2.3 2.3e-46 157.4 1.6 1.1 1 0 0 1 1 1 1 CHD5-like protein XPA_N PF01286.13 EIW82840.1 - 0.0051 16.4 0.1 0.013 15.1 0.0 1.7 1 0 0 1 1 1 1 XPA protein N-terminal Malate_synthase PF01274.17 EIW82842.1 - 5e-202 671.5 0.0 5.6e-202 671.4 0.0 1.0 1 0 0 1 1 1 1 Malate synthase DDE_Tnp_IS240 PF13610.1 EIW82842.1 - 0.11 12.4 0.2 29 4.6 0.0 3.2 3 0 0 3 3 3 0 DDE domain F-box PF00646.28 EIW82844.1 - 7.8e-07 28.5 0.1 1.8e-06 27.4 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW82844.1 - 8.9e-05 22.1 0.1 0.00018 21.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like OsmC PF02566.14 EIW82845.1 - 1.2e-14 54.3 0.0 4.1e-14 52.5 0.0 1.7 2 0 0 2 2 2 1 OsmC-like protein CPSF_A PF03178.10 EIW82846.1 - 1.4e-95 320.0 0.0 1e-94 317.2 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.4 EIW82846.1 - 8.4e-80 268.3 0.0 1.2e-79 267.7 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF1945 PF09178.5 EIW82846.1 - 0.13 12.1 0.1 0.72 9.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1945) MFS_1 PF07690.11 EIW82847.1 - 1.3e-34 119.5 30.7 1.3e-34 119.5 21.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2686 PF10887.3 EIW82847.1 - 0.053 12.2 0.1 0.083 11.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2686) YqhR PF11085.3 EIW82847.1 - 3.8 6.9 10.1 0.44 10.0 1.6 3.1 3 0 0 3 3 3 0 Conserved membrane protein YqhR Topoisom_bac PF01131.15 EIW82848.1 - 2.5e-95 319.7 0.0 3.1e-95 319.3 0.0 1.1 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EIW82848.1 - 2e-21 75.8 0.0 4e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Toprim domain DUF1253 PF06862.7 EIW82849.1 - 2.8e-143 477.5 0.1 3.6e-143 477.1 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) BRO1 PF03097.13 EIW82850.1 - 1.8e-24 86.1 0.0 2.3e-24 85.8 0.0 1.0 1 0 0 1 1 1 1 BRO1-like domain HAD_2 PF13419.1 EIW82851.1 - 4.8e-19 69.2 0.0 1e-18 68.1 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIW82851.1 - 4.3e-07 30.5 0.1 5.3e-06 27.0 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EIW82851.1 - 0.00012 21.8 0.0 0.032 14.0 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.2 EIW82851.1 - 0.0002 21.5 0.0 0.00024 21.3 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIW82851.1 - 0.017 14.8 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Ctr PF04145.10 EIW82852.1 - 1e-38 132.6 1.2 1.2e-38 132.3 0.8 1.0 1 0 0 1 1 1 1 Ctr copper transporter family Abi PF02517.11 EIW82852.1 - 2.3 8.3 7.7 0.32 11.1 0.3 2.1 2 0 0 2 2 2 0 CAAX protease self-immunity CPSase_sm_chain PF00988.17 EIW82853.1 - 1.3e-44 150.8 0.0 1.9e-44 150.3 0.0 1.2 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain GATase PF00117.23 EIW82853.1 - 1.2e-35 122.7 0.0 1.7e-35 122.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EIW82853.1 - 1.1e-07 31.5 0.0 1.3e-06 28.0 0.0 2.4 2 1 0 2 2 2 1 Peptidase C26 DJ-1_PfpI PF01965.19 EIW82853.1 - 0.0006 19.2 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family Thaumatin PF00314.12 EIW82854.1 - 5.9e-19 68.3 2.4 7.1e-19 68.1 1.6 1.1 1 0 0 1 1 1 1 Thaumatin family AAA PF00004.24 EIW82855.1 - 7.8e-17 61.7 0.0 1.6e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIW82855.1 - 6.2e-05 23.1 1.3 0.009 16.1 0.1 2.8 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EIW82855.1 - 0.0001 23.0 0.1 0.00054 20.7 0.0 2.3 2 1 1 3 3 3 1 AAA domain AAA_19 PF13245.1 EIW82855.1 - 0.00019 21.1 0.3 0.00061 19.4 0.1 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 EIW82855.1 - 0.00021 21.5 0.0 0.00077 19.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIW82855.1 - 0.0011 19.0 0.0 0.0051 16.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EIW82855.1 - 0.0021 17.9 0.0 0.0049 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EIW82855.1 - 0.0041 16.8 0.0 0.012 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Torsin PF06309.6 EIW82855.1 - 0.0056 16.5 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Torsin AAA_28 PF13521.1 EIW82855.1 - 0.0089 16.0 0.1 0.038 13.9 0.1 2.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EIW82855.1 - 0.029 13.9 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Vps36_ESCRT-II PF11605.3 EIW82855.1 - 0.071 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 AAA_14 PF13173.1 EIW82855.1 - 0.073 12.9 0.0 0.41 10.5 0.0 2.3 3 0 0 3 3 3 0 AAA domain Zot PF05707.7 EIW82855.1 - 0.12 11.8 0.1 3.2 7.1 0.1 2.4 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) Solute_trans_a PF03619.11 EIW82856.1 - 2.9e-60 203.9 13.2 3.4e-60 203.7 9.2 1.0 1 0 0 1 1 1 1 Organic solute transporter Ostalpha BSD PF03909.12 EIW82857.1 - 1.7e-10 40.4 0.1 4.4e-10 39.1 0.1 1.7 1 0 0 1 1 1 1 BSD domain Metallophos PF00149.23 EIW82858.1 - 1.6e-09 37.4 0.1 1e-08 34.8 0.1 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Scs3p PF10261.4 EIW82859.1 - 3.8e-39 134.1 12.0 6.4e-37 126.8 8.3 2.7 1 1 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM FA_desaturase PF00487.19 EIW82859.1 - 1.8 7.9 10.3 0.076 12.4 1.0 2.2 2 0 0 2 2 2 0 Fatty acid desaturase DUF3040 PF11239.3 EIW82859.1 - 3.8 7.6 5.2 0.53 10.3 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) PIG-U PF06728.8 EIW82860.1 - 1.1e-97 327.3 28.0 1.2e-97 327.2 19.4 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U WD40 PF00400.27 EIW82861.1 - 1.1e-48 161.4 15.1 7.3e-11 41.5 0.1 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EIW82861.1 - 1.8e-05 24.4 6.1 0.49 10.0 0.1 4.1 3 1 1 4 4 4 3 Transcription factor IIIC subunit delta N-term Homeobox PF00046.24 EIW82862.1 - 2e-18 65.7 0.9 3.5e-18 64.9 0.6 1.4 1 0 0 1 1 1 1 Homeobox domain zf-TRAF PF02176.13 EIW82863.1 - 3.8e-17 62.3 23.6 2.4e-08 34.2 2.7 3.6 2 1 1 3 3 3 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 EIW82863.1 - 5.3e-06 26.3 11.6 5.3e-06 26.3 8.1 3.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW82863.1 - 1.7e-05 24.5 11.3 1.7e-05 24.5 7.8 3.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EIW82863.1 - 2.2e-05 24.0 13.2 2.2e-05 24.0 9.1 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EIW82863.1 - 2.6e-05 23.6 8.2 2.6e-05 23.6 5.7 2.8 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Sina PF03145.11 EIW82863.1 - 0.00056 19.6 23.3 0.22 11.1 0.6 4.4 1 1 4 5 5 5 4 Seven in absentia protein family zf-C3HC4_3 PF13920.1 EIW82863.1 - 0.0047 16.5 9.2 0.0047 16.5 6.4 3.5 3 1 0 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW82863.1 - 0.015 14.9 10.4 0.015 14.9 7.2 3.5 3 1 0 3 3 2 0 zinc-RING finger domain Zip PF02535.17 EIW82863.1 - 1.8 7.4 13.9 2.7 6.9 9.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF605 PF04652.11 EIW82863.1 - 2.4 7.4 19.0 3.4 6.9 13.1 1.1 1 0 0 1 1 1 0 Vta1 like U-box PF04564.10 EIW82863.1 - 2.5 8.1 7.1 0.99 9.4 0.1 3.1 3 0 0 3 3 2 0 U-box domain PAT1 PF09770.4 EIW82863.1 - 7.9 4.5 9.0 11 4.1 6.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 F-box-like PF12937.2 EIW82864.1 - 2.1e-05 24.1 0.9 7.4e-05 22.3 0.6 2.1 1 0 0 1 1 1 1 F-box-like DEAD PF00270.24 EIW82865.1 - 2.8e-35 121.2 0.0 1.1e-34 119.4 0.0 1.9 1 1 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EIW82865.1 - 9.4e-17 60.3 0.1 1.8e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EIW82865.1 - 1.7e-14 53.4 0.0 3.2e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW82865.1 - 0.0094 15.8 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CFIA_Pcf11 PF11526.3 EIW82865.1 - 0.14 12.2 0.1 0.5 10.5 0.1 1.9 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 Pro_isomerase PF00160.16 EIW82866.1 - 2e-44 151.5 0.4 2.4e-44 151.2 0.3 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase PF00069.20 EIW82867.1 - 8e-40 136.6 0.0 1.2e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW82867.1 - 1.6e-24 86.3 0.0 3.8e-24 85.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW82867.1 - 0.00029 20.6 0.5 0.0036 17.0 0.4 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW82867.1 - 0.26 10.2 0.0 0.48 9.3 0.0 1.3 1 0 0 1 1 1 0 Kinase-like AIG1 PF04548.11 EIW82868.1 - 2.9e-11 42.8 0.0 3.4e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 EIW82868.1 - 1.9e-09 37.4 0.0 2e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIW82868.1 - 0.00015 21.0 0.1 0.00024 20.3 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EIW82868.1 - 0.00015 22.2 0.0 0.00017 22.0 0.0 1.4 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 EIW82868.1 - 0.00058 19.2 0.0 0.00083 18.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Septin PF00735.13 EIW82868.1 - 0.028 13.4 0.0 0.031 13.2 0.0 1.1 1 0 0 1 1 1 0 Septin ABC_tran PF00005.22 EIW82868.1 - 0.032 14.5 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_22 PF13401.1 EIW82868.1 - 0.044 13.9 0.1 0.05 13.7 0.1 1.3 1 1 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EIW82868.1 - 0.052 13.3 0.2 0.12 12.1 0.1 1.6 1 1 1 2 2 2 0 Dynamin family FeoB_N PF02421.13 EIW82868.1 - 0.056 12.7 0.0 0.083 12.1 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_10 PF12846.2 EIW82868.1 - 0.089 12.2 0.0 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 EIW82868.1 - 0.11 12.4 0.4 0.21 11.5 0.2 1.4 1 1 0 1 1 1 0 AAA ATPase domain ATP12 PF07542.6 EIW82868.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 ATP12 chaperone protein ALAD PF00490.16 EIW82869.1 - 1.7e-119 398.5 0.0 2e-119 398.3 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Rpr2 PF04032.11 EIW82870.1 - 9.8e-23 79.8 0.0 1.6e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF3408 PF11888.3 EIW82870.1 - 0.056 13.3 3.3 0.076 12.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF164 PF02591.10 EIW82870.1 - 0.069 12.9 1.5 0.29 10.9 1.1 2.0 1 1 0 1 1 1 0 Putative zinc ribbon domain DUF3535 PF12054.3 EIW82870.1 - 0.096 11.2 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3535) DUF605 PF04652.11 EIW82870.1 - 2 7.7 12.0 1.8 7.9 1.2 2.0 2 0 0 2 2 2 0 Vta1 like DPBB_1 PF03330.13 EIW82871.1 - 3.9e-06 26.7 0.1 7.2e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Bromodomain PF00439.20 EIW82872.1 - 5.2e-26 90.3 0.0 1.1e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EIW82872.1 - 1.8e-07 31.1 0.4 4e-07 30.0 0.3 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW82872.1 - 4e-05 23.5 0.1 9.6e-05 22.3 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EIW82872.1 - 0.001 19.1 0.0 0.0059 16.7 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain 2-Hacid_dh_C PF02826.14 EIW82873.1 - 1.1e-46 158.2 0.0 1.8e-46 157.5 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIW82873.1 - 5.4e-19 67.9 0.1 6.9e-19 67.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EIW82873.1 - 9.9e-06 25.4 0.0 2.4e-05 24.2 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 EIW82873.1 - 0.11 13.0 0.0 0.36 11.3 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold EXS PF03124.9 EIW82874.1 - 1.8e-91 306.7 5.1 2.1e-91 306.5 3.6 1.0 1 0 0 1 1 1 1 EXS family tRNA-synt_1 PF00133.17 EIW82875.1 - 2e-218 726.2 0.0 3.2e-218 725.5 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EIW82875.1 - 6.5e-27 94.1 0.1 2e-26 92.5 0.0 1.9 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EIW82875.1 - 1.6e-17 63.2 0.2 5.7e-07 28.5 0.1 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EIW82875.1 - 0.012 14.7 0.0 0.031 13.4 0.0 1.7 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain BAG PF02179.11 EIW82877.1 - 6e-14 51.9 0.1 2.8e-13 49.7 0.1 1.8 2 0 0 2 2 2 1 BAG domain ubiquitin PF00240.18 EIW82877.1 - 3.5e-07 29.5 0.0 6.3e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DEC-1_N PF04625.8 EIW82877.1 - 0.2 10.3 6.2 0.26 9.9 4.3 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Pkinase PF00069.20 EIW82878.1 - 2.8e-48 164.3 0.0 9.4e-48 162.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW82878.1 - 1.7e-33 115.8 0.0 9e-33 113.4 0.0 2.0 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW82878.1 - 6.7e-06 25.2 0.0 1.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW82878.1 - 0.034 13.8 0.0 0.085 12.5 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mis14 PF08641.7 EIW82878.1 - 0.057 13.4 0.2 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Kinetochore protein Mis14 like Sigma70_ner PF04546.8 EIW82878.1 - 0.78 9.3 4.8 1.3 8.5 3.3 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region p450 PF00067.17 EIW82879.1 - 1.3e-70 238.2 0.0 1.5e-70 238.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DIOX_N PF14226.1 EIW82880.1 - 4e-28 98.2 0.0 6.1e-28 97.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIW82880.1 - 4.5e-16 58.9 0.0 9.4e-16 57.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Allantoicase PF03561.10 EIW82881.1 - 1.3e-91 303.9 0.0 2.4e-45 153.7 0.0 2.2 2 0 0 2 2 2 2 Allantoicase repeat Ureidogly_hydro PF04115.7 EIW82881.1 - 7.5e-37 126.2 0.0 1.1e-36 125.7 0.0 1.2 1 0 0 1 1 1 1 Ureidoglycolate hydrolase BRE1 PF08647.6 EIW82882.1 - 1.5e-09 37.7 7.6 1.5e-09 37.7 5.3 7.0 8 1 1 9 9 9 1 BRE1 E3 ubiquitin ligase zf-C3HC4_2 PF13923.1 EIW82882.1 - 2e-06 27.6 11.2 5.1e-06 26.4 7.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW82882.1 - 3.1e-06 26.7 9.7 6.8e-06 25.6 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW82882.1 - 1.4e-05 24.7 11.1 2.9e-05 23.7 7.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIW82882.1 - 0.00015 21.3 11.6 0.00032 20.3 8.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Reo_sigmaC PF04582.7 EIW82882.1 - 0.00016 20.9 0.4 0.00016 20.9 0.3 4.4 4 1 1 5 5 5 2 Reovirus sigma C capsid protein zf-RING_2 PF13639.1 EIW82882.1 - 0.0008 19.1 10.1 0.0016 18.1 7.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_6 PF14835.1 EIW82882.1 - 0.0026 17.5 3.2 0.0051 16.5 2.2 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Rootletin PF15035.1 EIW82882.1 - 0.012 15.6 7.1 0.012 15.6 5.0 5.3 4 2 0 4 4 2 0 Ciliary rootlet component, centrosome cohesion zf-RING_4 PF14570.1 EIW82882.1 - 0.099 12.2 7.6 0.9 9.1 4.8 2.5 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EIW82882.1 - 0.14 12.2 6.8 0.35 10.9 4.7 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger DUF1272 PF06906.6 EIW82882.1 - 0.19 11.6 5.6 0.49 10.2 3.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.1 EIW82882.1 - 0.45 10.4 3.2 1.1 9.1 2.2 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Ribosomal_S9 PF00380.14 EIW82883.1 - 1.7e-33 115.4 0.1 8.9e-31 106.6 0.0 2.2 2 0 0 2 2 2 2 Ribosomal protein S9/S16 CASP_C PF08172.7 EIW82884.1 - 5.9e-69 231.8 0.0 5.9e-69 231.8 0.0 3.9 2 1 2 4 4 4 1 CASP C terminal CCDC92 PF14916.1 EIW82884.1 - 0.023 14.2 1.9 0.13 11.8 0.0 3.2 3 1 0 3 3 3 0 Coiled-coil domain of unknown function TPR_MLP1_2 PF07926.7 EIW82884.1 - 0.028 14.1 40.5 0.17 11.5 3.4 5.6 3 2 2 5 5 5 0 TPR/MLP1/MLP2-like protein Shugoshin_N PF07558.6 EIW82884.1 - 0.075 12.7 0.0 0.075 12.7 0.0 2.8 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region IncA PF04156.9 EIW82884.1 - 0.29 10.7 50.6 1.5 8.3 0.4 5.9 3 1 2 5 5 5 0 IncA protein COG5 PF10392.4 EIW82884.1 - 4.9 7.1 17.4 0.11 12.4 0.8 4.1 2 1 1 4 4 4 0 Golgi transport complex subunit 5 Fmp27_WPPW PF10359.4 EIW82884.1 - 5 5.4 27.5 0.87 7.9 6.7 3.1 2 1 1 3 3 3 0 RNA pol II promoter Fmp27 protein domain WD40_alt PF14077.1 EIW82884.1 - 5.3 6.7 8.6 2.6 7.7 0.2 3.5 3 0 0 3 3 3 0 Alternative WD40 repeat motif DivIVA PF05103.8 EIW82884.1 - 8.9 6.3 44.5 1.7 8.6 3.9 6.4 3 2 3 6 6 6 0 DivIVA protein NAD_kinase PF01513.16 EIW82885.1 - 1.4e-68 230.7 0.0 2.7e-68 229.8 0.0 1.4 1 1 0 1 1 1 1 ATP-NAD kinase DUF2419 PF10343.4 EIW82886.1 - 3.2e-09 36.4 0.0 1.6e-06 27.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2419) YqeY PF09424.5 EIW82887.1 - 3.8e-25 88.3 0.2 4.3e-25 88.2 0.1 1.0 1 0 0 1 1 1 1 Yqey-like protein zf-rbx1 PF12678.2 EIW82888.1 - 9.6e-14 51.2 1.5 1.8e-13 50.3 1.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EIW82888.1 - 1.1e-11 44.3 7.8 1.3e-11 44.0 4.2 2.1 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EIW82888.1 - 5.3e-08 32.3 2.2 9.4e-08 31.5 1.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW82888.1 - 3.3e-06 27.0 1.6 3.3e-06 27.0 1.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW82888.1 - 1.1e-05 25.0 1.6 2.7e-05 23.7 1.1 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIW82888.1 - 1.2e-05 24.8 7.1 0.0002 20.9 5.0 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIW82888.1 - 1.4e-05 24.6 1.9 3.9e-05 23.2 1.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EIW82888.1 - 1.8e-05 24.4 0.7 3.8e-05 23.4 0.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EIW82888.1 - 0.0099 15.7 1.5 0.025 14.4 1.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EIW82888.1 - 0.096 12.6 0.8 0.21 11.5 0.5 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EIW82888.1 - 1.4 8.6 4.0 0.65 9.6 0.9 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Amidohydro_3 PF07969.6 EIW82889.1 - 5.6e-70 236.6 1.1 7.9e-70 236.0 0.8 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 EIW82889.1 - 2.3e-05 24.1 0.1 0.0057 16.3 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EIW82889.1 - 0.00056 20.0 6.3 0.033 14.2 0.0 3.3 3 1 1 4 4 4 2 Amidohydrolase Amidohydro_5 PF13594.1 EIW82889.1 - 0.0012 18.5 0.0 0.0035 17.1 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase SNF2_N PF00176.18 EIW82890.1 - 5.6e-50 169.8 0.0 8.4e-50 169.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW82890.1 - 2.4e-10 40.1 0.0 4.6e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIW82890.1 - 2.9e-07 30.1 0.0 8.1e-07 28.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 EIW82890.1 - 3.2e-06 26.1 0.1 5.8e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EIW82890.1 - 0.0056 16.5 0.0 0.03 14.1 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit IBR PF01485.16 EIW82892.1 - 6.1e-13 48.4 45.9 2.2e-07 30.6 8.0 4.8 4 1 0 4 4 4 2 IBR domain zf-C3HC4 PF00097.20 EIW82892.1 - 0.00034 20.2 1.5 0.00034 20.2 1.1 4.6 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW82892.1 - 0.0011 18.9 6.6 0.0011 18.9 4.6 5.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW82892.1 - 0.0033 17.2 6.4 0.0033 17.2 4.4 4.6 3 2 1 4 4 4 1 Ring finger domain UPF0547 PF10571.4 EIW82892.1 - 0.021 14.4 1.1 0.021 14.4 0.8 4.0 2 2 1 3 3 3 0 Uncharacterised protein family UPF0547 PEPCK_ATP PF01293.15 EIW82893.1 - 3.7e-217 721.4 0.0 4.3e-217 721.1 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_29 PF13555.1 EIW82893.1 - 0.022 14.3 0.0 0.063 12.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DGOK PF05035.7 EIW82893.1 - 0.058 12.1 0.0 0.1 11.3 0.0 1.3 1 0 0 1 1 1 0 2-keto-3-deoxy-galactonokinase AAA_33 PF13671.1 EIW82893.1 - 0.078 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EIW82893.1 - 0.11 11.9 0.2 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIW82893.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF3759 PF12585.3 EIW82894.1 - 0.0087 15.9 1.1 0.019 14.8 0.8 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) F-box-like PF12937.2 EIW82895.1 - 5.2e-09 35.6 0.1 2.8e-08 33.3 0.0 2.4 1 0 0 1 1 1 1 F-box-like DUF3712 PF12505.3 EIW82896.1 - 3e-104 343.9 58.1 2.5e-23 82.4 0.0 9.9 11 0 0 11 11 11 6 Protein of unknown function (DUF3712) LEA_2 PF03168.8 EIW82896.1 - 9.5e-10 38.7 21.1 0.47 10.8 0.0 8.9 9 0 0 9 9 9 4 Late embryogenesis abundant protein FtsH_ext PF06480.10 EIW82897.1 - 2 8.6 5.2 7.3 6.8 0.9 2.6 2 1 0 2 2 2 0 FtsH Extracellular GMC_oxred_N PF00732.14 EIW82898.1 - 8.6e-49 166.2 0.1 8.3e-48 163.0 0.1 2.0 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIW82898.1 - 3e-24 85.9 0.0 5.3e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Rep_fac_C PF08542.6 EIW82899.1 - 1.6e-20 72.8 0.0 4.3e-20 71.5 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EIW82899.1 - 2.7e-11 43.4 0.1 7.1e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit DNA_pol3_delta PF06144.8 EIW82899.1 - 4.6e-05 22.9 0.2 7.4e-05 22.3 0.1 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit RuvB_N PF05496.7 EIW82899.1 - 6.6e-05 22.0 0.2 0.055 12.5 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 EIW82899.1 - 0.00014 22.0 0.2 0.00036 20.7 0.2 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) rpo132 PF12415.3 EIW82899.1 - 0.0027 16.6 0.0 0.0062 15.4 0.0 1.7 1 0 0 1 1 1 1 Poxvirus DNA dependent RNA polymerase AAA_10 PF12846.2 EIW82899.1 - 0.0029 17.0 0.2 0.062 12.7 0.0 2.0 1 1 0 2 2 2 1 AAA-like domain Rad17 PF03215.10 EIW82899.1 - 0.003 16.3 0.0 0.0042 15.8 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_16 PF13191.1 EIW82899.1 - 0.0038 17.2 0.6 0.028 14.4 0.4 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW82899.1 - 0.0067 16.5 0.9 0.043 13.9 0.4 2.4 2 1 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EIW82899.1 - 0.036 14.0 0.4 0.29 11.1 0.3 2.4 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.1 EIW82899.1 - 0.053 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain LSM PF01423.17 EIW82900.1 - 7.4e-14 51.0 0.2 1e-13 50.6 0.2 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EIW82900.1 - 0.0056 16.5 0.1 0.0066 16.3 0.1 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain TPR_11 PF13414.1 EIW82901.1 - 7.5e-32 108.8 18.3 1e-09 37.8 0.1 10.2 8 3 1 9 9 9 6 TPR repeat TPR_1 PF00515.23 EIW82901.1 - 5.4e-28 95.4 3.5 0.00014 21.2 0.0 9.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_16 PF13432.1 EIW82901.1 - 1e-24 86.5 50.1 6.5e-05 23.4 0.1 11.2 11 1 1 13 13 11 7 Tetratricopeptide repeat TPR_14 PF13428.1 EIW82901.1 - 1.4e-23 81.2 44.4 0.019 15.5 0.1 13.9 10 3 4 14 14 14 7 Tetratricopeptide repeat TPR_2 PF07719.12 EIW82901.1 - 6.9e-23 78.6 26.5 0.0011 18.6 0.1 13.0 13 0 0 13 13 13 6 Tetratricopeptide repeat TPR_17 PF13431.1 EIW82901.1 - 7.3e-20 69.4 17.2 0.027 14.6 0.0 13.5 15 0 0 15 15 14 4 Tetratricopeptide repeat TPR_8 PF13181.1 EIW82901.1 - 8.2e-20 69.0 0.1 0.39 10.6 0.0 8.8 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.1 EIW82901.1 - 1.1e-17 63.7 32.4 0.00013 21.8 0.2 9.5 8 2 2 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 EIW82901.1 - 1.7e-12 47.4 34.3 0.0037 17.5 0.3 10.3 9 2 3 12 12 12 5 Tetratricopeptide repeat Apc3 PF12895.2 EIW82901.1 - 4.6e-10 39.4 12.5 0.00087 19.3 0.0 7.8 6 2 2 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EIW82901.1 - 9.7e-08 31.2 21.9 0.013 15.2 0.2 9.1 11 1 0 11 11 9 3 Tetratricopeptide repeat TPR_9 PF13371.1 EIW82901.1 - 7.5e-07 28.9 34.9 0.066 13.0 0.3 9.1 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_6 PF13174.1 EIW82901.1 - 1.7e-05 24.9 20.0 0.84 10.2 0.1 10.2 12 0 0 12 12 9 1 Tetratricopeptide repeat NARP1 PF12569.3 EIW82901.1 - 0.00084 18.2 2.5 2.3 6.8 0.2 5.0 6 0 0 6 6 6 1 NMDA receptor-regulated protein 1 TPR_20 PF14561.1 EIW82901.1 - 8.2 6.6 22.9 2.2 8.4 0.1 6.9 7 3 1 8 8 7 0 Tetratricopeptide repeat AA_permease PF00324.16 EIW82902.1 - 7.1e-112 374.1 43.6 8.6e-112 373.9 30.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIW82902.1 - 1.4e-34 119.4 49.0 1.8e-34 119.0 33.4 1.5 1 1 1 2 2 2 2 Amino acid permease PrgI PF12666.2 EIW82902.1 - 0.00029 20.9 0.3 0.00029 20.9 0.2 3.8 5 1 0 5 5 5 1 PrgI family protein Ribosomal_S7 PF00177.16 EIW82903.1 - 9.7e-40 135.5 1.0 1.2e-39 135.2 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e HeLo PF14479.1 EIW82907.1 - 4.7 6.8 8.4 1.4e+02 2.1 5.6 2.5 1 1 0 1 1 1 0 Prion-inhibition and propagation NAD_binding_9 PF13454.1 EIW82908.1 - 0.0034 17.1 0.0 0.0098 15.6 0.0 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding Rad9 PF04139.8 EIW82909.1 - 9.6e-50 169.0 0.0 1.2e-49 168.7 0.0 1.1 1 0 0 1 1 1 1 Rad9 ABC1 PF03109.11 EIW82910.1 - 2.2e-32 111.5 0.0 4.2e-32 110.6 0.0 1.5 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.17 EIW82910.1 - 0.0007 19.0 0.0 0.0032 16.8 0.0 2.0 2 0 0 2 2 2 1 RIO1 family HECT PF00632.20 EIW82911.1 - 2.2e-89 299.7 0.0 4.1e-89 298.8 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.7 EIW82911.1 - 1.3e-75 254.5 0.0 1.3e-75 254.5 0.0 4.3 4 0 0 4 4 4 2 Domain of Unknown Function (DUF913) DUF908 PF06012.7 EIW82911.1 - 5e-58 196.9 0.3 5e-58 196.9 0.2 2.3 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EIW82911.1 - 4.4e-29 100.5 4.9 4.4e-29 100.5 3.4 3.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4414) UBA PF00627.26 EIW82911.1 - 4.2e-09 35.9 0.0 1.3e-08 34.3 0.0 2.0 1 0 0 1 1 1 1 UBA/TS-N domain ADH_zinc_N PF00107.21 EIW82912.1 - 1.7e-34 118.1 0.6 3e-34 117.3 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW82912.1 - 3.3e-15 57.1 0.0 6.3e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW82912.1 - 6.5e-08 32.3 0.0 1.9e-07 30.7 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EIW82912.1 - 0.0052 16.8 0.3 0.0089 16.0 0.2 1.4 1 0 0 1 1 1 1 NADH(P)-binding RNA_pol_A_bac PF01000.21 EIW82913.1 - 4.3e-29 100.9 0.0 7.8e-29 100.0 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EIW82913.1 - 2.5e-15 55.3 0.0 3.3e-15 54.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF22 PF01629.11 EIW82913.1 - 0.014 14.9 0.1 0.033 13.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF22 RNA_pol_L_2 PF13656.1 EIW82913.1 - 0.1 12.0 0.0 16 5.0 0.0 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain zf-CCCH PF00642.19 EIW82915.1 - 8.1e-14 50.9 15.6 4.5e-07 29.4 1.9 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EIW82915.1 - 0.006 16.4 0.0 0.0097 15.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIW82915.1 - 0.013 15.1 0.0 0.029 14.0 0.0 1.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CART PF06373.6 EIW82915.1 - 1.3 9.0 4.2 7.6 6.5 0.5 2.7 3 0 0 3 3 3 0 Cocaine and amphetamine regulated transcript protein (CART) TPR_1 PF00515.23 EIW82916.1 - 3.6e-24 83.3 22.2 4.7e-05 22.8 0.1 8.1 9 0 0 9 9 8 5 Tetratricopeptide repeat TPR_11 PF13414.1 EIW82916.1 - 3e-23 81.2 18.8 1.3e-08 34.3 1.8 6.0 5 1 1 6 6 6 4 TPR repeat APC8 PF04049.8 EIW82916.1 - 7.7e-22 77.5 0.8 2.5e-21 75.9 0.1 2.0 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_2 PF07719.12 EIW82916.1 - 9.8e-20 68.8 27.8 0.00019 21.0 0.2 9.1 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_8 PF13181.1 EIW82916.1 - 1.4e-16 58.9 17.0 8.3e-05 22.0 0.0 7.9 8 1 1 9 9 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 EIW82916.1 - 1.6e-15 56.7 26.4 7.3e-07 29.0 0.1 6.8 6 1 2 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 EIW82916.1 - 1.8e-14 52.9 16.6 0.02 15.4 0.1 8.4 6 2 3 9 9 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 EIW82916.1 - 1.2e-13 51.3 18.2 0.00023 21.7 0.7 6.6 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_7 PF13176.1 EIW82916.1 - 1.2e-10 40.4 17.9 0.00076 19.0 0.0 6.9 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIW82916.1 - 9.7e-09 34.7 5.8 0.5 10.7 0.2 7.3 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 EIW82916.1 - 1.2e-07 31.4 6.0 0.002 17.9 0.1 5.2 4 2 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIW82916.1 - 1.5e-07 31.6 11.6 0.0041 17.4 0.1 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EIW82916.1 - 7.5e-05 22.7 22.5 0.12 12.5 4.6 5.2 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.5 EIW82916.1 - 0.0044 15.8 0.2 0.011 14.5 0.0 1.7 2 0 0 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.1 EIW82916.1 - 0.025 15.0 20.8 2.6 8.6 0.0 8.4 9 1 0 9 9 8 0 Tetratricopeptide repeat MIT PF04212.13 EIW82916.1 - 0.11 12.4 0.0 0.11 12.4 0.0 3.5 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain FAT PF02259.18 EIW82916.1 - 0.14 11.1 2.9 1.9 7.3 0.0 3.1 2 1 1 3 3 3 0 FAT domain Arc PF03869.9 EIW82916.1 - 0.5 10.0 2.6 23 4.7 0.1 2.5 2 0 0 2 2 2 0 Arc-like DNA binding domain Sel1 PF08238.7 EIW82916.1 - 1 10.0 0.0 1 10.0 0.0 5.1 5 0 0 5 5 4 0 Sel1 repeat GLTSCR1 PF15249.1 EIW82917.1 - 1.3e-16 60.6 0.1 2.1e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Glioma tumor suppressor candidate region Mito_carr PF00153.22 EIW82918.1 - 1.5e-16 59.8 0.0 9.3e-09 34.8 0.0 3.0 2 1 0 2 2 2 2 Mitochondrial carrier protein SNF2_N PF00176.18 EIW82919.1 - 2.1e-51 174.5 0.0 7.9e-44 149.6 0.0 2.5 2 1 1 3 3 3 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW82919.1 - 4.7e-13 48.8 0.0 1.2e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW82919.1 - 1.3e-10 41.3 0.0 5.8e-10 39.3 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sybindin PF04099.7 EIW82920.1 - 1.8e-19 69.9 0.0 2.5e-19 69.3 0.0 1.3 1 1 0 1 1 1 1 Sybindin-like family Ank_2 PF12796.2 EIW82922.1 - 2e-07 31.2 0.0 3.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EIW82922.1 - 3e-07 29.8 0.0 5.1e-06 26.0 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EIW82922.1 - 4.7e-07 29.8 0.4 1.2e-06 28.5 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIW82922.1 - 5.2e-07 30.0 0.1 2.6e-05 24.5 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIW82922.1 - 0.022 14.9 0.0 0.088 13.0 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat Glyco_hydro_61 PF03443.9 EIW82923.1 - 8.1e-62 208.8 0.1 9.2e-62 208.7 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 DUF1168 PF06658.7 EIW82924.1 - 1.3e-40 138.1 14.8 1.7e-40 137.8 10.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) RNase_H2-Ydr279 PF09468.5 EIW82924.1 - 7.6 5.6 8.7 9.5 5.3 6.0 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Tom37_C PF11801.3 EIW82924.1 - 9.7 6.0 7.2 18 5.1 5.0 1.4 1 0 0 1 1 1 0 Tom37 C-terminal domain Ribosomal_S8e PF01201.17 EIW82925.1 - 1.6e-39 135.0 6.2 2.9e-39 134.2 4.3 1.4 1 1 0 1 1 1 1 Ribosomal protein S8e Mer2 PF09074.5 EIW82925.1 - 0.056 13.3 0.1 0.056 13.3 0.1 1.6 2 0 0 2 2 2 0 Mer2 Yip1 PF04893.12 EIW82926.1 - 2.5e-07 30.3 11.8 3.7e-07 29.7 8.2 1.3 1 0 0 1 1 1 1 Yip1 domain Apc4 PF12896.2 EIW82927.1 - 0.005 16.1 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 Hexokinase_1 PF00349.16 EIW82927.1 - 0.3 10.3 0.1 1.4 8.2 0.0 1.9 2 0 0 2 2 2 0 Hexokinase COX17 PF05051.8 EIW82928.1 - 0.0069 16.3 2.2 0.022 14.7 1.5 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) UPF0203 PF05254.7 EIW82928.1 - 0.012 15.4 1.2 0.055 13.3 0.8 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 EIW82928.1 - 0.014 15.1 1.8 0.034 13.9 1.2 1.6 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EIW82928.1 - 0.031 14.3 1.4 0.051 13.6 0.9 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.12 EIW82928.1 - 0.053 13.5 0.7 0.067 13.2 0.5 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Ndufs5 PF10200.4 EIW82928.1 - 0.1 12.5 0.2 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Tetraspannin PF00335.15 EIW82929.1 - 1.2e-05 24.7 6.3 0.00011 21.5 4.4 2.0 1 1 0 1 1 1 1 Tetraspanin family Claudin_2 PF13903.1 EIW82929.1 - 3.4 7.3 9.8 0.16 11.6 2.3 1.9 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction NAD_binding_1 PF00175.16 EIW82930.1 - 3.4e-07 30.8 0.0 0.00046 20.7 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EIW82930.1 - 0.00024 21.0 0.0 0.00073 19.4 0.0 1.8 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Pyridox_oxidase PF01243.15 EIW82930.1 - 0.0056 16.6 0.0 0.37 10.8 0.0 2.8 2 1 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Hist_deacetyl PF00850.14 EIW82931.1 - 1.1e-93 313.9 0.0 1.6e-93 313.4 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EIW82931.1 - 8e-24 84.0 0.1 2e-23 82.7 0.1 1.7 2 0 0 2 2 2 1 Arb2 domain DUF900 PF05990.7 EIW82931.1 - 0.099 11.9 0.2 13 5.0 0.0 2.6 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF900) DUF1749 PF08538.5 EIW82931.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Amidohydro_4 PF13147.1 EIW82932.1 - 2.6e-19 70.2 3.2 2.6e-19 70.2 2.2 3.3 2 2 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 EIW82932.1 - 1.5e-12 47.8 2.2 1.2e-08 34.9 0.0 3.5 3 1 0 3 3 3 2 Amidohydrolase family Amidohydro_5 PF13594.1 EIW82932.1 - 2.7e-09 36.7 1.6 2.4e-07 30.4 0.1 3.0 3 0 0 3 3 3 2 Amidohydrolase Amidohydro_3 PF07969.6 EIW82932.1 - 2.7e-08 33.4 0.7 1.5e-05 24.4 0.0 3.3 3 1 0 3 3 3 2 Amidohydrolase family Amidohydro_4 PF13147.1 EIW82933.1 - 4e-21 76.2 1.7 6.3e-18 65.7 0.3 3.1 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EIW82933.1 - 6.2e-13 48.3 0.4 8.7e-11 41.4 0.1 3.3 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 EIW82933.1 - 2.9e-08 33.7 0.1 3.9e-05 23.4 0.0 2.7 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_3 PF07969.6 EIW82933.1 - 2.4e-06 27.0 4.4 0.00083 18.6 0.0 3.8 3 1 1 4 4 4 2 Amidohydrolase family Rad10 PF03834.9 EIW82934.1 - 2.5e-27 94.3 0.1 3.8e-27 93.7 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EIW82934.1 - 5.4e-07 29.6 0.0 1e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain Amidohydro_4 PF13147.1 EIW82936.1 - 5.1e-20 72.6 2.4 2.7e-18 66.9 0.1 3.7 2 2 0 2 2 2 1 Amidohydrolase Amidohydro_5 PF13594.1 EIW82936.1 - 1.1e-12 47.5 3.0 8.1e-10 38.3 0.1 3.5 3 1 0 3 3 3 2 Amidohydrolase Amidohydro_1 PF01979.15 EIW82936.1 - 2.1e-10 40.7 0.2 2.1e-05 24.3 0.0 2.8 1 1 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 EIW82936.1 - 8.9e-06 25.1 0.4 0.0069 15.6 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family WD40 PF00400.27 EIW82937.1 - 1.3e-13 50.2 17.0 5.2e-08 32.4 0.5 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat OPT PF03169.10 EIW82938.1 - 1.8e-155 518.9 48.7 2e-155 518.7 33.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.3 EIW82938.1 - 5.2 6.8 9.8 0.26 11.1 1.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) MgsA_C PF12002.3 EIW82939.1 - 3.5e-59 199.2 0.5 6.3e-59 198.4 0.3 1.4 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal RuvB_N PF05496.7 EIW82939.1 - 5.6e-17 61.5 0.0 8.6e-17 60.9 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 EIW82939.1 - 3.9e-14 52.9 0.0 1.2e-13 51.4 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIW82939.1 - 9.8e-07 28.5 0.0 1.3e-05 24.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIW82939.1 - 3e-05 24.0 2.0 0.0058 16.6 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.16 EIW82939.1 - 3.8e-05 22.9 0.0 0.17 11.0 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_22 PF13401.1 EIW82939.1 - 5.8e-05 23.2 0.1 0.0022 18.1 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EIW82939.1 - 0.00011 22.0 0.0 0.00032 20.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EIW82939.1 - 0.00041 20.6 0.0 0.00081 19.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EIW82939.1 - 0.00088 19.3 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_28 PF13521.1 EIW82939.1 - 0.0009 19.2 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW82939.1 - 0.001 19.8 0.0 0.0028 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EIW82939.1 - 0.0018 17.8 0.0 0.014 14.8 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.1 EIW82939.1 - 0.0029 17.4 0.0 0.0062 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EIW82939.1 - 0.018 14.4 0.0 2.6 7.3 0.0 2.9 4 0 0 4 4 4 0 AAA-like domain RNA_helicase PF00910.17 EIW82939.1 - 0.033 14.3 0.0 0.086 13.0 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.13 EIW82939.1 - 0.069 12.6 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 EIW82939.1 - 0.081 13.2 0.0 0.25 11.6 0.0 1.9 1 1 0 1 1 1 0 ABC transporter AAA_13 PF13166.1 EIW82939.1 - 0.089 11.2 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.6 EIW82939.1 - 0.15 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EIW82939.1 - 0.16 11.8 0.0 0.43 10.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) Rad17 PF03215.10 EIW82939.1 - 0.21 10.2 0.0 0.7 8.4 0.0 1.7 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein APS_kinase PF01583.15 EIW82940.1 - 9.9e-70 233.2 0.0 1.2e-69 232.9 0.0 1.1 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_33 PF13671.1 EIW82940.1 - 1.1e-06 28.5 0.0 1.5e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW82940.1 - 1.8e-05 25.5 0.1 2.5e-05 25.0 0.1 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIW82940.1 - 0.00014 22.2 0.0 0.00024 21.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EIW82940.1 - 0.0033 16.9 0.0 0.0059 16.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain KTI12 PF08433.5 EIW82940.1 - 0.0049 16.1 0.0 0.0072 15.5 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_25 PF13481.1 EIW82940.1 - 0.085 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIW82940.1 - 0.12 12.3 0.1 0.18 11.7 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 EIW82940.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Pkinase PF00069.20 EIW82941.1 - 1.7e-61 207.6 0.0 1.9e-61 207.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW82941.1 - 1.2e-44 152.3 0.0 1.4e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW82941.1 - 1.3e-06 27.5 0.0 2.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW82941.1 - 6.6e-05 22.7 0.0 0.11 12.1 0.0 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EIW82941.1 - 0.011 14.8 0.0 0.017 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NTP_transferase PF00483.18 EIW82942.1 - 2.2e-08 33.7 0.0 3.9e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EIW82942.1 - 1.7e-05 24.9 0.0 2.4e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 EIW82942.1 - 0.00012 21.4 2.1 0.027 13.9 1.1 3.4 1 1 2 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EIW82942.1 - 0.046 13.2 6.0 0.058 12.9 1.7 2.3 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase eIF-3c_N PF05470.7 EIW82943.1 - 4.2e-179 596.4 26.7 4.2e-179 596.4 18.5 3.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EIW82943.1 - 1e-15 57.9 0.1 1.9e-14 53.8 0.0 2.7 2 0 0 2 2 2 1 PCI domain Ribosomal_S13 PF00416.17 EIW82945.1 - 2.9e-41 140.2 1.8 3.5e-41 139.9 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EIW82945.1 - 0.013 14.1 0.0 0.014 14.0 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.4 EIW82945.1 - 0.14 12.1 0.4 0.32 11.0 0.3 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 CLASP_N PF12348.3 EIW82946.1 - 6.6e-27 94.3 0.0 9.2e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 CLASP N terminal Ribosomal_L34 PF00468.12 EIW82947.1 - 2.1e-19 68.9 12.5 2.6e-19 68.6 8.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L34 Rrn6 PF10214.4 EIW82947.1 - 0.082 11.0 0.1 0.091 10.8 0.1 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DDE_1 PF03184.14 EIW82955.1 - 2.6e-32 111.7 0.0 1.2e-31 109.6 0.0 1.8 1 1 1 2 2 2 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIW82955.1 - 0.00017 21.3 0.0 0.00045 19.9 0.0 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain IncA PF04156.9 EIW82956.1 - 0.095 12.2 5.6 0.16 11.5 3.9 1.3 1 0 0 1 1 1 0 IncA protein TPR_MLP1_2 PF07926.7 EIW82956.1 - 0.21 11.3 7.4 3.3 7.4 5.0 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein TACC PF05010.9 EIW82956.1 - 0.91 9.2 5.6 22 4.7 0.0 2.8 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC) Equine_IAV_S2 PF06502.6 EIW82960.1 - 0.92 9.4 3.5 2.7 7.9 0.7 2.3 1 1 1 2 2 2 0 Equine infectious anaemia virus S2 protein UspB PF10625.4 EIW82965.1 - 0.11 12.3 1.1 0.14 11.9 0.1 1.7 2 0 0 2 2 2 0 Universal stress protein B (UspB) Dimer_Tnp_hAT PF05699.9 EIW82968.1 - 2.3e-16 59.1 0.5 2.6e-16 58.9 0.4 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pex14_N PF04695.8 EIW82972.1 - 0.094 12.7 1.6 0.13 12.2 1.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sporozoite_P67 PF05642.6 EIW82972.1 - 0.29 8.9 3.1 0.32 8.7 2.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MGC-24 PF05283.6 EIW82972.1 - 2.4 7.9 13.1 4.9 6.9 9.1 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) RVT_2 PF07727.9 EIW82973.1 - 2.5e-07 29.8 0.0 3.4e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) UBN2_2 PF14227.1 EIW82974.1 - 4.7e-07 29.3 0.0 1.2e-06 28.1 0.0 1.7 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIW82974.1 - 2e-06 27.5 0.0 3.8e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type ABC2_membrane PF01061.19 EIW82975.1 - 0.26 10.4 4.9 0.082 12.0 0.3 2.3 3 0 0 3 3 3 0 ABC-2 type transporter CcmH PF03918.9 EIW82978.1 - 0.086 11.8 0.2 0.2 10.6 0.2 1.5 1 1 0 1 1 1 0 Cytochrome C biogenesis protein Baculo_IE-1 PF05290.6 EIW82980.1 - 0.031 14.0 0.2 0.088 12.5 0.1 1.8 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) Sgf11 PF08209.6 EIW82982.1 - 0.00057 19.1 0.6 0.0013 17.9 0.4 1.6 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zinc-ribbons_6 PF07191.7 EIW82982.1 - 3.5 7.4 11.9 0.45 10.3 3.5 2.4 2 0 0 2 2 2 0 zinc-ribbons Dimer_Tnp_hAT PF05699.9 EIW82985.1 - 1.5e-06 27.7 0.0 1.5e-06 27.7 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region LT-IIB PF06453.6 EIW82985.1 - 0.11 12.1 0.2 0.12 12.0 0.2 1.0 1 0 0 1 1 1 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) DDE_1 PF03184.14 EIW82986.1 - 2.1e-33 115.3 0.1 3e-33 114.7 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIW82986.1 - 2e-06 27.5 0.1 5.4e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain Endonuc-PvuII PF09225.5 EIW82986.1 - 0.033 13.8 0.1 0.065 12.9 0.0 1.5 1 0 0 1 1 1 0 Restriction endonuclease PvuII CBFB_NFYA PF02045.10 EIW82988.1 - 1e-28 99.6 6.7 1e-28 99.6 4.6 2.2 2 1 0 2 2 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B APC8 PF04049.8 EIW82988.1 - 0.03 14.0 1.0 0.044 13.5 0.7 1.3 1 0 0 1 1 1 0 Anaphase promoting complex subunit 8 / Cdc23 Apc15p PF05841.6 EIW82988.1 - 0.079 13.6 15.3 0.13 12.9 10.6 1.4 1 0 0 1 1 1 0 Apc15p protein DUF4220 PF13968.1 EIW82988.1 - 0.14 11.2 3.5 0.16 11.0 2.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) TFIIA PF03153.8 EIW82988.1 - 0.21 11.4 10.5 0.24 11.2 7.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3818 PF12825.2 EIW82988.1 - 0.22 10.1 3.7 0.27 9.8 2.6 1.1 1 0 0 1 1 1 0 Domain of unknown function in PX-proteins (DUF3818) DUF2360 PF10152.4 EIW82988.1 - 0.39 10.9 6.3 0.55 10.5 4.3 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF605 PF04652.11 EIW82988.1 - 0.48 9.7 11.4 0.51 9.6 7.9 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EIW82988.1 - 1.6 6.8 22.7 2 6.5 15.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Macoilin PF09726.4 EIW82988.1 - 1.6 6.8 8.5 1.6 6.9 5.9 1.1 1 0 0 1 1 1 0 Transmembrane protein eIF_4EBP PF05456.6 EIW82988.1 - 2 8.1 5.1 3.2 7.4 3.5 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) TMEM237 PF15383.1 EIW82988.1 - 3.7 6.6 6.6 4 6.4 4.1 1.3 1 1 0 1 1 1 0 Transmembrane protein 237 HD-ZIP_N PF04618.7 EIW82988.1 - 6.3 7.3 7.0 11 6.6 4.9 1.4 1 0 0 1 1 1 0 HD-ZIP protein N terminus HeH PF12949.2 EIW82989.1 - 7.7e-08 31.7 0.6 7.7e-08 31.7 0.4 1.9 2 0 0 2 2 2 1 HeH/LEM domain CCT_2 PF09425.5 EIW82989.1 - 0.13 11.8 0.2 0.13 11.8 0.1 2.3 2 0 0 2 2 2 0 Divergent CCT motif SAP PF02037.22 EIW82989.1 - 0.22 11.0 1.3 1.2 8.6 0.2 2.7 2 1 0 2 2 2 0 SAP domain PAT1 PF09770.4 EIW82989.1 - 0.46 8.6 10.3 0.52 8.4 7.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EIW82989.1 - 6.4 6.5 9.8 8.1 6.2 6.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PP2C PF00481.16 EIW82990.1 - 4.8e-28 98.2 0.0 6.7e-26 91.2 0.0 2.2 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EIW82990.1 - 1.6e-07 30.9 0.0 5.8e-07 29.1 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C Rax2 PF12768.2 EIW82991.1 - 1e-83 280.8 27.6 1.4e-64 218.0 5.1 4.7 4 0 0 4 4 4 4 Cortical protein marker for cell polarity SH3_1 PF00018.23 EIW82991.1 - 1.8e-09 36.8 0.0 3.6e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIW82991.1 - 1e-05 24.9 0.1 2.3e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain Kelch_1 PF01344.20 EIW82991.1 - 0.0037 16.7 0.1 0.53 9.8 0.0 3.6 4 0 0 4 4 4 1 Kelch motif EphA2_TM PF14575.1 EIW82991.1 - 0.23 11.8 0.1 0.87 10.0 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain RPEL PF02755.10 EIW82993.1 - 1.2e-19 68.9 4.8 3e-09 35.9 1.2 2.4 2 0 0 2 2 2 2 RPEL repeat MCPVI PF02993.9 EIW82993.1 - 0.58 10.2 2.4 0.68 10.0 1.7 1.1 1 0 0 1 1 1 0 Minor capsid protein VI SAM_decarbox PF01536.11 EIW82994.1 - 1e-82 277.5 0.0 1.5e-81 273.6 0.0 2.2 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase PP2C PF00481.16 EIW82995.1 - 1.2e-20 74.0 0.0 1e-18 67.6 0.0 2.1 1 1 0 1 1 1 1 Protein phosphatase 2C Dfp1_Him1_M PF08630.5 EIW82998.1 - 3.1e-21 75.4 0.0 6.3e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 EIW82998.1 - 1e-18 66.7 0.4 2.3e-18 65.5 0.3 1.6 1 0 0 1 1 1 1 DBF zinc finger BRCT PF00533.21 EIW82998.1 - 0.01 15.9 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain SERTA PF06031.8 EIW82998.1 - 0.2 10.9 1.6 0.43 9.9 1.1 1.6 1 0 0 1 1 1 0 SERTA motif Spc97_Spc98 PF04130.8 EIW82999.1 - 4.9e-34 117.5 0.3 2e-33 115.5 0.2 2.0 1 1 0 1 1 1 1 Spc97 / Spc98 family MtrF PF09472.5 EIW83000.1 - 0.13 11.5 0.1 0.28 10.4 0.1 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Dicty_REP PF05086.7 EIW83000.1 - 5.6 4.5 13.2 7.7 4.1 9.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TP6A_N PF04406.9 EIW83001.1 - 3.4e-18 65.0 0.1 9.5e-18 63.6 0.0 1.8 2 0 0 2 2 2 1 Type IIB DNA topoisomerase BTB PF00651.26 EIW83002.1 - 0.01 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain CDC45 PF02724.9 EIW83003.1 - 0.086 10.8 8.7 0.13 10.2 6.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.2 EIW83003.1 - 0.86 7.1 4.7 1.4 6.5 3.3 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DHHW PF14286.1 EIW83003.1 - 2 7.6 9.0 4.5 6.4 6.2 1.5 1 0 0 1 1 1 0 DHHW protein HNF-1_N PF04814.8 EIW83003.1 - 3.9 7.5 8.5 11 6.1 5.9 1.7 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus LUC7 PF03194.10 EIW83003.1 - 5.6 6.4 14.6 20 4.5 0.1 2.2 2 0 0 2 2 2 0 LUC7 N_terminus SKG6 PF08693.5 EIW83004.1 - 2 7.7 4.4 4.5 6.6 3.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Mito_carr PF00153.22 EIW83005.1 - 2.9e-73 241.6 5.1 8.3e-27 92.7 0.1 3.3 3 1 0 3 3 3 3 Mitochondrial carrier protein RhoGAP PF00620.22 EIW83006.1 - 6.1e-30 103.8 0.0 1.1e-29 102.9 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Glyco_hydro_63 PF03200.11 EIW83007.1 - 4.2e-07 28.2 2.1 4.2e-07 28.2 1.4 4.0 4 1 0 4 4 4 2 Mannosyl oligosaccharide glucosidase RhoGEF PF00621.15 EIW83008.1 - 7.5e-38 130.1 0.8 3.1e-37 128.1 0.7 1.9 2 0 0 2 2 2 1 RhoGEF domain PH_10 PF15411.1 EIW83008.1 - 4e-32 110.8 0.0 9.7e-32 109.5 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PB1 PF00564.19 EIW83008.1 - 5.5e-15 54.7 0.1 1.3e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 PB1 domain CDC24 PF06395.6 EIW83008.1 - 1.3e-13 50.8 0.0 2.3e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 CDC24 Calponin Phage_head_fibr PF11133.3 EIW83008.1 - 0.1 11.8 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Head fiber protein Rap1-DNA-bind PF09197.5 EIW83009.1 - 0.00098 19.6 5.9 0.57 10.7 0.5 3.8 2 1 1 3 3 3 2 Rap1, DNA-binding BRCT PF00533.21 EIW83009.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain HK PF02110.10 EIW83010.1 - 6.4e-76 254.7 0.2 4.6e-74 248.6 0.1 2.3 1 1 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EIW83010.1 - 1.1e-57 194.0 0.5 2.4e-57 192.9 0.2 1.7 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI Phos_pyr_kin PF08543.7 EIW83010.1 - 1.5e-05 24.3 0.0 8.2e-05 21.9 0.0 2.0 1 1 1 2 2 2 1 Phosphomethylpyrimidine kinase Peptidase_M19 PF01244.16 EIW83010.1 - 0.015 14.2 0.1 0.034 13.1 0.0 1.6 2 0 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) DUF2436 PF10365.4 EIW83010.1 - 0.033 13.8 0.0 3.3 7.2 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2436) THOC7 PF05615.8 EIW83010.1 - 0.18 12.1 1.0 0.48 10.6 0.2 1.9 2 0 0 2 2 2 0 Tho complex subunit 7 DUF3112 PF11309.3 EIW83011.1 - 0.057 13.2 9.7 0.027 14.2 3.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3112) Orthoreo_P10 PF07204.6 EIW83011.1 - 0.26 11.0 4.6 1.5 8.5 0.1 3.0 2 1 1 3 3 3 0 Orthoreovirus membrane fusion protein p10 SUR7 PF06687.7 EIW83012.1 - 2.5e-15 56.6 14.6 2e-14 53.7 10.1 1.9 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EIW83012.1 - 9.9e-06 25.3 5.9 9.9e-06 25.3 4.1 2.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF2301 PF10063.4 EIW83012.1 - 0.007 16.5 3.7 0.071 13.3 0.4 2.7 2 1 1 3 3 3 1 Uncharacterized integral membrane protein (DUF2301) Clc-like PF07062.7 EIW83012.1 - 0.072 12.3 7.3 0.099 11.8 3.5 1.9 1 1 0 2 2 2 0 Clc-like Lysis_S PF04971.7 EIW83012.1 - 0.17 11.5 1.2 2.5 7.8 0.1 2.7 2 0 0 2 2 2 0 Lysis protein S Oxidored_q2 PF00420.19 EIW83012.1 - 1.1 8.8 10.9 3.4 7.3 3.3 3.0 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF4229 PF14012.1 EIW83012.1 - 9.6 6.1 20.4 0.74 9.7 5.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF4229) Hydrophobin PF01185.13 EIW83013.1 - 5.7e-23 81.1 9.0 6.8e-23 80.9 6.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin DUF747 PF05346.6 EIW83014.1 - 3.7e-110 368.0 7.8 4.7e-110 367.7 5.4 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family RrnaAD PF00398.15 EIW83015.1 - 6.9e-20 71.1 0.0 9e-20 70.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Mnd1 PF03962.10 EIW83016.1 - 2.4e-42 144.7 0.1 2.6e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Mnd1 family TBPIP PF07106.8 EIW83016.1 - 0.023 14.2 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) NPV_P10 PF05531.7 EIW83016.1 - 0.039 14.1 0.2 0.039 14.1 0.1 1.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein V-SNARE PF05008.10 EIW83016.1 - 0.044 13.9 1.9 0.11 12.6 1.3 1.7 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus Fmp27_WPPW PF10359.4 EIW83016.1 - 0.051 11.9 0.1 0.056 11.8 0.1 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain TrmB PF01978.14 EIW83016.1 - 0.13 12.0 0.0 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB DUF4140 PF13600.1 EIW83016.1 - 1.4 9.3 5.0 11 6.4 2.0 2.4 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF1479 PF07350.7 EIW83017.1 - 0.0078 14.7 0.1 0.013 13.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Oxidored_q6 PF01058.17 EIW83018.1 - 1.5e-22 79.6 0.1 2.3e-22 79.0 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Pkinase PF00069.20 EIW83019.1 - 6.2e-53 179.6 0.0 7.7e-53 179.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW83019.1 - 4.7e-22 78.3 0.0 9.3e-22 77.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW83019.1 - 3.8e-06 26.0 0.0 7.9e-06 25.0 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIW83019.1 - 0.00011 22.0 0.0 0.00016 21.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EIW83019.1 - 0.0005 19.2 0.1 0.00074 18.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HhH-GPD PF00730.20 EIW83020.1 - 9.7e-14 51.5 0.0 1.8e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF3614 PF12267.3 EIW83020.1 - 0.23 11.7 3.1 0.46 10.7 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) IER PF05760.7 EIW83020.1 - 2.8 7.8 7.2 0.59 9.9 2.7 1.4 2 0 0 2 2 2 0 Immediate early response protein (IER) SLAC1 PF03595.12 EIW83021.1 - 1.2e-77 260.7 45.8 1.4e-77 260.5 31.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel RseC_MucC PF04246.7 EIW83021.1 - 3 7.4 8.8 0.5 9.9 1.3 2.6 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC PI3_PI4_kinase PF00454.22 EIW83022.1 - 4.6e-35 121.1 0.0 7e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase RRM_1 PF00076.17 EIW83023.1 - 9.5e-14 50.7 0.3 4.2e-06 26.3 0.1 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW83023.1 - 6.1e-12 45.3 0.1 1.2e-05 25.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW83023.1 - 1.5e-06 27.9 0.0 0.00017 21.3 0.0 2.7 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 EIW83023.1 - 0.04 13.6 0.0 1.7 8.4 0.0 2.7 2 1 0 3 3 3 0 Nup53/35/40-type RNA recognition motif ADH_zinc_N PF00107.21 EIW83024.1 - 6.9e-14 51.5 0.0 1.2e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW83024.1 - 1.2e-11 44.3 0.0 2.1e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Herpes_TAF50 PF03326.8 EIW83025.1 - 0.045 12.6 3.7 0.055 12.4 2.6 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) G_glu_transpept PF01019.16 EIW83028.1 - 1.2e-151 505.6 0.0 1.4e-151 505.4 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Peptidase_A22B PF04258.8 EIW83029.1 - 5.1e-70 236.2 1.1 6e-70 236.0 0.7 1.0 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EIW83029.1 - 1.5e-07 30.8 4.7 4.7e-07 29.2 3.3 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1119) Presenilin PF01080.12 EIW83029.1 - 2.1 7.0 6.6 0.09 11.5 0.6 1.6 2 0 0 2 2 2 0 Presenilin GATA PF00320.22 EIW83030.1 - 9.8e-19 66.4 2.3 2.1e-18 65.3 1.6 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EIW83030.1 - 1.2e-12 47.1 1.7 2.6e-12 46.0 1.2 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) Sec7 PF01369.15 EIW83031.1 - 7.6e-38 130.0 0.1 1.7e-37 128.9 0.1 1.5 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EIW83031.1 - 8.1e-28 96.9 0.0 1.6e-27 96.0 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Lzipper-MIP1 PF14389.1 EIW83031.1 - 0.0021 18.1 2.0 0.004 17.2 0.8 2.0 2 0 0 2 2 2 1 Leucine-zipper of ternary complex factor MIP1 PH PF00169.24 EIW83031.1 - 0.0085 16.2 0.0 0.036 14.2 0.0 2.1 2 0 0 2 2 2 1 PH domain Glyco_hydro_76 PF03663.9 EIW83032.1 - 2e-35 122.8 21.7 2.6e-35 122.4 15.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Aldo_ket_red PF00248.16 EIW83033.1 - 2.5e-68 229.9 0.1 2.9e-68 229.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family CPSF73-100_C PF11718.3 EIW83034.1 - 7.8e-55 185.5 0.2 1.3e-54 184.8 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EIW83034.1 - 2.4e-32 111.5 0.0 9.5e-32 109.5 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B PF00753.22 EIW83034.1 - 6.7e-12 45.4 0.5 3.5e-11 43.1 0.4 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 EIW83034.1 - 5e-11 42.2 0.1 9.6e-11 41.3 0.1 1.5 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_2 PF12706.2 EIW83034.1 - 7.1e-09 35.4 1.5 1.1e-08 34.8 0.1 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EIW83034.1 - 3.7e-06 26.7 0.8 0.00011 21.9 0.0 3.2 3 1 0 3 3 3 1 Beta-lactamase superfamily domain BCA_ABC_TP_C PF12399.3 EIW83034.1 - 0.14 11.8 0.4 2.5 7.8 0.0 2.5 2 0 0 2 2 2 0 Branched-chain amino acid ATP-binding cassette transporter Mnd1 PF03962.10 EIW83035.1 - 3.2 7.3 7.4 7.7 6.1 5.2 1.6 1 0 0 1 1 1 0 Mnd1 family WD40 PF00400.27 EIW83036.1 - 8.1e-14 50.8 14.6 0.00012 21.8 0.4 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat zf-MYND PF01753.13 EIW83037.1 - 2.6e-06 27.2 0.9 2.6e-06 27.2 0.6 2.4 2 0 0 2 2 2 1 MYND finger NDUF_B7 PF05676.8 EIW83037.1 - 0.22 10.9 5.4 0.35 10.3 0.1 2.4 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) MFS_1 PF07690.11 EIW83038.1 - 4.3e-40 137.5 18.0 4.3e-40 137.5 12.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 EIW83038.1 - 0.22 9.5 4.5 0.057 11.4 0.4 1.9 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 EIW83038.1 - 3.7 7.3 11.4 0.76 9.6 0.1 4.4 4 2 2 6 6 6 0 MFS_1 like family NUC173 PF08161.7 EIW83040.1 - 5.5e-32 110.7 0.0 1.4e-31 109.3 0.0 1.7 2 0 0 2 2 2 1 NUC173 domain HEAT PF02985.17 EIW83040.1 - 0.068 13.2 5.1 9.3 6.6 0.0 4.7 4 0 0 4 4 4 0 HEAT repeat TRI5 PF06330.6 EIW83041.1 - 1.3e-17 63.4 0.0 1.7e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Acyltransferase PF01553.16 EIW83042.1 - 7.1e-14 51.3 0.0 2.4e-13 49.6 0.0 1.9 2 0 0 2 2 2 1 Acyltransferase adh_short PF00106.20 EIW83043.1 - 6.8e-14 52.1 0.6 6.8e-14 52.1 0.4 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIW83043.1 - 1.1e-05 25.1 0.3 1.9e-05 24.3 0.2 1.4 1 0 0 1 1 1 1 KR domain Amastin PF07344.6 EIW83044.1 - 7.3e-05 22.4 0.9 0.00017 21.2 0.3 2.0 2 0 0 2 2 2 1 Amastin surface glycoprotein COX15-CtaA PF02628.10 EIW83044.1 - 0.0033 16.3 0.1 0.0064 15.3 0.0 1.5 2 0 0 2 2 2 1 Cytochrome oxidase assembly protein L_HGMIC_fpl PF10242.4 EIW83044.1 - 0.0085 16.1 0.0 0.018 15.0 0.0 1.5 1 1 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein DUF2919 PF11143.3 EIW83044.1 - 0.2 11.4 0.2 0.2 11.4 0.1 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2919) DUF2157 PF09925.4 EIW83044.1 - 1.1 8.8 6.9 4.1 7.0 1.4 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) DUF4131 PF13567.1 EIW83044.1 - 3.1 7.1 5.6 0.46 9.8 0.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Tetraspannin PF00335.15 EIW83044.1 - 4.6 6.4 8.5 0.74 9.0 0.1 2.6 3 1 0 3 3 3 0 Tetraspanin family MerC PF03203.9 EIW83044.1 - 7.7 6.9 8.5 0.7 10.2 1.1 2.3 3 0 0 3 3 3 0 MerC mercury resistance protein SURF2 PF05477.6 EIW83045.1 - 0.38 9.8 15.0 0.52 9.4 10.4 1.2 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) FLO_LFY PF01698.11 EIW83045.1 - 1.3 7.7 8.5 1.4 7.7 5.9 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein DDHD PF02862.12 EIW83045.1 - 8.6 6.0 10.3 13 5.5 7.1 1.3 1 0 0 1 1 1 0 DDHD domain Choline_transpo PF04515.7 EIW83046.1 - 1.6e-96 322.9 16.2 1.6e-96 322.9 11.2 2.2 2 1 0 2 2 2 1 Plasma-membrane choline transporter DUF3989 PF13150.1 EIW83046.1 - 9.8 5.7 6.2 14 5.2 0.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) PP2C PF00481.16 EIW83047.1 - 2.9e-64 216.9 0.6 5.8e-49 166.7 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.7 EIW83047.1 - 0.00017 21.3 0.1 0.00093 18.9 0.1 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) W2 PF02020.13 EIW83048.1 - 1.7e-18 66.3 0.1 4.1e-18 65.0 0.1 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Zn_clus PF00172.13 EIW83049.1 - 4e-07 29.8 12.1 7.2e-07 29.0 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EIW83049.1 - 3.9e-06 25.9 0.1 7.1e-06 25.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ETF_alpha PF00766.14 EIW83050.1 - 4.8e-34 115.8 0.2 9e-34 114.9 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 EIW83050.1 - 1e-33 116.3 0.1 2e-33 115.4 0.1 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein domain BMC PF00936.14 EIW83050.1 - 0.0052 16.4 1.8 0.048 13.3 0.2 2.6 2 0 0 2 2 2 1 BMC domain Late_protein_L2 PF00513.13 EIW83050.1 - 0.1 11.4 3.3 0.13 11.0 2.3 1.2 1 0 0 1 1 1 0 Late Protein L2 AAA_12 PF13087.1 EIW83052.1 - 9.8e-24 83.8 0.3 2.2e-23 82.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EIW83052.1 - 5.1e-18 65.5 0.0 5.1e-17 62.2 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW83052.1 - 2.8e-08 33.3 0.0 7.6e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EIW83052.1 - 1.4e-06 28.0 0.0 3.3e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EIW83052.1 - 0.015 14.2 0.0 0.035 13.0 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EIW83052.1 - 0.029 13.7 0.0 0.076 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EIW83052.1 - 0.083 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 KaiC TPR_11 PF13414.1 EIW83053.1 - 2e-20 72.1 2.3 3.1e-11 42.7 0.1 3.1 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 EIW83053.1 - 1.5e-16 58.9 0.8 0.00014 21.5 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EIW83053.1 - 4.5e-16 57.7 0.1 0.0002 20.8 0.0 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EIW83053.1 - 1e-13 51.5 0.6 5e-10 39.7 0.0 4.5 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EIW83053.1 - 4e-10 39.4 10.4 1.3e-05 25.3 0.0 6.3 4 1 3 7 7 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIW83053.1 - 4e-09 35.9 0.2 0.0093 16.0 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIW83053.1 - 5.2e-09 35.9 2.1 0.00058 19.7 0.1 3.6 2 1 2 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIW83053.1 - 4.8e-07 30.0 3.2 0.011 16.0 0.0 4.5 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIW83053.1 - 5.3e-07 28.9 0.0 1.5 8.7 0.0 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIW83053.1 - 5.8e-06 25.7 0.1 1.6 8.6 0.0 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 EIW83053.1 - 4.3e-05 23.2 4.6 1.5 8.8 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EIW83053.1 - 0.00061 19.5 0.0 0.45 10.3 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EIW83053.1 - 0.0036 17.6 5.8 0.57 10.7 0.3 4.3 4 1 0 4 4 3 1 Tetratricopeptide repeat TPR_15 PF13429.1 EIW83053.1 - 0.0068 15.4 4.9 0.0075 15.3 0.1 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EIW83053.1 - 0.022 14.8 0.0 0.38 10.9 0.0 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Coatomer_E PF04733.9 EIW83053.1 - 0.027 13.6 0.0 0.086 12.0 0.0 1.9 2 0 0 2 2 2 0 Coatomer epsilon subunit Herpes_capsid PF06112.6 EIW83053.1 - 0.034 14.1 0.5 0.12 12.4 0.4 1.9 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Fis1_TPR_C PF14853.1 EIW83053.1 - 0.035 13.9 0.0 1.8 8.4 0.0 2.6 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_20 PF14561.1 EIW83053.1 - 0.035 14.2 0.8 2 8.6 0.0 3.8 3 1 2 5 5 4 0 Tetratricopeptide repeat RPN7 PF10602.4 EIW83053.1 - 0.083 12.2 0.0 1.2 8.4 0.0 2.4 1 1 0 1 1 1 0 26S proteasome subunit RPN7 ILVD_EDD PF00920.16 EIW83054.1 - 1.5e-192 640.7 0.0 1.7e-192 640.5 0.0 1.0 1 0 0 1 1 1 1 Dehydratase family ATP_transf PF09830.4 EIW83056.1 - 2.3e-18 65.7 0.0 3.9e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.18 EIW83056.1 - 0.00081 19.8 0.0 0.057 13.9 0.0 2.5 2 0 0 2 2 2 1 HIT domain YcfA PF07927.7 EIW83058.1 - 0.00023 21.0 0.3 0.00077 19.3 0.0 2.0 2 0 0 2 2 2 1 YcfA-like protein NST1 PF13945.1 EIW83058.1 - 0.013 15.6 6.2 0.013 15.6 4.3 2.6 3 0 0 3 3 3 0 Salt tolerance down-regulator SDA1 PF05285.7 EIW83058.1 - 0.03 13.6 15.8 0.035 13.3 6.1 2.2 2 0 0 2 2 2 0 SDA1 PYRIN PF02758.11 EIW83058.1 - 0.057 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain Herpes_LMP2 PF07415.6 EIW83058.1 - 4.2 5.8 3.0 7.6 4.9 2.1 1.3 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein RabGAP-TBC PF00566.13 EIW83059.1 - 3.4e-53 180.2 0.1 4.7e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Cullin_binding PF03556.10 EIW83059.1 - 0.076 13.1 0.7 0.2 11.8 0.3 1.8 2 0 0 2 2 2 0 Cullin binding Ank_5 PF13857.1 EIW83060.1 - 2.3e-14 53.0 0.7 1.1e-09 38.2 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIW83060.1 - 4e-12 46.3 0.0 7.4e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EIW83060.1 - 1e-11 44.0 0.6 0.00017 21.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.19 EIW83060.1 - 1.4e-10 40.9 2.1 2.3e-10 40.3 0.2 2.4 3 0 0 3 3 3 1 IPT/TIG domain Ank_4 PF13637.1 EIW83060.1 - 2.6e-08 34.1 0.1 7.9e-08 32.6 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIW83060.1 - 1.4e-06 28.0 0.3 0.0067 16.5 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Methyltransf_6 PF03737.10 EIW83061.1 - 1.1e-24 87.1 0.2 4.2e-24 85.1 0.2 1.7 1 1 0 1 1 1 1 Demethylmenaquinone methyltransferase VanZ PF04892.7 EIW83063.1 - 6.5e-08 32.6 1.7 6.8e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 VanZ like family DUF2339 PF10101.4 EIW83063.1 - 0.0035 15.7 0.3 0.0045 15.3 0.2 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) Polysacc_synt_C PF14667.1 EIW83063.1 - 0.057 13.2 2.3 0.5 10.1 0.2 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain DUF1275 PF06912.6 EIW83063.1 - 0.12 11.5 2.8 0.17 11.0 1.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1275) Phyto_Pns9_10 PF05878.6 EIW83063.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns9/Pns10 DUF4199 PF13858.1 EIW83063.1 - 1.1 9.2 5.5 0.47 10.3 2.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4199) MerR-DNA-bind PF09278.6 EIW83064.1 - 0.091 13.1 9.1 0.092 13.1 3.1 3.2 2 0 0 2 2 2 0 MerR, DNA binding Phasin PF05597.6 EIW83064.1 - 0.15 11.8 3.5 0.41 10.3 0.2 2.5 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4618 PF15397.1 EIW83064.1 - 1.3 8.3 4.4 11 5.2 0.1 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF4618) Gly-zipper_OmpA PF13436.1 EIW83064.1 - 2.2 7.9 4.9 4.3 7.0 3.4 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain IMS PF00817.15 EIW83065.1 - 2.5e-45 153.9 0.0 4.8e-45 153.0 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EIW83065.1 - 2.9e-15 56.3 0.0 7.5e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EIW83065.1 - 2e-06 27.4 0.1 4.9e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 IMS family HHH motif Nbl1_Borealin_N PF10444.4 EIW83065.1 - 0.11 11.8 0.8 0.34 10.3 0.6 1.9 1 0 0 1 1 1 0 Nbl1 / Borealin N terminal DUF2346 PF09803.4 EIW83065.1 - 0.3 10.9 1.7 10 6.0 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2346) Peptidase_C14 PF00656.17 EIW83066.1 - 1e-11 44.9 0.0 1.7e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Caspase domain APG6 PF04111.7 EIW83067.1 - 1.1e-110 369.6 0.9 1.4e-110 369.2 0.6 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 V_ATPase_I PF01496.14 EIW83067.1 - 0.058 11.2 1.4 0.078 10.8 1.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pinin_SDK_memA PF04696.8 EIW83067.1 - 2.5 7.7 11.6 4.7 6.8 8.1 1.5 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region EssA PF10661.4 EIW83067.1 - 3.2 7.4 9.6 5.5 6.6 6.7 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA GCS PF03074.11 EIW83068.1 - 1.2e-166 554.3 0.0 1.2e-133 445.7 0.0 2.1 1 1 1 2 2 2 2 Glutamate-cysteine ligase GCS2 PF04107.8 EIW83068.1 - 0.04 13.0 0.2 0.13 11.2 0.0 1.8 2 0 0 2 2 2 0 Glutamate-cysteine ligase family 2(GCS2) ATP-synt_DE_N PF02823.11 EIW83069.1 - 1e-19 70.0 0.3 1.5e-19 69.5 0.2 1.2 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF1327 PF07041.6 EIW83069.1 - 0.034 14.0 0.1 0.061 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) 2OG-FeII_Oxy_2 PF13532.1 EIW83070.1 - 1.5e-19 70.6 0.5 3.4e-19 69.4 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TerY-C PF15616.1 EIW83070.1 - 0.15 11.9 3.7 0.34 10.8 2.5 1.5 1 0 0 1 1 1 0 TerY-C metal binding domain Pyridox_oxidase PF01243.15 EIW83072.1 - 5.9e-11 42.2 0.0 1.8e-10 40.6 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase RabGAP-TBC PF00566.13 EIW83073.1 - 2.7e-53 180.6 0.1 2.7e-53 180.6 0.1 1.8 3 0 0 3 3 3 1 Rab-GTPase-TBC domain CALCOCO1 PF07888.6 EIW83073.1 - 0.056 11.7 3.9 0.015 13.6 0.4 1.6 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like TMF_DNA_bd PF12329.3 EIW83073.1 - 0.17 11.7 2.5 0.18 11.6 0.1 2.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Seryl_tRNA_N PF02403.17 EIW83073.1 - 0.18 11.8 3.9 7.2 6.6 0.4 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Cep57_MT_bd PF06657.8 EIW83073.1 - 0.44 10.5 7.4 0.36 10.7 0.7 2.5 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DivIC PF04977.10 EIW83073.1 - 7.4 6.1 7.8 5 6.6 0.0 3.0 2 1 1 3 3 3 0 Septum formation initiator Amidohydro_1 PF01979.15 EIW83074.1 - 1.9e-28 100.0 0.0 1.2e-27 97.4 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EIW83074.1 - 2.3e-26 93.4 0.1 8.7e-14 52.2 0.0 2.6 2 1 1 3 3 3 2 Amidohydrolase Amidohydro_5 PF13594.1 EIW83074.1 - 2e-12 46.7 0.6 4.8e-12 45.5 0.1 1.9 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EIW83074.1 - 2.5e-08 33.5 0.1 0.011 14.9 0.0 3.1 2 1 1 3 3 3 3 Amidohydrolase family Aminotran_3 PF00202.16 EIW83075.1 - 6.1e-105 350.8 0.0 7.4e-105 350.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EIW83075.1 - 0.0055 15.6 0.0 0.0076 15.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIW83075.1 - 0.094 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase zf-RING_2 PF13639.1 EIW83076.1 - 1.1e-12 47.5 4.1 1.9e-12 46.8 2.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EIW83076.1 - 3e-06 27.2 1.1 8.2e-06 25.8 0.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EIW83076.1 - 5.7e-05 22.8 1.9 0.00012 21.8 1.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EIW83076.1 - 6.2e-05 22.5 2.1 9.6e-05 21.8 1.5 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 EIW83076.1 - 7.2e-05 22.7 3.5 0.00013 21.8 2.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW83076.1 - 0.00012 21.7 2.0 0.00022 20.8 1.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIW83076.1 - 0.00029 20.4 1.5 0.00055 19.5 1.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW83076.1 - 0.0018 17.8 1.2 0.0034 17.0 0.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Yip1 PF04893.12 EIW83076.1 - 0.007 15.8 0.5 0.011 15.2 0.0 1.5 2 0 0 2 2 2 1 Yip1 domain FANCL_C PF11793.3 EIW83076.1 - 0.027 14.4 2.7 0.12 12.3 1.8 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EIW83076.1 - 0.22 11.5 1.9 0.42 10.6 1.3 1.5 1 0 0 1 1 1 0 RING-variant domain Josephin PF02099.12 EIW83077.1 - 7.3e-48 162.1 0.0 1.3e-47 161.3 0.0 1.3 1 0 0 1 1 1 1 Josephin UIM PF02809.15 EIW83077.1 - 8.8e-05 21.7 13.0 0.53 10.0 1.0 3.9 3 0 0 3 3 3 3 Ubiquitin interaction motif ATG27 PF09451.5 EIW83078.1 - 2e-48 164.9 0.0 2.4e-48 164.6 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.10 EIW83078.1 - 0.00023 20.2 0.0 0.00035 19.6 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 EIW83078.1 - 0.043 13.5 0.1 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 Cation-independent mannose-6-phosphate receptor repeat Lactamase_B_2 PF12706.2 EIW83080.1 - 2.2e-30 105.6 0.0 2.9e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EIW83080.1 - 6.7e-07 29.1 0.0 1.1e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIW83080.1 - 0.15 11.7 1.3 0.42 10.2 0.4 1.9 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily GPI-anchored PF10342.4 EIW83082.1 - 2.4e-06 27.9 0.4 3.2e-06 27.5 0.3 1.2 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EIW83082.1 - 0.002 17.6 0.0 0.0025 17.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DEAD PF00270.24 EIW83083.1 - 3.8e-39 133.8 0.0 1.6e-38 131.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW83083.1 - 1.6e-20 72.7 0.2 5.4e-20 71.0 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EIW83083.1 - 2.1e-20 72.2 2.6 6.1e-20 70.8 1.8 1.8 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.10 EIW83083.1 - 7.1e-06 25.9 0.4 0.0041 16.9 0.0 3.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DUF4389 PF14333.1 EIW83084.1 - 3.5 7.4 5.2 2.9 7.6 1.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4389) EMP70 PF02990.11 EIW83085.1 - 3.3e-180 600.0 0.0 3.3e-180 600.0 0.0 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 KTI12 PF08433.5 EIW83086.1 - 9.8e-77 257.7 0.0 1.1e-76 257.5 0.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EIW83086.1 - 1.1e-07 31.8 0.0 1.8e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW83086.1 - 0.052 14.3 0.0 0.076 13.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIW83086.1 - 0.076 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain RhoGAP PF00620.22 EIW83088.1 - 2.7e-45 153.6 0.0 1.7e-44 151.1 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain LIM PF00412.17 EIW83088.1 - 8.1e-12 45.0 29.7 7e-08 32.4 6.0 3.5 3 1 0 3 3 3 2 LIM domain C1_1 PF00130.17 EIW83088.1 - 5.8e-06 25.9 11.1 5.8e-06 25.9 7.7 3.7 2 1 2 4 4 4 1 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF972 PF06156.8 EIW83088.1 - 0.024 14.9 0.2 0.024 14.9 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF972) C1_2 PF03107.11 EIW83088.1 - 0.32 11.1 13.8 0.069 13.2 3.3 3.3 3 0 0 3 3 3 0 C1 domain DUF904 PF06005.7 EIW83088.1 - 1.4 9.2 8.4 5.3 7.4 2.3 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Methyltransf_23 PF13489.1 EIW83089.1 - 9.9e-08 31.8 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW83089.1 - 3.4e-06 26.7 0.0 1.9e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW83089.1 - 5.9e-06 26.6 0.0 1.4e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW83089.1 - 0.00062 20.1 0.0 0.0015 18.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW83089.1 - 0.0017 18.6 0.0 0.0053 17.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 EIW83089.1 - 0.0029 17.0 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) FtsJ PF01728.14 EIW83089.1 - 0.0039 17.1 0.0 0.0064 16.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EIW83089.1 - 0.014 14.4 0.0 0.094 11.8 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 EIW83089.1 - 0.024 14.2 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Syndecan PF01034.15 EIW83096.1 - 0.21 11.2 0.3 0.4 10.3 0.2 1.4 1 0 0 1 1 1 0 Syndecan domain Vps53_N PF04100.7 EIW83097.1 - 3.2e-91 305.9 0.8 3.2e-91 305.9 0.6 1.6 2 0 0 2 2 2 1 Vps53-like, N-terminal DUF2450 PF10475.4 EIW83097.1 - 1.2e-08 34.1 7.7 2.7e-08 33.0 5.3 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) IncA PF04156.9 EIW83097.1 - 0.0074 15.8 10.8 0.0074 15.8 7.5 3.2 3 0 0 3 3 3 1 IncA protein Yippee-Mis18 PF03226.9 EIW83098.1 - 4.8e-17 61.7 0.1 6.3e-17 61.4 0.0 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PhnA_Zn_Ribbon PF08274.7 EIW83098.1 - 0.056 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 PhnA Zinc-Ribbon APC_15aa PF05972.6 EIW83098.1 - 0.12 12.4 0.2 0.23 11.5 0.1 1.4 1 0 0 1 1 1 0 APC 15 residue motif RIG-I_C-RD PF11648.3 EIW83098.1 - 0.13 12.0 0.2 1.6 8.5 0.0 2.0 2 0 0 2 2 2 0 C-terminal domain of RIG-I zf-CCHC PF00098.18 EIW83099.1 - 1.8e-10 40.1 26.7 0.00062 19.5 1.1 4.3 4 0 0 4 4 4 4 Zinc knuckle zf-CCHC_2 PF13696.1 EIW83099.1 - 2.6e-05 23.6 16.2 0.027 13.9 0.2 4.0 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.1 EIW83099.1 - 0.00071 19.1 24.6 0.27 10.9 0.6 4.4 4 0 0 4 4 4 4 Zinc knuckle Amnionless PF14828.1 EIW83099.1 - 0.0093 14.4 1.5 0.012 14.1 1.0 1.2 1 0 0 1 1 1 1 Amnionless DUF4206 PF13901.1 EIW83099.1 - 9.5 5.7 14.0 2.1 7.8 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4206) Pterin_4a PF01329.14 EIW83100.1 - 2.4e-12 46.4 0.1 1.4e-11 43.9 0.1 2.0 1 1 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Glyco_hydro_cc PF11790.3 EIW83101.1 - 7.4e-70 235.0 7.9 8.8e-70 234.8 5.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core PWWP PF00855.12 EIW83102.1 - 8.6e-14 51.5 0.2 8.6e-14 51.5 0.1 2.4 2 1 0 2 2 2 1 PWWP domain MMtag PF10159.4 EIW83103.1 - 8.7e-31 105.8 2.8 8.7e-31 105.8 1.9 3.2 3 1 0 3 3 3 1 Kinase phosphorylation protein DUF3381 PF11861.3 EIW83103.1 - 0.5 9.8 17.4 1.4 8.4 12.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3381) DUF4603 PF15376.1 EIW83103.1 - 4.6 4.3 16.5 4.5 4.3 11.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Zn_clus PF00172.13 EIW83105.1 - 5.2e-08 32.6 14.3 5.2e-08 32.6 9.9 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyt-b5 PF00173.23 EIW83107.1 - 1.7e-11 43.7 0.0 2.2e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain G-alpha PF00503.15 EIW83108.1 - 2.3e-126 421.6 0.0 2.9e-126 421.3 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIW83108.1 - 2.6e-16 59.3 0.2 3.9e-11 42.5 0.1 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 EIW83108.1 - 0.00036 20.9 0.2 0.27 11.7 0.0 2.7 2 1 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EIW83108.1 - 0.00076 18.6 3.2 0.014 14.5 0.0 2.5 3 0 0 3 3 3 1 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EIW83108.1 - 0.029 13.9 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EIW83108.1 - 0.029 14.3 0.0 4.6 7.2 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase CPT PF07931.7 EIW83108.1 - 0.031 13.9 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein FtsK_SpoIIIE PF01580.13 EIW83108.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Sensor PF13796.1 EIW83109.1 - 4.1e-08 33.0 12.4 4.1e-08 33.0 8.6 2.7 2 1 1 3 3 3 2 Putative sensor BCS1_N PF08740.6 EIW83110.1 - 1.3e-30 106.4 2.0 1.3e-30 106.4 1.4 1.9 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 EIW83110.1 - 4.5e-15 56.0 0.0 1.1e-06 28.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIW83110.1 - 0.00039 21.2 0.8 0.03 15.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIW83110.1 - 0.0005 20.1 0.0 0.0005 20.1 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EIW83110.1 - 0.00078 18.9 0.1 0.016 14.7 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.8 EIW83110.1 - 0.00089 18.2 0.0 0.002 17.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Viral_helicase1 PF01443.13 EIW83110.1 - 0.005 16.3 0.0 0.012 15.1 0.0 1.7 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 EIW83110.1 - 0.0054 17.0 0.1 0.22 11.8 0.0 2.7 3 0 0 3 3 3 1 ABC transporter Lipase_GDSL PF00657.17 EIW83110.1 - 0.024 14.4 0.0 0.14 11.9 0.0 2.1 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase FtsK_SpoIIIE PF01580.13 EIW83110.1 - 0.031 13.7 1.2 8 5.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 EIW83110.1 - 0.043 14.1 14.0 15 5.8 9.4 2.7 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 EIW83110.1 - 0.047 13.4 0.0 0.22 11.2 0.0 2.2 1 0 0 1 1 1 0 Part of AAA domain AAA_33 PF13671.1 EIW83110.1 - 0.048 13.5 0.0 0.048 13.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF4262 PF14081.1 EIW83110.1 - 0.083 13.0 0.1 0.32 11.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4262) DDRGK PF09756.4 EIW83110.1 - 0.24 10.7 21.3 26 4.1 17.2 2.2 2 0 0 2 2 2 0 DDRGK domain DIOX_N PF14226.1 EIW83111.1 - 8.4e-28 97.2 0.0 1.3e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIW83111.1 - 1.4e-17 63.8 0.0 2.6e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Sec2p PF06428.6 EIW83113.1 - 5.4e-08 32.6 11.2 5.4e-08 32.6 7.7 2.6 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p Stb3 PF10330.4 EIW83113.1 - 0.032 13.9 0.1 0.073 12.7 0.1 1.5 1 0 0 1 1 1 0 Putative Sin3 binding protein RP-C PF03428.8 EIW83113.1 - 0.4 10.0 9.0 0.71 9.2 0.1 2.9 2 1 1 3 3 3 0 Replication protein C N-terminal domain DUF572 PF04502.8 EIW83113.1 - 0.46 9.6 12.9 0.45 9.6 3.7 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) TMEM117 PF15113.1 EIW83114.1 - 0.24 9.9 7.1 0.33 9.4 5.0 1.2 1 0 0 1 1 1 0 TMEM117 protein family Sec34 PF04136.10 EIW83115.1 - 1.4e-32 112.5 0.1 3.8e-32 111.1 0.1 1.7 1 0 0 1 1 1 1 Sec34-like family DUF2348 PF09807.4 EIW83116.1 - 1.8e-16 60.0 0.0 3.1e-16 59.2 0.0 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) Elong_Iki1 PF10483.4 EIW83116.1 - 0.0051 16.2 0.0 0.016 14.5 0.0 1.7 1 1 0 1 1 1 1 Elongator subunit Iki1 Trs65 PF12735.2 EIW83117.1 - 1.3e-20 73.9 4.4 9.4e-19 67.8 0.6 2.9 2 2 0 2 2 2 2 TRAPP trafficking subunit Trs65 PX PF00787.19 EIW83118.1 - 1.1e-25 89.5 0.0 1.5e-25 89.1 0.0 1.2 1 0 0 1 1 1 1 PX domain GATase_5 PF13507.1 EIW83119.1 - 3.1e-97 324.5 0.0 4.5e-97 324.0 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EIW83119.1 - 3e-49 166.9 0.3 1.8e-27 96.2 0.1 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EIW83119.1 - 2.5e-25 88.5 0.0 9.5e-25 86.6 0.0 2.1 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain adh_short PF00106.20 EIW83122.1 - 1.5e-10 41.2 0.2 3.7e-10 39.9 0.0 1.7 2 1 1 3 3 3 1 short chain dehydrogenase KR PF08659.5 EIW83122.1 - 0.00011 21.9 0.0 0.00024 20.8 0.0 1.5 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIW83122.1 - 0.017 14.9 0.0 0.046 13.4 0.0 1.7 2 1 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase GBP_PSP PF02425.10 EIW83122.1 - 0.044 13.3 0.1 0.092 12.2 0.1 1.6 1 0 0 1 1 1 0 Paralytic/GBP/PSP peptide zf-SNAP50_C PF12251.3 EIW83123.1 - 1.4e-27 96.3 0.0 2.8e-27 95.3 0.0 1.4 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal ATP-synt_B PF00430.13 EIW83123.1 - 0.09 12.5 0.8 0.21 11.3 0.5 1.5 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) RAMP PF04901.8 EIW83123.1 - 0.092 12.4 0.2 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 Receptor activity modifying family RRM_1 PF00076.17 EIW83124.1 - 2.4e-09 36.6 0.0 0.00012 21.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.15 EIW83124.1 - 2.5e-07 30.2 0.2 5.8e-07 29.0 0.1 1.6 1 0 0 1 1 1 1 Surp module RRM_6 PF14259.1 EIW83124.1 - 4.4e-07 29.7 0.0 3.8e-06 26.7 0.0 2.2 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW83124.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EIW83124.1 - 0.084 13.1 0.1 0.23 11.7 0.1 1.8 1 1 0 1 1 1 0 RNA polymerase II-binding domain. CTK3 PF12243.3 EIW83124.1 - 0.093 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 H-K_ATPase_N PF09040.6 EIW83124.1 - 0.15 12.2 0.5 0.3 11.2 0.4 1.4 1 0 0 1 1 1 0 Gastric H+/K+-ATPase, N terminal domain DUF566 PF04484.7 EIW83124.1 - 4.3 6.7 19.1 11 5.3 13.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF566) KH_1 PF00013.24 EIW83125.1 - 4.1e-74 244.1 35.9 4.7e-12 45.3 0.4 12.4 12 1 0 12 12 12 9 KH domain KH_3 PF13014.1 EIW83125.1 - 1.7e-51 171.0 25.2 9.1e-10 37.9 0.1 12.5 13 0 0 13 13 13 9 KH domain KH_2 PF07650.12 EIW83125.1 - 6.5e-11 41.6 12.6 0.45 10.1 0.0 7.1 6 1 0 6 6 6 5 KH domain SLS PF14611.1 EIW83125.1 - 2e-08 33.9 21.9 0.086 12.2 0.0 9.0 8 2 2 10 10 10 4 Mitochondrial inner-membrane-bound regulator BMC PF00936.14 EIW83125.1 - 0.027 14.1 20.4 0.089 12.4 0.3 6.9 9 0 0 9 9 9 0 BMC domain Aldo_ket_red PF00248.16 EIW83126.1 - 1.2e-42 145.6 0.0 1.8e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EIW83127.1 - 1.2e-50 171.9 0.0 1.5e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Amidohydro_4 PF13147.1 EIW83128.1 - 1.3e-17 64.7 7.0 6.4e-17 62.4 0.4 3.6 2 2 0 2 2 2 1 Amidohydrolase Amidohydro_5 PF13594.1 EIW83128.1 - 5.3e-10 38.9 0.3 7.4e-08 32.1 0.0 2.7 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 EIW83128.1 - 5.1e-08 32.9 0.3 8.6e-05 22.3 0.0 3.2 4 0 0 4 4 4 2 Amidohydrolase family Amidohydro_3 PF07969.6 EIW83128.1 - 1.7e-05 24.2 0.1 0.0085 15.3 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family HNF-1A_C PF04813.7 EIW83129.1 - 0.017 15.3 0.5 0.047 13.9 0.3 1.7 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus SLT PF01464.15 EIW83130.1 - 2.9e-09 36.4 0.0 6.8e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 Transglycosylase SLT domain Cyclin PF08613.6 EIW83131.1 - 2.1e-08 34.7 0.0 1.1e-06 29.1 0.0 2.6 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EIW83131.1 - 0.031 13.8 0.0 0.23 11.0 0.0 2.0 2 0 0 2 2 2 0 Cyclin, N-terminal domain Fungal_trans_2 PF11951.3 EIW83133.1 - 1.3e-43 149.1 0.2 1.7e-43 148.7 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW83133.1 - 1.8e-07 30.9 8.3 3.5e-07 30.0 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PilJ PF13675.1 EIW83133.1 - 0.076 13.3 1.0 0.21 11.9 0.2 2.0 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Pkinase PF00069.20 EIW83136.1 - 9.7e-62 208.4 0.0 1.2e-61 208.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW83136.1 - 3.4e-35 121.3 0.0 4.3e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW83136.1 - 2.2e-07 30.1 0.0 1.3e-05 24.3 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Seadorna_VP7 PF07387.6 EIW83136.1 - 0.082 11.7 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EIW83136.1 - 0.13 11.9 0.0 1 9.0 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Acetyltransf_1 PF00583.19 EIW83137.1 - 8.9e-12 44.8 0.0 1.3e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EIW83137.1 - 8.7e-09 35.4 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIW83137.1 - 1.7e-05 24.8 0.0 2.2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIW83137.1 - 4e-05 23.5 0.0 5.3e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIW83137.1 - 0.0004 20.4 0.0 0.0006 19.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIW83137.1 - 0.00067 19.8 0.0 0.00081 19.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIW83137.1 - 0.0087 15.8 0.0 0.013 15.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein zf-C2H2 PF00096.21 EIW83138.1 - 2.3e-10 40.1 9.3 2.5e-05 24.3 0.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW83138.1 - 1.2e-09 37.8 6.3 7.6e-05 22.7 0.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIW83138.1 - 2.2e-08 33.9 6.1 2.1e-06 27.7 0.5 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-met PF12874.2 EIW83138.1 - 0.0022 18.1 0.5 1.2 9.4 0.3 2.8 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIW83138.1 - 0.053 13.6 7.8 0.12 12.5 0.4 2.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EIW83138.1 - 1.9 8.8 8.7 1.2 9.5 0.6 3.0 3 0 0 3 3 3 0 C2H2-type zinc-finger domain DNA_ligase_A_M PF01068.16 EIW83139.1 - 2.5e-39 134.7 0.3 1.3e-36 125.8 0.0 2.2 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EIW83139.1 - 1.2e-33 116.3 0.0 2.1e-33 115.6 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EIW83139.1 - 1e-19 70.7 0.0 3.8e-19 68.9 0.0 2.0 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region Pyrid_oxidase_2 PF13883.1 EIW83140.1 - 3.8e-16 59.3 0.2 3.9e-16 59.2 0.1 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase YjbE PF11106.3 EIW83141.1 - 0.078 12.9 1.9 0.22 11.5 1.4 1.8 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE BolA PF01722.13 EIW83142.1 - 8e-31 105.8 0.3 9.5e-31 105.5 0.2 1.0 1 0 0 1 1 1 1 BolA-like protein zf-C2H2 PF00096.21 EIW83143.1 - 7.5e-13 48.0 4.9 5.9e-07 29.4 0.3 2.4 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW83143.1 - 1.8e-11 43.7 2.6 1.3e-05 25.2 0.0 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIW83143.1 - 9.8e-08 31.8 3.6 0.00048 20.2 0.2 2.4 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIW83143.1 - 5e-05 23.3 0.1 0.00014 21.9 0.1 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 EIW83143.1 - 0.00073 19.1 1.1 0.06 13.0 0.1 2.3 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-met PF12874.2 EIW83143.1 - 0.0026 17.9 0.2 0.0074 16.4 0.2 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-BED PF02892.10 EIW83143.1 - 0.022 14.5 0.9 0.097 12.4 0.1 2.1 2 0 0 2 2 2 0 BED zinc finger Zn-ribbon_8 PF09723.5 EIW83143.1 - 0.066 13.1 1.7 3.3 7.7 0.2 2.3 2 0 0 2 2 2 0 Zinc ribbon domain zf-TRAF PF02176.13 EIW83143.1 - 0.072 13.4 0.2 0.11 12.9 0.2 1.3 1 0 0 1 1 1 0 TRAF-type zinc finger zf-C2H2_6 PF13912.1 EIW83143.1 - 0.25 11.3 2.1 7.3 6.6 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Pkinase PF00069.20 EIW83144.1 - 1.2e-55 188.4 0.0 7.7e-37 126.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW83144.1 - 2.4e-24 85.8 0.0 2.3e-16 59.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIW83144.1 - 0.00027 20.0 0.1 0.0017 17.4 0.0 2.2 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EIW83144.1 - 0.013 15.2 2.1 0.016 14.9 0.4 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EIW83144.1 - 0.035 12.9 0.2 0.051 12.3 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Homeobox PF00046.24 EIW83145.1 - 2.6e-16 58.9 3.2 2.6e-16 58.9 2.2 1.7 2 0 0 2 2 2 1 Homeobox domain Homeobox_KN PF05920.6 EIW83145.1 - 0.0082 15.8 1.4 0.012 15.2 0.1 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homez PF11569.3 EIW83145.1 - 0.078 12.0 0.1 0.14 11.2 0.1 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez ABC_tran PF00005.22 EIW83146.1 - 3.8e-48 163.2 0.0 1.8e-27 96.2 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIW83146.1 - 1.8e-15 57.6 0.6 0.011 15.7 0.0 4.2 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 EIW83146.1 - 3.6e-13 49.2 0.0 1.5e-05 24.3 0.0 3.7 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain Chromo PF00385.19 EIW83146.1 - 1.7e-09 37.1 0.1 3.4e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA_17 PF13207.1 EIW83146.1 - 1e-06 29.5 0.0 0.038 14.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EIW83146.1 - 1.3e-06 28.9 0.0 0.012 16.1 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EIW83146.1 - 2.4e-06 26.9 1.7 0.067 12.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EIW83146.1 - 2.6e-06 27.3 0.0 0.023 14.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.1 EIW83146.1 - 3.4e-06 26.9 0.0 0.0031 17.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain HEAT PF02985.17 EIW83146.1 - 1.1e-05 25.1 1.7 0.88 9.8 0.1 5.0 5 0 0 5 5 4 2 HEAT repeat AAA_16 PF13191.1 EIW83146.1 - 1.2e-05 25.3 1.4 0.11 12.4 0.1 3.9 3 2 0 3 3 3 1 AAA ATPase domain HEAT_2 PF13646.1 EIW83146.1 - 1.9e-05 24.8 3.6 0.47 10.7 0.0 3.9 1 1 2 3 3 3 2 HEAT repeats DUF258 PF03193.11 EIW83146.1 - 3.5e-05 23.0 0.0 0.022 13.9 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 EIW83146.1 - 3.9e-05 24.0 0.0 0.057 13.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EIW83146.1 - 8.9e-05 22.4 0.2 0.58 9.9 0.0 3.0 3 0 0 3 3 3 2 Domain of unknown function DUF87 MobB PF03205.9 EIW83146.1 - 9e-05 22.1 0.1 0.12 12.0 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EIW83146.1 - 9.7e-05 22.3 0.0 0.41 10.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EIW83146.1 - 0.0001 21.1 0.6 0.11 11.3 0.0 2.5 2 0 0 2 2 2 2 ArgK protein AAA_22 PF13401.1 EIW83146.1 - 0.00014 21.9 0.0 0.5 10.4 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_10 PF12846.2 EIW83146.1 - 0.00021 20.8 0.6 0.74 9.1 0.0 2.6 2 0 0 2 2 2 2 AAA-like domain AAA_18 PF13238.1 EIW83146.1 - 0.00033 20.9 0.0 0.95 9.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EIW83146.1 - 0.00057 19.5 0.2 0.15 11.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain Tudor-knot PF11717.3 EIW83146.1 - 0.0023 17.5 0.1 0.0049 16.5 0.1 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain CLASP_N PF12348.3 EIW83146.1 - 0.0035 16.7 0.1 1.5 8.0 0.0 2.9 2 1 1 3 3 3 1 CLASP N terminal Dynamin_N PF00350.18 EIW83146.1 - 0.0043 16.8 0.0 0.092 12.5 0.0 2.8 3 0 0 3 3 3 1 Dynamin family AAA_14 PF13173.1 EIW83146.1 - 0.0043 16.9 0.0 11 5.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EIW83146.1 - 0.0067 15.8 0.1 6.2 6.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.1 EIW83146.1 - 0.0086 15.6 0.3 9.8 5.7 0.0 3.4 3 1 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 EIW83146.1 - 0.0086 16.2 0.1 3.6 7.8 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_13 PF13166.1 EIW83146.1 - 0.011 14.1 0.0 1.3 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain UME PF08064.8 EIW83146.1 - 0.021 14.7 0.0 0.65 9.9 0.0 2.4 2 0 0 2 2 2 0 UME (NUC010) domain HEAT_EZ PF13513.1 EIW83146.1 - 0.026 15.0 4.7 0.5 10.9 0.2 4.3 3 1 1 4 4 3 0 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EIW83146.1 - 0.026 14.9 0.0 61 4.0 0.0 3.5 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region ATP_bind_1 PF03029.12 EIW83146.1 - 0.033 13.7 0.3 9.1 5.7 0.1 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Arf PF00025.16 EIW83146.1 - 0.05 12.8 0.0 2.3 7.4 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family cobW PF02492.14 EIW83146.1 - 0.052 13.0 0.2 12 5.3 0.1 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EIW83146.1 - 0.054 12.9 0.1 5.7 6.4 0.0 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF3584 PF12128.3 EIW83146.1 - 0.068 10.5 1.6 2.2 5.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_15 PF13175.1 EIW83146.1 - 0.07 12.1 0.0 12 4.7 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain Arch_ATPase PF01637.13 EIW83146.1 - 0.071 12.8 0.3 17 5.0 0.1 2.6 2 0 0 2 2 2 0 Archaeal ATPase AAA_5 PF07728.9 EIW83146.1 - 0.071 12.8 0.4 48 3.6 0.1 3.9 4 0 0 4 4 3 0 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EIW83146.1 - 0.081 12.0 0.3 1.9 7.5 0.1 2.8 3 0 0 3 3 3 0 Zeta toxin G-alpha PF00503.15 EIW83146.1 - 0.13 10.9 0.0 0.34 9.5 0.0 1.6 2 0 0 2 2 1 0 G-protein alpha subunit MMS19_C PF12460.3 EIW83146.1 - 0.15 10.7 0.2 0.46 9.1 0.1 1.8 2 0 0 2 2 2 0 RNAPII transcription regulator C-terminal AAA_24 PF13479.1 EIW83146.1 - 0.16 11.5 1.0 10 5.6 0.1 2.3 2 0 0 2 2 2 0 AAA domain Adaptin_N PF01602.15 EIW83146.1 - 0.23 9.7 1.1 1.1 7.5 0.8 1.9 1 1 0 1 1 1 0 Adaptin N terminal region Glyco_hydro_18 PF00704.23 EIW83147.1 - 8.6e-84 281.9 0.9 1.7e-45 155.9 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 GTP_EFTU PF00009.22 EIW83148.1 - 2.4e-23 82.5 0.0 4.3e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EIW83148.1 - 5.2e-16 58.6 0.6 1.1e-15 57.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EIW83148.1 - 1e-07 31.9 3.6 2.8e-07 30.5 0.4 3.2 3 1 1 4 4 4 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EIW83148.1 - 0.0043 16.6 0.3 0.022 14.3 0.2 2.3 1 1 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EIW83148.1 - 0.027 14.4 0.0 0.075 12.9 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.9 EIW83148.1 - 0.051 13.2 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Miro PF08477.8 EIW83148.1 - 0.17 12.3 0.5 3.6 8.1 0.3 2.8 1 1 0 1 1 1 0 Miro-like protein LMBR1 PF04791.11 EIW83149.1 - 1.6 7.2 4.4 2.2 6.7 3.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Form_Nir_trans PF01226.12 EIW83150.1 - 1.6e-66 223.7 14.5 1.8e-66 223.6 10.0 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter DSPc PF00782.15 EIW83151.1 - 3.9e-26 91.2 0.0 4.9e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIW83151.1 - 7.1e-05 22.2 0.0 9.9e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Abhydrolase_3 PF07859.8 EIW83152.1 - 5.7e-23 81.6 0.0 8.8e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIW83152.1 - 1e-11 44.1 0.0 2e-11 43.1 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EIW83152.1 - 0.0034 17.1 0.0 0.0049 16.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EIW83152.1 - 0.26 9.9 0.8 1.4 7.5 0.6 1.9 1 1 0 1 1 1 0 Carboxylesterase family DUF3128 PF11326.3 EIW83153.1 - 1.6e-19 69.8 1.1 2e-19 69.4 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) Spo7 PF03907.8 EIW83153.1 - 0.12 12.0 0.1 0.13 11.8 0.1 1.1 1 0 0 1 1 1 0 Spo7-like protein MCM PF00493.18 EIW83154.1 - 9.3e-139 461.8 0.3 1.3e-138 461.3 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EIW83154.1 - 3.6e-29 101.7 31.7 3.6e-29 101.7 22.0 2.4 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EIW83154.1 - 1.8e-16 60.6 0.0 4.3e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EIW83154.1 - 1.2e-07 31.1 0.0 2.6e-06 26.7 0.0 2.4 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EIW83154.1 - 3.7e-06 26.6 0.0 7.5e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EIW83154.1 - 0.0029 17.1 0.1 0.017 14.5 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EIW83154.1 - 0.0055 16.3 0.1 0.053 13.1 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Yippee-Mis18 PF03226.9 EIW83154.1 - 0.023 14.7 0.0 0.052 13.5 0.0 1.6 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly CHCH PF06747.8 EIW83155.1 - 2.2e-08 33.8 4.9 2.2e-08 33.8 3.4 1.5 2 0 0 2 2 2 1 CHCH domain GCK PF07802.6 EIW83155.1 - 0.02 15.0 1.6 0.028 14.5 1.1 1.2 1 0 0 1 1 1 0 GCK domain DctQ PF04290.7 EIW83156.1 - 0.018 14.8 2.5 0.018 14.8 1.7 2.2 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component Ring_hydroxyl_B PF00866.13 EIW83157.1 - 0.35 10.5 10.1 1.4 8.5 5.1 2.3 2 1 0 2 2 2 0 Ring hydroxylating beta subunit Atg14 PF10186.4 EIW83157.1 - 2.2 7.1 13.9 3.2 6.6 9.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Phage_GPO PF05929.6 EIW83157.1 - 3.7 6.7 6.4 5.1 6.2 4.4 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Borrelia_P83 PF05262.6 EIW83157.1 - 5.7 5.0 11.9 7.2 4.7 8.3 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Pkinase PF00069.20 EIW83158.1 - 1.8e-55 187.8 0.0 2.2e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW83158.1 - 6.8e-18 64.6 0.0 1.2e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW83158.1 - 9.6e-09 35.3 0.1 9e-05 22.3 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EIW83158.1 - 0.0026 17.1 0.1 0.0043 16.4 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EIW83158.1 - 0.018 14.5 0.0 0.044 13.3 0.0 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase Sec7 PF01369.15 EIW83159.1 - 1.4e-23 83.5 0.0 2.4e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Fe-ADH PF00465.14 EIW83160.1 - 1.3e-69 234.5 0.0 1.6e-69 234.3 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EIW83160.1 - 3.4e-16 59.3 0.0 5.4e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 EIW83160.1 - 0.0019 17.1 0.1 0.023 13.6 0.1 2.1 2 0 0 2 2 2 1 3-dehydroquinate synthase Cation_efflux PF01545.16 EIW83161.1 - 2.1e-48 164.8 4.4 3.9e-48 163.9 3.1 1.5 1 1 0 1 1 1 1 Cation efflux family DUF262 PF03235.9 EIW83162.1 - 1.7e-16 60.8 0.3 3.2e-16 59.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF262 Mg_trans_NIPA PF05653.9 EIW83163.1 - 8.7e-18 64.3 12.3 8.2e-09 34.8 0.6 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EIW83163.1 - 1.5e-05 25.1 5.6 1.5e-05 25.1 3.9 4.3 3 2 1 4 4 4 1 Multidrug resistance efflux transporter SieB PF14163.1 EIW83163.1 - 8.3e-05 22.1 1.1 0.042 13.4 0.0 3.1 3 0 0 3 3 3 2 Superinfection exclusion protein B EamA PF00892.15 EIW83163.1 - 0.0023 17.9 8.1 0.0023 17.9 5.6 3.3 3 1 0 3 3 3 2 EamA-like transporter family Neur_chan_memb PF02932.11 EIW83163.1 - 0.052 13.4 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3328 PF11807.3 EIW83163.1 - 0.17 11.5 1.0 1.1 8.9 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3328) DUF1761 PF08570.5 EIW83163.1 - 0.86 9.6 12.7 0.063 13.2 1.0 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1761) OAD_gamma PF04277.8 EIW83163.1 - 0.93 9.9 0.0 0.93 9.9 0.0 3.0 5 0 0 5 5 5 0 Oxaloacetate decarboxylase, gamma chain DUF2500 PF10694.4 EIW83163.1 - 2.7 8.0 0.0 2.7 8.0 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2500) Tcp11 PF05794.8 EIW83164.1 - 3e-13 49.2 0.0 4e-12 45.5 0.0 2.4 1 1 0 1 1 1 1 T-complex protein 11 Ssl1 PF04056.9 EIW83165.1 - 8.7e-71 237.5 0.0 1.1e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like VWA_2 PF13519.1 EIW83165.1 - 3.9e-11 43.3 0.0 5.9e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Tfb4 PF03850.9 EIW83165.1 - 0.0064 15.7 4.7 1.3 8.2 0.0 2.3 2 0 0 2 2 2 2 Transcription factor Tfb4 DUF4428 PF14471.1 EIW83165.1 - 0.38 10.5 3.7 2.1 8.1 2.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) C5-epim_C PF06662.8 EIW83166.1 - 0.093 12.0 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus DUF3592 PF12158.3 EIW83166.1 - 0.12 12.1 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) EB PF01683.13 EIW83166.1 - 9.4 6.3 35.9 0.77 9.8 2.3 4.4 4 1 0 4 4 4 0 EB module Na_H_Exchanger PF00999.16 EIW83167.1 - 1.4e-73 247.6 56.2 8.7e-52 175.9 17.4 4.0 2 1 0 2 2 2 2 Sodium/hydrogen exchanger family FUN14 PF04930.10 EIW83167.1 - 0.061 13.6 2.9 14 6.0 0.1 3.4 2 0 0 2 2 2 0 FUN14 family DUF543 PF04418.7 EIW83167.1 - 0.2 11.6 5.3 0.49 10.3 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF543) SGL PF08450.7 EIW83168.1 - 2e-05 24.0 0.0 4.6e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EIW83168.1 - 0.00011 22.0 0.0 0.00024 21.0 0.0 1.5 1 0 0 1 1 1 1 Arylesterase mIF3 PF14877.1 EIW83168.1 - 0.073 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial translation initiation factor Peptidase_C1_2 PF03051.10 EIW83169.1 - 1.3e-153 511.6 0.0 1.6e-153 511.4 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EIW83169.1 - 2.1e-07 31.0 0.0 0.02 14.7 0.0 2.3 2 0 0 2 2 2 2 Papain family cysteine protease Phage_portal_2 PF05136.8 EIW83169.1 - 0.04 12.4 0.0 0.061 11.8 0.0 1.2 1 0 0 1 1 1 0 Phage portal protein, lambda family E3_binding PF02817.12 EIW83170.1 - 0.13 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 e3 binding domain Pam16 PF03656.8 EIW83173.1 - 8.2e-23 80.5 0.1 1e-14 54.4 0.1 2.2 2 0 0 2 2 2 2 Pam16 SHS2_Rpb7-N PF03876.12 EIW83174.1 - 1.6e-07 31.3 0.0 6.4e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 GATase PF00117.23 EIW83175.1 - 0.0023 17.4 0.0 0.019 14.4 0.0 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I FliG_N PF14842.1 EIW83175.1 - 0.05 13.7 0.0 0.086 12.9 0.0 1.3 1 0 0 1 1 1 0 FliG N-terminal domain APH PF01636.18 EIW83176.1 - 2e-11 44.0 0.0 2.3e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIW83176.1 - 0.029 13.9 0.0 0.035 13.6 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase SH3_2 PF07653.12 EIW83177.1 - 0.072 12.5 0.5 2.6 7.5 0.1 2.6 2 1 0 2 2 2 0 Variant SH3 domain SNF2_N PF00176.18 EIW83178.1 - 6.8e-68 228.6 0.5 6.8e-68 228.6 0.4 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF4208 PF13907.1 EIW83178.1 - 3.8e-26 91.2 2.6 5.5e-26 90.7 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) Chromo PF00385.19 EIW83178.1 - 3e-19 68.4 2.6 1.6e-14 53.3 0.2 3.1 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EIW83178.1 - 3.2e-14 52.5 0.0 7.8e-14 51.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW83178.1 - 2.2e-07 30.9 1.9 2.2e-06 27.6 0.0 3.2 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EIW83178.1 - 0.00062 19.2 0.1 0.0022 17.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase TBP PF00352.16 EIW83178.1 - 0.0055 16.0 0.0 0.018 14.4 0.0 1.8 1 0 0 1 1 1 1 Transcription factor TFIID (or TATA-binding protein, TBP) AAA_22 PF13401.1 EIW83178.1 - 0.0056 16.8 0.6 0.059 13.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain FlhC PF05280.6 EIW83178.1 - 0.047 13.1 0.4 0.13 11.6 0.1 1.9 2 0 0 2 2 2 0 Flagellar transcriptional activator (FlhC) DUF1771 PF08590.5 EIW83179.1 - 0.0059 16.5 2.7 0.013 15.5 1.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Slu7 PF11708.3 EIW83180.1 - 1.1e-80 270.8 12.9 1.1e-80 270.8 8.9 2.6 2 1 1 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EIW83180.1 - 0.047 13.3 0.7 0.095 12.3 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF3128 PF11326.3 EIW83180.1 - 3.5 7.8 6.5 0.31 11.1 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3128) RNase_H2-Ydr279 PF09468.5 EIW83182.1 - 3.6e-53 180.7 0.0 4.4e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) ATP-sulfurylase PF01747.12 EIW83183.1 - 1.6e-86 289.1 0.2 2.3e-86 288.5 0.2 1.2 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.1 EIW83183.1 - 9.2e-53 177.9 0.0 1.5e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain APS_kinase PF01583.15 EIW83183.1 - 6.7e-40 136.3 0.0 1e-39 135.7 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase KTI12 PF08433.5 EIW83183.1 - 0.0014 17.9 0.0 0.0025 17.0 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Torsin PF06309.6 EIW83183.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Torsin MmgE_PrpD PF03972.9 EIW83185.1 - 5.5e-159 529.0 0.0 6.6e-159 528.8 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family Chitin_synth_2 PF03142.10 EIW83186.1 - 1.3e-229 763.0 0.0 1.7e-229 762.6 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EIW83186.1 - 4.7e-115 385.2 0.0 7.2e-115 384.5 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EIW83186.1 - 3.2e-18 65.3 0.0 1.4e-11 44.0 0.0 2.7 1 1 1 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_trans_2_3 PF13632.1 EIW83186.1 - 3.3e-16 59.5 2.8 3.3e-16 59.5 2.0 2.0 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIW83186.1 - 5.5e-16 59.0 0.0 2.9e-11 43.6 0.0 2.4 2 0 0 2 2 2 2 Glycosyltransferase like family 2 DEK_C PF08766.6 EIW83186.1 - 1.1e-13 50.7 0.2 3.8e-13 48.9 0.1 2.0 2 0 0 2 2 2 1 DEK C terminal domain Glycos_transf_2 PF00535.21 EIW83186.1 - 2.4e-08 33.8 0.0 3.5e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIW83186.1 - 0.00016 21.0 0.0 0.0039 16.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 AAA_16 PF13191.1 EIW83186.1 - 0.0084 16.1 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Use1 PF09753.4 EIW83187.1 - 5.9e-17 61.9 1.0 9.2e-17 61.3 0.7 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 Tmemb_cc2 PF10267.4 EIW83187.1 - 0.012 14.1 0.3 0.012 14.1 0.2 1.9 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein Phage_GPO PF05929.6 EIW83187.1 - 0.077 12.2 1.2 0.12 11.5 0.9 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2450 PF10475.4 EIW83187.1 - 0.21 10.4 2.5 0.17 10.7 0.5 1.6 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) EMP24_GP25L PF01105.19 EIW83187.1 - 0.33 10.6 2.1 0.28 10.8 0.3 1.6 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD WXG100 PF06013.7 EIW83187.1 - 1.1 9.2 4.3 24 5.0 0.3 3.1 3 1 1 4 4 4 0 Proteins of 100 residues with WXG MMR_HSR1 PF01926.18 EIW83188.1 - 1.3e-13 50.8 0.0 4.3e-11 42.7 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 EIW83188.1 - 4.5e-09 35.7 0.0 9.5e-08 31.4 0.0 2.1 2 0 0 2 2 2 1 AIG1 family DUF258 PF03193.11 EIW83188.1 - 8.8e-06 24.9 0.0 2.2e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Ras PF00071.17 EIW83188.1 - 0.00011 21.5 0.0 0.00025 20.4 0.0 1.6 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW83188.1 - 0.00045 20.7 0.0 0.0018 18.7 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein ABC_tran PF00005.22 EIW83188.1 - 0.0011 19.2 0.0 0.0023 18.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_10 PF12846.2 EIW83188.1 - 0.002 17.5 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain DUF87 PF01935.12 EIW83188.1 - 0.0022 17.8 0.5 0.02 14.7 0.1 2.3 3 0 0 3 3 3 1 Domain of unknown function DUF87 AHH PF14412.1 EIW83188.1 - 0.0035 17.3 0.1 0.45 10.5 0.0 2.4 2 0 0 2 2 2 1 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH Dynamin_N PF00350.18 EIW83188.1 - 0.016 15.0 0.9 0.082 12.7 0.4 2.3 2 1 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.13 EIW83188.1 - 0.019 14.4 0.0 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family IIGP PF05049.8 EIW83188.1 - 0.034 12.9 0.0 0.065 12.0 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.1 EIW83188.1 - 0.063 13.2 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF815 PF05673.8 EIW83188.1 - 0.071 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.1 EIW83188.1 - 0.088 12.9 0.0 0.3 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EIW83188.1 - 0.096 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain FeoB_N PF02421.13 EIW83188.1 - 0.1 11.8 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B RNA_helicase PF00910.17 EIW83188.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 EIW83188.1 - 0.13 11.7 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 EIW83188.1 - 0.14 11.1 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 Septin MMR_HSR1 PF01926.18 EIW83189.1 - 1.7e-09 37.6 0.0 3.9e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIW83189.1 - 3.1e-07 30.8 0.0 9.8e-07 29.2 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 EIW83189.1 - 3.8e-05 22.9 0.0 6.8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EIW83189.1 - 0.00023 20.3 0.0 0.00064 18.8 0.0 1.7 2 0 0 2 2 2 1 AIG1 family Ras PF00071.17 EIW83189.1 - 0.0013 18.1 0.1 0.0027 17.1 0.0 1.5 1 0 0 1 1 1 1 Ras family AAA_16 PF13191.1 EIW83189.1 - 0.002 18.1 0.4 0.06 13.3 0.0 3.0 4 1 0 4 4 4 1 AAA ATPase domain ABC_tran PF00005.22 EIW83189.1 - 0.0022 18.3 0.1 0.0076 16.5 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_10 PF12846.2 EIW83189.1 - 0.0027 17.1 0.1 0.0067 15.9 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain Dynamin_N PF00350.18 EIW83189.1 - 0.0071 16.1 1.1 0.013 15.2 0.2 1.9 2 0 0 2 2 2 1 Dynamin family IIGP PF05049.8 EIW83189.1 - 0.016 14.0 0.1 0.025 13.4 0.1 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.13 EIW83189.1 - 0.025 13.8 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.1 EIW83189.1 - 0.031 14.4 0.1 0.094 12.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIW83189.1 - 0.067 12.7 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 EIW83189.1 - 0.069 12.1 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_17 PF13207.1 EIW83189.1 - 0.076 13.8 0.1 0.33 11.7 0.1 2.4 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 EIW83189.1 - 0.083 11.8 0.5 0.22 10.4 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EIW83189.1 - 0.16 12.1 0.4 0.48 10.6 0.0 1.9 2 0 0 2 2 2 0 RNA helicase Pyr_redox_3 PF13738.1 EIW83191.1 - 5.6e-25 88.5 0.0 1e-24 87.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIW83191.1 - 3.5e-19 68.3 0.0 2.4e-18 65.6 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EIW83191.1 - 4.5e-12 45.5 0.5 2.3e-08 33.3 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EIW83191.1 - 1.5e-10 41.3 0.4 2.9e-05 24.3 0.1 3.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW83191.1 - 1.3e-09 38.2 0.0 3.9e-09 36.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW83191.1 - 2.9e-05 23.1 0.0 0.029 13.2 0.0 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW83191.1 - 6.4e-05 22.8 0.0 0.00041 20.3 0.0 2.4 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EIW83191.1 - 0.00058 19.0 0.2 0.87 8.5 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EIW83191.1 - 0.00087 19.0 1.3 0.38 10.5 0.0 2.9 2 1 1 3 3 3 2 FAD-NAD(P)-binding HI0933_like PF03486.9 EIW83191.1 - 0.00095 17.7 0.0 0.14 10.5 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein 3HCDH_N PF02737.13 EIW83191.1 - 0.0016 18.1 0.1 0.077 12.6 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EIW83191.1 - 0.0021 17.2 0.3 0.0056 15.7 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.14 EIW83191.1 - 0.028 13.5 0.0 0.26 10.4 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EIW83191.1 - 0.034 13.0 0.0 0.15 10.9 0.0 1.9 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EIW83191.1 - 0.047 12.5 0.1 0.094 11.5 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 EIW83191.1 - 0.099 12.6 0.2 0.25 11.3 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain GIDA PF01134.17 EIW83191.1 - 0.16 10.7 0.4 0.55 9.0 0.2 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Methyltransf_31 PF13847.1 EIW83193.1 - 1.7e-14 53.6 0.2 2.5e-14 53.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EIW83193.1 - 4.3e-12 45.7 0.1 7e-12 45.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EIW83193.1 - 3.8e-11 43.5 0.0 9.9e-11 42.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW83193.1 - 1.7e-10 41.2 0.0 4e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW83193.1 - 1.3e-09 38.0 0.0 7.9e-09 35.5 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain CMAS PF02353.15 EIW83193.1 - 1.2e-08 34.3 0.1 1.8e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EIW83193.1 - 1.3e-07 31.1 0.1 2.2e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EIW83193.1 - 1.3e-07 31.4 0.0 3e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EIW83193.1 - 4e-07 29.3 0.0 5.9e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_9 PF08003.6 EIW83193.1 - 4.1e-07 29.0 0.0 6e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 EIW83193.1 - 4.7e-07 30.1 0.0 9.1e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW83193.1 - 1.3e-06 28.7 0.0 2.8e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIW83193.1 - 0.00021 20.8 0.1 0.00041 19.9 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 EIW83193.1 - 0.00023 21.2 0.0 0.00042 20.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EIW83193.1 - 0.00031 19.9 0.1 0.00049 19.2 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EIW83193.1 - 0.00045 19.7 0.1 0.0008 18.9 0.1 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_32 PF13679.1 EIW83193.1 - 0.00088 18.9 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EIW83193.1 - 0.0011 18.1 0.2 0.0032 16.6 0.2 1.8 1 1 0 1 1 1 1 Tellurite resistance protein TehB UPF0020 PF01170.13 EIW83193.1 - 0.0012 18.4 0.1 0.0023 17.5 0.1 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_24 PF13578.1 EIW83193.1 - 0.0067 17.2 0.0 0.016 16.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EIW83193.1 - 0.023 14.2 0.0 0.037 13.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Cons_hypoth95 PF03602.10 EIW83193.1 - 0.044 13.1 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_4 PF02390.12 EIW83193.1 - 0.1 11.6 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Putative methyltransferase DUF2367 PF10164.4 EIW83194.1 - 4.3e-06 26.4 1.1 9.5e-06 25.3 0.8 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2367) Myb_Cef PF11831.3 EIW83195.1 - 3.1e-57 193.4 0.3 3.1e-57 193.4 0.2 3.9 5 0 0 5 5 5 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EIW83195.1 - 1.3e-20 73.1 5.7 8.2e-11 41.7 0.4 2.9 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIW83195.1 - 1.6e-17 63.3 7.8 3e-12 46.4 2.2 3.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain UvdE PF03851.9 EIW83196.1 - 9.4e-88 293.8 0.0 1.4e-87 293.2 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF3863 PF12979.2 EIW83196.1 - 0.21 10.1 0.0 0.35 9.4 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) BAR PF03114.13 EIW83197.1 - 1.6e-47 161.9 1.0 1.9e-47 161.7 0.7 1.1 1 0 0 1 1 1 1 BAR domain AAA_13 PF13166.1 EIW83197.1 - 0.01 14.3 0.2 0.017 13.6 0.2 1.3 1 0 0 1 1 1 0 AAA domain Arfaptin PF06456.8 EIW83197.1 - 0.027 13.8 1.2 0.063 12.6 0.8 1.8 1 1 0 1 1 1 0 Arfaptin-like domain SYF2 PF08231.7 EIW83197.1 - 0.36 10.9 4.0 0.34 11.0 1.2 2.0 2 1 0 2 2 2 0 SYF2 splicing factor RHD3 PF05879.7 EIW83198.1 - 1.4e-248 826.6 5.6 1.3e-247 823.4 3.9 1.9 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EIW83198.1 - 4.4e-07 29.2 0.1 9.8e-07 28.0 0.1 1.6 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Miro PF08477.8 EIW83198.1 - 7e-06 26.5 0.1 1.6e-05 25.3 0.1 1.6 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EIW83198.1 - 2.1e-05 24.4 0.0 4.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EIW83198.1 - 2.3e-05 24.3 0.1 9.1e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.1 EIW83198.1 - 0.0021 18.0 0.8 0.0052 16.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain YqbF PF14553.1 EIW83198.1 - 0.049 13.3 0.6 0.12 12.0 0.4 1.7 1 0 0 1 1 1 0 YqbF, hypothetical protein domain Septin PF00735.13 EIW83198.1 - 0.087 11.8 0.1 0.17 10.8 0.1 1.4 1 0 0 1 1 1 0 Septin AMP-binding PF00501.23 EIW83199.1 - 7.9e-45 152.9 0.0 1.1e-44 152.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIW83199.1 - 0.0011 19.9 0.0 0.004 18.0 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Lac_bphage_repr PF06543.7 EIW83199.1 - 0.085 12.3 0.1 2.6 7.6 0.0 2.7 3 0 0 3 3 3 0 Lactococcus bacteriophage repressor Gemin7 PF11095.3 EIW83200.1 - 0.032 13.9 0.1 0.063 13.0 0.0 1.5 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) DEAD PF00270.24 EIW83201.1 - 7.8e-13 48.2 0.0 1.6e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW83201.1 - 4.6e-10 39.2 0.0 1.2e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW83201.1 - 0.0031 17.3 0.0 0.0069 16.2 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Glutaredoxin PF00462.19 EIW83202.1 - 1.4e-10 40.9 0.0 2.1e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 EIW83202.1 - 0.00046 20.3 0.0 0.00067 19.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW83202.1 - 0.088 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GKAP PF03359.8 EIW83203.1 - 5.7 6.4 10.2 16 4.9 7.2 1.6 1 1 1 2 2 2 0 Guanylate-kinase-associated protein (GKAP) protein Aldo_ket_red PF00248.16 EIW83204.1 - 2e-63 213.8 0.1 2.3e-63 213.6 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FR47 PF08445.5 EIW83205.1 - 1.4e-07 31.1 0.0 2.7e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 EIW83205.1 - 0.00011 22.1 0.0 0.00023 21.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EIW83205.1 - 0.00045 20.3 0.0 0.00082 19.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.5 EIW83205.1 - 0.025 14.6 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Acetyltransf_7 PF13508.1 EIW83205.1 - 0.031 14.4 0.0 0.056 13.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIW83206.1 - 0.0016 18.1 0.1 0.0066 16.1 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 EIW83206.1 - 0.021 14.9 0.0 0.058 13.5 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW83206.1 - 0.049 13.6 0.0 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family SNARE PF05739.14 EIW83207.1 - 2.1e-16 59.3 1.4 2.1e-16 59.3 1.0 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EIW83207.1 - 4.8e-14 52.3 0.6 5e-11 42.6 0.0 2.4 2 0 0 2 2 2 2 Syntaxin Syntaxin_2 PF14523.1 EIW83207.1 - 0.0083 16.1 4.6 0.33 10.9 0.2 2.4 2 0 0 2 2 2 2 Syntaxin-like protein TMEM154 PF15102.1 EIW83207.1 - 0.027 14.1 0.1 0.063 12.9 0.1 1.7 1 1 0 1 1 1 0 TMEM154 protein family Lebercilin PF15619.1 EIW83207.1 - 0.042 13.2 4.1 0.47 9.8 0.2 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Fe_hyd_lg_C PF02906.9 EIW83209.1 - 7.4e-65 219.0 0.0 1.1e-64 218.4 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain DAO PF01266.19 EIW83210.1 - 2.3e-50 171.5 9.8 8.2e-50 169.7 6.8 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.14 EIW83210.1 - 3.5e-07 29.6 0.0 0.0012 18.0 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase Trp_halogenase PF04820.9 EIW83210.1 - 8.4e-06 24.6 0.3 0.0079 14.8 0.5 2.1 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 EIW83210.1 - 2.8e-05 24.0 0.2 6.8e-05 22.8 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIW83210.1 - 0.00014 21.8 0.4 0.64 9.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW83210.1 - 0.00021 20.2 2.8 0.0063 15.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EIW83210.1 - 0.0014 17.7 0.8 0.15 11.1 0.3 2.2 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 EIW83210.1 - 0.0019 18.5 0.5 0.0043 17.4 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIW83210.1 - 0.0075 15.3 0.7 0.58 9.1 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EIW83210.1 - 0.0077 16.0 1.1 0.21 11.3 0.1 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Saccharop_dh PF03435.13 EIW83210.1 - 0.0091 15.0 0.5 0.017 14.1 0.3 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase GIDA PF01134.17 EIW83210.1 - 0.066 12.0 2.3 2.2 7.0 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A DUF605 PF04652.11 EIW83212.1 - 4.9 6.4 7.1 5.3 6.3 4.9 1.1 1 0 0 1 1 1 0 Vta1 like Aa_trans PF01490.13 EIW83213.1 - 8.1e-73 245.2 23.2 9.5e-73 245.0 16.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EIW83213.1 - 8.8e-05 21.4 11.6 8.8e-05 21.4 8.0 2.3 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family GHMP_kinases_N PF00288.21 EIW83214.1 - 2.4e-10 40.3 2.6 2.4e-10 40.3 1.8 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EIW83214.1 - 1e-07 32.0 0.0 4e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 GHMP kinases C terminal Ferrochelatase PF00762.14 EIW83215.1 - 3.2e-95 318.7 0.0 3.6e-95 318.5 0.0 1.0 1 0 0 1 1 1 1 Ferrochelatase DUF3533 PF12051.3 EIW83216.1 - 3e-71 240.2 15.0 5.8e-71 239.2 10.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3533) DUF4282 PF14110.1 EIW83216.1 - 1.9 8.7 15.9 1.2 9.3 2.7 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4282) zf-RING_2 PF13639.1 EIW83217.1 - 2.3e-10 40.1 8.9 7.5e-10 38.4 0.3 2.7 3 0 0 3 3 2 2 Ring finger domain zf-rbx1 PF12678.2 EIW83217.1 - 5.5e-09 36.0 0.2 1.2e-06 28.5 0.0 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EIW83217.1 - 3e-07 30.3 0.3 3e-07 30.3 0.2 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW83217.1 - 6.4e-07 28.9 2.3 5.3e-05 22.7 0.0 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW83217.1 - 4.3e-06 26.3 0.7 1.6e-05 24.5 0.1 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EIW83217.1 - 0.0001 22.0 0.2 0.00072 19.3 0.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EIW83217.1 - 0.00018 21.1 0.2 0.00018 21.1 0.1 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EIW83217.1 - 0.0015 18.0 0.6 0.0032 16.9 0.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 EIW83217.1 - 0.02 14.6 0.5 0.02 14.6 0.3 2.3 2 1 1 3 3 3 0 RING-type zinc-finger zf-Nse PF11789.3 EIW83217.1 - 0.021 14.3 0.3 0.13 11.7 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Rad50_zn_hook PF04423.9 EIW83217.1 - 0.028 13.8 0.5 0.061 12.8 0.3 1.5 1 0 0 1 1 1 0 Rad50 zinc hook motif zf-RING_6 PF14835.1 EIW83217.1 - 0.029 14.1 0.1 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING-like PF08746.6 EIW83217.1 - 0.038 13.9 0.9 0.09 12.7 0.6 1.6 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.1 EIW83217.1 - 0.046 13.6 7.8 0.059 13.2 0.3 3.3 3 0 0 3 3 3 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EIW83217.1 - 0.19 11.7 4.1 0.63 10.0 1.3 2.7 2 1 0 2 2 2 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EIW83217.1 - 0.3 10.7 2.1 0.24 11.0 0.2 1.8 2 0 0 2 2 1 0 RING/Ubox like zinc-binding domain HAD_2 PF13419.1 EIW83218.1 - 5.9e-14 52.6 0.0 6.9e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIW83218.1 - 4.9e-09 35.7 0.0 8.4e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EIW83218.1 - 7e-06 26.5 0.0 8.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosomal_S6 PF01250.12 EIW83219.1 - 2.2e-09 37.0 0.0 2.6e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 ABC_tran PF00005.22 EIW83220.1 - 7.3e-48 162.3 0.0 3.6e-27 95.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIW83220.1 - 1.6e-43 149.0 15.6 1.9e-22 80.0 6.7 2.9 2 1 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EIW83220.1 - 8.4e-08 31.7 5.6 0.004 16.4 0.2 3.8 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EIW83220.1 - 3.5e-07 29.8 0.1 0.0036 16.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EIW83220.1 - 5.3e-05 22.6 0.5 0.12 11.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EIW83220.1 - 0.00025 21.1 0.1 2.5 7.9 0.0 3.3 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EIW83220.1 - 0.0003 20.3 0.0 0.55 9.6 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.1 EIW83220.1 - 0.0011 18.9 0.6 0.038 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EIW83220.1 - 0.0024 18.0 0.3 1.5 8.9 0.1 3.3 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EIW83220.1 - 0.0028 17.1 0.2 0.44 9.9 0.0 2.8 3 0 0 3 3 3 1 AAA-like domain T2SE PF00437.15 EIW83220.1 - 0.013 14.4 0.0 0.53 9.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein KaiC PF06745.8 EIW83220.1 - 0.032 13.3 0.1 5.4 6.0 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_23 PF13476.1 EIW83220.1 - 0.036 14.4 0.0 9.9 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EIW83220.1 - 0.036 13.2 0.0 1.8 7.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 DUF87 PF01935.12 EIW83220.1 - 0.068 12.9 0.2 0.068 12.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF87 Oxidored_FMN PF00724.15 EIW83221.1 - 2.8e-28 98.8 0.0 8.7e-25 87.4 0.0 3.2 3 1 0 3 3 3 3 NADH:flavin oxidoreductase / NADH oxidase family Trypan_PARP PF05887.6 EIW83222.1 - 4.3e-05 23.3 27.7 4.3e-05 23.3 19.2 6.8 4 3 1 5 5 5 1 Procyclic acidic repetitive protein (PARP) Podoplanin PF05808.6 EIW83224.1 - 0.0031 17.0 7.6 0.0068 15.9 5.3 1.6 1 0 0 1 1 1 1 Podoplanin Syndecan PF01034.15 EIW83224.1 - 0.0056 16.3 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain DUF1129 PF06570.6 EIW83226.1 - 0.03 13.6 5.0 0.072 12.3 3.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Zip PF02535.17 EIW83226.1 - 8.1 5.3 12.5 0.86 8.5 4.3 2.5 3 1 0 4 4 4 0 ZIP Zinc transporter F-box-like PF12937.2 EIW83227.1 - 1.2e-09 37.6 2.5 3.2e-09 36.3 1.7 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIW83227.1 - 0.0017 17.9 1.3 4.4 7.0 0.0 4.9 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) F-box-like_2 PF13013.1 EIW83227.1 - 0.011 15.4 2.0 0.015 15.0 0.5 1.9 2 0 0 2 2 2 0 F-box-like domain DEAD PF00270.24 EIW83227.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 DEAD/DEAH box helicase LRR_6 PF13516.1 EIW83227.1 - 0.19 11.9 1.9 71 3.9 0.2 5.0 6 0 0 6 6 6 0 Leucine Rich repeat bZIP_2 PF07716.10 EIW83228.1 - 6e-12 45.1 16.2 8.3e-11 41.5 5.4 2.6 2 0 0 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 EIW83228.1 - 6.9e-11 41.9 11.4 1.1e-09 38.0 4.3 2.5 2 0 0 2 2 2 2 bZIP transcription factor bZIP_Maf PF03131.12 EIW83228.1 - 0.0033 17.6 3.9 0.0033 17.6 2.7 2.7 3 0 0 3 3 3 1 bZIP Maf transcription factor HALZ PF02183.13 EIW83228.1 - 0.017 14.7 0.2 4.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper Fmp27_WPPW PF10359.4 EIW83228.1 - 0.064 11.6 0.3 0.087 11.2 0.2 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain HAP1_N PF04849.8 EIW83228.1 - 0.15 11.0 4.1 0.075 11.9 0.3 1.9 2 0 0 2 2 2 0 HAP1 N-terminal conserved region DivIC PF04977.10 EIW83228.1 - 1.1 8.8 4.9 7.3 6.1 1.0 2.3 2 0 0 2 2 2 0 Septum formation initiator Sigma70_ner PF04546.8 EIW83228.1 - 2.7 7.5 7.3 19 4.7 5.1 2.0 1 1 0 1 1 1 0 Sigma-70, non-essential region F-box-like PF12937.2 EIW83229.1 - 4.3e-05 23.1 0.1 0.00016 21.3 0.1 2.1 1 0 0 1 1 1 1 F-box-like DUF1091 PF06477.8 EIW83229.1 - 0.016 15.6 0.1 2.6 8.5 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1091) CHZ PF09649.5 EIW83231.1 - 4.5e-07 28.9 0.2 4.5e-07 28.9 0.1 3.0 3 1 0 3 3 1 1 Histone chaperone domain CHZ Prothymosin PF03247.9 EIW83231.1 - 0.012 15.7 20.9 0.012 15.7 14.5 2.1 2 0 0 2 2 2 0 Prothymosin/parathymosin family DDHD PF02862.12 EIW83231.1 - 0.11 12.2 3.8 0.12 12.1 2.7 1.1 1 0 0 1 1 1 0 DDHD domain Nucleoplasmin PF03066.10 EIW83231.1 - 0.22 11.0 21.5 0.065 12.7 10.5 2.1 2 0 0 2 2 2 0 Nucleoplasmin Spore_coat_CotO PF14153.1 EIW83231.1 - 0.28 10.5 6.3 0.28 10.6 4.4 1.2 1 0 0 1 1 1 0 Spore coat protein CotO FAM176 PF14851.1 EIW83231.1 - 0.31 10.7 13.9 0.025 14.2 6.5 1.5 1 1 1 2 2 2 0 FAM176 family SpoIIIAH PF12685.2 EIW83231.1 - 0.39 10.1 7.9 0.46 9.9 5.5 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Tim54 PF11711.3 EIW83231.1 - 0.69 8.4 5.4 0.7 8.4 3.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Retinal PF15449.1 EIW83231.1 - 0.82 7.2 7.9 0.89 7.1 5.5 1.1 1 0 0 1 1 1 0 Retinal protein TEX19 PF15553.1 EIW83231.1 - 1 9.2 9.0 1.2 9.0 6.2 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 CDC27 PF09507.5 EIW83231.1 - 1.2 8.2 17.0 1.3 8.1 11.8 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF740 PF05340.7 EIW83231.1 - 1.8 6.8 7.7 1.7 6.8 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) AF1Q PF15017.1 EIW83231.1 - 1.9 8.4 15.4 0.25 11.2 6.8 2.1 2 0 0 2 2 2 0 Drug resistance and apoptosis regulator Zip PF02535.17 EIW83231.1 - 2.3 7.1 3.9 2.8 6.8 2.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter VID27 PF08553.5 EIW83231.1 - 2.5 6.2 11.0 2.2 6.4 7.6 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein SDA1 PF05285.7 EIW83231.1 - 2.7 7.1 18.1 3.1 7.0 12.5 1.1 1 0 0 1 1 1 0 SDA1 TraH_2 PF06871.6 EIW83231.1 - 3.3 7.1 6.4 4.9 6.5 4.4 1.2 1 0 0 1 1 1 0 TraH_2 BUD22 PF09073.5 EIW83231.1 - 5.8 5.8 18.7 7.3 5.5 13.0 1.2 1 0 0 1 1 1 0 BUD22 RRN3 PF05327.6 EIW83231.1 - 7.9 4.4 9.8 7.8 4.4 6.8 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 AFG1_ATPase PF03969.11 EIW83233.1 - 3.6e-56 190.5 0.0 4.1e-51 173.9 0.0 2.7 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EIW83233.1 - 1.7e-05 24.9 0.0 9.4e-05 22.4 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW83233.1 - 5.5e-05 23.3 0.0 0.00019 21.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EIW83233.1 - 0.0067 15.9 0.0 0.019 14.3 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain AAA_29 PF13555.1 EIW83233.1 - 0.0097 15.4 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_19 PF13245.1 EIW83233.1 - 0.019 14.7 0.0 0.048 13.4 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 EIW83233.1 - 0.037 13.1 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EIW83233.1 - 0.038 13.4 0.1 0.3 10.4 0.0 2.4 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_33 PF13671.1 EIW83233.1 - 0.053 13.3 0.1 0.17 11.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EIW83233.1 - 0.088 13.0 0.0 0.58 10.3 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EIW83233.1 - 0.1 11.7 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin T2SE PF00437.15 EIW83233.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_5 PF07728.9 EIW83233.1 - 0.12 12.0 0.0 0.36 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) TMCO5 PF14992.1 EIW83234.1 - 9.2 5.3 6.4 13 4.8 4.4 1.2 1 0 0 1 1 1 0 TMCO5 family TFIID_20kDa PF03847.8 EIW83235.1 - 3e-25 88.2 0.0 3.5e-25 88.0 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 EIW83235.1 - 0.00012 22.0 0.0 0.00014 21.8 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-18kDa PF02269.11 EIW83235.1 - 0.082 12.7 0.0 0.09 12.5 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit PDZ_2 PF13180.1 EIW83235.1 - 0.083 12.7 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 PDZ domain Histone PF00125.19 EIW83235.1 - 0.1 12.7 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 HlyIII PF03006.15 EIW83236.1 - 3.2e-39 134.6 16.6 4.3e-39 134.2 11.5 1.2 1 0 0 1 1 1 1 Haemolysin-III related zf-GRF PF06839.7 EIW83236.1 - 0.19 11.6 2.4 0.35 10.8 1.6 1.4 1 0 0 1 1 1 0 GRF zinc finger EmrE PF13536.1 EIW83236.1 - 6.6 6.9 12.3 0.24 11.6 2.9 2.5 2 1 0 2 2 2 0 Multidrug resistance efflux transporter Abhydrolase_3 PF07859.8 EIW83237.1 - 1.7e-07 31.0 0.0 1.5e-06 27.9 0.0 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIW83237.1 - 0.1 11.2 0.0 0.37 9.3 0.0 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2424) DOCK-C2 PF14429.1 EIW83239.1 - 5.6e-39 133.6 0.0 1e-38 132.8 0.0 1.5 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EIW83239.1 - 1.5e-34 118.8 0.0 3.6e-34 117.5 0.0 1.7 1 0 0 1 1 1 1 Dedicator of cytokinesis Med27 PF11571.3 EIW83241.1 - 4.4e-07 29.9 1.2 9.8e-07 28.8 0.3 2.0 2 1 0 2 2 2 1 Mediator complex subunit 27 Cytochrome-c551 PF10643.4 EIW83241.1 - 0.045 13.0 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 LETM1 PF07766.8 EIW83242.1 - 2.5e-21 75.9 0.1 2.6e-10 39.8 0.0 2.1 1 1 1 2 2 2 2 LETM1-like protein F-box-like PF12937.2 EIW83243.1 - 1.9e-07 30.7 0.7 6.3e-07 29.0 0.5 1.9 1 0 0 1 1 1 1 F-box-like DUF4140 PF13600.1 EIW83243.1 - 0.011 16.1 0.3 0.037 14.4 0.2 1.8 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) CENP-Q PF13094.1 EIW83243.1 - 0.058 13.4 4.1 0.068 13.1 2.0 1.6 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit F-box-like_2 PF13013.1 EIW83243.1 - 0.066 12.9 1.5 0.39 10.4 0.5 2.6 2 1 0 2 2 2 0 F-box-like domain F-box PF00646.28 EIW83243.1 - 0.068 12.8 1.7 0.38 10.4 1.2 2.2 1 1 0 1 1 1 0 F-box domain Spc7 PF08317.6 EIW83243.1 - 0.19 10.3 1.3 0.36 9.4 0.9 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Glyco_hydro_16 PF00722.16 EIW83244.1 - 6.2e-09 35.3 0.0 1.4e-08 34.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_12 PF01670.11 EIW83245.1 - 9.6e-35 119.6 3.5 9.6e-35 119.6 2.4 1.9 1 1 1 2 2 2 1 Glycosyl hydrolase family 12 DUF402 PF04167.8 EIW83245.1 - 0.0081 15.9 0.7 1 9.2 0.2 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF402) PLA2_B PF01735.13 EIW83246.1 - 8.3e-103 344.1 4.3 3.8e-100 335.3 1.1 2.1 2 0 0 2 2 2 2 Lysophospholipase catalytic domain bZIP_1 PF00170.16 EIW83247.1 - 3.9e-06 26.7 17.6 3.8e-05 23.5 6.9 3.0 2 1 1 3 3 3 2 bZIP transcription factor FlgN PF05130.7 EIW83247.1 - 0.64 10.2 7.3 0.93 9.7 5.1 1.3 1 0 0 1 1 1 0 FlgN protein PAT1 PF09770.4 EIW83247.1 - 6 4.9 44.3 6.9 4.7 30.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PTPLA PF04387.9 EIW83248.1 - 5.7e-51 172.2 8.4 1.6e-50 170.7 5.8 1.8 1 1 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DASH_Spc34 PF08657.5 EIW83249.1 - 8e-07 28.9 0.9 0.0054 16.4 0.0 2.9 2 1 0 2 2 2 2 DASH complex subunit Spc34 HR1 PF02185.11 EIW83249.1 - 0.2 11.4 4.0 1 9.1 2.7 2.0 1 1 1 2 2 2 0 Hr1 repeat AKNA PF12443.3 EIW83249.1 - 0.86 9.6 4.9 0.67 9.9 0.3 2.4 2 0 0 2 2 2 0 AT-hook-containing transcription factor F-box PF00646.28 EIW83250.1 - 1.6e-06 27.6 0.1 3.4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW83250.1 - 1.5e-05 24.6 0.4 3.5e-05 23.4 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW83251.1 - 1.8e-05 24.2 0.0 4.4e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW83251.1 - 0.00054 19.6 0.1 0.0016 18.0 0.1 1.9 1 0 0 1 1 1 1 F-box-like DPM3 PF08285.6 EIW83253.1 - 0.47 10.3 3.2 0.59 10.0 0.4 2.1 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DSPc PF00782.15 EIW83254.1 - 0.0001 21.9 0.4 0.00031 20.3 0.1 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.7 EIW83254.1 - 0.011 15.2 0.3 0.02 14.3 0.2 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF442 PF04273.8 EIW83254.1 - 0.031 14.1 0.0 0.1 12.4 0.0 1.8 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Y_phosphatase PF00102.22 EIW83254.1 - 0.055 12.8 1.9 0.16 11.3 1.3 1.7 1 1 0 1 1 1 0 Protein-tyrosine phosphatase Chitin_synth_2 PF03142.10 EIW83255.1 - 6.6e-249 826.6 0.0 9.4e-249 826.1 0.0 1.1 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EIW83255.1 - 3e-16 59.7 8.0 3e-16 59.7 5.6 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIW83255.1 - 6.2e-14 52.3 0.1 7e-13 48.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EIW83255.1 - 9.5e-06 25.3 0.0 0.00016 21.4 0.0 2.3 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EIW83255.1 - 1.2e-05 24.6 0.1 0.00092 18.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 NARP1 PF12569.3 EIW83258.1 - 0.027 13.2 0.4 0.035 12.8 0.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ribosomal_L41 PF05162.8 EIW83259.1 - 0.14 11.8 9.7 0.28 10.8 6.7 1.6 1 0 0 1 1 1 0 Ribosomal protein L41 F-box PF00646.28 EIW83260.1 - 0.00043 19.8 0.8 0.00097 18.7 0.5 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW83260.1 - 0.04 13.6 0.6 0.04 13.6 0.4 1.8 2 0 0 2 2 2 0 F-box-like Lebercilin PF15619.1 EIW83261.1 - 0.0087 15.4 0.8 0.011 15.1 0.6 1.2 1 0 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease YafO_toxin PF13957.1 EIW83261.1 - 0.1 12.3 0.0 0.12 12.2 0.0 1.1 1 0 0 1 1 1 0 Toxin YafO, type II toxin-antitoxin system F-box-like PF12937.2 EIW83262.1 - 2.2e-05 24.0 0.2 7.1e-05 22.4 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EIW83262.1 - 0.0047 16.6 0.5 0.015 15.0 0.0 2.0 2 0 0 2 2 2 1 F-box-like domain F-box PF00646.28 EIW83264.1 - 0.00038 20.0 1.2 0.00085 18.9 0.9 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW83264.1 - 0.037 13.7 0.2 0.11 12.3 0.1 1.8 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.2 EIW83267.1 - 2.1e-06 27.3 1.7 4.5e-06 26.2 1.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW83267.1 - 0.007 15.9 0.7 0.014 15.0 0.5 1.5 1 0 0 1 1 1 1 F-box domain adh_short PF00106.20 EIW83268.1 - 8.8e-25 87.5 0.5 6.5e-24 84.7 0.3 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW83268.1 - 1.2e-17 64.5 0.3 2.7e-17 63.3 0.2 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW83268.1 - 2.8e-11 43.4 0.2 9.3e-11 41.7 0.1 1.8 1 1 1 2 2 2 1 KR domain Pyr_redox PF00070.22 EIW83268.1 - 0.00059 20.1 0.9 0.0059 16.9 0.1 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EIW83268.1 - 0.0036 16.9 0.0 0.0069 16.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EIW83268.1 - 0.0064 16.0 0.2 0.012 15.1 0.0 1.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Polysacc_synt_2 PF02719.10 EIW83268.1 - 0.0083 15.0 0.0 0.017 14.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EIW83268.1 - 0.022 14.7 0.5 0.18 11.8 0.1 2.3 2 1 0 2 2 2 0 NADH(P)-binding Asparaginase_2 PF01112.13 EIW83269.1 - 2.5e-49 167.7 0.7 3.2e-49 167.3 0.5 1.1 1 0 0 1 1 1 1 Asparaginase Tfb4 PF03850.9 EIW83271.1 - 3.3e-82 275.8 0.0 4e-82 275.5 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 DUF1162 PF06650.7 EIW83271.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1162) zf-met2 PF12907.2 EIW83271.1 - 1.4 8.9 0.0 1.4 8.9 0.0 3.3 3 0 0 3 3 3 0 Zinc-binding DUF3619 PF12279.3 EIW83272.1 - 0.1 12.6 4.8 0.058 13.4 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3619) IncA PF04156.9 EIW83272.1 - 1.1 8.8 34.6 2.4 7.7 6.9 3.5 2 1 1 4 4 4 0 IncA protein Spc7 PF08317.6 EIW83272.1 - 1.4 7.4 25.4 2.5 6.6 12.4 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein CENP-Q PF13094.1 EIW83272.1 - 1.5 8.8 24.7 0.59 10.1 0.1 2.5 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Aldolase_II PF00596.16 EIW83272.1 - 2.1 7.8 7.1 0.14 11.7 0.3 2.3 3 0 0 3 3 3 0 Class II Aldolase and Adducin N-terminal domain Fib_alpha PF08702.5 EIW83272.1 - 3.1 7.9 11.9 0.6 10.2 2.9 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family SlyX PF04102.7 EIW83272.1 - 3.5 8.0 15.8 1.9 8.9 1.0 3.7 3 0 0 3 3 3 0 SlyX DivIVA PF05103.8 EIW83272.1 - 7.1 6.7 28.8 2 8.5 4.7 2.3 2 0 0 2 2 2 0 DivIVA protein PPR_2 PF13041.1 EIW83273.1 - 8.6e-31 105.6 0.0 8.6e-08 32.0 0.0 7.1 6 1 1 7 7 7 6 PPR repeat family PPR_3 PF13812.1 EIW83273.1 - 2e-25 86.8 5.9 0.0061 16.7 0.0 10.2 10 0 0 10 10 10 4 Pentatricopeptide repeat domain PPR_1 PF12854.2 EIW83273.1 - 1.7e-13 49.7 0.1 0.031 13.7 0.0 7.0 7 0 0 7 7 7 3 PPR repeat PPR PF01535.15 EIW83273.1 - 3.9e-12 45.2 7.0 0.069 13.1 0.0 9.0 10 1 0 10 10 10 2 PPR repeat TPR_7 PF13176.1 EIW83273.1 - 0.0055 16.4 0.2 0.028 14.1 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat GMP_synt_C PF00958.17 EIW83273.1 - 0.031 13.9 0.0 9.3 6.0 0.0 2.4 2 0 0 2 2 2 0 GMP synthase C terminal domain ECSIT PF06239.6 EIW83273.1 - 0.064 12.1 0.0 4.3 6.1 0.1 3.5 3 1 0 3 3 3 0 Evolutionarily conserved signalling intermediate in Toll pathway TPR_14 PF13428.1 EIW83273.1 - 0.16 12.6 7.1 0.21 12.3 0.4 4.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EIW83273.1 - 7 7.4 8.0 1.5 9.6 0.3 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Rad21_Rec8_N PF04825.8 EIW83274.1 - 6.3e-41 138.8 0.1 1e-40 138.1 0.1 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EIW83274.1 - 5.8e-11 41.4 0.0 1.1e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein HbrB PF08539.6 EIW83277.1 - 1.1e-33 116.3 0.1 1.5e-33 115.8 0.1 1.2 1 0 0 1 1 1 1 HbrB-like NAD_binding_4 PF07993.7 EIW83278.1 - 6.8e-42 143.1 0.0 1e-41 142.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EIW83278.1 - 1.5e-34 119.0 0.0 2.7e-34 118.2 0.0 1.4 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EIW83278.1 - 1.2e-12 47.8 0.0 2.6e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EIW83278.1 - 2e-11 43.9 0.1 6e-11 42.4 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EIW83278.1 - 5.8e-06 26.3 0.3 1.5e-05 24.9 0.2 1.7 1 1 0 1 1 1 1 short chain dehydrogenase TM140 PF14985.1 EIW83278.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 TM140 protein family KR PF08659.5 EIW83278.1 - 0.019 14.6 0.2 0.055 13.1 0.2 1.7 1 1 0 1 1 1 0 KR domain Amidase PF01425.16 EIW83278.1 - 0.048 12.5 0.0 0.085 11.6 0.0 1.3 1 0 0 1 1 1 0 Amidase WD40 PF00400.27 EIW83279.1 - 1.8e-32 110.0 15.4 1.3e-07 31.2 0.0 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW83279.1 - 5.2e-06 26.0 0.8 0.016 14.6 0.0 2.4 1 1 0 2 2 2 2 PQQ-like domain Me-amine-dh_H PF06433.6 EIW83279.1 - 0.051 12.2 0.0 0.083 11.5 0.0 1.4 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) BBS2_Mid PF14783.1 EIW83279.1 - 0.075 12.8 0.0 15 5.3 0.0 3.7 5 1 0 5 5 5 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 EIW83279.1 - 0.14 12.4 2.4 1.3 9.4 0.0 3.5 4 1 0 4 4 4 0 PQQ-like domain ICMT PF04140.9 EIW83280.1 - 3.1e-12 46.5 0.3 1.1e-11 44.7 0.0 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIW83280.1 - 7.7e-09 35.6 1.2 4.4e-08 33.1 0.2 2.2 1 1 1 2 2 2 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EIW83280.1 - 0.00046 18.8 0.1 0.00067 18.3 0.1 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Abhydrolase_6 PF12697.2 EIW83281.1 - 2.1e-27 96.4 0.2 2.4e-27 96.2 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW83281.1 - 4.2e-16 58.9 0.0 5.9e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EIW83281.1 - 2e-05 24.3 0.0 3.5e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF900 PF05990.7 EIW83281.1 - 7.6e-05 22.1 0.0 0.00011 21.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_8 PF06259.7 EIW83281.1 - 0.005 16.3 0.0 0.0077 15.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase Ser_hydrolase PF06821.8 EIW83281.1 - 0.018 14.6 0.0 0.031 13.8 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_1 PF00561.15 EIW83281.1 - 0.02 14.4 0.0 0.039 13.4 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EIW83281.1 - 0.02 14.7 0.0 0.096 12.5 0.0 2.0 2 0 0 2 2 2 0 Putative lysophospholipase DLH PF01738.13 EIW83281.1 - 0.02 14.1 0.0 0.041 13.1 0.0 1.5 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF676 PF05057.9 EIW83281.1 - 0.036 13.3 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Thioesterase PF00975.15 EIW83281.1 - 0.12 12.6 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain zf-C2H2 PF00096.21 EIW83282.1 - 9.3e-13 47.7 11.5 0.00013 22.1 0.3 3.1 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW83282.1 - 1.1e-10 40.9 11.8 0.00076 19.6 0.3 3.1 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIW83282.1 - 8e-08 32.2 13.0 2.1e-06 27.7 0.1 3.7 3 1 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EIW83282.1 - 1.9e-05 24.3 4.7 0.039 13.8 0.0 3.0 3 1 1 4 4 4 2 C2H2-type zinc finger zf-met PF12874.2 EIW83282.1 - 0.0012 18.9 4.9 0.99 9.7 0.1 3.3 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-TRAF PF02176.13 EIW83282.1 - 0.0025 18.1 2.6 0.0077 16.5 0.2 2.2 1 1 0 2 2 2 1 TRAF-type zinc finger zf-RING_3 PF14369.1 EIW83282.1 - 0.009 15.9 6.8 0.054 13.5 0.8 3.1 3 0 0 3 3 3 1 zinc-finger zf-Di19 PF05605.7 EIW83282.1 - 0.018 15.1 3.5 0.13 12.4 1.5 2.1 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding IBR PF01485.16 EIW83282.1 - 0.025 14.4 5.6 0.11 12.3 2.0 2.1 1 1 1 2 2 2 0 IBR domain zf-LYAR PF08790.6 EIW83282.1 - 0.088 12.5 5.4 4.3 7.1 0.0 3.2 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-RING_4 PF14570.1 EIW83282.1 - 0.23 11.0 3.7 0.61 9.7 2.6 1.9 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc-ribbons_6 PF07191.7 EIW83282.1 - 0.33 10.7 2.5 1.4 8.7 1.4 2.1 2 1 1 3 3 3 0 zinc-ribbons zf-C2H2_jaz PF12171.3 EIW83282.1 - 0.44 10.7 5.9 20 5.4 0.0 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2HC_2 PF13913.1 EIW83282.1 - 1.2 8.8 0.1 1.2 8.8 0.1 2.9 3 1 0 3 3 2 0 zinc-finger of a C2HC-type Zn-ribbon_8 PF09723.5 EIW83282.1 - 1.7 8.6 7.4 55 3.8 0.0 3.1 2 1 1 3 3 3 0 Zinc ribbon domain zf-CCHC_5 PF14787.1 EIW83282.1 - 3.3 7.2 7.7 5.5 6.5 0.1 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger PK PF00224.16 EIW83283.1 - 0.057 12.0 0.0 0.089 11.3 0.0 1.2 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain OATP PF03137.15 EIW83283.1 - 0.26 9.2 1.9 0.45 8.5 1.3 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF3421 PF11901.3 EIW83284.1 - 5.4e-26 90.6 4.0 3.3e-19 68.7 0.3 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) U3_assoc_6 PF08640.6 EIW83286.1 - 1.1e-26 92.3 4.8 2e-25 88.3 3.6 2.5 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 EIW83286.1 - 0.013 14.4 0.2 3.7 6.3 0.0 2.7 2 1 1 3 3 3 0 NRDE-2, necessary for RNA interference Ribosomal_S21 PF01165.15 EIW83286.1 - 0.14 11.6 2.4 11 5.5 0.2 3.6 2 0 0 2 2 2 0 Ribosomal protein S21 Ribosomal_L12 PF00542.14 EIW83286.1 - 0.46 10.5 5.8 1.6 8.7 0.2 3.7 4 0 0 4 4 4 0 Ribosomal protein L7/L12 C-terminal domain FAD_binding_3 PF01494.14 EIW83288.1 - 4.5e-31 108.2 0.0 6e-31 107.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIW83288.1 - 8.6e-07 28.1 0.1 0.029 13.2 0.0 2.6 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW83288.1 - 4.5e-06 26.9 0.1 0.24 11.8 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW83288.1 - 0.0006 19.7 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIW83288.1 - 0.00086 19.2 0.1 0.0027 17.6 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW83288.1 - 0.0047 15.8 0.1 0.038 12.8 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 EIW83288.1 - 0.042 13.5 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.5 EIW83288.1 - 0.073 11.8 0.0 6.7 5.4 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase Abhydrolase_6 PF12697.2 EIW83290.1 - 2.9e-07 30.5 0.0 4.5e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ribosomal_L11_N PF03946.9 EIW83291.1 - 1e-17 63.3 0.1 1.7e-17 62.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EIW83291.1 - 5.1e-12 45.7 0.3 8.9e-12 44.9 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Cyclin PF08613.6 EIW83292.1 - 7.1e-28 97.8 0.1 1.1e-27 97.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EIW83292.1 - 6.6e-05 22.4 0.0 0.0001 21.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ras PF00071.17 EIW83293.1 - 9.7e-39 132.3 0.0 1.2e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW83293.1 - 8.5e-14 52.0 0.0 1.2e-13 51.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW83293.1 - 7.9e-11 41.5 0.0 1.1e-10 40.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIW83293.1 - 0.00048 19.6 0.1 0.0042 16.5 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 EIW83293.1 - 0.0034 16.9 0.0 0.0065 16.0 0.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIW83293.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Pkinase PF00069.20 EIW83295.1 - 3.3e-39 134.6 0.0 2.3e-25 89.2 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW83295.1 - 2.3e-18 66.2 0.0 3.8e-18 65.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW83295.1 - 0.0026 16.7 0.0 0.0049 15.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Imm5 PF14423.1 EIW83296.1 - 0.33 10.5 2.3 0.97 9.0 0.9 1.9 2 0 0 2 2 2 0 Immunity protein Imm5 Methyltransf_25 PF13649.1 EIW83297.1 - 1.2e-07 31.9 0.0 3.9e-07 30.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW83297.1 - 0.00095 18.9 0.0 0.0015 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW83297.1 - 0.056 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EIW83297.1 - 0.072 13.6 0.0 0.12 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EIW83297.1 - 0.15 11.0 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Trypan_PARP PF05887.6 EIW83299.1 - 0.0056 16.4 18.3 0.0056 16.4 12.7 5.3 5 1 0 5 5 5 2 Procyclic acidic repetitive protein (PARP) Cauli_VI PF01693.11 EIW83301.1 - 0.00026 20.9 0.0 0.00041 20.3 0.0 1.2 1 0 0 1 1 1 1 Caulimovirus viroplasmin DUF2742 PF10888.3 EIW83303.1 - 0.19 11.6 2.4 0.27 11.1 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2742) Nucleos_tra2_C PF07662.8 EIW83305.1 - 1e-66 224.4 3.5 1e-66 224.4 2.4 2.4 3 0 0 3 3 3 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EIW83305.1 - 6.7e-15 55.1 3.0 6.7e-15 55.1 2.1 4.1 3 1 0 3 3 3 1 Na+ dependent nucleoside transporter N-terminus GlnE PF03710.10 EIW83306.1 - 0.065 12.4 0.0 0.096 11.9 0.0 1.2 1 0 0 1 1 1 0 Glutamate-ammonia ligase adenylyltransferase PMI_typeI PF01238.16 EIW83307.1 - 6.5e-108 361.0 0.0 7.6e-108 360.8 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 EIW83307.1 - 2.6e-06 26.8 0.1 0.0034 16.8 0.0 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EIW83307.1 - 0.0093 15.6 0.1 2.4 7.8 0.0 2.7 3 0 0 3 3 3 2 AraC-like ligand binding domain EutQ PF06249.7 EIW83307.1 - 0.17 11.3 0.0 0.32 10.5 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ DUF3421 PF11901.3 EIW83308.1 - 3.7e-24 84.7 1.8 4.6e-18 65.0 0.1 3.3 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) CBM_5_12 PF02839.9 EIW83308.1 - 1.7e-05 24.3 5.5 4.6e-05 22.9 3.0 2.5 2 0 0 2 2 2 1 Carbohydrate binding domain WD40 PF00400.27 EIW83309.1 - 5.4e-20 70.4 2.5 3.6e-07 29.8 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Serglycin PF04360.7 EIW83309.1 - 0.029 14.0 4.7 0.11 12.2 0.1 3.0 3 0 0 3 3 3 0 Serglycin Apc4_WD40 PF12894.2 EIW83309.1 - 0.095 12.2 0.6 3.5 7.1 0.0 3.4 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain RPA_interact_C PF14768.1 EIW83310.1 - 0.025 14.9 0.1 0.039 14.3 0.0 1.3 1 0 0 1 1 1 0 Replication protein A interacting C-terminal MPC PF03650.8 EIW83311.1 - 2e-38 130.9 0.4 2.4e-38 130.7 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) Palm_thioest PF02089.10 EIW83312.1 - 9.9e-58 195.2 0.0 1.2e-50 172.0 0.0 2.0 2 0 0 2 2 2 2 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.15 EIW83312.1 - 0.0032 17.0 0.0 0.0041 16.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.6 EIW83312.1 - 0.0053 15.8 0.0 0.013 14.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.2 EIW83312.1 - 0.062 13.0 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EIW83312.1 - 0.078 12.4 0.7 0.27 10.6 0.0 2.0 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase DCAF15_WD40 PF14939.1 EIW83312.1 - 0.16 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat Bundlin PF05307.6 EIW83313.1 - 0.028 14.2 0.0 0.059 13.2 0.0 1.5 1 0 0 1 1 1 0 Bundlin p450 PF00067.17 EIW83314.1 - 5.1e-67 226.3 0.0 1.2e-66 225.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Ribosomal_S5 PF00333.15 EIW83315.1 - 5.7e-28 96.4 1.3 5.7e-28 96.4 0.9 1.7 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EIW83315.1 - 3.3e-21 74.3 0.1 5.7e-21 73.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain RNA_pol PF00940.14 EIW83315.1 - 0.18 10.2 0.0 0.26 9.7 0.0 1.1 1 0 0 1 1 1 0 DNA-dependent RNA polymerase FoP_duplication PF13865.1 EIW83315.1 - 6.1 7.3 7.4 12 6.3 5.1 1.5 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 ODC_AZ PF02100.12 EIW83317.1 - 1.2e-19 69.8 0.0 1.3e-19 69.6 0.0 1.1 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme S4 PF01479.20 EIW83317.1 - 0.088 12.2 0.0 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 S4 domain DUF1771 PF08590.5 EIW83318.1 - 2e-21 75.7 6.4 2e-21 75.7 4.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EIW83318.1 - 1.3e-14 54.1 0.1 2.6e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 Smr domain Seryl_tRNA_N PF02403.17 EIW83318.1 - 0.9 9.5 3.6 0.65 10.0 1.2 1.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ATP-synt_B PF00430.13 EIW83318.1 - 3.1 7.6 5.0 1 9.1 1.6 1.6 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DnaJ PF00226.26 EIW83319.1 - 2.4e-11 43.1 0.2 4.2e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain F-box-like PF12937.2 EIW83321.1 - 6.2e-05 22.6 2.0 0.098 12.4 0.1 2.5 2 0 0 2 2 2 2 F-box-like Vps8 PF12816.2 EIW83322.1 - 2e-63 213.2 0.0 6.6e-61 204.9 0.0 2.5 2 0 0 2 2 2 2 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EIW83322.1 - 0.016 14.7 0.0 0.39 10.3 0.0 2.4 2 0 0 2 2 2 0 Region in Clathrin and VPS PQQ_3 PF13570.1 EIW83322.1 - 0.02 15.1 1.0 0.42 10.9 0.1 2.9 2 0 0 2 2 2 0 PQQ-like domain Nbas_N PF15492.1 EIW83322.1 - 0.054 12.6 0.0 0.094 11.7 0.0 1.3 1 0 0 1 1 1 0 Neuroblastoma-amplified sequence, N terminal PPP4R2 PF09184.6 EIW83323.1 - 1.7 8.1 29.8 1.5 8.2 8.8 3.1 2 1 1 3 3 3 0 PPP4R2 DNA_pol_phi PF04931.8 EIW83323.1 - 9.4 3.8 12.1 17 3.0 8.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi Pkinase PF00069.20 EIW83326.1 - 0.0052 15.9 0.0 0.0078 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF3510 PF12022.3 EIW83328.1 - 1.3e-17 64.0 0.0 1.8e-17 63.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3510) COG2 PF06148.6 EIW83330.1 - 2.7e-28 98.4 2.2 2.7e-28 98.4 1.5 2.4 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.3 EIW83330.1 - 2.8e-24 85.6 0.0 1.7e-23 83.0 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) Vps51 PF08700.6 EIW83330.1 - 0.0048 16.6 0.7 0.032 14.0 0.1 2.6 2 0 0 2 2 2 1 Vps51/Vps67 Spc7 PF08317.6 EIW83330.1 - 0.039 12.6 1.4 0.088 11.4 1.0 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein YrbL-PhoP_reg PF10707.4 EIW83331.1 - 0.0036 16.6 0.0 1.9 7.7 0.0 2.2 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL Pkinase PF00069.20 EIW83331.1 - 0.019 14.1 0.0 0.027 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein kinase domain Methyltransf_25 PF13649.1 EIW83332.1 - 1.5e-07 31.7 0.0 1.8e-06 28.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW83332.1 - 0.019 14.7 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EIW83332.1 - 0.09 13.2 0.0 0.57 10.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Fungal_trans PF04082.13 EIW83333.1 - 4.3e-18 65.1 0.1 8.1e-18 64.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW83333.1 - 2e-08 33.9 11.5 3.2e-08 33.3 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 EIW83333.1 - 0.032 14.1 0.0 0.076 12.9 0.0 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain DUF1203 PF06718.6 EIW83333.1 - 0.12 12.1 0.5 4.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1203) DUF1674 PF07896.7 EIW83334.1 - 8.7e-12 45.0 4.5 1.3e-11 44.4 3.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) LSM PF01423.17 EIW83335.1 - 2.7e-12 46.0 0.2 3.5e-12 45.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EIW83335.1 - 0.0076 16.1 0.0 0.012 15.4 0.0 1.3 1 1 0 1 1 1 1 Ataxin 2 SM domain Voltage_CLC PF00654.15 EIW83336.1 - 2e-94 316.5 24.7 4.1e-94 315.5 14.5 2.2 2 0 0 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 EIW83336.1 - 0.039 13.7 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 CBS domain YrbL-PhoP_reg PF10707.4 EIW83337.1 - 0.0042 16.4 0.0 2.3 7.4 0.0 2.2 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL YrbL-PhoP_reg PF10707.4 EIW83338.1 - 0.004 16.5 0.0 0.11 11.8 0.0 2.2 2 0 0 2 2 2 2 PhoP regulatory network protein YrbL F-box-like PF12937.2 EIW83339.1 - 7e-06 25.6 0.2 0.00013 21.5 0.0 3.0 3 1 0 3 3 3 1 F-box-like DUF2797 PF10977.3 EIW83339.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) APH PF01636.18 EIW83340.1 - 0.023 14.4 3.6 0.056 13.1 2.5 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EIW83340.1 - 0.031 13.6 0.0 1.7 7.9 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL YrbL-PhoP_reg PF10707.4 EIW83341.1 - 0.071 12.4 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL PALP PF00291.20 EIW83342.1 - 1.8e-75 253.9 0.1 2.7e-75 253.4 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EIW83342.1 - 2.5e-37 126.3 0.0 7.5e-24 83.1 0.0 2.4 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase PHD PF00628.24 EIW83343.1 - 4e-11 42.4 8.1 6.6e-11 41.7 5.6 1.4 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EIW83343.1 - 0.019 14.2 3.8 0.035 13.4 2.6 1.3 1 0 0 1 1 1 0 PHD-finger NDUF_B12 PF08122.7 EIW83344.1 - 1.5e-20 72.6 0.3 1.7e-20 72.4 0.2 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Cation_ATPase_C PF00689.16 EIW83344.1 - 0.026 14.0 0.0 0.029 13.8 0.0 1.0 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus Topoisom_I_N PF02919.10 EIW83345.1 - 3.7e-94 314.0 1.0 3.7e-94 314.0 0.7 2.8 2 1 0 2 2 2 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EIW83345.1 - 2.9e-89 298.2 5.1 9.1e-89 296.5 3.6 1.8 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EIW83345.1 - 1.9e-33 113.9 0.2 6.1e-33 112.3 0.1 1.9 1 0 0 1 1 1 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 EIW83345.1 - 0.68 9.0 3.4 0.8 8.8 0.0 2.5 3 0 0 3 3 3 0 RolB/RolC glucosidase family Pkinase PF00069.20 EIW83346.1 - 6e-07 28.8 0.0 1.1e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW83346.1 - 0.00011 21.3 0.0 0.00019 20.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase CTP_transf_1 PF01148.15 EIW83347.1 - 6.5e-74 248.8 25.6 8.1e-74 248.5 17.7 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF2839 PF10999.3 EIW83347.1 - 0.026 14.5 0.8 0.072 13.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) Ribosom_S12_S23 PF00164.20 EIW83348.1 - 1.1e-36 124.9 0.2 1.2e-36 124.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Topoisom_I PF01028.15 EIW83349.1 - 3e-88 294.8 4.2 9.4e-88 293.2 2.9 1.8 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.10 EIW83349.1 - 4.6e-75 251.6 18.4 1.1e-46 158.8 0.3 3.9 2 2 1 3 3 3 2 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.1 EIW83349.1 - 2.5e-33 113.5 0.2 6.4e-33 112.2 0.1 1.8 1 0 0 1 1 1 1 C-terminal topoisomerase domain Pkinase PF00069.20 EIW83350.1 - 6.1e-07 28.8 0.0 1.3e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW83350.1 - 0.00015 20.9 0.0 0.00028 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase NARP1 PF12569.3 EIW83351.1 - 1 8.0 5.2 2.4 6.8 0.2 2.0 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 IER PF05760.7 EIW83351.1 - 2.6 7.8 10.1 3.5 7.4 7.0 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) CTP_transf_1 PF01148.15 EIW83352.1 - 1.7e-64 217.9 19.0 2.1e-64 217.6 13.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Ribosom_S12_S23 PF00164.20 EIW83353.1 - 1.2e-39 134.5 0.8 1.4e-39 134.3 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Abhydrolase_1 PF00561.15 EIW83354.1 - 4.8e-12 45.9 0.3 9.6e-12 44.9 0.2 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIW83354.1 - 2.7e-11 43.7 0.1 4.2e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 EIW83355.1 - 2.9e-51 174.4 0.0 3.6e-51 174.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3096 PF11295.3 EIW83355.1 - 0.14 11.6 0.1 0.31 10.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3096) DUF3419 PF11899.3 EIW83356.1 - 4.2e-125 417.4 0.0 5.6e-125 416.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_11 PF08241.7 EIW83356.1 - 7.3e-08 32.7 0.0 3.8e-05 24.0 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW83356.1 - 2.4e-07 30.1 0.0 8.8e-07 28.2 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EIW83356.1 - 2.9e-07 30.8 0.0 5.5e-06 26.7 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW83356.1 - 2.3e-06 27.4 0.0 6.5e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW83356.1 - 2e-05 25.1 0.0 6.6e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW83356.1 - 2.4e-05 23.9 0.0 5.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW83356.1 - 4e-05 23.9 0.0 0.00026 21.3 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW83356.1 - 0.0022 18.0 2.5 0.031 14.2 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIW83356.1 - 0.013 14.5 0.0 0.033 13.2 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase Peptidase_S64 PF08192.6 EIW83357.1 - 2.2e-05 23.0 0.0 7.1e-05 21.3 0.0 1.6 2 0 0 2 2 2 1 Peptidase family S64 CMAS PF02353.15 EIW83358.1 - 4.6e-33 114.4 0.1 6.3e-33 114.0 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 EIW83358.1 - 8.2e-13 48.2 0.0 1.4e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW83358.1 - 6.1e-12 45.8 0.0 1.1e-11 45.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW83358.1 - 8.5e-12 45.6 0.0 1.4e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW83358.1 - 9.8e-09 35.5 0.0 2e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW83358.1 - 3.6e-08 32.9 0.0 5.4e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EIW83358.1 - 4.2e-08 33.0 0.0 7.5e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW83358.1 - 8.7e-07 29.2 0.0 1.8e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain tRNA_U5-meth_tr PF05958.6 EIW83358.1 - 2.2e-05 23.3 0.0 3.1e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TehB PF03848.9 EIW83358.1 - 2.5e-05 23.5 0.0 4.3e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_4 PF02390.12 EIW83358.1 - 5e-05 22.4 0.0 0.00011 21.3 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase GidB PF02527.10 EIW83358.1 - 0.0027 16.8 0.0 0.0045 16.1 0.0 1.3 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G PCMT PF01135.14 EIW83358.1 - 0.0096 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EIW83358.1 - 0.018 15.0 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 EIW83358.1 - 0.02 14.4 0.0 0.099 12.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF938) Sirohm_synth_C PF14823.1 EIW83358.1 - 0.085 12.1 0.1 0.16 11.3 0.1 1.4 1 0 0 1 1 1 0 Sirohaem biosynthesis protein C-terminal MetW PF07021.7 EIW83358.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RrnaAD PF00398.15 EIW83358.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MDM31_MDM32 PF08118.6 EIW83359.1 - 5.9e-136 453.8 5.2 1.1e-61 208.8 0.0 3.0 3 0 0 3 3 3 3 Yeast mitochondrial distribution and morphology (MDM) proteins Sugar_tr PF00083.19 EIW83360.1 - 2.5e-115 385.6 17.4 5.6e-115 384.4 12.1 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW83360.1 - 7.6e-20 70.9 46.4 2e-12 46.5 15.7 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIW83360.1 - 0.0023 16.1 2.4 0.0023 16.1 1.7 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIW83361.1 - 7.5e-103 344.5 23.9 3e-101 339.2 16.6 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW83361.1 - 5e-20 71.5 32.0 8.8e-19 67.4 20.2 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily APH PF01636.18 EIW83362.1 - 0.033 13.8 0.5 0.055 13.1 0.3 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family APH PF01636.18 EIW83364.1 - 0.029 14.1 0.2 0.036 13.7 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EIW83364.1 - 0.15 11.4 0.0 12 5.1 0.0 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Nucleoporin_FG PF13634.1 EIW83365.1 - 0.029 14.6 3.4 0.049 13.8 2.4 1.3 1 0 0 1 1 1 0 Nucleoporin FG repeat region COG5 PF10392.4 EIW83365.1 - 0.062 13.2 0.9 0.086 12.8 0.6 1.3 1 1 0 1 1 1 0 Golgi transport complex subunit 5 ATP-synt_B PF00430.13 EIW83365.1 - 1.2 8.9 9.7 1.7 8.4 6.8 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) NOG1 PF06858.9 EIW83366.1 - 1.5e-27 95.2 0.0 2.9e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.6 EIW83366.1 - 1.5e-26 91.8 0.9 3.5e-26 90.6 0.6 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.18 EIW83366.1 - 2.3e-16 59.7 0.0 5.4e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIW83366.1 - 4.9e-10 38.8 0.0 1.1e-09 37.8 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EIW83366.1 - 0.0018 18.7 0.0 0.0049 17.3 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 EIW83366.1 - 0.004 16.3 0.0 0.041 13.0 0.0 2.3 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EIW83366.1 - 0.0075 15.4 0.0 0.015 14.4 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EIW83366.1 - 0.46 10.2 2.8 2.7 7.7 0.0 2.8 3 1 1 4 4 4 0 Dynamin family Peptidase_M24 PF00557.19 EIW83367.1 - 6.5e-41 140.1 0.0 9.2e-41 139.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EIW83367.1 - 2.4e-21 76.5 0.0 4.8e-20 72.3 0.0 2.4 2 0 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Sugar_tr PF00083.19 EIW83368.1 - 2.8e-78 263.5 26.6 4.7e-71 239.6 7.6 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EIW83368.1 - 6.5e-28 97.4 19.8 1.7e-27 96.0 13.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIW83368.1 - 5.1e-05 21.8 1.0 5.1e-05 21.8 0.7 3.4 2 2 1 3 3 3 2 MFS/sugar transport protein MFS_3 PF05977.8 EIW83368.1 - 0.0027 15.8 0.3 0.22 9.5 0.0 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector DUF1275 PF06912.6 EIW83368.1 - 0.0088 15.2 5.8 0.11 11.6 0.3 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1275) Equine_IAV_S2 PF06502.6 EIW83368.1 - 0.14 12.0 0.0 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Equine infectious anaemia virus S2 protein Sugar_tr PF00083.19 EIW83369.1 - 1.6e-69 234.6 26.3 3e-65 220.5 12.7 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EIW83369.1 - 7.2e-22 77.5 26.8 7.2e-22 77.5 18.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EIW83369.1 - 0.00024 19.6 26.8 0.00071 18.0 5.5 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein tRNA-synt_2 PF00152.15 EIW83371.1 - 7e-89 297.8 0.0 1e-88 297.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EIW83371.1 - 2.3e-10 40.1 0.0 7.3e-10 38.5 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EIW83371.1 - 3.1e-08 33.1 0.0 0.0002 20.6 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EIW83371.1 - 0.051 13.1 0.0 11 5.5 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) IBR PF01485.16 EIW83372.1 - 4.9e-15 55.1 41.4 8.7e-10 38.3 11.2 3.8 3 1 0 3 3 3 2 IBR domain zf-C3HC4_2 PF13923.1 EIW83372.1 - 9.4e-06 25.5 5.9 9.4e-06 25.5 4.1 4.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW83372.1 - 2.2e-05 24.0 32.4 8.4e-05 22.1 2.9 4.2 3 1 1 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW83372.1 - 0.00011 21.9 6.2 0.00011 21.9 4.3 3.5 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4_3 PF13920.1 EIW83372.1 - 0.00094 18.8 5.3 0.00094 18.8 3.7 4.3 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW83372.1 - 0.002 17.8 6.2 0.002 17.8 4.3 3.6 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EIW83372.1 - 0.004 17.0 2.8 0.004 17.0 1.9 4.4 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING Glyco_tranf_2_3 PF13641.1 EIW83373.1 - 5.7e-25 88.4 0.0 8.3e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EIW83373.1 - 1.8e-10 40.7 0.0 2.7e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EIW83373.1 - 1.6e-09 37.3 0.0 4e-09 36.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.1 EIW83373.1 - 1.7e-06 27.8 6.5 3e-06 27.0 4.5 1.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Chitin_synth_2 PF03142.10 EIW83373.1 - 0.12 10.7 1.7 0.38 9.0 1.2 1.7 1 1 0 1 1 1 0 Chitin synthase Serglycin PF04360.7 EIW83373.1 - 0.4 10.3 2.2 0.77 9.4 1.5 1.4 1 0 0 1 1 1 0 Serglycin HEPN PF05168.9 EIW83376.1 - 0.094 12.6 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 HEPN domain Condensin2nSMC PF12422.3 EIW83377.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Condensin II non structural maintenance of chromosomes subunit Rubis-subs-bind PF09273.6 EIW83379.1 - 1e-11 44.8 0.0 1.8e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 EIW83379.1 - 8.6e-09 35.8 0.0 2.8e-08 34.2 0.0 1.8 1 1 0 1 1 1 1 SET domain STE3 PF02076.10 EIW83380.1 - 4.5e-36 124.3 7.0 5.3e-36 124.1 4.9 1.1 1 0 0 1 1 1 1 Pheromone A receptor FAD_binding_3 PF01494.14 EIW83381.1 - 6.9e-20 71.3 0.2 3.5e-19 69.0 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EIW83381.1 - 4.3e-09 35.7 0.8 1.6e-08 33.9 0.6 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EIW83381.1 - 1.3e-08 34.7 0.9 3.8e-08 33.2 0.6 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EIW83381.1 - 3.5e-08 32.5 1.1 1.3e-05 24.0 0.8 2.3 1 1 1 2 2 2 2 Tryptophan halogenase DAO PF01266.19 EIW83381.1 - 1.3e-07 30.8 6.8 1.6e-06 27.2 2.8 2.4 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW83381.1 - 5.5e-07 28.7 5.4 6.1e-07 28.6 2.9 1.7 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EIW83381.1 - 2.1e-06 27.0 0.1 2.1e-06 27.0 0.1 1.5 2 0 0 2 2 2 1 Thi4 family Amino_oxidase PF01593.19 EIW83381.1 - 1.3e-05 24.4 3.2 3.3e-05 23.1 0.7 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EIW83381.1 - 1.5e-05 23.6 2.7 0.00076 18.0 1.4 2.5 3 0 0 3 3 3 1 HI0933-like protein FAD_oxidored PF12831.2 EIW83381.1 - 1.6e-05 24.1 0.3 2.2e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW83381.1 - 3e-05 24.3 0.2 0.00015 22.0 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW83381.1 - 7.1e-05 22.7 2.3 0.00014 21.8 1.6 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW83381.1 - 8.8e-05 22.6 0.0 0.00015 21.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIW83381.1 - 0.00029 19.8 2.6 0.00056 18.8 1.8 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A 3HCDH_N PF02737.13 EIW83381.1 - 0.014 15.0 0.7 0.031 13.9 0.5 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EIW83381.1 - 0.025 14.1 0.6 0.06 12.9 0.4 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.1 EIW83381.1 - 0.084 12.6 0.4 0.35 10.6 0.2 2.1 1 1 0 1 1 1 0 FAD-NAD(P)-binding ApbA PF02558.11 EIW83381.1 - 0.72 9.2 2.7 1.3 8.4 1.8 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Metallophos PF00149.23 EIW83382.1 - 2.9e-40 137.8 0.3 3.7e-40 137.4 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIW83382.1 - 0.0048 16.7 0.0 0.0063 16.3 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain zf-C2H2_4 PF13894.1 EIW83383.1 - 1.4e-07 31.3 11.6 0.00011 22.2 2.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIW83383.1 - 0.00041 20.5 15.3 0.065 13.6 2.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW83383.1 - 0.002 18.3 4.5 1.1 9.7 0.0 2.9 2 0 0 2 2 2 2 Zinc-finger double domain zf-met PF12874.2 EIW83383.1 - 0.0055 16.8 0.6 0.1 12.8 0.1 2.8 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIW83383.1 - 7.3 6.8 9.7 1.8 8.7 0.2 2.9 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-CCCH PF00642.19 EIW83384.1 - 4.4e-09 35.8 2.5 9.5e-09 34.7 1.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.1 EIW83384.1 - 1.7e-07 30.8 4.9 2.7e-07 30.1 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW83384.1 - 6.8e-07 28.9 7.5 1.1e-06 28.2 5.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIW83384.1 - 3.5e-06 26.9 9.6 6e-06 26.1 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW83384.1 - 9.4e-05 21.9 8.7 0.00017 21.1 6.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW83384.1 - 0.00016 21.4 6.8 0.00028 20.6 4.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EIW83384.1 - 0.00033 20.3 2.1 0.001 18.7 1.4 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EIW83384.1 - 0.008 16.0 7.4 0.018 14.8 5.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RanBP PF00641.13 EIW83384.1 - 0.045 12.8 0.7 0.1 11.6 0.5 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others zf-Nse PF11789.3 EIW83384.1 - 0.049 13.1 0.8 0.084 12.4 0.5 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Arf PF00025.16 EIW83385.1 - 1.5e-37 128.5 0.0 7.7e-37 126.2 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EIW83385.1 - 1.2e-11 43.9 0.0 3.6e-07 29.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EIW83385.1 - 1.2e-07 31.3 0.0 1.7e-07 30.7 0.0 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EIW83385.1 - 2e-07 31.5 0.0 3.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EIW83385.1 - 3.9e-06 26.1 0.0 4.7e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EIW83385.1 - 5.9e-06 25.6 0.0 8.5e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EIW83385.1 - 8.3e-05 22.5 0.0 0.00013 21.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.14 EIW83385.1 - 0.0012 18.3 0.0 0.11 11.9 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.22 EIW83385.1 - 0.0014 18.0 0.0 0.033 13.6 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EIW83385.1 - 0.0026 17.8 0.0 0.0037 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIW83385.1 - 0.0076 16.5 0.1 0.014 15.7 0.1 1.4 1 0 0 1 1 1 1 ABC transporter AAA_15 PF13175.1 EIW83385.1 - 0.021 13.9 0.1 0.026 13.5 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 EIW83385.1 - 0.024 14.9 0.7 0.023 15.0 0.5 1.3 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EIW83385.1 - 0.026 14.0 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 EIW83385.1 - 0.03 13.6 0.0 0.046 13.0 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase AAA_16 PF13191.1 EIW83385.1 - 0.036 14.0 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain SRP54 PF00448.17 EIW83385.1 - 0.038 13.4 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_21 PF13304.1 EIW83385.1 - 0.058 13.3 0.2 0.059 13.3 0.2 1.3 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIW83385.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 EIW83385.1 - 0.068 12.8 0.0 0.19 11.4 0.0 1.6 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 EIW83385.1 - 0.072 12.9 0.0 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.3 EIW83385.1 - 0.073 10.4 0.1 0.091 10.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Zeta_toxin PF06414.7 EIW83385.1 - 0.1 11.6 0.0 0.23 10.5 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin Arch_ATPase PF01637.13 EIW83385.1 - 0.15 11.7 0.1 0.26 10.9 0.1 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_18 PF13238.1 EIW83385.1 - 0.18 12.1 1.2 0.34 11.2 0.8 1.8 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EIW83385.1 - 0.22 12.3 3.7 0.7 10.7 2.6 2.1 1 1 0 1 1 1 0 AAA domain ATP-synt_C PF00137.16 EIW83386.1 - 1.4e-27 95.3 28.1 1.5e-16 60.0 6.1 2.8 3 0 0 3 3 3 2 ATP synthase subunit C G0-G1_switch_2 PF15103.1 EIW83386.1 - 0.0053 16.9 0.6 0.23 11.6 0.1 2.3 2 0 0 2 2 2 1 G0/G1 switch protein 2 Sensor_TM1 PF13755.1 EIW83386.1 - 0.062 12.8 0.9 2.1 7.9 0.1 2.4 2 0 0 2 2 2 0 Sensor N-terminal transmembrane domain Oxidored_q2 PF00420.19 EIW83386.1 - 0.24 11.0 5.6 0.2 11.2 1.9 2.4 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L E1-E2_ATPase PF00122.15 EIW83387.1 - 6.9e-62 208.4 0.5 6.9e-62 208.4 0.3 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EIW83387.1 - 2.4e-23 83.6 0.0 6e-23 82.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIW83387.1 - 1.3e-11 45.0 0.0 3e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIW83387.1 - 3.7e-10 39.1 0.0 8.4e-10 37.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIW83387.1 - 0.0024 17.4 0.4 0.0075 15.8 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FAD_binding_3 PF01494.14 EIW83388.1 - 1.4e-20 73.6 0.1 6.2e-20 71.5 0.1 1.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIW83388.1 - 1.5e-11 43.8 0.1 0.00011 21.2 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EIW83388.1 - 7.8e-06 24.6 0.0 0.0034 15.9 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 EIW83388.1 - 1.2e-05 24.3 0.9 2.4e-05 23.3 0.3 1.7 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EIW83388.1 - 1.2e-05 25.2 0.5 3.8e-05 23.6 0.4 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW83388.1 - 0.00011 22.3 0.0 0.0002 21.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW83388.1 - 0.00014 21.7 0.5 0.00047 20.1 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIW83388.1 - 0.00018 20.5 0.1 0.0069 15.3 0.1 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EIW83388.1 - 0.00099 18.9 0.3 1.5 8.6 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 EIW83388.1 - 0.0025 18.1 0.1 0.21 12.0 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW83388.1 - 0.003 16.6 0.1 0.0053 15.8 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EIW83388.1 - 0.007 15.5 1.8 0.017 14.2 1.3 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EIW83388.1 - 0.015 14.2 0.1 0.023 13.5 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EIW83388.1 - 0.035 12.7 0.0 1.3 7.5 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase 3HCDH_N PF02737.13 EIW83388.1 - 0.13 11.8 0.0 0.22 11.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EIW83388.1 - 0.17 11.2 0.1 0.27 10.5 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.14 EIW83389.1 - 8.7e-20 71.0 0.0 2.6e-19 69.5 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIW83389.1 - 2.3e-13 49.8 0.1 1.7e-05 23.8 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIW83389.1 - 1.8e-06 28.1 0.0 3.2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW83389.1 - 9.1e-06 25.6 0.1 2.6e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIW83389.1 - 1.8e-05 23.8 0.1 0.0046 15.9 0.2 2.5 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EIW83389.1 - 1.8e-05 24.7 0.3 4.6e-05 23.3 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW83389.1 - 3.5e-05 22.8 0.7 7.3e-05 21.7 0.5 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EIW83389.1 - 6.4e-05 21.6 0.1 0.0077 14.7 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.22 EIW83389.1 - 0.0002 21.7 0.0 0.0028 18.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EIW83389.1 - 0.00037 19.6 0.5 0.11 11.5 0.0 2.6 2 1 1 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EIW83389.1 - 0.00046 19.9 0.1 0.47 10.2 0.1 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding GIDA PF01134.17 EIW83389.1 - 0.00085 18.2 0.2 0.0014 17.5 0.2 1.5 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EIW83389.1 - 0.0018 17.4 0.6 0.0046 16.0 0.4 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EIW83389.1 - 0.011 14.8 0.1 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family UDPG_MGDP_dh_N PF03721.9 EIW83389.1 - 0.16 11.3 0.1 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain G-alpha PF00503.15 EIW83390.1 - 4.1e-115 384.5 0.0 4.9e-115 384.3 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIW83390.1 - 2.8e-11 42.9 1.4 2.7e-07 30.0 0.0 3.1 2 1 1 3 3 3 2 ADP-ribosylation factor family AAA_29 PF13555.1 EIW83390.1 - 0.066 12.7 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Terpene_synth_C PF03936.11 EIW83393.1 - 0.0014 17.8 0.0 0.0018 17.5 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain NIPSNAP PF07978.8 EIW83393.1 - 0.039 13.9 0.5 0.092 12.7 0.0 1.8 2 0 0 2 2 2 0 NIPSNAP F-box-like PF12937.2 EIW83394.1 - 0.00073 19.2 0.0 0.0042 16.7 0.0 2.4 1 0 0 1 1 1 1 F-box-like DUF3844 PF12955.2 EIW83395.1 - 4.2e-29 100.6 6.1 6.1e-29 100.1 4.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) F-box-like PF12937.2 EIW83396.1 - 0.01 15.5 0.1 0.04 13.6 0.1 2.1 1 1 0 1 1 1 0 F-box-like F-box-like PF12937.2 EIW83397.1 - 0.032 13.9 0.1 0.085 12.5 0.1 1.7 1 0 0 1 1 1 0 F-box-like Glyco_hydro_18 PF00704.23 EIW83398.1 - 1.2e-77 261.6 0.0 1.6e-77 261.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Methyltransf_11 PF08241.7 EIW83399.1 - 1.3e-13 51.1 0.0 2.2e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW83399.1 - 2.3e-12 46.9 0.0 3.3e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW83399.1 - 3.1e-10 40.6 0.0 4.5e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW83399.1 - 3.6e-10 40.1 0.0 7.4e-10 39.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW83399.1 - 3.5e-08 33.1 0.0 4.5e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW83399.1 - 2.9e-07 30.8 0.0 4.7e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW83399.1 - 0.00023 21.1 0.0 0.00047 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW83399.1 - 0.013 14.5 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EIW83399.1 - 0.018 14.1 0.0 0.025 13.6 0.0 1.1 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Spc7_N PF15402.1 EIW83401.1 - 0.1 10.6 0.0 0.13 10.2 0.0 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 Voltage_CLC PF00654.15 EIW83402.1 - 2.2e-90 303.2 35.2 3e-90 302.8 24.4 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 EIW83402.1 - 9.6e-06 25.2 0.5 0.00022 20.9 0.0 2.7 3 0 0 3 3 3 1 CBS domain DUF663 PF04950.7 EIW83404.1 - 6.2e-90 301.1 0.0 2.2e-89 299.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EIW83404.1 - 1.3e-21 75.8 0.0 2.8e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Gti1_Pac2 PF09729.4 EIW83406.1 - 3.9e-19 69.1 0.0 4e-16 59.3 0.0 2.4 1 1 1 2 2 2 2 Gti1/Pac2 family Gti1_Pac2 PF09729.4 EIW83408.1 - 1.6e-26 93.1 0.2 9e-22 77.7 0.0 2.1 1 1 1 2 2 2 2 Gti1/Pac2 family tRNA-synt_1e PF01406.14 EIW83409.1 - 2.2e-125 417.7 0.0 4e-125 416.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EIW83409.1 - 1.4e-08 33.8 0.5 1.8e-05 23.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EIW83409.1 - 1.1e-05 23.6 0.0 0.0013 16.8 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.6 EIW83409.1 - 0.0027 17.9 0.2 0.0074 16.5 0.0 1.9 2 0 0 2 2 2 1 DALR domain GLTP PF08718.6 EIW83410.1 - 2.5e-39 134.7 0.0 3.1e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) Codanin-1_C PF15296.1 EIW83410.1 - 0.066 13.0 0.0 0.098 12.5 0.0 1.4 1 1 0 1 1 1 0 Codanin-1 C-terminus F-box-like PF12937.2 EIW83411.1 - 0.0012 18.5 0.4 0.0025 17.4 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW83411.1 - 0.013 15.0 0.2 0.031 13.9 0.1 1.6 1 0 0 1 1 1 0 F-box domain FAD_binding_3 PF01494.14 EIW83412.1 - 6.5e-19 68.1 0.0 6e-18 65.0 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIW83412.1 - 4.7e-13 48.7 0.4 7.2e-07 28.4 0.2 2.8 2 1 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIW83412.1 - 1.5e-07 30.7 0.0 0.0017 17.3 0.1 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 EIW83412.1 - 2e-07 30.9 0.1 6.2e-07 29.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIW83412.1 - 8.3e-06 24.8 0.7 8.3e-06 24.8 0.5 2.1 2 1 1 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 EIW83412.1 - 2.6e-05 24.1 0.2 4.5e-05 23.4 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW83412.1 - 3.3e-05 22.5 0.0 0.00054 18.5 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EIW83412.1 - 0.00024 20.2 0.1 0.00089 18.4 0.0 1.8 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 EIW83412.1 - 0.00042 19.2 0.1 0.00059 18.8 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EIW83412.1 - 0.0016 18.1 0.1 0.04 13.7 0.1 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EIW83412.1 - 0.0017 18.4 0.0 0.0024 17.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIW83412.1 - 0.0027 16.8 0.7 0.0072 15.4 0.5 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW83412.1 - 0.022 15.1 0.0 0.13 12.7 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EIW83412.1 - 0.029 14.0 0.2 0.046 13.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Rossmann-like PF10727.4 EIW83412.1 - 0.033 13.9 0.2 0.056 13.1 0.1 1.4 1 0 0 1 1 1 0 Rossmann-like domain Amino_oxidase PF01593.19 EIW83412.1 - 0.045 12.8 0.1 0.32 9.9 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase AlaDh_PNT_C PF01262.16 EIW83412.1 - 0.11 12.0 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 EIW83412.1 - 0.12 10.9 0.0 0.74 8.3 0.0 2.1 3 0 0 3 3 3 0 Tryptophan halogenase ApbA PF02558.11 EIW83412.1 - 0.19 11.1 0.1 0.37 10.2 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Bax1-I PF01027.15 EIW83414.1 - 0.036 13.6 7.1 0.029 13.9 4.0 1.6 1 1 1 2 2 2 0 Inhibitor of apoptosis-promoting Bax1 Bax1-I PF01027.15 EIW83416.1 - 2.5e-45 154.5 26.1 3e-45 154.3 18.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4131 PF13567.1 EIW83416.1 - 3.1 7.1 14.6 0.12 11.7 3.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) CpXC PF14353.1 EIW83417.1 - 0.026 14.4 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 CpXC protein STE3 PF02076.10 EIW83418.1 - 9.3e-83 277.5 16.8 1.1e-82 277.2 11.6 1.1 1 0 0 1 1 1 1 Pheromone A receptor Mit_KHE1 PF10173.4 EIW83418.1 - 0.11 12.3 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related SKG6 PF08693.5 EIW83418.1 - 6 6.2 5.9 1.9 7.8 0.5 2.7 3 0 0 3 3 3 0 Transmembrane alpha-helix domain Peptidase_A4 PF01828.12 EIW83421.1 - 4.4e-70 234.9 12.7 5.8e-70 234.5 8.8 1.2 1 0 0 1 1 1 1 Peptidase A4 family CBM_X2 PF03442.9 EIW83421.1 - 0.047 13.5 0.7 0.13 12.0 0.5 1.8 1 0 0 1 1 1 0 Carbohydrate binding domain X2 Autophagy_N PF03986.8 EIW83424.1 - 3.5e-45 153.3 0.0 5.4e-45 152.7 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EIW83424.1 - 1.4e-24 86.0 0.2 2.5e-24 85.1 0.1 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EIW83424.1 - 4e-12 45.0 3.2 7.1e-12 44.2 2.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Peptidase_A4 PF01828.12 EIW83425.1 - 3.8e-72 241.7 14.3 4.4e-72 241.4 9.9 1.0 1 0 0 1 1 1 1 Peptidase A4 family C6 PF01681.12 EIW83425.1 - 2.2 8.4 7.0 0.75 9.8 0.7 2.5 1 1 1 2 2 2 0 C6 domain FAD_binding_3 PF01494.14 EIW83427.1 - 2.1e-84 283.6 0.0 2.8e-84 283.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EIW83427.1 - 3.9e-33 114.4 0.0 8.4e-33 113.3 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 EIW83427.1 - 1.6e-07 30.1 0.4 3.1e-07 29.2 0.3 1.4 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EIW83427.1 - 7.8e-07 28.2 1.2 1.7e-06 27.1 0.8 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIW83427.1 - 2.1e-06 27.6 0.1 6.2e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIW83427.1 - 6.7e-06 26.1 1.1 3.4e-05 23.8 0.2 2.4 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIW83427.1 - 9.7e-06 24.9 0.1 1.4e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EIW83427.1 - 1e-05 24.6 0.7 4.6e-05 22.4 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIW83427.1 - 0.00013 21.0 0.4 0.00022 20.2 0.3 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 EIW83427.1 - 0.00017 21.9 0.1 0.00052 20.3 0.1 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW83427.1 - 0.00032 19.8 0.1 0.00072 18.7 0.1 1.5 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EIW83427.1 - 0.00043 19.2 0.3 0.0011 17.8 0.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A ApbA PF02558.11 EIW83427.1 - 0.0013 18.1 0.4 0.052 12.9 0.0 2.8 3 0 0 3 3 3 1 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 EIW83427.1 - 0.0023 16.6 0.0 0.004 15.8 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase 3HCDH_N PF02737.13 EIW83427.1 - 0.0061 16.2 0.1 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EIW83427.1 - 0.0088 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.1 EIW83427.1 - 0.0093 16.0 0.1 0.022 14.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIW83427.1 - 0.01 15.6 0.1 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding XdhC_C PF13478.1 EIW83427.1 - 0.01 16.1 0.0 0.049 13.9 0.0 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain TrkA_N PF02254.13 EIW83427.1 - 0.018 15.0 0.1 0.051 13.5 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain CPSase_L_chain PF00289.17 EIW83427.1 - 0.024 14.7 0.1 2.2 8.4 0.0 2.6 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain AlaDh_PNT_C PF01262.16 EIW83427.1 - 0.047 13.2 0.1 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ThiF PF00899.16 EIW83427.1 - 0.072 12.9 0.3 0.15 11.8 0.2 1.5 1 0 0 1 1 1 0 ThiF family FAD_binding_3 PF01494.14 EIW83429.1 - 1.2e-82 277.8 0.0 1.6e-82 277.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EIW83429.1 - 1.3e-28 99.7 0.0 2.4e-28 98.8 0.0 1.5 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 EIW83429.1 - 1.4e-07 30.3 0.8 2.5e-07 29.5 0.5 1.3 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 EIW83429.1 - 3.4e-07 30.1 0.4 9e-07 28.8 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIW83429.1 - 1.3e-06 28.7 0.1 8.4e-05 22.9 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIW83429.1 - 2.7e-06 26.7 0.0 4.3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EIW83429.1 - 2.7e-06 26.5 0.0 6.3e-06 25.3 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW83429.1 - 4e-06 25.9 2.2 7.4e-06 25.0 1.0 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EIW83429.1 - 4.9e-06 26.5 0.0 1.2e-05 25.2 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW83429.1 - 6.9e-05 22.0 0.2 0.00011 21.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EIW83429.1 - 0.00015 20.7 0.2 0.00034 19.6 0.2 1.6 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EIW83429.1 - 0.0002 20.4 0.4 0.00037 19.5 0.3 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EIW83429.1 - 0.00023 19.9 0.0 0.00044 19.0 0.0 1.4 1 0 0 1 1 1 1 Tryptophan halogenase 3HCDH_N PF02737.13 EIW83429.1 - 0.00088 18.9 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EIW83429.1 - 0.0029 17.7 0.0 0.005 16.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EIW83429.1 - 0.0035 16.2 0.0 0.0056 15.5 0.0 1.3 1 0 0 1 1 1 1 Squalene epoxidase NAD_binding_9 PF13454.1 EIW83429.1 - 0.012 15.4 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding XdhC_C PF13478.1 EIW83429.1 - 0.013 15.8 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain ThiF PF00899.16 EIW83429.1 - 0.014 15.2 0.2 0.029 14.2 0.1 1.5 1 0 0 1 1 1 0 ThiF family AlaDh_PNT_C PF01262.16 EIW83429.1 - 0.014 14.9 0.1 0.041 13.4 0.0 1.8 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 EIW83429.1 - 0.024 14.0 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 EIW83429.1 - 0.052 12.9 0.1 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EIW83429.1 - 0.097 12.7 0.3 0.41 10.7 0.1 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EIW83429.1 - 0.11 12.7 0.1 0.49 10.6 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding TrkA_N PF02254.13 EIW83429.1 - 0.12 12.3 0.0 0.41 10.6 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain F-box-like PF12937.2 EIW83430.1 - 0.0053 16.4 0.0 0.016 14.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like FAM212 PF15342.1 EIW83430.1 - 0.048 13.2 0.1 0.23 11.0 0.0 2.2 1 0 0 1 1 1 0 FAM212 family Terpene_synth_C PF03936.11 EIW83431.1 - 0.0011 18.2 0.0 0.0016 17.7 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain APH PF01636.18 EIW83432.1 - 0.0015 18.2 0.0 0.0052 16.5 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIW83432.1 - 0.031 13.8 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Muskelin_N PF06588.6 EIW83433.1 - 0.14 11.8 0.0 0.19 11.3 0.0 1.1 1 0 0 1 1 1 0 Muskelin N-terminus Pkinase PF00069.20 EIW83434.1 - 4.1e-09 35.9 0.0 8.1e-07 28.4 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW83434.1 - 0.0026 16.8 0.0 0.0091 15.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase DUF1177 PF06675.6 EIW83435.1 - 0.055 12.0 0.0 0.086 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1177) BBIP10 PF14777.1 EIW83435.1 - 0.055 12.8 1.4 0.099 12.0 1.0 1.4 1 0 0 1 1 1 0 Cilia BBSome complex subunit 10 Pkinase PF00069.20 EIW83437.1 - 3.4e-11 42.7 0.0 2.8e-09 36.5 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW83437.1 - 0.00033 19.8 0.0 0.0011 18.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EIW83440.1 - 2.2e-11 43.4 0.0 9.3e-09 34.8 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW83440.1 - 0.00073 18.6 0.0 0.0091 15.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pyr_redox_3 PF13738.1 EIW83441.1 - 7.4e-26 91.4 0.0 1.2e-24 87.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIW83441.1 - 5.6e-22 77.6 0.0 2.2e-21 75.6 0.0 2.0 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EIW83441.1 - 1.8e-16 60.0 0.1 3.7e-11 42.5 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EIW83441.1 - 2.3e-14 53.7 0.0 2.3e-12 47.2 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW83441.1 - 2.5e-07 30.9 0.2 0.0049 17.2 0.1 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EIW83441.1 - 5e-06 25.7 0.0 0.0013 17.8 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EIW83441.1 - 0.00019 21.1 0.1 0.52 9.9 0.0 2.4 2 1 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EIW83441.1 - 0.0017 18.3 0.1 0.036 14.0 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EIW83441.1 - 0.0019 17.3 0.0 0.023 13.7 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EIW83441.1 - 0.0033 16.3 0.3 0.036 12.9 0.1 2.4 3 0 0 3 3 3 1 Glucose inhibited division protein A Shikimate_DH PF01488.15 EIW83441.1 - 0.024 14.7 0.0 12 6.0 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.16 EIW83441.1 - 0.057 12.9 0.3 0.23 11.0 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EIW83441.1 - 0.059 13.6 0.1 31 4.9 0.0 3.0 4 0 0 4 4 3 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EIW83441.1 - 0.068 12.0 0.1 0.21 10.4 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein ThiF PF00899.16 EIW83441.1 - 0.07 12.9 0.2 1.7 8.4 0.0 3.0 3 1 0 3 3 3 0 ThiF family TrkA_N PF02254.13 EIW83441.1 - 0.073 13.0 0.1 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Thi4 PF01946.12 EIW83441.1 - 0.089 11.8 0.0 1.8 7.6 0.0 2.4 3 0 0 3 3 3 0 Thi4 family NAD_binding_9 PF13454.1 EIW83441.1 - 0.14 11.9 0.8 9.4 5.9 0.0 3.0 2 1 1 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EIW83441.1 - 0.15 10.4 0.1 1 7.7 0.0 2.2 3 0 0 3 3 3 0 HI0933-like protein UDPG_MGDP_dh_N PF03721.9 EIW83441.1 - 0.16 11.3 0.0 0.29 10.4 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DAO PF01266.19 EIW83441.1 - 0.35 9.7 4.8 1.4 7.7 0.7 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EIW83444.1 - 1.1e-80 271.3 0.0 1.4e-80 270.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EIW83444.1 - 1.1e-31 109.7 0.1 3.1e-31 108.2 0.0 1.8 2 0 0 2 2 1 1 Phenol hydroxylase, C-terminal dimerisation domain HI0933_like PF03486.9 EIW83444.1 - 6.2e-07 28.2 0.7 1e-06 27.5 0.5 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EIW83444.1 - 1.9e-05 23.7 2.4 3.6e-05 22.7 1.7 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIW83444.1 - 6.5e-05 22.8 0.2 0.00017 21.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIW83444.1 - 0.00012 21.2 0.2 0.00024 20.2 0.2 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EIW83444.1 - 0.00013 21.9 0.1 0.00038 20.3 0.1 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW83444.1 - 0.00016 20.7 0.3 0.00034 19.6 0.2 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EIW83444.1 - 0.00084 18.5 0.0 0.0012 17.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIW83444.1 - 0.0014 17.6 0.8 0.0014 17.6 0.5 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 EIW83444.1 - 0.0033 16.3 0.9 0.007 15.2 0.6 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EIW83444.1 - 0.0034 17.7 0.1 0.018 15.4 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW83444.1 - 0.02 14.9 0.1 0.035 14.1 0.1 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EIW83444.1 - 0.034 13.9 0.5 0.081 12.7 0.4 1.6 1 0 0 1 1 1 0 ThiF family 3HCDH_N PF02737.13 EIW83444.1 - 0.046 13.3 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CPSase_L_chain PF00289.17 EIW83444.1 - 0.047 13.8 0.2 14 5.8 0.1 2.4 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Trp_halogenase PF04820.9 EIW83444.1 - 0.086 11.4 0.5 0.18 10.4 0.4 1.5 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EIW83444.1 - 0.1 12.3 0.3 0.21 11.3 0.2 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 EIW83444.1 - 0.15 11.6 0.1 0.31 10.5 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.5 EIW83444.1 - 0.15 10.8 0.0 0.25 10.1 0.0 1.4 1 0 0 1 1 1 0 Squalene epoxidase Methyltransf_25 PF13649.1 EIW83445.1 - 1.4e-06 28.5 0.0 4.6e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Catalase-rel PF06628.7 EIW83445.1 - 0.00033 20.4 0.0 0.00071 19.3 0.0 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive Terpene_synth_C PF03936.11 EIW83446.1 - 9.2e-05 21.7 0.0 0.00012 21.4 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Toxin_8 PF07365.7 EIW83446.1 - 0.021 14.7 0.0 4.3 7.3 0.0 2.5 2 0 0 2 2 2 0 Alpha conotoxin precursor LRR_4 PF12799.2 EIW83447.1 - 4.8e-18 64.3 5.6 4.4e-08 32.5 0.0 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) Exo_endo_phos PF03372.18 EIW83447.1 - 2.6e-17 63.5 4.9 4.5e-16 59.5 3.4 2.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_8 PF13855.1 EIW83447.1 - 1.4e-14 53.5 15.4 2e-09 37.0 2.5 2.3 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 EIW83447.1 - 2.2e-08 33.0 3.1 0.15 12.2 0.0 4.6 5 0 0 5 5 5 3 Leucine Rich Repeat LRR_7 PF13504.1 EIW83447.1 - 1.5e-06 27.4 6.2 1.3 9.5 0.0 4.8 5 0 0 5 5 5 3 Leucine rich repeat LRR_6 PF13516.1 EIW83447.1 - 0.0019 18.0 2.4 22 5.5 0.0 4.4 4 0 0 4 4 4 1 Leucine Rich repeat GHMP_kinases_N PF00288.21 EIW83448.1 - 3.3e-07 30.2 2.3 3.3e-07 30.2 1.6 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain COBRA PF04833.10 EIW83448.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 COBRA-like protein Muskelin_N PF06588.6 EIW83449.1 - 1.2e-24 87.0 0.0 1.8e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Muskelin N-terminus Kelch_5 PF13854.1 EIW83449.1 - 1e-22 79.6 1.8 4.1e-08 32.9 0.1 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_4 PF13418.1 EIW83449.1 - 3.3e-20 71.6 16.4 2.9e-08 33.3 0.3 6.1 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_3 PF13415.1 EIW83449.1 - 6.5e-19 67.5 24.9 1.2e-08 34.8 0.1 8.7 9 0 0 9 9 9 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EIW83449.1 - 4.3e-14 51.9 7.1 9e-05 22.4 0.0 6.7 7 0 0 7 7 7 3 Kelch motif Kelch_1 PF01344.20 EIW83449.1 - 3.7e-12 45.5 2.3 8.2e-07 28.4 0.2 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 EIW83449.1 - 2.8e-06 26.8 3.0 2.4e-05 23.8 0.6 3.4 2 0 0 2 2 2 1 Kelch motif DJ-1_PfpI PF01965.19 EIW83450.1 - 1.6e-24 86.0 0.1 2.6e-24 85.3 0.1 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EIW83450.1 - 1e-09 37.7 0.1 2e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family Prefoldin_2 PF01920.15 EIW83451.1 - 5.6e-22 77.5 12.1 6.7e-22 77.2 8.4 1.1 1 0 0 1 1 1 1 Prefoldin subunit BLOC1_2 PF10046.4 EIW83451.1 - 0.0056 16.7 8.1 0.035 14.2 1.7 2.1 2 0 0 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_11 PF13414.1 EIW83451.1 - 0.0096 15.5 0.1 0.018 14.6 0.0 1.4 1 0 0 1 1 1 1 TPR repeat DivIC PF04977.10 EIW83451.1 - 0.012 15.0 11.9 0.12 11.8 0.8 2.2 1 1 0 2 2 2 0 Septum formation initiator TPR_MLP1_2 PF07926.7 EIW83451.1 - 0.015 14.9 10.3 0.036 13.8 7.2 1.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Scaffolding_pro PF11418.3 EIW83451.1 - 0.054 13.8 0.8 0.054 13.8 0.5 2.1 1 1 1 2 2 2 0 Phi29 scaffolding protein PEP-utilisers_N PF05524.8 EIW83451.1 - 0.055 13.2 1.1 0.28 10.9 0.0 2.0 2 0 0 2 2 2 0 PEP-utilising enzyme, N-terminal Tox-URI2 PF15653.1 EIW83451.1 - 0.058 13.5 0.2 0.16 12.1 0.0 1.8 1 1 1 2 2 2 0 URI fold toxin 2 Prefoldin PF02996.12 EIW83451.1 - 0.061 12.9 9.5 0.33 10.6 0.9 2.2 1 1 0 2 2 2 0 Prefoldin subunit Seryl_tRNA_N PF02403.17 EIW83451.1 - 0.077 13.0 8.1 0.97 9.4 0.4 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Katanin_con80 PF13925.1 EIW83451.1 - 0.08 12.6 2.5 0.12 12.1 0.2 1.9 2 0 0 2 2 2 0 con80 domain of Katanin DUF1788 PF08747.6 EIW83451.1 - 0.12 12.2 0.4 0.18 11.6 0.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF1788) DUF342 PF03961.8 EIW83451.1 - 0.13 10.6 6.3 0.16 10.3 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Pox_F11 PF04943.7 EIW83451.1 - 0.13 11.0 1.8 0.14 10.9 1.3 1.0 1 0 0 1 1 1 0 Poxvirus F11 protein DASH_Dam1 PF08653.5 EIW83451.1 - 0.16 11.7 1.7 12 5.7 0.0 2.4 2 0 0 2 2 2 0 DASH complex subunit Dam1 DUF948 PF06103.6 EIW83451.1 - 0.24 11.3 1.2 12 5.8 0.2 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Spectrin PF00435.16 EIW83451.1 - 0.25 11.6 8.5 0.39 11.0 5.7 1.5 1 1 0 1 1 1 0 Spectrin repeat Mnd1 PF03962.10 EIW83451.1 - 0.28 10.8 8.5 1 9.0 5.6 1.9 1 1 1 2 2 2 0 Mnd1 family DUF4140 PF13600.1 EIW83451.1 - 0.28 11.6 8.5 2.6 8.5 0.6 2.1 1 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) FlxA PF14282.1 EIW83451.1 - 0.34 10.8 7.6 0.86 9.5 0.4 2.3 2 0 0 2 2 2 0 FlxA-like protein MtrG PF04210.8 EIW83451.1 - 0.43 10.2 3.8 0.77 9.4 0.3 2.6 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G ORF6C PF10552.4 EIW83451.1 - 0.44 10.2 8.2 4 7.2 0.3 2.4 2 1 0 2 2 2 0 ORF6C domain FlaC_arch PF05377.6 EIW83451.1 - 0.44 10.4 7.3 1.9 8.4 0.1 2.7 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Phage_GP20 PF06810.6 EIW83451.1 - 0.59 9.5 11.6 0.51 9.7 0.9 2.1 2 0 0 2 2 2 0 Phage minor structural protein GP20 HALZ PF02183.13 EIW83451.1 - 0.67 9.7 13.3 1.1 8.9 3.0 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper Spc7 PF08317.6 EIW83451.1 - 0.72 8.4 12.1 1.3 7.5 8.4 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein DASH_Dad3 PF08656.5 EIW83451.1 - 0.84 9.3 5.8 1.6 8.5 0.6 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad3 DUF2681 PF10883.3 EIW83451.1 - 0.85 9.8 7.2 0.97 9.6 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2681) TMF_DNA_bd PF12329.3 EIW83451.1 - 0.92 9.3 13.8 0.26 11.0 1.8 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Sipho_Gp157 PF05565.6 EIW83451.1 - 1 8.9 10.7 1.1 8.8 0.3 2.1 2 0 0 2 2 2 0 Siphovirus Gp157 Fib_alpha PF08702.5 EIW83451.1 - 1 9.4 5.1 1.8 8.7 3.5 1.3 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family bZIP_1 PF00170.16 EIW83451.1 - 1 9.3 14.8 1.6 8.7 2.9 2.5 2 1 0 2 2 2 0 bZIP transcription factor TBPIP PF07106.8 EIW83451.1 - 1.2 8.6 11.8 1.5 8.3 1.5 2.1 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Syntaxin PF00804.20 EIW83451.1 - 1.4 9.1 8.3 3.3 7.9 5.8 1.6 1 1 0 1 1 1 0 Syntaxin DUF2312 PF10073.4 EIW83451.1 - 1.4 8.3 5.9 1.1 8.6 1.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Kinetocho_Slk19 PF12709.2 EIW83451.1 - 1.6 8.8 10.3 4.8 7.3 1.7 2.3 2 0 0 2 2 2 0 Central kinetochore-associated UPF0449 PF15136.1 EIW83451.1 - 1.8 8.7 8.3 3.3 7.9 0.8 2.2 1 1 1 2 2 2 0 Uncharacterised protein family UPF0449 V_ATPase_I PF01496.14 EIW83451.1 - 2.1 6.1 6.9 2.7 5.7 4.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_23 PF13476.1 EIW83451.1 - 2.4 8.4 11.7 3.1 8.0 8.1 1.2 1 0 0 1 1 1 0 AAA domain NYD-SP28 PF14772.1 EIW83451.1 - 2.5 8.2 12.6 1.8 8.7 3.6 2.1 2 0 0 2 2 2 0 Sperm tail DUF2951 PF11166.3 EIW83451.1 - 2.7 7.9 10.9 0.24 11.2 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2951) DUF607 PF04678.8 EIW83451.1 - 2.8 7.8 6.9 4.3 7.2 0.8 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF607 DUF972 PF06156.8 EIW83451.1 - 3.1 8.1 10.3 6 7.2 0.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Sec34 PF04136.10 EIW83451.1 - 4.1 7.1 7.9 1.3 8.7 0.7 2.1 1 1 0 2 2 2 0 Sec34-like family DUF4047 PF13256.1 EIW83451.1 - 4.1 7.3 6.8 2.3 8.2 1.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) XhlA PF10779.4 EIW83451.1 - 4.4 7.2 8.5 8 6.4 1.6 2.4 2 0 0 2 2 2 0 Haemolysin XhlA DUF16 PF01519.11 EIW83451.1 - 4.5 7.5 8.8 7.1 6.9 6.1 1.4 1 1 0 1 1 1 0 Protein of unknown function DUF16 Occludin_ELL PF07303.8 EIW83451.1 - 4.6 8.0 6.9 21 5.9 0.7 2.2 1 1 1 2 2 2 0 Occludin homology domain Viral_P18 PF04521.8 EIW83451.1 - 4.8 6.6 7.7 4.1 6.8 0.7 2.1 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein IncA PF04156.9 EIW83451.1 - 5.6 6.5 16.6 18 4.8 11.5 1.7 1 1 0 1 1 1 0 IncA protein Suppressor_APC PF11414.3 EIW83451.1 - 9.8 6.0 10.2 1.2 8.9 0.6 2.7 2 1 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Pyridoxal_deC PF00282.14 EIW83452.1 - 4e-15 55.1 0.0 9.9e-15 53.8 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EIW83452.1 - 1e-09 37.6 0.0 1.2e-06 27.5 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EIW83452.1 - 1.1e-05 24.6 0.1 1.7e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Arrestin_N PF00339.24 EIW83454.1 - 3.6e-14 52.8 0.0 3e-11 43.3 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EIW83454.1 - 1.1e-09 38.5 0.1 3.6e-08 33.5 0.1 2.7 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 EIW83454.1 - 0.0006 19.3 0.0 0.0013 18.2 0.0 1.5 1 0 0 1 1 1 1 Arrestin_N terminal like Sugar_tr PF00083.19 EIW83455.1 - 3e-84 283.1 21.6 3.5e-84 282.9 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW83455.1 - 1.4e-26 93.0 39.8 2.7e-23 82.2 13.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIW83455.1 - 1.9e-07 29.8 19.4 4.4e-05 22.0 1.4 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein Glyco_hydro_2 PF00703.16 EIW83456.1 - 0.013 15.9 0.1 0.032 14.6 0.1 1.7 1 0 0 1 1 1 0 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 EIW83456.1 - 0.21 10.4 0.1 0.43 9.4 0.1 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Pkinase PF00069.20 EIW83457.1 - 8.3e-13 48.0 0.0 2.2e-12 46.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW83457.1 - 0.00038 19.6 0.1 0.0016 17.5 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Uds1 PF15456.1 EIW83458.1 - 0.0011 18.9 2.3 0.0021 18.0 1.3 1.7 1 1 0 1 1 1 1 Up-regulated During Septation DUF4391 PF14335.1 EIW83458.1 - 0.012 15.0 0.1 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4391) p450 PF00067.17 EIW83459.1 - 6.6e-61 206.2 0.0 3.8e-60 203.7 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 EIW83460.1 - 4.2e-68 229.3 0.1 6.6e-68 228.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW83460.1 - 4.8e-39 133.9 0.1 1.5e-38 132.3 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EIW83460.1 - 4.2e-16 58.8 0.3 1.1e-15 57.4 0.2 1.8 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EIW83460.1 - 2e-07 30.2 0.0 2.7e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW83460.1 - 6.3e-05 22.8 0.2 0.00029 20.6 0.0 2.1 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EIW83460.1 - 0.00014 20.9 0.0 0.00027 20.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EIW83460.1 - 0.19 11.0 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 RIO1 family MFS_1 PF07690.11 EIW83462.1 - 6.2e-44 150.1 38.9 6.2e-44 150.1 27.0 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW83462.1 - 3.6e-11 42.3 8.5 3.6e-11 42.3 5.9 3.5 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 EIW83462.1 - 2.6e-05 22.5 2.9 5.5e-05 21.4 2.0 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector zf-C2H2 PF00096.21 EIW83463.1 - 3.8e-08 33.2 11.6 0.015 15.6 0.6 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW83463.1 - 3.9e-05 23.6 14.8 0.12 12.7 0.1 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIW83463.1 - 0.0012 19.0 0.2 0.0012 19.0 0.1 3.1 3 0 0 3 3 3 1 Zinc-finger double domain HMG_box PF00505.14 EIW83464.1 - 0.0034 17.6 0.1 0.0045 17.2 0.1 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box NUDIX PF00293.23 EIW83465.1 - 4.6e-16 58.6 0.0 8.1e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 EIW83465.1 - 1.4e-09 38.1 0.0 5e-09 36.3 0.0 2.0 1 1 0 1 1 1 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EIW83465.1 - 2e-05 24.0 1.3 3.6e-05 23.1 0.9 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain DUF4131 PF13567.1 EIW83466.1 - 2.7 7.3 9.3 10 5.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Mito_carr PF00153.22 EIW83468.1 - 1.6e-63 210.4 3.9 1.5e-22 79.1 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein NAD_binding_4 PF07993.7 EIW83469.1 - 2.2e-37 128.3 0.0 4.2e-37 127.4 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EIW83469.1 - 4.9e-31 107.5 0.0 7e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EIW83469.1 - 4.8e-11 42.5 0.0 8.8e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW83469.1 - 7.4e-07 29.3 0.0 4.8e-05 23.4 0.0 2.6 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIW83469.1 - 7.8e-05 21.5 0.0 0.00016 20.4 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EIW83469.1 - 7.8e-05 22.6 1.6 0.00017 21.5 0.1 2.3 2 1 0 2 2 2 1 short chain dehydrogenase PP-binding PF00550.20 EIW83469.1 - 0.0011 19.1 0.1 0.0039 17.4 0.0 2.0 1 1 0 1 1 1 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 EIW83469.1 - 0.016 14.1 0.0 0.44 9.4 0.0 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain KR PF08659.5 EIW83469.1 - 0.049 13.2 0.1 0.24 11.0 0.1 2.1 1 1 0 1 1 1 0 KR domain Glyco_hydro_43 PF04616.9 EIW83470.1 - 8.1e-36 123.5 0.1 9.5e-36 123.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_43 PF04616.9 EIW83471.1 - 3.4e-29 101.8 0.0 1.1e-28 100.1 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 BNR PF02012.15 EIW83471.1 - 0.2 11.6 5.2 0.8 9.7 0.6 3.4 3 0 0 3 3 3 0 BNR/Asp-box repeat Pyr_redox_3 PF13738.1 EIW83472.1 - 1.6e-24 87.1 0.0 2.7e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIW83472.1 - 5.9e-21 74.2 0.0 3.9e-20 71.5 0.0 2.2 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EIW83472.1 - 3.7e-13 49.1 0.2 5e-09 35.5 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EIW83472.1 - 1.2e-12 48.1 0.0 1.7e-11 44.4 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW83472.1 - 1.6e-08 34.8 0.5 0.0011 19.3 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EIW83472.1 - 4.8e-07 29.1 0.0 0.0004 19.5 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_8 PF13450.1 EIW83472.1 - 0.00015 21.7 0.0 0.00045 20.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EIW83472.1 - 0.0008 19.5 0.2 0.38 10.8 0.0 2.8 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 EIW83472.1 - 0.0012 17.8 0.0 0.0043 15.9 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EIW83472.1 - 0.0013 17.9 0.0 0.0031 16.6 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EIW83472.1 - 0.0038 16.3 0.1 0.13 11.3 0.0 2.3 2 0 0 2 2 2 1 Thi4 family 3HCDH_N PF02737.13 EIW83472.1 - 0.0053 16.4 0.3 1.9 8.0 0.0 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EIW83472.1 - 0.0055 15.2 0.0 0.057 11.8 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EIW83472.1 - 0.036 12.9 1.7 0.074 11.9 0.1 2.2 3 0 0 3 3 3 0 Glucose inhibited division protein A TrkA_N PF02254.13 EIW83472.1 - 0.044 13.7 0.1 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_2 PF00890.19 EIW83472.1 - 0.063 12.1 0.2 0.15 10.9 0.2 1.5 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 EIW83472.1 - 0.066 12.1 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein ThiF PF00899.16 EIW83472.1 - 0.072 12.9 0.1 0.41 10.4 0.0 2.1 2 0 0 2 2 2 0 ThiF family DUF659 PF04937.10 EIW83473.1 - 0.00012 21.6 0.0 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) WD40 PF00400.27 EIW83474.1 - 1.3e-07 31.2 1.8 0.09 12.6 0.0 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat TPR_14 PF13428.1 EIW83475.1 - 9.3e-26 87.9 28.0 0.0017 18.8 0.0 12.6 6 3 8 14 14 13 7 Tetratricopeptide repeat HAT PF02184.11 EIW83475.1 - 7.4e-20 70.4 53.4 8.4e-08 31.8 1.5 13.2 13 2 0 13 13 13 5 HAT (Half-A-TPR) repeat TPR_19 PF14559.1 EIW83475.1 - 1.6e-16 60.3 0.5 0.015 15.6 0.0 7.9 6 1 3 9 9 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 EIW83475.1 - 1e-15 57.8 21.8 0.0038 17.8 0.0 9.0 6 1 4 10 10 9 5 Tetratricopeptide repeat TPR_2 PF07719.12 EIW83475.1 - 1.8e-14 52.3 5.3 0.16 11.9 0.0 9.8 11 0 0 11 11 10 3 Tetratricopeptide repeat Suf PF05843.9 EIW83475.1 - 6.8e-11 42.4 7.9 0.0084 15.8 0.1 6.2 3 2 2 5 5 5 3 Suppressor of forked protein (Suf) TPR_11 PF13414.1 EIW83475.1 - 3.1e-09 36.3 0.8 0.73 9.5 0.0 6.7 5 2 3 8 8 8 2 TPR repeat TPR_7 PF13176.1 EIW83475.1 - 5.3e-09 35.2 12.4 0.19 11.6 0.0 8.9 11 0 0 11 11 10 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIW83475.1 - 7.5e-09 35.4 5.3 0.4 10.6 0.0 7.6 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIW83475.1 - 1.4e-07 31.1 0.0 0.21 11.8 0.0 5.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 EIW83475.1 - 1.8e-06 27.2 20.1 0.03 13.4 3.8 5.2 2 2 3 5 5 5 3 Tetratricopeptide repeat SNAP PF14938.1 EIW83475.1 - 2.1e-06 27.1 0.8 0.00063 18.9 0.1 3.4 4 0 0 4 4 4 1 Soluble NSF attachment protein, SNAP TPR_1 PF00515.23 EIW83475.1 - 2.4e-06 26.9 0.2 14 5.4 0.0 6.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIW83475.1 - 5.1e-05 22.7 0.0 3.8 7.5 0.0 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EIW83475.1 - 0.00069 19.3 12.9 0.045 13.5 0.5 5.5 4 3 3 7 7 6 2 U3 small nucleolar RNA-associated protein 6 Mad3_BUB1_I PF08311.7 EIW83475.1 - 0.0015 18.2 13.8 4.7 7.0 0.0 6.9 4 2 2 6 6 6 1 Mad3/BUB1 homology region 1 TPR_6 PF13174.1 EIW83475.1 - 0.0031 17.8 10.4 13 6.4 0.1 7.7 8 1 0 8 8 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIW83475.1 - 0.011 15.5 2.6 23 4.9 0.1 5.0 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat c-SKI_SMAD_bind PF08782.5 EIW83475.1 - 0.13 12.4 3.1 9.2 6.4 0.1 4.4 5 0 0 5 5 5 0 c-SKI Smad4 binding domain YlbD_coat PF14071.1 EIW83475.1 - 0.24 11.4 6.5 3.2 7.8 0.7 4.2 2 1 1 3 3 3 0 Putative coat protein Nucleoplasmin PF03066.10 EIW83475.1 - 2.2 7.7 18.6 12 5.4 0.1 2.9 2 1 0 2 2 2 0 Nucleoplasmin Pkinase PF00069.20 EIW83477.1 - 1.9e-13 50.1 0.0 1.7e-12 47.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW83477.1 - 0.00023 20.2 0.0 0.00057 19.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EIW83477.1 - 0.031 13.6 0.2 0.071 12.4 0.0 1.6 2 0 0 2 2 2 0 RIO1 family GST_C PF00043.20 EIW83478.1 - 1.3e-12 47.5 0.0 1.8e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW83478.1 - 1.3e-10 41.3 0.0 2.1e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW83478.1 - 6.4e-09 35.5 0.0 1.4e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIW83478.1 - 8e-07 29.2 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIW83478.1 - 2.2e-06 28.0 0.1 3.3e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PX PF00787.19 EIW83478.1 - 0.022 14.5 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 PX domain LRR_4 PF12799.2 EIW83482.1 - 2.2e-56 186.6 31.1 3.3e-07 29.7 0.2 12.0 9 3 2 12 12 12 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW83482.1 - 9.2e-51 169.4 33.9 8.4e-13 47.8 0.5 9.5 6 3 5 12 12 12 9 Leucine rich repeat PP2C PF00481.16 EIW83482.1 - 8.2e-39 133.5 0.0 1.6e-38 132.5 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_1 PF00560.28 EIW83482.1 - 2.3e-28 93.8 39.0 0.14 12.2 0.1 19.2 20 2 1 21 21 21 9 Leucine Rich Repeat Guanylate_cyc PF00211.15 EIW83482.1 - 2.8e-19 69.2 0.0 4.5e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain LRR_7 PF13504.1 EIW83482.1 - 2e-16 57.2 37.0 0.35 11.2 0.1 16.5 19 0 0 19 19 19 4 Leucine rich repeat LRR_6 PF13516.1 EIW83482.1 - 4.6e-09 35.4 24.6 8.3 6.8 0.0 14.7 17 0 0 17 17 17 1 Leucine Rich repeat LRR_9 PF14580.1 EIW83482.1 - 4.5e-08 32.8 7.3 0.0064 16.0 0.1 4.1 3 1 1 4 4 4 3 Leucine-rich repeat LRR_5 PF13306.1 EIW83482.1 - 0.31 10.7 0.0 34 4.1 0.0 2.6 2 0 0 2 2 2 0 Leucine rich repeats (6 copies) Mg_trans_NIPA PF05653.9 EIW83483.1 - 1.9e-85 286.4 25.8 3e-85 285.8 17.9 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 EIW83483.1 - 1.1e-06 28.7 14.0 1.1e-06 28.7 9.7 3.8 2 2 1 3 3 3 1 EamA-like transporter family EmrE PF13536.1 EIW83483.1 - 1.2e-06 28.6 6.3 1.2e-06 28.6 4.4 3.4 2 1 1 3 3 3 1 Multidrug resistance efflux transporter Pkinase PF00069.20 EIW83485.1 - 4.6e-08 32.5 0.0 8.6e-08 31.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain CDP-OH_P_tran_2 PF08009.6 EIW83487.1 - 0.034 13.8 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase 2 RVT_1 PF00078.22 EIW83488.1 - 0.08 12.2 0.0 0.24 10.7 0.0 1.7 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) YkyA PF10368.4 EIW83490.1 - 0.15 11.3 2.1 0.29 10.4 0.2 1.9 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein YqcI_YcgG PF08892.6 EIW83493.1 - 9e-05 22.1 0.0 0.00012 21.6 0.0 1.1 1 0 0 1 1 1 1 YqcI/YcgG family F-box-like PF12937.2 EIW83494.1 - 1.4e-05 24.6 0.0 3.9e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like DUF2629 PF10945.3 EIW83494.1 - 0.0038 16.5 0.4 0.027 13.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2629) F-box-like PF12937.2 EIW83495.1 - 6.7e-05 22.5 0.4 0.0088 15.7 0.0 3.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EIW83495.1 - 1 9.0 8.9 3.7 7.2 0.1 4.5 4 2 0 4 4 4 0 Leucine Rich repeats (2 copies) Glyco_hydro_2 PF00703.16 EIW83496.1 - 0.0055 17.1 0.1 0.012 16.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Zn_clus PF00172.13 EIW83497.1 - 0.00017 21.4 5.5 0.00027 20.7 3.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SPC22 PF04573.7 EIW83499.1 - 8.4e-42 142.3 0.0 9.3e-42 142.2 0.0 1.0 1 0 0 1 1 1 1 Signal peptidase subunit LRR_7 PF13504.1 EIW83500.1 - 0.062 13.5 0.2 1.1e+02 3.7 0.0 4.6 4 0 0 4 4 4 0 Leucine rich repeat Acyltransferase PF01553.16 EIW83501.1 - 4.3e-11 42.3 0.0 7.2e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase CobD_Cbib PF03186.8 EIW83501.1 - 0.29 10.1 4.5 0.1 11.6 0.8 1.8 2 0 0 2 2 2 0 CobD/Cbib protein Rep_fac_C PF08542.6 EIW83502.1 - 0.11 12.4 0.1 0.3 11.1 0.0 1.7 1 0 0 1 1 1 0 Replication factor C C-terminal domain Ribosomal_S2 PF00318.15 EIW83504.1 - 8.5e-46 155.8 0.1 1.8e-23 82.8 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 SopD PF11047.3 EIW83508.1 - 0.095 11.6 0.0 0.13 11.1 0.0 1.1 1 0 0 1 1 1 0 Salmonella outer protein D Lipase_3 PF01764.20 EIW83509.1 - 9e-31 106.3 0.0 1.3e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.15 EIW83509.1 - 0.021 15.0 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain PE-PPE PF08237.6 EIW83509.1 - 0.022 14.1 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain DUF676 PF05057.9 EIW83509.1 - 0.028 13.7 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2974 PF11187.3 EIW83509.1 - 0.029 13.7 0.1 0.098 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 EIW83509.1 - 0.042 13.6 0.0 0.056 13.1 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW83509.1 - 0.05 13.4 1.0 0.067 13.0 0.7 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family Cutinase PF01083.17 EIW83509.1 - 0.084 12.5 0.0 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 Cutinase p450 PF00067.17 EIW83510.1 - 1.9e-49 168.4 0.0 2.3e-49 168.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 API5 PF05918.6 EIW83512.1 - 1.1e-17 63.7 0.5 4.1e-17 61.9 0.0 2.1 2 0 0 2 2 2 1 Apoptosis inhibitory protein 5 (API5) HEAT_2 PF13646.1 EIW83512.1 - 0.00027 21.1 3.7 0.0017 18.5 0.1 3.3 3 0 0 3 3 3 1 HEAT repeats Adaptin_N PF01602.15 EIW83512.1 - 0.01 14.2 0.1 0.015 13.6 0.1 1.2 1 0 0 1 1 1 0 Adaptin N terminal region Peptidase_A4 PF01828.12 EIW83513.1 - 1.4e-74 249.6 14.7 1.7e-74 249.3 10.2 1.1 1 0 0 1 1 1 1 Peptidase A4 family Peptidase_C25_C PF03785.9 EIW83513.1 - 2 8.2 8.6 8.7 6.2 1.2 2.5 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain FUSC_2 PF13515.1 EIW83515.1 - 1.9e-21 76.3 11.5 1.9e-21 76.3 8.0 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 EIW83515.1 - 1.3e-12 47.0 10.7 3.7e-09 35.7 4.8 2.3 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC PF04632.7 EIW83515.1 - 9.1e-10 37.6 32.6 5.4e-07 28.4 7.3 4.0 3 2 0 3 3 3 2 Fusaric acid resistance protein family DUF2421 PF10334.4 EIW83515.1 - 7.4e-09 35.5 0.4 9.4e-07 28.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF2421) DUF939 PF06081.6 EIW83515.1 - 0.016 15.0 0.7 0.016 15.0 0.5 3.9 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF939) Methyltransf_11 PF08241.7 EIW83517.1 - 8.4e-09 35.8 0.0 1.7e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW83517.1 - 1.5e-07 31.2 0.0 2.3e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW83517.1 - 2e-07 30.7 0.0 5e-07 29.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW83517.1 - 1.1e-06 28.9 0.0 2.2e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW83517.1 - 2.3e-06 26.9 0.0 8e-06 25.1 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EIW83517.1 - 3.8e-06 27.3 0.0 1.2e-05 25.6 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIW83517.1 - 0.0011 18.6 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_18 PF12847.2 EIW83517.1 - 0.0019 18.7 0.0 0.017 15.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EIW83517.1 - 0.0029 17.6 0.0 0.015 15.2 0.0 1.9 1 1 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EIW83517.1 - 0.13 12.2 0.0 0.66 10.0 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain CoA_binding_2 PF13380.1 EIW83518.1 - 3.5e-08 33.6 0.0 5.2e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 CoA binding domain DUF2866 PF11065.3 EIW83518.1 - 0.039 13.8 0.4 2 8.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2866) DUF2874 PF11396.3 EIW83518.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2874) PALP PF00291.20 EIW83519.1 - 1.8e-43 148.9 0.0 3e-42 144.9 0.0 2.1 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CoA_binding_2 PF13380.1 EIW83520.1 - 1.8e-11 44.2 0.0 2.3e-11 43.8 0.0 1.2 1 0 0 1 1 1 1 CoA binding domain Methyltransf_11 PF08241.7 EIW83522.1 - 2e-09 37.8 0.0 3.2e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW83522.1 - 4.4e-09 36.2 0.0 6.1e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW83522.1 - 2.2e-07 30.6 0.0 1.2e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW83522.1 - 3.5e-05 23.0 0.0 0.00026 20.1 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EIW83522.1 - 0.00021 21.6 0.0 0.00053 20.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW83522.1 - 0.0011 19.4 0.0 0.0026 18.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EIW83522.1 - 0.0012 18.9 0.0 0.0023 17.9 0.0 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 EIW83522.1 - 0.0023 18.4 0.0 0.019 15.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EIW83522.1 - 0.016 14.8 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase TPMT PF05724.6 EIW83522.1 - 0.032 13.6 0.0 0.058 12.8 0.0 1.4 1 1 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_26 PF13659.1 EIW83522.1 - 0.036 14.1 0.0 0.096 12.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Asp PF00026.18 EIW83523.1 - 2.2e-62 211.1 13.5 2.7e-62 210.8 9.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW83523.1 - 7e-09 35.8 8.1 9.1e-08 32.2 5.1 2.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal CD20 PF04103.10 EIW83523.1 - 1.5 8.7 9.8 0.28 11.1 1.4 2.8 2 0 0 2 2 2 0 CD20-like family Fungal_trans PF04082.13 EIW83525.1 - 2.7e-13 49.4 0.1 3.8e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW83525.1 - 2.6e-06 27.2 17.7 2.6e-06 27.2 12.3 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain S-methyl_trans PF02574.11 EIW83527.1 - 3.9e-27 95.3 0.1 2.6e-15 56.5 0.0 2.7 2 1 0 2 2 2 2 Homocysteine S-methyltransferase Methyltransf_23 PF13489.1 EIW83529.1 - 1.6e-07 31.1 0.0 2.6e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW83529.1 - 5.4e-06 26.8 0.0 1.1e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW83529.1 - 0.0023 17.5 0.0 0.0082 15.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW83529.1 - 0.0039 17.5 0.0 0.011 16.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 EIW83529.1 - 0.024 14.6 0.1 0.22 11.5 0.0 2.1 1 1 0 2 2 2 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EIW83529.1 - 0.039 13.0 0.0 0.36 9.8 0.0 2.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF1128 PF06569.6 EIW83529.1 - 0.087 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) Methyltransf_8 PF05148.10 EIW83529.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase Glyco_hydro_18 PF00704.23 EIW83531.1 - 2e-58 198.5 1.3 2.9e-58 197.9 0.9 1.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.8 EIW83531.1 - 0.049 12.7 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 TRAM_LAG1_CLN8 PF03798.11 EIW83532.1 - 0.018 14.6 0.2 0.018 14.6 0.2 1.8 2 0 0 2 2 2 0 TLC domain Abhydrolase_6 PF12697.2 EIW83533.1 - 2.1e-28 99.7 1.5 2.8e-28 99.3 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW83533.1 - 1.2e-15 57.5 0.1 1.9e-15 56.9 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIW83533.1 - 6.8e-09 35.4 0.0 3.1e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_1 PF00561.15 EIW83533.1 - 3.5e-07 30.0 0.1 5.1e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EIW83533.1 - 5.6e-07 30.0 0.0 1.6e-06 28.5 0.0 1.7 2 0 0 2 2 2 1 Thioesterase domain Chlorophyllase2 PF12740.2 EIW83533.1 - 5.7e-05 22.1 0.2 0.00029 19.8 0.2 2.0 1 1 0 1 1 1 1 Chlorophyllase enzyme DUF3089 PF11288.3 EIW83533.1 - 0.00095 18.3 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) DUF676 PF05057.9 EIW83533.1 - 0.0013 18.0 0.0 0.005 16.1 0.0 1.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) DUF900 PF05990.7 EIW83533.1 - 0.0023 17.3 0.0 0.0033 16.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 EIW83533.1 - 0.0038 16.8 0.1 0.0055 16.3 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.10 EIW83533.1 - 0.011 14.6 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase Chlorophyllase PF07224.6 EIW83533.1 - 0.013 14.3 0.2 0.026 13.3 0.1 1.5 1 1 0 1 1 1 0 Chlorophyllase DUF726 PF05277.7 EIW83533.1 - 0.023 13.6 0.0 0.032 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) DUF2424 PF10340.4 EIW83533.1 - 0.023 13.3 0.0 0.032 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 EIW83533.1 - 0.025 14.1 0.1 0.036 13.6 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 EIW83533.1 - 0.032 13.8 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Esterase PF00756.15 EIW83533.1 - 0.065 12.6 0.0 0.1 11.9 0.0 1.3 1 1 0 1 1 1 0 Putative esterase Abhydro_lipase PF04083.11 EIW83533.1 - 0.11 11.8 0.0 4.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region SR-25 PF10500.4 EIW83534.1 - 0.017 14.6 17.4 0.039 13.4 12.0 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Nucleo_P87 PF07267.6 EIW83534.1 - 8 5.0 6.1 11 4.5 4.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PB1 PF00564.19 EIW83536.1 - 6.4e-12 44.9 0.0 1.2e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 PB1 domain TPR_11 PF13414.1 EIW83536.1 - 3.7e-07 29.7 2.2 2.6e-05 23.7 0.0 3.7 3 1 1 4 4 4 1 TPR repeat TPR_1 PF00515.23 EIW83536.1 - 1.4e-05 24.4 1.3 0.39 10.4 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIW83536.1 - 1.6e-05 24.4 1.9 3.5 7.7 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIW83536.1 - 0.00099 19.7 3.9 1.6 9.4 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIW83536.1 - 0.0018 17.9 0.7 1.3 8.9 0.0 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIW83536.1 - 0.048 13.5 2.7 1.4 8.9 0.1 3.1 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIW83536.1 - 0.055 13.2 0.9 4.4 7.3 0.0 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIW83536.1 - 0.14 12.8 4.2 26 5.8 0.0 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF1363 PF07101.6 EIW83538.1 - 0.11 12.5 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1363) SWIRM PF04433.12 EIW83540.1 - 1.6e-15 57.0 0.0 3.1e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EIW83540.1 - 1.7e-09 37.5 0.0 3.4e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIW83540.1 - 0.0061 16.6 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EIW83540.1 - 0.64 9.5 6.8 1.3 8.6 4.7 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type TPR_19 PF14559.1 EIW83541.1 - 9.4e-26 89.9 34.0 2.4e-08 34.2 1.2 9.7 8 2 2 10 10 9 5 Tetratricopeptide repeat TPR_2 PF07719.12 EIW83541.1 - 1.2e-23 81.0 42.9 7.5e-05 22.3 0.3 14.5 15 0 0 15 15 14 6 Tetratricopeptide repeat TPR_11 PF13414.1 EIW83541.1 - 3e-22 78.0 45.5 1.4e-05 24.6 0.0 11.5 8 4 6 14 14 14 10 TPR repeat TPR_16 PF13432.1 EIW83541.1 - 1.1e-20 73.7 13.2 2.1e-08 34.6 0.9 11.8 9 4 4 13 13 13 6 Tetratricopeptide repeat TPR_1 PF00515.23 EIW83541.1 - 2.3e-19 68.1 22.9 0.00017 21.0 0.0 11.1 12 0 0 12 12 11 3 Tetratricopeptide repeat TPR_12 PF13424.1 EIW83541.1 - 4.8e-19 68.0 39.2 9.9e-07 28.6 1.2 9.1 8 2 3 11 11 11 8 Tetratricopeptide repeat Apc3 PF12895.2 EIW83541.1 - 2.5e-15 56.3 14.8 0.0019 18.3 2.6 6.2 4 2 3 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EIW83541.1 - 6.4e-15 54.3 61.7 4.9e-07 29.8 0.3 15.5 13 4 5 18 18 16 6 Tetratricopeptide repeat TPR_8 PF13181.1 EIW83541.1 - 4.9e-13 47.8 8.9 0.00099 18.7 0.1 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 EIW83541.1 - 2.1e-05 23.9 21.0 0.0084 15.8 0.2 8.9 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 EIW83541.1 - 2.1e-05 24.6 0.4 5.5e-05 23.3 0.2 10.3 15 0 0 15 15 12 3 Tetratricopeptide repeat TPR_10 PF13374.1 EIW83541.1 - 0.00034 20.4 38.6 0.05 13.5 0.1 9.8 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIW83541.1 - 0.0017 18.4 20.0 2.8 8.3 0.1 9.1 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_4 PF07721.9 EIW83541.1 - 0.015 15.6 26.3 2.3 8.8 0.0 9.4 10 0 0 10 10 9 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIW83541.1 - 0.23 11.3 12.0 14 5.6 0.3 5.6 4 1 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat His_Phos_1 PF00300.17 EIW83542.1 - 3.3e-26 92.2 0.0 4e-26 92.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) zf-HIT PF04438.11 EIW83543.1 - 1e-08 34.6 11.9 1.4e-08 34.2 8.3 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 EIW83543.1 - 0.0072 16.1 10.8 0.011 15.5 7.5 1.2 1 0 0 1 1 1 1 MYND finger zf-B_box PF00643.19 EIW83543.1 - 0.016 15.0 6.3 0.023 14.5 4.4 1.2 1 0 0 1 1 1 0 B-box zinc finger zf-C3HC4_2 PF13923.1 EIW83543.1 - 0.35 10.9 6.6 0.54 10.3 4.6 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RNase_T PF00929.19 EIW83544.1 - 1.1e-17 64.8 0.0 1.7e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 Exonuclease FA_desaturase_2 PF03405.9 EIW83544.1 - 0.058 12.1 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 Fatty acid desaturase PPPI_inhib PF14895.1 EIW83544.1 - 0.06 12.0 0.0 0.093 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein phosphatase 1 inhibitor F-box-like PF12937.2 EIW83545.1 - 0.00091 18.9 0.2 0.0019 17.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW83545.1 - 0.0036 16.9 0.3 0.0092 15.6 0.2 1.6 1 0 0 1 1 1 1 F-box domain Herpes_UL52 PF03121.10 EIW83545.1 - 0.0049 16.5 1.2 0.011 15.5 0.8 1.5 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase Prim_Zn_Ribbon PF08273.7 EIW83546.1 - 0.11 12.6 1.3 6.3 6.9 0.1 2.4 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Glyco_hydro_18 PF00704.23 EIW83547.1 - 2.3e-63 214.7 9.6 4.4e-63 213.7 6.7 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 DUF187 PF02638.10 EIW83547.1 - 0.011 14.6 0.0 0.021 13.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 F-box PF00646.28 EIW83548.1 - 0.046 13.3 3.2 4.7 6.9 0.2 2.8 3 1 0 3 3 3 0 F-box domain Cys_Met_Meta_PP PF01053.15 EIW83549.1 - 8.1e-55 185.6 0.0 1.9e-54 184.4 0.0 1.6 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme MAPEG PF01124.13 EIW83550.1 - 8.3e-24 83.6 2.6 1.1e-23 83.2 1.8 1.1 1 0 0 1 1 1 1 MAPEG family PC-Esterase PF13839.1 EIW83551.1 - 9.2e-08 32.2 0.0 2.6e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p R3H PF01424.17 EIW83552.1 - 6.6e-12 44.9 0.0 1.8e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 R3H domain G-patch_2 PF12656.2 EIW83552.1 - 0.00033 20.4 0.7 0.00033 20.4 0.5 2.5 2 0 0 2 2 2 1 DExH-box splicing factor binding site HSP70 PF00012.15 EIW83554.1 - 6.8e-161 536.1 0.0 1.2e-160 535.3 0.0 1.4 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIW83554.1 - 6.7e-12 44.6 0.1 4.2e-11 42.0 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein Pkinase PF00069.20 EIW83555.1 - 4.1e-45 153.9 0.0 5e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW83555.1 - 1.3e-35 122.7 0.0 1.6e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW83555.1 - 0.0027 17.5 0.0 0.015 15.0 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIW83555.1 - 0.0066 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Fructosamin_kin PF03881.9 EIW83555.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Fructosamine kinase Toxin_57 PF15535.1 EIW83556.1 - 0.023 14.7 0.0 0.056 13.4 0.0 1.7 1 0 0 1 1 1 0 Putative toxin 57 Methyltransf_22 PF13383.1 EIW83557.1 - 1.5e-27 96.6 0.0 1.9e-27 96.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 EIW83557.1 - 4.2e-09 36.5 0.0 6.5e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain DUF1892 PF08987.5 EIW83557.1 - 0.079 12.9 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1892) Glyoxal_oxid_N PF07250.6 EIW83558.1 - 3.7e-38 130.9 0.0 3e-35 121.4 0.0 3.7 3 1 0 3 3 3 2 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EIW83558.1 - 2.9e-20 72.1 0.1 6.2e-20 71.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_4 PF13418.1 EIW83558.1 - 0.03 14.0 17.6 0.2 11.4 0.0 6.1 6 1 0 6 6 6 0 Galactose oxidase, central domain Aldo_ket_red PF00248.16 EIW83559.1 - 2.1e-48 164.5 0.0 2.5e-48 164.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SAM_PNT PF02198.11 EIW83560.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain COesterase PF00135.23 EIW83561.1 - 7.2e-86 289.0 0.5 9.2e-86 288.6 0.4 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW83561.1 - 1.7e-09 37.5 2.0 9.6e-09 35.1 1.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW83561.1 - 0.0018 18.0 0.2 0.0031 17.2 0.2 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIW83561.1 - 0.0056 15.9 0.2 0.015 14.5 0.2 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Maf PF02545.9 EIW83562.1 - 1.2e-39 135.5 0.0 1.2e-38 132.1 0.0 1.9 1 1 0 1 1 1 1 Maf-like protein ADH_zinc_N PF00107.21 EIW83562.1 - 0.057 12.9 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TPR_6 PF13174.1 EIW83562.1 - 0.14 12.7 0.0 0.36 11.3 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat COPIIcoated_ERV PF07970.7 EIW83563.1 - 1.3e-35 123.0 0.8 1.9e-35 122.5 0.5 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EIW83563.1 - 1.3e-19 69.9 0.1 3.8e-19 68.4 0.0 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF2776 PF10951.3 EIW83564.1 - 0.018 14.1 0.0 0.037 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2776) Arm PF00514.18 EIW83564.1 - 0.1 12.4 0.2 6.6 6.7 0.1 3.1 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat CBM_5_12 PF02839.9 EIW83565.1 - 0.00015 21.2 6.5 0.00015 21.2 4.5 2.1 2 0 0 2 2 2 1 Carbohydrate binding domain Glyoxalase PF00903.20 EIW83566.1 - 4.9e-24 84.7 0.1 6.2e-24 84.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EIW83566.1 - 7.1e-17 61.9 0.0 9.4e-17 61.5 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EIW83566.1 - 2.8e-09 36.9 0.0 6e-09 35.8 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EIW83566.1 - 0.0016 18.3 0.0 0.005 16.7 0.0 1.8 1 1 0 1 1 1 1 Glyoxalase-like domain p450 PF00067.17 EIW83567.1 - 8.9e-77 258.5 0.1 1.4e-76 257.9 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 zf-C3HC4_3 PF13920.1 EIW83569.1 - 1.1e-11 44.1 3.7 1.7e-11 43.6 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW83569.1 - 1.1e-09 38.1 1.7 2e-09 37.2 1.2 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW83569.1 - 7.6e-09 35.1 4.5 1.3e-08 34.4 3.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIW83569.1 - 9.3e-09 34.8 0.9 1.9e-08 33.8 0.7 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW83569.1 - 8e-08 31.9 5.7 1.3e-07 31.3 3.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EIW83569.1 - 0.0063 16.2 0.9 0.0063 16.2 0.6 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EIW83569.1 - 0.0098 15.7 8.2 0.16 11.8 6.0 2.4 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING DUF1644 PF07800.7 EIW83569.1 - 0.024 14.4 5.0 1.5 8.6 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1644) Rad50_zn_hook PF04423.9 EIW83569.1 - 0.088 12.2 0.6 2.5 7.6 0.0 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-CHY PF05495.7 EIW83569.1 - 0.096 12.8 1.2 0.15 12.2 0.8 1.3 1 0 0 1 1 1 0 CHY zinc finger zf-RING_4 PF14570.1 EIW83569.1 - 0.13 11.8 6.1 0.65 9.6 4.4 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain UPF0547 PF10571.4 EIW83569.1 - 1.5 8.5 7.9 0.9 9.2 0.7 2.9 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-MIZ PF02891.15 EIW83569.1 - 4.6 6.8 9.5 1.1e+02 2.4 0.3 2.9 1 1 1 2 2 2 0 MIZ/SP-RING zinc finger Glyco_hydro_32N PF00251.15 EIW83570.1 - 9.8e-76 255.0 4.7 9.5e-63 212.3 1.2 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EIW83570.1 - 1.1e-11 44.8 0.0 2.6e-11 43.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal BNR PF02012.15 EIW83570.1 - 0.031 14.0 1.6 0.25 11.3 0.4 3.4 2 0 0 2 2 2 0 BNR/Asp-box repeat Glyco_hydro_28 PF00295.12 EIW83573.1 - 1.5e-37 129.3 6.1 2.3e-37 128.7 4.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Rhodanese PF00581.15 EIW83574.1 - 1.1e-19 70.8 0.0 3.4e-12 46.6 0.0 2.8 2 1 0 2 2 2 2 Rhodanese-like domain Hexokinase_2 PF03727.11 EIW83575.1 - 1.2e-60 204.7 0.7 1.3e-38 132.5 0.0 3.2 2 1 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EIW83575.1 - 2.6e-56 190.2 0.0 6.6e-56 188.9 0.0 1.6 1 1 0 1 1 1 1 Hexokinase HAD_2 PF13419.1 EIW83576.1 - 5.8e-11 42.9 0.0 9.1e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIW83576.1 - 4.2e-07 29.5 0.0 8e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EIW83576.1 - 2.2e-06 28.2 0.1 0.064 13.6 0.0 2.2 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIW83576.1 - 0.087 12.9 0.2 0.17 12.0 0.1 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Aldose_epim PF01263.15 EIW83577.1 - 1.3e-32 113.0 0.0 1.6e-32 112.8 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Glyco_transf_8 PF01501.15 EIW83578.1 - 1.3e-25 90.1 0.0 2e-25 89.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 MFS_1 PF07690.11 EIW83579.1 - 1.8e-44 151.8 45.5 1.9e-42 145.2 28.2 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Fumarate_red_D PF02313.12 EIW83579.1 - 0.017 15.0 0.9 0.35 10.7 0.2 2.8 2 0 0 2 2 2 0 Fumarate reductase subunit D GST_N_3 PF13417.1 EIW83580.1 - 4.3e-12 46.0 0.0 9.8e-12 44.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW83580.1 - 4.5e-11 42.5 0.0 9.9e-11 41.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW83580.1 - 2.9e-10 40.1 0.0 5.8e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW83580.1 - 1.1e-06 28.4 0.0 2.1e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIW83580.1 - 0.00048 19.9 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain p450 PF00067.17 EIW83582.1 - 2.2e-41 141.8 0.0 2.9e-41 141.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-RING_5 PF14634.1 EIW83585.1 - 0.055 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 zinc-RING finger domain MFS_1 PF07690.11 EIW83589.1 - 1e-45 156.0 81.1 4.3e-41 140.8 35.4 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW83589.1 - 1.3e-09 37.2 8.3 1.3e-09 37.2 5.8 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter IncA PF04156.9 EIW83590.1 - 3.4 7.2 6.8 4.4 6.8 4.7 1.2 1 0 0 1 1 1 0 IncA protein Adeno_E3B PF03376.9 EIW83591.1 - 0.73 9.7 7.1 1.1 9.2 1.3 2.8 2 0 0 2 2 2 0 Adenovirus E3B protein DUF4044 PF13253.1 EIW83591.1 - 0.97 8.6 6.4 0.86 8.8 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) MgtE PF01769.11 EIW83591.1 - 1.7 8.9 10.6 22 5.3 0.5 3.0 1 1 2 3 3 3 0 Divalent cation transporter TMEM192 PF14802.1 EIW83592.1 - 0.37 9.6 4.0 0.17 10.6 0.1 2.1 2 0 0 2 2 2 0 TMEM192 family DUF410 PF04190.8 EIW83593.1 - 9e-34 117.1 0.0 1.1e-33 116.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) HSBP1 PF06825.7 EIW83594.1 - 2.3e-15 55.9 3.9 3.1e-15 55.4 2.7 1.2 1 0 0 1 1 1 1 Heat shock factor binding protein 1 DUF111 PF01969.12 EIW83594.1 - 0.013 14.3 0.1 0.016 14.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF111 GOLGA2L5 PF15070.1 EIW83594.1 - 0.018 13.5 0.0 0.019 13.5 0.0 1.0 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 RRN3 PF05327.6 EIW83594.1 - 0.026 12.6 0.0 0.029 12.5 0.0 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF1515 PF07439.6 EIW83594.1 - 0.028 14.2 0.1 0.035 13.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) Matrilin_ccoil PF10393.4 EIW83594.1 - 0.041 13.2 0.7 0.62 9.4 0.5 2.1 1 1 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin RE_LlaJI PF09563.5 EIW83594.1 - 0.048 12.3 0.1 0.059 12.0 0.0 1.1 1 0 0 1 1 1 0 LlaJI restriction endonuclease Baculo_PEP_C PF04513.7 EIW83594.1 - 0.065 13.0 0.1 0.083 12.7 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF935 PF06074.7 EIW83594.1 - 0.065 11.9 0.2 0.074 11.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF935) Terpene_synth_C PF03936.11 EIW83595.1 - 4.7e-15 55.5 0.0 6.3e-14 51.8 0.0 2.0 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Ank_5 PF13857.1 EIW83596.1 - 1.3e-13 50.7 0.0 1.2e-06 28.5 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EIW83596.1 - 1.8e-13 49.5 1.7 1.7e-06 27.5 0.1 4.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.2 EIW83596.1 - 2.1e-13 50.3 0.0 7.4e-09 35.8 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIW83596.1 - 1.5e-10 41.3 0.0 0.011 16.1 0.0 3.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIW83596.1 - 2.9e-09 36.2 0.0 1.9e-05 24.4 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat ECH PF00378.15 EIW83598.1 - 1.3e-52 178.4 0.0 1.6e-52 178.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family zf-U11-48K PF05253.7 EIW83599.1 - 0.14 11.9 0.1 0.32 10.7 0.1 1.7 1 0 0 1 1 1 0 U11-48K-like CHHC zinc finger ECH PF00378.15 EIW83601.1 - 4.6e-47 160.1 0.0 5.7e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Abhydrolase_6 PF12697.2 EIW83602.1 - 2.9e-28 99.3 0.0 3.4e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW83602.1 - 9.2e-16 58.0 0.0 1.6e-15 57.3 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW83602.1 - 1.6e-15 57.1 0.0 2.1e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EIW83602.1 - 1.4e-09 37.8 0.0 2.1e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 EIW83602.1 - 3.3e-09 37.2 0.0 4.1e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.9 EIW83602.1 - 9.3e-06 25.0 0.0 1.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.3 EIW83602.1 - 6.7e-05 22.6 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DUF2048 PF09752.4 EIW83602.1 - 8.4e-05 21.5 0.0 0.19 10.5 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2048) Chlorophyllase PF07224.6 EIW83602.1 - 0.0006 18.6 0.0 0.00092 18.0 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Chlorophyllase2 PF12740.2 EIW83602.1 - 0.0029 16.5 0.0 0.0046 15.8 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.8 EIW83602.1 - 0.013 15.0 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DLH PF01738.13 EIW83602.1 - 0.023 14.0 0.0 0.7 9.1 0.0 2.4 2 0 0 2 2 2 0 Dienelactone hydrolase family Lipase_3 PF01764.20 EIW83602.1 - 0.024 14.2 0.0 0.035 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.3 EIW83602.1 - 0.024 14.0 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_2 PF01674.13 EIW83602.1 - 0.038 13.3 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 2) Integrase_AP2 PF14657.1 EIW83602.1 - 0.098 12.4 0.1 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 AP2-like DNA-binding integrase domain Esterase PF00756.15 EIW83602.1 - 0.13 11.6 0.1 0.27 10.5 0.1 1.5 1 0 0 1 1 1 0 Putative esterase Steroid_dh PF02544.11 EIW83603.1 - 4.1e-32 111.0 3.0 7.1e-32 110.2 2.1 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase YukD PF08817.5 EIW83603.1 - 0.16 12.5 0.0 0.26 11.8 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD PEMT PF04191.8 EIW83603.1 - 0.22 11.6 7.0 0.11 12.6 1.2 2.7 1 1 2 3 3 3 0 Phospholipid methyltransferase Hydrophobin PF01185.13 EIW83604.1 - 8.2e-10 39.0 10.5 9.2e-10 38.8 7.3 1.0 1 0 0 1 1 1 1 Fungal hydrophobin Trefoil PF00088.13 EIW83604.1 - 1.2 8.8 6.0 0.22 11.1 0.7 2.0 2 0 0 2 2 2 0 Trefoil (P-type) domain AMP-binding PF00501.23 EIW83606.1 - 1e-72 244.8 0.0 1.2e-72 244.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIW83606.1 - 7.3e-13 49.2 0.4 2.1e-12 47.7 0.3 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MFS_1 PF07690.11 EIW83607.1 - 3.7e-38 131.1 36.7 3.7e-38 131.1 25.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YMF19 PF02326.10 EIW83607.1 - 0.64 10.6 0.1 0.64 10.6 0.0 2.8 3 0 0 3 3 3 0 Plant ATP synthase F0 DUF202 PF02656.10 EIW83607.1 - 3.7 7.8 15.2 0.12 12.6 1.5 4.1 3 2 2 5 5 5 0 Domain of unknown function (DUF202) DUF914 PF06027.7 EIW83608.1 - 2.1e-92 309.5 5.6 2.4e-92 309.3 3.9 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) DUF2798 PF11391.3 EIW83608.1 - 0.67 9.7 7.8 1.2 8.9 0.8 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2798) Ycf66_N PF07444.6 EIW83608.1 - 0.69 9.6 3.2 1 9.1 0.5 2.5 2 0 0 2 2 2 0 Ycf66 protein N-terminus COesterase PF00135.23 EIW83609.1 - 1.5e-93 314.3 0.0 1.7e-93 314.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW83609.1 - 3.7e-08 33.1 3.2 7.1e-07 29.0 2.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW83609.1 - 0.012 15.4 0.3 0.02 14.6 0.2 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIW83609.1 - 0.035 13.3 0.2 0.062 12.5 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_like2 PF13246.1 EIW83610.1 - 0.074 13.0 0.0 0.39 10.7 0.0 2.2 2 0 0 2 2 2 0 Putative hydrolase of sodium-potassium ATPase alpha subunit COesterase PF00135.23 EIW83611.1 - 6.2e-89 299.1 0.3 7.9e-89 298.7 0.2 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW83611.1 - 1.8e-05 24.4 3.5 0.004 16.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW83611.1 - 0.021 14.5 0.2 0.039 13.6 0.2 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Epimerase PF01370.16 EIW83613.1 - 4.5e-09 36.0 0.0 0.0016 17.9 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIW83613.1 - 9.3e-06 25.0 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIW83613.1 - 4e-05 23.6 0.0 0.0001 22.3 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIW83613.1 - 0.0021 16.7 0.0 0.0042 15.8 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EIW83613.1 - 0.076 13.3 0.0 0.21 11.8 0.0 1.7 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Caudo_TAP PF02413.12 EIW83615.1 - 0.25 11.5 2.5 2.1 8.5 1.6 2.4 2 1 1 3 3 3 0 Caudovirales tail fibre assembly protein Epimerase PF01370.16 EIW83617.1 - 2.7e-06 26.9 0.1 4e-05 23.1 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIW83617.1 - 1.3e-05 24.5 0.0 2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIW83617.1 - 6.3e-05 23.0 0.1 0.00024 21.1 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIW83617.1 - 0.00022 20.0 0.0 0.00038 19.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EIW83617.1 - 0.12 12.7 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain zf-H2C2_2 PF13465.1 EIW83618.1 - 3.9e-07 30.0 0.7 3.9e-07 30.0 0.5 3.9 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIW83618.1 - 6.6e-06 26.0 12.8 0.00021 21.4 2.4 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIW83618.1 - 2.6e-05 24.2 13.2 0.00051 20.2 2.0 3.7 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-met PF12874.2 EIW83618.1 - 0.0012 19.0 0.4 0.0012 19.0 0.3 1.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type Zn_clus PF00172.13 EIW83618.1 - 0.01 15.7 12.9 0.022 14.6 9.0 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-Di19 PF05605.7 EIW83618.1 - 0.017 15.2 5.1 0.85 9.7 0.4 2.6 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EIW83618.1 - 0.16 12.1 2.3 1.4 9.1 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EIW83618.1 - 0.38 10.8 8.7 0.89 9.7 0.3 2.5 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Uricase PF01014.13 EIW83619.1 - 3.7e-64 214.9 0.0 7.1e-38 129.7 0.2 2.4 2 1 0 2 2 2 2 Uricase ATP-synt_G PF04718.10 EIW83620.1 - 6.1e-20 71.7 1.1 3e-19 69.5 0.1 2.1 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit ATP-synt_B PF00430.13 EIW83620.1 - 0.017 14.9 0.9 0.025 14.3 0.6 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) Pho88 PF10032.4 EIW83621.1 - 3.5e-73 244.9 0.0 3.9e-73 244.7 0.0 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) PH PF00169.24 EIW83622.1 - 5.4e-05 23.3 0.0 0.0001 22.4 0.0 1.5 1 0 0 1 1 1 1 PH domain Carbpep_Y_N PF05388.6 EIW83622.1 - 1.5 9.0 5.3 2.9 8.0 1.1 2.4 1 1 1 2 2 2 0 Carboxypeptidase Y pro-peptide SDA1 PF05285.7 EIW83622.1 - 1.7 7.8 9.3 3 7.0 6.5 1.4 1 0 0 1 1 1 0 SDA1 NmrA PF05368.8 EIW83623.1 - 0.00057 19.2 0.0 0.026 13.7 0.0 2.2 2 0 0 2 2 2 2 NmrA-like family Epimerase PF01370.16 EIW83623.1 - 0.00088 18.7 0.6 1.1 8.6 0.0 2.9 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EIW83623.1 - 0.0059 16.8 0.1 0.017 15.4 0.1 1.9 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain RRF PF01765.14 EIW83624.1 - 0.022 14.2 4.6 0.042 13.3 3.2 1.3 1 0 0 1 1 1 0 Ribosome recycling factor DUF4230 PF14014.1 EIW83624.1 - 5.6 6.8 6.9 0.3 10.9 0.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4230) Epimerase PF01370.16 EIW83625.1 - 0.00093 18.6 0.0 0.0029 17.0 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIW83626.1 - 1.6e-07 30.8 0.0 2.6e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EIW83626.1 - 3.3e-07 30.0 0.0 7.3e-05 22.3 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW83626.1 - 0.0015 18.5 0.0 0.0056 16.6 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIW83626.1 - 0.079 11.6 0.0 0.39 9.3 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EIW83626.1 - 0.099 11.5 0.0 0.36 9.7 0.0 2.1 1 1 0 1 1 1 0 Male sterility protein Semialdhyde_dh PF01118.19 EIW83626.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 EIW83626.1 - 0.12 12.9 0.0 0.24 11.9 0.0 1.5 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase COesterase PF00135.23 EIW83627.1 - 4.7e-34 117.9 0.2 7.4e-34 117.3 0.1 1.2 1 0 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EIW83627.1 - 0.0098 15.1 0.0 0.02 14.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Arv1 PF04161.8 EIW83628.1 - 7.5e-25 88.0 0.0 1.2e-24 87.4 0.0 1.3 1 0 0 1 1 1 1 Arv1-like family DUF829 PF05705.9 EIW83629.1 - 1.7e-41 142.5 0.0 2.1e-41 142.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 EIW83629.1 - 0.0017 18.2 0.1 0.0029 17.5 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIW83629.1 - 0.0026 17.0 0.0 0.0046 16.1 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family BAAT_C PF08840.6 EIW83629.1 - 0.14 11.8 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Pheromone PF08015.6 EIW83630.1 - 0.36 11.6 5.9 1.3 9.8 4.0 2.4 1 1 0 1 1 1 0 Fungal mating-type pheromone DUF3863 PF12979.2 EIW83631.1 - 0.12 10.9 0.6 0.18 10.3 0.1 1.5 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3863) DUF3104 PF11302.3 EIW83631.1 - 0.14 11.5 0.1 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) MoaF PF10703.4 EIW83633.1 - 0.15 11.1 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Molybdenum cofactor biosynthesis protein F Mito_carr PF00153.22 EIW83634.1 - 2.1e-64 213.2 7.7 1.3e-22 79.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein COesterase PF00135.23 EIW83635.1 - 2.9e-94 316.7 0.3 3.6e-94 316.3 0.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW83635.1 - 2.7e-07 30.3 2.0 5.2e-06 26.1 1.4 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW83635.1 - 0.033 13.9 0.3 0.071 12.8 0.2 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EIW83635.1 - 0.13 11.4 0.8 0.27 10.4 0.2 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family UPF0086 PF01868.11 EIW83637.1 - 1.1e-19 69.8 0.0 2e-19 68.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Fork_head PF00250.13 EIW83640.1 - 0.09 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Fork head domain Isochorismatase PF00857.15 EIW83641.1 - 2.8e-23 82.7 0.0 3.6e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family Thioredoxin PF00085.15 EIW83642.1 - 3.8e-18 65.0 0.0 9.9e-18 63.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.19 EIW83642.1 - 1.1e-17 63.6 0.0 1.2e-16 60.3 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_8 PF13905.1 EIW83642.1 - 5.4e-06 26.4 0.1 0.038 14.0 0.0 2.7 1 1 1 2 2 2 2 Thioredoxin-like HyaE PF07449.6 EIW83642.1 - 2.6e-05 24.0 0.0 0.00055 19.8 0.0 2.5 2 1 0 2 2 2 1 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.1 EIW83642.1 - 0.00016 21.8 0.0 0.0016 18.6 0.0 2.3 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EIW83642.1 - 0.0047 16.7 0.1 0.014 15.2 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin domain DIM1 PF02966.11 EIW83642.1 - 0.012 15.0 0.0 0.018 14.5 0.0 1.2 1 0 0 1 1 1 0 Mitosis protein DIM1 GST_N_3 PF13417.1 EIW83642.1 - 0.037 14.2 0.0 0.071 13.3 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain Thioredoxin_4 PF13462.1 EIW83642.1 - 0.041 13.8 0.5 6.3 6.7 0.0 3.2 2 1 1 3 3 3 0 Thioredoxin Thioredoxin_7 PF13899.1 EIW83642.1 - 0.077 13.0 0.1 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 Thioredoxin-like SH3BGR PF04908.10 EIW83642.1 - 0.08 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 SH3-binding, glutamic acid-rich protein DUF35_N PF12172.3 EIW83643.1 - 1.5 8.7 7.5 0.25 11.2 1.9 2.1 2 1 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) DUF1777 PF08648.7 EIW83644.1 - 1.8 8.2 24.2 0.52 10.0 12.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Orn_Arg_deC_N PF02784.11 EIW83645.1 - 6.5e-72 241.7 0.0 1.2e-71 240.8 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EIW83645.1 - 7.2e-31 106.3 0.0 1.2e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain PTPA PF03095.10 EIW83646.1 - 1.3e-86 290.5 0.0 1.5e-86 290.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Ku PF02735.11 EIW83647.1 - 1.2e-29 103.1 0.0 3.4e-29 101.7 0.0 1.7 1 1 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EIW83647.1 - 6.2e-20 71.5 0.0 1.1e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain SAP PF02037.22 EIW83647.1 - 1.4e-09 37.2 0.1 3.7e-09 35.8 0.1 1.8 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.9 EIW83647.1 - 1e-06 29.1 0.1 2.7e-06 27.8 0.1 1.7 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm VWA_2 PF13519.1 EIW83647.1 - 0.054 13.6 0.0 0.19 11.8 0.0 1.9 1 1 0 1 1 1 0 von Willebrand factor type A domain HeH PF12949.2 EIW83647.1 - 0.1 12.1 0.1 0.38 10.3 0.1 2.0 1 1 0 1 1 1 0 HeH/LEM domain SE PF08491.5 EIW83647.1 - 0.22 10.3 0.0 9.3 4.9 0.0 2.1 2 0 0 2 2 2 0 Squalene epoxidase ABC2_membrane_2 PF12679.2 EIW83648.1 - 0.0038 16.1 2.5 0.0038 16.1 1.7 2.3 2 0 0 2 2 2 1 ABC-2 family transporter protein FMO-like PF00743.14 EIW83649.1 - 3.4e-20 71.7 0.0 1.7e-18 66.1 0.0 2.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EIW83649.1 - 4.3e-20 72.6 0.0 3.7e-19 69.5 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW83649.1 - 1.1e-11 44.9 0.0 8.2e-10 38.8 0.0 2.5 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW83649.1 - 2.6e-10 39.7 0.0 1.5e-06 27.3 0.0 2.9 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 EIW83649.1 - 1.2e-08 35.1 0.0 8.4e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 EIW83649.1 - 3.1e-06 27.0 0.2 8.9e-06 25.6 0.0 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EIW83649.1 - 1.2e-05 24.5 0.9 2.1e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.1 EIW83649.1 - 1.3e-05 25.0 0.5 0.052 13.3 0.0 3.3 3 1 0 3 3 3 2 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 EIW83649.1 - 3.6e-05 23.4 0.9 0.0038 16.8 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 EIW83649.1 - 3.9e-05 22.2 0.1 0.00013 20.6 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EIW83649.1 - 6.2e-05 22.2 0.0 0.00013 21.1 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW83649.1 - 0.00015 22.0 2.2 0.0085 16.4 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIW83649.1 - 0.00045 19.1 2.5 0.015 14.1 0.0 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EIW83649.1 - 0.00072 18.5 0.2 0.0017 17.2 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EIW83649.1 - 0.00098 18.1 0.4 0.2 10.5 0.0 3.0 3 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EIW83649.1 - 0.0015 18.7 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EIW83649.1 - 0.0047 15.8 0.3 0.58 9.0 0.0 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein 2-Hacid_dh_C PF02826.14 EIW83649.1 - 0.007 15.5 0.0 0.29 10.2 0.0 2.5 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.12 EIW83649.1 - 0.018 14.1 0.0 0.051 12.6 0.0 1.7 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 EIW83649.1 - 0.062 11.9 0.2 0.42 9.1 0.1 2.2 3 0 0 3 3 3 0 Tryptophan halogenase TrkA_N PF02254.13 EIW83649.1 - 0.14 12.1 0.0 6.1 6.8 0.0 2.5 2 0 0 2 2 2 0 TrkA-N domain Sugar_tr PF00083.19 EIW83650.1 - 6.7e-104 347.9 20.7 7.5e-104 347.7 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW83650.1 - 2.2e-24 85.8 45.8 2.9e-16 59.1 9.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-RVT PF13966.1 EIW83653.1 - 0.0043 17.3 0.1 0.0063 16.7 0.1 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase UPF0086 PF01868.11 EIW83654.1 - 0.03 13.9 0.0 0.093 12.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function UPF0086 p450 PF00067.17 EIW83661.1 - 3.9e-65 220.1 0.0 4.4e-65 219.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.16 EIW83665.1 - 2.4e-67 226.7 0.0 3e-67 226.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RHH_1 PF01402.16 EIW83665.1 - 0.0092 15.8 0.4 0.47 10.4 0.0 2.7 2 0 0 2 2 2 1 Ribbon-helix-helix protein, copG family zf-C2H2 PF00096.21 EIW83666.1 - 5.6e-12 45.2 16.1 0.00019 21.5 0.3 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW83666.1 - 7e-11 41.8 15.2 1.5e-05 25.0 0.1 3.9 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIW83666.1 - 3.1e-10 39.6 14.2 0.0018 18.4 0.1 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIW83666.1 - 0.0036 17.1 1.6 2.6 8.0 0.0 3.1 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EIW83666.1 - 0.046 13.9 8.4 0.42 10.8 0.3 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIW83666.1 - 0.95 9.6 11.6 2.6 8.3 0.2 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-AN1 PF01428.11 EIW83666.1 - 1.8 8.4 9.4 14 5.6 5.3 3.0 1 1 1 2 2 2 0 AN1-like Zinc finger DUF4604 PF15377.1 EIW83668.1 - 1.2e-20 74.3 21.8 3.2e-19 69.6 15.1 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4604) Serglycin PF04360.7 EIW83669.1 - 0.015 15.0 0.8 0.026 14.2 0.6 1.5 1 0 0 1 1 1 0 Serglycin AIG1 PF04548.11 EIW83670.1 - 8.7e-11 41.3 0.0 1.1e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 EIW83670.1 - 2.7e-10 40.2 0.0 4.4e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIW83670.1 - 7.2e-05 22.0 0.0 0.00016 20.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 IIGP PF05049.8 EIW83670.1 - 0.00019 20.3 0.0 0.00032 19.6 0.0 1.3 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) Ras PF00071.17 EIW83670.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW83670.1 - 0.0025 18.2 0.0 0.0041 17.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 EIW83670.1 - 0.0031 16.5 0.0 0.0043 16.0 0.0 1.2 1 0 0 1 1 1 1 Septin FtsK_SpoIIIE PF01580.13 EIW83670.1 - 0.0063 16.0 0.0 0.026 14.0 0.0 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_16 PF13191.1 EIW83670.1 - 0.0072 16.3 0.1 0.017 15.0 0.0 1.8 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 EIW83670.1 - 0.0074 16.5 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Dynamin_N PF00350.18 EIW83670.1 - 0.015 15.1 0.4 0.045 13.5 0.2 1.7 1 1 1 2 2 2 0 Dynamin family AAA_22 PF13401.1 EIW83670.1 - 0.02 15.0 0.1 0.11 12.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EIW83670.1 - 0.026 14.0 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EIW83670.1 - 0.037 14.8 0.5 0.25 12.1 0.4 2.3 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 EIW83670.1 - 0.041 12.8 0.0 0.065 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 EIW83670.1 - 0.071 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_10 PF12846.2 EIW83670.1 - 0.084 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain Flavodoxin_3 PF12641.2 EIW83670.1 - 0.11 11.9 0.0 2.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Flavodoxin domain RNA_helicase PF00910.17 EIW83670.1 - 0.14 12.3 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EIW83670.1 - 0.16 11.5 0.0 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain zf-C2H2 PF00096.21 EIW83676.1 - 1.6e-06 28.0 7.5 0.0015 18.7 0.5 2.5 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW83676.1 - 3.5e-05 23.8 4.6 0.008 16.4 0.4 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIW83676.1 - 0.00017 21.3 0.5 0.00058 19.6 0.3 2.0 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EIW83676.1 - 0.0026 17.8 1.5 0.0044 17.0 0.7 1.6 1 1 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.2 EIW83676.1 - 0.039 14.1 3.7 0.24 11.6 0.0 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIW83676.1 - 0.075 13.2 2.7 2.9 8.1 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 EIW83676.1 - 0.16 11.9 0.1 0.16 11.9 0.1 2.5 3 0 0 3 3 3 0 Zinc ribbon domain Aldo_ket_red PF00248.16 EIW83677.1 - 5e-72 242.0 0.1 6.1e-72 241.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FtsA PF14450.1 EIW83677.1 - 0.007 16.1 0.0 5.6 6.8 0.0 2.4 2 0 0 2 2 2 2 Cell division protein FtsA zf-C2H2 PF00096.21 EIW83678.1 - 3.6e-06 27.0 21.0 0.024 14.9 0.3 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW83678.1 - 0.0062 16.7 18.3 0.18 12.2 0.2 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIW83678.1 - 0.2 12.0 0.3 0.2 12.0 0.2 3.6 3 1 0 3 3 3 0 Zinc-finger double domain Tmemb_55A PF09788.4 EIW83678.1 - 1.5 7.8 6.9 3.5 6.6 4.7 1.6 1 1 0 1 1 1 0 Transmembrane protein 55A GST_N_3 PF13417.1 EIW83679.1 - 1.1e-12 47.9 0.1 2.4e-12 46.8 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW83679.1 - 1.3e-08 34.6 0.0 2.9e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIW83679.1 - 0.00049 20.5 0.0 0.0014 19.0 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIW83679.1 - 0.002 17.9 0.0 0.0061 16.4 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW83679.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Aldo_ket_red PF00248.16 EIW83680.1 - 3.7e-68 229.4 0.1 4.8e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Tubulin PF00091.20 EIW83681.1 - 2.7e-65 220.2 0.0 5.1e-65 219.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIW83681.1 - 2.2e-38 131.1 0.0 3.3e-38 130.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EIW83681.1 - 1e-06 28.8 0.0 3.5e-06 27.0 0.0 1.9 3 0 0 3 3 3 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EIW83681.1 - 0.012 15.0 0.0 0.025 14.0 0.0 1.5 1 0 0 1 1 1 0 Tubulin domain Hus1 PF04005.7 EIW83682.1 - 1.8e-79 266.7 0.3 2e-79 266.6 0.2 1.0 1 0 0 1 1 1 1 Hus1-like protein Transketolase_N PF00456.16 EIW83684.1 - 2e-18 66.3 1.6 2.4e-17 62.7 1.1 2.0 1 1 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transketolase_C PF02780.15 EIW83684.1 - 5.1e-07 29.6 0.0 1.1e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 EIW83684.1 - 2.3e-06 27.2 0.2 5.2e-06 26.0 0.2 1.7 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain TPP_enzyme_C PF02775.16 EIW83684.1 - 5.9e-05 22.6 0.1 0.00022 20.8 0.0 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EIW83684.1 - 0.0039 15.9 0.0 0.008 14.9 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component FtsJ PF01728.14 EIW83685.1 - 2.2e-08 34.2 0.0 3.9e-08 33.4 0.0 1.3 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 EIW83685.1 - 0.00012 22.6 0.0 0.00025 21.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Amidase PF01425.16 EIW83686.1 - 1.1e-107 360.6 0.0 1.3e-107 360.4 0.0 1.0 1 0 0 1 1 1 1 Amidase DDE_1 PF03184.14 EIW83687.1 - 6.3e-38 130.0 0.1 8.9e-38 129.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_Tc5 PF03221.11 EIW83687.1 - 7.1e-07 28.9 0.0 2e-06 27.5 0.0 1.8 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DcpS_C PF11969.3 EIW83688.1 - 1.5e-24 86.4 0.1 2e-24 86.0 0.1 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EIW83688.1 - 1.7e-09 38.1 3.9 8.6e-09 35.8 2.7 1.9 1 1 0 1 1 1 1 HIT domain Amidase PF01425.16 EIW83689.1 - 5.8e-105 351.6 0.0 6.7e-105 351.4 0.0 1.0 1 0 0 1 1 1 1 Amidase RanGAP1_C PF07834.6 EIW83689.1 - 0.059 12.8 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 RanGAP1 C-terminal domain adh_short PF00106.20 EIW83690.1 - 2.7e-24 85.9 0.3 3.8e-24 85.4 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW83690.1 - 3e-13 50.1 0.0 7.1e-13 48.8 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW83690.1 - 3.3e-11 43.1 0.2 6.9e-11 42.1 0.1 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW83690.1 - 2.7e-08 33.5 0.0 3.7e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW83690.1 - 1e-05 25.6 0.1 1.3e-05 25.2 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EIW83690.1 - 0.00035 19.5 0.0 0.00053 18.9 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EIW83690.1 - 0.00089 18.2 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein MFS_1 PF07690.11 EIW83691.1 - 8.3e-39 133.2 46.6 8.5e-34 116.8 17.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW83691.1 - 1.6e-07 30.3 25.6 2e-05 23.3 17.8 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EIW83691.1 - 4.9e-07 28.3 0.8 9.7e-07 27.3 0.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) UCR_Fe-S_N PF10399.4 EIW83691.1 - 0.043 12.9 0.1 5.6 6.2 0.0 2.7 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal MFS_1 PF07690.11 EIW83692.1 - 3.3e-35 121.4 51.3 6.8e-30 103.9 19.9 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIW83692.1 - 0.0001 20.6 5.2 0.00013 20.2 0.6 2.0 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EIW83692.1 - 0.71 7.9 9.3 0.89 7.5 0.8 2.4 2 1 0 2 2 2 0 Transmembrane secretion effector Terpene_synth_C PF03936.11 EIW83693.1 - 2.5e-20 72.8 0.0 3.3e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain HTH_31 PF13560.1 EIW83693.1 - 0.091 12.9 0.0 2.4 8.4 0.0 2.8 3 0 0 3 3 3 0 Helix-turn-helix domain Aldo_ket_red PF00248.16 EIW83694.1 - 1.4e-47 161.8 0.0 1.6e-47 161.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Epimerase PF01370.16 EIW83695.1 - 5.5e-20 71.8 0.0 7.7e-20 71.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW83695.1 - 1.3e-15 57.8 0.1 2.7e-15 56.8 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIW83695.1 - 2.1e-13 49.6 0.0 3.9e-13 48.7 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EIW83695.1 - 1.2e-11 43.9 1.2 7.6e-11 41.4 0.9 1.9 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EIW83695.1 - 3.3e-06 26.5 0.1 4.8e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EIW83695.1 - 7.2e-05 22.7 0.7 0.00043 20.2 0.5 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EIW83695.1 - 0.00018 20.5 0.1 0.00023 20.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EIW83695.1 - 0.012 15.2 1.4 0.14 11.8 1.0 2.4 1 1 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.19 EIW83695.1 - 0.019 15.2 0.2 0.6 10.4 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 EIW83695.1 - 0.055 12.3 0.0 0.35 9.7 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain Steroid_dh PF02544.11 EIW83696.1 - 1.2e-24 86.8 8.1 2.2e-22 79.4 5.6 3.1 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EIW83696.1 - 0.0013 18.1 4.7 0.0056 15.9 3.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Epimerase PF01370.16 EIW83698.1 - 4.6e-18 65.5 0.0 7.5e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIW83698.1 - 1.3e-12 47.0 0.0 1.9e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIW83698.1 - 2.1e-11 44.1 0.3 5.2e-11 42.8 0.2 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIW83698.1 - 4.3e-09 35.6 0.0 7.7e-08 31.5 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EIW83698.1 - 5.9e-06 25.7 0.2 8.4e-06 25.2 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EIW83698.1 - 0.0012 18.7 0.1 0.0031 17.4 0.1 1.8 1 0 0 1 1 1 1 short chain dehydrogenase DUF4322 PF14210.1 EIW83698.1 - 0.092 12.2 0.1 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4322) LRR_6 PF13516.1 EIW83699.1 - 0.0019 18.0 0.1 4.8 7.5 0.0 3.7 2 1 1 3 3 3 2 Leucine Rich repeat LRR_4 PF12799.2 EIW83699.1 - 0.0022 17.5 0.6 0.072 12.7 0.2 3.0 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EIW83699.1 - 0.03 14.4 1.1 22 5.8 0.1 4.5 3 1 1 4 4 4 0 Leucine rich repeat LRR_8 PF13855.1 EIW83699.1 - 0.055 13.2 1.8 0.22 11.3 0.3 2.5 1 1 0 2 2 2 0 Leucine rich repeat Fork_head PF00250.13 EIW83700.1 - 3.3e-08 33.4 0.1 3.8e-08 33.2 0.1 1.0 1 0 0 1 1 1 1 Fork head domain Thg1C PF14413.1 EIW83701.1 - 1.8e-48 163.1 0.0 2.7e-48 162.6 0.0 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 EIW83701.1 - 4e-43 146.2 0.0 5.8e-43 145.7 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase GGDEF PF00990.16 EIW83701.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 GGDEF domain SbmA_BacA PF05992.7 EIW83701.1 - 0.21 10.7 0.7 4.3 6.4 0.1 2.1 2 0 0 2 2 2 0 SbmA/BacA-like family Sec62 PF03839.11 EIW83702.1 - 0.42 9.9 6.4 0.62 9.4 4.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Ebola_NP PF05505.7 EIW83702.1 - 0.66 7.9 11.7 0.89 7.5 8.1 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein YL1 PF05764.8 EIW83702.1 - 1 8.8 21.0 1.5 8.3 14.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein PsiA PF06952.6 EIW83702.1 - 1.3 8.0 11.0 1.8 7.5 7.6 1.1 1 0 0 1 1 1 0 PsiA protein UCH PF00443.24 EIW83703.1 - 1.5e-48 165.2 0.0 4.3e-48 163.7 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW83703.1 - 1.3e-19 70.7 0.0 3.9e-19 69.1 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EIW83703.1 - 2.2e-12 46.8 6.2 2.2e-12 46.8 4.3 2.5 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein Steroid_dh PF02544.11 EIW83704.1 - 3.2e-25 88.6 8.6 5.5e-23 81.3 6.0 3.1 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EIW83704.1 - 0.0013 18.0 5.3 0.006 15.9 3.7 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Tfb2 PF03849.9 EIW83705.1 - 1.9e-124 415.0 0.0 2.3e-124 414.7 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Complex1_LYR PF05347.10 EIW83707.1 - 3.7e-13 49.0 0.0 7.1e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EIW83707.1 - 1.7e-10 40.9 0.0 3.3e-10 40.0 0.0 1.4 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EIW83707.1 - 8.8e-07 29.3 0.1 1.2e-06 28.9 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like PM0188 PF11477.3 EIW83707.1 - 0.057 12.2 0.8 0.066 12.0 0.6 1.1 1 0 0 1 1 1 0 Sialyltransferase PMO188 Cyanate_lyase PF02560.9 EIW83708.1 - 9.5e-34 114.7 0.0 1.6e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain Spore_YtfJ PF09579.5 EIW83709.1 - 0.074 12.9 0.2 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 Sporulation protein YtfJ (Spore_YtfJ) DUF1479 PF07350.7 EIW83710.1 - 2.8e-128 427.9 0.0 3.1e-128 427.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 EIW83710.1 - 2.8e-05 24.2 0.0 0.022 14.8 0.0 2.6 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) Aldo_ket_red PF00248.16 EIW83711.1 - 1e-63 214.8 0.1 1.1e-63 214.6 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Tfb2 PF03849.9 EIW83712.1 - 1.4e-130 435.1 0.0 1.7e-130 434.9 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EIW83712.1 - 0.0013 18.4 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Aldo_ket_red PF00248.16 EIW83713.1 - 1.3e-62 211.2 0.1 1.5e-62 210.9 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Steroid_dh PF02544.11 EIW83714.1 - 1.7e-24 86.2 7.7 1.9e-22 79.6 5.3 3.1 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EIW83714.1 - 0.0013 18.1 4.9 0.0069 15.7 3.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) p450 PF00067.17 EIW83715.1 - 7e-78 262.1 0.0 8e-78 262.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Adeno_PX PF05829.7 EIW83715.1 - 0.0084 15.5 0.1 0.019 14.4 0.1 1.6 1 0 0 1 1 1 1 Adenovirus late L2 mu core protein (Protein X) p450 PF00067.17 EIW83716.1 - 2.3e-74 250.6 0.0 2.8e-74 250.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GST_N PF02798.15 EIW83718.1 - 9.7e-14 51.3 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EIW83718.1 - 3e-13 49.7 0.0 6.1e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW83718.1 - 5.7e-11 42.2 0.0 1.1e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW83718.1 - 2.6e-10 40.1 0.0 6.1e-10 38.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIW83718.1 - 2.6e-08 33.6 0.0 4.9e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW83718.1 - 0.0018 18.6 0.0 0.003 17.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DDE_Tnp_ISAZ013 PF07592.6 EIW83718.1 - 0.06 12.0 0.1 0.086 11.5 0.1 1.2 1 0 0 1 1 1 0 Rhodopirellula transposase DDE domain MetRS-N PF09635.5 EIW83718.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 MetRS-N binding domain SART-1 PF03343.8 EIW83719.1 - 1.2e-125 420.3 42.7 1.2e-125 420.3 29.6 1.4 2 0 0 2 2 2 1 SART-1 family p450 PF00067.17 EIW83720.1 - 2.7e-75 253.6 0.0 3e-75 253.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aldo_ket_red PF00248.16 EIW83722.1 - 7.2e-46 156.2 0.2 1.6e-45 155.1 0.1 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family Aminotran_1_2 PF00155.16 EIW83723.1 - 1.3e-28 100.0 0.0 2.4e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIW83723.1 - 0.00068 18.8 0.0 0.0013 17.9 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase RrnaAD PF00398.15 EIW83723.1 - 0.14 11.1 0.0 15 4.5 0.0 2.3 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase RabGAP-TBC PF00566.13 EIW83725.1 - 3.8e-46 157.2 0.0 5.3e-46 156.7 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain COX6B PF02297.12 EIW83726.1 - 9e-22 76.8 1.8 1.1e-21 76.6 1.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 EIW83726.1 - 0.011 15.7 0.6 0.015 15.3 0.4 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 EIW83726.1 - 1.1 9.2 4.3 22 5.1 2.7 2.7 1 1 1 2 2 2 0 CHCH domain MFS_1 PF07690.11 EIW83728.1 - 1.5e-25 89.7 33.8 9.4e-18 64.0 12.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW83728.1 - 1.7e-18 66.4 16.2 8.6e-18 64.1 11.1 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter zf-RING_5 PF14634.1 EIW83731.1 - 0.00028 20.5 1.4 0.0084 15.8 0.1 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EIW83731.1 - 0.00058 19.4 0.3 0.00058 19.4 0.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW83731.1 - 0.0038 16.8 6.0 0.037 13.7 0.1 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW83731.1 - 0.047 13.7 0.3 0.047 13.7 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EIW83731.1 - 0.06 12.9 6.3 0.082 12.5 0.1 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.1 EIW83731.1 - 0.12 12.1 9.2 0.35 10.7 6.4 1.7 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.1 EIW83731.1 - 0.2 11.5 0.2 0.2 11.5 0.2 2.3 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EIW83732.1 - 6.9e-06 25.9 3.5 2.7e-05 24.0 2.5 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW83732.1 - 1.7e-05 24.3 3.1 1.7e-05 24.3 2.1 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EIW83732.1 - 4.9e-05 23.1 2.3 4.9e-05 23.1 1.6 1.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EIW83732.1 - 0.00013 21.6 1.4 0.00024 20.7 0.5 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 EIW83732.1 - 0.00021 20.9 6.5 0.0015 18.1 4.5 2.3 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIW83732.1 - 0.00052 19.6 6.1 0.0028 17.2 1.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW83732.1 - 0.0079 15.9 6.9 0.02 14.6 4.8 1.8 1 1 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.1 EIW83732.1 - 8.5 6.0 9.3 9.8 5.8 1.8 2.6 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF4218 PF13960.1 EIW83734.1 - 0.0001 21.7 0.4 0.00028 20.3 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Med3 PF11593.3 EIW83734.1 - 7.3 5.7 10.8 13 4.8 7.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF327 PF03885.8 EIW83736.1 - 0.014 15.2 0.1 0.027 14.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF327) HHH_7 PF14635.1 EIW83736.1 - 0.1 12.7 0.2 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif WD40 PF00400.27 EIW83737.1 - 4.4e-13 48.5 5.8 1e-07 31.5 0.0 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW83737.1 - 0.038 13.4 1.2 1 8.7 0.0 2.7 1 1 1 2 2 2 0 PQQ-like domain DUF2937 PF11157.3 EIW83738.1 - 0.58 9.4 3.5 1.8 7.8 2.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) Sad1_UNC PF07738.8 EIW83739.1 - 2e-19 69.7 0.0 1.9e-11 43.8 0.0 2.5 2 0 0 2 2 2 2 Sad1 / UNC-like C-terminal Pkinase PF00069.20 EIW83740.1 - 2.4e-64 217.0 0.0 3.3e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW83740.1 - 2.6e-36 125.0 0.0 3.6e-36 124.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW83740.1 - 1.6e-10 40.4 0.0 5e-10 38.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like FHA PF00498.21 EIW83740.1 - 9.1e-10 38.5 0.3 1.1e-08 35.0 0.2 2.3 1 1 0 1 1 1 1 FHA domain Kdo PF06293.9 EIW83740.1 - 0.0024 16.9 0.1 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EIW83740.1 - 0.011 15.0 0.2 0.019 14.2 0.1 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EIW83740.1 - 0.12 12.0 3.5 0.4 10.3 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family RimM PF01782.13 EIW83741.1 - 0.01 15.7 0.0 0.018 14.9 0.0 1.3 1 0 0 1 1 1 0 RimM N-terminal domain Pkinase PF00069.20 EIW83742.1 - 9.2e-61 205.2 0.0 1.2e-60 204.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW83742.1 - 5.2e-36 124.0 0.0 6.8e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EIW83742.1 - 4.5e-14 52.3 0.1 1.1e-13 51.0 0.1 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EIW83742.1 - 0.00037 19.5 0.0 0.00051 19.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIW83742.1 - 0.0004 19.4 0.0 0.00073 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW83742.1 - 0.00067 19.4 0.1 0.0014 18.3 0.0 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIW83742.1 - 0.034 13.4 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 EIW83743.1 - 1.7e-54 184.7 0.0 2.2e-54 184.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW83743.1 - 3.1e-25 88.7 0.0 4.4e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EIW83743.1 - 6.5e-15 55.0 0.1 1.5e-14 53.8 0.1 1.7 1 0 0 1 1 1 1 FHA domain APH PF01636.18 EIW83743.1 - 0.0014 18.4 0.0 0.0057 16.4 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW83743.1 - 0.0035 16.3 0.0 0.0053 15.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase PF00069.20 EIW83744.1 - 1.1e-62 211.4 0.0 1.8e-62 210.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW83744.1 - 5.5e-38 130.5 0.0 7.4e-38 130.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EIW83744.1 - 1.1e-12 47.9 0.1 1.8e-12 47.1 0.1 1.4 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EIW83744.1 - 9.9e-07 27.9 0.0 1.3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIW83744.1 - 2.6e-05 23.3 0.1 5e-05 22.4 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW83744.1 - 0.00032 20.4 0.0 0.00058 19.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIW83744.1 - 0.0018 17.6 0.0 0.003 16.9 0.0 1.2 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 EIW83744.1 - 0.12 11.6 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Aldo_ket_red PF00248.16 EIW83746.1 - 8.5e-63 211.8 0.1 9.7e-63 211.6 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EIW83747.1 - 2.5e-64 216.8 0.1 2.8e-64 216.6 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.17 EIW83748.1 - 2e-70 237.5 0.0 2.5e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Reticulon PF02453.12 EIW83748.1 - 0.054 13.1 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Reticulon Aldo_ket_red PF00248.16 EIW83749.1 - 9.3e-19 67.3 0.0 1e-12 47.4 0.0 2.1 1 1 1 2 2 2 2 Aldo/keto reductase family DUF4646 PF15496.1 EIW83752.1 - 8.2e-35 119.5 0.0 1.3e-34 118.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4646) Pro-rich PF15240.1 EIW83752.1 - 0.093 12.8 101.0 1.2 9.2 31.6 2.4 2 0 0 2 2 2 0 Proline-rich DUF1816 PF08846.5 EIW83752.1 - 0.14 11.9 0.0 0.29 10.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1816) CDC45 PF02724.9 EIW83752.1 - 0.64 7.9 4.7 0.85 7.5 3.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Fork_head PF00250.13 EIW83753.1 - 1.1e-17 63.8 0.4 1.1e-08 35.0 0.0 3.1 3 0 0 3 3 3 2 Fork head domain Aldo_ket_red PF00248.16 EIW83754.1 - 5.8e-54 182.8 1.9 2.9e-53 180.5 1.3 1.8 1 1 0 1 1 1 1 Aldo/keto reductase family FtsA PF14450.1 EIW83754.1 - 0.1 12.4 0.0 0.42 10.4 0.0 1.9 2 0 0 2 2 2 0 Cell division protein FtsA Ail_Lom PF06316.6 EIW83756.1 - 0.014 14.9 0.0 0.053 13.0 0.0 1.7 1 1 1 2 2 2 0 Enterobacterial Ail/Lom protein zf-C2H2 PF00096.21 EIW83757.1 - 8.6e-06 25.7 21.0 0.0037 17.5 0.3 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW83757.1 - 0.00023 21.2 22.8 0.012 15.8 0.5 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIW83757.1 - 0.29 11.3 0.0 0.29 11.3 0.0 2.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding Peptidase_M48 PF01435.13 EIW83758.1 - 4.5e-14 52.5 0.0 6.7e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_MA_2 PF13485.1 EIW83758.1 - 0.15 12.1 0.0 0.33 11.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily adh_short PF00106.20 EIW83759.1 - 1.8e-29 102.7 0.4 2.5e-29 102.3 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW83759.1 - 1.3e-24 87.3 0.1 1.7e-24 86.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW83759.1 - 3.3e-10 39.9 0.1 4.8e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW83759.1 - 0.02 14.3 0.0 0.035 13.5 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EIW83759.1 - 0.023 14.5 1.2 0.089 12.5 0.3 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HHH_5 PF14520.1 EIW83759.1 - 0.17 12.1 0.4 3.9 7.7 0.1 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain F-box-like PF12937.2 EIW83760.1 - 0.058 13.1 0.0 0.21 11.3 0.0 2.0 1 0 0 1 1 1 0 F-box-like Svf1 PF08622.5 EIW83761.1 - 7.4e-76 255.2 0.0 9e-76 254.9 0.0 1.1 1 0 0 1 1 1 1 Svf1-like SprB PF13573.1 EIW83761.1 - 0.78 9.3 3.5 0.81 9.3 0.4 2.6 2 0 0 2 2 2 0 SprB repeat p450 PF00067.17 EIW83762.1 - 1.6e-52 178.5 0.0 1.8e-52 178.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW83763.1 - 3.3e-73 246.7 0.0 5.1e-73 246.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EIW83764.1 - 5e-07 29.3 0.0 2.3e-06 27.2 0.0 2.2 1 1 0 1 1 1 1 F-box-like Mrr_cat_2 PF13156.1 EIW83764.1 - 0.19 11.6 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 Restriction endonuclease F-box-like PF12937.2 EIW83765.1 - 4e-09 36.0 0.0 1.3e-08 34.3 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW83765.1 - 0.24 11.0 2.1 2.7 7.7 0.0 3.2 3 0 0 3 3 3 0 F-box domain MAM33 PF02330.11 EIW83766.1 - 2.6e-13 50.1 0.1 2.2e-11 43.9 0.1 2.2 2 0 0 2 2 2 2 Mitochondrial glycoprotein Pacs-1 PF10254.4 EIW83766.1 - 0.045 12.3 0.6 0.07 11.7 0.4 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein DUF329 PF03884.9 EIW83766.1 - 0.12 11.9 0.3 0.26 10.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF329) F-box-like PF12937.2 EIW83768.1 - 1.5e-18 66.2 1.8 2e-09 37.0 0.2 3.1 2 0 0 2 2 2 2 F-box-like F-box PF00646.28 EIW83768.1 - 0.0095 15.5 10.6 1.1 9.0 0.0 4.7 5 0 0 5 5 5 2 F-box domain TPR_16 PF13432.1 EIW83769.1 - 3.5e-12 46.6 9.8 4.5e-05 23.9 0.1 4.7 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EIW83769.1 - 6.3e-09 35.3 1.0 0.0011 18.6 0.1 4.1 3 1 0 3 3 3 2 TPR repeat TPR_19 PF14559.1 EIW83769.1 - 6e-08 32.9 4.4 0.031 14.6 0.1 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIW83769.1 - 7e-08 32.4 12.5 0.034 14.7 0.3 5.5 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EIW83769.1 - 1.3e-07 31.4 4.1 0.005 16.7 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EIW83769.1 - 9.2e-05 22.3 0.1 1.9 8.8 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.12 EIW83769.1 - 0.00047 19.8 12.9 0.085 12.8 0.1 6.0 7 0 0 7 7 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EIW83769.1 - 0.0007 19.6 0.0 0.016 15.3 0.0 2.7 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EIW83769.1 - 0.0011 18.4 2.3 1.4 8.6 0.2 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIW83769.1 - 0.0021 17.7 0.6 3.9 7.5 0.1 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF982 PF06169.7 EIW83769.1 - 0.022 14.4 0.2 9.6 6.0 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF982) TPR_21 PF09976.4 EIW83769.1 - 0.12 12.2 5.5 0.35 10.8 1.1 3.3 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIW83769.1 - 0.2 11.5 0.9 8.3 6.4 0.0 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIW83769.1 - 1.1 9.8 10.2 2.2 8.9 0.1 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat Epimerase PF01370.16 EIW83770.1 - 0.002 17.5 0.0 0.002 17.5 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EIW83770.1 - 0.037 13.9 0.1 0.041 13.7 0.1 1.1 1 0 0 1 1 1 0 short chain dehydrogenase MFS_1 PF07690.11 EIW83771.1 - 2.6e-30 105.3 23.3 2.6e-30 105.3 16.2 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW83771.1 - 7.7e-05 21.4 26.1 0.00026 19.6 18.1 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter DUF373 PF04123.8 EIW83771.1 - 0.68 8.8 3.4 1.6 7.7 2.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2663 PF10864.3 EIW83772.1 - 0.18 12.0 0.3 0.66 10.1 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2663) NACHT PF05729.7 EIW83773.1 - 6.8e-06 25.8 0.1 8.5e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW83773.1 - 8.9e-06 25.8 0.1 1.1e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 EIW83773.1 - 6.4e-05 22.1 0.0 7.9e-05 21.8 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin APS_kinase PF01583.15 EIW83773.1 - 0.0012 18.5 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase PRK PF00485.13 EIW83773.1 - 0.0013 18.2 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.1 EIW83773.1 - 0.0013 18.8 0.0 0.0015 18.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIW83773.1 - 0.002 18.4 0.0 0.0022 18.3 0.0 1.2 1 0 0 1 1 1 1 ABC transporter MobB PF03205.9 EIW83773.1 - 0.0023 17.6 0.0 0.0027 17.4 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EIW83773.1 - 0.0024 17.3 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 EIW83773.1 - 0.004 17.3 0.0 0.0048 17.0 0.0 1.2 1 0 0 1 1 1 1 RNA helicase Arch_ATPase PF01637.13 EIW83773.1 - 0.0041 16.8 0.0 0.0043 16.7 0.0 1.0 1 0 0 1 1 1 1 Archaeal ATPase NTPase_1 PF03266.10 EIW83773.1 - 0.0059 16.3 0.0 0.0069 16.1 0.0 1.1 1 0 0 1 1 1 1 NTPase T2SE PF00437.15 EIW83773.1 - 0.0074 15.2 0.0 0.0082 15.0 0.0 1.1 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF258 PF03193.11 EIW83773.1 - 0.0085 15.2 0.0 0.0085 15.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF258 UPF0079 PF02367.12 EIW83773.1 - 0.012 15.2 0.0 0.012 15.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 EIW83773.1 - 0.018 14.5 0.0 0.018 14.5 0.0 1.1 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_33 PF13671.1 EIW83773.1 - 0.02 14.7 0.0 0.023 14.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EIW83773.1 - 0.032 13.8 0.0 0.038 13.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EIW83773.1 - 0.036 12.9 0.0 0.037 12.8 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain TrwB_AAD_bind PF10412.4 EIW83773.1 - 0.049 12.2 0.0 0.057 12.0 0.0 1.1 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain ArgK PF03308.11 EIW83773.1 - 0.05 12.3 0.0 0.058 12.1 0.0 1.1 1 0 0 1 1 1 0 ArgK protein AAA_19 PF13245.1 EIW83773.1 - 0.054 13.2 0.0 0.071 12.8 0.0 1.2 1 0 0 1 1 1 0 Part of AAA domain KaiC PF06745.8 EIW83773.1 - 0.077 12.1 0.0 0.094 11.8 0.0 1.1 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 EIW83773.1 - 0.11 12.7 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EIW83773.1 - 0.12 11.7 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain GPI-anchored PF10342.4 EIW83775.1 - 4.4e-05 23.8 0.2 5.8e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Beta-lactamase PF00144.19 EIW83776.1 - 2.8e-47 161.3 1.1 5.1e-47 160.4 0.8 1.3 1 0 0 1 1 1 1 Beta-lactamase DUF155 PF02582.9 EIW83779.1 - 8.7e-42 142.9 0.0 1.2e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Asp PF00026.18 EIW83782.1 - 3.1e-84 282.9 2.5 3.6e-84 282.7 1.7 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW83782.1 - 8e-06 25.8 0.9 0.00011 22.1 0.6 2.3 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIW83782.1 - 0.0094 15.5 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EIW83782.1 - 0.011 16.2 1.0 0.68 10.4 0.1 2.7 2 1 0 2 2 2 0 Aspartyl protease zf-RVT PF13966.1 EIW83783.1 - 0.0047 17.2 0.1 0.0069 16.6 0.1 1.3 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF2975 PF11188.3 EIW83784.1 - 2.5 7.8 10.0 0.8 9.4 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) Actin PF00022.14 EIW83785.1 - 6.2e-44 149.9 0.0 3.9e-42 144.0 0.0 3.1 1 1 0 1 1 1 1 Actin CsbD PF05532.7 EIW83787.1 - 4.4e-15 55.0 18.4 1.1e-09 37.7 2.7 2.1 1 1 1 2 2 2 2 CsbD-like PB1 PF00564.19 EIW83788.1 - 0.23 11.1 0.1 2.1 8.1 0.0 2.3 2 0 0 2 2 2 0 PB1 domain Aldo_ket_red PF00248.16 EIW83789.1 - 1.2e-67 227.6 0.0 1.4e-67 227.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Semialdhyde_dh PF01118.19 EIW83789.1 - 0.072 13.4 0.0 0.59 10.4 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Aldo_ket_red PF00248.16 EIW83790.1 - 2.4e-69 233.3 0.0 2.7e-69 233.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EIW83791.1 - 1e-67 227.9 0.1 1.2e-67 227.7 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family AAA PF00004.24 EIW83792.1 - 9.7e-91 300.8 0.0 2.5e-45 153.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIW83792.1 - 3.2e-14 52.5 0.0 5.1e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EIW83792.1 - 1.8e-11 44.1 0.0 2e-05 24.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIW83792.1 - 2.3e-11 43.9 0.1 0.0028 17.7 0.0 4.8 3 2 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EIW83792.1 - 2.7e-11 44.3 0.2 7.7e-07 29.9 0.0 3.2 3 2 0 3 3 2 2 AAA domain AAA_16 PF13191.1 EIW83792.1 - 7.2e-10 39.1 10.9 0.00035 20.6 0.1 4.6 4 2 0 4 4 4 2 AAA ATPase domain TIP49 PF06068.8 EIW83792.1 - 1.3e-09 37.3 0.0 6.2e-05 21.8 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_5 PF07728.9 EIW83792.1 - 8e-09 35.3 0.5 0.012 15.3 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EIW83792.1 - 1e-08 35.1 0.0 0.0013 18.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EIW83792.1 - 1.9e-08 34.4 0.0 0.0048 16.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.7 EIW83792.1 - 4.3e-08 32.4 0.0 0.011 14.8 0.0 3.2 4 0 0 4 4 3 2 Zeta toxin Mg_chelatase PF01078.16 EIW83792.1 - 5.6e-08 32.1 0.6 0.0024 17.0 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EIW83792.1 - 2e-07 30.6 2.0 0.0031 17.2 0.1 3.5 2 2 0 2 2 2 2 Part of AAA domain AAA_25 PF13481.1 EIW83792.1 - 4e-07 29.6 4.2 0.87 8.9 0.0 5.0 2 2 2 5 5 5 1 AAA domain RNA_helicase PF00910.17 EIW83792.1 - 5.5e-07 29.7 0.0 0.011 15.8 0.0 2.7 2 1 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 EIW83792.1 - 9.5e-07 28.9 0.0 0.026 14.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EIW83792.1 - 1.4e-06 27.8 0.2 0.023 14.1 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein ABC_tran PF00005.22 EIW83792.1 - 3.9e-06 27.1 0.0 0.13 12.5 0.0 2.8 2 0 0 2 2 2 2 ABC transporter NACHT PF05729.7 EIW83792.1 - 2.8e-05 23.8 1.5 0.11 12.1 0.1 3.8 4 1 0 5 5 4 2 NACHT domain AAA_18 PF13238.1 EIW83792.1 - 6.6e-05 23.2 0.1 0.06 13.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EIW83792.1 - 7.6e-05 22.3 0.0 0.034 13.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EIW83792.1 - 0.00021 20.4 0.6 1.1 8.3 0.0 3.1 2 1 1 3 3 3 2 KaiC Sigma54_activat PF00158.21 EIW83792.1 - 0.0003 20.3 0.0 1.4 8.3 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain SKI PF01202.17 EIW83792.1 - 0.0011 18.8 0.0 1 9.2 0.0 2.6 2 0 0 2 2 2 1 Shikimate kinase PhoH PF02562.11 EIW83792.1 - 0.0014 17.9 0.5 1.6 7.9 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein Sigma54_activ_2 PF14532.1 EIW83792.1 - 0.0016 18.5 0.0 2.6 8.1 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 EIW83792.1 - 0.0016 18.4 0.0 0.023 14.6 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family Vps4_C PF09336.5 EIW83792.1 - 0.0031 17.3 0.1 4.9 7.1 0.0 2.8 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Viral_helicase1 PF01443.13 EIW83792.1 - 0.0048 16.4 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.1 EIW83792.1 - 0.0049 16.4 0.1 2.5 7.6 0.0 2.6 3 0 0 3 3 2 1 AAA domain DUF815 PF05673.8 EIW83792.1 - 0.0052 15.7 0.0 0.5 9.2 0.0 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF815) NB-ARC PF00931.17 EIW83792.1 - 0.0066 15.3 0.2 1.1 7.9 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain Parvo_NS1 PF01057.12 EIW83792.1 - 0.0073 15.2 0.1 1.2 7.9 0.0 2.1 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Rad17 PF03215.10 EIW83792.1 - 0.01 14.5 0.0 0.38 9.3 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AFG1_ATPase PF03969.11 EIW83792.1 - 0.013 14.2 0.3 2.7 6.7 0.0 3.2 3 0 0 3 3 3 0 AFG1-like ATPase UPF0079 PF02367.12 EIW83792.1 - 0.016 14.8 0.1 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Arch_ATPase PF01637.13 EIW83792.1 - 0.025 14.2 0.0 7.2 6.2 0.0 2.9 2 1 1 3 3 3 0 Archaeal ATPase DUF2075 PF09848.4 EIW83792.1 - 0.033 13.1 0.0 2.1 7.2 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.1 EIW83792.1 - 0.06 12.9 0.6 7.1 6.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EIW83792.1 - 0.088 12.5 0.0 11 5.7 0.0 2.7 2 0 0 2 2 2 0 NTPase DUF258 PF03193.11 EIW83792.1 - 0.095 11.8 0.7 26 3.9 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function, DUF258 SRPRB PF09439.5 EIW83792.1 - 0.11 11.6 0.0 14 4.8 0.0 2.5 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EIW83792.1 - 0.12 11.8 0.0 18 4.7 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EIW83792.1 - 0.28 10.4 0.2 8.4 5.6 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B Aminotran_1_2 PF00155.16 EIW83793.1 - 2.4e-38 132.0 0.0 3.2e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EIW83793.1 - 0.022 13.0 0.0 0.029 12.6 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Pkinase PF00069.20 EIW83794.1 - 1.2e-36 126.1 0.0 2.3e-36 125.3 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW83794.1 - 1.1e-10 40.9 0.0 6.3e-08 31.9 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase PTCB-BRCT PF12738.2 EIW83796.1 - 1.6e-38 130.3 0.0 1.7e-14 53.3 0.0 3.4 3 0 0 3 3 3 3 twin BRCT domain BRCT PF00533.21 EIW83796.1 - 6.1e-31 106.3 0.0 8.3e-09 35.4 0.0 4.3 4 0 0 4 4 4 3 BRCA1 C Terminus (BRCT) domain DUF605 PF04652.11 EIW83796.1 - 8.6 5.6 26.8 5.7 6.2 1.3 2.4 2 0 0 2 2 2 0 Vta1 like Pkinase PF00069.20 EIW83797.1 - 8.1e-41 139.8 0.0 2.2e-40 138.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW83797.1 - 7.4e-11 41.6 0.0 3.9e-08 32.6 0.0 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.17 EIW83797.1 - 0.14 11.4 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FAD_binding_3 PF01494.14 EIW83799.1 - 1.4e-16 60.5 0.2 4.1e-15 55.6 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EIW83799.1 - 1.5e-11 43.7 1.9 3.4e-06 26.2 1.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW83799.1 - 1e-06 27.8 0.1 1.7e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIW83799.1 - 2.5e-06 27.4 1.3 9.7e-06 25.5 0.5 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIW83799.1 - 2.7e-06 27.6 3.9 5.9e-05 23.3 0.7 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW83799.1 - 2.3e-05 23.0 0.3 8.8e-05 21.1 0.2 1.8 1 1 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EIW83799.1 - 0.0001 22.2 1.2 0.00022 21.1 0.9 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EIW83799.1 - 0.00035 20.1 0.0 0.0007 19.1 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 EIW83799.1 - 0.0065 15.1 1.0 0.011 14.4 0.3 1.6 1 1 1 2 2 2 1 Tryptophan halogenase GIDA PF01134.17 EIW83799.1 - 0.0069 15.2 2.3 0.01 14.6 1.6 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EIW83799.1 - 0.013 14.4 0.1 0.097 11.5 0.1 2.2 3 0 0 3 3 3 0 Lycopene cyclase protein FAD_oxidored PF12831.2 EIW83799.1 - 0.018 14.1 0.6 0.033 13.2 0.4 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 EIW83799.1 - 0.043 12.9 0.1 0.075 12.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 EIW83799.1 - 0.084 12.9 0.4 0.23 11.5 0.3 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MBOAT PF03062.14 EIW83800.1 - 8.5e-41 140.1 18.6 1.7e-40 139.1 12.9 1.5 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family CK_II_beta PF01214.13 EIW83801.1 - 3.1e-72 241.9 0.0 3.6e-72 241.7 0.0 1.0 1 0 0 1 1 1 1 Casein kinase II regulatory subunit FmdA_AmdA PF03069.10 EIW83802.1 - 9.7e-139 462.1 0.0 1.2e-138 461.8 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family Sdh_cyt PF01127.17 EIW83803.1 - 1.7e-23 82.7 0.5 2.2e-23 82.3 0.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Cons_hypoth698 PF03601.9 EIW83805.1 - 0.01 14.4 1.1 0.015 13.9 0.4 1.5 2 0 0 2 2 2 0 Conserved hypothetical protein 698 NAD_binding_10 PF13460.1 EIW83806.1 - 0.0039 17.2 0.1 0.021 14.8 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding GMC_oxred_N PF00732.14 EIW83808.1 - 2.3e-56 191.1 0.0 2.8e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIW83808.1 - 1.8e-33 115.8 0.2 3.5e-33 114.9 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase RicinB_lectin_2 PF14200.1 EIW83809.1 - 0.00017 21.9 3.0 0.1 12.9 0.1 2.0 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ribosomal_L2_C PF03947.13 EIW83810.1 - 0.069 12.9 0.2 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 Ribosomal Proteins L2, C-terminal domain Whi5 PF08528.6 EIW83811.1 - 0.0056 16.2 0.1 0.0098 15.4 0.1 1.3 1 0 0 1 1 1 1 Whi5 like DUF4560 PF15118.1 EIW83815.1 - 0.024 14.4 0.1 0.054 13.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4560) Reticulon PF02453.12 EIW83815.1 - 1.4 8.4 8.9 5.5 6.5 1.1 3.3 3 1 0 3 3 3 0 Reticulon Sugar_tr PF00083.19 EIW83817.1 - 5.3e-94 315.3 27.6 6e-94 315.1 19.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW83817.1 - 2.7e-21 75.6 43.1 1.3e-19 70.1 10.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily GMC_oxred_N PF00732.14 EIW83818.1 - 1.7e-64 217.7 0.0 2.3e-64 217.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIW83818.1 - 4.9e-37 127.4 0.0 8.4e-37 126.6 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIW83818.1 - 1.3e-06 27.6 0.0 0.00026 20.0 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW83818.1 - 0.00014 20.8 0.0 0.0028 16.5 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EIW83818.1 - 0.00016 20.7 0.0 0.00025 20.0 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EIW83818.1 - 0.00034 20.5 0.0 0.0015 18.4 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EIW83818.1 - 0.0014 18.7 0.0 0.86 9.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW83818.1 - 0.0042 16.9 0.0 0.0097 15.7 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIW83818.1 - 0.034 13.9 0.1 0.089 12.5 0.0 1.7 1 1 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EIW83818.1 - 0.063 11.9 0.0 0.11 11.0 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.12 EIW83818.1 - 0.074 12.1 0.0 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EIW83818.1 - 0.098 11.1 0.0 0.15 10.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein p450 PF00067.17 EIW83819.1 - 1.4e-09 37.0 0.6 3.5e-09 35.7 0.4 1.6 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW83820.1 - 6.2e-36 123.9 0.0 7.4e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3421 PF11901.3 EIW83823.1 - 8.3e-18 64.2 0.0 1.7e-15 56.8 0.0 1.7 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) eIF3_N PF09440.5 EIW83824.1 - 1.9e-44 151.0 3.1 9.1e-44 148.8 1.0 2.4 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EIW83824.1 - 6.3e-08 32.8 0.0 1.8e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EIW83824.1 - 0.033 13.9 0.2 0.25 11.1 0.0 2.4 3 0 0 3 3 3 0 COP9 signalosome, subunit CSN8 PQ-loop PF04193.9 EIW83825.1 - 3.2e-23 81.0 0.8 5.3e-11 41.9 0.3 2.4 2 0 0 2 2 2 2 PQ loop repeat DUF754 PF05449.6 EIW83825.1 - 7.3 6.6 9.2 8.9 6.4 1.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF754) F-box PF00646.28 EIW83828.1 - 0.00099 18.6 0.1 0.0024 17.4 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW83828.1 - 0.0029 17.2 0.4 0.0069 16.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like Zn_clus PF00172.13 EIW83829.1 - 0.16 11.8 6.4 0.27 11.1 4.5 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain OAS1_C PF10421.4 EIW83830.1 - 0.091 12.2 0.3 0.16 11.4 0.2 1.3 1 0 0 1 1 1 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus PAT1 PF09770.4 EIW83831.1 - 5 5.2 10.4 6 4.9 7.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-B_box PF00643.19 EIW83832.1 - 0.05 13.5 3.8 0.16 11.8 2.6 2.0 1 0 0 1 1 1 0 B-box zinc finger SP2 PF03014.9 EIW83834.1 - 0.22 9.3 7.5 0.32 8.8 5.2 1.2 1 0 0 1 1 1 0 Structural protein 2 Tet_JBP PF12851.2 EIW83835.1 - 7e-12 44.9 0.0 8.2e-12 44.7 0.0 1.0 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily F-box-like PF12937.2 EIW83838.1 - 7.1e-08 32.0 0.5 5.7e-07 29.1 0.3 2.5 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 EIW83838.1 - 0.01 15.5 0.3 2.7 7.7 0.1 2.7 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.2 EIW83839.1 - 0.054 13.2 0.1 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 F-box-like GATA PF00320.22 EIW83840.1 - 1.4e-14 53.0 3.1 2.9e-14 52.1 2.1 1.5 1 0 0 1 1 1 1 GATA zinc finger Trypan_PARP PF05887.6 EIW83840.1 - 0.001 18.8 10.3 0.001 18.8 7.1 6.0 3 2 3 6 6 6 1 Procyclic acidic repetitive protein (PARP) RhoGAP PF00620.22 EIW83845.1 - 3.2e-39 133.9 0.1 4.7e-39 133.4 0.1 1.2 1 0 0 1 1 1 1 RhoGAP domain DUF1708 PF08101.6 EIW83845.1 - 0.005 15.7 0.0 0.0065 15.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1708) Glyco_hydro_17 PF00332.13 EIW83847.1 - 2.3e-05 23.5 3.4 2.3e-05 23.5 2.3 2.2 1 1 1 2 2 2 1 Glycosyl hydrolases family 17 ETRAMP PF09716.5 EIW83847.1 - 0.0066 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) DUF3186 PF11382.3 EIW83847.1 - 0.18 10.8 1.7 3.2 6.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3186) DUF3154 PF11351.3 EIW83848.1 - 0.28 10.9 2.3 0.43 10.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) Cyt-b5 PF00173.23 EIW83849.1 - 4.9e-19 67.9 0.0 5.8e-19 67.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain F-box-like PF12937.2 EIW83850.1 - 0.089 12.5 0.2 0.21 11.3 0.1 1.6 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.2 EIW83851.1 - 7.2e-07 28.8 1.1 7.9e-06 25.4 0.1 3.0 2 1 0 2 2 2 1 F-box-like Hyaluronidase_1 PF07212.6 EIW83855.1 - 0.66 8.9 4.2 0.75 8.7 2.9 1.1 1 0 0 1 1 1 0 Hyaluronidase protein (HylP) GMC_oxred_N PF00732.14 EIW83858.1 - 1.1e-67 228.3 0.0 1.4e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIW83858.1 - 2.4e-38 131.6 0.2 3.8e-38 131.0 0.2 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIW83858.1 - 2.6e-06 26.5 0.1 7.5e-05 21.7 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW83858.1 - 6.3e-06 25.2 0.7 0.0014 17.5 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EIW83858.1 - 5.1e-05 22.3 0.1 8.2e-05 21.6 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EIW83858.1 - 0.00014 21.7 0.0 0.0004 20.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIW83858.1 - 0.0037 17.1 0.0 0.0099 15.7 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW83858.1 - 0.0091 16.0 0.0 5.5 7.0 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW83858.1 - 0.021 13.9 0.0 0.046 12.8 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 EIW83858.1 - 0.05 12.2 0.0 0.074 11.6 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EIW83858.1 - 0.058 13.1 0.4 0.17 11.6 0.2 1.9 1 1 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EIW83858.1 - 0.066 11.6 0.0 0.11 10.9 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Xpo1 PF08389.7 EIW83859.1 - 1.2e-17 64.1 3.7 1.2e-16 60.9 0.0 4.2 5 1 0 5 5 5 1 Exportin 1-like protein HEAT_2 PF13646.1 EIW83859.1 - 0.012 15.9 1.3 4.4 7.6 0.0 4.4 4 0 0 4 4 4 0 HEAT repeats DUF95 PF01944.12 EIW83859.1 - 0.082 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF95 HEAT PF02985.17 EIW83859.1 - 1.1 9.4 4.1 4 7.7 0.1 3.9 4 1 1 5 5 5 0 HEAT repeat F-box PF00646.28 EIW83860.1 - 3.6e-07 29.6 0.2 7.6e-07 28.6 0.2 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW83860.1 - 4.2e-07 29.5 0.5 9.6e-07 28.4 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EIW83860.1 - 0.083 12.6 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 F-box-like domain Cullin PF00888.17 EIW83862.1 - 2.9e-150 501.6 0.0 4.3e-150 501.0 0.0 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EIW83862.1 - 1.1e-28 98.8 1.8 3.7e-28 97.1 0.9 2.2 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF3421 PF11901.3 EIW83863.1 - 4.1e-12 45.8 0.0 2.1e-06 27.4 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF3421) zf-C2H2 PF00096.21 EIW83864.1 - 5.3e-12 45.3 6.4 0.0017 18.5 0.1 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW83864.1 - 2.6e-08 33.6 8.6 0.0078 16.4 0.1 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIW83864.1 - 5.1e-05 23.3 16.9 0.0048 17.1 1.5 3.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EIW83864.1 - 8.6e-05 22.5 0.2 0.0085 16.2 0.0 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIW83864.1 - 0.00033 20.7 0.4 0.027 14.6 0.0 2.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EIW83864.1 - 0.0022 18.0 5.7 0.17 12.0 1.4 2.6 2 1 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 EIW83864.1 - 0.0059 16.7 6.7 0.23 11.7 0.3 3.6 3 0 0 3 3 3 1 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 EIW83864.1 - 0.24 11.5 6.7 1.7 8.7 0.3 2.9 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 EIW83864.1 - 2.4 7.9 7.4 7.5 6.4 0.2 3.2 1 1 2 3 3 3 0 BED zinc finger WLM PF08325.5 EIW83865.1 - 1.9e-06 27.8 0.0 2.6e-06 27.4 0.0 1.1 1 0 0 1 1 1 1 WLM domain Sec15 PF04091.7 EIW83868.1 - 0.22 10.8 0.0 0.33 10.2 0.0 1.2 1 0 0 1 1 1 0 Exocyst complex subunit Sec15-like Flavin_Reduct PF01613.13 EIW83869.1 - 2.4e-06 27.4 0.0 3.7e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain O-antigen_lig PF13425.1 EIW83870.1 - 9.7 6.1 15.5 1.2 9.0 2.4 2.9 2 1 0 2 2 2 0 O-antigen ligase like membrane protein DnaJ PF00226.26 EIW83871.1 - 3.1e-23 81.2 4.5 5e-23 80.6 3.1 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EIW83871.1 - 2.5e-18 65.7 0.0 1.6e-17 63.1 0.0 2.3 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EIW83871.1 - 1.5e-15 56.9 15.7 2.5e-15 56.2 10.9 1.4 1 0 0 1 1 1 1 DnaJ central domain Lar_restr_allev PF14354.1 EIW83871.1 - 0.017 15.4 7.8 0.21 11.9 0.2 2.8 1 1 1 2 2 2 0 Restriction alleviation protein Lar DZR PF12773.2 EIW83871.1 - 1.1 9.1 11.2 3.6 7.4 0.8 2.2 1 1 0 1 1 1 0 Double zinc ribbon Strabismus PF06638.6 EIW83872.1 - 0.28 9.4 0.9 0.43 8.8 0.7 1.1 1 0 0 1 1 1 0 Strabismus protein BRO1 PF03097.13 EIW83874.1 - 1.4e-88 297.2 1.1 2.3e-88 296.4 0.8 1.4 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EIW83874.1 - 9.4e-72 241.4 12.0 1.4e-71 240.8 8.3 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV RasGAP PF00616.14 EIW83875.1 - 3.7e-54 183.3 3.2 5.5e-54 182.8 0.0 2.6 3 1 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EIW83875.1 - 1.4e-34 118.8 1.1 1.4e-34 118.8 0.7 2.2 2 0 0 2 2 2 1 RasGAP C-terminus KxDL PF10241.4 EIW83875.1 - 0.0015 18.3 0.3 0.078 12.8 0.2 3.2 2 0 0 2 2 2 1 Uncharacterized conserved protein DUF972 PF06156.8 EIW83875.1 - 0.004 17.4 2.1 2.7 8.3 0.2 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF972) Asp PF00026.18 EIW83876.1 - 1e-48 166.2 2.4 1.4e-48 165.8 1.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW83876.1 - 1.6e-09 37.9 0.7 3.5e-09 36.8 0.5 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIW83876.1 - 0.035 14.5 0.6 0.48 10.9 0.1 2.9 2 1 0 2 2 2 0 Aspartyl protease WLM PF08325.5 EIW83877.1 - 4.6e-53 179.8 4.8 2.8e-52 177.3 3.3 2.0 1 1 0 1 1 1 1 WLM domain DUF45 PF01863.12 EIW83877.1 - 8.3e-07 28.9 0.3 1.4e-06 28.2 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 zf-RanBP PF00641.13 EIW83877.1 - 0.0001 21.2 2.3 0.00019 20.4 1.6 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others SprT-like PF10263.4 EIW83877.1 - 0.00078 19.1 0.1 0.0017 18.0 0.0 1.6 1 0 0 1 1 1 1 SprT-like family GATase PF00117.23 EIW83878.1 - 8.9e-05 22.0 0.0 0.0004 19.9 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EIW83878.1 - 0.05 13.2 0.0 0.22 11.0 0.0 1.9 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain zf-C2H2 PF00096.21 EIW83879.1 - 3.8e-10 39.4 9.7 0.00019 21.5 0.6 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW83879.1 - 1.5e-06 28.0 15.0 0.0074 16.5 0.9 4.1 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIW83879.1 - 9.2e-05 22.5 19.1 0.0035 17.5 2.2 4.0 4 0 0 4 4 4 2 Zinc-finger double domain zf-H2C2_5 PF13909.1 EIW83879.1 - 0.0012 18.9 10.9 0.37 11.0 0.4 3.7 3 0 0 3 3 3 2 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 EIW83879.1 - 0.0018 18.3 0.1 0.16 12.1 0.1 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIW83879.1 - 0.0031 17.6 3.5 0.032 14.4 0.1 2.9 3 0 0 3 3 3 1 Zinc-finger of C2H2 type zf-Di19 PF05605.7 EIW83879.1 - 0.0058 16.7 9.5 1.4 9.1 3.3 2.9 2 1 1 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_6 PF13912.1 EIW83879.1 - 0.35 10.8 0.2 0.35 10.8 0.1 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EIW83879.1 - 0.37 10.9 11.0 1.4 9.0 0.5 3.0 1 1 2 3 3 3 0 C2H2 type zinc-finger (2 copies) IBR PF01485.16 EIW83879.1 - 6.9 6.6 9.5 1.1 9.2 1.7 2.6 2 1 1 3 3 3 0 IBR domain Cytochrom_c3_2 PF14537.1 EIW83879.1 - 8.4 6.8 11.3 5.8e+02 0.9 7.9 2.4 1 1 0 1 1 1 0 Cytochrome c3 Arylesterase PF01731.15 EIW83883.1 - 0.00014 21.7 0.0 0.001 18.9 0.0 2.4 2 1 0 2 2 2 1 Arylesterase SGL PF08450.7 EIW83883.1 - 0.00044 19.7 0.0 0.0013 18.1 0.0 1.7 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region Lactonase PF10282.4 EIW83883.1 - 0.036 13.1 0.0 0.057 12.4 0.0 1.2 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Str_synth PF03088.11 EIW83883.1 - 0.056 13.4 0.0 0.26 11.3 0.0 2.1 3 0 0 3 3 3 0 Strictosidine synthase KilA-N PF04383.8 EIW83884.1 - 0.01 15.4 0.0 0.058 13.0 0.0 2.0 1 1 0 1 1 1 0 KilA-N domain PFK PF00365.15 EIW83885.1 - 2.7e-161 535.1 2.0 5.2e-96 320.9 0.0 3.1 3 0 0 3 3 3 3 Phosphofructokinase PapJ PF14855.1 EIW83885.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Pilus-assembly fibrillin subunit, chaperone Arylesterase PF01731.15 EIW83886.1 - 0.00012 22.0 0.0 0.00074 19.4 0.0 2.3 2 1 0 2 2 2 1 Arylesterase SGL PF08450.7 EIW83886.1 - 0.0023 17.3 0.0 0.005 16.2 0.0 1.5 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EIW83886.1 - 0.065 13.2 0.0 0.3 11.1 0.0 2.1 3 0 0 3 3 3 0 Strictosidine synthase U79_P34 PF03064.11 EIW83887.1 - 6.7 6.1 9.4 0.29 10.6 2.2 1.7 1 1 0 2 2 2 0 HSV U79 / HCMV P34 CFEM PF05730.6 EIW83888.1 - 0.043 13.6 4.7 0.063 13.1 3.3 1.3 1 0 0 1 1 1 0 CFEM domain Asp PF00026.18 EIW83889.1 - 1.4e-80 270.9 10.7 1.7e-80 270.6 7.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW83889.1 - 1.5e-05 25.0 1.9 0.00016 21.6 1.2 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIW83889.1 - 0.0078 15.7 0.0 0.016 14.7 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Abhydrolase_6 PF12697.2 EIW83890.1 - 1.9e-51 175.1 3.7 6.4e-27 94.9 0.6 2.1 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW83890.1 - 4.2e-27 94.6 0.0 9.5e-13 48.1 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIW83890.1 - 3.4e-16 58.8 0.0 1e-06 28.4 0.0 2.5 2 0 0 2 2 2 2 Putative lysophospholipase Abhydrolase_1 PF00561.15 EIW83890.1 - 7.5e-09 35.4 0.0 0.0021 17.6 0.0 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.8 EIW83890.1 - 4.1e-07 29.6 0.0 0.041 13.3 0.0 2.8 2 1 1 3 3 3 2 Serine hydrolase (FSH1) Thioesterase PF00975.15 EIW83890.1 - 1.7e-06 28.4 0.1 0.011 16.0 0.0 2.4 2 0 0 2 2 2 2 Thioesterase domain Chlorophyllase2 PF12740.2 EIW83890.1 - 4.4e-06 25.7 0.2 0.024 13.5 0.0 2.8 2 2 0 2 2 2 2 Chlorophyllase enzyme Lipase_3 PF01764.20 EIW83890.1 - 1.1e-05 25.0 0.2 0.033 13.7 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) DUF900 PF05990.7 EIW83890.1 - 1.4e-05 24.5 0.0 0.055 12.7 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF900) DLH PF01738.13 EIW83890.1 - 7.5e-05 22.1 0.0 0.08 12.2 0.0 3.2 2 1 0 2 2 2 1 Dienelactone hydrolase family DUF2305 PF10230.4 EIW83890.1 - 7.8e-05 22.2 0.0 0.32 10.3 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 EIW83890.1 - 0.00027 20.5 0.0 0.053 13.1 0.0 2.3 2 0 0 2 2 2 1 PGAP1-like protein Esterase PF00756.15 EIW83890.1 - 0.00049 19.5 0.0 0.13 11.7 0.0 2.4 2 0 0 2 2 2 1 Putative esterase Chlorophyllase PF07224.6 EIW83890.1 - 0.0043 15.9 0.1 0.39 9.4 0.0 2.4 2 1 0 2 2 2 1 Chlorophyllase UPF0150 PF03681.10 EIW83890.1 - 0.042 13.4 1.2 1.1 8.9 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0150) LCAT PF02450.10 EIW83890.1 - 0.093 11.6 0.2 8.9 5.1 0.0 2.2 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Wyosine_form PF08608.7 EIW83890.1 - 0.095 12.8 0.0 19 5.4 0.0 2.8 2 1 0 2 2 2 0 Wyosine base formation Peptidase_S9 PF00326.16 EIW83890.1 - 0.12 11.5 0.0 1.8 7.7 0.0 2.7 2 2 0 2 2 2 0 Prolyl oligopeptidase family DUF3089 PF11288.3 EIW83890.1 - 0.14 11.2 0.1 2.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) PAF-AH_p_II PF03403.8 EIW83890.1 - 0.17 10.1 0.1 4.3 5.5 0.0 2.9 4 0 0 4 4 4 0 Platelet-activating factor acetylhydrolase, isoform II MIF4G PF02854.14 EIW83891.1 - 1.5e-55 187.8 0.5 1.7e-55 187.6 0.4 1.0 1 0 0 1 1 1 1 MIF4G domain Condensin2nSMC PF12422.3 EIW83891.1 - 0.013 15.1 0.3 0.087 12.5 0.0 2.1 2 0 0 2 2 2 0 Condensin II non structural maintenance of chromosomes subunit Transpep_BrtH PF14399.1 EIW83891.1 - 0.015 14.5 0.2 0.038 13.2 0.1 1.7 1 1 0 1 1 1 0 NlpC/p60-like transpeptidase DDE_1 PF03184.14 EIW83892.1 - 5.7e-11 41.9 0.0 7e-11 41.6 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease MIF4G PF02854.14 EIW83893.1 - 6.9e-05 22.3 0.0 9.4e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 MIF4G domain MIF4G PF02854.14 EIW83894.1 - 6.1e-25 87.8 0.1 7.8e-25 87.5 0.1 1.1 1 0 0 1 1 1 1 MIF4G domain MIF4G PF02854.14 EIW83895.1 - 5.1e-51 173.0 0.1 6.3e-51 172.7 0.1 1.1 1 0 0 1 1 1 1 MIF4G domain DUF4041 PF13250.1 EIW83895.1 - 0.087 12.3 0.2 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4041) Na_Ca_ex PF01699.19 EIW83896.1 - 2.7e-41 140.4 30.6 9.3e-24 83.6 5.8 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Cauli_VI PF01693.11 EIW83898.1 - 0.026 14.5 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Caulimovirus viroplasmin Abhydrolase_6 PF12697.2 EIW83900.1 - 4.9e-23 82.2 4.4 5.7e-23 81.9 3.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW83900.1 - 1.3e-11 44.4 0.1 2.2e-11 43.7 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIW83900.1 - 1.3e-07 31.3 0.1 8.2e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase Chlorophyllase2 PF12740.2 EIW83900.1 - 0.082 11.7 0.0 0.16 10.8 0.0 1.5 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_1 PF00561.15 EIW83900.1 - 0.1 12.1 0.2 0.37 10.3 0.1 2.0 2 1 0 2 2 2 0 alpha/beta hydrolase fold Chlorophyllase PF07224.6 EIW83900.1 - 0.14 10.8 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase MIF4G PF02854.14 EIW83901.1 - 4.9e-45 153.5 0.1 7.2e-45 152.9 0.1 1.3 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EIW83901.1 - 4.4e-18 64.9 0.0 1.3e-17 63.4 0.0 1.8 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 MIF4G PF02854.14 EIW83902.1 - 6.6e-47 159.6 0.2 1.2e-46 158.8 0.1 1.4 1 0 0 1 1 1 1 MIF4G domain GYF PF02213.11 EIW83902.1 - 5.7e-16 57.8 0.2 1.5e-15 56.4 0.0 1.8 2 0 0 2 2 2 1 GYF domain MA3 PF02847.12 EIW83902.1 - 8.6e-08 31.8 0.1 2.8e-07 30.2 0.0 1.9 1 0 0 1 1 1 1 MA3 domain DDE_1 PF03184.14 EIW83902.1 - 0.0043 16.2 0.0 0.0075 15.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Costars PF14705.1 EIW83902.1 - 0.14 12.1 0.0 29 4.7 0.0 2.6 2 0 0 2 2 2 0 Costars Abhydrolase_6 PF12697.2 EIW83903.1 - 6.2e-23 81.8 1.1 8.1e-23 81.4 0.8 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW83903.1 - 1.7e-11 44.0 0.0 2.4e-11 43.5 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIW83903.1 - 4.7e-07 29.5 0.0 1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 EIW83903.1 - 0.02 15.1 0.1 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_1 PF00561.15 EIW83903.1 - 0.047 13.2 0.2 0.3 10.6 0.1 2.3 2 1 0 2 2 2 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 EIW83903.1 - 0.099 11.5 0.0 0.2 10.4 0.0 1.6 1 1 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.20 EIW83903.1 - 0.13 11.9 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.2 EIW83904.1 - 0.077 12.8 0.0 0.096 12.5 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1295 PF06966.7 EIW83905.1 - 1.2e-44 152.3 0.0 1.6e-44 152.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 EIW83905.1 - 0.00032 19.3 0.1 0.0012 17.4 0.1 1.9 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.9 EIW83905.1 - 0.001 19.2 0.0 0.0037 17.4 0.0 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIW83905.1 - 0.0097 16.0 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase Myb_DNA-binding PF00249.26 EIW83906.1 - 0.023 14.7 0.7 0.042 13.9 0.5 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIW83906.1 - 0.16 12.1 0.9 0.31 11.1 0.6 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain TAP_C PF03943.8 EIW83907.1 - 3.5e-11 42.3 0.3 7.3e-11 41.3 0.2 1.6 1 0 0 1 1 1 1 TAP C-terminal domain NTF2 PF02136.15 EIW83907.1 - 8.5e-07 29.3 0.0 2.7e-05 24.5 0.0 2.3 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain UBA_4 PF14555.1 EIW83907.1 - 0.00068 19.1 0.5 0.0023 17.4 0.2 2.1 2 0 0 2 2 2 1 UBA-like domain LRR_4 PF12799.2 EIW83907.1 - 0.01 15.4 8.8 0.04 13.5 2.6 2.6 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) Ank_4 PF13637.1 EIW83908.1 - 7.3e-23 80.5 1.4 1.7e-07 31.5 0.0 6.4 4 2 1 6 6 6 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EIW83908.1 - 3.6e-21 74.7 3.0 2.4e-07 30.7 0.0 5.8 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIW83908.1 - 3.9e-20 71.9 0.2 1.6e-09 37.9 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EIW83908.1 - 8.6e-17 60.0 4.3 1e-09 37.7 0.1 6.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_3 PF13606.1 EIW83908.1 - 1.1e-13 49.9 0.9 0.0014 18.6 0.0 6.6 6 0 0 6 6 6 3 Ankyrin repeat Vps39_1 PF10366.4 EIW83909.1 - 7.5e-31 106.3 0.0 1.4e-29 102.3 0.0 2.8 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EIW83909.1 - 7.9e-23 80.7 0.1 1.6e-22 79.7 0.1 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 EIW83909.1 - 1.7e-09 37.3 0.0 6.9e-06 25.7 0.1 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS TPR_19 PF14559.1 EIW83909.1 - 3.6e-05 23.9 1.8 0.051 13.9 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat CNH PF00780.17 EIW83909.1 - 3.9e-05 23.2 0.0 8.3e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 CNH domain TPR_16 PF13432.1 EIW83909.1 - 0.0024 18.4 4.7 0.75 10.5 0.2 3.8 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIW83909.1 - 0.0025 18.2 2.8 11 6.9 0.2 4.7 4 1 0 4 4 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EIW83909.1 - 0.0039 17.2 0.3 0.1 12.7 0.0 2.8 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EIW83909.1 - 0.016 14.9 0.3 45 4.1 0.0 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIW83909.1 - 0.028 14.0 1.0 4.8 6.8 0.1 3.5 2 1 1 3 3 3 0 TPR repeat TPR_1 PF00515.23 EIW83909.1 - 0.1 12.2 2.9 24 4.7 0.2 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIW83909.1 - 0.21 11.5 5.0 14 5.9 0.0 4.0 2 1 1 3 3 3 0 Tetratricopeptide repeat COesterase PF00135.23 EIW83910.1 - 2.5e-91 307.0 0.0 3.3e-91 306.6 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW83910.1 - 2.2e-06 27.3 0.0 3.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIW83910.1 - 0.016 14.4 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DGCR6 PF07324.6 EIW83910.1 - 0.045 13.2 0.0 0.064 12.7 0.0 1.1 1 0 0 1 1 1 0 DiGeorge syndrome critical region 6 (DGCR6) protein SPA PF08616.5 EIW83911.1 - 2e-06 27.4 0.0 3.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis RRM_6 PF14259.1 EIW83912.1 - 1.2e-05 25.1 0.0 2.3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIW83912.1 - 4.3e-05 23.0 0.0 7.1e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Med3 PF11593.3 EIW83912.1 - 0.17 11.0 9.0 0.33 10.1 6.2 1.4 1 1 0 1 1 1 0 Mediator complex subunit 3 fungal SPT2 PF08243.6 EIW83913.1 - 2.5e-13 50.3 11.9 2.5e-13 50.3 8.2 5.2 4 1 1 5 5 5 1 SPT2 chromatin protein MFS_1 PF07690.11 EIW83914.1 - 6.4e-34 117.2 51.1 1.3e-29 103.0 16.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily COX2-transmemb PF09125.5 EIW83914.1 - 0.0089 15.5 2.8 0.017 14.6 0.0 2.5 2 0 0 2 2 2 1 Cytochrome C oxidase subunit II, transmembrane Amidohydro_1 PF01979.15 EIW83917.1 - 3e-58 198.0 0.6 4.4e-58 197.5 0.4 1.3 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 EIW83917.1 - 7.8e-55 184.2 1.6 8.3e-55 184.1 0.3 1.7 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EIW83917.1 - 1.5e-40 137.0 0.0 3.6e-40 135.8 0.0 1.7 1 0 0 1 1 1 1 Urease beta subunit Urease_gamma PF00547.13 EIW83917.1 - 1.3e-37 127.7 0.0 3e-37 126.5 0.0 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 EIW83917.1 - 1.8e-08 34.0 2.1 5.5e-08 32.5 1.4 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EIW83917.1 - 0.0023 17.2 0.1 0.23 10.6 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family DUF566 PF04484.7 EIW83918.1 - 2.7 7.4 11.7 3.5 7.0 8.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Mito_carr PF00153.22 EIW83919.1 - 2.8e-55 184.0 3.3 1e-19 70.0 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Nit_Regul_Hom PF10126.4 EIW83919.1 - 0.075 12.8 0.2 17 5.2 0.0 3.1 3 0 0 3 3 3 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII Methyltransf_16 PF10294.4 EIW83920.1 - 1.7e-17 63.4 0.0 3.7e-17 62.3 0.0 1.5 1 1 0 1 1 1 1 Putative methyltransferase Arrestin_N PF00339.24 EIW83921.1 - 0.0082 15.9 0.2 0.045 13.5 0.1 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EIW83921.1 - 0.014 15.5 0.0 0.025 14.6 0.0 1.3 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain Nucleoporin_FG PF13634.1 EIW83922.1 - 4.6e-23 81.6 205.2 7.4e-09 35.8 30.9 4.3 1 1 4 5 5 5 5 Nucleoporin FG repeat region DUF3947 PF13135.1 EIW83922.1 - 0.0091 16.1 2.0 0.023 14.9 1.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3947) RE_LlaMI PF09562.5 EIW83922.1 - 0.71 8.9 3.7 1.6 7.8 1.1 2.4 1 1 2 3 3 3 0 LlaMI restriction endonuclease Mitofilin PF09731.4 EIW83923.1 - 8.4e-113 378.0 13.9 1e-112 377.7 9.6 1.0 1 0 0 1 1 1 1 Mitochondrial inner membrane protein ATG22 PF11700.3 EIW83924.1 - 3.7e-117 391.7 22.7 6.4e-117 390.9 15.8 1.4 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like Trehalase PF01204.13 EIW83925.1 - 4.7e-166 553.4 0.1 5.7e-166 553.1 0.1 1.0 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EIW83925.1 - 1.6e-11 43.2 0.1 2.8e-11 42.5 0.1 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain AAA_10 PF12846.2 EIW83925.1 - 0.088 12.2 0.0 5.2 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain Lipase_3 PF01764.20 EIW83926.1 - 1.2e-07 31.4 0.0 2.6e-07 30.3 0.0 1.6 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EIW83926.1 - 0.082 12.6 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family UPF0227 PF05728.7 EIW83926.1 - 0.083 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) PGAP1 PF07819.8 EIW83926.1 - 0.15 11.5 0.1 0.32 10.5 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein Ctf8 PF09696.5 EIW83927.1 - 3.9e-18 65.4 0.1 8.5e-18 64.3 0.0 1.5 1 1 0 1 1 1 1 Ctf8 TPR_11 PF13414.1 EIW83928.1 - 1.2e-14 53.6 2.4 1.2e-14 53.6 1.7 4.2 2 2 2 4 4 4 2 TPR repeat TPR_1 PF00515.23 EIW83928.1 - 8.1e-06 25.2 9.7 0.2 11.3 0.1 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIW83928.1 - 0.038 13.8 27.0 0.21 11.5 0.2 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.1 EIW83928.1 - 0.12 12.6 2.5 0.32 11.3 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat WD40 PF00400.27 EIW83929.1 - 1.2e-07 31.3 1.7 1.2 9.0 0.0 4.6 4 0 0 4 4 4 4 WD domain, G-beta repeat COesterase PF00135.23 EIW83930.1 - 8.6e-91 305.2 5.5 3.7e-90 303.1 3.8 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW83930.1 - 1.1e-05 25.1 0.7 3.5e-05 23.4 0.5 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW83930.1 - 0.034 13.9 0.2 0.063 13.0 0.2 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pam16 PF03656.8 EIW83931.1 - 6.7e-06 25.9 0.0 7.3e-06 25.7 0.0 1.0 1 0 0 1 1 1 1 Pam16 DnaJ PF00226.26 EIW83931.1 - 1.3e-05 24.8 0.1 1.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain MIF4G PF02854.14 EIW83932.1 - 1.5e-21 76.7 1.2 2.6e-21 76.0 0.5 1.7 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EIW83932.1 - 1.7e-20 72.7 0.1 1.9e-19 69.4 0.0 2.8 3 1 1 4 4 4 1 MA3 domain Prenyltrans_2 PF13249.1 EIW83933.1 - 0.00012 22.4 0.0 0.0039 17.5 0.1 2.4 2 0 0 2 2 2 1 Prenyltransferase-like p450 PF00067.17 EIW83934.1 - 1.8e-70 237.7 0.0 2.1e-70 237.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GSHPx PF00255.14 EIW83935.1 - 6.4e-41 138.0 0.1 8.2e-41 137.7 0.1 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EIW83935.1 - 5.6e-05 22.8 0.0 8.1e-05 22.2 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family DUF4174 PF13778.1 EIW83935.1 - 0.011 15.8 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) Redoxin PF08534.5 EIW83935.1 - 0.031 13.8 0.1 0.043 13.3 0.0 1.4 1 1 0 1 1 1 0 Redoxin Metallophos PF00149.23 EIW83937.1 - 2.1e-08 33.8 0.1 5.4e-08 32.4 0.1 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIW83937.1 - 0.01 15.6 0.0 0.015 15.0 0.0 1.4 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain FBPase_2 PF06874.6 EIW83937.1 - 0.17 9.9 0.0 0.3 9.0 0.0 1.3 1 0 0 1 1 1 0 Firmicute fructose-1,6-bisphosphatase F-box-like PF12937.2 EIW83938.1 - 6e-09 35.4 0.1 1.4e-08 34.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW83938.1 - 1.6e-06 27.6 0.0 6.4e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 F-box domain AAA PF00004.24 EIW83942.1 - 1.8e-41 141.4 0.0 3.1e-41 140.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIW83942.1 - 1.7e-06 28.2 0.1 0.0003 20.9 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EIW83942.1 - 3.9e-06 26.8 0.0 7.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EIW83942.1 - 6.9e-05 21.8 0.0 0.00012 21.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EIW83942.1 - 0.0001 22.0 0.2 0.00077 19.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIW83942.1 - 0.00035 20.6 0.0 0.0015 18.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EIW83942.1 - 0.00088 18.3 0.0 0.0017 17.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EIW83942.1 - 0.004 17.0 0.0 0.0095 15.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_3 PF07726.6 EIW83942.1 - 0.0045 16.5 0.0 0.014 15.0 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIW83942.1 - 0.0046 17.7 0.4 0.015 16.1 0.1 2.1 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EIW83942.1 - 0.0068 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW83942.1 - 0.0073 16.0 0.3 0.015 14.9 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EIW83942.1 - 0.011 15.1 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.1 EIW83942.1 - 0.012 15.5 0.3 0.044 13.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EIW83942.1 - 0.013 14.6 0.2 0.26 10.3 0.1 2.2 1 1 1 2 2 2 0 KaiC AAA_18 PF13238.1 EIW83942.1 - 0.015 15.5 0.2 0.037 14.3 0.0 1.8 2 0 0 2 2 1 0 AAA domain NACHT PF05729.7 EIW83942.1 - 0.02 14.5 0.1 0.44 10.1 0.1 2.4 1 1 1 2 2 2 0 NACHT domain Viral_helicase1 PF01443.13 EIW83942.1 - 0.035 13.6 0.0 0.057 12.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 EIW83942.1 - 0.037 13.4 0.9 2 7.7 0.2 2.5 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.17 EIW83942.1 - 0.038 12.8 0.0 0.068 12.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Zeta_toxin PF06414.7 EIW83942.1 - 0.045 12.8 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin TIP49 PF06068.8 EIW83942.1 - 0.067 11.8 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus DUF2075 PF09848.4 EIW83942.1 - 0.079 11.9 0.1 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RNA_helicase PF00910.17 EIW83942.1 - 0.091 12.9 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 EIW83942.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EIW83942.1 - 0.14 11.7 0.2 0.39 10.2 0.2 1.7 1 0 0 1 1 1 0 AAA domain Yip1 PF04893.12 EIW83943.1 - 3e-13 49.6 15.8 4.2e-13 49.1 11.0 1.2 1 0 0 1 1 1 1 Yip1 domain DUF4199 PF13858.1 EIW83943.1 - 0.022 14.6 1.1 0.022 14.6 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Med26 PF08711.6 EIW83945.1 - 1.2e-09 37.5 0.0 2.7e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Pkinase PF00069.20 EIW83947.1 - 1.8e-06 27.2 0.0 2.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Choline_kinase PF01633.15 EIW83947.1 - 0.013 15.1 0.0 0.02 14.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 EIW83947.1 - 0.034 13.8 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.12 EIW83947.1 - 0.071 12.1 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase p450 PF00067.17 EIW83948.1 - 1.3e-24 86.5 0.0 1.5e-24 86.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW83949.1 - 4.2e-68 229.9 0.0 3.4e-52 177.5 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.17 EIW83950.1 - 1.2e-81 274.5 0.0 1.5e-81 274.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Totivirus_coat PF05518.6 EIW83951.1 - 6 4.5 7.6 11 3.7 5.3 1.4 1 0 0 1 1 1 0 Totivirus coat protein CRAL_TRIO PF00650.15 EIW83952.1 - 6.9e-18 64.6 0.0 1.3e-17 63.7 0.0 1.5 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EIW83952.1 - 1.2e-08 34.9 2.5 1.7e-08 34.4 0.4 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO PF00650.15 EIW83953.1 - 2.3e-30 105.1 0.0 3.1e-30 104.7 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EIW83953.1 - 5.1e-07 29.7 0.1 1e-06 28.7 0.1 1.5 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EIW83953.1 - 0.053 13.4 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Abhydrolase_1 PF00561.15 EIW83954.1 - 1.8e-29 102.9 0.0 2.5e-29 102.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EIW83954.1 - 2.2e-26 93.1 0.0 3.2e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW83954.1 - 1.5e-13 50.7 0.0 1.4e-12 47.5 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EIW83954.1 - 0.0021 17.8 0.0 0.0045 16.8 0.0 1.6 1 1 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 EIW83954.1 - 0.038 12.4 0.0 0.053 11.9 0.0 1.3 1 0 0 1 1 1 0 Ndr family Herpes_UL79 PF03049.9 EIW83954.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 UL79 family Sad1_UNC PF07738.8 EIW83955.1 - 3.8e-20 72.0 0.0 7.3e-09 35.5 0.0 2.7 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal FTCD_C PF04961.7 EIW83955.1 - 0.017 14.5 0.2 0.017 14.5 0.1 1.8 2 0 0 2 2 2 0 Formiminotransferase-cyclodeaminase Metallophos PF00149.23 EIW83956.1 - 2.8e-42 144.3 1.0 3.5e-42 144.0 0.7 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Homez PF11569.3 EIW83956.1 - 0.091 11.8 0.4 0.18 10.8 0.3 1.4 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez cwf21 PF08312.7 EIW83956.1 - 0.13 12.0 0.8 0.28 11.0 0.6 1.5 1 0 0 1 1 1 0 cwf21 domain Cpn60_TCP1 PF00118.19 EIW83957.1 - 7e-143 476.7 1.1 8e-143 476.5 0.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Oxidored_molyb PF00174.14 EIW83958.1 - 8.8e-44 148.8 0.1 1.4e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EIW83958.1 - 4.3e-15 55.4 2.6 5.4e-15 55.1 0.4 2.0 2 0 0 2 2 2 1 Mo-co oxidoreductase dimerisation domain BNR PF02012.15 EIW83958.1 - 0.026 14.3 0.5 0.12 12.3 0.3 2.2 1 0 0 1 1 1 0 BNR/Asp-box repeat ADH_N PF08240.7 EIW83959.1 - 4.2e-24 84.4 1.0 8.7e-24 83.3 0.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW83959.1 - 1.8e-15 56.6 0.0 2.9e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIW83959.1 - 0.00013 21.1 0.3 0.00025 20.2 0.1 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 EIW83959.1 - 0.00015 22.6 0.0 0.00037 21.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.10 EIW83959.1 - 0.0026 17.6 0.1 0.0053 16.6 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 EIW83959.1 - 0.0046 17.4 0.0 0.8 10.2 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold AlaDh_PNT_C PF01262.16 EIW83959.1 - 0.0064 16.0 0.1 0.011 15.3 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 EIW83959.1 - 0.0085 16.2 0.0 0.014 15.5 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EIW83959.1 - 0.081 12.5 0.1 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ADH_N PF08240.7 EIW83960.1 - 4.7e-25 87.4 1.7 1e-24 86.3 1.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW83960.1 - 1.2e-13 50.7 0.0 2.1e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIW83960.1 - 0.00019 20.6 0.1 0.00033 19.8 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EIW83960.1 - 0.0055 16.2 0.1 0.011 15.2 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EIW83960.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EIW83960.1 - 0.017 15.0 0.1 0.065 13.0 0.1 1.9 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase ThiF PF00899.16 EIW83960.1 - 0.05 13.4 0.4 0.086 12.6 0.3 1.3 1 0 0 1 1 1 0 ThiF family ADH_N PF08240.7 EIW83961.1 - 9.8e-21 73.5 0.9 1.9e-20 72.6 0.6 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW83961.1 - 2.9e-12 46.2 0.0 9.8e-12 44.5 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIW83961.1 - 2.2e-05 23.7 0.0 3.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EIW83961.1 - 0.0061 16.4 0.0 0.0098 15.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EIW83961.1 - 0.019 14.5 0.1 0.03 13.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 EIW83961.1 - 0.042 13.6 1.3 0.076 12.8 0.9 1.3 1 0 0 1 1 1 0 ThiF family AlaDh_PNT_C PF01262.16 EIW83961.1 - 0.044 13.3 0.2 0.096 12.2 0.1 1.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Fer4_4 PF12800.2 EIW83961.1 - 3.6 8.1 5.3 1.5 9.3 1.4 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain eIF-5_eIF-2B PF01873.12 EIW83963.1 - 2e-41 140.5 0.0 3.7e-41 139.6 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EIW83963.1 - 6.1e-31 106.2 1.5 1.2e-30 105.3 0.2 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon NmrA PF05368.8 EIW83964.1 - 4.1e-07 29.4 0.4 6e-07 28.9 0.3 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EIW83964.1 - 3.5e-06 26.6 0.3 0.05 13.0 0.1 2.4 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EIW83964.1 - 2.1e-05 24.8 0.1 3.9e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EIW83964.1 - 3.4e-05 22.8 0.2 0.0015 17.5 0.0 2.8 3 0 0 3 3 3 1 Male sterility protein NAD_binding_10 PF13460.1 EIW83964.1 - 4.1e-05 23.6 0.3 8e-05 22.7 0.2 1.5 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIW83964.1 - 0.00056 18.6 0.3 0.053 12.2 0.2 2.3 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EIW83964.1 - 0.00081 18.4 0.3 0.0012 17.8 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EIW83964.1 - 0.00081 19.3 0.1 0.0016 18.4 0.1 1.4 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.12 EIW83964.1 - 0.001 19.4 0.2 0.0026 18.1 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 EIW83964.1 - 0.015 15.1 4.8 0.27 11.1 2.0 2.8 2 1 0 2 2 2 0 short chain dehydrogenase Peripla_BP_6 PF13458.1 EIW83964.1 - 0.023 14.0 0.2 0.069 12.4 0.0 1.8 2 0 0 2 2 2 0 Periplasmic binding protein KR PF08659.5 EIW83964.1 - 0.031 13.9 0.7 0.12 12.0 0.5 1.9 1 1 1 2 2 2 0 KR domain PIN_2 PF10130.4 EIW83971.1 - 0.2 11.6 4.1 0.064 13.2 0.6 1.8 2 0 0 2 2 2 0 PIN domain Borrelia_P83 PF05262.6 EIW83973.1 - 1.1 7.4 4.9 1.4 7.1 3.4 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein TEX15 PF15326.1 EIW83973.1 - 1.2 8.7 5.1 0.13 11.9 0.5 1.5 2 0 0 2 2 2 0 Testis expressed sequence 15 GPI-anchored PF10342.4 EIW83975.1 - 5.9e-07 29.8 0.9 1e-06 29.1 0.6 1.3 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family PRMT5 PF05185.11 EIW83976.1 - 2.2e-159 531.1 0.0 2.7e-159 530.8 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.2 EIW83976.1 - 0.029 14.9 0.0 0.062 13.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EIW83976.1 - 0.064 13.7 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 EIW83976.1 - 0.072 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Ank_5 PF13857.1 EIW83977.1 - 3.5e-12 46.1 0.1 5.6e-11 42.3 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EIW83977.1 - 9.3e-12 44.1 0.2 8.6e-08 31.6 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EIW83977.1 - 3.8e-11 43.1 0.0 7.7e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIW83977.1 - 4e-11 43.1 0.1 7.8e-08 32.6 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIW83977.1 - 1e-08 34.5 0.0 5.3e-06 26.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat DUF2359 PF10151.4 EIW83977.1 - 0.05 12.1 0.0 0.063 11.7 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2359) DUF4404 PF14357.1 EIW83977.1 - 0.37 11.2 3.3 17 5.9 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) GATA PF00320.22 EIW83978.1 - 2.9e-14 52.0 4.2 8e-14 50.7 2.9 1.8 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.5 EIW83978.1 - 7e-06 26.0 0.1 1.4e-05 25.0 0.1 1.4 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EIW83978.1 - 0.0087 15.8 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EIW83978.1 - 0.19 12.1 0.0 0.37 11.1 0.0 1.4 1 0 0 1 1 1 0 PAS domain EHN PF06441.7 EIW83979.1 - 1.5e-21 76.4 0.0 3.9e-21 75.0 0.0 1.7 2 0 0 2 2 2 1 Epoxide hydrolase N terminus LRR_4 PF12799.2 EIW83980.1 - 2.3e-40 135.5 41.7 1.4e-09 37.3 4.0 7.2 3 3 2 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW83980.1 - 2.4e-30 104.0 51.0 1.4e-09 37.5 5.0 5.4 3 2 3 6 6 6 6 Leucine rich repeat LRR_9 PF14580.1 EIW83980.1 - 1.4e-17 63.8 8.9 3.6e-08 33.1 1.1 3.8 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.28 EIW83980.1 - 2e-16 57.4 34.4 0.58 10.3 0.2 11.0 11 0 0 11 11 11 9 Leucine Rich Repeat LRR_6 PF13516.1 EIW83980.1 - 2.7e-16 57.7 23.9 0.27 11.4 0.2 10.4 8 1 2 10 10 10 8 Leucine Rich repeat LRR_7 PF13504.1 EIW83980.1 - 5.8e-12 43.7 22.2 0.93 9.9 0.1 10.3 9 1 1 10 10 10 3 Leucine rich repeat DUF4078 PF13300.1 EIW83981.1 - 1.4e-14 53.9 3.6 1.4e-14 53.9 2.5 3.3 2 1 1 3 3 3 2 Domain of unknown function (DUF4078) DUF2203 PF09969.4 EIW83981.1 - 0.086 13.0 3.7 0.33 11.1 0.0 2.7 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) Lactamase_B PF00753.22 EIW83982.1 - 9.5e-12 44.9 3.4 7.4e-11 42.0 2.4 2.1 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EIW83982.1 - 0.00014 21.5 0.0 0.00023 20.7 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain FAD_binding_3 PF01494.14 EIW83983.1 - 8e-20 71.1 0.2 2.7e-19 69.4 0.1 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIW83983.1 - 2.9e-07 29.7 5.1 5.6e-06 25.4 2.6 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW83983.1 - 5e-07 29.6 1.8 1.4e-06 28.1 1.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EIW83983.1 - 9.1e-06 24.5 1.9 0.0022 16.6 0.4 2.3 2 0 0 2 2 2 2 Tryptophan halogenase Amino_oxidase PF01593.19 EIW83983.1 - 0.00017 20.8 0.4 0.13 11.3 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 EIW83983.1 - 0.00037 19.7 1.5 0.0005 19.2 1.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW83983.1 - 0.00041 20.6 1.8 0.0012 19.2 1.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW83983.1 - 0.00057 19.8 0.4 0.0014 18.5 0.3 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EIW83983.1 - 0.0023 16.7 0.0 0.005 15.7 0.0 1.5 1 1 0 1 1 1 1 Squalene epoxidase HI0933_like PF03486.9 EIW83983.1 - 0.0035 15.8 2.3 0.0035 15.8 1.6 1.5 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EIW83983.1 - 0.01 14.7 1.8 0.01 14.7 1.2 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Thi4 PF01946.12 EIW83983.1 - 0.018 14.1 1.9 0.02 13.9 0.5 1.7 2 0 0 2 2 2 0 Thi4 family ApbA PF02558.11 EIW83983.1 - 0.033 13.6 0.3 0.075 12.4 0.2 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 EIW83983.1 - 0.036 14.1 1.1 0.09 12.8 0.7 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW83983.1 - 0.043 12.6 3.2 0.087 11.6 2.2 1.5 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EIW83983.1 - 0.047 12.5 1.3 0.25 10.2 0.2 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 EIW83983.1 - 0.05 13.3 2.7 0.31 10.7 0.4 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EIW83983.1 - 0.083 12.5 1.2 0.2 11.2 0.9 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Syndecan PF01034.15 EIW83983.1 - 0.14 11.7 0.2 0.32 10.6 0.2 1.6 1 0 0 1 1 1 0 Syndecan domain p450 PF00067.17 EIW83984.1 - 1.4e-48 165.5 0.0 1.7e-33 115.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.17 EIW83985.1 - 5.7e-71 239.4 0.0 7.2e-71 239.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 CENP-H PF05837.7 EIW83986.1 - 0.012 15.7 0.1 0.012 15.7 0.0 1.0 1 0 0 1 1 1 0 Centromere protein H (CENP-H) FliJ PF02050.11 EIW83986.1 - 0.017 15.1 0.3 0.019 15.0 0.2 1.0 1 0 0 1 1 1 0 Flagellar FliJ protein DUF1470 PF07336.6 EIW83986.1 - 0.039 14.2 2.9 0.041 14.2 2.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1470) TMP_2 PF06791.8 EIW83986.1 - 0.054 13.0 0.0 0.059 12.9 0.0 1.0 1 0 0 1 1 1 0 Prophage tail length tape measure protein Spc7 PF08317.6 EIW83986.1 - 0.069 11.8 0.1 0.071 11.7 0.1 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein IncA PF04156.9 EIW83986.1 - 0.15 11.6 0.7 0.15 11.6 0.5 1.0 1 0 0 1 1 1 0 IncA protein PEP-utilisers_N PF05524.8 EIW83986.1 - 0.2 11.4 1.6 0.23 11.2 1.1 1.1 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal KfrA_N PF11740.3 EIW83986.1 - 0.4 11.1 3.2 0.43 11.0 2.2 1.1 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term zf-C2HC5 PF06221.8 EIW83987.1 - 3.5e-12 45.8 5.2 6e-12 45.1 3.6 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type DUF566 PF04484.7 EIW83987.1 - 9.6 5.6 6.5 8.4 5.7 1.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF566) CS PF04969.11 EIW83988.1 - 0.00014 22.3 0.0 0.00026 21.4 0.0 1.4 1 0 0 1 1 1 1 CS domain TPR_2 PF07719.12 EIW83988.1 - 0.067 13.1 1.8 0.91 9.5 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat THUMP PF02926.12 EIW83989.1 - 1.1e-12 48.0 0.2 2.7e-12 46.7 0.1 1.7 1 1 1 2 2 2 1 THUMP domain HLH PF00010.21 EIW83990.1 - 5.4e-07 29.1 0.0 1.4e-06 27.9 0.0 1.7 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain AATF-Che1 PF13339.1 EIW83990.1 - 0.00097 19.3 2.1 0.0015 18.6 0.7 1.7 1 1 1 2 2 2 1 Apoptosis antagonizing transcription factor BUD22 PF09073.5 EIW83990.1 - 8.8 5.2 13.7 0.33 9.9 4.1 1.9 2 0 0 2 2 2 0 BUD22 His_Phos_2 PF00328.17 EIW83991.1 - 1.3e-36 126.7 0.0 1.5e-36 126.4 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) NUDIX PF00293.23 EIW83992.1 - 8.6e-13 48.0 0.4 1.2e-12 47.6 0.3 1.1 1 0 0 1 1 1 1 NUDIX domain DUF3833 PF12915.2 EIW83992.1 - 0.13 11.5 0.1 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3833) Zip PF02535.17 EIW83993.1 - 7.4e-51 173.0 14.6 1e-44 152.8 4.8 2.1 1 1 1 2 2 2 2 ZIP Zinc transporter HD PF01966.17 EIW83994.1 - 4e-06 26.8 0.2 1.1e-05 25.3 0.2 1.7 1 1 0 1 1 1 1 HD domain ADH_zinc_N_2 PF13602.1 EIW83995.1 - 1.5e-14 54.9 0.1 5e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EIW83995.1 - 2.2e-09 36.9 0.0 4.8e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW83995.1 - 3.5e-07 29.9 0.0 6.4e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain K_trans PF02705.11 EIW83995.1 - 0.028 12.7 0.0 0.042 12.2 0.0 1.2 1 0 0 1 1 1 0 K+ potassium transporter PEX11 PF05648.9 EIW83996.1 - 6e-12 45.3 0.2 8.9e-11 41.4 0.1 2.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) HTH_Tnp_IS630 PF01710.11 EIW83996.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Transposase DUF427 PF04248.7 EIW83997.1 - 9.4e-37 124.5 0.1 1.2e-27 95.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF427) DSS1_SEM1 PF05160.8 EIW83998.1 - 5.5e-20 70.9 10.2 1.4e-19 69.5 7.1 1.7 1 1 0 1 1 1 1 DSS1/SEM1 family Sugar_tr PF00083.19 EIW83999.1 - 1.6e-34 119.2 36.0 2e-22 79.4 5.8 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EIW83999.1 - 1.8e-17 63.0 49.2 5.1e-13 48.4 16.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIW83999.1 - 0.0011 17.4 2.4 0.0011 17.4 1.7 2.9 1 1 1 2 2 2 1 MFS/sugar transport protein PT-TG PF14449.1 EIW83999.1 - 0.021 14.5 0.2 0.069 12.9 0.1 1.9 1 0 0 1 1 1 0 Pre-toxin TG Pkinase PF00069.20 EIW84001.1 - 3.7e-35 121.3 0.0 4.3e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW84001.1 - 5.7e-12 45.2 0.0 7.3e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW84001.1 - 9.8e-05 22.1 0.0 0.4 10.3 0.0 2.2 2 0 0 2 2 2 2 Phosphotransferase enzyme family SLY PF12485.3 EIW84002.1 - 0.079 13.1 0.8 0.17 12.0 0.6 1.5 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein DUF605 PF04652.11 EIW84002.1 - 1.2 8.4 11.3 1.2 8.4 7.8 1.1 1 0 0 1 1 1 0 Vta1 like p450 PF00067.17 EIW84003.1 - 4.1e-58 197.0 0.0 5.5e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 EIW84004.1 - 4.3e-29 99.3 2.5 1.1e-06 28.3 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EIW84004.1 - 0.0022 17.7 0.2 0.11 12.1 0.0 2.7 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A ADH_zinc_N PF00107.21 EIW84005.1 - 2.7e-16 59.2 0.9 4.8e-16 58.5 0.7 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW84005.1 - 3.3e-16 60.3 0.3 8.1e-16 59.0 0.1 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW84005.1 - 1.5e-12 47.1 0.0 1.1e-09 37.9 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain FA_hydroxylase PF04116.8 EIW84006.1 - 2.1e-13 50.6 22.1 2.1e-13 50.6 15.3 2.3 2 0 0 2 2 2 2 Fatty acid hydroxylase superfamily MMR_HSR1 PF01926.18 EIW84007.1 - 5.2e-09 36.0 1.1 1e-08 35.1 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 EIW84007.1 - 3.7e-06 26.1 1.2 3.7e-06 26.1 0.9 3.2 1 1 2 3 3 2 1 AIG1 family FeoB_N PF02421.13 EIW84007.1 - 0.00016 21.0 0.1 0.00053 19.2 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EIW84007.1 - 0.00084 18.5 0.3 0.0021 17.2 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EIW84007.1 - 0.0047 16.7 0.1 0.0047 16.7 0.1 4.7 2 2 1 3 3 2 2 Dynamin family Miro PF08477.8 EIW84007.1 - 0.062 13.7 0.0 0.062 13.7 0.0 2.8 2 1 0 2 2 2 0 Miro-like protein ATP_bind_1 PF03029.12 EIW84007.1 - 0.1 12.0 1.4 1 8.8 0.6 2.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 EIW84007.1 - 0.1 12.1 0.5 0.22 11.0 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.14 EIW84007.1 - 0.13 11.7 1.4 0.21 10.9 0.0 2.2 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EIW84007.1 - 0.54 11.0 0.1 0.54 11.0 0.1 3.1 2 1 0 2 2 1 0 AAA domain Astro_capsid PF03115.9 EIW84007.1 - 6.2 4.9 12.4 7.6 4.6 8.6 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor WD40 PF00400.27 EIW84008.1 - 2.4e-26 90.6 11.3 2.3e-07 30.4 0.1 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat PD40 PF07676.7 EIW84008.1 - 0.027 14.1 0.2 4.8 6.9 0.0 3.1 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat ABC_membrane PF00664.18 EIW84009.1 - 1.6e-50 172.0 35.3 2.4e-26 92.7 13.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIW84009.1 - 5.8e-49 165.9 0.0 2.6e-27 95.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIW84009.1 - 3.4e-11 43.6 3.0 0.0063 16.5 0.0 4.0 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 EIW84009.1 - 1.1e-07 31.3 2.8 0.0042 16.3 0.1 3.9 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EIW84009.1 - 1.4e-05 24.9 2.0 0.12 12.3 0.1 3.4 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EIW84009.1 - 2e-05 24.0 0.3 0.19 11.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EIW84009.1 - 4.4e-05 22.7 0.2 0.02 14.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 EIW84009.1 - 0.00012 21.9 3.1 0.8 9.5 0.1 4.1 4 0 0 4 4 4 2 AAA domain Miro PF08477.8 EIW84009.1 - 0.00025 21.5 1.4 0.63 10.5 0.1 2.8 2 0 0 2 2 2 2 Miro-like protein MobB PF03205.9 EIW84009.1 - 0.00032 20.4 0.7 0.37 10.4 0.0 3.5 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EIW84009.1 - 0.00057 19.3 1.8 0.13 11.6 0.0 3.2 4 0 0 4 4 4 1 AAA domain AAA_10 PF12846.2 EIW84009.1 - 0.00069 19.1 0.1 0.82 9.0 0.0 2.9 3 0 0 3 3 3 2 AAA-like domain AAA_22 PF13401.1 EIW84009.1 - 0.00095 19.3 0.3 1.5 8.9 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.1 EIW84009.1 - 0.001 19.1 6.7 0.11 12.5 0.2 3.8 2 2 0 2 2 2 1 AAA ATPase domain Arch_ATPase PF01637.13 EIW84009.1 - 0.0026 17.5 0.2 0.32 10.6 0.0 3.0 2 1 0 2 2 2 1 Archaeal ATPase DUF87 PF01935.12 EIW84009.1 - 0.0028 17.4 1.1 0.073 12.8 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function DUF87 Dynamin_N PF00350.18 EIW84009.1 - 0.0036 17.1 4.3 0.21 11.4 0.7 2.6 2 0 0 2 2 2 1 Dynamin family AAA_17 PF13207.1 EIW84009.1 - 0.0036 18.0 1.2 3.1 8.6 0.0 3.1 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EIW84009.1 - 0.0042 16.2 0.6 1.2 8.1 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin FtsK_SpoIIIE PF01580.13 EIW84009.1 - 0.0085 15.5 0.2 6 6.2 0.0 3.1 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_23 PF13476.1 EIW84009.1 - 0.0089 16.3 0.0 3.2 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EIW84009.1 - 0.023 14.3 0.5 0.25 10.9 0.0 2.4 2 0 0 2 2 2 0 NACHT domain T2SE PF00437.15 EIW84009.1 - 0.036 12.9 0.2 5.9 5.7 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein UPF0079 PF02367.12 EIW84009.1 - 0.076 12.6 1.3 0.71 9.5 0.1 3.0 4 0 0 4 4 4 0 Uncharacterised P-loop hydrolase UPF0079 ArgK PF03308.11 EIW84009.1 - 0.1 11.3 3.8 3.8 6.1 0.1 2.7 3 0 0 3 3 3 0 ArgK protein ATP_bind_1 PF03029.12 EIW84009.1 - 0.11 12.0 1.4 6.5 6.2 0.1 2.9 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_13 PF13166.1 EIW84009.1 - 0.26 9.7 0.0 0.52 8.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EIW84009.1 - 0.3 10.4 3.7 1.8 7.9 0.1 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain SIR2 PF02146.12 EIW84010.1 - 8.7e-30 103.7 0.0 7.5e-20 71.3 0.0 3.0 2 1 0 2 2 2 2 Sir2 family TPP_enzyme_M PF00205.17 EIW84010.1 - 0.011 15.4 0.1 0.84 9.3 0.1 2.4 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain DUF572 PF04502.8 EIW84010.1 - 0.43 9.7 5.3 2.4 7.3 1.1 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF572) APG17 PF04108.7 EIW84011.1 - 2.7e-32 112.0 17.1 7.7e-27 94.1 6.5 2.0 2 0 0 2 2 2 2 Autophagy protein Apg17 PE PF00934.15 EIW84011.1 - 0.0031 17.5 0.1 0.015 15.3 0.0 2.1 2 0 0 2 2 2 1 PE family Sec5 PF15469.1 EIW84011.1 - 0.041 13.6 0.7 0.33 10.6 0.1 2.5 2 0 0 2 2 2 0 Exocyst complex component Sec5 DUF310 PF03750.8 EIW84011.1 - 0.095 12.8 0.7 0.29 11.3 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF310) DUF342 PF03961.8 EIW84011.1 - 0.13 10.6 5.4 0.08 11.3 1.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) NPV_P10 PF05531.7 EIW84011.1 - 0.29 11.4 10.8 3.5 7.9 0.2 4.5 3 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein GHL13 PF14883.1 EIW84011.1 - 0.31 10.1 4.8 0.5 9.4 0.3 2.4 2 1 1 3 3 3 0 Hypothetical glycosyl hydrolase family 13 FTO_CTD PF12934.2 EIW84011.1 - 0.55 9.7 3.4 2 7.9 0.1 2.9 3 1 0 3 3 3 0 FTO C-terminal domain DUF1664 PF07889.7 EIW84011.1 - 0.64 9.8 9.6 0.47 10.2 0.6 3.6 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) FH2 PF02181.18 EIW84011.1 - 1.1 8.0 6.4 1.9 7.2 1.0 2.6 1 1 2 3 3 3 0 Formin Homology 2 Domain V_ATPase_I PF01496.14 EIW84011.1 - 1.3 6.8 5.3 1.9 6.2 3.7 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2203 PF09969.4 EIW84011.1 - 1.5 9.1 7.6 0.79 9.9 0.4 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) CorA PF01544.13 EIW84011.1 - 2.3 7.1 14.4 0.28 10.1 1.9 2.4 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Laminin_II PF06009.7 EIW84011.1 - 2.3 7.9 7.5 2.5 7.8 0.1 3.5 2 1 1 4 4 4 0 Laminin Domain II Prefoldin_3 PF13758.1 EIW84011.1 - 5.1 6.9 8.3 10 5.9 0.3 3.6 3 1 1 4 4 4 0 Prefoldin subunit APG6 PF04111.7 EIW84011.1 - 9.8 5.1 14.6 4.1 6.3 3.1 2.5 1 1 1 2 2 2 0 Autophagy protein Apg6 Acyl-CoA_dh_1 PF00441.19 EIW84012.1 - 1.2e-32 113.0 1.0 1.8e-32 112.5 0.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EIW84012.1 - 6.5e-19 67.1 0.7 1.3e-18 66.2 0.5 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EIW84012.1 - 1e-17 63.6 0.1 2.9e-17 62.2 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_2 PF08028.6 EIW84012.1 - 2.1e-06 28.0 0.1 3.5e-06 27.2 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EIW84012.1 - 5.9e-06 26.8 0.0 1.9e-05 25.1 0.0 1.9 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Coprogen_oxidas PF01218.13 EIW84014.1 - 1.1e-110 368.9 0.0 2e-110 367.9 0.0 1.4 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase DUF2959 PF11172.3 EIW84014.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) LysM PF01476.15 EIW84015.1 - 4.2e-06 26.5 0.0 1.2e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 LysM domain PEP-utilisers_N PF05524.8 EIW84015.1 - 0.061 13.1 0.1 0.11 12.2 0.1 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal Acyl-CoA_dh_1 PF00441.19 EIW84016.1 - 2.8e-29 102.1 0.6 4.3e-29 101.5 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 EIW84016.1 - 3.5e-18 65.1 0.0 8.8e-18 63.8 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 EIW84016.1 - 1.7e-17 62.6 1.1 3.4e-17 61.6 0.3 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EIW84016.1 - 3.4e-12 46.9 0.0 1.5e-11 44.9 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EIW84016.1 - 4.5e-05 23.7 0.0 8.8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2945 PF11160.3 EIW84017.1 - 8.6e-06 25.4 0.0 0.034 13.9 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2945) DUF1918 PF08940.6 EIW84017.1 - 3.7e-05 22.9 0.0 5e-05 22.5 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1918) TOM13 PF08219.6 EIW84018.1 - 6.4e-13 48.2 0.0 1.9e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Outer membrane protein TOM13 Dscam_C PF12355.3 EIW84018.1 - 2.2 8.5 11.1 0.5 10.6 1.6 2.8 2 1 1 3 3 3 0 Down syndrome cell adhesion molecule C terminal NP1-WLL PF11733.3 EIW84018.1 - 2.7 8.3 8.4 0.68 10.2 3.5 1.7 2 0 0 2 2 2 0 Non-capsid protein NP1 DUF605 PF04652.11 EIW84020.1 - 0.0009 18.7 17.0 0.0012 18.3 11.8 1.2 1 0 0 1 1 1 1 Vta1 like G-patch PF01585.18 EIW84021.1 - 2.5e-06 27.1 0.2 4.2e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 G-patch domain FHA PF00498.21 EIW84021.1 - 2.5e-06 27.4 0.0 4.3e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 FHA domain Cyclin_N PF00134.18 EIW84022.1 - 2.2e-42 143.6 0.5 1.9e-41 140.5 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EIW84022.1 - 3.5e-26 91.4 0.3 5.9e-26 90.7 0.2 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain Rota_NS53 PF00981.12 EIW84022.1 - 0.032 12.8 0.6 0.17 10.5 0.2 1.9 2 0 0 2 2 2 0 Rotavirus RNA-binding Protein 53 (NS53) G-gamma PF00631.17 EIW84022.1 - 0.038 13.7 0.0 0.088 12.5 0.0 1.6 1 0 0 1 1 1 0 GGL domain adh_short PF00106.20 EIW84023.1 - 3.1e-65 219.1 10.7 4.5e-34 117.7 1.4 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EIW84023.1 - 8e-30 103.8 7.3 5.1e-16 58.8 0.8 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 EIW84023.1 - 9.6e-29 99.2 0.0 2.5e-28 97.9 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EIW84023.1 - 5.2e-11 42.4 0.0 2.1e-10 40.4 0.0 2.0 2 1 0 2 2 2 1 N-terminal half of MaoC dehydratase THF_DHG_CYH_C PF02882.14 EIW84023.1 - 0.0029 16.6 1.4 0.45 9.5 0.3 2.8 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.14 EIW84023.1 - 0.012 14.7 6.0 1 8.5 0.1 4.0 4 0 0 4 4 4 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EIW84023.1 - 0.012 15.2 0.9 0.012 15.2 0.6 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EIW84023.1 - 0.12 12.4 3.1 0.37 10.8 0.1 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.18 EIW84023.1 - 0.36 10.6 6.8 1.3 8.8 0.4 2.6 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain DUF4161 PF13722.1 EIW84023.1 - 0.38 11.0 2.4 5.3 7.3 0.1 2.5 2 0 0 2 2 2 0 C-terminal domain on CstA (DUF4161) DUF543 PF04418.7 EIW84023.1 - 4.3 7.3 9.9 12 5.9 0.9 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF543) Na_Ca_ex PF01699.19 EIW84024.1 - 4.6e-36 123.4 37.8 2.6e-19 69.2 8.9 3.2 2 1 1 3 3 3 3 Sodium/calcium exchanger protein Vma12 PF11712.3 EIW84024.1 - 0.16 11.6 1.2 2.5 7.7 0.0 2.6 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase LRR_6 PF13516.1 EIW84025.1 - 0.00024 20.8 0.0 1 9.6 0.0 3.3 3 0 0 3 3 3 2 Leucine Rich repeat F-box-like PF12937.2 EIW84025.1 - 0.0065 16.1 1.1 0.017 14.8 0.1 2.3 2 0 0 2 2 2 1 F-box-like LRR_1 PF00560.28 EIW84025.1 - 0.016 15.1 0.9 11 6.5 0.1 4.2 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 EIW84025.1 - 0.044 13.9 3.7 30 5.4 0.1 4.9 4 0 0 4 4 4 0 Leucine rich repeat LRR_4 PF12799.2 EIW84025.1 - 0.078 12.6 0.3 16 5.2 0.0 2.9 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) Erg28 PF03694.8 EIW84026.1 - 3.8e-36 123.4 4.1 4.7e-36 123.1 2.8 1.1 1 0 0 1 1 1 1 Erg28 like protein Frag1 PF10277.4 EIW84028.1 - 3.6e-36 124.6 12.9 4.4e-36 124.3 9.0 1.1 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family EI24 PF07264.6 EIW84028.1 - 0.0016 17.8 23.0 0.0034 16.8 11.9 3.0 1 1 1 2 2 2 1 Etoposide-induced protein 2.4 (EI24) DSBA PF01323.15 EIW84029.1 - 1.4e-29 103.0 0.0 1.6e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EIW84029.1 - 1.4e-05 25.1 0.1 0.00043 20.3 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_5 PF13743.1 EIW84029.1 - 0.014 14.9 0.1 0.02 14.4 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.1 EIW84029.1 - 0.03 14.1 0.1 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 Thioredoxin domain SH3_1 PF00018.23 EIW84030.1 - 5.4e-13 48.1 0.3 8.1e-13 47.5 0.2 1.3 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIW84030.1 - 7.8e-12 44.5 0.1 1.2e-11 44.0 0.1 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIW84030.1 - 3e-11 42.6 0.1 5.3e-11 41.8 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain Epimerase PF01370.16 EIW84032.1 - 8.4e-07 28.6 0.1 0.0059 16.0 0.0 2.3 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIW84032.1 - 5.3e-06 25.8 0.2 7.7e-06 25.3 0.2 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIW84032.1 - 7.8e-05 22.7 0.2 0.00012 22.1 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIW84032.1 - 0.00085 18.3 0.0 0.0015 17.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 EIW84032.1 - 0.017 15.4 0.2 0.046 14.0 0.1 1.8 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EIW84032.1 - 0.022 13.6 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EIW84032.1 - 0.1 11.2 0.0 0.26 9.9 0.0 1.6 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EIW84032.1 - 5.6 6.8 6.4 2.6 7.9 1.5 2.3 2 1 0 2 2 2 0 short chain dehydrogenase Ferritin_2 PF13668.1 EIW84033.1 - 0.00017 21.5 0.0 0.00026 20.9 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain WD40 PF00400.27 EIW84034.1 - 3.6e-49 162.9 20.1 4.2e-12 45.4 0.1 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EIW84034.1 - 3.7e-06 25.3 6.1 0.0048 15.0 3.2 3.0 2 1 0 2 2 2 2 Nucleoporin Nup120/160 DUF1513 PF07433.6 EIW84034.1 - 0.021 13.7 0.0 0.082 11.7 0.0 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) Cytochrom_D1 PF02239.11 EIW84034.1 - 0.034 12.4 0.1 0.26 9.5 0.1 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF1416 PF07210.7 EIW84034.1 - 0.093 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) Ferritin_2 PF13668.1 EIW84035.1 - 1.4e-06 28.3 0.1 1.5e-06 28.1 0.0 1.0 1 0 0 1 1 1 1 Ferritin-like domain DUF1793 PF08760.6 EIW84037.1 - 6.2e-37 127.0 0.1 1.2e-36 126.1 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Epimerase PF01370.16 EIW84038.1 - 3.8e-10 39.6 0.0 3.1e-09 36.6 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW84038.1 - 8.3e-08 32.4 0.0 9.4e-07 29.0 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EIW84038.1 - 7.1e-06 25.4 0.0 1.1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EIW84038.1 - 0.00084 19.6 0.0 0.0018 18.5 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EIW84038.1 - 0.0014 17.5 0.0 0.0038 16.2 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein 3Beta_HSD PF01073.14 EIW84038.1 - 0.024 13.3 0.0 0.097 11.3 0.0 1.8 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF742 PF05331.6 EIW84038.1 - 0.041 13.4 0.0 0.071 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF742) FAD_binding_3 PF01494.14 EIW84039.1 - 3.7e-73 246.6 0.0 4.6e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIW84039.1 - 3.5e-06 26.1 0.1 0.0045 15.9 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EIW84039.1 - 4.6e-06 25.9 0.1 2.7e-05 23.4 0.1 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW84039.1 - 9.3e-06 25.9 0.1 0.19 12.1 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIW84039.1 - 0.00011 21.0 0.1 0.0038 15.9 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 EIW84039.1 - 0.00034 20.7 0.0 0.00071 19.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW84039.1 - 0.0006 18.3 0.1 0.026 12.9 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EIW84039.1 - 0.00092 19.1 0.1 0.0024 17.7 0.1 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW84039.1 - 0.0029 17.6 0.0 0.011 15.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIW84039.1 - 0.0062 15.4 0.0 0.17 10.6 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EIW84039.1 - 0.0071 15.4 0.0 0.025 13.6 0.0 1.9 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 EIW84039.1 - 0.065 13.0 1.1 0.11 12.2 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding YtfJ_HI0045 PF09695.5 EIW84039.1 - 0.17 11.2 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (YtfJ_HI0045) DEAD PF00270.24 EIW84042.1 - 0.0066 15.9 0.0 0.0073 15.8 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase TPR_14 PF13428.1 EIW84043.1 - 0.032 14.8 0.1 0.27 11.9 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L10 PF00466.15 EIW84044.1 - 2.2e-24 85.2 1.1 7.4e-24 83.5 0.1 2.0 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EIW84044.1 - 1.2e-22 80.0 10.3 4.1e-21 75.1 5.3 2.3 2 0 0 2 2 2 2 60s Acidic ribosomal protein S19 PF06756.6 EIW84044.1 - 0.019 14.8 0.2 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 Chorion protein S19 C-terminal Glyco_transf_20 PF00982.16 EIW84045.1 - 5.9e-181 602.0 0.0 6.4e-180 598.6 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 20 Glycos_transf_1 PF00534.15 EIW84045.1 - 0.011 15.2 0.1 3.4 7.0 0.0 2.4 2 1 0 2 2 2 0 Glycosyl transferases group 1 Epimerase PF01370.16 EIW84046.1 - 2.1e-07 30.6 0.6 6.5e-06 25.7 0.2 2.5 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EIW84046.1 - 1.7e-06 27.5 0.9 2.5e-06 26.9 0.6 1.2 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EIW84046.1 - 3.1e-06 27.4 0.3 5.5e-06 26.6 0.2 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EIW84046.1 - 3.7e-05 22.5 0.8 0.00065 18.4 0.4 2.5 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIW84046.1 - 8.8e-05 22.5 0.3 0.00017 21.6 0.2 1.5 2 0 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIW84046.1 - 0.00014 20.8 1.9 0.00067 18.6 0.2 2.7 2 1 0 2 2 2 1 Male sterility protein Saccharop_dh PF03435.13 EIW84046.1 - 0.00026 20.0 0.7 0.00037 19.5 0.5 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EIW84046.1 - 0.00055 19.9 0.2 0.0011 18.9 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.12 EIW84046.1 - 0.0012 19.2 0.3 0.0024 18.2 0.2 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EIW84046.1 - 0.01 15.9 0.2 0.02 14.9 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EIW84046.1 - 0.033 13.1 0.3 0.078 11.8 0.1 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein KR PF08659.5 EIW84046.1 - 0.093 12.3 0.2 0.17 11.5 0.2 1.4 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 EIW84046.1 - 0.32 10.8 2.0 1.3 8.9 1.4 2.0 1 1 0 1 1 1 0 short chain dehydrogenase FAD_binding_3 PF01494.14 EIW84047.1 - 2.3e-73 247.2 0.0 3.1e-73 246.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EIW84047.1 - 5.3e-06 25.7 0.1 2.5e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW84047.1 - 4.3e-05 23.8 0.1 0.22 11.9 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIW84047.1 - 6.7e-05 21.6 0.8 0.0019 16.8 0.0 2.1 1 1 0 2 2 2 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 EIW84047.1 - 0.0002 21.5 0.0 0.00042 20.4 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW84047.1 - 0.00033 19.6 0.2 0.007 15.3 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIW84047.1 - 0.00049 20.0 0.3 0.0018 18.1 0.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW84047.1 - 0.0018 16.8 0.1 0.018 13.5 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EIW84047.1 - 0.002 18.0 0.0 0.0072 16.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIW84047.1 - 0.0039 16.3 0.0 0.016 14.2 0.0 2.0 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EIW84047.1 - 0.0043 15.9 0.0 0.12 11.1 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain YtfJ_HI0045 PF09695.5 EIW84047.1 - 0.028 13.7 0.0 0.06 12.6 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (YtfJ_HI0045) NAD_binding_9 PF13454.1 EIW84047.1 - 0.054 13.2 3.4 0.093 12.5 0.1 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_binding_4 PF07993.7 EIW84048.1 - 2.4e-07 29.9 0.1 1.4e-06 27.4 0.0 2.2 3 0 0 3 3 3 1 Male sterility protein NmrA PF05368.8 EIW84048.1 - 6.5e-07 28.8 0.0 9.3e-06 25.0 0.1 2.1 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.16 EIW84048.1 - 7e-07 28.9 0.1 1.1e-05 25.0 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW84048.1 - 4e-06 26.9 0.2 5.6e-06 26.4 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EIW84048.1 - 4.1e-05 23.8 0.1 9e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EIW84048.1 - 0.00011 20.9 0.1 0.00022 20.0 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EIW84048.1 - 0.00014 21.8 1.2 0.0031 17.4 0.8 2.2 1 1 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 EIW84048.1 - 0.00039 19.5 0.1 0.00057 18.9 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 EIW84048.1 - 0.00055 19.6 0.2 0.001 18.7 0.1 1.4 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EIW84048.1 - 0.0011 17.9 0.0 0.0015 17.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 EIW84048.1 - 0.0077 16.6 0.0 0.017 15.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 EIW84049.1 - 1.2e-09 38.0 0.1 3.5e-06 26.6 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW84049.1 - 2.3e-09 37.5 0.2 3.6e-09 36.9 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIW84049.1 - 2.3e-07 29.8 0.1 7.6e-07 28.1 0.1 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EIW84049.1 - 5.2e-06 26.7 0.4 1.4e-05 25.3 0.1 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 EIW84049.1 - 7.1e-06 25.4 0.2 1.2e-05 24.7 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 EIW84049.1 - 1.4e-05 24.2 0.2 2e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 EIW84049.1 - 3.1e-05 23.0 0.0 8.1e-05 21.6 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EIW84049.1 - 0.00058 18.8 0.1 0.00079 18.4 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_3 PF03447.11 EIW84049.1 - 0.0077 16.6 0.2 0.018 15.3 0.1 1.7 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain KR PF08659.5 EIW84049.1 - 0.028 14.0 0.1 0.05 13.2 0.1 1.5 1 0 0 1 1 1 0 KR domain F420_oxidored PF03807.12 EIW84049.1 - 0.033 14.6 0.1 0.074 13.4 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Ldh_1_N PF00056.18 EIW84049.1 - 0.064 13.0 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain adh_short PF00106.20 EIW84049.1 - 0.1 12.5 3.9 0.1 12.5 0.5 2.5 2 1 1 3 3 3 0 short chain dehydrogenase DapB_N PF01113.15 EIW84049.1 - 0.11 12.4 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Herpes_gE PF02480.11 EIW84050.1 - 4e-05 22.0 0.1 7.2e-05 21.2 0.0 1.4 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E SH3_1 PF00018.23 EIW84050.1 - 0.0013 18.0 0.0 0.0024 17.2 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIW84050.1 - 0.0029 17.1 0.0 0.0066 16.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain CD34_antigen PF06365.7 EIW84050.1 - 0.0052 16.4 1.6 0.01 15.4 1.1 1.5 1 1 0 1 1 1 1 CD34/Podocalyxin family DUF3481 PF11980.3 EIW84050.1 - 0.006 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3481) SID-1_RNA_chan PF13965.1 EIW84050.1 - 0.011 13.9 0.1 0.014 13.5 0.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 EphA2_TM PF14575.1 EIW84050.1 - 0.012 15.9 3.7 0.043 14.2 2.5 2.0 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain IncA PF04156.9 EIW84050.1 - 0.015 14.9 0.1 0.027 14.0 0.1 1.3 1 0 0 1 1 1 0 IncA protein Neur_chan_memb PF02932.11 EIW84050.1 - 0.026 14.4 0.1 0.04 13.7 0.1 1.3 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1191 PF06697.7 EIW84050.1 - 0.032 13.0 0.0 0.061 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Orthoreo_P10 PF07204.6 EIW84050.1 - 0.049 13.3 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 Adeno_E3_CR2 PF02439.10 EIW84050.1 - 0.057 12.9 5.4 0.091 12.3 3.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Rhabdo_glycop PF00974.13 EIW84050.1 - 0.14 10.3 0.0 0.19 9.8 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Serinc PF03348.10 EIW84050.1 - 0.17 10.5 0.3 0.24 10.0 0.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Tweety PF04906.8 EIW84050.1 - 0.21 9.9 0.3 0.29 9.5 0.2 1.1 1 0 0 1 1 1 0 Tweety TMEM154 PF15102.1 EIW84050.1 - 0.23 11.1 3.0 0.18 11.5 0.2 2.2 2 1 0 2 2 2 0 TMEM154 protein family FAM163 PF15069.1 EIW84050.1 - 7.3 7.1 8.4 17 5.9 3.1 2.5 2 1 0 2 2 2 0 FAM163 family zf-C2H2 PF00096.21 EIW84051.1 - 0.07 13.5 7.4 1 9.8 0.9 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW84051.1 - 1 9.8 8.7 12 6.5 1.3 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EIW84051.1 - 8.6 6.5 9.0 2.2 8.4 0.3 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) p450 PF00067.17 EIW84053.1 - 3e-65 220.5 0.0 6.6e-65 219.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 GST_N PF02798.15 EIW84054.1 - 2.9e-07 30.5 0.0 5.2e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EIW84054.1 - 4.4e-07 30.0 0.0 7.8e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EIW84054.1 - 1.9e-05 25.0 0.0 3.6e-05 24.1 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW84054.1 - 5.6e-05 23.0 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIW84054.1 - 0.00022 21.0 0.2 0.00053 19.8 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW84054.1 - 0.00069 19.5 0.0 0.0012 18.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW84055.1 - 2.4e-07 30.5 0.2 5.5e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW84055.1 - 4.2e-07 30.0 0.0 7.6e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW84055.1 - 1.2e-06 28.4 0.0 1.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW84055.1 - 1.6e-06 28.4 0.0 3e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EIW84055.1 - 2.6e-06 27.5 0.0 4.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW84055.1 - 0.0061 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain WD40 PF00400.27 EIW84057.1 - 2.2e-13 49.5 10.0 0.02 14.7 0.1 6.2 7 0 0 7 7 7 5 WD domain, G-beta repeat HSP9_HSP12 PF04119.7 EIW84058.1 - 2.5e-19 69.1 8.4 1e-18 67.1 4.4 2.0 2 0 0 2 2 2 1 Heat shock protein 9/12 MT0933_antitox PF14013.1 EIW84058.1 - 0.0016 18.5 4.9 0.3 11.2 0.1 2.2 2 0 0 2 2 2 2 MT0933-like antitoxin protein MOFRL PF05161.8 EIW84058.1 - 0.063 13.3 5.1 0.23 11.5 1.3 2.0 1 1 1 2 2 2 0 MOFRL family DUF3484 PF11983.3 EIW84058.1 - 0.091 13.5 0.2 3.3 8.6 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3484) DUF2370 PF10176.4 EIW84059.1 - 2.2e-60 203.9 0.0 5.7e-60 202.5 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2370) DUF2668 PF10873.3 EIW84059.1 - 4.4 7.4 6.5 0.5 10.5 1.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2668) Epimerase PF01370.16 EIW84060.1 - 1.9e-07 30.7 0.1 9.1e-07 28.5 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EIW84060.1 - 3e-06 27.5 0.4 0.00014 22.1 0.1 2.4 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 EIW84060.1 - 4e-06 26.2 1.3 6e-06 25.6 0.4 1.6 2 0 0 2 2 2 1 NmrA-like family Saccharop_dh PF03435.13 EIW84060.1 - 4.8e-06 25.7 0.2 6.8e-06 25.3 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 EIW84060.1 - 0.0001 21.3 0.9 0.00046 19.1 0.0 2.3 2 1 0 3 3 3 1 Male sterility protein 3Beta_HSD PF01073.14 EIW84060.1 - 0.00012 20.8 0.4 0.0011 17.7 0.1 2.2 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIW84060.1 - 0.00079 19.4 2.4 0.00098 19.1 0.7 1.9 2 1 0 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EIW84060.1 - 0.0008 18.3 0.1 0.0013 17.6 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 EIW84060.1 - 0.003 17.9 0.1 0.008 16.5 0.1 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EIW84060.1 - 0.0084 16.0 0.0 0.021 14.8 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 EIW84060.1 - 0.028 14.3 0.4 0.17 11.7 0.3 2.4 1 1 0 1 1 1 0 short chain dehydrogenase Peptidase_A4 PF01828.12 EIW84065.1 - 2.2e-79 265.3 17.0 2.5e-79 265.1 11.8 1.0 1 0 0 1 1 1 1 Peptidase A4 family ADK PF00406.17 EIW84065.1 - 0.037 13.8 0.0 0.062 13.1 0.0 1.3 1 0 0 1 1 1 0 Adenylate kinase VCBS PF13517.1 EIW84065.1 - 1.2 9.5 4.7 7.3 7.0 0.2 2.8 2 1 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella zf-C3HC PF07967.8 EIW84066.1 - 1.3e-22 80.0 0.0 1.9e-20 72.9 0.0 2.3 2 0 0 2 2 2 2 C3HC zinc finger-like Rsm1 PF08600.5 EIW84066.1 - 2.3e-14 53.0 0.0 6.6e-09 35.5 0.0 3.5 3 0 0 3 3 3 2 Rsm1-like BIR PF00653.16 EIW84066.1 - 0.0022 18.3 0.0 0.12 12.8 0.0 2.5 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain DM PF00751.13 EIW84066.1 - 0.22 11.0 0.4 13 5.3 0.0 2.5 2 0 0 2 2 2 0 DM DNA binding domain Caveolin PF01146.12 EIW84067.1 - 1.4 8.5 3.9 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 Caveolin Glyco_hydro_16 PF00722.16 EIW84068.1 - 6.9e-08 31.9 0.0 1.4e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Epimerase PF01370.16 EIW84069.1 - 5e-08 32.6 0.0 1.1e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EIW84069.1 - 2.4e-07 31.0 0.3 8.9e-06 26.0 0.1 2.4 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EIW84069.1 - 5.6e-06 25.5 0.1 7.8e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EIW84069.1 - 1.6e-05 24.9 1.0 3.3e-05 23.9 0.3 1.9 2 1 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EIW84069.1 - 1.8e-05 24.0 0.5 3.5e-05 23.1 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.7 EIW84069.1 - 9.8e-05 21.3 0.3 0.0012 17.8 0.0 2.4 2 1 0 3 3 3 1 Male sterility protein 3Beta_HSD PF01073.14 EIW84069.1 - 0.00027 19.7 0.1 0.0014 17.3 0.0 2.1 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EIW84069.1 - 0.0052 15.7 0.0 0.0079 15.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein F420_oxidored PF03807.12 EIW84069.1 - 0.0066 16.8 0.0 0.019 15.3 0.0 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 EIW84069.1 - 0.017 15.0 0.1 0.19 11.6 0.1 2.4 1 1 0 1 1 1 0 short chain dehydrogenase SKG6 PF08693.5 EIW84070.1 - 0.0018 17.5 1.1 0.0037 16.5 0.7 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1049 PF06305.6 EIW84070.1 - 0.01 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) Herpes_gE PF02480.11 EIW84070.1 - 0.054 11.7 0.0 0.091 11.0 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E P12 PF12669.2 EIW84070.1 - 0.14 12.3 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 Virus attachment protein p12 family Pkinase_Tyr PF07714.12 EIW84071.1 - 2.8e-47 160.9 0.0 4e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EIW84071.1 - 4.5e-42 144.0 0.0 7.5e-42 143.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EIW84071.1 - 0.00039 19.4 0.0 0.00078 18.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like ABC1 PF03109.11 EIW84071.1 - 0.0012 18.8 0.0 0.0055 16.6 0.0 2.0 2 0 0 2 2 2 1 ABC1 family RIO1 PF01163.17 EIW84071.1 - 0.0083 15.4 0.0 0.016 14.5 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EIW84071.1 - 0.01 15.6 0.2 0.062 13.0 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EIW84071.1 - 0.027 13.5 0.0 0.06 12.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EcKinase PF02958.15 EIW84071.1 - 0.049 12.7 0.1 4.8 6.2 0.0 2.4 3 0 0 3 3 3 0 Ecdysteroid kinase UPF0061 PF02696.9 EIW84072.1 - 1.3e-89 300.7 0.0 1.1e-88 297.6 0.0 2.0 1 1 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family CoA_transf_3 PF02515.12 EIW84074.1 - 7.2e-50 168.8 0.0 9.3e-50 168.5 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III CysG_dimeriser PF10414.4 EIW84074.1 - 0.0034 16.8 0.6 0.012 15.1 0.0 2.2 2 0 0 2 2 2 1 Sirohaem synthase dimerisation region F-box-like PF12937.2 EIW84076.1 - 8.3e-06 25.4 1.0 2.1e-05 24.1 0.7 1.8 1 0 0 1 1 1 1 F-box-like His_Phos_2 PF00328.17 EIW84077.1 - 3.9e-07 29.7 0.0 1.1e-05 24.9 0.0 2.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EIW84077.1 - 0.037 14.1 0.0 0.054 13.5 0.0 1.5 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) PMM PF03332.8 EIW84078.1 - 7e-107 356.0 0.3 8e-107 355.8 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EIW84078.1 - 1.3e-05 24.9 0.0 0.00034 20.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EIW84078.1 - 0.0022 17.3 0.0 1.6 7.9 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Actin PF00022.14 EIW84079.1 - 4.4e-90 301.9 0.0 6.1e-90 301.4 0.0 1.0 1 0 0 1 1 1 1 Actin Fungal_trans PF04082.13 EIW84080.1 - 4.4e-12 45.4 3.5 7.1e-12 44.7 2.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW84080.1 - 4.3e-06 26.5 9.9 7.8e-06 25.7 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SDA1 PF05285.7 EIW84080.1 - 0.019 14.2 0.6 0.031 13.5 0.4 1.2 1 0 0 1 1 1 0 SDA1 E1-E2_ATPase PF00122.15 EIW84082.1 - 3.9e-57 192.9 1.6 3.9e-57 192.9 1.1 2.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EIW84082.1 - 8.4e-46 155.7 10.6 8.4e-46 155.7 7.3 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EIW84082.1 - 1.1e-25 91.2 0.0 4.8e-25 89.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIW84082.1 - 1.7e-19 69.5 0.0 3.4e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EIW84082.1 - 9.5e-16 58.5 0.0 6e-15 55.9 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIW84082.1 - 2.5e-06 26.8 0.1 7.3e-06 25.3 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EIW84082.1 - 0.001 18.7 0.1 0.0058 16.2 0.1 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3317 PF11779.3 EIW84083.1 - 5.3e-10 38.5 1.3 7.3e-10 38.1 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Epiglycanin_C PF14654.1 EIW84083.1 - 0.005 16.8 0.0 0.0059 16.5 0.0 1.1 1 0 0 1 1 1 1 Mucin, catalytic, TM and cytoplasmic tail region Imp-YgjV PF10688.4 EIW84083.1 - 0.061 12.7 0.0 0.07 12.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial inner membrane protein YscJ_FliF_C PF08345.6 EIW84084.1 - 0.16 11.9 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Flagellar M-ring protein C-terminal SRP9-21 PF05486.7 EIW84085.1 - 0.15 11.7 0.1 5.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle 9 kDa protein (SRP9) DUF708 PF05341.6 EIW84086.1 - 0.035 13.8 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF708) SAD_SRA PF02182.12 EIW84087.1 - 4.7e-40 136.4 0.0 8.3e-40 135.6 0.0 1.4 1 0 0 1 1 1 1 SAD/SRA domain DUF3776 PF12618.3 EIW84087.1 - 0.42 11.1 7.8 1 9.9 5.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3776) MFS_1 PF07690.11 EIW84088.1 - 3.6e-40 137.7 39.7 3.6e-40 137.7 27.5 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIW84088.1 - 5.2e-13 48.0 3.5 1e-12 47.0 2.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIW84088.1 - 2.3e-12 46.2 11.6 2.3e-12 46.2 8.0 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter Serinc PF03348.10 EIW84089.1 - 2.1e-155 517.6 14.4 2.6e-155 517.3 9.9 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) DUF3661 PF12400.3 EIW84089.1 - 0.0036 17.3 0.1 0.0036 17.3 0.0 3.0 2 1 1 3 3 3 1 Vaculolar membrane protein T2SF PF00482.18 EIW84089.1 - 0.099 12.5 0.7 1.5 8.6 0.0 2.9 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F Rad51 PF08423.6 EIW84090.1 - 3.7e-09 35.8 0.0 5e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EIW84090.1 - 5.3e-06 25.9 0.0 1.9e-05 24.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain KaiC PF06745.8 EIW84090.1 - 0.00041 19.5 0.0 0.0012 18.0 0.0 1.8 1 1 0 1 1 1 1 KaiC AAA_10 PF12846.2 EIW84090.1 - 0.0013 18.2 0.0 0.0029 17.0 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain AAA_22 PF13401.1 EIW84090.1 - 0.0068 16.5 0.0 0.014 15.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EIW84090.1 - 0.013 14.4 0.0 0.016 14.2 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EIW84090.1 - 0.062 13.2 0.2 0.16 11.9 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain CobU PF02283.11 EIW84090.1 - 0.082 12.3 0.0 3.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase tRNA-synt_2 PF00152.15 EIW84091.1 - 8.7e-71 238.4 0.0 1.5e-69 234.3 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EIW84091.1 - 1e-08 34.9 0.2 1.7e-08 34.2 0.1 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Med22 PF06179.7 EIW84092.1 - 2.7e-17 62.7 2.5 3.3e-17 62.4 1.7 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex TMP-TENI PF02581.12 EIW84092.1 - 0.026 13.6 0.8 0.033 13.3 0.6 1.3 1 1 0 1 1 1 0 Thiamine monophosphate synthase/TENI PMC2NT PF08066.7 EIW84092.1 - 0.14 12.4 3.1 0.48 10.7 0.2 2.1 1 1 1 2 2 2 0 PMC2NT (NUC016) domain Cellulase PF00150.13 EIW84093.1 - 3.2e-26 92.1 12.9 4.2e-26 91.7 8.9 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EIW84093.1 - 0.00015 22.1 0.0 0.00045 20.6 0.0 1.9 1 1 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_2_C PF02836.12 EIW84093.1 - 0.0064 15.4 0.0 0.023 13.6 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 EIW84093.1 - 0.0082 15.2 0.0 0.019 14.1 0.0 1.5 1 0 0 1 1 1 1 Beta-galactosidase DUF3724 PF12521.3 EIW84093.1 - 1.5 8.6 5.9 1.8 8.4 0.7 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3724) DHDPS PF00701.17 EIW84094.1 - 2.7e-38 131.2 0.1 7.9e-38 129.6 0.0 1.6 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.1 EIW84094.1 - 0.00025 20.3 0.0 0.00035 19.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase IstB_IS21_ATP PF08483.6 EIW84094.1 - 0.23 11.1 1.0 0.28 10.8 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding N-terminal Dynamin_N PF00350.18 EIW84095.1 - 9e-44 149.2 0.0 1.6e-43 148.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EIW84095.1 - 0.00085 19.2 0.0 0.0023 17.8 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_M PF01031.15 EIW84095.1 - 0.0037 16.0 0.0 0.053 12.2 0.0 2.4 2 1 0 2 2 2 1 Dynamin central region Miro PF08477.8 EIW84095.1 - 0.0046 17.4 0.1 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EIW84095.1 - 0.018 15.0 1.3 0.86 9.5 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.1 EIW84095.1 - 0.15 11.9 0.6 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA domain SCP2 PF02036.12 EIW84096.1 - 1.5e-24 86.2 0.5 1.8e-24 85.9 0.3 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EIW84096.1 - 9.3e-08 32.0 0.2 1.3e-07 31.6 0.2 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Maf1 PF09174.5 EIW84097.1 - 1.1e-35 123.1 0.0 1.5e-28 99.8 0.0 2.7 2 1 0 2 2 2 2 Maf1 regulator Sugar_tr PF00083.19 EIW84099.1 - 3.1e-34 118.3 21.0 4.1e-34 117.9 14.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1616 PF07760.6 EIW84099.1 - 0.0095 15.1 0.3 3.5 6.6 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1616) TPR_2 PF07719.12 EIW84100.1 - 3.2e-25 85.9 13.6 0.00013 21.5 0.1 9.2 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_11 PF13414.1 EIW84100.1 - 1.7e-24 85.2 9.0 1.7e-09 37.1 0.1 6.7 6 1 1 7 7 7 4 TPR repeat TPR_1 PF00515.23 EIW84100.1 - 4.1e-22 76.8 7.4 6.1e-06 25.6 0.0 7.6 9 0 0 9 9 9 4 Tetratricopeptide repeat Apc3 PF12895.2 EIW84100.1 - 4.3e-18 65.2 11.6 1.4e-07 31.4 0.0 6.1 4 1 0 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EIW84100.1 - 3.1e-16 57.8 0.0 0.00078 19.0 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EIW84100.1 - 2.9e-15 55.9 16.5 2.2e-11 43.4 0.3 8.0 5 1 4 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIW84100.1 - 2e-13 50.5 22.9 0.00028 21.4 0.0 7.6 7 1 1 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIW84100.1 - 6e-11 41.6 6.3 0.39 11.0 0.0 8.7 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIW84100.1 - 1.2e-10 41.5 3.2 0.019 15.2 0.1 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.1 EIW84100.1 - 1.1e-07 31.5 9.0 0.0019 18.0 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIW84100.1 - 3.8e-07 29.4 13.2 0.93 9.4 0.0 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 EIW84100.1 - 5.1e-06 26.5 17.0 2.9 8.5 0.0 8.4 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIW84100.1 - 9e-06 25.8 19.8 1.9 9.3 0.0 9.2 7 3 4 11 11 10 1 Tetratricopeptide repeat TPR_9 PF13371.1 EIW84100.1 - 0.0097 15.7 11.6 0.68 9.8 0.1 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TOM20_plant PF06552.7 EIW84100.1 - 0.049 13.2 0.0 0.4 10.2 0.0 2.3 2 0 0 2 2 2 0 Plant specific mitochondrial import receptor subunit TOM20 ATP_sub_h PF10775.4 EIW84100.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 ATP synthase complex subunit h RRM_1 PF00076.17 EIW84101.1 - 5.1e-16 58.0 0.0 8.9e-16 57.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW84101.1 - 4.4e-12 45.7 0.0 7.1e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW84101.1 - 6.6e-10 38.6 0.1 9.8e-10 38.1 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CobT PF06213.7 EIW84101.1 - 3.2 6.8 15.3 2.4 7.2 9.2 1.7 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Daxx PF03344.10 EIW84101.1 - 8.9 4.6 15.3 1.2 7.5 7.6 1.6 2 0 0 2 2 2 0 Daxx Family HpaP PF09483.5 EIW84102.1 - 5 7.0 10.5 6.2 6.7 7.3 1.1 1 0 0 1 1 1 0 Type III secretion protein (HpaP) GCR1_C PF12550.3 EIW84103.1 - 7.1e-08 32.2 0.9 2.2e-07 30.6 0.6 1.8 1 1 0 1 1 1 1 Transcriptional activator of glycolytic enzymes XPG_I PF00867.13 EIW84105.1 - 3e-18 65.6 0.0 4.7e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 EIW84105.1 - 0.0059 16.1 0.0 0.016 14.7 0.0 1.8 1 1 0 1 1 1 1 XPG domain containing XPG_N PF00752.12 EIW84105.1 - 0.13 12.5 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 XPG N-terminal domain Sugar_tr PF00083.19 EIW84107.1 - 9.1e-45 153.0 16.3 1.3e-44 152.4 11.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW84107.1 - 4.6e-18 65.0 20.9 4.6e-18 65.0 14.5 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Complex1_LYR PF05347.10 EIW84108.1 - 1.6e-10 40.6 0.3 1.6e-10 40.6 0.2 1.8 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EIW84108.1 - 1.5e-09 37.9 1.3 1.6e-09 37.8 0.3 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EIW84108.1 - 0.0056 17.1 0.6 0.0076 16.7 0.4 1.2 1 0 0 1 1 1 1 Complex1_LYR-like eIF-1a PF01176.14 EIW84109.1 - 8.6e-29 98.7 0.1 1.2e-28 98.2 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Ank_2 PF12796.2 EIW84110.1 - 9.4e-09 35.5 0.0 1.1e-07 32.0 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EIW84110.1 - 4.8e-05 22.9 0.0 0.57 10.1 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EIW84110.1 - 0.00014 22.2 0.0 0.036 14.5 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EIW84110.1 - 0.0015 18.7 0.0 2.2 8.6 0.0 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIW84110.1 - 0.0024 17.9 0.0 3.3 8.2 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Sugar_tr PF00083.19 EIW84111.1 - 3.1e-80 269.9 15.7 3.7e-58 197.2 1.3 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EIW84111.1 - 1.6e-16 59.9 19.0 1.9e-08 33.4 3.3 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Macro PF01661.16 EIW84112.1 - 1.2e-32 112.3 0.2 1.3e-30 105.7 0.1 2.2 1 1 0 1 1 1 1 Macro domain Pkinase PF00069.20 EIW84113.1 - 1.8e-63 214.1 0.0 2.3e-63 213.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW84113.1 - 7.4e-36 123.5 0.0 9.1e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW84113.1 - 1.1e-08 34.4 0.0 1.6e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW84113.1 - 0.00028 20.7 1.3 0.00037 20.2 0.2 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EIW84113.1 - 0.039 12.9 0.2 0.14 11.2 0.1 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EIW84113.1 - 0.056 12.2 0.0 0.094 11.4 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 EIW84113.1 - 0.074 12.3 0.1 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.6 EIW84113.1 - 0.087 11.6 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 NPR3 PF03666.8 EIW84116.1 - 9.8e-57 192.4 4.7 9.8e-57 192.4 3.3 2.5 2 1 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 SAD_SRA PF02182.12 EIW84117.1 - 1.1e-39 135.2 1.1 1.4e-39 134.8 0.8 1.0 1 0 0 1 1 1 1 SAD/SRA domain RtxA PF07634.6 EIW84117.1 - 0.41 11.0 2.7 14 6.2 0.1 3.0 3 0 0 3 3 3 0 RtxA repeat Fijivirus_P9-2 PF06837.6 EIW84118.1 - 0.027 13.5 2.6 0.05 12.7 1.8 1.4 1 0 0 1 1 1 0 Fijivirus P9-2 protein Mito_fiss_reg PF05308.6 EIW84119.1 - 3.1 7.0 9.7 5.2 6.3 6.8 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Acetyltransf_3 PF13302.1 EIW84121.1 - 1.9e-24 86.4 0.0 2.4e-24 86.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIW84121.1 - 4.2e-07 29.9 0.0 0.0011 18.8 0.0 2.2 1 1 1 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIW84121.1 - 0.05 13.3 0.0 0.76 9.5 0.0 2.2 2 0 0 2 2 2 0 FR47-like protein Acetyltransf_1 PF00583.19 EIW84121.1 - 0.1 12.6 0.0 1.9 8.5 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family DUF1748 PF08520.5 EIW84122.1 - 1.9e-25 88.2 0.0 2.1e-25 88.1 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Y_phosphatase3 PF13350.1 EIW84123.1 - 9.1e-47 159.3 0.0 1.2e-46 158.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EIW84123.1 - 1.2e-08 34.9 0.0 3.8e-08 33.3 0.0 1.9 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EIW84123.1 - 0.00021 20.7 0.0 0.00033 20.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EIW84123.1 - 0.00058 19.9 0.0 0.0012 18.8 0.0 1.5 1 1 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 EIW84123.1 - 0.0039 16.7 0.0 0.0075 15.8 0.0 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.8 EIW84123.1 - 0.015 14.6 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family Exo_endo_phos PF03372.18 EIW84124.1 - 1.1e-13 51.7 0.2 1.2e-09 38.4 0.0 2.3 2 0 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family Ribosomal_S10 PF00338.17 EIW84125.1 - 9.7e-31 105.4 0.5 1.1e-30 105.2 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e CW_binding_2 PF04122.7 EIW84125.1 - 0.11 12.7 0.1 0.19 11.9 0.1 1.3 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 DUF572 PF04502.8 EIW84126.1 - 8.7e-58 196.0 0.1 1.1e-57 195.7 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF1320 PF07030.7 EIW84126.1 - 0.023 14.4 0.0 0.096 12.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1320) SNARE_assoc PF09335.6 EIW84128.1 - 3.6e-14 53.0 2.7 3.6e-14 53.0 1.9 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein Colicin PF01024.14 EIW84128.1 - 0.89 9.1 3.4 0.36 10.3 0.4 1.6 2 0 0 2 2 2 0 Colicin pore forming domain Fungal_trans PF04082.13 EIW84129.1 - 2.8e-18 65.7 0.0 5.1e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW84129.1 - 9.1e-08 31.8 13.1 1.6e-07 31.1 9.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FCP1_C PF09309.5 EIW84129.1 - 0.38 10.0 6.6 0.91 8.7 4.6 1.7 1 0 0 1 1 1 0 FCP1, C-terminal cobW PF02492.14 EIW84130.1 - 1.6e-37 128.6 0.1 2.1e-37 128.2 0.1 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EIW84130.1 - 0.00093 18.8 0.0 0.0047 16.6 0.0 2.0 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.9 EIW84130.1 - 0.0028 17.3 0.0 0.0086 15.7 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Pox_A32 PF04665.7 EIW84130.1 - 0.052 12.8 0.1 0.26 10.5 0.0 1.9 2 0 0 2 2 2 0 Poxvirus A32 protein tRNA_anti-codon PF01336.20 EIW84130.1 - 0.1 12.4 0.0 0.25 11.1 0.0 1.7 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Frag1 PF10277.4 EIW84131.1 - 7.9e-37 126.8 4.9 7.9e-37 126.8 3.4 3.1 3 1 0 3 3 3 1 Frag1/DRAM/Sfk1 family Adaptin_N PF01602.15 EIW84132.1 - 8.5e-119 397.2 4.4 1.1e-118 396.9 3.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EIW84132.1 - 2.1e-10 40.7 1.5 0.0032 17.6 0.0 4.0 3 0 0 3 3 3 2 HEAT repeats HEAT PF02985.17 EIW84132.1 - 1e-06 28.3 4.0 0.36 11.0 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EIW84132.1 - 0.0005 20.4 2.3 13 6.4 0.0 5.1 3 1 1 4 4 4 2 HEAT-like repeat Cohesin_HEAT PF12765.2 EIW84132.1 - 0.024 14.6 5.1 0.22 11.5 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion HTH_36 PF13730.1 EIW84132.1 - 0.087 12.9 0.1 0.41 10.8 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain Cnd1 PF12717.2 EIW84132.1 - 0.2 11.4 3.5 1.9 8.2 0.0 3.4 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 CobT PF06213.7 EIW84132.1 - 7.6 5.5 18.4 13 4.8 12.8 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT COX6B PF02297.12 EIW84133.1 - 1.8e-20 72.7 5.3 2.1e-20 72.5 3.7 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb TetR_C_8 PF14278.1 EIW84133.1 - 0.015 15.6 0.1 0.021 15.1 0.1 1.2 1 0 0 1 1 1 0 Transcriptional regulator C-terminal region CHCH PF06747.8 EIW84133.1 - 0.016 15.1 1.7 0.041 13.8 1.1 1.8 1 1 0 1 1 1 0 CHCH domain UPF0203 PF05254.7 EIW84133.1 - 0.44 10.4 6.4 3.9 7.4 0.3 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Prp18 PF02840.10 EIW84134.1 - 1.4e-58 196.8 0.2 1.4e-58 196.8 0.1 1.9 3 0 0 3 3 3 1 Prp18 domain PRP4 PF08799.6 EIW84134.1 - 3.1e-11 42.3 4.3 6.7e-11 41.2 3.0 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like DnaJ PF00226.26 EIW84135.1 - 3.9e-27 93.7 0.4 1.2e-26 92.1 0.3 1.9 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 EIW84135.1 - 1.4e-09 37.7 0.9 1.4e-09 37.7 0.6 2.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIW84135.1 - 4.5e-09 36.1 1.5 1.2e-08 34.8 1.0 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EIW84135.1 - 1.3e-06 28.4 3.2 0.018 15.1 0.5 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EIW84135.1 - 0.002 18.3 4.8 0.48 10.8 0.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW84135.1 - 0.0026 17.9 2.9 0.22 11.9 0.5 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger RPT PF13446.1 EIW84135.1 - 0.016 14.5 0.7 0.075 12.4 0.0 2.3 3 0 0 3 3 3 0 A repeated domain in UCH-protein zf-C2H2_6 PF13912.1 EIW84135.1 - 0.035 13.9 0.1 0.035 13.9 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIW84135.1 - 0.043 14.1 3.0 0.36 11.2 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger double domain zf-Tim10_DDP PF02953.10 EIW84136.1 - 2.9e-21 74.5 1.3 3.4e-21 74.3 0.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Cytomega_TRL10 PF06084.6 EIW84136.1 - 0.0036 17.1 0.7 0.0039 16.9 0.5 1.1 1 0 0 1 1 1 1 Cytomegalovirus TRL10 protein NatB_MDM20 PF09797.4 EIW84136.1 - 0.088 11.4 0.3 0.087 11.5 0.2 1.0 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit CbiK PF06180.6 EIW84136.1 - 0.13 11.3 0.0 0.15 11.1 0.0 1.0 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) Homeobox PF00046.24 EIW84137.1 - 3.5e-19 68.1 2.6 6.3e-19 67.3 1.8 1.4 1 0 0 1 1 1 1 Homeobox domain U1snRNP70_N PF12220.3 EIW84138.1 - 5.7e-19 68.2 0.2 1e-18 67.4 0.2 1.4 1 0 0 1 1 1 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EIW84138.1 - 3.5e-15 55.3 0.0 6.2e-15 54.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW84138.1 - 4e-13 49.1 0.0 7.4e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW84138.1 - 1e-06 28.4 0.0 8.3e-06 25.5 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UbiA PF01040.13 EIW84139.1 - 3.7e-28 98.4 21.7 5.4e-28 97.9 15.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family NAPRTase PF04095.11 EIW84141.1 - 3.2e-55 187.0 0.1 4.7e-55 186.5 0.0 1.3 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Methyltransf_4 PF02390.12 EIW84142.1 - 5.7e-54 182.1 0.0 6.7e-54 181.9 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EIW84142.1 - 3e-07 31.0 0.0 4.8e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW84142.1 - 1.3e-05 25.1 0.0 2.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW84142.1 - 0.00018 21.8 0.0 0.00034 20.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW84142.1 - 0.0008 19.0 0.0 0.0014 18.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW84142.1 - 0.0038 17.6 0.0 0.061 13.8 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW84142.1 - 0.005 16.2 0.0 0.012 15.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.6 EIW84142.1 - 0.037 13.0 0.0 0.072 12.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_12 PF08242.7 EIW84142.1 - 0.079 13.4 0.0 0.57 10.6 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain PqqA PF08042.6 EIW84142.1 - 0.13 12.0 1.3 0.42 10.3 0.1 2.2 2 0 0 2 2 2 0 PqqA family Retrotrans_gag PF03732.12 EIW84147.1 - 0.019 15.0 0.1 0.23 11.5 0.0 2.2 2 0 0 2 2 2 0 Retrotransposon gag protein HrpB7 PF09486.5 EIW84147.1 - 0.19 11.6 3.5 0.33 10.8 2.4 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) zf-CCHC PF00098.18 EIW84147.1 - 2.3 8.3 7.4 0.61 10.1 2.3 2.2 2 1 0 2 2 2 0 Zinc knuckle Myc_N PF01056.13 EIW84149.1 - 0.077 12.1 0.1 0.083 12.0 0.1 1.0 1 0 0 1 1 1 0 Myc amino-terminal region UBN2_2 PF14227.1 EIW84154.1 - 9.2e-06 25.2 0.0 2.3e-05 23.9 0.0 1.6 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIW84154.1 - 2.5e-05 24.0 0.0 5.3e-05 22.9 0.0 1.5 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EIW84156.1 - 0.0064 16.0 0.0 0.01 15.4 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Pox_ser-thr_kin PF05445.6 EIW84158.1 - 0.11 11.3 0.2 0.15 10.8 0.1 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pneumo_M2 PF07380.6 EIW84160.1 - 0.1 12.5 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Pneumovirus M2 protein DUF1421 PF07223.6 EIW84160.1 - 1.6 8.4 25.2 2.8 7.6 17.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) Cerato-platanin PF07249.7 EIW84161.1 - 4.8e-08 33.0 1.0 1.4e-07 31.5 0.1 2.1 2 0 0 2 2 2 1 Cerato-platanin Methyltransf_23 PF13489.1 EIW84161.1 - 1e-05 25.2 0.1 2.5e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW84161.1 - 2.8e-05 24.6 0.1 5.8e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW84161.1 - 0.00011 21.7 0.1 0.00022 20.8 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Utp8 PF10395.4 EIW84161.1 - 0.00027 19.3 0.0 0.00037 18.9 0.0 1.1 1 0 0 1 1 1 1 Utp8 family Methyltransf_11 PF08241.7 EIW84161.1 - 0.00037 20.9 0.1 0.001 19.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EIW84161.1 - 0.00082 19.0 0.5 0.0016 18.1 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EIW84161.1 - 0.00099 18.2 0.0 0.0013 17.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EIW84161.1 - 0.0014 19.0 0.5 0.0028 18.1 0.1 1.7 2 0 0 2 2 1 1 Methyltransferase domain PrmA PF06325.8 EIW84161.1 - 0.0051 15.9 0.1 0.0073 15.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.6 EIW84161.1 - 0.0062 16.0 0.0 0.0087 15.5 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.9 EIW84161.1 - 0.0086 15.4 0.1 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 EIW84161.1 - 0.033 13.2 0.0 0.042 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MetW PF07021.7 EIW84161.1 - 0.055 12.8 0.1 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 EIW84161.1 - 0.1 12.6 0.3 0.21 11.6 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain DUF2065 PF09838.4 EIW84163.1 - 0.01 15.5 0.2 0.057 13.1 0.2 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2065) DASH_Spc34 PF08657.5 EIW84164.1 - 0.011 15.4 1.7 0.02 14.5 1.2 1.4 1 0 0 1 1 1 0 DASH complex subunit Spc34 Occludin_ELL PF07303.8 EIW84164.1 - 0.016 15.9 2.0 0.029 15.0 1.4 1.5 1 0 0 1 1 1 0 Occludin homology domain SPO22 PF08631.5 EIW84164.1 - 0.067 12.2 2.1 0.66 8.9 0.3 2.3 2 0 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like DED PF01335.16 EIW84164.1 - 0.14 12.3 1.1 0.34 11.0 0.6 1.8 1 1 0 1 1 1 0 Death effector domain DDE_3 PF13358.1 EIW84166.1 - 4.5e-06 26.4 0.1 6.6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease UBN2_2 PF14227.1 EIW84169.1 - 2e-07 30.6 0.0 4.1e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIW84169.1 - 2.1e-05 24.3 0.0 4.2e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_3 PF14244.1 EIW84169.1 - 0.023 14.2 2.0 0.064 12.8 1.4 1.7 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type MARVEL PF01284.18 EIW84172.1 - 1.2e-09 38.1 8.8 2e-09 37.4 6.1 1.4 1 0 0 1 1 1 1 Membrane-associating domain SH3_1 PF00018.23 EIW84173.1 - 2.8e-11 42.6 0.1 4e-11 42.1 0.1 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIW84173.1 - 8.2e-11 41.2 0.0 1.2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EIW84173.1 - 2.7e-10 39.6 0.1 4.6e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Mito_fiss_reg PF05308.6 EIW84173.1 - 4.9 6.4 6.9 0.34 10.2 1.0 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator Voldacs PF03517.8 EIW84174.1 - 5.5e-27 94.2 0.1 8.8e-27 93.5 0.1 1.2 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling PAS_7 PF12860.2 EIW84175.1 - 0.096 12.7 0.1 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 PAS fold COG2 PF06148.6 EIW84175.1 - 0.12 12.2 0.3 0.17 11.7 0.2 1.4 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 TMF_TATA_bd PF12325.3 EIW84175.1 - 0.27 10.9 3.0 0.19 11.4 1.1 1.6 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding YchF-GTPase_C PF06071.8 EIW84176.1 - 6e-36 122.0 0.4 1.4e-35 120.9 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EIW84176.1 - 2.7e-14 53.1 0.0 6.3e-14 51.9 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIW84176.1 - 2.3e-05 23.7 0.0 4e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_17 PF13207.1 EIW84176.1 - 0.11 13.3 0.0 0.29 11.9 0.0 2.1 1 1 0 1 1 1 0 AAA domain Adeno_E3 PF06040.6 EIW84177.1 - 0.049 13.5 1.4 0.1 12.5 0.1 1.9 2 0 0 2 2 2 0 Adenovirus E3 protein Med25_VWA PF11265.3 EIW84178.1 - 1.2e-07 31.0 0.0 2.3e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A Med13_C PF06333.7 EIW84178.1 - 0.0026 16.3 0.4 0.0026 16.3 0.3 2.1 1 1 1 2 2 2 1 Mediator complex subunit 13 C-terminal DUF4089 PF13318.1 EIW84178.1 - 0.12 12.7 0.4 0.33 11.2 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4089) PITH PF06201.8 EIW84179.1 - 1.6e-38 131.8 0.0 2e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain UBX PF00789.15 EIW84180.1 - 2e-11 43.7 0.2 3.5e-11 42.9 0.1 1.4 1 0 0 1 1 1 1 UBX domain DUF1490 PF07371.7 EIW84180.1 - 0.24 11.3 1.5 0.39 10.7 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1490) ThiF PF00899.16 EIW84181.1 - 6e-43 145.9 0.1 9.7e-43 145.2 0.1 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EIW84181.1 - 6e-26 89.8 0.1 1.8e-25 88.3 0.1 1.8 3 0 0 3 3 3 1 MoeZ/MoeB domain Rhodanese PF00581.15 EIW84181.1 - 1.2e-08 35.2 0.0 2.3e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 EIW84181.1 - 0.00018 21.6 0.1 0.00038 20.5 0.0 1.6 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 EIW84181.1 - 0.011 14.7 0.1 0.016 14.1 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EIW84181.1 - 0.015 15.5 0.0 0.026 14.7 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EIW84181.1 - 0.034 13.5 0.1 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Saccharop_dh PF03435.13 EIW84181.1 - 0.06 12.3 0.2 0.085 11.8 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 EIW84181.1 - 0.095 12.3 0.2 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EIW84181.1 - 0.11 11.5 0.1 0.15 11.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain APC10 PF03256.11 EIW84182.1 - 9.5e-47 159.0 0.0 1.2e-46 158.8 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.20 EIW84182.1 - 5.9e-06 26.1 0.0 1.4e-05 24.9 0.0 1.6 1 1 0 1 1 1 1 F5/8 type C domain PHD PF00628.24 EIW84183.1 - 1.1e-06 28.2 11.9 1.9e-06 27.4 8.3 1.5 1 0 0 1 1 1 1 PHD-finger Alba PF01918.16 EIW84184.1 - 0.0098 15.4 0.0 0.092 12.3 0.0 2.3 2 0 0 2 2 2 1 Alba P34-Arc PF04045.9 EIW84186.1 - 1.2e-105 352.1 0.7 1.5e-105 351.8 0.5 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc RRM_1 PF00076.17 EIW84187.1 - 1.2e-12 47.2 0.0 2.4e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW84187.1 - 1.1e-08 34.9 0.0 2.1e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW84187.1 - 0.14 12.0 0.3 0.26 11.1 0.0 1.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.17 EIW84188.1 - 2e-47 160.5 0.0 2.3e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW84188.1 - 2.6e-20 73.0 0.0 5.9e-20 71.9 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIW84188.1 - 4.3e-06 26.0 0.0 5.1e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIW84188.1 - 7.1e-05 22.3 0.0 0.00051 19.5 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIW84188.1 - 0.0043 16.9 0.0 0.0069 16.3 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Kdo_hydroxy PF11004.3 EIW84188.1 - 0.053 12.5 0.0 0.091 11.7 0.0 1.3 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase FeoB_N PF02421.13 EIW84188.1 - 0.063 12.5 0.0 0.17 11.1 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.13 EIW84188.1 - 0.07 12.1 0.0 0.18 10.7 0.0 1.6 2 0 0 2 2 2 0 Septin G-alpha PF00503.15 EIW84188.1 - 0.082 11.5 0.0 0.11 11.1 0.0 1.2 1 1 0 1 1 1 0 G-protein alpha subunit AAA_16 PF13191.1 EIW84188.1 - 0.11 12.4 0.0 0.37 10.7 0.0 1.8 2 1 0 2 2 2 0 AAA ATPase domain DEAD PF00270.24 EIW84189.1 - 2.5e-47 160.5 0.0 9.3e-46 155.3 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW84189.1 - 1.1e-10 41.1 0.0 2.7e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW84189.1 - 9.9e-06 25.4 0.0 4.7e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2443 PF10398.4 EIW84189.1 - 0.081 12.7 0.1 0.16 11.7 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Aminotran_3 PF00202.16 EIW84190.1 - 5.2e-43 147.1 0.0 2.8e-42 144.7 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-III AAA_26 PF13500.1 EIW84190.1 - 1.7e-28 99.6 0.0 3.3e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EIW84190.1 - 0.064 12.9 0.1 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SMP PF04927.7 EIW84190.1 - 0.089 12.7 0.0 0.43 10.5 0.0 2.1 2 0 0 2 2 2 0 Seed maturation protein CbiA PF01656.18 EIW84190.1 - 0.092 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF3166 PF11365.3 EIW84191.1 - 0.12 12.8 0.6 0.22 11.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) NUDIX PF00293.23 EIW84192.1 - 8.4e-17 61.0 0.0 1.3e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF1192 PF06698.6 EIW84193.1 - 0.026 14.3 1.6 0.13 12.1 1.1 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) PI3Ka PF00613.15 EIW84194.1 - 4.3e-55 185.7 0.1 6.6e-55 185.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EIW84194.1 - 1.8e-44 151.9 0.0 4.6e-43 147.3 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EIW84194.1 - 7.1e-41 139.3 0.0 1.4e-40 138.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 C2 PF00168.25 EIW84194.1 - 0.0015 18.3 0.0 0.0044 16.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain A1_Propeptide PF07966.7 EIW84194.1 - 0.076 12.8 0.2 12 5.8 0.2 3.0 2 0 0 2 2 2 0 A1 Propeptide IlvN PF07991.7 EIW84195.1 - 5.6e-46 155.9 0.0 1.1e-45 154.9 0.0 1.5 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EIW84195.1 - 6.6e-41 139.6 0.0 9.5e-41 139.1 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TauD PF02668.11 EIW84196.1 - 7.7e-39 133.9 0.0 1.1e-38 133.4 0.0 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF971 PF06155.7 EIW84196.1 - 0.00025 21.4 0.0 0.00065 20.0 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF971) CsiD PF08943.5 EIW84196.1 - 0.027 13.3 0.1 0.17 10.7 0.0 1.9 2 0 0 2 2 2 0 CsiD Aconitase PF00330.15 EIW84197.1 - 4.1e-74 249.7 1.1 2.6e-43 148.2 0.0 3.0 2 1 1 3 3 3 3 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EIW84197.1 - 7.5e-21 74.6 0.0 1.4e-20 73.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.8 EIW84197.1 - 0.0019 17.6 0.0 0.01 15.2 0.0 2.0 2 0 0 2 2 2 1 Aconitate hydratase 2 N-terminus Telomere_Sde2 PF13019.1 EIW84198.1 - 2e-50 170.6 0.0 2.5e-50 170.3 0.0 1.1 1 0 0 1 1 1 1 Telomere stability and silencing GTSE1_N PF15259.1 EIW84198.1 - 0.014 15.3 0.8 0.023 14.6 0.5 1.3 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 DUF1295 PF06966.7 EIW84199.1 - 9.5e-29 100.3 3.6 1.6e-27 96.3 2.5 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EIW84199.1 - 0.032 14.4 0.2 0.12 12.5 0.0 2.1 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Ras PF00071.17 EIW84200.1 - 1.2e-57 193.7 0.2 1.4e-57 193.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW84200.1 - 8.2e-20 71.4 0.0 1.2e-19 70.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW84200.1 - 2.4e-08 33.4 0.0 2.9e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIW84200.1 - 1.9e-06 27.4 0.1 3.8e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EIW84200.1 - 0.0025 17.1 0.1 0.0061 15.8 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.18 EIW84200.1 - 0.0083 16.0 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ser_hydrolase PF06821.8 EIW84200.1 - 0.13 11.8 0.0 0.18 11.3 0.0 1.1 1 0 0 1 1 1 0 Serine hydrolase ATP_bind_1 PF03029.12 EIW84200.1 - 0.14 11.6 1.9 1.3 8.4 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein CIA30 PF08547.7 EIW84201.1 - 1.2e-23 83.7 0.0 1.5e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) DUF3392 PF11872.3 EIW84202.1 - 0.041 13.8 0.3 0.041 13.8 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3392) IMS PF00817.15 EIW84203.1 - 2.3e-43 147.5 0.0 5.3e-43 146.3 0.0 1.6 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EIW84203.1 - 1.6e-10 40.9 0.0 1.5e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EIW84203.1 - 0.03 14.3 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif Pyr_redox_2 PF07992.9 EIW84204.1 - 2.9e-27 95.8 0.7 5.5e-27 94.9 0.5 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EIW84204.1 - 5.8e-18 64.2 0.2 1.5e-17 62.9 0.2 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EIW84204.1 - 3.6e-12 46.7 0.2 3.1e-05 24.1 0.0 3.2 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW84204.1 - 9.1e-10 38.8 4.1 5.4e-09 36.3 0.2 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 EIW84204.1 - 6.8e-08 32.7 0.0 2.1e-07 31.1 0.0 1.8 2 0 0 2 2 2 1 Reductase C-terminal Rieske_2 PF13806.1 EIW84204.1 - 9.7e-08 31.6 0.0 2.3e-07 30.5 0.0 1.7 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain K_oxygenase PF13434.1 EIW84204.1 - 0.0088 14.9 0.0 0.57 9.0 0.0 2.2 1 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_7 PF13241.1 EIW84204.1 - 0.014 15.6 0.2 0.1 12.8 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EIW84204.1 - 0.049 13.4 0.2 21 4.8 0.0 3.1 2 1 1 3 3 3 0 FAD-NAD(P)-binding Metallophos PF00149.23 EIW84205.1 - 8.5e-06 25.3 5.9 2.8e-05 23.5 4.1 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ISK_Channel PF02060.10 EIW84206.1 - 0.071 12.7 0.3 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 Slow voltage-gated potassium channel ABC_membrane PF00664.18 EIW84207.1 - 2e-67 227.5 32.1 5e-34 117.9 10.2 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIW84207.1 - 1.7e-50 170.9 0.0 1e-28 100.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIW84207.1 - 2.3e-08 34.3 0.1 0.038 13.9 0.0 4.7 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.14 EIW84207.1 - 1.1e-07 31.3 0.3 0.032 13.4 0.0 3.9 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EIW84207.1 - 1e-05 25.0 0.1 0.057 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EIW84207.1 - 4.3e-05 22.9 0.3 0.28 10.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EIW84207.1 - 4.3e-05 23.9 1.5 0.16 12.4 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EIW84207.1 - 0.00013 21.9 1.2 0.13 12.2 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_23 PF13476.1 EIW84207.1 - 0.00018 21.8 1.9 0.95 9.7 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_10 PF12846.2 EIW84207.1 - 0.00019 20.9 0.1 0.64 9.3 0.0 2.6 3 0 0 3 3 3 2 AAA-like domain AAA_17 PF13207.1 EIW84207.1 - 0.00034 21.4 0.0 0.73 10.6 0.0 3.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIW84207.1 - 0.00049 20.1 0.4 0.12 12.4 0.0 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EIW84207.1 - 0.00051 20.3 0.1 0.87 9.9 0.0 3.1 3 0 0 3 3 2 1 AAA domain ATP-synt_ab PF00006.20 EIW84207.1 - 0.0007 19.1 0.0 0.82 9.1 0.0 2.3 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain DUF258 PF03193.11 EIW84207.1 - 0.0014 17.8 0.4 0.7 9.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EIW84207.1 - 0.0027 16.8 2.5 1.2 8.1 0.1 2.4 2 0 0 2 2 2 2 Zeta toxin UPF0079 PF02367.12 EIW84207.1 - 0.0037 16.8 0.8 0.041 13.5 0.1 2.6 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 EIW84207.1 - 0.0056 16.1 0.4 0.95 8.9 0.0 2.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family Dynamin_N PF00350.18 EIW84207.1 - 0.007 16.2 3.0 1.7 8.4 0.1 3.0 3 0 0 3 3 3 1 Dynamin family TrwB_AAD_bind PF10412.4 EIW84207.1 - 0.011 14.4 3.2 0.47 9.0 0.1 2.4 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain MobB PF03205.9 EIW84207.1 - 0.02 14.5 2.2 0.6 9.8 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EIW84207.1 - 0.034 13.6 2.7 20 4.6 0.1 3.3 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EIW84207.1 - 0.041 14.0 4.1 3 8.0 0.1 3.4 2 1 0 2 2 2 0 AAA domain NACHT PF05729.7 EIW84207.1 - 0.046 13.3 2.8 0.082 12.5 0.1 2.6 2 1 1 3 3 2 0 NACHT domain ArgK PF03308.11 EIW84207.1 - 0.046 12.4 0.5 3.7 6.2 0.1 2.4 2 0 0 2 2 2 0 ArgK protein T2SE PF00437.15 EIW84207.1 - 0.067 12.0 1.5 9.6 5.0 0.0 2.9 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_30 PF13604.1 EIW84207.1 - 0.089 12.3 4.2 3.4 7.1 0.1 3.2 3 0 0 3 3 3 0 AAA domain cobW PF02492.14 EIW84207.1 - 0.12 11.8 2.6 0.24 10.8 0.2 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EIW84207.1 - 0.17 11.7 2.1 5.2 6.9 0.2 3.1 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 EIW84207.1 - 0.19 11.8 1.2 20 5.4 0.0 3.3 3 0 0 3 3 3 0 RNA helicase AAA_13 PF13166.1 EIW84207.1 - 0.24 9.8 0.0 0.46 8.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EIW84207.1 - 0.24 10.9 1.5 1.8 8.0 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 EIW84207.1 - 0.28 10.0 2.0 13 4.5 0.3 2.4 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.1 EIW84207.1 - 0.57 9.1 0.0 12 4.7 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain NTPase_1 PF03266.10 EIW84207.1 - 2.8 7.6 5.0 4.9 6.8 0.3 2.7 3 0 0 3 3 2 0 NTPase DUF87 PF01935.12 EIW84207.1 - 5.6 6.7 8.5 0.79 9.4 0.1 2.6 3 0 0 3 3 2 0 Domain of unknown function DUF87 DEAD PF00270.24 EIW84208.1 - 2.1e-37 128.2 0.0 5.4e-37 126.8 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW84208.1 - 1.3e-20 73.0 0.0 2.5e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW84208.1 - 6.2e-10 39.2 0.0 1.3e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EIW84208.1 - 0.0085 15.8 0.1 0.025 14.3 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EIW84208.1 - 0.032 14.3 0.1 3.8 7.6 0.0 2.7 3 0 0 3 3 3 0 AAA domain Flavi_DEAD PF07652.9 EIW84208.1 - 0.13 11.9 0.2 0.26 11.0 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain p450 PF00067.17 EIW84209.1 - 4.4e-67 226.5 0.0 1.9e-66 224.4 0.0 1.8 1 1 0 1 1 1 1 Cytochrome P450 bZIP_C PF12498.3 EIW84210.1 - 9.6 7.4 10.4 0.67 11.1 0.4 2.9 3 1 0 3 3 3 0 Basic leucine-zipper C terminal MOZ_SAS PF01853.13 EIW84211.1 - 4.5e-71 237.9 0.1 6.2e-71 237.5 0.1 1.1 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 EIW84212.1 - 1.3e-06 27.9 10.2 1.4e-06 27.8 3.3 2.0 1 1 1 2 2 2 1 PHD-finger XPA_N PF01286.13 EIW84212.1 - 0.064 12.9 6.0 0.17 11.6 0.8 2.2 2 0 0 2 2 2 0 XPA protein N-terminal Fer4_2 PF12797.2 EIW84212.1 - 0.098 12.6 1.9 0.098 12.6 1.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain C1_1 PF00130.17 EIW84212.1 - 0.15 11.7 0.3 0.15 11.7 0.2 2.7 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EIW84212.1 - 0.31 10.7 0.2 0.31 10.7 0.1 2.5 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 Fer4_10 PF13237.1 EIW84212.1 - 0.35 10.6 8.9 1.3 8.9 6.2 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain zf-trcl PF13451.1 EIW84212.1 - 0.57 9.8 8.2 6.3 6.5 0.2 2.9 2 1 0 2 2 2 0 Probable zinc-binding domain DUF116 PF01976.12 EIW84212.1 - 4.2 6.8 7.5 0.23 10.9 1.6 1.5 2 0 0 2 2 2 0 Protein of unknown function DUF116 Pkinase PF00069.20 EIW84213.1 - 9e-56 188.8 0.0 1.2e-55 188.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW84213.1 - 4.7e-19 68.4 0.0 1e-18 67.3 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EIW84213.1 - 0.071 12.4 0.1 0.23 10.7 0.0 1.8 1 1 1 2 2 2 0 RIO1 family TRAP_alpha PF03896.11 EIW84214.1 - 0.00014 20.9 0.0 0.00018 20.6 0.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit Urease_beta PF00699.15 EIW84214.1 - 0.0067 16.2 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Urease beta subunit ECH PF00378.15 EIW84215.1 - 5.5e-21 74.7 0.0 7.3e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EIW84215.1 - 0.058 13.1 0.2 0.74 9.5 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 WD40 PF00400.27 EIW84216.1 - 1.8e-25 87.8 2.2 1.9e-06 27.5 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat YodA PF09223.6 EIW84216.1 - 0.03 13.9 0.3 0.046 13.3 0.2 1.2 1 0 0 1 1 1 0 YodA lipocalin-like domain Nucleoporin_N PF08801.6 EIW84216.1 - 0.04 12.6 0.0 0.16 10.6 0.0 1.9 1 1 1 2 2 2 0 Nup133 N terminal like Nup160 PF11715.3 EIW84216.1 - 0.11 10.6 0.1 0.56 8.2 0.0 1.9 1 1 0 1 1 1 0 Nucleoporin Nup120/160 RNA_pol_Rpb5_C PF01191.14 EIW84217.1 - 6.9e-35 118.4 0.2 1.5e-34 117.4 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EIW84217.1 - 4.8e-30 103.8 0.2 8.1e-30 103.1 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.7 EIW84217.1 - 0.011 15.4 0.1 0.02 14.7 0.0 1.4 1 1 0 1 1 1 0 Restriction endonuclease Terpene_synth_C PF03936.11 EIW84218.1 - 3.3e-11 42.9 0.0 4.5e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Acyl-CoA_dh_C PF12806.2 EIW84218.1 - 0.14 12.0 0.1 0.39 10.5 0.1 1.7 2 0 0 2 2 2 0 Acetyl-CoA dehydrogenase C-terminal like Cys_Met_Meta_PP PF01053.15 EIW84219.1 - 8.6e-126 419.3 0.0 1.1e-125 418.9 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme GHMP_kinases_N PF00288.21 EIW84219.1 - 2.1e-17 62.8 0.4 2.1e-16 59.7 0.1 2.9 3 1 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EIW84219.1 - 3.4e-05 23.9 2.6 0.00012 22.2 0.1 2.6 1 1 1 2 2 2 1 GHMP kinases C terminal DegT_DnrJ_EryC1 PF01041.12 EIW84219.1 - 0.00024 20.2 0.0 0.00058 19.0 0.0 1.6 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EIW84219.1 - 0.0012 18.1 0.2 0.0027 16.8 0.1 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase GalKase_gal_bdg PF10509.4 EIW84219.1 - 0.0013 18.0 0.0 0.0026 16.9 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Met_gamma_lyase PF06838.6 EIW84219.1 - 0.003 15.9 0.0 0.011 14.0 0.0 1.8 1 1 0 1 1 1 1 Methionine gamma-lyase SfsA PF03749.8 EIW84220.1 - 0.057 12.8 0.0 0.072 12.5 0.0 1.2 1 0 0 1 1 1 0 Sugar fermentation stimulation protein HMGL-like PF00682.14 EIW84221.1 - 1.3e-69 234.4 0.8 1.8e-69 234.0 0.2 1.5 2 0 0 2 2 2 1 HMGL-like Response_reg PF00072.19 EIW84222.1 - 4.3e-18 65.3 0.0 1.1e-17 63.9 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 EIW84222.1 - 8.4e-17 60.8 0.1 1.8e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EIW84222.1 - 4.1e-15 55.5 0.0 1.8e-14 53.4 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain CTP_transf_1 PF01148.15 EIW84223.1 - 2.3e-08 34.0 7.3 2.3e-08 34.0 5.1 3.7 2 2 2 4 4 4 1 Cytidylyltransferase family UDG PF03167.14 EIW84224.1 - 3e-21 75.4 0.0 2.1e-11 43.4 0.0 2.2 2 0 0 2 2 2 2 Uracil DNA glycosylase superfamily bZIP_1 PF00170.16 EIW84225.1 - 0.00039 20.2 3.2 0.00066 19.5 2.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIW84225.1 - 0.006 16.3 1.6 0.012 15.3 1.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Shugoshin_N PF07558.6 EIW84225.1 - 0.017 14.8 0.6 0.026 14.2 0.4 1.3 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region WD40_alt PF14077.1 EIW84225.1 - 0.071 12.7 0.3 0.13 11.9 0.2 1.3 1 0 0 1 1 1 0 Alternative WD40 repeat motif Helicase_C_3 PF13625.1 EIW84226.1 - 5.7e-28 97.2 0.1 2.2e-27 95.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW84226.1 - 3.6e-14 53.0 0.1 1e-13 51.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EIW84226.1 - 2.5e-12 46.1 0.1 4.2e-12 45.4 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW84226.1 - 4.8e-10 39.1 0.0 1.2e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_34 PF13872.1 EIW84226.1 - 0.051 12.3 0.1 0.093 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 zf-CCHC PF00098.18 EIW84227.1 - 4.3e-12 45.3 7.1 9.6e-06 25.2 0.1 2.5 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.1 EIW84227.1 - 3e-07 30.0 2.9 0.0017 18.0 1.0 2.4 1 1 1 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EIW84227.1 - 6.9e-05 22.4 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.1 EIW84227.1 - 0.00014 21.4 5.4 0.16 11.6 0.2 2.7 2 0 0 2 2 2 2 Zinc knuckle KH_3 PF13014.1 EIW84227.1 - 0.00017 21.1 0.0 0.00038 20.0 0.0 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_4 PF14392.1 EIW84227.1 - 0.00031 20.3 6.3 0.16 11.6 0.3 2.3 2 0 0 2 2 2 2 Zinc knuckle DnaJ_CXXCXGXG PF00684.14 EIW84227.1 - 0.02 14.9 4.5 0.056 13.4 3.1 1.7 1 0 0 1 1 1 0 DnaJ central domain zf-CCHC_2 PF13696.1 EIW84227.1 - 0.38 10.2 4.5 0.67 9.4 0.0 2.7 1 1 1 2 2 2 0 Zinc knuckle Nol1_Nop2_Fmu PF01189.12 EIW84228.1 - 1.2e-21 77.3 0.0 2.1e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 NOL1/NOP2/sun family Nucleocap_ssRNA PF11128.3 EIW84228.1 - 0.053 12.9 0.1 0.78 9.1 0.0 2.3 2 0 0 2 2 2 0 Plant viral coat protein nucleocapsid Fibrillarin PF01269.12 EIW84228.1 - 0.064 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin CTDII PF01556.13 EIW84229.1 - 7.5e-22 77.0 1.3 1.3e-20 73.0 0.0 2.7 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ PF00226.26 EIW84229.1 - 1.4e-14 53.5 0.5 5.8e-14 51.5 0.3 2.0 1 1 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EIW84229.1 - 4.9e-11 42.5 19.0 7.9e-11 41.8 13.2 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EIW84229.1 - 0.0029 17.2 7.3 0.1 12.2 1.3 2.2 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family Cytochrom_c3_2 PF14537.1 EIW84229.1 - 0.15 12.4 8.1 0.26 11.6 5.6 1.4 1 0 0 1 1 1 0 Cytochrome c3 Antiterm PF03589.8 EIW84229.1 - 2.1 8.4 6.0 9.4 6.3 4.1 2.0 1 1 0 1 1 1 0 Antitermination protein ThuA PF06283.6 EIW84230.1 - 2.5e-31 109.1 0.0 2.7e-31 108.9 0.0 1.0 1 0 0 1 1 1 1 Trehalose utilisation ABC_membrane PF00664.18 EIW84231.1 - 2.5e-59 200.9 23.4 7.1e-31 107.6 4.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIW84231.1 - 6.3e-51 172.2 0.0 1.5e-29 103.0 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EIW84231.1 - 6.4e-08 32.0 0.0 0.0031 16.7 0.0 3.8 2 2 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIW84231.1 - 6.7e-07 29.5 1.8 0.62 9.9 0.0 4.3 3 1 1 4 4 4 2 AAA domain AAA_25 PF13481.1 EIW84231.1 - 4.9e-05 22.8 0.2 0.051 12.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EIW84231.1 - 7.4e-05 22.8 0.6 0.047 13.6 0.0 2.9 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EIW84231.1 - 0.00013 21.4 1.3 0.32 10.5 0.2 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EIW84231.1 - 0.00029 21.6 0.0 0.87 10.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EIW84231.1 - 0.00077 18.6 3.3 0.13 11.4 0.4 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EIW84231.1 - 0.0017 18.7 3.5 0.29 11.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 EIW84231.1 - 0.002 18.0 0.9 0.23 11.4 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.1 EIW84231.1 - 0.0029 17.5 0.3 0.015 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIW84231.1 - 0.0084 15.8 0.4 0.068 12.9 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain ATP-synt_ab PF00006.20 EIW84231.1 - 0.0098 15.4 0.2 0.29 10.5 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Miro PF08477.8 EIW84231.1 - 0.013 16.0 1.2 0.77 10.2 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_22 PF13401.1 EIW84231.1 - 0.014 15.5 1.0 4.2 7.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain TrwB_AAD_bind PF10412.4 EIW84231.1 - 0.014 14.0 1.4 0.5 8.9 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain UPF0079 PF02367.12 EIW84231.1 - 0.015 14.9 1.7 0.033 13.8 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EIW84231.1 - 0.016 15.4 0.8 1.8 8.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EIW84231.1 - 0.024 14.1 1.9 6.7 6.2 0.0 2.8 3 0 0 3 3 3 0 AAA domain ArgK PF03308.11 EIW84231.1 - 0.038 12.7 1.6 2.9 6.5 0.1 2.6 2 0 0 2 2 2 0 ArgK protein AAA_13 PF13166.1 EIW84231.1 - 0.039 12.4 0.0 0.064 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EIW84231.1 - 0.05 13.4 0.9 6.6 6.5 0.1 2.7 2 0 0 2 2 2 0 Dynamin family MobB PF03205.9 EIW84231.1 - 0.056 13.1 1.2 4.4 7.0 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EIW84231.1 - 0.057 12.3 2.0 6.1 5.6 0.1 3.1 3 0 0 3 3 3 0 Type II/IV secretion system protein NTPase_1 PF03266.10 EIW84231.1 - 0.064 12.9 4.5 3.7 7.2 0.2 2.8 3 0 0 3 3 2 0 NTPase Zeta_toxin PF06414.7 EIW84231.1 - 0.11 11.5 0.8 13 4.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Activator_LAG-3 PF11498.3 EIW84231.1 - 0.15 10.7 0.7 0.24 10.1 0.5 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 NACHT PF05729.7 EIW84231.1 - 0.19 11.3 1.0 0.42 10.2 0.2 1.9 2 0 0 2 2 2 0 NACHT domain DUF853 PF05872.7 EIW84231.1 - 0.52 8.6 3.1 6.1 5.0 0.1 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) cobW PF02492.14 EIW84231.1 - 0.63 9.4 2.8 0.87 9.0 0.3 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 EIW84231.1 - 2.6 8.2 6.5 7 6.8 0.1 3.9 5 0 0 5 5 4 0 ATPase family associated with various cellular activities (AAA) C2 PF00168.25 EIW84232.1 - 7.3e-13 48.1 0.1 1.2e-12 47.4 0.1 1.4 1 0 0 1 1 1 1 C2 domain F_actin_cap_B PF01115.12 EIW84233.1 - 2.3e-101 338.0 0.0 3.1e-101 337.6 0.0 1.2 1 0 0 1 1 1 1 F-actin capping protein, beta subunit G-alpha PF00503.15 EIW84234.1 - 1.2e-136 455.5 0.0 1.4e-136 455.2 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIW84234.1 - 1e-12 47.6 0.1 2.2e-09 36.8 0.0 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Ras PF00071.17 EIW84234.1 - 0.00021 20.7 0.0 0.023 14.0 0.0 2.4 2 0 0 2 2 2 2 Ras family AAA_29 PF13555.1 EIW84234.1 - 0.024 14.1 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Gtr1_RagA PF04670.7 EIW84234.1 - 0.039 13.0 0.1 1.3 8.1 0.0 2.5 2 1 0 2 2 2 0 Gtr1/RagA G protein conserved region DUF3567 PF12091.3 EIW84234.1 - 0.088 12.7 0.0 1.9 8.5 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3567) Methyltransf_23 PF13489.1 EIW84235.1 - 2.5e-06 27.2 0.0 4.6e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW84235.1 - 0.00048 20.4 0.0 0.001 19.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW84235.1 - 0.0017 18.7 0.0 0.0043 17.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW84235.1 - 0.014 15.9 0.0 0.042 14.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 EIW84235.1 - 0.018 14.5 0.1 0.069 12.7 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EIW84235.1 - 0.095 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW ATP_synt_H PF05493.8 EIW84236.1 - 3.9e-20 71.6 4.8 4.4e-20 71.5 3.3 1.1 1 0 0 1 1 1 1 ATP synthase subunit H ARL6IP6 PF15062.1 EIW84236.1 - 0.0039 17.0 2.0 0.9 9.4 0.0 2.1 2 0 0 2 2 2 2 Haemopoietic lineage transmembrane helix ABC2_membrane_2 PF12679.2 EIW84236.1 - 0.049 12.4 4.5 0.055 12.3 3.1 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein COX7a PF02238.10 EIW84236.1 - 0.053 13.2 0.1 0.075 12.7 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIa MgtE PF01769.11 EIW84236.1 - 0.055 13.7 2.1 0.06 13.6 1.5 1.0 1 0 0 1 1 1 0 Divalent cation transporter DUF4131 PF13567.1 EIW84236.1 - 0.14 11.5 3.0 0.14 11.5 2.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) 7TMR-DISM_7TM PF07695.6 EIW84236.1 - 0.54 9.9 4.7 0.61 9.7 3.3 1.0 1 0 0 1 1 1 0 7TM diverse intracellular signalling p450 PF00067.17 EIW84237.1 - 1e-78 264.9 0.0 1.3e-78 264.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RNB PF00773.14 EIW84238.1 - 1.6e-46 159.0 0.0 2.7e-46 158.3 0.0 1.4 1 0 0 1 1 1 1 RNB domain Pkinase PF00069.20 EIW84239.1 - 5.1e-45 153.6 0.0 4.2e-25 88.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW84239.1 - 4.4e-22 78.3 0.0 3.8e-11 42.5 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIW84239.1 - 4.7e-07 29.0 0.0 0.00019 20.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EIW84239.1 - 2.3e-06 27.4 0.2 2e-05 24.4 0.1 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Vps51 PF08700.6 EIW84241.1 - 5.3e-24 83.8 1.3 6.8e-24 83.5 0.9 1.2 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.7 EIW84241.1 - 0.00011 20.8 0.9 0.00014 20.4 0.6 1.1 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.4 EIW84241.1 - 0.0054 16.6 1.1 0.0079 16.1 0.8 1.2 1 0 0 1 1 1 1 Golgi transport complex subunit 5 FlgN PF05130.7 EIW84241.1 - 0.0072 16.5 1.7 0.0092 16.2 1.1 1.1 1 0 0 1 1 1 1 FlgN protein DUF1440 PF07274.7 EIW84244.1 - 0.0026 17.7 0.6 0.0026 17.7 0.4 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1440) Thaumatin PF00314.12 EIW84245.1 - 2.5e-13 50.0 11.2 3.1e-13 49.7 7.7 1.2 1 0 0 1 1 1 1 Thaumatin family Methyltransf_28 PF02636.12 EIW84246.1 - 1e-58 198.7 0.0 1.3e-58 198.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase eIF-6 PF01912.13 EIW84247.1 - 8.9e-86 286.0 0.5 1.3e-85 285.4 0.3 1.3 1 0 0 1 1 1 1 eIF-6 family eIF3_subunit PF08597.5 EIW84248.1 - 2.2e-43 148.6 21.7 2.4e-43 148.4 15.0 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit U1snRNP70_N PF12220.3 EIW84248.1 - 5.5 7.3 8.3 1.7 9.0 2.2 2.4 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal WD40 PF00400.27 EIW84249.1 - 9.4e-23 79.2 13.4 1.6e-07 30.9 0.1 6.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EIW84249.1 - 0.0027 15.8 0.2 0.39 8.7 0.1 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 PAT1 PF09770.4 EIW84250.1 - 9.3 4.3 14.0 10 4.1 9.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lipase_3 PF01764.20 EIW84252.1 - 2.5e-07 30.3 0.0 5.5e-07 29.2 0.0 1.6 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EIW84252.1 - 0.0055 16.4 0.0 0.015 15.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 EIW84252.1 - 0.04 13.6 0.2 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) Virul_fac_BrkB PF03631.10 EIW84253.1 - 0.014 14.7 3.4 0.016 14.5 2.4 1.2 1 0 0 1 1 1 0 Virulence factor BrkB GTF2I PF02946.9 EIW84254.1 - 0.014 15.2 0.0 0.03 14.1 0.0 1.5 1 0 0 1 1 1 0 GTF2I-like repeat Apc3 PF12895.2 EIW84255.1 - 0.17 12.0 2.4 0.47 10.6 0.2 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 BIV_Env PF05858.7 EIW84256.1 - 0.0062 14.5 0.2 0.009 14.0 0.1 1.2 1 0 0 1 1 1 1 Bovine immunodeficiency virus surface protein (SU) Trep_Strep PF09605.5 EIW84256.1 - 0.019 14.6 1.0 0.019 14.6 0.7 2.6 3 1 0 3 3 3 0 Hypothetical bacterial integral membrane protein (Trep_Strep) BphX PF06139.7 EIW84256.1 - 0.19 11.3 7.3 0.061 12.9 2.9 1.7 2 0 0 2 2 2 0 BphX-like DUF308 PF03729.8 EIW84256.1 - 1.2 9.2 7.8 0.097 12.6 1.4 2.1 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) COesterase PF00135.23 EIW84257.1 - 3.4e-94 316.4 0.3 4.4e-94 316.1 0.2 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW84257.1 - 2.3e-08 33.8 0.5 5.2e-08 32.7 0.3 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EIW84257.1 - 0.0046 16.2 0.5 0.011 14.9 0.1 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family FTZ PF03867.9 EIW84257.1 - 0.0083 15.4 0.1 0.02 14.1 0.0 1.6 1 0 0 1 1 1 1 Fushi tarazu (FTZ), N-terminal region Abhydrolase_5 PF12695.2 EIW84257.1 - 0.023 14.4 0.2 0.04 13.6 0.2 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family MDH PF02315.11 EIW84259.1 - 0.098 12.5 0.4 0.23 11.4 0.3 1.6 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit Pneumo_ncap PF03246.8 EIW84259.1 - 0.17 10.3 0.0 0.24 9.8 0.0 1.1 1 0 0 1 1 1 0 Pneumovirus nucleocapsid protein NADH5_C PF06455.6 EIW84260.1 - 0.26 10.6 2.0 2.8 7.2 0.0 2.1 2 0 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus Sdh_cyt PF01127.17 EIW84260.1 - 1 9.2 5.2 0.2 11.5 0.3 2.0 1 1 1 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Yip1 PF04893.12 EIW84260.1 - 1.1 8.7 11.2 1.8 8.0 7.7 1.4 1 1 0 1 1 1 0 Yip1 domain RhoGEF PF00621.15 EIW84261.1 - 9.5e-34 116.8 0.1 1.4e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 RhoGEF domain CNH PF00780.17 EIW84261.1 - 1.1e-28 100.4 0.0 1.6e-28 99.9 0.0 1.2 1 0 0 1 1 1 1 CNH domain PH_5 PF15405.1 EIW84261.1 - 9.1e-08 32.1 0.0 2.3e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EIW84261.1 - 0.00013 22.1 0.0 0.0003 20.9 0.0 1.6 1 0 0 1 1 1 1 PH domain DUF2247 PF10004.4 EIW84265.1 - 0.087 12.5 0.2 0.14 11.8 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2247) RNase_HII PF01351.13 EIW84266.1 - 1.4e-48 165.1 0.0 2e-48 164.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII ADH_zinc_N PF00107.21 EIW84267.1 - 9.1e-19 67.3 0.2 1.8e-18 66.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW84267.1 - 1e-08 36.1 0.1 2.5e-08 34.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 EIW84267.1 - 0.0064 16.0 0.1 0.01 15.4 0.1 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Abhydrolase_7 PF12715.2 EIW84267.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Abhydrolase family DivIC PF04977.10 EIW84268.1 - 0.0019 17.6 2.4 0.0019 17.6 1.7 3.5 2 2 1 3 3 3 1 Septum formation initiator DUF2458 PF10454.4 EIW84268.1 - 0.071 13.0 6.4 0.1 12.4 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) IFT57 PF10498.4 EIW84268.1 - 0.1 11.2 6.1 0.013 14.2 0.6 1.8 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 FlxA PF14282.1 EIW84268.1 - 0.16 11.9 4.9 1.2 9.0 0.4 2.3 2 0 0 2 2 2 0 FlxA-like protein Rabaptin PF03528.10 EIW84268.1 - 0.57 10.1 15.3 3 7.8 5.9 2.9 1 1 1 2 2 2 0 Rabaptin Snapin_Pallidin PF14712.1 EIW84268.1 - 0.88 9.9 6.9 1.9 8.8 0.2 2.5 2 0 0 2 2 2 0 Snapin/Pallidin TSC22 PF01166.13 EIW84268.1 - 1.2 9.1 7.9 0.57 10.1 0.2 2.9 3 0 0 3 3 3 0 TSC-22/dip/bun family Fib_alpha PF08702.5 EIW84268.1 - 1.5 8.9 6.6 0.71 9.9 0.3 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.3 EIW84268.1 - 1.9 8.3 13.2 0.096 12.5 0.9 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Prefoldin PF02996.12 EIW84268.1 - 2 8.1 6.5 15 5.2 0.3 2.9 3 1 0 3 3 3 0 Prefoldin subunit DUF972 PF06156.8 EIW84268.1 - 4 7.8 8.9 0.94 9.8 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4510 PF14971.1 EIW84268.1 - 4.5 7.4 7.6 13 5.9 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) TPR_MLP1_2 PF07926.7 EIW84268.1 - 5.5 6.7 12.3 1.2e+02 2.4 8.5 2.7 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein KLRAQ PF10205.4 EIW84268.1 - 5.8 6.9 11.8 0.59 10.2 0.2 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein DUF1640 PF07798.6 EIW84268.1 - 7.8 6.5 9.5 36 4.3 6.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF1319 PF07028.6 EIW84268.1 - 8 6.6 10.8 0.63 10.2 0.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) Ead_Ea22 PF13935.1 EIW84268.1 - 8.1 6.7 7.8 43 4.4 5.4 2.0 1 1 0 1 1 1 0 Ead/Ea22-like protein Alpha-amylase PF00128.19 EIW84269.1 - 6.8e-26 91.4 0.0 2e-25 89.8 0.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EIW84269.1 - 9.4e-05 20.3 0.0 0.56 7.9 0.0 3.6 3 1 0 3 3 3 3 Glycosyl hydrolase family 70 Sugar_tr PF00083.19 EIW84270.1 - 1.2e-70 238.3 26.5 1.5e-70 238.0 18.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW84270.1 - 5.2e-26 91.1 34.5 3.9e-17 61.9 12.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UDG PF03167.14 EIW84271.1 - 0.072 12.5 0.2 0.079 12.4 0.2 1.1 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily BNR_2 PF13088.1 EIW84272.1 - 1.6e-16 60.4 2.3 9.4e-06 25.1 0.0 3.1 1 1 1 3 3 3 3 BNR repeat-like domain BNR PF02012.15 EIW84272.1 - 2e-07 29.7 28.5 0.081 12.7 0.3 5.8 5 0 0 5 5 5 5 BNR/Asp-box repeat BNR_3 PF13859.1 EIW84272.1 - 0.01 14.9 0.7 2.2 7.2 0.2 2.9 1 1 3 4 4 4 0 BNR repeat-like domain Exo_endo_phos PF03372.18 EIW84273.1 - 9.6e-12 45.3 0.0 1.7e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Thioredoxin PF00085.15 EIW84274.1 - 4.6e-59 196.5 0.0 2.9e-29 100.8 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EIW84274.1 - 4.4e-24 84.9 1.1 9e-24 83.9 0.1 2.0 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EIW84274.1 - 2.3e-20 72.8 0.3 3.1e-10 40.2 0.0 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EIW84274.1 - 6.3e-14 51.7 0.1 6.1e-07 29.3 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EIW84274.1 - 3.7e-13 49.3 0.1 5.5e-05 23.2 0.0 3.5 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_6 PF13848.1 EIW84274.1 - 9.5e-10 38.5 0.1 0.00036 20.3 0.0 3.9 3 1 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.16 EIW84274.1 - 9.7e-09 34.9 0.1 0.0014 18.3 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 EIW84274.1 - 1.9e-07 30.7 0.4 0.0072 15.8 0.1 2.3 2 0 0 2 2 2 2 Redoxin Thioredoxin_3 PF13192.1 EIW84274.1 - 5.3e-06 26.1 0.1 0.0063 16.2 0.1 2.7 2 0 0 2 2 2 2 Thioredoxin domain Thioredoxin_9 PF14595.1 EIW84274.1 - 6.3e-05 22.5 1.1 0.065 12.8 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_4 PF13462.1 EIW84274.1 - 0.00059 19.8 0.4 0.44 10.5 0.2 2.7 2 1 0 2 2 2 2 Thioredoxin Glutaredoxin PF00462.19 EIW84274.1 - 0.00071 19.5 1.4 0.022 14.7 0.0 2.9 2 1 0 2 2 2 1 Glutaredoxin TraF PF13728.1 EIW84274.1 - 0.00082 18.9 0.0 1.1 8.7 0.0 2.3 2 0 0 2 2 2 2 F plasmid transfer operon protein HyaE PF07449.6 EIW84274.1 - 0.0041 16.9 0.0 0.27 11.1 0.0 2.5 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE WD40 PF00400.27 EIW84275.1 - 2.8e-53 175.9 14.5 4.9e-11 42.0 0.0 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW84275.1 - 0.00043 19.8 2.0 0.13 11.7 0.0 3.2 1 1 1 2 2 2 2 PQQ-like domain Glyoxal_oxid_N PF07250.6 EIW84275.1 - 0.05 12.6 0.1 0.11 11.5 0.0 1.6 1 0 0 1 1 1 0 Glyoxal oxidase N-terminus Nup160 PF11715.3 EIW84275.1 - 0.21 9.6 0.5 1.7 6.6 0.0 2.6 1 1 1 3 3 3 0 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EIW84275.1 - 1.8 8.9 13.4 8.8 6.7 0.0 5.4 6 0 0 6 6 6 0 PQQ-like domain MIP PF00230.15 EIW84276.1 - 5.2e-28 98.0 10.9 7.5e-28 97.5 7.6 1.2 1 0 0 1 1 1 1 Major intrinsic protein LsmAD PF06741.8 EIW84277.1 - 7.2e-25 86.8 0.3 1.7e-24 85.7 0.2 1.7 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.1 EIW84277.1 - 2.6e-06 27.2 0.0 6.2e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Ataxin 2 SM domain Pkinase PF00069.20 EIW84278.1 - 1.1e-16 60.7 0.0 1.9e-16 60.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Mad3_BUB1_I PF08311.7 EIW84278.1 - 4.7e-16 58.7 0.0 7.9e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase_Tyr PF07714.12 EIW84278.1 - 7.1e-06 25.2 0.0 1.1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Mad3_BUB1_II PF08171.6 EIW84278.1 - 0.024 14.5 0.0 0.063 13.1 0.0 1.6 1 0 0 1 1 1 0 Mad3/BUB1 homology region 2 MFS_1 PF07690.11 EIW84281.1 - 8.6e-33 113.4 21.9 8.6e-33 113.4 15.2 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW84281.1 - 1.6e-15 56.6 2.5 1.6e-15 56.6 1.7 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter BT1 PF03092.11 EIW84281.1 - 0.00018 20.3 1.4 0.00048 18.9 0.1 2.1 1 1 0 2 2 2 1 BT1 family DUF4131 PF13567.1 EIW84281.1 - 0.067 12.5 9.5 0.21 10.9 0.0 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) ExbD PF02472.11 EIW84281.1 - 0.081 12.9 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Biopolymer transport protein ExbD/TolR Arrestin_N PF00339.24 EIW84282.1 - 4.9e-07 29.6 0.0 4.9e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain DUF544 PF04424.8 EIW84283.1 - 3.1e-16 59.2 0.0 6.1e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF544) 2-Hacid_dh_C PF02826.14 EIW84284.1 - 9.1e-50 168.2 0.0 1.2e-49 167.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIW84284.1 - 3e-16 59.1 0.0 4.4e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EIW84284.1 - 0.0011 18.8 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase adh_short PF00106.20 EIW84284.1 - 0.11 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Glyco_hydro_3 PF00933.16 EIW84285.1 - 5.4e-74 248.8 0.0 8.6e-74 248.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIW84285.1 - 8.5e-70 234.8 0.2 1.1e-68 231.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIW84285.1 - 1.2e-18 66.7 0.0 2.7e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EIW84285.1 - 8.8e-07 28.6 0.0 1.7e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 PA14 domain SPX PF03105.14 EIW84286.1 - 3e-41 142.0 0.0 4.9e-41 141.3 0.0 1.4 1 0 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EIW84286.1 - 3.7e-35 121.7 29.0 5e-35 121.2 20.1 1.2 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EIW84286.1 - 7.1e-20 70.8 29.9 7e-16 57.7 8.3 2.3 2 1 1 3 3 3 2 Citrate transporter YL1 PF05764.8 EIW84286.1 - 0.057 13.0 1.0 0.089 12.3 0.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DUF1956 PF09209.6 EIW84286.1 - 0.058 13.3 0.1 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1956) zf-MYND PF01753.13 EIW84287.1 - 1.9e-07 30.7 14.1 3.6e-07 29.9 9.8 1.4 1 0 0 1 1 1 1 MYND finger Cpn10 PF00166.16 EIW84288.1 - 2.8e-26 91.2 0.0 3.2e-26 91.0 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit MFS_1 PF07690.11 EIW84289.1 - 1.8e-43 148.6 55.9 1.3e-30 106.3 13.6 3.2 1 1 2 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW84289.1 - 3.1e-08 32.6 5.8 3.1e-08 32.6 4.0 3.3 3 1 0 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EIW84289.1 - 5.5e-05 21.5 8.3 5.5e-05 21.5 5.7 2.0 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 EIW84290.1 - 2.3e-66 224.2 0.0 2.7e-66 224.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AhpC-TSA_2 PF13911.1 EIW84291.1 - 6.1e-15 55.1 0.0 1.5e-14 53.8 0.0 1.6 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EIW84291.1 - 3.4e-08 33.2 0.0 6.7e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIW84291.1 - 1.3e-05 24.7 0.0 3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.1 EIW84291.1 - 0.11 12.6 0.0 2 8.6 0.0 2.3 2 0 0 2 2 2 0 Thioredoxin-like domain Aa_trans PF01490.13 EIW84292.1 - 2.3e-87 293.1 33.9 2.7e-87 292.9 23.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Harakiri PF15196.1 EIW84292.1 - 0.085 13.1 1.1 0.37 11.0 0.0 2.5 2 0 0 2 2 2 0 Activator of apoptosis harakiri p450 PF00067.17 EIW84293.1 - 1.3e-74 251.3 0.0 1.6e-74 251.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_trans_1_3 PF13528.1 EIW84294.1 - 1.1e-11 44.4 0.0 1.1e-09 37.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 1 PTPlike_phytase PF14566.1 EIW84295.1 - 9.9e-121 398.8 0.0 3.1e-39 134.3 0.0 3.4 3 0 0 3 3 3 3 Inositol hexakisphosphate DSPc PF00782.15 EIW84295.1 - 9.5e-08 31.6 0.0 0.001 18.6 0.0 3.3 3 0 0 3 3 3 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIW84295.1 - 8.9e-07 28.4 0.0 0.07 12.4 0.0 3.4 3 0 0 3 3 3 2 Protein-tyrosine phosphatase TFIIE-A_C-term PF11521.3 EIW84295.1 - 0.00011 22.0 0.0 1.5 8.8 0.0 3.5 3 0 0 3 3 3 2 C-terminal general transcription factor TFIIE alpha CDKN3 PF05706.7 EIW84295.1 - 0.18 11.2 0.0 0.45 9.9 0.0 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) VTC PF09359.5 EIW84297.1 - 1.1e-98 329.7 0.3 1.1e-97 326.4 0.0 2.2 3 0 0 3 3 3 1 VTC domain SPX PF03105.14 EIW84297.1 - 2.2e-27 96.5 3.5 4.4e-25 89.0 2.4 2.5 1 1 0 1 1 1 1 SPX domain DUF202 PF02656.10 EIW84297.1 - 3.5e-09 36.7 4.7 7e-09 35.7 3.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF202) Herpes_UL25 PF01499.11 EIW84297.1 - 0.0011 17.3 2.5 0.0031 15.8 0.4 2.0 2 0 0 2 2 2 1 Herpesvirus UL25 family Luteo_P1-P2 PF08467.5 EIW84297.1 - 0.019 13.7 0.1 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase Gtr1_RagA PF04670.7 EIW84298.1 - 2.3e-54 184.0 0.0 2.9e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EIW84298.1 - 8.9e-05 22.9 0.0 0.00019 21.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AAA_10 PF12846.2 EIW84298.1 - 0.0085 15.5 0.0 0.015 14.7 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain Ras PF00071.17 EIW84298.1 - 0.018 14.4 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Ras family Arf PF00025.16 EIW84298.1 - 0.02 14.1 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_14 PF13173.1 EIW84298.1 - 0.02 14.7 0.0 0.049 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.5 EIW84298.1 - 0.021 14.0 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 EIW84298.1 - 0.049 13.3 0.0 0.12 12.0 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase MMR_HSR1 PF01926.18 EIW84298.1 - 0.099 12.6 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF390 PF04094.9 EIW84298.1 - 0.26 9.2 1.4 0.32 8.9 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF390) Phosphoprotein PF00922.12 EIW84298.1 - 0.77 8.9 4.4 1.3 8.1 3.1 1.3 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Acyl_transf_1 PF00698.16 EIW84299.1 - 4.8e-66 223.2 0.1 1.7e-64 218.1 0.0 2.9 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EIW84299.1 - 5.7e-29 99.9 0.0 2.4e-28 98.0 0.0 2.1 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 EIW84299.1 - 5e-28 96.6 0.8 1.4e-27 95.1 0.6 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1729) ketoacyl-synt PF00109.21 EIW84299.1 - 3.4e-25 89.0 0.4 8.5e-25 87.6 0.3 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EIW84299.1 - 3.2e-19 69.6 0.0 7e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Ketoacyl-synt_C PF02801.17 EIW84299.1 - 1.1e-14 54.2 0.3 2.7e-14 53.0 0.2 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACPS PF01648.15 EIW84299.1 - 8.4e-14 51.3 0.0 2.3e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily adh_short PF00106.20 EIW84299.1 - 0.00027 20.8 2.2 0.0067 16.3 0.0 3.1 3 0 0 3 3 3 1 short chain dehydrogenase Abhydrolase_5 PF12695.2 EIW84299.1 - 0.0075 16.0 0.1 0.44 10.3 0.0 3.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family cIII PF08134.6 EIW84300.1 - 0.13 11.8 0.7 9.6 5.9 0.1 2.4 2 0 0 2 2 2 0 cIII protein family DEAD PF00270.24 EIW84301.1 - 4.9e-33 114.0 0.5 2.1e-32 111.9 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW84301.1 - 1.4e-23 82.5 0.2 2.9e-23 81.5 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EIW84301.1 - 0.043 13.9 2.0 0.35 11.0 0.5 2.7 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EIW84301.1 - 0.062 12.8 0.1 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Helicase_C_2 PF13307.1 EIW84301.1 - 0.11 12.4 0.0 0.38 10.6 0.0 1.9 2 0 0 2 2 2 0 Helicase C-terminal domain DUF202 PF02656.10 EIW84302.1 - 9.2e-10 38.6 2.1 9.2e-10 38.6 1.5 1.9 3 0 0 3 3 3 1 Domain of unknown function (DUF202) DnaJ PF00226.26 EIW84303.1 - 3.5e-27 93.9 0.8 5.3e-27 93.3 0.5 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EIW84303.1 - 6.5e-21 74.0 0.4 1.4e-18 66.5 0.1 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 EIW84304.1 - 4.3e-16 58.4 0.2 5.2e-16 58.1 0.1 1.1 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.17 EIW84304.1 - 0.0082 15.7 0.0 0.014 15.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NeA_P2 PF12312.3 EIW84304.1 - 0.033 13.4 2.1 0.034 13.3 1.4 1.1 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein Mito_fiss_reg PF05308.6 EIW84304.1 - 0.043 13.1 2.0 0.043 13.1 1.4 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CTDII PF01556.13 EIW84305.1 - 3.8e-10 39.5 0.1 4.8e-07 29.5 0.0 2.2 2 0 0 2 2 2 2 DnaJ C terminal domain Laminin_B PF00052.13 EIW84305.1 - 0.071 12.7 0.0 4.2 6.9 0.0 2.1 2 0 0 2 2 2 0 Laminin B (Domain IV) Drf_GBD PF06371.8 EIW84307.1 - 4.8e-15 55.4 0.0 2.6e-13 49.7 0.0 2.8 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Fungal_trans_2 PF11951.3 EIW84308.1 - 4e-32 111.2 0.4 4.9e-32 110.9 0.2 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain Csm1 PF12539.3 EIW84308.1 - 0.035 14.5 0.0 0.3 11.5 0.0 2.1 2 0 0 2 2 2 0 Chromosome segregation protein Csm1/Pcs1 Zn_clus PF00172.13 EIW84309.1 - 6.2e-07 29.2 9.9 8.6e-07 28.7 6.8 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EIW84309.1 - 5.6 7.1 13.7 8.3 6.6 3.8 2.2 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region Fungal_trans_2 PF11951.3 EIW84310.1 - 1.1e-40 139.4 1.8 1.1e-40 139.4 1.2 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW84310.1 - 0.00011 22.0 7.4 0.00026 20.8 5.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1258 PF06869.7 EIW84310.1 - 0.026 13.6 0.0 0.059 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1258) DUF605 PF04652.11 EIW84310.1 - 0.064 12.6 6.5 0.098 12.0 4.5 1.2 1 0 0 1 1 1 0 Vta1 like PH PF00169.24 EIW84311.1 - 2.6e-33 114.3 0.6 4.1e-19 68.7 0.2 2.4 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EIW84311.1 - 3.4e-15 56.2 9.9 3.9e-07 30.3 2.7 3.7 2 2 0 2 2 2 2 Pleckstrin homology domain PH_8 PF15409.1 EIW84311.1 - 1.3e-06 28.3 2.0 0.00015 21.7 0.2 2.5 3 0 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.1 EIW84311.1 - 1.3e-05 25.3 1.9 0.1 12.7 0.5 2.8 2 1 0 2 2 2 2 Pleckstrin homology domain Mcp5_PH PF12814.2 EIW84311.1 - 0.048 13.5 8.2 1.2 9.0 0.0 3.1 3 1 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology Glyoxalase PF00903.20 EIW84311.1 - 0.093 12.7 0.1 0.77 9.7 0.0 2.1 2 0 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily PH_4 PF15404.1 EIW84311.1 - 0.094 12.2 0.2 0.61 9.5 0.0 2.3 2 1 1 3 3 3 0 Pleckstrin homology domain DUF3597 PF12200.3 EIW84311.1 - 0.22 11.9 4.5 3.6 7.9 0.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3597) ACBP PF00887.14 EIW84312.1 - 4.5e-33 112.7 0.7 5.2e-33 112.5 0.5 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein BING4CT PF08149.6 EIW84312.1 - 0.053 13.0 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 BING4CT (NUC141) domain Kelch_4 PF13418.1 EIW84313.1 - 3.8e-20 71.3 4.5 4.6e-05 23.0 0.0 6.7 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EIW84313.1 - 8.9e-19 67.0 1.4 2.4e-06 27.3 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.1 EIW84313.1 - 4.4e-15 55.1 2.8 0.0075 16.4 0.1 5.0 3 1 1 4 4 4 4 Kelch motif Kelch_1 PF01344.20 EIW84313.1 - 1.4e-05 24.5 5.3 0.61 9.6 0.0 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 EIW84313.1 - 0.00013 21.6 1.0 0.18 11.6 0.0 4.2 4 0 0 4 4 4 1 Kelch motif Hydrophobin PF01185.13 EIW84314.1 - 4.7e-18 65.4 8.9 5.5e-18 65.1 6.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Sp38 PF07354.7 EIW84314.1 - 3.7 6.1 5.2 1.5 7.3 2.0 1.4 2 0 0 2 2 2 0 Zona-pellucida-binding protein (Sp38) p450 PF00067.17 EIW84316.1 - 9.9e-54 182.5 0.0 1.3e-53 182.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fra10Ac1 PF09725.4 EIW84317.1 - 0.00069 19.6 1.5 0.002 18.1 0.9 2.1 1 1 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 Toxin_13 PF07822.6 EIW84317.1 - 6.2 6.8 7.2 9.5 6.2 0.2 3.0 3 0 0 3 3 3 0 Neurotoxin B-IV-like protein Carn_acyltransf PF00755.15 EIW84318.1 - 1e-134 449.8 0.0 1.2e-134 449.6 0.0 1.1 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase AAA_12 PF13087.1 EIW84319.1 - 3.9e-32 111.2 0.0 7.4e-32 110.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIW84319.1 - 2.7e-17 63.1 0.0 2.2e-07 30.6 0.0 2.2 1 1 1 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EIW84319.1 - 1.2e-08 34.8 0.0 0.00014 21.4 0.0 2.3 1 1 1 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EIW84319.1 - 9.8e-08 31.6 0.0 2.4e-07 30.4 0.0 1.6 2 0 0 2 2 1 1 Part of AAA domain AAA_30 PF13604.1 EIW84319.1 - 2.9e-07 30.2 0.0 2.6e-06 27.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain DEAD PF00270.24 EIW84319.1 - 4.7e-06 26.1 0.0 1.4e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EIW84319.1 - 1.1e-05 25.5 0.0 0.00022 21.3 0.0 2.3 1 1 1 2 2 2 1 AAA domain Helicase_RecD PF05127.9 EIW84319.1 - 0.0013 18.4 0.0 0.0068 16.0 0.0 2.0 1 1 0 1 1 1 1 Helicase ResIII PF04851.10 EIW84319.1 - 0.0016 18.3 0.0 0.011 15.6 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_33 PF13671.1 EIW84319.1 - 0.0025 17.6 0.0 0.035 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EIW84319.1 - 0.0032 16.8 0.0 0.0064 15.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EIW84319.1 - 0.015 14.2 1.4 1.6 7.6 0.0 2.9 2 2 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 EIW84319.1 - 0.024 14.0 0.0 0.068 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_16 PF13191.1 EIW84319.1 - 0.034 14.1 0.0 0.091 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Zot PF05707.7 EIW84319.1 - 0.052 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) SNF2_N PF00176.18 EIW84319.1 - 0.053 12.3 0.0 0.079 11.7 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA PF00004.24 EIW84319.1 - 0.081 13.1 0.0 0.18 11.9 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EIW84319.1 - 0.11 11.8 0.1 0.45 9.9 0.1 1.9 1 1 1 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.1 EIW84319.1 - 0.13 11.8 0.2 0.34 10.4 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain RNA_helicase PF00910.17 EIW84319.1 - 0.15 12.2 0.1 0.45 10.7 0.0 1.9 2 1 0 2 2 2 0 RNA helicase DUF1767 PF08585.7 EIW84320.1 - 5.6e-07 29.7 0.0 8.1e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) SWI-SNF_Ssr4 PF08549.5 EIW84321.1 - 0.1 10.8 5.3 0.1 10.8 3.7 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) DnaJ PF00226.26 EIW84322.1 - 2.2e-17 62.5 0.4 2.2e-17 62.5 0.3 1.8 2 0 0 2 2 2 1 DnaJ domain CtaG_Cox11 PF04442.9 EIW84323.1 - 8.6e-57 191.2 0.0 1.2e-56 190.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 PH_9 PF15410.1 EIW84324.1 - 0.035 14.2 0.0 0.075 13.1 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Nucleoplasmin PF03066.10 EIW84324.1 - 0.44 10.0 6.7 1 8.8 4.7 1.5 1 0 0 1 1 1 0 Nucleoplasmin XPG_N PF00752.12 EIW84325.1 - 4.5e-28 97.4 0.0 8.8e-28 96.5 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EIW84325.1 - 4.6e-25 87.4 0.0 9.1e-25 86.5 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.2 EIW84325.1 - 0.0014 18.2 0.0 0.0028 17.1 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.15 EIW84325.1 - 0.044 14.0 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold OGFr_N PF04664.8 EIW84325.1 - 0.077 12.3 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Opioid growth factor receptor (OGFr) conserved region NDUF_B8 PF05821.6 EIW84326.1 - 8.7e-10 38.5 0.3 1.7e-09 37.5 0.2 1.5 1 1 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Methyltransf_11 PF08241.7 EIW84327.1 - 1.8e-15 57.1 0.0 4e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW84327.1 - 8.1e-13 48.4 0.0 2.3e-12 46.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW84327.1 - 1.2e-12 48.4 0.0 3e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW84327.1 - 4.3e-10 39.8 0.0 8.2e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW84327.1 - 5.9e-10 38.6 0.0 9.3e-10 38.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EIW84327.1 - 2.6e-08 34.2 0.0 5.9e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW84327.1 - 4.4e-08 33.1 0.0 7.3e-07 29.2 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW84327.1 - 2.4e-07 30.4 0.0 5e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW84327.1 - 2e-05 24.0 0.0 3.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EIW84327.1 - 0.00095 18.2 0.0 0.019 13.9 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.10 EIW84327.1 - 0.0013 18.4 0.0 0.11 12.1 0.0 2.1 2 0 0 2 2 2 1 Hypothetical methyltransferase FtsJ PF01728.14 EIW84327.1 - 0.0029 17.5 0.0 0.0057 16.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 EIW84327.1 - 0.027 13.6 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase PrmA PF06325.8 EIW84327.1 - 0.059 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 EIW84327.1 - 0.1 11.5 0.0 1.4 7.8 0.0 2.1 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_29 PF03141.11 EIW84327.1 - 0.12 10.7 0.0 0.2 9.9 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Peptidase_M24 PF00557.19 EIW84328.1 - 9.4e-27 93.9 0.4 1.3e-26 93.4 0.3 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Speriolin_N PF15058.1 EIW84328.1 - 0.013 15.3 0.1 0.063 13.1 0.0 2.0 2 0 0 2 2 2 0 Speriolin N terminus TyeA PF09059.5 EIW84328.1 - 0.093 12.6 0.1 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 TyeA p450 PF00067.17 EIW84329.1 - 1.6e-49 168.6 0.0 2.8e-49 167.9 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Citrate_synt PF00285.16 EIW84331.1 - 2.4e-115 385.0 0.0 2.9e-115 384.8 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase PHD PF00628.24 EIW84332.1 - 0.0048 16.5 10.0 0.0048 16.5 6.9 3.0 3 0 0 3 3 3 1 PHD-finger Kinesin-related PF06548.6 EIW84332.1 - 0.52 8.8 0.0 0.86 8.0 0.0 1.2 1 0 0 1 1 1 0 Kinesin-related NSP2-B_epitope PF14757.1 EIW84335.1 - 0.0034 16.8 0.7 0.13 11.7 1.3 2.1 2 0 0 2 2 2 1 Immunogenic region of nsp2 protein of arterivirus polyprotein Cauli_VI PF01693.11 EIW84335.1 - 0.046 13.7 0.0 0.079 12.9 0.0 1.3 1 0 0 1 1 1 0 Caulimovirus viroplasmin TPR_11 PF13414.1 EIW84337.1 - 3.6e-10 39.3 10.5 6.8e-07 28.8 1.1 2.6 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EIW84337.1 - 2.9e-05 23.6 6.9 0.024 14.5 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIW84337.1 - 0.00035 20.9 0.5 0.26 12.0 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIW84337.1 - 0.00065 19.9 1.6 0.00065 19.9 1.1 2.2 2 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EIW84337.1 - 0.00079 19.5 1.9 0.0011 19.0 0.2 2.0 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EIW84337.1 - 0.0016 19.0 6.7 2 9.1 0.3 3.5 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EIW84337.1 - 0.0085 16.0 0.8 0.087 12.7 0.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EIW84337.1 - 0.33 10.6 6.9 0.98 9.1 0.1 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIW84337.1 - 0.49 10.9 2.5 62 4.3 0.0 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 EIW84337.1 - 0.58 10.3 6.1 0.12 12.5 0.8 2.3 2 1 0 2 2 2 0 Tetratricopeptide repeat Ribosomal_60s PF00428.14 EIW84337.1 - 3.3 8.1 10.2 0.21 12.0 2.5 2.2 1 1 1 2 2 2 0 60s Acidic ribosomal protein COesterase PF00135.23 EIW84339.1 - 2e-89 300.7 2.4 4.7e-89 299.5 1.7 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW84339.1 - 1.7e-05 24.5 0.5 9.2e-05 22.1 0.4 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Semenogelin PF05474.6 EIW84340.1 - 0.064 11.5 4.7 0.14 10.4 0.6 2.0 2 0 0 2 2 2 0 Semenogelin AAA_12 PF13087.1 EIW84341.1 - 9.6e-31 106.7 0.5 2e-30 105.6 0.3 1.5 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIW84341.1 - 4.5e-11 42.7 0.5 5.5e-08 32.6 0.0 2.5 2 1 1 3 3 3 2 AAA domain AAA_30 PF13604.1 EIW84341.1 - 0.0013 18.3 0.0 0.0023 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Aldo_ket_red PF00248.16 EIW84342.1 - 7.2e-42 143.1 0.0 1.1e-41 142.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.17 EIW84343.1 - 2.8e-67 227.2 0.0 3.3e-67 227.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NTP_transf_5 PF14907.1 EIW84343.1 - 0.088 12.1 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase Amino_oxidase PF01593.19 EIW84344.1 - 2.5e-35 122.4 0.1 2.1e-23 83.1 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EIW84344.1 - 1.3e-09 37.9 0.0 6e-09 35.7 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain p450 PF00067.17 EIW84345.1 - 4.6e-43 147.4 0.0 7.7e-29 100.5 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 AAA_12 PF13087.1 EIW84346.1 - 2.6e-23 82.4 0.2 3.8e-23 81.9 0.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EIW84346.1 - 6.2e-11 42.3 0.2 2.7e-07 30.3 0.0 2.8 2 1 1 3 3 3 2 AAA domain Viral_helicase1 PF01443.13 EIW84346.1 - 4.7e-05 23.0 0.0 6.7e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EIW84346.1 - 0.0056 16.2 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Peptidase_C48 PF02902.14 EIW84350.1 - 2.3e-14 53.5 0.1 4.9e-14 52.4 0.1 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain p450 PF00067.17 EIW84351.1 - 7.4e-41 140.1 0.0 6e-26 90.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 OPT PF03169.10 EIW84353.1 - 9.1e-135 450.5 21.8 1.5e-134 449.8 15.1 1.3 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Lysis_S PF04971.7 EIW84353.1 - 0.017 14.8 4.5 6.3 6.5 0.0 4.2 4 0 0 4 4 4 0 Lysis protein S DUF1183 PF06682.7 EIW84354.1 - 2.6e-59 201.3 11.8 1.6e-58 198.8 8.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) DUF1206 PF06724.6 EIW84354.1 - 0.012 15.3 0.4 0.028 14.1 0.2 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1206) MFS_1 PF07690.11 EIW84355.1 - 6.6e-15 54.6 50.7 2.3e-14 52.8 22.9 3.2 1 1 2 3 3 3 2 Major Facilitator Superfamily Serglycin PF04360.7 EIW84356.1 - 0.021 14.5 0.2 0.042 13.5 0.1 1.4 1 0 0 1 1 1 0 Serglycin tRNA-synt_1g PF09334.6 EIW84357.1 - 5.7e-130 433.4 0.0 7.2e-130 433.1 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) WHEP-TRS PF00458.15 EIW84357.1 - 2.8e-08 33.2 10.1 2.8e-08 33.2 7.0 1.8 2 0 0 2 2 2 1 WHEP-TRS domain tRNA-synt_1 PF00133.17 EIW84357.1 - 1.7e-05 23.0 0.0 0.01 13.8 0.0 3.3 2 2 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EIW84357.1 - 7.6e-05 22.5 0.0 0.00018 21.3 0.0 1.8 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA DUF1610 PF07754.6 EIW84357.1 - 0.33 11.0 4.8 0.72 10.0 3.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) DUF1272 PF06906.6 EIW84357.1 - 0.9 9.4 6.5 0.077 12.8 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) DUF1289 PF06945.8 EIW84357.1 - 1.6 8.2 5.1 4 6.9 1.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1289) p450 PF00067.17 EIW84358.1 - 1.7e-74 251.0 0.0 1.9e-74 250.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW84359.1 - 2.2e-41 141.8 0.0 2.8e-20 72.2 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 NeA_P2 PF12312.3 EIW84359.1 - 0.032 13.4 1.7 0.054 12.7 1.2 1.3 1 0 0 1 1 1 0 Nepovirus subgroup A polyprotein p450 PF00067.17 EIW84360.1 - 4.2e-72 243.1 0.0 4.9e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EIW84361.1 - 0.0003 20.4 0.2 0.0003 20.4 0.2 2.3 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EIW84361.1 - 0.0064 16.1 0.3 0.017 14.7 0.2 1.8 1 0 0 1 1 1 1 F-box domain Aminotran_5 PF00266.14 EIW84363.1 - 2.4e-13 49.6 0.0 1.3e-06 27.4 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V Aminotran_1_2 PF00155.16 EIW84363.1 - 0.0059 15.5 0.0 0.019 13.9 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Cytochrom_C_2 PF01322.15 EIW84363.1 - 0.12 12.9 0.1 0.22 12.0 0.1 1.4 1 0 0 1 1 1 0 Cytochrome C' Bud13 PF09736.4 EIW84364.1 - 5.7e-46 156.3 4.0 5.7e-46 156.3 2.8 2.4 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex Cytomega_UL20A PF05984.7 EIW84364.1 - 0.01 15.9 0.9 0.01 15.9 0.6 2.2 1 1 1 2 2 2 0 Cytomegalovirus UL20A protein HSP20 PF00011.16 EIW84365.1 - 7.1e-10 38.6 0.0 1.4e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 Hsp20/alpha crystallin family MIP-T3 PF10243.4 EIW84365.1 - 1.1 7.5 11.3 1.5 7.1 7.8 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PRP38_assoc PF12871.2 EIW84365.1 - 5.5 7.5 49.6 5.8 7.5 18.9 2.6 1 1 1 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term EHN PF06441.7 EIW84367.1 - 1.7e-32 111.6 0.0 7.1e-32 109.6 0.0 1.9 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EIW84367.1 - 1.6e-08 34.6 1.4 6.8e-08 32.6 0.4 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW84367.1 - 5.5e-05 22.8 0.1 9.9e-05 21.9 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold p450 PF00067.17 EIW84368.1 - 1.2e-73 248.2 0.0 1.5e-73 247.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UvrD_C PF13361.1 EIW84369.1 - 5e-79 266.3 0.0 1.4e-78 264.8 0.0 1.7 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EIW84369.1 - 2e-62 211.3 0.0 4.2e-62 210.2 0.0 1.6 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EIW84369.1 - 1.2e-13 51.0 0.0 3.1e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EIW84369.1 - 2.1e-13 49.7 0.1 5.1e-12 45.3 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain Viral_helicase1 PF01443.13 EIW84369.1 - 2.9e-07 30.2 0.2 0.078 12.4 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EIW84369.1 - 0.0011 18.5 0.0 0.08 12.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EIW84369.1 - 0.017 14.5 0.0 0.11 11.9 0.0 2.3 2 1 1 3 3 3 0 AAA domain ApbA_C PF08546.6 EIW84369.1 - 0.021 14.8 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Sugar_tr PF00083.19 EIW84370.1 - 2.3e-112 375.8 23.5 3.4e-112 375.3 16.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW84370.1 - 5.2e-26 91.1 45.8 4.5e-16 58.5 11.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_C14 PF00656.17 EIW84371.1 - 4.2e-71 239.5 0.0 5.1e-71 239.2 0.0 1.0 1 0 0 1 1 1 1 Caspase domain Metallophos_2 PF12850.2 EIW84372.1 - 2.3e-08 34.0 0.0 4.6e-08 33.0 0.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EIW84372.1 - 3.7e-06 26.4 0.1 8.7e-06 25.2 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase AIG2 PF06094.7 EIW84373.1 - 7.2e-13 48.9 0.0 1.2e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 AIG2-like family Aminotran_5 PF00266.14 EIW84374.1 - 2.5e-08 33.0 0.0 0.0017 17.1 0.0 2.1 2 0 0 2 2 2 2 Aminotransferase class-V SSP160 PF06933.6 EIW84374.1 - 0.061 11.3 0.8 0.088 10.7 0.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Cytochrom_C_2 PF01322.15 EIW84374.1 - 0.067 13.7 0.2 0.44 11.1 0.0 2.1 2 0 0 2 2 2 0 Cytochrome C' Chlorovi_GP_rpt PF06598.6 EIW84374.1 - 0.21 11.4 3.5 0.5 10.2 2.4 1.7 1 0 0 1 1 1 0 Chlorovirus glycoprotein repeat p450 PF00067.17 EIW84375.1 - 3.3e-70 236.8 0.0 4.3e-70 236.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF2392 PF10288.4 EIW84376.1 - 2.1e-09 37.6 0.0 7.7e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2392) ATP_bind_3 PF01171.15 EIW84376.1 - 0.1 12.0 0.5 1.8 8.0 0.2 2.4 2 0 0 2 2 2 0 PP-loop family DUF2415 PF10313.4 EIW84377.1 - 4e-06 26.4 0.1 1.5e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein domain (DUF2415) CDC45 PF02724.9 EIW84377.1 - 1.6 6.7 8.0 0.28 9.1 2.1 1.9 2 0 0 2 2 2 0 CDC45-like protein RRM_5 PF13893.1 EIW84378.1 - 1.5e-06 27.9 0.0 2.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIW84378.1 - 4.1e-05 23.1 0.0 8.3e-05 22.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW84378.1 - 0.00019 21.3 0.0 0.00034 20.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIW84378.1 - 0.00028 20.6 0.0 0.00051 19.7 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-C2H2_4 PF13894.1 EIW84379.1 - 5e-08 32.7 7.7 0.0011 19.1 1.8 2.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIW84379.1 - 3.7e-06 26.9 0.4 3.7e-06 26.9 0.2 2.9 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2 PF00096.21 EIW84379.1 - 2.7e-05 24.2 10.2 0.026 14.8 3.3 2.2 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.2 EIW84379.1 - 0.034 14.3 6.3 1.4 9.2 2.2 2.2 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-CCHC_5 PF14787.1 EIW84379.1 - 0.061 12.8 3.6 0.091 12.2 2.5 1.3 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger cEGF PF12662.2 EIW84379.1 - 0.085 12.5 1.4 0.15 11.7 0.9 1.4 1 0 0 1 1 1 0 Complement Clr-like EGF-like YhfH PF14149.1 EIW84379.1 - 0.099 12.4 0.5 0.16 11.7 0.3 1.3 1 0 0 1 1 1 0 YhfH-like protein TNFR_c6 PF00020.13 EIW84379.1 - 0.12 12.4 1.6 0.2 11.7 1.1 1.4 1 0 0 1 1 1 0 TNFR/NGFR cysteine-rich region zf-C2HC_2 PF13913.1 EIW84379.1 - 0.14 11.8 3.3 0.31 10.7 2.3 1.7 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 EIW84379.1 - 0.15 12.2 7.7 0.96 9.6 2.8 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 EIW84379.1 - 1.6 8.7 4.5 5.8 6.9 1.2 2.4 1 1 1 2 2 2 0 Zinc ribbon domain zf-C2H2_2 PF12756.2 EIW84379.1 - 2.2 8.4 5.7 12 6.1 1.8 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) APH PF01636.18 EIW84382.1 - 1.1e-06 28.5 0.1 2.5e-06 27.4 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family COX5B PF01215.14 EIW84383.1 - 4.2e-39 133.3 0.0 5.1e-39 133.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-RING_4 PF14570.1 EIW84383.1 - 0.081 12.5 0.2 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.5 EIW84383.1 - 0.11 12.4 0.1 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Zinc ribbon domain DNA_ligase_ZBD PF03119.11 EIW84383.1 - 0.12 12.1 1.2 0.81 9.4 0.2 2.4 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain Na_Ca_ex PF01699.19 EIW84384.1 - 7.5e-25 87.1 39.3 2.8e-14 52.9 10.4 3.3 3 0 0 3 3 3 3 Sodium/calcium exchanger protein MscL PF01741.13 EIW84384.1 - 0.12 12.5 0.0 0.12 12.5 0.0 2.3 3 1 0 3 3 3 0 Large-conductance mechanosensitive channel, MscL PRK PF00485.13 EIW84385.1 - 4.9e-50 169.7 0.0 7.9e-50 169.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 EIW84385.1 - 7.2e-49 165.7 0.0 1.4e-46 158.3 0.0 2.3 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase AAA_18 PF13238.1 EIW84385.1 - 7.4e-05 23.0 0.0 0.00019 21.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW84385.1 - 0.00014 22.6 0.0 0.00051 20.8 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 EIW84385.1 - 0.00031 20.6 0.0 0.0011 18.8 0.0 2.0 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIW84385.1 - 0.0064 15.6 0.0 0.017 14.2 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin CoaE PF01121.15 EIW84385.1 - 0.027 13.8 0.1 0.71 9.2 0.0 2.3 2 0 0 2 2 2 0 Dephospho-CoA kinase CPT PF07931.7 EIW84385.1 - 0.039 13.5 0.1 0.13 11.8 0.0 1.9 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.1 EIW84385.1 - 0.06 13.1 0.1 6.7 6.5 0.0 3.3 4 0 0 4 4 4 0 Part of AAA domain AAA_14 PF13173.1 EIW84385.1 - 0.069 13.0 0.0 9.9 6.0 0.0 3.3 3 1 1 4 4 4 0 AAA domain dNK PF01712.14 EIW84385.1 - 0.15 11.9 0.0 0.68 9.8 0.0 2.0 1 1 0 1 1 1 0 Deoxynucleoside kinase DUF2392 PF10288.4 EIW84386.1 - 1.6e-09 38.0 0.0 5.8e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2392) DZR PF12773.2 EIW84386.1 - 3 7.7 4.9 9.7 6.1 0.2 2.8 2 1 0 2 2 2 0 Double zinc ribbon Gin PF10764.4 EIW84386.1 - 5.9 6.6 6.5 4.9 6.9 0.1 2.9 3 0 0 3 3 3 0 Inhibitor of sigma-G Gin F-box-like PF12937.2 EIW84388.1 - 6.2e-08 32.2 0.2 1.6e-07 30.9 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW84388.1 - 9e-06 25.2 0.2 1.6e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 F-box domain Sporozoite_P67 PF05642.6 EIW84388.1 - 0.086 10.6 9.1 0.14 10.0 6.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ABC_membrane PF00664.18 EIW84389.1 - 6.6e-34 117.5 10.8 8e-34 117.3 7.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EIW84389.1 - 4.6e-33 114.4 0.0 8.4e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIW84389.1 - 4.9e-07 29.9 0.2 0.031 14.2 0.0 2.6 2 1 1 3 3 3 2 AAA domain SMC_N PF02463.14 EIW84389.1 - 7.7e-07 28.5 0.0 0.00012 21.3 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EIW84389.1 - 0.00052 20.0 0.0 0.0016 18.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EIW84389.1 - 0.0012 18.3 0.0 0.004 16.6 0.0 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EIW84389.1 - 0.011 16.5 0.1 0.034 14.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EIW84389.1 - 0.011 15.8 0.0 0.053 13.6 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EIW84389.1 - 0.011 15.8 0.0 0.099 12.8 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIW84389.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EIW84389.1 - 0.02 14.1 0.0 0.041 13.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 EIW84389.1 - 0.021 14.6 0.0 0.16 11.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EIW84389.1 - 0.025 14.4 0.0 0.21 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EIW84389.1 - 0.06 13.3 0.0 0.22 11.5 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase SbcCD_C PF13558.1 EIW84389.1 - 0.062 13.2 1.0 0.67 9.9 0.7 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.4 EIW84389.1 - 0.07 11.7 0.1 0.13 10.8 0.0 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_18 PF13238.1 EIW84389.1 - 0.071 13.4 0.3 0.53 10.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain G-alpha PF00503.15 EIW84389.1 - 0.16 10.6 0.0 0.3 9.7 0.0 1.4 1 0 0 1 1 1 0 G-protein alpha subunit NST1 PF13945.1 EIW84390.1 - 1.6e-19 70.7 8.7 1.6e-19 70.7 6.0 2.8 2 2 0 2 2 2 1 Salt tolerance down-regulator HNH_2 PF13391.1 EIW84391.1 - 0.0058 16.3 0.1 0.01 15.5 0.0 1.5 1 0 0 1 1 1 1 HNH endonuclease LRR_4 PF12799.2 EIW84392.1 - 5.8e-21 73.6 23.3 2.9e-08 33.1 3.1 7.7 5 3 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW84392.1 - 3e-13 49.3 22.9 8.4e-11 41.4 4.0 6.4 6 2 1 7 7 7 2 Leucine rich repeat LRR_6 PF13516.1 EIW84392.1 - 7.9e-13 47.0 13.7 0.26 11.4 0.4 9.1 11 0 0 11 11 11 4 Leucine Rich repeat LRR_7 PF13504.1 EIW84392.1 - 1.3e-10 39.6 23.0 0.019 15.0 0.6 9.1 9 0 0 9 9 9 3 Leucine rich repeat LRR_1 PF00560.28 EIW84392.1 - 2e-10 39.2 27.2 0.35 11.0 0.1 10.0 12 0 0 12 12 12 6 Leucine Rich Repeat LRR_5 PF13306.1 EIW84392.1 - 0.041 13.5 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) zf-CCCH PF00642.19 EIW84393.1 - 1.6e-05 24.4 0.8 1.6e-05 24.4 0.5 2.8 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cas_Csy2 PF09614.5 EIW84393.1 - 1.8 7.6 4.9 0.98 8.5 0.0 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csy2) TEX19 PF15553.1 EIW84394.1 - 0.067 13.0 0.6 0.19 11.6 0.4 1.8 1 0 0 1 1 1 0 Testis-expressed protein 19 PARP PF00644.15 EIW84395.1 - 2.2e-15 56.6 5.1 1.2e-12 47.6 3.6 2.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain zf-HIT PF04438.11 EIW84395.1 - 0.00046 19.7 3.2 0.00046 19.7 2.2 4.5 4 2 0 4 4 4 1 HIT zinc finger DUF329 PF03884.9 EIW84395.1 - 0.0036 16.8 1.7 0.0036 16.8 1.2 2.9 2 1 1 3 3 3 1 Domain of unknown function (DUF329) F-box PF00646.28 EIW84396.1 - 3.7e-06 26.4 0.4 4.4e-05 23.0 0.3 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EIW84396.1 - 5.5e-05 22.8 4.4 6.7e-05 22.5 0.6 2.8 3 0 0 3 3 3 1 F-box-like CBM_4_9 PF02018.12 EIW84396.1 - 0.046 13.7 0.0 0.098 12.6 0.0 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain Cytochrom_C PF00034.16 EIW84397.1 - 1.6e-08 35.2 0.1 3.3e-08 34.2 0.1 1.5 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EIW84397.1 - 5.9e-08 32.7 2.4 8.2e-07 29.0 1.6 2.0 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EIW84397.1 - 0.00088 18.7 1.4 0.0062 16.0 1.0 2.1 1 1 0 1 1 1 1 Cytochrome c-550 domain zf-CHCC PF10276.4 EIW84398.1 - 0.089 12.6 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Zinc-finger domain zf-C2H2_4 PF13894.1 EIW84398.1 - 0.11 12.9 5.7 5.3 7.6 0.2 2.8 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EIW84398.1 - 0.86 10.0 6.7 0.91 9.9 1.0 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Coq4 PF05019.8 EIW84399.1 - 3e-91 304.2 0.0 3.6e-91 304.0 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 Caudal_act PF04731.7 EIW84400.1 - 0.048 13.9 0.8 0.065 13.5 0.5 1.3 1 0 0 1 1 1 0 Caudal like protein activation region DUF1192 PF06698.6 EIW84402.1 - 0.0067 16.2 0.1 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1192) PARP PF00644.15 EIW84403.1 - 4.8e-15 55.5 2.5 2e-10 40.4 0.1 3.3 2 1 1 3 3 3 3 Poly(ADP-ribose) polymerase catalytic domain zf-HIT PF04438.11 EIW84403.1 - 0.0022 17.6 3.2 0.0022 17.6 2.2 5.1 4 2 0 4 4 4 1 HIT zinc finger DUF329 PF03884.9 EIW84403.1 - 0.0034 16.9 1.0 0.0034 16.9 0.7 3.5 2 1 1 3 3 3 1 Domain of unknown function (DUF329) Ecl1 PF12855.2 EIW84403.1 - 0.035 13.4 17.9 0.32 10.3 1.4 3.8 2 1 1 3 3 3 0 Life-span regulatory factor DUF1192 PF06698.6 EIW84404.1 - 0.28 11.0 5.1 3.2 7.6 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) ABC2_membrane PF01061.19 EIW84405.1 - 6.2e-35 120.2 23.0 6.2e-35 120.2 16.0 1.8 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.22 EIW84405.1 - 1e-26 93.8 0.0 1.7e-26 93.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIW84405.1 - 1.8e-08 34.6 0.0 1.1e-06 28.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EIW84405.1 - 0.0005 19.5 0.1 0.028 13.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EIW84405.1 - 0.00086 18.7 0.1 0.0023 17.4 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 EIW84405.1 - 0.0015 17.6 29.6 0.0015 17.6 20.5 1.7 1 1 1 2 2 2 1 ABC-2 family transporter protein DUF258 PF03193.11 EIW84405.1 - 0.0051 16.0 0.1 0.01 15.0 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 EIW84405.1 - 0.008 15.4 0.0 0.016 14.4 0.0 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain EGF_2 PF07974.8 EIW84405.1 - 0.012 15.7 9.9 0.012 15.7 6.9 4.1 4 0 0 4 4 3 0 EGF-like domain Rad17 PF03215.10 EIW84405.1 - 0.037 12.6 0.0 0.053 12.1 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein SbcCD_C PF13558.1 EIW84405.1 - 0.07 13.0 0.0 0.24 11.3 0.0 1.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 EIW84405.1 - 0.086 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 EIW84405.1 - 0.088 12.6 0.2 0.23 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EIW84405.1 - 0.12 12.5 0.0 0.35 11.0 0.0 1.9 2 1 0 2 2 1 0 AAA domain AAA_17 PF13207.1 EIW84405.1 - 0.12 13.1 0.0 0.24 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 EIW84405.1 - 0.17 10.8 0.0 8.3 5.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain hEGF PF12661.2 EIW84405.1 - 0.22 11.6 22.7 0.44 10.7 4.3 3.8 3 0 0 3 3 3 0 Human growth factor-like EGF FtsK_SpoIIIE PF01580.13 EIW84405.1 - 0.25 10.8 0.5 0.61 9.5 0.4 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Laminin_EGF PF00053.19 EIW84405.1 - 7.5 6.5 24.6 1.5 8.8 4.0 3.4 2 1 1 3 3 3 0 Laminin EGF-like (Domains III and V) Glyco_transf_22 PF03901.12 EIW84406.1 - 3.2e-37 128.5 10.2 4e-37 128.2 7.1 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.1 EIW84406.1 - 3.2 7.6 21.3 0.12 12.2 8.3 2.4 2 1 1 3 3 3 0 Dolichyl-phosphate-mannose-protein mannosyltransferase Herpes_gE PF02480.11 EIW84407.1 - 0.02 13.1 0.9 0.029 12.6 0.6 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF3433 PF11915.3 EIW84409.1 - 3.8e-17 62.2 6.3 1.3e-16 60.5 4.4 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3433) DUF4239 PF14023.1 EIW84409.1 - 0.023 14.0 0.3 0.023 14.0 0.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Mating_C PF12737.2 EIW84410.1 - 0.13 11.1 2.1 0.18 10.6 1.5 1.1 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 DUF1192 PF06698.6 EIW84410.1 - 0.39 10.5 1.8 0.42 10.4 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) PARP PF00644.15 EIW84411.1 - 3.8e-11 42.8 0.6 1.7e-09 37.4 0.1 2.9 1 1 1 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain zf-FCS PF06467.9 EIW84411.1 - 0.00062 19.3 28.0 0.0054 16.3 0.4 4.7 3 1 1 4 4 4 4 MYM-type Zinc finger with FCS sequence motif Perm-CXXC PF15629.1 EIW84411.1 - 0.02 14.8 1.4 0.11 12.5 1.0 2.3 1 0 0 1 1 1 0 Permuted single zf-CXXC unit Paired_CXXCH_1 PF09699.5 EIW84411.1 - 0.036 13.5 14.4 1.2 8.6 0.0 3.4 2 1 1 3 3 3 0 Doubled CXXCH motif (Paired_CXXCH_1) DUF1768 PF08719.6 EIW84412.1 - 8.8e-34 116.5 0.0 1.4e-33 115.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) YyzF PF14116.1 EIW84412.1 - 0.36 10.8 0.1 0.36 10.8 0.1 2.4 2 0 0 2 2 2 0 YyzF-like protein zf-FCS PF06467.9 EIW84412.1 - 1.8 8.3 19.6 3.7 7.2 3.0 3.9 2 1 1 3 3 3 0 MYM-type Zinc finger with FCS sequence motif PARP PF00644.15 EIW84413.1 - 4.5e-11 42.5 0.0 2.5e-09 36.8 0.0 2.6 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP PF00644.15 EIW84414.1 - 4e-13 49.2 1.2 6.4e-11 42.0 0.3 2.9 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain Ribosomal_L4 PF00573.17 EIW84415.1 - 2.7e-44 150.8 0.9 2.7e-44 150.8 0.6 1.9 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EIW84415.1 - 5.7e-27 93.4 1.9 5.7e-27 93.4 1.3 2.0 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain DSPc PF00782.15 EIW84417.1 - 7.1e-24 83.8 0.0 7.5e-21 74.1 0.0 3.2 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIW84417.1 - 0.071 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase p450 PF00067.17 EIW84419.1 - 1.4e-08 33.6 0.0 1.5e-08 33.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW84420.1 - 2.2e-70 237.5 0.0 2.5e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_1_2 PF00155.16 EIW84421.1 - 9.5e-19 67.5 0.0 1.2e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EIW84421.1 - 2.5e-12 46.0 0.0 3.7e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Aminotran_1_2 PF00155.16 EIW84422.1 - 3.1e-24 85.5 0.0 4.1e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EIW84422.1 - 5e-12 45.1 0.0 7.5e-12 44.5 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Pkinase PF00069.20 EIW84423.1 - 3.7e-44 150.8 0.0 7.1e-44 149.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW84423.1 - 5.2e-24 84.7 0.0 4.5e-21 75.0 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EIW84423.1 - 2.7e-06 27.3 0.0 0.0013 18.5 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW84423.1 - 0.00094 18.2 0.0 0.15 11.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Ycf9 PF01737.12 EIW84423.1 - 0.037 13.4 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 YCF9 Ino80_Iec3 PF14612.1 EIW84423.1 - 0.045 13.7 0.0 0.075 13.0 0.0 1.3 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling DUF724 PF05266.9 EIW84424.1 - 0.00067 19.3 34.7 0.0026 17.4 11.9 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF724) V_ATPase_I PF01496.14 EIW84424.1 - 0.015 13.1 14.3 0.026 12.4 9.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Baculo_PEP_C PF04513.7 EIW84424.1 - 0.11 12.3 3.5 0.26 11.1 2.4 1.6 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ADIP PF11559.3 EIW84424.1 - 0.19 11.6 37.7 2.6 7.9 19.0 3.6 3 1 0 3 3 3 0 Afadin- and alpha -actinin-Binding Reo_sigmaC PF04582.7 EIW84424.1 - 0.23 10.5 10.4 0.01 15.0 3.0 1.7 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Lebercilin PF15619.1 EIW84424.1 - 0.32 10.4 39.8 0.11 11.8 22.9 2.6 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease COG5 PF10392.4 EIW84424.1 - 0.8 9.6 15.0 4.6 7.2 7.7 2.4 2 0 0 2 2 2 0 Golgi transport complex subunit 5 p450 PF00067.17 EIW84425.1 - 5.2e-39 134.0 0.0 6.7e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW84426.1 - 1.6e-64 218.1 0.0 1.9e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 APH PF01636.18 EIW84427.1 - 0.013 15.1 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family PrpF PF04303.8 EIW84428.1 - 1.8e-70 237.5 0.4 7.9e-70 235.4 0.3 1.8 1 1 0 1 1 1 1 PrpF protein Mito_carr PF00153.22 EIW84430.1 - 4.7e-51 170.4 7.0 6e-19 67.5 0.0 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein Pex14_N PF04695.8 EIW84430.1 - 0.026 14.5 0.6 0.12 12.4 0.1 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TBPIP PF07106.8 EIW84431.1 - 1.2e-30 106.2 0.2 1.1e-26 93.4 0.2 2.1 2 0 0 2 2 2 2 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF2310 PF10071.4 EIW84431.1 - 0.0027 16.7 0.0 0.0037 16.2 0.0 1.1 1 0 0 1 1 1 1 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) DUF3475 PF11961.3 EIW84431.1 - 0.028 14.2 0.0 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3475) Penicillinase_R PF03965.11 EIW84431.1 - 0.033 14.2 0.0 0.083 12.9 0.0 1.8 1 1 0 1 1 1 0 Penicillinase repressor Tropomyosin_1 PF12718.2 EIW84431.1 - 0.044 13.6 0.5 0.044 13.6 0.4 1.7 2 0 0 2 2 2 0 Tropomyosin like HTH_IclR PF09339.5 EIW84431.1 - 0.075 12.6 0.0 0.57 9.8 0.0 2.3 2 0 0 2 2 2 0 IclR helix-turn-helix domain HALZ PF02183.13 EIW84431.1 - 0.12 12.1 1.8 0.32 10.7 1.2 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper p450 PF00067.17 EIW84432.1 - 5.5e-67 226.2 0.0 7e-67 225.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_4 PF07993.7 EIW84433.1 - 2.1e-29 102.2 0.0 3e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EIW84433.1 - 3.4e-25 88.3 0.0 2.7e-24 85.3 0.0 2.1 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EIW84433.1 - 6.9e-09 35.4 0.0 1.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EIW84433.1 - 0.015 14.9 0.0 0.033 13.8 0.0 1.5 1 0 0 1 1 1 0 KR domain PP-binding PF00550.20 EIW84433.1 - 0.097 12.9 0.0 0.26 11.5 0.0 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site adh_short PF00106.20 EIW84433.1 - 0.12 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase F-box-like PF12937.2 EIW84434.1 - 6.5e-09 35.3 0.9 6.5e-09 35.3 0.6 1.9 2 0 0 2 2 2 1 F-box-like p450 PF00067.17 EIW84435.1 - 2.5e-67 227.4 0.0 4e-67 226.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF3701 PF12482.3 EIW84435.1 - 0.023 14.4 0.4 0.06 13.0 0.2 1.6 1 0 0 1 1 1 0 Phage integrase protein HMG_box PF00505.14 EIW84438.1 - 2.9e-06 27.4 0.5 4.4e-06 26.8 0.3 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIW84438.1 - 0.0007 19.9 1.5 0.0017 18.7 1.0 1.7 1 1 0 1 1 1 1 HMG-box domain DUF4449 PF14613.1 EIW84439.1 - 4.4e-20 72.2 0.0 4.4e-20 72.2 0.0 3.9 4 1 0 4 4 4 2 Protein of unknown function (DUF4449) DUF1470 PF07336.6 EIW84439.1 - 2.6 8.4 10.3 1.2 9.4 0.3 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1470) p450 PF00067.17 EIW84440.1 - 3.5e-47 160.9 0.0 3.7e-47 160.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW84441.1 - 3e-11 42.5 0.0 3.6e-11 42.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CcmD PF04995.9 EIW84441.1 - 0.039 13.6 4.3 0.17 11.6 0.6 2.4 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) p450 PF00067.17 EIW84442.1 - 6.5e-76 255.7 0.0 7.7e-76 255.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW84443.1 - 1.3e-17 63.5 0.0 1.3e-17 63.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2977 PF11192.3 EIW84443.1 - 0.091 12.6 0.1 0.22 11.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2977) p450 PF00067.17 EIW84444.1 - 0.0019 16.8 0.0 0.002 16.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW84445.1 - 6.6e-60 202.9 0.0 8e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PS_Dcarbxylase PF02666.10 EIW84446.1 - 6.6e-52 175.7 0.0 1.1e-51 174.9 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EIW84446.1 - 6.8e-16 57.8 0.0 1.5e-15 56.7 0.0 1.6 1 0 0 1 1 1 1 C2 domain Serglycin PF04360.7 EIW84446.1 - 0.0012 18.5 3.6 0.0012 18.5 2.5 3.5 3 0 0 3 3 3 2 Serglycin HemX PF04375.9 EIW84446.1 - 0.11 11.1 14.7 0.18 10.3 10.2 1.2 1 0 0 1 1 1 0 HemX EF-hand_7 PF13499.1 EIW84446.1 - 0.16 12.1 0.0 0.31 11.2 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair Med15 PF09606.5 EIW84446.1 - 0.26 9.4 25.7 0.41 8.7 17.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4557 PF15101.1 EIW84446.1 - 0.89 9.3 9.4 1.5 8.6 6.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) PAT1 PF09770.4 EIW84446.1 - 5.2 5.1 19.7 7.2 4.7 13.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EIW84446.1 - 8.7 6.1 24.1 14 5.4 16.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit F-box-like PF12937.2 EIW84447.1 - 6e-13 48.3 0.4 1.4e-12 47.1 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW84447.1 - 0.0022 17.5 0.1 0.012 15.2 0.1 2.2 1 1 0 1 1 1 1 F-box domain p450 PF00067.17 EIW84448.1 - 1.9e-75 254.1 0.0 3.1e-56 190.8 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.17 EIW84449.1 - 8.5e-76 255.3 0.0 1e-75 255.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW84450.1 - 3.4e-62 210.4 0.0 5e-62 209.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW84451.1 - 3.2e-62 210.5 0.0 4.9e-55 186.8 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 CcmD PF04995.9 EIW84451.1 - 0.17 11.6 2.4 0.21 11.3 0.8 1.8 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) p450 PF00067.17 EIW84452.1 - 2.3e-73 247.3 0.0 2.8e-73 247.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1097 PF06496.6 EIW84452.1 - 0.074 12.8 0.1 0.48 10.2 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1097) p450 PF00067.17 EIW84453.1 - 6.8e-80 268.8 0.0 8e-80 268.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PARP PF00644.15 EIW84454.1 - 3.3e-14 52.8 0.3 3.1e-11 43.0 0.2 3.0 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain DUF329 PF03884.9 EIW84454.1 - 0.026 14.0 1.7 0.026 14.0 1.2 5.1 5 0 0 5 5 5 0 Domain of unknown function (DUF329) GnHR_trans PF12369.3 EIW84454.1 - 0.028 14.8 0.5 23 5.4 0.0 3.6 3 0 0 3 3 3 0 Gonadotropin hormone receptor transmembrane region zf-DBF PF07535.7 EIW84454.1 - 0.072 12.7 2.1 0.69 9.6 0.7 2.6 2 0 0 2 2 2 0 DBF zinc finger UPF0014 PF03649.8 EIW84455.1 - 3.1e-13 49.4 5.6 3.4e-13 49.3 3.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) Claudin_2 PF13903.1 EIW84455.1 - 0.011 15.4 0.3 0.013 15.2 0.2 1.0 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction ThiW PF09512.5 EIW84455.1 - 0.025 14.4 2.3 0.031 14.0 1.6 1.1 1 0 0 1 1 1 0 Thiamine-precursor transporter protein (ThiW) SLAC1 PF03595.12 EIW84455.1 - 0.039 12.5 1.1 0.042 12.5 0.7 1.0 1 0 0 1 1 1 0 Voltage-dependent anion channel Oxidored_q2 PF00420.19 EIW84455.1 - 0.093 12.3 2.4 0.11 12.0 1.7 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L NADH5_C PF06455.6 EIW84455.1 - 0.84 8.9 5.5 0.94 8.8 3.8 1.0 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus OATP PF03137.15 EIW84455.1 - 2 6.3 8.6 1.8 6.5 0.8 1.8 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family RCC1 PF00415.13 EIW84456.1 - 1.5e-17 63.5 5.2 0.0003 20.9 0.1 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EIW84456.1 - 2.2e-16 59.7 0.0 3.8e-08 33.2 0.0 2.7 2 1 0 2 2 2 2 BTB/POZ domain Ank_5 PF13857.1 EIW84456.1 - 8.5e-12 44.9 0.2 7.8e-06 25.9 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EIW84456.1 - 1e-11 45.0 0.3 5.6e-10 39.4 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIW84456.1 - 2.8e-11 43.6 0.0 1.7e-05 25.0 0.0 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) RCC1_2 PF13540.1 EIW84456.1 - 4.8e-08 32.4 0.1 4.8e-08 32.4 0.1 4.6 5 0 0 5 5 5 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 EIW84456.1 - 7e-07 28.8 0.1 0.081 13.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 EIW84456.1 - 3.8e-05 23.2 0.1 0.29 11.0 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat DUF1764 PF08576.5 EIW84456.1 - 0.41 11.4 1.0 1.1 10.0 0.7 1.7 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Ala_racemase_N PF01168.15 EIW84457.1 - 2.6e-22 79.4 0.5 1.8e-20 73.4 0.4 2.9 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain AgrD PF05931.6 EIW84458.1 - 0.14 11.7 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Staphylococcal AgrD protein p450 PF00067.17 EIW84460.1 - 6.8e-71 239.1 0.0 8.5e-71 238.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW84461.1 - 5e-53 180.2 0.0 6e-53 179.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UPF0014 PF03649.8 EIW84462.1 - 1.7e-46 158.4 11.9 2.3e-46 158.0 8.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) FtsX PF02687.16 EIW84462.1 - 0.01 15.5 4.2 0.01 15.5 2.9 3.6 3 2 0 3 3 3 0 FtsX-like permease family DUF4231 PF14015.1 EIW84462.1 - 0.15 12.0 8.7 0.35 10.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) Claudin_2 PF13903.1 EIW84462.1 - 2.5 7.7 17.5 0.29 10.7 1.1 3.3 1 1 2 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction BPD_transp_1 PF00528.17 EIW84462.1 - 7.6 6.0 18.1 0.049 13.1 4.8 2.2 1 1 1 2 2 2 0 Binding-protein-dependent transport system inner membrane component PARP PF00644.15 EIW84463.1 - 8.3e-16 58.0 0.6 2.4e-10 40.1 0.2 3.1 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain DUF329 PF03884.9 EIW84463.1 - 0.025 14.1 1.8 0.025 14.1 1.3 5.4 5 0 0 5 5 5 0 Domain of unknown function (DUF329) DUF2116 PF09889.4 EIW84463.1 - 0.032 14.0 1.9 0.032 14.0 1.3 2.8 3 0 0 3 3 3 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) zf-DBF PF07535.7 EIW84463.1 - 2.1 8.1 6.3 1.5 8.5 0.6 3.1 3 0 0 3 3 3 0 DBF zinc finger p450 PF00067.17 EIW84464.1 - 6.5e-80 268.8 0.0 7.8e-80 268.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW84467.1 - 1.2e-77 261.4 0.0 1.9e-77 260.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EIW84469.1 - 1.9e-09 37.1 0.0 5.2e-09 35.6 0.0 1.9 1 0 0 1 1 1 1 F-box-like Ribosomal_L39 PF00832.15 EIW84472.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal L39 protein zf-B_box PF00643.19 EIW84473.1 - 1.5 8.8 12.9 4.8 7.1 8.9 2.0 1 0 0 1 1 1 0 B-box zinc finger GalKase_gal_bdg PF10509.4 EIW84476.1 - 2.5e-05 23.4 0.1 5.4e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature Hormone_3 PF00159.13 EIW84476.1 - 2.1 8.4 4.5 1.5 8.9 0.4 2.6 3 0 0 3 3 3 0 Pancreatic hormone peptide G-alpha PF00503.15 EIW84477.1 - 5.1e-118 394.1 3.8 6.3e-118 393.8 2.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIW84477.1 - 2e-14 53.1 1.0 8.3e-09 34.9 0.2 2.5 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW84477.1 - 0.0001 21.4 0.1 0.21 10.6 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EIW84477.1 - 0.0013 19.1 0.1 0.82 10.1 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EIW84477.1 - 0.042 13.3 0.0 0.084 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EIW84477.1 - 0.054 12.9 0.1 10 5.5 0.1 2.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain DUF4243 PF14027.1 EIW84478.1 - 1.5e-51 175.8 0.0 1.8e-51 175.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) VID27 PF08553.5 EIW84480.1 - 0.033 12.4 2.6 0.056 11.6 1.8 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein BSP_II PF05432.6 EIW84480.1 - 4.6 6.4 10.0 0.18 11.0 3.0 1.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Nucleoplasmin PF03066.10 EIW84480.1 - 7.5 6.0 10.8 0.081 12.4 1.4 2.0 2 0 0 2 2 2 0 Nucleoplasmin FAM176 PF14851.1 EIW84480.1 - 9 5.9 8.0 2.2 7.9 1.8 2.2 2 0 0 2 2 2 0 FAM176 family rve PF00665.21 EIW84482.1 - 3.5e-08 33.5 0.0 3.7e-08 33.4 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIW84482.1 - 0.00039 19.8 0.0 0.00047 19.6 0.0 1.2 1 0 0 1 1 1 1 Integrase core domain UBN2_3 PF14244.1 EIW84487.1 - 2e-06 27.4 0.0 3.6e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2 PF14223.1 EIW84487.1 - 0.033 13.9 0.0 0.082 12.6 0.0 1.6 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type CytochromB561_N PF09786.4 EIW84487.1 - 1.2 7.5 10.3 1.8 6.9 7.1 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF1777 PF08648.7 EIW84487.1 - 8.4 6.0 18.4 15 5.2 12.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Rot1 PF10681.4 EIW84489.1 - 2.3e-41 141.5 7.5 9.3e-41 139.5 5.2 1.7 1 1 0 1 1 1 1 Chaperone for protein-folding within the ER, fungal DUF3796 PF12676.2 EIW84491.1 - 0.11 12.6 3.1 0.042 14.0 0.6 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) PQ-loop PF04193.9 EIW84491.1 - 0.15 11.6 3.5 1.6 8.3 0.0 2.9 2 1 1 3 3 3 0 PQ loop repeat Lon_C PF05362.8 EIW84492.1 - 2.7e-67 226.0 0.1 4.8e-67 225.2 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EIW84492.1 - 1.9e-37 128.9 0.0 4.5e-37 127.7 0.0 1.7 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EIW84492.1 - 8.1e-23 81.0 0.0 2.1e-22 79.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIW84492.1 - 5.1e-07 29.4 0.0 1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EIW84492.1 - 3.5e-06 26.5 0.0 9.9e-06 25.0 0.0 1.8 1 1 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.1 EIW84492.1 - 1.1e-05 25.4 0.2 0.00011 22.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_2 PF07724.9 EIW84492.1 - 1.3e-05 25.2 0.0 8.9e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EIW84492.1 - 3.9e-05 22.7 0.0 0.00031 19.8 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EIW84492.1 - 5.9e-05 23.8 0.1 0.00024 21.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 EIW84492.1 - 0.00025 19.8 0.0 0.00045 19.0 0.0 1.3 1 0 0 1 1 1 1 PrkA AAA domain TIP49 PF06068.8 EIW84492.1 - 0.00026 19.8 0.3 0.0074 15.0 0.1 2.6 3 0 0 3 3 3 1 TIP49 C-terminus AAA_22 PF13401.1 EIW84492.1 - 0.00036 20.6 0.1 0.0063 16.6 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EIW84492.1 - 0.0014 18.5 0.0 0.0035 17.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIW84492.1 - 0.0026 18.0 2.6 0.0037 17.5 0.1 2.4 3 0 0 3 3 2 1 AAA domain UPF0079 PF02367.12 EIW84492.1 - 0.012 15.2 0.1 0.022 14.3 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EIW84492.1 - 0.019 15.1 0.0 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 RNA helicase SKI PF01202.17 EIW84492.1 - 0.021 14.6 0.1 0.045 13.6 0.0 1.6 1 0 0 1 1 1 0 Shikimate kinase AAA_3 PF07726.6 EIW84492.1 - 0.036 13.6 0.0 0.086 12.4 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EIW84492.1 - 0.045 13.1 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein NTPase_1 PF03266.10 EIW84492.1 - 0.046 13.4 0.2 0.21 11.3 0.0 2.1 1 1 1 2 2 2 0 NTPase Arch_ATPase PF01637.13 EIW84492.1 - 0.057 13.0 0.6 6.3 6.4 0.0 2.9 2 1 1 3 3 3 0 Archaeal ATPase KaiC PF06745.8 EIW84492.1 - 0.15 11.1 0.2 1.8 7.6 0.1 2.5 2 0 0 2 2 2 0 KaiC Rad17 PF03215.10 EIW84492.1 - 0.15 10.6 0.0 0.29 9.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_23 PF13476.1 EIW84492.1 - 0.24 11.7 0.1 0.24 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2360 PF10152.4 EIW84492.1 - 7 6.9 21.2 6.2 7.0 0.9 3.6 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) p450 PF00067.17 EIW84493.1 - 1.1e-58 198.8 0.0 1.9e-58 198.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EIW84494.1 - 7.7e-11 41.5 1.2 3.1e-10 39.6 0.9 2.0 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EIW84494.1 - 0.072 12.7 2.4 2.1 8.0 0.0 3.9 4 1 0 5 5 5 0 Leucine Rich repeats (2 copies) F-box PF00646.28 EIW84494.1 - 0.22 11.2 7.4 0.052 13.2 1.3 2.9 3 1 0 3 3 3 0 F-box domain CDC27 PF09507.5 EIW84495.1 - 2.3e-33 116.0 92.7 2.2e-27 96.3 28.3 3.2 1 1 2 3 3 3 3 DNA polymerase subunit Cdc27 BAALC_N PF06989.7 EIW84495.1 - 8.5 6.7 7.1 0.87 9.9 0.7 2.3 2 0 0 2 2 2 0 BAALC N-terminus p450 PF00067.17 EIW84496.1 - 4.5e-79 266.1 0.0 5.1e-79 265.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EIW84497.1 - 6.5e-10 38.5 0.0 1.7e-09 37.2 0.0 1.7 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EIW84497.1 - 0.2 11.3 0.9 0.88 9.2 0.1 2.1 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 EIW84498.1 - 9.6e-10 38.0 0.0 3e-09 36.4 0.0 1.9 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIW84498.1 - 0.59 9.8 2.1 7.4 6.3 0.1 3.2 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Aminotran_1_2 PF00155.16 EIW84499.1 - 5.9e-25 87.9 0.0 7.4e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EIW84499.1 - 1.2e-09 37.2 0.0 1.8e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase p450 PF00067.17 EIW84500.1 - 5.7e-75 252.6 0.1 8.6e-75 252.0 0.1 1.2 1 0 0 1 1 1 1 Cytochrome P450 F-box-like PF12937.2 EIW84501.1 - 9.2e-09 34.9 0.3 1.9e-08 33.8 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW84501.1 - 0.00026 20.5 0.1 0.0013 18.2 0.0 2.0 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EIW84502.1 - 2.7e-10 39.7 3.3 1.6e-07 30.9 0.4 3.1 2 0 0 2 2 2 2 F-box-like Talin_middle PF09141.5 EIW84502.1 - 0.0046 16.6 1.1 0.0081 15.8 0.8 1.3 1 0 0 1 1 1 1 Talin, middle domain F-box PF00646.28 EIW84502.1 - 0.0071 15.9 2.5 2.4 7.8 0.0 3.8 3 0 0 3 3 3 1 F-box domain NPV_P10 PF05531.7 EIW84502.1 - 0.012 15.8 1.6 0.63 10.3 0.5 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein F-box-like_2 PF13013.1 EIW84502.1 - 0.033 13.9 0.6 0.78 9.4 0.0 2.4 2 0 0 2 2 2 0 F-box-like domain Reo_sigmaC PF04582.7 EIW84502.1 - 0.054 12.6 1.7 0.12 11.5 1.2 1.6 1 0 0 1 1 1 0 Reovirus sigma C capsid protein p450 PF00067.17 EIW84503.1 - 1.6e-72 244.5 0.0 2.1e-71 240.8 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 EIW84504.1 - 2.5e-13 49.6 0.0 4.6e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW84504.1 - 1e-10 41.3 0.0 2.3e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EIW84504.1 - 0.00012 22.9 0.0 0.00019 22.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase p450 PF00067.17 EIW84505.1 - 0.00012 20.7 0.0 0.00012 20.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW84507.1 - 5.1e-74 249.4 0.0 6.9e-74 249.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Trm56 PF01994.11 EIW84507.1 - 0.14 11.8 0.0 7.1 6.4 0.0 2.6 3 0 0 3 3 3 0 tRNA ribose 2'-O-methyltransferase, aTrm56 GMP_synt_C PF00958.17 EIW84508.1 - 1.1e-40 137.2 0.1 2.1e-40 136.3 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.23 EIW84508.1 - 6e-37 126.9 0.0 1e-36 126.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EIW84508.1 - 1.7e-10 40.7 0.0 3.2e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase C26 NAD_synthase PF02540.12 EIW84508.1 - 1.8e-10 40.1 0.1 1.1e-06 27.7 0.0 2.2 2 0 0 2 2 2 2 NAD synthase ThiI PF02568.9 EIW84508.1 - 0.0028 17.1 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.11 EIW84508.1 - 0.0031 16.1 0.1 0.0052 15.3 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.16 EIW84508.1 - 0.0044 16.5 0.0 0.0073 15.8 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EIW84508.1 - 0.0054 16.0 0.0 0.023 13.9 0.0 1.9 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Arginosuc_synth PF00764.14 EIW84508.1 - 0.026 13.5 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Arginosuccinate synthase ATP_bind_3 PF01171.15 EIW84508.1 - 0.05 13.1 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 PP-loop family SF-assemblin PF06705.6 EIW84508.1 - 0.11 11.5 0.2 0.19 10.8 0.2 1.3 1 0 0 1 1 1 0 SF-assemblin/beta giardin DUF2392 PF10288.4 EIW84508.1 - 0.16 12.3 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) p450 PF00067.17 EIW84509.1 - 1e-51 175.9 0.0 1.8e-51 175.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW84510.1 - 0.00027 19.6 0.0 0.00029 19.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW84512.1 - 2.1e-18 66.1 0.1 2.4e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Slp PF03843.8 EIW84512.1 - 0.15 11.0 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein Slp family p450 PF00067.17 EIW84513.1 - 8.6e-75 252.0 0.0 1.1e-74 251.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ThylakoidFormat PF11264.3 EIW84513.1 - 0.08 12.5 0.1 11 5.5 0.0 2.2 2 0 0 2 2 2 0 Thylakoid formation protein Asp PF00026.18 EIW84515.1 - 7.6e-16 58.2 0.0 1.2e-14 54.2 0.0 2.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EIW84515.1 - 0.00093 19.6 0.1 0.19 12.2 0.0 3.2 3 1 0 3 3 3 1 Aspartyl protease DUF3453 PF11935.3 EIW84516.1 - 0.041 13.2 0.2 0.26 10.6 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3453) HGTP_anticodon PF03129.15 EIW84516.1 - 0.08 12.8 0.0 0.68 9.9 0.0 2.3 2 0 0 2 2 2 0 Anticodon binding domain V_ATPase_I PF01496.14 EIW84516.1 - 0.19 9.5 1.7 0.26 9.0 1.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Dec-1 PF04624.9 EIW84516.1 - 7.6 6.2 6.9 33 4.2 3.0 2.7 2 1 0 2 2 2 0 Dec-1 repeat LysE PF01810.13 EIW84517.1 - 0.13 11.4 11.3 0.016 14.5 4.5 2.0 2 1 0 2 2 2 0 LysE type translocator DUF2512 PF10710.4 EIW84517.1 - 2.7 7.4 12.7 0.27 10.6 4.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2512) Cytochrom_B_C PF00032.12 EIW84517.1 - 3.7 7.8 8.2 1.3 9.2 0.9 2.5 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DUF3436 PF11918.3 EIW84518.1 - 0.021 15.0 0.1 0.055 13.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3436) MFS_1 PF07690.11 EIW84519.1 - 1.9e-27 95.8 13.8 1.9e-27 95.8 9.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily F-box-like PF12937.2 EIW84520.1 - 1.9e-08 33.9 0.3 1.9e-08 33.9 0.2 2.1 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 EIW84520.1 - 0.00018 21.2 4.0 0.67 9.7 0.1 3.6 3 0 0 3 3 3 3 Leucine rich repeat F-box PF00646.28 EIW84520.1 - 0.21 11.2 3.8 0.13 11.9 0.5 2.3 3 0 0 3 3 3 0 F-box domain Epimerase PF01370.16 EIW84521.1 - 5.5e-18 65.2 0.0 7.8e-18 64.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW84521.1 - 4.3e-12 46.4 0.1 1.5e-11 44.6 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIW84521.1 - 2.9e-10 39.3 0.1 5.7e-10 38.3 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EIW84521.1 - 7.1e-07 28.3 0.0 2.5e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EIW84521.1 - 9.1e-07 28.3 0.1 1.8e-06 27.4 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EIW84521.1 - 1.6e-05 24.9 1.7 3e-05 23.9 0.2 2.1 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIW84521.1 - 3.2e-05 23.6 0.5 6.1e-05 22.7 0.4 1.5 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 EIW84521.1 - 0.014 14.2 1.3 0.098 11.5 0.0 2.2 2 0 0 2 2 2 0 RmlD substrate binding domain DUF2092 PF09865.4 EIW84521.1 - 0.12 11.4 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Predicted periplasmic protein (DUF2092) MFS_1 PF07690.11 EIW84522.1 - 1.9e-23 82.7 28.6 1.9e-23 82.7 19.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DsbC_N PF10411.4 EIW84522.1 - 0.032 13.4 0.0 0.083 12.1 0.0 1.7 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus FPN1 PF06963.7 EIW84522.1 - 0.1 10.9 6.4 0.017 13.5 1.0 2.1 2 1 0 2 2 2 0 Ferroportin1 (FPN1) EB PF01683.13 EIW84524.1 - 5 7.2 21.6 2.7 8.1 3.6 3.7 3 1 0 3 3 3 0 EB module F-box-like PF12937.2 EIW84525.1 - 1.8e-10 40.3 0.0 3.8e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW84525.1 - 0.00098 18.7 0.4 0.015 14.9 0.0 2.4 2 1 0 2 2 2 1 F-box domain p450 PF00067.17 EIW84526.1 - 3.1e-69 233.6 0.0 3.8e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transposase_21 PF02992.9 EIW84527.1 - 1.5e-09 37.2 0.0 3.3e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.1 EIW84527.1 - 0.00023 20.6 0.0 0.00043 19.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) CAF-1_p150 PF11600.3 EIW84528.1 - 0.035 13.4 8.0 0.045 13.1 5.6 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Adeno_terminal PF02459.10 EIW84528.1 - 0.041 12.0 2.5 0.041 12.0 1.7 1.1 1 0 0 1 1 1 0 Adenoviral DNA terminal protein SOBP PF15279.1 EIW84528.1 - 0.043 14.1 1.6 0.046 14.0 1.1 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein DUF2146 PF10220.4 EIW84528.1 - 1.7 6.5 6.0 2.1 6.2 4.1 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) MFS_1 PF07690.11 EIW84530.1 - 4.8e-34 117.6 35.9 4.8e-34 117.6 24.9 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 EIW84531.1 - 2.1e-37 128.6 27.2 2.1e-37 128.6 18.9 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily 2TM PF13239.1 EIW84531.1 - 2.7 8.1 7.6 19 5.3 0.5 4.2 4 0 0 4 4 4 0 2TM domain F-box-like PF12937.2 EIW84532.1 - 2.3e-12 46.4 0.8 6.1e-12 45.0 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIW84532.1 - 0.016 14.8 0.9 0.69 9.6 0.1 3.3 3 0 0 3 3 3 0 F-box domain BAH PF01426.13 EIW84533.1 - 1.7e-07 30.9 0.0 2.8e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 BAH domain adh_short PF00106.20 EIW84534.1 - 1.7e-25 89.8 0.3 2.2e-25 89.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW84534.1 - 1.2e-15 57.9 0.0 1.5e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW84534.1 - 6.5e-11 42.2 0.1 1e-10 41.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW84534.1 - 0.00042 19.8 0.0 0.00079 18.9 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW84534.1 - 0.00049 20.1 0.1 0.0007 19.6 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EIW84534.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain adh_short PF00106.20 EIW84535.1 - 3.4e-30 105.1 0.6 5.2e-30 104.5 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW84535.1 - 1.1e-14 54.8 0.0 1.5e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW84535.1 - 1.5e-13 50.8 0.1 2.3e-13 50.1 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIW84535.1 - 3.1e-06 27.3 0.2 4.2e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW84535.1 - 3.3e-05 23.4 0.0 5.4e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EIW84535.1 - 0.0036 17.0 0.1 0.0076 16.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 EIW84535.1 - 0.024 13.5 0.1 0.035 13.0 0.1 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain Dala_Dala_lig_C PF07478.8 EIW84535.1 - 0.031 13.6 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus NmrA PF05368.8 EIW84535.1 - 0.037 13.2 0.2 0.42 9.8 0.1 2.1 2 0 0 2 2 2 0 NmrA-like family AAA PF00004.24 EIW84536.1 - 6.7e-13 48.9 0.0 1.2e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIW84536.1 - 2.1e-12 47.4 0.0 2e-11 44.2 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain BAH PF01426.13 EIW84536.1 - 9.9e-10 38.2 0.0 1.9e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 BAH domain AAA_22 PF13401.1 EIW84536.1 - 5.8e-09 36.1 0.0 2e-08 34.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIW84536.1 - 0.0001 22.0 0.1 0.00041 20.0 0.0 2.1 1 0 0 1 1 1 1 Part of AAA domain DUF2075 PF09848.4 EIW84536.1 - 0.00019 20.5 0.1 0.00049 19.1 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 EIW84536.1 - 0.0037 16.9 0.0 0.01 15.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_17 PF13207.1 EIW84536.1 - 0.0073 17.1 0.2 0.087 13.6 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 EIW84536.1 - 0.011 15.2 0.1 0.028 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 EIW84536.1 - 0.07 11.8 0.1 0.28 9.8 0.0 1.8 2 0 0 2 2 2 0 TIP49 C-terminus NTPase_1 PF03266.10 EIW84536.1 - 0.093 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 NTPase PIF1 PF05970.9 EIW84536.1 - 0.28 10.0 0.0 0.48 9.3 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase adh_short PF00106.20 EIW84537.1 - 8.8e-24 84.3 0.6 1.1e-23 83.9 0.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW84537.1 - 7.1e-09 35.7 0.0 1e-08 35.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW84537.1 - 1.6e-07 31.2 0.1 2.5e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EIW84537.1 - 7.2e-07 29.3 0.1 9.6e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW84537.1 - 0.00056 19.4 0.0 0.00092 18.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIW84537.1 - 0.053 12.3 0.0 0.078 11.8 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain ICMT PF04140.9 EIW84539.1 - 1.7e-09 37.7 0.2 3.8e-09 36.6 0.0 1.6 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIW84539.1 - 7.6e-07 29.2 0.8 7.4e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase F-box-like PF12937.2 EIW84540.1 - 1.3e-10 40.7 0.0 3.2e-10 39.5 0.0 1.7 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EIW84540.1 - 0.038 13.6 0.1 0.23 11.1 0.1 2.2 1 1 0 1 1 1 0 F-box domain DUF4218 PF13960.1 EIW84541.1 - 7e-05 22.2 0.0 0.00017 21.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Transposase_21 PF02992.9 EIW84541.1 - 0.0074 15.3 1.1 0.026 13.6 0.0 2.0 2 0 0 2 2 2 1 Transposase family tnp2 DUF4616 PF15394.1 EIW84542.1 - 0.00093 18.3 0.1 0.00093 18.3 0.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4616) Lipase_GDSL_2 PF13472.1 EIW84544.1 - 7.4e-11 42.4 0.0 2e-10 41.0 0.0 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family GST_N_3 PF13417.1 EIW84545.1 - 1.1e-12 48.0 0.1 3.4e-12 46.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW84545.1 - 4.6e-07 29.6 0.1 7.9e-07 28.8 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW84545.1 - 7.2e-07 29.1 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW84545.1 - 8e-05 22.5 0.0 0.00014 21.7 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW84545.1 - 0.00012 22.1 0.0 0.00046 20.3 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Exonuc_VII_L PF02601.10 EIW84546.1 - 4.6 6.3 12.4 9.9 5.2 8.6 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit F-box-like PF12937.2 EIW84550.1 - 1.6e-08 34.1 0.0 6.3e-08 32.2 0.0 2.1 1 1 0 1 1 1 1 F-box-like IDO PF01231.13 EIW84551.1 - 1.1e-95 320.6 0.0 5.8e-62 209.4 0.0 2.2 2 0 0 2 2 2 2 Indoleamine 2,3-dioxygenase DUF1680 PF07944.7 EIW84552.1 - 1.2e-23 83.1 0.0 5.2e-23 81.1 0.0 1.7 1 1 1 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) SHR3_chaperone PF08229.6 EIW84553.1 - 0.033 13.1 0.8 0.033 13.1 0.5 2.1 2 1 1 3 3 3 0 ER membrane protein SH3 IDO PF01231.13 EIW84554.1 - 5e-102 341.4 0.0 5.9e-66 222.6 0.0 2.1 2 0 0 2 2 2 2 Indoleamine 2,3-dioxygenase ATP-synt_B PF00430.13 EIW84554.1 - 0.3 10.8 2.2 0.6 9.9 1.5 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) LRR_4 PF12799.2 EIW84555.1 - 6.6 6.4 6.2 3.5 7.3 0.7 2.8 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Glyco_hydro_16 PF00722.16 EIW84558.1 - 4.3e-07 29.3 0.8 9.4e-07 28.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Ribosomal_L40e PF01020.12 EIW84559.1 - 0.22 11.1 1.8 0.23 11.0 0.1 1.9 2 0 0 2 2 2 0 Ribosomal L40e family Epimerase PF01370.16 EIW84560.1 - 1.2e-12 47.7 0.4 2.6e-12 46.6 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW84560.1 - 1.5e-11 44.6 0.3 4.5e-11 43.0 0.2 1.9 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EIW84560.1 - 4e-07 29.0 0.2 9.4e-07 27.8 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EIW84560.1 - 2e-06 27.2 0.3 4.6e-06 26.0 0.1 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EIW84560.1 - 0.0002 20.3 0.2 0.00052 19.0 0.1 1.7 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EIW84560.1 - 0.0063 16.4 2.9 0.013 15.4 0.7 2.6 2 1 0 2 2 2 1 short chain dehydrogenase PPI_Ypi1 PF07491.6 EIW84562.1 - 7.8e-27 92.6 0.3 1.4e-26 91.9 0.2 1.4 1 0 0 1 1 1 1 Protein phosphatase inhibitor zf-MYND PF01753.13 EIW84563.1 - 2.8e-11 43.0 8.5 2.8e-11 43.0 5.9 2.2 2 0 0 2 2 2 1 MYND finger p450 PF00067.17 EIW84564.1 - 1.7e-73 247.7 0.0 2.2e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RicinB_lectin_2 PF14200.1 EIW84565.1 - 3.2e-05 24.2 0.1 0.00095 19.5 0.0 1.8 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.17 EIW84565.1 - 0.053 13.5 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Ricin-type beta-trefoil lectin domain DUF951 PF06107.6 EIW84565.1 - 0.11 12.0 0.1 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) DDE_3 PF13358.1 EIW84566.1 - 3.5e-08 33.3 0.0 7.3e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease MIS13 PF08202.6 EIW84568.1 - 1.1e-21 77.2 4.6 3.1e-21 75.7 3.2 1.7 1 1 0 1 1 1 1 Mis12-Mtw1 protein family p450 PF00067.17 EIW84569.1 - 3.1e-65 220.4 0.0 4.4e-65 220.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_13 PF08421.6 EIW84569.1 - 0.057 12.9 0.1 0.18 11.3 0.0 1.9 2 0 0 2 2 2 0 Putative zinc binding domain zf-DHHC PF01529.15 EIW84570.1 - 1.1e-28 99.7 10.2 1.1e-28 99.7 7.1 1.9 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF4131 PF13567.1 EIW84570.1 - 1.9 7.8 4.9 9.7 5.5 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) F-box-like PF12937.2 EIW84571.1 - 2.4e-06 27.1 0.8 7.1e-06 25.6 0.6 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EIW84571.1 - 0.41 10.3 3.5 1 9.1 0.1 2.8 3 0 0 3 3 3 0 F-box domain F-box-like PF12937.2 EIW84572.1 - 4.6e-09 35.8 0.8 1.3e-08 34.4 0.6 1.8 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EIW84572.1 - 0.023 14.3 0.8 0.16 11.6 0.6 2.2 1 1 0 1 1 1 0 F-box-like domain F-box PF00646.28 EIW84572.1 - 0.043 13.4 0.4 0.23 11.1 0.3 2.2 1 1 0 1 1 1 0 F-box domain PPARgamma_N PF12577.3 EIW84572.1 - 0.31 11.3 2.2 1.3 9.3 0.0 2.7 3 1 0 3 3 3 0 PPAR gamma N-terminal region FYDLN_acid PF09538.5 EIW84573.1 - 1.4 9.5 7.6 4.6 7.8 5.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) F-box-like PF12937.2 EIW84575.1 - 6.8e-13 48.1 0.6 2.1e-12 46.5 0.4 1.9 1 0 0 1 1 1 1 F-box-like Sugar_tr PF00083.19 EIW84576.1 - 8.8e-85 284.9 24.8 1e-84 284.7 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW84576.1 - 7.8e-18 64.2 49.4 4.4e-13 48.6 18.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EIW84576.1 - 0.0012 17.1 4.9 0.0012 17.1 3.4 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) DUF554 PF04474.7 EIW84576.1 - 0.014 14.6 3.0 0.028 13.5 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF554) DUF1228 PF06779.9 EIW84576.1 - 1.7 8.6 11.8 0.089 12.8 0.6 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF1228) GST_C PF00043.20 EIW84577.1 - 2.2e-16 59.6 0.0 3.7e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW84577.1 - 2.8e-11 43.4 0.0 5.6e-11 42.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EIW84577.1 - 2e-09 37.5 0.0 3.4e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW84577.1 - 1.5e-08 34.4 0.1 2.9e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW84577.1 - 3.8e-06 27.3 0.1 5.4e-06 26.8 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW84577.1 - 3.4e-05 23.7 0.0 6.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain F-box-like PF12937.2 EIW84579.1 - 3e-11 42.8 0.0 6.6e-11 41.7 0.0 1.6 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EIW84579.1 - 0.013 15.1 3.5 0.8 9.4 0.0 2.9 2 1 1 3 3 3 0 F-box domain p450 PF00067.17 EIW84580.1 - 4.8e-70 236.3 0.0 9e-70 235.4 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 O-FucT PF10250.4 EIW84581.1 - 0.0018 17.4 0.0 0.39 9.7 0.0 2.2 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase S10_plectin PF03501.10 EIW84582.1 - 1e-43 147.0 0.2 1.2e-43 146.8 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.14 EIW84582.1 - 0.0044 16.7 0.0 0.0072 16.0 0.0 1.5 1 1 0 1 1 1 1 Sugar-specific transcriptional regulator TrmB p450 PF00067.17 EIW84584.1 - 3.2e-74 250.1 0.1 4.6e-74 249.6 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW84585.1 - 5.1e-76 256.0 0.0 6.6e-76 255.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EIW84586.1 - 2.7e-34 118.2 0.0 4e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW84586.1 - 3.8e-08 33.0 11.9 7.3e-08 32.1 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 EIW84586.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Gal4-like dimerisation domain Fungal_trans PF04082.13 EIW84587.1 - 1.4e-29 102.7 0.0 2.5e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW84587.1 - 2.8e-08 33.5 10.1 5.2e-08 32.6 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 EIW84587.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain Fungal_trans PF04082.13 EIW84588.1 - 4.9e-21 74.7 0.0 5.3e-17 61.5 0.0 2.0 2 0 0 2 2 2 2 Fungal specific transcription factor domain PET PF06297.9 EIW84589.1 - 0.14 11.7 1.0 1.1 8.9 0.5 2.1 2 0 0 2 2 2 0 PET Domain DUF3735 PF12537.3 EIW84590.1 - 0.023 14.7 1.3 0.28 11.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3735) PepSY_TM_2 PF13703.1 EIW84590.1 - 6.4 7.0 12.7 1.1 9.4 4.2 3.0 2 1 1 3 3 3 0 PepSY-associated TM helix Aldo_ket_red PF00248.16 EIW84591.1 - 1.7e-45 155.0 0.0 1.9e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 EIW84592.1 - 1.6e-31 109.1 0.3 2.9e-31 108.3 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW84592.1 - 7e-10 38.6 7.9 1.3e-09 37.7 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 EIW84592.1 - 0.047 13.6 0.1 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Gal4-like dimerisation domain F-box-like PF12937.2 EIW84593.1 - 3.3e-06 26.7 1.2 8.2e-06 25.4 0.1 2.3 2 0 0 2 2 2 1 F-box-like OST-HTH PF12872.2 EIW84594.1 - 0.12 12.1 0.0 0.38 10.6 0.0 1.8 2 0 0 2 2 2 0 OST-HTH/LOTUS domain TFIIF_beta PF02270.10 EIW84595.1 - 3.8e-50 171.2 0.0 5e-50 170.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit GST_N_3 PF13417.1 EIW84596.1 - 6.6e-17 61.5 0.0 1.1e-16 60.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EIW84596.1 - 1e-16 60.8 0.0 2.4e-16 59.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW84596.1 - 3.6e-12 46.0 0.0 4.5e-12 45.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW84596.1 - 5.3e-11 42.3 0.0 8.9e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW84596.1 - 1.7e-06 27.7 0.0 2.3e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW84596.1 - 0.0002 21.7 0.0 0.00028 21.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain F-box-like PF12937.2 EIW84597.1 - 1.2e-09 37.7 0.1 3.9e-09 36.0 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW84597.1 - 0.017 14.7 0.2 0.13 11.9 0.1 2.4 1 1 0 1 1 1 0 F-box domain Fungal_trans PF04082.13 EIW84598.1 - 1e-29 103.2 0.0 1.8e-29 102.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW84598.1 - 1.1e-06 28.4 7.0 2.1e-06 27.5 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 EIW84598.1 - 0.0067 16.3 0.1 0.014 15.3 0.1 1.4 1 0 0 1 1 1 1 Gal4-like dimerisation domain Fungal_trans PF04082.13 EIW84600.1 - 3e-28 98.4 0.0 6.3e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW84600.1 - 6.9e-06 25.8 8.9 1.4e-05 24.9 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 EIW84600.1 - 0.058 13.3 0.1 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Gal4-like dimerisation domain PapG_C PF03628.8 EIW84601.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 PapG chaperone-binding domain DUF1752 PF08550.5 EIW84602.1 - 1.1e-14 53.6 1.6 1.4e-14 53.3 1.1 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) DUF3295 PF11702.3 EIW84603.1 - 2.3e-11 43.3 3.7 2.3e-11 43.3 2.6 5.2 2 1 2 5 5 5 1 Protein of unknown function (DUF3295) F-box-like PF12937.2 EIW84604.1 - 4.5e-09 35.8 0.1 1.2e-08 34.5 0.1 1.7 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EIW84604.1 - 0.011 15.3 0.6 0.16 11.6 0.4 2.2 1 1 0 1 1 1 0 F-box domain Fungal_trans PF04082.13 EIW84605.1 - 8.6e-31 106.7 0.0 1.8e-30 105.7 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW84605.1 - 0.0012 18.7 5.8 0.0025 17.6 4.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SOG2 PF10428.4 EIW84605.1 - 0.089 11.4 3.5 0.19 10.3 2.4 1.5 1 0 0 1 1 1 0 RAM signalling pathway protein Fungal_trans PF04082.13 EIW84606.1 - 1.7e-31 109.0 0.0 3.9e-31 107.8 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW84606.1 - 6.4e-06 25.9 8.9 1.4e-05 24.9 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 EIW84606.1 - 0.058 13.3 0.1 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Gal4-like dimerisation domain F-box-like PF12937.2 EIW84607.1 - 1.2e-09 37.7 0.0 3.6e-09 36.2 0.0 1.9 1 1 0 1 1 1 1 F-box-like STE3 PF02076.10 EIW84608.1 - 1.1e-102 342.9 11.1 1.3e-102 342.7 7.7 1.0 1 0 0 1 1 1 1 Pheromone A receptor Aldose_epim PF01263.15 EIW84609.1 - 3.5e-20 72.3 1.8 1.2e-18 67.2 1.2 2.9 1 1 0 1 1 1 1 Aldose 1-epimerase GHMP_kinases_C PF08544.8 EIW84610.1 - 1.5e-14 53.8 0.4 5.1e-12 45.8 0.0 3.4 2 1 1 3 3 3 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 EIW84610.1 - 9.6e-14 50.4 0.1 1.9e-13 49.4 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 EIW84610.1 - 4.2e-12 45.9 2.0 1.3e-11 44.4 1.4 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain Activator-TraM PF11657.3 EIW84610.1 - 0.11 11.9 0.0 0.31 10.5 0.0 1.7 1 0 0 1 1 1 0 Transcriptional activator TraM Glyco_hydro_10 PF00331.15 EIW84611.1 - 2.4e-91 306.1 0.0 2.9e-91 305.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Pro-kuma_activ PF09286.6 EIW84612.1 - 2.9e-25 88.9 0.3 1e-22 80.7 0.2 2.4 1 1 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EIW84612.1 - 2.7e-06 26.7 1.7 4.7e-06 25.9 1.1 1.4 1 1 0 1 1 1 1 Subtilase family MBOAT_2 PF13813.1 EIW84613.1 - 5.6e-16 58.4 2.1 5.6e-16 58.4 1.4 2.7 3 0 0 3 3 3 1 Membrane bound O-acyl transferase family YlaC PF10777.4 EIW84613.1 - 0.089 12.3 1.3 0.16 11.5 0.9 1.3 1 0 0 1 1 1 0 Inner membrane protein YlaC IMS_C PF11799.3 EIW84614.1 - 0.035 14.0 0.0 0.086 12.7 0.0 1.7 1 0 0 1 1 1 0 impB/mucB/samB family C-terminal domain Oxidored_molyb PF00174.14 EIW84615.1 - 7.9e-48 162.0 0.0 1.2e-47 161.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EIW84615.1 - 2.1e-46 156.7 0.0 3.5e-46 156.0 0.0 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.19 EIW84615.1 - 1.9e-26 92.0 0.0 3.6e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EIW84615.1 - 4.1e-21 75.6 0.0 8.5e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.23 EIW84615.1 - 4.1e-20 71.3 0.0 1.5e-19 69.5 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 EIW84615.1 - 0.014 15.2 0.0 0.35 10.7 0.0 2.2 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Prefoldin_2 PF01920.15 EIW84616.1 - 3.6e-21 74.9 9.1 4.6e-21 74.5 6.3 1.2 1 0 0 1 1 1 1 Prefoldin subunit CENP-F_leu_zip PF10473.4 EIW84616.1 - 0.00052 19.8 9.8 0.022 14.6 3.2 2.1 2 0 0 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_3 PF13758.1 EIW84616.1 - 0.002 17.8 0.5 0.0034 17.1 0.3 1.4 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 EIW84616.1 - 0.0043 16.7 2.1 0.0043 16.7 1.4 2.3 2 1 1 3 3 3 1 Prefoldin subunit Leu_zip PF15294.1 EIW84616.1 - 0.006 15.7 5.2 0.007 15.5 3.6 1.0 1 0 0 1 1 1 1 Leucine zipper DUF2702 PF10863.3 EIW84616.1 - 0.0066 16.1 3.9 0.0085 15.8 2.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2702) Macoilin PF09726.4 EIW84616.1 - 0.023 12.9 5.9 0.027 12.7 4.1 1.0 1 0 0 1 1 1 0 Transmembrane protein Occludin_ELL PF07303.8 EIW84616.1 - 0.027 15.2 4.4 0.26 12.0 0.2 2.1 1 1 1 2 2 2 0 Occludin homology domain DUF641 PF04859.7 EIW84616.1 - 0.032 13.9 6.0 0.072 12.8 1.6 2.1 1 1 0 2 2 2 0 Plant protein of unknown function (DUF641) CO_dh PF02552.11 EIW84616.1 - 0.036 13.6 0.6 0.049 13.1 0.4 1.1 1 0 0 1 1 1 0 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit TcdA_TcdB PF12919.2 EIW84616.1 - 0.041 12.3 2.1 0.048 12.1 1.5 1.1 1 0 0 1 1 1 0 TcdA/TcdB catalytic glycosyltransferase domain DUF2046 PF09755.4 EIW84616.1 - 0.045 12.6 2.8 0.28 10.0 0.5 2.1 1 1 0 2 2 2 0 Uncharacterized conserved protein H4 (DUF2046) Poty_PP PF08440.5 EIW84616.1 - 0.055 12.5 2.8 0.068 12.2 1.9 1.0 1 0 0 1 1 1 0 Potyviridae polyprotein IncA PF04156.9 EIW84616.1 - 0.064 12.8 7.6 0.11 12.1 5.3 1.4 1 1 0 1 1 1 0 IncA protein FadA PF09403.5 EIW84616.1 - 0.1 12.5 6.3 1.4 8.8 0.2 2.7 2 1 0 2 2 2 0 Adhesion protein FadA NPV_P10 PF05531.7 EIW84616.1 - 0.11 12.7 6.5 0.76 10.0 0.9 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Foie-gras_1 PF11817.3 EIW84616.1 - 0.12 11.8 1.1 0.22 10.9 0.7 1.4 1 1 0 1 1 1 0 Foie gras liver health family 1 Spc7 PF08317.6 EIW84616.1 - 0.13 10.8 6.8 0.15 10.6 4.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4201 PF13870.1 EIW84616.1 - 0.15 11.4 5.8 0.14 11.6 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF1192 PF06698.6 EIW84616.1 - 0.16 11.8 0.9 0.54 10.1 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1192) Tropomyosin_1 PF12718.2 EIW84616.1 - 0.17 11.7 9.2 0.19 11.5 1.7 2.3 2 0 0 2 2 2 0 Tropomyosin like ATG16 PF08614.6 EIW84616.1 - 0.31 10.8 8.0 1.7 8.3 1.3 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) ERp29 PF07749.7 EIW84616.1 - 0.31 11.6 2.6 0.65 10.6 1.8 1.8 1 1 0 1 1 1 0 Endoplasmic reticulum protein ERp29, C-terminal domain Atg14 PF10186.4 EIW84616.1 - 0.33 9.8 4.4 0.38 9.6 3.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 ADIP PF11559.3 EIW84616.1 - 0.47 10.3 7.8 0.21 11.4 1.1 2.2 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding WEMBL PF05701.6 EIW84616.1 - 0.54 8.6 9.9 2 6.8 5.5 1.9 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Syntaxin_2 PF14523.1 EIW84616.1 - 0.75 9.8 7.9 80 3.3 5.5 2.3 1 1 0 1 1 1 0 Syntaxin-like protein APG6 PF04111.7 EIW84616.1 - 1.1 8.2 10.2 1.5 7.7 5.8 1.8 1 1 1 2 2 2 0 Autophagy protein Apg6 Rootletin PF15035.1 EIW84616.1 - 1.2 9.1 8.4 14 5.5 5.9 2.2 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Fez1 PF06818.10 EIW84616.1 - 1.5 8.7 8.1 0.9 9.5 1.8 2.0 1 1 1 2 2 2 0 Fez1 Spc24 PF08286.6 EIW84616.1 - 1.6 8.4 8.4 7.7 6.2 0.3 2.1 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 PspA_IM30 PF04012.7 EIW84616.1 - 2.1 7.6 11.4 0.61 9.4 1.8 2.0 2 0 0 2 2 2 0 PspA/IM30 family TPR_MLP1_2 PF07926.7 EIW84616.1 - 2.9 7.6 11.7 5.3 6.8 1.6 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF972 PF06156.8 EIW84616.1 - 4.7 7.6 7.5 22 5.4 0.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF972) Seryl_tRNA_N PF02403.17 EIW84616.1 - 5.8 6.9 8.7 23 5.0 0.4 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Phage_GP20 PF06810.6 EIW84616.1 - 6.2 6.2 10.3 9.4 5.6 0.5 2.1 1 1 0 2 2 2 0 Phage minor structural protein GP20 TMF_DNA_bd PF12329.3 EIW84616.1 - 6.5 6.6 11.2 5.4 6.9 2.2 2.3 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Mnd1 PF03962.10 EIW84616.1 - 6.8 6.3 9.2 8.8 5.9 2.3 2.0 1 1 0 1 1 1 0 Mnd1 family DivIVA PF05103.8 EIW84616.1 - 7.9 6.5 11.2 7.1 6.6 2.2 2.1 1 1 1 2 2 2 0 DivIVA protein Amidohydro_4 PF13147.1 EIW84617.1 - 1.3e-16 61.4 4.0 1.3e-16 61.4 2.8 3.0 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_5 PF13594.1 EIW84617.1 - 3.8e-13 49.0 0.2 3.5e-08 33.1 0.0 2.7 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EIW84617.1 - 4.6e-09 36.3 0.0 1.7e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.6 EIW84617.1 - 4e-05 23.0 2.9 0.0016 17.7 0.2 2.6 2 1 0 2 2 2 2 Amidohydrolase family LRR_8 PF13855.1 EIW84618.1 - 0.088 12.5 8.4 0.12 12.1 0.1 4.6 4 1 0 5 5 5 0 Leucine rich repeat LRR_4 PF12799.2 EIW84618.1 - 2.5 7.8 11.5 7.2 6.3 0.2 4.9 3 3 1 4 4 4 0 Leucine Rich repeats (2 copies) 7tm_7 PF08395.7 EIW84619.1 - 1.8 7.5 17.0 2.4 7.0 6.9 2.3 2 0 0 2 2 2 0 7tm Chemosensory receptor LRR_4 PF12799.2 EIW84620.1 - 1.1 8.9 5.7 29 4.4 0.0 4.9 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) Glyco_hydro_1 PF00232.13 EIW84621.1 - 1.9e-108 362.5 1.2 8.2e-107 357.2 0.8 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 zf-RING_2 PF13639.1 EIW84622.1 - 8.8e-08 31.8 3.7 2.2e-07 30.5 2.6 1.7 1 0 0 1 1 1 1 Ring finger domain SWIM PF04434.12 EIW84622.1 - 1.1e-06 27.9 0.3 2.1e-06 27.0 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger FANCL_C PF11793.3 EIW84622.1 - 3.1e-06 27.0 4.7 3.4e-05 23.7 2.0 2.2 2 0 0 2 2 2 1 FANCL C-terminal domain zf-rbx1 PF12678.2 EIW84622.1 - 0.0011 18.9 0.5 0.0029 17.6 0.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger C1_1 PF00130.17 EIW84622.1 - 0.0031 17.1 1.3 0.0031 17.1 0.9 2.4 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD PF00628.24 EIW84622.1 - 0.0059 16.2 5.1 0.012 15.2 3.6 1.6 1 0 0 1 1 1 1 PHD-finger DUF164 PF02591.10 EIW84622.1 - 0.092 12.5 0.8 0.21 11.4 0.5 1.5 1 0 0 1 1 1 0 Putative zinc ribbon domain zf-PHD-like PF15446.1 EIW84622.1 - 0.41 9.9 4.3 0.79 8.9 3.0 1.5 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain zf-C3HC4_2 PF13923.1 EIW84622.1 - 0.67 10.0 7.8 0.099 12.6 2.5 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW84622.1 - 5.4 6.8 8.3 0.42 10.3 2.1 1.9 2 0 0 2 2 2 0 zinc-RING finger domain Alph_Pro_TM PF09608.5 EIW84624.1 - 0.0014 18.1 0.8 0.0022 17.5 0.6 1.3 1 0 0 1 1 1 1 Putative transmembrane protein (Alph_Pro_TM) Pox_A14 PF05767.7 EIW84624.1 - 0.061 13.2 0.6 0.061 13.2 0.4 3.0 2 1 1 3 3 3 0 Poxvirus virion envelope protein A14 Adenylsucc_synt PF00709.16 EIW84625.1 - 2.7e-160 533.6 0.0 3e-160 533.4 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Amidohydro_4 PF13147.1 EIW84626.1 - 6e-30 105.2 9.5 8.3e-30 104.7 6.6 1.2 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EIW84626.1 - 5.1e-16 59.2 0.5 3.2e-08 33.6 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EIW84626.1 - 1.7e-11 43.7 0.8 1e-10 41.2 0.3 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EIW84626.1 - 1.9e-11 43.8 16.6 1e-10 41.4 6.7 2.3 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EIW84627.1 - 1.7e-13 51.2 0.9 2.1e-13 50.9 0.6 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EIW84627.1 - 3.8e-11 42.6 1.2 1.1e-10 41.2 0.8 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EIW84627.1 - 5.4e-06 26.2 0.1 6.6e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EIW84627.1 - 0.093 11.9 5.0 0.55 9.3 3.5 2.0 1 1 0 1 1 1 0 Amidohydrolase family Piwi PF02171.12 EIW84628.1 - 4.4e-74 249.1 0.0 8.2e-74 248.2 0.0 1.4 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EIW84628.1 - 1.4e-13 49.9 0.0 2.9e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EIW84628.1 - 6.7e-12 44.8 0.0 1.4e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 PAZ domain LSM14 PF12701.2 EIW84629.1 - 8.8e-27 92.7 0.0 1.4e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EIW84629.1 - 4.6e-09 36.7 1.0 9.2e-09 35.7 0.7 1.5 1 1 0 1 1 1 1 FDF domain SM-ATX PF14438.1 EIW84629.1 - 0.003 17.4 0.0 0.0047 16.8 0.0 1.3 1 0 0 1 1 1 1 Ataxin 2 SM domain Hist_deacetyl PF00850.14 EIW84630.1 - 0.0046 16.2 0.0 0.0071 15.6 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain LRR_8 PF13855.1 EIW84630.1 - 0.017 14.8 1.8 0.81 9.4 0.2 3.5 2 1 2 4 4 4 0 Leucine rich repeat FAD_binding_3 PF01494.14 EIW84631.1 - 3.1e-60 204.1 0.0 5.2e-59 200.0 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EIW84631.1 - 0.00028 20.0 0.1 0.0005 19.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EIW84631.1 - 0.0009 17.8 0.1 0.0014 17.2 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.1 EIW84631.1 - 0.0011 18.9 0.1 0.0042 17.0 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EIW84631.1 - 0.0011 17.7 0.4 0.13 10.8 0.1 2.3 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.1 EIW84631.1 - 0.0014 18.7 0.2 0.056 13.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW84631.1 - 0.0017 17.2 1.3 0.0029 16.5 0.2 1.9 2 1 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EIW84631.1 - 0.0038 16.3 0.1 0.011 14.7 0.1 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EIW84631.1 - 0.0047 15.8 0.8 0.015 14.2 0.4 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW84631.1 - 0.0096 16.3 0.1 0.48 10.8 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW84631.1 - 0.023 14.5 0.0 0.078 12.8 0.0 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EIW84632.1 - 1.5e-57 195.2 0.0 2.4e-57 194.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain F-box-like PF12937.2 EIW84634.1 - 8e-11 41.4 0.4 1.7e-10 40.4 0.3 1.6 1 0 0 1 1 1 1 F-box-like Ricin_B_lectin PF00652.17 EIW84635.1 - 7.3e-07 29.2 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain FAD_binding_3 PF01494.14 EIW84636.1 - 7.6e-76 255.4 0.0 1e-75 255.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIW84636.1 - 7.3e-07 28.4 0.9 0.00025 20.0 0.1 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 EIW84636.1 - 3.8e-06 26.1 0.2 4e-05 22.8 0.0 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EIW84636.1 - 3.8e-05 23.6 0.2 0.0002 21.2 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIW84636.1 - 0.00011 22.5 0.2 0.045 14.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EIW84636.1 - 0.00014 20.6 0.2 0.008 14.8 0.0 2.1 1 1 1 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EIW84636.1 - 0.00016 21.6 0.1 0.00039 20.3 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW84636.1 - 0.00018 20.1 0.5 0.00061 18.3 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EIW84636.1 - 0.00045 19.4 0.2 0.0094 15.0 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW84636.1 - 0.0012 17.8 0.3 0.0012 17.8 0.2 1.9 3 0 0 3 3 3 1 FAD binding domain NAD_binding_7 PF13241.1 EIW84636.1 - 0.0023 18.1 0.0 0.2 11.9 0.0 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Pyr_redox_3 PF13738.1 EIW84636.1 - 0.0036 17.4 0.2 0.011 15.8 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIW84636.1 - 0.022 14.5 0.5 0.059 13.1 0.1 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 EIW84636.1 - 0.067 12.0 0.1 0.1 11.4 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EIW84636.1 - 0.084 11.7 0.4 0.24 10.3 0.1 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Tom37_C PF11801.3 EIW84637.1 - 3.5 7.4 5.7 6.5 6.5 3.9 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain G6PD_bact PF10786.4 EIW84638.1 - 0.24 10.8 3.3 4.6 6.6 0.0 2.9 2 1 0 3 3 3 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) Coa1 PF08695.5 EIW84639.1 - 7.1e-30 102.9 0.0 1.1e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 His_Phos_2 PF00328.17 EIW84640.1 - 2e-37 129.3 0.0 2.4e-37 129.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Piwi PF02171.12 EIW84641.1 - 4.7e-82 275.3 0.0 7.1e-82 274.7 0.0 1.3 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EIW84641.1 - 8.1e-16 57.1 0.0 1.6e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EIW84641.1 - 3.2e-14 52.3 0.0 6.1e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Alpha-L-AF_C PF06964.7 EIW84641.1 - 0.0098 15.6 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus ABC_tran PF00005.22 EIW84644.1 - 1.7e-24 86.6 0.0 2.8e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIW84644.1 - 1.2e-07 31.9 0.0 2.8e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EIW84644.1 - 2.8e-06 26.7 0.1 0.058 12.6 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EIW84644.1 - 2.5e-05 23.7 0.1 0.00073 19.0 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EIW84644.1 - 0.00025 21.8 0.0 0.00049 20.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW84644.1 - 0.00026 21.0 0.4 0.0012 18.8 0.3 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.1 EIW84644.1 - 0.00051 20.4 0.0 0.00097 19.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain ABC_ATPase PF09818.4 EIW84644.1 - 0.0006 18.5 0.0 0.049 12.2 0.0 2.3 2 0 0 2 2 2 1 Predicted ATPase of the ABC class DUF258 PF03193.11 EIW84644.1 - 0.0022 17.1 0.0 0.005 16.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_15 PF13175.1 EIW84644.1 - 0.0025 16.9 0.0 0.0094 15.0 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EIW84644.1 - 0.0031 17.6 0.0 0.0098 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EIW84644.1 - 0.0054 16.6 0.0 0.026 14.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EIW84644.1 - 0.006 16.2 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_25 PF13481.1 EIW84644.1 - 0.0067 15.8 0.1 0.019 14.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain MobB PF03205.9 EIW84644.1 - 0.0067 16.1 0.0 0.021 14.5 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EIW84644.1 - 0.0077 16.1 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW84644.1 - 0.0082 15.8 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Miro PF08477.8 EIW84644.1 - 0.0083 16.6 0.0 0.025 15.0 0.0 1.9 2 0 0 2 2 1 1 Miro-like protein FtsK_SpoIIIE PF01580.13 EIW84644.1 - 0.0085 15.5 0.1 0.033 13.6 0.0 1.9 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_18 PF13238.1 EIW84644.1 - 0.015 15.6 0.0 0.046 14.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EIW84644.1 - 0.016 14.6 0.0 0.033 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_28 PF13521.1 EIW84644.1 - 0.02 14.8 0.0 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIW84644.1 - 0.037 13.1 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.18 EIW84644.1 - 0.039 13.9 0.0 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.1 EIW84644.1 - 0.041 13.4 0.0 0.081 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain MutS_V PF00488.16 EIW84644.1 - 0.053 12.9 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 MutS domain V T2SE PF00437.15 EIW84644.1 - 0.059 12.2 0.0 0.093 11.6 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_13 PF13166.1 EIW84644.1 - 0.068 11.6 0.0 0.29 9.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF3584 PF12128.3 EIW84644.1 - 0.08 10.2 0.1 0.12 9.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Arch_ATPase PF01637.13 EIW84644.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.6 2 0 0 2 2 1 0 Archaeal ATPase F-box-like PF12937.2 EIW84645.1 - 1.2e-08 34.5 1.2 3.7e-08 32.9 0.8 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW84645.1 - 0.01 15.4 0.4 0.028 14.0 0.3 1.9 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 EIW84646.1 - 7.3e-07 28.8 0.1 2.2e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 F-box-like MutS_III PF05192.13 EIW84646.1 - 0.013 15.2 0.0 0.4 10.4 0.0 2.3 2 1 0 2 2 2 0 MutS domain III SKG6 PF08693.5 EIW84647.1 - 1.8e-05 23.9 0.3 1.8e-05 23.9 0.2 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain EphA2_TM PF14575.1 EIW84647.1 - 0.0091 16.3 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.6 EIW84647.1 - 0.019 14.6 0.0 0.036 13.7 0.0 1.4 1 1 0 1 1 1 0 Protocadherin Syndecan PF01034.15 EIW84647.1 - 0.1 12.2 0.0 0.27 10.8 0.0 1.7 1 0 0 1 1 1 0 Syndecan domain SKG6 PF08693.5 EIW84648.1 - 3.3e-05 23.0 0.8 3.3e-05 23.0 0.6 2.3 2 0 0 2 2 2 1 Transmembrane alpha-helix domain EphA2_TM PF14575.1 EIW84648.1 - 0.014 15.8 0.0 0.028 14.8 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain F-box-like PF12937.2 EIW84649.1 - 5.8e-09 35.5 0.0 3.3e-08 33.1 0.0 2.4 2 0 0 2 2 2 1 F-box-like MitMem_reg PF13012.1 EIW84650.1 - 4.8e-37 126.5 0.5 8.4e-37 125.7 0.3 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EIW84650.1 - 7.8e-23 80.3 0.0 1.5e-22 79.4 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Trp_oprn_chp PF09534.5 EIW84650.1 - 0.076 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) COX4 PF02936.9 EIW84651.1 - 5.1e-38 130.0 0.0 5.8e-38 129.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Unstab_antitox PF09720.5 EIW84651.1 - 0.041 13.5 0.8 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 Putative addiction module component HMG_box_5 PF14887.1 EIW84651.1 - 0.089 12.5 0.6 0.52 10.1 0.2 2.1 2 0 0 2 2 2 0 HMG (high mobility group) box 5 F-box-like PF12937.2 EIW84652.1 - 8.4e-10 38.2 0.1 2.3e-09 36.8 0.1 1.8 1 0 0 1 1 1 1 F-box-like COG6 PF06419.6 EIW84653.1 - 3.2e-122 408.7 0.0 7.4e-122 407.5 0.0 1.4 1 1 0 1 1 1 1 Conserved oligomeric complex COG6 DUF869 PF05911.6 EIW84653.1 - 0.0062 14.8 0.7 0.011 14.0 0.5 1.3 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) ADIP PF11559.3 EIW84653.1 - 0.071 13.0 4.5 0.15 11.9 3.1 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF336 PF03928.9 EIW84654.1 - 1.3e-21 76.7 0.0 1.5e-21 76.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF336) PaRep2a PF07903.6 EIW84654.1 - 0.085 12.5 0.1 0.13 11.9 0.1 1.2 1 0 0 1 1 1 0 PaRep2a protein SKG6 PF08693.5 EIW84655.1 - 0.0006 19.0 0.2 0.0013 18.0 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Podoplanin PF05808.6 EIW84655.1 - 0.0023 17.4 0.2 0.0041 16.7 0.2 1.3 1 0 0 1 1 1 1 Podoplanin Beta-APP PF03494.8 EIW84655.1 - 0.54 9.7 7.2 2.8 7.4 5.0 2.2 1 1 0 1 1 1 0 Beta-amyloid peptide (beta-APP) DEAD PF00270.24 EIW84656.1 - 7.9e-42 142.6 2.1 2.8e-41 140.8 0.4 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW84656.1 - 7.5e-27 93.0 0.3 2.6e-26 91.2 0.1 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW84656.1 - 0.00086 19.1 0.0 0.0019 18.0 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EIW84656.1 - 0.0061 16.2 0.2 0.018 14.7 0.1 1.9 1 1 0 1 1 1 1 Part of AAA domain DUF1253 PF06862.7 EIW84656.1 - 0.0065 14.9 0.1 1.2 7.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1253) AAA_22 PF13401.1 EIW84656.1 - 0.027 14.6 0.2 0.15 12.2 0.2 2.2 1 1 0 1 1 1 0 AAA domain Flavi_DEAD PF07652.9 EIW84656.1 - 0.033 13.9 0.1 0.14 11.9 0.0 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain AAA_30 PF13604.1 EIW84656.1 - 0.065 12.8 0.4 0.17 11.4 0.2 1.8 2 1 0 2 2 2 0 AAA domain tRNA-synt_1b PF00579.20 EIW84656.1 - 0.079 12.0 0.0 0.26 10.3 0.0 1.8 2 0 0 2 2 2 0 tRNA synthetases class I (W and Y) DSPc PF00782.15 EIW84657.1 - 3.1e-22 78.5 0.0 5.7e-22 77.7 0.0 1.4 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIW84657.1 - 0.013 14.8 0.0 0.015 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 EIW84657.1 - 0.047 12.5 0.0 0.058 12.2 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase Ras PF00071.17 EIW84658.1 - 1.1e-49 167.9 0.0 1.3e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW84658.1 - 2.6e-14 53.7 0.0 3.5e-14 53.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW84658.1 - 1.9e-10 40.2 0.0 2.8e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIW84658.1 - 0.00041 19.8 0.0 0.01 15.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIW84658.1 - 0.0027 17.6 0.0 0.0047 16.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Toxin_53 PF15532.1 EIW84658.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative toxin 53 ATP-synt_Eps PF04627.8 EIW84659.1 - 1.1e-22 79.3 2.9 1.4e-22 78.9 2.0 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain HTH_19 PF12844.2 EIW84659.1 - 0.074 13.1 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain E1_dh PF00676.15 EIW84662.1 - 2.8e-115 384.1 0.0 3.3e-115 383.9 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EIW84662.1 - 0.00012 21.1 0.0 0.00019 20.4 0.0 1.4 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.16 EIW84662.1 - 0.0048 16.4 2.2 0.006 16.1 0.4 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Beta_elim_lyase PF01212.16 EIW84662.1 - 0.074 12.1 0.2 0.99 8.4 0.0 2.4 2 1 0 2 2 2 0 Beta-eliminating lyase Peptidase_S80 PF07230.6 EIW84662.1 - 0.1 10.9 0.0 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage T4-like capsid assembly protein (Gp20) HEAT_2 PF13646.1 EIW84663.1 - 3e-11 43.4 18.2 0.00097 19.3 0.2 7.0 3 2 3 6 6 6 3 HEAT repeats Arm PF00514.18 EIW84663.1 - 4.4e-09 35.8 19.8 0.047 13.5 0.1 9.1 11 0 0 11 11 11 3 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EIW84663.1 - 7.5e-07 28.7 22.4 0.014 15.4 0.0 9.5 9 0 0 9 9 9 1 HEAT repeat V-ATPase_H_N PF03224.9 EIW84663.1 - 3e-06 26.5 0.0 0.00065 18.9 0.0 2.8 2 1 1 3 3 3 1 V-ATPase subunit H HEAT_EZ PF13513.1 EIW84663.1 - 4.3e-05 23.8 19.5 0.12 12.9 0.1 6.9 7 1 1 8 8 7 2 HEAT-like repeat Proteasom_PSMB PF10508.4 EIW84663.1 - 0.0001 20.7 1.4 0.0046 15.2 0.5 2.5 1 1 2 3 3 3 2 Proteasome non-ATPase 26S subunit Cnd1 PF12717.2 EIW84663.1 - 0.00024 21.0 1.5 0.024 14.4 0.2 3.3 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.3 EIW84663.1 - 0.00044 20.1 1.1 1.6 8.6 0.0 4.3 4 1 1 5 5 5 1 V-ATPase subunit H Adaptin_N PF01602.15 EIW84663.1 - 0.002 16.5 6.1 0.0073 14.6 0.9 3.0 1 1 1 2 2 2 2 Adaptin N terminal region DUF3361 PF11841.3 EIW84663.1 - 0.007 16.0 2.5 0.033 13.8 0.1 2.9 3 1 1 4 4 4 1 Domain of unknown function (DUF3361) Ipi1_N PF12333.3 EIW84663.1 - 0.0074 16.2 3.1 0.61 10.0 0.0 4.1 4 1 1 5 5 5 1 Rix1 complex component involved in 60S ribosome maturation RICTOR_N PF14664.1 EIW84663.1 - 0.013 14.1 0.7 6.7 5.1 0.3 3.1 3 1 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, N-term Ric8 PF10165.4 EIW84663.1 - 0.025 13.4 0.6 0.36 9.5 0.4 2.6 2 1 1 3 3 3 0 Guanine nucleotide exchange factor synembryn MMS19_N PF14500.1 EIW84663.1 - 0.029 13.6 0.3 0.029 13.6 0.2 1.8 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II Orthopox_F14 PF06076.7 EIW84663.1 - 0.11 12.5 3.8 0.32 11.0 2.7 1.7 1 0 0 1 1 1 0 Orthopoxvirus F14 protein ABC_tran PF00005.22 EIW84664.1 - 7.3e-25 87.8 0.0 1.1e-24 87.3 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIW84664.1 - 2.4e-10 40.8 0.0 2e-08 34.5 0.0 2.4 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 EIW84664.1 - 2.1e-06 27.1 0.1 0.052 12.7 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EIW84664.1 - 4.6e-05 23.4 0.1 0.00015 21.7 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EIW84664.1 - 9.4e-05 23.2 0.1 0.00017 22.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.4 EIW84664.1 - 0.00019 20.1 0.0 0.033 12.7 0.0 2.3 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_23 PF13476.1 EIW84664.1 - 0.0002 21.7 0.0 0.00053 20.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.1 EIW84664.1 - 0.00028 20.3 0.0 0.00061 19.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EIW84664.1 - 0.00049 19.2 0.0 0.0072 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 EIW84664.1 - 0.0013 18.6 0.0 0.025 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EIW84664.1 - 0.0016 18.3 0.0 0.0042 16.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain DUF258 PF03193.11 EIW84664.1 - 0.0017 17.5 0.0 0.0035 16.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIW84664.1 - 0.0029 17.7 0.0 0.015 15.4 0.0 2.1 1 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EIW84664.1 - 0.0041 17.0 0.0 0.011 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EIW84664.1 - 0.0053 16.4 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain FtsK_SpoIIIE PF01580.13 EIW84664.1 - 0.0075 15.7 0.1 0.027 13.9 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.9 EIW84664.1 - 0.0077 15.9 0.0 0.021 14.5 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EIW84664.1 - 0.0078 15.6 0.4 0.027 13.8 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EIW84664.1 - 0.0078 15.6 0.1 0.032 13.6 0.0 1.9 2 0 0 2 2 2 1 AAA-like domain AAA_19 PF13245.1 EIW84664.1 - 0.0097 15.6 0.1 0.022 14.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_13 PF13166.1 EIW84664.1 - 0.017 13.6 0.0 0.28 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EIW84664.1 - 0.019 15.4 0.0 0.044 14.2 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein AAA_18 PF13238.1 EIW84664.1 - 0.029 14.6 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIW84664.1 - 0.029 13.4 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.18 EIW84664.1 - 0.031 14.2 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase T2SE PF00437.15 EIW84664.1 - 0.04 12.8 0.0 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_30 PF13604.1 EIW84664.1 - 0.055 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain MutS_V PF00488.16 EIW84664.1 - 0.062 12.6 0.1 0.14 11.5 0.0 1.6 2 0 0 2 2 1 0 MutS domain V Arch_ATPase PF01637.13 EIW84664.1 - 0.073 12.7 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase DUF3584 PF12128.3 EIW84664.1 - 0.078 10.3 0.1 0.12 9.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Dynamin_N PF00350.18 EIW84664.1 - 0.15 11.8 0.1 0.4 10.4 0.0 1.7 2 0 0 2 2 1 0 Dynamin family cobW PF02492.14 EIW84664.1 - 0.15 11.4 0.0 0.35 10.2 0.0 1.6 2 0 0 2 2 1 0 CobW/HypB/UreG, nucleotide-binding domain Dimer_Tnp_hAT PF05699.9 EIW84665.1 - 1.4e-06 27.8 0.0 1.4e-06 27.8 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SKG6 PF08693.5 EIW84666.1 - 0.00048 19.3 0.1 0.00083 18.6 0.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Syndecan PF01034.15 EIW84666.1 - 0.062 12.9 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain DUF3450 PF11932.3 EIW84667.1 - 0.0013 18.0 2.9 0.0013 18.0 2.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3450) IncA PF04156.9 EIW84667.1 - 0.1 12.1 22.6 0.031 13.8 0.7 4.5 5 0 0 5 5 5 0 IncA protein Pkinase PF00069.20 EIW84669.1 - 5.5e-34 117.4 0.0 6.3e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW84669.1 - 3.2e-23 82.1 0.0 3.6e-23 81.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW84669.1 - 0.00063 18.7 0.0 0.00072 18.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW84669.1 - 0.003 17.3 0.1 0.0049 16.6 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EIW84669.1 - 0.011 14.7 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EIW84669.1 - 0.072 11.9 0.1 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 UCH PF00443.24 EIW84670.1 - 3.6e-47 160.7 0.0 4.6e-47 160.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW84670.1 - 5.8e-09 35.8 0.0 2.6e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Nucleoplasmin PF03066.10 EIW84671.1 - 0.075 12.5 1.0 0.14 11.6 0.7 1.4 1 0 0 1 1 1 0 Nucleoplasmin Retrotrans_gag PF03732.12 EIW84672.1 - 3.7e-10 39.7 2.6 4.6e-10 39.4 1.3 1.5 1 1 0 1 1 1 1 Retrotransposon gag protein FAD_binding_3 PF01494.14 EIW84673.1 - 1.9e-72 244.2 0.0 2.6e-72 243.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIW84673.1 - 2.1e-06 27.7 0.0 6.4e-06 26.1 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW84673.1 - 2.4e-06 26.6 0.9 0.0001 21.3 0.1 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW84673.1 - 4.9e-06 26.4 0.0 1.5e-05 24.9 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EIW84673.1 - 1.1e-05 24.4 0.1 2e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EIW84673.1 - 2.7e-05 22.8 2.3 0.0001 20.9 0.0 2.3 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.22 EIW84673.1 - 3.4e-05 24.1 0.0 0.0011 19.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW84673.1 - 4.9e-05 22.5 0.0 9.9e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EIW84673.1 - 0.00024 20.3 0.1 0.0004 19.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EIW84673.1 - 0.00052 18.7 0.0 0.00074 18.2 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_3 PF13738.1 EIW84673.1 - 0.0026 17.8 0.0 0.0058 16.7 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIW84673.1 - 0.0069 15.2 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_7 PF13241.1 EIW84673.1 - 0.024 14.8 0.0 0.086 13.0 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EIW84673.1 - 0.025 14.3 0.0 0.052 13.3 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EIW84673.1 - 0.029 13.2 0.1 0.049 12.5 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Amino_oxidase PF01593.19 EIW84673.1 - 0.053 12.5 0.0 0.21 10.5 0.0 1.9 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase F-box-like PF12937.2 EIW84674.1 - 1e-10 41.1 1.0 4.2e-10 39.1 0.7 2.1 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EIW84674.1 - 0.00026 20.6 4.6 0.29 10.9 0.5 3.8 3 0 0 3 3 3 2 Leucine rich repeat LRR_7 PF13504.1 EIW84674.1 - 0.18 12.1 4.3 90 3.9 0.7 5.2 5 1 0 5 5 5 0 Leucine rich repeat F-box PF00646.28 EIW84674.1 - 0.21 11.2 3.2 0.45 10.2 0.6 2.5 1 1 1 2 2 2 0 F-box domain FAD_binding_3 PF01494.14 EIW84675.1 - 5.3e-47 160.5 0.1 3e-31 108.7 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EIW84675.1 - 0.00017 21.5 0.0 0.0006 19.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EIW84675.1 - 0.00053 18.7 0.0 0.0018 16.9 0.0 1.7 2 0 0 2 2 2 1 Tryptophan halogenase Thi4 PF01946.12 EIW84675.1 - 0.00059 18.9 0.2 0.0017 17.5 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EIW84675.1 - 0.00088 18.2 0.2 0.0019 17.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIW84675.1 - 0.002 17.0 3.7 0.0062 15.4 0.3 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EIW84675.1 - 0.0031 16.0 0.8 0.0053 15.2 0.2 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EIW84675.1 - 0.0032 16.6 0.7 0.0049 16.0 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW84675.1 - 0.0034 17.7 0.2 0.029 14.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW84675.1 - 0.0041 17.0 0.1 0.0081 16.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW84675.1 - 0.032 14.3 0.0 0.065 13.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EIW84675.1 - 0.096 11.7 0.0 0.13 11.2 0.0 1.2 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EIW84675.1 - 0.13 11.9 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EIW84676.1 - 3.2e-65 220.5 0.0 4.1e-65 220.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EIW84676.1 - 1.3e-05 24.0 0.7 0.00025 19.8 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase HI0933_like PF03486.9 EIW84676.1 - 1.7e-05 23.4 0.4 0.0035 15.8 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 EIW84676.1 - 2.6e-05 24.3 0.0 6e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW84676.1 - 3.2e-05 24.2 1.1 0.045 14.1 0.2 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW84676.1 - 3.3e-05 23.8 0.1 8.2e-05 22.5 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW84676.1 - 6.3e-05 22.0 0.6 0.0076 15.1 0.1 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW84676.1 - 0.00014 21.8 0.1 0.00045 20.1 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIW84676.1 - 0.00052 19.1 0.1 0.0012 18.0 0.1 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EIW84676.1 - 0.0033 16.3 1.4 0.005 15.7 0.4 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 EIW84676.1 - 0.044 14.0 0.0 0.14 12.4 0.0 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.16 EIW84676.1 - 0.068 12.9 0.2 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 ThiF family Lycopene_cycl PF05834.7 EIW84676.1 - 0.29 9.9 1.2 0.5 9.2 0.2 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.2 EIW84676.1 - 5.6 5.9 8.2 0.29 10.1 1.7 1.9 2 1 0 2 2 2 0 FAD dependent oxidoreductase RRP7 PF12923.2 EIW84677.1 - 6.4e-34 116.7 3.0 6.4e-34 116.7 2.1 1.6 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) RRM_1 PF00076.17 EIW84677.1 - 0.0018 17.8 2.6 0.0066 16.0 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW84677.1 - 0.0027 17.6 0.0 0.007 16.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PMT PF02366.13 EIW84678.1 - 3.2e-78 262.4 18.2 3.2e-78 262.4 12.6 2.4 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EIW84678.1 - 1.1e-30 106.6 0.4 1.7e-30 106.0 0.3 1.3 1 0 0 1 1 1 1 MIR domain Fibrillarin PF01269.12 EIW84679.1 - 3.2e-108 359.9 0.0 3.9e-108 359.6 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EIW84679.1 - 0.00069 19.1 0.1 0.0012 18.3 0.0 1.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EIW84679.1 - 0.0026 17.3 0.0 0.0039 16.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIW84679.1 - 0.0029 17.1 0.1 0.005 16.3 0.1 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EIW84679.1 - 0.0076 16.8 0.0 0.012 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EIW84679.1 - 0.19 10.8 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB PEMT PF04191.8 EIW84680.1 - 1.3e-07 31.6 0.2 2.1e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.9 EIW84680.1 - 5.7e-07 29.6 0.8 1.5e-06 28.2 0.4 1.7 1 1 1 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family ERG4_ERG24 PF01222.12 EIW84680.1 - 0.00019 20.1 0.6 0.00026 19.6 0.4 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1634 PF07843.6 EIW84680.1 - 0.02 14.5 0.6 0.034 13.7 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1634) Steroid_dh PF02544.11 EIW84680.1 - 0.05 13.3 0.1 0.089 12.5 0.0 1.4 1 0 0 1 1 1 0 3-oxo-5-alpha-steroid 4-dehydrogenase MFS_1 PF07690.11 EIW84681.1 - 5.9e-23 81.1 78.5 2.4e-17 62.6 28.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3270 PF11674.3 EIW84681.1 - 0.13 12.2 1.6 0.56 10.2 1.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) CBM_5_12 PF02839.9 EIW84682.1 - 1.9e-13 49.7 25.3 2e-08 33.6 6.3 4.5 5 1 0 5 5 5 2 Carbohydrate binding domain Tmp39 PF10271.4 EIW84682.1 - 0.11 11.1 1.1 0.16 10.6 0.8 1.1 1 0 0 1 1 1 0 Putative transmembrane protein Amnionless PF14828.1 EIW84683.1 - 0.0013 17.3 0.0 0.0014 17.2 0.0 1.0 1 0 0 1 1 1 1 Amnionless SKG6 PF08693.5 EIW84683.1 - 0.0019 17.4 1.5 0.0028 16.9 1.0 1.3 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4083 PF13314.1 EIW84683.1 - 0.0073 16.1 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4083) Colicin_V PF02674.11 EIW84683.1 - 0.013 15.3 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 Colicin V production protein Podoplanin PF05808.6 EIW84683.1 - 0.014 14.9 1.7 0.018 14.6 1.1 1.1 1 0 0 1 1 1 0 Podoplanin EphA2_TM PF14575.1 EIW84683.1 - 0.015 15.7 0.0 0.021 15.2 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF2613 PF11021.3 EIW84683.1 - 0.016 14.8 1.8 0.017 14.7 0.4 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2613) Yip1 PF04893.12 EIW84683.1 - 0.043 13.3 1.0 0.051 13.0 0.7 1.1 1 0 0 1 1 1 0 Yip1 domain Syndecan PF01034.15 EIW84683.1 - 0.086 12.4 0.2 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain Protocadherin PF08374.6 EIW84683.1 - 0.17 11.5 1.4 0.22 11.1 1.0 1.3 1 1 0 1 1 1 0 Protocadherin Beta-APP PF03494.8 EIW84683.1 - 0.65 9.5 6.3 1.3 8.5 4.3 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Rick_17kDa_Anti PF05433.10 EIW84683.1 - 2.1 8.0 15.5 0.2 11.3 6.5 2.0 2 0 0 2 2 2 0 Glycine zipper 2TM domain Bacteriocin_IIc PF10439.4 EIW84683.1 - 2.2 8.4 7.8 1.1 9.3 3.0 1.9 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.1 EIW84683.1 - 4.9 6.8 15.7 0.41 10.3 6.6 2.0 2 0 0 2 2 2 0 Glycine zipper zf-C3HC4_3 PF13920.1 EIW84684.1 - 6e-05 22.6 6.3 6e-05 22.6 4.3 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.21 EIW84684.1 - 7.6 7.1 21.9 1.4 9.4 2.8 4.8 5 0 0 5 5 5 0 Zinc finger, C2H2 type F-box-like PF12937.2 EIW84685.1 - 1.6e-07 30.8 1.9 4.4e-07 29.5 0.1 2.6 1 1 1 2 2 2 1 F-box-like F-box PF00646.28 EIW84685.1 - 0.1 12.3 1.0 1.2 8.9 0.1 2.7 3 0 0 3 3 3 0 F-box domain Choline_transpo PF04515.7 EIW84686.1 - 1.5e-22 79.8 12.9 1.2e-21 76.8 8.9 2.4 1 1 0 1 1 1 1 Plasma-membrane choline transporter BAF1_ABF1 PF04684.8 EIW84686.1 - 0.12 11.1 7.3 0.22 10.3 5.0 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Podoplanin PF05808.6 EIW84687.1 - 0.0012 18.4 0.2 0.002 17.7 0.1 1.3 1 0 0 1 1 1 1 Podoplanin Herpes_gE PF02480.11 EIW84687.1 - 0.0093 14.2 0.0 0.014 13.7 0.0 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Rick_17kDa_Anti PF05433.10 EIW84687.1 - 0.027 14.1 8.2 0.063 12.9 5.7 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 EIW84687.1 - 0.047 13.3 1.9 0.098 12.3 1.3 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Asp_protease_2 PF13650.1 EIW84689.1 - 4.2e-09 36.7 0.0 5.1e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.1 EIW84689.1 - 4.5e-06 26.3 0.0 6e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EIW84689.1 - 1.3e-05 24.9 0.0 1.9e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Peptidase_A2B PF12384.3 EIW84689.1 - 0.00055 19.3 0.0 0.00067 19.0 0.0 1.0 1 0 0 1 1 1 1 Ty3 transposon peptidase Sod_Fe_C PF02777.13 EIW84689.1 - 0.04 13.7 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, C-terminal domain zf-RVT PF13966.1 EIW84694.1 - 0.0035 17.6 0.1 0.0052 17.0 0.1 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase DUF1569 PF07606.6 EIW84694.1 - 0.055 13.3 0.0 0.072 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1569) TatD_DNase PF01026.16 EIW84694.1 - 0.074 12.2 0.0 0.08 12.1 0.0 1.0 1 0 0 1 1 1 0 TatD related DNase WD40 PF00400.27 EIW84695.1 - 2.5e-09 36.6 14.3 0.018 14.9 0.0 6.7 6 1 0 6 6 6 4 WD domain, G-beta repeat ADH_zinc_N PF00107.21 EIW84696.1 - 6.2e-25 87.2 0.3 6.2e-25 87.2 0.2 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW84696.1 - 1.6e-12 48.4 0.4 2.9e-12 47.5 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW84696.1 - 0.005 16.5 0.2 0.061 13.0 0.2 2.5 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.5 EIW84696.1 - 0.027 14.4 0.1 0.22 11.5 0.0 2.3 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal DUF1191 PF06697.7 EIW84698.1 - 0.011 14.5 0.1 0.021 13.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) SKG6 PF08693.5 EIW84698.1 - 0.026 13.8 0.0 0.054 12.8 0.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain BCMA-Tall_bind PF09257.5 EIW84699.1 - 1.1 9.2 14.6 1.3 8.9 4.8 2.6 2 0 0 2 2 2 0 BCMA, TALL-1 binding DUF1191 PF06697.7 EIW84701.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) NCU-G1 PF15065.1 EIW84701.1 - 0.11 11.1 0.2 0.63 8.6 0.0 2.0 2 0 0 2 2 2 0 Lysosomal transcription factor, NCU-G1 PepSY_TM_2 PF13703.1 EIW84701.1 - 0.18 11.9 0.3 0.36 11.0 0.0 1.6 2 0 0 2 2 2 0 PepSY-associated TM helix F-box-like PF12937.2 EIW84702.1 - 2.4e-07 30.3 0.7 7.8e-07 28.7 0.5 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW84702.1 - 0.00036 20.0 0.3 0.0017 17.9 0.2 2.2 1 0 0 1 1 1 1 F-box domain DSPc PF00782.15 EIW84705.1 - 1.3e-27 95.9 0.0 1.8e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIW84705.1 - 2.1e-05 23.9 0.0 3.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase FMO-like PF00743.14 EIW84706.1 - 1.6e-21 76.1 0.0 3.4e-11 42.0 0.0 3.3 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EIW84706.1 - 4e-12 46.6 0.0 6.3e-07 29.6 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW84706.1 - 1.7e-10 41.1 0.0 0.00053 19.9 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW84706.1 - 1.8e-09 37.4 0.2 9.9e-09 35.1 0.0 2.4 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EIW84706.1 - 2.6e-06 26.5 0.0 0.00043 19.3 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EIW84706.1 - 1.3e-05 24.3 0.0 2.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EIW84706.1 - 2.3e-05 23.5 0.0 9.3e-05 21.6 0.0 1.8 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 EIW84706.1 - 0.00015 21.6 0.0 0.00059 19.6 0.0 2.1 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EIW84706.1 - 0.00022 20.3 0.0 0.00038 19.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EIW84706.1 - 0.00041 19.5 0.0 0.00075 18.6 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EIW84706.1 - 0.0023 16.4 0.0 0.0035 15.8 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EIW84706.1 - 0.058 12.2 0.0 0.078 11.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EIW84706.1 - 0.11 12.8 0.1 1 9.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.2 EIW84707.1 - 2.7e-11 42.9 1.7 7.1e-11 41.6 1.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW84707.1 - 0.00071 19.1 0.3 0.002 17.7 0.2 1.8 1 0 0 1 1 1 1 F-box domain p450 PF00067.17 EIW84708.1 - 7.4e-65 219.2 0.0 2.5e-50 171.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF605 PF04652.11 EIW84709.1 - 2.2 7.6 6.3 2.2 7.5 4.4 1.1 1 0 0 1 1 1 0 Vta1 like RNA_pol_L_2 PF13656.1 EIW84710.1 - 2.8e-27 93.9 0.0 4.4e-27 93.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EIW84710.1 - 1e-09 37.3 0.0 1.5e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Yqai PF09466.5 EIW84710.1 - 0.053 13.5 0.0 0.088 12.8 0.0 1.3 1 0 0 1 1 1 0 Hypothetical protein Yqai Glyco_hydro_10 PF00331.15 EIW84711.1 - 8.6e-89 297.7 0.0 9.7e-89 297.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 MFS_1 PF07690.11 EIW84712.1 - 3.8e-51 173.8 45.9 3.8e-51 173.8 31.8 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIW84712.1 - 9e-18 63.7 16.4 1.1e-17 63.4 11.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIW84712.1 - 2.8e-12 45.9 14.2 2.8e-12 45.9 9.8 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter IncA PF04156.9 EIW84712.1 - 0.009 15.6 1.7 0.032 13.8 1.2 1.9 1 0 0 1 1 1 1 IncA protein DUF872 PF05915.7 EIW84712.1 - 0.022 14.6 0.8 0.022 14.6 0.6 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) B12D PF06522.6 EIW84712.1 - 0.057 13.1 0.1 0.32 10.7 0.1 2.4 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit HlyIII PF03006.15 EIW84712.1 - 0.08 12.3 21.9 40 3.5 14.2 3.7 1 1 1 2 2 2 0 Haemolysin-III related DUF3185 PF11381.3 EIW84712.1 - 0.24 11.1 10.3 11 5.8 7.2 3.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3185) DUF3040 PF11239.3 EIW84712.1 - 1.7 8.7 11.6 0.089 12.8 2.7 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3040) Neurensin PF14927.1 EIW84712.1 - 4.1 6.7 7.9 3.5 6.9 2.4 2.8 2 1 1 3 3 3 0 Neurensin WD40 PF00400.27 EIW84713.1 - 6.5e-18 63.8 6.3 2.4e-06 27.2 0.2 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat PD40 PF07676.7 EIW84713.1 - 0.0023 17.5 8.7 7.7 6.2 0.0 5.7 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat SGL PF08450.7 EIW84713.1 - 0.012 15.0 0.0 2.4 7.4 0.0 2.5 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Reg_prop PF07494.6 EIW84713.1 - 0.1 12.6 0.0 82 3.7 0.0 3.8 3 0 0 3 3 3 0 Two component regulator propeller PQQ_2 PF13360.1 EIW84713.1 - 0.12 11.7 0.0 0.3 10.4 0.0 1.6 2 0 0 2 2 2 0 PQQ-like domain GMC_oxred_N PF00732.14 EIW84714.1 - 8.6e-58 195.8 0.0 1.2e-57 195.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIW84714.1 - 2.2e-33 115.5 0.5 3.4e-33 114.9 0.3 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIW84714.1 - 8.3e-10 38.0 0.0 2.2e-05 23.5 0.0 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW84714.1 - 6.9e-06 25.1 0.7 0.00031 19.7 0.1 2.7 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.1 EIW84714.1 - 1.8e-05 24.6 0.5 6.1e-05 22.9 0.3 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIW84714.1 - 0.0024 16.8 0.2 0.0038 16.2 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EIW84714.1 - 0.0024 16.9 0.5 0.0039 16.2 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIW84714.1 - 0.0036 17.1 0.0 0.0073 16.1 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW84714.1 - 0.011 14.2 0.4 0.024 13.1 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein GIDA PF01134.17 EIW84714.1 - 0.014 14.3 0.3 0.23 10.2 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EIW84714.1 - 0.018 15.1 0.0 0.68 9.9 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW84714.1 - 0.024 13.7 0.1 0.052 12.6 0.1 1.5 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 EIW84714.1 - 0.044 13.7 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Trp_halogenase PF04820.9 EIW84714.1 - 0.1 11.2 0.4 0.14 10.7 0.2 1.1 1 0 0 1 1 1 0 Tryptophan halogenase FAA_hydrolase PF01557.13 EIW84715.1 - 1e-55 188.5 0.0 1.2e-55 188.3 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family KH_2 PF07650.12 EIW84715.1 - 0.028 13.9 0.0 0.47 10.0 0.0 2.2 2 0 0 2 2 2 0 KH domain p450 PF00067.17 EIW84716.1 - 6.1e-60 203.0 0.0 2.5e-50 171.3 0.0 3.0 2 1 1 3 3 3 3 Cytochrome P450 Terpene_synth_C PF03936.11 EIW84717.1 - 3.7e-10 39.4 0.0 5.1e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain 4HBT PF03061.17 EIW84718.1 - 1.8e-14 53.6 0.5 3.9e-14 52.5 0.3 1.6 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EIW84718.1 - 0.00013 21.9 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) TPP_enzyme_N PF02776.13 EIW84719.1 - 1.4e-57 193.8 0.1 1.5e-56 190.5 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EIW84719.1 - 5.7e-46 155.8 0.6 1.3e-44 151.4 0.2 2.6 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EIW84719.1 - 1.3e-38 131.8 0.8 4e-38 130.2 0.3 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain SAPS PF04499.10 EIW84723.1 - 2.5e-119 399.0 0.0 3.3e-119 398.6 0.0 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Adap_comp_sub PF00928.16 EIW84724.1 - 5.1e-82 274.9 0.0 6.5e-82 274.5 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EIW84724.1 - 1.5e-05 24.7 0.3 2.5e-05 24.0 0.2 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pro_isomerase PF00160.16 EIW84728.1 - 7.9e-50 169.0 0.0 8.7e-50 168.9 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PSI_PsaJ PF01701.13 EIW84729.1 - 1.6 8.5 5.5 0.65 9.7 0.2 3.0 3 0 0 3 3 3 0 Photosystem I reaction centre subunit IX / PsaJ CENP-T PF15511.1 EIW84733.1 - 0.68 9.1 5.8 0.69 9.0 4.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Sporozoite_P67 PF05642.6 EIW84733.1 - 5.1 4.8 9.7 6.2 4.5 6.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PAP_assoc PF03828.14 EIW84734.1 - 4.3e-17 61.8 0.1 9.5e-17 60.7 0.1 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EIW84734.1 - 2.4e-08 34.1 0.0 6.1e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.1 EIW84734.1 - 0.03 14.3 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase beta palm PI3K_1B_p101 PF10486.4 EIW84734.1 - 0.41 8.1 5.0 0.58 7.6 3.5 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Kelch_5 PF13854.1 EIW84735.1 - 0.077 12.9 0.0 15 5.6 0.0 2.4 2 0 0 2 2 2 0 Kelch motif Sulfate_tra_GLY PF13792.1 EIW84736.1 - 1.6 8.4 7.6 2.2 8.0 0.3 2.5 2 0 0 2 2 2 0 Sulfate transporter N-terminal domain with GLY motif DUF2085 PF09858.4 EIW84736.1 - 2.5 8.2 7.7 3.5 7.7 1.2 3.3 1 1 3 4 4 4 0 Predicted membrane protein (DUF2085) Dioxygenase_C PF00775.16 EIW84737.1 - 7.2e-51 172.0 0.0 9.4e-51 171.6 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EIW84737.1 - 1.8e-10 40.6 0.0 6.4e-10 38.8 0.0 2.0 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EIW84737.1 - 1.7e-05 24.7 0.0 5.8e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.4 EIW84737.1 - 0.0076 16.2 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4198) WD40 PF00400.27 EIW84738.1 - 3.6e-16 58.3 32.9 2.2e-10 39.9 0.1 10.5 13 0 0 13 13 13 4 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW84738.1 - 2.5e-09 36.9 0.3 0.0038 16.7 0.1 4.2 3 1 1 4 4 4 3 PQQ-like domain eIF2A PF08662.6 EIW84738.1 - 1.4e-06 28.1 0.0 1.5 8.5 0.0 4.5 5 0 0 5 5 5 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EIW84738.1 - 0.00053 18.8 0.0 0.14 10.8 0.0 3.9 3 2 1 4 4 4 1 Nup133 N terminal like PQQ PF01011.16 EIW84738.1 - 0.0016 17.8 0.4 13 5.5 0.0 4.8 4 1 0 5 5 5 1 PQQ enzyme repeat SGL PF08450.7 EIW84738.1 - 0.03 13.7 0.0 0.24 10.7 0.0 2.5 2 1 1 3 3 3 0 SMP-30/Gluconolaconase/LRE-like region PD40 PF07676.7 EIW84738.1 - 0.35 10.5 4.1 44 3.8 0.0 4.8 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat MFS_1 PF07690.11 EIW84739.1 - 1.4e-50 171.9 44.0 2.4e-50 171.2 30.5 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EIW84739.1 - 1.7e-17 62.8 15.7 2.2e-17 62.5 10.9 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIW84739.1 - 1.7e-13 49.9 14.8 1.7e-13 49.9 10.3 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter IncA PF04156.9 EIW84739.1 - 0.009 15.6 1.1 0.009 15.6 0.8 2.2 2 0 0 2 2 2 1 IncA protein B12D PF06522.6 EIW84739.1 - 0.16 11.6 0.1 0.67 9.6 0.1 2.1 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF872 PF05915.7 EIW84739.1 - 1.1 9.1 6.0 0.14 12.0 0.5 2.4 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) TauE PF01925.14 EIW84739.1 - 3.1 7.1 54.7 0.42 10.0 3.0 4.2 2 1 1 3 3 3 0 Sulfite exporter TauE/SafE F-box-like PF12937.2 EIW84741.1 - 8.1e-10 38.2 1.7 2.4e-09 36.7 0.7 2.2 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.1 EIW84741.1 - 0.55 10.0 9.0 0.89 9.3 0.6 4.3 3 1 1 4 4 4 0 Leucine rich repeat DUF3947 PF13135.1 EIW84742.1 - 0.6 10.3 4.8 11 6.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3947) Fungal_trans PF04082.13 EIW84743.1 - 5.2e-18 64.8 0.1 9.8e-18 63.9 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW84743.1 - 1e-05 25.3 7.5 2e-05 24.3 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain WD40 PF00400.27 EIW84744.1 - 3.2e-57 188.4 23.7 2.4e-10 39.8 0.3 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EIW84744.1 - 2.2e-11 43.2 0.7 4.8e-11 42.2 0.5 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW84744.1 - 1.3e-09 37.4 0.3 3.1e-09 36.2 0.1 1.8 1 1 0 1 1 1 1 F-box domain Nup160 PF11715.3 EIW84744.1 - 4.7e-07 28.3 14.0 0.031 12.4 0.1 6.0 3 3 1 6 6 6 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIW84744.1 - 0.0045 15.7 1.5 5 5.7 0.0 4.0 2 2 1 4 4 4 2 Nup133 N terminal like Daxx PF03344.10 EIW84744.1 - 0.33 9.3 22.8 0.48 8.8 15.8 1.1 1 0 0 1 1 1 0 Daxx Family DUF572 PF04502.8 EIW84744.1 - 9.5 5.3 16.7 14 4.7 11.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4537 PF15057.1 EIW84745.1 - 0.0029 17.3 0.0 0.013 15.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4537) PWWP PF00855.12 EIW84745.1 - 0.0053 16.9 0.1 4.7 7.4 0.0 2.8 2 0 0 2 2 2 2 PWWP domain ELL PF10390.4 EIW84745.1 - 0.94 8.6 5.2 1.9 7.6 3.6 1.5 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL DUF1751 PF08551.5 EIW84746.1 - 0.4 11.0 5.3 0.35 11.2 0.7 2.5 1 1 0 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) PSI_PsaJ PF01701.13 EIW84746.1 - 6.8 6.5 8.6 0.35 10.6 0.1 3.3 4 0 0 4 4 4 0 Photosystem I reaction centre subunit IX / PsaJ GDA1_CD39 PF01150.12 EIW84748.1 - 1.4e-99 333.5 0.0 1.1e-91 307.5 0.0 2.0 2 0 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 EIW84748.1 - 0.067 12.3 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Ppx/GppA phosphatase family NAD_binding_10 PF13460.1 EIW84749.1 - 5e-07 29.9 0.0 0.011 15.7 0.0 3.2 1 1 0 2 2 2 2 NADH(P)-binding adh_short PF00106.20 EIW84749.1 - 0.00075 19.4 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW84749.1 - 0.0019 18.0 0.0 0.0075 16.0 0.0 1.8 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.8 EIW84749.1 - 0.011 14.9 0.0 0.21 10.7 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family Epimerase PF01370.16 EIW84749.1 - 0.018 14.5 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family F-box-like PF12937.2 EIW84750.1 - 7.1e-12 44.8 0.1 1.7e-11 43.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIW84750.1 - 0.0037 16.8 5.0 0.006 16.1 0.6 3.2 3 1 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW84750.1 - 0.27 11.0 7.0 0.49 10.1 1.0 3.3 3 1 1 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 EIW84750.1 - 8.5 6.8 7.3 1.8 8.9 1.0 3.2 3 1 0 3 3 3 0 Leucine Rich Repeat NADH5_C PF06455.6 EIW84751.1 - 0.019 14.3 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus PAD_M PF08527.5 EIW84753.1 - 0.16 11.3 0.0 0.32 10.3 0.0 1.5 1 0 0 1 1 1 0 Protein-arginine deiminase (PAD) middle domain Radical_SAM PF04055.16 EIW84754.1 - 3.9e-15 56.4 0.1 1.7e-14 54.3 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EIW84754.1 - 1.1e-11 44.5 0.1 3e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EIW84754.1 - 0.028 14.1 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.1 EIW84754.1 - 0.033 14.3 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Mit_ribos_Mrp51 PF11709.3 EIW84755.1 - 2.2e-07 30.4 0.0 7e-07 28.7 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit Nuc_sug_transp PF04142.10 EIW84756.1 - 4.9e-72 241.9 16.8 8.4e-72 241.1 11.7 1.3 1 1 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 EIW84756.1 - 1.1e-07 32.0 3.2 1.1e-07 32.0 2.2 2.9 2 1 0 2 2 2 1 Multidrug resistance efflux transporter TPT PF03151.11 EIW84756.1 - 4.3e-06 26.4 4.1 4.3e-06 26.4 2.8 3.3 2 2 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EIW84756.1 - 4.5e-06 25.7 7.6 6.4e-06 25.2 5.3 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EIW84756.1 - 0.00066 19.7 2.5 0.00066 19.7 1.7 2.8 3 0 0 3 3 3 2 EamA-like transporter family F-box-like PF12937.2 EIW84758.1 - 5.6e-09 35.5 0.5 2.1e-08 33.7 0.1 2.2 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 EIW84758.1 - 0.21 11.3 0.0 0.21 11.3 0.0 2.3 3 0 0 3 3 3 0 F-box domain Tyr_Deacylase PF02580.11 EIW84761.1 - 1.5e-49 167.6 0.0 1.9e-49 167.3 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Toprim_C_rpt PF13368.1 EIW84761.1 - 0.054 13.9 0.4 5.5 7.5 0.6 2.4 2 0 0 2 2 2 0 Topoisomerase C-terminal repeat PLDc_2 PF13091.1 EIW84762.1 - 4.8e-09 36.0 0.0 0.00012 21.8 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EIW84762.1 - 0.00027 20.6 0.0 0.25 11.2 0.0 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif zf-C3HC4_3 PF13920.1 EIW84763.1 - 3.9e-08 32.8 16.5 3.9e-08 32.8 11.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Cyclin PF08613.6 EIW84764.1 - 7.7e-11 42.6 0.2 1.5e-10 41.6 0.0 1.6 2 0 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EIW84764.1 - 2e-10 40.3 0.0 2.9e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Cyclin, N-terminal domain zf-C4H2 PF10146.4 EIW84765.1 - 1.1e-08 35.3 0.9 1.3e-08 35.1 0.6 1.1 1 0 0 1 1 1 1 Zinc finger-containing protein Lge1 PF11488.3 EIW84765.1 - 0.11 12.6 7.7 0.37 11.0 1.1 3.1 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 IncA PF04156.9 EIW84765.1 - 0.21 11.1 9.9 0.34 10.4 6.9 1.4 1 0 0 1 1 1 0 IncA protein DUF4047 PF13256.1 EIW84765.1 - 0.3 11.0 2.8 0.63 10.0 1.8 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) TBPIP PF07106.8 EIW84765.1 - 0.64 9.5 8.1 0.85 9.1 5.3 1.4 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) APG6 PF04111.7 EIW84765.1 - 1.5 7.8 7.9 2 7.3 5.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 UPF0242 PF06785.6 EIW84765.1 - 5.4 5.5 6.5 6.4 5.3 4.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DivIC PF04977.10 EIW84765.1 - 6.5 6.3 6.9 3.5 7.1 1.3 2.3 1 1 1 2 2 2 0 Septum formation initiator Acetyltransf_1 PF00583.19 EIW84766.1 - 1e-11 44.7 0.0 1.9e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EIW84766.1 - 7.2e-07 28.8 0.0 1.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EIW84766.1 - 7.4e-06 26.0 0.0 1e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIW84766.1 - 6.7e-05 22.9 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EIW84766.1 - 0.00043 20.1 0.3 0.0012 18.6 0.2 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EIW84766.1 - 0.015 15.2 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3608 PF12257.3 EIW84767.1 - 9.5e-60 201.8 0.0 1.6e-44 151.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3608) DEP PF00610.16 EIW84767.1 - 5.7e-20 70.8 0.2 1.5e-19 69.4 0.0 1.8 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Na_trans_assoc PF06512.8 EIW84768.1 - 0.024 14.6 0.6 0.024 14.6 0.4 2.2 1 1 0 2 2 2 0 Sodium ion transport-associated DHQS PF01959.11 EIW84768.1 - 0.076 11.7 0.1 0.1 11.2 0.1 1.1 1 0 0 1 1 1 0 3-dehydroquinate synthase (EC 4.6.1.3) Yip1 PF04893.12 EIW84769.1 - 0.015 14.8 0.3 0.015 14.8 0.2 1.8 2 0 0 2 2 2 0 Yip1 domain ADP_ribosyl_GH PF03747.9 EIW84769.1 - 0.087 12.5 1.2 0.12 12.0 0.8 1.2 1 0 0 1 1 1 0 ADP-ribosylglycohydrolase Phage_HK97_TLTM PF06120.6 EIW84769.1 - 0.27 10.5 1.1 0.36 10.1 0.7 1.1 1 0 0 1 1 1 0 Tail length tape measure protein DUF1183 PF06682.7 EIW84769.1 - 0.43 10.1 3.1 0.3 10.6 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) SKG6 PF08693.5 EIW84769.1 - 7.8 5.9 8.8 0.32 10.3 1.0 2.2 2 0 0 2 2 2 0 Transmembrane alpha-helix domain GST_N_3 PF13417.1 EIW84770.1 - 1e-09 38.4 0.4 3.8e-09 36.6 0.3 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW84770.1 - 2.3e-06 27.5 0.0 5.9e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW84770.1 - 5.3e-06 26.3 0.0 1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW84770.1 - 1.3e-05 25.0 0.1 3.3e-05 23.6 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW84770.1 - 0.055 13.9 0.3 0.092 13.2 0.2 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW84770.1 - 0.079 13.1 0.0 0.15 12.2 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain COX15-CtaA PF02628.10 EIW84771.1 - 0.043 12.6 0.9 0.072 11.9 0.6 1.3 1 0 0 1 1 1 0 Cytochrome oxidase assembly protein COPI_assoc PF08507.5 EIW84771.1 - 4 7.1 10.2 20 4.8 6.8 2.0 1 1 0 1 1 1 0 COPI associated protein Tyr_Deacylase PF02580.11 EIW84772.1 - 1e-06 28.7 0.0 4.6e-06 26.6 0.0 1.9 2 0 0 2 2 2 1 D-Tyr-tRNA(Tyr) deacylase ACP_syn_III PF08545.5 EIW84772.1 - 0.076 12.6 3.0 0.17 11.5 0.2 2.4 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III eIF2_C PF09173.6 EIW84772.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.6 1 0 0 1 1 1 0 Initiation factor eIF2 gamma, C terminal WD40 PF00400.27 EIW84773.1 - 0.013 15.3 0.0 5.3 7.0 0.0 2.3 2 0 0 2 2 2 0 WD domain, G-beta repeat WD40 PF00400.27 EIW84774.1 - 4.6e-49 162.6 29.1 1.3e-09 37.5 0.7 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW84774.1 - 1.1e-08 34.8 2.6 0.031 13.7 0.1 3.4 2 1 1 3 3 3 3 PQQ-like domain Nup160 PF11715.3 EIW84774.1 - 2.8e-06 25.7 13.0 0.037 12.1 0.1 4.7 2 2 1 4 4 4 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIW84774.1 - 4.1e-05 22.5 2.4 0.1 11.3 0.1 4.2 2 2 1 3 3 3 2 Nup133 N terminal like PQQ_3 PF13570.1 EIW84774.1 - 0.00021 21.4 3.1 6.5 7.1 0.1 5.2 5 0 0 5 5 5 2 PQQ-like domain DUF91 PF01939.11 EIW84774.1 - 0.11 11.6 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF91 Tet_JBP PF12851.2 EIW84777.1 - 9.8e-17 60.7 0.0 1.1e-16 60.5 0.0 1.0 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily TFIIF_alpha PF05793.7 EIW84779.1 - 0.19 10.0 58.1 0.42 8.9 40.3 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) KIAA1430 PF13879.1 EIW84781.1 - 1 9.8 3.9 0.3 11.5 0.1 2.0 2 0 0 2 2 2 0 KIAA1430 homologue Spore_coat_CotO PF14153.1 EIW84781.1 - 1.7 8.0 11.9 3.9 6.8 8.2 1.7 1 0 0 1 1 1 0 Spore coat protein CotO ODV-E18 PF10717.4 EIW84782.1 - 0.042 13.3 0.2 0.09 12.2 0.1 1.5 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF1352 PF07086.7 EIW84782.1 - 0.13 11.8 1.9 0.25 10.9 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1352) DUF1514 PF07438.6 EIW84782.1 - 7.5 6.5 8.0 0.36 10.7 1.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF1514) ETRAMP PF09716.5 EIW84782.1 - 8.5 6.4 6.4 1.5 8.8 0.4 2.6 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) tRNA_Me_trans PF03054.11 EIW84783.1 - 1.2e-110 369.4 0.0 1.3e-110 369.3 0.0 1.0 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.9 EIW84783.1 - 0.05 13.0 0.0 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) NAD_synthase PF02540.12 EIW84783.1 - 0.17 10.7 0.0 2.4 7.0 0.0 2.2 2 0 0 2 2 2 0 NAD synthase CENP-C_C PF11699.3 EIW84784.1 - 6.3e-27 93.3 0.0 1.8e-26 91.9 0.0 1.8 2 0 0 2 2 2 1 Mif2/CENP-C like Cupin_2 PF07883.6 EIW84784.1 - 0.00016 21.0 0.0 0.00032 20.1 0.0 1.5 1 0 0 1 1 1 1 Cupin domain F-box-like PF12937.2 EIW84785.1 - 4.1e-08 32.8 0.4 1.6e-07 30.9 0.0 2.2 2 1 0 2 2 2 1 F-box-like Methyltransf_3 PF01596.12 EIW84786.1 - 2.6e-46 157.2 0.0 3e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EIW84786.1 - 4.1e-15 56.5 0.0 1.3e-14 54.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW84786.1 - 3.6e-12 46.8 0.0 8e-12 45.7 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW84786.1 - 8.7e-11 41.6 0.0 2.3e-10 40.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW84786.1 - 6.8e-07 29.3 0.0 2.4e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIW84786.1 - 6.8e-06 25.7 0.0 8.2e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 EIW84786.1 - 7.2e-06 26.4 0.0 3.9e-05 24.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain GCD14 PF08704.5 EIW84786.1 - 1.1e-05 25.1 0.0 1.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit CMAS PF02353.15 EIW84786.1 - 0.0021 17.1 0.0 0.0057 15.7 0.0 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EIW84786.1 - 0.013 14.9 0.0 0.048 13.0 0.0 2.0 1 1 1 2 2 2 0 Methyltransferase small domain Methyltransf_15 PF09445.5 EIW84786.1 - 0.023 14.2 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.10 EIW84786.1 - 0.059 12.7 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 AAA_5 PF07728.9 EIW84788.1 - 1.4e-12 47.5 0.0 2.5e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EIW84788.1 - 1.4e-09 38.0 0.0 3.5e-09 36.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EIW84788.1 - 6e-06 26.4 0.0 1.6e-05 25.1 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIW84788.1 - 3.6e-05 23.9 0.0 0.00012 22.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW84788.1 - 0.00015 21.8 0.2 0.044 13.7 0.1 3.0 2 1 1 3 3 3 1 AAA ATPase domain Ank_2 PF12796.2 EIW84788.1 - 0.00022 21.5 0.0 0.00044 20.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) AAA_14 PF13173.1 EIW84788.1 - 0.0023 17.8 0.0 0.0044 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EIW84788.1 - 0.0027 17.8 0.0 0.0057 16.8 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.16 EIW84788.1 - 0.0028 16.8 0.0 0.012 14.7 0.0 2.0 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_PrkA PF08298.6 EIW84788.1 - 0.0061 15.2 0.0 0.012 14.3 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain AAA_33 PF13671.1 EIW84788.1 - 0.014 15.2 0.1 0.041 13.7 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EIW84788.1 - 0.058 14.2 0.0 0.16 12.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EIW84788.1 - 0.073 12.5 0.0 0.19 11.2 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EIW84788.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF258 PF03193.11 EIW84788.1 - 0.12 11.5 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Herpes_gE PF02480.11 EIW84789.1 - 0.016 13.5 0.0 0.028 12.6 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PgaD PF13994.1 EIW84789.1 - 0.072 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 PgaD-like protein P12 PF12669.2 EIW84789.1 - 0.19 11.9 0.3 0.27 11.4 0.2 1.2 1 0 0 1 1 1 0 Virus attachment protein p12 family DUF1180 PF06679.7 EIW84789.1 - 6.1 6.7 0.0 6.1 6.7 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) Pam17 PF08566.5 EIW84790.1 - 1e-63 214.1 0.0 1.2e-63 213.8 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 SNF2_N PF00176.18 EIW84791.1 - 1.1e-38 132.7 0.0 8e-31 106.9 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW84791.1 - 1.3e-05 24.9 0.0 2.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GntR PF00392.16 EIW84791.1 - 0.0081 15.5 0.0 0.037 13.4 0.0 2.1 2 0 0 2 2 2 1 Bacterial regulatory proteins, gntR family Hyccin PF09790.4 EIW84792.1 - 0.15 10.8 0.1 0.19 10.5 0.1 1.1 1 0 0 1 1 1 0 Hyccin p450 PF00067.17 EIW84793.1 - 2.4e-12 46.1 0.0 2.6e-12 46.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW84794.1 - 5.8e-41 140.4 0.0 7e-41 140.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FdhD-NarQ PF02634.10 EIW84795.1 - 0.09 12.2 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 FdhD/NarQ family Cast PF10174.4 EIW84796.1 - 0.00017 19.7 8.2 0.00024 19.3 5.7 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone SlyX PF04102.7 EIW84796.1 - 0.0029 17.9 11.5 0.99 9.8 0.1 3.5 2 1 0 3 3 3 1 SlyX DUF972 PF06156.8 EIW84796.1 - 0.0031 17.8 5.7 2.1 8.7 2.1 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF972) Baculo_PEP_C PF04513.7 EIW84796.1 - 0.0036 17.1 4.9 0.4 10.5 2.3 2.7 1 1 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Tropomyosin PF00261.15 EIW84796.1 - 0.0044 16.1 10.1 0.0071 15.4 4.5 2.6 2 1 1 3 3 3 2 Tropomyosin Reo_sigmaC PF04582.7 EIW84796.1 - 0.0051 16.0 11.3 0.04 13.0 3.1 2.2 1 1 1 2 2 2 1 Reovirus sigma C capsid protein TBPIP PF07106.8 EIW84796.1 - 0.0086 15.6 9.4 0.25 10.8 3.6 2.4 1 1 0 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Fmp27_WPPW PF10359.4 EIW84796.1 - 0.011 14.2 8.7 0.009 14.4 5.1 1.5 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF948 PF06103.6 EIW84796.1 - 0.018 14.8 5.8 2.5 7.9 0.3 3.3 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.3 EIW84796.1 - 0.019 14.7 9.1 1.2 9.0 4.2 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.2 EIW84796.1 - 0.027 14.3 10.6 0.11 12.3 5.1 2.4 1 1 0 2 2 2 0 Tropomyosin like LolA PF03548.10 EIW84796.1 - 0.027 14.0 0.4 0.91 9.1 0.0 2.5 2 2 0 2 2 2 0 Outer membrane lipoprotein carrier protein LolA Phage_GP20 PF06810.6 EIW84796.1 - 0.036 13.4 7.5 1.8 8.0 0.0 2.4 1 1 1 2 2 2 0 Phage minor structural protein GP20 DASH_Duo1 PF08651.5 EIW84796.1 - 0.04 13.4 2.5 0.076 12.6 0.6 2.3 1 1 1 2 2 2 0 DASH complex subunit Duo1 Fib_alpha PF08702.5 EIW84796.1 - 0.048 13.7 10.7 2.6 8.1 1.9 3.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.3 EIW84796.1 - 0.052 10.8 9.4 0.034 11.5 4.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Laminin_II PF06009.7 EIW84796.1 - 0.053 13.2 8.7 1.4 8.7 2.3 3.2 1 1 1 2 2 2 0 Laminin Domain II Spc7 PF08317.6 EIW84796.1 - 0.059 12.0 12.1 0.051 12.2 4.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Laminin_I PF06008.9 EIW84796.1 - 0.06 12.6 9.5 0.095 11.9 3.7 2.3 1 1 0 2 2 2 0 Laminin Domain I FliJ PF02050.11 EIW84796.1 - 0.068 13.2 7.4 0.046 13.7 3.3 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein HrpB7 PF09486.5 EIW84796.1 - 0.081 12.8 1.2 0.23 11.3 0.3 2.0 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) FlaC_arch PF05377.6 EIW84796.1 - 0.14 12.0 4.1 5.7 6.9 0.1 3.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.4 EIW84796.1 - 0.17 12.0 6.2 2 8.5 1.2 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 IncA PF04156.9 EIW84796.1 - 0.36 10.4 22.2 0.072 12.6 6.4 3.3 2 1 1 3 3 2 0 IncA protein DUF1664 PF07889.7 EIW84796.1 - 0.42 10.4 12.2 0.41 10.4 0.8 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 EIW84796.1 - 0.48 10.6 5.0 21 5.4 0.3 3.4 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein P4Ha_N PF08336.6 EIW84796.1 - 0.51 10.1 6.1 1.2 8.8 0.8 3.1 1 1 2 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region ATG16 PF08614.6 EIW84796.1 - 0.54 10.0 10.4 0.48 10.2 3.9 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Syntaxin-6_N PF09177.6 EIW84796.1 - 0.55 10.6 7.2 18 5.8 0.0 3.1 1 1 3 4 4 4 0 Syntaxin 6, N-terminal Prominin PF05478.6 EIW84796.1 - 0.59 7.5 8.7 0.35 8.3 4.3 1.6 1 1 1 2 2 2 0 Prominin CorA PF01544.13 EIW84796.1 - 0.67 8.9 3.8 1.2 8.1 2.7 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Syntaxin PF00804.20 EIW84796.1 - 0.68 10.1 9.3 1.9 8.7 0.0 3.1 1 1 1 2 2 2 0 Syntaxin Cluap1 PF10234.4 EIW84796.1 - 0.68 9.0 8.6 1.1 8.3 0.7 2.2 1 1 1 2 2 2 0 Clusterin-associated protein-1 Atg14 PF10186.4 EIW84796.1 - 1 8.2 8.6 3.9 6.3 4.6 2.2 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Med9 PF07544.8 EIW84796.1 - 1.1 9.0 7.0 15 5.4 0.2 3.5 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 CENP-F_leu_zip PF10473.4 EIW84796.1 - 1.4 8.7 11.2 5.3 6.8 0.3 2.4 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc24 PF08286.6 EIW84796.1 - 1.8 8.2 7.8 8.8 6.0 2.0 3.3 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 Jnk-SapK_ap_N PF09744.4 EIW84796.1 - 2.3 8.1 8.5 7.5 6.5 3.9 2.5 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF2968 PF11180.3 EIW84796.1 - 3.1 7.1 8.8 0.85 8.9 1.8 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) Pkinase PF00069.20 EIW84797.1 - 1.3e-68 231.0 0.0 1.5e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW84797.1 - 1.6e-42 145.4 0.0 2e-42 145.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EIW84797.1 - 3.9e-15 55.7 0.3 8.7e-15 54.6 0.2 1.6 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EIW84797.1 - 3.8e-08 32.6 0.0 5.2e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIW84797.1 - 1.3e-05 24.3 0.1 2.9e-05 23.2 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW84797.1 - 7e-05 22.6 0.0 0.00057 19.6 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIW84797.1 - 0.0075 15.6 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Transposase_21 PF02992.9 EIW84798.1 - 8.9e-12 44.5 0.0 1.1e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 Sad1_UNC PF07738.8 EIW84799.1 - 3.2e-08 33.4 0.0 4.6e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal WD40 PF00400.27 EIW84804.1 - 0.004 16.9 2.1 0.27 11.1 0.7 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat CNH PF00780.17 EIW84804.1 - 0.15 11.4 0.0 0.38 10.1 0.0 1.7 1 1 0 1 1 1 0 CNH domain HALZ PF02183.13 EIW84804.1 - 0.19 11.5 1.2 0.37 10.5 0.8 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper F-box-like PF12937.2 EIW84805.1 - 2.9e-11 42.9 0.8 5.5e-11 42.0 0.1 1.8 1 1 1 2 2 2 1 F-box-like F-box PF00646.28 EIW84805.1 - 0.0045 16.5 1.1 0.19 11.4 0.0 2.5 2 0 0 2 2 2 2 F-box domain DMRL_synthase PF00885.14 EIW84806.1 - 2.8e-47 160.0 0.1 2.8e-27 95.1 0.0 2.1 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase SRP40_C PF05022.7 EIW84807.1 - 1.4e-21 76.7 2.7 1.5e-21 76.6 1.9 1.0 1 0 0 1 1 1 1 SRP40, C-terminal domain DUF1793 PF08760.6 EIW84808.1 - 2.7e-45 154.3 0.3 5.2e-45 153.3 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1793) Aha1_N PF09229.6 EIW84809.1 - 2.4e-24 85.7 0.0 3.3e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EIW84809.1 - 7.6e-14 51.8 0.1 6.3e-13 48.9 0.0 2.2 2 1 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein Polyketide_cyc2 PF10604.4 EIW84809.1 - 1.7e-05 25.0 1.0 0.00029 21.0 0.0 2.3 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport DUF2360 PF10152.4 EIW84809.1 - 0.082 13.1 3.0 0.27 11.5 1.2 2.1 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) Adeno_PIX PF03955.9 EIW84809.1 - 0.34 11.4 3.7 1.5 9.3 0.0 3.0 3 1 1 4 4 4 0 Adenovirus hexon-associated protein (IX) Ribosomal_60s PF00428.14 EIW84809.1 - 5.1 7.5 8.3 0.93 9.9 2.8 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein ASFV_J13L PF05568.6 EIW84809.1 - 6.9 6.1 8.6 0.34 10.4 1.8 1.9 2 0 0 2 2 2 0 African swine fever virus J13L protein WD40 PF00400.27 EIW84811.1 - 5.7e-29 98.9 22.5 1.2e-06 28.0 0.5 11.7 12 0 0 12 12 12 8 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW84811.1 - 4.5e-08 32.8 0.4 0.012 15.1 0.0 3.7 3 0 0 3 3 3 3 PQQ-like domain PD40 PF07676.7 EIW84811.1 - 1.3e-05 24.7 5.9 21 4.9 0.0 7.8 8 1 0 8 8 8 0 WD40-like Beta Propeller Repeat DUF1513 PF07433.6 EIW84811.1 - 0.00034 19.6 0.1 0.66 8.8 0.0 4.5 3 3 1 5 5 5 1 Protein of unknown function (DUF1513) eIF2A PF08662.6 EIW84811.1 - 0.00041 20.1 0.0 16 5.1 0.0 4.7 4 2 0 4 4 4 1 Eukaryotic translation initiation factor eIF2A Hira PF07569.6 EIW84811.1 - 0.012 14.8 0.0 0.6 9.2 0.0 3.1 1 1 2 3 3 3 0 TUP1-like enhancer of split Nucleoporin_N PF08801.6 EIW84811.1 - 0.012 14.3 0.0 1.4 7.5 0.0 2.7 2 1 1 3 3 3 0 Nup133 N terminal like Proteasome_A_N PF10584.4 EIW84811.1 - 0.016 14.5 10.7 6.1 6.2 0.0 6.5 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature IKI3 PF04762.7 EIW84811.1 - 0.36 8.5 0.0 10 3.7 0.0 2.9 2 1 0 2 2 2 0 IKI3 family F-box-like PF12937.2 EIW84812.1 - 0.0017 18.0 0.3 0.0054 16.4 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW84812.1 - 0.0039 16.7 0.0 0.011 15.3 0.0 1.8 1 0 0 1 1 1 1 F-box domain VRR_NUC PF08774.6 EIW84813.1 - 1.5e-18 66.6 0.0 3.6e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain Hydrolase PF00702.21 EIW84814.1 - 9.2e-13 49.0 2.4 4e-08 33.9 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EIW84814.1 - 8.4e-12 45.6 0.2 3.8e-11 43.5 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EIW84814.1 - 2.6e-10 40.1 0.0 9.8e-10 38.2 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit E1-E2_ATPase PF00122.15 EIW84814.1 - 5.5e-10 38.6 1.4 1.5e-09 37.2 0.0 2.4 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.7 EIW84814.1 - 0.00013 21.6 1.3 0.0048 16.4 0.3 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Septin PF00735.13 EIW84815.1 - 8.9e-115 382.5 1.2 1e-114 382.3 0.8 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EIW84815.1 - 4.7e-08 32.9 0.0 1.3e-07 31.5 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EIW84815.1 - 6.2e-07 28.7 0.0 1.2e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EIW84815.1 - 4.2e-06 26.0 0.0 7.1e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EIW84815.1 - 2.9e-05 23.5 0.4 0.00065 19.1 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EIW84815.1 - 4.8e-05 23.2 0.5 0.11 12.2 0.1 2.4 1 1 0 2 2 2 2 Dynamin family FtsK_SpoIIIE PF01580.13 EIW84815.1 - 0.00015 21.2 0.0 0.0003 20.3 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_10 PF12846.2 EIW84815.1 - 0.00042 19.8 0.0 0.00044 19.8 0.0 1.3 1 1 0 1 1 1 1 AAA-like domain T2SE PF00437.15 EIW84815.1 - 0.00043 19.2 0.1 0.00085 18.2 0.1 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.22 EIW84815.1 - 0.00072 19.8 0.3 0.0014 18.9 0.1 1.7 1 1 0 1 1 1 1 ABC transporter Gtr1_RagA PF04670.7 EIW84815.1 - 0.0011 18.1 0.1 0.0042 16.2 0.0 1.8 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region NB-ARC PF00931.17 EIW84815.1 - 0.0031 16.4 0.1 0.0084 14.9 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA_22 PF13401.1 EIW84815.1 - 0.012 15.7 0.0 0.027 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIW84815.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.1 EIW84815.1 - 0.014 15.2 0.1 0.073 12.9 0.0 2.2 2 1 0 2 2 2 0 AAA domain Miro PF08477.8 EIW84815.1 - 0.021 15.3 0.0 0.062 13.8 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 EIW84815.1 - 0.025 14.9 0.0 0.049 13.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain Ras PF00071.17 EIW84815.1 - 0.025 13.9 0.4 0.23 10.8 0.1 2.4 2 1 0 2 2 2 0 Ras family IIGP PF05049.8 EIW84815.1 - 0.026 13.3 0.2 0.083 11.6 0.0 1.9 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 EIW84815.1 - 0.026 14.0 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 EIW84815.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EIW84815.1 - 0.19 11.4 1.3 0.33 10.7 0.1 1.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 F-box-like PF12937.2 EIW84816.1 - 2.6e-09 36.6 0.1 6.3e-09 35.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like DUF4628 PF15429.1 EIW84817.1 - 0.082 12.3 0.2 0.088 12.2 0.1 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4628) F-box-like PF12937.2 EIW84819.1 - 9e-09 34.9 0.2 4.1e-08 32.8 0.1 2.2 2 0 0 2 2 2 1 F-box-like Glyco_hydro_cc PF11790.3 EIW84822.1 - 5.3e-34 117.6 0.0 6.2e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core YTH PF04146.10 EIW84824.1 - 2.2e-46 156.9 0.0 3.5e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 YT521-B-like domain CALCOCO1 PF07888.6 EIW84824.1 - 0.2 9.8 0.0 0.39 8.9 0.0 1.4 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like UPF0261 PF06792.6 EIW84825.1 - 5.3e-134 446.6 5.9 6.1e-134 446.4 4.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0261) TIM-br_sig_trns PF09370.5 EIW84826.1 - 7.9e-133 441.5 0.5 9.1e-133 441.3 0.4 1.0 1 0 0 1 1 1 1 TIM-barrel signal transduction protein NMO PF03060.10 EIW84826.1 - 6.7e-05 22.1 0.1 0.00011 21.4 0.1 1.5 2 0 0 2 2 2 1 Nitronate monooxygenase WD40 PF00400.27 EIW84827.1 - 1.9e-80 262.0 13.6 2.6e-13 49.3 0.0 7.5 7 1 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EIW84827.1 - 1.9e-09 36.2 8.8 0.0054 14.9 0.0 5.5 2 2 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIW84827.1 - 1.4e-06 27.3 0.7 0.19 10.4 0.2 3.8 1 1 3 4 4 4 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 EIW84827.1 - 0.00073 17.9 0.0 0.56 8.4 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain F-box PF00646.28 EIW84828.1 - 6e-08 32.1 0.2 1.4e-07 30.9 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW84828.1 - 9.8e-06 25.2 0.2 2.1e-05 24.1 0.2 1.6 1 0 0 1 1 1 1 F-box-like F_actin_cap_B PF01115.12 EIW84828.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 F-actin capping protein, beta subunit F-box-like PF12937.2 EIW84829.1 - 2.5e-08 33.5 0.3 7.2e-08 32.0 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIW84830.1 - 5.2e-10 38.8 1.4 1.7e-09 37.2 1.0 2.0 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EIW84830.1 - 0.066 12.9 0.2 0.16 11.7 0.2 1.6 1 0 0 1 1 1 0 F-box-like domain WD40 PF00400.27 EIW84832.1 - 3.5e-21 74.2 13.5 2.4e-07 30.3 0.0 7.1 6 1 0 6 6 6 5 WD domain, G-beta repeat Rax2 PF12768.2 EIW84832.1 - 3e-05 23.3 0.0 0.00071 18.8 0.0 2.3 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Apc4_WD40 PF12894.2 EIW84832.1 - 0.00042 19.7 0.0 19 4.8 0.0 4.2 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain DPPIV_N PF00930.16 EIW84832.1 - 0.0021 16.6 1.1 0.044 12.3 0.5 2.6 2 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region eIF2A PF08662.6 EIW84832.1 - 0.0086 15.7 0.4 0.83 9.3 0.0 2.7 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Vps16_N PF04841.8 EIW84832.1 - 0.068 11.6 0.0 1.3 7.5 0.0 2.1 2 0 0 2 2 2 0 Vps16, N-terminal region GATA PF00320.22 EIW84833.1 - 4.3e-14 51.5 6.0 7.7e-14 50.7 4.2 1.4 1 0 0 1 1 1 1 GATA zinc finger PAS PF00989.19 EIW84833.1 - 0.0029 17.3 0.0 0.0053 16.5 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_8 PF13188.1 EIW84833.1 - 0.0032 17.2 0.0 0.0067 16.2 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_3 PF08447.6 EIW84833.1 - 0.0087 16.1 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EIW84833.1 - 0.011 15.8 0.0 0.026 14.5 0.0 1.7 1 0 0 1 1 1 0 PAS fold PAS_9 PF13426.1 EIW84833.1 - 0.012 15.9 0.0 0.025 14.9 0.0 1.4 1 0 0 1 1 1 0 PAS domain adh_short_C2 PF13561.1 EIW84834.1 - 7.3e-29 101.2 0.1 9.1e-29 100.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIW84834.1 - 4.9e-25 88.3 0.4 8.8e-25 87.5 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW84834.1 - 9.2e-11 41.7 0.1 2.4e-10 40.4 0.1 1.6 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EIW84834.1 - 0.00036 19.5 0.0 0.00047 19.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EIW84834.1 - 0.01 15.2 0.2 0.05 13.0 0.2 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 EIW84834.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Kinesin PF00225.18 EIW84835.1 - 1.4e-100 336.2 7.3 1.5e-55 188.2 0.0 4.5 4 0 0 4 4 4 2 Kinesin motor domain Fib_alpha PF08702.5 EIW84835.1 - 0.00074 19.6 4.1 0.00074 19.6 2.9 11.7 8 4 4 12 12 12 3 Fibrinogen alpha/beta chain family DUF904 PF06005.7 EIW84835.1 - 0.0015 18.8 3.1 0.0015 18.8 2.2 17.0 11 4 6 17 17 17 1 Protein of unknown function (DUF904) ERM PF00769.14 EIW84835.1 - 0.0018 17.8 8.5 0.0018 17.8 5.9 10.5 5 2 5 11 11 11 2 Ezrin/radixin/moesin family TMF_DNA_bd PF12329.3 EIW84835.1 - 0.0023 17.6 3.0 0.0023 17.6 2.1 20.8 10 6 12 23 23 23 5 TATA element modulatory factor 1 DNA binding NIF PF03031.13 EIW84836.1 - 6.3e-22 77.9 0.0 9.9e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 EIW84836.1 - 1.1e-05 24.7 0.0 2.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family NUDIX PF00293.23 EIW84837.1 - 1.4e-18 66.8 0.0 1.4e-13 50.6 0.0 3.1 2 1 0 2 2 2 2 NUDIX domain NUDIX_4 PF14815.1 EIW84837.1 - 0.15 11.4 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 NUDIX domain COesterase PF00135.23 EIW84838.1 - 2.1e-66 224.7 0.4 2.8e-66 224.3 0.3 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EIW84838.1 - 9.4e-13 48.2 0.5 2.4e-12 46.8 0.2 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold PG_binding_1 PF01471.13 EIW84838.1 - 0.0089 15.9 0.0 0.2 11.6 0.0 2.6 2 0 0 2 2 2 1 Putative peptidoglycan binding domain CwfJ_C_1 PF04677.10 EIW84839.1 - 6.7e-29 100.0 0.0 1e-28 99.4 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EIW84839.1 - 1.2e-18 67.3 0.0 3e-18 66.1 0.0 1.6 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 zf-CCHC_2 PF13696.1 EIW84839.1 - 1.2e-15 56.7 17.4 1.1e-05 24.7 1.8 3.6 2 1 1 3 3 3 3 Zinc knuckle zf-CCHC PF00098.18 EIW84839.1 - 2.4e-05 24.0 15.1 0.0016 18.2 0.2 4.0 4 0 0 4 4 4 3 Zinc knuckle TF_Zn_Ribbon PF08271.7 EIW84839.1 - 5.8 6.3 13.2 59 3.0 2.5 3.3 1 1 1 2 2 2 0 TFIIB zinc-binding Aminotran_1_2 PF00155.16 EIW84840.1 - 2.1e-30 105.9 0.0 2.5e-30 105.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Arginase PF00491.16 EIW84841.1 - 1.2e-77 260.9 0.1 1.4e-77 260.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family Arginase PF00491.16 EIW84842.1 - 4.7e-71 239.3 0.2 5.5e-71 239.0 0.1 1.0 1 0 0 1 1 1 1 Arginase family PCI_Csn8 PF10075.4 EIW84845.1 - 4.2e-17 62.2 0.3 8.3e-17 61.2 0.2 1.5 1 1 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EIW84845.1 - 2.5e-05 23.9 0.2 3.2e-05 23.6 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF1681 PF07933.9 EIW84846.1 - 1.2e-52 177.6 0.0 1.4e-52 177.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Glyco_hydro_6 PF01341.12 EIW84847.1 - 8.9e-106 353.6 2.0 1.1e-105 353.4 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Golgin_A5 PF09787.4 EIW84847.1 - 0.21 10.0 0.0 0.33 9.4 0.0 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Nucleoplasmin PF03066.10 EIW84848.1 - 0.16 11.5 0.6 0.24 10.9 0.4 1.3 1 0 0 1 1 1 0 Nucleoplasmin Pkinase PF00069.20 EIW84849.1 - 4.9e-45 153.7 0.0 6e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW84849.1 - 3.2e-19 69.0 0.0 4.1e-19 68.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW84849.1 - 4.4e-09 35.7 0.0 5.4e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW84849.1 - 0.0018 18.0 0.6 0.0047 16.6 0.1 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Tim54 PF11711.3 EIW84851.1 - 6.3e-63 212.6 0.1 8.8e-62 208.8 0.1 2.1 1 1 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Sec63 PF02889.11 EIW84852.1 - 2.4e-28 99.2 0.1 8.1e-24 84.4 0.0 2.3 1 1 1 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EIW84852.1 - 1.7e-24 86.1 0.0 3.6e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EIW84852.1 - 2.1e-07 30.9 0.3 7.6e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EIW84852.1 - 2.4e-07 30.5 0.0 6e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 EIW84852.1 - 0.061 13.5 0.0 0.59 10.3 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain CKS PF01111.14 EIW84853.1 - 9.2e-36 121.5 0.5 1.2e-35 121.1 0.3 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF3822 PF12864.2 EIW84853.1 - 0.077 12.2 0.0 0.092 11.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3822) Phage_holin_3 PF05106.7 EIW84854.1 - 0.071 13.1 1.1 0.15 12.0 0.1 2.0 2 0 0 2 2 2 0 Phage holin family (Lysis protein S) DUF4029 PF13221.1 EIW84854.1 - 0.69 10.3 4.4 0.38 11.1 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4029) Peptidase_M16 PF00675.15 EIW84855.1 - 1.5e-34 118.8 0.3 4.6e-34 117.3 0.2 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EIW84855.1 - 1.3e-22 80.4 0.0 3.7e-11 43.0 0.0 2.6 2 0 0 2 2 2 2 Peptidase M16 inactive domain Rep_fac-A_C PF08646.5 EIW84857.1 - 5.6e-51 172.0 2.8 4.6e-49 165.8 0.9 2.4 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EIW84857.1 - 2.6e-20 72.1 1.2 5.2e-20 71.1 0.8 1.5 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EIW84857.1 - 9.9e-14 50.9 0.1 2.9e-13 49.4 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain DUF4539 PF15072.1 EIW84857.1 - 0.05 13.2 0.1 0.92 9.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4539) HSDR_N PF04313.9 EIW84857.1 - 0.13 11.9 1.6 0.27 10.9 0.1 2.0 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) zf-C2H2 PF00096.21 EIW84857.1 - 0.23 11.8 0.5 0.8 10.1 0.3 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type IDO PF01231.13 EIW84858.1 - 8.2e-96 321.0 0.0 1e-95 320.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 EIW84858.1 - 0.12 10.9 0.0 0.25 9.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1864) ECH_C PF13766.1 EIW84859.1 - 1.1e-33 115.8 0.0 2.8e-33 114.5 0.0 1.7 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EIW84859.1 - 2.6e-23 82.4 0.0 4.3e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family FliG_N PF14842.1 EIW84859.1 - 0.039 14.0 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 FliG N-terminal domain DUF2497 PF10691.4 EIW84859.1 - 0.044 13.7 0.2 2.2 8.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) TilS PF09179.6 EIW84859.1 - 0.12 12.3 0.3 0.46 10.5 0.1 2.1 2 0 0 2 2 2 0 TilS substrate binding domain CAP_GLY PF01302.20 EIW84860.1 - 1.5e-19 69.4 0.5 2.9e-19 68.5 0.3 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.2 EIW84860.1 - 2.1e-15 55.9 12.1 1.3e-05 24.6 0.5 5.3 4 1 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW84860.1 - 3.5e-10 39.4 7.3 0.00011 21.9 0.1 5.4 1 1 5 6 6 6 4 Leucine rich repeat LRR_1 PF00560.28 EIW84860.1 - 1.1e-08 33.8 5.6 0.11 12.6 0.0 7.3 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_9 PF14580.1 EIW84860.1 - 2.2e-08 33.8 0.0 1.4e-07 31.1 0.0 2.2 3 0 0 3 3 3 1 Leucine-rich repeat LRR_7 PF13504.1 EIW84860.1 - 4.9e-06 25.8 10.4 0.19 12.0 0.2 6.8 7 0 0 7 7 7 2 Leucine rich repeat LRR_6 PF13516.1 EIW84860.1 - 8.8e-05 22.1 11.6 3.1 8.1 0.0 7.4 8 0 0 8 8 8 1 Leucine Rich repeat Cep57_CLD PF14073.1 EIW84860.1 - 0.12 12.2 0.3 0.24 11.1 0.0 1.6 2 0 0 2 2 2 0 Centrosome localisation domain of Cep57 Aminotran_5 PF00266.14 EIW84861.1 - 2.3e-97 326.0 0.0 2.7e-97 325.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EIW84861.1 - 0.002 16.4 0.1 0.0029 15.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EIW84861.1 - 0.003 16.6 0.2 0.0072 15.4 0.1 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_hydro_6 PF01341.12 EIW84862.1 - 4.7e-15 55.8 0.1 6e-15 55.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Aldo_ket_red PF00248.16 EIW84863.1 - 2.1e-50 171.1 0.0 2.4e-50 170.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Na_Ca_ex PF01699.19 EIW84865.1 - 8.3e-44 148.5 28.7 6.1e-24 84.2 8.6 2.6 2 1 1 3 3 3 2 Sodium/calcium exchanger protein DUF872 PF05915.7 EIW84865.1 - 0.04 13.7 0.3 0.66 9.8 0.1 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Ins_P5_2-kin PF06090.7 EIW84866.1 - 1.9e-50 171.6 0.0 2.9e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Acyl-CoA_dh_1 PF00441.19 EIW84868.1 - 8.4e-41 139.5 1.3 9.1e-41 139.4 0.2 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EIW84868.1 - 2.7e-34 118.1 0.1 5e-34 117.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EIW84868.1 - 1.4e-16 59.6 0.1 3.2e-16 58.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EIW84868.1 - 1.6e-15 57.5 0.6 3.3e-15 56.5 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 EIW84868.1 - 0.024 14.9 0.0 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal SKIP_SNW PF02731.10 EIW84869.1 - 1.9e-66 222.3 0.9 1.9e-66 222.3 0.6 2.5 3 0 0 3 3 3 1 SKIP/SNW domain SH3_9 PF14604.1 EIW84870.1 - 5.5e-06 25.8 0.0 1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIW84870.1 - 8.4e-05 21.8 0.0 0.00014 21.1 0.0 1.3 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIW84870.1 - 0.00018 20.9 0.0 0.00036 19.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Presenilin PF01080.12 EIW84870.1 - 5.3 5.7 5.7 7.4 5.2 3.9 1.2 1 0 0 1 1 1 0 Presenilin Gtr1_RagA PF04670.7 EIW84871.1 - 9.3e-83 276.9 0.0 1.7e-82 276.0 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EIW84871.1 - 1e-05 25.0 0.0 1.6e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW84871.1 - 0.00011 22.6 0.0 0.00023 21.6 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIW84871.1 - 0.00014 21.7 0.0 0.00032 20.6 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.16 EIW84871.1 - 0.00029 20.1 0.0 0.00082 18.6 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family MAD PF05557.8 EIW84871.1 - 0.016 13.3 0.2 0.023 12.8 0.1 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein HALZ PF02183.13 EIW84871.1 - 0.031 14.0 0.1 0.081 12.6 0.1 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper FTCD_C PF04961.7 EIW84871.1 - 0.055 12.8 0.3 0.1 12.0 0.2 1.4 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase WD40 PF00400.27 EIW84872.1 - 2.2e-41 138.2 13.5 1.4e-07 31.0 0.0 8.1 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EIW84872.1 - 9.2e-17 60.5 1.7 1.7e-16 59.6 1.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW84872.1 - 1.7e-11 43.4 0.5 3.8e-11 42.3 0.3 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EIW84872.1 - 0.0024 16.0 0.1 1.9 6.5 0.0 2.9 3 1 0 3 3 3 2 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EIW84872.1 - 3.2 8.1 10.0 2.6 8.4 0.1 4.8 6 1 0 6 6 6 0 PQQ-like domain DUF3429 PF11911.3 EIW84873.1 - 1.9e-36 125.1 13.0 2.7e-36 124.6 9.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) His_Phos_1 PF00300.17 EIW84875.1 - 3.3e-27 95.5 0.1 9.6e-27 94.0 0.1 1.7 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PFU PF09070.6 EIW84876.1 - 7.8e-44 148.4 0.2 1.6e-43 147.3 0.1 1.6 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.27 EIW84876.1 - 1.5e-36 122.9 24.2 4.1e-07 29.6 0.8 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat PUL PF08324.6 EIW84876.1 - 5.8e-33 113.8 0.0 7.8e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 PUL domain BBS2_Mid PF14783.1 EIW84876.1 - 7.6e-06 25.6 0.0 0.024 14.4 0.0 2.7 2 0 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region HORMA PF02301.13 EIW84877.1 - 1.2e-33 116.3 0.0 2.2e-33 115.5 0.0 1.5 1 0 0 1 1 1 1 HORMA domain PHD PF00628.24 EIW84877.1 - 1e-05 25.0 7.9 1.9e-05 24.2 5.5 1.4 1 0 0 1 1 1 1 PHD-finger Sybindin PF04099.7 EIW84878.1 - 7.3e-41 139.2 0.0 8.4e-41 139.0 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EIW84878.1 - 1.8e-09 37.5 0.0 2e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region TATR PF03430.8 EIW84878.1 - 0.079 11.5 0.0 0.097 11.3 0.0 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator Peptidase_M28 PF04389.12 EIW84879.1 - 4.2e-37 127.6 0.0 6.4e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 RdRP PF05183.7 EIW84880.1 - 1e-157 526.3 0.0 1.8e-157 525.5 0.0 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase PI3_PI4_kinase PF00454.22 EIW84881.1 - 4.1e-36 124.6 0.0 2.1e-35 122.2 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EIW84881.1 - 3.4e-22 78.5 0.0 1.9e-21 76.1 0.0 2.1 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) ACT PF01842.20 EIW84881.1 - 0.091 12.2 0.0 0.23 10.9 0.0 1.7 1 0 0 1 1 1 0 ACT domain Transket_pyr PF02779.19 EIW84882.1 - 5e-38 130.3 0.1 8.5e-38 129.6 0.0 1.4 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EIW84882.1 - 4e-28 97.8 0.0 3.9e-27 94.6 0.0 2.4 2 1 0 2 2 2 1 Transketolase, C-terminal domain WD40 PF00400.27 EIW84883.1 - 4.8e-18 64.2 8.6 0.00022 21.0 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EIW84883.1 - 0.012 13.9 0.0 0.19 10.0 0.0 2.0 1 1 1 2 2 2 0 Cytochrome D1 heme domain Ras PF00071.17 EIW84884.1 - 9.8e-59 197.3 0.4 1.3e-58 196.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW84884.1 - 2e-22 79.9 0.2 3.9e-22 78.9 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIW84884.1 - 3.5e-16 58.9 0.2 4.4e-16 58.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIW84884.1 - 4e-08 32.9 0.3 2.9e-07 30.1 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EIW84884.1 - 1.7e-07 30.6 0.6 2.2e-07 30.2 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EIW84884.1 - 2.8e-07 29.9 0.2 3.8e-07 29.4 0.2 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EIW84884.1 - 3.1e-06 27.1 0.1 1.3e-05 25.1 0.1 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIW84884.1 - 0.00032 19.9 0.5 0.015 14.5 0.4 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Arch_ATPase PF01637.13 EIW84884.1 - 0.0025 17.5 0.0 0.0045 16.7 0.0 1.5 1 1 0 1 1 1 1 Archaeal ATPase Dynamin_N PF00350.18 EIW84884.1 - 0.0045 16.8 0.0 0.86 9.4 0.0 2.5 2 1 0 2 2 2 1 Dynamin family PduV-EutP PF10662.4 EIW84884.1 - 0.03 13.8 1.7 0.26 10.7 1.2 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EIW84884.1 - 0.038 13.8 0.7 0.068 13.0 0.3 1.6 2 1 0 2 2 2 0 AAA domain CPT PF07931.7 EIW84884.1 - 0.043 13.4 0.1 0.11 12.1 0.0 1.7 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.1 EIW84884.1 - 0.067 13.3 0.0 1 9.5 0.0 2.4 1 1 1 2 2 2 0 AAA domain MTHFR PF02219.12 EIW84885.1 - 3.5e-101 338.0 0.0 5e-101 337.5 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase TAP42 PF04177.7 EIW84887.1 - 4.4e-71 239.6 0.0 5.4e-71 239.3 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family Bombesin PF02044.12 EIW84888.1 - 0.14 11.6 0.1 0.27 10.7 0.1 1.5 1 0 0 1 1 1 0 Bombesin-like peptide Macoilin PF09726.4 EIW84888.1 - 2.7 6.1 11.4 4.1 5.5 7.9 1.2 1 0 0 1 1 1 0 Transmembrane protein MCM PF00493.18 EIW84889.1 - 1.2e-135 451.6 0.1 3.4e-134 446.8 0.0 2.1 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EIW84889.1 - 8e-27 94.1 0.4 2.4e-26 92.5 0.2 1.9 2 0 0 2 2 2 1 MCM N-terminal domain AAA_5 PF07728.9 EIW84889.1 - 6e-08 32.5 0.0 1.5e-06 27.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EIW84889.1 - 1.6e-07 30.7 0.1 1.2e-05 24.6 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Mg_chelatase_2 PF13335.1 EIW84889.1 - 6e-05 23.3 1.8 9.8e-05 22.6 0.6 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EIW84889.1 - 0.033 13.7 0.0 0.11 12.1 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EIW84889.1 - 0.066 12.6 0.1 0.71 9.3 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DNA_methylase PF00145.12 EIW84890.1 - 5.2e-46 157.3 0.0 2.3e-22 79.6 0.0 3.4 2 2 0 2 2 2 2 C-5 cytosine-specific DNA methylase DNMT1-RFD PF12047.3 EIW84890.1 - 1.5e-10 40.9 0.4 5.3e-10 39.1 0.0 2.0 2 0 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain BAH PF01426.13 EIW84890.1 - 3.4e-07 30.0 0.7 0.00031 20.4 0.0 3.3 2 1 1 3 3 3 2 BAH domain EF-hand_4 PF12763.2 EIW84891.1 - 0.051 13.3 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand APG9 PF04109.11 EIW84892.1 - 4.3e-157 522.7 0.1 6.1e-157 522.2 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 DUF2231 PF09990.4 EIW84892.1 - 0.13 12.5 1.1 0.66 10.3 0.0 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2231) HMGL-like PF00682.14 EIW84893.1 - 2.7e-60 203.9 0.0 5.1e-60 203.0 0.0 1.5 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EIW84893.1 - 8.6e-42 142.0 0.0 1.5e-19 70.0 0.0 2.5 2 0 0 2 2 2 2 LeuA allosteric (dimerisation) domain tRNA-synt_1c PF00749.16 EIW84894.1 - 1.9e-106 355.3 0.0 2.4e-106 354.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EIW84894.1 - 8.6e-40 136.2 0.2 1.4e-39 135.5 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_2 PF13410.1 EIW84894.1 - 2.6e-05 24.0 0.0 5.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW84894.1 - 5.4e-05 23.5 0.1 0.00018 21.9 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.14 EIW84894.1 - 0.00037 19.7 0.1 0.00071 18.7 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain GST_C PF00043.20 EIW84894.1 - 0.00093 19.1 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pkinase PF00069.20 EIW84896.1 - 2.3e-53 181.0 0.0 3e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW84896.1 - 4.8e-47 160.2 0.0 5.8e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase SAP PF02037.22 EIW84896.1 - 0.0056 16.1 0.1 0.016 14.7 0.1 1.8 1 0 0 1 1 1 1 SAP domain APH PF01636.18 EIW84896.1 - 0.012 15.3 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EIW84896.1 - 0.066 12.0 0.0 0.096 11.5 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Pyr_redox_2 PF07992.9 EIW84897.1 - 7.4e-23 81.4 0.2 1.1e-22 80.8 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW84897.1 - 3.6e-12 46.5 0.4 4.4e-08 33.4 0.0 3.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 EIW84897.1 - 4.1e-11 41.3 0.8 0.00021 20.3 0.4 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EIW84897.1 - 2.9e-09 36.0 0.5 0.0001 21.8 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 EIW84897.1 - 2.8e-08 33.7 0.2 0.0002 21.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EIW84897.1 - 5.7e-08 32.2 0.8 0.0015 18.1 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EIW84897.1 - 3.5e-07 29.2 0.4 0.035 13.4 0.0 2.5 2 0 0 2 2 2 2 EF hand Pyr_redox_3 PF13738.1 EIW84897.1 - 1.2e-05 25.5 0.0 1.1 9.3 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_4 PF12763.2 EIW84897.1 - 0.016 14.9 1.4 2.3 7.9 0.0 2.5 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Toprim PF01751.17 EIW84897.1 - 0.027 14.4 0.1 0.14 12.1 0.0 2.3 1 1 0 1 1 1 0 Toprim domain DUF4147 PF13660.1 EIW84897.1 - 0.046 12.8 0.0 0.24 10.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) TPR_12 PF13424.1 EIW84897.1 - 0.063 13.2 0.1 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Hydrolase_3 PF08282.7 EIW84897.1 - 0.067 12.7 0.1 0.21 11.1 0.0 1.7 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase NAD_binding_7 PF13241.1 EIW84897.1 - 0.11 12.7 0.2 2.1 8.6 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding MFS_1 PF07690.11 EIW84898.1 - 4.4e-29 101.2 31.5 4.4e-29 101.2 21.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3098 PF11297.3 EIW84898.1 - 0.29 10.8 4.7 7.6 6.3 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3098) MACPF PF01823.14 EIW84899.1 - 0.0011 18.6 0.0 0.0018 17.9 0.0 1.3 1 0 0 1 1 1 1 MAC/Perforin domain AAA PF00004.24 EIW84900.1 - 2.4e-14 53.6 0.0 8.7e-14 51.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EIW84900.1 - 8.9e-07 27.9 0.0 0.0013 17.4 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein RuvB_N PF05496.7 EIW84900.1 - 1.6e-05 24.1 0.0 3.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EIW84900.1 - 3.3e-05 23.5 0.0 8.2e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EIW84900.1 - 9.2e-05 22.5 0.0 0.00056 20.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EIW84900.1 - 0.0001 21.7 0.4 0.13 11.5 0.1 2.8 2 1 1 3 3 2 2 AAA domain AAA_17 PF13207.1 EIW84900.1 - 0.00017 22.4 0.0 0.00062 20.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EIW84900.1 - 0.00017 21.4 0.0 0.00034 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW84900.1 - 0.00033 20.6 0.0 0.031 14.2 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EIW84900.1 - 0.001 18.9 0.0 0.0028 17.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EIW84900.1 - 0.0025 17.5 0.0 0.019 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EIW84900.1 - 0.015 14.3 0.0 0.029 13.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_28 PF13521.1 EIW84900.1 - 0.015 15.2 0.0 0.042 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIW84900.1 - 0.021 15.1 0.2 0.075 13.3 0.0 2.1 2 0 0 2 2 1 0 AAA domain NTPase_1 PF03266.10 EIW84900.1 - 0.022 14.4 0.0 0.079 12.6 0.0 1.9 2 0 0 2 2 2 0 NTPase IstB_IS21 PF01695.12 EIW84900.1 - 0.035 13.5 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.7 EIW84900.1 - 0.088 12.4 0.1 0.24 11.0 0.0 1.7 2 0 0 2 2 1 0 NACHT domain DUF258 PF03193.11 EIW84900.1 - 0.14 11.3 0.0 0.29 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP-synt_ab PF00006.20 EIW84901.1 - 2.7e-63 213.3 0.0 4.2e-63 212.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EIW84901.1 - 1.7e-24 86.4 0.9 3.1e-24 85.6 0.6 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EIW84901.1 - 2.1e-22 79.1 1.6 2.1e-22 79.1 1.1 1.9 2 0 0 2 2 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.17 EIW84901.1 - 0.0053 15.6 0.8 0.029 13.2 0.1 2.1 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.1 EIW84901.1 - 0.013 14.9 0.0 0.029 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EIW84901.1 - 0.018 14.7 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase NACHT PF05729.7 EIW84901.1 - 0.024 14.2 0.0 0.052 13.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 EIW84901.1 - 0.028 14.6 0.0 0.34 11.1 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) KaiC PF06745.8 EIW84901.1 - 0.039 13.0 0.1 0.069 12.2 0.1 1.4 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.1 EIW84901.1 - 0.041 14.0 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EIW84901.1 - 0.042 13.5 0.2 1.9 8.2 0.0 2.9 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EIW84901.1 - 0.047 12.8 0.1 0.084 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EIW84901.1 - 0.052 13.5 0.3 0.14 12.1 0.0 1.9 2 1 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 EIW84901.1 - 0.16 12.2 0.6 0.47 10.7 0.1 2.0 2 0 0 2 2 1 0 ABC transporter RNA_helicase PF00910.17 EIW84901.1 - 0.18 11.9 0.0 0.44 10.7 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF1680 PF07944.7 EIW84902.1 - 3.8e-22 78.2 0.0 1.2e-21 76.5 0.0 1.9 2 0 0 2 2 2 1 Putative glycosyl hydrolase of unknown function (DUF1680) Mito_carr PF00153.22 EIW84903.1 - 7.2e-07 28.8 0.0 0.0007 19.2 0.0 2.7 2 0 0 2 2 2 2 Mitochondrial carrier protein CPDase PF07823.6 EIW84904.1 - 1.4e-12 47.5 0.0 3e-12 46.4 0.0 1.6 1 1 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.1 EIW84904.1 - 1.4e-06 28.0 0.2 1.3e-05 24.9 0.2 2.0 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 EIW84904.1 - 0.00023 21.0 0.1 0.017 15.0 0.0 2.3 2 0 0 2 2 2 1 LigT like Phosphoesterase Mito_carr PF00153.22 EIW84906.1 - 1.5e-13 50.2 0.0 4.5e-08 32.6 0.0 2.4 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF1776 PF08643.5 EIW84907.1 - 6.9e-07 28.6 0.0 4.3e-06 26.0 0.0 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Brix PF04427.13 EIW84909.1 - 1.6e-36 125.8 0.1 2.2e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Brix domain KH_1 PF00013.24 EIW84910.1 - 1.1e-38 130.7 9.2 2.2e-14 52.7 0.4 3.2 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EIW84910.1 - 2.5e-29 100.3 14.4 2.5e-09 36.5 1.3 3.7 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EIW84910.1 - 2.8e-15 55.6 5.9 1.9e-05 24.1 0.1 3.4 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EIW84910.1 - 4e-06 26.3 1.9 0.041 13.5 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 EIW84910.1 - 0.0084 15.8 5.2 3.6 7.4 0.0 3.5 3 0 0 3 3 3 2 NusA-like KH domain A_deaminase PF00962.17 EIW84911.1 - 9.7e-49 166.0 0.0 4.4e-48 163.8 0.0 1.9 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 EIW84911.1 - 0.0027 17.6 0.0 0.0056 16.6 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal Asparaginase PF00710.15 EIW84912.1 - 1.3e-120 401.9 0.0 1.7e-120 401.6 0.0 1.1 1 0 0 1 1 1 1 Asparaginase Ank_2 PF12796.2 EIW84912.1 - 7.5e-17 61.4 0.3 6.2e-16 58.5 0.1 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIW84912.1 - 4.7e-15 55.6 0.3 1.1e-07 32.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EIW84912.1 - 3.1e-13 48.8 6.2 4.5e-07 29.3 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.1 EIW84912.1 - 1.3e-09 37.3 4.7 0.00067 19.6 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 EIW84912.1 - 1.5e-08 34.6 2.3 4e-07 30.0 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Trp_syntA PF00290.15 EIW84913.1 - 6e-81 270.7 0.2 8.2e-81 270.3 0.1 1.1 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EIW84913.1 - 1.2e-43 149.5 0.2 2e-43 148.8 0.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme His_biosynth PF00977.16 EIW84913.1 - 0.00029 20.1 0.1 0.00085 18.6 0.0 1.8 1 0 0 1 1 1 1 Histidine biosynthesis protein PcrB PF01884.12 EIW84913.1 - 0.013 14.7 0.1 0.38 9.9 0.1 2.2 2 0 0 2 2 2 0 PcrB family PA PF02225.17 EIW84913.1 - 0.047 13.3 0.2 3.4 7.4 0.0 2.8 2 1 0 2 2 2 0 PA domain LepA_C PF06421.7 EIW84914.1 - 7.8e-41 138.3 0.2 1.4e-40 137.5 0.1 1.4 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus GTP_EFTU PF00009.22 EIW84914.1 - 1.4e-36 125.6 0.0 2.3e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EIW84914.1 - 6.7e-19 67.5 0.0 1.3e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EIW84914.1 - 6.1e-09 35.8 0.1 1.1e-08 35.0 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EIW84914.1 - 2.8e-05 23.8 0.0 5.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.17 EIW84914.1 - 0.00028 20.3 0.0 0.00057 19.3 0.0 1.5 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.13 EIW84914.1 - 0.096 11.9 0.0 0.38 10.0 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B Miro PF08477.8 EIW84914.1 - 0.11 13.0 0.0 0.37 11.3 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein cwf18 PF08315.7 EIW84915.1 - 2.8e-28 98.9 12.4 2.8e-28 98.9 8.6 2.0 2 1 0 2 2 2 1 cwf18 pre-mRNA splicing factor Mo25 PF08569.6 EIW84915.1 - 0.047 12.7 0.3 0.057 12.4 0.2 1.0 1 0 0 1 1 1 0 Mo25-like DUF4238 PF14022.1 EIW84915.1 - 0.86 8.8 3.7 4 6.6 2.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4238) Elongin_A PF06881.6 EIW84916.1 - 3e-17 62.9 0.5 5.2e-17 62.1 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A WD40 PF00400.27 EIW84917.1 - 2.7e-39 131.6 11.7 1.8e-09 37.1 0.2 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat CLTH PF10607.4 EIW84917.1 - 0.00044 19.9 0.0 0.00078 19.1 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain IKI3 PF04762.7 EIW84917.1 - 0.038 11.8 0.3 0.12 10.1 0.0 1.8 2 0 0 2 2 2 0 IKI3 family Coatomer_WDAD PF04053.9 EIW84917.1 - 0.069 11.9 0.2 0.27 9.9 0.0 2.0 2 1 0 2 2 2 0 Coatomer WD associated region Ecl1 PF12855.2 EIW84918.1 - 6.4e-06 25.3 2.2 1.1e-05 24.6 1.5 1.4 1 0 0 1 1 1 1 Life-span regulatory factor Vps54 PF07928.7 EIW84920.1 - 2.9e-50 169.9 1.5 1.6e-49 167.4 1.3 2.1 2 0 0 2 2 2 1 Vps54-like protein DUF2450 PF10475.4 EIW84920.1 - 3e-05 23.0 0.0 0.00011 21.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) GST_C_3 PF14497.1 EIW84921.1 - 0.0008 19.8 0.0 0.0013 19.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EIW84921.1 - 0.023 14.5 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TRAM_LAG1_CLN8 PF03798.11 EIW84922.1 - 3.5e-30 105.0 14.5 5.8e-30 104.3 10.0 1.3 1 0 0 1 1 1 1 TLC domain G-gamma PF00631.17 EIW84923.1 - 2.8e-24 84.6 0.2 3.1e-24 84.4 0.1 1.1 1 0 0 1 1 1 1 GGL domain G-gamma PF00631.17 EIW84925.1 - 7.3e-25 86.5 0.1 8.2e-25 86.3 0.0 1.0 1 0 0 1 1 1 1 GGL domain HALZ PF02183.13 EIW84925.1 - 0.11 12.2 0.2 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Homeobox associated leucine zipper TaqI_C PF12950.2 EIW84926.1 - 0.0083 15.8 0.0 0.011 15.5 0.0 1.2 1 0 0 1 1 1 1 TaqI-like C-terminal specificity domain Cu_bind_like PF02298.12 EIW84926.1 - 0.016 14.9 0.6 0.051 13.3 0.4 1.8 1 1 0 1 1 1 0 Plastocyanin-like domain Copper-bind PF00127.15 EIW84926.1 - 0.039 14.1 0.5 0.079 13.2 0.4 1.5 1 0 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.1 EIW84926.1 - 0.13 12.1 0.0 0.27 11.1 0.0 1.5 1 1 0 1 1 1 0 Cupredoxin-like domain CBF PF03914.12 EIW84927.1 - 1.3e-38 132.0 2.5 2e-38 131.4 0.4 2.2 2 0 0 2 2 2 1 CBF/Mak21 family Myotub-related PF06602.9 EIW84928.1 - 2.3e-125 418.0 0.3 3.5e-125 417.4 0.2 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EIW84928.1 - 0.048 13.9 1.1 0.13 12.4 0.0 2.2 3 0 0 3 3 3 0 Tyrosine phosphatase family PK_C PF02887.11 EIW84928.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Pyruvate kinase, alpha/beta domain S-AdoMet_synt_C PF02773.11 EIW84929.1 - 5.4e-73 243.2 0.2 1e-72 242.3 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EIW84929.1 - 5.4e-48 161.8 0.0 9.4e-48 161.1 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EIW84929.1 - 5.2e-44 148.5 0.1 1e-43 147.5 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain GATase_2 PF00310.16 EIW84930.1 - 5.6e-26 91.1 0.2 5e-20 71.5 0.0 2.2 1 1 1 2 2 2 2 Glutamine amidotransferases class-II Pribosyltran PF00156.22 EIW84930.1 - 5.8e-15 55.1 0.5 1.2e-14 54.1 0.3 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_6 PF13522.1 EIW84930.1 - 2.2e-14 53.5 0.0 4.4e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EIW84930.1 - 3.4e-11 42.9 0.0 5.4e-11 42.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EIW84930.1 - 4.9e-06 25.4 0.0 9.9e-06 24.4 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferases class-II PorB PF11565.3 EIW84930.1 - 0.095 12.9 0.0 0.27 11.4 0.0 1.7 1 0 0 1 1 1 0 Alpha helical Porin B KH_1 PF00013.24 EIW84931.1 - 4.4e-05 23.0 2.6 6.1e-05 22.5 1.0 1.8 2 0 0 2 2 2 1 KH domain DUF3835 PF12927.2 EIW84932.1 - 5.1e-09 36.9 6.9 1.8e-08 35.1 0.5 4.4 3 1 1 4 4 4 2 Domain of unknown function (DUF3835) DUF3186 PF11382.3 EIW84932.1 - 0.0058 15.7 0.9 0.01 14.9 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3186) Plectin PF00681.15 EIW84932.1 - 0.081 12.4 0.1 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 Plectin repeat Glyco_transf_22 PF03901.12 EIW84933.1 - 4.5e-84 282.8 21.1 5.6e-84 282.5 14.6 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF1713 PF08213.6 EIW84934.1 - 1.6e-07 30.8 19.3 2.3e-07 30.3 13.4 1.2 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) DNA_binding_1 PF01035.15 EIW84936.1 - 5.3e-12 45.3 0.1 6.7e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain UQ_con PF00179.21 EIW84937.1 - 1.5e-48 163.7 0.0 1.7e-48 163.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIW84937.1 - 4.8e-05 23.1 0.0 6e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EIW84937.1 - 0.046 13.6 0.6 0.066 13.1 0.4 1.6 1 1 0 1 1 1 0 RWD domain Ribosomal_L7Ae PF01248.21 EIW84938.1 - 1.1e-24 85.7 0.1 1.4e-24 85.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EIW84938.1 - 0.00032 20.5 0.0 0.00036 20.3 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EIW84938.1 - 0.008 15.9 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain CBM_1 PF00734.13 EIW84939.1 - 4.6e-13 48.5 9.6 4.6e-13 48.5 6.7 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain DOMON PF03351.12 EIW84939.1 - 6.6e-05 22.8 0.0 0.00014 21.8 0.0 1.5 1 0 0 1 1 1 1 DOMON domain DUF2048 PF09752.4 EIW84939.1 - 0.016 14.0 0.1 0.023 13.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) FMO-like PF00743.14 EIW84940.1 - 2.8e-43 147.9 0.0 1.9e-32 112.1 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EIW84940.1 - 1.5e-16 61.0 0.0 2.4e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIW84940.1 - 7.7e-07 29.0 3.6 1.5e-05 24.7 0.1 3.5 2 2 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EIW84940.1 - 1.4e-06 28.3 0.0 0.0057 16.5 0.0 2.8 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW84940.1 - 9.7e-05 21.4 0.0 0.0021 17.0 0.0 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EIW84940.1 - 0.0013 18.6 0.6 0.028 14.4 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIW84940.1 - 0.035 13.1 0.6 3.7 6.5 0.1 2.2 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 EIW84940.1 - 0.074 11.5 0.2 13 4.1 0.0 2.9 3 0 0 3 3 3 0 HI0933-like protein Pyr_redox PF00070.22 EIW84940.1 - 0.42 11.0 1.6 4.1 7.8 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW84940.1 - 0.48 9.2 4.2 2.9 6.6 0.0 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Cys_Met_Meta_PP PF01053.15 EIW84941.1 - 3.2e-56 190.2 0.0 1.6e-55 188.0 0.0 1.9 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Proteasome PF00227.21 EIW84942.1 - 2.3e-52 177.0 0.1 2.8e-52 176.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Syja_N PF02383.13 EIW84943.1 - 6.7e-91 304.3 0.0 9.9e-91 303.8 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 EIW84943.1 - 2.2e-24 85.0 0.0 4.4e-24 84.0 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase LIM PF00412.17 EIW84944.1 - 2.2e-16 59.6 25.2 3e-11 43.2 4.7 3.7 4 0 0 4 4 4 3 LIM domain DUF2321 PF10083.4 EIW84944.1 - 1.5 8.2 3.8 2.1 7.8 1.8 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) Fungal_trans PF04082.13 EIW84945.1 - 2.9e-26 91.8 0.0 5.6e-26 90.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW84945.1 - 1e-10 41.3 3.7 2.5e-10 40.0 2.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Polysacc_synt_2 PF02719.10 EIW84945.1 - 0.29 9.9 0.1 0.45 9.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein zf-DHHC PF01529.15 EIW84946.1 - 4.2e-36 123.9 0.3 7.1e-36 123.2 0.2 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase CENP-I PF07778.6 EIW84946.1 - 0.19 9.8 0.8 0.32 9.1 0.3 1.4 2 0 0 2 2 2 0 Mis6 DUF2124 PF09897.4 EIW84946.1 - 0.27 10.9 0.0 0.44 10.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2124) CTP_transf_2 PF01467.21 EIW84947.1 - 1.1e-11 45.0 0.1 1.7e-11 44.4 0.0 1.4 1 1 0 1 1 1 1 Cytidylyltransferase FAD_syn PF06574.7 EIW84947.1 - 0.0025 17.4 0.0 0.0048 16.5 0.0 1.5 1 0 0 1 1 1 1 FAD synthetase Lipase_3 PF01764.20 EIW84948.1 - 2.9e-07 30.1 0.0 6.8e-07 28.9 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EIW84948.1 - 0.0057 16.4 0.0 0.0091 15.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 EIW84948.1 - 0.016 14.9 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_6 PF12697.2 EIW84948.1 - 0.03 14.1 0.1 0.048 13.5 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EIW84948.1 - 0.038 13.5 0.0 0.08 12.5 0.0 1.4 2 0 0 2 2 2 0 PGAP1-like protein Amidohydro_1 PF01979.15 EIW84949.1 - 7.7e-38 130.9 0.1 1.1e-37 130.5 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EIW84949.1 - 3e-07 30.0 0.4 0.00066 18.9 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EIW84949.1 - 7.3e-06 25.7 0.0 1.8e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 EIW84949.1 - 0.0042 16.0 0.1 0.014 14.3 0.0 1.8 1 1 1 2 2 2 1 Adenosine/AMP deaminase Amidohydro_4 PF13147.1 EIW84949.1 - 0.041 13.9 0.1 0.21 11.6 0.0 2.1 2 1 0 2 2 2 0 Amidohydrolase mRNA_cap_enzyme PF01331.14 EIW84950.1 - 1.7e-47 161.5 0.0 2.3e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EIW84950.1 - 8.3e-16 58.2 0.0 2.1e-15 56.9 0.0 1.7 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EIW84950.1 - 1.6e-09 37.4 0.0 1.3e-07 31.1 0.0 2.4 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Skp1 PF01466.14 EIW84951.1 - 1.5e-39 133.8 1.2 2.4e-39 133.2 0.9 1.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EIW84951.1 - 2.1e-23 82.1 0.3 5.7e-23 80.7 0.1 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.26 EIW84951.1 - 0.0003 20.7 0.0 0.013 15.5 0.0 2.2 2 0 0 2 2 2 1 BTB/POZ domain DUF4375 PF14300.1 EIW84951.1 - 0.16 11.9 0.5 0.88 9.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4375) Ribosomal_L27 PF01016.14 EIW84952.1 - 7.6e-32 108.9 0.6 1e-31 108.5 0.4 1.2 1 0 0 1 1 1 1 Ribosomal L27 protein DUF3074 PF11274.3 EIW84953.1 - 1.1e-36 126.2 0.1 1.3e-36 125.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) START PF01852.14 EIW84953.1 - 4.5e-05 22.8 0.0 5.2e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 START domain Gln-synt_C PF00120.19 EIW84954.1 - 6.5e-54 182.7 0.0 1.5e-53 181.6 0.0 1.6 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain WD40 PF00400.27 EIW84955.1 - 5.3e-07 29.2 0.2 0.046 13.6 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat RCC1 PF00415.13 EIW84957.1 - 2.2e-22 79.0 14.8 5.3e-06 26.5 0.0 7.4 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EIW84957.1 - 5.1e-09 35.5 26.4 1.3e-06 27.8 0.2 6.6 6 0 0 6 6 6 2 Regulator of chromosome condensation (RCC1) repeat NHL PF01436.16 EIW84957.1 - 0.039 13.9 0.3 18 5.5 0.0 3.0 2 0 0 2 2 2 0 NHL repeat Spc24 PF08286.6 EIW84958.1 - 1.5e-12 47.2 0.6 4.1e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 Spectrin PF00435.16 EIW84958.1 - 0.015 15.5 0.5 4.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Spectrin repeat APG6 PF04111.7 EIW84958.1 - 0.049 12.6 0.7 0.075 12.0 0.5 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Ndc1_Nup PF09531.5 EIW84958.1 - 0.12 10.8 0.2 0.13 10.6 0.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CAF1A PF12253.3 EIW84959.1 - 2.7e-20 72.2 6.8 6.5e-20 71.0 4.7 1.7 1 0 0 1 1 1 1 Chromatin assembly factor 1 subunit A RST PF12174.3 EIW84959.1 - 0.0023 17.6 0.0 0.0051 16.5 0.0 1.5 1 0 0 1 1 1 1 RCD1-SRO-TAF4 (RST) plant domain DUF4407 PF14362.1 EIW84959.1 - 1.1 8.1 5.8 1.8 7.4 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA PF00004.24 EIW84960.1 - 8.6e-15 55.1 0.0 1.9e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EIW84960.1 - 1e-11 44.7 0.0 9.7e-11 41.5 0.0 2.1 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EIW84960.1 - 7.7e-09 34.7 0.0 1.5e-05 23.8 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein Rep_fac_C PF08542.6 EIW84960.1 - 1.4e-08 34.6 0.0 3e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.1 EIW84960.1 - 8.4e-08 32.4 0.0 2.2e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW84960.1 - 1.4e-05 24.7 0.0 4.6e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EIW84960.1 - 2e-05 24.2 0.0 2.5e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW84960.1 - 4.4e-05 23.5 0.0 0.00028 20.9 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EIW84960.1 - 7.5e-05 22.6 0.0 0.00023 21.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EIW84960.1 - 0.00025 20.1 0.0 0.00061 18.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EIW84960.1 - 0.00036 20.2 0.0 0.0013 18.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EIW84960.1 - 0.00071 19.2 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EIW84960.1 - 0.0024 16.9 0.0 0.0039 16.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EIW84960.1 - 0.0025 17.4 0.0 0.01 15.4 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EIW84960.1 - 0.003 17.0 0.1 0.15 11.4 0.0 2.3 1 1 0 2 2 2 1 AAA-like domain Mg_chelatase PF01078.16 EIW84960.1 - 0.0034 16.5 0.0 0.08 12.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EIW84960.1 - 0.0045 16.4 0.0 0.011 15.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW84960.1 - 0.012 16.4 0.0 0.029 15.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EIW84960.1 - 0.019 14.4 0.0 0.046 13.1 0.0 1.6 2 0 0 2 2 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 EIW84960.1 - 0.023 14.1 0.1 0.4 10.1 0.0 2.2 1 1 1 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 EIW84960.1 - 0.027 14.3 0.0 0.088 12.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EIW84960.1 - 0.028 14.3 0.0 0.078 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EIW84960.1 - 0.032 14.0 0.0 0.071 12.9 0.0 1.6 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_2 PF07724.9 EIW84960.1 - 0.042 13.7 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_23 PF13476.1 EIW84960.1 - 0.044 14.1 0.0 0.057 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 EIW84960.1 - 0.056 12.9 0.1 0.58 9.6 0.0 2.2 1 1 0 2 2 2 0 DEAD/DEAH box helicase PhoH PF02562.11 EIW84960.1 - 0.072 12.3 0.0 2.4 7.3 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein DUF815 PF05673.8 EIW84960.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 EIW84960.1 - 0.13 12.5 0.0 0.26 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EIW84960.1 - 0.16 12.1 0.0 0.32 11.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase HSP70 PF00012.15 EIW84961.1 - 8.2e-243 806.7 7.1 1e-242 806.4 4.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIW84961.1 - 4.1e-17 61.7 0.9 4.4e-16 58.3 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 EIW84961.1 - 0.0088 14.9 0.3 0.074 11.8 0.1 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.15 EIW84961.1 - 0.011 15.0 0.2 1.6 7.9 0.0 2.6 2 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.6 EIW84961.1 - 0.017 14.0 0.0 0.039 12.8 0.0 1.6 1 0 0 1 1 1 0 StbA protein FGGY_C PF02782.11 EIW84961.1 - 0.028 14.0 0.0 0.065 12.8 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain RE_CfrBI PF09516.5 EIW84961.1 - 0.059 12.2 0.6 0.22 10.3 0.0 2.0 2 0 0 2 2 2 0 CfrBI restriction endonuclease Hydantoinase_A PF01968.13 EIW84961.1 - 0.07 12.2 1.6 0.14 11.2 0.1 2.2 3 0 0 3 3 3 0 Hydantoinase/oxoprolinase DUF406 PF04175.7 EIW84961.1 - 0.11 13.0 1.0 0.45 11.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF406) Ribosomal_S2 PF00318.15 EIW84962.1 - 4.7e-49 166.4 0.0 1.7e-46 158.1 0.0 2.1 1 1 0 1 1 1 1 Ribosomal protein S2 Chorismate_bind PF00425.13 EIW84963.1 - 3.4e-89 298.5 0.0 5.7e-89 297.8 0.0 1.4 1 0 0 1 1 1 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EIW84963.1 - 3.3e-29 101.6 0.0 4.7e-28 97.9 0.0 2.3 2 0 0 2 2 2 1 Anthranilate synthase component I, N terminal region SHQ1 PF04925.10 EIW84964.1 - 2.3e-46 157.6 0.2 4.1e-45 153.5 0.0 2.5 2 1 0 2 2 2 1 SHQ1 protein PIH1 PF08190.7 EIW84964.1 - 1.4e-05 24.7 0.0 3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 pre-RNA processing PIH1/Nop17 Nuc_sug_transp PF04142.10 EIW84965.1 - 2.8e-09 36.4 0.7 3.8e-09 36.0 0.5 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EIW84965.1 - 1.6e-06 28.1 22.5 2e-05 24.6 2.0 2.8 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EIW84965.1 - 1.9e-06 27.0 6.7 3.3e-06 26.2 4.6 1.3 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EIW84965.1 - 4.1e-06 26.9 2.8 4.1e-06 26.9 2.0 3.0 2 1 0 2 2 2 1 Multidrug resistance efflux transporter TPT PF03151.11 EIW84965.1 - 9.3e-05 22.1 17.6 0.0051 16.4 0.4 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family CBP4 PF07960.6 EIW84966.1 - 1.8e-05 24.3 0.0 4.2e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 CBP4 Arrestin_C PF02752.17 EIW84966.1 - 0.00017 21.7 0.0 0.00073 19.6 0.0 2.0 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain zf-C3HC4_3 PF13920.1 EIW84967.1 - 0.23 11.1 8.0 0.4 10.3 5.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW84967.1 - 1.2 9.2 10.8 2 8.4 7.5 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) E1-E2_ATPase PF00122.15 EIW84968.1 - 8.6e-65 217.9 6.3 8.6e-65 217.9 4.3 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EIW84968.1 - 2.2e-45 154.4 8.6 2.2e-45 154.4 6.0 2.2 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EIW84968.1 - 3.3e-33 115.9 0.1 1.4e-31 110.5 0.0 3.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EIW84968.1 - 1.3e-21 75.8 0.2 7.9e-21 73.2 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EIW84968.1 - 2.9e-21 75.2 0.0 5.6e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EIW84968.1 - 5e-13 49.6 0.4 1.7e-12 47.8 0.3 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EIW84968.1 - 1.2e-06 28.3 1.5 5.9e-06 26.0 0.9 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EIW84968.1 - 0.011 15.9 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DPBB_1 PF03330.13 EIW84969.1 - 5.1e-07 29.6 0.1 8.6e-07 28.8 0.1 1.5 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIW84969.1 - 0.029 14.0 0.0 0.032 13.8 0.0 1.1 1 0 0 1 1 1 0 Barwin family Paramyxo_ncap PF00973.14 EIW84971.1 - 0.094 11.3 2.3 0.12 11.0 1.6 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein SR-25 PF10500.4 EIW84971.1 - 0.41 10.0 16.8 0.021 14.3 7.8 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ADH_zinc_N_2 PF13602.1 EIW84972.1 - 1.3e-20 74.5 0.0 2.7e-20 73.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EIW84972.1 - 2.7e-12 46.3 0.0 4.5e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW84972.1 - 0.0047 16.6 0.0 0.033 13.9 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain CRM1_C PF08767.6 EIW84973.1 - 9.7e-132 438.7 5.7 1.3e-131 438.2 0.0 3.3 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 EIW84973.1 - 1.8e-41 141.5 7.9 1.1e-40 138.9 5.5 2.5 1 0 0 1 1 1 1 Exportin 1-like protein IBN_N PF03810.14 EIW84973.1 - 6.1e-13 48.4 0.1 3.1e-12 46.2 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain PUA PF01472.15 EIW84974.1 - 9.7e-15 54.0 0.0 1.5e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 PUA domain SRR1 PF07985.7 EIW84975.1 - 1.9e-15 56.4 0.0 3.3e-15 55.7 0.0 1.4 1 0 0 1 1 1 1 SRR1 TPR_11 PF13414.1 EIW84977.1 - 2.1e-27 94.5 24.1 3.1e-09 36.3 0.4 8.5 5 2 3 8 8 8 6 TPR repeat TPR_1 PF00515.23 EIW84977.1 - 1.3e-22 78.3 10.2 5.1e-08 32.2 0.3 8.6 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_2 PF07719.12 EIW84977.1 - 5.4e-21 72.7 17.8 0.0002 21.0 0.2 10.0 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_16 PF13432.1 EIW84977.1 - 2.5e-17 63.0 29.7 1.4e-07 32.0 0.2 8.5 6 3 2 8 8 8 3 Tetratricopeptide repeat TPR_8 PF13181.1 EIW84977.1 - 3.8e-16 57.5 0.2 0.0013 18.3 0.1 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 EIW84977.1 - 9e-16 56.7 6.7 0.12 12.6 0.0 7.5 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 EIW84977.1 - 5.7e-15 55.0 18.0 8.7e-06 25.5 0.1 8.0 5 2 3 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 EIW84977.1 - 1.7e-14 53.9 16.3 0.0013 18.9 0.0 7.8 8 2 1 9 9 8 5 Tetratricopeptide repeat Apc3 PF12895.2 EIW84977.1 - 9.4e-14 51.3 20.0 2e-08 34.2 3.5 5.6 5 2 1 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EIW84977.1 - 3.4e-09 36.5 23.5 0.13 12.9 0.1 9.6 6 1 4 10 10 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 EIW84977.1 - 1.2e-06 28.5 18.3 0.38 11.3 0.0 9.5 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_9 PF13371.1 EIW84977.1 - 1.3e-06 28.1 10.8 0.0028 17.4 0.1 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIW84977.1 - 0.0028 17.3 8.1 6.5 6.8 0.0 6.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.1 EIW84977.1 - 0.083 11.9 0.1 0.083 11.9 0.1 4.4 2 2 3 5 5 5 0 Tetratricopeptide repeat Cpn60_TCP1 PF00118.19 EIW84978.1 - 4.2e-140 467.5 9.4 4.8e-140 467.3 6.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Sua5_yciO_yrdC PF01300.13 EIW84978.1 - 0.0039 16.4 0.1 0.01 15.0 0.0 1.8 2 0 0 2 2 2 1 Telomere recombination Rhodanese PF00581.15 EIW84979.1 - 8e-15 55.1 0.0 1.5e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Lipase_GDSL_2 PF13472.1 EIW84980.1 - 1.7e-31 109.7 0.1 2e-31 109.4 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EIW84980.1 - 6.1e-23 81.8 0.0 8.9e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EIW84980.1 - 0.0047 16.6 0.0 0.007 16.1 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family tRNA_int_endo PF01974.12 EIW84981.1 - 7.3e-13 48.1 0.0 1.3e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain EI24 PF07264.6 EIW84982.1 - 3e-33 115.0 14.8 4.8e-33 114.4 10.2 1.3 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Linker_histone PF00538.14 EIW84983.1 - 3.2e-15 55.9 0.0 3.2e-15 55.9 0.0 2.2 3 0 0 3 3 3 1 linker histone H1 and H5 family RF-1 PF00472.15 EIW84984.1 - 3.1e-25 88.1 5.0 6.6e-25 87.1 3.5 1.5 1 0 0 1 1 1 1 RF-1 domain Peptidase_S49_N PF08496.5 EIW84984.1 - 1.5 8.6 5.2 2.8 7.6 3.6 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CAP_N PF01213.14 EIW84985.1 - 5.6e-96 321.4 0.2 7.8e-96 321.0 0.1 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EIW84985.1 - 1.6e-57 193.2 6.8 2.4e-57 192.7 4.7 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EIW84985.1 - 0.0089 15.4 5.1 0.017 14.5 3.5 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C Imm-NTF2-2 PF15631.1 EIW84985.1 - 0.11 12.5 0.0 0.35 10.8 0.0 1.8 1 0 0 1 1 1 0 NTF2 fold immunity protein UQ_con PF00179.21 EIW84987.1 - 7.5e-42 142.0 0.1 8.5e-42 141.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIW84987.1 - 0.00021 21.0 0.0 0.00024 20.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EIW84987.1 - 0.023 14.4 0.0 0.037 13.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 EIW84987.1 - 0.044 13.6 0.0 0.052 13.4 0.0 1.3 1 0 0 1 1 1 0 RWD domain BTB PF00651.26 EIW84990.1 - 0.00011 22.1 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain CKS PF01111.14 EIW84990.1 - 0.035 13.9 0.0 0.24 11.2 0.0 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase regulatory subunit Nt_Gln_amidase PF09764.4 EIW84991.1 - 1.8e-48 164.2 0.1 2.3e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 N-terminal glutamine amidase ATP12 PF07542.6 EIW84993.1 - 1.2e-40 138.2 0.1 1.9e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein MutS_V PF00488.16 EIW84994.1 - 2.7e-85 285.5 0.0 4.8e-85 284.7 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EIW84994.1 - 5.7e-37 127.4 1.1 5.7e-37 127.4 0.8 2.1 3 0 0 3 3 3 1 MutS domain III MutS_I PF01624.15 EIW84994.1 - 1.1e-13 51.1 0.1 8.8e-07 28.9 0.0 2.6 1 1 1 2 2 2 2 MutS domain I MutS_II PF05188.12 EIW84994.1 - 2.6e-08 33.9 0.8 1.2e-07 31.8 0.0 2.5 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.13 EIW84994.1 - 3.3e-08 33.5 0.5 1.1e-07 31.9 0.3 1.9 1 0 0 1 1 1 1 MutS family domain IV DNA_pol_phi PF04931.8 EIW84995.1 - 1.8e-61 207.9 23.8 1.8e-61 207.9 16.5 2.8 2 1 0 2 2 2 1 DNA polymerase phi MarR_2 PF12802.2 EIW84996.1 - 0.029 14.0 0.3 0.13 11.9 0.1 2.2 2 0 0 2 2 2 0 MarR family Zn_Tnp_IS91 PF14319.1 EIW84996.1 - 0.36 10.3 2.3 0.61 9.6 1.6 1.3 1 0 0 1 1 1 0 Transposase zinc-binding domain LETM1 PF07766.8 EIW84997.1 - 9.1e-99 329.8 0.4 9.1e-99 329.8 0.2 2.1 2 0 0 2 2 2 1 LETM1-like protein SAP PF02037.22 EIW84997.1 - 3e-05 23.4 0.1 0.035 13.6 0.0 3.9 3 0 0 3 3 3 1 SAP domain EF-hand_1 PF00036.27 EIW84997.1 - 0.0029 16.7 0.1 0.13 11.6 0.0 3.4 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 EIW84997.1 - 0.0065 16.5 0.0 0.07 13.2 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EIW84997.1 - 0.0069 16.1 0.0 3.9 7.6 0.0 4.0 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.1 EIW84997.1 - 0.04 13.5 0.7 0.21 11.2 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain pair 2OG-FeII_Oxy_2 PF13532.1 EIW84998.1 - 2.2e-34 118.9 0.0 1.1e-31 110.2 0.0 2.4 2 0 0 2 2 2 2 2OG-Fe(II) oxygenase superfamily SHR3_chaperone PF08229.6 EIW84999.1 - 1.5e-24 86.0 0.0 3e-24 85.0 0.0 1.4 1 1 0 1 1 1 1 ER membrane protein SH3 DUF4094 PF13334.1 EIW84999.1 - 0.0075 16.6 0.4 0.021 15.2 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4094) Oligomerisation PF02410.10 EIW85000.1 - 0.00049 20.0 0.0 0.00077 19.4 0.0 1.2 1 0 0 1 1 1 1 Oligomerisation domain G-patch PF01585.18 EIW85003.1 - 4.1e-07 29.6 3.1 1.3e-06 28.1 2.1 1.9 1 0 0 1 1 1 1 G-patch domain FAD_binding_2 PF00890.19 EIW85004.1 - 1.3e-127 426.1 3.0 1.6e-127 425.8 2.1 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EIW85004.1 - 2e-47 160.2 1.0 3.1e-47 159.6 0.7 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EIW85004.1 - 2.5e-07 30.7 0.0 0.0013 18.6 0.1 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIW85004.1 - 5.1e-06 25.5 1.3 0.0045 15.9 1.5 2.5 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 EIW85004.1 - 1.9e-05 23.8 0.1 0.032 13.3 0.0 2.9 3 0 0 3 3 3 2 Thi4 family DAO PF01266.19 EIW85004.1 - 3.7e-05 22.8 0.3 0.0013 17.7 0.1 2.3 1 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EIW85004.1 - 0.0062 15.6 0.1 0.011 14.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EIW85004.1 - 0.018 13.5 2.1 0.15 10.5 0.5 2.9 4 0 0 4 4 4 0 HI0933-like protein Pyr_redox_3 PF13738.1 EIW85004.1 - 0.12 12.4 0.2 1.5 8.8 0.1 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RabGAP-TBC PF00566.13 EIW85005.1 - 3.5e-30 105.0 0.0 5.8e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain HSP70 PF00012.15 EIW85006.1 - 2.4e-273 907.6 4.5 2.7e-273 907.4 3.2 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EIW85006.1 - 6.3e-15 54.5 0.0 1.1e-13 50.4 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EIW85006.1 - 0.0046 16.0 0.2 0.022 13.8 0.2 2.1 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase FGGY_C PF02782.11 EIW85006.1 - 0.0053 16.3 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EIW85006.1 - 0.016 15.0 1.0 2.5 7.9 0.1 3.2 2 2 0 2 2 2 0 Cell division protein FtsA AAA_23 PF13476.1 EIW85006.1 - 1.5 9.1 10.4 0.15 12.3 3.3 2.0 2 1 0 2 2 2 0 AAA domain B56 PF01603.15 EIW85007.1 - 3.2e-170 566.1 4.8 3.8e-170 565.9 3.3 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Citrate_synt PF00285.16 EIW85009.1 - 2.6e-99 332.3 0.0 3.3e-99 331.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase XH PF03469.9 EIW85009.1 - 0.00091 18.8 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 XH domain Sec66 PF09802.4 EIW85010.1 - 3.3e-53 179.9 0.0 3.8e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 SKG6 PF08693.5 EIW85010.1 - 0.026 13.8 2.5 0.043 13.1 1.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain USP7_ICP0_bdg PF12436.3 EIW85011.1 - 3.7e-83 278.5 1.0 1.2e-82 276.9 0.2 2.2 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EIW85011.1 - 6.1e-69 231.7 8.4 5.7e-66 222.0 1.6 3.6 3 1 1 4 4 4 3 Ubiquitin-specific protease C-terminal UCH PF00443.24 EIW85011.1 - 1e-56 192.0 0.1 1.8e-56 191.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW85011.1 - 6.1e-31 107.9 0.0 9.3e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EIW85011.1 - 5.9e-08 32.9 0.2 5.8e-06 26.5 0.0 3.7 3 2 0 3 3 3 1 MATH domain UN_NPL4 PF11543.3 EIW85011.1 - 0.012 15.9 0.3 4.8 7.5 0.0 3.3 3 0 0 3 3 3 0 Nuclear pore localisation protein NPL4 DNA_primase_lrg PF04104.9 EIW85012.1 - 3.2e-82 275.7 0.0 4.3e-82 275.2 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit CDP-OH_P_transf PF01066.16 EIW85013.1 - 2.8e-12 46.7 3.9 5.9e-12 45.7 2.7 1.5 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase 7TMR-DISM_7TM PF07695.6 EIW85013.1 - 0.025 14.2 0.1 0.039 13.6 0.1 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling SMC_Nse1 PF07574.8 EIW85014.1 - 1.1e-28 100.2 0.0 9.5e-27 93.9 0.0 2.1 1 1 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EIW85014.1 - 1.2e-07 31.6 13.4 2.6e-07 30.5 8.2 2.1 2 0 0 2 2 2 1 RING-like domain zf-RING_2 PF13639.1 EIW85014.1 - 6.6e-05 22.6 11.2 0.00012 21.8 7.8 1.4 1 0 0 1 1 1 1 Ring finger domain Baculo_RING PF05883.6 EIW85014.1 - 0.0034 17.2 0.8 0.0063 16.3 0.5 1.4 1 0 0 1 1 1 1 Baculovirus U-box/Ring-like domain zf-HC5HC2H PF13771.1 EIW85014.1 - 0.0066 16.5 4.9 0.014 15.5 3.4 1.5 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-C3HC4_2 PF13923.1 EIW85014.1 - 0.018 15.0 12.0 0.03 14.3 8.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-HC5HC2H_2 PF13832.1 EIW85014.1 - 0.046 13.7 3.3 0.085 12.8 2.3 1.4 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-C3HC4_3 PF13920.1 EIW85014.1 - 0.079 12.6 9.5 0.13 11.9 6.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW85014.1 - 0.23 11.1 12.1 0.38 10.5 8.4 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EIW85014.1 - 0.63 9.7 11.8 1.2 8.8 8.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2175 PF09943.4 EIW85014.1 - 0.82 9.7 4.0 1.8 8.6 2.8 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) C1_1 PF00130.17 EIW85014.1 - 1.1 9.0 8.2 0.69 9.6 4.5 1.6 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_4 PF14570.1 EIW85014.1 - 1.7 8.3 9.3 3 7.4 6.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain AAA PF00004.24 EIW85015.1 - 8.1e-36 123.1 0.0 2.1e-35 121.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EIW85015.1 - 2.8e-05 24.1 4.5 0.0028 17.6 0.0 4.3 4 1 1 6 6 5 1 AAA ATPase domain AAA_17 PF13207.1 EIW85015.1 - 4.8e-05 24.1 0.1 0.00042 21.1 0.0 2.7 3 1 0 3 3 1 1 AAA domain AAA_11 PF13086.1 EIW85015.1 - 0.00016 21.3 0.1 0.00054 19.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EIW85015.1 - 0.00057 19.6 0.1 0.003 17.3 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EIW85015.1 - 0.00065 19.8 0.3 0.014 15.5 0.0 2.9 2 1 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EIW85015.1 - 0.0018 17.7 0.0 0.065 12.6 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.1 EIW85015.1 - 0.0021 17.9 0.0 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIW85015.1 - 0.0054 16.4 0.1 0.0054 16.4 0.0 3.5 3 0 0 3 3 3 1 Part of AAA domain RuvB_N PF05496.7 EIW85015.1 - 0.025 13.6 0.0 0.054 12.5 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EIW85015.1 - 0.049 13.6 0.0 0.049 13.6 0.0 2.6 4 0 0 4 4 2 0 AAA domain Rep_4 PF05797.6 EIW85015.1 - 0.053 12.2 1.9 2 7.0 0.2 2.8 3 0 0 3 3 3 0 Yeast trans-acting factor (REP1/REP2) AAA_14 PF13173.1 EIW85015.1 - 0.056 13.3 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EIW85015.1 - 0.075 12.6 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 EIW85015.1 - 0.086 12.2 0.4 2.8 7.2 0.1 2.9 2 1 1 3 3 3 0 AAA domain TIP49 PF06068.8 EIW85015.1 - 0.13 10.9 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_18 PF13238.1 EIW85015.1 - 0.14 12.4 0.0 0.14 12.4 0.0 2.3 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.17 EIW85015.1 - 0.17 12.0 0.0 0.47 10.6 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.10 EIW85015.1 - 0.33 9.5 0.0 0.52 8.9 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein CDP-OH_P_transf PF01066.16 EIW85016.1 - 4.8e-19 68.5 3.8 4.8e-19 68.5 2.6 1.7 1 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Cys_Met_Meta_PP PF01053.15 EIW85017.1 - 6e-144 479.0 0.0 6.8e-144 478.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EIW85017.1 - 6.1e-13 48.5 0.8 8.9e-13 48.0 0.1 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EIW85017.1 - 1.4e-10 40.6 0.0 2.3e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EIW85017.1 - 2.5e-08 33.0 1.2 3.9e-08 32.4 0.1 1.8 2 1 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EIW85017.1 - 1.8e-07 30.5 0.0 5e-07 29.1 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase SelA PF03841.8 EIW85017.1 - 0.00027 19.7 0.2 0.00077 18.3 0.1 1.7 1 1 0 1 1 1 1 L-seryl-tRNA selenium transferase GDC-P PF02347.11 EIW85017.1 - 0.0037 16.0 0.0 0.0068 15.1 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 EIW85017.1 - 0.0042 15.4 0.3 0.0074 14.6 0.2 1.3 1 1 0 1 1 1 1 Methionine gamma-lyase Radical_SAM PF04055.16 EIW85017.1 - 0.089 12.9 0.0 2.8 8.1 0.0 2.2 2 0 0 2 2 2 0 Radical SAM superfamily Syntaxin PF00804.20 EIW85018.1 - 2.9e-16 59.4 8.7 1.2e-15 57.5 2.1 2.3 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.14 EIW85018.1 - 8.6e-14 50.9 2.6 8.6e-14 50.9 1.8 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.1 EIW85018.1 - 3.8e-05 23.6 6.5 3.8e-05 23.6 4.5 2.4 2 1 0 2 2 2 1 Syntaxin-like protein ACC_epsilon PF13822.1 EIW85018.1 - 0.006 16.9 0.2 0.006 16.9 0.1 2.6 3 0 0 3 3 2 1 Acyl-CoA carboxylase epsilon subunit Peptidase_M64 PF09471.5 EIW85018.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.5 1 0 0 1 1 1 0 IgA Peptidase M64 Spectrin PF00435.16 EIW85018.1 - 0.023 14.9 7.0 0.65 10.3 0.0 3.4 3 1 0 3 3 3 0 Spectrin repeat DUF4094 PF13334.1 EIW85018.1 - 0.023 15.0 2.2 3.6 8.0 0.0 3.9 3 2 1 4 4 4 0 Domain of unknown function (DUF4094) MCPsignal PF00015.16 EIW85018.1 - 0.077 12.5 12.1 0.076 12.5 1.9 2.5 1 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF1993 PF09351.5 EIW85018.1 - 0.083 12.8 0.4 0.083 12.8 0.3 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1993) VitD-bind_III PF09164.5 EIW85018.1 - 0.12 11.9 0.0 0.4 10.3 0.0 1.8 1 0 0 1 1 1 0 Vitamin D binding protein, domain III DUF1664 PF07889.7 EIW85018.1 - 0.13 12.0 5.4 1.7 8.4 0.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4179 PF13786.1 EIW85018.1 - 0.25 11.5 1.2 1.9 8.7 0.0 2.6 2 1 0 3 3 3 0 Domain of unknown function (DUF4179) NAP PF00956.13 EIW85018.1 - 0.25 10.4 5.2 0.51 9.4 3.6 1.6 1 1 0 1 1 1 0 Nucleosome assembly protein (NAP) LOH1CR12 PF10158.4 EIW85018.1 - 0.26 11.0 2.6 7.4 6.3 0.1 2.6 2 1 0 2 2 2 0 Tumour suppressor protein DASH_Dam1 PF08653.5 EIW85018.1 - 0.31 10.8 3.3 0.48 10.2 0.1 2.6 2 1 1 3 3 3 0 DASH complex subunit Dam1 Allexi_40kDa PF05549.6 EIW85018.1 - 0.61 9.3 4.2 0.97 8.6 0.2 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein BLOC1_2 PF10046.4 EIW85018.1 - 1.3 9.2 6.8 1.4 9.1 0.3 3.1 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FUSC PF04632.7 EIW85018.1 - 1.8 6.9 9.3 0.094 11.1 1.0 2.0 1 1 1 2 2 2 0 Fusaric acid resistance protein family Tropomyosin_1 PF12718.2 EIW85018.1 - 2.2 8.1 9.4 4 7.2 1.4 2.4 2 1 0 2 2 2 0 Tropomyosin like TBPIP PF07106.8 EIW85018.1 - 3.1 7.3 10.4 1.8 8.0 0.3 2.7 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 EIW85018.1 - 4.4 6.9 10.6 63 3.1 5.5 2.8 2 1 0 2 2 2 0 Mnd1 family DUF2077 PF09850.4 EIW85018.1 - 6.5 6.1 8.4 2.1 7.7 0.0 3.3 1 1 2 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2077) HET PF06985.6 EIW85019.1 - 2e-07 31.2 0.1 0.00073 19.7 0.0 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Aldo_ket_red PF00248.16 EIW85020.1 - 1.2e-48 165.3 0.0 1.4e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Asn_synthase PF00733.16 EIW85021.1 - 2.9e-71 239.9 0.0 6.5e-71 238.8 0.0 1.5 2 0 0 2 2 2 1 Asparagine synthase GATase_7 PF13537.1 EIW85021.1 - 4.1e-35 120.2 0.0 7.2e-35 119.4 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EIW85021.1 - 2.2e-30 105.3 0.0 9.9e-30 103.2 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EIW85021.1 - 7.9e-05 21.9 0.0 0.00014 21.1 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EIW85021.1 - 0.0017 17.1 0.0 0.21 10.2 0.0 2.5 1 1 2 3 3 3 2 Glutamine amidotransferases class-II QueC PF06508.8 EIW85021.1 - 0.0072 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.12 EIW85021.1 - 0.027 13.3 0.0 0.047 12.5 0.0 1.3 1 0 0 1 1 1 0 NAD synthase tRNA_Me_trans PF03054.11 EIW85021.1 - 0.12 10.8 0.0 0.21 10.0 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase RhoGEF PF00621.15 EIW85022.1 - 3.1e-21 76.0 0.2 1.6e-15 57.4 0.0 2.2 2 0 0 2 2 2 2 RhoGEF domain Methyltransf_16 PF10294.4 EIW85023.1 - 2.8e-17 62.7 0.0 1.9e-12 47.0 0.0 2.1 1 1 1 2 2 2 2 Putative methyltransferase Methyltransf_18 PF12847.2 EIW85023.1 - 1.8e-05 25.3 0.0 2.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW85023.1 - 0.00071 19.3 0.0 0.0011 18.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW85023.1 - 0.036 14.0 1.1 0.062 13.3 0.8 1.4 1 1 0 1 1 1 0 Methyltransferase domain EF-hand_8 PF13833.1 EIW85024.1 - 0.0051 16.3 0.3 0.05 13.2 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF_assoc_2 PF08356.7 EIW85024.1 - 0.011 15.4 0.1 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 EF hand associated Phage_Gp15 PF06854.6 EIW85024.1 - 0.026 14.0 0.0 0.034 13.6 0.0 1.1 1 0 0 1 1 1 0 Bacteriophage Gp15 protein EF_assoc_1 PF08355.7 EIW85024.1 - 0.043 13.0 0.0 0.064 12.5 0.0 1.3 1 0 0 1 1 1 0 EF hand associated Gluconate_2-dh3 PF13618.1 EIW85024.1 - 0.07 13.2 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 DEAD PF00270.24 EIW85025.1 - 6.4e-41 139.6 0.0 5.5e-40 136.6 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW85025.1 - 2.2e-23 81.8 0.1 5.5e-23 80.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EIW85025.1 - 6.3e-05 21.9 0.0 9.2e-05 21.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EIW85025.1 - 0.012 15.4 0.6 0.031 14.1 0.0 1.9 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Pkinase PF00069.20 EIW85027.1 - 3.7e-48 163.9 0.0 1.4e-45 155.5 0.0 3.4 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW85027.1 - 3.5e-19 68.8 0.0 1.5e-16 60.3 0.0 2.9 3 0 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EIW85027.1 - 0.012 15.3 0.1 0.03 14.0 0.1 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family PRKCSH PF07915.8 EIW85028.1 - 2.5e-12 47.4 0.0 6.6e-12 46.0 0.0 1.8 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EIW85028.1 - 0.00038 19.9 0.1 0.00086 18.8 0.0 1.5 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PsbU PF06514.6 EIW85028.1 - 0.023 14.5 0.0 3.7 7.4 0.0 2.4 2 0 0 2 2 2 0 Photosystem II 12 kDa extrinsic protein (PsbU) FAD_binding_3 PF01494.14 EIW85029.1 - 4.3e-21 75.3 0.0 6.1e-21 74.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIW85029.1 - 5.8e-05 22.1 0.1 0.00027 19.9 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EIW85029.1 - 9.7e-05 22.3 0.0 0.00032 20.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW85029.1 - 0.0001 22.2 0.1 0.00023 21.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EIW85029.1 - 0.00012 21.1 0.0 0.00015 20.7 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EIW85029.1 - 0.00058 20.2 0.1 0.0029 17.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.5 EIW85029.1 - 0.00098 18.0 0.0 0.032 13.0 0.0 2.2 2 0 0 2 2 2 1 Squalene epoxidase FAD_oxidored PF12831.2 EIW85029.1 - 0.0011 18.1 0.7 0.004 16.2 0.5 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EIW85029.1 - 0.013 13.9 0.0 0.02 13.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 EIW85029.1 - 0.021 14.4 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 EIW85029.1 - 0.029 13.0 0.5 1.7 7.1 0.1 2.5 3 0 0 3 3 3 0 Tryptophan halogenase ThiF PF00899.16 EIW85029.1 - 0.036 13.8 0.3 0.077 12.8 0.2 1.5 1 0 0 1 1 1 0 ThiF family Thi4 PF01946.12 EIW85029.1 - 0.12 11.4 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 EIW85029.1 - 0.17 10.6 0.3 0.39 9.5 0.1 1.6 2 0 0 2 2 2 0 FAD binding domain Aminotran_5 PF00266.14 EIW85030.1 - 9.3e-15 54.2 0.0 2.2e-14 52.9 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EIW85030.1 - 0.14 11.1 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Hexapep PF00132.19 EIW85031.1 - 2.7e-12 45.5 15.1 2.6e-05 23.5 0.6 4.2 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EIW85031.1 - 2e-08 33.8 0.0 3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase W2 PF02020.13 EIW85031.1 - 4.3e-08 32.9 2.4 1.5e-07 31.2 1.7 2.0 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon NTP_transf_3 PF12804.2 EIW85031.1 - 0.00027 21.0 0.0 0.00047 20.2 0.0 1.4 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EIW85031.1 - 0.0014 18.1 14.8 0.34 10.4 4.1 3.6 2 2 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EIW85031.1 - 0.061 11.8 0.2 0.12 10.9 0.2 1.4 1 0 0 1 1 1 0 L-fucokinase Nol1_Nop2_Fmu PF01189.12 EIW85033.1 - 2.1e-101 339.0 0.0 2.9e-101 338.5 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 EIW85033.1 - 0.0017 17.9 0.0 0.0026 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIW85033.1 - 0.0022 17.5 0.0 0.0038 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.14 EIW85033.1 - 0.005 16.8 0.1 0.0097 15.9 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase Met_10 PF02475.11 EIW85033.1 - 0.005 16.4 0.0 0.0099 15.4 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein DUF938 PF06080.7 EIW85033.1 - 0.016 14.7 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FUN14 PF04930.10 EIW85034.1 - 2.7e-18 66.0 0.2 4e-18 65.5 0.1 1.3 1 0 0 1 1 1 1 FUN14 family Ion_trans PF00520.26 EIW85036.1 - 0.00032 20.0 1.4 0.00047 19.4 1.0 1.2 1 0 0 1 1 1 1 Ion transport protein DUF1516 PF07457.6 EIW85036.1 - 0.037 14.1 0.0 0.53 10.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1516) DASH_Dad4 PF08650.5 EIW85037.1 - 5.7e-16 58.1 1.8 6.3e-16 58.0 1.3 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 HEAT PF02985.17 EIW85038.1 - 3e-17 61.0 11.5 0.1 12.7 0.0 9.0 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.1 EIW85038.1 - 1.3e-13 50.9 9.2 9e-05 22.6 0.0 6.5 3 2 2 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 EIW85038.1 - 0.00015 22.1 15.7 0.98 9.9 0.1 7.8 7 1 1 8 8 8 2 HEAT-like repeat Cohesin_HEAT PF12765.2 EIW85038.1 - 0.077 12.9 0.2 26 4.9 0.0 3.1 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Aminotran_1_2 PF00155.16 EIW85039.1 - 3.5e-87 292.6 0.0 4e-87 292.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Exo_endo_phos PF03372.18 EIW85039.1 - 0.08 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family zf-AN1 PF01428.11 EIW85040.1 - 1.3e-08 34.5 10.6 2.1e-08 33.9 7.4 1.4 1 1 0 1 1 1 1 AN1-like Zinc finger IBR PF01485.16 EIW85040.1 - 0.48 10.3 10.6 0.63 9.9 7.1 1.6 1 1 0 1 1 1 0 IBR domain Lyase_1 PF00206.15 EIW85041.1 - 3.1e-98 328.8 0.0 4.6e-98 328.2 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EIW85041.1 - 1.3e-28 98.8 0.6 2.7e-28 97.8 0.2 1.8 2 0 0 2 2 2 1 Argininosuccinate lyase C-terminal SNARE PF05739.14 EIW85042.1 - 6.3e-15 54.6 5.0 6.3e-15 54.6 3.5 2.3 2 1 1 3 3 3 1 SNARE domain Syntaxin PF00804.20 EIW85042.1 - 1.3e-14 54.1 9.7 3.9e-13 49.4 1.3 2.4 2 0 0 2 2 2 2 Syntaxin BLOC1_2 PF10046.4 EIW85042.1 - 0.00029 20.9 8.7 0.26 11.4 2.3 3.4 2 2 1 3 3 3 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 Syntaxin_2 PF14523.1 EIW85042.1 - 0.0014 18.5 13.6 0.0046 16.9 4.7 2.3 2 0 0 2 2 2 1 Syntaxin-like protein EMP24_GP25L PF01105.19 EIW85042.1 - 0.0024 17.6 1.9 0.0024 17.6 1.3 2.7 2 1 0 2 2 2 1 emp24/gp25L/p24 family/GOLD Tweety PF04906.8 EIW85042.1 - 0.0057 15.1 0.6 0.0057 15.1 0.4 1.7 2 0 0 2 2 2 1 Tweety Spectrin PF00435.16 EIW85042.1 - 0.023 14.9 6.9 1.3 9.3 0.0 2.9 3 1 0 3 3 2 0 Spectrin repeat DUF4094 PF13334.1 EIW85042.1 - 0.027 14.8 3.4 0.19 12.1 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) MCPsignal PF00015.16 EIW85042.1 - 0.036 13.6 10.0 0.052 13.0 3.0 2.3 2 1 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain VitD-bind_III PF09164.5 EIW85042.1 - 0.043 13.4 0.0 0.14 11.8 0.0 1.8 1 0 0 1 1 1 0 Vitamin D binding protein, domain III NTF2 PF02136.15 EIW85042.1 - 0.064 13.6 0.3 0.6 10.4 0.0 2.2 2 0 0 2 2 2 0 Nuclear transport factor 2 (NTF2) domain DUF4407 PF14362.1 EIW85042.1 - 0.072 12.0 8.0 0.48 9.3 5.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF805 PF05656.9 EIW85042.1 - 0.11 12.2 0.2 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DUF3753 PF12575.3 EIW85042.1 - 0.13 12.1 4.8 0.13 12.1 1.9 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF3753) NPV_P10 PF05531.7 EIW85042.1 - 0.14 12.4 4.2 7 6.9 1.4 2.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Rifin_STEVOR PF02009.11 EIW85042.1 - 0.15 11.7 12.0 0.42 10.2 8.3 1.8 1 1 0 1 1 1 0 Rifin/stevor family E2R135 PF11570.3 EIW85042.1 - 0.2 11.7 5.9 1.2 9.2 0.1 2.7 2 0 0 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 VIT1 PF01988.14 EIW85042.1 - 0.24 10.8 4.7 18 4.7 3.3 2.5 1 1 0 1 1 1 0 VIT family ABC2_membrane_3 PF12698.2 EIW85042.1 - 0.43 9.5 2.9 0.53 9.2 2.0 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein Spc7 PF08317.6 EIW85042.1 - 0.95 8.0 13.9 0.13 10.8 1.8 2.5 1 1 2 3 3 3 0 Spc7 kinetochore protein Laminin_II PF06009.7 EIW85042.1 - 1.1 8.9 7.4 2.6 7.7 1.7 2.5 2 0 0 2 2 2 0 Laminin Domain II Tropomyosin_1 PF12718.2 EIW85042.1 - 2 8.2 11.6 0.71 9.7 0.8 2.8 2 1 0 2 2 2 0 Tropomyosin like DUF745 PF05335.8 EIW85042.1 - 2.3 7.7 9.8 0.33 10.4 1.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF745) FUSC PF04632.7 EIW85042.1 - 3.1 6.1 7.3 0.34 9.2 0.6 2.2 1 1 1 3 3 3 0 Fusaric acid resistance protein family AAA_13 PF13166.1 EIW85042.1 - 3.8 5.8 14.1 2.2 6.6 0.6 2.2 1 1 1 2 2 2 0 AAA domain MFS_1 PF07690.11 EIW85043.1 - 9.8e-17 60.6 33.2 3.7e-16 58.8 20.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 EIW85043.1 - 1e-10 41.3 4.0 1e-10 41.3 2.8 2.5 3 0 0 3 3 3 1 Nodulin-like Ist1 PF03398.9 EIW85044.1 - 1.3e-30 106.0 0.0 2.1e-30 105.3 0.0 1.4 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway RabGAP-TBC PF00566.13 EIW85044.1 - 1e-14 54.5 0.4 3.4e-12 46.2 0.0 2.3 2 0 0 2 2 2 2 Rab-GTPase-TBC domain 2OG-FeII_Oxy_3 PF13640.1 EIW85045.1 - 2.6e-06 27.8 0.0 4.2e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EIW85045.1 - 4.3e-06 26.2 0.1 8.8e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIW85045.1 - 0.016 15.4 0.0 0.024 14.9 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DEAD PF00270.24 EIW85046.1 - 2.5e-47 160.4 0.0 4.8e-47 159.5 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW85046.1 - 1.3e-21 76.2 0.0 2.6e-11 43.2 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EIW85046.1 - 9.7e-05 22.2 0.0 0.00037 20.3 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIW85046.1 - 0.044 13.9 0.0 0.14 12.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain TRAPPC10 PF12584.3 EIW85047.1 - 9.7e-18 64.0 0.0 2e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 ALG3 PF05208.8 EIW85048.1 - 3.7e-120 401.5 13.9 4.5e-120 401.2 9.6 1.0 1 0 0 1 1 1 1 ALG3 protein PPP4R2 PF09184.6 EIW85049.1 - 5e-20 72.2 0.5 1.4e-19 70.7 0.0 1.8 2 0 0 2 2 2 1 PPP4R2 SUI1 PF01253.17 EIW85050.1 - 7.2e-31 105.8 0.5 8.7e-31 105.5 0.3 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF608 PF04685.8 EIW85050.1 - 0.031 12.9 0.0 0.032 12.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF608 DUF1777 PF08648.7 EIW85051.1 - 7.1e-26 91.0 35.8 7.1e-26 91.0 24.8 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) RRM_1 PF00076.17 EIW85052.1 - 2.6e-12 46.2 0.0 7.3e-12 44.7 0.0 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW85052.1 - 5.1e-09 35.9 0.0 7.7e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW85052.1 - 6.3e-05 22.7 0.0 0.00018 21.3 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA PF00004.24 EIW85053.1 - 6.1e-44 149.4 0.0 2.1e-43 147.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIW85053.1 - 2.6e-08 33.6 0.1 8.4e-08 32.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIW85053.1 - 7.3e-07 29.3 0.0 2.6e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.9 EIW85053.1 - 9e-07 28.9 0.0 2.2e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EIW85053.1 - 2.3e-06 26.7 0.0 4.3e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.1 EIW85053.1 - 2.3e-05 24.5 1.7 0.0012 18.9 0.2 3.1 3 1 0 3 3 2 1 AAA domain AAA_28 PF13521.1 EIW85053.1 - 6.9e-05 22.8 0.1 0.00034 20.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIW85053.1 - 0.00015 21.4 0.1 0.00042 20.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EIW85053.1 - 0.00058 19.7 0.0 0.0038 17.1 0.0 2.2 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.10 EIW85053.1 - 0.00067 19.4 0.1 0.0055 16.4 0.0 2.3 2 1 0 2 2 2 1 NTPase AAA_17 PF13207.1 EIW85053.1 - 0.001 19.8 0.0 0.0068 17.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EIW85053.1 - 0.0017 18.6 0.0 0.011 15.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIW85053.1 - 0.0018 18.4 0.0 0.0042 17.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase UPF0079 PF02367.12 EIW85053.1 - 0.0028 17.2 0.1 0.023 14.2 0.0 2.2 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_25 PF13481.1 EIW85053.1 - 0.0032 16.9 1.5 0.012 14.9 0.0 2.3 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.7 EIW85053.1 - 0.0034 16.4 0.0 0.0067 15.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EIW85053.1 - 0.0042 16.5 0.6 0.01 15.2 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein CENP-F_leu_zip PF10473.4 EIW85053.1 - 0.0042 16.9 2.0 0.0074 16.1 1.4 1.4 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 AAA_11 PF13086.1 EIW85053.1 - 0.0046 16.5 0.0 0.018 14.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EIW85053.1 - 0.0048 16.7 0.0 0.016 15.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EIW85053.1 - 0.0062 16.2 0.1 0.053 13.1 0.0 2.2 2 0 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.16 EIW85053.1 - 0.0069 15.5 0.1 0.016 14.4 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EIW85053.1 - 0.0073 15.9 0.0 0.018 14.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EIW85053.1 - 0.011 14.4 0.0 0.019 13.7 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus AAA_30 PF13604.1 EIW85053.1 - 0.012 15.2 0.0 0.023 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EIW85053.1 - 0.015 14.8 0.1 0.035 13.6 0.1 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIW85053.1 - 0.015 14.3 0.0 0.034 13.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Arch_ATPase PF01637.13 EIW85053.1 - 0.016 14.9 2.0 0.15 11.7 0.0 2.9 2 1 1 3 3 3 0 Archaeal ATPase AFG1_ATPase PF03969.11 EIW85053.1 - 0.024 13.4 0.0 0.081 11.7 0.0 1.8 2 0 0 2 2 2 0 AFG1-like ATPase Sigma54_activat PF00158.21 EIW85053.1 - 0.065 12.7 0.3 1.1 8.6 0.0 2.7 3 1 0 3 3 3 0 Sigma-54 interaction domain KaiC PF06745.8 EIW85053.1 - 0.079 12.0 0.2 0.36 9.8 0.0 2.0 2 0 0 2 2 2 0 KaiC AAA_10 PF12846.2 EIW85053.1 - 0.097 12.0 0.5 1.2 8.5 0.0 2.6 1 1 0 3 3 3 0 AAA-like domain Parvo_NS1 PF01057.12 EIW85053.1 - 0.12 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.1 EIW85053.1 - 0.14 12.4 4.4 0.81 9.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain P5CR_dimer PF14748.1 EIW85054.1 - 7.4e-21 74.1 2.8 2.3e-16 59.7 0.1 2.8 2 1 1 3 3 3 2 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EIW85054.1 - 8.4e-10 38.9 0.0 2e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Glyco_tran_28_C PF04101.11 EIW85055.1 - 8.6e-28 97.0 0.0 9.2e-28 96.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EIW85055.1 - 2.2e-09 36.9 0.0 2.8e-09 36.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 1 Glyco_trans_1_4 PF13692.1 EIW85055.1 - 0.0095 16.0 0.0 0.013 15.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Methyltransf_11 PF08241.7 EIW85056.1 - 2.3e-06 27.9 0.0 4.3e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW85056.1 - 0.0044 16.6 0.0 0.01 15.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW85056.1 - 0.0057 17.2 0.0 0.011 16.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW85056.1 - 0.13 12.7 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NAC PF01849.13 EIW85057.1 - 1.7e-19 69.0 0.0 3.4e-19 68.1 0.0 1.5 1 0 0 1 1 1 1 NAC domain UBA PF00627.26 EIW85057.1 - 0.00063 19.5 0.6 0.0015 18.2 0.0 2.0 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.1 EIW85057.1 - 0.089 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain HSP90 PF00183.13 EIW85058.1 - 4.9e-252 837.0 30.0 5.9e-252 836.7 20.8 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EIW85058.1 - 5e-11 42.4 0.1 5e-11 42.4 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EIW85058.1 - 6.4e-11 41.9 0.0 1.2e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_C37 PF05416.7 EIW85058.1 - 0.11 10.7 6.1 2.6 6.2 0.1 2.2 2 0 0 2 2 2 0 Southampton virus-type processing peptidase DUF1510 PF07423.6 EIW85058.1 - 0.48 9.7 17.2 0.035 13.4 7.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Aminotran_5 PF00266.14 EIW85059.1 - 1.9e-19 69.6 0.0 5.5e-19 68.1 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_5 PF00266.14 EIW85060.1 - 7.2e-07 28.2 0.0 8.2e-07 28.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Ribosomal_S21e PF01249.13 EIW85061.1 - 3.2e-38 129.5 0.1 3.6e-38 129.3 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e RabGAP-TBC PF00566.13 EIW85062.1 - 3.3e-41 141.1 6.1 3.1e-39 134.6 4.2 2.3 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 EIW85062.1 - 1.3e-06 27.9 0.1 0.022 14.0 0.0 3.3 2 1 0 2 2 2 2 Domain of unknown function (DUF3548) DcpS_C PF11969.3 EIW85063.1 - 9e-16 58.1 0.1 1.5e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EIW85063.1 - 4.4e-12 46.3 0.0 1e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 HIT domain ox_reductase_C PF08635.5 EIW85064.1 - 1.8e-71 238.1 0.1 2.9e-71 237.4 0.1 1.3 1 0 0 1 1 1 1 Putative oxidoreductase C terminal GFO_IDH_MocA PF01408.17 EIW85064.1 - 1e-21 77.6 0.0 2.5e-21 76.3 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EIW85064.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Cep57_CLD_2 PF14197.1 EIW85065.1 - 0.015 15.2 3.7 0.023 14.6 2.6 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 HALZ PF02183.13 EIW85065.1 - 0.028 14.1 1.9 0.058 13.1 1.3 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF972 PF06156.8 EIW85065.1 - 0.071 13.4 3.2 0.091 13.1 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF904 PF06005.7 EIW85065.1 - 0.075 13.3 4.5 0.08 13.2 2.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) CENP-Q PF13094.1 EIW85065.1 - 0.075 13.0 8.8 0.052 13.5 5.2 1.4 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 EIW85065.1 - 0.1 12.1 4.1 0.11 12.0 2.9 1.1 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EIW85065.1 - 0.19 11.2 3.2 0.29 10.6 2.2 1.3 1 0 0 1 1 1 0 Septum formation initiator OmpH PF03938.9 EIW85065.1 - 0.22 11.4 6.4 0.28 11.1 4.4 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) APG6 PF04111.7 EIW85065.1 - 0.23 10.4 4.7 0.27 10.2 3.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 PA26 PF04636.8 EIW85065.1 - 0.3 9.7 2.4 0.31 9.6 1.7 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF2681 PF10883.3 EIW85065.1 - 0.48 10.6 6.6 0.74 10.0 4.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) bZIP_Maf PF03131.12 EIW85065.1 - 0.76 10.1 7.1 1.1 9.6 4.9 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor Spc24 PF08286.6 EIW85065.1 - 1.3 8.7 4.8 1.8 8.3 3.3 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Bap31 PF05529.7 EIW85065.1 - 1.4 8.3 4.7 1.8 7.9 3.3 1.1 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Rotamase PF00639.16 EIW85065.1 - 9.9 6.9 6.8 21 5.9 4.7 1.7 1 1 0 1 1 1 0 PPIC-type PPIASE domain PIG-Y PF15159.1 EIW85066.1 - 8.3e-08 32.3 2.2 9.7e-08 32.1 1.5 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Sfi1 PF08457.5 EIW85067.1 - 1.8e-22 79.4 110.7 9.1e-11 40.8 42.5 4.9 1 1 2 4 4 4 4 Sfi1 spindle body protein Utp21 PF04192.7 EIW85068.1 - 1.7e-56 191.0 0.1 2.4e-56 190.5 0.1 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EIW85068.1 - 3.1e-19 68.0 19.8 6.7e-08 32.1 0.1 8.1 9 0 0 9 9 9 5 WD domain, G-beta repeat Nup160 PF11715.3 EIW85068.1 - 0.005 15.0 0.6 0.23 9.5 0.1 2.5 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EIW85068.1 - 0.01 14.1 0.0 0.15 10.2 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 EIW85068.1 - 0.06 12.0 6.4 0.25 10.0 0.0 3.9 2 2 3 5 5 5 0 Nup133 N terminal like Hira PF07569.6 EIW85068.1 - 0.095 11.8 0.0 1.3 8.1 0.0 2.6 2 0 0 2 2 2 0 TUP1-like enhancer of split MFS_1 PF07690.11 EIW85069.1 - 3.7e-53 180.4 41.1 3.7e-53 180.4 28.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EIW85069.1 - 2.3e-16 59.1 13.3 3.5e-16 58.5 9.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EIW85069.1 - 1.5e-12 46.8 15.9 1.5e-12 46.8 11.0 3.2 2 1 1 3 3 3 1 Sugar (and other) transporter IncA PF04156.9 EIW85069.1 - 0.019 14.5 2.0 0.06 12.9 1.4 1.8 1 0 0 1 1 1 0 IncA protein DUF3040 PF11239.3 EIW85069.1 - 0.055 13.5 3.4 0.25 11.4 1.4 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) Neurensin PF14927.1 EIW85069.1 - 3.8 6.8 8.0 23 4.3 5.0 2.7 2 1 0 2 2 2 0 Neurensin DUF4231 PF14015.1 EIW85069.1 - 4.2 7.4 10.8 0.47 10.4 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) Ras PF00071.17 EIW85070.1 - 3.2e-50 169.6 0.0 4e-50 169.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW85070.1 - 2.7e-16 60.1 0.0 4.3e-16 59.4 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW85070.1 - 3.5e-10 39.3 0.0 4.8e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW85070.1 - 0.00032 19.9 0.0 0.0004 19.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EIW85070.1 - 0.00044 19.0 0.9 0.24 10.0 0.0 2.8 2 1 1 3 3 3 2 G-protein alpha subunit RNA_helicase PF00910.17 EIW85070.1 - 0.014 15.5 0.1 0.12 12.5 0.1 2.1 1 1 0 1 1 1 0 RNA helicase Pox_A32 PF04665.7 EIW85070.1 - 0.028 13.6 0.1 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_22 PF13401.1 EIW85070.1 - 0.032 14.3 0.1 0.12 12.4 0.0 1.9 1 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EIW85070.1 - 0.075 12.8 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain STAS PF01740.16 EIW85070.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.6 1 1 0 1 1 1 0 STAS domain UPF0079 PF02367.12 EIW85070.1 - 0.15 11.7 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Pkinase PF00069.20 EIW85071.1 - 1.4e-33 116.1 0.0 1.6e-33 115.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW85071.1 - 1.5e-11 43.8 0.0 1.9e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW85071.1 - 0.00039 20.2 0.0 0.61 9.7 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family Pyr_redox_3 PF13738.1 EIW85072.1 - 6.4e-16 59.0 0.0 1e-15 58.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW85072.1 - 1.5e-08 33.9 0.0 6.6e-08 31.8 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EIW85072.1 - 1.1e-06 28.5 0.0 3.8e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FMO-like PF00743.14 EIW85072.1 - 2.8e-06 25.8 0.1 1e-05 23.9 0.1 1.8 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like DAO PF01266.19 EIW85072.1 - 0.055 12.3 0.0 0.12 11.1 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EIW85072.1 - 0.057 13.1 0.0 0.15 11.7 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EIW85072.1 - 0.08 12.8 0.0 0.12 12.1 0.0 1.4 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Cas_APE2256 PF09651.5 EIW85072.1 - 0.14 11.8 0.0 17 5.1 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_APE2256) Vac_ImportDeg PF09783.4 EIW85073.1 - 2.2e-56 190.1 0.2 2.8e-51 173.5 0.0 2.1 2 0 0 2 2 2 2 Vacuolar import and degradation protein Gly_transf_sug PF04488.10 EIW85074.1 - 7.4e-05 23.0 0.0 0.00019 21.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EIW85074.1 - 0.21 10.7 0.2 0.37 9.8 0.1 1.3 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein JmjC PF02373.17 EIW85075.1 - 2.3e-14 53.6 0.1 7.2e-14 51.9 0.0 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase GPI PF06560.6 EIW85075.1 - 0.066 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) zf-RING_5 PF14634.1 EIW85076.1 - 6.5e-08 32.1 9.7 1.1e-07 31.4 6.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIW85076.1 - 0.032 14.2 10.7 0.058 13.4 7.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW85076.1 - 0.038 13.6 8.5 0.074 12.7 5.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CALCOCO1 PF07888.6 EIW85076.1 - 0.05 11.8 0.2 0.067 11.4 0.1 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like zf-RING_UBOX PF13445.1 EIW85076.1 - 0.16 11.7 5.3 0.36 10.5 3.7 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.1 EIW85076.1 - 0.62 9.9 10.0 1.3 8.9 6.9 1.6 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.1 EIW85076.1 - 6.3 6.4 10.1 13 5.3 2.2 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 LEA_2 PF03168.8 EIW85077.1 - 5.6e-08 33.0 0.1 9.7e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Late embryogenesis abundant protein DUF1356 PF07092.7 EIW85077.1 - 0.023 13.8 3.0 0.043 13.0 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) RCR PF12273.3 EIW85077.1 - 0.44 11.1 14.6 2 8.9 0.2 2.3 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF726 PF05277.7 EIW85078.1 - 3.9e-85 285.7 0.5 5.7e-85 285.2 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) RRM_1 PF00076.17 EIW85079.1 - 0.00073 19.1 0.0 0.0019 17.8 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 EIW85079.1 - 0.0014 18.2 2.6 0.004 16.8 1.8 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Limkain-b1 PF11608.3 EIW85079.1 - 0.014 15.0 0.0 0.039 13.7 0.0 1.7 2 0 0 2 2 2 0 Limkain b1 zf-CCCH_2 PF14608.1 EIW85079.1 - 0.029 14.3 1.3 0.079 12.9 0.9 1.8 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type RRM_5 PF13893.1 EIW85079.1 - 0.066 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cript PF10235.4 EIW85079.1 - 1.5 9.2 7.4 4.8 7.6 0.7 2.6 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT Zn_ribbon_recom PF13408.1 EIW85079.1 - 2.5 8.4 8.3 0.17 12.1 1.1 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain ThiF PF00899.16 EIW85080.1 - 6.5e-38 129.6 0.1 1.8e-37 128.1 0.0 1.7 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 EIW85080.1 - 2e-24 85.1 0.7 3.4e-24 84.4 0.5 1.4 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 EIW85080.1 - 1.8e-23 81.8 0.2 3.8e-23 80.8 0.1 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EIW85080.1 - 6.2e-18 63.9 2.5 1.4e-17 62.7 1.8 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EIW85080.1 - 0.0017 18.4 0.0 0.0036 17.3 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MoeZ_MoeB PF05237.8 EIW85080.1 - 0.0037 16.8 0.8 0.02 14.4 0.0 2.2 2 0 0 2 2 2 1 MoeZ/MoeB domain UBA_e1_C PF09358.5 EIW85080.1 - 0.0067 16.5 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-activating enzyme e1 C-terminal domain Pyr_redox PF00070.22 EIW85080.1 - 0.059 13.7 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EIW85080.1 - 0.13 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RTC PF01137.16 EIW85081.1 - 1.3e-66 223.7 0.0 1.4e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EIW85081.1 - 2.9e-33 113.9 0.0 4.7e-33 113.2 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain OGG_N PF07934.7 EIW85082.1 - 1.9e-28 98.8 0.1 3.8e-28 97.8 0.0 1.5 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EIW85082.1 - 1.7e-12 47.6 0.0 2.6e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EIW85082.1 - 0.0025 17.3 0.0 0.0081 15.8 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF559 PF04480.7 EIW85082.1 - 0.085 12.5 0.0 16 5.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF559) DUF3432 PF11914.3 EIW85082.1 - 1.2 9.2 12.6 0.55 10.2 3.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3432) NMT PF01233.14 EIW85083.1 - 8.8e-76 253.0 0.0 1.5e-75 252.2 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EIW85083.1 - 2.2e-72 242.4 0.0 9.7e-72 240.3 0.0 1.9 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EIW85083.1 - 5.7e-06 26.2 0.0 4e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF3464 PF11947.3 EIW85083.1 - 0.13 11.7 0.9 0.26 10.7 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) BRF1 PF07741.8 EIW85083.1 - 0.14 12.3 4.3 0.31 11.2 3.0 1.5 1 0 0 1 1 1 0 Brf1-like TBP-binding domain NST1 PF13945.1 EIW85083.1 - 0.22 11.5 5.4 0.33 11.0 3.7 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Mak16 PF04874.9 EIW85083.1 - 0.23 11.5 1.6 0.53 10.3 1.1 1.6 1 0 0 1 1 1 0 Mak16 protein C-terminal region UFD1 PF03152.9 EIW85084.1 - 1.2e-64 216.6 0.0 1.6e-64 216.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 EIW85084.1 - 0.00055 19.5 0.1 0.0023 17.5 0.0 2.1 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 Cpn60_TCP1 PF00118.19 EIW85085.1 - 7.2e-142 473.4 10.1 8.2e-142 473.2 7.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF3599 PF12206.3 EIW85085.1 - 0.057 13.6 0.1 0.14 12.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3599) ATP-synt_D PF01813.12 EIW85086.1 - 1.2e-64 217.4 4.1 1.5e-64 217.2 2.9 1.1 1 0 0 1 1 1 1 ATP synthase subunit D KOW PF00467.24 EIW85087.1 - 9.7e-10 37.7 3.5 9.7e-10 37.7 2.4 2.3 3 0 0 3 3 3 1 KOW motif FRG1 PF06229.7 EIW85088.1 - 9.5e-30 103.4 0.0 1.6e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 EIW85088.1 - 0.00029 20.8 0.0 0.00048 20.1 0.0 1.4 1 0 0 1 1 1 1 Fascin domain DUF1754 PF08555.5 EIW85088.1 - 0.015 15.8 8.6 1 9.9 1.5 2.3 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) BRF1 PF07741.8 EIW85088.1 - 1 9.6 7.0 0.2 11.9 0.4 2.3 2 0 0 2 2 2 0 Brf1-like TBP-binding domain SRPRB PF09439.5 EIW85089.1 - 1.6e-24 86.0 0.0 2.1e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EIW85089.1 - 1.7e-14 53.4 0.0 2.3e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW85089.1 - 7.3e-08 31.8 0.0 9.4e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EIW85089.1 - 8.9e-08 32.0 0.0 1.5e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIW85089.1 - 0.00065 19.0 0.0 0.0014 17.9 0.0 1.6 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EIW85089.1 - 0.0016 17.8 0.1 0.18 11.2 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_25 PF13481.1 EIW85089.1 - 0.017 14.5 0.1 0.047 13.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EIW85089.1 - 0.029 14.8 0.0 0.051 14.0 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein Arf PF00025.16 EIW85090.1 - 2e-64 216.0 0.0 2.3e-64 215.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EIW85090.1 - 1.3e-11 44.0 0.0 1.7e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EIW85090.1 - 1.3e-10 40.5 0.2 2.5e-07 29.7 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EIW85090.1 - 9e-08 32.6 0.0 1.2e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EIW85090.1 - 2.4e-07 30.6 0.0 8.4e-07 28.9 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.17 EIW85090.1 - 1.1e-06 28.1 0.0 1.3e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EIW85090.1 - 2.5e-05 23.5 0.0 2.7e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIW85090.1 - 0.0037 16.7 0.0 0.14 11.6 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EIW85090.1 - 0.015 14.7 0.0 0.048 13.1 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Mannosyl_trans PF05007.8 EIW85091.1 - 4.9e-72 242.6 14.1 6.2e-72 242.3 9.8 1.1 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EIW85091.1 - 8.5e-14 51.2 12.3 2.4e-13 49.7 8.5 1.7 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U OPT PF03169.10 EIW85092.1 - 3.5e-164 547.6 44.0 4e-164 547.4 30.5 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Exo_endo_phos PF03372.18 EIW85093.1 - 5.7e-16 59.1 0.1 9.7e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Alpha_E3_glycop PF01563.11 EIW85093.1 - 0.088 12.6 0.1 0.2 11.4 0.0 1.5 1 0 0 1 1 1 0 Alphavirus E3 glycoprotein MFS_1 PF07690.11 EIW85094.1 - 2.4e-24 85.7 37.9 2.4e-18 66.0 15.8 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Ribosomal_L3 PF00297.17 EIW85095.1 - 1.4e-37 129.5 1.2 6e-36 124.1 0.8 2.2 1 1 0 1 1 1 1 Ribosomal protein L3 Synthase_beta PF11421.3 EIW85095.1 - 0.17 12.5 0.3 0.17 12.5 0.2 1.8 2 0 0 2 2 2 0 ATP synthase F1 beta subunit Rrn6 PF10214.4 EIW85096.1 - 1.6e-10 39.7 0.3 0.00077 17.6 0.0 3.1 3 0 0 3 3 3 3 RNA polymerase I-specific transcription-initiation factor Mito_carr PF00153.22 EIW85097.1 - 8e-49 163.3 0.3 7.1e-15 54.4 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein TRAPP PF04051.11 EIW85098.1 - 4.2e-36 123.7 0.0 5.6e-36 123.3 0.0 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component BCS1_N PF08740.6 EIW85099.1 - 1.5e-46 158.4 1.4 2.1e-46 157.9 1.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EIW85099.1 - 5.5e-19 68.6 0.0 9e-19 67.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIW85099.1 - 3.5e-05 24.6 0.0 7.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EIW85099.1 - 0.00013 21.4 0.0 0.00035 20.0 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EIW85099.1 - 0.0015 18.4 0.0 0.0037 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW85099.1 - 0.0048 16.8 0.1 0.015 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EIW85099.1 - 0.0056 16.4 0.0 0.024 14.3 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_18 PF13238.1 EIW85099.1 - 0.011 16.0 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EIW85099.1 - 0.017 15.0 0.0 0.31 11.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EIW85099.1 - 0.021 14.3 0.0 0.26 10.7 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_5 PF07728.9 EIW85099.1 - 0.025 14.2 0.0 0.063 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EIW85099.1 - 0.026 13.4 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.1 EIW85099.1 - 0.031 14.4 0.0 0.082 13.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIW85099.1 - 0.034 13.6 0.0 0.079 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_11 PF13086.1 EIW85099.1 - 0.044 13.3 0.0 0.09 12.3 0.0 1.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EIW85099.1 - 0.068 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin RNA_helicase PF00910.17 EIW85099.1 - 0.077 13.1 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.7 EIW85099.1 - 0.11 12.1 0.1 0.49 10.0 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.1 EIW85099.1 - 0.11 12.7 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DnaJ PF00226.26 EIW85100.1 - 1.5e-17 63.0 0.7 6e-17 61.1 0.2 2.2 2 0 0 2 2 2 1 DnaJ domain Ank_2 PF12796.2 EIW85100.1 - 3.4e-09 36.9 0.0 7.1e-07 29.4 0.0 3.0 1 1 3 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIW85100.1 - 4.2e-07 30.3 0.0 6.3e-06 26.5 0.0 2.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 EIW85100.1 - 2.3e-05 23.9 0.0 0.69 9.8 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EIW85100.1 - 3.7e-05 23.8 0.0 0.006 16.8 0.0 2.7 2 1 1 3 3 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIW85100.1 - 8.2e-05 22.4 0.0 2.6 8.5 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat TATR PF03430.8 EIW85100.1 - 0.052 12.1 9.9 0.071 11.7 6.9 1.1 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF1510 PF07423.6 EIW85100.1 - 0.75 9.1 15.9 1.6 8.0 11.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SAPS PF04499.10 EIW85100.1 - 1.2 7.6 6.3 1.6 7.2 4.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.11 EIW85100.1 - 1.3 8.8 4.7 2.7 7.8 3.3 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 EIW85100.1 - 4.3 4.8 9.5 6.3 4.3 6.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 EIW85100.1 - 4.7 4.8 11.1 6.3 4.3 7.7 1.1 1 0 0 1 1 1 0 Ycf1 LMBR1 PF04791.11 EIW85100.1 - 6.7 5.1 4.3 9.9 4.6 3.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Spore_coat_CotO PF14153.1 EIW85100.1 - 8.9 5.6 17.7 18 4.6 12.3 1.5 1 0 0 1 1 1 0 Spore coat protein CotO Asp-B-Hydro_N PF05279.6 EIW85100.1 - 10 5.9 16.7 18 5.0 11.6 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region LUC7 PF03194.10 EIW85101.1 - 2.2e-71 240.3 2.7 3e-71 239.9 1.9 1.1 1 0 0 1 1 1 1 LUC7 N_terminus Atg14 PF10186.4 EIW85101.1 - 0.0096 14.8 0.7 0.015 14.2 0.5 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Ada3 PF10198.4 EIW85101.1 - 0.011 15.4 0.7 0.022 14.4 0.5 1.5 1 0 0 1 1 1 0 Histone acetyltransferases subunit 3 Mnd1 PF03962.10 EIW85101.1 - 0.06 13.0 1.3 0.12 12.0 0.9 1.5 1 0 0 1 1 1 0 Mnd1 family PRP38_assoc PF12871.2 EIW85101.1 - 3.5 8.2 29.7 0.65 10.5 17.8 1.8 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF4200 PF13863.1 EIW85101.1 - 4.3 7.2 8.4 2.3 8.1 0.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Phage_fiber PF03335.8 EIW85102.1 - 2.1 8.2 6.6 7.6 6.6 0.4 3.2 2 0 0 2 2 2 0 Phage tail fibre repeat UCH PF00443.24 EIW85103.1 - 4.5e-41 140.7 2.1 1.3e-40 139.2 1.5 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW85103.1 - 9.2e-23 81.1 1.6 9.2e-23 81.1 1.1 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EIW85103.1 - 3.4e-06 26.3 0.1 1.1e-05 24.7 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin family DUSP PF06337.7 EIW85103.1 - 0.0026 18.1 2.9 0.0026 18.1 2.0 3.7 3 1 0 3 3 3 1 DUSP domain Gaa1 PF04114.9 EIW85104.1 - 1.9e-66 224.8 8.4 4.7e-36 124.5 0.1 2.4 2 1 0 2 2 2 2 Gaa1-like, GPI transamidase component TAFII55_N PF04658.8 EIW85105.1 - 3.1e-51 173.0 0.0 5.8e-51 172.2 0.0 1.4 1 0 0 1 1 1 1 TAFII55 protein conserved region Macoilin PF09726.4 EIW85105.1 - 0.017 13.4 0.2 0.017 13.4 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF2968 PF11180.3 EIW85105.1 - 0.19 11.0 5.1 0.11 11.8 1.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) 3-alpha PF03475.9 EIW85105.1 - 0.83 9.4 4.5 15 5.4 0.2 3.0 3 0 0 3 3 3 0 3-alpha domain SDA1 PF05285.7 EIW85105.1 - 9.9 5.3 24.0 16 4.6 16.6 1.4 1 0 0 1 1 1 0 SDA1 Tom37 PF10568.4 EIW85106.1 - 7.4e-15 54.9 0.1 1.9e-14 53.6 0.1 1.7 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Tom37_C PF11801.3 EIW85106.1 - 5.5e-13 49.1 0.8 2e-12 47.3 0.1 2.1 2 1 0 2 2 2 1 Tom37 C-terminal domain Exo_endo_phos PF03372.18 EIW85107.1 - 8.1e-22 78.3 0.1 9.9e-22 78.0 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIW85107.1 - 1.5e-05 24.6 0.0 3.4e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Snf7 PF03357.16 EIW85108.1 - 2.2e-15 56.4 2.8 3.2e-15 55.9 1.9 1.2 1 0 0 1 1 1 1 Snf7 SKG6 PF08693.5 EIW85110.1 - 0.0013 18.0 0.9 0.0013 18.0 0.6 1.8 2 0 0 2 2 2 1 Transmembrane alpha-helix domain GRA6 PF05084.8 EIW85110.1 - 0.012 15.1 0.3 0.023 14.2 0.2 1.4 1 0 0 1 1 1 0 Granule antigen protein (GRA6) EphA2_TM PF14575.1 EIW85110.1 - 0.027 14.8 0.0 1.8 9.0 0.0 2.9 2 2 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Ribosomal_L30_N PF08079.7 EIW85111.1 - 4.6e-26 90.6 11.6 8.4e-26 89.7 8.1 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EIW85111.1 - 4.8e-20 70.8 1.6 8.5e-20 70.0 0.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Toprim_C_rpt PF13368.1 EIW85111.1 - 0.46 10.9 3.6 12 6.4 0.7 2.7 2 0 0 2 2 2 0 Topoisomerase C-terminal repeat PQ-loop PF04193.9 EIW85113.1 - 2.4e-38 129.5 9.6 3.9e-21 74.3 0.4 2.4 2 0 0 2 2 2 2 PQ loop repeat CLTH PF10607.4 EIW85113.1 - 2.8e-19 69.2 0.0 5.2e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EIW85113.1 - 7.8e-05 22.3 0.1 0.00018 21.1 0.1 1.6 1 0 0 1 1 1 1 LisH SET PF00856.23 EIW85114.1 - 4.1e-15 56.4 2.9 1.5e-13 51.3 0.3 3.2 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.11 EIW85114.1 - 7e-11 42.3 6.2 7e-11 42.3 4.3 2.0 2 0 0 2 2 2 1 Pre-SET motif SNF2_N PF00176.18 EIW85115.1 - 2.2e-68 230.2 0.0 3.3e-68 229.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EIW85115.1 - 5.8e-35 120.8 7.3 1e-34 120.0 5.1 1.4 1 0 0 1 1 1 1 Rad54 N terminal Helicase_C PF00271.26 EIW85115.1 - 3.3e-13 49.3 0.0 7.1e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EIW85115.1 - 1.9e-07 30.1 0.0 6.3e-07 28.4 0.0 1.7 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EIW85115.1 - 0.015 15.1 0.0 0.089 12.6 0.0 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIW85115.1 - 0.036 14.2 0.3 0.25 11.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain GYF PF02213.11 EIW85116.1 - 1e-06 28.2 0.5 2.2e-06 27.1 0.4 1.6 1 0 0 1 1 1 1 GYF domain Chromo PF00385.19 EIW85117.1 - 3.1e-06 26.7 0.5 5.6e-06 25.9 0.4 1.4 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Herpes_gE PF02480.11 EIW85118.1 - 0.071 11.3 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1049 PF06305.6 EIW85118.1 - 0.14 11.6 1.1 0.26 10.7 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Auxin_repressed PF05564.7 EIW85118.1 - 3 8.4 10.3 0.13 12.8 0.8 2.4 1 1 1 2 2 2 0 Dormancy/auxin associated protein Nuc_sug_transp PF04142.10 EIW85119.1 - 1.7e-78 263.0 14.6 2.6e-78 262.5 10.1 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 EIW85119.1 - 7.9e-09 35.7 16.8 2.9e-08 33.9 0.3 2.7 2 0 0 2 2 2 1 Multidrug resistance efflux transporter UAA PF08449.6 EIW85119.1 - 1.4e-07 30.7 12.6 2e-07 30.2 8.7 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EIW85119.1 - 0.00014 21.8 4.1 0.00014 21.8 2.9 3.0 2 2 0 2 2 2 1 EamA-like transporter family TPT PF03151.11 EIW85119.1 - 0.00023 20.8 26.0 0.00055 19.6 2.6 3.3 2 2 0 2 2 2 2 Triose-phosphate Transporter family DUF4112 PF13430.1 EIW85120.1 - 1.5e-30 105.2 0.1 2e-30 104.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) PNTB PF02233.11 EIW85121.1 - 7e-167 555.8 21.4 7e-167 555.8 14.8 1.8 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EIW85121.1 - 1.8e-52 177.3 0.8 3.8e-52 176.2 0.6 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EIW85121.1 - 3.7e-46 156.5 0.1 1.1e-45 154.9 0.1 1.9 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EIW85121.1 - 2.6e-32 110.8 4.1 2.6e-32 110.8 2.8 5.2 5 1 0 5 5 5 1 Domain of unknown function (DUF3814) ADH_zinc_N PF00107.21 EIW85121.1 - 0.0029 17.1 2.3 0.013 15.0 0.3 2.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIW85121.1 - 0.0059 15.7 2.0 2.4 7.2 0.1 4.0 2 1 1 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 EIW85121.1 - 0.024 14.5 0.5 0.073 12.9 0.3 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_31 PF13847.1 EIW85121.1 - 0.025 14.1 0.0 0.065 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TPP_enzyme_M PF00205.17 EIW85121.1 - 0.039 13.6 0.3 0.18 11.5 0.2 2.3 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain Shikimate_DH PF01488.15 EIW85121.1 - 2.1 8.4 7.1 17 5.5 0.1 4.0 4 0 0 4 4 4 0 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 EIW85121.1 - 2.8 8.0 8.5 0.21 11.6 0.4 3.2 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain MFS_1 PF07690.11 EIW85122.1 - 8.5e-20 70.7 47.7 4.4e-17 61.8 22.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF373 PF04123.8 EIW85122.1 - 0.069 12.1 0.1 0.15 11.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF4231 PF14015.1 EIW85122.1 - 0.67 9.9 5.1 1.3 9.0 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Condensation PF00668.15 EIW85123.1 - 3.7e-08 32.5 0.1 5.3e-08 32.0 0.1 1.1 1 0 0 1 1 1 1 Condensation domain AATase PF07247.7 EIW85123.1 - 0.15 10.5 0.0 0.2 10.1 0.0 1.2 1 0 0 1 1 1 0 Alcohol acetyltransferase Med16 PF11635.3 EIW85124.1 - 3.7e-12 45.0 3.2 6.3e-10 37.6 0.9 2.5 3 0 0 3 3 3 2 Mediator complex subunit 16 DUF2665 PF11654.3 EIW85126.1 - 1e-15 57.0 0.0 1.3e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2665) NatB_MDM20 PF09797.4 EIW85127.1 - 1.2e-68 231.4 7.5 1.4e-67 227.9 1.9 2.4 2 0 0 2 2 2 2 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_14 PF13428.1 EIW85127.1 - 3.1e-07 30.4 0.7 19 6.2 0.0 6.3 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EIW85127.1 - 1.9e-06 28.1 5.9 0.00062 20.0 0.0 4.0 3 1 2 5 5 5 3 Tetratricopeptide repeat BTAD PF03704.12 EIW85127.1 - 2.8e-05 24.4 2.4 0.00042 20.6 0.0 3.4 2 2 2 4 4 4 1 Bacterial transcriptional activator domain RPA_C PF08784.6 EIW85128.1 - 9.9e-14 51.6 0.0 2e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EIW85128.1 - 1.9e-06 27.5 0.0 3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain ATG_C PF09333.6 EIW85129.1 - 2.8e-32 110.7 0.4 8.1e-32 109.2 0.3 1.9 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 EIW85129.1 - 2.2e-09 36.8 0.0 2.5e-08 33.4 0.0 2.4 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG2_CAD PF13329.1 EIW85129.1 - 9.1e-05 22.0 0.6 0.00043 19.8 0.1 2.2 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif Ribosomal_L24e PF01246.15 EIW85130.1 - 5.4e-31 106.2 3.2 8.2e-31 105.6 2.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L24e zf-FCS PF06467.9 EIW85130.1 - 0.011 15.2 5.0 0.021 14.4 3.5 1.4 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif Cid2 PF09774.4 EIW85130.1 - 0.052 13.6 0.2 0.055 13.5 0.1 1.1 1 0 0 1 1 1 0 Caffeine-induced death protein 2 K_oxygenase PF13434.1 EIW85131.1 - 9.8e-92 307.4 0.0 1.5e-91 306.9 0.0 1.2 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EIW85131.1 - 6.8e-11 42.6 0.0 1.4e-09 38.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIW85131.1 - 1e-07 31.8 0.0 2.3e-05 24.2 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EIW85131.1 - 3.5e-07 30.3 0.0 5e-05 23.2 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW85131.1 - 0.00014 20.8 0.0 0.0038 16.1 0.0 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW85131.1 - 0.0059 16.9 0.0 3.4 8.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AMP-binding PF00501.23 EIW85132.1 - 4.7e-91 305.2 0.0 7.9e-91 304.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EIW85132.1 - 5.9e-90 301.1 9.2 6.2e-33 113.9 0.5 3.9 4 0 0 4 4 4 3 Condensation domain PP-binding PF00550.20 EIW85132.1 - 2.3e-30 104.6 0.4 3.3e-13 49.6 0.0 3.8 3 0 0 3 3 3 3 Phosphopantetheine attachment site GH3 PF03321.8 EIW85132.1 - 0.0035 15.9 0.0 0.065 11.7 0.0 2.2 2 0 0 2 2 2 1 GH3 auxin-responsive promoter AMP-binding_C PF13193.1 EIW85132.1 - 0.021 15.7 0.2 0.15 13.0 0.1 2.7 2 1 0 2 2 2 0 AMP-binding enzyme C-terminal domain RII_binding_1 PF10522.4 EIW85132.1 - 3.5 8.1 7.7 0.96 9.8 2.3 2.5 2 0 0 2 2 2 0 RII binding domain SH2_2 PF14633.1 EIW85133.1 - 2.6e-66 222.8 0.4 2.6e-66 222.8 0.3 2.1 2 0 0 2 2 2 1 SH2 domain HHH_7 PF14635.1 EIW85133.1 - 3.7e-31 107.2 0.1 7.9e-31 106.2 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 EIW85133.1 - 2e-28 98.8 0.1 1.8e-16 60.0 0.1 2.7 2 0 0 2 2 2 2 Holliday-junction resolvase-like of SPT6 DLD PF14878.1 EIW85133.1 - 2.4e-28 98.5 3.3 2.4e-28 98.5 2.3 3.5 3 0 0 3 3 3 1 Death-like domain of SPT6 SPT6_acidic PF14632.1 EIW85133.1 - 3.1e-20 72.1 34.4 3.1e-20 72.1 23.8 5.0 3 1 2 5 5 5 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 EIW85133.1 - 4e-14 52.6 0.1 1.5e-13 50.8 0.1 2.0 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 EIW85133.1 - 2.7e-05 23.8 0.0 0.0004 20.1 0.0 2.4 2 0 0 2 2 2 1 SH2 domain S1 PF00575.18 EIW85133.1 - 3.4e-05 23.8 1.4 8.4e-05 22.5 1.0 1.7 1 0 0 1 1 1 1 S1 RNA binding domain HHH_3 PF12836.2 EIW85133.1 - 0.0005 19.9 0.1 0.0015 18.4 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif SRP54 PF00448.17 EIW85134.1 - 5.4e-74 247.8 1.8 9.3e-74 247.1 1.3 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EIW85134.1 - 3.3e-22 78.7 0.6 3.3e-22 78.7 0.4 4.5 3 2 2 5 5 4 1 Signal peptide binding domain SRP54_N PF02881.14 EIW85134.1 - 6.4e-14 51.8 5.5 1.3e-13 50.8 3.8 1.6 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.1 EIW85134.1 - 6.1e-07 29.4 0.1 1.3e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain cobW PF02492.14 EIW85134.1 - 1e-06 28.2 0.3 2.5e-06 27.0 0.2 1.6 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CbiA PF01656.18 EIW85134.1 - 0.00028 20.3 0.3 0.0017 17.8 0.2 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EIW85134.1 - 0.00066 19.4 0.1 0.0014 18.2 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ArgK PF03308.11 EIW85134.1 - 0.0016 17.2 0.7 0.0016 17.2 0.5 2.2 3 0 0 3 3 3 1 ArgK protein AAA_31 PF13614.1 EIW85134.1 - 0.014 15.2 0.0 9.6 6.1 0.0 3.1 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 EIW85134.1 - 0.02 13.9 0.1 0.045 12.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EIW85134.1 - 0.054 14.3 0.0 0.13 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2201 PF09967.4 EIW85134.1 - 0.062 13.3 2.0 0.44 10.5 0.2 3.0 2 1 1 3 3 3 0 VWA-like domain (DUF2201) 6PF2K PF01591.13 EIW85134.1 - 0.1 11.6 0.0 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 6-phosphofructo-2-kinase WD40 PF00400.27 EIW85135.1 - 3.7e-13 48.7 24.4 0.025 14.4 0.5 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat YL1 PF05764.8 EIW85135.1 - 0.069 12.7 8.9 0.14 11.7 6.1 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Lin-8 PF03353.10 EIW85135.1 - 0.83 8.8 17.0 0.03 13.5 6.6 1.9 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Methyltransf_23 PF13489.1 EIW85136.1 - 2.2e-13 50.2 0.0 3e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW85136.1 - 6.1e-08 33.0 0.0 1.5e-07 31.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 EIW85136.1 - 1.2e-06 27.1 0.0 1.6e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.1 EIW85136.1 - 4.8e-06 26.2 0.0 6.2e-05 22.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW85136.1 - 6e-05 23.5 0.1 0.001 19.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW85136.1 - 0.00054 19.9 0.1 0.0019 18.2 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW85136.1 - 0.0087 16.5 0.0 0.045 14.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW85136.1 - 0.019 15.2 0.0 0.054 13.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EIW85136.1 - 0.046 12.8 0.0 0.12 11.4 0.0 1.6 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EIW85136.1 - 0.071 13.0 0.0 0.48 10.3 0.0 2.0 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_8 PF05148.10 EIW85136.1 - 0.097 12.2 0.0 0.36 10.4 0.0 1.9 1 1 0 1 1 1 0 Hypothetical methyltransferase RRM_1 PF00076.17 EIW85137.1 - 1.3e-83 274.6 3.0 5.9e-22 77.0 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW85137.1 - 4.1e-58 193.2 0.2 5.7e-15 55.0 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW85137.1 - 5e-44 147.9 0.0 1.6e-11 43.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EIW85137.1 - 8.7e-26 89.3 3.0 1.1e-25 89.1 1.1 1.9 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 EIW85137.1 - 1.9e-05 24.4 7.1 0.064 13.1 1.5 3.6 4 0 0 4 4 4 2 RNA binding motif OB_RNB PF08206.6 EIW85137.1 - 0.0003 20.2 0.5 5.7 6.5 0.0 3.5 3 0 0 3 3 3 2 Ribonuclease B OB domain Limkain-b1 PF11608.3 EIW85137.1 - 0.00064 19.4 1.5 1.8 8.3 0.1 3.5 2 1 1 3 3 3 2 Limkain b1 CbiG_mid PF11761.3 EIW85137.1 - 0.0097 16.1 0.1 0.43 10.8 0.0 3.1 3 0 0 3 3 3 1 Cobalamin biosynthesis central region DUF1494 PF07379.6 EIW85137.1 - 0.033 14.1 0.0 6.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1494) PNPase PF03726.9 EIW85137.1 - 0.033 14.4 1.8 0.22 11.8 0.0 2.5 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Nup35_RRM_2 PF14605.1 EIW85137.1 - 0.033 13.9 0.1 4.3 7.1 0.0 3.6 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif CSD PF00313.17 EIW85137.1 - 0.066 12.9 0.4 16 5.3 0.0 3.3 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain YflT PF11181.3 EIW85137.1 - 0.24 11.5 3.8 2.3 8.4 0.6 2.9 3 0 0 3 3 3 0 Heat induced stress protein YflT SCAMP PF04144.8 EIW85138.1 - 1.1e-46 158.9 7.3 1.3e-46 158.7 5.1 1.0 1 0 0 1 1 1 1 SCAMP family Pheromone PF08015.6 EIW85138.1 - 0.37 11.6 1.7 0.64 10.8 1.2 1.3 1 0 0 1 1 1 0 Fungal mating-type pheromone DPBB_1 PF03330.13 EIW85139.1 - 5.2e-10 39.1 0.9 1.3e-09 37.8 0.6 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EIW85139.1 - 1.6e-06 27.8 0.7 2.9e-06 26.9 0.5 1.5 1 0 0 1 1 1 1 Barwin family NAD_binding_10 PF13460.1 EIW85140.1 - 6.4e-13 49.1 0.0 5.1e-11 42.9 0.0 2.3 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EIW85140.1 - 1.8e-10 40.6 0.0 6.2e-07 29.0 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIW85140.1 - 0.0002 20.1 0.0 0.0078 14.9 0.0 2.2 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EIW85140.1 - 0.004 16.1 0.1 1.3 7.8 0.0 3.1 2 1 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EIW85140.1 - 0.098 12.5 0.1 0.22 11.4 0.0 1.6 1 1 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 EIW85140.1 - 0.14 11.0 0.0 0.4 9.5 0.0 1.8 2 0 0 2 2 2 0 RmlD substrate binding domain ADK PF00406.17 EIW85141.1 - 1.7e-43 148.1 0.0 2.2e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EIW85141.1 - 1e-11 44.2 0.0 1.8e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EIW85141.1 - 2e-05 25.3 0.0 3.1e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIW85141.1 - 0.00025 21.3 0.0 0.00049 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW85141.1 - 0.00026 20.8 0.0 0.00041 20.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIW85141.1 - 0.022 13.8 0.0 0.033 13.3 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 EIW85141.1 - 0.092 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain Swi3 PF07962.7 EIW85142.1 - 9.1e-24 82.8 0.1 1.4e-23 82.3 0.1 1.3 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Inhibitor_I53 PF11714.3 EIW85142.1 - 0.006 16.5 0.4 0.038 13.9 0.0 2.4 2 0 0 2 2 2 1 Thrombin inhibitor Madanin WD40 PF00400.27 EIW85143.1 - 1.3e-16 59.7 10.9 2.4e-05 24.0 0.2 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat MMS1_N PF10433.4 EIW85143.1 - 0.00033 18.9 0.3 0.45 8.6 0.1 2.1 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term PLRV_ORF5 PF01690.12 EIW85143.1 - 3.9 6.4 8.5 5.4 6.0 5.9 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SAP PF02037.22 EIW85145.1 - 7.9e-06 25.2 0.1 0.021 14.3 0.0 2.6 2 0 0 2 2 2 2 SAP domain DUF2315 PF10231.4 EIW85146.1 - 5.7e-12 45.6 10.1 1.2e-09 38.1 4.6 2.1 1 1 1 2 2 2 2 Uncharacterised conserved protein (DUF2315) Nucleoporin_C PF03177.9 EIW85147.1 - 2.5e-54 184.8 0.8 2.5e-54 184.8 0.5 1.5 2 0 0 2 2 2 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EIW85147.1 - 3.4e-26 91.9 0.0 4.7e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Histone PF00125.19 EIW85148.1 - 7.3e-18 64.4 0.7 1.2e-17 63.8 0.5 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIW85148.1 - 0.0012 18.8 0.1 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.8 EIW85148.1 - 0.033 13.6 0.1 0.066 12.6 0.1 1.5 1 1 0 1 1 1 0 Replication protein C N-terminal domain MaoC_dehydratas PF01575.14 EIW85149.1 - 0.055 12.8 0.3 0.1 12.0 0.0 1.6 2 0 0 2 2 2 0 MaoC like domain SLY PF12485.3 EIW85149.1 - 0.067 13.4 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein Methyltransf_11 PF08241.7 EIW85150.1 - 4.7e-13 49.4 0.0 8.4e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW85150.1 - 4.8e-07 29.6 0.0 7.5e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW85150.1 - 3.6e-06 27.3 0.0 6.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW85150.1 - 1.5e-05 25.5 0.0 4.9e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW85150.1 - 1.6e-05 24.9 0.0 3.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW85150.1 - 0.00022 20.8 0.0 0.026 14.1 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW85150.1 - 0.0041 17.4 0.0 0.015 15.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW85150.1 - 0.019 14.1 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 EIW85150.1 - 0.048 13.0 0.0 0.94 8.8 0.0 2.1 1 1 1 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.4 EIW85150.1 - 0.077 12.4 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.15 EIW85150.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase DAGK_cat PF00781.19 EIW85152.1 - 4.4e-22 77.9 0.0 7.2e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.16 EIW85152.1 - 0.047 12.4 0.0 0.084 11.6 0.0 1.3 1 0 0 1 1 1 0 ATP-NAD kinase Histone PF00125.19 EIW85153.1 - 2.5e-22 78.7 0.2 3.5e-22 78.3 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EIW85153.1 - 1.2e-05 25.2 0.1 3.2e-05 23.8 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EIW85153.1 - 0.00037 20.7 0.0 0.00065 19.9 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 EIW85153.1 - 0.027 13.9 0.5 0.047 13.1 0.1 1.6 1 1 1 2 2 2 0 Replication protein C N-terminal domain DUF1018 PF06252.7 EIW85153.1 - 0.028 14.9 1.1 0.038 14.5 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) DUF3408 PF11888.3 EIW85153.1 - 0.7 9.8 4.0 1.1 9.1 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) MSA-2c PF12238.3 EIW85153.1 - 1.1 8.8 6.1 4.1 7.0 3.5 1.9 2 0 0 2 2 2 0 Merozoite surface antigen 2c Pkinase PF00069.20 EIW85155.1 - 2.3e-71 240.0 0.0 3.5e-71 239.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW85155.1 - 3.4e-47 160.6 0.0 5.1e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EIW85155.1 - 1.7e-16 60.0 0.0 3.5e-16 59.0 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 SAM_2 PF07647.12 EIW85155.1 - 5.7e-16 58.1 0.0 1.2e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EIW85155.1 - 5.4e-15 55.3 0.0 1.2e-14 54.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Kinase-like PF14531.1 EIW85155.1 - 5.1e-06 25.6 0.0 0.00018 20.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like BSP_II PF05432.6 EIW85155.1 - 0.12 11.6 11.0 0.19 10.9 7.7 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Seadorna_VP7 PF07387.6 EIW85155.1 - 0.17 10.6 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 TRM PF02005.11 EIW85156.1 - 2e-120 402.1 0.0 3.7e-120 401.3 0.0 1.4 1 1 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase MTS PF05175.9 EIW85156.1 - 0.13 11.5 0.1 0.42 9.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain NAD_binding_6 PF08030.7 EIW85157.1 - 2.4e-14 53.5 0.0 7.6e-07 29.1 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EIW85157.1 - 1.2e-12 47.5 0.0 7.6e-12 45.0 0.0 2.3 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 EIW85157.1 - 2.4e-12 47.0 22.7 6.1e-12 45.7 12.8 2.6 2 1 0 2 2 2 1 Ferric reductase like transmembrane component HMA PF00403.21 EIW85158.1 - 1.8e-16 59.9 0.7 2e-16 59.8 0.5 1.0 1 0 0 1 1 1 1 Heavy-metal-associated domain AA_permease_2 PF13520.1 EIW85159.1 - 3.5e-65 220.2 43.4 4.3e-65 219.9 30.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIW85159.1 - 1.8e-33 115.6 37.7 2.5e-33 115.1 26.2 1.1 1 0 0 1 1 1 1 Amino acid permease DUF3290 PF11694.3 EIW85159.1 - 0.077 12.7 0.9 0.23 11.1 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) RNase_PH PF01138.16 EIW85160.1 - 3.6e-34 117.9 0.1 6.7e-34 117.0 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EIW85160.1 - 3.2e-05 23.7 0.0 5.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Pkinase PF00069.20 EIW85161.1 - 3e-15 56.0 0.0 7.2e-14 51.5 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW85161.1 - 6.2e-07 28.7 0.0 8.3e-07 28.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EIW85161.1 - 2.4e-05 23.7 0.2 4.7e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EIW85161.1 - 0.00065 18.8 0.3 0.0014 17.7 0.2 1.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EIW85161.1 - 0.012 14.6 0.0 0.018 14.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EIW85161.1 - 0.11 12.1 0.2 0.24 11.1 0.2 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family RRM_1 PF00076.17 EIW85162.1 - 1.9e-16 59.4 0.0 6e-16 57.8 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW85162.1 - 5.7e-14 51.8 0.0 8.7e-14 51.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW85162.1 - 3.6e-09 36.3 0.0 1.7e-08 34.1 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.8 EIW85162.1 - 0.03 14.0 0.0 0.064 13.0 0.0 1.7 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif TFIID-18kDa PF02269.11 EIW85163.1 - 1.8e-18 66.1 0.0 2e-18 65.9 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit DUF4211 PF13926.1 EIW85164.1 - 2e-27 95.5 0.0 5.4e-27 94.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4211) C1_1 PF00130.17 EIW85165.1 - 0.0011 18.7 2.7 0.0011 18.7 1.9 3.1 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) UNC-79 PF14776.1 EIW85165.1 - 0.004 15.5 0.0 0.0074 14.7 0.0 1.3 1 0 0 1 1 1 1 Cation-channel complex subunit UNC-79 TRAPPC9-Trs120 PF08626.6 EIW85166.1 - 3e-116 389.2 0.0 3.4e-87 293.0 0.0 2.1 2 0 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Porin_3 PF01459.17 EIW85167.1 - 6.1e-79 265.1 2.6 7e-79 264.9 1.8 1.0 1 0 0 1 1 1 1 Eukaryotic porin Glyco_transf_15 PF01793.11 EIW85168.1 - 2.7e-123 411.1 14.2 3.1e-123 410.9 9.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Glyco_transf_15 PF01793.11 EIW85169.1 - 5.6e-139 462.6 1.0 6.7e-139 462.4 0.7 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase PI3_PI4_kinase PF00454.22 EIW85170.1 - 4.6e-33 114.6 0.0 8.2e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.1 EIW85170.1 - 0.097 11.6 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) CDC45 PF02724.9 EIW85170.1 - 2.1 6.2 5.3 3.1 5.7 3.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Sec16_C PF12931.2 EIW85171.1 - 1.1e-68 232.1 0.0 1.4e-68 231.7 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 EIW85171.1 - 1.8e-27 95.6 0.0 4.8e-27 94.2 0.0 1.8 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region PUF PF00806.14 EIW85172.1 - 4e-65 211.7 5.4 5.6e-09 34.9 0.0 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat NABP PF07990.7 EIW85172.1 - 0.038 13.2 0.0 0.067 12.4 0.0 1.4 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Kinesin PF00225.18 EIW85173.1 - 2.2e-111 371.8 0.3 5.2e-111 370.5 0.2 1.7 1 0 0 1 1 1 1 Kinesin motor domain Filament PF00038.16 EIW85173.1 - 3.5 7.0 72.2 0.5 9.7 29.0 3.7 3 1 1 4 4 4 0 Intermediate filament protein DASH_Dam1 PF08653.5 EIW85173.1 - 9.3 6.1 8.5 16 5.3 0.1 3.9 3 0 0 3 3 3 0 DASH complex subunit Dam1 Elf1 PF05129.8 EIW85174.1 - 5.3e-28 96.5 0.5 7e-28 96.1 0.3 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-CHY PF05495.7 EIW85174.1 - 0.0038 17.3 0.3 0.0057 16.7 0.2 1.3 1 0 0 1 1 1 1 CHY zinc finger zf-Sec23_Sec24 PF04810.10 EIW85174.1 - 0.035 13.6 0.5 0.35 10.4 0.1 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger Ima1_N PF09779.4 EIW85174.1 - 0.05 14.0 0.1 0.069 13.6 0.1 1.2 1 0 0 1 1 1 0 Ima1 N-terminal domain Cytochrome_C554 PF13435.1 EIW85174.1 - 0.076 13.0 1.8 0.19 11.7 1.2 1.7 1 1 0 1 1 1 0 Cytochrome c554 and c-prime Cytochrom_c3_2 PF14537.1 EIW85174.1 - 0.12 12.7 0.9 0.2 12.0 0.5 1.5 1 1 0 1 1 1 0 Cytochrome c3 Kinesin PF00225.18 EIW85175.1 - 4.8e-109 364.1 0.0 2e-108 362.0 0.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain Lectin_N PF03954.9 EIW85175.1 - 0.0019 17.6 2.4 0.0019 17.6 1.7 4.0 4 1 0 4 4 4 1 Hepatic lectin, N-terminal domain DUF2580 PF10824.3 EIW85175.1 - 3.1 8.2 20.3 0.18 12.1 3.3 4.5 3 2 2 5 5 5 0 Protein of unknown function (DUF2580) Allexi_40kDa PF05549.6 EIW85175.1 - 7.5 5.7 22.8 0.83 8.8 2.1 3.6 2 1 0 3 3 3 0 Allexivirus 40kDa protein F-box PF00646.28 EIW85176.1 - 2.3e-09 36.6 2.7 4.8e-09 35.6 1.9 1.5 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW85176.1 - 0.00041 20.0 2.0 0.0012 18.5 1.4 1.8 1 0 0 1 1 1 1 F-box-like Vps55 PF04133.9 EIW85177.1 - 1.8e-41 140.6 4.0 2.1e-41 140.4 2.8 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 BCLP PF12304.3 EIW85177.1 - 0.038 13.3 3.7 0.083 12.3 1.6 1.8 1 1 1 2 2 2 0 Beta-casein like protein STT3 PF02516.9 EIW85177.1 - 0.11 11.4 3.0 0.15 10.9 2.1 1.2 1 0 0 1 1 1 0 Oligosaccharyl transferase STT3 subunit zf-CCCH PF00642.19 EIW85178.1 - 0.011 15.4 0.9 0.017 14.7 0.6 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF972 PF06156.8 EIW85178.1 - 7.6 6.9 8.4 4.6 7.6 0.3 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF972) PAP2 PF01569.16 EIW85179.1 - 1.7e-11 43.8 8.6 3e-11 43.1 6.0 1.4 1 0 0 1 1 1 1 PAP2 superfamily DUF3552 PF12072.3 EIW85180.1 - 0.011 15.0 1.4 0.011 15.0 1.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3552) DUF3328 PF11807.3 EIW85180.1 - 0.04 13.5 6.2 0.17 11.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) DUF3357 PF11837.3 EIW85180.1 - 0.077 12.8 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) PBP1_TM PF14812.1 EIW85180.1 - 0.76 10.1 6.7 10 6.4 0.0 3.2 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC27 PF09507.5 EIW85180.1 - 0.8 8.8 7.3 3.1 6.9 5.0 1.8 1 1 0 1 1 1 0 DNA polymerase subunit Cdc27 Pmp3 PF01679.12 EIW85181.1 - 4e-17 61.6 4.2 5.1e-17 61.3 2.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator rve_3 PF13683.1 EIW85181.1 - 0.0083 15.6 1.3 0.029 13.8 0.8 2.0 2 0 0 2 2 2 1 Integrase core domain eIF-4B PF06273.6 EIW85181.1 - 0.051 12.3 20.3 0.068 11.9 14.0 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B NST1 PF13945.1 EIW85181.1 - 1.6 8.7 9.6 0.29 11.1 2.0 2.3 2 0 0 2 2 2 0 Salt tolerance down-regulator zf-H2C2_2 PF13465.1 EIW85182.1 - 2.5e-23 81.1 23.5 5e-07 29.6 1.6 5.4 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 EIW85182.1 - 1.5e-19 69.0 30.4 7.7e-06 25.9 0.7 4.9 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW85182.1 - 4.9e-15 54.6 20.5 0.00025 21.1 0.5 4.8 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIW85182.1 - 2e-07 30.9 2.0 0.13 12.4 0.0 4.6 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EIW85182.1 - 6.3e-06 25.8 9.3 0.2 11.5 0.0 4.2 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.2 EIW85182.1 - 0.0018 18.3 4.1 0.79 10.0 0.1 4.1 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-TRAF PF02176.13 EIW85182.1 - 0.22 11.9 10.2 0.11 12.9 0.7 2.9 1 1 2 3 3 3 0 TRAF-type zinc finger Ogr_Delta PF04606.7 EIW85182.1 - 0.43 10.2 4.3 2.8 7.6 0.1 3.2 2 1 1 3 3 3 0 Ogr/Delta-like zinc finger zf-CGNR PF11706.3 EIW85182.1 - 4.6 6.8 7.3 18 4.9 0.1 3.7 4 0 0 4 4 4 0 CGNR zinc finger FBPase PF00316.15 EIW85183.1 - 1.2e-127 425.2 0.1 1.4e-127 425.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 EIW85183.1 - 8.4e-06 25.2 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Inositol monophosphatase family bZIP_2 PF07716.10 EIW85184.1 - 4.9e-09 35.8 15.2 4.9e-09 35.8 10.5 1.5 2 0 0 2 2 2 1 Basic region leucine zipper XhlA PF10779.4 EIW85184.1 - 0.00034 20.4 0.0 0.00056 19.7 0.0 1.3 1 0 0 1 1 1 1 Haemolysin XhlA bZIP_1 PF00170.16 EIW85184.1 - 0.00037 20.3 14.5 0.00037 20.3 10.0 2.1 2 1 0 2 2 2 1 bZIP transcription factor PAT1 PF09770.4 EIW85184.1 - 0.0015 16.9 27.8 0.0019 16.5 19.2 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 SR-25 PF10500.4 EIW85184.1 - 0.0098 15.3 4.5 0.017 14.5 3.1 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein TSC22 PF01166.13 EIW85184.1 - 0.035 14.0 0.1 0.092 12.7 0.0 1.8 1 0 0 1 1 1 0 TSC-22/dip/bun family CASP_C PF08172.7 EIW85184.1 - 0.18 10.7 3.7 0.37 9.7 2.6 1.6 1 1 0 1 1 1 0 CASP C terminal DUF2418 PF10332.4 EIW85185.1 - 2.7e-18 66.0 0.0 5e-18 65.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2418) DUF2457 PF10446.4 EIW85185.1 - 0.53 8.9 7.5 3.2 6.3 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) PNGaseA PF12222.3 EIW85186.1 - 1.8e-79 267.6 6.8 2.5e-79 267.1 4.7 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A HTH_45 PF14947.1 EIW85186.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Winged helix-turn-helix DUF2283 PF10049.4 EIW85186.1 - 0.15 11.8 0.1 0.41 10.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2283) FTHFS PF01268.14 EIW85187.1 - 3.6e-256 850.5 0.0 4.6e-256 850.1 0.0 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EIW85187.1 - 8.9e-66 219.9 1.2 8.9e-66 219.9 0.9 1.8 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EIW85187.1 - 1.6e-34 118.3 0.0 3.1e-34 117.4 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GrpE PF01025.14 EIW85188.1 - 3.6e-45 153.4 0.2 4.7e-45 153.1 0.1 1.1 1 0 0 1 1 1 1 GrpE BicD PF09730.4 EIW85188.1 - 0.0029 16.0 2.2 0.0033 15.8 1.5 1.1 1 0 0 1 1 1 1 Microtubule-associated protein Bicaudal-D ADIP PF11559.3 EIW85188.1 - 0.046 13.6 4.8 0.074 12.9 3.3 1.3 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EIW85188.1 - 0.22 11.0 3.3 0.26 10.8 2.3 1.2 1 0 0 1 1 1 0 IncA protein tRNA-synt_2d PF01409.15 EIW85189.1 - 1.4e-45 155.4 0.0 5e-24 84.8 0.0 2.2 1 1 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EIW85189.1 - 1.4e-24 86.0 0.0 3.4e-24 84.8 0.0 1.7 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain tRNA-synt_2 PF00152.15 EIW85189.1 - 0.18 10.5 0.3 14 4.3 0.0 2.5 3 0 0 3 3 3 0 tRNA synthetases class II (D, K and N) GCIP PF13324.1 EIW85191.1 - 8.6e-12 44.8 0.0 1.6e-11 43.9 0.0 1.4 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting PKI PF02827.11 EIW85191.1 - 0.0064 16.5 0.1 0.022 14.8 0.0 1.9 1 0 0 1 1 1 1 cAMP-dependent protein kinase inhibitor Cytochrom_B562 PF07361.6 EIW85191.1 - 0.048 14.0 0.2 1.5 9.2 0.0 2.5 2 0 0 2 2 2 0 Cytochrome b562 Peptidase_M41 PF01434.13 EIW85192.1 - 1.9e-65 220.3 0.0 3e-65 219.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EIW85192.1 - 8.7e-43 145.6 0.0 2.5e-42 144.2 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EIW85192.1 - 1.2e-05 25.0 0.1 8.5e-05 22.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EIW85192.1 - 4.1e-05 22.7 0.1 0.00013 21.1 0.0 1.8 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EIW85192.1 - 4.3e-05 24.3 0.0 0.00016 22.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EIW85192.1 - 0.00012 22.0 7.9 0.0054 16.7 0.1 4.6 3 2 2 5 5 5 1 AAA ATPase domain TIP49 PF06068.8 EIW85192.1 - 0.00022 20.0 0.1 0.00041 19.1 0.1 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EIW85192.1 - 0.00034 20.3 1.4 0.00081 19.0 0.2 2.2 2 0 0 2 2 1 1 Part of AAA domain AAA_22 PF13401.1 EIW85192.1 - 0.00037 20.6 2.1 0.006 16.7 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EIW85192.1 - 0.00041 19.8 1.1 0.016 14.6 0.3 2.7 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 EIW85192.1 - 0.0018 18.1 0.0 0.0068 16.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EIW85192.1 - 0.0018 17.7 0.0 0.0035 16.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 EIW85192.1 - 0.0022 17.9 0.1 0.0063 16.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EIW85192.1 - 0.0042 16.2 0.3 0.0092 15.1 0.2 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EIW85192.1 - 0.007 15.4 0.0 0.017 14.2 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.7 EIW85192.1 - 0.0077 15.9 0.1 0.15 11.6 0.1 2.5 2 0 0 2 2 2 1 NACHT domain AAA_2 PF07724.9 EIW85192.1 - 0.013 15.3 0.0 0.037 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EIW85192.1 - 0.017 15.4 0.1 0.061 13.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EIW85192.1 - 0.017 14.9 0.0 0.051 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EIW85192.1 - 0.039 12.8 0.0 0.073 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF1227 PF06777.6 EIW85193.1 - 7.7e-58 194.3 0.1 1.4e-57 193.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EIW85193.1 - 2.7e-47 160.4 0.1 4.7e-47 159.6 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EIW85193.1 - 1e-44 152.4 0.0 2.1e-44 151.4 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD PF00270.24 EIW85193.1 - 0.00015 21.2 0.2 0.029 13.8 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.18 EIW85193.1 - 0.00085 18.2 0.2 0.011 14.5 0.1 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EIW85193.1 - 0.0052 16.6 0.1 0.18 11.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EIW85193.1 - 0.045 12.7 0.1 4.5 6.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.1 EIW85193.1 - 0.054 13.6 0.1 7.1 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Cellulase PF00150.13 EIW85194.1 - 3.2e-18 65.9 0.7 1.2e-17 64.0 0.3 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 EIW85194.1 - 3.5e-09 36.2 0.1 9.4e-06 24.9 0.0 2.5 2 1 0 2 2 2 2 Beta-galactosidase Cellulase-like PF12876.2 EIW85194.1 - 6.5e-06 26.5 0.0 1.5e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Sugar-binding cellulase-like DUF4038 PF13204.1 EIW85194.1 - 3.3e-05 23.3 0.0 0.001 18.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4038) TPR_12 PF13424.1 EIW85195.1 - 1.1e-08 34.9 0.7 0.049 13.5 0.0 4.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EIW85195.1 - 9.8e-05 21.9 1.7 0.051 13.5 0.0 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EIW85195.1 - 0.00021 20.8 0.0 0.45 10.4 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIW85195.1 - 0.00039 20.0 0.0 0.44 10.2 0.0 3.0 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 EIW85195.1 - 0.0042 16.6 0.0 3.8 7.2 0.1 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 EIW85195.1 - 0.0094 15.8 0.8 0.18 11.7 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EIW85195.1 - 0.018 15.7 5.3 0.067 13.8 0.0 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIW85195.1 - 0.019 14.7 0.7 14 5.7 0.0 3.9 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF2225 PF09986.4 EIW85195.1 - 0.11 11.9 0.0 0.36 10.2 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_17 PF13431.1 EIW85195.1 - 0.14 12.4 0.0 5 7.5 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIW85195.1 - 0.37 11.5 6.6 6.6 7.6 0.0 5.1 5 1 0 5 5 5 0 Tetratricopeptide repeat Peptidase_M49 PF03571.10 EIW85196.1 - 2e-193 643.4 0.0 2.4e-193 643.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 SpoIIE PF07228.7 EIW85197.1 - 6.3e-11 42.3 0.0 1.3e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EIW85197.1 - 0.017 14.5 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein phosphatase 2C Glucan_synthase PF02364.10 EIW85198.1 - 0 1363.9 0.0 0 1363.2 0.0 1.3 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EIW85198.1 - 1.3e-39 134.7 0.1 3.5e-39 133.3 0.0 1.8 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 RAI16-like PF10257.4 EIW85200.1 - 1.2e-75 254.6 0.3 2.2e-75 253.8 0.2 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein DUF2890 PF11081.3 EIW85200.1 - 0.08 12.9 5.8 0.059 13.4 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) TRIQK PF15168.1 EIW85201.1 - 2.6 8.0 6.4 0.39 10.6 0.5 2.6 2 1 1 3 3 3 0 Triple QxxK/R motif-containing protein family SET PF00856.23 EIW85202.1 - 0.015 15.6 0.0 0.062 13.6 0.0 2.1 1 1 0 1 1 1 0 SET domain adh_short PF00106.20 EIW85203.1 - 3.4e-33 114.9 2.7 4.6e-33 114.4 1.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW85203.1 - 1.7e-14 53.8 0.6 2.3e-14 53.4 0.4 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIW85203.1 - 3.5e-14 53.1 0.1 4.2e-14 52.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EIW85203.1 - 2.7e-05 23.8 1.3 6.8e-05 22.5 0.9 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Helicase_RecD PF05127.9 EIW85203.1 - 0.02 14.5 0.1 0.033 13.8 0.0 1.4 2 0 0 2 2 2 0 Helicase Epimerase PF01370.16 EIW85203.1 - 0.025 14.0 0.5 0.04 13.3 0.4 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EIW85203.1 - 0.063 12.4 0.0 0.086 11.9 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Abhydrolase_6 PF12697.2 EIW85205.1 - 5.7e-18 65.6 1.1 7.9e-18 65.1 0.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW85205.1 - 5.5e-08 32.6 0.1 7.4e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW85205.1 - 3.7e-05 23.5 0.1 0.00012 21.8 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Cutinase PF01083.17 EIW85205.1 - 0.013 15.1 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Cutinase Ndr PF03096.9 EIW85205.1 - 0.1 11.0 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Ndr family DUF915 PF06028.6 EIW85205.1 - 0.18 10.8 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) RWD PF05773.17 EIW85206.1 - 5.1e-17 61.7 0.5 1.6e-16 60.1 0.1 2.0 2 0 0 2 2 2 1 RWD domain Ribosomal_S21 PF01165.15 EIW85207.1 - 7.8e-10 38.0 7.4 7.8e-10 38.0 5.1 1.5 2 0 0 2 2 2 1 Ribosomal protein S21 TetR_C_6 PF13977.1 EIW85207.1 - 0.0072 16.3 1.6 0.0083 16.1 1.1 1.1 1 0 0 1 1 1 1 Bacterial transcriptional repressor DUF1823 PF08853.6 EIW85207.1 - 0.053 13.2 0.1 0.061 13.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1823) ADIP PF11559.3 EIW85207.1 - 0.2 11.5 4.2 0.25 11.2 2.9 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding C8 PF08742.6 EIW85208.1 - 0.13 12.5 2.2 0.2 11.9 1.5 1.4 1 1 0 1 1 1 0 C8 domain Cyclin_N PF00134.18 EIW85209.1 - 2.5e-14 52.9 0.0 4.1e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 EIW85209.1 - 1e-05 25.2 0.1 0.00017 21.3 0.0 2.4 2 0 0 2 2 2 1 Transcription factor TFIIB repeat Cyclin_C PF02984.14 EIW85209.1 - 0.0032 17.3 0.4 2.7 7.9 0.0 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain IF-2B PF01008.12 EIW85211.1 - 6.4e-61 205.8 0.0 1.3e-60 204.8 0.0 1.4 1 1 0 1 1 1 1 Initiation factor 2 subunit family HisKA PF00512.20 EIW85211.1 - 0.11 12.5 0.1 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 His Kinase A (phospho-acceptor) domain Peptidase_M24 PF00557.19 EIW85213.1 - 5.2e-44 150.3 0.0 6.4e-44 150.0 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EIW85213.1 - 2.1e-05 24.2 4.5 5e-05 23.0 3.1 1.7 1 0 0 1 1 1 1 MYND finger Acyltransferase PF01553.16 EIW85214.1 - 3e-12 46.0 0.0 6.5e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase CLASP_N PF12348.3 EIW85215.1 - 3.4e-24 85.4 0.0 8.4e-08 31.8 0.0 5.6 6 0 0 6 6 6 4 CLASP N terminal HEAT_2 PF13646.1 EIW85215.1 - 5.9e-12 45.7 21.4 0.0077 16.4 0.0 9.8 8 2 2 10 10 10 4 HEAT repeats HEAT PF02985.17 EIW85215.1 - 1.6e-11 43.2 14.3 6.3 7.1 0.0 10.8 13 0 0 13 13 13 4 HEAT repeat HEAT_EZ PF13513.1 EIW85215.1 - 9.3e-05 22.8 14.6 5 7.7 0.0 8.8 7 1 1 8 8 8 2 HEAT-like repeat Cnd1 PF12717.2 EIW85215.1 - 0.0065 16.3 0.1 32 4.2 0.0 4.9 5 1 0 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EIW85215.1 - 0.062 13.6 0.0 76 3.7 0.0 5.0 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 EIW85215.1 - 0.099 12.3 2.1 13 5.4 0.0 3.9 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis Arm PF00514.18 EIW85215.1 - 0.17 11.7 1.3 93 3.0 0.0 4.9 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat DUF3730 PF12530.3 EIW85215.1 - 2 8.2 5.9 24 4.7 0.5 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3730) TAN PF11640.3 EIW85215.1 - 3.3 7.4 7.3 1.5 8.5 0.0 4.1 6 1 0 6 6 6 0 Telomere-length maintenance and DNA damage repair Apc5 PF12862.2 EIW85216.1 - 2e-06 27.5 0.0 1.3e-05 24.9 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 EIW85216.1 - 0.00018 21.3 5.5 0.59 10.1 0.2 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 EIW85216.1 - 0.032 14.6 4.3 1.3 9.7 0.4 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EIW85216.1 - 0.19 11.7 5.3 0.11 12.5 0.3 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EIW85216.1 - 0.44 11.3 9.0 1.2 9.9 0.1 5.1 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 EIW85216.1 - 0.62 10.0 4.0 0.68 9.8 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat NOC3p PF07540.6 EIW85217.1 - 1e-27 96.2 0.0 1.4e-26 92.6 0.0 2.5 2 0 0 2 2 2 1 Nucleolar complex-associated protein CBF PF03914.12 EIW85217.1 - 1.3e-24 86.5 2.1 1.5e-24 86.3 0.0 2.2 3 0 0 3 3 3 1 CBF/Mak21 family DUF1843 PF08898.5 EIW85217.1 - 0.7 9.9 4.4 1.9 8.5 3.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1843) UEV PF05743.8 EIW85218.1 - 8.3e-37 125.5 0.0 1.2e-36 125.0 0.0 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EIW85218.1 - 3.5e-27 93.8 2.4 1.6e-26 91.6 0.3 2.2 2 0 0 2 2 2 1 Vps23 core domain Mod_r PF07200.8 EIW85218.1 - 0.17 11.8 0.1 8 6.3 0.0 2.5 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein MSC PF09402.5 EIW85219.1 - 2.2e-51 174.5 0.0 3.1e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EIW85219.1 - 2e-10 40.0 0.0 5.3e-10 38.6 0.0 1.8 2 0 0 2 2 2 1 HeH/LEM domain DUF1019 PF06254.6 EIW85219.1 - 0.028 14.5 0.1 0.75 9.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1019) Pyr_redox_2 PF07992.9 EIW85220.1 - 6.4e-08 32.7 0.0 5.7e-07 29.6 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EIW85220.1 - 0.001 18.8 0.0 0.17 11.6 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EIW85220.1 - 0.0021 18.1 0.8 1 9.4 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.10 EIW85220.1 - 0.0099 15.4 0.1 0.015 14.8 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain DAO PF01266.19 EIW85220.1 - 0.01 14.7 0.5 0.88 8.4 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Chon_Sulph_att PF06566.6 EIW85220.1 - 0.046 13.3 0.0 0.069 12.7 0.0 1.3 1 0 0 1 1 1 0 Chondroitin sulphate attachment domain Trp_halogenase PF04820.9 EIW85220.1 - 0.07 11.7 0.2 0.25 9.9 0.1 1.9 3 0 0 3 3 3 0 Tryptophan halogenase Thi4 PF01946.12 EIW85220.1 - 0.13 11.3 0.0 0.43 9.6 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Cu_bind_like PF02298.12 EIW85221.1 - 4.8e-05 23.0 0.4 0.00018 21.2 0.4 1.9 2 0 0 2 2 2 1 Plastocyanin-like domain Copper-bind PF00127.15 EIW85221.1 - 0.0042 17.2 0.3 0.011 15.9 0.2 1.7 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family DUF4477 PF14780.1 EIW85222.1 - 3.5e-10 39.5 0.0 5.1e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) Adaptin_N PF01602.15 EIW85223.1 - 4e-132 441.2 1.6 5.3e-132 440.8 1.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EIW85223.1 - 9.7e-24 84.1 0.2 2.3e-22 79.6 0.0 2.8 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EIW85223.1 - 5.8e-14 52.1 6.4 1.6e-08 34.6 0.2 5.5 2 1 4 6 6 6 4 HEAT repeats HEAT PF02985.17 EIW85223.1 - 4.4e-10 38.7 5.4 0.0087 16.0 0.0 6.5 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 EIW85223.1 - 0.00066 20.0 5.6 1.9 9.1 0.1 5.6 6 1 1 7 7 7 2 HEAT-like repeat Arm PF00514.18 EIW85223.1 - 0.0012 18.5 1.9 7.5 6.5 0.0 5.4 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EIW85223.1 - 0.0016 17.8 0.3 0.0091 15.3 0.0 2.4 3 0 0 3 3 3 1 CLASP N terminal OTU PF02338.14 EIW85224.1 - 1.9e-20 73.6 0.0 5.8e-20 72.0 0.0 1.7 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EIW85224.1 - 0.0031 16.8 0.0 1.5 8.0 0.0 2.3 1 1 1 2 2 2 2 Peptidase C65 Otubain Arm PF00514.18 EIW85225.1 - 0.56 10.1 8.1 59 3.6 0.0 6.4 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat ECH PF00378.15 EIW85226.1 - 4.2e-20 71.8 0.0 4.9e-20 71.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family AA_permease PF00324.16 EIW85227.1 - 4.3e-111 371.6 38.7 5.1e-111 371.3 26.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIW85227.1 - 1.5e-30 106.1 39.6 1.9e-30 105.7 27.5 1.1 1 0 0 1 1 1 1 Amino acid permease Pirin PF02678.11 EIW85229.1 - 8.3e-31 106.0 0.2 2.3e-30 104.6 0.1 1.7 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 EIW85229.1 - 6.5e-27 93.6 0.1 3e-26 91.5 0.0 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EIW85229.1 - 0.02 14.3 0.5 0.21 11.1 0.3 2.4 2 0 0 2 2 2 0 Cupin domain R3H PF01424.17 EIW85230.1 - 2.4e-05 23.9 0.0 4.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 EIW85230.1 - 0.0095 15.8 17.3 0.0095 15.8 12.0 13.0 12 0 0 12 12 12 6 NF-X1 type zinc finger CLTH PF10607.4 EIW85231.1 - 2.6e-23 82.3 0.0 5.1e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EIW85231.1 - 4.4e-17 61.5 0.7 9.9e-17 60.3 0.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.7 EIW85231.1 - 0.00059 19.1 0.0 0.00093 18.4 0.0 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.1 EIW85231.1 - 0.0057 16.4 0.1 0.011 15.5 0.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EIW85231.1 - 0.017 14.8 0.2 0.034 13.8 0.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIW85231.1 - 0.018 15.0 0.6 0.032 14.2 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EIW85231.1 - 0.02 14.4 0.9 0.04 13.4 0.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 EIW85231.1 - 0.027 14.1 0.6 0.053 13.1 0.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW85231.1 - 0.14 11.8 0.4 0.24 11.0 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 EIW85233.1 - 2.3e-25 88.0 0.0 2e-12 46.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PUF PF00806.14 EIW85233.1 - 3.6e-21 73.3 0.0 0.00012 21.3 0.0 5.8 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_6 PF14259.1 EIW85233.1 - 5.3e-17 61.5 0.0 4.4e-08 32.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW85233.1 - 1.3e-13 50.5 0.0 1e-06 28.4 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3517 PF12030.3 EIW85233.1 - 0.099 11.1 0.0 0.16 10.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3517) SHOCT PF09851.4 EIW85233.1 - 0.28 10.6 0.2 0.5 9.9 0.1 1.4 1 0 0 1 1 1 0 Short C-terminal domain Linker_histone PF00538.14 EIW85234.1 - 1.8e-13 50.4 0.7 5.1e-13 48.9 0.0 2.1 2 0 0 2 2 2 1 linker histone H1 and H5 family AMP-binding PF00501.23 EIW85235.1 - 8.9e-17 60.5 0.0 1.3e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Telomere_reg-2 PF10193.4 EIW85236.1 - 1.5e-24 86.4 0.0 3.6e-24 85.2 0.0 1.7 1 0 0 1 1 1 1 Telomere length regulation protein Pkinase PF00069.20 EIW85237.1 - 1.2e-61 208.1 0.0 1.7e-61 207.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW85237.1 - 1e-32 113.2 0.0 2e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW85237.1 - 0.0002 20.4 0.0 0.00032 19.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW85237.1 - 0.025 14.3 0.4 0.11 12.2 0.0 2.2 3 0 0 3 3 3 0 Phosphotransferase enzyme family 2Fe-2S_thioredx PF01257.14 EIW85238.1 - 5.6e-58 194.6 0.0 6.8e-58 194.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Bestrophin PF01062.16 EIW85239.1 - 3.9e-47 160.6 2.3 9.6e-27 93.6 0.1 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel S-AdoMet_synt_M PF02772.11 EIW85239.1 - 0.14 12.0 0.0 0.74 9.7 0.0 2.1 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, central domain TEA PF01285.13 EIW85240.1 - 2.2e-20 73.2 1.3 9.3e-20 71.1 0.9 2.0 1 1 0 1 1 1 1 TEA/ATTS domain family Pox_MCEL PF03291.11 EIW85242.1 - 6.4e-85 284.9 0.0 8.3e-85 284.5 0.0 1.1 1 0 0 1 1 1 1 mRNA capping enzyme Methyltransf_31 PF13847.1 EIW85242.1 - 1.9e-12 47.0 0.0 3e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW85242.1 - 7.1e-12 45.3 0.0 1e-11 44.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW85242.1 - 5.6e-11 42.7 0.0 9.6e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW85242.1 - 1.7e-10 41.2 0.0 3.1e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW85242.1 - 2.3e-10 41.0 0.0 3.9e-10 40.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW85242.1 - 1.9e-09 37.7 0.0 3.3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW85242.1 - 2.1e-05 24.4 0.0 4.6e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EIW85242.1 - 0.00038 19.4 0.0 0.00064 18.7 0.0 1.3 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family MTS PF05175.9 EIW85242.1 - 0.00072 18.9 0.0 0.0015 17.9 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain TPMT PF05724.6 EIW85242.1 - 0.015 14.7 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_4 PF02390.12 EIW85242.1 - 0.029 13.4 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_32 PF13679.1 EIW85242.1 - 0.19 11.4 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain O-FucT PF10250.4 EIW85243.1 - 8.3e-05 21.8 0.0 0.096 11.7 0.0 2.3 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase HECT PF00632.20 EIW85244.1 - 5.2e-90 301.8 0.0 7.6e-90 301.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EIW85244.1 - 2.4e-34 116.7 19.8 1.5e-11 43.9 4.1 3.5 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EIW85244.1 - 3.2e-16 58.9 0.2 8e-16 57.6 0.1 1.7 1 0 0 1 1 1 1 C2 domain PaREP1 PF05942.6 EIW85245.1 - 2.6e-05 24.0 0.0 2.6e-05 24.0 0.0 2.1 2 1 0 2 2 2 1 Archaeal PaREP1/PaREP8 family Orbi_VP5 PF00901.12 EIW85245.1 - 0.029 12.5 1.8 0.055 11.6 1.2 1.4 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 DUF3776 PF12618.3 EIW85245.1 - 0.077 13.5 0.3 0.077 13.5 0.2 3.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3776) DUF972 PF06156.8 EIW85245.1 - 0.17 12.2 11.3 0.15 12.3 1.7 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF972) WD40_alt PF14077.1 EIW85245.1 - 0.41 10.3 3.9 1.1 8.9 2.7 1.7 1 0 0 1 1 1 0 Alternative WD40 repeat motif DUF2383 PF09537.5 EIW85245.1 - 0.68 10.2 8.4 4.5 7.5 0.2 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) HALZ PF02183.13 EIW85245.1 - 2.5 7.8 5.6 8.5 6.1 0.2 2.9 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF904 PF06005.7 EIW85245.1 - 7.3 6.9 14.9 18 5.6 0.1 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF904) Mog1 PF04603.7 EIW85246.1 - 8.1e-31 106.8 0.0 9.8e-31 106.5 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein Ndc80_HEC PF03801.8 EIW85247.1 - 3.1e-32 111.2 0.0 6.4e-32 110.2 0.0 1.5 1 0 0 1 1 1 1 HEC/Ndc80p family EzrA PF06160.7 EIW85247.1 - 0.00049 18.4 13.3 0.0027 15.9 0.3 2.5 2 0 0 2 2 2 2 Septation ring formation regulator, EzrA Myosin_tail_1 PF01576.14 EIW85247.1 - 0.035 11.8 31.4 0.026 12.2 8.5 2.1 2 0 0 2 2 2 0 Myosin tail Fib_alpha PF08702.5 EIW85247.1 - 0.23 11.6 16.6 0.071 13.2 1.4 3.0 2 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Spc7 PF08317.6 EIW85247.1 - 0.23 10.0 22.4 0.12 11.0 3.3 2.6 2 1 0 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.3 EIW85247.1 - 3.9 7.3 28.8 2.2 8.1 3.3 3.7 2 2 1 3 3 3 0 Afadin- and alpha -actinin-Binding YoqO PF14037.1 EIW85248.1 - 0.03 14.4 1.1 0.062 13.4 0.8 1.4 1 0 0 1 1 1 0 YoqO-like protein DUF1469 PF07332.6 EIW85248.1 - 0.15 11.7 0.2 0.31 10.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) RNase_T PF00929.19 EIW85249.1 - 4.5e-12 46.5 0.0 6.9e-11 42.7 0.0 2.2 1 1 0 1 1 1 1 Exonuclease CMS1 PF14617.1 EIW85250.1 - 6.3e-76 254.7 1.6 7.3e-76 254.5 1.1 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit Rrn6 PF10214.4 EIW85250.1 - 0.032 12.3 3.0 0.045 11.8 2.1 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Nop14 PF04147.7 EIW85250.1 - 0.59 7.9 11.5 0.79 7.5 8.0 1.1 1 0 0 1 1 1 0 Nop14-like family L31 PF09784.4 EIW85251.1 - 4.8e-37 126.1 0.2 5.3e-37 126.0 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Pellino PF04710.9 EIW85251.1 - 0.073 11.7 0.1 0.086 11.4 0.1 1.0 1 0 0 1 1 1 0 Pellino PRP21_like_P PF12230.3 EIW85252.1 - 2.7e-59 200.4 8.2 2.7e-59 200.4 5.7 2.2 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EIW85252.1 - 1.9e-33 113.8 2.1 1e-15 57.0 0.1 2.7 3 0 0 3 3 3 2 Surp module ubiquitin PF00240.18 EIW85252.1 - 4.3e-10 38.8 0.0 7.9e-10 37.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EIW85252.1 - 0.0005 19.7 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EIW85252.1 - 0.13 12.4 0.0 0.13 12.4 0.0 2.8 4 0 0 4 4 4 0 DUF2407 ubiquitin-like domain NOA36 PF06524.7 EIW85252.1 - 4.7 6.3 7.5 0.91 8.7 2.4 1.8 2 0 0 2 2 2 0 NOA36 protein UQ_con PF00179.21 EIW85254.1 - 4.9e-22 77.8 0.0 6.7e-22 77.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF4658 PF15555.1 EIW85254.1 - 0.00076 19.3 0.8 0.0016 18.3 0.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4658) CcmH PF03918.9 EIW85254.1 - 0.009 15.0 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 Cytochrome C biogenesis protein RWD PF05773.17 EIW85254.1 - 0.026 14.4 0.0 0.045 13.6 0.0 1.5 1 1 0 1 1 1 0 RWD domain Rubredoxin PF00301.15 EIW85254.1 - 0.041 13.7 1.1 0.11 12.4 0.0 2.2 3 0 0 3 3 3 0 Rubredoxin CHCH PF06747.8 EIW85255.1 - 0.0054 16.6 0.4 0.0069 16.2 0.3 1.1 1 0 0 1 1 1 1 CHCH domain HTH_5 PF01022.15 EIW85255.1 - 0.05 13.2 0.1 1.8 8.2 0.0 2.1 2 0 0 2 2 2 0 Bacterial regulatory protein, arsR family DUF3128 PF11326.3 EIW85255.1 - 0.13 12.3 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3128) NYN PF01936.13 EIW85256.1 - 1.9e-26 93.0 0.0 4.7e-26 91.8 0.0 1.6 1 0 0 1 1 1 1 NYN domain Transcrip_reg PF01709.15 EIW85257.1 - 2.2e-60 203.7 0.0 2.5e-60 203.5 0.0 1.0 1 0 0 1 1 1 1 Transcriptional regulator Sulfate_transp PF00916.15 EIW85258.1 - 5.4e-77 258.5 6.2 8.9e-77 257.8 4.3 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EIW85258.1 - 4.1e-32 109.6 4.6 4.1e-32 109.6 3.2 3.4 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EIW85258.1 - 8.6e-10 38.0 0.0 1.6e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 STAS domain WD40 PF00400.27 EIW85259.1 - 3.5e-37 124.9 15.0 1.5e-13 49.9 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat adh_short_C2 PF13561.1 EIW85260.1 - 8.2e-24 84.6 0.0 1.1e-23 84.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIW85260.1 - 4.7e-23 81.9 1.4 8e-23 81.1 1.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW85260.1 - 3.1e-11 43.2 0.7 5.3e-11 42.5 0.5 1.3 1 0 0 1 1 1 1 KR domain PIN_4 PF13638.1 EIW85261.1 - 4.6e-23 81.7 0.0 1.5e-22 80.1 0.0 1.9 1 0 0 1 1 1 1 PIN domain EST1_DNA_bind PF10373.4 EIW85261.1 - 2.7e-16 59.6 0.0 1.2e-15 57.4 0.0 2.2 2 1 0 2 2 2 1 Est1 DNA/RNA binding domain RAP1 PF07218.6 EIW85261.1 - 0.48 8.4 4.0 0.73 7.8 2.8 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) NDK PF00334.14 EIW85262.1 - 2.8e-54 182.5 0.0 3.4e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Transketolase_N PF00456.16 EIW85263.1 - 7.4e-141 468.7 0.1 9.5e-141 468.4 0.1 1.1 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EIW85263.1 - 2.3e-44 151.0 0.1 7.1e-44 149.4 0.0 1.8 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EIW85263.1 - 2.6e-12 46.7 0.0 5.3e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DXP_synthase_N PF13292.1 EIW85263.1 - 2.8e-05 23.1 0.2 7.4e-05 21.8 0.0 1.7 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Terpene_synth PF01397.16 EIW85263.1 - 0.13 11.6 0.3 0.37 10.1 0.0 1.7 2 0 0 2 2 2 0 Terpene synthase, N-terminal domain Cmc1 PF08583.5 EIW85264.1 - 1.9e-11 43.5 3.9 1.9e-11 43.5 2.7 1.6 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like zinc-ribbons_6 PF07191.7 EIW85264.1 - 0.014 15.1 0.7 0.024 14.3 0.5 1.5 1 1 0 1 1 1 0 zinc-ribbons CHCH PF06747.8 EIW85264.1 - 0.69 9.9 3.0 1.3 8.9 0.2 2.2 2 0 0 2 2 2 0 CHCH domain OPT PF03169.10 EIW85265.1 - 3.4e-146 488.2 48.7 3.9e-146 488.0 33.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Peptidase_S9 PF00326.16 EIW85266.1 - 1.2e-37 129.2 0.1 2e-37 128.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIW85266.1 - 1.6e-13 50.6 0.1 4.4e-13 49.2 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW85266.1 - 3.1e-07 30.5 0.6 2.5e-06 27.5 0.4 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EIW85266.1 - 9.5e-06 25.0 0.0 1.7e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_4 PF08386.5 EIW85266.1 - 0.00017 21.4 0.1 0.0013 18.5 0.0 2.4 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 EIW85266.1 - 0.0002 21.0 0.0 0.00092 18.8 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.6 EIW85266.1 - 0.002 17.8 0.1 0.012 15.3 0.1 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 EIW85266.1 - 0.0023 17.5 0.1 0.0066 16.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 EIW85266.1 - 0.0083 15.5 0.0 0.015 14.7 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) PD40 PF07676.7 EIW85266.1 - 0.061 13.0 4.4 1.5 8.5 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat AXE1 PF05448.7 EIW85266.1 - 0.098 11.1 1.9 1.2 7.5 0.1 2.9 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_2 PF02230.11 EIW85266.1 - 0.11 11.9 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DNA_pol_E_B PF04042.11 EIW85267.1 - 6.7e-35 120.2 0.1 1.3e-16 60.5 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase alpha/epsilon subunit B Rubella_Capsid PF05750.6 EIW85267.1 - 0.079 12.3 0.4 0.14 11.5 0.3 1.3 1 0 0 1 1 1 0 Rubella capsid protein Pyridoxal_deC PF00282.14 EIW85268.1 - 6e-59 199.3 0.0 9.3e-59 198.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EIW85268.1 - 2.2e-05 23.3 0.0 3.5e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V PALP PF00291.20 EIW85269.1 - 2e-53 181.6 0.0 2.7e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme AlaDh_PNT_C PF01262.16 EIW85269.1 - 0.00078 19.0 0.1 0.0017 17.9 0.0 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 EIW85269.1 - 0.054 12.3 0.2 0.083 11.7 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Fimbrillin_C PF15495.1 EIW85269.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Major fimbrial subunit protein type IV, Fimbrillin, C-terminal Glyco_hydro_31 PF01055.21 EIW85270.1 - 4.8e-124 414.5 0.6 7e-124 414.0 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EIW85270.1 - 1.6e-17 63.0 0.4 7.1e-17 61.0 0.1 2.1 2 0 0 2 2 2 1 Galactose mutarotase-like Hid1 PF12722.2 EIW85271.1 - 4.2e-148 494.6 0.0 1.1e-147 493.2 0.0 1.5 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EIW85271.1 - 2.2e-66 224.3 0.1 3.1e-66 223.8 0.0 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Rad51 PF08423.6 EIW85272.1 - 7.4e-05 21.7 0.0 0.0001 21.2 0.0 1.1 1 0 0 1 1 1 1 Rad51 Isochorismatase PF00857.15 EIW85272.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Isochorismatase family Atg8 PF02991.11 EIW85273.1 - 3.2e-52 174.8 0.2 3.8e-52 174.5 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EIW85273.1 - 3e-07 30.5 0.0 3.6e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 SH3_2 PF07653.12 EIW85273.1 - 0.09 12.2 0.0 0.21 11.1 0.0 1.6 1 1 0 1 1 1 0 Variant SH3 domain Band_7 PF01145.20 EIW85274.1 - 9.8e-06 25.5 9.8 2.1e-05 24.5 4.5 2.7 2 1 0 2 2 2 1 SPFH domain / Band 7 family Glyco_hydro_63 PF03200.11 EIW85275.1 - 5.1e-230 765.4 0.0 4.3e-229 762.4 0.0 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EIW85275.1 - 0.00088 18.0 0.0 0.0015 17.2 0.0 1.2 1 0 0 1 1 1 1 Trehalase Lactamase_B_2 PF12706.2 EIW85277.1 - 3.4e-14 52.8 0.0 4.3e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Pkinase PF00069.20 EIW85278.1 - 1.8e-60 204.2 0.0 2.1e-60 204.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW85278.1 - 2e-24 86.0 0.0 2.6e-24 85.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW85278.1 - 1.2e-05 24.3 0.0 3e-05 23.1 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIW85278.1 - 0.002 17.9 0.1 0.025 14.3 0.0 2.3 2 1 1 3 3 3 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIW85278.1 - 0.0045 16.5 0.0 0.0062 16.1 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase WD40 PF00400.27 EIW85279.1 - 6.8e-62 203.2 21.3 3.9e-10 39.1 0.0 8.7 8 1 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EIW85279.1 - 7.6e-13 47.9 0.8 1.9e-12 46.7 0.5 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW85279.1 - 2.5e-11 42.9 0.3 8e-11 41.3 0.2 2.0 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EIW85279.1 - 5.6e-08 31.3 11.1 0.44 8.6 0.0 6.2 2 2 2 5 5 5 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EIW85279.1 - 0.0015 18.2 0.1 4.4 7.1 0.0 4.5 4 2 1 5 5 5 1 Ciliary BBSome complex subunit 2, middle region LigB PF02900.13 EIW85280.1 - 1.1e-35 122.9 0.0 2.5e-35 121.7 0.0 1.5 1 1 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase PHP PF02811.14 EIW85280.1 - 0.051 13.3 0.0 0.89 9.3 0.0 2.1 2 0 0 2 2 2 0 PHP domain COQ7 PF03232.8 EIW85282.1 - 1e-65 220.4 1.3 1e-65 220.4 0.9 1.3 2 0 0 2 2 2 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 EIW85282.1 - 0.00015 22.1 0.2 0.00053 20.3 0.1 1.9 1 1 1 2 2 2 1 Rubrerythrin DUF3849 PF12960.2 EIW85282.1 - 0.074 12.9 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3849) AOX PF01786.12 EIW85282.1 - 0.43 9.9 7.1 1.7 7.9 0.5 2.5 1 1 0 2 2 2 0 Alternative oxidase NDUF_B4 PF07225.7 EIW85283.1 - 1.1e-06 28.4 0.1 1.3e-06 28.2 0.1 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Glyco_hydro_49 PF03718.8 EIW85283.1 - 0.091 10.8 0.1 0.091 10.8 0.0 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 49 G-patch PF01585.18 EIW85284.1 - 1e-11 44.4 1.7 2.2e-11 43.3 1.2 1.6 1 0 0 1 1 1 1 G-patch domain RRM_6 PF14259.1 EIW85284.1 - 5.8e-07 29.4 0.0 0.0028 17.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 EIW85284.1 - 2.4e-05 24.0 1.3 2.4e-05 24.0 0.9 2.7 2 0 0 2 2 2 1 DExH-box splicing factor binding site RRM_1 PF00076.17 EIW85284.1 - 3.3e-05 23.4 1.9 0.025 14.1 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_jaz PF12171.3 EIW85284.1 - 0.0032 17.5 0.1 0.0063 16.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding RRM_5 PF13893.1 EIW85284.1 - 0.0071 16.1 0.2 1.6 8.6 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_2 PF12756.2 EIW85284.1 - 0.077 13.1 0.3 0.15 12.2 0.2 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EIW85284.1 - 0.77 10.2 3.9 0.37 11.2 0.3 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger CAP_N PF01213.14 EIW85284.1 - 4.9 6.3 16.7 1.2 8.3 0.6 2.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal FH2 PF02181.18 EIW85285.1 - 1.6e-77 260.9 3.4 1.6e-77 260.9 2.4 2.4 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EIW85285.1 - 1.4e-31 109.3 0.0 1.4e-31 109.3 0.0 2.8 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EIW85285.1 - 2.4e-30 105.4 1.7 4.4e-30 104.5 0.0 2.3 2 0 0 2 2 2 1 Diaphanous FH3 Domain DUF972 PF06156.8 EIW85285.1 - 1 9.7 9.7 0.73 10.2 0.3 4.9 3 1 1 4 4 4 0 Protein of unknown function (DUF972) FUSC_2 PF13515.1 EIW85286.1 - 2.2e-14 53.4 13.1 2.2e-14 53.4 9.1 3.2 2 1 1 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.7 EIW85286.1 - 4.6e-11 41.8 1.5 4.6e-11 41.8 1.0 3.0 3 0 0 3 3 3 2 Fusaric acid resistance protein family DUF2422 PF10337.4 EIW85286.1 - 1.5e-07 30.6 7.6 0.00075 18.3 0.1 3.4 2 1 1 3 3 3 3 Protein of unknown function (DUF2422) DUF2421 PF10334.4 EIW85286.1 - 1.7e-05 24.5 0.4 5.4e-05 22.9 0.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2421) ALMT PF11744.3 EIW85286.1 - 0.00026 19.7 8.6 0.00026 19.7 6.0 3.2 4 0 0 4 4 4 1 Aluminium activated malate transporter DUF939 PF06081.6 EIW85286.1 - 0.3 10.9 12.8 0.022 14.6 3.7 2.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF939) Myosin_head PF00063.16 EIW85287.1 - 1e-236 787.2 0.0 3.2e-236 785.6 0.0 1.7 2 0 0 2 2 2 1 Myosin head (motor domain) DIL PF01843.14 EIW85287.1 - 1.4e-33 114.9 1.8 1.4e-33 114.9 1.2 2.9 3 0 0 3 3 3 1 DIL domain IQ PF00612.22 EIW85287.1 - 1e-12 46.4 40.2 0.02 14.4 0.9 7.1 7 0 0 7 7 7 6 IQ calmodulin-binding motif AAA_22 PF13401.1 EIW85287.1 - 0.015 15.4 1.4 0.076 13.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain IncA PF04156.9 EIW85287.1 - 0.2 11.1 24.4 0.55 9.7 16.9 1.7 1 0 0 1 1 1 0 IncA protein Phlebovirus_NSM PF07246.6 EIW85287.1 - 1.1 8.3 10.0 2.3 7.3 6.9 1.5 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M SlyX PF04102.7 EIW85287.1 - 2.5 8.5 18.7 0.37 11.1 3.1 4.0 2 1 1 3 3 3 0 SlyX APG6 PF04111.7 EIW85287.1 - 2.8 6.8 20.6 5.8 5.8 14.3 1.5 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-AN1 PF01428.11 EIW85288.1 - 8.2e-15 54.3 17.6 1.2e-09 37.8 3.6 2.6 3 0 0 3 3 3 2 AN1-like Zinc finger COG4 PF08318.7 EIW85289.1 - 2.3e-56 190.9 0.0 3.2e-56 190.4 0.0 1.2 1 0 0 1 1 1 1 COG4 transport protein MutS_III PF05192.13 EIW85289.1 - 0.017 14.9 4.5 0.13 12.0 3.1 2.7 1 1 0 1 1 1 0 MutS domain III Reo_sigmaC PF04582.7 EIW85289.1 - 0.086 12.0 6.5 0.097 11.8 2.0 2.3 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EIW85289.1 - 0.42 10.4 4.5 1.8 8.4 2.1 2.7 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glyco_hydro_3 PF00933.16 EIW85290.1 - 5.1e-75 252.2 0.0 8.2e-75 251.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIW85290.1 - 2.5e-68 230.0 0.0 2.8e-67 226.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIW85290.1 - 5e-24 84.0 0.0 1.2e-23 82.8 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EIW85290.1 - 1e-10 41.4 0.1 2e-10 40.5 0.1 1.4 1 0 0 1 1 1 1 PA14 domain PIG-S PF10510.4 EIW85290.1 - 0.36 9.4 0.0 0.53 8.8 0.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein DUF2340 PF10209.4 EIW85291.1 - 3.8e-47 159.4 2.0 4.4e-47 159.2 1.4 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) DnaJ PF00226.26 EIW85292.1 - 6.5e-23 80.2 1.8 1.4e-22 79.1 1.3 1.6 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EIW85292.1 - 1.2e-20 73.1 1.8 2.2e-18 65.9 0.0 2.9 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EIW85292.1 - 1.1e-13 51.0 18.9 1.9e-13 50.2 13.1 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EIW85292.1 - 0.035 13.8 9.5 0.35 10.5 1.4 2.3 1 1 0 2 2 2 0 Hydrogenase expression/synthesis hypA family CN_hydrolase PF00795.17 EIW85293.1 - 6.9e-30 103.7 0.0 9.1e-30 103.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DAGK_cat PF00781.19 EIW85294.1 - 1.3e-14 53.7 0.0 2.2e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain ADK PF00406.17 EIW85295.1 - 1.8e-44 151.2 0.0 3.1e-44 150.4 0.0 1.3 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EIW85295.1 - 2.5e-10 40.7 0.0 3.4e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW85295.1 - 3.7e-07 30.9 0.0 5.8e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW85295.1 - 7.2e-05 22.6 0.0 0.00015 21.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EIW85295.1 - 0.0055 16.0 0.0 0.035 13.4 0.0 2.0 1 1 0 1 1 1 1 Thymidylate kinase AAA PF00004.24 EIW85295.1 - 0.085 13.0 0.0 0.13 12.4 0.0 1.5 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) WD40 PF00400.27 EIW85296.1 - 1.3e-05 24.8 1.8 0.0015 18.3 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Fungal_trans PF04082.13 EIW85297.1 - 7e-22 77.5 0.2 1.5e-21 76.4 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW85297.1 - 0.077 12.9 3.6 0.15 12.0 2.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain P_C PF06640.6 EIW85297.1 - 2.1 8.3 6.6 0.31 10.9 0.9 1.9 1 1 1 2 2 2 0 P protein C-terminus OB_NTP_bind PF07717.11 EIW85298.1 - 5.2e-20 71.3 0.0 1.1e-19 70.2 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EIW85298.1 - 1.7e-18 66.5 0.0 3e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EIW85298.1 - 3.1e-11 42.9 0.0 5.8e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIW85298.1 - 0.058 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase M3 PF09213.5 EIW85298.1 - 0.18 10.2 0.0 0.3 9.5 0.0 1.3 1 0 0 1 1 1 0 M3 Mis14 PF08641.7 EIW85299.1 - 0.00052 20.0 4.6 0.00087 19.3 3.2 1.4 1 0 0 1 1 1 1 Kinetochore protein Mis14 like Gar1 PF04410.9 EIW85300.1 - 6.5e-42 142.6 2.2 1.1e-41 141.8 0.0 1.9 1 1 1 2 2 2 1 Gar1/Naf1 RNA binding region AAA PF00004.24 EIW85301.1 - 5.7e-60 201.2 0.0 6.4e-45 152.5 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIW85301.1 - 7.7e-07 29.9 0.0 0.0049 17.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EIW85301.1 - 1.5e-06 27.9 0.0 0.0095 15.6 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIW85301.1 - 2.3e-06 27.7 3.5 0.072 13.0 0.1 4.2 3 1 1 4 4 4 2 AAA ATPase domain AAA_14 PF13173.1 EIW85301.1 - 5.6e-06 26.2 0.0 0.065 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EIW85301.1 - 0.00013 21.1 0.0 0.0066 15.5 0.0 2.8 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EIW85301.1 - 0.0002 20.8 0.9 0.073 12.4 0.2 2.5 1 1 1 2 2 2 1 AAA domain AAA_22 PF13401.1 EIW85301.1 - 0.0002 21.4 0.1 0.0047 17.0 0.0 3.1 3 1 0 3 3 1 1 AAA domain DUF815 PF05673.8 EIW85301.1 - 0.00044 19.2 0.0 0.68 8.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_19 PF13245.1 EIW85301.1 - 0.00049 19.7 0.0 0.0034 17.0 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_3 PF07726.6 EIW85301.1 - 0.00052 19.6 0.0 0.4 10.2 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.12 EIW85301.1 - 0.00062 19.2 0.0 0.0014 18.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein KaiC PF06745.8 EIW85301.1 - 0.00081 18.5 0.0 0.0018 17.4 0.0 1.5 1 0 0 1 1 1 1 KaiC AAA_2 PF07724.9 EIW85301.1 - 0.00084 19.2 0.0 0.0031 17.4 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.8 EIW85301.1 - 0.0017 17.1 0.0 0.034 12.8 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus AAA_18 PF13238.1 EIW85301.1 - 0.002 18.4 0.0 0.11 12.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EIW85301.1 - 0.0044 16.2 0.1 0.023 13.8 0.1 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EIW85301.1 - 0.006 16.4 0.0 0.065 13.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIW85301.1 - 0.0071 16.5 0.0 0.15 12.2 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 EIW85301.1 - 0.0072 16.2 0.0 0.054 13.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain Parvo_NS1 PF01057.12 EIW85301.1 - 0.027 13.3 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 PhoH PF02562.11 EIW85301.1 - 0.03 13.5 0.1 0.055 12.7 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein Rad51 PF08423.6 EIW85301.1 - 0.032 13.1 0.0 0.057 12.3 0.0 1.3 1 0 0 1 1 1 0 Rad51 NACHT PF05729.7 EIW85301.1 - 0.047 13.3 0.5 3.2 7.3 0.1 3.1 3 0 0 3 3 3 0 NACHT domain UPF0079 PF02367.12 EIW85301.1 - 0.053 13.1 0.1 1 8.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activat PF00158.21 EIW85301.1 - 0.059 12.8 0.1 1.6 8.1 0.0 2.6 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_24 PF13479.1 EIW85301.1 - 0.076 12.5 0.2 0.16 11.5 0.2 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EIW85301.1 - 0.096 12.3 0.1 2.5 7.7 0.0 2.4 2 0 0 2 2 2 0 NTPase Sigma54_activ_2 PF14532.1 EIW85301.1 - 0.11 12.5 0.1 2 8.4 0.0 2.9 3 0 0 3 3 3 0 Sigma-54 interaction domain HSNSD PF12062.3 EIW85301.1 - 0.23 9.8 0.0 0.36 9.1 0.0 1.2 1 0 0 1 1 1 0 heparan sulfate-N-deacetylase Dimer_Tnp_hAT PF05699.9 EIW85302.1 - 2.7e-07 30.1 0.0 2.7e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pkinase PF00069.20 EIW85309.1 - 6.9e-40 136.8 0.1 7e-27 94.2 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW85309.1 - 6.9e-22 77.7 0.1 1.3e-12 47.3 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase FHA PF00498.21 EIW85309.1 - 7.6e-08 32.3 0.1 2e-07 31.0 0.1 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EIW85309.1 - 0.059 12.3 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like UBN2_3 PF14244.1 EIW85311.1 - 6.2e-05 22.5 0.0 7.5e-05 22.3 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EIW85311.1 - 0.093 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type EF-hand_8 PF13833.1 EIW85313.1 - 0.047 13.3 0.5 0.2 11.2 0.1 2.1 2 0 0 2 2 2 0 EF-hand domain pair Alpha_kinase PF02816.13 EIW85314.1 - 1.7e-06 27.8 0.0 5.6e-06 26.1 0.0 1.7 2 0 0 2 2 2 1 Alpha-kinase family MecA PF05389.7 EIW85317.1 - 0.022 14.2 0.0 0.046 13.2 0.0 1.4 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) DUF4475 PF14753.1 EIW85322.1 - 0.037 13.5 0.6 0.042 13.3 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4475) UPF0203 PF05254.7 EIW85322.1 - 0.081 12.7 0.2 0.11 12.4 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0203) DCP2 PF05026.8 EIW85322.1 - 0.091 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Dcp2, box A domain PNK3P PF08645.6 EIW85323.1 - 1.6e-46 157.6 0.0 3e-46 156.7 0.0 1.4 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EIW85323.1 - 2.8e-24 85.6 0.0 7.9e-23 80.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EIW85323.1 - 0.0018 17.4 0.0 0.034 13.2 0.0 2.1 1 1 1 2 2 2 1 Zeta toxin HAD_2 PF13419.1 EIW85323.1 - 0.0049 17.1 0.1 0.17 12.1 0.0 2.9 3 1 1 4 4 4 1 Haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EIW85323.1 - 0.015 15.1 0.0 0.44 10.4 0.0 2.4 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase AAA_17 PF13207.1 EIW85323.1 - 0.019 15.7 0.0 0.18 12.6 0.0 2.5 2 1 0 2 2 2 0 AAA domain LNS2 PF08235.8 EIW85323.1 - 0.035 13.6 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) Acid_phosphat_B PF03767.9 EIW85323.1 - 0.079 12.3 0.1 0.69 9.2 0.0 2.3 2 1 0 2 2 2 0 HAD superfamily, subfamily IIIB (Acid phosphatase) KTI12 PF08433.5 EIW85323.1 - 0.31 10.1 1.0 2.5 7.2 0.4 2.5 2 1 0 2 2 2 0 Chromatin associated protein KTI12 PITH PF06201.8 EIW85324.1 - 8.2e-42 142.5 0.5 9.4e-42 142.3 0.3 1.0 1 0 0 1 1 1 1 PITH domain Sad1_UNC PF07738.8 EIW85324.1 - 0.00038 20.2 0.1 0.001 18.8 0.1 1.7 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal Sel1 PF08238.7 EIW85325.1 - 7.5e-46 153.5 30.1 1.3e-07 32.0 0.0 7.8 8 0 0 8 8 8 7 Sel1 repeat TPR_14 PF13428.1 EIW85325.1 - 0.025 15.1 0.8 0.025 15.1 0.5 5.8 6 2 1 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 EIW85325.1 - 0.38 11.3 0.1 0.38 11.3 0.1 5.3 5 1 0 5 5 5 0 Tetratricopeptide repeat JmjC PF02373.17 EIW85326.1 - 3.4e-08 33.7 1.1 1.6e-07 31.5 0.8 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.24 EIW85326.1 - 1.3e-07 31.1 7.7 2.4e-07 30.3 5.4 1.5 1 0 0 1 1 1 1 PHD-finger Cupin_8 PF13621.1 EIW85326.1 - 2.1e-06 27.4 0.2 7.2e-06 25.6 0.2 1.7 1 1 0 1 1 1 1 Cupin-like domain PHD_2 PF13831.1 EIW85326.1 - 0.0061 15.8 5.4 0.013 14.8 3.7 1.5 1 0 0 1 1 1 1 PHD-finger Cupin_4 PF08007.7 EIW85326.1 - 0.036 13.3 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein GPI PF06560.6 EIW85326.1 - 0.076 12.0 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Prok-RING_1 PF14446.1 EIW85326.1 - 0.3 10.8 7.6 0.26 11.0 4.1 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Lamp PF01299.12 EIW85326.1 - 6.3 5.8 5.9 9.1 5.3 4.1 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) PGK PF00162.14 EIW85327.1 - 1.2e-147 491.4 0.1 1.4e-147 491.2 0.1 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase PrpR_N PF06506.6 EIW85327.1 - 0.12 11.7 0.4 0.33 10.3 0.1 1.8 2 0 0 2 2 2 0 Propionate catabolism activator IncA PF04156.9 EIW85328.1 - 2.7 7.5 7.0 3 7.3 4.8 1.1 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EIW85328.1 - 4.9 6.1 10.8 6.7 5.6 7.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 SDA1 PF05285.7 EIW85329.1 - 1.2e-74 251.5 37.0 7.7e-39 133.8 7.9 3.1 2 1 1 3 3 3 3 SDA1 NUC130_3NT PF08158.7 EIW85329.1 - 1.9e-21 76.0 0.4 1.2e-20 73.5 0.1 2.4 2 0 0 2 2 2 1 NUC130/3NT domain NUDIX PF00293.23 EIW85330.1 - 8e-12 44.9 0.0 2.4e-11 43.3 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain GalP_UDP_transf PF01087.17 EIW85331.1 - 5.6e-62 209.0 0.0 1.8e-61 207.4 0.0 1.8 2 0 0 2 2 2 1 Galactose-1-phosphate uridyl transferase, N-terminal domain GalP_UDP_tr_C PF02744.12 EIW85331.1 - 7.3e-45 152.4 0.1 1.2e-44 151.8 0.1 1.3 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain HIT PF01230.18 EIW85331.1 - 0.0049 17.3 1.3 0.02 15.4 0.2 2.4 2 1 0 2 2 2 1 HIT domain DcpS_C PF11969.3 EIW85331.1 - 0.28 11.4 2.9 2.2 8.5 1.3 2.8 2 1 0 2 2 2 0 Scavenger mRNA decapping enzyme C-term binding DEAD PF00270.24 EIW85332.1 - 6.4e-42 142.9 0.0 5.4e-41 139.8 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW85332.1 - 1.8e-23 82.1 0.0 2.5e-22 78.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EIW85332.1 - 0.0039 17.1 0.1 0.013 15.4 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.10 EIW85332.1 - 0.022 14.5 0.0 1.3 8.8 0.0 2.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit NTP_transf_4 PF13562.1 EIW85332.1 - 0.091 12.4 0.8 0.19 11.3 0.6 1.5 1 0 0 1 1 1 0 Sugar nucleotidyl transferase DUF1253 PF06862.7 EIW85332.1 - 0.11 10.9 0.0 0.11 10.9 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1253) zf-CCHC PF00098.18 EIW85332.1 - 0.49 10.4 1.6 0.93 9.5 1.1 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF1068 PF06364.7 EIW85332.1 - 6.7 6.2 9.5 11 5.5 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) HEAT_2 PF13646.1 EIW85333.1 - 1.7e-12 47.4 20.1 0.0019 18.4 0.8 8.9 7 2 1 8 8 8 5 HEAT repeats HEAT PF02985.17 EIW85333.1 - 3.6e-09 35.9 20.2 0.068 13.2 0.0 10.3 11 0 0 11 11 11 3 HEAT repeat Adaptin_N PF01602.15 EIW85333.1 - 2.9e-07 29.1 7.5 0.0031 15.8 3.2 3.4 2 1 0 2 2 2 2 Adaptin N terminal region HEAT_EZ PF13513.1 EIW85333.1 - 6.5e-06 26.4 27.1 0.0054 17.1 0.1 9.0 11 0 0 11 11 11 3 HEAT-like repeat Arm PF00514.18 EIW85333.1 - 1.7e-05 24.4 0.6 0.032 14.0 0.0 3.4 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.4 EIW85333.1 - 0.0032 15.7 0.7 0.01 14.1 0.1 2.1 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit DUF3454 PF11936.3 EIW85333.1 - 0.21 11.8 1.9 6.5 7.0 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3454) ARL2_Bind_BART PF11527.3 EIW85333.1 - 0.37 10.5 0.7 0.89 9.3 0.1 1.9 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART Rft-1 PF04506.8 EIW85334.1 - 3.4e-85 286.4 8.3 4.2e-85 286.1 5.7 1.1 1 0 0 1 1 1 1 Rft protein Fasciclin PF02469.17 EIW85335.1 - 2.8e-29 101.7 0.0 1.1e-17 64.1 0.0 3.8 3 1 0 3 3 3 2 Fasciclin domain ATP-synt_ab PF00006.20 EIW85336.1 - 3.9e-112 372.9 0.0 6.9e-112 372.1 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EIW85336.1 - 4e-21 75.6 3.5 8.5e-21 74.5 2.4 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EIW85336.1 - 5.1e-14 52.2 4.3 1.5e-13 50.7 3.0 1.9 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.24 EIW85337.1 - 1e-40 138.9 0.0 3.2e-40 137.3 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) BCDHK_Adom3 PF10436.4 EIW85337.1 - 3.5e-36 124.1 0.0 6.3e-36 123.3 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EIW85337.1 - 5.2e-14 51.9 0.1 9.9e-08 31.6 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_5 PF07728.9 EIW85337.1 - 3.3e-05 23.6 0.0 0.00025 20.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EIW85337.1 - 4.9e-05 23.4 0.0 0.0024 18.0 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EIW85337.1 - 0.00059 19.7 0.0 0.0016 18.3 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EIW85337.1 - 0.00066 19.7 0.0 0.0061 16.5 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain HATPase_c_3 PF13589.1 EIW85337.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF815 PF05673.8 EIW85337.1 - 0.0024 16.8 0.0 0.0045 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EIW85337.1 - 0.0074 17.1 0.1 0.019 15.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW85337.1 - 0.0098 15.6 0.1 0.027 14.2 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain Sigma54_activ_2 PF14532.1 EIW85337.1 - 0.013 15.5 0.0 0.082 12.9 0.0 2.2 2 1 0 2 2 2 0 Sigma-54 interaction domain DUF1845 PF08900.6 EIW85337.1 - 0.017 14.3 0.1 2 7.6 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1845) AAA_33 PF13671.1 EIW85337.1 - 0.019 14.8 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIW85337.1 - 0.019 14.0 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin RuvB_N PF05496.7 EIW85337.1 - 0.02 13.9 0.0 0.035 13.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EIW85337.1 - 0.02 14.8 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EIW85337.1 - 0.046 13.1 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_3 PF07726.6 EIW85337.1 - 0.063 12.8 0.0 0.18 11.4 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EIW85337.1 - 0.092 13.0 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EIW85337.1 - 0.11 11.2 0.0 0.19 10.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_14 PF13173.1 EIW85337.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.20 EIW85338.1 - 1.5e-55 188.1 0.0 2.5e-55 187.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW85338.1 - 1.9e-19 69.7 0.1 3.2e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW85338.1 - 0.0042 16.8 0.0 0.0086 15.8 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EIW85338.1 - 0.059 12.7 0.3 0.12 11.7 0.2 1.5 1 0 0 1 1 1 0 RIO1 family DUF4532 PF15046.1 EIW85339.1 - 0.0014 17.6 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4532) Zn_clus PF00172.13 EIW85340.1 - 0.00074 19.3 16.6 0.001 18.8 11.5 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 EIW85340.1 - 0.65 8.1 10.4 0.64 8.1 7.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_L18e PF00828.14 EIW85341.1 - 1.7e-20 73.7 0.0 3.1e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 PHD PF00628.24 EIW85342.1 - 6.1e-16 57.8 13.3 3.6e-10 39.3 2.9 2.4 2 0 0 2 2 2 2 PHD-finger Transferase PF02458.10 EIW85342.1 - 4.9e-09 35.1 0.0 9.4e-09 34.1 0.0 1.4 1 0 0 1 1 1 1 Transferase family C1_1 PF00130.17 EIW85342.1 - 0.00043 19.9 0.3 0.12 12.1 0.0 2.6 2 1 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-PHD-like PF15446.1 EIW85342.1 - 0.012 14.9 2.1 0.19 10.9 0.3 2.5 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PHD_2 PF13831.1 EIW85342.1 - 0.029 13.6 9.2 0.15 11.3 0.3 3.0 2 1 0 2 2 2 0 PHD-finger zf-HC5HC2H PF13771.1 EIW85342.1 - 0.33 11.1 4.9 0.05 13.7 0.4 1.9 2 0 0 2 2 2 0 PHD-like zinc-binding domain Prok-RING_1 PF14446.1 EIW85342.1 - 1.8 8.3 8.8 5.3 6.8 1.3 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 EIW85342.1 - 6.6 6.8 11.8 1.9 8.5 0.2 2.9 3 0 0 3 3 3 0 RING-like domain IPPT PF01715.12 EIW85343.1 - 4e-48 163.6 0.2 2.5e-25 88.9 0.0 2.6 1 1 1 2 2 2 2 IPP transferase AAA_17 PF13207.1 EIW85343.1 - 3.5e-05 24.6 0.0 0.00013 22.7 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIW85343.1 - 5.6e-05 23.4 0.4 0.0038 17.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIW85343.1 - 0.021 14.9 0.1 0.11 12.7 0.0 2.1 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.1 EIW85343.1 - 0.052 13.6 0.2 0.25 11.5 0.1 2.3 1 1 0 1 1 1 0 AAA domain IPT PF01745.11 EIW85343.1 - 0.1 11.7 0.0 0.21 10.7 0.0 1.5 1 0 0 1 1 1 0 Isopentenyl transferase AAA_10 PF12846.2 EIW85343.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain AMP-binding PF00501.23 EIW85344.1 - 5.2e-72 242.5 0.0 6.4e-72 242.2 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIW85344.1 - 8.3e-09 36.2 0.1 2.3e-08 34.8 0.0 1.9 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain PGM_PMM_I PF02878.11 EIW85345.1 - 8e-38 129.0 0.0 1.3e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EIW85345.1 - 2e-20 73.0 0.0 4.4e-20 71.9 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EIW85345.1 - 5.2e-18 65.1 0.1 1.8e-17 63.4 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EIW85345.1 - 4e-05 23.5 0.0 0.00021 21.2 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Phytochelatin PF05023.9 EIW85345.1 - 0.028 13.3 0.0 0.054 12.4 0.0 1.4 1 0 0 1 1 1 0 Phytochelatin synthase CDC50 PF03381.10 EIW85346.1 - 1e-88 297.1 0.3 1e-88 297.1 0.2 1.4 2 0 0 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF1138 PF06592.8 EIW85346.1 - 0.0062 16.5 0.1 0.027 14.4 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1138) RTC PF01137.16 EIW85347.1 - 2.5e-68 229.2 0.1 2.9e-68 229.0 0.1 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EIW85347.1 - 2.7e-20 72.3 0.2 4.9e-20 71.4 0.1 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain HOOK PF05622.7 EIW85348.1 - 2.8e-37 127.9 68.1 2.8e-37 127.9 47.2 2.8 1 1 1 2 2 2 1 HOOK protein NYD-SP28_assoc PF14775.1 EIW85348.1 - 0.0014 18.3 2.3 0.0014 18.3 1.6 4.9 6 0 0 6 6 6 1 Sperm tail C-terminal domain bZIP_1 PF00170.16 EIW85348.1 - 0.0024 17.8 2.4 0.0024 17.8 1.7 9.0 10 1 2 12 12 12 1 bZIP transcription factor Reo_sigmaC PF04582.7 EIW85348.1 - 5 6.2 33.5 0.087 11.9 0.6 5.0 3 1 2 5 5 5 0 Reovirus sigma C capsid protein Sugar_tr PF00083.19 EIW85349.1 - 2.8e-76 256.9 14.8 3.6e-76 256.5 10.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW85349.1 - 2.3e-17 62.7 23.4 4.4e-13 48.6 4.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIW85349.1 - 3.4e-06 25.7 25.1 0.0017 16.8 4.9 3.7 2 2 1 3 3 3 3 MFS/sugar transport protein Not1 PF04054.10 EIW85351.1 - 1.2e-118 396.3 0.1 2.1e-118 395.4 0.0 1.4 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EIW85351.1 - 4.6e-53 178.8 0.3 9.5e-53 177.8 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) FdhE PF04216.7 EIW85351.1 - 0.097 12.3 0.5 0.32 10.6 0.0 2.1 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation Pribosyltran PF00156.22 EIW85351.1 - 0.17 11.6 0.1 0.82 9.4 0.0 2.2 2 0 0 2 2 2 0 Phosphoribosyl transferase domain MRP-L46 PF11788.3 EIW85352.1 - 2.8e-18 66.5 0.8 5.5e-18 65.6 0.6 1.6 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EIW85352.1 - 7.7e-05 22.3 0.0 0.00015 21.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Ada_Zn_binding PF02805.11 EIW85352.1 - 0.06 12.9 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 Metal binding domain of Ada Endonuclease_NS PF01223.18 EIW85353.1 - 6e-52 176.2 0.0 7.4e-52 175.9 0.0 1.0 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease R3H PF01424.17 EIW85354.1 - 1.6e-12 46.9 0.0 4.2e-12 45.5 0.0 1.8 1 0 0 1 1 1 1 R3H domain RRM_1 PF00076.17 EIW85354.1 - 5.7e-07 29.0 0.0 1.3e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW85354.1 - 9e-07 28.7 0.0 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW85354.1 - 0.00067 19.4 0.1 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EcsC PF12787.2 EIW85354.1 - 0.097 12.0 0.1 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 EcsC protein family P33MONOX PF15302.1 EIW85355.1 - 0.072 12.6 0.2 0.091 12.3 0.2 1.1 1 0 0 1 1 1 0 P33 mono-oxygenase UQ_con PF00179.21 EIW85356.1 - 1.3e-46 157.4 0.0 1.6e-46 157.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EIW85356.1 - 0.00042 20.1 0.0 0.00056 19.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain EF-hand_4 PF12763.2 EIW85357.1 - 1.5e-35 121.0 0.0 1.2e-13 50.6 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand UBA PF00627.26 EIW85357.1 - 1.9e-09 37.0 0.1 4e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain EF-hand_7 PF13499.1 EIW85357.1 - 6.6e-09 35.7 0.0 5.7e-05 23.1 0.1 3.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EIW85357.1 - 2.2e-05 23.4 1.8 0.43 9.9 0.0 4.3 5 0 0 5 5 5 2 EF hand UBA_4 PF14555.1 EIW85357.1 - 0.017 14.6 0.1 0.038 13.5 0.1 1.5 1 0 0 1 1 1 0 UBA-like domain EF-hand_8 PF13833.1 EIW85357.1 - 0.036 13.6 0.0 0.18 11.4 0.0 2.2 2 0 0 2 2 2 0 EF-hand domain pair CENP-F_leu_zip PF10473.4 EIW85357.1 - 0.63 9.8 30.5 0.056 13.2 5.3 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.6 EIW85357.1 - 8.6 4.9 25.1 0.35 9.5 11.2 2.5 1 1 2 3 3 3 0 Spc7 kinetochore protein PDEase_II PF02112.10 EIW85358.1 - 6.6e-48 163.3 0.0 1.2e-47 162.4 0.0 1.4 1 1 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EIW85358.1 - 7.2e-12 45.2 0.0 1.1e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EIW85358.1 - 0.059 13.0 0.8 0.13 11.8 0.5 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily WD40 PF00400.27 EIW85359.1 - 2.4e-48 160.3 5.8 2.4e-11 43.0 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Striatin PF08232.7 EIW85359.1 - 6.5e-40 136.5 14.8 3.9e-37 127.5 0.5 4.2 4 1 0 4 4 4 2 Striatin family Nucleoporin_N PF08801.6 EIW85359.1 - 0.017 13.8 0.1 0.017 13.8 0.0 3.0 3 2 1 5 5 5 0 Nup133 N terminal like Propeptide_C1 PF08127.8 EIW85359.1 - 0.061 12.9 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 Peptidase family C1 propeptide TMA7 PF09072.5 EIW85360.1 - 6e-17 61.8 14.0 7.7e-17 61.5 9.7 1.1 1 0 0 1 1 1 1 Translation machinery associated TMA7 V-ATPase_H_N PF03224.9 EIW85361.1 - 7.1e-83 278.2 4.9 8.1e-83 278.0 2.2 1.7 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EIW85361.1 - 6.8e-43 145.3 0.6 8.4e-42 141.8 0.1 2.5 2 0 0 2 2 2 1 V-ATPase subunit H Arm_2 PF04826.8 EIW85361.1 - 2.9e-05 23.3 0.2 8.2e-05 21.8 0.0 1.8 2 0 0 2 2 2 1 Armadillo-like HEAT_2 PF13646.1 EIW85361.1 - 6.8e-05 23.0 3.0 0.0058 16.8 0.0 3.5 2 1 0 2 2 2 1 HEAT repeats Adaptin_N PF01602.15 EIW85361.1 - 0.00026 19.4 4.4 0.56 8.4 0.0 3.7 3 1 0 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.2 EIW85361.1 - 0.0087 15.9 1.3 0.3 10.9 0.5 2.8 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EIW85361.1 - 0.026 14.5 2.6 3.7 7.8 0.0 4.6 5 0 0 5 5 5 0 HEAT repeat DUF974 PF06159.8 EIW85362.1 - 1.3e-59 201.6 0.0 1.7e-59 201.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) RNA12 PF10443.4 EIW85363.1 - 9.6e-118 393.3 0.3 5.4e-117 390.9 0.2 2.0 1 1 0 1 1 1 1 RNA12 protein AAA_16 PF13191.1 EIW85363.1 - 1.7e-06 28.1 1.8 1.3e-05 25.3 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain RRM_1 PF00076.17 EIW85363.1 - 5.3e-06 25.9 0.0 1.9e-05 24.1 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_22 PF13401.1 EIW85363.1 - 0.0008 19.5 0.1 0.01 15.9 0.1 2.6 1 1 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EIW85363.1 - 0.0011 18.6 1.3 0.0096 15.6 0.0 2.8 3 0 0 3 3 3 1 Archaeal ATPase RRM_5 PF13893.1 EIW85363.1 - 0.0035 17.1 0.0 0.0086 15.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_24 PF13479.1 EIW85363.1 - 0.0036 16.9 0.0 0.0075 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EIW85363.1 - 0.0041 16.8 0.3 0.82 9.4 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain RRM_6 PF14259.1 EIW85363.1 - 0.0043 16.9 0.0 0.015 15.2 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) eRF1_3 PF03465.10 EIW85363.1 - 0.009 16.2 0.1 0.023 14.9 0.1 1.7 1 0 0 1 1 1 1 eRF1 domain 3 AAA_25 PF13481.1 EIW85363.1 - 0.033 13.5 0.4 1.2 8.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA PF00004.24 EIW85363.1 - 0.063 13.4 0.3 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 EIW85363.1 - 0.084 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EIW85363.1 - 0.095 12.6 0.0 0.39 10.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Nucleoporin_FG PF13634.1 EIW85364.1 - 0.0041 17.3 24.7 0.0041 17.3 17.1 8.8 4 3 3 7 7 7 3 Nucleoporin FG repeat region Tubulin PF00091.20 EIW85365.1 - 1.6e-73 247.1 0.0 2.7e-73 246.3 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EIW85365.1 - 1.3e-47 160.9 0.1 2.8e-47 159.8 0.0 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EIW85365.1 - 0.00035 20.6 0.0 0.0013 18.7 0.0 1.9 1 1 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EIW85365.1 - 0.00044 19.7 0.0 0.00087 18.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain LGFP PF08310.6 EIW85365.1 - 0.086 12.4 0.1 0.19 11.3 0.1 1.6 1 0 0 1 1 1 0 LGFP repeat FAD-oxidase_C PF02913.14 EIW85366.1 - 5e-57 193.0 0.0 8.8e-57 192.2 0.0 1.4 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EIW85366.1 - 5.4e-30 103.6 0.0 1e-29 102.7 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain DUF3321 PF11968.3 EIW85367.1 - 1.2e-62 211.3 0.0 1.5e-62 211.1 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EIW85367.1 - 3.5e-05 23.5 0.0 9e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW85367.1 - 0.039 14.5 0.0 0.066 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EIW85367.1 - 0.053 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Tetraspannin PF00335.15 EIW85368.1 - 0.00025 20.4 21.5 0.00039 19.7 14.9 1.4 1 1 0 1 1 1 1 Tetraspanin family TIG PF01833.19 EIW85368.1 - 0.015 15.3 0.1 0.023 14.6 0.1 1.3 1 0 0 1 1 1 0 IPT/TIG domain DUF4191 PF13829.1 EIW85368.1 - 0.46 9.5 4.1 1.7 7.7 0.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4191) DUF3169 PF11368.3 EIW85368.1 - 1.2 8.2 5.5 1.4 8.0 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3169) AMO PF02461.11 EIW85368.1 - 2.6 7.7 7.0 0.24 11.0 2.0 1.4 2 0 0 2 2 2 0 Ammonia monooxygenase NAD_binding_7 PF13241.1 EIW85369.1 - 1.1e-28 99.5 0.0 2.3e-28 98.4 0.0 1.6 2 0 0 2 2 2 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EIW85369.1 - 1e-17 63.1 0.1 1.7e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EIW85369.1 - 1e-14 53.2 0.2 1.6e-14 52.5 0.1 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central 5_nucleotid_C PF02872.13 EIW85370.1 - 8.2e-24 84.3 0.0 1.6e-23 83.3 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EIW85370.1 - 3.2e-10 39.7 0.2 6e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PGA_cap PF09587.5 EIW85370.1 - 2.2e-05 23.9 0.0 3.9e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap DUF2420 PF10336.4 EIW85371.1 - 5.7e-14 51.6 0.0 1.1e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) RNA_pol_Rpc82 PF05645.8 EIW85372.1 - 4e-20 72.4 1.9 1.2e-18 67.5 3.0 2.1 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EIW85372.1 - 5.1e-15 55.0 1.0 4.3e-13 48.9 0.0 3.7 4 0 0 4 4 4 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EIW85372.1 - 1.9e-08 33.7 1.2 1.8e-06 27.3 0.0 3.4 3 1 1 4 4 4 1 TFIIE alpha subunit Penicillinase_R PF03965.11 EIW85372.1 - 0.008 16.2 0.3 0.28 11.2 0.0 3.0 3 0 0 3 3 3 1 Penicillinase repressor Metallophos PF00149.23 EIW85373.1 - 2.6e-09 36.7 0.2 1.3e-08 34.5 0.2 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIW85373.1 - 1.7e-06 27.9 0.0 5.2e-06 26.3 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF572 PF04502.8 EIW85374.1 - 1.6e-87 293.7 6.0 2e-87 293.4 4.2 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.9 EIW85374.1 - 0.018 14.6 1.1 0.37 10.4 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF866 PF05907.8 EIW85374.1 - 0.026 13.9 0.1 0.05 13.0 0.1 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Lar_restr_allev PF14354.1 EIW85374.1 - 0.12 12.6 0.8 2.4 8.5 0.5 2.5 1 1 0 1 1 1 0 Restriction alleviation protein Lar eIF3_subunit PF08597.5 EIW85374.1 - 6.7 6.2 17.0 0.63 9.5 8.1 1.6 1 1 1 2 2 2 0 Translation initiation factor eIF3 subunit SPT16 PF08644.6 EIW85375.1 - 7.7e-57 191.4 0.6 2.2e-56 189.9 0.4 1.8 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EIW85375.1 - 1.8e-35 121.8 0.0 6.8e-35 120.0 0.0 2.1 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.7 EIW85375.1 - 5.7e-22 77.5 0.0 1.6e-21 76.0 0.0 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Peptidase_M24 PF00557.19 EIW85375.1 - 2.4e-21 76.2 0.0 3.9e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Abhydrolase_6 PF12697.2 EIW85376.1 - 3.2e-32 112.2 0.0 4e-32 111.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW85376.1 - 4.8e-19 68.8 0.0 2.3e-18 66.5 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EIW85376.1 - 1.5e-14 54.0 0.0 2.6e-14 53.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EIW85376.1 - 9.4e-05 22.2 0.0 0.00019 21.2 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein DLH PF01738.13 EIW85376.1 - 0.00025 20.4 0.0 0.42 9.8 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Esterase PF00756.15 EIW85376.1 - 0.0004 19.8 0.0 0.00071 19.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 EIW85376.1 - 0.0019 17.4 0.7 0.22 10.6 0.1 2.5 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EIW85376.1 - 0.007 15.9 0.2 0.058 12.9 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EIW85376.1 - 0.01 15.7 0.0 0.63 9.9 0.0 2.4 2 0 0 2 2 2 1 Putative lysophospholipase UPF0227 PF05728.7 EIW85376.1 - 0.01 15.5 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) BAAT_C PF08840.6 EIW85376.1 - 0.012 15.3 0.0 1.9 8.1 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S15 PF02129.13 EIW85376.1 - 0.056 12.8 0.1 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Thioesterase PF00975.15 EIW85376.1 - 0.058 13.6 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain TPP_enzyme_C PF02775.16 EIW85376.1 - 0.077 12.5 0.1 1.4 8.4 0.0 2.4 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DEAD PF00270.24 EIW85377.1 - 1.1e-20 73.8 0.0 2.1e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW85377.1 - 2.8e-12 46.3 0.0 3.5e-10 39.5 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 EIW85377.1 - 5.5e-10 39.6 0.8 1.5e-09 38.2 0.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) CDT1 PF08839.6 EIW85377.1 - 1.9e-07 31.1 0.0 8.8e-07 29.0 0.0 2.0 2 0 0 2 2 2 1 DNA replication factor CDT1 like JAB PF01398.16 EIW85377.1 - 0.16 11.7 0.1 0.38 10.5 0.1 1.6 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Pkinase PF00069.20 EIW85378.1 - 6.5e-22 77.9 0.0 9.9e-22 77.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW85378.1 - 5.4e-13 48.6 0.0 1.2e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase NAD_binding_2 PF03446.10 EIW85379.1 - 5.3e-38 130.4 0.1 9.7e-38 129.5 0.1 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EIW85379.1 - 9.5e-30 103.1 0.0 2.2e-29 101.9 0.0 1.7 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EIW85379.1 - 0.00088 19.6 0.0 0.0018 18.6 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 EIW85380.1 - 6.2e-05 22.5 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1256 PF06866.6 EIW85380.1 - 0.049 12.8 0.1 1.4 8.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1256) Pkinase PF00069.20 EIW85381.1 - 2.3e-63 213.7 0.0 2.8e-63 213.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW85381.1 - 3.4e-31 108.2 0.0 4.5e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW85381.1 - 0.00097 18.1 0.0 0.0015 17.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like MAT1 PF06391.8 EIW85382.1 - 6.9e-49 166.1 15.9 9.1e-49 165.7 11.0 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-RING_5 PF14634.1 EIW85382.1 - 8.6e-06 25.3 7.3 2.7e-05 23.7 5.2 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIW85382.1 - 1.3e-05 24.7 7.0 3.3e-05 23.4 4.9 1.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW85382.1 - 5.3e-05 22.7 5.2 0.00013 21.5 3.7 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW85382.1 - 0.0002 21.3 6.9 0.00055 19.8 5.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW85382.1 - 0.00049 19.8 7.8 0.0016 18.2 5.7 1.7 1 1 0 1 1 1 1 Ring finger domain zf-RING_4 PF14570.1 EIW85382.1 - 0.0096 15.4 4.1 0.082 12.5 0.9 2.3 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EIW85382.1 - 0.015 15.4 1.9 0.028 14.5 1.3 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger VIT1 PF01988.14 EIW85382.1 - 0.089 12.2 1.9 0.13 11.7 1.3 1.3 1 0 0 1 1 1 0 VIT family zf-RING_UBOX PF13445.1 EIW85382.1 - 0.75 9.5 4.4 4.7 7.0 3.0 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EIW85382.1 - 2.5 8.0 7.2 30 4.6 5.6 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF1682 PF07946.9 EIW85382.1 - 3.1 6.5 14.2 5.1 5.8 9.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) APG6 PF04111.7 EIW85382.1 - 5.6 5.9 12.8 9.5 5.1 8.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 Hid1 PF12722.2 EIW85382.1 - 6.6 4.2 5.7 8.6 3.8 4.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Usp PF00582.21 EIW85382.1 - 8.9 6.5 8.0 18 5.4 5.5 1.4 1 0 0 1 1 1 0 Universal stress protein family Peptidase_C78 PF07910.8 EIW85383.1 - 3.3e-41 140.8 0.0 4.6e-41 140.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 DUF1768 PF08719.6 EIW85383.1 - 0.079 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1768) Proteasome PF00227.21 EIW85384.1 - 6.3e-60 201.7 0.0 8.6e-60 201.2 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIW85384.1 - 1.3e-14 53.2 0.1 1.3e-14 53.2 0.0 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Sec7 PF01369.15 EIW85385.1 - 3.5e-62 209.4 0.8 6.3e-62 208.6 0.5 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EIW85385.1 - 8.5e-21 74.1 0.1 3.2e-09 36.4 0.0 3.2 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EIW85385.1 - 0.0035 16.8 1.2 0.99 8.9 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) Cytochrom_B561 PF03188.11 EIW85386.1 - 2.6e-13 50.0 12.4 7.2e-13 48.5 8.5 1.7 1 1 0 1 1 1 1 Eukaryotic cytochrome b561 PepSY_TM_1 PF13172.1 EIW85386.1 - 0.022 14.5 0.7 0.022 14.5 0.5 4.1 5 0 0 5 5 5 0 PepSY-associated TM helix Cyto_heme_lyase PF01265.12 EIW85387.1 - 1.1e-84 284.0 0.0 1.2e-84 283.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase NMO PF03060.10 EIW85388.1 - 2.2e-75 253.8 1.2 2.6e-75 253.6 0.8 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EIW85388.1 - 6.8e-08 31.7 1.0 1.6e-07 30.5 0.7 1.7 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EIW85388.1 - 0.031 13.1 1.5 0.053 12.3 1.0 1.3 1 0 0 1 1 1 0 FMN-dependent dehydrogenase DUF3445 PF11927.3 EIW85389.1 - 1.9e-70 237.0 0.0 2.8e-70 236.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) WD40 PF00400.27 EIW85390.1 - 3e-17 61.7 16.0 0.00013 21.7 0.0 6.6 5 3 0 5 5 5 5 WD domain, G-beta repeat LVIVD PF08309.6 EIW85390.1 - 0.0062 15.4 0.0 0.025 13.5 0.0 2.0 2 0 0 2 2 2 1 LVIVD repeat SlyX PF04102.7 EIW85391.1 - 0.0007 19.9 0.0 0.0014 18.9 0.0 1.6 1 0 0 1 1 1 1 SlyX DUF4510 PF14971.1 EIW85391.1 - 0.11 12.6 0.7 2.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4510) TPR_14 PF13428.1 EIW85392.1 - 2.1e-08 34.0 13.7 0.42 11.3 0.0 10.3 11 0 0 11 11 9 2 Tetratricopeptide repeat TPR_19 PF14559.1 EIW85392.1 - 2.1e-07 31.1 3.1 0.32 11.3 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EIW85392.1 - 1.9e-05 24.1 11.6 1.6 8.4 0.0 7.0 8 0 0 8 8 8 2 TPR repeat Suf PF05843.9 EIW85392.1 - 9.3e-05 22.2 9.8 0.011 15.4 2.3 4.8 3 1 1 4 4 4 1 Suppressor of forked protein (Suf) TPR_16 PF13432.1 EIW85392.1 - 0.00016 22.2 9.8 0.12 13.0 0.0 6.0 8 0 0 8 8 7 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EIW85392.1 - 0.00034 20.4 6.8 3.5 7.4 0.0 5.9 5 2 2 7 7 7 2 Mad3/BUB1 homology region 1 NRDE-2 PF08424.5 EIW85392.1 - 0.0024 16.8 10.1 0.041 12.7 0.0 5.2 2 2 1 4 4 4 2 NRDE-2, necessary for RNA interference TPR_2 PF07719.12 EIW85392.1 - 0.0028 17.4 19.3 0.029 14.2 0.1 7.2 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIW85392.1 - 0.068 13.1 21.5 0.12 12.2 0.2 6.4 7 2 2 9 9 8 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIW85392.1 - 0.26 11.1 8.6 32 4.6 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat DALR_1 PF05746.10 EIW85392.1 - 0.44 10.5 3.0 3.2 7.7 0.0 3.1 3 0 0 3 3 3 0 DALR anticodon binding domain HAT PF02184.11 EIW85392.1 - 1.5 8.5 12.8 3.3 7.5 0.0 5.9 8 0 0 8 8 8 0 HAT (Half-A-TPR) repeat PPTA PF01239.17 EIW85393.1 - 1.1e-43 144.8 20.2 6.7e-11 41.0 0.7 6.7 7 0 0 7 7 7 5 Protein prenyltransferase alpha subunit repeat DUF3950 PF13132.1 EIW85393.1 - 0.15 11.6 1.1 3.9 7.0 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3950) Piwi PF02171.12 EIW85395.1 - 2.6e-64 217.1 0.0 6.3e-64 215.8 0.0 1.5 1 1 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EIW85395.1 - 2.9e-10 39.3 0.0 7.1e-10 38.0 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EIW85395.1 - 4.2e-07 29.3 0.0 7.8e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 PAZ domain Lactamase_B PF00753.22 EIW85396.1 - 2.8e-25 89.1 0.1 3.9e-25 88.6 0.1 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Beta-APP PF03494.8 EIW85397.1 - 0.029 13.8 1.9 0.062 12.7 1.3 1.4 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) EphA2_TM PF14575.1 EIW85397.1 - 0.09 13.1 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Rifin_STEVOR PF02009.11 EIW85397.1 - 0.22 11.1 0.0 0.28 10.8 0.0 1.1 1 0 0 1 1 1 0 Rifin/stevor family EphA2_TM PF14575.1 EIW85398.1 - 0.11 12.8 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain SRP-alpha_N PF04086.8 EIW85399.1 - 6.2e-48 163.5 2.3 1.3e-47 162.5 1.6 1.5 1 1 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 EIW85399.1 - 4.2e-45 153.6 0.1 2.8e-44 150.9 0.1 2.3 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain CbiA PF01656.18 EIW85399.1 - 7.9e-07 28.6 0.0 2.4e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54_N PF02881.14 EIW85399.1 - 8e-07 29.0 0.0 2.5e-06 27.4 0.0 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 EIW85399.1 - 0.00017 20.4 0.1 0.00053 18.8 0.1 1.7 1 1 0 1 1 1 1 ArgK protein MobB PF03205.9 EIW85399.1 - 0.0056 16.3 0.1 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EIW85399.1 - 0.012 15.6 0.1 0.75 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.1 EIW85399.1 - 0.012 15.2 0.0 0.062 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EIW85399.1 - 0.012 15.7 0.0 0.15 12.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain Gifsy-2 PF13856.1 EIW85399.1 - 0.076 13.1 0.1 0.19 11.8 0.0 1.6 1 0 0 1 1 1 0 ATP-binding sugar transporter from pro-phage Fer4_NifH PF00142.13 EIW85399.1 - 0.086 12.0 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.10 EIW85399.1 - 0.1 11.6 0.0 2.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Anion-transporting ATPase Glyco_hydro_cc PF11790.3 EIW85400.1 - 6.1e-37 127.3 0.0 7.2e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Glyco_hydro_cc PF11790.3 EIW85402.1 - 4.5e-36 124.4 0.0 5.2e-36 124.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core SOR_SNZ PF01680.12 EIW85405.1 - 2e-112 373.8 5.5 2.8e-112 373.3 3.8 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EIW85405.1 - 2.2e-09 36.7 7.0 3e-07 29.7 0.2 2.7 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 EIW85405.1 - 4.4e-05 22.4 0.1 0.094 11.5 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.9 EIW85405.1 - 0.0029 16.6 0.4 0.12 11.3 0.0 2.5 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 EIW85405.1 - 0.0038 16.5 0.4 0.21 10.8 0.0 2.9 2 1 0 3 3 3 1 Histidine biosynthesis protein IGPS PF00218.16 EIW85405.1 - 0.0048 15.9 0.1 0.022 13.8 0.0 2.0 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase FMN_dh PF01070.13 EIW85405.1 - 0.0052 15.6 0.1 0.012 14.4 0.0 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.10 EIW85405.1 - 0.016 14.3 0.3 0.016 14.3 0.2 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase OMPdecase PF00215.19 EIW85405.1 - 0.063 12.6 0.1 1.1 8.6 0.0 2.1 1 1 1 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Img2 PF05046.9 EIW85406.1 - 5e-19 68.3 0.0 6.2e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) Ras PF00071.17 EIW85408.1 - 2.5e-65 218.8 1.1 2.9e-65 218.5 0.8 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW85408.1 - 1.8e-21 76.7 0.0 2.7e-21 76.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW85408.1 - 1.8e-17 63.1 0.2 2.2e-17 62.8 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW85408.1 - 6.8e-07 28.6 0.1 8e-07 28.4 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIW85408.1 - 1.1e-06 28.2 0.2 2.4e-06 27.1 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EIW85408.1 - 2.4e-05 23.6 0.1 2.9e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EIW85408.1 - 2.7e-05 24.0 0.1 4.5e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EIW85408.1 - 0.00098 19.2 0.0 0.0021 18.1 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EIW85408.1 - 0.0034 17.5 0.0 0.33 11.1 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.13 EIW85408.1 - 0.0073 15.5 0.1 0.04 13.1 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EIW85408.1 - 0.011 14.9 0.2 0.044 12.9 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EIW85408.1 - 0.016 15.2 0.1 0.066 13.1 0.0 2.0 1 1 1 2 2 2 0 AAA ATPase domain AAA_5 PF07728.9 EIW85408.1 - 0.026 14.2 0.0 0.044 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EIW85408.1 - 0.027 14.0 0.0 0.083 12.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EIW85408.1 - 0.034 14.0 0.2 0.18 11.7 0.1 2.0 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 EIW85408.1 - 0.071 12.1 0.0 0.18 10.8 0.0 1.6 2 0 0 2 2 2 0 Septin ABC_tran PF00005.22 EIW85408.1 - 0.074 13.3 0.0 0.11 12.7 0.0 1.5 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EIW85408.1 - 0.075 12.5 0.1 1.1 8.7 0.0 2.3 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.15 EIW85408.1 - 1.5 7.4 4.2 16 4.0 0.1 2.7 1 1 1 2 2 2 0 G-protein alpha subunit Asp PF00026.18 EIW85409.1 - 1.3e-45 156.0 0.0 1.7e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW85409.1 - 4.4e-08 33.2 0.2 7.8e-08 32.4 0.2 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIW85409.1 - 0.087 13.3 1.8 0.73 10.3 0.3 3.0 2 1 0 2 2 2 0 Aspartyl protease Zn_Tnp_IS1595 PF12760.2 EIW85410.1 - 0.0012 18.6 2.9 0.0063 16.3 2.0 1.9 1 1 0 1 1 1 1 Transposase zinc-ribbon domain Rubredoxin PF00301.15 EIW85410.1 - 0.061 13.2 3.8 0.18 11.7 0.1 2.8 3 0 0 3 3 3 0 Rubredoxin FYVE_2 PF02318.11 EIW85410.1 - 0.18 11.7 2.1 6.8 6.6 0.1 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger zf-Sec23_Sec24 PF04810.10 EIW85410.1 - 0.19 11.3 2.1 0.5 9.9 0.1 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger EF-hand_1 PF00036.27 EIW85411.1 - 4.9e-22 75.4 0.7 2.3e-05 23.3 0.0 4.9 4 1 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EIW85411.1 - 5.5e-19 66.2 1.0 4.7e-05 22.9 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 EIW85411.1 - 1.8e-16 60.0 0.7 2.5e-07 30.7 0.0 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EIW85411.1 - 3e-13 48.4 0.3 0.0017 17.5 0.0 4.1 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EIW85411.1 - 3.6e-12 45.6 2.0 4.8e-05 22.8 0.0 4.2 3 1 1 4 4 4 4 EF-hand domain pair Zn_clus PF00172.13 EIW85412.1 - 4.4e-06 26.4 5.7 4.4e-06 26.4 3.9 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Nop16 PF09420.5 EIW85413.1 - 1.6e-37 129.1 0.6 2.2e-37 128.6 0.4 1.2 1 0 0 1 1 1 1 Ribosome biogenesis protein Nop16 HAD_2 PF13419.1 EIW85414.1 - 6.9e-19 68.7 0.0 1.1e-13 51.8 0.0 2.3 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIW85414.1 - 6.2e-05 22.6 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.2 EIW85414.1 - 0.011 15.3 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 Acid Phosphatase QCR10 PF09796.4 EIW85415.1 - 5.7e-15 54.7 0.1 6.6e-15 54.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Glyco_hydro_18 PF00704.23 EIW85416.1 - 4.3e-58 197.4 5.7 5.1e-58 197.1 3.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF187 PF02638.10 EIW85416.1 - 0.024 13.4 0.1 0.072 11.9 0.0 1.7 1 1 1 2 2 2 0 Glycosyl hydrolase like GH101 2OG-FeII_Oxy_2 PF13532.1 EIW85417.1 - 7.1e-24 84.7 0.0 1.1e-23 84.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_M24 PF00557.19 EIW85418.1 - 4.3e-43 147.3 0.3 6.3e-43 146.7 0.2 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EIW85418.1 - 2.1e-07 31.4 0.0 4.2e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain TNV_CP PF03898.8 EIW85418.1 - 0.18 10.8 0.0 0.29 10.1 0.0 1.2 1 0 0 1 1 1 0 Satellite tobacco necrosis virus coat protein MFS_1 PF07690.11 EIW85420.1 - 1.3e-25 89.8 25.7 2.2e-25 89.1 17.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily ATG22 PF11700.3 EIW85420.1 - 0.0009 17.8 2.7 0.0009 17.8 1.8 3.4 2 1 0 2 2 2 1 Vacuole effluxer Atg22 like AMP-binding PF00501.23 EIW85421.1 - 4.1e-85 285.6 0.0 5.7e-85 285.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIW85421.1 - 0.025 15.5 0.0 0.055 14.4 0.0 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Glyco_hydro_cc PF11790.3 EIW85422.1 - 3.6e-63 213.1 3.3 4.3e-63 212.9 2.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core zf-Mss51 PF13824.1 EIW85423.1 - 7.1e-23 80.2 10.5 1.3e-22 79.3 7.3 1.5 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 Lar_restr_allev PF14354.1 EIW85423.1 - 2.6 8.4 6.7 7.2 6.9 4.7 1.7 1 0 0 1 1 1 0 Restriction alleviation protein Lar Peptidase_M13_N PF05649.8 EIW85424.1 - 3.6e-90 302.8 0.0 4.7e-90 302.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EIW85424.1 - 1.5e-56 190.8 0.1 3.2e-56 189.7 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M13 Mucin PF01456.12 EIW85424.1 - 0.0025 17.6 15.6 0.0044 16.7 10.8 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein CDC45 PF02724.9 EIW85425.1 - 3e-182 606.9 0.0 3.6e-182 606.6 0.0 1.0 1 0 0 1 1 1 1 CDC45-like protein DHH PF01368.15 EIW85425.1 - 0.0079 15.8 0.0 0.1 12.2 0.0 2.1 2 0 0 2 2 2 1 DHH family Prothymosin PF03247.9 EIW85425.1 - 0.017 15.2 18.8 0.017 15.2 13.1 2.0 2 0 0 2 2 2 0 Prothymosin/parathymosin family Spt5_N PF11942.3 EIW85425.1 - 0.04 14.5 17.4 0.13 12.8 12.1 1.9 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Nop14 PF04147.7 EIW85425.1 - 0.21 9.4 11.3 0.3 8.9 7.8 1.1 1 0 0 1 1 1 0 Nop14-like family Scramblase PF03803.10 EIW85426.1 - 5.9e-58 195.5 0.0 7.2e-58 195.2 0.0 1.1 1 0 0 1 1 1 1 Scramblase GTP_EFTU PF00009.22 EIW85427.1 - 1.1e-39 135.8 2.3 6.4e-39 133.3 1.6 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EIW85427.1 - 2.5e-28 98.1 2.4 6.6e-28 96.7 1.1 2.1 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EIW85427.1 - 9.3e-08 32.0 7.6 0.00052 20.0 0.0 3.8 4 1 0 4 4 4 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIW85427.1 - 1.6e-07 31.2 1.5 3.2e-07 30.3 0.1 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.16 EIW85427.1 - 1.4e-06 27.6 0.0 1e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 EIW85427.1 - 0.00011 22.7 0.1 0.00031 21.2 0.1 1.8 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 EIW85427.1 - 0.00057 19.1 0.1 0.002 17.4 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 EIW85427.1 - 0.00094 18.4 0.0 0.0018 17.4 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EIW85427.1 - 0.0014 18.1 0.6 0.017 14.6 0.4 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EIW85427.1 - 0.026 14.2 0.7 0.078 12.6 0.3 1.9 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU_D4 PF14578.1 EIW85427.1 - 0.39 10.4 9.5 0.29 10.7 0.2 4.3 4 1 0 5 5 5 0 Elongation factor Tu domain 4 Dynamin_N PF00350.18 EIW85427.1 - 0.77 9.5 4.7 12 5.6 0.1 2.8 3 0 0 3 3 3 0 Dynamin family CHORD PF04968.7 EIW85428.1 - 5.5e-52 173.8 10.4 1.9e-26 92.0 2.0 2.3 2 0 0 2 2 2 2 CHORD CS PF04969.11 EIW85428.1 - 4e-15 56.1 1.1 6.4e-15 55.4 0.7 1.3 1 0 0 1 1 1 1 CS domain Mito_carr PF00153.22 EIW85429.1 - 5.1e-12 45.3 0.0 0.00012 21.7 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein 2OG-FeII_Oxy_2 PF13532.1 EIW85430.1 - 1.5e-10 41.2 0.0 2.1e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Asp_Arg_Hydrox PF05118.10 EIW85430.1 - 0.014 15.2 0.0 0.019 14.8 0.0 1.1 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase WD40 PF00400.27 EIW85431.1 - 1e-48 161.5 14.6 1.2e-12 47.1 0.2 7.8 8 0 0 8 8 8 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EIW85431.1 - 3e-06 26.2 3.0 0.0023 16.7 0.1 3.7 1 1 2 3 3 3 2 Nup133 N terminal like Nup160 PF11715.3 EIW85431.1 - 1.6e-05 23.2 3.4 0.22 9.6 0.0 3.7 1 1 1 4 4 4 3 Nucleoporin Nup120/160 Hira PF07569.6 EIW85431.1 - 8.5e-05 21.8 0.3 0.63 9.2 0.0 3.2 3 1 1 4 4 4 2 TUP1-like enhancer of split Nbas_N PF15492.1 EIW85431.1 - 0.0054 15.8 0.5 4.3 6.3 0.0 4.0 2 2 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal DUF3312 PF11768.3 EIW85431.1 - 0.057 11.6 0.0 0.087 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) Glu_synthase PF01645.12 EIW85432.1 - 5.7e-158 525.6 0.0 1.1e-157 524.7 0.0 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EIW85432.1 - 3.5e-136 453.6 0.0 4.7e-136 453.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EIW85432.1 - 6e-118 393.2 0.0 8.9e-118 392.7 0.0 1.2 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EIW85432.1 - 8.6e-68 227.3 3.6 1.7e-67 226.3 2.5 1.5 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EIW85432.1 - 5.8e-23 80.6 0.1 1.3e-22 79.4 0.0 1.6 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EIW85432.1 - 8.7e-17 61.6 0.0 2.1e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW85432.1 - 2.1e-10 41.0 0.1 0.00019 21.5 0.1 2.8 2 1 1 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW85432.1 - 6.4e-08 32.5 0.0 2.7e-07 30.5 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EIW85432.1 - 8.9e-07 29.2 0.4 0.00065 20.0 0.1 3.5 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW85432.1 - 9.1e-07 28.0 0.2 0.00022 20.2 0.0 2.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EIW85432.1 - 7.3e-05 21.4 0.8 0.00016 20.3 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EIW85432.1 - 0.00042 19.2 0.2 0.0065 15.3 0.0 2.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_7 PF13241.1 EIW85432.1 - 0.00079 19.6 0.7 0.091 13.0 0.0 2.7 2 0 0 2 2 2 1 Putative NAD(P)-binding FMN_dh PF01070.13 EIW85432.1 - 0.00084 18.2 0.9 0.014 14.2 0.5 2.4 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Amino_oxidase PF01593.19 EIW85432.1 - 0.0014 17.8 0.0 0.0039 16.3 0.0 1.7 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 EIW85432.1 - 0.0029 16.7 0.0 0.0064 15.5 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EIW85432.1 - 0.019 14.0 1.7 0.019 14.0 0.1 1.8 2 0 0 2 2 2 0 Thi4 family AlaDh_PNT_C PF01262.16 EIW85432.1 - 0.021 14.3 0.1 0.14 11.7 0.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GATase_6 PF13522.1 EIW85432.1 - 0.056 13.4 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 Glutamine amidotransferase domain FMO-like PF00743.14 EIW85432.1 - 0.061 11.5 0.0 7.1 4.6 0.0 2.8 3 0 0 3 3 3 0 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 EIW85432.1 - 0.076 12.7 0.0 0.28 10.9 0.0 2.0 1 0 0 1 1 1 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 EIW85432.1 - 0.082 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EIW85432.1 - 0.1 12.2 0.1 0.31 10.6 0.1 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EIW85432.1 - 0.12 11.4 0.0 0.49 9.5 0.0 2.0 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EIW85432.1 - 0.21 10.9 0.1 0.5 9.7 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Shikimate_DH PF01488.15 EIW85432.1 - 0.21 11.6 0.4 58 3.7 0.0 3.4 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF1449 PF07290.6 EIW85433.1 - 0.046 13.0 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) Acetyltransf_13 PF13880.1 EIW85434.1 - 9.7e-12 44.4 0.0 1.7e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EIW85434.1 - 5.3e-09 35.5 0.1 8.4e-09 34.8 0.1 1.3 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.19 EIW85434.1 - 0.09 12.8 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Nudix_N_2 PF14803.1 EIW85434.1 - 0.11 12.2 0.8 0.25 11.0 0.5 1.6 1 0 0 1 1 1 0 Nudix N-terminal Pectate_lyase_3 PF12708.2 EIW85435.1 - 5.2e-77 258.9 21.4 1.7e-62 211.4 7.0 2.8 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EIW85435.1 - 1.5e-07 30.7 2.3 0.0038 16.6 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Cellulase PF00150.13 EIW85436.1 - 8.5e-10 38.2 0.0 1.5e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Protocadherin PF08374.6 EIW85436.1 - 0.06 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Protocadherin DUF1180 PF06679.7 EIW85436.1 - 0.2 11.5 0.0 0.2 11.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) DUF515 PF04415.7 EIW85436.1 - 0.32 9.1 0.0 0.48 8.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) IATP PF04568.7 EIW85437.1 - 7.7e-09 35.4 2.3 7.7e-09 35.4 1.6 1.7 1 1 1 2 2 2 1 Mitochondrial ATPase inhibitor, IATP Herpes_PAP PF03325.8 EIW85437.1 - 0.23 10.9 1.5 0.26 10.7 1.1 1.0 1 0 0 1 1 1 0 Herpesvirus polymerase accessory protein FAD_binding_3 PF01494.14 EIW85438.1 - 5.9e-26 91.3 0.0 1.5e-25 89.9 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIW85438.1 - 2.7e-09 36.4 0.1 6.5e-05 22.0 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW85438.1 - 4.9e-06 26.8 0.2 0.0083 16.5 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EIW85438.1 - 0.00053 19.9 0.0 0.0019 18.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EIW85438.1 - 0.00072 18.5 0.5 0.29 10.0 0.0 3.0 3 0 0 3 3 3 1 Lycopene cyclase protein SE PF08491.5 EIW85438.1 - 0.0022 16.8 0.0 0.3 9.8 0.0 2.1 2 0 0 2 2 2 2 Squalene epoxidase Pyr_redox_2 PF07992.9 EIW85438.1 - 0.0054 16.6 0.0 0.016 15.0 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW85438.1 - 0.036 12.8 0.1 0.082 11.7 0.1 1.6 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EIW85438.1 - 0.064 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 EIW85438.1 - 0.1 11.4 0.1 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A UCH_1 PF13423.1 EIW85439.1 - 1.3e-43 149.5 0.0 4.3e-43 147.8 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EIW85439.1 - 8.6e-25 87.9 0.0 1.8e-24 86.9 0.0 1.6 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 EIW85439.1 - 3e-07 29.8 0.0 4.9e-06 25.8 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 EIW85439.1 - 0.52 10.2 3.8 1.3 9.0 0.1 3.2 4 0 0 4 4 4 0 WD domain, G-beta repeat FYVE PF01363.16 EIW85440.1 - 4e-16 58.6 1.6 6.4e-16 58.0 1.1 1.3 1 0 0 1 1 1 1 FYVE zinc finger Rbsn PF11464.3 EIW85440.1 - 0.021 14.3 0.2 0.045 13.3 0.1 1.6 1 0 0 1 1 1 0 Rabenosyn Rab binding domain FYVE_2 PF02318.11 EIW85440.1 - 0.028 14.3 0.4 0.059 13.2 0.3 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger zf-C2HC5 PF06221.8 EIW85440.1 - 0.15 11.8 5.0 0.3 10.8 3.4 1.4 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type SOG2 PF10428.4 EIW85443.1 - 1.3e-44 152.6 0.5 1.3e-44 152.6 0.3 3.2 2 1 0 2 2 2 1 RAM signalling pathway protein LRR_8 PF13855.1 EIW85443.1 - 4.4e-13 48.7 6.6 1e-07 31.5 1.4 3.6 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 EIW85443.1 - 3.6e-11 42.3 8.5 0.005 16.4 0.1 4.3 2 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EIW85443.1 - 9.5e-07 28.0 6.3 0.95 9.7 0.1 6.0 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.1 EIW85443.1 - 0.0092 15.9 6.4 6.5 7.1 0.0 4.9 5 0 0 5 5 5 1 Leucine Rich repeat LRR_7 PF13504.1 EIW85443.1 - 0.027 14.6 7.0 7.3 7.2 0.0 5.5 6 0 0 6 6 6 0 Leucine rich repeat Cupin_8 PF13621.1 EIW85444.1 - 2.5e-32 112.3 0.3 3.8e-32 111.7 0.2 1.2 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EIW85444.1 - 1.9e-07 30.6 0.0 7.9e-07 28.6 0.0 2.0 2 0 0 2 2 2 1 Cupin superfamily protein JmjC PF02373.17 EIW85444.1 - 0.00038 20.6 0.0 0.0058 16.8 0.0 2.3 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EIW85444.1 - 0.0018 17.7 0.0 0.005 16.3 0.0 1.7 1 0 0 1 1 1 1 Cupin domain Peptidase_M15 PF01427.12 EIW85444.1 - 0.029 13.9 0.9 0.21 11.1 0.6 2.1 1 1 0 1 1 1 0 D-ala-D-ala dipeptidase AraC_binding PF02311.14 EIW85444.1 - 0.11 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 AraC-like ligand binding domain DUF3535 PF12054.3 EIW85445.1 - 1.1e-94 317.5 0.7 9.4e-94 314.5 0.1 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EIW85445.1 - 2.9e-73 246.2 0.0 5.8e-73 245.2 0.0 1.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW85445.1 - 2.5e-12 46.4 0.0 5.9e-12 45.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.17 EIW85445.1 - 3.9e-12 45.1 23.5 0.31 11.2 0.0 10.1 10 0 0 10 10 10 6 HEAT repeat HEAT_EZ PF13513.1 EIW85445.1 - 3e-06 27.5 21.3 3.3 8.3 0.0 10.2 8 2 2 10 10 10 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EIW85445.1 - 0.00023 21.4 0.0 0.78 10.1 0.0 3.3 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 EIW85445.1 - 0.00078 19.6 16.1 0.11 12.8 0.1 8.3 9 2 0 9 9 9 1 HEAT repeats DUF1546 PF07571.8 EIW85445.1 - 0.14 12.2 0.7 14 5.9 0.0 4.3 4 1 1 5 5 5 0 Protein of unknown function (DUF1546) Ipi1_N PF12333.3 EIW85445.1 - 0.18 11.8 4.3 25 4.8 0.0 4.7 5 0 0 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation Cofilin_ADF PF00241.15 EIW85446.1 - 7.1e-20 71.1 0.1 9.6e-11 41.6 0.0 2.3 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein CoA_trans PF01144.18 EIW85447.1 - 1.5e-102 341.4 1.6 2.8e-61 206.4 0.2 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 EIW85447.1 - 0.0021 17.7 0.0 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain DeoRC PF00455.17 EIW85447.1 - 0.1 12.2 0.6 2.7 7.5 0.0 2.8 3 0 0 3 3 3 0 DeoR C terminal sensor domain CoA_trans PF01144.18 EIW85448.1 - 2.4e-102 340.7 3.6 7.4e-59 198.5 0.1 2.1 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 EIW85448.1 - 1.3e-05 24.8 0.1 2.2e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain SMI1_KNR4 PF09346.5 EIW85449.1 - 1.2e-25 90.0 0.0 3.2e-25 88.6 0.0 1.8 2 0 0 2 2 2 1 SMI1 / KNR4 family (SUKH-1) Roughex PF06020.6 EIW85449.1 - 1.2 7.7 5.3 1.9 7.0 3.7 1.2 1 0 0 1 1 1 0 Drosophila roughex protein UDG PF03167.14 EIW85450.1 - 2.8e-17 62.5 0.0 6.7e-09 35.3 0.0 2.1 2 0 0 2 2 2 2 Uracil DNA glycosylase superfamily Aldedh PF00171.17 EIW85451.1 - 1.4e-127 425.8 0.0 1.7e-127 425.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family T_cell_tran_alt PF15128.1 EIW85451.1 - 0.09 12.2 0.0 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 T-cell leukemia translocation-altered HSA PF07529.8 EIW85452.1 - 8.2e-16 57.5 1.3 8.2e-16 57.5 0.9 4.2 5 0 0 5 5 5 1 HSA Myb_DNA-bind_6 PF13921.1 EIW85452.1 - 5.9e-09 35.9 0.0 1.6e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EIW85452.1 - 0.00016 21.6 0.5 0.00071 19.5 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain MUG113 PF13455.1 EIW85453.1 - 1.7e-15 57.2 0.0 1.4e-13 51.0 0.0 2.4 1 1 1 2 2 2 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EIW85453.1 - 2e-10 40.9 0.2 1e-08 35.4 0.0 2.7 1 1 1 2 2 2 1 T5orf172 domain AAA_32 PF13654.1 EIW85453.1 - 0.026 13.1 0.0 0.037 12.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain Sas10_Utp3 PF04000.10 EIW85454.1 - 3.5e-10 39.9 0.1 8.5e-10 38.7 0.1 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Copper-bind PF00127.15 EIW85455.1 - 1.2e-06 28.7 4.1 0.011 16.0 0.4 3.0 2 2 0 2 2 2 2 Copper binding proteins, plastocyanin/azurin family Cu_bind_like PF02298.12 EIW85455.1 - 1e-05 25.2 1.0 0.012 15.3 0.0 2.8 2 1 0 2 2 2 2 Plastocyanin-like domain Cupredoxin_1 PF13473.1 EIW85455.1 - 3.8e-05 23.5 0.0 0.038 13.8 0.0 2.5 2 0 0 2 2 2 2 Cupredoxin-like domain DUF11 PF01345.13 EIW85455.1 - 6.1 6.9 12.5 0.82 9.7 0.1 4.0 5 0 0 5 5 5 0 Domain of unknown function DUF11 Herpes_capsid PF06112.6 EIW85455.1 - 7.4 6.6 25.2 7.6 6.5 3.9 2.3 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein dsDNA_bind PF01984.15 EIW85456.1 - 4.2e-25 87.7 9.1 5.1e-25 87.5 6.3 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain PCI PF01399.22 EIW85456.1 - 0.023 15.0 0.0 0.033 14.5 0.0 1.3 1 1 0 1 1 1 0 PCI domain PB1-F2 PF11986.3 EIW85456.1 - 0.073 13.1 0.3 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 Influenza A Proapoptotic protein Glyco_hydro_cc PF11790.3 EIW85457.1 - 1.4e-69 234.1 2.3 1.6e-69 233.9 1.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Cellulase PF00150.13 EIW85457.1 - 0.019 14.1 0.3 0.11 11.6 0.1 2.0 2 0 0 2 2 2 0 Cellulase (glycosyl hydrolase family 5) zf-RING_4 PF14570.1 EIW85458.1 - 2.8e-21 74.8 12.1 4.7e-21 74.0 8.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.1 EIW85458.1 - 1.8e-05 24.3 8.1 3.2e-05 23.5 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ubiquitin_2 PF14560.1 EIW85458.1 - 0.00019 21.6 0.1 0.00048 20.3 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EIW85458.1 - 0.00028 20.2 0.1 0.00075 18.8 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family CAF-1_p150 PF11600.3 EIW85458.1 - 0.00036 19.9 28.0 0.00036 19.9 19.4 3.3 3 1 0 3 3 3 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal zf-C3HC4_2 PF13923.1 EIW85458.1 - 0.0066 16.4 12.9 0.012 15.6 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.17 EIW85458.1 - 0.012 15.2 0.0 0.029 13.9 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-UDP PF14569.1 EIW85458.1 - 0.036 13.8 3.0 0.083 12.6 2.1 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger Baculo_IE-1 PF05290.6 EIW85458.1 - 0.048 13.3 3.1 0.089 12.5 2.2 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) RRM_5 PF13893.1 EIW85458.1 - 0.2 11.4 0.0 0.57 10.0 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cullin_binding PF03556.10 EIW85460.1 - 3.6e-28 98.0 0.6 5.1e-28 97.5 0.4 1.2 1 0 0 1 1 1 1 Cullin binding DUF59 PF01883.14 EIW85461.1 - 2.3e-09 37.1 0.1 4.3e-09 36.2 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF59 PI-PLC-X PF00388.14 EIW85462.1 - 1.7e-05 24.2 0.0 3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Lysine_decarbox PF03641.9 EIW85463.1 - 1.4e-33 115.5 0.0 2.1e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase tRNA-synt_1b PF00579.20 EIW85464.1 - 3.5e-19 69.0 0.0 1e-18 67.5 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) TBP PF00352.16 EIW85465.1 - 1.5e-68 226.1 0.1 3.6e-34 115.9 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EIW85465.1 - 0.00041 20.3 0.0 0.86 9.7 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Glyco_hydro_88 PF07470.8 EIW85467.1 - 4.9e-16 58.6 0.1 6.7e-16 58.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.8 EIW85467.1 - 0.051 12.8 0.4 0.41 9.8 0.0 2.1 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus HXXEE PF13787.1 EIW85468.1 - 0.011 16.0 2.3 0.011 16.0 1.6 3.4 3 1 1 4 4 4 0 Protein of unknown function with HXXEE motif DUF3483 PF11982.3 EIW85468.1 - 0.019 14.2 1.1 0.031 13.5 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) DUF3899 PF13038.1 EIW85468.1 - 1.3 9.2 0.1 1.3 9.2 0.0 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF3899) Dynamin_M PF01031.15 EIW85471.1 - 2.1e-104 348.4 0.0 3.2e-104 347.8 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.18 EIW85471.1 - 1.2e-53 181.3 0.0 3e-53 180.1 0.0 1.7 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EIW85471.1 - 4.7e-29 100.1 3.6 1.4e-28 98.6 2.5 1.9 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EIW85471.1 - 0.002 18.0 0.9 0.019 14.9 0.1 2.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EIW85471.1 - 0.11 12.9 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein NTF2 PF02136.15 EIW85474.1 - 6.2e-34 116.8 0.1 6.9e-34 116.7 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.1 EIW85474.1 - 0.14 11.1 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Baculo_PEP_C PF04513.7 EIW85475.1 - 0.015 15.0 0.2 3.8 7.3 0.0 2.2 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ytp1 PF10355.4 EIW85476.1 - 2.5e-63 213.8 8.6 3.2e-63 213.4 5.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) EphA2_TM PF14575.1 EIW85477.1 - 0.098 13.0 0.1 4 7.9 0.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 EIW85477.1 - 0.11 10.6 0.9 0.61 8.2 0.0 2.1 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Mis12 PF05859.7 EIW85478.1 - 6.1e-23 81.2 0.0 9.1e-23 80.6 0.0 1.3 1 0 0 1 1 1 1 Mis12 protein Lzipper-MIP1 PF14389.1 EIW85478.1 - 0.02 14.9 2.2 0.053 13.6 1.5 1.7 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 OrfB_IS605 PF01385.14 EIW85478.1 - 2.4 7.5 6.0 11 5.3 2.8 2.1 2 0 0 2 2 2 0 Probable transposase Pyr_redox_2 PF07992.9 EIW85480.1 - 7.2e-38 130.4 0.0 2.3e-37 128.8 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EIW85480.1 - 2.9e-34 117.4 0.0 5.2e-34 116.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EIW85480.1 - 2e-21 76.1 1.8 8.6e-19 67.7 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW85480.1 - 6.3e-14 52.5 0.0 1e-08 35.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EIW85480.1 - 3.4e-07 29.7 0.0 4.4e-06 26.0 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EIW85480.1 - 3.1e-06 25.9 1.1 0.016 13.7 0.0 2.9 3 0 0 3 3 3 2 HI0933-like protein FAD_binding_2 PF00890.19 EIW85480.1 - 3e-05 23.0 0.9 0.027 13.3 0.7 2.7 3 0 0 3 3 3 2 FAD binding domain K_oxygenase PF13434.1 EIW85480.1 - 5.7e-05 22.1 0.0 0.00018 20.5 0.0 1.7 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 EIW85480.1 - 0.0031 16.4 0.3 0.013 14.4 0.0 2.2 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EIW85480.1 - 0.0099 15.8 0.4 0.0099 15.8 0.3 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EIW85480.1 - 0.077 12.0 0.1 0.19 10.7 0.1 1.6 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EIW85480.1 - 0.078 12.7 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EIW85480.1 - 0.14 11.7 1.2 0.98 9.0 0.1 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.19 EIW85480.1 - 0.16 10.8 4.1 0.52 9.1 0.0 2.8 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EIW85480.1 - 0.27 10.2 3.6 2.5 7.0 0.5 2.8 2 1 1 3 3 3 0 FAD binding domain PPP1R35_C PF15503.1 EIW85481.1 - 0.033 13.7 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus DUF2514 PF10721.4 EIW85483.1 - 1 9.0 19.0 0.16 11.6 6.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2514) V_ATPase_I PF01496.14 EIW85484.1 - 0.13 10.1 0.0 0.16 9.7 0.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMEM154 PF15102.1 EIW85484.1 - 2.1 8.0 13.3 0.041 13.5 3.8 2.0 2 1 0 2 2 2 0 TMEM154 protein family TMEM51 PF15345.1 EIW85485.1 - 0.0026 17.4 0.1 0.0044 16.7 0.1 1.5 1 0 0 1 1 1 1 Transmembrane protein 51 MLANA PF14991.1 EIW85485.1 - 0.017 15.1 0.2 5.9 6.9 0.0 2.2 2 0 0 2 2 2 0 Protein melan-A TMEM154 PF15102.1 EIW85485.1 - 0.024 14.3 0.7 0.04 13.6 0.3 1.5 1 1 0 1 1 1 0 TMEM154 protein family RCR PF12273.3 EIW85485.1 - 0.038 14.5 0.3 0.28 11.7 0.0 2.2 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red DUF3481 PF11980.3 EIW85485.1 - 0.049 13.4 0.1 0.086 12.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3481) Herpes_gE PF02480.11 EIW85485.1 - 0.06 11.5 0.1 0.078 11.2 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4446 PF14584.1 EIW85485.1 - 0.085 12.6 0.1 0.23 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) EphA2_TM PF14575.1 EIW85485.1 - 0.094 13.1 0.3 0.17 12.3 0.2 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain PspB PF06667.7 EIW85485.1 - 0.099 12.5 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 Phage shock protein B Vpu PF00558.14 EIW85485.1 - 0.1 12.1 0.1 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Vpu protein Rifin_STEVOR PF02009.11 EIW85485.1 - 0.25 10.9 2.3 0.38 10.3 1.6 1.3 1 0 0 1 1 1 0 Rifin/stevor family P12 PF12669.2 EIW85485.1 - 0.32 11.2 2.1 0.57 10.4 1.4 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family p450 PF00067.17 EIW85486.1 - 5.8e-59 199.8 0.0 7.1e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 SKG6 PF08693.5 EIW85487.1 - 0.019 14.2 0.7 0.044 13.1 0.5 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PDGLE PF13190.1 EIW85487.1 - 0.033 13.8 0.7 0.09 12.4 0.5 1.7 1 0 0 1 1 1 0 PDGLE domain Hat1_N PF10394.4 EIW85488.1 - 3.8e-36 124.5 0.3 6.5e-36 123.8 0.2 1.4 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.1 EIW85488.1 - 0.0016 18.5 0.0 0.0033 17.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 EIW85488.1 - 0.0029 16.8 0.2 0.0046 16.2 0.1 1.3 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_7 PF13508.1 EIW85488.1 - 0.032 14.3 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EIW85488.1 - 0.034 14.3 0.1 0.91 9.6 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain CUE PF02845.11 EIW85489.1 - 3.3e-09 36.0 0.1 5.8e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 CUE domain PAT1 PF09770.4 EIW85490.1 - 5.9 5.0 22.3 7.5 4.6 15.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 O-FucT PF10250.4 EIW85491.1 - 1.8e-08 33.9 0.0 0.0069 15.5 0.0 2.8 3 0 0 3 3 3 2 GDP-fucose protein O-fucosyltransferase Herpes_gE PF02480.11 EIW85492.1 - 0.025 12.8 0.0 0.045 12.0 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E F-box-like PF12937.2 EIW85493.1 - 0.0014 18.3 0.7 0.004 16.8 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 EIW85495.1 - 0.0042 16.7 0.1 0.011 15.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIW85496.1 - 0.018 14.7 0.8 0.16 11.7 0.1 2.4 2 0 0 2 2 2 0 F-box-like LRR_4 PF12799.2 EIW85496.1 - 0.16 11.6 1.0 9 6.0 0.1 3.6 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) zf-RING_2 PF13639.1 EIW85498.1 - 5.4e-08 32.5 12.0 5.4e-08 32.5 8.4 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIW85498.1 - 5.9e-08 32.6 12.0 5.9e-08 32.6 8.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EIW85498.1 - 7e-08 32.1 6.1 1.7e-07 30.9 4.2 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4 PF00097.20 EIW85498.1 - 8.3e-08 31.7 10.1 8.3e-08 31.7 7.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW85498.1 - 4e-07 29.6 14.5 6.4e-07 28.9 7.6 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EIW85498.1 - 1.1e-06 28.1 10.2 1.1e-06 28.1 7.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EIW85498.1 - 3.9e-05 23.2 6.0 0.00011 21.7 4.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger SAP PF02037.22 EIW85498.1 - 0.00016 21.0 0.8 0.0012 18.2 0.0 2.3 2 0 0 2 2 2 1 SAP domain zf-rbx1 PF12678.2 EIW85498.1 - 0.0052 16.8 4.8 0.0052 16.8 3.3 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger U-box PF04564.10 EIW85498.1 - 0.012 15.5 0.1 0.069 13.1 0.0 2.3 3 0 0 3 3 3 0 U-box domain PRP21_like_P PF12230.3 EIW85498.1 - 0.019 14.4 0.1 0.019 14.4 0.1 2.0 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Herpes_U30 PF04523.8 EIW85498.1 - 0.034 11.6 0.0 0.049 11.0 0.0 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 zf-Nse PF11789.3 EIW85498.1 - 0.49 9.9 8.2 0.046 13.2 2.0 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EIW85498.1 - 0.53 10.2 16.6 0.072 12.9 8.3 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EIW85498.1 - 1 9.2 7.2 0.3 10.9 2.7 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 EIW85498.1 - 4.7 7.0 12.7 18 5.2 0.0 2.8 2 1 1 3 3 3 0 Double zinc ribbon Rad1 PF02144.11 EIW85499.1 - 2.8e-68 229.6 0.0 3.2e-68 229.4 0.0 1.0 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 DUF3246 PF11596.3 EIW85499.1 - 0.01 15.1 3.4 0.032 13.5 2.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3246) Mito_fiss_reg PF05308.6 EIW85499.1 - 0.13 11.5 0.4 0.27 10.5 0.3 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator Sterol-sensing PF12349.3 EIW85500.1 - 1.5e-33 115.4 7.2 2.7e-33 114.6 5.0 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EIW85500.1 - 1.7e-10 39.5 3.4 2.3e-10 39.0 2.4 1.1 1 0 0 1 1 1 1 Patched family DUF1517 PF07466.6 EIW85501.1 - 0.92 8.4 5.3 0.19 10.6 1.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1517) RNase_H PF00075.19 EIW85502.1 - 1.2e-05 25.6 0.1 2.1e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 RNase H zf-RVT PF13966.1 EIW85502.1 - 0.0084 16.4 0.5 0.019 15.2 0.3 1.7 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase p450 PF00067.17 EIW85503.1 - 2.3e-64 217.6 0.0 2.9e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW85506.1 - 7.1e-63 212.7 0.0 8.5e-63 212.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.8 EIW85508.1 - 3.5e-16 59.4 0.1 4.2e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIW85508.1 - 7.1e-06 24.9 0.0 9.4e-06 24.5 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EIW85508.1 - 0.024 13.3 0.3 0.13 10.9 0.2 1.9 1 1 0 1 1 1 0 Carboxylesterase family Pyr_redox_3 PF13738.1 EIW85509.1 - 2e-17 63.9 0.0 3e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EIW85509.1 - 1.1e-15 56.9 0.1 5.5e-15 54.5 0.1 2.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EIW85509.1 - 9.3e-10 37.9 0.0 6.7e-08 31.8 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EIW85509.1 - 8.3e-08 32.1 0.0 2.7e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIW85509.1 - 0.021 13.7 0.1 0.4 9.5 0.1 2.3 1 1 1 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 EIW85509.1 - 0.099 11.7 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 EIW85509.1 - 0.13 12.6 2.2 0.14 12.5 0.1 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase O-FucT PF10250.4 EIW85510.1 - 2.7e-05 23.4 0.0 0.14 11.2 0.0 2.4 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase MIF PF01187.13 EIW85511.1 - 6.2e-09 35.9 0.0 7e-09 35.7 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) MIF PF01187.13 EIW85512.1 - 2.9e-13 49.8 0.0 3.1e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Tautomerase PF01361.16 EIW85512.1 - 0.12 12.0 0.0 2.4 7.8 0.0 2.1 2 0 0 2 2 2 0 Tautomerase enzyme MIF PF01187.13 EIW85513.1 - 2.2e-13 50.2 0.0 2.3e-13 50.2 0.0 1.0 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) DUF4449 PF14613.1 EIW85514.1 - 0.00058 19.8 0.0 0.0023 17.8 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) DUF2733 PF10813.3 EIW85514.1 - 0.11 12.1 0.5 0.23 11.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2733) Amidohydro_1 PF01979.15 EIW85515.1 - 7.5e-16 58.6 0.1 4.7e-09 36.3 0.0 2.6 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EIW85515.1 - 9.3e-13 48.8 0.3 9.3e-13 48.8 0.2 2.3 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_5 PF13594.1 EIW85515.1 - 1e-12 47.6 1.2 3.1e-12 46.1 0.5 2.2 2 0 0 2 2 2 1 Amidohydrolase PD40 PF07676.7 EIW85515.1 - 6.4e-08 32.1 0.8 3.2e-05 23.4 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat Amidohydro_3 PF07969.6 EIW85515.1 - 9.9e-08 31.6 0.4 0.0026 17.0 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Rpp20 PF12328.3 EIW85516.1 - 5.1e-05 22.9 0.0 0.057 13.0 0.0 2.3 1 1 1 2 2 2 2 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EIW85516.1 - 0.0021 17.6 0.0 0.0046 16.5 0.0 1.6 2 0 0 2 2 2 1 Alba DUF748 PF05359.6 EIW85516.1 - 0.0098 15.9 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF748) eRF1_2 PF03464.10 EIW85517.1 - 1.2e-45 155.1 0.1 2.2e-45 154.2 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EIW85517.1 - 8.5e-39 132.3 0.3 1.9e-38 131.2 0.2 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EIW85517.1 - 1.6e-26 92.4 0.0 3.3e-26 91.4 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 Phosducin PF02114.11 EIW85518.1 - 3e-07 29.4 0.0 5.5e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 Phosducin DUF3886 PF13025.1 EIW85518.1 - 0.016 15.1 2.1 0.051 13.5 1.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) GOLD_2 PF13897.1 EIW85518.1 - 5.4 7.2 9.2 0.35 11.0 0.9 2.1 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Ribonuclease_3 PF00636.21 EIW85519.1 - 1.7e-38 131.6 0.0 3.6e-19 69.3 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EIW85519.1 - 1.4e-26 92.9 0.1 4.4e-14 52.5 0.1 4.3 3 1 0 3 3 3 2 Ribonuclease-III-like DEAD PF00270.24 EIW85519.1 - 1.2e-16 60.6 0.0 2.4e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EIW85519.1 - 1.6e-15 57.4 0.0 4e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EIW85519.1 - 2.8e-14 52.7 0.0 8.3e-14 51.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 EIW85519.1 - 6.5e-10 38.6 0.0 2e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Dicer dimerisation domain SNF2_N PF00176.18 EIW85519.1 - 1.1e-08 34.1 0.0 1.9e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.1 EIW85519.1 - 0.066 13.3 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain WD40 PF00400.27 EIW85520.1 - 5.5e-05 22.8 0.8 0.053 13.4 0.0 4.4 5 0 0 5 5 5 1 WD domain, G-beta repeat Ras PF00071.17 EIW85521.1 - 7.7e-54 181.4 0.0 8.8e-54 181.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW85521.1 - 9.4e-16 58.3 0.0 1.3e-15 57.8 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW85521.1 - 6.7e-07 28.7 0.0 9.1e-07 28.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF1077 PF06417.7 EIW85522.1 - 2.6e-40 136.6 0.1 3e-40 136.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) RRM_1 PF00076.17 EIW85523.1 - 1e-31 108.3 0.0 5e-17 61.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW85523.1 - 2.5e-15 56.2 0.0 8.6e-07 28.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW85523.1 - 5.6e-10 38.9 0.0 0.00089 19.0 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Senescence PF06911.7 EIW85526.1 - 1.2e-15 57.6 6.3 1.6e-10 40.9 0.2 2.4 2 0 0 2 2 2 2 Senescence-associated protein F-box-like PF12937.2 EIW85527.1 - 0.0034 17.0 0.1 0.0034 17.0 0.1 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EIW85527.1 - 0.028 14.0 1.8 86 2.9 0.0 5.4 5 0 0 5 5 5 0 Leucine Rich repeats (2 copies) DNA_pol_A_exo1 PF01612.15 EIW85527.1 - 0.041 13.3 0.0 10 5.5 0.0 2.4 2 0 0 2 2 2 0 3'-5' exonuclease NPH3 PF03000.9 EIW85527.1 - 0.094 12.2 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 NPH3 family SYS1 PF09801.4 EIW85529.1 - 0.084 12.8 0.2 0.14 12.1 0.2 1.4 1 1 0 1 1 1 0 Integral membrane protein S linking to the trans Golgi network HTH_29 PF13551.1 EIW85531.1 - 1.1e-07 31.9 0.1 1.9e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EIW85531.1 - 0.00097 18.7 0.3 0.0032 17.0 0.1 2.1 2 0 0 2 2 2 1 Homeodomain-like domain DUF3452 PF11934.3 EIW85531.1 - 0.0081 15.4 0.0 0.021 14.1 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3452) M11L PF11099.3 EIW85531.1 - 0.035 13.8 0.0 0.058 13.1 0.0 1.5 1 0 0 1 1 1 0 Apoptosis regulator M11L like DUF2353 PF09789.4 EIW85531.1 - 0.055 12.7 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) HTH_7 PF02796.10 EIW85531.1 - 0.11 12.3 0.0 12 5.8 0.0 2.7 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase TPR_12 PF13424.1 EIW85532.1 - 0.043 13.7 3.5 10 6.1 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIW85532.1 - 0.091 12.7 4.8 5.6 7.1 0.4 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EIW85532.1 - 0.095 12.5 0.1 4.6 7.1 0.0 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Cut8_N PF14482.1 EIW85533.1 - 0.026 14.5 0.4 0.09 12.7 0.3 1.9 1 0 0 1 1 1 0 Cut8 proteasome-binding domain Pox_RNA_Pol_19 PF05320.7 EIW85533.1 - 0.25 11.0 1.6 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit FMN_dh PF01070.13 EIW85534.1 - 2.1e-104 349.2 0.0 2.6e-104 348.8 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EIW85534.1 - 1.3e-05 24.2 0.6 0.00025 20.0 0.1 2.5 1 1 2 3 3 3 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EIW85534.1 - 1.8e-05 24.0 0.9 3e-05 23.3 0.6 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 EIW85534.1 - 2e-05 23.8 0.7 0.031 13.3 0.1 2.2 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 EIW85534.1 - 0.00027 19.9 0.2 0.00047 19.1 0.2 1.5 1 1 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EIW85534.1 - 0.0015 17.8 0.2 0.089 12.0 0.0 2.2 1 1 1 2 2 2 1 Histidine biosynthesis protein IGPS PF00218.16 EIW85534.1 - 0.017 14.1 0.0 0.028 13.4 0.0 1.2 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase PcrB PF01884.12 EIW85534.1 - 0.023 13.9 0.3 1.9 7.6 0.0 2.2 1 1 1 2 2 2 0 PcrB family Abhydrolase_6 PF12697.2 EIW85535.1 - 2.4e-14 53.7 0.3 1.3e-13 51.4 0.2 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW85535.1 - 4.2e-05 23.2 0.0 0.007 15.9 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EIW85535.1 - 0.00083 19.1 0.1 0.0037 17.0 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase Abhydrolase_5 PF12695.2 EIW85535.1 - 0.0014 18.4 0.1 0.033 13.9 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family MIF4G PF02854.14 EIW85536.1 - 9.1e-27 93.8 3.9 8.6e-26 90.6 0.1 2.4 2 1 0 2 2 2 2 MIF4G domain MA3 PF02847.12 EIW85536.1 - 1.6e-22 79.3 0.2 4.1e-22 78.0 0.1 1.8 1 0 0 1 1 1 1 MA3 domain Lactamase_B PF00753.22 EIW85537.1 - 6.2e-14 52.1 0.8 2.2e-13 50.3 0.6 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EIW85537.1 - 1.3e-05 24.8 0.1 1.7e-05 24.4 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Ras PF00071.17 EIW85538.1 - 6.4e-63 210.9 0.3 7.6e-63 210.7 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW85538.1 - 7.9e-21 74.7 0.0 1.3e-20 74.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW85538.1 - 6e-13 48.4 0.1 7.8e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EIW85538.1 - 8.6e-08 32.1 0.1 1.4e-07 31.4 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIW85538.1 - 1.2e-05 24.7 0.2 4.5e-05 22.9 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EIW85538.1 - 4.1e-05 23.7 0.0 0.00015 21.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 EIW85538.1 - 0.00041 19.5 0.1 0.00072 18.7 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_15 PF13175.1 EIW85538.1 - 0.0018 17.3 0.1 0.0024 16.9 0.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EIW85538.1 - 0.0034 16.6 0.0 0.0071 15.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EIW85538.1 - 0.0067 15.6 0.0 0.011 14.9 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EIW85538.1 - 0.0075 15.7 0.0 0.021 14.3 0.0 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EIW85538.1 - 0.014 15.2 0.0 0.035 14.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIW85538.1 - 0.024 14.6 0.2 0.052 13.5 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EIW85538.1 - 0.03 14.6 0.1 0.044 14.0 0.0 1.5 1 1 0 1 1 1 0 ABC transporter AAA_24 PF13479.1 EIW85538.1 - 0.045 13.3 0.1 0.073 12.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EIW85538.1 - 0.052 12.8 0.3 0.11 11.7 0.2 1.7 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.1 EIW85538.1 - 0.1 12.1 0.0 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EIW85538.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF1128 PF06569.6 EIW85538.1 - 0.12 12.0 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) DUF718 PF05336.8 EIW85539.1 - 1.3e-30 105.3 0.2 1.4e-30 105.1 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF718) VCBS PF13517.1 EIW85541.1 - 1.3e-29 102.2 12.5 1.9e-08 34.4 0.2 5.7 4 1 1 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EIW85541.1 - 1.5e-12 46.7 20.4 0.16 11.6 0.1 7.5 7 0 0 7 7 7 6 FG-GAP repeat TcdB_toxin_midN PF12256.3 EIW85541.1 - 0.0092 15.4 11.1 0.29 10.5 0.1 5.8 4 1 4 8 8 8 2 Insecticide toxin TcdB middle/N-terminal region Cytochrome_C7 PF14522.1 EIW85543.1 - 1.3 8.7 7.9 0.25 10.9 2.3 2.0 2 1 0 2 2 2 0 Cytochrome c7 Cytochrom_c3_2 PF14537.1 EIW85543.1 - 2.7 8.3 7.8 4.4 7.7 5.4 1.5 1 1 0 1 1 1 0 Cytochrome c3 Peptidase_M50B PF13398.1 EIW85546.1 - 2.3e-53 180.5 19.5 3.3e-53 180.0 13.5 1.2 1 0 0 1 1 1 1 Peptidase M50B-like DUF3040 PF11239.3 EIW85546.1 - 0.016 15.2 8.6 1 9.4 0.0 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3040) DAGK_prokar PF01219.14 EIW85546.1 - 0.39 10.3 7.6 4.3 6.9 1.8 2.8 2 0 0 2 2 2 0 Prokaryotic diacylglycerol kinase Wzy_C PF04932.10 EIW85546.1 - 1.3 8.7 15.3 3.6 7.3 6.4 3.0 2 1 0 2 2 2 0 O-Antigen ligase V_ATPase_I PF01496.14 EIW85547.1 - 1.2e-273 909.5 0.0 1.5e-273 909.2 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family SlyX PF04102.7 EIW85547.1 - 0.0037 17.6 0.8 0.017 15.4 0.3 2.2 2 0 0 2 2 2 1 SlyX Clusterin PF01093.12 EIW85547.1 - 0.035 12.9 0.3 0.055 12.2 0.2 1.2 1 0 0 1 1 1 0 Clusterin GerPC PF10737.4 EIW85547.1 - 0.052 13.3 0.7 0.89 9.3 0.1 2.3 1 1 1 2 2 2 0 Spore germination protein GerPC ABC_tran PF00005.22 EIW85548.1 - 8.3e-44 149.2 0.1 6.9e-21 74.9 0.0 3.7 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EIW85548.1 - 6.3e-13 49.3 7.8 5.3e-05 23.3 0.8 4.4 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 EIW85548.1 - 6.6e-12 45.1 1.7 0.0056 15.9 0.0 4.2 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EIW85548.1 - 1.7e-08 33.8 0.2 0.007 15.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EIW85548.1 - 4.6e-07 30.6 0.1 0.0026 18.5 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EIW85548.1 - 1.6e-06 28.3 0.0 0.011 15.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain DUF87 PF01935.12 EIW85548.1 - 5.3e-06 26.4 0.0 0.0034 17.2 0.0 3.0 2 0 0 2 2 2 1 Domain of unknown function DUF87 Miro PF08477.8 EIW85548.1 - 8e-06 26.3 0.0 0.12 12.8 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein SbcCD_C PF13558.1 EIW85548.1 - 1.2e-05 25.1 0.0 0.076 12.9 0.0 3.4 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EIW85548.1 - 1.7e-05 24.4 2.3 0.037 13.4 0.0 3.6 3 1 0 3 3 3 2 AAA-like domain NACHT PF05729.7 EIW85548.1 - 2.2e-05 24.1 0.1 0.26 10.9 0.0 2.6 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.18 EIW85548.1 - 4.8e-05 23.2 0.0 0.26 11.2 0.0 3.2 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 EIW85548.1 - 4.9e-05 23.6 0.4 0.061 13.6 0.1 2.7 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EIW85548.1 - 5.7e-05 22.8 0.1 0.38 10.4 0.0 3.4 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EIW85548.1 - 7.4e-05 22.8 0.0 0.38 10.9 0.0 3.0 3 0 0 3 3 2 2 RNA helicase DUF258 PF03193.11 EIW85548.1 - 8.5e-05 21.7 0.0 0.16 11.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 EIW85548.1 - 0.0001 22.2 0.4 0.5 10.2 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.1 EIW85548.1 - 0.00012 21.3 1.1 1.4 7.8 0.1 3.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_23 PF13476.1 EIW85548.1 - 0.00012 22.4 8.9 0.028 14.7 0.0 3.8 4 0 0 4 4 4 2 AAA domain Chromo PF00385.19 EIW85548.1 - 0.0002 20.9 0.2 0.00051 19.6 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain AAA PF00004.24 EIW85548.1 - 0.00032 20.8 0.0 2 8.6 0.0 3.5 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EIW85548.1 - 0.0005 19.5 0.0 1.3 8.3 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.1 EIW85548.1 - 0.0011 18.9 0.0 1.5 8.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EIW85548.1 - 0.0013 17.6 1.5 0.34 9.6 0.0 2.8 3 0 0 3 3 3 1 ArgK protein HEAT_2 PF13646.1 EIW85548.1 - 0.0017 18.5 16.4 0.94 9.7 8.5 4.0 2 1 1 3 3 2 2 HEAT repeats Adaptin_N PF01602.15 EIW85548.1 - 0.002 16.5 0.1 0.0045 15.3 0.1 1.5 1 1 0 1 1 1 1 Adaptin N terminal region FtsK_SpoIIIE PF01580.13 EIW85548.1 - 0.0037 16.7 0.2 0.85 9.0 0.0 3.0 3 0 0 3 3 3 1 FtsK/SpoIIIE family HEAT PF02985.17 EIW85548.1 - 0.0057 16.6 8.6 0.044 13.8 0.1 5.0 5 0 0 5 5 5 1 HEAT repeat Dynamin_N PF00350.18 EIW85548.1 - 0.0097 15.7 1.5 0.15 11.9 0.0 2.7 3 0 0 3 3 2 1 Dynamin family DUF815 PF05673.8 EIW85548.1 - 0.013 14.4 0.2 2.2 7.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 EIW85548.1 - 0.02 14.8 0.2 4 7.3 0.1 3.3 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EIW85548.1 - 0.038 13.9 11.6 0.073 13.0 0.3 4.4 3 2 0 3 3 3 0 AAA ATPase domain KAP_NTPase PF07693.9 EIW85548.1 - 0.063 12.2 0.6 0.36 9.7 0.0 2.4 3 0 0 3 3 3 0 KAP family P-loop domain FERM_N PF09379.5 EIW85548.1 - 0.066 13.2 0.1 0.2 11.7 0.0 1.8 1 0 0 1 1 1 0 FERM N-terminal domain ATP-synt_ab PF00006.20 EIW85548.1 - 0.074 12.5 1.1 4 6.8 0.0 3.8 4 1 0 4 4 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Cohesin_HEAT PF12765.2 EIW85548.1 - 0.079 12.9 0.1 0.25 11.3 0.0 2.0 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.1 EIW85548.1 - 0.12 12.9 18.6 2.8 8.5 2.0 5.7 4 2 3 7 7 6 0 HEAT-like repeat cobW PF02492.14 EIW85548.1 - 0.22 10.9 2.8 12 5.3 0.1 3.4 4 0 0 4 4 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EIW85548.1 - 1.1 8.9 5.3 14 5.3 0.1 4.0 5 0 0 5 5 4 0 AAA domain (dynein-related subfamily) AAA_13 PF13166.1 EIW85548.1 - 5.2 5.4 11.8 0.75 8.1 0.0 2.9 3 1 0 3 3 2 0 AAA domain NAD_binding_10 PF13460.1 EIW85549.1 - 2.1e-06 27.8 0.2 2.4e-06 27.6 0.1 1.0 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW85549.1 - 0.0001 21.8 0.0 0.00011 21.6 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EIW85549.1 - 0.0002 20.4 0.1 0.00023 20.2 0.1 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 EIW85549.1 - 0.0035 16.6 0.1 0.21 10.8 0.0 2.0 1 1 1 2 2 2 1 NmrA-like family Semialdhyde_dh PF01118.19 EIW85549.1 - 0.0041 17.4 0.1 0.0065 16.7 0.0 1.3 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EIW85549.1 - 0.0068 15.1 0.0 0.0078 14.9 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EIW85549.1 - 0.013 14.4 0.0 0.016 14.1 0.0 1.0 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_4 PF07993.7 EIW85549.1 - 0.026 13.4 0.0 0.031 13.2 0.0 1.2 1 1 0 1 1 1 0 Male sterility protein NAD_binding_3 PF03447.11 EIW85549.1 - 0.037 14.4 0.0 0.048 14.0 0.0 1.1 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF2201 PF09967.4 EIW85549.1 - 0.051 13.5 0.1 0.062 13.3 0.1 1.2 1 0 0 1 1 1 0 VWA-like domain (DUF2201) Polysacc_synt_2 PF02719.10 EIW85549.1 - 0.1 11.4 0.0 0.15 10.9 0.0 1.3 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 EIW85549.1 - 0.12 12.2 0.0 0.16 11.8 0.0 1.3 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 EIW85549.1 - 0.18 11.6 0.5 0.47 10.3 0.4 1.6 1 1 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.1 EIW85550.1 - 6.1e-08 32.8 0.0 9.5e-06 25.7 0.0 2.4 1 1 0 1 1 1 1 NADH(P)-binding F-box-like PF12937.2 EIW85551.1 - 0.00023 20.8 0.0 0.00079 19.1 0.0 2.0 1 1 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EIW85551.1 - 0.00078 19.0 0.3 1.9 8.2 0.1 3.6 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW85551.1 - 0.0031 17.2 0.3 7.1 6.4 0.2 4.0 3 1 1 4 4 4 1 Leucine rich repeat LRR_7 PF13504.1 EIW85551.1 - 0.075 13.2 0.9 56 4.6 0.0 3.8 3 0 0 3 3 3 0 Leucine rich repeat Histone PF00125.19 EIW85552.1 - 3.8e-30 103.8 0.6 6.2e-30 103.1 0.4 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIW85552.1 - 4e-05 23.7 0.0 6.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EIW85552.1 - 0.0061 16.6 0.7 0.01 15.8 0.0 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EIW85552.1 - 0.024 13.8 1.2 0.028 13.6 0.9 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T DUF2360 PF10152.4 EIW85552.1 - 0.08 13.2 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Bromo_TP PF07524.8 EIW85552.1 - 0.14 11.8 0.5 0.22 11.2 0.1 1.6 2 0 0 2 2 2 0 Bromodomain associated DDOST_48kD PF03345.9 EIW85554.1 - 1e-94 317.5 0.0 1.3e-94 317.1 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Cupredoxin_1 PF13473.1 EIW85554.1 - 0.15 11.9 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Cupredoxin-like domain ADK PF00406.17 EIW85555.1 - 1.1e-58 197.3 0.0 1.4e-58 197.0 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EIW85555.1 - 4.9e-14 51.6 0.0 9.4e-14 50.7 0.0 1.5 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EIW85555.1 - 0.00042 21.1 0.1 0.00086 20.1 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW85555.1 - 0.004 17.0 0.0 0.008 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIW85555.1 - 0.012 14.6 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EIW85555.1 - 0.017 15.3 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NmrA PF05368.8 EIW85557.1 - 1.7e-19 70.0 0.0 1.9e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIW85557.1 - 2.7e-13 50.3 0.2 3.7e-13 49.9 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW85557.1 - 2.6e-08 33.5 0.0 3.6e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIW85557.1 - 1.3e-05 24.2 0.1 2.1e-05 23.5 0.1 1.4 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EIW85557.1 - 0.00016 21.6 0.8 0.00032 20.6 0.6 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW85557.1 - 0.004 16.8 0.1 0.0065 16.1 0.1 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EIW85557.1 - 0.058 12.3 0.0 0.082 11.8 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein F420_oxidored PF03807.12 EIW85557.1 - 0.065 13.6 0.9 0.14 12.5 0.6 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EIW85557.1 - 0.1 12.6 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 EIW85558.1 - 7.8e-17 61.3 0.0 1e-16 60.9 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIW85558.1 - 7.4e-09 35.8 0.2 9.8e-09 35.4 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW85558.1 - 3.2e-06 26.7 0.5 4.3e-06 26.3 0.4 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIW85558.1 - 0.001 18.0 0.2 0.0015 17.4 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DapB_N PF01113.15 EIW85558.1 - 0.021 14.7 1.1 0.18 11.6 0.8 2.1 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus HypD PF01924.11 EIW85558.1 - 0.093 11.4 0.1 0.12 11.0 0.1 1.1 1 0 0 1 1 1 0 Hydrogenase formation hypA family Histone PF00125.19 EIW85561.1 - 3.8e-30 103.8 0.6 6.1e-30 103.1 0.4 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIW85561.1 - 3.9e-05 23.7 0.0 6.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EIW85561.1 - 0.0087 16.1 1.7 0.0099 15.9 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EIW85561.1 - 0.026 13.7 1.2 0.03 13.5 0.9 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Bromo_TP PF07524.8 EIW85561.1 - 0.12 12.0 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated WD40 PF00400.27 EIW85562.1 - 3.6e-58 191.5 12.5 1.7e-10 40.3 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EIW85562.1 - 5.5e-08 32.7 0.5 8e-05 22.4 0.0 2.3 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EIW85562.1 - 0.0013 17.6 0.0 0.0017 17.2 0.0 1.1 1 0 0 1 1 1 1 Coatomer WD associated region Nucleoporin_N PF08801.6 EIW85562.1 - 0.0023 16.7 0.1 3.5 6.2 0.0 3.1 1 1 2 3 3 3 2 Nup133 N terminal like Apc4_WD40 PF12894.2 EIW85562.1 - 0.003 17.0 0.0 0.57 9.7 0.0 3.2 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.7 EIW85562.1 - 0.0034 15.2 0.0 0.0056 14.5 0.0 1.3 1 0 0 1 1 1 1 IKI3 family Det1 PF09737.4 EIW85562.1 - 0.025 13.3 0.0 0.039 12.7 0.0 1.1 1 0 0 1 1 1 0 De-etiolated protein 1 Det1 Nbas_N PF15492.1 EIW85562.1 - 0.073 12.1 0.2 5.6 5.9 0.0 2.9 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal DUF3312 PF11768.3 EIW85562.1 - 0.27 9.4 0.0 0.89 7.7 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Methyltransf_25 PF13649.1 EIW85563.1 - 8e-06 26.1 0.1 5.4e-05 23.4 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain CBM_21 PF03370.8 EIW85564.1 - 3.4e-27 94.6 0.0 6.2e-27 93.8 0.0 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit CBM_25 PF03423.8 EIW85564.1 - 0.24 11.5 0.4 0.82 9.7 0.3 1.9 1 1 0 1 1 1 0 Carbohydrate binding domain (family 25) Glyco_hydro_76 PF03663.9 EIW85565.1 - 2.2e-16 60.2 24.2 1.6e-15 57.4 16.8 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 NmrA PF05368.8 EIW85566.1 - 1.3e-19 70.3 0.0 1.6e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIW85566.1 - 5.2e-06 26.6 0.1 6.8e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW85566.1 - 0.00011 21.7 0.1 0.00016 21.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIW85566.1 - 0.0029 16.5 0.1 0.0047 15.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EIW85566.1 - 0.0045 15.9 0.0 0.0061 15.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EIW85566.1 - 0.013 15.3 0.2 0.025 14.4 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 EIW85566.1 - 0.02 14.5 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.14 EIW85566.1 - 0.026 13.2 0.1 0.036 12.7 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EIW85566.1 - 0.044 13.7 0.3 0.46 10.4 0.2 2.1 1 1 0 1 1 1 0 TrkA-N domain GFO_IDH_MocA PF01408.17 EIW85566.1 - 0.049 14.1 0.1 0.095 13.2 0.1 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EIW85566.1 - 0.053 13.8 0.1 0.086 13.1 0.1 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EIW85566.1 - 0.081 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.8 EIW85567.1 - 1.8e-18 66.6 0.0 2.3e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIW85567.1 - 2.2e-07 31.0 0.2 3.4e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EIW85567.1 - 0.00017 20.6 0.0 0.00024 20.2 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EIW85567.1 - 0.00065 19.2 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EIW85567.1 - 0.0027 17.6 0.3 0.0042 17.0 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW85567.1 - 0.0095 15.6 0.3 0.027 14.1 0.2 1.8 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EIW85567.1 - 0.015 14.0 0.0 0.045 12.4 0.0 1.7 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EIW85567.1 - 0.03 13.2 0.0 0.05 12.4 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EIW85567.1 - 0.055 13.5 0.1 0.76 9.8 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.7 EIW85567.1 - 0.16 10.9 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Abhydrolase_6 PF12697.2 EIW85568.1 - 3.9e-27 95.6 0.0 4.8e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW85568.1 - 6.4e-10 38.9 0.0 1.1e-09 38.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW85568.1 - 0.00021 20.9 0.0 0.39 10.2 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EIW85568.1 - 0.0022 17.7 0.1 0.011 15.5 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase UPF0227 PF05728.7 EIW85568.1 - 0.086 12.5 0.0 0.59 9.8 0.0 2.1 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0227) Lig_chan PF00060.21 EIW85569.1 - 2 8.1 7.5 0.32 10.7 2.0 2.0 3 0 0 3 3 3 0 Ligand-gated ion channel ABC2_membrane PF01061.19 EIW85570.1 - 2.7e-34 118.1 19.1 2.7e-34 118.1 13.2 2.2 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EIW85570.1 - 3.5e-24 85.6 0.0 5.5e-24 85.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EIW85570.1 - 0.0014 17.8 1.4 0.0026 16.9 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 EIW85570.1 - 0.0083 16.1 0.0 1.1 9.1 0.1 2.6 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EIW85570.1 - 0.012 15.6 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 EIW85570.1 - 0.014 14.8 0.1 0.031 13.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EIW85570.1 - 0.016 15.3 0.1 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIW85570.1 - 0.017 14.6 0.1 0.04 13.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain hEGF PF12661.2 EIW85570.1 - 0.042 13.9 16.8 0.31 11.1 3.4 2.9 2 0 0 2 2 2 0 Human growth factor-like EGF AAA_28 PF13521.1 EIW85570.1 - 0.044 13.7 0.2 0.076 12.9 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EIW85570.1 - 0.054 14.3 0.6 0.11 13.3 0.4 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EIW85570.1 - 0.088 12.3 0.1 0.15 11.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EIW85570.1 - 0.12 12.1 0.4 0.24 11.2 0.2 1.4 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EIW85570.1 - 0.17 11.5 0.1 0.33 10.5 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ABC2_membrane_3 PF12698.2 EIW85570.1 - 0.17 10.8 31.6 0.38 9.7 20.8 2.3 1 1 1 2 2 2 0 ABC-2 family transporter protein AAA PF00004.24 EIW85570.1 - 0.19 11.9 0.1 0.44 10.7 0.1 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EIW85570.1 - 0.19 11.3 0.1 0.32 10.6 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.2 EIW85570.1 - 0.22 10.9 0.3 0.33 10.3 0.2 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 EIW85570.1 - 0.34 11.2 0.6 0.61 10.3 0.4 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EIW85570.1 - 0.47 10.7 0.0 0.77 10.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain COX17 PF05051.8 EIW85571.1 - 6e-21 74.2 1.8 7.5e-21 73.9 1.3 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 EIW85571.1 - 0.51 10.1 2.8 0.69 9.7 0.0 2.0 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Cerato-platanin PF07249.7 EIW85572.1 - 7.3e-42 142.1 4.8 8.7e-42 141.8 3.3 1.1 1 0 0 1 1 1 1 Cerato-platanin Cerato-platanin PF07249.7 EIW85573.1 - 3.3e-45 152.9 3.6 3.9e-45 152.7 2.5 1.0 1 0 0 1 1 1 1 Cerato-platanin Glyco_hydro_45 PF02015.11 EIW85573.1 - 0.018 15.1 1.4 0.02 14.9 1.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 45 Cerato-platanin PF07249.7 EIW85574.1 - 4.8e-31 107.2 0.3 7.3e-31 106.6 0.2 1.2 1 0 0 1 1 1 1 Cerato-platanin NmrA PF05368.8 EIW85575.1 - 1.2e-17 64.0 0.0 1.5e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIW85575.1 - 7.6e-11 42.3 0.1 2e-10 40.9 0.4 1.4 2 0 0 2 2 2 1 NADH(P)-binding Saccharop_dh PF03435.13 EIW85575.1 - 8.1e-05 21.7 0.1 0.00011 21.3 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EIW85575.1 - 0.0008 18.9 0.1 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EIW85575.1 - 0.033 14.4 0.1 0.055 13.7 0.1 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 EIW85575.1 - 0.085 12.5 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 KR domain 3Beta_HSD PF01073.14 EIW85575.1 - 0.12 11.0 0.0 0.32 9.6 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_19 PF04672.7 EIW85575.1 - 0.12 11.5 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl methyltransferase NmrA PF05368.8 EIW85576.1 - 1.2e-20 73.8 0.0 1.5e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIW85576.1 - 4.1e-08 33.4 0.4 6.1e-08 32.8 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EIW85576.1 - 0.017 14.7 0.0 0.029 14.0 0.0 1.3 1 0 0 1 1 1 0 KR domain Epimerase PF01370.16 EIW85576.1 - 0.023 14.1 0.1 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EIW85576.1 - 0.035 12.9 0.0 0.07 12.0 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EIW85576.1 - 0.094 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.18 EIW85576.1 - 0.098 12.4 2.5 0.23 11.2 1.7 1.7 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 EIW85576.1 - 0.11 11.4 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.8 EIW85577.1 - 4.4e-20 71.9 0.0 5.6e-20 71.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIW85577.1 - 8.6e-06 25.8 0.5 1.5e-05 25.1 0.4 1.3 1 0 0 1 1 1 1 NADH(P)-binding CPSase_L_chain PF00289.17 EIW85577.1 - 0.0002 21.4 0.0 0.00034 20.6 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Epimerase PF01370.16 EIW85577.1 - 0.029 13.7 0.2 0.044 13.2 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 EIW85577.1 - 0.034 13.9 1.0 0.058 13.2 0.3 1.5 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ThiF PF00899.16 EIW85577.1 - 0.6 9.9 2.3 0.83 9.4 1.3 1.6 1 1 0 1 1 1 0 ThiF family NmrA PF05368.8 EIW85578.1 - 5.1e-19 68.4 0.0 6.4e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIW85578.1 - 2.3e-11 44.0 0.4 2.9e-11 43.7 0.3 1.2 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EIW85578.1 - 3.1e-05 23.1 0.3 4.1e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EIW85578.1 - 0.00012 21.5 0.1 0.00017 21.0 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GARS_N PF02844.10 EIW85578.1 - 0.00013 22.3 0.2 0.00019 21.8 0.1 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain F420_oxidored PF03807.12 EIW85578.1 - 0.00098 19.5 0.3 0.0023 18.3 0.2 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 EIW85578.1 - 0.0067 16.1 0.2 0.012 15.3 0.2 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EIW85578.1 - 0.0078 14.9 0.0 0.019 13.6 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EIW85578.1 - 0.015 15.5 0.2 0.024 14.9 0.1 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 EIW85578.1 - 0.03 14.7 0.8 2.1 8.7 0.1 2.3 1 1 1 2 2 2 0 Homoserine dehydrogenase, NAD binding domain CbiJ PF02571.9 EIW85578.1 - 0.036 13.4 0.0 0.042 13.1 0.0 1.2 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK NAD_binding_4 PF07993.7 EIW85578.1 - 0.038 12.9 0.1 0.071 12.0 0.0 1.5 2 0 0 2 2 2 0 Male sterility protein CPSase_L_chain PF00289.17 EIW85578.1 - 0.056 13.5 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, N-terminal domain GFO_IDH_MocA PF01408.17 EIW85578.1 - 0.059 13.8 0.2 0.092 13.2 0.2 1.3 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.15 EIW85578.1 - 0.064 13.3 0.1 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase dTMP_synthase PF02593.9 EIW85578.1 - 0.14 11.4 0.0 0.18 11.0 0.0 1.2 1 0 0 1 1 1 0 Thymidylate synthase NAD_binding_10 PF13460.1 EIW85579.1 - 1e-05 25.6 0.0 0.12 12.3 0.0 2.7 2 1 0 2 2 2 2 NADH(P)-binding Glyoxalase_3 PF13468.1 EIW85580.1 - 4.8e-29 101.4 0.0 7.5e-29 100.8 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EIW85580.1 - 0.032 14.2 0.0 2.5 8.1 0.0 2.7 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Asp PF00026.18 EIW85581.1 - 5.3e-75 252.6 9.2 6.3e-75 252.3 6.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW85581.1 - 0.00046 20.1 1.1 0.0053 16.7 0.6 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIW85581.1 - 0.0006 19.3 0.2 0.014 14.9 0.0 2.2 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal MFS_1 PF07690.11 EIW85582.1 - 5.8e-44 150.2 24.6 5.8e-44 150.2 17.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW85582.1 - 2.2e-20 72.6 5.0 2.2e-20 72.6 3.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EIW85582.1 - 0.19 9.9 9.4 0.017 13.3 3.0 1.7 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) Glycos_transf_1 PF00534.15 EIW85584.1 - 7.1e-23 80.8 0.0 1.6e-21 76.5 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EIW85584.1 - 4.4e-14 52.5 0.1 8.3e-14 51.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EIW85584.1 - 3.8e-11 43.4 0.1 3.8e-09 36.8 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 EIW85584.1 - 2.1e-06 27.9 0.0 5.4e-06 26.5 0.0 1.7 1 1 1 2 2 2 1 Glycosyl transferases group 1 DUF1145 PF06611.7 EIW85584.1 - 0.021 14.4 0.0 0.06 12.9 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1145) Glyco_trans_1_2 PF13524.1 EIW85584.1 - 0.082 13.1 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 Cerato-platanin PF07249.7 EIW85585.1 - 2.4e-48 163.0 3.8 2.8e-48 162.8 2.6 1.0 1 0 0 1 1 1 1 Cerato-platanin Glyco_hydro_45 PF02015.11 EIW85585.1 - 0.046 13.8 1.2 0.056 13.5 0.9 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 45 F-box-like PF12937.2 EIW85586.1 - 0.051 13.3 0.2 0.32 10.7 0.1 2.4 2 0 0 2 2 2 0 F-box-like Sugar_tr PF00083.19 EIW85587.1 - 9.4e-20 70.6 20.6 1.1e-15 57.2 3.5 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EIW85587.1 - 6.9e-11 41.4 38.4 2e-10 39.9 16.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.2 EIW85588.1 - 9.8e-08 31.6 0.0 2.8e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EIW85588.1 - 0.015 15.0 3.1 1.5 8.6 0.1 4.0 4 0 0 4 4 4 0 Leucine rich repeat F-box PF00646.28 EIW85588.1 - 0.024 14.2 2.4 0.92 9.2 0.1 3.4 3 0 0 3 3 3 0 F-box domain DUF1691 PF07950.6 EIW85589.1 - 1e-05 25.3 3.4 0.00031 20.6 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) HMG_box PF00505.14 EIW85590.1 - 1.4e-08 34.8 5.7 9.8e-07 28.9 3.9 2.3 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIW85590.1 - 0.0044 17.3 0.6 0.0074 16.6 0.4 1.4 1 0 0 1 1 1 1 HMG-box domain F-box-like PF12937.2 EIW85591.1 - 0.00023 20.8 0.1 0.00023 20.8 0.1 3.5 4 1 0 4 4 4 1 F-box-like Methyltransf_31 PF13847.1 EIW85592.1 - 9.5e-17 60.9 0.0 1.2e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW85592.1 - 1.8e-16 60.2 0.3 3.3e-16 59.4 0.2 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW85592.1 - 8.8e-16 58.1 0.0 1.5e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW85592.1 - 1.3e-15 57.6 0.0 2.4e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW85592.1 - 7.7e-13 48.9 0.0 1.4e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW85592.1 - 5.8e-12 45.8 0.1 1.3e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW85592.1 - 4.8e-08 32.5 0.0 8.3e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EIW85592.1 - 9.9e-08 32.0 0.0 2.1e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW85592.1 - 3.6e-07 29.5 0.0 5.2e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EIW85592.1 - 6.7e-07 28.6 0.0 1e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 EIW85592.1 - 8.2e-05 22.3 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EIW85592.1 - 0.00021 21.3 0.0 0.00034 20.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase RrnaAD PF00398.15 EIW85592.1 - 0.00097 18.2 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase FmrO PF07091.6 EIW85592.1 - 0.004 16.2 0.1 0.0058 15.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) PrmA PF06325.8 EIW85592.1 - 0.0088 15.1 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.6 EIW85592.1 - 0.0094 15.3 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) TPMT PF05724.6 EIW85592.1 - 0.015 14.6 0.0 0.15 11.4 0.0 2.1 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_24 PF13578.1 EIW85592.1 - 0.02 15.7 0.4 0.066 14.0 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain DREV PF05219.7 EIW85592.1 - 0.15 10.8 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_23 PF13489.1 EIW85593.1 - 1.2e-16 60.8 0.0 1.5e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW85593.1 - 9.2e-15 54.9 0.0 1.6e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW85593.1 - 4.4e-13 49.0 0.0 6.5e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW85593.1 - 4.2e-12 46.6 0.1 9.2e-12 45.5 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW85593.1 - 2.4e-11 43.9 0.0 4.9e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW85593.1 - 4e-08 33.5 0.0 7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW85593.1 - 1.6e-06 28.1 0.0 3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW85593.1 - 4.2e-06 26.2 0.0 7.7e-06 25.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 EIW85593.1 - 9.4e-06 25.7 0.0 1.1e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EIW85593.1 - 4.2e-05 22.7 0.0 6.5e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EIW85593.1 - 0.00023 20.8 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EIW85593.1 - 0.0036 16.4 0.0 0.0047 16.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 EIW85593.1 - 0.023 13.7 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) DUF3113 PF11310.3 EIW85593.1 - 0.13 11.9 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) IMS PF00817.15 EIW85594.1 - 8.4e-41 139.2 0.0 3.7e-40 137.1 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EIW85594.1 - 1.8e-14 53.7 0.2 1.9e-13 50.4 0.0 2.6 3 0 0 3 3 3 1 impB/mucB/samB family C-terminal domain PTCB-BRCT PF12738.2 EIW85594.1 - 8.9e-05 22.2 0.0 0.00019 21.2 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EIW85594.1 - 0.00011 22.2 0.0 0.00022 21.3 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.3 EIW85594.1 - 0.00031 20.6 0.0 0.00087 19.2 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif DUF1805 PF08827.6 EIW85594.1 - 0.049 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1805) DUF4414 PF14377.1 EIW85594.1 - 0.14 12.1 5.1 0.49 10.3 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4414) F-box-like PF12937.2 EIW85595.1 - 5.9e-07 29.1 0.6 1.3e-06 28.0 0.4 1.7 1 0 0 1 1 1 1 F-box-like HAD_2 PF13419.1 EIW85595.1 - 0.036 14.3 0.0 0.71 10.0 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase F-box PF00646.28 EIW85595.1 - 0.065 12.9 1.1 0.5 10.0 0.7 2.4 1 1 0 1 1 1 0 F-box domain GspH PF12019.3 EIW85596.1 - 0.35 11.0 5.5 6.6 6.9 0.9 3.3 1 1 1 2 2 2 0 Type II transport protein GspH Cna_B PF05738.8 EIW85596.1 - 0.79 9.5 4.4 13 5.6 0.1 4.0 5 0 0 5 5 5 0 Cna protein B-type domain Calcipressin PF04847.7 EIW85597.1 - 4.6e-34 117.6 0.0 5.2e-34 117.4 0.0 1.1 1 0 0 1 1 1 1 Calcipressin Nup35_RRM_2 PF14605.1 EIW85597.1 - 0.087 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 EIW85597.1 - 0.092 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1014 PF06244.7 EIW85598.1 - 1.4e-25 89.9 5.3 1.4e-25 89.9 3.7 3.2 2 2 0 2 2 2 1 Protein of unknown function (DUF1014) DUF2639 PF11121.3 EIW85598.1 - 0.043 13.3 3.3 6.9 6.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2639) zf-HC5HC2H_2 PF13832.1 EIW85600.1 - 0.0019 18.1 0.5 0.0054 16.7 0.3 1.8 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EIW85600.1 - 4.2 7.5 8.3 0.076 13.1 0.6 2.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-BED PF02892.10 EIW85602.1 - 0.17 11.6 1.1 0.49 10.2 0.7 1.7 1 0 0 1 1 1 0 BED zinc finger DUF4501 PF14946.1 EIW85603.1 - 0.4 10.1 1.8 0.71 9.3 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) F-box-like PF12937.2 EIW85608.1 - 2.1e-09 36.9 0.9 5.3e-09 35.6 0.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW85608.1 - 7.4e-05 22.2 2.9 0.00052 19.5 1.0 3.1 3 1 0 3 3 3 1 F-box domain NIL PF09383.5 EIW85608.1 - 0.037 13.6 0.0 0.43 10.1 0.0 2.3 2 0 0 2 2 2 0 NIL domain DUF4381 PF14316.1 EIW85609.1 - 0.0054 16.8 0.3 0.0095 16.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4381) GF_recep_IV PF14843.1 EIW85609.1 - 0.0065 16.0 21.1 0.0065 16.0 14.6 6.1 1 1 6 7 7 7 5 Growth factor receptor domain IV VSP PF03302.8 EIW85609.1 - 0.019 13.6 163.1 0.051 12.2 8.9 6.1 1 1 4 5 5 5 0 Giardia variant-specific surface protein cEGF PF12662.2 EIW85609.1 - 2.3 7.9 51.5 0.25 10.9 0.2 8.7 6 2 1 7 7 7 0 Complement Clr-like EGF-like PP2C PF00481.16 EIW85610.1 - 1.9e-18 66.7 0.0 6.7e-16 58.4 0.0 3.0 3 0 0 3 3 3 1 Protein phosphatase 2C F-box-like PF12937.2 EIW85610.1 - 8.1e-08 31.8 0.0 2.1e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 F-box-like PP2C_2 PF13672.1 EIW85610.1 - 1.1e-05 24.9 0.0 5.5e-05 22.6 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EIW85610.1 - 0.024 14.3 0.1 1.1 8.9 0.0 3.0 2 1 1 3 3 3 0 Stage II sporulation protein E (SpoIIE) F-box-like PF12937.2 EIW85611.1 - 1.3e-08 34.3 0.0 3.6e-08 33.0 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW85611.1 - 0.084 12.5 0.6 0.68 9.6 0.4 2.7 1 1 0 1 1 1 0 F-box domain Asp PF00026.18 EIW85612.1 - 6.8e-46 156.9 8.0 1.8e-45 155.5 5.6 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EIW85612.1 - 0.00054 20.4 2.9 0.3 11.6 0.3 2.6 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EIW85612.1 - 0.0073 16.2 0.2 0.033 14.1 0.1 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 EIW85612.1 - 0.017 14.9 0.1 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DDE_1 PF03184.14 EIW85612.1 - 0.061 12.4 0.0 0.099 11.7 0.0 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease TAXi_C PF14541.1 EIW85612.1 - 0.074 12.5 1.0 0.53 9.8 0.1 2.6 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal RCC1_2 PF13540.1 EIW85613.1 - 5.2e-11 41.8 20.9 3.7e-06 26.4 0.1 4.9 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EIW85613.1 - 6.1e-11 42.3 8.0 0.04 14.1 0.0 6.2 7 0 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.2 EIW85613.1 - 0.0017 18.0 0.6 0.0035 17.0 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIW85613.1 - 0.0032 17.0 0.1 0.0063 16.1 0.1 1.5 1 0 0 1 1 1 1 F-box domain DOPA_dioxygen PF08883.6 EIW85614.1 - 3.5e-29 100.9 0.0 5.3e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family Flp_N PF03930.9 EIW85614.1 - 0.1 12.3 0.1 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Recombinase Flp protein N-terminus Per1 PF04080.8 EIW85615.1 - 8.5e-93 310.6 0.7 1.2e-92 310.0 0.5 1.2 1 0 0 1 1 1 1 Per1-like Pribosyltran_N PF13793.1 EIW85617.1 - 1.6e-49 166.4 0.2 4.1e-46 155.4 0.0 3.0 2 1 1 3 3 3 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EIW85617.1 - 2.4e-39 135.0 1.7 1.9e-35 122.3 0.6 2.3 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EIW85617.1 - 2.3e-14 53.2 0.3 4.2e-13 49.1 0.2 2.2 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EIW85617.1 - 1.1e-05 24.7 0.1 2e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 EIW85617.1 - 0.0059 15.9 0.1 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase DUF2235 PF09994.4 EIW85619.1 - 4.7e-52 177.0 0.2 5.5e-52 176.8 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EIW85619.1 - 0.099 12.4 0.0 0.41 10.3 0.0 1.7 1 1 0 2 2 2 0 Alpha/beta hydrolase family AA_kinase PF00696.23 EIW85620.1 - 1.5e-38 132.7 2.0 2.4e-38 132.0 1.4 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EIW85620.1 - 8.2e-13 47.8 2.4 6e-07 29.0 1.5 2.6 2 0 0 2 2 2 2 PUA domain Nucleotid_trans PF03407.11 EIW85620.1 - 0.084 12.6 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Glyco_transf_28 PF03033.15 EIW85621.1 - 1.6e-23 83.0 0.0 1.3e-22 80.1 0.0 2.5 1 1 1 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EIW85621.1 - 0.00036 19.1 0.1 0.00056 18.5 0.1 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.6 EIW85621.1 - 0.00044 20.3 0.0 0.0029 17.7 0.0 2.3 2 0 0 2 2 2 1 ATG C terminal domain Glyco_tran_28_C PF04101.11 EIW85621.1 - 0.0014 18.3 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain DUF2701 PF10857.3 EIW85621.1 - 0.021 14.5 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2701) DUF2981 PF11200.3 EIW85621.1 - 0.26 10.3 0.0 0.4 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DIM PF08194.7 EIW85622.1 - 0.23 11.4 1.8 0.75 9.8 0.2 2.4 2 0 0 2 2 2 0 DIM protein LRR_6 PF13516.1 EIW85623.1 - 0.19 11.9 1.5 73 3.9 0.0 4.6 5 0 0 5 5 5 0 Leucine Rich repeat F-box-like PF12937.2 EIW85624.1 - 3.6e-08 32.9 2.0 1.1e-05 25.0 0.0 2.9 2 1 0 2 2 2 2 F-box-like F-box PF00646.28 EIW85624.1 - 0.092 12.4 0.7 66 3.3 0.0 3.8 4 0 0 4 4 4 0 F-box domain F-box-like PF12937.2 EIW85625.1 - 4.9e-05 22.9 0.1 0.00017 21.2 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW85625.1 - 0.064 12.9 0.1 0.23 11.1 0.1 1.9 1 0 0 1 1 1 0 F-box domain Asp PF00026.18 EIW85626.1 - 7.5e-37 127.2 0.4 2.6e-36 125.4 0.3 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW85626.1 - 1.3e-05 25.1 0.1 0.1 12.5 0.0 2.5 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIW85626.1 - 0.0053 16.3 0.4 0.17 11.4 0.1 2.9 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EIW85626.1 - 0.16 12.4 2.9 1.7 9.2 0.1 2.9 2 2 0 2 2 2 0 Aspartyl protease F-box-like PF12937.2 EIW85627.1 - 0.00029 20.4 0.1 0.0015 18.1 0.1 2.3 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIW85628.1 - 0.00088 18.9 0.0 0.0045 16.6 0.0 2.4 1 1 0 1 1 1 1 F-box-like F1F0-ATPsyn_F PF10791.4 EIW85629.1 - 1.9e-27 95.2 0.0 2.2e-27 95.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi NACHT PF05729.7 EIW85630.1 - 2.5e-06 27.2 0.0 3.2e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW85630.1 - 1.6e-05 24.9 0.0 1.8e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain APS_kinase PF01583.15 EIW85630.1 - 1.6e-05 24.5 0.0 2.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase RNA_helicase PF00910.17 EIW85630.1 - 4.6e-05 23.5 0.0 5.3e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 RNA helicase PRK PF00485.13 EIW85630.1 - 0.0004 20.0 0.0 0.00046 19.8 0.0 1.1 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.1 EIW85630.1 - 0.00053 20.1 0.0 0.0006 19.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIW85630.1 - 0.00053 20.2 0.0 0.00065 20.0 0.0 1.1 1 0 0 1 1 1 1 ABC transporter AAA_18 PF13238.1 EIW85630.1 - 0.00071 19.8 0.0 0.00092 19.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.10 EIW85630.1 - 0.00078 19.1 0.0 0.00088 19.0 0.0 1.1 1 0 0 1 1 1 1 NTPase AAA_29 PF13555.1 EIW85630.1 - 0.00081 18.8 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EIW85630.1 - 0.0019 17.3 0.0 0.0024 17.0 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin AAA_25 PF13481.1 EIW85630.1 - 0.0022 17.4 0.0 0.0023 17.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EIW85630.1 - 0.0027 16.9 0.0 0.0027 16.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EIW85630.1 - 0.0051 16.3 0.0 0.0064 15.9 0.0 1.1 1 0 0 1 1 1 1 FtsK/SpoIIIE family KaiC PF06745.8 EIW85630.1 - 0.0071 15.4 0.0 0.0082 15.2 0.0 1.1 1 0 0 1 1 1 1 KaiC AAA_33 PF13671.1 EIW85630.1 - 0.014 15.2 0.1 0.021 14.7 0.1 1.4 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EIW85630.1 - 0.016 14.9 0.0 0.019 14.6 0.0 1.0 1 0 0 1 1 1 0 Archaeal ATPase AAA_17 PF13207.1 EIW85630.1 - 0.019 15.8 0.0 0.024 15.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EIW85630.1 - 0.02 13.7 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein CbiA PF01656.18 EIW85630.1 - 0.021 14.2 0.0 0.028 13.8 0.0 1.1 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.1 EIW85630.1 - 0.022 14.5 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EIW85630.1 - 0.024 14.0 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 EIW85630.1 - 0.024 13.3 0.0 0.024 13.3 0.0 1.0 1 0 0 1 1 1 0 TIP49 C-terminus UPF0079 PF02367.12 EIW85630.1 - 0.028 14.0 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 ArgK PF03308.11 EIW85630.1 - 0.037 12.8 0.0 0.042 12.6 0.0 1.1 1 0 0 1 1 1 0 ArgK protein AAA_23 PF13476.1 EIW85630.1 - 0.038 14.3 0.0 0.045 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EIW85630.1 - 0.046 12.9 0.0 0.054 12.7 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MobB PF03205.9 EIW85630.1 - 0.047 13.4 0.0 0.054 13.1 0.0 1.1 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PhoH PF02562.11 EIW85630.1 - 0.056 12.6 0.0 0.061 12.5 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein AAA_5 PF07728.9 EIW85630.1 - 0.057 13.1 0.0 0.074 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_31 PF13614.1 EIW85630.1 - 0.058 13.3 0.0 0.07 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EIW85630.1 - 0.059 13.5 0.0 0.069 13.3 0.0 1.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EIW85630.1 - 0.076 12.4 0.0 0.08 12.4 0.0 1.1 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF2075 PF09848.4 EIW85630.1 - 0.078 11.9 0.0 0.084 11.8 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.12 EIW85630.1 - 0.078 11.8 0.0 0.099 11.4 0.0 1.1 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CPT PF07931.7 EIW85630.1 - 0.083 12.5 0.0 0.1 12.2 0.0 1.2 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_10 PF12846.2 EIW85630.1 - 0.083 12.3 0.0 0.092 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA-like domain Sigma54_activ_2 PF14532.1 EIW85630.1 - 0.12 12.3 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 EIW85630.1 - 0.12 11.1 0.0 0.12 11.1 0.0 1.1 1 0 0 1 1 1 0 NB-ARC domain DUF87 PF01935.12 EIW85630.1 - 0.14 11.9 0.0 0.18 11.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 CoaE PF01121.15 EIW85630.1 - 0.14 11.5 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Dephospho-CoA kinase NACHT PF05729.7 EIW85631.1 - 0.0035 17.0 0.0 0.13 11.9 0.0 2.3 2 0 0 2 2 2 2 NACHT domain Phos_pyr_kin PF08543.7 EIW85637.1 - 9.8e-84 280.3 0.1 1.7e-82 276.3 0.1 2.0 1 1 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EIW85637.1 - 1.1e-42 146.1 0.1 1.4e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 TENA/THI-4/PQQC family PfkB PF00294.19 EIW85637.1 - 0.00021 20.5 0.0 0.0013 17.9 0.0 1.9 1 1 0 1 1 1 1 pfkB family carbohydrate kinase HhH-GPD PF00730.20 EIW85638.1 - 1e-21 77.2 0.0 2.2e-21 76.1 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EIW85638.1 - 4.2e-08 32.4 0.0 1.7e-07 30.5 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EIW85638.1 - 0.0038 17.3 0.2 0.2 11.8 0.0 2.8 3 0 0 3 3 3 1 Helix-hairpin-helix domain p450 PF00067.17 EIW85639.1 - 7.3e-75 252.2 0.0 8.3e-75 252.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW85640.1 - 5.9e-71 239.3 0.0 7.5e-71 239.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Mak10 PF04112.8 EIW85641.1 - 5.7e-29 100.4 0.0 1.2e-28 99.4 0.0 1.6 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase tRNA-synt_1b PF00579.20 EIW85642.1 - 4.7e-76 255.7 0.0 5.5e-76 255.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Asp PF00026.18 EIW85643.1 - 3.5e-43 148.0 7.6 9.2e-43 146.6 5.2 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW85643.1 - 0.0078 16.1 0.5 0.026 14.4 0.1 2.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 EIW85643.1 - 0.14 11.9 0.6 0.71 9.7 0.0 2.3 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EIW85643.1 - 0.99 9.9 4.4 3.2 8.3 0.5 2.8 2 2 0 2 2 2 0 Aspartyl protease F-box-like PF12937.2 EIW85644.1 - 4.3e-05 23.1 0.1 0.00017 21.2 0.1 2.1 1 0 0 1 1 1 1 F-box-like Gallidermin PF02052.10 EIW85644.1 - 0.046 13.8 0.1 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 Gallidermin F-box-like PF12937.2 EIW85645.1 - 1e-05 25.1 0.4 3.8e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 F-box-like EFG_C PF00679.19 EIW85645.1 - 0.11 12.3 0.1 2.1 8.2 0.0 2.3 2 0 0 2 2 2 0 Elongation factor G C-terminus F-box-like PF12937.2 EIW85647.1 - 1.6e-07 30.8 0.2 4.6e-07 29.4 0.1 1.8 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EIW85647.1 - 0.001 18.6 0.7 0.016 14.8 0.3 2.8 2 1 0 2 2 2 1 F-box domain Methyltransf_3 PF01596.12 EIW85648.1 - 1.5e-47 161.3 0.2 1.8e-47 161.0 0.2 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EIW85648.1 - 7.1e-16 58.9 0.0 1.2e-15 58.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIW85648.1 - 4.8e-10 39.3 0.1 6e-10 39.0 0.1 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EIW85648.1 - 8.7e-10 38.3 0.0 1.4e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW85648.1 - 1.9e-09 38.0 0.0 5.1e-09 36.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW85648.1 - 3.1e-08 33.6 0.0 6.4e-08 32.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EIW85648.1 - 5.9e-05 22.6 0.0 9.8e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.7 EIW85648.1 - 0.00047 20.5 0.0 0.0016 18.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EIW85648.1 - 0.00063 19.1 0.0 0.0009 18.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 GCD14 PF08704.5 EIW85648.1 - 0.0036 16.8 0.0 0.005 16.3 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_16 PF10294.4 EIW85648.1 - 0.059 12.8 0.0 0.08 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase CmcI PF04989.7 EIW85648.1 - 0.06 12.6 0.1 0.088 12.1 0.1 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase Connexin43 PF03508.8 EIW85648.1 - 1 8.6 5.3 0.37 10.0 0.7 2.2 2 0 0 2 2 2 0 Gap junction alpha-1 protein (Cx43) NAD_binding_6 PF08030.7 EIW85649.1 - 3.2e-19 69.3 0.0 4.6e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EIW85649.1 - 2e-18 66.1 0.0 7.1e-18 64.4 0.0 1.9 1 1 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EIW85649.1 - 4.6e-09 36.4 7.6 4.6e-09 36.4 5.3 2.0 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EIW85649.1 - 0.14 12.7 0.0 0.44 11.1 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DUF4584 PF15223.1 EIW85649.1 - 0.2 10.9 0.3 0.32 10.2 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4584) SUV3_C PF12513.3 EIW85652.1 - 3.8e-12 45.4 0.0 9e-12 44.2 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EIW85652.1 - 1.7e-09 37.4 0.0 3.7e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF3432 PF11914.3 EIW85654.1 - 0.088 12.8 3.6 0.13 12.3 2.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3432) F-box-like PF12937.2 EIW85655.1 - 1.5e-07 30.9 0.3 3.4e-07 29.8 0.2 1.6 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EIW85655.1 - 0.0085 15.7 0.1 0.025 14.2 0.1 1.8 1 1 0 1 1 1 1 F-box domain Methyltransf_3 PF01596.12 EIW85658.1 - 6.4e-48 162.5 0.0 8.2e-48 162.1 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EIW85658.1 - 3.2e-17 63.2 0.0 7.4e-17 62.1 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW85658.1 - 3.4e-12 46.9 0.1 7.3e-12 45.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW85658.1 - 6e-10 39.1 0.0 1e-09 38.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW85658.1 - 2.5e-09 36.9 0.0 3.2e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIW85658.1 - 5.9e-09 35.7 0.0 7.6e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 EIW85658.1 - 0.00018 21.9 0.0 0.00079 19.8 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EIW85658.1 - 0.00054 19.1 0.0 0.00073 18.6 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.5 EIW85658.1 - 0.0006 19.3 0.0 0.00084 18.9 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.10 EIW85658.1 - 0.00088 18.7 0.0 0.0013 18.1 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Ubie_methyltran PF01209.13 EIW85658.1 - 0.009 15.1 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CmcI PF04989.7 EIW85658.1 - 0.045 13.0 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase GCD14 PF08704.5 EIW85658.1 - 0.049 13.1 0.0 0.068 12.6 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit MgtE PF01769.11 EIW85659.1 - 3.4e-23 82.4 20.2 4e-08 33.6 0.3 3.9 3 1 1 4 4 4 3 Divalent cation transporter Ada3 PF10198.4 EIW85660.1 - 2e-23 82.5 0.0 2e-23 82.5 0.0 1.8 2 0 0 2 2 2 1 Histone acetyltransferases subunit 3 SPX PF03105.14 EIW85660.1 - 0.0025 17.6 0.1 0.0065 16.2 0.0 1.7 2 0 0 2 2 2 1 SPX domain Sds3 PF08598.6 EIW85660.1 - 0.038 13.5 3.6 0.015 14.7 0.7 1.6 2 0 0 2 2 2 0 Sds3-like Serglycin PF04360.7 EIW85660.1 - 0.37 10.5 5.6 0.71 9.5 1.4 2.6 2 0 0 2 2 2 0 Serglycin NACHT PF05729.7 EIW85661.1 - 8.5e-11 41.7 0.2 9.6e-10 38.3 0.0 2.9 3 2 0 3 3 3 1 NACHT domain AAA_16 PF13191.1 EIW85661.1 - 3.7e-09 36.8 2.6 8.3e-08 32.4 0.1 3.4 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 EIW85661.1 - 5.6e-05 23.2 0.0 0.00017 21.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EIW85661.1 - 0.00041 20.4 0.0 0.00086 19.4 0.0 1.5 1 0 0 1 1 1 1 RNA helicase APS_kinase PF01583.15 EIW85661.1 - 0.00045 19.9 0.0 0.00092 18.9 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase PRK PF00485.13 EIW85661.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EIW85661.1 - 0.0015 18.8 0.0 0.0034 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW85661.1 - 0.0042 17.9 0.0 0.016 15.9 0.0 2.1 1 0 0 1 1 1 1 AAA domain ArgK PF03308.11 EIW85661.1 - 0.012 14.3 0.0 0.02 13.6 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_29 PF13555.1 EIW85661.1 - 0.017 14.6 0.1 0.044 13.3 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EIW85661.1 - 0.021 14.4 0.0 0.038 13.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 EIW85661.1 - 0.022 15.0 0.0 0.044 14.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter NTPase_1 PF03266.10 EIW85661.1 - 0.024 14.3 0.0 0.042 13.5 0.0 1.3 1 0 0 1 1 1 0 NTPase Zeta_toxin PF06414.7 EIW85661.1 - 0.035 13.1 0.0 0.074 12.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Cytidylate_kin2 PF13189.1 EIW85661.1 - 0.054 13.3 0.0 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase-like family CbiA PF01656.18 EIW85661.1 - 0.059 12.7 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF258 PF03193.11 EIW85661.1 - 0.076 12.1 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF2075 PF09848.4 EIW85661.1 - 0.089 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 EIW85661.1 - 0.091 12.1 0.0 0.35 10.2 0.0 2.0 2 1 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 EIW85661.1 - 0.11 12.3 0.1 0.31 10.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain T2SE PF00437.15 EIW85661.1 - 0.16 10.8 0.0 0.4 9.5 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein Methyltransf_3 PF01596.12 EIW85662.1 - 4.6e-50 169.5 0.0 5.4e-50 169.3 0.0 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EIW85662.1 - 4.5e-19 69.2 0.0 6.8e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW85662.1 - 2e-13 50.9 0.0 3.4e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW85662.1 - 1.6e-12 47.2 0.0 2.9e-12 46.4 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EIW85662.1 - 1.4e-09 37.7 0.0 1.8e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EIW85662.1 - 6.2e-08 32.6 0.0 1.4e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW85662.1 - 2.6e-06 27.8 0.0 7.2e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW85662.1 - 5.5e-06 26.6 0.0 7.9e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW85662.1 - 0.0001 21.7 0.0 0.00019 20.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Cons_hypoth95 PF03602.10 EIW85662.1 - 0.00024 20.5 0.0 0.00034 20.0 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical protein 95 CMAS PF02353.15 EIW85662.1 - 0.00025 20.2 0.0 0.0003 19.9 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_15 PF09445.5 EIW85662.1 - 0.00078 19.0 0.0 0.001 18.6 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase CmcI PF04989.7 EIW85662.1 - 0.0017 17.7 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Cephalosporin hydroxylase GCD14 PF08704.5 EIW85662.1 - 0.0022 17.5 0.0 0.003 17.1 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Ubie_methyltran PF01209.13 EIW85662.1 - 0.0046 16.1 0.0 0.0065 15.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EIW85662.1 - 0.012 15.3 0.0 0.03 14.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.12 EIW85662.1 - 0.038 13.0 0.0 0.049 12.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.13 EIW85662.1 - 0.1 12.1 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 DUF633 PF04816.7 EIW85662.1 - 0.11 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF633) p450 PF00067.17 EIW85663.1 - 1.7e-08 33.4 0.3 2.8e-07 29.4 0.1 2.4 1 1 1 2 2 2 1 Cytochrome P450 p450 PF00067.17 EIW85664.1 - 1.9e-71 240.9 0.0 2.4e-71 240.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 EIW85666.1 - 4.5e-71 239.3 0.0 6.7e-71 238.7 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EIW85666.1 - 6.9e-27 93.6 0.9 7.7e-26 90.2 0.6 2.3 1 1 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ACP_syn_III PF08545.5 EIW85666.1 - 3.1e-05 23.5 0.2 8.3e-05 22.1 0.1 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EIW85666.1 - 0.00012 21.1 0.3 0.00035 19.6 0.1 1.7 1 1 1 2 2 2 1 Thiolase, N-terminal domain Acyl_transf_1 PF00698.16 EIW85667.1 - 4.9e-30 104.9 1.1 1e-29 103.9 0.8 1.5 1 1 0 1 1 1 1 Acyl transferase domain AMP-binding PF00501.23 EIW85668.1 - 1.9e-96 323.0 0.0 3e-96 322.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Condensation PF00668.15 EIW85668.1 - 1.3e-27 96.5 0.0 1.8e-27 95.9 0.0 1.2 1 0 0 1 1 1 1 Condensation domain AMP-binding_C PF13193.1 EIW85668.1 - 1e-10 42.4 0.2 2.7e-10 41.0 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PP-binding PF00550.20 EIW85668.1 - 1.6e-07 31.4 0.0 6.4e-07 29.5 0.0 2.1 2 0 0 2 2 2 1 Phosphopantetheine attachment site NfeD PF01957.13 EIW85669.1 - 0.051 13.7 0.4 0.051 13.7 0.3 2.8 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding UPF0233 PF06781.7 EIW85669.1 - 0.79 9.3 5.8 19 4.9 2.7 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) F-box-like PF12937.2 EIW85670.1 - 2.4e-07 30.3 8.5 0.00052 19.6 0.3 3.2 3 0 0 3 3 3 2 F-box-like zf-C2H2 PF00096.21 EIW85672.1 - 0.00012 22.1 12.2 0.25 11.7 0.2 3.7 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW85672.1 - 0.39 11.1 9.1 2.1 8.8 0.2 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-UBP PF02148.14 EIW85672.1 - 0.73 9.9 5.0 1.4 9.0 2.3 2.3 2 1 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein adh_short PF00106.20 EIW85674.1 - 3.1e-24 85.7 1.9 8.1e-24 84.4 1.3 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW85674.1 - 6.6e-19 68.6 1.5 1e-18 68.0 1.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW85674.1 - 3.4e-13 49.6 0.6 5.8e-13 48.9 0.4 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EIW85674.1 - 0.00019 21.5 0.8 0.00046 20.2 0.6 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EIW85674.1 - 0.00024 20.1 0.3 0.00037 19.4 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EIW85674.1 - 0.00089 18.7 1.4 0.0032 16.9 1.0 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EIW85674.1 - 0.013 15.5 0.1 0.03 14.3 0.1 1.6 1 0 0 1 1 1 0 NADH(P)-binding F_bP_aldolase PF01116.15 EIW85674.1 - 0.029 13.4 0.1 0.048 12.7 0.1 1.3 1 0 0 1 1 1 0 Fructose-bisphosphate aldolase class-II Eno-Rase_NADH_b PF12242.3 EIW85674.1 - 0.032 13.9 1.2 0.079 12.7 0.8 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase zf-H2C2_2 PF13465.1 EIW85675.1 - 0.045 14.0 1.6 0.045 14.0 1.1 2.9 3 0 0 3 3 3 0 Zinc-finger double domain RhoGEF PF00621.15 EIW85679.1 - 1.3e-41 142.4 0.5 2.1e-41 141.8 0.3 1.3 1 0 0 1 1 1 1 RhoGEF domain SH3_1 PF00018.23 EIW85679.1 - 8.3e-20 69.9 0.8 9.2e-12 44.1 0.1 2.8 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EIW85679.1 - 1.2e-19 69.6 1.0 3.9e-11 42.3 0.1 2.5 2 0 0 2 2 2 2 Variant SH3 domain EF-hand_4 PF12763.2 EIW85679.1 - 1.1e-15 57.2 0.0 2.4e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand WH2 PF02205.15 EIW85679.1 - 1.6e-10 40.2 1.7 3.7e-10 39.0 0.4 2.2 2 0 0 2 2 2 1 WH2 motif SH3_2 PF07653.12 EIW85679.1 - 5.6e-10 38.5 0.0 0.00027 20.3 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain EF-hand_7 PF13499.1 EIW85679.1 - 0.00023 21.2 0.0 0.00081 19.4 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EIW85679.1 - 0.0036 16.4 0.1 0.49 9.8 0.0 2.5 2 0 0 2 2 2 1 EF hand PH PF00169.24 EIW85679.1 - 0.0053 16.9 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 PH domain EF-hand_6 PF13405.1 EIW85679.1 - 0.029 14.2 0.1 4.4 7.4 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain DUF3886 PF13025.1 EIW85680.1 - 0.14 12.1 4.0 0.19 11.7 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) IPK PF03770.11 EIW85681.1 - 1.6e-39 135.6 0.0 9e-24 84.2 0.0 2.2 2 0 0 2 2 2 2 Inositol polyphosphate kinase Thaumatin PF00314.12 EIW85682.1 - 1.5e-17 63.7 2.6 1.8e-17 63.5 1.8 1.1 1 0 0 1 1 1 1 Thaumatin family p450 PF00067.17 EIW85684.1 - 2e-21 76.0 0.0 2.2e-21 75.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW85685.1 - 1.1e-13 50.5 0.0 1.2e-13 50.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW85686.1 - 3.7e-45 154.3 0.0 1.3e-25 89.8 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 Cation_efflux PF01545.16 EIW85687.1 - 4e-31 108.1 4.0 4.9e-31 107.8 2.8 1.1 1 0 0 1 1 1 1 Cation efflux family GST_N_3 PF13417.1 EIW85691.1 - 9.4e-09 35.3 0.0 1.8e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW85691.1 - 7.6e-06 25.7 0.8 2.3e-05 24.1 0.4 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW85691.1 - 0.00011 22.6 0.2 0.00029 21.2 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EIW85691.1 - 0.00011 22.0 0.0 0.00021 21.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW85691.1 - 0.0015 18.4 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pkinase PF00069.20 EIW85692.1 - 2.9e-36 124.9 0.0 4.3e-36 124.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW85692.1 - 1.9e-23 82.8 0.0 1.9e-18 66.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIW85692.1 - 1.8e-07 30.4 0.0 3.4e-07 29.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIW85692.1 - 0.0015 17.6 0.0 0.0027 16.7 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW85692.1 - 0.0072 16.0 0.0 0.016 14.9 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.20 EIW85693.1 - 3.5e-39 134.5 0.0 5e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW85693.1 - 2.7e-17 62.6 0.0 4.7e-17 61.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW85693.1 - 1e-05 25.3 0.3 6.5e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW85693.1 - 0.0012 17.9 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIW85693.1 - 0.09 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW85695.1 - 3.1e-11 43.4 0.8 2.4e-10 40.5 0.5 1.9 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIW85695.1 - 8.8e-07 28.7 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EIW85695.1 - 0.00063 19.1 0.1 0.097 12.0 0.1 2.2 2 0 0 2 2 2 2 RIO1 family zf-MYND PF01753.13 EIW85696.1 - 3.9e-13 49.0 10.5 5.4e-13 48.5 7.3 1.2 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 EIW85696.1 - 0.076 12.6 6.7 0.076 12.6 4.6 1.9 2 0 0 2 2 2 0 HIT zinc finger Ecl1 PF12855.2 EIW85696.1 - 0.97 8.7 7.3 2.9 7.2 5.1 1.9 1 1 0 1 1 1 0 Life-span regulatory factor Meleagrin PF08189.6 EIW85696.1 - 1.3 8.5 7.8 0.23 10.9 2.2 2.1 2 0 0 2 2 2 0 Meleagrin/Cygnin family Tnp_zf-ribbon_2 PF13842.1 EIW85696.1 - 1.7 9.0 9.5 3.1 8.2 6.6 1.5 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon DUF581 PF04570.9 EIW85696.1 - 3.1 7.1 9.1 2.2e+02 1.2 6.3 3.0 1 1 0 1 1 1 0 Protein of unknown function (DUF581) MFS_1 PF07690.11 EIW85697.1 - 1.8e-25 89.4 27.1 1.8e-25 89.4 18.8 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW85697.1 - 1.1e-05 24.2 7.9 1.1e-05 24.2 5.5 3.0 3 1 0 3 3 3 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW85698.1 - 3.7e-40 137.7 30.1 3.7e-40 137.7 20.9 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW85698.1 - 2.9e-06 26.1 27.6 6.2e-05 21.7 18.5 2.6 1 1 0 1 1 1 1 Sugar (and other) transporter C2 PF00168.25 EIW85700.1 - 1.5e-12 47.1 0.0 2.7e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 C2 domain MFS_1 PF07690.11 EIW85701.1 - 3.6e-39 134.4 30.0 5.9e-39 133.7 20.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW85701.1 - 3.7e-10 38.9 10.2 3.7e-10 38.9 7.1 2.3 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EIW85701.1 - 0.053 11.5 0.1 0.093 10.7 0.1 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family APH PF01636.18 EIW85702.1 - 2e-10 40.7 0.1 4e-10 39.8 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIW85702.1 - 8.1e-06 25.5 0.0 1.2e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Pkinase PF00069.20 EIW85706.1 - 1.1e-06 28.0 0.0 2.1e-06 27.0 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW85706.1 - 0.031 13.3 0.0 0.073 12.1 0.0 1.7 2 1 0 2 2 2 0 Protein tyrosine kinase p450 PF00067.17 EIW85707.1 - 3.9e-67 226.7 0.0 4.4e-67 226.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1097 PF06496.6 EIW85707.1 - 0.018 14.8 0.1 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1097) Microtub_assoc PF07989.6 EIW85708.1 - 1.5e-21 75.9 10.4 1.5e-21 75.9 7.2 7.1 8 3 2 10 10 10 2 Microtubule associated AAA_13 PF13166.1 EIW85708.1 - 1.8 6.9 93.9 0.011 14.2 21.0 4.9 2 1 3 5 5 5 0 AAA domain Pkinase PF00069.20 EIW85710.1 - 1.2e-43 149.1 0.0 1.6e-43 148.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW85710.1 - 1.4e-21 76.7 0.0 2.2e-17 62.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EIW85710.1 - 3.5e-06 26.9 0.5 2.6e-05 24.0 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW85710.1 - 0.13 11.2 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like HET PF06985.6 EIW85711.1 - 3.8e-23 82.1 0.0 7e-23 81.3 0.0 1.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C2H2_4 PF13894.1 EIW85714.1 - 0.05 13.9 1.9 0.36 11.2 0.3 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger Pkinase PF00069.20 EIW85715.1 - 1.2e-40 139.3 0.0 1.9e-40 138.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW85715.1 - 4.6e-18 65.2 0.0 1.1e-17 63.9 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW85715.1 - 7.2e-06 25.1 0.0 1e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW85715.1 - 0.0017 18.1 0.0 0.0047 16.6 0.0 1.8 1 1 0 1 1 1 1 Phosphotransferase enzyme family ABC1 PF03109.11 EIW85715.1 - 0.011 15.7 0.0 0.022 14.7 0.0 1.5 1 0 0 1 1 1 0 ABC1 family PLA2_B PF01735.13 EIW85716.1 - 9.8e-99 330.7 0.0 1.4e-98 330.1 0.0 1.3 1 0 0 1 1 1 1 Lysophospholipase catalytic domain COX5A PF02284.11 EIW85717.1 - 7.5e-40 135.2 0.1 9.3e-40 134.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va HHH_8 PF14716.1 EIW85717.1 - 0.1 12.7 0.1 0.21 11.7 0.1 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix domain Methyltransf_25 PF13649.1 EIW85718.1 - 2.5e-05 24.5 0.0 7e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW85718.1 - 0.0031 17.2 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain zf-MYND PF01753.13 EIW85719.1 - 3.7e-08 33.1 17.4 6.8e-08 32.2 12.0 1.5 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 EIW85721.1 - 0.016 15.0 9.0 0.03 14.1 6.3 1.4 1 0 0 1 1 1 0 MYND finger zf-MYND PF01753.13 EIW85722.1 - 0.00075 19.3 7.4 0.0012 18.6 5.1 1.3 1 0 0 1 1 1 1 MYND finger zf-CXXC PF02008.15 EIW85722.1 - 1.4 8.7 9.2 0.63 9.8 2.8 2.2 1 1 1 2 2 2 0 CXXC zinc finger domain Pkinase PF00069.20 EIW85723.1 - 1.3e-49 168.7 0.0 1.8e-49 168.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW85723.1 - 3.9e-24 85.1 0.0 1e-23 83.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EIW85723.1 - 0.0054 15.5 0.2 0.0079 15.0 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.1 EIW85723.1 - 0.011 14.6 0.1 0.043 12.7 0.1 1.8 1 1 0 1 1 1 0 Kinase-like APH PF01636.18 EIW85723.1 - 0.021 14.5 0.1 0.32 10.6 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.17 EIW85723.1 - 0.023 14.0 1.9 2.1 7.6 0.1 2.3 1 1 1 2 2 2 0 RIO1 family Cyclase PF04199.8 EIW85724.1 - 1.6e-17 63.6 0.3 3e-17 62.8 0.2 1.5 1 1 0 1 1 1 1 Putative cyclase Shugoshin_C PF07557.6 EIW85725.1 - 1.9e-09 36.7 3.7 1.9e-09 36.7 2.5 3.6 3 0 0 3 3 3 1 Shugoshin C terminus Shugoshin_N PF07558.6 EIW85725.1 - 0.00042 19.9 1.9 0.00042 19.9 1.3 1.9 2 0 0 2 2 2 1 Shugoshin N-terminal coiled-coil region DivIC PF04977.10 EIW85725.1 - 0.14 11.6 1.0 0.44 10.0 0.7 1.8 1 0 0 1 1 1 0 Septum formation initiator UPF0081 PF03652.10 EIW85730.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0081) MFS_1 PF07690.11 EIW85731.1 - 5.5e-45 153.6 42.6 5.5e-45 153.6 29.5 2.5 2 2 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW85731.1 - 1.3e-10 40.4 7.3 1.3e-10 40.4 5.1 3.0 1 1 2 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EIW85731.1 - 2.7e-07 29.1 12.4 4.6e-07 28.4 8.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) GST_N PF02798.15 EIW85732.1 - 1.3e-10 41.3 0.0 2.7e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EIW85732.1 - 9e-10 38.6 0.0 2.5e-09 37.1 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW85732.1 - 1.1e-06 28.4 0.0 2.9e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW85732.1 - 7.9e-06 25.6 0.2 3.1e-05 23.7 0.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EIW85732.1 - 3.9e-05 23.5 0.0 5.4e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EIW85732.1 - 0.085 13.3 0.0 0.13 12.7 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain zf-MYND PF01753.13 EIW85734.1 - 1.6e-10 40.6 9.4 2.4e-10 40.0 6.5 1.3 1 0 0 1 1 1 1 MYND finger zf-MYND PF01753.13 EIW85735.1 - 7e-12 45.0 14.9 1.4e-11 44.0 10.3 1.5 1 0 0 1 1 1 1 MYND finger HTH_31 PF13560.1 EIW85735.1 - 0.04 14.1 0.2 0.35 11.1 0.0 2.4 2 1 0 2 2 2 0 Helix-turn-helix domain GIT_SHD PF08518.6 EIW85735.1 - 0.13 11.6 0.1 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Spa2 homology domain (SHD) of GIT HET PF06985.6 EIW85737.1 - 2.4e-24 86.0 0.3 5.1e-24 85.0 0.1 1.7 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) SOCS_box PF07525.11 EIW85737.1 - 0.016 15.0 1.3 4.5 7.2 0.0 2.8 3 0 0 3 3 3 0 SOCS box PAT1 PF09770.4 EIW85739.1 - 0.65 8.1 15.7 0.82 7.8 10.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-MYND PF01753.13 EIW85740.1 - 1.8e-11 43.6 17.1 3.3e-11 42.8 11.9 1.4 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 EIW85740.1 - 0.4 10.0 8.8 0.92 8.8 6.0 1.7 1 1 0 1 1 1 0 Life-span regulatory factor zf-Mss51 PF13824.1 EIW85740.1 - 1.3 8.9 6.6 2.5 8.0 4.6 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Pro_isomerase PF00160.16 EIW85742.1 - 1.1e-21 77.6 0.1 3e-21 76.2 0.0 1.6 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD F-box-like PF12937.2 EIW85744.1 - 0.011 15.3 2.0 0.025 14.3 0.0 2.7 3 0 0 3 3 3 0 F-box-like F-box-like PF12937.2 EIW85745.1 - 0.00091 18.8 0.1 0.0029 17.2 0.1 2.0 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIW85746.1 - 1.3e-05 24.8 0.1 3.2e-05 23.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like WD40 PF00400.27 EIW85747.1 - 1.6e-22 78.5 12.7 1.6e-08 34.0 0.4 4.4 4 0 0 4 4 4 4 WD domain, G-beta repeat Gmad1 PF10647.4 EIW85747.1 - 0.044 13.1 0.0 0.16 11.3 0.0 2.0 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.1 EIW85747.1 - 0.07 12.5 0.8 2.2 7.6 0.0 2.5 2 1 0 2 2 2 0 PQQ-like domain Cytochrom_D1 PF02239.11 EIW85747.1 - 0.1 10.8 0.6 0.23 9.7 0.2 1.7 1 1 0 1 1 1 0 Cytochrome D1 heme domain Transposase_21 PF02992.9 EIW85749.1 - 2.6e-12 46.3 0.0 5.3e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 APC_crr PF05923.7 EIW85751.1 - 0.36 10.5 2.9 0.64 9.7 0.8 2.3 2 0 0 2 2 2 0 APC cysteine-rich region DUF605 PF04652.11 EIW85752.1 - 6.3 6.0 18.7 9.1 5.5 13.0 1.2 1 0 0 1 1 1 0 Vta1 like F-box-like PF12937.2 EIW85753.1 - 9.4e-07 28.4 0.4 3.7e-06 26.5 0.3 2.1 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EIW85753.1 - 0.022 14.4 0.7 5.8 6.6 0.1 2.5 2 0 0 2 2 2 0 F-box domain PP2C PF00481.16 EIW85754.1 - 2.2e-31 109.1 0.0 4.1e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EIW85754.1 - 8.8e-05 22.2 0.1 0.006 16.3 0.0 2.6 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EIW85754.1 - 0.00025 20.4 0.0 0.00041 19.8 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Myb_DNA-bind_2 PF08914.6 EIW85755.1 - 0.001 18.8 0.3 0.0027 17.4 0.2 1.7 1 0 0 1 1 1 1 Rap1 Myb domain Rap1-DNA-bind PF09197.5 EIW85755.1 - 0.67 10.5 5.5 0.14 12.7 0.4 2.3 2 0 0 2 2 2 0 Rap1, DNA-binding F-box-like PF12937.2 EIW85757.1 - 0.0016 18.1 0.1 0.0078 15.9 0.0 2.2 1 1 0 1 1 1 1 F-box-like ADH_N PF08240.7 EIW85760.1 - 8.3e-13 48.0 0.0 1.3e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW85760.1 - 1.3e-11 44.1 0.0 2.1e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW85760.1 - 7e-05 23.7 0.0 0.00013 22.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase WD40 PF00400.27 EIW85763.1 - 5.6e-107 346.2 58.6 9.4e-12 44.3 0.6 14.2 14 0 0 14 14 14 13 WD domain, G-beta repeat eIF2A PF08662.6 EIW85763.1 - 2.7e-14 53.3 2.7 0.0019 17.9 0.0 6.7 3 2 4 7 7 7 4 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.11 EIW85763.1 - 2.3e-08 32.7 3.3 0.0091 14.3 1.2 4.5 3 2 1 4 4 4 2 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 EIW85763.1 - 2.7e-05 23.1 14.7 1.2 7.8 0.6 5.5 1 1 2 3 3 3 3 Nup133 N terminal like Nup160 PF11715.3 EIW85763.1 - 3.2e-05 22.2 15.1 0.097 10.7 1.3 6.5 3 2 3 6 6 6 2 Nucleoporin Nup120/160 PD40 PF07676.7 EIW85763.1 - 6.6e-05 22.4 1.9 23 4.7 0.0 7.5 9 0 0 9 9 9 0 WD40-like Beta Propeller Repeat Gmad1 PF10647.4 EIW85763.1 - 0.00019 20.9 1.1 0.055 12.8 0.0 4.1 4 2 1 5 5 5 2 Lipoprotein LpqB beta-propeller domain PQQ_2 PF13360.1 EIW85763.1 - 0.00031 20.2 3.7 0.065 12.6 0.3 4.3 3 1 0 3 3 3 1 PQQ-like domain IKI3 PF04762.7 EIW85763.1 - 0.018 12.9 0.5 0.19 9.5 0.1 2.8 3 1 0 4 4 4 0 IKI3 family DUF4596 PF15363.1 EIW85763.1 - 0.033 14.1 4.0 0.077 12.9 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF4596) Hira PF07569.6 EIW85763.1 - 0.033 13.3 0.3 16 4.6 0.0 4.4 4 1 2 6 6 6 0 TUP1-like enhancer of split F-box-like PF12937.2 EIW85765.1 - 0.018 14.7 0.0 0.059 13.0 0.0 1.9 1 0 0 1 1 1 0 F-box-like Myelin-PO_C PF10570.4 EIW85768.1 - 0.00069 19.6 0.8 0.026 14.5 0.0 2.9 3 0 0 3 3 3 1 Myelin-PO cytoplasmic C-term p65 binding region DUF3326 PF11805.3 EIW85769.1 - 0.16 10.6 1.2 0.19 10.4 0.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) Aldo_ket_red PF00248.16 EIW85770.1 - 4e-63 212.8 0.0 4.6e-63 212.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF659 PF04937.10 EIW85772.1 - 0.003 17.0 0.0 0.0062 16.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF 659) WD40 PF00400.27 EIW85773.1 - 9.1e-116 374.0 35.9 1.1e-12 47.3 0.0 12.1 12 0 0 12 12 12 12 WD domain, G-beta repeat Nup160 PF11715.3 EIW85773.1 - 5.8e-12 44.5 13.7 0.013 13.6 0.0 8.1 3 2 4 8 8 8 4 Nucleoporin Nup120/160 eIF2A PF08662.6 EIW85773.1 - 1e-11 44.9 0.1 0.00012 21.9 0.0 4.9 3 2 3 6 6 6 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EIW85773.1 - 9.3e-10 37.9 5.9 3.6 7.3 0.0 8.3 9 0 0 9 9 9 2 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 EIW85773.1 - 1.2e-06 28.1 6.6 0.0021 17.5 3.0 4.2 1 1 2 3 3 3 3 PQQ-like domain Gmad1 PF10647.4 EIW85773.1 - 4e-06 26.4 0.0 0.096 12.0 0.0 3.9 3 2 1 4 4 4 2 Lipoprotein LpqB beta-propeller domain Nbas_N PF15492.1 EIW85773.1 - 2e-05 23.8 0.4 12 4.8 0.0 5.9 4 3 0 6 6 6 0 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.4 EIW85773.1 - 0.00021 20.5 0.1 3.5 7.0 0.0 5.4 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature Nucleoporin_N PF08801.6 EIW85773.1 - 0.00027 19.8 2.5 1.4 7.5 0.0 5.4 2 2 2 5 5 5 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 EIW85773.1 - 0.00034 19.0 0.1 0.023 13.0 0.0 3.4 3 1 1 4 4 4 1 Cytochrome D1 heme domain PQQ_3 PF13570.1 EIW85773.1 - 0.0032 17.7 4.1 61 4.0 0.0 6.3 7 1 1 8 8 7 0 PQQ-like domain Coatomer_WDAD PF04053.9 EIW85773.1 - 0.0077 15.0 0.0 2.8 6.6 0.0 3.3 2 1 1 4 4 4 1 Coatomer WD associated region TruB_C PF09142.6 EIW85773.1 - 0.017 14.7 0.1 14 5.4 0.0 4.3 4 0 0 4 4 4 0 tRNA Pseudouridine synthase II, C terminal Me-amine-dh_H PF06433.6 EIW85773.1 - 0.043 12.4 0.0 42 2.6 0.0 4.0 2 1 2 4 4 4 0 Methylamine dehydrogenase heavy chain (MADH) DUF3312 PF11768.3 EIW85773.1 - 0.089 10.9 0.0 2.1 6.4 0.0 3.1 5 0 0 5 5 5 0 Protein of unknown function (DUF3312) SdiA-regulated PF06977.6 EIW85773.1 - 0.13 11.2 0.0 4.3 6.1 0.0 2.5 2 0 0 2 2 2 0 SdiA-regulated Hira PF07569.6 EIW85773.1 - 0.14 11.3 0.1 11 5.1 0.0 3.7 2 1 3 5 5 5 0 TUP1-like enhancer of split CNH PF00780.17 EIW85773.1 - 0.18 11.1 0.0 9.8 5.4 0.0 3.0 4 0 0 4 4 4 0 CNH domain Pkinase PF00069.20 EIW85775.1 - 1.2e-60 204.8 0.0 1.6e-60 204.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW85775.1 - 1.9e-36 125.4 0.0 2.8e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Sad1_UNC PF07738.8 EIW85775.1 - 5.8e-17 61.7 0.0 3e-08 33.5 0.0 2.7 3 0 0 3 3 3 2 Sad1 / UNC-like C-terminal Kinase-like PF14531.1 EIW85775.1 - 2.1e-11 43.3 0.0 1.4e-08 34.0 0.0 2.2 1 1 1 2 2 2 2 Kinase-like FHA PF00498.21 EIW85775.1 - 1.2e-05 25.2 0.0 2.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 FHA domain Kdo PF06293.9 EIW85775.1 - 0.014 14.5 0.1 0.028 13.4 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW85775.1 - 0.11 12.2 0.1 1.1 8.9 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.20 EIW85776.1 - 4e-64 216.2 0.0 7.3e-64 215.4 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW85776.1 - 2.3e-32 112.1 0.0 1e-31 109.9 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EIW85776.1 - 9.7e-11 41.6 0.1 1.8e-10 40.7 0.1 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EIW85776.1 - 9.1e-10 37.9 0.0 4.3e-08 32.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EIW85776.1 - 6e-07 29.4 0.0 2e-06 27.7 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EIW85776.1 - 5.4e-05 22.3 0.0 0.0001 21.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EIW85776.1 - 0.0057 16.0 0.0 0.0094 15.3 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Pox_ser-thr_kin PF05445.6 EIW85776.1 - 0.14 10.9 0.7 0.21 10.3 0.1 1.5 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Jnk-SapK_ap_N PF09744.4 EIW85777.1 - 2.5e-06 27.5 6.4 0.011 15.7 0.9 2.1 1 1 1 2 2 2 2 JNK_SAPK-associated protein-1 ATG16 PF08614.6 EIW85777.1 - 7.6e-06 25.8 13.8 0.00019 21.3 0.7 2.3 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.3 EIW85777.1 - 0.00024 20.8 12.6 0.072 12.8 0.0 4.1 2 1 2 4 4 2 2 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.6 EIW85777.1 - 0.00033 20.4 3.4 0.017 15.0 0.0 3.2 3 1 0 3 3 3 1 Flagella accessory protein C (FlaC) BLOC1_2 PF10046.4 EIW85777.1 - 0.00093 19.2 9.5 0.13 12.4 2.9 2.4 2 0 0 2 2 2 2 Biogenesis of lysosome-related organelles complex-1 subunit 2 GAS PF13851.1 EIW85777.1 - 0.0021 17.2 12.8 0.021 14.0 5.5 2.6 1 1 2 3 3 3 2 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 EIW85777.1 - 0.0025 17.0 13.4 0.07 12.3 1.2 2.1 1 1 1 2 2 2 2 Reovirus sigma C capsid protein AAA_27 PF13514.1 EIW85777.1 - 0.003 15.3 5.3 0.0041 14.8 3.7 1.2 1 0 0 1 1 1 1 AAA domain NPV_P10 PF05531.7 EIW85777.1 - 0.0037 17.4 13.2 0.12 12.6 0.0 3.9 2 1 2 4 4 3 1 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.2 EIW85777.1 - 0.0037 16.6 11.8 0.0037 16.6 8.2 1.9 1 1 1 2 2 2 1 Mechanosensitive ion channel porin domain DUF342 PF03961.8 EIW85777.1 - 0.0048 15.3 6.9 0.057 11.8 0.2 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF342) GOLGA2L5 PF15070.1 EIW85777.1 - 0.0054 15.2 9.1 0.0066 15.0 6.3 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 Tropomyosin PF00261.15 EIW85777.1 - 0.0064 15.6 9.8 0.013 14.5 6.8 1.6 1 1 0 1 1 1 1 Tropomyosin IncA PF04156.9 EIW85777.1 - 0.0073 15.9 13.1 0.18 11.3 6.5 2.1 1 1 1 2 2 2 2 IncA protein DUF4238 PF14022.1 EIW85777.1 - 0.012 14.9 1.5 0.016 14.4 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4238) DUF3584 PF12128.3 EIW85777.1 - 0.012 12.9 9.6 0.015 12.6 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HAUS5 PF14817.1 EIW85777.1 - 0.012 14.1 9.5 0.015 13.8 6.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 AAA_13 PF13166.1 EIW85777.1 - 0.014 13.8 10.4 0.019 13.4 7.2 1.1 1 0 0 1 1 1 0 AAA domain Tropomyosin_1 PF12718.2 EIW85777.1 - 0.025 14.4 14.4 0.08 12.7 2.2 2.9 2 1 1 3 3 3 0 Tropomyosin like APG6 PF04111.7 EIW85777.1 - 0.033 13.2 12.0 0.17 10.9 3.2 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Mnd1 PF03962.10 EIW85777.1 - 0.039 13.6 9.8 0.096 12.3 6.8 1.7 1 1 0 1 1 1 0 Mnd1 family Baculo_PEP_C PF04513.7 EIW85777.1 - 0.047 13.5 11.7 0.77 9.5 3.7 2.5 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus MbeD_MobD PF04899.7 EIW85777.1 - 0.053 13.4 5.5 3.1 7.7 0.2 3.3 1 1 3 4 4 4 0 MbeD/MobD like DUF1664 PF07889.7 EIW85777.1 - 0.09 12.5 8.4 2.6 7.8 2.3 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 EIW85777.1 - 0.099 11.2 13.6 0.28 9.8 5.1 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein TBPIP PF07106.8 EIW85777.1 - 0.099 12.1 13.0 0.2 11.1 0.7 3.0 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Phage_GP20 PF06810.6 EIW85777.1 - 0.11 11.9 8.4 0.078 12.4 1.5 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 ApoO PF09769.4 EIW85777.1 - 0.21 11.2 1.8 0.32 10.7 0.3 1.8 1 1 1 2 2 2 0 Apolipoprotein O COG5 PF10392.4 EIW85777.1 - 0.25 11.3 11.5 0.43 10.5 0.9 2.4 1 1 0 2 2 2 0 Golgi transport complex subunit 5 Fib_alpha PF08702.5 EIW85777.1 - 0.28 11.3 12.7 3.7 7.6 5.1 3.0 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DivIC PF04977.10 EIW85777.1 - 0.31 10.5 8.1 6.7 6.2 0.0 3.7 2 2 2 4 4 4 0 Septum formation initiator Snapin_Pallidin PF14712.1 EIW85777.1 - 0.32 11.3 10.7 0.89 9.8 0.1 3.5 1 1 1 3 3 3 0 Snapin/Pallidin TPR_MLP1_2 PF07926.7 EIW85777.1 - 0.34 10.6 13.2 0.63 9.7 6.7 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ADIP PF11559.3 EIW85777.1 - 0.35 10.7 14.7 1 9.2 0.1 3.1 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding SlyX PF04102.7 EIW85777.1 - 0.45 10.9 10.3 2 8.8 0.4 4.2 2 2 2 4 4 4 0 SlyX PEP-utilisers_N PF05524.8 EIW85777.1 - 0.47 10.2 3.0 1.8 8.3 1.7 2.1 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal DUF2968 PF11180.3 EIW85777.1 - 0.74 9.1 8.4 1.8 7.9 0.8 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) CHDCT2 PF08074.6 EIW85777.1 - 0.75 9.5 4.2 1.3 8.7 1.6 2.0 1 1 1 2 2 2 0 CHDCT2 (NUC038) domain Fmp27_WPPW PF10359.4 EIW85777.1 - 0.77 8.1 11.8 1.2 7.4 3.9 2.1 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Rootletin PF15035.1 EIW85777.1 - 0.84 9.5 10.9 2.6 7.9 6.8 2.1 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion bZIP_1 PF00170.16 EIW85777.1 - 1.2 9.1 4.9 37 4.3 1.2 3.6 2 2 2 4 4 4 0 bZIP transcription factor XhlA PF10779.4 EIW85777.1 - 2.3 8.1 8.8 0.34 10.8 0.2 3.1 2 1 1 3 3 3 0 Haemolysin XhlA Syntaxin-6_N PF09177.6 EIW85777.1 - 2.6 8.5 9.3 10 6.5 1.2 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Spectrin PF00435.16 EIW85777.1 - 2.7 8.3 10.6 9.2 6.6 0.7 3.0 1 1 3 4 4 4 0 Spectrin repeat DUF972 PF06156.8 EIW85777.1 - 2.9 8.2 10.3 46 4.4 2.5 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) H-kinase_dim PF02895.9 EIW85777.1 - 3.8 7.9 6.3 73 3.8 4.3 2.8 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain AATF-Che1 PF13339.1 EIW85777.1 - 4.4 7.4 11.6 3.7 7.6 1.9 2.8 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Uds1 PF15456.1 EIW85777.1 - 4.7 7.2 12.1 2 8.3 2.0 2.5 1 1 1 2 2 2 0 Up-regulated During Septation CENP-F_leu_zip PF10473.4 EIW85777.1 - 7.4 6.4 14.4 11 5.9 1.4 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pkinase PF00069.20 EIW85778.1 - 1.8e-33 115.7 1.2 1.3e-23 83.4 0.1 2.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW85778.1 - 4.7e-16 58.6 0.1 5.3e-10 38.8 0.0 2.8 1 1 1 2 2 2 2 Protein tyrosine kinase FHA PF00498.21 EIW85778.1 - 1.5e-06 28.2 0.0 2.8e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EIW85778.1 - 0.0043 16.0 0.0 0.15 10.9 0.0 2.2 1 1 0 1 1 1 1 Kinase-like FAM24 PF15193.1 EIW85778.1 - 0.086 13.0 0.1 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 FAM24 family Pkinase PF00069.20 EIW85779.1 - 2.8e-69 233.1 0.0 3.4e-69 232.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW85779.1 - 3.6e-38 131.1 0.0 4.7e-38 130.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EIW85779.1 - 3.1e-14 52.8 0.1 5.6e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EIW85779.1 - 5.2e-09 35.4 0.0 6.5e-09 35.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EIW85779.1 - 0.00019 20.8 0.0 0.00033 20.0 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EIW85779.1 - 0.0005 19.2 0.0 0.00089 18.3 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW85779.1 - 0.00067 19.4 0.0 0.0039 16.9 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family SSXRD PF09514.5 EIW85780.1 - 0.0048 16.1 15.9 23 4.3 0.0 6.0 6 0 0 6 6 6 6 SSXRD motif 2OG-FeII_Oxy_3 PF13640.1 EIW85781.1 - 8.8e-05 22.9 0.0 0.00016 22.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIW85781.1 - 0.004 17.4 0.0 0.0078 16.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2951 PF11166.3 EIW85782.1 - 0.02 14.7 0.6 0.069 13.0 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) DUF848 PF05852.6 EIW85782.1 - 0.037 13.8 0.7 0.037 13.8 0.5 1.9 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF3323 PF11796.3 EIW85782.1 - 0.042 13.1 2.5 2.1 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function N-terminus (DUF3323) DUF2570 PF10828.3 EIW85782.1 - 0.12 12.0 1.9 0.23 11.0 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DivIC PF04977.10 EIW85782.1 - 6.3 6.3 6.4 6.3 6.3 3.3 1.8 2 0 0 2 2 2 0 Septum formation initiator Transposase_21 PF02992.9 EIW85783.1 - 1.3e-13 50.5 0.0 1.5e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 RAG1 PF12940.2 EIW85783.1 - 0.044 12.1 0.0 0.048 12.0 0.0 1.0 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1) Bestrophin PF01062.16 EIW85785.1 - 8.9e-08 31.4 0.1 9.7e-08 31.2 0.1 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Aminotran_5 PF00266.14 EIW85786.1 - 0.0036 16.0 0.0 0.0036 16.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Herpes_capsid PF06112.6 EIW85789.1 - 0.8 9.7 7.1 1.1 9.2 4.9 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein CDC45 PF02724.9 EIW85790.1 - 0.2 9.6 0.0 0.24 9.3 0.0 1.0 1 0 0 1 1 1 0 CDC45-like protein Arteri_Gl PF00951.13 EIW85793.1 - 8.7 5.8 8.8 1.2 8.7 0.2 2.8 3 0 0 3 3 3 0 Arterivirus GL envelope glycoprotein Arb1 PF09692.5 EIW85795.1 - 0.00064 18.6 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 eIF2A PF08662.6 EIW85798.1 - 9.6e-71 237.5 0.0 7.5e-70 234.5 0.0 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 EIW85798.1 - 0.024 13.9 0.0 0.2 10.9 0.1 2.6 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 EIW85799.1 - 2.9e-24 84.0 4.6 3.1e-07 30.0 0.0 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW85799.1 - 0.017 14.6 0.4 0.14 11.6 0.2 1.8 1 1 1 2 2 2 0 PQQ-like domain PD40 PF07676.7 EIW85799.1 - 0.043 13.4 1.0 0.79 9.4 0.0 2.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.1 EIW85799.1 - 0.051 12.6 0.1 1.9 7.5 0.0 2.2 1 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal WD40 PF00400.27 EIW85800.1 - 2e-78 255.7 33.9 2.5e-12 46.1 0.4 9.1 9 0 0 9 9 9 8 WD domain, G-beta repeat eIF2A PF08662.6 EIW85800.1 - 1e-10 41.6 0.0 1.8e-05 24.5 0.0 3.7 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIW85800.1 - 3.1e-06 25.6 14.3 0.032 12.3 0.0 6.0 3 2 5 8 8 8 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIW85800.1 - 3.9e-06 25.8 0.5 0.39 9.4 0.0 4.0 2 1 2 4 4 4 3 Nup133 N terminal like PQQ_2 PF13360.1 EIW85800.1 - 0.00028 20.4 0.1 0.035 13.5 0.0 2.9 2 2 0 2 2 2 1 PQQ-like domain YXWGXW PF12779.2 EIW85800.1 - 0.0072 16.1 1.1 0.12 12.3 0.1 2.7 2 0 0 2 2 2 1 YXWGXW repeat (2 copies) Nbas_N PF15492.1 EIW85800.1 - 0.011 14.8 0.4 9.6 5.2 0.0 3.6 3 1 1 4 4 4 0 Neuroblastoma-amplified sequence, N terminal Gmad1 PF10647.4 EIW85800.1 - 0.051 12.9 0.3 1.8 7.8 0.0 2.7 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain Cytochrom_D1 PF02239.11 EIW85800.1 - 0.07 11.4 0.1 4.6 5.4 0.0 3.1 4 0 0 4 4 4 0 Cytochrome D1 heme domain PD40 PF07676.7 EIW85800.1 - 0.12 12.1 1.8 42 3.9 0.1 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 EIW85800.1 - 1.7 8.0 6.5 40 3.6 0.0 4.8 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Dimer_Tnp_hAT PF05699.9 EIW85801.1 - 1.6e-14 53.2 0.1 1.7e-14 53.1 0.1 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DDE_1 PF03184.14 EIW85803.1 - 0.0017 17.5 0.0 0.0021 17.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_1 PF03184.14 EIW85804.1 - 3e-06 26.5 0.0 3.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIW85804.1 - 0.0086 15.8 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease Transposase_21 PF02992.9 EIW85806.1 - 0.00013 21.1 0.0 0.00025 20.1 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 Nop14 PF04147.7 EIW85806.1 - 0.057 11.3 6.9 0.078 10.9 4.8 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4218 PF13960.1 EIW85806.1 - 0.13 11.6 0.1 0.27 10.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) DUF1840 PF08895.6 EIW85806.1 - 0.36 10.8 1.3 1.9 8.5 1.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) zf-RVT PF13966.1 EIW85807.1 - 0.00017 21.8 0.1 0.00024 21.3 0.1 1.2 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase RNase_H PF00075.19 EIW85808.1 - 0.00077 19.8 0.4 0.0013 19.0 0.1 1.5 2 0 0 2 2 2 1 RNase H zf-CCHC PF00098.18 EIW85811.1 - 0.013 15.4 1.7 0.013 15.4 1.2 3.4 6 0 0 6 6 6 0 Zinc knuckle WD40 PF00400.27 EIW85812.1 - 8.6e-59 193.4 10.1 1.5e-11 43.6 0.1 5.1 5 0 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.3 EIW85812.1 - 7.3e-07 27.7 0.6 0.0088 14.2 0.0 3.2 1 1 1 3 3 3 2 Nucleoporin Nup120/160 PD40 PF07676.7 EIW85812.1 - 2.4e-05 23.8 1.0 7.2 6.4 0.0 4.9 5 0 0 5 5 5 2 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EIW85812.1 - 0.0003 20.5 0.0 0.0015 18.2 0.0 1.9 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EIW85812.1 - 0.001 17.9 0.1 0.85 8.2 0.0 3.1 1 1 0 2 2 2 2 Nup133 N terminal like TruB_C PF09142.6 EIW85812.1 - 0.0015 18.1 0.0 3.1 7.5 0.0 2.8 2 0 0 2 2 2 2 tRNA Pseudouridine synthase II, C terminal PQQ_2 PF13360.1 EIW85812.1 - 0.0022 17.4 0.2 3.8 6.8 0.0 2.8 1 1 0 2 2 2 2 PQQ-like domain Nbas_N PF15492.1 EIW85812.1 - 0.0036 16.4 0.1 4.5 6.2 0.0 3.6 2 1 2 4 4 4 1 Neuroblastoma-amplified sequence, N terminal Me-amine-dh_H PF06433.6 EIW85812.1 - 0.05 12.2 0.0 1.9 7.0 0.0 2.2 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) WD40 PF00400.27 EIW85813.1 - 1.9e-118 382.5 47.4 1.1e-11 44.0 0.1 13.5 13 0 0 13 13 13 13 WD domain, G-beta repeat Nup160 PF11715.3 EIW85813.1 - 1.9e-10 39.5 14.5 0.056 11.5 0.0 7.6 3 3 4 9 9 9 4 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EIW85813.1 - 6.5e-09 35.6 11.8 5.7e-05 22.6 0.1 5.1 2 2 2 5 5 5 2 PQQ-like domain eIF2A PF08662.6 EIW85813.1 - 1.2e-08 34.9 0.0 0.025 14.3 0.0 4.5 2 2 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EIW85813.1 - 3.7e-06 26.2 3.5 0.87 8.6 0.0 7.2 3 2 6 9 9 9 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 EIW85813.1 - 8.4e-06 24.7 1.3 0.34 9.6 0.4 3.8 3 1 1 4 4 4 2 Nup133 N terminal like PD40 PF07676.7 EIW85813.1 - 0.00023 20.7 8.1 3.1 7.5 0.0 6.7 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat PQQ_3 PF13570.1 EIW85813.1 - 0.011 16.0 10.9 0.95 9.8 0.1 6.1 4 2 2 6 6 6 0 PQQ-like domain TruB_C PF09142.6 EIW85813.1 - 0.056 13.0 0.1 12 5.6 0.0 3.9 3 0 0 3 3 3 0 tRNA Pseudouridine synthase II, C terminal NYD-SP28_assoc PF14775.1 EIW85813.1 - 0.16 11.6 1.0 1.5e+02 2.1 0.0 4.8 6 0 0 6 6 6 0 Sperm tail C-terminal domain F-box-like PF12937.2 EIW85814.1 - 0.081 12.6 1.1 0.47 10.2 0.0 2.8 3 0 0 3 3 3 0 F-box-like 2OG-FeII_Oxy_3 PF13640.1 EIW85815.1 - 1.3e-06 28.8 0.3 6.8e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIW85815.1 - 0.003 17.8 0.0 0.0095 16.2 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Myb_DNA-bind_2 PF08914.6 EIW85816.1 - 0.00035 20.2 2.0 0.00084 19.0 1.4 1.6 1 0 0 1 1 1 1 Rap1 Myb domain Dioxygenase_C PF00775.16 EIW85817.1 - 1.1e-52 177.9 0.0 1.6e-52 177.4 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EIW85817.1 - 2.5e-18 65.8 0.0 1.5e-17 63.2 0.0 2.1 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EIW85817.1 - 0.00068 19.6 0.1 0.0038 17.2 0.1 2.2 2 1 0 2 2 2 1 Carboxypeptidase regulatory-like domain ACOX PF01756.14 EIW85817.1 - 0.085 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA oxidase CDC73 PF05179.9 EIW85820.1 - 2.3e-49 168.2 7.8 2.3e-49 168.2 5.4 1.9 2 1 0 2 2 2 1 RNA pol II accessory factor, Cdc73 family CbiC PF02570.10 EIW85820.1 - 0.14 11.5 0.1 1.4 8.2 0.0 2.2 2 0 0 2 2 2 0 Precorrin-8X methylmutase WD40 PF00400.27 EIW85821.1 - 1.7e-62 205.2 17.0 7.4e-12 44.6 0.8 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat PD40 PF07676.7 EIW85821.1 - 3.3e-07 29.8 3.6 1.6 8.4 0.0 6.5 6 1 0 6 6 6 2 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EIW85821.1 - 6e-07 29.3 0.0 0.024 14.3 0.0 3.1 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Proteasome_A_N PF10584.4 EIW85821.1 - 2.4e-05 23.5 2.8 9.9 5.5 0.0 5.6 6 0 0 6 6 6 1 Proteasome subunit A N-terminal signature Nup160 PF11715.3 EIW85821.1 - 2.4e-05 22.6 0.2 0.023 12.8 0.0 3.6 3 1 1 4 4 4 2 Nucleoporin Nup120/160 Nbas_N PF15492.1 EIW85821.1 - 3.5e-05 23.0 1.2 3 6.8 0.0 4.7 1 1 4 5 5 5 2 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 EIW85821.1 - 0.00017 20.4 0.5 0.34 9.5 0.1 3.8 1 1 2 3 3 3 2 Nup133 N terminal like PQQ_2 PF13360.1 EIW85821.1 - 0.00033 20.1 1.8 0.047 13.1 1.0 3.5 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.1 EIW85821.1 - 0.0032 17.7 6.2 4.5 7.6 0.1 5.7 4 2 1 5 5 5 1 PQQ-like domain MORN_2 PF07661.8 EIW85821.1 - 0.032 14.2 0.0 1.4 9.2 0.0 3.4 5 0 0 5 5 5 0 MORN repeat variant 2OG-FeII_Oxy_3 PF13640.1 EIW85822.1 - 9.1e-05 22.9 0.1 0.00019 21.9 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIW85822.1 - 0.0019 18.4 0.0 0.0035 17.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Tail_P2_I PF09684.5 EIW85822.1 - 0.048 13.2 0.0 0.7 9.4 0.0 2.2 2 1 0 2 2 2 0 Phage tail protein (Tail_P2_I) OPA3 PF07047.7 EIW85823.1 - 8.5e-35 119.4 0.1 1.4e-34 118.7 0.0 1.3 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) FlxA PF14282.1 EIW85823.1 - 0.0046 16.8 1.1 0.0072 16.2 0.8 1.2 1 0 0 1 1 1 1 FlxA-like protein EAP30 PF04157.11 EIW85823.1 - 0.013 14.7 0.2 0.12 11.5 0.1 2.0 2 0 0 2 2 2 0 EAP30/Vps36 family Atg14 PF10186.4 EIW85823.1 - 0.018 14.0 0.3 0.026 13.5 0.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF948 PF06103.6 EIW85823.1 - 0.053 13.3 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF972 PF06156.8 EIW85823.1 - 0.054 13.8 0.1 0.095 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF4279 PF14106.1 EIW85823.1 - 0.056 13.3 0.2 0.1 12.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) MbeD_MobD PF04899.7 EIW85823.1 - 0.2 11.5 1.4 0.37 10.7 1.0 1.5 1 0 0 1 1 1 0 MbeD/MobD like WD40 PF00400.27 EIW85824.1 - 3.3e-104 337.4 47.9 3.3e-11 42.6 0.4 11.1 11 0 0 11 11 11 11 WD domain, G-beta repeat Nup160 PF11715.3 EIW85824.1 - 3e-11 42.1 13.9 0.046 11.8 0.0 8.3 4 2 4 8 8 8 5 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EIW85824.1 - 2.5e-10 40.2 4.6 3e-05 23.6 0.1 3.9 2 1 1 4 4 4 2 PQQ-like domain Nucleoporin_N PF08801.6 EIW85824.1 - 9.1e-08 31.2 2.0 0.89 8.2 0.0 6.2 1 1 2 5 5 5 3 Nup133 N terminal like eIF2A PF08662.6 EIW85824.1 - 2e-07 30.9 0.0 0.017 14.8 0.0 4.1 1 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EIW85824.1 - 0.0007 18.7 1.6 7.4 5.5 0.0 5.2 3 2 2 6 6 6 1 Neuroblastoma-amplified sequence, N terminal DUF1513 PF07433.6 EIW85824.1 - 0.18 10.6 0.4 5.5 5.7 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1513) Proteasome_A_N PF10584.4 EIW85824.1 - 3.4 7.0 8.2 87 2.5 0.0 5.8 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 EIW85825.1 - 1.7e-45 151.3 16.9 6.7e-10 38.4 0.2 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EIW85825.1 - 0.00074 17.7 4.5 1 7.3 0.1 4.5 1 1 3 4 4 4 2 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EIW85825.1 - 0.013 15.0 2.1 4.7 6.6 0.3 3.1 1 1 2 3 3 3 0 PQQ-like domain PQQ_3 PF13570.1 EIW85825.1 - 0.015 15.5 2.8 7.8 6.9 0.0 4.8 3 2 1 4 4 4 0 PQQ-like domain Nbas_N PF15492.1 EIW85825.1 - 0.025 13.6 0.1 1.4 7.9 0.0 3.2 2 2 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 EIW85825.1 - 0.19 11.4 3.5 91 2.8 0.0 5.4 7 0 0 7 7 7 0 WD40-like Beta Propeller Repeat Thioredoxin PF00085.15 EIW85826.1 - 4.8e-26 90.4 0.0 5.3e-26 90.3 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EIW85826.1 - 1.9e-07 31.1 0.0 3.1e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EIW85826.1 - 6.9e-07 29.4 0.0 4.9e-06 26.7 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EIW85826.1 - 1.7e-06 27.6 0.0 1.9e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIW85826.1 - 2.8e-06 26.9 0.0 3.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_7 PF13899.1 EIW85826.1 - 4.9e-05 23.2 0.0 6.3e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_9 PF14595.1 EIW85826.1 - 0.067 12.7 0.0 0.078 12.5 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin 2OG-FeII_Oxy_3 PF13640.1 EIW85827.1 - 8.2e-08 32.6 0.1 1.5e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIW85827.1 - 6.4e-07 29.5 0.0 1.1e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EIW85828.1 - 4.9e-07 30.1 0.1 1.3e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EIW85828.1 - 0.00026 21.2 0.0 0.00054 20.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily WD40 PF00400.27 EIW85829.1 - 2.4e-22 77.9 7.4 2.4e-05 24.0 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat Cellulase PF00150.13 EIW85830.1 - 2.1e-10 40.3 0.1 5.1e-08 32.4 0.0 3.0 2 2 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 EIW85830.1 - 0.00032 20.1 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 GMC_oxred_N PF00732.14 EIW85831.1 - 1.7e-54 184.9 0.0 2.4e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIW85831.1 - 3e-39 134.6 0.2 5e-39 133.8 0.1 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EIW85831.1 - 7e-05 22.7 0.0 0.00055 19.8 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIW85831.1 - 0.00015 20.8 0.0 0.0011 17.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIW85831.1 - 0.00037 19.5 0.1 0.00054 18.9 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EIW85831.1 - 0.0028 17.5 0.0 0.14 12.0 0.0 2.7 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EIW85831.1 - 0.0096 14.7 0.2 0.022 13.6 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EIW85831.1 - 0.013 15.5 0.0 0.14 12.2 0.1 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EIW85831.1 - 0.085 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EIW85831.1 - 0.12 11.4 0.0 0.18 10.8 0.0 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EIW85831.1 - 0.16 11.7 0.2 0.51 10.0 0.1 1.9 1 0 0 1 1 1 0 FAD-NAD(P)-binding Aldolase_II PF00596.16 EIW85833.1 - 2.8e-36 124.8 0.0 3.2e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain WD40 PF00400.27 EIW85835.1 - 2.4e-81 264.9 18.1 1.4e-12 47.0 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EIW85835.1 - 2.3e-13 49.1 6.7 0.0058 14.8 0.0 5.6 1 1 3 5 5 5 4 Nucleoporin Nup120/160 eIF2A PF08662.6 EIW85835.1 - 1.5e-08 34.5 0.0 0.058 13.0 0.0 3.3 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EIW85835.1 - 4.4e-08 32.3 3.0 0.084 11.6 0.1 3.8 1 1 1 3 3 3 3 Nup133 N terminal like Gmad1 PF10647.4 EIW85835.1 - 2e-07 30.7 1.5 0.00072 19.0 0.4 2.9 2 2 0 2 2 2 2 Lipoprotein LpqB beta-propeller domain PD40 PF07676.7 EIW85835.1 - 6.2e-06 25.7 0.1 6 6.6 0.0 5.0 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 EIW85835.1 - 3.2e-05 23.5 3.9 0.002 17.6 0.5 2.9 1 1 0 2 2 2 1 PQQ-like domain MMS1_N PF10433.4 EIW85835.1 - 0.0033 15.6 0.0 0.59 8.1 0.0 2.3 1 1 1 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term Nbas_N PF15492.1 EIW85835.1 - 0.0061 15.7 0.9 6.1 5.8 0.0 4.0 2 2 1 4 4 4 1 Neuroblastoma-amplified sequence, N terminal IKI3 PF04762.7 EIW85835.1 - 0.016 13.0 0.0 1 7.0 0.0 2.3 3 0 0 3 3 3 0 IKI3 family TruB_C PF09142.6 EIW85835.1 - 0.14 11.8 2.0 81 2.9 0.0 4.4 5 0 0 5 5 5 0 tRNA Pseudouridine synthase II, C terminal Proteasome_A_N PF10584.4 EIW85835.1 - 5.7 6.3 7.0 12 5.3 0.0 4.1 5 0 0 5 5 5 0 Proteasome subunit A N-terminal signature WD40 PF00400.27 EIW85838.1 - 1.2e-112 364.2 42.9 2e-13 49.6 0.0 11.1 11 0 0 11 11 11 11 WD domain, G-beta repeat Nbas_N PF15492.1 EIW85838.1 - 1.5e-08 34.0 4.1 0.04 13.0 0.0 6.3 2 2 4 7 7 7 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 EIW85838.1 - 7.4e-07 27.6 15.9 0.18 9.9 0.0 7.3 2 2 4 7 7 7 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EIW85838.1 - 2.2e-06 27.3 7.8 8e-06 25.4 1.7 3.4 3 1 1 4 4 4 2 PQQ-like domain PD40 PF07676.7 EIW85838.1 - 6.5e-06 25.6 6.4 1.1 8.9 0.0 7.3 8 0 0 8 8 8 2 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 EIW85838.1 - 0.0009 18.5 12.0 1.7 8.0 0.0 7.6 8 0 0 8 8 8 1 Proteasome subunit A N-terminal signature DUF1513 PF07433.6 EIW85838.1 - 0.0014 17.5 1.2 3.9 6.2 0.0 4.8 4 1 3 7 7 7 1 Protein of unknown function (DUF1513) Crystall_2 PF09076.5 EIW85838.1 - 0.0072 16.0 0.1 0.052 13.3 0.1 2.2 2 0 0 2 2 2 1 Beta/Gamma crystallin Apc4_WD40 PF12894.2 EIW85838.1 - 0.018 14.5 0.0 5.7 6.5 0.0 3.5 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain TruB_C PF09142.6 EIW85838.1 - 0.019 14.6 0.1 62 3.3 0.0 5.0 6 0 0 6 6 6 0 tRNA Pseudouridine synthase II, C terminal IKI3 PF04762.7 EIW85838.1 - 0.073 10.8 0.0 15 3.2 0.0 3.1 3 1 0 3 3 3 0 IKI3 family ADH_N PF08240.7 EIW85839.1 - 1.5e-26 92.2 0.4 2.3e-26 91.6 0.2 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW85839.1 - 3.3e-24 84.8 0.1 4.9e-24 84.3 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW85839.1 - 0.0018 19.1 0.4 0.0032 18.3 0.2 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Cpn10 PF00166.16 EIW85839.1 - 0.15 12.0 0.5 0.33 10.9 0.4 1.5 1 0 0 1 1 1 0 Chaperonin 10 Kd subunit AMP-binding PF00501.23 EIW85840.1 - 2.2e-99 332.7 0.0 4.3e-99 331.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EIW85840.1 - 2.1e-67 227.2 0.0 6.2e-67 225.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.15 EIW85840.1 - 1.8e-43 148.5 0.0 2.9e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 Condensation domain Acyl_transf_1 PF00698.16 EIW85840.1 - 5.6e-40 137.6 0.0 1.6e-39 136.1 0.0 1.8 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EIW85840.1 - 9.8e-36 123.1 0.6 4.5e-35 120.9 0.0 2.4 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EIW85840.1 - 4e-31 108.1 0.4 4e-31 108.1 0.3 3.2 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EIW85840.1 - 1.5e-30 105.4 0.3 6e-30 103.5 0.2 2.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EIW85840.1 - 3.3e-21 75.7 0.0 6.9e-21 74.6 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thioesterase PF00975.15 EIW85840.1 - 1.7e-19 71.0 0.0 3.3e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 EIW85840.1 - 6.1e-17 61.6 0.8 2.7e-09 37.1 0.0 2.9 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EIW85840.1 - 1.5e-10 41.8 0.4 8.2e-10 39.4 0.2 2.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Thiolase_N PF00108.18 EIW85840.1 - 0.0009 18.2 0.1 0.0026 16.8 0.1 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_zinc_N PF00107.21 EIW85840.1 - 0.0015 18.0 3.5 0.0035 16.8 0.2 3.0 3 0 0 3 3 2 1 Zinc-binding dehydrogenase DUF1967 PF09269.6 EIW85840.1 - 0.099 12.3 0.0 0.37 10.4 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1967) Met_10 PF02475.11 EIW85840.1 - 0.23 10.9 0.0 0.5 9.9 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein DUF2974 PF11187.3 EIW85840.1 - 0.28 10.5 0.0 0.59 9.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) ATS3 PF06232.6 EIW85840.1 - 0.42 10.1 0.1 2.5 7.7 0.0 2.2 2 0 0 2 2 2 0 Embryo-specific protein 3, (ATS3) ABC2_membrane_4 PF12730.2 EIW85842.1 - 0.0024 17.0 0.1 0.0024 17.0 0.0 3.2 3 1 0 3 3 3 1 ABC-2 family transporter protein DUF2214 PF09980.4 EIW85842.1 - 0.098 12.3 3.9 0.71 9.6 0.3 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2214) Dmrt1 PF12374.3 EIW85845.1 - 0.066 13.5 0.9 1.4 9.2 0.1 2.3 1 1 1 2 2 2 0 Double-sex mab3 related transcription factor 1 ABC_tran PF00005.22 EIW85846.1 - 3.6e-54 182.7 0.1 2.7e-33 115.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIW85846.1 - 3.6e-46 157.8 22.8 1.1e-30 106.9 7.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EIW85846.1 - 4.9e-12 46.4 1.0 0.048 13.6 0.1 4.5 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 EIW85846.1 - 6.8e-10 38.5 8.2 4.5e-06 26.0 0.9 4.3 2 2 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EIW85846.1 - 4.6e-08 32.4 0.9 0.0026 17.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EIW85846.1 - 1.5e-07 31.9 3.7 0.019 15.3 0.1 3.3 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EIW85846.1 - 9.4e-07 28.4 0.1 0.037 13.4 0.0 2.7 3 0 0 3 3 2 2 AAA domain Zeta_toxin PF06414.7 EIW85846.1 - 9.6e-07 28.0 0.2 0.01 14.9 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_16 PF13191.1 EIW85846.1 - 1.1e-06 28.8 3.0 0.025 14.5 0.2 2.8 2 2 0 2 2 2 2 AAA ATPase domain Miro PF08477.8 EIW85846.1 - 1.8e-06 28.4 0.8 0.13 12.7 0.0 3.1 3 0 0 3 3 2 2 Miro-like protein DUF258 PF03193.11 EIW85846.1 - 2.2e-06 26.9 0.1 0.032 13.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 T2SE PF00437.15 EIW85846.1 - 4.2e-06 25.8 0.0 0.0078 15.1 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.18 EIW85846.1 - 1.8e-05 24.6 0.2 0.11 12.4 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_10 PF12846.2 EIW85846.1 - 3.6e-05 23.3 1.6 0.052 12.9 0.0 3.4 4 0 0 4 4 3 2 AAA-like domain MobB PF03205.9 EIW85846.1 - 3.9e-05 23.3 0.9 0.088 12.5 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EIW85846.1 - 5.2e-05 22.7 2.0 0.02 14.3 0.2 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EIW85846.1 - 6.6e-05 23.0 0.7 0.84 9.7 0.0 3.7 3 1 0 3 3 3 1 AAA domain NACHT PF05729.7 EIW85846.1 - 7.9e-05 22.3 0.4 0.24 11.0 0.0 2.7 3 0 0 3 3 2 2 NACHT domain AAA_18 PF13238.1 EIW85846.1 - 0.00013 22.2 0.3 0.092 13.0 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EIW85846.1 - 0.00028 20.7 1.2 0.93 9.3 0.7 3.3 2 1 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EIW85846.1 - 0.00055 19.7 0.1 0.91 9.1 0.0 2.9 2 0 0 2 2 2 1 Archaeal ATPase AAA_30 PF13604.1 EIW85846.1 - 0.0009 18.8 0.0 0.15 11.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EIW85846.1 - 0.0014 17.5 0.0 1.2 7.9 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain AAA_15 PF13175.1 EIW85846.1 - 0.0015 17.6 0.1 0.089 11.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EIW85846.1 - 0.0016 17.9 0.1 0.24 10.8 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 EIW85846.1 - 0.0016 17.1 0.3 1.4 7.4 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_17 PF13207.1 EIW85846.1 - 0.0018 19.0 4.9 0.046 14.5 0.0 3.5 2 2 0 2 2 2 1 AAA domain DUF87 PF01935.12 EIW85846.1 - 0.0019 18.0 6.4 0.034 13.9 0.1 3.0 3 0 0 3 3 3 1 Domain of unknown function DUF87 PIF1 PF05970.9 EIW85846.1 - 0.0051 15.8 0.3 0.53 9.1 0.0 3.1 3 0 0 3 3 3 1 PIF1-like helicase AAA_19 PF13245.1 EIW85846.1 - 0.0082 15.8 0.1 2.8 7.7 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain Pox_A32 PF04665.7 EIW85846.1 - 0.011 15.0 1.0 2.6 7.2 0.1 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein ABC_ATPase PF09818.4 EIW85846.1 - 0.014 13.9 0.6 0.48 8.9 0.0 2.7 4 0 0 4 4 2 0 Predicted ATPase of the ABC class AAA_5 PF07728.9 EIW85846.1 - 0.024 14.3 0.3 0.31 10.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.24 EIW85846.1 - 0.024 14.8 0.2 8.9 6.5 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EIW85846.1 - 0.024 14.3 3.5 0.66 9.6 0.0 3.4 4 0 0 4 4 4 0 NTPase ATP_bind_1 PF03029.12 EIW85846.1 - 0.028 13.9 0.2 4.3 6.8 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 EIW85846.1 - 0.046 13.5 6.7 0.56 10.0 0.2 3.1 3 0 0 3 3 3 0 Dynamin family GTP_EFTU PF00009.22 EIW85846.1 - 0.049 13.0 0.1 3.8 6.8 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain UPF0079 PF02367.12 EIW85846.1 - 0.058 13.0 0.7 4.8 6.8 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 KAP_NTPase PF07693.9 EIW85846.1 - 0.078 11.9 0.0 10 4.9 0.0 2.5 2 0 0 2 2 2 0 KAP family P-loop domain ATP-synt_ab PF00006.20 EIW85846.1 - 0.09 12.2 0.0 9.3 5.6 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.4 EIW85846.1 - 0.11 11.9 0.7 13 5.3 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EIW85846.1 - 0.15 11.9 0.7 10 6.0 0.0 3.4 4 0 0 4 4 3 0 AAA domain DEAD PF00270.24 EIW85846.1 - 0.31 10.5 1.9 3.6 7.0 0.0 3.0 2 2 0 2 2 2 0 DEAD/DEAH box helicase RseC_MucC PF04246.7 EIW85846.1 - 1.6 8.2 7.0 17 4.9 0.3 3.1 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC ADH_N PF08240.7 EIW85847.1 - 3.6e-26 91.0 0.5 5.6e-26 90.4 0.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW85847.1 - 1.1e-25 89.7 0.1 1.6e-25 89.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW85847.1 - 8.1e-05 23.5 0.6 0.00013 22.8 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MFS_1 PF07690.11 EIW85848.1 - 3e-32 111.7 36.8 3.2e-32 111.6 20.8 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.11 EIW85848.1 - 0.08 11.6 6.7 0.045 12.4 0.2 2.6 1 1 2 3 3 3 0 BT1 family DUF3561 PF12084.3 EIW85848.1 - 0.085 12.7 0.0 0.085 12.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3561) Vpu PF00558.14 EIW85848.1 - 0.16 11.5 1.2 0.32 10.5 0.2 2.0 2 0 0 2 2 2 0 Vpu protein DUF1049 PF06305.6 EIW85848.1 - 0.44 10.0 0.0 0.44 10.0 0.0 3.6 5 0 0 5 5 5 0 Protein of unknown function (DUF1049) DUF4231 PF14015.1 EIW85848.1 - 5.6 7.0 12.2 0.31 11.0 1.4 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) WD40 PF00400.27 EIW85849.1 - 2.8e-128 413.7 34.6 2.4e-12 46.2 0.0 12.8 13 0 0 13 13 13 12 WD domain, G-beta repeat eIF2A PF08662.6 EIW85849.1 - 1.3e-09 38.0 0.0 0.0089 15.7 0.0 3.9 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIW85849.1 - 3.6e-07 28.7 13.2 0.044 11.9 0.1 7.8 2 1 4 6 6 6 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EIW85849.1 - 1.8e-06 27.0 3.2 2.2 6.9 0.0 6.4 3 2 4 7 7 7 1 Nup133 N terminal like PD40 PF07676.7 EIW85849.1 - 2.7e-06 26.9 2.8 1.8 8.3 0.0 6.0 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 EIW85849.1 - 0.00039 19.6 1.8 20 4.6 0.0 5.7 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Peptidase_S9_N PF02897.10 EIW85849.1 - 0.0012 17.5 0.1 35 2.8 0.0 4.9 4 2 1 5 5 5 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Nbas_N PF15492.1 EIW85849.1 - 0.0028 16.8 0.2 4.6 6.2 0.0 4.4 1 1 3 5 5 5 1 Neuroblastoma-amplified sequence, N terminal TruB_C PF09142.6 EIW85849.1 - 0.008 15.7 0.2 12 5.6 0.0 4.4 5 0 0 5 5 5 0 tRNA Pseudouridine synthase II, C terminal Cytochrom_D1 PF02239.11 EIW85849.1 - 0.0082 14.4 0.1 4.8 5.3 0.0 3.6 2 1 1 3 3 3 1 Cytochrome D1 heme domain DUF4596 PF15363.1 EIW85849.1 - 0.01 15.7 1.3 1.2 9.1 0.0 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4596) DUF1258 PF06869.7 EIW85849.1 - 0.022 13.8 0.1 0.69 8.9 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1258) NYD-SP28_assoc PF14775.1 EIW85849.1 - 0.51 10.0 5.1 69 3.2 0.0 5.4 7 0 0 7 7 7 0 Sperm tail C-terminal domain WD40 PF00400.27 EIW85850.1 - 6.2e-11 41.7 1.9 0.00028 20.6 0.0 3.3 2 1 0 2 2 2 2 WD domain, G-beta repeat PD40 PF07676.7 EIW85850.1 - 0.054 13.1 0.2 3.2 7.5 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DTHCT PF08070.6 EIW85850.1 - 6.7 7.4 10.4 18 6.0 2.0 2.5 1 1 1 2 2 2 0 DTHCT (NUC029) region DUF3500 PF12006.3 EIW85851.1 - 3.3e-73 246.3 0.0 4.3e-73 245.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) MFS_1 PF07690.11 EIW85852.1 - 1.7e-29 102.6 43.7 3.1e-28 98.4 12.7 3.8 2 2 2 4 4 4 3 Major Facilitator Superfamily DUF4231 PF14015.1 EIW85852.1 - 0.14 12.1 4.9 0.3 11.0 1.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) DUF1049 PF06305.6 EIW85852.1 - 5.7 6.4 6.7 2.2 7.7 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) WD40 PF00400.27 EIW85853.1 - 4.3e-81 264.1 21.9 3.7e-13 48.8 0.0 9.3 9 0 0 9 9 9 8 WD domain, G-beta repeat Nup160 PF11715.3 EIW85853.1 - 1.6e-06 26.5 5.6 0.28 9.2 0.0 5.4 1 1 3 5 5 5 3 Nucleoporin Nup120/160 eIF2A PF08662.6 EIW85853.1 - 2.8e-05 23.9 0.0 0.021 14.5 0.0 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EIW85853.1 - 4.1e-05 22.5 4.3 0.93 8.1 0.0 4.8 1 1 3 4 4 4 3 Nup133 N terminal like PD40 PF07676.7 EIW85853.1 - 0.00043 19.8 5.6 9.1 6.0 0.0 5.9 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat PQQ_2 PF13360.1 EIW85853.1 - 0.0064 15.9 0.4 0.46 9.9 0.1 3.2 2 1 0 2 2 2 1 PQQ-like domain Cytochrom_D1 PF02239.11 EIW85853.1 - 0.015 13.6 0.0 1.7 6.8 0.0 2.4 1 1 1 2 2 2 0 Cytochrome D1 heme domain SdiA-regulated PF06977.6 EIW85853.1 - 0.11 11.4 0.0 3.6 6.4 0.0 2.6 3 0 0 3 3 3 0 SdiA-regulated Proteasome_A_N PF10584.4 EIW85853.1 - 2.4 7.5 11.2 6.9 6.0 0.0 5.5 7 0 0 7 7 7 0 Proteasome subunit A N-terminal signature Cullin PF00888.17 EIW85854.1 - 1.8e-09 36.7 0.1 2.2e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Cullin family Amidohydro_3 PF07969.6 EIW85854.1 - 0.00089 18.5 0.2 0.0011 18.2 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Cullin PF00888.17 EIW85855.1 - 0.00023 19.8 0.1 0.00025 19.7 0.1 1.1 1 0 0 1 1 1 1 Cullin family WD40 PF00400.27 EIW85856.1 - 1.1e-120 389.6 44.4 5.3e-13 48.3 0.2 13.8 14 0 0 14 14 14 13 WD domain, G-beta repeat Nup160 PF11715.3 EIW85856.1 - 2.4e-11 42.4 16.9 0.044 11.9 0.2 8.2 3 2 3 7 7 7 4 Nucleoporin Nup120/160 eIF2A PF08662.6 EIW85856.1 - 1.8e-09 37.6 0.0 0.014 15.1 0.0 4.0 2 2 2 5 5 5 3 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EIW85856.1 - 1.3e-06 28.0 8.5 0.00091 18.7 2.1 4.4 1 1 2 3 3 3 3 PQQ-like domain Nucleoporin_N PF08801.6 EIW85856.1 - 0.0031 16.3 5.0 2.1 6.9 0.0 5.2 3 2 1 4 4 4 1 Nup133 N terminal like Proteasome_A_N PF10584.4 EIW85856.1 - 0.0075 15.5 6.1 0.48 9.8 0.0 5.9 7 0 0 7 7 7 1 Proteasome subunit A N-terminal signature Cytochrom_D1 PF02239.11 EIW85856.1 - 0.008 14.5 0.5 1.3 7.2 0.0 3.3 3 1 0 4 4 4 1 Cytochrome D1 heme domain DPPIV_N PF00930.16 EIW85856.1 - 0.015 13.8 0.2 53 2.2 0.0 4.5 3 2 0 4 4 4 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region PD40 PF07676.7 EIW85856.1 - 0.027 14.1 23.3 5.5 6.7 0.0 8.7 10 0 0 10 10 10 0 WD40-like Beta Propeller Repeat GSDH PF07995.6 EIW85856.1 - 0.03 13.4 0.0 3 6.8 0.0 3.6 3 1 0 3 3 3 0 Glucose / Sorbosone dehydrogenase Asp PF00026.18 EIW85857.1 - 2.5e-08 33.5 4.6 0.0024 17.1 0.0 2.8 3 1 0 3 3 3 2 Eukaryotic aspartyl protease HCV_NS5a_1a PF08300.8 EIW85857.1 - 0.51 10.2 6.8 1.9 8.4 4.7 1.9 1 1 0 1 1 1 0 Hepatitis C virus non-structural 5a zinc finger domain Glyco_hydro_3 PF00933.16 EIW85859.1 - 1e-76 257.7 0.0 1.6e-76 257.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIW85859.1 - 2.5e-70 236.5 0.3 6.5e-69 231.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIW85859.1 - 3.7e-22 78.0 0.3 7.4e-22 77.0 0.2 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EIW85859.1 - 6e-12 45.4 0.0 1.1e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 PA14 domain ADH_N PF08240.7 EIW85860.1 - 1.5e-29 101.9 3.2 2.8e-29 101.0 2.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW85860.1 - 1.4e-26 92.5 1.2 3e-26 91.4 0.2 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW85860.1 - 4.4e-07 30.8 0.8 6.9e-07 30.2 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW85861.1 - 9.3e-26 89.7 1.0 1.5e-25 89.0 0.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW85861.1 - 1.1e-24 86.4 0.9 2e-24 85.5 0.6 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW85861.1 - 5.5e-05 24.0 1.4 9.5e-05 23.2 1.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_25 PF01183.15 EIW85862.1 - 3.1e-51 173.7 3.9 3.5e-51 173.5 2.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Pkinase PF00069.20 EIW85863.1 - 1.7e-39 135.5 0.0 3.1e-21 75.7 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW85863.1 - 8.1e-14 51.3 0.4 0.00015 20.8 0.1 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EIW85863.1 - 0.093 11.5 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase zf-C2H2 PF00096.21 EIW85866.1 - 3.5e-08 33.3 10.6 0.00018 21.6 1.1 2.7 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW85866.1 - 1.2e-06 28.4 9.7 0.0035 17.5 0.8 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIW85866.1 - 2.6e-06 27.4 3.8 2.6e-06 27.4 2.6 2.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EIW85866.1 - 0.0067 16.3 3.3 0.024 14.5 0.3 2.4 2 0 0 2 2 2 1 C2H2-type zinc finger zf-UBR PF02207.15 EIW85866.1 - 0.18 11.5 1.1 0.32 10.7 0.8 1.3 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DUF4072 PF13284.1 EIW85866.1 - 2.2 8.5 5.1 0.75 10.0 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4072) Brix PF04427.13 EIW85868.1 - 1.1e-30 106.7 0.1 1.4e-30 106.4 0.1 1.1 1 0 0 1 1 1 1 Brix domain Gon7 PF08738.5 EIW85868.1 - 0.17 11.9 2.4 0.34 10.9 1.6 1.5 1 0 0 1 1 1 0 Gon7 family TMEM51 PF15345.1 EIW85869.1 - 0.022 14.4 0.0 0.022 14.4 0.0 3.1 2 1 0 3 3 3 0 Transmembrane protein 51 Rifin_STEVOR PF02009.11 EIW85869.1 - 0.026 14.1 4.5 0.068 12.7 3.1 1.6 1 1 0 1 1 1 0 Rifin/stevor family CcmD PF04995.9 EIW85869.1 - 0.059 13.1 2.5 0.14 11.8 1.7 1.6 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) Adeno_E3_CR2 PF02439.10 EIW85869.1 - 0.091 12.3 2.9 0.17 11.4 2.0 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 SKG6 PF08693.5 EIW85869.1 - 0.11 11.7 2.4 0.46 9.8 1.7 2.1 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Glyco_hydro_3 PF00933.16 EIW85871.1 - 6.9e-57 192.6 0.0 1.1e-56 192.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EIW85871.1 - 7e-42 143.4 0.2 1.1e-41 142.8 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EIW85871.1 - 2.5e-07 30.5 0.0 5.7e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyco_hydro_28 PF00295.12 EIW85872.1 - 7.8e-33 113.7 10.9 1.3e-32 113.0 7.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Lipase_GDSL PF00657.17 EIW85873.1 - 2.5e-15 56.9 0.3 2.9e-15 56.7 0.2 1.0 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Glyoxal_oxid_N PF07250.6 EIW85874.1 - 2.3e-46 157.8 0.0 1e-45 155.7 0.0 2.0 2 0 0 2 2 2 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EIW85874.1 - 5.9e-19 67.9 0.0 1.3e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Viral_coat PF00729.13 EIW85875.1 - 0.014 14.6 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Viral coat protein (S domain) Peptidase_C14 PF00656.17 EIW85876.1 - 6.1e-68 229.1 0.0 8e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 Caspase domain p450 PF00067.17 EIW85877.1 - 5.1e-25 87.9 0.0 3.9e-16 58.6 0.0 2.2 1 1 1 2 2 2 2 Cytochrome P450 DUF3759 PF12585.3 EIW85878.1 - 4.7e-30 103.3 8.8 5.3e-30 103.1 6.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) Duffy_binding PF05424.6 EIW85878.1 - 0.067 13.0 0.4 0.075 12.8 0.3 1.0 1 0 0 1 1 1 0 Duffy binding domain Alpha-amylase PF00128.19 EIW85879.1 - 1.1e-99 333.8 1.6 1.7e-99 333.2 1.1 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 EIW85879.1 - 0.00025 20.0 0.0 0.00041 19.3 0.0 1.2 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme DUF3459 PF11941.3 EIW85879.1 - 0.038 14.0 0.0 0.1 12.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3459) F-box-like PF12937.2 EIW85884.1 - 3.9e-12 45.6 0.4 1.5e-11 43.8 0.0 2.3 2 0 0 2 2 2 1 F-box-like UbiA PF01040.13 EIW85886.1 - 1e-29 103.5 25.1 1.3e-29 103.2 17.4 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family ABC_tran PF00005.22 EIW85887.1 - 4.8e-25 88.4 0.0 6.8e-25 87.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIW85887.1 - 1.3e-07 31.8 0.0 0.0031 17.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EIW85887.1 - 1.4e-05 24.5 0.0 3.4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain UPF0079 PF02367.12 EIW85887.1 - 3.4e-05 23.4 0.0 7.1e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 EIW85887.1 - 6.2e-05 23.0 0.1 0.00012 22.1 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EIW85887.1 - 0.00011 21.4 0.0 0.00016 20.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 EIW85887.1 - 0.00015 21.0 0.0 0.021 14.0 0.0 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EIW85887.1 - 0.0002 21.2 0.1 0.0022 17.8 0.0 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 EIW85887.1 - 0.00047 19.8 0.1 0.0024 17.6 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA_15 PF13175.1 EIW85887.1 - 0.00067 18.8 0.0 0.012 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 EIW85887.1 - 0.00076 19.8 0.0 0.00092 19.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EIW85887.1 - 0.0012 18.4 0.1 0.0038 16.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EIW85887.1 - 0.0016 18.1 0.1 0.0034 17.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EIW85887.1 - 0.0032 17.6 0.0 0.0058 16.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EIW85887.1 - 0.0078 15.9 0.2 0.083 12.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) T2SE PF00437.15 EIW85887.1 - 0.014 14.2 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 EIW85887.1 - 0.016 14.6 0.0 0.044 13.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EIW85887.1 - 0.021 15.1 0.0 0.052 13.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 EIW85887.1 - 0.029 13.9 0.1 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.1 EIW85887.1 - 0.033 15.0 0.2 0.15 12.8 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.8 EIW85887.1 - 0.035 13.0 0.1 0.47 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_33 PF13671.1 EIW85887.1 - 0.045 13.6 0.4 0.12 12.2 0.3 2.0 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 EIW85887.1 - 0.073 12.0 0.0 0.14 11.1 0.0 1.3 1 1 0 1 1 1 0 KAP family P-loop domain AAA_10 PF12846.2 EIW85887.1 - 0.097 12.0 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain ArgK PF03308.11 EIW85887.1 - 0.14 10.9 0.0 0.23 10.1 0.0 1.3 1 0 0 1 1 1 0 ArgK protein PIF1 PF05970.9 EIW85887.1 - 0.14 11.0 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase RNA_helicase PF00910.17 EIW85887.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase VirE PF05272.6 EIW85887.1 - 0.15 11.5 0.0 0.38 10.1 0.0 1.6 2 0 0 2 2 2 0 Virulence-associated protein E ABC_ATPase PF09818.4 EIW85887.1 - 0.23 9.9 0.5 9.1 4.7 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Hydrophobin PF01185.13 EIW85888.1 - 1.6e-21 76.5 7.0 1.8e-21 76.3 4.9 1.0 1 0 0 1 1 1 1 Fungal hydrophobin Peptidase_M30 PF10460.4 EIW85889.1 - 0.061 12.1 0.9 0.069 12.0 0.6 1.0 1 0 0 1 1 1 0 Peptidase M30 K_channel_TID PF07941.6 EIW85889.1 - 0.88 9.8 0.1 0.88 9.8 0.0 2.1 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DUF605 PF04652.11 EIW85890.1 - 0.034 13.5 25.6 0.055 12.8 17.7 1.3 1 0 0 1 1 1 0 Vta1 like Zip PF02535.17 EIW85890.1 - 0.21 10.5 0.4 0.31 9.9 0.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Suf PF05843.9 EIW85890.1 - 0.98 9.0 11.7 1.8 8.2 8.1 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.11 EIW85890.1 - 1.1 9.1 5.3 1.9 8.3 3.7 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.2 EIW85890.1 - 2.3 5.7 6.5 3.1 5.3 4.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Rtf2 PF04641.7 EIW85890.1 - 4.1 6.5 14.3 6.9 5.7 9.9 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger DDHD PF02862.12 EIW85890.1 - 6 6.6 10.8 12 5.5 7.5 1.5 1 0 0 1 1 1 0 DDHD domain Hydrophobin PF01185.13 EIW85892.1 - 3.2e-18 65.9 3.8 4.5e-18 65.4 2.7 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 EIW85893.1 - 9.7e-24 83.6 9.1 1.4e-23 83.1 6.3 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Toxin_29 PF08116.6 EIW85893.1 - 8.5 6.2 8.6 13 5.6 1.9 2.3 2 0 0 2 2 2 0 PhTx neurotoxin family p450 PF00067.17 EIW85894.1 - 3.5e-70 236.8 0.0 3.9e-70 236.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sod_Ni PF09055.6 EIW85895.1 - 0.13 12.6 0.0 0.31 11.4 0.0 1.6 1 0 0 1 1 1 0 Nickel-containing superoxide dismutase Hydrophobin PF01185.13 EIW85896.1 - 3.9e-21 75.2 8.7 3.9e-21 75.2 6.0 1.6 2 0 0 2 2 2 1 Fungal hydrophobin Hydrophobin PF01185.13 EIW85897.1 - 8.4e-23 80.6 8.3 9.4e-23 80.4 5.7 1.0 1 0 0 1 1 1 1 Fungal hydrophobin Pkinase PF00069.20 EIW85898.1 - 1.6e-62 211.0 0.0 1.9e-62 210.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW85898.1 - 3.4e-29 101.7 0.0 4.1e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW85898.1 - 9e-07 28.1 0.0 1.7e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIW85898.1 - 0.0051 15.8 0.0 0.008 15.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW85898.1 - 0.024 14.3 0.0 0.049 13.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Hydrophobin PF01185.13 EIW85899.1 - 6.4e-22 77.7 9.1 9.3e-22 77.2 6.3 1.2 1 0 0 1 1 1 1 Fungal hydrophobin p450 PF00067.17 EIW85900.1 - 5.5e-65 219.6 0.0 7.2e-65 219.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Hydrophobin PF01185.13 EIW85902.1 - 2.8e-23 82.1 9.4 3.2e-23 81.9 6.5 1.0 1 0 0 1 1 1 1 Fungal hydrophobin p450 PF00067.17 EIW85903.1 - 6.1e-47 160.1 0.0 7.2e-47 159.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW85904.1 - 0.054 11.9 0.0 0.06 11.8 0.0 1.0 1 0 0 1 1 1 0 Cytochrome P450 p450 PF00067.17 EIW85905.1 - 4.3e-71 239.8 0.0 5e-71 239.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW85906.1 - 9.3e-65 218.9 0.0 1e-54 185.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Cir_N PF10197.4 EIW85907.1 - 0.004 17.1 0.1 0.004 17.1 0.1 3.1 3 0 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF2360 PF10152.4 EIW85907.1 - 0.68 10.2 4.2 1.7 8.9 2.9 1.7 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) p450 PF00067.17 EIW85908.1 - 1.2e-67 228.4 0.0 1.8e-51 175.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF3039 PF11238.3 EIW85908.1 - 0.17 11.3 0.1 11 5.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) BTB PF00651.26 EIW85909.1 - 0.00027 20.8 0.0 0.00073 19.5 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Methyltransf_23 PF13489.1 EIW85910.1 - 7.7e-10 38.7 0.0 4.3e-09 36.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW85910.1 - 4.5e-08 32.8 0.0 1.1e-06 28.3 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW85910.1 - 4.4e-07 30.2 0.0 3.1e-06 27.5 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW85910.1 - 2e-05 23.8 0.0 6.1e-05 22.2 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EIW85910.1 - 6.2e-05 23.5 0.0 0.00033 21.1 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 EIW85910.1 - 0.0001 22.3 0.0 0.00019 21.5 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.7 EIW85910.1 - 0.00028 21.3 0.0 0.0018 18.7 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW85910.1 - 0.00037 20.8 0.0 0.001 19.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIW85910.1 - 0.0007 18.6 0.0 0.0016 17.4 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.15 EIW85910.1 - 0.024 13.6 0.0 0.054 12.5 0.0 1.6 1 1 1 2 2 2 0 Mycolic acid cyclopropane synthetase MTS PF05175.9 EIW85910.1 - 0.04 13.3 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.13 EIW85910.1 - 0.044 12.9 0.0 0.091 11.9 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase Exotox-A_target PF09102.5 EIW85910.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Exotoxin A, targeting DUF4449 PF14613.1 EIW85912.1 - 1.6e-26 93.1 3.2 2.5e-26 92.5 2.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4449) DUF2780 PF11075.3 EIW85917.1 - 0.021 14.9 0.0 5.4 7.0 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function VcgC/VcgE (DUF2780) Peptidase_A4 PF01828.12 EIW85918.1 - 1.2e-76 256.4 11.0 1.4e-76 256.1 7.6 1.1 1 0 0 1 1 1 1 Peptidase A4 family Pkinase PF00069.20 EIW85919.1 - 3.7e-61 206.5 0.0 1.6e-34 119.2 0.0 3.4 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EIW85919.1 - 2.5e-30 105.4 0.0 3.6e-13 49.1 0.0 3.4 3 0 0 3 3 3 3 Protein tyrosine kinase HGTP_anticodon2 PF12745.2 EIW85919.1 - 1.7e-23 83.1 0.0 1.7e-23 83.1 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs RWD PF05773.17 EIW85919.1 - 3.5e-13 49.4 0.0 1.1e-12 47.8 0.0 1.9 1 0 0 1 1 1 1 RWD domain tRNA-synt_His PF13393.1 EIW85919.1 - 1.4e-10 40.7 0.0 1.4e-10 40.7 0.0 2.1 2 0 0 2 2 2 1 Histidyl-tRNA synthetase GDPD PF03009.12 EIW85921.1 - 3e-33 115.3 0.0 4.1e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EIW85921.1 - 0.00028 20.9 0.1 0.00093 19.3 0.1 2.0 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF4098 PF13345.1 EIW85922.1 - 0.0048 16.8 1.3 0.099 12.6 0.0 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4098) DUF4098 PF13345.1 EIW85923.1 - 5.5e-07 29.4 6.5 0.022 14.6 0.6 3.7 3 0 0 3 3 3 3 Domain of unknown function (DUF4098) Methyltransf_16 PF10294.4 EIW85924.1 - 9.1e-13 48.0 0.0 1.4e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EIW85924.1 - 0.0038 17.7 0.0 0.0078 16.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW85924.1 - 0.11 12.5 0.2 0.34 10.9 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain Peptidase_A4 PF01828.12 EIW85925.1 - 4.3e-66 221.9 12.9 1.3e-64 217.1 9.0 2.0 1 1 0 1 1 1 1 Peptidase A4 family SIMPL PF04402.9 EIW85925.1 - 0.0032 17.3 0.6 0.22 11.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF541) SR-25 PF10500.4 EIW85925.1 - 6.2 6.2 13.1 10 5.4 9.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein p450 PF00067.17 EIW85926.1 - 4.4e-73 246.3 0.0 5e-73 246.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PqqD PF05402.7 EIW85927.1 - 0.052 13.5 0.0 0.095 12.7 0.0 1.4 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) F-box-like PF12937.2 EIW85928.1 - 0.04 13.6 0.0 0.18 11.5 0.0 2.2 1 1 0 1 1 1 0 F-box-like p450 PF00067.17 EIW85932.1 - 2.4e-73 247.2 0.0 2.8e-73 247.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Porin_4 PF13609.1 EIW85935.1 - 0.18 11.2 2.0 0.23 10.9 1.4 1.1 1 0 0 1 1 1 0 Gram-negative porin PyrI_C PF02748.10 EIW85937.1 - 0.032 13.6 1.2 0.088 12.2 0.8 1.7 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DDE_1 PF03184.14 EIW85939.1 - 1.5e-06 27.5 0.0 1.8e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIW85939.1 - 0.0006 19.5 0.0 0.00069 19.3 0.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease SSP160 PF06933.6 EIW85940.1 - 0.075 11.0 7.2 0.081 10.8 5.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Herpes_capsid PF06112.6 EIW85940.1 - 7 6.6 9.2 10 6.1 6.4 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein NACHT PF05729.7 EIW85941.1 - 2.4e-08 33.8 0.1 0.001 18.7 0.0 2.9 2 1 1 3 3 3 2 NACHT domain AAA_16 PF13191.1 EIW85941.1 - 2e-05 24.6 0.0 3.1e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW85941.1 - 0.00054 20.0 0.0 0.0022 18.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIW85941.1 - 0.022 14.9 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Arch_ATPase PF01637.13 EIW85941.1 - 0.023 14.4 0.0 0.045 13.4 0.0 1.4 2 0 0 2 2 2 0 Archaeal ATPase APS_kinase PF01583.15 EIW85941.1 - 0.04 13.5 0.0 0.082 12.5 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase ICMT PF04140.9 EIW85943.1 - 8.2e-06 25.9 0.1 1.3e-05 25.2 0.1 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIW85943.1 - 9e-06 25.7 0.2 1.5e-05 25.0 0.2 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.7 EIW85943.1 - 0.052 12.8 0.4 0.091 12.0 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 EIW85943.1 - 0.13 10.7 1.1 0.87 8.0 0.7 2.0 1 1 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family Pro_CA PF00484.14 EIW85944.1 - 1.3e-17 64.1 0.0 1.6e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase ICMT PF04140.9 EIW85945.1 - 3.3e-06 27.2 0.2 5.4e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EIW85945.1 - 5.6e-06 26.4 0.1 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EIW85945.1 - 0.0015 17.1 0.5 0.0076 14.8 0.4 1.9 1 1 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EIW85945.1 - 0.0033 16.7 0.0 0.0057 15.9 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Asp PF00026.18 EIW85946.1 - 2.3e-80 270.2 13.5 2.7e-80 269.9 9.4 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW85946.1 - 1.9e-05 24.6 4.0 0.00026 20.9 2.7 2.5 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIW85946.1 - 0.074 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal Asp PF00026.18 EIW85947.1 - 5.7e-83 278.7 13.6 6.8e-83 278.5 9.4 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW85947.1 - 9.3e-05 22.4 6.3 0.00037 20.4 4.4 2.0 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIW85947.1 - 0.0001 22.7 3.4 0.27 11.7 0.1 2.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EIW85947.1 - 0.0018 17.8 0.0 0.0035 16.8 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Asp PF00026.18 EIW85948.1 - 3.9e-79 266.1 10.5 4.7e-79 265.9 7.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW85948.1 - 0.00021 21.2 5.5 0.00057 19.8 1.9 2.6 1 1 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIW85948.1 - 0.038 13.5 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal MFS_1 PF07690.11 EIW85949.1 - 4.4e-19 68.4 42.0 2.8e-13 49.3 11.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EIW85949.1 - 0.00017 20.1 13.9 0.00017 20.1 9.7 2.5 1 1 1 2 2 2 1 MFS/sugar transport protein Pro_CA PF00484.14 EIW85950.1 - 4.5e-24 85.1 0.0 5.5e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase Peptidase_M3 PF01432.15 EIW85951.1 - 7.7e-107 358.1 0.0 1e-106 357.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 DUF3654 PF12376.3 EIW85951.1 - 0.099 12.4 0.1 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3654) NST1 PF13945.1 EIW85951.1 - 3.1 7.8 6.0 0.35 10.9 0.2 2.0 2 0 0 2 2 2 0 Salt tolerance down-regulator Methyltransf_22 PF13383.1 EIW85952.1 - 6.6e-28 97.8 0.0 8.5e-28 97.5 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 EIW85952.1 - 2.6e-09 37.2 0.0 3.8e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain F-box-like PF12937.2 EIW85953.1 - 0.027 14.1 0.7 0.087 12.5 0.2 2.1 2 0 0 2 2 2 0 F-box-like F-box PF00646.28 EIW85953.1 - 0.46 10.2 3.1 7.8 6.2 0.6 2.8 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 EIW85954.1 - 1.7e-07 30.8 0.1 4.1e-07 29.6 0.1 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EIW85954.1 - 0.027 14.1 0.2 12 5.7 0.0 3.2 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 EIW85954.1 - 0.15 11.7 0.6 6 6.6 0.0 3.6 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) Pectate_lyase_3 PF12708.2 EIW85955.1 - 1.9e-77 260.4 20.7 1.3e-61 208.6 7.4 3.5 4 0 0 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EIW85955.1 - 7e-06 25.4 3.0 0.046 13.2 0.1 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase F-box PF00646.28 EIW85956.1 - 0.0071 15.9 0.8 0.026 14.1 0.5 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EIW85956.1 - 0.0092 15.6 3.2 0.024 14.3 2.2 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EIW85956.1 - 0.052 13.3 0.4 13 5.6 0.1 3.1 3 0 0 3 3 3 0 Leucine rich repeat Pectate_lyase_3 PF12708.2 EIW85957.1 - 2.1e-70 237.3 10.7 2.4e-58 197.9 4.0 2.9 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EIW85957.1 - 0.00028 20.2 0.2 0.064 12.7 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Phosducin PF02114.11 EIW85959.1 - 5.6e-17 61.3 0.0 5.2e-07 28.6 0.0 3.1 3 0 0 3 3 3 3 Phosducin MFS_1 PF07690.11 EIW85960.1 - 3.9e-16 58.7 57.1 8.1e-12 44.5 24.6 2.8 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF1700 PF08006.6 EIW85960.1 - 3.9 6.7 14.4 0.43 9.8 0.8 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1700) Corona_5a PF06336.6 EIW85963.1 - 0.049 13.5 0.1 0.1 12.4 0.1 1.5 1 0 0 1 1 1 0 Coronavirus 5a protein LRR_4 PF12799.2 EIW85964.1 - 0.00083 18.9 2.2 6 6.6 0.0 4.9 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EIW85964.1 - 0.01 15.5 1.5 0.031 14.0 0.0 2.7 3 0 0 3 3 3 0 F-box-like MFS_1 PF07690.11 EIW85967.1 - 6.4e-42 143.5 21.2 6.4e-42 143.5 14.7 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW85967.1 - 3e-17 62.3 3.2 3e-17 62.3 2.2 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter YbgT_YccB PF08173.6 EIW85967.1 - 0.038 13.7 2.0 0.55 10.0 0.4 2.9 2 0 0 2 2 2 0 Membrane bound YbgT-like protein Epimerase PF01370.16 EIW85968.1 - 1.4e-21 77.0 0.1 2.2e-21 76.4 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EIW85968.1 - 1.1e-14 53.7 0.1 1.7e-14 53.2 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIW85968.1 - 2.9e-13 50.2 1.5 8.1e-13 48.7 1.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EIW85968.1 - 1.8e-12 46.6 0.7 6.4e-12 44.9 0.5 1.8 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EIW85968.1 - 2.3e-06 27.0 0.2 3.2e-06 26.5 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EIW85968.1 - 0.0025 17.7 1.8 0.0098 15.8 0.2 2.5 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EIW85968.1 - 0.015 14.9 0.2 0.17 11.5 0.2 2.3 1 1 0 1 1 1 0 KR domain Imp-YgjV PF10688.4 EIW85969.1 - 0.027 13.9 8.1 0.014 14.8 4.4 1.4 1 1 0 1 1 1 0 Bacterial inner membrane protein HTH_Tnp_4 PF13613.1 EIW85969.1 - 0.087 12.3 1.7 0.42 10.1 0.6 2.4 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease DUF267 PF03268.9 EIW85969.1 - 0.16 10.8 9.7 0.026 13.3 1.9 2.0 1 1 1 2 2 2 0 Caenorhabditis protein of unknown function, DUF267 SPC12 PF06645.8 EIW85969.1 - 0.34 10.7 8.9 0.24 11.2 0.2 2.8 1 1 1 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) UPF0239 PF06783.6 EIW85969.1 - 0.4 10.6 0.1 0.4 10.6 0.0 2.8 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0239) Wzy_C PF04932.10 EIW85969.1 - 3.6 7.3 8.8 5.9 6.6 6.1 1.5 1 1 0 1 1 1 0 O-Antigen ligase ERCC4 PF02732.10 EIW85970.1 - 7.4e-28 97.1 0.0 1.6e-27 95.9 0.0 1.6 1 0 0 1 1 1 1 ERCC4 domain FTCD_C PF04961.7 EIW85970.1 - 0.0022 17.4 0.0 0.0057 16.0 0.0 1.6 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase SE PF08491.5 EIW85971.1 - 1.7e-93 312.4 0.0 2.3e-93 312.0 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EIW85971.1 - 3e-10 39.7 1.1 1.3e-09 37.6 0.8 2.0 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EIW85971.1 - 1.2e-09 37.5 0.2 3.8e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIW85971.1 - 0.002 17.1 0.0 0.062 12.2 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 EIW85971.1 - 0.0029 16.7 0.0 0.022 13.8 0.0 2.0 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EIW85971.1 - 0.0051 16.8 0.1 0.011 15.7 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EIW85971.1 - 0.0051 15.4 0.9 0.4 9.2 0.1 2.6 3 0 0 3 3 3 1 Tryptophan halogenase FAD_binding_2 PF00890.19 EIW85971.1 - 0.0097 14.7 3.3 0.37 9.5 0.7 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_9 PF13454.1 EIW85971.1 - 0.023 14.4 0.2 0.27 10.9 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF1156 PF06634.7 EIW85971.1 - 0.048 13.4 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1156) Mqo PF06039.10 EIW85971.1 - 0.11 10.6 0.0 0.16 10.1 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.9 EIW85971.1 - 0.12 12.2 2.1 0.69 9.7 1.5 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F-box-like PF12937.2 EIW85973.1 - 3e-07 30.0 0.0 8.7e-07 28.5 0.0 1.9 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EIW85973.1 - 0.00083 19.0 2.3 0.82 9.4 0.0 3.1 3 0 0 3 3 3 2 Leucine rich repeat Hydrophobin PF01185.13 EIW85975.1 - 5.2e-22 78.1 5.3 7.2e-22 77.6 3.6 1.2 1 0 0 1 1 1 1 Fungal hydrophobin FAD_binding_4 PF01565.18 EIW85976.1 - 6.3e-17 61.3 2.8 1.3e-16 60.3 1.9 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EIW85976.1 - 1.4e-07 31.3 0.1 2.7e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like F-box-like PF12937.2 EIW85978.1 - 0.0048 16.5 0.2 0.021 14.5 0.1 2.2 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EIW85978.1 - 0.043 13.4 3.8 27 4.5 0.0 5.0 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) p450 PF00067.17 EIW85979.1 - 3.7e-72 243.3 0.0 1.4e-70 238.0 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 COesterase PF00135.23 EIW85983.1 - 9.7e-08 31.1 0.0 1.5e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family DUF4218 PF13960.1 EIW85987.1 - 0.0004 19.8 0.0 0.00068 19.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) Asp PF00026.18 EIW85990.1 - 1.7e-61 208.2 3.8 2e-61 207.9 2.7 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EIW85990.1 - 0.00053 19.5 0.0 0.0012 18.4 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EIW85990.1 - 0.0047 16.8 5.6 0.056 13.4 0.6 3.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal DSPc PF00782.15 EIW85992.1 - 3.6e-06 26.5 0.0 4.6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EIW85992.1 - 2.2e-05 24.5 0.0 5.7e-05 23.2 0.0 1.6 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 EIW85992.1 - 0.00048 19.5 0.0 0.00061 19.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 EIW85992.1 - 0.0018 17.7 0.0 0.0022 17.4 0.0 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 EIW85992.1 - 0.014 15.6 0.3 0.44 10.7 0.3 2.1 1 1 1 2 2 2 0 Tyrosine phosphatase family F-box-like PF12937.2 EIW85994.1 - 0.00074 19.1 0.0 0.0021 17.7 0.0 1.8 1 0 0 1 1 1 1 F-box-like Asp PF00026.18 EIW85995.1 - 6.5e-65 219.4 6.1 7.6e-65 219.2 4.2 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EIW85995.1 - 3.1e-05 23.5 0.1 0.0002 20.9 0.0 2.1 1 1 1 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EIW85995.1 - 0.00023 21.1 5.6 0.00085 19.3 1.8 2.8 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIW85995.1 - 0.001 19.5 1.2 0.011 16.2 0.0 2.8 3 0 0 3 3 3 1 Aspartyl protease Asp PF00026.18 EIW85996.1 - 1e-44 153.0 1.4 1.3e-44 152.7 1.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW85996.1 - 5.3e-05 23.2 0.0 0.00017 21.5 0.0 1.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIW85996.1 - 0.099 13.1 0.1 0.58 10.6 0.0 2.3 1 1 0 1 1 1 0 Aspartyl protease LRR_6 PF13516.1 EIW85997.1 - 2 8.7 5.2 96 3.5 0.0 6.0 8 0 0 8 8 8 0 Leucine Rich repeat Asp PF00026.18 EIW85998.1 - 6.1e-63 212.9 4.7 1.7e-31 109.6 0.5 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW85998.1 - 1.3e-06 28.4 0.5 1.3e-05 25.2 0.3 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EIW85998.1 - 0.002 17.7 0.0 0.0042 16.6 0.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal GATase PF00117.23 EIW85999.1 - 0.036 13.5 0.0 0.082 12.3 0.0 1.6 1 1 0 1 1 1 0 Glutamine amidotransferase class-I DUF2560 PF10834.3 EIW85999.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2560) p450 PF00067.17 EIW86000.1 - 7.7e-12 44.4 0.0 9e-12 44.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3188 PF11384.3 EIW86000.1 - 0.022 14.3 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) p450 PF00067.17 EIW86001.1 - 5.6e-45 153.7 0.0 6.4e-45 153.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW86002.1 - 1.3e-63 215.1 0.0 1.7e-63 214.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 YqzM PF14141.1 EIW86002.1 - 0.11 12.3 0.1 0.43 10.4 0.0 2.0 2 0 0 2 2 2 0 YqzM-like protein p450 PF00067.17 EIW86003.1 - 4e-67 226.7 0.0 5.1e-67 226.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW86004.1 - 3.9e-73 246.5 0.0 4.8e-73 246.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW86005.1 - 4.5e-62 210.0 0.0 5.8e-62 209.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EIW86006.1 - 2.2e-32 112.1 0.0 2e-17 62.9 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.17 EIW86007.1 - 4.1e-75 253.0 0.0 5e-75 252.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 2-oxoacid_dh PF00198.18 EIW86008.1 - 1e-46 159.1 0.0 1.9e-46 158.2 0.0 1.4 1 1 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EIW86008.1 - 4.9e-18 64.5 0.9 1.4e-17 63.0 0.2 2.0 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EIW86008.1 - 1.2e-10 40.8 0.3 2.2e-10 39.9 0.2 1.5 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EIW86008.1 - 2.7e-05 23.7 0.7 0.00013 21.5 0.3 2.2 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.1 EIW86008.1 - 0.0075 16.6 0.1 0.026 14.8 0.0 2.0 2 0 0 2 2 2 1 HlyD family secretion protein HlyD_2 PF12700.2 EIW86008.1 - 0.13 11.4 0.0 0.19 10.8 0.0 1.1 1 0 0 1 1 1 0 HlyD family secretion protein zf-C2H2_4 PF13894.1 EIW86011.1 - 6.7e-06 26.0 14.4 0.017 15.3 0.6 4.3 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EIW86011.1 - 1.4e-05 25.0 10.9 0.16 12.2 0.2 3.9 4 0 0 4 4 4 3 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 EIW86011.1 - 0.0011 19.1 7.2 3.4 8.1 0.0 4.4 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 EIW86011.1 - 0.0034 17.6 18.1 0.012 15.9 0.9 4.4 5 0 0 5 5 5 2 Zinc finger, C2H2 type DUF3505 PF12013.3 EIW86011.1 - 0.29 11.3 9.9 9 6.5 0.1 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3505) zf-CCCH_2 PF14608.1 EIW86011.1 - 5.3 7.1 22.9 1.8 8.7 0.8 4.4 4 0 0 4 4 4 0 Zinc finger C-x8-C-x5-C-x3-H type zf-UBR PF02207.15 EIW86012.1 - 3.7e-16 58.6 14.8 3.7e-16 58.6 10.3 2.7 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EIW86012.1 - 5.8e-10 38.7 0.0 1.2e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS ELL PF10390.4 EIW86012.1 - 0.29 10.3 0.0 1.3 8.1 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase II elongation factor ELL GMC_oxred_C PF05199.8 EIW86014.1 - 3e-15 56.7 0.1 3e-15 56.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EIW86015.1 - 1.3e-56 191.9 0.0 1.6e-56 191.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EIW86015.1 - 4.6e-28 98.3 0.0 9.4e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIW86015.1 - 5.3e-06 25.5 0.2 7.8e-05 21.7 0.1 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EIW86015.1 - 4e-05 22.7 0.1 6.2e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EIW86015.1 - 0.00066 18.6 0.2 0.017 14.0 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EIW86015.1 - 0.001 19.0 0.0 0.0021 18.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF1589 PF07628.6 EIW86015.1 - 0.002 18.0 4.0 0.023 14.6 0.3 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF1589) Pyr_redox_2 PF07992.9 EIW86015.1 - 0.013 15.4 0.0 0.043 13.7 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW86015.1 - 0.11 10.9 0.0 0.16 10.3 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein GATase PF00117.23 EIW86017.1 - 0.0032 16.9 0.0 0.019 14.4 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase class-I DUF3253 PF11625.3 EIW86017.1 - 0.097 12.5 0.0 1.5 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3253) adh_short PF00106.20 EIW86018.1 - 5.6e-33 114.2 2.5 7.5e-33 113.7 1.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW86018.1 - 1.2e-24 87.4 2.0 2.9e-24 86.1 1.4 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW86018.1 - 6.1e-17 61.8 0.7 8.8e-17 61.3 0.5 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EIW86018.1 - 0.0013 18.3 1.2 0.0025 17.4 0.8 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GYD PF08734.6 EIW86018.1 - 0.044 13.5 0.2 0.088 12.5 0.2 1.5 1 0 0 1 1 1 0 GYD domain AdoHcyase_NAD PF00670.16 EIW86018.1 - 0.067 13.0 1.6 0.14 11.9 1.1 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Robl_LC7 PF03259.12 EIW86018.1 - 0.073 12.6 1.2 0.6 9.7 0.3 2.5 2 0 0 2 2 2 0 Roadblock/LC7 domain Methyltransf_11 PF08241.7 EIW86018.1 - 0.13 12.7 0.1 0.32 11.5 0.1 1.6 1 1 0 1 1 1 0 Methyltransferase domain Glucan_synthase PF02364.10 EIW86021.1 - 0.032 12.1 0.0 0.042 11.7 0.0 1.1 1 0 0 1 1 1 0 1,3-beta-glucan synthase component CD99L2 PF12301.3 EIW86021.1 - 0.058 13.0 0.0 0.083 12.5 0.0 1.2 1 0 0 1 1 1 0 CD99 antigen like protein 2 Cauli_VI PF01693.11 EIW86027.1 - 1.2e-07 31.6 0.0 1.9e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Caulimovirus viroplasmin Nebulin PF00880.13 EIW86028.1 - 0.0071 15.9 0.4 0.98 9.1 0.0 3.2 2 0 0 2 2 2 2 Nebulin repeat BRO1 PF03097.13 EIW86032.1 - 1.2e-98 330.4 0.5 1.1e-97 327.1 0.1 2.1 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EIW86032.1 - 3.2e-28 98.5 4.5 4.7e-28 98.0 3.1 1.2 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV Pkinase PF00069.20 EIW86035.1 - 3.3e-62 209.9 0.0 4.9e-62 209.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW86035.1 - 9.7e-34 116.6 0.0 4.4e-33 114.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EIW86035.1 - 5.9e-15 55.1 0.2 1.1e-14 54.3 0.2 1.4 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EIW86035.1 - 1.7e-06 27.2 0.0 2.2e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EIW86035.1 - 5.3e-06 25.6 0.0 8.8e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW86035.1 - 0.0017 18.1 0.0 0.049 13.3 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family RAP1 PF07218.6 EIW86035.1 - 0.026 12.6 0.3 0.035 12.2 0.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RIO1 PF01163.17 EIW86035.1 - 0.028 13.7 0.0 0.049 12.9 0.0 1.3 1 0 0 1 1 1 0 RIO1 family BTB PF00651.26 EIW86036.1 - 2.1e-05 24.4 0.0 3.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Snapin_Pallidin PF14712.1 EIW86040.1 - 0.025 14.8 1.7 0.35 11.1 0.4 2.6 1 1 0 2 2 2 0 Snapin/Pallidin EzrA PF06160.7 EIW86040.1 - 0.036 12.2 1.1 0.055 11.6 0.8 1.3 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Spc7 PF08317.6 EIW86040.1 - 0.086 11.4 4.7 0.15 10.6 1.9 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4200 PF13863.1 EIW86040.1 - 0.11 12.4 3.0 0.25 11.2 0.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Prefoldin_2 PF01920.15 EIW86040.1 - 0.15 11.7 5.1 7.3 6.4 0.8 3.1 1 1 1 2 2 2 0 Prefoldin subunit Spectrin PF00435.16 EIW86040.1 - 0.16 12.2 3.1 11 6.3 0.6 2.2 1 1 1 2 2 2 0 Spectrin repeat XhlA PF10779.4 EIW86040.1 - 0.27 11.1 3.2 13 5.8 0.0 2.6 2 1 1 3 3 3 0 Haemolysin XhlA TMF_DNA_bd PF12329.3 EIW86040.1 - 0.33 10.7 4.9 8.5 6.2 0.3 3.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Prefoldin PF02996.12 EIW86040.1 - 0.4 10.3 4.6 7.9 6.1 0.1 3.2 2 1 0 3 3 3 0 Prefoldin subunit IncA PF04156.9 EIW86040.1 - 0.45 10.0 7.5 6.1 6.3 5.2 2.2 1 1 0 1 1 1 0 IncA protein HSCB_C PF07743.8 EIW86040.1 - 0.68 10.4 5.4 3 8.3 1.3 2.7 1 1 1 2 2 2 0 HSCB C-terminal oligomerisation domain Ribosomal_L29 PF00831.18 EIW86040.1 - 3.3 7.4 5.0 10 5.8 0.1 2.7 2 1 0 2 2 2 0 Ribosomal L29 protein Sad1_UNC PF07738.8 EIW86041.1 - 3.9e-15 55.8 0.0 8.5e-08 32.0 0.0 2.5 1 1 1 2 2 2 2 Sad1 / UNC-like C-terminal WD40 PF00400.27 EIW86043.1 - 4.5e-11 42.1 1.6 2.8e-06 26.9 0.0 3.5 3 1 0 3 3 3 2 WD domain, G-beta repeat DUF4463 PF14703.1 EIW86045.1 - 0.032 14.7 9.4 0.077 13.5 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4463) CENP-H PF05837.7 EIW86046.1 - 0.0093 16.1 0.9 0.012 15.8 0.6 1.1 1 0 0 1 1 1 1 Centromere protein H (CENP-H) ADIP PF11559.3 EIW86046.1 - 0.0096 15.8 2.9 0.014 15.2 2.0 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding MscS_porin PF12795.2 EIW86046.1 - 0.022 14.0 1.5 0.026 13.8 1.0 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Spc7 PF08317.6 EIW86046.1 - 0.061 11.9 1.1 0.074 11.7 0.7 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein ATG16 PF08614.6 EIW86046.1 - 0.063 13.0 2.8 0.076 12.8 1.9 1.1 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Snapin_Pallidin PF14712.1 EIW86046.1 - 0.096 13.0 0.7 0.14 12.5 0.5 1.3 1 0 0 1 1 1 0 Snapin/Pallidin Fib_alpha PF08702.5 EIW86046.1 - 0.11 12.6 1.8 0.14 12.2 1.2 1.1 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Stn1_C PF12659.2 EIW86046.1 - 0.12 12.1 0.0 13 5.5 0.0 2.2 2 0 0 2 2 2 0 Telomere capping C-terminal wHTH GAS PF13851.1 EIW86046.1 - 0.13 11.4 1.4 0.15 11.2 1.0 1.1 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding IncA PF04156.9 EIW86046.1 - 0.15 11.6 4.9 0.23 11.0 3.4 1.3 1 1 0 1 1 1 0 IncA protein DUF904 PF06005.7 EIW86046.1 - 0.19 12.0 2.2 0.43 10.9 1.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Seryl_tRNA_N PF02403.17 EIW86046.1 - 0.29 11.1 2.4 0.98 9.4 1.7 1.8 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.3 EIW86046.1 - 0.91 9.3 4.8 2 8.2 2.8 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Abhydrolase_3 PF07859.8 EIW86047.1 - 8.5e-19 67.9 0.0 1.3e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EIW86047.1 - 4.4e-08 32.1 0.0 5.8e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Thioesterase PF00975.15 EIW86047.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain GATase PF00117.23 EIW86048.1 - 0.00049 19.5 0.1 0.0029 17.0 0.1 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Trp_halogenase PF04820.9 EIW86049.1 - 0.015 13.9 0.3 1 7.9 0.0 2.4 3 0 0 3 3 3 0 Tryptophan halogenase Phage_integrase PF00589.17 EIW86050.1 - 2e-06 27.6 0.0 5.8e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 Phage integrase family T4_neck-protein PF11649.3 EIW86050.1 - 0.17 11.1 0.0 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Virus neck protein TRAPP PF04051.11 EIW86052.1 - 1.1e-31 109.3 0.0 1.9e-31 108.6 0.0 1.5 1 1 0 1 1 1 1 Transport protein particle (TRAPP) component tRNA-synt_1c PF00749.16 EIW86053.1 - 5.9e-83 278.1 0.0 1e-82 277.3 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Aminotran_1_2 PF00155.16 EIW86054.1 - 8.1e-36 123.7 0.0 9.5e-36 123.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EIW86054.1 - 0.0046 16.1 0.0 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase DUF4131 PF13567.1 EIW86055.1 - 0.041 13.2 0.7 0.041 13.2 0.5 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) G-alpha PF00503.15 EIW86057.1 - 2.9e-48 164.5 0.2 3.4e-48 164.2 0.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIW86057.1 - 5.8e-09 35.4 0.1 1.1e-08 34.5 0.1 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW86057.1 - 0.05 12.7 0.0 0.056 12.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region A_deaminase PF00962.17 EIW86058.1 - 3.9e-22 78.5 0.0 7.5e-22 77.6 0.0 1.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase NACHT PF05729.7 EIW86060.1 - 1.3e-07 31.3 0.0 2e-07 30.7 0.0 1.3 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW86060.1 - 1.3e-05 25.3 0.0 1.6e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 EIW86060.1 - 0.00046 20.3 0.0 0.001 19.2 0.0 1.6 1 0 0 1 1 1 1 RNA helicase APS_kinase PF01583.15 EIW86060.1 - 0.00062 19.4 0.1 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.1 EIW86060.1 - 0.0013 18.9 0.1 0.002 18.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIW86060.1 - 0.0097 16.2 0.0 0.014 15.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EIW86060.1 - 0.011 14.7 0.0 0.053 12.4 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) PRK PF00485.13 EIW86060.1 - 0.011 15.2 0.1 0.013 15.0 0.1 1.4 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA PF00004.24 EIW86060.1 - 0.015 15.4 0.0 0.022 14.9 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EIW86060.1 - 0.03 15.1 0.0 0.034 14.9 0.0 1.3 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EIW86060.1 - 0.031 13.1 0.0 0.043 12.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 KAP_NTPase PF07693.9 EIW86060.1 - 0.031 13.2 0.1 1.4 7.8 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain ABC_tran PF00005.22 EIW86060.1 - 0.035 14.3 0.0 0.041 14.1 0.0 1.3 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 EIW86060.1 - 0.038 13.0 0.1 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin UPF0079 PF02367.12 EIW86060.1 - 0.045 13.3 0.0 0.074 12.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activ_2 PF14532.1 EIW86060.1 - 0.075 13.0 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 EIW86060.1 - 0.088 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family CobU PF02283.11 EIW86060.1 - 0.12 11.7 0.1 0.22 10.8 0.1 1.4 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase DUF815 PF05673.8 EIW86060.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) CoaE PF01121.15 EIW86060.1 - 0.15 11.4 0.1 0.33 10.3 0.1 1.6 1 1 0 1 1 1 0 Dephospho-CoA kinase OPT PF03169.10 EIW86062.1 - 8.2e-184 612.5 54.8 9.4e-184 612.3 38.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein HupE_UreJ_2 PF13795.1 EIW86062.1 - 0.18 11.2 3.7 0.48 9.8 0.0 3.1 3 0 0 3 3 3 0 HupE / UreJ protein PS_Dcarbxylase PF02666.10 EIW86063.1 - 8.8e-76 253.7 0.0 1.3e-73 246.6 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase AIG1 PF04548.11 EIW86065.1 - 6.9e-07 28.5 0.1 1.1e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 EIW86065.1 - 5.4e-06 26.3 0.0 8.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIW86065.1 - 1.3e-05 25.6 0.0 2e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EIW86065.1 - 0.00015 21.5 0.3 0.00074 19.3 0.1 2.0 1 1 0 2 2 2 1 Dynamin family Ras PF00071.17 EIW86065.1 - 0.0018 17.6 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 Ras family ABC_tran PF00005.22 EIW86065.1 - 0.0023 18.2 0.0 0.0036 17.6 0.0 1.7 1 1 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EIW86065.1 - 0.0066 15.6 0.1 0.013 14.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 EIW86065.1 - 0.023 14.1 0.3 0.075 12.4 0.2 1.8 1 1 1 2 2 2 0 AAA-like domain AAA_16 PF13191.1 EIW86065.1 - 0.044 13.7 0.0 0.068 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RHH_1 PF01402.16 EIW86065.1 - 0.054 13.4 0.9 0.11 12.4 0.6 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family FeoB_N PF02421.13 EIW86065.1 - 0.056 12.7 0.0 0.083 12.1 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B IIGP PF05049.8 EIW86065.1 - 0.056 12.2 0.1 0.069 11.9 0.1 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_29 PF13555.1 EIW86065.1 - 0.058 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2802 PF10975.3 EIW86065.1 - 0.081 12.6 0.5 0.15 11.8 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) FtsK_SpoIIIE PF01580.13 EIW86065.1 - 0.094 12.1 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EIW86065.1 - 0.1 11.7 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.1 EIW86065.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EIW86065.1 - 0.12 12.6 0.1 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AIG1 PF04548.11 EIW86066.1 - 5.7e-08 32.1 0.0 8e-08 31.6 0.0 1.2 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 EIW86066.1 - 1.8e-06 27.9 0.0 3.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EIW86066.1 - 0.00026 21.3 0.0 0.004 17.4 0.0 2.4 3 0 0 3 3 3 1 ABC transporter Dynamin_N PF00350.18 EIW86066.1 - 0.0014 18.4 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 EIW86066.1 - 0.0016 18.9 0.0 0.0032 17.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 EIW86066.1 - 0.0029 16.7 0.0 0.0053 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_13 PF13166.1 EIW86066.1 - 0.012 14.0 0.0 0.019 13.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EIW86066.1 - 0.045 12.6 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_23 PF13476.1 EIW86066.1 - 0.05 13.9 0.2 0.11 12.8 0.2 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIW86066.1 - 0.053 13.0 0.0 0.14 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain IIGP PF05049.8 EIW86066.1 - 0.065 12.0 0.1 0.086 11.6 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Ras PF00071.17 EIW86066.1 - 0.098 12.0 0.0 0.18 11.1 0.0 1.4 1 0 0 1 1 1 0 Ras family AAA_10 PF12846.2 EIW86066.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Zeta_toxin PF06414.7 EIW86066.1 - 0.14 11.2 0.0 0.27 10.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin MMR_HSR1 PF01926.18 EIW86067.1 - 2.6e-10 40.2 0.0 4.6e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EIW86067.1 - 7.4e-10 38.2 0.0 1e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EIW86067.1 - 0.00013 21.8 0.2 0.00031 20.6 0.1 1.7 2 0 0 2 2 2 1 Dynamin family Miro PF08477.8 EIW86067.1 - 0.00032 21.1 0.0 0.00065 20.1 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 EIW86067.1 - 0.00073 19.8 0.1 0.0027 17.9 0.1 1.8 2 0 0 2 2 2 1 ABC transporter DUF258 PF03193.11 EIW86067.1 - 0.00079 18.6 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EIW86067.1 - 0.0013 18.2 0.1 0.024 14.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EIW86067.1 - 0.0028 17.6 0.0 0.0038 17.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain IIGP PF05049.8 EIW86067.1 - 0.015 14.1 0.1 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_10 PF12846.2 EIW86067.1 - 0.022 14.2 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain DUF815 PF05673.8 EIW86067.1 - 0.025 13.4 0.0 0.042 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_23 PF13476.1 EIW86067.1 - 0.03 14.6 0.1 0.065 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EIW86067.1 - 0.031 13.7 0.1 0.055 12.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EIW86067.1 - 0.04 12.9 0.0 0.099 11.7 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.1 EIW86067.1 - 0.066 13.3 0.1 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ras PF00071.17 EIW86067.1 - 0.093 12.1 0.1 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Ras family Septin PF00735.13 EIW86067.1 - 0.1 11.6 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_13 PF13166.1 EIW86067.1 - 0.23 9.8 0.2 0.64 8.4 0.1 1.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EIW86068.1 - 4.2e-14 52.4 0.0 5.4e-14 52.1 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIW86068.1 - 1.4e-07 30.8 0.0 1.9e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EIW86068.1 - 2.7e-06 26.6 0.0 3.5e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Ras PF00071.17 EIW86068.1 - 4e-06 26.3 0.0 8.7e-06 25.2 0.0 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EIW86068.1 - 2.7e-05 24.6 0.0 6e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EIW86068.1 - 0.0004 20.4 0.1 0.00073 19.5 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_10 PF12846.2 EIW86068.1 - 0.00085 18.8 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain FeoB_N PF02421.13 EIW86068.1 - 0.0014 17.9 0.0 0.0017 17.6 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 EIW86068.1 - 0.0021 18.1 0.0 0.0037 17.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW86068.1 - 0.0026 18.5 0.1 0.0039 18.0 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EIW86068.1 - 0.0065 16.7 0.0 0.0093 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIW86068.1 - 0.0067 16.7 0.1 0.011 16.0 0.1 1.4 1 1 0 1 1 1 1 ABC transporter DUF815 PF05673.8 EIW86068.1 - 0.017 14.0 0.0 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SRPRB PF09439.5 EIW86068.1 - 0.024 13.8 0.0 0.036 13.2 0.0 1.5 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 EIW86068.1 - 0.025 14.1 0.0 0.31 10.5 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.13 EIW86068.1 - 0.027 13.9 0.1 0.055 12.9 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 EIW86068.1 - 0.031 13.7 0.0 0.062 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Septin PF00735.13 EIW86068.1 - 0.032 13.2 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Septin RNA_helicase PF00910.17 EIW86068.1 - 0.043 13.9 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 EIW86068.1 - 0.051 12.9 0.1 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF87 PF01935.12 EIW86068.1 - 0.052 13.3 0.0 0.09 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 IIGP PF05049.8 EIW86068.1 - 0.072 11.8 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.18 EIW86068.1 - 0.11 12.3 0.4 0.42 10.4 0.3 1.8 1 1 0 2 2 2 0 Dynamin family Gtr1_RagA PF04670.7 EIW86068.1 - 0.12 11.5 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_24 PF13479.1 EIW86068.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AIG1 PF04548.11 EIW86069.1 - 7.7e-10 38.2 0.0 1.1e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 EIW86069.1 - 9.1e-10 38.5 0.0 1.6e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIW86069.1 - 5.9e-05 23.5 0.0 0.0001 22.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EIW86069.1 - 0.00043 20.1 0.9 0.0066 16.2 0.1 2.4 2 1 0 3 3 3 1 Dynamin family DUF258 PF03193.11 EIW86069.1 - 0.0018 17.5 0.0 0.0028 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EIW86069.1 - 0.0037 17.5 0.1 0.0056 16.9 0.1 1.7 1 1 0 1 1 1 1 ABC transporter AAA_13 PF13166.1 EIW86069.1 - 0.005 15.3 0.0 0.0079 14.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain Ras PF00071.17 EIW86069.1 - 0.0077 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Ras family AAA_17 PF13207.1 EIW86069.1 - 0.033 15.0 0.1 0.044 14.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EIW86069.1 - 0.043 13.2 0.1 0.16 11.3 0.1 1.7 2 0 0 2 2 2 0 AAA-like domain AAA_29 PF13555.1 EIW86069.1 - 0.052 13.0 0.2 0.21 11.1 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain FeoB_N PF02421.13 EIW86069.1 - 0.069 12.4 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B DUF815 PF05673.8 EIW86069.1 - 0.076 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_23 PF13476.1 EIW86069.1 - 0.13 12.6 0.4 0.27 11.5 0.2 1.5 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EIW86069.1 - 0.14 12.2 0.0 0.4 10.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EIW86069.1 - 0.16 12.1 0.1 1.5 9.0 0.0 2.5 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EIW86070.1 - 1.8e-13 50.4 0.0 2.5e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIW86070.1 - 2.4e-07 30.0 0.0 3.3e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EIW86070.1 - 4.9e-07 29.0 0.0 5.8e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 AIG1 family Ras PF00071.17 EIW86070.1 - 4e-06 26.3 0.0 2.1e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EIW86070.1 - 2.6e-05 24.6 0.0 5.9e-05 23.5 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 EIW86070.1 - 0.00043 19.6 0.0 0.00051 19.3 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.22 EIW86070.1 - 0.00065 20.0 0.1 0.0015 18.8 0.1 1.5 1 1 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EIW86070.1 - 0.0034 17.5 0.0 0.0058 16.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain IIGP PF05049.8 EIW86070.1 - 0.0037 16.1 0.1 0.0047 15.7 0.0 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) AAA_17 PF13207.1 EIW86070.1 - 0.0045 17.7 0.1 0.0091 16.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW86070.1 - 0.0061 16.5 0.0 0.013 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Dynamin_N PF00350.18 EIW86070.1 - 0.0095 15.7 0.3 0.062 13.1 0.2 1.9 1 1 0 2 2 2 1 Dynamin family Septin PF00735.13 EIW86070.1 - 0.017 14.1 0.0 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_10 PF12846.2 EIW86070.1 - 0.022 14.2 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_18 PF13238.1 EIW86070.1 - 0.038 14.3 0.1 0.069 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIW86070.1 - 0.043 13.3 0.1 0.095 12.2 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 EIW86070.1 - 0.069 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EIW86070.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase WD40 PF00400.27 EIW86071.1 - 3.4e-06 26.7 0.0 0.31 10.9 0.0 5.8 6 0 0 6 6 6 1 WD domain, G-beta repeat Clathrin_propel PF01394.15 EIW86071.1 - 0.051 13.8 0.0 0.28 11.5 0.0 2.3 2 0 0 2 2 2 0 Clathrin propeller repeat Apc4_WD40 PF12894.2 EIW86071.1 - 0.066 12.7 0.0 20 4.8 0.0 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF2415 PF10313.4 EIW86071.1 - 0.096 12.3 0.0 0.44 10.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) SPO22 PF08631.5 EIW86072.1 - 1.5e-11 43.8 0.3 1.5e-11 43.8 0.2 2.6 3 1 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like Cyclin PF08613.6 EIW86074.1 - 6.5e-18 65.5 0.0 1.4e-17 64.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EIW86074.1 - 2e-08 33.8 0.0 3.6e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cullin PF00888.17 EIW86076.1 - 2.4e-110 369.8 2.9 3.8e-110 369.1 2.0 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EIW86076.1 - 5.5e-25 86.9 0.8 1.5e-24 85.5 0.5 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain WD40 PF00400.27 EIW86077.1 - 1.7e-10 40.3 5.9 0.014 15.2 0.0 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat Chs3p PF12271.3 EIW86078.1 - 1.7e-115 385.0 22.5 1.9e-115 384.8 15.6 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Amidase PF01425.16 EIW86079.1 - 1.1e-08 34.3 0.0 1.2e-08 34.2 0.0 1.0 1 0 0 1 1 1 1 Amidase F-box-like PF12937.2 EIW86081.1 - 0.00072 19.2 0.7 0.0017 18.0 0.0 2.0 2 1 0 2 2 2 1 F-box-like G-alpha PF00503.15 EIW86083.1 - 1.5e-110 369.5 0.6 2e-110 369.1 0.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIW86083.1 - 7.4e-13 48.0 4.2 1.1e-08 34.4 0.4 3.0 2 2 1 3 3 3 2 ADP-ribosylation factor family Miro PF08477.8 EIW86083.1 - 0.0002 21.8 0.1 0.24 11.8 0.0 2.6 2 1 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EIW86083.1 - 0.0013 18.6 0.0 0.78 9.7 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIW86083.1 - 0.012 15.0 0.1 5.4 6.4 0.0 2.7 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EIW86083.1 - 0.017 14.2 4.6 0.41 9.7 0.1 2.7 2 1 1 3 3 3 0 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EIW86083.1 - 0.059 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF3752 PF12572.3 EIW86084.1 - 1.6e-34 119.2 8.6 1.6e-34 119.2 6.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF3752) F-box-like PF12937.2 EIW86085.1 - 2.4e-06 27.1 0.0 6.1e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW86085.1 - 0.036 13.7 0.0 0.8 9.4 0.0 2.7 2 0 0 2 2 2 0 F-box domain tRNA_bind_2 PF13725.1 EIW86085.1 - 0.13 12.3 0.0 15 5.7 0.0 2.5 2 0 0 2 2 2 0 Possible tRNA binding domain GMC_oxred_C PF05199.8 EIW86086.1 - 2.6e-22 79.6 0.0 6.7e-22 78.3 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EIW86086.1 - 5e-18 65.2 0.0 1.1e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EIW86086.1 - 3.5e-10 39.3 0.0 3.9e-05 22.7 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EIW86086.1 - 5.3e-07 28.8 0.2 4.4e-05 22.4 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EIW86086.1 - 1.5e-05 24.9 0.3 6.4e-05 22.9 0.2 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EIW86086.1 - 2.9e-05 23.3 0.0 0.00037 19.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EIW86086.1 - 5.9e-05 21.7 0.1 0.00018 20.1 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.14 EIW86086.1 - 0.00013 21.2 0.6 0.00031 19.9 0.5 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EIW86086.1 - 0.00021 21.2 0.0 0.00037 20.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW86086.1 - 0.00028 20.0 0.7 0.0018 17.4 0.2 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 EIW86086.1 - 0.00099 19.2 0.1 0.0059 16.6 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIW86086.1 - 0.12 11.2 0.7 0.21 10.4 0.2 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A p450 PF00067.17 EIW86087.1 - 9.3e-71 238.7 0.0 1.1e-70 238.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HTH_41 PF14502.1 EIW86087.1 - 0.013 15.0 0.0 0.043 13.4 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain Med21 PF11221.3 EIW86088.1 - 4.2e-26 91.6 8.8 4.8e-26 91.4 6.1 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Peptidase_C41 PF05417.6 EIW86088.1 - 0.044 13.3 0.0 0.05 13.1 0.0 1.1 1 0 0 1 1 1 0 Hepatitis E cysteine protease Cep57_MT_bd PF06657.8 EIW86088.1 - 0.046 13.6 8.2 0.49 10.3 0.9 3.1 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Intein_splicing PF14890.1 EIW86088.1 - 0.05 12.4 0.3 0.056 12.3 0.2 1.1 1 0 0 1 1 1 0 Intein splicing domain DUF1192 PF06698.6 EIW86088.1 - 0.088 12.6 3.2 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Rogdi_lz PF10259.4 EIW86088.1 - 0.18 10.8 2.2 0.19 10.7 1.5 1.1 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein Pkip-1 PF06878.6 EIW86088.1 - 0.21 11.4 2.7 5.9 6.7 0.2 2.0 2 0 0 2 2 2 0 Pkip-1 protein DUF3391 PF11871.3 EIW86088.1 - 0.35 11.0 3.9 0.88 9.7 2.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) AAA_23 PF13476.1 EIW86088.1 - 0.35 11.1 5.5 0.48 10.7 3.8 1.1 1 0 0 1 1 1 0 AAA domain PRA-PH PF01503.12 EIW86088.1 - 0.54 10.5 3.1 0.45 10.8 0.9 1.8 2 1 0 2 2 2 0 Phosphoribosyl-ATP pyrophosphohydrolase Enkurin PF13864.1 EIW86088.1 - 0.57 10.4 7.2 2.7 8.2 3.4 2.6 1 1 1 2 2 2 0 Calmodulin-binding WXG100 PF06013.7 EIW86088.1 - 0.67 9.9 5.9 3.7 7.6 1.1 2.3 2 0 0 2 2 2 0 Proteins of 100 residues with WXG Snapin_Pallidin PF14712.1 EIW86088.1 - 0.86 9.9 6.4 0.75 10.1 1.3 2.1 2 0 0 2 2 2 0 Snapin/Pallidin CorA PF01544.13 EIW86088.1 - 0.95 8.4 4.1 7.7 5.4 0.1 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein YbaB_DNA_bd PF02575.11 EIW86088.1 - 3.8 7.4 6.5 14 5.6 0.8 2.5 2 1 0 2 2 2 0 YbaB/EbfC DNA-binding family Rtf2 PF04641.7 EIW86089.1 - 1.2e-72 244.2 0.4 1.5e-72 243.9 0.3 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.3 EIW86089.1 - 0.00024 20.5 0.3 0.068 12.7 0.0 2.4 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EIW86089.1 - 0.0036 16.9 0.1 0.046 13.4 0.0 2.4 1 1 1 2 2 2 1 RING-type zinc-finger ANATO PF01821.13 EIW86090.1 - 0.15 12.1 1.2 0.22 11.6 0.8 1.4 1 0 0 1 1 1 0 Anaphylotoxin-like domain RRM_1 PF00076.17 EIW86094.1 - 1.9e-10 40.2 0.0 2.8e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW86094.1 - 1.3e-08 34.6 0.0 2.1e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW86094.1 - 0.00016 21.4 0.0 0.00026 20.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MMR_HSR1 PF01926.18 EIW86101.1 - 4.9e-13 49.0 0.0 8e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIW86101.1 - 7.1e-08 31.8 0.0 1.2e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EIW86101.1 - 1.6e-05 24.0 0.1 2.1e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EIW86101.1 - 5e-05 23.7 0.0 0.00011 22.6 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein Ras PF00071.17 EIW86101.1 - 6.8e-05 22.3 0.0 0.00012 21.5 0.0 1.5 1 1 0 1 1 1 1 Ras family ABC_tran PF00005.22 EIW86101.1 - 0.00087 19.5 0.0 0.0015 18.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EIW86101.1 - 0.0012 18.8 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain IIGP PF05049.8 EIW86101.1 - 0.0015 17.4 0.1 0.0021 16.9 0.1 1.1 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FeoB_N PF02421.13 EIW86101.1 - 0.002 17.4 0.0 0.0026 17.0 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.1 EIW86101.1 - 0.007 16.5 0.1 0.023 14.8 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EIW86101.1 - 0.014 14.8 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 EIW86101.1 - 0.021 14.3 0.1 0.046 13.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EIW86101.1 - 0.025 15.3 0.0 0.038 14.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.8 EIW86101.1 - 0.026 13.4 0.0 0.048 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Septin PF00735.13 EIW86101.1 - 0.031 13.2 0.0 0.047 12.7 0.0 1.2 1 0 0 1 1 1 0 Septin Dynamin_N PF00350.18 EIW86101.1 - 0.033 14.0 0.5 0.23 11.2 0.4 2.0 1 1 1 2 2 2 0 Dynamin family AAA_24 PF13479.1 EIW86101.1 - 0.054 13.0 0.0 0.091 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EIW86101.1 - 0.1 12.7 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.18 EIW86102.1 - 4.2e-10 39.6 0.0 7.7e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EIW86102.1 - 5.7e-10 38.6 0.0 8.3e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EIW86102.1 - 7.8e-05 23.1 0.0 0.00014 22.3 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EIW86102.1 - 8.8e-05 22.3 1.0 0.0015 18.4 0.1 2.4 2 1 1 3 3 3 1 Dynamin family DUF258 PF03193.11 EIW86102.1 - 0.0006 19.0 0.0 0.00096 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EIW86102.1 - 0.0019 18.4 0.2 0.0031 17.7 0.1 1.7 1 1 0 1 1 1 1 ABC transporter Ras PF00071.17 EIW86102.1 - 0.0028 17.0 0.0 0.0046 16.3 0.0 1.4 1 0 0 1 1 1 1 Ras family AAA_13 PF13166.1 EIW86102.1 - 0.0068 14.9 0.0 0.011 14.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EIW86102.1 - 0.013 14.9 0.1 0.078 12.3 0.1 1.9 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 EIW86102.1 - 0.014 16.2 0.1 0.035 14.9 0.0 1.7 1 1 0 2 2 2 0 AAA domain FeoB_N PF02421.13 EIW86102.1 - 0.028 13.6 0.0 0.039 13.2 0.0 1.2 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.1 EIW86102.1 - 0.038 13.5 0.0 0.18 11.3 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain DUF815 PF05673.8 EIW86102.1 - 0.051 12.4 0.1 0.079 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.1 EIW86102.1 - 0.1 12.4 0.0 0.5 10.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EIW86102.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EIW86102.1 - 0.13 12.5 0.6 0.31 11.3 0.3 1.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EIW86102.1 - 0.15 12.2 0.1 2.1 8.5 0.0 2.4 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) DARPP-32 PF05395.7 EIW86105.1 - 0.16 12.1 5.0 0.27 11.4 3.5 1.4 1 0 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 Arena_RNA_pol PF06317.6 EIW86108.1 - 0.014 12.0 1.0 0.019 11.5 0.7 1.0 1 0 0 1 1 1 0 Arenavirus RNA polymerase Uds1 PF15456.1 EIW86108.1 - 1.1 9.2 12.7 0.032 14.2 2.7 2.6 2 1 0 2 2 2 0 Up-regulated During Septation MMR_HSR1 PF01926.18 EIW86109.1 - 1.1e-12 47.9 0.0 1.6e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIW86109.1 - 1.4e-07 30.8 0.0 2e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Ras PF00071.17 EIW86109.1 - 6.9e-07 28.7 0.1 3.9e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 Ras family AIG1 PF04548.11 EIW86109.1 - 1.7e-06 27.3 0.0 1.9e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EIW86109.1 - 4e-05 24.0 0.0 0.0001 22.7 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein AAA_17 PF13207.1 EIW86109.1 - 0.00059 20.6 0.2 0.0012 19.6 0.1 1.7 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EIW86109.1 - 0.00095 18.4 0.1 0.0012 18.1 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.1 EIW86109.1 - 0.0016 18.4 0.0 0.0042 17.1 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EIW86109.1 - 0.0018 18.3 0.0 0.0029 17.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIW86109.1 - 0.0044 17.3 0.1 0.012 15.8 0.0 1.6 1 1 0 1 1 1 1 ABC transporter AAA_10 PF12846.2 EIW86109.1 - 0.011 15.1 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Septin PF00735.13 EIW86109.1 - 0.019 13.9 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 Septin AAA_18 PF13238.1 EIW86109.1 - 0.024 14.9 0.1 0.044 14.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EIW86109.1 - 0.041 13.4 0.0 0.05 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EIW86109.1 - 0.044 13.9 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 EIW86109.1 - 0.056 12.9 0.1 0.12 11.9 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.5 EIW86109.1 - 0.063 12.5 0.1 0.31 10.2 0.1 2.0 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 EIW86109.1 - 0.075 12.5 0.1 0.24 10.9 0.0 1.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein IIGP PF05049.8 EIW86109.1 - 0.076 11.8 0.0 0.099 11.4 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.18 EIW86109.1 - 0.094 12.5 0.4 0.87 9.3 0.3 2.2 1 1 1 2 2 2 0 Dynamin family DUF815 PF05673.8 EIW86109.1 - 0.1 11.5 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AIG1 PF04548.11 EIW86110.1 - 8.5e-08 31.5 0.0 1.2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 EIW86110.1 - 2.3e-07 30.7 0.0 4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EIW86110.1 - 0.00046 20.5 0.0 0.002 18.4 0.0 2.2 2 1 0 2 2 2 1 ABC transporter Dynamin_N PF00350.18 EIW86110.1 - 0.00084 19.1 0.3 0.0052 16.6 0.1 2.1 1 1 1 2 2 2 1 Dynamin family DUF258 PF03193.11 EIW86110.1 - 0.0024 17.0 0.0 0.004 16.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EIW86110.1 - 0.0091 16.4 0.0 0.017 15.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein DUF815 PF05673.8 EIW86110.1 - 0.047 12.6 0.0 0.076 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Ras PF00071.17 EIW86110.1 - 0.047 13.0 0.0 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 Ras family AAA_29 PF13555.1 EIW86110.1 - 0.051 13.1 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EIW86110.1 - 0.087 13.1 0.1 0.18 12.1 0.1 1.5 1 0 0 1 1 1 0 AAA domain IIGP PF05049.8 EIW86110.1 - 0.13 11.0 0.1 0.17 10.6 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Zeta_toxin PF06414.7 EIW86110.1 - 0.14 11.2 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_10 PF12846.2 EIW86110.1 - 0.19 11.1 0.3 0.36 10.2 0.1 1.4 1 1 0 1 1 1 0 AAA-like domain AIG1 PF04548.11 EIW86111.1 - 3.1e-09 36.2 0.0 4.1e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 EIW86111.1 - 2.3e-07 30.7 0.0 3.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EIW86111.1 - 9.5e-06 26.1 0.0 1.4e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Dynamin_N PF00350.18 EIW86111.1 - 0.00023 21.0 0.3 0.00085 19.1 0.1 1.8 1 1 1 2 2 2 1 Dynamin family ABC_tran PF00005.22 EIW86111.1 - 0.0043 17.3 0.0 0.01 16.1 0.0 1.6 2 0 0 2 2 2 1 ABC transporter Ras PF00071.17 EIW86111.1 - 0.0053 16.1 0.0 0.012 15.0 0.0 1.5 2 0 0 2 2 2 1 Ras family DUF258 PF03193.11 EIW86111.1 - 0.011 14.9 0.1 0.017 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF2802 PF10975.3 EIW86111.1 - 0.012 15.3 0.1 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) AAA_10 PF12846.2 EIW86111.1 - 0.021 14.3 0.3 0.088 12.2 0.1 1.8 1 1 1 2 2 2 0 AAA-like domain AAA_29 PF13555.1 EIW86111.1 - 0.029 13.8 0.1 0.15 11.6 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain IIGP PF05049.8 EIW86111.1 - 0.061 12.1 0.1 0.081 11.7 0.1 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_16 PF13191.1 EIW86111.1 - 0.065 13.2 0.1 0.16 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 EIW86111.1 - 0.068 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_22 PF13401.1 EIW86111.1 - 0.13 12.4 0.0 0.24 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EIW86111.1 - 0.18 12.1 0.1 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF1289 PF06945.8 EIW86112.1 - 0.13 11.7 0.4 0.28 10.7 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) ORC5_C PF14630.1 EIW86115.1 - 1.7e-47 162.1 0.0 3.2e-47 161.2 0.0 1.5 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus F-box-like PF12937.2 EIW86116.1 - 0.072 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 F-box-like NACHT PF05729.7 EIW86118.1 - 1.3e-10 41.1 0.0 2.7e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EIW86118.1 - 6.8e-09 35.9 0.1 1.5e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW86118.1 - 1.7e-05 24.9 0.0 6.1e-05 23.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EIW86118.1 - 0.00016 21.7 0.0 0.003 17.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase APS_kinase PF01583.15 EIW86118.1 - 0.00017 21.2 0.1 0.00039 20.0 0.0 1.6 1 0 0 1 1 1 1 Adenylylsulphate kinase Arch_ATPase PF01637.13 EIW86118.1 - 0.00017 21.3 0.0 0.00026 20.7 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase PIF1 PF05970.9 EIW86118.1 - 0.002 17.1 0.0 0.0032 16.4 0.0 1.2 1 0 0 1 1 1 1 PIF1-like helicase AAA_18 PF13238.1 EIW86118.1 - 0.0021 18.3 0.0 0.0043 17.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EIW86118.1 - 0.0027 18.0 0.0 0.0071 16.6 0.0 1.7 2 0 0 2 2 1 1 ABC transporter UPF0079 PF02367.12 EIW86118.1 - 0.0037 16.9 0.0 0.0067 16.0 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activ_2 PF14532.1 EIW86118.1 - 0.0059 16.6 0.0 0.036 14.1 0.0 2.1 2 0 0 2 2 2 1 Sigma-54 interaction domain ArgK PF03308.11 EIW86118.1 - 0.0064 15.2 0.0 0.0098 14.6 0.0 1.2 1 0 0 1 1 1 1 ArgK protein Zeta_toxin PF06414.7 EIW86118.1 - 0.0089 15.1 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.1 EIW86118.1 - 0.023 14.4 0.0 0.071 12.8 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 EIW86118.1 - 0.024 15.4 0.0 0.047 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EIW86118.1 - 0.025 14.1 0.0 0.055 13.0 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain KAP_NTPase PF07693.9 EIW86118.1 - 0.03 13.3 0.1 1.2 7.9 0.0 2.2 1 1 0 2 2 2 0 KAP family P-loop domain T2SE PF00437.15 EIW86118.1 - 0.031 13.2 0.0 0.051 12.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 EIW86118.1 - 0.035 14.3 0.0 0.2 11.8 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EIW86118.1 - 0.04 12.7 0.0 0.12 11.2 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain DUF2075 PF09848.4 EIW86118.1 - 0.041 12.8 0.0 0.064 12.2 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_30 PF13604.1 EIW86118.1 - 0.048 13.2 0.0 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 EIW86118.1 - 0.065 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family DUF2791 PF10923.3 EIW86118.1 - 0.083 11.4 0.0 0.13 10.8 0.0 1.2 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) TIP49 PF06068.8 EIW86118.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_33 PF13671.1 EIW86118.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EIW86118.1 - 0.17 11.1 0.0 0.37 9.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein KTI12 PF08433.5 EIW86118.1 - 0.18 10.9 0.0 0.31 10.2 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MMR_HSR1 PF01926.18 EIW86121.1 - 3.3e-09 36.7 0.0 5.4e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EIW86121.1 - 4.3e-07 29.2 0.0 5.8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 AIG1 family DUF258 PF03193.11 EIW86121.1 - 0.0002 20.5 0.0 0.00036 19.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EIW86121.1 - 0.001 19.3 0.9 0.002 18.3 0.6 1.9 1 1 0 1 1 1 1 ABC transporter Dynamin_N PF00350.18 EIW86121.1 - 0.0013 18.5 0.4 0.0024 17.7 0.1 1.5 2 0 0 2 2 2 1 Dynamin family AAA_29 PF13555.1 EIW86121.1 - 0.0079 15.6 0.3 0.082 12.4 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.8 EIW86121.1 - 0.021 13.7 0.1 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.7 EIW86121.1 - 0.036 13.1 0.1 0.054 12.5 0.1 1.3 1 0 0 1 1 1 0 Zeta toxin IIGP PF05049.8 EIW86121.1 - 0.047 12.5 0.2 0.11 11.2 0.1 1.7 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Miro PF08477.8 EIW86121.1 - 0.051 14.0 0.0 0.13 12.8 0.0 1.8 2 0 0 2 2 2 0 Miro-like protein AAA_16 PF13191.1 EIW86121.1 - 0.06 13.3 0.0 0.082 12.8 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 EIW86121.1 - 0.063 13.6 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain Arf PF00025.16 EIW86121.1 - 0.071 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family RNA_helicase PF00910.17 EIW86121.1 - 0.1 12.7 0.1 0.46 10.6 0.1 2.0 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.1 EIW86121.1 - 0.13 12.4 0.0 0.42 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EIW86121.1 - 0.15 11.5 0.1 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain F-box-like PF12937.2 EIW86122.1 - 0.004 16.8 0.1 0.05 13.3 0.0 2.6 2 0 0 2 2 2 1 F-box-like Thaumatin PF00314.12 EIW86123.1 - 1.5e-08 34.3 9.2 1.5e-07 31.1 6.3 2.1 1 1 0 1 1 1 1 Thaumatin family Porin_4 PF13609.1 EIW86123.1 - 0.0014 18.2 1.8 0.0014 18.2 1.2 1.6 2 0 0 2 2 2 1 Gram-negative porin DHC_N1 PF08385.7 EIW86124.1 - 2.1e-188 627.3 0.1 1.2e-186 621.6 0.0 2.7 3 0 0 3 3 3 2 Dynein heavy chain, N-terminal region 1 TORC_C PF12886.2 EIW86124.1 - 0.075 13.2 0.0 0.29 11.3 0.0 2.0 1 0 0 1 1 1 0 Transducer of regulated CREB activity, C terminus ChaC PF04752.7 EIW86125.1 - 2.6e-52 177.3 0.0 3e-52 177.1 0.0 1.0 1 0 0 1 1 1 1 ChaC-like protein AIG2 PF06094.7 EIW86125.1 - 0.018 15.5 0.1 0.051 14.0 0.1 1.8 1 1 0 1 1 1 0 AIG2-like family Toxin_14 PF07829.6 EIW86125.1 - 0.076 12.7 1.7 0.14 11.9 1.2 1.3 1 0 0 1 1 1 0 Alpha-A conotoxin PIVA-like protein DUF4038 PF13204.1 EIW86125.1 - 0.1 11.9 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) adh_short PF00106.20 EIW86126.1 - 4.4e-19 69.0 5.4 7.8e-17 61.6 3.8 2.2 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EIW86126.1 - 5.3e-15 55.5 2.9 1.7e-12 47.3 2.0 2.1 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EIW86126.1 - 0.00061 19.6 0.6 0.0065 16.2 0.4 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EIW86126.1 - 0.00096 19.2 0.1 0.0017 18.4 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EIW86126.1 - 0.00098 19.1 0.2 0.0027 17.7 0.2 1.8 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EIW86126.1 - 0.0022 17.0 0.1 0.006 15.6 0.0 1.7 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EIW86126.1 - 0.0067 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 EIW86126.1 - 0.013 14.7 0.0 0.024 13.8 0.0 1.4 2 0 0 2 2 2 0 NmrA-like family Epimerase PF01370.16 EIW86126.1 - 0.021 14.2 0.0 0.49 9.7 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EIW86126.1 - 0.05 13.2 0.2 0.075 12.6 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 EIW86126.1 - 0.16 11.7 0.1 0.39 10.5 0.1 1.6 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Wzy_C PF04932.10 EIW86127.1 - 5 6.8 12.2 3.7e+02 0.8 8.4 2.8 1 1 0 1 1 1 0 O-Antigen ligase Thaumatin PF00314.12 EIW86129.1 - 1.5e-08 34.3 9.2 1.5e-07 31.1 6.3 2.1 1 1 0 1 1 1 1 Thaumatin family Porin_4 PF13609.1 EIW86129.1 - 0.0014 18.2 1.8 0.0014 18.2 1.2 1.6 2 0 0 2 2 2 1 Gram-negative porin Baculo_11_kDa PF06143.6 EIW86130.1 - 0.6 9.5 3.6 0.26 10.6 0.3 2.0 2 0 0 2 2 2 0 Baculovirus 11 kDa family Aminotran_5 PF00266.14 EIW86131.1 - 1.5e-13 50.2 0.0 2.2e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EIW86131.1 - 0.00025 20.1 0.2 0.0018 17.3 0.0 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EIW86131.1 - 0.00098 18.1 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Extensin_2 PF04554.8 EIW86131.1 - 0.043 13.6 8.1 1.7 8.5 1.5 2.4 2 0 0 2 2 2 0 Extensin-like region Clathrin PF00637.15 EIW86132.1 - 4.9e-14 52.1 0.0 0.00022 20.8 0.0 3.7 3 1 0 3 3 3 3 Region in Clathrin and VPS VPS11_C PF12451.3 EIW86132.1 - 1.6e-05 24.6 0.0 3.4e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 11 C terminal Apc4_WD40 PF12894.2 EIW86132.1 - 0.032 13.7 0.0 0.076 12.5 0.0 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain zf-C3HC4_2 PF13923.1 EIW86132.1 - 0.18 11.8 8.1 0.31 11.0 5.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW86132.1 - 0.35 10.7 8.7 0.66 9.8 6.0 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 EIW86132.1 - 0.51 10.1 9.2 0.82 9.4 6.4 1.3 1 0 0 1 1 1 0 zinc-RING finger domain ADH_zinc_N PF00107.21 EIW86133.1 - 3.9e-18 65.2 0.0 5.4e-18 64.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW86133.1 - 4.1e-06 27.6 0.0 7.9e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EIW86134.1 - 6.2e-23 80.7 0.2 8.5e-23 80.3 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW86134.1 - 6e-07 30.4 0.0 1.4e-06 29.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NMO PF03060.10 EIW86134.1 - 0.0065 15.6 0.0 0.0091 15.1 0.0 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ELFV_dehydrog PF00208.16 EIW86134.1 - 0.0073 15.9 0.8 0.022 14.3 0.1 1.8 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.13 EIW86134.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain 2-Hacid_dh_C PF02826.14 EIW86134.1 - 0.14 11.3 0.1 0.21 10.7 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SNARE_assoc PF09335.6 EIW86136.1 - 0.051 13.7 0.0 0.086 13.0 0.0 1.2 1 0 0 1 1 1 0 SNARE associated Golgi protein DUF912 PF06024.7 EIW86136.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2101 PF09874.4 EIW86138.1 - 0.98 8.8 13.3 0.065 12.7 4.9 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) GH3 PF03321.8 EIW86139.1 - 1.7e-39 135.7 0.0 2.8e-39 135.0 0.0 1.3 1 1 0 1 1 1 1 GH3 auxin-responsive promoter SLAC1 PF03595.12 EIW86140.1 - 0.07 11.7 0.6 0.075 11.6 0.4 1.1 1 0 0 1 1 1 0 Voltage-dependent anion channel AA_permease_2 PF13520.1 EIW86140.1 - 0.091 11.2 0.4 0.1 11.0 0.3 1.0 1 0 0 1 1 1 0 Amino acid permease SLA_LP_auto_ag PF05889.8 EIW86142.1 - 0.039 12.4 0.0 0.059 11.8 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) DUF2666 PF10869.3 EIW86144.1 - 0.036 14.1 0.2 0.072 13.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) HPPK PF01288.15 EIW86144.1 - 0.073 12.8 0.6 0.16 11.6 0.4 1.6 1 0 0 1 1 1 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Nucleoplasmin PF03066.10 EIW86144.1 - 4.8 6.6 9.7 11 5.5 6.7 1.5 1 0 0 1 1 1 0 Nucleoplasmin Dimer_Tnp_hAT PF05699.9 EIW86145.1 - 2.5e-15 55.8 0.1 2.9e-15 55.6 0.1 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region F-box-like PF12937.2 EIW86146.1 - 0.00049 19.7 0.1 0.0039 16.8 0.0 2.6 2 0 0 2 2 2 1 F-box-like Aminotran_4 PF01063.14 EIW86147.1 - 8.1e-20 71.2 0.0 1.8e-19 70.1 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class IV tRNA_U5-meth_tr PF05958.6 EIW86148.1 - 3e-11 42.6 0.0 3.4e-06 26.0 0.0 2.4 3 0 0 3 3 3 2 tRNA (Uracil-5-)-methyltransferase Methyltransf_26 PF13659.1 EIW86148.1 - 0.0001 22.3 0.1 0.00028 20.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EIW86148.1 - 0.00025 20.2 0.0 0.00042 19.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EIW86148.1 - 0.0021 18.6 0.0 0.0048 17.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EIW86148.1 - 0.0044 16.5 0.0 0.0067 15.9 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_31 PF13847.1 EIW86148.1 - 0.012 15.2 0.0 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TRAM PF01938.15 EIW86148.1 - 0.039 13.7 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 TRAM domain TPMT PF05724.6 EIW86148.1 - 0.072 12.5 0.2 0.14 11.5 0.0 1.5 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) UPF0020 PF01170.13 EIW86148.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 COX16 PF14138.1 EIW86149.1 - 4.6e-27 93.9 0.0 6.1e-27 93.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 DUF21 PF01595.15 EIW86152.1 - 1.2e-27 96.3 0.3 1.9e-27 95.7 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EIW86152.1 - 3.6e-06 26.6 0.1 0.06 13.1 0.0 3.0 3 0 0 3 3 3 2 CBS domain DUF21 PF01595.15 EIW86153.1 - 4e-23 81.6 5.4 2.8e-22 78.8 3.7 2.0 1 1 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EIW86153.1 - 5.6e-06 26.0 0.1 0.021 14.5 0.0 2.5 2 0 0 2 2 2 2 CBS domain Alpha-amylase PF00128.19 EIW86154.1 - 2.4e-45 155.2 0.0 3.3e-45 154.8 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EIW86154.1 - 8.6e-13 48.1 0.0 2e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Glyco_transf_25 PF01755.12 EIW86155.1 - 3.7e-10 39.8 0.0 5.9e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) E3_binding PF02817.12 EIW86157.1 - 0.087 12.4 0.1 0.17 11.5 0.0 1.5 2 0 0 2 2 2 0 e3 binding domain F-box-like PF12937.2 EIW86158.1 - 0.00017 21.2 0.0 0.00091 18.9 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box-like PF12937.2 EIW86159.1 - 0.011 15.4 0.1 0.043 13.5 0.0 2.1 2 0 0 2 2 2 0 F-box-like F-box-like PF12937.2 EIW86160.1 - 0.003 17.2 0.0 0.066 12.9 0.0 2.7 2 0 0 2 2 2 1 F-box-like DUF4419 PF14388.1 EIW86162.1 - 2.6e-36 125.3 0.0 6.1e-36 124.1 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4419) TMEM220 PF15071.1 EIW86163.1 - 0.2 12.1 2.4 0.22 11.9 0.2 2.2 2 0 0 2 2 2 0 Transmembrane family 220, helix Abhydrolase_9_N PF15420.1 EIW86163.1 - 0.67 9.6 13.9 9.1 5.9 0.0 3.5 3 1 0 4 4 4 0 Alpha/beta-hydrolase family N-terminus zf-C2H2 PF00096.21 EIW86164.1 - 2.5e-07 30.6 5.9 0.00013 22.1 0.2 3.5 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW86164.1 - 1.7e-06 28.0 3.5 1.5e-05 24.9 0.1 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIW86164.1 - 7.4e-06 25.9 3.1 0.045 14.1 0.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2HC_2 PF13913.1 EIW86164.1 - 0.0023 17.5 2.1 0.013 15.1 0.8 2.3 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_jaz PF12171.3 EIW86164.1 - 0.005 16.9 0.3 1.5 9.0 0.0 2.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIW86164.1 - 0.08 13.1 0.5 5.4 7.3 0.0 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.10 EIW86164.1 - 0.88 9.3 4.6 11 5.9 0.2 2.6 1 1 1 2 2 2 0 BED zinc finger Bromodomain PF00439.20 EIW86165.1 - 1.9e-21 75.7 0.0 3.2e-14 52.5 0.0 2.5 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 EIW86165.1 - 2.1e-08 33.9 0.0 4e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 BAH domain SOG2 PF10428.4 EIW86165.1 - 6.9 5.2 10.0 0.26 9.9 1.5 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein YGGT PF02325.12 EIW86166.1 - 0.14 12.1 3.6 0.2 11.6 0.9 2.2 2 0 0 2 2 2 0 YGGT family F-box-like PF12937.2 EIW86167.1 - 0.0032 17.1 0.0 0.014 15.1 0.0 2.1 1 0 0 1 1 1 1 F-box-like F-box-like PF12937.2 EIW86169.1 - 0.04 13.6 0.0 0.13 12.0 0.0 1.9 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.2 EIW86171.1 - 0.0015 18.1 2.7 0.0073 16.0 0.0 3.4 5 0 0 5 5 5 1 F-box-like AAA_18 PF13238.1 EIW86173.1 - 0.00021 21.5 0.1 0.002 18.4 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EIW86173.1 - 0.00026 21.7 0.0 0.0011 19.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW86173.1 - 0.0011 18.8 0.1 0.015 15.1 0.0 2.2 2 1 0 2 2 2 1 AAA domain PRK PF00485.13 EIW86173.1 - 0.022 14.3 0.0 0.05 13.1 0.0 1.6 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 EIW86173.1 - 0.062 12.3 0.2 0.12 11.4 0.1 1.5 2 0 0 2 2 2 0 Zeta toxin NB-ARC PF00931.17 EIW86173.1 - 0.13 11.0 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain ArgK PF03308.11 EIW86173.1 - 0.15 10.8 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Rgp1 PF08737.5 EIW86174.1 - 1e-43 150.0 0.0 2.1e-43 149.0 0.0 1.4 1 0 0 1 1 1 1 Rgp1 Arrestin_C PF02752.17 EIW86174.1 - 0.056 13.5 0.0 23 5.0 0.0 3.0 3 0 0 3 3 3 0 Arrestin (or S-antigen), C-terminal domain Maf_N PF08383.6 EIW86177.1 - 0.15 11.6 2.7 0.61 9.6 0.0 2.8 3 0 0 3 3 3 0 Maf N-terminal region DUF2919 PF11143.3 EIW86180.1 - 0.04 13.7 8.1 0.084 12.7 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) DUF3948 PF13134.1 EIW86180.1 - 0.35 10.3 3.2 0.22 10.9 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3948) Bac_Ubq_Cox PF01654.12 EIW86180.1 - 9.3 4.5 13.3 4.8 5.4 7.0 2.1 2 1 0 2 2 2 0 Bacterial Cytochrome Ubiquinol Oxidase MFS_1 PF07690.11 EIW86181.1 - 1.9e-43 148.5 49.5 3.5e-41 141.1 34.2 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2754 PF10953.3 EIW86181.1 - 0.36 10.9 0.1 0.36 10.9 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2754) PSP1 PF04468.7 EIW86182.1 - 9e-32 108.9 0.8 1.5e-31 108.2 0.5 1.4 1 0 0 1 1 1 1 PSP1 C-terminal conserved region DUF4091 PF13320.1 EIW86183.1 - 0.1 12.5 0.1 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4091) DoxD PF04173.8 EIW86185.1 - 0.54 9.9 6.4 0.31 10.6 0.4 2.4 2 0 0 2 2 2 0 TQO small subunit DoxD PCI PF01399.22 EIW86186.1 - 0.00017 21.8 0.0 0.0003 21.0 0.0 1.4 1 0 0 1 1 1 1 PCI domain Exo_endo_phos PF03372.18 EIW86190.1 - 3.4e-14 53.3 0.4 4.6e-14 52.9 0.3 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIW86190.1 - 2.2e-08 33.7 0.0 4.4e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 EIW86191.1 - 6e-05 22.4 0.0 9.2e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF3042 PF11240.3 EIW86191.1 - 0.082 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) zf-RVT PF13966.1 EIW86192.1 - 0.00051 20.3 0.0 0.0014 18.8 0.0 1.8 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase Peptidase_M28 PF04389.12 EIW86193.1 - 2e-27 96.0 0.0 3.5e-27 95.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EIW86193.1 - 2.2e-08 33.8 0.0 3.2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 EFP PF01132.15 EIW86193.1 - 0.033 13.8 0.4 0.51 10.0 0.1 2.3 1 1 1 2 2 2 0 Elongation factor P (EF-P) OB domain DUF3483 PF11982.3 EIW86194.1 - 0.021 14.0 0.5 0.021 14.0 0.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3483) DUF2518 PF10726.4 EIW86194.1 - 0.14 11.7 2.0 0.38 10.2 1.4 1.7 1 0 0 1 1 1 0 Protein of function (DUF2518) Peptidase_M28 PF04389.12 EIW86195.1 - 1.9e-27 96.1 0.0 3.6e-27 95.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EIW86195.1 - 1.6e-10 40.7 0.1 2.5e-10 40.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 MHC_II_alpha PF00993.15 EIW86195.1 - 0.0068 15.9 0.1 0.014 14.9 0.1 1.5 1 0 0 1 1 1 1 Class II histocompatibility antigen, alpha domain TraE PF05309.6 EIW86196.1 - 0.082 12.0 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 TraE protein Peptidase_M50 PF02163.17 EIW86198.1 - 1.4 7.8 4.0 2.8 6.8 2.8 1.5 1 0 0 1 1 1 0 Peptidase family M50 HTH_29 PF13551.1 EIW86199.1 - 2e-09 37.5 0.2 4.6e-09 36.4 0.0 1.6 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_IS630 PF01710.11 EIW86199.1 - 1.9e-08 33.9 0.0 3.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Transposase HTH_23 PF13384.1 EIW86199.1 - 3.7e-07 29.5 0.0 6.7e-07 28.7 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain PAX PF00292.13 EIW86199.1 - 4.9e-06 26.2 0.0 6.7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 'Paired box' domain HTH_32 PF13565.1 EIW86199.1 - 1.4e-05 25.7 0.0 4.2e-05 24.2 0.0 1.8 1 1 1 2 2 2 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 EIW86199.1 - 6.9e-05 22.7 0.1 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 Transposase DDE_3 PF13358.1 EIW86199.1 - 0.0002 21.1 0.0 0.00033 20.4 0.0 1.6 1 1 0 1 1 1 1 DDE superfamily endonuclease HTH_38 PF13936.1 EIW86199.1 - 0.0058 16.1 0.1 0.0098 15.4 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_33 PF13592.1 EIW86199.1 - 0.0081 15.6 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn helix Sigma70_r4_2 PF08281.7 EIW86199.1 - 0.017 14.5 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_17 PF12728.2 EIW86199.1 - 0.037 14.2 0.0 0.086 13.1 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_28 PF13518.1 EIW86199.1 - 0.041 13.9 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain GerE PF00196.14 EIW86199.1 - 0.048 12.9 0.0 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, luxR family HTH_7 PF02796.10 EIW86199.1 - 0.052 13.4 0.0 0.44 10.4 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain of resolvase P22_Cro PF14549.1 EIW86199.1 - 0.071 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 DNA-binding transcriptional regulator Cro HTH_3 PF01381.17 EIW86199.1 - 0.075 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix DUF3486 PF11985.3 EIW86199.1 - 0.16 12.0 0.9 0.4 10.7 0.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3486) Metal_resist PF13801.1 EIW86200.1 - 1.9 8.4 0.0 1.9 8.4 0.0 2.7 3 0 0 3 3 3 0 Heavy-metal resistance Glypican PF01153.14 EIW86202.1 - 0.072 11.6 0.7 0.077 11.5 0.5 1.0 1 0 0 1 1 1 0 Glypican CDC45 PF02724.9 EIW86202.1 - 0.44 8.5 3.0 0.47 8.4 2.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2890 PF11081.3 EIW86202.1 - 0.61 10.1 3.5 0.71 9.8 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) NOA36 PF06524.7 EIW86202.1 - 2.2 7.4 5.4 2.4 7.3 3.7 1.0 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.4 EIW86202.1 - 5.9 5.5 8.4 6.4 5.3 5.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Hydrophobin PF01185.13 EIW86203.1 - 1.6e-22 79.6 10.3 2e-22 79.4 7.1 1.1 1 0 0 1 1 1 1 Fungal hydrophobin Trp_oprn_chp PF09534.5 EIW86204.1 - 2.6 7.6 8.4 1 8.9 0.9 2.8 3 0 0 3 3 3 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Kdo PF06293.9 EIW86207.1 - 0.001 18.1 0.0 0.0013 17.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF572 PF04502.8 EIW86208.1 - 0.42 9.7 5.7 0.6 9.2 4.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF605 PF04652.11 EIW86208.1 - 6.3 6.0 22.9 9.2 5.5 15.9 1.3 1 0 0 1 1 1 0 Vta1 like Med9 PF07544.8 EIW86209.1 - 1.1e-05 25.0 0.1 1.3e-05 24.8 0.1 1.2 1 0 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 DUF2397 PF09660.5 EIW86209.1 - 0.008 14.8 0.6 0.033 12.7 0.3 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2397) Enkurin PF13864.1 EIW86209.1 - 0.017 15.3 0.1 0.026 14.7 0.1 1.3 1 0 0 1 1 1 0 Calmodulin-binding Lipoprotein_Ltp PF07553.6 EIW86209.1 - 0.066 13.1 1.5 0.12 12.2 0.2 2.2 2 2 0 2 2 2 0 Host cell surface-exposed lipoprotein DUF883 PF05957.8 EIW86209.1 - 0.077 13.4 0.2 0.33 11.3 0.0 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF2569 PF10754.4 EIW86211.1 - 0.03 14.5 0.5 0.03 14.5 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) MIT PF04212.13 EIW86213.1 - 4.4e-14 52.1 0.0 6.4e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Pkinase PF00069.20 EIW86214.1 - 3.1e-22 78.9 0.0 3.6e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW86214.1 - 1.7e-10 40.4 0.0 2e-10 40.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW86214.1 - 0.00073 18.5 0.0 0.00098 18.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like MOZ_SAS PF01853.13 EIW86217.1 - 1.2e-65 220.3 0.1 8.4e-65 217.5 0.0 2.0 2 0 0 2 2 2 1 MOZ/SAS family Tudor-knot PF11717.3 EIW86217.1 - 4.9e-09 35.7 0.0 1.1e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_1 PF00583.19 EIW86217.1 - 0.013 15.5 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-Sec23_Sec24 PF04810.10 EIW86218.1 - 0.061 12.8 0.8 0.061 12.8 0.6 2.5 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger RNase_H PF00075.19 EIW86219.1 - 8.4e-10 39.1 0.0 9.4e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 RNase H DUF3866 PF12982.2 EIW86219.1 - 0.068 12.1 0.0 0.12 11.3 0.0 1.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3866) Ribosomal_L19e PF01280.15 EIW86220.1 - 1.2e-60 203.5 12.2 1.2e-60 203.5 8.5 1.7 2 0 0 2 2 2 1 Ribosomal protein L19e S4 PF01479.20 EIW86220.1 - 0.0023 17.3 0.1 0.0072 15.7 0.0 1.8 1 0 0 1 1 1 1 S4 domain DUF349 PF03993.7 EIW86220.1 - 3.7 7.7 12.3 12 6.0 0.1 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Pkinase PF00069.20 EIW86221.1 - 4.8e-66 222.5 0.0 5.5e-66 222.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW86221.1 - 4.3e-24 84.9 0.0 6e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW86221.1 - 1.9e-05 23.7 0.1 6.3e-05 22.0 0.0 1.9 2 1 0 2 2 2 1 Kinase-like AAA PF00004.24 EIW86222.1 - 2.6e-42 144.1 0.0 4.5e-42 143.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EIW86222.1 - 1.6e-26 91.9 0.8 6.3e-26 90.0 0.3 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EIW86222.1 - 2.4e-20 72.1 1.7 2.4e-20 72.1 1.2 1.8 2 0 0 2 2 1 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 EIW86222.1 - 4.6e-06 26.8 0.8 0.00057 20.0 0.1 2.7 2 1 0 2 2 1 1 AAA domain AAA_5 PF07728.9 EIW86222.1 - 9e-06 25.4 0.0 3.4e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EIW86222.1 - 1.1e-05 25.3 0.1 4.6e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EIW86222.1 - 1.1e-05 24.5 0.0 1.9e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EIW86222.1 - 2.3e-05 25.2 0.0 7.7e-05 23.5 0.0 1.9 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.12 EIW86222.1 - 2.6e-05 23.7 0.0 5.9e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 EIW86222.1 - 8.3e-05 22.6 0.0 0.002 18.1 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 EIW86222.1 - 0.00033 19.4 0.2 0.00098 17.9 0.0 1.7 2 0 0 2 2 2 1 TIP49 C-terminus AAA_33 PF13671.1 EIW86222.1 - 0.0005 19.9 0.0 0.0014 18.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.1 EIW86222.1 - 0.001 18.4 0.2 0.23 10.8 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 EIW86222.1 - 0.0011 19.2 0.2 0.0078 16.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EIW86222.1 - 0.0023 18.1 0.0 0.009 16.1 0.0 2.1 2 0 0 2 2 1 1 RNA helicase DUF815 PF05673.8 EIW86222.1 - 0.0025 16.7 0.0 0.0053 15.7 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) KaiC PF06745.8 EIW86222.1 - 0.0028 16.8 0.0 0.9 8.6 0.0 2.3 1 1 1 2 2 2 2 KaiC AAA_2 PF07724.9 EIW86222.1 - 0.0031 17.4 0.0 0.011 15.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.1 EIW86222.1 - 0.0034 16.9 0.4 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EIW86222.1 - 0.0078 15.9 0.4 0.27 10.8 0.0 2.5 2 1 1 3 3 3 1 Archaeal ATPase ResIII PF04851.10 EIW86222.1 - 0.011 15.5 0.2 0.066 13.0 0.0 1.9 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.7 EIW86222.1 - 0.015 14.3 0.1 0.23 10.5 0.1 2.3 1 1 0 1 1 1 0 Zeta toxin AAA_19 PF13245.1 EIW86222.1 - 0.024 14.3 0.0 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Mg_chelatase PF01078.16 EIW86222.1 - 0.031 13.4 0.0 0.061 12.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EIW86222.1 - 0.046 13.7 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain NACHT PF05729.7 EIW86222.1 - 0.05 13.2 0.0 0.25 10.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain PhoH PF02562.11 EIW86222.1 - 0.05 12.8 1.9 0.079 12.1 0.1 2.1 2 1 0 2 2 2 0 PhoH-like protein Parvo_NS1 PF01057.12 EIW86222.1 - 0.056 12.3 0.0 0.098 11.5 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.21 EIW86222.1 - 0.13 11.7 0.0 0.59 9.6 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain ING PF12998.2 EIW86223.1 - 2.4e-10 40.6 7.5 1.4e-05 25.2 0.0 2.7 3 0 0 3 3 3 2 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EIW86223.1 - 1.6e-09 37.2 9.6 2.8e-09 36.5 6.6 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EIW86223.1 - 0.035 14.2 0.9 0.085 13.0 0.6 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 EIW86223.1 - 0.28 11.2 2.2 0.52 10.3 1.5 1.4 1 0 0 1 1 1 0 RING-like domain PHD_2 PF13831.1 EIW86223.1 - 1.2 8.4 4.4 0.81 9.0 1.9 1.6 1 1 0 1 1 1 0 PHD-finger Methyltransf_16 PF10294.4 EIW86224.1 - 2.6e-17 62.7 0.0 3.7e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase MutS_V PF00488.16 EIW86225.1 - 2.1e-69 233.5 0.1 3.5e-69 232.7 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EIW86225.1 - 6.6e-31 107.6 1.2 6.6e-31 107.6 0.8 2.0 2 0 0 2 2 2 1 MutS domain III MutS_II PF05188.12 EIW86225.1 - 1.6e-07 31.4 0.2 9.9e-07 28.8 0.0 2.5 2 1 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EIW86225.1 - 2.5e-06 27.5 0.0 6.8e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV DAO PF01266.19 EIW86226.1 - 2.2e-31 109.0 0.0 2.8e-30 105.4 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EIW86226.1 - 0.049 13.6 0.0 6.1 6.8 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase RNA_pol_Rpb1_1 PF04997.7 EIW86228.1 - 1.3e-116 389.5 0.0 1.8e-116 389.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EIW86228.1 - 7.7e-107 356.6 0.0 1.1e-106 356.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_6 PF04992.9 EIW86228.1 - 1.3e-68 230.4 0.2 3e-68 229.2 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_2 PF00623.15 EIW86228.1 - 2.3e-68 229.3 0.0 4.3e-68 228.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EIW86228.1 - 5.7e-52 175.6 0.0 1.2e-51 174.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EIW86228.1 - 1.7e-44 150.8 0.5 3.5e-44 149.7 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EIW86228.1 - 7e-37 125.4 0.0 1.4e-36 124.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EIW86228.1 - 0.00011 21.9 202.6 0.2 11.8 8.0 14.1 9 2 2 11 11 11 6 RNA polymerase Rpb1 C-terminal repeat VHS PF00790.14 EIW86229.1 - 2.2e-41 140.7 0.9 2e-40 137.6 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 EIW86229.1 - 2.2e-17 62.7 6.8 4.2e-17 61.7 4.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 EIW86229.1 - 0.00053 19.8 2.6 0.0012 18.7 1.8 1.5 1 0 0 1 1 1 1 FYVE-type zinc finger UIM PF02809.15 EIW86229.1 - 0.00054 19.3 8.8 0.049 13.2 1.2 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif DZR PF12773.2 EIW86229.1 - 1.9 8.3 9.3 54 3.7 6.4 2.4 1 1 0 1 1 1 0 Double zinc ribbon C1_1 PF00130.17 EIW86229.1 - 8.5 6.2 13.1 1 9.1 3.8 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Vps35 PF03635.12 EIW86230.1 - 0 1020.5 0.0 0 1020.2 0.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 BCIP PF13862.1 EIW86231.1 - 2.3e-62 209.9 0.0 3e-62 209.6 0.0 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein Pro_dh PF01619.13 EIW86232.1 - 7.4e-32 110.5 0.0 2.5e-16 59.5 0.0 2.8 3 1 0 3 3 3 2 Proline dehydrogenase DNA_methylase PF00145.12 EIW86233.1 - 1.9e-28 99.5 0.0 3.4e-28 98.7 0.0 1.4 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase HTH_16 PF12645.2 EIW86234.1 - 0.42 10.5 2.8 0.7 9.8 0.5 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain DNA_methylase PF00145.12 EIW86237.1 - 2.1e-06 27.0 0.0 2.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase TIP120 PF08623.5 EIW86241.1 - 3.1e-52 176.5 0.1 3.1e-52 176.5 0.1 2.7 3 0 0 3 3 3 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EIW86241.1 - 1.9e-20 72.9 11.1 7.6e-05 22.9 0.1 8.7 6 2 3 9 9 9 6 HEAT repeats HEAT PF02985.17 EIW86241.1 - 5.3e-20 69.6 19.0 0.0089 16.0 0.0 12.6 13 0 0 13 13 12 5 HEAT repeat HEAT_EZ PF13513.1 EIW86241.1 - 2.3e-15 56.5 23.3 0.19 12.2 0.1 11.8 12 2 3 15 15 13 5 HEAT-like repeat Cnd1 PF12717.2 EIW86241.1 - 3.2e-12 46.6 1.3 0.29 10.9 0.0 6.5 3 2 2 6 6 6 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EIW86241.1 - 6.3e-09 35.5 5.1 0.084 12.2 0.0 7.0 8 0 0 8 8 8 2 CLASP N terminal Adaptin_N PF01602.15 EIW86241.1 - 9.6e-09 34.0 6.4 0.096 10.9 0.1 5.5 3 1 1 4 4 4 3 Adaptin N terminal region Vac14_Fab1_bd PF12755.2 EIW86241.1 - 1.7e-06 28.3 1.0 8.7 6.8 0.1 7.5 7 2 1 8 8 8 1 Vacuolar 14 Fab1-binding region UME PF08064.8 EIW86241.1 - 6.9e-05 22.7 0.5 0.094 12.6 0.0 4.3 3 1 0 3 3 3 1 UME (NUC010) domain ParcG PF10274.4 EIW86241.1 - 0.00022 21.1 0.8 0.43 10.4 0.0 4.1 5 0 0 5 5 5 1 Parkin co-regulated protein DUF3385 PF11865.3 EIW86241.1 - 0.00031 20.7 1.3 0.011 15.7 0.0 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3385) MMS19_C PF12460.3 EIW86241.1 - 0.0016 17.2 24.7 0.26 9.9 0.3 6.1 5 1 1 6 6 6 3 RNAPII transcription regulator C-terminal DUF2454 PF10521.4 EIW86241.1 - 0.0071 15.3 7.5 1 8.3 0.1 5.1 4 2 1 5 5 5 1 Protein of unknown function (DUF2454) DUF2435 PF10363.4 EIW86241.1 - 0.016 15.1 3.0 0.55 10.1 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF2435) RGS-like PF09128.6 EIW86241.1 - 0.045 13.2 0.9 0.17 11.3 0.1 2.1 2 0 0 2 2 2 0 Regulator of G protein signalling-like domain V-ATPase_H_C PF11698.3 EIW86241.1 - 0.15 11.9 0.4 5.7 6.8 0.1 3.7 4 1 1 5 5 5 0 V-ATPase subunit H L51_S25_CI-B8 PF05047.11 EIW86243.1 - 3.3e-10 39.5 0.0 5.8e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Peptidase_M1 PF01433.15 EIW86245.1 - 9.7e-61 205.9 0.0 1.4e-60 205.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EIW86245.1 - 6.6e-25 87.3 0.0 2.6e-24 85.4 0.0 2.0 2 1 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EIW86245.1 - 2.3e-13 50.3 0.7 4.5e-13 49.3 0.1 1.8 2 0 0 2 2 2 1 Peptidase MA superfamily AAA_18 PF13238.1 EIW86246.1 - 2.5e-05 24.5 0.0 3.6e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EIW86246.1 - 0.011 15.6 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EIW86246.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Mg_chelatase PF01078.16 EIW86246.1 - 0.016 14.3 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EIW86246.1 - 0.065 12.9 0.0 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) YL1 PF05764.8 EIW86247.1 - 1.3e-30 106.8 20.3 1.7e-30 106.3 14.1 1.2 1 0 0 1 1 1 1 YL1 nuclear protein YL1_C PF08265.6 EIW86247.1 - 1.6e-12 46.7 0.0 2.6e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain TFIIS_C PF01096.13 EIW86249.1 - 2.8e-16 58.8 10.3 1.3e-15 56.7 1.1 3.1 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EIW86249.1 - 3.4e-06 26.6 5.2 5e-06 26.0 0.4 2.8 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit IBR PF01485.16 EIW86249.1 - 5.7e-05 22.9 4.8 0.017 14.9 0.2 2.3 2 0 0 2 2 2 2 IBR domain DZR PF12773.2 EIW86249.1 - 0.00013 21.7 7.4 0.0024 17.6 0.3 2.7 2 1 0 2 2 2 1 Double zinc ribbon Baculo_LEF5_C PF11792.3 EIW86249.1 - 0.00017 20.9 0.4 0.00017 20.9 0.3 2.6 3 0 0 3 3 2 1 Baculoviridae late expression factor 5 C-terminal domain zinc_ribbon_2 PF13240.1 EIW86249.1 - 0.002 17.5 3.3 0.002 17.5 2.3 2.6 3 0 0 3 3 3 1 zinc-ribbon domain zf-NADH-PPase PF09297.6 EIW86249.1 - 0.051 13.0 6.0 2.4 7.7 0.0 3.3 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain OrfB_Zn_ribbon PF07282.6 EIW86249.1 - 0.094 12.3 0.5 0.094 12.3 0.3 2.5 2 1 0 2 2 2 0 Putative transposase DNA-binding domain zf-C4pol PF14260.1 EIW86249.1 - 0.17 11.9 3.9 0.21 11.6 0.6 2.4 1 1 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta zf-ribbon_3 PF13248.1 EIW86249.1 - 0.18 11.0 15.9 0.22 10.7 3.8 3.5 3 1 1 4 4 4 0 zinc-ribbon domain DUF2387 PF09526.5 EIW86249.1 - 0.22 11.4 8.6 1.1 9.2 0.4 2.6 2 1 0 2 2 2 0 Probable metal-binding protein (DUF2387) Cytochrome_C554 PF13435.1 EIW86249.1 - 0.28 11.2 3.7 0.39 10.7 2.5 1.2 1 0 0 1 1 1 0 Cytochrome c554 and c-prime Lar_restr_allev PF14354.1 EIW86249.1 - 0.29 11.4 9.0 0.67 10.3 0.4 2.8 2 1 0 2 2 2 0 Restriction alleviation protein Lar DUF2296 PF10058.4 EIW86249.1 - 0.37 10.5 5.3 25 4.7 0.0 3.6 4 0 0 4 4 4 0 Predicted integral membrane metal-binding protein (DUF2296) DUF164 PF02591.10 EIW86249.1 - 0.74 9.6 5.6 2.2 8.1 0.0 3.3 4 0 0 4 4 4 0 Putative zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 EIW86249.1 - 0.82 9.5 14.3 1.1 9.0 1.0 3.3 2 2 1 3 3 3 0 Transposase zinc-ribbon domain Cys_rich_CPCC PF14206.1 EIW86249.1 - 0.99 9.0 5.1 1.2 8.7 0.0 2.4 3 0 0 3 3 3 0 Cysteine-rich CPCC UPF0547 PF10571.4 EIW86249.1 - 1.7 8.4 14.8 0.88 9.3 0.2 2.9 3 1 0 3 3 2 0 Uncharacterised protein family UPF0547 zinc-ribbons_6 PF07191.7 EIW86249.1 - 1.7 8.5 8.2 0.75 9.6 0.3 2.5 2 1 0 2 2 2 0 zinc-ribbons C1_4 PF07975.7 EIW86249.1 - 2.2 8.3 9.1 5.9 6.9 1.1 3.0 2 2 0 2 2 2 0 TFIIH C1-like domain PhnA_Zn_Ribbon PF08274.7 EIW86249.1 - 2.5 7.9 17.0 1.3 8.8 0.2 3.9 3 1 0 3 3 3 0 PhnA Zinc-Ribbon zf-FCS PF06467.9 EIW86249.1 - 2.9 7.6 6.5 15 5.2 0.2 3.2 2 1 1 3 3 3 0 MYM-type Zinc finger with FCS sequence motif RecR PF02132.10 EIW86249.1 - 5.3 6.5 6.1 1.2 8.5 1.2 2.2 2 1 0 2 2 2 0 RecR protein PHD PF00628.24 EIW86249.1 - 7.5 6.3 9.5 5.6 6.7 1.1 3.1 2 2 1 3 3 3 0 PHD-finger HypA PF01155.14 EIW86249.1 - 8.8 6.0 7.6 3.7 7.2 0.3 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family TB2_DP1_HVA22 PF03134.14 EIW86250.1 - 1.7e-25 88.5 1.9 2.6e-25 87.9 1.3 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Cyclase_polyket PF04673.7 EIW86250.1 - 0.1 12.6 0.2 0.53 10.3 0.1 2.0 2 0 0 2 2 2 0 Polyketide synthesis cyclase ABC_tran PF00005.22 EIW86252.1 - 6.3e-46 156.0 0.7 1e-21 77.6 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 EIW86252.1 - 1.6e-21 75.9 6.9 1.6e-21 75.9 4.8 2.8 3 1 0 3 3 1 1 ABC transporter AAA_21 PF13304.1 EIW86252.1 - 4.1e-18 66.3 6.6 0.00037 20.5 0.1 4.7 4 1 1 5 5 4 4 AAA domain SMC_N PF02463.14 EIW86252.1 - 3.2e-08 33.0 2.0 0.032 13.4 0.0 4.3 4 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EIW86252.1 - 5.1e-08 33.7 1.4 0.012 16.3 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.1 EIW86252.1 - 2.2e-07 30.2 0.3 0.0083 15.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EIW86252.1 - 7.2e-07 29.7 0.0 0.033 14.6 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EIW86252.1 - 7.8e-07 29.0 0.0 0.0067 16.3 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 EIW86252.1 - 3.7e-06 27.2 2.5 0.3 11.4 0.0 4.6 5 0 0 5 5 5 2 AAA domain AAA_28 PF13521.1 EIW86252.1 - 4e-06 26.8 0.1 0.06 13.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EIW86252.1 - 4.6e-06 25.9 0.0 0.03 13.5 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIW86252.1 - 3.4e-05 23.9 1.4 0.3 11.2 0.0 3.9 3 2 0 3 3 3 2 AAA domain NACHT PF05729.7 EIW86252.1 - 0.00013 21.6 0.0 0.61 9.7 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 EIW86252.1 - 0.00021 21.3 6.4 0.019 14.9 0.3 3.4 5 0 0 5 5 3 2 AAA ATPase domain MobB PF03205.9 EIW86252.1 - 0.00023 20.8 0.0 0.33 10.6 0.0 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B SbcCD_C PF13558.1 EIW86252.1 - 0.00035 20.4 4.0 0.067 13.1 0.1 3.9 3 2 0 3 3 3 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EIW86252.1 - 0.0012 18.3 0.6 0.89 8.9 0.0 3.4 3 1 0 3 3 3 1 AAA-like domain AAA_33 PF13671.1 EIW86252.1 - 0.002 17.9 0.2 0.94 9.3 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA PF00004.24 EIW86252.1 - 0.0041 17.3 0.0 4 7.6 0.0 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EIW86252.1 - 0.0044 16.9 0.0 4.6 7.1 0.0 3.2 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EIW86252.1 - 0.0049 15.6 2.8 0.25 10.0 0.1 2.6 3 0 0 3 3 3 1 ArgK protein DUF815 PF05673.8 EIW86252.1 - 0.0056 15.6 0.0 0.16 10.8 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EIW86252.1 - 0.0078 16.3 0.0 1.9 8.7 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Dynamin_N PF00350.18 EIW86252.1 - 0.011 15.5 4.4 0.2 11.4 0.1 3.5 3 1 0 3 3 3 0 Dynamin family AAA_25 PF13481.1 EIW86252.1 - 0.012 14.9 0.3 2.7 7.3 0.0 3.1 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.1 EIW86252.1 - 0.025 14.9 18.4 0.025 14.9 0.0 4.8 5 0 0 5 5 5 0 AAA domain NTPase_1 PF03266.10 EIW86252.1 - 0.037 13.7 0.0 7.2 6.2 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.9 EIW86252.1 - 0.038 13.7 0.1 4.7 6.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) DUF87 PF01935.12 EIW86252.1 - 0.053 13.3 0.1 0.053 13.3 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function DUF87 cobW PF02492.14 EIW86252.1 - 0.076 12.4 0.1 11 5.4 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EIW86252.1 - 0.12 11.8 0.0 5.1 6.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.1 EIW86252.1 - 2.1 7.3 19.4 0.22 10.5 0.2 4.8 4 2 1 6 6 6 0 AAA ATPase domain DNA_topoisoIV PF00521.15 EIW86253.1 - 2.9e-124 415.1 0.0 5e-124 414.3 0.0 1.4 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EIW86253.1 - 1.9e-35 121.5 2.0 1.9e-35 121.5 1.4 1.9 2 0 0 2 2 2 1 DNA gyrase B Toprim PF01751.17 EIW86253.1 - 1.1e-14 54.1 0.0 5e-14 52.0 0.0 2.2 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EIW86253.1 - 6.7e-09 35.4 0.0 2e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toxin_45 PF15524.1 EIW86253.1 - 0.03 14.4 0.1 0.12 12.5 0.1 2.0 1 0 0 1 1 1 0 Putative toxin 45 PAM2 PF07145.10 EIW86254.1 - 0.0037 16.6 5.3 0.014 14.8 0.2 3.5 2 1 1 3 3 3 1 Ataxin-2 C-terminal region Flavi_NS1 PF00948.16 EIW86254.1 - 1.3 7.3 2.7 2.4 6.4 1.9 1.3 1 0 0 1 1 1 0 Flavivirus non-structural Protein NS1 IncA PF04156.9 EIW86254.1 - 8.3 5.9 62.2 0.52 9.8 11.5 5.0 1 1 4 5 5 5 0 IncA protein Oxysterol_BP PF01237.13 EIW86255.1 - 5.5e-85 284.9 0.0 7.1e-85 284.5 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein DEAD PF00270.24 EIW86256.1 - 8.5e-42 142.5 0.0 2.1e-41 141.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW86256.1 - 1.3e-26 92.2 0.0 1e-25 89.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW86256.1 - 0.011 15.5 0.0 0.011 15.5 0.0 2.9 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit MIP-T3 PF10243.4 EIW86256.1 - 0.071 11.5 30.9 0.022 13.2 19.4 1.5 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 CMS1 PF14617.1 EIW86256.1 - 0.58 9.1 0.0 0.58 9.1 0.0 3.2 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit SOBP PF15279.1 EIW86256.1 - 1.8 8.8 14.6 3.3 7.9 10.1 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein SAPS PF04499.10 EIW86256.1 - 2.1 6.8 8.4 3.1 6.3 5.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DOT1 PF08123.8 EIW86257.1 - 4.3e-66 222.1 0.0 5.2e-66 221.8 0.0 1.1 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 EIW86257.1 - 2.1e-05 25.0 0.0 7.7e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW86257.1 - 0.00031 20.7 0.0 0.00051 20.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW86257.1 - 0.086 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Actin PF00022.14 EIW86258.1 - 3.4e-42 144.2 0.0 3.8e-22 78.2 0.0 2.2 2 0 0 2 2 2 2 Actin RNA_pol_Rpc4 PF05132.9 EIW86258.1 - 2.3 8.1 7.8 1.3 9.0 0.2 2.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 Ras PF00071.17 EIW86259.1 - 9.5e-65 216.9 0.0 1.1e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW86259.1 - 2e-19 70.2 0.0 2.9e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW86259.1 - 1.5e-14 53.5 0.1 2e-14 53.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIW86259.1 - 5e-06 26.0 0.0 1.3e-05 24.7 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EIW86259.1 - 1.4e-05 24.3 0.0 1.7e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EIW86259.1 - 0.00026 20.9 0.0 0.00039 20.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIW86259.1 - 0.0055 15.9 0.0 0.12 11.6 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.1 EIW86259.1 - 0.028 14.4 0.1 0.044 13.7 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain SRPRB PF09439.5 EIW86259.1 - 0.028 13.6 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.1 EIW86259.1 - 0.035 13.6 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.24 EIW86259.1 - 0.047 13.8 0.0 0.49 10.5 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIW86259.1 - 0.05 13.7 0.0 0.1 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIW86259.1 - 0.062 12.4 0.0 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NACHT PF05729.7 EIW86259.1 - 0.079 12.6 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Septin PF00735.13 EIW86259.1 - 0.096 11.6 0.0 0.18 10.8 0.0 1.5 1 0 0 1 1 1 0 Septin Dpoe2NT PF12213.3 EIW86260.1 - 0.058 13.3 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal Pectate_lyase_3 PF12708.2 EIW86262.1 - 1.7e-78 263.8 33.7 1.4e-63 215.0 6.9 3.9 3 1 1 4 4 4 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EIW86262.1 - 2.4e-06 26.8 2.9 0.032 13.6 0.1 2.8 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Alpha-L-AF_C PF06964.7 EIW86263.1 - 7.1e-31 107.3 0.3 4.6e-28 98.1 0.2 2.5 1 1 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus CBM_4_9 PF02018.12 EIW86263.1 - 0.00016 21.6 2.2 0.00027 20.9 0.4 2.2 2 0 0 2 2 2 1 Carbohydrate binding domain CBM_6 PF03422.10 EIW86263.1 - 0.0078 16.3 3.1 0.0078 16.3 2.1 2.3 2 0 0 2 2 2 1 Carbohydrate binding module (family 6) Ubie_methyltran PF01209.13 EIW86263.1 - 0.029 13.4 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Gmad2 PF10648.4 EIW86263.1 - 0.07 13.3 0.3 0.24 11.5 0.2 1.9 1 0 0 1 1 1 0 Immunoglobulin-like domain of bacterial spore germination End_beta_barrel PF12195.3 EIW86263.1 - 0.32 10.7 5.1 5.1 6.9 0.3 2.8 2 0 0 2 2 2 0 Beta barrel domain of bacteriophage endosialidase ABC_tran PF00005.22 EIW86264.1 - 9e-27 94.0 0.0 4.1e-26 91.9 0.0 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIW86264.1 - 4e-11 43.4 1.0 3.8e-09 36.9 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EIW86264.1 - 3.6e-07 29.5 0.0 0.018 14.1 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EIW86264.1 - 1e-05 24.8 0.0 0.096 11.9 0.3 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EIW86264.1 - 0.00053 20.3 0.8 0.00069 19.9 0.0 1.5 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EIW86264.1 - 0.0012 18.9 0.0 0.0085 16.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EIW86264.1 - 0.002 17.5 0.0 0.0053 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EIW86264.1 - 0.0026 17.6 0.1 0.0069 16.2 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EIW86264.1 - 0.028 15.2 0.0 0.072 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIW86264.1 - 0.036 13.2 0.0 0.074 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_19 PF13245.1 EIW86264.1 - 0.038 13.7 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 EIW86264.1 - 0.046 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.15 EIW86264.1 - 0.066 11.8 0.0 0.1 11.2 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit AAA_30 PF13604.1 EIW86264.1 - 0.1 12.1 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIW86264.1 - 0.11 11.6 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EIW86264.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.1 EIW86264.1 - 0.17 10.3 0.0 0.26 9.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Nic96 PF04097.9 EIW86265.1 - 1.5e-127 426.2 0.0 4.1e-127 424.8 0.0 1.6 1 1 0 1 1 1 1 Nup93/Nic96 DDE_1 PF03184.14 EIW86268.1 - 1.1e-07 31.2 0.0 1.3e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_3 PF13358.1 EIW86268.1 - 0.00063 19.5 0.0 0.0011 18.7 0.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease DUF3464 PF11947.3 EIW86270.1 - 0.83 9.1 5.2 1.5 8.2 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Pkinase PF00069.20 EIW86271.1 - 8.9e-06 25.0 0.0 9e-06 25.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Kdo PF06293.9 EIW86271.1 - 0.0028 16.7 0.1 0.0028 16.7 0.0 1.0 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_Tyr PF07714.12 EIW86271.1 - 0.011 14.7 0.0 0.011 14.7 0.0 1.1 1 0 0 1 1 1 0 Protein tyrosine kinase Thiolase_N PF00108.18 EIW86273.1 - 7.5e-08 31.6 0.0 9.4e-07 28.0 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EIW86273.1 - 3.3e-06 26.5 0.0 1.5e-05 24.4 0.0 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EIW86273.1 - 6.5e-06 25.8 2.2 0.0015 18.0 0.1 2.9 2 1 1 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EIW86273.1 - 7.9e-05 22.2 0.1 0.037 13.6 0.1 2.8 3 0 0 3 3 3 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FYVE PF01363.16 EIW86274.1 - 1e-17 63.7 6.2 1.8e-17 62.9 4.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.16 EIW86274.1 - 5.5 6.9 10.1 0.066 13.0 1.7 1.7 2 0 0 2 2 2 0 IBR domain PBP PF01161.15 EIW86275.1 - 1.4e-21 76.8 0.6 3.1e-21 75.7 0.4 1.5 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein YusW PF14039.1 EIW86275.1 - 0.047 13.9 0.5 0.088 13.0 0.4 1.4 1 0 0 1 1 1 0 YusW-like protein AAA_22 PF13401.1 EIW86277.1 - 0.0019 18.3 0.0 0.0019 18.3 0.0 1.2 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EIW86277.1 - 0.0038 17.6 0.0 0.0038 17.6 0.0 1.2 1 1 0 1 1 1 1 Miro-like protein SRP54 PF00448.17 EIW86277.1 - 0.0058 16.0 0.1 0.006 16.0 0.0 1.1 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain KaiC PF06745.8 EIW86277.1 - 0.013 14.6 0.0 0.013 14.6 0.0 1.1 1 0 0 1 1 1 0 KaiC T2SE PF00437.15 EIW86277.1 - 0.014 14.3 0.2 0.02 13.8 0.1 1.3 1 1 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.7 EIW86277.1 - 0.016 14.8 0.0 0.023 14.3 0.0 1.2 1 0 0 1 1 1 0 NACHT domain Zeta_toxin PF06414.7 EIW86277.1 - 0.02 14.0 0.4 0.35 9.9 0.1 2.0 1 1 1 2 2 2 0 Zeta toxin ABC_tran PF00005.22 EIW86277.1 - 0.02 15.1 0.0 0.02 15.1 0.0 1.2 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 EIW86277.1 - 0.021 14.7 0.2 0.041 13.7 0.1 1.5 1 1 1 2 2 2 0 AAA domain Glug PF07581.7 EIW86277.1 - 0.024 14.8 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 The GLUG motif AAA_19 PF13245.1 EIW86277.1 - 0.03 14.0 0.6 0.058 13.1 0.5 1.5 1 1 0 1 1 1 0 Part of AAA domain MobB PF03205.9 EIW86277.1 - 0.031 13.9 0.2 0.05 13.2 0.1 1.4 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EIW86277.1 - 0.036 13.6 0.0 0.039 13.5 0.0 1.1 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EIW86277.1 - 0.073 12.5 0.1 0.1 12.0 0.0 1.3 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 EIW86277.1 - 0.099 12.6 0.0 0.099 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EIW86277.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 EIW86277.1 - 0.12 11.8 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain DEAD PF00270.24 EIW86277.1 - 0.13 11.7 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_23 PF13476.1 EIW86277.1 - 0.14 12.4 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 AAA domain HA2 PF04408.18 EIW86278.1 - 1.7e-27 95.3 0.0 7.2e-27 93.3 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EIW86278.1 - 1.2e-23 83.1 0.0 8e-23 80.4 0.0 2.1 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EIW86278.1 - 7.3e-12 44.9 0.0 1.5e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AstB PF04996.7 EIW86278.1 - 0.076 11.8 0.1 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Succinylarginine dihydrolase US2 PF02476.10 EIW86278.1 - 0.08 13.4 0.0 5.5 7.4 0.0 2.5 2 0 0 2 2 2 0 US2 family Sel1 PF08238.7 EIW86279.1 - 3.1e-21 75.2 9.6 7.2e-07 29.6 0.0 4.0 4 0 0 4 4 4 3 Sel1 repeat TPR_16 PF13432.1 EIW86279.1 - 0.0083 16.7 1.0 0.028 15.1 0.6 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIW86279.1 - 0.19 12.4 1.9 4.6 8.1 0.2 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat LSM PF01423.17 EIW86280.1 - 1.6e-10 40.3 0.1 1.9e-10 40.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain DUF4444 PF14563.1 EIW86280.1 - 0.11 11.9 0.5 0.28 10.6 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4444) Glycos_transf_2 PF00535.21 EIW86281.1 - 6.1e-32 110.6 0.0 7.6e-32 110.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EIW86281.1 - 2.9e-13 50.1 0.0 4e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EIW86281.1 - 4.5e-09 35.7 0.0 5.7e-09 35.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Spindle_Spc25 PF08234.7 EIW86282.1 - 2.2e-20 72.4 0.0 4.5e-20 71.4 0.0 1.6 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Spc7 PF08317.6 EIW86282.1 - 0.0047 15.6 4.4 0.0063 15.2 3.1 1.2 1 0 0 1 1 1 1 Spc7 kinetochore protein DUF812 PF05667.6 EIW86282.1 - 0.0091 14.5 9.2 0.012 14.1 6.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) ERM PF00769.14 EIW86282.1 - 0.036 13.5 13.0 0.051 13.1 9.0 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF2400 PF09674.5 EIW86282.1 - 0.083 12.5 2.1 0.14 11.8 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) DUF4200 PF13863.1 EIW86282.1 - 0.11 12.4 15.2 0.11 12.4 8.9 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) V_ATPase_I PF01496.14 EIW86282.1 - 0.12 10.2 4.7 0.15 9.9 3.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mnd1 PF03962.10 EIW86282.1 - 0.18 11.4 8.8 0.28 10.8 6.1 1.4 1 0 0 1 1 1 0 Mnd1 family DUF2693 PF10902.3 EIW86282.1 - 0.46 10.4 2.4 0.96 9.3 0.8 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2693) IncA PF04156.9 EIW86282.1 - 1 8.9 9.1 1.6 8.3 6.3 1.3 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EIW86282.1 - 2 7.4 9.2 2.8 6.9 6.4 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF724 PF05266.9 EIW86282.1 - 2.5 7.6 8.7 2.8 7.5 5.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Pkinase PF00069.20 EIW86283.1 - 6.4e-58 195.9 0.0 1.8e-57 194.4 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW86283.1 - 1.9e-28 99.2 0.1 1e-20 73.8 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIW86283.1 - 4.1e-05 22.6 0.2 0.0003 19.8 0.0 2.3 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EIW86283.1 - 0.0018 18.0 0.3 0.08 12.6 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EIW86283.1 - 0.044 12.8 0.0 0.085 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PRP3 PF08572.5 EIW86284.1 - 8e-64 215.0 7.0 1.8e-63 213.9 4.8 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EIW86284.1 - 2.5e-32 111.2 0.0 9.9e-32 109.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1115) Ribosomal_L16 PF00252.13 EIW86285.1 - 3e-35 120.8 0.3 3.8e-35 120.5 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Alpha-L-AF_C PF06964.7 EIW86286.1 - 4.4e-42 143.8 3.0 4.4e-42 143.8 2.0 1.9 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase C-terminus CBM_6 PF03422.10 EIW86286.1 - 3.5 7.8 12.7 0.042 14.0 2.2 2.7 4 0 0 4 4 4 0 Carbohydrate binding module (family 6) Sporozoite_P67 PF05642.6 EIW86288.1 - 0.058 11.2 2.5 0.065 11.1 1.7 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.1 EIW86288.1 - 0.088 12.4 1.7 0.11 12.2 1.2 1.1 1 0 0 1 1 1 0 FAM176 family Hus1 PF04005.7 EIW86288.1 - 0.098 11.5 0.9 0.12 11.3 0.7 1.2 1 0 0 1 1 1 0 Hus1-like protein DUF4526 PF15029.1 EIW86288.1 - 0.15 11.6 0.4 0.18 11.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4526) CDC45 PF02724.9 EIW86288.1 - 0.33 8.9 2.6 0.35 8.8 1.8 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4637 PF15470.1 EIW86288.1 - 0.48 10.0 5.5 0.61 9.6 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) TRAP_alpha PF03896.11 EIW86288.1 - 1.2 8.0 5.9 1.3 7.9 4.1 1.0 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Sigma70_ner PF04546.8 EIW86288.1 - 5.2 6.6 10.0 6.2 6.3 6.9 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region Ribosomal_S27 PF01599.14 EIW86291.1 - 0.074 12.8 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S27a Bromodomain PF00439.20 EIW86293.1 - 0.017 15.0 0.0 0.14 12.1 0.0 2.0 1 1 0 1 1 1 0 Bromodomain MVL PF12151.3 EIW86293.1 - 0.098 12.3 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Mannan-binding protein FbpA PF05833.6 EIW86293.1 - 0.11 11.0 0.0 0.15 10.5 0.0 1.3 1 1 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) UBN2 PF14223.1 EIW86295.1 - 0.00034 20.3 0.0 0.00074 19.3 0.0 1.6 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type UBN2_2 PF14227.1 EIW86295.1 - 0.0014 18.1 0.0 0.0031 17.0 0.0 1.6 1 1 0 1 1 1 1 gag-polypeptide of LTR copia-type HABP4_PAI-RBP1 PF04774.10 EIW86297.1 - 0.76 10.3 4.7 0.33 11.4 1.3 2.0 2 1 0 2 2 2 0 Hyaluronan / mRNA binding family DUF2562 PF10814.3 EIW86298.1 - 0.19 11.7 2.2 0.28 11.1 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) DivIVA PF05103.8 EIW86298.1 - 0.3 11.1 3.5 0.63 10.0 2.4 1.7 1 0 0 1 1 1 0 DivIVA protein Transposase_21 PF02992.9 EIW86301.1 - 9.2e-06 24.9 0.0 1.2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 DDE_1 PF03184.14 EIW86302.1 - 8.7e-20 70.7 0.6 2.2e-18 66.1 0.1 2.7 2 1 0 2 2 2 1 DDE superfamily endonuclease Alpha_TIF PF02232.10 EIW86302.1 - 0.056 12.2 0.0 0.088 11.6 0.0 1.3 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) DUF3138 PF11336.3 EIW86303.1 - 0.016 13.3 0.1 0.024 12.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Antimicrobial19 PF08225.6 EIW86303.1 - 0.026 13.9 0.8 0.026 13.9 0.6 1.8 2 0 0 2 2 2 0 Pseudin antimicrobial peptide Helicase_C PF00271.26 EIW86304.1 - 0.002 17.9 0.1 0.0036 17.1 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2194 PF09960.4 EIW86304.1 - 0.095 10.7 0.0 0.14 10.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2194) Fijivirus_P9-2 PF06837.6 EIW86306.1 - 0.11 11.6 4.1 0.17 10.9 2.8 1.3 1 0 0 1 1 1 0 Fijivirus P9-2 protein DUF4158 PF13700.1 EIW86307.1 - 0.016 14.6 0.4 0.028 13.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) DUF1619 PF07773.6 EIW86308.1 - 0.058 13.2 0.5 0.1 12.4 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1619) PLU-1 PF08429.6 EIW86311.1 - 0.00071 18.5 0.7 0.00085 18.3 0.5 1.0 1 0 0 1 1 1 1 PLU-1-like protein PIN PF01850.16 EIW86311.1 - 0.045 14.0 0.5 0.068 13.4 0.3 1.4 1 1 0 1 1 1 0 PIN domain DUF904 PF06005.7 EIW86312.1 - 0.023 14.9 0.1 0.035 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Dimer_Tnp_hAT PF05699.9 EIW86314.1 - 0.0057 16.2 0.2 0.0067 16.0 0.2 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Ku PF02735.11 EIW86315.1 - 2.9e-26 92.1 0.1 9.7e-26 90.4 0.1 2.0 1 1 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.6 EIW86315.1 - 4.6e-15 55.5 0.0 9.4e-15 54.5 0.0 1.6 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.10 EIW86315.1 - 1.7e-12 47.2 0.1 6.5e-12 45.3 0.0 2.0 2 1 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain VWA_2 PF13519.1 EIW86315.1 - 5e-07 29.9 0.0 9.7e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EIW86315.1 - 0.0049 16.6 0.0 0.0098 15.6 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain SNF2_N PF00176.18 EIW86316.1 - 1.2e-82 277.1 0.3 2.2e-82 276.2 0.2 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EIW86316.1 - 7.8e-25 86.6 0.7 2.5e-24 85.0 0.1 2.1 2 0 0 2 2 2 1 Bromodomain Helicase_C PF00271.26 EIW86316.1 - 6.6e-17 61.1 0.0 2e-15 56.3 0.0 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SnAC PF14619.1 EIW86316.1 - 2.2e-14 53.3 1.0 2.2e-14 53.3 0.7 3.3 3 1 1 4 4 4 1 Snf2-ATP coupling, chromatin remodelling complex QLQ PF08880.6 EIW86316.1 - 3.3e-14 52.0 0.2 1.3e-13 50.1 0.2 2.0 1 0 0 1 1 1 1 QLQ HSA PF07529.8 EIW86316.1 - 4.1e-12 45.7 4.2 4.1e-12 45.7 2.9 2.1 2 0 0 2 2 2 1 HSA ResIII PF04851.10 EIW86316.1 - 0.001 18.9 0.6 0.0062 16.3 0.0 2.5 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit Chorismate_synt PF01264.16 EIW86318.1 - 3.5e-131 436.7 0.0 5e-131 436.2 0.0 1.2 1 0 0 1 1 1 1 Chorismate synthase CLP_protease PF00574.18 EIW86321.1 - 1.5e-74 249.6 0.0 1.8e-74 249.3 0.0 1.0 1 0 0 1 1 1 1 Clp protease Brr6_like_C_C PF10104.4 EIW86322.1 - 1.1e-40 138.2 0.3 1.4e-40 137.8 0.2 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain SUR7 PF06687.7 EIW86322.1 - 0.08 12.4 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 SUR7/PalI family 4F5 PF04419.9 EIW86323.1 - 1e-08 35.7 11.7 1e-08 35.7 8.1 2.1 2 0 0 2 2 2 1 4F5 protein family DUF2040 PF09745.4 EIW86323.1 - 0.0045 16.8 9.2 0.005 16.6 6.4 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 55 (DUF2040) Pinin_SDK_memA PF04696.8 EIW86323.1 - 0.61 9.6 8.6 0.73 9.4 6.0 1.1 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region U79_P34 PF03064.11 EIW86323.1 - 9.8 5.6 12.2 11 5.4 8.5 1.1 1 0 0 1 1 1 0 HSV U79 / HCMV P34 TPR_1 PF00515.23 EIW86324.1 - 2.5e-56 185.1 26.9 7.5e-08 31.6 0.0 11.2 11 1 0 11 11 11 9 Tetratricopeptide repeat TPR_2 PF07719.12 EIW86324.1 - 2.7e-52 170.4 20.8 2.7e-06 26.8 0.3 10.8 11 0 0 11 11 11 9 Tetratricopeptide repeat TPR_11 PF13414.1 EIW86324.1 - 1.8e-49 165.2 18.6 2.5e-10 39.8 0.6 7.0 2 2 4 8 8 8 7 TPR repeat TPR_8 PF13181.1 EIW86324.1 - 2.9e-41 136.1 17.0 0.00045 19.8 1.8 10.3 8 1 2 10 10 10 9 Tetratricopeptide repeat TPR_12 PF13424.1 EIW86324.1 - 1.8e-34 117.4 27.5 5.6e-08 32.6 0.1 7.5 1 1 8 9 9 9 8 Tetratricopeptide repeat TPR_14 PF13428.1 EIW86324.1 - 7.4e-34 113.1 9.1 0.0002 21.7 0.0 10.1 4 2 6 10 10 10 9 Tetratricopeptide repeat TPR_16 PF13432.1 EIW86324.1 - 5.2e-33 112.9 16.7 4e-06 27.3 0.2 7.2 4 2 4 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.1 EIW86324.1 - 1.2e-31 106.2 11.1 0.0001 22.2 0.3 10.5 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_7 PF13176.1 EIW86324.1 - 2.8e-29 98.5 12.7 0.0093 15.6 0.2 9.7 9 1 1 10 10 10 8 Tetratricopeptide repeat TPR_6 PF13174.1 EIW86324.1 - 2.6e-28 96.5 12.2 0.0018 18.5 0.0 10.2 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 EIW86324.1 - 6e-26 90.5 14.6 9.7e-07 29.0 0.2 7.0 6 2 2 8 8 8 6 Tetratricopeptide repeat Apc3 PF12895.2 EIW86324.1 - 2e-15 56.6 12.5 1.9e-05 24.6 0.7 5.2 5 0 0 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EIW86324.1 - 3.4e-13 49.2 12.4 0.031 14.1 0.1 6.4 1 1 8 9 9 9 8 Tetratricopeptide repeat TPR_15 PF13429.1 EIW86324.1 - 1.5e-10 40.6 6.2 0.00037 19.6 1.3 5.3 1 1 3 5 5 5 2 Tetratricopeptide repeat TPR_21 PF09976.4 EIW86324.1 - 9e-08 32.1 8.3 0.0031 17.4 0.2 4.1 4 1 0 4 4 4 2 Tetratricopeptide repeat SNAP PF14938.1 EIW86324.1 - 3e-06 26.5 10.3 0.012 14.8 0.4 5.2 1 1 2 4 4 4 2 Soluble NSF attachment protein, SNAP ChAPs PF09295.5 EIW86324.1 - 7.5e-06 24.9 0.5 0.12 11.1 0.0 2.6 2 1 1 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.1 EIW86324.1 - 1.9e-05 24.6 2.9 0.0026 17.8 0.1 4.4 4 1 1 5 5 5 1 Tetratricopeptide repeat DUF2225 PF09986.4 EIW86324.1 - 0.0012 18.4 1.6 0.6 9.5 0.0 3.9 1 1 2 4 4 4 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_3 PF07720.7 EIW86324.1 - 0.0049 16.6 21.2 1.3 8.8 0.7 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EIW86324.1 - 0.069 13.0 1.0 33 4.4 0.0 4.2 4 1 1 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.15 EIW86324.1 - 0.074 13.0 0.1 31 4.8 0.0 4.6 6 0 0 6 6 5 0 PPR repeat MIT PF04212.13 EIW86324.1 - 2.9 7.8 20.5 7.5 6.5 1.1 5.9 5 1 1 6 6 6 0 MIT (microtubule interacting and transport) domain Sel1 PF08238.7 EIW86324.1 - 3.5 8.3 19.0 41 5.0 0.0 5.4 5 0 0 5 5 4 0 Sel1 repeat TPR_10 PF13374.1 EIW86324.1 - 3.8 7.5 0.0 3.8 7.5 0.0 6.9 9 0 0 9 9 6 0 Tetratricopeptide repeat Erf4 PF10256.4 EIW86325.1 - 1.5e-06 28.0 0.0 1.7e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family UPF0052 PF01933.13 EIW86326.1 - 1.8e-45 155.5 0.0 2.5e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 Apc3 PF12895.2 EIW86327.1 - 0.012 15.7 1.4 0.78 9.9 0.1 2.9 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EIW86327.1 - 0.024 14.5 1.1 2.3 8.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat ArsA_ATPase PF02374.10 EIW86328.1 - 1.1e-103 346.4 0.9 1.3e-103 346.2 0.6 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EIW86328.1 - 5.8e-09 35.6 0.0 1.1e-08 34.7 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EIW86328.1 - 2.1e-07 30.9 0.0 4.8e-07 29.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 EIW86328.1 - 0.0055 16.1 0.3 0.11 11.9 0.0 2.5 2 1 1 3 3 3 1 SRP54-type protein, GTPase domain Elf1 PF05129.8 EIW86328.1 - 0.091 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like UQ_con PF00179.21 EIW86329.1 - 4e-27 94.3 0.0 4.7e-27 94.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EIW86329.1 - 0.00014 21.6 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EIW86329.1 - 0.026 14.1 0.0 0.036 13.7 0.0 1.2 1 0 0 1 1 1 0 UEV domain Porphobil_deam PF01379.15 EIW86330.1 - 4.7e-74 247.9 0.0 6e-74 247.5 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EIW86330.1 - 1.8e-17 63.2 0.1 4.5e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Ribosomal_L18p PF00861.17 EIW86330.1 - 0.0058 16.8 0.4 0.013 15.7 0.3 1.5 1 0 0 1 1 1 1 Ribosomal L18p/L5e family Cu-oxidase_3 PF07732.10 EIW86331.1 - 5.2e-47 158.4 6.3 9.5e-45 151.1 2.3 3.7 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EIW86331.1 - 1.9e-38 131.1 6.1 3.9e-35 120.3 0.1 3.2 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EIW86331.1 - 8.1e-29 100.5 1.1 1.2e-27 96.7 0.0 2.9 3 0 0 3 3 3 1 Multicopper oxidase Phosphoesterase PF04185.9 EIW86332.1 - 2.6e-19 69.6 3.3 2.8e-19 69.5 2.3 1.1 1 0 0 1 1 1 1 Phosphoesterase family ELH PF02323.10 EIW86332.1 - 0.045 12.8 0.0 0.063 12.4 0.0 1.2 1 0 0 1 1 1 0 Egg-laying hormone precursor DUF1020 PF06255.8 EIW86332.1 - 0.2 10.8 2.5 0.4 9.8 1.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1020) Glyco_trans_1_4 PF13692.1 EIW86333.1 - 2.7e-20 72.8 0.0 5.2e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EIW86333.1 - 5.7e-07 29.8 0.5 2.3e-06 27.8 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase 4-like domain Glycos_transf_1 PF00534.15 EIW86333.1 - 1.2e-06 28.0 0.0 2.8e-06 26.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EIW86333.1 - 1.2e-05 25.4 0.1 3.6e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Nfu_N PF08712.6 EIW86334.1 - 2.3e-29 100.8 0.0 6.1e-29 99.4 0.0 1.7 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EIW86334.1 - 1.3e-22 79.3 0.1 2.2e-22 78.5 0.1 1.4 1 0 0 1 1 1 1 NifU-like domain YojJ PF10372.4 EIW86334.1 - 0.12 12.2 0.2 0.25 11.2 0.2 1.4 1 0 0 1 1 1 0 Bacterial membrane-spanning protein N-terminus NmrA PF05368.8 EIW86335.1 - 1.1e-16 60.8 0.0 1.7e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIW86335.1 - 6.7e-12 45.7 0.0 2.8e-11 43.7 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW86335.1 - 7.6e-05 22.2 0.0 0.00084 18.8 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family CPSase_L_chain PF00289.17 EIW86335.1 - 0.0054 16.8 0.1 0.016 15.3 0.0 1.8 1 1 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain adh_short_C2 PF13561.1 EIW86335.1 - 0.011 15.5 0.0 0.033 13.9 0.0 1.8 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EIW86335.1 - 0.028 14.3 0.1 0.055 13.3 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase RmlD_sub_bind PF04321.12 EIW86335.1 - 0.048 12.5 0.0 0.076 11.8 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DUF4350 PF14258.1 EIW86335.1 - 0.048 13.8 0.1 0.36 11.0 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4350) Pyr_redox PF00070.22 EIW86335.1 - 0.057 13.8 0.2 0.29 11.5 0.1 2.2 2 1 1 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW86335.1 - 0.11 12.6 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_3 PF03447.11 EIW86335.1 - 0.16 12.3 0.4 0.66 10.3 0.3 1.8 1 1 1 2 2 2 0 Homoserine dehydrogenase, NAD binding domain ACT_7 PF13840.1 EIW86335.1 - 0.63 9.6 3.4 23 4.6 0.1 3.0 3 1 1 4 4 4 0 ACT domain ADH_zinc_N PF00107.21 EIW86336.1 - 7e-14 51.4 0.0 1.2e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW86336.1 - 1.3e-09 37.8 0.0 2.1e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW86337.1 - 1.4e-13 50.5 0.1 2.5e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW86337.1 - 1.1e-10 41.2 0.0 1.8e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Y_phosphatase PF00102.22 EIW86338.1 - 3.1e-47 160.8 0.0 1e-38 132.9 0.0 3.8 2 1 0 2 2 2 2 Protein-tyrosine phosphatase Rhodanese PF00581.15 EIW86338.1 - 0.00013 22.2 0.0 0.00033 20.9 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 EIW86338.1 - 0.15 12.3 0.2 0.36 11.0 0.1 1.6 1 1 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 EIW86338.1 - 0.2 11.2 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Copper-fist PF00649.13 EIW86339.1 - 3.2e-21 74.2 0.5 3.2e-21 74.2 0.4 2.8 3 0 0 3 3 3 1 Copper fist DNA binding domain BAR PF03114.13 EIW86340.1 - 1.3e-42 145.9 1.1 1.8e-42 145.4 0.8 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EIW86340.1 - 4e-17 61.3 0.2 8.5e-17 60.2 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIW86340.1 - 4.4e-15 54.9 0.1 8e-15 54.1 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EIW86340.1 - 7.4e-11 41.3 0.0 1.3e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Vps5 PF09325.5 EIW86340.1 - 0.00082 18.7 1.4 0.0037 16.5 0.9 2.0 1 1 0 1 1 1 1 Vps5 C terminal like SBDS_C PF09377.5 EIW86341.1 - 4.1e-39 133.1 0.1 4.1e-39 133.1 0.1 1.8 2 1 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.13 EIW86341.1 - 8.5e-35 118.4 3.2 1.3e-34 117.8 2.2 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein XkdN PF08890.6 EIW86341.1 - 0.0022 17.7 0.4 0.0095 15.6 0.3 2.1 1 1 0 1 1 1 1 Phage XkdN-like protein Myc_N PF01056.13 EIW86341.1 - 0.03 13.4 0.0 0.04 13.0 0.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF3095 PF11294.3 EIW86341.1 - 0.039 12.9 0.1 0.057 12.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3095) Fe-S_biosyn PF01521.15 EIW86342.1 - 6.5e-20 71.1 0.0 7.8e-20 70.8 0.0 1.0 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis SPRY PF00622.23 EIW86343.1 - 7.8e-24 84.1 0.2 1.4e-23 83.3 0.1 1.4 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.4 EIW86343.1 - 2.1e-19 69.6 0.0 3.3e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EIW86343.1 - 0.00035 20.2 0.3 0.0011 18.6 0.1 1.9 2 0 0 2 2 2 1 LisH UMP1 PF05348.6 EIW86344.1 - 1.9e-19 69.8 0.3 2.2e-19 69.6 0.2 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 RdRP PF05183.7 EIW86345.1 - 9.5e-144 480.2 0.0 1.3e-143 479.7 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RdRP PF05183.7 EIW86346.1 - 2.1e-142 475.7 0.0 3.1e-142 475.2 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Prp19_bind PF06991.6 EIW86347.1 - 1.6e-64 217.8 28.8 1.6e-64 217.8 20.0 3.0 1 1 1 3 3 3 1 Splicing factor, Prp19-binding domain Glyco_hydro_72 PF03198.9 EIW86348.1 - 5.8e-93 311.3 0.4 2.3e-92 309.3 0.1 1.8 2 0 0 2 2 2 1 Glucanosyltransferase X8 PF07983.8 EIW86348.1 - 7.1e-20 71.2 6.0 2.2e-19 69.7 4.1 1.9 1 0 0 1 1 1 1 X8 domain Cellulase PF00150.13 EIW86348.1 - 0.002 17.3 0.0 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ribosomal_S14 PF00253.16 EIW86349.1 - 3.3e-17 61.6 3.7 3.5e-17 61.5 2.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Toxin_17 PF08086.6 EIW86349.1 - 0.99 9.5 3.7 0.69 10.0 0.2 2.0 1 1 1 2 2 2 0 Ergtoxin family PUF PF00806.14 EIW86350.1 - 1.2e-54 178.8 15.7 2.1e-08 33.1 0.1 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DUF260 PF03195.9 EIW86350.1 - 0.014 15.7 0.1 0.18 12.0 0.0 2.8 3 2 2 5 5 5 0 Protein of unknown function DUF260 Atg14 PF10186.4 EIW86351.1 - 4.6e-13 48.7 0.0 7.4e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Cullin PF00888.17 EIW86352.1 - 4.3e-06 25.5 0.0 5e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Cullin family RRM_1 PF00076.17 EIW86353.1 - 1.7e-14 53.2 0.1 2.4e-14 52.7 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW86353.1 - 5.1e-11 42.3 0.0 7.7e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 EIW86353.1 - 1e-08 34.6 3.3 1e-08 34.6 2.3 1.8 2 0 0 2 2 2 1 Zinc knuckle RRM_5 PF13893.1 EIW86353.1 - 2.1e-08 33.8 0.1 3.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.1 EIW86353.1 - 0.00011 21.8 0.0 0.00037 20.1 0.0 1.8 2 0 0 2 2 2 1 Zinc knuckle RNA_bind PF08675.6 EIW86353.1 - 0.001 19.0 0.0 0.0016 18.3 0.0 1.2 1 0 0 1 1 1 1 RNA binding domain zf-CCHC_4 PF14392.1 EIW86353.1 - 0.062 12.9 0.4 0.13 11.9 0.2 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 EIW86353.1 - 0.079 12.4 2.6 0.19 11.2 1.8 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RRM_3 PF08777.6 EIW86353.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif Laminin_G_1 PF00054.18 EIW86353.1 - 0.2 11.6 0.1 1.4 8.9 0.0 2.0 1 1 1 2 2 2 0 Laminin G domain PARP PF00644.15 EIW86354.1 - 1.8e-59 200.6 0.0 3.5e-59 199.7 0.0 1.5 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EIW86354.1 - 1.3e-34 118.7 0.0 1.9e-34 118.1 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 EIW86354.1 - 5.8e-22 77.4 0.0 1.4e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 WGR domain HMG_box PF00505.14 EIW86355.1 - 1.1e-06 28.7 0.0 2.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box DHO_dh PF01180.16 EIW86356.1 - 5.2e-08 32.1 0.0 1.8e-05 23.9 0.0 2.4 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase TRAPP PF04051.11 EIW86357.1 - 2.3e-39 134.3 0.0 2.8e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component WD40 PF00400.27 EIW86359.1 - 5.7e-42 140.1 0.3 3.3e-10 39.4 0.0 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EIW86359.1 - 1.4e-08 33.4 0.7 0.0048 15.1 0.0 3.5 3 1 1 4 4 4 3 Nucleoporin Nup120/160 DUF1024 PF06260.7 EIW86359.1 - 0.088 12.9 0.3 0.21 11.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1024) PQQ_3 PF13570.1 EIW86359.1 - 0.3 11.4 2.0 1.4e+02 2.9 0.1 4.9 4 2 0 4 4 4 0 PQQ-like domain BC10 PF06726.7 EIW86360.1 - 1.3e-10 41.0 12.7 2.1e-10 40.4 8.8 1.3 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 Tail_P2_I PF09684.5 EIW86360.1 - 0.094 12.2 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Phage tail protein (Tail_P2_I) CS PF04969.11 EIW86361.1 - 2e-09 37.8 0.0 3.4e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 CS domain Fork_head_N PF08430.7 EIW86361.1 - 3.9 7.8 17.2 6.3 7.2 11.9 1.3 1 0 0 1 1 1 0 Forkhead N-terminal region Sporozoite_P67 PF05642.6 EIW86361.1 - 7.8 4.2 14.2 11 3.7 9.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen p450 PF00067.17 EIW86362.1 - 2.3e-53 181.3 0.0 3e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 tRNA-synt_1e PF01406.14 EIW86363.1 - 0.0044 16.1 0.6 0.0044 16.1 0.4 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Apolipoprotein PF01442.13 EIW86363.1 - 0.033 13.6 0.6 0.041 13.3 0.4 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 EIW86363.1 - 0.044 14.1 2.0 0.044 14.1 1.4 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) LEA_1 PF03760.10 EIW86363.1 - 0.051 13.7 13.3 0.072 13.2 9.2 1.2 1 0 0 1 1 1 0 Late embryogenesis abundant (LEA) group 1 DDHD PF02862.12 EIW86363.1 - 0.13 12.0 2.2 0.13 12.0 1.5 1.1 1 0 0 1 1 1 0 DDHD domain PEP-utilisers_N PF05524.8 EIW86363.1 - 0.19 11.5 1.9 2.7 7.8 0.0 2.1 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal Phasin PF05597.6 EIW86363.1 - 0.2 11.4 8.1 0.17 11.6 3.8 1.9 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) BPL_LplA_LipB PF03099.14 EIW86364.1 - 1.9e-08 34.3 0.0 3.2e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DUF1059 PF06348.6 EIW86364.1 - 0.16 11.8 0.0 0.4 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) ATP11 PF06644.6 EIW86365.1 - 9e-65 218.8 0.0 1.1e-64 218.4 0.0 1.0 1 0 0 1 1 1 1 ATP11 protein RHH_4 PF13467.1 EIW86365.1 - 0.073 12.9 0.2 0.15 11.9 0.2 1.4 1 0 0 1 1 1 0 Ribbon-helix-helix domain RHH_1 PF01402.16 EIW86365.1 - 0.12 12.2 0.3 0.6 10.0 0.3 2.0 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Ammonium_transp PF00909.16 EIW86366.1 - 6.2e-114 380.5 22.3 7.2e-114 380.3 15.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Asp-Al_Ex PF06826.7 EIW86366.1 - 0.38 10.2 9.3 0.022 14.2 1.1 2.7 2 1 1 3 3 3 0 Predicted Permease Membrane Region Prenylcys_lyase PF07156.9 EIW86367.1 - 7.6e-43 146.8 0.0 6.3e-24 84.5 0.0 2.1 2 0 0 2 2 2 2 Prenylcysteine lyase NAD_binding_8 PF13450.1 EIW86367.1 - 5.7e-09 35.8 0.0 1.2e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EIW86367.1 - 2.5e-06 26.8 0.0 2.4e-05 23.5 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EIW86367.1 - 0.00012 22.2 0.0 0.13 12.3 0.0 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EIW86367.1 - 0.00049 19.1 0.1 0.22 10.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EIW86367.1 - 0.0006 19.6 0.0 0.0023 17.7 0.0 2.0 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EIW86367.1 - 0.078 12.8 0.0 0.41 10.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Orbi_VP7 PF00897.12 EIW86367.1 - 0.11 11.3 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Orbivirus inner capsid protein VP7 60KD_IMP PF02096.15 EIW86368.1 - 4.9 6.7 10.2 0.2 11.3 0.5 2.2 1 1 1 2 2 2 0 60Kd inner membrane protein DUF4064 PF13273.1 EIW86368.1 - 9.4 6.4 25.4 2 8.5 3.3 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) DUF3397 PF11877.3 EIW86368.1 - 9.7 6.2 16.0 0.25 11.3 0.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3397) Las1 PF04031.8 EIW86369.1 - 2e-40 137.9 0.0 3.8e-40 137.0 0.0 1.5 1 0 0 1 1 1 1 Las1-like DUF500 PF04366.7 EIW86370.1 - 5.4e-37 126.0 2.2 8e-37 125.4 1.5 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EIW86370.1 - 5.9e-16 57.5 0.0 1.2e-15 56.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EIW86370.1 - 3.4e-15 55.3 0.0 7e-14 51.1 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EIW86370.1 - 2e-12 46.4 0.1 3.4e-11 42.4 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain RhoGAP PF00620.22 EIW86372.1 - 1.5e-41 141.5 0.0 4e-41 140.1 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EIW86372.1 - 2.8e-07 30.6 0.7 8e-07 29.1 0.5 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain ABC_membrane PF00664.18 EIW86373.1 - 2.1e-47 161.8 25.3 6.6e-25 88.0 1.2 3.5 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EIW86373.1 - 1.1e-44 152.0 0.0 2.9e-26 92.3 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EIW86373.1 - 3.6e-12 45.9 5.5 0.0012 18.1 0.2 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EIW86373.1 - 3.7e-10 40.2 0.1 0.019 14.9 0.1 4.3 2 2 1 3 3 3 3 AAA domain AAA_25 PF13481.1 EIW86373.1 - 1.1e-07 31.4 0.0 0.016 14.5 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_23 PF13476.1 EIW86373.1 - 2.8e-07 31.0 0.1 0.00016 22.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EIW86373.1 - 4.6e-06 26.0 0.1 0.042 13.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EIW86373.1 - 1.3e-05 25.2 2.7 0.044 13.7 0.2 2.5 2 0 0 2 2 2 2 AAA ATPase domain MobB PF03205.9 EIW86373.1 - 0.00012 21.7 0.2 0.68 9.6 0.0 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EIW86373.1 - 0.00013 20.9 0.0 0.023 13.5 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_17 PF13207.1 EIW86373.1 - 0.00019 22.2 0.0 0.86 10.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain FtsK_SpoIIIE PF01580.13 EIW86373.1 - 0.00027 20.4 0.1 0.81 9.1 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_22 PF13401.1 EIW86373.1 - 0.00029 21.0 1.4 0.34 11.0 0.0 3.3 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 EIW86373.1 - 0.00053 20.4 0.0 1.1 9.7 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 EIW86373.1 - 0.00056 19.1 0.1 0.56 9.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Adeno_IVa2 PF02456.10 EIW86373.1 - 0.00057 18.6 0.1 0.0025 16.5 0.0 1.9 2 0 0 2 2 2 1 Adenovirus IVa2 protein MMR_HSR1 PF01926.18 EIW86373.1 - 0.00071 19.5 0.1 0.62 10.0 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF87 PF01935.12 EIW86373.1 - 0.001 18.9 1.4 0.081 12.7 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_10 PF12846.2 EIW86373.1 - 0.0015 18.0 2.8 2 7.7 0.1 3.2 3 0 0 3 3 3 2 AAA-like domain AAA_18 PF13238.1 EIW86373.1 - 0.0016 18.7 0.0 2.7 8.3 0.0 3.2 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 EIW86373.1 - 0.0033 16.9 0.1 1.2 8.5 0.0 2.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Arch_ATPase PF01637.13 EIW86373.1 - 0.0045 16.7 0.2 0.095 12.3 0.0 2.6 2 1 0 2 2 2 1 Archaeal ATPase Pox_A32 PF04665.7 EIW86373.1 - 0.0096 15.2 0.3 3.3 6.9 0.0 2.4 2 0 0 2 2 2 1 Poxvirus A32 protein Zeta_toxin PF06414.7 EIW86373.1 - 0.013 14.5 0.0 0.44 9.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin SbcCD_C PF13558.1 EIW86373.1 - 0.015 15.2 0.7 2 8.3 0.2 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ResIII PF04851.10 EIW86373.1 - 0.016 15.0 0.0 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit IstB_IS21 PF01695.12 EIW86373.1 - 0.02 14.3 0.0 8.4 5.7 0.0 2.7 3 0 0 3 3 2 0 IstB-like ATP binding protein AAA_33 PF13671.1 EIW86373.1 - 0.029 14.2 0.1 0.94 9.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.9 EIW86373.1 - 0.035 13.8 0.7 7.6 6.2 0.0 3.2 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) Dynamin_N PF00350.18 EIW86373.1 - 0.042 13.6 0.5 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 Dynamin family NACHT PF05729.7 EIW86373.1 - 0.057 13.0 0.4 2.2 7.9 0.1 2.6 2 0 0 2 2 2 0 NACHT domain cobW PF02492.14 EIW86373.1 - 0.19 11.1 1.7 1.3 8.4 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain LRV_FeS PF05484.6 EIW86374.1 - 0.038 13.5 0.1 0.092 12.3 0.0 1.6 1 0 0 1 1 1 0 LRV protein FeS4 cluster Dynein_heavy PF03028.10 EIW86375.1 - 6.6e-178 593.0 0.9 1.6e-177 591.7 0.0 2.0 2 0 0 2 2 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N2 PF08393.8 EIW86375.1 - 8.8e-133 442.7 9.0 8.8e-133 442.7 6.3 3.0 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 EIW86375.1 - 5.7e-77 258.3 0.0 1.8e-76 256.7 0.0 1.9 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 EIW86375.1 - 3.9e-45 153.4 0.2 1.7e-44 151.3 0.1 2.3 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 EIW86375.1 - 4.5e-45 153.7 0.1 8.4e-44 149.5 0.1 2.5 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 EIW86375.1 - 5.8e-40 137.0 5.9 1e-39 136.2 4.1 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EIW86375.1 - 1.2e-29 102.8 0.0 2.2e-12 46.8 0.0 6.6 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EIW86375.1 - 1.9e-19 69.7 0.0 7e-19 67.9 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region D3 AAA PF00004.24 EIW86375.1 - 4.4e-13 49.5 0.2 0.00076 19.6 0.0 4.9 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EIW86375.1 - 9.9e-13 48.3 0.0 0.021 14.9 0.0 5.5 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.1 EIW86375.1 - 7.1e-12 45.4 0.3 0.11 12.3 0.0 6.0 5 1 0 5 5 5 3 AAA domain AAA_17 PF13207.1 EIW86375.1 - 3.8e-08 34.1 0.0 0.13 13.0 0.0 5.8 4 0 0 4 4 4 1 AAA domain AAA_14 PF13173.1 EIW86375.1 - 2.8e-07 30.4 0.0 0.64 9.9 0.0 5.6 5 0 0 5 5 5 2 AAA domain T2SE PF00437.15 EIW86375.1 - 5.2e-07 28.8 0.0 0.016 14.1 0.0 3.7 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_16 PF13191.1 EIW86375.1 - 7.3e-07 29.3 12.5 0.14 12.1 0.2 6.8 7 1 1 8 8 6 2 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EIW86375.1 - 1.3e-06 28.0 0.0 0.13 11.7 0.0 4.1 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_19 PF13245.1 EIW86375.1 - 1.5e-06 27.8 0.1 0.87 9.3 0.0 4.7 4 0 0 4 4 4 1 Part of AAA domain Mg_chelatase PF01078.16 EIW86375.1 - 5.4e-06 25.7 0.4 0.5 9.5 0.0 3.7 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EIW86375.1 - 1.1e-05 25.7 3.7 0.053 13.8 0.0 5.4 6 0 0 6 6 5 1 AAA domain AAA_29 PF13555.1 EIW86375.1 - 0.00024 20.5 0.0 0.69 9.4 0.0 3.6 3 0 0 3 3 3 1 P-loop containing region of AAA domain IstB_IS21 PF01695.12 EIW86375.1 - 0.0013 18.1 0.8 0.37 10.1 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EIW86375.1 - 0.0035 16.4 2.6 2.3 7.2 0.0 4.6 5 0 0 5 5 5 1 Zeta toxin ABC_tran PF00005.22 EIW86375.1 - 0.0047 17.2 2.8 9.9 6.4 0.0 4.6 4 0 0 4 4 3 0 ABC transporter AAA_25 PF13481.1 EIW86375.1 - 0.011 15.1 1.5 1.6 8.0 0.0 4.2 5 0 0 5 5 4 0 AAA domain RNA_helicase PF00910.17 EIW86375.1 - 0.012 15.7 0.0 56 3.9 0.0 4.9 5 0 0 5 5 5 0 RNA helicase PduV-EutP PF10662.4 EIW86375.1 - 0.019 14.4 0.3 6.9 6.1 0.0 3.4 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.10 EIW86375.1 - 0.07 12.9 1.8 3.2 7.5 0.0 4.0 5 0 0 5 5 4 0 Type III restriction enzyme, res subunit MobB PF03205.9 EIW86375.1 - 0.078 12.6 0.1 24 4.5 0.0 3.6 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B Abi_C PF14355.1 EIW86375.1 - 0.15 12.0 0.0 35 4.4 0.0 3.3 2 0 0 2 2 2 0 Abortive infection C-terminus Reo_sigmaC PF04582.7 EIW86375.1 - 1.4 8.0 5.8 1.1 8.3 0.6 2.9 3 0 0 3 3 3 0 Reovirus sigma C capsid protein PLRV_ORF5 PF01690.12 EIW86375.1 - 2.2 7.3 1.5 4.4 6.3 1.1 1.4 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein AAA_10 PF12846.2 EIW86375.1 - 3.8 6.8 11.5 9.1 5.6 0.2 5.0 5 0 0 5 5 5 0 AAA-like domain Pex2_Pex12 PF04757.9 EIW86376.1 - 1.4e-24 86.8 3.4 2.3e-24 86.0 2.4 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.1 EIW86376.1 - 3.1e-09 36.3 6.5 4.3e-09 35.9 4.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW86376.1 - 2.6e-08 33.5 11.1 4.1e-08 32.9 7.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EIW86376.1 - 2.8e-08 33.6 10.5 4.4e-08 33.0 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW86376.1 - 5.5e-08 32.3 9.0 8.3e-08 31.7 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW86376.1 - 1.1e-06 28.2 9.0 1.6e-06 27.7 6.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EIW86376.1 - 0.00031 20.7 3.6 0.0006 19.8 2.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EIW86376.1 - 0.0048 16.7 9.7 0.0088 15.8 6.8 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EIW86376.1 - 0.0089 15.8 2.0 0.016 15.0 1.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EIW86376.1 - 0.022 14.4 2.5 0.022 14.4 1.7 1.8 1 1 1 2 2 2 0 RING-type zinc-finger TerY-C PF15616.1 EIW86376.1 - 0.4 10.6 7.0 0.78 9.6 4.8 1.5 1 1 0 1 1 1 0 TerY-C metal binding domain zf-RING_4 PF14570.1 EIW86376.1 - 0.45 10.1 8.8 0.86 9.2 6.1 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 EIW86376.1 - 0.45 10.3 5.4 0.81 9.5 3.7 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Romo1 PF10247.4 EIW86377.1 - 5e-25 87.4 6.3 6.8e-25 87.0 4.3 1.2 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_YMGG PF13441.1 EIW86377.1 - 0.047 13.2 1.1 0.075 12.5 0.7 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper L51_S25_CI-B8 PF05047.11 EIW86378.1 - 7.2e-11 41.6 0.1 1.4e-10 40.6 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain HLH PF00010.21 EIW86380.1 - 0.0023 17.5 0.5 0.36 10.5 0.0 3.4 3 0 0 3 3 3 2 Helix-loop-helix DNA-binding domain MFS_1 PF07690.11 EIW86381.1 - 1.2e-46 159.0 29.1 1e-26 93.5 7.6 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.14 EIW86381.1 - 0.0035 15.9 11.2 0.01 14.4 2.5 3.0 3 0 0 3 3 3 2 LacY proton/sugar symporter MFS_1_like PF12832.2 EIW86381.1 - 0.12 12.1 3.0 0.37 10.5 0.0 3.1 3 0 0 3 3 3 0 MFS_1 like family H2TH PF06831.9 EIW86382.1 - 1e-21 76.4 0.0 2e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.19 EIW86382.1 - 1.8e-06 28.3 0.1 3e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase N-terminal domain FbpA PF05833.6 EIW86382.1 - 0.043 12.3 0.0 0.059 11.9 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HATPase_c PF02518.21 EIW86383.1 - 7.1e-25 86.8 0.0 1.7e-24 85.6 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EIW86383.1 - 6.3e-21 74.4 0.0 1.1e-19 70.4 0.0 2.8 2 0 0 2 2 2 1 Response regulator receiver domain AAA_16 PF13191.1 EIW86383.1 - 7.9e-17 61.8 1.8 3.2e-16 59.8 0.2 2.8 3 0 0 3 3 3 1 AAA ATPase domain HisKA PF00512.20 EIW86383.1 - 1.8e-15 56.6 0.5 1.2e-14 54.0 0.0 2.7 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain GAF_2 PF13185.1 EIW86383.1 - 1.1e-08 35.7 0.0 2.9e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EIW86383.1 - 6.7e-06 26.2 0.0 1.7e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 GAF domain Arch_ATPase PF01637.13 EIW86383.1 - 5.6e-05 22.9 1.9 0.0062 16.2 0.1 3.2 4 0 0 4 4 4 1 Archaeal ATPase Pkinase PF00069.20 EIW86383.1 - 7.9e-05 21.9 0.0 0.00016 20.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain TPR_11 PF13414.1 EIW86383.1 - 0.0018 17.8 0.5 0.54 9.9 0.0 3.1 3 0 0 3 3 3 1 TPR repeat AAA_22 PF13401.1 EIW86383.1 - 0.015 15.4 0.0 0.13 12.4 0.0 2.6 1 1 0 1 1 1 0 AAA domain BCDHK_Adom3 PF10436.4 EIW86383.1 - 0.035 13.6 0.3 0.16 11.4 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase NACHT PF05729.7 EIW86383.1 - 0.045 13.4 1.0 0.2 11.3 0.7 2.2 1 1 0 1 1 1 0 NACHT domain DUF258 PF03193.11 EIW86383.1 - 0.094 11.9 0.0 0.24 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DUF1986 PF09342.6 EIW86383.1 - 0.095 11.9 0.0 2.8 7.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1986) DEAD PF00270.24 EIW86384.1 - 7.4e-37 126.4 0.1 1.3e-36 125.6 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW86384.1 - 1.1e-24 86.1 0.0 1e-23 82.9 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW86384.1 - 4.4e-05 23.3 0.0 8.2e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Mito_carr PF00153.22 EIW86385.1 - 8.9e-60 198.4 3.6 1.3e-19 69.6 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein ATP-synt_ab_N PF02874.18 EIW86385.1 - 0.12 12.5 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 ATP synthase alpha/beta family, beta-barrel domain DEAD PF00270.24 EIW86386.1 - 1.3e-37 128.8 0.1 2.6e-37 127.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW86386.1 - 2.6e-23 81.6 0.2 7.5e-23 80.1 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW86386.1 - 2.9e-06 27.2 0.0 4.9e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIW86386.1 - 1.2 9.3 3.2 9.3 6.4 2.2 2.2 1 1 0 1 1 1 0 AAA domain ING PF12998.2 EIW86387.1 - 1.3e-16 60.8 1.3 1.9e-16 60.2 0.9 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EIW86387.1 - 3.1e-09 36.3 7.3 5.6e-09 35.5 5.0 1.4 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EIW86387.1 - 0.018 15.2 0.1 0.046 13.8 0.1 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain Gag_p19 PF02228.11 EIW86387.1 - 0.027 14.7 0.1 0.051 13.8 0.0 1.4 1 0 0 1 1 1 0 Major core protein p19 FlgN PF05130.7 EIW86387.1 - 0.094 12.9 2.6 0.18 12.0 1.8 1.4 1 0 0 1 1 1 0 FlgN protein NUC130_3NT PF08158.7 EIW86387.1 - 0.14 12.4 0.4 1.2 9.4 0.2 2.2 2 0 0 2 2 2 0 NUC130/3NT domain zf-RING-like PF08746.6 EIW86387.1 - 0.36 10.8 3.7 0.67 9.9 1.1 2.3 2 0 0 2 2 2 0 RING-like domain HMG_box PF00505.14 EIW86388.1 - 7.7e-06 26.0 1.6 4e-05 23.8 1.1 2.0 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIW86388.1 - 0.073 13.4 0.0 0.15 12.4 0.0 1.5 1 0 0 1 1 1 0 HMG-box domain tRNA_NucTran2_2 PF13735.1 EIW86389.1 - 0.028 14.2 0.0 0.035 13.9 0.0 1.2 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative PolyA_pol PF01743.15 EIW86390.1 - 5.7e-23 81.5 0.0 9.4e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EIW86390.1 - 0.00056 19.4 0.0 0.0017 17.8 0.0 1.9 1 1 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Abhydrolase_2 PF02230.11 EIW86391.1 - 4.4e-47 160.3 0.0 5.4e-47 160.0 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EIW86391.1 - 2.3e-11 43.6 0.0 2.9e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW86391.1 - 3e-07 30.5 0.8 7.6e-05 22.6 0.4 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 EIW86391.1 - 0.012 15.0 0.0 0.41 10.0 0.0 2.3 1 1 0 1 1 1 0 Serine hydrolase (FSH1) PAF-AH_p_II PF03403.8 EIW86391.1 - 0.12 10.6 0.0 0.43 8.8 0.0 1.8 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Arm PF00514.18 EIW86392.1 - 3.6e-64 210.5 33.7 2.5e-12 46.1 0.1 11.3 10 2 2 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EIW86392.1 - 3e-23 81.8 11.3 1.4e-05 25.2 0.1 7.4 2 2 3 6 6 6 6 HEAT repeats HEAT PF02985.17 EIW86392.1 - 2e-17 61.5 16.2 0.13 12.4 0.0 9.7 9 0 0 9 9 9 5 HEAT repeat HEAT_EZ PF13513.1 EIW86392.1 - 2.8e-14 53.1 14.0 0.0028 18.1 0.3 7.9 5 2 4 9 9 9 4 HEAT-like repeat Arm_2 PF04826.8 EIW86392.1 - 4.2e-10 39.1 11.3 2e-06 27.0 2.5 3.3 1 1 0 3 3 3 2 Armadillo-like KAP PF05804.7 EIW86392.1 - 5.7e-09 34.4 1.7 8.3e-09 33.9 1.2 1.2 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) Adaptin_N PF01602.15 EIW86392.1 - 1.4e-08 33.5 12.1 3.6e-07 28.8 0.2 2.4 2 1 1 3 3 3 2 Adaptin N terminal region V-ATPase_H_N PF03224.9 EIW86392.1 - 1.1e-06 28.0 9.4 0.00042 19.5 0.3 4.0 2 1 2 4 4 4 2 V-ATPase subunit H Vac14_Fab1_bd PF12755.2 EIW86392.1 - 0.0066 16.8 0.2 5.8 7.3 0.0 3.5 2 1 2 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_PBS PF03130.11 EIW86392.1 - 0.029 14.8 12.7 13 6.6 0.3 7.2 7 0 0 7 7 7 0 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.3 EIW86392.1 - 0.05 13.5 4.4 9.8 6.1 0.0 4.3 2 1 3 5 5 5 0 V-ATPase subunit H Glyco_hydro_16 PF00722.16 EIW86393.1 - 2.2e-09 36.8 0.3 6.4e-09 35.3 0.2 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 AF-4 PF05110.8 EIW86393.1 - 0.59 7.9 6.8 0.84 7.4 4.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein BAG PF02179.11 EIW86394.1 - 1.2e-05 25.3 0.1 1.2e-05 25.3 0.0 2.4 2 0 0 2 2 2 1 BAG domain Transketolase_N PF00456.16 EIW86394.1 - 6.9 5.3 9.0 2.3 6.9 0.8 2.3 2 0 0 2 2 2 0 Transketolase, thiamine diphosphate binding domain GYF PF02213.11 EIW86395.1 - 6.7e-14 51.2 0.0 1.3e-13 50.2 0.0 1.5 1 0 0 1 1 1 1 GYF domain Acatn PF13000.2 EIW86396.1 - 1.4e-128 429.8 28.4 1.9e-59 201.6 12.2 3.5 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 p450 PF00067.17 EIW86397.1 - 6.9e-69 232.5 0.0 8.7e-69 232.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 KH_1 PF00013.24 EIW86397.1 - 0.079 12.6 0.1 0.2 11.3 0.1 1.7 1 0 0 1 1 1 0 KH domain KH_3 PF13014.1 EIW86397.1 - 0.097 12.3 0.8 0.26 11.0 0.5 1.6 1 0 0 1 1 1 0 KH domain KH_2 PF07650.12 EIW86397.1 - 0.12 11.9 0.3 0.24 10.9 0.2 1.4 1 0 0 1 1 1 0 KH domain DUF913 PF06025.7 EIW86397.1 - 0.15 10.7 0.0 0.22 10.2 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NAP PF00956.13 EIW86398.1 - 1.4e-30 106.1 4.6 4.3e-30 104.6 3.2 1.8 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) DUF4611 PF15387.1 EIW86398.1 - 0.014 15.5 3.1 0.014 15.5 2.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 EIW86398.1 - 0.16 11.4 4.7 0.28 10.6 3.3 1.5 1 0 0 1 1 1 0 Nucleoplasmin Syja_N PF02383.13 EIW86399.1 - 6.4e-88 294.5 0.0 1.7e-87 293.1 0.0 1.6 2 0 0 2 2 2 1 SacI homology domain LRR_9 PF14580.1 EIW86400.1 - 2e-59 200.0 0.1 3.1e-59 199.4 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 EIW86400.1 - 7.4e-13 47.7 12.9 2.3e-07 30.2 3.2 3.4 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW86400.1 - 1e-08 34.7 5.9 4e-06 26.4 0.4 2.9 2 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EIW86400.1 - 0.00093 18.9 8.1 8.2 6.8 0.1 5.3 5 1 1 6 6 6 2 Leucine Rich Repeat LRR_7 PF13504.1 EIW86400.1 - 0.0011 18.7 5.3 11 6.6 0.1 4.7 5 0 0 5 5 5 1 Leucine rich repeat LRR_6 PF13516.1 EIW86400.1 - 0.12 12.4 8.3 16 5.9 2.0 4.5 4 1 0 4 4 4 0 Leucine Rich repeat MitMem_reg PF13012.1 EIW86401.1 - 7.5e-19 67.9 0.1 1.2e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EIW86401.1 - 6.1e-11 42.0 0.0 1.3e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease NOSIC PF08060.8 EIW86401.1 - 0.14 11.9 0.1 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 NOSIC (NUC001) domain MCM PF00493.18 EIW86402.1 - 2.9e-141 470.0 0.1 3.9e-141 469.6 0.1 1.1 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EIW86402.1 - 7.5e-17 61.9 0.3 1.8e-16 60.7 0.1 1.8 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EIW86402.1 - 5.4e-07 28.9 0.0 0.00024 20.3 0.0 2.7 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EIW86402.1 - 0.0001 22.0 0.0 0.00026 20.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EIW86402.1 - 0.00031 20.3 0.1 0.0037 16.8 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 EIW86402.1 - 0.0078 16.5 0.4 0.061 13.7 0.1 2.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA PF00004.24 EIW86402.1 - 0.045 13.9 0.0 0.15 12.2 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EIW86402.1 - 0.11 11.9 0.0 5.7 6.3 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain SprT-like PF10263.4 EIW86403.1 - 8.8e-44 148.9 1.4 1.4e-43 148.2 1.0 1.3 1 0 0 1 1 1 1 SprT-like family Zn-ribbon_8 PF09723.5 EIW86403.1 - 0.0045 16.9 3.0 0.013 15.4 2.1 1.8 1 0 0 1 1 1 1 Zinc ribbon domain p450 PF00067.17 EIW86404.1 - 6.3e-55 186.5 0.0 3e-53 180.9 0.0 2.7 1 1 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 EIW86405.1 - 5.2e-43 147.0 0.0 1.8e-23 83.0 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW86405.1 - 3.9e-14 52.3 0.0 2.1e-09 36.8 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EIW86405.1 - 0.08 11.7 0.1 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 EIW86406.1 - 7.2e-52 176.0 0.0 4.6e-51 173.4 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW86406.1 - 1.8e-36 125.5 0.0 2e-21 76.2 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIW86406.1 - 0.017 14.1 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Rieske PF00355.21 EIW86407.1 - 1.1e-16 60.2 0.3 2.9e-16 58.8 0.2 1.8 1 1 1 2 2 2 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 EIW86407.1 - 2.5e-16 59.6 1.5 4.5e-16 58.8 1.1 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region GDPD PF03009.12 EIW86408.1 - 1.9e-33 116.0 0.0 2.4e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EIW86408.1 - 6.3e-06 26.2 0.8 1.8e-05 24.7 0.2 2.1 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family CHCH PF06747.8 EIW86409.1 - 1.8e-07 30.9 3.5 2.5e-07 30.4 2.4 1.2 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EIW86409.1 - 0.015 15.3 2.3 0.027 14.5 1.6 1.4 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 GCK PF07802.6 EIW86409.1 - 0.024 14.7 0.9 0.034 14.2 0.6 1.2 1 0 0 1 1 1 0 GCK domain NDUF_B7 PF05676.8 EIW86409.1 - 0.035 13.5 0.2 0.046 13.1 0.2 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX6B PF02297.12 EIW86409.1 - 0.047 13.7 0.5 0.066 13.2 0.3 1.2 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb UPF0203 PF05254.7 EIW86409.1 - 0.28 11.0 2.2 2.3 8.1 0.3 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) bZIP_2 PF07716.10 EIW86410.1 - 1.2e-08 34.6 7.7 2e-07 30.7 5.3 2.2 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_1 PF00170.16 EIW86410.1 - 5.7e-06 26.1 7.6 2.3e-05 24.2 5.3 1.8 1 1 0 1 1 1 1 bZIP transcription factor DUF2205 PF10224.4 EIW86410.1 - 0.064 12.8 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) bZIP_Maf PF03131.12 EIW86410.1 - 1.3 9.3 5.6 0.16 12.2 1.1 1.5 2 0 0 2 2 2 0 bZIP Maf transcription factor NPL4 PF05021.10 EIW86411.1 - 1.1e-100 336.7 0.0 1.4e-100 336.4 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EIW86411.1 - 3.3e-61 205.2 0.0 5.4e-61 204.5 0.0 1.3 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EIW86411.1 - 0.0014 18.8 0.0 0.028 14.7 0.0 2.3 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 Ferritin_2 PF13668.1 EIW86411.1 - 0.07 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Ferritin-like domain NUDIX PF00293.23 EIW86412.1 - 1e-09 38.1 0.0 1.8e-09 37.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Exo_endo_phos PF03372.18 EIW86414.1 - 9e-11 42.1 0.3 1.3e-10 41.6 0.2 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EIW86414.1 - 4.3e-06 26.3 0.0 1.1e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase RVT_1 PF00078.22 EIW86415.1 - 1.6e-05 24.3 0.0 2.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.1 EIW86416.1 - 0.0039 17.4 1.7 0.012 15.9 1.2 1.8 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase Yippee-Mis18 PF03226.9 EIW86417.1 - 1.4e-22 79.4 0.1 1.7e-22 79.2 0.1 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GFA PF04828.9 EIW86417.1 - 0.09 12.7 2.2 1 9.3 0.1 2.1 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_recom PF13408.1 EIW86417.1 - 2.7 8.3 6.5 3.3 8.0 1.0 2.2 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Ras PF00071.17 EIW86419.1 - 7.8e-51 171.6 0.2 8.9e-51 171.4 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW86419.1 - 2.4e-15 57.0 0.0 3.2e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW86419.1 - 1.9e-05 24.0 0.1 2.1e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIW86419.1 - 0.00015 21.2 0.0 0.00037 19.9 0.0 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIW86419.1 - 0.00034 20.5 0.0 0.00043 20.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.1 EIW86419.1 - 0.04 13.4 0.1 0.061 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.7 EIW86419.1 - 0.047 12.8 0.0 0.057 12.5 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Tim17 PF02466.14 EIW86420.1 - 2.4e-22 79.3 0.1 4.3e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Complex1_30kDa PF00329.14 EIW86422.1 - 1.2e-35 121.8 0.0 1.9e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit BCAS2 PF05700.6 EIW86423.1 - 1.8e-60 204.1 8.1 2.4e-60 203.7 5.6 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) CALCOCO1 PF07888.6 EIW86423.1 - 0.013 13.8 4.3 0.016 13.5 3.0 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Acyl-CoA_dh_C PF12806.2 EIW86423.1 - 0.019 14.8 1.1 0.027 14.3 0.5 1.5 1 1 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like CCDC155 PF14662.1 EIW86423.1 - 0.019 14.5 9.2 0.029 13.9 6.4 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 APG6 PF04111.7 EIW86423.1 - 1.2 8.1 9.6 0.21 10.5 4.0 1.6 1 1 0 1 1 1 0 Autophagy protein Apg6 Kinetocho_Slk19 PF12709.2 EIW86423.1 - 3 8.0 9.5 19 5.4 1.3 3.2 1 1 2 3 3 3 0 Central kinetochore-associated IncA PF04156.9 EIW86423.1 - 3.5 7.1 11.6 2.2 7.8 0.6 2.2 1 1 1 2 2 2 0 IncA protein OmpH PF03938.9 EIW86424.1 - 2 8.3 8.1 3.5 7.5 5.6 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) ATP-grasp_2 PF08442.5 EIW86425.1 - 1e-73 247.0 0.1 1.8e-73 246.2 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EIW86425.1 - 8.6e-27 93.6 0.1 1.5e-26 92.8 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EIW86425.1 - 5.5e-13 48.6 0.1 5.8e-12 45.2 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain GARS_A PF01071.14 EIW86425.1 - 3.4e-05 23.4 0.1 0.00063 19.3 0.0 2.3 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 EIW86425.1 - 0.0015 18.2 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 EIW86425.1 - 0.086 12.1 0.1 0.34 10.2 0.0 2.0 2 0 0 2 2 2 0 ATP-grasp domain DinB_2 PF12867.2 EIW86426.1 - 1.6e-08 34.9 0.2 2e-08 34.6 0.2 1.1 1 0 0 1 1 1 1 DinB superfamily Hist_deacetyl PF00850.14 EIW86427.1 - 1.5e-84 283.9 0.0 2.3e-84 283.3 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain XPA_C PF05181.7 EIW86428.1 - 3.5e-28 96.9 2.5 3.5e-28 96.9 1.7 1.9 2 0 0 2 2 2 1 XPA protein C-terminus 4HBT_3 PF13622.1 EIW86428.1 - 1.3e-23 84.0 3.4 1.3e-22 80.7 0.0 3.0 2 1 0 2 2 2 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EIW86428.1 - 3.7e-09 36.2 0.0 0.0093 15.5 0.0 4.2 2 2 2 4 4 4 4 Acyl-CoA thioesterase XPA_N PF01286.13 EIW86428.1 - 0.0035 16.9 5.6 0.0079 15.8 3.9 1.6 1 0 0 1 1 1 1 XPA protein N-terminal Ribosomal_S27e PF01667.12 EIW86429.1 - 8.2e-30 102.1 3.9 9.9e-30 101.8 2.7 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EIW86429.1 - 0.0061 16.4 1.4 0.0074 16.1 1.0 1.2 1 0 0 1 1 1 1 IBR domain Zn_Tnp_IS1 PF03811.8 EIW86429.1 - 0.46 10.0 2.5 0.93 9.0 1.2 1.9 1 1 1 2 2 2 0 InsA N-terminal domain BTG PF07742.7 EIW86430.1 - 1.9e-11 43.4 0.0 3e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 BTG family RAP1 PF07218.6 EIW86430.1 - 4.9 5.1 5.6 5.8 4.8 3.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BATS PF06968.8 EIW86431.1 - 3.5e-25 87.6 0.0 7.7e-25 86.5 0.0 1.6 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EIW86431.1 - 2.3e-16 60.4 0.1 3.5e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Radical SAM superfamily DUF1565 PF07602.6 EIW86431.1 - 0.06 12.4 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1565) DUF3437 PF11919.3 EIW86433.1 - 4.7e-27 93.5 0.1 4.7e-27 93.5 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) HEAT PF02985.17 EIW86433.1 - 7.5e-08 31.8 3.4 0.048 13.7 0.0 6.6 7 0 0 7 7 7 2 HEAT repeat HEAT_2 PF13646.1 EIW86433.1 - 1.5e-05 25.1 6.4 0.16 12.2 0.0 6.4 8 0 0 8 8 8 2 HEAT repeats HD_assoc PF13286.1 EIW86433.1 - 0.0011 19.1 0.0 0.032 14.4 0.0 2.9 2 0 0 2 2 2 1 Phosphohydrolase-associated domain UPF0149 PF03695.8 EIW86433.1 - 0.019 14.8 2.5 0.47 10.3 0.1 3.4 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0149) DcpS_C PF11969.3 EIW86434.1 - 4.3e-06 26.9 0.0 7.1e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Translin PF01997.11 EIW86435.1 - 9e-32 110.2 0.0 1.9e-28 99.4 0.0 2.1 1 1 1 2 2 2 2 Translin family zf-C3HC4 PF00097.20 EIW86436.1 - 9.6e-08 31.5 7.8 2.1e-07 30.4 5.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EIW86436.1 - 1e-07 31.8 10.4 1e-07 31.8 7.2 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW86436.1 - 8.2e-07 28.5 8.7 8.2e-07 28.5 6.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW86436.1 - 9.7e-07 28.5 10.1 9.7e-07 28.5 7.0 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EIW86436.1 - 0.0013 18.4 8.6 0.0032 17.1 5.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EIW86436.1 - 0.0016 18.2 3.4 0.075 12.8 2.9 2.5 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Baculo_IE-1 PF05290.6 EIW86436.1 - 0.0065 16.2 1.1 0.01 15.5 0.7 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.1 EIW86436.1 - 0.0065 16.3 10.5 0.014 15.2 7.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-MIZ PF02891.15 EIW86436.1 - 0.028 13.9 8.1 0.061 12.8 5.6 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger GAGA PF09237.6 EIW86436.1 - 0.15 11.6 0.1 0.15 11.6 0.1 2.2 2 0 0 2 2 2 0 GAGA factor zf-rbx1 PF12678.2 EIW86436.1 - 0.27 11.3 8.2 0.43 10.7 4.3 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EIW86436.1 - 1.3 8.7 6.7 1.4 8.6 1.2 2.6 2 0 0 2 2 2 0 RING-type zinc-finger DZR PF12773.2 EIW86436.1 - 1.3 8.8 8.0 4.2 7.2 5.6 1.8 1 1 0 1 1 1 0 Double zinc ribbon Rad50_zn_hook PF04423.9 EIW86436.1 - 3.9 7.0 6.1 0.45 10.0 0.2 2.2 2 0 0 2 2 2 0 Rad50 zinc hook motif DNA_pol_A_exo1 PF01612.15 EIW86438.1 - 1.3e-17 63.8 0.0 1.8e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 3'-5' exonuclease CBM_5_12 PF02839.9 EIW86439.1 - 5.1e-14 51.5 29.1 2.2e-10 39.9 9.9 4.2 5 0 0 5 5 5 2 Carbohydrate binding domain CBM_5_12_2 PF14600.1 EIW86439.1 - 2.8e-07 30.0 21.9 4.5e-05 22.9 4.8 3.1 3 0 0 3 3 3 2 Cellulose-binding domain Pkinase PF00069.20 EIW86440.1 - 1.3e-59 201.4 0.1 1.5e-59 201.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW86440.1 - 1.5e-19 70.1 0.0 2.2e-19 69.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW86440.1 - 2.1e-07 30.9 0.0 1.4e-05 24.9 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EIW86440.1 - 0.011 15.3 0.1 0.026 14.0 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kdo PF06293.9 EIW86440.1 - 0.033 13.2 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EIW86440.1 - 0.11 11.8 0.2 7.1 5.9 0.0 2.4 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL SET PF00856.23 EIW86441.1 - 3.6e-07 30.6 0.0 1.6e-05 25.2 0.0 2.2 1 1 0 1 1 1 1 SET domain tRNA_anti-codon PF01336.20 EIW86441.1 - 0.1 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain CTDII PF01556.13 EIW86442.1 - 9.7e-28 95.8 0.1 7.9e-22 76.9 0.0 2.4 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ PF00226.26 EIW86442.1 - 2e-23 81.9 3.4 3.2e-23 81.2 2.3 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EIW86442.1 - 1.5e-09 37.7 15.3 1.5e-09 37.7 10.6 1.9 2 0 0 2 2 2 1 DnaJ central domain MFS_1 PF07690.11 EIW86443.1 - 7.3e-34 117.0 52.4 2.5e-33 115.2 34.2 2.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Choline_kinase PF01633.15 EIW86444.1 - 1.8e-50 171.4 0.0 2.3e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EIW86444.1 - 3.9e-09 36.6 0.0 5.9e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EIW86444.1 - 0.0016 17.6 0.1 0.0024 17.0 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase DUF656 PF04920.7 EIW86444.1 - 0.11 12.2 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF656) zf-CCCH PF00642.19 EIW86445.1 - 9.8e-20 69.7 14.5 3.5e-11 42.5 2.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SGT1 PF07093.6 EIW86446.1 - 8.3e-134 447.1 26.5 1.1e-124 416.9 3.4 2.0 2 0 0 2 2 2 2 SGT1 protein Peptidase_C4 PF00863.14 EIW86446.1 - 0.021 13.7 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C4 TIM21 PF08294.6 EIW86447.1 - 4.3e-23 81.5 0.0 4.8e-21 74.9 0.0 2.3 2 0 0 2 2 2 2 TIM21 Histone PF00125.19 EIW86448.1 - 4.1e-30 103.7 0.8 6.7e-30 103.0 0.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIW86448.1 - 1.3e-05 25.2 0.1 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EIW86448.1 - 0.00072 19.5 1.3 0.0014 18.6 0.1 1.9 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EIW86448.1 - 0.015 14.9 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EIW86448.1 - 0.11 11.6 1.1 0.14 11.4 0.8 1.3 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Chalcone PF02431.10 EIW86449.1 - 3.6e-30 104.8 0.0 5.1e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Alpha_TIF PF02232.10 EIW86449.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Alpha trans-inducing protein (Alpha-TIF) DUF3437 PF11919.3 EIW86450.1 - 1.3e-31 108.1 0.3 6.7e-31 105.8 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3437) HEAT PF02985.17 EIW86450.1 - 5.2e-08 32.3 4.1 0.0013 18.5 0.1 5.5 4 0 0 4 4 4 1 HEAT repeat HEAT_EZ PF13513.1 EIW86450.1 - 0.00018 21.8 0.7 0.34 11.4 0.0 4.4 3 0 0 3 3 3 1 HEAT-like repeat Cnd1 PF12717.2 EIW86450.1 - 0.00028 20.7 0.0 0.18 11.6 0.1 3.4 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EIW86450.1 - 0.00058 20.0 3.6 0.51 10.6 0.0 5.0 6 0 0 6 6 6 1 HEAT repeats Arm PF00514.18 EIW86450.1 - 0.088 12.6 3.4 0.95 9.3 0.1 3.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Clat_adaptor_s PF01217.15 EIW86451.1 - 5.6e-44 149.3 0.2 3.8e-43 146.6 0.1 1.9 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Med6 PF04934.9 EIW86452.1 - 7.5e-39 132.4 0.4 1.1e-38 131.9 0.3 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component Catalase PF00199.14 EIW86453.1 - 4.4e-166 552.3 0.3 5.7e-166 551.9 0.2 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EIW86453.1 - 4.3e-19 68.1 0.1 1.1e-18 66.8 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EIW86453.1 - 4.8e-11 42.3 0.0 8.9e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DUF3666 PF12408.3 EIW86453.1 - 0.025 13.6 0.4 0.064 12.3 0.1 1.8 2 0 0 2 2 2 0 Ribose-5-phosphate isomerase zf-C2H2_4 PF13894.1 EIW86454.1 - 3.9e-09 36.1 9.4 1.7e-05 24.7 0.4 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EIW86454.1 - 1.3e-08 34.6 20.0 8.4e-07 28.9 0.5 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW86454.1 - 1.7e-05 24.8 14.1 0.0021 18.2 1.5 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EIW86454.1 - 0.035 14.2 0.1 0.035 14.2 0.1 3.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EIW86454.1 - 0.12 12.5 4.5 0.26 11.4 3.1 1.6 1 1 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 EIW86454.1 - 3.7 7.9 6.3 1 9.6 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain SUR7 PF06687.7 EIW86455.1 - 1.5e-18 67.1 12.3 1.8e-18 66.8 8.5 1.1 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EIW86455.1 - 0.0041 16.8 11.3 0.0041 16.8 7.9 2.1 2 1 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 EIW86455.1 - 0.0051 16.4 5.1 0.0051 16.4 3.5 2.1 3 0 0 3 3 3 1 PMP-22/EMP/MP20/Claudin family LEAP-2 PF07359.6 EIW86455.1 - 0.12 12.0 0.4 0.28 10.8 0.3 1.5 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) DUF3541 PF12060.3 EIW86455.1 - 0.18 11.1 0.1 0.61 9.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3541) DUF1469 PF07332.6 EIW86455.1 - 4.7 6.9 20.7 0.087 12.5 4.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) Fig1 PF12351.3 EIW86455.1 - 6.2 6.6 16.9 1.3 8.9 7.9 2.1 2 1 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Glyco_transf_28 PF03033.15 EIW86456.1 - 5.3e-27 94.2 0.0 1e-26 93.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain GRAM PF02893.15 EIW86456.1 - 6.1e-19 67.3 1.8 8.5e-11 41.2 0.2 3.5 3 0 0 3 3 3 2 GRAM domain PH PF00169.24 EIW86456.1 - 5.2e-13 49.0 0.5 5e-11 42.7 0.2 3.0 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 EIW86456.1 - 0.0001 22.5 2.0 0.0041 17.3 1.4 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain UDPGT PF00201.13 EIW86456.1 - 0.00044 18.9 0.0 0.00099 17.7 0.0 1.5 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PH_8 PF15409.1 EIW86456.1 - 0.01 15.8 0.1 0.022 14.8 0.1 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Glyco_trans_1_3 PF13528.1 EIW86456.1 - 0.021 14.0 0.0 0.67 9.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 1 PH_6 PF15406.1 EIW86456.1 - 0.09 12.8 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 Pleckstrin homology domain Glyco_tran_28_C PF04101.11 EIW86456.1 - 0.35 10.5 0.0 0.75 9.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.13 EIW86457.1 - 0.00028 19.5 0.0 0.00043 18.9 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EIW86457.1 - 0.043 13.4 0.0 0.06 13.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EIW86457.1 - 0.052 12.7 0.0 0.074 12.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 1 DIOX_N PF14226.1 EIW86458.1 - 0.00067 20.1 0.0 0.0025 18.3 0.0 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIW86458.1 - 0.0011 19.2 0.0 0.002 18.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RIC1 PF07064.8 EIW86459.1 - 2.1e-80 269.8 0.6 2.9e-80 269.4 0.4 1.2 1 0 0 1 1 1 1 RIC1 PD40 PF07676.7 EIW86459.1 - 9.1e-05 22.0 0.0 0.77 9.4 0.0 2.8 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat PRELI PF04707.9 EIW86460.1 - 4e-32 110.9 0.0 5.1e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family TGS PF02824.16 EIW86461.1 - 1.7e-19 69.3 0.0 3.3e-19 68.4 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EIW86461.1 - 2.2e-19 69.4 0.1 4.4e-19 68.5 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIW86461.1 - 7.7e-12 44.7 0.0 1.4e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EIW86461.1 - 0.00029 21.3 0.0 0.0011 19.4 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EIW86461.1 - 0.0013 18.6 0.2 0.035 13.9 0.0 2.3 1 1 1 2 2 2 1 Dynamin family MCM PF00493.18 EIW86461.1 - 0.049 12.4 0.1 0.14 10.9 0.0 1.7 2 0 0 2 2 2 0 MCM2/3/5 family Pkinase PF00069.20 EIW86462.1 - 2.7e-64 216.8 0.0 5.1e-64 215.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW86462.1 - 1.5e-35 122.5 0.0 1.2e-26 93.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EIW86462.1 - 1.8e-07 30.4 0.1 1.3e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EIW86462.1 - 0.034 12.9 0.0 0.061 12.1 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 CDC37_N PF03234.9 EIW86463.1 - 0.066 13.5 0.9 0.1 12.9 0.6 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Tetraspannin PF00335.15 EIW86463.1 - 7.7 5.7 25.9 12 5.1 0.0 4.0 2 1 1 3 3 3 0 Tetraspanin family B-block_TFIIIC PF04182.7 EIW86464.1 - 2.8e-10 39.8 0.5 2.4e-08 33.6 0.0 3.5 3 1 1 4 4 4 1 B-block binding subunit of TFIIIC HTH_24 PF13412.1 EIW86464.1 - 0.031 13.6 0.0 0.54 9.6 0.0 2.7 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding AT_hook PF02178.14 EIW86464.1 - 0.23 11.2 18.5 0.44 10.3 3.4 3.2 2 0 0 2 2 2 0 AT hook motif TFIIB PF00382.14 EIW86465.1 - 4.6e-39 132.0 0.5 1.4e-18 66.4 0.1 2.4 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EIW86465.1 - 2.8e-24 85.1 2.6 2.8e-24 85.1 1.8 2.7 2 1 0 2 2 2 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 EIW86465.1 - 2e-06 27.3 0.3 0.042 13.3 0.1 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain TF_Zn_Ribbon PF08271.7 EIW86465.1 - 3.2e-06 26.3 5.0 8.4e-06 25.0 3.4 1.8 1 0 0 1 1 1 1 TFIIB zinc-binding A2L_zn_ribbon PF08792.5 EIW86465.1 - 0.043 13.2 2.1 0.084 12.3 1.5 1.5 1 0 0 1 1 1 0 A2L zinc ribbon domain RRN7 PF11781.3 EIW86465.1 - 0.17 11.3 1.8 0.32 10.5 1.3 1.5 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 PRELI PF04707.9 EIW86466.1 - 1.7e-36 125.1 0.0 2e-36 124.9 0.0 1.0 1 0 0 1 1 1 1 PRELI-like family ABC_membrane_2 PF06472.10 EIW86467.1 - 7.4e-86 287.7 1.6 7.4e-86 287.7 1.1 1.4 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EIW86467.1 - 1.6e-17 64.0 0.0 3.3e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EIW86467.1 - 0.00022 21.3 0.0 0.00042 20.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EIW86467.1 - 0.0036 17.6 0.0 0.0093 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EIW86467.1 - 0.0058 16.1 0.0 0.016 14.7 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 EIW86467.1 - 0.064 12.4 0.0 0.29 10.3 0.0 2.0 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EIW86467.1 - 0.076 12.2 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NT5C PF06941.7 EIW86468.1 - 2.2e-10 40.3 0.0 6e-10 38.9 0.0 1.7 2 0 0 2 2 2 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) HAD_2 PF13419.1 EIW86468.1 - 0.00081 19.6 0.0 0.0024 18.1 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIW86468.1 - 0.093 13.1 0.0 0.27 11.6 0.0 1.6 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Meiosis_expr PF15163.1 EIW86468.1 - 0.14 12.4 1.4 0.24 11.7 0.3 1.8 2 0 0 2 2 2 0 Meiosis-expressed Pro_CA PF00484.14 EIW86469.1 - 4.1e-23 82.0 0.0 5e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase MCM PF00493.18 EIW86470.1 - 3.8e-125 417.0 0.0 5.7e-125 416.5 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EIW86470.1 - 3.7e-24 85.5 0.0 9.7e-24 84.1 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EIW86470.1 - 7.9e-08 31.7 0.1 1.7e-06 27.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EIW86470.1 - 0.0055 16.3 0.0 0.017 14.6 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EIW86470.1 - 0.017 14.5 0.0 0.044 13.2 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain KAP_NTPase PF07693.9 EIW86470.1 - 0.32 9.9 1.5 0.71 8.7 0.1 2.1 2 0 0 2 2 2 0 KAP family P-loop domain WD40 PF00400.27 EIW86472.1 - 3.6e-44 147.1 12.9 3e-10 39.5 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_2 PF13360.1 EIW86472.1 - 0.00035 20.1 0.0 0.022 14.2 0.0 2.4 2 1 0 2 2 2 1 PQQ-like domain Nup160 PF11715.3 EIW86472.1 - 0.027 12.5 0.5 0.6 8.1 0.4 2.6 1 1 0 1 1 1 0 Nucleoporin Nup120/160 DUF1918 PF08940.6 EIW86472.1 - 0.056 12.7 0.1 0.73 9.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) Myc_N PF01056.13 EIW86472.1 - 0.079 12.1 0.3 0.14 11.3 0.2 1.3 1 0 0 1 1 1 0 Myc amino-terminal region Myb_DNA-binding PF00249.26 EIW86473.1 - 2.2e-38 130.0 6.7 1.1e-13 51.0 0.1 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIW86473.1 - 6.1e-37 125.5 8.3 1.4e-16 60.3 0.3 4.2 2 1 2 4 4 4 3 Myb-like DNA-binding domain Prp19 PF08606.6 EIW86474.1 - 1.3e-28 98.4 1.5 2.5e-28 97.5 1.0 1.5 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 EIW86474.1 - 7.9e-17 60.4 0.5 1.1e-05 25.1 0.0 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat zf-Nse PF11789.3 EIW86474.1 - 4.3e-07 29.3 0.0 8e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 EIW86474.1 - 0.00066 19.5 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 U-box domain Rtf2 PF04641.7 EIW86474.1 - 0.0027 16.9 0.0 0.0053 15.9 0.0 1.4 1 0 0 1 1 1 1 Rtf2 RING-finger DUF3312 PF11768.3 EIW86474.1 - 0.004 15.4 0.0 0.0069 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) OPT PF03169.10 EIW86475.1 - 7.7e-178 592.7 52.5 3e-106 356.3 15.7 2.0 1 1 1 2 2 2 2 OPT oligopeptide transporter protein TauD PF02668.11 EIW86476.1 - 1.6e-51 175.4 0.6 2e-51 175.1 0.4 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family GVQW PF13900.1 EIW86476.1 - 0.19 11.7 0.5 0.45 10.5 0.0 1.8 2 0 0 2 2 2 0 Putative binding domain DIE2_ALG10 PF04922.7 EIW86477.1 - 1e-93 314.4 8.9 1.2e-93 314.1 6.2 1.1 1 0 0 1 1 1 1 DIE2/ALG10 family DUF3138 PF11336.3 EIW86478.1 - 0.61 8.1 8.2 0.92 7.6 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Spc7 PF08317.6 EIW86479.1 - 5.7e-46 156.6 8.0 7.6e-46 156.2 5.5 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 EIW86479.1 - 3.1e-05 23.5 0.0 0.00017 21.1 0.0 2.1 1 1 0 1 1 1 1 Spc7_C2 Filament PF00038.16 EIW86479.1 - 0.00016 21.2 13.0 0.00016 21.2 9.0 1.5 2 0 0 2 2 2 1 Intermediate filament protein CENP-F_leu_zip PF10473.4 EIW86479.1 - 0.0003 20.6 19.0 0.0013 18.5 1.2 2.6 2 1 1 3 3 3 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 MscS_porin PF12795.2 EIW86479.1 - 0.0019 17.6 21.0 0.0026 17.1 12.5 2.1 2 0 0 2 2 2 1 Mechanosensitive ion channel porin domain DUF3584 PF12128.3 EIW86479.1 - 0.0029 15.0 14.6 0.0043 14.4 10.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Reo_sigmaC PF04582.7 EIW86479.1 - 0.0075 15.4 0.6 0.017 14.3 0.2 1.7 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Atg14 PF10186.4 EIW86479.1 - 0.017 14.1 5.7 0.028 13.3 3.9 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 R3H-assoc PF13902.1 EIW86479.1 - 0.033 14.1 0.1 0.033 14.1 0.1 2.5 2 1 0 2 2 1 0 R3H-associated N-terminal domain Laminin_II PF06009.7 EIW86479.1 - 0.18 11.5 7.0 5.6 6.7 3.3 3.2 2 1 1 3 3 3 0 Laminin Domain II EF-hand_like PF09279.6 EIW86479.1 - 0.18 11.8 4.6 2.4 8.2 0.1 2.6 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like Macoilin PF09726.4 EIW86479.1 - 0.2 9.9 8.7 0.28 9.4 6.0 1.1 1 0 0 1 1 1 0 Transmembrane protein KxDL PF10241.4 EIW86479.1 - 0.2 11.5 6.1 1.6 8.6 0.9 3.2 2 1 1 3 3 3 0 Uncharacterized conserved protein APG6 PF04111.7 EIW86479.1 - 0.25 10.3 12.9 0.57 9.1 8.9 1.6 1 0 0 1 1 1 0 Autophagy protein Apg6 zf-C4H2 PF10146.4 EIW86479.1 - 0.42 10.6 8.4 1 9.3 5.9 1.8 1 1 0 1 1 1 0 Zinc finger-containing protein FliJ PF02050.11 EIW86479.1 - 0.64 10.0 17.0 0.25 11.3 6.1 3.0 2 1 1 3 3 3 0 Flagellar FliJ protein Fib_alpha PF08702.5 EIW86479.1 - 0.68 10.0 12.4 0.059 13.4 2.7 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.7 EIW86479.1 - 1.9 8.2 8.0 2.2 8.1 2.4 2.7 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EIW86479.1 - 2 8.2 6.6 34 4.2 2.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF342 PF03961.8 EIW86479.1 - 3.4 5.9 9.6 3.9 5.7 6.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF342) Mnd1 PF03962.10 EIW86479.1 - 3.9 7.0 19.1 2.7 7.5 2.5 2.7 1 1 2 3 3 3 0 Mnd1 family NPV_P10 PF05531.7 EIW86479.1 - 4.3 7.6 11.3 7 6.9 2.3 3.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein M_domain PF12938.2 EIW86479.1 - 6.1 6.5 6.7 43 3.8 0.1 2.2 1 1 1 2 2 2 0 M domain of GW182 FliD_N PF02465.13 EIW86480.1 - 0.0019 18.4 0.5 0.0046 17.2 0.0 1.7 2 0 0 2 2 2 1 Flagellar hook-associated protein 2 N-terminus Kinesin PF00225.18 EIW86481.1 - 1.2e-81 274.0 0.1 3e-81 272.7 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Methyltransf_26 PF13659.1 EIW86482.1 - 1.1e-10 41.5 0.0 1.6e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW86482.1 - 5.9e-09 35.5 0.0 8.2e-09 35.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EIW86482.1 - 9.1e-05 22.0 0.0 0.00012 21.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW86482.1 - 0.0076 16.5 0.0 0.022 15.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.5 EIW86482.1 - 0.017 14.6 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF2948 PF11164.3 EIW86482.1 - 0.021 14.4 0.0 0.041 13.4 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2948) DUF1269 PF06897.7 EIW86482.1 - 0.057 13.4 0.1 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) Peptidase_M3_N PF08439.5 EIW86482.1 - 0.065 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Oligopeptidase F Methyltransf_18 PF12847.2 EIW86482.1 - 0.075 13.6 0.0 0.15 12.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 EIW86482.1 - 0.095 13.5 0.0 0.26 12.1 0.0 1.9 2 1 0 2 2 2 0 Methyltransferase domain C2 PF00168.25 EIW86483.1 - 8.4e-79 259.4 7.0 2.1e-15 56.3 0.1 5.5 5 0 0 5 5 5 5 C2 domain zf-Tim10_DDP PF02953.10 EIW86485.1 - 3.9e-20 70.9 1.0 4.7e-20 70.6 0.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EIW86485.1 - 0.05 13.0 1.0 0.064 12.7 0.7 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) LMP PF04778.7 EIW86485.1 - 0.05 13.3 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 LMP repeated region DUF1566 PF07603.6 EIW86485.1 - 0.068 12.9 0.3 0.23 11.2 0.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1566) Acyltransferase PF01553.16 EIW86486.1 - 8.3e-20 70.5 0.0 1.3e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Aa_trans PF01490.13 EIW86487.1 - 1.2e-30 106.3 34.2 1.3e-30 106.2 23.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Abhydrolase_6 PF12697.2 EIW86488.1 - 3.6e-15 56.4 0.4 3.5e-10 40.1 0.0 2.7 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW86488.1 - 0.00071 19.2 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold TMEM154 PF15102.1 EIW86489.1 - 0.004 16.8 7.4 0.004 16.8 5.2 2.6 1 1 1 2 2 2 1 TMEM154 protein family IncA PF04156.9 EIW86489.1 - 2 8.0 4.4 0.27 10.8 0.2 1.6 2 0 0 2 2 2 0 IncA protein PAT1 PF09770.4 EIW86490.1 - 0.65 8.1 11.7 0.71 8.0 8.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Septin PF00735.13 EIW86492.1 - 2.4e-107 358.1 0.0 4e-107 357.4 0.0 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EIW86492.1 - 9.2e-07 28.8 0.0 2.4e-06 27.4 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 EIW86492.1 - 0.0029 16.7 0.0 0.0053 15.8 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EIW86492.1 - 0.0052 17.2 0.3 0.056 13.9 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EIW86492.1 - 0.0058 16.4 5.4 0.24 11.2 0.0 3.0 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 EIW86492.1 - 0.01 15.0 2.8 0.012 14.7 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EIW86492.1 - 0.016 14.6 0.1 0.16 11.3 0.0 2.3 2 1 0 3 3 3 0 Elongation factor Tu GTP binding domain FtsK_SpoIIIE PF01580.13 EIW86492.1 - 0.018 14.5 0.1 0.05 13.0 0.1 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EIW86492.1 - 0.03 15.1 1.5 0.1 13.3 0.1 2.4 1 1 1 2 2 2 0 AAA domain IIGP PF05049.8 EIW86492.1 - 0.11 11.2 0.0 0.23 10.2 0.0 1.5 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Ras PF00071.17 EIW86492.1 - 0.22 10.9 0.6 0.48 9.7 0.0 1.8 2 0 0 2 2 2 0 Ras family Aconitase PF00330.15 EIW86493.1 - 1.1e-160 535.1 0.2 9.5e-160 532.0 0.1 1.9 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EIW86493.1 - 8.8e-35 119.6 0.0 1.6e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Oxysterol_BP PF01237.13 EIW86494.1 - 2.3e-113 378.2 0.0 3.4e-113 377.7 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein PH_8 PF15409.1 EIW86494.1 - 1.7e-16 60.0 0.1 1.2e-15 57.3 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EIW86494.1 - 7.3e-06 26.1 0.0 2.2e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EIW86494.1 - 1.3e-05 25.4 0.8 0.00061 20.0 0.1 2.7 1 1 1 2 2 2 1 Pleckstrin homology domain Pet127 PF08634.5 EIW86494.1 - 0.0082 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 6PGD PF00393.14 EIW86495.1 - 9.1e-132 438.6 0.0 1.1e-131 438.3 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EIW86495.1 - 4.9e-52 176.0 0.0 7e-52 175.5 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EIW86495.1 - 0.0033 17.8 0.1 0.0067 16.8 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EIW86495.1 - 0.0058 16.0 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EIW86495.1 - 0.066 12.3 0.0 0.17 11.0 0.0 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EIW86495.1 - 0.13 11.6 0.1 0.44 9.8 0.0 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Asn_synthase PF00733.16 EIW86496.1 - 2.5e-50 171.3 0.0 3.9e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EIW86496.1 - 1.1e-06 28.3 0.0 3.1e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain QueC PF06508.8 EIW86496.1 - 0.0067 15.7 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC NAD_synthase PF02540.12 EIW86496.1 - 0.0099 14.8 0.0 0.021 13.7 0.0 1.5 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.11 EIW86496.1 - 0.014 13.9 0.0 0.019 13.5 0.0 1.1 1 0 0 1 1 1 0 tRNA methyl transferase ThiI PF02568.9 EIW86496.1 - 0.068 12.6 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) Band_7 PF01145.20 EIW86497.1 - 2e-26 92.9 1.6 3.6e-26 92.1 1.0 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF2522 PF10747.4 EIW86497.1 - 0.046 13.7 0.3 0.076 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2522) MgtE_N PF03448.12 EIW86497.1 - 0.29 11.4 2.2 9.8 6.5 0.0 2.2 2 0 0 2 2 2 0 MgtE intracellular N domain RRM_1 PF00076.17 EIW86498.1 - 6.7e-54 179.4 0.0 5.2e-19 67.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW86498.1 - 1.1e-39 134.2 0.0 1.2e-12 47.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW86498.1 - 7.9e-26 89.6 0.0 1.3e-08 34.4 0.0 3.5 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EIW86498.1 - 0.00047 19.8 0.0 1.4 8.7 0.0 3.3 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 EIW86498.1 - 0.00095 19.0 0.0 1.6 8.7 0.0 2.8 2 1 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) ATG16 PF08614.6 EIW86499.1 - 9.7e-44 149.5 23.2 1.2e-43 149.1 16.1 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF2288 PF10052.4 EIW86499.1 - 0.064 12.9 0.5 0.17 11.6 0.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2288) DUF3574 PF12098.3 EIW86499.1 - 0.23 11.0 6.4 2.9 7.5 0.1 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF3574) DUF310 PF03750.8 EIW86499.1 - 0.26 11.5 3.9 0.48 10.6 2.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF310) DUF2408 PF10303.4 EIW86499.1 - 0.26 11.3 7.2 2.7 8.1 5.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) IncA PF04156.9 EIW86499.1 - 0.35 10.4 23.7 0.97 8.9 4.6 2.7 1 1 1 2 2 2 0 IncA protein GAS PF13851.1 EIW86499.1 - 0.43 9.7 20.8 0.076 12.1 6.2 2.9 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 EIW86499.1 - 0.6 10.4 16.2 0.53 10.6 2.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) M_domain PF12938.2 EIW86499.1 - 0.88 9.3 9.7 0.13 12.0 0.7 2.7 1 1 0 2 2 2 0 M domain of GW182 Fib_alpha PF08702.5 EIW86499.1 - 1.3 9.1 9.8 1 9.4 2.2 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF3584 PF12128.3 EIW86499.1 - 1.3 6.2 17.9 0.29 8.4 9.9 1.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3584) XhlA PF10779.4 EIW86499.1 - 2.1 8.2 6.1 7.2 6.5 2.1 2.8 2 1 0 2 2 2 0 Haemolysin XhlA DUF1664 PF07889.7 EIW86499.1 - 2.2 8.1 5.6 2.3 8.0 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Med10 PF09748.4 EIW86499.1 - 2.8 7.7 6.3 1e+02 2.7 4.3 2.6 1 1 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex FlxA PF14282.1 EIW86499.1 - 3.1 7.7 16.5 1.8 8.5 0.1 3.4 1 1 1 3 3 3 0 FlxA-like protein DUF4094 PF13334.1 EIW86499.1 - 3.2 8.2 8.3 13 6.2 1.6 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4094) Kinesin-relat_1 PF12711.2 EIW86499.1 - 8.7 6.8 13.5 0.38 11.1 1.5 3.4 2 1 1 3 3 3 0 Kinesin motor Ras PF00071.17 EIW86500.1 - 9.3e-58 194.1 0.2 1.1e-57 193.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW86500.1 - 7.3e-19 68.4 0.1 1.6e-18 67.3 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EIW86500.1 - 6.6e-14 51.5 0.0 8.4e-14 51.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW86500.1 - 4.7e-08 32.4 0.1 5.9e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EIW86500.1 - 3.6e-07 30.1 0.0 8.1e-07 29.0 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIW86500.1 - 3.7e-07 29.7 0.0 7.4e-06 25.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EIW86500.1 - 0.00033 20.2 0.4 0.023 14.2 0.1 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EIW86500.1 - 0.0004 20.5 0.0 0.00078 19.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EIW86500.1 - 0.00054 19.4 0.1 0.13 11.7 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.13 EIW86500.1 - 0.00057 18.9 0.3 0.036 13.0 0.0 2.4 2 1 0 2 2 2 1 Septin DUF258 PF03193.11 EIW86500.1 - 0.0013 17.9 0.1 0.0026 16.9 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 cobW PF02492.14 EIW86500.1 - 0.0026 17.2 0.0 0.01 15.2 0.0 1.8 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EIW86500.1 - 0.0043 16.7 0.1 0.04 13.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) NTPase_1 PF03266.10 EIW86500.1 - 0.0051 16.5 0.1 0.011 15.4 0.0 1.6 2 0 0 2 2 2 1 NTPase SRPRB PF09439.5 EIW86500.1 - 0.0051 16.0 0.0 0.0086 15.3 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 EIW86500.1 - 0.0056 16.2 0.3 0.012 15.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EIW86500.1 - 0.0059 16.3 0.3 0.011 15.4 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase MobB PF03205.9 EIW86500.1 - 0.0078 15.9 0.0 0.02 14.5 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EIW86500.1 - 0.014 15.4 0.1 0.021 14.8 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 EIW86500.1 - 0.014 14.8 0.1 0.026 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA-like domain NACHT PF05729.7 EIW86500.1 - 0.047 13.3 0.0 0.088 12.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.13 EIW86500.1 - 0.066 12.4 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_14 PF13173.1 EIW86500.1 - 0.067 13.0 0.1 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EIW86500.1 - 0.099 12.9 0.0 0.4 10.9 0.0 1.9 2 0 0 2 2 2 0 ABC transporter Glucosamine_iso PF01182.15 EIW86501.1 - 1.9e-64 217.0 0.0 2.5e-64 216.6 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase PXA PF02194.10 EIW86502.1 - 1.6e-26 92.9 0.0 1.2e-25 90.1 0.0 2.2 3 0 0 3 3 3 1 PXA domain Aminotran_4 PF01063.14 EIW86504.1 - 7.8e-28 97.4 0.0 1.1e-27 96.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class IV Trypsin_2 PF13365.1 EIW86505.1 - 1.4e-08 34.7 0.0 2.7e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain RRM_6 PF14259.1 EIW86506.1 - 2.6e-08 33.7 0.1 5.3e-06 26.3 0.0 2.5 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.12 EIW86506.1 - 1.9e-07 31.0 0.0 4.5e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 PWI domain zf-CCCH PF00642.19 EIW86506.1 - 0.00043 19.8 4.8 0.00075 19.1 3.4 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PaaX_C PF08223.6 EIW86506.1 - 0.0091 15.7 0.9 0.052 13.2 0.0 2.4 2 0 0 2 2 2 1 PaaX-like protein C-terminal domain RRM_3 PF08777.6 EIW86506.1 - 0.018 14.8 4.6 0.065 13.0 0.1 3.0 3 0 0 3 3 3 0 RNA binding motif RRM_1 PF00076.17 EIW86506.1 - 0.021 14.4 0.4 0.24 11.0 0.0 2.3 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Helicase_C PF00271.26 EIW86508.1 - 6.1e-18 64.4 0.1 1.3e-17 63.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIW86508.1 - 1.2e-17 63.9 0.0 4.2e-17 62.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EIW86508.1 - 3.1e-17 62.9 0.0 8.2e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Y_phosphatase2 PF03162.8 EIW86508.1 - 0.11 11.9 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family G-patch PF01585.18 EIW86509.1 - 3.7e-08 33.0 0.0 7.9e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 G-patch domain zf-C2H2_jaz PF12171.3 EIW86509.1 - 6.1e-05 23.0 6.0 9.8e-05 22.3 4.1 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIW86509.1 - 0.00021 21.3 1.7 0.00034 20.7 1.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type G-patch_2 PF12656.2 EIW86509.1 - 0.0008 19.2 0.0 0.0008 19.2 0.0 2.7 3 0 0 3 3 3 1 DExH-box splicing factor binding site zf-C2H2_2 PF12756.2 EIW86509.1 - 0.0079 16.2 1.8 0.014 15.5 1.2 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) Thioredoxin_2 PF13098.1 EIW86509.1 - 3.3 7.9 5.6 3.7 7.7 2.9 1.8 1 1 1 2 2 2 0 Thioredoxin-like domain HrpA_pilin PF09589.5 EIW86509.1 - 3.6 8.0 8.5 0.5 10.8 2.0 2.2 1 1 1 2 2 2 0 HrpA pilus formation protein Bromodomain PF00439.20 EIW86510.1 - 2.8e-42 142.5 0.1 8.6e-22 76.8 0.0 2.6 2 0 0 2 2 2 2 Bromodomain DUF1664 PF07889.7 EIW86510.1 - 1.1 9.1 3.3 0.62 9.8 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2360 PF10152.4 EIW86510.1 - 1.1 9.5 14.7 1.8 8.8 1.5 3.1 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) Presenilin PF01080.12 EIW86510.1 - 3.5 6.3 5.0 6.2 5.5 3.5 1.4 1 0 0 1 1 1 0 Presenilin CENP-Q PF13094.1 EIW86510.1 - 7 6.6 15.7 0.5 10.3 5.1 2.4 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit WD40 PF00400.27 EIW86511.1 - 3.8e-24 83.6 9.9 2e-07 30.6 0.2 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EIW86511.1 - 0.013 15.2 0.2 15 5.2 0.0 3.1 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIW86511.1 - 0.078 11.0 0.7 0.41 8.7 0.2 2.2 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Frataxin_Cyay PF01491.11 EIW86512.1 - 5.3e-34 116.2 0.0 7.6e-34 115.7 0.0 1.2 1 0 0 1 1 1 1 Frataxin-like domain HK97-gp10_like PF04883.7 EIW86514.1 - 0.023 15.6 0.0 0.051 14.5 0.0 1.5 1 1 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component Rhodanese PF00581.15 EIW86515.1 - 1.8e-21 76.6 0.0 1.1e-11 45.0 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain V-ATPase_C PF03223.10 EIW86516.1 - 3e-116 388.3 2.6 3.3e-116 388.2 1.8 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DUF1202 PF06717.6 EIW86516.1 - 0.0028 17.0 1.6 0.03 13.6 0.1 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1202) KH_1 PF00013.24 EIW86517.1 - 1.6e-37 126.8 0.1 4.4e-09 35.8 0.0 6.7 6 0 0 6 6 6 4 KH domain KH_3 PF13014.1 EIW86517.1 - 8.6e-25 85.9 3.0 7.5e-07 28.6 0.1 6.3 7 0 0 7 7 7 5 KH domain Phage_TAC PF06222.6 EIW86517.1 - 0.05 13.1 0.1 0.095 12.2 0.1 1.4 1 0 0 1 1 1 0 Phage tail assembly chaperone IBR PF01485.16 EIW86518.1 - 8.6e-17 60.7 19.1 1.2e-09 37.8 3.4 4.2 3 1 1 4 4 4 2 IBR domain RWD PF05773.17 EIW86518.1 - 1.2e-13 50.9 0.1 2.2e-13 50.0 0.1 1.4 1 0 0 1 1 1 1 RWD domain zf-RING_2 PF13639.1 EIW86518.1 - 9.9e-05 22.0 9.2 9.9e-05 22.0 6.3 4.8 3 2 2 5 5 5 1 Ring finger domain zf-C3HC4 PF00097.20 EIW86518.1 - 0.00078 19.0 5.6 0.00078 19.0 3.9 4.8 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW86518.1 - 0.0014 18.3 7.6 0.0014 18.3 5.3 4.4 3 1 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIW86518.1 - 0.0069 16.3 10.7 0.0069 16.3 7.4 5.1 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Beta_elim_lyase PF01212.16 EIW86520.1 - 1.9e-67 227.4 0.0 2.4e-67 227.1 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EIW86520.1 - 0.084 11.1 0.0 0.13 10.5 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EIW86521.1 - 8.9e-68 228.5 0.0 1.2e-67 228.1 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase zf-met2 PF12907.2 EIW86522.1 - 3.8e-17 61.9 1.1 5.2e-17 61.5 0.7 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 EIW86522.1 - 1.5e-07 31.9 11.7 1.5e-07 31.9 8.1 1.9 2 0 0 2 2 2 1 4F5 protein family zf-Tim10_DDP PF02953.10 EIW86523.1 - 4.4e-24 83.5 1.3 5e-24 83.3 0.9 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EIW86523.1 - 0.078 12.4 0.8 0.1 12.0 0.5 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) WD40 PF00400.27 EIW86524.1 - 2.6e-15 55.5 17.5 0.0038 17.0 0.1 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Mpv17_PMP22 PF04117.7 EIW86525.1 - 4.7e-24 83.8 0.7 9.1e-24 82.8 0.5 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family PTH2 PF01981.11 EIW86526.1 - 7.9e-36 122.2 0.1 8.8e-36 122.1 0.1 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF3480 PF11979.3 EIW86526.1 - 0.036 12.6 0.1 0.037 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3480) DEAD PF00270.24 EIW86527.1 - 1.7e-44 151.2 0.0 3.6e-44 150.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW86527.1 - 5.7e-23 80.5 0.0 1.1e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EIW86527.1 - 5.4e-20 70.6 0.4 1.2e-19 69.5 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EIW86527.1 - 0.052 13.3 0.1 0.23 11.2 0.0 2.1 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EIW86527.1 - 0.13 12.4 0.5 0.43 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain UPF0121 PF03661.8 EIW86528.1 - 2e-22 79.5 0.2 2.6e-22 79.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) CBS PF00571.23 EIW86529.1 - 9e-36 121.4 12.9 2.9e-09 36.5 0.0 5.5 6 0 0 6 6 6 4 CBS domain PB1 PF00564.19 EIW86529.1 - 5.5e-08 32.3 0.0 1.7e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 PB1 domain KdpC PF02669.10 EIW86529.1 - 0.052 13.2 0.1 0.32 10.6 0.0 2.2 1 1 1 2 2 2 0 K+-transporting ATPase, c chain Glyco_hydro_92 PF07971.7 EIW86530.1 - 1.4e-133 446.2 2.1 1.7e-133 445.9 1.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 MalM PF07148.7 EIW86530.1 - 0.036 13.5 0.0 0.068 12.6 0.0 1.4 1 0 0 1 1 1 0 Maltose operon periplasmic protein precursor (MalM) Sgf11 PF08209.6 EIW86531.1 - 7.5e-15 53.9 1.6 1.7e-14 52.8 1.1 1.6 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.1 EIW86531.1 - 0.02 14.5 1.1 0.037 13.7 0.7 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type MFS_1 PF07690.11 EIW86532.1 - 2.3e-14 52.8 42.6 4.6e-12 45.3 13.4 3.3 2 1 1 3 3 3 3 Major Facilitator Superfamily EVI2A PF05399.6 EIW86533.1 - 0.36 10.0 4.9 0.13 11.4 0.1 2.4 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) SNARE PF05739.14 EIW86534.1 - 7.9e-08 31.8 0.9 1e-07 31.5 0.6 1.1 1 0 0 1 1 1 1 SNARE domain DUF4234 PF14018.1 EIW86534.1 - 0.016 14.9 0.7 0.023 14.4 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4234) Sec20 PF03908.8 EIW86534.1 - 0.088 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Sec20 Peptidase_C48 PF02902.14 EIW86535.1 - 7.9e-41 140.0 0.2 1.7e-40 138.9 0.1 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain Mito_carr PF00153.22 EIW86536.1 - 3.5e-20 71.4 0.0 5.8e-07 29.1 0.0 4.9 4 1 0 4 4 4 3 Mitochondrial carrier protein p450 PF00067.17 EIW86537.1 - 7e-53 179.7 0.0 9.4e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Asp PF00026.18 EIW86538.1 - 5.8e-83 278.7 15.5 6.6e-83 278.5 10.8 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EIW86538.1 - 2.5e-05 23.9 0.1 8e-05 22.2 0.0 2.0 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EIW86538.1 - 0.00019 21.4 8.3 0.00024 21.0 3.8 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal DUF1214 PF06742.6 EIW86538.1 - 0.13 12.6 1.0 5.3 7.5 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1214) Asp_protease_2 PF13650.1 EIW86538.1 - 0.26 11.7 5.4 2.1 8.8 0.9 3.2 2 1 0 2 2 2 0 Aspartyl protease AlaDh_PNT_N PF05222.10 EIW86540.1 - 6.3e-28 97.4 0.0 8.8e-28 96.9 0.0 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EIW86540.1 - 6.5e-13 48.5 0.0 1.2e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain TPR_11 PF13414.1 EIW86541.1 - 2.6e-16 59.0 0.4 2.7e-09 36.5 0.1 2.3 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EIW86541.1 - 4.1e-11 41.9 0.3 2.1e-05 23.9 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EIW86541.1 - 2.6e-08 33.1 0.1 0.00061 19.5 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIW86541.1 - 5.2e-05 22.7 0.0 0.01 15.5 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EIW86541.1 - 0.0006 20.2 0.0 0.0058 17.1 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EIW86541.1 - 0.0085 16.0 0.0 0.6 10.0 0.0 3.0 2 2 0 3 3 3 1 Tetratricopeptide repeat NYD-SP28_assoc PF14775.1 EIW86541.1 - 0.011 15.4 0.1 0.11 12.2 0.0 2.3 1 1 1 2 2 2 0 Sperm tail C-terminal domain TPR_16 PF13432.1 EIW86541.1 - 0.013 16.1 0.0 0.15 12.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.1 EIW86541.1 - 0.021 15.1 0.0 0.077 13.3 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_17 PF13431.1 EIW86541.1 - 0.028 14.6 0.1 0.45 10.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF948 PF06103.6 EIW86541.1 - 0.074 12.9 0.2 16 5.4 0.0 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) MIT PF04212.13 EIW86541.1 - 0.1 12.4 0.4 21 5.0 0.1 3.0 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.1 EIW86541.1 - 0.14 12.0 0.0 0.44 10.4 0.0 1.8 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat DUF3359 PF11839.3 EIW86541.1 - 0.99 9.7 3.7 2 8.7 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3359) PAXNEB PF05625.6 EIW86542.1 - 2.2e-54 184.7 0.0 8.5e-54 182.7 0.0 1.7 1 1 0 1 1 1 1 PAXNEB protein RhoGEF PF00621.15 EIW86543.1 - 2e-47 161.4 0.0 3.5e-47 160.6 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain LRR_4 PF12799.2 EIW86543.1 - 3e-11 42.6 1.8 9.9e-06 25.0 0.1 2.9 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EIW86543.1 - 7.1e-10 38.4 4.4 2.1e-06 27.3 0.7 2.7 1 1 2 3 3 3 3 Leucine rich repeat LRR_1 PF00560.28 EIW86543.1 - 0.0061 16.4 8.2 4.5 7.6 0.3 5.2 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 EIW86543.1 - 0.0069 16.3 1.2 3.3 8.3 0.1 4.1 4 0 0 4 4 4 1 Leucine rich repeat AA_permease PF00324.16 EIW86544.1 - 7.5e-119 397.1 41.6 9.1e-119 396.8 28.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIW86544.1 - 4.2e-34 117.8 45.9 5.8e-34 117.3 31.8 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EIW86545.1 - 7e-123 410.4 40.4 8.4e-123 410.2 28.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EIW86545.1 - 1.6e-31 109.2 45.6 2.1e-31 108.9 31.6 1.1 1 0 0 1 1 1 1 Amino acid permease DUF846 PF05832.7 EIW86547.1 - 1.7e-51 173.6 9.1 2.1e-51 173.3 6.3 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF3792 PF12670.2 EIW86547.1 - 0.0031 17.3 1.0 0.0031 17.3 0.7 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3792) DUF4232 PF14016.1 EIW86547.1 - 0.078 12.6 0.5 0.13 11.9 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) DUF4191 PF13829.1 EIW86547.1 - 0.83 8.7 5.1 4.8 6.2 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) DSPc PF00782.15 EIW86548.1 - 8.5e-21 73.9 0.0 1.1e-18 67.0 0.0 3.0 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EIW86548.1 - 0.012 14.9 0.0 0.019 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase PAT1 PF09770.4 EIW86548.1 - 7.4 4.6 6.4 10 4.2 4.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RVT_3 PF13456.1 EIW86549.1 - 5.7e-07 29.2 0.1 7.2e-07 28.8 0.1 1.1 1 0 0 1 1 1 1 Reverse transcriptase-like RRN9 PF10680.4 EIW86549.1 - 0.0021 17.7 0.4 0.0033 17.1 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor Bombesin PF02044.12 EIW86550.1 - 0.16 11.4 1.5 0.3 10.5 1.1 1.5 1 0 0 1 1 1 0 Bombesin-like peptide FAD_binding_6 PF00970.19 EIW86552.1 - 2.1e-30 104.7 0.0 3.5e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EIW86552.1 - 1.4e-29 102.8 0.0 2.5e-29 102.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EIW86552.1 - 2.7e-06 27.3 0.0 0.0011 18.9 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EIW86552.1 - 0.001 19.0 0.0 0.0023 17.8 0.0 1.6 2 0 0 2 2 2 1 Siderophore-interacting FAD-binding domain O-antigen_lig PF13425.1 EIW86553.1 - 0.017 15.0 0.1 0.025 14.5 0.1 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF1469 PF07332.6 EIW86553.1 - 0.062 13.0 0.2 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) CAP PF00188.21 EIW86554.1 - 2.6e-21 76.4 3.9 3.3e-21 76.0 2.7 1.1 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF2012 PF09430.5 EIW86556.1 - 7.5e-23 80.6 0.0 1.2e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.1 EIW86556.1 - 0.012 15.5 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Fcf1 PF04900.7 EIW86557.1 - 1.6e-27 95.5 0.1 3.4e-27 94.5 0.1 1.5 1 0 0 1 1 1 1 Fcf1 ubiquitin PF00240.18 EIW86558.1 - 9.8e-138 447.7 21.2 5.2e-34 115.4 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.3 EIW86558.1 - 6.7e-78 256.3 20.9 5.8e-19 67.5 0.5 4.0 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EIW86558.1 - 1.6e-24 85.9 9.4 0.00017 21.7 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EIW86558.1 - 2.7e-21 75.9 0.5 0.0016 18.1 0.0 4.0 4 0 0 4 4 4 4 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EIW86558.1 - 3.7e-14 52.5 2.9 0.12 12.3 0.0 4.9 4 4 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EIW86558.1 - 1.2e-13 51.0 1.9 0.15 12.2 0.0 4.2 1 1 3 4 4 4 4 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EIW86558.1 - 1.2e-10 41.2 0.0 1.5 8.8 0.0 4.8 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) FlgD_ig PF13860.1 EIW86558.1 - 2e-07 30.6 4.9 3.5 7.4 0.0 4.3 4 0 0 4 4 4 4 FlgD Ig-like domain Methyltrans_RNA PF04452.9 EIW86558.1 - 8.9e-07 28.2 0.6 1 8.4 0.0 3.3 3 0 0 3 3 3 3 RNA methyltransferase TUG-UBL1 PF11470.3 EIW86558.1 - 3.1e-06 27.0 4.8 6.4 6.7 0.0 4.2 4 0 0 4 4 4 4 GLUT4 regulating protein TUG ACT_4 PF13291.1 EIW86558.1 - 0.00082 19.6 1.2 72 3.8 0.0 4.2 4 0 0 4 4 4 0 ACT domain Big_3_3 PF13750.1 EIW86558.1 - 0.0014 18.0 0.0 50 3.2 0.0 4.0 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) Plexin_cytopl PF08337.7 EIW86558.1 - 0.0043 15.4 13.5 3.9 5.6 0.2 5.6 5 3 0 5 5 5 3 Plexin cytoplasmic RasGAP domain DUF3861 PF12977.2 EIW86558.1 - 0.012 15.6 5.3 65 3.7 0.0 4.3 4 0 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) CTDII PF01556.13 EIW86558.1 - 0.022 14.6 13.9 8.8 6.3 0.2 4.6 1 1 2 4 4 4 0 DnaJ C terminal domain Tash_PEST PF07708.6 EIW86558.1 - 0.027 14.4 29.1 3.5 7.7 1.2 4.3 4 0 0 4 4 4 0 Tash protein PEST motif GABP-alpha PF11620.3 EIW86558.1 - 0.046 13.6 7.0 53 3.9 0.1 4.0 4 0 0 4 4 4 0 GA-binding protein alpha chain FERM_N PF09379.5 EIW86558.1 - 1.4 9.0 12.6 86 3.2 0.1 5.8 4 4 0 4 4 4 0 FERM N-terminal domain CDC48_2 PF02933.12 EIW86558.1 - 1.6 8.4 13.0 40 3.9 0.1 4.1 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 DUF3781 PF12636.2 EIW86558.1 - 2.2 8.2 7.0 1.7e+02 2.2 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF3781) WD40 PF00400.27 EIW86559.1 - 4e-71 232.5 13.1 3.9e-12 45.5 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EIW86559.1 - 2.5e-12 46.9 0.0 2.6e-05 24.0 0.0 3.7 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EIW86559.1 - 2.8e-05 22.4 4.7 0.066 11.3 0.0 4.0 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 EIW86559.1 - 0.00018 20.4 0.2 0.013 14.3 0.0 2.8 1 1 2 3 3 3 1 Coatomer WD associated region IKI3 PF04762.7 EIW86559.1 - 0.046 11.5 0.3 0.29 8.8 0.1 2.1 2 1 0 2 2 2 0 IKI3 family CbiG_N PF11760.3 EIW86559.1 - 0.1 12.2 0.1 22 4.8 0.0 3.2 3 0 0 3 3 3 0 Cobalamin synthesis G N-terminal DUF1513 PF07433.6 EIW86559.1 - 0.11 11.4 0.1 1.5 7.6 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1513) PCI_Csn8 PF10075.4 EIW86560.1 - 6.6e-24 84.3 0.0 1e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EIW86560.1 - 1.1e-19 70.8 0.0 1.4e-19 70.4 0.0 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Aa_trans PF01490.13 EIW86561.1 - 1.1e-53 182.2 18.9 1.4e-53 181.8 13.1 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EIW86561.1 - 4.6e-05 22.4 9.8 4.6e-05 22.4 6.8 1.9 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family DUF2107 PF09880.4 EIW86561.1 - 1.9 8.4 10.5 0.31 10.9 0.2 3.2 2 1 1 3 3 3 0 Predicted membrane protein (DUF2107) WAC_Acf1_DNA_bd PF10537.4 EIW86562.1 - 1.1e-35 121.8 1.2 3.9e-35 120.0 0.8 2.1 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EIW86562.1 - 2e-11 43.4 0.1 4.7e-11 42.2 0.1 1.6 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 EIW86562.1 - 6e-06 25.9 0.6 0.00016 21.5 0.1 2.7 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM1 PF15612.1 EIW86562.1 - 2.4e-05 24.0 0.0 5.7e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 WHIM3 PF15614.1 EIW86562.1 - 4e-05 23.3 0.1 0.00011 21.9 0.1 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 DUF948 PF06103.6 EIW86562.1 - 0.077 12.8 0.2 1.1 9.2 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) GFO_IDH_MocA PF01408.17 EIW86564.1 - 2.4e-10 40.9 0.1 8.4e-10 39.2 0.1 2.0 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EIW86564.1 - 0.0021 17.8 0.1 0.018 14.8 0.1 2.4 1 1 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain HrpF PF06266.7 EIW86564.1 - 0.097 12.8 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 HrpF protein Cyclin_N PF00134.18 EIW86565.1 - 1e-37 128.5 1.1 1.8e-37 127.7 0.4 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EIW86565.1 - 1.8e-09 37.5 0.0 3.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain Complex1_LYR PF05347.10 EIW86568.1 - 1.7e-10 40.4 1.1 2.5e-10 39.9 0.7 1.3 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EIW86568.1 - 9.7e-08 32.1 1.3 1.2e-07 31.7 0.9 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Acyl-CoA_dh_1 PF00441.19 EIW86568.1 - 0.039 14.0 0.6 0.044 13.8 0.4 1.1 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain LSM PF01423.17 EIW86569.1 - 3.1e-17 61.8 0.3 4.2e-17 61.4 0.2 1.2 1 0 0 1 1 1 1 LSM domain Pescadillo_N PF06732.6 EIW86570.1 - 3.4e-119 397.2 0.0 3.4e-119 397.2 0.0 1.5 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 EIW86570.1 - 8.4e-09 35.4 0.0 1.7e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Sec7 PF01369.15 EIW86571.1 - 1.1e-36 126.2 0.0 1.9e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EIW86571.1 - 4.5e-12 46.1 0.1 1.1e-11 44.9 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EIW86571.1 - 6.1e-09 36.0 0.1 1.4e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 PH domain RNA_pol_Rpb8 PF03870.10 EIW86572.1 - 3.4e-41 140.6 0.0 4.3e-41 140.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb8 DUF2404 PF10296.4 EIW86573.1 - 1.4e-05 25.1 0.0 3.7e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) TTL PF03133.10 EIW86574.1 - 3.9e-42 144.1 0.0 5.7e-42 143.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATP-grasp_4 PF13535.1 EIW86574.1 - 0.039 13.7 0.0 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain Pkinase PF00069.20 EIW86575.1 - 7e-68 228.5 0.0 8.9e-68 228.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW86575.1 - 4.9e-26 91.3 0.0 7.3e-26 90.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW86575.1 - 8.8e-06 24.8 0.2 0.00036 19.5 0.1 2.2 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EIW86575.1 - 0.00019 20.8 0.0 0.00029 20.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family SF3b1 PF08920.5 EIW86575.1 - 0.064 13.2 0.9 0.13 12.2 0.6 1.5 1 0 0 1 1 1 0 Splicing factor 3B subunit 1 FAD-oxidase_C PF02913.14 EIW86576.1 - 6.3e-52 176.3 0.0 8.5e-52 175.9 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EIW86576.1 - 2.9e-33 114.2 0.4 4.8e-33 113.5 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Lact-deh-memb PF09330.6 EIW86576.1 - 0.002 17.5 0.0 0.21 10.9 0.0 2.2 2 0 0 2 2 2 2 D-lactate dehydrogenase, membrane binding AMP-binding PF00501.23 EIW86577.1 - 9.4e-71 238.3 0.1 1.1e-70 238.1 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EIW86577.1 - 1e-17 64.8 0.1 3.1e-17 63.2 0.1 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ras PF00071.17 EIW86578.1 - 1.3e-54 183.9 0.0 1.6e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW86578.1 - 4.9e-18 65.7 0.0 7.3e-18 65.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW86578.1 - 8.6e-15 54.4 0.0 5.1e-14 51.8 0.0 1.8 2 0 0 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW86578.1 - 3.7e-08 32.7 0.0 4.1e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIW86578.1 - 8.8e-07 28.5 0.0 1.4e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIW86578.1 - 0.00024 21.0 0.0 0.0025 17.7 0.0 2.0 1 1 0 2 2 2 1 50S ribosome-binding GTPase TCP PF03634.8 EIW86578.1 - 0.11 12.8 0.4 0.17 12.2 0.3 1.2 1 0 0 1 1 1 0 TCP family transcription factor Arrestin_N PF00339.24 EIW86579.1 - 0.08 12.7 0.0 0.28 10.9 0.0 1.8 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain ARID PF01388.16 EIW86580.1 - 3.4e-10 39.6 0.0 9.7e-10 38.1 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF3518 PF12031.3 EIW86580.1 - 0.0076 15.0 0.3 0.066 12.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3518) Cyclin_N PF00134.18 EIW86581.1 - 6.4e-11 41.9 0.0 1.3e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain TFIIB PF00382.14 EIW86581.1 - 0.00092 18.9 0.0 0.014 15.2 0.0 2.5 2 0 0 2 2 2 1 Transcription factor TFIIB repeat AAA_18 PF13238.1 EIW86583.1 - 8.7e-27 93.9 0.1 2e-26 92.7 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EIW86583.1 - 1.4e-16 61.3 0.1 2.4e-16 60.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 EIW86583.1 - 1.4e-06 28.3 0.0 3.2e-06 27.1 0.0 1.6 1 1 0 1 1 1 1 Shikimate kinase AAA PF00004.24 EIW86583.1 - 9.3e-06 25.8 0.0 2.3e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EIW86583.1 - 7.2e-05 22.8 0.1 0.00023 21.1 0.0 1.9 1 1 0 2 2 2 1 AAA domain ADK PF00406.17 EIW86583.1 - 0.00011 22.1 0.1 0.013 15.3 0.0 2.5 2 1 0 2 2 2 1 Adenylate kinase AAA_33 PF13671.1 EIW86583.1 - 0.00057 19.7 0.1 0.0056 16.5 0.0 2.1 1 1 0 2 2 2 1 AAA domain KTI12 PF08433.5 EIW86583.1 - 0.00063 19.0 0.1 0.0025 17.0 0.0 1.8 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_19 PF13245.1 EIW86583.1 - 0.00063 19.4 0.2 0.0013 18.4 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EIW86583.1 - 0.00074 19.6 0.1 0.003 17.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EIW86583.1 - 0.0013 18.1 0.0 0.64 9.3 0.0 2.1 2 0 0 2 2 2 2 Thymidylate kinase Cytidylate_kin2 PF13189.1 EIW86583.1 - 0.0013 18.6 0.0 0.33 10.8 0.0 2.1 1 1 1 2 2 2 2 Cytidylate kinase-like family AAA_14 PF13173.1 EIW86583.1 - 0.011 15.5 0.0 0.036 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EIW86583.1 - 0.014 14.5 0.7 0.54 9.3 0.0 2.1 2 0 0 2 2 2 0 KaiC AAA_16 PF13191.1 EIW86583.1 - 0.014 15.3 0.0 0.039 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 EIW86583.1 - 0.016 15.4 0.1 0.027 14.7 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.7 EIW86583.1 - 0.021 13.9 0.2 0.11 11.5 0.0 1.9 2 0 0 2 2 2 0 Zeta toxin Viral_helicase1 PF01443.13 EIW86583.1 - 0.028 13.9 0.0 0.054 13.0 0.0 1.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.17 EIW86583.1 - 0.028 14.5 0.0 0.069 13.3 0.0 1.7 2 0 0 2 2 2 0 RNA helicase DUF2075 PF09848.4 EIW86583.1 - 0.037 13.0 0.0 0.091 11.7 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) CoaE PF01121.15 EIW86583.1 - 0.038 13.4 0.7 1.4 8.3 0.0 2.3 2 1 0 2 2 2 0 Dephospho-CoA kinase AAA_10 PF12846.2 EIW86583.1 - 0.04 13.3 0.0 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain dNK PF01712.14 EIW86583.1 - 0.041 13.7 0.7 0.06 13.2 0.5 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase RuvB_N PF05496.7 EIW86583.1 - 0.041 12.9 0.0 0.073 12.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ArgK PF03308.11 EIW86583.1 - 0.045 12.5 0.0 0.093 11.4 0.0 1.5 1 0 0 1 1 1 0 ArgK protein NTPase_1 PF03266.10 EIW86583.1 - 0.047 13.4 0.7 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 NTPase Sigma54_activat PF00158.21 EIW86583.1 - 0.053 12.9 0.0 0.087 12.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_30 PF13604.1 EIW86583.1 - 0.11 12.0 0.2 0.39 10.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EIW86583.1 - 0.11 12.5 0.0 0.27 11.2 0.0 1.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 EIW86583.1 - 0.12 11.7 0.0 0.28 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sin_N PF04801.8 EIW86584.1 - 1.8e-19 69.9 0.0 3e-19 69.1 0.0 1.2 1 1 0 1 1 1 1 Sin-like protein conserved region DnaJ PF00226.26 EIW86586.1 - 8.6e-21 73.4 0.9 1.4e-20 72.8 0.6 1.3 1 0 0 1 1 1 1 DnaJ domain Bacteriocin_IIc PF10439.4 EIW86586.1 - 2.3 8.3 11.7 3.2 7.9 3.3 2.3 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_OmpA PF13436.1 EIW86586.1 - 8.1 6.1 10.4 3.7 7.2 2.5 2.4 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 EIW86586.1 - 9 5.9 19.2 10 5.7 5.8 2.8 2 1 0 2 2 2 0 YMGG-like Gly-zipper LIM PF00412.17 EIW86588.1 - 1.9e-05 24.6 0.6 0.0017 18.3 0.1 2.2 2 0 0 2 2 2 1 LIM domain Cytochrome_C554 PF13435.1 EIW86588.1 - 0.087 12.8 2.7 0.088 12.8 1.0 1.7 1 1 0 1 1 1 0 Cytochrome c554 and c-prime Cytochrom_c3_2 PF14537.1 EIW86588.1 - 0.11 12.8 3.6 0.32 11.3 2.5 1.8 1 1 0 1 1 1 0 Cytochrome c3 DUF1720 PF08226.6 EIW86588.1 - 0.41 10.7 4.5 2.1 8.4 3.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF1720) Cytochrome_C7 PF14522.1 EIW86588.1 - 0.65 9.6 5.6 0.34 10.5 1.8 1.9 1 1 1 2 2 2 0 Cytochrome c7 FMN_dh PF01070.13 EIW86589.1 - 5e-109 364.4 0.0 6.3e-109 364.0 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EIW86589.1 - 1.1e-22 79.6 0.1 1e-21 76.5 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NMO PF03060.10 EIW86589.1 - 4.6e-06 26.0 0.0 9e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase Glu_synthase PF01645.12 EIW86589.1 - 1.2e-05 24.4 0.3 3.2e-05 23.0 0.2 1.7 1 1 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EIW86589.1 - 6.1e-05 22.0 0.9 0.00016 20.6 0.2 1.9 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 EIW86589.1 - 0.00046 19.3 0.1 0.22 10.5 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EIW86589.1 - 0.088 12.0 0.1 1 8.6 0.0 2.4 3 0 0 3 3 3 0 Histidine biosynthesis protein CarD_CdnL_TRCF PF02559.11 EIW86589.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 CarD-like/TRCF domain IncA PF04156.9 EIW86590.1 - 0.0078 15.8 1.7 0.013 15.1 1.2 1.3 1 0 0 1 1 1 1 IncA protein Rootletin PF15035.1 EIW86590.1 - 0.019 14.9 1.0 0.04 13.8 0.7 1.4 1 0 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion OmpH PF03938.9 EIW86590.1 - 0.03 14.2 1.2 0.046 13.6 0.9 1.2 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Syntaxin PF00804.20 EIW86590.1 - 0.031 14.4 0.9 0.086 13.0 0.6 1.7 1 0 0 1 1 1 0 Syntaxin RRF PF01765.14 EIW86590.1 - 0.036 13.5 0.3 0.074 12.5 0.2 1.5 1 0 0 1 1 1 0 Ribosome recycling factor DUF948 PF06103.6 EIW86590.1 - 0.061 13.1 1.0 0.13 12.1 0.7 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF812 PF05667.6 EIW86590.1 - 0.072 11.5 1.6 0.11 10.9 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) BLOC1_2 PF10046.4 EIW86590.1 - 0.073 13.2 0.5 0.13 12.3 0.3 1.4 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.2 EIW86590.1 - 0.13 12.0 6.4 0.046 13.5 2.6 1.5 2 0 0 2 2 2 0 Tropomyosin like DUF641 PF04859.7 EIW86590.1 - 0.2 11.4 2.3 0.34 10.6 1.6 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Pkinase PF00069.20 EIW86591.1 - 9.2e-65 218.3 0.0 1.1e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW86591.1 - 5e-27 94.6 0.0 6.8e-27 94.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW86591.1 - 3.6e-05 22.8 0.0 5.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like S_100 PF01023.14 EIW86591.1 - 0.0034 16.6 0.2 0.013 14.7 0.1 2.0 2 0 0 2 2 2 1 S-100/ICaBP type calcium binding domain APH PF01636.18 EIW86591.1 - 0.049 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.17 EIW86591.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.9 EIW86591.1 - 0.12 11.4 0.1 0.21 10.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DKCLD PF08068.7 EIW86592.1 - 7e-29 99.5 0.1 2.6e-28 97.7 0.1 2.0 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EIW86592.1 - 5.4e-24 85.0 0.3 2e-20 73.4 0.2 3.6 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EIW86592.1 - 1e-21 76.4 1.3 2.1e-21 75.4 0.9 1.6 1 0 0 1 1 1 1 PUA domain SR-25 PF10500.4 EIW86592.1 - 0.044 13.2 20.7 0.075 12.4 14.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF680 PF05079.7 EIW86592.1 - 0.41 11.1 1.6 0.89 10.0 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF680) GAGA_bind PF06217.7 EIW86592.1 - 0.89 9.4 10.7 1.4 8.7 7.4 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Ribosomal_60s PF00428.14 EIW86592.1 - 3.3 8.1 14.8 8.8 6.8 10.3 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein SOBP PF15279.1 EIW86592.1 - 6.8 6.9 8.2 11 6.2 5.7 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein RR_TM4-6 PF06459.7 EIW86592.1 - 8 6.2 16.4 13 5.5 11.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ribosomal_L22e PF01776.12 EIW86593.1 - 6.1e-47 158.2 0.6 6.9e-47 158.0 0.4 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family HA2 PF04408.18 EIW86594.1 - 6.4e-18 64.6 0.0 2.3e-17 62.8 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EIW86594.1 - 1.1e-13 50.8 0.1 2.8e-13 49.4 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EIW86594.1 - 2.2e-10 40.3 0.0 6.9e-10 38.7 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EIW86594.1 - 1.1e-06 28.2 0.0 2.1e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EIW86594.1 - 1.3e-06 28.5 0.0 1.2e-05 25.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EIW86594.1 - 0.0051 15.6 0.0 0.015 14.1 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain ABC_tran PF00005.22 EIW86594.1 - 0.0083 16.4 0.0 0.031 14.5 0.0 2.0 1 0 0 1 1 1 1 ABC transporter SNF2_N PF00176.18 EIW86595.1 - 4.6e-67 225.9 0.8 7.6e-67 225.2 0.5 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 EIW86595.1 - 8.2e-48 162.0 18.6 8e-47 158.8 13.7 2.2 2 0 0 2 2 2 1 DNA-binding domain Helicase_C PF00271.26 EIW86595.1 - 6.5e-13 48.3 0.0 1.7e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EIW86595.1 - 6.7e-08 31.6 0.3 8.3e-06 24.8 0.0 2.7 3 0 0 3 3 3 2 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EIW86595.1 - 2.5e-06 27.4 0.1 9.8e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Lyase_1 PF00206.15 EIW86596.1 - 9.4e-118 392.9 0.0 1.2e-117 392.5 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EIW86596.1 - 2.2e-21 75.6 0.0 4.8e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus ADH_N PF08240.7 EIW86596.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain PEX11 PF05648.9 EIW86597.1 - 3.2e-54 183.5 0.6 3.6e-54 183.3 0.4 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Anth_synt_I_N PF04715.8 EIW86597.1 - 0.072 13.1 0.0 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 Anthranilate synthase component I, N terminal region DNA_pol_B PF00136.16 EIW86597.1 - 0.13 10.9 0.0 0.23 10.2 0.0 1.3 1 0 0 1 1 1 0 DNA polymerase family B TPR_4 PF07721.9 EIW86597.1 - 0.16 12.5 0.4 0.16 12.5 0.3 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Cmc1 PF08583.5 EIW86598.1 - 1.4e-08 34.3 0.1 1.5e-08 34.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Radical_SAM PF04055.16 EIW86599.1 - 1.8e-11 44.4 0.0 3.2e-11 43.6 0.0 1.4 1 1 0 1 1 1 1 Radical SAM superfamily Ribosomal_S28e PF01200.13 EIW86600.1 - 6.4e-32 109.1 0.7 7.1e-32 108.9 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Glyco_transf_8 PF01501.15 EIW86601.1 - 7.1e-27 94.3 0.0 1.1e-26 93.6 0.0 1.3 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EIW86601.1 - 9.9e-09 34.9 0.0 1.4e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative PIP49_C PF12260.3 EIW86601.1 - 0.058 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 Peptidase_M22 PF00814.20 EIW86602.1 - 4.8e-85 285.3 0.0 5.6e-85 285.0 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family DUF627 PF04781.7 EIW86602.1 - 0.12 12.0 0.1 0.39 10.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF627) 2-oxoacid_dh PF00198.18 EIW86603.1 - 7e-81 270.8 0.0 9e-81 270.5 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EIW86603.1 - 5.3e-18 64.4 1.9 5.4e-18 64.4 0.3 1.8 2 0 0 2 2 2 1 Biotin-requiring enzyme E3_binding PF02817.12 EIW86603.1 - 5.2e-14 51.6 0.0 1.3e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 e3 binding domain QRPTase_N PF02749.11 EIW86603.1 - 0.085 12.6 0.1 1.1 9.1 0.0 2.3 1 1 1 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain DUF3614 PF12267.3 EIW86603.1 - 0.12 12.6 0.0 0.3 11.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3614) DUF2360 PF10152.4 EIW86603.1 - 1.1 9.5 6.1 1.2 9.3 2.0 2.2 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) EXOSC1 PF10447.4 EIW86604.1 - 3.7e-21 74.8 0.2 6.2e-21 74.1 0.1 1.4 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EIW86604.1 - 0.14 11.4 0.3 0.14 11.4 0.2 1.9 2 1 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region NUDE_C PF04880.8 EIW86605.1 - 1.5e-10 41.7 3.5 1.5e-10 41.7 2.4 6.2 2 2 4 7 7 7 1 NUDE protein, C-terminal conserved region GAS PF13851.1 EIW86605.1 - 0.83 8.8 20.8 1.7 7.8 12.5 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF342 PF03961.8 EIW86605.1 - 1.8 6.8 9.0 1.5 7.1 5.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF342) ADIP PF11559.3 EIW86605.1 - 2.1 8.2 20.4 2.1 8.2 8.6 2.6 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 EIW86605.1 - 6.4 6.5 22.5 0.7 9.6 1.6 2.8 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein APG6 PF04111.7 EIW86605.1 - 8.1 5.3 23.6 1.4 7.9 10.6 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 Es2 PF09751.4 EIW86606.1 - 8.6e-75 252.6 8.7 1.8e-74 251.6 6.1 1.5 1 1 0 1 1 1 1 Nuclear protein Es2 SATase_N PF06426.9 EIW86606.1 - 0.14 12.3 0.5 1.1 9.5 0.0 2.3 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal Nefa_Nip30_N PF10187.4 EIW86607.1 - 3.4e-19 68.9 8.7 4.2e-19 68.6 6.0 1.1 1 0 0 1 1 1 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF914 PF06027.7 EIW86609.1 - 1.2e-09 37.4 8.4 1.2e-09 37.4 5.8 1.9 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EmrE PF13536.1 EIW86609.1 - 1.4e-08 34.9 2.9 1.4e-08 34.9 2.0 3.3 3 1 0 3 3 3 2 Multidrug resistance efflux transporter EamA PF00892.15 EIW86609.1 - 2.1e-07 31.0 5.3 2.1e-07 31.0 3.7 2.9 3 0 0 3 3 3 1 EamA-like transporter family UAA PF08449.6 EIW86609.1 - 7e-06 25.1 13.4 2.6e-05 23.2 9.3 1.7 1 1 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EIW86609.1 - 1.9e-05 23.9 4.1 0.00012 21.2 0.6 2.4 2 1 0 2 2 2 1 Nucleotide-sugar transporter TPT PF03151.11 EIW86609.1 - 3.7e-05 23.4 21.0 0.00014 21.5 1.5 2.4 2 1 0 2 2 2 2 Triose-phosphate Transporter family DUF2583 PF10762.4 EIW86609.1 - 5.7 7.1 5.9 1.9 8.6 0.3 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2583) SLX9 PF15341.1 EIW86610.1 - 1e-19 71.1 1.2 1e-19 71.1 0.9 1.4 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 AMP-binding PF00501.23 EIW86612.1 - 2.4e-22 78.9 0.0 1.3e-21 76.4 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme GH3 PF03321.8 EIW86612.1 - 0.00096 17.7 0.0 0.0015 17.1 0.0 1.2 1 0 0 1 1 1 1 GH3 auxin-responsive promoter Hap4_Hap_bind PF10297.4 EIW86613.1 - 5.6e-09 35.5 3.5 1.7e-08 33.9 2.4 1.9 1 0 0 1 1 1 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 EIW86613.1 - 1.5e-07 31.2 18.2 1e-05 25.3 1.7 2.4 2 0 0 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.10 EIW86613.1 - 0.0051 16.5 23.0 0.33 10.8 6.0 2.5 1 1 1 2 2 2 2 Basic region leucine zipper DUF972 PF06156.8 EIW86613.1 - 0.0091 16.3 7.5 0.021 15.1 5.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF972) HALZ PF02183.13 EIW86613.1 - 0.25 11.0 5.6 0.84 9.4 3.9 1.8 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF2408 PF10303.4 EIW86613.1 - 0.26 11.4 4.3 0.43 10.6 2.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) DUF4191 PF13829.1 EIW86613.1 - 0.32 10.0 2.9 0.5 9.4 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF342 PF03961.8 EIW86613.1 - 0.87 7.9 7.2 1.3 7.3 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF904 PF06005.7 EIW86613.1 - 1 9.6 14.2 1.9 8.8 9.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) TMF_DNA_bd PF12329.3 EIW86613.1 - 5.6 6.8 16.6 13 5.6 11.5 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EIW86613.1 - 7 6.2 11.0 14 5.1 7.6 1.5 1 0 0 1 1 1 0 IncA protein eIF2A PF08662.6 EIW86614.1 - 4.2e-43 147.3 1.1 6.6e-39 133.6 0.0 5.0 3 3 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EIW86614.1 - 5.6e-07 29.1 4.7 0.12 12.3 0.0 6.4 7 0 0 7 7 7 1 WD domain, G-beta repeat RRM_1 PF00076.17 EIW86614.1 - 0.0011 18.4 0.0 0.0027 17.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW86614.1 - 0.035 13.9 0.0 0.079 12.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW86614.1 - 0.062 13.2 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Sugar_tr PF00083.19 EIW86615.1 - 1.1e-41 142.9 28.8 6.2e-40 137.1 19.9 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW86615.1 - 7.8e-17 61.0 43.3 2.4e-09 36.3 15.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EIW86615.1 - 0.0011 18.7 0.5 2.1 8.2 0.1 3.6 3 0 0 3 3 3 2 MFS_1 like family DUF606 PF04657.8 EIW86615.1 - 0.11 12.5 25.4 0.025 14.6 2.0 4.2 2 2 2 4 4 4 0 Protein of unknown function, DUF606 FG-GAP_2 PF14312.1 EIW86615.1 - 7.1 6.7 6.0 9.4 6.3 0.0 3.6 5 0 0 5 5 5 0 FG-GAP repeat SLS PF14611.1 EIW86616.1 - 7e-06 25.6 0.0 1.1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator Spb1_C PF07780.7 EIW86618.1 - 1e-66 224.4 21.8 1e-66 224.4 15.1 2.5 3 0 0 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 EIW86618.1 - 1.9e-52 177.9 0.0 3.6e-52 176.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 EIW86618.1 - 1.5e-48 164.2 1.6 1.5e-48 164.2 1.1 4.0 5 0 0 5 5 5 1 Domain of unknown function (DUF3381) DUF423 PF04241.10 EIW86619.1 - 5.3e-21 74.3 2.1 8.9e-21 73.6 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Bax1-I PF01027.15 EIW86619.1 - 0.29 10.7 7.1 0.31 10.6 4.9 1.0 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF4345 PF14248.1 EIW86619.1 - 0.29 10.6 4.9 0.24 10.8 1.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4345) Ras PF00071.17 EIW86621.1 - 6.7e-54 181.6 0.0 7.6e-54 181.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW86621.1 - 9.4e-17 61.6 0.0 1.3e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW86621.1 - 3.7e-06 26.2 0.0 5.7e-06 25.6 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIW86621.1 - 0.0039 16.6 0.0 0.033 13.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Fungal_trans PF04082.13 EIW86622.1 - 1.5e-11 43.6 0.5 2.8e-11 42.8 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW86622.1 - 0.0064 16.3 7.5 0.015 15.1 5.2 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 EIW86623.1 - 1.1e-53 182.4 0.0 1.4e-53 182.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-CCCH PF00642.19 EIW86624.1 - 6.4e-17 60.8 23.0 4.6e-05 22.9 0.4 4.5 3 1 1 4 4 4 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCHC PF00098.18 EIW86624.1 - 0.00066 19.4 4.2 0.00066 19.4 2.9 2.3 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_3 PF13917.1 EIW86624.1 - 0.0027 17.4 0.1 0.0074 16.0 0.1 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCCH_2 PF14608.1 EIW86624.1 - 0.0028 17.5 26.1 0.071 13.1 0.2 5.4 5 0 0 5 5 5 3 Zinc finger C-x8-C-x5-C-x3-H type F-box PF00646.28 EIW86624.1 - 0.24 11.1 0.9 5.4 6.8 0.1 2.3 2 0 0 2 2 2 0 F-box domain UPF0047 PF01894.12 EIW86625.1 - 1.8e-41 140.6 0.0 2e-41 140.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 Fungal_trans PF04082.13 EIW86626.1 - 1.8e-09 36.8 0.0 3.1e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW86626.1 - 2.8e-06 27.1 11.4 6.6e-06 25.9 7.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RhoGEF PF00621.15 EIW86628.1 - 1.6e-18 67.2 0.0 3e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain Exo_endo_phos PF03372.18 EIW86629.1 - 7.4e-18 65.3 0.0 1.6e-17 64.3 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M16_C PF05193.16 EIW86630.1 - 2.4e-17 63.2 0.1 1.7e-09 37.5 0.0 3.3 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EIW86630.1 - 3.1e-10 39.9 0.0 1.4e-09 37.9 0.0 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Phage_min_cap2 PF06152.6 EIW86630.1 - 0.35 9.7 0.5 0.63 8.9 0.3 1.3 1 0 0 1 1 1 0 Phage minor capsid protein 2 NUFIP1 PF10453.4 EIW86631.1 - 3.7e-16 58.3 0.2 7.4e-16 57.4 0.1 1.5 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DUF1644 PF07800.7 EIW86631.1 - 0.031 14.1 0.1 0.058 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1644) zf-H2C2_5 PF13909.1 EIW86631.1 - 0.2 11.9 0.5 0.35 11.2 0.4 1.4 1 0 0 1 1 1 0 C2H2-type zinc-finger domain DUF605 PF04652.11 EIW86631.1 - 1.3 8.3 10.4 1.7 7.9 7.2 1.2 1 0 0 1 1 1 0 Vta1 like KH_1 PF00013.24 EIW86632.1 - 3.3e-38 129.1 12.7 2.8e-15 55.6 0.2 3.1 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EIW86632.1 - 5.5e-25 86.5 13.8 4.5e-09 35.7 1.5 3.8 4 0 0 4 4 4 3 KH domain KH_4 PF13083.1 EIW86632.1 - 1.5e-11 43.7 0.3 0.00042 19.8 0.0 3.6 3 1 1 4 4 4 3 KH domain KH_2 PF07650.12 EIW86632.1 - 4.2e-08 32.6 5.5 0.1 12.1 0.0 3.6 4 0 0 4 4 4 3 KH domain KH_5 PF13184.1 EIW86632.1 - 0.00018 21.2 4.0 0.43 10.4 0.1 3.5 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 EIW86632.1 - 0.0014 18.0 1.4 0.57 9.6 0.1 2.9 3 0 0 3 3 3 2 dUTPase Ribosomal_L13 PF00572.13 EIW86633.1 - 7.3e-27 93.9 0.0 1.1e-26 93.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L13 SGL PF08450.7 EIW86634.1 - 3.7e-67 226.2 0.0 4.5e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EIW86634.1 - 0.0021 18.0 0.0 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 Arylesterase PD40 PF07676.7 EIW86634.1 - 0.005 16.4 0.3 0.023 14.3 0.1 2.1 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat PP-binding PF00550.20 EIW86635.1 - 7e-13 48.6 0.9 8.9e-13 48.3 0.6 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EIW86635.1 - 2.9e-06 27.2 0.3 3.8e-06 26.8 0.2 1.2 1 0 0 1 1 1 1 Acyl-carrier Ribosomal_L50 PF10501.4 EIW86635.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal subunit 39S DUF1493 PF07377.7 EIW86635.1 - 0.11 12.5 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) Ribosomal_L17 PF01196.14 EIW86636.1 - 1.7e-34 118.2 0.0 2.8e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L17 ADH_N PF08240.7 EIW86637.1 - 4.1e-30 103.7 0.7 9.2e-30 102.6 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW86637.1 - 6.9e-16 57.9 0.1 2.7e-13 49.5 0.0 2.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EIW86637.1 - 0.00015 20.9 0.0 0.00028 20.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_18 PF12847.2 EIW86637.1 - 0.025 15.1 0.0 0.049 14.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FANCL_C PF11793.3 EIW86637.1 - 0.03 14.2 0.7 0.055 13.4 0.5 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain ADH_N_assoc PF13823.1 EIW86637.1 - 0.038 13.6 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated TrkA_N PF02254.13 EIW86637.1 - 0.046 13.7 0.0 0.079 12.9 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain COX4_pro PF03626.9 EIW86640.1 - 0.16 12.1 11.8 0.077 13.1 4.3 2.2 2 0 0 2 2 2 0 Prokaryotic Cytochrome C oxidase subunit IV DUF307 PF03733.8 EIW86640.1 - 0.16 12.4 3.5 12 6.3 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF307) E1_DerP2_DerF2 PF02221.10 EIW86641.1 - 1.1e-24 87.1 0.0 1.4e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EIW86641.1 - 0.00051 20.0 0.0 0.001 19.1 0.0 1.6 1 1 0 1 1 1 1 ML-like domain Ipi1_N PF12333.3 EIW86643.1 - 4.6e-15 55.4 0.0 6.4e-14 51.7 0.0 2.6 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation JAB PF01398.16 EIW86644.1 - 5.9e-16 58.2 0.0 1.1e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Crust_neuro_H PF03858.8 EIW86644.1 - 0.096 13.2 6.1 0.24 11.9 0.4 2.7 2 0 0 2 2 2 0 Crustacean neurohormone H Cation_efflux PF01545.16 EIW86645.1 - 1.4e-77 260.6 0.0 3.1e-77 259.4 0.0 1.5 1 1 0 1 1 1 1 Cation efflux family Cation_efflux PF01545.16 EIW86646.1 - 5.1e-78 262.0 8.5 7.1e-78 261.5 5.9 1.1 1 0 0 1 1 1 1 Cation efflux family DUF805 PF05656.9 EIW86646.1 - 0.0073 16.1 1.8 0.0073 16.1 1.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF805) Med5 PF08689.5 EIW86647.1 - 1.3e-12 46.3 0.9 2.1e-11 42.3 0.5 2.4 1 1 0 1 1 1 1 Mediator complex subunit Med5 Pex14_N PF04695.8 EIW86649.1 - 1.2e-23 83.6 1.1 4.7e-16 59.0 0.1 3.3 2 2 1 3 3 2 2 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1759 PF03564.10 EIW86649.1 - 0.0069 16.2 4.8 0.017 14.9 2.1 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1759) DUF3584 PF12128.3 EIW86649.1 - 0.0074 13.7 11.9 0.01 13.2 8.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Acyl_transf_1 PF00698.16 EIW86649.1 - 0.01 15.2 0.4 0.013 14.8 0.3 1.1 1 0 0 1 1 1 1 Acyl transferase domain DUF342 PF03961.8 EIW86649.1 - 0.013 13.9 2.5 0.019 13.4 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3829 PF12889.2 EIW86649.1 - 0.015 14.4 2.8 0.032 13.4 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3829) DUF2317 PF10079.4 EIW86649.1 - 0.028 13.0 5.6 0.044 12.4 3.9 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Pox_F16 PF04708.7 EIW86649.1 - 0.041 13.1 0.2 0.061 12.5 0.2 1.3 1 0 0 1 1 1 0 Poxvirus F16 protein NPV_P10 PF05531.7 EIW86649.1 - 0.041 14.1 11.1 0.17 12.1 0.9 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF2431 PF10354.4 EIW86649.1 - 0.051 13.5 0.4 0.078 12.9 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2431) ALMT PF11744.3 EIW86649.1 - 0.056 12.0 0.2 0.071 11.7 0.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2450 PF10475.4 EIW86649.1 - 0.064 12.1 4.0 0.091 11.6 2.8 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) Mitofilin PF09731.4 EIW86649.1 - 0.073 11.7 13.5 0.018 13.7 2.6 2.3 1 1 1 2 2 2 0 Mitochondrial inner membrane protein DUF4407 PF14362.1 EIW86649.1 - 0.08 11.8 2.3 0.16 10.9 1.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TROVE PF05731.6 EIW86649.1 - 0.098 11.3 3.9 0.14 10.8 2.7 1.1 1 0 0 1 1 1 0 TROVE domain HSA PF07529.8 EIW86649.1 - 0.12 12.2 4.0 0.19 11.5 2.8 1.3 1 0 0 1 1 1 0 HSA Raptor_N PF14538.1 EIW86649.1 - 0.15 11.9 0.1 0.31 10.8 0.1 1.5 1 0 0 1 1 1 0 Raptor N-terminal CASPase like domain Baculo_PEP_C PF04513.7 EIW86649.1 - 0.18 11.6 4.0 0.33 10.7 2.8 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2959 PF11172.3 EIW86649.1 - 0.2 11.3 5.7 5.3 6.7 4.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2959) DUF2524 PF10732.4 EIW86649.1 - 0.21 11.7 6.4 0.52 10.4 4.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) Prominin PF05478.6 EIW86649.1 - 0.21 9.0 2.7 0.29 8.6 1.9 1.1 1 0 0 1 1 1 0 Prominin Methyltransf_14 PF08484.6 EIW86649.1 - 0.22 11.0 2.6 0.38 10.2 1.8 1.3 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain AAA_13 PF13166.1 EIW86649.1 - 0.24 9.7 7.7 0.33 9.3 5.3 1.1 1 0 0 1 1 1 0 AAA domain Laminin_II PF06009.7 EIW86649.1 - 0.25 11.0 13.1 0.049 13.3 6.6 1.5 2 0 0 2 2 1 0 Laminin Domain II Mt_ATP-synt_D PF05873.7 EIW86649.1 - 0.27 10.8 4.1 0.19 11.3 1.4 1.7 2 1 0 2 2 1 0 ATP synthase D chain, mitochondrial (ATP5H) ING PF12998.2 EIW86649.1 - 0.29 11.4 8.4 0.28 11.4 4.5 1.9 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Noelin-1 PF12308.3 EIW86649.1 - 0.3 10.9 5.6 0.58 9.9 3.9 1.5 1 0 0 1 1 1 0 Neurogenesis glycoprotein Spc7 PF08317.6 EIW86649.1 - 0.37 9.4 9.5 0.56 8.8 6.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TBPIP PF07106.8 EIW86649.1 - 0.37 10.3 11.5 0.56 9.7 8.0 1.3 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Phage_GPO PF05929.6 EIW86649.1 - 0.45 9.7 5.2 0.69 9.1 3.6 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF4071 PF13281.1 EIW86649.1 - 0.58 8.9 4.6 0.8 8.4 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) Peptidase_M75 PF09375.5 EIW86649.1 - 0.62 9.3 5.4 0.95 8.7 0.4 2.2 1 1 1 2 2 2 0 Imelysin Spectrin PF00435.16 EIW86649.1 - 0.69 10.2 9.7 0.38 11.0 4.0 2.4 1 1 1 2 2 2 0 Spectrin repeat DUF1664 PF07889.7 EIW86649.1 - 0.73 9.6 9.1 6.3 6.6 1.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Ribosomal_S13 PF00416.17 EIW86649.1 - 1.2 9.6 5.0 2.1 8.8 3.5 1.5 1 1 0 1 1 1 0 Ribosomal protein S13/S18 Metal_resist PF13801.1 EIW86649.1 - 1.2 9.1 10.8 1.5 8.8 4.8 2.5 1 1 1 2 2 2 0 Heavy-metal resistance Fib_alpha PF08702.5 EIW86649.1 - 1.3 9.1 10.0 0.31 11.1 4.7 1.6 2 0 0 2 2 1 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 EIW86649.1 - 1.4 7.9 13.7 1.9 7.4 9.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 EIW86649.1 - 1.6 7.6 10.8 2.3 7.0 7.5 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 EIW86649.1 - 1.7 8.2 11.3 2.8 7.5 7.8 1.3 1 0 0 1 1 1 0 Mnd1 family IncA PF04156.9 EIW86649.1 - 2.1 7.9 20.1 0.076 12.5 9.8 1.6 2 0 0 2 2 1 0 IncA protein IFT57 PF10498.4 EIW86649.1 - 3.5 6.2 11.9 7.9 5.1 8.3 1.4 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 YkuI_C PF10388.4 EIW86649.1 - 3.7 7.2 7.5 8.9 5.9 0.0 3.0 2 1 1 3 3 3 0 EAL-domain associated signalling protein domain DUF972 PF06156.8 EIW86649.1 - 4.1 7.7 10.4 4.4 7.6 6.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF310 PF03750.8 EIW86649.1 - 4.6 7.4 7.4 1.1 9.4 2.6 1.8 2 1 0 2 2 1 0 Protein of unknown function (DUF310) HisKA_3 PF07730.8 EIW86649.1 - 5.2 7.4 7.3 1.4e+02 2.9 4.8 2.9 1 1 0 1 1 1 0 Histidine kinase Med9 PF07544.8 EIW86649.1 - 6.2 6.6 10.7 1.8 8.3 2.1 2.4 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Baculo_p24 PF05073.7 EIW86649.1 - 6.3 6.3 6.5 23 4.5 4.6 1.8 1 1 0 1 1 1 0 Baculovirus P24 capsid protein DUF2203 PF09969.4 EIW86649.1 - 7.3 6.8 8.2 36 4.6 5.7 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Sas10_Utp3 PF04000.10 EIW86649.1 - 8.3 6.6 7.4 6.2 7.0 1.2 2.6 3 0 0 3 3 2 0 Sas10/Utp3/C1D family V_ATPase_I PF01496.14 EIW86649.1 - 8.5 4.0 6.3 12 3.6 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family COG2 PF06148.6 EIW86649.1 - 10 6.0 12.6 16 5.4 1.8 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 GTP_EFTU PF00009.22 EIW86650.1 - 1.2e-59 200.9 0.4 1.7e-59 200.4 0.3 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EIW86650.1 - 2.1e-27 95.1 0.0 5.5e-27 93.8 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EIW86650.1 - 1.7e-17 63.2 1.8 4.3e-17 61.9 1.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIW86650.1 - 3.7e-05 23.6 0.0 7.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EIW86650.1 - 0.0026 17.3 0.2 0.0061 16.1 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 EIW86650.1 - 0.0036 17.7 0.0 0.0061 17.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein PduV-EutP PF10662.4 EIW86650.1 - 0.012 15.1 0.2 5.6 6.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EIW86650.1 - 0.043 13.2 0.3 0.087 12.2 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DisA_N PF02457.11 EIW86650.1 - 0.067 12.3 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding GCV_H PF01597.14 EIW86651.1 - 4.3e-42 142.6 0.1 4.8e-42 142.5 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.1 EIW86651.1 - 1.7e-05 24.4 0.2 2.4e-05 23.9 0.2 1.3 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain Biotin_lipoyl PF00364.17 EIW86651.1 - 0.00015 21.2 0.2 0.00024 20.6 0.1 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme Peptidase_M23 PF01551.17 EIW86651.1 - 0.032 14.2 0.4 2.7 8.1 0.1 2.2 1 1 1 2 2 2 0 Peptidase family M23 DUF2118 PF09891.4 EIW86651.1 - 0.064 12.9 0.0 0.094 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) ESSS PF10183.4 EIW86652.1 - 7.9e-29 100.1 0.3 9.5e-29 99.8 0.2 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3961 PF13106.1 EIW86652.1 - 0.071 12.6 3.1 0.13 11.8 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) Acetyltransf_1 PF00583.19 EIW86653.1 - 1.5e-16 60.1 0.1 2.2e-16 59.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EIW86653.1 - 1.2e-08 34.5 0.0 3.6e-08 33.0 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.1 EIW86653.1 - 3.2e-08 33.6 0.0 4.4e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIW86653.1 - 7.7e-07 29.1 0.1 1.1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EIW86653.1 - 2.9e-06 27.4 0.0 4.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3490 PF11995.3 EIW86653.1 - 0.0019 17.7 0.7 0.051 13.1 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3490) RIO1 PF01163.17 EIW86654.1 - 9e-48 162.1 0.0 1.7e-47 161.2 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 EIW86654.1 - 2e-33 114.3 0.0 3.5e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EIW86654.1 - 3.3e-10 40.1 0.3 0.00015 21.5 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EIW86654.1 - 1.1e-05 24.5 0.0 9.4e-05 21.5 0.0 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CDC45 PF02724.9 EIW86654.1 - 7.7 4.4 11.0 11 3.9 7.6 1.1 1 0 0 1 1 1 0 CDC45-like protein VID27 PF08553.5 EIW86654.1 - 9.1 4.3 12.2 13 3.8 8.4 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein SMN PF06003.7 EIW86655.1 - 2.6e-07 30.0 2.6 3.6e-07 29.5 1.8 1.2 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) TUDOR PF00567.19 EIW86655.1 - 0.00022 21.0 0.0 0.00051 19.8 0.0 1.6 1 0 0 1 1 1 1 Tudor domain Relaxase PF03432.9 EIW86655.1 - 0.0011 18.4 3.0 0.0016 17.8 2.1 1.2 1 0 0 1 1 1 1 Relaxase/Mobilisation nuclease domain TRF PF08558.5 EIW86655.1 - 0.6 9.4 4.0 0.91 8.8 2.8 1.2 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) FPN1 PF06963.7 EIW86655.1 - 1.1 7.6 2.4 1.4 7.2 1.7 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Pil1 PF13805.1 EIW86656.1 - 6.2e-26 91.1 1.0 1e-25 90.4 0.3 1.6 2 0 0 2 2 2 1 Eisosome component PIL1 GrpE PF01025.14 EIW86656.1 - 5.1 6.6 8.1 0.41 10.1 2.1 1.7 2 0 0 2 2 2 0 GrpE IF4E PF01652.13 EIW86657.1 - 1.9e-47 160.8 0.0 2.5e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E CBS PF00571.23 EIW86658.1 - 2.8e-30 103.8 3.0 5e-12 45.4 0.0 4.4 4 0 0 4 4 4 4 CBS domain SPRY PF00622.23 EIW86659.1 - 2.6e-19 69.5 0.0 3.6e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 SPRY domain tRNA-synt_2 PF00152.15 EIW86660.1 - 2.9e-79 266.2 0.2 5e-79 265.5 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EIW86660.1 - 7e-08 32.2 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EIW86660.1 - 0.0072 15.5 3.0 0.9 8.6 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Peptidase_S49_N PF08496.5 EIW86660.1 - 2.1 8.1 6.3 5.3 6.8 4.4 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Aminotran_1_2 PF00155.16 EIW86661.1 - 6.8e-88 295.0 0.0 7.7e-88 294.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Elong_Iki1 PF10483.4 EIW86662.1 - 1.4e-10 41.0 0.0 3.3e-10 39.8 0.0 1.6 1 1 0 1 1 1 1 Elongator subunit Iki1 KaiC PF06745.8 EIW86662.1 - 0.04 13.0 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 KaiC Acetyltransf_8 PF13523.1 EIW86663.1 - 5.3e-07 29.6 0.0 8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EIW86663.1 - 0.0001 22.3 0.0 0.0002 21.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW86663.1 - 0.00065 19.6 0.0 0.0051 16.8 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EIW86663.1 - 0.0019 18.2 0.0 0.0043 17.1 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EIW86663.1 - 0.093 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DLH PF01738.13 EIW86664.1 - 2.2e-22 79.4 0.0 2.7e-22 79.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EIW86664.1 - 1.1e-05 25.1 0.0 1.5e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 EIW86664.1 - 0.012 15.0 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) GTP_EFTU PF00009.22 EIW86665.1 - 4.1e-56 189.4 0.1 6.2e-56 188.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EIW86665.1 - 1.1e-36 125.0 0.0 2.3e-36 123.9 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EIW86665.1 - 5.1e-16 58.5 1.2 5.1e-16 58.5 0.8 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EIW86665.1 - 0.00062 19.3 0.6 0.0018 17.8 0.4 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EIW86665.1 - 0.0026 17.6 0.3 0.008 16.1 0.2 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Pkinase PF00069.20 EIW86666.1 - 1.1e-43 149.3 0.0 4e-41 140.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW86666.1 - 6.9e-15 54.8 0.0 6.2e-13 48.4 0.0 2.9 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW86666.1 - 0.00013 21.0 0.0 0.00024 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EIW86666.1 - 0.0045 16.7 0.0 0.0072 16.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Ribosomal_L32e PF01655.13 EIW86667.1 - 1.1e-48 163.7 1.8 1.3e-48 163.5 1.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 His_Phos_1 PF00300.17 EIW86668.1 - 1e-21 77.7 0.0 1.5e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) LSM PF01423.17 EIW86669.1 - 4.7e-17 61.2 0.1 6.3e-17 60.8 0.0 1.2 1 0 0 1 1 1 1 LSM domain PHD PF00628.24 EIW86670.1 - 3.1e-09 36.3 8.9 3.1e-09 36.3 6.2 2.3 2 0 0 2 2 2 1 PHD-finger zf-CpG_bind_C PF12269.3 EIW86670.1 - 0.0024 17.3 0.1 0.0024 17.3 0.1 2.2 3 0 0 3 3 3 1 CpG binding protein zinc finger C terminal domain FXR1P_C PF12235.3 EIW86671.1 - 0.00039 20.5 5.1 0.00039 20.5 3.5 4.0 2 1 2 4 4 4 2 Fragile X-related 1 protein C terminal HABP4_PAI-RBP1 PF04774.10 EIW86671.1 - 0.00058 20.3 13.6 0.00058 20.3 9.4 3.8 4 2 1 5 5 5 1 Hyaluronan / mRNA binding family ETC_C1_NDUFA5 PF04716.9 EIW86672.1 - 2e-19 68.8 0.2 3.5e-19 68.0 0.1 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF2524 PF10732.4 EIW86672.1 - 0.038 14.0 0.2 0.057 13.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2524) Ribosomal_L32p PF01783.18 EIW86673.1 - 3.9e-17 62.1 5.5 4.6e-17 61.9 3.8 1.1 1 0 0 1 1 1 1 Ribosomal L32p protein family DZR PF12773.2 EIW86673.1 - 0.016 15.0 0.4 0.02 14.6 0.3 1.3 1 0 0 1 1 1 0 Double zinc ribbon Stc1 PF12898.2 EIW86673.1 - 0.02 14.9 1.2 0.023 14.7 0.8 1.1 1 0 0 1 1 1 0 Stc1 domain GFA PF04828.9 EIW86673.1 - 0.058 13.3 1.6 1.7 8.6 1.1 2.0 1 1 0 1 1 1 0 Glutathione-dependent formaldehyde-activating enzyme GATA PF00320.22 EIW86673.1 - 0.11 11.8 2.3 0.45 9.9 0.3 2.2 2 0 0 2 2 2 0 GATA zinc finger zf-C3HC4 PF00097.20 EIW86673.1 - 0.11 12.1 3.6 3.1 7.5 0.3 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.1 EIW86673.1 - 0.12 12.1 2.5 0.2 11.3 1.7 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 DUF164 PF02591.10 EIW86673.1 - 0.16 11.8 2.8 2.9 7.7 0.2 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain zf-ribbon_3 PF13248.1 EIW86673.1 - 0.88 8.8 5.4 1.7 7.9 3.8 1.5 1 1 0 1 1 1 0 zinc-ribbon domain DUF3133 PF11331.3 EIW86673.1 - 5.7 6.5 6.3 8.2 6.0 0.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3133) Thiolase_N PF00108.18 EIW86674.1 - 6e-71 238.5 0.1 1.1e-70 237.7 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EIW86674.1 - 7.6e-35 119.0 0.6 2.2e-34 117.4 0.2 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EIW86674.1 - 0.0014 18.1 0.1 0.0045 16.4 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain FAE1_CUT1_RppA PF08392.7 EIW86674.1 - 0.14 11.2 0.0 0.37 9.8 0.0 1.7 2 0 0 2 2 2 0 FAE1/Type III polyketide synthase-like protein ACP_syn_III PF08545.5 EIW86674.1 - 0.21 11.2 1.6 8.5 6.1 0.0 2.9 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Amidase PF01425.16 EIW86675.1 - 2.7e-99 333.0 0.0 3.1e-99 332.7 0.0 1.0 1 0 0 1 1 1 1 Amidase DUF4006 PF13179.1 EIW86676.1 - 1.7 8.2 8.0 0.097 12.2 0.9 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF4006) Cytomega_TRL10 PF06084.6 EIW86676.1 - 3.9 7.2 4.3 4.3 7.1 0.4 2.1 1 1 1 2 2 2 0 Cytomegalovirus TRL10 protein Mpp10 PF04006.7 EIW86677.1 - 5.1e-104 348.7 30.2 7.7e-102 341.6 20.9 2.0 1 1 0 1 1 1 1 Mpp10 protein SNARE PF05739.14 EIW86678.1 - 7e-07 28.8 2.1 7e-07 28.8 1.4 3.2 4 1 0 4 4 4 1 SNARE domain V-SNARE_C PF12352.3 EIW86678.1 - 0.0045 17.0 5.6 0.6 10.2 0.2 2.6 2 0 0 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus Ribosomal_S30AE PF02482.14 EIW86678.1 - 0.044 14.2 2.3 0.78 10.2 0.3 2.4 2 0 0 2 2 2 0 Sigma 54 modulation protein / S30EA ribosomal protein DUF1020 PF06255.8 EIW86678.1 - 0.17 11.0 3.3 0.24 10.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1020) Phasin PF05597.6 EIW86678.1 - 0.24 11.1 8.7 0.52 10.0 0.3 2.3 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Sec34 PF04136.10 EIW86678.1 - 0.42 10.3 3.1 0.22 11.2 0.4 1.7 2 0 0 2 2 2 0 Sec34-like family SAD_SRA PF02182.12 EIW86679.1 - 1.5e-43 147.7 0.0 2.1e-43 147.2 0.0 1.2 1 0 0 1 1 1 1 SAD/SRA domain UPF0160 PF03690.8 EIW86682.1 - 1.2e-121 406.0 0.0 2.7e-119 398.2 0.0 2.0 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0160) Ribosomal_L15e PF00827.12 EIW86683.1 - 5.8e-92 306.4 10.9 6.5e-92 306.3 7.6 1.0 1 0 0 1 1 1 1 Ribosomal L15 SurE PF01975.12 EIW86685.1 - 2e-40 138.2 0.0 2.7e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE FliC_SP PF12613.3 EIW86685.1 - 1.9 8.7 6.4 13 6.0 0.1 2.4 2 0 0 2 2 2 0 Flagellin structural protein Helitron_like_N PF14214.1 EIW86686.1 - 9.3e-13 48.3 0.0 1.6e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Helitron helicase-like domain at N-terminus PIF1 PF05970.9 EIW86687.1 - 2.2e-21 76.2 0.6 7.4e-20 71.2 0.4 2.7 1 1 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EIW86687.1 - 4.9e-11 42.5 0.0 1.2e-09 37.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIW86687.1 - 2.3e-05 24.0 0.1 5.8e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain Viral_helicase1 PF01443.13 EIW86687.1 - 0.0067 15.9 0.0 0.47 9.9 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 EIW86687.1 - 0.034 14.2 0.0 0.071 13.2 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_33 PF13671.1 EIW86687.1 - 0.16 11.8 0.9 3.8 7.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain RasGEF PF00617.14 EIW86690.1 - 5.1e-31 107.8 0.0 7.9e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EIW86690.1 - 4.5e-11 42.7 0.0 1e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Miro PF08477.8 EIW86690.1 - 1.1e-05 25.8 0.0 2.7e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EIW86690.1 - 0.00048 19.5 0.0 0.031 13.6 0.0 2.2 2 0 0 2 2 2 1 Ras family Arch_ATPase PF01637.13 EIW86690.1 - 0.067 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Vps53_N PF04100.7 EIW86691.1 - 0.22 10.2 7.3 0.76 8.4 1.8 2.1 2 0 0 2 2 2 0 Vps53-like, N-terminal SNAP PF14938.1 EIW86691.1 - 0.31 10.1 6.2 0.55 9.3 4.3 1.3 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP GAS PF13851.1 EIW86691.1 - 0.6 9.2 11.1 0.49 9.5 4.4 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding MCPsignal PF00015.16 EIW86691.1 - 0.71 9.3 10.3 3.5 7.1 2.8 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain RmuC PF02646.11 EIW86691.1 - 0.83 8.4 8.2 0.048 12.4 1.1 2.0 2 0 0 2 2 2 0 RmuC family DUF1664 PF07889.7 EIW86691.1 - 1.6 8.5 5.4 30 4.4 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) TPR_11 PF13414.1 EIW86691.1 - 3.6 7.2 10.4 3.7 7.2 2.2 3.4 2 1 1 3 3 3 0 TPR repeat PAT1 PF09770.4 EIW86691.1 - 4.8 5.2 17.5 0.046 11.9 6.0 1.9 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 BLOC1_2 PF10046.4 EIW86691.1 - 8.6 6.5 8.6 4.6 7.4 3.0 2.3 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DEAD PF00270.24 EIW86694.1 - 6.3e-47 159.2 0.1 6.5e-46 155.8 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW86694.1 - 1.2e-24 85.9 0.0 2.6e-24 84.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW86694.1 - 3.4e-05 23.7 2.9 0.0091 15.8 0.0 3.2 3 1 0 3 3 3 2 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EIW86694.1 - 0.00072 18.0 0.3 0.0054 15.1 0.1 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1253) DUF1151 PF06625.6 EIW86694.1 - 1.2 8.9 12.7 0.68 9.6 5.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1151) Apc4 PF12896.2 EIW86695.1 - 1.5e-26 93.0 0.1 6.2e-26 91.0 0.0 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 4 bZIP_1 PF00170.16 EIW86696.1 - 0.00021 21.1 7.5 0.00097 19.0 5.2 2.1 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EIW86696.1 - 0.022 14.5 2.5 0.022 14.5 1.8 2.9 2 1 1 3 3 3 0 Basic region leucine zipper TMF_TATA_bd PF12325.3 EIW86696.1 - 0.28 10.9 5.8 0.48 10.1 4.0 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF972 PF06156.8 EIW86696.1 - 0.35 11.2 2.2 0.57 10.5 1.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF972) GPI2 PF06432.6 EIW86697.1 - 1.1e-66 225.1 14.9 4.5e-66 223.0 10.3 1.7 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase MtrD PF04207.7 EIW86697.1 - 0.6 9.4 3.8 8.7 5.6 0.0 2.2 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit D Transposase_21 PF02992.9 EIW86698.1 - 0.0062 15.6 0.1 0.045 12.8 0.0 2.1 2 0 0 2 2 2 1 Transposase family tnp2 TFIID-18kDa PF02269.11 EIW86699.1 - 0.064 13.0 0.1 0.25 11.1 0.0 2.0 2 0 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit Cullin_Nedd8 PF10557.4 EIW86699.1 - 0.16 11.8 0.0 0.56 10.0 0.0 1.8 2 0 0 2 2 2 0 Cullin protein neddylation domain Actin PF00022.14 EIW86701.1 - 8.3e-134 445.9 0.0 9.5e-134 445.7 0.0 1.0 1 0 0 1 1 1 1 Actin Tic20 PF09685.5 EIW86702.1 - 0.00026 20.9 3.0 0.00034 20.5 2.1 1.2 1 0 0 1 1 1 1 Tic20-like protein HEAT PF02985.17 EIW86704.1 - 3.3e-44 145.0 12.6 0.0011 18.8 0.0 13.2 13 0 0 13 13 13 10 HEAT repeat HEAT_2 PF13646.1 EIW86704.1 - 6.7e-32 109.6 16.6 2.5e-08 34.1 0.0 7.0 2 2 5 7 7 7 7 HEAT repeats HEAT_EZ PF13513.1 EIW86704.1 - 6.7e-11 42.3 17.1 0.011 16.1 0.0 9.1 6 4 3 9 9 9 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EIW86704.1 - 8.7e-11 42.0 1.1 0.0063 16.8 0.0 6.8 4 2 5 9 9 9 3 Vacuolar 14 Fab1-binding region Arm PF00514.18 EIW86704.1 - 1.8e-07 30.7 6.3 0.071 12.9 0.0 6.5 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.2 EIW86704.1 - 2e-07 31.0 0.2 1.6e-05 24.8 0.1 3.5 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 EIW86704.1 - 1.1e-05 23.9 7.8 0.0076 14.6 3.9 4.6 2 1 0 2 2 2 2 Adaptin N terminal region HEAT_PBS PF03130.11 EIW86704.1 - 0.00046 20.3 2.0 1.4 9.6 0.2 5.9 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Ecm29 PF13001.2 EIW86704.1 - 0.046 12.1 3.1 1.8 6.9 0.0 3.2 3 1 1 4 4 4 0 Proteasome stabiliser Aldose_epim PF01263.15 EIW86706.1 - 1.2e-29 103.3 0.1 1.4e-29 103.1 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DNA_pol_B PF00136.16 EIW86707.1 - 5.4e-95 318.8 0.0 8.7e-95 318.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EIW86707.1 - 1.6e-24 86.3 0.0 1.4e-12 47.1 0.0 2.3 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EIW86707.1 - 1.1e-08 34.9 0.3 2e-08 34.0 0.2 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta WD40 PF00400.27 EIW86708.1 - 2.7e-07 30.2 11.4 0.0025 17.6 0.0 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat DRAT PF07357.6 EIW86708.1 - 0.13 11.3 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) HSCB_C PF07743.8 EIW86709.1 - 1.8e-12 47.5 6.1 3.3e-12 46.6 4.2 1.4 1 0 0 1 1 1 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EIW86709.1 - 5.4e-08 32.4 0.2 1.2e-07 31.3 0.0 1.7 2 0 0 2 2 2 1 DnaJ domain Phage_lambd_GpG PF06894.6 EIW86709.1 - 0.00063 19.3 1.0 0.0011 18.5 0.5 1.5 1 1 0 1 1 1 1 Bacteriophage lambda minor tail protein (GpG) NifW PF03206.9 EIW86709.1 - 0.072 13.1 0.4 1.2 9.2 0.1 2.2 2 0 0 2 2 2 0 Nitrogen fixation protein NifW LTXXQ PF07813.7 EIW86709.1 - 3.9 7.9 7.2 3.9 8.0 0.8 2.7 2 1 1 3 3 3 0 LTXXQ motif family protein HA2 PF04408.18 EIW86710.1 - 1.7e-17 63.3 0.0 3.8e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Helicase associated domain (HA2) dsrm PF00035.20 EIW86710.1 - 1.8e-13 50.8 0.0 7.6e-10 39.2 0.0 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif Helicase_C PF00271.26 EIW86710.1 - 9.1e-11 41.4 0.0 2e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIW86710.1 - 4.9e-09 35.9 0.1 1e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase OB_NTP_bind PF07717.11 EIW86710.1 - 0.00036 20.3 0.0 0.0008 19.2 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_22 PF13401.1 EIW86710.1 - 0.088 12.9 0.1 0.37 10.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain Adaptin_N PF01602.15 EIW86711.1 - 8e-122 407.2 4.0 8e-122 407.2 2.8 1.7 2 0 0 2 2 2 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EIW86711.1 - 5.3e-39 132.6 0.0 1.2e-38 131.5 0.0 1.6 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EIW86711.1 - 1.2e-19 70.6 0.0 2.7e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Adaptin C-terminal domain C2 PF00168.25 EIW86712.1 - 2.4e-08 33.6 0.0 4.2e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain F-box-like PF12937.2 EIW86713.1 - 1.1e-10 41.0 0.0 1.6e-09 37.3 0.0 2.5 1 1 0 1 1 1 1 F-box-like LRR_6 PF13516.1 EIW86713.1 - 0.12 12.5 0.9 33 4.9 0.0 3.8 2 1 1 3 3 3 0 Leucine Rich repeat ELO PF01151.13 EIW86714.1 - 8.7e-62 208.6 20.7 1.1e-61 208.3 14.3 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family DUF2231 PF09990.4 EIW86714.1 - 0.048 13.9 0.4 0.048 13.9 0.2 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2231) DUF1689 PF07954.6 EIW86714.1 - 1 9.2 5.0 0.64 9.8 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) DUF1162 PF06650.7 EIW86715.1 - 2.7e-58 197.3 0.0 2.7e-54 184.2 0.0 3.9 2 1 1 3 3 3 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EIW86715.1 - 4.5e-32 110.0 0.2 1.7e-31 108.1 0.0 2.2 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EIW86715.1 - 9.9e-07 28.8 0.0 3.9e-06 26.9 0.0 2.0 2 0 0 2 2 2 1 ATG C terminal domain DENN PF02141.16 EIW86716.1 - 9.1e-19 67.8 0.0 1.7e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 DENN (AEX-3) domain CDC45 PF02724.9 EIW86717.1 - 0.14 10.1 0.1 0.17 9.9 0.1 1.0 1 0 0 1 1 1 0 CDC45-like protein GRA6 PF05084.8 EIW86717.1 - 0.29 10.6 3.1 0.41 10.1 2.2 1.3 1 0 0 1 1 1 0 Granule antigen protein (GRA6) Herpes_capsid PF06112.6 EIW86718.1 - 0.37 10.8 7.7 0.55 10.2 5.3 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Raptor_N PF14538.1 EIW86719.1 - 0.00024 20.9 0.0 0.00044 20.1 0.0 1.4 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain Sp100 PF03172.8 EIW86722.1 - 0.051 13.5 0.2 7.4 6.5 0.0 2.6 2 0 0 2 2 2 0 Sp100 domain PRCC PF10253.4 EIW86723.1 - 5.8 7.5 8.8 7.9 7.1 6.1 1.5 1 1 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Aminotran_5 PF00266.14 EIW86726.1 - 0.0038 16.0 0.0 0.0038 16.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Transposase_21 PF02992.9 EIW86727.1 - 2e-13 49.9 0.0 2.5e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Transposase family tnp2 RAG1 PF12940.2 EIW86727.1 - 0.018 13.4 0.0 0.019 13.3 0.0 1.0 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1) DUF2951 PF11166.3 EIW86728.1 - 0.027 14.2 0.6 0.078 12.8 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Mg_trans_NIPA PF05653.9 EIW86729.1 - 3e-21 75.6 8.3 4.2e-11 42.3 0.2 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA AAA_2 PF07724.9 EIW86730.1 - 5.1e-50 169.7 0.0 5.4e-46 156.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 EIW86730.1 - 1.3e-24 86.9 0.0 3.5e-13 49.8 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EIW86730.1 - 6.2e-24 83.7 1.0 1.4e-23 82.5 0.1 2.2 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.15 EIW86730.1 - 4.6e-18 64.8 6.1 1.4e-12 47.2 0.8 4.2 4 0 0 4 4 3 2 Clp amino terminal domain AAA_5 PF07728.9 EIW86730.1 - 2.7e-14 53.0 0.1 7.8e-08 32.1 0.0 3.5 2 2 1 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EIW86730.1 - 8e-12 45.5 7.0 3.2e-05 24.0 0.0 5.4 4 2 0 6 6 6 2 AAA ATPase domain AAA_22 PF13401.1 EIW86730.1 - 4e-11 43.1 0.0 0.0018 18.3 0.0 4.5 2 1 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EIW86730.1 - 7.7e-08 31.9 0.0 7.4e-05 22.2 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.12 EIW86730.1 - 3e-07 30.0 0.0 0.001 18.5 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 EIW86730.1 - 2.2e-06 27.9 0.4 0.0049 17.1 0.0 3.3 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.16 EIW86730.1 - 8.1e-06 25.1 0.0 0.0064 15.6 0.0 2.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EIW86730.1 - 8.7e-06 26.5 6.9 0.21 12.3 3.8 4.0 2 1 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EIW86730.1 - 2.9e-05 23.8 1.2 0.36 10.4 0.2 4.8 4 1 0 4 4 4 1 Archaeal ATPase AAA_33 PF13671.1 EIW86730.1 - 3.3e-05 23.7 0.8 0.13 12.1 0.0 4.0 4 0 0 4 4 4 1 AAA domain Zeta_toxin PF06414.7 EIW86730.1 - 5.7e-05 22.3 0.0 0.02 14.0 0.0 2.9 2 0 0 2 2 2 1 Zeta toxin AAA_24 PF13479.1 EIW86730.1 - 9.2e-05 22.1 0.0 0.13 11.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EIW86730.1 - 9.9e-05 22.0 0.1 0.39 10.5 0.0 3.2 2 0 0 2 2 2 2 Part of AAA domain RNA_helicase PF00910.17 EIW86730.1 - 0.00017 21.7 0.0 1.1 9.4 0.0 2.9 3 0 0 3 3 2 2 RNA helicase TIP49 PF06068.8 EIW86730.1 - 0.00032 19.5 2.7 0.21 10.2 0.0 3.4 3 1 1 4 4 4 2 TIP49 C-terminus NACHT PF05729.7 EIW86730.1 - 0.00059 19.5 0.0 0.11 12.1 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_23 PF13476.1 EIW86730.1 - 0.0034 17.7 3.9 15 5.8 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 EIW86730.1 - 0.0052 16.7 1.8 1.1 9.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain Laminin_II PF06009.7 EIW86730.1 - 0.0064 16.2 1.8 0.018 14.8 1.2 1.8 1 0 0 1 1 1 1 Laminin Domain II PhoH PF02562.11 EIW86730.1 - 0.0089 15.2 0.0 0.74 9.0 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein MobB PF03205.9 EIW86730.1 - 0.02 14.5 0.0 4.3 7.0 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_tran PF00005.22 EIW86730.1 - 0.021 15.1 0.3 5.4 7.3 0.0 3.1 3 0 0 3 3 2 0 ABC transporter DUF258 PF03193.11 EIW86730.1 - 0.026 13.7 0.0 1.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Torsin PF06309.6 EIW86730.1 - 0.028 14.2 0.0 0.37 10.6 0.0 2.4 2 0 0 2 2 2 0 Torsin AAA_29 PF13555.1 EIW86730.1 - 0.029 13.8 0.0 9.6 5.8 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.1 EIW86730.1 - 0.033 13.5 1.6 8.6 5.7 0.0 3.5 3 1 1 4 4 4 0 AAA domain ResIII PF04851.10 EIW86730.1 - 0.038 13.8 0.0 4.1 7.1 0.0 3.2 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_3 PF07726.6 EIW86730.1 - 0.053 13.1 0.0 31 4.1 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EIW86730.1 - 0.07 13.1 0.0 20 5.2 0.0 2.8 2 0 0 2 2 2 0 Sigma-54 interaction domain CbiA PF01656.18 EIW86730.1 - 0.075 12.4 0.0 7.2 5.9 0.0 2.7 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain RepA_C PF04796.7 EIW86730.1 - 0.076 12.6 0.0 0.21 11.1 0.0 1.7 1 0 0 1 1 1 0 Plasmid encoded RepA protein UPF0079 PF02367.12 EIW86730.1 - 0.083 12.5 0.0 19 4.8 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_13 PF13166.1 EIW86730.1 - 0.76 8.1 7.4 0.17 10.2 2.8 1.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EIW86730.1 - 0.94 8.8 5.5 6.8 6.0 0.0 3.8 4 1 1 5 5 4 0 AAA-like domain OmpH PF03938.9 EIW86730.1 - 3.1 7.7 12.1 1.6e+02 2.1 0.0 2.9 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) zf-CHCC PF10276.4 EIW86732.1 - 1.4e-17 63.1 1.3 2.1e-17 62.6 0.9 1.2 1 0 0 1 1 1 1 Zinc-finger domain Pkinase PF00069.20 EIW86733.1 - 6.6e-57 192.6 0.0 1.4e-56 191.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW86733.1 - 2.5e-24 85.7 0.0 4.8e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pribosyltran_N PF13793.1 EIW86734.1 - 2.3e-44 149.8 0.3 6.9e-43 145.0 0.0 2.4 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EIW86734.1 - 3.9e-37 127.7 2.7 2e-32 112.4 0.2 2.6 2 1 1 3 3 3 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EIW86734.1 - 9.8e-12 44.6 1.3 3e-10 39.8 0.5 2.4 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EIW86734.1 - 0.00047 19.4 0.1 0.00078 18.6 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DCP2 PF05026.8 EIW86735.1 - 3.6e-35 119.7 1.5 5.8e-35 119.0 1.1 1.4 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EIW86735.1 - 1.8e-13 50.2 0.0 3.5e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain INCENP_ARK-bind PF03941.10 EIW86736.1 - 7.3e-19 67.3 0.1 1.1e-18 66.7 0.1 1.3 1 0 0 1 1 1 1 Inner centromere protein, ARK binding region Sigma70_r1_2 PF00140.15 EIW86736.1 - 0.0014 18.2 0.1 0.0027 17.3 0.1 1.4 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 DUF3292 PF11696.3 EIW86737.1 - 3.3e-09 35.2 6.5 1.8e-08 32.7 0.4 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF3292) PRT_C PF08372.5 EIW86737.1 - 0.00067 19.1 1.1 0.0015 18.0 0.0 2.1 2 1 1 3 3 3 1 Plant phosphoribosyltransferase C-terminal ACDC PF14733.1 EIW86737.1 - 0.11 12.6 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 AP2-coincident C-terminal Reticulon PF02453.12 EIW86737.1 - 0.13 11.8 4.2 1.3 8.6 0.3 2.4 2 0 0 2 2 2 0 Reticulon DUF639 PF04842.7 EIW86737.1 - 0.7 7.9 4.3 3.4 5.7 0.1 2.8 3 0 0 3 3 3 0 Plant protein of unknown function (DUF639) NUDIX PF00293.23 EIW86738.1 - 3.1e-26 91.6 0.0 4.3e-26 91.1 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain O-FucT PF10250.4 EIW86739.1 - 4.2e-13 49.1 0.0 9.5e-12 44.6 0.0 2.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF3357 PF11837.3 EIW86739.1 - 0.11 12.2 0.1 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DNA_ligase_A_M PF01068.16 EIW86741.1 - 7.9e-63 211.4 0.2 1.3e-62 210.7 0.2 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EIW86741.1 - 1.5e-54 184.5 0.7 2.5e-54 183.7 0.5 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EIW86741.1 - 1.4e-25 89.5 0.0 4.4e-25 87.9 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 EIW86741.1 - 0.0018 17.9 0.1 0.58 9.8 0.0 2.6 2 0 0 2 2 2 2 DNA ligase OB-like domain eIF-3c_N PF05470.7 EIW86741.1 - 0.0076 14.3 0.3 0.038 12.0 0.0 1.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Salp15 PF12115.3 EIW86741.1 - 0.015 15.5 0.0 0.078 13.2 0.0 2.1 2 0 0 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation Ribosomal_S17 PF00366.15 EIW86742.1 - 7.4e-31 106.0 2.8 1.3e-30 105.1 1.9 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 Metallophos PF00149.23 EIW86743.1 - 9.7e-42 142.6 0.1 1.3e-41 142.2 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase EmrE PF13536.1 EIW86744.1 - 6.6e-08 32.7 9.3 6.6e-08 32.7 6.4 2.9 2 1 0 2 2 2 1 Multidrug resistance efflux transporter EamA PF00892.15 EIW86744.1 - 0.074 13.0 40.5 0.023 14.7 6.7 3.2 2 1 1 3 3 3 0 EamA-like transporter family DHFR_1 PF00186.14 EIW86745.1 - 4.7e-31 107.5 0.0 7.5e-31 106.8 0.0 1.3 1 0 0 1 1 1 1 Dihydrofolate reductase RTA1 PF04479.8 EIW86746.1 - 1.3e-36 126.2 1.9 1.7e-36 125.8 1.3 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF4131 PF13567.1 EIW86746.1 - 0.065 12.6 5.8 0.36 10.2 1.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) SGS PF05002.10 EIW86747.1 - 8.5e-30 102.3 1.4 1.3e-29 101.7 1.0 1.3 1 0 0 1 1 1 1 SGS domain CS PF04969.11 EIW86747.1 - 6.6e-09 36.1 0.1 9.6e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 CS domain GST_N_3 PF13417.1 EIW86748.1 - 7.7e-06 26.0 0.0 3.8e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EIW86748.1 - 1.7e-05 24.6 0.1 9e-05 22.2 0.0 2.2 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EIW86748.1 - 0.00052 20.1 0.0 0.0016 18.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EIW86748.1 - 0.00071 19.5 0.0 0.0022 17.9 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EIW86748.1 - 0.0025 17.7 0.0 0.0054 16.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain YopE_N PF09020.5 EIW86748.1 - 0.04 13.9 0.5 0.04 13.9 0.4 1.6 2 0 0 2 2 2 0 YopE, N terminal GST_C_3 PF14497.1 EIW86748.1 - 0.06 13.8 0.1 0.19 12.2 0.1 1.9 2 1 0 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF3407 PF11887.3 EIW86748.1 - 0.12 11.6 0.4 5.4 6.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3407) Galactosyl_T PF01762.16 EIW86749.1 - 4e-09 36.3 0.0 6.6e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 Galactosyltransferase CoA_binding_3 PF13727.1 EIW86750.1 - 0.062 13.1 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 CoA-binding domain Isochorismatase PF00857.15 EIW86751.1 - 8.2e-25 87.7 0.0 1.2e-24 87.2 0.0 1.2 1 0 0 1 1 1 1 Isochorismatase family OppC_N PF12911.2 EIW86752.1 - 0.021 14.1 0.0 0.068 12.5 0.0 1.8 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Ras PF00071.17 EIW86753.1 - 7.2e-54 181.5 0.0 8.6e-54 181.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EIW86753.1 - 7.7e-18 65.1 0.0 1.1e-17 64.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW86753.1 - 1.7e-13 50.1 0.0 2.2e-13 49.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EIW86753.1 - 2.5e-06 26.8 0.0 3.1e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EIW86753.1 - 1.3e-05 24.7 0.0 0.00021 20.7 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIW86753.1 - 7.1e-05 22.7 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EIW86753.1 - 0.00025 20.6 0.0 0.081 12.4 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein NACHT PF05729.7 EIW86753.1 - 0.00097 18.8 0.0 0.0019 17.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain DAP3 PF10236.4 EIW86753.1 - 0.0011 17.9 0.0 0.0018 17.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_16 PF13191.1 EIW86753.1 - 0.0017 18.4 0.7 0.0043 17.0 0.5 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EIW86753.1 - 0.0019 18.3 0.0 0.0038 17.3 0.0 1.6 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.5 EIW86753.1 - 0.0052 16.0 0.0 0.0076 15.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FtsK_SpoIIIE PF01580.13 EIW86753.1 - 0.014 14.9 0.0 0.042 13.3 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family ABC_tran PF00005.22 EIW86753.1 - 0.02 15.2 0.0 0.026 14.8 0.0 1.6 1 1 0 1 1 1 0 ABC transporter Methyltransf_25 PF13649.1 EIW86753.1 - 0.021 15.1 0.0 0.055 13.8 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain UbiD PF01977.11 EIW86753.1 - 0.033 12.6 0.0 0.041 12.3 0.0 1.1 1 0 0 1 1 1 0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Arch_ATPase PF01637.13 EIW86753.1 - 0.037 13.7 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 EIW86753.1 - 0.06 12.8 0.0 0.22 11.0 0.0 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain KaiC PF06745.8 EIW86753.1 - 0.068 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA_14 PF13173.1 EIW86753.1 - 0.11 12.3 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EIW86753.1 - 0.13 11.1 0.0 0.17 10.7 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.14 EIW86753.1 - 0.17 11.3 0.0 0.39 10.1 0.0 1.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Abhydrolase_3 PF07859.8 EIW86754.1 - 6.4e-56 189.2 0.1 9.8e-56 188.6 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EIW86754.1 - 2.4e-05 23.2 0.0 5.2e-05 22.1 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EIW86754.1 - 0.0076 15.4 0.0 2.6 7.2 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Ribonuc_L-PSP PF01042.16 EIW86755.1 - 1.9e-35 121.2 0.0 2.2e-35 121.0 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP RRM_1 PF00076.17 EIW86756.1 - 1.8e-43 146.0 0.3 3.6e-22 77.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW86756.1 - 1.3e-32 111.5 0.1 9.3e-16 57.5 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW86756.1 - 3.3e-26 90.9 0.0 7.4e-11 41.7 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EIW86756.1 - 7e-20 71.0 0.3 1.5e-19 70.0 0.2 1.5 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.6 EIW86756.1 - 2.7e-07 30.3 0.6 0.00015 21.5 0.0 2.6 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.1 EIW86756.1 - 0.009 15.7 0.0 4.8 7.0 0.0 3.0 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif IlvN PF07991.7 EIW86757.1 - 6.7e-48 162.1 0.0 1.1e-47 161.4 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EIW86757.1 - 4.7e-10 39.7 0.1 1e-09 38.6 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EIW86757.1 - 1.9e-06 27.1 0.0 3.1e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EIW86757.1 - 3e-06 27.1 0.0 5.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvC PF01450.14 EIW86757.1 - 3.2e-05 23.8 0.0 6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain NAD_Gly3P_dh_N PF01210.18 EIW86757.1 - 0.0062 16.2 0.3 0.096 12.4 0.2 2.3 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus AdoHcyase_NAD PF00670.16 EIW86757.1 - 0.014 15.1 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain adh_short PF00106.20 EIW86758.1 - 5.6e-25 88.1 0.3 7.7e-25 87.7 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW86758.1 - 5e-24 85.3 0.0 5.9e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW86758.1 - 6.1e-12 45.5 0.1 8.6e-12 45.0 0.1 1.1 1 0 0 1 1 1 1 KR domain Sybindin PF04099.7 EIW86758.1 - 0.019 14.6 0.0 0.024 14.3 0.0 1.2 1 0 0 1 1 1 0 Sybindin-like family Eno-Rase_NADH_b PF12242.3 EIW86758.1 - 0.043 13.6 0.2 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Dak1_2 PF13684.1 EIW86758.1 - 0.063 12.2 0.0 0.086 11.7 0.0 1.1 1 0 0 1 1 1 0 Dihydroxyacetone kinase family Pex16 PF08610.5 EIW86759.1 - 5.6e-74 249.1 0.5 6.8e-74 248.8 0.4 1.1 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) CorA PF01544.13 EIW86760.1 - 3.7e-24 85.2 0.6 3e-12 46.1 0.1 2.8 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein DUF2235 PF09994.4 EIW86761.1 - 4.4e-68 229.6 0.1 6.2e-68 229.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EIW86761.1 - 0.018 14.7 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family SNAP PF14938.1 EIW86763.1 - 1.2e-108 362.6 22.1 1.3e-108 362.4 15.3 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EIW86763.1 - 7.6e-08 32.1 16.8 6.4e-06 26.0 3.1 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EIW86763.1 - 1.5e-05 24.4 12.2 0.042 13.6 0.1 5.5 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 EIW86763.1 - 2.3e-05 23.9 23.4 0.028 14.0 3.9 4.0 4 0 0 4 4 4 3 TPR repeat TPR_6 PF13174.1 EIW86763.1 - 2.9e-05 24.2 9.9 0.44 11.1 0.0 5.4 5 0 0 5 5 4 2 Tetratricopeptide repeat Spatacsin_C PF14649.1 EIW86763.1 - 0.0013 17.6 7.4 0.053 12.4 4.3 2.6 1 1 0 1 1 1 1 Spatacsin C-terminus TPR_2 PF07719.12 EIW86763.1 - 0.006 16.4 19.2 3.3 7.8 0.1 6.0 4 1 1 6 6 6 2 Tetratricopeptide repeat DUF4243 PF14027.1 EIW86763.1 - 0.02 14.3 4.8 0.33 10.3 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4243) TPR_16 PF13432.1 EIW86763.1 - 0.057 14.1 20.3 2.1 9.1 1.3 4.0 1 1 3 4 4 4 0 Tetratricopeptide repeat DUF410 PF04190.8 EIW86763.1 - 0.057 12.9 3.0 0.74 9.3 0.0 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF410) PspA_IM30 PF04012.7 EIW86763.1 - 0.065 12.5 7.9 0.13 11.5 3.3 2.6 1 1 1 2 2 2 0 PspA/IM30 family DUF3962 PF13111.1 EIW86763.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3962) DUF3486 PF11985.3 EIW86763.1 - 0.097 12.7 2.1 0.19 11.7 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3486) Clathrin PF00637.15 EIW86763.1 - 0.11 12.1 2.2 0.39 10.3 0.2 2.8 2 1 2 4 4 4 0 Region in Clathrin and VPS TPR_14 PF13428.1 EIW86763.1 - 0.14 12.8 12.5 8.3 7.3 0.1 5.1 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EIW86763.1 - 0.17 11.7 12.2 0.28 11.0 0.2 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EIW86763.1 - 2.1 8.1 14.5 19 5.0 0.0 5.7 3 1 3 6 6 6 0 Tetratricopeptide repeat PGM_PMM_I PF02878.11 EIW86764.1 - 2.1e-18 66.1 0.1 1.6e-08 34.1 0.0 3.0 2 1 1 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EIW86764.1 - 1.3e-11 44.7 0.0 4.9e-11 42.8 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EIW86764.1 - 2.7e-11 43.3 0.4 3.7e-10 39.6 0.1 2.5 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain ABC_tran PF00005.22 EIW86765.1 - 3.8e-28 98.5 0.0 2.5e-15 56.9 0.0 3.7 3 1 0 3 3 3 2 ABC transporter AAA_21 PF13304.1 EIW86765.1 - 8.5e-10 39.0 0.1 5.1e-05 23.3 0.1 3.1 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EIW86765.1 - 2.6e-05 24.0 2.4 0.22 11.4 0.1 3.1 3 0 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.1 EIW86765.1 - 0.00016 21.1 0.9 0.0077 15.7 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 EIW86765.1 - 0.0023 17.5 0.0 0.0049 16.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EIW86765.1 - 0.0072 16.4 0.1 2 8.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EIW86765.1 - 0.15 12.4 0.2 0.31 11.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EIW86765.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EIW86765.1 - 8.3 6.3 7.8 0.54 10.2 0.1 2.9 3 2 0 3 3 3 0 AAA ATPase domain GATase_4 PF13230.1 EIW86767.1 - 5.8e-22 77.6 0.0 8.7e-22 77.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_2 PF00310.16 EIW86767.1 - 9.2e-11 41.0 0.0 4.2e-08 32.2 0.0 2.4 2 0 0 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EIW86767.1 - 2.9e-10 40.2 0.0 5.8e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain ICE2 PF08426.5 EIW86768.1 - 1.1e-22 80.2 21.5 2.3e-13 49.5 6.4 3.1 1 1 2 3 3 3 3 ICE2 MoaE PF02391.12 EIW86769.1 - 2.7e-30 104.5 0.0 4.2e-30 103.9 0.0 1.3 1 1 0 1 1 1 1 MoaE protein BRCT PF00533.21 EIW86770.1 - 0.091 12.9 0.0 15 5.7 0.0 2.6 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Tim17 PF02466.14 EIW86771.1 - 3.2e-13 49.8 12.7 4.3e-13 49.4 8.8 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.4 EIW86771.1 - 0.00043 20.3 1.9 0.00043 20.3 1.3 3.1 2 1 0 2 2 2 1 Bacteriocin class II with double-glycine leader peptide WD40 PF00400.27 EIW86772.1 - 2.4e-07 30.3 0.4 3.2e-06 26.8 0.0 2.8 3 1 0 3 3 3 1 WD domain, G-beta repeat CS PF04969.11 EIW86773.1 - 3.8e-19 69.0 0.1 6.4e-19 68.2 0.1 1.4 1 0 0 1 1 1 1 CS domain PINIT PF14324.1 EIW86774.1 - 6.4e-36 123.5 0.6 6.4e-36 123.5 0.4 1.7 2 0 0 2 2 2 1 PINIT domain zf-MIZ PF02891.15 EIW86774.1 - 7.7e-17 60.5 7.9 1.3e-16 59.7 5.5 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EIW86774.1 - 8.7e-07 28.3 1.4 1.7e-06 27.4 1.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 EIW86774.1 - 0.014 14.8 0.6 0.056 12.9 0.0 2.2 2 0 0 2 2 2 0 SAP domain Mito_carr PF00153.22 EIW86775.1 - 5.2e-63 208.7 5.6 1.3e-22 79.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein ResIII PF04851.10 EIW86776.1 - 1.7e-20 73.6 0.0 3.3e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EIW86776.1 - 5.5e-17 61.7 0.0 1.3e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW86776.1 - 2.2e-15 56.2 0.0 4.6e-15 55.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EIW86776.1 - 8.8e-08 31.2 0.0 6.4e-07 28.4 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain DUF2075 PF09848.4 EIW86776.1 - 0.00028 20.0 0.0 0.00046 19.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DEAD_2 PF06733.10 EIW86776.1 - 0.0018 17.6 0.0 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 AAA_22 PF13401.1 EIW86776.1 - 0.0076 16.3 0.0 0.024 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EIW86776.1 - 0.011 15.2 0.0 3.2 7.2 0.0 2.6 1 1 1 2 2 2 0 AAA domain cobW PF02492.14 EIW86776.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Helicase_C_2 PF13307.1 EIW86776.1 - 0.027 14.4 0.1 0.17 11.8 0.0 2.3 3 0 0 3 3 3 0 Helicase C-terminal domain Indigoidine_A PF04227.7 EIW86777.1 - 2.4e-119 397.9 0.2 3.6e-119 397.3 0.2 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EIW86777.1 - 2.8e-16 59.5 0.0 9.8e-08 31.4 0.0 2.6 2 1 0 2 2 2 2 pfkB family carbohydrate kinase Kdo PF06293.9 EIW86778.1 - 0.0015 17.6 0.0 0.0033 16.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EIW86778.1 - 0.0019 17.3 0.0 0.0043 16.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ribosomal_S9 PF00380.14 EIW86779.1 - 4.9e-39 133.3 0.7 5.6e-39 133.1 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Ribosomal_L4 PF00573.17 EIW86780.1 - 1.1e-61 207.6 0.2 1.3e-61 207.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family 2-Hacid_dh_C PF02826.14 EIW86781.1 - 1.5e-49 167.5 0.0 3.5e-49 166.3 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EIW86781.1 - 1.7e-32 111.6 0.0 2.3e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EIW86781.1 - 0.011 15.5 0.2 0.047 13.5 0.0 2.0 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Nitro_FeMo-Co PF02579.12 EIW86781.1 - 0.053 13.5 0.1 0.28 11.2 0.0 2.1 1 1 1 2 2 2 0 Dinitrogenase iron-molybdenum cofactor AdoHcyase_NAD PF00670.16 EIW86781.1 - 0.082 12.7 0.0 0.19 11.5 0.0 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Peptidase_M15_4 PF13539.1 EIW86781.1 - 0.16 12.4 0.1 0.49 10.8 0.0 1.8 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase His_biosynth PF00977.16 EIW86782.1 - 8.3e-43 146.2 0.1 1.6e-41 142.0 0.1 2.4 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EIW86782.1 - 4.6e-23 81.6 0.0 1.4e-22 80.1 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EIW86782.1 - 3.1e-07 30.1 0.0 1.1e-06 28.3 0.0 1.8 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain SNO PF01174.14 EIW86782.1 - 0.00039 20.0 0.0 0.0048 16.5 0.0 2.2 2 0 0 2 2 2 1 SNO glutamine amidotransferase family Peptidase_C26 PF07722.8 EIW86782.1 - 0.0067 15.8 0.1 0.041 13.3 0.1 2.0 1 1 0 1 1 1 1 Peptidase C26 Pal1 PF08316.6 EIW86783.1 - 8.9e-16 58.6 0.3 8.9e-16 58.6 0.2 2.7 3 0 0 3 3 3 1 Pal1 cell morphology protein FA_desaturase PF00487.19 EIW86784.1 - 3.3e-33 115.2 29.2 5e-33 114.6 20.2 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EIW86784.1 - 1.8e-10 40.4 0.0 4.2e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AtpR PF12966.2 EIW86784.1 - 0.26 11.4 3.9 6 7.0 0.0 2.9 2 0 0 2 2 2 0 N-ATPase, AtpR subunit Ribosomal_L13e PF01294.13 EIW86785.1 - 1.1e-66 223.7 4.1 1.4e-66 223.3 2.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L13e SKG6 PF08693.5 EIW86786.1 - 0.041 13.1 1.0 0.1 11.9 0.7 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain ImpE PF07024.8 EIW86786.1 - 0.062 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 ImpE protein Rick_17kDa_Anti PF05433.10 EIW86786.1 - 0.085 12.5 6.5 0.27 10.9 4.5 1.8 1 0 0 1 1 1 0 Glycine zipper 2TM domain Amnionless PF14828.1 EIW86786.1 - 0.2 10.0 0.0 0.28 9.6 0.0 1.1 1 0 0 1 1 1 0 Amnionless DUF2613 PF11021.3 EIW86786.1 - 4.9 6.9 9.0 14 5.4 5.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2613) WD40 PF00400.27 EIW86788.1 - 1e-57 190.0 15.5 9.5e-11 41.1 0.5 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EIW86788.1 - 8.6e-33 113.4 0.0 2.9e-32 111.7 0.0 1.8 2 0 0 2 2 2 1 WD40 associated region in TFIID subunit LisH PF08513.6 EIW86788.1 - 0.015 15.0 0.1 1.8 8.4 0.0 2.6 2 0 0 2 2 2 0 LisH Nup160 PF11715.3 EIW86788.1 - 0.021 12.9 8.2 1.2 7.1 0.1 4.1 1 1 2 4 4 4 0 Nucleoporin Nup120/160 NAD_binding_6 PF08030.7 EIW86789.1 - 5.2e-24 84.9 0.0 1.1e-23 83.8 0.0 1.5 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EIW86789.1 - 2.7e-21 75.3 0.0 6.5e-21 74.1 0.0 1.7 1 1 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EIW86789.1 - 6.3e-16 58.6 12.9 6.3e-16 58.6 8.9 2.0 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EIW86789.1 - 0.0024 18.4 0.0 0.29 11.7 0.0 2.4 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EIW86789.1 - 0.0031 17.6 0.0 0.0097 16.0 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Nucleoporin_C PF03177.9 EIW86790.1 - 9.2e-83 278.7 0.0 1.2e-82 278.3 0.0 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EIW86790.1 - 8.4e-61 205.9 1.3 1.9e-60 204.8 0.9 1.5 1 0 0 1 1 1 1 Nup133 N terminal like RINGv PF12906.2 EIW86791.1 - 2.2e-13 50.0 3.3 3.2e-13 49.4 2.3 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EIW86791.1 - 0.0014 18.3 5.4 0.0025 17.5 3.8 1.4 1 0 0 1 1 1 1 Ring finger domain PHD PF00628.24 EIW86791.1 - 0.023 14.3 3.1 0.037 13.7 2.2 1.3 1 0 0 1 1 1 0 PHD-finger zinc_ribbon_4 PF13717.1 EIW86791.1 - 0.097 12.3 0.3 0.23 11.1 0.2 1.6 1 0 0 1 1 1 0 zinc-ribbon domain FANCL_C PF11793.3 EIW86791.1 - 0.45 10.5 3.0 0.87 9.5 2.1 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EIW86791.1 - 0.89 9.1 4.5 2 8.0 3.1 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain RNase_T PF00929.19 EIW86792.1 - 1.6e-10 41.4 0.0 2.3e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Exonuclease PPR_2 PF13041.1 EIW86793.1 - 0.0028 17.6 0.0 0.098 12.6 0.0 3.0 4 0 0 4 4 4 1 PPR repeat family PPR PF01535.15 EIW86793.1 - 0.097 12.6 0.0 12 6.1 0.0 3.5 3 0 0 3 3 3 0 PPR repeat Rhomboid PF01694.17 EIW86795.1 - 1.4e-28 99.7 13.7 1.4e-28 99.7 9.5 1.9 3 0 0 3 3 3 1 Rhomboid family Herpes_UL43 PF05072.8 EIW86795.1 - 0.0015 17.3 0.7 0.029 13.1 0.2 2.3 2 0 0 2 2 2 1 Herpesvirus UL43 protein P12 PF12669.2 EIW86795.1 - 0.013 15.6 0.1 0.013 15.6 0.1 2.4 2 0 0 2 2 2 0 Virus attachment protein p12 family DUF3353 PF11833.3 EIW86795.1 - 0.047 13.1 0.2 0.14 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) Acyl-CoA_dh_1 PF00441.19 EIW86796.1 - 8.4e-30 103.8 0.1 1.6e-29 102.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 EIW86796.1 - 4.9e-17 61.4 0.0 1.3e-16 60.1 0.0 1.8 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 EIW86796.1 - 1.7e-13 49.8 0.8 1.8e-12 46.5 0.6 2.3 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EIW86796.1 - 3.4e-13 50.1 0.0 6.3e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EIW86796.1 - 0.00012 22.3 0.1 0.00024 21.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain gp37_C PF12604.3 EIW86796.1 - 0.14 11.9 0.1 0.32 10.7 0.0 1.6 2 0 0 2 2 2 0 Tail fiber protein gp37 C terminal SnoaL PF07366.7 EIW86797.1 - 0.0003 20.3 0.0 0.00048 19.7 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EIW86797.1 - 0.005 17.2 0.1 0.0092 16.3 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain DIL PF01843.14 EIW86798.1 - 4.6e-22 77.8 2.5 5.5e-22 77.6 0.9 1.8 2 0 0 2 2 2 1 DIL domain Ank PF00023.25 EIW86798.1 - 5e-09 35.5 1.1 0.0004 20.0 0.1 3.9 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EIW86798.1 - 8.3e-09 35.7 0.0 2.7e-06 27.7 0.0 3.5 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EIW86798.1 - 3.2e-08 33.8 0.0 2.2e-07 31.1 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIW86798.1 - 3.8e-07 30.1 0.6 0.00029 21.0 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIW86798.1 - 0.0003 20.7 5.4 0.0039 17.2 0.0 4.8 6 0 0 6 6 6 1 Ankyrin repeat Rrp15p PF07890.7 EIW86799.1 - 1.2e-18 67.4 10.8 3.3e-18 65.9 7.5 1.9 1 1 0 1 1 1 1 Rrp15p CLTH PF10607.4 EIW86800.1 - 4.2e-35 120.5 0.0 5.7e-35 120.1 0.0 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EIW86800.1 - 9.6e-11 41.0 0.2 2e-10 40.0 0.1 1.6 1 0 0 1 1 1 1 LisH UPF0270 PF06794.7 EIW86800.1 - 0.053 13.2 0.1 0.26 11.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) TINF2_N PF14973.1 EIW86800.1 - 0.089 12.9 0.2 0.2 11.7 0.0 1.6 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus GntR PF00392.16 EIW86800.1 - 0.36 10.3 2.0 1.3 8.4 0.1 2.5 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family Pkinase PF00069.20 EIW86801.1 - 2.7e-68 229.9 0.0 3.4e-68 229.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW86801.1 - 2.1e-46 158.0 0.0 4.4e-46 157.0 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW86801.1 - 3.2e-08 32.8 0.0 2.3e-05 23.5 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EIW86801.1 - 0.0037 16.3 0.0 0.0068 15.4 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EIW86801.1 - 0.0062 15.8 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 EIW86801.1 - 0.078 12.7 0.0 0.23 11.1 0.0 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EIW86801.1 - 0.15 10.8 0.0 0.24 10.1 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 IQ PF00612.22 EIW86802.1 - 0.0072 15.8 0.3 0.018 14.6 0.2 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif SASRP1 PF15160.1 EIW86803.1 - 0.073 12.2 0.0 0.09 12.0 0.0 1.1 1 0 0 1 1 1 0 Spermatogenesis-associated serine-rich protein 1 DUF866 PF05907.8 EIW86804.1 - 1.5e-46 157.8 0.0 1.6e-46 157.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Cytochrome_C7 PF14522.1 EIW86804.1 - 0.0034 16.9 0.2 0.0054 16.3 0.2 1.3 1 0 0 1 1 1 1 Cytochrome c7 DUF3716 PF12511.3 EIW86804.1 - 0.12 11.9 1.9 0.25 10.9 1.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Terminase_GpA PF05876.7 EIW86804.1 - 0.13 10.6 0.6 0.21 9.9 0.4 1.4 1 1 0 1 1 1 0 Phage terminase large subunit (GpA) Thioredoxin_2 PF13098.1 EIW86804.1 - 0.19 11.8 0.5 0.36 11.0 0.4 1.7 1 1 0 1 1 1 0 Thioredoxin-like domain MRP-S28 PF10213.4 EIW86805.1 - 2.5e-25 88.9 0.0 3.3e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit protein CN_hydrolase PF00795.17 EIW86806.1 - 1.9e-29 102.3 0.0 2.5e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Septin PF00735.13 EIW86807.1 - 2.3e-124 414.0 0.1 2.3e-124 414.0 0.1 1.6 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EIW86807.1 - 5.1e-07 29.6 0.0 1.1e-06 28.5 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EIW86807.1 - 1.1e-05 24.9 0.3 0.00069 19.1 0.0 3.0 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EIW86807.1 - 1.2e-05 24.5 0.1 4.4e-05 22.7 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EIW86807.1 - 0.00014 21.0 0.3 0.00066 18.8 0.0 2.4 2 0 0 2 2 2 1 AIG1 family Dynamin_N PF00350.18 EIW86807.1 - 0.00036 20.3 2.5 0.3 10.8 0.0 3.2 2 1 0 3 3 3 2 Dynamin family Ras PF00071.17 EIW86807.1 - 0.00091 18.6 0.2 0.0071 15.7 0.0 2.5 3 1 0 3 3 3 1 Ras family AAA_22 PF13401.1 EIW86807.1 - 0.001 19.2 0.1 0.019 15.0 0.0 2.6 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EIW86807.1 - 0.0036 17.3 0.6 0.031 14.2 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain GrpE PF01025.14 EIW86807.1 - 0.0051 16.3 4.6 0.015 14.8 3.2 1.9 1 0 0 1 1 1 1 GrpE AAA_10 PF12846.2 EIW86807.1 - 0.0065 15.9 0.3 0.026 13.9 0.0 2.0 2 0 0 2 2 2 1 AAA-like domain Miro PF08477.8 EIW86807.1 - 0.01 16.3 0.0 0.13 12.7 0.0 2.7 2 1 0 3 3 2 1 Miro-like protein AAA_29 PF13555.1 EIW86807.1 - 0.018 14.5 0.0 0.034 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EIW86807.1 - 0.027 14.7 9.7 0.023 15.0 0.9 2.8 1 1 1 2 2 2 0 ABC transporter AAA_24 PF13479.1 EIW86807.1 - 0.029 13.9 0.6 0.14 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Exonuc_VII_L PF02601.10 EIW86807.1 - 0.037 13.2 3.8 0.084 12.0 2.6 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Gtr1_RagA PF04670.7 EIW86807.1 - 0.049 12.7 0.1 0.17 11.0 0.0 2.0 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Strep_SA_rep PF06696.6 EIW86807.1 - 0.055 13.2 1.0 0.12 12.1 0.3 2.0 1 1 0 1 1 1 0 Streptococcal surface antigen repeat MobB PF03205.9 EIW86807.1 - 0.062 13.0 0.1 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EIW86807.1 - 0.082 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain PduV-EutP PF10662.4 EIW86807.1 - 0.11 11.9 0.0 3.1 7.2 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 EIW86807.1 - 0.12 11.8 2.6 6 6.3 0.0 3.2 3 1 0 3 3 2 0 Conserved hypothetical ATP binding protein RNA_helicase PF00910.17 EIW86807.1 - 0.12 12.5 0.2 0.87 9.7 0.0 2.4 2 1 1 3 3 3 0 RNA helicase IIGP PF05049.8 EIW86807.1 - 0.31 9.8 0.1 0.31 9.8 0.0 2.7 3 1 0 4 4 4 0 Interferon-inducible GTPase (IIGP) IncA PF04156.9 EIW86807.1 - 1 8.9 6.3 1.8 8.1 4.3 1.4 1 0 0 1 1 1 0 IncA protein DUF87 PF01935.12 EIW86807.1 - 1.5 8.6 6.3 4.1 7.1 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 Xpo1 PF08389.7 EIW86808.1 - 8.1e-24 84.2 0.1 1.6e-22 80.0 0.0 3.1 4 0 0 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 EIW86808.1 - 6.3e-06 26.0 0.0 3.4e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 Importin-beta N-terminal domain CoA_binding PF02629.14 EIW86809.1 - 3.3e-29 101.2 0.9 8.3e-29 99.9 0.1 2.0 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EIW86809.1 - 4.1e-24 84.9 0.1 6.4e-24 84.2 0.0 1.3 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EIW86809.1 - 7.8e-10 38.4 0.1 2.2e-09 37.0 0.0 1.8 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EIW86809.1 - 4.1e-06 26.9 0.0 2.3e-05 24.5 0.0 2.2 3 0 0 3 3 3 1 CoA binding domain GFO_IDH_MocA PF01408.17 EIW86809.1 - 0.00027 21.4 0.0 0.00087 19.8 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold ACBP PF00887.14 EIW86810.1 - 9.5e-16 57.2 0.0 1.7e-15 56.4 0.0 1.4 1 1 0 1 1 1 1 Acyl CoA binding protein Ank_5 PF13857.1 EIW86810.1 - 2.9e-14 52.7 0.3 4.8e-14 52.0 0.2 1.3 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EIW86810.1 - 3.3e-11 42.3 0.0 4.6e-09 35.6 0.1 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 EIW86810.1 - 6.7e-11 42.3 0.0 1.1e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EIW86810.1 - 1.9e-10 40.9 0.1 2e-07 31.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIW86810.1 - 2.3e-07 30.4 0.0 7.1e-07 28.8 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ribosomal_S16 PF00886.14 EIW86811.1 - 4.2e-19 68.0 0.0 6.8e-19 67.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S16 LSM PF01423.17 EIW86812.1 - 5.8e-20 70.6 0.1 6.5e-20 70.4 0.1 1.0 1 0 0 1 1 1 1 LSM domain Arm PF00514.18 EIW86813.1 - 2.7e-90 293.4 12.9 7.8e-13 47.7 0.0 8.2 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EIW86813.1 - 4.3e-22 78.2 0.8 5.1e-07 29.8 0.0 5.1 1 1 6 7 7 7 4 HEAT repeats HEAT_EZ PF13513.1 EIW86813.1 - 4.5e-22 77.9 3.2 6.3e-08 32.8 0.0 5.5 4 1 2 6 6 6 3 HEAT-like repeat IBB PF01749.15 EIW86813.1 - 4.5e-19 68.4 0.4 7.5e-19 67.7 0.3 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 EIW86813.1 - 1.8e-15 55.5 0.6 9.3e-05 22.2 0.0 6.2 6 0 0 6 6 6 2 HEAT repeat Arm_2 PF04826.8 EIW86813.1 - 1.9e-07 30.4 0.0 0.13 11.2 0.0 4.0 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 EIW86813.1 - 6.6e-06 24.7 0.0 0.0012 17.2 0.0 2.9 1 1 2 3 3 3 1 Adaptin N terminal region RICTOR_V PF14668.1 EIW86813.1 - 0.00017 21.4 2.8 0.34 10.8 0.0 4.4 3 2 1 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 V-ATPase_H_C PF11698.3 EIW86813.1 - 0.0052 16.6 0.2 1.7 8.5 0.0 3.8 2 2 2 5 5 5 2 V-ATPase subunit H HEAT_PBS PF03130.11 EIW86813.1 - 0.0063 16.8 2.3 0.57 10.8 0.0 4.3 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Mo25 PF08569.6 EIW86813.1 - 0.11 11.5 0.0 0.29 10.1 0.0 1.7 2 0 0 2 2 2 0 Mo25-like PC_rep PF01851.17 EIW86814.1 - 3.4e-33 112.0 25.5 1.2e-08 34.7 0.0 9.9 10 0 0 10 10 10 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EIW86814.1 - 1.4e-19 70.1 1.3 2.1e-10 40.7 0.0 4.7 2 1 4 6 6 6 4 HEAT repeats HEAT PF02985.17 EIW86814.1 - 1.8e-07 30.6 0.2 1.9 8.7 0.1 5.0 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.1 EIW86814.1 - 1.3e-06 28.7 0.9 0.01 16.3 0.0 4.8 4 0 0 4 4 4 2 HEAT-like repeat COX6A PF02046.10 EIW86815.1 - 4.1e-27 94.4 0.1 4.3e-27 94.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIa DUF3432 PF11914.3 EIW86816.1 - 2.9 7.9 11.4 0.17 11.8 3.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3432) Ribul_P_3_epim PF00834.14 EIW86817.1 - 1.4e-64 216.8 0.0 1.7e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PG_binding_3 PF09374.5 EIW86817.1 - 0.036 14.0 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 Predicted Peptidoglycan domain Gly_transf_sug PF04488.10 EIW86818.1 - 2e-05 24.8 0.0 5.2e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EIW86818.1 - 0.03 13.5 0.3 0.046 12.8 0.2 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Glyco_transf_8 PF01501.15 EIW86818.1 - 0.064 12.5 0.0 0.54 9.5 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 8 Gly_transf_sug PF04488.10 EIW86819.1 - 0.0001 22.6 0.0 0.00023 21.4 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EIW86819.1 - 0.0042 16.3 0.3 0.0068 15.5 0.2 1.2 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein PK PF00224.16 EIW86820.1 - 4.8e-164 545.0 0.5 6e-164 544.7 0.3 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EIW86820.1 - 4.9e-32 109.9 0.0 1.4e-31 108.4 0.0 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EIW86820.1 - 3.8e-05 22.6 0.5 9.6e-05 21.3 0.4 1.7 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EIW86820.1 - 0.00062 18.7 0.1 0.0097 14.8 0.0 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain LAG1-DNAbind PF09271.6 EIW86821.1 - 1.8e-26 93.2 0.4 6.2e-25 88.3 0.3 2.4 1 1 0 1 1 1 1 LAG1, DNA binding BTD PF09270.5 EIW86821.1 - 1.7e-25 89.5 0.0 6.3e-25 87.7 0.0 1.9 3 0 0 3 3 3 1 Beta-trefoil DNA-binding domain DUF4203 PF13886.1 EIW86823.1 - 3.2e-36 124.7 26.2 3.2e-36 124.7 18.2 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4203) 7TMR-DISM_7TM PF07695.6 EIW86823.1 - 0.069 12.8 22.5 0.36 10.4 8.0 2.3 1 1 1 2 2 2 0 7TM diverse intracellular signalling DEAD PF00270.24 EIW86824.1 - 4e-16 58.9 0.0 1.6e-15 56.9 0.0 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EIW86824.1 - 5.3e-09 35.8 0.0 1.3e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Sugar_tr PF00083.19 EIW86825.1 - 4.7e-101 338.6 17.3 5.4e-101 338.4 12.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW86825.1 - 2.8e-26 92.1 48.4 3.2e-24 85.3 18.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily PPR_2 PF13041.1 EIW86826.1 - 7.1e-41 137.9 0.7 7e-09 35.5 0.0 8.8 5 2 3 8 8 8 8 PPR repeat family PPR_3 PF13812.1 EIW86826.1 - 3e-32 108.1 0.8 0.00019 21.4 0.0 11.3 11 0 0 11 11 11 7 Pentatricopeptide repeat domain PPR PF01535.15 EIW86826.1 - 2.1e-18 64.9 2.1 0.0014 18.4 0.0 10.3 11 0 0 11 11 11 4 PPR repeat PPR_1 PF12854.2 EIW86826.1 - 2.4e-13 49.3 4.8 0.054 12.9 0.0 7.7 10 0 0 10 10 10 4 PPR repeat TPR_14 PF13428.1 EIW86826.1 - 0.0092 16.5 4.3 77 4.3 0.1 6.0 6 1 1 7 7 7 0 Tetratricopeptide repeat Pro_isomerase PF00160.16 EIW86827.1 - 2.7e-44 151.0 0.0 4.5e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 EIW86827.1 - 0.002 17.3 0.2 0.021 14.0 0.0 2.4 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.10 EIW86827.1 - 0.13 12.2 0.0 0.3 11.0 0.0 1.6 1 0 0 1 1 1 0 U-box domain Snf7 PF03357.16 EIW86828.1 - 9.6e-31 106.4 4.1 1.1e-30 106.2 2.8 1.0 1 0 0 1 1 1 1 Snf7 G_glu_transpept PF01019.16 EIW86829.1 - 1.4e-146 488.9 0.0 1.6e-146 488.7 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase RdRP PF05183.7 EIW86830.1 - 2.3e-128 429.4 0.0 2.9e-128 429.1 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase Ribosomal_S17 PF00366.15 EIW86831.1 - 1.6e-09 37.6 1.8 1.9e-07 30.9 1.2 2.1 1 1 0 1 1 1 1 Ribosomal protein S17 MFS_1 PF07690.11 EIW86832.1 - 1.5e-41 142.2 35.9 1.5e-41 142.2 24.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW86832.1 - 6.6e-13 48.0 19.8 1.9e-12 46.5 13.7 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EIW86832.1 - 2.6e-12 45.7 2.3 4.4e-12 44.9 1.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) WD40 PF00400.27 EIW86833.1 - 2.2e-06 27.3 13.1 8.8e-05 22.2 0.0 5.9 7 0 0 7 7 7 2 WD domain, G-beta repeat IKI3 PF04762.7 EIW86833.1 - 0.0032 15.3 0.0 0.8 7.4 0.0 3.0 2 1 1 3 3 3 2 IKI3 family Lactonase PF10282.4 EIW86833.1 - 0.0038 16.3 0.1 18 4.3 0.0 3.1 2 1 1 3 3 3 3 Lactonase, 7-bladed beta-propeller Peptidase_M41 PF01434.13 EIW86834.1 - 4.5e-72 241.9 0.0 6.8e-72 241.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EIW86834.1 - 2.1e-42 144.4 0.0 4.9e-42 143.2 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EIW86834.1 - 7.8e-11 42.1 0.0 1.6e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.1 EIW86834.1 - 0.0012 19.0 0.1 0.081 13.0 0.0 2.7 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 EIW86834.1 - 0.0032 16.2 0.0 0.0057 15.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EIW86834.1 - 0.0032 17.1 0.3 0.0096 15.6 0.2 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EIW86834.1 - 0.0042 17.1 0.2 0.085 12.8 0.1 2.6 1 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EIW86834.1 - 0.013 16.3 0.1 0.047 14.5 0.0 2.1 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.16 EIW86834.1 - 0.016 14.4 0.1 0.36 9.9 0.1 2.6 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EIW86834.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EIW86834.1 - 0.019 14.3 0.4 0.064 12.6 0.3 1.9 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EIW86834.1 - 0.022 13.8 0.0 0.056 12.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin RuvB_N PF05496.7 EIW86834.1 - 0.025 13.6 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EIW86834.1 - 0.027 14.1 0.1 0.1 12.2 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EIW86834.1 - 0.036 13.9 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) MFS_1 PF07690.11 EIW86835.1 - 7.5e-24 84.0 30.1 7.5e-24 84.0 20.9 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UreD PF01774.12 EIW86836.1 - 2.4e-52 177.4 0.0 2.8e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein NRDE-2 PF08424.5 EIW86838.1 - 2.1e-55 187.8 1.5 9.3e-54 182.4 0.3 2.3 2 0 0 2 2 2 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 EIW86838.1 - 0.0062 17.0 8.8 11 6.9 0.0 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EIW86838.1 - 0.069 13.8 6.8 6.6 7.5 0.0 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat UPF0113 PF03657.8 EIW86839.1 - 3.9e-10 39.6 0.0 5.1e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) AMNp_N PF10423.4 EIW86839.1 - 0.057 13.0 0.0 0.2 11.2 0.0 2.0 1 1 0 1 1 1 0 Bacterial AMP nucleoside phosphorylase N-terminus SNARE_assoc PF09335.6 EIW86840.1 - 1.3e-10 41.5 5.6 2.9e-10 40.4 3.9 1.6 1 0 0 1 1 1 1 SNARE associated Golgi protein Sec39 PF08314.6 EIW86841.1 - 1.7e-61 208.1 0.0 2.4e-61 207.6 0.0 1.2 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Pep3_Vps18 PF05131.9 EIW86842.1 - 4.6e-41 139.6 0.0 1.1e-40 138.4 0.0 1.7 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EIW86842.1 - 1.6e-11 43.9 2.6 3.2e-06 26.7 0.1 3.9 4 0 0 4 4 4 2 Region in Clathrin and VPS Vps39_2 PF10367.4 EIW86842.1 - 5.4e-07 29.7 0.1 1.3e-06 28.5 0.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.1 EIW86842.1 - 0.00012 21.7 2.9 0.00015 21.4 0.8 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EIW86842.1 - 0.00045 19.9 3.3 0.0015 18.2 1.1 2.3 2 0 0 2 2 2 1 Ring finger domain DUF1664 PF07889.7 EIW86842.1 - 0.011 15.5 1.5 0.023 14.4 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TPR_2 PF07719.12 EIW86842.1 - 0.019 14.8 6.0 0.8 9.7 0.2 3.0 1 1 1 2 2 2 0 Tetratricopeptide repeat zf-C3HC4_3 PF13920.1 EIW86842.1 - 0.048 13.3 0.8 0.58 9.8 0.4 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_16 PF13432.1 EIW86842.1 - 0.054 14.1 1.8 18 6.1 0.2 3.5 1 1 1 2 2 2 0 Tetratricopeptide repeat Rabaptin PF03528.10 EIW86842.1 - 0.059 13.2 0.1 0.16 11.9 0.1 1.6 1 0 0 1 1 1 0 Rabaptin zf-C3HC4_2 PF13923.1 EIW86842.1 - 0.066 13.2 2.9 0.086 12.8 0.7 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_1 PF00515.23 EIW86842.1 - 0.072 12.7 5.2 0.19 11.4 0.3 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EIW86842.1 - 0.08 12.6 3.2 3 7.5 0.1 3.0 1 1 1 2 2 2 0 TPR repeat Sec2p PF06428.6 EIW86842.1 - 0.21 11.4 2.5 13 5.6 0.2 2.4 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p TPR_8 PF13181.1 EIW86842.1 - 0.24 11.2 4.3 11 6.1 0.3 3.6 2 1 1 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EIW86842.1 - 1.4 9.1 6.4 0.45 10.6 0.4 3.1 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 zf-C3HC4 PF00097.20 EIW86842.1 - 2.4 7.8 6.5 0.26 10.9 1.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TPR_7 PF13176.1 EIW86842.1 - 3.3 7.7 5.3 32 4.6 0.1 4.2 4 1 0 4 4 3 0 Tetratricopeptide repeat His_Phos_1 PF00300.17 EIW86843.1 - 6.7e-30 104.2 0.0 8.2e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) WEMBL PF05701.6 EIW86844.1 - 4.4e-05 22.1 141.3 0.046 12.1 15.1 5.0 1 1 4 5 5 5 4 Weak chloroplast movement under blue light Filament PF00038.16 EIW86844.1 - 8.2e-05 22.2 107.5 0.0013 18.2 16.9 4.5 1 1 3 4 4 4 3 Intermediate filament protein Spc7 PF08317.6 EIW86844.1 - 0.00073 18.2 108.9 0.083 11.5 8.2 7.1 2 2 4 7 7 7 6 Spc7 kinetochore protein APG6 PF04111.7 EIW86844.1 - 8.7 5.2 116.0 0.33 9.9 7.0 6.9 2 1 4 7 7 7 0 Autophagy protein Apg6 Mito_carr PF00153.22 EIW86845.1 - 2.1e-27 94.6 9.1 6.8e-12 44.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TRAPPC-Trs85 PF12739.2 EIW86847.1 - 1.1e-27 96.7 0.0 2.8e-24 85.5 0.0 2.4 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.6 EIW86847.1 - 0.19 9.0 0.0 1.3 6.2 0.0 1.9 1 1 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Dehydrin PF00257.14 EIW86848.1 - 0.0025 18.1 0.6 0.0032 17.7 0.4 1.2 1 0 0 1 1 1 1 Dehydrin FlgM PF04316.8 EIW86848.1 - 1.1 9.2 4.1 2 8.4 2.8 1.4 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM EVC2_like PF12297.3 EIW86848.1 - 2.6 6.5 5.8 3.5 6.1 4.0 1.0 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein OPT PF03169.10 EIW86850.1 - 7.7e-198 658.8 57.9 8.8e-198 658.6 40.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein LCCL PF03815.14 EIW86851.1 - 1.5e-14 53.7 0.0 2.6e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 LCCL domain Seipin PF06775.9 EIW86853.1 - 5.9e-11 42.2 0.0 1.5e-10 40.8 0.0 1.7 1 1 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Hepatitis_core PF00906.15 EIW86853.1 - 0.7 9.5 3.6 1.4 8.5 2.5 1.5 1 0 0 1 1 1 0 Hepatitis core antigen adh_short PF00106.20 EIW86854.1 - 1.5e-29 103.0 0.3 2.1e-29 102.5 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EIW86854.1 - 4.5e-21 75.7 0.1 6.9e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EIW86854.1 - 1.3e-09 38.0 0.3 4.5e-09 36.2 0.2 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EIW86854.1 - 0.0077 15.6 0.1 0.041 13.3 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EIW86854.1 - 0.11 11.5 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_10 PF13460.1 EIW86854.1 - 0.11 12.4 0.2 0.35 10.8 0.1 1.8 1 1 0 1 1 1 0 NADH(P)-binding LMWPc PF01451.16 EIW86855.1 - 9.7e-37 126.3 0.0 1.1e-36 126.2 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Aldedh PF00171.17 EIW86856.1 - 3.7e-127 424.4 0.5 4.4e-127 424.2 0.3 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EIW86856.1 - 0.0096 14.6 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) GDI PF00996.13 EIW86858.1 - 2.1e-205 682.1 0.2 2.4e-205 681.9 0.1 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Rav1p_C PF12234.3 EIW86859.1 - 3.2e-180 600.4 0.0 5.1e-180 599.7 0.0 1.3 1 1 0 1 1 1 1 RAVE protein 1 C terminal Mito_carr PF00153.22 EIW86860.1 - 7.9e-68 224.2 4.6 1.7e-22 78.9 0.1 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein Fasciclin PF02469.17 EIW86860.1 - 1.2e-62 209.6 0.0 4.8e-18 65.4 0.0 5.3 5 0 0 5 5 5 5 Fasciclin domain DUF4098 PF13345.1 EIW86860.1 - 0.093 12.6 1.4 0.23 11.4 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4098) Peptidase_M13_N PF05649.8 EIW86860.1 - 0.12 11.3 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M13 DUF619 PF04768.8 EIW86861.1 - 8.4e-36 122.9 0.0 3.4e-20 72.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF619) F-box PF00646.28 EIW86862.1 - 1.9e-07 30.5 1.7 4.4e-07 29.3 0.2 2.3 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EIW86862.1 - 2.5e-07 30.3 0.9 6.8e-07 28.9 0.6 1.8 1 0 0 1 1 1 1 F-box-like UQ_con PF00179.21 EIW86863.1 - 1e-20 73.6 0.0 2.4e-20 72.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SKN1 PF03935.10 EIW86864.1 - 4.3e-192 638.7 3.9 5.2e-192 638.4 2.7 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) APH PF01636.18 EIW86865.1 - 1.2e-12 48.1 0.0 1.7e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EIW86865.1 - 1.8e-05 24.0 0.0 6.4e-05 22.2 0.0 1.7 2 0 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.6 EIW86865.1 - 0.00015 20.5 0.0 0.00022 19.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.15 EIW86865.1 - 0.07 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 EIW86865.1 - 0.084 11.8 0.0 0.6 9.0 0.0 2.1 2 0 0 2 2 2 0 Fructosamine kinase SNAPc_SNAP43 PF09808.4 EIW86866.1 - 1.9e-06 27.6 0.0 2.7e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 Ima1_N PF09779.4 EIW86867.1 - 1.8e-27 96.4 2.8 2.8e-27 95.8 1.9 1.3 1 0 0 1 1 1 1 Ima1 N-terminal domain Tox-PL PF15644.1 EIW86867.1 - 0.14 12.9 0.5 2.1 9.1 0.1 2.4 2 0 0 2 2 2 0 Papain fold toxin 1 PMP1_2 PF08114.6 EIW86868.1 - 0.38 10.2 2.7 5.6 6.5 0.2 2.3 2 0 0 2 2 2 0 ATPase proteolipid family Pex14_N PF04695.8 EIW86868.1 - 5.6 7.0 14.8 0.53 10.3 1.1 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hepar_II_III PF07940.8 EIW86869.1 - 2.2e-07 30.7 0.4 4.2e-07 29.8 0.3 1.4 1 0 0 1 1 1 1 Heparinase II/III-like protein Cu_amine_oxidN1 PF07833.6 EIW86869.1 - 0.065 13.5 0.1 0.21 11.9 0.1 1.8 1 0 0 1 1 1 0 Copper amine oxidase N-terminal domain DUF1628 PF07790.6 EIW86869.1 - 0.53 11.0 2.8 0.7 10.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1628) Thiolase_N PF00108.18 EIW86870.1 - 1.3e-69 234.1 0.5 2.4e-69 233.2 0.4 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EIW86870.1 - 2e-45 153.1 0.5 6e-45 151.6 0.3 1.8 2 0 0 2 2 2 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EIW86870.1 - 0.0013 18.3 0.2 0.031 13.9 0.0 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ACP_syn_III_C PF08541.5 EIW86870.1 - 0.0046 16.9 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.21 EIW86870.1 - 0.022 14.2 0.4 0.055 12.9 0.3 1.7 1 0 0 1 1 1 0 Beta-ketoacyl synthase, N-terminal domain Ribosomal_L1 PF00687.16 EIW86871.1 - 2.7e-50 170.7 2.6 3.3e-50 170.4 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Yae1_N PF09811.4 EIW86872.1 - 0.016 14.7 3.4 0.03 13.8 2.3 1.4 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Laminin_II PF06009.7 EIW86872.1 - 0.017 14.8 5.0 0.029 14.1 3.4 1.3 1 0 0 1 1 1 0 Laminin Domain II GAS PF13851.1 EIW86872.1 - 0.049 12.8 5.5 0.089 11.9 3.8 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding ADIP PF11559.3 EIW86872.1 - 0.088 12.7 11.1 0.17 11.7 7.7 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding IncA PF04156.9 EIW86872.1 - 1.3 8.5 12.4 2.7 7.5 8.6 1.4 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EIW86872.1 - 1.7 6.3 4.9 2.4 5.8 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3347 PF11827.3 EIW86872.1 - 2.1 8.2 3.9 5 7.0 2.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3347) SSF PF00474.12 EIW86873.1 - 2.6e-21 75.7 34.4 3.4e-21 75.3 23.9 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family IRK PF01007.15 EIW86874.1 - 0.44 9.2 2.1 0.43 9.3 1.5 1.0 1 0 0 1 1 1 0 Inward rectifier potassium channel TatD_DNase PF01026.16 EIW86875.1 - 3.1e-47 160.9 0.0 3.7e-47 160.6 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Glyco_transf_21 PF13506.1 EIW86876.1 - 1.2e-25 89.8 0.5 4.7e-18 65.0 0.0 2.4 2 1 0 2 2 2 2 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 EIW86876.1 - 1.3e-21 77.4 0.0 1.8e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EIW86876.1 - 2e-07 30.9 3.1 2e-07 30.9 2.2 1.6 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EIW86876.1 - 3.3e-07 30.1 0.0 4.9e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Sec3_C PF09763.4 EIW86877.1 - 2.6e-157 524.9 1.5 4.2e-157 524.3 1.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 EIW86877.1 - 1.1e-21 76.4 0.0 2.9e-21 75.1 0.0 1.8 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Vps52 PF04129.7 EIW86877.1 - 0.051 12.0 4.6 0.052 12.0 1.8 1.8 2 0 0 2 2 2 0 Vps52 / Sac2 family Zn_clus PF00172.13 EIW86878.1 - 1.8e-07 30.9 10.6 3.2e-07 30.1 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EIW86878.1 - 5.2e-06 25.5 0.0 1.4e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain SNF2_N PF00176.18 EIW86879.1 - 2e-68 230.4 0.0 1.8e-46 158.3 0.0 2.4 2 1 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW86879.1 - 5.1e-11 42.2 0.0 3.4e-10 39.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EIW86879.1 - 8.2e-05 22.2 5.2 8.2e-05 22.2 3.6 2.3 3 0 0 3 3 3 1 zinc-RING finger domain DUF3987 PF13148.1 EIW86879.1 - 0.028 12.9 0.6 0.4 9.1 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3987) MSV199 PF10553.4 EIW86879.1 - 0.067 13.0 0.3 0.3 10.9 0.6 1.7 2 0 0 2 2 2 0 MSV199 domain Ribonucleas_3_3 PF14622.1 EIW86880.1 - 4.5e-11 42.7 0.0 6.6e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 EIW86880.1 - 2.2e-09 37.7 0.1 3.9e-09 36.9 0.1 1.4 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 EIW86880.1 - 0.0013 19.1 0.0 0.0021 18.4 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain SNF2_N PF00176.18 EIW86881.1 - 1.5e-63 214.3 0.9 2.1e-63 213.8 0.6 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 EIW86881.1 - 7.1e-20 71.0 0.5 1.5e-19 69.9 0.4 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 EIW86881.1 - 4.5e-14 52.0 0.0 2.9e-13 49.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-PHD-like PF15446.1 EIW86881.1 - 6.9e-09 35.2 8.4 4.2e-05 22.9 0.2 3.0 3 0 0 3 3 3 2 PHD/FYVE-zinc-finger like domain Chromo PF00385.19 EIW86881.1 - 4.4e-08 32.6 1.7 0.00024 20.7 0.1 3.2 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain DEAD PF00270.24 EIW86881.1 - 3.7e-05 23.2 0.0 9.5e-05 21.9 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase SRP54 PF00448.17 EIW86881.1 - 0.26 10.6 0.1 0.55 9.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Sec8_exocyst PF04048.9 EIW86882.1 - 3.9e-32 110.8 0.8 2.1e-31 108.4 0.3 2.3 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EIW86882.1 - 6e-06 25.3 0.5 1.3e-05 24.3 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec5 PF15469.1 EIW86882.1 - 0.039 13.6 0.2 5.5 6.6 0.0 2.5 2 0 0 2 2 2 0 Exocyst complex component Sec5 Complex1_LYR PF05347.10 EIW86883.1 - 0.00027 20.6 1.7 0.00053 19.7 1.2 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EIW86883.1 - 0.0028 17.8 1.9 0.0053 16.9 1.3 1.4 1 0 0 1 1 1 1 Complex1_LYR-like MMR_HSR1 PF01926.18 EIW86884.1 - 6.7e-16 58.2 0.0 9.4e-15 54.5 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIW86884.1 - 2e-05 23.9 0.0 0.00014 21.1 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EIW86884.1 - 9.5e-05 21.6 0.0 0.0002 20.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EIW86884.1 - 0.0015 17.7 0.0 0.0037 16.3 0.0 1.7 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.18 EIW86884.1 - 0.0043 16.8 0.0 0.012 15.4 0.0 1.8 1 0 0 1 1 1 1 Dynamin family Miro PF08477.8 EIW86884.1 - 0.029 14.8 0.0 0.08 13.4 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein GspH PF12019.3 EIW86884.1 - 0.036 14.2 0.6 0.096 12.8 0.0 2.1 2 0 0 2 2 2 0 Type II transport protein GspH Pkinase PF00069.20 EIW86885.1 - 2.1e-49 168.0 0.0 2.7e-49 167.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW86885.1 - 5.2e-29 101.1 0.0 6.7e-29 100.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW86885.1 - 0.0011 17.9 0.0 0.0035 16.3 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EIW86885.1 - 0.0022 17.0 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW86885.1 - 0.034 13.8 0.0 0.87 9.2 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family FHA PF00498.21 EIW86885.1 - 0.069 13.2 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 FHA domain Esterase PF00756.15 EIW86886.1 - 2.6e-41 141.6 0.0 3.3e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.2 EIW86886.1 - 1.2e-06 28.3 0.1 1.8e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EIW86886.1 - 0.055 12.3 0.0 0.087 11.7 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase_phd PF10503.4 EIW86886.1 - 0.058 12.6 0.0 0.095 11.9 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase PGAP1 PF07819.8 EIW86887.1 - 1.7e-07 31.0 0.1 3.3e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EIW86887.1 - 2.4e-05 24.1 0.0 8.2e-05 22.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW86887.1 - 6.7e-05 22.8 0.2 6.7e-05 22.8 0.1 2.4 1 1 1 2 2 2 1 Alpha/beta hydrolase family DUF676 PF05057.9 EIW86887.1 - 0.0042 16.4 0.1 0.013 14.7 0.1 1.8 1 1 0 1 1 1 1 Putative serine esterase (DUF676) UPF0227 PF05728.7 EIW86887.1 - 0.018 14.7 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.15 EIW86887.1 - 0.028 13.9 0.0 0.05 13.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF915 PF06028.6 EIW86887.1 - 0.031 13.3 0.0 0.11 11.5 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.15 EIW86887.1 - 0.12 12.5 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain LCAT PF02450.10 EIW86887.1 - 0.14 11.1 0.0 0.22 10.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase zf-C2H2_4 PF13894.1 EIW86888.1 - 0.0068 16.6 1.2 0.012 15.9 0.8 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EIW86888.1 - 0.0075 16.5 0.9 0.014 15.6 0.6 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2HC_2 PF13913.1 EIW86888.1 - 0.19 11.4 0.4 0.19 11.4 0.3 1.9 2 0 0 2 2 2 0 zinc-finger of a C2HC-type S1 PF00575.18 EIW86889.1 - 1.3e-60 201.3 26.1 5.6e-14 51.9 0.3 10.7 10 0 0 10 10 10 9 S1 RNA binding domain TPR_19 PF14559.1 EIW86889.1 - 2.5e-07 30.9 0.0 0.0062 16.8 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EIW86889.1 - 2.9e-06 27.4 0.0 2 9.2 0.0 4.6 3 1 1 4 4 4 2 Tetratricopeptide repeat Suf PF05843.9 EIW86889.1 - 3e-06 27.1 7.1 0.005 16.6 0.3 3.8 2 1 1 3 3 3 2 Suppressor of forked protein (Suf) TPR_16 PF13432.1 EIW86889.1 - 3.3e-05 24.4 0.0 0.46 11.2 0.0 3.8 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EIW86889.1 - 6e-05 22.9 0.9 3.4 7.6 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat NRDE-2 PF08424.5 EIW86889.1 - 0.00023 20.1 8.9 0.00056 18.8 3.9 2.3 1 1 1 2 2 2 1 NRDE-2, necessary for RNA interference TPR_15 PF13429.1 EIW86889.1 - 0.0032 16.5 4.3 0.021 13.9 0.5 2.7 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EIW86889.1 - 0.0046 16.5 0.0 0.028 14.0 0.0 2.1 2 0 0 2 2 2 1 TPR repeat RNA_pol_Rbc25 PF08292.7 EIW86889.1 - 0.029 14.5 3.4 4.7 7.4 0.0 5.1 5 0 0 5 5 5 0 RNA polymerase III subunit Rpc25 TPR_6 PF13174.1 EIW86889.1 - 0.034 14.5 0.8 5.3 7.7 0.0 3.9 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EIW86889.1 - 0.04 13.7 1.4 0.21 11.4 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat SPOB_a PF14689.1 EIW86889.1 - 0.45 10.1 1.9 1.5 8.4 0.0 2.8 3 0 0 3 3 3 0 Sensor_kinase_SpoOB-type, alpha-helical domain zf-met PF12874.2 EIW86890.1 - 1.5e-06 28.1 1.2 2.7e-06 27.3 0.6 1.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type PRP4 PF08799.6 EIW86890.1 - 0.017 14.3 0.6 0.03 13.5 0.4 1.4 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CactinC_cactus PF09732.4 EIW86890.1 - 0.082 12.5 0.2 0.22 11.1 0.1 1.7 1 1 0 1 1 1 0 Cactus-binding C-terminus of cactin protein Ribonuclease PF00545.15 EIW86891.1 - 6.6e-17 61.3 0.6 1e-16 60.7 0.4 1.3 1 1 0 1 1 1 1 ribonuclease SWIM PF04434.12 EIW86891.1 - 0.097 12.1 1.6 1.6 8.2 0.1 2.5 2 0 0 2 2 2 0 SWIM zinc finger p450 PF00067.17 EIW86892.1 - 6.4e-47 160.1 0.1 7.6e-47 159.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pal1 PF08316.6 EIW86893.1 - 0.016 15.6 1.7 0.023 15.1 0.1 2.1 2 0 0 2 2 2 0 Pal1 cell morphology protein Drc1-Sld2 PF11719.3 EIW86894.1 - 7.8e-17 61.4 1.7 7.8e-17 61.4 1.2 2.8 1 1 1 2 2 2 1 DNA replication and checkpoint protein Amelogenin PF02948.10 EIW86894.1 - 0.33 11.5 11.1 0.87 10.1 7.7 1.7 1 0 0 1 1 1 0 Amelogenin F-box-like PF12937.2 EIW86895.1 - 0.0011 18.6 0.1 0.0042 16.7 0.0 2.0 1 0 0 1 1 1 1 F-box-like TetR_C PF02909.12 EIW86895.1 - 0.18 11.4 0.6 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 Tetracyclin repressor, C-terminal all-alpha domain PCI PF01399.22 EIW86896.1 - 3.6e-20 72.2 0.2 1.1e-17 64.2 0.0 2.8 2 0 0 2 2 2 2 PCI domain MHC_I PF00129.13 EIW86896.1 - 0.0049 16.2 0.2 0.017 14.4 0.0 2.0 2 0 0 2 2 2 1 Class I Histocompatibility antigen, domains alpha 1 and 2 Pup PF05639.6 EIW86896.1 - 0.086 13.3 0.1 0.26 11.8 0.1 1.8 1 0 0 1 1 1 0 Pup-like protein Rnk_N PF14760.1 EIW86896.1 - 1.2 9.2 4.0 8.7 6.5 0.0 2.9 3 0 0 3 3 3 0 Rnk N-terminus MRP-S25 PF13741.1 EIW86897.1 - 1.8e-46 158.5 5.0 4.9e-46 157.0 3.4 1.7 1 1 0 1 1 1 1 Mitochondrial ribosomal protein S25 MRP-S23 PF10484.4 EIW86897.1 - 0.00027 20.8 2.0 0.0026 17.6 1.1 2.4 1 1 1 2 2 2 1 Mitochondrial ribosomal protein S23 Med7 PF05983.6 EIW86898.1 - 5.5e-27 94.5 0.0 6.9e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 MED7 protein Glyco_hydro_47 PF01532.15 EIW86899.1 - 8.2e-137 456.5 0.0 9.8e-137 456.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 RskA PF10099.4 EIW86899.1 - 0.19 11.4 0.1 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Anti-sigma-K factor rskA B12D PF06522.6 EIW86900.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Gp5_C PF06715.7 EIW86902.1 - 0.099 12.5 0.1 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 Gp5 C-terminal repeat (3 copies) Pal1 PF08316.6 EIW86904.1 - 0.061 13.7 0.1 0.14 12.6 0.1 1.6 1 0 0 1 1 1 0 Pal1 cell morphology protein GARS_A PF01071.14 EIW86905.1 - 4.4e-79 264.5 0.0 6.6e-79 263.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EIW86905.1 - 1.1e-35 122.1 0.2 6.1e-35 119.6 0.0 2.5 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EIW86905.1 - 5.1e-26 91.5 0.0 1.4e-25 90.1 0.0 1.8 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EIW86905.1 - 1.4e-25 89.2 0.2 5.2e-25 87.4 0.2 1.9 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EIW86905.1 - 6.7e-17 61.5 1.6 2.8e-16 59.5 0.3 2.7 2 1 1 3 3 3 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EIW86905.1 - 1e-10 41.6 0.0 2.5e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EIW86905.1 - 5e-07 28.7 0.0 1.2e-06 27.5 0.0 1.5 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon CPSase_L_D2 PF02786.12 EIW86905.1 - 0.00011 21.5 0.0 0.0002 20.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 EIW86905.1 - 0.074 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain Ank PF00023.25 EIW86906.1 - 3.1e-11 42.5 0.2 2.8e-07 30.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EIW86906.1 - 2.3e-09 37.4 0.0 4.8e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EIW86906.1 - 2.5e-07 30.7 1.0 6.9e-07 29.3 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EIW86906.1 - 9e-06 25.4 0.0 4.4e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EIW86906.1 - 0.00016 22.0 0.0 0.00038 20.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) zf-CCCH_2 PF14608.1 EIW86906.1 - 0.26 11.3 7.5 2.3 8.3 0.1 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 EIW86906.1 - 0.84 9.3 7.7 0.12 12.0 0.8 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Mif2_N PF15624.1 EIW86906.1 - 1.3 9.5 6.2 1.3 9.6 2.8 2.0 1 1 1 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal NAD_Gly3P_dh_C PF07479.9 EIW86907.1 - 7.5e-47 158.7 0.5 1e-46 158.3 0.3 1.2 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.18 EIW86907.1 - 1.1e-34 119.4 0.0 1.9e-34 118.6 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EIW86907.1 - 8.7e-07 28.5 0.0 1.6e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 EIW86907.1 - 0.0001 22.6 0.0 0.00033 21.0 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EIW86907.1 - 0.0013 18.5 0.0 0.0028 17.5 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.22 EIW86907.1 - 0.0018 18.6 0.1 2.4 8.6 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EIW86907.1 - 0.039 14.2 0.0 0.07 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.13 EIW86907.1 - 0.055 13.4 0.0 2.1 8.3 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Syntaxin PF00804.20 EIW86908.1 - 9.1e-18 64.3 6.9 1.1e-17 64.0 1.8 2.7 2 1 0 2 2 2 1 Syntaxin SNARE PF05739.14 EIW86908.1 - 6e-15 54.6 3.1 7e-15 54.4 0.1 2.6 3 0 0 3 3 3 1 SNARE domain Syntaxin-18_N PF10496.4 EIW86908.1 - 4.1e-05 23.3 1.9 0.0022 17.7 0.1 3.2 3 1 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus Sed5p PF11416.3 EIW86908.1 - 0.0024 17.2 0.2 0.0074 15.6 0.1 1.9 1 0 0 1 1 1 1 Integral membrane protein Sed5p HrpB7 PF09486.5 EIW86908.1 - 0.036 13.9 0.3 0.14 12.0 0.1 2.0 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) NPV_P10 PF05531.7 EIW86908.1 - 0.18 12.0 3.8 0.64 10.3 0.2 2.8 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein RasGAP_C PF03836.10 EIW86908.1 - 0.38 10.4 7.6 1.6 8.4 0.0 3.4 3 1 0 3 3 3 0 RasGAP C-terminus DUF1664 PF07889.7 EIW86908.1 - 1.3 8.8 6.0 7.7 6.3 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Cluap1 PF10234.4 EIW86908.1 - 2 7.5 8.7 0.39 9.8 0.6 2.7 2 1 1 3 3 3 0 Clusterin-associated protein-1 FliD_N PF02465.13 EIW86908.1 - 5.8 7.3 9.9 1.5 9.2 0.1 3.3 3 1 1 4 4 4 0 Flagellar hook-associated protein 2 N-terminus RRM_6 PF14259.1 EIW86909.1 - 1.1e-08 34.9 0.0 2.2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EIW86909.1 - 4.6e-06 26.1 0.0 0.00012 21.6 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW86909.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MAPEG PF01124.13 EIW86911.1 - 6.4e-20 71.0 0.7 8.5e-20 70.6 0.5 1.1 1 0 0 1 1 1 1 MAPEG family WD40 PF00400.27 EIW86912.1 - 7.5e-25 85.8 8.2 1.5e-09 37.3 0.2 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EIW86912.1 - 2.7e-17 62.4 0.0 5.9e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 EIW86912.1 - 8.7e-07 28.8 0.0 3.5e-05 23.6 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Nucleoplasmin PF03066.10 EIW86912.1 - 0.042 13.3 0.0 0.042 13.3 0.0 2.5 2 1 1 3 3 3 0 Nucleoplasmin Neugrin PF06413.6 EIW86912.1 - 0.81 9.4 5.6 0.26 11.0 1.1 2.0 2 0 0 2 2 2 0 Neugrin PA28_beta PF02252.13 EIW86913.1 - 1.3e-44 151.3 0.2 1.7e-44 150.9 0.2 1.1 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 EIW86913.1 - 0.00089 19.3 0.0 0.0048 17.0 0.0 2.2 2 0 0 2 2 2 1 Proteasome activator pa28 alpha subunit DUF3591 PF12157.3 EIW86914.1 - 5.2e-181 602.0 2.7 7.2e-181 601.5 1.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) zf-CCHC_6 PF15288.1 EIW86914.1 - 0.00016 21.2 2.4 0.00036 20.1 1.7 1.6 1 0 0 1 1 1 1 Zinc knuckle EF-hand_7 PF13499.1 EIW86915.1 - 3.6e-12 46.2 0.3 9.1e-05 22.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EIW86915.1 - 5.9e-12 43.9 2.4 0.00015 20.8 0.0 3.6 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.1 EIW86915.1 - 9.5e-12 43.7 0.5 9.7e-05 21.9 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 EIW86915.1 - 6.4e-05 22.1 0.2 0.12 11.7 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EIW86915.1 - 0.0017 17.9 4.9 0.12 12.0 1.6 3.2 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.1 EIW86915.1 - 0.039 13.8 0.0 12 5.9 0.0 3.3 2 1 0 2 2 2 0 EF-hand domain VHS PF00790.14 EIW86917.1 - 7.7e-27 93.6 0.0 1.6e-26 92.6 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EIW86917.1 - 1.8e-06 27.8 0.3 1e-05 25.4 0.1 2.3 2 0 0 2 2 2 1 GAT domain DDRGK PF09756.4 EIW86917.1 - 0.045 13.1 11.4 0.097 12.0 7.9 1.5 1 0 0 1 1 1 0 DDRGK domain Herpes_DNAp_acc PF04929.7 EIW86917.1 - 0.24 10.3 6.1 0.41 9.5 4.2 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor eIF3_subunit PF08597.5 EIW86917.1 - 1.3 8.4 12.6 5.3 6.5 7.7 2.2 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit PI-PLC-X PF00388.14 EIW86918.1 - 0.0027 17.0 0.0 0.0046 16.3 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Serglycin PF04360.7 EIW86918.1 - 0.5 10.0 3.2 0.88 9.2 2.2 1.4 1 0 0 1 1 1 0 Serglycin Zn_clus PF00172.13 EIW86919.1 - 5.7e-09 35.7 5.3 8.3e-09 35.2 3.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 EIW86919.1 - 0.28 9.3 12.7 0.29 9.3 8.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cytochrom_C PF00034.16 EIW86919.1 - 0.31 11.9 9.9 0.18 12.6 1.6 2.4 2 1 0 2 2 2 0 Cytochrome c APC_CDC26 PF10471.4 EIW86919.1 - 6.9 7.4 12.0 9.6 7.0 6.6 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 NIF PF03031.13 EIW86920.1 - 6.6e-26 90.8 0.0 1.2e-22 80.3 0.0 2.3 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EIW86920.1 - 3.7e-10 39.4 1.7 2.5e-09 36.8 0.1 2.7 3 0 0 3 3 3 1 twin BRCT domain BRCT PF00533.21 EIW86920.1 - 6.7e-06 26.1 0.0 4.1e-05 23.6 0.0 2.4 1 1 1 2 2 2 1 BRCA1 C Terminus (BRCT) domain GTP_EFTU PF00009.22 EIW86922.1 - 1.9e-63 213.3 0.3 3.2e-63 212.5 0.2 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EIW86922.1 - 3.5e-38 129.8 0.0 2.8e-37 126.9 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EIW86922.1 - 2.1e-21 75.5 0.0 4.3e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EIW86922.1 - 9.1e-14 51.0 0.0 2.7e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EIW86922.1 - 9.7e-13 48.0 0.1 6.4e-12 45.4 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIW86922.1 - 5.7e-06 26.2 0.2 1.2e-05 25.1 0.1 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EIW86922.1 - 0.086 12.3 0.4 0.36 10.3 0.2 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation tRNA-synt_2c PF01411.14 EIW86923.1 - 2.8e-209 695.9 0.0 3.7e-209 695.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EIW86923.1 - 1.8e-16 59.7 0.4 3.9e-16 58.6 0.3 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EIW86923.1 - 2.6e-05 23.8 0.9 2.6e-05 23.8 0.6 2.3 2 0 0 2 2 2 1 DHHA1 domain Acetyltransf_3 PF13302.1 EIW86924.1 - 9.7e-15 54.9 0.0 2.3e-14 53.7 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EIW86924.1 - 0.00054 19.8 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW86924.1 - 0.015 15.3 0.1 0.034 14.1 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EIW86924.1 - 0.017 15.0 0.0 0.025 14.5 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SUR7 PF06687.7 EIW86925.1 - 7.5e-20 71.4 17.7 1e-19 70.9 12.2 1.1 1 0 0 1 1 1 1 SUR7/PalI family Arginase PF00491.16 EIW86926.1 - 2.6e-80 269.7 0.1 3.2e-80 269.4 0.1 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EIW86926.1 - 0.047 13.8 0.0 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 UPF0489 domain Arginase PF00491.16 EIW86927.1 - 5.4e-85 285.0 0.1 6.9e-85 284.7 0.1 1.1 1 0 0 1 1 1 1 Arginase family WD40 PF00400.27 EIW86928.1 - 2.4e-23 81.0 15.0 1.5e-07 31.0 1.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat RicinB_lectin_2 PF14200.1 EIW86928.1 - 0.034 14.5 0.0 0.18 12.2 0.0 2.2 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Nup160 PF11715.3 EIW86928.1 - 0.13 10.3 1.1 0.88 7.6 0.0 2.6 3 1 0 3 3 3 0 Nucleoporin Nup120/160 WD40 PF00400.27 EIW86929.1 - 6.1e-42 140.0 17.4 8e-09 35.0 0.2 7.9 8 0 0 8 8 8 7 WD domain, G-beta repeat LisH PF08513.6 EIW86929.1 - 1.8e-07 30.6 0.1 3.1e-07 29.9 0.1 1.4 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 EIW86929.1 - 0.0098 15.6 0.0 0.55 9.9 0.0 3.0 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Bax1-I PF01027.15 EIW86930.1 - 2.7e-34 118.5 7.0 2.7e-34 118.5 4.8 1.3 2 0 0 2 2 2 1 Inhibitor of apoptosis-promoting Bax1 Sec1 PF00995.18 EIW86931.1 - 3.2e-143 478.3 0.0 3.7e-143 478.1 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF221 PF02714.10 EIW86933.1 - 1.1e-22 80.2 11.7 1.9e-22 79.5 8.1 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 DUF3779 PF12621.3 EIW86933.1 - 3.5e-05 23.6 0.0 8.2e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EIW86933.1 - 0.0025 18.3 0.0 0.0055 17.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) RSN1_TM PF13967.1 EIW86933.1 - 0.0031 17.0 0.0 0.0031 17.0 0.0 3.7 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport TORC_C PF12886.2 EIW86933.1 - 0.05 13.7 0.0 3.3 7.9 0.0 2.8 2 0 0 2 2 2 0 Transducer of regulated CREB activity, C terminus MscS_TM PF12794.2 EIW86934.1 - 0.36 9.3 1.6 0.34 9.4 1.1 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Metallophos PF00149.23 EIW86935.1 - 5.1e-07 29.2 7.8 1.4e-05 24.6 5.4 3.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EIW86935.1 - 0.002 17.9 0.0 0.0079 16.0 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Wbp11 PF09429.5 EIW86936.1 - 3e-19 68.7 11.4 6.5e-19 67.6 7.9 1.5 1 0 0 1 1 1 1 WW domain binding protein 11 NpwBP PF12622.2 EIW86936.1 - 7.9e-16 58.2 7.2 7.9e-16 58.2 5.0 4.5 5 1 0 5 5 5 1 mRNA biogenesis factor DUF972 PF06156.8 EIW86936.1 - 0.35 11.2 5.6 0.75 10.1 3.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Fzo_mitofusin PF04799.8 EIW86936.1 - 2 7.7 3.8 3 7.1 2.6 1.2 1 0 0 1 1 1 0 fzo-like conserved region TMPIT PF07851.8 EIW86936.1 - 6.3 5.7 4.5 9.1 5.2 3.1 1.2 1 0 0 1 1 1 0 TMPIT-like protein F-box-like PF12937.2 EIW86937.1 - 7.6e-05 22.3 0.4 0.00035 20.2 0.0 2.3 2 0 0 2 2 2 1 F-box-like FAD_binding_3 PF01494.14 EIW86938.1 - 6.5e-17 61.6 0.4 4.7e-08 32.4 0.0 2.1 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EIW86938.1 - 4.9e-07 29.6 0.7 1.4e-06 28.2 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EIW86938.1 - 3.7e-06 26.0 1.5 7.3e-06 25.1 1.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW86938.1 - 3e-05 24.3 0.2 7.2e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW86938.1 - 0.0014 18.5 1.2 0.0022 17.8 0.7 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EIW86938.1 - 0.0022 16.5 2.0 0.0033 15.9 1.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Trp_halogenase PF04820.9 EIW86938.1 - 0.0036 16.0 0.0 0.0083 14.8 0.0 1.6 2 0 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.2 EIW86938.1 - 0.0065 15.5 0.2 0.0095 15.0 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EIW86938.1 - 0.011 14.5 2.5 0.015 14.1 1.7 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A 3HCDH_N PF02737.13 EIW86938.1 - 0.019 14.6 2.4 0.035 13.7 1.7 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SE PF08491.5 EIW86938.1 - 0.02 13.7 0.0 0.034 12.9 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase Thi4 PF01946.12 EIW86938.1 - 0.031 13.3 0.6 0.05 12.7 0.4 1.2 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EIW86938.1 - 0.055 13.2 0.6 0.13 12.0 0.4 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding UDPG_MGDP_dh_N PF03721.9 EIW86938.1 - 0.063 12.6 0.5 0.096 12.0 0.3 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_3 PF13738.1 EIW86938.1 - 0.064 13.3 2.6 0.13 12.3 1.8 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Syndecan PF01034.15 EIW86938.1 - 0.066 12.8 0.2 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Syndecan domain NAD_binding_7 PF13241.1 EIW86938.1 - 0.071 13.3 0.0 0.14 12.4 0.0 1.7 1 1 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.16 EIW86938.1 - 0.11 12.2 1.8 1.2 8.9 0.6 2.3 2 0 0 2 2 2 0 ThiF family Lycopene_cycl PF05834.7 EIW86938.1 - 0.15 10.9 0.4 0.29 10.0 0.3 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.11 EIW86938.1 - 0.15 11.5 0.4 0.29 10.5 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 EIW86938.1 - 0.16 12.4 0.3 1.5 9.2 0.2 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_2 PF00890.19 EIW86938.1 - 0.17 10.6 5.5 0.24 10.1 3.2 1.7 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 EIW86939.1 - 1.7e-18 66.8 0.1 9.1e-18 64.4 0.1 2.0 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EIW86939.1 - 4e-07 29.9 1.4 9.2e-07 28.7 1.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EIW86939.1 - 7.6e-06 25.2 0.4 0.051 12.6 0.1 2.4 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase DAO PF01266.19 EIW86939.1 - 9.7e-06 24.7 3.0 9.7e-06 24.7 2.1 1.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EIW86939.1 - 1.3e-05 24.4 0.1 2.2e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EIW86939.1 - 8.3e-05 22.9 2.1 0.00022 21.5 1.5 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EIW86939.1 - 0.0014 18.5 1.4 0.0049 16.7 0.8 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EIW86939.1 - 0.0024 16.8 1.8 0.0035 16.2 1.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.9 EIW86939.1 - 0.0026 16.3 2.7 0.0037 15.7 1.9 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EIW86939.1 - 0.01 15.8 0.3 0.022 14.8 0.2 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW86939.1 - 0.011 14.8 0.4 0.02 13.9 0.3 1.4 1 0 0 1 1 1 0 Thi4 family SE PF08491.5 EIW86939.1 - 0.022 13.5 0.0 0.037 12.8 0.0 1.3 1 0 0 1 1 1 0 Squalene epoxidase FAD_binding_2 PF00890.19 EIW86939.1 - 0.023 13.5 2.6 0.037 12.8 1.8 1.2 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 EIW86939.1 - 0.028 14.0 1.3 0.055 13.1 0.9 1.7 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 EIW86939.1 - 0.036 12.7 0.1 0.064 11.8 0.0 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Syndecan PF01034.15 EIW86939.1 - 0.09 12.4 0.1 0.18 11.4 0.1 1.5 1 0 0 1 1 1 0 Syndecan domain ApbA PF02558.11 EIW86939.1 - 0.13 11.7 0.5 0.34 10.3 0.2 1.7 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.7 EIW86939.1 - 0.13 11.1 0.3 0.24 10.2 0.2 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 EIW86939.1 - 0.14 11.5 0.2 0.29 10.5 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F-box-like PF12937.2 EIW86940.1 - 4.1e-05 23.2 0.4 0.00017 21.2 0.3 2.1 1 1 0 1 1 1 1 F-box-like SH3_1 PF00018.23 EIW86941.1 - 6.4e-12 44.6 0.1 1.1e-11 43.8 0.1 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EIW86941.1 - 5.1e-09 35.4 0.0 1.1e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EIW86941.1 - 4.1e-08 32.6 0.0 6.4e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain PAH PF02671.16 EIW86942.1 - 5.6e-38 128.3 6.9 3e-14 52.3 0.0 3.5 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EIW86942.1 - 6.6e-28 96.4 0.3 1.7e-27 95.1 0.2 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor Flu_M1_C PF08289.6 EIW86942.1 - 0.13 12.2 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain DUF4448 PF14610.1 EIW86943.1 - 0.00073 19.0 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 EIW86943.1 - 0.0063 16.2 0.0 0.017 14.8 0.0 1.7 1 0 0 1 1 1 1 TMEM154 protein family Vpu PF00558.14 EIW86943.1 - 0.0097 15.4 0.4 0.0097 15.4 0.3 1.6 2 0 0 2 2 2 1 Vpu protein WBP-1 PF11669.3 EIW86943.1 - 0.082 13.0 1.8 1.8 8.7 0.0 2.6 2 0 0 2 2 2 0 WW domain-binding protein 1 DUF4381 PF14316.1 EIW86943.1 - 0.093 12.8 1.6 0.19 11.8 0.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4381) DUF1049 PF06305.6 EIW86943.1 - 0.13 11.7 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) CD34_antigen PF06365.7 EIW86943.1 - 0.14 11.7 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family Ctr PF04145.10 EIW86943.1 - 0.85 9.6 3.2 4 7.4 2.1 2.3 1 1 0 1 1 1 0 Ctr copper transporter family HEAT_2 PF13646.1 EIW86944.1 - 0.0011 19.1 0.1 0.42 10.9 0.0 3.6 3 1 1 4 4 4 1 HEAT repeats Arm PF00514.18 EIW86944.1 - 0.003 17.3 4.0 0.0046 16.7 0.0 3.5 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 EIW86944.1 - 0.052 13.2 0.3 0.48 10.0 0.0 2.5 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis HEAT_EZ PF13513.1 EIW86944.1 - 3.5 8.2 5.4 4 8.0 0.1 4.0 5 1 1 6 6 6 0 HEAT-like repeat NAD_binding_2 PF03446.10 EIW86945.1 - 9.6e-22 77.5 0.0 1.5e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EIW86945.1 - 9.8e-09 35.3 0.4 2.2e-08 34.2 0.3 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.15 EIW86945.1 - 2.9e-05 24.1 0.0 5.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.10 EIW86945.1 - 0.0032 16.2 0.0 0.0059 15.4 0.0 1.4 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 EIW86945.1 - 0.016 15.6 0.0 0.042 14.2 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 EIW86945.1 - 0.025 14.8 0.0 4.8 7.5 0.0 2.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Pkinase PF00069.20 EIW86946.1 - 8e-38 130.0 0.0 1.2e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW86946.1 - 5.1e-28 97.8 0.0 7e-28 97.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW86946.1 - 0.00016 21.5 0.0 0.67 9.6 0.0 3.0 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW86946.1 - 0.096 11.6 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Exo5 PF09810.4 EIW86947.1 - 9.4e-64 215.6 0.0 7.7e-54 183.0 0.0 3.0 2 1 0 2 2 2 2 Exonuclease V - a 5' deoxyribonuclease PDDEXK_1 PF12705.2 EIW86947.1 - 0.0012 18.3 3.1 0.01 15.2 2.2 2.5 1 1 0 1 1 1 1 PD-(D/E)XK nuclease superfamily BRCA2 PF00634.13 EIW86947.1 - 0.15 11.3 0.1 0.33 10.2 0.1 1.5 1 0 0 1 1 1 0 BRCA2 repeat HA2 PF04408.18 EIW86949.1 - 3.1e-23 81.7 0.0 9.7e-23 80.1 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EIW86949.1 - 5.9e-17 61.5 0.0 1.8e-16 60.0 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EIW86949.1 - 3e-10 39.8 0.0 1.7e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EIW86949.1 - 1.5e-09 37.6 2.4 8.6e-09 35.1 0.3 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EIW86949.1 - 2.3e-05 24.5 2.9 9.6e-05 22.5 0.1 3.0 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EIW86949.1 - 0.0048 16.6 0.5 0.026 14.2 0.0 2.2 2 0 0 2 2 2 1 Archaeal ATPase Zeta_toxin PF06414.7 EIW86949.1 - 0.0052 15.9 0.2 0.15 11.1 0.0 2.5 1 1 1 2 2 2 1 Zeta toxin AAA_14 PF13173.1 EIW86949.1 - 0.027 14.3 0.1 1.5 8.7 0.0 3.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EIW86949.1 - 0.042 14.1 0.0 0.12 12.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter PhoH PF02562.11 EIW86949.1 - 0.052 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.1 EIW86949.1 - 0.054 13.2 0.2 0.17 11.6 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 EIW86949.1 - 0.056 12.3 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 EIW86949.1 - 0.087 11.9 0.0 0.21 10.6 0.0 1.6 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 EIW86949.1 - 0.092 12.3 0.1 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 NACHT domain OB_NTP_bind PF07717.11 EIW86950.1 - 4.2e-29 100.6 0.0 9.1e-29 99.5 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EIW86950.1 - 1.7e-28 98.6 0.1 4.7e-28 97.2 0.1 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EIW86950.1 - 2.6e-12 46.4 0.0 8.2e-12 44.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 EIW86950.1 - 1.7e-07 31.2 0.6 7.5e-07 29.1 0.1 2.2 2 0 0 2 2 2 1 S1 RNA binding domain DEAD PF00270.24 EIW86950.1 - 6.9e-06 25.6 0.0 1.5e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EIW86950.1 - 0.00043 19.2 0.0 0.001 18.0 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EIW86950.1 - 0.0024 18.0 0.2 0.011 15.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EIW86950.1 - 0.0055 16.4 0.1 0.016 14.9 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain Zot PF05707.7 EIW86950.1 - 0.043 13.2 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_25 PF13481.1 EIW86950.1 - 0.05 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EIW86950.1 - 0.071 13.4 3.5 1.5 9.0 0.1 3.6 3 1 0 3 3 3 0 ABC transporter DUF2075 PF09848.4 EIW86950.1 - 0.073 12.0 0.0 0.2 10.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Exo_endo_phos PF03372.18 EIW86951.1 - 1.8e-24 87.0 0.0 2.5e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Peptidase_M24 PF00557.19 EIW86952.1 - 5e-43 147.1 0.0 6.3e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 Histone PF00125.19 EIW86953.1 - 8.3e-14 51.4 0.1 1e-13 51.2 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIW86953.1 - 2.9e-05 24.1 0.0 3.8e-05 23.7 0.0 1.3 1 1 0 1 1 1 1 Kinetochore component CENP-S TAF PF02969.12 EIW86953.1 - 8.3e-05 22.4 0.1 0.00012 21.9 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.18 EIW86953.1 - 0.00072 19.5 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T PF15511.1 EIW86953.1 - 0.05 12.8 0.0 0.05 12.8 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EIW86953.1 - 0.1 12.4 0.0 0.13 12.0 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit RibD_C PF01872.12 EIW86954.1 - 6.2e-32 110.8 0.0 1.8e-31 109.3 0.0 1.6 1 1 0 1 1 1 1 RibD C-terminal domain RhoGEF PF00621.15 EIW86955.1 - 2.6e-11 43.7 0.0 2.1e-08 34.2 0.0 2.3 2 0 0 2 2 2 2 RhoGEF domain ZZ PF00569.12 EIW86956.1 - 7.1e-31 105.4 67.7 8e-10 38.1 4.2 5.5 5 0 0 5 5 5 5 Zinc finger, ZZ type WD40 PF00400.27 EIW86957.1 - 1.8e-79 259.0 25.0 1.2e-09 37.6 0.1 11.5 11 0 0 11 11 11 11 WD domain, G-beta repeat Utp13 PF08625.6 EIW86957.1 - 3.6e-41 140.1 0.0 6.2e-41 139.3 0.0 1.4 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nucleoporin_N PF08801.6 EIW86957.1 - 8.6e-08 31.3 2.4 0.37 9.4 0.0 5.5 1 1 2 5 5 5 4 Nup133 N terminal like Fork_head PF00250.13 EIW86958.1 - 3.2e-18 65.5 0.0 5.4e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Fork head domain AT_hook PF02178.14 EIW86958.1 - 0.032 13.8 2.3 0.032 13.8 1.6 3.3 2 0 0 2 2 2 0 AT hook motif DUF4200 PF13863.1 EIW86958.1 - 0.076 12.9 8.3 0.12 12.3 5.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) DivIVA PF05103.8 EIW86958.1 - 0.54 10.3 6.5 0.92 9.5 4.5 1.3 1 0 0 1 1 1 0 DivIVA protein Fungal_trans PF04082.13 EIW86959.1 - 7.2e-39 133.2 0.2 1e-38 132.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EIW86959.1 - 8.3e-05 22.4 6.6 0.00014 21.6 4.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NIPSNAP PF07978.8 EIW86960.1 - 3.4e-29 100.8 1.1 9e-26 89.8 0.2 2.2 2 0 0 2 2 2 2 NIPSNAP Glycos_transf_2 PF00535.21 EIW86961.1 - 0.004 16.8 0.0 0.0066 16.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 F5_F8_type_C PF00754.20 EIW86961.1 - 0.1 12.4 0.0 0.3 10.9 0.0 1.7 1 1 0 1 1 1 0 F5/8 type C domain Proteasome PF00227.21 EIW86962.1 - 3.7e-38 130.7 0.0 4.2e-38 130.5 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit MoaC PF01967.16 EIW86963.1 - 4.1e-40 136.5 0.9 1.6e-39 134.6 0.7 1.9 1 1 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 EIW86963.1 - 7.9e-37 125.8 0.0 1.5e-36 124.8 0.0 1.5 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EIW86963.1 - 9.1e-23 81.2 0.0 2.1e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EIW86963.1 - 3.8e-07 30.3 0.0 1.3e-05 25.3 0.0 2.6 3 0 0 3 3 3 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EIW86963.1 - 7.4e-06 25.9 0.0 3.9e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain PulG PF11773.3 EIW86963.1 - 0.021 14.5 0.0 17 5.2 0.0 3.3 3 0 0 3 3 3 0 Type II secretory pathway pseudopilin Mito_carr PF00153.22 EIW86965.1 - 9.8e-66 217.5 0.4 3.8e-24 84.2 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 EIW86965.1 - 2.6e-18 63.8 6.6 1.9e-06 26.7 0.1 6.6 8 0 0 8 8 8 2 EF hand EF-hand_7 PF13499.1 EIW86965.1 - 1.3e-16 60.4 3.9 1.4e-06 28.2 0.2 4.8 4 1 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 EIW86965.1 - 2e-16 58.3 6.5 4.2e-05 23.0 0.1 6.1 6 0 0 6 6 6 2 EF-hand domain EF-hand_8 PF13833.1 EIW86965.1 - 7.5e-12 44.6 5.6 0.0011 18.5 0.2 5.4 4 1 1 5 5 5 2 EF-hand domain pair EF-hand_5 PF13202.1 EIW86965.1 - 7.8e-08 31.3 10.8 3.5e-05 22.9 0.3 4.0 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.2 EIW86965.1 - 0.23 11.2 1.1 17 5.2 0.2 3.3 2 2 3 5 5 5 0 Cytoskeletal-regulatory complex EF hand Met_10 PF02475.11 EIW86966.1 - 1.8e-67 226.8 0.0 2.6e-67 226.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EIW86966.1 - 4.9e-07 29.7 0.1 2.9e-06 27.3 0.1 2.2 2 1 0 2 2 2 1 Methyltransferase domain MethyltransfD12 PF02086.10 EIW86966.1 - 0.00081 18.9 0.0 0.0018 17.7 0.0 1.5 1 0 0 1 1 1 1 D12 class N6 adenine-specific DNA methyltransferase Methyltransf_18 PF12847.2 EIW86966.1 - 0.0012 19.3 0.0 0.0028 18.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EIW86966.1 - 0.038 13.5 0.0 0.39 10.2 0.0 2.3 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase TatD_DNase PF01026.16 EIW86967.1 - 9.1e-22 77.4 0.0 1.4e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase V-SNARE_C PF12352.3 EIW86968.1 - 1.8e-16 59.9 1.1 1.8e-16 59.9 0.8 2.8 4 0 0 4 4 3 1 Snare region anchored in the vesicle membrane C-terminus Occludin_ELL PF07303.8 EIW86968.1 - 8.4e-05 23.2 1.1 0.014 16.1 1.1 3.2 2 1 1 3 3 3 1 Occludin homology domain Laminin_I PF06008.9 EIW86968.1 - 0.00024 20.5 0.9 0.00039 19.8 0.6 1.4 1 0 0 1 1 1 1 Laminin Domain I ADIP PF11559.3 EIW86968.1 - 0.0034 17.3 1.8 0.0034 17.3 1.3 2.2 2 2 0 2 2 2 1 Afadin- and alpha -actinin-Binding V_ATPase_I PF01496.14 EIW86968.1 - 0.013 13.3 0.3 0.014 13.2 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_13 PF13166.1 EIW86968.1 - 0.025 13.0 0.2 0.029 12.8 0.1 1.2 1 0 0 1 1 1 0 AAA domain Rho_Binding PF08912.6 EIW86968.1 - 0.035 14.4 1.7 0.12 12.6 0.6 2.3 2 1 1 3 3 3 0 Rho Binding zf-DNA_Pol PF08996.5 EIW86968.1 - 0.052 12.8 0.4 0.15 11.3 0.1 1.8 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger APG6 PF04111.7 EIW86968.1 - 0.069 12.1 2.3 0.11 11.4 1.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1476 PF07345.6 EIW86968.1 - 0.091 13.0 1.5 0.13 12.4 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1476) OmpH PF03938.9 EIW86968.1 - 0.16 11.9 1.1 0.21 11.5 0.7 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Syntaxin PF00804.20 EIW86968.1 - 0.16 12.1 1.0 0.36 11.0 0.7 1.8 1 1 0 1 1 1 0 Syntaxin WXG100 PF06013.7 EIW86968.1 - 0.19 11.7 1.7 8.4 6.4 0.0 3.1 2 2 1 3 3 3 0 Proteins of 100 residues with WXG PEP-utilisers_N PF05524.8 EIW86968.1 - 0.21 11.3 2.1 0.48 10.2 1.4 1.7 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Cep57_MT_bd PF06657.8 EIW86968.1 - 0.32 10.9 2.5 3.7 7.5 0.7 2.6 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 THOC7 PF05615.8 EIW86968.1 - 0.37 11.0 4.3 2.6 8.3 0.2 2.5 2 1 0 2 2 2 0 Tho complex subunit 7 CorA PF01544.13 EIW86968.1 - 0.51 9.3 3.7 1.2 8.0 0.2 2.2 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein Sec8_exocyst PF04048.9 EIW86968.1 - 0.7 9.5 3.2 9 5.9 0.5 3.1 1 1 0 2 2 2 0 Sec8 exocyst complex component specific domain AATF-Che1 PF13339.1 EIW86968.1 - 0.89 9.7 5.4 0.96 9.6 2.3 1.9 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor FlgN PF05130.7 EIW86968.1 - 0.89 9.7 4.4 0.81 9.9 1.0 2.1 1 1 0 1 1 1 0 FlgN protein Tropomyosin_1 PF12718.2 EIW86968.1 - 1.1 9.1 6.1 0.46 10.3 2.1 1.9 1 1 1 2 2 2 0 Tropomyosin like Lgl_C PF08596.5 EIW86969.1 - 4.4e-39 134.0 0.0 1.1e-38 132.7 0.0 1.6 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EIW86969.1 - 1.3e-06 28.0 0.0 0.0036 17.1 0.0 4.3 3 0 0 3 3 3 2 WD domain, G-beta repeat Hira PF07569.6 EIW86969.1 - 0.033 13.3 0.4 0.34 10.0 0.0 2.7 3 1 1 4 4 4 0 TUP1-like enhancer of split FliG_C PF01706.11 EIW86969.1 - 0.19 11.6 0.2 0.56 10.1 0.1 1.8 2 0 0 2 2 2 0 FliG C-terminal domain IncA PF04156.9 EIW86970.1 - 0.26 10.8 63.7 0.072 12.6 12.1 4.0 1 1 2 3 3 3 0 IncA protein Feld-I_B PF09252.5 EIW86970.1 - 0.64 9.9 4.0 1.5 8.7 0.1 2.7 2 0 0 2 2 2 0 Allergen Fel d I-B chain Fez1 PF06818.10 EIW86970.1 - 2.6 8.0 49.8 0.73 9.8 11.1 2.4 2 1 0 2 2 2 0 Fez1 Myosin_tail_1 PF01576.14 EIW86970.1 - 6.9 4.2 62.3 0.006 14.3 4.9 3.9 2 2 2 4 4 4 0 Myosin tail DAO PF01266.19 EIW86971.1 - 1.3e-16 60.4 0.0 2.5e-16 59.5 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW86971.1 - 0.025 14.5 0.0 0.052 13.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EIW86971.1 - 0.08 12.8 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EIW86971.1 - 0.12 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family DUF89 PF01937.14 EIW86973.1 - 2.9e-106 355.2 0.1 3.6e-106 354.9 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Asp PF00026.18 EIW86974.1 - 1.2e-51 175.9 16.6 2.6e-51 174.7 11.5 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EIW86974.1 - 4.1e-07 30.0 5.9 4.5e-05 23.4 2.5 3.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EIW86974.1 - 0.0001 22.7 8.2 0.00016 22.0 0.9 2.9 3 0 0 3 3 3 1 Aspartyl protease TAXi_C PF14541.1 EIW86974.1 - 0.095 12.2 0.3 2 7.9 0.2 2.4 1 1 0 1 1 1 0 Xylanase inhibitor C-terminal zf-RING_2 PF13639.1 EIW86975.1 - 8.1e-13 47.9 5.1 8.1e-13 47.9 3.5 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EIW86975.1 - 2.9e-11 43.2 1.0 2.9e-11 43.2 0.7 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EIW86975.1 - 3.2e-07 29.9 5.0 3.2e-07 29.9 3.4 2.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW86975.1 - 6.6e-07 28.9 3.1 6.6e-07 28.9 2.1 2.2 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EIW86975.1 - 6.9e-07 29.1 1.9 6.9e-07 29.1 1.3 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EIW86975.1 - 1.5e-06 27.7 2.1 1.5e-06 27.7 1.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EIW86975.1 - 5.4e-06 26.1 0.3 1.3e-05 24.8 0.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_3 PF14369.1 EIW86975.1 - 1.6e-05 24.8 4.3 2.2e-05 24.3 1.3 2.3 2 0 0 2 2 2 1 zinc-finger FANCL_C PF11793.3 EIW86975.1 - 0.037 13.9 3.8 0.16 11.9 2.6 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EIW86975.1 - 0.28 10.9 4.1 0.34 10.6 1.5 2.1 1 1 1 2 2 2 0 RING-type zinc-finger FYVE_2 PF02318.11 EIW86975.1 - 0.31 10.9 1.0 1.7 8.5 0.1 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger PHD PF00628.24 EIW86975.1 - 3.3 7.4 13.9 0.5 10.0 2.2 2.7 3 0 0 3 3 3 0 PHD-finger Prok-RING_1 PF14446.1 EIW86975.1 - 9.1 6.1 13.3 0.49 10.1 3.3 2.9 2 2 1 4 4 4 0 Prokaryotic RING finger family 1 ABC_tran PF00005.22 EIW86976.1 - 1.6e-46 157.9 0.0 1.3e-27 96.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EIW86976.1 - 2.8e-44 151.5 15.2 4.2e-25 88.6 1.1 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EIW86976.1 - 4.5e-11 42.3 1.4 0.00027 20.2 0.0 4.2 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EIW86976.1 - 4.1e-07 29.5 0.0 0.034 13.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EIW86976.1 - 4.2e-07 29.3 1.7 0.013 14.9 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF87 PF01935.12 EIW86976.1 - 4.3e-07 29.9 1.3 0.00046 20.0 0.2 2.3 2 0 0 2 2 2 2 Domain of unknown function DUF87 AAA_21 PF13304.1 EIW86976.1 - 1.4e-06 28.4 1.7 0.77 9.6 0.0 4.6 4 0 0 4 4 4 2 AAA domain T2SE PF00437.15 EIW86976.1 - 1.4e-06 27.4 0.5 0.021 13.7 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 EIW86976.1 - 3.2e-05 23.5 0.0 0.15 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain AAA_17 PF13207.1 EIW86976.1 - 6.1e-05 23.8 0.2 0.043 14.6 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.1 EIW86976.1 - 0.00012 22.5 0.1 0.15 12.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 EIW86976.1 - 0.00018 21.3 0.4 0.7 9.7 0.0 2.5 2 0 0 2 2 2 2 Dynamin family AAA_16 PF13191.1 EIW86976.1 - 0.00061 19.8 0.5 1.4 8.8 0.1 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.1 EIW86976.1 - 0.00063 20.0 0.3 0.33 11.2 0.1 2.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EIW86976.1 - 0.00071 18.7 0.6 0.39 9.7 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin FtsK_SpoIIIE PF01580.13 EIW86976.1 - 0.00085 18.8 0.1 0.16 11.3 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EIW86976.1 - 0.0009 19.1 0.0 0.13 12.2 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EIW86976.1 - 0.0012 18.9 0.7 1.2 9.3 0.2 3.2 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EIW86976.1 - 0.0019 17.8 0.1 0.17 11.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 EIW86976.1 - 0.0019 18.6 1.7 0.4 11.1 0.1 2.9 3 0 0 3 3 2 1 Miro-like protein AAA_33 PF13671.1 EIW86976.1 - 0.0024 17.7 0.6 0.61 9.9 0.1 2.8 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EIW86976.1 - 0.006 16.2 0.3 2 8.0 0.0 2.6 2 0 0 2 2 2 1 NACHT domain MobB PF03205.9 EIW86976.1 - 0.0064 16.2 0.6 0.16 11.7 0.0 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EIW86976.1 - 0.0078 15.7 0.6 0.8 9.1 0.0 2.3 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein DUF258 PF03193.11 EIW86976.1 - 0.026 13.7 0.1 4 6.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA PF00004.24 EIW86976.1 - 0.027 14.6 0.3 10 6.3 0.0 3.5 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EIW86976.1 - 0.043 13.9 0.1 5.2 7.2 0.0 2.5 2 0 0 2 2 2 0 RNA helicase TrwB_AAD_bind PF10412.4 EIW86976.1 - 0.043 12.4 1.1 0.77 8.3 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Sigma54_activat PF00158.21 EIW86976.1 - 0.049 13.1 0.0 0.47 9.9 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain DEAD PF00270.24 EIW86976.1 - 0.052 13.0 0.2 17 4.8 0.1 2.8 2 1 0 2 2 2 0 DEAD/DEAH box helicase AAA_19 PF13245.1 EIW86976.1 - 0.087 12.5 1.6 1.4 8.7 0.0 2.9 3 0 0 3 3 2 0 Part of AAA domain Adeno_IVa2 PF02456.10 EIW86976.1 - 0.12 11.0 0.4 3.2 6.2 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein ArgK PF03308.11 EIW86976.1 - 0.12 11.1 1.3 0.14 10.8 0.1 1.6 2 0 0 2 2 2 0 ArgK protein Lum_binding PF00677.12 EIW86977.1 - 8e-31 105.7 0.0 4.3e-14 52.1 0.0 3.1 2 1 0 2 2 2 2 Lumazine binding domain Myosin_head PF00063.16 EIW86978.1 - 7.9e-228 757.9 0.6 1.3e-227 757.1 0.4 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EIW86978.1 - 1.4e-45 155.0 0.0 2.4e-45 154.3 0.0 1.4 1 0 0 1 1 1 1 Myosin tail SH3_2 PF07653.12 EIW86978.1 - 3.8e-12 45.5 0.0 9.6e-12 44.2 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EIW86978.1 - 7.6e-12 44.6 0.2 2.5e-11 42.9 0.1 2.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EIW86978.1 - 4.4e-11 41.9 1.6 9.1e-11 40.9 1.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_3 PF08239.6 EIW86978.1 - 1.7e-05 24.9 0.6 4.3e-05 23.6 0.4 1.7 1 0 0 1 1 1 1 Bacterial SH3 domain AAA_22 PF13401.1 EIW86978.1 - 0.0074 16.4 0.0 0.021 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EIW86978.1 - 0.027 13.5 0.0 0.065 12.3 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Hpr_kinase_C PF07475.7 EIW86978.1 - 0.041 13.1 1.1 4.4 6.5 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_17 PF13207.1 EIW86978.1 - 0.06 14.1 0.0 0.19 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain SH3_4 PF06347.8 EIW86978.1 - 0.062 12.8 0.3 0.16 11.5 0.2 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain NACHT PF05729.7 EIW86978.1 - 0.094 12.3 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_16 PF13191.1 EIW86978.1 - 0.18 11.7 0.0 0.42 10.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain UNC45-central PF11701.3 EIW86979.1 - 1.7e-11 44.0 0.0 4.8e-11 42.5 0.0 1.8 1 0 0 1 1 1 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 EIW86979.1 - 3e-05 24.1 6.2 0.47 10.7 0.0 4.8 5 0 0 5 5 5 2 HEAT repeats Arm PF00514.18 EIW86979.1 - 0.075 12.8 1.3 4.3 7.3 0.1 4.1 4 1 0 4 4 4 0 Armadillo/beta-catenin-like repeat Gcd10p PF04189.8 EIW86980.1 - 1.4e-65 221.4 0.0 2.4e-64 217.3 0.0 2.0 1 1 0 1 1 1 1 Gcd10p family Nexin_C PF08628.7 EIW86981.1 - 1.5e-30 105.5 1.3 5.2e-30 103.8 0.0 2.7 3 0 0 3 3 3 1 Sorting nexin C terminal PXA PF02194.10 EIW86981.1 - 1e-28 100.1 0.1 1e-28 100.1 0.1 2.3 3 0 0 3 3 3 1 PXA domain PX PF00787.19 EIW86981.1 - 5.2e-18 64.8 0.3 5.3e-17 61.6 0.0 2.7 3 0 0 3 3 3 1 PX domain RGS PF00615.14 EIW86981.1 - 1.9e-10 40.8 0.1 7.6e-10 38.9 0.1 2.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain Isy1 PF06246.7 EIW86981.1 - 0.12 11.7 0.1 0.12 11.7 0.0 2.1 3 0 0 3 3 3 0 Isy1-like splicing family F-box-like PF12937.2 EIW86982.1 - 8.2e-06 25.4 0.1 1.5e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 F-box-like Mito_carr PF00153.22 EIW86983.1 - 2.6e-56 187.3 1.5 9.6e-20 70.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein OsmC PF02566.14 EIW86983.1 - 0.068 13.3 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 OsmC-like protein Taxilin PF09728.4 EIW86984.1 - 4e-14 52.4 31.8 5.4e-08 32.2 11.0 2.6 2 2 0 2 2 2 2 Myosin-like coiled-coil protein Rad60-SLD PF11976.3 EIW86984.1 - 7.6e-06 25.5 1.2 0.0042 16.7 0.0 3.3 4 0 0 4 4 4 2 Ubiquitin-2 like Rad60 SUMO-like DUF3292 PF11696.3 EIW86984.1 - 0.34 8.7 4.6 0.63 7.8 3.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) DUF2252 PF10009.4 EIW86984.1 - 0.87 8.4 16.7 0.12 11.2 6.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) CorA PF01544.13 EIW86984.1 - 3.3 6.6 15.2 2.8 6.8 1.0 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein UDPGP PF01704.13 EIW86985.1 - 3.2e-56 190.6 0.0 4.2e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EIW86985.1 - 0.012 15.6 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 MobA-like NTP transferase domain Cellulase PF00150.13 EIW86986.1 - 1.2e-09 37.8 0.8 2.3e-09 36.8 0.6 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Cellulase PF00150.13 EIW86987.1 - 5.5e-12 45.4 0.3 5.5e-12 45.4 0.2 1.7 3 0 0 3 3 3 1 Cellulase (glycosyl hydrolase family 5) Peptidase_M16 PF00675.15 EIW86988.1 - 1e-39 135.6 0.0 1.6e-39 135.0 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EIW86988.1 - 1.4e-29 103.1 0.0 6.3e-29 100.9 0.0 2.1 1 1 0 1 1 1 1 Peptidase M16 inactive domain Hairy_orange PF07527.8 EIW86988.1 - 0.11 12.2 0.0 7.6 6.3 0.1 2.9 2 0 0 2 2 2 0 Hairy Orange SAP30_Sin3_bdg PF13867.1 EIW86988.1 - 0.15 11.9 0.1 3.4 7.6 0.0 2.5 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 EF_TS PF00889.14 EIW86989.1 - 2.6e-24 85.7 0.0 2.8e-20 72.5 0.0 2.2 1 1 1 2 2 2 2 Elongation factor TS UBA PF00627.26 EIW86989.1 - 1.3e-05 24.8 0.1 6.8e-05 22.5 0.0 2.3 2 0 0 2 2 2 1 UBA/TS-N domain AIRS PF00586.19 EIW86989.1 - 0.075 13.2 0.3 0.3 11.3 0.0 2.2 1 1 2 3 3 3 0 AIR synthase related protein, N-terminal domain Gar1 PF04410.9 EIW86990.1 - 4.1e-30 104.2 0.0 4.1e-30 104.2 0.0 2.5 3 0 0 3 3 3 1 Gar1/Naf1 RNA binding region Ribonuclease_T2 PF00445.13 EIW86991.1 - 2.2e-42 144.8 0.1 3e-42 144.4 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family ACT_7 PF13840.1 EIW86992.1 - 1.5e-14 53.2 0.0 2.3e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 ACT domain SAS4 PF15460.1 EIW86993.1 - 3.3e-06 26.8 1.6 3.3e-06 26.8 1.1 1.7 2 0 0 2 2 2 1 Something about silencing, SAS, complex subunit 4 PEHE PF15275.1 EIW86993.1 - 3.7e-06 27.3 0.9 3.7e-06 27.3 0.6 3.3 4 0 0 4 4 4 1 PEHE domain Sugar_tr PF00083.19 EIW86994.1 - 8.6e-115 383.8 29.3 1.1e-114 383.5 20.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW86994.1 - 8.5e-26 90.4 49.5 2.5e-19 69.2 13.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Spidroin_MaSp PF11260.3 EIW86995.1 - 0.071 13.1 0.4 0.091 12.8 0.3 1.2 1 0 0 1 1 1 0 Major ampullate spidroin 1 and 2 DUF3956 PF13104.1 EIW86995.1 - 0.1 12.1 0.2 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3956) zf-DHHC PF01529.15 EIW86996.1 - 1.9e-40 138.0 2.2 1.9e-40 138.0 1.5 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Transglut_core3 PF13471.1 EIW86996.1 - 0.055 13.2 1.9 0.12 12.1 1.3 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily Bromodomain PF00439.20 EIW86997.1 - 1.3e-20 73.0 0.1 2.1e-20 72.3 0.1 1.3 1 0 0 1 1 1 1 Bromodomain FA_desaturase PF00487.19 EIW86998.1 - 9.9e-06 25.1 17.9 0.00013 21.5 12.8 2.5 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EIW86998.1 - 7.6e-05 22.4 0.0 0.0002 21.1 0.0 1.7 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain UPF0220 PF05255.6 EIW86998.1 - 0.088 12.0 0.1 2 7.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0220) CutC PF03932.9 EIW86999.1 - 6.1e-35 120.3 0.0 7.9e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 CutC family F-box-like PF12937.2 EIW87000.1 - 0.014 15.0 0.0 0.027 14.1 0.0 1.5 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 EIW87000.1 - 0.016 14.8 1.1 0.023 14.3 0.1 1.8 2 0 0 2 2 2 0 F-box domain RPEL PF02755.10 EIW87000.1 - 0.034 13.4 0.0 0.076 12.3 0.0 1.5 1 0 0 1 1 1 0 RPEL repeat Glyco_transf_22 PF03901.12 EIW87002.1 - 2.5e-82 277.1 13.0 6.7e-82 275.7 9.0 1.7 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family DUF4181 PF13789.1 EIW87002.1 - 0.071 13.0 1.5 0.25 11.2 1.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) Thioredoxin PF00085.15 EIW87004.1 - 4.5e-28 96.9 0.0 5.8e-28 96.6 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EIW87004.1 - 4.6e-08 33.0 0.0 1.2e-05 25.3 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EIW87004.1 - 1.2e-07 31.8 0.1 6.7e-07 29.5 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_9 PF14595.1 EIW87004.1 - 5.8e-05 22.6 0.0 7.5e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 EIW87004.1 - 7.4e-05 22.4 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.1 EIW87004.1 - 0.0001 22.2 0.1 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like TraF PF13728.1 EIW87004.1 - 0.0042 16.6 0.0 0.0061 16.0 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein DUF2847 PF11009.3 EIW87004.1 - 0.0046 16.5 0.0 0.0076 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2847) Redoxin PF08534.5 EIW87004.1 - 0.0047 16.4 0.2 0.009 15.5 0.1 1.6 1 1 0 1 1 1 1 Redoxin DUF953 PF06110.6 EIW87004.1 - 0.051 13.0 0.0 0.14 11.5 0.0 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_4 PF13462.1 EIW87004.1 - 0.057 13.4 0.3 0.21 11.5 0.1 1.8 1 1 1 2 2 2 0 Thioredoxin DIM1 PF02966.11 EIW87004.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Mitosis protein DIM1 Thioredoxin_6 PF13848.1 EIW87004.1 - 0.14 11.9 0.0 0.18 11.5 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain dsrm PF00035.20 EIW87005.1 - 7.9e-09 35.9 0.0 1.5e-08 35.0 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonucleas_3_3 PF14622.1 EIW87005.1 - 2.3e-07 30.8 0.0 3.3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EIW87005.1 - 0.0058 17.0 0.0 0.018 15.4 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease III domain DUF3824 PF12868.2 EIW87005.1 - 0.014 16.3 3.3 0.022 15.7 2.3 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) I-set PF07679.11 EIW87006.1 - 0.011 15.5 0.5 1 9.2 0.0 4.0 5 0 0 5 5 5 0 Immunoglobulin I-set domain PBP1_TM PF14812.1 EIW87006.1 - 0.51 10.6 5.1 1.2 9.4 3.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Inhibitor_I53 PF11714.3 EIW87006.1 - 0.72 9.8 4.8 2.2 8.2 3.3 1.8 1 0 0 1 1 1 0 Thrombin inhibitor Madanin Pyrophosphatase PF00719.14 EIW87007.1 - 1.7e-54 183.5 0.2 2.4e-54 182.9 0.1 1.2 1 0 0 1 1 1 1 Inorganic pyrophosphatase Spc97_Spc98 PF04130.8 EIW87008.1 - 5.1e-64 216.5 1.7 7.3e-64 216.0 1.2 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family RabGAP-TBC PF00566.13 EIW87009.1 - 8.6e-30 103.8 0.0 1.4e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Transthyretin PF00576.16 EIW87010.1 - 4.4e-37 126.3 0.1 1.2e-36 125.0 0.1 1.6 1 1 0 1 1 1 1 HIUase/Transthyretin family CarboxypepD_reg PF13620.1 EIW87010.1 - 0.0037 17.2 0.0 0.02 14.9 0.0 2.0 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.4 EIW87010.1 - 0.087 12.8 0.0 0.17 11.8 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4198) DUF2606 PF10794.4 EIW87010.1 - 0.1 12.0 0.0 0.16 11.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2606) MG1 PF11974.3 EIW87010.1 - 0.13 12.8 0.0 0.16 12.5 0.0 1.2 1 0 0 1 1 1 0 Alpha-2-macroglobulin MG1 domain UQ_con PF00179.21 EIW87011.1 - 3.7e-40 136.5 0.3 4.8e-40 136.2 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EIW87011.1 - 0.028 14.1 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 UEV domain RWD PF05773.17 EIW87011.1 - 0.052 13.4 0.4 0.067 13.0 0.2 1.4 1 1 0 1 1 1 0 RWD domain DIOX_N PF14226.1 EIW87012.1 - 0.00026 21.5 0.1 0.00074 20.0 0.0 1.9 1 1 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIW87012.1 - 0.024 14.9 0.0 0.043 14.1 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Chorismate_bind PF00425.13 EIW87013.1 - 5.6e-57 193.0 0.0 1.9e-56 191.2 0.0 1.8 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 EIW87013.1 - 8.3e-35 119.9 0.0 1.2e-34 119.4 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EIW87013.1 - 4.7e-14 52.5 0.0 1.2e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EIW87013.1 - 5.3e-06 26.0 0.7 1.5e-05 24.5 0.5 1.7 1 1 0 1 1 1 1 Peptidase C26 dCMP_cyt_deam_1 PF00383.17 EIW87015.1 - 2.4e-25 88.1 1.2 3.5e-25 87.6 0.8 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region AAA_17 PF13207.1 EIW87015.1 - 0.013 16.3 0.0 0.023 15.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain RNase_P_pop3 PF08228.6 EIW87016.1 - 0.0015 18.3 1.7 0.38 10.5 0.2 2.4 2 1 0 2 2 2 2 RNase P subunit Pop3 Amidase PF01425.16 EIW87017.1 - 7.6e-96 321.6 0.0 8.8e-96 321.4 0.0 1.0 1 0 0 1 1 1 1 Amidase E2F_TDP PF02319.15 EIW87017.1 - 0.15 11.6 0.1 0.31 10.6 0.0 1.4 1 0 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain Acetyltransf_10 PF13673.1 EIW87018.1 - 4.2e-07 30.0 0.0 7.7e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EIW87018.1 - 1.6e-06 27.7 0.0 3.4e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EIW87018.1 - 3.8e-06 26.9 0.0 8.9e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EIW87018.1 - 1.2e-05 25.2 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family YccV-like PF08755.6 EIW87019.1 - 1.4e-21 76.2 0.1 3.6e-21 74.9 0.0 1.7 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.1 EIW87019.1 - 7.2e-14 51.5 0.0 1.7e-13 50.3 0.0 1.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily F-box-like PF12937.2 EIW87019.1 - 0.0014 18.3 0.2 0.0032 17.1 0.1 1.6 1 0 0 1 1 1 1 F-box-like AATase PF07247.7 EIW87020.1 - 0.04 12.4 0.1 1.8 7.0 0.0 2.1 2 0 0 2 2 2 0 Alcohol acetyltransferase Tri3 PF07428.6 EIW87020.1 - 0.14 10.8 0.0 0.21 10.2 0.0 1.2 1 0 0 1 1 1 0 15-O-acetyltransferase Tri3 TPT PF03151.11 EIW87021.1 - 6.9e-07 29.0 12.1 6.9e-07 29.0 8.4 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EIW87021.1 - 0.0008 19.4 10.4 0.0008 19.4 7.2 2.7 2 2 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EIW87021.1 - 0.015 14.2 16.0 0.042 12.7 1.7 2.2 1 1 0 2 2 2 0 UAA transporter family COPI_assoc PF08507.5 EIW87021.1 - 0.017 14.7 1.3 0.017 14.7 0.9 3.4 2 1 1 3 3 3 0 COPI associated protein Coq4 PF05019.8 EIW87021.1 - 0.059 12.2 0.0 0.1 11.5 0.0 1.3 1 0 0 1 1 1 0 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 ApbA_C PF08546.6 EIW87022.1 - 1.6e-33 115.3 0.0 3.6e-33 114.2 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EIW87022.1 - 3.1e-28 98.1 0.3 4.4e-28 97.6 0.2 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GFO_IDH_MocA PF01408.17 EIW87022.1 - 0.021 15.3 0.4 0.06 13.8 0.3 1.8 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_Gly3P_dh_N PF01210.18 EIW87022.1 - 0.081 12.6 0.1 0.26 11.0 0.0 1.9 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 EIW87022.1 - 0.12 12.4 0.5 0.69 9.9 0.4 2.1 1 1 0 1 1 1 0 TrkA-N domain Aldo_ket_red PF00248.16 EIW87023.1 - 3e-44 150.9 0.0 3.5e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family PB1 PF00564.19 EIW87024.1 - 2.1e-08 33.7 0.0 5.3e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 PB1 domain F-box-like PF12937.2 EIW87025.1 - 2.7e-07 30.2 2.8 1.2e-06 28.0 1.0 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIW87025.1 - 0.025 14.2 0.8 0.14 11.8 0.8 2.2 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.2 EIW87025.1 - 1.4 8.6 4.5 2.2 7.9 0.1 3.5 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Homeobox PF00046.24 EIW87026.1 - 3.4e-14 52.2 0.4 6.8e-14 51.2 0.2 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIW87026.1 - 0.00063 19.3 0.0 0.0016 18.1 0.0 1.7 1 0 0 1 1 1 1 Homeobox KN domain DUF4482 PF14818.1 EIW87026.1 - 1 10.0 4.6 0.67 10.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4482) WD40 PF00400.27 EIW87027.1 - 6.5e-21 73.3 10.7 9.9e-06 25.2 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat Methyltransf_11 PF08241.7 EIW87028.1 - 5.9e-11 42.7 0.0 1.4e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW87028.1 - 3.4e-09 36.6 0.0 6.7e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW87028.1 - 1.5e-08 34.0 0.0 2.3e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EIW87028.1 - 1.5e-08 35.2 0.0 6.5e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW87028.1 - 2.5e-08 34.2 0.0 4.7e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIW87028.1 - 0.00018 20.6 0.0 0.00038 19.5 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 EIW87028.1 - 0.00045 20.6 0.0 0.0017 18.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW87028.1 - 0.00057 19.4 0.0 0.0017 17.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW87028.1 - 0.00073 19.5 0.0 0.0021 18.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EIW87028.1 - 0.01 15.0 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_29 PF03141.11 EIW87028.1 - 0.019 13.3 0.0 0.034 12.4 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase UPF0020 PF01170.13 EIW87028.1 - 0.066 12.7 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 MTS PF05175.9 EIW87028.1 - 0.071 12.4 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain RAP1 PF07218.6 EIW87028.1 - 0.17 9.9 1.6 0.23 9.5 1.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Pyr_redox_2 PF07992.9 EIW87029.1 - 3e-16 59.8 0.0 5.7e-16 58.9 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EIW87029.1 - 6.6e-15 55.2 3.1 9.3e-12 45.1 0.1 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EIW87029.1 - 3.7e-10 40.2 0.1 1.1e-06 28.8 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EIW87029.1 - 4.1e-09 35.8 0.1 0.011 14.6 0.0 3.1 2 1 1 3 3 3 3 Lycopene cyclase protein DAO PF01266.19 EIW87029.1 - 1.2e-07 30.9 2.4 0.074 11.9 0.1 3.4 3 0 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EIW87029.1 - 5.8e-07 29.4 0.1 0.014 15.4 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EIW87029.1 - 1.8e-06 27.1 0.0 0.0015 17.5 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.15 EIW87029.1 - 4.2e-05 23.6 0.2 0.13 12.4 0.0 2.3 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EIW87029.1 - 0.00011 21.9 0.4 0.091 12.5 0.0 3.5 3 1 1 4 4 4 1 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 EIW87029.1 - 0.00017 21.3 0.0 0.14 11.8 0.0 2.3 2 0 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 EIW87029.1 - 0.00022 21.1 0.2 0.1 12.6 0.0 2.4 2 0 0 2 2 2 1 TrkA-N domain AlaDh_PNT_C PF01262.16 EIW87029.1 - 0.00023 20.7 0.2 0.005 16.4 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 EIW87029.1 - 0.00065 19.1 0.2 0.89 8.9 0.0 2.5 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 EIW87029.1 - 0.0027 17.9 0.2 0.15 12.3 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.12 EIW87029.1 - 0.0077 15.3 0.4 0.86 8.6 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.9 EIW87029.1 - 0.0082 14.8 0.5 0.059 12.0 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.17 EIW87029.1 - 0.011 14.6 6.7 0.59 8.9 0.0 3.9 4 1 1 5 5 5 0 Glucose inhibited division protein A DUF4147 PF13660.1 EIW87029.1 - 0.018 14.1 0.2 0.66 9.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4147) FAD_binding_3 PF01494.14 EIW87029.1 - 0.028 13.5 0.1 0.4 9.6 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Saccharop_dh PF03435.13 EIW87029.1 - 0.033 13.1 0.1 6.4 5.6 0.0 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase Malic_M PF03949.10 EIW87029.1 - 0.04 13.4 0.2 0.44 10.0 0.0 2.2 2 0 0 2 2 2 0 Malic enzyme, NAD binding domain Mqo PF06039.10 EIW87029.1 - 0.07 11.2 0.0 0.77 7.8 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) HI0933_like PF03486.9 EIW87029.1 - 0.1 11.0 3.0 1.6 7.1 0.0 3.4 3 2 1 5 5 5 0 HI0933-like protein IlvN PF07991.7 EIW87029.1 - 0.11 11.8 0.3 1.9 7.8 0.1 2.5 3 0 0 3 3 3 0 Acetohydroxy acid isomeroreductase, catalytic domain ThiF PF00899.16 EIW87029.1 - 0.12 12.2 0.9 9.2 6.0 0.1 2.5 2 0 0 2 2 2 0 ThiF family DUF3530 PF12048.3 EIW87029.1 - 0.23 10.4 1.1 0.58 9.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) MMR_HSR1 PF01926.18 EIW87030.1 - 3.1e-13 49.6 0.0 7.6e-13 48.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EIW87030.1 - 1.3e-06 27.7 0.0 5.4e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EIW87030.1 - 0.0018 18.1 0.9 0.058 13.2 0.1 2.8 2 1 1 3 3 3 1 Dynamin family DUF258 PF03193.11 EIW87030.1 - 0.0026 16.9 0.0 0.005 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EIW87030.1 - 0.0072 16.8 0.0 0.016 15.7 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Nop14 PF04147.7 EIW87030.1 - 8.7 4.1 6.1 13 3.5 4.2 1.1 1 0 0 1 1 1 0 Nop14-like family DUF605 PF04652.11 EIW87031.1 - 5.3e-73 246.6 34.7 2.5e-71 241.1 24.0 2.7 1 1 0 1 1 1 1 Vta1 like Arrestin_C PF02752.17 EIW87032.1 - 1.7e-05 24.9 0.0 5.6e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain zf-C2H2_4 PF13894.1 EIW87033.1 - 0.74 10.2 3.6 7.9 7.0 0.3 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger GDC-P PF02347.11 EIW87034.1 - 2.2e-181 603.2 0.3 1.6e-172 574.0 0.0 3.2 3 1 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.14 EIW87034.1 - 4.7e-06 25.5 0.2 0.00065 18.5 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 EIW87034.1 - 6.1e-06 25.5 0.1 1.1e-05 24.7 0.1 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase SecE PF00584.15 EIW87035.1 - 7.4e-14 51.0 0.0 8.7e-14 50.8 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex CbtB PF09489.5 EIW87035.1 - 0.13 12.1 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) Vps51 PF08700.6 EIW87036.1 - 4.1e-15 55.4 0.2 1.7e-14 53.3 0.1 2.1 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 EIW87036.1 - 0.91 9.4 5.7 8.6 6.2 0.2 2.7 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 OEP PF02321.13 EIW87036.1 - 3.6 7.1 11.1 0.24 10.9 0.5 2.7 3 0 0 3 3 3 0 Outer membrane efflux protein DUF1751 PF08551.5 EIW87037.1 - 1.9e-25 89.0 5.6 3.9e-25 88.0 3.9 1.5 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) DUF1754 PF08555.5 EIW87038.1 - 5.3e-15 55.8 8.4 5.3e-15 55.8 5.8 1.4 2 0 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) DUF4191 PF13829.1 EIW87038.1 - 0.0087 15.2 0.1 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4191) PP2C_C PF07830.8 EIW87038.1 - 0.051 13.6 0.6 0.27 11.3 0.0 2.3 3 0 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain DUF3827 PF12877.2 EIW87038.1 - 0.12 10.5 7.0 0.13 10.3 4.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) NinG PF05766.7 EIW87038.1 - 0.5 10.0 5.9 2.4 7.8 0.9 2.0 2 0 0 2 2 2 0 Bacteriophage Lambda NinG protein Peptidase_M3 PF01432.15 EIW87040.1 - 4.7e-121 405.0 0.0 5.9e-121 404.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Mating_C PF12737.2 EIW87041.1 - 3.5e-13 49.2 25.9 6.1e-12 45.1 14.5 3.1 2 1 0 2 2 2 1 C-terminal domain of homeodomain 1 Homeobox_KN PF05920.6 EIW87041.1 - 4.9e-11 42.1 0.7 1.2e-10 40.9 0.5 1.7 1 0 0 1 1 1 1 Homeobox KN domain Mating_N PF12731.2 EIW87041.1 - 0.00074 19.3 1.7 0.0015 18.3 1.2 1.5 1 0 0 1 1 1 1 Mating-type protein beta 1 Homeobox PF00046.24 EIW87041.1 - 0.1 12.2 0.0 0.29 10.7 0.0 1.8 1 0 0 1 1 1 0 Homeobox domain Homeobox PF00046.24 EIW87042.1 - 3.9e-15 55.1 0.1 8.9e-15 54.0 0.1 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIW87042.1 - 1.3e-09 37.6 1.8 1.1e-08 34.6 0.1 2.8 3 0 0 3 3 3 1 Homeobox KN domain Homez PF11569.3 EIW87042.1 - 0.002 17.1 0.0 0.0056 15.7 0.0 1.7 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez DUF883 PF05957.8 EIW87044.1 - 0.00019 21.7 2.4 0.15 12.4 0.1 2.2 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 EIW87044.1 - 0.00023 20.7 2.6 0.00085 18.8 1.8 1.7 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain ATP-synt_B PF00430.13 EIW87044.1 - 0.0018 18.0 5.8 0.0073 16.1 0.4 2.1 2 0 0 2 2 2 2 ATP synthase B/B' CF(0) DUF3250 PF11618.3 EIW87044.1 - 0.024 14.7 0.0 0.046 13.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3250) RAP1 PF07218.6 EIW87044.1 - 0.29 9.1 3.2 0.32 9.0 2.2 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Phasin_2 PF09361.5 EIW87044.1 - 0.37 10.8 8.9 0.099 12.6 1.4 2.2 2 0 0 2 2 2 0 Phasin protein Glyco_transf_8 PF01501.15 EIW87045.1 - 8.9e-33 113.6 0.0 1.3e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EIW87045.1 - 0.026 13.8 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Lung_7-TM_R PF06814.8 EIW87046.1 - 4.9e-59 199.6 19.0 7.1e-59 199.1 13.2 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor PX PF00787.19 EIW87047.1 - 5.6e-20 71.2 1.9 2e-19 69.4 1.2 1.9 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EIW87047.1 - 7.3e-06 25.4 3.9 0.0093 15.2 3.0 2.6 1 1 1 3 3 3 2 Vps5 C terminal like BAR PF03114.13 EIW87047.1 - 0.55 9.7 5.6 2.8 7.4 0.5 3.0 4 0 0 4 4 4 0 BAR domain RNA_pol_Rpb2_6 PF00562.23 EIW87048.1 - 1.6e-128 428.7 0.1 2.5e-128 428.0 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EIW87048.1 - 4.2e-69 231.5 0.0 6.5e-69 230.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EIW87048.1 - 2.3e-48 164.1 0.3 5.9e-48 162.8 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EIW87048.1 - 2.2e-29 101.5 0.0 5.4e-29 100.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EIW87048.1 - 1.3e-27 95.3 0.5 3.5e-27 93.9 0.4 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EIW87048.1 - 1.3e-23 82.4 0.1 3e-23 81.3 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EIW87048.1 - 1.5e-22 79.2 0.1 3.7e-22 78.0 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Fructosamin_kin PF03881.9 EIW87049.1 - 9.5e-66 221.6 0.0 1.1e-65 221.4 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EIW87049.1 - 6.9e-07 29.2 0.0 9.5e-07 28.7 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EIW87049.1 - 0.14 11.2 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Ecdysteroid kinase Oxidored_FMN PF00724.15 EIW87050.1 - 5.1e-68 229.5 0.0 7.5e-68 229.0 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family ABC1 PF03109.11 EIW87051.1 - 2.4e-21 75.8 0.0 6.6e-12 45.4 0.0 2.7 3 0 0 3 3 3 2 ABC1 family APH PF01636.18 EIW87051.1 - 0.02 14.6 0.1 0.4 10.3 0.0 2.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family NUT_C PF12882.2 EIW87052.1 - 0.047 13.3 0.0 0.098 12.2 0.0 1.6 1 0 0 1 1 1 0 NUT protein C terminal MFS_1 PF07690.11 EIW87053.1 - 2.3e-49 168.0 29.9 3.8e-46 157.4 14.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EIW87053.1 - 2e-15 56.3 6.9 2e-15 56.3 4.8 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EIW87053.1 - 1.8e-11 42.9 3.7 3.6e-11 41.9 2.6 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 EIW87053.1 - 5.5e-07 28.4 16.2 0.00032 19.2 1.4 3.2 2 1 1 3 3 3 2 Vacuole effluxer Atg22 like MFS_2 PF13347.1 EIW87053.1 - 2.2e-05 23.0 6.5 2.2e-05 23.0 4.5 3.1 2 1 2 4 4 4 1 MFS/sugar transport protein MFS_3 PF05977.8 EIW87053.1 - 0.00022 19.4 4.9 0.00022 19.4 3.4 1.8 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_1_like PF12832.2 EIW87053.1 - 0.0081 15.9 1.2 0.16 11.7 0.2 2.7 2 0 0 2 2 2 1 MFS_1 like family OATP PF03137.15 EIW87053.1 - 4.8 5.1 8.4 0.14 10.1 0.8 2.1 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family P5-ATPase PF12409.3 EIW87053.1 - 6.6 6.6 7.4 4.3 7.2 0.2 2.5 2 0 0 2 2 2 0 P5-type ATPase cation transporter 3Beta_HSD PF01073.14 EIW87054.1 - 2e-16 59.5 0.0 1.1e-07 30.8 0.0 2.1 1 1 1 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EIW87054.1 - 6.8e-15 55.5 0.9 7.3e-14 52.1 0.6 2.1 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW87054.1 - 6.6e-13 48.6 0.0 5.5e-12 45.6 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EIW87054.1 - 8e-13 47.9 0.1 5.1e-06 25.5 0.0 2.3 2 0 0 2 2 2 2 RmlD substrate binding domain TrkA_N PF02254.13 EIW87054.1 - 2.2e-06 27.6 0.0 4.7e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 EIW87054.1 - 1.8e-05 23.8 0.1 2.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 EIW87054.1 - 3.2e-05 23.2 0.0 4.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EIW87054.1 - 7.4e-05 21.7 0.1 0.0016 17.3 0.0 2.2 1 1 1 2 2 2 1 Male sterility protein NAD_Gly3P_dh_N PF01210.18 EIW87054.1 - 0.0064 16.2 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EIW87054.1 - 0.0067 15.8 0.1 0.017 14.5 0.0 1.6 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 EIW87054.1 - 0.0075 16.6 0.0 0.034 14.5 0.0 2.0 1 1 1 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 EIW87054.1 - 0.02 14.7 0.8 0.71 9.7 0.3 2.4 1 1 1 2 2 2 0 ThiF family Ldh_1_N PF00056.18 EIW87054.1 - 0.024 14.4 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EIW87054.1 - 0.031 13.9 0.0 0.054 13.1 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CWC25 PF12542.3 EIW87055.1 - 3e-26 91.7 1.0 3e-26 91.7 0.7 3.9 4 0 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EIW87055.1 - 1.8e-12 47.0 13.2 1.8e-12 47.0 9.1 4.8 3 1 1 4 4 4 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF1754 PF08555.5 EIW87055.1 - 0.0047 17.4 4.6 0.0047 17.4 3.2 3.7 3 1 0 3 3 3 1 Eukaryotic family of unknown function (DUF1754) CDK2AP PF09806.4 EIW87055.1 - 0.37 10.9 15.6 5.1 7.2 1.3 3.3 3 0 0 3 3 3 0 Cyclin-dependent kinase 2-associated protein Ion_trans PF00520.26 EIW87056.1 - 1e-06 28.1 1.6 1.7e-06 27.4 1.1 1.3 1 0 0 1 1 1 1 Ion transport protein ANTH PF07651.11 EIW87058.1 - 6.2e-71 238.3 0.0 6.2e-71 238.3 0.0 3.1 2 1 1 3 3 3 1 ANTH domain I_LWEQ PF01608.12 EIW87058.1 - 9.1e-63 210.7 8.1 9.1e-63 210.7 5.6 4.6 4 1 0 4 4 4 1 I/LWEQ domain ENTH PF01417.15 EIW87058.1 - 2.8e-05 23.9 0.1 0.00029 20.7 0.0 2.9 3 0 0 3 3 3 1 ENTH domain SURF1 PF02104.10 EIW87059.1 - 1.1e-57 195.3 0.0 1.4e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 SURF1 family APG6 PF04111.7 EIW87060.1 - 0.8 8.6 7.7 1.6 7.7 1.2 2.3 2 0 0 2 2 2 0 Autophagy protein Apg6 Myb_DNA-binding PF00249.26 EIW87062.1 - 2.6e-09 36.9 0.0 5.6e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EIW87062.1 - 0.00054 20.0 0.1 0.0011 19.0 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain NmrA PF05368.8 EIW87063.1 - 4.7e-26 91.4 0.0 6.4e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EIW87063.1 - 2.9e-09 37.1 0.4 6e-09 36.1 0.3 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EIW87063.1 - 3.3e-06 26.6 0.0 2.2e-05 24.0 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EIW87063.1 - 0.0018 18.2 0.9 0.0067 16.3 0.1 2.3 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EIW87063.1 - 0.0033 16.3 0.1 0.16 10.8 0.0 2.4 2 1 0 2 2 2 1 Male sterility protein KR PF08659.5 EIW87063.1 - 0.024 14.3 0.1 0.077 12.6 0.0 1.9 1 1 0 1 1 1 0 KR domain Ribonuclease_T2 PF00445.13 EIW87064.1 - 3.6e-33 114.7 0.1 5.6e-33 114.1 0.1 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family C6 PF01681.12 EIW87064.1 - 0.54 10.3 8.2 0.13 12.3 0.7 2.8 2 1 1 3 3 3 0 C6 domain SIR2 PF02146.12 EIW87065.1 - 3.6e-33 114.7 0.0 2.1e-20 73.2 0.0 2.2 2 0 0 2 2 2 2 Sir2 family Transposase_22 PF02994.9 EIW87065.1 - 0.015 13.8 1.9 0.018 13.5 0.0 2.0 3 0 0 3 3 3 0 L1 transposable element RNA_pol_Rpb6 PF01192.17 EIW87066.1 - 1.4e-23 82.3 0.3 2e-23 81.8 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb6 RRM_1 PF00076.17 EIW87067.1 - 4.7e-16 58.1 0.0 5.6e-10 38.7 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW87067.1 - 8.9e-13 48.0 0.0 1.5e-07 31.3 0.0 2.6 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW87067.1 - 6.6e-12 45.0 0.0 1.5e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NBP1 PF08537.5 EIW87067.1 - 0.11 11.6 2.1 0.24 10.5 1.5 1.5 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 Abhydrolase_6 PF12697.2 EIW87068.1 - 0.0069 16.2 0.2 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family ParA PF10609.4 EIW87070.1 - 2.1e-32 110.8 0.1 3.5e-32 110.1 0.1 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EIW87070.1 - 4.4e-14 52.3 0.0 7.4e-14 51.6 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EIW87070.1 - 4.6e-07 29.9 0.0 2.2e-05 24.4 0.0 2.5 2 1 1 3 3 3 1 AAA domain ArsA_ATPase PF02374.10 EIW87070.1 - 1.8e-06 27.2 0.2 6.5e-05 22.1 0.1 2.1 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 EIW87070.1 - 5.3e-05 22.4 0.1 0.0038 16.3 0.1 2.1 2 0 0 2 2 2 1 ATPase MipZ DUF258 PF03193.11 EIW87070.1 - 0.02 14.0 0.2 0.041 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EIW87070.1 - 0.022 14.1 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain YhjQ PF06564.7 EIW87070.1 - 0.023 14.0 0.1 0.038 13.3 0.0 1.3 1 1 0 1 1 1 0 YhjQ protein Zeta_toxin PF06414.7 EIW87070.1 - 0.063 12.3 0.0 0.2 10.7 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.17 EIW87070.1 - 0.084 12.3 0.0 2.5 7.4 0.0 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 EIW87070.1 - 0.09 12.9 0.0 0.23 11.6 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EIW87070.1 - 0.12 13.2 0.0 0.24 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rep_fac_C PF08542.6 EIW87071.1 - 3.4e-20 71.8 0.0 8.4e-20 70.5 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EIW87071.1 - 8e-12 45.1 0.0 1.1e-09 38.1 0.0 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.24 EIW87071.1 - 9e-12 45.3 0.0 1.4e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EIW87071.1 - 2.3e-07 30.7 0.0 4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EIW87071.1 - 2.2e-06 27.8 0.0 4.1e-05 23.6 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EIW87071.1 - 5.3e-06 26.6 0.0 0.0045 17.1 0.0 2.6 1 1 1 2 2 2 2 AAA domain Rad17 PF03215.10 EIW87071.1 - 7.9e-06 24.8 0.1 0.018 13.7 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_3 PF07726.6 EIW87071.1 - 6.1e-05 22.6 0.0 0.00015 21.3 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIW87071.1 - 6.1e-05 22.1 0.0 0.00014 20.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Viral_helicase1 PF01443.13 EIW87071.1 - 0.00033 20.2 0.0 0.00052 19.6 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase DNA_pol3_delta PF06144.8 EIW87071.1 - 0.00076 19.0 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_10 PF12846.2 EIW87071.1 - 0.001 18.5 0.0 0.18 11.1 0.0 2.5 2 1 0 3 3 3 1 AAA-like domain ArgK PF03308.11 EIW87071.1 - 0.003 16.3 0.0 0.01 14.6 0.0 1.7 1 1 1 2 2 2 1 ArgK protein Mg_chelatase PF01078.16 EIW87071.1 - 0.0038 16.4 0.0 0.019 14.1 0.0 1.9 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EIW87071.1 - 0.0048 16.6 0.0 0.012 15.2 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 EIW87071.1 - 0.015 15.0 0.1 0.049 13.3 0.1 1.9 1 1 1 2 2 2 0 NTPase AAA_11 PF13086.1 EIW87071.1 - 0.023 14.2 0.0 0.035 13.6 0.0 1.3 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EIW87071.1 - 0.026 14.8 0.1 0.045 14.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain KTI12 PF08433.5 EIW87071.1 - 0.03 13.5 0.0 0.056 12.6 0.0 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 FtsK_SpoIIIE PF01580.13 EIW87071.1 - 0.056 12.8 0.0 0.18 11.2 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family DEAD PF00270.24 EIW87071.1 - 0.059 12.8 0.0 0.62 9.5 0.0 2.3 1 1 0 2 2 2 0 DEAD/DEAH box helicase RNA_helicase PF00910.17 EIW87071.1 - 0.066 13.3 0.1 0.25 11.5 0.0 2.0 1 1 0 1 1 1 0 RNA helicase SRP54 PF00448.17 EIW87071.1 - 0.069 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 EIW87071.1 - 0.15 12.3 0.1 0.46 10.7 0.0 1.7 1 1 0 1 1 1 0 ABC transporter tRNA-synt_2b PF00587.20 EIW87072.1 - 1.7e-26 92.8 0.0 2.9e-26 92.1 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EIW87072.1 - 2e-10 40.6 0.5 3.2e-10 39.9 0.3 1.3 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Pkinase PF00069.20 EIW87073.1 - 3.3e-38 131.3 0.0 3.9e-38 131.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW87073.1 - 1e-13 50.9 0.0 1.4e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW87073.1 - 4.6e-05 23.2 0.0 0.0024 17.6 0.0 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EIW87073.1 - 0.013 14.3 0.1 0.019 13.7 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Chitin_synth_1 PF01644.12 EIW87074.1 - 1.4e-74 249.3 0.2 2e-74 248.7 0.1 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 EIW87074.1 - 3.3e-24 85.1 0.0 3.7e-19 68.5 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 EIW87074.1 - 3e-23 81.3 0.2 9.3e-23 79.7 0.2 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_tranf_2_3 PF13641.1 EIW87074.1 - 2.9e-09 37.0 0.0 9.6e-09 35.3 0.0 1.8 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EIW87074.1 - 8.1e-07 28.9 5.9 8.1e-07 28.9 4.1 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Peptidase_M50 PF02163.17 EIW87074.1 - 0.041 12.8 0.1 0.65 8.9 0.0 2.4 2 1 0 2 2 2 0 Peptidase family M50 Dopey_N PF04118.9 EIW87075.1 - 3e-109 364.5 0.8 5.8e-109 363.5 0.1 1.8 2 0 0 2 2 2 1 Dopey, N-terminal ABC2_membrane PF01061.19 EIW87076.1 - 7.8e-70 234.3 50.5 1.1e-36 125.9 14.1 3.3 5 0 0 5 5 4 2 ABC-2 type transporter ABC_tran PF00005.22 EIW87076.1 - 3.5e-32 111.5 0.0 3.1e-16 59.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EIW87076.1 - 4.6e-22 77.6 8.2 1.4e-18 66.3 0.0 3.3 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EIW87076.1 - 2.8e-09 36.9 0.2 7.6e-09 35.5 0.1 1.9 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal cobW PF02492.14 EIW87076.1 - 2e-07 30.6 0.1 0.0075 15.7 0.0 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EIW87076.1 - 9.1e-07 29.0 0.1 0.097 12.8 0.0 3.3 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EIW87076.1 - 3.6e-06 26.5 0.0 0.028 13.8 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EIW87076.1 - 8.8e-05 22.4 0.0 0.2 11.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EIW87076.1 - 0.00011 22.9 0.0 0.55 11.0 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EIW87076.1 - 0.00049 19.5 0.2 0.041 13.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 EIW87076.1 - 0.00068 19.6 0.1 0.36 10.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EIW87076.1 - 0.0026 17.2 0.1 0.23 10.8 0.0 3.2 2 1 0 3 3 3 1 AAA-like domain SMC_N PF02463.14 EIW87076.1 - 0.006 15.8 0.0 0.16 11.1 0.0 2.9 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 EIW87076.1 - 0.0086 15.5 0.0 3.2 7.1 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_19 PF13245.1 EIW87076.1 - 0.011 15.5 1.0 1.1 9.0 0.0 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 EIW87076.1 - 0.014 15.5 0.0 3.2 7.9 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EIW87076.1 - 0.015 14.8 0.2 4.6 6.9 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 EIW87076.1 - 0.021 14.8 2.5 1.2 9.0 0.3 3.3 3 1 0 3 3 3 0 AAA ATPase domain AAA_30 PF13604.1 EIW87076.1 - 0.025 14.1 0.1 2.9 7.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EIW87076.1 - 0.034 13.3 0.0 0.096 11.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_21 PF13304.1 EIW87076.1 - 0.084 12.8 0.0 21 4.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EIW87076.1 - 0.09 12.7 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EIW87076.1 - 0.11 12.8 5.2 1.3 9.3 0.0 3.0 3 0 0 3 3 2 0 AAA domain Prefoldin_2 PF01920.15 EIW87077.1 - 9.2e-15 54.3 7.1 1.1e-14 54.0 4.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit Tropomyosin_1 PF12718.2 EIW87077.1 - 0.15 11.8 8.1 0.068 13.0 2.9 2.0 2 0 0 2 2 2 0 Tropomyosin like DUF4145 PF13643.1 EIW87077.1 - 0.47 10.3 2.2 2.2 8.2 1.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4145) DUF3552 PF12072.3 EIW87077.1 - 0.57 9.3 7.5 0.5 9.5 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) TBPIP PF07106.8 EIW87077.1 - 0.63 9.5 6.7 0.11 12.0 1.6 1.8 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prefoldin PF02996.12 EIW87077.1 - 1.2 8.7 5.6 0.64 9.6 1.0 2.2 1 1 1 2 2 2 0 Prefoldin subunit DivIC PF04977.10 EIW87077.1 - 1.6 8.2 6.8 0.19 11.2 0.6 2.1 2 0 0 2 2 2 0 Septum formation initiator CorA PF01544.13 EIW87077.1 - 2.9 6.8 6.1 8.4 5.3 1.4 2.0 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Coat_F PF07875.7 EIW87077.1 - 2.9 8.0 8.3 11 6.2 0.2 3.2 4 0 0 4 4 4 0 Coat F domain OmpH PF03938.9 EIW87077.1 - 5 7.0 11.3 8.8 6.2 7.8 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) XhlA PF10779.4 EIW87077.1 - 10 6.1 11.8 0.6 10.0 2.3 2.1 2 0 0 2 2 2 0 Haemolysin XhlA GTP_EFTU PF00009.22 EIW87078.1 - 1.1e-42 145.6 0.1 1.7e-42 144.9 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EIW87078.1 - 4.7e-26 90.6 0.0 9.5e-26 89.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EIW87078.1 - 4.2e-21 74.6 0.0 9.5e-21 73.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EIW87078.1 - 5.9e-09 35.9 0.0 1.5e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EIW87078.1 - 3.8e-06 26.8 0.2 7.6e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 EIW87078.1 - 5.4e-05 22.9 0.0 0.00013 21.7 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Miro PF08477.8 EIW87078.1 - 0.00011 22.6 0.4 0.00022 21.7 0.3 1.5 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EIW87078.1 - 0.008 15.4 0.1 0.018 14.2 0.1 1.6 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EIW87078.1 - 0.045 13.1 0.2 0.16 11.3 0.1 1.8 1 1 0 1 1 1 0 Ras family Dynamin_N PF00350.18 EIW87078.1 - 0.051 13.3 0.4 8.4 6.1 0.3 2.5 1 1 0 2 2 2 0 Dynamin family Calreticulin PF00262.13 EIW87079.1 - 5.3e-147 489.2 6.3 6.3e-147 489.0 4.3 1.1 1 0 0 1 1 1 1 Calreticulin family F-box-like PF12937.2 EIW87080.1 - 2.3e-10 40.0 2.8 8.7e-10 38.1 1.9 2.1 1 0 0 1 1 1 1 F-box-like polyprenyl_synt PF00348.12 EIW87082.1 - 3.1e-44 150.8 0.0 7.4e-41 139.7 0.0 2.2 2 0 0 2 2 2 2 Polyprenyl synthetase Glyco_hydro_12 PF01670.11 EIW87083.1 - 1.1e-35 122.7 4.1 1.1e-35 122.7 2.8 2.0 1 1 1 2 2 2 1 Glycosyl hydrolase family 12 F-box-like PF12937.2 EIW87084.1 - 4.1e-09 36.0 3.4 1.5e-08 34.2 1.8 2.3 2 0 0 2 2 2 1 F-box-like PRANC PF09372.5 EIW87084.1 - 0.0052 16.7 0.1 0.0095 15.8 0.1 1.3 1 0 0 1 1 1 1 PRANC domain F-box PF00646.28 EIW87084.1 - 0.0075 15.9 0.6 0.028 14.0 0.4 2.0 1 0 0 1 1 1 1 F-box domain MatE PF01554.13 EIW87086.1 - 1.8e-16 60.1 15.7 1.8e-11 43.9 1.6 2.8 3 0 0 3 3 3 2 MatE Methyltransf_11 PF08241.7 EIW87087.1 - 5.5e-27 94.1 0.0 9.5e-27 93.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW87087.1 - 2.1e-26 92.3 0.0 2.2e-26 92.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW87087.1 - 3.5e-18 66.2 0.0 5.8e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW87087.1 - 1.2e-17 64.0 0.0 2.1e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW87087.1 - 1.4e-17 63.9 0.0 2.2e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW87087.1 - 1.6e-17 63.4 0.0 2.1e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EIW87087.1 - 8.7e-17 61.3 0.0 1.4e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW87087.1 - 1.5e-10 40.6 0.0 2.7e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EIW87087.1 - 1.9e-10 40.7 0.5 4.5e-10 39.5 0.3 1.5 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EIW87087.1 - 2e-09 37.3 0.0 2.6e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EIW87087.1 - 2.3e-08 33.6 0.0 3.2e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_4 PF02390.12 EIW87087.1 - 1.1e-06 27.8 0.0 2.2e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_29 PF03141.11 EIW87087.1 - 1.7e-06 26.6 3.2 2.3e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 EIW87087.1 - 7.4e-06 25.1 0.0 1.1e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NodS PF05401.6 EIW87087.1 - 5.1e-05 22.7 0.0 7.4e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.1 EIW87087.1 - 0.0015 18.2 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EIW87087.1 - 0.002 18.1 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase UPF0020 PF01170.13 EIW87087.1 - 0.002 17.7 0.0 0.0035 16.9 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_9 PF08003.6 EIW87087.1 - 0.0022 16.7 0.0 0.0039 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_2 PF00891.13 EIW87087.1 - 0.0022 17.2 0.1 0.0032 16.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase DREV PF05219.7 EIW87087.1 - 0.0032 16.4 0.0 0.0049 15.7 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase CMAS PF02353.15 EIW87087.1 - 0.007 15.4 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EIW87087.1 - 0.0072 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CheR PF01739.13 EIW87087.1 - 0.017 14.4 0.0 0.049 12.9 0.0 1.7 1 1 1 2 2 2 0 CheR methyltransferase, SAM binding domain DUF938 PF06080.7 EIW87087.1 - 0.032 13.7 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FmrO PF07091.6 EIW87087.1 - 0.046 12.7 0.0 0.069 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_8 PF05148.10 EIW87087.1 - 0.075 12.6 0.0 0.37 10.3 0.0 1.9 1 1 0 1 1 1 0 Hypothetical methyltransferase RRM_1 PF00076.17 EIW87088.1 - 7.1e-15 54.4 0.0 1.1e-11 44.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW87088.1 - 6.4e-09 35.5 0.0 0.0019 17.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW87088.1 - 1e-06 28.5 0.0 7.7e-06 25.7 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.17 EIW87089.1 - 1.7e-53 180.3 0.8 4.1e-52 175.8 0.5 2.0 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EIW87089.1 - 4e-16 59.5 0.0 1.1e-15 58.1 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EIW87089.1 - 2.1e-08 33.6 0.3 1e-06 28.0 0.2 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EIW87089.1 - 3e-06 26.7 0.0 4e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EIW87089.1 - 0.0026 17.6 0.0 0.0054 16.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EIW87089.1 - 0.046 12.8 0.0 0.12 11.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIW87089.1 - 0.054 13.6 0.0 0.47 10.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EIW87089.1 - 0.06 13.3 0.2 0.17 11.8 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain DUF89 PF01937.14 EIW87089.1 - 0.091 11.5 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF89 RasGEF PF00617.14 EIW87090.1 - 2.4e-38 131.7 0.5 3.5e-38 131.2 0.4 1.2 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EIW87090.1 - 7.6e-21 74.1 0.0 1.6e-20 73.1 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 EIW87090.1 - 2.4e-12 46.0 0.7 5.2e-12 44.9 0.1 1.9 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EIW87090.1 - 1.2e-09 37.6 0.4 4.2e-09 35.8 0.0 2.2 3 0 0 3 3 3 1 Variant SH3 domain SH3_2 PF07653.12 EIW87090.1 - 1.4e-09 37.2 0.0 2.6e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain Ist1 PF03398.9 EIW87091.1 - 6.9e-59 197.9 3.5 8.4e-59 197.6 2.4 1.1 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Methyltransf_23 PF13489.1 EIW87092.1 - 5.8e-09 35.8 0.0 8.5e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW87092.1 - 3.3e-08 33.8 0.1 1e-07 32.3 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW87092.1 - 1.7e-07 31.7 0.1 1.2e-06 29.0 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW87092.1 - 2.1e-05 24.8 0.0 8.4e-05 22.9 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW87092.1 - 3.5e-05 23.4 0.0 0.0011 18.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EIW87092.1 - 0.00023 20.2 0.0 0.0005 19.1 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.1 EIW87092.1 - 0.00057 20.2 0.2 0.0037 17.6 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EIW87092.1 - 0.0012 18.8 0.0 0.0019 18.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 EIW87092.1 - 0.0022 17.2 0.1 0.0038 16.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Ubie_methyltran PF01209.13 EIW87092.1 - 0.0078 15.3 0.0 0.094 11.8 0.0 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EIW87092.1 - 0.046 13.0 0.1 0.098 12.0 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 EIW87092.1 - 0.056 13.4 0.0 1.2 9.2 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain BRK PF07533.11 EIW87092.1 - 0.11 11.9 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 BRK domain DSHCT PF08148.7 EIW87093.1 - 1e-61 207.3 0.4 2.2e-61 206.2 0.3 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EIW87093.1 - 5.8e-19 68.2 0.0 1.3e-18 67.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase rRNA_proc-arch PF13234.1 EIW87093.1 - 7.8e-08 31.8 0.0 1.7e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 rRNA-processing arch domain Helicase_C PF00271.26 EIW87093.1 - 7.3e-05 22.5 0.0 0.00018 21.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HTH_17 PF12728.2 EIW87094.1 - 0.057 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain PAT1 PF09770.4 EIW87095.1 - 8.9 4.4 26.8 13 3.8 18.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2414 PF10309.4 EIW87096.1 - 0.00085 18.9 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) RNA_bind PF08675.6 EIW87096.1 - 0.0053 16.7 0.0 0.0087 16.0 0.0 1.3 1 0 0 1 1 1 1 RNA binding domain RRM_3 PF08777.6 EIW87096.1 - 0.0096 15.7 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif DUF837 PF05769.6 EIW87097.1 - 1.8e-09 37.4 6.6 1.8e-06 27.6 1.9 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF837) Herpes_BLRF2 PF05812.7 EIW87097.1 - 0.042 13.6 4.6 0.13 12.0 0.0 3.0 3 0 0 3 3 3 0 Herpesvirus BLRF2 protein DNA_photolyase PF00875.13 EIW87097.1 - 0.046 13.4 1.7 0.082 12.6 0.4 1.8 1 1 1 2 2 2 0 DNA photolyase bZIP_2 PF07716.10 EIW87097.1 - 0.66 9.8 7.3 0.63 9.9 1.1 2.9 2 0 0 2 2 2 0 Basic region leucine zipper DUF2404 PF10296.4 EIW87101.1 - 2.4e-25 88.4 0.0 4.8e-25 87.4 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) PH_9 PF15410.1 EIW87101.1 - 0.18 11.9 0.0 0.42 10.7 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain TFIIF_alpha PF05793.7 EIW87102.1 - 0.0025 16.2 1.7 0.0025 16.2 1.2 2.4 3 0 0 3 3 3 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Myosin_tail_1 PF01576.14 EIW87103.1 - 4.2e-08 31.4 113.6 1.3e-05 23.1 24.8 4.4 2 1 2 4 4 4 3 Myosin tail Tropomyosin PF00261.15 EIW87103.1 - 3.4e-06 26.3 30.6 3.4e-06 26.3 21.2 4.9 2 1 3 5 5 5 2 Tropomyosin EzrA PF06160.7 EIW87103.1 - 0.0016 16.7 16.8 0.0016 16.7 11.7 6.0 2 1 4 6 6 6 2 Septation ring formation regulator, EzrA CENP-F_leu_zip PF10473.4 EIW87103.1 - 0.0024 17.7 24.4 0.0024 17.7 16.9 6.9 2 1 2 6 6 6 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF948 PF06103.6 EIW87103.1 - 0.0047 16.7 1.3 0.0047 16.7 0.9 6.8 3 1 4 8 8 8 2 Bacterial protein of unknown function (DUF948) Tropomyosin_1 PF12718.2 EIW87103.1 - 0.0056 16.5 22.2 0.0056 16.5 15.4 7.1 2 1 5 7 7 7 3 Tropomyosin like SlyX PF04102.7 EIW87103.1 - 0.028 14.7 0.2 0.028 14.7 0.1 10.0 4 2 7 12 12 11 0 SlyX AAA_13 PF13166.1 EIW87103.1 - 0.44 8.9 78.6 1.9 6.8 6.4 3.9 1 1 3 4 4 4 0 AAA domain LIF_OSM PF01291.12 EIW87103.1 - 0.96 9.3 10.3 0.22 11.4 0.5 3.3 3 0 0 3 3 3 0 LIF / OSM family Spc7 PF08317.6 EIW87103.1 - 1.3 7.5 90.2 1.3 7.6 4.0 5.7 2 1 4 6 6 6 0 Spc7 kinetochore protein Reo_sigmaC PF04582.7 EIW87103.1 - 3.8 6.5 48.0 0.072 12.2 5.2 5.4 2 1 2 5 5 5 0 Reovirus sigma C capsid protein WD40 PF00400.27 EIW87104.1 - 1.4e-53 176.9 20.8 8e-09 35.0 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EIW87104.1 - 0.00065 19.4 0.0 0.22 11.2 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Sfi1 PF08457.5 EIW87104.1 - 0.12 10.7 0.5 0.16 10.2 0.3 1.1 1 0 0 1 1 1 0 Sfi1 spindle body protein Cytochrom_D1 PF02239.11 EIW87104.1 - 0.13 10.5 0.0 0.22 9.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome D1 heme domain MARVEL PF01284.18 EIW87105.1 - 2.1e-06 27.6 21.0 2.4e-06 27.4 13.7 1.7 1 1 0 1 1 1 1 Membrane-associating domain DUF2668 PF10873.3 EIW87105.1 - 0.077 13.1 0.2 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) Gate PF07670.9 EIW87105.1 - 0.13 12.1 3.9 0.29 11.0 2.7 1.7 1 1 0 1 1 1 0 Nucleoside recognition DUF2871 PF11070.3 EIW87105.1 - 3.4 7.8 10.4 6.4 6.9 5.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2871) dsrm PF00035.20 EIW87106.1 - 0.00012 22.5 0.0 0.00015 22.3 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif dsrm PF00035.20 EIW87107.1 - 9.2e-11 42.1 0.0 1.1e-10 41.8 0.0 1.1 1 0 0 1 1 1 1 Double-stranded RNA binding motif dsrm PF00035.20 EIW87108.1 - 2.4e-09 37.6 0.0 3.7e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif UCH PF00443.24 EIW87109.1 - 1.9e-31 109.1 0.0 2.6e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EIW87109.1 - 2.5e-10 40.2 0.2 4.4e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein Rsm22 PF09243.5 EIW87110.1 - 1.7e-40 138.7 0.0 3.6e-27 95.1 0.0 3.5 2 1 0 2 2 2 2 Mitochondrial small ribosomal subunit Rsm22 Ribosomal_L1 PF00687.16 EIW87111.1 - 4.1e-14 52.4 0.0 5.6e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family MRP-L28 PF09812.4 EIW87112.1 - 9.9e-12 44.9 1.5 1.7e-08 34.4 0.8 2.2 2 0 0 2 2 2 2 Mitochondrial ribosomal protein L28 PCI PF01399.22 EIW87113.1 - 2.5e-18 66.3 0.4 7.1e-18 64.8 0.2 1.9 1 1 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 EIW87113.1 - 9.1e-10 38.4 2.1 9.3e-10 38.4 0.2 1.8 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EIW87113.1 - 0.047 13.2 4.3 1.1 8.7 3.0 2.2 1 1 0 1 1 1 0 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PIP5K PF01504.13 EIW87114.1 - 6.1e-63 212.2 0.1 1.1e-62 211.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EIW87114.1 - 1.6e-21 76.5 0.0 2.6e-21 75.8 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EIW87114.1 - 8.2e-19 67.2 10.6 1.4e-18 66.5 6.4 2.0 2 0 0 2 2 2 1 FYVE zinc finger IBR PF01485.16 EIW87114.1 - 2 8.3 9.2 0.44 10.4 3.3 2.1 2 0 0 2 2 2 0 IBR domain Bromodomain PF00439.20 EIW87115.1 - 8.1e-57 189.1 0.1 3.2e-21 75.0 0.2 3.6 3 0 0 3 3 3 3 Bromodomain Peptidase_M1 PF01433.15 EIW87115.1 - 1.7e-14 53.7 0.0 1.2e-08 34.4 0.0 3.2 2 1 0 3 3 3 3 Peptidase family M1 Peptidase_MA_2 PF13485.1 EIW87115.1 - 0.001 19.0 0.0 0.0077 16.2 0.0 2.4 3 0 0 3 3 3 1 Peptidase MA superfamily TBCA PF02970.11 EIW87116.1 - 1.5e-22 79.4 9.2 2e-22 79.0 6.4 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A PT-HINT PF07591.6 EIW87116.1 - 0.06 13.2 0.2 0.081 12.8 0.1 1.2 1 0 0 1 1 1 0 Pretoxin HINT domain FANCAA PF15146.1 EIW87116.1 - 0.13 11.1 0.4 0.15 10.9 0.3 1.1 1 0 0 1 1 1 0 Fanconi anemia-associated HisKA PF00512.20 EIW87116.1 - 0.17 11.8 2.2 0.42 10.6 1.6 1.7 1 1 0 1 1 1 0 His Kinase A (phospho-acceptor) domain DUF2361 PF10153.4 EIW87116.1 - 1.1 9.4 6.5 1.3 9.2 4.5 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) HLH PF00010.21 EIW87117.1 - 6.6e-08 32.1 2.5 6.6e-08 32.1 1.7 2.2 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain WD40_alt PF14077.1 EIW87117.1 - 0.13 11.9 0.1 0.25 10.9 0.1 1.4 1 0 0 1 1 1 0 Alternative WD40 repeat motif Orbi_VP5 PF00901.12 EIW87117.1 - 1.3 7.1 6.4 1.7 6.7 4.5 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 IncA PF04156.9 EIW87117.1 - 2.9 7.4 7.7 3.8 7.0 5.3 1.1 1 0 0 1 1 1 0 IncA protein HLH PF00010.21 EIW87120.1 - 8.4e-08 31.7 1.1 8.4e-08 31.7 0.8 2.6 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain IncA PF04156.9 EIW87120.1 - 0.00071 19.2 4.2 0.00099 18.7 2.9 1.2 1 0 0 1 1 1 1 IncA protein FlaC_arch PF05377.6 EIW87120.1 - 0.0018 18.1 0.4 0.0047 16.7 0.3 1.6 1 0 0 1 1 1 1 Flagella accessory protein C (FlaC) CENP-F_leu_zip PF10473.4 EIW87120.1 - 0.013 15.3 6.4 0.018 14.8 4.4 1.2 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.4 EIW87120.1 - 0.069 13.2 0.8 0.094 12.8 0.0 1.6 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 EIW87120.1 - 0.31 10.5 4.3 0.46 10.0 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator CAF-1_p150 PF11600.3 EIW87120.1 - 0.37 10.1 8.4 0.6 9.4 5.8 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal APG6 PF04111.7 EIW87120.1 - 1.2 8.0 5.4 2.1 7.3 3.7 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 BTB PF00651.26 EIW87122.1 - 9e-08 32.0 0.0 1.4e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 BTB/POZ domain Aldo_ket_red PF00248.16 EIW87123.1 - 9.2e-63 211.7 0.2 1e-62 211.5 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ICL PF00463.16 EIW87124.1 - 2.6e-186 619.9 0.0 2.9e-186 619.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EIW87124.1 - 8.7e-09 34.9 0.0 1.5e-08 34.1 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Methyltransf_16 PF10294.4 EIW87126.1 - 1.6e-17 63.5 0.0 2.5e-17 62.8 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EIW87126.1 - 0.0014 19.1 0.0 0.0024 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW87126.1 - 0.0066 15.8 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EIW87126.1 - 0.017 14.7 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EIW87126.1 - 0.072 12.6 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Bot1p PF12298.3 EIW87127.1 - 5.9e-25 88.1 0.7 5.9e-25 88.1 0.5 2.0 2 1 0 2 2 2 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.2 EIW87127.1 - 0.025 14.5 0.0 0.025 14.5 0.0 2.2 3 0 0 3 3 3 0 Mitochondrial ribosomal protein subunit L20 MFS_1 PF07690.11 EIW87128.1 - 6.8e-21 74.3 20.5 1.2e-20 73.5 14.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Cpn60_TCP1 PF00118.19 EIW87129.1 - 1e-140 469.6 0.1 1.1e-140 469.4 0.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SNF2_N PF00176.18 EIW87130.1 - 1.9e-59 200.9 0.0 2.7e-59 200.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EIW87130.1 - 2.4e-12 46.5 0.0 4.7e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HIRAN PF08797.6 EIW87130.1 - 3e-11 43.2 0.0 8.7e-11 41.7 0.0 1.8 1 0 0 1 1 1 1 HIRAN domain zf-C3HC4_2 PF13923.1 EIW87130.1 - 5.7e-08 32.6 13.1 1.3e-07 31.5 9.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EIW87130.1 - 7.2e-07 28.7 13.5 1.3e-06 27.9 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EIW87130.1 - 1.4e-06 28.0 10.3 1.4e-06 28.0 7.1 1.8 2 0 0 2 2 2 1 Ring finger domain ResIII PF04851.10 EIW87130.1 - 5e-06 26.4 0.0 1.2e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit zf-C3HC4_4 PF15227.1 EIW87130.1 - 1.6e-05 24.6 13.2 2.9e-05 23.8 9.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.1 EIW87130.1 - 0.00023 20.7 8.6 0.00038 20.0 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EIW87130.1 - 0.00077 19.1 10.0 0.0013 18.3 6.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-MIZ PF02891.15 EIW87130.1 - 0.019 14.4 8.1 0.035 13.6 5.6 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EIW87130.1 - 0.058 12.9 7.1 0.13 11.7 5.0 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 EIW87130.1 - 0.06 13.1 1.5 0.15 11.9 1.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Patched PF02460.13 EIW87130.1 - 0.18 9.6 0.0 0.27 9.1 0.0 1.1 1 0 0 1 1 1 0 Patched family WLM PF08325.5 EIW87131.1 - 3.4e-49 167.2 0.0 5.3e-49 166.6 0.0 1.3 1 0 0 1 1 1 1 WLM domain zf-RanBP PF00641.13 EIW87131.1 - 4.3e-07 28.9 1.5 4.3e-07 28.9 1.1 2.9 2 1 0 2 2 2 1 Zn-finger in Ran binding protein and others DUF45 PF01863.12 EIW87131.1 - 0.00026 20.8 0.1 0.00043 20.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function DUF45 DZR PF12773.2 EIW87131.1 - 0.009 15.8 11.1 0.019 14.7 7.7 1.5 1 0 0 1 1 1 1 Double zinc ribbon DUF2147 PF09917.4 EIW87131.1 - 0.071 13.3 0.0 0.29 11.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2147) SprT-like PF10263.4 EIW87131.1 - 2.4 7.7 6.7 0.58 9.7 0.1 2.4 2 1 0 2 2 2 0 SprT-like family zf-Sec23_Sec24 PF04810.10 EIW87131.1 - 3.5 7.2 11.1 8.8 5.9 0.6 3.3 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger Methyltransf_11 PF08241.7 EIW87132.1 - 2.9e-15 56.5 0.0 5.8e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EIW87132.1 - 1.6e-11 44.4 0.0 3.4e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EIW87132.1 - 4.7e-11 42.6 0.0 1e-10 41.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EIW87132.1 - 5.8e-10 39.7 0.0 1.1e-09 38.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EIW87132.1 - 1.7e-08 33.8 0.0 2.7e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EIW87132.1 - 2e-08 34.5 0.0 4.9e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW87132.1 - 3.4e-08 33.2 0.0 6e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EIW87132.1 - 1.9e-06 27.8 0.0 4.3e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW87132.1 - 9.6e-05 21.8 0.0 0.00017 21.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 EIW87132.1 - 0.00036 20.5 0.0 0.00063 19.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 EIW87132.1 - 0.00045 19.4 0.0 0.00087 18.5 0.0 1.5 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_4 PF02390.12 EIW87132.1 - 0.0096 14.9 0.0 0.079 12.0 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.15 EIW87132.1 - 0.034 13.2 0.0 0.067 12.2 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.11 EIW87132.1 - 0.12 10.7 0.0 0.24 9.7 0.0 1.4 1 1 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.8 EIW87132.1 - 0.29 10.1 0.0 0.45 9.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MFS_1 PF07690.11 EIW87133.1 - 1.1e-12 47.4 61.1 1.8e-10 40.0 27.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily SF3b10 PF07189.6 EIW87136.1 - 2.6e-33 113.6 0.0 3.2e-33 113.3 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) CobT PF06213.7 EIW87137.1 - 0.025 13.7 7.5 0.028 13.5 5.2 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4094 PF13334.1 EIW87137.1 - 0.034 14.5 0.0 0.061 13.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DUF2457 PF10446.4 EIW87137.1 - 0.27 9.9 7.4 0.3 9.7 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Daxx PF03344.10 EIW87137.1 - 0.36 9.2 8.1 0.41 9.0 5.6 1.0 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EIW87137.1 - 0.44 8.5 6.8 0.57 8.1 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 EIW87137.1 - 2.2 7.5 11.2 2.5 7.3 7.7 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EIW87137.1 - 2.2 6.1 10.8 2.3 6.0 7.5 1.0 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.6 EIW87137.1 - 4.3 5.0 7.3 5 4.8 5.1 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen LRR_6 PF13516.1 EIW87138.1 - 6.3e-07 28.8 12.6 0.45 10.7 0.2 6.9 7 0 0 7 7 7 3 Leucine Rich repeat LRR_4 PF12799.2 EIW87138.1 - 7.4e-06 25.4 5.0 4.7 6.9 0.0 5.7 4 1 0 5 5 5 1 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EIW87138.1 - 3.5e-05 23.4 0.1 0.00015 21.4 0.0 2.1 1 1 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EIW87138.1 - 0.00071 19.2 10.2 1.3 8.8 0.4 5.1 4 1 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 EIW87138.1 - 0.0091 15.8 13.0 8.5 6.8 0.1 6.5 6 0 0 6 6 6 2 Leucine Rich Repeat F-box PF00646.28 EIW87138.1 - 0.01 15.4 1.3 0.082 12.5 0.0 2.7 2 0 0 2 2 2 0 F-box domain LRR_7 PF13504.1 EIW87138.1 - 0.066 13.4 6.1 18 6.1 0.1 5.8 5 0 0 5 5 5 0 Leucine rich repeat YABBY PF04690.8 EIW87139.1 - 1e-08 35.6 0.1 1.1e-08 35.5 0.1 1.1 1 0 0 1 1 1 1 YABBY protein HMG_box PF00505.14 EIW87139.1 - 0.0016 18.6 1.0 0.0024 18.1 0.7 1.3 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EIW87139.1 - 0.0021 18.3 0.3 0.0034 17.7 0.2 1.3 1 0 0 1 1 1 1 HMG-box domain DUF1014 PF06244.7 EIW87139.1 - 0.0037 17.4 0.4 0.004 17.3 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1014) Sec1 PF00995.18 EIW87140.1 - 1.5e-118 396.9 0.0 1.9e-118 396.5 0.0 1.1 1 0 0 1 1 1 1 Sec1 family cNMP_binding PF00027.24 EIW87141.1 - 3.5e-41 138.9 0.1 9.1e-18 63.8 0.0 4.5 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Patatin PF01734.17 EIW87141.1 - 2.9e-17 63.2 3.1 1e-15 58.2 2.2 2.6 1 1 0 1 1 1 1 Patatin-like phospholipase Homeobox PF00046.24 EIW87142.1 - 1.3e-40 136.8 14.3 9e-18 63.6 0.4 3.7 3 0 0 3 3 3 3 Homeobox domain Homeobox_KN PF05920.6 EIW87142.1 - 2.9e-16 58.8 4.3 3.4e-08 33.0 0.1 4.0 4 0 0 4 4 4 3 Homeobox KN domain HTH_3 PF01381.17 EIW87142.1 - 0.00042 20.0 0.4 2.1 8.2 0.0 3.3 3 0 0 3 3 3 2 Helix-turn-helix Homez PF11569.3 EIW87142.1 - 0.0054 15.7 0.3 1.1 8.3 0.0 2.6 2 0 0 2 2 2 2 Homeodomain leucine-zipper encoding, Homez HTH_26 PF13443.1 EIW87142.1 - 0.03 14.5 0.3 5.5 7.2 0.0 2.7 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain HTH_32 PF13565.1 EIW87142.1 - 1.3 9.9 8.0 5 8.0 0.5 3.7 3 0 0 3 3 3 0 Homeodomain-like domain Fumble PF03630.9 EIW87143.1 - 6.1e-110 367.2 0.0 4.1e-88 295.5 0.0 2.9 2 1 0 2 2 2 2 Fumble Adaptin_N PF01602.15 EIW87144.1 - 3.5e-115 385.3 0.0 4.6e-115 384.9 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EIW87144.1 - 5.5e-58 195.0 5.5 1.3e-57 193.8 3.8 1.7 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EIW87144.1 - 4.7e-13 49.2 2.8 0.0012 19.0 0.1 6.3 2 2 4 6 6 6 3 HEAT repeats HEAT PF02985.17 EIW87144.1 - 0.00097 19.0 6.0 5.6 7.3 0.0 6.1 5 0 0 5 5 5 1 HEAT repeat Arm PF00514.18 EIW87144.1 - 0.011 15.5 0.1 27 4.7 0.0 4.4 3 1 1 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 EIW87144.1 - 0.085 13.3 0.6 17 6.2 0.1 4.6 6 0 0 6 6 6 0 PBS lyase HEAT-like repeat Transformer PF06495.6 EIW87145.1 - 0.04 13.7 3.4 0.1 12.4 2.3 1.7 1 0 0 1 1 1 0 Fruit fly transformer protein DUF4604 PF15377.1 EIW87145.1 - 3.4 7.8 19.0 0.27 11.4 9.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) GFA PF04828.9 EIW87146.1 - 3.1e-11 43.0 3.2 4.6e-11 42.4 2.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Fer4_8 PF13183.1 EIW87146.1 - 0.09 12.8 5.8 0.19 11.8 4.1 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain Barwin PF00967.12 EIW87146.1 - 0.42 10.3 3.7 0.29 10.8 0.4 2.0 1 1 1 2 2 2 0 Barwin family Sgf11 PF08209.6 EIW87146.1 - 0.57 9.5 7.2 0.32 10.3 0.8 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Fer4_10 PF13237.1 EIW87146.1 - 0.57 10.0 6.8 1.6 8.5 4.7 1.8 1 1 0 1 1 1 0 4Fe-4S dicluster domain MFS_1 PF07690.11 EIW87147.1 - 7.8e-21 74.1 24.1 1.1e-20 73.6 16.7 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Peptidase_M50 PF02163.17 EIW87147.1 - 0.22 10.4 2.1 2.6 6.9 0.1 2.7 2 1 0 2 2 2 0 Peptidase family M50 WD40 PF00400.27 EIW87148.1 - 3.8e-35 118.4 9.8 3.8e-09 36.0 0.1 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EIW87148.1 - 4.5e-30 103.3 0.2 1.4e-29 101.8 0.1 1.9 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex DUF3312 PF11768.3 EIW87148.1 - 0.00045 18.5 0.0 0.00063 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3312) RAMP4 PF06624.7 EIW87149.1 - 1.5e-08 34.0 0.1 1.9e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Ribosome associated membrane protein RAMP4 ROKNT PF08067.6 EIW87149.1 - 0.047 13.5 0.8 0.061 13.1 0.5 1.1 1 0 0 1 1 1 0 ROKNT (NUC014) domain DUF3040 PF11239.3 EIW87149.1 - 0.1 12.6 0.1 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) DUF2431 PF10354.4 EIW87150.1 - 1.7e-37 128.9 0.0 4.8e-37 127.4 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) Fip1 PF05182.8 EIW87151.1 - 2.2e-20 71.6 0.7 3.5e-20 71.0 0.5 1.3 1 0 0 1 1 1 1 Fip1 motif ING PF12998.2 EIW87153.1 - 1.5e-12 47.7 0.1 2.6e-12 46.9 0.1 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EIW87153.1 - 1.7e-07 30.8 5.4 2.8e-07 30.1 3.8 1.4 1 0 0 1 1 1 1 PHD-finger RCR PF12273.3 EIW87153.1 - 3.1 8.3 6.4 7.3 7.1 4.4 1.6 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red zf-RING_2 PF13639.1 EIW87156.1 - 0.00027 20.7 0.1 0.00058 19.6 0.1 1.6 1 0 0 1 1 1 1 Ring finger domain RRN7 PF11781.3 EIW87156.1 - 0.026 14.0 0.3 0.067 12.6 0.2 1.7 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-RING_5 PF14634.1 EIW87156.1 - 0.04 13.6 1.0 0.053 13.2 0.1 1.6 2 0 0 2 2 2 0 zinc-RING finger domain Pellino PF04710.9 EIW87156.1 - 0.12 11.0 0.1 0.15 10.6 0.1 1.1 1 0 0 1 1 1 0 Pellino zf-rbx1 PF12678.2 EIW87156.1 - 0.16 12.0 1.0 0.39 10.8 0.7 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger zf-Mss51 PF13824.1 EIW87156.1 - 1.1 9.1 4.1 0.21 11.4 0.3 1.7 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 YqzH PF14164.1 EIW87157.1 - 0.13 12.1 0.2 0.4 10.6 0.1 1.8 1 0 0 1 1 1 0 YqzH-like protein SseC PF04888.7 EIW87159.1 - 0.49 9.6 4.7 0.68 9.2 3.2 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Sporozoite_P67 PF05642.6 EIW87159.1 - 1.7 6.4 11.8 2 6.1 8.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cation_efflux PF01545.16 EIW87160.1 - 6.1e-32 110.8 6.5 7.1e-32 110.6 4.5 1.0 1 0 0 1 1 1 1 Cation efflux family DUF4395 PF14340.1 EIW87160.1 - 0.016 15.2 0.7 2.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) Pkinase PF00069.20 EIW87161.1 - 1.4e-71 240.6 0.0 2e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW87161.1 - 5.3e-52 176.4 0.0 7.4e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW87161.1 - 4.6e-05 22.5 0.0 0.00088 18.3 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF1241 PF06840.6 EIW87161.1 - 0.0044 16.2 0.5 0.0078 15.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1241) Adaptin_N PF01602.15 EIW87162.1 - 1.3e-107 360.2 0.2 1.7e-107 359.9 0.1 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EIW87162.1 - 1.9e-10 40.8 8.5 0.0032 17.7 0.0 6.0 4 3 3 7 7 7 4 HEAT repeats Cnd1 PF12717.2 EIW87162.1 - 1.2e-06 28.4 0.9 0.081 12.7 0.3 3.2 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EIW87162.1 - 8.3e-05 22.3 8.1 2.7 8.3 0.0 7.0 7 0 0 7 7 6 1 HEAT repeat DUF2435 PF10363.4 EIW87162.1 - 0.00021 21.1 1.2 0.88 9.5 0.0 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF2435) Nipped-B_C PF12830.2 EIW87162.1 - 0.00082 19.0 0.7 1.2 8.7 0.0 3.7 3 1 0 3 3 3 2 Sister chromatid cohesion C-terminus HEAT_EZ PF13513.1 EIW87162.1 - 0.003 18.0 8.1 6 7.4 0.0 6.7 7 1 1 8 8 8 1 HEAT-like repeat Arm PF00514.18 EIW87162.1 - 0.0057 16.4 2.3 19 5.2 0.0 4.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Proteasom_PSMB PF10508.4 EIW87162.1 - 0.028 12.6 1.0 1.5 6.9 0.2 2.6 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit ParcG PF10274.4 EIW87162.1 - 0.058 13.2 0.4 13 5.5 0.0 3.0 3 0 0 3 3 3 0 Parkin co-regulated protein RasGEF_N_2 PF14663.1 EIW87162.1 - 0.07 13.0 0.9 4 7.4 0.0 3.4 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RabGAP-TBC PF00566.13 EIW87163.1 - 9.8e-46 155.9 0.0 1.3e-45 155.5 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain F-box-like PF12937.2 EIW87164.1 - 2.2e-06 27.2 0.0 8.5e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EIW87164.1 - 0.0084 15.7 6.3 7.9 6.2 0.0 5.6 5 2 1 6 6 6 2 Leucine Rich repeats (2 copies) Nramp PF01566.13 EIW87165.1 - 1.9e-85 286.8 31.3 4e-48 164.0 5.6 2.5 3 0 0 3 3 3 2 Natural resistance-associated macrophage protein RNase_H PF00075.19 EIW87166.1 - 3.7e-28 98.5 0.0 5.4e-28 97.9 0.0 1.2 1 0 0 1 1 1 1 RNase H Cauli_VI PF01693.11 EIW87166.1 - 0.098 12.6 0.1 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Caulimovirus viroplasmin FAA_hydrolase PF01557.13 EIW87167.1 - 4e-44 150.6 0.0 7.8e-44 149.7 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family zf-C2H2 PF00096.21 EIW87168.1 - 2e-15 56.0 51.0 0.01 16.1 0.4 8.4 8 0 0 8 8 8 7 Zinc finger, C2H2 type zf-met PF12874.2 EIW87168.1 - 3.2e-15 55.7 32.9 0.0025 17.9 1.5 7.5 8 0 0 8 8 8 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIW87168.1 - 3.8e-14 52.3 40.7 0.00063 19.7 3.6 7.9 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EIW87168.1 - 4.6e-10 39.1 38.2 0.08 13.3 0.7 8.0 7 1 1 8 8 8 6 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EIW87168.1 - 2.3e-05 24.4 33.7 0.015 15.3 0.9 5.2 1 1 2 4 4 4 3 C2H2 type zinc-finger (2 copies) Ecl1 PF12855.2 EIW87168.1 - 0.13 11.5 13.6 3.7 6.9 0.0 5.1 5 0 0 5 5 5 0 Life-span regulatory factor zf-H2C2_2 PF13465.1 EIW87168.1 - 0.17 12.2 36.5 1.4 9.3 0.3 8.2 8 0 0 8 8 8 0 Zinc-finger double domain zf-C2H2_6 PF13912.1 EIW87168.1 - 1.2 9.1 36.1 12 5.9 0.2 8.3 8 0 0 8 8 8 0 C2H2-type zinc finger C1_4 PF07975.7 EIW87168.1 - 2.9 7.9 27.6 14 5.7 1.6 5.0 3 2 0 4 4 4 0 TFIIH C1-like domain SprT-like PF10263.4 EIW87168.1 - 6.1 6.4 19.5 0.66 9.6 0.5 2.7 1 1 0 2 2 2 0 SprT-like family zf-C2H2_4 PF13894.1 EIW87169.1 - 1.2e-17 62.8 38.5 0.019 15.2 0.1 8.3 8 0 0 8 8 8 7 C2H2-type zinc finger zf-C2H2 PF00096.21 EIW87169.1 - 6.5e-16 57.6 39.6 0.012 15.9 0.6 8.2 8 0 0 8 8 8 5 Zinc finger, C2H2 type zf-met PF12874.2 EIW87169.1 - 2.6e-12 46.4 21.3 2.4e-05 24.3 0.4 7.0 7 0 0 7 7 7 3 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EIW87169.1 - 1.4e-11 44.1 37.5 0.00029 20.8 1.0 7.7 8 0 0 8 8 8 5 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EIW87169.1 - 1.4e-08 34.7 26.4 7.5e-05 22.7 4.6 5.3 2 2 4 6 6 6 2 C2H2 type zinc-finger (2 copies) zf-CCHC_6 PF15288.1 EIW87169.1 - 0.15 11.7 2.5 0.97 9.1 0.4 2.6 2 0 0 2 2 2 0 Zinc knuckle zf-H2C2_2 PF13465.1 EIW87169.1 - 4.4 7.7 29.9 6.3 7.2 0.0 6.6 7 0 0 7 7 7 0 Zinc-finger double domain C1_4 PF07975.7 EIW87169.1 - 9.4 6.3 26.5 1.5 8.8 1.2 5.0 2 2 3 5 5 5 0 TFIIH C1-like domain EF-hand_1 PF00036.27 EIW87170.1 - 1.3e-27 92.9 16.7 4.7e-09 34.9 0.1 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EIW87170.1 - 9.9e-26 89.6 14.7 1.9e-13 50.3 1.6 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EIW87170.1 - 1.6e-23 80.3 14.7 1.8e-08 33.5 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EIW87170.1 - 8.9e-18 63.6 17.0 6.6e-08 32.0 1.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EIW87170.1 - 3.4e-16 57.7 12.9 1.9e-05 23.7 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 EIW87170.1 - 7e-10 38.6 0.7 0.001 18.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EIW87170.1 - 4.5e-09 35.9 7.3 0.00022 20.8 0.1 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EIW87170.1 - 0.019 14.9 3.7 0.29 11.1 0.2 2.2 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DUF3164 PF11363.3 EIW87170.1 - 0.021 14.2 0.5 1.2 8.5 0.0 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF3164) Caleosin PF05042.8 EIW87170.1 - 0.022 14.3 0.1 0.47 9.9 0.0 2.3 2 1 0 2 2 2 0 Caleosin related protein DUF1059 PF06348.6 EIW87170.1 - 0.051 13.4 0.3 0.54 10.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1059) Adaptin_binding PF10199.4 EIW87170.1 - 0.06 13.6 1.6 0.057 13.6 0.4 1.4 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DUF1636 PF07845.6 EIW87170.1 - 0.082 13.1 0.0 3.5 7.9 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1636) EF-hand_like PF09279.6 EIW87170.1 - 0.86 9.6 4.9 1.9 8.5 0.5 2.6 2 1 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like MgtE_N PF03448.12 EIW87170.1 - 1.8 8.9 6.3 0.51 10.6 1.1 2.3 2 1 1 3 3 3 0 MgtE intracellular N domain Con-6 PF10346.4 EIW87172.1 - 6.8e-35 118.1 5.6 2.9e-17 61.7 0.4 2.1 2 0 0 2 2 2 2 Conidiation protein 6 Acp26Ab PF05777.7 EIW87172.1 - 0.12 12.7 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 Drosophila accessory gland-specific peptide 26Ab (Acp26Ab) TPR_9 PF13371.1 EIW87174.1 - 0.0017 18.2 1.6 0.0078 16.0 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat NST1 PF13945.1 EIW87174.1 - 0.64 10.0 8.4 0.4 10.7 2.1 2.2 2 0 0 2 2 2 0 Salt tolerance down-regulator DUF3140 PF11338.3 EIW87175.1 - 1.6e-17 63.4 0.1 2.2e-17 62.9 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3140) DUF365 PF04033.7 EIW87175.1 - 0.013 15.4 0.2 0.018 15.0 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF365) DIL PF01843.14 EIW87175.1 - 0.11 12.4 0.0 0.13 12.1 0.0 1.3 1 1 0 1 1 1 0 DIL domain Cu_amine_oxid PF01179.15 EIW87176.1 - 1.2e-149 498.5 0.0 1.4e-149 498.3 0.0 1.0 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EIW87176.1 - 6.6e-15 55.0 0.0 1.3e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EIW87176.1 - 1.7e-07 31.2 0.0 5.8e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Yae1_N PF09811.4 EIW87177.1 - 2.5e-11 42.8 5.0 4.1e-11 42.2 3.5 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal BTB_2 PF02214.17 EIW87178.1 - 7.7e-05 22.8 0.0 0.0023 18.0 0.0 2.5 2 0 0 2 2 2 1 BTB/POZ domain Chitin_synth_2 PF03142.10 EIW87179.1 - 2e-276 917.5 0.0 2.8e-276 917.0 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EIW87179.1 - 2e-15 57.0 0.4 5.3e-15 55.6 0.3 1.8 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EIW87179.1 - 1.7e-10 41.0 0.0 8.6e-10 38.7 0.0 2.2 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EIW87179.1 - 0.0071 15.6 0.1 0.24 10.6 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 21 Nop10p PF04135.7 EIW87180.1 - 7.6e-21 73.5 0.1 8.9e-21 73.3 0.1 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Dus PF01207.12 EIW87181.1 - 8e-44 149.7 0.0 1.1e-43 149.2 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Oxysterol_BP PF01237.13 EIW87181.1 - 0.0073 14.8 0.7 0.01 14.3 0.5 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein CPSase_L_D2 PF02786.12 EIW87182.1 - 4.7e-74 248.2 0.1 1e-73 247.0 0.0 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EIW87182.1 - 3e-44 149.6 0.0 7.7e-44 148.3 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EIW87182.1 - 7e-32 109.6 0.0 5.2e-31 106.8 0.0 2.3 1 1 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EIW87182.1 - 1.3e-14 53.5 4.4 3e-14 52.4 3.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EIW87182.1 - 1.6e-14 54.0 0.0 3.2e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EIW87182.1 - 3.2e-14 52.4 0.0 1e-13 50.7 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EIW87182.1 - 1.4e-10 40.8 0.0 2.9e-10 39.8 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EIW87182.1 - 3.1e-08 33.1 0.0 7.3e-08 31.9 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EIW87182.1 - 6.1e-06 25.8 0.8 0.021 14.4 0.1 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like RimK PF08443.6 EIW87182.1 - 0.00022 20.7 0.0 0.0005 19.5 0.0 1.5 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EIW87182.1 - 0.0039 17.0 0.0 0.0066 16.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 EIW87182.1 - 0.006 16.1 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Toxin_59 PF15537.1 EIW87182.1 - 0.0095 16.0 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 1 Putative toxin 59 HlyD_3 PF13437.1 EIW87182.1 - 0.013 15.8 0.2 2.3 8.5 0.0 2.8 2 0 0 2 2 2 0 HlyD family secretion protein WEMBL PF05701.6 EIW87184.1 - 0.014 13.9 1.1 0.02 13.3 0.7 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light NPV_P10 PF05531.7 EIW87184.1 - 0.036 14.3 0.8 0.33 11.2 0.1 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein HNH_2 PF13391.1 EIW87187.1 - 0.055 13.2 0.1 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 HNH endonuclease Vps51 PF08700.6 EIW87188.1 - 1.3e-15 57.0 0.3 2.5e-15 56.0 0.2 1.5 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.6 EIW87188.1 - 4.8e-07 29.7 0.5 1e-06 28.6 0.4 1.5 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Nuf2 PF03800.9 EIW87189.1 - 1.3e-29 103.0 0.1 3e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 Nuf2 family Seryl_tRNA_N PF02403.17 EIW87189.1 - 0.0022 18.0 31.2 0.062 13.3 1.9 4.1 2 1 2 4 4 4 2 Seryl-tRNA synthetase N-terminal domain BLOC1_2 PF10046.4 EIW87189.1 - 0.062 13.4 0.7 0.062 13.4 0.5 4.1 3 2 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6 PF04111.7 EIW87189.1 - 0.063 12.3 32.9 0.051 12.6 1.5 3.1 1 1 1 3 3 3 0 Autophagy protein Apg6 NYD-SP28_assoc PF14775.1 EIW87189.1 - 0.12 12.0 3.9 0.93 9.2 0.3 3.3 2 1 0 2 2 2 0 Sperm tail C-terminal domain HALZ PF02183.13 EIW87189.1 - 0.35 10.6 6.0 3.4 7.4 0.2 4.0 3 1 1 4 4 4 0 Homeobox associated leucine zipper GAS PF13851.1 EIW87189.1 - 0.66 9.1 29.8 0.2 10.8 7.7 3.7 2 2 2 4 4 4 0 Growth-arrest specific micro-tubule binding DUF948 PF06103.6 EIW87189.1 - 2.7 7.8 8.1 21 5.0 0.1 4.3 4 1 1 5 5 5 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.6 EIW87189.1 - 3.4 6.2 25.8 1.8 7.1 12.1 2.9 1 1 2 3 3 3 0 Spc7 kinetochore protein Filament PF00038.16 EIW87189.1 - 3.6 6.9 35.2 1 8.7 2.5 3.7 1 1 1 2 2 2 0 Intermediate filament protein Sel1 PF08238.7 EIW87190.1 - 3.3e-45 151.5 25.1 1.9e-08 34.6 0.2 8.3 8 0 0 8 8 8 7 Sel1 repeat DnaJ PF00226.26 EIW87191.1 - 1.5e-11 43.8 0.4 3.9e-11 42.5 0.3 1.7 1 1 0 1 1 1 1 DnaJ domain zf-CSL PF05207.8 EIW87191.1 - 7.8e-10 38.1 0.6 1.2e-09 37.5 0.4 1.3 1 0 0 1 1 1 1 CSL zinc finger DUF3133 PF11331.3 EIW87191.1 - 0.048 13.2 0.2 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) DNA_methylase PF00145.12 EIW87192.1 - 2e-40 138.9 0.0 1.7e-39 135.9 0.0 2.5 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 EIW87192.1 - 3.6e-14 52.5 0.0 9.2e-08 31.8 0.0 2.7 2 0 0 2 2 2 2 BAH domain DNMT1-RFD PF12047.3 EIW87192.1 - 6.5e-13 48.6 0.1 1.6e-12 47.3 0.0 1.6 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain Methyltransf_26 PF13659.1 EIW87192.1 - 0.00015 21.7 0.0 0.00043 20.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EIW87192.1 - 0.00069 19.2 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Cons_hypoth95 PF03602.10 EIW87192.1 - 0.14 11.5 0.0 0.37 10.1 0.0 1.6 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Pkinase PF00069.20 EIW87193.1 - 1.3e-71 240.7 0.0 1.6e-71 240.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW87193.1 - 1.8e-31 109.1 0.0 2.3e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIW87193.1 - 0.00031 19.8 0.0 0.00089 18.3 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW87193.1 - 0.00055 19.7 0.0 0.0009 19.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EIW87193.1 - 0.00096 18.1 0.0 0.02 13.8 0.0 2.1 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EIW87193.1 - 0.016 14.5 0.1 0.05 12.9 0.0 1.8 2 0 0 2 2 2 0 RIO1 family NAD_binding_1 PF00175.16 EIW87194.1 - 4.5e-26 91.5 0.0 7.1e-26 90.9 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EIW87194.1 - 6e-17 61.5 0.0 1.1e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EIW87194.1 - 2.7e-07 30.6 0.0 7.9e-05 22.5 0.0 2.4 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EIW87194.1 - 0.00086 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain UCH PF00443.24 EIW87195.1 - 3.6e-45 154.1 0.3 5.7e-45 153.5 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EIW87195.1 - 1.7e-22 78.5 0.4 1.2e-18 66.2 0.0 2.5 2 0 0 2 2 2 2 A repeated domain in UCH-protein UCH_1 PF13423.1 EIW87195.1 - 1.8e-14 53.8 5.6 5.7e-09 35.8 2.0 3.0 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase IncA PF04156.9 EIW87195.1 - 0.054 13.0 8.5 0.1 12.2 5.9 1.4 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 EIW87195.1 - 0.16 10.3 4.1 0.23 9.8 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) HALZ PF02183.13 EIW87195.1 - 0.16 11.6 1.9 0.37 10.5 1.3 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper Prefoldin_2 PF01920.15 EIW87195.1 - 3.3 7.5 10.4 2.6 7.8 0.5 2.6 2 0 0 2 2 2 0 Prefoldin subunit TBCA PF02970.11 EIW87196.1 - 0.014 15.4 0.2 1.7 8.7 0.0 2.1 1 1 1 2 2 2 0 Tubulin binding cofactor A UPF0184 PF03670.8 EIW87196.1 - 0.019 15.1 2.4 0.021 15.0 1.1 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0184) NPV_P10 PF05531.7 EIW87200.1 - 0.19 11.9 1.4 1.3 9.2 0.1 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF2396 PF09654.5 EIW87201.1 - 0.14 12.1 1.3 5.9 6.8 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2396) UCH PF00443.24 EIW87202.1 - 8e-52 175.9 0.4 8.9e-52 175.8 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EIW87202.1 - 2.7e-29 102.5 0.2 3.1e-29 102.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EIW87202.1 - 0.68 9.1 4.1 1.4 8.1 1.4 2.3 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase MOSC_N PF03476.11 EIW87203.1 - 1.9e-14 53.3 0.0 3.2e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EIW87203.1 - 2.2e-09 36.8 0.2 0.00017 21.0 0.0 2.4 2 0 0 2 2 2 2 MOSC domain Rotamase PF00639.16 EIW87204.1 - 3.1e-25 88.7 0.1 4.3e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EIW87204.1 - 1.3e-17 64.1 0.0 1.7e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EIW87204.1 - 2.1e-07 30.6 0.3 2.1e-07 30.6 0.2 1.7 2 0 0 2 2 2 1 WW domain Rotamase_2 PF13145.1 EIW87204.1 - 4.6e-06 27.2 0.0 6.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain NSP2_assoc PF14758.1 EIW87204.1 - 0.093 12.8 0.0 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Non-essential region of nsp2 of arterivirus polyprotein DUF4246 PF14033.1 EIW87205.1 - 2.7e-79 267.1 0.0 4.3e-79 266.4 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF4246) efThoc1 PF11957.3 EIW87206.1 - 2.5e-95 319.8 0.1 3.4e-90 302.8 0.0 2.1 2 0 0 2 2 2 2 THO complex subunit 1 transcription elongation factor Epimerase PF01370.16 EIW87206.1 - 1.1e-32 113.3 0.0 2.6e-32 112.1 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EIW87206.1 - 5.2e-24 83.9 0.0 1.2e-23 82.7 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit RmlD_sub_bind PF04321.12 EIW87206.1 - 8.9e-08 31.3 0.0 2.2e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EIW87206.1 - 6.1e-06 25.1 0.0 1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EIW87206.1 - 0.00062 18.7 0.0 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EIW87206.1 - 0.0015 17.5 0.0 0.0033 16.3 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein DUF605 PF04652.11 EIW87206.1 - 0.52 9.6 12.0 0.86 8.9 8.3 1.4 1 0 0 1 1 1 0 Vta1 like Peptidase_A4 PF01828.12 EIW87207.1 - 1.2e-64 217.2 17.8 1.4e-64 216.9 12.4 1.1 1 0 0 1 1 1 1 Peptidase A4 family p450 PF00067.17 EIW87211.1 - 2.6e-05 22.9 0.0 2.6e-05 22.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TauD PF02668.11 EIW87212.1 - 1e-38 133.5 0.2 1.5e-38 133.0 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TauD PF02668.11 EIW87213.1 - 2.9e-51 174.6 0.1 3.9e-51 174.2 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family zf-C2H2 PF00096.21 EIW87214.1 - 1.7e-11 43.7 14.2 1.4e-06 28.2 1.5 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EIW87214.1 - 1.6e-08 34.3 12.4 0.00027 21.0 1.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EIW87214.1 - 2.9e-05 24.1 7.2 2.9e-05 24.1 5.0 3.2 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_6 PF13912.1 EIW87214.1 - 0.01 15.6 0.8 0.01 15.6 0.6 2.5 2 1 0 2 2 2 0 C2H2-type zinc finger Ogr_Delta PF04606.7 EIW87214.1 - 0.013 15.1 1.3 0.05 13.2 0.1 2.1 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger zf-C2H2_jaz PF12171.3 EIW87214.1 - 0.066 13.3 4.6 0.34 11.1 0.1 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EIW87214.1 - 0.23 11.7 0.1 0.23 11.7 0.1 2.7 3 0 0 3 3 3 0 Zinc-finger of C2H2 type DUF3729 PF12526.3 EIW87214.1 - 0.31 12.4 2.9 0.28 12.5 0.7 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3729) zf-C2H2 PF00096.21 EIW87216.1 - 5.3e-10 39.0 12.5 2.5e-05 24.3 0.9 2.3 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EIW87216.1 - 9.3e-09 35.1 15.9 2.8e-07 30.4 4.0 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EIW87216.1 - 3.6e-08 33.1 9.6 0.0014 18.8 1.5 2.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EIW87216.1 - 0.0021 17.8 1.9 0.0021 17.8 1.3 2.8 5 1 0 5 5 5 1 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EIW87216.1 - 0.11 12.6 1.5 0.11 12.6 1.1 2.8 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EIW87216.1 - 0.28 10.9 5.4 5.4 6.8 0.2 2.4 1 1 1 2 2 2 0 BED zinc finger CHORD PF04968.7 EIW87216.1 - 0.94 9.7 5.9 1.6 9.0 0.5 2.2 1 1 1 2 2 2 0 CHORD Y_phosphatase PF00102.22 EIW87217.1 - 1.2e-39 136.0 0.0 5.1e-24 84.9 0.1 2.9 2 1 0 2 2 2 2 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EIW87217.1 - 5.4e-06 26.5 0.0 1.1e-05 25.5 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 EIW87217.1 - 0.002 17.7 0.0 0.0039 16.7 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EIW87217.1 - 0.002 18.3 0.0 0.0042 17.3 0.0 1.6 1 1 0 1 1 1 1 Tyrosine phosphatase family ADH_zinc_N PF00107.21 EIW87218.1 - 1.2e-32 112.1 0.0 2e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW87218.1 - 3.7e-19 69.8 0.0 1e-18 68.4 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW87218.1 - 2e-06 27.5 0.0 1.4e-05 24.8 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 EIW87218.1 - 0.013 15.4 0.1 0.023 14.7 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain SIS_2 PF13580.1 EIW87218.1 - 0.073 12.7 0.1 0.16 11.6 0.1 1.6 1 0 0 1 1 1 0 SIS domain ADH_zinc_N PF00107.21 EIW87219.1 - 5.6e-33 113.2 0.2 1e-32 112.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EIW87219.1 - 2.2e-19 70.5 0.1 5.9e-19 69.2 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EIW87219.1 - 4.2e-07 29.7 0.0 1e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 EIW87219.1 - 0.058 13.4 0.1 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain SIS_2 PF13580.1 EIW87219.1 - 0.1 12.3 0.1 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 SIS domain p450 PF00067.17 EIW87220.1 - 4.4e-80 269.4 0.0 5.2e-80 269.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_47 PF01532.15 EIW87221.1 - 2.3e-152 507.7 0.0 2.7e-152 507.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Rod-binding PF10135.4 EIW87221.1 - 1.6 8.8 4.0 0.58 10.1 0.5 2.0 2 0 0 2 2 2 0 Rod binding protein BTB PF00651.26 EIW87223.1 - 1.2e-07 31.6 0.0 2.7e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EIW87224.1 - 1.1e-07 31.7 0.0 3.3e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EIW87225.1 - 7.7e-11 41.9 0.0 2.2e-10 40.4 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain YaeQ PF07152.7 EIW87225.1 - 0.096 12.0 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 YaeQ protein Enolase_C PF00113.17 EIW87226.1 - 3.1e-146 485.9 0.1 4.4e-146 485.4 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EIW87226.1 - 1.4e-55 186.8 0.1 2.3e-55 186.1 0.1 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.1 EIW87226.1 - 2.4e-05 24.2 0.0 5.9e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.6 EIW87226.1 - 0.0012 17.7 0.4 0.0024 16.8 0.1 1.6 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 EIW87226.1 - 0.006 17.0 0.0 0.013 16.0 0.0 1.6 1 1 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain NGP1NT PF08153.7 EIW87227.1 - 1e-46 158.1 0.0 2.5e-46 156.8 0.0 1.7 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EIW87227.1 - 7.9e-20 70.9 0.1 5.4e-16 58.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EIW87227.1 - 2.3e-05 23.7 0.1 0.00016 21.0 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EIW87227.1 - 0.00017 20.7 0.0 0.00033 19.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EIW87227.1 - 0.00042 19.7 0.3 0.12 11.8 0.0 2.8 1 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Arf PF00025.16 EIW87227.1 - 0.02 14.1 0.0 0.3 10.3 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.18 EIW87227.1 - 0.045 13.5 6.0 2.8 7.7 0.1 3.8 3 1 1 4 4 4 0 Dynamin family Ribosomal_S15 PF00312.17 EIW87228.1 - 2.2e-18 65.7 2.5 3.8e-18 65.0 0.8 2.1 1 1 1 2 2 2 1 Ribosomal protein S15 DUF1566 PF07603.6 EIW87229.1 - 0.0057 16.3 1.0 0.012 15.3 0.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1566) F-box-like PF12937.2 EIW87229.1 - 0.0075 15.9 0.1 0.022 14.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW87229.1 - 0.0097 15.5 0.2 0.037 13.7 0.1 2.0 1 0 0 1 1 1 1 F-box domain Ion_trans_N PF08412.5 EIW87229.1 - 0.16 11.2 0.0 10 5.5 0.0 2.3 2 0 0 2 2 2 0 Ion transport protein N-terminal PqqD PF05402.7 EIW87230.1 - 0.0036 17.2 0.2 0.008 16.1 0.1 1.5 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) Sugar_tr PF00083.19 EIW87231.1 - 2.9e-120 401.9 21.1 3.3e-120 401.7 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW87231.1 - 2.5e-16 59.3 38.7 2.3e-15 56.1 19.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily F-box-like PF12937.2 EIW87232.1 - 5.1e-06 26.1 0.1 1.1e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like IBN_N PF03810.14 EIW87234.1 - 1.2e-10 41.1 0.0 7.9e-09 35.3 0.0 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.5 EIW87234.1 - 6.7e-07 28.1 0.3 6.7e-07 28.1 0.2 2.2 3 0 0 3 3 3 1 Cse1 HEAT_2 PF13646.1 EIW87234.1 - 7.8e-05 22.8 1.4 0.18 12.0 0.0 4.8 3 2 0 4 4 4 1 HEAT repeats Adaptin_N PF01602.15 EIW87234.1 - 0.00023 19.6 0.5 0.089 11.0 0.0 2.8 2 1 0 2 2 2 2 Adaptin N terminal region HEAT PF02985.17 EIW87234.1 - 0.0019 18.1 0.1 0.19 11.9 0.0 4.2 3 0 0 3 3 3 1 HEAT repeat ParcG PF10274.4 EIW87234.1 - 0.0043 16.9 0.5 2.2 8.1 0.0 3.4 5 0 0 5 5 5 1 Parkin co-regulated protein Xpo1 PF08389.7 EIW87234.1 - 0.011 15.6 2.8 0.045 13.6 0.0 3.7 5 1 0 5 5 5 0 Exportin 1-like protein DUF4441 PF14536.1 EIW87234.1 - 0.049 13.6 0.5 0.35 10.8 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) zf-MYND PF01753.13 EIW87235.1 - 1.6e-07 31.0 14.2 3.5e-07 29.9 9.9 1.6 1 0 0 1 1 1 1 MYND finger PqqD PF05402.7 EIW87235.1 - 0.0014 18.5 0.4 0.003 17.5 0.3 1.5 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) LTV PF04180.9 EIW87235.1 - 0.039 13.4 3.6 0.06 12.8 2.5 1.2 1 0 0 1 1 1 0 Low temperature viability protein DZR PF12773.2 EIW87235.1 - 7.4 6.4 11.6 14 5.6 6.8 2.4 2 1 0 2 2 2 0 Double zinc ribbon zf-MYND PF01753.13 EIW87236.1 - 8.8e-10 38.2 12.6 3.1e-09 36.5 8.7 2.0 1 0 0 1 1 1 1 MYND finger TFIIS_C PF01096.13 EIW87236.1 - 0.014 15.0 3.0 0.022 14.4 1.0 2.2 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) PqqD PF05402.7 EIW87236.1 - 0.073 13.0 0.1 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) Trm112p PF03966.11 EIW87236.1 - 0.097 13.0 1.1 16 5.9 0.0 2.6 2 0 0 2 2 2 0 Trm112p-like protein Inositol_P PF00459.20 EIW87239.1 - 6.2e-67 225.7 0.0 6.8e-67 225.6 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family 3D PF06725.6 EIW87239.1 - 0.088 12.7 0.0 4.2 7.4 0.0 2.5 2 0 0 2 2 2 0 3D domain Proteasome PF00227.21 EIW87240.1 - 3.2e-56 189.6 0.1 4.1e-56 189.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EIW87240.1 - 2.1e-14 52.5 0.0 3.6e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature G-alpha PF00503.15 EIW87241.1 - 2.1e-121 405.2 0.0 2.8e-121 404.8 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EIW87241.1 - 4.9e-13 48.6 0.1 5.5e-09 35.4 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family AAA_29 PF13555.1 EIW87241.1 - 0.0027 17.1 0.1 0.0067 15.9 0.0 1.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EIW87241.1 - 0.0055 16.1 0.0 0.12 11.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Ras PF00071.17 EIW87241.1 - 0.0067 15.8 0.0 1.1 8.6 0.0 2.5 2 1 0 2 2 2 2 Ras family Gtr1_RagA PF04670.7 EIW87241.1 - 0.037 13.1 0.9 5.1 6.1 0.1 2.4 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region DAP3 PF10236.4 EIW87241.1 - 0.045 12.6 0.1 0.072 12.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Miro PF08477.8 EIW87241.1 - 0.091 13.2 0.0 0.79 10.2 0.0 2.5 3 0 0 3 3 3 0 Miro-like protein PTS_EIIC PF02378.13 EIW87242.1 - 0.39 9.4 1.1 0.57 8.9 0.8 1.1 1 0 0 1 1 1 0 Phosphotransferase system, EIIC EphA2_TM PF14575.1 EIW87242.1 - 0.39 11.1 0.0 0.86 10.0 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RepB PF07506.6 EIW87242.1 - 0.51 10.1 1.6 0.83 9.4 1.1 1.2 1 0 0 1 1 1 0 RepB plasmid partitioning protein Sugar_tr PF00083.19 EIW87244.1 - 3.7e-117 391.6 19.5 4.6e-117 391.3 13.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EIW87244.1 - 1.1e-17 63.8 39.1 7.6e-13 47.8 9.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Flavi_NS4A PF01350.12 EIW87244.1 - 0.32 10.5 4.3 0.45 10.0 1.2 2.2 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A Ribonuc_L-PSP PF01042.16 EIW87245.1 - 2.2e-43 146.8 0.0 2.4e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DASH_Ask1 PF08655.5 EIW87246.1 - 3.9e-21 74.6 0.1 7.9e-21 73.6 0.1 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 zf-MYND PF01753.13 EIW87248.1 - 3.1e-10 39.7 10.8 6.1e-10 38.8 7.5 1.5 1 0 0 1 1 1 1 MYND finger PqqD PF05402.7 EIW87248.1 - 0.0024 17.8 0.1 0.0046 16.9 0.1 1.5 1 0 0 1 1 1 1 Coenzyme PQQ synthesis protein D (PqqD) DZR PF12773.2 EIW87248.1 - 0.16 11.8 4.0 0.43 10.4 2.8 1.7 1 0 0 1 1 1 0 Double zinc ribbon NinF PF05810.7 EIW87248.1 - 0.21 11.3 2.3 0.7 9.7 1.6 1.9 1 0 0 1 1 1 0 NinF protein CAP18_C PF12153.3 EIW87248.1 - 4.9 6.8 5.1 0.82 9.3 0.4 2.1 2 0 0 2 2 2 0 LPS binding domain of CAP18 (C terminal) zf-MYND PF01753.13 EIW87249.1 - 1.9e-10 40.4 22.7 1e-09 38.0 9.0 2.9 2 0 0 2 2 2 2 MYND finger PqqD PF05402.7 EIW87249.1 - 0.024 14.6 0.1 0.053 13.5 0.1 1.6 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) CbiK PF06180.6 EIW87249.1 - 0.1 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Cobalt chelatase (CbiK) DZR PF12773.2 EIW87249.1 - 1.3 8.9 18.3 1.1 9.1 4.0 3.2 3 0 0 3 3 3 0 Double zinc ribbon zf-MYND PF01753.13 EIW87250.1 - 0.009 15.8 0.9 0.009 15.8 0.6 2.7 2 0 0 2 2 2 1 MYND finger C1_3 PF07649.7 EIW87250.1 - 0.01 15.8 2.1 0.01 15.8 1.4 2.2 2 0 0 2 2 2 0 C1-like domain DUF1187 PF06688.6 EIW87250.1 - 0.084 13.0 0.1 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1187) PHF5 PF03660.9 EIW87250.1 - 0.23 11.5 3.3 0.59 10.2 0.9 2.3 2 0 0 2 2 2 0 PHF5-like protein DZR PF12773.2 EIW87250.1 - 0.57 10.0 6.7 0.25 11.1 2.3 2.2 2 0 0 2 2 2 0 Double zinc ribbon C1_2 PF03107.11 EIW87250.1 - 5.7 7.1 8.2 1.2 9.2 1.8 2.8 2 0 0 2 2 2 0 C1 domain zf-MYND PF01753.13 EIW87251.1 - 2.2e-07 30.6 15.4 5.4e-07 29.3 10.7 1.7 1 0 0 1 1 1 1 MYND finger zinc_ribbon_2 PF13240.1 EIW87251.1 - 0.5 9.9 9.0 3 7.4 0.6 3.1 3 0 0 3 3 3 0 zinc-ribbon domain DZR PF12773.2 EIW87251.1 - 0.71 9.7 8.3 0.75 9.6 4.3 1.9 1 1 1 2 2 2 0 Double zinc ribbon zf-MYND PF01753.13 EIW87252.1 - 1.5e-07 31.1 10.4 3.6e-07 29.9 7.2 1.7 1 0 0 1 1 1 1 MYND finger Ecl1 PF12855.2 EIW87252.1 - 0.0013 17.9 2.5 0.0032 16.7 1.7 1.6 1 0 0 1 1 1 1 Life-span regulatory factor C1_3 PF07649.7 EIW87252.1 - 0.18 11.8 5.3 0.48 10.4 3.7 1.7 1 0 0 1 1 1 0 C1-like domain PLATZ PF04640.9 EIW87252.1 - 0.79 9.9 8.0 49 4.2 5.5 2.4 1 1 0 1 1 1 0 PLATZ transcription factor C1_2 PF03107.11 EIW87252.1 - 5 7.3 8.1 1.5 8.9 2.0 2.6 2 0 0 2 2 2 0 C1 domain CorA PF01544.13 EIW87253.1 - 3.5e-33 114.8 12.0 1.1e-21 77.1 1.4 3.2 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein HAD_2 PF13419.1 EIW87254.1 - 4.3e-26 92.1 0.1 5.1e-26 91.9 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIW87254.1 - 0.00069 20.0 0.0 0.024 15.0 0.0 2.5 1 1 2 3 3 3 1 haloacid dehalogenase-like hydrolase p450 PF00067.17 EIW87255.1 - 1.5e-61 208.3 0.0 2e-61 207.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 CRAL_TRIO PF00650.15 EIW87256.1 - 2.2e-37 128.0 0.0 3.1e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EIW87256.1 - 0.00096 19.0 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EIW87256.1 - 0.018 15.1 0.0 0.043 13.9 0.0 1.7 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain GRAM PF02893.15 EIW87259.1 - 1.6e-16 59.5 0.0 2.9e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 GRAM domain CENP-B_dimeris PF09026.5 EIW87259.1 - 0.2 11.9 3.6 0.41 10.9 2.5 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain NDUFA12 PF05071.11 EIW87260.1 - 4.2e-12 46.4 0.7 4.2e-12 46.4 0.5 2.2 1 1 1 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 HAD_2 PF13419.1 EIW87261.1 - 1.1e-24 87.5 0.0 1.4e-24 87.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EIW87261.1 - 0.065 13.6 0.0 0.19 12.1 0.0 1.7 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EIW87261.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like zf-MYND PF01753.13 EIW87262.1 - 7.9e-09 35.2 14.6 1.8e-08 34.0 10.1 1.7 1 0 0 1 1 1 1 MYND finger PqqD PF05402.7 EIW87262.1 - 0.029 14.3 0.2 0.062 13.3 0.2 1.5 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) WHG PF13305.1 EIW87262.1 - 0.077 13.5 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 WHG domain PLATZ PF04640.9 EIW87262.1 - 5.4 7.2 8.5 79 3.5 6.0 2.7 2 1 0 2 2 2 0 PLATZ transcription factor DUF4218 PF13960.1 EIW87263.1 - 0.01 15.2 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4218) TIP49 PF06068.8 EIW87263.1 - 0.11 11.2 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 TIP49 C-terminus PIN_3 PF13470.1 EIW87264.1 - 0.086 13.5 0.4 0.13 12.9 0.3 1.4 1 0 0 1 1 1 0 PIN domain Pkinase PF00069.20 EIW87265.1 - 6e-60 202.5 0.0 1.2e-35 122.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW87265.1 - 5.6e-26 91.1 0.0 2.3e-15 56.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EIW87265.1 - 5.7e-06 26.7 5.7 3.2e-05 24.3 3.9 2.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.9 EIW87265.1 - 0.0018 17.4 0.0 0.0033 16.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EIW87265.1 - 0.024 13.6 0.0 0.86 8.5 0.0 2.5 3 0 0 3 3 3 0 Kinase-like Hs1pro-1_C PF07014.7 EIW87265.1 - 0.2 10.9 0.0 0.34 10.1 0.0 1.3 1 0 0 1 1 1 0 Hs1pro-1 protein C-terminus Pyridox_oxase_2 PF12766.2 EIW87266.1 - 6.4e-21 74.5 0.1 1.6e-20 73.2 0.0 1.6 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_oxidase PF01243.15 EIW87266.1 - 0.0065 16.4 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase CorA PF01544.13 EIW87267.1 - 3.3e-30 105.1 12.4 9.6e-23 80.6 1.5 3.1 3 0 0 3 3 3 3 CorA-like Mg2+ transporter protein zf-MYND PF01753.13 EIW87268.1 - 1.2e-06 28.3 12.8 2.9e-06 27.0 8.8 1.7 1 0 0 1 1 1 1 MYND finger TGT_C1 PF14809.1 EIW87268.1 - 0.014 15.1 0.0 0.064 13.0 0.0 2.0 2 0 0 2 2 2 0 C1 domain of tRNA-guanine transglycosylase dimerisation DPM2 PF07297.7 EIW87268.1 - 0.048 13.9 0.1 0.098 12.9 0.1 1.4 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PqqD PF05402.7 EIW87268.1 - 0.088 12.8 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) PLATZ PF04640.9 EIW87268.1 - 5.2 7.3 6.7 39 4.5 4.6 2.4 1 1 0 1 1 1 0 PLATZ transcription factor zf-MYND PF01753.13 EIW87269.1 - 1.9e-08 34.0 8.4 6.7e-08 32.2 5.8 2.0 1 1 0 1 1 1 1 MYND finger PqqD PF05402.7 EIW87269.1 - 0.059 13.3 0.1 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) PLATZ PF04640.9 EIW87269.1 - 1.7 8.9 7.1 15 5.9 4.9 2.3 1 1 0 1 1 1 0 PLATZ transcription factor zf-MYND PF01753.13 EIW87270.1 - 2.6e-08 33.5 13.4 7.6e-08 32.1 9.3 1.9 1 0 0 1 1 1 1 MYND finger DUF2110 PF09883.4 EIW87270.1 - 0.051 13.1 0.1 0.078 12.6 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2110) PqqD PF05402.7 EIW87270.1 - 0.084 12.8 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) ADH_N PF08240.7 EIW87271.1 - 1.2e-23 82.9 0.5 1.9e-23 82.2 0.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW87271.1 - 1.4e-17 63.4 0.0 7.5e-17 61.1 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PK_C PF02887.11 EIW87271.1 - 0.029 13.9 0.0 0.066 12.7 0.0 1.7 1 1 0 1 1 1 0 Pyruvate kinase, alpha/beta domain zf-MYND PF01753.13 EIW87272.1 - 5.8e-14 51.6 33.1 4.9e-08 32.7 6.7 2.6 2 0 0 2 2 2 2 MYND finger PqqD PF05402.7 EIW87272.1 - 0.0031 17.4 3.1 1.4 9.0 0.1 2.6 2 0 0 2 2 2 2 Coenzyme PQQ synthesis protein D (PqqD) NinF PF05810.7 EIW87272.1 - 0.21 11.4 10.5 1.5 8.7 0.3 3.3 2 1 1 3 3 3 0 NinF protein Ecl1 PF12855.2 EIW87272.1 - 0.51 9.6 17.6 0.058 12.6 0.7 2.9 2 1 0 2 2 2 0 Life-span regulatory factor PLATZ PF04640.9 EIW87272.1 - 3 8.1 16.3 0.75 10.0 0.8 3.7 3 1 0 3 3 3 0 PLATZ transcription factor C1_3 PF07649.7 EIW87272.1 - 4.4 7.4 20.1 3.4 7.7 2.2 3.6 3 0 0 3 3 3 0 C1-like domain Pkinase PF00069.20 EIW87274.1 - 2.9e-08 33.1 0.0 6.1e-08 32.1 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW87274.1 - 0.21 10.6 0.0 0.44 9.5 0.0 1.6 1 1 0 1 1 1 0 Protein tyrosine kinase TIP49 PF06068.8 EIW87275.1 - 1.8e-174 580.1 1.2 2.2e-174 579.8 0.8 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EIW87275.1 - 1.8e-09 37.9 0.2 5e-06 26.7 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EIW87275.1 - 7.1e-08 31.7 1.5 0.00012 21.2 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 EIW87275.1 - 4.4e-05 22.4 0.2 7.5e-05 21.7 0.1 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.1 EIW87275.1 - 7.9e-05 22.7 0.5 0.00056 19.9 0.1 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EIW87275.1 - 8.7e-05 22.6 0.6 0.081 13.0 0.0 2.7 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 EIW87275.1 - 0.0021 17.2 1.0 0.068 12.3 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EIW87275.1 - 0.0022 17.4 0.2 0.007 15.7 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EIW87275.1 - 0.013 15.2 0.3 4.9 6.8 0.0 3.0 2 1 1 3 3 3 0 AAA domain (dynein-related subfamily) Parvo_NS1 PF01057.12 EIW87275.1 - 0.037 12.8 0.1 0.064 12.1 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 EIW87275.1 - 0.17 11.8 0.1 0.17 11.8 0.0 2.2 3 0 0 3 3 3 0 AAA domain Ribosomal_L2_C PF03947.13 EIW87276.1 - 6.1e-49 165.1 1.1 1.1e-48 164.2 0.8 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EIW87276.1 - 6.6e-27 93.2 0.2 1.2e-26 92.4 0.1 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain Homeobox PF00046.24 EIW87277.1 - 5.5e-17 61.1 3.7 9.9e-17 60.3 2.5 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EIW87277.1 - 0.00014 21.4 0.0 0.00048 19.7 0.0 1.9 1 0 0 1 1 1 1 Homeobox KN domain Pkinase PF00069.20 EIW87278.1 - 4.6e-05 22.7 0.0 0.017 14.2 0.0 2.6 1 1 1 2 2 2 2 Protein kinase domain Pkinase PF00069.20 EIW87279.1 - 3.3e-10 39.5 0.0 5.6e-07 28.9 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EIW87279.1 - 0.00059 18.9 0.0 0.013 14.5 0.0 2.3 3 0 0 3 3 3 1 Protein tyrosine kinase AUX_IAA PF02309.11 EIW87279.1 - 0.034 13.8 0.0 0.055 13.2 0.0 1.3 1 0 0 1 1 1 0 AUX/IAA family RVT_1 PF00078.22 EIW87281.1 - 5.6e-05 22.6 0.0 5.6e-05 22.6 0.0 1.0 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_4 PF14392.1 EIW87283.1 - 0.29 10.8 0.1 0.29 10.8 0.1 3.2 3 1 1 4 4 4 0 Zinc knuckle DNA_RNApol_7kD PF03604.8 EIW87283.1 - 4 6.9 11.8 1.6 8.2 0.3 3.4 2 1 1 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Dimer_Tnp_hAT PF05699.9 EIW87284.1 - 8.4e-14 50.9 0.3 9.5e-14 50.7 0.2 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-MYND PF01753.13 EIW87285.1 - 4.5e-08 32.8 12.1 8.4e-08 31.9 8.4 1.5 1 0 0 1 1 1 1 MYND finger PqqD PF05402.7 EIW87285.1 - 0.034 14.1 0.1 0.072 13.1 0.1 1.5 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) Mss4 PF04421.8 EIW87285.1 - 0.17 11.7 1.4 5.3 6.9 0.3 2.6 1 1 1 2 2 2 0 Mss4 protein zf-MYND PF01753.13 EIW87286.1 - 1.5e-06 27.9 17.8 3e-06 26.9 12.4 1.5 1 0 0 1 1 1 1 MYND finger PqqD PF05402.7 EIW87286.1 - 0.51 10.4 2.6 1.2 9.1 1.8 1.6 1 0 0 1 1 1 0 Coenzyme PQQ synthesis protein D (PqqD) PLATZ PF04640.9 EIW87286.1 - 5.2 7.3 9.2 30 4.9 6.1 2.2 1 1 1 2 2 2 0 PLATZ transcription factor Methyltransf_16 PF10294.4 EIW87287.1 - 4.5e-18 65.2 0.0 6.4e-18 64.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EIW87287.1 - 4e-10 40.2 0.0 6.7e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EIW87287.1 - 5.3e-07 29.3 0.0 8e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EIW87287.1 - 3.8e-06 27.2 0.0 6.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EIW87287.1 - 1.1e-05 24.9 0.0 1.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EIW87287.1 - 1.1e-05 25.4 0.6 1.9e-05 24.6 0.4 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EIW87287.1 - 0.00017 21.9 0.0 0.0003 21.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EIW87287.1 - 0.00025 20.2 0.0 0.00036 19.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EIW87287.1 - 0.0022 17.5 0.0 0.0034 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EIW87287.1 - 0.016 14.9 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF938 PF06080.7 EIW87287.1 - 0.047 13.2 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_32 PF13679.1 EIW87287.1 - 0.05 13.2 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain YycC PF14174.1 EIW87288.1 - 0.16 11.6 0.2 0.33 10.6 0.0 1.7 2 0 0 2 2 2 0 YycC-like protein ADH_N PF08240.7 EIW87291.1 - 9.5e-13 47.8 0.0 5.9e-11 42.0 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EIW87291.1 - 1.6e-11 43.8 0.1 2.6e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase MBT PF02820.13 EIW87291.1 - 0.17 11.7 0.0 0.44 10.5 0.0 1.7 1 1 0 1 1 1 0 mbt repeat Polysacc_deac_1 PF01522.16 EIW87292.1 - 3.5e-05 23.4 0.3 0.00021 20.9 0.2 2.1 1 1 0 1 1 1 1 Polysaccharide deacetylase Methyltransf_20 PF12147.3 EIW87294.1 - 0.15 10.9 0.0 0.44 9.3 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase Malic_M PF03949.10 EIW87295.1 - 1.2e-76 257.6 0.0 3e-76 256.3 0.0 1.6 2 0 0 2 2 2 1 Malic enzyme, NAD binding domain malic PF00390.14 EIW87295.1 - 9.7e-58 194.7 0.0 1.4e-57 194.2 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain LysM PF01476.15 EIW87296.1 - 4.9e-15 55.1 0.0 7.5e-15 54.5 0.0 1.3 1 0 0 1 1 1 1 LysM domain MARVEL PF01284.18 EIW87297.1 - 1.3e-08 34.8 16.5 1.6e-08 34.5 11.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain VKG_Carbox PF05090.9 EIW87297.1 - 0.035 12.9 3.5 0.047 12.5 2.4 1.1 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase Herpes_UL73 PF03554.8 EIW87297.1 - 0.24 11.2 5.8 0.38 10.5 0.6 2.4 2 0 0 2 2 2 0 UL73 viral envelope glycoprotein DUF2842 PF11003.3 EIW87297.1 - 4.6 7.1 8.2 11 5.9 0.2 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2842) F-box-like PF12937.2 EIW87298.1 - 4.8e-05 22.9 0.4 0.00015 21.4 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EIW87300.1 - 0.0012 18.4 4.8 0.0019 17.8 0.2 3.0 4 0 0 4 4 4 1 F-box domain F-box-like PF12937.2 EIW87300.1 - 0.0052 16.4 0.2 0.013 15.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like zf-HYPF PF07503.7 EIW87300.1 - 0.017 14.5 0.6 0.05 13.0 0.4 1.8 1 0 0 1 1 1 0 HypF finger FTA4 PF13093.1 EIW87300.1 - 0.059 12.7 0.9 0.11 11.9 0.6 1.4 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 ArfGap PF01412.13 EIW87300.1 - 0.88 9.3 6.3 7.6 6.3 0.1 3.7 3 0 0 3 3 3 0 Putative GTPase activating protein for Arf zf-MYND PF01753.13 EIW87301.1 - 0.00029 20.6 13.1 0.00066 19.4 9.1 1.7 1 0 0 1 1 1 1 MYND finger PqqD PF05402.7 EIW87301.1 - 0.028 14.4 1.1 0.09 12.8 0.3 2.1 2 0 0 2 2 2 0 Coenzyme PQQ synthesis protein D (PqqD) zf-MYND PF01753.13 EIW87302.1 - 0.00066 19.5 20.6 0.00066 19.5 14.3 2.4 2 0 0 2 2 2 1 MYND finger F-box PF00646.28 EIW87303.1 - 0.0009 18.8 0.2 0.0009 18.8 0.2 3.1 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 EIW87303.1 - 0.0024 17.5 0.1 0.0024 17.5 0.0 2.5 3 0 0 3 3 3 1 F-box-like RRM_1 PF00076.17 EIW87304.1 - 1.5e-26 91.7 0.2 2.4e-13 49.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW87304.1 - 5.8e-21 74.1 0.0 3.4e-09 36.3 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW87304.1 - 2.2e-18 65.9 0.2 1.8e-08 34.2 0.0 2.6 2 1 1 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EIW87304.1 - 2.6e-05 23.8 0.0 0.024 14.3 0.0 2.4 2 0 0 2 2 2 2 Limkain b1 Calcipressin PF04847.7 EIW87304.1 - 0.00032 20.3 0.5 0.014 15.0 0.0 2.4 2 1 0 2 2 2 1 Calcipressin RRM_3 PF08777.6 EIW87304.1 - 0.0058 16.4 0.6 0.12 12.2 0.1 2.4 2 0 0 2 2 2 1 RNA binding motif DUF2450 PF10475.4 EIW87304.1 - 0.042 12.7 0.0 0.18 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function N-terminal domain (DUF2450) Ribosomal_L28 PF00830.14 EIW87304.1 - 0.12 12.2 0.1 3.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Ribosomal L28 family RdRP PF05183.7 EIW87305.1 - 4.5e-109 365.7 0.0 6.6e-109 365.2 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase PfkB PF00294.19 EIW87306.1 - 7e-65 219.1 1.5 7.9e-65 218.9 1.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase ABC_tran PF00005.22 EIW87308.1 - 0.027 14.7 0.0 0.062 13.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EIW87308.1 - 0.15 11.5 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynactin PF12455.3 EIW87309.1 - 9.4e-77 257.6 1.0 2.3e-76 256.3 0.0 2.2 2 0 0 2 2 2 1 Dynein associated protein CAP_GLY PF01302.20 EIW87309.1 - 2.5e-22 78.3 1.5 4.3e-22 77.5 0.7 1.7 2 0 0 2 2 2 1 CAP-Gly domain Reo_sigmaC PF04582.7 EIW87309.1 - 0.36 9.9 23.8 0.02 14.0 0.4 4.2 4 1 1 5 5 5 0 Reovirus sigma C capsid protein Raptor_N PF14538.1 EIW87310.1 - 3.4e-62 208.8 0.0 7.5e-62 207.7 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EIW87310.1 - 2.3e-08 33.5 10.5 0.0097 15.7 0.2 6.6 7 0 0 7 7 7 2 WD domain, G-beta repeat HEAT PF02985.17 EIW87310.1 - 2.6e-05 23.8 0.0 0.00026 20.7 0.0 2.7 2 0 0 2 2 2 1 HEAT repeat HEAT_2 PF13646.1 EIW87310.1 - 0.00052 20.2 0.0 0.0021 18.2 0.0 2.1 1 0 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.1 EIW87310.1 - 0.0076 16.7 3.5 0.014 15.8 0.1 3.5 3 0 0 3 3 3 1 HEAT-like repeat Sema PF01403.14 EIW87310.1 - 0.42 9.0 0.1 0.68 8.3 0.0 1.2 1 0 0 1 1 1 0 Sema domain RCC1 PF00415.13 EIW87311.1 - 8.4e-21 73.9 15.9 1.5e-07 31.5 0.1 8.1 7 3 1 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EIW87311.1 - 1.1e-06 28.1 33.3 0.0057 16.2 0.0 8.7 8 2 0 8 8 8 3 Regulator of chromosome condensation (RCC1) repeat Swi5 PF07061.6 EIW87312.1 - 5.6e-18 64.5 3.0 5.9e-18 64.4 2.1 1.0 1 0 0 1 1 1 1 Swi5 Seryl_tRNA_N PF02403.17 EIW87312.1 - 0.0047 16.9 2.6 0.0057 16.6 1.8 1.2 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Macoilin PF09726.4 EIW87312.1 - 0.022 13.0 1.1 0.025 12.8 0.7 1.0 1 0 0 1 1 1 0 Transmembrane protein Occludin_ELL PF07303.8 EIW87312.1 - 0.037 14.7 0.7 0.045 14.4 0.5 1.2 1 0 0 1 1 1 0 Occludin homology domain Sds3 PF08598.6 EIW87312.1 - 0.043 13.3 1.7 0.049 13.1 1.2 1.2 1 0 0 1 1 1 0 Sds3-like Mnd1 PF03962.10 EIW87312.1 - 0.079 12.6 1.8 0.091 12.4 1.2 1.1 1 0 0 1 1 1 0 Mnd1 family HOOK PF05622.7 EIW87312.1 - 0.08 10.7 4.1 0.085 10.6 2.8 1.0 1 0 0 1 1 1 0 HOOK protein DUF1826 PF08856.6 EIW87312.1 - 0.08 12.6 0.1 0.096 12.4 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1826) Fmp27_WPPW PF10359.4 EIW87312.1 - 0.14 10.5 1.5 0.15 10.4 1.0 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DUF2680 PF10925.3 EIW87312.1 - 0.15 11.9 2.1 0.22 11.4 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2680) DUF1192 PF06698.6 EIW87312.1 - 0.21 11.4 1.6 0.29 10.9 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) ABC_tran PF00005.22 EIW87313.1 - 6.5e-49 165.7 0.0 1.7e-23 83.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EIW87313.1 - 7e-20 71.3 55.9 8.6e-11 41.4 23.7 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EIW87313.1 - 1.9e-18 67.4 0.0 5e-07 29.9 0.0 4.2 4 0 0 4 4 4 4 AAA domain AAA_23 PF13476.1 EIW87313.1 - 9e-08 32.6 1.2 0.0071 16.6 0.1 2.3 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EIW87313.1 - 1.7e-05 24.1 0.0 1.1 8.3 0.0 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EIW87313.1 - 1.9e-05 24.0 1.3 0.05 13.1 0.4 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SRP54 PF00448.17 EIW87313.1 - 0.003 17.0 0.4 1.9 7.8 0.0 2.3 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain DUF258 PF03193.11 EIW87313.1 - 0.0036 16.5 0.1 2.9 7.0 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EIW87313.1 - 0.0048 17.0 0.3 2.8 8.0 0.1 3.1 2 2 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EIW87313.1 - 0.015 14.8 2.5 4.7 6.7 0.0 3.5 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 EIW87313.1 - 0.059 12.4 0.2 6.6 5.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.1 EIW87313.1 - 0.41 9.6 0.0 13 4.6 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain HET PF06985.6 EIW87315.1 - 9.4e-25 87.3 0.0 1.5e-24 86.6 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) F-box-like PF12937.2 EIW87316.1 - 5.5e-07 29.2 0.0 9.3e-07 28.4 0.0 1.4 1 1 0 1 1 1 1 F-box-like p450 PF00067.17 EIW87317.1 - 4.7e-65 219.9 0.0 5.8e-65 219.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_A4 PF01828.12 EIW87318.1 - 2.1e-56 190.3 16.2 2.5e-56 190.0 11.2 1.1 1 0 0 1 1 1 1 Peptidase A4 family Peptidase_A4 PF01828.12 EIW87319.1 - 2.5e-55 186.7 11.0 2.7e-55 186.6 7.7 1.0 1 0 0 1 1 1 1 Peptidase A4 family C6 PF01681.12 EIW87319.1 - 3.5 7.7 10.3 0.95 9.5 4.5 2.1 1 1 1 2 2 2 0 C6 domain Peptidase_A4 PF01828.12 EIW87320.1 - 5.2e-63 211.8 11.7 6e-63 211.6 8.1 1.0 1 0 0 1 1 1 1 Peptidase A4 family DUF4466 PF14725.1 EIW87320.1 - 0.019 14.2 1.5 0.024 13.9 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4466) F-box-like PF12937.2 EIW87321.1 - 6.9e-10 38.4 0.8 2e-09 37.0 0.5 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW87321.1 - 0.013 15.1 0.1 0.073 12.7 0.1 2.3 1 0 0 1 1 1 0 F-box domain Ribosomal_L28e PF01778.12 EIW87322.1 - 2.4e-29 102.0 0.0 3.1e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family p450 PF00067.17 EIW87323.1 - 2.4e-48 164.7 0.0 2.9e-48 164.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 pRN1_helical PF13010.1 EIW87323.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Primase helical domain p450 PF00067.17 EIW87324.1 - 3e-52 177.6 0.0 3.4e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CBM_21 PF03370.8 EIW87326.1 - 6.9e-25 87.2 0.0 1.6e-24 86.0 0.0 1.6 1 1 0 1 1 1 1 Putative phosphatase regulatory subunit F-box-like PF12937.2 EIW87328.1 - 9.8e-08 31.6 0.1 2.5e-07 30.2 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EIW87328.1 - 2.1e-06 27.1 0.9 4.2e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 F-box domain PAP_assoc PF03828.14 EIW87329.1 - 2.8e-15 55.9 0.0 5.4e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EIW87329.1 - 8.7e-07 29.1 0.0 1.8e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DNA_pol_B_palm PF14792.1 EIW87329.1 - 0.016 15.2 0.0 0.03 14.3 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase beta palm Ribonuc_2-5A PF06479.7 EIW87329.1 - 0.019 14.8 0.5 0.69 9.7 0.1 2.2 2 0 0 2 2 2 0 Ribonuclease 2-5A Ribosomal_S4 PF00163.14 EIW87330.1 - 3.5e-27 94.6 0.9 7.3e-27 93.5 0.6 1.5 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EIW87330.1 - 1.3e-11 43.6 0.9 1.3e-11 43.6 0.7 2.9 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 EIW87331.1 - 1.4e-37 127.4 3.5 1.4e-37 127.4 2.4 1.6 2 0 0 2 2 2 1 Ribosomal protein L21e LRS4 PF10422.4 EIW87331.1 - 0.017 14.4 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Surface_Ag_2 PF01617.12 EIW87331.1 - 0.066 12.4 0.1 0.08 12.1 0.1 1.2 1 0 0 1 1 1 0 Surface antigen RNA_replicase_B PF03431.8 EIW87331.1 - 0.075 11.2 0.6 0.091 10.9 0.4 1.0 1 0 0 1 1 1 0 RNA replicase, beta-chain F-box-like PF12937.2 EIW87333.1 - 1.4e-05 24.6 2.6 3.9e-05 23.2 1.8 1.8 1 0 0 1 1 1 1 F-box-like Peptidase_A4 PF01828.12 EIW87334.1 - 3.8e-61 205.7 10.5 4.3e-61 205.5 7.3 1.0 1 0 0 1 1 1 1 Peptidase A4 family Peptidase_A4 PF01828.12 EIW87335.1 - 6.7e-53 178.8 9.5 7.3e-53 178.7 6.6 1.0 1 0 0 1 1 1 1 Peptidase A4 family BACON PF13004.2 EIW87335.1 - 0.64 10.2 10.4 0.46 10.7 1.6 2.3 1 1 1 2 2 2 0 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal HET PF06985.6 EIW87336.1 - 1.2e-25 90.3 0.0 2.2e-25 89.4 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_A4 PF01828.12 EIW87337.1 - 6.8e-60 201.6 16.8 7.9e-60 201.4 11.7 1.0 1 0 0 1 1 1 1 Peptidase A4 family Lipase_3 PF01764.20 EIW87338.1 - 5.2e-23 81.2 0.0 7.2e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EIW87338.1 - 0.041 13.6 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW87338.1 - 0.046 13.5 0.1 0.081 12.7 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family HET PF06985.6 EIW87340.1 - 1.1e-27 96.8 0.0 1.6e-27 96.3 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Spc97_Spc98 PF04130.8 EIW87341.1 - 5e-118 394.7 0.0 7.1e-118 394.2 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family HET PF06985.6 EIW87342.1 - 1e-23 84.0 0.0 1.8e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) TP_methylase PF00590.15 EIW87343.1 - 2.6e-37 128.5 3.2 1.2e-36 126.3 1.3 2.3 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EIW87343.1 - 3e-11 43.4 0.0 1.2e-10 41.5 0.0 2.1 1 1 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EIW87343.1 - 0.0003 20.0 0.2 0.00082 18.6 0.0 1.8 2 0 0 2 2 2 1 Sirohaem biosynthesis protein C-terminal SRP14 PF02290.10 EIW87344.1 - 3.2e-20 71.8 1.8 6e-20 70.9 0.0 2.1 2 1 0 2 2 2 1 Signal recognition particle 14kD protein Diphthamide_syn PF01866.12 EIW87344.1 - 0.017 14.3 0.6 0.019 14.2 0.4 1.1 1 0 0 1 1 1 0 Putative diphthamide synthesis protein PIH1 PF08190.7 EIW87344.1 - 0.17 11.2 3.9 0.2 11.0 2.7 1.0 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 Adeno_VII PF03228.9 EIW87344.1 - 0.73 10.4 10.0 1 9.9 6.9 1.3 1 0 0 1 1 1 0 Adenoviral core protein VII AAA_33 PF13671.1 EIW87344.1 - 1.5 8.6 7.0 13 5.6 4.7 2.3 1 1 0 1 1 1 0 AAA domain HET PF06985.6 EIW87345.1 - 4.4e-19 69.0 0.0 7.5e-19 68.2 0.0 1.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 EIW87346.1 - 8.9e-11 41.9 0.0 0.00031 21.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EIW87346.1 - 1.3e-09 37.3 0.0 0.0023 17.9 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EIW87346.1 - 4.4e-09 36.6 0.1 4.4e-06 27.0 0.0 2.5 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EIW87346.1 - 3.6e-08 32.8 0.0 0.00064 19.4 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EIW87346.1 - 1.7e-05 24.8 0.0 0.01 16.0 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Frataxin_Cyay PF01491.11 EIW87346.1 - 0.074 12.8 1.3 0.1 12.4 0.1 1.8 2 0 0 2 2 2 0 Frataxin-like domain DUF3647 PF12363.3 EIW87346.1 - 5.4 7.1 5.5 11 6.1 0.1 2.9 2 1 1 3 3 3 0 Phage protein Pkinase PF00069.20 EIW87347.1 - 8.9e-37 126.6 0.0 5.7e-36 123.9 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW87347.1 - 2.3e-17 62.9 0.0 3.6e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EIW87347.1 - 7.2e-05 22.6 1.7 0.00018 21.3 0.0 2.2 2 1 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EIW87347.1 - 0.00036 19.6 0.0 0.0006 18.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EIW87347.1 - 0.00076 19.1 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.17 EIW87347.1 - 0.0079 15.5 0.1 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Seadorna_VP7 PF07387.6 EIW87347.1 - 0.011 14.5 0.1 0.016 14.0 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.1 EIW87347.1 - 0.015 14.3 0.0 0.028 13.3 0.0 1.4 1 1 0 1 1 1 0 Kinase-like SMC_N PF02463.14 EIW87348.1 - 5.9e-75 251.2 0.0 1e-74 250.5 0.0 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EIW87348.1 - 2.3e-24 85.6 0.0 5.6e-24 84.4 0.0 1.7 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EIW87348.1 - 8.5e-12 45.6 18.0 2.7e-06 27.5 0.0 3.4 3 1 1 4 4 4 2 AAA domain AAA_29 PF13555.1 EIW87348.1 - 1.2e-06 27.9 0.0 2.6e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Reo_sigmaC PF04582.7 EIW87348.1 - 0.023 13.9 16.4 0.18 10.9 0.6 4.0 2 2 2 4 4 4 0 Reovirus sigma C capsid protein AAA_23 PF13476.1 EIW87348.1 - 0.25 11.6 106.2 0.081 13.2 30.5 6.6 2 2 1 3 3 3 0 AAA domain ABC_tran PF00005.22 EIW87348.1 - 0.33 11.2 0.0 0.33 11.2 0.0 4.9 4 2 0 4 4 4 0 ABC transporter Gly_transf_sug PF04488.10 EIW87349.1 - 0.00047 20.5 0.0 0.0012 19.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.7 EIW87349.1 - 0.0014 17.8 0.2 0.0022 17.1 0.1 1.3 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein DUF92 PF01940.11 EIW87350.1 - 0.02 14.0 3.4 0.4 9.7 0.8 2.2 1 1 1 2 2 2 0 Integral membrane protein DUF92 DUF2893 PF11459.3 EIW87350.1 - 0.14 11.9 0.4 4.4 7.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknwon function (DUF2893) Yip1 PF04893.12 EIW87350.1 - 3 7.3 17.1 17 4.8 11.9 1.9 1 1 0 1 1 1 0 Yip1 domain Lipase_3 PF01764.20 EIW87351.1 - 1.1e-20 73.6 0.0 1.5e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EIW87351.1 - 0.001 18.9 0.1 0.002 18.0 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EIW87351.1 - 0.0069 16.1 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EIW87351.1 - 0.022 14.0 0.0 0.029 13.6 0.0 1.1 1 0 0 1 1 1 0 Putative serine esterase (DUF676) HET PF06985.6 EIW87352.1 - 1.6e-23 83.4 0.0 2.5e-23 82.7 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SSPI PF14098.1 EIW87352.1 - 0.026 14.4 0.0 0.054 13.4 0.0 1.5 1 0 0 1 1 1 0 Small, acid-soluble spore protein I HET PF06985.6 EIW87353.1 - 1.2e-25 90.3 0.0 2.1e-25 89.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Herpes_env PF01673.13 EIW87353.1 - 0.36 9.3 0.3 0.52 8.7 0.2 1.1 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein DUF3279 PF11682.3 EIW87354.1 - 0.0045 16.5 0.3 0.0068 15.9 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3279) TINF2_N PF14973.1 EIW87354.1 - 0.0065 16.6 0.1 0.0097 16.0 0.1 1.2 1 0 0 1 1 1 1 TERF1-interacting nuclear factor 2 N-terminus DUF726 PF05277.7 EIW87355.1 - 1.4e-114 382.6 0.7 2.2e-114 381.9 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_5 PF12695.2 EIW87355.1 - 0.0023 17.7 0.1 0.0059 16.3 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EIW87355.1 - 0.025 14.1 0.0 0.048 13.2 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EIW87355.1 - 0.24 10.8 0.0 0.43 9.9 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase RRM_1 PF00076.17 EIW87357.1 - 7.4e-17 60.7 0.0 9.1e-17 60.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EIW87357.1 - 8.7e-16 57.6 0.0 1.1e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EIW87357.1 - 5e-10 39.0 0.0 7.2e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EIW87357.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain HET PF06985.6 EIW87358.1 - 1.3e-22 80.4 0.0 2.2e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) tRNA-synt_His PF13393.1 EIW87359.1 - 1e-39 136.4 0.2 1.8e-35 122.5 0.0 2.8 3 0 0 3 3 3 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EIW87359.1 - 1.3e-18 67.1 0.0 2.7e-18 66.1 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EIW87359.1 - 2.7e-09 36.8 0.0 5.1e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain DUF4305 PF14146.1 EIW87359.1 - 0.17 11.6 0.1 0.38 10.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4305) tRNA-synt_2 PF00152.15 EIW87359.1 - 0.18 10.5 0.0 2 7.0 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II (D, K and N) CDP-OH_P_transf PF01066.16 EIW87360.1 - 8.5e-17 61.3 1.2 8.5e-17 61.3 0.8 2.3 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase HET PF06985.6 EIW87361.1 - 3.3e-25 88.8 0.0 6.8e-25 87.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 EIW87362.1 - 1.1e-20 74.2 0.0 1.7e-20 73.5 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SCP1201-deam PF14428.1 EIW87363.1 - 0.11 12.1 1.0 0.22 11.2 0.1 1.9 2 0 0 2 2 2 0 SCP1.201-like deaminase Nop14 PF04147.7 EIW87364.1 - 0.12 10.2 16.1 0.14 10.0 11.2 1.1 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.8 EIW87364.1 - 1.1 9.0 19.9 1.7 8.4 13.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Herpes_LMP1 PF05297.6 EIW87364.1 - 4 6.2 22.5 5.4 5.8 15.6 1.3 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Sporozoite_P67 PF05642.6 EIW87364.1 - 6.6 4.4 8.8 11 3.7 6.1 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF16 PF01519.11 EIW87366.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function DUF16 Baculo_PEP_C PF04513.7 EIW87366.1 - 0.32 10.8 1.4 0.7 9.7 0.9 1.5 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Nop14 PF04147.7 EIW87368.1 - 0.31 8.9 8.9 0.44 8.4 6.2 1.2 1 0 0 1 1 1 0 Nop14-like family Nucleoplasmin PF03066.10 EIW87368.1 - 7.8 6.0 11.0 15 5.0 7.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin Tet_JBP PF12851.2 EIW87369.1 - 1.4e-07 30.9 0.0 2e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily zf-B_box PF00643.19 EIW87370.1 - 0.12 12.2 3.5 0.54 10.1 2.4 2.2 1 0 0 1 1 1 0 B-box zinc finger Cyclin_N PF00134.18 EIW87372.1 - 0.0036 16.8 2.2 0.29 10.7 0.3 2.1 1 1 1 2 2 2 2 Cyclin, N-terminal domain OmpH PF03938.9 EIW87373.1 - 0.025 14.5 0.3 0.35 10.7 0.0 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Sigma54_CBD PF04963.8 EIW87374.1 - 0.085 12.2 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain Glyco_hydro_76 PF03663.9 EIW87376.1 - 0.0045 16.4 0.3 0.0066 15.8 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Tet_JBP PF12851.2 EIW87378.1 - 3.2e-15 55.8 0.0 4e-15 55.5 0.0 1.0 1 0 0 1 1 1 1 Oxygenase domain of the 2OGFeDO superfamily rve PF00665.21 EIW87382.1 - 2.6e-08 33.9 0.0 2.7e-08 33.9 0.0 1.0 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EIW87382.1 - 0.0016 17.9 0.0 0.0028 17.1 0.0 1.5 2 0 0 2 2 2 1 Integrase core domain Peptidase_C48 PF02902.14 EIW87383.1 - 6.3e-06 25.9 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain GRP PF07172.6 EIW87383.1 - 0.01 16.2 18.0 0.021 15.3 12.5 1.5 1 0 0 1 1 1 0 Glycine rich protein family HET PF06985.6 EIW87384.1 - 1.7e-17 63.8 0.0 3.2e-17 63.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aldo_ket_red PF00248.16 EIW87386.1 - 2e-63 213.8 0.0 2.3e-63 213.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.16 EIW87387.1 - 1.8e-66 223.8 0.0 2.2e-66 223.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family TMEM61 PF15105.1 EIW87388.1 - 0.029 13.8 0.1 7.5 6.0 0.0 2.4 2 0 0 2 2 2 0 TMEM61 protein family DUF4131 PF13567.1 EIW87388.1 - 0.33 10.3 2.8 0.88 8.9 1.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3592 PF12158.3 EIW87388.1 - 2.4 7.9 5.6 58 3.4 4.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3592) DUF3684 PF12449.3 EIW87389.1 - 8.3e-215 715.7 0.0 1.3e-132 443.6 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 EIW87389.1 - 0.0059 16.2 0.0 0.021 14.4 0.0 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EIW87389.1 - 0.0061 16.2 0.1 0.024 14.3 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CSTF2_hinge PF14327.1 EIW87390.1 - 5.7e-10 39.1 2.1 5.7e-10 39.1 1.5 2.5 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.1 EIW87390.1 - 2.2e-05 23.6 2.6 7.3e-05 21.9 1.8 2.0 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal DUF605 PF04652.11 EIW87390.1 - 1.5 8.1 25.5 1.7 7.9 17.7 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EIW87390.1 - 8.4 4.4 32.2 9.7 4.2 22.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Fasciclin PF02469.17 EIW87391.1 - 1.1e-11 44.7 0.1 3.1e-11 43.3 0.0 1.7 2 1 0 2 2 2 1 Fasciclin domain Aldo_ket_red PF00248.16 EIW87392.1 - 6.4e-63 212.2 0.0 7.6e-63 211.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family YhhN PF07947.9 EIW87393.1 - 0.079 12.3 1.4 0.11 11.8 1.0 1.1 1 0 0 1 1 1 0 YhhN-like protein DUF4229 PF14012.1 EIW87393.1 - 3.5 7.5 6.7 1.1 9.2 1.9 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4229) Adap_comp_sub PF00928.16 EIW87395.1 - 1.1e-20 73.8 0.0 1.5e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EIW87395.1 - 1.9e-06 27.6 0.0 2.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Phytoreo_Pns PF05451.6 EIW87395.1 - 0.07 11.7 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns10/11 Med3 PF11593.3 EIW87396.1 - 0.0013 18.0 13.6 0.0022 17.3 9.5 1.3 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal ubiquitin PF00240.18 EIW87397.1 - 1.7e-35 120.2 0.7 1.9e-35 120.0 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EIW87397.1 - 1.4e-18 66.3 0.3 1.6e-18 66.1 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EIW87397.1 - 2.7e-06 27.5 0.1 1.1e-05 25.5 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EIW87397.1 - 0.0016 18.1 0.0 0.0018 17.9 0.0 1.0 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EIW87397.1 - 0.0033 17.2 0.1 0.0071 16.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EIW87397.1 - 0.011 15.8 0.1 0.013 15.6 0.1 1.2 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EIW87397.1 - 0.065 13.2 0.0 0.17 11.9 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) Tash_PEST PF07708.6 EIW87397.1 - 0.33 10.9 1.8 0.64 10.0 1.2 1.4 1 0 0 1 1 1 0 Tash protein PEST motif Glutaredoxin PF00462.19 EIW87398.1 - 3.2e-09 36.6 0.0 5.9e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_2 PF13098.1 EIW87398.1 - 0.0011 19.1 0.1 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_4 PF13462.1 EIW87398.1 - 0.0027 17.7 0.1 1.1 9.2 0.1 2.5 1 1 2 3 3 3 2 Thioredoxin GST_N_3 PF13417.1 EIW87398.1 - 0.066 13.4 0.0 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain SH3BGR PF04908.10 EIW87398.1 - 0.072 13.0 0.1 0.24 11.3 0.0 1.7 2 0 0 2 2 2 0 SH3-binding, glutamic acid-rich protein NIF3 PF01784.13 EIW87399.1 - 1.9e-64 217.5 0.0 2.3e-64 217.2 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) ETF PF01012.16 EIW87399.1 - 0.0048 16.6 0.2 0.014 15.1 0.0 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein domain SERTA PF06031.8 EIW87405.1 - 0.011 14.9 0.3 0.025 13.8 0.2 1.6 1 0 0 1 1 1 0 SERTA motif Peptidase_M76 PF09768.4 EIW87409.1 - 8.1e-66 220.7 0.1 9.7e-66 220.4 0.1 1.1 1 0 0 1 1 1 1 Peptidase M76 family GPI-anchored PF10342.4 EIW87410.1 - 2.6e-11 43.8 5.5 4.8e-11 42.9 3.8 1.4 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family CIMR PF00878.13 EIW87411.1 - 5.5e-15 55.4 0.0 2.6e-07 30.5 0.0 2.2 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.10 EIW87411.1 - 3e-05 23.1 0.0 4.4e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Mannose-6-phosphate receptor ATG27 PF09451.5 EIW87411.1 - 0.0038 16.4 1.0 0.025 13.8 0.4 2.2 2 1 0 2 2 2 1 Autophagy-related protein 27 Complex1_49kDa PF00346.14 EIW87412.1 - 1.4e-115 385.0 0.0 1.9e-115 384.5 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit NiFeSe_Hases PF00374.14 EIW87412.1 - 0.034 12.9 0.0 0.051 12.3 0.0 1.2 1 0 0 1 1 1 0 Nickel-dependent hydrogenase Amidohydro_5 PF13594.1 EIW87413.1 - 1.4e-08 34.4 0.0 3.2e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EIW87413.1 - 1.5e-06 28.4 4.0 2.8e-06 27.5 1.1 2.3 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 EIW87413.1 - 4e-06 26.7 2.9 5.1e-06 26.3 0.3 2.5 3 1 0 3 3 3 1 Amidohydrolase family Amidohydro_3 PF07969.6 EIW87413.1 - 0.0047 16.1 0.1 0.43 9.7 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.15 EIW87414.1 - 1e-12 48.4 0.3 1.6e-11 44.4 0.0 2.6 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 EIW87414.1 - 1.7e-08 34.8 10.7 8e-08 32.6 5.4 2.9 1 1 1 2 2 2 1 Amidohydrolase Amidohydro_5 PF13594.1 EIW87414.1 - 1.7e-08 34.1 0.0 5.2e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EIW87414.1 - 0.041 13.1 9.1 0.067 12.3 0.4 2.8 2 1 0 3 3 3 0 Amidohydrolase family PUF PF00806.14 EIW87416.1 - 2.2e-30 102.4 0.3 3.2e-07 29.4 0.0 5.9 6 0 0 6 6 6 5 Pumilio-family RNA binding repeat Heme_oxygenase PF01126.15 EIW87417.1 - 0.025 14.1 0.2 0.036 13.6 0.1 1.3 1 0 0 1 1 1 0 Heme oxygenase XLF PF09302.6 EIW87417.1 - 0.026 14.2 3.2 2.2 8.0 0.0 2.9 3 0 0 3 3 3 0 XLF (XRCC4-like factor) ATG16 PF08614.6 EIW87417.1 - 0.065 13.0 15.8 0.024 14.4 6.7 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) APG6 PF04111.7 EIW87417.1 - 0.1 11.6 11.7 0.053 12.5 4.0 2.2 2 0 0 2 2 2 0 Autophagy protein Apg6 CALCOCO1 PF07888.6 EIW87417.1 - 0.16 10.1 10.1 0.031 12.5 4.0 1.6 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.4 EIW87417.1 - 1.1 9.1 25.4 0.26 11.1 2.7 3.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CDC37_N PF03234.9 EIW87417.1 - 1.9 8.7 8.1 1.4 9.1 3.3 2.2 1 1 1 2 2 2 0 Cdc37 N terminal kinase binding DUF4200 PF13863.1 EIW87417.1 - 3.3 7.6 17.1 1.6 8.6 1.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) DivIVA PF05103.8 EIW87417.1 - 7.4 6.6 15.3 4.4 7.3 1.2 3.1 3 0 0 3 3 3 0 DivIVA protein Utp14 PF04615.8 EIW87419.1 - 3.4e-159 531.3 39.6 3.4e-159 531.3 27.5 2.3 1 1 1 2 2 2 1 Utp14 protein Peptidase_S10 PF00450.17 EIW87420.1 - 2.5e-115 386.0 0.0 3.1e-115 385.6 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EIW87420.1 - 0.0053 16.6 0.2 0.19 11.5 0.1 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Pkinase PF00069.20 EIW87421.1 - 2.2e-73 246.5 0.0 3.1e-73 246.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW87421.1 - 7.9e-39 133.2 0.0 1.1e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EIW87421.1 - 2.5e-05 23.3 0.0 3.8e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EIW87421.1 - 0.00022 20.6 0.0 0.0004 19.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family UBA_2 PF08587.6 EIW87421.1 - 0.0045 17.1 0.2 0.011 15.8 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kdo PF06293.9 EIW87421.1 - 0.01 14.9 0.1 0.052 12.6 0.1 1.9 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EIW87421.1 - 0.058 13.1 4.9 0.23 11.1 0.3 2.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family Peptidase_M17 PF00883.16 EIW87422.1 - 2.1e-121 404.5 0.0 2.6e-121 404.3 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 EIW87422.1 - 9.5e-07 28.6 0.1 1.8e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Peptidase_M17 PF00883.16 EIW87423.1 - 8.3e-12 44.5 0.0 1e-11 44.3 0.0 1.0 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain EthD PF07110.6 EIW87424.1 - 1.3e-06 29.2 0.6 1.5e-06 29.0 0.4 1.1 1 0 0 1 1 1 1 EthD domain Transposase_21 PF02992.9 EIW87427.1 - 4.7e-07 29.1 0.1 8.5e-07 28.2 0.0 1.4 1 0 0 1 1 1 1 Transposase family tnp2 DUF1115 PF06544.7 EIW87429.1 - 9.7e-11 41.4 0.0 2.2e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DUF3841 PF12952.2 EIW87429.1 - 0.13 11.7 0.1 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3841) Pkinase PF00069.20 EIW87431.1 - 2.3e-09 36.7 0.0 8.2e-09 34.9 0.0 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW87431.1 - 0.0032 16.5 0.0 0.0053 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Histone PF00125.19 EIW87432.1 - 4.1e-30 103.7 0.8 6.7e-30 103.0 0.6 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EIW87432.1 - 1.4e-05 25.2 0.1 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EIW87432.1 - 0.0012 18.8 1.9 0.0014 18.6 0.1 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EIW87432.1 - 0.015 15.0 0.1 0.026 14.2 0.1 1.4 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EIW87432.1 - 0.19 10.9 1.9 0.21 10.7 1.4 1.2 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T Glyco_hydro_28 PF00295.12 EIW87433.1 - 6.6e-38 130.4 0.7 6.6e-38 130.4 0.5 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 28 Glyco_hydro_28 PF00295.12 EIW87434.1 - 2.8e-38 131.7 0.3 7.1e-38 130.3 0.2 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 DUF2235 PF09994.4 EIW87435.1 - 2.2e-77 260.1 0.1 3.6e-77 259.4 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF3850 PF12961.2 EIW87435.1 - 0.0051 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Domain of Unknown Function with PDB structure (DUF3850) Abhydrolase_5 PF12695.2 EIW87435.1 - 0.01 15.6 0.0 0.047 13.4 0.0 1.7 2 1 0 2 2 2 0 Alpha/beta hydrolase family DUF2235 PF09994.4 EIW87436.1 - 3.8e-78 262.6 0.6 5.3e-78 262.1 0.4 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EIW87436.1 - 0.009 15.7 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EIW87436.1 - 0.035 13.8 0.0 0.43 10.2 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Na_Ca_ex PF01699.19 EIW87437.1 - 1.7e-41 141.0 34.1 8.3e-26 90.2 8.1 3.3 2 1 1 3 3 3 2 Sodium/calcium exchanger protein DUF3742 PF12553.3 EIW87437.1 - 0.3 11.5 0.0 0.3 11.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3742) Fungal_trans PF04082.13 EIW87438.1 - 1e-14 54.0 0.7 1.6e-14 53.4 0.5 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DIOX_N PF14226.1 EIW87439.1 - 4.8e-17 62.5 0.0 8.6e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EIW87439.1 - 2.2e-13 50.3 0.0 3.7e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GH3 PF03321.8 EIW87440.1 - 1.5e-50 172.2 0.0 1.9e-50 171.9 0.0 1.0 1 0 0 1 1 1 1 GH3 auxin-responsive promoter EthD PF07110.6 EIW87441.1 - 0.0046 17.8 0.0 0.0072 17.2 0.0 1.3 1 0 0 1 1 1 1 EthD domain PepSY_2 PF13670.1 EIW87442.1 - 0.004 17.0 0.4 0.011 15.6 0.2 1.6 1 1 1 2 2 2 1 Peptidase propeptide and YPEB domain DUF3328 PF11807.3 EIW87443.1 - 7.1e-25 87.9 0.8 1.4e-24 87.0 0.6 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Peptidase_S9 PF00326.16 EIW87444.1 - 9.6e-42 142.6 0.1 1.9e-41 141.6 0.0 1.5 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EIW87444.1 - 4.9e-12 45.8 0.1 9e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EIW87444.1 - 5.5e-08 32.9 0.0 3.3e-07 30.4 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EIW87444.1 - 6.9e-05 22.3 0.8 0.0046 16.4 0.0 2.2 1 1 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 EIW87444.1 - 0.00026 20.3 0.0 0.00049 19.4 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.15 EIW87444.1 - 0.0068 15.8 0.0 0.016 14.6 0.0 1.8 1 0 0 1 1 1 1 Putative esterase LIP PF03583.9 EIW87444.1 - 0.0092 15.2 1.1 0.051 12.7 0.0 2.1 2 0 0 2 2 2 1 Secretory lipase Abhydrolase_4 PF08386.5 EIW87444.1 - 0.011 15.6 0.0 0.028 14.2 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein AXE1 PF05448.7 EIW87444.1 - 0.014 13.8 0.2 0.09 11.2 0.1 2.2 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Esterase_phd PF10503.4 EIW87444.1 - 0.015 14.5 0.1 0.083 12.1 0.0 2.0 1 1 0 1 1 1 0 Esterase PHB depolymerase Abhydrolase_3 PF07859.8 EIW87444.1 - 0.021 14.4 0.1 0.13 11.8 0.0 2.2 2 1 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EIW87444.1 - 0.027 14.0 0.0 0.14 11.6 0.0 2.0 1 1 0 2 2 2 0 alpha/beta hydrolase fold FSH1 PF03959.8 EIW87444.1 - 0.096 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PAE PF03283.8 EIW87444.1 - 0.096 11.2 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Pectinacetylesterase BAAT_C PF08840.6 EIW87444.1 - 0.14 11.8 0.0 0.41 10.3 0.0 1.7 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal ABC2_membrane_5 PF13346.1 EIW87447.1 - 0.0089 15.3 8.5 0.0089 15.3 5.9 2.4 2 1 1 3 3 3 1 ABC-2 family transporter protein SNF2_N PF00176.18 EIW87448.1 - 2.7e-76 256.2 0.0 5.2e-76 255.2 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EIW87448.1 - 1.6e-40 137.4 0.4 1.6e-40 137.4 0.3 2.6 3 0 0 3 3 3 1 SLIDE HAND PF09110.6 EIW87448.1 - 4e-29 101.2 3.8 4e-29 101.2 2.6 3.6 4 0 0 4 4 4 1 HAND Helicase_C PF00271.26 EIW87448.1 - 6.2e-15 54.8 0.0 2.4e-14 52.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EIW87448.1 - 5.7e-07 29.5 1.4 2.8e-05 24.0 0.0 3.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EIW87448.1 - 3.9e-05 23.2 0.0 0.0001 21.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_14 PF13173.1 EIW87448.1 - 0.00042 20.2 0.2 0.019 14.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain DBINO PF13892.1 EIW87448.1 - 0.0061 16.5 4.4 0.0061 16.5 3.0 4.6 5 0 0 5 5 5 1 DNA-binding domain DEAD_2 PF06733.10 EIW87448.1 - 0.013 14.9 0.1 0.033 13.6 0.1 1.6 1 0 0 1 1 1 0 DEAD_2 EI24 PF07264.6 EIW87449.1 - 0.0021 17.5 5.4 0.0053 16.2 3.8 1.9 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) AhpC-TSA_2 PF13911.1 EIW87450.1 - 3.5e-17 62.3 0.0 4.9e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EIW87450.1 - 2.3e-05 24.0 0.0 3.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EIW87450.1 - 0.0012 18.4 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin DUF3328 PF11807.3 EIW87451.1 - 2.5e-20 73.1 0.2 2.6e-20 73.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Cohesin_load PF10345.4 EIW87452.1 - 1.3e-05 23.6 0.6 0.012 13.8 0.1 2.9 2 1 0 2 2 2 2 Cohesin loading factor TPR_14 PF13428.1 EIW87452.1 - 0.028 15.0 0.1 23 5.9 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EIW87452.1 - 0.029 14.1 0.0 0.15 11.9 0.0 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 EIW87452.1 - 0.031 14.1 0.0 0.26 11.2 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3210 PF11489.3 EIW87452.1 - 0.087 11.5 0.2 0.15 10.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3210) TPR_12 PF13424.1 EIW87452.1 - 1 9.3 8.8 1.9 8.4 0.5 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Metalloenzyme PF01676.13 EIW87453.1 - 9e-79 264.4 0.6 1e-78 264.2 0.4 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 EIW87453.1 - 1.1e-67 227.6 0.2 2.2e-67 226.6 0.1 1.5 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Sulfatase PF00884.18 EIW87453.1 - 1.7e-05 24.2 0.5 0.00077 18.7 0.1 2.8 2 1 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 EIW87453.1 - 0.00037 19.9 0.1 0.00054 19.3 0.0 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase VWA_2 PF13519.1 EIW87453.1 - 0.039 14.0 0.1 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 von Willebrand factor type A domain Tetraspannin PF00335.15 EIW87456.1 - 3.6e-11 42.7 14.0 4.9e-11 42.3 9.7 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF3278 PF11683.3 EIW87456.1 - 0.014 15.4 0.2 0.038 13.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) IspA PF04279.10 EIW87456.1 - 0.28 11.1 3.8 0.17 11.8 1.2 1.7 2 0 0 2 2 2 0 Intracellular septation protein A FTR1 PF03239.9 EIW87456.1 - 0.41 9.5 4.3 0.062 12.2 0.3 1.5 2 0 0 2 2 2 0 Iron permease FTR1 family APH PF01636.18 EIW87457.1 - 5.2e-12 46.0 0.6 1.5e-11 44.5 0.0 2.0 2 1 0 2 2 2 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EIW87457.1 - 8.5e-07 27.9 0.0 0.0066 15.1 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1679) ubiquitin PF00240.18 EIW87458.1 - 9.7e-19 66.5 0.4 1.5e-18 65.9 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EIW87458.1 - 8.1e-11 41.4 0.0 1.8e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain Rad60-SLD PF11976.3 EIW87458.1 - 1.1e-09 37.7 0.4 1.9e-09 37.0 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EIW87458.1 - 1.1e-06 28.7 0.0 1.9e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain XPC-binding PF09280.6 EIW87458.1 - 0.0068 15.8 6.8 0.0068 15.8 4.7 3.0 2 1 1 3 3 3 1 XPC-binding domain Rad60-SLD_2 PF13881.1 EIW87458.1 - 0.042 13.7 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Adaptin_N PF01602.15 EIW87463.1 - 6e-92 308.6 7.3 8.8e-92 308.0 5.1 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EIW87463.1 - 4.2e-66 220.5 0.0 1.1e-65 219.2 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EIW87463.1 - 2.4e-57 192.5 0.0 6.5e-57 191.1 0.0 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EIW87463.1 - 1.7e-13 50.6 0.1 0.0018 18.4 0.0 5.8 1 1 2 4 4 4 3 HEAT repeats HEAT PF02985.17 EIW87463.1 - 1.6e-07 30.7 0.6 0.054 13.5 0.0 5.5 4 1 1 5 5 5 2 HEAT repeat Cnd1 PF12717.2 EIW87463.1 - 4.3e-05 23.4 8.3 0.15 11.8 2.4 4.6 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Arm_2 PF04826.8 EIW87463.1 - 0.00039 19.6 1.0 0.15 11.1 0.0 3.2 2 1 1 3 3 3 2 Armadillo-like HEAT_EZ PF13513.1 EIW87463.1 - 0.003 18.0 0.1 14 6.3 0.0 5.5 5 2 2 7 7 7 0 HEAT-like repeat ParcG PF10274.4 EIW87463.1 - 0.019 14.9 1.1 1.4 8.7 0.0 2.7 2 0 0 2 2 2 0 Parkin co-regulated protein KRAP_IP3R_bind PF14722.1 EIW87463.1 - 0.038 13.5 0.2 0.087 12.3 0.1 1.6 1 0 0 1 1 1 0 Ki-ras-induced actin-interacting protein-IP3R-interacting domain DUF2435 PF10363.4 EIW87463.1 - 0.059 13.2 4.2 0.91 9.4 0.0 4.2 4 1 0 4 4 4 0 Protein of unknown function (DUF2435) ATP-synt_J PF04911.7 EIW87464.1 - 4e-22 77.4 0.2 4.3e-22 77.3 0.2 1.0 1 0 0 1 1 1 1 ATP synthase j chain Transp_cyt_pur PF02133.10 EIW87465.1 - 2.2e-27 95.7 33.0 3.8e-27 94.9 22.9 1.3 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Cellulase PF00150.13 EIW87466.1 - 1.6e-44 152.2 0.0 1.9e-44 151.9 0.0 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.1 EIW87466.1 - 0.022 14.0 0.1 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) Lipase_GDSL_2 PF13472.1 EIW87468.1 - 1.9e-06 28.1 0.0 2.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EIW87468.1 - 2.7e-05 24.1 0.0 0.00026 20.8 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Alginate_lyase PF05426.7 EIW87469.1 - 2.9e-45 154.7 0.0 4.4e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Alginate lyase Pkinase PF00069.20 EIW87470.1 - 2.6e-41 141.4 0.0 3.2e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EIW87470.1 - 2.6e-34 118.4 0.0 3.1e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EIW87470.1 - 0.14 11.1 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cas1_AcylT PF07779.7 EIW87471.1 - 1.9e-159 531.2 19.2 6.5e-158 526.2 13.3 2.0 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 EIW87471.1 - 3.3e-29 102.5 0.0 4.8e-29 101.9 0.0 1.3 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p AMP-binding PF00501.23 EIW87472.1 - 1.7e-96 323.1 0.0 2.7e-96 322.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EIW87472.1 - 1.1e-66 224.9 0.0 2.2e-66 223.9 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Condensation PF00668.15 EIW87472.1 - 2e-49 168.0 0.1 3.3e-49 167.3 0.0 1.3 1 0 0 1 1 1 1 Condensation domain Acyl_transf_1 PF00698.16 EIW87472.1 - 3.4e-38 131.7 0.0 6.5e-38 130.8 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EIW87472.1 - 1.2e-34 119.5 0.0 3.6e-34 118.0 0.0 1.7 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.17 EIW87472.1 - 2.3e-31 108.1 0.3 2.3e-31 108.1 0.2 2.6 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EIW87472.1 - 8.8e-31 107.0 0.1 3.1e-30 105.2 0.1 2.0 1 0 0 1 1 1 1 short chain dehydrogenase PS-DH PF14765.1 EIW87472.1 - 3.1e-21 75.7 0.0 9.2e-21 74.2 0.0 1.7 2 0 0 2 2 2 1 Polyketide synthase dehydratase Thioesterase PF00975.15 EIW87472.1 - 1.3e-16 61.4 0.0 2.4e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain PP-binding PF00550.20 EIW87472.1 - 3.3e-15 56.0 0.7 3.3e-09 36.8 0.0 3.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EIW87472.1 - 1.6e-09 38.5 0.0 5.4e-09 36.8 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Abhydrolase_6 PF12697.2 EIW87472.1 - 1.6e-06 28.1 0.9 1.1e-05 25.4 0.0 2.6 2 1 1 3 3 3 1 Alpha/beta hydrolase family Thiolase_N PF00108.18 EIW87472.1 - 0.0013 17.7 0.1 0.0026 16.7 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EIW87472.1 - 0.0028 17.2 2.4 0.0045 16.6 0.1 2.6 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Abhydrolase_5 PF12695.2 EIW87472.1 - 0.036 13.8 0.0 0.21 11.3 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family RRM_1 PF00076.17 EIW87472.1 - 0.25 11.0 0.1 3.5 7.3 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)