# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Fungal_trans PF04082.13 EXF72904.1 - 2e-34 118.6 0.0 7.6e-34 116.7 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF72904.1 - 8.4e-11 41.6 13.6 1.6e-10 40.7 9.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fer2 PF00111.22 EXF72904.1 - 0.049 13.3 2.3 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain Peptidase_C65 PF10275.4 EXF72905.1 - 1.4e-64 217.7 0.0 2.7e-64 216.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase C65 Otubain PCI PF01399.22 EXF72907.1 - 1.8e-19 69.9 0.3 5.2e-19 68.5 0.0 2.0 2 0 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EXF72907.1 - 3.9e-05 23.4 0.2 0.00012 21.8 0.1 1.8 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 FeoC PF09012.5 EXF72907.1 - 0.0032 17.1 0.1 0.019 14.6 0.0 2.3 2 0 0 2 2 2 1 FeoC like transcriptional regulator DUF4423 PF14394.1 EXF72907.1 - 0.015 14.8 0.2 0.089 12.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) TPR_10 PF13374.1 EXF72907.1 - 0.049 13.5 0.2 5 7.1 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EXF72907.1 - 0.076 12.8 0.8 26 4.9 0.1 4.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EXF72907.1 - 0.099 12.6 4.1 0.83 9.7 0.2 4.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Ipi1_N PF12333.3 EXF72907.1 - 0.1 12.5 0.2 0.46 10.4 0.0 2.1 2 0 0 2 2 2 0 Rix1 complex component involved in 60S ribosome maturation TPR_12 PF13424.1 EXF72907.1 - 0.19 11.6 4.6 1.4 8.9 0.1 3.6 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EXF72907.1 - 0.22 11.3 1.6 0.54 10.1 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat CWC25 PF12542.3 EXF72908.1 - 1.5e-24 86.2 0.4 1.5e-24 86.2 0.3 4.0 4 1 0 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EXF72908.1 - 6.3e-13 48.5 7.3 6.3e-13 48.5 5.1 3.2 2 1 1 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR Ras PF00071.17 EXF72909.1 - 1.5e-54 183.7 0.0 1.8e-54 183.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EXF72909.1 - 7e-16 58.7 0.0 9.7e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EXF72909.1 - 1e-09 37.8 0.0 1.5e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EXF72909.1 - 0.00019 20.6 0.0 0.00024 20.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EXF72909.1 - 0.0055 15.4 0.0 0.0063 15.2 0.0 1.3 1 1 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.5 EXF72909.1 - 0.0068 15.6 0.0 0.0091 15.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EXF72909.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EXF72909.1 - 0.08 13.2 0.0 0.11 12.8 0.0 1.5 1 1 0 1 1 1 0 ABC transporter Nucleoporin_FG PF13634.1 EXF72910.1 - 0.0047 17.1 4.3 0.0086 16.3 3.0 1.4 1 0 0 1 1 1 1 Nucleoporin FG repeat region DUF1275 PF06912.6 EXF72911.1 - 5.4e-43 146.6 4.7 6.7e-43 146.3 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) MFS_1 PF07690.11 EXF72911.1 - 0.0016 17.2 9.3 0.013 14.2 1.5 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.1 EXF72911.1 - 0.52 9.6 11.4 2.3 7.5 0.2 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) Glyco_hydro_16 PF00722.16 EXF72912.1 - 3.2e-37 127.5 2.5 5.7e-37 126.7 1.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Fungal_trans_2 PF11951.3 EXF72914.1 - 4.4e-42 144.0 0.1 6.7e-42 143.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF72914.1 - 6.9e-07 29.0 6.5 1.2e-06 28.2 4.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HisKA_3 PF07730.8 EXF72914.1 - 0.01 16.1 3.7 13 6.1 0.0 3.7 3 0 0 3 3 3 0 Histidine kinase ADH_N PF08240.7 EXF72915.1 - 5.2e-27 93.7 3.6 1.3e-26 92.4 2.5 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF72915.1 - 5.3e-12 45.4 0.2 8.9e-12 44.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 EXF72915.1 - 0.0071 16.4 0.1 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase KdgT PF03812.8 EXF72915.1 - 0.024 13.8 0.3 0.042 13.0 0.2 1.3 1 0 0 1 1 1 0 2-keto-3-deoxygluconate permease TrkA_N PF02254.13 EXF72915.1 - 0.081 12.9 0.1 0.2 11.6 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 EXF72915.1 - 0.09 12.1 0.0 0.2 11.0 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short_C2 PF13561.1 EXF72916.1 - 2.3e-37 129.0 0.0 2.7e-37 128.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EXF72916.1 - 2.7e-35 121.7 1.0 3.4e-35 121.4 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF72916.1 - 8.1e-18 64.7 0.2 1.1e-17 64.3 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF72916.1 - 3.9e-06 26.4 0.3 1.7e-05 24.4 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF4246 PF14033.1 EXF72917.1 - 4.5e-148 494.0 0.0 7.3e-148 493.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) 2OG-FeII_Oxy_5 PF13759.1 EXF72917.1 - 0.024 14.8 0.0 0.055 13.7 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Sugar_tr PF00083.19 EXF72918.1 - 4.4e-86 289.2 20.7 5.4e-86 288.9 14.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF72918.1 - 4.4e-16 58.5 42.5 2.2e-08 33.2 14.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily UAA PF08449.6 EXF72918.1 - 0.025 13.5 2.0 0.026 13.4 0.2 1.8 2 0 0 2 2 2 0 UAA transporter family Aminotran_1_2 PF00155.16 EXF72919.1 - 2.9e-35 121.8 0.0 3.5e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EXF72919.1 - 1.7e-06 27.0 0.0 3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_MocR PF12897.2 EXF72919.1 - 2.8e-05 22.8 0.0 3.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Cys_Met_Meta_PP PF01053.15 EXF72919.1 - 0.00026 19.4 0.0 0.00038 18.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EXF72919.1 - 0.00047 19.4 0.0 0.0007 18.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Alliinase_C PF04864.8 EXF72919.1 - 0.1 11.2 0.1 0.22 10.1 0.1 1.6 1 1 0 1 1 1 0 Allinase CPSase_L_D2 PF02786.12 EXF72920.1 - 4.4e-71 238.5 0.0 6.7e-71 237.9 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.14 EXF72920.1 - 1.1e-36 125.0 0.0 4.5e-36 123.0 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain CPSase_L_chain PF00289.17 EXF72920.1 - 3e-35 120.6 0.0 6e-35 119.6 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_lipoyl PF00364.17 EXF72920.1 - 7.8e-17 60.6 1.9 3.3e-16 58.6 1.2 2.3 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EXF72920.1 - 1.9e-16 60.3 0.0 3.8e-16 59.3 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EXF72920.1 - 3.9e-15 55.4 0.0 6.5e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 EXF72920.1 - 1.6e-09 37.2 0.1 0.00032 20.3 0.0 3.0 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EXF72920.1 - 1.1e-07 31.3 0.0 2.9e-07 30.0 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus HlyD_3 PF13437.1 EXF72920.1 - 9.6e-06 25.8 0.1 0.16 12.3 0.0 3.1 2 0 0 2 2 2 2 HlyD family secretion protein HlyD PF00529.15 EXF72920.1 - 1.5e-05 24.4 0.1 0.021 14.1 0.0 2.4 1 1 1 2 2 2 2 HlyD family secretion protein ATP-grasp PF02222.17 EXF72920.1 - 2.6e-05 23.6 0.0 6.1e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EXF72920.1 - 0.0039 17.0 0.0 0.0096 15.8 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EXF72920.1 - 0.0057 16.1 0.0 0.048 13.1 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_2 PF12700.2 EXF72920.1 - 0.016 14.3 0.1 3 6.9 0.0 2.4 1 1 1 2 2 2 0 HlyD family secretion protein Pyridox_oxidase PF01243.15 EXF72921.1 - 8.2e-15 54.5 0.0 7.1e-14 51.5 0.0 2.1 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Pyridox_ox_2 PF12900.2 EXF72921.1 - 0.0015 18.3 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 2 Pyridoxamine 5'-phosphate oxidase Gpi16 PF04113.9 EXF72921.1 - 0.0034 15.4 0.0 0.0041 15.1 0.0 1.1 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Methyltransf_23 PF13489.1 EXF72922.1 - 3.5e-16 59.3 0.0 6.9e-16 58.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF72922.1 - 8.2e-10 39.0 0.1 3e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF72922.1 - 1.5e-08 35.2 0.0 5.5e-08 33.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF72922.1 - 5.6e-08 33.1 0.0 1.1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF72922.1 - 8.7e-08 31.8 0.0 4.1e-07 29.7 0.0 2.0 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF72922.1 - 1.2e-05 25.5 0.0 2.8e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF72922.1 - 0.0001 21.4 0.0 0.00076 18.5 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 EXF72922.1 - 0.00011 21.3 0.0 0.0003 19.9 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EXF72922.1 - 0.00023 20.5 0.0 0.00064 19.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EXF72922.1 - 0.0028 17.6 0.0 0.012 15.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EXF72922.1 - 0.078 12.0 0.0 0.18 10.8 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Gln-synt_C PF00120.19 EXF72923.1 - 4e-67 226.1 0.0 5e-67 225.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain adh_short PF00106.20 EXF72924.1 - 1.5e-25 90.0 3.4 1.9e-25 89.6 2.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF72924.1 - 4.6e-15 56.0 0.1 6.1e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF72924.1 - 7.2e-08 32.3 1.9 1.1e-07 31.7 1.3 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EXF72924.1 - 0.0001 22.0 0.2 0.00018 21.2 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EXF72924.1 - 0.00079 18.9 0.1 0.0012 18.3 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EXF72924.1 - 0.028 13.4 0.1 0.098 11.7 0.0 1.9 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Methyltransf_18 PF12847.2 EXF72924.1 - 0.043 14.3 0.0 0.17 12.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Polysacc_synt_2 PF02719.10 EXF72924.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EXF72924.1 - 0.24 11.1 1.9 0.84 9.4 0.7 2.2 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ICL PF00463.16 EXF72925.1 - 1.4e-202 673.5 0.2 1.6e-202 673.3 0.1 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EXF72925.1 - 2.4e-13 49.8 0.1 3.3e-11 42.8 0.0 2.4 2 0 0 2 2 2 2 Phosphoenolpyruvate phosphomutase Arg_repressor_C PF02863.13 EXF72925.1 - 0.11 12.0 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Arginine repressor, C-terminal domain Citrate_synt PF00285.16 EXF72926.1 - 1.1e-102 343.3 0.0 1.4e-102 343.1 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase DUF4360 PF14273.1 EXF72927.1 - 1.8e-72 242.8 2.5 2.1e-72 242.6 1.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) Sulfate_transp PF00916.15 EXF72928.1 - 1.8e-57 194.4 10.9 1.8e-57 194.4 7.6 1.6 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EXF72928.1 - 3e-29 100.4 3.1 3e-29 100.4 2.1 3.2 3 2 2 5 5 5 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EXF72928.1 - 1.7e-12 46.8 0.0 3.3e-12 45.8 0.0 1.5 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EXF72928.1 - 0.0029 17.5 0.0 0.007 16.3 0.0 1.6 1 0 0 1 1 1 1 STAS domain MotB_plug PF13677.1 EXF72928.1 - 0.93 8.8 4.4 1.1 8.5 1.9 2.0 2 0 0 2 2 2 0 Membrane MotB of proton-channel complex MotA/MotB MscS_TM PF12794.2 EXF72929.1 - 0.0021 16.7 0.3 0.0021 16.7 0.2 1.7 2 0 0 2 2 2 1 Mechanosensitive ion channel inner membrane domain 1 DUF4231 PF14015.1 EXF72929.1 - 6.3 6.8 10.7 12 5.8 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Lactamase_B PF00753.22 EXF72930.1 - 1.8e-21 76.7 3.3 2.5e-21 76.2 2.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EXF72930.1 - 0.009 15.5 0.2 0.014 14.9 0.2 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Scytalone_dh PF02982.9 EXF72930.1 - 0.021 14.4 0.0 0.047 13.2 0.0 1.5 1 0 0 1 1 1 0 Scytalone dehydratase ORF6C PF10552.4 EXF72930.1 - 0.082 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 ORF6C domain Pyr_redox_2 PF07992.9 EXF72931.1 - 1.1e-06 28.6 0.0 7.9e-06 25.8 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF72931.1 - 0.00086 19.1 0.0 0.0094 15.7 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EXF72931.1 - 0.00095 18.1 0.1 0.0032 16.4 0.1 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EXF72931.1 - 0.0028 17.7 0.0 0.041 13.9 0.0 2.1 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Malic_M PF03949.10 EXF72931.1 - 0.099 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Glyco_hydro_43 PF04616.9 EXF72932.1 - 0.014 14.4 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 43 Methyltransf_23 PF13489.1 EXF72933.1 - 1.1e-22 80.4 0.0 1.9e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF72933.1 - 1.8e-09 38.1 0.0 2.2e-08 34.6 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF72933.1 - 1.6e-06 28.4 0.0 3.1e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF72933.1 - 1.7e-06 28.4 0.0 5.2e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF72933.1 - 1.7e-06 27.6 0.0 1.2e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF72933.1 - 0.0024 18.2 0.0 0.0061 16.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF72933.1 - 0.0091 15.0 0.0 0.027 13.5 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 EXF72933.1 - 0.0098 15.9 0.0 0.085 12.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF72933.1 - 0.072 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.13 EXF72933.1 - 0.15 11.2 0.0 3.4 6.8 0.0 2.1 2 0 0 2 2 2 0 O-methyltransferase Fungal_trans PF04082.13 EXF72934.1 - 5.5e-31 107.3 0.0 8.8e-31 106.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF72934.1 - 1.4e-06 28.0 8.3 2.6e-06 27.2 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EXF72935.1 - 8.1e-18 64.8 0.0 3.4e-17 62.8 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF72935.1 - 7.4e-05 22.6 0.0 0.0011 18.7 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EXF72935.1 - 0.00014 21.4 0.0 0.00055 19.4 0.0 1.9 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EXF72935.1 - 0.00043 19.9 0.0 0.0011 18.6 0.0 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EXF72935.1 - 0.011 15.7 0.1 0.63 10.0 0.0 2.4 1 1 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EXF72935.1 - 0.074 12.8 0.2 0.22 11.3 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Abhydrolase_6 PF12697.2 EXF72937.1 - 6.3e-33 114.5 0.0 7.9e-33 114.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF72937.1 - 1e-26 93.9 0.0 2e-26 92.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF72937.1 - 2.6e-19 69.3 0.0 1.1e-17 64.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF72937.1 - 1.5e-07 30.9 0.0 0.011 14.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.5 EXF72937.1 - 2.3e-05 24.2 0.0 5.3e-05 23.0 0.0 1.5 2 0 0 2 2 2 1 TAP-like protein Ndr PF03096.9 EXF72937.1 - 4.1e-05 22.1 0.0 5e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 EXF72937.1 - 0.00028 20.6 0.1 0.0006 19.6 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_3 PF07859.8 EXF72937.1 - 0.00045 19.8 0.0 0.0014 18.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold FSH1 PF03959.8 EXF72937.1 - 0.0077 15.6 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 Serine hydrolase (FSH1) AXE1 PF05448.7 EXF72937.1 - 0.06 11.8 0.0 1.1 7.6 0.0 2.3 2 1 0 2 2 2 0 Acetyl xylan esterase (AXE1) UPF0227 PF05728.7 EXF72937.1 - 0.1 12.2 0.0 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) MFS_1 PF07690.11 EXF72938.1 - 2.6e-35 121.7 28.1 2.6e-35 121.7 19.5 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily zf-RING_6 PF14835.1 EXF72938.1 - 0.0083 15.8 1.7 0.038 13.7 0.1 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Cutinase PF01083.17 EXF72939.1 - 2.4e-31 108.8 7.5 3.4e-31 108.3 5.2 1.2 1 0 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 EXF72939.1 - 0.00018 21.1 0.2 0.00023 20.8 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF72939.1 - 0.002 17.9 0.6 0.0024 17.6 0.4 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF72939.1 - 0.0036 17.1 0.1 0.0049 16.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EXF72939.1 - 0.0051 16.2 0.0 0.0077 15.7 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 EXF72939.1 - 0.0061 16.1 0.1 0.0087 15.6 0.1 1.4 1 1 0 1 1 1 1 Lipase (class 3) PE-PPE PF08237.6 EXF72939.1 - 0.0072 15.7 0.3 0.0091 15.4 0.2 1.2 1 0 0 1 1 1 1 PE-PPE domain Thioesterase PF00975.15 EXF72939.1 - 0.027 14.6 0.1 0.037 14.2 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain PGAP1 PF07819.8 EXF72939.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein p450 PF00067.17 EXF72941.1 - 1.6e-70 237.9 0.0 2e-70 237.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_permease PF00324.16 EXF72943.1 - 6.7e-89 298.4 38.0 8.2e-89 298.1 26.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF72943.1 - 1.9e-25 89.2 40.1 2.4e-25 88.9 27.8 1.1 1 0 0 1 1 1 1 Amino acid permease Sulfotransfer_3 PF13469.1 EXF72944.1 - 0.042 14.7 0.0 0.082 13.8 0.0 1.6 1 1 0 1 1 1 0 Sulfotransferase family Thioredoxin PF00085.15 EXF72945.1 - 1.2e-23 82.7 0.0 3.5e-23 81.2 0.0 1.7 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_8 PF13905.1 EXF72945.1 - 9.4e-06 25.6 0.0 4e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EXF72945.1 - 1.4e-05 25.0 0.0 2.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EXF72945.1 - 4.9e-05 22.9 0.0 7.5e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Redoxin Thioredoxin_2 PF13098.1 EXF72945.1 - 8.6e-05 22.7 1.1 0.0015 18.7 0.8 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EXF72945.1 - 9.1e-05 22.1 0.0 0.0012 18.5 0.0 2.1 1 1 0 1 1 1 1 AhpC/TSA family HyaE PF07449.6 EXF72945.1 - 0.0028 17.5 0.0 0.0054 16.6 0.0 1.6 1 1 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_9 PF14595.1 EXF72945.1 - 0.012 15.1 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Ank_2 PF12796.2 EXF72946.1 - 1.8e-36 124.3 0.0 2.9e-19 69.1 0.0 2.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EXF72946.1 - 2.1e-33 112.4 0.1 5.3e-07 29.1 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EXF72946.1 - 1.5e-25 89.0 0.0 3.4e-12 46.5 0.0 4.3 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF72946.1 - 2e-25 88.2 1.9 5.7e-10 39.1 0.0 5.1 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF72946.1 - 2.2e-23 80.0 0.0 0.00015 21.6 0.0 6.4 7 0 0 7 7 7 5 Ankyrin repeat eIF-1a PF01176.14 EXF72946.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 HET PF06985.6 EXF72947.1 - 1.7e-32 112.4 0.5 3.5e-32 111.4 0.3 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 EXF72948.1 - 6.6e-21 74.4 26.1 1.1e-20 73.6 18.1 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EXF72948.1 - 3e-12 46.3 6.0 3e-12 46.3 4.2 3.2 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 7TM_GPCR_Sri PF10327.4 EXF72948.1 - 1.9 7.3 6.2 0.12 11.2 0.8 1.6 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Sri MerC PF03203.9 EXF72948.1 - 2.9 8.3 6.5 5 7.5 2.8 2.8 2 1 0 2 2 2 0 MerC mercury resistance protein Hydantoinase_B PF02538.9 EXF72949.1 - 1.6e-151 505.1 0.0 2.7e-151 504.4 0.0 1.3 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EXF72949.1 - 6.6e-82 274.8 0.0 1.2e-81 274.0 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EXF72949.1 - 3.1e-47 160.3 0.0 1.6e-44 151.4 0.0 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.4 EXF72949.1 - 0.015 14.5 0.0 0.039 13.2 0.0 1.7 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature RsgI_N PF12791.2 EXF72949.1 - 0.045 13.4 0.2 6.5 6.5 0.1 3.0 2 1 1 3 3 3 0 Anti-sigma factor N-terminus adh_short PF00106.20 EXF72950.1 - 5.5e-34 117.4 1.8 1.2e-33 116.4 1.2 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF72950.1 - 8.7e-31 107.5 1.5 1.2e-30 107.0 1.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF72950.1 - 5.7e-13 48.9 0.4 5.7e-13 48.9 0.2 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EXF72950.1 - 0.0082 15.5 0.1 0.013 14.9 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EXF72950.1 - 0.017 14.9 0.5 0.053 13.3 0.4 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EXF72950.1 - 0.062 12.4 0.0 0.48 9.5 0.0 2.0 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) HAD PF12710.2 EXF72950.1 - 0.091 12.9 0.1 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Aldedh PF00171.17 EXF72951.1 - 3.8e-149 496.9 0.0 4.5e-149 496.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EXF72951.1 - 0.03 13.0 0.1 0.076 11.7 0.0 1.7 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) Exo_endo_phos PF03372.18 EXF72953.1 - 3.3e-07 30.5 0.8 4.9e-07 29.9 0.5 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RasGEF PF00617.14 EXF72955.1 - 1.9e-54 184.2 0.0 5e-54 182.9 0.0 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EXF72955.1 - 3.1e-17 62.5 0.0 1.1e-16 60.8 0.0 1.9 2 0 0 2 2 2 1 RasGEF N-terminal motif SH3_9 PF14604.1 EXF72955.1 - 5.4e-06 25.8 0.0 1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EXF72955.1 - 3.9e-05 22.9 0.0 7.5e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain p450 PF00067.17 EXF72956.1 - 2.2e-63 214.3 0.0 2.5e-63 214.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C97 PF05903.9 EXF72957.1 - 1.3e-05 25.0 0.0 2.1e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4105 PF13387.1 EXF72957.1 - 0.002 17.3 0.2 0.003 16.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4105) LRAT PF04970.8 EXF72957.1 - 0.006 16.5 0.7 0.077 12.9 0.5 2.2 1 1 0 1 1 1 1 Lecithin retinol acyltransferase DUF778 PF05608.7 EXF72957.1 - 0.096 12.6 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF778) DUF4265 PF14085.1 EXF72959.1 - 0.0046 16.7 0.1 0.018 14.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4265) Na_Pi_cotrans PF02690.10 EXF72960.1 - 0.27 10.9 1.0 0.51 10.0 0.7 1.3 1 0 0 1 1 1 0 Na+/Pi-cotransporter HET PF06985.6 EXF72961.1 - 7e-27 94.2 0.0 1.6e-26 93.1 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FMO-like PF00743.14 EXF72962.1 - 7.4e-27 93.7 0.1 1.2e-19 69.9 0.0 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EXF72962.1 - 3.8e-15 56.5 0.0 6.3e-14 52.5 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF72962.1 - 1.5e-07 30.6 0.0 6.4e-06 25.3 0.0 2.5 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EXF72962.1 - 5.6e-06 26.3 0.0 0.00049 20.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF72962.1 - 2.6e-05 24.0 0.3 0.00012 21.8 0.2 2.1 1 1 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EXF72962.1 - 0.021 14.8 0.1 0.088 12.8 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EXF72962.1 - 0.11 11.5 0.0 0.26 10.3 0.0 1.6 2 0 0 2 2 2 0 Thi4 family MFS_1 PF07690.11 EXF72963.1 - 7.6e-21 74.2 19.4 1.9e-19 69.6 13.5 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Amino_oxidase PF01593.19 EXF72964.1 - 2.8e-41 142.0 0.1 2.8e-40 138.7 0.1 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EXF72964.1 - 4e-13 49.1 1.4 5.8e-13 48.6 0.2 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EXF72964.1 - 1.1e-08 34.3 3.1 1.8e-08 33.6 2.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EXF72964.1 - 2.1e-08 33.6 1.4 3.3e-08 33.0 1.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.19 EXF72964.1 - 2.2e-08 33.3 1.5 2.5e-08 33.2 0.3 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EXF72964.1 - 2.6e-07 29.9 0.5 4.5e-07 29.2 0.3 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EXF72964.1 - 1.1e-06 27.4 0.1 2e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EXF72964.1 - 1.4e-06 28.5 0.3 7e-06 26.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF72964.1 - 2.3e-06 27.6 0.0 7.8e-06 25.9 0.1 1.9 2 2 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF72964.1 - 2.5e-06 27.7 0.5 5e-05 23.6 0.1 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF72964.1 - 2.9e-06 26.3 0.1 4.9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EXF72964.1 - 7.4e-06 25.1 0.5 6.6e-05 22.0 0.2 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EXF72964.1 - 0.0024 16.9 1.1 0.0053 15.8 0.4 1.8 2 0 0 2 2 2 1 FAD binding domain 3HCDH_N PF02737.13 EXF72964.1 - 0.035 13.7 0.4 0.07 12.7 0.3 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EXF72964.1 - 0.21 11.1 4.5 0.18 11.3 0.4 2.6 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain PAH PF02671.16 EXF72965.1 - 6.7e-06 25.6 0.3 1.5e-05 24.5 0.2 1.6 1 1 0 1 1 1 1 Paired amphipathic helix repeat Fungal_trans_2 PF11951.3 EXF72966.1 - 6.3e-18 64.5 0.0 8.1e-14 51.0 0.1 2.0 1 1 1 2 2 2 2 Fungal specific transcription factor domain DUF2183 PF09949.4 EXF72968.1 - 2.6e-30 104.2 0.1 7.6e-30 102.7 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2183) Lactamase_B_2 PF12706.2 EXF72969.1 - 4.4e-21 75.3 0.0 5.3e-21 75.0 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EXF72969.1 - 1.2e-06 28.3 0.0 1.8e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Sugar_tr PF00083.19 EXF72970.1 - 4e-89 299.2 23.7 4.5e-89 299.0 16.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF72970.1 - 3e-21 75.5 38.7 7.7e-15 54.4 10.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EXF72970.1 - 0.011 13.8 1.4 0.15 10.0 0.1 2.3 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family ADH_zinc_N PF00107.21 EXF72971.1 - 2.8e-22 78.6 0.9 9.7e-22 76.9 0.6 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF72971.1 - 2.2e-20 72.4 1.7 9.3e-20 70.4 0.6 2.3 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EXF72971.1 - 3e-09 37.8 0.1 1.1e-08 35.9 0.0 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EXF72971.1 - 2.6e-05 23.8 0.4 4.8e-05 22.9 0.1 1.6 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 EXF72971.1 - 0.00012 21.5 0.3 0.00024 20.5 0.0 1.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 EXF72971.1 - 0.00019 21.2 0.2 0.00037 20.3 0.1 1.5 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_11 PF08241.7 EXF72971.1 - 0.0047 17.3 0.0 0.012 16.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF72971.1 - 0.0065 17.0 0.1 0.059 13.9 0.1 2.5 1 1 1 2 2 2 1 Methyltransferase domain 3HCDH_N PF02737.13 EXF72971.1 - 0.014 15.0 0.6 0.028 14.0 0.2 1.6 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EXF72971.1 - 0.015 14.5 0.1 0.022 13.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HET PF06985.6 EXF72973.1 - 1.2e-24 86.9 0.0 1.8e-23 83.2 0.0 2.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 EXF72974.1 - 2.3e-29 102.4 0.5 3e-29 102.0 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF72974.1 - 5.4e-25 88.5 0.0 7e-25 88.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF72974.1 - 6.2e-17 61.8 0.2 9.1e-17 61.3 0.1 1.2 1 0 0 1 1 1 1 KR domain Sugar_tr PF00083.19 EXF72975.1 - 9.2e-76 255.2 25.6 1.1e-75 254.9 17.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF72975.1 - 4.4e-25 88.1 31.3 8e-20 70.8 11.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EXF72975.1 - 7.6e-05 20.9 0.2 0.00017 19.8 0.2 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family DUF1049 PF06305.6 EXF72976.1 - 8.3 5.9 7.4 13 5.3 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) adh_short PF00106.20 EXF72977.1 - 6.8e-30 104.1 0.1 1.2e-29 103.3 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF72977.1 - 1.1e-21 77.6 0.0 5e-21 75.5 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF72977.1 - 4.6e-14 52.4 0.0 8e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF72977.1 - 5.7e-05 22.6 0.0 0.00021 20.8 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EXF72977.1 - 0.02 14.5 0.1 0.035 13.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EXF72977.1 - 0.028 14.8 0.1 0.058 13.8 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DFP PF04127.10 EXF72977.1 - 0.033 13.7 0.2 1.5 8.4 0.3 2.2 1 1 1 2 2 2 0 DNA / pantothenate metabolism flavoprotein Glyco_tranf_2_3 PF13641.1 EXF72977.1 - 0.04 13.7 0.0 0.36 10.5 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase like family 2 DUF1776 PF08643.5 EXF72977.1 - 0.041 13.0 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 EXF72977.1 - 0.072 11.9 0.0 0.089 11.6 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pro_Al_protease PF02983.9 EXF72978.1 - 0.57 10.1 3.0 2.4 8.1 0.3 2.3 2 0 0 2 2 2 0 Alpha-lytic protease prodomain DUF678 PF05077.7 EXF72980.1 - 0.26 11.3 4.8 0.3 11.1 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF678) SnoaL PF07366.7 EXF72981.1 - 0.0016 18.0 0.1 0.0027 17.2 0.0 1.4 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Fungal_trans PF04082.13 EXF72982.1 - 2.8e-07 29.6 0.0 4.8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF72982.1 - 4.4e-07 29.6 11.0 8.9e-07 28.7 7.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF442 PF04273.8 EXF72984.1 - 0.011 15.6 0.2 0.017 14.9 0.1 1.4 1 0 0 1 1 1 0 Putative phosphatase (DUF442) NmrA PF05368.8 EXF72985.1 - 1e-25 90.3 0.0 1.3e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF72985.1 - 1.3e-13 51.3 0.2 2.2e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EXF72985.1 - 0.00036 20.2 0.0 0.0013 18.4 0.0 1.8 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EXF72985.1 - 0.0063 16.4 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 EXF72985.1 - 0.037 14.3 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EXF72985.1 - 0.096 12.6 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 EXF72985.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 7TMR-DISM_7TM PF07695.6 EXF72986.1 - 0.034 13.8 0.2 0.038 13.6 0.2 1.2 1 0 0 1 1 1 0 7TM diverse intracellular signalling Sporozoite_P67 PF05642.6 EXF72988.1 - 6.6 4.4 9.7 8.8 4.0 6.8 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF4246 PF14033.1 EXF72989.1 - 3.2e-119 398.7 0.1 1.5e-77 261.3 0.0 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF4246) XH PF03469.9 EXF72989.1 - 0.16 11.6 1.8 0.84 9.2 0.2 2.2 2 0 0 2 2 2 0 XH domain APH PF01636.18 EXF72990.1 - 2.1e-10 40.7 2.4 2.9e-09 37.0 1.7 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EXF72990.1 - 0.055 13.0 0.0 0.78 9.2 0.0 2.2 2 0 0 2 2 2 0 Choline/ethanolamine kinase MFS_1 PF07690.11 EXF72991.1 - 5.2e-27 94.4 24.6 5.2e-27 94.4 17.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3292 PF11696.3 EXF72992.1 - 1.4e-247 822.7 0.0 1.4e-247 822.7 0.0 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3292) Pex24p PF06398.6 EXF72992.1 - 0.014 14.1 0.0 0.02 13.7 0.0 1.3 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF639 PF04842.7 EXF72992.1 - 0.091 10.9 1.7 0.14 10.2 1.2 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) Glyco_hydro_32N PF00251.15 EXF72993.1 - 4.1e-30 105.1 8.5 1.1e-19 70.9 2.7 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EXF72993.1 - 1e-08 35.3 0.0 2e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Spore_coat_CotO PF14153.1 EXF72994.1 - 0.39 10.1 8.5 0.54 9.6 5.9 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Sugar_tr PF00083.19 EXF72995.1 - 2.2e-98 329.7 29.1 2.7e-98 329.4 20.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF72995.1 - 1.5e-23 83.1 27.4 1.5e-23 83.1 19.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF983 PF06170.7 EXF72995.1 - 0.033 14.2 1.1 0.19 11.8 0.8 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF983) Colicin PF01024.14 EXF72995.1 - 0.036 13.6 1.9 4.4 6.8 0.4 2.4 2 0 0 2 2 2 0 Colicin pore forming domain 2TM PF13239.1 EXF72996.1 - 4.7 7.3 7.0 39 4.3 0.0 2.6 2 0 0 2 2 2 0 2TM domain GMC_oxred_N PF00732.14 EXF72998.1 - 1.2e-51 175.6 0.0 4e-51 173.9 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF72998.1 - 6.4e-32 110.8 0.1 1e-31 110.2 0.1 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EXF72998.1 - 8.3e-06 24.9 0.4 1.6e-05 24.0 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.17 EXF72998.1 - 0.00019 20.4 0.0 0.094 11.5 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EXF72998.1 - 0.00097 18.1 0.2 0.026 13.4 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF72998.1 - 0.086 12.8 0.0 0.24 11.4 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF72998.1 - 0.087 12.6 0.0 0.46 10.3 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Glyco_hydro_7 PF00840.15 EXF72999.1 - 1.7e-144 481.4 15.3 2e-144 481.1 10.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Phage_FRD3 PF05798.6 EXF72999.1 - 0.0076 16.5 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 Bacteriophage FRD3 protein HET PF06985.6 EXF73000.1 - 6.9e-26 91.0 0.0 1.9e-25 89.6 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FA_desaturase PF00487.19 EXF73001.1 - 6.2e-40 137.2 20.5 8.1e-40 136.8 14.2 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EXF73001.1 - 8.3e-10 38.3 0.0 1.8e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_S8e PF01201.17 EXF73002.1 - 0.0002 21.4 18.4 0.0013 18.8 12.8 2.0 1 1 0 1 1 1 1 Ribosomal protein S8e DUF2390 PF09523.5 EXF73002.1 - 0.98 9.6 6.0 1.9 8.7 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2390) DUF3959 PF13105.1 EXF73002.1 - 1.4 8.2 8.2 0.57 9.4 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) Mer2 PF09074.5 EXF73002.1 - 1.6 8.5 8.8 0.34 10.8 0.3 2.0 2 0 0 2 2 2 0 Mer2 Bud13 PF09736.4 EXF73002.1 - 5.1 7.3 14.9 2.8 8.2 8.9 1.5 1 1 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex Ribosomal_L21p PF00829.16 EXF73003.1 - 0.0074 16.4 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Pkinase PF00069.20 EXF73004.1 - 5.2e-46 156.8 0.0 8.2e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF73004.1 - 2.4e-19 69.4 0.0 3.6e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF73004.1 - 9.6e-05 21.4 0.0 0.00029 19.9 0.0 1.6 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 EXF73004.1 - 0.0061 16.3 0.0 1.6 8.3 0.0 2.6 1 1 0 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EXF73004.1 - 0.094 12.0 0.0 0.22 10.8 0.0 1.6 1 0 0 1 1 1 0 RIO1 family DUF3336 PF11815.3 EXF73004.1 - 0.2 11.1 0.0 0.4 10.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3336) Ribosomal_60s PF00428.14 EXF73005.1 - 6.1e-28 97.0 11.5 7.1e-28 96.8 8.0 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein SPT2 PF08243.6 EXF73006.1 - 3.1e-06 27.4 26.7 3.1e-06 27.4 18.5 3.3 3 1 0 3 3 3 1 SPT2 chromatin protein NUFIP1 PF10453.4 EXF73007.1 - 2.3e-07 30.1 0.0 9.4e-07 28.2 0.0 2.0 1 0 0 1 1 1 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) zf-CCCH PF00642.19 EXF73007.1 - 0.11 12.2 5.8 0.25 11.0 4.0 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) V_ATPase_I PF01496.14 EXF73007.1 - 8.1 4.1 5.3 11 3.7 3.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family RNA_pol_Rbc25 PF08292.7 EXF73008.1 - 1.7e-34 118.5 0.1 2.5e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EXF73008.1 - 8.6e-15 54.6 0.0 1.3e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 DUF106 PF01956.11 EXF73009.1 - 1.4e-54 184.1 0.7 1.7e-54 183.8 0.5 1.1 1 0 0 1 1 1 1 Integral membrane protein DUF106 SPC25 PF06703.6 EXF73010.1 - 3.1e-52 176.4 0.1 3.6e-52 176.2 0.1 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) MMS19_N PF14500.1 EXF73011.1 - 8.1e-50 169.5 0.0 1.9e-49 168.3 0.0 1.6 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II Cohesin_HEAT PF12765.2 EXF73011.1 - 0.044 13.7 0.9 0.48 10.4 0.2 2.9 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion THF_DHG_CYH PF00763.18 EXF73012.1 - 3.4e-21 75.4 0.1 5.2e-21 74.8 0.1 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EXF73012.1 - 4.8e-15 54.9 0.0 7.3e-09 34.9 0.0 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF1765 PF08578.5 EXF73014.1 - 1.8e-44 150.8 2.0 3.8e-44 149.7 1.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1765) SBF PF01758.11 EXF73016.1 - 5.3e-44 149.8 16.2 5.3e-44 149.8 11.2 1.8 2 0 0 2 2 2 1 Sodium Bile acid symporter family Cys_Met_Meta_PP PF01053.15 EXF73018.1 - 4.3e-139 463.0 0.2 4.9e-139 462.9 0.1 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EXF73018.1 - 2.1e-08 33.3 1.5 3.2e-08 32.7 0.5 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EXF73018.1 - 1.5e-07 30.7 0.2 2.4e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EXF73018.1 - 5.6e-07 28.9 1.0 1e-06 28.0 0.7 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.11 EXF73018.1 - 0.002 16.8 0.3 0.0034 16.1 0.2 1.3 1 0 0 1 1 1 1 Glycine cleavage system P-protein Beta_elim_lyase PF01212.16 EXF73018.1 - 0.003 16.7 0.4 0.006 15.7 0.2 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase 2-Hacid_dh PF00389.25 EXF73018.1 - 0.082 12.3 0.0 0.13 11.7 0.0 1.4 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain EST1_DNA_bind PF10373.4 EXF73019.1 - 3.8e-15 55.8 0.0 8.2e-15 54.7 0.0 1.7 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain F-box-like PF12937.2 EXF73020.1 - 0.039 13.6 0.7 0.039 13.6 0.5 1.9 2 0 0 2 2 2 0 F-box-like TPR_21 PF09976.4 EXF73021.1 - 6.3e-05 22.9 1.4 0.00026 20.9 0.2 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EXF73021.1 - 0.00011 21.6 1.2 0.00053 19.5 0.2 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EXF73021.1 - 0.00053 20.5 3.0 0.0007 20.1 0.3 2.5 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EXF73021.1 - 0.00082 19.6 2.8 0.0083 16.4 0.2 2.9 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EXF73021.1 - 0.0034 17.3 1.2 0.13 12.1 0.2 3.4 2 1 3 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.1 EXF73021.1 - 0.0066 16.9 1.0 1.1 10.1 0.0 3.8 2 1 2 4 4 3 1 Tetratricopeptide repeat Luciferase_N PF05295.6 EXF73021.1 - 0.016 15.0 0.2 2.6 7.9 0.1 2.5 2 0 0 2 2 2 0 Luciferase/LBP N-terminal domain TPR_2 PF07719.12 EXF73021.1 - 0.023 14.5 3.3 0.31 11.0 0.1 3.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EXF73021.1 - 0.028 14.1 1.5 1.2 9.1 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat RPN7 PF10602.4 EXF73021.1 - 0.032 13.6 0.6 0.21 10.9 0.1 2.5 3 1 0 3 3 3 0 26S proteasome subunit RPN7 TPR_1 PF00515.23 EXF73021.1 - 0.036 13.6 1.3 0.36 10.5 0.1 3.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EXF73021.1 - 0.11 12.4 1.8 15 5.6 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2247 PF10004.4 EXF73021.1 - 0.11 12.1 2.1 0.12 12.0 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2247) TPR_11 PF13414.1 EXF73021.1 - 0.13 11.9 2.1 0.81 9.3 0.1 2.9 2 1 2 4 4 4 0 TPR repeat DUF3295 PF11702.3 EXF73022.1 - 3e-19 69.4 1.9 3.5e-19 69.1 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF3425 PF11905.3 EXF73023.1 - 3.1e-06 27.1 1.3 9.8e-06 25.4 0.4 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF3425) Laminin_EGF PF00053.19 EXF73024.1 - 0.15 12.0 0.9 0.16 11.9 0.7 1.2 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) Methyltransf_23 PF13489.1 EXF73026.1 - 7.5e-13 48.5 0.0 2.3e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF73026.1 - 5.4e-07 29.3 0.0 0.00037 20.1 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EXF73026.1 - 6.3e-05 23.3 0.0 0.00025 21.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF73026.1 - 0.00067 20.0 0.0 0.0037 17.6 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF73026.1 - 0.0073 16.8 0.1 0.14 12.7 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF73026.1 - 0.036 14.4 0.0 0.19 12.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain His_Phos_1 PF00300.17 EXF73027.1 - 6.6e-25 88.0 0.0 8.6e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PaaSYMP PF14738.1 EXF73027.1 - 0.0062 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 Ank_2 PF12796.2 EXF73028.1 - 6.5e-23 80.8 0.1 1.9e-09 37.7 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EXF73028.1 - 2.8e-16 58.3 0.2 0.00098 18.8 0.0 5.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EXF73028.1 - 1.4e-12 47.7 0.5 6.8e-06 26.4 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF73028.1 - 1.8e-10 40.0 0.2 0.57 10.5 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EXF73028.1 - 1.3e-08 34.8 0.0 0.00025 21.1 0.0 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) DUF1771 PF08590.5 EXF73029.1 - 1.3e-23 82.7 11.4 1.3e-23 82.7 7.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EXF73029.1 - 5.2e-13 49.0 0.3 1.7e-12 47.3 0.2 1.9 1 0 0 1 1 1 1 Smr domain OmpH PF03938.9 EXF73029.1 - 2.6 7.9 13.6 0.48 10.3 3.3 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) zf-Tim10_DDP PF02953.10 EXF73030.1 - 2.5e-19 68.3 4.4 3.8e-19 67.7 3.0 1.3 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Folate_rec PF03024.9 EXF73030.1 - 0.026 14.1 2.0 0.027 14.0 1.4 1.0 1 0 0 1 1 1 0 Folate receptor family PCI PF01399.22 EXF73030.1 - 0.1 12.9 0.4 0.12 12.6 0.3 1.2 1 0 0 1 1 1 0 PCI domain DUF3793 PF12672.2 EXF73030.1 - 0.11 12.1 0.2 0.33 10.5 0.0 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3793) UPF0137 PF03677.8 EXF73030.1 - 0.15 11.5 1.3 0.29 10.6 0.9 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0137) Nup188 PF10487.4 EXF73031.1 - 1.4e-35 122.6 0.0 4.2e-35 120.9 0.0 1.8 1 1 0 1 1 1 1 Nucleoporin subcomplex protein binding to Pom34 IGPS PF00218.16 EXF73032.1 - 2.8e-96 321.4 0.1 4.3e-96 320.8 0.1 1.3 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PRAI PF00697.17 EXF73032.1 - 6.3e-52 176.0 0.0 5.1e-48 163.2 0.0 2.5 1 1 1 2 2 2 2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase GATase PF00117.23 EXF73032.1 - 2.5e-49 167.3 0.0 5.8e-49 166.1 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EXF73032.1 - 0.00011 21.7 0.1 0.00049 19.6 0.1 2.1 1 1 0 1 1 1 1 Peptidase C26 NanE PF04131.9 EXF73032.1 - 0.0032 16.4 0.0 0.77 8.7 0.0 3.2 3 0 0 3 3 3 1 Putative N-acetylmannosamine-6-phosphate epimerase FMN_dh PF01070.13 EXF73032.1 - 0.023 13.5 0.1 0.15 10.8 0.0 2.2 2 0 0 2 2 2 0 FMN-dependent dehydrogenase QRPTase_C PF01729.14 EXF73032.1 - 0.037 13.5 0.9 1.2 8.6 0.1 2.7 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.16 EXF73032.1 - 0.07 12.3 0.1 0.36 10.0 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein BRCT PF00533.21 EXF73033.1 - 8.7e-05 22.5 0.2 0.0002 21.4 0.1 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EXF73033.1 - 0.043 13.6 1.1 0.19 11.6 0.8 2.1 1 1 0 1 1 1 0 twin BRCT domain DUF2775 PF10950.3 EXF73033.1 - 3.8 7.7 9.0 2.1 8.6 2.1 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF2775) Herpes_gE PF02480.11 EXF73034.1 - 0.0002 19.7 0.0 0.00027 19.3 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Syndecan PF01034.15 EXF73034.1 - 0.0024 17.5 0.2 0.0037 16.8 0.2 1.3 1 0 0 1 1 1 1 Syndecan domain SKG6 PF08693.5 EXF73034.1 - 0.0062 15.8 3.8 0.011 15.0 2.6 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1191 PF06697.7 EXF73034.1 - 0.0064 15.3 0.0 0.0094 14.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Protocadherin PF08374.6 EXF73034.1 - 0.026 14.1 0.0 0.035 13.7 0.0 1.2 1 0 0 1 1 1 0 Protocadherin DUF3827 PF12877.2 EXF73034.1 - 0.026 12.6 0.0 0.036 12.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Adeno_E3_CR2 PF02439.10 EXF73034.1 - 0.033 13.7 0.2 0.062 12.8 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 EXF73034.1 - 0.056 13.8 0.0 0.087 13.2 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4328 PF14219.1 EXF73034.1 - 0.079 12.2 0.0 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) Herpes_gE PF02480.11 EXF73035.1 - 0.0047 15.2 0.1 0.0047 15.2 0.1 1.9 1 1 0 2 2 2 1 Alphaherpesvirus glycoprotein E Syndecan PF01034.15 EXF73035.1 - 0.17 11.5 1.2 0.37 10.4 0.8 1.5 1 0 0 1 1 1 0 Syndecan domain MaoC_dehydratas PF01575.14 EXF73036.1 - 2.4e-07 30.1 0.0 3.9e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EXF73036.1 - 0.1 12.3 0.0 4.7 7.0 0.0 2.5 3 0 0 3 3 3 0 N-terminal half of MaoC dehydratase eRF1_2 PF03464.10 EXF73037.1 - 1.7e-45 154.6 0.0 3.2e-45 153.7 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EXF73037.1 - 2.5e-40 137.2 0.7 4.9e-40 136.3 0.5 1.5 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EXF73037.1 - 7.5e-29 99.9 0.0 1.3e-28 99.1 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 DUF1770 PF08589.5 EXF73038.1 - 2e-30 105.3 1.6 2.6e-30 104.9 1.1 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1770) Nop14 PF04147.7 EXF73039.1 - 0.085 10.7 11.9 0.14 10.0 8.3 1.3 1 0 0 1 1 1 0 Nop14-like family Ribosomal_L2_C PF03947.13 EXF73040.1 - 3.7e-38 130.2 3.8 6.3e-38 129.5 2.6 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EXF73040.1 - 8.2e-15 54.5 0.1 1.6e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PfkB PF00294.19 EXF73041.1 - 4.1e-65 219.8 0.2 4.6e-65 219.6 0.1 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EXF73041.1 - 0.022 13.9 0.0 0.04 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase EST1_DNA_bind PF10373.4 EXF73042.1 - 9.4e-53 179.2 0.1 1.8e-52 178.2 0.1 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.4 EXF73042.1 - 2.7e-18 66.2 0.8 7.8e-18 64.7 0.1 2.2 2 0 0 2 2 2 1 Telomerase activating protein Est1 TPR_11 PF13414.1 EXF73042.1 - 0.0014 18.2 0.3 0.0039 16.8 0.1 1.8 2 0 0 2 2 2 1 TPR repeat G10 PF01125.12 EXF73044.1 - 1.6e-61 206.0 3.4 1.8e-61 205.9 2.4 1.0 1 0 0 1 1 1 1 G10 protein Complex1_LYR_2 PF13233.1 EXF73045.1 - 4.5e-06 27.0 0.0 5.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EXF73045.1 - 8e-05 22.3 0.2 0.00014 21.5 0.2 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EXF73045.1 - 0.00011 22.2 0.3 0.0002 21.4 0.2 1.6 1 1 0 1 1 1 1 Complex1_LYR-like RNA_pol_L_2 PF13656.1 EXF73046.1 - 4e-29 99.8 0.0 5.2e-29 99.5 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EXF73046.1 - 1.3e-09 37.0 0.0 1.7e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain CENP-B_dimeris PF09026.5 EXF73046.1 - 0.39 10.9 4.6 0.57 10.4 3.2 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Tankyrase_bdg_C PF15327.1 EXF73046.1 - 0.48 10.6 3.2 0.74 9.9 2.2 1.2 1 0 0 1 1 1 0 Tankyrase binding protein C terminal domain TRAP_alpha PF03896.11 EXF73046.1 - 0.91 8.4 3.2 1.2 8.1 2.2 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2890 PF11081.3 EXF73046.1 - 2 8.4 9.1 3.1 7.8 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) HSP90 PF00183.13 EXF73046.1 - 2.6 6.3 5.5 3.5 5.9 3.8 1.2 1 0 0 1 1 1 0 Hsp90 protein Daxx PF03344.10 EXF73046.1 - 6.4 5.1 10.2 7.2 4.9 7.1 1.1 1 0 0 1 1 1 0 Daxx Family Acetyltransf_3 PF13302.1 EXF73047.1 - 8e-18 64.9 0.2 3.8e-17 62.7 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EXF73047.1 - 2.4e-06 27.4 0.6 3.9e-06 26.7 0.4 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF73047.1 - 0.024 14.8 0.2 0.05 13.7 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TPR_11 PF13414.1 EXF73050.1 - 3.5e-09 36.1 15.4 5.8e-05 22.6 0.0 4.1 3 1 0 4 4 4 2 TPR repeat TPR_1 PF00515.23 EXF73050.1 - 3.7e-07 29.4 12.1 0.011 15.2 0.4 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EXF73050.1 - 5.7e-07 28.9 7.5 0.24 11.4 0.2 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 EXF73050.1 - 0.0066 16.5 2.5 0.0094 16.0 0.3 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EXF73050.1 - 0.35 11.1 2.4 1.5 9.1 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.11 EXF73051.1 - 2e-37 128.7 21.3 1.2e-28 99.8 1.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF73051.1 - 1.3e-08 33.8 8.8 1.3e-08 33.8 6.1 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EXF73051.1 - 0.00038 18.9 23.8 0.0012 17.3 4.2 3.1 2 1 1 3 3 3 2 MFS/sugar transport protein WD40 PF00400.27 EXF73052.1 - 5.3e-27 92.6 16.3 1.4e-09 37.4 0.2 7.1 6 0 0 6 6 6 5 WD domain, G-beta repeat NACHT PF05729.7 EXF73052.1 - 7.9e-13 48.4 0.0 2.6e-12 46.6 0.0 1.9 2 0 0 2 2 2 1 NACHT domain PD40 PF07676.7 EXF73052.1 - 0.00024 20.6 0.8 9.2 6.0 0.0 4.7 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat AAA_16 PF13191.1 EXF73052.1 - 0.0066 16.4 0.0 0.065 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EXF73052.1 - 0.019 15.1 0.1 0.13 12.4 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 EXF73052.1 - 0.05 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain DUF1933 PF09147.5 EXF73052.1 - 0.064 12.6 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) Herpes_IE2_3 PF03361.9 EXF73052.1 - 0.28 10.4 0.1 0.82 8.9 0.0 1.7 2 0 0 2 2 2 0 Herpes virus intermediate/early protein 2/3 ADH_N PF08240.7 EXF73054.1 - 2.7e-30 104.3 0.9 4.4e-30 103.6 0.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF73054.1 - 2.7e-19 68.9 0.0 4e-19 68.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EXF73054.1 - 0.00052 19.6 0.0 0.001 18.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N_2 PF13602.1 EXF73054.1 - 0.0021 18.9 0.0 0.0037 18.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Sen15 PF09631.5 EXF73055.1 - 6e-28 97.0 0.0 1.2e-27 96.0 0.0 1.5 1 1 0 1 1 1 1 Sen15 protein DUF2985 PF11204.3 EXF73056.1 - 1.2e-37 127.4 1.5 1.2e-37 127.4 1.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Nuc_sug_transp PF04142.10 EXF73057.1 - 2.4e-11 43.2 1.4 4.9e-11 42.2 0.9 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EXF73057.1 - 2.8e-07 30.6 25.1 0.00016 21.7 4.2 3.1 2 1 1 3 3 3 3 EamA-like transporter family TPT PF03151.11 EXF73057.1 - 0.0042 16.7 15.1 0.28 10.8 0.7 2.5 2 0 0 2 2 2 2 Triose-phosphate Transporter family PDR_assoc PF08370.6 EXF73057.1 - 9.5 5.8 13.1 3.6 7.1 0.1 3.9 4 0 0 4 4 4 0 Plant PDR ABC transporter associated Yippee-Mis18 PF03226.9 EXF73058.1 - 1.7e-23 82.4 1.0 1.9e-23 82.2 0.7 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HNH_5 PF14279.1 EXF73058.1 - 0.0067 16.4 0.4 0.6 10.1 0.0 2.2 2 0 0 2 2 2 1 HNH endonuclease DUF2039 PF10217.4 EXF73058.1 - 0.0087 16.0 1.9 0.033 14.2 0.0 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) zf-CHY PF05495.7 EXF73058.1 - 0.022 14.9 1.7 4.1 7.6 0.1 2.2 2 0 0 2 2 2 0 CHY zinc finger Evr1_Alr PF04777.8 EXF73058.1 - 0.029 14.2 1.5 0.92 9.4 0.1 2.1 1 1 1 2 2 2 0 Erv1 / Alr family RIG-I_C-RD PF11648.3 EXF73058.1 - 0.033 14.0 1.9 0.071 12.9 1.3 1.6 1 1 0 1 1 1 0 C-terminal domain of RIG-I DUF3268 PF11672.3 EXF73058.1 - 0.05 13.6 1.4 0.84 9.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3268) Endonuclease_7 PF02945.10 EXF73058.1 - 0.18 11.5 2.0 0.3 10.8 1.0 1.7 1 1 0 1 1 1 0 Recombination endonuclease VII Ferric_reduct PF01794.14 EXF73059.1 - 2.7e-20 72.7 7.9 2.7e-20 72.7 5.5 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EXF73059.1 - 1.9e-19 70.0 0.0 1.1e-16 61.0 0.0 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EXF73059.1 - 8e-15 54.6 0.0 2.2e-14 53.1 0.0 1.8 1 1 0 1 1 1 1 FAD-binding domain DUF4405 PF14358.1 EXF73059.1 - 7.4 6.7 10.8 7.5 6.7 0.7 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) CLU PF13236.1 EXF73061.1 - 1.7e-81 272.8 0.0 3.2e-81 271.9 0.0 1.5 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EXF73061.1 - 7.7e-51 172.3 1.3 2.2e-50 170.8 0.0 2.4 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 CLU_N PF15044.1 EXF73061.1 - 4.3e-25 87.6 0.1 1.1e-24 86.4 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_12 PF13424.1 EXF73061.1 - 4e-20 71.5 14.4 9e-09 35.1 0.4 3.7 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 EXF73061.1 - 2.3e-15 55.9 0.1 0.0013 18.6 0.0 4.3 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EXF73061.1 - 6.1e-05 22.5 5.9 0.072 12.7 0.2 3.5 3 0 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EXF73061.1 - 0.0031 17.3 6.5 0.11 12.4 0.1 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat CDC45 PF02724.9 EXF73061.1 - 0.019 12.9 13.3 0.03 12.3 9.2 1.2 1 0 0 1 1 1 0 CDC45-like protein TPR_8 PF13181.1 EXF73061.1 - 0.048 13.4 4.5 0.68 9.8 0.4 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DDHD PF02862.12 EXF73061.1 - 0.16 11.7 9.6 0.52 10.0 6.7 1.8 1 0 0 1 1 1 0 DDHD domain SAPS PF04499.10 EXF73061.1 - 0.19 10.3 6.4 0.33 9.5 4.4 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NPR3 PF03666.8 EXF73061.1 - 2 6.8 10.3 3.7 5.9 7.2 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Fork_head PF00250.13 EXF73062.1 - 9.4e-35 118.5 0.3 1.7e-34 117.6 0.2 1.4 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EXF73062.1 - 7.6e-08 32.3 0.0 1.8e-07 31.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain Tubulin_3 PF14881.1 EXF73063.1 - 4.7e-79 264.0 0.2 8.8e-79 263.1 0.1 1.4 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.4 EXF73063.1 - 1.6e-41 140.9 0.1 2.7e-41 140.2 0.0 1.4 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin PF00091.20 EXF73063.1 - 4.5e-08 33.1 0.0 0.00042 20.2 0.0 2.3 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain PAP_central PF04928.12 EXF73064.1 - 2e-99 331.5 0.0 2.8e-99 331.0 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EXF73064.1 - 5.2e-46 156.0 0.3 1.1e-45 155.0 0.2 1.6 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EXF73064.1 - 2.2e-07 31.1 0.0 5.2e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Septin PF00735.13 EXF73065.1 - 3.5e-19 68.8 0.0 2.9e-18 65.8 0.0 1.9 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EXF73065.1 - 9.6e-06 25.5 0.0 3.7e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EXF73065.1 - 0.00097 18.3 0.3 0.015 14.5 0.2 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EXF73065.1 - 0.017 15.2 0.2 0.066 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EXF73065.1 - 0.058 12.8 0.1 0.14 11.5 0.0 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EXF73065.1 - 0.062 13.2 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.12 EXF73065.1 - 0.065 12.7 0.3 4 6.9 0.1 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Miro PF08477.8 EXF73065.1 - 0.068 13.6 0.1 0.14 12.6 0.1 1.5 1 0 0 1 1 1 0 Miro-like protein ABC_tran PF00005.22 EXF73065.1 - 0.077 13.2 0.1 0.74 10.1 0.0 2.6 2 1 0 2 2 2 0 ABC transporter AAA PF00004.24 EXF73065.1 - 0.11 12.7 0.1 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EXF73065.1 - 0.14 11.7 0.1 0.25 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EXF73065.1 - 0.14 11.6 0.1 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.7 EXF73065.1 - 0.19 10.8 0.0 0.38 9.8 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Pkinase PF00069.20 EXF73066.1 - 3.1e-78 262.5 0.0 3.6e-78 262.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF73066.1 - 2.4e-38 131.6 0.0 3.2e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF73066.1 - 0.0028 16.6 0.0 0.0084 15.1 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EXF73066.1 - 0.0062 15.6 0.0 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EXF73066.1 - 0.017 14.8 0.0 0.083 12.6 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Acyltransferase PF01553.16 EXF73067.1 - 8.9e-07 28.4 0.0 1.3e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase zf-C3HC4_2 PF13923.1 EXF73068.1 - 0.0022 17.9 2.1 0.0044 17.0 1.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EXF73068.1 - 0.027 14.3 1.5 0.045 13.6 1.1 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EXF73068.1 - 0.044 13.4 1.8 0.044 13.4 1.3 1.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EXF73068.1 - 0.058 13.2 0.9 0.11 12.3 0.6 1.4 1 0 0 1 1 1 0 Ring finger domain Mito_carr PF00153.22 EXF73069.1 - 3.6e-42 141.9 0.4 1.2e-15 57.0 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein SCA7 PF08313.7 EXF73070.1 - 1.1e-34 117.8 0.6 3.5e-34 116.2 0.4 1.9 1 0 0 1 1 1 1 SCA7, zinc-binding domain DUF2457 PF10446.4 EXF73070.1 - 1.6 7.3 25.5 0.048 12.3 12.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) DUF605 PF04652.11 EXF73071.1 - 0.15 11.4 5.9 0.21 10.9 4.1 1.2 1 0 0 1 1 1 0 Vta1 like Dickkopf_N PF04706.7 EXF73071.1 - 0.31 11.2 6.6 0.56 10.4 4.6 1.4 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region Lipase_GDSL_2 PF13472.1 EXF73072.1 - 3e-14 53.5 0.0 4.5e-13 49.7 0.0 2.1 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EXF73072.1 - 0.019 14.8 0.1 0.053 13.3 0.0 1.8 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase zf-C2H2_4 PF13894.1 EXF73073.1 - 8.1e-08 32.0 13.1 0.076 13.3 0.2 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EXF73073.1 - 0.017 15.4 2.1 6.6 7.2 0.0 3.1 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2 PF00096.21 EXF73073.1 - 0.021 15.1 20.4 0.34 11.3 0.5 4.5 4 1 0 4 4 4 0 Zinc finger, C2H2 type Patatin PF01734.17 EXF73075.1 - 2.8e-27 95.9 0.0 6e-27 94.9 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase Fungal_trans_2 PF11951.3 EXF73076.1 - 7.4e-11 41.2 0.0 4.1e-10 38.8 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain MatE PF01554.13 EXF73077.1 - 1.9e-45 154.3 25.6 6.1e-26 90.9 2.3 2.4 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.1 EXF73077.1 - 5.6e-07 29.4 6.0 5.6e-07 29.4 4.2 4.2 2 2 1 4 4 4 2 Polysaccharide biosynthesis C-terminal domain GFO_IDH_MocA PF01408.17 EXF73078.1 - 5e-19 68.9 0.0 8.8e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EXF73078.1 - 0.0081 15.9 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain PseudoU_synth_2 PF00849.17 EXF73079.1 - 8.3e-32 110.2 0.0 1.2e-31 109.7 0.0 1.2 1 0 0 1 1 1 1 RNA pseudouridylate synthase Ub-Mut7C PF14451.1 EXF73079.1 - 0.0029 17.0 0.1 0.0069 15.8 0.0 1.6 1 0 0 1 1 1 1 Mut7-C ubiquitin Fez1 PF06818.10 EXF73080.1 - 0.0058 16.6 2.0 0.0066 16.4 1.4 1.1 1 0 0 1 1 1 1 Fez1 Cpl-7 PF08230.6 EXF73080.1 - 0.014 15.1 0.7 0.18 11.5 0.1 2.6 2 1 0 2 2 2 0 Cpl-7 lysozyme C-terminal domain DUF603 PF04645.7 EXF73080.1 - 0.051 13.5 1.9 0.1 12.5 1.3 1.5 1 1 0 1 1 1 0 Protein of unknown function, DUF603 Pox_A11 PF05061.8 EXF73080.1 - 0.055 12.5 0.6 0.064 12.3 0.4 1.1 1 0 0 1 1 1 0 Poxvirus A11 Protein Golgin_A5 PF09787.4 EXF73080.1 - 0.071 11.6 4.9 0.16 10.4 3.4 1.6 1 1 0 1 1 1 0 Golgin subfamily A member 5 Tropomyosin_1 PF12718.2 EXF73080.1 - 0.081 12.7 3.1 0.14 12.0 2.2 1.5 1 1 0 1 1 1 0 Tropomyosin like BLOC1_2 PF10046.4 EXF73080.1 - 0.12 12.5 1.2 0.16 12.1 0.6 1.5 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Mito_fiss_reg PF05308.6 EXF73080.1 - 0.19 11.0 1.9 0.26 10.6 1.1 1.4 1 1 0 1 1 1 0 Mitochondrial fission regulator IncA PF04156.9 EXF73080.1 - 0.3 10.6 3.7 0.49 9.9 0.2 1.7 1 1 0 1 1 1 0 IncA protein Fib_alpha PF08702.5 EXF73080.1 - 0.31 11.1 3.6 0.97 9.5 2.5 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family TMF_DNA_bd PF12329.3 EXF73080.1 - 0.35 10.7 3.2 0.53 10.1 1.2 2.0 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding FlxA PF14282.1 EXF73080.1 - 1.4 8.9 6.3 1.4 8.8 1.7 2.1 1 1 1 2 2 2 0 FlxA-like protein GCV_T_C PF08669.6 EXF73081.1 - 5.5e-12 45.5 0.0 1.4e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Fungal_trans PF04082.13 EXF73081.1 - 3.7e-11 42.3 1.3 3e-10 39.4 0.9 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EXF73081.1 - 0.016 15.4 2.9 0.016 15.4 2.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF73081.1 - 0.019 15.2 2.8 0.019 15.2 1.9 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-met PF12874.2 EXF73081.1 - 0.46 10.7 2.9 0.24 11.6 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger of C2H2 type p450 PF00067.17 EXF73082.1 - 5.2e-38 130.7 0.0 7e-38 130.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF2404 PF10296.4 EXF73082.1 - 0.14 12.3 0.0 0.36 10.9 0.0 1.7 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) COesterase PF00135.23 EXF73083.1 - 2e-84 284.2 0.0 2.9e-84 283.6 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF73083.1 - 0.0098 15.4 6.5 0.088 12.3 3.9 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EXF73083.1 - 0.052 12.7 1.7 0.14 11.3 1.0 1.8 1 1 1 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EXF73084.1 - 6.1e-28 97.8 0.0 8.4e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EXF73084.1 - 1.3e-12 47.0 0.0 7.9e-12 44.4 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) DUF3089 PF11288.3 EXF73084.1 - 0.00011 21.3 0.0 0.00022 20.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Abhydrolase_5 PF12695.2 EXF73084.1 - 0.0073 16.0 0.1 0.0097 15.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF73084.1 - 0.12 11.6 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.23 EXF73084.1 - 0.14 10.8 0.2 0.3 9.7 0.2 1.4 1 1 0 1 1 1 0 Carboxylesterase family Vma12 PF11712.3 EXF73085.1 - 1.5 8.5 3.2 7.9 6.1 0.1 2.6 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase COesterase PF00135.23 EXF73086.1 - 5.6e-77 259.6 0.0 3.2e-76 257.1 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF73086.1 - 6.2e-08 32.4 0.7 8.7e-06 25.4 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EXF73086.1 - 0.0011 18.2 0.1 0.0019 17.4 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family FAD_binding_4 PF01565.18 EXF73087.1 - 7.4e-17 61.1 3.6 1.7e-16 59.9 1.8 2.2 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.7 EXF73087.1 - 1.3e-09 37.8 1.4 1.4e-09 37.6 0.1 1.8 2 0 0 2 2 2 1 Berberine and berberine like PhyH PF05721.8 EXF73088.1 - 1.5e-17 64.3 0.0 2.3e-17 63.7 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) SCP2 PF02036.12 EXF73088.1 - 2.1e-05 24.7 0.0 3.8e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 SCP-2 sterol transfer family Epimerase PF01370.16 EXF73089.1 - 3.6e-17 62.5 0.0 4.9e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EXF73089.1 - 3e-12 45.8 0.0 3.8e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EXF73089.1 - 6.4e-10 38.3 0.2 4.6e-09 35.5 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EXF73089.1 - 6.8e-10 39.2 0.3 5.8e-09 36.2 0.2 2.2 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EXF73089.1 - 1.3e-05 25.1 1.9 9.2e-05 22.4 1.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EXF73089.1 - 4.6e-05 22.7 0.5 9.9e-05 21.6 0.3 1.6 2 0 0 2 2 2 1 NmrA-like family KR PF08659.5 EXF73089.1 - 0.00024 20.8 1.4 0.002 17.8 0.9 2.1 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EXF73089.1 - 0.00038 19.4 0.3 0.0014 17.6 0.1 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Mem_trans PF03547.13 EXF73090.1 - 2.7e-27 95.0 1.4 3.5e-27 94.6 1.0 1.2 1 0 0 1 1 1 1 Membrane transport protein DUF2457 PF10446.4 EXF73090.1 - 4.7 5.8 6.7 6.7 5.3 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) ECH PF00378.15 EXF73091.1 - 4.3e-46 157.0 0.0 7.5e-43 146.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family RapA_C PF12137.3 EXF73092.1 - 0.0046 15.8 0.1 0.0052 15.6 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase recycling family C-terminal Apolipoprotein PF01442.13 EXF73092.1 - 0.0087 15.5 0.5 0.011 15.2 0.4 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Borrelia_P83 PF05262.6 EXF73092.1 - 0.015 13.5 4.9 0.016 13.5 3.4 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein SurE PF01975.12 EXF73092.1 - 0.038 13.2 0.0 0.041 13.1 0.0 1.3 1 0 0 1 1 1 0 Survival protein SurE CsbD PF05532.7 EXF73092.1 - 0.043 13.4 19.4 7.3 6.3 6.7 3.5 1 1 1 2 2 2 0 CsbD-like DUF883 PF05957.8 EXF73092.1 - 0.084 13.2 4.7 0.11 12.8 1.6 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) WXG100 PF06013.7 EXF73092.1 - 0.16 12.0 2.6 0.31 11.0 1.1 1.8 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DivIVA PF05103.8 EXF73092.1 - 0.25 11.3 5.0 0.77 9.8 3.5 1.8 1 1 0 1 1 1 0 DivIVA protein DUF809 PF05663.6 EXF73092.1 - 0.78 9.6 3.8 0.9 9.4 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF809) YtxH PF12732.2 EXF73092.1 - 1 9.7 8.5 43 4.5 5.9 2.3 1 1 0 1 1 1 0 YtxH-like protein LEA_4 PF02987.11 EXF73092.1 - 2.9 7.8 16.2 0.096 12.5 6.3 2.2 3 1 0 3 3 3 0 Late embryogenesis abundant protein DUF4470 PF14737.1 EXF73094.1 - 7.6e-20 70.5 0.0 1.6e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.13 EXF73094.1 - 1.5e-11 43.9 12.7 3e-11 43.0 8.8 1.5 1 0 0 1 1 1 1 MYND finger HET PF06985.6 EXF73095.1 - 6.5e-21 74.9 3.4 7.1e-17 61.8 0.2 2.3 1 1 0 2 2 2 2 Heterokaryon incompatibility protein (HET) ERp29_N PF07912.8 EXF73095.1 - 0.033 14.1 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 ERp29, N-terminal domain WSC PF01822.14 EXF73096.1 - 1.9e-11 43.7 9.9 1.9e-11 43.7 6.9 1.9 2 0 0 2 2 2 1 WSC domain SKG6 PF08693.5 EXF73096.1 - 3.8e-09 35.6 2.2 3.8e-09 35.6 1.5 2.3 3 0 0 3 3 3 1 Transmembrane alpha-helix domain DUF1191 PF06697.7 EXF73096.1 - 0.0011 17.8 0.5 0.0016 17.2 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Alpha_GJ PF03229.8 EXF73096.1 - 0.0038 17.5 6.4 0.0038 17.5 4.4 2.0 2 0 0 2 2 2 1 Alphavirus glycoprotein J DUF4366 PF14283.1 EXF73096.1 - 0.0038 16.6 0.3 0.0038 16.6 0.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) Peptidase_M56 PF05569.6 EXF73096.1 - 0.041 12.8 0.1 0.061 12.2 0.1 1.2 1 0 0 1 1 1 0 BlaR1 peptidase M56 EphA2_TM PF14575.1 EXF73096.1 - 0.066 13.6 0.0 0.24 11.8 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Podoplanin PF05808.6 EXF73096.1 - 0.26 10.8 10.7 0.12 11.9 3.6 2.1 2 0 0 2 2 2 0 Podoplanin Rab5ip PF07019.7 EXF73096.1 - 0.38 10.9 1.8 1 9.5 0.6 2.0 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) Adeno_E3_CR2 PF02439.10 EXF73096.1 - 1.2 8.7 3.5 1.3 8.6 0.4 2.2 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 Conotoxin PF02950.12 EXF73100.1 - 0.043 14.6 0.8 0.059 14.1 0.5 1.4 1 0 0 1 1 1 0 Conotoxin UPF0506 PF11703.3 EXF73100.1 - 0.88 9.5 4.6 17 5.4 3.2 2.2 1 1 1 2 2 2 0 UPF0506 Toxin_30 PF08117.6 EXF73100.1 - 4.6 7.3 8.3 9.2 6.4 5.7 1.6 1 1 0 1 1 1 0 Ptu family zf-H2C2 PF09337.5 EXF73101.1 - 2.7e-20 71.5 4.4 5.4e-20 70.5 3.1 1.5 1 0 0 1 1 1 1 His(2)-Cys(2) zinc finger Acetyltransf_4 PF13420.1 EXF73101.1 - 0.00053 19.9 0.0 0.00095 19.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EXF73101.1 - 0.0052 16.7 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EXF73101.1 - 0.0074 16.4 0.0 0.015 15.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ribosomal_S2 PF00318.15 EXF73102.1 - 4.5e-49 166.5 0.0 9e-49 165.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S2 CBS PF00571.23 EXF73102.1 - 8.5e-40 134.2 5.0 4.8e-10 39.0 0.0 4.8 4 0 0 4 4 4 4 CBS domain PB1 PF00564.19 EXF73102.1 - 2.5e-08 33.4 0.0 7.3e-08 31.9 0.0 1.9 2 0 0 2 2 2 1 PB1 domain PBP1_TM PF14812.1 EXF73102.1 - 0.03 14.6 0.3 0.03 14.6 0.2 1.9 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-H2C2_2 PF13465.1 EXF73103.1 - 1e-08 34.9 17.0 0.00024 21.2 0.1 4.5 4 0 0 4 4 4 2 Zinc-finger double domain zf-C2H2 PF00096.21 EXF73103.1 - 3.8e-08 33.2 25.5 0.00033 20.8 3.7 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF73103.1 - 0.0042 17.3 20.9 0.16 12.3 0.1 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger Cpn60_TCP1 PF00118.19 EXF73104.1 - 2e-139 465.3 5.9 2.3e-139 465.1 4.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family HET PF06985.6 EXF73105.1 - 2.2e-31 108.9 0.4 4.8e-31 107.7 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1626 PF07788.6 EXF73105.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1626) adh_short_C2 PF13561.1 EXF73106.1 - 4.7e-30 105.1 0.2 5.8e-30 104.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EXF73106.1 - 4e-22 78.9 5.0 6e-22 78.3 3.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF73106.1 - 1e-05 25.2 4.1 2.5e-05 24.0 2.9 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF73106.1 - 0.00069 19.1 0.2 0.14 11.5 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EXF73106.1 - 0.0025 16.8 0.2 0.0033 16.4 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3HCDH_N PF02737.13 EXF73106.1 - 0.017 14.7 1.9 0.027 14.1 1.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EXF73106.1 - 0.049 13.6 0.5 0.077 12.9 0.3 1.3 1 0 0 1 1 1 0 TrkA-N domain THF_DHG_CYH_C PF02882.14 EXF73106.1 - 0.078 12.0 0.2 0.13 11.3 0.2 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HEM4 PF02602.10 EXF73106.1 - 0.24 10.5 2.9 5.5 6.1 0.3 2.1 2 0 0 2 2 2 0 Uroporphyrinogen-III synthase HemD AdoHcyase_NAD PF00670.16 EXF73106.1 - 0.67 9.7 3.3 0.96 9.2 1.6 1.7 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain p450 PF00067.17 EXF73107.1 - 2.8e-29 101.9 0.0 1.6e-25 89.5 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Metalloenzyme PF01676.13 EXF73108.1 - 1e-70 237.9 0.2 1.2e-70 237.7 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.8 EXF73108.1 - 3.1e-70 235.9 0.0 4.3e-70 235.5 0.0 1.2 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.17 EXF73108.1 - 2e-07 30.6 0.0 4e-07 29.6 0.0 1.5 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EXF73108.1 - 2.1e-06 27.1 0.0 2e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 Sulfatase AP_endonuc_2 PF01261.19 EXF73108.1 - 0.0031 16.8 0.0 0.0065 15.7 0.0 1.4 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel STAT_int PF02865.12 EXF73108.1 - 0.042 13.8 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 STAT protein, protein interaction domain Med9 PF07544.8 EXF73109.1 - 9.2e-25 86.1 0.1 1.9e-24 85.1 0.1 1.5 2 0 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Fib_alpha PF08702.5 EXF73109.1 - 0.0024 17.9 0.5 0.0044 17.1 0.4 1.3 1 0 0 1 1 1 1 Fibrinogen alpha/beta chain family DUF16 PF01519.11 EXF73109.1 - 0.0063 16.7 1.2 0.0083 16.3 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF16 NPV_P10 PF05531.7 EXF73109.1 - 0.011 15.9 0.4 0.05 13.8 0.1 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Phage_GP20 PF06810.6 EXF73109.1 - 0.014 14.8 0.9 0.02 14.3 0.6 1.1 1 0 0 1 1 1 0 Phage minor structural protein GP20 IncA PF04156.9 EXF73109.1 - 0.025 14.1 1.3 0.043 13.4 0.9 1.3 1 0 0 1 1 1 0 IncA protein BLOC1_2 PF10046.4 EXF73109.1 - 0.056 13.5 0.3 0.086 12.9 0.2 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cob_adeno_trans PF01923.13 EXF73109.1 - 0.071 12.9 0.1 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Cobalamin adenosyltransferase FlxA PF14282.1 EXF73109.1 - 0.13 12.2 0.2 0.13 12.2 0.1 1.5 2 0 0 2 2 2 0 FlxA-like protein Med21 PF11221.3 EXF73109.1 - 0.15 12.0 2.6 0.2 11.6 1.8 1.4 1 1 0 1 1 1 0 Subunit 21 of Mediator complex V_ATPase_I PF01496.14 EXF73109.1 - 0.23 9.2 0.4 0.28 8.9 0.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SlyX PF04102.7 EXF73109.1 - 0.24 11.7 4.7 1.2 9.5 2.5 2.4 2 1 1 3 3 3 0 SlyX DUF4140 PF13600.1 EXF73109.1 - 1.7 9.1 5.4 8.7 6.8 3.8 2.1 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) TBCC PF07986.7 EXF73110.1 - 1.6e-31 108.1 0.2 2.5e-31 107.5 0.1 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C NPV_P10 PF05531.7 EXF73110.1 - 0.37 11.0 1.8 5.4 7.3 0.2 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein OMP_b-brl PF13505.1 EXF73112.1 - 0.94 9.3 11.1 2.9 7.7 7.7 1.8 1 1 0 1 1 1 0 Outer membrane protein beta-barrel domain LRR_6 PF13516.1 EXF73114.1 - 1.2e-16 58.8 1.2 0.0032 17.3 0.1 6.9 7 0 0 7 7 7 4 Leucine Rich repeat LRR_4 PF12799.2 EXF73114.1 - 4.6e-06 26.1 0.5 0.38 10.4 0.1 4.1 3 2 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EXF73114.1 - 0.00015 21.2 0.1 4 7.8 0.0 5.2 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_7 PF13504.1 EXF73114.1 - 0.029 14.5 3.1 41 5.0 0.0 5.2 5 0 0 5 5 5 0 Leucine rich repeat MOZ_SAS PF01853.13 EXF73115.1 - 2.2e-46 157.4 0.0 9.8e-46 155.3 0.0 2.0 1 1 0 1 1 1 1 MOZ/SAS family adh_short PF00106.20 EXF73117.1 - 1.4e-17 64.0 0.0 1.8e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF73117.1 - 1.1e-05 25.3 0.0 1.3e-05 25.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF73117.1 - 0.0012 18.5 0.0 0.0016 18.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Slu7 PF11708.3 EXF73119.1 - 0.16 11.6 3.9 0.16 11.7 1.8 1.6 1 1 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor DUF1664 PF07889.7 EXF73119.1 - 1.4 8.7 4.3 1.6 8.5 0.5 2.8 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) PilJ PF13675.1 EXF73119.1 - 1.7 9.0 6.2 35 4.7 0.1 3.5 4 0 0 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term Allexi_40kDa PF05549.6 EXF73119.1 - 1.9 7.7 5.4 0.77 9.0 0.3 2.5 2 1 1 3 3 3 0 Allexivirus 40kDa protein KGG PF10685.4 EXF73120.1 - 4.3e-43 144.4 22.8 1.4e-09 37.6 0.1 5.2 5 0 0 5 5 5 5 Stress-induced bacterial acidophilic repeat motif VanY PF02557.12 EXF73120.1 - 7.7 6.3 8.3 30 4.4 0.2 2.9 1 1 1 2 2 2 0 D-alanyl-D-alanine carboxypeptidase Peptidase_C48 PF02902.14 EXF73121.1 - 1.3e-16 60.9 0.0 3.1e-16 59.6 0.0 1.6 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain RRM_6 PF14259.1 EXF73122.1 - 2.1e-05 24.3 0.1 9.4e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF4061 PF13270.1 EXF73122.1 - 0.12 12.4 4.5 0.1 12.7 1.2 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) DUF972 PF06156.8 EXF73122.1 - 3.3 8.0 8.6 22 5.4 1.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 EXF73122.1 - 7.1 6.1 14.2 18 4.8 9.7 1.7 1 1 0 1 1 1 0 IncA protein PIP5K PF01504.13 EXF73123.1 - 1.4e-35 122.6 0.0 1.8e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase HET PF06985.6 EXF73124.1 - 1.8e-22 79.9 0.1 3.2e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ACOX PF01756.14 EXF73125.1 - 1e-38 132.5 0.3 2e-38 131.6 0.2 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EXF73125.1 - 1.2e-29 103.1 0.5 2.7e-29 102.0 0.1 1.8 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EXF73125.1 - 6.8e-13 47.9 0.5 2e-12 46.3 0.1 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EXF73125.1 - 1.2e-06 28.7 0.8 0.0013 18.8 0.0 3.1 3 0 0 3 3 3 2 Acyl-CoA dehydrogenase, C-terminal domain Terpene_synth_C PF03936.11 EXF73126.1 - 1.9e-10 40.4 1.4 2.5e-10 40.0 0.4 1.5 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain DFF-C PF09033.5 EXF73126.1 - 0.046 13.5 0.6 0.08 12.7 0.4 1.3 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain Pec_lyase_C PF00544.14 EXF73127.1 - 1.2e-37 129.3 13.7 9.3e-37 126.4 9.5 2.1 1 1 0 1 1 1 1 Pectate lyase Gly_transf_sug PF04488.10 EXF73128.1 - 4.9e-11 42.9 0.2 4.9e-11 42.9 0.1 2.0 2 0 0 2 2 2 1 Glycosyltransferase sugar-binding region containing DXD motif DUF3106 PF11304.3 EXF73128.1 - 0.011 16.0 4.2 0.024 15.0 2.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3106) Caps_synth PF05704.7 EXF73128.1 - 0.25 10.4 0.0 0.25 10.4 0.0 2.0 2 0 0 2 2 2 0 Capsular polysaccharide synthesis protein Acyl_transf_3 PF01757.17 EXF73129.1 - 5e-36 124.2 30.8 7.5e-36 123.6 21.3 1.2 1 0 0 1 1 1 1 Acyltransferase family p450 PF00067.17 EXF73132.1 - 9.1e-31 106.8 0.0 1.1e-30 106.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Torsin PF06309.6 EXF73134.1 - 0.063 13.1 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 Torsin IgG_binding_B PF01378.12 EXF73134.1 - 2.5 7.9 6.0 11 5.9 0.1 2.9 3 0 0 3 3 3 0 B domain E1-E2_ATPase PF00122.15 EXF73135.1 - 2.6e-57 193.4 2.5 6.8e-57 192.1 1.8 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EXF73135.1 - 3.2e-44 150.6 6.8 3.2e-44 150.6 4.7 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EXF73135.1 - 5.5e-32 111.9 0.2 1.3e-31 110.6 0.2 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EXF73135.1 - 1.9e-18 66.1 0.0 4.2e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EXF73135.1 - 1.2e-13 51.7 0.0 2.5e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EXF73135.1 - 7.9e-12 44.4 0.0 4.2e-10 38.9 0.0 2.8 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EXF73135.1 - 8.9e-05 22.1 0.1 0.00039 20.0 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Sugar_tr PF00083.19 EXF73136.1 - 4.6e-113 378.1 19.0 5.2e-113 377.9 13.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF73136.1 - 2.3e-27 95.6 48.7 4.1e-26 91.5 13.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SUI1 PF01253.17 EXF73137.1 - 0.1 12.3 0.1 0.18 11.6 0.1 1.3 1 0 0 1 1 1 0 Translation initiation factor SUI1 Abhydrolase_6 PF12697.2 EXF73138.1 - 5.8e-32 111.4 0.7 9.2e-32 110.7 0.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF73138.1 - 1e-18 67.7 0.5 2.2e-18 66.6 0.3 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF73138.1 - 3e-11 43.2 0.0 7.6e-11 41.9 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EXF73138.1 - 0.00027 20.7 0.0 0.00044 20.0 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 EXF73138.1 - 0.0058 15.1 0.0 0.0076 14.7 0.0 1.1 1 0 0 1 1 1 1 Ndr family EHN PF06441.7 EXF73138.1 - 0.054 13.4 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 Epoxide hydrolase N terminus DUF1057 PF06342.7 EXF73138.1 - 0.17 10.6 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) BH4 PF02180.12 EXF73139.1 - 0.11 12.0 0.1 0.11 12.0 0.0 2.4 2 0 0 2 2 2 0 Bcl-2 homology region 4 HET PF06985.6 EXF73142.1 - 1.8e-08 34.6 0.3 1.9e-06 28.1 0.2 2.9 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Exo_endo_phos PF03372.18 EXF73143.1 - 3.8e-09 36.8 0.1 5.2e-09 36.3 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribonuc_L-PSP PF01042.16 EXF73144.1 - 1.1e-15 57.4 0.0 1.3e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Sulfotransfer_3 PF13469.1 EXF73145.1 - 0.11 13.4 0.0 0.29 12.0 0.0 1.7 1 1 0 1 1 1 0 Sulfotransferase family UDPGT PF00201.13 EXF73146.1 - 7.6e-20 70.9 0.0 2.4e-17 62.6 0.0 2.2 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 EXF73146.1 - 4.3e-08 32.7 0.0 0.00018 20.8 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 1 Glyco_transf_28 PF03033.15 EXF73146.1 - 1.5e-07 31.2 0.3 3.8e-07 29.9 0.2 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.11 EXF73146.1 - 0.0058 16.2 0.0 0.0089 15.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_transf_4 PF13439.1 EXF73146.1 - 0.076 12.7 0.3 0.9 9.2 0.2 2.1 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Trp_DMAT PF11991.3 EXF73147.1 - 4.9e-77 259.5 0.0 5.6e-77 259.3 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase DUF4351 PF14261.1 EXF73147.1 - 0.14 12.0 0.5 0.26 11.1 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4351) p450 PF00067.17 EXF73148.1 - 8.4e-67 225.6 0.0 9.8e-67 225.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.3 EXF73149.1 - 0.064 11.8 0.0 0.096 11.2 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF423 PF04241.10 EXF73150.1 - 1.7e-22 79.1 1.7 3.4e-22 78.1 1.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Bax1-I PF01027.15 EXF73150.1 - 0.0041 16.7 1.0 0.005 16.4 0.7 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF1469 PF07332.6 EXF73150.1 - 0.043 13.5 4.4 4.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Yip1 PF04893.12 EXF73150.1 - 0.9 9.0 7.8 6.6 6.2 5.4 1.9 1 1 0 1 1 1 0 Yip1 domain ADH_N PF08240.7 EXF73151.1 - 5.2e-19 68.0 0.1 1.3e-18 66.7 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF73151.1 - 2.8e-08 33.3 0.5 1.7e-06 27.6 0.1 2.6 2 1 0 2 2 2 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 EXF73151.1 - 0.0002 19.9 0.2 0.00028 19.4 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein ADH_zinc_N_2 PF13602.1 EXF73151.1 - 0.0019 19.0 0.0 0.0035 18.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GFA PF04828.9 EXF73153.1 - 1.3e-23 82.7 1.0 2e-23 82.1 0.7 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Metallothio_11 PF02066.10 EXF73153.1 - 0.097 12.5 6.0 3.6 7.5 2.1 2.4 2 0 0 2 2 2 0 Metallothionein family 11 Nudix_N_2 PF14803.1 EXF73153.1 - 0.7 9.6 0.1 0.7 9.6 0.0 2.9 3 0 0 3 3 3 0 Nudix N-terminal ABC_tran PF00005.22 EXF73154.1 - 7.1e-33 113.8 0.0 1.5e-32 112.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EXF73154.1 - 3e-19 69.5 9.3 3.7e-19 69.1 2.4 2.3 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 EXF73154.1 - 4.9e-05 22.6 0.0 0.00018 20.7 0.0 1.7 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain PAM2 PF07145.10 EXF73154.1 - 0.00028 20.1 0.3 0.0098 15.3 0.1 2.5 2 0 0 2 2 2 1 Ataxin-2 C-terminal region AAA_21 PF13304.1 EXF73154.1 - 0.0003 20.8 0.0 0.024 14.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EXF73154.1 - 0.0027 16.9 0.0 0.0054 15.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 T2SE PF00437.15 EXF73154.1 - 0.0069 15.3 0.0 0.17 10.7 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_17 PF13207.1 EXF73154.1 - 0.014 16.2 0.0 0.044 14.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EXF73154.1 - 0.018 14.6 0.1 0.063 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EXF73154.1 - 0.024 14.1 0.4 0.072 12.6 0.3 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EXF73154.1 - 0.046 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin TPR_11 PF13414.1 EXF73155.1 - 2.4e-18 65.5 8.1 2.3e-15 55.9 3.1 2.5 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EXF73155.1 - 1.1e-15 56.4 4.8 6.4e-07 28.7 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EXF73155.1 - 1.1e-13 49.9 7.4 6.6e-06 25.6 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EXF73155.1 - 9.5e-08 32.5 18.7 0.00051 20.6 2.6 2.5 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EXF73155.1 - 8.3e-07 28.7 5.6 0.0014 18.6 0.2 3.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EXF73155.1 - 6.6e-06 25.9 7.5 0.002 18.0 0.4 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EXF73155.1 - 8.4e-05 22.8 15.1 0.006 17.1 0.5 4.1 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EXF73155.1 - 8.8e-05 22.0 0.3 0.29 11.0 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EXF73155.1 - 0.00025 21.3 0.7 0.00025 21.3 0.5 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EXF73155.1 - 0.001 18.8 2.7 0.0043 16.8 0.3 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EXF73155.1 - 0.002 17.7 5.5 1.2 9.1 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat BTAD PF03704.12 EXF73155.1 - 0.0036 17.6 7.2 1.1 9.4 5.0 2.7 1 1 0 1 1 1 1 Bacterial transcriptional activator domain XPC-binding PF09280.6 EXF73155.1 - 0.052 13.0 5.6 0.029 13.8 1.8 2.0 2 0 0 2 2 2 0 XPC-binding domain TPR_10 PF13374.1 EXF73155.1 - 0.25 11.3 2.5 16 5.6 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_3 PF01596.12 EXF73156.1 - 9.7e-34 116.2 0.0 1.4e-33 115.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EXF73156.1 - 6.4e-11 43.0 0.0 1.5e-10 41.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EXF73156.1 - 2.1e-10 40.4 0.0 2.8e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EXF73156.1 - 3.1e-10 39.8 0.0 4.4e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF73156.1 - 5.3e-07 30.2 0.0 7.9e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF73156.1 - 0.00054 20.2 0.0 0.00088 19.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF73156.1 - 0.00072 19.5 0.0 0.0013 18.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF73156.1 - 0.0096 16.3 0.0 0.094 13.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF73156.1 - 0.013 14.5 0.0 0.021 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_12 PF08242.7 EXF73156.1 - 0.015 15.7 0.0 0.035 14.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EXF73156.1 - 0.057 12.7 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.1 EXF73156.1 - 0.094 12.4 0.0 13 5.4 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain Fibrillarin PF01269.12 EXF73156.1 - 0.12 11.2 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin Methyltransf_23 PF13489.1 EXF73160.1 - 8.6e-24 84.0 0.0 1.3e-23 83.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF73160.1 - 1.5e-09 37.6 0.0 2.4e-08 33.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF73160.1 - 4.7e-09 36.8 0.0 5.6e-08 33.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF73160.1 - 7.7e-09 35.9 0.0 1.2e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF73160.1 - 1.6e-07 31.7 0.0 1.7e-06 28.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF73160.1 - 5.1e-06 26.7 0.0 1.1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EXF73160.1 - 0.011 15.7 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 EXF73160.1 - 0.017 14.5 0.0 0.033 13.5 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 EXF73160.1 - 0.028 13.9 0.0 0.048 13.1 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EXF73160.1 - 0.047 13.7 0.0 0.13 12.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EXF73160.1 - 0.055 12.5 0.0 0.083 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EXF73160.1 - 0.081 11.9 0.0 0.2 10.7 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase Maf1 PF09174.5 EXF73161.1 - 9.9e-52 175.3 0.0 1.5e-51 174.7 0.0 1.3 1 0 0 1 1 1 1 Maf1 regulator Clat_adaptor_s PF01217.15 EXF73161.1 - 1.7e-50 170.4 1.5 2.7e-50 169.7 1.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Med15_fungi PF05397.7 EXF73161.1 - 0.04 13.8 0.0 12 5.9 0.0 3.1 3 0 0 3 3 3 0 Mediator complex subunit 15 Aldo_ket_red PF00248.16 EXF73162.1 - 5.3e-10 38.5 0.0 7.7e-10 38.0 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ECR1_N PF14382.1 EXF73163.1 - 7.2e-13 47.6 0.1 1.5e-12 46.5 0.1 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.4 EXF73163.1 - 0.0006 19.7 0.5 0.0054 16.6 0.2 2.6 2 1 0 2 2 2 1 Exosome component EXOSC1/CSL4 S1 PF00575.18 EXF73163.1 - 0.084 12.9 1.6 9.8 6.3 0.0 4.0 5 0 0 5 5 5 0 S1 RNA binding domain DUF4536 PF15055.1 EXF73164.1 - 0.001 19.0 3.8 0.002 18.1 2.6 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4536) Adap_comp_sub PF00928.16 EXF73165.1 - 2.4e-60 203.8 0.0 1.6e-59 201.1 0.0 1.9 1 1 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EXF73165.1 - 2.4e-05 24.0 0.0 3.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Acyl_transf_1 PF00698.16 EXF73166.1 - 2.3e-19 69.9 0.0 7.8e-14 51.7 0.0 2.2 2 0 0 2 2 2 2 Acyl transferase domain Sedlin_N PF04628.8 EXF73167.1 - 2e-20 73.0 0.0 2.5e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Cache_3 PF14827.1 EXF73167.1 - 0.03 14.2 0.3 0.06 13.2 0.1 1.6 2 0 0 2 2 2 0 Sensory domain of two-component sensor kinase Sybindin PF04099.7 EXF73167.1 - 0.16 11.6 0.0 6.2 6.5 0.0 2.2 2 0 0 2 2 2 0 Sybindin-like family AFG1_ATPase PF03969.11 EXF73168.1 - 1.6e-54 185.1 0.2 6.7e-27 94.2 0.0 4.6 4 1 1 5 5 5 4 AFG1-like ATPase AAA_16 PF13191.1 EXF73168.1 - 0.00013 22.0 1.9 0.0057 16.6 0.2 3.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EXF73168.1 - 0.00021 21.0 0.0 0.00051 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EXF73168.1 - 0.0028 17.7 0.0 0.011 15.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EXF73168.1 - 0.0096 16.1 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 EXF73168.1 - 0.0099 15.5 0.0 0.18 11.3 0.0 2.3 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_14 PF13173.1 EXF73168.1 - 0.016 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 EXF73168.1 - 0.088 11.7 0.0 0.14 11.0 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain AAA_29 PF13555.1 EXF73168.1 - 0.11 12.0 0.0 0.29 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EXF73168.1 - 0.13 12.5 0.1 3.4 7.9 0.0 2.3 1 1 1 2 2 2 0 ABC transporter Nucleoporin_C PF03177.9 EXF73169.1 - 5e-82 276.2 19.3 7.1e-82 275.7 13.4 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EXF73169.1 - 2.6e-79 266.9 0.0 3.7e-79 266.4 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like Pkinase PF00069.20 EXF73170.1 - 1e-35 123.1 0.0 1.3e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF73170.1 - 2.4e-14 53.0 0.0 3e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EXF73170.1 - 0.015 15.0 0.0 0.48 10.1 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Fungal_trans PF04082.13 EXF73171.1 - 3e-13 49.2 0.0 5.8e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF73171.1 - 1.6e-05 24.7 7.0 3e-05 23.8 4.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Hexapep_2 PF14602.1 EXF73172.1 - 2.8e-14 52.3 25.1 2.6e-09 36.4 2.6 3.1 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Mac PF12464.3 EXF73172.1 - 1.5e-12 47.2 0.0 4.2e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 EXF73172.1 - 5.2e-12 44.7 21.4 3.1e-09 35.9 2.1 3.8 4 1 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Zn_clus PF00172.13 EXF73172.1 - 1e-09 38.1 8.6 2e-09 37.2 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain APG5 PF04106.7 EXF73173.1 - 1.9e-40 138.4 0.0 2.2e-39 134.9 0.0 2.2 1 1 0 1 1 1 1 Autophagy protein Apg5 DEC-1_N PF04625.8 EXF73173.1 - 9.3 4.8 11.3 14 4.2 7.8 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region zf-HYPF PF07503.7 EXF73174.1 - 0.0048 16.2 1.8 0.016 14.5 1.2 1.9 1 0 0 1 1 1 1 HypF finger Methyltransf_23 PF13489.1 EXF73175.1 - 7.6e-13 48.4 0.0 5.2e-12 45.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF73175.1 - 4.7e-08 33.4 0.0 1.7e-07 31.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF73175.1 - 9.1e-05 22.0 0.0 0.00015 21.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF73175.1 - 0.001 19.0 0.0 0.0022 18.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF73175.1 - 0.0022 18.5 0.0 0.0095 16.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF73175.1 - 0.0035 17.7 0.0 0.0085 16.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF73175.1 - 0.0056 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ldh_2 PF02615.9 EXF73177.1 - 7.5e-101 337.2 0.0 8.7e-101 336.9 0.0 1.0 1 0 0 1 1 1 1 Malate/L-lactate dehydrogenase Fungal_trans PF04082.13 EXF73178.1 - 2.3e-20 72.5 0.5 1.3e-18 66.7 0.3 2.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF73178.1 - 5.6e-10 38.9 8.9 1.1e-09 38.0 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MHC_II_alpha PF00993.15 EXF73178.1 - 0.053 13.0 0.1 0.14 11.7 0.1 1.7 1 0 0 1 1 1 0 Class II histocompatibility antigen, alpha domain HypA PF01155.14 EXF73178.1 - 0.96 9.1 3.5 1.3 8.6 1.8 1.6 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family ILVD_EDD PF00920.16 EXF73179.1 - 3.7e-158 527.2 0.6 4.2e-158 527.0 0.4 1.0 1 0 0 1 1 1 1 Dehydratase family adh_short_C2 PF13561.1 EXF73180.1 - 1.8e-32 113.0 0.1 2.1e-32 112.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EXF73180.1 - 1e-17 64.5 2.8 1.4e-17 64.0 2.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF73180.1 - 0.00012 21.7 0.5 0.0002 21.0 0.3 1.3 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.14 EXF73180.1 - 0.11 11.6 0.3 0.19 10.8 0.2 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_1 PF07690.11 EXF73181.1 - 3.3e-24 85.2 22.4 3.3e-24 85.2 15.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4538 PF15061.1 EXF73181.1 - 1.6 8.0 6.1 10 5.5 0.0 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4538) Glyco_hydro_88 PF07470.8 EXF73182.1 - 8.3e-11 41.5 0.3 2.2e-10 40.0 0.2 1.7 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 DUF982 PF06169.7 EXF73182.1 - 0.061 13.0 2.2 0.074 12.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF982) DUF4243 PF14027.1 EXF73182.1 - 0.086 12.2 1.9 0.095 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4243) Fungal_trans PF04082.13 EXF73183.1 - 3.4e-23 81.8 0.1 7.6e-23 80.6 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF73183.1 - 0.0015 18.3 14.0 0.0028 17.5 9.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF885 PF05960.6 EXF73184.1 - 4.6e-43 148.2 0.0 6e-43 147.8 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) DUF4253 PF14062.1 EXF73184.1 - 0.0041 16.7 0.0 0.0084 15.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4253) DUF4286 PF14114.1 EXF73184.1 - 0.027 14.7 0.2 0.073 13.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4286) Arylsulfotran_2 PF14269.1 EXF73185.1 - 3.1e-97 325.3 0.1 4.6e-97 324.7 0.1 1.3 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EXF73185.1 - 3.9e-09 35.5 0.1 2e-08 33.1 0.0 1.9 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) BTK PF00779.14 EXF73186.1 - 1.9 8.1 10.6 0.25 10.9 1.0 2.6 2 0 0 2 2 2 0 BTK motif RicinB_lectin_2 PF14200.1 EXF73188.1 - 0.00011 22.5 0.0 0.0056 17.0 0.1 2.2 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like Acetyltransf_1 PF00583.19 EXF73189.1 - 2.2e-14 53.2 0.0 3.4e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EXF73189.1 - 8e-09 35.6 0.0 1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EXF73189.1 - 1.6e-08 34.5 0.0 2.6e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EXF73189.1 - 0.0012 19.0 0.0 0.0016 18.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EXF73189.1 - 0.0029 17.3 0.0 0.0047 16.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EXF73189.1 - 0.011 15.5 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 EXF73189.1 - 0.015 15.2 0.0 0.018 15.0 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EXF73189.1 - 0.029 14.2 0.0 0.051 13.4 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 EXF73189.1 - 0.048 12.8 0.0 0.063 12.5 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_8 PF13523.1 EXF73189.1 - 0.066 13.0 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Tim17 PF02466.14 EXF73190.1 - 2.6e-21 75.9 6.0 3.8e-19 68.9 4.1 2.0 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Asparaginase_2 PF01112.13 EXF73191.1 - 1.5e-38 132.3 9.2 4.3e-21 74.9 2.0 3.9 4 1 0 4 4 4 3 Asparaginase FAR1 PF03101.10 EXF73192.1 - 2.6e-05 24.6 0.0 6.6e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 FAR1 DNA-binding domain Phosphodiest PF01663.17 EXF73192.1 - 0.00078 18.8 0.0 0.0024 17.2 0.0 1.8 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase MEDS PF14417.1 EXF73192.1 - 0.063 12.3 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain DUF4200 PF13863.1 EXF73192.1 - 0.19 11.7 9.1 0.37 10.7 6.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF4071 PF13281.1 EXF73192.1 - 2.4 6.9 4.3 0.42 9.4 0.4 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4071) DHC_N1 PF08385.7 EXF73193.1 - 1.1e-190 634.9 6.0 1.1e-190 634.9 4.1 4.8 5 1 0 5 5 4 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EXF73193.1 - 1.1e-129 432.5 7.7 1.1e-129 432.5 5.4 5.7 6 1 0 7 7 7 1 Dynein heavy chain, N-terminal region 2 Dynein_heavy PF03028.10 EXF73193.1 - 1.1e-104 351.0 0.0 2.5e-104 349.8 0.0 1.5 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor AAA_6 PF12774.2 EXF73193.1 - 2.9e-77 259.3 0.0 6.9e-77 258.0 0.0 1.6 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 EXF73193.1 - 1.6e-41 141.6 1.1 3.9e-41 140.3 0.1 2.2 2 0 0 2 2 2 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 EXF73193.1 - 1.5e-40 138.9 0.1 3.1e-39 134.5 0.1 2.7 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 EXF73193.1 - 3.5e-37 127.9 7.4 3.5e-37 127.9 5.1 1.9 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EXF73193.1 - 1.6e-33 115.3 0.1 5.9e-12 45.4 0.0 6.1 5 1 0 5 5 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EXF73193.1 - 2e-21 76.3 0.0 1.2e-19 70.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 EXF73193.1 - 5.4e-15 55.7 0.0 0.017 15.2 0.0 6.1 4 1 0 4 4 4 4 AAA domain AAA PF00004.24 EXF73193.1 - 6.4e-14 52.2 0.1 0.0017 18.5 0.0 5.3 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EXF73193.1 - 1.4e-09 38.7 0.0 0.03 15.1 0.0 6.0 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.1 EXF73193.1 - 1.4e-08 34.7 0.1 0.34 10.7 0.0 5.0 4 0 0 4 4 4 2 AAA domain AAA_18 PF13238.1 EXF73193.1 - 5.5e-08 33.1 0.1 0.04 14.2 0.0 5.5 4 0 0 4 4 4 1 AAA domain AAA_16 PF13191.1 EXF73193.1 - 8.9e-07 29.0 16.7 0.21 11.5 0.0 9.0 7 2 1 9 9 9 2 AAA ATPase domain T2SE PF00437.15 EXF73193.1 - 5.9e-06 25.3 0.0 0.045 12.6 0.0 3.5 4 0 0 4 4 4 2 Type II/IV secretion system protein AAA_29 PF13555.1 EXF73193.1 - 1.2e-05 24.7 0.9 1.4 8.4 0.1 4.0 4 0 0 4 4 4 2 P-loop containing region of AAA domain AAA_19 PF13245.1 EXF73193.1 - 2.4e-05 23.9 0.1 0.9 9.3 0.0 4.5 4 0 0 4 4 4 1 Part of AAA domain Mg_chelatase PF01078.16 EXF73193.1 - 0.00024 20.3 0.9 0.51 9.4 0.0 3.7 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EXF73193.1 - 0.001 18.5 1.3 0.32 10.3 0.0 4.2 4 0 0 4 4 4 1 IstB-like ATP binding protein ABC_tran PF00005.22 EXF73193.1 - 0.0014 18.9 1.7 5.1 7.3 0.0 4.9 4 0 0 4 4 3 1 ABC transporter BRE1 PF08647.6 EXF73193.1 - 0.0016 18.3 2.5 0.0016 18.3 1.7 4.7 4 0 0 4 4 3 1 BRE1 E3 ubiquitin ligase AAA_25 PF13481.1 EXF73193.1 - 0.004 16.5 0.7 0.31 10.4 0.0 3.7 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.17 EXF73193.1 - 0.0069 16.5 0.1 23 5.1 0.0 4.6 4 0 0 4 4 4 0 RNA helicase DUF1774 PF08611.5 EXF73194.1 - 3.9e-32 110.2 1.4 3.9e-32 110.2 1.0 2.5 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1774) ACPS PF01648.15 EXF73194.1 - 1.2e-08 34.7 2.0 1.4e-07 31.3 1.4 2.4 1 1 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Clr5 PF14420.1 EXF73195.1 - 6.9e-06 25.8 0.1 1.7e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Clr5 domain F-box PF00646.28 EXF73196.1 - 0.018 14.6 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 F-box domain Glutaredoxin PF00462.19 EXF73197.1 - 1.5e-13 50.5 0.0 5.4e-13 48.7 0.0 2.0 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 EXF73197.1 - 0.094 12.9 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain FAM176 PF14851.1 EXF73197.1 - 2.5 7.7 4.8 0.51 10.0 0.6 1.8 2 0 0 2 2 2 0 FAM176 family DUF1804 PF08822.6 EXF73198.1 - 0.029 14.1 1.1 0.039 13.6 0.2 1.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1804) GFA PF04828.9 EXF73199.1 - 3.6e-11 42.8 0.1 8.4e-07 28.8 0.1 2.5 2 0 0 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme DUF3485 PF11984.3 EXF73199.1 - 0.04 12.9 2.1 0.07 12.1 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3485) APC_CDC26 PF10471.4 EXF73199.1 - 2.9 8.6 8.0 9.1 7.0 1.1 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Glyco_hydro_53 PF07745.8 EXF73200.1 - 5e-107 357.5 0.2 5.7e-107 357.3 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 Glyco_hydro_cc PF11790.3 EXF73200.1 - 0.00086 18.7 0.4 0.0032 16.9 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase catalytic core Zn_clus PF00172.13 EXF73201.1 - 8.9e-09 35.1 9.3 1.4e-08 34.4 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF73201.1 - 0.013 14.1 0.2 0.019 13.6 0.2 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain DUF3638 PF12340.3 EXF73202.1 - 8.2e-92 306.3 0.1 1.5e-91 305.4 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EXF73202.1 - 3.1e-16 58.1 0.2 6.5e-16 57.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) NmrA PF05368.8 EXF73203.1 - 3.3e-34 118.1 0.2 5.5e-34 117.4 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF73203.1 - 7.1e-12 45.7 0.6 1.6e-11 44.5 0.4 1.7 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EXF73203.1 - 0.00091 18.0 0.1 0.0014 17.3 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family SMC_N PF02463.14 EXF73204.1 - 8.5e-75 250.7 18.9 4.3e-74 248.4 13.1 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EXF73204.1 - 1.9e-26 92.3 0.2 7.2e-26 90.5 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EXF73204.1 - 5.8e-12 46.1 7.8 2e-05 24.7 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EXF73204.1 - 0.00015 21.1 0.0 0.00032 20.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Filament PF00038.16 EXF73204.1 - 0.001 18.6 43.2 0.001 18.6 29.9 4.6 3 1 1 4 4 4 1 Intermediate filament protein TMF_DNA_bd PF12329.3 EXF73204.1 - 0.0052 16.5 6.6 0.0052 16.5 4.6 10.3 7 3 4 11 11 11 2 TATA element modulatory factor 1 DNA binding IncA PF04156.9 EXF73204.1 - 0.0055 16.3 17.6 0.0055 16.3 12.2 7.6 3 2 5 8 8 8 4 IncA protein Spc7 PF08317.6 EXF73204.1 - 0.11 11.1 107.3 0.0074 14.9 16.8 6.3 3 2 3 6 6 6 0 Spc7 kinetochore protein ABC_tran PF00005.22 EXF73204.1 - 0.9 9.8 0.0 0.9 9.8 0.0 7.0 5 2 0 5 5 5 0 ABC transporter Reo_sigmaC PF04582.7 EXF73204.1 - 3.2 6.8 28.4 0.12 11.5 2.2 5.0 3 2 1 5 5 5 0 Reovirus sigma C capsid protein ELYS PF13934.1 EXF73205.1 - 2.1e-64 217.3 0.7 2.5e-64 217.1 0.5 1.0 1 0 0 1 1 1 1 Nuclear pore complex assembly Fungal_trans PF04082.13 EXF73206.1 - 0.0039 16.0 0.0 0.0067 15.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF73206.1 - 0.054 13.4 4.3 0.13 12.2 3.0 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2697 PF10906.3 EXF73207.1 - 0.016 15.1 0.0 0.024 14.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2697) Cellulase PF00150.13 EXF73208.1 - 3.3e-27 95.4 3.3 5.5e-27 94.6 2.3 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_X2 PF03442.9 EXF73208.1 - 2.3e-22 78.5 5.5 6.3e-22 77.2 1.8 3.1 4 0 0 4 4 4 1 Carbohydrate binding domain X2 CBM_1 PF00734.13 EXF73208.1 - 3.4e-12 45.7 13.5 7.7e-12 44.6 9.3 1.7 1 0 0 1 1 1 1 Fungal cellulose binding domain FAD_binding_4 PF01565.18 EXF73209.1 - 3.5e-18 65.4 4.7 1.1e-16 60.5 3.2 2.3 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF73209.1 - 1.9e-11 43.6 0.0 4.1e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like HET PF06985.6 EXF73210.1 - 6.8e-23 81.3 0.7 1.2e-22 80.5 0.5 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ACT_3 PF10000.4 EXF73211.1 - 7.5e-22 76.8 0.1 1.6e-21 75.8 0.0 1.5 2 0 0 2 2 2 1 ACT domain ACT_7 PF13840.1 EXF73211.1 - 5e-09 35.5 0.0 8.5e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 ACT domain AAA_13 PF13166.1 EXF73213.1 - 8.1e-05 21.2 6.8 0.016 13.6 0.9 3.1 3 0 0 3 3 3 1 AAA domain Reo_sigmaC PF04582.7 EXF73213.1 - 0.0011 18.2 6.8 0.29 10.2 0.0 3.3 3 1 0 3 3 3 2 Reovirus sigma C capsid protein Spc7 PF08317.6 EXF73213.1 - 0.0016 17.1 22.6 0.21 10.2 0.6 4.2 3 1 1 4 4 4 2 Spc7 kinetochore protein Phage_GP20 PF06810.6 EXF73213.1 - 0.0048 16.3 3.4 0.0048 16.3 2.3 3.9 3 1 0 4 4 4 1 Phage minor structural protein GP20 ATG16 PF08614.6 EXF73213.1 - 0.014 15.2 26.6 0.28 10.9 0.0 4.5 3 1 1 4 4 4 0 Autophagy protein 16 (ATG16) IncA PF04156.9 EXF73213.1 - 0.078 12.5 22.0 3.4 7.2 0.6 4.4 3 1 1 4 4 4 0 IncA protein TMF_DNA_bd PF12329.3 EXF73213.1 - 0.12 12.1 0.1 0.12 12.1 0.1 7.0 6 2 1 7 7 7 0 TATA element modulatory factor 1 DNA binding Plasmid_parti PF01672.11 EXF73213.1 - 0.26 11.7 0.4 0.59 10.6 0.3 1.5 1 0 0 1 1 1 0 Putative plasmid partition protein Fib_alpha PF08702.5 EXF73213.1 - 0.4 10.7 14.3 10 6.2 2.7 4.7 4 2 1 5 5 5 0 Fibrinogen alpha/beta chain family GAS PF13851.1 EXF73213.1 - 0.53 9.4 23.0 0.78 8.8 2.3 4.3 3 1 2 5 5 5 0 Growth-arrest specific micro-tubule binding BLOC1_2 PF10046.4 EXF73213.1 - 0.69 10.0 10.3 7.2 6.8 1.1 4.0 3 2 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TBPIP PF07106.8 EXF73213.1 - 0.77 9.2 16.5 1.6 8.2 2.3 4.7 4 2 1 5 5 5 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) OmpH PF03938.9 EXF73213.1 - 2.6 7.9 12.8 1.6 8.6 3.0 2.8 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) TMF_TATA_bd PF12325.3 EXF73213.1 - 3.6 7.3 27.1 0.3 10.8 1.5 4.9 4 2 1 5 5 5 0 TATA element modulatory factor 1 TATA binding Sec2p PF06428.6 EXF73213.1 - 4.5 7.1 19.0 4 7.3 0.5 4.9 3 2 1 5 5 5 0 GDP/GTP exchange factor Sec2p Filament PF00038.16 EXF73213.1 - 4.9 6.5 29.0 22 4.3 10.4 4.6 3 2 1 4 4 4 0 Intermediate filament protein Tox-REase-2 PF15646.1 EXF73213.1 - 7.6 6.4 7.4 4 7.3 0.1 3.0 2 1 2 4 4 4 0 Restriction endonuclease fold toxin 2 OTT_1508_deam PF14441.1 EXF73214.1 - 2.9e-13 49.8 0.0 6.4e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 OTT_1508-like deaminase Pyr_redox_3 PF13738.1 EXF73215.1 - 5.4e-28 98.4 0.0 6.1e-27 95.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EXF73215.1 - 2.8e-16 58.8 0.0 9.2e-16 57.1 0.0 1.7 1 1 1 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EXF73215.1 - 1e-11 44.3 0.0 7.7e-11 41.4 0.0 2.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EXF73215.1 - 4.5e-08 33.0 0.1 1.2e-06 28.4 0.1 3.0 2 1 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EXF73215.1 - 8.3e-07 29.0 0.0 1.7e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF73215.1 - 3.5e-05 22.4 0.4 0.099 11.0 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 EXF73215.1 - 0.0001 22.2 0.0 0.00023 21.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EXF73215.1 - 0.00082 18.5 0.1 0.0018 17.4 0.0 1.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EXF73215.1 - 0.003 16.6 0.1 0.63 9.0 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EXF73215.1 - 0.039 12.8 0.2 0.38 9.6 0.3 2.4 2 1 0 2 2 2 0 Lycopene cyclase protein Tyrosinase PF00264.15 EXF73216.1 - 7.1e-36 124.4 0.0 9.9e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF3188 PF11384.3 EXF73217.1 - 0.041 13.4 3.4 1 8.9 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3188) Tyrosinase PF00264.15 EXF73218.1 - 2.4e-36 125.9 0.6 3.2e-36 125.5 0.4 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase HMG_box PF00505.14 EXF73218.1 - 0.05 13.8 0.0 0.087 13.1 0.0 1.3 1 0 0 1 1 1 0 HMG (high mobility group) box CorA PF01544.13 EXF73219.1 - 4.3e-07 29.2 0.0 1.4e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF3425 PF11905.3 EXF73220.1 - 4.3e-29 101.1 0.3 1.2e-28 99.7 0.2 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF3425) adh_short PF00106.20 EXF73221.1 - 2.7e-17 63.1 0.0 4.3e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF73221.1 - 4.7e-09 36.1 0.0 8.2e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF73221.1 - 4.4e-07 29.9 0.0 7.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EXF73221.1 - 0.0012 18.3 0.0 0.0024 17.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF73221.1 - 0.0071 16.3 0.0 0.0095 15.9 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EXF73222.1 - 4.6e-27 94.9 0.8 6.6e-27 94.4 0.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF73222.1 - 1.9e-17 63.8 0.0 2.5e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF73222.1 - 3.1e-07 30.2 0.6 4.9e-07 29.5 0.4 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF73222.1 - 6e-05 22.5 0.4 0.0001 21.8 0.3 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF73222.1 - 0.001 19.1 0.1 0.0017 18.3 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EXF73222.1 - 0.0069 16.3 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.14 EXF73222.1 - 0.025 13.7 0.0 0.049 12.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EXF73222.1 - 0.039 13.4 0.4 0.087 12.3 0.3 1.7 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.12 EXF73222.1 - 0.057 12.2 0.0 0.083 11.7 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DUF1776 PF08643.5 EXF73222.1 - 0.17 10.9 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) MFS_1 PF07690.11 EXF73223.1 - 4.2e-39 134.2 50.3 9.5e-39 133.0 34.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2919 PF11143.3 EXF73223.1 - 0.00098 18.9 1.7 0.064 13.0 0.1 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF2919) DUF4407 PF14362.1 EXF73223.1 - 9.1 5.1 6.6 2.7 6.8 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) ketoacyl-synt PF00109.21 EXF73224.1 - 3e-74 249.7 1.1 4.8e-74 249.0 0.1 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EXF73224.1 - 1.3e-50 172.5 0.3 2.6e-50 171.5 0.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EXF73224.1 - 3e-47 160.6 0.0 7.8e-47 159.2 0.0 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EXF73224.1 - 3.1e-41 141.4 0.1 1.4e-38 132.7 0.1 2.3 1 1 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EXF73224.1 - 3e-37 128.1 0.0 1.1e-36 126.2 0.0 2.2 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EXF73224.1 - 2e-30 105.0 0.1 7.3e-30 103.2 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EXF73224.1 - 1e-17 64.3 0.0 2.8e-17 63.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF73224.1 - 2.9e-10 40.4 0.0 1.8e-09 37.9 0.0 2.5 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF73224.1 - 5.6e-10 39.1 0.0 1.3e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF73224.1 - 1.1e-08 34.7 0.0 4.3e-08 32.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 EXF73224.1 - 2e-08 34.3 0.1 6e-08 32.8 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 EXF73224.1 - 2.2e-08 34.6 0.0 7.6e-08 32.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF73224.1 - 2.2e-07 31.1 0.0 0.0002 21.6 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.18 EXF73224.1 - 4.4e-05 22.5 0.1 0.00011 21.2 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 EXF73224.1 - 0.00029 20.0 0.0 0.00068 18.8 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EXF73224.1 - 0.0036 17.3 0.0 0.025 14.6 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain DUF3639 PF12341.3 EXF73224.1 - 0.023 14.6 0.3 5.2 7.1 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3639) DUF938 PF06080.7 EXF73224.1 - 0.037 13.5 0.0 0.085 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_16 PF10294.4 EXF73224.1 - 0.18 11.2 0.0 0.5 9.8 0.0 1.7 2 0 0 2 2 1 0 Putative methyltransferase p450 PF00067.17 EXF73225.1 - 2e-66 224.4 0.0 2.7e-66 224.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 EXF73226.1 - 3e-11 42.9 0.0 8.4e-11 41.5 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF73226.1 - 3.9e-05 23.3 0.7 9.4e-05 22.1 0.5 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Aldose_epim PF01263.15 EXF73227.1 - 4e-18 65.5 0.1 4.1e-13 49.0 0.0 2.6 2 1 0 2 2 2 2 Aldose 1-epimerase DXP_redisom_C PF08436.7 EXF73227.1 - 0.067 13.0 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal FSH1 PF03959.8 EXF73228.1 - 1.1e-25 90.4 0.0 1.4e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EXF73228.1 - 1e-06 28.8 0.5 4.5e-05 23.4 0.0 1.9 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EXF73228.1 - 0.15 11.5 0.0 0.48 9.8 0.0 1.9 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase Zn_clus PF00172.13 EXF73229.1 - 6.9e-06 25.8 9.2 1.2e-05 25.1 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EXF73230.1 - 9.3e-22 77.2 30.2 3.2e-11 42.5 6.9 2.7 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF1218 PF06749.7 EXF73230.1 - 0.016 15.6 0.6 0.016 15.6 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1218) DUF1510 PF07423.6 EXF73230.1 - 0.086 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Amnionless PF14828.1 EXF73230.1 - 0.12 10.8 0.1 3.6 5.9 0.0 2.1 2 0 0 2 2 2 0 Amnionless DUF204 PF02659.10 EXF73230.1 - 1.7 8.8 10.7 1.9 8.6 0.3 3.5 3 0 0 3 3 3 0 Domain of unknown function DUF NfeD PF01957.13 EXF73230.1 - 5.4 7.1 9.0 9.7 6.3 0.5 3.0 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding Glyco_hydro_31 PF01055.21 EXF73231.1 - 8.1e-83 278.6 0.7 1e-82 278.3 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EXF73231.1 - 8.9e-14 51.1 0.0 8.1e-13 48.0 0.0 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like MSP1b PF03429.8 EXF73232.1 - 0.051 11.4 0.2 0.077 10.8 0.1 1.2 1 0 0 1 1 1 0 Major surface protein 1B CN_hydrolase PF00795.17 EXF73233.1 - 7.4e-09 35.2 0.0 1.2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Peptidase_S10 PF00450.17 EXF73234.1 - 5.5e-103 345.3 3.1 7e-103 344.9 2.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Dynamin_N PF00350.18 EXF73235.1 - 1.5e-30 106.2 0.1 2.4e-30 105.5 0.1 1.3 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EXF73235.1 - 1.7e-12 46.7 0.0 3.8e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 EXF73235.1 - 2e-06 27.7 0.0 1.6e-05 24.8 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_23 PF13476.1 EXF73235.1 - 0.0015 18.8 0.1 0.0059 16.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain FeoB_N PF02421.13 EXF73235.1 - 0.005 16.1 0.0 0.67 9.2 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B GED PF02212.13 EXF73235.1 - 0.0053 16.6 1.1 0.013 15.3 0.3 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain Miro PF08477.8 EXF73235.1 - 0.01 16.3 0.0 0.029 14.8 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_21 PF13304.1 EXF73235.1 - 0.018 15.0 0.0 0.034 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EXF73235.1 - 0.052 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Amidohydro_2 PF04909.9 EXF73235.1 - 0.077 12.5 0.1 0.31 10.5 0.0 2.0 2 0 0 2 2 2 0 Amidohydrolase SMC_N PF02463.14 EXF73235.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Cation_ATPase_C PF00689.16 EXF73236.1 - 6.9e-26 90.8 5.4 1.3e-25 90.0 3.8 1.4 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EXF73236.1 - 2.3e-18 67.4 0.0 3.4e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EXF73236.1 - 2.9e-13 49.5 0.0 6.1e-13 48.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EXF73236.1 - 3.2e-05 24.1 0.0 0.00012 22.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EXF73236.1 - 0.0024 17.4 0.3 0.0049 16.4 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EXF73237.1 - 2.1e-45 154.5 2.2 1.1e-44 152.1 2.6 1.4 2 0 0 2 2 2 1 E1-E2 ATPase DUF2448 PF10476.4 EXF73237.1 - 0.13 11.8 1.5 0.24 10.9 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) DUF843 PF05814.6 EXF73241.1 - 0.054 13.2 1.1 1.2 8.9 0.0 3.0 2 1 1 3 3 3 0 Baculovirus protein of unknown function (DUF843) DUF2975 PF11188.3 EXF73241.1 - 0.077 12.7 6.9 0.39 10.4 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) DUF4064 PF13273.1 EXF73241.1 - 0.12 12.5 4.5 0.4 10.8 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) EphA2_TM PF14575.1 EXF73241.1 - 0.15 12.4 0.7 4.5 7.7 0.0 2.8 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF1761 PF08570.5 EXF73242.1 - 0.00064 19.7 4.7 0.11 12.4 1.3 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1761) DUF1510 PF07423.6 EXF73242.1 - 0.019 14.3 9.7 0.39 10.0 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF4027 PF13219.1 EXF73242.1 - 0.042 13.2 0.3 0.12 11.8 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) DUF3357 PF11837.3 EXF73242.1 - 0.074 12.9 0.4 1.5 8.7 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF3357) EphA2_TM PF14575.1 EXF73242.1 - 0.16 12.4 0.2 37 4.7 0.0 2.9 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain SpoIIIAH PF12685.2 EXF73242.1 - 0.41 10.1 6.3 3.5 7.0 0.0 2.3 2 1 0 2 2 2 0 SpoIIIAH-like protein MU117 PF15474.1 EXF73244.1 - 8.4e-15 55.0 10.1 1.1e-14 54.6 7.0 1.2 1 0 0 1 1 1 1 Meiotically up-regulated gene family Kp4 PF09044.5 EXF73244.1 - 0.001 18.8 6.7 0.0018 18.1 4.7 1.4 1 0 0 1 1 1 1 Kp4 Pkinase PF00069.20 EXF73245.1 - 2.3e-41 141.6 0.0 3.5e-41 141.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF73245.1 - 9.3e-21 74.0 0.0 1.3e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF73245.1 - 5e-05 22.4 0.0 0.0021 17.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EXF73245.1 - 0.01 15.6 0.0 0.092 12.4 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EXF73245.1 - 0.083 12.2 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL SUR7 PF06687.7 EXF73247.1 - 4.1e-13 49.3 3.3 6.5e-13 48.7 2.3 1.2 1 0 0 1 1 1 1 SUR7/PalI family Turandot PF07240.6 EXF73248.1 - 0.081 12.4 0.0 2.1 7.8 0.0 2.9 3 1 1 4 4 4 0 Stress-inducible humoral factor Turandot Glyco_hydro_71 PF03659.9 EXF73250.1 - 2.7e-154 513.3 2.9 2.7e-154 513.3 2.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 PLRV_ORF5 PF01690.12 EXF73250.1 - 0.65 9.0 14.7 1 8.4 10.2 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Acetyltransf_1 PF00583.19 EXF73251.1 - 3.9e-08 33.2 0.0 6.2e-08 32.5 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF73251.1 - 4.8e-05 23.4 0.0 9.2e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EXF73251.1 - 5.9e-05 23.1 0.0 0.0017 18.4 0.0 2.7 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EXF73251.1 - 0.0038 17.0 0.0 0.22 11.3 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EXF73251.1 - 0.027 14.6 0.0 0.6 10.2 0.0 2.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain SNARE_assoc PF09335.6 EXF73252.1 - 0.0027 17.8 0.8 0.32 11.1 0.3 2.3 1 1 1 2 2 2 2 SNARE associated Golgi protein Colicin PF01024.14 EXF73252.1 - 0.21 11.1 0.7 0.41 10.2 0.5 1.6 1 1 0 1 1 1 0 Colicin pore forming domain JAB PF01398.16 EXF73253.1 - 9.3e-15 54.3 0.0 2.3e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EXF73253.1 - 2e-06 27.2 0.0 5.7e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain USP8_dimer PF08969.6 EXF73253.1 - 9.4e-05 22.3 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 USP8 dimerisation domain DUF334 PF03904.8 EXF73253.1 - 0.12 11.6 0.1 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) CDC37_M PF08565.6 EXF73254.1 - 0.011 15.1 0.1 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 Cdc37 Hsp90 binding domain ESCRT-II PF05871.7 EXF73254.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 ESCRT-II complex subunit Prefoldin_2 PF01920.15 EXF73255.1 - 1.1e-19 70.0 13.3 1.5e-19 69.7 9.2 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_3 PF13758.1 EXF73255.1 - 0.0049 16.6 5.1 0.0069 16.1 3.5 1.3 1 0 0 1 1 1 1 Prefoldin subunit PDDEXK_1 PF12705.2 EXF73255.1 - 0.086 12.2 4.1 0.1 11.9 2.9 1.0 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF4201 PF13870.1 EXF73255.1 - 0.11 11.9 12.4 0.24 10.8 0.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) DUF2507 PF10702.4 EXF73255.1 - 0.11 12.1 2.0 0.12 11.9 0.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2507) IncA PF04156.9 EXF73255.1 - 0.22 11.1 14.8 0.88 9.1 10.3 1.8 1 1 0 1 1 1 0 IncA protein MutS_IV PF05190.13 EXF73255.1 - 0.26 11.4 2.8 6.3 7.0 1.7 2.4 1 1 0 1 1 1 0 MutS family domain IV Scaffolding_pro PF11418.3 EXF73255.1 - 0.29 11.4 4.9 2.4 8.5 1.2 2.1 1 1 1 2 2 2 0 Phi29 scaffolding protein TPR_MLP1_2 PF07926.7 EXF73255.1 - 0.47 10.1 14.3 0.29 10.8 3.9 2.2 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CDC37_N PF03234.9 EXF73255.1 - 0.56 10.4 7.1 0.68 10.2 4.9 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding TMPIT PF07851.8 EXF73255.1 - 0.76 8.7 6.1 0.98 8.4 4.2 1.1 1 0 0 1 1 1 0 TMPIT-like protein Prefoldin PF02996.12 EXF73255.1 - 1.6 8.3 12.7 2.4 7.8 0.7 2.8 1 1 2 3 3 3 0 Prefoldin subunit Occludin_ELL PF07303.8 EXF73255.1 - 2.4 8.9 7.2 2.3 9.0 4.0 1.8 1 1 0 1 1 1 0 Occludin homology domain Spc7 PF08317.6 EXF73255.1 - 2.8 6.5 11.7 4.3 5.9 8.1 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Med28 PF11594.3 EXF73255.1 - 3.3 8.0 8.3 41 4.4 5.8 2.0 1 1 0 1 1 1 0 Mediator complex subunit 28 DUF3847 PF12958.2 EXF73255.1 - 4 7.2 10.8 13 5.5 4.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3847) Spc24 PF08286.6 EXF73255.1 - 4.7 6.9 11.9 1.1 8.9 3.9 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 NPV_P10 PF05531.7 EXF73255.1 - 5.7 7.2 6.4 17 5.7 4.5 2.0 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Herpes_BLRF2 PF05812.7 EXF73255.1 - 5.7 6.7 9.8 11 5.9 5.9 2.1 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein DUF904 PF06005.7 EXF73255.1 - 7.8 6.8 12.8 13 6.2 8.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF904) Kinetocho_Slk19 PF12709.2 EXF73255.1 - 8.3 6.5 13.1 10 6.2 3.3 2.9 2 1 1 3 3 3 0 Central kinetochore-associated AAA PF00004.24 EXF73256.1 - 2.4e-42 144.2 0.0 4.4e-42 143.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EXF73256.1 - 1.5e-23 82.4 0.1 7.3e-23 80.2 0.1 2.2 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EXF73256.1 - 1.1e-22 79.7 1.9 3.3e-22 78.1 1.1 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain RuvB_N PF05496.7 EXF73256.1 - 9.6e-07 28.0 0.0 1.5e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EXF73256.1 - 3.4e-06 27.8 0.0 1.8e-05 25.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EXF73256.1 - 9.9e-06 25.0 0.0 1.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EXF73256.1 - 1.3e-05 24.1 0.0 2.7e-05 23.0 0.0 1.5 2 0 0 2 2 2 1 TIP49 C-terminus AAA_22 PF13401.1 EXF73256.1 - 1.8e-05 24.8 0.1 0.0016 18.5 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EXF73256.1 - 3e-05 24.0 0.1 0.0047 16.9 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EXF73256.1 - 4.1e-05 23.3 0.0 0.00023 20.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EXF73256.1 - 5e-05 23.1 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EXF73256.1 - 5.2e-05 23.3 0.0 0.01 16.0 0.0 2.7 2 0 0 2 2 2 1 RNA helicase DUF815 PF05673.8 EXF73256.1 - 0.00029 19.8 0.0 0.0041 16.0 0.0 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EXF73256.1 - 0.00065 19.5 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EXF73256.1 - 0.002 17.5 0.1 0.26 10.6 0.1 2.5 1 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EXF73256.1 - 0.007 16.2 0.0 0.029 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EXF73256.1 - 0.0089 16.3 0.1 0.025 14.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 EXF73256.1 - 0.0094 15.6 0.0 0.6 9.7 0.0 2.4 1 1 1 2 2 2 1 NACHT domain AAA_24 PF13479.1 EXF73256.1 - 0.014 14.9 0.0 0.029 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EXF73256.1 - 0.02 14.0 0.1 0.11 11.5 0.0 2.3 1 1 0 1 1 1 0 Zeta toxin Mg_chelatase PF01078.16 EXF73256.1 - 0.021 14.0 0.0 0.061 12.4 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EXF73256.1 - 0.022 14.4 0.0 0.066 12.9 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_21 PF13304.1 EXF73256.1 - 0.026 14.4 0.1 2.8 7.8 0.0 2.4 1 1 1 2 2 2 0 AAA domain PhoH PF02562.11 EXF73256.1 - 0.031 13.5 0.1 0.083 12.1 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activ_2 PF14532.1 EXF73256.1 - 0.051 13.6 0.0 0.14 12.2 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain Bac_DnaA PF00308.13 EXF73256.1 - 0.061 12.9 0.0 0.17 11.4 0.0 1.7 1 1 0 1 1 1 0 Bacterial dnaA protein Torsin PF06309.6 EXF73256.1 - 0.071 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Torsin ResIII PF04851.10 EXF73256.1 - 0.082 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.12 EXF73256.1 - 0.09 11.6 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 EXF73256.1 - 0.11 12.4 0.0 0.28 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EXF73256.1 - 0.12 11.8 0.0 0.41 10.1 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 EXF73256.1 - 0.12 11.4 0.0 4.7 6.2 0.0 2.2 1 1 1 2 2 2 0 KaiC W2 PF02020.13 EXF73256.1 - 0.15 12.0 1.0 0.38 10.7 0.7 1.6 1 0 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon Nop PF01798.13 EXF73257.1 - 1.9e-57 192.7 0.3 4.2e-57 191.6 0.2 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EXF73257.1 - 8.2e-20 70.3 0.0 1.8e-19 69.2 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EXF73257.1 - 2.2e-19 69.3 0.0 2.2e-19 69.3 0.0 2.4 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.6 EXF73257.1 - 0.00016 21.4 23.0 0.00029 20.5 15.9 1.4 1 0 0 1 1 1 1 DNA-directed RNA polymerase I subunit RPA34.5 Autotransporter PF03797.14 EXF73257.1 - 0.0005 19.4 0.1 0.00077 18.8 0.1 1.2 1 0 0 1 1 1 1 Autotransporter beta-domain TRAM_LAG1_CLN8 PF03798.11 EXF73258.1 - 1.3e-32 112.9 19.5 1.3e-32 112.9 13.5 1.6 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EXF73258.1 - 2.9e-23 81.1 0.0 7.2e-23 79.8 0.0 1.7 1 0 0 1 1 1 1 TRAM1-like protein Sulfate_transp PF00916.15 EXF73258.1 - 0.14 11.1 2.1 0.29 10.1 0.3 1.9 2 0 0 2 2 2 0 Sulfate transporter family Glyco_hydro_18 PF00704.23 EXF73259.1 - 2.2e-91 306.8 0.6 2.5e-91 306.6 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Ribosomal_S27 PF01599.14 EXF73260.1 - 1.8e-28 98.1 1.8 3.9e-28 97.0 1.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.18 EXF73260.1 - 1.7e-19 68.9 0.1 3.7e-19 67.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EXF73260.1 - 1.1e-09 37.8 0.0 2.5e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EXF73260.1 - 0.0073 16.1 0.1 0.0099 15.7 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 EXF73260.1 - 0.026 14.5 0.3 0.037 14.0 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2870) Stig1 PF04885.8 EXF73260.1 - 0.049 13.8 0.2 0.059 13.5 0.2 1.2 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 DUF971 PF06155.7 EXF73260.1 - 0.051 13.9 0.1 0.096 13.1 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF971) Abhydrolase_6 PF12697.2 EXF73261.1 - 1.1e-26 94.1 0.1 1.5e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF73261.1 - 1.9e-18 66.8 0.1 9.5e-17 61.3 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF73261.1 - 6.2e-08 32.5 0.0 1.8e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EXF73261.1 - 0.00029 20.3 0.0 0.00037 19.9 0.0 1.2 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.8 EXF73261.1 - 0.012 15.2 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.15 EXF73261.1 - 0.014 15.6 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain DUF2048 PF09752.4 EXF73261.1 - 0.021 13.6 0.0 0.069 12.0 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Hydrolase_4 PF12146.3 EXF73261.1 - 0.023 14.5 0.2 0.044 13.6 0.1 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Ndr PF03096.9 EXF73261.1 - 0.1 11.0 0.0 0.16 10.3 0.0 1.2 1 0 0 1 1 1 0 Ndr family Ribosomal_S3Ae PF01015.13 EXF73262.1 - 1.2e-82 276.0 5.0 1.4e-82 275.7 3.5 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Syntaxin PF00804.20 EXF73262.1 - 0.054 13.6 0.2 0.26 11.4 0.0 2.1 2 1 1 3 3 3 0 Syntaxin GTP_CH_N PF12471.3 EXF73264.1 - 9.7e-86 286.3 0.0 1.3e-85 285.9 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase N terminal GTP_cyclohydro2 PF00925.15 EXF73264.1 - 1.9e-15 56.4 0.0 3e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II DUF4254 PF14063.1 EXF73264.1 - 0.088 12.4 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) 53-BP1_Tudor PF09038.5 EXF73264.1 - 0.16 11.8 0.0 0.38 10.5 0.0 1.6 2 0 0 2 2 2 0 Tumour suppressor p53-binding protein-1 Tudor Elf1 PF05129.8 EXF73265.1 - 6.8e-28 96.1 0.3 8.7e-28 95.8 0.2 1.1 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like UPRTase PF14681.1 EXF73266.1 - 7.5e-81 270.2 0.0 8.9e-81 270.0 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EXF73266.1 - 0.00022 20.9 0.0 0.00033 20.3 0.0 1.5 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.8 EXF73266.1 - 0.14 11.9 0.2 0.23 11.2 0.1 1.2 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Ras PF00071.17 EXF73267.1 - 3.9e-42 143.4 0.0 6.4e-42 142.7 0.0 1.3 1 0 0 1 1 1 1 Ras family WAPL PF07814.8 EXF73267.1 - 1.9e-13 49.9 0.1 5.7e-10 38.4 0.0 2.1 2 0 0 2 2 2 2 Wings apart-like protein regulation of heterochromatin Miro PF08477.8 EXF73267.1 - 2.2e-10 41.0 0.0 4.8e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EXF73267.1 - 3.2e-05 23.2 0.0 4.8e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EXF73267.1 - 0.00016 21.1 0.0 0.00031 20.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EXF73267.1 - 0.0033 17.3 0.0 0.0079 16.1 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Fun_ATP-synt_8 PF05933.8 EXF73267.1 - 0.4 10.7 0.9 1.4 9.0 0.2 2.0 2 0 0 2 2 2 0 Fungal ATP synthase protein 8 (A6L) Peptidase_C78 PF07910.8 EXF73268.1 - 9.4e-68 227.5 0.0 1.3e-67 227.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C78 zf-Di19 PF05605.7 EXF73268.1 - 0.012 15.6 0.5 0.031 14.3 0.1 1.9 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Hist_deacetyl PF00850.14 EXF73268.1 - 0.012 14.8 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Histone deacetylase domain PRP21_like_P PF12230.3 EXF73268.1 - 0.016 14.7 0.5 0.031 13.7 0.1 1.6 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Ham1p_like PF01725.11 EXF73269.1 - 1.4e-48 164.8 0.0 2.3e-48 164.0 0.0 1.4 1 0 0 1 1 1 1 Ham1 family AAA_18 PF13238.1 EXF73269.1 - 2.2e-28 99.1 0.0 4.6e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EXF73269.1 - 1.7e-15 57.9 0.2 4.5e-15 56.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EXF73269.1 - 1.2e-05 25.1 0.1 0.0035 17.2 0.0 2.4 1 1 0 2 2 2 1 AAA domain AAA PF00004.24 EXF73269.1 - 8.8e-05 22.7 0.0 0.0035 17.5 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EXF73269.1 - 8.8e-05 22.5 0.1 0.00047 20.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain ADK PF00406.17 EXF73269.1 - 0.0003 20.7 0.0 0.0097 15.7 0.0 2.3 2 0 0 2 2 2 1 Adenylate kinase SKI PF01202.17 EXF73269.1 - 0.0013 18.6 0.2 0.02 14.7 0.2 2.1 1 1 0 1 1 1 1 Shikimate kinase AAA_22 PF13401.1 EXF73269.1 - 0.0017 18.4 0.0 0.01 15.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EXF73269.1 - 0.0025 17.5 0.1 0.0053 16.4 0.1 1.5 1 0 0 1 1 1 1 NTPase Thymidylate_kin PF02223.12 EXF73269.1 - 0.0043 16.4 0.2 2.8 7.2 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA_16 PF13191.1 EXF73269.1 - 0.005 16.8 0.0 0.014 15.4 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain KTI12 PF08433.5 EXF73269.1 - 0.007 15.6 0.0 0.019 14.1 0.0 1.7 2 0 0 2 2 2 1 Chromatin associated protein KTI12 RNA_helicase PF00910.17 EXF73269.1 - 0.012 15.8 0.1 0.12 12.5 0.0 2.3 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.13 EXF73269.1 - 0.015 14.8 0.0 0.03 13.8 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase MobB PF03205.9 EXF73269.1 - 0.021 14.5 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_5 PF07728.9 EXF73269.1 - 0.072 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) SRP54 PF00448.17 EXF73269.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 EXF73269.1 - 0.11 11.9 0.0 0.26 10.6 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain ATP_bind_1 PF03029.12 EXF73269.1 - 0.13 11.8 0.1 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 EXF73269.1 - 0.14 12.0 0.0 0.39 10.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain Myosin_head PF00063.16 EXF73270.1 - 7.5e-241 800.9 0.2 7.5e-241 800.9 0.1 1.7 2 0 0 2 2 1 1 Myosin head (motor domain) DIL PF01843.14 EXF73270.1 - 7.8e-35 118.9 3.5 2.5e-34 117.2 2.4 2.0 1 0 0 1 1 1 1 DIL domain IQ PF00612.22 EXF73270.1 - 3.1e-19 66.7 32.3 5.3e-05 22.4 0.2 6.9 6 0 0 6 6 6 5 IQ calmodulin-binding motif Reo_sigmaC PF04582.7 EXF73270.1 - 9.1e-05 21.7 1.3 0.00019 20.7 0.9 1.5 1 0 0 1 1 1 1 Reovirus sigma C capsid protein AAA_22 PF13401.1 EXF73270.1 - 0.00061 19.9 0.0 0.0026 17.8 0.0 2.2 1 0 0 1 1 1 1 AAA domain GAS PF13851.1 EXF73270.1 - 0.0033 16.6 14.9 0.0033 16.6 10.3 2.7 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding AAA_19 PF13245.1 EXF73270.1 - 0.0039 16.9 0.0 0.02 14.6 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain FlaC_arch PF05377.6 EXF73270.1 - 0.0051 16.6 0.1 0.0051 16.6 0.1 4.4 4 1 1 5 5 5 1 Flagella accessory protein C (FlaC) AAA_16 PF13191.1 EXF73270.1 - 0.0098 15.8 1.8 0.043 13.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Myosin_N PF02736.14 EXF73270.1 - 0.025 14.2 2.4 0.075 12.7 1.7 1.9 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Baculo_PEP_C PF04513.7 EXF73270.1 - 0.069 12.9 13.6 0.035 13.9 4.5 2.8 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus APG6 PF04111.7 EXF73270.1 - 2.2 7.2 29.8 0.35 9.8 14.7 2.4 1 1 1 2 2 2 0 Autophagy protein Apg6 CENP-F_leu_zip PF10473.4 EXF73270.1 - 2.8 7.7 30.1 0.98 9.2 3.4 2.7 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 SOBP PF15279.1 EXF73270.1 - 7.6 6.8 5.5 16 5.7 3.8 1.5 1 0 0 1 1 1 0 Sine oculis-binding protein TMF_TATA_bd PF12325.3 EXF73270.1 - 8.8 6.0 26.4 3.5 7.3 3.9 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Toxin_39 PF15500.1 EXF73270.1 - 9.4 6.4 6.9 3 8.0 0.9 2.9 1 1 1 2 2 2 0 Putative RNase-like toxin 2-Hacid_dh_C PF02826.14 EXF73272.1 - 2.2e-53 180.0 0.0 3.7e-53 179.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EXF73272.1 - 4.2e-32 110.3 0.0 2.9e-31 107.6 0.0 2.0 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EXF73272.1 - 2.8e-06 27.2 0.4 7.8e-06 25.8 0.3 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase AdoHcyase_NAD PF00670.16 EXF73272.1 - 0.00061 19.6 0.1 0.0013 18.5 0.1 1.5 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 EXF73272.1 - 0.0051 16.2 0.3 0.031 13.6 0.0 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain 3HCDH_N PF02737.13 EXF73272.1 - 0.019 14.6 2.6 0.91 9.1 0.4 2.7 2 1 1 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ACT PF01842.20 EXF73272.1 - 0.054 13.0 0.3 0.17 11.3 0.0 2.0 2 0 0 2 2 2 0 ACT domain XdhC_C PF13478.1 EXF73272.1 - 0.067 13.5 0.0 0.19 12.0 0.0 1.8 2 0 0 2 2 2 0 XdhC Rossmann domain NAP PF00956.13 EXF73273.1 - 2.3e-88 295.4 10.4 2.3e-88 295.4 7.2 2.0 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) P5-ATPase PF12409.3 EXF73274.1 - 9.8e-37 125.4 0.1 5.1e-36 123.1 0.0 2.2 2 0 0 2 2 2 1 P5-type ATPase cation transporter HAD PF12710.2 EXF73274.1 - 5e-29 101.8 0.0 9.7e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EXF73274.1 - 1e-26 93.3 0.0 2e-26 92.4 0.0 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EXF73274.1 - 2.3e-15 57.5 0.0 7.5e-14 52.6 0.0 2.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EXF73274.1 - 4e-06 26.4 4.1 1.2e-05 24.8 2.8 1.8 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 EXF73274.1 - 0.019 14.8 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EXF73274.1 - 0.036 13.5 0.1 0.26 10.7 0.0 2.3 2 0 0 2 2 2 0 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EXF73274.1 - 0.22 11.0 0.0 1.5 8.3 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase UQ_con PF00179.21 EXF73275.1 - 1.7e-21 76.0 0.0 2.7e-21 75.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EXF73275.1 - 0.054 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.1 EXF73275.1 - 0.065 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B B-block_TFIIIC PF04182.7 EXF73276.1 - 3.3e-13 49.2 0.0 6.9e-13 48.2 0.0 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC zf-TFIIB PF13453.1 EXF73276.1 - 0.055 12.6 0.1 0.12 11.5 0.1 1.5 1 0 0 1 1 1 0 Transcription factor zinc-finger DUF1610 PF07754.6 EXF73276.1 - 0.32 11.1 0.1 0.71 10.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) Connexin PF00029.14 EXF73278.1 - 0.13 12.3 0.1 0.25 11.4 0.1 1.4 1 0 0 1 1 1 0 Connexin Cyanate_lyase PF02560.9 EXF73279.1 - 2.6e-32 110.1 0.0 4e-32 109.5 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain HTH_31 PF13560.1 EXF73279.1 - 7.3e-05 22.8 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_3 PF01381.17 EXF73279.1 - 0.0012 18.6 0.1 0.0019 18.0 0.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix Sigma70_r4_2 PF08281.7 EXF73279.1 - 0.002 17.5 0.0 0.0044 16.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r4 PF04545.11 EXF73279.1 - 0.03 13.6 0.0 0.072 12.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_38 PF13936.1 EXF73279.1 - 0.031 13.8 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3698 PF12479.3 EXF73279.1 - 0.034 14.2 0.0 0.068 13.2 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3698) Ebp2 PF05890.7 EXF73280.1 - 1.9e-87 293.0 16.7 1.9e-87 293.0 11.6 2.7 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 zf-MYND PF01753.13 EXF73281.1 - 1.3e-07 31.3 19.0 1.3e-07 31.3 13.1 2.0 2 0 0 2 2 2 1 MYND finger Sdh_cyt PF01127.17 EXF73283.1 - 0.025 14.4 0.7 0.04 13.7 0.5 1.3 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit PIG-Y PF15159.1 EXF73283.1 - 2.2 8.5 6.8 6.8 6.9 4.7 1.9 1 1 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Cation_efflux PF01545.16 EXF73284.1 - 4.7e-32 111.1 7.6 5.9e-32 110.8 5.3 1.1 1 0 0 1 1 1 1 Cation efflux family Dynamin_N PF00350.18 EXF73285.1 - 1.8e-43 148.2 0.0 3.4e-43 147.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EXF73285.1 - 6.3e-10 38.3 0.4 8.7e-08 31.2 0.0 2.3 2 0 0 2 2 2 2 Dynamin central region Miro PF08477.8 EXF73285.1 - 0.0017 18.8 0.0 0.0041 17.6 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EXF73285.1 - 0.0019 18.1 0.0 0.0071 16.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EXF73285.1 - 0.018 15.0 0.4 0.13 12.1 0.0 2.4 2 1 0 2 2 2 0 AAA ATPase domain Transpep_BrtH PF14399.1 EXF73285.1 - 0.062 12.5 0.2 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase AAA_21 PF13304.1 EXF73285.1 - 0.088 12.7 0.1 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain GATase_4 PF13230.1 EXF73286.1 - 2.1e-17 62.7 0.1 2e-15 56.2 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EXF73286.1 - 6.5e-09 35.8 0.0 1.5e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EXF73286.1 - 1.9e-06 26.8 0.0 0.00014 20.6 0.0 2.2 2 0 0 2 2 2 2 Glutamine amidotransferases class-II PQ-loop PF04193.9 EXF73288.1 - 6.1e-29 99.3 10.1 3e-17 61.9 0.4 3.0 3 0 0 3 3 3 2 PQ loop repeat Mito_carr PF00153.22 EXF73289.1 - 6.3e-74 243.7 0.5 2.1e-25 88.2 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 EXF73289.1 - 2.7e-18 63.7 6.1 4.7e-08 31.7 0.3 5.1 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.1 EXF73289.1 - 2e-16 58.3 5.2 1.7e-07 30.5 0.3 5.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.1 EXF73289.1 - 3.5e-15 55.8 4.8 5.9e-08 32.7 0.6 4.0 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EXF73289.1 - 8.5e-15 53.3 6.1 7.8e-07 28.1 1.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EXF73289.1 - 1.1e-09 37.7 8.0 0.014 14.9 0.0 5.2 5 1 1 6 6 6 5 EF-hand domain pair EF-hand_9 PF14658.1 EXF73289.1 - 0.055 13.3 0.1 9.3 6.2 0.0 3.4 4 0 0 4 4 4 0 EF-hand domain PepX_C PF08530.5 EXF73290.1 - 2.9e-42 145.0 0.5 4.1e-42 144.5 0.3 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.13 EXF73290.1 - 3.8e-40 138.0 0.1 5.5e-40 137.5 0.1 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EXF73290.1 - 5.3e-07 29.7 0.1 9.6e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF73290.1 - 0.00014 21.5 0.0 0.00033 20.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family IN_DBD_C PF00552.16 EXF73290.1 - 0.0025 17.2 0.0 0.0075 15.6 0.0 1.8 1 0 0 1 1 1 1 Integrase DNA binding domain Hydrolase_4 PF12146.3 EXF73290.1 - 0.01 15.6 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Aldedh PF00171.17 EXF73292.1 - 7.3e-13 47.6 0.7 3.4e-06 25.6 0.1 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family LigB PF02900.13 EXF73293.1 - 1.3e-18 66.9 1.0 1.4e-18 66.8 0.1 1.4 2 0 0 2 2 2 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Med5 PF08689.5 EXF73294.1 - 3.2e-244 812.9 0.0 3.8e-244 812.7 0.0 1.0 1 0 0 1 1 1 1 Mediator complex subunit Med5 SSF PF00474.12 EXF73294.1 - 0.033 12.8 0.2 0.06 11.9 0.1 1.3 1 0 0 1 1 1 0 Sodium:solute symporter family Arm PF00514.18 EXF73295.1 - 2.8e-93 302.9 14.9 1.9e-13 49.6 0.1 8.4 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EXF73295.1 - 2.1e-27 95.2 1.5 7.5e-10 38.9 0.0 5.8 1 1 6 7 7 7 6 HEAT repeats IBB PF01749.15 EXF73295.1 - 5.8e-23 80.8 1.4 9.6e-23 80.1 1.0 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT_EZ PF13513.1 EXF73295.1 - 4.5e-22 77.9 11.4 1.1e-09 38.4 0.1 6.3 6 1 1 7 7 7 4 HEAT-like repeat HEAT PF02985.17 EXF73295.1 - 8.8e-21 72.0 1.2 4.3e-06 26.3 0.0 7.1 7 0 0 7 7 7 4 HEAT repeat Arm_2 PF04826.8 EXF73295.1 - 2.9e-10 39.7 0.0 0.0033 16.5 0.0 4.1 2 1 2 4 4 4 3 Armadillo-like Adaptin_N PF01602.15 EXF73295.1 - 1.1e-05 23.9 0.0 0.0011 17.4 0.0 2.9 1 1 0 2 2 2 1 Adaptin N terminal region V-ATPase_H_C PF11698.3 EXF73295.1 - 0.00048 20.0 0.0 1.6 8.6 0.0 4.3 2 1 2 5 5 5 1 V-ATPase subunit H HEAT_PBS PF03130.11 EXF73295.1 - 0.00063 19.9 0.2 1.4 9.6 0.0 4.4 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Proteasom_PSMB PF10508.4 EXF73295.1 - 0.0025 16.1 0.9 0.28 9.3 0.0 3.1 3 1 1 4 4 4 2 Proteasome non-ATPase 26S subunit Glycos_trans_3N PF02885.12 EXF73295.1 - 0.06 12.9 0.0 18 5.0 0.0 3.4 3 0 0 3 3 3 0 Glycosyl transferase family, helical bundle domain POT1 PF02765.12 EXF73296.1 - 2.3e-10 40.5 0.0 4.3e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 STAG PF08514.6 EXF73297.1 - 3e-25 88.2 0.1 1.7e-24 85.8 0.1 2.3 2 0 0 2 2 2 1 STAG domain UreD PF01774.12 EXF73298.1 - 3.6e-55 186.6 0.0 4.3e-55 186.4 0.0 1.1 1 0 0 1 1 1 1 UreD urease accessory protein RNA_pol_Rpc4 PF05132.9 EXF73299.1 - 7.6e-24 84.1 0.0 7.6e-24 84.1 0.0 3.2 4 0 0 4 4 4 1 RNA polymerase III RPC4 FAD_binding_3 PF01494.14 EXF73300.1 - 4.2e-22 78.6 0.1 3.3e-12 46.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EXF73300.1 - 4.6e-13 48.7 0.4 1.9e-06 27.0 0.0 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF73300.1 - 9.5e-06 24.7 0.5 9.3e-05 21.5 0.4 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.9 EXF73300.1 - 3.4e-05 22.4 0.3 0.0012 17.4 0.2 2.5 1 1 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EXF73300.1 - 6.9e-05 21.8 0.5 0.0019 17.1 0.3 2.2 1 1 1 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EXF73300.1 - 0.00012 22.0 0.0 0.00052 19.9 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF73300.1 - 0.0014 18.7 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF73300.1 - 0.0016 18.4 0.1 0.005 16.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EXF73300.1 - 0.003 17.9 0.0 0.81 10.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Adeno_E3B PF03376.9 EXF73301.1 - 1.1 9.1 9.1 1.2 9.1 0.4 2.7 2 0 0 2 2 2 0 Adenovirus E3B protein Abhydrolase_6 PF12697.2 EXF73302.1 - 9.1e-07 28.9 0.2 1.5e-06 28.2 0.2 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EXF73302.1 - 1e-06 28.5 0.8 8.4e-06 25.5 0.6 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF73302.1 - 0.0012 18.5 0.0 0.0025 17.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF73302.1 - 0.046 12.9 0.0 0.2 10.8 0.0 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family MFS_1 PF07690.11 EXF73303.1 - 4.2e-31 107.9 56.9 9.4e-30 103.5 27.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EXF73303.1 - 0.00034 20.3 9.4 0.07 12.9 3.4 3.3 3 0 0 3 3 3 2 MFS_1 like family GTP_EFTU PF00009.22 EXF73304.1 - 2.3e-47 160.8 0.0 3.8e-47 160.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EXF73304.1 - 1.1e-38 131.4 3.6 2.1e-38 130.5 2.5 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EXF73304.1 - 4.4e-17 61.7 0.0 8.9e-17 60.7 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus MIT PF04212.13 EXF73304.1 - 1.4e-11 44.0 1.3 2.9e-11 43.0 0.9 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain MMR_HSR1 PF01926.18 EXF73304.1 - 0.00015 21.6 0.0 0.00045 20.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase EFG_II PF14492.1 EXF73304.1 - 0.00016 21.4 0.0 0.00045 20.0 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II Ras PF00071.17 EXF73304.1 - 0.00023 20.5 0.0 0.00049 19.5 0.0 1.5 1 0 0 1 1 1 1 Ras family GTP_EFTU_D2 PF03144.20 EXF73304.1 - 0.0019 18.2 0.1 0.0043 17.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.5 EXF73304.1 - 0.1 11.8 0.0 0.27 10.4 0.0 1.7 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Miro PF08477.8 EXF73304.1 - 0.15 12.5 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein His_Phos_1 PF00300.17 EXF73305.1 - 7.3e-18 65.1 0.0 8.9e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) CTNNBL PF08216.6 EXF73306.1 - 3.8e-36 122.9 0.9 2e-35 120.5 0.0 2.6 3 1 1 4 4 4 1 Catenin-beta-like, Arm-motif containing nuclear Arm PF00514.18 EXF73306.1 - 0.0018 18.0 0.0 0.8 9.6 0.0 3.2 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EXF73306.1 - 0.041 14.1 2.2 1.7 8.9 0.1 2.8 2 0 0 2 2 2 0 HEAT repeats DUF1911 PF08929.5 EXF73306.1 - 0.069 13.8 0.2 0.54 10.9 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1911) V-ATPase_G PF03179.10 EXF73307.1 - 1.7e-32 111.8 16.8 2e-32 111.6 11.6 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ATP-synt_B PF00430.13 EXF73307.1 - 0.0025 17.6 9.8 0.0025 17.6 6.8 2.1 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) DUF3552 PF12072.3 EXF73307.1 - 0.0063 15.7 11.5 0.0063 15.7 7.9 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3552) YusW PF14039.1 EXF73307.1 - 0.028 14.7 3.9 0.046 13.9 2.7 1.3 1 0 0 1 1 1 0 YusW-like protein DUF87 PF01935.12 EXF73307.1 - 0.18 11.5 1.7 0.21 11.3 1.2 1.0 1 0 0 1 1 1 0 Domain of unknown function DUF87 RRF PF01765.14 EXF73307.1 - 0.19 11.1 11.2 0.24 10.8 7.8 1.2 1 0 0 1 1 1 0 Ribosome recycling factor Nop25 PF09805.4 EXF73307.1 - 0.2 11.7 16.3 0.26 11.3 11.3 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Vfa1 PF08432.5 EXF73307.1 - 0.42 10.5 12.8 0.52 10.3 8.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2203 PF09969.4 EXF73307.1 - 0.44 10.7 4.1 0.59 10.3 2.8 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) SAPS PF04499.10 EXF73307.1 - 0.59 8.7 7.1 0.65 8.5 5.0 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein HAUS6_N PF14661.1 EXF73307.1 - 0.6 9.4 7.7 0.67 9.2 5.3 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Med8 PF10232.4 EXF73307.1 - 1.1 8.7 6.6 1.3 8.4 4.5 1.1 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 Cauli_AT PF03233.8 EXF73307.1 - 5.4 6.6 8.1 9.5 5.8 3.8 1.9 1 1 1 2 2 2 0 Aphid transmission protein vATP-synt_E PF01991.13 EXF73307.1 - 6.8 5.9 19.8 8.8 5.5 8.7 2.1 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit OmpH PF03938.9 EXF73307.1 - 9.9 6.0 14.7 15 5.4 10.2 1.4 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) RNA_pol_Rpb2_6 PF00562.23 EXF73308.1 - 6.3e-126 420.2 0.2 1.6e-125 418.8 0.1 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EXF73308.1 - 5.4e-57 191.9 0.0 9.5e-57 191.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EXF73308.1 - 1.8e-47 161.2 0.0 3.5e-47 160.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EXF73308.1 - 9.1e-31 105.9 0.0 2.1e-30 104.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EXF73308.1 - 1.1e-23 82.8 0.7 3.1e-23 81.4 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RNA_pol_Rpb2_3 PF04565.11 EXF73308.1 - 8.4e-23 79.9 0.0 1.9e-22 78.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.8 EXF73308.1 - 2.5e-18 65.6 1.4 6.6e-18 64.2 0.9 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 IDO PF01231.13 EXF73309.1 - 1.2e-168 560.9 0.0 1.4e-168 560.7 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase UEV PF05743.8 EXF73310.1 - 3.8e-37 126.6 0.0 3.8e-37 126.6 0.0 1.8 2 0 0 2 2 2 1 UEV domain Vps23_core PF09454.5 EXF73310.1 - 1.5e-21 75.7 0.0 2.6e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Vps23 core domain UQ_con PF00179.21 EXF73310.1 - 0.0053 16.1 0.1 0.01 15.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme STE2 PF02116.10 EXF73312.1 - 0.00013 21.1 0.3 0.00014 21.0 0.2 1.1 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR DUF1996 PF09362.5 EXF73313.1 - 5e-88 294.7 0.0 6.9e-88 294.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 EXF73313.1 - 9.2e-22 76.7 8.9 9.2e-22 76.7 6.2 2.3 2 0 0 2 2 2 1 WSC domain Glyco_hydro_16 PF00722.16 EXF73316.1 - 3.9e-19 68.6 0.8 1.1e-18 67.1 0.6 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 EXF73316.1 - 4.1e-06 25.2 1.9 0.028 12.5 0.6 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF2401 PF10287.4 EXF73316.1 - 0.00054 19.5 0.1 0.00072 19.1 0.1 1.4 1 0 0 1 1 1 1 Putative TOS1-like glycosyl hydrolase (DUF2401) TRAPP PF04051.11 EXF73318.1 - 7.3e-37 126.2 0.0 8.7e-37 125.9 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component DUF4250 PF14056.1 EXF73318.1 - 0.082 12.6 0.1 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4250) WD40 PF00400.27 EXF73319.1 - 1.7e-52 173.5 3.5 1.3e-08 34.4 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EXF73319.1 - 9e-06 24.6 2.2 0.038 12.7 0.2 2.2 1 1 1 2 2 2 2 Nup133 N terminal like SdpI PF13630.1 EXF73320.1 - 0.61 9.8 4.1 0.97 9.1 2.9 1.3 1 0 0 1 1 1 0 SdpI/YhfL protein family DUF726 PF05277.7 EXF73321.1 - 4e-127 423.8 0.3 5.6e-127 423.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Fcf1 PF04900.7 EXF73322.1 - 7.4e-23 80.5 0.2 1.3e-22 79.7 0.2 1.4 1 0 0 1 1 1 1 Fcf1 CDC45 PF02724.9 EXF73322.1 - 0.55 8.2 6.7 0.7 7.8 4.7 1.2 1 0 0 1 1 1 0 CDC45-like protein PP2C PF00481.16 EXF73323.1 - 2.3e-05 23.9 0.1 0.0029 17.0 0.0 2.1 1 1 1 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EXF73323.1 - 0.00063 19.2 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EXF73323.1 - 0.0085 15.8 0.0 0.025 14.3 0.0 1.9 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PH PF00169.24 EXF73324.1 - 5.3e-05 23.3 0.0 0.00079 19.5 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 EXF73324.1 - 0.0063 16.6 0.6 0.014 15.5 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain Pkinase PF00069.20 EXF73325.1 - 5.1e-63 212.6 0.0 7.9e-63 212.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF73325.1 - 3.9e-28 98.2 0.0 6.4e-28 97.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EXF73325.1 - 1e-10 41.5 0.0 8.9e-09 35.3 0.0 2.7 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.1 EXF73325.1 - 0.0016 17.4 0.0 0.0065 15.4 0.0 1.9 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EXF73325.1 - 0.13 11.6 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL zf-H2C2_2 PF13465.1 EXF73326.1 - 2e-10 40.4 12.9 1.6e-05 24.9 0.2 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EXF73326.1 - 5.7e-10 38.9 11.5 2.5e-05 24.3 3.1 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF73326.1 - 4.1e-07 29.8 8.7 0.00026 21.1 1.6 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EXF73326.1 - 9e-06 25.7 1.5 2.5e-05 24.3 1.0 1.8 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EXF73326.1 - 7.9e-05 22.6 5.7 0.00015 21.7 1.4 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EXF73326.1 - 0.00069 19.4 7.7 0.0051 16.6 1.1 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EXF73326.1 - 0.036 14.1 0.8 0.036 14.1 0.5 2.1 2 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.1 EXF73326.1 - 0.81 9.4 3.8 7.5 6.3 0.2 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type zf-H2C2_5 PF13909.1 EXF73326.1 - 5 7.5 7.1 10 6.5 1.4 3.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain RAP1 PF07218.6 EXF73326.1 - 6.7 4.6 5.0 1.3 7.0 1.1 1.4 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) Rax2 PF12768.2 EXF73327.1 - 1.3e-87 293.6 18.0 1.4e-79 267.2 0.0 5.6 4 2 1 5 5 5 4 Cortical protein marker for cell polarity Syndecan PF01034.15 EXF73327.1 - 0.18 11.4 0.2 0.45 10.2 0.2 1.6 1 0 0 1 1 1 0 Syndecan domain P34-Arc PF04045.9 EXF73328.1 - 9.4e-102 339.4 0.2 1.2e-101 339.0 0.1 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc WD40 PF00400.27 EXF73329.1 - 1.3e-69 227.8 24.6 2.5e-08 33.5 0.0 12.0 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp12 PF04003.7 EXF73329.1 - 1.1e-19 70.3 0.1 1.8e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EXF73329.1 - 9e-06 24.0 0.3 0.024 12.8 0.0 4.5 4 1 1 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EXF73329.1 - 0.00027 19.8 2.6 1.5 7.4 0.0 5.0 2 2 0 4 4 4 1 Nup133 N terminal like eIF2A PF08662.6 EXF73329.1 - 0.003 17.2 0.2 0.24 11.0 0.0 4.1 5 1 0 5 5 5 1 Eukaryotic translation initiation factor eIF2A Alg6_Alg8 PF03155.10 EXF73330.1 - 2.3e-129 432.3 24.2 2.1e-81 274.1 7.8 2.0 2 0 0 2 2 2 2 ALG6, ALG8 glycosyltransferase family DUF4337 PF14235.1 EXF73330.1 - 0.21 11.3 1.7 0.47 10.2 1.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) BRO1 PF03097.13 EXF73331.1 - 4e-10 39.0 0.0 5.4e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain Aldedh PF00171.17 EXF73332.1 - 1.4e-125 419.2 0.0 1.5e-124 415.8 0.0 1.9 1 1 0 1 1 1 1 Aldehyde dehydrogenase family CAP_N PF01213.14 EXF73332.1 - 6.5 5.9 7.4 7.3 5.7 4.5 1.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal COPIIcoated_ERV PF07970.7 EXF73333.1 - 2.7e-74 249.5 0.6 3.3e-73 245.9 0.2 2.5 2 1 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EXF73333.1 - 9.9e-35 118.4 0.0 3.5e-34 116.6 0.0 1.9 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) CSTF2_hinge PF14327.1 EXF73334.1 - 6e-31 106.3 2.2 1.2e-30 105.4 1.5 1.5 1 0 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 RRM_1 PF00076.17 EXF73334.1 - 5e-22 77.3 0.0 8.3e-22 76.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF73334.1 - 3.9e-16 58.7 0.0 7.7e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF73334.1 - 5.3e-08 32.5 0.0 7.7e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF_C PF14304.1 EXF73334.1 - 6.1e-07 28.6 3.6 6.1e-07 28.6 2.5 2.8 3 0 0 3 3 3 1 Transcription termination and cleavage factor C-terminal Spo7_2_N PF15407.1 EXF73334.1 - 0.097 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Sporulation protein family 7 CFEM PF05730.6 EXF73335.1 - 7.5e-16 57.7 14.6 1.2e-15 57.0 10.1 1.3 1 0 0 1 1 1 1 CFEM domain adh_short PF00106.20 EXF73336.1 - 3.7e-27 95.2 0.1 5.6e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF73336.1 - 8.9e-17 61.6 0.0 1.3e-16 61.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF73336.1 - 3.7e-12 46.2 0.0 5.9e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EXF73336.1 - 2.7e-10 40.5 0.0 6.2e-10 39.3 0.0 1.6 1 1 1 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EXF73336.1 - 7e-05 22.5 0.0 0.00023 20.8 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EXF73336.1 - 0.0057 15.8 0.0 0.0076 15.4 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EXF73336.1 - 0.067 12.6 0.0 0.18 11.2 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family COesterase PF00135.23 EXF73337.1 - 4.3e-91 306.2 0.0 5.2e-86 289.4 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF73337.1 - 0.00012 21.6 0.0 0.00052 19.6 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF917 PF06032.7 EXF73338.1 - 2.4e-95 319.0 1.5 4.2e-95 318.2 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EXF73338.1 - 3.1e-47 161.0 12.9 2.9e-46 157.8 4.3 3.4 2 1 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EXF73338.1 - 1.2e-25 90.0 2.3 1.8e-24 86.1 0.2 2.7 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.15 EXF73338.1 - 0.00041 19.7 3.1 0.00069 18.9 0.0 2.7 3 1 0 3 3 3 1 BadF/BadG/BcrA/BcrD ATPase family StbA PF06406.6 EXF73338.1 - 0.16 10.9 2.7 0.82 8.5 0.0 2.9 3 0 0 3 3 3 0 StbA protein Fungal_trans PF04082.13 EXF73339.1 - 5.7e-38 130.2 0.0 8.3e-38 129.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF73339.1 - 1e-06 28.5 12.7 1.6e-06 27.8 8.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Band_3_cyto PF07565.8 EXF73339.1 - 0.13 11.7 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Amidohydro_3 PF07969.6 EXF73340.1 - 2.3e-42 145.6 2.2 2.8e-42 145.3 1.6 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EXF73340.1 - 2e-10 40.3 0.4 4e-09 36.1 0.1 2.8 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 EXF73340.1 - 0.017 15.1 0.2 0.017 15.1 0.1 2.7 2 1 0 2 2 2 0 Amidohydrolase Amidohydro_1 PF01979.15 EXF73340.1 - 0.11 12.1 2.3 0.1 12.2 0.3 2.0 2 1 0 2 2 2 0 Amidohydrolase family Cellulase PF00150.13 EXF73341.1 - 5.7e-17 61.8 0.9 1.1e-16 60.9 0.6 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Peptidase_M14 PF00246.19 EXF73342.1 - 2.2e-74 250.5 0.1 3e-74 250.1 0.1 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Propep_M14 PF02244.11 EXF73342.1 - 1.7e-05 24.4 0.0 4.8e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Carboxypeptidase activation peptide NmrA PF05368.8 EXF73343.1 - 8.7e-09 34.9 0.0 1.1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF73343.1 - 0.00021 21.3 0.0 0.00032 20.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Beta_helix PF13229.1 EXF73344.1 - 1.4e-09 37.9 10.9 1.4e-09 37.9 7.6 2.4 2 1 1 3 3 3 1 Right handed beta helix region Chondroitinas_B PF14592.1 EXF73344.1 - 0.00023 20.1 0.1 0.00039 19.3 0.1 1.3 1 0 0 1 1 1 1 Chondroitinase B DUF1565 PF07602.6 EXF73344.1 - 0.00099 18.3 1.6 0.0036 16.4 0.0 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1565) Orthoreo_P10 PF07204.6 EXF73345.1 - 0.0042 16.7 0.0 0.0064 16.2 0.0 1.2 1 0 0 1 1 1 1 Orthoreovirus membrane fusion protein p10 Vfa1 PF08432.5 EXF73345.1 - 0.012 15.6 1.7 0.012 15.6 1.2 1.4 1 1 1 2 2 2 0 AAA-ATPase Vps4-associated protein 1 COG2 PF06148.6 EXF73345.1 - 0.32 10.8 3.0 0.32 10.8 0.9 1.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 YqjK PF13997.1 EXF73345.1 - 0.36 11.0 0.0 0.36 11.0 0.0 2.7 3 0 0 3 3 3 0 YqjK-like protein Bap31 PF05529.7 EXF73345.1 - 0.44 9.9 3.7 0.61 9.5 2.5 1.4 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Atg14 PF10186.4 EXF73345.1 - 0.74 8.6 9.6 0.83 8.5 6.3 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4337 PF14235.1 EXF73345.1 - 0.8 9.5 4.4 1.5 8.6 2.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) BEX PF04538.7 EXF73345.1 - 1.2 9.3 9.5 2.7 8.2 6.2 1.8 1 1 1 2 2 2 0 Brain expressed X-linked like family APG6 PF04111.7 EXF73345.1 - 2 7.4 7.1 2.2 7.2 4.9 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EXF73345.1 - 4.5 6.8 7.4 5 6.6 4.0 1.7 1 1 0 1 1 1 0 IncA protein CENP-Q PF13094.1 EXF73345.1 - 6.9 6.6 9.4 39 4.2 6.5 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Na_K-ATPase PF00287.13 EXF73346.1 - 0.0018 17.1 0.2 0.002 16.9 0.1 1.2 1 0 0 1 1 1 1 Sodium / potassium ATPase beta chain DivIC PF04977.10 EXF73346.1 - 0.013 14.9 6.5 0.038 13.4 1.4 2.7 2 0 0 2 2 2 0 Septum formation initiator TMF_TATA_bd PF12325.3 EXF73346.1 - 0.015 15.0 10.6 0.015 15.0 7.3 2.7 2 1 1 3 3 2 0 TATA element modulatory factor 1 TATA binding RRN3 PF05327.6 EXF73346.1 - 0.015 13.3 2.2 0.027 12.6 1.5 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 MtrA PF04208.9 EXF73346.1 - 0.029 13.8 1.1 0.18 11.2 0.0 2.3 1 1 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit A DUF3422 PF11902.3 EXF73346.1 - 0.048 12.5 6.0 0.14 10.9 3.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3422) NPV_P10 PF05531.7 EXF73346.1 - 0.063 13.5 6.7 0.034 14.3 2.7 2.2 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein SpecificRecomb PF10136.4 EXF73346.1 - 0.13 10.2 5.9 0.17 9.8 4.1 1.1 1 0 0 1 1 1 0 Site-specific recombinase DUF3373 PF11853.3 EXF73346.1 - 0.15 10.5 8.6 1.1 7.6 5.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3373) APG6 PF04111.7 EXF73346.1 - 0.15 11.0 18.8 0.013 14.5 8.5 2.0 1 1 1 2 2 2 0 Autophagy protein Apg6 MutS_III PF05192.13 EXF73346.1 - 0.16 11.7 7.4 0.077 12.7 2.2 2.0 2 0 0 2 2 2 0 MutS domain III eIF-4B PF06273.6 EXF73346.1 - 0.16 10.6 4.0 0.22 10.2 2.8 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DUF21 PF01595.15 EXF73346.1 - 0.22 10.7 4.0 0.085 12.1 0.6 1.8 2 1 0 2 2 2 0 Domain of unknown function DUF21 DUF2959 PF11172.3 EXF73346.1 - 0.33 10.6 9.4 0.2 11.4 2.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2959) DUF342 PF03961.8 EXF73346.1 - 0.43 8.9 11.5 0.22 9.8 6.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF342) FlaC_arch PF05377.6 EXF73346.1 - 0.51 10.2 7.1 0.29 11.0 2.3 2.6 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.7 EXF73346.1 - 0.68 9.7 9.6 3 7.6 3.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4083 PF13314.1 EXF73346.1 - 1.1 9.0 5.2 0.29 10.9 0.4 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4083) DUF2762 PF10960.3 EXF73346.1 - 1.5 8.6 9.8 28 4.5 3.9 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2762) ACCA PF03255.9 EXF73346.1 - 1.6 8.2 8.5 1.1 8.8 3.8 2.1 1 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Peptidase_S49_N PF08496.5 EXF73346.1 - 2.8 7.7 13.0 0.26 11.0 5.6 1.8 2 1 0 2 2 1 0 Peptidase family S49 N-terminal CM_2 PF01817.16 EXF73346.1 - 2.8 8.0 6.6 2 8.5 0.1 2.7 1 1 0 2 2 2 0 Chorismate mutase type II Vfa1 PF08432.5 EXF73346.1 - 4 7.4 14.0 0.2 11.6 5.8 1.7 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF3283 PF11686.3 EXF73346.1 - 6.2 6.7 10.6 1.4 8.8 3.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3283) Striatin PF08232.7 EXF73346.1 - 6.8 7.0 13.1 2.4 8.4 6.7 2.0 1 1 1 2 2 2 0 Striatin family DUF3450 PF11932.3 EXF73346.1 - 8.7 5.5 15.1 0.45 9.7 6.5 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3450) Mannosyl_trans3 PF11051.3 EXF73347.1 - 2e-52 178.2 0.0 2.5e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 Mannosyltransferase putative Nucleotid_trans PF03407.11 EXF73347.1 - 0.098 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Glyco_hydro_3 PF00933.16 EXF73348.1 - 9.5e-51 172.5 0.0 1.2e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF73348.1 - 3.3e-15 56.2 0.4 2.2e-13 50.2 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Bac_luciferase PF00296.15 EXF73349.1 - 2.5e-56 191.0 0.4 3.7e-56 190.5 0.3 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.11 EXF73350.1 - 5.9e-32 110.7 34.9 5.6e-31 107.5 20.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Mac-1 PF09028.5 EXF73350.1 - 0.079 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Mac 1 DUF1614 PF07758.6 EXF73350.1 - 0.63 9.7 6.4 0.08 12.6 0.7 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1614) FBPase PF00316.15 EXF73351.1 - 2.1e-48 164.8 0.0 3.5e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase DUF924 PF06041.6 EXF73352.1 - 2e-46 158.0 2.5 4.4e-46 157.0 1.7 1.5 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF924) Ring_hydroxyl_A PF00848.14 EXF73353.1 - 3.6e-35 121.5 5.4 1.8e-34 119.2 3.8 2.0 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 EXF73353.1 - 2.1e-15 56.0 0.0 4.4e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain p450 PF00067.17 EXF73354.1 - 1.5e-74 251.2 0.0 1.7e-74 250.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CorA PF01544.13 EXF73355.1 - 3.5e-05 22.9 0.9 5.9e-05 22.2 0.6 1.4 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Ninjurin PF04923.7 EXF73355.1 - 0.027 14.1 1.1 3 7.6 0.1 2.3 2 0 0 2 2 2 0 Ninjurin Baculo_44 PF04631.7 EXF73355.1 - 0.036 12.6 0.1 0.051 12.1 0.1 1.1 1 0 0 1 1 1 0 Baculovirus hypothetical protein p450 PF00067.17 EXF73356.1 - 4.6e-69 233.1 0.0 6.8e-69 232.5 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Cupin_2 PF07883.6 EXF73357.1 - 1.3e-13 50.2 0.2 2.6e-13 49.2 0.1 1.6 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EXF73357.1 - 0.073 12.5 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Cupin Flavin_Reduct PF01613.13 EXF73358.1 - 6.2e-22 78.0 0.0 9.2e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Fungal_trans PF04082.13 EXF73359.1 - 1.3e-12 47.2 0.7 3.4e-12 45.7 0.1 1.9 1 1 1 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF73359.1 - 2.3e-08 33.8 10.8 2.3e-08 33.8 7.5 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Beta-lactamase PF00144.19 EXF73360.1 - 2.8e-35 121.9 0.0 3.7e-35 121.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase KfrA_N PF11740.3 EXF73360.1 - 0.063 13.7 0.0 0.13 12.7 0.0 1.5 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Fungal_trans PF04082.13 EXF73361.1 - 6.7e-18 64.4 0.0 1.5e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF73361.1 - 7.8e-09 35.3 10.5 2e-08 34.0 7.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-DHHC PF01529.15 EXF73361.1 - 4 6.8 7.0 8.3 5.7 4.8 1.5 1 0 0 1 1 1 0 DHHC palmitoyltransferase NmrA PF05368.8 EXF73362.1 - 1.7e-28 99.4 0.0 2.7e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF73362.1 - 3.3e-20 72.8 0.1 7.4e-20 71.7 0.0 1.6 1 0 0 1 1 1 1 NADH(P)-binding Amidohydro_1 PF01979.15 EXF73362.1 - 8.1e-19 68.4 0.5 3.7e-08 33.4 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EXF73362.1 - 5.7e-15 54.8 0.1 5.2e-14 51.8 0.0 2.7 2 1 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 EXF73362.1 - 5.8e-09 36.3 2.0 0.0062 16.6 0.1 3.4 3 0 0 3 3 3 2 Amidohydrolase Amidohydro_3 PF07969.6 EXF73362.1 - 2.5e-06 27.0 4.8 4e-05 23.0 0.0 2.6 3 0 0 3 3 3 2 Amidohydrolase family Epimerase PF01370.16 EXF73362.1 - 0.001 18.5 0.0 0.0026 17.2 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EXF73362.1 - 0.0026 16.5 0.1 0.0063 15.2 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NYN_YacP PF05991.6 EXF73362.1 - 0.0049 16.6 0.1 0.013 15.2 0.1 1.6 1 0 0 1 1 1 1 YacP-like NYN domain adh_short PF00106.20 EXF73362.1 - 0.049 13.5 1.9 0.19 11.6 0.1 2.6 2 0 0 2 2 2 0 short chain dehydrogenase Semialdhyde_dh PF01118.19 EXF73362.1 - 0.091 13.0 0.6 0.63 10.3 0.0 2.7 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain FAA_hydrolase PF01557.13 EXF73363.1 - 2e-60 203.9 0.0 2.7e-60 203.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Glyoxalase PF00903.20 EXF73364.1 - 3.7e-09 36.6 4.6 0.0011 18.9 2.7 2.9 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EXF73364.1 - 7.8e-07 29.6 0.0 0.00038 21.0 0.0 2.5 2 1 0 2 2 2 2 Glyoxalase-like domain adh_short_C2 PF13561.1 EXF73365.1 - 6.2e-28 98.1 0.0 8e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EXF73365.1 - 2.4e-24 86.1 0.0 4.9e-24 85.1 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EXF73365.1 - 2.3e-08 33.9 0.0 1e-07 31.7 0.0 1.8 1 1 0 1 1 1 1 KR domain p450 PF00067.17 EXF73366.1 - 8.4e-37 126.7 0.0 9.5e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EXF73367.1 - 1.1e-13 51.0 4.9 6.9e-13 48.3 0.6 2.9 2 1 0 2 2 2 1 FAD binding domain SE PF08491.5 EXF73367.1 - 1.9e-06 26.9 0.0 1.2e-05 24.3 0.0 2.1 1 1 0 1 1 1 1 Squalene epoxidase NAD_binding_8 PF13450.1 EXF73367.1 - 3.2e-05 23.8 0.2 8.6e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF73367.1 - 0.0029 16.5 2.0 0.0099 14.8 0.4 2.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF73367.1 - 0.067 12.0 0.6 0.12 11.2 0.4 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EXF73367.1 - 0.12 12.7 0.3 0.34 11.3 0.2 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Cys_Met_Meta_PP PF01053.15 EXF73368.1 - 9.5e-126 419.1 0.0 1.1e-125 418.9 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EXF73368.1 - 2.4e-09 36.7 1.3 4.3e-09 35.8 0.9 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EXF73368.1 - 7.8e-05 21.7 0.1 0.00013 21.0 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.6 EXF73368.1 - 0.0012 17.2 0.1 0.0018 16.6 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.16 EXF73368.1 - 0.0038 16.4 0.0 0.0072 15.5 0.0 1.5 1 0 0 1 1 1 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 EXF73368.1 - 0.012 14.0 0.1 0.019 13.4 0.1 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Aminotran_5 PF00266.14 EXF73368.1 - 0.022 13.5 0.3 0.14 10.8 0.1 2.0 1 1 1 2 2 2 0 Aminotransferase class-V TNV_CP PF03898.8 EXF73368.1 - 0.062 12.3 0.1 0.11 11.5 0.1 1.4 1 0 0 1 1 1 0 Satellite tobacco necrosis virus coat protein FAD_binding_3 PF01494.14 EXF73369.1 - 3.6e-18 65.7 1.0 7.9e-12 44.8 0.1 2.3 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EXF73369.1 - 5.2e-10 38.7 0.5 3.5e-06 26.1 0.1 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF73369.1 - 6.7e-08 31.8 0.1 1.2e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EXF73369.1 - 5.8e-06 26.2 0.5 2e-05 24.5 0.4 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF73369.1 - 7.8e-06 25.9 0.2 3.1e-05 23.9 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF73369.1 - 2.1e-05 23.2 0.3 0.00071 18.1 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EXF73369.1 - 0.00011 21.2 0.1 0.0042 15.9 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EXF73369.1 - 0.00045 20.5 0.2 0.01 16.1 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EXF73369.1 - 0.00069 18.8 0.7 0.0011 18.0 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EXF73369.1 - 0.0066 15.5 0.1 0.013 14.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EXF73369.1 - 0.011 14.7 0.8 4.4 6.1 0.0 2.9 3 0 0 3 3 3 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EXF73369.1 - 0.019 14.5 0.1 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EXF73369.1 - 0.02 14.5 0.1 0.046 13.3 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EXF73369.1 - 0.023 14.7 0.5 0.086 12.8 0.3 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sugar_tr PF00083.19 EXF73370.1 - 2.3e-76 257.2 15.0 2.8e-76 256.9 10.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF73370.1 - 2.8e-22 78.9 21.1 2.8e-22 78.9 14.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EXF73370.1 - 3.4e-05 22.4 11.9 0.0091 14.4 2.1 2.4 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 EXF73370.1 - 0.0093 15.7 0.0 0.0093 15.7 0.0 3.8 5 0 0 5 5 5 1 MFS_1 like family But2 PF09792.4 EXF73371.1 - 5.7e-17 61.8 0.7 9.9e-17 61.0 0.4 1.5 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain PAP2_3 PF14378.1 EXF73372.1 - 6.3e-39 133.4 6.1 1.1e-38 132.7 4.2 1.4 1 0 0 1 1 1 1 PAP2 superfamily PAP2 PF01569.16 EXF73372.1 - 0.00066 19.3 5.2 0.00066 19.3 3.6 1.8 1 1 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 EXF73372.1 - 0.0024 18.0 0.1 0.0024 18.0 0.1 2.6 3 1 0 3 3 3 1 PAP2 superfamily C-terminal Glyco_hydro_28 PF00295.12 EXF73373.1 - 3e-35 121.7 1.8 4.4e-35 121.1 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 SGL PF08450.7 EXF73375.1 - 1.2e-10 41.2 0.2 5e-08 32.6 0.0 2.7 2 2 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EXF73375.1 - 0.0062 16.4 0.0 7.2 6.7 0.0 3.1 3 0 0 3 3 3 2 NHL repeat Pkinase PF00069.20 EXF73377.1 - 1.9e-72 243.5 0.0 3e-72 242.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF73377.1 - 2.4e-37 128.4 0.0 6.1e-37 127.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF73377.1 - 0.00035 19.6 0.3 0.43 9.5 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EXF73377.1 - 0.0091 15.7 0.3 0.18 11.5 0.0 2.7 2 2 1 3 3 3 2 Phosphotransferase enzyme family Fungal_trans_2 PF11951.3 EXF73378.1 - 6.5e-49 166.5 10.4 2.1e-48 164.8 7.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF73378.1 - 3.6e-07 29.9 7.3 8.4e-07 28.8 5.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RVT_1 PF00078.22 EXF73379.1 - 4.9e-09 35.8 0.0 9.4e-09 34.9 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MFS_1 PF07690.11 EXF73380.1 - 1.6e-41 142.2 45.2 1.6e-41 142.2 31.3 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF73380.1 - 1.7e-14 53.2 10.0 1.7e-14 53.2 6.9 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EXF73380.1 - 0.00071 17.9 19.2 0.0011 17.3 13.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EXF73380.1 - 0.19 10.0 27.4 0.073 11.4 1.0 3.1 2 1 1 3 3 3 0 MFS/sugar transport protein AMP-binding PF00501.23 EXF73381.1 - 2.5e-13 49.2 0.1 7e-07 27.9 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme NPCC PF08058.6 EXF73382.1 - 1.5e-31 109.1 0.1 4e-31 107.8 0.1 1.6 1 1 0 1 1 1 1 Nuclear pore complex component Hid1 PF12722.2 EXF73383.1 - 1.6e-263 876.5 0.0 8.3e-263 874.1 0.0 1.8 1 1 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EXF73383.1 - 3.5e-85 286.5 0.0 5e-85 286.0 0.0 1.2 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Ank_4 PF13637.1 EXF73383.1 - 0.14 12.7 0.0 7.9 7.1 0.0 3.0 3 0 0 3 3 3 0 Ankyrin repeats (many copies) EHN PF06441.7 EXF73384.1 - 1.9e-20 72.8 0.2 3.2e-20 72.1 0.1 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EXF73384.1 - 0.0055 16.6 0.1 0.02 14.7 0.1 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family TaqI_C PF12950.2 EXF73384.1 - 0.037 13.7 0.0 0.066 12.9 0.0 1.3 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain DUF3720 PF12517.3 EXF73384.1 - 4.2 8.1 9.0 0.51 11.0 0.7 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3720) TIMELESS PF04821.9 EXF73385.1 - 2.5e-92 308.9 0.2 2.5e-92 308.9 0.1 3.0 3 0 0 3 3 3 2 Timeless protein TIMELESS_C PF05029.8 EXF73385.1 - 6.9e-34 117.7 29.7 6.9e-34 117.7 20.6 3.3 2 1 0 2 2 2 1 Timeless protein C terminal region 3HCDH_N PF02737.13 EXF73386.1 - 5.5e-53 179.2 1.1 7.7e-53 178.8 0.7 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EXF73386.1 - 7.5e-35 119.2 0.0 1.6e-34 118.1 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Saccharop_dh PF03435.13 EXF73386.1 - 0.00022 20.3 0.2 0.00032 19.7 0.1 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 EXF73386.1 - 0.00023 21.0 0.1 0.00078 19.3 0.1 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DAO PF01266.19 EXF73386.1 - 0.0045 15.9 0.6 0.0081 15.1 0.4 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.11 EXF73386.1 - 0.0073 15.7 0.4 0.079 12.3 0.1 2.2 1 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA TrkA_N PF02254.13 EXF73386.1 - 0.025 14.5 0.0 0.32 11.0 0.0 2.2 2 0 0 2 2 2 0 TrkA-N domain NAD_Gly3P_dh_N PF01210.18 EXF73386.1 - 0.027 14.1 1.8 0.072 12.8 1.2 1.8 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_3 PF13738.1 EXF73386.1 - 0.029 14.4 0.8 0.07 13.1 0.5 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF73386.1 - 0.071 13.5 0.1 0.17 12.3 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EXF73386.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 EXF73386.1 - 0.082 13.3 3.4 0.23 11.8 1.5 2.4 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EXF73386.1 - 0.11 11.6 0.4 0.24 10.5 0.2 1.7 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 EXF73386.1 - 0.12 12.2 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Homeobox PF00046.24 EXF73388.1 - 1.2e-17 63.2 2.8 2.2e-17 62.4 2.0 1.4 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EXF73388.1 - 0.0034 17.0 0.1 0.0086 15.7 0.1 1.7 1 0 0 1 1 1 1 Homeobox KN domain MFS_1 PF07690.11 EXF73389.1 - 3.8e-24 85.0 35.5 5.1e-24 84.6 24.6 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Inh PF02974.9 EXF73391.1 - 0.24 10.9 2.0 0.37 10.3 1.4 1.2 1 0 0 1 1 1 0 Protease inhibitor Inh Fungal_trans_2 PF11951.3 EXF73392.1 - 1.6e-07 30.2 0.0 2.2e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_C50 PF03568.12 EXF73393.1 - 5.1e-112 374.3 0.0 8e-112 373.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C50 TPR_12 PF13424.1 EXF73393.1 - 2.3e-09 37.0 27.3 0.00079 19.3 1.4 6.5 6 1 0 6 6 6 3 Tetratricopeptide repeat Apc3 PF12895.2 EXF73393.1 - 0.029 14.5 0.0 0.029 14.5 0.0 5.0 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EXF73393.1 - 0.049 13.4 8.6 6.1 6.8 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EXF73393.1 - 0.059 13.1 4.9 3.1 7.8 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EXF73393.1 - 0.19 11.7 21.5 2.5 8.2 0.1 7.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_14 PF13428.1 EXF73393.1 - 3.1 8.6 20.9 11 7.0 0.0 7.4 7 1 1 8 8 8 0 Tetratricopeptide repeat DUF2360 PF10152.4 EXF73394.1 - 0.0097 16.1 1.4 0.013 15.7 1.0 1.2 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) DUF3708 PF12501.3 EXF73394.1 - 3.2 7.5 5.9 0.4 10.5 0.7 1.8 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter SIR2 PF02146.12 EXF73395.1 - 7.7e-31 107.1 0.0 1.4e-30 106.3 0.0 1.4 1 1 0 1 1 1 1 Sir2 family Cation_efflux PF01545.16 EXF73396.1 - 4.8e-56 189.9 0.7 6.5e-56 189.4 0.5 1.2 1 0 0 1 1 1 1 Cation efflux family UreE_C PF05194.7 EXF73396.1 - 0.1 12.6 18.4 0.33 11.0 1.2 3.4 3 0 0 3 3 3 0 UreE urease accessory protein, C-terminal domain Med3 PF11593.3 EXF73396.1 - 0.37 9.9 4.7 0.54 9.4 3.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal FGGY_C PF02782.11 EXF73397.1 - 7e-28 97.6 0.0 1.1e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EXF73397.1 - 7.9e-22 77.7 0.0 8.3e-13 48.2 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain HEAT PF02985.17 EXF73399.1 - 0.00045 20.0 0.7 8.3 6.7 0.0 4.8 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 EXF73399.1 - 0.00052 20.2 3.1 0.05 13.8 0.1 4.3 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 EXF73399.1 - 0.0036 17.7 6.0 0.23 11.9 0.0 4.9 5 0 0 5 5 5 1 HEAT-like repeat RNase_H PF00075.19 EXF73400.1 - 4.4e-15 56.1 0.0 7.9e-15 55.3 0.0 1.4 1 0 0 1 1 1 1 RNase H Ribosomal_L1 PF00687.16 EXF73401.1 - 3.5e-51 173.6 0.3 4.2e-51 173.4 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family SNF PF00209.13 EXF73401.1 - 0.088 11.2 0.1 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 Sodium:neurotransmitter symporter family DUF2428 PF10350.4 EXF73402.1 - 4.6e-60 202.8 0.0 1.3e-59 201.2 0.0 1.9 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 EXF73402.1 - 0.00022 21.0 13.8 0.062 13.4 0.0 6.4 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 EXF73402.1 - 0.012 16.1 1.2 0.012 16.1 0.8 4.8 4 0 0 4 4 4 0 HEAT-like repeat Proteasom_PSMB PF10508.4 EXF73402.1 - 0.068 11.4 1.8 4.4 5.4 0.2 3.1 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit DUF3074 PF11274.3 EXF73403.1 - 3.7e-58 196.1 2.1 2.7e-54 183.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3074) Macoilin PF09726.4 EXF73403.1 - 1.2 7.3 20.9 1.9 6.6 14.5 1.2 1 0 0 1 1 1 0 Transmembrane protein DUF3584 PF12128.3 EXF73403.1 - 1.7 5.9 28.0 2.8 5.1 19.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 EXF73403.1 - 2 7.0 21.7 3.5 6.2 15.0 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein CAF-1_p150 PF11600.3 EXF73403.1 - 2.5 7.4 46.9 0.053 12.8 26.5 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Exonuc_VII_L PF02601.10 EXF73403.1 - 2.8 7.0 18.2 5.3 6.1 12.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit GRAM PF02893.15 EXF73404.1 - 0.098 12.1 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 GRAM domain DUF2183 PF09949.4 EXF73407.1 - 8.3e-19 67.3 0.1 1.6e-18 66.4 0.1 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) DUF2411 PF10304.4 EXF73408.1 - 3.8e-13 48.5 0.2 1e-12 47.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) DUF2435 PF10363.4 EXF73408.1 - 4e-13 49.0 3.3 4e-13 49.0 0.2 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF2435) HEAT_2 PF13646.1 EXF73408.1 - 0.018 15.2 2.2 0.63 10.3 0.0 3.5 2 1 0 2 2 2 0 HEAT repeats Adaptin_N PF01602.15 EXF73408.1 - 0.019 13.3 0.1 0.046 12.0 0.0 1.6 1 0 0 1 1 1 0 Adaptin N terminal region DnaG_DnaB_bind PF08278.6 EXF73408.1 - 0.033 14.4 1.5 0.62 10.2 0.1 2.8 2 0 0 2 2 2 0 DNA primase DnaG DnaB-binding RNA_pol_Rpc82 PF05645.8 EXF73408.1 - 0.055 13.0 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 DNA_alkylation PF08713.6 EXF73408.1 - 0.075 12.5 0.0 0.34 10.4 0.0 2.0 2 0 0 2 2 2 0 DNA alkylation repair enzyme RTTN_N PF14726.1 EXF73408.1 - 0.43 11.1 5.0 0.42 11.2 0.5 2.8 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning AT_hook PF02178.14 EXF73409.1 - 0.16 11.7 23.2 0.066 12.9 1.7 3.5 3 0 0 3 3 3 0 AT hook motif Thr_synth_N PF14821.1 EXF73410.1 - 8e-28 96.2 0.0 1.9e-27 95.0 0.0 1.7 1 0 0 1 1 1 1 Threonine synthase N terminus PALP PF00291.20 EXF73410.1 - 1e-19 70.9 0.0 7.7e-19 68.0 0.0 1.9 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADIP PF11559.3 EXF73412.1 - 0.0001 22.2 7.8 0.00041 20.2 2.9 2.1 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding CCDC155 PF14662.1 EXF73412.1 - 0.04 13.5 4.9 0.066 12.7 0.9 2.2 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 HALZ PF02183.13 EXF73412.1 - 0.052 13.2 7.8 10 5.8 0.0 4.2 4 0 0 4 4 4 0 Homeobox associated leucine zipper Sec2p PF06428.6 EXF73412.1 - 0.093 12.5 0.9 0.97 9.3 0.0 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p Leu_zip PF15294.1 EXF73412.1 - 0.11 11.6 3.3 0.09 11.8 0.8 1.7 2 0 0 2 2 2 0 Leucine zipper Zip PF02535.17 EXF73412.1 - 0.19 10.7 7.1 0.32 9.9 4.9 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter APG6 PF04111.7 EXF73412.1 - 0.5 9.3 2.5 0.66 8.9 0.2 1.9 2 0 0 2 2 2 0 Autophagy protein Apg6 Rootletin PF15035.1 EXF73412.1 - 6.9 6.6 11.5 4.7 7.1 2.7 2.5 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF904 PF06005.7 EXF73412.1 - 7 7.0 11.0 21 5.4 0.3 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF904) ABM PF03992.11 EXF73413.1 - 2.1e-05 24.4 0.1 0.00012 22.0 0.0 2.1 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase FAD_binding_4 PF01565.18 EXF73414.1 - 5.7e-27 93.8 0.2 8.9e-27 93.2 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 EXF73414.1 - 2e-23 82.9 0.0 2.7e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Ferritin_2 PF13668.1 EXF73415.1 - 9e-18 64.5 0.1 1.5e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain FKBP_C PF00254.23 EXF73416.1 - 3.4e-34 116.7 0.0 4.8e-34 116.2 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Cytomega_UL20A PF05984.7 EXF73416.1 - 0.0061 16.7 0.0 0.011 15.8 0.0 1.4 1 0 0 1 1 1 1 Cytomegalovirus UL20A protein F420_oxidored PF03807.12 EXF73417.1 - 5.4e-06 26.7 0.1 9.5e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EXF73417.1 - 4.3e-05 23.4 0.0 6.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EXF73417.1 - 0.00068 18.8 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EXF73417.1 - 0.0079 15.5 0.1 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain PDH PF02153.12 EXF73417.1 - 0.012 14.5 0.1 0.017 13.9 0.0 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase Mut7-C PF01927.11 EXF73417.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Mut7-C RNAse domain 3HCDH_N PF02737.13 EXF73417.1 - 0.037 13.6 0.1 0.06 12.9 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RPEL PF02755.10 EXF73419.1 - 4.8e-22 76.5 1.6 4.3e-11 41.7 0.1 2.4 2 0 0 2 2 2 2 RPEL repeat HET PF06985.6 EXF73420.1 - 7.4e-21 74.7 8.2 1.3e-18 67.5 1.0 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) adh_short PF00106.20 EXF73421.1 - 1.6e-30 106.2 0.9 1.9e-30 105.9 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF73421.1 - 3.1e-16 59.9 0.1 4.2e-16 59.4 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF73421.1 - 6.6e-13 48.7 0.3 9e-13 48.2 0.2 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EXF73421.1 - 0.00031 20.4 1.7 0.00059 19.5 1.2 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Bac_luciferase PF00296.15 EXF73421.1 - 0.011 14.8 0.1 0.013 14.6 0.1 1.1 1 0 0 1 1 1 0 Luciferase-like monooxygenase Peptidase_M14 PF00246.19 EXF73422.1 - 3.2e-37 128.6 0.1 4.1e-37 128.2 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase Amidase PF01425.16 EXF73423.1 - 6.4e-68 229.6 0.1 1.7e-66 224.9 0.1 2.1 1 1 0 1 1 1 1 Amidase Cupin_3 PF05899.7 EXF73423.1 - 0.00016 21.0 0.0 0.0006 19.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF861) EutQ PF06249.7 EXF73423.1 - 0.0031 17.0 0.0 0.0055 16.2 0.0 1.3 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ BBE PF08031.7 EXF73424.1 - 0.0003 20.6 0.1 0.00057 19.7 0.1 1.4 1 0 0 1 1 1 1 Berberine and berberine like MOSC_N PF03476.11 EXF73425.1 - 5.9e-10 38.8 0.0 1.3e-09 37.8 0.0 1.7 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EXF73425.1 - 4.8e-07 29.3 0.0 7.1e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 MOSC domain NmrA PF05368.8 EXF73426.1 - 7.2e-14 51.6 0.2 1.1e-13 50.9 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF73426.1 - 1.4e-11 44.6 0.1 2.1e-11 44.1 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_2 PF03446.10 EXF73426.1 - 3e-05 23.9 0.0 6.3e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EXF73426.1 - 0.00041 20.4 0.1 0.0008 19.5 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EXF73426.1 - 0.00042 20.0 0.1 0.00069 19.3 0.1 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EXF73426.1 - 0.019 14.7 0.2 0.045 13.4 0.1 1.7 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus LytR_C PF13399.1 EXF73426.1 - 0.032 14.6 0.3 0.19 12.1 0.0 2.1 2 0 0 2 2 2 0 LytR cell envelope-related transcriptional attenuator Epimerase PF01370.16 EXF73426.1 - 0.058 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.13 EXF73427.1 - 2.9e-10 39.9 8.4 6.3e-10 38.8 5.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF73427.1 - 1.5e-08 33.8 0.2 2.5e-08 33.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain PLA2_B PF01735.13 EXF73428.1 - 3.9e-85 285.8 4.6 1.3e-84 284.1 3.2 1.7 1 1 0 1 1 1 1 Lysophospholipase catalytic domain PHP PF02811.14 EXF73429.1 - 4.1e-09 36.4 0.0 7e-09 35.7 0.0 1.4 1 1 0 1 1 1 1 PHP domain Hist_deacetyl PF00850.14 EXF73430.1 - 1.3e-60 205.2 0.0 2.2e-60 204.5 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain RTP801_C PF07809.6 EXF73430.1 - 0.024 14.2 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 RTP801 C-terminal region TGT PF01702.13 EXF73432.1 - 3.8e-84 281.6 0.0 4.8e-84 281.3 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Mit_ribos_Mrp51 PF11709.3 EXF73433.1 - 3.4e-84 282.7 0.0 4.1e-84 282.4 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit Wound_ind PF08186.6 EXF73433.1 - 0.066 13.1 0.8 0.23 11.3 0.6 1.9 1 0 0 1 1 1 0 Wound-inducible basic protein family Ribosomal_S17e PF00833.13 EXF73434.1 - 1.7e-57 192.4 0.3 2.1e-57 192.1 0.2 1.0 1 0 0 1 1 1 1 Ribosomal S17 Cryptochrome_C PF12546.3 EXF73434.1 - 0.012 16.2 0.0 0.017 15.8 0.0 1.2 1 0 0 1 1 1 0 Blue/Ultraviolet sensing protein C terminal RPAP2_Rtr1 PF04181.8 EXF73435.1 - 1.2e-19 70.1 0.1 2.3e-19 69.2 0.1 1.4 1 0 0 1 1 1 1 Rtr1/RPAP2 family SH3_1 PF00018.23 EXF73436.1 - 2.7e-08 33.0 0.1 2.7e-08 33.0 0.1 2.0 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EXF73436.1 - 4.5e-07 29.2 0.0 8.3e-07 28.4 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EXF73436.1 - 1.3e-06 27.8 0.1 2.9e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain p450 PF00067.17 EXF73437.1 - 8.8e-24 83.8 0.0 1.7e-23 82.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 VASP_tetra PF08776.6 EXF73437.1 - 0.0047 16.2 0.6 0.0092 15.2 0.4 1.4 1 0 0 1 1 1 1 VASP tetramerisation domain p450 PF00067.17 EXF73438.1 - 2.4e-53 181.2 0.0 3.4e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 EXF73439.1 - 1.2e-08 34.5 0.0 2.3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF73439.1 - 2e-07 30.7 0.3 1.1e-06 28.3 0.2 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EXF73439.1 - 0.018 15.9 0.0 0.036 14.9 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AATase PF07247.7 EXF73440.1 - 0.0014 17.2 0.0 0.0025 16.4 0.0 1.5 1 1 0 1 1 1 1 Alcohol acetyltransferase Condensation PF00668.15 EXF73440.1 - 0.0043 15.9 0.3 0.0077 15.1 0.2 1.4 1 0 0 1 1 1 1 Condensation domain IGPD PF00475.13 EXF73440.1 - 0.086 12.6 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Imidazoleglycerol-phosphate dehydratase MutS_II PF05188.12 EXF73441.1 - 0.13 12.2 1.8 0.15 12.0 0.2 1.9 2 0 0 2 2 2 0 MutS domain II zf-C2H2 PF00096.21 EXF73442.1 - 0.003 17.7 0.5 0.003 17.7 0.4 3.8 4 0 0 4 4 4 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF73442.1 - 0.088 13.1 0.5 0.088 13.1 0.4 3.8 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EXF73442.1 - 0.24 11.6 3.4 0.14 12.3 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding CrtC PF07143.6 EXF73443.1 - 1.8e-06 27.4 0.7 2.6e-06 26.9 0.5 1.3 1 1 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) DUF4367 PF14285.1 EXF73443.1 - 0.06 12.6 0.0 0.094 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4367) Pkinase PF00069.20 EXF73445.1 - 5.8e-37 127.2 0.0 7.7e-37 126.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF73445.1 - 9.9e-18 64.1 0.0 2e-17 63.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF73445.1 - 6.6e-05 22.0 0.0 0.00011 21.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EXF73445.1 - 0.0071 16.1 0.1 0.015 15.0 0.1 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Methyltransf_31 PF13847.1 EXF73447.1 - 6.6e-16 58.2 0.0 9.1e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF73447.1 - 1.3e-15 57.6 0.0 1.9e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF73447.1 - 5.3e-14 51.8 0.0 7.8e-14 51.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EXF73447.1 - 5.3e-12 45.9 0.0 8.6e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF73447.1 - 6.4e-08 32.9 0.0 9.6e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF73447.1 - 2.2e-07 30.7 0.0 3e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF73447.1 - 7.9e-06 25.8 0.0 1.9e-05 24.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF73447.1 - 1.8e-05 25.2 0.0 3e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EXF73447.1 - 3.3e-05 23.6 0.0 0.00021 21.0 0.0 2.0 2 0 0 2 2 2 1 Hypothetical methyltransferase MTS PF05175.9 EXF73447.1 - 0.0046 16.3 0.0 0.008 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EXF73447.1 - 0.063 12.7 0.0 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.7 EXF73447.1 - 0.093 12.0 0.0 0.9 8.8 0.0 2.1 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Ank PF00023.25 EXF73448.1 - 3.1e-19 67.7 2.4 7.6e-06 25.4 0.0 6.1 5 1 0 5 5 5 3 Ankyrin repeat Ank_2 PF12796.2 EXF73448.1 - 2.4e-18 66.2 0.6 4.8e-09 36.4 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EXF73448.1 - 1.1e-16 60.4 0.6 3e-07 30.4 0.0 4.6 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF73448.1 - 1.3e-15 55.9 1.4 0.00025 20.9 0.0 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 EXF73448.1 - 2.8e-15 56.3 1.4 0.00043 20.7 0.0 4.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) DUF2139 PF09910.4 EXF73448.1 - 0.07 12.1 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2139) COG2 PF06148.6 EXF73448.1 - 0.27 11.1 1.9 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 LysM PF01476.15 EXF73449.1 - 4.6e-21 74.4 0.2 7.1e-10 38.6 0.0 2.2 2 0 0 2 2 2 2 LysM domain Peptidase_S8 PF00082.17 EXF73451.1 - 4.5e-43 147.4 21.7 6.8e-43 146.8 15.0 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EXF73451.1 - 1.1e-15 57.9 0.1 2e-15 57.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Pyr_redox_2 PF07992.9 EXF73453.1 - 2.1e-18 66.9 0.0 1.9e-17 63.8 0.0 3.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF73453.1 - 1.2e-08 35.1 0.1 6.4e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans_2 PF11951.3 EXF73454.1 - 1.3e-20 73.3 2.4 2.8e-20 72.2 1.7 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF73454.1 - 1.4e-05 24.9 9.7 1.4e-05 24.9 6.7 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EXF73455.1 - 1.1e-09 38.3 0.0 2.4e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF73455.1 - 3.2e-09 36.9 0.1 3.9e-09 36.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EXF73455.1 - 1.6e-05 24.4 0.1 6.9e-05 22.3 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EXF73455.1 - 0.00029 20.5 0.0 0.00045 19.9 0.0 1.3 1 0 0 1 1 1 1 KR domain Lactococcin PF04369.8 EXF73455.1 - 0.0021 17.9 0.1 0.018 14.9 0.0 2.1 2 0 0 2 2 2 1 Lactococcin-like family Aa_trans PF01490.13 EXF73456.1 - 2.3e-39 135.0 33.2 2.6e-39 134.8 23.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF872 PF05915.7 EXF73456.1 - 0.083 12.7 0.3 0.53 10.1 0.0 2.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) HsbA PF12296.3 EXF73457.1 - 3.7e-09 36.5 0.5 3.7e-09 36.5 0.3 2.3 2 1 0 2 2 2 1 Hydrophobic surface binding protein A Serglycin PF04360.7 EXF73457.1 - 0.18 11.5 1.8 0.31 10.7 1.2 1.5 1 1 0 1 1 1 0 Serglycin YesK PF14150.1 EXF73458.1 - 0.55 10.3 6.9 0.97 9.5 0.3 2.2 1 1 1 2 2 2 0 YesK-like protein peroxidase PF00141.18 EXF73459.1 - 4.3e-31 108.1 0.2 5.7e-31 107.7 0.2 1.3 1 0 0 1 1 1 1 Peroxidase DUF3415 PF11895.3 EXF73459.1 - 4.5e-06 26.4 0.1 1.3e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3415) Zn_clus PF00172.13 EXF73460.1 - 2e-08 34.0 8.9 3.1e-08 33.3 6.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF73460.1 - 0.00028 19.6 0.0 0.00038 19.1 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain CAS_CSE1 PF03378.10 EXF73460.1 - 0.022 13.0 0.1 0.032 12.5 0.1 1.1 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus RTA1 PF04479.8 EXF73461.1 - 1.7e-43 148.7 10.7 2.5e-43 148.1 6.5 1.8 2 1 0 2 2 2 1 RTA1 like protein Med21 PF11221.3 EXF73462.1 - 0.012 15.5 3.8 0.2 11.6 0.0 2.7 2 0 0 2 2 2 0 Subunit 21 of Mediator complex PilJ PF13675.1 EXF73462.1 - 0.018 15.3 2.0 0.52 10.6 0.0 3.3 2 1 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term HoxA13_N PF12284.3 EXF73462.1 - 0.78 9.9 8.2 4.1 7.5 0.0 2.5 2 0 0 2 2 2 0 Hox protein A13 N terminal FUSC PF04632.7 EXF73462.1 - 0.83 8.0 5.9 1.1 7.5 3.7 1.5 1 1 0 1 1 1 0 Fusaric acid resistance protein family YchF-GTPase_C PF06071.8 EXF73463.1 - 5.1e-36 122.3 0.0 1.1e-35 121.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EXF73463.1 - 1.1e-16 60.8 0.0 2.1e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EXF73463.1 - 1e-07 31.3 0.0 2e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Arginosuc_synth PF00764.14 EXF73464.1 - 2.3e-149 497.6 0.0 2.6e-149 497.4 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase Asn_synthase PF00733.16 EXF73464.1 - 0.0036 16.8 0.0 0.0057 16.1 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase QueC PF06508.8 EXF73464.1 - 0.0057 15.9 0.0 0.0091 15.3 0.0 1.3 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC tRNA_Me_trans PF03054.11 EXF73464.1 - 0.086 11.3 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase RabGAP-TBC PF00566.13 EXF73467.1 - 1.4e-32 112.9 0.0 2e-32 112.3 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DIL PF01843.14 EXF73468.1 - 1.1e-19 70.2 0.6 1.5e-12 47.3 0.1 2.6 2 0 0 2 2 2 2 DIL domain Ank_2 PF12796.2 EXF73468.1 - 2.7e-16 59.6 0.0 7.1e-16 58.3 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EXF73468.1 - 3e-15 55.1 0.0 1.1e-06 28.1 0.0 4.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EXF73468.1 - 2.2e-12 47.1 0.1 9.6e-06 25.9 0.0 3.8 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF73468.1 - 1.1e-10 41.4 0.0 1.6e-06 28.1 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF73468.1 - 1e-08 34.5 0.0 0.04 14.1 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat DUF4479 PF14794.1 EXF73468.1 - 0.074 12.6 0.1 0.22 11.1 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4479) Allantoicase PF03561.10 EXF73469.1 - 2e-108 358.5 0.2 2.1e-57 192.8 0.0 2.1 2 0 0 2 2 2 2 Allantoicase repeat Cytochrom_B561 PF03188.11 EXF73470.1 - 1.5e-18 66.9 2.7 1.5e-18 66.9 1.8 1.9 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 PepSY_TM_1 PF13172.1 EXF73470.1 - 0.00011 21.8 0.8 0.00011 21.8 0.5 3.8 5 0 0 5 5 5 2 PepSY-associated TM helix DUF4006 PF13179.1 EXF73470.1 - 0.0016 17.9 0.0 0.37 10.3 0.0 2.7 2 0 0 2 2 2 1 Family of unknown function (DUF4006) DUF4079 PF13301.1 EXF73470.1 - 0.029 14.3 14.7 1.7 8.6 0.3 3.2 1 1 1 3 3 3 0 Protein of unknown function (DUF4079) DUF2306 PF10067.4 EXF73470.1 - 0.053 13.6 1.0 0.053 13.6 0.7 3.0 2 1 1 3 3 3 0 Predicted membrane protein (DUF2306) Ni_hydr_CYTB PF01292.15 EXF73470.1 - 0.055 12.8 12.7 0.035 13.4 1.8 2.7 1 1 2 3 3 3 0 Prokaryotic cytochrome b561 Tmpp129 PF10272.4 EXF73470.1 - 0.15 10.7 0.5 6.1 5.4 0.2 2.0 2 0 0 2 2 2 0 Putative transmembrane protein precursor Cytochrom_B_N PF00033.14 EXF73470.1 - 0.27 10.5 14.1 0.29 10.4 3.0 2.9 1 1 2 3 3 3 0 Cytochrome b(N-terminal)/b6/petB COX15-CtaA PF02628.10 EXF73470.1 - 0.63 8.8 12.4 9.3 5.0 8.6 2.0 1 1 0 1 1 1 0 Cytochrome oxidase assembly protein PepSY_TM_2 PF13703.1 EXF73470.1 - 0.92 9.7 15.4 0.12 12.5 2.7 3.2 2 2 1 3 3 3 0 PepSY-associated TM helix DUF1980 PF09323.5 EXF73470.1 - 1.6 8.4 3.8 0.51 10.0 0.2 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) Chs3p PF12271.3 EXF73471.1 - 1.1e-101 339.6 9.2 1.3e-101 339.4 6.4 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit Lysis_S PF04971.7 EXF73471.1 - 0.0036 16.9 0.0 0.012 15.2 0.0 1.9 1 0 0 1 1 1 1 Lysis protein S YvrJ PF12841.2 EXF73471.1 - 0.057 12.7 0.2 0.11 11.7 0.1 1.5 1 0 0 1 1 1 0 YvrJ protein family YajC PF02699.10 EXF73471.1 - 0.71 9.5 0.0 0.71 9.5 0.0 2.7 3 0 0 3 3 3 0 Preprotein translocase subunit NADH-u_ox-rdase PF10785.4 EXF73471.1 - 3.4 7.9 5.0 6.3 7.1 0.2 3.0 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit MtrB PF05440.7 EXF73472.1 - 0.083 12.9 2.2 2.8 8.0 0.0 4.9 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase subunit B DUF1569 PF07606.6 EXF73472.1 - 0.56 10.1 8.6 9.9 6.0 0.1 5.6 3 1 3 6 6 6 0 Protein of unknown function (DUF1569) Reo_sigmaC PF04582.7 EXF73472.1 - 2.3 7.2 46.5 0.12 11.4 0.1 7.6 4 2 1 7 7 7 0 Reovirus sigma C capsid protein DUF4083 PF13314.1 EXF73472.1 - 5.7 6.8 25.4 31 4.4 0.0 9.8 10 2 2 12 12 12 0 Domain of unknown function (DUF4083) tRNA-synt_2b PF00587.20 EXF73473.1 - 3.7e-22 78.7 0.0 5.2e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EXF73473.1 - 3.4e-12 46.3 4.9 8.4e-12 45.0 3.4 1.7 1 1 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Atg14 PF10186.4 EXF73473.1 - 0.019 13.9 3.1 0.029 13.3 2.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 tRNA-synt_His PF13393.1 EXF73473.1 - 0.071 12.1 0.5 0.15 11.0 0.0 1.8 2 0 0 2 2 2 0 Histidyl-tRNA synthetase Actin PF00022.14 EXF73474.1 - 3.2e-21 75.2 0.0 1e-20 73.5 0.0 1.8 1 1 0 1 1 1 1 Actin Tmpp129 PF10272.4 EXF73474.1 - 0.2 10.3 0.8 0.31 9.7 0.5 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor XPG_I PF00867.13 EXF73475.1 - 5.4e-26 90.4 0.0 1.2e-25 89.4 0.0 1.6 1 0 0 1 1 1 1 XPG I-region APC_CDC26 PF10471.4 EXF73479.1 - 0.00016 22.3 0.5 0.00016 22.3 0.4 2.4 2 1 1 3 3 3 1 Anaphase-promoting complex APC subunit 1 Cytomega_UL20A PF05984.7 EXF73479.1 - 0.67 10.1 6.7 1.8 8.8 2.6 2.6 3 0 0 3 3 3 0 Cytomegalovirus UL20A protein DNA_pol_phi PF04931.8 EXF73479.1 - 8.9 3.9 7.5 12 3.5 5.2 1.1 1 0 0 1 1 1 0 DNA polymerase phi PAP_central PF04928.12 EXF73480.1 - 0.053 12.3 0.0 0.085 11.6 0.0 1.2 1 0 0 1 1 1 0 Poly(A) polymerase central domain RGS PF00615.14 EXF73481.1 - 6.2e-11 42.4 0.0 9e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain RRM_1 PF00076.17 EXF73484.1 - 2.5e-13 49.4 0.1 1.3e-05 24.7 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF73484.1 - 1.9e-12 46.9 0.1 9e-05 22.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF73484.1 - 8.3e-07 28.7 0.0 3.8e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2201_N PF13203.1 EXF73484.1 - 3 6.9 8.9 0.98 8.5 0.8 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain Proteasom_Rpn13 PF04683.8 EXF73485.1 - 3.1e-25 88.0 0.0 5.2e-25 87.3 0.0 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor L27_2 PF09045.5 EXF73485.1 - 0.013 14.9 0.1 0.027 14.0 0.1 1.4 1 0 0 1 1 1 0 L27_2 EF1_GNE PF00736.14 EXF73486.1 - 2.1e-30 104.2 1.7 4.2e-30 103.2 1.2 1.5 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain EF-1_beta_acid PF10587.4 EXF73486.1 - 8.5e-14 51.3 9.7 8.5e-14 51.3 6.7 2.7 3 0 0 3 3 3 1 Eukaryotic elongation factor 1 beta central acidic region Sld5 PF05916.6 EXF73486.1 - 1.6e-10 41.2 0.0 4.4e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 GINS complex protein GST_C_3 PF14497.1 EXF73486.1 - 0.00014 22.3 0.0 0.00053 20.4 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EXF73486.1 - 0.00025 20.9 0.0 0.001 19.0 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Sulfate_transp PF00916.15 EXF73487.1 - 3.7e-32 111.4 0.2 9.3e-32 110.1 0.1 1.7 1 0 0 1 1 1 1 Sulfate transporter family cNMP_binding PF00027.24 EXF73487.1 - 1.3e-17 63.3 0.0 2.9e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.16 EXF73487.1 - 2.2e-10 39.9 0.0 4e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 STAS domain Stk19 PF10494.4 EXF73488.1 - 5.4e-62 209.4 0.0 6.5e-62 209.1 0.0 1.1 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 Kinesin PF00225.18 EXF73489.1 - 1.7e-94 316.2 0.0 2.7e-94 315.5 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain LMP PF04778.7 EXF73489.1 - 0.16 11.6 5.1 0.31 10.7 0.5 3.4 3 1 1 4 4 4 0 LMP repeated region DUF4337 PF14235.1 EXF73489.1 - 0.16 11.7 1.8 0.33 10.7 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Tho2 PF11262.3 EXF73489.1 - 0.96 8.4 1.1 1.5 7.7 0.8 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF4407 PF14362.1 EXF73489.1 - 7.8 5.3 8.0 5.8 5.7 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HTH_Tnp_Tc5 PF03221.11 EXF73491.1 - 1.9e-06 27.5 1.1 2.7e-06 27.0 0.1 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain zf-C2H2_4 PF13894.1 EXF73491.1 - 0.69 10.3 27.0 0.25 11.7 2.9 4.7 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF73491.1 - 2 8.9 23.1 1.4 9.3 0.3 4.6 4 0 0 4 4 4 0 Zinc finger, C2H2 type Amidase PF01425.16 EXF73492.1 - 1.6e-86 290.9 0.0 2e-86 290.5 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF3237 PF11578.3 EXF73493.1 - 4.2e-26 91.0 0.0 4.9e-26 90.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) MFS_1 PF07690.11 EXF73494.1 - 6.2e-29 100.8 23.5 6.2e-29 100.8 16.3 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1673 PF07895.6 EXF73494.1 - 4.5 6.7 12.2 0.67 9.4 2.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1673) Peptidase_C13 PF01650.13 EXF73495.1 - 0.11 11.7 0.1 0.17 11.1 0.1 1.2 1 0 0 1 1 1 0 Peptidase C13 family DUF3328 PF11807.3 EXF73498.1 - 3e-17 63.0 0.0 4.1e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Asparaginase PF00710.15 EXF73501.1 - 2.1e-58 197.6 0.1 2.4e-58 197.5 0.1 1.0 1 0 0 1 1 1 1 Asparaginase Chromo PF00385.19 EXF73502.1 - 3e-05 23.6 0.1 7e-05 22.4 0.1 1.7 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Methyltransf_16 PF10294.4 EXF73503.1 - 8.9e-17 61.0 0.0 1.4e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EXF73503.1 - 1.3e-06 28.9 0.0 3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF73503.1 - 0.0024 18.2 0.0 0.0045 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF73503.1 - 0.0058 16.0 0.0 0.012 15.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EXF73503.1 - 0.042 13.4 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EXF73503.1 - 0.057 13.4 0.2 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Fungal_trans PF04082.13 EXF73504.1 - 2.4e-22 79.0 0.0 3.8e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF73504.1 - 8.4e-08 31.9 7.9 1.5e-07 31.2 5.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VCBS PF13517.1 EXF73505.1 - 1.7e-32 111.5 36.0 1.1e-11 44.8 1.7 8.3 6 1 2 8 8 8 7 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EXF73505.1 - 1.3e-11 43.8 36.1 0.00014 21.4 0.2 8.4 8 0 0 8 8 8 4 FG-GAP repeat TcdB_toxin_midN PF12256.3 EXF73505.1 - 2.9e-10 39.8 9.2 0.44 9.9 0.0 5.5 4 1 1 5 5 5 5 Insecticide toxin TcdB middle/N-terminal region Lipase_GDSL_2 PF13472.1 EXF73505.1 - 2.3e-08 34.3 0.1 4.9e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EXF73505.1 - 0.00029 20.7 0.9 0.0018 18.1 0.6 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Period_C PF12114.3 EXF73507.1 - 0.13 11.8 3.0 0.22 11.0 2.1 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region CFEM PF05730.6 EXF73508.1 - 1.9e-15 56.3 11.3 2.9e-15 55.8 7.8 1.3 1 0 0 1 1 1 1 CFEM domain NmrA PF05368.8 EXF73510.1 - 4.2e-06 26.1 0.0 4.5e-06 26.0 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF73510.1 - 0.0035 17.3 0.0 0.0044 17.0 0.0 1.0 1 0 0 1 1 1 1 NADH(P)-binding zf-C2H2_jaz PF12171.3 EXF73512.1 - 6.9e-19 67.4 19.4 2.8e-08 33.6 1.2 5.4 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EXF73512.1 - 1.8e-16 59.6 16.3 2.7e-06 27.3 0.3 5.3 5 0 0 5 5 5 3 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EXF73512.1 - 3.9e-11 42.5 31.7 0.025 14.9 0.5 6.7 6 1 0 6 6 6 6 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EXF73512.1 - 2.4e-10 40.4 22.3 0.0019 18.2 0.4 4.9 2 2 2 4 4 4 3 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EXF73512.1 - 2.6e-09 36.7 32.8 0.11 12.8 0.7 6.8 7 0 0 7 7 7 5 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EXF73512.1 - 4.4e-05 23.2 23.4 0.55 10.2 0.5 6.2 6 0 0 6 6 6 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EXF73512.1 - 0.0077 16.4 35.1 0.31 11.4 0.1 6.5 5 1 1 6 6 6 3 Zinc-finger double domain zf-Di19 PF05605.7 EXF73512.1 - 0.015 15.3 0.3 0.015 15.3 0.2 4.6 4 2 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 EXF73512.1 - 0.04 14.1 0.3 0.04 14.1 0.2 5.2 6 0 0 6 6 4 0 C2H2-type zinc-finger domain AKAP95 PF04988.7 EXF73512.1 - 0.37 10.5 11.0 4.1 7.1 0.5 3.7 3 1 1 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) Rad50_zn_hook PF04423.9 EXF73512.1 - 1.3 8.5 5.2 4.6 6.7 0.0 3.4 3 1 1 4 4 4 0 Rad50 zinc hook motif zf-C2HC_2 PF13913.1 EXF73512.1 - 1.6 8.4 13.9 8.2 6.2 0.0 4.8 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-C3HC4_3 PF13920.1 EXF73512.1 - 8.8 6.0 8.0 72 3.1 4.4 3.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SET PF00856.23 EXF73513.1 - 1.4e-11 44.9 0.1 1.5e-09 38.3 0.1 2.6 1 1 0 1 1 1 1 SET domain TPR_11 PF13414.1 EXF73513.1 - 5.1e-06 26.0 6.4 0.0043 16.6 0.0 4.1 4 0 0 4 4 4 2 TPR repeat SAF PF08666.7 EXF73513.1 - 0.012 16.0 0.1 8.3 6.8 0.0 3.0 3 0 0 3 3 3 0 SAF domain TPR_2 PF07719.12 EXF73513.1 - 0.27 11.2 0.1 0.27 11.2 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EXF73513.1 - 1.3 8.7 7.3 3.1 7.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EXF73513.1 - 2 8.4 5.5 28 4.8 0.0 3.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Alk_phosphatase PF00245.15 EXF73514.1 - 4.7e-72 242.9 0.0 9e-72 242.0 0.0 1.4 1 1 0 1 1 1 1 Alkaline phosphatase Sulfatase PF00884.18 EXF73514.1 - 1.2e-06 27.9 0.0 2.3e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EXF73514.1 - 7.5e-06 25.5 0.2 1.4e-05 24.6 0.2 1.5 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EXF73514.1 - 0.0048 15.3 0.1 0.007 14.8 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.13 EXF73514.1 - 0.053 12.9 0.2 0.14 11.4 0.1 1.7 1 0 0 1 1 1 0 Metalloenzyme superfamily PglZ PF08665.7 EXF73514.1 - 0.1 12.2 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 PglZ domain Fungal_trans_2 PF11951.3 EXF73515.1 - 1.7e-31 109.1 16.2 2.9e-20 72.2 6.8 2.1 1 1 1 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF73515.1 - 0.021 14.7 3.9 0.044 13.6 2.7 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.5 EXF73515.1 - 0.42 9.5 5.2 0.74 8.7 3.6 1.3 1 0 0 1 1 1 0 Aflatoxin regulatory protein DUF2561 PF10812.3 EXF73516.1 - 1.6 8.2 5.5 0.78 9.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2561) DEC-1_N PF04625.8 EXF73517.1 - 0.026 13.1 12.0 0.032 12.9 8.3 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region ATP-synt_G PF04718.10 EXF73517.1 - 0.027 15.1 0.1 0.046 14.3 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial ATP synthase g subunit NSP2_assoc PF14758.1 EXF73517.1 - 0.096 12.8 0.4 0.15 12.2 0.2 1.4 1 1 0 1 1 1 0 Non-essential region of nsp2 of arterivirus polyprotein MFS_1 PF07690.11 EXF73518.1 - 7.6e-35 120.2 26.0 8.6e-35 120.0 17.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Chromo PF00385.19 EXF73520.1 - 3.7e-07 29.7 6.6 0.00031 20.3 0.1 2.5 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4317 PF14199.1 EXF73520.1 - 0.035 12.8 0.7 0.07 11.8 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4317) AT_hook PF02178.14 EXF73520.1 - 2.5 8.0 33.0 0.092 12.4 1.0 4.5 4 0 0 4 4 4 0 AT hook motif Ank_2 PF12796.2 EXF73521.1 - 1.9e-61 204.3 2.1 1.3e-15 57.4 0.4 5.4 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EXF73521.1 - 1.6e-29 100.1 16.6 1.5e-05 24.5 0.2 10.1 11 0 0 11 11 11 6 Ankyrin repeat Ank_4 PF13637.1 EXF73521.1 - 4.4e-26 90.7 5.2 4.4e-06 27.0 0.0 7.0 4 1 4 8 8 8 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF73521.1 - 2.5e-21 75.1 14.3 0.0016 18.6 0.7 8.8 3 3 6 9 9 9 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF73521.1 - 5.9e-21 72.4 3.9 0.0018 18.2 0.1 9.2 10 0 0 10 10 10 4 Ankyrin repeat AAA_16 PF13191.1 EXF73521.1 - 2e-06 27.8 0.0 7.3e-06 26.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EXF73521.1 - 2.6e-06 27.1 0.0 7.9e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EXF73521.1 - 2.9e-05 24.2 0.0 7e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 EXF73521.1 - 0.067 12.1 0.0 0.18 10.7 0.0 1.6 2 0 0 2 2 2 0 KAP family P-loop domain AAA PF00004.24 EXF73521.1 - 0.081 13.1 0.0 0.36 11.0 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EXF73521.1 - 0.16 12.1 0.0 0.57 10.3 0.0 2.0 1 0 0 1 1 1 0 RNA helicase IncA PF04156.9 EXF73522.1 - 0.14 11.7 11.4 0.25 10.9 7.9 1.3 1 0 0 1 1 1 0 IncA protein DUF106 PF01956.11 EXF73522.1 - 0.58 9.6 2.1 0.92 9.0 1.5 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 RE_HaeIII PF09556.5 EXF73524.1 - 0.067 12.0 0.1 0.19 10.5 0.0 1.7 2 0 0 2 2 2 0 HaeIII restriction endonuclease DUF1754 PF08555.5 EXF73524.1 - 2.3 8.8 16.4 0.42 11.2 2.7 2.5 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) COesterase PF00135.23 EXF73525.1 - 1.6e-83 281.2 0.0 1e-73 248.8 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF73525.1 - 0.0018 17.8 4.5 0.02 14.4 3.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF73525.1 - 0.0046 16.7 0.2 0.0082 15.9 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Zn_clus PF00172.13 EXF73526.1 - 2.8e-10 39.9 7.4 5.3e-10 39.0 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EXF73527.1 - 9e-85 284.9 21.2 1.1e-84 284.6 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF73527.1 - 1.4e-34 119.3 34.4 2.6e-31 108.6 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 EXF73528.1 - 7.4e-25 87.2 0.5 1.1e-24 86.7 0.4 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF73528.1 - 4.9e-08 32.7 9.8 7.6e-08 32.1 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAA_hydrolase PF01557.13 EXF73529.1 - 3.1e-59 200.0 0.0 4.4e-59 199.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FtsQ PF03799.10 EXF73531.1 - 0.12 12.5 0.1 0.8 9.9 0.0 2.2 3 0 0 3 3 3 0 Cell division protein FtsQ Epimerase PF01370.16 EXF73532.1 - 3e-18 66.1 0.1 4.1e-18 65.6 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF73532.1 - 1.5e-17 64.1 2.6 1.3e-16 61.1 1.8 2.2 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EXF73532.1 - 5.7e-10 38.3 0.0 8.1e-10 37.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EXF73532.1 - 4.1e-08 32.4 1.0 1.2e-07 30.9 0.7 1.7 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EXF73532.1 - 1.4e-05 24.4 0.1 3.4e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EXF73532.1 - 0.00021 20.2 0.0 0.00031 19.7 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EXF73532.1 - 0.0031 17.4 1.6 0.0031 17.4 1.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase MoCF_biosynth PF00994.19 EXF73532.1 - 0.018 14.4 0.0 0.072 12.4 0.0 1.9 1 1 0 1 1 1 0 Probable molybdopterin binding domain F420_oxidored PF03807.12 EXF73532.1 - 0.019 15.3 0.1 0.31 11.5 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Response_reg PF00072.19 EXF73533.1 - 5.9e-21 74.5 0.0 8.6e-20 70.8 0.0 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 EXF73533.1 - 6.2e-21 74.2 0.1 1.6e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EXF73533.1 - 7.2e-12 45.1 0.0 2e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 EXF73533.1 - 8.6e-05 22.7 0.0 0.0025 17.9 0.0 3.1 3 1 0 3 3 3 1 GAF domain DUF3275 PF11679.3 EXF73534.1 - 0.4 10.2 3.9 0.61 9.6 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) DUF4551 PF15087.1 EXF73534.1 - 2.1 6.5 4.0 2.4 6.4 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) zf-MYND PF01753.13 EXF73536.1 - 0.00073 19.3 9.2 0.00073 19.3 6.4 2.1 2 0 0 2 2 2 1 MYND finger DUF3279 PF11682.3 EXF73536.1 - 0.006 16.1 1.9 0.0084 15.6 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3279) PolC_DP2 PF03833.8 EXF73536.1 - 0.0065 14.1 2.7 0.0076 13.9 1.8 1.0 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 zf-HIT PF04438.11 EXF73536.1 - 0.02 14.5 8.1 0.48 10.1 3.6 2.8 2 1 0 2 2 2 0 HIT zinc finger DUF329 PF03884.9 EXF73536.1 - 0.52 9.9 7.2 1.2 8.7 5.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF329) zf-B_box PF00643.19 EXF73536.1 - 3.2 7.7 11.5 0.64 9.9 5.2 1.9 2 0 0 2 2 2 0 B-box zinc finger GATA PF00320.22 EXF73537.1 - 2.1e-14 52.5 5.8 3.6e-14 51.7 4.0 1.4 1 0 0 1 1 1 1 GATA zinc finger Cytochrom_c3_2 PF14537.1 EXF73537.1 - 1.2 9.5 5.2 2.4 8.5 3.2 1.8 1 1 1 2 2 2 0 Cytochrome c3 AA_permease_2 PF13520.1 EXF73538.1 - 3.2e-50 170.9 40.3 4.2e-50 170.5 28.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF73538.1 - 6.4e-19 67.6 39.2 3.1e-18 65.3 19.0 2.3 2 0 0 2 2 2 2 Amino acid permease GAF PF01590.21 EXF73538.1 - 2e-07 31.2 0.1 4.6e-07 30.0 0.1 1.7 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.1 EXF73538.1 - 0.0076 16.3 0.0 0.037 14.1 0.0 2.2 1 1 0 1 1 1 1 GAF domain PHY PF00360.15 EXF73538.1 - 0.024 13.7 0.0 0.051 12.7 0.0 1.4 1 0 0 1 1 1 0 Phytochrome region GAF_2 PF13185.1 EXF73538.1 - 0.024 15.1 0.0 0.079 13.4 0.0 1.9 1 0 0 1 1 1 0 GAF domain Aldo_ket_red PF00248.16 EXF73539.1 - 6.6e-50 169.5 0.0 7.7e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_10 PF00331.15 EXF73540.1 - 2.6e-85 286.2 0.2 3.1e-85 286.0 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 HET PF06985.6 EXF73541.1 - 1.2e-28 100.0 0.0 2.1e-28 99.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Amidohydro_2 PF04909.9 EXF73542.1 - 1.3e-22 80.7 0.0 1.6e-22 80.3 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Abhydrolase_3 PF07859.8 EXF73543.1 - 1.4e-21 77.0 0.0 2.3e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EXF73543.1 - 2e-15 56.3 0.0 2.8e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EXF73543.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family adh_short PF00106.20 EXF73544.1 - 1.5e-24 86.7 0.0 3e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF73544.1 - 3.7e-08 33.2 0.0 1.5e-07 31.2 0.0 1.9 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF73544.1 - 7.6e-05 22.2 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EXF73544.1 - 0.00045 19.0 0.0 0.00064 18.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1776 PF08643.5 EXF73544.1 - 0.0076 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EXF73544.1 - 0.011 15.7 0.0 0.03 14.3 0.0 1.8 1 1 0 1 1 1 0 NADH(P)-binding Pyr_redox_3 PF13738.1 EXF73545.1 - 1.4e-18 67.7 0.0 3.1e-18 66.5 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EXF73545.1 - 7.7e-11 40.8 0.3 1.5e-10 39.9 0.2 1.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EXF73545.1 - 3.5e-10 39.3 1.0 3.1e-09 36.1 0.1 2.5 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EXF73545.1 - 3.7e-06 26.8 0.0 9.3e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Polyketide_cyc2 PF10604.4 EXF73546.1 - 1.5e-07 31.6 0.1 1.7e-07 31.5 0.1 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport FAD_binding_3 PF01494.14 EXF73547.1 - 7.1e-80 268.7 0.0 8.9e-80 268.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EXF73547.1 - 7.7e-39 133.0 0.0 2.2e-38 131.5 0.0 1.7 2 0 0 2 2 2 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.19 EXF73547.1 - 0.00031 19.7 0.1 0.001 17.9 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EXF73547.1 - 0.00053 19.1 0.0 0.0012 18.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EXF73547.1 - 0.0019 17.1 0.2 0.0061 15.5 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase SE PF08491.5 EXF73547.1 - 0.002 17.0 0.0 0.0063 15.3 0.0 1.8 1 1 0 1 1 1 1 Squalene epoxidase FAD_oxidored PF12831.2 EXF73547.1 - 0.0025 16.9 0.2 0.0048 16.0 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF73547.1 - 0.042 13.8 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.16 EXF73547.1 - 0.047 13.2 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 EXF73547.1 - 0.094 12.1 0.3 0.32 10.4 0.1 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 EXF73547.1 - 0.13 12.0 0.1 0.26 11.1 0.0 1.7 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SSF PF00474.12 EXF73548.1 - 5e-20 71.5 27.0 5e-20 71.5 18.7 1.7 2 0 0 2 2 2 1 Sodium:solute symporter family PsbH PF00737.15 EXF73548.1 - 0.03 13.8 1.0 0.03 13.8 0.7 3.3 4 0 0 4 4 4 0 Photosystem II 10 kDa phosphoprotein Phage_holin_1 PF04531.8 EXF73550.1 - 8.7 6.4 7.4 7.9 6.6 0.7 2.5 2 0 0 2 2 2 0 Bacteriophage holin PhyH PF05721.8 EXF73551.1 - 1.1e-19 71.3 0.0 1.4e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 EXF73551.1 - 0.042 14.1 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Transp_cyt_pur PF02133.10 EXF73552.1 - 2.9e-35 121.6 30.4 2.5e-34 118.5 21.1 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Tannase PF07519.6 EXF73553.1 - 9.5e-108 360.9 0.1 1.3e-107 360.4 0.1 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 EXF73553.1 - 2.3e-05 24.1 0.1 0.032 13.9 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF73553.1 - 0.00012 21.3 0.3 0.13 11.5 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EXF73553.1 - 0.00013 21.9 0.0 0.00028 20.8 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF73553.1 - 0.00099 18.7 0.0 0.0017 17.9 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold FAD_binding_3 PF01494.14 EXF73554.1 - 3.2e-07 29.7 0.3 0.019 13.9 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EXF73554.1 - 0.0074 16.1 0.3 0.016 15.0 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF73554.1 - 0.016 15.1 0.1 0.061 13.3 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EXF73554.1 - 0.065 11.6 0.2 0.13 10.7 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein GFO_IDH_MocA PF01408.17 EXF73555.1 - 5.5e-16 59.1 0.0 9.4e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA PF01408.17 EXF73556.1 - 2.6e-21 76.3 0.0 5.4e-21 75.3 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EXF73556.1 - 5.9e-06 26.0 0.2 1.4e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_2 PF03446.10 EXF73556.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_4 PF01565.18 EXF73557.1 - 1e-09 37.9 1.4 1e-09 37.9 1.0 1.5 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 EXF73558.1 - 4.1e-12 45.8 0.1 7.4e-07 28.5 0.0 2.9 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EXF73558.1 - 3.9e-10 39.1 0.0 1.4e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF73558.1 - 7e-08 32.3 0.0 2.3e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EXF73558.1 - 2.3e-05 23.4 0.2 4.7e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EXF73558.1 - 2.6e-05 23.3 0.0 0.18 10.6 0.0 2.9 3 0 0 3 3 3 2 Lycopene cyclase protein HI0933_like PF03486.9 EXF73558.1 - 0.00015 20.3 0.1 0.0027 16.2 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EXF73558.1 - 0.0006 20.1 0.1 0.015 15.7 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF73558.1 - 0.00076 18.4 0.1 0.044 12.6 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EXF73558.1 - 0.00092 19.1 0.0 0.0019 18.1 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF73558.1 - 0.002 18.2 0.0 0.0047 17.0 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EXF73558.1 - 0.016 14.3 0.1 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.12 EXF73558.1 - 0.098 11.7 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Zip PF02535.17 EXF73559.1 - 1.3 7.9 4.3 1.5 7.7 3.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Med19 PF10278.4 EXF73559.1 - 2.7 7.6 11.2 5.8 6.5 7.8 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Nucleo_P87 PF07267.6 EXF73559.1 - 8.9 4.8 9.2 13 4.3 6.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CDC45 PF02724.9 EXF73559.1 - 9.2 4.1 10.6 14 3.5 7.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Mago-bind PF09282.5 EXF73560.1 - 0.075 12.6 0.3 15 5.2 0.0 2.4 2 0 0 2 2 2 0 Mago binding SspK PF08176.7 EXF73560.1 - 0.1 12.6 0.4 18 5.4 0.0 2.4 2 0 0 2 2 2 0 Small acid-soluble spore protein K family Methyltransf_22 PF13383.1 EXF73561.1 - 7.6e-20 71.4 0.1 1e-19 71.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 EXF73561.1 - 5e-07 29.8 0.0 7.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain MFS_1 PF07690.11 EXF73562.1 - 2e-32 112.3 52.8 4.1e-31 107.9 36.5 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF4407 PF14362.1 EXF73562.1 - 0.44 9.4 0.0 0.44 9.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Aldedh PF00171.17 EXF73564.1 - 4.5e-152 506.6 0.0 5.1e-152 506.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family p450 PF00067.17 EXF73565.1 - 4.8e-39 134.1 0.0 6.5e-39 133.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Taeniidae_ag PF05596.6 EXF73565.1 - 0.15 11.9 0.1 0.58 10.0 0.0 2.0 2 0 0 2 2 2 0 Taeniidae antigen PTR2 PF00854.16 EXF73567.1 - 8.8e-33 113.5 6.5 8.8e-33 113.5 4.5 2.3 1 1 1 2 2 2 1 POT family DUF1469 PF07332.6 EXF73567.1 - 0.019 14.7 0.6 0.019 14.7 0.4 4.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1469) Herpes_US9 PF06072.6 EXF73567.1 - 0.025 14.4 1.1 5.6 6.8 0.0 2.9 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 CcmH PF03918.9 EXF73567.1 - 0.16 10.9 0.4 17 4.3 0.0 2.6 2 1 0 2 2 2 0 Cytochrome C biogenesis protein DUF443 PF04276.7 EXF73567.1 - 0.67 9.3 5.6 0.29 10.5 1.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF443) DUF718 PF05336.8 EXF73568.1 - 0.024 14.4 0.7 0.076 12.8 0.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF718) CBM_21 PF03370.8 EXF73569.1 - 8.1e-36 122.4 1.0 1.5e-35 121.6 0.7 1.4 1 0 0 1 1 1 1 Putative phosphatase regulatory subunit Corona_NS8 PF12093.3 EXF73570.1 - 0.077 13.3 1.0 0.099 12.9 0.2 1.5 2 0 0 2 2 2 0 Coronavirus NS8 protein vMSA PF00695.14 EXF73570.1 - 0.66 9.1 3.2 0.64 9.1 1.8 1.3 1 1 0 1 1 1 0 Major surface antigen from hepadnavirus AAA PF00004.24 EXF73573.1 - 3e-17 63.0 1.1 9.4e-17 61.4 0.0 2.4 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EXF73573.1 - 0.00036 20.6 1.1 0.014 15.5 0.2 3.4 1 1 1 2 2 2 1 AAA domain KaiC PF06745.8 EXF73573.1 - 0.0041 16.2 0.3 0.015 14.4 0.2 2.0 1 0 0 1 1 1 1 KaiC AAA_16 PF13191.1 EXF73573.1 - 0.0066 16.4 0.1 0.0066 16.4 0.1 3.6 4 1 1 5 5 5 1 AAA ATPase domain AAA_19 PF13245.1 EXF73573.1 - 0.0071 16.0 0.1 0.023 14.4 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain Gtr1_RagA PF04670.7 EXF73573.1 - 0.01 14.9 0.0 0.034 13.2 0.0 1.9 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region Zot PF05707.7 EXF73573.1 - 0.02 14.3 0.3 1.7 8.0 0.2 2.7 1 1 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_5 PF07728.9 EXF73573.1 - 0.04 13.6 0.0 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EXF73573.1 - 0.043 14.6 2.0 0.15 12.8 0.4 2.8 2 1 0 2 2 2 0 AAA domain Ank PF00023.25 EXF73574.1 - 6.2e-37 123.5 1.1 6.5e-09 35.1 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat Ank_2 PF12796.2 EXF73574.1 - 7.3e-35 119.1 0.0 7e-18 64.7 0.0 2.9 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) zf-DHHC PF01529.15 EXF73574.1 - 1.9e-34 118.5 10.2 1.9e-34 118.5 7.1 1.6 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.1 EXF73574.1 - 7e-30 102.3 6.0 4e-09 36.4 0.0 5.9 3 1 4 7 7 7 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EXF73574.1 - 7.1e-27 93.2 8.0 3.4e-10 40.1 0.1 5.1 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF73574.1 - 3.4e-25 85.6 1.7 8.5e-08 31.7 0.0 6.5 7 0 0 7 7 7 4 Ankyrin repeat SRPRB PF09439.5 EXF73575.1 - 4.3e-25 87.9 0.0 1.3e-24 86.4 0.0 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EXF73575.1 - 6.4e-05 22.8 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EXF73575.1 - 0.0019 18.2 0.0 0.0043 17.0 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EXF73575.1 - 0.0023 18.0 0.0 0.0063 16.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain Arf PF00025.16 EXF73575.1 - 0.003 16.8 0.0 1.9 7.6 0.0 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Septin PF00735.13 EXF73575.1 - 0.0049 15.9 0.0 0.0077 15.2 0.0 1.2 1 0 0 1 1 1 1 Septin GTP_EFTU PF00009.22 EXF73575.1 - 0.066 12.6 0.0 0.33 10.3 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EXF73575.1 - 0.07 13.4 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 ABC transporter AAA PF00004.24 EXF73575.1 - 0.081 13.1 0.0 3.2 7.9 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EXF73575.1 - 0.095 11.8 0.1 0.19 10.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 cobW PF02492.14 EXF73575.1 - 0.11 11.9 0.1 1.7 8.0 0.1 2.2 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PALP PF00291.20 EXF73576.1 - 4.4e-60 203.4 0.1 5.6e-60 203.1 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EXF73576.1 - 4.6e-09 35.9 0.0 1e-07 31.6 0.0 2.5 2 0 0 2 2 2 1 CBS domain Pyr_redox_2 PF07992.9 EXF73577.1 - 5.7e-15 55.7 2.0 1.8e-07 31.2 0.0 3.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF73577.1 - 8.7e-13 48.4 0.1 1.7e-09 37.9 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF73577.1 - 1.5e-08 33.9 2.0 0.006 15.5 0.0 4.0 4 0 0 4 4 4 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EXF73577.1 - 0.0004 20.5 1.4 1.3 8.9 0.2 3.3 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EXF73577.1 - 0.0012 17.5 0.1 0.97 7.9 0.0 2.5 2 0 0 2 2 2 2 Tryptophan halogenase Thi4 PF01946.12 EXF73577.1 - 0.0086 15.1 1.1 2.1 7.3 0.0 2.9 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.17 EXF73577.1 - 0.021 13.6 3.5 2.8 6.7 0.0 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A K_oxygenase PF13434.1 EXF73577.1 - 0.035 13.0 0.0 0.086 11.7 0.0 1.6 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EXF73577.1 - 0.046 13.4 1.0 12 5.6 0.0 3.7 4 0 0 4 4 4 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EXF73577.1 - 0.081 11.8 0.2 0.76 8.6 0.0 2.5 2 1 1 3 3 3 0 Lycopene cyclase protein FAD_oxidored PF12831.2 EXF73577.1 - 0.19 10.7 0.0 0.19 10.7 0.0 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EXF73577.1 - 0.3 10.1 1.7 0.63 9.0 0.1 2.1 2 0 0 2 2 2 0 FAD binding domain Dodecin PF07311.7 EXF73578.1 - 0.12 12.4 0.2 0.24 11.4 0.1 1.5 1 0 0 1 1 1 0 Dodecin AAA PF00004.24 EXF73582.1 - 4.7e-17 62.4 0.0 1e-16 61.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EXF73582.1 - 0.00057 19.9 0.0 0.0016 18.4 0.0 1.8 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EXF73582.1 - 0.0017 19.1 1.4 0.016 16.0 0.2 3.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EXF73582.1 - 0.0024 18.0 0.0 0.021 14.9 0.0 2.2 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EXF73582.1 - 0.014 14.4 0.0 0.026 13.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EXF73582.1 - 0.017 14.8 0.0 0.047 13.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EXF73582.1 - 0.052 13.2 0.3 0.12 12.0 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 EXF73582.1 - 0.058 13.7 0.0 0.25 11.6 0.0 2.2 1 0 0 1 1 1 0 AAA domain FAD_binding_4 PF01565.18 EXF73583.1 - 7e-21 74.1 0.1 1.1e-20 73.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pro-kuma_activ PF09286.6 EXF73584.1 - 3.3e-28 98.5 0.1 3.3e-27 95.2 0.0 2.5 3 0 0 3 3 3 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EXF73584.1 - 1.3e-06 27.7 0.6 2.2e-06 27.0 0.4 1.5 1 0 0 1 1 1 1 Subtilase family DUF2985 PF11204.3 EXF73586.1 - 1.3e-36 124.1 1.2 3.6e-36 122.7 0.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2985) PEMT PF04191.8 EXF73586.1 - 9.4e-08 32.1 3.3 2.5e-07 30.7 0.1 2.8 3 0 0 3 3 3 1 Phospholipid methyltransferase ICMT PF04140.9 EXF73586.1 - 2.1e-07 31.0 0.1 1.1e-06 28.7 0.0 2.1 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Sugar_tr PF00083.19 EXF73587.1 - 8.3e-60 202.6 35.0 1e-59 202.3 24.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF73587.1 - 2.2e-21 75.9 30.9 3.7e-21 75.2 21.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF1304 PF06993.7 EXF73587.1 - 3.3 7.4 12.8 0.71 9.6 1.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1304) Glyco_hyd_65N_2 PF14498.1 EXF73588.1 - 7.6e-61 205.8 0.0 9.9e-61 205.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain NUDE_C PF04880.8 EXF73590.1 - 5.4e-21 75.6 5.5 5.4e-21 75.6 3.8 5.4 2 2 2 4 4 2 1 NUDE protein, C-terminal conserved region WEMBL PF05701.6 EXF73590.1 - 0.0025 16.3 33.3 0.0035 15.8 23.1 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light IncA PF04156.9 EXF73590.1 - 0.0084 15.7 40.2 0.15 11.6 16.5 2.3 1 1 1 2 2 2 2 IncA protein DUF904 PF06005.7 EXF73590.1 - 0.016 15.4 8.3 0.016 15.4 5.8 3.9 2 1 1 4 4 3 0 Protein of unknown function (DUF904) Filament PF00038.16 EXF73590.1 - 0.088 12.2 35.2 0.44 9.9 7.3 2.5 2 1 1 3 3 3 0 Intermediate filament protein ATG16 PF08614.6 EXF73590.1 - 0.11 12.2 34.3 1.8 8.3 12.6 3.0 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.2 EXF73590.1 - 0.17 11.7 41.5 0.24 11.2 17.1 3.6 2 1 1 3 3 3 0 Tropomyosin like DUF3584 PF12128.3 EXF73590.1 - 0.18 9.0 27.0 0.27 8.5 18.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF869 PF05911.6 EXF73590.1 - 0.51 8.5 30.5 2.4 6.2 21.1 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) CENP-F_leu_zip PF10473.4 EXF73590.1 - 0.57 10.0 40.7 0.83 9.5 12.2 3.9 2 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prefoldin_2 PF01920.15 EXF73590.1 - 1.5 8.6 37.2 0.51 10.1 8.0 5.1 2 1 3 5 5 5 0 Prefoldin subunit ERM PF00769.14 EXF73590.1 - 4.9 6.6 34.3 0.47 9.9 7.7 2.3 1 1 1 2 2 2 0 Ezrin/radixin/moesin family AAA_13 PF13166.1 EXF73590.1 - 5.1 5.4 26.0 9.7 4.5 18.0 1.4 1 0 0 1 1 1 0 AAA domain Reo_sigmaC PF04582.7 EXF73590.1 - 8 5.5 7.8 5.5 6.0 1.5 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Glyco_hydro_cc PF11790.3 EXF73593.1 - 4.8e-67 225.8 0.4 5.5e-67 225.6 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core EF1G PF00647.14 EXF73593.1 - 0.042 13.5 0.1 0.076 12.7 0.1 1.3 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain Thiolase_N PF00108.18 EXF73594.1 - 8.8e-71 237.9 0.1 1.4e-70 237.3 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EXF73594.1 - 4.3e-40 135.9 0.2 9.4e-40 134.8 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain Sulfate_transp PF00916.15 EXF73595.1 - 1.3e-52 178.5 2.9 1.3e-52 178.5 2.0 1.6 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EXF73595.1 - 1.1e-29 101.9 3.6 3.3e-29 100.3 2.5 1.9 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EXF73595.1 - 2.8e-16 59.0 0.0 7.5e-16 57.6 0.0 1.7 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.1 EXF73595.1 - 0.0002 21.2 0.0 0.00065 19.6 0.0 1.9 2 1 0 2 2 2 1 STAS domain Abhydrolase_3 PF07859.8 EXF73596.1 - 8.1e-12 45.1 0.1 1.5e-11 44.2 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF73596.1 - 0.00019 21.1 0.0 0.0003 20.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF73596.1 - 0.14 11.3 0.0 8 5.6 0.0 2.1 2 0 0 2 2 2 0 Prolyl oligopeptidase family Hce2 PF14856.1 EXF73597.1 - 3e-16 59.0 0.1 4.5e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor DUF3012 PF11216.3 EXF73597.1 - 0.12 12.0 0.3 0.27 10.9 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) BTB PF00651.26 EXF73598.1 - 0.0029 17.5 0.0 0.0063 16.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain NPP1 PF05630.6 EXF73599.1 - 2.1e-61 207.2 1.6 2.7e-61 206.9 1.1 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) DUF607 PF04678.8 EXF73599.1 - 0.1 12.5 0.1 0.16 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF607 ECH PF00378.15 EXF73600.1 - 4.8e-14 52.0 0.0 8.1e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Formyl_trans_N PF00551.14 EXF73600.1 - 1.6e-10 40.8 0.0 4.2e-09 36.2 0.0 2.6 1 1 1 2 2 2 1 Formyl transferase Formyl_trans_C PF02911.13 EXF73600.1 - 6.5e-09 35.7 0.0 1.6e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain Phospholip_A2_3 PF09056.6 EXF73600.1 - 0.069 13.3 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic phospholipase A2 DUF3636 PF12331.3 EXF73601.1 - 3.4e-28 98.1 0.1 7.2e-28 97.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3636) HAP1_N PF04849.8 EXF73601.1 - 0.0016 17.4 0.0 0.0027 16.7 0.0 1.4 1 0 0 1 1 1 1 HAP1 N-terminal conserved region DUF2890 PF11081.3 EXF73601.1 - 0.0024 17.9 2.2 0.0024 17.9 1.5 2.4 1 1 0 2 2 2 1 Protein of unknown function (DUF2890) TMF_TATA_bd PF12325.3 EXF73601.1 - 0.023 14.4 3.0 0.042 13.5 2.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CTP_transf_1 PF01148.15 EXF73602.1 - 8.2e-79 264.9 28.6 1e-78 264.6 19.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family Aldolase_II PF00596.16 EXF73603.1 - 3.3e-48 163.7 0.2 4.7e-48 163.2 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain ABC2_membrane PF01061.19 EXF73604.1 - 7.5e-82 273.5 64.0 2.6e-45 154.1 14.2 2.7 3 0 0 3 3 2 2 ABC-2 type transporter PDR_CDR PF06422.7 EXF73604.1 - 1.1e-35 121.4 1.4 3.1e-29 100.6 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 EXF73604.1 - 5.6e-34 117.3 2.5 4e-16 59.5 0.0 3.1 4 0 0 4 4 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EXF73604.1 - 9e-16 57.8 37.1 1.6e-11 43.8 7.4 2.9 2 1 1 3 3 3 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 EXF73604.1 - 1.9e-08 34.2 0.1 6.9e-08 32.4 0.1 2.0 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EXF73604.1 - 4.8e-08 32.6 0.1 0.00057 19.3 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 EXF73604.1 - 3.8e-06 26.3 0.0 0.0016 17.9 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EXF73604.1 - 2.1e-05 23.7 0.0 5.9e-05 22.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 EXF73604.1 - 4e-05 23.7 0.0 0.039 13.8 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EXF73604.1 - 4.5e-05 24.2 0.0 0.014 16.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EXF73604.1 - 0.00018 21.6 0.0 0.048 13.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EXF73604.1 - 0.00069 19.3 0.0 0.069 12.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain cobW PF02492.14 EXF73604.1 - 0.00099 18.5 0.0 0.039 13.4 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 EXF73604.1 - 0.001 18.7 0.0 0.29 10.9 0.1 2.6 2 0 0 2 2 2 1 Part of AAA domain MMR_HSR1 PF01926.18 EXF73604.1 - 0.0017 18.2 0.0 0.42 10.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EXF73604.1 - 0.002 18.1 6.9 0.015 15.3 0.2 3.2 4 1 0 4 4 2 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EXF73604.1 - 0.003 17.0 0.8 1.6 8.1 0.0 2.9 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_18 PF13238.1 EXF73604.1 - 0.0037 17.5 0.0 0.042 14.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EXF73604.1 - 0.0059 16.9 3.3 0.011 16.0 0.0 2.9 4 0 0 4 4 3 1 AAA domain AAA_28 PF13521.1 EXF73604.1 - 0.006 16.5 0.0 0.006 16.5 0.0 2.2 3 0 0 3 3 1 1 AAA domain AAA_33 PF13671.1 EXF73604.1 - 0.011 15.6 6.2 0.063 13.1 0.0 3.4 4 0 0 4 4 3 0 AAA domain UPF0079 PF02367.12 EXF73604.1 - 0.015 14.9 1.5 0.072 12.7 0.1 2.4 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 EXF73604.1 - 0.025 13.5 0.0 3.5 6.4 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA PF00004.24 EXF73604.1 - 0.031 14.4 0.1 2 8.6 0.0 3.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EXF73604.1 - 0.051 13.7 0.0 3.4 7.8 0.0 2.5 2 0 0 2 2 2 0 RNA helicase Arch_ATPase PF01637.13 EXF73604.1 - 0.06 13.0 0.1 4.8 6.8 0.0 2.8 3 0 0 3 3 2 0 Archaeal ATPase Miro PF08477.8 EXF73604.1 - 0.089 13.2 0.0 5.3 7.5 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 EXF73604.1 - 0.1 12.0 3.3 3.3 7.0 0.3 2.8 3 0 0 3 3 3 0 AAA-like domain AAA_15 PF13175.1 EXF73604.1 - 0.19 10.7 0.0 0.42 9.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain HeLo PF14479.1 EXF73604.1 - 2.9 7.5 7.1 0.44 10.2 0.1 2.7 2 1 1 3 3 3 0 Prion-inhibition and propagation Oxidored_FMN PF00724.15 EXF73605.1 - 2.3e-89 299.7 0.0 2.6e-89 299.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DAGK_cat PF00781.19 EXF73605.1 - 0.027 13.9 0.1 0.43 10.0 0.1 2.2 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain DJ-1_PfpI PF01965.19 EXF73606.1 - 2.8e-16 59.2 0.0 5.2e-14 51.9 0.0 2.1 1 1 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EXF73606.1 - 0.00017 21.0 0.0 0.00041 19.8 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family Fungal_trans PF04082.13 EXF73607.1 - 1.1e-20 73.6 0.1 1.7e-20 72.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF73607.1 - 3.5e-08 33.2 11.6 5.4e-08 32.6 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.7 EXF73607.1 - 0.047 13.4 4.0 0.1 12.4 2.8 1.6 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Peptidase_S8 PF00082.17 EXF73608.1 - 9.6e-32 110.2 2.6 1.5e-31 109.5 1.8 1.3 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EXF73608.1 - 1.1e-10 41.8 0.0 3.2e-10 40.3 0.0 1.9 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Alpha-L-AF_C PF06964.7 EXF73609.1 - 6.4e-36 123.7 0.0 9.7e-36 123.1 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus HRXXH PF13933.1 EXF73610.1 - 0.0048 16.3 0.2 0.014 14.7 0.0 1.8 2 0 0 2 2 2 1 Putative peptidase family PTS_EIIA_1 PF00358.15 EXF73610.1 - 0.0053 16.3 0.1 0.0094 15.5 0.1 1.3 1 0 0 1 1 1 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 Aspzincin_M35 PF14521.1 EXF73610.1 - 0.01 16.3 0.0 0.1 13.0 0.0 2.5 1 1 0 1 1 1 0 Lysine-specific metallo-endopeptidase Sugar_tr PF00083.19 EXF73611.1 - 5.2e-82 275.8 20.7 6.5e-82 275.4 14.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF73611.1 - 1.6e-19 69.8 45.0 5.1e-18 64.9 17.9 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC_tran PF00005.22 EXF73612.1 - 7.7e-43 146.0 0.0 6.2e-22 78.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EXF73612.1 - 7.8e-17 61.5 27.1 2.2e-11 43.6 3.9 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EXF73612.1 - 7.9e-13 49.0 0.1 0.00013 22.0 0.0 4.4 4 0 0 4 4 4 2 AAA domain SMC_N PF02463.14 EXF73612.1 - 8.1e-09 35.0 0.6 0.042 13.0 0.0 3.5 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EXF73612.1 - 0.00024 21.5 0.1 0.00072 19.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EXF73612.1 - 0.00054 19.4 0.2 0.01 15.3 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SE PF00437.15 EXF73612.1 - 0.0013 17.7 0.2 1.4 7.7 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein Arch_ATPase PF01637.13 EXF73612.1 - 0.0053 16.4 0.2 0.026 14.2 0.0 2.1 2 0 0 2 2 2 1 Archaeal ATPase AAA_16 PF13191.1 EXF73612.1 - 0.0055 16.6 0.3 0.5 10.3 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain AAA_10 PF12846.2 EXF73612.1 - 0.01 15.2 0.4 0.43 9.9 0.0 3.0 3 0 0 3 3 3 0 AAA-like domain DUF258 PF03193.11 EXF73612.1 - 0.014 14.6 0.4 0.05 12.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 NB-ARC PF00931.17 EXF73612.1 - 0.014 14.3 0.0 0.037 12.8 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain AAA_25 PF13481.1 EXF73612.1 - 0.014 14.7 0.3 0.7 9.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EXF73612.1 - 0.019 15.4 0.2 10 6.6 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_19 PF13245.1 EXF73612.1 - 0.037 13.7 0.3 0.33 10.7 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain Rad17 PF03215.10 EXF73612.1 - 0.048 12.3 0.0 0.074 11.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Adeno_IVa2 PF02456.10 EXF73612.1 - 0.058 12.0 0.0 0.098 11.2 0.0 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein Dynamin_N PF00350.18 EXF73612.1 - 0.059 13.1 1.4 0.6 9.9 0.0 2.6 3 0 0 3 3 2 0 Dynamin family AAA_14 PF13173.1 EXF73612.1 - 0.084 12.7 0.0 0.69 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EXF73612.1 - 0.088 12.2 1.0 2.2 7.6 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EXF73612.1 - 0.095 12.8 0.1 0.66 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EXF73612.1 - 0.11 12.6 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 EXF73612.1 - 0.12 11.4 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain DUF2207 PF09972.4 EXF73612.1 - 2.7 6.4 2.7 1.3 7.4 0.2 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) MTHFR PF02219.12 EXF73613.1 - 1.6e-111 371.9 0.0 2.6e-111 371.3 0.0 1.3 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase DUF3425 PF11905.3 EXF73614.1 - 2e-23 82.8 0.9 3.7e-23 81.9 0.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) HTH_Tnp_Tc5 PF03221.11 EXF73615.1 - 6.5e-15 54.6 0.3 0.00047 19.9 0.0 5.2 5 0 0 5 5 5 4 Tc5 transposase DNA-binding domain Homeobox_KN PF05920.6 EXF73615.1 - 1.8e-14 53.1 1.1 1.8e-14 53.1 0.7 2.9 3 0 0 3 3 3 1 Homeobox KN domain Homeobox PF00046.24 EXF73615.1 - 7.6e-06 25.4 0.3 2.1e-05 24.0 0.2 1.8 1 0 0 1 1 1 1 Homeobox domain zf-C2H2 PF00096.21 EXF73615.1 - 0.0037 17.5 19.3 0.026 14.8 2.6 4.4 3 1 1 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF73615.1 - 0.22 11.9 24.5 0.025 14.8 2.9 4.7 4 0 0 4 4 4 0 C2H2-type zinc finger Elf1 PF05129.8 EXF73615.1 - 0.31 10.7 4.7 1.6 8.4 3.3 2.2 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like Patatin PF01734.17 EXF73616.1 - 1.7e-25 90.1 0.0 2.5e-25 89.6 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Tetraspannin PF00335.15 EXF73617.1 - 0.025 13.8 0.1 0.031 13.5 0.1 1.1 1 0 0 1 1 1 0 Tetraspanin family DUF719 PF05334.8 EXF73617.1 - 0.056 13.4 0.2 0.08 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF719) Gly-zipper_OmpA PF13436.1 EXF73618.1 - 3.2 7.4 16.7 7.6 6.2 11.6 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain MFS_1 PF07690.11 EXF73620.1 - 1.7e-22 79.6 25.2 1.7e-22 79.6 17.5 1.7 1 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EXF73620.1 - 0.0083 15.8 4.0 0.19 11.5 0.5 2.9 2 1 0 2 2 2 2 MFS_1 like family 4HBT PF03061.17 EXF73621.1 - 1.3e-06 28.4 0.1 2.1e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily SR-25 PF10500.4 EXF73621.1 - 0.12 11.8 8.5 0.15 11.4 5.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein rRNA_processing PF08524.6 EXF73622.1 - 0.00025 20.8 20.4 0.026 14.3 1.4 2.3 2 0 0 2 2 2 2 rRNA processing Med13_C PF06333.7 EXF73622.1 - 1.9 6.9 4.6 2.4 6.6 3.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal TFIIA PF03153.8 EXF73622.1 - 2.9 7.6 13.0 3.9 7.2 9.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RhoGAP PF00620.22 EXF73623.1 - 7.8e-45 152.2 0.0 7.8e-45 152.2 0.0 2.7 3 2 1 4 4 4 1 RhoGAP domain LIM PF00412.17 EXF73623.1 - 2.2e-12 46.8 18.2 2.5e-06 27.4 1.7 3.2 2 1 0 2 2 2 2 LIM domain SlyX PF04102.7 EXF73623.1 - 0.014 15.7 1.4 0.014 15.7 0.9 3.4 3 1 1 4 4 4 0 SlyX Zn-ribbon_8 PF09723.5 EXF73623.1 - 0.85 9.6 17.3 0.38 10.7 1.0 4.4 4 0 0 4 4 4 0 Zinc ribbon domain Desulfoferrod_N PF06397.7 EXF73623.1 - 2.6 7.5 6.5 10 5.5 0.5 3.0 2 1 1 3 3 3 0 Desulfoferrodoxin, N-terminal domain DUF948 PF06103.6 EXF73623.1 - 9.3 6.1 8.1 19 5.2 0.7 2.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) CLASP_N PF12348.3 EXF73624.1 - 1.9e-136 452.7 0.0 2.7e-88 295.1 0.0 2.7 3 0 0 3 3 3 2 CLASP N terminal HEAT PF02985.17 EXF73624.1 - 2.9e-05 23.7 0.0 6.2 7.1 0.0 5.3 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.1 EXF73624.1 - 0.0013 18.9 0.2 1.1 9.5 0.0 4.7 4 1 1 5 5 5 1 HEAT repeats HEAT_EZ PF13513.1 EXF73624.1 - 0.035 14.6 0.2 19 5.8 0.0 4.4 4 0 0 4 4 4 0 HEAT-like repeat Adaptin_N PF01602.15 EXF73624.1 - 0.042 12.1 0.0 0.52 8.5 0.0 2.6 3 0 0 3 3 3 0 Adaptin N terminal region BSP PF04450.7 EXF73625.1 - 4.2e-76 254.9 0.0 4.9e-76 254.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase of plants and bacteria Peptidase_MA_2 PF13485.1 EXF73625.1 - 6.6e-07 29.4 0.1 1.8e-05 24.7 0.0 2.1 1 1 1 2 2 2 1 Peptidase MA superfamily SprT-like PF10263.4 EXF73625.1 - 0.0082 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 SprT-like family FAP PF07174.6 EXF73625.1 - 1.4 8.1 19.7 2.6 7.2 13.6 1.5 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) FtsJ PF01728.14 EXF73629.1 - 9e-46 156.1 0.0 1.6e-45 155.3 0.0 1.4 1 1 0 1 1 1 1 FtsJ-like methyltransferase CCDC144C PF14915.1 EXF73630.1 - 0.0016 17.4 58.5 0.083 11.7 23.6 3.3 1 1 2 3 3 3 2 CCDC144C protein coiled-coil region AT_hook PF02178.14 EXF73630.1 - 2.7 7.9 11.4 0.29 10.9 2.3 3.3 2 0 0 2 2 2 0 AT hook motif Reo_sigmaC PF04582.7 EXF73630.1 - 4.9 6.2 11.6 0.59 9.2 3.5 2.2 1 1 0 2 2 2 0 Reovirus sigma C capsid protein OST3_OST6 PF04756.8 EXF73631.1 - 6e-23 81.1 0.5 8.6e-23 80.6 0.3 1.2 1 0 0 1 1 1 1 OST3 / OST6 family DUF2561 PF10812.3 EXF73631.1 - 0.022 14.3 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) TctB PF07331.6 EXF73631.1 - 0.052 13.1 0.2 0.052 13.1 0.1 2.5 3 1 0 3 3 3 0 Tripartite tricarboxylate transporter TctB family Glyco_hydro_6 PF01341.12 EXF73632.1 - 9.7e-96 320.7 0.2 1.3e-95 320.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 Glyco_hydro_71 PF03659.9 EXF73632.1 - 0.065 11.6 0.0 0.11 10.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 71 WD40 PF00400.27 EXF73633.1 - 8.7e-62 202.9 22.2 1.2e-11 43.9 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EXF73633.1 - 1.3e-05 23.5 6.7 0.23 9.5 0.1 4.0 1 1 4 5 5 5 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EXF73633.1 - 0.03 12.6 0.0 3.4 5.8 0.1 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain TAF8_C PF10406.4 EXF73634.1 - 1.8e-15 56.6 2.1 9.8e-15 54.3 0.1 2.6 2 0 0 2 2 2 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 EXF73634.1 - 6.4e-10 38.6 0.0 9.3e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.19 EXF73634.1 - 0.055 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 LRR_4 PF12799.2 EXF73635.1 - 1.2e-19 69.5 4.0 1.2e-05 24.8 0.4 4.9 4 2 0 4 4 4 3 Leucine Rich repeats (2 copies) Pkinase PF00069.20 EXF73635.1 - 5.3e-16 58.5 0.0 3.8e-15 55.7 0.0 1.9 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF73635.1 - 8.8e-16 57.7 0.0 4.2e-13 48.9 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase LRR_8 PF13855.1 EXF73635.1 - 1.2e-15 56.9 12.7 4e-08 32.9 0.9 4.2 3 1 2 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 EXF73635.1 - 7.3e-10 37.5 12.5 0.0083 16.0 0.0 7.2 8 0 0 8 8 8 4 Leucine Rich Repeat Kdo PF06293.9 EXF73635.1 - 7.2e-05 21.9 0.0 0.00012 21.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_7 PF13504.1 EXF73635.1 - 0.00015 21.3 10.5 11 6.7 0.1 7.6 7 1 0 7 7 7 1 Leucine rich repeat LRR_6 PF13516.1 EXF73635.1 - 0.00038 20.2 2.4 4 7.8 0.0 5.2 4 0 0 4 4 4 1 Leucine Rich repeat 2OG-FeII_Oxy_2 PF13532.1 EXF73636.1 - 8.8e-27 94.1 0.0 1.3e-26 93.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Isochorismatase PF00857.15 EXF73636.1 - 4.8e-22 78.7 0.0 1.9e-21 76.7 0.0 2.1 2 1 0 2 2 2 1 Isochorismatase family GST_C_3 PF14497.1 EXF73636.1 - 2.7e-07 31.0 0.2 8.7e-07 29.3 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EXF73636.1 - 2e-05 24.4 0.0 3.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EXF73636.1 - 0.001 18.8 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain SHMT PF00464.14 EXF73637.1 - 6.1e-196 650.5 0.0 7.2e-196 650.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.16 EXF73637.1 - 0.00034 19.8 0.0 0.00085 18.5 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EXF73637.1 - 0.012 14.4 0.0 0.018 13.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Ribosomal_L19e PF01280.15 EXF73638.1 - 1.9e-60 202.9 7.8 1.9e-60 202.9 5.4 2.0 1 1 1 2 2 2 1 Ribosomal protein L19e RNase_H2-Ydr279 PF09468.5 EXF73638.1 - 0.0018 17.5 0.2 0.0032 16.7 0.2 1.3 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DUF3554 PF12074.3 EXF73639.1 - 1.1e-77 261.7 16.3 1.2e-77 261.6 5.1 4.7 5 1 0 5 5 5 1 Domain of unknown function (DUF3554) HEAT PF02985.17 EXF73639.1 - 1.4e-36 121.2 38.6 0.015 15.2 0.1 23.2 27 0 0 27 27 26 8 HEAT repeat HEAT_2 PF13646.1 EXF73639.1 - 3.8e-36 123.2 57.3 3.6e-08 33.5 0.0 17.2 9 3 5 14 14 14 9 HEAT repeats HEAT_EZ PF13513.1 EXF73639.1 - 3.5e-31 106.9 66.6 0.00013 22.3 0.0 23.9 21 3 8 29 29 26 11 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EXF73639.1 - 1.8e-14 53.8 0.0 0.17 12.3 0.0 9.6 7 2 1 9 9 9 3 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EXF73639.1 - 1.6e-12 47.2 0.0 0.0032 16.8 0.0 6.0 3 1 2 6 6 6 2 CLASP N terminal ParcG PF10274.4 EXF73639.1 - 3.3e-11 43.4 1.3 0.00073 19.4 0.0 6.5 4 2 1 6 6 6 2 Parkin co-regulated protein Cnd1 PF12717.2 EXF73639.1 - 1.8e-09 37.7 0.0 2.5 7.9 0.0 7.9 4 2 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 EXF73639.1 - 7.3e-08 31.1 11.9 0.11 10.7 3.2 8.1 9 1 1 10 10 10 2 Adaptin N terminal region Ipi1_N PF12333.3 EXF73639.1 - 3.4e-05 23.7 2.1 0.005 16.7 0.0 5.6 5 0 0 5 5 4 1 Rix1 complex component involved in 60S ribosome maturation MMS19_C PF12460.3 EXF73639.1 - 0.065 11.9 12.8 1.1 7.9 0.1 6.4 6 1 2 8 8 8 0 RNAPII transcription regulator C-terminal HEAT_PBS PF03130.11 EXF73639.1 - 0.2 12.2 14.7 54 4.6 0.1 8.4 8 0 0 8 8 7 0 PBS lyase HEAT-like repeat HA2 PF04408.18 EXF73640.1 - 2.7e-17 62.6 0.0 9.6e-17 60.8 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EXF73640.1 - 4.1e-12 45.7 0.1 1e-11 44.5 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EXF73640.1 - 1.1e-10 41.2 0.0 2.4e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EXF73640.1 - 2.1e-08 34.3 0.2 9.3e-08 32.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain OB_NTP_bind PF07717.11 EXF73640.1 - 1.6e-05 24.7 0.0 4.7e-05 23.1 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_29 PF13555.1 EXF73640.1 - 0.003 17.0 0.0 0.0069 15.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EXF73640.1 - 0.005 17.1 0.0 0.019 15.2 0.0 2.0 1 0 0 1 1 1 1 ABC transporter T2SE PF00437.15 EXF73640.1 - 0.024 13.5 0.0 0.049 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein KaiC PF06745.8 EXF73640.1 - 0.03 13.4 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 EXF73640.1 - 0.042 13.5 0.2 0.19 11.3 0.0 2.2 2 0 0 2 2 2 0 NACHT domain DUF258 PF03193.11 EXF73640.1 - 0.084 12.0 0.0 0.19 10.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EXF73640.1 - 1.1 9.5 0.0 1.1 9.5 0.0 3.2 4 0 0 4 4 4 0 AAA domain RRM_1 PF00076.17 EXF73641.1 - 9.8e-43 143.6 0.0 4.9e-12 45.3 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF73641.1 - 1.6e-41 140.1 0.0 5.3e-14 51.9 0.0 4.5 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF73641.1 - 1.9e-23 82.0 0.0 3.8e-10 39.4 0.1 4.6 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EXF73641.1 - 5.7e-09 35.6 0.0 0.0013 18.4 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EXF73641.1 - 0.00017 21.2 0.0 0.36 10.5 0.0 3.1 2 1 1 3 3 3 2 Nup53/35/40-type RNA recognition motif TPR_14 PF13428.1 EXF73641.1 - 0.093 13.4 4.6 0.93 10.3 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat CFEM PF05730.6 EXF73642.1 - 2.6e-12 46.3 7.0 4.3e-12 45.6 4.9 1.3 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.5 EXF73642.1 - 0.00059 19.0 0.5 0.0014 17.9 0.4 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain ATG22 PF11700.3 EXF73642.1 - 0.097 11.1 0.1 0.12 10.8 0.0 1.2 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like TFIIA PF03153.8 EXF73642.1 - 1.4 8.6 5.8 1.7 8.4 4.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Retinal PF15449.1 EXF73642.1 - 3.1 5.3 25.0 3.5 5.1 17.3 1.0 1 0 0 1 1 1 0 Retinal protein Ribosomal_L22 PF00237.14 EXF73643.1 - 2.8e-14 52.9 0.4 2e-12 46.9 0.2 2.5 1 1 0 1 1 1 1 Ribosomal protein L22p/L17e YWFCY PF14293.1 EXF73644.1 - 0.073 12.9 0.0 0.095 12.5 0.0 1.2 1 0 0 1 1 1 0 YWFCY protein Mitochondr_Som1 PF11093.3 EXF73645.1 - 3.4e-13 49.1 0.1 4.3e-13 48.8 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial export protein Som1 TMEM95 PF15203.1 EXF73645.1 - 0.68 9.3 3.4 0.49 9.7 0.5 2.0 2 1 0 2 2 2 0 TMEM95 family Hydrolase_6 PF13344.1 EXF73647.1 - 2.4e-23 81.9 0.0 6.2e-23 80.6 0.0 1.7 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EXF73647.1 - 4.4e-12 45.5 0.0 2.9e-11 42.9 0.0 2.4 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EXF73647.1 - 0.0039 17.4 0.0 3.1 7.9 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EXF73647.1 - 0.024 15.0 0.0 0.069 13.5 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase adh_short PF00106.20 EXF73648.1 - 1.7e-27 96.3 2.1 2.2e-27 96.0 1.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF73648.1 - 9e-20 71.4 0.0 1.1e-19 71.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF73648.1 - 3.2e-09 36.7 0.6 4.8e-09 36.1 0.4 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EXF73648.1 - 0.012 15.6 0.2 0.019 14.9 0.2 1.3 1 0 0 1 1 1 0 NADH(P)-binding Polysacc_synt_2 PF02719.10 EXF73648.1 - 0.034 13.0 0.0 0.063 12.1 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 EXF73648.1 - 0.059 12.7 0.5 0.13 11.6 0.3 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MR_MLE_C PF13378.1 EXF73649.1 - 5.4e-20 71.4 0.0 1.3e-19 70.1 0.0 1.6 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EXF73649.1 - 1.3e-12 48.0 0.0 2.6e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EXF73649.1 - 3.2e-10 40.0 0.0 4.9e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Glyco_hydro_42 PF02449.10 EXF73649.1 - 0.062 12.4 0.0 0.58 9.2 0.0 2.0 2 0 0 2 2 2 0 Beta-galactosidase Fungal_trans PF04082.13 EXF73650.1 - 3.2e-27 95.0 2.4 5.1e-27 94.3 1.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugarporin_N PF11471.3 EXF73650.1 - 0.64 9.7 2.6 1.5 8.5 1.8 1.6 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension Ctr PF04145.10 EXF73651.1 - 2.2e-41 141.2 0.9 2.7e-41 141.0 0.7 1.1 1 0 0 1 1 1 1 Ctr copper transporter family Ferric_reduct PF01794.14 EXF73652.1 - 6.1e-22 78.0 8.5 6.1e-22 78.0 5.9 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EXF73652.1 - 4.4e-14 52.6 0.0 6.8e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EXF73652.1 - 3.4e-10 39.7 0.0 7.4e-10 38.6 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EXF73652.1 - 4e-06 27.3 0.0 1.3e-05 25.6 0.0 1.8 1 1 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF1418 PF07214.7 EXF73652.1 - 3 7.5 8.3 0.83 9.3 0.0 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF1418) Fungal_trans PF04082.13 EXF73653.1 - 3.5e-16 58.8 0.2 5.7e-16 58.1 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF73653.1 - 4.6e-07 29.6 8.6 7.7e-07 28.9 6.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GATase_5 PF13507.1 EXF73655.1 - 3.7e-94 314.4 0.0 5.4e-94 313.8 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EXF73655.1 - 3.6e-41 140.6 0.2 1e-20 74.2 0.0 2.5 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EXF73655.1 - 6.9e-25 87.1 0.1 1.5e-23 82.8 0.0 2.8 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain PQ-loop PF04193.9 EXF73656.1 - 3.1e-18 65.0 5.1 5.1e-13 48.3 1.0 2.7 2 0 0 2 2 2 2 PQ loop repeat MTHFR PF02219.12 EXF73658.1 - 4.1e-101 337.8 0.0 5.7e-101 337.3 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase tRNA-synt_1 PF00133.17 EXF73659.1 - 1.5e-53 181.7 0.0 2.3e-19 68.8 0.2 6.1 2 1 3 5 5 5 5 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 EXF73659.1 - 1.5e-41 141.7 0.0 2.6e-41 140.9 0.0 1.4 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EXF73659.1 - 3.3e-31 108.3 0.1 6.1e-23 81.1 0.0 4.2 3 1 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EXF73659.1 - 4.2e-12 46.0 0.0 8.8e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EXF73659.1 - 0.0071 15.5 0.0 2.2 7.3 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 EXF73659.1 - 0.053 12.3 0.0 0.089 11.5 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (R) tRNA-synt_1c PF00749.16 EXF73659.1 - 0.069 11.7 0.4 5 5.6 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain cobW PF02492.14 EXF73660.1 - 1.6e-38 131.9 0.0 3.4e-38 130.8 0.0 1.5 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MobB PF03205.9 EXF73660.1 - 0.0011 18.6 0.0 0.0026 17.4 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 EXF73660.1 - 0.0071 15.8 0.0 0.017 14.6 0.0 1.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 EXF73660.1 - 0.016 14.7 0.8 0.52 9.8 0.0 3.1 3 0 0 3 3 3 0 P-loop containing region of AAA domain AAA_19 PF13245.1 EXF73660.1 - 0.023 14.4 0.1 0.055 13.2 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 EXF73660.1 - 0.042 13.7 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EXF73660.1 - 0.044 13.9 0.0 0.12 12.5 0.0 1.7 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EXF73660.1 - 0.047 12.6 0.0 0.086 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 EXF73660.1 - 0.06 13.0 0.1 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 NTPase AAA_18 PF13238.1 EXF73660.1 - 0.095 13.0 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EXF73660.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain CENP-T PF15511.1 EXF73661.1 - 0.16 11.1 3.7 0.19 10.9 2.6 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Pyr_redox_2 PF07992.9 EXF73663.1 - 9.8e-15 54.9 2.0 1.9e-13 50.7 1.4 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF73663.1 - 6.1e-12 45.7 0.1 3.7e-10 40.0 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF73663.1 - 4.4e-08 33.4 3.6 0.014 15.4 0.2 3.1 1 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF73663.1 - 2.2e-06 27.5 0.3 0.23 11.2 0.0 3.3 3 0 0 3 3 3 3 FAD-NAD(P)-binding K_oxygenase PF13434.1 EXF73663.1 - 0.00037 19.5 0.2 0.086 11.7 0.0 2.7 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EXF73663.1 - 0.00064 18.7 8.1 0.6 8.9 0.0 3.7 3 1 0 4 4 4 3 FAD dependent oxidoreductase GIDA PF01134.17 EXF73663.1 - 0.014 14.2 3.2 0.41 9.4 0.1 2.7 2 1 1 3 3 3 0 Glucose inhibited division protein A HI0933_like PF03486.9 EXF73663.1 - 0.014 13.8 2.6 0.74 8.2 0.0 3.2 3 1 1 4 4 4 0 HI0933-like protein FAD_binding_2 PF00890.19 EXF73663.1 - 0.025 13.4 0.3 7.4 5.2 0.0 3.1 3 0 0 3 3 3 0 FAD binding domain Lycopene_cycl PF05834.7 EXF73663.1 - 0.028 13.3 0.2 0.27 10.0 0.0 2.4 3 0 0 3 3 3 0 Lycopene cyclase protein PBP PF01161.15 EXF73664.1 - 3.6e-14 52.8 0.0 5.1e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DUF572 PF04502.8 EXF73666.1 - 8.7e-73 245.3 8.0 1e-72 245.1 5.5 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DUF866 PF05907.8 EXF73666.1 - 0.019 14.4 0.3 0.038 13.5 0.2 1.4 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) Spc97_Spc98 PF04130.8 EXF73667.1 - 1.8e-67 227.9 0.0 2.7e-67 227.3 0.0 1.3 1 0 0 1 1 1 1 Spc97 / Spc98 family GCP5-Mod21 PF14609.1 EXF73667.1 - 5.9e-09 34.6 0.2 8.5e-09 34.0 0.1 1.2 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Glyco_transf_15 PF01793.11 EXF73668.1 - 1.3e-137 458.2 9.8 1.6e-137 457.9 6.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase WD40 PF00400.27 EXF73669.1 - 7e-29 98.6 6.6 5.4e-08 32.4 1.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_2 PF13360.1 EXF73669.1 - 0.004 16.6 1.4 0.034 13.5 0.3 2.4 1 1 1 2 2 2 2 PQQ-like domain PQQ_3 PF13570.1 EXF73669.1 - 0.0048 17.1 7.6 1.7 9.0 0.2 4.4 5 0 0 5 5 5 1 PQQ-like domain PQQ PF01011.16 EXF73669.1 - 0.09 12.3 0.7 21 4.9 0.1 3.8 4 0 0 4 4 4 0 PQQ enzyme repeat Kelch_4 PF13418.1 EXF73669.1 - 0.13 12.1 2.4 0.35 10.6 0.0 2.9 3 0 0 3 3 3 0 Galactose oxidase, central domain Aminotran_1_2 PF00155.16 EXF73670.1 - 6.9e-46 156.8 0.0 9.2e-46 156.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Methyltransf_26 PF13659.1 EXF73671.1 - 2.2e-14 53.4 0.0 6.7e-14 51.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF73671.1 - 7.4e-10 38.6 0.0 2.6e-09 36.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF73671.1 - 2.1e-08 33.7 0.0 2.3e-07 30.3 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EXF73671.1 - 2e-06 28.3 0.0 3.7e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EXF73671.1 - 4.9e-06 25.8 0.0 6.9e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 EXF73671.1 - 4.8e-05 23.6 0.0 8.6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF73671.1 - 0.00034 20.3 0.0 0.00069 19.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6_Mtase PF02384.11 EXF73671.1 - 0.00039 19.6 0.0 0.00056 19.0 0.0 1.1 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_32 PF13679.1 EXF73671.1 - 0.00093 18.8 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_10 PF05971.7 EXF73671.1 - 0.0013 17.9 0.0 0.0016 17.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF890) UPF0020 PF01170.13 EXF73671.1 - 0.0072 15.9 0.0 0.021 14.4 0.0 1.7 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_11 PF08241.7 EXF73671.1 - 0.0087 16.5 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EXF73671.1 - 0.028 13.8 0.0 0.046 13.1 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 FtsJ PF01728.14 EXF73671.1 - 0.045 13.7 0.0 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase Met_10 PF02475.11 EXF73671.1 - 0.051 13.1 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Ubie_methyltran PF01209.13 EXF73671.1 - 0.064 12.3 0.0 0.095 11.7 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EXF73671.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DUF4612 PF15389.1 EXF73673.1 - 0.19 12.3 9.4 0.55 10.8 6.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4612) AA_permease PF00324.16 EXF73674.1 - 2.7e-63 213.9 31.8 3.4e-63 213.6 22.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF73674.1 - 1.2e-16 60.2 36.8 2.6e-16 59.2 25.5 1.4 1 1 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 EXF73675.1 - 2e-82 276.8 30.7 2.6e-82 276.5 21.3 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein RNA_pol_L_2 PF13656.1 EXF73675.1 - 9.2e-22 76.2 0.3 1.5e-21 75.5 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EXF73675.1 - 1.3e-06 27.4 0.0 5.3e-06 25.4 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb3/Rpb11 dimerisation domain LSM PF01423.17 EXF73676.1 - 4.1e-18 64.6 0.1 6e-18 64.1 0.1 1.3 1 0 0 1 1 1 1 LSM domain DNA_pol_A_exo1 PF01612.15 EXF73677.1 - 2.3e-17 63.0 0.0 3.5e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease SMI1_KNR4 PF09346.5 EXF73678.1 - 7.1e-36 123.0 0.0 1.1e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) UPF0220 PF05255.6 EXF73680.1 - 4.5e-64 214.6 4.3 5.1e-64 214.5 3.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Pkinase PF00069.20 EXF73681.1 - 4.4e-63 212.8 0.0 5.8e-63 212.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF73681.1 - 3.2e-25 88.6 0.0 4.2e-25 88.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF73681.1 - 1.4e-07 30.8 0.0 6e-07 28.7 0.0 1.8 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 EXF73681.1 - 0.0046 16.7 0.1 0.018 14.8 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family MIF4G_like PF09088.6 EXF73682.1 - 5.8e-83 277.0 0.0 9.3e-83 276.3 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like_2 PF09090.6 EXF73682.1 - 5.3e-51 173.2 0.0 7.8e-51 172.7 0.0 1.3 1 0 0 1 1 1 1 MIF4G like WD40 PF00400.27 EXF73683.1 - 2.8e-27 93.5 9.9 3e-08 33.2 0.0 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.7 EXF73683.1 - 1.4e-19 69.8 0.3 2.5e-19 69.0 0.2 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 EXF73683.1 - 4.1e-06 25.2 3.4 0.0057 14.8 0.7 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 Sec8_exocyst PF04048.9 EXF73684.1 - 1.3e-47 160.9 1.4 2.6e-47 160.0 0.2 2.1 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain DUF2450 PF10475.4 EXF73684.1 - 3.3e-09 36.0 0.6 6.2e-09 35.1 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) RAI1 PF08652.6 EXF73685.1 - 1.3e-28 98.5 0.0 3.2e-28 97.2 0.0 1.7 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease Pkinase PF00069.20 EXF73686.1 - 1.3e-68 231.0 0.0 2e-68 230.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF73686.1 - 1.6e-48 165.0 0.0 2.5e-48 164.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF73686.1 - 3.4e-06 26.2 0.0 4.1e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Kinase-like ELYS PF13934.1 EXF73686.1 - 0.12 12.1 0.0 3.8 7.1 0.0 2.1 2 0 0 2 2 2 0 Nuclear pore complex assembly Transglut_core PF01841.14 EXF73687.1 - 9.1e-11 41.9 0.3 3e-10 40.3 0.2 1.9 1 0 0 1 1 1 1 Transglutaminase-like superfamily SH3_2 PF07653.12 EXF73687.1 - 1.1e-08 34.3 0.4 2.5e-08 33.2 0.3 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EXF73687.1 - 4.8e-05 22.6 2.2 6e-05 22.3 0.1 2.2 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EXF73687.1 - 0.00012 21.5 0.3 0.00026 20.4 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF410 PF04190.8 EXF73688.1 - 1.8e-46 158.8 0.0 2.1e-46 158.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Pro_dh PF01619.13 EXF73689.1 - 3.1e-37 128.2 0.0 3.4e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase Aldedh PF00171.17 EXF73690.1 - 3.7e-105 351.9 0.0 4.6e-105 351.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fungal_trans PF04082.13 EXF73691.1 - 4e-24 84.8 0.2 6.6e-24 84.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF73691.1 - 0.00035 20.4 12.0 0.00092 19.0 6.5 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_5 PF00266.14 EXF73692.1 - 2.2e-32 112.2 0.0 1.8e-21 76.3 0.0 2.0 1 1 1 2 2 2 2 Aminotransferase class-V adh_short PF00106.20 EXF73693.1 - 7.2e-08 32.5 0.0 1.2e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF73693.1 - 1.1e-06 28.5 0.0 1.6e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1777 PF08648.7 EXF73694.1 - 2.3e-21 76.3 51.4 2.3e-21 76.3 35.6 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 EXF73694.1 - 8.3 4.7 9.3 10 4.4 6.5 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Elong_Iki1 PF10483.4 EXF73695.1 - 1.3e-83 280.5 0.0 1.5e-83 280.3 0.0 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 NACHT PF05729.7 EXF73695.1 - 0.068 12.8 1.1 0.52 9.9 0.8 2.0 1 1 0 1 1 1 0 NACHT domain ASXH PF13919.1 EXF73696.1 - 6.9e-25 87.4 1.8 8.7e-25 87.1 0.0 2.0 2 0 0 2 2 2 1 Asx homology domain Longin PF13774.1 EXF73697.1 - 6.3e-23 80.1 0.9 5.5e-18 64.3 0.2 2.3 2 0 0 2 2 2 2 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EXF73697.1 - 3.6e-16 58.5 0.0 4.6e-15 54.9 0.0 2.1 2 0 0 2 2 2 1 Synaptobrevin DUF1664 PF07889.7 EXF73697.1 - 0.019 14.7 0.6 0.11 12.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) SIMPL PF04402.9 EXF73697.1 - 0.026 14.3 0.4 0.13 12.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF541) DUF4404 PF14357.1 EXF73697.1 - 0.61 10.5 8.1 0.92 9.9 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) HSCB_C PF07743.8 EXF73697.1 - 2.3 8.7 6.4 5.1 7.6 0.1 2.5 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain DUF664 PF04978.7 EXF73698.1 - 0.022 14.9 0.5 0.77 9.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF664) CLPTM1 PF05602.7 EXF73699.1 - 1.1e-149 498.9 0.0 1.4e-149 498.5 0.0 1.1 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) Lysine_decarbox PF03641.9 EXF73700.1 - 6.3e-31 106.9 0.1 1e-30 106.2 0.0 1.3 1 0 0 1 1 1 1 Possible lysine decarboxylase Proteasome PF00227.21 EXF73701.1 - 5.3e-49 166.0 0.1 6.8e-49 165.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EXF73701.1 - 6.6e-11 41.3 0.2 1.1e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Vps55 PF04133.9 EXF73702.1 - 3.1e-47 159.2 4.5 3.4e-47 159.0 3.1 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 PepSY_TM_1 PF13172.1 EXF73702.1 - 1.5 8.6 0.1 1.5 8.6 0.0 2.7 3 0 0 3 3 3 0 PepSY-associated TM helix Chorismate_bind PF00425.13 EXF73703.1 - 8.5e-65 218.6 0.0 1.6e-63 214.4 0.0 2.3 1 1 0 1 1 1 1 chorismate binding enzyme GATase PF00117.23 EXF73703.1 - 3.4e-25 88.6 0.0 1.1e-24 86.9 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.8 EXF73703.1 - 2e-13 50.5 0.0 5e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.8 EXF73703.1 - 6.2e-05 22.5 0.0 0.00021 20.8 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 TRAPPC9-Trs120 PF08626.6 EXF73704.1 - 1.4e-132 443.3 0.0 4.2e-120 402.0 0.0 2.1 2 0 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Glyco_hydro_63 PF03200.11 EXF73705.1 - 1.1e-238 794.1 0.2 9.9e-238 791.0 0.1 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EXF73705.1 - 4.7e-09 35.4 0.0 8.8e-09 34.5 0.0 1.3 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 EXF73705.1 - 0.0062 15.2 0.0 0.016 13.9 0.0 1.7 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase NOA36 PF06524.7 EXF73707.1 - 0.16 11.1 3.7 0.19 10.9 2.6 1.1 1 0 0 1 1 1 0 NOA36 protein TrmE_N PF10396.4 EXF73708.1 - 9.4e-35 119.0 0.0 2.2e-34 117.8 0.0 1.7 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus GTPase_Cys_C PF12631.2 EXF73708.1 - 1.7e-20 73.2 1.2 1.3e-19 70.3 0.0 2.5 2 0 0 2 2 2 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE MMR_HSR1 PF01926.18 EXF73708.1 - 4.3e-15 55.6 0.0 8.1e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EXF73708.1 - 6.5e-05 22.2 0.0 0.00017 20.8 0.0 1.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EXF73708.1 - 0.00039 20.2 0.0 0.00074 19.3 0.0 1.6 1 1 0 1 1 1 1 Dynamin family Miro PF08477.8 EXF73708.1 - 0.003 18.0 0.0 0.024 15.1 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 EXF73708.1 - 0.041 13.0 0.0 0.087 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_24 PF13479.1 EXF73708.1 - 0.2 11.2 0.0 0.34 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ribosomal_L28e PF01778.12 EXF73709.1 - 7.4e-31 106.9 1.0 1.5e-30 105.9 0.7 1.5 1 0 0 1 1 1 1 Ribosomal L28e protein family Mak16 PF04874.9 EXF73709.1 - 8.2e-22 77.1 45.2 1.2e-21 76.6 19.3 3.4 2 1 0 2 2 2 1 Mak16 protein C-terminal region TFIIF_alpha PF05793.7 EXF73709.1 - 0.007 14.7 31.0 0.0089 14.4 21.5 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.7 EXF73709.1 - 0.34 8.7 38.3 0.44 8.4 26.5 1.1 1 0 0 1 1 1 0 Nop14-like family Neur_chan_memb PF02932.11 EXF73709.1 - 1.2 8.9 4.4 2.5 7.9 3.0 1.7 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CDC45 PF02724.9 EXF73709.1 - 9.9 4.0 26.6 19 3.1 18.4 1.5 1 0 0 1 1 1 0 CDC45-like protein RabGAP-TBC PF00566.13 EXF73710.1 - 1.4e-35 122.7 4.2 3.2e-35 121.5 2.9 1.7 1 1 0 1 1 1 1 Rab-GTPase-TBC domain DUF3548 PF12068.3 EXF73710.1 - 2.2e-10 40.2 0.0 2.4e-05 23.7 0.0 3.5 3 0 0 3 3 3 3 Domain of unknown function (DUF3548) DUF2706 PF10913.3 EXF73711.1 - 0.13 11.9 0.4 0.21 11.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2706) HET PF06985.6 EXF73712.1 - 5.8e-23 81.5 0.0 1.1e-22 80.6 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UPF0029 PF01205.14 EXF73713.1 - 1.9e-30 104.8 0.0 2.7e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EXF73713.1 - 5.1e-07 29.5 0.0 1.2e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 RWD domain ACT_7 PF13840.1 EXF73714.1 - 2.3e-22 78.2 0.4 3e-19 68.3 0.1 2.4 2 0 0 2 2 2 2 ACT domain Methyltransf_32 PF13679.1 EXF73717.1 - 2.8e-18 65.9 0.0 6.4e-18 64.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Syntaxin-6_N PF09177.6 EXF73718.1 - 3.1e-24 85.2 0.0 9.3e-24 83.6 0.0 1.7 2 0 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EXF73718.1 - 8.7e-13 47.7 4.6 5.3e-12 45.2 0.7 2.9 3 0 0 3 3 3 1 SNARE domain DUF1470 PF07336.6 EXF73718.1 - 0.034 14.4 5.5 0.39 11.0 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1470) GLE1 PF07817.8 EXF73719.1 - 2.3e-23 82.4 0.0 2.6e-22 79.0 0.0 2.5 2 1 0 2 2 2 1 GLE1-like protein Oxysterol_BP PF01237.13 EXF73719.1 - 3.2 6.1 4.9 4.8 5.5 3.4 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein RNB PF00773.14 EXF73721.1 - 2.9e-78 263.4 0.0 6.7e-78 262.2 0.0 1.7 1 0 0 1 1 1 1 RNB domain DUF4239 PF14023.1 EXF73721.1 - 0.0021 17.4 0.3 0.0047 16.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4239) Ferritin_2 PF13668.1 EXF73722.1 - 5.9e-42 142.8 0.4 8.2e-42 142.3 0.3 1.2 1 0 0 1 1 1 1 Ferritin-like domain FAD_binding_3 PF01494.14 EXF73723.1 - 1.1e-42 146.3 0.0 1.7e-42 145.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EXF73723.1 - 7.5e-07 29.0 0.0 1.7e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF73723.1 - 1.1e-06 27.7 0.0 0.00024 20.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EXF73723.1 - 2.5e-05 24.5 0.0 8.8e-05 22.8 0.0 1.9 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF73723.1 - 0.00023 21.0 0.0 0.0013 18.6 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF73723.1 - 0.00026 20.1 0.0 0.00046 19.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EXF73723.1 - 0.00043 18.8 0.0 0.00069 18.1 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 EXF73723.1 - 0.0013 17.7 0.1 0.0026 16.7 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EXF73723.1 - 0.0038 16.1 0.0 0.0056 15.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EXF73723.1 - 0.0044 16.1 0.0 0.0075 15.3 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EXF73723.1 - 0.019 15.0 0.0 0.045 13.8 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SUKH_6 PF14568.1 EXF73723.1 - 0.021 15.2 0.1 0.045 14.2 0.1 1.5 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall Trp_halogenase PF04820.9 EXF73723.1 - 0.056 12.0 0.0 0.19 10.3 0.0 1.7 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EXF73723.1 - 0.071 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding ApbA PF02558.11 EXF73723.1 - 0.099 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EXF73723.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3217 PF11506.3 EXF73723.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3217) TrkA_N PF02254.13 EXF73723.1 - 0.19 11.7 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain GIDA PF01134.17 EXF73723.1 - 0.21 10.3 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 EXF73723.1 - 0.22 11.2 0.0 0.42 10.3 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF3433 PF11915.3 EXF73724.1 - 4.3e-43 145.3 13.1 2.1e-27 95.1 0.9 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) DUF3357 PF11837.3 EXF73724.1 - 1.5 8.6 4.0 0.67 9.8 0.0 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) PT PF04886.7 EXF73725.1 - 3.1 7.1 22.4 3.3 7.0 7.5 2.8 2 0 0 2 2 2 0 PT repeat AIG2 PF06094.7 EXF73726.1 - 1.2e-14 54.6 0.0 2e-14 53.9 0.0 1.4 1 1 0 1 1 1 1 AIG2-like family Gly-zipper_OmpA PF13436.1 EXF73726.1 - 0.048 13.3 7.8 0.1 12.2 5.4 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain FAT PF02259.18 EXF73727.1 - 2.9e-73 246.8 5.4 2.9e-73 246.8 3.8 2.1 2 0 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.22 EXF73727.1 - 1.7e-28 99.7 0.8 1.7e-26 93.1 0.2 3.1 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EXF73727.1 - 2.4e-09 36.4 0.2 7.9e-09 34.8 0.2 2.0 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 EXF73727.1 - 0.016 15.2 0.9 4.2 7.7 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat TPR_8 PF13181.1 EXF73727.1 - 0.018 14.8 4.5 0.48 10.3 0.3 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EXF73727.1 - 0.031 14.1 2.1 4.2 7.5 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EXF73727.1 - 0.45 10.1 8.0 17 5.1 0.1 3.8 3 0 0 3 3 3 0 TPR repeat TPR_1 PF00515.23 EXF73727.1 - 3 7.6 6.9 19 5.0 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Aminotran_1_2 PF00155.16 EXF73728.1 - 1.4e-07 30.7 0.0 1.9e-05 23.8 0.0 2.3 2 0 0 2 2 2 2 Aminotransferase class I and II Ribosomal_L4 PF00573.17 EXF73729.1 - 7.5e-37 126.5 0.8 1e-36 126.1 0.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EXF73729.1 - 1.3e-26 92.2 1.9 1.3e-26 92.2 1.3 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain AA_permease_2 PF13520.1 EXF73730.1 - 5.4e-43 147.1 36.4 7.4e-43 146.6 25.2 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF73730.1 - 9.8e-27 93.4 23.4 9.8e-27 93.4 16.2 2.2 2 0 0 2 2 2 2 Amino acid permease Glyco_hydro_76 PF03663.9 EXF73732.1 - 1e-151 505.5 16.0 1.2e-151 505.3 11.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EXF73732.1 - 0.019 13.9 6.3 0.7 8.8 0.2 3.0 3 0 0 3 3 3 0 Glycosyl Hydrolase Family 88 Dak1 PF02733.12 EXF73733.1 - 1.3e-111 372.3 6.0 1.6e-111 371.9 4.2 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EXF73733.1 - 6.5e-45 152.9 0.8 6.5e-45 152.9 0.6 2.0 2 0 0 2 2 2 1 DAK2 domain LRV PF01816.12 EXF73733.1 - 0.054 13.7 0.1 0.22 11.7 0.1 2.1 1 0 0 1 1 1 0 Leucine rich repeat variant LSM PF01423.17 EXF73734.1 - 5.6e-18 64.2 0.1 7.5e-18 63.8 0.1 1.2 1 0 0 1 1 1 1 LSM domain ECH_C PF13766.1 EXF73735.1 - 3.7e-35 120.6 0.1 1e-34 119.1 0.1 1.8 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EXF73735.1 - 4.4e-26 91.5 0.0 1.1e-24 86.9 0.0 2.2 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase family GATA PF00320.22 EXF73736.1 - 0.006 15.8 8.8 0.024 13.9 1.2 2.5 2 0 0 2 2 2 2 GATA zinc finger PAP_assoc PF03828.14 EXF73737.1 - 2.5e-12 46.5 0.0 4.5e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EXF73737.1 - 1.5e-05 25.1 0.0 3.4e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain DAD PF02109.11 EXF73737.1 - 0.0035 17.3 0.0 0.0076 16.2 0.0 1.5 1 0 0 1 1 1 1 DAD family DUF4604 PF15377.1 EXF73737.1 - 0.018 15.2 2.4 0.031 14.4 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Sugar_tr PF00083.19 EXF73738.1 - 1.1e-107 360.4 19.9 1.5e-107 360.0 13.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF73738.1 - 2.4e-21 75.8 23.7 2.4e-21 75.8 16.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.8 EXF73738.1 - 0.012 13.7 5.0 0.023 12.8 3.5 1.4 1 0 0 1 1 1 0 Transmembrane secretion effector SMI1_KNR4 PF09346.5 EXF73739.1 - 0.04 13.9 0.0 0.095 12.7 0.0 1.7 1 1 0 1 1 1 0 SMI1 / KNR4 family (SUKH-1) WSC PF01822.14 EXF73740.1 - 2.9e-15 55.9 9.8 6.2e-15 54.8 6.8 1.6 1 0 0 1 1 1 1 WSC domain DUF2244 PF10003.4 EXF73740.1 - 0.1 11.9 0.1 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) Glyco_hydro_43 PF04616.9 EXF73742.1 - 5.3e-58 196.3 4.7 1.1e-57 195.3 3.3 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 DUF3238 PF11579.3 EXF73742.1 - 0.029 13.9 0.0 0.047 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3238) Glyco_hydro_43 PF04616.9 EXF73743.1 - 2.3e-32 112.2 7.8 6.3e-32 110.7 2.9 2.7 2 1 0 2 2 2 1 Glycosyl hydrolases family 43 CBM_10 PF02013.11 EXF73743.1 - 0.22 11.8 1.7 1.1 9.5 1.2 2.2 1 0 0 1 1 1 0 Cellulose or protein binding domain Pacifastin_I PF05375.8 EXF73744.1 - 0.037 13.5 0.8 0.037 13.5 0.6 2.2 2 0 0 2 2 2 0 Pacifastin inhibitor (LCMII) Endothelin PF00322.12 EXF73744.1 - 0.72 9.1 3.5 9.5 5.5 0.3 2.5 2 0 0 2 2 2 0 Endothelin family NAD_binding_10 PF13460.1 EXF73745.1 - 4.5e-14 52.8 0.0 5.9e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EXF73745.1 - 2.8e-07 30.0 0.0 3.8e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EXF73745.1 - 0.00054 20.2 0.0 0.00085 19.6 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EXF73745.1 - 0.085 12.2 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EXF73745.1 - 0.17 10.5 0.0 0.22 10.2 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.11 EXF73746.1 - 3.4e-22 78.6 68.0 2.3e-13 49.5 25.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EXF73746.1 - 1.1e-06 27.3 14.0 1.1e-06 27.3 9.7 2.6 2 1 1 3 3 3 2 MFS/sugar transport protein MFS_1 PF07690.11 EXF73747.1 - 2.6e-36 125.0 29.3 2.6e-36 125.0 20.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily SpoVAB PF13782.1 EXF73747.1 - 0.0018 18.2 1.0 0.0065 16.4 0.4 2.1 2 0 0 2 2 2 1 Stage V sporulation protein AB CBM_4_9 PF02018.12 EXF73749.1 - 0.0006 19.8 0.0 0.0013 18.7 0.0 1.5 1 1 0 1 1 1 1 Carbohydrate binding domain MAM PF00629.18 EXF73749.1 - 0.059 13.1 0.0 0.083 12.6 0.0 1.2 1 0 0 1 1 1 0 MAM domain TALPID3 PF15324.1 EXF73749.1 - 0.51 7.6 3.1 0.68 7.2 2.1 1.2 1 0 0 1 1 1 0 Hedgehog signalling target Peptidase_M43 PF05572.8 EXF73750.1 - 7.2e-13 48.4 0.0 1.6e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EXF73750.1 - 4.6e-05 23.4 0.1 0.00013 21.9 0.0 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EXF73750.1 - 0.0036 17.8 0.2 0.0068 16.9 0.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EXF73750.1 - 0.016 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Matrixin Astacin PF01400.19 EXF73750.1 - 0.023 14.1 0.0 0.039 13.3 0.0 1.3 1 0 0 1 1 1 0 Astacin (Peptidase family M12A) Reprolysin_2 PF13574.1 EXF73750.1 - 0.024 14.6 1.3 0.045 13.7 0.8 1.5 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EXF73750.1 - 0.089 11.6 0.9 0.13 11.0 0.6 1.2 1 0 0 1 1 1 0 Peptidase M66 Reprolysin_4 PF13583.1 EXF73750.1 - 0.09 12.2 0.1 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like RGS PF00615.14 EXF73751.1 - 3e-05 24.0 0.0 0.00028 20.9 0.0 2.1 2 0 0 2 2 2 1 Regulator of G protein signaling domain Abhydrolase_6 PF12697.2 EXF73752.1 - 7.2e-16 58.7 0.1 1.2e-15 58.0 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF73752.1 - 9.3e-06 25.4 0.3 2.1e-05 24.3 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family FbpA PF05833.6 EXF73753.1 - 0.00065 18.3 1.4 0.00083 18.0 0.9 1.2 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) Herpes_UL3 PF03369.8 EXF73753.1 - 0.45 10.4 3.3 2 8.4 1.4 2.2 2 0 0 2 2 2 0 Herpesvirus UL3 protein Rotamase_2 PF13145.1 EXF73753.1 - 1.1 9.8 10.5 0.55 10.8 5.2 2.0 1 1 1 2 2 2 0 PPIC-type PPIASE domain MFS_1 PF07690.11 EXF73754.1 - 9.9e-35 119.8 59.4 7.3e-29 100.5 24.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EXF73754.1 - 1.3e-11 43.5 33.8 4.8e-11 41.7 9.8 2.0 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.2 EXF73754.1 - 0.0031 17.2 8.3 0.011 15.5 0.7 3.0 3 0 0 3 3 3 2 MFS_1 like family Radial_spoke_3 PF06098.6 EXF73755.1 - 0.042 12.8 13.1 0.053 12.5 9.1 1.1 1 0 0 1 1 1 0 Radial spoke protein 3 HSP70 PF00012.15 EXF73755.1 - 0.26 9.1 7.5 0.28 9.0 5.2 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF3449 PF11931.3 EXF73755.1 - 1.5 8.3 11.1 2 7.9 7.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) DUF3987 PF13148.1 EXF73755.1 - 2 6.8 15.2 2.6 6.5 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF2514 PF10721.4 EXF73755.1 - 2.3 7.9 15.9 3.1 7.4 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) AAA_23 PF13476.1 EXF73755.1 - 2.7 8.2 6.8 3.5 7.8 4.7 1.2 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 EXF73755.1 - 4.3 6.2 8.8 4.9 6.0 6.1 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EXF73755.1 - 4.8 6.1 11.5 6.2 5.7 8.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Med9 PF07544.8 EXF73758.1 - 0.0042 16.7 5.7 0.45 10.2 0.9 3.1 3 0 0 3 3 3 2 RNA polymerase II transcription mediator complex subunit 9 DivIC PF04977.10 EXF73758.1 - 0.0044 16.4 3.6 0.0044 16.4 2.5 2.1 2 0 0 2 2 2 1 Septum formation initiator SlyX PF04102.7 EXF73758.1 - 0.016 15.5 5.4 0.02 15.2 0.6 2.6 2 1 0 2 2 2 0 SlyX DUF904 PF06005.7 EXF73758.1 - 0.049 13.9 5.7 0.76 10.1 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF904) TraC PF07820.7 EXF73758.1 - 1.3 9.2 6.3 7.6 6.7 0.0 2.9 2 1 0 3 3 3 0 TraC-like protein Fib_alpha PF08702.5 EXF73758.1 - 1.6 8.8 7.2 1.7 8.7 0.4 2.4 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family NYD-SP28_assoc PF14775.1 EXF73761.1 - 0.03 14.0 1.9 0.13 12.0 1.0 2.2 1 1 0 1 1 1 0 Sperm tail C-terminal domain Shugoshin_N PF07558.6 EXF73761.1 - 0.037 13.7 1.6 0.086 12.5 1.1 1.7 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region IncA PF04156.9 EXF73761.1 - 0.054 13.0 4.4 0.082 12.4 3.0 1.3 1 0 0 1 1 1 0 IncA protein HALZ PF02183.13 EXF73761.1 - 0.06 13.0 0.6 0.19 11.4 0.4 1.9 1 0 0 1 1 1 0 Homeobox associated leucine zipper Tnp_P_element PF12017.3 EXF73761.1 - 0.062 12.5 0.7 0.1 11.7 0.5 1.4 1 0 0 1 1 1 0 Transposase protein CCDC155 PF14662.1 EXF73761.1 - 0.065 12.8 6.3 0.11 12.0 4.4 1.4 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 Ftsk_gamma PF09397.5 EXF73761.1 - 0.079 12.6 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 Ftsk gamma domain Mto2_bdg PF12808.2 EXF73761.1 - 0.079 13.0 4.9 0.19 11.8 0.6 2.8 2 1 1 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region ThiS-like PF14453.1 EXF73761.1 - 0.081 12.7 0.3 0.2 11.5 0.0 1.8 2 0 0 2 2 2 0 ThiS-like ubiquitin BLOC1_2 PF10046.4 EXF73761.1 - 0.15 12.2 4.5 0.19 11.8 1.8 2.0 2 1 1 3 3 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4584 PF15223.1 EXF73761.1 - 0.34 10.1 3.3 0.38 9.9 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4584) Phlebovirus_NSM PF07246.6 EXF73761.1 - 0.35 9.9 8.0 0.28 10.3 4.8 1.3 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M TMF_TATA_bd PF12325.3 EXF73761.1 - 0.47 10.1 7.6 0.21 11.3 3.7 1.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding UPF0449 PF15136.1 EXF73761.1 - 0.59 10.3 3.5 1.4 9.2 2.1 1.8 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF972 PF06156.8 EXF73761.1 - 1.2 9.4 8.4 0.81 10.0 2.5 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF972) Elongin_A PF06881.6 EXF73761.1 - 2.1 8.7 6.8 1.1 9.6 1.3 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A bZIP_2 PF07716.10 EXF73761.1 - 3.1 7.6 9.2 0.34 10.7 0.9 2.4 2 0 0 2 2 2 0 Basic region leucine zipper DivIC PF04977.10 EXF73761.1 - 4.6 6.7 10.7 0.14 11.6 1.1 2.6 2 1 1 3 3 3 0 Septum formation initiator MIP PF00230.15 EXF73762.1 - 3e-48 164.2 15.0 3.7e-48 163.9 10.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein AMP-binding PF00501.23 EXF73763.1 - 3.8e-65 219.8 0.1 5.3e-65 219.4 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EXF73763.1 - 1e-08 35.9 0.2 3.2e-08 34.3 0.2 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DIOX_N PF14226.1 EXF73764.1 - 1.3e-21 77.2 0.0 2e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EXF73764.1 - 0.019 15.2 0.0 0.033 14.4 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily FTA4 PF13093.1 EXF73765.1 - 0.016 14.6 1.5 0.029 13.7 0.6 1.6 1 1 1 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Sec34 PF04136.10 EXF73765.1 - 0.062 12.9 0.8 0.14 11.8 0.2 1.8 2 0 0 2 2 2 0 Sec34-like family IncA PF04156.9 EXF73765.1 - 0.11 12.1 1.0 0.14 11.6 0.7 1.3 1 0 0 1 1 1 0 IncA protein Osmo_CC PF08946.5 EXF73765.1 - 0.16 11.9 1.1 1.1 9.3 0.3 2.5 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Prefoldin_3 PF13758.1 EXF73765.1 - 0.2 11.4 1.9 0.27 11.0 0.3 2.0 2 1 0 2 2 2 0 Prefoldin subunit Syntaxin-6_N PF09177.6 EXF73765.1 - 0.32 11.4 2.2 0.66 10.4 0.6 2.3 1 1 3 4 4 4 0 Syntaxin 6, N-terminal DUF4200 PF13863.1 EXF73765.1 - 0.97 9.3 8.6 0.95 9.4 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Ank_2 PF12796.2 EXF73767.1 - 2.2e-24 85.6 2.3 1.5e-06 28.4 0.0 6.5 2 1 4 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 EXF73767.1 - 2.4e-17 61.7 1.4 0.051 13.4 0.0 8.5 8 1 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.1 EXF73767.1 - 1.2e-12 48.0 0.1 0.063 13.8 0.0 6.7 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF73767.1 - 5.3e-12 44.7 6.1 0.15 12.3 0.0 9.0 11 0 0 11 11 11 3 Ankyrin repeat Ank_5 PF13857.1 EXF73767.1 - 2.4e-10 40.3 1.1 2.1 8.7 0.0 7.0 7 0 0 7 7 7 3 Ankyrin repeats (many copies) F-box-like PF12937.2 EXF73767.1 - 0.0082 15.8 1.5 3.2 7.5 0.0 3.5 3 0 0 3 3 3 1 F-box-like Zn_clus PF00172.13 EXF73768.1 - 0.00029 20.6 2.3 0.00029 20.6 1.6 2.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF73768.1 - 0.0031 16.1 0.3 0.015 13.9 0.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EXF73769.1 - 1.7e-38 132.2 27.8 1.7e-38 132.2 19.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Cytochrom_B562 PF07361.6 EXF73770.1 - 0.06 13.7 2.9 0.22 11.9 1.8 2.0 2 0 0 2 2 2 0 Cytochrome b562 Rootletin PF15035.1 EXF73770.1 - 0.41 10.6 11.3 1.6 8.6 7.1 2.0 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion DUF607 PF04678.8 EXF73770.1 - 0.48 10.3 2.2 2 8.2 2.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF607 V_ATPase_I PF01496.14 EXF73770.1 - 7.6 4.2 7.8 2 6.1 3.5 1.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Herpes_BLRF2 PF05812.7 EXF73771.1 - 0.073 12.8 1.8 0.11 12.3 1.2 1.3 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Aminotran_1_2 PF00155.16 EXF73773.1 - 4.8e-51 173.8 0.0 5.9e-51 173.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EXF73773.1 - 0.078 12.1 0.0 0.12 11.4 0.0 1.3 1 1 0 1 1 1 0 Beta-eliminating lyase p450 PF00067.17 EXF73774.1 - 4.6e-35 121.0 0.0 5.3e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ApbA_C PF08546.6 EXF73774.1 - 0.0021 18.0 0.0 0.0043 17.0 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal Condensation PF00668.15 EXF73776.1 - 0.0027 16.6 0.2 0.059 12.2 0.0 2.2 2 0 0 2 2 2 2 Condensation domain AA_permease PF00324.16 EXF73777.1 - 3.8e-145 483.8 38.2 4.4e-145 483.6 26.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF73777.1 - 1.7e-39 135.5 41.1 2.5e-39 135.0 28.2 1.4 1 1 0 1 1 1 1 Amino acid permease Ank_2 PF12796.2 EXF73778.1 - 1.6e-52 175.7 0.1 3.5e-11 43.2 0.1 8.4 3 2 2 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 EXF73778.1 - 5.4e-42 139.5 0.1 2.5e-06 27.0 0.0 13.3 14 0 0 14 14 14 9 Ankyrin repeat Ank_4 PF13637.1 EXF73778.1 - 3.8e-41 138.7 3.8 4.2e-08 33.4 0.0 10.9 7 5 5 13 13 13 8 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF73778.1 - 1.8e-39 132.8 1.5 2.2e-06 27.7 0.0 11.9 7 4 5 12 12 12 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF73778.1 - 6.8e-30 100.1 0.6 0.038 14.2 0.0 12.5 13 0 0 13 13 13 7 Ankyrin repeat SPRY PF00622.23 EXF73778.1 - 0.00077 19.5 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 SPRY domain Peptidase_M35 PF02102.10 EXF73779.1 - 0.018 13.6 4.3 0.026 13.1 3.0 1.1 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family Golgin_A5 PF09787.4 EXF73779.1 - 2.1 6.7 5.4 3.2 6.1 3.7 1.3 1 0 0 1 1 1 0 Golgin subfamily A member 5 AAA PF00004.24 EXF73780.1 - 5.4e-13 49.2 0.0 4.6e-12 46.2 0.0 2.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EXF73780.1 - 5.8e-05 23.2 0.5 0.00057 20.0 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EXF73780.1 - 0.0001 22.3 0.0 0.00021 21.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EXF73780.1 - 0.0017 18.0 0.0 0.0036 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EXF73780.1 - 0.0043 16.1 0.0 0.0074 15.3 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EXF73780.1 - 0.012 15.3 0.1 0.026 14.2 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 EXF73780.1 - 0.024 15.4 0.0 0.079 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EXF73780.1 - 0.066 13.0 0.0 0.13 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EXF73780.1 - 0.087 11.6 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Chitin_bind_3 PF03067.10 EXF73783.1 - 1.5e-09 38.3 0.0 1.9e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Chitin binding domain Glyco_hydro_61 PF03443.9 EXF73783.1 - 0.016 15.0 0.1 0.16 11.7 0.1 2.1 1 1 0 1 1 1 0 Glycosyl hydrolase family 61 Fungal_trans PF04082.13 EXF73784.1 - 1.1e-26 93.3 0.0 1.9e-26 92.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF73784.1 - 9.4e-06 25.4 11.4 1.8e-05 24.5 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EXF73784.1 - 4.9 7.3 11.4 22 5.3 7.9 2.0 1 1 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region PAN_4 PF14295.1 EXF73785.1 - 0.02 14.5 3.8 0.15 11.8 0.4 2.7 2 0 0 2 2 2 0 PAN domain Sugar_tr PF00083.19 EXF73786.1 - 2.1e-116 389.1 23.4 8.1e-115 383.9 16.2 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF73786.1 - 2.5e-25 88.9 43.7 6.9e-18 64.4 10.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BT1 PF03092.11 EXF73786.1 - 0.0018 17.0 3.1 0.0021 16.8 1.1 1.7 1 1 0 1 1 1 1 BT1 family THF_DHG_CYH PF00763.18 EXF73787.1 - 1.1e-21 77.0 0.0 2e-21 76.1 0.0 1.5 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EXF73787.1 - 0.00027 20.0 0.2 0.00039 19.5 0.2 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ABC2_membrane PF01061.19 EXF73788.1 - 1.1e-86 289.4 62.1 1.9e-45 154.6 12.9 3.3 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EXF73788.1 - 8.2e-39 133.0 0.0 7.7e-21 74.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EXF73788.1 - 1.3e-28 98.6 5.5 3.8e-25 87.5 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 EXF73788.1 - 3.3e-11 42.8 35.0 5.2e-09 35.5 5.2 2.5 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_22 PF13401.1 EXF73788.1 - 1.5e-07 31.6 0.1 0.05 13.7 0.0 3.3 2 1 0 2 2 2 2 AAA domain cobW PF02492.14 EXF73788.1 - 2.6e-06 27.0 0.6 6.4e-05 22.4 0.4 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.1 EXF73788.1 - 9.4e-06 26.4 0.0 0.057 14.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain ABC_trans_N PF14510.1 EXF73788.1 - 1.4e-05 25.0 0.0 6.2e-05 23.0 0.0 2.1 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_29 PF13555.1 EXF73788.1 - 1.6e-05 24.3 0.5 0.066 12.7 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EXF73788.1 - 2e-05 23.8 0.0 0.00068 18.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 UPF0079 PF02367.12 EXF73788.1 - 5.8e-05 22.7 0.6 0.027 14.0 0.2 2.7 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_21 PF13304.1 EXF73788.1 - 9.5e-05 22.5 0.0 0.65 9.8 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EXF73788.1 - 0.00034 20.5 0.3 0.11 12.3 0.0 2.7 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 EXF73788.1 - 0.0005 20.0 0.1 0.43 10.5 0.1 2.7 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_18 PF13238.1 EXF73788.1 - 0.00053 20.2 0.0 0.11 12.8 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.1 EXF73788.1 - 0.00072 19.5 0.2 0.038 13.9 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 EXF73788.1 - 0.00092 18.6 0.0 1 8.7 0.1 3.1 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 EXF73788.1 - 0.00094 18.7 0.7 0.97 8.8 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_19 PF13245.1 EXF73788.1 - 0.00096 18.8 0.1 1.7 8.4 0.1 2.7 2 0 0 2 2 2 2 Part of AAA domain NACHT PF05729.7 EXF73788.1 - 0.0013 18.4 0.2 0.28 10.8 0.3 2.5 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EXF73788.1 - 0.0015 18.5 2.8 0.15 12.0 0.5 3.0 3 1 0 3 3 2 1 AAA ATPase domain AAA_10 PF12846.2 EXF73788.1 - 0.0021 17.5 0.1 1.7 8.0 0.3 2.4 2 0 0 2 2 2 2 AAA-like domain SMC_N PF02463.14 EXF73788.1 - 0.0027 16.9 0.0 0.45 9.7 0.0 3.2 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain Arch_ATPase PF01637.13 EXF73788.1 - 0.0042 16.7 0.0 3.7 7.1 0.0 2.4 2 0 0 2 2 2 1 Archaeal ATPase AAA PF00004.24 EXF73788.1 - 0.007 16.5 0.0 2.6 8.2 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EXF73788.1 - 0.0095 14.8 1.3 0.57 8.9 0.3 2.4 2 0 0 2 2 2 1 NB-ARC domain Miro PF08477.8 EXF73788.1 - 0.011 16.2 0.0 1.2 9.6 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein T2SE PF00437.15 EXF73788.1 - 0.022 13.6 0.1 3.6 6.4 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein PduV-EutP PF10662.4 EXF73788.1 - 0.028 13.9 0.2 0.44 10.0 0.3 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 EXF73788.1 - 0.029 13.9 0.3 2.1 7.8 0.2 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EXF73788.1 - 0.065 12.3 0.1 0.58 9.2 0.2 2.1 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.10 EXF73788.1 - 0.085 12.5 0.0 8.2 6.1 0.1 3.0 3 0 0 3 3 3 0 NTPase SbcCD_C PF13558.1 EXF73788.1 - 0.15 12.0 0.0 2.6 8.0 0.0 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Septin PF00735.13 EXF73788.1 - 0.16 10.9 0.0 1.4 7.8 0.1 2.1 2 0 0 2 2 2 0 Septin ArgK PF03308.11 EXF73788.1 - 0.23 10.2 0.7 25 3.5 0.1 2.9 3 0 0 3 3 3 0 ArgK protein AAA_15 PF13175.1 EXF73788.1 - 0.25 10.3 0.0 4.8 6.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.1 EXF73788.1 - 0.36 11.1 0.3 4.7 7.4 0.1 2.4 2 0 0 2 2 2 0 AAA domain DUF4291 PF14124.1 EXF73789.1 - 5.5e-60 202.0 0.0 1e-59 201.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Git3 PF11710.3 EXF73789.1 - 1.1e-16 60.9 8.7 1.1e-16 60.9 6.0 1.6 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 EXF73789.1 - 1.2e-07 31.1 8.5 1.2e-07 31.1 5.9 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 EXF73789.1 - 0.036 12.9 10.8 0.04 12.8 5.3 2.2 2 0 0 2 2 2 0 Slime mold cyclic AMP receptor YjgP_YjgQ PF03739.9 EXF73789.1 - 0.043 12.5 0.2 0.043 12.5 0.1 2.5 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family AMP-binding PF00501.23 EXF73790.1 - 3.5e-78 262.8 0.0 4.9e-78 262.3 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EXF73790.1 - 7.8e-66 221.5 0.0 1.1e-65 221.0 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EXF73790.1 - 5.5e-13 48.9 0.0 1.1e-12 47.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EXF73790.1 - 1e-10 41.6 0.0 2.8e-10 40.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EXF73790.1 - 7.8e-08 31.3 0.0 1.7e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 EXF73790.1 - 4.1e-07 30.8 0.0 2.8e-06 28.1 0.0 2.6 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.10 EXF73790.1 - 0.0024 16.8 0.0 0.011 14.6 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EXF73790.1 - 0.0077 16.1 0.0 0.019 14.8 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EXF73790.1 - 0.034 13.0 1.1 0.66 8.8 0.7 2.6 1 1 0 1 1 1 0 RmlD substrate binding domain MFS_1 PF07690.11 EXF73791.1 - 9.5e-15 54.1 48.5 3.6e-08 32.5 26.6 3.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_S8 PF00082.17 EXF73792.1 - 3.2e-39 134.7 0.0 5.7e-39 133.9 0.0 1.4 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EXF73792.1 - 2.9e-06 27.6 0.0 6.9e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Pox_F15 PF04596.7 EXF73792.1 - 0.12 12.0 0.1 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Poxvirus protein F15 DUF3632 PF12311.3 EXF73793.1 - 7.7e-34 117.1 0.0 1.2e-33 116.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Cytochrom_C_2 PF01322.15 EXF73793.1 - 0.066 13.7 0.1 0.27 11.7 0.0 2.1 2 0 0 2 2 2 0 Cytochrome C' Ribonuclease PF00545.15 EXF73794.1 - 5e-05 23.2 0.2 7.1e-05 22.7 0.1 1.4 1 1 0 1 1 1 1 ribonuclease DUF1700 PF08006.6 EXF73795.1 - 2 7.7 5.2 0.57 9.4 1.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1700) p450 PF00067.17 EXF73796.1 - 6.9e-54 183.0 0.0 8.4e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Flocculin_t3 PF13928.1 EXF73797.1 - 0.044 13.9 2.5 0.044 13.9 1.7 4.4 4 0 0 4 4 4 0 Flocculin type 3 repeat Methyltransf_32 PF13679.1 EXF73798.1 - 7.4e-24 84.0 0.1 1.1e-23 83.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF73798.1 - 1.9e-07 30.7 0.0 3.4e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF73798.1 - 2.7e-06 27.9 0.0 5.1e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF73798.1 - 4.9e-06 26.0 0.0 8.7e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain GidB PF02527.10 EXF73798.1 - 0.00017 20.7 0.0 0.00029 20.0 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_4 PF02390.12 EXF73798.1 - 0.0032 16.5 0.0 0.0052 15.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 EXF73798.1 - 0.0077 16.6 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF73798.1 - 0.0093 16.4 0.0 0.021 15.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EXF73798.1 - 0.016 14.3 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EXF73798.1 - 0.068 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ank_2 PF12796.2 EXF73799.1 - 1e-78 259.7 10.5 1.3e-16 60.7 0.1 8.9 4 3 6 10 10 10 9 Ankyrin repeats (3 copies) Ank PF00023.25 EXF73799.1 - 1.3e-60 198.3 24.8 8.7e-05 22.1 0.1 17.6 18 0 0 18 18 18 15 Ankyrin repeat Ank_4 PF13637.1 EXF73799.1 - 3.7e-54 180.2 16.7 6.3e-07 29.7 0.0 14.3 7 3 8 15 15 15 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF73799.1 - 3.3e-45 147.5 9.2 0.0001 22.1 0.0 17.2 17 0 0 17 17 17 8 Ankyrin repeat Ank_5 PF13857.1 EXF73799.1 - 2.2e-34 116.6 21.4 6.1e-06 26.3 0.2 13.6 10 3 5 15 15 15 7 Ankyrin repeats (many copies) NACHT PF05729.7 EXF73799.1 - 1.1e-13 51.1 0.0 3.6e-13 49.4 0.0 1.9 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EXF73799.1 - 0.053 13.6 0.0 0.23 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF1843 PF08898.5 EXF73799.1 - 0.074 13.1 12.9 0.38 10.8 0.3 5.1 5 1 1 6 6 6 0 Domain of unknown function (DUF1843) MAGE_N PF12440.3 EXF73799.1 - 0.087 13.1 9.7 0.19 12.0 6.8 1.6 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal WEMBL PF05701.6 EXF73799.1 - 0.49 8.8 2.5 0.72 8.2 1.7 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Fungal_trans_2 PF11951.3 EXF73800.1 - 5.5e-09 35.0 0.0 7.1e-09 34.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF73800.1 - 3.5e-06 26.8 9.9 5.6e-06 26.1 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 EXF73801.1 - 1.9e-50 171.7 0.0 2.7e-50 171.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_10 PF00331.15 EXF73803.1 - 7.5e-99 330.7 0.0 8.7e-99 330.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 EXF73803.1 - 5.8e-15 54.6 11.0 1.6e-14 53.2 7.7 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain Botulinum_HA-17 PF05588.6 EXF73803.1 - 1.1 9.1 3.8 5.4 6.9 0.3 2.3 1 1 0 2 2 2 0 Clostridium botulinum HA-17 protein ADH_N PF08240.7 EXF73804.1 - 1e-24 86.3 4.8 1.9e-24 85.4 3.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF73804.1 - 1.5e-20 73.0 0.0 2.4e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF73804.1 - 2.6e-10 41.2 0.0 5.5e-10 40.2 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EXF73804.1 - 0.00063 18.9 0.1 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EXF73804.1 - 0.043 13.9 0.0 0.082 13.0 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase CBM_10 PF02013.11 EXF73804.1 - 1.7 8.9 6.2 5.7 7.2 0.1 2.7 3 0 0 3 3 3 0 Cellulose or protein binding domain Peroxidase_2 PF01328.12 EXF73805.1 - 4.5e-10 38.7 0.2 4.5e-09 35.4 0.1 2.0 1 1 0 1 1 1 1 Peroxidase, family 2 CFEM PF05730.6 EXF73806.1 - 8e-12 44.8 10.3 1.3e-11 44.1 7.1 1.3 1 0 0 1 1 1 1 CFEM domain CcmH PF03918.9 EXF73806.1 - 0.071 12.0 0.1 0.19 10.7 0.0 1.7 1 0 0 1 1 1 0 Cytochrome C biogenesis protein GMC_oxred_C PF05199.8 EXF73807.1 - 1e-27 97.2 0.0 1.7e-27 96.5 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EXF73807.1 - 7.9e-24 84.3 0.0 9e-22 77.5 0.0 2.8 2 1 0 2 2 2 1 GMC oxidoreductase Pyr_redox_3 PF13738.1 EXF73807.1 - 2.5e-05 24.4 0.0 0.00036 20.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF73807.1 - 0.00074 19.4 0.0 0.0021 18.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF73807.1 - 0.0013 17.7 0.3 0.26 10.1 0.2 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF73807.1 - 0.01 14.7 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_8 PF13450.1 EXF73807.1 - 0.012 15.5 0.0 0.027 14.4 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EXF73807.1 - 0.14 10.9 0.6 0.23 10.2 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain Glyco_hydro_3 PF00933.16 EXF73808.1 - 1e-83 280.7 0.0 1.5e-83 280.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF73808.1 - 1.9e-53 181.2 0.1 3e-53 180.6 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF73808.1 - 2.3e-23 81.8 0.0 4.6e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain NYD-SP28_assoc PF14775.1 EXF73809.1 - 0.045 13.4 0.0 0.077 12.6 0.0 1.3 1 0 0 1 1 1 0 Sperm tail C-terminal domain UbiA PF01040.13 EXF73810.1 - 1.2e-15 57.4 9.7 2.1e-15 56.6 6.7 1.4 1 0 0 1 1 1 1 UbiA prenyltransferase family Nuc_sug_transp PF04142.10 EXF73811.1 - 9.8e-12 44.4 5.0 1.6e-11 43.8 3.4 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter NMN_transporter PF04973.7 EXF73811.1 - 0.0029 17.1 3.8 0.0065 15.9 2.6 1.6 1 0 0 1 1 1 1 Nicotinamide mononucleotide transporter Abhydrolase_3 PF07859.8 EXF73813.1 - 6.2e-42 143.5 0.0 1.2e-41 142.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EXF73813.1 - 3.6e-08 32.5 0.5 8.5e-08 31.3 0.3 1.4 1 1 0 1 1 1 1 Carboxylesterase family Prok-RING_1 PF14446.1 EXF73814.1 - 0.0046 16.6 9.5 0.2 11.4 0.1 2.2 1 1 1 2 2 2 2 Prokaryotic RING finger family 1 PHD PF00628.24 EXF73814.1 - 0.04 13.6 9.1 0.089 12.5 2.7 2.2 2 0 0 2 2 2 0 PHD-finger zf-ribbon_3 PF13248.1 EXF73814.1 - 0.12 11.6 0.3 0.12 11.6 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Baculo_ME53 PF06061.6 EXF73814.1 - 0.12 11.3 6.3 0.14 11.1 4.4 1.0 1 0 0 1 1 1 0 Baculoviridae ME53 zf-RING_3 PF14369.1 EXF73814.1 - 0.17 11.9 0.7 0.17 11.9 0.5 2.4 2 0 0 2 2 2 0 zinc-finger C1_1 PF00130.17 EXF73814.1 - 0.21 11.3 11.6 14 5.5 8.0 2.2 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Desulfoferrod_N PF06397.7 EXF73814.1 - 0.42 10.0 3.7 8.4 5.8 0.3 2.3 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Sgf11 PF08209.6 EXF73814.1 - 2.4 7.5 10.9 0.32 10.3 0.6 3.0 2 1 1 3 3 3 0 Sgf11 (transcriptional regulation protein) DNA_RNApol_7kD PF03604.8 EXF73814.1 - 7.1 6.1 9.4 1.5 8.3 1.1 2.8 1 1 2 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Lipase_GDSL PF00657.17 EXF73815.1 - 1.4e-09 38.1 1.1 2.1e-09 37.5 0.5 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EXF73815.1 - 6.3e-09 36.2 0.3 9e-09 35.7 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF3818 PF12825.2 EXF73816.1 - 3.1e-38 131.3 0.0 4.7e-25 88.0 0.0 2.1 1 1 1 2 2 2 2 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EXF73816.1 - 3.2e-32 111.0 0.0 5.3e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 PX-associated Cation_efflux PF01545.16 EXF73817.1 - 5.5e-30 104.4 4.3 7.5e-30 103.9 3.0 1.1 1 0 0 1 1 1 1 Cation efflux family Pkinase PF00069.20 EXF73818.1 - 1.6e-22 79.9 0.0 2.9e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF73818.1 - 3.8e-17 62.2 0.0 8.2e-16 57.8 0.0 2.7 2 1 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EXF73818.1 - 0.076 11.8 0.1 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase CorA PF01544.13 EXF73819.1 - 7.9e-07 28.3 9.9 8.7e-07 28.2 4.7 2.4 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein DUF912 PF06024.7 EXF73819.1 - 0.0017 18.3 0.0 0.0044 17.0 0.0 1.6 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) UPF0193 PF05250.6 EXF73819.1 - 0.032 13.8 0.0 0.62 9.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0193) TRIQK PF15168.1 EXF73819.1 - 0.12 12.3 0.7 3.3 7.6 0.0 2.3 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family TPR_11 PF13414.1 EXF73820.1 - 7.2e-07 28.7 1.3 7.2e-07 28.7 0.9 4.1 4 0 0 4 4 4 1 TPR repeat AAA_16 PF13191.1 EXF73820.1 - 1.9e-06 27.9 0.6 6.4e-05 23.0 0.0 3.8 5 0 0 5 5 5 1 AAA ATPase domain TPR_16 PF13432.1 EXF73820.1 - 0.0001 22.8 4.9 0.0016 19.0 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EXF73820.1 - 0.00017 21.2 9.5 0.018 14.8 0.3 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EXF73820.1 - 0.00033 20.5 8.2 0.0011 18.8 1.0 4.4 3 1 2 5 5 5 2 Tetratricopeptide repeat AAA_22 PF13401.1 EXF73820.1 - 0.0004 20.5 2.1 0.013 15.6 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_26 PF13500.1 EXF73820.1 - 0.00058 19.5 0.0 0.0017 18.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain TPR_1 PF00515.23 EXF73820.1 - 0.00077 18.9 5.1 0.061 12.9 0.2 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EXF73820.1 - 0.0011 19.2 16.5 0.09 13.1 0.2 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat Arch_ATPase PF01637.13 EXF73820.1 - 0.0012 18.6 0.0 0.0054 16.4 0.0 2.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_28 PF13521.1 EXF73820.1 - 0.0038 17.1 0.1 0.018 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain TPR_14 PF13428.1 EXF73820.1 - 0.012 16.1 11.8 18 6.3 0.0 6.8 6 1 1 7 7 6 0 Tetratricopeptide repeat DUF3135 PF11333.3 EXF73820.1 - 0.027 14.6 1.3 0.13 12.4 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3135) NACHT PF05729.7 EXF73820.1 - 0.033 13.8 0.0 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain TPR_17 PF13431.1 EXF73820.1 - 0.91 9.8 6.8 0.14 12.4 0.2 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EXF73820.1 - 1.5 8.7 8.1 3.9 7.4 0.2 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Glyco_hydro_53 PF07745.8 EXF73821.1 - 3.2e-86 289.1 0.1 3.7e-86 288.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 LysM PF01476.15 EXF73822.1 - 1.2e-10 41.1 1.8 0.068 13.0 0.0 4.8 5 0 0 5 5 5 4 LysM domain HSDR_N_2 PF13588.1 EXF73822.1 - 5e-06 26.2 0.3 0.0013 18.4 0.0 2.7 3 0 0 3 3 3 2 Type I restriction enzyme R protein N terminus (HSDR_N) Slx4 PF09494.5 EXF73822.1 - 0.0042 16.7 0.0 1.8 8.3 0.0 3.1 3 0 0 3 3 3 2 Slx4 endonuclease LysM PF01476.15 EXF73823.1 - 1.1e-16 60.3 1.2 1.1e-06 28.4 0.0 3.6 3 0 0 3 3 3 3 LysM domain Glyco_hydro_18 PF00704.23 EXF73824.1 - 1e-63 215.9 3.3 1.4e-63 215.4 2.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EXF73824.1 - 1.7e-11 43.8 31.3 6.8e-09 35.5 4.6 4.8 5 0 0 5 5 5 2 Chitin recognition protein Glyco_hydro_85 PF03644.8 EXF73824.1 - 0.00015 21.0 0.0 0.00026 20.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Ank_2 PF12796.2 EXF73825.1 - 2e-41 140.2 0.0 7.7e-10 38.9 0.1 7.1 2 2 6 8 8 8 8 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EXF73825.1 - 2.1e-32 110.8 1.4 1.3e-07 31.9 0.0 7.2 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF73825.1 - 2.4e-26 91.1 13.3 1.4e-07 31.5 0.0 9.7 8 3 3 11 11 11 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF73825.1 - 1.3e-22 77.6 6.4 0.0052 16.9 0.0 10.8 12 0 0 12 12 12 6 Ankyrin repeat Ank PF00023.25 EXF73825.1 - 1.3e-22 78.3 17.6 0.028 14.2 0.0 12.9 12 2 0 12 12 12 7 Ankyrin repeat HLH PF00010.21 EXF73826.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.4 2 0 0 2 2 2 0 Helix-loop-helix DNA-binding domain Glyco_hydro_88 PF07470.8 EXF73828.1 - 1.2e-61 208.6 5.3 1.4e-61 208.3 3.7 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Aminotran_1_2 PF00155.16 EXF73829.1 - 2.7e-42 145.0 0.0 3.3e-42 144.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EXF73829.1 - 0.00011 21.4 0.0 0.00017 20.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Hap4_Hap_bind PF10297.4 EXF73832.1 - 2.5e-08 33.4 6.0 2.5e-08 33.4 4.2 2.4 2 0 0 2 2 2 1 Minimal binding motif of Hap4 for binding to Hap2/3/5 bZIP_1 PF00170.16 EXF73832.1 - 3.1e-06 27.0 7.7 1.1e-05 25.2 5.4 2.0 1 1 0 1 1 1 1 bZIP transcription factor Macoilin PF09726.4 EXF73832.1 - 0.00013 20.4 5.7 0.00021 19.7 3.9 1.2 1 0 0 1 1 1 1 Transmembrane protein HAUS6_N PF14661.1 EXF73832.1 - 0.03 13.6 2.4 0.057 12.7 1.6 1.4 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus RBM39linker PF15519.1 EXF73832.1 - 0.13 12.5 0.7 0.73 10.1 0.0 2.7 2 0 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein SPX PF03105.14 EXF73832.1 - 0.39 10.4 7.7 0.44 10.2 4.0 1.8 1 1 0 1 1 1 0 SPX domain Hce2 PF14856.1 EXF73833.1 - 1.2e-15 57.1 0.3 1.7e-15 56.6 0.2 1.3 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor DUF2611 PF11022.3 EXF73833.1 - 0.1 12.6 0.7 0.68 10.0 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2611) Hce2 PF14856.1 EXF73834.1 - 1.1e-13 50.8 0.9 2.2e-13 49.9 0.7 1.5 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor Defensin_3 PF08131.6 EXF73834.1 - 4.1 7.4 6.6 0.48 10.4 1.2 2.1 2 0 0 2 2 2 0 Defensin-like peptide family COesterase PF00135.23 EXF73835.1 - 2.1e-76 257.7 0.0 8e-76 255.8 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF73835.1 - 9e-08 31.9 0.1 2.4e-07 30.5 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EXF73835.1 - 0.0064 15.7 0.4 0.015 14.4 0.3 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EXF73835.1 - 0.023 14.4 0.2 0.045 13.4 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pet191_N PF10203.4 EXF73836.1 - 0.99 9.4 4.5 3.4 7.7 2.1 2.4 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 CH PF00307.26 EXF73837.1 - 1.3e-10 41.2 0.0 2.2e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.6 EXF73837.1 - 0.0019 18.1 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 CDC24 Calponin NDUFA12 PF05071.11 EXF73838.1 - 5.1e-10 39.7 0.1 5.1e-10 39.7 0.1 2.0 2 0 0 2 2 2 1 NADH ubiquinone oxidoreductase subunit NDUFA12 cwf21 PF08312.7 EXF73839.1 - 7.7e-18 64.0 12.9 7.7e-18 64.0 8.9 2.1 2 0 0 2 2 2 1 cwf21 domain D123 PF07065.9 EXF73840.1 - 1.1e-85 287.3 0.0 7.1e-85 284.6 0.0 1.9 1 1 0 1 1 1 1 D123 DUF3716 PF12511.3 EXF73841.1 - 9.4e-16 57.1 9.7 1.5e-15 56.5 6.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Myc_N PF01056.13 EXF73841.1 - 0.033 13.3 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 Myc amino-terminal region G-alpha PF00503.15 EXF73842.1 - 6.5e-134 446.4 2.7 8.1e-134 446.1 1.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EXF73842.1 - 2.5e-15 56.1 1.7 2.3e-10 39.9 0.1 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family zf-CHC2 PF01807.15 EXF73842.1 - 9.6e-05 21.8 0.0 0.00041 19.8 0.0 2.0 2 0 0 2 2 2 1 CHC2 zinc finger Miro PF08477.8 EXF73842.1 - 0.0016 18.9 0.6 2.7 8.5 0.1 2.8 2 2 0 2 2 2 2 Miro-like protein Gtr1_RagA PF04670.7 EXF73842.1 - 0.0057 15.8 2.9 0.27 10.3 0.0 2.6 2 1 1 3 3 3 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EXF73842.1 - 0.0099 15.3 0.0 0.022 14.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.22 EXF73842.1 - 0.03 13.7 0.0 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MCM PF00493.18 EXF73842.1 - 0.085 11.6 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family MMR_HSR1 PF01926.18 EXF73842.1 - 0.11 12.4 0.0 16 5.4 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EXF73842.1 - 0.11 11.9 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Omega-toxin PF06357.6 EXF73843.1 - 0.031 13.8 4.0 0.077 12.5 2.8 1.7 1 0 0 1 1 1 0 Omega-atracotoxin Thioredoxin_6 PF13848.1 EXF73844.1 - 4.9e-24 85.1 0.8 1.5e-16 60.7 0.1 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin PF00085.15 EXF73844.1 - 1.3e-22 79.4 0.7 5.3e-11 42.1 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_2 PF13098.1 EXF73844.1 - 0.0024 18.0 0.3 0.037 14.2 0.0 2.8 2 1 0 2 2 2 1 Thioredoxin-like domain ERp29_N PF07912.8 EXF73844.1 - 0.0094 15.8 0.0 8.6 6.3 0.0 3.0 3 0 0 3 3 3 2 ERp29, N-terminal domain Thioredoxin_8 PF13905.1 EXF73844.1 - 0.051 13.7 0.1 2.2 8.4 0.0 3.0 3 0 0 3 3 3 0 Thioredoxin-like ERK-JNK_inhib PF15002.1 EXF73844.1 - 0.12 11.6 0.2 0.2 11.0 0.1 1.2 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor Ank PF00023.25 EXF73845.1 - 0.0011 18.6 0.0 0.52 10.2 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EXF73845.1 - 0.054 13.8 0.0 0.083 13.2 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ail_Lom PF06316.6 EXF73846.1 - 0.039 13.4 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 Enterobacterial Ail/Lom protein Pyr_redox_3 PF13738.1 EXF73847.1 - 4.7e-27 95.3 0.0 1.7e-26 93.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF73847.1 - 5e-07 29.6 0.0 3.8e-06 26.8 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EXF73847.1 - 8.9e-06 25.8 0.0 0.027 14.5 0.0 2.6 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.9 EXF73847.1 - 7.5e-05 22.6 0.0 1.4 8.7 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF73847.1 - 0.0023 17.7 0.3 0.054 13.2 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EXF73847.1 - 0.014 14.3 0.0 0.071 12.0 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase ThiF PF00899.16 EXF73847.1 - 0.049 13.4 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 0 ThiF family 2-Hacid_dh_C PF02826.14 EXF73847.1 - 0.049 12.7 0.0 0.15 11.1 0.0 1.7 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EXF73847.1 - 0.13 12.6 0.1 1.5 9.2 0.1 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DUF3328 PF11807.3 EXF73848.1 - 0.00024 20.8 4.0 0.00088 19.0 2.8 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3357 PF11837.3 EXF73848.1 - 0.015 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) ADH_zinc_N PF00107.21 EXF73850.1 - 9.1e-11 41.4 0.1 1.4e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF73850.1 - 1.5e-06 27.8 0.0 3.2e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EXF73850.1 - 0.0017 18.3 0.6 0.0029 17.6 0.4 1.4 1 0 0 1 1 1 1 NADH(P)-binding Polyketide_cyc2 PF10604.4 EXF73851.1 - 8.4e-16 58.3 0.0 1e-15 58.1 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Bet_v_1 PF00407.14 EXF73851.1 - 0.019 14.5 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 Pathogenesis-related protein Bet v I family Carb_anhydrase PF00194.16 EXF73852.1 - 3.9e-22 78.4 0.0 5.8e-22 77.9 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase OTT_1508_deam PF14441.1 EXF73853.1 - 5.1e-09 36.0 0.3 1e-08 35.1 0.2 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase Peptidase_M49 PF03571.10 EXF73853.1 - 0.06 11.4 0.1 0.084 10.9 0.0 1.1 1 0 0 1 1 1 0 Peptidase family M49 DUF911 PF06023.7 EXF73853.1 - 0.12 11.5 0.1 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 Archaeal protein of unknown function (DUF911) MFS_1 PF07690.11 EXF73854.1 - 1.2e-23 83.3 28.4 1.2e-23 83.3 19.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TauD PF02668.11 EXF73855.1 - 2.1e-41 142.2 0.2 3e-41 141.8 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Glyco_hydro_10 PF00331.15 EXF73857.1 - 1.4e-99 333.1 0.3 1.7e-99 332.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Frankia_peptide PF14407.1 EXF73857.1 - 0.041 13.6 0.0 0.086 12.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Glyco_hydro_42 PF02449.10 EXF73857.1 - 0.094 11.8 0.1 0.23 10.5 0.0 1.4 1 1 0 1 1 1 0 Beta-galactosidase Sugar_tr PF00083.19 EXF73858.1 - 1.1e-121 406.6 31.0 1.2e-121 406.4 21.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF73858.1 - 4e-17 61.9 63.0 5.6e-15 54.9 28.0 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily BT1 PF03092.11 EXF73858.1 - 3.8e-06 25.9 0.4 0.0033 16.1 0.0 2.4 2 1 0 2 2 2 2 BT1 family Myb_DNA-bind_6 PF13921.1 EXF73859.1 - 2e-19 69.4 9.5 6.4e-10 38.9 0.1 3.9 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EXF73859.1 - 3.1e-19 68.7 5.1 1.6e-08 34.4 0.1 3.7 3 0 0 3 3 3 3 Myb-like DNA-binding domain Amidohydro_1 PF01979.15 EXF73860.1 - 5.6e-20 72.2 2.1 1.1e-09 38.3 0.0 3.2 3 0 0 3 3 3 3 Amidohydrolase family Amidohydro_4 PF13147.1 EXF73860.1 - 3.7e-15 56.7 1.6 5.5e-10 39.7 0.2 2.6 1 1 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EXF73860.1 - 3.7e-10 39.4 0.3 1.9e-09 37.1 0.0 2.3 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_3 PF07969.6 EXF73860.1 - 1.8e-08 34.0 0.9 4.6e-05 22.8 0.2 2.9 2 1 0 2 2 2 2 Amidohydrolase family polyprenyl_synt PF00348.12 EXF73861.1 - 1.1e-54 185.0 0.0 2.5e-51 174.0 0.0 2.1 2 0 0 2 2 2 2 Polyprenyl synthetase HEPPP_synt_1 PF07307.6 EXF73861.1 - 0.02 14.3 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 Vma12 PF11712.3 EXF73862.1 - 2.6e-37 127.6 0.0 4.5e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase zf-C2H2_3 PF13878.1 EXF73862.1 - 5.4e-05 22.6 0.1 0.00013 21.5 0.0 1.7 2 0 0 2 2 2 1 zinc-finger of acetyl-transferase ESCO YqfD PF06898.6 EXF73862.1 - 0.14 10.7 0.9 0.22 10.2 0.7 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Cutinase PF01083.17 EXF73863.1 - 2.4e-58 196.8 0.1 2.9e-58 196.5 0.1 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.6 EXF73863.1 - 0.0025 17.6 0.0 0.0036 17.1 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_2 PF02230.11 EXF73863.1 - 0.014 14.8 0.1 0.023 14.1 0.0 1.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase PE-PPE PF08237.6 EXF73863.1 - 0.093 12.1 0.1 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain adh_short PF00106.20 EXF73864.1 - 1.4e-29 103.1 1.9 1.8e-29 102.8 1.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF73864.1 - 3.1e-26 92.6 0.2 3.6e-26 92.4 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF73864.1 - 1.5e-13 50.8 0.8 2.2e-13 50.2 0.6 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EXF73864.1 - 1.2e-05 25.0 0.1 2.1e-05 24.2 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EXF73864.1 - 0.007 15.7 0.2 0.014 14.8 0.0 1.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Methyltransf_31 PF13847.1 EXF73864.1 - 0.041 13.4 0.0 0.06 12.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Fungal_trans_2 PF11951.3 EXF73865.1 - 8.7e-44 149.6 0.5 1.2e-43 149.1 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF73865.1 - 7.3e-07 28.9 5.5 1.4e-06 28.0 3.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.16 EXF73866.1 - 1.2e-105 353.5 47.1 1.4e-105 353.3 32.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF73866.1 - 2.2e-24 85.7 51.7 2.9e-24 85.3 35.9 1.0 1 0 0 1 1 1 1 Amino acid permease Pyr_redox_3 PF13738.1 EXF73867.1 - 1.5e-23 83.9 0.0 2.2e-23 83.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EXF73867.1 - 1.1e-20 73.3 0.2 1.9e-19 69.3 0.0 2.2 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EXF73867.1 - 1.4e-11 44.2 0.0 6.3e-09 35.7 0.0 2.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EXF73867.1 - 1.8e-08 33.6 0.0 8.4e-06 24.9 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EXF73867.1 - 1e-05 25.3 0.0 0.0077 16.0 0.0 3.5 3 0 0 3 3 3 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EXF73867.1 - 0.00028 21.0 0.0 0.0026 17.8 0.0 2.4 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 EXF73867.1 - 0.002 17.1 0.0 0.043 12.7 0.0 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF73867.1 - 0.0034 16.3 0.0 0.0069 15.3 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EXF73867.1 - 0.0043 16.1 0.0 0.33 10.0 0.0 2.8 3 0 0 3 3 3 1 Thi4 family 2-Hacid_dh_C PF02826.14 EXF73867.1 - 0.0049 16.0 0.0 0.0093 15.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EXF73867.1 - 0.0059 16.9 0.0 0.048 13.9 0.0 2.4 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 EXF73867.1 - 0.018 14.9 0.0 3.5 7.4 0.0 3.1 2 1 1 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF73867.1 - 0.023 13.5 0.0 0.037 12.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain adh_short PF00106.20 EXF73868.1 - 2.6e-28 99.0 1.1 3.6e-28 98.5 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF73868.1 - 6.8e-24 84.9 0.3 8.3e-24 84.6 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF73868.1 - 7.7e-12 45.2 0.4 1.6e-11 44.2 0.3 1.5 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EXF73868.1 - 1.5e-06 27.3 0.3 3.7e-06 26.0 0.1 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EXF73868.1 - 1.2e-05 24.8 0.7 3.3e-05 23.4 0.5 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EXF73868.1 - 0.033 12.8 0.1 0.059 12.0 0.1 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.11 EXF73869.1 - 1e-39 136.2 47.3 1e-39 136.2 32.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF73869.1 - 0.00081 18.0 25.6 0.00081 18.0 17.8 2.4 1 1 1 2 2 2 1 Sugar (and other) transporter Glyco_hydro_31 PF01055.21 EXF73870.1 - 3.4e-130 434.8 4.6 4.2e-130 434.5 3.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EXF73870.1 - 8.2e-05 22.3 0.2 0.00053 19.7 0.0 2.6 2 1 0 2 2 2 1 Galactose mutarotase-like GMC_oxred_N PF00732.14 EXF73871.1 - 1.8e-64 217.7 0.2 2.8e-64 217.1 0.0 1.4 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF73871.1 - 9.7e-36 123.2 0.2 1.8e-35 122.3 0.2 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EXF73871.1 - 4.7e-07 28.9 0.0 0.0014 17.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EXF73871.1 - 0.00022 20.2 4.2 0.0012 17.8 3.0 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF73871.1 - 0.001 19.0 0.1 0.0033 17.4 0.1 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EXF73871.1 - 0.0027 16.7 0.0 0.0052 15.7 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 EXF73871.1 - 0.011 16.1 2.1 0.87 10.0 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EXF73871.1 - 0.12 12.3 0.5 0.45 10.5 0.1 2.0 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.9 EXF73871.1 - 0.15 10.4 0.0 0.29 9.5 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein PAP2 PF01569.16 EXF73873.1 - 4e-20 71.7 4.0 1e-19 70.4 2.8 1.7 1 0 0 1 1 1 1 PAP2 superfamily PAP2_C PF14360.1 EXF73873.1 - 2.3 8.5 4.5 0.7 10.1 0.2 2.4 3 1 0 3 3 3 0 PAP2 superfamily C-terminal Cutinase PF01083.17 EXF73874.1 - 8.8e-23 80.9 1.2 1.5e-22 80.1 0.9 1.4 1 0 0 1 1 1 1 Cutinase Pectate_lyase PF03211.8 EXF73876.1 - 5.6e-66 222.0 5.7 6.6e-66 221.7 4.0 1.0 1 0 0 1 1 1 1 Pectate lyase FAD_binding_3 PF01494.14 EXF73879.1 - 3e-09 36.4 1.5 3.4e-05 23.0 0.2 2.9 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EXF73879.1 - 2.5e-06 27.3 0.1 9.1e-06 25.6 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF73879.1 - 6.7e-06 25.2 0.1 8e-05 21.7 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF73879.1 - 1.3e-05 24.2 0.0 2.3e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EXF73879.1 - 0.0002 21.6 0.0 0.0086 16.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF73879.1 - 0.00083 19.2 0.1 0.0022 17.9 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF73879.1 - 0.0022 16.5 0.0 0.0036 15.8 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EXF73879.1 - 0.0094 14.8 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EXF73879.1 - 0.049 12.7 0.0 0.08 12.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Sugar_tr PF00083.19 EXF73880.1 - 3.8e-65 220.2 20.0 4.3e-65 220.0 13.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF73880.1 - 2.4e-16 59.3 17.8 2.4e-16 59.3 12.4 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily ATP_synt_H PF05493.8 EXF73880.1 - 0.032 14.2 2.9 0.032 14.2 2.0 3.0 4 1 1 5 5 5 0 ATP synthase subunit H MFS_2 PF13347.1 EXF73880.1 - 6.5 5.0 33.2 0.12 10.7 11.5 3.3 2 2 0 2 2 2 0 MFS/sugar transport protein rve_3 PF13683.1 EXF73881.1 - 0.1 12.1 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Methyltransf_24 PF13578.1 EXF73882.1 - 1.8e-16 60.8 0.0 2.9e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EXF73882.1 - 5.2e-11 41.9 0.0 8.5e-11 41.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EXF73882.1 - 4.1e-06 27.3 0.0 6.9e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF73882.1 - 0.001 19.0 0.0 0.0064 16.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain CmcI PF04989.7 EXF73882.1 - 0.071 12.4 0.0 0.11 11.8 0.0 1.4 1 1 0 1 1 1 0 Cephalosporin hydroxylase Abhydrolase_6 PF12697.2 EXF73884.1 - 1.4e-24 87.2 0.0 1.8e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF73884.1 - 1.7e-12 47.4 0.0 4.4e-12 46.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF73884.1 - 2.1e-10 40.5 0.0 4.8e-10 39.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EXF73884.1 - 0.0087 15.6 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.15 EXF73884.1 - 0.016 15.4 0.0 0.033 14.4 0.0 1.4 1 1 0 1 1 1 0 Thioesterase domain Esterase PF00756.15 EXF73884.1 - 0.025 14.0 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.11 EXF73884.1 - 0.046 13.1 0.1 2.3 7.6 0.0 3.0 3 1 1 4 4 4 0 Phospholipase/Carboxylesterase DUF2048 PF09752.4 EXF73884.1 - 0.11 11.3 0.0 0.13 11.0 0.0 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) MARVEL PF01284.18 EXF73885.1 - 2.4e-07 30.6 13.3 1.6e-06 27.9 9.2 1.9 1 1 0 1 1 1 1 Membrane-associating domain Spo7 PF03907.8 EXF73885.1 - 0.024 14.2 0.9 0.04 13.5 0.6 1.2 1 0 0 1 1 1 0 Spo7-like protein DUF1218 PF06749.7 EXF73885.1 - 1.8 9.0 6.3 1.6 9.1 2.4 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1218) Methyltransf_3 PF01596.12 EXF73886.1 - 8.7e-25 86.9 0.0 1.2e-24 86.5 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EXF73886.1 - 3.2e-12 47.2 0.0 5.1e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF73886.1 - 6.3e-08 33.1 0.0 1.2e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF73886.1 - 4.2e-07 29.6 0.0 6.1e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF73886.1 - 3.4e-06 27.0 0.0 6.3e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF73886.1 - 0.00013 21.7 0.0 0.00016 21.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF73886.1 - 0.00067 19.9 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF73886.1 - 0.00088 19.7 0.0 0.0017 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EXF73886.1 - 0.0025 17.3 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.10 EXF73886.1 - 0.0094 15.3 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 adh_short PF00106.20 EXF73888.1 - 3.9e-27 95.1 0.4 5.4e-27 94.7 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF73888.1 - 3.5e-16 59.7 0.0 5.3e-16 59.1 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF73888.1 - 2.8e-12 46.6 0.2 3.7e-12 46.2 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF73888.1 - 0.001 18.5 0.2 0.0023 17.4 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fibrillarin PF01269.12 EXF73888.1 - 0.019 13.8 0.1 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin PTR2 PF00854.16 EXF73889.1 - 7.7e-49 166.4 9.5 1.1e-48 165.9 6.6 1.2 1 0 0 1 1 1 1 POT family MFS_1 PF07690.11 EXF73889.1 - 3.3e-06 26.0 20.3 3.3e-06 26.0 14.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Pkinase PF00069.20 EXF73890.1 - 1.1e-60 204.9 0.0 8.9e-37 126.6 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EXF73890.1 - 8.2e-32 110.2 0.0 3.4e-21 75.4 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EXF73890.1 - 2.1e-12 46.6 0.0 5.7e-08 32.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EXF73890.1 - 0.0023 17.0 0.0 0.0053 15.8 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EXF73890.1 - 0.0056 16.4 0.0 0.018 14.7 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.20 EXF73891.1 - 0.00076 18.7 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF73891.1 - 0.0043 16.1 0.0 0.026 13.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Med12 PF09497.5 EXF73892.1 - 1e-27 95.8 0.2 7.5e-27 93.0 0.2 2.4 2 0 0 2 2 2 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 EXF73892.1 - 0.13 10.7 0.0 6.8 5.0 0.0 2.2 1 1 1 2 2 2 0 Eukaryotic Mediator 12 subunit domain UPF0139 PF03669.8 EXF73893.1 - 3.9e-05 23.1 0.0 5.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) ATP_transf PF09830.4 EXF73894.1 - 1.3e-12 47.3 0.0 2.1e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 ATP adenylyltransferase MOSC_N PF03476.11 EXF73895.1 - 1.9e-12 46.9 0.0 3.5e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EXF73895.1 - 3.8e-10 39.3 0.2 4e-09 36.0 0.2 2.2 1 1 0 1 1 1 1 MOSC domain MFS_1 PF07690.11 EXF73896.1 - 3.4e-32 111.5 41.3 3.4e-32 111.5 28.6 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF73896.1 - 1.2e-06 27.3 34.3 5.9e-06 25.1 4.9 2.7 2 1 0 3 3 3 2 Sugar (and other) transporter Tyrosinase PF00264.15 EXF73897.1 - 4.8e-33 115.1 5.2 7.9e-33 114.4 3.6 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Fanconi_C PF02106.10 EXF73897.1 - 0.016 13.6 0.0 0.023 13.1 0.0 1.1 1 0 0 1 1 1 0 Fanconi anaemia group C protein TPR_12 PF13424.1 EXF73898.1 - 5.9e-17 61.3 2.8 7.5e-05 22.5 0.0 5.1 3 1 1 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 EXF73898.1 - 1.1e-09 37.4 7.5 0.91 9.6 0.3 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 EXF73898.1 - 1.3e-09 37.6 1.1 0.069 13.1 0.0 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EXF73898.1 - 6.3e-07 28.7 3.2 0.54 10.1 0.0 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EXF73898.1 - 6.8e-07 29.5 5.6 0.027 14.7 0.7 4.4 2 1 2 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EXF73898.1 - 3.8e-06 26.9 0.4 0.0073 16.4 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EXF73898.1 - 5.8e-06 26.8 0.5 0.44 11.2 0.0 4.8 3 1 2 5 5 5 1 Tetratricopeptide repeat NB-ARC PF00931.17 EXF73898.1 - 7.4e-06 25.0 0.0 0.011 14.6 0.0 2.9 3 0 0 3 3 3 2 NB-ARC domain TPR_14 PF13428.1 EXF73898.1 - 1.2e-05 25.5 5.9 18 6.3 0.0 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 EXF73898.1 - 7.6e-05 22.2 6.7 0.25 11.0 0.2 4.4 2 1 5 7 7 7 4 TPR repeat AAA_22 PF13401.1 EXF73898.1 - 0.00016 21.8 0.0 0.00092 19.3 0.0 2.3 1 0 0 1 1 1 1 AAA domain TPR_1 PF00515.23 EXF73898.1 - 0.00042 19.7 5.0 6.8 6.4 0.1 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 EXF73898.1 - 0.0086 16.2 0.0 41 4.7 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat AAA_16 PF13191.1 EXF73898.1 - 0.009 16.0 0.3 0.084 12.8 0.0 2.8 2 1 0 2 2 2 1 AAA ATPase domain TPR_8 PF13181.1 EXF73898.1 - 0.011 15.4 1.1 33 4.5 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EXF73898.1 - 0.034 14.5 0.1 38 5.1 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat HEAT_EZ PF13513.1 EXF73900.1 - 2e-13 50.3 9.5 1e-06 29.0 0.0 8.4 8 2 3 11 11 11 2 HEAT-like repeat IBN_N PF03810.14 EXF73900.1 - 8.6e-13 48.0 3.5 1.3e-10 41.0 0.6 4.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT PF02985.17 EXF73900.1 - 1.8e-11 43.0 17.4 0.016 15.2 0.0 10.7 13 0 0 13 13 13 3 HEAT repeat HEAT_2 PF13646.1 EXF73900.1 - 2.5e-11 43.6 15.6 2.2e-05 24.6 0.0 7.7 3 2 5 8 8 8 4 HEAT repeats CLASP_N PF12348.3 EXF73900.1 - 1.1e-06 28.2 1.2 1.4 8.2 0.1 5.0 3 2 2 5 5 5 3 CLASP N terminal RIX1 PF08167.7 EXF73900.1 - 7.6e-05 22.4 0.0 0.79 9.3 0.0 4.9 1 1 3 5 5 5 1 rRNA processing/ribosome biogenesis HEAT_PBS PF03130.11 EXF73900.1 - 0.063 13.7 0.0 44 4.9 0.0 4.9 3 0 0 3 3 3 0 PBS lyase HEAT-like repeat Cse1 PF08506.5 EXF73900.1 - 0.1 11.1 0.0 5.5 5.4 0.0 3.3 2 1 1 3 3 3 0 Cse1 HMGL-like PF00682.14 EXF73901.1 - 6.4e-65 219.1 0.0 9.1e-65 218.6 0.0 1.2 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.5 EXF73901.1 - 2.7e-23 82.2 0.0 5.6e-23 81.1 0.0 1.6 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain Ferric_reduct PF01794.14 EXF73902.1 - 2.1e-20 73.0 10.1 2.1e-20 73.0 7.0 2.3 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EXF73902.1 - 2.4e-17 63.2 0.0 3.2e-15 56.3 0.0 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EXF73902.1 - 1.7e-12 47.1 0.0 3.9e-11 42.7 0.0 2.4 1 1 0 1 1 1 1 FAD-binding domain DUF3789 PF12664.2 EXF73902.1 - 0.66 9.3 2.7 1.8 7.9 1.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3789) DUF1690 PF07956.6 EXF73903.1 - 4.7e-34 117.3 2.3 5.5e-34 117.1 1.6 1.0 1 0 0 1 1 1 1 Protein of Unknown function (DUF1690) cwf21 PF08312.7 EXF73903.1 - 0.0083 15.9 1.1 0.026 14.3 0.4 2.1 1 1 1 2 2 2 1 cwf21 domain DUF3708 PF12501.3 EXF73903.1 - 0.022 14.5 0.4 0.032 14.0 0.3 1.2 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Lzipper-MIP1 PF14389.1 EXF73903.1 - 0.035 14.2 1.1 0.035 14.2 0.8 2.4 2 1 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Lebercilin PF15619.1 EXF73903.1 - 0.062 12.7 9.3 0.11 11.9 6.5 1.3 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF1409 PF07197.7 EXF73903.1 - 0.07 13.2 1.5 14 5.8 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) ALMT PF11744.3 EXF73903.1 - 0.083 11.5 0.3 0.088 11.4 0.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3779 PF12621.3 EXF73903.1 - 0.11 12.4 0.2 0.29 11.0 0.0 1.8 2 1 0 2 2 2 0 Phosphate metabolism protein Matrilin_ccoil PF10393.4 EXF73903.1 - 0.57 9.5 2.8 10 5.5 0.2 2.5 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Phage_GP20 PF06810.6 EXF73903.1 - 0.7 9.3 4.3 1.7 8.0 0.5 2.3 1 1 1 2 2 2 0 Phage minor structural protein GP20 Uds1 PF15456.1 EXF73903.1 - 2 8.4 9.2 1.7 8.6 4.2 2.2 2 0 0 2 2 2 0 Up-regulated During Septation THOC7 PF05615.8 EXF73903.1 - 6.6 7.0 11.1 63 3.8 6.1 2.4 2 1 0 2 2 2 0 Tho complex subunit 7 TYW3 PF02676.9 EXF73904.1 - 5.3e-61 205.3 0.0 7.2e-61 204.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase TYW3 PAPS_reduct PF01507.14 EXF73905.1 - 6.7e-44 149.7 0.2 1.9e-43 148.3 0.0 1.8 2 0 0 2 2 2 1 Phosphoadenosine phosphosulfate reductase family HAD PF12710.2 EXF73906.1 - 4.9e-18 65.9 0.1 7.5e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EXF73906.1 - 1e-10 42.4 2.2 8.5e-09 36.1 1.6 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EXF73906.1 - 6.6e-09 35.7 1.0 3.8e-08 33.2 0.0 2.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EXF73906.1 - 1.3e-05 25.4 0.0 4.4e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DUF705 PF05152.7 EXF73906.1 - 0.0017 17.3 0.1 0.0027 16.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF705) Put_Phosphatase PF06888.7 EXF73906.1 - 0.035 13.2 0.0 2.2 7.3 0.0 2.2 2 0 0 2 2 2 0 Putative Phosphatase zf-DHHC PF01529.15 EXF73908.1 - 7.3e-39 132.9 0.2 1.7e-38 131.7 0.2 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase Yip1 PF04893.12 EXF73908.1 - 0.0023 17.4 4.8 0.013 15.0 0.2 2.2 2 0 0 2 2 2 2 Yip1 domain Clr5 PF14420.1 EXF73909.1 - 5.2e-19 67.8 4.5 1.1e-18 66.7 3.1 1.6 1 0 0 1 1 1 1 Clr5 domain Fungal_trans PF04082.13 EXF73910.1 - 1.2e-15 57.1 0.0 3.7e-13 48.9 0.0 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain PhyH PF05721.8 EXF73911.1 - 3.5e-19 69.6 0.0 5.1e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Glyco_hydro_28 PF00295.12 EXF73913.1 - 1.3e-43 149.1 5.2 1.9e-43 148.6 3.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 FAD_binding_4 PF01565.18 EXF73914.1 - 2e-18 66.1 2.6 3.7e-18 65.3 1.8 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF73914.1 - 0.0072 16.2 0.1 0.018 14.9 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like RP-C PF03428.8 EXF73914.1 - 0.078 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Replication protein C N-terminal domain FMN_bind_2 PF04299.7 EXF73915.1 - 1.9e-49 167.4 0.0 2.2e-49 167.1 0.0 1.1 1 0 0 1 1 1 1 Putative FMN-binding domain EthD PF07110.6 EXF73916.1 - 5.7e-20 72.0 0.3 9.1e-20 71.3 0.2 1.3 1 0 0 1 1 1 1 EthD domain MFS_1 PF07690.11 EXF73917.1 - 5.9e-33 114.0 34.1 5.9e-33 114.0 23.6 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily SPC12 PF06645.8 EXF73917.1 - 4.3 7.2 6.1 14 5.5 0.0 3.7 3 1 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Ferric_reduct PF01794.14 EXF73918.1 - 1.8e-17 63.5 4.8 1.8e-17 63.5 3.3 2.4 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EXF73918.1 - 1.9e-14 53.4 0.1 1.3e-13 50.6 0.0 2.2 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_6 PF08030.7 EXF73918.1 - 5.8e-14 52.2 0.0 1.3e-12 47.8 0.0 2.4 2 1 0 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.16 EXF73918.1 - 0.00011 22.7 0.0 0.068 13.7 0.0 2.9 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain PAT1 PF09770.4 EXF73918.1 - 4.3 5.4 7.0 5.7 5.0 4.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Chromo PF00385.19 EXF73921.1 - 1.6e-05 24.4 0.0 2.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Glyco_hydro_61 PF03443.9 EXF73922.1 - 1.9e-47 161.9 0.0 3.3e-47 161.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 SNF2_N PF00176.18 EXF73925.1 - 3.7e-73 245.9 0.1 5e-73 245.4 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain CDO_I PF05995.7 EXF73925.1 - 8.3e-39 132.5 0.0 2e-38 131.3 0.0 1.6 1 0 0 1 1 1 1 Cysteine dioxygenase type I zf-RING_2 PF13639.1 EXF73925.1 - 1.3e-11 44.1 8.9 1.3e-11 44.1 6.2 1.8 2 0 0 2 2 1 1 Ring finger domain Helicase_C PF00271.26 EXF73925.1 - 2.3e-10 40.1 0.0 5.9e-10 38.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EXF73925.1 - 9.7e-10 38.3 13.7 1.6e-09 37.5 7.3 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EXF73925.1 - 8.2e-09 35.0 10.7 1e-08 34.6 5.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EXF73925.1 - 1.2e-08 34.4 9.4 1.2e-08 34.4 6.5 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) HIRAN PF08797.6 EXF73925.1 - 1.1e-07 31.7 0.0 2.8e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain zf-RING_5 PF14634.1 EXF73925.1 - 6.8e-07 28.9 9.2 1.6e-06 27.7 6.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EXF73925.1 - 2.5e-06 27.2 9.0 5.8e-06 26.0 6.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EXF73925.1 - 1.2e-05 25.3 2.9 3.6e-05 23.7 2.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EXF73925.1 - 0.00023 20.8 5.0 0.00062 19.4 3.4 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EXF73925.1 - 0.00058 19.5 10.3 0.00058 19.5 5.0 2.7 3 0 0 3 3 3 1 RING-type zinc-finger zf-Apc11 PF12861.2 EXF73925.1 - 0.00094 18.9 2.7 0.0031 17.3 1.9 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EXF73925.1 - 0.0052 16.3 5.6 0.012 15.2 3.9 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain TBCC PF07986.7 EXF73925.1 - 0.044 13.1 2.3 0.61 9.5 1.0 2.4 2 0 0 2 2 2 0 Tubulin binding cofactor C zf-Nse PF11789.3 EXF73925.1 - 0.084 12.3 6.3 0.21 11.1 4.0 1.9 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.1 EXF73925.1 - 1.3 8.6 5.0 1.2 8.7 2.3 1.9 2 0 0 2 2 1 0 Prokaryotic RING finger family 4 SLAC1 PF03595.12 EXF73926.1 - 1.7e-89 299.7 52.3 1.9e-89 299.6 36.2 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel DUF4577 PF15145.1 EXF73926.1 - 0.74 9.7 2.2 0.53 10.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) Radical_SAM PF04055.16 EXF73927.1 - 2.3e-24 86.4 0.1 8.1e-24 84.6 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Wyosine_form PF08608.7 EXF73927.1 - 1.1e-22 79.9 0.0 2.8e-22 78.5 0.0 1.8 1 0 0 1 1 1 1 Wyosine base formation Flavodoxin_1 PF00258.20 EXF73927.1 - 1e-11 44.9 0.4 1.4e-10 41.2 0.2 2.8 2 1 0 2 2 2 1 Flavodoxin MAS20 PF02064.10 EXF73928.1 - 1.8e-13 50.4 0.6 1.2e-12 47.7 0.4 1.9 1 1 0 1 1 1 1 MAS20 protein import receptor Rhabdo_ncap PF00945.13 EXF73928.1 - 0.0032 16.1 2.1 0.0038 15.8 1.4 1.0 1 0 0 1 1 1 1 Rhabdovirus nucleocapsid protein NAM-associated PF14303.1 EXF73928.1 - 0.077 13.3 5.0 0.1 12.8 3.5 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF4231 PF14015.1 EXF73928.1 - 0.093 12.7 3.9 0.14 12.1 2.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) DUF2215 PF10225.4 EXF73928.1 - 0.093 12.1 0.3 0.11 11.8 0.2 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) DUF533 PF04391.7 EXF73928.1 - 0.094 12.0 1.4 0.14 11.4 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Ctr PF04145.10 EXF73928.1 - 0.099 12.6 0.2 0.13 12.3 0.1 1.2 1 0 0 1 1 1 0 Ctr copper transporter family DUF3824 PF12868.2 EXF73928.1 - 0.25 12.2 4.0 0.42 11.5 2.7 1.5 1 1 0 1 1 1 0 Domain of unknwon function (DUF3824) Vps51 PF08700.6 EXF73929.1 - 1.2e-14 53.8 1.0 1.2e-14 53.8 0.7 2.1 3 0 0 3 3 3 1 Vps51/Vps67 Sec5 PF15469.1 EXF73929.1 - 0.0041 16.8 8.4 0.39 10.4 0.0 2.9 3 0 0 3 3 3 2 Exocyst complex component Sec5 Laminin_B PF00052.13 EXF73929.1 - 0.021 14.4 0.3 0.044 13.3 0.2 1.6 1 0 0 1 1 1 0 Laminin B (Domain IV) COG2 PF06148.6 EXF73929.1 - 0.61 9.9 6.4 0.13 12.0 0.5 2.4 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Metallophos PF00149.23 EXF73930.1 - 3e-44 150.8 1.0 3.9e-44 150.4 0.7 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3112 PF11309.3 EXF73931.1 - 5.9e-37 126.9 19.5 3.3e-36 124.5 6.7 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) SH3_9 PF14604.1 EXF73932.1 - 2.7e-06 26.8 0.1 5.1e-06 25.9 0.1 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EXF73932.1 - 7.1e-05 22.1 0.1 0.00015 21.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain DAP10 PF07213.6 EXF73932.1 - 0.017 14.8 0.2 0.056 13.1 0.2 1.9 1 0 0 1 1 1 0 DAP10 membrane protein DUF2668 PF10873.3 EXF73932.1 - 0.022 14.9 1.5 0.022 14.9 1.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2668) Gly-zipper_Omp PF13488.1 EXF73932.1 - 0.024 14.2 12.0 0.071 12.7 0.1 2.3 2 0 0 2 2 2 0 Glycine zipper DUF1183 PF06682.7 EXF73932.1 - 0.041 13.4 2.9 0.47 9.9 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) Gly-zipper_YMGG PF13441.1 EXF73932.1 - 6.2 6.4 16.9 2.5 7.6 0.6 2.3 2 0 0 2 2 2 0 YMGG-like Gly-zipper Pkinase PF00069.20 EXF73933.1 - 4.5e-23 81.7 0.0 7.7e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.17 EXF73933.1 - 1.5e-12 46.4 10.2 0.0069 16.3 0.1 6.9 6 0 0 6 6 6 4 HEAT repeat WD40 PF00400.27 EXF73933.1 - 4.1e-11 42.3 17.7 4.2e-08 32.7 0.1 5.4 5 0 0 5 5 5 3 WD domain, G-beta repeat HEAT_2 PF13646.1 EXF73933.1 - 3.1e-08 33.7 4.1 0.041 14.1 0.0 4.5 1 1 4 5 5 5 5 HEAT repeats Pkinase_Tyr PF07714.12 EXF73933.1 - 0.00011 21.3 0.0 0.00017 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_EZ PF13513.1 EXF73933.1 - 0.0033 17.8 5.9 0.021 15.2 0.3 4.3 5 0 0 5 5 5 1 HEAT-like repeat LRR_9 PF14580.1 EXF73934.1 - 1.8e-50 170.9 0.2 4.7e-50 169.5 0.0 1.6 2 0 0 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.2 EXF73934.1 - 6e-10 38.5 1.3 2e-05 24.1 0.0 3.3 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EXF73934.1 - 1.2e-09 37.7 1.0 3.8e-08 32.9 0.3 2.8 3 0 0 3 3 3 1 Leucine rich repeat LRR_7 PF13504.1 EXF73934.1 - 0.00079 19.2 2.0 2.1 8.8 0.0 4.7 4 0 0 4 4 4 1 Leucine rich repeat LRR_1 PF00560.28 EXF73934.1 - 0.019 14.9 2.7 99 3.6 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat UPF0128 PF03673.8 EXF73934.1 - 0.07 12.3 0.1 0.13 11.5 0.0 1.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0128) LRR_6 PF13516.1 EXF73934.1 - 0.22 11.6 1.2 38 4.7 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeat PspB PF06667.7 EXF73934.1 - 0.43 10.5 3.1 0.42 10.5 1.0 1.8 2 0 0 2 2 2 0 Phage shock protein B DUF4349 PF14257.1 EXF73934.1 - 0.89 8.7 7.1 0.11 11.7 2.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) CBFD_NFYB_HMF PF00808.18 EXF73935.1 - 6.1e-12 45.4 0.1 1.7e-11 43.9 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Voltage_CLC PF00654.15 EXF73936.1 - 2.8e-89 299.6 26.5 2.8e-89 299.6 18.4 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EXF73936.1 - 2.1e-11 43.3 0.1 6.4e-05 22.6 0.0 2.5 2 0 0 2 2 2 2 CBS domain EamA PF00892.15 EXF73937.1 - 0.00045 20.2 9.3 0.00071 19.6 6.1 1.6 1 1 1 2 2 2 1 EamA-like transporter family EmrE PF13536.1 EXF73937.1 - 0.016 15.3 5.1 0.016 15.3 3.6 1.9 1 1 0 2 2 2 0 Multidrug resistance efflux transporter UPF0546 PF10639.4 EXF73937.1 - 0.023 14.5 3.7 0.036 13.8 2.4 1.3 1 1 0 1 1 1 0 Uncharacterised protein family UPF0546 Ca_hom_mod PF14798.1 EXF73937.1 - 0.047 12.6 0.6 0.078 11.9 0.4 1.3 1 0 0 1 1 1 0 Calcium homeostasis modulator DUF4235 PF14019.1 EXF73937.1 - 2.3 8.1 5.4 23 4.9 3.7 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4235) TFIIA_gamma_C PF02751.9 EXF73938.1 - 3.7e-26 90.6 0.7 5e-26 90.2 0.5 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 EXF73938.1 - 7.2e-24 83.1 0.2 1e-23 82.6 0.2 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain ATP-synt_C PF00137.16 EXF73939.1 - 1.5e-25 88.8 32.0 4.1e-16 58.6 4.9 3.0 3 1 0 3 3 3 2 ATP synthase subunit C Oxidored_q2 PF00420.19 EXF73939.1 - 2 8.0 7.8 2 8.0 3.1 2.6 1 1 1 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L MoCF_biosynth PF00994.19 EXF73940.1 - 1.6e-54 183.2 0.9 3.5e-31 107.5 0.0 2.4 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 EXF73940.1 - 4.3e-34 117.2 3.3 7.3e-34 116.4 2.3 1.4 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 EXF73940.1 - 9.1e-16 57.5 0.1 2.6e-15 56.1 0.0 1.9 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) SelP_N PF04592.9 EXF73940.1 - 0.13 11.6 9.2 0.19 11.0 6.4 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RNase_P_Rpp14 PF01900.14 EXF73941.1 - 1.7e-35 121.1 0.0 2.2e-35 120.7 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family ATP_bind_1 PF03029.12 EXF73942.1 - 3.2e-77 259.3 0.0 4.3e-77 258.8 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein ArgK PF03308.11 EXF73942.1 - 0.0045 15.8 0.0 0.0078 15.0 0.0 1.3 1 0 0 1 1 1 1 ArgK protein AAA_10 PF12846.2 EXF73942.1 - 0.0055 16.1 0.0 0.03 13.7 0.0 2.0 1 1 0 1 1 1 1 AAA-like domain AAA_29 PF13555.1 EXF73942.1 - 0.0055 16.2 0.0 0.01 15.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EXF73942.1 - 0.0089 16.8 0.6 0.031 15.1 0.4 2.2 1 1 0 1 1 1 1 AAA domain CbiA PF01656.18 EXF73942.1 - 0.051 12.9 0.0 0.17 11.2 0.0 1.8 1 1 1 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.1 EXF73942.1 - 0.07 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EXF73942.1 - 0.077 12.4 0.0 0.21 11.0 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family GTP_EFTU PF00009.22 EXF73942.1 - 0.087 12.2 0.0 0.49 9.7 0.0 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EXF73942.1 - 0.14 12.0 0.0 0.77 9.7 0.0 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase cNMP_binding PF00027.24 EXF73943.1 - 1.6e-38 130.3 0.1 2.6e-18 65.6 0.0 4.6 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Patatin PF01734.17 EXF73943.1 - 5.3e-16 59.1 3.6 9.2e-15 55.1 2.5 2.7 1 1 0 1 1 1 1 Patatin-like phospholipase MIP-T3 PF10243.4 EXF73944.1 - 0.42 9.0 10.4 0.47 8.8 7.2 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Pyridoxal_deC PF00282.14 EXF73945.1 - 5.3e-118 393.6 0.0 6.3e-118 393.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain ATP-grasp_4 PF13535.1 EXF73946.1 - 1.3e-09 38.0 0.0 4.5e-07 29.7 0.0 2.7 2 1 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EXF73946.1 - 3.2e-09 35.9 0.0 1.1e-08 34.2 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon CP2 PF04516.10 EXF73947.1 - 2.2e-84 282.1 0.0 3.4e-84 281.5 0.0 1.2 1 0 0 1 1 1 1 CP2 transcription factor Tektin PF03148.9 EXF73947.1 - 0.039 12.5 0.0 0.064 11.7 0.0 1.2 1 0 0 1 1 1 0 Tektin family Phage_G PF02306.10 EXF73947.1 - 0.041 13.5 0.1 0.079 12.5 0.1 1.4 1 0 0 1 1 1 0 Major spike protein (G protein) Not3 PF04065.10 EXF73947.1 - 0.11 11.7 0.7 0.18 11.0 0.5 1.2 1 0 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component FAD_binding_4 PF01565.18 EXF73953.1 - 6.4e-09 35.4 0.0 0.00022 20.7 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain ALO PF04030.9 EXF73953.1 - 2.6e-07 30.5 1.5 0.0043 16.6 0.1 2.2 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase HET PF06985.6 EXF73954.1 - 0.045 13.9 0.2 0.12 12.5 0.2 1.7 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 EXF73955.1 - 1.1e-35 122.9 36.3 2.9e-35 121.6 24.0 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF605 PF04652.11 EXF73956.1 - 2.2 7.5 9.0 2.9 7.2 6.3 1.1 1 0 0 1 1 1 0 Vta1 like Ank PF00023.25 EXF73957.1 - 3.9e-11 42.1 0.0 9.9e-05 21.9 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.2 EXF73957.1 - 8.2e-09 35.6 0.0 0.0012 19.1 0.0 3.2 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EXF73957.1 - 4.3e-08 32.6 0.0 0.003 17.6 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EXF73957.1 - 1.4e-05 25.2 0.0 0.0011 19.2 0.0 2.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EXF73957.1 - 2.1e-05 24.8 0.0 0.0061 17.0 0.0 4.2 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Sep15_SelM PF08806.6 EXF73957.1 - 0.092 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Sep15/SelM redox domain Glyco_hydro_18 PF00704.23 EXF73960.1 - 2e-38 132.7 2.4 1.9e-37 129.5 1.7 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EXF73960.1 - 4.8e-07 29.6 21.2 4.8e-07 29.6 14.7 2.1 2 0 0 2 2 2 1 Chitin recognition protein DUF4015 PF13200.1 EXF73960.1 - 0.00069 18.6 0.0 0.00097 18.1 0.0 1.1 1 0 0 1 1 1 1 Putative glycosyl hydrolase domain 2OG-FeII_Oxy PF03171.15 EXF73961.1 - 1.7e-22 79.5 0.0 4.7e-22 78.1 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EXF73961.1 - 9e-16 58.4 0.0 1.6e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal DUF167 PF02594.11 EXF73962.1 - 2.1e-17 62.8 0.2 4e-17 61.9 0.1 1.5 2 0 0 2 2 2 1 Uncharacterised ACR, YggU family COG1872 PetM PF08041.6 EXF73963.1 - 0.72 9.3 5.2 8.7 5.9 0.2 2.8 2 0 0 2 2 2 0 PetM family of cytochrome b6f complex subunit 7 p450 PF00067.17 EXF73964.1 - 4.9e-60 203.3 0.0 7e-60 202.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_28 PF00295.12 EXF73965.1 - 9.2e-41 139.8 10.2 2.7e-39 135.0 4.6 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EXF73965.1 - 5.9 6.6 17.3 1.8e+02 1.7 12.0 2.9 1 1 1 2 2 2 0 Right handed beta helix region PUF PF00806.14 EXF73966.1 - 3.8e-12 44.9 0.0 0.12 11.9 0.0 6.2 6 0 0 6 6 6 4 Pumilio-family RNA binding repeat Pyridoxal_deC PF00282.14 EXF73967.1 - 4.6e-78 262.2 0.0 6e-78 261.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EXF73967.1 - 1.2e-05 24.5 0.0 1.8e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EXF73967.1 - 0.0039 15.9 0.0 0.0065 15.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Exonuc_VII_S PF02609.11 EXF73968.1 - 0.0034 17.1 0.4 0.027 14.2 0.1 2.6 2 0 0 2 2 2 1 Exonuclease VII small subunit E2R135 PF11570.3 EXF73969.1 - 0.00036 20.6 0.4 0.00089 19.3 0.2 1.6 1 0 0 1 1 1 1 Coiled-coil receptor-binding R-domain of colicin E2 Laminin_I PF06008.9 EXF73969.1 - 0.13 11.5 0.1 0.13 11.5 0.0 2.6 3 1 0 3 3 3 0 Laminin Domain I Syntaxin_2 PF14523.1 EXF73969.1 - 5.8 7.0 6.3 5.6 7.0 0.6 3.1 4 0 0 4 4 4 0 Syntaxin-like protein Peptidase_C58 PF03543.9 EXF73970.1 - 4.6e-05 23.0 0.0 0.033 13.6 0.0 2.2 2 0 0 2 2 2 2 Yersinia/Haemophilus virulence surface antigen Ras PF00071.17 EXF73971.1 - 4.9e-39 133.3 0.0 2.1e-25 88.9 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EXF73971.1 - 2.7e-12 47.2 0.0 7e-12 45.9 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EXF73971.1 - 0.00025 20.3 0.0 0.00086 18.5 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EXF73971.1 - 0.00032 20.6 0.0 0.00056 19.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EXF73971.1 - 0.0051 16.2 0.0 0.2 11.0 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EXF73971.1 - 0.034 14.1 0.0 0.062 13.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain PRK PF00485.13 EXF73971.1 - 0.051 13.1 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family XFP_N PF09364.5 EXF73972.1 - 5.4e-173 574.8 0.0 7e-173 574.5 0.0 1.1 1 0 0 1 1 1 1 XFP N-terminal domain XFP PF03894.10 EXF73972.1 - 5e-83 277.0 0.0 1.2e-82 275.8 0.0 1.6 2 0 0 2 2 2 1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase XFP_C PF09363.5 EXF73972.1 - 7.1e-83 277.0 0.0 1e-82 276.5 0.0 1.2 1 0 0 1 1 1 1 XFP C-terminal domain Oxidored_FMN PF00724.15 EXF73975.1 - 1.5e-46 158.9 0.0 1.8e-46 158.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Abhydrolase_5 PF12695.2 EXF73977.1 - 1e-10 41.5 0.1 2.2e-10 40.4 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF73977.1 - 9.5e-09 35.4 2.6 9.5e-09 35.4 1.8 1.4 2 0 0 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.6 EXF73977.1 - 2e-07 29.9 0.0 2.9e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.13 EXF73977.1 - 0.00015 21.3 0.3 0.00036 20.0 0.1 1.6 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 EXF73977.1 - 0.00015 21.0 0.0 0.00034 19.8 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.13 EXF73977.1 - 0.0072 15.6 0.0 0.045 13.0 0.0 2.1 2 1 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.7 EXF73977.1 - 0.021 13.3 0.0 1.8 7.0 0.0 2.2 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 EXF73977.1 - 0.028 14.1 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Zn_clus PF00172.13 EXF73979.1 - 7.3e-05 22.5 5.1 0.00014 21.6 3.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF73979.1 - 0.0043 15.7 0.0 0.0074 14.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Integrin_alpha PF00357.15 EXF73979.1 - 0.13 12.0 0.2 0.33 10.8 0.2 1.7 1 0 0 1 1 1 0 Integrin alpha cytoplasmic region DNA_pol_A_exo1 PF01612.15 EXF73980.1 - 7.7e-13 48.2 0.0 5.2e-12 45.6 0.0 2.0 1 1 0 1 1 1 1 3'-5' exonuclease T4_neck-protein PF11649.3 EXF73980.1 - 0.04 13.1 0.0 0.074 12.3 0.0 1.3 1 0 0 1 1 1 0 Virus neck protein MFS_1 PF07690.11 EXF73981.1 - 1.7e-13 49.9 10.0 1.7e-13 49.9 6.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1049 PF06305.6 EXF73981.1 - 1.7 8.1 11.7 0.74 9.3 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF1049) Glyco_hydro_61 PF03443.9 EXF73982.1 - 1.8e-64 217.5 0.4 2.2e-64 217.2 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 EXF73982.1 - 0.043 13.8 0.2 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Peptidase_M20 PF01546.23 EXF73983.1 - 7.8e-30 103.7 0.0 9.7e-30 103.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 EXF73983.1 - 0.00038 20.2 0.0 0.0008 19.1 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 M20_dimer PF07687.9 EXF73983.1 - 0.0054 16.4 0.0 0.021 14.5 0.0 1.9 2 1 0 2 2 2 1 Peptidase dimerisation domain EHN PF06441.7 EXF73984.1 - 3.4e-38 130.0 1.0 1.7e-37 127.7 0.0 2.1 2 0 0 2 2 2 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EXF73984.1 - 2.5e-12 47.1 0.2 6.2e-12 45.8 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF73984.1 - 1.9e-08 34.1 0.0 2.6e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold MIP PF00230.15 EXF73985.1 - 5.6e-45 153.5 15.0 7e-45 153.2 10.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein WD40 PF00400.27 EXF73986.1 - 0.011 15.5 1.1 0.85 9.6 0.0 3.5 4 0 0 4 4 4 0 WD domain, G-beta repeat DUF3420 PF11900.3 EXF73986.1 - 0.14 12.2 0.1 0.26 11.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3420) Fungal_trans PF04082.13 EXF73987.1 - 1.7e-15 56.6 3.1 1.7e-15 56.6 2.1 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EXF73987.1 - 1.6e-05 24.9 1.7 1.6e-05 24.9 1.2 2.9 2 0 0 2 2 2 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF73987.1 - 6.3e-05 23.0 1.5 6.3e-05 23.0 1.0 3.0 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EXF73987.1 - 0.0011 19.2 7.5 0.037 14.3 2.4 2.6 2 0 0 2 2 2 2 Zinc-finger double domain FAD_binding_3 PF01494.14 EXF73988.1 - 7.2e-19 68.0 0.0 1.2e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Lactamase_B PF00753.22 EXF73988.1 - 2e-07 30.8 1.0 5.1e-07 29.5 0.6 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 EXF73988.1 - 2.1e-06 27.5 0.1 0.00044 20.0 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 EXF73988.1 - 7.3e-05 22.4 0.0 0.00016 21.2 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain FAD_binding_3 PF01494.14 EXF73989.1 - 5.1e-12 45.5 0.7 4.5e-07 29.2 0.0 3.2 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 EXF73989.1 - 4.4e-05 23.4 0.1 0.0001 22.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EXF73989.1 - 7.4e-05 22.5 0.0 0.00012 21.8 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.19 EXF73989.1 - 0.00028 19.9 0.1 0.00042 19.3 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EXF73989.1 - 0.033 12.8 0.0 0.25 9.8 0.0 2.0 2 0 0 2 2 2 0 Tryptophan halogenase K_oxygenase PF13434.1 EXF73989.1 - 0.061 12.2 0.0 0.091 11.6 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Aldo_ket_red PF00248.16 EXF73990.1 - 3.9e-36 124.3 0.0 4.4e-36 124.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.17 EXF73991.1 - 7.4e-58 196.1 0.0 1.1e-57 195.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EXF73992.1 - 1.1e-27 96.9 0.0 2.5e-14 53.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EXF73992.1 - 0.00018 21.4 0.6 0.00042 20.2 0.4 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EXF73992.1 - 0.0012 17.5 0.4 0.024 13.2 0.2 2.0 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.19 EXF73992.1 - 0.014 14.2 0.3 0.05 12.4 0.3 1.7 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 EXF73992.1 - 0.03 13.2 2.3 0.063 12.1 0.9 1.9 1 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EXF73992.1 - 0.11 12.2 0.8 4.7 6.9 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Abhydrolase_4 PF08386.5 EXF73994.1 - 5.6e-14 51.8 0.0 1.5e-13 50.5 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EXF73994.1 - 1.9e-10 40.7 0.0 2.9e-09 36.8 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EXF73994.1 - 1.4e-09 38.1 2.5 7.2e-09 35.8 1.7 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF73994.1 - 0.0053 16.5 0.0 0.023 14.4 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Sugar_tr PF00083.19 EXF73995.1 - 1.4e-78 264.5 23.3 1.7e-78 264.2 16.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF73995.1 - 2.8e-13 49.3 43.4 5.7e-13 48.3 12.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_2 PF04909.9 EXF73996.1 - 1.6e-25 90.2 0.2 1.9e-25 89.9 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase UCH PF00443.24 EXF73997.1 - 9.1e-40 136.4 0.0 1.3e-39 135.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RPT PF13446.1 EXF73997.1 - 2.3e-14 52.5 3.9 1.2e-10 40.6 0.0 3.8 3 1 1 4 4 4 2 A repeated domain in UCH-protein UCH_1 PF13423.1 EXF73997.1 - 2.1e-09 37.2 0.3 0.0007 19.1 0.0 2.4 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Tim17 PF02466.14 EXF73998.1 - 1.6e-10 41.0 9.7 2.7e-10 40.3 6.7 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family MutS_V PF00488.16 EXF73999.1 - 7.2e-99 329.9 0.0 1.3e-98 329.1 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EXF73999.1 - 5.7e-40 137.2 0.9 1.1e-39 136.3 0.7 1.5 1 0 0 1 1 1 1 MutS domain III MutS_II PF05188.12 EXF73999.1 - 4.7e-23 81.7 2.0 5.3e-22 78.3 0.1 2.9 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.15 EXF73999.1 - 2.3e-20 72.7 0.0 1e-19 70.6 0.0 2.1 2 0 0 2 2 2 1 MutS domain I MutS_IV PF05190.13 EXF73999.1 - 4e-17 62.1 3.6 4.3e-17 62.0 0.9 2.3 2 0 0 2 2 2 1 MutS family domain IV Peptidase_M16 PF00675.15 EXF73999.1 - 0.035 13.8 0.2 0.12 12.1 0.1 1.9 2 0 0 2 2 2 0 Insulinase (Peptidase family M16) tRNA_m1G_MT PF01746.16 EXF74000.1 - 8.7e-35 120.0 0.0 3.7e-25 88.5 0.0 2.2 2 0 0 2 2 2 2 tRNA (Guanine-1)-methyltransferase DNA_primase_S PF01896.14 EXF74001.1 - 4.4e-54 182.2 0.1 7e-54 181.5 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit HSF_DNA-bind PF00447.12 EXF74002.1 - 4.4e-37 126.3 1.6 9.4e-37 125.3 1.1 1.5 1 0 0 1 1 1 1 HSF-type DNA-binding Response_reg PF00072.19 EXF74002.1 - 1.3e-19 70.2 0.0 2.5e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain DUF972 PF06156.8 EXF74002.1 - 0.046 14.0 2.4 0.11 12.9 1.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF16 PF01519.11 EXF74002.1 - 0.1 12.8 5.7 0.21 11.8 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF16 SlyX PF04102.7 EXF74002.1 - 3 8.2 10.7 2.2 8.6 5.4 2.2 1 1 1 2 2 2 0 SlyX IncA PF04156.9 EXF74002.1 - 3.2 7.3 6.8 5.2 6.6 4.7 1.2 1 0 0 1 1 1 0 IncA protein Fic PF02661.13 EXF74003.1 - 7.2e-17 61.8 0.0 5.5e-16 59.0 0.0 2.2 2 0 0 2 2 2 1 Fic/DOC family Metallophos PF00149.23 EXF74004.1 - 2.7e-08 33.4 0.6 6.9e-08 32.1 0.4 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EXF74004.1 - 1.2e-07 31.7 0.0 2e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain W2 PF02020.13 EXF74005.1 - 1.2e-17 63.6 1.5 2.8e-17 62.4 1.0 1.6 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 EXF74005.1 - 1.6e-08 33.6 8.7 1.7e-05 24.1 1.8 4.0 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EXF74005.1 - 0.0012 18.1 0.0 0.0021 17.3 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 EXF74005.1 - 0.0038 16.7 7.0 0.17 11.4 0.8 4.1 2 2 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 EXF74005.1 - 0.0073 16.3 0.0 0.02 14.9 0.0 1.8 1 0 0 1 1 1 1 MobA-like NTP transferase domain DUF2410 PF10307.4 EXF74006.1 - 1.4e-80 269.3 0.0 1.9e-80 268.9 0.0 1.2 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) CobU PF02283.11 EXF74007.1 - 0.36 10.2 2.6 0.74 9.2 1.8 1.5 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Abhydrolase_3 PF07859.8 EXF74008.1 - 4.6e-48 163.5 0.0 6.1e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF74008.1 - 2.3e-06 27.4 0.2 4.2e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EXF74008.1 - 3.4e-06 26.0 1.4 4.7e-05 22.3 1.0 2.0 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EXF74008.1 - 0.0033 16.6 0.1 0.037 13.2 0.4 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.7 EXF74008.1 - 0.067 11.6 0.0 0.12 10.8 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Lipase_GDSL PF00657.17 EXF74009.1 - 9.9e-14 51.7 0.2 1.2e-13 51.4 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EXF74009.1 - 2.2e-13 50.7 0.4 3.1e-13 50.2 0.3 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family MFS_1 PF07690.11 EXF74011.1 - 1.3e-30 106.2 64.1 4.8e-28 97.8 24.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Mem_trans PF03547.13 EXF74011.1 - 0.027 12.7 0.3 0.057 11.7 0.2 1.5 1 0 0 1 1 1 0 Membrane transport protein DUF2781 PF10914.3 EXF74011.1 - 0.19 11.4 3.3 0.51 10.1 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2781) NmrA PF05368.8 EXF74013.1 - 5.3e-36 124.0 0.0 6.8e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF74013.1 - 1.8e-12 47.6 0.0 2.5e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EXF74013.1 - 2.9e-05 22.9 0.0 4.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EXF74013.1 - 8.7e-05 22.5 1.1 0.0002 21.3 0.7 1.6 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 EXF74013.1 - 0.00012 21.8 0.4 0.00018 21.2 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF74013.1 - 0.00018 21.0 0.0 0.00034 20.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EXF74013.1 - 0.00072 18.5 0.0 0.013 14.4 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 EXF74013.1 - 0.035 13.0 0.0 0.052 12.4 0.0 1.4 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 EXF74015.1 - 7e-17 61.6 0.0 3.9e-16 59.1 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EXF74015.1 - 2.6e-13 49.3 0.0 6.9e-13 47.9 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EXF74015.1 - 7.7e-12 45.5 0.0 1.8e-11 44.3 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EXF74015.1 - 1.3e-08 34.1 0.0 0.00012 21.1 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.8 EXF74015.1 - 1e-07 31.4 0.0 1.6e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EXF74015.1 - 2.5e-05 23.3 0.0 4.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EXF74015.1 - 3.5e-05 23.7 0.1 0.0001 22.2 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase Fungal_trans PF04082.13 EXF74016.1 - 1e-15 57.3 0.1 2.2e-15 56.2 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pectate_lyase_3 PF12708.2 EXF74018.1 - 3.2e-05 24.1 0.2 0.002 18.3 0.1 2.5 1 1 0 1 1 1 1 Pectate lyase superfamily protein Rpn3_C PF08375.6 EXF74019.1 - 1e-24 86.6 1.4 2.9e-24 85.2 1.0 1.8 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EXF74019.1 - 3.6e-20 72.2 0.1 1.3e-19 70.4 0.0 2.0 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.12 EXF74019.1 - 0.0065 16.3 0.1 0.021 14.6 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TFIID_20kDa PF03847.8 EXF74020.1 - 4.6e-18 65.2 0.1 9.7e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.18 EXF74020.1 - 0.022 14.8 1.0 0.15 12.1 0.0 2.7 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Vfa1 PF08432.5 EXF74021.1 - 0.46 10.4 20.9 1.4 8.9 8.3 2.4 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 TFIIF_alpha PF05793.7 EXF74021.1 - 8.2 4.6 40.7 0.88 7.8 21.4 2.3 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) HMG_box PF00505.14 EXF74022.1 - 1.2e-08 35.0 0.3 2.9e-08 33.8 0.2 1.7 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EXF74022.1 - 7.4e-05 23.0 0.2 0.00025 21.3 0.1 2.0 1 0 0 1 1 1 1 HMG-box domain DUF399 PF04187.8 EXF74022.1 - 0.49 9.8 3.7 0.64 9.4 2.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF399 DUF3275 PF11679.3 EXF74022.1 - 3 7.4 5.7 2.7 7.5 2.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3275) Herpes_DNAp_acc PF04929.7 EXF74022.1 - 3.4 6.5 9.7 5 5.9 6.7 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Amidohydro_1 PF01979.15 EXF74023.1 - 1.2e-62 212.5 1.5 2e-62 211.7 1.0 1.4 1 0 0 1 1 1 1 Amidohydrolase family Urease_alpha PF00449.15 EXF74023.1 - 6e-54 181.3 1.5 6e-54 181.3 1.1 2.0 2 0 0 2 2 2 1 Urease alpha-subunit, N-terminal domain Urease_beta PF00699.15 EXF74023.1 - 4.9e-41 138.6 1.4 1.1e-40 137.5 0.1 2.2 3 0 0 3 3 3 1 Urease beta subunit Urease_gamma PF00547.13 EXF74023.1 - 2.7e-40 136.4 0.0 6.4e-40 135.1 0.0 1.7 1 0 0 1 1 1 1 Urease, gamma subunit Amidohydro_5 PF13594.1 EXF74023.1 - 9.2e-07 28.5 3.6 2.5e-06 27.1 2.5 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EXF74023.1 - 5.3e-05 22.6 1.7 0.00093 18.5 0.1 2.5 1 1 1 2 2 2 1 Amidohydrolase family Amidohydro_2 PF04909.9 EXF74023.1 - 0.0085 15.6 0.0 0.045 13.3 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 EXF74023.1 - 0.017 15.2 0.2 0.27 11.2 0.1 2.4 2 0 0 2 2 2 0 Amidohydrolase DUF1212 PF06738.7 EXF74024.1 - 0.011 15.1 1.4 0.02 14.3 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) Ada3 PF10198.4 EXF74025.1 - 1.9e-45 153.8 0.1 1.9e-45 153.8 0.0 3.1 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 Ribosomal_60s PF00428.14 EXF74025.1 - 0.044 14.1 18.1 0.062 13.6 8.1 3.2 2 1 0 2 2 2 0 60s Acidic ribosomal protein Med2 PF11214.3 EXF74025.1 - 0.83 9.7 6.1 14 5.7 0.0 3.0 3 0 0 3 3 3 0 Mediator complex subunit 2 DUF3419 PF11899.3 EXF74026.1 - 6.2e-158 525.4 0.1 8.9e-158 524.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_23 PF13489.1 EXF74026.1 - 4.5e-14 52.4 0.0 8.6e-13 48.3 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF74026.1 - 3.3e-09 37.3 0.0 1.6e-08 35.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF74026.1 - 5.5e-09 35.7 0.0 4.7e-08 32.7 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF74026.1 - 1.8e-08 34.7 0.0 8.6e-08 32.5 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF74026.1 - 9.3e-08 31.4 0.1 0.00025 20.2 0.0 2.7 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EXF74026.1 - 1.6e-07 31.3 0.1 3.3e-05 23.9 0.0 3.5 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF74026.1 - 9.5e-07 29.2 0.0 0.0029 18.0 0.0 3.9 4 0 0 4 4 4 1 Methyltransferase domain PCMT PF01135.14 EXF74026.1 - 7.5e-05 22.3 0.0 0.00015 21.3 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EXF74026.1 - 0.0082 15.8 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.12 EXF74026.1 - 0.054 12.8 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase CybS PF05328.7 EXF74027.1 - 2.4e-49 166.3 0.0 3.1e-49 165.9 0.0 1.1 1 0 0 1 1 1 1 CybS Sdh_cyt PF01127.17 EXF74027.1 - 0.0041 16.9 0.5 0.19 11.5 0.3 2.2 1 1 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit MFS_1 PF07690.11 EXF74027.1 - 0.053 12.2 0.3 0.073 11.7 0.2 1.1 1 0 0 1 1 1 0 Major Facilitator Superfamily tRNA-synt_1b PF00579.20 EXF74028.1 - 7.2e-76 255.0 0.0 1.1e-75 254.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) NPR2 PF06218.6 EXF74029.1 - 1.1e-112 376.8 0.0 6e-97 325.0 0.0 2.1 1 1 1 2 2 2 2 Nitrogen permease regulator 2 ubiquitin PF00240.18 EXF74030.1 - 4.4e-19 67.6 0.1 6.8e-19 67.0 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EXF74030.1 - 8.5e-10 38.1 1.3 3.7e-08 32.9 0.0 2.5 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.3 EXF74030.1 - 0.00024 20.7 0.1 0.00036 20.1 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EXF74030.1 - 0.00045 20.0 0.0 0.0009 19.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ADH_zinc_N PF00107.21 EXF74031.1 - 6.9e-35 119.4 1.9 1.1e-34 118.8 1.3 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF74031.1 - 2.2e-12 47.9 0.5 3.6e-12 47.2 0.1 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF74031.1 - 1.1e-07 31.5 0.0 4.2e-07 29.6 0.0 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EXF74031.1 - 0.0047 16.5 4.3 0.025 14.1 1.5 2.1 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EXF74031.1 - 0.02 14.9 0.1 0.037 14.0 0.1 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_10 PF13460.1 EXF74031.1 - 0.049 13.6 1.2 0.076 13.0 0.8 1.3 1 0 0 1 1 1 0 NADH(P)-binding DUF1254 PF06863.7 EXF74031.1 - 0.064 13.0 0.0 0.17 11.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1254) IBN_N PF03810.14 EXF74032.1 - 1.4e-12 47.3 0.1 4.5e-11 42.5 0.0 3.5 2 1 1 3 3 3 2 Importin-beta N-terminal domain Xpo1 PF08389.7 EXF74032.1 - 0.00095 19.1 0.0 0.0078 16.1 0.0 2.5 2 0 0 2 2 2 1 Exportin 1-like protein Fungal_trans PF04082.13 EXF74033.1 - 1.5e-11 43.7 0.1 2e-11 43.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF74033.1 - 4.2e-08 32.9 7.8 8.8e-08 31.9 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pex2_Pex12 PF04757.9 EXF74034.1 - 2.8e-40 138.1 2.7 2.8e-40 138.1 1.9 1.4 2 0 0 2 2 2 1 Pex2 / Pex12 amino terminal region zf-C3HC4_4 PF15227.1 EXF74034.1 - 0.00015 21.6 4.6 0.00029 20.6 3.2 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EXF74034.1 - 0.023 14.7 4.9 0.023 14.7 3.4 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EXF74034.1 - 0.053 13.1 3.4 0.13 11.9 2.3 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EXF74034.1 - 0.077 12.7 2.2 0.083 12.6 0.2 1.9 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.1 EXF74034.1 - 0.17 11.7 4.7 1.3 8.8 0.8 2.4 2 0 0 2 2 2 0 Ring finger domain MFS_1_like PF12832.2 EXF74035.1 - 5.6e-15 54.9 0.1 5.6e-15 54.9 0.0 2.9 2 0 0 2 2 2 1 MFS_1 like family Pribosyltran PF00156.22 EXF74036.1 - 6.7e-18 64.6 0.0 1.2e-17 63.8 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EXF74036.1 - 0.0019 17.4 0.0 0.0026 16.9 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Epimerase PF01370.16 EXF74037.1 - 2.4e-10 40.2 0.0 0.00025 20.5 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF74037.1 - 9.8e-05 22.4 0.0 0.00068 19.6 0.0 2.2 3 0 0 3 3 3 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EXF74037.1 - 0.00013 22.2 0.1 0.0003 21.0 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 EXF74037.1 - 0.0015 17.8 0.0 0.003 16.8 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EXF74037.1 - 0.0027 16.4 0.0 0.6 8.7 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EXF74037.1 - 0.013 14.4 0.0 0.14 11.0 0.0 2.2 1 1 0 1 1 1 0 Male sterility protein RmlD_sub_bind PF04321.12 EXF74037.1 - 0.027 13.3 0.2 0.54 9.1 0.1 2.3 2 0 0 2 2 2 0 RmlD substrate binding domain Raffinose_syn PF05691.7 EXF74038.1 - 1.6e-55 187.9 5.1 4.2e-50 170.0 2.7 3.1 2 1 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 Glyco_hydro_31 PF01055.21 EXF74038.1 - 1.7e-06 27.1 1.3 2.5e-06 26.6 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Melibiase PF02065.13 EXF74038.1 - 0.00031 19.5 1.7 0.0005 18.8 1.2 1.2 1 0 0 1 1 1 1 Melibiase Peptidase_M16 PF00675.15 EXF74039.1 - 4e-57 192.1 1.6 4.8e-57 191.8 0.3 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EXF74039.1 - 9.6e-39 132.9 0.1 5.9e-38 130.3 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain Esterase PF00756.15 EXF74039.1 - 0.0034 16.8 0.0 0.0069 15.8 0.0 1.5 1 0 0 1 1 1 1 Putative esterase F-actin_cap_A PF01267.12 EXF74039.1 - 0.021 13.9 0.0 0.036 13.1 0.0 1.4 1 0 0 1 1 1 0 F-actin capping protein alpha subunit Histidinol_dh PF00815.15 EXF74040.1 - 2.2e-179 596.4 5.4 2.2e-179 596.4 3.7 1.5 2 0 0 2 2 2 1 Histidinol dehydrogenase PRA-CH PF01502.13 EXF74040.1 - 5.2e-25 86.8 0.0 1e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.12 EXF74040.1 - 1e-10 41.7 0.8 2.9e-10 40.2 0.1 2.1 2 0 0 2 2 2 1 Phosphoribosyl-ATP pyrophosphohydrolase Phasin_2 PF09361.5 EXF74040.1 - 2.4 8.2 5.6 1.8 8.6 0.3 3.4 4 0 0 4 4 4 0 Phasin protein TFIID-31kDa PF02291.10 EXF74041.1 - 8e-27 93.5 0.0 1.3e-25 89.6 0.0 2.1 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit PIH1 PF08190.7 EXF74041.1 - 4.8 6.5 9.9 7 5.9 6.9 1.2 1 0 0 1 1 1 0 pre-RNA processing PIH1/Nop17 ORC6 PF05460.8 EXF74041.1 - 10 5.1 12.5 15 4.5 8.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) LNS2 PF08235.8 EXF74042.1 - 3.3e-70 234.7 0.0 5.5e-70 233.9 0.0 1.4 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EXF74042.1 - 1.2e-39 134.3 0.0 3.3e-38 129.7 0.0 2.5 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.9 EXF74042.1 - 0.0035 16.7 0.3 0.15 11.3 0.0 2.7 3 0 0 3 3 3 1 HAD superfamily, subfamily IIIB (Acid phosphatase) Nop14 PF04147.7 EXF74042.1 - 3.9 5.2 24.2 6.1 4.6 16.8 1.1 1 0 0 1 1 1 0 Nop14-like family UDPGP PF01704.13 EXF74043.1 - 5.7e-55 186.5 0.0 7.3e-55 186.1 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EXF74043.1 - 0.0097 16.0 0.0 0.046 13.7 0.0 2.0 2 0 0 2 2 2 1 MobA-like NTP transferase domain fn3 PF00041.16 EXF74044.1 - 3.4e-08 33.4 0.0 9.6e-08 32.0 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain Cmc1 PF08583.5 EXF74045.1 - 7.8e-18 64.0 1.7 7.8e-18 64.0 1.2 1.9 3 0 0 3 3 3 1 Cytochrome c oxidase biogenesis protein Cmc1 like CHCH PF06747.8 EXF74045.1 - 0.014 15.3 0.1 0.1 12.5 0.1 2.1 1 1 1 2 2 2 0 CHCH domain DUF3128 PF11326.3 EXF74045.1 - 0.023 14.7 5.8 0.19 11.9 1.7 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3128) AlaDh_PNT_N PF05222.10 EXF74046.1 - 1.1e-28 99.8 0.0 2.5e-28 98.7 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EXF74046.1 - 1.9e-11 43.8 0.0 4.9e-11 42.4 0.0 1.6 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 EXF74047.1 - 3.5e-26 91.9 0.0 4.6e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF74047.1 - 2.2e-05 24.4 0.0 5.7e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF74047.1 - 3.9e-05 22.6 0.0 5.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EXF74047.1 - 9.5e-05 22.3 0.1 0.00025 21.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EXF74047.1 - 9.8e-05 22.6 0.0 0.0002 21.6 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EXF74047.1 - 0.0003 20.2 0.0 0.00046 19.6 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EXF74047.1 - 0.00033 20.0 0.2 0.00052 19.4 0.1 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.1 EXF74047.1 - 0.0036 17.5 0.0 0.0055 16.9 0.0 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding 3HCDH_N PF02737.13 EXF74047.1 - 0.0065 16.1 0.0 0.0087 15.7 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EXF74047.1 - 0.0094 15.9 0.0 0.016 15.2 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_3 PF01494.14 EXF74047.1 - 0.012 14.6 0.1 0.018 14.1 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EXF74047.1 - 0.037 12.4 0.3 0.051 12.0 0.2 1.1 1 0 0 1 1 1 0 HI0933-like protein F420_oxidored PF03807.12 EXF74047.1 - 0.045 14.1 0.0 0.087 13.2 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EXF74047.1 - 0.05 13.4 0.0 0.088 12.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase GIDA PF01134.17 EXF74047.1 - 0.052 12.4 0.1 0.068 12.0 0.0 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A Thi4 PF01946.12 EXF74047.1 - 0.063 12.3 0.2 0.12 11.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_10 PF13460.1 EXF74047.1 - 0.11 12.5 0.1 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Pyr_redox_3 PF13738.1 EXF74047.1 - 0.14 12.1 0.0 0.57 10.1 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Utp11 PF03998.8 EXF74049.1 - 2.2e-59 201.2 16.5 2.6e-59 201.0 11.4 1.0 1 0 0 1 1 1 1 Utp11 protein SURF2 PF05477.6 EXF74049.1 - 0.63 9.1 9.0 0.085 11.9 2.5 2.0 1 1 1 2 2 2 0 Surfeit locus protein 2 (SURF2) FlxA PF14282.1 EXF74049.1 - 1.2 9.1 7.1 0.41 10.6 1.0 2.8 4 0 0 4 4 4 0 FlxA-like protein Fmp27_WPPW PF10359.4 EXF74049.1 - 6.7 4.9 10.6 1.2 7.4 1.1 2.2 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Glyco_hydro_47 PF01532.15 EXF74050.1 - 5.8e-164 546.0 0.2 6.7e-164 545.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF1680 PF07944.7 EXF74050.1 - 0.026 12.7 0.2 0.61 8.2 0.0 2.4 2 1 0 2 2 2 0 Putative glycosyl hydrolase of unknown function (DUF1680) Maf PF02545.9 EXF74051.1 - 2.2e-45 154.1 0.0 2.9e-45 153.8 0.0 1.1 1 0 0 1 1 1 1 Maf-like protein HLH PF00010.21 EXF74052.1 - 2.8e-08 33.3 0.0 4.7e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Umbravirus_LDM PF04817.7 EXF74052.1 - 0.0067 15.5 0.3 0.0074 15.4 0.2 1.1 1 0 0 1 1 1 1 Umbravirus long distance movement (LDM) family tRNA-synt_2b PF00587.20 EXF74053.1 - 1.8e-46 157.8 0.0 2.6e-46 157.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EXF74053.1 - 1.4e-09 37.8 0.0 5.9e-09 35.7 0.0 1.9 2 0 0 2 2 2 1 Anticodon binding domain Basic PF01586.11 EXF74053.1 - 0.13 12.9 0.4 0.32 11.7 0.3 1.6 1 0 0 1 1 1 0 Myogenic Basic domain Aldedh PF00171.17 EXF74054.1 - 5.6e-137 456.8 1.6 6.7e-137 456.5 1.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EXF74054.1 - 7.9e-05 21.5 0.1 0.00013 20.7 0.0 1.4 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) Zn_clus PF00172.13 EXF74056.1 - 1.5e-05 24.8 10.4 1.5e-05 24.8 7.2 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAM-associated PF14303.1 EXF74056.1 - 0.13 12.5 1.7 0.21 11.8 1.2 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain OPA3 PF07047.7 EXF74062.1 - 4.4e-36 123.6 11.1 3.9e-35 120.5 7.7 2.6 1 1 0 1 1 1 1 Optic atrophy 3 protein (OPA3) FimP PF09766.4 EXF74062.1 - 0.0016 17.5 3.7 0.0016 17.5 2.6 2.1 2 0 0 2 2 2 1 Fms-interacting protein TMF_DNA_bd PF12329.3 EXF74062.1 - 0.011 15.5 6.2 0.011 15.5 4.3 2.6 2 1 0 2 2 1 0 TATA element modulatory factor 1 DNA binding DUF4303 PF14136.1 EXF74062.1 - 0.013 15.1 0.3 0.033 13.8 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4303) PDE6_gamma PF04868.7 EXF74062.1 - 0.016 15.0 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 Retinal cGMP phosphodiesterase, gamma subunit SPX PF03105.14 EXF74062.1 - 0.029 14.1 12.3 0.076 12.7 0.9 2.2 2 0 0 2 2 2 0 SPX domain MFMR PF07777.6 EXF74062.1 - 0.1 12.5 10.2 0.19 11.6 7.1 1.5 1 0 0 1 1 1 0 G-box binding protein MFMR RAP1 PF07218.6 EXF74062.1 - 0.16 10.0 6.4 0.16 10.0 4.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ADIP PF11559.3 EXF74062.1 - 0.52 10.1 18.4 0.18 11.7 3.7 2.2 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Herpes_capsid PF06112.6 EXF74062.1 - 0.67 9.9 13.8 1.4 8.9 9.6 1.5 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Mem_trans PF03547.13 EXF74062.1 - 0.72 8.0 6.7 1.2 7.4 4.6 1.2 1 0 0 1 1 1 0 Membrane transport protein Matrilin_ccoil PF10393.4 EXF74062.1 - 1.2 8.5 8.2 0.48 9.8 0.8 3.2 3 1 1 4 4 4 0 Trimeric coiled-coil oligomerisation domain of matrilin Peptidase_S49_N PF08496.5 EXF74062.1 - 1.5 8.6 6.3 18 5.0 2.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF724 PF05266.9 EXF74062.1 - 2.1 7.8 11.7 0.42 10.2 1.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) APG6 PF04111.7 EXF74062.1 - 4.9 6.0 13.2 1.5 7.8 2.2 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Ribosomal_L12 PF00542.14 EXF74062.1 - 6.6 6.8 16.3 0.57 10.2 7.3 2.2 3 0 0 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain FadA PF09403.5 EXF74062.1 - 7 6.6 16.3 0.16 11.9 0.9 2.4 2 1 0 2 2 2 0 Adhesion protein FadA BTV_NS2 PF04514.7 EXF74062.1 - 9.6 4.9 10.4 9.9 4.9 1.9 2.1 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Pkinase PF00069.20 EXF74063.1 - 1.8e-65 220.6 0.0 2.6e-65 220.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF74063.1 - 3.4e-42 144.3 0.0 4.7e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF74063.1 - 1.1e-07 31.1 0.0 1.7e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like POLO_box PF00659.13 EXF74063.1 - 5.4e-06 26.2 0.0 0.0018 18.2 0.0 3.0 2 0 0 2 2 2 1 POLO box duplicated region Kdo PF06293.9 EXF74063.1 - 0.0022 17.1 0.0 0.0047 16.0 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Rav1p_C PF12234.3 EXF74063.1 - 0.41 8.7 0.2 0.61 8.1 0.1 1.2 1 0 0 1 1 1 0 RAVE protein 1 C terminal ketoacyl-synt PF00109.21 EXF74064.1 - 4.6e-77 258.9 0.0 1.3e-76 257.4 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EXF74064.1 - 5.5e-50 170.4 0.8 8.9e-50 169.8 0.1 1.6 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.5 EXF74064.1 - 3.7e-48 163.5 0.2 1.3e-47 161.8 0.0 2.1 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 EXF74064.1 - 3.3e-46 157.7 0.0 6.6e-46 156.8 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EXF74064.1 - 6.2e-38 130.3 0.0 1.8e-37 128.8 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase Condensation PF00668.15 EXF74064.1 - 1.4e-36 125.9 0.0 2.7e-36 124.9 0.0 1.5 1 0 0 1 1 1 1 Condensation domain Ketoacyl-synt_C PF02801.17 EXF74064.1 - 6e-31 106.7 0.1 1.6e-30 105.3 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EXF74064.1 - 8.5e-19 67.8 0.0 3.4e-18 65.9 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF74064.1 - 9.1e-15 54.7 0.0 2e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF74064.1 - 7.8e-10 39.1 0.0 2.1e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF74064.1 - 7.8e-10 38.5 0.0 1.8e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EXF74064.1 - 2.7e-05 23.2 0.0 5.6e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 EXF74064.1 - 3.1e-05 24.1 0.0 9.1e-05 22.6 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.1 EXF74064.1 - 8.6e-05 22.8 0.0 0.00036 20.8 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain HxxPF_rpt PF13745.1 EXF74064.1 - 0.00071 19.8 0.0 0.002 18.3 0.0 1.8 1 0 0 1 1 1 1 HxxPF-repeated domain Ubie_methyltran PF01209.13 EXF74064.1 - 0.00076 18.6 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family F420_oxidored PF03807.12 EXF74064.1 - 0.029 14.8 0.2 0.24 11.8 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ACP_syn_III PF08545.5 EXF74064.1 - 0.032 13.8 0.1 0.16 11.6 0.1 2.3 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_16 PF10294.4 EXF74064.1 - 0.036 13.5 0.0 0.11 11.9 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase NodS PF05401.6 EXF74064.1 - 0.09 12.1 0.0 0.19 11.0 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF3328 PF11807.3 EXF74065.1 - 1.8e-29 103.0 5.8 1.8e-29 103.0 4.0 1.6 1 1 0 2 2 2 1 Domain of unknown function (DUF3328) ADH_N PF08240.7 EXF74066.1 - 3.1e-10 39.7 0.2 1.1e-09 38.0 0.1 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF74066.1 - 2.7e-07 30.1 0.0 5.4e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FSH1 PF03959.8 EXF74067.1 - 1.9e-33 115.6 0.0 2.4e-33 115.3 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EXF74067.1 - 5.5e-08 32.6 0.4 8.8e-08 32.0 0.3 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EXF74067.1 - 0.00011 21.7 0.4 0.00046 19.6 0.3 1.8 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EXF74067.1 - 0.0016 18.3 1.4 0.99 9.2 0.2 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EXF74067.1 - 0.11 11.9 0.3 1.1 8.6 0.0 2.1 1 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) p450 PF00067.17 EXF74068.1 - 2.2e-55 188.0 0.0 2.5e-55 187.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PhyH PF05721.8 EXF74070.1 - 3.4e-19 69.7 0.0 5.4e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) APH PF01636.18 EXF74071.1 - 2.3e-09 37.3 0.1 3.1e-09 36.9 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EXF74071.1 - 0.011 14.8 0.0 0.017 14.2 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Choline_kinase PF01633.15 EXF74071.1 - 0.17 11.4 0.0 0.34 10.4 0.0 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase AMP-binding PF00501.23 EXF74072.1 - 2.7e-22 78.7 0.0 3.5e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MFS_1 PF07690.11 EXF74073.1 - 0.00023 19.9 0.2 0.00037 19.3 0.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Virul_fac_BrkB PF03631.10 EXF74073.1 - 0.28 10.4 4.2 0.098 11.9 0.5 1.8 2 0 0 2 2 2 0 Virulence factor BrkB MFS_2 PF13347.1 EXF74074.1 - 3.7e-11 42.0 9.4 3.7e-11 42.0 6.5 2.2 2 0 0 2 2 2 1 MFS/sugar transport protein DUF3328 PF11807.3 EXF74075.1 - 2e-40 138.8 0.0 2.4e-40 138.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EXF74076.1 - 7e-31 107.6 3.0 9.5e-31 107.1 2.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Sel1 PF08238.7 EXF74077.1 - 1.6e-36 123.9 30.6 4.9e-05 23.8 0.1 7.6 7 0 0 7 7 7 7 Sel1 repeat Chitin_synth_2 PF03142.10 EXF74078.1 - 1.6e-293 973.9 1.1 2e-293 973.5 0.1 1.6 2 0 0 2 2 2 1 Chitin synthase Glyco_trans_2_3 PF13632.1 EXF74078.1 - 6.2e-18 65.1 5.6 3.2e-17 62.8 3.8 2.1 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EXF74078.1 - 3e-15 56.6 0.0 2.1e-14 53.8 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Cyt-b5 PF00173.23 EXF74078.1 - 1.8e-14 53.2 0.1 1.7e-10 40.5 0.0 2.5 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_transf_21 PF13506.1 EXF74078.1 - 1.4e-05 24.4 0.0 0.00064 19.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EXF74078.1 - 0.011 15.4 0.0 0.036 13.7 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferase family 2 UBA_e1_C PF09358.5 EXF74079.1 - 0.2 11.7 0.1 0.41 10.8 0.1 1.4 1 0 0 1 1 1 0 Ubiquitin-activating enzyme e1 C-terminal domain E1-E2_ATPase PF00122.15 EXF74081.1 - 1.2e-62 210.9 7.3 2.7e-62 209.8 5.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EXF74081.1 - 1e-22 81.5 0.0 3.2e-22 80.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EXF74081.1 - 8.1e-13 48.9 0.0 2.4e-12 47.3 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EXF74081.1 - 1.3e-08 34.1 0.1 2.8e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EXF74081.1 - 0.0012 18.4 0.1 0.0028 17.2 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EXF74081.1 - 0.038 13.9 0.0 0.074 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit Arrestin_C PF02752.17 EXF74082.1 - 0.032 14.3 0.0 0.038 14.0 0.0 1.2 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain DUF3425 PF11905.3 EXF74085.1 - 1.3e-31 109.2 3.4 2.4e-31 108.4 2.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EXF74085.1 - 0.0046 16.8 7.8 0.0046 16.8 5.4 2.2 1 1 1 2 2 2 1 bZIP transcription factor DUF390 PF04094.9 EXF74085.1 - 8.9 4.2 13.1 3 5.7 6.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF390) Spindle_Spc25 PF08234.7 EXF74086.1 - 6e-22 77.4 0.9 9.1e-22 76.8 0.0 1.8 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 VRP1 PF03538.9 EXF74086.1 - 0.001 18.2 1.6 0.0018 17.4 0.4 1.7 1 1 0 2 2 2 1 Salmonella virulence plasmid 28.1kDa A protein Filament PF00038.16 EXF74086.1 - 0.062 12.7 18.9 0.21 11.0 13.1 1.8 1 1 0 1 1 1 0 Intermediate filament protein THOC7 PF05615.8 EXF74086.1 - 0.13 12.5 14.4 0.02 15.1 6.4 2.1 2 1 0 2 2 2 0 Tho complex subunit 7 DUF342 PF03961.8 EXF74086.1 - 0.18 10.1 8.0 0.25 9.7 5.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Hid1 PF12722.2 EXF74086.1 - 0.45 8.1 5.4 0.39 8.3 3.0 1.4 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein Atg14 PF10186.4 EXF74086.1 - 0.86 8.4 16.5 0.28 10.0 9.6 1.5 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Mnd1 PF03962.10 EXF74086.1 - 1.4 8.5 18.8 4.4 6.9 5.8 2.3 1 1 1 2 2 2 0 Mnd1 family Striatin PF08232.7 EXF74086.1 - 4.7 7.5 19.8 1.9 8.8 6.6 2.4 1 1 1 2 2 2 0 Striatin family V_ATPase_I PF01496.14 EXF74086.1 - 5.3 4.7 8.5 6.4 4.4 5.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FUSC PF04632.7 EXF74086.1 - 5.4 5.3 6.9 7.2 4.9 4.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF848 PF05852.6 EXF74086.1 - 8.1 6.2 17.0 1 9.1 6.2 2.7 2 1 1 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) TMPIT PF07851.8 EXF74086.1 - 8.5 5.3 11.5 13 4.7 8.0 1.2 1 0 0 1 1 1 0 TMPIT-like protein MFS_1 PF07690.11 EXF74087.1 - 4.6e-19 68.3 20.8 4.6e-19 68.3 14.4 2.8 1 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF74087.1 - 2.8e-09 36.0 17.1 3.1e-05 22.7 0.1 3.4 3 1 0 3 3 3 3 Sugar (and other) transporter Neurensin PF14927.1 EXF74087.1 - 0.085 12.2 3.2 0.086 12.2 0.8 2.1 2 0 0 2 2 2 0 Neurensin SPX PF03105.14 EXF74088.1 - 8.1e-49 166.8 0.0 1.9e-48 165.6 0.0 1.6 1 1 0 1 1 1 1 SPX domain Na_sulph_symp PF00939.14 EXF74088.1 - 1.9e-36 125.9 40.6 2.8e-36 125.4 28.2 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.11 EXF74088.1 - 1.9e-12 46.4 51.0 2e-11 43.1 22.0 2.9 1 1 2 3 3 3 3 Citrate transporter Sporozoite_P67 PF05642.6 EXF74088.1 - 0.015 13.1 1.9 0.027 12.3 1.3 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Asp_Arg_Hydrox PF05118.10 EXF74088.1 - 0.16 11.8 1.0 0.36 10.6 0.7 1.6 1 0 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase Vps39_1 PF10366.4 EXF74089.1 - 3.3e-33 113.9 0.0 3.4e-32 110.6 0.0 2.9 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 1 Vps39_2 PF10367.4 EXF74089.1 - 8.4e-31 106.3 0.0 2.6e-30 104.8 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.17 EXF74089.1 - 1.8e-21 76.8 0.0 3.5e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 CNH domain Clathrin PF00637.15 EXF74089.1 - 2e-07 30.7 0.9 0.00028 20.5 0.5 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS DUF3893 PF13032.1 EXF74089.1 - 0.016 15.3 0.1 0.051 13.6 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3893) Apc3 PF12895.2 EXF74089.1 - 0.049 13.7 1.2 3.5 7.8 0.0 3.4 2 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EXF74089.1 - 0.89 9.2 6.2 4.2 7.1 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat Gon7 PF08738.5 EXF74090.1 - 3.8e-13 49.3 6.2 1.9e-11 43.8 4.3 2.1 1 1 0 1 1 1 1 Gon7 family DUF3987 PF13148.1 EXF74090.1 - 0.029 12.9 1.3 0.029 12.9 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) HbrB PF08539.6 EXF74091.1 - 1.9e-55 187.0 0.0 2.9e-55 186.4 0.0 1.3 1 0 0 1 1 1 1 HbrB-like BAF1_ABF1 PF04684.8 EXF74091.1 - 2.2 7.0 33.4 0.77 8.5 5.0 2.5 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor LIM_bind PF01803.11 EXF74092.1 - 4.9e-81 271.3 0.0 4.9e-81 271.3 0.0 4.2 2 1 1 3 3 3 1 LIM-domain binding protein Metallophos PF00149.23 EXF74093.1 - 8.1e-08 31.9 3.9 0.00015 21.2 0.1 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EXF74093.1 - 0.00011 22.1 0.1 0.00028 20.7 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF688 PF05097.7 EXF74093.1 - 0.03 13.2 0.9 0.072 12.0 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF688) NOA36 PF06524.7 EXF74093.1 - 5.8 6.0 6.3 11 5.1 4.3 1.3 1 0 0 1 1 1 0 NOA36 protein SNARE PF05739.14 EXF74094.1 - 7.3e-13 47.9 2.6 1.6e-12 46.9 1.5 1.8 2 0 0 2 2 2 1 SNARE domain WD40 PF00400.27 EXF74095.1 - 5.1e-11 41.9 2.4 7.2e-07 28.8 0.1 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat PPTA PF01239.17 EXF74096.1 - 1.7e-37 125.2 13.8 3.1e-07 29.4 0.3 5.6 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat His_Phos_2 PF00328.17 EXF74097.1 - 9.7e-05 21.8 0.0 0.013 14.8 0.0 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) SBP_bac_10 PF07596.6 EXF74097.1 - 0.00079 19.5 0.0 0.0027 17.7 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1559) HSP70 PF00012.15 EXF74099.1 - 2.8e-10 38.7 0.4 1.9e-09 36.0 0.1 1.9 2 0 0 2 2 2 1 Hsp70 protein zf-SAP30 PF13866.1 EXF74099.1 - 0.0049 16.4 0.1 0.011 15.3 0.1 1.5 1 0 0 1 1 1 1 SAP30 zinc-finger MreB_Mbl PF06723.8 EXF74099.1 - 0.014 14.0 0.1 0.063 11.8 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein Thaumatin PF00314.12 EXF74100.1 - 3.3e-68 229.3 4.4 4.4e-68 228.9 3.1 1.2 1 0 0 1 1 1 1 Thaumatin family PTCB-BRCT PF12738.2 EXF74101.1 - 0.00053 19.7 0.2 0.0016 18.2 0.0 1.9 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 EXF74101.1 - 0.0046 17.0 0.0 0.01 15.9 0.0 1.6 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Ribosomal_60s PF00428.14 EXF74101.1 - 0.079 13.3 1.9 0.38 11.1 1.5 1.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein AMP-binding PF00501.23 EXF74102.1 - 3.4e-77 259.5 0.0 4.2e-77 259.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EXF74102.1 - 1.4e-15 58.0 0.0 4.7e-15 56.3 0.0 2.0 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ADH_zinc_N PF00107.21 EXF74104.1 - 2.8e-26 91.5 0.1 4.8e-26 90.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF74104.1 - 7.7e-18 65.6 0.0 1.6e-17 64.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF74104.1 - 8.3e-11 41.6 0.0 6.9e-10 38.6 0.0 2.2 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CFEM PF05730.6 EXF74105.1 - 2.4e-07 30.4 3.6 2.4e-07 30.4 2.5 1.7 2 0 0 2 2 2 1 CFEM domain DLH PF01738.13 EXF74106.1 - 7.4e-21 74.4 0.0 3.1e-09 36.4 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EXF74106.1 - 2.2e-10 40.4 0.0 3.4e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF74106.1 - 0.00017 21.5 0.0 0.049 13.5 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EXF74106.1 - 0.074 12.6 0.0 0.22 11.0 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Rep_fac-A_C PF08646.5 EXF74107.1 - 1.3e-55 187.1 4.6 3.7e-54 182.3 2.2 2.5 2 0 0 2 2 2 2 Replication factor-A C terminal domain Rep-A_N PF04057.7 EXF74107.1 - 1.8e-24 85.4 0.1 4.3e-24 84.2 0.1 1.7 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.20 EXF74107.1 - 1.6e-16 59.8 0.8 6.9e-11 41.8 0.0 4.3 4 1 1 5 5 5 2 OB-fold nucleic acid binding domain PCI PF01399.22 EXF74108.1 - 0.014 15.6 0.1 0.098 12.9 0.0 2.3 2 0 0 2 2 2 0 PCI domain Amidohydro_4 PF13147.1 EXF74109.1 - 1.1e-07 32.2 1.2 1.5e-07 31.7 0.9 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_2 PF04909.9 EXF74109.1 - 5e-06 26.2 0.1 9.9e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EXF74109.1 - 9.2e-06 25.5 0.2 1.3e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Amidohydrolase family TatD_DNase PF01026.16 EXF74109.1 - 0.012 14.7 0.2 0.031 13.4 0.1 1.6 1 1 0 1 1 1 0 TatD related DNase DUF4434 PF14488.1 EXF74110.1 - 0.039 13.6 0.1 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4434) zf-PHD-like PF15446.1 EXF74111.1 - 1e-70 236.5 11.3 2.7e-70 235.1 7.8 1.8 1 0 0 1 1 1 1 PHD/FYVE-zinc-finger like domain SNF2_N PF00176.18 EXF74111.1 - 1.3e-57 194.9 0.0 1.8e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HDA2-3 PF11496.3 EXF74111.1 - 3.3e-16 58.9 1.6 7.4e-16 57.8 1.1 1.5 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Helicase_C PF00271.26 EXF74111.1 - 1.9e-15 56.4 0.0 7e-15 54.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.19 EXF74111.1 - 1.7e-06 27.5 1.2 0.00018 21.1 0.5 3.1 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain PHD PF00628.24 EXF74111.1 - 1.2e-05 24.8 2.2 1.2e-05 24.8 1.5 3.6 3 1 1 4 4 4 2 PHD-finger DEAD PF00270.24 EXF74111.1 - 0.0004 19.9 0.0 0.00074 19.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase PHD_2 PF13831.1 EXF74111.1 - 0.0005 19.3 0.4 0.0005 19.3 0.3 3.1 3 0 0 3 3 3 1 PHD-finger SpoU_methylase PF00588.14 EXF74112.1 - 6.4e-28 97.4 0.0 1e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EXF74112.1 - 3.9e-10 39.7 0.0 1.2e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding Arginase PF00491.16 EXF74115.1 - 3.9e-89 298.6 0.0 4.9e-89 298.3 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EXF74115.1 - 0.12 12.6 0.0 0.24 11.5 0.0 1.5 1 1 0 1 1 1 0 UPF0489 domain DUF1589 PF07628.6 EXF74115.1 - 0.13 12.1 0.0 0.6 10.0 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1589) zf-U1 PF06220.7 EXF74117.1 - 5.2e-22 77.1 3.4 7.7e-22 76.5 2.3 1.3 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EXF74117.1 - 0.02 14.9 3.6 0.045 13.9 2.5 1.6 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding EMP24_GP25L PF01105.19 EXF74118.1 - 1.7e-42 145.2 0.0 2.1e-42 144.9 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF4164 PF13747.1 EXF74118.1 - 0.041 14.0 0.9 0.064 13.3 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) EzrA PF06160.7 EXF74118.1 - 0.054 11.6 0.2 0.068 11.3 0.2 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Sdh5 PF03937.11 EXF74119.1 - 6.7e-23 80.1 0.3 1.7e-22 78.8 0.1 1.7 2 0 0 2 2 2 1 Flavinator of succinate dehydrogenase RAP1 PF07218.6 EXF74119.1 - 0.45 8.5 5.2 0.56 8.2 3.6 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MIS13 PF08202.6 EXF74120.1 - 3.8e-60 203.5 2.4 7.5e-60 202.5 1.7 1.5 1 0 0 1 1 1 1 Mis12-Mtw1 protein family RNA_pol_Rpb4 PF03874.11 EXF74120.1 - 0.041 13.8 0.6 0.12 12.3 0.4 1.9 1 1 0 1 1 1 0 RNA polymerase Rpb4 Aft1_HRA PF11786.3 EXF74121.1 - 1.8e-30 105.0 9.5 1.8e-30 105.0 6.6 3.1 4 0 0 4 4 4 1 Aft1 HRA domain Aft1_OSA PF11785.3 EXF74121.1 - 1.4e-18 67.1 5.7 1.4e-18 67.1 3.9 5.9 6 0 0 6 6 6 1 Aft1 osmotic stress response (OSM) domain Aft1_HRR PF11787.3 EXF74121.1 - 3.1e-16 60.1 22.1 3.1e-16 60.1 15.3 4.1 5 1 0 5 5 5 1 Aft1 HRR domain bZIP_1 PF00170.16 EXF74121.1 - 2.2e-13 49.9 6.1 3.8e-13 49.1 4.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EXF74121.1 - 1.5e-06 27.9 6.1 1.5e-06 27.9 4.2 1.8 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EXF74121.1 - 0.0023 18.1 2.9 0.0023 18.1 2.0 2.3 2 0 0 2 2 2 1 bZIP Maf transcription factor DUF1043 PF06295.7 EXF74121.1 - 0.26 10.9 3.8 0.66 9.6 2.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Dala_Dala_lig_N PF01820.16 EXF74121.1 - 0.48 10.7 3.1 0.37 11.0 0.4 2.0 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus DUF4407 PF14362.1 EXF74121.1 - 4.6 6.1 8.2 5.8 5.7 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) GST_N_3 PF13417.1 EXF74122.1 - 2.2e-11 43.7 0.3 4.2e-11 42.9 0.2 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EXF74122.1 - 2.5e-05 24.0 0.2 4.7e-05 23.1 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EXF74122.1 - 9e-05 22.8 0.0 0.00015 22.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EXF74122.1 - 0.00064 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EXF74122.1 - 0.0019 18.1 0.0 0.0057 16.6 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain p450 PF00067.17 EXF74123.1 - 1e-45 156.1 0.0 1.8e-38 132.2 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 MBF1 PF08523.5 EXF74125.1 - 5.4e-26 90.4 2.2 1.1e-25 89.4 1.5 1.5 1 0 0 1 1 1 1 Multiprotein bridging factor 1 HTH_3 PF01381.17 EXF74125.1 - 7e-11 41.8 0.0 1.2e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix HTH_19 PF12844.2 EXF74125.1 - 0.00026 20.9 0.0 0.00038 20.4 0.0 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 EXF74125.1 - 0.003 17.7 0.0 0.0055 16.8 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain MRP-L27 PF09809.4 EXF74125.1 - 0.018 14.6 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L27 HTH_24 PF13412.1 EXF74125.1 - 0.12 11.8 0.0 0.53 9.7 0.0 1.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding WLM PF08325.5 EXF74127.1 - 2.9e-49 167.4 0.0 4.8e-49 166.7 0.0 1.4 1 0 0 1 1 1 1 WLM domain Peptidase_M54 PF07998.6 EXF74127.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M54 DUF45 PF01863.12 EXF74127.1 - 0.93 9.2 3.3 0.4 10.4 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF45 Asp PF00026.18 EXF74128.1 - 2.4e-69 233.9 8.8 2.8e-69 233.7 6.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EXF74128.1 - 7.7e-07 29.1 3.6 1e-06 28.8 1.1 2.3 1 1 1 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EXF74128.1 - 0.0037 17.7 2.2 0.11 13.0 0.4 3.0 2 2 0 2 2 2 1 Aspartyl protease PLA2_B PF01735.13 EXF74130.1 - 1.3e-192 640.3 0.2 1.6e-192 640.1 0.1 1.0 1 0 0 1 1 1 1 Lysophospholipase catalytic domain PTCB-BRCT PF12738.2 EXF74131.1 - 0.057 13.2 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 twin BRCT domain BRCT PF00533.21 EXF74131.1 - 0.067 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain HHH_8 PF14716.1 EXF74133.1 - 0.051 13.7 1.6 0.061 13.5 0.4 1.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain DAHP_synth_2 PF01474.11 EXF74134.1 - 2.2e-192 639.3 0.0 2.5e-192 639.1 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family Amidase PF01425.16 EXF74135.1 - 1.8e-90 303.8 0.0 2.3e-90 303.5 0.0 1.1 1 0 0 1 1 1 1 Amidase Methyltransf_31 PF13847.1 EXF74136.1 - 3e-14 52.8 0.0 4e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF74136.1 - 5.5e-10 39.8 0.0 1e-09 38.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF74136.1 - 2.2e-08 34.4 0.0 9.6e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF74136.1 - 2.6e-07 31.0 0.0 5.2e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EXF74136.1 - 3e-07 30.1 0.3 5.9e-07 29.2 0.0 1.5 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 EXF74136.1 - 2.3e-06 27.9 0.0 4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF74136.1 - 3.1e-06 27.0 0.0 4.4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF74136.1 - 5e-06 26.5 0.0 1.1e-05 25.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EXF74136.1 - 1e-05 25.2 0.1 2.6e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 MTS PF05175.9 EXF74136.1 - 1.9e-05 24.1 0.0 3.1e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EXF74136.1 - 0.00042 19.4 0.0 0.0006 18.9 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.1 EXF74136.1 - 0.00058 19.5 0.0 0.00084 19.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EXF74136.1 - 0.0018 17.4 0.2 0.0028 16.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 EXF74136.1 - 0.0065 15.5 0.0 0.0089 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.12 EXF74136.1 - 0.044 12.8 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_9 PF08003.6 EXF74136.1 - 0.065 11.9 0.0 0.1 11.2 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) NAD_binding_6 PF08030.7 EXF74137.1 - 1.2e-23 83.7 0.0 1.8e-23 83.1 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EXF74137.1 - 8.9e-23 80.1 0.0 2e-22 79.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EXF74137.1 - 3.6e-16 59.3 9.9 3.6e-16 59.3 6.9 1.9 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EXF74137.1 - 0.00016 21.7 0.0 0.00044 20.3 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NADH_u_ox_C PF12853.2 EXF74138.1 - 0.051 13.2 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit F-box-like PF12937.2 EXF74139.1 - 1.3e-08 34.4 0.5 2.4e-08 33.5 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EXF74139.1 - 2.1e-06 27.2 0.7 5.2e-06 25.9 0.5 1.7 1 0 0 1 1 1 1 F-box domain Myosin_head PF00063.16 EXF74140.1 - 6.9e-234 777.9 1.7 1.1e-233 777.3 1.2 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EXF74140.1 - 2.5e-38 131.3 0.0 8e-38 129.7 0.0 1.9 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 EXF74140.1 - 3.5e-13 48.7 0.2 7e-13 47.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EXF74140.1 - 5e-13 48.4 0.1 1.2e-12 47.2 0.1 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EXF74140.1 - 8.7e-10 37.9 0.0 3.9e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 Variant SH3 domain IQ PF00612.22 EXF74140.1 - 0.0015 17.9 9.7 0.041 13.5 1.7 2.7 1 1 1 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 EXF74140.1 - 0.0052 16.9 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EXF74140.1 - 0.019 14.0 0.0 0.046 12.8 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin Hpr_kinase_C PF07475.7 EXF74140.1 - 0.063 12.5 0.3 2.9 7.1 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain DUF552 PF04472.7 EXF74140.1 - 0.065 13.1 0.0 0.22 11.4 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF552) AAA_17 PF13207.1 EXF74140.1 - 0.071 13.9 0.0 0.21 12.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EXF74140.1 - 0.074 13.3 0.0 0.2 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EXF74140.1 - 0.12 12.0 0.0 0.3 10.7 0.0 1.7 1 0 0 1 1 1 0 NACHT domain zf-DHHC PF01529.15 EXF74141.1 - 1.5e-19 70.0 15.5 6.9e-11 41.8 0.6 2.4 2 1 0 2 2 2 2 DHHC palmitoyltransferase Glyco_transf_90 PF05686.7 EXF74142.1 - 4.4e-07 28.9 0.0 0.0005 18.8 0.0 3.3 2 1 0 2 2 2 2 Glycosyl transferase family 90 Aldose_epim PF01263.15 EXF74143.1 - 1.9e-38 132.2 0.0 2.4e-38 131.9 0.0 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase Rif1_N PF12231.3 EXF74144.1 - 3e-138 460.8 1.5 4.3e-138 460.3 1.0 1.3 1 0 0 1 1 1 1 Rap1-interacting factor 1 N terminal Neurochondrin PF05536.6 EXF74144.1 - 0.0024 16.2 0.1 0.0045 15.3 0.1 1.3 1 0 0 1 1 1 1 Neurochondrin Ric8 PF10165.4 EXF74145.1 - 6.9e-119 397.5 0.0 8.5e-119 397.2 0.0 1.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor synembryn Imm29 PF15575.1 EXF74145.1 - 0.053 13.1 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 Immunity protein 29 NUC130_3NT PF08158.7 EXF74145.1 - 0.17 12.2 0.5 17 5.7 0.1 3.1 3 0 0 3 3 3 0 NUC130/3NT domain AT_hook PF02178.14 EXF74146.1 - 0.029 14.0 6.4 0.11 12.1 4.4 2.1 1 0 0 1 1 1 0 AT hook motif SspB PF04386.8 EXF74146.1 - 4.8 6.7 6.4 0.82 9.2 0.3 2.0 2 0 0 2 2 2 0 Stringent starvation protein B PQ-loop PF04193.9 EXF74147.1 - 6.7e-21 73.5 4.2 2.3e-11 43.0 0.7 2.5 2 0 0 2 2 2 2 PQ loop repeat DUF3353 PF11833.3 EXF74147.1 - 0.078 12.4 3.8 0.13 11.6 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) SprT-like PF10263.4 EXF74149.1 - 5.5e-15 55.3 3.0 1.1e-14 54.3 2.1 1.5 1 0 0 1 1 1 1 SprT-like family Peptidase_M76 PF09768.4 EXF74149.1 - 0.025 14.0 0.0 0.042 13.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase M76 family SprT-like PF10263.4 EXF74150.1 - 0.018 14.6 0.0 0.025 14.2 0.0 1.7 1 1 0 1 1 1 0 SprT-like family NnrU PF07298.6 EXF74152.1 - 0.096 12.0 6.6 1.4 8.2 0.5 2.5 2 1 0 2 2 2 0 NnrU protein SPC12 PF06645.8 EXF74152.1 - 1.1 9.0 5.4 2 8.2 0.9 2.8 2 1 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Ycf4 PF02392.11 EXF74152.1 - 6 6.1 6.4 2.8 7.2 1.8 2.1 2 0 0 2 2 2 0 Ycf4 BNR PF02012.15 EXF74153.1 - 1.6e-10 39.1 44.7 0.41 10.6 0.0 11.6 11 0 0 11 11 11 7 BNR/Asp-box repeat CHB_HEX_C_1 PF13290.1 EXF74153.1 - 1.6e-05 24.6 3.0 0.043 13.5 0.0 3.4 4 0 0 4 4 4 2 Chitobiase/beta-hexosaminidase C-terminal domain DUF2561 PF10812.3 EXF74153.1 - 0.026 14.1 0.1 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Herpes_US9 PF06072.6 EXF74153.1 - 0.18 11.6 0.4 3.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Alphaherpesvirus tegument protein US9 Mago-bind PF09282.5 EXF74154.1 - 2.6e-14 52.4 2.4 4.7e-14 51.6 1.7 1.5 1 0 0 1 1 1 1 Mago binding Nucleo_P87 PF07267.6 EXF74154.1 - 0.3 9.7 3.1 0.29 9.7 2.1 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 RR_TM4-6 PF06459.7 EXF74154.1 - 0.31 10.8 8.3 0.47 10.3 5.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.1 EXF74154.1 - 1.1 8.1 6.9 1.2 7.9 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) U79_P34 PF03064.11 EXF74154.1 - 1.4 8.3 11.1 1.9 7.9 7.7 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF2201_N PF13203.1 EXF74154.1 - 3.3 6.8 7.7 4.3 6.4 5.3 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF4633 PF15464.1 EXF74154.1 - 6.6 6.6 6.8 1.5 8.6 2.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4633) E1-E2_ATPase PF00122.15 EXF74155.1 - 2.3e-60 203.4 1.8 2.3e-60 203.4 1.2 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EXF74155.1 - 1.5e-43 148.4 4.0 1.5e-43 148.4 2.8 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EXF74155.1 - 2.9e-27 96.5 0.0 1.6e-26 94.1 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EXF74155.1 - 5.6e-20 71.0 0.0 1.2e-19 70.0 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EXF74155.1 - 2.1e-15 57.3 0.0 5.8e-15 55.9 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EXF74155.1 - 1.8e-07 30.5 0.2 6.4e-07 28.7 0.0 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EXF74155.1 - 4e-06 26.5 0.3 0.00048 19.7 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 EXF74155.1 - 0.5 10.3 4.9 0.31 10.9 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3325) UCR_UQCRX_QCR9 PF05365.7 EXF74156.1 - 2.5e-18 65.4 2.2 3.1e-18 65.1 1.5 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Ribonuc_L-PSP PF01042.16 EXF74157.1 - 3.5e-41 139.7 0.0 3.9e-41 139.5 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP PMT PF02366.13 EXF74158.1 - 9.5e-81 270.7 17.4 1.8e-80 269.8 12.1 1.5 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EXF74158.1 - 2.1e-21 76.3 1.1 4.1e-20 72.1 0.2 2.1 1 1 1 2 2 2 2 MIR domain RAMP4 PF06624.7 EXF74158.1 - 0.23 11.0 0.2 0.64 9.5 0.1 1.7 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 DUF334 PF03904.8 EXF74158.1 - 1.2 8.3 2.7 0.55 9.5 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF334) CAP59_mtransfer PF11735.3 EXF74159.1 - 6.9e-82 274.3 0.0 9e-82 273.9 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 zf-C2H2 PF00096.21 EXF74162.1 - 0.016 15.5 2.6 0.016 15.5 1.8 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF74162.1 - 0.51 10.7 18.9 0.086 13.2 1.1 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger Pkinase PF00069.20 EXF74163.1 - 8.6e-13 48.0 0.0 1.5e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF74163.1 - 4e-05 22.8 0.0 7.4e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF74163.1 - 0.0027 16.7 0.0 0.0042 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF3357 PF11837.3 EXF74164.1 - 0.079 12.8 0.5 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) AAA PF00004.24 EXF74165.1 - 1e-07 32.1 1.9 9.2e-07 29.1 0.6 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EXF74165.1 - 0.00015 21.9 0.2 0.0016 18.5 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EXF74165.1 - 0.00047 20.9 0.0 0.0011 19.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EXF74165.1 - 0.0011 19.0 0.1 0.0041 17.1 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 EXF74165.1 - 0.013 14.2 0.0 0.021 13.5 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_18 PF13238.1 EXF74165.1 - 0.023 14.9 0.0 0.079 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EXF74165.1 - 0.03 14.2 0.0 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EXF74165.1 - 0.038 13.7 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain Rad17 PF03215.10 EXF74165.1 - 0.05 12.2 0.0 0.19 10.4 0.0 1.8 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein T2SE PF00437.15 EXF74165.1 - 0.11 11.3 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein 4HB_MCP_1 PF12729.2 EXF74167.1 - 0.043 13.1 0.7 0.12 11.7 0.0 2.0 2 1 0 2 2 2 0 Four helix bundle sensory module for signal transduction DUF3915 PF13054.1 EXF74167.1 - 0.14 12.1 0.2 0.14 12.1 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3915) Strabismus PF06638.6 EXF74167.1 - 0.81 7.9 3.6 1.3 7.2 2.5 1.2 1 0 0 1 1 1 0 Strabismus protein PTCB-BRCT PF12738.2 EXF74168.1 - 7e-44 147.5 0.1 4.5e-19 68.0 0.0 4.4 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.21 EXF74168.1 - 1.5e-37 127.6 0.4 5.4e-11 42.4 0.0 5.0 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain Cullin_binding PF03556.10 EXF74169.1 - 7.9e-33 113.0 6.0 1.3e-32 112.3 4.1 1.4 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.1 EXF74169.1 - 2.6e-10 39.6 0.0 5.1e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Ribosomal_S6 PF01250.12 EXF74170.1 - 6.4e-12 45.1 0.0 7.5e-12 44.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S6 SQS_PSY PF00494.14 EXF74171.1 - 1.2e-51 175.5 0.4 1.5e-51 175.2 0.3 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase SNF2_N PF00176.18 EXF74172.1 - 1.7e-74 250.3 0.1 2.7e-74 249.6 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.6 EXF74172.1 - 2.8e-22 78.6 0.0 7e-22 77.3 0.0 1.7 1 0 0 1 1 1 1 HIRAN domain Helicase_C PF00271.26 EXF74172.1 - 6e-14 51.6 0.0 1.5e-13 50.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EXF74172.1 - 5.6e-07 29.4 9.9 1.1e-06 28.5 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EXF74172.1 - 2.5e-06 27.0 10.9 4.6e-06 26.1 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 EXF74172.1 - 7e-06 25.9 0.0 3.7e-05 23.6 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.1 EXF74172.1 - 1e-05 25.2 10.0 2.4e-05 24.0 6.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EXF74172.1 - 4.3e-05 23.0 8.1 8.2e-05 22.1 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) UBA_4 PF14555.1 EXF74172.1 - 0.001 18.5 0.1 0.0034 16.8 0.1 1.9 1 0 0 1 1 1 1 UBA-like domain PLU-1 PF08429.6 EXF74172.1 - 0.008 15.1 2.6 0.017 14.0 1.8 1.4 1 0 0 1 1 1 1 PLU-1-like protein zf-RING_5 PF14634.1 EXF74172.1 - 0.0086 15.7 8.8 0.019 14.6 6.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Zn-ribbon_8 PF09723.5 EXF74172.1 - 0.55 10.2 4.3 9.3 6.2 0.7 2.6 2 0 0 2 2 2 0 Zinc ribbon domain zf-C3HC4_4 PF15227.1 EXF74172.1 - 3 7.7 8.9 6.3 6.7 6.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EXF74172.1 - 5.8 6.5 9.5 35 4.0 6.7 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain KRTAP PF11759.3 EXF74174.1 - 0.086 13.1 0.2 0.086 13.1 0.1 1.4 2 0 0 2 2 2 0 Keratin-associated matrix SKG6 PF08693.5 EXF74175.1 - 0.0077 15.5 0.7 0.019 14.2 0.5 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Ctr PF04145.10 EXF74175.1 - 0.038 14.0 0.0 0.05 13.6 0.0 1.2 1 0 0 1 1 1 0 Ctr copper transporter family Herpes_gE PF02480.11 EXF74175.1 - 0.057 11.6 0.0 0.091 11.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1183 PF06682.7 EXF74175.1 - 0.065 12.8 0.0 0.08 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Herpes_capsid PF06112.6 EXF74175.1 - 0.31 11.0 3.9 0.47 10.4 2.6 1.4 1 1 0 1 1 1 0 Gammaherpesvirus capsid protein Cucumo_2B PF03263.8 EXF74175.1 - 5.2 7.3 9.6 10 6.4 6.6 1.4 1 0 0 1 1 1 0 Cucumovirus protein 2B DUF755 PF05501.6 EXF74175.1 - 10 6.2 10.8 15 5.6 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) zf-RING_2 PF13639.1 EXF74176.1 - 6.5e-05 22.6 3.8 6.5e-05 22.6 2.6 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EXF74176.1 - 0.0079 16.2 4.1 0.0079 16.2 2.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SnoaL_4 PF13577.1 EXF74177.1 - 1.6e-09 37.7 0.0 2.3e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Glyco_hydro_17 PF00332.13 EXF74178.1 - 1e-07 31.3 0.6 1.6e-07 30.6 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 Sugar_tr PF00083.19 EXF74179.1 - 1.1e-86 291.2 21.0 1.3e-86 290.9 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF74179.1 - 4.4e-25 88.1 43.5 3.1e-19 68.9 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EXF74179.1 - 0.14 11.9 0.1 0.14 11.9 0.1 4.1 4 0 0 4 4 4 0 MFS_1 like family Herpes_LMP1 PF05297.6 EXF74179.1 - 2.9 6.7 5.2 5.6 5.7 3.6 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Glyco_hydro_3 PF00933.16 EXF74180.1 - 1.1e-69 234.7 0.0 1.8e-69 233.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF74180.1 - 9e-63 211.8 0.0 4.4e-62 209.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF74180.1 - 8.9e-14 51.1 0.1 1.9e-13 50.1 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EXF74180.1 - 5.8e-09 35.7 0.0 9.8e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Fungal_trans PF04082.13 EXF74181.1 - 9e-13 47.6 1.3 5.7e-12 45.0 0.9 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF3955 PF13127.1 EXF74181.1 - 0.13 11.7 0.3 0.33 10.5 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3955) Glyco_hydro_28 PF00295.12 EXF74182.1 - 3.1e-94 315.6 23.3 3.8e-94 315.2 16.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EXF74182.1 - 0.00021 21.0 43.9 0.00028 20.6 19.1 3.6 2 2 0 3 3 3 2 Right handed beta helix region ADH_zinc_N PF00107.21 EXF74183.1 - 1.4e-31 108.7 0.1 2.3e-31 108.0 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF74183.1 - 2.4e-16 60.7 0.1 1.6e-15 58.1 0.0 2.1 2 1 1 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF74183.1 - 1.1e-11 44.3 0.0 2.7e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 EXF74183.1 - 0.00046 20.1 0.0 0.00082 19.3 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain AlaDh_PNT_C PF01262.16 EXF74183.1 - 0.033 13.7 0.1 0.057 12.9 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.16 EXF74183.1 - 0.051 13.1 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Terpene_synth_C PF03936.11 EXF74184.1 - 0.0072 15.5 0.0 0.0085 15.3 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.17 EXF74185.1 - 3.7e-48 164.1 0.0 1.1e-45 156.0 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Amdo_NSP PF12475.3 EXF74185.1 - 0.12 12.3 0.2 0.4 10.6 0.0 2.0 2 0 0 2 2 2 0 Amdovirus non-structural protein Asp PF00026.18 EXF74186.1 - 7.4e-56 189.7 0.0 9.2e-56 189.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EXF74186.1 - 1.9e-09 37.6 0.1 1.6e-08 34.6 0.0 2.4 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Serglycin PF04360.7 EXF74186.1 - 0.011 15.5 0.3 0.021 14.5 0.2 1.5 1 0 0 1 1 1 0 Serglycin Asp_protease_2 PF13650.1 EXF74186.1 - 0.042 14.3 0.1 13 6.3 0.0 3.3 2 1 0 2 2 2 0 Aspartyl protease HET PF06985.6 EXF74187.1 - 1.8e-20 73.5 0.0 5.4e-20 71.9 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NACHT PF05729.7 EXF74187.1 - 1.9e-05 24.3 0.0 6.2e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EXF74187.1 - 0.028 14.4 0.0 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EXF74187.1 - 0.041 14.0 0.0 0.84 9.7 0.0 3.1 2 0 0 2 2 2 0 AAA domain SNF2_N PF00176.18 EXF74188.1 - 8.3e-67 225.0 0.1 1.2e-66 224.5 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EXF74188.1 - 1.1e-12 47.6 0.0 2e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EXF74188.1 - 1.2e-07 31.4 0.0 4.4e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-RING_5 PF14634.1 EXF74188.1 - 0.00024 20.7 6.6 0.00051 19.7 4.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain ResIII PF04851.10 EXF74188.1 - 0.001 18.9 0.1 0.012 15.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-RING_2 PF13639.1 EXF74188.1 - 0.0055 16.5 6.5 0.012 15.3 4.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EXF74188.1 - 0.025 14.5 4.1 0.021 14.8 1.4 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EXF74188.1 - 0.088 12.4 5.0 0.22 11.2 3.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF164 PF02591.10 EXF74188.1 - 0.11 12.3 0.6 0.26 11.1 0.4 1.7 1 0 0 1 1 1 0 Putative zinc ribbon domain zf-C3HC4 PF00097.20 EXF74188.1 - 0.14 11.7 6.6 0.35 10.5 4.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.16 EXF74188.1 - 0.28 11.0 3.8 0.72 9.7 2.6 1.6 1 0 0 1 1 1 0 FYVE zinc finger Stc1 PF12898.2 EXF74188.1 - 1.6 8.8 5.5 4.9 7.2 0.4 2.9 2 1 1 3 3 3 0 Stc1 domain Fungal_trans PF04082.13 EXF74190.1 - 6.4e-18 64.5 0.2 1e-17 63.8 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EXF74190.1 - 4.5e-09 36.1 13.6 0.00017 21.7 1.6 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EXF74190.1 - 5.9e-06 26.3 7.4 5.9e-06 26.3 5.2 3.0 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EXF74190.1 - 0.0063 16.7 18.1 0.12 12.8 2.2 3.3 3 0 0 3 3 3 2 C2H2-type zinc finger zf-met PF12874.2 EXF74190.1 - 0.082 13.1 1.3 0.23 11.7 0.9 1.8 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EXF74190.1 - 1.1 9.4 4.4 0.42 10.8 0.4 2.3 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding RINGv PF12906.2 EXF74191.1 - 9.6e-05 22.3 6.7 0.00016 21.6 4.6 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.3 EXF74191.1 - 0.00022 21.0 3.0 0.00042 20.2 2.1 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 EXF74191.1 - 0.00076 19.2 5.3 0.0013 18.5 3.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EXF74191.1 - 0.082 13.0 2.9 0.15 12.1 2.0 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EXF74191.1 - 0.38 10.4 3.4 0.69 9.6 2.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EXF74191.1 - 1.2 8.7 4.5 2.7 7.6 3.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Glyco_hydro_16 PF00722.16 EXF74192.1 - 2.2e-40 137.8 4.5 4.2e-40 136.9 3.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF3112 PF11309.3 EXF74194.1 - 8.9e-39 132.8 5.8 8.9e-39 132.8 4.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3112) Amnionless PF14828.1 EXF74194.1 - 0.018 13.5 0.9 0.075 11.5 0.3 2.1 2 1 1 3 3 3 0 Amnionless MscS_TM PF12794.2 EXF74194.1 - 1.8 7.0 11.7 1.2 7.6 4.6 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Glyco_hydro_39 PF01229.12 EXF74195.1 - 0.034 12.5 0.3 0.075 11.4 0.1 1.5 1 1 1 2 2 2 0 Glycosyl hydrolases family 39 FAD_binding_2 PF00890.19 EXF74196.1 - 5.6e-09 35.3 1.3 8.5e-09 34.7 0.4 1.6 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EXF74196.1 - 7e-09 35.5 0.7 1.3e-08 34.6 0.1 1.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF74196.1 - 6.9e-07 28.4 0.5 5.2e-06 25.5 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EXF74196.1 - 6.2e-06 25.5 0.5 1e-05 24.8 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EXF74196.1 - 9.8e-06 24.2 0.3 1.5e-05 23.6 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EXF74196.1 - 4.9e-05 23.4 0.0 0.00023 21.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF74196.1 - 0.0006 19.7 0.1 0.0012 18.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF74196.1 - 0.00066 18.8 0.1 0.0012 17.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EXF74196.1 - 0.0021 17.0 0.0 0.0033 16.4 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 EXF74196.1 - 0.0031 17.8 0.1 0.0079 16.5 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EXF74196.1 - 0.0089 15.1 0.2 0.014 14.4 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EXF74196.1 - 0.011 14.6 0.2 0.018 13.9 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EXF74196.1 - 0.085 11.4 0.4 0.14 10.7 0.3 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Metallothio PF00131.15 EXF74198.1 - 0.012 15.4 16.5 0.012 15.4 11.4 1.0 1 0 0 1 1 1 0 Metallothionein Metallothio_5 PF02067.10 EXF74198.1 - 0.18 11.8 19.7 0.24 11.4 13.6 1.3 1 1 0 1 1 1 0 Metallothionein family 5 TCR PF03638.10 EXF74198.1 - 4.2 7.2 14.3 13 5.7 9.9 1.8 1 1 0 1 1 1 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain Plant_zn_clust PF10533.4 EXF74198.1 - 7 6.3 10.2 8.2 6.1 7.1 1.3 1 1 0 1 1 1 0 Plant zinc cluster domain PetM PF08041.6 EXF74199.1 - 0.059 12.8 0.5 0.13 11.7 0.3 1.6 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 Prot_inhib_II PF02428.10 EXF74201.1 - 5.6 7.1 10.3 1.6 8.8 4.5 2.1 2 1 0 2 2 2 0 Potato type II proteinase inhibitor family Keratin_B2_2 PF13885.1 EXF74201.1 - 7.7 6.3 12.0 3.9 7.2 1.0 2.8 3 0 0 3 3 3 0 Keratin, high sulfur B2 protein Asp PF00026.18 EXF74203.1 - 8.7e-43 146.7 0.6 2.2e-42 145.4 0.4 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EXF74203.1 - 0.00016 21.2 0.3 0.004 16.7 0.2 2.4 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DUF2235 PF09994.4 EXF74204.1 - 5.5e-54 183.3 0.1 1e-53 182.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Miro PF08477.8 EXF74204.1 - 2.1e-06 28.1 0.0 4.8e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EXF74204.1 - 2e-05 24.5 0.1 4.3e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EXF74204.1 - 4.8e-05 22.6 0.0 9.6e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EXF74204.1 - 0.00096 19.2 0.2 0.039 14.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EXF74204.1 - 0.0015 19.3 0.0 0.0053 17.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 EXF74204.1 - 0.012 14.6 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Septin DUF2200 PF09966.4 EXF74204.1 - 0.043 13.6 0.5 15 5.5 0.1 3.1 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2200) AAA_16 PF13191.1 EXF74204.1 - 0.049 13.6 0.0 0.18 11.7 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EXF74204.1 - 0.11 12.7 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.1 EXF74204.1 - 0.15 12.4 1.4 0.2 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain GalKase_gal_bdg PF10509.4 EXF74205.1 - 3.5e-20 71.0 0.0 6.9e-20 70.0 0.0 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.21 EXF74205.1 - 2.6e-14 53.0 2.0 9.7e-14 51.1 1.0 2.3 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EXF74205.1 - 2.3e-12 46.9 0.0 7.3e-12 45.3 0.0 1.9 1 0 0 1 1 1 1 GHMP kinases C terminal HTH_3 PF01381.17 EXF74205.1 - 0.023 14.5 0.0 0.071 12.9 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix HTH_23 PF13384.1 EXF74205.1 - 0.032 13.8 0.0 0.075 12.7 0.0 1.6 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EXF74205.1 - 0.063 12.7 0.1 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 TRM PF02005.11 EXF74205.1 - 0.14 11.0 0.0 0.22 10.4 0.0 1.4 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase NmrA PF05368.8 EXF74206.1 - 5.1e-34 117.5 0.0 6.7e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF74206.1 - 3.2e-07 30.5 0.1 5.1e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EXF74206.1 - 4.1e-05 22.4 0.0 5.5e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EXF74206.1 - 0.00059 19.3 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EXF74206.1 - 0.00062 19.7 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain adh_short PF00106.20 EXF74206.1 - 0.011 15.6 0.2 0.022 14.6 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Zn_clus PF00172.13 EXF74207.1 - 0.011 15.6 0.6 0.02 14.8 0.4 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF74207.1 - 0.15 10.8 0.9 0.26 10.1 0.1 1.7 2 0 0 2 2 2 0 Fungal specific transcription factor domain FAD_oxidored PF12831.2 EXF74208.1 - 4.9e-52 177.4 0.7 1e-35 123.6 0.0 2.1 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF74208.1 - 7.4e-07 29.1 1.4 2.3e-06 27.5 0.2 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF74208.1 - 1.1e-06 27.8 0.2 1.9e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF74208.1 - 2.3e-06 26.7 1.5 4.8e-06 25.6 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EXF74208.1 - 5.1e-06 25.6 0.2 7.2e-06 25.1 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EXF74208.1 - 2.8e-05 24.4 0.3 6.2e-05 23.3 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF74208.1 - 0.00036 20.4 0.0 0.00057 19.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF74208.1 - 0.022 13.2 0.2 0.032 12.7 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EXF74208.1 - 0.084 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Thi4 family GDI PF00996.13 EXF74208.1 - 0.2 9.9 0.0 0.32 9.2 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Lycopene_cycl PF05834.7 EXF74208.1 - 0.25 10.2 0.8 0.36 9.6 0.6 1.1 1 0 0 1 1 1 0 Lycopene cyclase protein Lactamase_B PF00753.22 EXF74209.1 - 6.3e-06 25.9 0.4 2e-05 24.3 0.2 1.8 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EXF74209.1 - 2.7e-05 23.8 0.0 3.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain p450 PF00067.17 EXF74210.1 - 3.4e-64 217.0 0.0 4.6e-64 216.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EXF74210.1 - 8.2e-23 81.1 2.3 1.4e-22 80.3 1.6 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF74210.1 - 1.1e-14 54.8 0.4 1.8e-14 54.0 0.3 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF74210.1 - 9.1e-11 41.7 0.4 2.1e-10 40.5 0.3 1.6 1 0 0 1 1 1 1 KR domain DUF2800 PF10926.3 EXF74210.1 - 0.039 13.0 0.1 0.064 12.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2800) Epimerase PF01370.16 EXF74210.1 - 0.093 12.1 0.2 0.18 11.1 0.2 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family p450 PF00067.17 EXF74211.1 - 2.4e-64 217.5 0.0 1.2e-52 178.9 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 PS_Dcarbxylase PF02666.10 EXF74212.1 - 3.1e-47 160.4 0.0 4.1e-47 160.1 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase RnfC_N PF13375.1 EXF74212.1 - 0.11 12.2 0.0 9.4 6.0 0.0 2.4 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain NST1 PF13945.1 EXF74213.1 - 4.1e-56 190.0 12.3 4.1e-56 190.0 8.5 5.5 3 2 3 6 6 6 1 Salt tolerance down-regulator Ras PF00071.17 EXF74214.1 - 1.9e-51 173.6 0.0 2.2e-51 173.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EXF74214.1 - 1.7e-15 57.5 0.0 2.5e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EXF74214.1 - 2.4e-06 26.8 0.0 3.7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EXF74214.1 - 0.0053 15.9 0.0 0.0066 15.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EXF74214.1 - 0.04 13.1 0.0 0.053 12.7 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EXF74214.1 - 0.043 13.7 0.0 0.06 13.3 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 EXF74214.1 - 0.046 13.1 0.0 2.6 7.5 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_21 PF13304.1 EXF74214.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain MRP-L28 PF09812.4 EXF74215.1 - 0.00056 19.7 1.0 0.00065 19.5 0.7 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 DUF4202 PF13875.1 EXF74215.1 - 0.018 14.6 0.8 0.022 14.4 0.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4202) DUF3439 PF11921.3 EXF74215.1 - 0.034 13.8 3.2 0.051 13.3 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) AT_hook PF02178.14 EXF74216.1 - 1.7 8.6 7.9 5.7 6.9 5.5 2.0 1 0 0 1 1 1 0 AT hook motif DUF3632 PF12311.3 EXF74217.1 - 3.4e-25 88.9 2.4 8.3e-25 87.6 1.3 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3632) zf-C2H2_4 PF13894.1 EXF74220.1 - 0.15 12.4 11.2 0.24 11.8 0.4 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF74220.1 - 0.15 12.4 11.3 0.48 10.8 1.1 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type NIR_SIR_ferr PF03460.12 EXF74221.1 - 0.04 13.5 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 Nitrite/Sulfite reductase ferredoxin-like half domain zf-C2H2 PF00096.21 EXF74221.1 - 3.5 8.1 7.7 21 5.7 0.2 3.7 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF74221.1 - 8.4 6.9 8.9 8 7.0 0.1 4.2 4 0 0 4 4 4 0 C2H2-type zinc finger TPP_enzyme_N PF02776.13 EXF74222.1 - 1.9e-55 187.0 0.1 1.5e-53 180.7 0.0 2.6 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EXF74222.1 - 1.8e-50 170.5 0.2 1.1e-49 167.9 0.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EXF74222.1 - 2.2e-36 124.6 0.5 6.7e-36 123.0 0.2 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain DUF2500 PF10694.4 EXF74223.1 - 0.063 13.2 0.4 0.17 11.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) Inhibitor_I78 PF11720.3 EXF74224.1 - 2.6e-13 49.4 0.0 3.4e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase inhibitor I78 family potato_inhibit PF00280.13 EXF74224.1 - 3.8e-05 23.7 0.2 5.6e-05 23.1 0.1 1.4 1 1 0 1 1 1 1 Potato inhibitor I family PUA PF01472.15 EXF74225.1 - 3.3e-13 49.1 0.1 1.6e-12 46.9 0.1 1.9 1 1 0 1 1 1 1 PUA domain tRNA-synt_2 PF00152.15 EXF74226.1 - 5.2e-70 235.8 0.0 7.1e-70 235.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EXF74226.1 - 0.0026 17.5 0.1 0.0051 16.6 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Pkinase PF00069.20 EXF74228.1 - 5e-06 25.8 0.0 7.9e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Aldolase_II PF00596.16 EXF74229.1 - 4e-45 153.6 0.0 4.9e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Fungal_trans_2 PF11951.3 EXF74230.1 - 7.3e-48 163.0 0.3 1e-47 162.5 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pectate_lyase PF03211.8 EXF74232.1 - 1.2e-80 269.9 8.9 1.9e-80 269.3 6.2 1.2 1 0 0 1 1 1 1 Pectate lyase Fungal_trans PF04082.13 EXF74233.1 - 2.8e-16 59.1 0.0 4.2e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_3 PF00202.16 EXF74234.1 - 3.3e-91 305.6 0.4 4e-91 305.3 0.2 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EXF74234.1 - 0.016 14.1 0.1 0.036 13.0 0.0 1.5 2 0 0 2 2 2 0 Aminotransferase class I and II MFS_1 PF07690.11 EXF74235.1 - 5.8e-25 87.7 64.6 9.6e-18 63.9 23.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pec_lyase_C PF00544.14 EXF74236.1 - 8.1e-22 77.6 9.0 2.5e-20 72.8 6.2 2.2 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EXF74236.1 - 9.7e-07 28.6 20.3 0.00015 21.5 7.0 2.3 1 1 1 2 2 2 2 Right handed beta helix region Acetyltransf_3 PF13302.1 EXF74237.1 - 8.8e-17 61.5 0.1 1.4e-16 60.9 0.0 1.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EXF74237.1 - 2.5e-07 30.6 0.0 3.9e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EXF74237.1 - 0.00018 21.4 0.0 0.00051 20.0 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EXF74237.1 - 0.034 14.0 0.0 0.048 13.5 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EXF74237.1 - 0.089 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GFO_IDH_MocA PF01408.17 EXF74239.1 - 9.2e-13 48.7 0.1 1.5e-12 48.0 0.0 1.4 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Pterin_bind PF00809.17 EXF74240.1 - 6.6e-61 205.3 0.0 1.1e-60 204.6 0.0 1.4 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.15 EXF74240.1 - 1.9e-40 137.5 0.0 3.2e-40 136.8 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) P12 PF12669.2 EXF74240.1 - 6.9 6.9 9.0 15 5.8 6.2 1.5 1 0 0 1 1 1 0 Virus attachment protein p12 family NMO PF03060.10 EXF74241.1 - 1.6e-71 241.1 1.4 1.8e-71 240.9 0.9 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EXF74241.1 - 3e-08 32.9 0.2 9.7e-08 31.2 0.1 1.8 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EXF74241.1 - 5.4e-06 25.4 2.7 8.8e-06 24.7 1.9 1.3 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EXF74241.1 - 0.0013 17.7 0.7 0.0022 16.9 0.1 1.8 2 0 0 2 2 2 1 Conserved region in glutamate synthase DHO_dh PF01180.16 EXF74241.1 - 0.0042 16.0 0.1 0.0064 15.4 0.1 1.2 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase NanE PF04131.9 EXF74241.1 - 0.056 12.3 0.1 0.13 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase ArfGap PF01412.13 EXF74242.1 - 1.1e-35 121.9 0.1 2.2e-35 120.9 0.1 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf DUF3275 PF11679.3 EXF74242.1 - 0.14 11.7 0.2 0.14 11.7 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3275) TIM21 PF08294.6 EXF74243.1 - 4.2e-43 146.4 0.1 5.2e-43 146.1 0.0 1.1 1 0 0 1 1 1 1 TIM21 Coa1 PF08695.5 EXF74243.1 - 3.6e-06 26.4 0.0 7.1e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Carla_C4 PF01623.12 EXF74243.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein AAA_25 PF13481.1 EXF74246.1 - 2.4e-07 30.3 0.7 1.9e-06 27.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EXF74246.1 - 6.7e-07 28.6 0.0 1.1e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 KaiC RecA PF00154.16 EXF74246.1 - 1e-06 28.0 0.0 1.6e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein DnaB_C PF03796.10 EXF74246.1 - 1e-05 24.5 0.0 0.047 12.5 0.0 2.1 2 0 0 2 2 2 2 DnaB-like helicase C terminal domain AAA_19 PF13245.1 EXF74246.1 - 0.00042 20.0 0.0 0.0013 18.4 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain Rad51 PF08423.6 EXF74246.1 - 0.0056 15.6 0.2 0.21 10.4 0.0 2.2 2 0 0 2 2 2 1 Rad51 AAA_16 PF13191.1 EXF74246.1 - 0.013 15.5 0.3 0.028 14.3 0.2 1.6 1 1 0 1 1 1 0 AAA ATPase domain IstB_IS21 PF01695.12 EXF74246.1 - 0.023 14.1 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.1 EXF74246.1 - 0.029 13.9 0.0 0.037 13.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 EXF74246.1 - 0.047 13.1 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_10 PF12846.2 EXF74246.1 - 0.08 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 EXF74246.1 - 0.14 12.0 0.0 0.24 11.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain zf-H2C2_2 PF13465.1 EXF74247.1 - 2e-10 40.4 18.6 3.5e-06 27.0 2.4 4.0 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_4 PF13894.1 EXF74247.1 - 1.9e-06 27.8 12.0 0.0032 17.7 0.8 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF74247.1 - 3e-06 27.2 19.0 0.0011 19.1 2.9 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type DUF2225 PF09986.4 EXF74247.1 - 0.26 10.7 0.8 0.53 9.7 0.5 1.5 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_6 PF13912.1 EXF74247.1 - 0.63 10.0 3.8 3.2 7.7 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EXF74247.1 - 1.6 8.9 6.5 0.25 11.5 0.4 2.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding adh_short PF00106.20 EXF74248.1 - 7e-32 110.6 0.4 9.4e-32 110.2 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF74248.1 - 9.6e-21 74.6 0.0 1.2e-20 74.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF74248.1 - 2.1e-16 60.0 1.2 4.1e-16 59.1 0.8 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF74248.1 - 0.00016 21.2 0.2 0.00029 20.3 0.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_transf_5 PF08323.6 EXF74248.1 - 0.00075 19.0 0.0 0.022 14.2 0.0 2.4 3 0 0 3 3 3 1 Starch synthase catalytic domain NAD_binding_10 PF13460.1 EXF74248.1 - 0.001 19.1 1.3 0.0052 16.8 0.3 2.4 2 2 0 2 2 2 1 NADH(P)-binding Toprim_3 PF13362.1 EXF74248.1 - 0.013 15.7 0.1 0.28 11.4 0.0 2.3 2 1 0 2 2 2 0 Toprim domain Eno-Rase_NADH_b PF12242.3 EXF74248.1 - 0.026 14.2 0.1 0.052 13.3 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ApbA PF02558.11 EXF74248.1 - 0.066 12.6 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_trans_4_4 PF13579.1 EXF74248.1 - 0.071 13.2 0.1 8.1 6.5 0.0 2.6 3 0 0 3 3 3 0 Glycosyl transferase 4-like domain NmrA PF05368.8 EXF74248.1 - 0.078 12.2 0.2 0.12 11.6 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family THF_DHG_CYH_C PF02882.14 EXF74248.1 - 0.079 12.0 0.0 0.17 10.9 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain MR_MLE_C PF13378.1 EXF74249.1 - 6.6e-32 109.7 0.0 1.8e-31 108.4 0.0 1.7 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 EXF74249.1 - 9.4e-20 70.7 0.0 1.8e-19 69.8 0.0 1.4 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 EXF74249.1 - 5.7e-10 39.5 0.0 1.4e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MFS_1 PF07690.11 EXF74250.1 - 6.7e-52 176.3 38.8 1.8e-50 171.6 27.0 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF74250.1 - 2.9e-11 42.2 16.1 2.9e-11 42.2 11.2 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EXF74250.1 - 2e-09 36.5 11.8 2e-09 36.5 8.2 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter Transp_cyt_pur PF02133.10 EXF74251.1 - 6.8e-80 268.7 38.6 8.7e-80 268.4 26.7 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF4235 PF14019.1 EXF74251.1 - 0.22 11.4 5.1 0.23 11.3 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF4235) Fungal_trans PF04082.13 EXF74252.1 - 1.4e-26 92.9 0.3 1.9e-26 92.4 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Polysacc_deac_1 PF01522.16 EXF74252.1 - 5.7e-09 35.6 0.0 1.5e-08 34.2 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase Zn_clus PF00172.13 EXF74252.1 - 3.9e-05 23.4 3.2 8.6e-05 22.3 2.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 EXF74253.1 - 9.8e-94 314.6 0.0 1.3e-93 314.2 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF690 PF05108.8 EXF74253.1 - 0.019 13.3 0.0 0.029 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF690) MFS_1 PF07690.11 EXF74254.1 - 5.9e-43 146.9 56.8 4.1e-42 144.1 26.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF74254.1 - 1.6e-09 36.9 15.5 1.6e-09 36.9 10.7 3.1 2 2 0 3 3 3 1 Sugar (and other) transporter DUF4174 PF13778.1 EXF74255.1 - 0.015 15.3 0.1 0.029 14.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4174) DUF812 PF05667.6 EXF74255.1 - 0.061 11.8 0.1 0.091 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF932 PF06067.6 EXF74255.1 - 0.15 11.3 0.1 0.29 10.3 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF932) FAD_binding_3 PF01494.14 EXF74256.1 - 5.8e-06 25.6 0.8 0.085 11.8 0.1 3.3 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 EXF74256.1 - 0.00042 19.3 0.1 0.0011 17.9 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF74256.1 - 0.0014 18.6 0.0 0.0036 17.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EXF74256.1 - 0.0017 18.1 0.2 0.0053 16.5 0.1 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EXF74256.1 - 0.012 15.4 0.3 0.027 14.3 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF1013 PF06242.6 EXF74256.1 - 0.014 15.3 0.2 0.061 13.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1013) Pox_A12 PF04651.8 EXF74256.1 - 0.093 12.8 0.2 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A12 protein HI0933_like PF03486.9 EXF74256.1 - 0.12 10.7 0.1 0.22 9.9 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Transferase PF02458.10 EXF74257.1 - 4.4e-43 147.3 0.0 2.7e-18 65.6 0.0 3.0 3 0 0 3 3 3 3 Transferase family DUF1195 PF06708.6 EXF74257.1 - 0.0097 15.3 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1195) Apo-VLDL-II PF05418.6 EXF74257.1 - 0.12 12.5 0.0 0.37 10.9 0.0 1.8 1 0 0 1 1 1 0 Apovitellenin I (Apo-VLDL-II) Tyrosinase PF00264.15 EXF74258.1 - 2.1e-48 165.4 0.1 2.9e-48 164.9 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Viral_Beta_CD PF04530.7 EXF74259.1 - 2.7 8.1 6.1 20 5.3 0.1 3.1 3 0 0 3 3 3 0 Viral Beta C/D like family Gate PF07670.9 EXF74259.1 - 6.7 6.6 10.6 0.6 10.0 2.3 2.7 2 2 1 3 3 3 0 Nucleoside recognition AA_permease_2 PF13520.1 EXF74260.1 - 9.1e-72 241.9 44.4 1.2e-71 241.5 30.8 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF74260.1 - 4.6e-16 58.2 41.7 2.3e-15 55.9 28.9 1.8 1 1 0 1 1 1 1 Amino acid permease Fungal_trans PF04082.13 EXF74261.1 - 0.018 13.9 0.1 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF74261.1 - 0.089 12.7 14.5 0.17 11.8 10.0 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF74262.1 - 3.4e-13 49.0 0.0 5.1e-13 48.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF74262.1 - 6.9e-06 25.8 7.2 1.3e-05 24.9 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ada_Zn_binding PF02805.11 EXF74263.1 - 0.0031 17.0 0.0 0.0069 15.9 0.0 1.6 1 0 0 1 1 1 1 Metal binding domain of Ada PLAC8 PF04749.12 EXF74265.1 - 1.3e-22 80.3 12.3 1.6e-22 80.0 8.5 1.1 1 0 0 1 1 1 1 PLAC8 family p450 PF00067.17 EXF74266.1 - 1.1e-43 149.4 0.0 8.4e-42 143.2 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Epimerase PF01370.16 EXF74267.1 - 2.8e-20 72.7 0.0 4.2e-20 72.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EXF74267.1 - 1.4e-14 53.4 0.0 2e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EXF74267.1 - 1.4e-12 48.0 1.8 2.6e-12 47.1 1.3 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EXF74267.1 - 2.5e-12 46.2 0.0 4.4e-12 45.4 0.0 1.3 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EXF74267.1 - 1.1e-09 38.4 0.5 1.8e-09 37.6 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF74267.1 - 1.8e-07 31.0 0.1 2.7e-07 30.4 0.1 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EXF74267.1 - 2.2e-07 30.0 0.0 3.9e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EXF74267.1 - 0.0027 17.0 0.2 0.0095 15.2 0.1 2.0 2 1 0 2 2 2 1 NmrA-like family F420_oxidored PF03807.12 EXF74267.1 - 0.0029 17.9 0.0 0.011 16.1 0.0 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 EXF74267.1 - 0.0069 15.3 0.1 0.034 13.0 0.1 2.4 1 1 0 1 1 1 1 RmlD substrate binding domain SpoU_sub_bind PF08032.7 EXF74267.1 - 0.14 12.3 0.0 0.71 10.0 0.0 2.1 2 0 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding APC_CDC26 PF10471.4 EXF74268.1 - 0.51 11.1 9.3 0.58 10.9 6.5 1.2 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 Activator_LAG-3 PF11498.3 EXF74268.1 - 0.77 8.4 12.2 0.82 8.3 8.5 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 HeLo PF14479.1 EXF74269.1 - 7.8e-23 81.3 0.0 9.7e-21 74.4 0.0 2.7 2 1 0 2 2 2 1 Prion-inhibition and propagation Pkinase_Tyr PF07714.12 EXF74269.1 - 0.059 12.4 0.0 0.64 9.0 0.0 2.1 2 0 0 2 2 2 0 Protein tyrosine kinase Pkinase PF00069.20 EXF74269.1 - 0.2 10.7 0.0 0.82 8.7 0.0 1.9 1 1 0 1 1 1 0 Protein kinase domain RRM_1 PF00076.17 EXF74270.1 - 4.4e-18 64.6 0.3 8.9e-18 63.7 0.1 1.5 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF74270.1 - 2.5e-13 49.8 0.0 4.1e-13 49.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF74270.1 - 6.4e-09 35.5 0.1 9.7e-09 34.9 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Peptidase_C15 PF01470.12 EXF74272.1 - 1.1e-13 51.5 0.0 7.1e-07 29.2 0.0 2.8 2 1 0 2 2 2 2 Pyroglutamyl peptidase VRR_NUC PF08774.6 EXF74274.1 - 2.4e-17 62.7 0.0 5.4e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain Dpy-30 PF05186.8 EXF74275.1 - 2.1e-11 43.0 0.0 3e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 Dpy-30 motif Ribosomal_S13_N PF08069.7 EXF74276.1 - 3.9e-30 103.4 0.1 7.2e-30 102.6 0.1 1.5 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EXF74276.1 - 2.8e-22 78.2 0.0 4.8e-22 77.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 PAX PF00292.13 EXF74276.1 - 0.018 14.7 0.2 0.044 13.5 0.1 1.7 2 0 0 2 2 2 0 'Paired box' domain RRM_1 PF00076.17 EXF74277.1 - 8.7e-32 108.5 1.8 1.3e-12 47.1 0.0 4.0 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF74277.1 - 1.5e-20 72.9 0.1 3.2e-06 27.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF74277.1 - 3.4e-19 68.4 0.1 8.1e-07 28.8 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_pol3_tau_4 PF12168.3 EXF74277.1 - 0.0043 17.4 0.5 0.012 15.9 0.4 1.7 1 0 0 1 1 1 1 DNA polymerase III subunits tau domain IV DnaB-binding Smg4_UPF3 PF03467.10 EXF74277.1 - 0.035 14.1 0.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Smg-4/UPF3 family Glycophorin_A PF01102.13 EXF74278.1 - 0.44 10.3 0.0 0.44 10.3 0.0 3.6 3 1 1 4 4 4 0 Glycophorin A Fungal_trans PF04082.13 EXF74279.1 - 1e-08 34.4 0.2 7.6e-08 31.5 0.2 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.16 EXF74280.1 - 3.1e-82 275.9 0.0 4.6e-82 275.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF74280.1 - 1.2e-67 227.7 0.0 6.4e-67 225.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF74280.1 - 9.6e-21 73.5 0.1 4.4e-20 71.4 0.0 2.2 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 EXF74280.1 - 1e-08 34.9 0.1 5e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 PA14 domain Sugar_tr PF00083.19 EXF74281.1 - 1.3e-23 83.3 22.4 1.6e-23 83.0 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter HET PF06985.6 EXF74282.1 - 6.9e-21 74.8 6.1 6.8e-18 65.1 0.7 2.7 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) Abhydrolase_6 PF12697.2 EXF74283.1 - 3.5e-18 66.3 1.1 4.6e-18 65.9 0.8 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF74283.1 - 2e-08 34.0 0.2 3e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF74283.1 - 0.0001 21.9 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EXF74283.1 - 0.09 12.3 0.2 0.58 9.7 0.0 2.1 2 1 0 2 2 2 0 Serine hydrolase Methyltransf_23 PF13489.1 EXF74284.1 - 7.3e-22 77.8 0.0 1.2e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF74284.1 - 7.8e-14 51.9 0.0 1.6e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF74284.1 - 2.5e-09 36.8 0.0 3.7e-08 33.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF74284.1 - 2.3e-08 34.4 0.0 9.9e-08 32.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF74284.1 - 4.6e-08 33.6 0.1 1.1e-06 29.2 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF74284.1 - 3.4e-06 26.3 0.0 1.7e-05 24.0 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EXF74284.1 - 3.4e-05 24.1 0.0 0.00012 22.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF74284.1 - 0.001 19.0 0.0 0.0059 16.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF74284.1 - 0.0015 17.6 0.0 0.011 14.7 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_8 PF05148.10 EXF74284.1 - 0.0089 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.9 EXF74284.1 - 0.012 14.9 0.0 0.05 12.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase small domain FtsJ PF01728.14 EXF74284.1 - 0.029 14.3 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 EXF74284.1 - 0.067 12.2 0.0 0.15 11.1 0.0 1.7 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 EXF74284.1 - 0.18 10.8 0.0 0.29 10.1 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Peptidase_S8 PF00082.17 EXF74286.1 - 9.7e-34 116.7 0.0 3e-33 115.1 0.0 1.8 1 1 0 1 1 1 1 Subtilase family PA PF02225.17 EXF74286.1 - 1.6e-13 50.2 0.3 3.5e-13 49.0 0.2 1.6 1 0 0 1 1 1 1 PA domain Inhibitor_I9 PF05922.11 EXF74286.1 - 1.4e-11 44.7 0.0 2.4e-11 44.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Cu-oxidase_3 PF07732.10 EXF74287.1 - 6.9e-47 158.0 6.6 1.2e-45 154.0 0.6 3.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EXF74287.1 - 2.6e-34 117.6 13.5 1.9e-29 101.9 1.0 4.4 4 0 0 4 4 4 3 Multicopper oxidase Cu-oxidase PF00394.17 EXF74287.1 - 4.6e-30 104.6 0.3 1.4e-28 99.7 0.0 2.9 3 1 0 3 3 3 1 Multicopper oxidase Cupredoxin_1 PF13473.1 EXF74287.1 - 0.0047 16.8 0.0 16 5.4 0.0 4.0 3 1 1 4 4 4 2 Cupredoxin-like domain YukC PF10140.4 EXF74287.1 - 0.21 10.1 0.0 0.29 9.6 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Mito_fiss_reg PF05308.6 EXF74287.1 - 1 8.6 7.0 1.8 7.8 4.9 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Beta-lactamase PF00144.19 EXF74288.1 - 1.2e-63 215.1 0.0 1.4e-63 214.8 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Tyrosinase PF00264.15 EXF74289.1 - 2e-48 165.4 0.0 2.7e-48 165.0 0.0 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase FAD_binding_3 PF01494.14 EXF74290.1 - 1.2e-23 83.7 0.0 1.7e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF74290.1 - 3.5e-09 36.0 0.1 5.7e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF74290.1 - 0.00032 20.6 0.0 0.0016 18.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EXF74290.1 - 0.00065 20.0 0.3 0.27 11.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF74290.1 - 0.0038 17.1 0.2 0.016 15.0 0.2 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF74290.1 - 0.0062 15.4 0.1 0.016 14.0 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Trp_halogenase PF04820.9 EXF74290.1 - 0.009 14.6 0.4 1.7 7.2 0.1 2.4 1 1 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.1 EXF74290.1 - 0.045 13.7 0.1 0.18 11.8 0.1 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF74290.1 - 0.1 11.0 0.1 5.8 5.2 0.0 2.8 2 1 1 3 3 3 0 HI0933-like protein Thi4 PF01946.12 EXF74290.1 - 0.1 11.6 0.1 0.2 10.7 0.0 1.5 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 EXF74290.1 - 0.11 11.3 0.4 0.19 10.5 0.3 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A ApbA PF02558.11 EXF74290.1 - 0.12 11.8 0.1 0.22 10.9 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Acetyltransf_3 PF13302.1 EXF74291.1 - 6.5e-16 58.7 0.0 7.6e-15 55.3 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EXF74291.1 - 6.1e-05 22.9 0.1 0.00011 22.1 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EXF74291.1 - 0.097 12.5 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3129 PF11327.3 EXF74292.1 - 3.9e-33 114.8 10.6 3.9e-33 114.8 7.4 3.4 2 2 0 2 2 2 1 Protein of unknown function (DUF3129) HET PF06985.6 EXF74293.1 - 4.5e-16 59.2 1.6 9.7e-16 58.1 1.1 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) APH PF01636.18 EXF74294.1 - 3.2e-41 141.6 0.0 1.1e-40 139.8 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EXF74294.1 - 9.4e-07 28.2 0.0 1.4e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase Fructosamin_kin PF03881.9 EXF74294.1 - 0.0002 20.4 0.0 0.00061 18.8 0.0 1.7 1 1 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.15 EXF74294.1 - 0.00067 19.2 0.0 0.00093 18.8 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EXF74294.1 - 0.0028 16.7 0.0 0.0075 15.3 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EXF74294.1 - 0.0068 15.7 0.0 0.094 12.0 0.0 2.1 2 0 0 2 2 2 1 RIO1 family DUF1679 PF07914.6 EXF74294.1 - 0.022 13.4 0.0 0.094 11.3 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1679) CBFB_NFYA PF02045.10 EXF74295.1 - 7.7e-31 106.4 4.1 1.7e-30 105.3 2.9 1.6 1 0 0 1 1 1 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Hus1 PF04005.7 EXF74295.1 - 0.14 11.0 0.0 0.14 11.0 0.0 1.4 2 0 0 2 2 2 0 Hus1-like protein TFIIA PF03153.8 EXF74295.1 - 0.49 10.2 17.4 0.72 9.6 12.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NAD_binding_8 PF13450.1 EXF74296.1 - 5.9e-10 39.0 0.1 1.2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EXF74296.1 - 1.1e-07 31.2 1.0 2.6e-07 30.0 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EXF74296.1 - 1.1e-07 32.0 0.0 1.9e-06 28.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF74296.1 - 2.1e-07 30.1 3.7 3.5e-07 29.4 2.6 1.3 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF74296.1 - 1e-06 27.9 1.4 1e-06 27.9 1.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EXF74296.1 - 2.1e-06 26.9 0.7 3.7e-06 26.1 0.5 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EXF74296.1 - 2.4e-06 27.5 4.0 2.4e-06 27.5 1.3 2.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF74296.1 - 4.5e-06 25.3 3.3 6.8e-06 24.8 2.3 1.2 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.19 EXF74296.1 - 4.8e-06 25.9 0.0 0.00027 20.1 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase GIDA PF01134.17 EXF74296.1 - 4.1e-05 22.6 0.7 5.9e-05 22.0 0.5 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EXF74296.1 - 4.5e-05 22.6 0.1 7.2e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EXF74296.1 - 0.00018 21.8 0.4 0.00081 19.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EXF74296.1 - 0.0044 17.2 0.1 0.0089 16.2 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EXF74296.1 - 0.0063 15.4 0.1 0.011 14.7 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EXF74296.1 - 0.031 13.8 0.1 0.058 12.9 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 EXF74296.1 - 0.032 12.8 1.5 0.05 12.2 1.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase IlvN PF07991.7 EXF74296.1 - 0.038 13.3 1.1 0.062 12.6 0.1 1.8 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_9 PF13454.1 EXF74296.1 - 0.13 12.0 0.2 0.23 11.2 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding UNC-93 PF05978.11 EXF74297.1 - 0.013 15.0 5.0 0.013 15.0 3.5 2.2 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 TM_helix PF05552.7 EXF74297.1 - 2.7 7.7 9.4 8.5 6.1 1.2 3.1 3 0 0 3 3 3 0 Conserved TM helix Tyrosinase PF00264.15 EXF74298.1 - 6.7e-47 160.5 0.8 9.1e-47 160.0 0.5 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase adh_short PF00106.20 EXF74300.1 - 1.1e-21 77.4 1.9 2.5e-21 76.3 1.3 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF74300.1 - 2e-09 37.4 0.1 2.6e-09 36.9 0.1 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF74300.1 - 1.7e-08 34.5 0.0 2.4e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EXF74300.1 - 1e-05 25.6 0.4 2.6e-05 24.2 0.3 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF74300.1 - 0.00053 19.4 0.0 0.00061 19.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EXF74300.1 - 0.063 12.4 0.0 0.14 11.2 0.0 1.5 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) SET PF00856.23 EXF74301.1 - 7.1e-13 49.1 0.0 2.4e-12 47.4 0.0 1.9 1 1 0 1 1 1 1 SET domain Metallophos_2 PF12850.2 EXF74302.1 - 2.3e-08 34.0 0.0 6.8e-08 32.5 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EXF74302.1 - 1.2e-07 31.3 0.1 2e-07 30.6 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF1907 PF08925.6 EXF74304.1 - 1.8e-104 348.8 0.0 2e-104 348.6 0.0 1.0 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1907) F-box-like PF12937.2 EXF74305.1 - 0.003 17.2 0.6 0.003 17.2 0.4 2.2 2 0 0 2 2 2 1 F-box-like Mad3_BUB1_I PF08311.7 EXF74306.1 - 2.1e-42 143.8 0.2 5.6e-42 142.5 0.1 1.7 2 0 0 2 2 2 1 Mad3/BUB1 homology region 1 Pkinase PF00069.20 EXF74306.1 - 6.1e-11 41.9 0.0 1.6e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Mad3_BUB1_II PF08171.6 EXF74306.1 - 0.012 15.4 0.0 0.061 13.2 0.0 2.2 1 1 0 1 1 1 0 Mad3/BUB1 homology region 2 PI3K_1B_p101 PF10486.4 EXF74306.1 - 0.02 12.5 10.7 0.0049 14.5 4.8 1.8 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pkinase_Tyr PF07714.12 EXF74306.1 - 0.026 13.6 0.0 0.12 11.4 0.0 2.0 1 1 0 1 1 1 0 Protein tyrosine kinase AP_endonuc_2 PF01261.19 EXF74307.1 - 3.8e-33 114.5 0.5 5.6e-33 114.0 0.4 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DAGAT PF03982.8 EXF74308.1 - 8.5e-94 313.5 0.0 1.2e-93 313.1 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase WLM PF08325.5 EXF74309.1 - 8.8e-49 165.9 0.2 8.8e-49 165.9 0.1 2.5 3 0 0 3 3 3 1 WLM domain DUF4110 PF13422.1 EXF74309.1 - 6.1e-27 93.2 0.6 6.1e-27 93.2 0.4 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF4110) Kelch_3 PF13415.1 EXF74309.1 - 8.5e-25 86.2 12.3 6.3e-08 32.5 0.0 6.3 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EXF74309.1 - 1.3e-18 66.5 1.9 9e-08 31.9 0.0 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 EXF74309.1 - 2.7e-18 65.4 11.3 3.8e-05 23.3 0.0 6.1 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_2 PF07646.10 EXF74309.1 - 4.4e-14 51.6 0.6 0.0031 17.2 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 EXF74309.1 - 1.1e-10 41.2 1.6 0.00035 20.6 0.1 4.4 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.20 EXF74309.1 - 2.2e-10 39.9 0.2 3e-05 23.4 0.0 4.5 4 0 0 4 4 4 1 Kelch motif DUF45 PF01863.12 EXF74309.1 - 2.1e-07 30.9 0.1 2.1e-07 30.9 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function DUF45 CHGN PF05679.11 EXF74309.1 - 0.1 11.3 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Chondroitin N-acetylgalactosaminyltransferase DUF1664 PF07889.7 EXF74312.1 - 0.069 12.9 0.1 0.092 12.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Thioredoxin PF00085.15 EXF74313.1 - 7.5e-64 211.9 9.4 1e-31 108.6 0.1 4.1 4 1 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.1 EXF74313.1 - 5.6e-53 179.4 1.9 3.9e-39 134.3 0.2 3.7 2 2 2 4 4 4 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EXF74313.1 - 8.8e-13 48.1 0.1 6.6e-05 22.9 0.0 4.0 2 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EXF74313.1 - 3.8e-12 46.0 1.4 2.7e-05 24.1 0.0 3.2 4 0 0 4 4 3 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EXF74313.1 - 5.6e-11 42.6 5.2 9.3e-05 22.6 0.1 4.3 2 2 1 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.16 EXF74313.1 - 1.6e-08 34.2 1.9 0.0025 17.4 0.1 3.2 3 0 0 3 3 3 2 AhpC/TSA family Calsequestrin PF01216.12 EXF74313.1 - 3.7e-08 32.5 0.8 3.7e-08 32.5 0.5 2.4 1 1 1 3 3 3 1 Calsequestrin Redoxin PF08534.5 EXF74313.1 - 1.6e-07 31.0 3.5 0.00046 19.7 0.0 3.4 3 1 0 3 3 3 2 Redoxin Thioredoxin_3 PF13192.1 EXF74313.1 - 0.0037 17.0 0.1 0.025 14.3 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_4 PF13462.1 EXF74313.1 - 0.011 15.6 8.3 4.4 7.3 1.5 4.2 3 1 0 3 3 3 0 Thioredoxin DSBA PF01323.15 EXF74313.1 - 0.023 14.2 0.3 10 5.5 0.0 4.0 3 1 0 3 3 3 0 DSBA-like thioredoxin domain NMD3 PF04981.8 EXF74313.1 - 0.35 9.9 2.6 3.6 6.6 0.0 2.9 3 0 0 3 3 3 0 NMD3 family CDC45 PF02724.9 EXF74315.1 - 0.1 10.5 3.8 0.15 10.0 2.6 1.2 1 0 0 1 1 1 0 CDC45-like protein eIF3g PF12353.3 EXF74315.1 - 1.9 8.4 16.5 8.3 6.3 5.8 3.1 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G DDHD PF02862.12 EXF74315.1 - 3.8 7.2 9.5 0.98 9.1 4.3 1.7 2 1 0 2 2 2 0 DDHD domain Mon1 PF03164.9 EXF74316.1 - 8.1e-114 380.4 0.0 9.7e-114 380.1 0.0 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Dopey_N PF04118.9 EXF74317.1 - 8.2e-117 389.3 0.0 2.8e-116 387.6 0.0 1.9 2 0 0 2 2 2 1 Dopey, N-terminal Duffy_binding PF05424.6 EXF74317.1 - 0.43 10.3 0.0 0.78 9.5 0.0 1.3 1 0 0 1 1 1 0 Duffy binding domain Methyltransf_15 PF09445.5 EXF74318.1 - 3.6e-46 156.7 0.0 4.9e-46 156.2 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EXF74318.1 - 1.4e-07 31.5 0.0 2.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EXF74318.1 - 9.2e-06 25.3 0.0 1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 EXF74318.1 - 1.7e-05 25.3 0.0 2.4e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EXF74318.1 - 0.00013 21.6 0.0 0.00027 20.5 0.0 1.5 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Cons_hypoth95 PF03602.10 EXF74318.1 - 0.0012 18.2 0.0 0.0021 17.5 0.0 1.4 1 1 0 1 1 1 1 Conserved hypothetical protein 95 MTS PF05175.9 EXF74318.1 - 0.15 11.4 0.0 0.24 10.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain GRASP55_65 PF04495.9 EXF74319.1 - 5.3e-46 156.0 0.0 1.8e-45 154.3 0.0 1.7 2 0 0 2 2 2 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EXF74319.1 - 0.17 11.8 0.0 0.38 10.6 0.0 1.6 2 0 0 2 2 2 0 PDZ domain DAD PF02109.11 EXF74320.1 - 1.7e-41 140.8 0.2 2.1e-41 140.5 0.2 1.1 1 0 0 1 1 1 1 DAD family NifW PF03206.9 EXF74320.1 - 0.075 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Nitrogen fixation protein NifW Tmemb_14 PF03647.8 EXF74321.1 - 3.5e-24 85.0 6.4 3.9e-24 84.8 4.4 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF2416 PF10315.4 EXF74321.1 - 0.061 13.5 0.1 0.17 12.1 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2416) Cmc1 PF08583.5 EXF74322.1 - 2.1e-15 56.2 3.4 2.5e-15 55.9 2.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like bZIP_1 PF00170.16 EXF74322.1 - 2.5 8.1 10.9 3.8 7.5 7.5 1.2 1 0 0 1 1 1 0 bZIP transcription factor Prefoldin_2 PF01920.15 EXF74323.1 - 2.1e-23 82.0 10.9 2.6e-23 81.7 7.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit DUF2205 PF10224.4 EXF74323.1 - 0.0092 15.5 9.0 0.045 13.3 0.7 2.1 2 0 0 2 2 2 2 Predicted coiled-coil protein (DUF2205) IIGP PF05049.8 EXF74323.1 - 0.012 14.4 1.0 0.014 14.2 0.7 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) TACC PF05010.9 EXF74323.1 - 0.02 14.6 5.0 0.025 14.3 3.5 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) TMP_2 PF06791.8 EXF74323.1 - 0.056 13.0 0.8 0.065 12.8 0.5 1.1 1 0 0 1 1 1 0 Prophage tail length tape measure protein CDC37_N PF03234.9 EXF74323.1 - 0.06 13.6 6.3 0.078 13.3 4.3 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Syntaxin-6_N PF09177.6 EXF74323.1 - 0.073 13.4 3.6 2.2 8.7 0.4 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal RUN PF02759.14 EXF74323.1 - 0.089 12.5 0.2 0.11 12.2 0.1 1.2 1 0 0 1 1 1 0 RUN domain Tho2 PF11262.3 EXF74323.1 - 0.13 11.2 2.9 1.8 7.5 0.1 2.0 1 1 1 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Mnd1 PF03962.10 EXF74323.1 - 0.16 11.6 7.3 0.33 10.5 5.1 1.6 1 1 0 1 1 1 0 Mnd1 family STAT_alpha PF01017.15 EXF74323.1 - 0.16 11.6 9.7 0.22 11.1 6.7 1.2 1 0 0 1 1 1 0 STAT protein, all-alpha domain Trigger_C PF05698.9 EXF74323.1 - 0.24 11.2 7.2 0.3 10.9 5.0 1.3 1 0 0 1 1 1 0 Bacterial trigger factor protein (TF) C-terminus MIF4G_like_2 PF09090.6 EXF74323.1 - 0.26 10.5 2.7 0.29 10.3 1.9 1.1 1 0 0 1 1 1 0 MIF4G like DUF641 PF04859.7 EXF74323.1 - 0.33 10.6 4.8 0.22 11.2 1.2 1.8 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) IncA PF04156.9 EXF74323.1 - 0.41 10.2 7.2 0.62 9.6 5.0 1.3 1 1 0 1 1 1 0 IncA protein DUF4337 PF14235.1 EXF74323.1 - 0.55 10.0 5.0 1.2 8.9 0.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) Sec8_exocyst PF04048.9 EXF74323.1 - 0.56 9.8 5.2 0.8 9.3 0.4 2.0 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain V_ATPase_I PF01496.14 EXF74323.1 - 0.84 7.4 4.7 0.62 7.8 2.1 1.5 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF148 PF02520.12 EXF74323.1 - 1.1 9.0 8.6 2.6 7.8 3.9 2.1 1 1 1 2 2 2 0 Domain of unknown function DUF148 YkuI_C PF10388.4 EXF74323.1 - 1.2 8.7 5.0 3.1 7.4 0.4 2.0 1 1 0 2 2 2 0 EAL-domain associated signalling protein domain Prefoldin PF02996.12 EXF74323.1 - 1.7 8.3 10.3 3.4 7.3 1.0 2.4 1 1 2 3 3 3 0 Prefoldin subunit DUF3166 PF11365.3 EXF74323.1 - 1.7 9.1 5.6 11 6.5 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3166) FliJ PF02050.11 EXF74323.1 - 1.7 8.6 11.0 2.1 8.4 0.6 2.2 2 0 0 2 2 2 0 Flagellar FliJ protein Cytochrom_B562 PF07361.6 EXF74323.1 - 1.9 8.9 6.3 3.9 7.9 0.9 2.1 2 0 0 2 2 2 0 Cytochrome b562 DASH_Dad3 PF08656.5 EXF74323.1 - 2.8 7.6 6.6 0.81 9.4 1.0 2.0 2 0 0 2 2 2 0 DASH complex subunit Dad3 TMF_DNA_bd PF12329.3 EXF74323.1 - 5.7 6.8 9.2 3.6 7.4 1.0 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CBFD_NFYB_HMF PF00808.18 EXF74324.1 - 3.3e-22 78.3 0.8 1.7e-14 53.6 0.2 2.3 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EXF74324.1 - 0.0003 20.8 0.1 0.023 14.8 0.1 2.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 RRN3 PF05327.6 EXF74325.1 - 5.4e-164 546.4 0.4 8.7e-164 545.7 0.0 1.4 1 1 1 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 DUF2372 PF10178.4 EXF74325.1 - 0.13 12.4 0.0 0.43 10.7 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2372) SPT2 PF08243.6 EXF74326.1 - 0.017 15.4 0.8 0.017 15.4 0.5 2.0 2 0 0 2 2 2 0 SPT2 chromatin protein Rad60-SLD_2 PF13881.1 EXF74327.1 - 3.4e-12 46.2 0.0 6.9e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EXF74327.1 - 7.9e-06 25.1 0.0 1.5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EXF74327.1 - 0.0025 17.9 0.1 0.0072 16.4 0.0 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain UMP1 PF05348.6 EXF74328.1 - 2.6e-25 88.8 0.0 3.1e-25 88.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 ABC_tran PF00005.22 EXF74329.1 - 1.6e-22 80.3 0.0 9.7e-10 38.8 0.0 3.6 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EXF74329.1 - 3.3e-09 37.1 0.0 0.074 13.0 0.0 4.1 3 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EXF74329.1 - 6.1e-07 29.2 1.5 0.00092 19.0 0.1 3.0 3 0 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EXF74329.1 - 6.3e-06 27.0 0.0 0.1 13.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EXF74329.1 - 7.7e-05 22.8 0.1 0.62 10.2 0.0 3.0 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.1 EXF74329.1 - 0.0001 21.7 0.1 0.19 11.2 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EXF74329.1 - 0.00048 20.5 0.3 0.37 11.0 0.1 2.2 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EXF74329.1 - 0.0026 17.7 0.0 1.9 8.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EXF74329.1 - 0.0066 15.8 0.1 2.7 7.3 0.0 3.1 4 0 0 4 4 4 1 AAA domain Miro PF08477.8 EXF74329.1 - 0.0093 16.4 0.0 1 9.8 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein AAA_14 PF13173.1 EXF74329.1 - 0.0098 15.7 0.0 1.5 8.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EXF74329.1 - 0.013 15.3 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EXF74329.1 - 0.016 14.9 0.0 6 6.5 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EXF74329.1 - 0.021 14.2 0.5 6.7 6.0 0.0 2.6 3 1 0 3 3 2 0 AAA-like domain AAA_28 PF13521.1 EXF74329.1 - 0.056 13.4 0.0 13 5.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EXF74329.1 - 0.059 13.6 0.1 9.8 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EXF74329.1 - 0.061 12.8 0.0 0.49 9.8 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EXF74329.1 - 0.074 12.7 0.0 5.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase RNA_helicase PF00910.17 EXF74329.1 - 0.078 13.1 0.0 1.9 8.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 EXF74329.1 - 0.08 13.1 0.1 1.2 9.3 0.0 2.8 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EXF74329.1 - 0.15 11.5 0.0 10 5.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family SMC_N PF02463.14 EXF74329.1 - 0.17 11.0 0.1 3.2 6.8 0.0 2.4 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_24 PF13479.1 EXF74329.1 - 0.19 11.2 0.0 6.1 6.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EXF74329.1 - 0.21 10.7 0.0 10 5.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF258 SRPRB PF09439.5 EXF74329.1 - 0.29 10.3 0.0 8.5 5.5 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 EXF74329.1 - 0.32 10.5 0.1 2.8 7.3 0.0 2.0 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_13 PF13166.1 EXF74329.1 - 0.35 9.2 0.0 0.8 8.0 0.0 1.5 2 0 0 2 2 2 0 AAA domain Chitin_synth_1 PF01644.12 EXF74330.1 - 3.8e-83 277.1 0.1 6.6e-83 276.4 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EXF74330.1 - 1.2e-32 111.4 0.1 3e-32 110.1 0.1 1.7 1 0 0 1 1 1 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EXF74330.1 - 7e-22 77.4 2.1 3e-19 68.8 0.0 2.3 2 0 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EXF74330.1 - 1.7e-10 40.9 0.2 1.7e-10 40.9 0.2 2.3 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EXF74330.1 - 1.2e-06 28.5 0.0 2.9e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 DUF1361 PF07099.6 EXF74330.1 - 0.0014 18.4 2.1 0.0014 18.4 1.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1361) DUF4551 PF15087.1 EXF74330.1 - 0.096 11.0 5.9 0.15 10.4 4.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Tyrosinase PF00264.15 EXF74331.1 - 9.1e-36 124.0 0.1 3.6e-35 122.1 0.1 2.0 1 1 0 1 1 1 1 Common central domain of tyrosinase Tannase PF07519.6 EXF74332.1 - 1.3e-144 482.4 8.5 1.6e-144 482.1 5.9 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase MFS_1 PF07690.11 EXF74333.1 - 1e-08 34.3 7.1 1.4e-07 30.5 6.0 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF2512 PF10710.4 EXF74333.1 - 0.0099 15.3 0.7 4.4 6.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2512) Asparaginase_2 PF01112.13 EXF74334.1 - 4.5e-85 285.1 3.5 5.6e-85 284.8 2.5 1.0 1 0 0 1 1 1 1 Asparaginase Aminotran_3 PF00202.16 EXF74335.1 - 3.3e-49 167.5 0.0 4.6e-48 163.8 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-III MFS_1 PF07690.11 EXF74336.1 - 1.4e-44 152.2 31.3 1.4e-44 152.2 21.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF74336.1 - 1.4e-12 46.9 9.2 1.4e-12 46.9 6.4 2.4 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EXF74336.1 - 8.1e-06 24.3 6.5 1.4e-05 23.5 4.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EXF74336.1 - 3.3e-05 22.4 5.2 3.3e-05 22.4 3.6 3.1 2 2 2 4 4 4 2 MFS/sugar transport protein MFS_3 PF05977.8 EXF74336.1 - 0.00057 18.1 8.8 0.00057 18.1 6.1 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector DUF3735 PF12537.3 EXF74337.1 - 0.021 14.8 1.4 0.037 14.0 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3735) Herpes_gE PF02480.11 EXF74337.1 - 0.075 11.2 1.4 0.078 11.2 0.0 1.6 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E DUF1191 PF06697.7 EXF74337.1 - 0.084 11.6 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) SnoaL_3 PF13474.1 EXF74339.1 - 9e-07 28.9 0.1 1.2e-06 28.5 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 EXF74339.1 - 2.7e-05 24.4 0.0 3.8e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 EXF74339.1 - 6.9e-05 22.7 0.1 0.00016 21.5 0.1 1.6 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EXF74339.1 - 0.00026 21.1 0.1 0.00035 20.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.7 EXF74339.1 - 0.034 13.7 0.0 0.044 13.3 0.0 1.2 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase NTF2 PF02136.15 EXF74339.1 - 0.14 12.5 0.0 0.2 12.0 0.0 1.3 1 1 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain peroxidase PF00141.18 EXF74340.1 - 7.2e-87 290.6 0.1 2.2e-47 161.4 0.0 2.4 2 0 0 2 2 2 2 Peroxidase Amidohydro_4 PF13147.1 EXF74341.1 - 5.8e-20 72.4 1.2 1.1e-19 71.5 0.8 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EXF74341.1 - 7.7e-07 28.8 1.7 2.8e-06 27.0 0.6 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 EXF74341.1 - 9.5e-07 28.7 1.1 3.1e-06 27.0 0.8 1.9 1 1 0 1 1 1 1 Amidohydrolase family PAF-AH_p_II PF03403.8 EXF74342.1 - 8.5e-19 67.0 0.1 6.7e-15 54.2 0.1 2.1 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EXF74342.1 - 2.1e-12 46.9 0.1 3.2e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EXF74342.1 - 0.00037 19.4 0.0 0.00085 18.2 0.0 1.6 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_6 PF12697.2 EXF74342.1 - 0.0012 18.7 0.8 0.0035 17.2 0.5 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EXF74342.1 - 0.012 15.2 0.0 0.016 14.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Lipase_3 PF01764.20 EXF74342.1 - 0.074 12.6 0.1 0.2 11.2 0.1 1.6 1 1 0 1 1 1 0 Lipase (class 3) Chlorophyllase PF07224.6 EXF74342.1 - 0.092 11.5 0.0 1.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase Peptidase_S9 PF00326.16 EXF74342.1 - 0.11 11.7 0.2 0.22 10.7 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family Acetyltransf_7 PF13508.1 EXF74343.1 - 1e-05 25.5 0.0 1.4e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EXF74343.1 - 2.5e-05 24.1 0.1 3.8e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EXF74343.1 - 0.0007 19.7 0.7 0.00091 19.3 0.5 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EXF74343.1 - 0.0015 18.4 0.9 0.0055 16.5 0.6 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EXF74343.1 - 0.002 18.0 0.0 0.0027 17.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EXF74343.1 - 0.017 15.0 0.0 0.027 14.3 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Cutinase PF01083.17 EXF74344.1 - 1.4e-26 93.2 1.0 1.4e-26 93.2 0.7 1.7 2 0 0 2 2 2 1 Cutinase Sporozoite_P67 PF05642.6 EXF74344.1 - 0.072 10.9 8.3 0.087 10.6 5.7 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TraG-D_C PF12696.2 EXF74344.1 - 0.2 11.5 2.4 0.37 10.6 1.7 1.4 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG Kelch_3 PF13415.1 EXF74344.1 - 0.26 11.5 1.9 1.5 9.0 1.4 2.4 1 1 0 1 1 1 0 Galactose oxidase, central domain Pex14_N PF04695.8 EXF74344.1 - 0.95 9.5 6.8 1.7 8.6 4.7 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MSA-2c PF12238.3 EXF74344.1 - 8.7 5.9 8.9 16 5.0 6.2 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c Peptidase_M28 PF04389.12 EXF74345.1 - 5.6e-35 120.6 0.0 8.6e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EXF74345.1 - 1e-09 37.9 0.5 2.6e-09 36.6 0.3 1.7 1 0 0 1 1 1 1 PA domain Ribosomal_L36e PF01158.13 EXF74347.1 - 0.0057 16.5 1.2 0.021 14.7 0.8 1.9 1 0 0 1 1 1 1 Ribosomal protein L36e PBP1_TM PF14812.1 EXF74347.1 - 4 7.8 13.8 10 6.5 1.0 3.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DEAD PF00270.24 EXF74348.1 - 8.6e-42 142.4 0.1 1.3e-41 141.8 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF74348.1 - 2.2e-17 62.6 0.0 5.2e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EXF74348.1 - 1.3e-15 56.6 0.1 2.6e-15 55.7 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.10 EXF74348.1 - 0.018 14.8 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit IBR PF01485.16 EXF74349.1 - 7.3e-15 54.5 35.6 5.7e-09 35.7 3.9 3.6 3 1 0 3 3 3 2 IBR domain zf-C3HC4 PF00097.20 EXF74349.1 - 0.00063 19.3 0.1 0.00063 19.3 0.1 3.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EXF74349.1 - 0.0025 17.8 0.9 0.0025 17.8 0.6 4.2 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EXF74349.1 - 0.0052 16.5 0.7 0.0052 16.5 0.5 3.9 2 1 2 4 4 4 1 Ring finger domain zf-RING_5 PF14634.1 EXF74349.1 - 0.033 13.8 0.8 0.033 13.8 0.6 3.9 3 1 0 3 3 3 0 zinc-RING finger domain HHA PF05321.6 EXF74349.1 - 0.87 9.7 2.8 0.7 10.0 0.1 2.1 2 0 0 2 2 2 0 Haemolysin expression modulating protein GHMP_kinases_N PF00288.21 EXF74350.1 - 2.6e-15 56.2 2.4 8.5e-15 54.5 1.5 2.0 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EXF74350.1 - 1.7e-07 31.2 0.3 3.8e-07 30.2 0.2 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal DUF4075 PF13294.1 EXF74350.1 - 0.13 12.2 0.0 0.43 10.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4075) PPR_2 PF13041.1 EXF74351.1 - 7.6e-47 157.0 7.1 2.2e-09 37.1 0.0 14.7 9 3 7 16 16 16 10 PPR repeat family PPR PF01535.15 EXF74351.1 - 2.7e-24 83.4 31.3 0.00032 20.4 0.0 14.7 18 0 0 18 18 18 6 PPR repeat PPR_3 PF13812.1 EXF74351.1 - 9.6e-23 78.5 34.5 0.00033 20.7 0.0 17.1 20 0 0 20 20 20 5 Pentatricopeptide repeat domain PPR_1 PF12854.2 EXF74351.1 - 4.8e-20 70.7 0.0 1.8e-08 33.7 0.0 9.7 11 0 0 11 11 11 3 PPR repeat RPM2 PF08579.6 EXF74351.1 - 6.6e-06 26.2 0.0 0.00094 19.3 0.0 4.0 4 0 0 4 4 4 1 Mitochondrial ribonuclease P subunit (RPM2) ATP13 PF12921.2 EXF74351.1 - 0.001 18.4 0.7 0.36 10.2 0.1 4.2 3 1 1 4 4 4 1 Mitochondrial ATPase expression SelB-wing_1 PF09105.5 EXF74351.1 - 0.076 12.6 0.2 6.1 6.5 0.0 2.9 2 0 0 2 2 2 0 Elongation factor SelB, winged helix MIF4G PF02854.14 EXF74353.1 - 2.4e-61 206.8 0.0 3.5e-30 104.9 0.0 3.4 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.9 EXF74353.1 - 2.9e-58 196.4 14.7 2.9e-58 196.4 10.2 2.4 3 0 0 3 3 3 1 Up-frameshift suppressor 2 CBP4 PF07960.6 EXF74353.1 - 0.035 13.7 0.0 0.035 13.7 0.0 3.0 4 0 0 4 4 4 0 CBP4 Mo-co_dimer PF03404.11 EXF74354.1 - 5.7e-56 187.7 0.0 1.2e-55 186.7 0.0 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Oxidored_molyb PF00174.14 EXF74354.1 - 5.6e-50 169.0 0.0 9.1e-50 168.3 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain FAD_binding_6 PF00970.19 EXF74354.1 - 1.9e-30 104.9 0.0 4.2e-30 103.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 EXF74354.1 - 2.4e-20 72.0 0.0 5.4e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.16 EXF74354.1 - 3.1e-20 72.7 0.0 6.9e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EXF74354.1 - 0.01 15.7 0.0 0.071 13.0 0.0 2.1 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Na_Ca_ex PF01699.19 EXF74355.1 - 2.2e-27 95.3 18.3 2.1e-15 56.5 1.2 2.4 2 1 0 2 2 2 2 Sodium/calcium exchanger protein DUF4536 PF15055.1 EXF74355.1 - 0.0004 20.3 0.5 0.0019 18.2 0.3 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) 7tm_7 PF08395.7 EXF74355.1 - 0.0015 17.6 2.1 0.015 14.3 0.0 2.7 1 1 2 3 3 3 1 7tm Chemosensory receptor N_methyl_2 PF13544.1 EXF74355.1 - 1.1 8.8 0.0 1.1 8.8 0.0 3.2 3 0 0 3 3 3 0 Type IV pilin N-term methylation site GFxxxE DEAD PF00270.24 EXF74357.1 - 7.8e-28 97.0 0.0 8.3e-27 93.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF1998 PF09369.5 EXF74357.1 - 2.7e-12 47.0 0.2 8.3e-12 45.5 0.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Helicase_C PF00271.26 EXF74357.1 - 1.5e-09 37.5 0.0 5.1e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CDT1 PF08839.6 EXF74357.1 - 0.0058 16.5 0.2 0.025 14.4 0.0 2.1 2 0 0 2 2 2 1 DNA replication factor CDT1 like Ran_BP1 PF00638.13 EXF74358.1 - 1.4e-11 44.5 0.1 0.00017 21.6 0.0 2.5 2 0 0 2 2 2 2 RanBP1 domain MIP-T3 PF10243.4 EXF74358.1 - 6.9 5.0 28.1 0.056 11.9 8.5 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Yip1 PF04893.12 EXF74359.1 - 3.3e-13 49.5 13.3 4.8e-13 48.9 9.2 1.4 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.7 EXF74359.1 - 0.91 9.1 11.8 1.8 8.2 8.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) PAS_3 PF08447.6 EXF74360.1 - 3.9e-15 55.7 0.0 8.5e-12 45.0 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 EXF74360.1 - 1.4e-11 44.6 0.0 9.2e-06 25.9 0.0 2.8 3 0 0 3 3 3 2 PAS domain PAS_11 PF14598.1 EXF74360.1 - 2.5e-07 30.6 0.0 1.2e-06 28.4 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EXF74360.1 - 4.3e-07 29.6 0.0 0.00048 19.8 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 EXF74360.1 - 0.00046 20.2 0.0 0.06 13.3 0.0 2.6 2 0 0 2 2 2 1 PAS fold YL1 PF05764.8 EXF74360.1 - 0.81 9.2 3.8 1.3 8.6 2.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein WD40 PF00400.27 EXF74361.1 - 8.5e-14 50.8 22.8 1.2e-05 25.0 0.7 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat RNA_pol_I_TF PF04090.7 EXF74362.1 - 6.5e-05 22.2 0.0 0.038 13.2 0.0 2.2 2 0 0 2 2 2 2 RNA polymerase I specific initiation factor BAR_2 PF10455.4 EXF74363.1 - 3.5e-58 196.8 0.0 5.4e-58 196.1 0.0 1.3 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EXF74363.1 - 3.5e-20 72.4 0.3 2.9e-19 69.4 0.2 2.1 1 1 0 1 1 1 1 BAR domain ETC_C1_NDUFA5 PF04716.9 EXF74363.1 - 7.8e-20 70.1 0.6 2.3e-19 68.6 0.4 1.9 1 0 0 1 1 1 1 ETC complex I subunit conserved region DUF619 PF04768.8 EXF74364.1 - 8.5e-51 171.7 0.0 3.2e-50 169.8 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF619) NAD_binding_2 PF03446.10 EXF74365.1 - 1.2e-27 96.7 0.2 1.7e-27 96.2 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EXF74365.1 - 5.8e-12 45.7 0.4 4.2e-10 39.7 0.0 2.2 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EXF74365.1 - 3e-09 37.1 0.0 8.1e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EXF74365.1 - 3.8e-09 36.7 0.1 6.6e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EXF74365.1 - 0.00036 19.7 0.0 0.00057 19.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_3 PF03447.11 EXF74365.1 - 0.00041 20.7 0.2 0.00095 19.5 0.1 1.7 1 1 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain TrkA_N PF02254.13 EXF74365.1 - 0.00051 20.0 0.1 0.0012 18.8 0.0 1.7 2 0 0 2 2 1 1 TrkA-N domain Semialdhyde_dh PF01118.19 EXF74365.1 - 0.0069 16.6 0.0 0.018 15.3 0.0 1.7 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EXF74365.1 - 0.0094 14.9 0.2 0.027 13.4 0.1 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase HTH_Tnp_Mu_2 PF09039.6 EXF74365.1 - 0.013 15.1 0.0 0.075 12.7 0.0 2.0 2 0 0 2 2 2 0 Mu DNA binding, I gamma subdomain GFO_IDH_MocA PF01408.17 EXF74365.1 - 0.014 15.9 0.0 0.029 14.8 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold OCD_Mu_crystall PF02423.10 EXF74365.1 - 0.014 14.2 0.2 0.018 13.8 0.2 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family UDPG_MGDP_dh_N PF03721.9 EXF74365.1 - 0.015 14.6 0.2 0.059 12.7 0.1 2.0 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EXF74365.1 - 0.032 13.9 0.3 0.092 12.4 0.2 1.8 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ATP_synt_H PF05493.8 EXF74366.1 - 8.8e-27 92.9 1.1 9.9e-27 92.8 0.8 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF4131 PF13567.1 EXF74366.1 - 0.01 15.2 1.5 0.01 15.2 1.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) 7TMR-DISM_7TM PF07695.6 EXF74366.1 - 0.022 14.4 0.2 0.025 14.2 0.1 1.0 1 0 0 1 1 1 0 7TM diverse intracellular signalling ARL6IP6 PF15062.1 EXF74366.1 - 0.03 14.2 0.1 0.039 13.8 0.1 1.3 1 1 0 1 1 1 0 Haemopoietic lineage transmembrane helix 5TM-5TMR_LYT PF07694.7 EXF74366.1 - 0.17 11.2 1.8 0.18 11.1 1.2 1.0 1 0 0 1 1 1 0 5TMR of 5TMR-LYT Arv1 PF04161.8 EXF74367.1 - 2.6e-47 161.4 0.2 3.4e-47 161.0 0.1 1.1 1 0 0 1 1 1 1 Arv1-like family LysM PF01476.15 EXF74368.1 - 0.026 14.4 0.0 0.044 13.6 0.0 1.4 1 0 0 1 1 1 0 LysM domain Fungal_trans PF04082.13 EXF74369.1 - 4.3e-38 130.6 0.1 3e-37 127.8 0.0 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF74369.1 - 8.6e-08 31.9 8.3 1.5e-07 31.2 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GHMP_kinases_N PF00288.21 EXF74369.1 - 0.65 10.1 3.3 1.6 8.8 2.3 1.6 1 0 0 1 1 1 0 GHMP kinases N terminal domain PigN PF04987.9 EXF74370.1 - 7e-160 532.4 31.1 7e-160 532.4 21.6 1.5 2 0 0 2 2 2 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EXF74370.1 - 6.1e-09 35.6 2.2 1.8e-07 30.7 1.3 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EXF74370.1 - 4.1e-08 32.7 0.1 6.4e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EXF74370.1 - 0.00043 19.7 0.0 0.0007 19.0 0.0 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Csm1 PF12539.3 EXF74371.1 - 2.3e-26 92.0 0.0 4.6e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Csm1/Pcs1 Spc7 PF08317.6 EXF74371.1 - 0.0041 15.8 6.2 0.0084 14.8 4.3 1.4 1 0 0 1 1 1 1 Spc7 kinetochore protein ADIP PF11559.3 EXF74371.1 - 0.016 15.0 6.5 0.037 13.9 4.5 1.6 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Macoilin PF09726.4 EXF74371.1 - 0.033 12.4 22.8 0.043 12.0 15.8 1.1 1 0 0 1 1 1 0 Transmembrane protein Atg14 PF10186.4 EXF74371.1 - 0.035 13.0 5.7 0.065 12.1 3.9 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2968 PF11180.3 EXF74371.1 - 0.088 12.1 8.8 0.25 10.7 6.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) TBPIP PF07106.8 EXF74371.1 - 0.12 11.9 4.9 0.075 12.5 1.5 2.0 2 0 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Sulfatase_C PF14707.1 EXF74371.1 - 0.13 12.5 0.5 0.29 11.4 0.3 1.5 1 0 0 1 1 1 0 C-terminal region of aryl-sulfatase TMCO5 PF14992.1 EXF74371.1 - 0.13 11.3 4.7 0.3 10.2 3.2 1.5 1 0 0 1 1 1 0 TMCO5 family GAS PF13851.1 EXF74371.1 - 0.14 11.3 8.8 0.14 11.3 3.3 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding PilO PF04350.8 EXF74371.1 - 0.38 10.6 4.0 0.61 9.9 2.3 1.7 1 1 0 1 1 1 0 Pilus assembly protein, PilO DUF3571 PF12095.3 EXF74371.1 - 0.52 10.5 2.5 1.4 9.1 1.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3571) Fib_alpha PF08702.5 EXF74371.1 - 0.69 10.0 3.9 3.3 7.8 2.5 2.2 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family FemAB PF02388.11 EXF74371.1 - 0.86 8.2 9.2 0.027 13.1 2.0 1.6 2 0 0 2 2 2 0 FemAB family IncA PF04156.9 EXF74371.1 - 4.9 6.6 14.3 1.7 8.1 7.4 2.0 2 1 0 2 2 2 0 IncA protein AAA PF00004.24 EXF74372.1 - 3e-38 130.9 0.0 5.4e-38 130.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EXF74372.1 - 3.8e-06 27.0 0.0 2.3e-05 24.4 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EXF74372.1 - 7e-06 26.2 0.5 0.00086 19.4 0.0 2.8 2 1 1 3 3 2 1 AAA domain RuvB_N PF05496.7 EXF74372.1 - 7.7e-06 25.1 0.0 2e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EXF74372.1 - 8.9e-06 25.6 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EXF74372.1 - 3.2e-05 23.6 0.1 0.00023 20.8 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EXF74372.1 - 4.9e-05 23.3 0.0 8.3e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.1 EXF74372.1 - 0.00011 23.0 0.0 0.00026 21.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EXF74372.1 - 0.0013 18.6 0.0 0.0032 17.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EXF74372.1 - 0.0013 17.8 0.0 0.0026 16.8 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Sigma54_activ_2 PF14532.1 EXF74372.1 - 0.0014 18.7 0.0 0.0048 16.9 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EXF74372.1 - 0.0016 17.6 0.1 0.0033 16.6 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EXF74372.1 - 0.0016 17.8 0.0 0.0029 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 EXF74372.1 - 0.0021 17.4 0.8 0.1 11.9 0.1 2.6 2 1 1 3 3 2 1 AAA domain AAA_19 PF13245.1 EXF74372.1 - 0.0026 17.4 0.2 0.0091 15.7 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 EXF74372.1 - 0.0035 17.4 0.0 0.011 15.9 0.0 1.9 2 0 0 2 2 1 1 RNA helicase DUF815 PF05673.8 EXF74372.1 - 0.0055 15.6 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) NACHT PF05729.7 EXF74372.1 - 0.0061 16.2 0.0 0.016 14.8 0.0 1.7 2 0 0 2 2 1 1 NACHT domain Sigma54_activat PF00158.21 EXF74372.1 - 0.012 15.0 0.0 0.031 13.7 0.0 1.6 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 EXF74372.1 - 0.013 15.4 0.1 0.035 14.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain TOMM6 PF15184.1 EXF74372.1 - 0.017 14.4 0.2 0.038 13.3 0.1 1.5 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog NB-ARC PF00931.17 EXF74372.1 - 0.018 13.9 0.0 0.052 12.3 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_24 PF13479.1 EXF74372.1 - 0.02 14.4 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EXF74372.1 - 0.029 14.0 0.0 0.16 11.6 0.0 2.0 1 1 1 2 2 2 0 Archaeal ATPase AAA_18 PF13238.1 EXF74372.1 - 0.035 14.4 0.0 0.1 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Guanylate_kin PF00625.16 EXF74372.1 - 0.042 13.2 0.1 0.21 11.0 0.0 2.2 2 1 0 2 2 2 0 Guanylate kinase Oxidored_nitro PF00148.14 EXF74372.1 - 0.048 12.3 0.0 0.2 10.2 0.0 1.9 2 0 0 2 2 2 0 Nitrogenase component 1 type Oxidoreductase TIP49 PF06068.8 EXF74372.1 - 0.055 12.1 0.0 0.096 11.3 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus Bac_DnaA PF00308.13 EXF74372.1 - 0.064 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein ABC_tran PF00005.22 EXF74372.1 - 0.089 13.0 0.0 0.18 12.0 0.0 1.7 1 1 0 1 1 1 0 ABC transporter Parvo_NS1 PF01057.12 EXF74372.1 - 0.1 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_10 PF12846.2 EXF74372.1 - 0.15 11.4 0.3 2.9 7.2 0.0 2.8 3 1 0 3 3 3 0 AAA-like domain Rad17 PF03215.10 EXF74372.1 - 0.16 10.6 0.0 0.24 10.0 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein zf-C2H2_4 PF13894.1 EXF74373.1 - 3.1e-06 27.1 12.7 0.00057 20.0 1.3 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EXF74373.1 - 6.3e-06 26.2 4.0 6.3e-06 26.2 2.8 3.0 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2 PF00096.21 EXF74373.1 - 1.4e-05 25.1 11.4 0.0064 16.7 0.9 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type Nucleo_P87 PF07267.6 EXF74373.1 - 0.22 10.1 4.6 0.45 9.1 3.2 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CobT PF06213.7 EXF74373.1 - 0.68 9.0 5.1 1 8.4 3.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PBP1_TM PF14812.1 EXF74373.1 - 2 8.7 7.4 4.6 7.6 5.1 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal zf-C2H2_6 PF13912.1 EXF74373.1 - 2.3 8.2 5.8 0.35 10.8 0.6 2.3 2 0 0 2 2 2 0 C2H2-type zinc finger Tannase PF07519.6 EXF74374.1 - 1.2e-49 169.3 0.0 6.4e-31 107.5 0.0 2.4 2 1 1 3 3 3 2 Tannase and feruloyl esterase Glyco_hydro_47 PF01532.15 EXF74375.1 - 1.3e-167 558.0 0.0 1.5e-167 557.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 COesterase PF00135.23 EXF74376.1 - 6.2e-63 213.3 7.3 1.6e-62 211.9 5.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF74376.1 - 0.00054 19.5 1.1 0.0038 16.8 0.2 2.6 2 1 0 2 2 2 1 alpha/beta hydrolase fold Ank_2 PF12796.2 EXF74377.1 - 2.9e-09 37.1 0.0 5.2e-09 36.3 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EXF74377.1 - 1.4e-08 34.1 0.1 8.3e-05 22.1 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EXF74377.1 - 3.9e-06 26.9 0.4 0.00041 20.4 0.1 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EXF74377.1 - 1.5e-05 25.3 0.0 0.0018 18.7 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF74377.1 - 0.00036 20.4 0.0 0.17 12.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Candida_ALS PF05792.8 EXF74379.1 - 0.008 16.2 11.1 0.008 16.2 7.7 16.0 15 3 1 16 16 16 6 Candida agglutinin-like (ALS) DUF1065 PF06358.6 EXF74380.1 - 0.11 12.2 0.1 0.15 11.8 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1065) Glyco_hydro_75 PF07335.6 EXF74381.1 - 1.2e-48 164.9 0.1 1.6e-48 164.5 0.1 1.2 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 Sugar_tr PF00083.19 EXF74383.1 - 2.8e-94 316.2 30.8 3.2e-94 316.0 21.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF74383.1 - 1.4e-25 89.8 57.8 7.9e-23 80.7 20.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M35 PF02102.10 EXF74384.1 - 1.6e-28 99.4 16.1 2.3e-28 98.8 11.1 1.2 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EXF74384.1 - 5.5e-08 33.4 0.3 1.2e-07 32.3 0.2 1.6 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 EXF74384.1 - 0.00013 21.5 2.0 0.00013 21.5 1.4 1.8 2 0 0 2 2 2 1 Putative peptidase family CARDB PF07705.6 EXF74384.1 - 0.047 13.7 2.7 0.051 13.6 0.1 2.3 2 1 0 2 2 2 0 CARDB Inhibitor_I67 PF11405.3 EXF74384.1 - 6.3 6.9 7.0 0.64 10.1 1.4 1.9 2 0 0 2 2 2 0 Bromelain inhibitor VI Sel1 PF08238.7 EXF74385.1 - 1.5e-13 50.8 8.4 0.0021 18.6 0.1 4.4 4 0 0 4 4 4 3 Sel1 repeat Proteasome PF00227.21 EXF74386.1 - 7.7e-47 159.0 0.1 9.5e-47 158.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EXF74386.1 - 1.5e-11 43.3 0.2 3.5e-11 42.1 0.1 1.7 1 0 0 1 1 1 1 Proteasome beta subunits C terminal WD40 PF00400.27 EXF74387.1 - 0.0093 15.8 0.0 0.096 12.6 0.0 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat Ribosomal_L35Ae PF01247.13 EXF74388.1 - 1.6e-41 139.9 0.8 1.8e-41 139.8 0.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae RimM PF01782.13 EXF74388.1 - 1.2e-05 25.0 0.1 0.0084 16.0 0.0 2.2 2 0 0 2 2 2 2 RimM N-terminal domain G6PD_C PF02781.11 EXF74389.1 - 1.1e-133 444.5 0.0 1.7e-133 444.0 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EXF74389.1 - 8.4e-64 215.1 0.0 1.4e-63 214.4 0.0 1.4 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Med14 PF08638.6 EXF74390.1 - 1.9e-67 226.3 0.0 3.6e-67 225.4 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit MED14 Amino_oxidase PF01593.19 EXF74391.1 - 2.1e-15 56.7 0.0 7.2e-08 31.9 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EXF74391.1 - 2.1e-12 46.8 0.0 6.3e-12 45.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF74391.1 - 1.1e-08 34.4 0.1 4.3e-07 29.1 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EXF74391.1 - 2.3e-06 27.7 0.2 0.0021 18.1 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF74391.1 - 8.8e-06 26.0 1.4 0.025 14.9 0.1 3.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF74391.1 - 6.2e-05 22.8 0.0 0.012 15.3 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EXF74391.1 - 0.00012 22.0 0.0 0.012 15.4 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EXF74391.1 - 0.0038 15.9 0.1 0.0058 15.3 0.1 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.12 EXF74391.1 - 0.004 16.2 0.0 0.0071 15.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family BAR_2 PF10455.4 EXF74391.1 - 0.028 13.3 0.0 0.044 12.6 0.0 1.2 1 0 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking FAD_binding_2 PF00890.19 EXF74391.1 - 0.048 12.5 1.2 0.062 12.1 0.1 1.8 2 0 0 2 2 2 0 FAD binding domain zf-CCCH_2 PF14608.1 EXF74392.1 - 5.8e-14 51.4 57.1 2.3e-07 30.5 7.3 5.4 5 0 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type Nab2 PF11517.3 EXF74392.1 - 0.014 15.4 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Glyco_hydro_20 PF00728.17 EXF74393.1 - 3.8e-85 286.1 0.0 5.3e-85 285.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EXF74393.1 - 1.4e-25 90.3 0.1 2.5e-25 89.5 0.1 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EXF74393.1 - 9.8e-09 35.8 0.1 1.7e-07 31.7 0.1 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 p450 PF00067.17 EXF74394.1 - 3.4e-60 203.8 0.0 5.6e-60 203.1 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_1_2 PF00155.16 EXF74395.1 - 1.2e-16 60.7 0.0 1.5e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EXF74395.1 - 1.1e-05 24.2 0.0 4.2e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 EXF74395.1 - 0.0015 17.6 0.1 0.047 12.7 0.0 2.1 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Glyco_hydro_16 PF00722.16 EXF74396.1 - 1.5e-43 148.2 1.8 2.2e-43 147.6 1.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 FYVE PF01363.16 EXF74397.1 - 5.9e-21 74.1 0.6 5.9e-21 74.1 0.4 2.9 3 0 0 3 3 3 1 FYVE zinc finger zf-RING_2 PF13639.1 EXF74397.1 - 6.3e-08 32.3 6.0 6.3e-08 32.3 4.2 3.6 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 EXF74397.1 - 0.0092 16.0 4.1 0.0092 16.0 2.8 3.4 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EXF74397.1 - 0.018 14.7 3.6 0.018 14.7 2.5 3.5 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EXF74397.1 - 0.021 14.8 6.0 0.021 14.8 4.1 3.7 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 EXF74397.1 - 0.034 13.5 0.4 0.034 13.5 0.3 2.0 2 0 0 2 2 2 0 Rad50 zinc hook motif Elf1 PF05129.8 EXF74397.1 - 0.77 9.4 11.0 0.2 11.3 2.1 2.8 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like FYVE_2 PF02318.11 EXF74397.1 - 1.4 8.7 9.3 1.1 9.2 1.9 2.4 2 0 0 2 2 2 0 FYVE-type zinc finger zf-piccolo PF05715.8 EXF74397.1 - 2.7 8.0 8.8 7.3 6.6 2.9 2.8 2 0 0 2 2 2 0 Piccolo Zn-finger p450 PF00067.17 EXF74398.1 - 4e-29 101.4 0.0 5.1e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Thioesterase PF00975.15 EXF74399.1 - 1.1e-12 48.7 0.0 3.3e-05 24.2 0.0 3.0 2 1 0 2 2 2 2 Thioesterase domain Abhydrolase_6 PF12697.2 EXF74399.1 - 0.00021 21.2 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF74399.1 - 0.0015 18.3 0.0 0.0019 17.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EXF74399.1 - 0.037 13.6 0.0 0.055 13.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EXF74399.1 - 0.042 13.2 0.0 0.076 12.4 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase MFS_1 PF07690.11 EXF74401.1 - 1.9e-17 63.0 47.4 5.1e-10 38.5 18.5 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF74401.1 - 5.5e-11 41.3 14.0 1e-10 40.4 9.7 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) CorA PF01544.13 EXF74402.1 - 1.6e-05 24.0 1.0 1.6e-05 24.0 0.7 3.1 3 1 0 3 3 3 1 CorA-like Mg2+ transporter protein ADH_zinc_N PF00107.21 EXF74403.1 - 7.3e-16 57.9 0.1 1.5e-15 56.8 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF74403.1 - 2.6e-15 57.4 0.2 1.3e-14 55.1 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF74403.1 - 3e-08 33.3 0.0 2.2e-07 30.5 0.0 2.3 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain Propeptide_C1 PF08127.8 EXF74403.1 - 0.47 10.1 2.0 0.38 10.4 0.1 1.8 2 0 0 2 2 2 0 Peptidase family C1 propeptide Fungal_trans PF04082.13 EXF74404.1 - 8.1e-11 41.2 0.1 1.7e-10 40.2 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain ATP-synt_D PF01813.12 EXF74404.1 - 0.011 15.2 0.0 0.022 14.3 0.0 1.4 1 0 0 1 1 1 0 ATP synthase subunit D Apc5 PF12862.2 EXF74404.1 - 0.11 12.2 1.2 4.5 7.1 0.2 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 HET PF06985.6 EXF74405.1 - 6.1e-23 81.5 0.3 1.1e-22 80.7 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) fn3 PF00041.16 EXF74406.1 - 1.1e-15 57.5 4.9 2.1e-05 24.5 0.0 3.3 3 0 0 3 3 3 3 Fibronectin type III domain Lipase_GDSL_2 PF13472.1 EXF74406.1 - 4.9e-09 36.5 0.0 2.3e-08 34.3 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EXF74406.1 - 0.0011 18.8 0.0 0.0063 16.3 0.0 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ChitinaseA_N PF08329.5 EXF74406.1 - 0.036 13.8 0.5 0.16 11.7 0.1 2.2 2 0 0 2 2 2 0 Chitinase A, N-terminal domain DUF3328 PF11807.3 EXF74408.1 - 5.6e-47 160.2 0.8 7.4e-47 159.8 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2235 PF09994.4 EXF74409.1 - 1.1e-71 241.4 7.7 8.4e-44 150.0 0.4 3.2 2 1 0 3 3 3 3 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF3415 PF11895.3 EXF74410.1 - 0.017 14.9 0.2 0.028 14.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3415) Clr5 PF14420.1 EXF74411.1 - 8.7e-18 63.9 0.5 8.7e-18 63.9 0.4 1.8 2 0 0 2 2 2 1 Clr5 domain Podoplanin PF05808.6 EXF74411.1 - 1.1 8.7 4.4 0.54 9.8 0.8 1.9 2 0 0 2 2 2 0 Podoplanin Fungal_trans PF04082.13 EXF74412.1 - 3.1e-11 42.6 3.2 6e-11 41.7 2.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF74412.1 - 1.2e-10 41.1 10.4 1.9e-10 40.4 7.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAT1 PF09770.4 EXF74412.1 - 0.073 11.3 27.2 0.13 10.4 18.8 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribonuclease_T2 PF00445.13 EXF74414.1 - 1.5e-28 99.6 0.0 2.3e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family Bac_luciferase PF00296.15 EXF74414.1 - 0.1 11.7 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Luciferase-like monooxygenase WSC PF01822.14 EXF74415.1 - 8.8e-06 25.5 0.4 1.5e-05 24.8 0.3 1.4 1 0 0 1 1 1 1 WSC domain Peptidase_C2 PF00648.16 EXF74416.1 - 3.1e-12 46.1 0.0 5.5e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Calpain family cysteine protease Peptidase_C1 PF00112.18 EXF74416.1 - 0.072 12.9 0.2 0.12 12.2 0.2 1.3 1 0 0 1 1 1 0 Papain family cysteine protease MFS_1 PF07690.11 EXF74417.1 - 1.2e-22 80.0 39.4 1.2e-22 80.0 27.3 1.6 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.8 EXF74417.1 - 0.012 13.7 0.6 0.012 13.7 0.4 1.9 2 0 0 2 2 2 0 Transmembrane secretion effector Methyltransf_23 PF13489.1 EXF74418.1 - 9.4e-22 77.4 0.0 1.9e-21 76.4 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF74418.1 - 4.5e-11 42.5 0.0 6.7e-10 38.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF74418.1 - 1.5e-10 41.6 0.0 1.7e-09 38.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF74418.1 - 2.5e-09 37.5 0.0 6.2e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF74418.1 - 5.3e-08 33.2 0.0 7e-07 29.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF74418.1 - 0.0019 17.3 0.0 0.06 12.4 0.0 2.3 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EXF74418.1 - 0.0036 17.6 0.0 0.0084 16.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF74418.1 - 0.0087 15.1 0.0 0.019 14.0 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.13 EXF74418.1 - 0.012 14.8 0.0 0.06 12.5 0.0 1.8 2 0 0 2 2 2 0 O-methyltransferase FtsJ PF01728.14 EXF74418.1 - 0.015 15.3 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 EXF74418.1 - 0.017 14.2 0.0 0.033 13.3 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EXF74418.1 - 0.021 14.1 0.0 0.047 13.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain CheR PF01739.13 EXF74418.1 - 0.072 12.3 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_26 PF13659.1 EXF74418.1 - 0.085 12.8 0.0 0.23 11.5 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain GPI-anchored PF10342.4 EXF74419.1 - 2.5e-17 63.1 3.3 2.5e-17 63.1 2.3 2.4 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Methyltransf_31 PF13847.1 EXF74424.1 - 2e-16 59.9 0.0 2.7e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF74424.1 - 3.7e-16 59.3 0.0 9.1e-16 58.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF74424.1 - 8e-15 54.5 0.0 2.8e-14 52.7 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EXF74424.1 - 3.5e-10 40.1 0.0 8.7e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF74424.1 - 4.8e-10 39.8 0.0 7.5e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF74424.1 - 3.4e-08 33.3 0.0 5.5e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF74424.1 - 4.3e-08 33.7 0.0 6.6e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF74424.1 - 3.2e-07 30.3 0.0 7.5e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF74424.1 - 0.00022 20.6 0.0 0.00041 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.10 EXF74424.1 - 0.0028 17.3 0.0 0.012 15.2 0.0 1.8 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_32 PF13679.1 EXF74424.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EXF74424.1 - 0.044 13.1 0.0 0.19 11.1 0.0 1.9 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW DASH_Ask1 PF08655.5 EXF74424.1 - 0.085 12.6 0.1 3.2 7.6 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Ask1 RPN7 PF10602.4 EXF74426.1 - 1e-45 155.2 0.0 2.1e-45 154.2 0.0 1.5 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 EXF74426.1 - 6.3e-14 52.1 0.0 1.4e-13 51.0 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_2 PF07719.12 EXF74426.1 - 0.071 13.0 0.0 2.8 8.0 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Zn_clus PF00172.13 EXF74428.1 - 5.3e-07 29.4 7.5 7.7e-07 28.9 5.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Peptidase_M20 PF01546.23 EXF74429.1 - 5.1e-22 78.2 0.0 1.2e-21 77.0 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.27 EXF74429.1 - 2.8e-18 65.0 0.0 0.003 17.3 0.0 5.9 5 0 0 5 5 5 4 WD domain, G-beta repeat M20_dimer PF07687.9 EXF74429.1 - 0.005 16.5 0.0 0.0088 15.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Nucleoporin_N PF08801.6 EXF74429.1 - 0.0075 15.0 0.0 1.7 7.2 0.0 2.9 2 1 1 3 3 3 2 Nup133 N terminal like Invas_SpaK PF03519.9 EXF74429.1 - 0.023 14.5 0.1 0.48 10.3 0.0 2.7 3 0 0 3 3 3 0 Invasion protein B family DUF4285 PF14113.1 EXF74430.1 - 0.027 14.4 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4285) Nuc_deoxyrib_tr PF05014.10 EXF74430.1 - 0.057 13.2 0.0 0.072 12.9 0.0 1.3 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase TFIIA PF03153.8 EXF74431.1 - 0.0074 16.2 18.7 0.011 15.6 13.0 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit CAF-1_p150 PF11600.3 EXF74431.1 - 0.7 9.2 25.2 0.46 9.8 13.6 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal LUC7 PF03194.10 EXF74432.1 - 3.7e-69 233.0 3.1 4.6e-69 232.7 2.2 1.0 1 0 0 1 1 1 1 LUC7 N_terminus GRP PF07172.6 EXF74432.1 - 0.052 14.0 7.4 0.13 12.7 5.2 1.7 1 0 0 1 1 1 0 Glycine rich protein family DUF3450 PF11932.3 EXF74432.1 - 0.082 12.1 0.4 0.15 11.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) zf-C4H2 PF10146.4 EXF74432.1 - 0.1 12.6 0.5 0.16 11.9 0.4 1.3 1 0 0 1 1 1 0 Zinc finger-containing protein DUF3418 PF11898.3 EXF74432.1 - 0.18 10.1 1.6 0.32 9.3 0.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF3418) Occludin_ELL PF07303.8 EXF74432.1 - 1.6 9.5 6.2 0.56 10.9 0.5 2.5 2 1 1 3 3 3 0 Occludin homology domain Gpi16 PF04113.9 EXF74433.1 - 9.3e-237 786.5 0.0 1.2e-236 786.1 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Peptidase_S8 PF00082.17 EXF74434.1 - 3.2e-47 161.0 1.2 4.3e-47 160.5 0.8 1.2 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EXF74434.1 - 9.1e-07 29.2 0.0 1.7e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 EXF74434.1 - 0.0013 18.3 0.0 0.0034 17.0 0.0 1.6 1 0 0 1 1 1 1 PA domain MFS_1 PF07690.11 EXF74435.1 - 1.2e-19 70.2 40.4 1.2e-19 70.2 28.0 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF74435.1 - 0.0022 16.6 14.9 0.0022 16.6 10.3 3.2 2 2 1 3 3 3 1 Sugar (and other) transporter DUF3533 PF12051.3 EXF74436.1 - 7.1e-64 215.9 14.6 8.4e-64 215.6 10.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) Pectinesterase PF01095.14 EXF74437.1 - 6.7e-53 179.1 8.6 8.3e-53 178.8 6.0 1.1 1 0 0 1 1 1 1 Pectinesterase DUF3762 PF12591.3 EXF74437.1 - 0.13 12.3 1.3 0.23 11.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3762) DUF1295 PF06966.7 EXF74438.1 - 0.1 11.8 0.4 0.14 11.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Glyco_hydro_61 PF03443.9 EXF74440.1 - 1.4e-79 266.9 0.3 1.4e-79 266.9 0.2 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 MFS_1 PF07690.11 EXF74441.1 - 2.8e-34 118.3 45.3 6.2e-30 104.0 18.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.10 EXF74441.1 - 5.2e-05 22.1 10.8 0.03 13.0 0.6 3.2 2 1 0 3 3 3 3 PUCC protein Aldolase_II PF00596.16 EXF74441.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain Zn_clus PF00172.13 EXF74442.1 - 2.1e-08 33.9 11.6 2.1e-08 33.9 8.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF74443.1 - 2.6e-18 65.8 0.2 4.2e-18 65.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF74443.1 - 0.00095 19.0 7.2 0.0019 18.0 5.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EXF74444.1 - 8.3e-81 271.8 10.0 9.6e-81 271.6 6.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF74444.1 - 1.5e-16 60.1 11.2 1.5e-16 60.1 7.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EXF74444.1 - 0.023 12.8 4.0 0.013 13.7 0.8 1.8 2 0 0 2 2 2 0 Fungal trichothecene efflux pump (TRI12) DUF1228 PF06779.9 EXF74444.1 - 0.051 13.5 0.4 0.051 13.5 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) Fungal_trans PF04082.13 EXF74445.1 - 4.5e-13 48.6 0.3 9e-13 47.6 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF74445.1 - 5.8e-13 48.5 20.7 2.5e-08 33.6 8.1 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Seryl_tRNA_N PF02403.17 EXF74445.1 - 0.025 14.5 0.3 9.9 6.2 0.3 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Cu_amine_oxid PF01179.15 EXF74446.1 - 8.1e-118 393.7 8.3 9.9e-118 393.4 5.7 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 EXF74446.1 - 4.6e-33 112.9 0.7 1.6e-32 111.2 0.5 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) Cu_amine_oxidN2 PF02727.11 EXF74446.1 - 5.3e-06 26.4 0.0 1.5e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Pheromone PF08015.6 EXF74447.1 - 0.031 15.0 2.0 0.072 13.9 1.4 1.7 1 0 0 1 1 1 0 Fungal mating-type pheromone DUF3278 PF11683.3 EXF74447.1 - 1.2 9.1 5.5 4.6 7.2 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3278) GMC_oxred_N PF00732.14 EXF74448.1 - 2.2e-24 86.1 0.0 4.8e-24 85.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF74448.1 - 6.2e-23 81.6 0.1 1.2e-22 80.8 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EXF74448.1 - 1.1e-09 37.6 0.7 0.00017 20.5 0.0 2.4 3 0 0 3 3 3 2 FAD binding domain CBM_1 PF00734.13 EXF74448.1 - 1.5e-08 34.1 7.9 5.9e-08 32.2 5.5 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain DAO PF01266.19 EXF74448.1 - 1.2e-06 27.6 0.1 0.00012 21.1 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF74448.1 - 6.4e-05 22.9 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF74448.1 - 0.00012 22.0 0.0 0.00041 20.3 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EXF74448.1 - 0.00066 19.7 0.0 0.016 15.2 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF74448.1 - 0.00091 17.8 0.3 0.0016 16.9 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EXF74448.1 - 0.023 13.7 0.1 0.35 9.8 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EXF74448.1 - 0.024 13.7 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EXF74448.1 - 0.04 12.8 0.0 0.083 11.7 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 EXF74448.1 - 0.055 13.8 0.0 0.42 11.0 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF74448.1 - 0.087 11.9 0.8 0.2 10.7 0.2 1.7 2 0 0 2 2 2 0 Thi4 family Glyco_hydro_43 PF04616.9 EXF74449.1 - 0.0011 18.1 1.9 0.0024 16.9 1.3 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 EXF74449.1 - 0.002 17.5 0.2 0.0051 16.2 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain DUF846 PF05832.7 EXF74450.1 - 0.11 12.1 1.5 0.19 11.3 0.3 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF846) FAM220 PF15487.1 EXF74451.1 - 0.42 9.9 11.7 0.82 8.9 0.8 2.5 2 0 0 2 2 2 0 FAM220 family DUF2456 PF10445.4 EXF74452.1 - 6.2e-13 48.4 0.3 1.3e-12 47.4 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2456) Ligase_CoA PF00549.14 EXF74454.1 - 3.2e-17 62.5 0.3 6e-17 61.6 0.2 1.5 1 0 0 1 1 1 1 CoA-ligase CoA_binding PF02629.14 EXF74454.1 - 4.2e-15 56.0 14.4 5.5e-11 42.8 0.1 3.3 3 1 0 4 4 4 2 CoA binding domain Succ_CoA_lig PF13607.1 EXF74454.1 - 6.5e-09 35.5 0.0 1.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain Fungal_trans PF04082.13 EXF74455.1 - 9.9e-27 93.4 0.3 1.5e-26 92.8 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF74455.1 - 2.3e-05 24.1 12.3 3.8e-05 23.5 8.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pkinase PF00069.20 EXF74456.1 - 1.1e-14 54.1 0.0 2.4e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF74456.1 - 3.6e-05 22.9 0.0 7.3e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Sep15_SelM PF08806.6 EXF74456.1 - 0.11 12.3 0.1 0.22 11.2 0.1 1.5 1 0 0 1 1 1 0 Sep15/SelM redox domain Pkinase PF00069.20 EXF74457.1 - 4.9e-24 84.8 0.0 7.6e-24 84.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF74457.1 - 3.1e-16 59.2 0.0 4.6e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EXF74457.1 - 0.063 12.3 0.3 0.83 8.6 0.0 2.6 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gln-synt_C PF00120.19 EXF74458.1 - 3.7e-52 177.0 0.0 5.8e-52 176.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Amidohydro_2 PF04909.9 EXF74458.1 - 9.4e-29 100.8 0.1 1.9e-28 99.8 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase DSBA PF01323.15 EXF74459.1 - 9.7e-13 48.0 0.1 1.1e-12 47.9 0.1 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Prion PF00377.13 EXF74459.1 - 0.082 12.6 0.2 0.15 11.7 0.1 1.4 1 1 0 1 1 1 0 Prion/Doppel alpha-helical domain Amidohydro_3 PF07969.6 EXF74460.1 - 8.6e-56 189.8 0.4 1e-55 189.6 0.3 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EXF74460.1 - 5.8e-08 32.4 0.0 2.2e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 EXF74460.1 - 9e-08 32.4 4.2 0.00052 20.1 0.0 3.3 3 1 0 3 3 3 2 Amidohydrolase Amidohydro_1 PF01979.15 EXF74460.1 - 2.1e-06 27.6 0.1 0.0023 17.6 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family Aldedh PF00171.17 EXF74461.1 - 1.2e-180 600.7 1.4 1.5e-180 600.5 1.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4066 PF13278.1 EXF74461.1 - 7.1e-28 96.9 0.0 1.6e-27 95.7 0.0 1.7 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EXF74461.1 - 3.8e-11 42.6 0.0 1e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 DJ-1/PfpI family Epimerase PF01370.16 EXF74462.1 - 1.7e-13 50.5 0.2 3.7e-08 33.1 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EXF74462.1 - 2.4e-10 40.0 0.4 4.5e-10 39.1 0.2 1.5 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EXF74462.1 - 3.8e-09 36.7 1.4 1.1e-08 35.2 1.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EXF74462.1 - 1.4e-07 30.5 0.1 3.4e-07 29.2 0.1 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EXF74462.1 - 3.3e-07 29.5 0.5 1.9e-06 26.9 0.3 2.1 1 1 0 1 1 1 1 Male sterility protein Semialdhyde_dh PF01118.19 EXF74462.1 - 7.2e-07 29.5 0.2 1.6e-06 28.4 0.1 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 EXF74462.1 - 0.00024 20.1 0.1 0.018 13.9 0.1 2.2 2 0 0 2 2 2 1 RmlD substrate binding domain Saccharop_dh PF03435.13 EXF74462.1 - 0.0018 17.3 0.2 0.0027 16.7 0.2 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase DXP_reductoisom PF02670.11 EXF74462.1 - 0.027 14.9 0.7 0.15 12.5 0.0 2.1 2 1 1 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Polysacc_synt_2 PF02719.10 EXF74462.1 - 0.052 12.4 0.1 0.092 11.6 0.1 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DapB_N PF01113.15 EXF74462.1 - 0.075 12.9 0.2 0.14 12.0 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Aminotran_3 PF00202.16 EXF74463.1 - 1.7e-77 260.5 0.0 2.1e-77 260.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Fungal_trans_2 PF11951.3 EXF74464.1 - 4.8e-40 137.3 9.0 7.2e-40 136.7 6.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF74464.1 - 1.1e-09 38.0 4.5 1.8e-09 37.3 3.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHDPS PF00701.17 EXF74465.1 - 4e-59 199.6 0.0 4.5e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family FMN_dh PF01070.13 EXF74466.1 - 1.9e-111 372.3 0.0 2.3e-111 372.1 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EXF74466.1 - 3.8e-06 26.0 1.0 7.5e-06 25.0 0.1 1.9 3 0 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EXF74466.1 - 0.00044 19.2 0.1 0.0015 17.4 0.0 1.9 3 0 0 3 3 3 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EXF74466.1 - 0.0019 17.5 0.1 0.018 14.3 0.0 2.1 1 1 0 2 2 2 1 Histidine biosynthesis protein ThiG PF05690.9 EXF74466.1 - 0.0072 15.4 0.0 0.27 10.2 0.0 2.7 3 0 0 3 3 3 1 Thiazole biosynthesis protein ThiG DHO_dh PF01180.16 EXF74466.1 - 0.05 12.5 0.1 0.094 11.6 0.1 1.4 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase NMO PF03060.10 EXF74466.1 - 0.065 12.3 0.4 0.1 11.7 0.3 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase Aldedh PF00171.17 EXF74467.1 - 8.9e-134 446.2 0.1 1e-133 446.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EXF74467.1 - 0.05 12.3 0.0 0.074 11.7 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) AA_permease PF00324.16 EXF74468.1 - 4.7e-104 348.3 40.8 5.3e-104 348.2 28.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF74468.1 - 1.7e-26 92.7 46.8 2.1e-26 92.4 32.4 1.0 1 0 0 1 1 1 1 Amino acid permease Sigma70_r4 PF04545.11 EXF74469.1 - 0.00023 20.3 0.0 0.00035 19.8 0.0 1.2 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_23 PF13384.1 EXF74469.1 - 0.00062 19.3 0.1 0.0015 18.0 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EXF74469.1 - 0.0015 17.9 0.0 0.0031 16.9 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_29 PF13551.1 EXF74469.1 - 0.0077 16.3 0.0 0.02 15.0 0.0 1.7 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.1 EXF74469.1 - 0.016 15.1 0.1 0.032 14.2 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain Abhydrolase_6 PF12697.2 EXF74470.1 - 4e-32 111.9 0.0 6.2e-32 111.3 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF74470.1 - 2.1e-14 53.5 0.0 1.5e-13 50.7 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF74470.1 - 1.2e-10 41.3 0.0 1.2e-09 38.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Chlorophyllase2 PF12740.2 EXF74470.1 - 4.3e-05 22.5 0.1 0.00023 20.1 0.0 2.0 2 1 0 2 2 2 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 EXF74470.1 - 4.3e-05 23.2 0.0 8.5e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase PF07224.6 EXF74470.1 - 8.5e-05 21.4 0.0 0.00024 19.9 0.0 1.7 2 0 0 2 2 2 1 Chlorophyllase AXE1 PF05448.7 EXF74470.1 - 0.0012 17.4 0.0 0.0039 15.7 0.0 1.7 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Ndr PF03096.9 EXF74470.1 - 0.0019 16.7 0.0 0.003 16.1 0.0 1.2 1 0 0 1 1 1 1 Ndr family DLH PF01738.13 EXF74470.1 - 0.014 14.6 0.0 0.25 10.5 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family p450 PF00067.17 EXF74471.1 - 1.1e-71 241.7 0.0 1.6e-71 241.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF3989 PF13150.1 EXF74471.1 - 1.1 8.8 2.9 0.82 9.1 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) Mid2 PF04478.7 EXF74472.1 - 0.36 10.2 2.3 0.82 9.0 1.6 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DnaJ PF00226.26 EXF74473.1 - 9.1e-21 73.3 1.4 1.4e-20 72.8 1.0 1.3 1 0 0 1 1 1 1 DnaJ domain Porin_3 PF01459.17 EXF74474.1 - 1.1e-58 198.7 8.6 1.6e-58 198.1 6.0 1.2 1 1 0 1 1 1 1 Eukaryotic porin Asn_synthase PF00733.16 EXF74475.1 - 4.1e-70 236.1 0.0 5.6e-70 235.7 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EXF74475.1 - 5.3e-40 136.0 0.0 8.6e-40 135.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EXF74475.1 - 2.2e-31 108.5 0.0 5.8e-31 107.2 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EXF74475.1 - 9.9e-10 38.0 0.0 1.8e-09 37.1 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EXF74475.1 - 6e-05 21.9 0.0 0.047 12.3 0.0 2.9 1 1 2 3 3 3 2 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EXF74475.1 - 0.00057 18.8 0.0 0.0021 17.0 0.0 1.8 1 1 0 1 1 1 1 NAD synthase UQ_con PF00179.21 EXF74476.1 - 3.5e-49 165.8 0.1 3.9e-49 165.6 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EXF74476.1 - 8.8e-05 22.2 0.0 0.0001 22.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EXF74476.1 - 0.011 15.6 1.8 0.022 14.6 1.3 1.8 1 1 0 1 1 1 0 RWD domain Pex19 PF04614.7 EXF74477.1 - 4.7e-71 239.3 19.1 4.7e-71 239.3 13.3 1.7 1 1 1 2 2 2 1 Pex19 protein family ARL2_Bind_BART PF11527.3 EXF74477.1 - 0.0093 15.7 0.2 0.0093 15.7 0.1 2.6 3 1 0 3 3 3 1 The ARF-like 2 binding protein BART ABC_tran_2 PF12848.2 EXF74477.1 - 0.12 12.2 6.1 0.36 10.7 0.8 2.8 2 0 0 2 2 2 0 ABC transporter ABC1 PF03109.11 EXF74479.1 - 3.1e-31 107.8 0.0 5.6e-31 106.9 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Con-6 PF10346.4 EXF74480.1 - 3.5e-29 99.9 5.3 7.5e-16 57.2 0.2 2.1 2 0 0 2 2 2 2 Conidiation protein 6 SpoIIIAH PF12685.2 EXF74480.1 - 0.01 15.3 1.8 0.46 9.9 0.1 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein Toxin_52 PF15605.1 EXF74480.1 - 0.11 12.3 1.7 1 9.2 0.1 2.2 1 1 0 2 2 2 0 Putative toxin 52 DUF1542 PF07564.6 EXF74480.1 - 0.53 10.3 4.2 10 6.1 0.2 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) UPF0546 PF10639.4 EXF74481.1 - 2e-37 127.4 0.2 2.7e-37 127.0 0.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family UPF0546 EamA PF00892.15 EXF74481.1 - 0.002 18.1 4.0 0.02 14.9 2.3 2.2 2 0 0 2 2 2 1 EamA-like transporter family EmrE PF13536.1 EXF74481.1 - 1.3 9.2 8.2 0.047 13.8 1.8 1.6 2 0 0 2 2 2 0 Multidrug resistance efflux transporter DUF2011 PF09428.5 EXF74482.1 - 0.039 13.8 0.0 0.088 12.6 0.0 1.6 1 1 0 1 1 1 0 Fungal protein of unknown function (DUF2011) DUF4298 PF14131.1 EXF74482.1 - 0.077 12.8 0.1 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) Proteasome PF00227.21 EXF74483.1 - 1.2e-45 155.1 0.0 1.6e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EXF74483.1 - 1.8e-13 49.5 0.2 3.8e-13 48.4 0.2 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF550 PF04447.7 EXF74483.1 - 0.033 13.7 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF550) SCP2 PF02036.12 EXF74483.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 SCP-2 sterol transfer family DUF2373 PF10180.4 EXF74484.1 - 4.3e-21 74.2 0.2 6.9e-21 73.5 0.1 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) HHV6-IE PF03753.8 EXF74484.1 - 4.2 4.7 21.2 6.8 4.0 14.7 1.3 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein PhyH PF05721.8 EXF74485.1 - 3.8e-62 210.0 0.0 4.9e-62 209.7 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 EXF74485.1 - 0.084 13.1 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Claudin_2 PF13903.1 EXF74486.1 - 1.1e-06 28.4 7.6 3.8e-06 26.7 5.4 1.7 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF1772 PF08592.6 EXF74486.1 - 0.045 13.4 0.2 0.045 13.4 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) stn_TNFRSF12A PF12191.3 EXF74486.1 - 0.071 13.1 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain SIS PF01380.17 EXF74487.1 - 4.3e-09 36.0 0.3 2.2e-08 33.7 0.2 2.0 1 1 0 1 1 1 1 SIS domain SIS_2 PF13580.1 EXF74487.1 - 0.062 13.0 0.1 0.3 10.7 0.0 2.1 1 1 1 2 2 2 0 SIS domain C2 PF00168.25 EXF74488.1 - 2.2e-13 49.8 0.0 4.3e-13 48.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain Peptidase_M24 PF00557.19 EXF74489.1 - 4.3e-39 134.2 0.0 5.6e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 NST1 PF13945.1 EXF74489.1 - 0.097 12.7 0.6 0.14 12.2 0.4 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator CDC45 PF02724.9 EXF74489.1 - 0.12 10.3 2.0 0.16 9.9 1.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Med3 PF11593.3 EXF74489.1 - 0.2 10.8 3.2 0.31 10.2 2.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Nop14 PF04147.7 EXF74489.1 - 0.57 8.0 4.1 0.81 7.5 2.8 1.1 1 0 0 1 1 1 0 Nop14-like family Ank_2 PF12796.2 EXF74490.1 - 4e-31 107.2 1.4 4.6e-14 52.5 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EXF74490.1 - 4.6e-23 79.8 11.0 0.00079 19.1 0.1 7.7 7 1 1 8 8 7 5 Ankyrin repeat Ank_3 PF13606.1 EXF74490.1 - 1.9e-16 58.5 6.4 0.41 11.0 0.0 8.7 8 1 1 9 9 8 5 Ankyrin repeat Ank_4 PF13637.1 EXF74490.1 - 7.6e-16 58.1 1.9 4.9e-05 23.7 0.0 5.3 4 1 1 5 5 5 3 Ankyrin repeats (many copies) NACHT PF05729.7 EXF74490.1 - 9.3e-11 41.6 0.0 2e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 NACHT domain Ank_5 PF13857.1 EXF74490.1 - 3.2e-08 33.5 4.4 0.31 11.3 0.0 5.9 2 2 3 5 5 5 3 Ankyrin repeats (many copies) AAA_16 PF13191.1 EXF74490.1 - 0.00037 20.5 0.0 0.0064 16.4 0.0 2.9 3 0 0 3 3 3 1 AAA ATPase domain PNP_UDP_1 PF01048.15 EXF74490.1 - 0.00052 19.0 0.1 0.002 17.1 0.0 1.9 2 0 0 2 2 2 1 Phosphorylase superfamily RNA_helicase PF00910.17 EXF74490.1 - 0.0054 16.8 1.1 0.29 11.3 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA PF00004.24 EXF74490.1 - 0.011 15.9 0.0 0.042 14.0 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EXF74490.1 - 0.02 13.7 0.1 0.092 11.5 0.1 2.0 1 1 0 1 1 1 0 NB-ARC domain KaiC PF06745.8 EXF74490.1 - 0.036 13.1 0.0 0.069 12.2 0.0 1.4 1 0 0 1 1 1 0 KaiC RTTN_N PF14726.1 EXF74490.1 - 0.04 14.4 0.1 0.31 11.6 0.1 2.5 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning AAA_14 PF13173.1 EXF74490.1 - 0.044 13.6 0.0 0.53 10.1 0.0 2.5 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EXF74490.1 - 0.058 12.4 0.1 0.41 9.7 0.0 2.3 3 0 0 3 3 3 0 Zeta toxin AAA_22 PF13401.1 EXF74490.1 - 0.12 12.4 0.0 0.41 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EXF74490.1 - 0.16 11.6 0.0 0.39 10.3 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase RRM_1 PF00076.17 EXF74491.1 - 4.1e-19 67.9 0.2 2.3e-11 43.1 0.0 4.1 3 1 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF74491.1 - 5.2e-17 61.5 0.0 1.7e-08 34.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF74491.1 - 0.0094 15.7 0.0 0.77 9.6 0.0 3.2 4 0 0 4 4 4 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cut8_C PF08559.5 EXF74492.1 - 4.3e-44 149.8 0.0 5.6e-44 149.4 0.0 1.1 1 0 0 1 1 1 1 Cut8 six-helix bundle Cut8_M PF14483.1 EXF74492.1 - 3.8e-15 55.4 0.7 7.2e-15 54.5 0.5 1.5 1 0 0 1 1 1 1 Cut8 dimerisation domain Cut8_N PF14482.1 EXF74492.1 - 8.2e-08 32.1 5.4 1.5e-07 31.2 3.8 1.4 1 0 0 1 1 1 1 Cut8 proteasome-binding domain AP_endonuc_2 PF01261.19 EXF74492.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Rad52_Rad22 PF04098.10 EXF74493.1 - 8.3e-61 204.2 0.0 1.2e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein OstA PF03968.9 EXF74494.1 - 0.11 12.4 0.0 0.33 10.9 0.0 1.7 1 0 0 1 1 1 0 OstA-like protein DUF2824 PF11039.3 EXF74496.1 - 0.13 11.9 0.8 5.4 6.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2824) DUF4267 PF14087.1 EXF74496.1 - 0.36 10.4 4.9 0.2 11.2 0.9 2.5 2 2 0 2 2 2 0 Domain of unknown function (DUF4267) DUF3611 PF12263.3 EXF74496.1 - 1.2 8.4 8.6 0.027 13.8 1.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) UTP15_C PF09384.5 EXF74497.1 - 7.2e-41 139.3 0.0 1.3e-40 138.4 0.0 1.4 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.27 EXF74497.1 - 1.4e-26 91.3 9.9 3.9e-10 39.2 0.1 4.7 6 0 0 6 6 6 3 WD domain, G-beta repeat Pinin_SDK_memA PF04696.8 EXF74497.1 - 0.0048 16.5 1.0 0.0082 15.7 0.7 1.3 1 0 0 1 1 1 1 pinin/SDK/memA/ protein conserved region Gln-synt_C PF00120.19 EXF74498.1 - 1.5e-60 204.5 0.0 1.8e-60 204.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EXF74498.1 - 4.6e-20 70.9 0.0 9.9e-20 69.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain DUF4462 PF14692.1 EXF74500.1 - 0.035 13.3 0.1 0.1 11.8 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4462) Attractin PF08037.6 EXF74501.1 - 0.29 10.9 4.8 0.93 9.3 3.4 1.9 1 0 0 1 1 1 0 Attractin family FrhB_FdhB_C PF04432.8 EXF74502.1 - 0.033 13.5 0.5 2.4 7.5 0.0 2.3 2 0 0 2 2 2 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus FYVE_2 PF02318.11 EXF74502.1 - 5.4 6.9 12.6 1.6 8.6 4.0 3.0 3 0 0 3 3 3 0 FYVE-type zinc finger MRP-L20 PF12824.2 EXF74503.1 - 3.3e-54 183.2 1.2 4e-54 183.0 0.9 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 Neugrin PF06413.6 EXF74503.1 - 0.0015 18.4 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 Neugrin HTH_11 PF08279.7 EXF74503.1 - 0.051 13.2 0.0 0.18 11.4 0.0 1.9 2 0 0 2 2 2 0 HTH domain YL1 PF05764.8 EXF74504.1 - 0.69 9.4 3.9 1.2 8.7 2.7 1.2 1 0 0 1 1 1 0 YL1 nuclear protein OB_NTP_bind PF07717.11 EXF74505.1 - 1.1e-27 96.1 0.0 2.5e-27 94.9 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EXF74505.1 - 2.3e-23 82.1 0.1 2.3e-23 82.1 0.1 2.9 4 0 0 4 4 4 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EXF74505.1 - 3.1e-13 49.3 0.0 9.3e-13 47.8 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EXF74505.1 - 2.7e-05 24.3 0.3 8.9e-05 22.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 EXF74505.1 - 0.0002 20.8 0.1 0.00068 19.1 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase T2SE PF00437.15 EXF74505.1 - 0.00074 18.5 0.0 0.0018 17.2 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 EXF74505.1 - 0.029 13.8 0.2 0.069 12.5 0.2 1.7 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.1 EXF74505.1 - 0.031 14.1 1.5 0.31 10.9 0.1 3.0 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EXF74505.1 - 0.34 11.2 0.0 0.34 11.2 0.0 2.3 3 1 0 3 3 3 0 ABC transporter DnaJ PF00226.26 EXF74506.1 - 2.8e-26 91.0 3.2 4.5e-26 90.3 2.2 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EXF74506.1 - 3.6e-14 52.5 18.1 6.5e-14 51.7 12.6 1.4 1 0 0 1 1 1 1 DnaJ central domain CTDII PF01556.13 EXF74506.1 - 2.2e-13 49.8 0.0 8.7e-13 47.9 0.0 2.0 2 0 0 2 2 2 1 DnaJ C terminal domain HypA PF01155.14 EXF74506.1 - 0.0088 15.7 7.6 0.2 11.3 0.4 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family DUF4366 PF14283.1 EXF74507.1 - 0.0001 21.8 3.2 0.3 10.4 0.0 3.3 4 0 0 4 4 4 2 Domain of unknown function (DUF4366) DUF3824 PF12868.2 EXF74507.1 - 0.0054 17.6 10.4 0.0054 17.6 7.2 10.9 6 5 4 10 10 10 2 Domain of unknwon function (DUF3824) MFS_1 PF07690.11 EXF74508.1 - 1.1e-42 146.0 39.9 1.1e-42 146.0 27.7 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF74508.1 - 1.7e-13 49.9 23.7 2e-12 46.4 9.9 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter GPI-anchored PF10342.4 EXF74509.1 - 8.9e-06 26.1 2.8 8.9e-06 26.1 1.9 1.9 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Podoplanin PF05808.6 EXF74509.1 - 0.039 13.5 0.2 0.061 12.8 0.1 1.3 1 0 0 1 1 1 0 Podoplanin Saccharop_dh PF03435.13 EXF74510.1 - 2.2e-99 333.0 0.0 2.9e-99 332.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EXF74510.1 - 2.6e-07 30.7 0.0 3.9e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EXF74510.1 - 0.0068 16.8 0.0 0.013 15.9 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TatD_DNase PF01026.16 EXF74511.1 - 1.4e-38 132.5 0.0 2.1e-38 132.0 0.0 1.2 1 1 0 1 1 1 1 TatD related DNase HAD_2 PF13419.1 EXF74512.1 - 2.3e-30 106.1 0.0 3e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Ten1 PF12658.2 EXF74513.1 - 4.9e-32 110.2 0.0 5.7e-32 110.0 0.0 1.1 1 0 0 1 1 1 1 Telomere capping, CST complex subunit Ten1_2 PF15490.1 EXF74513.1 - 5.5e-05 22.7 0.0 5.8e-05 22.6 0.0 1.1 1 0 0 1 1 1 1 Telomere-capping, CST complex subunit Rep_fac-A_3 PF08661.6 EXF74513.1 - 0.057 13.3 0.0 0.075 12.9 0.0 1.2 1 0 0 1 1 1 0 Replication factor A protein 3 Snf7 PF03357.16 EXF74514.1 - 4.6e-29 100.9 19.5 4.6e-29 100.9 13.5 2.0 1 1 1 2 2 2 1 Snf7 NPP1 PF05630.6 EXF74514.1 - 0.014 15.1 0.3 0.019 14.6 0.2 1.2 1 0 0 1 1 1 0 Necrosis inducing protein (NPP1) Allexi_40kDa PF05549.6 EXF74514.1 - 0.8 8.9 6.6 1.2 8.4 4.5 1.4 1 1 0 1 1 1 0 Allexivirus 40kDa protein BLOC1_2 PF10046.4 EXF74514.1 - 3.6 7.7 12.7 1.4 9.1 0.6 3.4 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 VASP_tetra PF08776.6 EXF74514.1 - 5.4 6.4 8.1 14 5.0 2.3 2.8 3 0 0 3 3 3 0 VASP tetramerisation domain Cu-oxidase_3 PF07732.10 EXF74517.1 - 1.3e-39 134.5 4.1 1.3e-39 134.5 2.8 3.0 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EXF74517.1 - 4.8e-35 120.0 1.3 4.8e-35 120.0 0.9 3.1 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EXF74517.1 - 6.7e-34 117.0 0.6 1.6e-33 115.8 0.0 2.0 2 0 0 2 2 2 1 Multicopper oxidase MFS_1 PF07690.11 EXF74518.1 - 2e-34 118.8 25.0 2e-34 118.8 17.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF74518.1 - 5.2e-15 54.9 14.9 6.9e-15 54.5 10.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF3938 PF13074.1 EXF74518.1 - 0.027 14.3 0.7 0.1 12.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3938) ALMT PF11744.3 EXF74518.1 - 0.049 12.2 1.6 0.078 11.6 1.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Trp_oprn_chp PF09534.5 EXF74518.1 - 0.53 9.8 7.6 0.06 12.9 1.1 2.2 2 0 0 2 2 2 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) G_glu_transpept PF01019.16 EXF74519.1 - 3.7e-146 487.6 0.1 4.3e-146 487.3 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Glutaredoxin PF00462.19 EXF74520.1 - 1.5e-15 56.9 0.0 2.7e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin Flavoprotein PF02441.14 EXF74521.1 - 9.3e-41 138.5 0.2 1.4e-40 137.9 0.1 1.2 1 0 0 1 1 1 1 Flavoprotein Mpp10 PF04006.7 EXF74522.1 - 5.9e-90 302.3 84.8 2.4e-87 293.7 58.7 2.1 1 1 0 1 1 1 1 Mpp10 protein CIAPIN1 PF05093.8 EXF74523.1 - 1.5e-34 118.0 5.0 2.4e-34 117.3 3.4 1.2 1 0 0 1 1 1 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Peptidase_S10 PF00450.17 EXF74524.1 - 2.2e-111 372.9 0.1 2.7e-111 372.6 0.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase RNA_Me_trans PF04252.8 EXF74525.1 - 2.1e-37 128.4 0.0 2.5e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase tRNA_m1G_MT PF01746.16 EXF74525.1 - 0.064 12.8 0.0 2.9 7.4 0.0 2.1 2 0 0 2 2 2 0 tRNA (Guanine-1)-methyltransferase DUF1680 PF07944.7 EXF74526.1 - 8.6e-103 344.3 0.0 1.4e-102 343.6 0.0 1.3 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) TPR_19 PF14559.1 EXF74526.1 - 0.1 12.9 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-CCCH PF00642.19 EXF74527.1 - 8.2e-05 22.1 2.7 0.00015 21.3 1.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Sec1 PF00995.18 EXF74528.1 - 1e-149 499.7 0.0 1.3e-149 499.5 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Gpi1 PF05024.10 EXF74529.1 - 2.3e-63 213.3 8.7 3.9e-63 212.5 6.1 1.4 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) UPF0203 PF05254.7 EXF74529.1 - 6.5e-27 93.1 1.3 1.2e-26 92.3 0.9 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) 7tm_1 PF00001.16 EXF74529.1 - 0.0022 17.1 3.3 0.0031 16.7 0.6 2.3 3 0 0 3 3 3 1 7 transmembrane receptor (rhodopsin family) COX17 PF05051.8 EXF74529.1 - 0.18 11.8 0.4 0.39 10.7 0.3 1.5 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 EXF74529.1 - 0.81 9.5 3.3 3.1 7.6 0.1 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like DNA_pol_A_exo1 PF01612.15 EXF74530.1 - 3.8e-40 137.2 0.3 6.1e-40 136.5 0.2 1.3 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EXF74530.1 - 2e-21 76.0 0.6 5.5e-21 74.6 0.1 2.1 2 0 0 2 2 2 1 PMC2NT (NUC016) domain HRDC PF00570.18 EXF74530.1 - 8.8e-12 44.5 0.4 4.2e-11 42.3 0.0 2.4 2 1 1 3 3 3 1 HRDC domain Borrelia_P83 PF05262.6 EXF74530.1 - 0.065 11.4 40.4 0.11 10.8 28.0 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein 2-Hacid_dh_C PF02826.14 EXF74531.1 - 1.7e-38 131.5 0.1 1.7e-36 125.0 0.1 2.6 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EXF74531.1 - 3.7e-18 65.2 0.1 5e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EXF74531.1 - 0.00032 20.5 1.2 0.00099 18.9 0.8 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EXF74531.1 - 0.0035 17.7 0.7 0.016 15.5 0.5 2.2 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ADH_zinc_N PF00107.21 EXF74531.1 - 0.011 15.2 0.2 0.074 12.5 0.1 2.4 2 1 0 2 2 2 0 Zinc-binding dehydrogenase AdoHcyase_NAD PF00670.16 EXF74531.1 - 0.013 15.3 0.3 8 6.2 0.1 2.8 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.7 EXF74531.1 - 0.013 14.8 0.2 0.026 13.8 0.1 1.4 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Saccharop_dh PF03435.13 EXF74531.1 - 0.043 12.7 0.1 0.071 12.0 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase TrkA_N PF02254.13 EXF74531.1 - 0.078 12.9 0.4 0.34 10.9 0.0 2.1 3 0 0 3 3 3 0 TrkA-N domain Methyltransf_23 PF13489.1 EXF74534.1 - 9.8e-20 70.8 0.0 1.5e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF74534.1 - 4.2e-08 33.5 0.0 7.7e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF74534.1 - 7.7e-08 32.0 0.0 8.2e-07 28.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF74534.1 - 3.9e-07 30.6 0.0 3.6e-06 27.5 0.0 2.3 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF74534.1 - 7.7e-07 29.5 0.0 6.2e-06 26.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF74534.1 - 0.00024 21.3 0.0 0.0005 20.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF74534.1 - 0.007 15.7 0.0 0.022 14.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain CMAS PF02353.15 EXF74534.1 - 0.013 14.6 0.0 0.026 13.5 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_17 PF12692.2 EXF74534.1 - 0.06 13.0 0.0 7 6.3 0.0 2.3 2 0 0 2 2 2 0 S-adenosyl-L-methionine methyltransferase PrmA PF06325.8 EXF74534.1 - 0.067 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EXF74534.1 - 0.076 12.0 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Etmic-2 PF06670.6 EXF74534.1 - 0.27 9.8 2.6 0.39 9.3 1.8 1.2 1 0 0 1 1 1 0 Microneme protein Etmic-2 HpcH_HpaI PF03328.9 EXF74536.1 - 1.8e-27 95.6 0.0 2.5e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PK PF00224.16 EXF74536.1 - 0.0016 17.1 0.1 0.0023 16.6 0.0 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain DmpG_comm PF07836.6 EXF74536.1 - 0.12 11.8 0.1 3.6 7.0 0.1 2.5 1 1 0 1 1 1 0 DmpG-like communication domain Aminotran_1_2 PF00155.16 EXF74537.1 - 2.1e-73 247.4 0.0 2.3e-73 247.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EXF74537.1 - 0.049 12.1 0.0 0.065 11.7 0.0 1.2 1 0 0 1 1 1 0 Alanine-glyoxylate amino-transferase RICTOR_N PF14664.1 EXF74537.1 - 0.065 11.8 0.0 0.088 11.3 0.0 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Methyltransf_2 PF00891.13 EXF74538.1 - 4.3e-28 98.1 0.0 6.8e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase MFS_1 PF07690.11 EXF74541.1 - 4.3e-22 78.3 74.0 2.7e-21 75.6 34.4 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Amidohydro_1 PF01979.15 EXF74542.1 - 2.8e-37 129.1 1.1 5e-37 128.3 0.1 1.7 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_4 PF13147.1 EXF74542.1 - 1.9e-16 60.9 0.0 6.3e-15 55.9 0.0 2.4 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EXF74542.1 - 8.9e-15 54.2 0.0 3.9e-14 52.2 0.0 2.2 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EXF74542.1 - 1.2e-14 54.4 0.7 5e-12 45.7 0.0 2.8 1 1 1 2 2 2 2 Amidohydrolase family Plant_NMP1 PF06694.6 EXF74542.1 - 0.13 11.1 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) DPBB_1 PF03330.13 EXF74543.1 - 3.8e-10 39.6 1.4 2.2e-09 37.1 0.2 2.6 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EXF74543.1 - 0.00013 21.6 2.1 0.00021 20.9 0.1 2.0 2 0 0 2 2 2 1 Barwin family Mo-co_dimer PF03404.11 EXF74543.1 - 0.05 13.2 0.1 0.083 12.5 0.1 1.4 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain BNR PF02012.15 EXF74543.1 - 0.068 13.0 0.1 0.33 10.9 0.1 2.3 1 0 0 1 1 1 0 BNR/Asp-box repeat Toxin_28 PF08115.6 EXF74543.1 - 0.35 10.5 8.8 0.17 11.5 2.4 2.4 2 0 0 2 2 2 0 SFI toxin family Fungal_trans PF04082.13 EXF74544.1 - 6.1e-20 71.1 0.0 3.5e-19 68.6 0.0 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF74544.1 - 1.1e-08 34.8 13.3 2e-08 34.0 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RasGAP_C PF03836.10 EXF74544.1 - 0.24 11.0 0.0 0.43 10.2 0.0 1.3 1 0 0 1 1 1 0 RasGAP C-terminus AA_permease PF00324.16 EXF74545.1 - 1.8e-108 362.9 44.3 2.2e-108 362.6 30.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF74545.1 - 1.4e-34 119.4 46.5 1.6e-34 119.1 32.2 1.1 1 0 0 1 1 1 1 Amino acid permease ADH_zinc_N PF00107.21 EXF74546.1 - 9.7e-13 47.8 0.6 2.7e-12 46.3 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF74546.1 - 9e-08 31.8 0.0 1.5e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain zf-LITAF-like PF10601.4 EXF74547.1 - 2.8e-12 46.3 13.9 3.8e-12 45.9 9.6 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Cys_rich_KTR PF14205.1 EXF74547.1 - 0.001 18.4 0.8 0.015 14.7 0.1 2.2 2 0 0 2 2 2 1 Cysteine-rich KTR HET PF06985.6 EXF74548.1 - 3.1e-19 69.5 13.4 5.2e-18 65.5 0.9 3.0 3 1 1 4 4 4 2 Heterokaryon incompatibility protein (HET) Lyase_1 PF00206.15 EXF74549.1 - 2.3e-88 296.3 0.0 3e-88 296.0 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EXF74549.1 - 2.5e-28 97.9 0.0 4.9e-28 97.0 0.0 1.5 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal Transp_cyt_pur PF02133.10 EXF74550.1 - 7.7e-19 67.5 33.6 1.2e-18 66.8 23.3 1.3 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin ILVD_EDD PF00920.16 EXF74551.1 - 5.4e-189 628.9 0.3 6.2e-189 628.7 0.2 1.0 1 0 0 1 1 1 1 Dehydratase family MR_MLE_C PF13378.1 EXF74551.1 - 0.079 12.9 1.0 0.3 11.0 0.0 2.4 2 1 1 3 3 3 0 Enolase C-terminal domain-like Phage_BR0599 PF09356.5 EXF74551.1 - 0.11 12.6 0.0 1 9.5 0.0 2.3 2 0 0 2 2 2 0 Phage conserved hypothetical protein BR0599 Epimerase PF01370.16 EXF74552.1 - 1.8e-26 93.0 0.0 2.4e-26 92.5 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF74552.1 - 8.5e-13 48.7 0.0 7e-12 45.7 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EXF74552.1 - 2.9e-12 45.8 0.0 4.1e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EXF74552.1 - 2.1e-11 43.2 0.0 5.9e-09 35.2 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EXF74552.1 - 1.8e-09 36.8 0.0 2.4e-09 36.5 0.0 1.3 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EXF74552.1 - 5.5e-06 25.4 0.0 1.8e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EXF74552.1 - 0.0096 15.8 0.8 0.24 11.3 0.6 2.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF74552.1 - 0.026 14.1 0.2 5.9 6.5 0.0 2.2 2 0 0 2 2 2 0 KR domain NmrA PF05368.8 EXF74552.1 - 0.078 12.2 0.1 1.3 8.2 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family HATPase_c PF02518.21 EXF74553.1 - 2.1e-28 98.2 0.1 4.2e-28 97.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EXF74553.1 - 1.9e-22 79.0 0.1 5.8e-22 77.4 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 EXF74553.1 - 2.8e-22 78.8 0.1 5.9e-22 77.7 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 EXF74553.1 - 5.7e-19 68.4 0.0 4.8e-11 42.9 0.0 4.2 4 0 0 4 4 4 3 PAS domain PAS_3 PF08447.6 EXF74553.1 - 1.2e-17 63.8 0.3 3e-17 62.5 0.2 1.8 1 0 0 1 1 1 1 PAS fold PAS_4 PF08448.5 EXF74553.1 - 6.5e-13 48.6 0.1 4.4e-06 26.6 0.0 4.6 4 1 0 4 4 4 3 PAS fold PAS PF00989.19 EXF74553.1 - 1.9e-08 34.1 0.0 0.018 14.7 0.0 4.3 4 0 0 4 4 4 2 PAS fold PAS_8 PF13188.1 EXF74553.1 - 9.8e-06 25.2 0.0 0.034 14.0 0.0 3.9 3 0 0 3 3 3 1 PAS domain HATPase_c_3 PF13589.1 EXF74553.1 - 0.0032 17.1 0.0 0.0074 15.9 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.20 EXF74554.1 - 1.3e-25 90.0 0.0 1.8e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF74554.1 - 3.2e-09 36.2 0.0 6.3e-09 35.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase V_ATPase_I PF01496.14 EXF74555.1 - 0.058 11.2 0.5 0.079 10.8 0.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family WEMBL PF05701.6 EXF74555.1 - 0.15 10.5 0.6 0.19 10.1 0.4 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Memo PF01875.12 EXF74556.1 - 3e-74 249.3 0.0 4.5e-74 248.8 0.0 1.2 1 0 0 1 1 1 1 Memo-like protein Ank_5 PF13857.1 EXF74556.1 - 0.00027 21.0 0.0 0.029 14.6 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EXF74556.1 - 0.00043 20.7 0.0 0.2 12.2 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EXF74556.1 - 0.0011 19.2 0.0 0.011 16.1 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EXF74556.1 - 0.0053 16.5 0.3 0.12 12.1 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 EXF74556.1 - 0.17 12.2 0.0 4.8 7.7 0.0 3.0 2 0 0 2 2 2 0 Ankyrin repeat SNARE PF05739.14 EXF74557.1 - 4.7e-11 42.2 6.5 4.7e-11 42.2 4.5 2.9 2 1 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EXF74557.1 - 7.3e-07 29.3 1.5 7.3e-07 29.3 1.1 2.7 2 1 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.1 EXF74557.1 - 0.00072 19.5 1.7 0.00072 19.5 1.2 2.7 1 1 1 2 2 2 1 Syntaxin-like protein Rifin_STEVOR PF02009.11 EXF74557.1 - 0.051 13.2 9.6 0.047 13.3 4.6 2.0 1 1 1 2 2 2 0 Rifin/stevor family Herpes_U30 PF04523.8 EXF74557.1 - 0.093 10.1 3.5 0.13 9.6 2.4 1.1 1 0 0 1 1 1 0 Herpes virus tegument protein U30 V-SNARE PF05008.10 EXF74557.1 - 0.13 12.4 13.1 0.28 11.3 2.3 3.6 3 1 1 4 4 4 0 Vesicle transport v-SNARE protein N-terminus HrpA_pilin PF09589.5 EXF74557.1 - 0.13 12.6 3.7 0.65 10.4 2.4 2.3 1 1 0 1 1 1 0 HrpA pilus formation protein MitMem_reg PF13012.1 EXF74557.1 - 0.21 11.6 4.7 1 9.4 0.2 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Allexi_40kDa PF05549.6 EXF74557.1 - 0.74 9.0 7.0 1 8.6 0.3 2.2 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF2229 PF09989.4 EXF74557.1 - 0.99 8.8 3.2 0.96 8.8 0.3 2.0 1 1 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) FAD_binding_4 PF01565.18 EXF74558.1 - 5.6e-26 90.6 2.7 2.2e-25 88.7 1.6 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EXF74558.1 - 0.0032 17.3 0.5 0.0083 16.0 0.1 1.9 2 0 0 2 2 2 1 Berberine and berberine like zf-Apc11 PF12861.2 EXF74560.1 - 5.3e-45 151.1 10.8 8.6e-45 150.5 7.5 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EXF74560.1 - 5.3e-32 109.7 11.1 9.5e-32 108.9 7.7 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EXF74560.1 - 2.2e-08 33.7 15.1 9.1e-08 31.8 10.5 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EXF74560.1 - 8.3e-05 22.1 11.8 0.00028 20.4 8.2 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EXF74560.1 - 0.00015 21.7 12.1 0.00064 19.6 8.4 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EXF74560.1 - 0.00048 19.7 12.5 0.0065 16.1 8.6 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EXF74560.1 - 0.01 15.3 13.0 0.1 12.2 7.2 2.3 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EXF74560.1 - 0.012 15.4 10.4 0.02 14.7 6.1 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EXF74560.1 - 0.013 15.4 15.1 0.15 12.0 10.5 2.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.3 EXF74560.1 - 0.076 12.5 5.6 0.17 11.4 3.9 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.1 EXF74560.1 - 0.14 11.9 16.9 0.85 9.3 11.0 2.8 2 1 1 3 3 3 0 zinc-RING finger domain zf-HIT PF04438.11 EXF74560.1 - 1.3 8.7 7.7 2.8 7.6 2.7 2.4 2 0 0 2 2 2 0 HIT zinc finger zf-RING_UBOX PF13445.1 EXF74560.1 - 1.7 8.4 7.6 0.8 9.4 2.3 2.7 2 1 1 3 3 3 0 RING-type zinc-finger zf-RING-like PF08746.6 EXF74560.1 - 3.9 7.5 12.7 14 5.7 8.8 2.0 1 1 0 1 1 1 0 RING-like domain RINGv PF12906.2 EXF74560.1 - 4.9 7.2 11.4 0.67 10.0 4.9 1.9 2 0 0 2 2 2 0 RING-variant domain Opy2 PF09463.5 EXF74560.1 - 7.5 6.7 11.6 24 5.0 4.7 2.5 2 0 0 2 2 2 0 Opy2 protein Rhodanese PF00581.15 EXF74561.1 - 2.2e-21 76.2 0.0 3.2e-12 46.7 0.0 2.2 2 0 0 2 2 2 2 Rhodanese-like domain DAP_epimerase PF01678.14 EXF74561.1 - 0.14 12.0 0.0 0.87 9.5 0.0 2.1 2 0 0 2 2 2 0 Diaminopimelate epimerase Ribosomal_S5 PF00333.15 EXF74562.1 - 2.7e-28 97.4 1.6 2.7e-28 97.4 1.1 1.6 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EXF74562.1 - 4.9e-22 76.9 0.0 9.4e-22 76.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FoP_duplication PF13865.1 EXF74562.1 - 2.3 8.7 14.6 0.13 12.6 6.5 1.6 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Borrelia_P83 PF05262.6 EXF74563.1 - 0.25 9.5 0.1 0.41 8.8 0.1 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein Asp_protease_2 PF13650.1 EXF74564.1 - 0.17 12.4 0.0 0.38 11.2 0.0 1.5 1 0 0 1 1 1 0 Aspartyl protease bZIP_1 PF00170.16 EXF74565.1 - 0.00066 19.5 4.5 0.0011 18.9 3.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor IGR PF09597.5 EXF74566.1 - 2.3e-20 72.2 0.0 4e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 IGR protein motif SNF2_N PF00176.18 EXF74567.1 - 9.5e-56 188.7 0.0 1.6e-55 187.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_3 PF13920.1 EXF74567.1 - 4.3e-09 35.9 10.9 8.3e-09 34.9 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EXF74567.1 - 8e-08 31.8 13.7 1.7e-07 30.7 9.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EXF74567.1 - 2.6e-07 30.3 12.6 5.8e-07 29.2 8.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EXF74567.1 - 1.4e-06 28.1 13.1 3.1e-06 27.0 9.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EXF74567.1 - 4.2e-06 26.7 7.0 1.2e-05 25.3 4.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EXF74567.1 - 3.6e-05 23.3 13.2 7.5e-05 22.3 9.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain IBR PF01485.16 EXF74567.1 - 0.0049 16.7 4.0 0.013 15.3 2.8 1.7 1 0 0 1 1 1 1 IBR domain zf-RING_4 PF14570.1 EXF74567.1 - 0.0057 16.2 7.1 0.014 14.9 4.9 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EXF74567.1 - 0.017 14.6 5.5 0.036 13.6 3.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 EXF74567.1 - 0.041 13.7 10.1 0.093 12.6 7.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EXF74567.1 - 0.057 13.1 10.2 0.19 11.4 7.1 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 EXF74567.1 - 0.32 10.8 6.8 0.66 9.8 4.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Sec10 PF07393.6 EXF74568.1 - 1e-166 556.1 0.0 1.3e-166 555.8 0.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec10 F-box-like PF12937.2 EXF74568.1 - 1.9e-07 30.6 0.1 1e-06 28.3 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EXF74568.1 - 0.0019 17.8 0.0 0.0042 16.7 0.0 1.6 1 0 0 1 1 1 1 F-box domain Pkinase PF00069.20 EXF74569.1 - 2.1e-65 220.4 0.0 2.5e-65 220.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF74569.1 - 1e-35 123.1 0.0 1.4e-35 122.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF74569.1 - 0.00057 18.9 0.0 0.0016 17.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Frag1 PF10277.4 EXF74570.1 - 1.9e-42 145.1 23.0 2.1e-42 145.0 16.0 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family DUF3812 PF12757.2 EXF74571.1 - 1.7e-33 115.2 14.9 1.7e-33 115.2 10.3 4.4 4 2 1 5 5 5 1 Protein of unknown function (DUF3812) Y_phosphatase3 PF13350.1 EXF74572.1 - 1.3e-30 106.7 0.1 9.7e-16 58.4 0.0 2.2 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 EXF74572.1 - 2.9e-07 29.9 0.0 1.1e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EXF74572.1 - 1.5e-06 28.2 0.3 1.5e-06 28.2 0.2 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Myotub-related PF06602.9 EXF74572.1 - 0.0014 17.4 0.1 0.0026 16.5 0.0 1.4 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain DSPc PF00782.15 EXF74572.1 - 0.0024 17.4 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EXF74572.1 - 0.0081 15.5 0.0 0.011 15.0 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Methyltransf_12 PF08242.7 EXF74573.1 - 7.2e-15 55.2 0.1 2.1e-14 53.7 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF74573.1 - 3.9e-11 42.9 0.1 8e-11 41.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF74573.1 - 5.5e-11 42.8 0.0 1.2e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF74573.1 - 3.1e-10 40.6 0.0 7.3e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF74573.1 - 4.3e-10 39.8 0.0 3.6e-09 36.9 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF74573.1 - 1.7e-09 37.4 0.0 2.6e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF74573.1 - 1.5e-05 24.2 0.0 2.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EXF74573.1 - 2.7e-05 23.5 0.0 4.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EXF74573.1 - 3e-05 24.0 0.0 5.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EXF74573.1 - 6e-05 23.8 0.0 0.00014 22.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF3419 PF11899.3 EXF74573.1 - 0.00015 20.6 0.0 0.00021 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) Methyltransf_16 PF10294.4 EXF74573.1 - 0.0016 17.9 0.0 0.0024 17.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_8 PF05148.10 EXF74573.1 - 0.0025 17.4 0.0 0.034 13.7 0.0 2.3 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_32 PF13679.1 EXF74573.1 - 0.015 14.9 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EXF74573.1 - 0.024 13.6 0.0 4.6 6.1 0.0 2.3 1 1 1 2 2 2 0 NNMT/PNMT/TEMT family FmrO PF07091.6 EXF74573.1 - 0.025 13.5 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) TehB PF03848.9 EXF74573.1 - 0.026 13.7 0.0 0.048 12.8 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB PrmA PF06325.8 EXF74573.1 - 0.049 12.7 0.0 0.075 12.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) RrnaAD PF00398.15 EXF74573.1 - 0.081 11.9 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase TPR_11 PF13414.1 EXF74574.1 - 5.6e-12 45.1 4.5 2.3e-06 27.1 0.1 4.5 2 2 2 4 4 4 3 TPR repeat TPR_14 PF13428.1 EXF74574.1 - 2.4e-10 40.1 9.0 0.00015 22.1 0.1 6.2 3 1 4 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 EXF74574.1 - 2.7e-10 40.4 3.6 7.3e-07 29.4 0.4 3.9 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EXF74574.1 - 1.4e-07 32.0 8.6 4e-06 27.3 0.3 3.9 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EXF74574.1 - 3.4e-07 29.6 6.9 0.00011 21.8 0.3 5.2 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EXF74574.1 - 1.5e-06 27.9 0.6 0.0014 18.6 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EXF74574.1 - 5.9e-06 25.6 0.1 0.0039 16.8 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EXF74574.1 - 7.4e-06 25.8 3.8 0.015 15.2 0.8 3.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 EXF74574.1 - 2.3e-05 24.1 0.6 0.00097 18.9 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EXF74574.1 - 6.6e-05 23.1 0.8 0.8 10.3 0.1 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EXF74574.1 - 0.00031 20.2 4.7 0.00033 20.1 0.1 3.3 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 EXF74574.1 - 0.00035 20.6 2.3 0.0016 18.4 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EXF74574.1 - 0.0005 19.6 1.6 0.022 14.5 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Methyltransf_1N PF02870.10 EXF74574.1 - 0.0025 18.3 0.0 0.0094 16.5 0.0 2.0 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain Apc3 PF12895.2 EXF74574.1 - 0.0049 16.9 0.2 0.043 13.9 0.1 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.5 EXF74574.1 - 0.0095 14.7 0.0 0.012 14.3 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) PPR_3 PF13812.1 EXF74574.1 - 0.018 15.3 0.3 0.098 12.9 0.0 2.4 2 0 0 2 2 2 0 Pentatricopeptide repeat domain BTAD PF03704.12 EXF74574.1 - 0.023 14.9 3.3 1.8 8.8 0.0 3.2 2 2 0 3 3 3 0 Bacterial transcriptional activator domain Mgr1 PF08602.5 EXF74574.1 - 0.05 12.6 0.0 0.075 12.0 0.0 1.3 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Dimer_Tnp_Tn5 PF02281.11 EXF74574.1 - 0.079 13.0 0.0 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Transposase Tn5 dimerisation domain Polyketide_cyc PF03364.15 EXF74576.1 - 1.1e-26 93.2 0.0 2.7e-26 92.0 0.0 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.4 EXF74576.1 - 2.7e-05 24.3 1.4 9.8e-05 22.5 1.0 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Adaptin_N PF01602.15 EXF74577.1 - 1.1e-72 245.0 0.0 1.8e-72 244.3 0.0 1.3 1 0 0 1 1 1 1 Adaptin N terminal region FCH PF00611.18 EXF74578.1 - 3.1e-17 62.5 0.3 2.1e-16 59.8 0.0 2.6 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain RhoGAP PF00620.22 EXF74578.1 - 4.5e-16 58.8 0.0 1.1e-15 57.5 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain DEP PF00610.16 EXF74578.1 - 2e-13 49.8 0.0 4.5e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF3993 PF13158.1 EXF74578.1 - 0.091 12.5 0.3 0.35 10.6 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3993) Peptidase_M19 PF01244.16 EXF74579.1 - 1.1e-103 346.5 0.0 1.3e-103 346.2 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Amidohydro_2 PF04909.9 EXF74579.1 - 0.013 15.0 0.0 0.026 14.1 0.0 1.6 1 1 0 1 1 1 0 Amidohydrolase Ribosomal_S13 PF00416.17 EXF74580.1 - 8.5e-21 74.4 0.0 1.1e-20 74.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Pro_isomerase PF00160.16 EXF74581.1 - 8.5e-47 159.2 0.6 1.1e-46 158.8 0.4 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Trm112p PF03966.11 EXF74582.1 - 7.2e-19 67.9 0.1 9e-19 67.6 0.1 1.1 1 0 0 1 1 1 1 Trm112p-like protein Zn_ribbon_recom PF13408.1 EXF74582.1 - 0.051 13.8 0.2 0.087 13.1 0.2 1.3 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain ATP-synt_S1 PF05827.7 EXF74583.1 - 1.7e-34 119.4 0.0 5e-33 114.6 0.0 2.1 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) Nop25 PF09805.4 EXF74584.1 - 1.3e-34 119.2 13.0 1.3e-34 119.2 9.0 2.4 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) Nop14 PF04147.7 EXF74584.1 - 0.86 7.4 25.8 1 7.2 17.9 1.0 1 0 0 1 1 1 0 Nop14-like family Tropomyosin_1 PF12718.2 EXF74585.1 - 3.8e-49 166.2 30.8 4.4e-49 166.0 21.3 1.0 1 0 0 1 1 1 1 Tropomyosin like Tropomyosin PF00261.15 EXF74585.1 - 4.8e-09 35.6 30.8 4.9e-05 22.5 8.7 3.0 1 1 2 3 3 3 3 Tropomyosin Cast PF10174.4 EXF74585.1 - 0.0001 20.5 24.0 0.00012 20.3 16.7 1.1 1 0 0 1 1 1 1 RIM-binding protein of the cytomatrix active zone ATG16 PF08614.6 EXF74585.1 - 0.00015 21.6 26.0 0.0055 16.5 10.6 2.1 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 EXF74585.1 - 0.00017 21.4 29.4 0.00017 21.4 2.6 3.0 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 EXF74585.1 - 0.0002 19.2 29.0 0.00023 19.0 20.1 1.0 1 0 0 1 1 1 1 Myosin tail TMF_TATA_bd PF12325.3 EXF74585.1 - 0.00041 20.0 23.1 0.0018 17.9 9.4 2.3 1 1 1 2 2 2 1 TATA element modulatory factor 1 TATA binding Mod_r PF07200.8 EXF74585.1 - 0.00049 20.0 22.0 0.013 15.4 10.2 2.1 1 1 1 2 2 2 2 Modifier of rudimentary (Mod(r)) protein ADIP PF11559.3 EXF74585.1 - 0.0018 18.2 28.0 0.0036 17.2 5.1 3.1 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding GAS PF13851.1 EXF74585.1 - 0.0018 17.5 27.3 0.0043 16.2 18.9 1.7 1 1 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF4200 PF13863.1 EXF74585.1 - 0.0021 17.9 30.3 0.082 12.8 6.1 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4200) ERM PF00769.14 EXF74585.1 - 0.0024 17.4 32.8 0.016 14.7 10.0 2.2 1 1 1 2 2 2 2 Ezrin/radixin/moesin family Spc7 PF08317.6 EXF74585.1 - 0.0048 15.6 24.0 0.023 13.3 7.3 2.0 1 1 1 2 2 2 2 Spc7 kinetochore protein APG6 PF04111.7 EXF74585.1 - 0.007 15.4 30.9 0.083 11.9 10.0 2.0 1 1 1 2 2 2 2 Autophagy protein Apg6 bZIP_1 PF00170.16 EXF74585.1 - 0.011 15.6 29.1 0.37 10.7 1.8 4.9 2 1 2 4 4 3 0 bZIP transcription factor IncA PF04156.9 EXF74585.1 - 0.017 14.7 27.2 0.93 9.0 18.9 2.3 1 1 0 1 1 1 0 IncA protein FlaC_arch PF05377.6 EXF74585.1 - 0.019 14.8 16.5 0.99 9.3 2.2 4.3 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) Surfac_D-trimer PF09006.6 EXF74585.1 - 0.023 14.4 4.6 0.063 13.0 0.0 3.3 4 0 0 4 4 3 0 Lung surfactant protein D coiled-coil trimerisation Filament PF00038.16 EXF74585.1 - 0.033 13.6 24.2 0.11 11.8 16.8 1.7 1 1 0 1 1 1 0 Intermediate filament protein DUF3287 PF11690.3 EXF74585.1 - 0.036 14.1 7.3 0.034 14.2 1.8 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3287) TMF_DNA_bd PF12329.3 EXF74585.1 - 0.037 13.8 29.7 6.8 6.5 7.3 3.0 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Syntaxin-6_N PF09177.6 EXF74585.1 - 0.042 14.2 14.9 1 9.8 1.8 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Lebercilin PF15619.1 EXF74585.1 - 0.049 13.0 28.8 0.96 8.8 8.5 2.1 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease V_ATPase_I PF01496.14 EXF74585.1 - 0.054 11.3 14.7 0.064 11.1 10.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fib_alpha PF08702.5 EXF74585.1 - 0.059 13.4 15.1 0.86 9.7 2.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Cortex-I_coil PF09304.5 EXF74585.1 - 0.063 13.3 25.2 0.87 9.6 0.1 3.2 1 1 2 3 3 3 0 Cortexillin I, coiled coil BLOC1_2 PF10046.4 EXF74585.1 - 0.071 13.2 18.0 0.41 10.8 3.5 3.2 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Herpes_pp85 PF04637.7 EXF74585.1 - 0.076 11.2 2.4 0.067 11.4 0.8 1.5 1 1 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) EzrA PF06160.7 EXF74585.1 - 0.08 11.1 21.6 0.022 12.9 3.0 2.1 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA NPV_P10 PF05531.7 EXF74585.1 - 0.097 12.9 8.0 1.3 9.3 1.6 3.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein CCDC155 PF14662.1 EXF74585.1 - 0.12 11.9 30.9 0.52 9.8 7.6 2.1 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 PilJ PF13675.1 EXF74585.1 - 0.12 12.6 11.4 0.96 9.7 3.3 2.8 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Reo_sigmaC PF04582.7 EXF74585.1 - 0.13 11.4 2.5 4.2 6.4 1.1 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Fmp27_WPPW PF10359.4 EXF74585.1 - 0.13 10.6 20.4 0.038 12.4 4.8 2.0 1 1 1 2 2 2 0 RNA pol II promoter Fmp27 protein domain Seryl_tRNA_N PF02403.17 EXF74585.1 - 0.14 12.1 24.3 0.43 10.6 0.2 3.1 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.7 EXF74585.1 - 0.15 11.8 15.7 0.033 13.9 2.9 2.6 1 1 1 2 2 2 0 Laminin Domain II HAP1_N PF04849.8 EXF74585.1 - 0.16 10.8 25.4 0.37 9.6 17.6 2.0 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Atg14 PF10186.4 EXF74585.1 - 0.23 10.3 21.7 0.044 12.7 8.7 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF3166 PF11365.3 EXF74585.1 - 0.24 11.8 16.6 0.62 10.5 6.1 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF3166) Lge1 PF11488.3 EXF74585.1 - 0.24 11.5 18.6 0.28 11.4 2.9 3.0 1 1 1 2 2 2 0 Transcriptional regulatory protein LGE1 Nup54 PF13874.1 EXF74585.1 - 0.29 10.7 20.3 0.36 10.4 5.6 2.7 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 AAA_13 PF13166.1 EXF74585.1 - 0.32 9.4 21.1 0.74 8.1 4.5 1.9 1 1 0 1 1 1 0 AAA domain KLRAQ PF10205.4 EXF74585.1 - 0.35 10.9 18.1 0.14 12.2 4.4 2.8 1 1 2 3 3 3 0 Predicted coiled-coil domain-containing protein DUF869 PF05911.6 EXF74585.1 - 0.39 8.8 23.0 1.7 6.7 15.9 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) TBPIP PF07106.8 EXF74585.1 - 0.4 10.2 23.9 4 6.9 1.2 3.0 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Striatin PF08232.7 EXF74585.1 - 0.45 10.8 21.9 0.36 11.1 9.1 2.2 1 1 1 2 2 2 0 Striatin family HOOK PF05622.7 EXF74585.1 - 0.57 7.9 22.8 0.78 7.4 15.8 1.2 1 0 0 1 1 1 0 HOOK protein TPR_MLP1_2 PF07926.7 EXF74585.1 - 0.59 9.8 31.1 2.2 8.0 7.0 2.2 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Vps5 PF09325.5 EXF74585.1 - 0.63 9.2 21.4 0.029 13.6 6.5 2.6 1 1 2 3 3 3 0 Vps5 C terminal like MCPsignal PF00015.16 EXF74585.1 - 0.64 9.5 9.0 0.3 10.6 4.2 1.8 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3450 PF11932.3 EXF74585.1 - 0.64 9.2 22.0 0.83 8.8 6.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) WEMBL PF05701.6 EXF74585.1 - 0.65 8.3 28.4 1 7.7 15.8 2.1 1 1 1 2 2 2 0 Weak chloroplast movement under blue light Jnk-SapK_ap_N PF09744.4 EXF74585.1 - 0.66 9.9 23.0 0.74 9.7 8.1 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF1664 PF07889.7 EXF74585.1 - 0.66 9.7 12.4 3.8 7.3 2.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF4407 PF14362.1 EXF74585.1 - 0.67 8.8 20.8 1.2 8.0 14.4 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF904 PF06005.7 EXF74585.1 - 0.67 10.2 34.6 2.8 8.2 1.2 3.7 2 2 1 3 3 3 0 Protein of unknown function (DUF904) IFT46_B_C PF12317.3 EXF74585.1 - 0.82 8.9 6.1 0.22 10.8 1.4 1.8 1 1 1 2 2 2 0 Intraflagellar transport complex B protein 46 C terminal CDC37_N PF03234.9 EXF74585.1 - 1 9.6 21.1 5 7.3 14.6 2.2 1 1 0 1 1 1 0 Cdc37 N terminal kinase binding DUF4140 PF13600.1 EXF74585.1 - 1.2 9.6 20.4 2.2 8.7 1.8 3.2 1 1 1 2 2 1 0 N-terminal domain of unknown function (DUF4140) rRNA_proc-arch PF13234.1 EXF74585.1 - 1.6 7.8 12.5 0.25 10.4 2.7 2.4 1 1 1 2 2 2 0 rRNA-processing arch domain DUF972 PF06156.8 EXF74585.1 - 1.6 9.0 23.3 2.4 8.5 6.5 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF972) DUF3584 PF12128.3 EXF74585.1 - 1.7 5.8 25.2 0.48 7.6 11.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) MAD PF05557.8 EXF74585.1 - 1.7 6.6 25.2 1.1 7.3 8.9 2.0 1 1 0 1 1 1 0 Mitotic checkpoint protein WXG100 PF06013.7 EXF74585.1 - 1.8 8.5 14.9 6.3 6.8 0.2 4.1 2 1 1 3 3 3 0 Proteins of 100 residues with WXG Methyltransf_9 PF08003.6 EXF74585.1 - 2.4 6.7 6.8 3.7 6.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) DUF4201 PF13870.1 EXF74585.1 - 2.5 7.4 22.3 36 3.7 15.5 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) FliD_N PF02465.13 EXF74585.1 - 2.5 8.4 11.4 3.7 7.9 0.2 3.3 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Mnd1 PF03962.10 EXF74585.1 - 2.6 7.6 27.9 5 6.7 6.2 2.1 1 1 1 2 2 2 0 Mnd1 family DUF745 PF05335.8 EXF74585.1 - 2.8 7.4 18.6 0.17 11.3 3.2 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF745) DUF724 PF05266.9 EXF74585.1 - 3.4 7.2 24.9 1.5 8.3 6.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Sec5 PF15469.1 EXF74585.1 - 3.5 7.3 11.4 1.5 8.5 0.4 2.4 1 1 1 2 2 2 0 Exocyst complex component Sec5 Med14 PF08638.6 EXF74585.1 - 3.6 6.7 6.6 17 4.6 0.7 2.7 1 1 1 2 2 2 0 Mediator complex subunit MED14 Phage_GP20 PF06810.6 EXF74585.1 - 3.9 6.9 25.6 3.7 6.9 7.4 2.5 1 1 1 2 2 2 0 Phage minor structural protein GP20 DUF2730 PF10805.3 EXF74585.1 - 4.7 6.9 14.8 0.28 10.9 3.1 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) HSP70 PF00012.15 EXF74585.1 - 5.1 4.8 16.5 6.7 4.4 11.4 1.3 1 0 0 1 1 1 0 Hsp70 protein Uds1 PF15456.1 EXF74585.1 - 5.9 6.9 21.7 8.9 6.3 2.2 2.5 1 1 0 2 2 2 0 Up-regulated During Septation SlyX PF04102.7 EXF74585.1 - 5.9 7.3 19.6 13 6.1 1.6 3.6 2 2 1 3 3 3 0 SlyX Cep57_MT_bd PF06657.8 EXF74585.1 - 6.7 6.7 16.1 0.94 9.4 1.6 3.4 1 1 3 4 4 3 0 Centrosome microtubule-binding domain of Cep57 Shugoshin_N PF07558.6 EXF74585.1 - 7.1 6.4 9.7 1.4 8.6 1.8 3.4 3 1 0 4 4 2 0 Shugoshin N-terminal coiled-coil region FliJ PF02050.11 EXF74585.1 - 8.1 6.5 26.1 26 4.8 10.1 2.5 1 1 1 2 2 2 0 Flagellar FliJ protein DUF2937 PF11157.3 EXF74585.1 - 9.2 5.5 8.3 8.9 5.6 3.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) N-SET PF11764.3 EXF74587.1 - 1.6e-35 122.4 0.4 1.6e-35 122.4 0.3 2.4 2 0 0 2 2 2 1 COMPASS (Complex proteins associated with Set1p) component N SET_assoc PF11767.3 EXF74587.1 - 5.2e-22 76.9 1.4 6.7e-22 76.5 0.2 1.8 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated SET PF00856.23 EXF74587.1 - 6.2e-22 78.6 0.1 6.2e-22 78.6 0.1 3.6 4 2 0 4 4 4 1 SET domain RRM_1 PF00076.17 EXF74587.1 - 0.0076 15.8 0.1 0.98 9.0 0.0 2.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF74587.1 - 0.1 12.4 0.1 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cupin_8 PF13621.1 EXF74588.1 - 9.1e-68 228.4 0.1 1.2e-67 228.1 0.1 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EXF74588.1 - 1.2e-06 28.0 0.0 0.00032 20.0 0.1 2.3 2 0 0 2 2 2 2 Cupin superfamily protein JmjC PF02373.17 EXF74588.1 - 0.057 13.6 0.1 0.46 10.7 0.0 2.5 2 1 1 3 3 3 0 JmjC domain, hydroxylase Sterol-sensing PF12349.3 EXF74589.1 - 1.2e-37 128.7 9.7 2.1e-37 127.9 6.7 1.4 1 0 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EXF74589.1 - 7.6e-11 40.6 7.9 1.1e-10 40.1 5.5 1.1 1 0 0 1 1 1 1 Patched family WD40 PF00400.27 EXF74589.1 - 0.12 12.2 2.4 0.24 11.3 0.1 2.7 3 0 0 3 3 3 0 WD domain, G-beta repeat Imm16 PF15565.1 EXF74590.1 - 0.036 13.9 0.1 0.073 12.9 0.1 1.5 1 0 0 1 1 1 0 Immunity protein 16 Tyr-DNA_phospho PF06087.7 EXF74590.1 - 0.075 11.6 0.1 0.098 11.2 0.0 1.1 1 0 0 1 1 1 0 Tyrosyl-DNA phosphodiesterase Retinal PF15449.1 EXF74590.1 - 0.56 7.8 12.4 0.62 7.6 8.6 1.0 1 0 0 1 1 1 0 Retinal protein DUF2296 PF10058.4 EXF74591.1 - 2.1e-20 72.2 0.3 6.7e-20 70.5 0.1 1.9 2 0 0 2 2 2 1 Predicted integral membrane metal-binding protein (DUF2296) PAT1 PF09770.4 EXF74591.1 - 2 6.5 11.8 2.7 6.1 8.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GRIP PF01465.15 EXF74592.1 - 3.5e-15 55.2 0.1 8.2e-15 54.0 0.0 1.7 1 0 0 1 1 1 1 GRIP domain CENP-F_leu_zip PF10473.4 EXF74592.1 - 1.4e-07 31.4 181.1 0.002 17.9 19.2 9.3 3 2 7 10 10 9 7 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EXF74592.1 - 1.2e-05 24.9 162.3 0.033 13.7 12.3 8.7 3 2 4 7 7 6 4 IncA protein MAD PF05557.8 EXF74592.1 - 6e-05 21.3 28.4 6e-05 21.3 19.7 6.1 3 1 4 7 7 6 1 Mitotic checkpoint protein Phage_GP20 PF06810.6 EXF74592.1 - 0.00028 20.3 6.5 0.00028 20.3 4.5 11.8 3 2 8 11 11 11 3 Phage minor structural protein GP20 DUF3584 PF12128.3 EXF74592.1 - 0.00043 17.7 27.2 0.00043 17.7 18.9 5.5 3 1 2 5 5 5 2 Protein of unknown function (DUF3584) AAA_13 PF13166.1 EXF74592.1 - 0.001 17.6 133.8 0.0013 17.3 20.2 5.7 3 2 2 5 5 5 3 AAA domain GAS PF13851.1 EXF74592.1 - 0.0015 17.8 167.0 0.0083 15.3 8.6 9.7 3 3 6 9 9 9 5 Growth-arrest specific micro-tubule binding Reo_sigmaC PF04582.7 EXF74592.1 - 0.002 17.3 53.1 0.055 12.6 3.0 7.0 3 2 2 7 7 7 6 Reovirus sigma C capsid protein Filament PF00038.16 EXF74592.1 - 0.0024 17.4 148.2 0.23 10.8 13.3 10.3 3 2 5 8 8 7 4 Intermediate filament protein Laminin_I PF06008.9 EXF74592.1 - 0.004 16.4 10.4 0.004 16.4 7.2 6.2 3 2 2 5 5 3 1 Laminin Domain I HOOK PF05622.7 EXF74592.1 - 0.018 12.8 142.0 0.0089 13.8 0.7 4.5 3 1 1 4 4 4 0 HOOK protein Myosin_tail_1 PF01576.14 EXF74592.1 - 0.076 10.7 182.0 0.071 10.8 12.2 6.5 3 2 1 5 5 5 0 Myosin tail NPV_P10 PF05531.7 EXF74592.1 - 0.16 12.2 71.2 0.82 9.9 1.0 10.9 8 2 2 10 10 10 0 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.2 EXF74592.1 - 0.27 10.5 141.6 0.011 15.1 16.4 7.3 4 1 4 8 8 8 0 Mechanosensitive ion channel porin domain TPR_MLP1_2 PF07926.7 EXF74592.1 - 2.9 7.6 160.5 0.37 10.5 8.5 9.7 3 2 4 8 8 8 0 TPR/MLP1/MLP2-like protein adh_short PF00106.20 EXF74593.1 - 4.3e-23 82.0 0.6 4.7e-22 78.6 0.4 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF74593.1 - 5e-20 72.2 1.9 9.7e-20 71.3 1.4 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF74593.1 - 1.1e-07 31.6 0.7 7e-07 29.0 0.5 2.1 1 1 0 1 1 1 1 KR domain NAD_binding_7 PF13241.1 EXF74593.1 - 0.00094 19.4 0.2 0.0037 17.4 0.1 2.0 1 1 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EXF74593.1 - 0.0028 17.7 0.3 0.0088 16.1 0.2 1.9 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EXF74593.1 - 0.0058 16.6 0.3 0.016 15.1 0.1 1.9 2 1 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EXF74593.1 - 0.0089 15.4 0.4 0.045 13.1 0.2 2.1 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 EXF74593.1 - 0.021 14.3 0.0 0.047 13.2 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase F420_oxidored PF03807.12 EXF74593.1 - 0.04 14.3 0.1 0.094 13.1 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AdoHcyase_NAD PF00670.16 EXF74593.1 - 0.14 12.0 0.9 0.26 11.0 0.6 1.5 1 1 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain bZIP_1 PF00170.16 EXF74594.1 - 0.0053 16.6 4.5 0.011 15.6 3.2 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EXF74594.1 - 0.16 11.7 5.8 0.49 10.2 4.0 1.8 1 1 0 1 1 1 0 Basic region leucine zipper Methyltransf_23 PF13489.1 EXF74595.1 - 2.9e-20 72.5 0.0 4.4e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF74595.1 - 1.3e-12 48.2 0.0 3.5e-11 43.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF74595.1 - 3.9e-11 42.7 0.0 8.4e-10 38.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF74595.1 - 2.4e-07 31.1 0.0 5e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF74595.1 - 5.8e-07 29.9 0.0 6.1e-06 26.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF74595.1 - 0.00055 19.3 0.0 0.02 14.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EXF74595.1 - 0.00084 19.3 0.0 0.0051 16.8 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF74595.1 - 0.0039 17.5 0.0 0.016 15.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF74595.1 - 0.0054 15.8 0.0 0.013 14.5 0.0 1.6 2 0 0 2 2 2 1 Putative methyltransferase CheR PF01739.13 EXF74595.1 - 0.008 15.4 0.0 0.013 14.7 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain FtsJ PF01728.14 EXF74595.1 - 0.0081 16.1 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EXF74595.1 - 0.038 13.4 0.0 0.058 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 EXF74595.1 - 0.071 12.2 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EXF74595.1 - 0.11 11.6 0.0 6.8 5.7 0.0 2.3 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family TGS PF02824.16 EXF74595.1 - 0.13 12.0 0.0 22 5.0 0.0 2.3 2 0 0 2 2 2 0 TGS domain DisA_N PF02457.11 EXF74596.1 - 0.13 11.4 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 DisA bacterial checkpoint controller nucleotide-binding FAD_binding_3 PF01494.14 EXF74597.1 - 3e-74 250.2 0.0 3.6e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF74597.1 - 4.7e-06 25.7 0.0 0.0039 16.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF74597.1 - 0.0077 15.1 0.3 0.029 13.2 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EXF74597.1 - 0.018 15.0 0.0 0.054 13.5 0.0 1.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EXF74597.1 - 0.022 13.8 0.0 0.036 13.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family HI0933_like PF03486.9 EXF74597.1 - 0.061 11.7 0.0 0.12 10.7 0.0 1.5 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_2 PF07992.9 EXF74597.1 - 0.065 13.1 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF74597.1 - 0.11 12.5 0.0 0.83 9.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EXF74597.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain Sugar_tr PF00083.19 EXF74598.1 - 9.7e-71 238.6 21.3 7.8e-47 159.8 3.4 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EXF74598.1 - 3.4e-10 39.1 23.3 1.1e-09 37.4 16.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MPC PF03650.8 EXF74600.1 - 1.7e-41 140.9 0.9 2.3e-41 140.4 0.3 1.5 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0041) YqjK PF13997.1 EXF74600.1 - 0.64 10.2 3.4 1.8 8.8 1.6 2.3 2 1 0 2 2 2 0 YqjK-like protein L51_S25_CI-B8 PF05047.11 EXF74601.1 - 4.3e-12 45.5 0.0 7.7e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF1687 PF07955.6 EXF74603.1 - 9e-19 67.7 0.8 6.2e-18 65.0 0.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1687) CBP PF12192.3 EXF74603.1 - 0.0095 15.8 0.3 0.87 9.5 0.0 2.3 2 0 0 2 2 2 1 Fungal calcium binding protein ArsC PF03960.10 EXF74603.1 - 0.014 15.4 0.0 0.48 10.5 0.0 2.2 1 1 0 1 1 1 0 ArsC family FMN_dh PF01070.13 EXF74603.1 - 0.027 13.3 0.2 0.034 12.9 0.1 1.1 1 0 0 1 1 1 0 FMN-dependent dehydrogenase Ribosomal_L14e PF01929.12 EXF74605.1 - 1.1e-24 86.5 2.8 1.4e-24 86.1 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.24 EXF74605.1 - 5.8e-05 22.6 0.5 0.00029 20.4 0.0 2.4 3 0 0 3 3 3 1 KOW motif NAC PF01849.13 EXF74606.1 - 1.1e-25 88.8 0.2 1.8e-24 85.0 0.0 2.3 2 0 0 2 2 2 1 NAC domain UBA PF00627.26 EXF74606.1 - 0.001 18.8 2.1 0.0011 18.7 0.1 2.1 2 0 0 2 2 2 1 UBA/TS-N domain DUF3394 PF11874.3 EXF74606.1 - 0.071 12.6 2.1 0.067 12.7 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3394) Ribosomal_S13 PF00416.17 EXF74606.1 - 0.12 12.8 0.8 0.64 10.5 0.2 2.1 2 0 0 2 2 2 0 Ribosomal protein S13/S18 Pox_RNA_Pol_19 PF05320.7 EXF74606.1 - 1.3 8.7 10.3 2.7 7.7 0.1 2.2 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit CENP-B_dimeris PF09026.5 EXF74606.1 - 3.4 7.9 11.7 7.5 6.8 0.2 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain HNF-1_N PF04814.8 EXF74606.1 - 3.9 7.5 6.4 0.46 10.5 1.3 1.7 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Myc_N PF01056.13 EXF74606.1 - 6.9 5.7 11.8 0.13 11.4 2.4 1.9 2 0 0 2 2 2 0 Myc amino-terminal region Protamine_P2 PF00841.14 EXF74606.1 - 9.4 6.8 6.1 2.6 8.6 0.1 2.4 2 1 1 3 3 3 0 Sperm histone P2 Mt_ATP-synt_D PF05873.7 EXF74607.1 - 5.5e-19 68.3 1.2 6.7e-19 68.0 0.8 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) T5orf172 PF10544.4 EXF74607.1 - 0.16 12.4 0.3 0.5 10.7 0.2 1.8 1 1 0 1 1 1 0 T5orf172 domain BLOC1_2 PF10046.4 EXF74607.1 - 0.29 11.3 4.7 2.2 8.4 1.4 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Abhydrolase_3 PF07859.8 EXF74608.1 - 1.7e-33 115.9 0.1 2.7e-33 115.3 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EXF74608.1 - 6.8e-08 32.6 5.0 4.7e-07 29.9 3.5 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF74608.1 - 0.00069 19.3 0.1 0.0011 18.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF74608.1 - 0.026 14.1 0.0 0.14 11.7 0.0 1.9 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EXF74608.1 - 0.042 13.0 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family MFS_1 PF07690.11 EXF74611.1 - 1e-36 126.4 24.1 1e-36 126.4 16.7 2.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF74611.1 - 1.8e-11 43.3 14.6 1.8e-11 43.3 10.1 2.8 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EXF74611.1 - 0.00064 18.0 2.5 0.00064 18.0 1.8 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Thioredoxin PF00085.15 EXF74612.1 - 4.4e-07 29.5 0.0 6.7e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 EXF74612.1 - 0.0019 17.7 0.0 0.017 14.6 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin Redoxin PF08534.5 EXF74612.1 - 0.013 15.0 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Redoxin DUF953 PF06110.6 EXF74612.1 - 0.026 13.9 0.4 0.24 10.8 0.3 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_2 PF13098.1 EXF74612.1 - 0.065 13.4 0.0 1.3 9.2 0.0 2.1 1 1 0 1 1 1 0 Thioredoxin-like domain DUF718 PF05336.8 EXF74613.1 - 2.8e-34 117.0 0.7 3.3e-34 116.8 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF718) Amidohydro_2 PF04909.9 EXF74614.1 - 2.1e-42 145.6 2.3 2.6e-42 145.3 1.6 1.1 1 0 0 1 1 1 1 Amidohydrolase zf-RING_2 PF13639.1 EXF74616.1 - 1.3e-13 50.5 5.6 2e-13 49.8 3.9 1.3 1 0 0 1 1 1 1 Ring finger domain PA PF02225.17 EXF74616.1 - 1.8e-12 46.8 0.0 4.6e-12 45.5 0.0 1.7 1 0 0 1 1 1 1 PA domain zf-C3HC4_2 PF13923.1 EXF74616.1 - 2e-09 37.2 5.2 3.3e-09 36.6 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EXF74616.1 - 6.9e-09 35.6 2.3 1.3e-08 34.8 1.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EXF74616.1 - 1.1e-08 34.6 3.1 1.7e-08 33.9 2.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EXF74616.1 - 5.9e-08 32.2 3.2 8.9e-08 31.6 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EXF74616.1 - 2.7e-07 30.1 2.4 4.2e-07 29.5 1.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EXF74616.1 - 0.0011 18.7 1.0 0.002 17.8 0.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EXF74616.1 - 0.052 13.4 3.8 0.21 11.5 2.8 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EXF74616.1 - 0.084 12.8 2.4 0.21 11.5 1.6 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain RINGv PF12906.2 EXF74616.1 - 0.097 12.7 3.7 0.18 11.8 2.6 1.5 1 0 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 EXF74616.1 - 0.11 12.2 2.6 0.24 11.1 1.8 1.6 1 0 0 1 1 1 0 RING-type zinc-finger Baculo_RING PF05883.6 EXF74616.1 - 0.14 11.9 0.1 0.24 11.2 0.1 1.2 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_4 PF14570.1 EXF74616.1 - 0.91 9.1 2.5 1.7 8.2 1.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EXF74616.1 - 1.7 8.6 3.4 3.1 7.8 2.4 1.4 1 0 0 1 1 1 0 RING-like domain Y_phosphatase PF00102.22 EXF74617.1 - 5.8e-48 163.2 0.0 1.4e-47 162.0 0.0 1.6 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EXF74617.1 - 0.0044 17.0 0.0 0.0092 16.0 0.0 1.5 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.15 EXF74617.1 - 0.0096 15.5 0.0 0.02 14.4 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EXF74617.1 - 0.034 14.4 0.0 0.061 13.5 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family RCC1 PF00415.13 EXF74618.1 - 8e-31 106.0 4.5 7.5e-09 35.6 0.0 8.1 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EXF74618.1 - 4.9e-16 57.8 23.7 8e-10 38.0 0.0 7.3 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat Sec34 PF04136.10 EXF74619.1 - 2.8e-30 105.0 0.7 2.8e-30 105.0 0.5 2.0 2 0 0 2 2 2 1 Sec34-like family Pkinase PF00069.20 EXF74620.1 - 6.1e-23 81.2 0.0 1.9e-22 79.6 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF74620.1 - 8.5e-15 54.5 0.0 2e-13 50.0 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase COQ7 PF03232.8 EXF74621.1 - 0.061 12.7 0.1 0.092 12.2 0.0 1.2 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 ATG16 PF08614.6 EXF74622.1 - 1.5e-05 24.8 2.5 2.9e-05 24.0 1.8 1.4 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DivIC PF04977.10 EXF74622.1 - 0.00053 19.4 3.3 0.0016 17.9 2.3 1.7 1 0 0 1 1 1 1 Septum formation initiator ADIP PF11559.3 EXF74622.1 - 0.001 19.0 2.9 0.0019 18.1 2.0 1.4 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding NTR2 PF15458.1 EXF74622.1 - 0.0059 15.8 2.0 0.011 14.9 1.4 1.4 1 0 0 1 1 1 1 Nineteen complex-related protein 2 V_ATPase_I PF01496.14 EXF74622.1 - 0.031 12.1 1.4 0.039 11.8 1.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_1 PF00170.16 EXF74622.1 - 0.032 14.2 2.2 0.079 12.9 0.6 2.1 1 1 1 2 2 2 0 bZIP transcription factor IncA PF04156.9 EXF74622.1 - 0.039 13.5 5.6 0.063 12.8 3.9 1.3 1 0 0 1 1 1 0 IncA protein Mnd1 PF03962.10 EXF74622.1 - 0.052 13.2 2.4 0.078 12.6 1.7 1.2 1 0 0 1 1 1 0 Mnd1 family FlaC_arch PF05377.6 EXF74622.1 - 0.059 13.2 1.4 0.15 11.9 1.0 1.6 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) APG6 PF04111.7 EXF74622.1 - 0.33 9.9 4.4 0.52 9.3 3.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Tropomyosin_1 PF12718.2 EXF74622.1 - 0.5 10.1 8.1 0.35 10.7 2.8 2.2 1 1 1 2 2 2 0 Tropomyosin like TMF_DNA_bd PF12329.3 EXF74622.1 - 0.89 9.4 6.9 1.3 8.9 4.1 1.7 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Spc24 PF08286.6 EXF74622.1 - 2.4 7.8 8.0 4.1 7.1 4.9 1.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 SlyX PF04102.7 EXF74622.1 - 7.6 6.9 8.9 11 6.5 4.5 2.4 1 1 1 2 2 2 0 SlyX Alpha_L_fucos PF01120.12 EXF74623.1 - 1.1e-28 100.1 0.2 2.2e-28 99.1 0.2 1.5 1 1 0 1 1 1 1 Alpha-L-fucosidase F5_F8_type_C PF00754.20 EXF74623.1 - 2e-09 37.3 1.1 5.9e-09 35.8 0.0 2.3 2 1 1 3 3 3 1 F5/8 type C domain SGL PF08450.7 EXF74624.1 - 2.8e-23 82.5 0.4 7.4e-23 81.1 0.2 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EXF74624.1 - 0.00078 19.4 0.0 0.0044 17.0 0.0 2.1 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 EXF74624.1 - 0.033 14.1 0.0 0.21 11.6 0.0 2.3 1 1 1 2 2 2 0 Arylesterase Glyco_hydro_43 PF04616.9 EXF74626.1 - 5.6e-22 78.1 0.4 1.1e-16 60.7 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 CFEM PF05730.6 EXF74628.1 - 1.5e-10 40.7 8.2 3.2e-10 39.6 5.7 1.5 1 0 0 1 1 1 1 CFEM domain DUF1673 PF07895.6 EXF74628.1 - 0.82 9.1 8.0 0.15 11.5 2.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Sugar_tr PF00083.19 EXF74629.1 - 5.4e-92 308.7 21.3 5.4e-92 308.7 14.7 1.5 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF74629.1 - 7.4e-22 77.5 27.4 3.7e-20 71.9 5.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 EXF74630.1 - 6.1e-25 88.0 1.2 1e-24 87.3 0.9 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF74630.1 - 2.5e-12 47.1 0.0 3.8e-12 46.5 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF74630.1 - 7.9e-08 32.1 0.8 3.3e-07 30.1 0.4 1.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 EXF74630.1 - 1.7e-05 24.3 0.0 3.3e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF74630.1 - 0.00049 20.1 2.5 0.013 15.4 0.8 2.5 1 1 0 1 1 1 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EXF74630.1 - 0.0034 17.1 0.4 0.0091 15.7 0.3 1.8 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.10 EXF74630.1 - 0.01 14.7 0.0 0.015 14.2 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EXF74630.1 - 0.011 15.4 0.0 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ldh_1_N PF00056.18 EXF74630.1 - 0.018 14.8 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain NmrA PF05368.8 EXF74630.1 - 0.022 14.0 0.0 0.12 11.6 0.0 2.1 3 0 0 3 3 3 0 NmrA-like family THF_DHG_CYH_C PF02882.14 EXF74630.1 - 0.085 11.9 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.11 EXF74630.1 - 0.099 12.0 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Fungal_trans PF04082.13 EXF74631.1 - 0.0093 14.8 0.0 0.021 13.7 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain CAP_N PF01213.14 EXF74631.1 - 6.3 5.9 8.7 13 5.0 6.0 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TMEM247 PF15444.1 EXF74632.1 - 0.034 13.9 0.6 0.043 13.6 0.4 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 FAD_binding_1 PF00667.15 EXF74634.1 - 5.4e-43 146.9 0.0 8.6e-43 146.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EXF74634.1 - 1.9e-09 38.0 0.0 4.5e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain T2SG PF08334.6 EXF74634.1 - 0.18 11.6 2.0 12 5.6 0.1 2.7 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein G Nitroreductase PF00881.19 EXF74635.1 - 5.6e-14 52.2 0.0 6.8e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family DUF1983 PF09327.6 EXF74635.1 - 0.012 15.5 0.1 0.63 10.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1983) PS_Dcarbxylase PF02666.10 EXF74636.1 - 2.9e-80 268.3 0.0 1.4e-79 266.0 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl PF00364.17 EXF74636.1 - 0.065 12.8 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 Biotin-requiring enzyme ubiquitin PF00240.18 EXF74637.1 - 7.2e-08 31.7 0.1 1.9e-07 30.3 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EXF74637.1 - 4.8e-05 23.4 0.4 0.00014 21.9 0.0 2.0 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.3 EXF74637.1 - 0.017 14.8 0.0 0.047 13.3 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Raftlin PF15250.1 EXF74637.1 - 0.61 8.5 5.8 0.1 11.1 1.2 1.7 2 0 0 2 2 2 0 Raftlin zf-CCCH_2 PF14608.1 EXF74638.1 - 0.024 14.6 6.5 0.024 14.6 4.5 2.6 2 1 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type SPRY PF00622.23 EXF74639.1 - 8.6e-20 71.0 0.0 1.4e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 SPRY domain adh_short PF00106.20 EXF74641.1 - 3.8e-14 52.9 3.8 8.7e-11 42.0 0.0 2.4 1 1 1 2 2 2 2 short chain dehydrogenase 3HCDH_N PF02737.13 EXF74641.1 - 0.012 15.2 0.1 0.068 12.8 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EXF74641.1 - 0.066 13.0 0.2 0.066 13.0 0.2 1.6 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase CobA_CobO_BtuR PF02572.10 EXF74641.1 - 0.16 11.5 0.1 8.2 6.0 0.0 2.6 3 0 0 3 3 3 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP GFA PF04828.9 EXF74642.1 - 7.9e-20 70.6 0.7 1.2e-19 70.0 0.5 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme FAD_binding_3 PF01494.14 EXF74643.1 - 7.4e-32 110.7 0.0 2.3e-31 109.1 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF74643.1 - 1.3e-09 37.4 0.7 0.00024 20.1 0.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EXF74643.1 - 3e-09 36.4 0.0 0.00055 19.1 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EXF74643.1 - 1.3e-06 28.3 0.2 4.6e-06 26.5 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EXF74643.1 - 4.4e-06 26.0 0.1 1.9e-05 23.9 0.0 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EXF74643.1 - 1.5e-05 24.2 0.2 7.4e-05 21.9 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 EXF74643.1 - 3.2e-05 24.2 0.8 0.00032 21.0 0.3 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF74643.1 - 9.2e-05 21.0 0.1 0.001 17.6 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EXF74643.1 - 0.00012 22.2 0.1 0.00028 21.0 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EXF74643.1 - 0.00026 19.7 0.1 0.00048 18.8 0.1 1.4 1 0 0 1 1 1 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EXF74643.1 - 0.00041 19.3 0.1 0.52 9.1 0.1 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EXF74643.1 - 0.00098 19.0 0.3 0.0016 18.3 0.2 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF74643.1 - 0.0011 17.9 0.2 0.0017 17.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.16 EXF74643.1 - 0.0024 17.4 0.1 0.0045 16.5 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 EXF74643.1 - 0.0059 15.5 0.2 0.011 14.6 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A TrkA_N PF02254.13 EXF74643.1 - 0.16 12.0 0.1 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain ScdA_N PF04405.9 EXF74643.1 - 0.17 11.3 0.1 11 5.5 0.0 2.8 3 0 0 3 3 3 0 Domain of Unknown function (DUF542) CrtC PF07143.6 EXF74644.1 - 9.5e-17 61.2 3.4 1.6e-16 60.4 2.4 1.3 1 1 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) Methyltransf_23 PF13489.1 EXF74645.1 - 1.6e-23 83.2 0.0 2.6e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF74645.1 - 4.9e-09 36.7 0.0 2.1e-08 34.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF74645.1 - 2.5e-08 34.2 0.0 4.2e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF74645.1 - 7.3e-08 32.1 0.0 4.2e-07 29.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF74645.1 - 2.2e-06 28.0 0.0 1e-05 25.8 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF74645.1 - 1.3e-05 25.5 0.0 2.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF74645.1 - 0.0029 16.6 0.0 0.0058 15.6 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EXF74645.1 - 0.039 13.3 0.0 0.11 11.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 EXF74645.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_17 PF12692.2 EXF74645.1 - 0.1 12.2 0.0 16 5.1 0.0 2.2 2 0 0 2 2 2 0 S-adenosyl-L-methionine methyltransferase Methyltransf_26 PF13659.1 EXF74645.1 - 0.11 12.5 0.0 0.53 10.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.15 EXF74645.1 - 0.11 11.5 0.0 0.32 10.0 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Zn_clus PF00172.13 EXF74649.1 - 5.6e-08 32.5 11.1 8.9e-08 31.9 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF74649.1 - 4.2e-07 28.9 0.3 8e-07 27.9 0.2 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain DUF4452 PF14618.1 EXF74650.1 - 7.6e-81 269.7 10.5 9.3e-81 269.4 7.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4452) Abhydrolase_6 PF12697.2 EXF74653.1 - 1.8e-20 73.8 4.1 3.6e-20 72.8 2.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF74653.1 - 7.8e-10 38.6 0.0 4.4e-09 36.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF74653.1 - 9.7e-08 31.8 0.5 5.1e-07 29.4 0.5 2.0 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EXF74653.1 - 7.1e-05 22.5 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Thioesterase PF00975.15 EXF74653.1 - 0.19 11.9 0.7 0.41 10.8 0.5 1.5 1 0 0 1 1 1 0 Thioesterase domain TauD PF02668.11 EXF74654.1 - 1.1e-28 100.6 0.0 2e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ank_2 PF12796.2 EXF74654.1 - 2.6e-20 72.5 1.7 6.1e-08 32.8 0.2 4.4 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EXF74654.1 - 1.7e-18 66.5 1.5 5.9e-09 36.2 0.1 5.0 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF74654.1 - 9e-18 63.9 3.1 2.6e-05 24.3 0.0 5.3 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF74654.1 - 1.2e-16 59.0 2.2 0.016 15.4 0.0 7.0 7 0 0 7 7 7 4 Ankyrin repeat Ank PF00023.25 EXF74654.1 - 1.7e-15 55.9 8.1 0.001 18.7 0.0 6.8 6 0 0 6 6 6 4 Ankyrin repeat MFS_1 PF07690.11 EXF74655.1 - 1.5e-28 99.5 35.5 1.5e-28 99.5 24.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily ATP_transf PF09830.4 EXF74657.1 - 8.5e-12 44.6 0.0 1.3e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 ATP adenylyltransferase Hydantoinase_B PF02538.9 EXF74658.1 - 2.9e-170 566.9 0.0 3.9e-170 566.5 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EXF74658.1 - 2.4e-91 305.8 0.1 4.2e-91 305.0 0.1 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EXF74658.1 - 3.1e-58 196.1 0.0 8.9e-57 191.4 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.11 EXF74659.1 - 3.3e-23 81.9 29.4 3.3e-23 81.9 20.4 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1049 PF06305.6 EXF74659.1 - 0.14 11.6 2.6 2.8 7.5 0.0 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) DAO PF01266.19 EXF74660.1 - 4.7e-55 186.9 0.1 6.8e-55 186.4 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EXF74660.1 - 1.7e-09 38.0 0.0 6.8e-05 23.0 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF74660.1 - 3.2e-07 30.2 0.0 9.1e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EXF74660.1 - 1.1e-06 28.9 0.5 0.094 13.1 0.0 3.1 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF74660.1 - 6.2e-06 26.2 0.0 0.01 15.7 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF74660.1 - 1.5e-05 24.0 2.1 0.00021 20.2 1.5 2.1 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EXF74660.1 - 1.6e-05 23.6 0.7 0.014 13.8 0.1 2.3 2 0 0 2 2 2 2 HI0933-like protein GIDA PF01134.17 EXF74660.1 - 0.00012 21.1 0.5 0.31 9.8 0.0 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A Thi4 PF01946.12 EXF74660.1 - 0.00014 21.0 0.0 0.00026 20.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Amino_oxidase PF01593.19 EXF74660.1 - 0.00019 20.6 0.0 0.53 9.2 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase ThiF PF00899.16 EXF74660.1 - 0.00053 19.8 0.1 0.0028 17.4 0.0 2.2 3 0 0 3 3 3 1 ThiF family Shikimate_DH PF01488.15 EXF74660.1 - 0.0027 17.8 0.0 0.0058 16.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EXF74660.1 - 0.0043 16.1 2.2 0.0065 15.5 0.1 2.4 3 1 0 3 3 3 1 FAD binding domain NAD_binding_9 PF13454.1 EXF74660.1 - 0.012 15.4 0.4 2.7 7.7 0.0 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding Cupin_1 PF00190.17 EXF74661.1 - 6.8e-10 38.5 0.3 1.1e-09 37.8 0.2 1.3 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EXF74661.1 - 0.028 13.9 0.0 0.056 12.9 0.0 1.5 1 0 0 1 1 1 0 Cupin domain GMC_oxred_N PF00732.14 EXF74662.1 - 4.7e-53 180.2 0.0 6.1e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF74662.1 - 1.2e-30 106.6 0.0 4.5e-30 104.8 0.0 1.9 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EXF74662.1 - 2.4e-07 30.0 0.1 0.0099 14.8 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF74662.1 - 0.00015 20.8 0.1 0.00043 19.3 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EXF74662.1 - 0.00038 19.4 1.0 0.17 10.7 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.17 EXF74662.1 - 0.00043 19.2 0.1 0.45 9.3 0.0 2.1 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EXF74662.1 - 0.0034 17.4 0.0 2.2 8.2 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF74662.1 - 0.013 15.3 0.0 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF74662.1 - 0.024 14.6 0.1 0.067 13.2 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EXF74662.1 - 0.063 11.7 0.3 1 7.7 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 EXF74662.1 - 0.13 12.0 0.4 12 5.6 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding MFS_1 PF07690.11 EXF74663.1 - 8.7e-26 90.4 28.9 1.1e-25 90.1 17.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DAO PF01266.19 EXF74664.1 - 2.8e-48 164.6 0.0 3.2e-48 164.4 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF74664.1 - 5.8e-07 29.4 0.0 1.5e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EXF74664.1 - 0.001 18.0 0.1 0.013 14.3 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.15 EXF74664.1 - 0.0012 18.9 0.0 0.0065 16.5 0.0 2.0 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EXF74664.1 - 0.0018 17.3 0.0 0.0026 16.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EXF74664.1 - 0.002 18.4 0.0 0.0082 16.5 0.0 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF74664.1 - 0.0097 15.9 0.0 0.019 15.0 0.0 1.5 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EXF74664.1 - 0.018 15.0 0.0 0.065 13.2 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_2 PF07992.9 EXF74664.1 - 0.023 14.5 0.0 0.076 12.8 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF74664.1 - 0.035 12.9 0.0 6.1 5.5 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EXF74664.1 - 0.053 12.1 0.1 6.2 5.3 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase ApbA PF02558.11 EXF74664.1 - 0.069 12.5 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_9 PF13454.1 EXF74664.1 - 0.088 12.5 0.0 0.53 10.0 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding GMC_oxred_N PF00732.14 EXF74664.1 - 0.12 11.5 0.0 0.29 10.2 0.0 1.6 2 0 0 2 2 2 0 GMC oxidoreductase NAD_binding_7 PF13241.1 EXF74664.1 - 0.14 12.3 0.0 0.29 11.4 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Fungal_trans PF04082.13 EXF74665.1 - 3.5e-11 42.4 0.0 7.6e-11 41.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF74665.1 - 0.038 13.9 1.9 0.085 12.7 1.3 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fructosamin_kin PF03881.9 EXF74666.1 - 2.9e-34 118.3 0.0 3.7e-34 118.0 0.0 1.1 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EXF74666.1 - 0.015 15.0 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family LtrA PF06772.6 EXF74667.1 - 4.2e-12 45.6 14.1 4.2e-12 45.6 9.8 2.7 2 1 0 2 2 2 1 Bacterial low temperature requirement A protein (LtrA) MFS_1 PF07690.11 EXF74668.1 - 1.4e-43 148.9 52.7 1.4e-43 148.9 36.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF74668.1 - 3.3e-13 49.0 44.6 5.5e-12 44.9 10.7 3.1 2 1 1 3 3 3 2 Sugar (and other) transporter TRI12 PF06609.8 EXF74668.1 - 7.3e-12 44.2 29.8 2.1e-11 42.7 20.6 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Peptidase_M3 PF01432.15 EXF74669.1 - 2.1e-118 396.2 0.0 1.1e-117 393.8 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M3 TauD PF02668.11 EXF74670.1 - 1.5e-56 191.9 0.1 1.9e-56 191.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Sugar_tr PF00083.19 EXF74671.1 - 5.7e-128 427.3 29.6 6.5e-128 427.1 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF74671.1 - 1.5e-22 79.8 51.3 7.9e-18 64.2 18.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1399 PF07173.7 EXF74672.1 - 6.8e-16 58.7 1.0 1.1e-15 58.1 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1399) DUF1524 PF07510.6 EXF74673.1 - 3e-15 56.3 0.0 3.7e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) HNH_4 PF13395.1 EXF74673.1 - 0.21 11.2 1.3 5.1 6.8 0.9 2.3 1 1 0 1 1 1 0 HNH endonuclease Glyco_hydro_16 PF00722.16 EXF74674.1 - 4.6e-44 149.9 0.4 9.2e-44 148.9 0.3 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Mucin PF01456.12 EXF74674.1 - 7.1 6.4 24.8 19 5.0 17.2 1.7 1 0 0 1 1 1 0 Mucin-like glycoprotein AAA_18 PF13238.1 EXF74676.1 - 2.5e-14 53.6 0.0 4e-14 53.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EXF74676.1 - 7.9e-13 49.2 0.0 8.8e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain SKI PF01202.17 EXF74676.1 - 1e-12 48.2 0.0 1.3e-12 47.8 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_33 PF13671.1 EXF74676.1 - 6.3e-11 42.3 0.0 7.4e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EXF74676.1 - 1.8e-05 24.8 0.1 3.5e-05 23.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EXF74676.1 - 2.8e-05 23.3 0.0 3.8e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA PF00004.24 EXF74676.1 - 0.00011 22.3 0.2 0.00022 21.4 0.1 1.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CPT PF07931.7 EXF74676.1 - 0.00039 20.0 0.0 0.0031 17.1 0.0 2.0 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein APS_kinase PF01583.15 EXF74676.1 - 0.00052 19.6 0.0 0.00068 19.3 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.1 EXF74676.1 - 0.00065 19.7 0.0 0.0015 18.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EXF74676.1 - 0.00088 19.1 0.0 0.0033 17.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EXF74676.1 - 0.001 18.7 0.2 0.0031 17.2 0.0 1.9 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EXF74676.1 - 0.0015 18.2 0.0 0.003 17.2 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain NTPase_1 PF03266.10 EXF74676.1 - 0.0018 18.0 0.4 0.0069 16.1 0.2 1.9 2 0 0 2 2 2 1 NTPase ABC_tran PF00005.22 EXF74676.1 - 0.0019 18.5 0.0 0.0024 18.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.1 EXF74676.1 - 0.0021 18.0 0.2 0.0047 16.8 0.1 1.6 1 1 0 1 1 1 1 AAA domain CoaE PF01121.15 EXF74676.1 - 0.0028 17.0 0.0 0.0043 16.4 0.0 1.5 1 0 0 1 1 1 1 Dephospho-CoA kinase Sigma54_activ_2 PF14532.1 EXF74676.1 - 0.0031 17.5 0.0 0.0059 16.6 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain T2SE PF00437.15 EXF74676.1 - 0.0036 16.2 0.1 0.0054 15.6 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.11 EXF74676.1 - 0.0038 16.4 0.1 0.0058 15.8 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein RNA_helicase PF00910.17 EXF74676.1 - 0.0039 17.3 0.0 0.0063 16.6 0.0 1.3 1 0 0 1 1 1 1 RNA helicase AAA_23 PF13476.1 EXF74676.1 - 0.0084 16.4 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EXF74676.1 - 0.011 14.8 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 EXF74676.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EXF74676.1 - 0.017 14.6 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EXF74676.1 - 0.018 13.7 0.0 0.022 13.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_29 PF13555.1 EXF74676.1 - 0.02 14.4 0.1 0.035 13.6 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.17 EXF74676.1 - 0.023 13.5 0.0 0.038 12.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_30 PF13604.1 EXF74676.1 - 0.039 13.5 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EXF74676.1 - 0.041 13.5 0.0 0.069 12.8 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase Sigma54_activat PF00158.21 EXF74676.1 - 0.043 13.2 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EXF74676.1 - 0.044 13.1 0.0 0.079 12.3 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein KaiC PF06745.8 EXF74676.1 - 0.049 12.7 0.1 0.1 11.6 0.1 1.4 1 0 0 1 1 1 0 KaiC PIF1 PF05970.9 EXF74676.1 - 0.05 12.5 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase cobW PF02492.14 EXF74676.1 - 0.055 12.9 0.0 0.071 12.5 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF258 PF03193.11 EXF74676.1 - 0.074 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RuvB_N PF05496.7 EXF74676.1 - 0.077 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EXF74676.1 - 0.083 12.2 0.5 0.13 11.6 0.3 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EXF74676.1 - 0.085 12.5 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EXF74676.1 - 0.098 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 EXF74676.1 - 0.11 11.4 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Cytidylate_kin2 PF13189.1 EXF74676.1 - 0.14 12.0 0.1 1.9 8.3 0.0 2.2 1 1 1 2 2 2 0 Cytidylate kinase-like family Aldedh PF00171.17 EXF74677.1 - 1.9e-148 494.6 0.4 2.4e-148 494.3 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EXF74677.1 - 8.4e-05 21.4 0.0 0.00014 20.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EXF74677.1 - 0.0075 15.5 0.0 3.5 6.7 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1487) Romo1 PF10247.4 EXF74677.1 - 0.15 12.2 0.8 0.33 11.1 0.6 1.5 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 Transferase PF02458.10 EXF74678.1 - 1.1e-05 24.0 0.0 4.5e-05 22.0 0.0 1.9 2 1 0 2 2 2 1 Transferase family tRNA-synt_2 PF00152.15 EXF74679.1 - 4.4e-75 252.5 0.0 8.4e-75 251.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) DUF2156 PF09924.4 EXF74679.1 - 4.7e-15 55.1 0.1 6.5e-15 54.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2156) tRNA_anti-codon PF01336.20 EXF74679.1 - 5.5e-08 32.5 0.0 1.5e-07 31.1 0.0 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SR-25 PF10500.4 EXF74679.1 - 0.0051 16.3 13.7 0.0099 15.3 9.5 1.4 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Abhydrolase_3 PF07859.8 EXF74680.1 - 1.6e-43 148.7 0.0 2.4e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EXF74680.1 - 3e-06 26.2 0.0 2.1e-05 23.4 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EXF74680.1 - 1.3e-05 25.0 0.0 2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF74680.1 - 4.9e-05 23.3 0.2 0.0001 22.2 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF74680.1 - 0.00059 19.1 0.0 0.0039 16.4 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 EXF74680.1 - 0.0016 17.8 0.0 1.1 8.5 0.0 2.4 2 0 0 2 2 2 2 Putative esterase Abhydrolase_2 PF02230.11 EXF74680.1 - 0.0057 16.1 0.0 0.013 14.9 0.0 1.5 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase AXE1 PF05448.7 EXF74680.1 - 0.048 12.1 0.0 1 7.7 0.0 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Imm34 PF15596.1 EXF74680.1 - 0.086 13.0 0.7 0.17 12.0 0.5 1.4 1 0 0 1 1 1 0 Immunity protein 34 Methyltransf_23 PF13489.1 EXF74681.1 - 4.4e-18 65.5 0.0 6.2e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF74681.1 - 5.2e-07 29.3 0.0 0.0051 16.4 0.0 2.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EXF74681.1 - 5.9e-07 29.8 0.0 5.3e-06 26.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF74681.1 - 6.6e-07 29.7 0.0 1e-05 25.9 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF74681.1 - 1.3e-05 25.6 0.1 0.00056 20.4 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF74681.1 - 1.6e-05 25.1 0.0 0.0018 18.6 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain CheR PF01739.13 EXF74681.1 - 0.083 12.1 0.0 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Ank_2 PF12796.2 EXF74682.1 - 1.8e-17 63.4 0.0 2.4e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EXF74682.1 - 1.6e-15 56.0 0.1 1.7e-10 40.1 0.4 2.5 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EXF74682.1 - 3.3e-15 56.1 0.4 2.8e-07 30.8 0.0 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF74682.1 - 3.9e-12 45.9 0.6 2.4e-11 43.4 0.2 2.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF74682.1 - 1.7e-11 43.1 0.0 5.6e-08 32.2 0.1 3.4 4 0 0 4 4 4 2 Ankyrin repeat Sec7 PF01369.15 EXF74683.1 - 6.4e-44 149.9 0.0 1.2e-43 149.0 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain PH_9 PF15410.1 EXF74683.1 - 7.2e-18 64.8 0.0 1.6e-17 63.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain FAD_binding_3 PF01494.14 EXF74684.1 - 2e-47 161.9 0.0 2.8e-47 161.4 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF74684.1 - 8.4e-08 31.4 0.0 0.00031 19.7 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.5 EXF74684.1 - 0.0028 16.5 0.0 0.046 12.5 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase Lycopene_cycl PF05834.7 EXF74684.1 - 0.0046 15.9 0.0 0.56 9.0 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EXF74684.1 - 0.0071 16.4 0.0 0.025 14.6 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF74684.1 - 0.011 15.7 0.0 0.032 14.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EXF74684.1 - 0.015 13.8 0.0 0.029 12.8 0.0 1.4 2 0 0 2 2 2 0 HI0933-like protein Thi4 PF01946.12 EXF74684.1 - 0.016 14.3 0.0 0.035 13.1 0.0 1.5 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EXF74684.1 - 0.13 12.0 0.2 11 5.8 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding Dioxygenase_C PF00775.16 EXF74685.1 - 8.4e-50 168.5 0.0 1.2e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EXF74685.1 - 4.6e-17 61.7 0.0 9.7e-17 60.7 0.0 1.5 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EXF74685.1 - 0.00053 19.9 0.2 0.0012 18.8 0.1 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain GCV_T PF01571.16 EXF74686.1 - 2.8e-23 82.3 0.0 3.3e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain DUF2434 PF10361.4 EXF74687.1 - 9e-116 386.0 5.4 1.1e-115 385.7 3.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) YqzM PF14141.1 EXF74687.1 - 9.6 6.0 7.1 2.2 8.1 1.2 2.3 2 0 0 2 2 2 0 YqzM-like protein COG5 PF10392.4 EXF74688.1 - 2.3e-38 131.1 0.6 2.3e-38 131.1 0.4 2.5 3 0 0 3 3 3 1 Golgi transport complex subunit 5 SPX PF03105.14 EXF74688.1 - 0.0023 17.7 0.0 0.0035 17.1 0.0 1.2 1 0 0 1 1 1 1 SPX domain Med10 PF09748.4 EXF74688.1 - 0.029 14.1 0.1 5.8 6.7 0.0 3.1 3 0 0 3 3 3 0 Transcription factor subunit Med10 of Mediator complex DHFR_2 PF06442.6 EXF74688.1 - 0.042 13.4 0.0 0.083 12.5 0.0 1.5 1 0 0 1 1 1 0 R67 dihydrofolate reductase Sec5 PF15469.1 EXF74688.1 - 0.1 12.3 1.0 0.55 9.9 0.2 2.3 3 0 0 3 3 3 0 Exocyst complex component Sec5 IncA PF04156.9 EXF74688.1 - 0.39 10.2 6.3 0.11 12.0 1.5 1.9 2 0 0 2 2 2 0 IncA protein DivIC PF04977.10 EXF74688.1 - 0.4 10.2 2.3 0.97 8.9 1.0 2.1 2 0 0 2 2 2 0 Septum formation initiator p450 PF00067.17 EXF74689.1 - 4.9e-56 190.1 0.0 7.1e-56 189.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RTA1 PF04479.8 EXF74690.1 - 8.6e-34 116.9 10.4 1.1e-33 116.6 7.2 1.0 1 0 0 1 1 1 1 RTA1 like protein DUF996 PF06195.8 EXF74690.1 - 2.6 8.0 12.8 0.097 12.6 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF996) adh_short_C2 PF13561.1 EXF74692.1 - 9.9e-26 90.9 0.0 1.2e-25 90.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EXF74692.1 - 2.9e-23 82.5 0.0 3.6e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF74692.1 - 2.1e-12 47.0 0.0 3.2e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EXF74692.1 - 1.2e-05 24.3 0.0 2.4e-05 23.4 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EXF74692.1 - 4.1e-05 23.1 0.0 5.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF74692.1 - 0.002 18.1 0.0 0.0085 16.1 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding 3Beta_HSD PF01073.14 EXF74692.1 - 0.002 16.8 0.1 0.0062 15.2 0.0 1.6 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 EXF74692.1 - 0.01 16.2 1.0 5.2 7.5 0.3 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EXF74692.1 - 0.013 15.3 0.0 0.33 10.7 0.0 2.2 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox_3 PF13738.1 EXF74692.1 - 0.016 15.2 0.0 0.026 14.5 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EXF74692.1 - 0.027 14.1 0.0 0.075 12.6 0.0 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 EXF74692.1 - 0.037 12.9 0.0 0.072 11.9 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Pyr_redox PF00070.22 EXF74692.1 - 0.055 13.8 0.1 0.17 12.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EXF74692.1 - 0.058 13.3 0.0 0.17 11.8 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Ank_2 PF12796.2 EXF74693.1 - 5.2e-30 103.6 0.0 3.3e-11 43.3 0.0 4.7 3 2 2 5 5 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EXF74693.1 - 1.2e-26 92.5 4.1 1.7e-06 28.3 0.0 6.3 2 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF74693.1 - 7e-23 78.4 0.1 0.00015 21.6 0.0 8.8 8 0 0 8 8 8 5 Ankyrin repeat Ank PF00023.25 EXF74693.1 - 2e-22 77.7 0.2 1.8e-05 24.2 0.0 9.0 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.1 EXF74693.1 - 2.5e-16 59.3 2.2 0.00023 21.2 0.2 6.1 1 1 6 7 7 7 4 Ankyrin repeats (many copies) NACHT PF05729.7 EXF74693.1 - 7.7e-09 35.4 0.0 2.2e-08 33.9 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EXF74693.1 - 4.2e-06 26.8 0.5 2.9e-05 24.1 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EXF74693.1 - 2.6e-05 24.3 0.0 9.3e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 EXF74693.1 - 5e-05 22.4 0.3 0.12 11.3 0.3 2.6 1 1 1 2 2 2 2 KAP family P-loop domain NB-ARC PF00931.17 EXF74693.1 - 0.024 13.4 0.0 0.046 12.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.24 EXF74693.1 - 0.041 14.0 0.0 0.27 11.4 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EXF74693.1 - 0.13 13.1 0.0 23 5.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain Rifin_STEVOR PF02009.11 EXF74694.1 - 0.016 14.8 0.1 0.11 12.0 0.0 2.1 2 0 0 2 2 2 0 Rifin/stevor family Ycf1 PF05758.7 EXF74694.1 - 0.083 10.6 2.0 0.052 11.2 0.3 1.4 2 0 0 2 2 2 0 Ycf1 SCF PF02404.10 EXF74694.1 - 0.22 10.6 0.6 0.9 8.6 0.0 1.9 2 0 0 2 2 2 0 Stem cell factor SAPS PF04499.10 EXF74694.1 - 1.4 7.4 5.2 0.17 10.4 0.8 1.4 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein OAD_gamma PF04277.8 EXF74694.1 - 1.7 9.0 0.0 1.7 9.0 0.0 5.5 3 2 1 4 4 4 0 Oxaloacetate decarboxylase, gamma chain TFIIF_alpha PF05793.7 EXF74694.1 - 3.5 5.8 19.2 7.4 4.8 13.3 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) cobW PF02492.14 EXF74695.1 - 2.3e-48 163.9 5.1 3.5e-35 121.0 0.3 2.2 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EXF74695.1 - 3.7e-17 61.8 0.0 6.5e-14 51.4 0.0 2.6 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain ArgK PF03308.11 EXF74695.1 - 7.8e-06 24.8 1.0 0.00067 18.5 0.0 2.3 2 0 0 2 2 2 1 ArgK protein CbiA PF01656.18 EXF74695.1 - 0.0013 18.2 0.3 0.0028 17.1 0.0 1.7 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.1 EXF74695.1 - 0.0017 18.2 0.2 0.1 12.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain MobB PF03205.9 EXF74695.1 - 0.0033 17.1 0.0 0.0071 16.0 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 EXF74695.1 - 0.0077 15.7 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.1 EXF74695.1 - 0.0078 16.2 3.2 0.04 13.9 0.5 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EXF74695.1 - 0.024 14.7 0.0 0.088 12.9 0.0 2.0 2 0 0 2 2 1 0 AAA domain Nop14 PF04147.7 EXF74695.1 - 0.026 12.4 12.1 0.041 11.8 8.4 1.2 1 0 0 1 1 1 0 Nop14-like family AAA_10 PF12846.2 EXF74695.1 - 0.044 13.2 0.0 0.087 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_11 PF13086.1 EXF74695.1 - 0.053 13.0 2.5 0.46 10.0 0.0 2.7 2 1 0 3 3 3 0 AAA domain UPF0079 PF02367.12 EXF74695.1 - 0.06 12.9 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 DUF3396 PF11876.3 EXF74695.1 - 0.098 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3396) AAA_29 PF13555.1 EXF74695.1 - 0.099 12.1 0.2 0.26 10.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 EXF74695.1 - 0.15 11.6 0.5 0.37 10.4 0.1 1.9 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.1 EXF74695.1 - 0.34 11.2 0.0 0.34 11.2 0.0 3.5 3 0 0 3 3 3 0 AAA domain Daxx PF03344.10 EXF74695.1 - 1.3 7.3 16.8 2.1 6.7 11.7 1.2 1 0 0 1 1 1 0 Daxx Family TRAP_alpha PF03896.11 EXF74695.1 - 5.3 5.9 10.6 10 5.0 7.4 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CDC45 PF02724.9 EXF74695.1 - 5.5 4.8 14.6 9 4.1 10.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3295 PF11702.3 EXF74695.1 - 7.6 5.3 11.8 12 4.7 8.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Glyco_hydro_61 PF03443.9 EXF74696.1 - 6.8e-49 166.6 0.1 9.2e-49 166.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 A2M_N PF01835.14 EXF74696.1 - 0.0049 17.0 0.0 0.0093 16.1 0.0 1.4 1 0 0 1 1 1 1 MG2 domain HET PF06985.6 EXF74697.1 - 4.6e-29 101.3 0.0 9.6e-29 100.3 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4003 PF13170.1 EXF74697.1 - 0.069 12.3 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) Pyr_redox_3 PF13738.1 EXF74698.1 - 5.2e-22 78.8 0.0 2.5e-21 76.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EXF74698.1 - 5.7e-13 47.9 0.4 2.3e-10 39.3 0.1 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EXF74698.1 - 2.3e-10 39.9 0.0 6.7e-07 28.5 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EXF74698.1 - 2.8e-09 37.1 0.0 2.2e-07 30.9 0.0 3.0 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF74698.1 - 1.5e-06 28.1 0.0 8.9e-06 25.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EXF74698.1 - 1.8e-05 23.9 0.0 0.0025 16.9 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.14 EXF74698.1 - 2.7e-05 23.3 0.1 0.00089 18.4 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EXF74698.1 - 0.00014 22.1 0.0 0.64 10.4 0.0 3.0 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF74698.1 - 0.00043 20.0 0.0 0.066 12.9 0.0 3.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding 3HCDH_N PF02737.13 EXF74698.1 - 0.00048 19.8 0.2 0.25 10.9 0.0 2.3 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 EXF74698.1 - 0.00088 18.4 0.0 0.017 14.2 0.0 2.3 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EXF74698.1 - 0.0014 17.5 0.1 0.0084 15.0 0.1 2.2 3 0 0 3 3 3 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EXF74698.1 - 0.0045 15.5 0.1 0.012 14.0 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EXF74698.1 - 0.0046 15.8 0.4 0.015 14.1 0.4 1.7 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EXF74698.1 - 0.0065 15.4 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein SnoaL_2 PF12680.2 EXF74698.1 - 0.008 16.5 0.0 0.02 15.2 0.0 1.8 1 0 0 1 1 1 1 SnoaL-like domain IlvN PF07991.7 EXF74698.1 - 0.014 14.8 0.1 0.85 8.9 0.0 2.4 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain SnoaL_4 PF13577.1 EXF74698.1 - 0.018 14.9 0.0 0.041 13.8 0.0 1.7 1 0 0 1 1 1 0 SnoaL-like domain TrkA_N PF02254.13 EXF74698.1 - 0.019 14.9 0.1 0.26 11.3 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Shikimate_DH PF01488.15 EXF74698.1 - 0.037 14.1 0.0 5.6 7.0 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF917 PF06032.7 EXF74700.1 - 5.1e-113 377.2 0.1 1.3e-112 375.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EXF74700.1 - 6.8e-49 166.5 6.1 6.8e-49 166.5 4.2 2.3 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EXF74700.1 - 2.8e-17 62.7 0.7 8.6e-16 57.9 0.0 2.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region StbA PF06406.6 EXF74700.1 - 0.053 12.4 0.1 1.9 7.3 0.0 2.6 2 0 0 2 2 2 0 StbA protein Transp_cyt_pur PF02133.10 EXF74701.1 - 2.2e-100 336.3 29.3 2.5e-100 336.1 20.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Tyrosinase PF00264.15 EXF74702.1 - 2.2e-45 155.5 0.0 3.2e-45 155.0 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Fungal_trans_2 PF11951.3 EXF74703.1 - 1.3e-14 53.6 0.2 2e-14 53.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EXF74704.1 - 6.6e-14 51.4 0.0 1.2e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF74704.1 - 1.3e-08 34.5 10.4 2e-08 33.9 7.2 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HET PF06985.6 EXF74705.1 - 9.7e-23 80.8 0.3 3.9e-22 78.9 0.2 2.1 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MIG-14_Wnt-bd PF06664.7 EXF74707.1 - 0.0028 16.5 0.3 0.0038 16.1 0.2 1.1 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion DUF2892 PF11127.3 EXF74707.1 - 0.47 10.3 3.8 0.54 10.1 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) LRR_8 PF13855.1 EXF74708.1 - 4.7e-32 109.5 31.2 9.4e-09 34.9 2.5 8.4 4 2 7 11 11 11 10 Leucine rich repeat LRR_4 PF12799.2 EXF74708.1 - 9e-32 108.1 37.7 3e-07 29.9 3.3 9.7 5 2 4 10 10 10 9 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EXF74708.1 - 4.1e-14 50.4 34.5 0.15 12.2 0.1 14.3 15 1 0 15 15 15 4 Leucine Rich Repeat LRR_7 PF13504.1 EXF74708.1 - 2.6e-05 23.7 36.9 1.1 9.7 0.1 12.2 14 0 0 14 14 14 3 Leucine rich repeat LRR_6 PF13516.1 EXF74708.1 - 0.018 15.0 21.8 13 6.2 0.9 8.2 7 2 2 9 9 9 0 Leucine Rich repeat LRR_9 PF14580.1 EXF74708.1 - 1.4 8.4 11.0 20 4.7 0.0 4.8 2 2 4 6 6 6 0 Leucine-rich repeat Pec_lyase_C PF00544.14 EXF74709.1 - 3.2e-14 52.8 10.9 2.3e-09 37.0 2.2 2.3 1 1 1 2 2 2 2 Pectate lyase Coatomer_b_Cpla PF14806.1 EXF74709.1 - 0.089 12.4 0.2 0.66 9.6 0.0 2.1 1 1 1 2 2 2 0 Coatomer beta subunit appendage platform Flavokinase PF01687.12 EXF74710.1 - 3e-31 107.8 0.0 3.6e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase PAS PF00989.19 EXF74711.1 - 4.5e-05 23.1 0.0 0.0001 22.0 0.0 1.6 1 0 0 1 1 1 1 PAS fold Zn_clus PF00172.13 EXF74711.1 - 0.0028 17.5 8.8 0.0064 16.3 6.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EXF74713.1 - 3e-34 118.2 40.2 4.4e-34 117.7 27.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF74713.1 - 2e-14 53.0 7.6 2e-14 53.0 5.3 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EXF74713.1 - 3.5e-08 32.1 3.5 5.9e-08 31.3 2.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2370 PF10176.4 EXF74713.1 - 0.17 11.2 0.1 0.6 9.4 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Cellulase PF00150.13 EXF74714.1 - 7.9e-10 38.3 1.9 7.9e-10 38.3 1.3 1.5 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) EphA2_TM PF14575.1 EXF74714.1 - 0.0017 18.6 0.0 0.0052 17.1 0.0 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF3357 PF11837.3 EXF74714.1 - 0.0027 17.5 0.0 0.011 15.5 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) Adipogenin PF15202.1 EXF74714.1 - 0.0083 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Adipogenin Radical_SAM PF04055.16 EXF74714.1 - 0.05 13.7 0.0 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 Radical SAM superfamily Ninjurin PF04923.7 EXF74714.1 - 0.073 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Ninjurin SP_C-Propep PF08999.5 EXF74714.1 - 0.2 11.1 0.8 0.45 10.0 0.6 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide 4HB_MCP_1 PF12729.2 EXF74714.1 - 0.23 10.8 2.2 0.45 9.8 1.5 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction F-actin_cap_A PF01267.12 EXF74715.1 - 1.4e-94 316.1 0.0 1.8e-94 315.7 0.0 1.1 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Transket_pyr PF02779.19 EXF74715.1 - 1.4e-42 145.2 0.0 2.3e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EXF74715.1 - 9.4e-33 112.7 0.1 2.5e-32 111.3 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain Cyt-b5 PF00173.23 EXF74716.1 - 1.3e-24 85.8 0.2 1.7e-24 85.4 0.2 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AIF-MLS PF14962.1 EXF74716.1 - 0.027 14.1 0.1 0.039 13.6 0.1 1.3 1 0 0 1 1 1 0 Mitochondria Localisation Sequence DUF2201 PF09967.4 EXF74716.1 - 0.044 13.8 0.0 0.057 13.4 0.0 1.1 1 0 0 1 1 1 0 VWA-like domain (DUF2201) TFIIE_beta PF02186.10 EXF74717.1 - 0.00015 21.6 0.0 0.0003 20.7 0.0 1.5 1 0 0 1 1 1 1 TFIIE beta subunit core domain FAM220 PF15487.1 EXF74717.1 - 0.14 11.5 7.9 0.015 14.6 2.4 1.6 2 0 0 2 2 2 0 FAM220 family DSBA PF01323.15 EXF74718.1 - 2e-18 66.6 0.1 2.2e-18 66.5 0.1 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.1 EXF74718.1 - 1.5e-05 25.0 0.0 1.5e-05 25.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin DUF2379 PF09543.5 EXF74718.1 - 0.054 13.4 0.4 0.074 13.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2379) Thioredoxin_2 PF13098.1 EXF74718.1 - 0.11 12.7 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain SGL PF08450.7 EXF74719.1 - 2.1e-68 230.3 0.0 2.7e-68 230.0 0.0 1.1 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EXF74719.1 - 0.016 15.1 0.0 0.041 13.8 0.0 1.6 1 0 0 1 1 1 0 Arylesterase Reg_prop PF07494.6 EXF74719.1 - 0.036 14.0 0.3 0.89 9.7 0.0 2.8 2 0 0 2 2 2 0 Two component regulator propeller PD40 PF07676.7 EXF74719.1 - 0.14 11.8 0.2 0.45 10.2 0.0 1.9 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat N2227 PF07942.7 EXF74721.1 - 3.1e-60 203.4 0.0 8.7e-60 201.9 0.0 1.6 2 0 0 2 2 2 1 N2227-like protein Methyltransf_11 PF08241.7 EXF74721.1 - 0.00012 22.5 0.0 0.0004 20.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF74721.1 - 0.00015 22.2 0.1 0.001 19.4 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF74721.1 - 0.00021 21.0 0.0 0.00058 19.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF74721.1 - 0.00043 20.8 0.0 0.0013 19.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF74721.1 - 0.0083 15.7 0.0 0.21 11.1 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF74721.1 - 0.072 13.1 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain NFRKB_winged PF14465.1 EXF74721.1 - 0.081 12.7 0.0 0.53 10.1 0.0 2.2 2 0 0 2 2 2 0 NFRKB Winged Helix-like Methyltransf_24 PF13578.1 EXF74721.1 - 0.094 13.5 0.4 0.58 11.0 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain Cellulase PF00150.13 EXF74722.1 - 9.8e-32 110.2 0.1 1.5e-31 109.7 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) TCTP PF00838.12 EXF74722.1 - 0.13 12.2 0.1 0.25 11.3 0.0 1.4 1 0 0 1 1 1 0 Translationally controlled tumour protein Sugar_tr PF00083.19 EXF74724.1 - 1.9e-76 257.4 23.1 2.2e-76 257.2 16.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF74724.1 - 4e-17 61.9 29.6 3.5e-09 35.8 3.5 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EXF74724.1 - 3.2e-07 29.1 25.1 0.00039 18.9 0.3 4.2 2 2 2 4 4 4 2 MFS/sugar transport protein VCBS PF13517.1 EXF74727.1 - 5.8e-06 26.5 21.0 0.00031 21.0 3.7 6.2 5 1 1 6 6 6 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EXF74727.1 - 0.0035 16.9 1.1 0.0035 16.9 0.8 5.8 6 0 0 6 6 6 3 FG-GAP repeat p450 PF00067.17 EXF74728.1 - 1.2e-45 155.9 0.0 1.4e-45 155.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ICL PF00463.16 EXF74729.1 - 1.9e-115 386.0 0.0 2.3e-115 385.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EXF74729.1 - 7.8e-08 31.8 0.0 1.3e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Aminotran_1_2 PF00155.16 EXF74730.1 - 1.1e-18 67.3 0.0 1.4e-18 67.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EXF74730.1 - 0.00049 18.7 0.0 0.00092 17.8 0.0 1.4 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase MFS_1 PF07690.11 EXF74731.1 - 1.7e-32 112.5 20.4 1.7e-32 112.5 14.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EXF74731.1 - 0.0059 16.3 1.7 0.0078 15.9 0.1 2.1 2 0 0 2 2 2 1 MFS_1 like family PsbJ PF01788.12 EXF74731.1 - 0.0076 15.7 0.4 0.023 14.2 0.3 1.8 1 0 0 1 1 1 1 PsbJ HpcH_HpaI PF03328.9 EXF74732.1 - 1.5e-27 95.9 1.2 2.2e-27 95.4 0.9 1.2 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Tetraspannin PF00335.15 EXF74733.1 - 0.02 14.1 6.8 0.21 10.8 4.7 2.2 1 1 0 1 1 1 0 Tetraspanin family DUF2892 PF11127.3 EXF74733.1 - 6.3 6.7 8.0 15 5.5 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2892) PI-PLC-X PF00388.14 EXF74734.1 - 1.7e-48 163.7 0.0 2.7e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EXF74734.1 - 6.1e-32 110.0 0.0 1e-31 109.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain ANAPC15 PF15243.1 EXF74734.1 - 0.0086 16.1 0.6 0.098 12.7 0.3 2.3 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 15 C2 PF00168.25 EXF74734.1 - 0.041 13.7 1.2 0.16 11.7 0.4 2.3 2 1 0 2 2 2 0 C2 domain Asp-Al_Ex PF06826.7 EXF74735.1 - 0.023 14.2 0.1 0.039 13.4 0.1 1.3 1 0 0 1 1 1 0 Predicted Permease Membrane Region PRA1 PF03208.14 EXF74736.1 - 8.6e-38 129.0 0.5 1.6e-37 128.2 0.3 1.3 1 0 0 1 1 1 1 PRA1 family protein Nop14 PF04147.7 EXF74736.1 - 0.08 10.8 15.5 0.14 10.0 10.8 1.3 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EXF74736.1 - 0.2 9.6 18.6 0.42 8.5 12.9 1.5 1 0 0 1 1 1 0 CDC45-like protein TT_ORF1 PF02956.9 EXF74736.1 - 4 5.7 13.2 5.7 5.2 9.2 1.2 1 0 0 1 1 1 0 TT viral orf 1 NOA36 PF06524.7 EXF74736.1 - 4.8 6.3 8.6 9.1 5.4 6.0 1.4 1 0 0 1 1 1 0 NOA36 protein Myb_DNA-bind_5 PF13873.1 EXF74737.1 - 0.063 13.1 0.3 0.14 12.0 0.2 1.5 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain Nucleoporin_FG PF13634.1 EXF74737.1 - 0.3 11.3 7.3 0.1 12.8 2.1 2.0 2 0 0 2 2 2 0 Nucleoporin FG repeat region DUF1509 PF07420.6 EXF74737.1 - 8.5 5.5 11.5 11 5.1 7.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) DUF3401 PF11881.3 EXF74738.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3401) SurE PF01975.12 EXF74739.1 - 9.6e-42 142.5 0.0 1.3e-41 142.1 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE CRAM_rpt PF07016.6 EXF74739.1 - 0.14 11.4 2.7 0.24 10.7 1.9 1.3 1 0 0 1 1 1 0 Cysteine-rich acidic integral membrane protein precursor Pil1 PF13805.1 EXF74740.1 - 0.028 13.5 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 Eisosome component PIL1 Zn_clus PF00172.13 EXF74740.1 - 0.24 11.3 8.0 0.49 10.3 5.5 1.5 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain DPPIV_N PF00930.16 EXF74741.1 - 2.9e-105 351.7 0.3 2.9e-105 351.7 0.2 1.9 3 0 0 3 3 3 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EXF74741.1 - 6.9e-52 175.7 2.7 1.4e-51 174.7 1.9 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EXF74741.1 - 2e-08 34.0 0.2 4e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF74741.1 - 2.1e-06 27.7 0.6 2.4e-05 24.3 0.4 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EXF74741.1 - 2.9e-05 23.6 2.9 0.00022 20.7 0.8 2.3 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Clathrin PF00637.15 EXF74742.1 - 4.8e-204 668.1 30.2 4.5e-34 117.0 1.2 7.7 7 1 1 8 8 8 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 EXF74742.1 - 1.8e-32 109.3 1.7 1.2e-05 25.2 0.0 7.6 7 0 0 7 7 7 6 Clathrin propeller repeat Clathrin_H_link PF13838.1 EXF74742.1 - 9.5e-30 102.2 0.8 4e-29 100.3 0.6 2.2 1 0 0 1 1 1 1 Clathrin-H-link TPR_12 PF13424.1 EXF74742.1 - 0.00022 21.0 1.0 2.9 7.8 0.0 5.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EXF74742.1 - 0.00076 19.1 5.4 19 5.3 0.0 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.1 EXF74742.1 - 0.0098 16.4 10.0 60 4.6 0.0 8.3 11 1 2 13 13 13 0 Tetratricopeptide repeat Clathrin-link PF09268.5 EXF74742.1 - 0.038 13.0 0.2 0.12 11.4 0.1 2.0 1 0 0 1 1 1 0 Clathrin, heavy-chain linker Ank PF00023.25 EXF74742.1 - 0.074 12.8 0.1 15 5.6 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeat PPR PF01535.15 EXF74742.1 - 0.08 12.9 0.1 28 4.9 0.0 4.7 4 0 0 4 4 4 0 PPR repeat DUF1640 PF07798.6 EXF74744.1 - 1.2e-64 217.5 7.2 1.9e-64 216.9 5.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) cwf21 PF08312.7 EXF74744.1 - 0.016 15.0 1.5 0.05 13.4 1.0 1.9 1 1 0 1 1 1 0 cwf21 domain Lzipper-MIP1 PF14389.1 EXF74744.1 - 0.019 15.0 2.4 6.3 6.9 0.9 2.5 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Metal_resist PF13801.1 EXF74744.1 - 0.11 12.5 4.4 0.31 11.0 0.2 2.6 3 0 0 3 3 3 0 Heavy-metal resistance Syntaxin PF00804.20 EXF74744.1 - 0.6 10.3 9.1 0.15 12.2 1.6 2.7 1 1 2 3 3 3 0 Syntaxin MFS_1 PF07690.11 EXF74745.1 - 3.8e-29 101.4 24.4 3.8e-29 101.4 16.9 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF74745.1 - 2.1e-15 56.2 0.0 2.1e-15 56.2 0.0 2.5 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EXF74745.1 - 4.1e-05 22.1 6.4 4.1e-05 22.1 4.4 3.4 3 1 1 4 4 4 2 MFS/sugar transport protein MFS_3 PF05977.8 EXF74745.1 - 0.0015 16.7 8.1 0.049 11.7 1.7 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector FAD_binding_4 PF01565.18 EXF74747.1 - 9.2e-21 73.7 2.0 2.1e-20 72.6 1.4 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF74747.1 - 8.9e-11 41.5 0.4 2.1e-10 40.3 0.3 1.7 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EXF74747.1 - 0.0035 16.5 0.0 0.0065 15.6 0.0 1.4 1 0 0 1 1 1 1 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF3632 PF12311.3 EXF74748.1 - 1.1e-09 38.3 0.0 2e-08 34.2 0.0 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) TRP PF06011.7 EXF74749.1 - 1.8e-33 115.8 17.8 2.3e-32 112.1 12.3 2.5 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel MscL PF01741.13 EXF74749.1 - 0.085 12.9 0.0 0.19 11.8 0.0 1.5 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL HemY_N PF07219.8 EXF74749.1 - 0.21 11.1 6.0 4.6 6.8 0.2 3.5 3 0 0 3 3 3 0 HemY protein N-terminus DUF2254 PF10011.4 EXF74749.1 - 2.9 6.2 7.9 5.4 5.3 0.4 3.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2254) WSC PF01822.14 EXF74750.1 - 3.6e-52 174.2 66.1 1.5e-19 69.7 7.4 5.5 5 0 0 5 5 5 4 WSC domain Peptidase_M20 PF01546.23 EXF74751.1 - 8.6e-21 74.2 0.0 1.3e-20 73.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EXF74751.1 - 1.9e-05 24.3 0.0 4.6e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Chitin_bind_3 PF03067.10 EXF74752.1 - 8.9e-15 55.4 0.6 1.2e-14 55.0 0.4 1.2 1 0 0 1 1 1 1 Chitin binding domain Serglycin PF04360.7 EXF74752.1 - 0.019 14.7 0.8 0.032 13.9 0.5 1.5 1 0 0 1 1 1 0 Serglycin DHDPS PF00701.17 EXF74753.1 - 1.2e-13 50.2 0.1 1.7e-08 33.4 0.0 2.0 1 1 1 2 2 2 2 Dihydrodipicolinate synthetase family Methyltransf_23 PF13489.1 EXF74754.1 - 3.3e-08 33.4 0.0 5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF74754.1 - 8.8e-05 22.1 0.0 0.00075 19.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF74754.1 - 0.011 16.2 0.0 0.17 12.4 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EXF74754.1 - 0.017 15.5 0.0 0.042 14.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EXF74754.1 - 0.045 14.2 0.0 0.16 12.4 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EXF74754.1 - 0.083 12.9 0.0 0.3 11.1 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain DUF2976 PF11190.3 EXF74755.1 - 0.15 11.5 2.1 5 6.7 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) zf-DHHC PF01529.15 EXF74755.1 - 1.1 8.5 8.0 16 4.8 5.6 2.6 1 1 0 1 1 1 0 DHHC palmitoyltransferase Amelin PF05111.7 EXF74756.1 - 0.11 11.2 0.2 0.17 10.6 0.2 1.3 1 0 0 1 1 1 0 Ameloblastin precursor (Amelin) PAN_4 PF14295.1 EXF74757.1 - 3.1e-06 26.7 0.7 5.8e-06 25.9 0.5 1.5 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.21 EXF74757.1 - 0.0025 17.5 1.4 0.0041 16.8 0.0 2.0 2 0 0 2 2 2 1 PAN domain PBP1_TM PF14812.1 EXF74757.1 - 0.036 14.3 0.0 0.089 13.1 0.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Herpes_US9 PF06072.6 EXF74757.1 - 0.049 13.4 0.0 0.095 12.5 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 PALP PF00291.20 EXF74759.1 - 1e-27 97.2 0.1 1.3e-27 96.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF1517 PF07466.6 EXF74761.1 - 2.8 6.8 8.2 4.3 6.2 5.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) ADH_zinc_N PF00107.21 EXF74762.1 - 1.3e-14 53.8 0.9 4.4e-14 52.1 0.7 1.9 1 1 1 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF74762.1 - 2.6e-13 49.7 0.8 2.6e-13 49.7 0.6 2.0 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 EXF74762.1 - 0.017 15.0 0.3 0.04 13.9 0.2 1.6 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox_2 PF07992.9 EXF74762.1 - 0.051 13.4 0.2 0.082 12.7 0.2 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.9 EXF74762.1 - 0.1 12.0 0.1 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_zinc_N_2 PF13602.1 EXF74762.1 - 0.12 13.2 1.0 0.5 11.2 0.3 2.4 2 1 0 2 2 2 0 Zinc-binding dehydrogenase 3HCDH_N PF02737.13 EXF74762.1 - 0.13 11.8 0.5 0.29 10.7 0.4 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EXF74762.1 - 0.16 12.2 1.3 1.8 8.8 0.9 2.2 1 1 0 1 1 1 0 Putative NAD(P)-binding Fungal_trans PF04082.13 EXF74763.1 - 1.2e-34 119.4 0.1 1.8e-34 118.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_5 PF00266.14 EXF74764.1 - 5.8e-34 117.4 0.0 1.2e-33 116.3 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EXF74764.1 - 0.00066 18.7 0.0 0.0015 17.5 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EXF74764.1 - 0.0069 15.4 0.1 0.011 14.7 0.1 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family AA_permease PF00324.16 EXF74765.1 - 1.1e-111 373.5 43.2 1.3e-111 373.3 30.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF74765.1 - 2.2e-30 105.5 45.6 2.8e-30 105.2 31.6 1.1 1 0 0 1 1 1 1 Amino acid permease Sugar_tr PF00083.19 EXF74766.1 - 4.9e-32 111.0 36.3 5.4e-18 64.8 9.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EXF74766.1 - 3.4e-14 52.3 54.6 5.8e-12 44.9 19.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CVNH PF08881.5 EXF74767.1 - 1.1e-11 44.9 0.0 1.4e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 CVNH domain 2OG-FeII_Oxy_3 PF13640.1 EXF74768.1 - 8.8e-10 39.0 0.0 1.7e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EXF74768.1 - 2e-06 27.3 0.0 6.9e-06 25.6 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily p450 PF00067.17 EXF74769.1 - 8.3e-79 265.2 0.0 1e-78 264.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Dioxygenase_C PF00775.16 EXF74770.1 - 3.6e-12 45.9 0.1 6.4e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 Dioxygenase Phytase PF02333.10 EXF74771.1 - 3.6e-59 200.3 3.0 7.2e-59 199.4 0.5 2.0 2 0 0 2 2 2 1 Phytase EGF_2 PF07974.8 EXF74771.1 - 1.1e-05 25.4 32.7 0.0068 16.5 9.6 2.5 2 0 0 2 2 2 2 EGF-like domain DUF3312 PF11768.3 EXF74771.1 - 0.14 10.3 0.0 0.2 9.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3312) RVT_1 PF00078.22 EXF74772.1 - 4.2e-06 26.2 0.0 1.2e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exonuc_VII_L PF02601.10 EXF74772.1 - 0.1 11.7 1.2 0.24 10.5 0.8 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit MFS_1 PF07690.11 EXF74773.1 - 5e-23 81.3 57.1 9.9e-23 80.4 28.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3814 PF12769.2 EXF74773.1 - 0.54 10.4 8.9 0.094 12.8 2.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3814) NmrA PF05368.8 EXF74774.1 - 9.9e-26 90.4 0.7 1.3e-25 90.0 0.5 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF74774.1 - 1.7e-20 73.8 0.8 2.6e-20 73.1 0.5 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF74774.1 - 1.3e-09 37.8 0.1 1.9e-07 30.7 0.1 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EXF74774.1 - 2.4e-05 23.1 0.1 5.8e-05 21.9 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EXF74774.1 - 0.00011 21.2 0.4 0.00011 21.2 0.3 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase RmlD_sub_bind PF04321.12 EXF74774.1 - 0.0017 17.3 0.4 0.0092 14.8 0.1 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain Semialdhyde_dh PF01118.19 EXF74774.1 - 0.0022 18.3 1.8 0.0024 18.1 0.3 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain CoA_binding_2 PF13380.1 EXF74774.1 - 0.003 17.7 0.5 0.006 16.7 0.3 1.5 1 0 0 1 1 1 1 CoA binding domain DapB_N PF01113.15 EXF74774.1 - 0.003 17.4 0.4 0.0059 16.5 0.3 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_7 PF13241.1 EXF74774.1 - 0.0072 16.5 0.5 0.016 15.4 0.3 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding adh_short PF00106.20 EXF74774.1 - 0.025 14.4 1.9 0.04 13.8 1.3 1.3 1 0 0 1 1 1 0 short chain dehydrogenase 3HCDH_N PF02737.13 EXF74774.1 - 0.032 13.9 1.0 0.066 12.8 0.7 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CPSase_L_chain PF00289.17 EXF74774.1 - 0.075 13.1 0.3 0.16 12.0 0.1 1.6 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain THF_DHG_CYH_C PF02882.14 EXF74774.1 - 0.099 11.7 0.8 0.24 10.4 0.3 2.0 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DFP PF04127.10 EXF74774.1 - 0.21 11.1 4.6 0.065 12.8 0.8 1.8 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Meth_synt_2 PF01717.13 EXF74775.1 - 0.088 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Cobalamin-independent synthase, Catalytic domain SIR2 PF02146.12 EXF74778.1 - 1.2e-29 103.3 0.1 6.5e-23 81.3 0.0 2.2 1 1 1 2 2 2 2 Sir2 family MFS_1 PF07690.11 EXF74779.1 - 8.4e-25 87.2 46.9 9.5e-22 77.1 24.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EXF74779.1 - 0.025 14.3 0.5 0.025 14.3 0.4 3.0 4 0 0 4 4 4 0 MFS_1 like family DUF2678 PF10856.3 EXF74779.1 - 0.04 13.6 0.1 0.15 11.7 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) Mem_trans PF03547.13 EXF74779.1 - 0.39 8.9 4.4 0.085 11.1 0.2 1.9 2 0 0 2 2 2 0 Membrane transport protein Glyco_hydro_61 PF03443.9 EXF74781.1 - 1.8e-77 260.0 0.2 3.5e-77 259.1 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EXF74781.1 - 5.9e-13 48.2 13.9 1.7e-12 46.7 9.6 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain 2OG-FeII_Oxy PF03171.15 EXF74782.1 - 0.00086 19.5 0.0 0.0016 18.7 0.0 1.5 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EXF74782.1 - 0.068 13.6 0.0 0.14 12.6 0.0 1.6 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Fungal_trans_2 PF11951.3 EXF74783.1 - 1.6e-12 46.7 0.0 4.9e-12 45.1 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain V-set_CD47 PF08204.6 EXF74784.1 - 0.03 14.0 0.1 0.055 13.2 0.0 1.5 1 0 0 1 1 1 0 CD47 immunoglobulin-like domain Tannase PF07519.6 EXF74785.1 - 2.6e-95 319.8 0.4 3.1e-95 319.6 0.3 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase DSBA PF01323.15 EXF74786.1 - 5.2e-11 42.4 0.0 5.4e-11 42.4 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain zf-C2H2 PF00096.21 EXF74787.1 - 6.1e-23 79.7 24.8 1.5e-05 25.0 0.1 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EXF74787.1 - 1.2e-21 75.8 26.1 3.1e-07 30.3 0.7 5.5 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EXF74787.1 - 1.2e-15 56.5 23.8 0.00028 20.9 2.6 4.7 4 0 0 4 4 4 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EXF74787.1 - 1.2e-06 28.4 2.7 1.5 9.0 0.0 4.5 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EXF74787.1 - 0.0018 18.3 9.3 2.1 8.6 0.0 4.1 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2HC_2 PF13913.1 EXF74787.1 - 0.014 15.0 6.8 1.2 8.9 0.1 3.7 3 0 0 3 3 3 0 zinc-finger of a C2HC-type C1_4 PF07975.7 EXF74787.1 - 0.043 13.8 0.3 2.1 8.4 0.0 2.6 2 1 1 3 3 3 0 TFIIH C1-like domain XPA_N PF01286.13 EXF74787.1 - 0.089 12.4 0.3 0.089 12.4 0.2 3.3 4 0 0 4 4 4 0 XPA protein N-terminal zf-C2H2_6 PF13912.1 EXF74787.1 - 0.11 12.4 21.4 1.4 8.8 0.8 4.6 5 0 0 5 5 5 0 C2H2-type zinc finger Zn-ribbon_8 PF09723.5 EXF74787.1 - 0.15 12.0 11.4 8.9 6.3 1.4 3.8 2 1 1 3 3 3 0 Zinc ribbon domain C1_1 PF00130.17 EXF74787.1 - 2.8 7.7 6.7 1.1 9.0 1.1 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Methyltransf_33 PF10017.4 EXF74788.1 - 1.3e-22 80.0 0.1 1.9e-22 79.4 0.1 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Fungal_trans_2 PF11951.3 EXF74789.1 - 1.4e-23 83.1 0.3 2.3e-23 82.4 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Nucleo_P87 PF07267.6 EXF74790.1 - 0.041 12.5 1.8 0.05 12.2 1.2 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MitMem_reg PF13012.1 EXF74790.1 - 0.062 13.3 0.6 0.17 11.9 0.2 1.8 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function DUF3682 PF12446.3 EXF74790.1 - 0.86 9.9 7.0 1.3 9.3 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) DAO PF01266.19 EXF74792.1 - 2.6e-38 131.8 0.0 3.7e-38 131.3 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF74792.1 - 0.0026 17.6 0.0 0.5 10.2 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF74792.1 - 0.021 14.8 0.0 0.11 12.5 0.0 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DHBP_synthase PF00926.14 EXF74793.1 - 3.7e-69 231.8 0.0 1.7e-68 229.7 0.0 1.8 1 1 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase Methyltransf_23 PF13489.1 EXF74794.1 - 1.5e-17 63.7 0.0 2.4e-17 63.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF74794.1 - 3.4e-16 59.4 0.0 5.9e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF74794.1 - 3.8e-12 46.7 0.0 6e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF74794.1 - 1.1e-11 44.4 0.0 1.6e-11 44.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF74794.1 - 3.7e-11 43.3 0.0 6e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF74794.1 - 4.2e-07 30.0 0.1 1.7e-06 28.0 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF74794.1 - 1.3e-06 28.6 0.0 2.2e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EXF74794.1 - 0.00022 20.4 0.0 0.00029 20.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EXF74794.1 - 0.0014 18.0 0.0 0.0022 17.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EXF74794.1 - 0.022 13.8 0.0 0.062 12.3 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase SR-25 PF10500.4 EXF74794.1 - 6.1 6.2 6.0 9.3 5.6 4.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NIR_SIR PF01077.17 EXF74795.1 - 5.2e-29 100.6 0.0 8.9e-29 99.8 0.0 1.4 1 0 0 1 1 1 1 Nitrite and sulphite reductase 4Fe-4S domain Pyr_redox_2 PF07992.9 EXF74795.1 - 1.1e-26 93.9 0.2 2.1e-26 93.0 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF74795.1 - 6.5e-16 58.5 3.5 5.5e-15 55.5 0.2 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Rieske_2 PF13806.1 EXF74795.1 - 1.1e-14 53.9 0.0 9.2e-07 28.5 0.0 2.6 2 0 0 2 2 2 2 Rieske-like [2Fe-2S] domain Fer2_BFD PF04324.10 EXF74795.1 - 2.9e-13 49.6 8.6 4.1e-11 42.7 2.6 2.8 3 0 0 3 3 2 2 BFD-like [2Fe-2S] binding domain Rieske PF00355.21 EXF74795.1 - 5.6e-11 41.8 0.8 2.8e-10 39.6 0.1 2.4 2 1 0 2 2 2 1 Rieske [2Fe-2S] domain NIR_SIR_ferr PF03460.12 EXF74795.1 - 4.7e-08 32.5 0.0 9.9e-08 31.4 0.0 1.6 1 0 0 1 1 1 1 Nitrite/Sulfite reductase ferredoxin-like half domain Pyr_redox_3 PF13738.1 EXF74795.1 - 1.4e-06 28.5 0.0 0.0021 18.1 0.0 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF74795.1 - 0.012 15.4 0.5 2 8.1 0.0 3.3 3 1 1 4 4 4 0 FAD-NAD(P)-binding Amino_oxidase PF01593.19 EXF74795.1 - 0.1 11.6 0.1 0.26 10.3 0.0 1.6 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase GIDA PF01134.17 EXF74795.1 - 0.1 11.4 0.9 21 3.8 0.0 3.0 2 1 1 3 3 3 0 Glucose inhibited division protein A Fungal_trans_2 PF11951.3 EXF74796.1 - 3.2e-09 35.8 0.9 4.8e-09 35.3 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF74796.1 - 1.1e-08 34.7 10.2 2.5e-08 33.6 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EXF74797.1 - 1.3e-25 89.8 7.0 1.6e-25 89.6 4.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter CsbD PF05532.7 EXF74798.1 - 6.6e-08 32.1 7.9 0.0002 20.9 0.4 2.2 1 1 1 2 2 2 2 CsbD-like Aminotran_1_2 PF00155.16 EXF74801.1 - 5.8e-26 91.2 0.0 1.9e-18 66.5 0.0 3.4 3 1 0 3 3 3 2 Aminotransferase class I and II OKR_DC_1 PF01276.15 EXF74801.1 - 0.0075 14.8 0.0 0.011 14.2 0.0 1.2 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain p450 PF00067.17 EXF74802.1 - 2.8e-69 233.8 0.0 3.8e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EXF74802.1 - 7.6e-28 97.4 0.0 1.5e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EXF74802.1 - 3.1e-19 69.4 0.0 6.4e-19 68.3 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EXF74802.1 - 4.4e-10 40.0 0.0 9.4e-10 39.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EXF74802.1 - 0.0014 18.6 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin domain FAD_binding_6 PF00970.19 EXF74802.1 - 0.15 12.1 0.0 0.5 10.5 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Oxidored_FMN PF00724.15 EXF74803.1 - 3.2e-59 200.6 0.0 3.9e-52 177.3 0.0 2.2 2 1 0 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family AroM PF07302.6 EXF74803.1 - 0.028 13.7 0.0 0.053 12.8 0.0 1.4 1 0 0 1 1 1 0 AroM protein PALP PF00291.20 EXF74804.1 - 4.1e-26 91.9 0.0 8.7e-26 90.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.15 EXF74804.1 - 5.5e-10 39.5 0.0 2.6e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain MFS_1 PF07690.11 EXF74805.1 - 3.4e-50 170.7 58.4 1.5e-40 139.0 28.6 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF74805.1 - 1.5e-19 69.6 22.8 2e-19 69.2 15.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EXF74805.1 - 1.4e-18 66.6 5.1 1.4e-18 66.6 3.5 4.0 3 1 1 4 4 4 1 Sugar (and other) transporter DUF3357 PF11837.3 EXF74805.1 - 0.024 14.5 0.4 0.21 11.4 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) Sdh_cyt PF01127.17 EXF74807.1 - 6.7e-16 58.2 6.2 8.7e-16 57.8 4.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF1546 PF07571.8 EXF74808.1 - 7.9e-28 96.4 0.0 1.6e-27 95.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 EXF74808.1 - 4.9e-22 77.6 0.0 1.3e-21 76.3 0.0 1.7 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EXF74808.1 - 0.00055 20.0 0.1 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EXF74808.1 - 0.0037 17.2 0.0 0.013 15.5 0.0 1.9 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EXF74808.1 - 0.041 13.6 0.0 0.095 12.4 0.0 1.6 1 0 0 1 1 1 0 Bromodomain associated Aldo_ket_red PF00248.16 EXF74809.1 - 3.9e-65 219.4 0.0 4.8e-65 219.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Methyltransf_23 PF13489.1 EXF74810.1 - 7.5e-25 87.5 0.1 1.1e-24 86.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF74810.1 - 1.6e-09 37.5 0.0 4.8e-09 35.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF74810.1 - 8.4e-09 36.0 0.0 7.1e-08 33.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF74810.1 - 1.4e-08 35.0 0.0 1.1e-07 32.2 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF74810.1 - 1.5e-07 31.7 0.0 3e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF74810.1 - 1.5e-05 25.2 0.0 8.8e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EXF74810.1 - 0.0018 17.4 0.0 0.0029 16.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EXF74810.1 - 0.0022 18.0 0.0 0.0062 16.5 0.0 1.8 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 EXF74810.1 - 0.003 16.6 0.0 0.0066 15.5 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EXF74810.1 - 0.0053 16.7 0.0 0.01 15.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EXF74810.1 - 0.0094 15.4 0.0 0.034 13.6 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 EXF74810.1 - 0.038 13.3 0.0 0.077 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 EXF74810.1 - 0.12 11.4 0.0 1.2 8.2 0.0 2.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DJ-1_PfpI PF01965.19 EXF74811.1 - 5.5e-24 84.3 0.1 9.7e-24 83.4 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EXF74811.1 - 7e-12 44.6 0.0 1.9e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DUF4066 PF13278.1 EXF74811.1 - 0.0079 15.4 0.0 0.018 14.3 0.0 1.5 1 1 0 1 1 1 1 Putative amidotransferase GATase PF00117.23 EXF74811.1 - 0.057 12.8 0.0 0.091 12.1 0.0 1.4 1 1 0 1 1 1 0 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EXF74811.1 - 0.063 12.7 0.0 0.12 11.7 0.0 1.5 2 0 0 2 2 2 0 Peptidase C26 GATase_3 PF07685.9 EXF74811.1 - 0.095 12.2 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain PLU-1 PF08429.6 EXF74812.1 - 1.8e-98 329.5 15.5 3.2e-96 322.1 10.7 2.2 2 0 0 2 2 2 2 PLU-1-like protein JmjC PF02373.17 EXF74812.1 - 1.7e-43 147.5 0.2 4e-43 146.2 0.1 1.7 1 0 0 1 1 1 1 JmjC domain, hydroxylase ARID PF01388.16 EXF74812.1 - 2.8e-26 91.1 0.2 1.2e-25 89.1 0.0 2.3 2 0 0 2 2 2 1 ARID/BRIGHT DNA binding domain PHD PF00628.24 EXF74812.1 - 7.9e-19 67.0 32.5 4.4e-10 39.0 5.2 3.8 3 0 0 3 3 3 2 PHD-finger JmjN PF02375.12 EXF74812.1 - 1.4e-14 53.3 0.7 3.1e-14 52.1 0.5 1.7 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 EXF74812.1 - 1.2e-12 47.7 5.1 2.9e-12 46.4 3.5 1.7 1 0 0 1 1 1 1 C5HC2 zinc finger zf-PHD-like PF15446.1 EXF74812.1 - 0.0027 16.9 8.9 0.02 14.1 1.2 2.8 2 0 0 2 2 2 2 PHD/FYVE-zinc-finger like domain C1_1 PF00130.17 EXF74812.1 - 0.97 9.2 22.5 0.22 11.2 0.4 3.5 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.1 EXF74812.1 - 1.5 8.7 21.1 5.3 6.9 5.1 2.8 2 0 0 2 2 2 0 Ring finger domain PHD_2 PF13831.1 EXF74812.1 - 6.8 6.1 17.9 0.018 14.3 1.4 3.1 3 0 0 3 3 3 0 PHD-finger GIY-YIG PF01541.19 EXF74813.1 - 2.3e-08 34.2 0.0 4.2e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 GIY-YIG catalytic domain zf-HC5HC2H PF13771.1 EXF74813.1 - 0.00038 20.5 2.4 0.00073 19.6 1.7 1.4 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EXF74813.1 - 0.00048 20.1 1.3 0.00081 19.3 0.9 1.3 1 0 0 1 1 1 1 PHD-zinc-finger like domain FANCL_C PF11793.3 EXF74813.1 - 0.00061 19.7 3.0 0.001 18.9 2.1 1.3 1 0 0 1 1 1 1 FANCL C-terminal domain Prok-RING_1 PF14446.1 EXF74813.1 - 0.038 13.7 5.6 0.13 11.9 2.4 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_2 PF13639.1 EXF74813.1 - 0.092 12.5 8.2 0.17 11.7 5.7 1.5 1 0 0 1 1 1 0 Ring finger domain T5orf172 PF10544.4 EXF74813.1 - 0.098 13.0 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 T5orf172 domain zf-RING-like PF08746.6 EXF74813.1 - 0.099 12.6 8.3 0.3 11.1 5.8 1.8 1 1 0 1 1 1 0 RING-like domain PHD PF00628.24 EXF74813.1 - 5.7 6.7 7.6 9.3 6.0 5.3 1.4 1 0 0 1 1 1 0 PHD-finger Pkinase PF00069.20 EXF74815.1 - 1.8e-30 105.9 0.0 2.3e-30 105.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF74815.1 - 2.5e-14 52.9 0.0 4.2e-14 52.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EXF74815.1 - 0.1 11.3 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3449 PF11931.3 EXF74816.1 - 1.1e-73 246.9 0.5 4.6e-73 244.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 EXF74816.1 - 4.8e-11 41.9 0.1 1e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 EXF74816.1 - 7.7e-09 35.4 2.1 4.8e-07 29.7 0.4 2.4 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EXF74816.1 - 1.7e-07 31.2 0.7 1.7e-07 31.2 0.5 2.6 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EXF74816.1 - 0.0008 19.4 1.6 0.011 15.7 0.4 2.6 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) DUF951 PF06107.6 EXF74816.1 - 0.06 12.8 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF951) zf-C2H2_4 PF13894.1 EXF74816.1 - 0.08 13.3 3.3 2.1 8.8 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-U1 PF06220.7 EXF74816.1 - 0.11 12.0 0.4 0.31 10.6 0.3 1.8 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2 PF00096.21 EXF74816.1 - 0.33 11.3 5.8 0.74 10.2 0.6 2.6 2 0 0 2 2 2 0 Zinc finger, C2H2 type DEAD PF00270.24 EXF74817.1 - 2.4e-40 137.7 0.3 6.3e-40 136.4 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF74817.1 - 4.4e-29 100.1 0.2 9.1e-29 99.1 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_30 PF13604.1 EXF74817.1 - 0.014 15.0 0.6 0.032 13.8 0.4 1.6 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EXF74817.1 - 0.019 14.6 0.2 0.049 13.4 0.1 1.7 1 0 0 1 1 1 0 Part of AAA domain ResIII PF04851.10 EXF74817.1 - 0.036 13.9 0.1 0.079 12.7 0.1 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EXF74817.1 - 0.045 13.5 0.2 0.15 11.8 0.0 2.0 2 1 0 2 2 2 0 Flavivirus DEAD domain AAA_22 PF13401.1 EXF74817.1 - 0.096 12.8 0.7 0.43 10.7 0.5 2.0 1 1 0 1 1 1 0 AAA domain FtsH_ext PF06480.10 EXF74818.1 - 1.7 8.8 4.6 0.44 10.7 0.7 1.8 2 0 0 2 2 2 0 FtsH Extracellular TauD PF02668.11 EXF74819.1 - 7.5e-44 150.3 0.1 1e-43 149.8 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Abhydrolase_6 PF12697.2 EXF74822.1 - 3.5e-32 112.1 0.2 5e-32 111.6 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF74822.1 - 5.6e-14 52.2 0.0 6.2e-13 48.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF74822.1 - 2.8e-12 46.6 0.0 4.1e-11 42.8 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EXF74822.1 - 0.00046 19.9 0.0 0.00077 19.2 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase PGAP1 PF07819.8 EXF74822.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein Peptidase_S28 PF05577.7 EXF74823.1 - 1.3e-52 178.9 0.0 6.9e-52 176.4 0.0 1.8 1 1 0 1 1 1 1 Serine carboxypeptidase S28 GMC_oxred_N PF00732.14 EXF74824.1 - 8.7e-52 176.1 0.0 1.2e-51 175.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF74824.1 - 1.8e-26 93.1 0.5 3.6e-26 92.1 0.3 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EXF74824.1 - 3.5e-05 22.8 0.1 0.021 13.6 0.0 2.4 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 EXF74824.1 - 4.7e-05 22.4 1.9 0.00075 18.4 1.3 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF74824.1 - 0.0037 17.2 0.0 0.0093 15.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EXF74824.1 - 0.013 15.5 0.1 3 7.8 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF74824.1 - 0.021 14.7 0.0 1.8 8.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF74824.1 - 0.16 11.0 0.1 0.16 11.0 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Malate_synthase PF01274.17 EXF74827.1 - 5e-215 714.4 0.0 6.3e-215 714.1 0.0 1.1 1 0 0 1 1 1 1 Malate synthase Fungal_trans PF04082.13 EXF74827.1 - 4.3e-14 52.0 0.0 1.7e-13 50.0 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain HpcH_HpaI PF03328.9 EXF74827.1 - 0.0089 14.9 0.0 0.018 13.9 0.0 1.5 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family SOUL PF04832.7 EXF74827.1 - 0.18 11.3 0.0 0.6 9.6 0.0 1.8 2 0 0 2 2 2 0 SOUL heme-binding protein GerA PF03323.8 EXF74828.1 - 0.052 11.6 0.0 0.074 11.1 0.0 1.1 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein TpcC PF12642.2 EXF74828.1 - 0.082 12.4 0.3 1.1 8.7 0.0 2.0 2 0 0 2 2 2 0 Conjugative transposon protein TcpC Hydant_A_N PF05378.8 EXF74828.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region DUF3176 PF11374.3 EXF74829.1 - 6.9e-33 112.8 1.6 6.9e-33 112.8 1.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) p450 PF00067.17 EXF74831.1 - 1.7e-53 181.8 0.0 3.3e-53 180.8 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_M14 PF00246.19 EXF74832.1 - 1.1e-25 90.8 5.4 2.5e-25 89.6 3.7 1.6 1 1 0 1 1 1 1 Zinc carboxypeptidase KGG PF10685.4 EXF74832.1 - 0.36 10.8 2.1 0.7 9.9 1.4 1.4 1 0 0 1 1 1 0 Stress-induced bacterial acidophilic repeat motif SRP54 PF00448.17 EXF74833.1 - 7.8e-76 253.8 2.9 1e-75 253.5 1.1 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EXF74833.1 - 7.9e-25 87.1 6.4 7.9e-25 87.1 4.4 4.5 3 1 3 6 6 4 1 Signal peptide binding domain SRP54_N PF02881.14 EXF74833.1 - 9.7e-15 54.4 0.3 2.4e-14 53.1 0.2 1.7 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EXF74833.1 - 9.1e-08 31.7 0.1 2.3e-07 30.4 0.1 1.7 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EXF74833.1 - 3e-07 30.3 0.0 6.8e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EXF74833.1 - 1.8e-05 25.5 0.0 4.2e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EXF74833.1 - 2.5e-05 24.0 0.0 5.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EXF74833.1 - 0.00029 20.3 0.2 0.0009 18.6 0.2 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EXF74833.1 - 0.00066 19.6 0.0 0.14 12.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.15 EXF74833.1 - 0.002 17.8 0.0 0.0042 16.7 0.0 1.5 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_22 PF13401.1 EXF74833.1 - 0.002 18.2 0.0 0.0068 16.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EXF74833.1 - 0.0036 17.3 0.1 0.01 15.8 0.0 1.9 1 1 1 2 2 2 1 AAA ATPase domain Thymidylate_kin PF02223.12 EXF74833.1 - 0.0051 16.2 0.3 0.014 14.7 0.0 1.9 2 0 0 2 2 1 1 Thymidylate kinase SRPRB PF09439.5 EXF74833.1 - 0.0053 15.9 0.6 2.2 7.4 0.6 3.2 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 EXF74833.1 - 0.0066 16.0 0.2 0.037 13.5 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 EXF74833.1 - 0.0074 16.5 0.0 0.019 15.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EXF74833.1 - 0.0088 15.1 0.0 0.02 13.9 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin TrwB_AAD_bind PF10412.4 EXF74833.1 - 0.021 13.4 0.0 0.045 12.3 0.0 1.5 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_28 PF13521.1 EXF74833.1 - 0.035 14.0 0.0 0.074 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EXF74833.1 - 0.058 12.8 0.1 0.11 11.9 0.1 1.6 1 1 0 1 1 1 0 AAA-like domain 6PF2K PF01591.13 EXF74833.1 - 0.069 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 6-phosphofructo-2-kinase AAA PF00004.24 EXF74833.1 - 0.081 13.1 0.2 0.23 11.6 0.1 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF3786 PF12654.2 EXF74833.1 - 0.084 12.1 0.7 3.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3786) AAA_19 PF13245.1 EXF74833.1 - 0.084 12.6 0.1 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain Arf PF00025.16 EXF74833.1 - 0.087 12.0 0.1 0.32 10.2 0.0 2.0 2 0 0 2 2 2 0 ADP-ribosylation factor family PAP2 PF01569.16 EXF74834.1 - 3.9e-21 75.0 4.6 8.3e-21 74.0 3.2 1.6 1 0 0 1 1 1 1 PAP2 superfamily TIP_N PF12457.3 EXF74835.1 - 0.0029 17.6 0.5 0.0039 17.2 0.3 1.2 1 0 0 1 1 1 1 Tuftelin interacting protein N terminal DUF3915 PF13054.1 EXF74835.1 - 0.062 13.2 0.3 0.077 12.9 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) NinF PF05810.7 EXF74835.1 - 0.079 12.7 1.0 0.11 12.2 0.7 1.2 1 0 0 1 1 1 0 NinF protein Ecl1 PF12855.2 EXF74835.1 - 0.12 11.6 3.2 0.23 10.7 2.2 1.4 1 0 0 1 1 1 0 Life-span regulatory factor PLATZ PF04640.9 EXF74835.1 - 0.25 11.5 0.6 0.25 11.5 0.4 1.6 2 0 0 2 2 2 0 PLATZ transcription factor MFS_1 PF07690.11 EXF74836.1 - 1.2e-43 149.1 36.5 2.9e-37 128.1 17.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Lactamase_B PF00753.22 EXF74838.1 - 2.7e-06 27.1 2.8 7.7e-06 25.6 2.0 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EXF74838.1 - 5.8e-05 22.7 0.0 9.4e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain E1-E2_ATPase PF00122.15 EXF74839.1 - 5.9e-67 225.0 4.0 1.4e-66 223.8 2.8 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EXF74839.1 - 1.3e-34 119.2 6.0 1.3e-34 119.2 4.2 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EXF74839.1 - 2.9e-29 103.0 0.5 7.6e-24 85.3 0.3 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EXF74839.1 - 2e-19 69.3 0.0 4.3e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EXF74839.1 - 1.7e-14 53.0 0.0 5.2e-14 51.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EXF74839.1 - 3.2e-11 43.7 0.1 8.1e-11 42.4 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EXF74839.1 - 2.4e-06 27.3 0.5 0.00028 20.5 0.4 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ADH_zinc_N PF00107.21 EXF74841.1 - 1.8e-12 46.9 0.1 1.9e-11 43.6 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF74841.1 - 1.7e-05 24.5 0.0 3.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EXF74841.1 - 0.0054 16.3 0.0 0.0092 15.5 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.20 EXF74842.1 - 3.5e-09 36.7 0.0 1.1e-08 35.1 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF74842.1 - 6.4e-06 26.1 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF74842.1 - 0.0088 15.7 0.4 0.028 14.0 0.1 1.9 2 0 0 2 2 2 1 KR domain Glyco_trans_4_4 PF13579.1 EXF74842.1 - 0.14 12.2 0.0 1.4 9.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain Zn_clus PF00172.13 EXF74843.1 - 1.1e-06 28.4 9.7 2e-06 27.6 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MgpC PF05220.7 EXF74843.1 - 0.091 11.8 0.3 0.15 11.1 0.2 1.3 1 0 0 1 1 1 0 MgpC protein precursor Sporozoite_P67 PF05642.6 EXF74843.1 - 0.35 8.6 0.9 0.49 8.1 0.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DUF3425 PF11905.3 EXF74844.1 - 1.4e-28 99.4 0.2 2e-28 98.9 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Cytochrome-c551 PF10643.4 EXF74845.1 - 0.21 10.8 3.9 0.42 9.8 2.7 1.4 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 PARP PF00644.15 EXF74846.1 - 4.9e-61 205.7 0.5 1.2e-60 204.5 0.0 1.9 2 1 1 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EXF74846.1 - 9.9e-42 141.7 0.8 1.2e-41 141.4 0.1 1.5 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 EXF74846.1 - 7.2e-22 77.1 0.2 7.2e-22 77.1 0.2 2.4 3 0 0 3 3 3 1 WGR domain PTCB-BRCT PF12738.2 EXF74846.1 - 1.5e-11 43.9 0.4 3.9e-11 42.6 0.3 1.8 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EXF74846.1 - 7.6e-10 38.8 0.0 1.6e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain CCD PF07860.6 EXF74846.1 - 0.76 9.2 6.3 1.8 8.0 0.1 3.0 2 0 0 2 2 2 0 WisP family C-Terminal Region CAF1A PF12253.3 EXF74846.1 - 4.9 7.3 11.7 0.75 9.9 4.8 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 subunit A F-box PF00646.28 EXF74847.1 - 0.00031 20.3 0.2 0.00073 19.1 0.2 1.6 1 0 0 1 1 1 1 F-box domain Amidohydro_2 PF04909.9 EXF74847.1 - 0.009 15.5 0.1 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase F-box-like PF12937.2 EXF74847.1 - 0.0092 15.6 0.1 0.017 14.8 0.1 1.4 1 0 0 1 1 1 1 F-box-like DJ-1_PfpI PF01965.19 EXF74848.1 - 5.9e-08 32.2 0.0 9.2e-08 31.6 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family p450 PF00067.17 EXF74850.1 - 3.3e-44 151.1 0.0 4.6e-44 150.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 YjbE PF11106.3 EXF74852.1 - 0.074 13.0 0.9 0.088 12.7 0.6 1.3 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE AMMECR1 PF01871.12 EXF74853.1 - 2.6e-46 156.8 0.0 1.2e-45 154.7 0.0 1.8 2 0 0 2 2 2 1 AMMECR1 Crystall PF00030.14 EXF74853.1 - 0.097 12.5 0.1 0.23 11.3 0.1 1.6 1 0 0 1 1 1 0 Beta/Gamma crystallin Mid2 PF04478.7 EXF74854.1 - 0.11 11.9 0.1 0.2 11.0 0.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF2407_C PF13373.1 EXF74854.1 - 0.17 11.8 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 DUF2407 C-terminal domain SET PF00856.23 EXF74855.1 - 7.7e-08 32.8 0.0 2.1e-07 31.4 0.0 1.7 1 1 0 1 1 1 1 SET domain Oxysterol_BP PF01237.13 EXF74855.1 - 0.082 11.3 0.0 0.13 10.7 0.0 1.2 1 0 0 1 1 1 0 Oxysterol-binding protein Cnd3 PF12719.2 EXF74855.1 - 0.17 10.8 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain Methyltransf_2 PF00891.13 EXF74857.1 - 3.1e-28 98.6 0.0 4.6e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase SPT16 PF08644.6 EXF74857.1 - 0.17 11.6 0.0 0.29 10.9 0.0 1.3 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Aldolase_II PF00596.16 EXF74859.1 - 8.7e-12 45.0 0.0 1.2e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain GTF2I PF02946.9 EXF74859.1 - 0.068 13.0 0.0 3.9 7.3 0.0 2.1 1 1 1 2 2 2 0 GTF2I-like repeat Cutinase PF01083.17 EXF74860.1 - 1.5e-31 109.5 0.2 5.6e-30 104.3 0.2 2.0 1 1 0 1 1 1 1 Cutinase Abhydrolase_1 PF00561.15 EXF74860.1 - 0.00054 19.5 0.1 0.00061 19.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.3 EXF74860.1 - 0.0043 16.4 0.0 0.0056 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 EXF74860.1 - 0.0082 15.8 0.1 0.011 15.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family VirJ PF06057.6 EXF74860.1 - 0.0084 15.9 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_6 PF12697.2 EXF74860.1 - 0.02 14.8 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 EXF74860.1 - 0.022 14.3 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.15 EXF74860.1 - 0.029 14.5 0.1 0.037 14.2 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain PE-PPE PF08237.6 EXF74860.1 - 0.056 12.8 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain Cutinase PF01083.17 EXF74861.1 - 1.6e-43 148.5 0.4 1.9e-43 148.2 0.3 1.1 1 0 0 1 1 1 1 Cutinase DUF2974 PF11187.3 EXF74861.1 - 0.033 13.5 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) PE-PPE PF08237.6 EXF74861.1 - 0.062 12.7 0.1 0.14 11.5 0.0 1.5 1 1 0 1 1 1 0 PE-PPE domain Abhydrolase_2 PF02230.11 EXF74861.1 - 0.072 12.5 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase R_equi_Vir PF05526.6 EXF74862.1 - 0.00017 21.2 0.4 0.00017 21.2 0.3 2.1 1 1 1 2 2 2 1 Rhodococcus equi virulence-associated protein eIF2A PF08662.6 EXF74865.1 - 1.7e-77 259.5 0.0 1.1e-76 256.8 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EXF74865.1 - 0.00014 21.5 1.7 2.8 7.9 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat CDV3 PF15359.1 EXF74865.1 - 0.0031 17.5 0.3 0.0031 17.5 0.2 2.7 4 0 0 4 4 4 1 Carnitine deficiency-associated protein 3 RPAP1_C PF08620.5 EXF74867.1 - 3.5e-29 100.4 0.0 7.1e-29 99.4 0.0 1.5 1 0 0 1 1 1 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EXF74867.1 - 5.7e-16 57.8 6.9 5.7e-16 57.8 4.8 1.7 2 0 0 2 2 2 1 RPAP1-like, N-terminal HUN PF08729.5 EXF74868.1 - 2.7e-13 49.5 1.2 6e-13 48.4 0.8 1.6 1 0 0 1 1 1 1 HPC2 and ubinuclein domain SURF6 PF04935.7 EXF74869.1 - 1.3e-47 161.8 35.8 1.3e-47 161.8 24.8 4.3 2 1 1 4 4 4 1 Surfeit locus protein 6 RRP14 PF15459.1 EXF74869.1 - 2.7e-20 72.2 1.1 2.7e-20 72.2 0.8 7.5 5 1 2 7 7 7 1 60S ribosome biogenesis protein Rrp14 GPP34 PF05719.6 EXF74870.1 - 4e-66 222.9 0.3 5.3e-66 222.6 0.2 1.1 1 0 0 1 1 1 1 Golgi phosphoprotein 3 (GPP34) Aldo_ket_red PF00248.16 EXF74871.1 - 7.5e-60 202.1 0.0 9.6e-60 201.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sugar_tr PF00083.19 EXF74873.1 - 1.8e-75 254.2 20.3 2.2e-75 253.9 14.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF74873.1 - 1.5e-18 66.6 25.6 2.5e-18 65.9 17.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EXF74873.1 - 7.9e-08 31.1 18.8 2e-06 26.5 0.7 3.0 2 1 1 3 3 3 2 MFS/sugar transport protein ATG22 PF11700.3 EXF74873.1 - 0.13 10.6 16.0 0.11 10.9 4.5 2.3 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like Bromodomain PF00439.20 EXF74875.1 - 1.4e-18 66.5 0.2 1.4e-18 66.5 0.1 1.9 2 0 0 2 2 2 1 Bromodomain Bromo_TP PF07524.8 EXF74875.1 - 5.9e-08 32.3 0.0 1.4e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated VanZ PF04892.7 EXF74876.1 - 9.3e-12 45.0 3.7 1.2e-11 44.6 2.6 1.2 1 0 0 1 1 1 1 VanZ like family DUF4401 PF14351.1 EXF74876.1 - 0.019 13.9 1.0 0.025 13.5 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) DUF2678 PF10856.3 EXF74876.1 - 0.034 13.8 0.6 0.12 12.0 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2678) UPF0542 PF15086.1 EXF74876.1 - 0.078 12.6 0.1 1.8 8.3 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 NAD_binding_6 PF08030.7 EXF74877.1 - 1.6e-15 57.3 0.0 2.3e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EXF74877.1 - 1.8e-15 57.1 10.7 4.3e-15 55.8 7.4 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EXF74877.1 - 2.1e-07 30.7 0.0 1.9e-06 27.6 0.0 2.2 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EXF74877.1 - 1.6e-05 25.3 0.0 0.027 15.0 0.0 2.4 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain COX6C PF02937.10 EXF74877.1 - 1.6 8.6 3.8 1.4 8.8 0.4 2.3 1 1 0 2 2 2 0 Cytochrome c oxidase subunit VIc CorA PF01544.13 EXF74878.1 - 8.6e-05 21.6 2.5 0.00027 20.0 1.7 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Peptidase_S64 PF08192.6 EXF74879.1 - 4.5e-07 28.6 0.2 0.00033 19.1 0.1 2.2 2 0 0 2 2 2 2 Peptidase family S64 Trypsin_2 PF13365.1 EXF74879.1 - 0.0016 18.3 0.0 0.0052 16.7 0.0 2.0 1 1 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_S32 PF05579.8 EXF74879.1 - 0.0018 17.3 0.4 0.0027 16.7 0.3 1.2 1 0 0 1 1 1 1 Equine arteritis virus serine endopeptidase S32 Trypsin PF00089.21 EXF74879.1 - 0.045 13.3 0.2 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 Trypsin Peptidase_S3 PF00944.14 EXF74879.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Alphavirus core protein Ank_2 PF12796.2 EXF74881.1 - 1.3e-37 127.9 0.0 4.5e-11 42.9 0.0 6.6 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EXF74881.1 - 8e-29 97.9 0.4 9.3e-06 25.2 0.0 9.5 9 1 0 9 9 9 5 Ankyrin repeat Ank_4 PF13637.1 EXF74881.1 - 1.5e-23 82.7 0.1 0.0012 19.2 0.0 7.6 7 1 2 9 9 9 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF74881.1 - 2.4e-23 81.6 5.3 1.1e-05 25.4 0.0 8.6 9 0 0 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF74881.1 - 4.7e-21 72.7 0.0 0.0051 16.9 0.0 9.7 9 0 0 9 9 9 4 Ankyrin repeat NACHT PF05729.7 EXF74881.1 - 4.4e-05 23.1 0.0 0.00015 21.4 0.0 2.0 1 1 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EXF74881.1 - 0.00058 20.0 0.0 0.0019 18.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EXF74881.1 - 0.0084 16.1 0.1 0.079 12.9 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EXF74881.1 - 0.077 13.3 0.0 3.5 7.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain Ribonuc_L-PSP PF01042.16 EXF74882.1 - 3.4e-36 123.6 0.0 3.9e-36 123.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP RRM_1 PF00076.17 EXF74883.1 - 7.2e-11 41.5 0.0 1.3e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF74883.1 - 2.7e-08 33.6 0.0 6.1e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF74883.1 - 1.5e-07 31.1 0.0 2.5e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EXF74883.1 - 0.026 14.3 0.9 0.085 12.7 0.0 2.1 2 0 0 2 2 2 0 RNA binding motif RF-1 PF00472.15 EXF74884.1 - 8.2e-12 44.9 2.1 1.5e-11 44.1 1.4 1.4 1 1 0 1 1 1 1 RF-1 domain Pkinase PF00069.20 EXF74885.1 - 8.7e-70 234.8 0.0 1.1e-69 234.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF74885.1 - 5.7e-30 104.2 0.0 7.6e-30 103.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF74885.1 - 5.6e-07 28.7 0.0 7.7e-07 28.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EXF74885.1 - 0.00029 20.6 0.1 0.00048 19.9 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EXF74885.1 - 0.0011 18.1 0.0 0.002 17.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EXF74885.1 - 0.049 12.9 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Fungal_trans_2 PF11951.3 EXF74886.1 - 5.6e-06 25.2 0.4 8.3e-06 24.6 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain PQQ_3 PF13570.1 EXF74887.1 - 0.0088 16.2 7.7 0.066 13.5 0.1 4.7 4 1 0 4 4 4 1 PQQ-like domain DUF2416 PF10315.4 EXF74887.1 - 0.044 14.0 0.2 0.14 12.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2416) PQQ PF01011.16 EXF74887.1 - 0.34 10.5 2.2 3.3 7.4 0.0 3.4 3 0 0 3 3 3 0 PQQ enzyme repeat CLN3 PF02487.12 EXF74889.1 - 2.4e-19 69.4 3.0 3.1e-19 69.0 2.1 1.1 1 0 0 1 1 1 1 CLN3 protein Apolipoprotein PF01442.13 EXF74890.1 - 0.095 12.1 0.0 1.2 8.5 0.0 2.3 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Myb_CC_LHEQLE PF14379.1 EXF74890.1 - 0.1 12.1 0.1 29 4.3 0.0 3.2 3 0 0 3 3 3 0 MYB-CC type transfactor, LHEQLE motif DUF1111 PF06537.6 EXF74891.1 - 0.15 10.2 0.0 0.22 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1111) 2-oxoacid_dh PF00198.18 EXF74892.1 - 0.039 13.2 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) DASH_Spc34 PF08657.5 EXF74895.1 - 1.3e-50 172.4 0.0 3.5e-50 171.0 0.0 1.6 1 1 0 1 1 1 1 DASH complex subunit Spc34 SlyX PF04102.7 EXF74895.1 - 0.13 12.7 3.6 1.6 9.1 0.1 2.7 2 0 0 2 2 2 0 SlyX V_ATPase_I PF01496.14 EXF74895.1 - 0.37 8.5 3.4 0.45 8.3 2.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YL1 PF05764.8 EXF74895.1 - 6 6.4 17.3 2.2 7.8 10.1 1.6 2 0 0 2 2 2 0 YL1 nuclear protein Spt5_N PF11942.3 EXF74895.1 - 6.3 7.4 19.4 4.7 7.8 10.6 2.3 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal NOA36 PF06524.7 EXF74895.1 - 6.7 5.8 6.2 9.5 5.3 4.3 1.1 1 0 0 1 1 1 0 NOA36 protein DSBA PF01323.15 EXF74896.1 - 5.1e-33 114.2 0.0 5.8e-33 114.0 0.0 1.0 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_3 PF13192.1 EXF74896.1 - 0.00021 21.0 0.1 0.011 15.4 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin domain Thioredoxin_2 PF13098.1 EXF74896.1 - 0.0022 18.1 0.0 0.33 11.1 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_4 PF13462.1 EXF74896.1 - 0.01 15.8 0.0 0.043 13.8 0.0 1.9 2 1 0 2 2 2 0 Thioredoxin PEP_mutase PF13714.1 EXF74896.1 - 0.057 12.6 0.2 0.09 11.9 0.1 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate phosphomutase zf-RING_2 PF13639.1 EXF74897.1 - 1.1e-05 25.1 13.6 1.9e-05 24.4 9.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EXF74897.1 - 2.9e-05 24.0 11.0 6.9e-05 22.8 7.6 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EXF74897.1 - 0.0001 21.8 10.2 0.00017 21.1 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EXF74897.1 - 0.0003 20.7 9.4 0.00048 20.0 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EXF74897.1 - 0.00037 20.0 9.3 0.00055 19.5 6.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EXF74897.1 - 1.4 8.8 6.4 3.6 7.5 4.5 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Drc1-Sld2 PF11719.3 EXF74898.1 - 1.9e-97 327.1 28.5 2.1e-97 326.9 19.7 1.0 1 0 0 1 1 1 1 DNA replication and checkpoint protein FMO-like PF00743.14 EXF74900.1 - 2.7e-30 105.0 0.0 4.2e-15 54.9 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EXF74900.1 - 4.4e-18 66.0 0.0 1.4e-12 48.1 0.0 2.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF74900.1 - 1.8e-12 47.3 0.2 4.7e-06 26.4 0.0 3.4 3 0 0 3 3 3 3 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EXF74900.1 - 1.8e-10 41.0 0.0 2e-06 27.8 0.0 3.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF74900.1 - 1.1e-09 37.7 0.2 2.5e-07 29.9 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EXF74900.1 - 0.00031 20.6 0.0 0.0011 18.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EXF74900.1 - 0.0037 16.3 0.3 0.021 13.9 0.0 2.0 2 0 0 2 2 2 1 Thi4 family DAO PF01266.19 EXF74900.1 - 0.0085 15.0 2.9 1.1 8.0 0.6 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Semialdhyde_dh PF01118.19 EXF74900.1 - 0.05 13.9 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain MFS_1 PF07690.11 EXF74901.1 - 2.7e-35 121.7 20.6 2.7e-35 121.7 14.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Cation_ATPase_C PF00689.16 EXF74901.1 - 0.49 9.9 0.0 0.49 9.9 0.0 3.6 4 1 0 4 4 4 0 Cation transporting ATPase, C-terminus CbtA PF09490.5 EXF74901.1 - 0.62 9.3 7.9 0.57 9.4 0.4 3.4 3 1 1 4 4 4 0 Probable cobalt transporter subunit (CbtA) Alk_phosphatase PF00245.15 EXF74902.1 - 9.7e-84 281.4 0.0 1.2e-83 281.2 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Macoilin PF09726.4 EXF74903.1 - 5.1 5.2 7.1 10 4.2 4.9 1.4 1 0 0 1 1 1 0 Transmembrane protein DNA_methylase PF00145.12 EXF74904.1 - 2.8e-35 122.0 0.0 5.4e-35 121.0 0.0 1.4 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase BAH PF01426.13 EXF74904.1 - 5.9e-07 29.2 0.0 0.00058 19.5 0.1 2.5 2 0 0 2 2 2 2 BAH domain DUF155 PF02582.9 EXF74905.1 - 1e-40 139.4 0.0 1.4e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 HTH_39 PF14090.1 EXF74907.1 - 0.0063 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain DUF1777 PF08648.7 EXF74907.1 - 0.087 12.5 11.6 0.13 11.9 8.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) Atrophin-1 PF03154.10 EXF74907.1 - 1.1 7.2 8.9 1.5 6.9 6.1 1.1 1 0 0 1 1 1 0 Atrophin-1 family Asp PF00026.18 EXF74910.1 - 4.4e-109 364.5 0.1 5.6e-109 364.2 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EXF74910.1 - 2.6e-10 40.5 0.0 5.8e-10 39.3 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EXF74910.1 - 5.3e-06 26.8 0.1 0.053 14.0 0.0 3.0 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EXF74910.1 - 4e-05 23.2 0.0 0.00032 20.2 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EXF74910.1 - 0.0065 16.2 0.0 6.7 6.6 0.0 3.1 2 1 1 3 3 3 2 gag-polyprotein putative aspartyl protease Alpha-amylase_C PF02806.13 EXF74910.1 - 0.039 14.0 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain SHMT PF00464.14 EXF74911.1 - 1.2e-207 689.0 0.0 1.4e-207 688.8 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 EXF74911.1 - 0.019 13.6 0.0 0.03 13.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Beta_elim_lyase PF01212.16 EXF74911.1 - 0.045 12.9 0.0 0.091 11.8 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase Hce2 PF14856.1 EXF74912.1 - 1.8e-16 59.7 0.0 2.5e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Pathogen effector; putative necrosis-inducing factor AAA_16 PF13191.1 EXF74913.1 - 9.3e-07 29.0 0.0 7.7e-06 26.0 0.0 2.6 3 0 0 3 3 2 1 AAA ATPase domain NB-ARC PF00931.17 EXF74913.1 - 0.00028 19.8 0.0 0.0005 19.0 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain DUF676 PF05057.9 EXF74913.1 - 0.00035 19.9 0.4 0.00082 18.7 0.3 1.6 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EXF74913.1 - 0.0015 18.1 0.0 0.0029 17.2 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein RuvB_N PF05496.7 EXF74913.1 - 0.0056 15.7 0.0 0.016 14.2 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Abhydrolase_6 PF12697.2 EXF74913.1 - 0.0064 16.4 0.1 0.025 14.4 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF74913.1 - 0.018 14.7 0.0 0.06 13.0 0.0 1.9 1 0 0 1 1 1 0 Alpha/beta hydrolase family AAA_14 PF13173.1 EXF74913.1 - 0.045 13.6 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EXF74913.1 - 0.061 13.2 0.0 0.85 9.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EXF74913.1 - 0.073 13.3 0.0 0.56 10.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EXF74913.1 - 0.075 13.8 0.0 0.29 11.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EXF74913.1 - 0.12 12.5 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EXF74913.1 - 0.19 11.1 0.0 0.38 10.2 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 EXF74913.1 - 0.26 10.3 0.0 0.68 9.0 0.0 1.6 1 0 0 1 1 1 0 KaiC Arch_ATPase PF01637.13 EXF74913.1 - 0.36 10.4 0.0 0.66 9.6 0.0 1.4 1 0 0 1 1 1 0 Archaeal ATPase FHA PF00498.21 EXF74914.1 - 8.3e-15 54.6 0.0 1.4e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 FHA domain MIP-T3 PF10243.4 EXF74914.1 - 4.1 5.7 43.0 5.5 5.3 29.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 VHS PF00790.14 EXF74915.1 - 7.9e-46 155.1 0.1 3.3e-45 153.1 0.0 2.1 3 0 0 3 3 3 1 VHS domain GAT PF03127.9 EXF74915.1 - 5.6e-24 84.0 1.6 1.4e-23 82.7 1.1 1.7 1 0 0 1 1 1 1 GAT domain Alpha_adaptinC2 PF02883.15 EXF74915.1 - 1.6e-17 63.8 0.0 8.8e-17 61.4 0.0 2.2 2 0 0 2 2 2 1 Adaptin C-terminal domain Clathrin PF00637.15 EXF74915.1 - 0.087 12.4 0.2 0.19 11.2 0.1 1.5 1 0 0 1 1 1 0 Region in Clathrin and VPS DUF367 PF04034.8 EXF74916.1 - 7.9e-47 158.0 0.0 1.1e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EXF74916.1 - 4e-11 42.2 1.1 9.6e-11 41.0 0.7 1.7 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI GTP_EFTU PF00009.22 EXF74917.1 - 1.4e-39 135.4 1.9 5.8e-39 133.4 1.3 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EXF74917.1 - 7.4e-26 90.1 1.8 1.7e-25 88.9 1.2 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 MMR_HSR1 PF01926.18 EXF74917.1 - 5.8e-08 32.6 0.1 1.8e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase IF2_N PF04760.10 EXF74917.1 - 2.8e-07 30.0 0.0 6.1e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region Miro PF08477.8 EXF74917.1 - 3.2e-07 30.8 0.1 6.9e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D2 PF03144.20 EXF74917.1 - 1.4e-06 28.3 0.4 0.001 19.1 0.0 2.9 2 0 0 2 2 2 2 Elongation factor Tu domain 2 Arf PF00025.16 EXF74917.1 - 6.9e-05 22.1 0.0 0.00014 21.1 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.13 EXF74917.1 - 7.4e-05 22.0 0.3 0.00027 20.2 0.1 2.1 2 1 0 2 2 2 1 Ferrous iron transport protein B SRPRB PF09439.5 EXF74917.1 - 0.00026 20.2 0.1 0.00065 18.9 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EXF74917.1 - 0.002 17.5 0.1 0.0033 16.8 0.0 1.3 1 0 0 1 1 1 1 Ras family PduV-EutP PF10662.4 EXF74917.1 - 0.0034 16.8 0.1 0.0083 15.6 0.1 1.7 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.12 EXF74917.1 - 0.047 13.2 0.0 0.16 11.4 0.0 1.8 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.18 EXF74917.1 - 0.083 12.7 0.9 3 7.6 0.0 2.9 2 1 1 3 3 3 0 Dynamin family PP28 PF10252.4 EXF74919.1 - 7.9e-23 80.2 20.2 7.9e-23 80.2 14.0 3.3 2 1 1 3 3 3 2 Casein kinase substrate phosphoprotein PP28 CoA_trans PF01144.18 EXF74921.1 - 3.2e-96 320.6 1.3 4.7e-58 195.9 0.0 2.0 2 0 0 2 2 2 2 Coenzyme A transferase C-term_anchor PF13461.1 EXF74921.1 - 0.12 12.8 0.3 0.66 10.4 0.1 2.3 2 0 0 2 2 2 0 Cell-wall surface anchor repeat Nrap PF03813.9 EXF74922.1 - 0 1031.0 0.0 0 1030.8 0.0 1.0 1 0 0 1 1 1 1 Nrap protein ComFB PF10719.4 EXF74923.1 - 0.076 12.7 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 Late competence development protein ComFB DUF1918 PF08940.6 EXF74923.1 - 0.096 12.0 0.4 4.2 6.7 0.0 3.8 5 0 0 5 5 5 0 Domain of unknown function (DUF1918) Peptidase_C12 PF01088.16 EXF74924.1 - 6e-56 188.9 0.0 1.6e-55 187.5 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 BRF1 PF07741.8 EXF74924.1 - 4.1 7.7 9.1 0.16 12.1 0.2 2.4 2 1 0 2 2 2 0 Brf1-like TBP-binding domain Transglut_core2 PF13369.1 EXF74925.1 - 1.6e-18 66.6 0.0 2.7e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 EXF74925.1 - 1.8e-08 33.9 1.7 7.4e-08 32.0 0.7 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EXF74925.1 - 0.00012 21.6 0.7 0.00032 20.2 0.5 1.8 1 0 0 1 1 1 1 F-box domain YccV-like PF08755.6 EXF74925.1 - 0.0011 18.8 0.1 0.0024 17.7 0.1 1.6 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Microtub_assoc PF07989.6 EXF74926.1 - 9.6e-28 95.8 3.7 9.6e-28 95.8 2.6 14.2 7 4 11 20 20 20 1 Microtubule associated PACT_coil_coil PF10495.4 EXF74926.1 - 1.6e-11 43.9 0.8 6.6e-11 41.9 0.6 2.2 1 0 0 1 1 1 1 Pericentrin-AKAP-450 domain of centrosomal targeting protein CCDC155 PF14662.1 EXF74926.1 - 0.00016 21.3 15.7 0.00016 21.3 10.9 9.9 2 1 8 10 10 8 1 Coiled-coil region of CCDC155 AAA_13 PF13166.1 EXF74926.1 - 0.00023 19.7 159.8 0.0041 15.6 14.1 6.3 1 1 5 6 6 6 5 AAA domain TPR_MLP1_2 PF07926.7 EXF74926.1 - 0.00076 19.2 17.2 0.00076 19.2 11.9 13.4 5 2 7 13 13 13 5 TPR/MLP1/MLP2-like protein HALZ PF02183.13 EXF74926.1 - 0.0011 18.6 2.1 0.0011 18.6 1.5 14.5 16 1 2 18 18 18 1 Homeobox associated leucine zipper Spc7 PF08317.6 EXF74926.1 - 0.0025 16.5 22.6 0.0025 16.5 15.7 10.4 1 1 14 15 15 15 8 Spc7 kinetochore protein DUF1664 PF07889.7 EXF74926.1 - 0.0045 16.7 6.1 0.0045 16.7 4.2 12.9 4 3 8 15 15 15 1 Protein of unknown function (DUF1664) ADIP PF11559.3 EXF74926.1 - 0.0072 16.2 13.3 0.0072 16.2 9.2 13.7 2 2 9 13 13 13 4 Afadin- and alpha -actinin-Binding Myosin_tail_1 PF01576.14 EXF74926.1 - 0.39 8.3 249.5 0.31 8.6 26.1 6.7 1 1 6 7 7 7 0 Myosin tail Reo_sigmaC PF04582.7 EXF74926.1 - 2.3 7.3 72.8 0.31 10.1 3.4 9.1 1 1 5 10 10 10 0 Reovirus sigma C capsid protein Peptidase_C14 PF00656.17 EXF74927.1 - 1.7e-73 247.3 0.0 2.2e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 EXF74927.1 - 0.16 11.8 0.2 1 9.2 0.0 2.3 3 0 0 3 3 3 0 Raptor N-terminal CASPase like domain PAT1 PF09770.4 EXF74927.1 - 7.1 4.7 15.3 10 4.1 10.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 HD PF01966.17 EXF74929.1 - 5.3e-05 23.2 0.8 0.00046 20.1 0.2 2.3 2 1 0 2 2 2 1 HD domain Sec3_C PF09763.4 EXF74930.1 - 0.3 9.1 4.2 0.3 9.1 2.9 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Arf PF00025.16 EXF74931.1 - 2.3e-69 232.1 1.5 6.6e-36 123.1 0.3 2.0 2 0 0 2 2 2 2 ADP-ribosylation factor family G-alpha PF00503.15 EXF74931.1 - 9.6e-10 37.6 0.0 5.9e-06 25.2 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EXF74931.1 - 2.2e-09 36.7 0.1 0.00057 19.1 0.0 2.1 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EXF74931.1 - 5.7e-08 32.1 0.2 2.9e-07 29.8 0.1 1.8 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EXF74931.1 - 1.2e-07 31.3 0.0 1.4e-05 24.5 0.0 2.0 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EXF74931.1 - 2.2e-05 24.9 0.0 0.12 12.8 0.0 2.2 2 0 0 2 2 2 2 Miro-like protein 6PF2K PF01591.13 EXF74931.1 - 0.06 12.4 0.1 0.09 11.8 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase DUF1325 PF07039.6 EXF74932.1 - 1.6e-27 95.6 0.0 2.2e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 SGF29 tudor-like domain PMI_typeI PF01238.16 EXF74933.1 - 5.6e-138 459.9 0.0 6.5e-138 459.7 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I P2 PF07194.6 EXF74933.1 - 0.36 10.6 1.8 11 5.9 0.0 2.7 2 1 1 3 3 3 0 P2 response regulator binding domain Zn_clus PF00172.13 EXF74934.1 - 2.1e-08 33.9 5.5 3.2e-08 33.3 3.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF74935.1 - 0.00012 21.0 0.6 0.00025 20.0 0.4 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF74935.1 - 0.0026 17.6 12.4 0.012 15.5 8.6 2.0 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BLOC1_2 PF10046.4 EXF74935.1 - 0.11 12.6 0.5 0.31 11.2 0.3 1.7 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4629 PF15442.1 EXF74935.1 - 0.84 9.7 2.5 1.4 9.0 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) MFS_1 PF07690.11 EXF74936.1 - 3.8e-23 81.7 33.9 5.1e-22 78.0 21.2 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily HupE_UreJ PF04955.7 EXF74936.1 - 0.65 9.2 4.9 3.8 6.7 0.4 2.4 1 1 1 2 2 2 0 HupE / UreJ protein DUF1129 PF06570.6 EXF74936.1 - 0.85 8.8 0.0 0.85 8.8 0.0 2.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1129) DHDPS PF00701.17 EXF74937.1 - 5.2e-24 84.3 0.0 8.6e-24 83.6 0.0 1.3 1 1 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF3830 PF12903.2 EXF74938.1 - 3.5e-27 94.6 0.0 4.3e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3830) TauD PF02668.11 EXF74939.1 - 1.2e-33 116.8 0.2 1.6e-33 116.5 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EXF74939.1 - 0.058 13.9 0.1 8.1 7.0 0.0 2.4 2 0 0 2 2 2 0 2OG-Fe(II) oxygenase superfamily Colipase PF01114.13 EXF74940.1 - 0.0045 16.4 0.4 0.0045 16.4 0.3 2.1 2 0 0 2 2 2 1 Colipase, N-terminal domain Cupin_1 PF00190.17 EXF74942.1 - 1.6e-06 27.5 0.3 5.5e-06 25.8 0.2 1.7 1 1 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EXF74942.1 - 1.8e-05 24.1 2.6 2.5e-05 23.6 0.5 2.1 2 1 0 2 2 2 1 Cupin domain Auxin_BP PF02041.11 EXF74942.1 - 0.024 14.0 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 Auxin binding protein GPI PF06560.6 EXF74942.1 - 0.065 12.2 0.1 0.087 11.8 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) AA_permease PF00324.16 EXF74943.1 - 3.7e-59 200.3 29.0 5.3e-40 137.1 9.8 2.0 1 1 1 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EXF74943.1 - 2.1e-15 56.1 29.7 2.7e-11 42.6 10.3 2.1 1 1 1 2 2 2 2 Amino acid permease DUF4381 PF14316.1 EXF74943.1 - 1.5 8.9 4.8 5.7 7.0 3.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) Pyr_redox_3 PF13738.1 EXF74944.1 - 6.2e-20 72.1 0.0 1.3e-19 71.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EXF74944.1 - 1.8e-10 39.6 0.0 3.6e-10 38.6 0.0 1.5 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EXF74944.1 - 5.7e-10 39.0 0.3 2.7e-09 36.9 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF74944.1 - 2.1e-07 31.0 0.0 0.00048 20.0 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF74944.1 - 6.4e-06 25.3 0.0 0.00042 19.3 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase K_oxygenase PF13434.1 EXF74944.1 - 1.5e-05 24.0 0.0 0.00045 19.2 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.12 EXF74944.1 - 2e-05 23.8 0.3 4.5e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_9 PF13454.1 EXF74944.1 - 0.00015 21.5 2.0 0.002 17.8 0.0 3.1 3 1 0 3 3 3 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EXF74944.1 - 0.00049 19.1 0.0 0.023 13.6 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 EXF74944.1 - 0.0019 18.5 0.7 0.18 12.2 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EXF74944.1 - 0.0029 16.7 0.0 0.0083 15.2 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EXF74944.1 - 0.0039 17.0 0.0 2.1 8.1 0.0 2.2 2 0 0 2 2 2 2 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_2 PF00890.19 EXF74944.1 - 0.0068 15.2 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.15 EXF74944.1 - 0.01 15.9 0.0 5.1 7.1 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EXF74944.1 - 0.013 14.4 0.0 0.51 9.1 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 EXF74944.1 - 0.02 13.3 0.1 0.041 12.3 0.1 1.5 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.14 EXF74944.1 - 0.067 12.2 1.2 0.069 12.1 0.0 1.6 2 0 0 2 2 2 0 FAD binding domain NAD_binding_7 PF13241.1 EXF74944.1 - 0.084 13.1 0.0 19 5.5 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding F420_oxidored PF03807.12 EXF74944.1 - 0.18 12.2 0.1 21 5.6 0.0 2.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EXF74944.1 - 0.3 11.0 0.9 5.1 7.1 0.2 2.5 2 0 0 2 2 2 0 TrkA-N domain ThiF PF00899.16 EXF74944.1 - 0.3 10.8 2.5 0.88 9.3 0.0 2.2 2 0 0 2 2 2 0 ThiF family Usg PF06233.7 EXF74944.1 - 0.55 10.1 3.1 5.3 6.9 0.1 2.7 2 1 0 2 2 2 0 Usg-like family CoA_transf_3 PF02515.12 EXF74945.1 - 1.1e-26 93.2 0.3 1.3e-25 89.7 0.0 2.1 2 0 0 2 2 2 1 CoA-transferase family III 3HCDH_N PF02737.13 EXF74946.1 - 3.2e-45 153.9 0.0 4.5e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EXF74946.1 - 1.3e-14 54.3 0.0 2.7e-14 53.3 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain UDPG_MGDP_dh_N PF03721.9 EXF74946.1 - 8e-05 22.0 0.0 0.00014 21.3 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 EXF74946.1 - 0.0016 17.5 0.0 0.008 15.3 0.0 2.0 1 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EXF74946.1 - 0.0017 18.0 0.1 0.0051 16.5 0.0 1.8 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EXF74946.1 - 0.014 14.8 0.1 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 EXF74946.1 - 0.045 13.6 1.6 0.045 13.5 0.0 2.0 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase FAD_binding_3 PF01494.14 EXF74946.1 - 0.047 12.7 0.0 0.068 12.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain IlvN PF07991.7 EXF74946.1 - 0.067 12.5 0.1 0.81 9.0 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EXF74946.1 - 0.14 12.6 0.9 0.44 11.0 0.2 2.2 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Ldl_recept_b PF00058.12 EXF74947.1 - 5.5e-12 45.8 5.3 0.0011 19.2 0.1 5.3 5 1 0 5 5 5 3 Low-density lipoprotein receptor repeat class B SGL PF08450.7 EXF74947.1 - 0.00055 19.3 0.3 0.74 9.1 0.1 2.6 1 1 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EXF74947.1 - 0.035 14.1 0.3 7.2 6.7 0.0 3.2 2 1 0 3 3 3 0 Strictosidine synthase He_PIG PF05345.7 EXF74947.1 - 0.038 14.0 0.0 8.8 6.4 0.0 3.3 3 0 0 3 3 3 0 Putative Ig domain EHN PF06441.7 EXF74948.1 - 2.8e-30 104.4 0.0 5.4e-30 103.6 0.0 1.5 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EXF74948.1 - 3.9e-07 30.1 0.1 5.4e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF74948.1 - 0.00011 21.9 0.0 0.00016 21.2 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Methyltransf_7 PF03492.10 EXF74948.1 - 0.096 11.4 0.0 0.43 9.2 0.0 1.9 2 0 0 2 2 2 0 SAM dependent carboxyl methyltransferase NAD_binding_10 PF13460.1 EXF74949.1 - 4.3e-11 43.1 0.0 6.7e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EXF74949.1 - 8.4e-11 41.5 0.0 1.3e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EXF74949.1 - 3.7e-08 33.0 0.5 0.00023 20.6 0.1 2.4 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EXF74949.1 - 0.0012 17.8 0.2 0.4 9.5 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain KR PF08659.5 EXF74949.1 - 0.076 12.6 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 KR domain Alpha-L-AF_C PF06964.7 EXF74950.1 - 5.2e-35 120.8 0.0 8.5e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus Aldo_ket_red PF00248.16 EXF74951.1 - 1.5e-55 188.0 0.0 1.7e-55 187.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Cu_amine_oxid PF01179.15 EXF74953.1 - 6.3e-153 509.3 0.0 7.5e-153 509.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EXF74953.1 - 1.3e-08 34.7 0.1 2.4e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EXF74953.1 - 1.1e-05 25.4 0.0 2.5e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain adh_short PF00106.20 EXF74954.1 - 1.3e-35 122.7 5.0 1.8e-35 122.3 3.5 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF74954.1 - 1.6e-35 123.0 0.1 2e-35 122.7 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF74954.1 - 8.4e-20 71.1 1.8 1.1e-19 70.8 1.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF74954.1 - 6.5e-08 32.2 0.6 1.4e-07 31.1 0.4 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF74954.1 - 0.0007 19.6 4.3 0.011 15.8 3.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding HAD PF12710.2 EXF74954.1 - 0.0095 16.1 0.2 0.08 13.1 0.1 2.1 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase THF_DHG_CYH_C PF02882.14 EXF74954.1 - 0.012 14.7 0.0 0.022 13.8 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EXF74954.1 - 0.019 14.7 0.4 0.048 13.4 0.3 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KdpD PF02702.12 EXF74954.1 - 0.072 12.2 0.1 0.11 11.5 0.1 1.3 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain Cas_Cas02710 PF09670.5 EXF74954.1 - 0.12 10.9 0.0 0.17 10.4 0.0 1.2 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas02710) Fungal_trans_2 PF11951.3 EXF74955.1 - 0.00013 20.7 1.6 0.00018 20.2 1.1 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain PhyH PF05721.8 EXF74956.1 - 1.4e-22 80.7 0.2 1.9e-22 80.3 0.2 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Brix PF04427.13 EXF74957.1 - 1.8e-53 181.0 0.0 2.3e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 Brix domain DEAD PF00270.24 EXF74958.1 - 3e-45 153.7 0.0 5.1e-45 152.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF74958.1 - 2.4e-26 91.4 0.3 8.5e-26 89.6 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EXF74958.1 - 0.0024 17.7 0.0 0.014 15.2 0.0 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3827 PF12877.2 EXF74958.1 - 1.2 7.1 8.7 2 6.3 6.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Kinesin PF00225.18 EXF74959.1 - 3.3e-55 187.1 0.0 5.2e-55 186.4 0.0 1.4 1 1 0 1 1 1 1 Kinesin motor domain HALZ PF02183.13 EXF74959.1 - 0.1 12.3 1.0 0.29 10.8 0.7 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper HsbA PF12296.3 EXF74961.1 - 5.7e-25 87.5 4.4 5.7e-25 87.5 3.0 1.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A TFIIB PF00382.14 EXF74962.1 - 2.8e-34 116.7 9.9 8.1e-20 70.4 0.1 2.9 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EXF74962.1 - 3.1e-22 78.6 0.6 3.1e-22 78.6 0.4 3.3 4 0 0 4 4 4 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 EXF74962.1 - 1.2e-08 34.6 0.3 0.0055 16.2 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Rtf2 PF04641.7 EXF74962.1 - 0.02 14.1 0.4 0.02 14.1 0.3 2.7 2 1 1 3 3 3 0 Rtf2 RING-finger Rab5-bind PF09311.6 EXF74962.1 - 1 9.2 9.4 0.062 13.1 2.4 2.0 2 0 0 2 2 2 0 Rabaptin-like protein DUF1349 PF07081.6 EXF74963.1 - 9.8e-22 77.1 0.8 1.2e-21 76.9 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Peptidase_S24 PF00717.18 EXF74965.1 - 5e-08 32.4 0.0 7.8e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like BTB PF00651.26 EXF74968.1 - 9.8e-08 31.9 0.0 2.6e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain Rubella_E2 PF05749.6 EXF74968.1 - 0.078 12.2 0.2 0.078 12.2 0.1 2.0 2 0 0 2 2 2 0 Rubella membrane glycoprotein E2 Abhydrolase_6 PF12697.2 EXF74969.1 - 1.2e-19 71.0 0.4 1.2e-19 71.0 0.2 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF74969.1 - 1.9e-09 37.4 0.1 0.0015 18.2 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF74969.1 - 6.5e-07 29.1 0.0 1.7e-06 27.7 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold ATP-synt_E PF05680.7 EXF74969.1 - 0.054 13.4 0.0 0.41 10.6 0.0 2.4 2 0 0 2 2 2 0 ATP synthase E chain DLH PF01738.13 EXF74969.1 - 0.092 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family FA_hydroxylase PF04116.8 EXF74970.1 - 6.8e-05 23.2 5.1 6.8e-05 23.2 3.6 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3808 PF10300.4 EXF74971.1 - 1.1e-126 423.2 0.7 1.3e-126 422.8 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_19 PF14559.1 EXF74971.1 - 0.057 13.7 12.9 1.1 9.6 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 EXF74971.1 - 0.057 13.6 0.5 25 5.3 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EXF74971.1 - 0.12 12.2 2.2 0.72 9.8 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.1 EXF74971.1 - 0.39 10.4 10.4 0.24 11.0 1.1 4.1 5 0 0 5 5 5 0 TPR repeat TPR_4 PF07721.9 EXF74971.1 - 1.2 9.7 0.0 1.2 9.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EXF74971.1 - 2.4 8.9 9.8 7.8 7.3 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EXF74971.1 - 2.5 8.1 8.0 1.3 9.0 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EXF74971.1 - 5.7 6.9 7.4 3.8 7.5 0.0 4.0 3 1 2 5 5 5 0 Tetratricopeptide repeat UQ_con PF00179.21 EXF74972.1 - 7.9e-43 145.2 0.0 1e-42 144.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EXF74972.1 - 7.9e-05 22.4 0.0 0.00014 21.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EXF74972.1 - 0.0042 16.9 0.0 0.0063 16.4 0.0 1.4 1 0 0 1 1 1 1 RWD domain DUF4597 PF15366.1 EXF74972.1 - 0.021 14.3 0.2 0.021 14.3 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4597) UEV PF05743.8 EXF74972.1 - 0.031 13.9 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 UEV domain RabGAP-TBC PF00566.13 EXF74973.1 - 1e-38 133.0 1.0 1.6e-34 119.2 0.0 3.6 2 1 1 3 3 3 2 Rab-GTPase-TBC domain YfbU PF03887.9 EXF74973.1 - 0.17 11.4 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 YfbU domain ABC_tran PF00005.22 EXF74974.1 - 8.9e-49 165.3 0.7 8.3e-23 81.2 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 EXF74974.1 - 2.7e-20 71.9 8.0 2.7e-20 71.9 5.5 3.6 5 0 0 5 5 3 1 ABC transporter AAA_21 PF13304.1 EXF74974.1 - 7.3e-18 65.5 0.1 0.0002 21.4 0.0 4.5 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 EXF74974.1 - 3e-11 42.9 1.5 0.0039 16.4 0.0 4.5 4 0 0 4 4 4 4 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EXF74974.1 - 2.4e-09 38.0 0.3 0.0044 17.8 0.0 3.2 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 EXF74974.1 - 7.6e-07 28.5 0.2 0.016 14.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EXF74974.1 - 1.9e-06 27.8 0.0 0.021 14.7 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EXF74974.1 - 2.2e-06 26.9 0.0 0.033 13.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 EXF74974.1 - 4.8e-06 25.8 3.4 0.29 10.1 0.1 3.9 4 2 0 4 4 4 2 AAA ATPase domain Miro PF08477.8 EXF74974.1 - 1e-05 25.9 0.1 0.094 13.2 0.0 3.1 2 0 0 2 2 2 2 Miro-like protein AAA_33 PF13671.1 EXF74974.1 - 2.1e-05 24.4 0.0 0.11 12.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EXF74974.1 - 2.8e-05 24.1 0.6 0.02 14.8 0.1 2.8 2 0 0 2 2 2 1 AAA ATPase domain MobB PF03205.9 EXF74974.1 - 3.6e-05 23.4 0.4 0.2 11.3 0.2 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_23 PF13476.1 EXF74974.1 - 6e-05 23.4 17.3 0.0061 16.8 0.1 4.6 5 0 0 5 5 5 2 AAA domain AAA_22 PF13401.1 EXF74974.1 - 8.4e-05 22.7 0.1 1.1 9.3 0.1 3.4 3 1 0 3 3 2 2 AAA domain AAA_18 PF13238.1 EXF74974.1 - 9.6e-05 22.6 5.9 0.098 12.9 0.0 3.4 5 0 0 5 5 2 2 AAA domain AAA PF00004.24 EXF74974.1 - 0.00015 21.9 0.0 0.13 12.4 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EXF74974.1 - 0.00021 21.1 0.1 0.9 9.4 0.0 3.1 3 0 0 3 3 2 2 AAA domain SbcCD_C PF13558.1 EXF74974.1 - 0.00023 20.9 0.3 3.1 7.7 0.2 4.1 3 2 0 3 3 3 1 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 EXF74974.1 - 0.00034 19.4 0.7 0.76 8.5 0.1 3.1 3 0 0 3 3 3 2 ArgK protein AAA_28 PF13521.1 EXF74974.1 - 0.00039 20.4 2.4 0.14 12.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EXF74974.1 - 0.0012 18.5 0.1 1.7 8.2 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_10 PF12846.2 EXF74974.1 - 0.0016 17.9 0.0 1.2 8.4 0.1 3.3 3 0 0 3 3 3 1 AAA-like domain NTPase_1 PF03266.10 EXF74974.1 - 0.0023 17.6 0.1 0.41 10.3 0.1 2.7 2 0 0 2 2 2 1 NTPase RNA_helicase PF00910.17 EXF74974.1 - 0.0025 17.9 0.0 1.5 9.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase Dynamin_N PF00350.18 EXF74974.1 - 0.0027 17.5 7.2 0.27 11.0 0.0 4.1 4 1 0 4 4 4 1 Dynamin family Zeta_toxin PF06414.7 EXF74974.1 - 0.007 15.4 0.3 0.14 11.2 0.0 2.7 3 0 0 3 3 3 1 Zeta toxin cobW PF02492.14 EXF74974.1 - 0.0081 15.6 1.0 1.6 8.1 0.5 2.6 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 EXF74974.1 - 0.0088 15.4 0.0 3.9 6.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.20 EXF74974.1 - 0.0099 15.3 0.1 4 6.8 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 EXF74974.1 - 0.017 14.8 0.3 5.5 6.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) GTP_EFTU PF00009.22 EXF74974.1 - 0.02 14.3 1.6 4.4 6.7 0.0 3.1 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain NB-ARC PF00931.17 EXF74974.1 - 0.027 13.3 0.0 5.3 5.8 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain PduV-EutP PF10662.4 EXF74974.1 - 0.064 12.7 0.1 13 5.2 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF87 PF01935.12 EXF74974.1 - 0.23 11.2 7.2 0.58 9.9 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function DUF87 SRP54 PF00448.17 EXF74974.1 - 0.28 10.5 4.4 3.2 7.1 0.0 3.5 4 0 0 4 4 3 0 SRP54-type protein, GTPase domain Tubulin PF00091.20 EXF74975.1 - 1.7e-70 237.2 0.0 2.9e-70 236.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EXF74975.1 - 8.7e-49 164.7 0.1 1.5e-48 164.0 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EXF74975.1 - 5.3e-06 26.4 0.0 1.8e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EXF74975.1 - 0.0052 16.2 0.0 0.0092 15.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Ribosomal_L6 PF00347.18 EXF74976.1 - 1.8e-22 79.5 0.0 7e-11 42.4 0.0 3.5 3 1 0 3 3 3 2 Ribosomal protein L6 Inositol_P PF00459.20 EXF74977.1 - 1.1e-50 172.5 3.3 1.9e-50 171.6 2.3 1.4 1 1 0 1 1 1 1 Inositol monophosphatase family DUF2630 PF10944.3 EXF74977.1 - 0.087 12.9 0.3 0.17 12.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2630) Complex1_LYR_2 PF13233.1 EXF74978.1 - 1.6e-20 73.5 0.2 1.9e-20 73.2 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EXF74978.1 - 0.0095 15.7 2.4 0.017 14.8 1.0 1.8 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Aha1_N PF09229.6 EXF74980.1 - 1.4e-38 131.8 0.3 2.4e-38 131.0 0.2 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EXF74980.1 - 2.2e-16 60.0 1.2 4e-16 59.2 0.2 1.9 2 0 0 2 2 2 1 Activator of Hsp90 ATPase homolog 1-like protein zf-DHHC PF01529.15 EXF74981.1 - 2.6e-33 114.8 2.8 2.6e-33 114.8 1.9 1.9 2 1 0 2 2 2 1 DHHC palmitoyltransferase DUF2456 PF10445.4 EXF74981.1 - 0.017 15.0 0.4 0.057 13.3 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2456) Rap1_C PF11626.3 EXF74982.1 - 3.2e-24 84.6 0.9 6.3e-23 80.4 0.0 2.9 3 1 0 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 EXF74982.1 - 7.3e-13 48.1 7.0 1.5e-11 43.9 0.1 3.3 3 0 0 3 3 3 2 Rap1 Myb domain Rap1-DNA-bind PF09197.5 EXF74982.1 - 2.5e-09 37.6 1.4 0.0005 20.5 0.0 3.0 2 0 0 2 2 2 2 Rap1, DNA-binding ARID PF01388.16 EXF74982.1 - 2.3e-05 24.1 0.0 6.4e-05 22.7 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain BRCT PF00533.21 EXF74982.1 - 0.01 15.9 0.0 0.021 14.9 0.0 1.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain CN_hydrolase PF00795.17 EXF74983.1 - 5.6e-29 100.8 0.0 7.7e-29 100.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase LysM PF01476.15 EXF74984.1 - 0.0089 15.9 0.1 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 LysM domain HLH PF00010.21 EXF74985.1 - 3.1e-17 62.0 0.0 6.3e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Peptidase_M24 PF00557.19 EXF74986.1 - 2.8e-48 164.2 0.0 4.1e-48 163.7 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EXF74986.1 - 2.7e-36 123.9 0.0 5.7e-36 122.8 0.0 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Dfp1_Him1_M PF08630.5 EXF74987.1 - 3.6e-35 120.4 0.0 8.9e-35 119.1 0.0 1.7 1 0 0 1 1 1 1 Dfp1/Him1, central region zf-DBF PF07535.7 EXF74987.1 - 2.1e-24 84.9 0.6 3.7e-24 84.1 0.4 1.4 1 0 0 1 1 1 1 DBF zinc finger Tropomyosin_1 PF12718.2 EXF74987.1 - 0.0017 18.2 0.4 0.0062 16.3 0.3 2.0 1 0 0 1 1 1 1 Tropomyosin like BRCT PF00533.21 EXF74987.1 - 0.03 14.4 0.0 0.075 13.1 0.0 1.6 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EXF74987.1 - 0.051 13.4 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain Lyase_aromatic PF00221.14 EXF74988.1 - 6.5e-157 522.7 1.3 8.7e-157 522.3 0.9 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase APG12 PF04110.8 EXF74989.1 - 4.2e-28 97.3 0.0 5.3e-28 97.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EXF74989.1 - 5.7e-07 29.4 0.0 7e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pantoate_transf PF02548.10 EXF74990.1 - 6.2e-103 343.4 0.1 7.2e-103 343.2 0.1 1.0 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.1 EXF74990.1 - 4.1e-10 39.2 1.5 1.2e-09 37.7 1.0 1.7 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase UQ_con PF00179.21 EXF74991.1 - 2.9e-33 114.2 0.1 3.7e-33 113.9 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF572 PF04502.8 EXF74992.1 - 8.2e-61 206.0 0.0 1e-60 205.6 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Fungal_trans PF04082.13 EXF74993.1 - 2.2e-24 85.7 0.0 3.3e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF74993.1 - 0.0072 16.2 7.3 0.013 15.3 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ZZ PF00569.12 EXF74993.1 - 1.5 8.4 4.7 2.9 7.5 3.3 1.3 1 0 0 1 1 1 0 Zinc finger, ZZ type SIR2 PF02146.12 EXF74994.1 - 6.2e-39 133.5 0.0 1e-38 132.8 0.0 1.3 1 1 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.17 EXF74994.1 - 0.073 12.8 0.0 2.5 7.8 0.0 2.3 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain ADH_zinc_N PF00107.21 EXF74995.1 - 4.4e-21 74.8 0.0 7.4e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF74995.1 - 1.9e-20 72.6 6.2 3e-20 71.9 4.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EXF74995.1 - 1e-07 32.9 0.0 2e-07 31.9 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EXF74995.1 - 0.0044 16.1 0.2 0.0069 15.5 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EXF74995.1 - 0.015 15.4 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_16 PF00722.16 EXF74996.1 - 1.8e-44 151.2 1.4 1.8e-44 151.2 1.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Abhydrolase_2 PF02230.11 EXF74997.1 - 4.7e-27 94.8 0.0 5.7e-10 38.9 0.0 3.1 3 0 0 3 3 3 3 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EXF74997.1 - 6.8e-08 32.6 0.4 1.9e-07 31.2 0.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF74997.1 - 4.9e-06 26.3 0.0 1.2e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF74997.1 - 0.00015 21.0 0.0 0.0005 19.3 0.0 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family LIP PF03583.9 EXF74997.1 - 0.074 12.2 0.0 0.38 9.9 0.0 1.9 2 0 0 2 2 2 0 Secretory lipase FSH1 PF03959.8 EXF74997.1 - 0.12 11.7 0.1 1.3 8.4 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EXF74997.1 - 0.16 11.4 0.1 1.7 8.1 0.0 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold DHDPS PF00701.17 EXF74998.1 - 2.3e-38 131.4 0.0 3.1e-38 131.0 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family HTH_29 PF13551.1 EXF74998.1 - 0.024 14.7 0.1 0.24 11.5 0.0 2.4 2 1 1 3 3 3 0 Winged helix-turn helix Tyrosinase PF00264.15 EXF74999.1 - 2.9e-44 151.8 0.0 4.1e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF791 PF05631.9 EXF75000.1 - 1.3e-68 231.3 5.7 1.8e-68 230.8 3.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 EXF75000.1 - 3.1e-23 82.0 28.0 3.1e-23 82.0 19.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF75000.1 - 4.4e-07 28.8 2.5 4.4e-07 28.8 1.7 3.1 1 1 1 2 2 2 2 Sugar (and other) transporter Reticulon PF02453.12 EXF75000.1 - 1.5 8.3 8.8 5.3 6.6 1.7 3.0 3 0 0 3 3 3 0 Reticulon DUF2678 PF10856.3 EXF75000.1 - 5.8 6.6 6.5 2 8.1 0.1 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2678) Glyco_hydro_92 PF07971.7 EXF75001.1 - 6.2e-25 87.7 0.0 8.6e-25 87.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Glyco_hydro_92 PF07971.7 EXF75002.1 - 3e-120 402.2 0.1 3.7e-120 401.9 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 zf-primase PF09329.6 EXF75003.1 - 5.1e-17 61.1 1.5 9.7e-17 60.2 1.1 1.5 1 0 0 1 1 1 1 Primase zinc finger tRNA_anti-codon PF01336.20 EXF75003.1 - 0.14 12.0 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain RNase_H2-Ydr279 PF09468.5 EXF75004.1 - 1.9e-81 273.5 5.3 3.2e-81 272.8 3.7 1.3 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) DASH_Duo1 PF08651.5 EXF75005.1 - 1e-29 101.8 1.4 1.5e-29 101.3 0.9 1.2 1 0 0 1 1 1 1 DASH complex subunit Duo1 DUF3367 PF11847.3 EXF75005.1 - 0.033 12.1 1.3 0.035 12.0 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) DUF1035 PF06281.7 EXF75005.1 - 0.17 11.6 0.1 0.3 10.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1035) DUF1682 PF07946.9 EXF75005.1 - 0.24 10.2 3.6 0.32 9.7 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) CAF-1_p150 PF11600.3 EXF75005.1 - 4.2 6.7 18.7 4.8 6.4 9.4 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TTL PF03133.10 EXF75007.1 - 5.7e-55 186.3 0.0 8.7e-55 185.7 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SurE PF01975.12 EXF75007.1 - 5.3e-45 153.1 0.0 7.8e-45 152.5 0.0 1.2 1 0 0 1 1 1 1 Survival protein SurE ATPgrasp_YheCD PF14398.1 EXF75007.1 - 0.00063 18.6 0.0 0.0017 17.1 0.0 1.7 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 EXF75007.1 - 0.027 14.2 0.0 0.52 10.0 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain RNase_P_p30 PF01876.11 EXF75007.1 - 0.28 10.4 0.0 0.51 9.5 0.0 1.3 1 0 0 1 1 1 0 RNase P subunit p30 E1-E2_ATPase PF00122.15 EXF75009.1 - 1.9e-54 184.1 1.3 1.9e-54 184.1 0.9 2.2 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EXF75009.1 - 1.7e-41 141.7 8.0 1.7e-41 141.7 5.6 2.5 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EXF75009.1 - 5.3e-29 102.1 0.0 2.3e-28 100.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EXF75009.1 - 2e-19 69.3 0.0 4.3e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EXF75009.1 - 1.4e-17 64.4 0.0 2.9e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EXF75009.1 - 1.2e-06 28.3 0.4 7.9e-06 25.6 0.3 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EXF75009.1 - 0.00017 21.0 0.0 0.0014 18.0 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus DUF1510 PF07423.6 EXF75009.1 - 3.6 6.9 8.2 1.4 8.2 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) SIR2 PF02146.12 EXF75010.1 - 1.1e-61 207.7 0.0 1.8e-61 206.9 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF592 PF04574.8 EXF75010.1 - 8.4e-06 25.4 0.0 2.1e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF592) TPP_enzyme_M PF00205.17 EXF75010.1 - 0.00097 18.9 0.1 1.6 8.4 0.1 2.4 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain Pkinase PF00069.20 EXF75011.1 - 2e-16 59.9 0.0 5.4e-16 58.5 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF75011.1 - 6.4e-10 38.5 0.0 5.5e-09 35.4 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Aminotran_4 PF01063.14 EXF75012.1 - 1e-30 106.9 0.0 1.4e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV ESSS PF10183.4 EXF75013.1 - 1.6e-24 86.2 0.2 2e-24 86.0 0.1 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Dna2 PF08696.6 EXF75014.1 - 3.7e-72 242.0 0.4 3.7e-72 242.0 0.3 2.1 2 0 0 2 2 2 1 DNA replication factor Dna2 AAA_12 PF13087.1 EXF75014.1 - 2.1e-51 174.1 0.0 4.8e-51 172.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EXF75014.1 - 1e-40 139.8 0.2 1.4e-20 73.8 0.0 2.8 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.1 EXF75014.1 - 1.6e-12 47.4 0.0 4.7e-12 45.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain Cas_Cas4 PF01930.12 EXF75014.1 - 2.2e-12 47.1 0.9 1.3e-08 34.8 0.1 2.4 2 0 0 2 2 2 2 Domain of unknown function DUF83 AAA_19 PF13245.1 EXF75014.1 - 2.5e-11 43.1 0.2 6.4e-11 41.8 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain PDDEXK_1 PF12705.2 EXF75014.1 - 2.8e-07 30.1 0.0 6.2e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 PD-(D/E)XK nuclease superfamily Viral_helicase1 PF01443.13 EXF75014.1 - 5.6e-07 29.3 0.2 0.26 10.7 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Helicase_RecD PF05127.9 EXF75014.1 - 7.7e-05 22.3 0.0 0.00032 20.3 0.0 2.1 2 0 0 2 2 2 1 Helicase SRP54 PF00448.17 EXF75014.1 - 0.00089 18.7 0.1 0.0018 17.7 0.1 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain UvrD-helicase PF00580.16 EXF75014.1 - 0.0012 18.2 0.0 0.0012 18.2 0.0 2.2 3 0 0 3 3 2 1 UvrD/REP helicase N-terminal domain MobB PF03205.9 EXF75014.1 - 0.0012 18.5 0.2 0.0047 16.6 0.1 2.0 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EXF75014.1 - 0.0014 18.0 0.0 0.0043 16.4 0.0 1.8 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain PIF1 PF05970.9 EXF75014.1 - 0.0016 17.4 0.1 0.012 14.6 0.0 2.1 1 1 0 1 1 1 1 PIF1-like helicase AAA_16 PF13191.1 EXF75014.1 - 0.0027 17.7 0.0 0.011 15.7 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.1 EXF75014.1 - 0.013 14.9 0.0 0.08 12.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EXF75014.1 - 0.024 13.6 0.0 0.049 12.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.12 EXF75014.1 - 0.07 12.9 2.5 0.11 12.3 0.2 2.4 3 0 0 3 3 3 0 Domain of unknown function DUF87 ArgK PF03308.11 EXF75014.1 - 0.076 11.7 0.0 0.18 10.5 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA_22 PF13401.1 EXF75014.1 - 0.087 12.9 0.1 0.33 11.0 0.0 2.0 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EXF75014.1 - 0.11 12.2 0.2 0.28 10.8 0.1 1.6 1 0 0 1 1 1 0 NTPase McrBC PF10117.4 EXF75015.1 - 0.017 14.0 0.1 0.029 13.3 0.1 1.2 1 0 0 1 1 1 0 McrBC 5-methylcytosine restriction system component LTXXQ PF07813.7 EXF75015.1 - 8.2 6.9 14.9 4.9 7.6 1.7 2.5 2 0 0 2 2 2 0 LTXXQ motif family protein F-box-like PF12937.2 EXF75016.1 - 2.6e-07 30.2 0.1 8e-07 28.6 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EXF75016.1 - 4.3e-05 23.0 0.1 8.7e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 F-box domain p450 PF00067.17 EXF75017.1 - 4.8e-37 127.5 0.0 2.1e-36 125.4 0.0 2.0 3 0 0 3 3 3 1 Cytochrome P450 DUF3210 PF11489.3 EXF75018.1 - 6e-191 636.7 84.2 6e-191 636.7 58.4 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3210) Cg6151-P PF10233.4 EXF75019.1 - 9.6e-37 125.4 15.6 1.1e-36 125.1 10.8 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein CG6151-P YIF1 PF03878.10 EXF75019.1 - 0.21 10.7 6.6 0.29 10.2 4.6 1.1 1 0 0 1 1 1 0 YIF1 OCD_Mu_crystall PF02423.10 EXF75021.1 - 3.8e-16 58.7 0.1 1e-09 37.6 0.0 2.8 3 0 0 3 3 3 2 Ornithine cyclodeaminase/mu-crystallin family UPF0370 PF13980.1 EXF75021.1 - 0.11 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) Ribosomal_S16 PF00886.14 EXF75021.1 - 0.13 11.9 0.0 0.54 10.0 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S16 PepSY_TM_3 PF13706.1 EXF75022.1 - 0.093 12.1 0.1 0.21 10.9 0.1 1.7 1 0 0 1 1 1 0 PepSY-associated TM helix Usp PF00582.21 EXF75023.1 - 3.2e-23 82.4 0.9 2.3e-14 53.8 0.3 2.7 2 0 0 2 2 2 2 Universal stress protein family Ribosomal_S7 PF00177.16 EXF75024.1 - 1.8e-23 82.7 0.0 3.5e-23 81.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e dsrm PF00035.20 EXF75025.1 - 0.00032 21.2 0.0 0.00047 20.6 0.0 1.2 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 EXF75025.1 - 0.0023 18.1 0.0 0.0062 16.8 0.0 1.7 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 PhyH PF05721.8 EXF75026.1 - 0.13 12.2 0.0 0.18 11.8 0.0 1.2 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) tRNA_int_end_N2 PF12928.2 EXF75029.1 - 2.8e-14 52.3 0.1 5.1e-14 51.4 0.1 1.4 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.9 EXF75029.1 - 0.056 13.0 0.2 0.13 11.7 0.1 1.6 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain G6PD_bact PF10786.4 EXF75029.1 - 0.092 12.1 0.7 1.3 8.3 0.1 2.1 2 0 0 2 2 2 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) GSDH PF07995.6 EXF75032.1 - 0.0002 20.5 0.4 0.00094 18.3 0.2 2.2 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase NHL PF01436.16 EXF75032.1 - 0.09 12.7 0.0 27 4.9 0.0 3.6 2 1 1 3 3 3 0 NHL repeat WD40 PF00400.27 EXF75033.1 - 1.2e-47 158.1 20.5 1.5e-11 43.6 0.0 6.4 6 1 0 6 6 6 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EXF75033.1 - 1.5e-08 34.5 11.6 0.0076 15.9 1.4 4.2 2 2 1 3 3 3 2 Transcription factor IIIC subunit delta N-term IKI3 PF04762.7 EXF75033.1 - 0.068 10.9 3.5 0.93 7.2 0.0 2.1 2 0 0 2 2 2 0 IKI3 family bZIP_1 PF00170.16 EXF75035.1 - 3.3e-11 42.9 3.9 6.4e-11 42.0 2.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EXF75035.1 - 7.6e-06 25.6 7.9 1.8e-05 24.4 5.5 1.6 1 0 0 1 1 1 1 Basic region leucine zipper TTKRSYEDQ PF10212.4 EXF75035.1 - 0.069 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein DUF1680 PF07944.7 EXF75036.1 - 4.6e-135 450.8 0.3 5.2e-135 450.6 0.2 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Lactamase_B PF00753.22 EXF75037.1 - 8.9e-16 58.1 0.2 1.6e-15 57.2 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EXF75037.1 - 5.4e-05 22.8 0.2 0.0031 17.1 0.1 2.0 1 1 1 2 2 2 2 Beta-lactamase superfamily domain PH_6 PF15406.1 EXF75037.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain Oxidored_FMN PF00724.15 EXF75038.1 - 2.1e-50 171.6 0.0 2.9e-50 171.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EXF75038.1 - 4.7e-06 25.6 0.0 1.2e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) AP_endonuc_2 PF01261.19 EXF75038.1 - 0.0022 17.3 0.0 0.94 8.7 0.0 2.4 1 1 0 2 2 2 2 Xylose isomerase-like TIM barrel MTHFR PF02219.12 EXF75038.1 - 0.097 11.7 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Methylenetetrahydrofolate reductase Glyco_hydro_16 PF00722.16 EXF75039.1 - 2.7e-13 49.6 0.0 3.7e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 EXF75039.1 - 3.5e-06 25.4 2.1 0.0061 14.7 1.8 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Acetyltransf_2 PF00797.12 EXF75040.1 - 2.3e-38 132.1 0.2 1.9e-37 129.1 0.1 2.1 1 1 0 1 1 1 1 N-acetyltransferase Transglut_core PF01841.14 EXF75040.1 - 0.0045 17.1 0.1 0.13 12.4 0.0 2.6 3 0 0 3 3 3 1 Transglutaminase-like superfamily Shisa PF13908.1 EXF75041.1 - 5.8e-05 23.3 0.0 7.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 EXF75041.1 - 0.0001 22.6 0.1 0.00023 21.4 0.1 1.6 1 1 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.6 EXF75041.1 - 0.0014 18.2 0.3 0.0019 17.9 0.2 1.2 1 0 0 1 1 1 1 Protocadherin Herpes_gE PF02480.11 EXF75041.1 - 0.014 13.7 0.0 0.014 13.6 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E IncA PF04156.9 EXF75041.1 - 0.019 14.5 0.5 0.032 13.8 0.3 1.5 1 1 0 1 1 1 0 IncA protein SIT PF15330.1 EXF75041.1 - 0.02 15.0 0.0 0.043 13.9 0.0 1.5 2 0 0 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT TMEM154 PF15102.1 EXF75041.1 - 0.023 14.4 0.0 0.048 13.3 0.0 1.5 1 1 1 2 2 2 0 TMEM154 protein family DUF4446 PF14584.1 EXF75041.1 - 0.039 13.7 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) VirionAssem_T7 PF11653.3 EXF75041.1 - 0.044 14.5 2.2 0.044 14.5 1.5 1.6 2 0 0 2 2 1 0 Bacteriophage T7 virion assembly protein WBP-1 PF11669.3 EXF75041.1 - 0.047 13.7 1.1 0.092 12.8 0.6 1.4 1 1 0 1 1 1 0 WW domain-binding protein 1 RCR PF12273.3 EXF75041.1 - 0.089 13.3 0.9 0.089 13.3 0.7 2.1 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red Tetraspannin PF00335.15 EXF75041.1 - 0.1 11.8 3.8 0.16 11.1 2.6 1.2 1 0 0 1 1 1 0 Tetraspanin family Imm36 PF15597.1 EXF75041.1 - 0.13 12.4 0.1 0.2 11.8 0.1 1.3 1 0 0 1 1 1 0 Immunity protein 36 DUF4448 PF14610.1 EXF75041.1 - 0.13 11.6 0.4 0.22 10.9 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DAG1 PF05454.6 EXF75041.1 - 0.63 9.1 3.0 0.78 8.8 1.8 1.3 1 1 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) Peptidase_S8 PF00082.17 EXF75042.1 - 7.7e-33 113.8 1.8 7.7e-33 113.8 1.3 1.8 2 0 0 2 2 2 1 Subtilase family SIP1 PF04938.7 EXF75042.1 - 0.022 14.1 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Lactamase_B_2 PF12706.2 EXF75043.1 - 0.037 13.5 0.1 3.4 7.1 0.0 2.2 2 0 0 2 2 2 0 Beta-lactamase superfamily domain Tetradecapep PF08187.6 EXF75043.1 - 0.078 12.8 0.1 0.28 11.0 0.1 2.0 1 0 0 1 1 1 0 Myoactive tetradecapeptides family Amino_oxidase PF01593.19 EXF75045.1 - 1.3e-60 205.8 0.1 4.7e-60 203.9 0.1 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Clr5 PF14420.1 EXF75045.1 - 1.2e-14 53.8 3.8 1.2e-14 53.8 2.6 2.3 2 0 0 2 2 2 1 Clr5 domain NAD_binding_8 PF13450.1 EXF75045.1 - 3.9e-09 36.4 0.0 1.2e-08 34.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EXF75045.1 - 2.1e-05 24.6 0.2 0.00015 21.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF75045.1 - 0.00087 19.6 0.3 0.089 13.2 0.1 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF75045.1 - 0.0022 16.9 0.1 0.0041 16.0 0.1 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.19 EXF75045.1 - 0.03 13.2 0.1 0.6 8.9 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EXF75045.1 - 0.043 12.8 0.1 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 EXF75045.1 - 0.045 13.6 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF75045.1 - 0.05 12.4 0.6 0.079 11.7 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EXF75045.1 - 0.055 12.5 0.1 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.15 EXF75045.1 - 0.14 12.2 0.7 0.3 11.1 0.1 1.8 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_9 PF13454.1 EXF75045.1 - 0.18 11.5 1.4 1.2 8.9 0.1 2.6 2 1 0 2 2 2 0 FAD-NAD(P)-binding DUF2781 PF10914.3 EXF75047.1 - 9.8e-29 100.0 10.2 1.2e-28 99.7 7.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) EBP PF05241.7 EXF75047.1 - 0.031 13.2 5.6 0.02 13.9 2.3 1.7 2 0 0 2 2 2 0 Emopamil binding protein p450 PF00067.17 EXF75048.1 - 1.2e-70 238.3 0.0 1.6e-70 237.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EXF75049.1 - 1.1e-45 155.9 25.3 1.1e-45 155.9 17.6 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF75049.1 - 4.6e-12 45.2 5.4 8.3e-12 44.4 3.7 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 EXF75049.1 - 3.3e-05 22.2 1.9 4.4e-05 21.7 1.3 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector CDC50 PF03381.10 EXF75050.1 - 9.9e-75 251.2 0.0 1.4e-74 250.7 0.0 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family E1-E2_ATPase PF00122.15 EXF75051.1 - 7e-17 61.2 0.0 1.3e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EXF75051.1 - 3e-13 50.7 0.0 2.3e-09 38.0 0.0 2.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EXF75051.1 - 6.6e-13 49.2 0.0 6.5e-12 46.0 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EXF75051.1 - 4e-09 36.2 0.0 1.6e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EXF75051.1 - 0.0048 16.5 0.2 0.014 15.0 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HCV_NS5a_1b PF08301.8 EXF75051.1 - 0.058 13.7 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 Hepatitis C virus non-structural 5a domain 1b DUF3278 PF11683.3 EXF75051.1 - 0.13 12.2 0.3 4.9 7.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) PBP PF01161.15 EXF75052.1 - 5.5e-16 58.7 0.0 1.7e-15 57.1 0.0 1.7 2 0 0 2 2 2 1 Phosphatidylethanolamine-binding protein NAD_binding_10 PF13460.1 EXF75053.1 - 1.1e-05 25.5 0.0 1.1e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding Fungal_trans_2 PF11951.3 EXF75054.1 - 4.2e-42 144.1 0.5 6.1e-42 143.5 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF75054.1 - 9.1e-07 28.6 4.1 2e-06 27.5 2.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4281 PF14108.1 EXF75054.1 - 0.086 12.9 0.5 0.29 11.2 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4281) Peptidase_S8 PF00082.17 EXF75055.1 - 7.6e-46 156.5 0.0 2.4e-45 154.8 0.0 1.9 1 1 0 1 1 1 1 Subtilase family ADH_N PF08240.7 EXF75055.1 - 1.1e-20 73.4 4.1 1.3e-20 73.1 2.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF75055.1 - 1.2e-20 73.4 0.1 3e-20 72.0 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF1034 PF06280.7 EXF75055.1 - 3.3e-16 59.6 0.1 7e-16 58.6 0.1 1.6 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) ADH_zinc_N_2 PF13602.1 EXF75055.1 - 2.8e-06 28.2 0.1 8.2e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EXF75055.1 - 0.00076 18.6 0.1 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EXF75055.1 - 0.037 14.1 0.0 0.099 12.7 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AlaDh_PNT_C PF01262.16 EXF75055.1 - 0.72 9.4 3.3 0.35 10.4 0.1 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Asn_synthase PF00733.16 EXF75056.1 - 8.3e-53 179.4 0.0 1.1e-52 179.0 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EXF75056.1 - 5.6e-37 126.2 0.0 9e-37 125.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EXF75056.1 - 8.4e-35 119.6 0.0 1.5e-34 118.7 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EXF75056.1 - 3.2e-06 26.5 0.0 5.7e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EXF75056.1 - 0.00047 18.9 0.1 0.98 8.0 0.0 3.5 2 1 2 4 4 4 2 Glutamine amidotransferases class-II NAD_synthase PF02540.12 EXF75056.1 - 0.0026 16.7 0.0 0.0042 16.0 0.0 1.2 1 0 0 1 1 1 1 NAD synthase tRNA_Me_trans PF03054.11 EXF75056.1 - 0.26 9.7 0.0 0.42 9.1 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase GFA PF04828.9 EXF75057.1 - 3.8e-22 78.0 0.1 4.9e-22 77.6 0.1 1.1 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EXF75057.1 - 0.035 13.3 0.2 0.035 13.3 0.1 1.8 2 0 0 2 2 2 0 zinc-ribbon domain Auto_anti-p27 PF06677.7 EXF75057.1 - 0.036 13.8 0.6 0.17 11.6 0.0 2.1 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Med4 PF10018.4 EXF75058.1 - 0.0056 16.0 4.2 0.0096 15.3 2.9 1.3 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 CTP_transf_2 PF01467.21 EXF75058.1 - 0.014 15.4 0.0 0.18 11.8 0.0 2.5 3 0 0 3 3 3 0 Cytidylyltransferase Ribosomal_60s PF00428.14 EXF75058.1 - 0.23 11.8 6.0 0.54 10.6 4.2 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein Myc_N PF01056.13 EXF75058.1 - 0.24 10.5 2.0 0.43 9.6 1.4 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Daxx PF03344.10 EXF75058.1 - 0.28 9.6 4.9 0.41 9.0 3.4 1.2 1 0 0 1 1 1 0 Daxx Family Glycos_transf_1 PF00534.15 EXF75059.1 - 4.8e-32 110.7 0.0 1.6e-31 109.0 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EXF75059.1 - 6.4e-09 36.1 0.1 1.5e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 EXF75059.1 - 1.4e-07 31.7 0.1 3.6e-06 27.1 0.0 2.8 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EXF75059.1 - 1.9e-07 31.0 0.0 2.6e-06 27.2 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_2 PF13524.1 EXF75059.1 - 0.0015 18.7 0.0 0.0031 17.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF3951 PF13131.1 EXF75059.1 - 0.16 11.7 0.2 0.38 10.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) ECH PF00378.15 EXF75060.1 - 5.7e-19 68.2 0.0 7.2e-19 67.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EXF75060.1 - 0.00061 19.5 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 2 Peptidase family S49 RabGAP-TBC PF00566.13 EXF75061.1 - 4.6e-49 166.7 0.1 7.9e-49 166.0 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain U79_P34 PF03064.11 EXF75061.1 - 0.037 13.5 2.8 0.078 12.4 0.8 2.2 3 0 0 3 3 3 0 HSV U79 / HCMV P34 Pox_H7 PF04787.7 EXF75061.1 - 0.34 10.7 1.3 0.73 9.6 0.3 1.9 2 0 0 2 2 2 0 Late protein H7 LRR_4 PF12799.2 EXF75062.1 - 2.7e-30 103.4 32.4 4.5e-07 29.3 3.9 7.8 4 2 2 8 8 8 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EXF75062.1 - 1.5e-22 79.1 33.4 2e-09 37.0 1.3 6.4 4 1 3 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 EXF75062.1 - 6.3e-10 37.6 30.8 0.49 10.6 0.5 11.8 10 3 1 11 11 11 4 Leucine Rich Repeat LRR_6 PF13516.1 EXF75062.1 - 8.5e-07 28.4 26.5 6.6 7.1 0.0 9.8 9 1 1 10 10 10 3 Leucine Rich repeat LRR_7 PF13504.1 EXF75062.1 - 3e-06 26.5 30.6 4.3 7.9 0.0 11.6 11 0 0 11 11 11 1 Leucine rich repeat LRR_9 PF14580.1 EXF75062.1 - 2.1e-05 24.1 13.7 0.15 11.5 0.7 4.4 2 1 2 4 4 4 3 Leucine-rich repeat DUF433 PF04255.9 EXF75062.1 - 0.28 10.6 0.0 0.67 9.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF433) IPK PF03770.11 EXF75066.1 - 5.4e-57 192.6 0.0 2.3e-56 190.5 0.0 1.9 2 0 0 2 2 2 1 Inositol polyphosphate kinase DAO PF01266.19 EXF75067.1 - 4.6e-39 134.3 13.4 2e-38 132.2 9.3 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF75067.1 - 0.0084 16.1 0.4 0.03 14.3 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF1625 PF07787.7 EXF75068.1 - 0.011 15.0 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) DUF3784 PF12650.2 EXF75068.1 - 0.039 13.9 1.2 0.069 13.0 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3784) BPL_N PF09825.4 EXF75068.1 - 0.076 11.7 0.3 0.1 11.3 0.2 1.3 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF2207 PF09972.4 EXF75068.1 - 0.42 9.1 4.0 0.64 8.5 2.8 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) SdpI PF13630.1 EXF75068.1 - 1.9 8.2 9.6 0.14 11.8 2.7 1.8 2 0 0 2 2 2 0 SdpI/YhfL protein family CN_hydrolase PF00795.17 EXF75071.1 - 1.8e-19 69.8 0.0 2.5e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase HATPase_c_3 PF13589.1 EXF75073.1 - 1.1e-14 54.2 0.0 2.2e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MutL_C PF08676.6 EXF75073.1 - 3.2e-11 43.0 0.1 9e-10 38.3 0.0 2.4 2 0 0 2 2 2 1 MutL C terminal dimerisation domain HATPase_c PF02518.21 EXF75073.1 - 0.0032 17.1 0.0 0.0071 16.0 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase His_Phos_1 PF00300.17 EXF75074.1 - 5.9e-14 52.4 0.0 7.7e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) UPF0239 PF06783.6 EXF75075.1 - 0.064 13.1 0.0 0.099 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) PUCC PF03209.10 EXF75075.1 - 0.067 11.8 0.1 0.072 11.7 0.1 1.2 1 0 0 1 1 1 0 PUCC protein T2SM PF04612.7 EXF75075.1 - 0.33 10.7 4.1 6.5 6.5 2.0 2.0 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M Pec_lyase_C PF00544.14 EXF75076.1 - 2.5e-22 79.3 6.0 3.9e-22 78.7 4.1 1.3 1 0 0 1 1 1 1 Pectate lyase MFS_1 PF07690.11 EXF75077.1 - 6.9e-40 136.8 20.1 6.9e-40 136.8 14.0 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1616 PF07760.6 EXF75077.1 - 0.004 16.3 4.1 0.36 9.9 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1616) ATG22 PF11700.3 EXF75077.1 - 0.28 9.5 15.6 0.016 13.6 4.6 2.8 2 1 1 3 3 3 0 Vacuole effluxer Atg22 like Aldedh PF00171.17 EXF75080.1 - 1.4e-161 537.9 0.1 1.5e-161 537.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EXF75080.1 - 0.017 14.3 0.0 0.11 11.6 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) DUF126 PF01989.11 EXF75080.1 - 1.2 8.8 3.8 15 5.3 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function DUF126 Aminotran_3 PF00202.16 EXF75081.1 - 1.7e-98 329.6 0.0 2e-98 329.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III HAD_2 PF13419.1 EXF75082.1 - 4.5e-24 85.6 0.1 5.8e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EXF75082.1 - 0.0034 17.8 0.0 0.0073 16.7 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Tachystatin_B PF11478.3 EXF75082.1 - 0.11 12.2 1.0 0.18 11.5 0.1 1.8 2 0 0 2 2 2 0 Antimicrobial chitin binding protein tachystatin B DUF730 PF05325.6 EXF75082.1 - 0.13 12.0 0.1 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF730) DAO PF01266.19 EXF75083.1 - 1.9e-52 178.3 0.1 2.3e-52 178.1 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EXF75083.1 - 9e-10 38.9 0.0 0.0004 20.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF75083.1 - 3.1e-05 23.0 0.5 0.00065 18.6 0.4 2.1 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EXF75083.1 - 0.00015 21.7 0.0 0.00047 20.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EXF75083.1 - 0.00016 21.4 0.1 0.008 15.9 0.1 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.12 EXF75083.1 - 0.00019 20.5 0.0 0.00046 19.3 0.0 1.6 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EXF75083.1 - 0.0023 16.4 0.0 0.22 9.9 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_2 PF07992.9 EXF75083.1 - 0.0042 16.9 0.1 0.12 12.1 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF75083.1 - 0.025 13.4 0.0 0.13 11.1 0.0 2.0 2 1 0 2 2 2 0 Lycopene cyclase protein Fungal_trans PF04082.13 EXF75084.1 - 2.8e-21 75.5 0.0 4.7e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Oxidored_molyb PF00174.14 EXF75085.1 - 3e-51 173.1 0.0 5e-51 172.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EXF75085.1 - 8.5e-23 80.4 1.8 1.4e-22 79.6 1.2 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain HTH_24 PF13412.1 EXF75085.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Na_Ca_ex PF01699.19 EXF75086.1 - 1e-31 109.4 23.9 5.3e-19 68.1 7.0 3.7 4 0 0 4 4 4 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EXF75086.1 - 4.6e-14 52.5 10.9 4.6e-14 52.5 7.5 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF307) AAA PF00004.24 EXF75087.1 - 5.2e-44 149.6 0.0 8.5e-44 148.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EXF75087.1 - 3.1e-08 33.4 0.0 7.5e-08 32.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EXF75087.1 - 1.2e-07 31.8 0.0 2.2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EXF75087.1 - 3.3e-06 27.1 0.0 9.5e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EXF75087.1 - 4.9e-06 26.7 0.1 0.00025 21.1 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EXF75087.1 - 6.2e-05 23.7 0.0 0.00015 22.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EXF75087.1 - 7.7e-05 21.8 0.0 0.00013 21.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EXF75087.1 - 0.00014 21.5 0.1 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EXF75087.1 - 0.00042 19.7 0.0 0.00076 18.9 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EXF75087.1 - 0.00089 18.0 0.0 0.0016 17.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EXF75087.1 - 0.0014 18.5 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EXF75087.1 - 0.0017 18.2 0.0 0.0029 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EXF75087.1 - 0.0023 17.5 0.0 0.0074 15.8 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EXF75087.1 - 0.0024 17.0 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EXF75087.1 - 0.0038 17.1 0.0 0.0067 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EXF75087.1 - 0.0051 15.9 0.1 0.017 14.2 0.0 1.8 2 0 0 2 2 2 1 KaiC AAA_18 PF13238.1 EXF75087.1 - 0.0063 16.8 0.1 0.028 14.7 0.0 2.2 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.16 EXF75087.1 - 0.0068 15.5 0.0 0.015 14.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EXF75087.1 - 0.017 14.4 0.1 0.081 12.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain PhoH PF02562.11 EXF75087.1 - 0.018 14.2 0.0 0.07 12.3 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein DUF815 PF05673.8 EXF75087.1 - 0.018 13.9 0.0 0.033 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 EXF75087.1 - 0.019 14.4 0.0 0.085 12.3 0.0 2.0 3 0 0 3 3 2 0 Sigma-54 interaction domain AAA_24 PF13479.1 EXF75087.1 - 0.021 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF2072 PF09845.4 EXF75087.1 - 0.027 14.3 0.1 0.059 13.2 0.1 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) RNA_helicase PF00910.17 EXF75087.1 - 0.028 14.5 0.0 0.053 13.6 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Histone PF00125.19 EXF75087.1 - 0.044 13.8 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Sigma54_activ_2 PF14532.1 EXF75087.1 - 0.046 13.7 0.0 0.12 12.4 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EXF75087.1 - 0.047 12.5 0.0 0.086 11.7 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NB-ARC PF00931.17 EXF75087.1 - 0.076 11.8 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain NACHT PF05729.7 EXF75087.1 - 0.099 12.3 0.0 0.53 9.9 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Y_phosphatase PF00102.22 EXF75088.1 - 5.1e-60 202.7 0.0 6.1e-33 114.1 0.0 3.2 3 0 0 3 3 3 3 Protein-tyrosine phosphatase Rhodanese PF00581.15 EXF75088.1 - 1.6e-12 47.7 0.0 3.8e-12 46.5 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Y_phosphatase3 PF13350.1 EXF75088.1 - 0.019 15.2 0.1 0.061 13.5 0.1 1.8 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.15 EXF75088.1 - 0.021 14.3 0.1 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain MFS_1 PF07690.11 EXF75089.1 - 5.1e-10 38.6 17.6 5.1e-10 38.6 12.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EXF75089.1 - 0.00011 21.7 1.4 0.00011 21.7 0.9 2.5 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 EXF75089.1 - 0.047 12.2 10.7 0.026 13.1 4.0 2.2 2 0 0 2 2 2 0 Sugar (and other) transporter PhyH PF05721.8 EXF75090.1 - 2.9e-09 37.2 0.1 7.4e-09 35.9 0.1 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EXF75090.1 - 8.3e-07 27.8 0.0 7e-05 21.4 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_3 PF13640.1 EXF75090.1 - 0.023 15.1 0.0 0.056 13.9 0.0 1.6 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2-Hacid_dh_C PF02826.14 EXF75091.1 - 3.7e-43 146.7 0.0 8.4e-29 99.9 0.0 2.1 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EXF75091.1 - 0.016 15.2 0.0 0.067 13.1 0.0 1.9 2 0 0 2 2 2 0 NADH(P)-binding SnoaL_2 PF12680.2 EXF75093.1 - 0.00049 20.4 0.1 0.00077 19.8 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain MFS_1 PF07690.11 EXF75094.1 - 4.6e-10 38.7 62.5 1.4e-07 30.5 22.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF75094.1 - 1.1e-05 23.8 19.3 1.8e-05 23.1 13.4 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Pox_A14 PF05767.7 EXF75094.1 - 0.78 9.7 7.8 0.18 11.7 1.6 2.8 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Phage_tail PF04630.7 EXF75095.1 - 0.0025 16.9 0.1 0.0029 16.7 0.1 1.3 1 0 0 1 1 1 1 Phage major tail protein p450 PF00067.17 EXF75097.1 - 3e-76 256.8 0.0 3.4e-76 256.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_76 PF03663.9 EXF75098.1 - 6.6e-145 483.1 19.7 9.8e-145 482.5 13.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Fungal_trans PF04082.13 EXF75098.1 - 1.4e-23 83.1 0.0 2.5e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF75098.1 - 1.7e-06 27.8 14.2 3.3e-06 26.9 9.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HalX PF08663.5 EXF75098.1 - 0.39 10.7 3.2 0.68 9.9 1.0 2.3 2 0 0 2 2 2 0 HalX domain Dickkopf_N PF04706.7 EXF75098.1 - 1.5 9.0 12.0 3.7 7.7 8.3 1.6 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region NUDIX PF00293.23 EXF75099.1 - 1.3e-12 47.4 0.2 1.7e-12 47.1 0.1 1.2 1 0 0 1 1 1 1 NUDIX domain PAN_4 PF14295.1 EXF75100.1 - 0.012 15.3 1.9 0.012 15.3 1.3 2.9 2 1 0 2 2 2 0 PAN domain Pectate_lyase PF03211.8 EXF75103.1 - 1.7e-50 171.4 5.2 1.7e-50 171.4 3.6 1.5 2 0 0 2 2 2 1 Pectate lyase DIM PF08194.7 EXF75103.1 - 0.15 12.0 4.3 8 6.5 0.3 2.9 2 0 0 2 2 2 0 DIM protein PAP2 PF01569.16 EXF75104.1 - 5e-22 77.9 2.9 5e-22 77.9 2.0 2.0 2 0 0 2 2 2 1 PAP2 superfamily PAP2_C PF14360.1 EXF75104.1 - 1.2 9.5 9.9 0.19 12.0 2.9 2.5 2 1 0 2 2 2 0 PAP2 superfamily C-terminal Glyoxalase PF00903.20 EXF75105.1 - 1.6e-09 37.7 0.0 2.2e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EXF75105.1 - 2.1e-07 31.5 0.0 3.2e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain ATP-synt_J PF04911.7 EXF75105.1 - 0.0031 16.9 0.0 0.0082 15.5 0.0 1.7 1 0 0 1 1 1 1 ATP synthase j chain GMC_oxred_N PF00732.14 EXF75109.1 - 1.9e-48 165.1 0.0 2.5e-48 164.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF75109.1 - 8.1e-39 133.1 0.0 2.1e-38 131.8 0.0 1.7 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EXF75109.1 - 0.00027 19.9 0.1 0.0043 16.0 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF75109.1 - 0.0009 18.2 0.3 0.0016 17.4 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EXF75109.1 - 0.0011 18.9 0.1 0.0031 17.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HHH_5 PF14520.1 EXF75109.1 - 0.038 14.1 1.5 3 8.0 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain Pyr_redox_2 PF07992.9 EXF75109.1 - 0.047 13.5 0.2 0.093 12.5 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF75109.1 - 0.051 12.4 1.4 0.083 11.7 1.0 1.3 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EXF75109.1 - 0.13 10.6 0.3 0.45 8.9 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 EXF75109.1 - 0.15 11.8 0.6 0.3 10.8 0.4 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Peptidase_S28 PF05577.7 EXF75110.1 - 1.2e-47 162.4 0.1 1.2e-38 132.9 0.0 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 EXF75110.1 - 0.00061 19.7 0.6 0.0011 18.8 0.1 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family PQ-loop PF04193.9 EXF75111.1 - 9.8e-23 79.4 3.2 4.2e-17 61.4 0.5 2.6 2 0 0 2 2 2 2 PQ loop repeat Sigma_reg_C PF13791.1 EXF75111.1 - 0.095 12.7 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Sigma factor regulator C-terminal Ada_Zn_binding PF02805.11 EXF75113.1 - 2.3e-26 91.1 1.8 3.6e-26 90.5 1.2 1.3 1 0 0 1 1 1 1 Metal binding domain of Ada HTH_AraC PF00165.18 EXF75113.1 - 5.9e-05 22.7 0.3 0.00019 21.1 0.0 1.9 2 0 0 2 2 2 1 Bacterial regulatory helix-turn-helix proteins, AraC family HTH_18 PF12833.2 EXF75113.1 - 0.00078 19.5 0.1 0.0019 18.2 0.0 1.7 2 0 0 2 2 2 1 Helix-turn-helix domain Sugar_tr PF00083.19 EXF75114.1 - 2.9e-81 273.3 16.5 3.3e-81 273.1 11.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF75114.1 - 4.1e-31 107.9 19.5 5.7e-31 107.5 13.5 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EXF75114.1 - 1.9e-05 23.0 6.0 4.8e-05 21.7 1.2 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Phage_holin_2 PF04550.7 EXF75114.1 - 0.086 12.9 0.6 0.22 11.6 0.4 1.6 1 0 0 1 1 1 0 Phage holin family 2 TypeIII_RM_meth PF12564.3 EXF75114.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.5 1 0 0 1 1 1 0 Type III restriction/modification enzyme methylation subunit MFS_1 PF07690.11 EXF75116.1 - 7e-28 97.3 57.2 4.4e-23 81.5 21.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily p450 PF00067.17 EXF75117.1 - 2.7e-45 154.7 0.0 2.6e-26 92.1 0.0 3.0 3 0 0 3 3 3 3 Cytochrome P450 GMC_oxred_N PF00732.14 EXF75118.1 - 1.1e-52 179.0 0.0 1.4e-52 178.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF75118.1 - 2.6e-37 128.2 0.0 4.5e-37 127.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EXF75118.1 - 0.00012 21.1 1.6 0.0065 15.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF75118.1 - 0.00062 18.7 0.5 0.0011 17.9 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EXF75118.1 - 0.012 15.5 0.2 0.038 14.0 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF75118.1 - 0.037 13.9 0.2 0.85 9.4 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Hist_deacetyl PF00850.14 EXF75120.1 - 3e-78 263.2 0.1 4.6e-78 262.6 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain JAB PF01398.16 EXF75122.1 - 1.8e-34 117.9 0.0 4e-34 116.7 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EXF75122.1 - 1.9e-26 92.4 1.0 4.2e-26 91.3 0.7 1.6 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EXF75122.1 - 2.3e-08 33.5 0.0 3.8e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain MauE PF07291.6 EXF75124.1 - 0.052 13.1 8.4 0.37 10.3 0.5 2.1 1 1 1 2 2 2 0 Methylamine utilisation protein MauE DUF202 PF02656.10 EXF75124.1 - 4.6 7.5 7.7 2e+02 2.2 5.4 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Protamine_3 PF08188.6 EXF75125.1 - 0.067 13.1 2.8 0.13 12.2 1.9 1.5 1 0 0 1 1 1 0 Spermatozal protamine family CHORD PF04968.7 EXF75127.1 - 0.003 17.7 0.1 0.003 17.7 0.1 2.6 2 1 0 2 2 2 1 CHORD BTK PF00779.14 EXF75127.1 - 0.82 9.3 4.3 1.1 8.8 0.9 2.4 2 0 0 2 2 2 0 BTK motif PAF-AH_p_II PF03403.8 EXF75130.1 - 6e-36 123.5 0.0 8.8e-36 122.9 0.0 1.1 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EXF75130.1 - 9.8e-11 41.5 0.1 2.9e-10 40.0 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF75130.1 - 0.0091 15.8 0.0 0.023 14.5 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EXF75130.1 - 0.07 12.0 0.0 0.49 9.2 0.0 2.0 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_3 PF07859.8 EXF75130.1 - 0.12 11.8 0.0 0.36 10.3 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Cutinase PF01083.17 EXF75131.1 - 2.6e-46 157.5 5.3 3.2e-46 157.3 3.7 1.0 1 0 0 1 1 1 1 Cutinase Abhydrolase_5 PF12695.2 EXF75131.1 - 0.0006 19.5 0.1 0.00071 19.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 EXF75131.1 - 0.00082 18.8 0.1 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 EXF75131.1 - 0.0014 18.4 0.0 0.0031 17.3 0.0 1.5 1 1 0 1 1 1 1 Bacterial virulence protein (VirJ) FSH1 PF03959.8 EXF75131.1 - 0.041 13.3 0.0 0.15 11.4 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EXF75131.1 - 0.061 12.8 0.0 0.076 12.5 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF4440 PF14534.1 EXF75134.1 - 7.3e-10 39.0 0.0 8.8e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) JCAD PF15351.1 EXF75135.1 - 0.27 8.7 9.0 0.43 8.1 6.3 1.2 1 0 0 1 1 1 0 Junctional protein associated with coronary artery disease CDC45 PF02724.9 EXF75135.1 - 0.55 8.2 7.3 0.67 7.9 5.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 EXF75135.1 - 6.4 6.0 15.2 11 5.3 10.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DIOX_N PF14226.1 EXF75136.1 - 3.1e-19 69.5 0.0 7.1e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EXF75136.1 - 9.7e-17 61.0 0.0 3.8e-16 59.2 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 EXF75137.1 - 5.7e-21 74.8 0.0 1e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HET PF06985.6 EXF75137.1 - 3e-18 66.3 0.0 8.1e-18 64.9 0.0 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase_Tyr PF07714.12 EXF75137.1 - 4.2e-10 39.1 0.0 7.3e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EXF75138.1 - 1.6e-23 83.1 0.0 2.2e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF75138.1 - 6e-13 48.4 0.0 8.7e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Fungal_trans_2 PF11951.3 EXF75139.1 - 5.1e-56 189.9 0.9 5.1e-56 189.9 0.6 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF75139.1 - 1.1e-07 31.6 6.4 2.4e-07 30.5 4.4 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KNOX2 PF03791.8 EXF75139.1 - 0.022 14.0 0.0 0.048 12.9 0.0 1.6 1 0 0 1 1 1 0 KNOX2 domain DUF605 PF04652.11 EXF75139.1 - 1.6 8.0 16.6 0.19 11.0 8.0 1.8 2 0 0 2 2 2 0 Vta1 like BAF1_ABF1 PF04684.8 EXF75139.1 - 9.2 4.9 10.8 14 4.3 7.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Fmp27 PF10344.4 EXF75140.1 - 1.1e-234 781.1 0.0 1.7e-234 780.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial protein from FMP27 Apt1 PF10351.4 EXF75140.1 - 4.6e-167 556.5 0.4 4.6e-167 556.5 0.3 2.3 2 0 0 2 2 2 1 Golgi-body localisation protein domain Fmp27_WPPW PF10359.4 EXF75140.1 - 2.1e-148 494.7 0.1 4.4e-148 493.6 0.0 1.6 2 0 0 2 2 2 1 RNA pol II promoter Fmp27 protein domain DUF2405 PF10293.4 EXF75140.1 - 4.9e-54 182.3 0.1 1.3e-53 180.9 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2405) Fmp27_GFWDK PF10347.4 EXF75140.1 - 6.1e-53 178.9 0.0 1.3e-52 177.9 0.0 1.6 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Fmp27_SW PF10305.4 EXF75140.1 - 1.3e-31 109.0 0.0 4.9e-31 107.2 0.0 2.1 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain JAB PF01398.16 EXF75142.1 - 6.1e-30 103.3 0.0 9.7e-30 102.6 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EXF75142.1 - 2.7e-07 30.1 0.0 5.1e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Polysacc_deac_1 PF01522.16 EXF75145.1 - 1.4e-14 53.7 0.0 2.8e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase 2_5_RNA_ligase2 PF13563.1 EXF75149.1 - 8.4e-29 100.2 0.1 2e-28 99.0 0.0 1.7 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily PAP_central PF04928.12 EXF75149.1 - 2e-24 85.8 0.0 3.6e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase central domain Exo_endo_phos PF03372.18 EXF75149.1 - 7.7e-16 58.7 0.1 1.8e-15 57.5 0.1 1.7 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF504 PF04457.7 EXF75149.1 - 9.1e-09 35.3 0.2 2.1e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF504) NTP_transf_2 PF01909.18 EXF75149.1 - 0.00048 20.4 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_RNA-bind PF04926.10 EXF75149.1 - 0.00064 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain Exo70 PF03081.10 EXF75150.1 - 6.6e-73 245.6 0.0 1.9e-72 244.1 0.0 1.7 2 0 0 2 2 2 1 Exo70 exocyst complex subunit RHD3 PF05879.7 EXF75150.1 - 0.039 11.8 0.3 0.073 10.9 0.2 1.3 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) Retro_M PF02813.9 EXF75150.1 - 0.096 12.8 0.3 2.5 8.3 0.0 3.0 3 0 0 3 3 3 0 Retroviral M domain Baculo_PEP_C PF04513.7 EXF75150.1 - 0.23 11.2 7.3 18 5.1 0.7 4.1 4 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus GAS PF13851.1 EXF75150.1 - 0.24 10.5 8.4 7 5.7 0.1 3.5 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding CENP-Q PF13094.1 EXF75150.1 - 5.2 7.0 8.1 2.9 7.8 2.9 2.5 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Aminotran_3 PF00202.16 EXF75151.1 - 3.6e-81 272.6 0.0 4.2e-81 272.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III MCM PF00493.18 EXF75152.1 - 2e-128 427.8 0.3 2.8e-128 427.3 0.2 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EXF75152.1 - 2.1e-15 57.2 0.0 1.1e-14 54.9 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EXF75152.1 - 2.1e-07 30.3 0.0 2.7e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EXF75152.1 - 0.0047 16.5 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EXF75152.1 - 0.014 14.8 0.0 0.037 13.5 0.0 1.6 2 0 0 2 2 2 0 Sigma-54 interaction domain FAM176 PF14851.1 EXF75152.1 - 1.5 8.4 5.2 1.4 8.6 2.1 2.0 1 1 0 1 1 1 0 FAM176 family PfkB PF00294.19 EXF75153.1 - 4.1e-17 62.2 0.1 2e-09 37.0 0.3 2.1 2 0 0 2 2 2 2 pfkB family carbohydrate kinase Rho_Binding PF08912.6 EXF75155.1 - 0.94 9.8 4.2 0.32 11.3 1.0 1.6 2 0 0 2 2 2 0 Rho Binding adh_short_C2 PF13561.1 EXF75156.1 - 3.9e-29 102.0 0.7 4.8e-29 101.8 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EXF75156.1 - 1.2e-27 96.9 0.3 1.5e-27 96.5 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF75156.1 - 9.3e-15 54.7 0.2 1.3e-14 54.2 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF75156.1 - 0.002 17.5 0.6 0.0035 16.7 0.4 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Ras_bdg_2 PF14847.1 EXF75156.1 - 0.0065 16.3 0.1 0.011 15.6 0.1 1.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 DAO PF01266.19 EXF75157.1 - 1e-12 47.6 0.5 4.9e-06 25.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 EXF75157.1 - 5.3e-10 38.7 2.1 4.6e-08 32.4 0.1 2.3 2 0 0 2 2 2 2 Thi4 family NAD_binding_8 PF13450.1 EXF75157.1 - 1.7e-09 37.5 0.3 4.4e-09 36.2 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EXF75157.1 - 7.3e-08 31.6 1.9 5.7e-06 25.4 1.0 2.2 2 0 0 2 2 2 1 FAD binding domain Amino_oxidase PF01593.19 EXF75157.1 - 1.2e-07 31.1 0.1 3.7e-06 26.2 0.0 2.6 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase GDI PF00996.13 EXF75157.1 - 3.5e-06 25.6 0.0 2.1e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 GDP dissociation inhibitor Pyr_redox_2 PF07992.9 EXF75157.1 - 8.4e-05 22.5 0.0 0.00018 21.4 0.0 1.5 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EXF75157.1 - 0.00039 19.6 0.8 0.001 18.2 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EXF75157.1 - 0.00072 18.7 0.1 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EXF75157.1 - 0.0011 17.5 0.9 0.0023 16.4 0.3 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EXF75157.1 - 0.0019 18.5 1.0 0.042 14.2 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF75157.1 - 0.0032 17.5 0.0 0.0075 16.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF75157.1 - 0.0083 15.0 1.1 0.016 14.1 0.7 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A Strep_67kDa_ant PF06100.6 EXF75157.1 - 0.016 13.6 0.1 0.024 13.0 0.1 1.1 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family Trp_halogenase PF04820.9 EXF75157.1 - 0.1 11.2 0.6 0.14 10.7 0.4 1.1 1 0 0 1 1 1 0 Tryptophan halogenase UDPG_MGDP_dh_N PF03721.9 EXF75157.1 - 0.17 11.2 0.1 0.3 10.4 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Fungal_trans PF04082.13 EXF75158.1 - 2.3e-14 52.9 3.4 4.5e-14 51.9 2.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EXF75158.1 - 0.00024 21.2 2.1 0.00033 20.7 0.2 2.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EXF75158.1 - 0.00057 20.0 8.1 0.0016 18.6 1.0 3.8 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF75158.1 - 0.0049 17.1 9.8 0.013 15.7 1.0 3.9 3 0 0 3 3 3 1 Zinc finger, C2H2 type Peptidase_S15 PF02129.13 EXF75159.1 - 1.1e-36 126.6 1.1 4e-33 114.9 0.8 2.4 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EXF75159.1 - 1.6e-29 103.4 0.0 2.5e-29 102.7 0.0 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 EXF75159.1 - 5.3e-10 39.5 0.1 2e-09 37.6 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase family EthD PF07110.6 EXF75159.1 - 1.8e-08 35.2 0.4 7.7e-07 29.9 0.0 2.7 3 0 0 3 3 3 1 EthD domain Abhydrolase_5 PF12695.2 EXF75159.1 - 0.00046 19.9 0.0 0.00099 18.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF75159.1 - 0.0016 17.7 0.2 0.014 14.5 0.1 2.3 1 1 0 1 1 1 1 Prolyl oligopeptidase family LRR_4 PF12799.2 EXF75160.1 - 1.8e-14 52.9 16.9 0.00044 19.8 0.1 5.8 5 1 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EXF75160.1 - 3.2e-12 44.6 22.1 0.33 11.1 0.0 9.6 10 0 0 10 10 10 5 Leucine Rich Repeat LRR_8 PF13855.1 EXF75160.1 - 4e-08 32.8 13.7 0.013 15.1 1.3 5.0 2 1 2 4 4 4 3 Leucine rich repeat LRR_6 PF13516.1 EXF75160.1 - 0.00013 21.7 15.9 5.2 7.4 0.0 7.7 5 2 3 8 8 8 3 Leucine Rich repeat LRRNT_2 PF08263.7 EXF75160.1 - 0.00044 20.1 0.3 0.0009 19.1 0.2 1.6 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_7 PF13504.1 EXF75160.1 - 0.029 14.4 15.0 18 6.1 0.0 8.1 10 0 0 10 10 10 0 Leucine rich repeat Glyco_hydro_2_N PF02837.13 EXF75161.1 - 2e-28 99.0 0.0 3.8e-28 98.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EXF75161.1 - 1.7e-11 43.5 0.1 3.5e-11 42.5 0.0 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EXF75161.1 - 4.2e-09 36.8 0.0 9.3e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Aa_trans PF01490.13 EXF75162.1 - 9.9e-45 152.7 27.1 1.1e-44 152.5 18.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EXF75162.1 - 7.4e-06 25.0 10.9 7.4e-06 25.0 7.6 2.1 1 1 1 2 2 2 1 Tryptophan/tyrosine permease family Spore_permease PF03845.8 EXF75162.1 - 0.0042 15.7 9.1 0.0072 15.0 0.7 2.5 2 0 0 2 2 2 2 Spore germination protein DUF433 PF04255.9 EXF75162.1 - 0.11 11.9 0.5 0.26 10.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF433) FA_hydroxylase PF04116.8 EXF75162.1 - 1.4 9.3 23.5 0.07 13.5 5.6 3.8 3 2 0 3 3 3 0 Fatty acid hydroxylase superfamily Kelch_5 PF13854.1 EXF75163.1 - 4e-15 55.3 7.5 3.2e-07 30.1 0.1 4.8 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.1 EXF75163.1 - 2e-09 37.3 21.9 3.5e-05 23.8 0.0 6.6 7 1 0 7 7 7 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EXF75163.1 - 3.8e-09 36.3 12.1 0.022 14.9 0.1 5.7 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.1 EXF75163.1 - 3.4e-08 33.1 11.7 0.036 13.8 0.4 6.2 4 2 1 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.10 EXF75163.1 - 0.00014 21.4 2.3 0.056 13.2 0.0 4.2 4 0 0 4 4 4 1 Kelch motif Kelch_1 PF01344.20 EXF75163.1 - 0.00037 19.9 6.6 0.067 12.7 0.0 4.8 5 0 0 5 5 5 1 Kelch motif Nop14 PF04147.7 EXF75163.1 - 0.11 10.4 4.8 0.15 9.9 3.4 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EXF75163.1 - 4.6 5.1 8.1 6.6 4.6 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Pyr_redox_2 PF07992.9 EXF75164.1 - 1.1e-14 54.7 0.0 1.6e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF75164.1 - 2.1e-05 24.6 0.2 0.15 12.1 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF75164.1 - 0.00011 21.1 0.6 0.08 11.7 0.0 2.3 1 1 1 2 2 2 2 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EXF75164.1 - 0.00012 21.9 0.7 0.48 10.1 0.0 2.6 3 0 0 3 3 3 2 FAD-NAD(P)-binding HI0933_like PF03486.9 EXF75164.1 - 0.00022 19.8 0.1 0.0016 16.9 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EXF75164.1 - 0.00046 19.3 0.1 0.008 15.2 0.0 2.1 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 EXF75164.1 - 0.00057 18.9 0.0 0.24 10.2 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EXF75164.1 - 0.00067 19.6 0.0 0.0018 18.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EXF75164.1 - 0.00068 18.5 2.4 0.0038 16.1 0.1 2.5 2 1 0 3 3 3 1 FAD binding domain DAO PF01266.19 EXF75164.1 - 0.0015 17.5 1.9 0.022 13.6 0.1 2.2 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EXF75164.1 - 0.011 14.8 0.0 0.022 13.7 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EXF75164.1 - 0.029 13.2 0.1 0.14 11.0 0.0 1.9 1 1 0 2 2 2 0 Lycopene cyclase protein DIOX_N PF14226.1 EXF75165.1 - 3.8e-14 53.2 0.1 9.3e-14 51.9 0.1 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EXF75165.1 - 1e-11 45.0 0.0 2.5e-11 43.7 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily OxoDH_E1alpha_N PF12573.3 EXF75165.1 - 0.48 10.0 3.8 1.6 8.2 0.0 2.8 3 0 0 3 3 3 0 2-oxoisovalerate dehydrogenase E1 alpha subunit N terminal MFS_1 PF07690.11 EXF75166.1 - 2.5e-26 92.2 35.9 2.5e-26 92.2 24.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TrkH PF02386.11 EXF75167.1 - 2.6e-97 325.5 5.5 4.1e-94 315.0 0.4 2.2 2 0 0 2 2 2 2 Cation transport protein CUE PF02845.11 EXF75168.1 - 1.2e-07 31.1 0.0 2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 CUE domain LAP2alpha PF11560.3 EXF75169.1 - 0.14 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 2 alpha ADH_zinc_N_2 PF13602.1 EXF75170.1 - 3e-23 83.1 0.2 6.6e-23 81.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EXF75170.1 - 3e-14 52.6 0.9 5.7e-14 51.7 0.1 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF75170.1 - 3.8e-09 36.2 0.7 5.3e-07 29.3 0.0 2.9 1 1 2 3 3 3 2 Alcohol dehydrogenase GroES-like domain Transferase PF02458.10 EXF75171.1 - 5.8e-24 84.3 0.0 3.6e-18 65.2 0.0 2.6 2 1 0 2 2 2 2 Transferase family Condensation PF00668.15 EXF75171.1 - 0.063 12.1 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Condensation domain Herpes_TK_C PF08465.5 EXF75171.1 - 0.08 12.4 0.5 0.3 10.6 0.1 2.1 2 0 0 2 2 2 0 Thymidine kinase from Herpesvirus C-terminal PAN_3 PF08277.7 EXF75173.1 - 0.00017 21.1 2.0 0.0024 17.4 0.1 2.7 2 0 0 2 2 2 1 PAN-like domain PAN_4 PF14295.1 EXF75173.1 - 0.00028 20.5 8.5 0.00038 20.0 1.0 3.6 2 0 0 2 2 2 1 PAN domain MRP-S31 PF15433.1 EXF75173.1 - 4 6.7 14.3 5.3 6.3 9.9 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 TPR_14 PF13428.1 EXF75174.1 - 5.7e-06 26.5 3.5 6.2 7.7 0.1 5.9 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EXF75174.1 - 7.7e-05 22.1 0.0 0.13 12.0 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EXF75174.1 - 0.0024 18.1 4.1 2.1 8.7 0.0 4.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EXF75174.1 - 0.012 15.5 3.0 0.028 14.3 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EXF75174.1 - 0.028 15.0 6.2 1.5 9.5 0.1 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EXF75174.1 - 0.11 12.1 0.9 0.71 9.5 0.0 2.7 3 0 0 3 3 3 0 TPR repeat NAD_binding_6 PF08030.7 EXF75175.1 - 7.4e-20 71.4 0.0 1.4e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EXF75175.1 - 9.2e-14 51.6 8.0 9.2e-14 51.6 5.5 2.4 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EXF75175.1 - 2.5e-12 46.5 0.0 3.6e-11 42.8 0.0 2.2 2 0 0 2 2 2 1 FAD-binding domain NAD_binding_1 PF00175.16 EXF75175.1 - 0.00024 21.6 0.0 0.29 11.7 0.0 2.5 1 1 1 2 2 2 2 Oxidoreductase NAD-binding domain MFS_1 PF07690.11 EXF75176.1 - 7.1e-25 87.4 28.6 5.1e-18 64.9 8.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF75176.1 - 2.6e-09 36.1 17.6 4.5e-09 35.3 12.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF75177.1 - 4.4e-41 140.7 26.0 6.3e-41 140.2 18.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 EXF75178.1 - 2.3e-17 62.7 0.0 3.9e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAA_hydrolase PF01557.13 EXF75180.1 - 2.3e-61 207.0 0.0 3.1e-61 206.6 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DnaJ PF00226.26 EXF75181.1 - 0.00031 20.4 0.0 0.03 14.0 0.0 2.4 2 0 0 2 2 2 2 DnaJ domain zf-B_box PF00643.19 EXF75181.1 - 0.0073 16.1 5.8 0.018 14.9 4.0 1.6 1 0 0 1 1 1 1 B-box zinc finger Fungal_trans PF04082.13 EXF75182.1 - 1.1e-20 73.5 2.3 1.4e-20 73.3 0.6 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain BTB PF00651.26 EXF75183.1 - 5.6e-06 26.3 0.0 1.5e-05 24.9 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain GXWXG PF14231.1 EXF75183.1 - 0.14 11.7 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 GXWXG protein Nucleoplasmin PF03066.10 EXF75183.1 - 0.29 10.6 4.2 0.68 9.4 2.9 1.6 1 0 0 1 1 1 0 Nucleoplasmin p450 PF00067.17 EXF75184.1 - 7.1e-68 229.2 0.0 1.4e-63 215.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Ank PF00023.25 EXF75185.1 - 2e-16 58.8 0.2 2.8e-12 45.7 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EXF75185.1 - 2.5e-14 53.3 0.0 4e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EXF75185.1 - 2.6e-14 52.9 0.2 9.2e-11 41.6 0.1 2.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EXF75185.1 - 1.3e-13 50.9 0.4 1.9e-06 28.2 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF75185.1 - 1.1e-11 43.7 0.0 1.6e-08 33.9 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeat DUF3846 PF12957.2 EXF75185.1 - 0.087 12.5 0.1 1.1 9.0 0.0 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF3846) BTB PF00651.26 EXF75187.1 - 0.12 12.3 0.2 0.51 10.3 0.0 2.1 3 0 0 3 3 3 0 BTB/POZ domain adh_short PF00106.20 EXF75189.1 - 2.4e-33 115.4 3.2 3.4e-33 114.9 2.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF75189.1 - 1.8e-27 96.6 0.3 2.8e-27 96.0 0.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF75189.1 - 3.9e-18 65.7 1.4 5.4e-18 65.2 1.0 1.2 1 0 0 1 1 1 1 KR domain AdoHcyase_NAD PF00670.16 EXF75189.1 - 0.0055 16.5 0.8 0.0088 15.8 0.5 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain THF_DHG_CYH_C PF02882.14 EXF75189.1 - 0.0084 15.1 0.3 0.015 14.3 0.2 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 EXF75189.1 - 0.0092 15.6 1.0 0.015 14.9 0.7 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Gly_rich_SFCGS PF14272.1 EXF75189.1 - 0.038 13.8 1.3 0.074 12.9 0.3 2.0 2 0 0 2 2 2 0 Glycine-rich SFCGS 2-Hacid_dh_C PF02826.14 EXF75189.1 - 0.11 11.6 0.2 0.17 11.0 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Glycos_transf_2 PF00535.21 EXF75190.1 - 7.6e-35 120.0 0.0 9e-35 119.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EXF75190.1 - 4.5e-14 52.8 0.0 6.3e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EXF75190.1 - 1.9e-09 37.0 0.0 2.4e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EXF75190.1 - 1.1e-05 24.8 0.0 1.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF221 PF02714.10 EXF75192.1 - 1.5e-93 313.2 18.2 1.5e-93 313.2 12.6 1.6 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EXF75192.1 - 7.4e-41 139.3 1.6 1.8e-40 138.1 1.1 1.7 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EXF75192.1 - 1.1e-18 67.5 0.4 2.4e-18 66.3 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) AATase PF07247.7 EXF75193.1 - 2e-28 99.1 0.0 7.5e-27 94.0 0.0 2.7 1 1 0 1 1 1 1 Alcohol acetyltransferase WES_acyltransf PF03007.11 EXF75193.1 - 0.0063 16.1 0.2 0.29 10.6 0.1 2.8 2 1 0 2 2 2 1 Wax ester synthase-like Acyl-CoA acyltransferase domain Condensation PF00668.15 EXF75193.1 - 0.017 13.9 0.6 0.078 11.8 0.0 2.2 3 0 0 3 3 3 0 Condensation domain HAD_2 PF13419.1 EXF75195.1 - 8.7e-22 78.1 0.0 1.1e-21 77.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EXF75195.1 - 6e-13 49.7 0.1 1.1e-12 48.8 0.1 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EXF75195.1 - 5.8e-07 29.8 0.1 8.1e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EXF75195.1 - 0.003 17.2 0.0 0.0061 16.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.1 EXF75195.1 - 0.02 14.7 0.0 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase PTPS_related PF10131.4 EXF75195.1 - 0.077 11.1 0.0 0.086 10.9 0.0 1.1 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein DUF2226 PF09987.4 EXF75195.1 - 0.11 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2226) VacJ PF04333.8 EXF75195.1 - 0.17 11.3 0.1 0.36 10.2 0.0 1.5 1 0 0 1 1 1 0 VacJ like lipoprotein GFO_IDH_MocA PF01408.17 EXF75196.1 - 6.7e-17 62.1 0.0 1.4e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EXF75196.1 - 0.0087 16.4 0.1 0.019 15.3 0.1 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF1768 PF08719.6 EXF75197.1 - 1.5e-52 177.4 0.0 2.5e-52 176.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Tim44 PF04280.10 EXF75198.1 - 6.3e-35 120.3 0.0 2.4e-34 118.4 0.0 2.0 2 0 0 2 2 2 1 Tim44-like domain CDC45 PF02724.9 EXF75198.1 - 9.9 4.0 9.8 13 3.6 6.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Ribosomal_S11 PF00411.14 EXF75199.1 - 4.4e-10 39.7 0.0 7.5e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S11 Peptidase_C97 PF05903.9 EXF75200.1 - 2.7e-33 114.8 0.0 3.3e-33 114.5 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EXF75200.1 - 0.0033 17.3 0.0 0.0052 16.7 0.0 1.2 1 0 0 1 1 1 1 Lecithin retinol acyltransferase YchF-GTPase_C PF06071.8 EXF75201.1 - 2.4e-32 110.5 0.4 1.5e-31 108.0 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EXF75201.1 - 7.2e-12 45.2 0.0 2e-11 43.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase TPR_19 PF14559.1 EXF75201.1 - 8.6e-05 22.7 0.5 0.02 15.2 0.0 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat FeoB_N PF02421.13 EXF75201.1 - 0.0011 18.3 0.0 0.0021 17.3 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B TGS PF02824.16 EXF75201.1 - 0.002 17.8 0.0 0.006 16.3 0.0 1.8 1 0 0 1 1 1 1 TGS domain Rep_fac_C PF08542.6 EXF75201.1 - 0.0059 16.5 0.0 0.014 15.3 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain TPR_4 PF07721.9 EXF75201.1 - 0.04 14.3 7.6 1.6 9.3 1.7 4.3 3 0 0 3 3 3 0 Tetratricopeptide repeat BetaGal_dom3 PF13363.1 EXF75201.1 - 0.069 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Beta-galactosidase, domain 3 MobB PF03205.9 EXF75201.1 - 0.089 12.5 0.3 9.1 5.9 0.1 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EXF75201.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain TPR_2 PF07719.12 EXF75201.1 - 0.14 12.1 0.2 22 5.2 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat AAA_23 PF13476.1 EXF75201.1 - 0.31 11.3 3.3 1.4 9.1 2.2 2.0 1 1 0 1 1 1 0 AAA domain TPR_16 PF13432.1 EXF75201.1 - 6.1 7.6 12.7 16 6.2 1.3 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Peptidase_S8 PF00082.17 EXF75203.1 - 2.5e-26 92.4 0.9 4.2e-26 91.7 0.6 1.4 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EXF75203.1 - 4.3e-09 36.7 0.0 1e-08 35.5 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Ank_2 PF12796.2 EXF75204.1 - 4.3e-46 155.1 4.6 1.3e-12 47.8 0.1 6.7 3 1 4 7 7 7 6 Ankyrin repeats (3 copies) Ank PF00023.25 EXF75204.1 - 2.8e-41 137.3 0.0 7.7e-06 25.4 0.0 9.8 9 1 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.1 EXF75204.1 - 3.2e-31 106.6 1.2 4.1e-07 30.0 0.0 7.7 3 1 5 8 8 8 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 EXF75204.1 - 8.1e-28 96.2 0.7 0.0002 21.7 0.0 8.2 4 3 5 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF75204.1 - 5.9e-20 69.3 0.4 0.24 11.7 0.0 9.8 11 0 0 11 11 11 6 Ankyrin repeat MBOAT_2 PF13813.1 EXF75204.1 - 0.31 11.1 1.0 0.8 9.8 0.7 1.7 1 0 0 1 1 1 0 Membrane bound O-acyl transferase family WD40 PF00400.27 EXF75206.1 - 0.019 14.8 2.0 13 5.8 0.2 4.0 4 0 0 4 4 4 0 WD domain, G-beta repeat HlyIII PF03006.15 EXF75207.1 - 2.5e-61 206.9 17.3 3e-61 206.6 12.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related Yip1 PF04893.12 EXF75207.1 - 1.8 8.0 18.2 0.27 10.7 6.5 2.6 1 1 1 2 2 2 0 Yip1 domain TMA7 PF09072.5 EXF75208.1 - 2.3e-26 92.0 17.8 2.5e-26 91.9 12.4 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 EPL1 PF10513.4 EXF75208.1 - 0.079 13.1 0.0 0.086 13.0 0.0 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Pkinase PF00069.20 EXF75209.1 - 4.1e-29 101.5 0.1 1.7e-28 99.5 0.1 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF75209.1 - 6.1e-13 48.4 0.0 8.4e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase p450 PF00067.17 EXF75210.1 - 9.4e-50 169.4 0.0 1.6e-49 168.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Phage_T7_Capsid PF05396.6 EXF75210.1 - 0.054 13.6 0.0 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 Phage T7 capsid assembly protein CFEM PF05730.6 EXF75211.1 - 0.063 13.1 0.6 0.095 12.5 0.4 1.3 1 0 0 1 1 1 0 CFEM domain BPD_transp_2 PF02653.11 EXF75211.1 - 0.6 9.0 13.2 1.1 8.1 9.2 1.3 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component Lipase_GDSL PF00657.17 EXF75212.1 - 5.1e-14 52.6 0.4 6.9e-14 52.2 0.3 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EXF75212.1 - 3.6e-13 50.0 0.7 4.4e-13 49.7 0.5 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 EXF75212.1 - 3.9e-06 26.7 0.1 6.8e-06 25.9 0.0 1.4 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Raffinose_syn PF05691.7 EXF75212.1 - 0.1 10.1 0.0 0.13 9.7 0.0 1.1 1 0 0 1 1 1 0 Raffinose synthase or seed imbibition protein Sip1 Glyco_hydro_3 PF00933.16 EXF75213.1 - 7.3e-83 277.9 0.0 1e-82 277.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF75213.1 - 6.6e-49 166.4 0.0 4e-48 163.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF75213.1 - 2e-22 78.8 0.0 3.8e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF218 PF02698.12 EXF75214.1 - 3.3e-16 59.1 0.0 4.2e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 DUF218 domain Peptidase_M20 PF01546.23 EXF75215.1 - 1.2e-10 41.2 0.5 1.8e-10 40.6 0.4 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EXF75215.1 - 3.1e-07 30.1 0.0 1.4e-06 27.9 0.0 2.2 1 1 0 1 1 1 1 Peptidase dimerisation domain Fungal_trans_2 PF11951.3 EXF75216.1 - 6.2e-12 44.8 0.8 1.2e-11 43.8 0.5 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF75216.1 - 6.8e-09 35.4 9.6 1.2e-08 34.7 6.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EXF75217.1 - 1.1e-31 109.8 37.9 1.1e-31 109.8 26.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily ESSS PF10183.4 EXF75217.1 - 0.056 13.8 2.9 0.77 10.1 0.1 2.7 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF1228 PF06779.9 EXF75217.1 - 2.2 8.3 11.4 0.055 13.4 1.6 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1228) GtrA PF04138.9 EXF75217.1 - 3.5 7.6 16.5 1.8 8.5 0.1 4.6 3 2 1 4 4 4 0 GtrA-like protein DUF3425 PF11905.3 EXF75218.1 - 5.6e-31 107.2 0.7 1e-30 106.4 0.5 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Glyco_hydro_16 PF00722.16 EXF75219.1 - 2e-15 56.5 0.0 3.2e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DHH PF01368.15 EXF75219.1 - 0.00064 19.3 0.0 0.001 18.7 0.0 1.3 1 0 0 1 1 1 1 DHH family SKN1 PF03935.10 EXF75219.1 - 0.00085 17.5 0.8 0.047 11.8 1.2 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) CBM_5_12 PF02839.9 EXF75220.1 - 0.14 11.7 0.6 5.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Carbohydrate binding domain Mannosyl_trans2 PF04188.8 EXF75221.1 - 5.7e-65 219.9 9.1 6.8e-65 219.7 6.3 1.0 1 0 0 1 1 1 1 Mannosyltransferase (PIG-V)) PMT PF02366.13 EXF75221.1 - 0.00082 18.8 8.2 0.00082 18.8 5.6 2.2 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Phage_GPD PF05954.6 EXF75221.1 - 0.13 11.4 0.0 0.58 9.3 0.0 2.0 2 0 0 2 2 2 0 Phage late control gene D protein (GPD) SLAC1 PF03595.12 EXF75223.1 - 6.8e-78 261.6 47.0 7.8e-78 261.4 32.6 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Peptidase_M24 PF00557.19 EXF75224.1 - 4.9e-57 192.8 0.1 8.7e-57 192.0 0.1 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EXF75224.1 - 5.3e-22 77.6 0.0 1.1e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Zn_clus PF00172.13 EXF75225.1 - 0.00064 19.5 12.0 0.0012 18.7 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CHZ PF09649.5 EXF75225.1 - 0.039 13.1 0.0 0.039 13.1 0.0 2.3 3 0 0 3 3 3 0 Histone chaperone domain CHZ Cyclin_N PF00134.18 EXF75226.1 - 1.5e-42 144.1 0.2 3.2e-42 143.0 0.1 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EXF75226.1 - 3.1e-33 114.1 0.0 6.6e-33 113.1 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF2564 PF10819.3 EXF75226.1 - 0.048 13.7 0.0 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2564) TRAP_alpha PF03896.11 EXF75227.1 - 3.2e-09 36.1 0.0 5.5e-09 35.4 0.0 1.4 1 1 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF2874 PF11396.3 EXF75227.1 - 0.068 13.1 0.7 0.17 11.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2874) AT_hook PF02178.14 EXF75228.1 - 5.4e-06 25.4 45.0 0.011 15.3 2.9 6.1 5 1 1 6 6 6 4 AT hook motif Herpes_TAF50 PF03326.8 EXF75228.1 - 0.026 13.4 3.5 0.029 13.3 2.4 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Pro-rich PF15240.1 EXF75228.1 - 2.7 8.0 17.9 3.7 7.6 12.4 1.2 1 0 0 1 1 1 0 Proline-rich HIT PF01230.18 EXF75229.1 - 5.8e-17 62.0 0.4 1.1e-16 61.0 0.3 1.5 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EXF75229.1 - 3.1e-16 59.6 6.3 1.3e-15 57.6 4.3 1.9 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HA2 PF04408.18 EXF75230.1 - 5.4e-19 68.1 0.1 5.4e-19 68.1 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EXF75230.1 - 1.7e-15 56.8 0.0 3.6e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EXF75230.1 - 1e-14 54.1 0.0 2.2e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EXF75230.1 - 8.2e-10 38.4 0.2 3.8e-09 36.2 0.1 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase RWD PF05773.17 EXF75230.1 - 6e-06 26.1 0.0 1.3e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 RWD domain AAA_22 PF13401.1 EXF75230.1 - 4e-05 23.7 0.1 0.00015 21.8 0.1 2.0 1 0 0 1 1 1 1 AAA domain ResIII PF04851.10 EXF75230.1 - 0.00044 20.1 0.0 0.0011 18.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_29 PF13555.1 EXF75230.1 - 0.0029 17.0 0.0 0.0071 15.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain KaiC PF06745.8 EXF75230.1 - 0.0032 16.6 0.4 0.0076 15.3 0.0 1.8 2 0 0 2 2 2 1 KaiC UBA PF00627.26 EXF75230.1 - 0.0037 17.0 0.9 0.096 12.5 0.1 3.0 3 0 0 3 3 3 1 UBA/TS-N domain DND1_DSRM PF14709.1 EXF75230.1 - 0.008 16.4 1.2 0.019 15.2 0.1 2.1 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 T2SE PF00437.15 EXF75230.1 - 0.017 14.0 0.0 0.041 12.7 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.1 EXF75230.1 - 0.02 15.2 0.5 0.075 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EXF75230.1 - 0.022 14.1 0.0 0.058 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EXF75230.1 - 0.04 13.3 0.1 1.1 8.6 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EXF75230.1 - 0.048 13.1 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Bac_rhamnosid PF05592.6 EXF75231.1 - 2.4e-19 68.9 0.0 1.5e-18 66.3 0.0 2.0 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 EXF75231.1 - 0.0011 17.7 0.1 0.0019 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 GDE_C PF06202.9 EXF75231.1 - 0.077 11.6 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase GMC_oxred_C PF05199.8 EXF75232.1 - 3.2e-08 33.9 0.4 1.3e-07 31.9 0.1 2.1 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EXF75232.1 - 4.2e-06 26.1 0.0 2.7e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EXF75232.1 - 0.0013 17.7 0.3 0.037 12.9 0.0 3.2 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF75232.1 - 0.0082 16.1 0.2 0.03 14.3 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain PGAP1 PF07819.8 EXF75232.1 - 0.011 15.3 0.0 0.33 10.4 0.0 2.3 2 0 0 2 2 2 0 PGAP1-like protein FAD_binding_2 PF00890.19 EXF75232.1 - 0.018 13.8 0.1 0.034 12.9 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 EXF75232.1 - 0.055 13.3 0.1 0.055 13.3 0.1 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ELFV_dehydrog PF00208.16 EXF75234.1 - 2e-85 286.2 3.7 2.6e-85 285.9 2.6 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EXF75234.1 - 2.9e-49 165.9 0.0 7.1e-49 164.7 0.0 1.7 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.1 EXF75234.1 - 0.031 14.5 0.1 0.073 13.3 0.0 1.6 2 0 0 2 2 2 0 Putative NAD(P)-binding DNA_pol_B PF00136.16 EXF75235.1 - 8.1e-146 486.4 4.8 1.1e-145 485.9 3.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EXF75235.1 - 3.9e-80 269.1 0.4 1.2e-79 267.5 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EXF75235.1 - 6e-23 80.6 6.1 1.6e-22 79.2 4.2 1.8 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 EXF75235.1 - 7.1e-05 22.6 0.1 0.00039 20.2 0.1 2.4 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 EXF75235.1 - 0.0035 16.9 0.0 0.0074 15.8 0.0 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA_pol_B_2 PF03175.8 EXF75235.1 - 0.0069 15.1 0.9 0.084 11.5 0.0 2.4 2 0 0 2 2 2 1 DNA polymerase type B, organellar and viral C1_1 PF00130.17 EXF75235.1 - 0.02 14.6 0.9 0.02 14.6 0.7 2.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1948 PF09185.5 EXF75235.1 - 0.087 12.4 1.7 0.1 12.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1948) Rhomboid PF01694.17 EXF75236.1 - 1.9e-35 122.0 10.4 1.9e-35 122.0 7.2 2.6 3 0 0 3 3 3 1 Rhomboid family TAF1D PF15333.1 EXF75237.1 - 0.91 9.2 18.2 0.027 14.2 4.9 2.3 2 0 0 2 2 2 0 TATA box-binding protein-associated factor 1D RLL PF10036.4 EXF75237.1 - 2.1 7.6 10.7 0.074 12.4 2.9 1.9 2 0 0 2 2 2 0 Putative carnitine deficiency-associated protein Asparaginase PF00710.15 EXF75239.1 - 2.4e-100 335.4 0.0 4.9e-100 334.4 0.0 1.5 2 0 0 2 2 2 1 Asparaginase Ank_2 PF12796.2 EXF75239.1 - 2.6e-12 46.9 0.3 4.9e-12 46.0 0.2 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EXF75239.1 - 2.1e-09 37.6 0.3 6.8e-05 23.2 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EXF75239.1 - 1.3e-08 34.2 0.1 0.16 11.8 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EXF75239.1 - 3.9e-07 30.1 0.2 0.0011 19.1 0.2 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF75239.1 - 0.00042 20.2 0.1 1.6 9.2 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Pkinase PF00069.20 EXF75240.1 - 1.6e-62 210.9 0.0 2.4e-62 210.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF75240.1 - 1.5e-29 102.8 0.0 8e-29 100.4 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF75240.1 - 0.007 15.3 0.0 0.019 13.9 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Attacin_C PF03769.10 EXF75240.1 - 0.062 13.4 0.9 0.12 12.5 0.6 1.4 1 0 0 1 1 1 0 Attacin, C-terminal region UPF0542 PF15086.1 EXF75241.1 - 0.13 11.9 2.2 0.23 11.1 1.5 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 AMPKBI PF04739.10 EXF75242.1 - 8.6e-29 99.3 1.7 8.6e-29 99.3 1.2 1.9 2 0 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain Peptidase_M22 PF00814.20 EXF75243.1 - 4.4e-83 278.8 0.1 5.4e-83 278.5 0.0 1.1 1 0 0 1 1 1 1 Glycoprotease family EPL1 PF10513.4 EXF75244.1 - 6.6e-31 107.7 3.1 6.6e-31 107.7 2.2 2.9 3 1 0 3 3 3 2 Enhancer of polycomb-like EF-hand_1 PF00036.27 EXF75245.1 - 4.3e-26 88.1 13.5 4.9e-07 28.5 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EXF75245.1 - 2e-23 82.3 3.7 1.2e-12 47.7 0.6 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EXF75245.1 - 5.2e-20 69.4 6.3 4.7e-05 22.9 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EXF75245.1 - 3.4e-18 64.0 13.2 2.2e-06 26.7 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EXF75245.1 - 5.8e-15 54.6 13.5 2.4e-05 23.8 0.8 4.5 1 1 3 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EXF75245.1 - 4.9e-07 29.7 0.0 0.00028 20.8 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EXF75245.1 - 4.1e-06 26.4 8.2 0.0028 17.3 0.4 3.8 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EXF75245.1 - 0.039 13.8 0.1 1.7 8.5 0.0 3.0 2 1 1 3 3 3 0 EF-hand domain Ribosomal_S9 PF00380.14 EXF75249.1 - 6.9e-36 123.1 0.2 1.1e-35 122.4 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S9/S16 EF1G PF00647.14 EXF75250.1 - 7.8e-43 144.5 0.6 1.3e-42 143.8 0.4 1.3 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EXF75250.1 - 2.8e-14 52.8 0.0 8e-14 51.4 0.0 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EXF75250.1 - 2.2e-09 37.0 0.1 6.4e-09 35.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EXF75250.1 - 8.8e-09 35.4 0.0 2.6e-08 33.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EXF75250.1 - 3.1e-07 30.5 0.0 7.1e-07 29.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EXF75250.1 - 9.8e-06 25.9 0.0 2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NIF PF03031.13 EXF75251.1 - 5.5e-19 68.3 0.0 8.7e-19 67.7 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF947 PF06102.7 EXF75252.1 - 4.5e-55 186.0 30.1 4.5e-55 186.0 20.9 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF947) ABC1 PF03109.11 EXF75253.1 - 2.7e-32 111.2 0.0 4.9e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Es2 PF09751.4 EXF75254.1 - 3.9e-99 332.8 0.4 6.8e-99 332.0 0.3 1.4 1 1 0 1 1 1 1 Nuclear protein Es2 Metallophos PF00149.23 EXF75255.1 - 2.3e-38 131.6 0.1 3.7e-38 130.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EXF75255.1 - 6e-31 106.3 0.3 1.7e-30 104.9 0.1 1.9 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_11 PF13414.1 EXF75255.1 - 2.2e-25 88.0 1.8 3.2e-16 58.7 0.2 2.4 1 1 1 2 2 2 2 TPR repeat TPR_1 PF00515.23 EXF75255.1 - 6.3e-18 63.5 0.8 6.7e-05 22.3 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EXF75255.1 - 6e-13 47.6 0.3 0.012 15.4 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EXF75255.1 - 2.2e-07 30.5 2.5 0.011 15.8 0.0 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EXF75255.1 - 0.001 18.9 0.0 0.23 11.3 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EXF75255.1 - 0.0034 17.8 0.1 6.9 7.6 0.0 3.3 2 1 2 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EXF75255.1 - 0.0038 17.8 0.0 0.2 12.3 0.0 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EXF75255.1 - 0.0047 17.2 0.0 5 7.5 0.0 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EXF75255.1 - 0.031 14.2 0.0 5 7.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Spt4 PF06093.8 EXF75257.1 - 2.4e-33 113.8 0.3 3e-33 113.5 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Coronavirus_5 PF05528.6 EXF75257.1 - 0.074 12.8 0.7 0.26 11.1 0.5 2.0 1 1 0 1 1 1 0 Coronavirus gene 5 protein Cys_rich_CPXG PF14255.1 EXF75257.1 - 2 8.2 4.8 17 5.3 0.0 2.7 2 1 0 2 2 2 0 Cysteine-rich CPXCG Kin17_mid PF10357.4 EXF75258.1 - 1.9e-49 166.4 1.7 1.9e-49 166.4 1.2 1.9 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-C2H2_jaz PF12171.3 EXF75258.1 - 1.3e-05 25.1 2.4 2.8e-05 24.1 1.6 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EXF75258.1 - 2.1e-05 24.5 3.2 4.4e-05 23.5 2.2 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EXF75258.1 - 0.0094 16.0 0.8 0.0094 16.0 0.5 2.2 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) NOD PF06816.8 EXF75258.1 - 0.063 12.3 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 NOTCH protein Ecl1 PF12855.2 EXF75258.1 - 0.097 11.9 0.2 0.21 10.8 0.2 1.5 1 0 0 1 1 1 0 Life-span regulatory factor AA_kinase PF00696.23 EXF75259.1 - 1.2e-34 119.9 0.0 2.5e-34 118.9 0.0 1.6 1 1 0 1 1 1 1 Amino acid kinase family ACT PF01842.20 EXF75259.1 - 1.5e-14 53.1 1.3 2.9e-09 36.2 0.1 2.5 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.1 EXF75259.1 - 4.7e-14 51.6 4.0 1.4e-09 37.3 0.1 2.5 2 0 0 2 2 2 2 ACT domain SapB_1 PF05184.10 EXF75259.1 - 0.04 13.7 0.2 0.1 12.4 0.1 1.7 1 0 0 1 1 1 0 Saposin-like type B, region 1 RFX_DNA_binding PF02257.10 EXF75260.1 - 5.6e-29 100.1 0.1 1.3e-28 98.9 0.1 1.6 1 0 0 1 1 1 1 RFX DNA-binding domain TB2_DP1_HVA22 PF03134.14 EXF75261.1 - 5.5e-32 109.3 6.0 7.7e-32 108.9 4.1 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Mid1 PF12929.2 EXF75262.1 - 8.3e-127 423.4 5.8 9.8e-127 423.2 4.0 1.0 1 0 0 1 1 1 1 Stretch-activated Ca2+-permeable channel component DUF3280 PF11684.3 EXF75262.1 - 0.075 13.2 0.3 0.14 12.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2380) Fz PF01392.17 EXF75262.1 - 2.3 8.6 7.3 1.5 9.2 2.1 2.4 2 1 0 2 2 2 0 Fz domain Rpr2 PF04032.11 EXF75263.1 - 0.094 12.5 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain RAMP4 PF06624.7 EXF75264.1 - 1.3e-05 24.5 0.4 1.9e-05 24.0 0.3 1.3 1 1 0 1 1 1 1 Ribosome associated membrane protein RAMP4 DUF4083 PF13314.1 EXF75264.1 - 0.22 11.3 0.7 0.41 10.5 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) SMAP PF15477.1 EXF75265.1 - 3.3e-18 65.6 6.1 3.3e-18 65.6 4.2 6.8 3 2 0 4 4 4 1 Small acidic protein family Methyltransf_23 PF13489.1 EXF75266.1 - 1.5e-13 50.7 0.0 1.1e-12 47.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF75266.1 - 1e-11 45.1 0.0 2.1e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF75266.1 - 3.9e-07 30.6 0.0 2.3e-06 28.1 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF75266.1 - 1.5e-06 28.5 0.0 3.9e-06 27.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF75266.1 - 6e-06 25.9 0.0 4e-05 23.2 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF75266.1 - 0.0011 19.2 0.0 0.0027 18.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF75266.1 - 0.0014 18.6 0.0 0.0032 17.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.11 EXF75266.1 - 0.0019 16.6 0.0 0.003 15.9 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.13 EXF75266.1 - 0.0035 16.4 0.0 0.013 14.6 0.0 1.9 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EXF75266.1 - 0.005 15.9 0.0 0.01 14.8 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase YqeY PF09424.5 EXF75267.1 - 1.4e-24 86.5 8.2 1.8e-24 86.1 5.7 1.1 1 0 0 1 1 1 1 Yqey-like protein LANC_like PF05147.8 EXF75267.1 - 0.11 10.9 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein Spc97_Spc98 PF04130.8 EXF75268.1 - 4.2e-130 434.6 1.3 5.9e-130 434.1 0.9 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF1777 PF08648.7 EXF75268.1 - 0.037 13.7 35.4 0.1 12.3 24.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) MIP-T3 PF10243.4 EXF75268.1 - 0.51 8.7 23.3 0.76 8.1 16.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Proteasome PF00227.21 EXF75269.1 - 2.1e-56 190.2 0.1 2.7e-56 189.8 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EXF75269.1 - 1.6e-12 46.5 0.0 3.1e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF3137 PF11335.3 EXF75269.1 - 0.0031 17.1 0.1 0.1 12.2 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3137) Fungal_trans_2 PF11951.3 EXF75270.1 - 8.2e-17 60.8 1.1 2.7e-11 42.7 0.1 3.1 3 0 0 3 3 3 3 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF75270.1 - 2.9e-08 33.4 11.5 4.9e-08 32.7 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF75270.1 - 0.0017 17.2 6.5 0.0038 16.1 1.9 2.7 2 1 0 2 2 2 1 Fungal specific transcription factor domain Methyltransf_8 PF05148.10 EXF75271.1 - 5.4e-58 196.1 0.0 1.1e-56 191.9 0.0 2.7 3 0 0 3 3 3 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EXF75271.1 - 4.8e-06 26.9 0.0 1.4e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF75271.1 - 0.0024 17.4 0.1 0.46 10.0 0.0 2.4 1 1 0 2 2 2 2 Methyltransferase domain MTS PF05175.9 EXF75271.1 - 0.036 13.4 0.0 2.8 7.2 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase small domain MIP-T3 PF10243.4 EXF75271.1 - 0.064 11.7 40.1 0.0085 14.6 23.3 2.1 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Methyltransf_32 PF13679.1 EXF75271.1 - 0.15 11.7 0.0 0.15 11.7 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain Nop14 PF04147.7 EXF75271.1 - 0.94 7.3 27.2 1.7 6.4 18.9 1.3 1 0 0 1 1 1 0 Nop14-like family Asp_protease PF09668.5 EXF75272.1 - 1.9e-60 201.8 0.4 3e-60 201.2 0.3 1.3 1 0 0 1 1 1 1 Aspartyl protease Asp_protease_2 PF13650.1 EXF75272.1 - 5.2e-12 46.0 0.0 1.1e-11 45.0 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease ubiquitin PF00240.18 EXF75272.1 - 9.3e-10 37.7 0.1 2e-09 36.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EXF75272.1 - 9.4e-09 34.8 0.0 2.6e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain gag-asp_proteas PF13975.1 EXF75272.1 - 7.3e-08 32.1 0.1 2e-07 30.7 0.0 1.7 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP_2 PF08284.6 EXF75272.1 - 1.1e-06 28.6 0.0 1.8e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Retroviral aspartyl protease RVP PF00077.15 EXF75272.1 - 8.2e-06 25.6 0.0 2.1e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 Retroviral aspartyl protease Rad60-SLD PF11976.3 EXF75272.1 - 0.0011 18.5 0.5 0.0024 17.5 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like YukD PF08817.5 EXF75272.1 - 0.004 17.6 0.1 0.012 16.1 0.1 1.9 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD CUE PF02845.11 EXF75272.1 - 0.011 15.1 0.0 0.64 9.5 0.0 2.9 3 0 0 3 3 3 0 CUE domain Acetyltransf_1 PF00583.19 EXF75273.1 - 7.5e-09 35.4 0.0 1.2e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF75273.1 - 3.2e-07 30.4 0.0 5.9e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pribosyltran PF00156.22 EXF75274.1 - 4.3e-16 58.7 0.4 9.3e-16 57.6 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EXF75274.1 - 0.083 12.0 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase NOGCT PF08155.6 EXF75275.1 - 1.1e-28 98.6 1.4 2.3e-28 97.6 0.9 1.6 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.9 EXF75275.1 - 1.6e-26 91.9 2.8 1.6e-26 91.9 0.8 2.0 2 0 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EXF75275.1 - 1.3e-13 50.9 0.0 2.7e-13 49.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EXF75275.1 - 2.4e-08 33.4 0.0 4.4e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EXF75275.1 - 0.0015 17.6 0.1 0.0026 16.9 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EXF75275.1 - 0.016 15.7 0.1 0.06 13.8 0.0 2.1 2 0 0 2 2 2 0 Miro-like protein GTP_EFTU PF00009.22 EXF75275.1 - 0.024 14.0 0.4 0.13 11.6 0.2 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EXF75275.1 - 0.069 13.9 0.3 6.3 7.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.18 EXF75275.1 - 3.4 7.4 7.9 2.8 7.7 0.0 3.0 4 0 0 4 4 4 0 Dynamin family GDI PF00996.13 EXF75276.1 - 1.2e-184 613.7 0.0 1.4e-184 613.5 0.0 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor NAD_binding_8 PF13450.1 EXF75276.1 - 0.023 14.7 0.1 0.057 13.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain MRP-L47 PF06984.8 EXF75277.1 - 5.6e-24 83.8 0.5 1.1e-23 82.9 0.3 1.5 1 0 0 1 1 1 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) G-gamma PF00631.17 EXF75278.1 - 1.4e-26 92.0 0.0 2.5e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 GGL domain Dicty_REP PF05086.7 EXF75278.1 - 0.056 11.2 4.8 0.07 10.8 3.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Peptidase_S64 PF08192.6 EXF75278.1 - 0.52 8.5 2.8 0.62 8.3 2.0 1.0 1 0 0 1 1 1 0 Peptidase family S64 Herpes_BLLF1 PF05109.8 EXF75278.1 - 6 4.6 12.4 7.5 4.3 8.6 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) PCI PF01399.22 EXF75280.1 - 1.9e-08 34.5 0.5 1.1e-07 32.1 0.0 2.5 2 0 0 2 2 2 1 PCI domain STAS PF01740.16 EXF75280.1 - 0.031 13.6 0.1 0.079 12.3 0.0 1.6 1 0 0 1 1 1 0 STAS domain PROL5-SMR PF15621.1 EXF75281.1 - 1.4 9.4 4.7 3.2 8.2 3.4 1.6 1 1 1 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family WSC PF01822.14 EXF75282.1 - 2e-34 117.3 35.2 2.1e-18 66.0 9.6 5.6 4 1 2 6 6 6 2 WSC domain DUF605 PF04652.11 EXF75282.1 - 7 5.9 14.4 0.31 10.3 5.1 1.9 2 0 0 2 2 2 0 Vta1 like Stm1_N PF09598.5 EXF75283.1 - 1.9e-12 47.6 3.7 1.9e-12 47.6 2.5 4.5 3 2 2 5 5 5 1 Stm1 HABP4_PAI-RBP1 PF04774.10 EXF75283.1 - 0.0015 18.9 9.0 0.0015 18.9 6.3 2.7 3 0 0 3 3 3 1 Hyaluronan / mRNA binding family MFS_1 PF07690.11 EXF75285.1 - 3.7e-21 75.2 33.0 3.4e-11 42.4 5.3 3.1 3 0 0 3 3 3 3 Major Facilitator Superfamily MFS_2 PF13347.1 EXF75285.1 - 1.4e-08 33.5 8.1 0.00023 19.7 2.6 2.7 3 1 0 3 3 3 2 MFS/sugar transport protein DUF4022 PF13214.1 EXF75285.1 - 0.021 14.9 1.6 0.19 11.8 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4022) TraL PF07178.6 EXF75285.1 - 0.32 11.0 5.1 2.5 8.1 0.0 3.3 3 0 0 3 3 3 0 TraL protein LacY_symp PF01306.14 EXF75285.1 - 2.7 6.4 12.0 0.083 11.4 3.5 2.0 2 0 0 2 2 2 0 LacY proton/sugar symporter Actin PF00022.14 EXF75286.1 - 5.3e-29 100.8 0.0 3.3e-19 68.5 0.0 2.7 2 1 0 2 2 2 2 Actin MreB_Mbl PF06723.8 EXF75286.1 - 0.06 11.9 0.0 0.17 10.4 0.0 1.6 2 0 0 2 2 2 0 MreB/Mbl protein DUF4451 PF14616.1 EXF75289.1 - 5.9e-35 119.7 0.4 5.9e-35 119.7 0.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4451) LRR_8 PF13855.1 EXF75290.1 - 0.0042 16.8 0.1 3.6 7.4 0.0 2.9 3 0 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 EXF75290.1 - 0.094 12.3 0.1 2.1 8.0 0.0 2.5 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) GCK PF07802.6 EXF75290.1 - 0.19 11.8 1.7 0.85 9.7 0.1 2.1 2 0 0 2 2 2 0 GCK domain DUF2961 PF11175.3 EXF75291.1 - 3.4e-61 206.5 2.0 4.1e-57 193.2 1.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2961) Aldo_ket_red PF00248.16 EXF75294.1 - 2.5e-59 200.4 0.0 3.1e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HET PF06985.6 EXF75295.1 - 4.6e-24 85.1 0.0 8.3e-24 84.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 EXF75296.1 - 1.3e-09 38.2 0.0 5.8e-09 36.1 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EXF75296.1 - 1.3e-08 35.0 0.0 7.3e-06 26.3 0.1 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EXF75296.1 - 1.1e-07 31.2 2.0 0.01 15.5 0.0 4.2 5 1 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.1 EXF75296.1 - 8.1e-07 28.7 0.1 0.017 15.3 0.0 3.7 4 1 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EXF75296.1 - 4.6e-06 26.7 0.0 0.36 11.1 0.0 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Vesiculo_matrix PF06326.7 EXF75296.1 - 0.28 10.6 1.0 0.44 9.9 0.7 1.2 1 0 0 1 1 1 0 Vesiculovirus matrix protein TFIIS_C PF01096.13 EXF75297.1 - 2.1e-21 75.2 2.3 2.1e-21 75.2 1.6 2.6 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EXF75297.1 - 2.9e-06 26.8 2.3 1.2e-05 24.8 0.2 2.4 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.2 EXF75297.1 - 0.00063 19.4 4.3 0.082 12.7 0.2 2.4 2 1 0 2 2 2 2 Transposase zinc-ribbon domain Desulfoferrod_N PF06397.7 EXF75297.1 - 0.016 14.5 0.6 0.14 11.5 0.1 2.3 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DZR PF12773.2 EXF75297.1 - 0.84 9.5 6.6 2.8 7.8 0.1 2.5 2 1 0 2 2 2 0 Double zinc ribbon Zn_ribbon_recom PF13408.1 EXF75297.1 - 0.87 9.8 0.1 0.87 9.8 0.1 2.3 3 0 0 3 3 3 0 Recombinase zinc beta ribbon domain IBR PF01485.16 EXF75297.1 - 2 8.3 9.1 10 6.1 0.2 3.0 2 1 0 2 2 2 0 IBR domain zf-ribbon_3 PF13248.1 EXF75297.1 - 2.6 7.3 9.0 2.4 7.4 1.9 2.8 2 1 0 2 2 2 0 zinc-ribbon domain zf-TFIIB PF13453.1 EXF75297.1 - 3.5 6.8 9.3 0.86 8.8 0.5 2.7 2 1 0 2 2 2 0 Transcription factor zinc-finger zinc_ribbon_4 PF13717.1 EXF75297.1 - 6.2 6.6 9.8 28 4.4 0.0 3.8 4 0 0 4 4 4 0 zinc-ribbon domain Med31 PF05669.7 EXF75298.1 - 2.2e-31 107.6 0.5 1.8e-30 104.7 0.1 1.9 2 0 0 2 2 2 1 SOH1 SIP1 PF04938.7 EXF75299.1 - 0.016 14.6 0.1 15 4.8 0.0 3.2 3 0 0 3 3 3 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF2502 PF10697.4 EXF75299.1 - 5.6 7.1 11.7 0.1 12.6 1.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2502) RNR_inhib PF08591.5 EXF75300.1 - 5.3e-24 84.9 0.3 1e-23 84.0 0.2 1.5 1 0 0 1 1 1 1 Ribonucleotide reductase inhibitor Ribosomal_S27e PF01667.12 EXF75301.1 - 2.9e-28 97.1 7.4 3.9e-28 96.7 5.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 IBR PF01485.16 EXF75301.1 - 0.016 15.0 1.4 0.018 14.8 1.0 1.2 1 0 0 1 1 1 0 IBR domain TF_Zn_Ribbon PF08271.7 EXF75301.1 - 0.38 10.1 3.3 0.53 9.6 2.3 1.2 1 0 0 1 1 1 0 TFIIB zinc-binding Phosducin PF02114.11 EXF75302.1 - 2.1e-14 52.8 0.2 3.3e-14 52.2 0.1 1.2 1 0 0 1 1 1 1 Phosducin Thioredoxin PF00085.15 EXF75302.1 - 0.015 14.9 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin DUF3503 PF12011.3 EXF75302.1 - 0.063 13.0 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3503) LRR_4 PF12799.2 EXF75303.1 - 6.4e-15 54.3 5.5 9.6e-09 34.6 0.1 3.7 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EXF75303.1 - 4.6e-11 42.2 1.7 4.8e-08 32.6 0.1 3.5 2 1 1 3 3 3 2 Leucine rich repeat LRR_1 PF00560.28 EXF75303.1 - 4.6e-08 32.0 1.6 0.1 12.6 0.0 5.3 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_7 PF13504.1 EXF75303.1 - 0.011 15.7 11.5 0.13 12.5 0.1 4.9 5 0 0 5 5 5 0 Leucine rich repeat RTC PF01137.16 EXF75304.1 - 1.2e-39 135.4 0.2 3.6e-28 97.8 0.0 2.1 2 0 0 2 2 2 2 RNA 3'-terminal phosphate cyclase AhpC-TSA PF00578.16 EXF75306.1 - 1.7e-38 131.0 0.0 2.2e-38 130.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EXF75306.1 - 1.3e-12 47.5 0.0 1.7e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EXF75306.1 - 3.2e-11 42.6 0.0 5.9e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin MMtag PF10159.4 EXF75307.1 - 0.11 12.5 4.8 0.23 11.5 0.2 2.2 2 0 0 2 2 2 0 Kinase phosphorylation protein adh_short PF00106.20 EXF75310.1 - 2e-11 44.0 0.1 2.9e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF75310.1 - 2.2e-06 27.4 0.0 4.1e-06 26.5 0.0 1.4 2 0 0 2 2 2 1 KR domain NmrA PF05368.8 EXF75310.1 - 3.3e-06 26.5 0.9 4.9e-06 25.9 0.6 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF75310.1 - 0.00019 21.5 1.2 0.00028 20.9 0.4 1.6 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EXF75310.1 - 0.0073 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EXF75310.1 - 0.016 15.6 0.1 0.04 14.3 0.0 1.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.15 EXF75310.1 - 0.074 12.9 0.2 1 9.2 0.2 2.1 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus MFS_1 PF07690.11 EXF75311.1 - 4.5e-26 91.4 18.2 4.5e-26 91.4 12.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF75311.1 - 7.2e-09 34.7 0.2 7.2e-09 34.7 0.1 3.5 3 1 0 3 3 3 2 Sugar (and other) transporter DUF2263 PF10021.4 EXF75312.1 - 4.2e-19 69.0 0.0 7.6e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Macro PF01661.16 EXF75312.1 - 0.0024 17.7 0.0 0.028 14.3 0.0 2.3 2 0 0 2 2 2 1 Macro domain DUF735 PF05246.6 EXF75312.1 - 0.15 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF735) EcKinase PF02958.15 EXF75313.1 - 1.8e-18 66.7 0.0 3.4e-18 65.8 0.0 1.4 1 1 0 1 1 1 1 Ecdysteroid kinase APH PF01636.18 EXF75313.1 - 2.4e-08 33.9 0.1 9.8e-08 32.0 0.0 1.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EXF75313.1 - 0.0018 17.8 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Hydrophobin PF01185.13 EXF75315.1 - 6.3e-12 45.7 11.2 8.9e-12 45.2 7.8 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Transferase PF02458.10 EXF75316.1 - 5.2e-10 38.3 0.0 1.7e-09 36.6 0.0 1.7 1 1 0 1 1 1 1 Transferase family DUF3433 PF11915.3 EXF75318.1 - 8e-22 77.2 23.9 2.3e-16 59.7 2.1 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) Abhydrolase_3 PF07859.8 EXF75319.1 - 4.2e-12 46.1 1.2 8.7e-11 41.7 0.8 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF75319.1 - 2.3e-09 37.1 0.1 3.3e-09 36.6 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF75319.1 - 4.9e-09 35.7 0.0 4.3e-08 32.6 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EXF75319.1 - 1.8e-08 34.5 6.1 4.1e-07 30.1 4.3 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EXF75319.1 - 1.8e-07 30.6 0.0 3.6e-05 23.1 0.0 2.9 2 1 1 3 3 3 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.15 EXF75319.1 - 0.0014 18.2 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold LIP PF03583.9 EXF75319.1 - 0.01 15.0 0.2 0.11 11.6 0.0 2.0 2 0 0 2 2 2 0 Secretory lipase adh_short PF00106.20 EXF75319.1 - 0.011 15.7 0.2 0.02 14.8 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Esterase_phd PF10503.4 EXF75319.1 - 0.012 14.9 0.3 0.13 11.5 0.2 2.0 1 1 0 1 1 1 0 Esterase PHB depolymerase DUF2048 PF09752.4 EXF75319.1 - 0.023 13.5 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) KR PF08659.5 EXF75319.1 - 0.049 13.2 0.1 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 KR domain DUF829 PF05705.9 EXF75319.1 - 0.053 13.2 0.0 0.078 12.6 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) Glyco_trans_4_4 PF13579.1 EXF75319.1 - 0.094 12.8 3.2 5.5 7.0 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain YjeF_N PF03853.10 EXF75319.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus Fungal_trans PF04082.13 EXF75320.1 - 4.8e-17 61.6 0.1 1.1e-16 60.5 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF75320.1 - 9.2e-07 28.6 14.4 1.5e-06 27.9 10.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FlxA PF14282.1 EXF75320.1 - 3.7 7.5 11.5 0.074 12.9 1.2 2.5 3 0 0 3 3 3 0 FlxA-like protein p450 PF00067.17 EXF75321.1 - 1.4e-69 234.7 0.0 1.6e-69 234.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HSP70 PF00012.15 EXF75322.1 - 1.2e-57 195.2 0.0 1.4e-30 105.8 0.0 2.2 2 1 0 2 2 2 2 Hsp70 protein MreB_Mbl PF06723.8 EXF75322.1 - 1.7e-06 26.9 0.0 2.4e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein DUF4366 PF14283.1 EXF75324.1 - 0.0073 15.7 0.1 0.013 14.9 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) p450 PF00067.17 EXF75325.1 - 3.6e-64 216.9 0.0 4.6e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_76 PF03663.9 EXF75326.1 - 1.7e-148 494.9 18.7 2.2e-148 494.5 12.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Synaptobrevin PF00957.16 EXF75327.1 - 1.3e-33 114.4 1.1 1.5e-33 114.2 0.7 1.1 1 0 0 1 1 1 1 Synaptobrevin DUF619 PF04768.8 EXF75328.1 - 2.1e-48 163.9 0.1 7.2e-48 162.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF619) Semialdhyde_dh PF01118.19 EXF75328.1 - 2e-28 99.1 0.0 5.6e-28 97.6 0.0 1.8 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EXF75328.1 - 4.8e-28 98.3 0.0 1.1e-27 97.1 0.0 1.6 1 0 0 1 1 1 1 Amino acid kinase family DapB_N PF01113.15 EXF75328.1 - 0.014 15.2 0.0 0.036 13.9 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 EXF75328.1 - 0.13 11.2 0.0 0.44 9.4 0.0 1.9 2 0 0 2 2 2 0 Saccharopine dehydrogenase HET PF06985.6 EXF75329.1 - 1e-21 77.5 4.9 1.3e-18 67.4 0.3 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF2682 PF10909.3 EXF75329.1 - 0.03 14.5 0.2 0.086 13.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2682) Fasciclin PF02469.17 EXF75330.1 - 2.3e-44 150.4 5.4 7.9e-23 80.8 0.1 2.1 2 0 0 2 2 2 2 Fasciclin domain Mit_KHE1 PF10173.4 EXF75331.1 - 0.047 13.5 0.1 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related DUF3176 PF11374.3 EXF75332.1 - 1.7e-30 105.1 1.4 1.7e-30 105.1 1.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Cellulase PF00150.13 EXF75333.1 - 2.3e-14 53.2 1.9 5.5e-14 52.0 1.3 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FAD_binding_4 PF01565.18 EXF75334.1 - 1.4e-21 76.3 1.9 2.6e-21 75.5 0.7 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EXF75334.1 - 3.3e-11 42.9 0.0 1.7e-10 40.6 0.0 2.1 2 0 0 2 2 2 1 Berberine and berberine like MMR_HSR1 PF01926.18 EXF75335.1 - 7.2e-08 32.3 0.0 1.1e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.1 EXF75335.1 - 7.5e-06 25.8 0.0 1.6e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AIG1 PF04548.11 EXF75335.1 - 1.1e-05 24.6 0.0 1.7e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 AIG1 family Septin PF00735.13 EXF75335.1 - 0.00011 21.3 0.0 0.00019 20.5 0.0 1.4 1 0 0 1 1 1 1 Septin AAA_16 PF13191.1 EXF75335.1 - 0.00015 21.8 0.0 0.0024 17.8 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EXF75335.1 - 0.00021 21.1 0.0 0.00031 20.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 EXF75335.1 - 0.00022 21.0 0.3 0.066 13.0 0.1 2.3 1 1 1 2 2 2 1 Dynamin family AAA_22 PF13401.1 EXF75335.1 - 0.00026 21.1 0.0 0.00077 19.6 0.0 1.8 2 1 0 2 2 1 1 AAA domain Miro PF08477.8 EXF75335.1 - 0.00043 20.7 0.0 0.00079 19.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein MobB PF03205.9 EXF75335.1 - 0.00073 19.2 0.0 0.0015 18.2 0.0 1.6 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EXF75335.1 - 0.0027 18.5 0.1 0.0082 16.9 0.0 1.9 2 1 0 2 2 1 1 AAA domain ABC_tran PF00005.22 EXF75335.1 - 0.003 17.8 0.0 0.004 17.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA PF00004.24 EXF75335.1 - 0.0043 17.2 0.0 0.0067 16.6 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 EXF75335.1 - 0.0045 16.2 0.0 0.006 15.8 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 EXF75335.1 - 0.0079 15.9 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EXF75335.1 - 0.0081 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 NACHT domain DUF258 PF03193.11 EXF75335.1 - 0.011 14.9 0.0 0.019 14.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 PRK PF00485.13 EXF75335.1 - 0.011 15.2 0.0 0.059 12.9 0.0 2.2 2 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family FeoB_N PF02421.13 EXF75335.1 - 0.018 14.3 0.0 0.029 13.6 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B ATP_bind_1 PF03029.12 EXF75335.1 - 0.022 14.3 0.2 0.083 12.4 0.0 1.9 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_28 PF13521.1 EXF75335.1 - 0.026 14.4 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain tRNA_lig_kinase PF08303.6 EXF75335.1 - 0.029 14.2 0.0 0.053 13.3 0.0 1.4 1 0 0 1 1 1 0 tRNA ligase kinase domain PduV-EutP PF10662.4 EXF75335.1 - 0.054 12.9 0.0 0.15 11.5 0.0 1.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 EXF75335.1 - 0.054 12.9 0.0 1.3 8.4 0.0 2.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain Ras PF00071.17 EXF75335.1 - 0.059 12.7 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 Ras family AAA_24 PF13479.1 EXF75335.1 - 0.061 12.9 0.0 0.081 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.13 EXF75335.1 - 0.064 12.7 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Rad17 PF03215.10 EXF75335.1 - 0.089 11.4 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 EXF75335.1 - 0.097 12.8 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase Mito_fiss_reg PF05308.6 EXF75335.1 - 0.21 10.9 3.6 0.31 10.3 2.5 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Metallophos PF00149.23 EXF75336.1 - 2.8e-08 33.4 1.0 2e-07 30.6 0.7 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EXF75336.1 - 3.1e-07 30.3 0.3 5.4e-07 29.5 0.2 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Daxx PF03344.10 EXF75336.1 - 0.0022 16.5 5.3 0.0022 16.5 3.7 1.9 2 0 0 2 2 2 1 Daxx Family CDC45 PF02724.9 EXF75336.1 - 7.8 4.3 14.1 0.02 12.9 2.4 1.9 2 0 0 2 2 2 0 CDC45-like protein Transaldolase PF00923.14 EXF75337.1 - 5.5e-94 314.5 1.7 6.3e-94 314.3 1.1 1.0 1 0 0 1 1 1 1 Transaldolase SNase PF00565.12 EXF75338.1 - 2.1e-74 246.6 3.3 4.2e-22 78.4 0.0 5.4 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EXF75338.1 - 2.8e-23 82.0 0.0 5.9e-23 81.0 0.0 1.5 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 EXF75338.1 - 9.4e-06 24.9 0.0 2.8e-05 23.3 0.0 1.7 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) DUF3334 PF11813.3 EXF75338.1 - 0.092 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3334) Sod_Cu PF00080.15 EXF75339.1 - 1.3e-43 148.6 6.9 1.5e-43 148.3 4.8 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CNH PF00780.17 EXF75340.1 - 7.9e-69 232.1 0.0 1.3e-68 231.4 0.0 1.2 1 0 0 1 1 1 1 CNH domain RhoGEF PF00621.15 EXF75340.1 - 1.8e-32 112.6 1.0 3.4e-32 111.7 0.7 1.5 1 0 0 1 1 1 1 RhoGEF domain PH_5 PF15405.1 EXF75340.1 - 5.1e-14 52.3 0.0 2.9e-13 49.9 0.0 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EXF75340.1 - 3.3e-05 24.0 0.0 9.6e-05 22.5 0.0 1.9 1 1 0 1 1 1 1 PH domain Beta-lactamase PF00144.19 EXF75341.1 - 5.8e-30 104.4 1.4 8.4e-30 103.9 1.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EXF75341.1 - 0.06 13.1 0.0 13 5.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3471) Pkinase PF00069.20 EXF75344.1 - 1.5e-38 132.4 0.0 1.9e-38 132.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF75344.1 - 9e-14 51.1 0.0 1.3e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EXF75344.1 - 1.5e-05 24.8 0.0 0.0015 18.3 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.6 EXF75344.1 - 0.057 12.2 0.1 0.087 11.6 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Exo_endo_phos PF03372.18 EXF75345.1 - 3.1e-14 53.5 0.2 9.9e-14 51.8 0.1 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.20 EXF75346.1 - 1.5e-65 220.9 0.0 1.8e-65 220.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF75346.1 - 4e-31 108.0 0.0 5.2e-31 107.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF75346.1 - 0.00015 20.8 0.0 0.00024 20.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EXF75346.1 - 0.003 17.3 0.1 0.0092 15.7 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EXF75346.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RabGAP-TBC PF00566.13 EXF75347.1 - 5.3e-47 160.0 0.0 8.8e-47 159.3 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.1 EXF75347.1 - 2e-06 27.2 2.1 0.0081 15.9 0.1 4.0 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 EXF75347.1 - 5.7e-06 26.3 1.6 0.00021 21.3 0.1 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EXF75347.1 - 0.00061 18.9 0.4 0.078 12.3 0.2 3.4 3 0 0 3 3 3 1 EF hand EF-hand_5 PF13202.1 EXF75347.1 - 0.014 14.7 0.9 0.057 12.7 0.6 2.1 1 0 0 1 1 1 0 EF hand WSC PF01822.14 EXF75348.1 - 7.1e-16 57.9 22.2 1.9e-11 43.7 0.8 5.7 5 2 0 5 5 5 3 WSC domain FAD_binding_4 PF01565.18 EXF75349.1 - 4.2e-20 71.6 1.5 6.8e-20 70.9 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.9 EXF75349.1 - 9.8e-13 48.2 0.8 6.7e-07 29.1 0.0 2.5 2 1 0 2 2 2 2 D-arabinono-1,4-lactone oxidase FAD-oxidase_C PF02913.14 EXF75349.1 - 0.041 13.2 0.0 3.9 6.7 0.0 2.4 2 0 0 2 2 2 0 FAD linked oxidases, C-terminal domain p450 PF00067.17 EXF75350.1 - 3.1e-50 171.0 0.0 3.8e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TAXi_C PF14541.1 EXF75350.1 - 0.025 14.1 0.0 0.043 13.3 0.0 1.3 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal adh_short PF00106.20 EXF75351.1 - 1.6e-09 37.8 0.0 2.6e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EXF75351.1 - 0.015 15.3 0.0 0.026 14.5 0.0 1.4 1 1 0 1 1 1 0 NADH(P)-binding KR PF08659.5 EXF75351.1 - 0.022 14.4 0.2 0.099 12.2 0.1 2.0 1 1 0 1 1 1 0 KR domain Pal1 PF08316.6 EXF75352.1 - 2.3e-43 147.9 1.3 7.6e-43 146.3 0.9 1.9 1 1 0 1 1 1 1 Pal1 cell morphology protein Fasciclin PF02469.17 EXF75354.1 - 1.3e-39 135.0 0.0 5.1e-20 71.7 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF3433 PF11915.3 EXF75356.1 - 2.1e-27 95.1 13.9 4.7e-24 84.3 1.8 3.8 5 0 0 5 5 5 2 Protein of unknown function (DUF3433) Ank_2 PF12796.2 EXF75360.1 - 2.9e-16 59.5 0.0 3.8e-06 27.1 0.0 3.7 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EXF75360.1 - 1.6e-11 43.4 1.5 0.002 17.8 0.0 5.5 6 0 0 6 6 6 2 Ankyrin repeat Ank_3 PF13606.1 EXF75360.1 - 4.6e-09 35.6 1.5 0.92 9.9 0.0 6.1 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 EXF75360.1 - 5.8e-09 35.9 1.6 0.49 10.7 0.0 5.0 4 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EXF75360.1 - 2.5e-05 24.6 0.2 2.4 8.7 0.0 4.4 4 0 0 4 4 4 1 Ankyrin repeats (many copies) HET PF06985.6 EXF75361.1 - 1.8e-11 44.3 0.0 5.2e-11 42.8 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aminotran_5 PF00266.14 EXF75362.1 - 6.2e-15 54.8 0.0 7.9e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V SLA_LP_auto_ag PF05889.8 EXF75362.1 - 0.0011 17.5 0.0 0.0015 17.0 0.0 1.1 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Aminotran_1_2 PF00155.16 EXF75362.1 - 0.0011 17.9 0.0 0.0066 15.4 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II Pyridoxal_deC PF00282.14 EXF75362.1 - 0.022 13.1 0.0 0.033 12.6 0.0 1.1 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain SAICAR_synt PF01259.13 EXF75363.1 - 1.4e-86 289.6 0.0 1.8e-86 289.3 0.0 1.0 1 0 0 1 1 1 1 SAICAR synthetase Asp PF00026.18 EXF75364.1 - 9.4e-67 225.4 5.9 1.3e-66 225.0 4.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EXF75364.1 - 6.3e-08 32.7 0.1 1.5e-07 31.5 0.1 1.7 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EXF75364.1 - 0.0004 20.8 3.1 0.81 10.2 1.3 3.5 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EXF75364.1 - 0.012 15.2 0.7 0.1 12.1 0.1 2.6 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EXF75364.1 - 0.038 13.7 0.0 3.4 7.5 0.0 2.6 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease Paramyxo_PNT PF13825.1 EXF75364.1 - 0.38 9.9 3.2 0.77 8.9 2.2 1.4 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus PHD PF00628.24 EXF75365.1 - 1.7e-12 46.8 5.9 5.3e-12 45.2 4.1 1.9 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EXF75365.1 - 0.097 12.0 1.0 0.23 10.7 0.7 1.7 1 0 0 1 1 1 0 PHD-finger PHD_3 PF13922.1 EXF75365.1 - 0.13 12.5 5.3 0.11 12.7 0.7 2.5 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx zf-RING_2 PF13639.1 EXF75365.1 - 1.7 8.5 5.7 4.2 7.2 4.0 1.6 1 0 0 1 1 1 0 Ring finger domain DUF3795 PF12675.2 EXF75365.1 - 3 8.0 8.9 0.54 10.4 3.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3795) SCO1-SenC PF02630.9 EXF75366.1 - 2.2e-60 203.2 0.0 3e-60 202.8 0.0 1.1 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.16 EXF75366.1 - 8.1e-08 32.0 0.0 1.5e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EXF75366.1 - 0.00021 21.3 0.0 0.00044 20.3 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EXF75366.1 - 0.0012 18.4 0.0 0.016 14.7 0.0 2.1 1 1 0 1 1 1 1 Redoxin Hydrolase_6 PF13344.1 EXF75367.1 - 2.7e-24 84.9 0.0 5e-24 84.1 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EXF75367.1 - 5.5e-16 58.0 0.0 2.2e-15 56.1 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.1 EXF75367.1 - 0.00039 20.6 0.1 0.048 13.8 0.0 3.3 2 2 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EXF75367.1 - 0.002 18.6 0.0 1.7 9.0 0.0 3.5 2 1 2 4 4 4 2 haloacid dehalogenase-like hydrolase Choline_kinase PF01633.15 EXF75368.1 - 1.2e-56 191.6 0.3 2.6e-55 187.2 0.0 2.3 2 0 0 2 2 2 1 Choline/ethanolamine kinase Choline_kin_N PF04428.9 EXF75368.1 - 4.2e-22 77.3 0.0 7.9e-22 76.4 0.0 1.5 1 0 0 1 1 1 1 Choline kinase N terminus APH PF01636.18 EXF75368.1 - 6e-06 26.1 0.0 6e-06 26.1 0.0 2.6 3 1 0 3 3 3 1 Phosphotransferase enzyme family Plasmodium_Vir PF05795.6 EXF75368.1 - 0.54 9.4 3.0 0.35 10.0 0.4 1.8 2 0 0 2 2 2 0 Plasmodium vivax Vir protein G-patch PF01585.18 EXF75369.1 - 5e-12 45.4 2.1 9.2e-12 44.5 1.5 1.5 1 0 0 1 1 1 1 G-patch domain RRM_6 PF14259.1 EXF75369.1 - 1.1e-09 38.1 0.0 0.00034 20.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EXF75369.1 - 2.6e-06 26.9 0.0 0.015 14.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch_2 PF12656.2 EXF75369.1 - 3e-06 26.9 0.6 1.3e-05 24.9 0.4 2.1 1 0 0 1 1 1 1 DExH-box splicing factor binding site zf-RanBP PF00641.13 EXF75369.1 - 3.3e-05 22.8 4.3 9.1e-05 21.4 3.0 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others RED_N PF07808.8 EXF75369.1 - 0.0053 16.0 1.9 0.0053 16.0 1.3 2.0 2 0 0 2 2 2 1 RED-like protein N-terminal region zf-C2H2_2 PF12756.2 EXF75369.1 - 0.0086 16.1 0.6 0.023 14.7 0.4 1.7 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) RRM_5 PF13893.1 EXF75369.1 - 0.021 14.6 0.2 6.4 6.7 0.1 2.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 EXF75369.1 - 0.14 11.9 3.7 0.1 12.3 0.5 2.1 2 0 0 2 2 2 0 Double zinc ribbon DUF2413 PF10310.4 EXF75369.1 - 9.5 4.9 8.8 20 3.8 6.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) MoaE PF02391.12 EXF75370.1 - 1.9e-30 105.0 0.0 2.4e-30 104.7 0.0 1.1 1 0 0 1 1 1 1 MoaE protein BTB PF00651.26 EXF75371.1 - 3.2e-24 85.0 0.9 1.7e-13 50.5 0.3 2.9 3 0 0 3 3 3 2 BTB/POZ domain Ank_2 PF12796.2 EXF75371.1 - 6.8e-05 23.1 0.0 0.00028 21.1 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EXF75371.1 - 0.00017 21.9 0.0 0.00044 20.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EXF75371.1 - 0.017 14.9 0.0 0.045 13.5 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeat Ank_3 PF13606.1 EXF75371.1 - 0.052 13.8 0.0 0.21 11.9 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeat Pkinase PF00069.20 EXF75372.1 - 2.3e-58 197.3 0.0 3.5e-58 196.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF75372.1 - 3.3e-37 127.9 0.0 1.9e-36 125.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF75372.1 - 0.00024 20.1 0.0 0.00067 18.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like CALCOCO1 PF07888.6 EXF75372.1 - 0.0011 17.4 6.1 0.0011 17.4 4.2 2.0 2 0 0 2 2 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like NCA2 PF08637.5 EXF75372.1 - 0.0072 15.2 0.0 0.024 13.5 0.0 1.8 2 0 0 2 2 2 1 ATP synthase regulation protein NCA2 APH PF01636.18 EXF75372.1 - 0.057 13.1 0.4 0.32 10.6 0.0 2.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family zf-C2H2 PF00096.21 EXF75373.1 - 7e-09 35.5 12.3 0.00034 20.7 1.5 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EXF75373.1 - 2.5e-07 30.6 9.2 9.2e-07 28.8 0.8 3.1 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EXF75373.1 - 4.6e-05 23.4 10.6 0.0084 16.3 1.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-met PF12874.2 EXF75373.1 - 0.015 15.5 3.4 0.034 14.3 1.0 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EXF75373.1 - 0.06 13.5 0.7 0.06 13.5 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EXF75373.1 - 4.2 7.2 8.2 11 5.8 0.7 2.4 1 1 1 2 2 2 0 BED zinc finger Lactonase PF10282.4 EXF75374.1 - 2.8e-24 85.8 1.2 9e-24 84.1 0.7 1.6 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller SGL PF08450.7 EXF75374.1 - 0.03 13.6 0.0 0.065 12.6 0.0 1.5 1 0 0 1 1 1 0 SMP-30/Gluconolaconase/LRE-like region Oxidored_FMN PF00724.15 EXF75376.1 - 2.5e-43 148.4 0.0 3.4e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family His_biosynth PF00977.16 EXF75376.1 - 0.0011 18.3 0.0 0.0016 17.7 0.0 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein Ecm33 PF12454.3 EXF75377.1 - 0.34 10.8 5.5 2.3 8.1 0.1 2.7 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein RTA1 PF04479.8 EXF75378.1 - 3.3e-33 115.0 6.5 4.4e-33 114.6 4.5 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF1691 PF07950.6 EXF75378.1 - 0.12 12.3 2.3 0.25 11.2 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1691) Whi5 PF08528.6 EXF75379.1 - 8.8e-07 28.3 0.2 1.5e-06 27.6 0.1 1.4 1 0 0 1 1 1 1 Whi5 like FERM_M PF00373.13 EXF75381.1 - 6.7 6.9 6.6 49 4.1 4.6 2.3 1 1 0 1 1 1 0 FERM central domain Peptidase_M18 PF02127.10 EXF75382.1 - 4.3e-167 555.9 0.0 1.3e-166 554.4 0.0 1.6 1 1 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EXF75382.1 - 7.9e-06 24.8 0.1 0.0014 17.5 0.0 2.7 3 0 0 3 3 3 2 M42 glutamyl aminopeptidase DUF3552 PF12072.3 EXF75383.1 - 0.059 12.5 7.8 0.073 12.2 5.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) GATA PF00320.22 EXF75383.1 - 0.14 11.5 4.1 0.31 10.4 2.9 1.6 1 0 0 1 1 1 0 GATA zinc finger DUF2264 PF10022.4 EXF75385.1 - 5.3e-127 423.4 0.6 6.9e-127 423.0 0.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) FH2 PF02181.18 EXF75386.1 - 1.6e-82 277.3 5.2 1.6e-82 277.3 3.6 1.9 2 0 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EXF75386.1 - 4.3e-65 218.6 0.2 1.8e-64 216.5 0.0 2.2 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EXF75386.1 - 4e-53 179.7 4.7 7e-53 178.9 1.7 2.6 2 1 1 3 3 3 1 Diaphanous FH3 Domain zf-RING_2 PF13639.1 EXF75387.1 - 3.8e-08 33.0 5.5 3.8e-08 33.0 3.8 2.6 3 0 0 3 3 3 1 Ring finger domain zf-rbx1 PF12678.2 EXF75387.1 - 3.6e-06 26.9 6.1 4.3e-06 26.7 2.7 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EXF75387.1 - 1.2e-05 25.1 0.5 1.2e-05 25.1 0.3 3.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EXF75387.1 - 1.4e-05 24.6 0.6 1.4e-05 24.6 0.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EXF75387.1 - 0.0029 17.3 2.9 0.0029 17.3 2.0 2.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-Apc11 PF12861.2 EXF75387.1 - 0.0031 17.3 4.5 0.0031 17.3 3.1 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EXF75387.1 - 0.19 11.6 0.2 0.19 11.6 0.2 3.0 4 0 0 4 4 4 0 zinc finger of C3HC4-type, RING NDUF_B12 PF08122.7 EXF75387.1 - 0.41 10.4 3.2 3.1 7.6 1.2 2.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B12 subunit family zf-RING_UBOX PF13445.1 EXF75387.1 - 2.2 8.0 8.9 0.14 11.8 1.0 2.9 2 1 0 2 2 2 0 RING-type zinc-finger Hus1 PF04005.7 EXF75388.1 - 1.1e-94 316.6 0.0 1.2e-94 316.5 0.0 1.0 1 0 0 1 1 1 1 Hus1-like protein MMtag PF10159.4 EXF75389.1 - 4.6e-28 97.0 9.1 4.6e-28 97.0 6.3 3.1 2 2 1 3 3 3 1 Kinase phosphorylation protein Med6 PF04934.9 EXF75390.1 - 4.9e-39 133.0 0.0 6.5e-39 132.6 0.0 1.2 1 0 0 1 1 1 1 MED6 mediator sub complex component PC-Esterase PF13839.1 EXF75390.1 - 0.094 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p NmrA PF05368.8 EXF75391.1 - 1.6e-16 60.2 0.0 3.6e-16 59.1 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EXF75391.1 - 2.1e-16 60.4 0.0 2e-15 57.2 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EXF75391.1 - 0.016 15.5 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EXF75391.1 - 0.039 13.3 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family KR PF08659.5 EXF75391.1 - 0.04 13.5 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 KR domain adh_short PF00106.20 EXF75392.1 - 1.2e-27 96.9 0.0 2.2e-27 95.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF75392.1 - 4.8e-15 55.9 0.0 3e-06 27.1 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF75392.1 - 3.8e-12 46.2 0.1 9.2e-12 44.9 0.0 1.8 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 EXF75392.1 - 0.0035 16.8 0.0 0.0084 15.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EXF75392.1 - 0.0076 15.1 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein ThiF PF00899.16 EXF75392.1 - 0.071 12.9 0.1 0.15 11.8 0.1 1.6 1 1 0 1 1 1 0 ThiF family HA2 PF04408.18 EXF75393.1 - 4.7e-20 71.5 0.0 1.6e-19 69.8 0.0 2.0 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EXF75393.1 - 4.4e-14 52.1 0.1 3.8e-13 49.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.11 EXF75393.1 - 2.2e-11 43.5 0.0 5.4e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EXF75393.1 - 8.2e-09 35.1 0.1 4.7e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EXF75393.1 - 9.6e-06 25.7 0.1 5.1e-05 23.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain SDA1 PF05285.7 EXF75393.1 - 0.0045 16.3 15.5 0.0045 16.3 10.8 3.3 3 1 0 3 3 2 1 SDA1 PhoH PF02562.11 EXF75393.1 - 0.012 14.8 0.1 0.033 13.4 0.0 1.7 2 0 0 2 2 2 0 PhoH-like protein T2SE PF00437.15 EXF75393.1 - 0.013 14.4 0.2 0.039 12.8 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein KaiC PF06745.8 EXF75393.1 - 0.035 13.2 1.1 0.056 12.5 0.1 1.8 2 0 0 2 2 2 0 KaiC ResIII PF04851.10 EXF75393.1 - 0.15 11.8 4.3 0.35 10.6 0.0 3.0 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 EXF75393.1 - 0.33 11.2 3.2 12 6.2 0.0 2.6 2 0 0 2 2 2 0 ABC transporter DUF2372 PF10178.4 EXF75394.1 - 0.0019 18.2 0.0 0.0033 17.5 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised conserved protein (DUF2372) CoA_transf_3 PF02515.12 EXF75395.1 - 2.4e-53 180.2 0.0 3.4e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 CoA-transferase family III Nudix_N PF12535.3 EXF75395.1 - 0.026 13.9 0.0 0.061 12.7 0.0 1.6 1 0 0 1 1 1 0 Hydrolase of X-linked nucleoside diphosphate N terminal adh_short PF00106.20 EXF75396.1 - 2.8e-16 59.8 0.7 4.2e-16 59.3 0.5 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF75396.1 - 2.3e-06 27.4 0.3 3.5e-06 26.8 0.2 1.4 1 1 0 1 1 1 1 KR domain Dynamin_M PF01031.15 EXF75397.1 - 1.1e-105 352.6 0.0 2.8e-105 351.3 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EXF75397.1 - 2.6e-56 190.0 0.0 4.7e-56 189.2 0.0 1.4 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EXF75397.1 - 1.7e-29 101.5 4.1 1.7e-29 101.5 2.8 2.0 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EXF75397.1 - 0.0001 22.1 0.2 0.0017 18.3 0.1 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EXF75397.1 - 0.0082 16.6 0.0 0.038 14.4 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein WD40 PF00400.27 EXF75398.1 - 6.7e-21 73.3 6.2 3.4e-07 29.8 0.1 7.3 6 1 0 6 6 6 5 WD domain, G-beta repeat CLTH PF10607.4 EXF75398.1 - 0.00016 21.3 0.1 0.00032 20.3 0.1 1.5 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Cytochrom_D1 PF02239.11 EXF75398.1 - 0.16 10.2 0.0 6.1 5.0 0.0 2.7 1 1 2 3 3 3 0 Cytochrome D1 heme domain Abhydrolase_2 PF02230.11 EXF75399.1 - 3.4e-10 39.7 0.0 3.6e-09 36.3 0.0 2.1 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EXF75399.1 - 0.00073 19.3 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF75399.1 - 0.00084 19.2 0.1 0.0011 18.9 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Atg14 PF10186.4 EXF75400.1 - 0.079 11.8 0.7 0.1 11.4 0.5 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 LCCL PF03815.14 EXF75402.1 - 1.9e-20 72.6 0.2 3e-20 71.9 0.1 1.3 1 0 0 1 1 1 1 LCCL domain AMP-binding PF00501.23 EXF75403.1 - 2.3e-76 256.8 0.0 3.4e-76 256.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EXF75403.1 - 2.1e-60 203.7 0.0 6.1e-60 202.2 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein adh_short PF00106.20 EXF75403.1 - 9.7e-39 132.9 5.3 1.8e-34 119.0 2.3 2.7 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EXF75403.1 - 2.5e-21 76.1 4.7 1.4e-16 60.6 1.6 2.5 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EXF75403.1 - 8.9e-19 68.2 0.3 8.9e-19 68.2 0.2 1.6 2 0 0 2 2 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EXF75403.1 - 6.1e-16 58.5 1.1 3.2e-09 36.5 0.0 3.4 3 1 0 3 3 3 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF75403.1 - 2.7e-11 43.8 1.1 1.3e-05 25.3 0.8 3.6 2 1 0 2 2 2 2 NADH(P)-binding PP-binding PF00550.20 EXF75403.1 - 8.2e-10 38.8 0.0 2.3e-09 37.3 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EXF75403.1 - 2.9e-07 29.4 0.9 0.00025 19.8 0.0 3.0 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EXF75403.1 - 4e-07 29.2 0.9 0.0022 16.9 0.0 4.0 4 0 0 4 4 4 1 RmlD substrate binding domain AMP-binding_C PF13193.1 EXF75403.1 - 1.8e-06 28.7 0.0 1.2e-05 26.1 0.0 2.5 2 0 0 2 2 1 1 AMP-binding enzyme C-terminal domain Polysacc_synt_2 PF02719.10 EXF75403.1 - 0.00012 21.0 0.9 0.26 10.1 0.0 3.2 3 1 0 3 3 3 2 Polysaccharide biosynthesis protein DFP PF04127.10 EXF75403.1 - 0.0041 16.7 0.9 0.0091 15.6 0.6 1.5 1 0 0 1 1 1 1 DNA / pantothenate metabolism flavoprotein NmrA PF05368.8 EXF75403.1 - 0.0052 16.0 2.9 1.5 8.0 0.0 2.6 2 0 0 2 2 2 2 NmrA-like family THF_DHG_CYH_C PF02882.14 EXF75403.1 - 0.0076 15.3 0.2 0.02 13.9 0.2 1.7 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EXF75403.1 - 0.13 12.0 2.1 0.34 10.7 1.4 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase TGT PF01702.13 EXF75404.1 - 5.9e-30 104.3 0.0 7.4e-30 103.9 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase NDUFA12 PF05071.11 EXF75405.1 - 4.4e-27 94.5 1.0 5.6e-27 94.2 0.7 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PLDc_2 PF13091.1 EXF75406.1 - 4e-14 52.4 0.0 1.4e-06 28.0 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EXF75406.1 - 8.7e-08 31.7 2.1 0.026 14.3 0.0 3.3 2 1 0 2 2 2 2 Phospholipase D Active site motif IF-2B PF01008.12 EXF75408.1 - 7.3e-47 159.6 0.0 1.8e-46 158.3 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family IF3_C PF00707.17 EXF75409.1 - 7.3e-13 48.0 0.5 1.4e-12 47.1 0.4 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain mIF3 PF14877.1 EXF75409.1 - 1.2e-06 28.0 1.3 2.2e-05 23.9 0.9 2.1 1 1 0 1 1 1 1 Mitochondrial translation initiation factor IF3_N PF05198.11 EXF75409.1 - 0.0063 16.4 1.7 0.032 14.1 0.1 2.7 2 1 0 2 2 2 1 Translation initiation factor IF-3, N-terminal domain CDC37_N PF03234.9 EXF75409.1 - 0.54 10.5 3.9 0.8 10.0 2.7 1.2 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding RBD-FIP PF09457.5 EXF75409.1 - 8.7 6.2 6.0 6.4 6.6 2.7 1.9 2 0 0 2 2 2 0 FIP domain Peptidase_S24 PF00717.18 EXF75410.1 - 6.4e-08 32.1 0.1 9.3e-08 31.6 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.4 EXF75410.1 - 4.8e-06 26.1 0.0 9.5e-05 21.9 0.0 2.3 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 Arm PF00514.18 EXF75411.1 - 2.1e-70 230.3 33.3 9e-13 47.5 0.1 11.2 11 1 0 11 11 11 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EXF75411.1 - 2.2e-23 82.3 15.4 3.7e-06 27.1 0.2 7.9 2 2 3 6 6 6 6 HEAT repeats HEAT PF02985.17 EXF75411.1 - 9.4e-19 65.7 16.4 0.047 13.7 0.1 9.7 11 0 0 11 11 10 5 HEAT repeat HEAT_EZ PF13513.1 EXF75411.1 - 1.1e-15 57.5 11.6 0.0066 16.9 0.2 8.4 5 1 4 9 9 9 5 HEAT-like repeat Adaptin_N PF01602.15 EXF75411.1 - 1.6e-10 39.9 9.0 2.3e-06 26.2 0.1 3.0 1 1 2 3 3 3 2 Adaptin N terminal region Arm_2 PF04826.8 EXF75411.1 - 5.9e-09 35.4 11.9 0.00088 18.4 0.1 3.4 3 1 1 4 4 4 3 Armadillo-like V-ATPase_H_N PF03224.9 EXF75411.1 - 1.4e-08 34.2 2.0 0.00017 20.7 0.7 3.2 2 1 1 3 3 3 2 V-ATPase subunit H KAP PF05804.7 EXF75411.1 - 2.1e-07 29.3 0.5 4.7e-07 28.1 0.3 1.6 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) DUF2454 PF10521.4 EXF75411.1 - 0.00059 18.9 0.6 0.0062 15.5 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2454) HEAT_PBS PF03130.11 EXF75411.1 - 0.0066 16.8 5.6 37 5.1 0.1 6.9 6 1 0 6 6 6 0 PBS lyase HEAT-like repeat Vac14_Fab1_bd PF12755.2 EXF75411.1 - 0.014 15.7 0.1 0.88 9.9 0.0 3.3 2 1 2 4 4 4 0 Vacuolar 14 Fab1-binding region RIX1 PF08167.7 EXF75411.1 - 0.053 13.1 2.0 0.21 11.2 0.3 2.7 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis Tom37 PF10568.4 EXF75411.1 - 0.25 11.6 1.2 25 5.2 0.0 4.1 4 0 0 4 4 4 0 Outer mitochondrial membrane transport complex protein CBS PF00571.23 EXF75412.1 - 1.7e-31 107.7 6.7 2.2e-13 49.7 0.2 4.4 4 0 0 4 4 4 4 CBS domain RhoGAP PF00620.22 EXF75413.1 - 2.3e-06 27.2 0.0 4.5e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 RhoGAP domain Rep_fac-A_3 PF08661.6 EXF75414.1 - 2.9e-21 75.3 0.0 3.2e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 bZIP_1 PF00170.16 EXF75415.1 - 3.8e-11 42.7 2.1 6.1e-11 42.1 1.4 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EXF75415.1 - 7.1e-07 28.9 2.4 1.4e-06 28.0 1.7 1.6 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EXF75415.1 - 0.0013 18.9 3.2 0.0027 17.9 2.2 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor OmpH PF03938.9 EXF75415.1 - 0.049 13.5 1.5 0.079 12.8 1.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Phlebovirus_NSM PF07246.6 EXF75415.1 - 0.12 11.5 1.4 0.18 10.9 1.0 1.1 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M Mnd1 PF03962.10 EXF75415.1 - 0.2 11.2 4.3 0.3 10.7 3.0 1.2 1 0 0 1 1 1 0 Mnd1 family Ribosomal_L4 PF00573.17 EXF75416.1 - 3.1e-47 160.4 0.0 4e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family PBP PF01161.15 EXF75417.1 - 6.6e-10 39.0 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Paramyxo_C PF01692.13 EXF75418.1 - 0.34 10.4 10.3 0.33 10.5 6.6 1.3 1 1 0 1 1 1 0 Paramyxovirus non-structural protein c Herpes_capsid PF06112.6 EXF75418.1 - 2.4 8.2 13.9 3.4 7.6 9.6 1.3 1 1 0 1 1 1 0 Gammaherpesvirus capsid protein SpoIIIAH PF12685.2 EXF75418.1 - 6.2 6.2 9.9 6.8 6.1 6.9 1.0 1 0 0 1 1 1 0 SpoIIIAH-like protein CobD_Cbib PF03186.8 EXF75419.1 - 0.062 12.3 2.1 0.086 11.8 1.4 1.3 1 1 0 1 1 1 0 CobD/Cbib protein Herpes_TAF50 PF03326.8 EXF75419.1 - 0.11 11.4 1.5 0.11 11.4 1.1 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) DUF2946 PF11162.3 EXF75419.1 - 0.27 11.4 2.5 0.31 11.2 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Alpha_GJ PF03229.8 EXF75419.1 - 0.37 11.1 9.8 0.48 10.7 6.8 1.2 1 0 0 1 1 1 0 Alphavirus glycoprotein J Sporozoite_P67 PF05642.6 EXF75419.1 - 0.42 8.4 5.0 0.44 8.3 3.5 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Herpes_US9 PF06072.6 EXF75421.1 - 0.0065 16.2 4.1 0.012 15.4 2.8 1.4 1 0 0 1 1 1 1 Alphaherpesvirus tegument protein US9 PAN_4 PF14295.1 EXF75421.1 - 0.015 15.0 1.4 0.032 13.9 0.9 1.6 1 0 0 1 1 1 0 PAN domain Glyco_transf_22 PF03901.12 EXF75422.1 - 2.3e-59 201.5 23.0 2.8e-59 201.1 15.9 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PMT_2 PF13231.1 EXF75422.1 - 0.0028 17.5 7.1 0.0028 17.5 4.9 2.3 2 0 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Methyltransf_23 PF13489.1 EXF75423.1 - 8.9e-19 67.7 0.0 1.7e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF75423.1 - 1.6e-11 44.7 0.0 5.5e-11 43.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF75423.1 - 1.8e-11 43.8 0.0 6e-11 42.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF75423.1 - 3.9e-07 30.4 0.0 1.6e-06 28.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF75423.1 - 1.1e-05 25.7 0.0 0.00012 22.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF75423.1 - 1.7e-05 25.1 0.0 4.2e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF75423.1 - 0.0024 17.9 0.0 0.0059 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EXF75423.1 - 0.0049 16.8 0.0 0.014 15.3 0.0 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EXF75423.1 - 0.011 14.8 0.0 0.036 13.1 0.0 1.8 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EXF75423.1 - 0.014 14.9 0.0 0.058 12.9 0.0 2.0 2 1 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EXF75423.1 - 0.014 14.8 0.0 0.047 13.0 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 EXF75423.1 - 0.018 14.1 0.0 0.039 13.0 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.13 EXF75423.1 - 0.15 11.2 0.0 0.28 10.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Cupin_5 PF06172.6 EXF75424.1 - 5.5e-19 68.4 0.0 1.7e-18 66.8 0.0 1.7 1 1 0 1 1 1 1 Cupin superfamily (DUF985) TORC_M PF12885.2 EXF75424.1 - 0.11 12.3 0.3 0.11 12.3 0.2 1.7 2 0 0 2 2 2 0 Transducer of regulated CREB activity middle domain FAP PF07174.6 EXF75424.1 - 1.1 8.4 7.8 2 7.6 5.4 1.4 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Peptidase_M48 PF01435.13 EXF75425.1 - 1.2e-40 139.5 0.0 1.5e-40 139.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Cyt-b5 PF00173.23 EXF75426.1 - 1.3e-20 72.9 0.1 1.4e-20 72.8 0.1 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain BRX PF08381.6 EXF75426.1 - 0.0068 15.4 0.6 0.027 13.5 0.4 1.9 1 1 0 1 1 1 1 Transcription factor regulating root and shoot growth via Pin3 V-ATPase_H_C PF11698.3 EXF75426.1 - 0.047 13.6 0.0 0.076 12.9 0.0 1.4 1 1 0 1 1 1 0 V-ATPase subunit H Kinesin PF00225.18 EXF75427.1 - 5.7e-106 354.0 0.4 1.8e-105 352.3 0.0 1.8 2 0 0 2 2 2 1 Kinesin motor domain DUF3694 PF12473.3 EXF75427.1 - 5.5e-45 152.4 0.0 1.3e-44 151.2 0.0 1.7 1 0 0 1 1 1 1 Kinesin protein KIF1B PF12423.3 EXF75427.1 - 5e-05 23.2 0.5 5e-05 23.2 0.4 2.9 3 0 0 3 3 3 1 Kinesin protein 1B FHA PF00498.21 EXF75427.1 - 0.00011 22.2 0.0 0.00093 19.2 0.0 2.6 3 0 0 3 3 3 1 FHA domain PH PF00169.24 EXF75427.1 - 0.0034 17.5 0.0 0.034 14.3 0.0 2.5 2 0 0 2 2 2 1 PH domain DUF87 PF01935.12 EXF75427.1 - 7.7 6.2 9.4 37 4.0 2.7 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 Uds1 PF15456.1 EXF75428.1 - 3.7e-34 117.3 5.7 3.7e-34 117.3 4.0 2.1 2 0 0 2 2 2 1 Up-regulated During Septation TBPIP PF07106.8 EXF75428.1 - 2.5 7.6 5.8 0.79 9.2 0.8 2.3 2 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GATA PF00320.22 EXF75429.1 - 7.1e-13 47.6 1.4 2.2e-12 46.0 1.0 1.9 1 0 0 1 1 1 1 GATA zinc finger CHZ PF09649.5 EXF75429.1 - 0.11 11.7 0.1 0.22 10.7 0.1 1.4 1 0 0 1 1 1 0 Histone chaperone domain CHZ Bys1 PF04681.7 EXF75430.1 - 9.5e-09 35.1 0.2 1.1e-08 34.9 0.2 1.0 1 0 0 1 1 1 1 Blastomyces yeast-phase-specific protein HET PF06985.6 EXF75432.1 - 1.7e-24 86.5 0.0 3.7e-24 85.4 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ZZ PF00569.12 EXF75432.1 - 5 6.7 8.7 33 4.1 6.0 2.3 1 1 0 1 1 1 0 Zinc finger, ZZ type RasGAP PF00616.14 EXF75433.1 - 2.3e-55 187.3 0.2 1.9e-54 184.3 0.0 2.2 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EXF75433.1 - 1.8e-29 102.2 6.5 1.8e-29 102.2 4.5 2.1 2 0 0 2 2 2 1 RasGAP C-terminus DUF972 PF06156.8 EXF75433.1 - 1.5 9.1 10.3 4.4 7.6 1.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF972) CorA PF01544.13 EXF75434.1 - 1.3e-11 44.1 0.1 3.8e-11 42.5 0.0 1.7 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein Pox_Ag35 PF03286.9 EXF75434.1 - 0.053 13.0 0.2 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DivIVA PF05103.8 EXF75434.1 - 0.13 12.3 0.8 14 5.7 0.1 2.7 3 0 0 3 3 3 0 DivIVA protein Cep57_CLD_2 PF14197.1 EXF75434.1 - 3.8 7.5 6.1 1 9.3 0.8 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 ASF1_hist_chap PF04729.8 EXF75435.1 - 1e-66 223.3 0.0 1.4e-66 222.8 0.0 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Suf PF05843.9 EXF75436.1 - 1.5e-69 234.8 6.7 1.5e-69 234.8 0.0 3.3 4 1 0 4 4 4 1 Suppressor of forked protein (Suf) TPR_16 PF13432.1 EXF75436.1 - 1.5e-07 31.8 0.4 5.5e-05 23.7 1.4 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EXF75436.1 - 8.5e-06 25.9 3.9 0.064 13.9 3.5 4.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EXF75436.1 - 6.1e-05 23.2 0.0 0.003 17.8 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EXF75436.1 - 0.005 16.9 0.1 1.1 9.6 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat HrpJ PF07201.6 EXF75436.1 - 1.2 9.1 9.2 1.3 8.9 0.3 3.6 4 0 0 4 4 4 0 HrpJ-like domain Piwi PF02171.12 EXF75437.1 - 4.1e-76 255.8 0.0 6.1e-76 255.2 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EXF75437.1 - 1.7e-13 49.7 0.3 5.5e-13 48.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EXF75437.1 - 2.5e-12 46.2 0.1 5.1e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 PAZ domain NTP_transferase PF00483.18 EXF75438.1 - 6.5e-05 22.3 0.0 0.0001 21.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotidyl transferase APH PF01636.18 EXF75438.1 - 0.0034 17.1 0.0 0.0075 16.0 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family NTP_transf_3 PF12804.2 EXF75438.1 - 0.0049 16.9 0.0 0.0096 16.0 0.0 1.5 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hydrolase_3 PF08282.7 EXF75438.1 - 0.052 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Nuc_sug_transp PF04142.10 EXF75439.1 - 1.9e-25 89.4 15.9 5.5e-25 87.8 11.0 1.7 1 1 0 1 1 1 1 Nucleotide-sugar transporter EmrE PF13536.1 EXF75439.1 - 0.0039 17.3 1.0 0.0039 17.3 0.7 3.2 3 0 0 3 3 3 1 Multidrug resistance efflux transporter Glyco_hydro_32N PF00251.15 EXF75440.1 - 1.2e-59 202.1 4.8 2.1e-59 201.4 3.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EXF75440.1 - 0.00019 21.7 0.1 0.0023 18.2 0.0 2.6 2 1 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal zf-C2H2 PF00096.21 EXF75442.1 - 1.8e-11 43.6 20.8 1e-05 25.5 1.4 3.6 3 1 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF75442.1 - 5.5e-08 32.6 14.9 0.0063 16.7 1.2 3.5 3 0 0 3 3 3 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EXF75442.1 - 3.8e-07 30.0 9.3 0.0099 16.1 0.2 4.5 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EXF75442.1 - 1.2e-05 25.3 3.4 0.044 13.9 0.8 3.2 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EXF75442.1 - 1.1 9.2 8.4 11 6.0 0.3 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger DUF3505 PF12013.3 EXF75442.1 - 1.8 8.8 5.0 28 4.9 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3505) zf-BED PF02892.10 EXF75442.1 - 4 7.2 8.1 18 5.1 0.2 2.7 2 1 0 2 2 2 0 BED zinc finger Sugar_tr PF00083.19 EXF75443.1 - 4.9e-42 144.0 22.4 1.5e-41 142.4 15.5 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF75443.1 - 3.1e-14 52.4 29.9 6.4e-14 51.4 20.3 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Lgl_C PF08596.5 EXF75444.1 - 3.5e-111 371.4 0.0 5.6e-111 370.7 0.0 1.3 1 0 0 1 1 1 1 Lethal giant larvae(Lgl) like, C-terminal WD40 PF00400.27 EXF75444.1 - 0.00015 21.5 4.0 0.044 13.6 0.0 4.4 5 0 0 5 5 5 1 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EXF75444.1 - 0.047 13.2 0.1 5.8 6.4 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Glyco_hydro_108 PF05838.7 EXF75447.1 - 0.021 14.9 0.0 0.1 12.7 0.0 1.9 2 0 0 2 2 2 0 Glycosyl hydrolase 108 Abhydrolase_6 PF12697.2 EXF75449.1 - 3.3e-17 63.1 0.5 4.3e-17 62.7 0.3 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF75449.1 - 1.5e-09 37.7 0.0 2.1e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF75449.1 - 1.4e-05 24.7 0.0 0.00014 21.5 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold FAD_binding_3 PF01494.14 EXF75452.1 - 1.8e-83 280.5 0.0 2.3e-83 280.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EXF75452.1 - 1.5e-43 148.3 0.0 3.1e-43 147.3 0.0 1.6 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain DAO PF01266.19 EXF75452.1 - 2.4e-06 26.7 0.0 9.2e-05 21.5 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF75452.1 - 8.3e-05 22.5 0.1 0.00099 19.0 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF75452.1 - 0.00016 20.6 0.2 0.00024 20.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EXF75452.1 - 0.00016 20.2 0.0 0.00025 19.6 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EXF75452.1 - 0.0016 17.6 0.0 0.0048 16.0 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 EXF75452.1 - 0.0017 18.7 0.0 0.0038 17.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF75452.1 - 0.0025 16.7 0.2 0.0068 15.3 0.0 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EXF75452.1 - 0.0026 16.7 0.0 0.0042 16.0 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EXF75452.1 - 0.005 16.8 0.1 0.014 15.3 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EXF75452.1 - 0.02 14.0 0.1 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EXF75452.1 - 0.023 14.7 0.1 0.069 13.1 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.1 EXF75452.1 - 0.13 12.5 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain SE PF08491.5 EXF75452.1 - 0.2 10.4 0.0 2.5 6.8 0.0 2.0 2 0 0 2 2 2 0 Squalene epoxidase Clp1 PF06807.9 EXF75453.1 - 6.7e-07 29.2 0.0 0.0011 18.7 0.0 2.3 2 0 0 2 2 2 2 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EXF75453.1 - 0.0046 16.6 0.0 0.013 15.2 0.0 1.7 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B RNA_polI_A34 PF08208.6 EXF75454.1 - 3.2e-30 105.3 7.2 3.2e-30 105.3 5.0 6.4 4 2 1 5 5 5 1 DNA-directed RNA polymerase I subunit RPA34.5 PAP2 PF01569.16 EXF75457.1 - 1.1e-13 50.9 4.0 1.1e-13 50.9 2.8 2.2 1 1 1 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EXF75457.1 - 4.6e-06 26.2 4.8 1.2e-05 24.9 3.3 1.7 1 1 0 1 1 1 1 PAP2 superfamily Peptidase_M3 PF01432.15 EXF75459.1 - 3.5e-106 355.9 0.0 7e-55 186.8 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M3 HNH PF01844.18 EXF75461.1 - 5.8e-05 22.8 2.0 0.00013 21.7 1.4 1.6 1 0 0 1 1 1 1 HNH endonuclease HAD_2 PF13419.1 EXF75462.1 - 1.7e-23 83.7 0.0 2.4e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EXF75462.1 - 0.00055 19.5 0.0 0.00096 18.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like D5_N PF08706.6 EXF75462.1 - 0.002 18.2 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 D5 N terminal like AAA_5 PF07728.9 EXF75462.1 - 0.038 13.7 0.0 0.18 11.5 0.1 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Glyco_trans_1_2 PF13524.1 EXF75462.1 - 0.076 13.2 0.0 0.2 11.9 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 UCH PF00443.24 EXF75463.1 - 7.5e-62 208.8 1.5 8.2e-62 208.7 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EXF75463.1 - 1.5e-30 106.6 0.5 4.9e-23 81.9 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EXF75463.1 - 0.08 12.2 2.3 1.2 8.3 0.6 3.0 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase VIT1 PF01988.14 EXF75463.1 - 3 7.2 7.3 6.2 6.2 5.1 1.4 1 0 0 1 1 1 0 VIT family Glyco_transf_22 PF03901.12 EXF75464.1 - 2.1e-41 142.2 11.6 2.7e-41 141.9 8.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family PP2C PF00481.16 EXF75465.1 - 1.7e-58 198.0 0.0 5e-58 196.4 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_4 PF12799.2 EXF75465.1 - 6.6e-51 169.2 68.8 6.7e-08 31.9 1.6 13.0 6 2 8 14 14 14 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EXF75465.1 - 1.7e-37 126.9 59.1 2.4e-09 36.7 1.1 9.9 5 3 5 11 11 11 10 Leucine rich repeat Guanylate_cyc PF00211.15 EXF75465.1 - 9e-32 109.9 0.1 2.2e-31 108.6 0.0 1.6 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain LRR_1 PF00560.28 EXF75465.1 - 1.1e-21 73.4 60.8 0.24 11.5 0.2 20.0 19 1 0 19 19 19 8 Leucine Rich Repeat Ad_cyc_g-alpha PF08509.6 EXF75465.1 - 4.4e-15 54.7 0.7 4.4e-15 54.7 0.5 2.5 2 0 0 2 2 2 1 Adenylate cyclase G-alpha binding domain LRR_7 PF13504.1 EXF75465.1 - 2.4e-13 47.9 48.5 0.98 9.9 0.1 18.2 20 0 0 20 20 20 3 Leucine rich repeat RA PF00788.18 EXF75465.1 - 3.7e-08 33.7 0.0 2.2e-07 31.2 0.0 2.4 3 0 0 3 3 3 1 Ras association (RalGDS/AF-6) domain Aldo_ket_red PF00248.16 EXF75466.1 - 2e-72 243.3 0.0 2.3e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Alpha-amylase PF00128.19 EXF75467.1 - 7.3e-99 331.1 0.8 1.1e-98 330.5 0.5 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.13 EXF75467.1 - 0.011 15.9 0.0 0.032 14.3 0.0 1.9 1 0 0 1 1 1 0 Alpha amylase, C-terminal all-beta domain Fungal_trans PF04082.13 EXF75468.1 - 5.4e-14 51.6 0.0 9e-14 50.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF75468.1 - 3.6e-08 33.1 5.6 5.9e-08 32.4 3.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EXF75469.1 - 9.6e-22 77.1 22.1 1.3e-21 76.7 15.3 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TauD PF02668.11 EXF75470.1 - 3.1e-50 171.2 0.0 4.2e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family RTC4 PF14474.1 EXF75471.1 - 3.5e-30 104.4 0.0 7.5e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 RTC4-like domain Dynamitin PF04912.9 EXF75472.1 - 7.8e-36 123.6 2.0 8.5e-35 120.2 1.4 2.4 1 1 0 1 1 1 1 Dynamitin FH2 PF02181.18 EXF75472.1 - 4.8e-05 22.4 2.9 0.51 9.1 0.0 3.1 3 0 0 3 3 3 2 Formin Homology 2 Domain RPN7 PF10602.4 EXF75472.1 - 0.012 14.9 2.1 0.015 14.6 0.4 1.9 2 0 0 2 2 2 0 26S proteasome subunit RPN7 IFT57 PF10498.4 EXF75472.1 - 0.013 14.2 3.6 0.48 9.1 0.0 3.0 3 0 0 3 3 3 0 Intra-flagellar transport protein 57 Phage_GP20 PF06810.6 EXF75472.1 - 0.018 14.4 1.6 0.018 14.4 1.1 2.9 3 0 0 3 3 3 0 Phage minor structural protein GP20 DUF706 PF05153.10 EXF75472.1 - 0.053 12.8 0.1 0.087 12.1 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF706) BLOC1_2 PF10046.4 EXF75472.1 - 0.077 13.1 9.1 3 8.0 1.3 3.9 3 2 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Allexi_40kDa PF05549.6 EXF75472.1 - 0.097 11.9 2.1 1.5 8.0 0.2 2.6 3 0 0 3 3 3 0 Allexivirus 40kDa protein ISG65-75 PF11727.3 EXF75472.1 - 0.1 11.6 4.5 7.2 5.5 0.6 3.0 3 0 0 3 3 3 0 Invariant surface glycoprotein Laminin_II PF06009.7 EXF75472.1 - 0.12 12.1 7.4 1.3 8.7 0.1 3.9 3 1 1 4 4 4 0 Laminin Domain II ATP-synt_E PF05680.7 EXF75472.1 - 0.13 12.2 3.4 0.15 12.0 0.3 2.3 2 0 0 2 2 2 0 ATP synthase E chain AAA_13 PF13166.1 EXF75472.1 - 0.15 10.4 2.4 0.28 9.6 0.1 2.2 3 0 0 3 3 3 0 AAA domain RmuC PF02646.11 EXF75472.1 - 0.2 10.4 4.1 0.51 9.1 0.1 2.6 3 0 0 3 3 3 0 RmuC family Spore_III_AB PF09548.5 EXF75472.1 - 0.21 11.3 5.5 0.32 10.7 0.1 3.2 3 1 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) CENP-F_leu_zip PF10473.4 EXF75472.1 - 0.27 11.0 10.2 1 9.1 0.8 3.3 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GrpE PF01025.14 EXF75472.1 - 0.31 10.5 3.5 1.1 8.7 0.6 2.8 3 0 0 3 3 3 0 GrpE Snf7 PF03357.16 EXF75472.1 - 0.66 9.3 8.1 0.5 9.7 0.1 3.0 3 0 0 3 3 3 0 Snf7 Baculo_PEP_C PF04513.7 EXF75472.1 - 1.8 8.3 5.7 7.9 6.2 0.9 3.0 2 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus COG2 PF06148.6 EXF75472.1 - 3 7.7 5.6 4.8 7.0 0.1 3.2 3 1 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 TBPIP PF07106.8 EXF75472.1 - 3.1 7.3 7.8 0.83 9.1 1.0 2.7 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) IncA PF04156.9 EXF75472.1 - 4.1 6.9 8.7 7.1 6.1 0.8 2.6 3 0 0 3 3 3 0 IncA protein Mnd1 PF03962.10 EXF75472.1 - 4.4 6.9 12.0 1.3 8.6 1.6 3.0 2 1 0 2 2 2 0 Mnd1 family DUF4337 PF14235.1 EXF75472.1 - 4.5 7.0 6.8 6.8 6.5 1.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) Ribosomal_S28e PF01200.13 EXF75473.1 - 4.6e-34 115.9 2.5 4.9e-34 115.8 1.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e ThiS PF02597.15 EXF75474.1 - 7.4e-10 39.1 0.0 1e-09 38.7 0.0 1.2 1 0 0 1 1 1 1 ThiS family PSI PF01437.20 EXF75475.1 - 6.9e-05 22.9 9.7 6.9e-05 22.9 6.7 1.9 2 0 0 2 2 2 1 Plexin repeat HemY_N PF07219.8 EXF75475.1 - 0.11 11.9 2.9 0.18 11.3 2.0 1.2 1 0 0 1 1 1 0 HemY protein N-terminus Sugar_tr PF00083.19 EXF75476.1 - 2.3e-82 276.9 20.6 2.6e-82 276.7 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF75476.1 - 3.4e-26 91.8 35.0 7.7e-21 74.1 5.8 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EXF75476.1 - 5.6e-05 21.7 3.5 5.6e-05 21.7 2.5 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein TRI12 PF06609.8 EXF75476.1 - 0.0004 18.7 2.4 0.003 15.8 0.5 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) IBR PF01485.16 EXF75477.1 - 2.6e-06 27.1 33.5 1.8e-05 24.5 8.7 3.3 3 1 0 3 3 3 2 IBR domain RNA_pol_Rpb1_5 PF04998.12 EXF75477.1 - 0.6 9.3 2.0 1.2 8.3 1.0 1.5 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Mo-nitro_C PF06967.6 EXF75477.1 - 1.3 9.2 4.6 1.1 9.4 0.6 2.5 3 0 0 3 3 3 0 Mo-dependent nitrogenase C-terminus FAA_hydrolase PF01557.13 EXF75478.1 - 4.6e-59 199.5 0.0 5.8e-59 199.1 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family SNF2_N PF00176.18 EXF75480.1 - 2.3e-58 197.3 0.0 3.8e-58 196.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EXF75480.1 - 1.4e-14 53.7 0.1 4.4e-14 52.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain UBA PF00627.26 EXF75480.1 - 0.001 18.8 0.2 0.0036 17.0 0.1 2.0 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.11 EXF75480.1 - 0.04 13.4 0.1 0.094 12.2 0.1 1.7 1 0 0 1 1 1 0 CUE domain HBS1_N PF08938.5 EXF75480.1 - 0.22 11.6 0.1 0.22 11.6 0.1 3.3 3 0 0 3 3 3 0 HBS1 N-terminus VMA21 PF09446.5 EXF75481.1 - 1.5e-16 60.0 7.9 2e-16 59.6 5.4 1.2 1 0 0 1 1 1 1 VMA21-like domain DUF2406 PF10295.4 EXF75482.1 - 2.3e-21 76.0 0.9 2.3e-21 76.0 0.7 2.5 2 0 0 2 2 2 1 Uncharacterised protein (DUF2406) CorA PF01544.13 EXF75484.1 - 7.9e-42 143.2 1.4 9.8e-41 139.6 1.0 2.1 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Ribosomal_L29e PF01779.12 EXF75484.1 - 0.71 9.7 8.5 4.3 7.2 0.0 2.6 2 0 0 2 2 2 0 Ribosomal L29e protein family CBF PF03914.12 EXF75485.1 - 3.3e-45 153.4 0.8 7.7e-45 152.2 0.1 2.0 2 0 0 2 2 2 1 CBF/Mak21 family Utp12 PF04003.7 EXF75485.1 - 0.08 12.8 0.2 0.22 11.4 0.2 1.7 1 0 0 1 1 1 0 Dip2/Utp12 Family DUF1655 PF07868.6 EXF75485.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1655) Mt_ATP-synt_B PF05405.9 EXF75486.1 - 1.8e-53 180.3 2.7 2.3e-53 180.0 1.9 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) tRNA_anti-codon PF01336.20 EXF75486.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain MSC PF09402.5 EXF75487.1 - 8.2e-99 330.4 0.0 1.1e-98 330.0 0.0 1.1 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain HeH PF12949.2 EXF75487.1 - 4.2e-18 64.5 0.1 8.2e-18 63.6 0.1 1.5 1 0 0 1 1 1 1 HeH/LEM domain Thymopoietin PF08198.6 EXF75487.1 - 0.039 13.4 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 Thymopoietin protein DUF3637 PF12337.3 EXF75487.1 - 0.088 12.7 0.0 0.27 11.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3637) DUF3350 PF11830.3 EXF75487.1 - 0.34 10.9 4.6 1.3 9.0 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3350) FAD_binding_3 PF01494.14 EXF75488.1 - 2.2e-24 86.2 0.0 8.6e-23 80.9 0.0 2.2 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF75488.1 - 1.3e-05 24.3 0.0 0.028 13.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.5 EXF75488.1 - 0.00045 19.1 0.0 0.00073 18.4 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase Lycopene_cycl PF05834.7 EXF75488.1 - 0.00055 18.9 0.6 0.003 16.5 0.0 2.4 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EXF75488.1 - 0.0063 16.3 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EXF75488.1 - 0.015 15.2 0.0 0.032 14.1 0.0 1.7 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF75488.1 - 0.034 13.0 0.1 0.11 11.4 0.0 1.8 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EXF75488.1 - 0.089 12.8 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain E1-N PF14463.1 EXF75488.1 - 0.096 12.2 0.2 0.32 10.5 0.1 1.8 2 0 0 2 2 2 0 E1 N-terminal domain Trp_halogenase PF04820.9 EXF75488.1 - 0.1 11.1 0.0 1.4 7.4 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase Complex1_49kDa PF00346.14 EXF75489.1 - 1.4e-130 434.2 0.0 1.8e-130 433.8 0.0 1.1 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit SNase PF00565.12 EXF75490.1 - 1.8e-21 76.3 0.1 2.7e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue Pkinase PF00069.20 EXF75491.1 - 5.1e-57 192.9 0.0 7.2e-57 192.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF75491.1 - 5.2e-41 140.4 0.0 8.2e-41 139.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF75491.1 - 5.8e-05 22.1 0.0 0.00024 20.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EXF75491.1 - 0.017 14.8 0.0 0.076 12.7 0.0 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EXF75491.1 - 0.27 10.2 0.0 0.63 9.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Telomere_reg-2 PF10193.4 EXF75492.1 - 1.6e-39 134.7 0.0 8.1e-39 132.4 0.0 2.3 2 0 0 2 2 2 1 Telomere length regulation protein ThiF PF00899.16 EXF75493.1 - 1.4e-38 131.7 0.9 3.3e-38 130.5 0.2 1.8 2 0 0 2 2 2 1 ThiF family E2_bind PF08825.5 EXF75493.1 - 5.5e-29 99.7 0.1 1.2e-28 98.7 0.1 1.6 1 0 0 1 1 1 1 E2 binding domain UBACT PF02134.16 EXF75493.1 - 7e-25 86.3 2.4 9.3e-25 86.0 0.7 1.9 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EXF75493.1 - 4.1e-15 54.8 2.3 4.1e-15 54.8 1.6 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.15 EXF75493.1 - 5.3e-05 23.3 0.1 0.00011 22.3 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase UAE_UbL PF14732.1 EXF75493.1 - 0.0022 18.0 0.1 0.034 14.2 0.0 2.5 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 EXF75493.1 - 0.034 14.3 0.1 0.078 13.2 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding RNA_pol_A_bac PF01000.21 EXF75494.1 - 1.2e-28 99.4 0.0 2.5e-28 98.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EXF75494.1 - 5.4e-14 51.0 0.0 8.8e-14 50.3 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain BTB_2 PF02214.17 EXF75495.1 - 0.00017 21.7 0.2 0.00041 20.4 0.1 1.7 2 0 0 2 2 2 1 BTB/POZ domain OTT_1508_deam PF14441.1 EXF75496.1 - 4e-11 42.9 0.5 2.9e-10 40.1 0.2 2.4 1 1 1 2 2 2 1 OTT_1508-like deaminase DUF605 PF04652.11 EXF75496.1 - 5.2 6.3 16.1 8 5.7 11.2 1.2 1 0 0 1 1 1 0 Vta1 like PTP_N PF12453.3 EXF75497.1 - 0.21 11.2 1.7 0.48 10.0 1.2 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase N terminal AAA PF00004.24 EXF75498.1 - 1.7e-54 183.5 0.0 1.9e-43 147.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.6 EXF75498.1 - 6.2e-28 96.6 0.1 1.6e-27 95.3 0.1 1.8 1 0 0 1 1 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.1 EXF75498.1 - 3.1e-13 50.1 2.4 3e-07 30.5 0.1 3.9 2 1 1 3 3 3 2 AAA ATPase domain NACHT PF05729.7 EXF75498.1 - 4.2e-08 33.0 0.4 7.7e-05 22.4 0.0 3.4 3 0 0 3 3 3 1 NACHT domain AAA_17 PF13207.1 EXF75498.1 - 2.8e-07 31.3 0.3 0.027 15.2 0.1 3.0 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EXF75498.1 - 3.8e-06 27.2 0.1 0.0026 18.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EXF75498.1 - 6.8e-06 26.0 0.0 0.063 13.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EXF75498.1 - 7.7e-06 25.1 0.0 0.013 14.5 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EXF75498.1 - 1.1e-05 24.3 0.0 0.018 13.7 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_22 PF13401.1 EXF75498.1 - 1.4e-05 25.2 0.8 0.31 11.1 0.1 3.7 2 2 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EXF75498.1 - 2.8e-05 24.0 0.0 0.23 11.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EXF75498.1 - 3.4e-05 23.7 0.0 0.4 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EXF75498.1 - 4.3e-05 22.7 0.9 0.37 9.8 0.0 3.3 3 0 0 3 3 3 2 Zeta toxin AAA_19 PF13245.1 EXF75498.1 - 7.5e-05 22.4 0.0 0.33 10.7 0.0 3.2 2 0 0 2 2 2 2 Part of AAA domain AAA_5 PF07728.9 EXF75498.1 - 0.00011 21.9 0.1 0.49 10.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EXF75498.1 - 0.00019 20.9 0.3 0.37 10.1 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activ_2 PF14532.1 EXF75498.1 - 0.00023 21.2 0.0 0.079 13.0 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain SKI PF01202.17 EXF75498.1 - 0.00053 19.8 0.1 0.38 10.6 0.0 2.5 2 0 0 2 2 2 1 Shikimate kinase AAA_25 PF13481.1 EXF75498.1 - 0.001 18.5 4.3 1.7 8.0 0.2 4.3 2 2 2 4 4 4 1 AAA domain UPF0079 PF02367.12 EXF75498.1 - 0.0015 18.1 0.1 0.033 13.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 RNA_helicase PF00910.17 EXF75498.1 - 0.0018 18.4 0.0 2.9 8.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_28 PF13521.1 EXF75498.1 - 0.0029 17.5 0.2 0.99 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.1 EXF75498.1 - 0.0032 17.3 0.0 2.1 8.2 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family Mg_chelatase PF01078.16 EXF75498.1 - 0.0049 16.0 0.5 0.67 9.0 0.0 2.7 3 0 0 3 3 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EXF75498.1 - 0.0086 15.5 0.1 0.85 9.0 0.0 3.0 4 0 0 4 4 3 1 Sigma-54 interaction domain Viral_helicase1 PF01443.13 EXF75498.1 - 0.039 13.4 0.0 3.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase KaiC PF06745.8 EXF75498.1 - 0.043 12.9 0.0 11 5.1 0.0 2.4 2 0 0 2 2 2 0 KaiC ABC_tran PF00005.22 EXF75498.1 - 0.043 14.1 0.0 22 5.3 0.0 2.9 2 0 0 2 2 2 0 ABC transporter Arch_ATPase PF01637.13 EXF75498.1 - 0.052 13.2 0.0 6.5 6.3 0.0 2.9 2 1 1 3 3 3 0 Archaeal ATPase DUF2075 PF09848.4 EXF75498.1 - 0.059 12.3 0.0 6.9 5.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_29 PF13555.1 EXF75498.1 - 0.067 12.7 0.0 0.81 9.2 0.1 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_3 PF07726.6 EXF75498.1 - 0.13 11.8 0.0 6.6 6.3 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 EXF75498.1 - 0.15 11.8 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DUF815 PF05673.8 EXF75498.1 - 0.19 10.6 0.0 2.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NB-ARC PF00931.17 EXF75498.1 - 0.22 10.3 0.6 6.5 5.5 0.0 2.5 3 0 0 3 3 2 0 NB-ARC domain MCM PF00493.18 EXF75499.1 - 3.1e-135 450.2 0.0 4.9e-135 449.5 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EXF75499.1 - 1.6e-23 83.5 0.2 5.3e-23 81.8 0.1 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EXF75499.1 - 1.2e-07 31.1 0.0 1.4e-05 24.3 0.0 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EXF75499.1 - 5.2e-06 26.2 0.0 1.7e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase_2 PF13335.1 EXF75499.1 - 0.0075 16.6 1.9 0.017 15.5 0.1 2.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EXF75499.1 - 0.018 14.6 0.0 0.065 12.8 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RecX PF02631.11 EXF75499.1 - 0.043 14.0 1.0 0.29 11.3 0.2 2.4 2 0 0 2 2 2 0 RecX family Sigma54_activat PF00158.21 EXF75499.1 - 0.12 11.8 0.0 1 8.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain Acetyltransf_6 PF13480.1 EXF75499.1 - 0.77 9.7 3.2 0.9 9.4 0.8 2.0 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain DAP3 PF10236.4 EXF75500.1 - 2.2e-90 302.7 0.0 2.9e-90 302.3 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal death-associated protein 3 AAA_14 PF13173.1 EXF75500.1 - 0.17 11.8 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain RRS1 PF04939.7 EXF75501.1 - 3.5e-57 192.4 7.1 4.1e-57 192.2 4.9 1.0 1 0 0 1 1 1 1 Ribosome biogenesis regulatory protein (RRS1) RhoGAP PF00620.22 EXF75502.1 - 4.9e-28 97.6 0.0 9.6e-28 96.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Prenyltrans PF00432.16 EXF75503.1 - 1.7e-54 181.0 11.1 1.9e-11 43.3 0.0 6.1 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EXF75503.1 - 4.2e-35 120.5 0.0 3.2e-13 50.0 0.0 4.0 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EXF75503.1 - 6.4e-10 39.0 0.0 0.00082 19.3 0.0 2.7 2 1 1 3 3 3 2 Prenyltransferase-like zf-C2H2_2 PF12756.2 EXF75504.1 - 0.032 14.3 0.0 0.076 13.1 0.0 1.6 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EXF75504.1 - 0.3 11.5 1.2 1 9.8 0.8 2.0 1 0 0 1 1 1 0 Zinc finger, C2H2 type MutS_V PF00488.16 EXF75505.1 - 1.3e-80 270.2 0.0 1.9e-80 269.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EXF75505.1 - 1.6e-37 129.2 1.8 2.8e-37 128.4 1.2 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EXF75505.1 - 5.6e-28 97.2 0.0 1.2e-27 96.2 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EXF75505.1 - 6.9e-12 45.6 0.0 2.9e-11 43.6 0.0 2.1 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EXF75505.1 - 4.4e-07 29.9 0.0 1.2e-06 28.6 0.0 1.8 1 0 0 1 1 1 1 MutS family domain IV AAA_29 PF13555.1 EXF75505.1 - 0.15 11.5 0.1 0.42 10.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Abhydrolase_3 PF07859.8 EXF75506.1 - 9.4e-43 146.2 0.0 1.2e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EXF75506.1 - 0.00047 18.9 0.1 0.00083 18.1 0.1 1.3 1 1 0 1 1 1 1 Carboxylesterase family COX17 PF05051.8 EXF75507.1 - 1.2e-19 70.0 5.6 1.4e-19 69.8 3.9 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) G-patch PF01585.18 EXF75508.1 - 2.4e-05 24.0 0.0 9.9e-05 22.0 0.0 2.2 1 1 0 1 1 1 1 G-patch domain MIP-T3 PF10243.4 EXF75508.1 - 0.035 12.5 72.9 0.047 12.1 50.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CDC27 PF09507.5 EXF75508.1 - 0.1 11.7 62.4 0.14 11.3 43.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Borrelia_P83 PF05262.6 EXF75508.1 - 1.3 7.2 41.4 2 6.5 28.7 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein TFIIF_alpha PF05793.7 EXF75508.1 - 5.6 5.2 68.9 11 4.2 47.7 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) PITH PF06201.8 EXF75514.1 - 5.7e-40 136.5 0.0 7.7e-40 136.1 0.0 1.2 1 0 0 1 1 1 1 PITH domain Thioredoxin PF00085.15 EXF75514.1 - 2.3e-28 97.9 0.1 3.4e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EXF75514.1 - 1.2e-07 31.6 0.0 1.3e-05 25.2 0.0 2.4 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EXF75514.1 - 5.4e-06 26.5 0.0 1.5e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EXF75514.1 - 0.00061 19.7 0.0 0.0017 18.3 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 EXF75514.1 - 0.0044 16.6 0.0 0.016 14.8 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.1 EXF75514.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.5 EXF75514.1 - 0.11 12.0 0.1 0.31 10.5 0.1 1.8 1 1 0 1 1 1 0 Redoxin DUF3246 PF11596.3 EXF75514.1 - 0.44 9.7 2.7 0.75 9.0 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) PRANC PF09372.5 EXF75516.1 - 0.075 13.0 0.2 4 7.4 0.0 2.6 2 0 0 2 2 2 0 PRANC domain Med11 PF10280.4 EXF75516.1 - 4.3 7.4 6.7 1.4e+02 2.5 4.7 2.8 1 1 0 1 1 1 0 Mediator complex protein DivIC PF04977.10 EXF75517.1 - 0.013 15.0 0.4 0.022 14.2 0.3 1.3 1 0 0 1 1 1 0 Septum formation initiator GAS PF13851.1 EXF75517.1 - 0.055 12.6 0.1 0.086 12.0 0.1 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Vg_Tdu PF07545.9 EXF75517.1 - 0.1 12.0 0.1 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Vestigial/Tondu family ADH_zinc_N PF00107.21 EXF75518.1 - 1.2e-07 31.2 0.0 2.8e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF75518.1 - 0.00013 21.6 0.0 0.00039 20.1 0.0 1.9 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain CorA PF01544.13 EXF75520.1 - 2.9e-15 56.0 4.6 1.2e-11 44.2 0.0 2.9 3 0 0 3 3 3 2 CorA-like Mg2+ transporter protein DUF4231 PF14015.1 EXF75520.1 - 0.024 14.5 0.3 0.065 13.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) FadA PF09403.5 EXF75520.1 - 5.8 6.9 11.4 6.8 6.7 0.0 3.4 4 0 0 4 4 4 0 Adhesion protein FadA RhoGAP PF00620.22 EXF75522.1 - 4.3e-44 149.7 0.2 2.3e-43 147.4 0.1 2.1 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 EXF75522.1 - 2.5e-09 37.2 0.0 5.7e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EXF75522.1 - 1.5e-07 31.6 0.0 1e-06 28.9 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EXF75522.1 - 0.016 15.2 0.1 0.24 11.4 0.0 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Fungal_trans PF04082.13 EXF75523.1 - 1.2e-05 24.3 0.0 2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF75523.1 - 0.00013 21.7 10.8 0.00021 21.1 7.5 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2360 PF10152.4 EXF75523.1 - 0.12 12.6 0.0 0.12 12.6 0.0 3.0 3 0 0 3 3 3 0 Predicted coiled-coil domain-containing protein (DUF2360) Ctr PF04145.10 EXF75524.1 - 4e-11 43.1 0.0 4.7e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Ctr copper transporter family OPT PF03169.10 EXF75525.1 - 6.6e-135 450.9 55.2 7.5e-135 450.7 38.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Nuc-transf PF10127.4 EXF75527.1 - 0.0085 15.4 0.0 0.32 10.2 0.0 2.1 2 0 0 2 2 2 2 Predicted nucleotidyltransferase Fungal_trans PF04082.13 EXF75528.1 - 1e-07 31.1 0.0 2.7e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Meleagrin PF08189.6 EXF75528.1 - 0.068 12.6 0.1 0.17 11.3 0.1 1.6 1 0 0 1 1 1 0 Meleagrin/Cygnin family MFS_1 PF07690.11 EXF75530.1 - 4.1e-28 98.1 60.9 6.3e-20 71.1 22.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EXF75530.1 - 0.00092 18.9 2.3 0.0029 17.3 0.9 2.4 2 0 0 2 2 2 1 MFS_1 like family Sugar_tr PF00083.19 EXF75530.1 - 0.0038 15.8 19.6 0.0038 15.8 13.6 3.7 2 2 2 4 4 4 2 Sugar (and other) transporter AIM24 PF01987.12 EXF75531.1 - 3.3e-48 163.9 0.0 4.5e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 DUF4402 PF14352.1 EXF75531.1 - 0.1 13.0 0.1 0.21 12.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) Kinesin PF00225.18 EXF75532.1 - 6.4e-81 271.6 0.0 9e-81 271.1 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain HHH_3 PF12836.2 EXF75532.1 - 0.0031 17.4 0.1 0.023 14.6 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif p450 PF00067.17 EXF75533.1 - 1.2e-39 136.1 1.1 4.1e-25 88.2 0.1 2.0 2 0 0 2 2 2 2 Cytochrome P450 Methyltrn_RNA_4 PF09936.4 EXF75533.1 - 0.0098 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 SAM-dependent RNA methyltransferase GlutR_dimer PF00745.15 EXF75534.1 - 0.05 13.5 0.3 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 Glutamyl-tRNAGlu reductase, dimerisation domain Iso_dh PF00180.15 EXF75535.1 - 2.2e-119 398.4 0.0 2.7e-119 398.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CN_hydrolase PF00795.17 EXF75536.1 - 1.3e-15 57.2 0.0 1.9e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.11 EXF75537.1 - 1.6e-36 125.7 39.4 4.9e-36 124.1 25.9 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 EXF75537.1 - 0.0027 15.8 1.4 0.0052 14.8 1.0 1.4 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Zn_clus PF00172.13 EXF75538.1 - 3.1e-06 26.9 9.2 3.1e-06 26.9 6.4 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dioxygenase_C PF00775.16 EXF75540.1 - 2e-11 43.4 1.9 1e-10 41.1 1.3 2.0 1 1 0 1 1 1 1 Dioxygenase HET PF06985.6 EXF75541.1 - 8.3e-15 55.1 0.9 1.6e-14 54.2 0.1 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) CDC45 PF02724.9 EXF75541.1 - 0.1 10.5 6.9 0.18 9.8 4.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2722 PF10846.3 EXF75541.1 - 0.39 9.6 1.2 0.67 8.9 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) YL1 PF05764.8 EXF75541.1 - 0.48 9.9 10.0 0.89 9.1 6.9 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Amidase PF01425.16 EXF75542.1 - 3.9e-93 312.6 0.0 9.8e-93 311.3 0.0 1.6 1 1 0 1 1 1 1 Amidase Peptidase_A6 PF01829.11 EXF75542.1 - 0.017 14.1 0.2 0.029 13.4 0.1 1.3 1 0 0 1 1 1 0 Peptidase A6 family Zn_clus PF00172.13 EXF75543.1 - 8.7e-09 35.1 8.7 1.7e-08 34.2 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain TRI12 PF06609.8 EXF75544.1 - 1.8e-81 274.1 17.2 2.2e-81 273.8 11.9 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EXF75544.1 - 3.6e-29 101.6 46.5 1.2e-28 99.8 31.2 2.1 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF75544.1 - 8.1e-09 34.5 11.2 8.1e-09 34.5 7.8 3.5 3 2 0 3 3 3 1 Sugar (and other) transporter ECH PF00378.15 EXF75545.1 - 2.2e-53 180.8 0.1 2.7e-53 180.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH PF00378.15 EXF75546.1 - 1.1e-37 129.4 0.0 1.4e-37 129.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family MaoC_dehydratas PF01575.14 EXF75547.1 - 4.5e-23 80.9 0.0 6.7e-23 80.3 0.0 1.3 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EXF75547.1 - 6.4e-08 32.4 0.1 1.3e-05 24.9 0.0 2.6 2 1 0 2 2 2 2 N-terminal half of MaoC dehydratase DUF1446 PF07287.6 EXF75548.1 - 4.5e-122 407.0 0.1 5.4e-122 406.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) AMP-binding PF00501.23 EXF75549.1 - 9.9e-73 244.8 0.0 1.3e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EXF75549.1 - 2.1e-07 31.7 0.0 4.8e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF4448 PF14610.1 EXF75550.1 - 1.7e-30 105.9 0.0 3e-30 105.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) DUF2029 PF09594.5 EXF75550.1 - 0.015 14.8 3.2 0.017 14.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2029) DUF3149 PF11346.3 EXF75550.1 - 0.076 12.5 0.1 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3149) DUF4181 PF13789.1 EXF75550.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) HAMP PF00672.20 EXF75550.1 - 0.12 12.5 0.4 0.22 11.7 0.3 1.4 1 0 0 1 1 1 0 HAMP domain DUF3384 PF11864.3 EXF75550.1 - 0.15 10.5 0.0 0.19 10.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) GSDH PF07995.6 EXF75552.1 - 1.5e-05 24.2 0.2 0.00025 20.2 0.1 2.5 2 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase SGL PF08450.7 EXF75552.1 - 4.4e-05 22.9 0.7 0.0074 15.6 0.0 2.7 3 0 0 3 3 3 2 SMP-30/Gluconolaconase/LRE-like region PepSY_2 PF13670.1 EXF75552.1 - 0.23 11.3 1.7 0.77 9.6 1.1 1.9 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain DUF2763 PF10961.3 EXF75553.1 - 0.032 14.6 0.1 0.08 13.3 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2763) SAD_SRA PF02182.12 EXF75555.1 - 4.5e-06 26.0 0.0 7.4e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 SAD/SRA domain SurE PF01975.12 EXF75558.1 - 0.38 10.0 7.4 0.52 9.5 5.1 1.3 1 0 0 1 1 1 0 Survival protein SurE Lipase_GDSL PF00657.17 EXF75560.1 - 6.4e-14 52.3 0.1 1e-13 51.6 0.1 1.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EXF75560.1 - 2.2e-11 44.2 0.2 3e-11 43.7 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF4185 PF13810.1 EXF75560.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4185) ASCH PF04266.9 EXF75561.1 - 1.4e-17 63.9 0.1 1.9e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 ASCH domain p450 PF00067.17 EXF75562.1 - 8.6e-48 162.9 0.0 1.2e-47 162.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 EXF75563.1 - 0.0044 16.8 10.5 0.014 15.2 7.3 1.9 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RTA1 PF04479.8 EXF75564.1 - 1.7e-35 122.5 10.2 2.7e-35 121.9 7.0 1.2 1 0 0 1 1 1 1 RTA1 like protein MASE2 PF05230.6 EXF75564.1 - 0.095 12.6 3.8 0.32 10.9 2.6 1.9 1 0 0 1 1 1 0 MASE2 domain Tmemb_55A PF09788.4 EXF75564.1 - 0.13 11.3 1.9 0.28 10.2 1.3 1.5 1 0 0 1 1 1 0 Transmembrane protein 55A DUF2964 PF11177.3 EXF75564.1 - 8.8 6.3 11.7 0.33 10.9 0.3 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2964) AAA_33 PF13671.1 EXF75565.1 - 0.0021 17.9 0.0 0.003 17.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain Fungal_trans PF04082.13 EXF75566.1 - 1.7e-26 92.6 0.1 2.6e-26 92.0 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_1 PF01979.15 EXF75567.1 - 1.3e-40 140.0 0.2 1.6e-40 139.8 0.2 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EXF75567.1 - 6e-19 69.1 0.6 1.6e-17 64.4 0.4 2.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EXF75567.1 - 5.4e-11 42.1 0.0 1.9e-10 40.4 0.0 2.0 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EXF75567.1 - 5.6e-11 42.3 3.7 4.4e-10 39.3 0.2 2.3 1 1 1 2 2 2 2 Amidohydrolase family Thioredoxin_2 PF13098.1 EXF75567.1 - 0.048 13.8 0.0 0.08 13.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like domain MFS_1 PF07690.11 EXF75568.1 - 6.3e-34 117.2 34.7 8.8e-34 116.7 23.8 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.15 EXF75568.1 - 0.00095 17.3 9.0 0.1 10.6 2.2 2.2 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF1228 PF06779.9 EXF75568.1 - 0.0064 16.4 7.2 1.1 9.3 0.1 3.8 2 2 1 4 4 4 2 Protein of unknown function (DUF1228) MFS_1 PF07690.11 EXF75569.1 - 1.8e-33 115.7 36.8 1.8e-33 115.7 25.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2 PF00096.21 EXF75570.1 - 0.037 14.3 2.9 0.054 13.8 2.0 1.3 1 0 0 1 1 1 0 Zinc finger, C2H2 type DUF629 PF04780.7 EXF75570.1 - 0.11 11.0 0.0 0.11 10.9 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF629) zf-C2H2_4 PF13894.1 EXF75570.1 - 0.46 10.9 2.6 0.74 10.2 1.8 1.3 1 0 0 1 1 1 0 C2H2-type zinc finger zf-BED PF02892.10 EXF75570.1 - 6.5 6.5 5.9 13 5.6 4.1 1.5 1 1 0 1 1 1 0 BED zinc finger Methyltransf_23 PF13489.1 EXF75572.1 - 1.2e-21 77.0 0.0 2.6e-21 76.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF75572.1 - 2.6e-07 30.3 0.0 5e-06 26.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF75572.1 - 7.4e-07 29.7 0.0 9.5e-06 26.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF75572.1 - 3e-06 27.6 0.0 5.8e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF75572.1 - 0.00079 18.8 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EXF75572.1 - 0.0017 18.8 0.0 0.016 15.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EXF75572.1 - 0.028 14.3 0.0 0.09 12.7 0.0 1.8 2 0 0 2 2 2 0 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EXF75572.1 - 0.075 13.3 0.0 0.28 11.5 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EXF75572.1 - 0.094 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EXF75572.1 - 0.11 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Glyco_hydro_43 PF04616.9 EXF75573.1 - 1.1e-38 133.0 3.5 1.5e-38 132.5 2.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DinI PF06183.8 EXF75573.1 - 0.088 12.8 0.0 21 5.1 0.0 2.5 2 0 0 2 2 2 0 DinI-like family AA_permease_2 PF13520.1 EXF75574.1 - 2.3e-39 135.1 55.5 6e-38 130.4 38.5 2.0 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF75574.1 - 1.6e-23 82.8 49.2 1.7e-18 66.2 22.2 2.0 2 0 0 2 2 2 2 Amino acid permease DUF2592 PF10766.4 EXF75574.1 - 0.022 14.1 7.1 0.38 10.1 1.6 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2592) p450 PF00067.17 EXF75577.1 - 5e-40 137.4 0.0 1.7e-39 135.6 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Aminotran_3 PF00202.16 EXF75578.1 - 3.8e-30 104.9 0.0 2.5e-24 85.7 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-III Fungal_trans_2 PF11951.3 EXF75579.1 - 1e-19 70.4 1.5 1.8e-19 69.5 1.0 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain Arginase PF00491.16 EXF75580.1 - 1.5e-80 270.4 0.0 2.2e-80 269.9 0.0 1.1 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EXF75580.1 - 0.047 13.8 0.3 0.13 12.4 0.1 1.8 1 1 1 2 2 2 0 UPF0489 domain MatE PF01554.13 EXF75581.1 - 4.6e-47 159.6 22.7 8.8e-26 90.4 4.9 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EXF75581.1 - 3.8e-10 39.7 9.6 7.7e-09 35.5 2.1 4.1 5 0 0 5 5 5 2 Polysaccharide biosynthesis C-terminal domain MFS_1 PF07690.11 EXF75582.1 - 5.5e-22 77.9 9.7 7.4e-22 77.5 6.8 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF75582.1 - 8.7e-10 37.7 7.4 1.1e-09 37.4 5.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EXF75582.1 - 2.7e-05 22.5 1.9 3.3e-05 22.2 1.4 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF70 PF01901.11 EXF75582.1 - 0.051 12.6 0.0 0.069 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF70 PD40 PF07676.7 EXF75583.1 - 0.11 12.2 0.0 0.33 10.6 0.0 1.9 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Proteasome_A_N PF10584.4 EXF75583.1 - 0.12 11.7 0.2 0.29 10.5 0.1 1.7 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature ATP-synt_C PF00137.16 EXF75585.1 - 5.7e-11 42.1 21.1 9.8e-09 34.9 3.7 2.0 2 0 0 2 2 2 2 ATP synthase subunit C DUF4395 PF14340.1 EXF75585.1 - 0.028 14.4 1.1 0.037 14.0 0.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4395) Asp PF00026.18 EXF75586.1 - 2.6e-73 247.0 7.2 3.1e-73 246.8 5.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EXF75586.1 - 8.6e-12 45.3 1.7 8.6e-12 45.3 1.2 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EXF75586.1 - 9.2e-06 26.0 4.4 0.003 18.0 0.3 4.1 3 2 1 4 4 4 1 Aspartyl protease TAXi_C PF14541.1 EXF75586.1 - 2.6e-05 23.8 0.1 0.00024 20.6 0.0 2.1 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.1 EXF75586.1 - 0.087 12.6 0.0 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease MFS_1 PF07690.11 EXF75587.1 - 7.9e-39 133.3 49.0 2.9e-38 131.4 33.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.11 EXF75588.1 - 2.9e-49 167.6 53.7 6.4e-49 166.5 35.9 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EXF75588.1 - 7.5e-16 57.4 18.7 7.5e-16 57.4 12.9 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EXF75588.1 - 4.5e-13 48.5 10.6 4.5e-13 48.5 7.4 3.4 2 1 1 3 3 3 1 Sugar (and other) transporter Med21 PF11221.3 EXF75588.1 - 0.37 10.7 1.3 1.6 8.7 1.0 1.9 1 1 1 2 2 2 0 Subunit 21 of Mediator complex Alpha_GJ PF03229.8 EXF75588.1 - 9.8 6.5 13.0 7.6 6.8 7.6 2.0 2 0 0 2 2 2 0 Alphavirus glycoprotein J Mur_ligase_C PF02875.16 EXF75589.1 - 0.0013 18.7 0.1 0.015 15.2 0.0 2.9 3 0 0 3 3 3 1 Mur ligase family, glutamate ligase domain Mur_ligase_M PF08245.7 EXF75590.1 - 0.00037 20.5 0.0 0.0039 17.2 0.0 2.1 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.16 EXF75590.1 - 0.0087 16.0 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain Mitofilin PF09731.4 EXF75591.1 - 4.3e-149 497.8 10.9 6e-149 497.3 7.6 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein YlqD PF11068.3 EXF75591.1 - 0.87 9.6 8.9 3 7.8 2.6 2.3 1 1 1 2 2 2 0 YlqD protein TMP_2 PF06791.8 EXF75591.1 - 1.6 8.2 6.7 1.2 8.6 2.2 2.2 2 0 0 2 2 2 0 Prophage tail length tape measure protein AAA_13 PF13166.1 EXF75591.1 - 1.7 7.0 11.3 1.7 7.0 7.0 1.4 1 1 0 1 1 1 0 AAA domain Ras PF00071.17 EXF75592.1 - 1.8e-58 196.4 0.2 2.1e-58 196.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EXF75592.1 - 3.8e-19 69.3 0.1 6.1e-19 68.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EXF75592.1 - 8e-15 54.5 0.0 9.6e-15 54.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EXF75592.1 - 1.1e-07 31.2 0.0 1.3e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EXF75592.1 - 1.2e-07 31.3 0.0 1.7e-07 30.8 0.0 1.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EXF75592.1 - 1.2e-05 25.2 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EXF75592.1 - 0.022 14.8 0.0 2.6 8.1 0.0 2.5 1 1 1 2 2 2 0 AAA domain DUF258 PF03193.11 EXF75592.1 - 0.037 13.2 0.2 0.14 11.3 0.0 2.0 2 1 0 3 3 3 0 Protein of unknown function, DUF258 Amidase02_C PF12123.3 EXF75592.1 - 0.12 12.0 0.0 0.82 9.3 0.0 2.1 2 0 0 2 2 2 0 N-acetylmuramoyl-l-alanine amidase G-alpha PF00503.15 EXF75592.1 - 0.14 10.7 0.2 11 4.6 0.1 2.2 1 1 1 2 2 2 0 G-protein alpha subunit AAA_16 PF13191.1 EXF75592.1 - 0.15 12.0 0.3 0.37 10.7 0.2 1.8 1 1 0 1 1 1 0 AAA ATPase domain Syja_N PF02383.13 EXF75593.1 - 6.4e-88 294.5 0.0 8.2e-88 294.2 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain Esterase_phd PF10503.4 EXF75594.1 - 1.1e-21 77.1 0.3 1.5e-21 76.6 0.2 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.13 EXF75594.1 - 4.6e-13 48.5 16.5 2.6e-12 46.1 11.4 2.5 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 EXF75594.1 - 6.8e-11 41.7 0.8 9.7e-11 41.2 0.5 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EXF75594.1 - 7e-05 22.6 0.1 0.00011 22.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF75594.1 - 0.00026 20.6 0.2 0.00041 19.9 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EXF75594.1 - 0.0019 18.0 0.0 0.003 17.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EXF75594.1 - 0.0053 15.5 0.2 0.0053 15.5 0.1 1.7 2 0 0 2 2 2 1 Carboxylesterase family Esterase PF00756.15 EXF75594.1 - 0.019 14.4 0.8 0.026 13.9 0.6 1.2 1 0 0 1 1 1 0 Putative esterase Abhydrolase_3 PF07859.8 EXF75594.1 - 0.057 12.9 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EXF75594.1 - 0.1 12.0 0.1 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase MFS_1 PF07690.11 EXF75595.1 - 7.3e-20 70.9 24.5 7.3e-20 70.9 17.0 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily CENP-B_N PF04218.8 EXF75595.1 - 0.0019 17.5 0.0 0.0038 16.6 0.0 1.4 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain GST_C_3 PF14497.1 EXF75597.1 - 3.8e-08 33.6 0.0 7.9e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EXF75597.1 - 0.01 15.6 0.0 0.02 14.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain UPF0183 PF03676.9 EXF75598.1 - 1.8e-38 132.2 0.0 2.4e-24 85.6 0.0 4.6 4 1 0 4 4 4 4 Uncharacterised protein family (UPF0183) Kinesin PF00225.18 EXF75599.1 - 1.3e-107 359.4 0.1 1.3e-107 359.4 0.1 2.2 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bind PF13931.1 EXF75599.1 - 2.1e-06 27.9 0.6 2.1e-06 27.9 0.4 4.8 4 1 1 5 5 5 1 Kinesin-associated microtubule-binding Acetyltransf_1 PF00583.19 EXF75599.1 - 4e-05 23.5 0.1 9.5e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF75599.1 - 0.063 13.4 0.2 0.17 12.0 0.1 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Apolipoprotein PF01442.13 EXF75599.1 - 4.9 6.6 62.4 0.046 13.2 11.4 4.9 1 1 3 4 4 4 0 Apolipoprotein A1/A4/E domain HAD_2 PF13419.1 EXF75600.1 - 2e-22 80.2 0.0 1.1e-21 77.8 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Aldedh PF00171.17 EXF75602.1 - 3.8e-166 553.0 1.1 4.3e-166 552.8 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family tRNA-synt_1 PF00133.17 EXF75603.1 - 1.8e-156 521.6 0.0 2.6e-156 521.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EXF75603.1 - 6.4e-19 67.8 0.0 1.9e-10 39.9 0.0 3.2 3 0 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EXF75603.1 - 4.2e-18 65.5 0.0 8.4e-18 64.5 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA zf-FPG_IleRS PF06827.9 EXF75603.1 - 1.7e-05 24.2 4.7 1.7e-05 24.2 3.3 2.0 2 0 0 2 2 2 1 Zinc finger found in FPG and IleRS tRNA-synt_1e PF01406.14 EXF75603.1 - 0.078 12.0 0.0 12 4.9 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Mitoc_L55 PF09776.4 EXF75604.1 - 0.059 12.9 0.7 0.14 11.7 0.5 1.6 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L55 Milton PF12448.3 EXF75605.1 - 0.038 14.1 0.6 0.045 13.9 0.4 1.1 1 0 0 1 1 1 0 Kinesin associated protein RRM_5 PF13893.1 EXF75606.1 - 5.4e-08 32.5 0.1 1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EXF75606.1 - 7e-08 31.9 0.1 1.9e-07 30.6 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF75606.1 - 8.7e-06 25.6 0.1 2e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1631 PF07793.6 EXF75606.1 - 2.9 5.9 7.4 4.6 5.2 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Citrate_synt PF00285.16 EXF75607.1 - 2.3e-103 345.6 0.0 2.8e-103 345.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Eclosion PF04736.7 EXF75607.1 - 0.011 15.1 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone Mito_carr PF00153.22 EXF75608.1 - 5.2e-28 96.6 5.4 2.9e-12 46.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.13 EXF75609.1 - 8.2e-15 54.3 0.7 1.3e-14 53.7 0.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF75609.1 - 5.2e-08 32.6 11.9 8.2e-08 32.0 8.2 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain UbiD PF01977.11 EXF75610.1 - 5e-130 433.6 0.0 6e-130 433.3 0.0 1.1 1 0 0 1 1 1 1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase MarR_2 PF12802.2 EXF75610.1 - 0.074 12.7 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 MarR family Flavoprotein PF02441.14 EXF75611.1 - 6.2e-29 100.2 0.4 8.1e-29 99.9 0.3 1.1 1 0 0 1 1 1 1 Flavoprotein Fungal_trans PF04082.13 EXF75612.1 - 1.4e-12 47.0 0.0 4.3e-12 45.4 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain BCS1_N PF08740.6 EXF75613.1 - 1.3e-28 99.8 0.1 3e-28 98.7 0.1 1.5 1 0 0 1 1 1 1 BCS1 N terminal MFS_1 PF07690.11 EXF75613.1 - 1.7e-27 96.0 48.2 2.5e-21 75.7 17.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA PF00004.24 EXF75613.1 - 4.5e-22 78.6 0.0 1.1e-21 77.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MFS_2 PF13347.1 EXF75613.1 - 1.4e-12 46.7 14.3 3.1e-09 35.7 0.6 2.3 1 1 0 2 2 2 2 MFS/sugar transport protein RuvB_N PF05496.7 EXF75613.1 - 4.1e-05 22.7 0.0 7.2e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus MFS_1_like PF12832.2 EXF75613.1 - 0.0024 17.6 2.0 0.45 10.3 0.0 3.3 3 0 0 3 3 3 1 MFS_1 like family AAA_17 PF13207.1 EXF75613.1 - 0.0061 17.3 0.0 0.019 15.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EXF75613.1 - 0.018 15.3 0.0 0.031 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EXF75613.1 - 0.05 13.7 0.0 0.13 12.4 0.0 1.7 1 0 0 1 1 1 0 RNA helicase DUF815 PF05673.8 EXF75613.1 - 0.057 12.3 0.0 0.089 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_16 PF13191.1 EXF75613.1 - 0.088 12.7 0.0 0.26 11.2 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 EXF75613.1 - 0.092 12.4 0.0 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EXF75613.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain YL1_C PF08265.6 EXF75613.1 - 0.13 11.8 0.2 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain TIP49 PF06068.8 EXF75613.1 - 0.32 9.6 0.0 0.51 9.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus BNR_2 PF13088.1 EXF75615.1 - 3.1e-09 36.5 1.4 0.00013 21.3 0.1 2.5 2 1 0 2 2 2 2 BNR repeat-like domain Epimerase PF01370.16 EXF75616.1 - 5.6e-15 55.4 0.0 9e-15 54.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EXF75616.1 - 3.6e-09 35.9 1.0 0.00022 20.2 0.0 2.3 1 1 0 2 2 2 2 Male sterility protein NmrA PF05368.8 EXF75616.1 - 0.00011 21.5 0.3 0.00021 20.6 0.1 1.5 1 1 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EXF75616.1 - 0.00013 20.8 0.2 0.0002 20.1 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EXF75616.1 - 0.00075 19.5 0.4 0.0011 18.9 0.3 1.4 1 1 0 1 1 1 1 NADH(P)-binding tRNA_Me_trans PF03054.11 EXF75616.1 - 0.012 14.1 0.2 0.016 13.8 0.1 1.1 1 0 0 1 1 1 0 tRNA methyl transferase Polysacc_synt_2 PF02719.10 EXF75616.1 - 0.077 11.8 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MFS_1 PF07690.11 EXF75617.1 - 1.8e-31 109.1 14.7 5e-27 94.5 8.9 2.7 2 1 1 3 3 3 2 Major Facilitator Superfamily DUF2427 PF10348.4 EXF75617.1 - 1.4 8.5 8.0 0.22 11.1 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) Fungal_trans PF04082.13 EXF75618.1 - 1.2e-14 53.7 1.0 1.2e-14 53.7 0.7 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Bac_rhamnosid PF05592.6 EXF75619.1 - 1e-20 73.4 0.1 9.1e-13 47.2 0.1 3.0 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 EXF75619.1 - 0.0016 17.2 0.0 0.0025 16.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 DUF1080 PF06439.6 EXF75619.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1080) Sugar_tr PF00083.19 EXF75620.1 - 8.2e-88 294.9 27.5 1e-87 294.6 19.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF75620.1 - 4.3e-15 55.2 46.6 5.7e-09 35.1 13.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Transaldolase PF00923.14 EXF75621.1 - 2.1e-32 112.3 0.0 3.3e-32 111.7 0.0 1.2 1 0 0 1 1 1 1 Transaldolase HLH PF00010.21 EXF75622.1 - 0.00094 18.8 0.1 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain SRR1 PF07985.7 EXF75623.1 - 0.0043 16.9 0.0 0.0072 16.2 0.0 1.4 1 0 0 1 1 1 1 SRR1 PFU PF09070.6 EXF75625.1 - 1.1e-43 147.9 0.1 2e-43 147.0 0.1 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.6 EXF75625.1 - 1.2e-41 142.2 0.0 1.9e-41 141.6 0.0 1.3 1 0 0 1 1 1 1 PUL domain WD40 PF00400.27 EXF75625.1 - 3.7e-38 128.0 7.7 4.4e-07 29.5 0.0 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 EXF75625.1 - 0.017 14.8 0.0 4.8 6.9 0.0 3.5 2 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 EXF75626.1 - 1.6e-35 119.7 2.7 5.1e-11 42.0 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat Abhydrolase_3 PF07859.8 EXF75627.1 - 8.5e-21 74.4 0.1 1.4e-20 73.8 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF75627.1 - 2.8e-06 27.1 0.0 5.8e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EXF75627.1 - 5.3e-05 22.2 0.0 7.8e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Peptidase_S9 PF00326.16 EXF75627.1 - 6.7e-05 22.1 0.0 0.00031 20.0 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family COesterase PF00135.23 EXF75627.1 - 0.00021 20.1 0.0 0.00044 19.0 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Chlorophyllase PF07224.6 EXF75627.1 - 0.0013 17.5 0.0 0.0018 17.1 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase AXE1 PF05448.7 EXF75627.1 - 0.0037 15.8 0.1 0.036 12.5 0.0 2.0 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 EXF75627.1 - 0.034 13.5 0.0 0.061 12.7 0.0 1.4 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 EXF75627.1 - 0.065 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Glycophorin_A PF01102.13 EXF75628.1 - 0.0014 18.4 0.1 0.0095 15.6 0.3 2.0 2 0 0 2 2 2 1 Glycophorin A Rax2 PF12768.2 EXF75628.1 - 0.027 13.6 0.1 0.039 13.1 0.1 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity VSP PF03302.8 EXF75628.1 - 0.042 12.4 2.0 0.057 12.0 1.4 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Gly-zipper_OmpA PF13436.1 EXF75628.1 - 0.062 12.9 2.0 0.12 12.0 1.4 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Syndecan PF01034.15 EXF75628.1 - 0.095 12.3 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Syndecan domain Med3 PF11593.3 EXF75628.1 - 0.16 11.1 2.7 0.2 10.8 1.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3328 PF11807.3 EXF75629.1 - 4.2e-18 65.8 0.2 8.6e-18 64.8 0.2 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) Glyco_hydro_17 PF00332.13 EXF75630.1 - 2.1e-08 33.5 1.6 0.0026 16.8 0.2 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 17 Peroxidase_2 PF01328.12 EXF75632.1 - 1.3e-19 69.9 0.0 2e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase, family 2 bZIP_1 PF00170.16 EXF75633.1 - 1.3e-10 41.1 7.9 2.1e-10 40.4 5.5 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EXF75633.1 - 7.9e-07 28.8 9.8 1.3e-06 28.1 6.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EXF75633.1 - 0.00064 19.9 5.6 0.00064 19.9 3.9 1.5 2 0 0 2 2 2 1 bZIP Maf transcription factor Adaptin_binding PF10199.4 EXF75633.1 - 0.051 13.8 1.5 0.055 13.7 1.1 1.3 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 TMF_DNA_bd PF12329.3 EXF75633.1 - 0.15 11.8 2.8 0.25 11.1 1.9 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Takusan PF04822.8 EXF75633.1 - 0.16 11.7 2.3 0.32 10.7 1.6 1.4 1 0 0 1 1 1 0 Takusan DUF4140 PF13600.1 EXF75633.1 - 1.9 8.9 4.5 3.9 7.9 1.9 2.0 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Fungal_trans_2 PF11951.3 EXF75634.1 - 0.0018 16.9 5.4 0.014 14.0 3.8 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EXF75635.1 - 4.1e-11 42.2 0.1 7.9e-11 41.3 0.1 1.3 1 1 0 1 1 1 1 Fungal specific transcription factor domain PP_kinase_N PF13089.1 EXF75636.1 - 0.19 11.8 4.0 0.22 11.6 0.1 2.6 1 1 2 3 3 3 0 Polyphosphate kinase N-terminal domain HsbA PF12296.3 EXF75637.1 - 7.2e-09 35.5 0.8 1e-08 35.0 0.5 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A OTT_1508_deam PF14441.1 EXF75638.1 - 1.3e-07 31.5 0.0 7e-06 25.9 0.0 2.6 1 1 1 2 2 2 2 OTT_1508-like deaminase Tannase PF07519.6 EXF75639.1 - 3e-95 319.7 3.1 5.3e-95 318.8 2.2 1.4 1 1 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 EXF75639.1 - 0.017 14.3 0.1 1.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EXF75639.1 - 0.023 14.6 0.0 0.049 13.5 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family IMS PF00817.15 EXF75640.1 - 1.3e-42 145.1 0.1 3.1e-42 143.8 0.1 1.7 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EXF75640.1 - 3.9e-16 59.1 0.4 1.1e-15 57.7 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EXF75640.1 - 0.00079 19.3 0.1 0.0023 17.8 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif Arg_repressor PF01316.16 EXF75640.1 - 0.33 10.5 5.0 0.78 9.3 2.6 2.1 2 0 0 2 2 2 0 Arginine repressor, DNA binding domain RGS PF00615.14 EXF75641.1 - 4.4e-06 26.7 0.0 1.6e-05 24.9 0.0 1.9 1 1 0 1 1 1 1 Regulator of G protein signaling domain Herpes_gE PF02480.11 EXF75641.1 - 0.051 11.8 0.3 0.68 8.1 0.1 2.1 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E p450 PF00067.17 EXF75642.1 - 4e-38 131.1 0.0 3.6e-24 85.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Peptidase_MA_2 PF13485.1 EXF75645.1 - 2.3e-07 30.9 0.2 4.2e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily DUF3433 PF11915.3 EXF75646.1 - 8.2e-28 96.4 18.7 7.2e-22 77.3 1.2 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) DUF3500 PF12006.3 EXF75647.1 - 4.4e-107 357.6 0.0 5.1e-107 357.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) FAA_hydrolase PF01557.13 EXF75648.1 - 1.9e-51 174.6 0.0 2.6e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Mitofilin PF09731.4 EXF75649.1 - 0.013 14.1 0.0 0.013 14.1 0.0 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Lys-AminoMut_A PF09043.6 EXF75649.1 - 0.024 12.7 0.0 0.028 12.5 0.0 1.0 1 0 0 1 1 1 0 D-Lysine 5,6-aminomutase alpha subunit B12-binding PF02310.14 EXF75649.1 - 0.028 14.2 0.1 0.042 13.7 0.1 1.3 1 0 0 1 1 1 0 B12 binding domain FAD_binding_3 PF01494.14 EXF75650.1 - 1.9e-22 79.8 0.0 2.9e-22 79.2 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF75650.1 - 1.4e-13 50.4 0.0 1.9e-06 27.0 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EXF75650.1 - 1.7e-07 31.5 0.3 0.0001 22.6 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF75650.1 - 2.2e-06 27.5 0.7 6.2e-06 26.1 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EXF75650.1 - 4.2e-05 22.5 1.6 7.3e-05 21.7 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EXF75650.1 - 4.7e-05 23.3 0.0 0.00013 21.9 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF75650.1 - 5.3e-05 21.8 0.7 0.00042 18.9 0.5 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EXF75650.1 - 0.00024 21.2 0.0 0.00044 20.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF75650.1 - 0.00086 18.2 0.6 0.0024 16.7 0.5 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A SE PF08491.5 EXF75650.1 - 0.0011 17.8 0.0 0.0026 16.6 0.0 1.6 1 1 0 1 1 1 1 Squalene epoxidase FAD_oxidored PF12831.2 EXF75650.1 - 0.0016 17.6 1.2 0.0023 17.0 0.9 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EXF75650.1 - 0.0022 17.1 0.4 0.0033 16.5 0.3 1.2 1 0 0 1 1 1 1 Thi4 family 3HCDH_N PF02737.13 EXF75650.1 - 0.0041 16.8 0.3 0.0068 16.0 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 EXF75650.1 - 0.0086 14.7 0.4 0.08 11.5 0.1 2.3 2 1 1 3 3 3 1 Tryptophan halogenase DUF3603 PF12227.3 EXF75650.1 - 0.017 14.2 0.0 0.031 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3603) Lycopene_cycl PF05834.7 EXF75650.1 - 0.055 12.3 0.0 0.11 11.3 0.0 1.5 1 1 0 1 1 1 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.9 EXF75650.1 - 0.098 12.0 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF3533 PF12051.3 EXF75651.1 - 2.5e-117 391.8 13.5 2.9e-117 391.6 9.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) ABC2_membrane_3 PF12698.2 EXF75651.1 - 4.3e-08 32.5 14.8 7e-08 31.8 10.2 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein MFS_1 PF07690.11 EXF75652.1 - 2.3e-34 118.6 32.9 2.3e-34 118.6 22.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily HET PF06985.6 EXF75652.1 - 3.9e-22 78.9 7.4 4.6e-19 68.9 1.0 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF3533 PF12051.3 EXF75653.1 - 2.1e-93 313.1 9.4 2.5e-93 312.8 6.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3533) ABC2_membrane_3 PF12698.2 EXF75653.1 - 3 6.7 21.0 0.35 9.8 10.6 2.2 2 1 0 2 2 2 0 ABC-2 family transporter protein ABC_tran PF00005.22 EXF75654.1 - 9.9e-47 158.6 0.8 1.2e-24 87.2 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EXF75654.1 - 8e-28 97.4 53.8 7.2e-19 68.0 22.3 3.0 2 1 0 3 3 3 2 ABC-2 family transporter protein AAA_21 PF13304.1 EXF75654.1 - 1.1e-20 74.8 4.6 2.4e-05 24.4 0.0 4.4 3 1 1 4 4 4 4 AAA domain AAA_29 PF13555.1 EXF75654.1 - 6.2e-10 38.4 2.1 7.5e-05 22.1 0.2 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EXF75654.1 - 8.1e-08 32.8 4.9 0.001 19.4 0.2 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EXF75654.1 - 4.1e-07 29.4 4.7 0.12 11.6 0.1 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EXF75654.1 - 1.2e-05 24.5 0.7 0.06 12.5 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EXF75654.1 - 0.00019 21.4 1.0 0.26 11.2 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_15 PF13175.1 EXF75654.1 - 0.0011 18.0 0.0 1.2 8.0 0.0 3.0 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EXF75654.1 - 0.014 15.5 0.2 5.3 7.1 0.1 3.3 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EXF75654.1 - 0.014 14.7 0.5 4.5 6.6 0.1 3.0 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.7 EXF75654.1 - 0.015 14.4 0.1 3 6.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 EXF75654.1 - 0.035 13.8 2.0 10 5.9 0.0 3.6 3 0 0 3 3 3 0 Part of AAA domain SRP54 PF00448.17 EXF75654.1 - 0.036 13.4 0.1 7 6.0 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_30 PF13604.1 EXF75654.1 - 0.052 13.1 2.7 3.1 7.3 0.1 2.9 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.1 EXF75654.1 - 0.059 13.2 0.1 16 5.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 EXF75654.1 - 0.2 10.3 0.0 1.4 7.4 0.0 2.0 2 0 0 2 2 2 0 G-protein alpha subunit DUF87 PF01935.12 EXF75654.1 - 0.21 11.3 1.5 15 5.3 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_13 PF13166.1 EXF75654.1 - 0.28 9.6 0.1 4.3 5.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EXF75654.1 - 0.34 9.7 0.1 8.6 5.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain AIG1 PF04548.11 EXF75654.1 - 0.8 8.7 2.4 2.5 7.1 0.3 2.3 2 0 0 2 2 2 0 AIG1 family Methyltransf_6 PF03737.10 EXF75655.1 - 3.3e-30 105.0 0.1 3.8e-30 104.8 0.1 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase Amidohydro_2 PF04909.9 EXF75656.1 - 3e-10 40.1 0.3 3.6e-10 39.8 0.2 1.3 1 0 0 1 1 1 1 Amidohydrolase Mycobact_memb PF05423.8 EXF75656.1 - 0.021 14.5 0.1 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Mycobacterium membrane protein Zn_clus PF00172.13 EXF75657.1 - 5e-09 35.9 7.8 8.4e-09 35.2 5.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF75657.1 - 0.0012 17.8 0.1 0.0045 15.8 0.1 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Aconitase PF00330.15 EXF75658.1 - 2.1e-132 441.9 0.0 7.8e-132 440.0 0.0 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EXF75658.1 - 3.5e-38 130.6 0.0 6.1e-38 129.8 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DAP_B PF07930.7 EXF75658.1 - 0.018 14.7 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 D-aminopeptidase, domain B MFS_1 PF07690.11 EXF75659.1 - 3e-34 118.2 21.3 3e-34 118.2 14.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily FAD_binding_3 PF01494.14 EXF75660.1 - 7.3e-15 54.8 2.2 6.4e-14 51.7 1.5 2.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF75660.1 - 0.00011 21.2 0.5 0.00031 19.7 0.4 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF75660.1 - 0.00076 19.4 0.9 0.0021 18.0 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EXF75660.1 - 0.0011 17.8 0.0 0.0079 15.0 0.0 2.1 1 1 1 2 2 2 1 Squalene epoxidase FAD_binding_2 PF00890.19 EXF75660.1 - 0.0015 17.4 0.5 0.003 16.4 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EXF75660.1 - 0.005 16.7 0.2 0.0099 15.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF75660.1 - 0.0071 14.8 0.1 0.011 14.2 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.17 EXF75660.1 - 0.071 11.9 0.8 0.1 11.4 0.5 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 EXF75660.1 - 0.14 11.8 0.0 0.33 10.6 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Methyltransf_11 PF08241.7 EXF75661.1 - 9.6e-06 26.0 0.0 2.1e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF75661.1 - 1.2e-05 25.8 0.0 1.7e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF75661.1 - 1.7e-05 25.1 0.0 2.4e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF75661.1 - 3.1e-05 23.6 0.0 4.1e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF75661.1 - 0.00018 21.2 0.0 0.00028 20.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EXF75661.1 - 0.02 14.3 0.0 0.03 13.7 0.0 1.4 1 1 0 1 1 1 0 Nodulation protein S (NodS) DUF3146 PF11344.3 EXF75661.1 - 0.074 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3146) Oxidored_FMN PF00724.15 EXF75662.1 - 2.2e-93 312.9 0.0 2.5e-93 312.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.19 EXF75662.1 - 0.01 15.1 0.0 1.6 7.9 0.0 2.2 1 1 1 2 2 2 0 Xylose isomerase-like TIM barrel Abhydrolase_6 PF12697.2 EXF75663.1 - 1.6e-26 93.5 0.2 1.9e-26 93.3 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF75663.1 - 5.6e-17 61.8 0.0 8.4e-17 61.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF75663.1 - 0.0028 17.2 0.0 1.9 8.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold PGAP1 PF07819.8 EXF75663.1 - 0.0077 15.8 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 EXF75663.1 - 0.025 14.8 0.0 0.047 13.8 0.0 1.5 2 0 0 2 2 2 0 Thioesterase domain Ser_hydrolase PF06821.8 EXF75663.1 - 0.04 13.5 0.0 0.061 12.9 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase DUF676 PF05057.9 EXF75663.1 - 0.07 12.4 0.0 0.17 11.1 0.0 1.5 2 0 0 2 2 2 0 Putative serine esterase (DUF676) HTH_16 PF12645.2 EXF75663.1 - 0.077 12.9 0.1 0.15 12.0 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3089 PF11288.3 EXF75663.1 - 0.086 11.9 0.0 0.29 10.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) UPF0227 PF05728.7 EXF75663.1 - 0.14 11.9 0.0 0.31 10.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) GFO_IDH_MocA PF01408.17 EXF75664.1 - 1.3e-23 83.8 0.0 2.3e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EXF75664.1 - 7.4e-07 29.5 0.0 1.5e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA_C PF02894.12 EXF75664.1 - 0.026 14.3 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain Zn-ribbon_8 PF09723.5 EXF75664.1 - 0.22 11.5 1.4 2.3 8.2 0.1 2.3 2 0 0 2 2 2 0 Zinc ribbon domain DUF1349 PF07081.6 EXF75665.1 - 9e-18 64.2 0.0 1.3e-17 63.7 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1349) Aminotran_3 PF00202.16 EXF75666.1 - 1.6e-78 263.9 0.0 2e-78 263.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III MFS_1 PF07690.11 EXF75667.1 - 5e-25 87.9 48.5 1.3e-15 56.9 22.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EXF75667.1 - 0.039 12.4 16.9 0.089 11.2 11.0 2.2 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like HAD_2 PF13419.1 EXF75668.1 - 9.8e-18 64.9 0.0 1.3e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EXF75668.1 - 4e-08 32.8 0.1 1.2e-07 31.3 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.21 EXF75668.1 - 7.6e-06 26.4 0.0 2.6e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase GMC_oxred_N PF00732.14 EXF75669.1 - 3.1e-56 190.6 0.0 4.9e-56 190.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF75669.1 - 1.1e-31 110.1 0.4 2.1e-31 109.1 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase Pyr_redox_3 PF13738.1 EXF75669.1 - 4.8e-07 30.0 0.4 0.0041 17.2 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF75669.1 - 0.00017 21.5 0.1 0.00048 20.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF75669.1 - 0.00087 18.2 0.2 0.002 17.1 0.1 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF75669.1 - 0.0012 17.7 0.3 0.029 13.2 0.2 2.3 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EXF75669.1 - 0.0032 16.4 0.1 0.0049 15.8 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein TrkA_N PF02254.13 EXF75669.1 - 0.0088 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain FAD_binding_3 PF01494.14 EXF75669.1 - 0.024 13.7 1.1 0.033 13.2 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 EXF75669.1 - 0.038 12.4 0.0 0.07 11.5 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EXF75669.1 - 0.06 12.4 0.0 0.14 11.2 0.0 1.5 1 0 0 1 1 1 0 Thi4 family DUF4328 PF14219.1 EXF75670.1 - 0.0032 16.7 3.2 0.0056 15.9 2.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4328) DUF3176 PF11374.3 EXF75670.1 - 0.037 13.8 1.2 0.099 12.5 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3176) Sugar_tr PF00083.19 EXF75671.1 - 9.2e-57 192.5 26.1 1.1e-56 192.3 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF75671.1 - 1.6e-13 50.0 35.9 1.6e-13 50.0 24.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF75671.1 - 5.2e-05 21.6 2.5 5.2e-05 21.6 1.8 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_43 PF04616.9 EXF75672.1 - 4.6e-64 216.2 0.0 6.4e-64 215.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Abhydrolase_2 PF02230.11 EXF75673.1 - 1.6e-25 89.8 0.0 1.2e-24 86.9 0.0 2.0 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EXF75673.1 - 1.8e-06 27.7 0.0 3.1e-06 26.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF75673.1 - 2.8e-05 24.1 0.2 0.011 15.6 0.1 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EXF75673.1 - 0.0015 18.0 0.0 0.0036 16.7 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) LIP PF03583.9 EXF75673.1 - 0.0028 16.8 0.0 0.0043 16.2 0.0 1.3 1 0 0 1 1 1 1 Secretory lipase Peptidase_S9 PF00326.16 EXF75673.1 - 0.0039 16.4 0.0 0.0097 15.1 0.0 1.6 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EXF75673.1 - 0.022 14.3 0.1 2 7.9 0.0 2.4 1 1 0 2 2 2 0 alpha/beta hydrolase fold MFS_1 PF07690.11 EXF75675.1 - 1.6e-21 76.4 81.8 2.3e-16 59.4 32.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_S10 PF00450.17 EXF75676.1 - 1.2e-87 294.8 0.1 1.5e-87 294.4 0.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase DUF872 PF05915.7 EXF75677.1 - 0.14 12.0 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF3079 PF11278.3 EXF75677.1 - 0.23 11.0 1.4 0.25 10.9 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3079) Fructosamin_kin PF03881.9 EXF75678.1 - 8.8e-10 38.0 0.0 1.5e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase Dioxygenase_C PF00775.16 EXF75678.1 - 1.6e-08 34.0 0.6 7.7e-08 31.8 0.4 2.0 1 1 0 1 1 1 1 Dioxygenase APH PF01636.18 EXF75678.1 - 0.0049 16.6 0.0 0.012 15.3 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family NTP_transf_3 PF12804.2 EXF75679.1 - 2.3e-21 76.5 0.2 4.3e-21 75.6 0.1 1.4 1 1 0 1 1 1 1 MobA-like NTP transferase domain SLAC1 PF03595.12 EXF75680.1 - 6.1e-50 169.7 28.9 7.2e-50 169.4 20.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel 7tm_4 PF13853.1 EXF75680.1 - 2.1 8.1 6.3 4.2 7.1 0.2 2.8 3 0 0 3 3 3 0 Olfactory receptor F-box-like PF12937.2 EXF75681.1 - 0.0027 17.4 0.1 0.02 14.6 0.1 2.4 2 0 0 2 2 2 1 F-box-like Peptidase_S8 PF00082.17 EXF75682.1 - 1.3e-45 155.7 16.2 2.1e-45 155.0 11.2 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EXF75682.1 - 0.00012 22.5 0.4 0.00036 21.0 0.3 1.8 2 0 0 2 2 2 1 Peptidase inhibitor I9 SQS_PSY PF00494.14 EXF75683.1 - 5.5e-37 127.5 0.0 1.7e-36 125.9 0.0 1.7 2 0 0 2 2 2 1 Squalene/phytoene synthase RmlD_sub_bind PF04321.12 EXF75684.1 - 4.1e-14 52.1 0.0 9.7e-14 50.9 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EXF75684.1 - 8.5e-11 41.7 0.0 2.2e-10 40.3 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EXF75684.1 - 0.0025 16.7 0.0 0.0042 16.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EXF75684.1 - 0.043 12.5 0.0 0.096 11.3 0.0 1.4 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family C2-set_2 PF08205.7 EXF75684.1 - 0.052 13.4 0.5 0.14 12.1 0.1 1.7 1 1 1 2 2 2 0 CD80-like C2-set immunoglobulin domain Macro PF01661.16 EXF75684.1 - 0.069 13.0 0.3 0.56 10.1 0.1 2.4 3 0 0 3 3 3 0 Macro domain adh_short PF00106.20 EXF75684.1 - 0.15 12.0 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DnaJ-X PF14308.1 EXF75685.1 - 2.1e-72 242.6 1.2 2.1e-72 242.6 0.8 1.9 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 EXF75685.1 - 5.7e-27 93.2 1.1 1.2e-26 92.1 0.7 1.6 1 0 0 1 1 1 1 DnaJ domain Isochorismatase PF00857.15 EXF75686.1 - 2.9e-25 89.2 0.0 3.6e-25 88.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF3580 PF12117.3 EXF75686.1 - 0.065 13.1 0.1 0.11 12.4 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3580) efThoc1 PF11957.3 EXF75686.1 - 0.11 10.9 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 THO complex subunit 1 transcription elongation factor DUF3883 PF13020.1 EXF75687.1 - 0.0002 21.0 0.0 0.0005 19.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) HATPase_c_3 PF13589.1 EXF75687.1 - 0.0022 17.6 0.0 0.0062 16.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cyt-b5 PF00173.23 EXF75689.1 - 6.1e-16 57.9 0.0 8.7e-16 57.4 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FHA PF00498.21 EXF75690.1 - 1.4e-08 34.7 0.1 2.7e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain Mannosyl_trans PF05007.8 EXF75691.1 - 2.4e-75 253.5 12.6 3.2e-75 253.1 8.8 1.2 1 0 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EXF75691.1 - 4.3e-13 48.8 0.1 4.3e-13 48.8 0.0 2.1 1 1 2 3 3 3 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 EXF75691.1 - 1.5e-06 27.9 21.3 1.5e-06 27.9 14.7 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2029) Translin PF01997.11 EXF75692.1 - 1.6e-51 174.7 0.2 1.8e-51 174.5 0.1 1.0 1 0 0 1 1 1 1 Translin family FliJ PF02050.11 EXF75692.1 - 0.011 15.7 0.2 0.023 14.7 0.1 1.5 1 0 0 1 1 1 0 Flagellar FliJ protein NPV_P10 PF05531.7 EXF75692.1 - 0.071 13.3 0.1 0.42 10.9 0.0 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Syntaxin PF00804.20 EXF75692.1 - 0.12 12.5 0.6 0.22 11.7 0.2 1.6 2 0 0 2 2 2 0 Syntaxin AAA PF00004.24 EXF75693.1 - 0.17 12.0 0.5 0.87 9.7 0.4 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RTA1 PF04479.8 EXF75694.1 - 6.4e-50 169.7 10.4 1e-49 169.0 7.2 1.3 1 0 0 1 1 1 1 RTA1 like protein Kei1 PF08552.6 EXF75694.1 - 0.0038 16.9 0.4 0.0038 16.9 0.3 2.0 2 0 0 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 DUF373 PF04123.8 EXF75694.1 - 9.1 5.1 11.9 1.2 8.0 4.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF373) AAT PF03417.11 EXF75695.1 - 4.8e-27 94.8 0.0 5.8e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase NAAA-beta PF15508.1 EXF75695.1 - 0.0036 17.6 0.0 0.0059 16.9 0.0 1.3 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Tricorn_C1 PF14684.1 EXF75695.1 - 0.14 12.0 0.1 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Tricorn protease C1 domain Sugar_tr PF00083.19 EXF75696.1 - 1.6e-72 244.5 23.5 2.2e-72 244.1 16.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter p450 PF00067.17 EXF75696.1 - 3.2e-65 220.4 0.0 9.8e-65 218.8 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EXF75696.1 - 3.2e-24 85.3 26.7 7.7e-24 84.0 11.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF667 PF05018.8 EXF75696.1 - 0.11 11.6 0.7 0.2 10.8 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF667) NmrA PF05368.8 EXF75697.1 - 2e-25 89.4 0.0 2.6e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF75697.1 - 8.6e-08 32.3 0.6 1.7e-07 31.4 0.4 1.6 1 1 0 1 1 1 1 NADH(P)-binding FAD_binding_4 PF01565.18 EXF75698.1 - 1e-24 86.5 0.4 1.6e-24 85.9 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain DLH PF01738.13 EXF75699.1 - 1.4e-22 80.0 0.0 2.3e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family adh_short PF00106.20 EXF75699.1 - 3.4e-20 72.6 1.4 4.8e-20 72.1 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF75699.1 - 3.6e-19 69.5 0.0 6.7e-19 68.6 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF75699.1 - 9e-07 28.7 0.6 1.5e-06 28.0 0.4 1.3 1 0 0 1 1 1 1 KR domain Abhydrolase_5 PF12695.2 EXF75699.1 - 6.3e-05 22.7 0.5 0.00022 20.9 0.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Epimerase PF01370.16 EXF75699.1 - 0.0019 17.7 0.1 0.0046 16.4 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EXF75699.1 - 0.014 15.0 0.3 0.024 14.2 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Abhydrolase_1 PF00561.15 EXF75699.1 - 0.079 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold EthD PF07110.6 EXF75700.1 - 1.7e-05 25.6 0.2 4e-05 24.4 0.1 1.6 1 1 0 1 1 1 1 EthD domain Glyco_hydro_43 PF04616.9 EXF75701.1 - 2e-56 191.1 7.9 2.8e-56 190.7 5.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1080 PF06439.6 EXF75701.1 - 1.2e-07 31.8 0.1 2.5e-07 30.7 0.1 1.5 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1080) Glyco_hydro_32N PF00251.15 EXF75701.1 - 0.00026 20.4 3.3 0.00048 19.5 2.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Laminin_G_3 PF13385.1 EXF75701.1 - 0.022 15.0 0.3 0.022 15.0 0.2 2.7 3 0 0 3 3 3 0 Concanavalin A-like lectin/glucanases superfamily DUF377 PF04041.8 EXF75701.1 - 0.21 10.3 1.2 2.4 6.8 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF377) AzlC PF03591.9 EXF75702.1 - 0.015 15.2 3.3 0.015 15.2 2.3 2.9 3 0 0 3 3 3 0 AzlC protein MmgE_PrpD PF03972.9 EXF75703.1 - 3.3e-72 243.0 0.0 3.8e-72 242.8 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DUF2650 PF10853.3 EXF75704.1 - 0.53 9.7 5.9 1.5 8.3 4.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2650) Glyco_hydro_10 PF00331.15 EXF75705.1 - 1.5e-98 329.8 0.1 1.7e-98 329.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 CBM_1 PF00734.13 EXF75705.1 - 3.3e-14 52.2 9.8 3.3e-14 52.2 6.8 2.0 2 0 0 2 2 2 1 Fungal cellulose binding domain CENP-Q PF13094.1 EXF75706.1 - 0.1 12.6 0.1 7.8 6.4 0.0 2.3 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit FlxA PF14282.1 EXF75706.1 - 0.15 12.0 2.4 3.3 7.6 0.2 2.2 2 0 0 2 2 2 0 FlxA-like protein Glyco_hydro_12 PF01670.11 EXF75707.1 - 8.9e-17 61.2 2.6 2.5e-15 56.5 0.8 2.3 1 1 1 2 2 2 2 Glycosyl hydrolase family 12 DUF1498 PF07385.7 EXF75707.1 - 0.13 11.4 0.8 0.25 10.4 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1498) TrkH PF02386.11 EXF75709.1 - 8.6e-92 307.4 12.0 8.2e-88 294.3 3.5 2.8 2 1 0 2 2 2 2 Cation transport protein OTT_1508_deam PF14441.1 EXF75710.1 - 1.6e-19 70.1 0.0 3.2e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase CIA30 PF08547.7 EXF75711.1 - 0.0098 15.7 0.0 0.012 15.5 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Abhydrolase_5 PF12695.2 EXF75712.1 - 5.5e-13 48.9 0.0 1.5e-11 44.2 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF75712.1 - 8.8e-13 48.6 0.1 1.2e-12 48.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EXF75712.1 - 0.0002 20.6 0.0 0.0034 16.7 0.0 2.4 2 1 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 EXF75712.1 - 0.0017 17.8 0.0 0.0023 17.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF1100 PF06500.6 EXF75712.1 - 0.003 16.1 0.0 0.0043 15.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) AXE1 PF05448.7 EXF75712.1 - 0.036 12.5 0.0 0.12 10.8 0.0 1.7 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 EXF75712.1 - 0.068 12.8 0.0 0.26 10.9 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Apolipoprotein PF01442.13 EXF75713.1 - 0.00037 20.0 4.3 1.9 7.9 4.6 3.6 1 1 2 3 3 3 2 Apolipoprotein A1/A4/E domain OHCU_decarbox PF09349.5 EXF75713.1 - 0.024 14.9 1.1 1.8 8.8 0.0 2.8 1 1 2 3 3 3 0 OHCU decarboxylase ApoL PF05461.6 EXF75713.1 - 0.067 12.4 9.7 0.14 11.4 0.0 3.8 3 1 0 4 4 4 0 Apolipoprotein L DUF148 PF02520.12 EXF75713.1 - 0.084 12.6 0.1 0.084 12.6 0.1 3.9 2 1 2 4 4 4 0 Domain of unknown function DUF148 Senescence PF06911.7 EXF75713.1 - 0.089 12.4 8.1 1.6 8.3 0.0 3.8 3 2 0 3 3 3 0 Senescence-associated protein DUF883 PF05957.8 EXF75713.1 - 0.99 9.8 18.8 25 5.3 1.5 5.8 3 1 3 6 6 6 0 Bacterial protein of unknown function (DUF883) DUF2762 PF10960.3 EXF75713.1 - 2 8.1 8.7 36 4.1 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2762) Phasin PF05597.6 EXF75713.1 - 4.6 7.0 24.9 0.87 9.3 0.6 4.9 3 1 1 5 5 5 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Lactamase_B PF00753.22 EXF75714.1 - 5.7e-21 75.0 1.9 8.8e-21 74.4 1.3 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EXF75714.1 - 3e-06 26.9 0.1 4.6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Pyr_redox_3 PF13738.1 EXF75715.1 - 4.5e-18 66.0 0.0 1.5e-17 64.3 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EXF75715.1 - 2.3e-13 49.2 0.0 2.6e-12 45.7 0.0 2.5 2 2 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EXF75715.1 - 2.1e-08 34.0 0.0 7.8e-08 32.2 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EXF75715.1 - 6.1e-06 25.3 0.0 0.0029 16.5 0.0 3.3 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EXF75715.1 - 0.0025 17.6 0.1 0.29 10.9 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Sda PF08970.5 EXF75715.1 - 0.072 12.5 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Sporulation inhibitor A CPSase_L_chain PF00289.17 EXF75715.1 - 0.12 12.5 0.1 12 6.0 0.0 2.8 3 0 0 3 3 3 0 Carbamoyl-phosphate synthase L chain, N-terminal domain Zn_clus PF00172.13 EXF75716.1 - 2.3e-07 30.6 5.7 3.6e-07 29.9 4.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 EXF75717.1 - 1e-59 202.3 0.0 1.2e-59 202.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 AMP-binding PF00501.23 EXF75718.1 - 2.3e-82 276.6 0.1 4.7e-82 275.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EXF75718.1 - 5.9e-78 261.8 0.0 1.6e-77 260.4 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EXF75718.1 - 6.6e-55 186.6 0.7 1.2e-54 185.7 0.2 1.6 2 0 0 2 2 1 1 Acyl transferase domain KR PF08659.5 EXF75718.1 - 8.3e-55 185.2 0.0 2.7e-50 170.5 0.0 2.9 2 0 0 2 2 2 2 KR domain adh_short PF00106.20 EXF75718.1 - 3e-46 157.3 0.0 3.6e-40 137.6 0.0 2.9 2 0 0 2 2 2 2 short chain dehydrogenase Condensation PF00668.15 EXF75718.1 - 1.2e-42 145.8 0.0 2.2e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 Condensation domain NAD_binding_4 PF07993.7 EXF75718.1 - 2.5e-41 141.2 0.0 1.3e-40 138.8 0.0 2.1 2 0 0 2 2 2 1 Male sterility protein PS-DH PF14765.1 EXF75718.1 - 2.4e-39 135.2 0.4 4.1e-39 134.5 0.3 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EXF75718.1 - 5.4e-32 110.1 0.2 1.5e-31 108.7 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EXF75718.1 - 1.3e-18 67.3 0.0 4.1e-18 65.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EXF75718.1 - 1.8e-15 56.9 0.5 6e-10 39.2 0.1 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.16 EXF75718.1 - 2e-15 56.8 0.0 3e-14 53.0 0.0 2.7 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.1 EXF75718.1 - 3.1e-14 52.9 0.0 9e-14 51.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF75718.1 - 3.8e-13 49.7 0.0 1e-12 48.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF75718.1 - 2.3e-10 40.2 0.0 5.3e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF75718.1 - 3.6e-10 40.4 0.0 8.9e-09 35.9 0.0 3.1 3 0 0 3 3 2 1 Methyltransferase domain 3Beta_HSD PF01073.14 EXF75718.1 - 1e-09 37.5 0.0 1.2e-08 34.0 0.0 2.3 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_25 PF13649.1 EXF75718.1 - 3.7e-08 33.6 0.0 1.4e-07 31.7 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF75718.1 - 2e-07 30.3 0.0 4.1e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family HxxPF_rpt PF13745.1 EXF75718.1 - 1.6e-06 28.2 0.3 1.2e-05 25.5 0.1 2.5 2 0 0 2 2 2 1 HxxPF-repeated domain Thiolase_N PF00108.18 EXF75718.1 - 6.6e-06 25.2 0.0 4.2e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain MTS PF05175.9 EXF75718.1 - 2.3e-05 23.8 0.0 5.7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EXF75718.1 - 0.00034 20.1 0.0 0.00076 18.9 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EXF75718.1 - 0.0006 19.8 0.0 0.0024 17.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EXF75718.1 - 0.0018 17.3 0.0 0.0036 16.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase DUF938 PF06080.7 EXF75718.1 - 0.018 14.5 0.0 0.046 13.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF938) NmrA PF05368.8 EXF75718.1 - 0.025 13.8 0.0 0.4 9.8 0.0 2.5 2 0 0 2 2 2 0 NmrA-like family Semialdhyde_dh PF01118.19 EXF75718.1 - 0.052 13.8 0.1 0.45 10.8 0.0 2.7 3 0 0 3 3 2 0 Semialdehyde dehydrogenase, NAD binding domain NNMT_PNMT_TEMT PF01234.12 EXF75718.1 - 0.12 11.3 0.0 0.56 9.1 0.0 2.0 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family TRAM_LAG1_CLN8 PF03798.11 EXF75719.1 - 1.3e-32 112.9 15.2 1.3e-32 112.9 10.5 1.9 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EXF75719.1 - 2.3e-25 87.8 0.2 6.7e-25 86.3 0.0 1.9 2 0 0 2 2 2 1 TRAM1-like protein DUF4234 PF14018.1 EXF75719.1 - 0.41 10.4 6.4 3 7.6 1.2 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) TRAM_LAG1_CLN8 PF03798.11 EXF75720.1 - 2.9e-38 131.4 14.0 2.9e-38 131.4 9.7 1.4 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EXF75720.1 - 7.6e-20 70.1 0.1 1.6e-19 69.1 0.0 1.6 1 0 0 1 1 1 1 TRAM1-like protein Mito_carr PF00153.22 EXF75721.1 - 4.7e-44 148.0 8.0 1.7e-18 66.0 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein FAM70 PF14967.1 EXF75721.1 - 0.019 14.2 0.1 0.03 13.5 0.1 1.3 1 0 0 1 1 1 0 FAM70 protein E7 PF00527.13 EXF75721.1 - 0.13 12.4 0.4 0.22 11.7 0.3 1.3 1 0 0 1 1 1 0 E7 protein, Early protein SnoaL PF07366.7 EXF75722.1 - 1.9e-26 92.1 0.3 1.6e-16 60.0 0.0 2.1 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EXF75722.1 - 1.4e-09 38.3 0.1 0.00035 20.9 0.0 2.3 2 0 0 2 2 2 2 SnoaL-like domain DUF4440 PF14534.1 EXF75722.1 - 0.1 12.8 0.1 0.47 10.6 0.0 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4440) Glyco_hydro_61 PF03443.9 EXF75723.1 - 2e-50 171.6 0.0 2.3e-50 171.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Pkinase PF00069.20 EXF75724.1 - 7.3e-23 81.0 0.0 8.4e-23 80.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF75724.1 - 2.4e-09 36.6 0.0 4e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EXF75724.1 - 0.016 13.9 0.0 0.025 13.3 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3631 PF12307.3 EXF75725.1 - 0.034 14.0 0.5 0.17 11.8 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3631) DUF2017 PF09438.5 EXF75725.1 - 0.057 12.9 0.1 0.067 12.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2017) Glyco_hydro_28 PF00295.12 EXF75726.1 - 3.1e-41 141.4 2.4 4.3e-41 140.9 1.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase PF03211.8 EXF75727.1 - 4.4e-63 212.5 7.6 5.1e-63 212.3 5.3 1.0 1 0 0 1 1 1 1 Pectate lyase IBR PF01485.16 EXF75728.1 - 1.2e-06 28.2 24.1 0.00014 21.7 7.0 4.0 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 EXF75728.1 - 0.00014 21.5 7.3 0.00014 21.5 5.1 3.8 4 0 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.1 EXF75728.1 - 0.00019 21.0 7.1 0.00019 21.0 4.9 4.1 3 2 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EXF75728.1 - 0.00049 20.0 7.7 0.00049 20.0 5.4 3.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EXF75728.1 - 0.0044 16.6 7.5 0.0044 16.6 5.2 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) adh_short PF00106.20 EXF75729.1 - 1.3e-32 113.0 0.2 1.8e-32 112.6 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF75729.1 - 2e-20 73.5 0.1 2.4e-20 73.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF75729.1 - 2.4e-13 50.1 0.1 3.6e-13 49.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF75729.1 - 0.0028 17.1 1.4 0.016 14.6 1.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EXF75729.1 - 0.016 14.1 0.1 0.022 13.6 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HAD PF12710.2 EXF75729.1 - 0.042 14.0 0.4 1.2 9.2 0.3 2.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase 3Beta_HSD PF01073.14 EXF75729.1 - 0.045 12.4 0.4 0.063 11.9 0.2 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family PCEMA1 PF07418.6 EXF75729.1 - 0.14 11.5 0.0 0.18 11.1 0.0 1.3 1 1 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 PMSR PF01625.16 EXF75730.1 - 3.8e-58 195.7 0.2 4.5e-58 195.5 0.1 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Bax1-I PF01027.15 EXF75731.1 - 5e-33 114.4 10.9 7.2e-33 113.9 7.6 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 cNMP_binding PF00027.24 EXF75733.1 - 3.4e-36 122.9 0.0 6.7e-18 64.2 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain LRR_6 PF13516.1 EXF75733.1 - 6e-16 56.6 7.3 0.061 13.4 0.0 8.6 8 0 0 8 8 8 4 Leucine Rich repeat LRR_8 PF13855.1 EXF75733.1 - 2.1e-07 30.6 2.3 0.018 14.7 0.2 4.5 2 1 3 5 5 5 3 Leucine rich repeat LRR_1 PF00560.28 EXF75733.1 - 6.1e-07 28.6 7.7 5.1 7.5 0.1 8.1 6 2 1 7 7 7 2 Leucine Rich Repeat LRR_4 PF12799.2 EXF75733.1 - 4.1e-06 26.2 0.4 0.69 9.5 0.0 4.3 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EXF75733.1 - 6.4e-05 22.5 1.0 0.00033 20.3 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EXF75733.1 - 0.002 17.7 0.1 0.002 17.7 0.1 2.8 3 0 0 3 3 3 1 F-box domain Cupin_3 PF05899.7 EXF75733.1 - 0.14 11.5 0.0 8.5 5.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF861) DUF605 PF04652.11 EXF75733.1 - 0.38 10.0 18.8 0.037 13.4 6.3 2.2 2 0 0 2 2 2 0 Vta1 like LRR_7 PF13504.1 EXF75733.1 - 4.5 7.9 16.3 29 5.4 0.0 6.2 7 0 0 7 7 7 0 Leucine rich repeat HET PF06985.6 EXF75735.1 - 3.5e-22 79.0 6.1 1.9e-19 70.2 0.6 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) NPP1 PF05630.6 EXF75737.1 - 1.2e-09 38.2 0.7 1.8e-09 37.6 0.1 1.6 2 0 0 2 2 2 1 Necrosis inducing protein (NPP1) DUF2235 PF09994.4 EXF75738.1 - 2.1e-68 230.6 0.1 3.3e-35 121.8 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EXF75738.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 EXF75739.1 - 2.8e-29 101.9 26.8 2.8e-29 101.9 18.5 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1237 PF06824.6 EXF75740.1 - 3.4e-176 585.9 0.0 4e-176 585.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Ank_2 PF12796.2 EXF75742.1 - 1.9e-98 323.0 13.2 3.6e-20 72.1 0.0 4.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EXF75742.1 - 8.7e-68 220.9 9.5 1.2e-07 31.2 0.0 9.4 9 0 0 9 9 9 9 Ankyrin repeat Ank_4 PF13637.1 EXF75742.1 - 2.4e-48 161.6 1.3 9.7e-09 35.5 0.0 6.0 3 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF75742.1 - 9.8e-46 149.1 1.0 0.00021 21.2 0.0 9.5 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.1 EXF75742.1 - 8.3e-42 140.2 10.8 4.5e-09 36.2 0.0 7.0 2 1 6 8 8 8 8 Ankyrin repeats (many copies) TPR_11 PF13414.1 EXF75743.1 - 1.7e-57 190.9 25.4 1.3e-16 59.9 1.0 6.3 5 1 0 6 6 6 6 TPR repeat TPR_1 PF00515.23 EXF75743.1 - 2.5e-45 150.2 16.1 2.1e-07 30.2 0.0 9.1 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 EXF75743.1 - 2.4e-37 123.8 15.6 6.1e-05 22.6 0.0 9.5 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_12 PF13424.1 EXF75743.1 - 6.5e-21 74.0 11.6 1.4e-13 50.5 0.4 5.5 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EXF75743.1 - 8.4e-20 70.9 4.9 0.0012 19.5 0.0 6.5 3 3 5 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.1 EXF75743.1 - 8.7e-19 66.3 4.9 0.25 12.0 0.0 8.6 5 3 4 9 9 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 EXF75743.1 - 1.7e-18 64.8 16.7 0.00046 19.7 0.2 8.1 6 2 2 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.1 EXF75743.1 - 2.3e-15 55.4 6.0 0.0025 17.8 0.1 7.8 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 EXF75743.1 - 4e-14 52.6 6.7 8.4e-06 26.0 0.0 6.0 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 EXF75743.1 - 1.1e-12 46.7 10.2 0.0014 18.2 0.0 8.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 EXF75743.1 - 5.3e-10 39.0 0.1 0.0079 16.0 0.0 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EXF75743.1 - 2.1e-05 24.6 14.3 1.9 9.1 0.0 7.5 8 0 0 8 8 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EXF75743.1 - 4.6e-05 23.4 5.4 0.0012 18.9 1.1 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EXF75743.1 - 0.00042 20.1 0.8 0.061 13.2 0.0 4.2 5 0 0 5 5 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 EXF75743.1 - 0.0018 17.4 1.1 4 6.7 0.0 4.3 5 0 0 5 5 5 1 SHNi-TPR Fis1_TPR_C PF14853.1 EXF75743.1 - 0.017 15.0 0.8 26 4.7 0.1 5.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.13 EXF75743.1 - 0.11 12.4 0.3 0.11 12.4 0.2 6.1 6 0 0 6 6 5 0 MIT (microtubule interacting and transport) domain RPN7 PF10602.4 EXF75743.1 - 0.19 11.0 5.7 0.69 9.2 0.5 3.8 3 2 1 4 4 4 0 26S proteasome subunit RPN7 TPR_3 PF07720.7 EXF75743.1 - 0.21 11.4 0.1 0.21 11.4 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1910 PF08928.5 EXF75743.1 - 7.6 6.5 6.8 0.86 9.6 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1910) Peptidase_C12 PF01088.16 EXF75744.1 - 2.1e-55 187.2 0.0 2.5e-55 186.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyoxalase_2 PF12681.2 EXF75744.1 - 0.1 13.2 0.1 0.18 12.4 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase-like domain Hemerythrin PF01814.18 EXF75745.1 - 5.4e-11 42.7 0.0 6.9e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Ctr PF04145.10 EXF75746.1 - 2e-43 147.8 0.7 2.8e-43 147.4 0.5 1.2 1 0 0 1 1 1 1 Ctr copper transporter family TauD PF02668.11 EXF75747.1 - 2e-44 152.1 0.4 2.4e-44 151.9 0.3 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Zeta_toxin PF06414.7 EXF75747.1 - 0.098 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin zf-C2H2_4 PF13894.1 EXF75748.1 - 0.00027 21.0 20.6 0.66 10.4 0.0 6.0 5 2 1 6 6 6 3 C2H2-type zinc finger zf-CHCC PF10276.4 EXF75748.1 - 0.099 12.4 3.8 6.6 6.6 0.1 2.9 2 0 0 2 2 2 0 Zinc-finger domain zf-C2H2_jaz PF12171.3 EXF75748.1 - 3.8 7.7 13.7 5 7.4 0.1 4.6 4 1 1 5 5 5 0 Zinc-finger double-stranded RNA-binding zf-Di19 PF05605.7 EXF75748.1 - 5.9 7.0 16.1 8.8 6.5 2.1 4.2 2 1 2 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding Zn_clus PF00172.13 EXF75749.1 - 1.3e-06 28.2 8.8 2.6e-06 27.2 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3716 PF12511.3 EXF75749.1 - 3.3 7.4 8.8 16 5.2 5.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3716) MFS_1 PF07690.11 EXF75750.1 - 1.3e-33 116.2 26.2 1.3e-33 116.2 18.1 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF1446 PF07287.6 EXF75751.1 - 1.5e-118 395.4 0.0 1.8e-118 395.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Fungal_trans PF04082.13 EXF75752.1 - 1.3e-18 66.8 0.0 2.8e-18 65.7 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF75752.1 - 2.5e-09 36.8 12.3 4.6e-09 36.0 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HrpB7 PF09486.5 EXF75752.1 - 0.0027 17.6 4.6 0.013 15.4 3.2 2.0 2 0 0 2 2 2 1 Bacterial type III secretion protein (HrpB7) DivIC PF04977.10 EXF75752.1 - 0.024 14.1 2.3 0.052 13.0 1.6 1.5 1 0 0 1 1 1 0 Septum formation initiator HeLo PF14479.1 EXF75752.1 - 0.028 14.1 0.5 0.053 13.2 0.4 1.4 1 0 0 1 1 1 0 Prion-inhibition and propagation Rab5-bind PF09311.6 EXF75752.1 - 0.049 13.5 5.7 0.11 12.3 4.0 1.5 1 0 0 1 1 1 0 Rabaptin-like protein DUF4250 PF14056.1 EXF75752.1 - 0.6 9.8 3.5 2.9 7.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) Peptidase_M28 PF04389.12 EXF75753.1 - 1.9e-34 118.9 0.0 3e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EXF75753.1 - 2.4e-16 59.2 0.1 5e-16 58.2 0.0 1.6 1 0 0 1 1 1 1 PA domain Zip PF02535.17 EXF75754.1 - 1.4e-44 152.3 13.9 1.4e-43 149.1 9.6 1.9 1 1 0 1 1 1 1 ZIP Zinc transporter MGC-24 PF05283.6 EXF75754.1 - 0.087 12.6 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) RNA_pol_Rpc34 PF05158.7 EXF75755.1 - 1.9e-99 332.9 0.0 2.4e-99 332.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpc34 subunit RPA_C PF08784.6 EXF75755.1 - 0.0037 17.6 0.0 0.052 13.9 0.0 2.6 2 0 0 2 2 2 1 Replication protein A C terminal B-block_TFIIIC PF04182.7 EXF75755.1 - 0.038 13.8 0.0 0.098 12.5 0.0 1.9 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC Rrf2 PF02082.15 EXF75755.1 - 0.091 12.8 0.0 4.8 7.3 0.0 2.5 3 0 0 3 3 3 0 Transcriptional regulator Pro_isomerase PF00160.16 EXF75756.1 - 8.4e-40 136.5 0.3 1.1e-39 136.1 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.15 EXF75757.1 - 4e-47 159.1 0.1 5.8e-47 158.6 0.1 1.2 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EXF75757.1 - 0.00045 19.0 0.0 0.00063 18.5 0.0 1.2 1 0 0 1 1 1 1 ANTH domain MARVEL PF01284.18 EXF75758.1 - 0.002 17.9 8.7 0.0033 17.2 6.1 1.3 1 0 0 1 1 1 1 Membrane-associating domain Peptidase_M1 PF01433.15 EXF75759.1 - 3.1e-133 444.6 2.3 4.4e-133 444.1 1.6 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EXF75759.1 - 1.5e-72 244.6 0.0 2.4e-72 243.9 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EXF75759.1 - 8.8e-21 74.2 1.4 8.8e-21 74.2 1.0 2.5 1 1 1 2 2 2 1 Peptidase MA superfamily DUF45 PF01863.12 EXF75759.1 - 0.039 13.7 0.3 0.25 11.0 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function DUF45 Tcp11 PF05794.8 EXF75760.1 - 1.2e-47 162.6 0.1 3.8e-47 161.0 0.0 1.8 2 0 0 2 2 2 1 T-complex protein 11 MCM PF00493.18 EXF75761.1 - 9.1e-135 448.7 0.4 1.5e-134 447.9 0.3 1.4 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EXF75761.1 - 9.5e-20 71.3 0.1 5.6e-19 68.8 0.0 2.3 3 0 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 EXF75761.1 - 2.7e-07 29.9 0.0 8.1e-07 28.4 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EXF75761.1 - 0.0018 17.7 0.0 0.0036 16.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EXF75761.1 - 0.0022 17.5 0.0 0.0079 15.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNase_H2_suC PF08615.6 EXF75762.1 - 2.3e-28 98.7 0.0 2.8e-28 98.4 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) CMAS PF02353.15 EXF75763.1 - 3.2e-74 249.4 0.0 8.5e-74 248.0 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EXF75763.1 - 2.7e-11 43.4 0.0 5.1e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF75763.1 - 3.6e-10 40.4 0.0 9.2e-10 39.1 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF75763.1 - 3.8e-09 36.9 0.0 7.3e-09 36.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF75763.1 - 1.5e-08 34.3 0.0 2.5e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF75763.1 - 6.6e-07 29.3 0.0 1.3e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF75763.1 - 1.4e-06 28.7 0.0 2.7e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EXF75763.1 - 0.0012 18.3 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_3 PF01596.12 EXF75763.1 - 0.0034 16.4 0.0 0.0055 15.7 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase MTS PF05175.9 EXF75763.1 - 0.0081 15.5 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain ADH_zinc_N PF00107.21 EXF75763.1 - 0.062 12.8 0.0 0.13 11.8 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase RNase_T PF00929.19 EXF75764.1 - 1.9e-24 86.8 0.0 2.9e-24 86.2 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EXF75764.1 - 0.0026 17.2 0.0 0.0052 16.2 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease Macoilin PF09726.4 EXF75764.1 - 2.8 6.1 8.3 3.8 5.6 5.7 1.1 1 0 0 1 1 1 0 Transmembrane protein MOZ_SAS PF01853.13 EXF75765.1 - 1.9e-84 281.6 0.2 2.8e-84 281.0 0.1 1.2 1 0 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EXF75765.1 - 1.2e-16 60.1 0.0 6.8e-16 57.7 0.0 2.2 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.1 EXF75765.1 - 0.069 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EXF75765.1 - 0.11 12.5 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family He_PIG_assoc PF10632.4 EXF75765.1 - 0.16 11.3 0.1 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 He_PIG associated, NEW1 domain of bacterial glycohydrolase Aminotran_1_2 PF00155.16 EXF75766.1 - 7.4e-13 48.1 0.0 1.3e-12 47.3 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EXF75766.1 - 3.8e-05 22.4 0.0 0.00024 19.7 0.0 1.9 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase F1F0-ATPsyn_F PF10791.4 EXF75769.1 - 1.4e-42 143.8 0.2 1.5e-42 143.6 0.2 1.0 1 0 0 1 1 1 1 Mitochondrial F1-F0 ATP synthase subunit F of fungi WRW PF10206.4 EXF75769.1 - 0.025 14.6 0.1 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f ETC_C1_NDUFA4 PF04800.7 EXF75770.1 - 3.7e-36 123.0 1.5 3.7e-36 123.0 1.0 1.5 2 0 0 2 2 2 1 ETC complex I subunit conserved region Copper-bind PF00127.15 EXF75770.1 - 0.03 14.5 0.0 0.063 13.5 0.0 1.5 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family CLTH PF10607.4 EXF75771.1 - 2e-32 111.8 0.0 3.2e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EXF75771.1 - 1.2e-09 37.6 0.0 2.8e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 LisH PRK PF00485.13 EXF75772.1 - 5.7e-47 159.8 0.0 6.6e-45 153.0 0.0 2.2 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family UPRTase PF14681.1 EXF75772.1 - 6e-42 143.1 0.0 9.1e-42 142.6 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase AAA_17 PF13207.1 EXF75772.1 - 2.2e-10 41.4 0.0 5.3e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EXF75772.1 - 4.5e-07 30.2 0.0 9.5e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 EXF75772.1 - 4.1e-05 23.2 0.0 8.3e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 EXF75772.1 - 5.5e-05 23.0 0.0 0.0006 19.7 0.0 2.2 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EXF75772.1 - 0.0016 18.7 0.2 0.0075 16.5 0.1 1.9 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 EXF75772.1 - 0.0058 16.1 0.1 0.014 14.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Pribosyltran PF00156.22 EXF75772.1 - 0.0095 15.6 0.2 0.065 12.9 0.0 2.3 3 0 0 3 3 3 1 Phosphoribosyl transferase domain MobB PF03205.9 EXF75772.1 - 0.011 15.4 0.0 0.044 13.5 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EXF75772.1 - 0.014 14.5 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 EXF75772.1 - 0.014 15.3 0.0 0.069 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.17 EXF75772.1 - 0.019 13.8 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain DUF87 PF01935.12 EXF75772.1 - 0.046 13.5 0.2 0.12 12.2 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EXF75772.1 - 0.095 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 EXF75772.1 - 0.14 11.8 0.1 0.43 10.2 0.0 1.8 2 0 0 2 2 2 0 NTPase Pyr_redox_2 PF07992.9 EXF75773.1 - 1.4e-22 80.6 0.0 1.9e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF75773.1 - 5.1e-16 58.8 0.0 6.6e-11 42.4 0.0 3.8 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.27 EXF75773.1 - 7.6e-06 24.8 0.2 1.6e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EXF75773.1 - 3.8e-05 23.2 0.4 0.00014 21.4 0.3 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_7 PF13499.1 EXF75773.1 - 5.1e-05 23.3 0.1 0.00014 21.9 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EXF75773.1 - 0.00047 19.3 1.0 0.001 18.2 0.7 1.5 1 0 0 1 1 1 1 EF hand Pyr_redox_3 PF13738.1 EXF75773.1 - 0.0033 17.5 0.0 0.45 10.5 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Flavin_Reduct PF01613.13 EXF75773.1 - 0.041 13.7 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 Flavin reductase like domain NIR_SIR PF01077.17 EXF75774.1 - 9.6e-54 180.9 0.1 8.8e-47 158.3 0.0 2.6 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.12 EXF75774.1 - 6e-31 105.8 0.0 1e-15 57.1 0.0 2.7 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain Flavodoxin_1 PF00258.20 EXF75774.1 - 7e-31 107.1 0.0 1.7e-30 105.8 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin POR_N PF01855.14 EXF75774.1 - 8.5e-09 35.2 0.2 2.1e-08 33.9 0.1 1.6 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Kei1 PF08552.6 EXF75775.1 - 1.1e-53 181.6 1.2 1.4e-53 181.4 0.8 1.1 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF2975 PF11188.3 EXF75775.1 - 0.0044 16.7 1.6 0.0064 16.2 0.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2975) Ras PF00071.17 EXF75776.1 - 4.2e-57 192.0 0.6 5.5e-57 191.6 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EXF75776.1 - 1.2e-19 70.9 0.2 2.2e-19 70.0 0.0 1.5 2 0 0 2 2 1 1 Miro-like protein Arf PF00025.16 EXF75776.1 - 6.2e-17 61.3 0.2 8.5e-17 60.9 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EXF75776.1 - 2.1e-08 33.8 0.1 1.1e-07 31.4 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EXF75776.1 - 4.5e-06 25.9 0.3 5.7e-06 25.6 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EXF75776.1 - 1.7e-05 24.7 0.0 3.3e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EXF75776.1 - 2.6e-05 23.5 0.1 4.6e-05 22.7 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 EXF75776.1 - 0.02 14.8 0.0 0.27 11.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EXF75776.1 - 0.022 14.3 0.2 0.072 12.6 0.0 1.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_14 PF13173.1 EXF75776.1 - 0.025 14.4 0.3 0.047 13.6 0.2 1.5 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.18 EXF75776.1 - 0.025 14.3 0.2 3.1 7.6 0.0 2.6 2 1 0 2 2 2 0 Dynamin family Arch_ATPase PF01637.13 EXF75776.1 - 0.049 13.3 0.0 0.072 12.7 0.0 1.4 1 1 0 1 1 1 0 Archaeal ATPase MobB PF03205.9 EXF75776.1 - 0.087 12.5 0.2 4.1 7.0 0.0 2.3 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EXF75776.1 - 0.13 12.4 0.0 1.3 9.1 0.0 2.4 1 1 0 1 1 1 0 AAA domain Nop53 PF07767.6 EXF75777.1 - 6.8e-99 331.4 22.9 8.7e-99 331.1 15.9 1.1 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Fungal_trans PF04082.13 EXF75778.1 - 1.4e-34 119.1 11.7 2.7e-24 85.4 0.9 2.7 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF75778.1 - 4.4e-06 26.5 8.8 1.5e-05 24.7 6.1 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AhpC-TSA_2 PF13911.1 EXF75780.1 - 6.1e-12 45.4 0.0 1.1e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme PAP_assoc PF03828.14 EXF75781.1 - 4.3e-18 65.0 0.1 1.1e-17 63.7 0.1 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EXF75781.1 - 2e-05 24.8 0.0 3.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain adh_short PF00106.20 EXF75783.1 - 2.5e-29 102.3 2.1 3.7e-29 101.7 1.4 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF75783.1 - 2.4e-10 40.5 0.1 3.3e-10 40.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF75783.1 - 5.1e-10 39.3 1.0 9.7e-10 38.3 0.3 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EXF75783.1 - 0.0003 20.3 0.1 0.00033 20.1 0.1 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EXF75783.1 - 0.0017 17.3 0.1 0.0024 16.8 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.13 EXF75783.1 - 0.0019 17.8 0.5 0.0031 17.1 0.4 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EXF75783.1 - 0.034 14.1 0.5 0.063 13.2 0.3 1.4 1 0 0 1 1 1 0 TrkA-N domain DFP PF04127.10 EXF75783.1 - 0.095 12.3 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein 3Beta_HSD PF01073.14 EXF75783.1 - 0.1 11.2 0.2 0.14 10.8 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family WCCH PF03716.9 EXF75784.1 - 0.021 14.2 0.1 0.021 14.2 0.1 3.9 4 0 0 4 4 4 0 WCCH motif DUF3405 PF11885.3 EXF75785.1 - 1.7e-211 702.7 4.8 2.1e-211 702.4 3.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) EMP24_GP25L PF01105.19 EXF75786.1 - 1e-44 152.4 0.0 1.2e-44 152.2 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Dioxygenase_C PF00775.16 EXF75786.1 - 0.0059 15.8 0.0 0.0088 15.3 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase Arf PF00025.16 EXF75787.1 - 2.5e-80 267.8 0.3 2.8e-80 267.6 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EXF75787.1 - 1.6e-14 53.5 0.0 2e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EXF75787.1 - 2.4e-13 49.8 0.0 2.6e-13 49.6 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EXF75787.1 - 2.2e-12 46.3 2.0 2.5e-09 36.3 0.5 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EXF75787.1 - 3.5e-11 42.6 0.0 4.3e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EXF75787.1 - 1.2e-08 35.4 0.0 1.8e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EXF75787.1 - 2.5e-06 27.4 0.0 3.3e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.13 EXF75787.1 - 0.009 15.1 0.7 0.02 13.9 0.5 1.7 1 1 0 1 1 1 1 6-phosphofructo-2-kinase GTP_EFTU PF00009.22 EXF75787.1 - 0.012 15.0 0.2 0.093 12.1 0.0 1.9 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EXF75787.1 - 0.04 13.7 0.2 0.097 12.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_2 PF07724.9 EXF75788.1 - 4.4e-44 150.3 0.0 5.9e-43 146.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EXF75788.1 - 1.9e-23 82.1 0.1 6.1e-23 80.5 0.1 2.0 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EXF75788.1 - 1e-18 67.8 0.1 1.1e-09 38.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EXF75788.1 - 1.2e-11 44.5 0.0 1.7e-08 34.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EXF75788.1 - 2.6e-10 40.5 9.5 0.00097 19.1 0.0 5.2 3 2 1 5 5 5 3 AAA ATPase domain AAA_22 PF13401.1 EXF75788.1 - 4.3e-09 36.6 0.2 0.0013 18.8 0.0 3.2 2 1 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 EXF75788.1 - 1.1e-06 28.2 0.4 0.00054 19.4 0.0 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain Arch_ATPase PF01637.13 EXF75788.1 - 1.1e-05 25.2 8.4 0.19 11.4 0.0 4.7 2 2 1 4 4 4 2 Archaeal ATPase NACHT PF05729.7 EXF75788.1 - 1.3e-05 24.9 0.2 0.09 12.4 0.1 2.9 2 1 0 2 2 2 2 NACHT domain AAA_14 PF13173.1 EXF75788.1 - 1.5e-05 24.8 0.0 0.16 11.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EXF75788.1 - 5.9e-05 23.3 4.6 0.15 12.3 0.0 3.6 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EXF75788.1 - 0.0005 19.7 0.0 0.05 13.3 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain ABC_tran PF00005.22 EXF75788.1 - 0.00064 20.0 1.4 0.26 11.5 0.0 3.4 3 0 0 3 3 3 1 ABC transporter MobB PF03205.9 EXF75788.1 - 0.00078 19.1 0.1 0.27 10.9 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EXF75788.1 - 0.00086 18.7 0.0 0.77 9.1 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_17 PF13207.1 EXF75788.1 - 0.00087 20.0 9.8 0.026 15.3 0.2 4.0 3 2 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EXF75788.1 - 0.0039 17.0 0.0 4.1 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EXF75788.1 - 0.004 16.5 0.6 1.1 8.6 0.0 2.9 2 2 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EXF75788.1 - 0.0052 16.9 0.0 0.95 9.6 0.0 3.0 2 1 0 2 2 2 1 RNA helicase PhoH PF02562.11 EXF75788.1 - 0.0099 15.1 0.1 0.21 10.7 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.1 EXF75788.1 - 0.0099 15.8 0.5 11 5.8 0.0 3.6 3 1 0 3 3 3 0 AAA domain AAA_10 PF12846.2 EXF75788.1 - 0.01 15.3 0.3 0.66 9.3 0.0 3.7 2 2 1 3 3 3 0 AAA-like domain Miro PF08477.8 EXF75788.1 - 0.014 15.8 0.1 0.9 10.0 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_24 PF13479.1 EXF75788.1 - 0.018 14.6 0.1 2 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EXF75788.1 - 0.022 14.2 0.0 0.47 9.8 0.0 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TrwB_AAD_bind PF10412.4 EXF75788.1 - 0.027 13.1 0.1 2.5 6.6 0.0 2.8 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain DUF258 PF03193.11 EXF75788.1 - 0.027 13.6 0.0 3.2 6.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Mg_chelatase PF01078.16 EXF75788.1 - 0.04 13.0 0.2 2 7.4 0.0 2.9 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI ResIII PF04851.10 EXF75788.1 - 0.045 13.5 3.0 7.8 6.2 0.0 3.3 3 1 1 4 4 3 0 Type III restriction enzyme, res subunit PduV-EutP PF10662.4 EXF75788.1 - 0.049 13.1 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PIF1 PF05970.9 EXF75788.1 - 0.073 12.0 0.0 4.9 5.9 0.0 2.7 3 0 0 3 3 3 0 PIF1-like helicase ATP_bind_1 PF03029.12 EXF75788.1 - 0.085 12.3 0.1 1.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UvrD-helicase PF00580.16 EXF75788.1 - 0.094 11.9 3.5 0.21 10.8 0.1 2.2 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain V_ATPase_I PF01496.14 EXF75788.1 - 0.18 9.6 3.3 0.25 9.1 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family OmpH PF03938.9 EXF75788.1 - 0.29 11.0 6.4 0.67 9.8 4.4 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Seryl_tRNA_N PF02403.17 EXF75788.1 - 0.32 11.0 13.9 2.1 8.3 7.9 3.1 2 1 0 2 2 1 0 Seryl-tRNA synthetase N-terminal domain OEP PF02321.13 EXF75788.1 - 0.33 10.5 5.0 0.95 9.0 3.5 1.8 1 0 0 1 1 1 0 Outer membrane efflux protein IncA PF04156.9 EXF75788.1 - 0.75 9.3 13.4 0.56 9.7 8.0 1.7 2 0 0 2 2 1 0 IncA protein Mnd1 PF03962.10 EXF75788.1 - 1.1 8.8 10.7 2.2 7.9 7.4 1.4 1 0 0 1 1 1 0 Mnd1 family CR6_interact PF10147.4 EXF75788.1 - 1.1 8.4 9.7 2 7.6 6.7 1.3 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Atg14 PF10186.4 EXF75788.1 - 1.9 7.3 5.7 3.9 6.3 4.0 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EXF75788.1 - 3.4 6.6 8.6 6.2 5.7 6.0 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Ribosomal_L6e PF01159.14 EXF75789.1 - 4.5e-37 126.6 0.3 7.4e-37 125.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L6e Gmx_para_CXXCG PF09535.5 EXF75789.1 - 0.085 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) Peptidase_M49 PF03571.10 EXF75790.1 - 1.1e-230 766.4 0.0 1.3e-230 766.1 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 SKI PF01202.17 EXF75791.1 - 2.8e-12 46.8 0.0 3.5e-12 46.4 0.0 1.1 1 0 0 1 1 1 1 Shikimate kinase AAA_17 PF13207.1 EXF75791.1 - 2.8e-10 41.0 0.0 4e-10 40.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EXF75791.1 - 3.1e-10 40.0 0.0 4.1e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EXF75791.1 - 2.7e-08 34.1 0.0 6.2e-08 33.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.10 EXF75791.1 - 3.2e-05 22.8 0.0 4.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 EXF75791.1 - 5.3e-05 23.4 0.1 0.00015 21.9 0.0 1.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EXF75791.1 - 0.00013 22.1 0.0 0.00026 21.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EXF75791.1 - 0.00071 19.5 0.0 0.0019 18.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EXF75791.1 - 0.001 18.7 0.0 0.0024 17.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 EXF75791.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EXF75791.1 - 0.0015 18.5 0.0 0.0023 17.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain CoaE PF01121.15 EXF75791.1 - 0.0017 17.7 0.0 0.012 14.9 0.0 2.2 2 1 0 2 2 2 1 Dephospho-CoA kinase RNA_helicase PF00910.17 EXF75791.1 - 0.0023 18.0 0.0 0.0042 17.2 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.9 EXF75791.1 - 0.0026 17.4 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) PRK PF00485.13 EXF75791.1 - 0.0036 16.8 0.0 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_14 PF13173.1 EXF75791.1 - 0.0036 17.1 0.0 0.011 15.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EXF75791.1 - 0.004 16.5 0.0 1.6 8.0 0.0 2.1 2 0 0 2 2 2 1 Thymidylate kinase Cytidylate_kin2 PF13189.1 EXF75791.1 - 0.0044 16.9 0.1 0.039 13.8 0.0 2.1 1 1 0 2 2 2 1 Cytidylate kinase-like family ABC_tran PF00005.22 EXF75791.1 - 0.0096 16.2 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_30 PF13604.1 EXF75791.1 - 0.013 15.1 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EXF75791.1 - 0.026 13.7 0.0 0.059 12.5 0.0 1.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI APS_kinase PF01583.15 EXF75791.1 - 0.026 14.1 0.0 0.039 13.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase RuvB_N PF05496.7 EXF75791.1 - 0.052 12.5 0.1 0.15 11.1 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus NTPase_1 PF03266.10 EXF75791.1 - 0.062 13.0 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 NTPase MobB PF03205.9 EXF75791.1 - 0.065 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PhoH PF02562.11 EXF75791.1 - 0.068 12.3 0.1 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein Zeta_toxin PF06414.7 EXF75791.1 - 0.068 12.2 0.0 0.097 11.7 0.0 1.5 1 1 0 1 1 1 0 Zeta toxin T2SE PF00437.15 EXF75791.1 - 0.068 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Arch_ATPase PF01637.13 EXF75791.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase ADK PF00406.17 EXF75791.1 - 0.13 12.1 0.1 2.3 8.1 0.0 2.1 2 0 0 2 2 2 0 Adenylate kinase AAA_23 PF13476.1 EXF75791.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EXF75791.1 - 0.13 11.8 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EXF75791.1 - 0.14 11.2 0.1 0.75 8.8 0.0 1.9 2 0 0 2 2 2 0 KaiC DNA_pol3_delta2 PF13177.1 EXF75791.1 - 0.16 11.5 0.0 0.17 11.5 0.0 1.3 1 1 0 1 1 1 0 DNA polymerase III, delta subunit 2-oxoacid_dh PF00198.18 EXF75792.1 - 1.3e-73 247.1 0.1 3.6e-73 245.6 0.0 1.7 2 0 0 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EXF75792.1 - 3.1e-18 65.1 0.1 5.1e-18 64.4 0.0 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EXF75792.1 - 1.9e-12 46.5 0.0 5.5e-12 45.1 0.0 1.9 1 0 0 1 1 1 1 e3 binding domain BEX PF04538.7 EXF75792.1 - 0.037 14.2 2.4 0.12 12.5 0.0 2.2 2 0 0 2 2 2 0 Brain expressed X-linked like family Biotin_lipoyl_2 PF13533.1 EXF75792.1 - 0.084 12.5 0.1 0.66 9.6 0.0 2.3 2 0 0 2 2 2 0 Biotin-lipoyl like ATP-synt_10 PF05176.9 EXF75793.1 - 4.1e-82 275.2 0.0 5.1e-82 274.9 0.0 1.0 1 0 0 1 1 1 1 ATP10 protein V-SNARE_C PF12352.3 EXF75794.1 - 1.8e-12 47.1 0.8 1.8e-12 47.1 0.5 2.4 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus STAT_alpha PF01017.15 EXF75794.1 - 0.12 12.1 3.9 7.2 6.2 0.0 2.4 2 1 0 2 2 2 0 STAT protein, all-alpha domain IncA PF04156.9 EXF75794.1 - 9.8 5.7 10.5 4.7 6.7 4.9 1.8 1 1 0 2 2 2 0 IncA protein Ribosomal_L29 PF00831.18 EXF75795.1 - 2.9e-17 62.1 3.3 3.1e-17 62.0 0.5 2.0 2 0 0 2 2 2 1 Ribosomal L29 protein DUF2450 PF10475.4 EXF75795.1 - 0.098 11.5 1.0 0.12 11.2 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function N-terminal domain (DUF2450) zf-H2C2_2 PF13465.1 EXF75796.1 - 1.2e-23 82.1 34.1 5.1e-08 32.8 0.1 6.8 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 EXF75796.1 - 5.5e-12 45.2 51.5 0.00024 21.2 0.4 8.1 8 0 0 8 8 8 6 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF75796.1 - 1.2e-07 31.4 40.3 0.096 13.0 0.1 8.5 8 0 0 8 8 8 6 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EXF75796.1 - 0.012 15.5 0.1 0.012 15.5 0.1 4.9 5 0 0 5 5 5 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EXF75796.1 - 0.018 15.1 19.7 0.72 10.0 0.1 5.6 6 0 0 6 6 6 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EXF75796.1 - 0.39 10.9 20.3 1.1 9.5 0.2 6.4 6 0 0 6 6 6 0 Zinc-finger of C2H2 type AICARFT_IMPCHas PF01808.13 EXF75797.1 - 9.7e-111 369.8 0.0 1.2e-110 369.4 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EXF75797.1 - 1.5e-23 82.5 0.0 3.1e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 MGS-like domain Tir_receptor_N PF07490.6 EXF75798.1 - 0.084 12.4 3.0 0.11 12.1 2.1 1.1 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) N-terminus MRP-S31 PF15433.1 EXF75798.1 - 3.7 6.9 7.5 4.7 6.5 5.2 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF4407 PF14362.1 EXF75798.1 - 8.9 5.1 10.9 11 4.8 7.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DEAD PF00270.24 EXF75799.1 - 1.2e-44 151.7 0.0 4.1e-43 146.7 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF75799.1 - 5.5e-23 80.6 0.0 1.5e-22 79.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EXF75799.1 - 0.16 10.7 0.0 0.3 9.8 0.0 1.4 1 0 0 1 1 1 0 SNF2 family N-terminal domain HCNGP PF07818.8 EXF75800.1 - 4.3e-22 77.9 0.0 6.3e-22 77.4 0.0 1.3 1 0 0 1 1 1 1 HCNGP-like protein DUF3712 PF12505.3 EXF75801.1 - 3.4e-24 85.2 2.8 3.4e-24 85.2 1.9 2.1 3 0 0 3 3 3 1 Protein of unknown function (DUF3712) LRR19-TM PF15176.1 EXF75801.1 - 0.22 11.2 0.6 0.41 10.3 0.4 1.4 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain FMN_dh PF01070.13 EXF75802.1 - 1.2e-107 359.8 0.0 1.6e-107 359.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EXF75802.1 - 2e-21 75.5 0.0 5e-21 74.2 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EXF75802.1 - 1e-07 31.2 0.1 1.7e-07 30.5 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EXF75802.1 - 1.6e-05 23.9 0.1 0.00029 19.8 0.0 2.3 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EXF75802.1 - 0.011 15.0 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein DHO_dh PF01180.16 EXF75802.1 - 0.035 13.0 0.0 0.062 12.2 0.0 1.4 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase NMO PF03060.10 EXF75802.1 - 0.037 13.1 0.2 0.059 12.5 0.1 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Ribul_P_3_epim PF00834.14 EXF75802.1 - 0.13 11.3 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family HSCB_C PF07743.8 EXF75803.1 - 5.7e-15 55.5 4.9 7.3e-15 55.1 2.1 1.9 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EXF75803.1 - 6.4e-11 41.8 0.1 1.3e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain PCI PF01399.22 EXF75804.1 - 2e-10 40.9 0.0 6.1e-10 39.3 0.0 1.8 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.4 EXF75804.1 - 0.049 13.0 0.0 0.089 12.1 0.0 1.4 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_12 PF13424.1 EXF75804.1 - 0.065 13.1 0.7 0.46 10.4 0.0 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF3138 PF11336.3 EXF75804.1 - 0.15 10.2 1.3 0.23 9.6 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Lipase_GDSL_2 PF13472.1 EXF75805.1 - 9.8e-22 77.9 0.1 1.2e-21 77.6 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EXF75805.1 - 4.5e-09 36.4 0.6 3.2e-08 33.7 0.4 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Profilin PF00235.14 EXF75807.1 - 1.5e-36 125.1 0.8 1.7e-36 124.9 0.6 1.0 1 0 0 1 1 1 1 Profilin Got1 PF04178.7 EXF75808.1 - 9.4e-19 67.6 11.5 1.1e-18 67.4 8.0 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family YrhK PF14145.1 EXF75808.1 - 0.76 9.4 8.7 0.097 12.3 2.4 2.2 2 1 0 2 2 2 0 YrhK-like protein YL1_C PF08265.6 EXF75809.1 - 6e-16 57.6 0.1 9.4e-16 57.0 0.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain Gly-rich_Ago1 PF12764.2 EXF75809.1 - 1.3 9.6 8.2 1.7 9.3 0.7 2.8 1 1 1 2 2 2 0 Glycine-rich region of argonaut DASH_Dad4 PF08650.5 EXF75810.1 - 2.3e-28 97.9 6.0 2.5e-28 97.7 4.2 1.0 1 0 0 1 1 1 1 DASH complex subunit Dad4 DASH_Dad1 PF08649.5 EXF75810.1 - 0.032 13.9 3.3 0.04 13.6 2.3 1.2 1 0 0 1 1 1 0 DASH complex subunit Dad1 GM_CSF PF01109.12 EXF75810.1 - 0.059 13.3 0.5 0.068 13.1 0.3 1.1 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor Pecanex_C PF05041.10 EXF75810.1 - 0.078 12.0 0.2 0.087 11.8 0.1 1.0 1 0 0 1 1 1 0 Pecanex protein (C-terminus) Biotin_carb_C PF02785.14 EXF75810.1 - 0.14 12.1 0.0 0.15 12.0 0.0 1.1 1 0 0 1 1 1 0 Biotin carboxylase C-terminal domain Actin PF00022.14 EXF75811.1 - 8.5e-59 198.9 0.0 2.3e-35 121.7 0.0 2.2 2 0 0 2 2 2 2 Actin OmpH PF03938.9 EXF75811.1 - 0.00062 19.7 0.1 0.00062 19.7 0.1 2.5 2 0 0 2 2 2 1 Outer membrane protein (OmpH-like) bZIP_1 PF00170.16 EXF75812.1 - 4.9e-08 32.8 6.8 4.9e-08 32.8 4.7 1.7 2 0 0 2 2 2 1 bZIP transcription factor Leu_zip PF15294.1 EXF75812.1 - 0.046 12.8 0.9 0.071 12.2 0.6 1.2 1 0 0 1 1 1 0 Leucine zipper bZIP_2 PF07716.10 EXF75812.1 - 0.25 11.1 9.6 4.2 7.2 4.3 2.6 1 1 1 2 2 2 0 Basic region leucine zipper Amidohydro_1 PF01979.15 EXF75813.1 - 3.9e-31 108.9 0.0 5e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EXF75813.1 - 2.4e-15 57.2 1.4 3.6e-07 30.4 0.1 2.8 2 1 1 3 3 3 2 Amidohydrolase Amidohydro_3 PF07969.6 EXF75813.1 - 1.4e-05 24.5 1.4 1.4e-05 24.5 0.9 2.2 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 EXF75813.1 - 1.5e-05 24.7 0.1 3.9e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 Amidohydrolase DUF3606 PF12244.3 EXF75813.1 - 0.044 13.4 0.3 0.13 11.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) Pterin_4a PF01329.14 EXF75814.1 - 4.4e-28 96.8 0.1 6e-28 96.4 0.0 1.2 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Endotoxin_mid PF09131.5 EXF75814.1 - 0.048 13.1 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacillus thuringiensis delta-Endotoxin, middle domain FA_hydroxylase PF04116.8 EXF75815.1 - 1e-15 58.1 17.2 1e-15 58.1 11.9 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily FDC-SP PF15215.1 EXF75815.1 - 0.53 10.6 0.0 0.53 10.6 0.0 2.6 3 1 0 3 3 3 0 Follicular dendritic cell secreted peptide NCA2 PF08637.5 EXF75816.1 - 1.8e-89 299.5 0.0 2.6e-89 298.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 TMEM171 PF15471.1 EXF75816.1 - 0.15 10.8 0.1 0.25 10.1 0.1 1.2 1 0 0 1 1 1 0 Transmembrane protein family 171 Ras PF00071.17 EXF75817.1 - 1.6e-64 216.1 0.0 1.9e-64 215.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EXF75817.1 - 1.4e-19 70.7 0.0 1.9e-19 70.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EXF75817.1 - 3.7e-13 49.0 0.0 4.1e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EXF75817.1 - 2.5e-06 27.0 0.0 4.4e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EXF75817.1 - 8.1e-06 25.1 0.0 8.7e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EXF75817.1 - 0.0043 17.0 0.0 0.0063 16.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EXF75817.1 - 0.023 13.9 0.0 0.028 13.6 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EXF75817.1 - 0.049 12.9 0.0 0.23 10.7 0.0 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B DUF258 PF03193.11 EXF75817.1 - 0.081 12.1 0.0 0.19 10.8 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EXF75817.1 - 0.1 12.1 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EXF75817.1 - 0.11 12.6 0.0 0.27 11.3 0.0 1.9 1 1 1 2 2 2 0 AAA domain G-alpha PF00503.15 EXF75817.1 - 0.12 11.0 0.4 13 4.3 0.0 2.7 1 1 1 2 2 2 0 G-protein alpha subunit AAA PF00004.24 EXF75819.1 - 2.2e-53 179.9 0.0 2.2e-39 134.6 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EXF75819.1 - 2.7e-06 27.2 0.0 0.0099 15.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EXF75819.1 - 4.4e-06 26.8 1.1 0.031 14.2 0.3 3.6 2 2 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.9 EXF75819.1 - 6.3e-06 25.9 0.1 0.063 13.0 0.0 3.6 3 2 1 4 4 3 2 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EXF75819.1 - 1.1e-05 24.9 3.2 0.0075 15.6 0.0 3.7 2 2 2 4 4 4 1 AAA domain AAA_22 PF13401.1 EXF75819.1 - 5.6e-05 23.2 1.1 0.5 10.5 0.4 4.1 2 2 0 3 3 3 1 AAA domain AAA_28 PF13521.1 EXF75819.1 - 0.00024 21.0 0.0 0.021 14.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain Vps4_C PF09336.5 EXF75819.1 - 0.00041 20.1 0.0 0.055 13.3 0.0 2.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain CDC48_N PF02359.13 EXF75819.1 - 0.00049 19.9 0.0 0.0095 15.8 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_19 PF13245.1 EXF75819.1 - 0.00058 19.5 1.0 0.66 9.7 0.0 3.8 4 1 0 4 4 4 1 Part of AAA domain AAA_33 PF13671.1 EXF75819.1 - 0.0013 18.6 0.0 0.03 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EXF75819.1 - 0.005 16.9 0.0 4.2 7.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase RuvB_N PF05496.7 EXF75819.1 - 0.0077 15.3 0.0 0.03 13.3 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EXF75819.1 - 0.018 15.8 0.0 0.17 12.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.1 EXF75819.1 - 0.053 13.5 0.0 3.9 7.5 0.0 2.6 2 1 0 2 2 2 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EXF75819.1 - 0.061 12.7 0.3 8.5 5.7 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein DUF815 PF05673.8 EXF75819.1 - 0.076 11.9 0.1 0.28 10.0 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF815) Torsin PF06309.6 EXF75819.1 - 0.079 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Torsin NACHT PF05729.7 EXF75819.1 - 0.11 12.1 0.3 5.3 6.6 0.1 3.3 3 1 1 4 4 4 0 NACHT domain DUF2075 PF09848.4 EXF75819.1 - 0.21 10.4 0.6 3.9 6.3 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2075) SE PF08491.5 EXF75820.1 - 7.6e-86 287.3 0.0 9.8e-86 286.9 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase DAO PF01266.19 EXF75820.1 - 7.3e-10 38.2 1.5 2.7e-07 29.8 0.6 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EXF75820.1 - 1.4e-08 34.1 2.5 2.4e-06 26.8 0.3 2.5 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EXF75820.1 - 2.2e-05 24.4 0.5 4.9e-05 23.2 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EXF75820.1 - 3.8e-05 22.8 0.0 6.4e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EXF75820.1 - 9.3e-05 21.4 1.0 0.00022 20.1 0.7 1.6 1 1 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EXF75820.1 - 0.0014 18.9 0.8 0.02 15.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF75820.1 - 0.0019 17.0 0.3 0.0029 16.5 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EXF75820.1 - 0.0036 16.2 0.1 0.035 13.0 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Shikimate_DH PF01488.15 EXF75820.1 - 0.0041 17.2 0.0 0.0075 16.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_oxidored PF12831.2 EXF75820.1 - 0.0053 15.8 0.4 0.0099 15.0 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.11 EXF75820.1 - 0.0059 16.0 0.1 0.01 15.2 0.1 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 EXF75820.1 - 0.011 15.6 1.1 0.033 14.0 0.8 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EXF75820.1 - 0.013 15.1 0.1 0.023 14.3 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EXF75820.1 - 0.015 15.0 0.1 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HI0933_like PF03486.9 EXF75820.1 - 0.054 11.9 0.1 0.082 11.3 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein GDI PF00996.13 EXF75820.1 - 0.17 10.1 0.0 0.3 9.3 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Glycos_transf_2 PF00535.21 EXF75821.1 - 5.8e-25 87.9 0.0 1.2e-24 86.8 0.0 1.4 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EXF75821.1 - 1.5e-09 38.0 0.2 5.5e-07 29.6 0.1 3.0 2 1 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EXF75821.1 - 0.0012 18.0 0.0 0.0017 17.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.1 EXF75821.1 - 0.044 14.0 0.0 0.088 13.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 SMK-1 PF04802.10 EXF75824.1 - 1.2e-78 263.0 0.2 2e-78 262.3 0.1 1.3 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Chlam_vir PF05475.6 EXF75824.1 - 0.072 12.1 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Chlamydia virulence protein PGP3-D DUF713 PF05218.9 EXF75825.1 - 0.059 13.0 0.0 0.17 11.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF713) PPR_3 PF13812.1 EXF75825.1 - 0.093 13.0 2.6 10 6.6 0.0 4.7 4 0 0 4 4 4 0 Pentatricopeptide repeat domain Aldo_ket_red PF00248.16 EXF75826.1 - 1.9e-63 213.9 0.0 2.1e-63 213.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.27 EXF75829.1 - 2.8e-19 68.2 0.1 2.4e-05 24.0 0.0 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat EIF_2_alpha PF07541.7 EXF75830.1 - 2.2e-38 130.4 0.0 4.8e-38 129.3 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.18 EXF75830.1 - 2.1e-13 50.1 0.9 4.9e-13 48.9 0.6 1.7 1 0 0 1 1 1 1 S1 RNA binding domain HATPase_c PF02518.21 EXF75831.1 - 9.7e-25 86.4 0.1 2e-24 85.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EXF75831.1 - 1.9e-23 82.5 0.2 4.3e-22 78.2 0.0 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EXF75831.1 - 4.8e-21 74.5 0.3 2.2e-20 72.4 0.1 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 EXF75831.1 - 5.3e-21 74.5 1.4 6.1e-11 42.2 0.3 3.7 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.1 EXF75831.1 - 1.3e-15 57.6 0.0 6.6e-07 29.6 0.0 3.5 2 1 0 2 2 2 2 PAS domain PAS PF00989.19 EXF75831.1 - 7.4e-09 35.3 0.0 0.0052 16.5 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.5 EXF75831.1 - 1.5e-08 34.6 0.5 6.7e-05 22.8 0.1 3.3 4 0 0 4 4 4 2 PAS fold UPF0565 PF10561.4 EXF75831.1 - 0.046 12.5 0.0 0.079 11.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 Cpn60_TCP1 PF00118.19 EXF75833.1 - 4.2e-163 543.4 0.0 4.9e-163 543.2 0.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1168 PF06658.7 EXF75834.1 - 1.7e-41 141.0 15.0 2.7e-41 140.4 10.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) DNA_pol3_a_NII PF11490.3 EXF75834.1 - 2 8.0 8.0 4.3 6.9 5.5 1.4 1 0 0 1 1 1 0 DNA polymerase III polC-type N-terminus II His_Phos_1 PF00300.17 EXF75835.1 - 8.3e-32 110.4 1.0 1.3e-31 109.8 0.0 1.8 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.17 EXF75835.1 - 5.8e-05 22.5 0.0 9.4e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Nucleo_P87 PF07267.6 EXF75835.1 - 0.44 9.1 2.2 0.95 8.0 1.5 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Cwf_Cwc_15 PF04889.7 EXF75835.1 - 0.85 9.2 17.3 0.073 12.7 4.2 2.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Mito_carr PF00153.22 EXF75836.1 - 4.6e-60 199.3 0.0 1.7e-19 69.2 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein SPRY PF00622.23 EXF75837.1 - 2.1e-06 27.8 0.1 1.3e-05 25.3 0.0 2.3 3 0 0 3 3 3 1 SPRY domain SMC_Nse1 PF07574.8 EXF75839.1 - 7.4e-36 123.6 0.0 9.7e-36 123.2 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.6 EXF75839.1 - 2.3e-12 46.6 12.6 3.8e-12 46.0 8.7 1.3 1 0 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.1 EXF75839.1 - 0.42 10.4 8.4 0.77 9.6 5.8 1.5 1 0 0 1 1 1 0 Ring finger domain NB-ARC PF00931.17 EXF75842.1 - 6.7e-12 44.8 0.0 1.1e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.1 EXF75842.1 - 8.1e-12 44.9 6.7 0.00011 22.0 0.3 4.5 2 1 3 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.12 EXF75842.1 - 2.9e-07 29.9 9.2 0.3 11.1 0.1 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 EXF75842.1 - 8.9e-06 25.2 4.7 0.0048 16.5 0.3 4.6 3 2 2 5 5 5 2 TPR repeat TPR_16 PF13432.1 EXF75842.1 - 0.00014 22.4 5.9 0.011 16.3 0.1 4.2 4 1 1 5 5 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EXF75842.1 - 0.00031 20.2 5.3 0.89 9.2 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat AAA_16 PF13191.1 EXF75842.1 - 0.00037 20.5 0.0 0.0011 19.0 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain Apc3 PF12895.2 EXF75842.1 - 0.00081 19.4 4.1 0.084 13.0 0.4 3.5 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 AAA_22 PF13401.1 EXF75842.1 - 0.00093 19.3 0.0 0.0025 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain SPO22 PF08631.5 EXF75842.1 - 0.024 13.7 0.1 0.053 12.5 0.1 1.6 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like TPR_7 PF13176.1 EXF75842.1 - 0.034 13.9 1.5 34 4.5 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Arch_ATPase PF01637.13 EXF75842.1 - 0.047 13.3 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase TPR_8 PF13181.1 EXF75842.1 - 0.048 13.4 1.2 71 3.5 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.1 EXF75842.1 - 0.44 10.5 4.1 8.7 6.4 0.0 4.3 6 0 0 6 6 5 0 Tetratricopeptide repeat Clr2 PF10383.4 EXF75843.1 - 4.4e-10 39.6 0.0 1.6e-08 34.6 0.0 2.5 2 0 0 2 2 2 1 Transcription-silencing protein Clr2 Glyco_hydro_43 PF04616.9 EXF75844.1 - 6.8e-33 113.9 4.4 2.4e-31 108.8 3.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolases family 43 VHL PF01847.11 EXF75844.1 - 0.16 11.5 0.1 2.4 7.6 0.0 2.1 2 0 0 2 2 2 0 von Hippel-Lindau disease tumour suppressor protein DUF2052 PF09747.4 EXF75845.1 - 5.5e-33 114.4 13.6 2.6e-30 105.6 9.4 2.1 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) Response_reg PF00072.19 EXF75846.1 - 1.2e-20 73.5 0.0 9.9e-14 51.3 0.0 2.5 2 0 0 2 2 2 2 Response regulator receiver domain Bot1p PF12298.3 EXF75847.1 - 2e-49 167.8 6.3 2.9e-49 167.2 4.4 1.3 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein GAGA_bind PF06217.7 EXF75847.1 - 0.17 11.8 1.1 0.25 11.2 0.8 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family Y_phosphatase3 PF13350.1 EXF75848.1 - 2.4e-46 157.9 0.0 3.7e-46 157.3 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EXF75848.1 - 1.6e-14 53.7 0.0 3.4e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EXF75848.1 - 0.00033 20.0 0.0 0.00049 19.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EXF75848.1 - 0.0035 16.7 0.0 0.0059 15.9 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EXF75848.1 - 0.021 14.8 0.0 0.033 14.2 0.0 1.4 1 0 0 1 1 1 0 Inositol hexakisphosphate APH PF01636.18 EXF75848.1 - 0.032 13.9 0.3 2.1 8.0 0.0 2.5 2 1 0 2 2 2 0 Phosphotransferase enzyme family DSPc PF00782.15 EXF75848.1 - 0.075 12.6 0.0 0.47 10.0 0.0 2.1 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain MARVEL PF01284.18 EXF75850.1 - 0.00079 19.2 13.0 0.00079 19.2 9.0 2.1 1 1 1 2 2 2 2 Membrane-associating domain VIT1 PF01988.14 EXF75850.1 - 1 8.7 7.3 0.31 10.4 3.2 1.5 1 1 0 1 1 1 0 VIT family DUF4349 PF14257.1 EXF75850.1 - 7.1 5.7 8.5 20 4.3 2.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) ALIX_LYPXL_bnd PF13949.1 EXF75851.1 - 0.03 13.2 0.1 0.044 12.7 0.0 1.1 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV BAR PF03114.13 EXF75852.1 - 5.6e-12 45.6 0.0 8e-12 45.1 0.0 1.2 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 EXF75852.1 - 5.9e-11 41.7 1.6 6.6e-11 41.6 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EXF75852.1 - 1.8e-10 40.0 0.3 4.3e-10 38.8 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EXF75852.1 - 4e-09 35.8 0.1 8.5e-09 34.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Hydantoinase_A PF01968.13 EXF75852.1 - 0.38 9.8 1.3 1.3 8.0 0.2 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase DUF566 PF04484.7 EXF75852.1 - 0.47 9.9 3.3 0.86 9.0 2.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF2439 PF10382.4 EXF75853.1 - 4e-26 91.0 0.1 6.8e-26 90.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) Zn_clus PF00172.13 EXF75854.1 - 0.22 11.4 9.6 0.49 10.3 6.6 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain dCMP_cyt_deam_1 PF00383.17 EXF75855.1 - 1.7e-21 75.7 0.0 4.7e-21 74.3 0.0 1.7 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EXF75855.1 - 8.4e-05 22.4 0.4 0.0056 16.5 0.0 2.5 2 0 0 2 2 2 1 Bd3614-like deaminase DUF3275 PF11679.3 EXF75855.1 - 2 8.0 0.0 2 8.0 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF3275) Xan_ur_permease PF00860.15 EXF75856.1 - 3.7e-27 94.8 33.6 5.7e-27 94.2 20.3 2.5 2 1 0 2 2 2 1 Permease family Na_H_Exchanger PF00999.16 EXF75859.1 - 3.8e-69 233.0 47.9 5.5e-69 232.5 33.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family A_deaminase PF00962.17 EXF75861.1 - 9.1e-68 228.6 0.0 1e-67 228.4 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase TRM PF02005.11 EXF75861.1 - 0.042 12.7 0.0 0.057 12.3 0.0 1.1 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Abhydrolase_3 PF07859.8 EXF75862.1 - 4.4e-35 121.1 0.0 3.5e-25 88.8 0.0 2.6 3 0 0 3 3 3 2 alpha/beta hydrolase fold Lipase_3 PF01764.20 EXF75862.1 - 0.08 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) DUF2424 PF10340.4 EXF75862.1 - 0.16 10.5 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) HET PF06985.6 EXF75864.1 - 7.3e-34 116.9 0.6 1.2e-33 116.1 0.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3176 PF11374.3 EXF75865.1 - 0.11 12.3 0.4 11 5.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3176) Glyco_hydro_cc PF11790.3 EXF75866.1 - 2.1e-47 161.5 2.6 2.6e-47 161.2 1.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Aminotran_3 PF00202.16 EXF75867.1 - 9e-98 327.2 0.0 1.2e-97 326.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EXF75867.1 - 3.6e-05 22.8 0.0 0.0001 21.4 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II SnoaL_2 PF12680.2 EXF75868.1 - 0.024 15.0 0.0 0.086 13.2 0.0 1.8 2 0 0 2 2 2 0 SnoaL-like domain CaMKII_AD PF08332.5 EXF75868.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II Association Cutinase PF01083.17 EXF75869.1 - 4.9e-48 163.2 4.2 5.9e-48 162.9 2.9 1.1 1 0 0 1 1 1 1 Cutinase DUF2974 PF11187.3 EXF75869.1 - 0.022 14.1 0.1 0.037 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) TPIP1 PF15338.1 EXF75869.1 - 0.051 13.4 0.9 0.1 12.4 0.1 1.8 1 1 1 2 2 2 0 p53-regulated apoptosis-inducing protein 1 Abhydrolase_2 PF02230.11 EXF75869.1 - 0.065 12.6 0.1 0.09 12.2 0.1 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AIRC PF00731.15 EXF75869.1 - 1.3 8.3 5.9 16 4.7 0.0 2.6 1 1 1 2 2 2 0 AIR carboxylase ATG27 PF09451.5 EXF75871.1 - 2.6e-77 259.6 0.0 3.1e-77 259.4 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 CIMR PF00878.13 EXF75871.1 - 0.069 12.9 0.1 31 4.3 0.0 2.9 3 0 0 3 3 3 0 Cation-independent mannose-6-phosphate receptor repeat ESR1_C PF12743.2 EXF75872.1 - 0.031 13.8 0.5 0.071 12.6 0.4 1.6 1 0 0 1 1 1 0 Oestrogen-type nuclear receptor final C-terminal Hexapep PF00132.19 EXF75873.1 - 2.4e-08 33.1 0.3 7.2e-05 22.1 0.1 2.6 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EXF75873.1 - 0.00035 20.6 0.0 0.00088 19.3 0.0 1.7 1 1 0 1 1 1 1 MobA-like NTP transferase domain NTP_transferase PF00483.18 EXF75873.1 - 0.0041 16.4 0.0 0.0078 15.5 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 EXF75873.1 - 0.25 10.9 7.4 0.22 11.1 0.2 3.3 2 2 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Anophelin PF10731.4 EXF75873.1 - 2.3 8.3 5.6 5.8 7.0 3.9 1.6 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito zf-C2H2 PF00096.21 EXF75874.1 - 0.00012 22.1 14.0 0.00086 19.5 2.8 3.9 2 1 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF75874.1 - 0.0014 18.8 3.3 0.0014 18.8 2.3 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger YdjO PF14169.1 EXF75874.1 - 0.049 13.0 0.1 6.1 6.3 0.0 2.8 2 0 0 2 2 2 0 Cold-inducible protein YdjO LRR_6 PF13516.1 EXF75875.1 - 0.0017 18.2 0.3 2.7 8.3 0.0 4.1 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.28 EXF75875.1 - 0.1 12.6 0.3 1.7e+02 2.8 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 EXF75875.1 - 0.37 11.1 5.6 28 5.5 0.0 5.5 7 0 0 7 7 7 0 Leucine rich repeat Glyco_hydro_12 PF01670.11 EXF75876.1 - 7.7e-34 116.7 0.5 7.7e-34 116.7 0.4 1.7 1 1 1 2 2 2 1 Glycosyl hydrolase family 12 Phage_holin_5 PF06946.6 EXF75876.1 - 0.019 15.0 3.8 0.13 12.4 1.3 2.4 2 1 0 2 2 2 0 Phage holin PPV_E2_C PF00511.12 EXF75876.1 - 6.5 6.7 8.3 13 5.8 2.0 2.5 1 1 1 2 2 2 0 E2 (early) protein, C terminal Fungal_trans PF04082.13 EXF75877.1 - 9e-14 50.9 0.0 1.6e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ketoacyl-synt PF00109.21 EXF75878.1 - 3.1e-69 233.2 0.0 5.6e-69 232.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 EXF75878.1 - 2.6e-68 230.3 0.0 3.5e-67 226.6 0.0 2.3 2 0 0 2 2 2 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 EXF75878.1 - 8.2e-60 202.7 0.3 2.6e-59 201.1 0.1 2.0 2 0 0 2 2 2 1 Acyl transferase domain KR PF08659.5 EXF75878.1 - 1.8e-57 193.9 0.1 8.3e-57 191.7 0.0 2.3 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EXF75878.1 - 1.5e-47 161.6 0.1 8.9e-47 159.1 0.1 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EXF75878.1 - 9.9e-30 102.8 0.1 2.5e-29 101.5 0.1 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EXF75878.1 - 0.00063 18.8 0.4 0.0013 17.7 0.3 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.7 EXF75878.1 - 0.0043 16.8 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III PF08545.5 EXF75878.1 - 0.015 14.9 0.8 0.055 13.1 0.6 2.0 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PP-binding PF00550.20 EXF75878.1 - 0.09 13.0 0.1 0.24 11.6 0.1 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site MFS_1 PF07690.11 EXF75879.1 - 1.2e-36 126.1 50.0 1.2e-36 126.1 34.7 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF75879.1 - 7.4e-08 31.3 11.3 7.4e-08 31.3 7.8 3.7 2 1 1 3 3 3 1 Sugar (and other) transporter Myco_arth_vir_N PF09610.5 EXF75879.1 - 0.12 12.3 1.4 0.54 10.2 0.9 2.2 1 0 0 1 1 1 0 Mycoplasma virulence signal region (Myco_arth_vir_N) FAD_binding_3 PF01494.14 EXF75880.1 - 9.5e-26 90.6 0.1 1.9e-25 89.6 0.1 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF75880.1 - 1.4e-07 30.8 2.7 0.00035 19.5 0.6 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF75880.1 - 2.1e-05 23.6 0.7 0.011 14.7 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 EXF75880.1 - 8e-05 22.5 0.1 0.00022 21.1 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EXF75880.1 - 0.00026 19.9 0.1 0.00035 19.5 0.1 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EXF75880.1 - 0.00065 19.5 0.4 0.64 9.7 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EXF75880.1 - 0.045 13.8 0.2 0.12 12.4 0.1 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF75880.1 - 0.18 11.6 0.6 0.45 10.3 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF2834 PF11196.3 EXF75881.1 - 0.003 17.6 0.6 0.003 17.6 0.4 3.0 4 0 0 4 4 4 1 Protein of unknown function (DUF2834) DUF1270 PF06900.6 EXF75881.1 - 0.23 11.6 0.2 0.23 11.6 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1270) PhzC-PhzF PF02567.11 EXF75882.1 - 7e-39 133.7 0.3 2.4e-38 131.9 0.2 1.7 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein Amidohydro_3 PF07969.6 EXF75883.1 - 1.8e-14 53.8 0.0 2.1e-14 53.5 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EXF75883.1 - 6.5e-05 22.6 0.0 0.00015 21.5 0.0 1.7 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 EXF75883.1 - 0.013 15.5 0.1 0.031 14.3 0.1 1.8 1 1 0 1 1 1 0 Amidohydrolase Fungal_trans_2 PF11951.3 EXF75885.1 - 0.082 11.4 0.1 0.26 9.8 0.1 1.6 1 1 1 2 2 2 0 Fungal specific transcription factor domain SnoaL PF07366.7 EXF75886.1 - 2e-05 24.1 0.0 3.9e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EXF75886.1 - 5.8e-05 23.4 0.0 0.00045 20.5 0.0 2.3 2 0 0 2 2 2 1 SnoaL-like domain Fungal_trans_2 PF11951.3 EXF75887.1 - 1.3e-24 86.5 0.0 1.7e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF75887.1 - 2.1e-08 33.9 11.1 5.7e-08 32.5 7.7 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Opy2 PF09463.5 EXF75887.1 - 8 6.6 13.0 0.72 9.9 5.3 2.1 2 0 0 2 2 2 0 Opy2 protein Cu_amine_oxid PF01179.15 EXF75888.1 - 3.5e-163 543.1 0.0 4.3e-163 542.8 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EXF75888.1 - 2.6e-20 72.3 0.1 8.1e-20 70.7 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EXF75888.1 - 1.4e-14 53.9 0.0 2.9e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain AA_permease_2 PF13520.1 EXF75889.1 - 5.6e-51 173.4 51.9 7.1e-51 173.0 36.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF75889.1 - 4.5e-22 78.0 43.5 5.9e-22 77.6 30.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3493 PF11998.3 EXF75889.1 - 0.67 9.8 0.0 0.67 9.8 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3493) Aldedh PF00171.17 EXF75890.1 - 1.4e-183 610.4 0.0 1.6e-183 610.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Endonuc_subdom PF09062.5 EXF75890.1 - 0.16 12.7 0.1 0.45 11.2 0.0 1.7 2 0 0 2 2 2 0 PI-PfuI Endonuclease subdomain AMP-binding PF00501.23 EXF75891.1 - 3.3e-55 187.1 0.0 4.6e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Thioesterase PF00975.15 EXF75891.1 - 1.5e-30 107.1 0.0 6e-30 105.1 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 EXF75891.1 - 4.8e-09 36.3 0.8 1.4e-08 34.8 0.1 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Amdo_NSP PF12475.3 EXF75891.1 - 0.05 13.5 0.1 3.6 7.5 0.0 2.6 2 0 0 2 2 2 0 Amdovirus non-structural protein Fer4_NifH PF00142.13 EXF75892.1 - 0.052 12.7 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family p450 PF00067.17 EXF75893.1 - 2.2e-64 217.6 0.0 2.8e-64 217.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3931 PF13082.1 EXF75893.1 - 0.19 11.5 0.1 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3931) DAO PF01266.19 EXF75894.1 - 6.8e-34 117.3 0.0 8.3e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EXF75894.1 - 1.7e-07 30.2 0.2 5.8e-06 25.1 0.2 2.4 1 1 0 1 1 1 1 Tryptophan halogenase NAD_binding_9 PF13454.1 EXF75894.1 - 8.8e-05 22.3 0.0 0.02 14.6 0.0 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EXF75894.1 - 0.00043 20.2 0.0 0.11 12.3 0.0 2.6 1 1 2 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF75894.1 - 0.0044 17.0 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EXF75894.1 - 0.0064 16.5 0.0 0.48 10.4 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF75894.1 - 0.011 14.6 0.0 0.13 11.1 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A GMC_oxred_N PF00732.14 EXF75894.1 - 0.016 14.3 0.0 4 6.5 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase Shikimate_DH PF01488.15 EXF75894.1 - 0.04 14.0 0.0 0.08 13.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EXF75894.1 - 0.058 13.8 0.0 1.3 9.4 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EXF75894.1 - 0.078 13.2 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding TrkA_N PF02254.13 EXF75894.1 - 0.13 12.2 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 EXF75894.1 - 0.17 11.2 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF3638 PF12340.3 EXF75898.1 - 2.6e-107 357.0 0.6 5.1e-107 356.0 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.3 EXF75898.1 - 1e-15 56.5 0.0 2.5e-15 55.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) MFS_1 PF07690.11 EXF75899.1 - 1.6e-14 53.4 20.8 1.6e-14 53.4 14.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EXF75899.1 - 3.6e-14 52.5 2.0 3.6e-14 52.5 1.4 2.9 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 OATP PF03137.15 EXF75899.1 - 0.063 11.3 8.3 0.82 7.6 1.1 2.8 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Ring_hydroxyl_A PF00848.14 EXF75900.1 - 1.4e-35 122.8 5.0 4e-35 121.3 3.5 1.7 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 EXF75900.1 - 2.2e-18 65.5 0.0 4.5e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CorC_HlyC PF03471.12 EXF75900.1 - 0.095 12.4 0.0 0.37 10.6 0.0 1.9 2 0 0 2 2 2 0 Transporter associated domain DAO PF01266.19 EXF75901.1 - 4.7e-42 144.1 0.0 9.5e-42 143.1 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EXF75901.1 - 1.1e-05 25.6 0.1 0.00024 21.2 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF75901.1 - 0.00011 22.0 0.0 0.42 10.4 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF75901.1 - 0.00013 21.7 0.0 0.0076 16.0 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EXF75901.1 - 0.00053 19.9 0.0 0.0018 18.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EXF75901.1 - 0.023 13.3 0.0 3.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase GIDA PF01134.17 EXF75901.1 - 0.037 12.9 0.0 0.12 11.2 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EXF75901.1 - 0.041 12.8 0.0 0.086 11.7 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 EXF75901.1 - 0.074 13.3 0.0 0.13 12.5 0.0 1.5 1 1 0 1 1 1 0 Putative NAD(P)-binding Fungal_trans PF04082.13 EXF75902.1 - 7.6e-10 38.0 0.5 1.3e-09 37.3 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DAO PF01266.19 EXF75903.1 - 8.6e-66 222.2 0.8 1.3e-65 221.6 0.6 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GCV_T PF01571.16 EXF75903.1 - 9.1e-51 172.2 0.0 2.3e-50 170.8 0.0 1.7 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EXF75903.1 - 2.3e-14 53.1 0.1 6.6e-14 51.7 0.0 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Pyr_redox_3 PF13738.1 EXF75903.1 - 4.4e-07 30.1 0.0 1.7e-06 28.2 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF75903.1 - 7.4e-05 23.0 0.9 0.046 14.1 0.1 2.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF75903.1 - 0.00064 18.6 0.3 0.0013 17.7 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EXF75903.1 - 0.0007 18.3 0.8 0.01 14.4 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase ThiF PF00899.16 EXF75903.1 - 0.00088 19.1 0.1 0.003 17.3 0.0 2.0 2 0 0 2 2 2 1 ThiF family NAD_binding_9 PF13454.1 EXF75903.1 - 0.0011 18.7 0.7 0.097 12.4 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding TrkA_N PF02254.13 EXF75903.1 - 0.003 17.5 0.1 0.011 15.6 0.1 2.0 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.15 EXF75903.1 - 0.017 15.2 0.0 0.04 14.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 EXF75903.1 - 0.017 13.6 0.2 0.056 11.9 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.14 EXF75903.1 - 0.017 14.2 1.2 0.13 11.3 0.8 2.0 1 1 0 1 1 1 0 FAD binding domain NAD_binding_8 PF13450.1 EXF75903.1 - 0.033 14.2 0.0 0.12 12.4 0.0 2.0 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF75903.1 - 0.036 13.9 1.0 0.33 10.8 0.4 2.6 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF75903.1 - 0.19 10.5 0.6 1.2 8.0 0.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein HSP70 PF00012.15 EXF75904.1 - 5.7e-07 27.8 0.2 0.00017 19.6 0.0 2.1 2 0 0 2 2 2 2 Hsp70 protein DDR PF08841.5 EXF75904.1 - 0.0096 14.7 0.1 0.014 14.2 0.1 1.2 1 0 0 1 1 1 1 Diol dehydratase reactivase ATPase-like domain MreB_Mbl PF06723.8 EXF75904.1 - 0.02 13.5 0.1 0.033 12.8 0.1 1.3 1 0 0 1 1 1 0 MreB/Mbl protein DUF3552 PF12072.3 EXF75905.1 - 0.039 13.1 2.9 0.065 12.4 2.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) ADH_zinc_N PF00107.21 EXF75906.1 - 6.5e-16 58.0 0.0 1.6e-15 56.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF75906.1 - 2.3e-07 30.5 0.4 9.6e-07 28.5 0.2 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EXF75906.1 - 0.025 15.4 0.0 0.053 14.4 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase NmrA PF05368.8 EXF75907.1 - 8.2e-20 71.0 0.1 9.7e-20 70.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF75907.1 - 1.8e-13 50.8 0.0 2.9e-13 50.2 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EXF75907.1 - 2.7e-06 26.6 0.0 4.9e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EXF75907.1 - 0.098 12.0 0.0 0.59 9.5 0.0 2.2 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EXF75908.1 - 1.1e-34 119.7 0.0 4.8e-34 117.6 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF75908.1 - 1.4e-11 44.7 0.1 1.9e-11 44.2 0.1 1.1 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EXF75908.1 - 1.2e-05 25.2 0.1 2e-05 24.5 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 EXF75908.1 - 0.0007 18.3 0.0 0.00089 18.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EXF75908.1 - 0.002 17.1 0.1 0.0033 16.4 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 EXF75908.1 - 0.0082 16.0 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EXF75908.1 - 0.017 14.5 0.0 0.028 13.8 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family FAD_binding_3 PF01494.14 EXF75909.1 - 6.8e-10 38.5 0.1 2e-09 36.9 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EXF75909.1 - 0.001 19.0 0.1 0.003 17.5 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF75909.1 - 0.0072 15.2 0.1 0.015 14.2 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_10 PF13460.1 EXF75910.1 - 2.5e-11 43.9 0.1 4.3e-11 43.1 0.1 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EXF75910.1 - 5.5e-09 35.6 0.0 9.2e-09 34.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EXF75910.1 - 0.015 14.7 0.1 0.056 12.8 0.0 2.0 3 1 0 3 3 3 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.13 EXF75912.1 - 1.5e-06 28.0 9.4 1.5e-06 28.0 6.5 2.2 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF75912.1 - 0.00024 20.0 0.1 0.00047 19.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 EXF75913.1 - 1.6e-19 69.8 0.5 2.7e-11 42.6 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Aa_trans PF01490.13 EXF75915.1 - 1.3e-53 182.0 42.0 1.4e-53 181.8 29.1 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein ATG27 PF09451.5 EXF75915.1 - 0.54 9.4 1.4 1.2 8.3 1.0 1.5 1 0 0 1 1 1 0 Autophagy-related protein 27 Anticodon_1 PF08264.8 EXF75918.1 - 0.096 12.4 0.0 0.24 11.1 0.0 1.8 1 0 0 1 1 1 0 Anticodon-binding domain of tRNA Fungal_trans PF04082.13 EXF75919.1 - 3.2e-18 65.5 0.0 6.2e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain FG-GAP PF01839.18 EXF75920.1 - 5.2e-05 22.8 4.2 0.16 11.6 0.4 2.7 2 0 0 2 2 2 2 FG-GAP repeat VCBS PF13517.1 EXF75920.1 - 0.00027 21.2 5.7 0.79 10.1 0.0 4.2 3 1 1 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Glyco_hydro_31 PF01055.21 EXF75921.1 - 1.3e-101 340.5 3.8 6.5e-101 338.3 2.7 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 RPE65 PF03055.10 EXF75922.1 - 5.7e-107 358.2 0.0 7e-107 357.9 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Tyrosinase PF00264.15 EXF75923.1 - 1.4e-53 182.3 1.7 1.9e-53 181.9 1.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DiS_P_DiS PF06750.8 EXF75923.1 - 0.0018 18.0 0.0 0.0054 16.4 0.0 1.7 2 0 0 2 2 2 1 Bacterial Peptidase A24 N-terminal domain PPO1_DWL PF12142.3 EXF75923.1 - 0.091 12.2 0.0 0.49 9.9 0.0 2.1 2 0 0 2 2 2 0 Polyphenol oxidase middle domain Metallophos PF00149.23 EXF75924.1 - 1.2e-09 37.8 0.0 2.1e-07 30.5 0.0 2.3 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EXF75924.1 - 2e-07 30.9 0.0 3.4e-07 30.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Fungal_trans PF04082.13 EXF75925.1 - 1.9e-36 125.3 0.0 3.6e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF75925.1 - 0.00013 21.7 1.2 0.00027 20.7 0.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4226 PF10774.4 EXF75925.1 - 0.16 12.0 2.7 0.21 11.6 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) HORMA PF02301.13 EXF75926.1 - 5.7e-46 156.6 0.0 7.2e-46 156.2 0.0 1.1 1 0 0 1 1 1 1 HORMA domain Stirrup PF09061.1 EXF75926.1 - 0.053 13.4 0.0 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 Stirrup UCH PF00443.24 EXF75927.1 - 2.6e-43 148.0 0.0 5.4e-43 147.0 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EXF75927.1 - 3.4e-23 80.7 0.5 2.9e-10 39.6 0.0 2.7 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.14 EXF75927.1 - 4.6e-22 77.8 14.6 3.2e-19 68.7 1.7 3.0 3 0 0 3 3 3 2 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EXF75927.1 - 8.7e-19 68.0 0.0 3.6e-17 62.7 0.0 2.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA_4 PF14555.1 EXF75927.1 - 0.07 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain UBA_3 PF09288.5 EXF75927.1 - 0.085 12.4 0.0 1 9.0 0.0 2.7 3 0 0 3 3 3 0 Fungal ubiquitin-associated domain CUE PF02845.11 EXF75927.1 - 0.1 12.0 0.0 0.94 9.0 0.0 2.4 2 0 0 2 2 2 0 CUE domain NifU_N PF01592.11 EXF75928.1 - 1.5e-50 170.3 0.0 2e-50 169.9 0.0 1.2 1 0 0 1 1 1 1 NifU-like N terminal domain adh_short PF00106.20 EXF75929.1 - 4.5e-14 52.7 1.6 9.6e-14 51.6 1.1 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF75929.1 - 2.6e-09 36.9 0.5 1.2e-08 34.8 0.3 2.0 2 1 0 2 2 2 1 KR domain Epimerase PF01370.16 EXF75929.1 - 0.0036 16.7 0.0 0.0055 16.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF75929.1 - 0.0074 16.3 0.5 0.022 14.7 0.3 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short_C2 PF13561.1 EXF75929.1 - 0.12 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EXF75929.1 - 0.15 10.9 0.0 0.2 10.5 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SieB PF14163.1 EXF75930.1 - 0.55 9.7 3.2 0.82 9.2 0.2 2.4 2 0 0 2 2 2 0 Superinfection exclusion protein B FixQ PF05545.6 EXF75930.1 - 0.87 9.2 11.9 2.5 7.8 0.0 3.8 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DEAD PF00270.24 EXF75931.1 - 3.4e-48 163.3 0.0 2.2e-46 157.4 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF75931.1 - 3.3e-29 100.5 0.1 2.5e-27 94.5 0.1 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.9 EXF75931.1 - 1.9e-05 24.0 4.4 4.2e-05 22.9 2.4 2.1 1 1 0 2 2 2 1 SecA DEAD-like domain SNF2_N PF00176.18 EXF75931.1 - 0.0002 20.2 0.0 0.00038 19.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Spore_coat_CotO PF14153.1 EXF75931.1 - 0.0071 15.8 14.1 0.012 15.0 9.7 1.4 1 0 0 1 1 1 1 Spore coat protein CotO DUF1253 PF06862.7 EXF75931.1 - 0.03 12.7 0.0 0.03 12.7 0.0 2.6 3 1 1 4 4 2 0 Protein of unknown function (DUF1253) CMS1 PF14617.1 EXF75931.1 - 0.21 10.6 0.0 0.21 10.6 0.0 3.4 2 1 1 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit Ycf1 PF05758.7 EXF75931.1 - 0.31 8.7 11.9 0.47 8.0 8.2 1.2 1 0 0 1 1 1 0 Ycf1 Neur_chan_memb PF02932.11 EXF75931.1 - 1.6 8.5 6.7 2 8.2 3.7 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region SAPS PF04499.10 EXF75931.1 - 3.4 6.1 10.2 4.7 5.7 7.1 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Seryl_tRNA_N PF02403.17 EXF75931.1 - 3.8 7.5 22.4 8.9 6.3 15.5 1.7 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Rft-1 PF04506.8 EXF75932.1 - 1.2e-89 301.1 5.9 1.6e-89 300.7 4.1 1.0 1 0 0 1 1 1 1 Rft protein DUF485 PF04341.7 EXF75932.1 - 3.2 7.5 11.8 2 8.1 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Tropomyosin_1 PF12718.2 EXF75933.1 - 1.7 8.4 31.0 0.54 10.0 17.4 2.7 1 1 1 2 2 2 0 Tropomyosin like DivIVA PF05103.8 EXF75933.1 - 2.1 8.3 29.1 1.3 9.0 0.8 3.8 2 1 2 4 4 4 0 DivIVA protein Ribosomal_L18e PF00828.14 EXF75937.1 - 2.2e-24 86.2 0.0 2.2e-24 86.2 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L18e/L15 Mito_carr PF00153.22 EXF75938.1 - 1.4e-73 242.7 4.3 3.4e-25 87.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 EXF75939.1 - 6.8e-12 44.8 0.0 9.6e-12 44.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF75939.1 - 4.9e-08 32.8 0.0 7.7e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF75939.1 - 6e-07 29.2 0.0 8.5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EXF75939.1 - 0.00037 20.1 0.0 0.00073 19.2 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif MIP-T3 PF10243.4 EXF75939.1 - 4.5 5.6 12.0 5.2 5.4 8.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 MBOAT PF03062.14 EXF75940.1 - 4.2e-41 141.1 12.3 4.2e-41 141.1 8.5 2.1 2 1 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EXF75940.1 - 1.6e-06 28.0 5.5 3.7e-06 26.9 3.8 1.6 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family CH PF00307.26 EXF75941.1 - 7.3e-57 190.0 0.0 3.2e-16 59.3 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_7 PF13499.1 EXF75941.1 - 7.7e-07 29.1 0.2 1.6e-05 24.8 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EXF75941.1 - 3.2e-05 22.9 0.7 1.4 8.3 0.0 3.6 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EXF75941.1 - 0.11 12.4 0.3 4 7.5 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain Ank_2 PF12796.2 EXF75942.1 - 0.00056 20.2 0.0 0.0013 19.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EXF75942.1 - 0.028 14.2 0.0 0.23 11.3 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat zf-RING_2 PF13639.1 EXF75942.1 - 0.031 14.1 9.0 0.074 12.8 6.3 1.8 1 1 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.1 EXF75942.1 - 0.041 13.7 3.1 0.089 12.6 2.1 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-CSL PF05207.8 EXF75942.1 - 1.9 8.0 4.6 1.3 8.6 2.0 1.6 1 1 0 1 1 1 0 CSL zinc finger DDHD PF02862.12 EXF75943.1 - 3.3e-75 252.7 0.0 3.3e-75 252.7 0.0 3.0 3 0 0 3 3 3 1 DDHD domain DUF2305 PF10230.4 EXF75943.1 - 0.094 12.1 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF1525 PF07511.6 EXF75943.1 - 0.28 11.1 2.1 0.77 9.7 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) RNA_pol_Rpb1_5 PF04998.12 EXF75944.1 - 4.4e-86 288.5 0.1 7.2e-86 287.8 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EXF75944.1 - 2.6e-85 286.6 0.0 4.1e-85 286.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EXF75944.1 - 1.4e-67 226.8 0.0 2.9e-67 225.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EXF75944.1 - 1.7e-40 138.3 0.0 4.4e-40 136.9 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EXF75944.1 - 1.4e-29 101.9 0.1 4.5e-29 100.3 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 Tannase PF07519.6 EXF75945.1 - 2.1e-102 343.3 1.7 3e-102 342.7 1.2 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase DUF159 PF02586.9 EXF75945.1 - 2e-53 181.0 0.0 3.5e-53 180.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, COG2135 bZIP_1 PF00170.16 EXF75946.1 - 5.4e-07 29.4 12.9 8.3e-07 28.8 9.0 1.2 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EXF75946.1 - 0.011 15.5 9.1 0.018 14.8 6.3 1.4 1 0 0 1 1 1 0 Basic region leucine zipper Ndc1_Nup PF09531.5 EXF75946.1 - 0.084 11.2 2.7 0.097 11.0 1.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MDFI PF15316.1 EXF75946.1 - 0.39 10.7 4.3 0.54 10.2 3.0 1.3 1 0 0 1 1 1 0 MyoD family inhibitor CDC45 PF02724.9 EXF75946.1 - 1.4 6.8 6.9 1.7 6.5 4.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Glyco_hydro_61 PF03443.9 EXF75947.1 - 3.8e-40 138.0 0.0 4.4e-40 137.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_61 PF03443.9 EXF75948.1 - 6.3e-36 124.2 0.0 8.2e-36 123.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Dsh_C PF12316.3 EXF75948.1 - 0.073 13.1 0.4 0.13 12.3 0.3 1.5 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Sugar_tr PF00083.19 EXF75949.1 - 4.5e-118 394.6 23.9 5.1e-118 394.5 16.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF75949.1 - 6.2e-18 64.6 31.8 6.2e-18 64.6 22.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_19 PF14559.1 EXF75949.1 - 0.047 14.0 0.0 0.094 13.0 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF3154 PF11351.3 EXF75949.1 - 1.4 8.6 6.1 1.2 8.8 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3154) 7tm_1 PF00001.16 EXF75949.1 - 2.8 7.0 9.8 2.7 7.0 0.0 2.9 2 1 1 3 3 3 0 7 transmembrane receptor (rhodopsin family) ADH_N PF08240.7 EXF75951.1 - 7e-24 83.6 1.7 1.3e-23 82.8 1.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_assoc PF13823.1 EXF75951.1 - 1.3e-09 37.5 1.5 1.3e-09 37.5 1.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-associated ADH_zinc_N PF00107.21 EXF75951.1 - 3.8e-06 26.4 0.1 0.00024 20.6 0.0 2.7 2 1 0 2 2 2 1 Zinc-binding dehydrogenase Oxidored_FMN PF00724.15 EXF75953.1 - 6e-35 120.8 0.0 1.1e-34 119.9 0.0 1.5 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans PF04082.13 EXF75954.1 - 8.4e-26 90.3 0.0 1.2e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF75954.1 - 4.6e-08 32.8 7.3 4.6e-08 32.8 5.0 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EndIII_4Fe-2S PF10576.4 EXF75954.1 - 2.8 8.2 7.7 8.5 6.7 1.5 2.6 1 1 1 2 2 2 0 Iron-sulfur binding domain of endonuclease III Pyr_redox_2 PF07992.9 EXF75955.1 - 5.6e-28 98.2 0.0 1.2e-27 97.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF75955.1 - 5.3e-14 52.3 1.1 5.3e-14 52.3 0.8 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rieske PF00355.21 EXF75955.1 - 1.1e-12 47.3 0.0 2.4e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EXF75955.1 - 1.3e-06 28.5 0.2 0.00096 19.2 0.0 3.3 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.1 EXF75955.1 - 7.3e-06 26.1 0.0 2e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Reductase C-terminal K_oxygenase PF13434.1 EXF75955.1 - 0.00022 20.2 0.0 0.47 9.3 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EXF75955.1 - 0.0013 18.5 2.9 0.42 10.3 0.0 3.2 3 0 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EXF75956.1 - 6.2e-64 216.2 0.4 2.7e-62 210.9 0.2 2.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF75956.1 - 2.2e-07 30.1 0.1 0.0028 16.6 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EXF75956.1 - 0.031 14.6 0.0 1.5 9.2 0.0 2.8 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF75956.1 - 0.042 13.8 0.0 0.1 12.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain GFO_IDH_MocA PF01408.17 EXF75957.1 - 4e-24 85.4 0.4 8.6e-24 84.3 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EXF75957.1 - 9e-05 22.8 0.1 0.00023 21.5 0.0 1.7 2 0 0 2 2 2 1 Homoserine dehydrogenase, NAD binding domain Iso_dh PF00180.15 EXF75958.1 - 1e-97 327.2 0.0 1.2e-97 326.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Sec5 PF15469.1 EXF75959.1 - 1e-36 126.3 0.0 7.9e-36 123.4 0.0 2.4 2 1 0 2 2 2 1 Exocyst complex component Sec5 Vps51 PF08700.6 EXF75959.1 - 0.00015 21.5 1.3 0.00038 20.2 0.1 2.4 2 0 0 2 2 2 1 Vps51/Vps67 Zn_clus PF00172.13 EXF75960.1 - 0.096 12.6 7.7 0.25 11.3 5.3 1.7 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain TFIIA PF03153.8 EXF75960.1 - 1.5 8.6 5.8 2.3 8.0 4.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_92 PF07971.7 EXF75961.1 - 7.2e-153 509.8 0.0 9.7e-153 509.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 Acetyltransf_1 PF00583.19 EXF75961.1 - 0.015 15.3 0.0 0.04 13.9 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Solute_trans_a PF03619.11 EXF75962.1 - 1.1e-104 349.6 7.5 1.3e-104 349.3 5.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha GTP_EFTU PF00009.22 EXF75964.1 - 1.1e-61 207.5 0.3 2.3e-61 206.5 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EXF75964.1 - 2.6e-36 123.7 0.0 7.1e-36 122.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EXF75964.1 - 2.6e-22 78.4 0.0 8.2e-22 76.8 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus RRM_6 PF14259.1 EXF75964.1 - 2.5e-12 46.5 0.1 2.1e-11 43.6 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) GTP_EFTU_D2 PF03144.20 EXF75964.1 - 3.4e-12 46.2 0.1 3.4e-12 46.2 0.1 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EXF75964.1 - 1.7e-11 43.8 0.0 4.5e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II RRM_5 PF13893.1 EXF75964.1 - 4.2e-09 36.1 0.0 4e-08 32.9 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EXF75964.1 - 9.7e-09 34.7 0.6 1e-06 28.2 0.0 3.3 3 0 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EXF75964.1 - 1.1e-08 34.7 0.0 0.007 16.1 0.0 2.7 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EXF75964.1 - 1.4e-05 24.6 2.8 2.6e-05 23.7 1.9 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) MMR_HSR1 PF01926.18 EXF75964.1 - 6.5e-05 22.8 0.3 0.00016 21.6 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Borrelia_P83 PF05262.6 EXF75964.1 - 0.0019 16.5 5.9 0.0035 15.7 4.1 1.4 1 0 0 1 1 1 1 Borrelia P83/100 protein DNA_mis_repair PF01119.14 EXF75964.1 - 0.03 13.7 0.0 1 8.8 0.0 2.4 2 0 0 2 2 2 0 DNA mismatch repair protein, C-terminal domain PduV-EutP PF10662.4 EXF75964.1 - 0.062 12.7 0.3 0.17 11.4 0.1 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IncA PF04156.9 EXF75964.1 - 2.2 7.8 12.4 4.5 6.8 8.6 1.4 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EXF75964.1 - 9.8 3.8 6.0 15 3.2 4.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4210 PF13915.1 EXF75965.1 - 6.8e-25 87.1 0.0 1.7e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) Chromosome_seg PF13889.1 EXF75965.1 - 4.1e-21 74.5 0.4 8.3e-21 73.6 0.3 1.5 1 0 0 1 1 1 1 Chromosome segregation during meiosis Cutinase PF01083.17 EXF75966.1 - 2.3e-43 147.9 0.0 3.1e-43 147.5 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EXF75966.1 - 0.0019 17.6 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 PE-PPE domain DUF2974 PF11187.3 EXF75966.1 - 0.0022 17.3 0.0 0.0036 16.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.20 EXF75966.1 - 0.0027 17.3 0.0 0.0043 16.6 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_8 PF06259.7 EXF75966.1 - 0.055 12.9 0.1 0.092 12.2 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase Abhydrolase_1 PF00561.15 EXF75966.1 - 0.055 13.0 0.0 0.073 12.6 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EXF75966.1 - 0.068 13.0 0.1 0.098 12.5 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family PPR_3 PF13812.1 EXF75967.1 - 4.1e-17 60.9 7.0 4.1e-05 23.5 0.0 9.5 9 0 0 9 9 9 3 Pentatricopeptide repeat domain PPR_2 PF13041.1 EXF75967.1 - 2.3e-14 53.0 2.3 5.5e-06 26.2 0.0 6.9 5 1 2 7 7 7 3 PPR repeat family PPR PF01535.15 EXF75967.1 - 2.4e-12 45.9 2.5 0.0022 17.8 0.0 7.0 7 0 0 7 7 7 3 PPR repeat PPR_1 PF12854.2 EXF75967.1 - 0.00015 21.1 0.1 0.22 11.0 0.0 5.2 6 0 0 6 6 6 1 PPR repeat TPR_14 PF13428.1 EXF75967.1 - 0.00028 21.2 6.7 7 7.5 0.0 6.9 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_2 PF07719.12 EXF75967.1 - 0.042 13.7 8.5 2.2 8.4 0.2 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EXF75967.1 - 0.14 12.0 8.9 0.67 9.9 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 EXF75967.1 - 0.39 10.4 3.9 11 5.8 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.12 EXF75967.1 - 0.5 10.6 11.2 4.7 7.5 0.0 3.8 3 0 0 3 3 3 0 Bacterial transcriptional activator domain P4Ha_N PF08336.6 EXF75968.1 - 0.0084 15.9 0.1 0.048 13.4 0.0 2.2 1 1 1 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region PMEI PF04043.10 EXF75968.1 - 0.017 15.0 0.6 0.017 15.0 0.4 3.5 3 1 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor Phage_lysozyme PF00959.14 EXF75968.1 - 0.018 15.3 0.3 0.17 12.1 0.1 2.5 2 0 0 2 2 2 0 Phage lysozyme PilJ PF13675.1 EXF75968.1 - 0.03 14.6 0.6 0.03 14.6 0.4 4.1 3 2 1 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF755 PF05501.6 EXF75968.1 - 0.14 12.2 0.1 0.14 12.2 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF755) HSP70 PF00012.15 EXF75969.1 - 4.7e-266 883.5 15.5 5.4e-266 883.2 10.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EXF75969.1 - 8.3e-16 57.4 4.1 7.8e-14 51.0 0.6 2.4 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EXF75969.1 - 0.00017 21.2 0.2 0.00063 19.4 0.0 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EXF75969.1 - 0.0064 16.3 9.6 1.1 9.1 0.8 4.4 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.13 EXF75969.1 - 3.6 6.6 9.2 1 8.3 0.4 3.5 3 1 0 3 3 3 0 Hydantoinase/oxoprolinase DUF2415 PF10313.4 EXF75970.1 - 1e-13 50.7 0.0 2.8e-13 49.2 0.0 1.8 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) DAO PF01266.19 EXF75971.1 - 2e-46 158.5 2.2 2.3e-46 158.3 1.6 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EXF75971.1 - 1.5e-05 25.1 0.1 0.0002 21.5 0.1 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF75971.1 - 0.00013 21.9 0.0 0.0003 20.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF676 PF05057.9 EXF75972.1 - 1.1e-42 145.8 0.2 2.3e-27 95.7 0.0 3.2 2 1 1 3 3 3 3 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EXF75972.1 - 0.0096 15.5 0.0 0.024 14.2 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EXF75972.1 - 0.013 15.2 0.0 0.034 13.8 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EXF75972.1 - 0.04 13.5 0.0 0.1 12.1 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein IBR PF01485.16 EXF75973.1 - 1.4e-10 40.8 49.5 6.2e-07 29.1 9.3 3.8 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 EXF75973.1 - 2.7e-05 23.9 6.6 2.7e-05 23.9 4.6 3.5 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EXF75973.1 - 0.00085 19.3 7.5 0.00085 19.3 5.2 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Nucleoplasmin PF03066.10 EXF75973.1 - 2 7.9 23.4 0.23 10.9 7.5 2.3 2 0 0 2 2 2 0 Nucleoplasmin TFIIF_alpha PF05793.7 EXF75973.1 - 5.7 5.1 32.8 10 4.3 22.7 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Zn_clus PF00172.13 EXF75974.1 - 1.3e-09 37.7 7.9 1.3e-09 37.7 5.5 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF75974.1 - 5.2e-08 32.0 0.1 8.1e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lactonase PF10282.4 EXF75975.1 - 4.2e-84 282.5 0.0 5.1e-84 282.2 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller PEMT PF04191.8 EXF75976.1 - 1.4e-55 185.9 10.9 5.6e-34 116.4 1.4 2.7 2 0 0 2 2 2 2 Phospholipid methyltransferase DUF4586 PF15239.1 EXF75977.1 - 0.023 14.2 3.4 0.042 13.4 2.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4586) eIF3g PF12353.3 EXF75978.1 - 1.2e-46 157.7 1.5 2e-46 157.0 1.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_1 PF00076.17 EXF75978.1 - 4.7e-16 58.1 0.1 8.3e-16 57.3 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF75978.1 - 1.4e-12 47.3 0.1 2.5e-12 46.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF75978.1 - 7.1e-07 28.9 0.0 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Leu_zip PF15294.1 EXF75980.1 - 0.05 12.7 1.9 0.08 12.0 0.0 1.9 2 0 0 2 2 2 0 Leucine zipper DUF2046 PF09755.4 EXF75980.1 - 0.054 12.3 1.7 0.12 11.2 1.2 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) TMCO5 PF14992.1 EXF75980.1 - 0.27 10.3 2.2 1.1 8.3 0.0 2.0 2 0 0 2 2 2 0 TMCO5 family Pox_A_type_inc PF04508.7 EXF75980.1 - 0.34 10.8 3.7 0.14 11.9 0.4 2.1 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF4075 PF13294.1 EXF75983.1 - 0.083 12.9 1.1 2.3 8.2 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4075) Tropomyosin_1 PF12718.2 EXF75983.1 - 0.6 9.9 18.3 0.069 12.9 7.8 2.5 3 0 0 3 3 3 0 Tropomyosin like DUF465 PF04325.8 EXF75984.1 - 0.023 14.3 1.6 0.24 11.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF465) DUF4398 PF14346.1 EXF75984.1 - 1.3 9.1 6.2 0.17 11.9 1.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) FKBP_C PF00254.23 EXF75987.1 - 7.2e-28 96.4 0.1 8.8e-28 96.1 0.1 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ThiF PF00899.16 EXF75988.1 - 2.6e-55 185.9 0.0 3.7e-33 114.2 0.0 2.9 3 0 0 3 3 3 2 ThiF family UBA_e1_C PF09358.5 EXF75988.1 - 3.6e-38 130.5 0.2 1.2e-37 128.8 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EXF75988.1 - 2.1e-37 126.5 3.8 5e-26 90.0 0.2 2.7 2 0 0 2 2 2 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EXF75988.1 - 6.5e-25 86.2 2.5 3.6e-20 71.0 0.4 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site GST_N_2 PF13409.1 EXF75988.1 - 5.2e-18 64.8 0.0 1.7e-17 63.1 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EXF75988.1 - 8.3e-13 48.0 0.0 2.2e-12 46.6 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EXF75988.1 - 0.00026 21.1 0.2 0.15 12.2 0.0 2.5 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EXF75988.1 - 0.0094 16.4 0.0 0.03 14.7 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Chitin_synth_2 PF03142.10 EXF75989.1 - 4e-253 840.6 1.8 6.1e-253 839.9 1.3 1.3 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EXF75989.1 - 6.2e-173 576.4 0.0 8.8e-173 575.9 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Cyt-b5 PF00173.23 EXF75989.1 - 1.6e-18 66.2 0.4 7.9e-14 51.2 0.1 2.9 2 1 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DEK_C PF08766.6 EXF75989.1 - 3.9e-18 64.9 0.3 3.2e-17 62.0 0.2 2.5 2 0 0 2 2 2 1 DEK C terminal domain Glyco_tranf_2_3 PF13641.1 EXF75989.1 - 2.2e-14 53.8 0.2 7.3e-11 42.3 0.0 2.5 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EXF75989.1 - 1.9e-13 50.5 5.6 1.9e-13 50.5 3.9 2.1 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EXF75989.1 - 1.2e-05 25.1 0.0 0.0026 17.4 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 MMR_HSR1 PF01926.18 EXF75989.1 - 0.0025 17.7 0.1 1.1 9.2 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EXF75989.1 - 0.0087 15.5 0.1 0.025 14.1 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EXF75989.1 - 0.027 14.5 0.6 0.27 11.3 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EXF75989.1 - 0.03 14.3 0.1 0.03 14.3 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain AAA_23 PF13476.1 EXF75989.1 - 0.032 14.5 1.1 0.3 11.3 0.1 2.3 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EXF75989.1 - 0.046 12.9 0.0 0.2 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Glyco_transf_21 PF13506.1 EXF75989.1 - 0.067 12.4 0.0 0.16 11.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 21 AAA_25 PF13481.1 EXF75989.1 - 0.07 12.5 0.1 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EXF75989.1 - 0.093 13.0 2.3 0.16 12.2 0.0 2.3 2 0 0 2 2 2 0 ABC transporter DUF2592 PF10766.4 EXF75989.1 - 6.5 6.1 7.4 1.2 8.5 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2592) Chitin_synth_2 PF03142.10 EXF75990.1 - 5e-229 761.0 0.0 6.9e-229 760.6 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Myosin_head PF00063.16 EXF75990.1 - 3.7e-60 203.7 0.0 2.5e-59 201.0 0.0 2.2 1 1 0 1 1 1 1 Myosin head (motor domain) Glyco_trans_2_3 PF13632.1 EXF75990.1 - 5.8e-19 68.5 1.9 1.4e-18 67.3 1.3 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Cyt-b5 PF00173.23 EXF75990.1 - 3.5e-16 58.7 0.0 5.5e-09 35.7 0.0 3.2 2 1 1 3 3 3 2 Cytochrome b5-like Heme/Steroid binding domain Glyco_tranf_2_3 PF13641.1 EXF75990.1 - 1.5e-14 54.3 0.0 7.3e-12 45.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 DEK_C PF08766.6 EXF75990.1 - 3.6e-13 49.0 0.6 4.9e-12 45.4 0.2 2.3 2 0 0 2 2 2 1 DEK C terminal domain Glyco_transf_21 PF13506.1 EXF75990.1 - 4.7e-06 25.9 0.0 2e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EXF75990.1 - 0.001 18.8 0.0 0.056 13.1 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 BCDHK_Adom3 PF10436.4 EXF75991.1 - 8.5e-45 152.2 0.0 1.1e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EXF75991.1 - 3.8e-17 62.0 0.0 1.7e-16 59.9 0.0 2.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EXF75991.1 - 0.025 14.3 0.0 0.071 12.8 0.0 1.9 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain HATPase_c_3 PF13589.1 EXF75991.1 - 0.055 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Inhibitor_I9 PF05922.11 EXF75992.1 - 2e-16 60.3 0.5 2.2e-16 60.1 0.4 1.0 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF663 PF04950.7 EXF75993.1 - 1e-88 297.1 0.0 1e-88 297.1 0.0 2.0 2 0 0 2 2 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EXF75993.1 - 2.1e-26 91.2 0.0 1.4e-25 88.6 0.0 2.4 2 0 0 2 2 2 1 AARP2CN (NUC121) domain AAA_16 PF13191.1 EXF75993.1 - 1.6e-05 24.9 0.1 6.7e-05 22.9 0.0 2.1 2 0 0 2 2 1 1 AAA ATPase domain GTP_EFTU PF00009.22 EXF75993.1 - 1.7e-05 24.3 0.8 0.0074 15.7 0.0 3.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EXF75993.1 - 1.8e-05 24.8 0.0 5.1e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EXF75993.1 - 0.00025 21.3 0.4 0.0027 18.0 0.0 2.6 2 0 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.18 EXF75993.1 - 0.00028 20.8 0.0 0.00087 19.2 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 EXF75993.1 - 0.00031 20.4 0.0 0.00075 19.1 0.0 1.7 1 1 0 1 1 1 1 NACHT domain AAA PF00004.24 EXF75993.1 - 0.00034 20.8 0.0 0.00092 19.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EXF75993.1 - 0.00063 19.4 0.6 0.002 17.8 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain Miro PF08477.8 EXF75993.1 - 0.00063 20.2 0.0 0.0032 17.9 0.0 2.2 1 0 0 1 1 1 1 Miro-like protein AAA_25 PF13481.1 EXF75993.1 - 0.001 18.5 0.0 0.0027 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EXF75993.1 - 0.0011 18.8 1.3 0.0038 17.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EXF75993.1 - 0.0019 18.9 0.0 0.0019 18.9 0.0 4.8 3 1 1 5 5 3 1 AAA domain MobB PF03205.9 EXF75993.1 - 0.0021 17.7 0.2 0.01 15.5 0.1 2.2 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EXF75993.1 - 0.0024 17.0 0.0 0.047 12.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 EXF75993.1 - 0.0028 17.5 0.0 0.0088 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EXF75993.1 - 0.0036 16.7 0.0 0.014 14.9 0.0 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 EXF75993.1 - 0.0052 16.2 0.0 0.012 15.0 0.0 1.7 2 0 0 2 2 1 1 AAA-like domain NTPase_1 PF03266.10 EXF75993.1 - 0.0054 16.4 0.2 0.015 14.9 0.1 1.8 1 0 0 1 1 1 1 NTPase RNA_helicase PF00910.17 EXF75993.1 - 0.0062 16.7 0.0 0.019 15.1 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 EXF75993.1 - 0.0063 16.8 0.0 0.0063 16.8 0.0 4.5 4 2 1 5 5 4 1 AAA domain cobW PF02492.14 EXF75993.1 - 0.013 14.9 0.0 0.029 13.8 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EXF75993.1 - 0.016 14.9 1.5 0.16 11.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 EXF75993.1 - 0.02 13.7 0.0 0.046 12.5 0.0 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.1 EXF75993.1 - 0.031 13.8 0.1 0.031 13.8 0.0 2.6 3 0 0 3 3 2 0 AAA domain WD40 PF00400.27 EXF75994.1 - 1.7e-19 68.8 2.1 7e-05 22.5 0.0 4.7 4 0 0 4 4 4 4 WD domain, G-beta repeat Mo-co_dimer PF03404.11 EXF75994.1 - 0.013 15.0 0.1 0.025 14.2 0.1 1.4 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Fungal_trans_2 PF11951.3 EXF75995.1 - 1.9e-06 26.7 0.8 2.7e-06 26.2 0.6 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Arm PF00514.18 EXF75995.1 - 0.11 12.3 0.1 1.5 8.7 0.0 2.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF4070 PF13282.1 EXF75995.1 - 0.12 11.8 0.2 1.8 8.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4070) MFS_1 PF07690.11 EXF75996.1 - 1.1e-42 146.0 59.0 1.4e-41 142.3 40.1 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF75996.1 - 8.7e-09 34.4 19.3 8.7e-09 34.4 13.4 3.6 2 2 2 4 4 4 2 Sugar (and other) transporter NDUF_B12 PF08122.7 EXF75996.1 - 0.45 10.2 4.0 14 5.5 0.0 3.6 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B12 subunit family Fungal_trans PF04082.13 EXF75997.1 - 2.8e-16 59.1 0.0 4.3e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF75997.1 - 8.6e-09 35.1 11.5 1.4e-08 34.5 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_15 PF00723.16 EXF75998.1 - 2.1e-84 283.6 0.1 2.6e-84 283.3 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EXF75998.1 - 1.6e-21 75.6 0.0 5.3e-21 74.0 0.0 1.9 1 0 0 1 1 1 1 Starch binding domain p450 PF00067.17 EXF75999.1 - 9.8e-48 162.8 0.0 1.3e-47 162.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 EXF76000.1 - 0.0022 17.7 0.0 0.14 11.8 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 EXF76000.1 - 0.099 12.2 0.0 1.1 8.8 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EXF76001.1 - 1.8e-16 60.2 0.0 2.5e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF76001.1 - 3.2e-10 40.3 0.0 5.4e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF76001.1 - 1.5e-09 38.3 0.0 3.6e-09 37.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF76001.1 - 5.2e-09 36.4 0.0 2.5e-08 34.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF76001.1 - 8.5e-09 35.1 0.0 2.1e-08 33.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF76001.1 - 5.3e-05 22.3 0.0 0.00012 21.2 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EXF76001.1 - 0.00029 21.1 0.0 0.00061 20.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF76001.1 - 0.0016 17.6 0.0 0.045 12.8 0.0 2.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EXF76001.1 - 0.0052 16.8 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 EXF76001.1 - 0.0064 15.6 0.0 0.0099 15.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EXF76001.1 - 0.016 14.5 0.0 0.027 13.8 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.13 EXF76001.1 - 0.041 13.0 0.0 0.059 12.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_26 PF13659.1 EXF76001.1 - 0.11 12.5 0.0 0.33 10.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain UPF0146 PF03686.8 EXF76001.1 - 0.13 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) CMAS PF02353.15 EXF76001.1 - 0.16 11.0 0.0 0.27 10.2 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase CDC45 PF02724.9 EXF76003.1 - 1.6e-238 792.8 0.0 2.1e-238 792.4 0.0 1.3 1 0 0 1 1 1 1 CDC45-like protein Hemerythrin PF01814.18 EXF76004.1 - 3.3e-10 40.2 0.5 4.4e-10 39.8 0.3 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain EF-hand_1 PF00036.27 EXF76005.1 - 2.4e-24 82.7 13.5 3.8e-08 32.0 0.2 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.1 EXF76005.1 - 5.8e-24 81.7 4.3 7.1e-06 25.4 0.1 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_7 PF13499.1 EXF76005.1 - 4e-22 78.1 4.8 5e-14 52.1 0.6 3.1 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EXF76005.1 - 7e-17 59.9 14.5 2.5e-05 23.3 0.0 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 EXF76005.1 - 3.6e-15 55.2 12.7 1.7e-05 24.3 0.9 4.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 EXF76005.1 - 3.6e-09 36.3 8.1 0.0039 16.9 0.1 4.0 1 1 2 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EXF76005.1 - 0.0001 22.1 0.4 0.022 14.6 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.4 EXF76005.1 - 0.0012 18.8 2.2 0.45 10.5 0.1 3.0 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EXF76005.1 - 0.003 17.2 3.4 0.32 10.7 0.0 4.0 4 0 0 4 4 4 1 EF hand EF-hand_2 PF09068.6 EXF76005.1 - 0.021 14.8 0.1 2.9 7.9 0.0 3.1 3 1 1 4 4 4 0 EF hand DUF1679 PF07914.6 EXF76005.1 - 0.022 13.3 0.5 1.7 7.1 0.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1679) Toprim PF01751.17 EXF76005.1 - 0.027 14.4 0.0 8.8 6.3 0.0 2.3 1 1 1 2 2 2 0 Toprim domain AMP-binding PF00501.23 EXF76006.1 - 4.8e-79 265.6 0.0 7.2e-79 265.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme CdhD PF03599.11 EXF76006.1 - 0.036 12.5 0.0 0.059 11.8 0.0 1.2 1 0 0 1 1 1 0 CO dehydrogenase/acetyl-CoA synthase delta subunit 5-FTHF_cyc-lig PF01812.15 EXF76007.1 - 8.5e-27 94.1 0.0 1.1e-26 93.7 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family LSM PF01423.17 EXF76008.1 - 3.9e-16 58.3 0.2 5e-16 58.0 0.1 1.1 1 0 0 1 1 1 1 LSM domain PhnA PF03831.9 EXF76008.1 - 0.096 12.1 0.0 0.49 9.8 0.0 2.0 2 0 0 2 2 2 0 PhnA protein Xpo1 PF08389.7 EXF76009.1 - 3.4e-29 101.6 0.9 7.6e-27 94.0 0.1 4.1 3 1 1 4 4 4 1 Exportin 1-like protein IBN_N PF03810.14 EXF76009.1 - 1e-06 28.5 0.1 5.5e-06 26.2 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT_2 PF13646.1 EXF76009.1 - 0.00035 20.8 1.1 0.051 13.8 0.0 4.2 4 2 1 5 5 5 1 HEAT repeats CSTF2_hinge PF14327.1 EXF76009.1 - 0.035 14.1 0.8 6.5 6.9 0.0 3.5 4 0 0 4 4 4 0 Hinge domain of cleavage stimulation factor subunit 2 Adaptin_N PF01602.15 EXF76009.1 - 0.043 12.1 1.1 3.1 6.0 0.1 2.6 2 0 0 2 2 2 0 Adaptin N terminal region ECM11 PF15463.1 EXF76010.1 - 1e-40 139.2 3.9 1e-40 139.2 2.7 2.1 2 0 0 2 2 2 1 Extracellular mutant protein 11 AAA_17 PF13207.1 EXF76011.1 - 4.3e-06 27.5 0.0 1.5e-05 25.7 0.0 1.9 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.17 EXF76011.1 - 1.4e-05 24.6 0.0 2.2e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_18 PF13238.1 EXF76011.1 - 9.9e-05 22.6 0.2 0.00052 20.3 0.0 2.1 2 1 0 2 2 2 1 AAA domain ArgK PF03308.11 EXF76011.1 - 0.00019 20.3 0.0 0.00031 19.6 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA_16 PF13191.1 EXF76011.1 - 0.00029 20.8 0.2 0.00054 19.9 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain NACHT PF05729.7 EXF76011.1 - 0.0013 18.4 0.0 0.0025 17.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 EXF76011.1 - 0.0023 17.0 0.0 0.0028 16.6 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain AAA_14 PF13173.1 EXF76011.1 - 0.0023 17.8 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EXF76011.1 - 0.0026 16.8 0.1 0.0047 16.0 0.1 1.3 1 0 0 1 1 1 1 Anion-transporting ATPase Zeta_toxin PF06414.7 EXF76011.1 - 0.0041 16.2 0.0 0.0065 15.5 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin PRK PF00485.13 EXF76011.1 - 0.0043 16.6 0.0 0.018 14.5 0.0 1.8 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA PF00004.24 EXF76011.1 - 0.0053 16.9 0.0 0.016 15.3 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EXF76011.1 - 0.0054 16.3 0.1 0.045 13.3 0.1 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 EXF76011.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein YhjQ PF06564.7 EXF76011.1 - 0.013 14.8 0.2 0.028 13.7 0.0 1.6 2 0 0 2 2 2 0 YhjQ protein MobB PF03205.9 EXF76011.1 - 0.013 15.1 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EXF76011.1 - 0.015 14.6 0.4 0.018 14.4 0.3 1.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EXF76011.1 - 0.018 14.9 0.0 0.03 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EXF76011.1 - 0.024 14.2 0.0 0.077 12.6 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_33 PF13671.1 EXF76011.1 - 0.038 13.8 0.1 0.081 12.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 EXF76011.1 - 0.04 13.2 0.0 0.072 12.4 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase NB-ARC PF00931.17 EXF76011.1 - 0.074 11.8 0.2 0.2 10.4 0.1 1.7 1 1 1 2 2 2 0 NB-ARC domain NTPase_1 PF03266.10 EXF76011.1 - 0.079 12.6 0.2 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 NTPase AAA_28 PF13521.1 EXF76011.1 - 0.082 12.8 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF4355 PF14265.1 EXF76011.1 - 0.086 12.8 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Helicase_C_3 PF13625.1 EXF76011.1 - 0.095 12.4 0.1 0.24 11.1 0.0 1.7 2 0 0 2 2 2 0 Helicase conserved C-terminal domain AAA_19 PF13245.1 EXF76011.1 - 0.13 12.0 0.1 0.6 9.9 0.1 2.0 2 0 0 2 2 2 0 Part of AAA domain adh_short PF00106.20 EXF76012.1 - 3e-62 209.4 5.6 2.9e-31 108.6 0.4 2.3 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EXF76012.1 - 1.8e-31 109.1 0.9 3.3e-15 56.2 0.0 2.3 2 0 0 2 2 2 2 KR domain MaoC_dehydratas PF01575.14 EXF76012.1 - 4.8e-31 106.7 0.0 1.2e-30 105.4 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EXF76012.1 - 2.6e-07 30.4 0.0 1.6e-05 24.7 0.0 2.7 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase Epimerase PF01370.16 EXF76012.1 - 6.6e-05 22.4 3.4 0.0057 16.1 0.1 2.8 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EXF76012.1 - 6.7e-05 22.0 1.3 0.0074 15.3 0.3 2.5 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EXF76012.1 - 2.1 8.2 5.5 1.6 8.6 0.1 2.5 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase IBR PF01485.16 EXF76013.1 - 7.6e-07 28.9 5.3 7.6e-07 28.9 3.7 4.3 4 1 0 4 4 4 2 IBR domain DUF4650 PF15509.1 EXF76013.1 - 0.13 11.1 3.3 0.19 10.6 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4650) RAP1 PF07218.6 EXF76013.1 - 1 7.3 1.6 1.4 6.8 1.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) adh_short PF00106.20 EXF76014.1 - 6.1e-35 120.6 0.0 8.6e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF76014.1 - 3.1e-15 56.6 0.0 3.8e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF76014.1 - 1e-14 54.5 0.0 1.5e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EXF76014.1 - 0.00031 20.4 0.1 0.00077 19.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Saccharop_dh PF03435.13 EXF76014.1 - 0.0024 16.9 0.0 0.0034 16.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EXF76014.1 - 0.0085 15.0 0.5 0.016 14.1 0.1 1.5 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein MFS_1 PF07690.11 EXF76015.1 - 3.6e-41 141.0 45.3 9.4e-40 136.3 31.2 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF76015.1 - 1.4e-13 50.2 11.6 1.4e-13 50.2 8.0 2.5 2 1 1 3 3 3 1 Sugar (and other) transporter Glycos_trans_3N PF02885.12 EXF76015.1 - 0.01 15.4 0.1 0.02 14.4 0.1 1.5 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain ThiF PF00899.16 EXF76016.1 - 3e-13 49.7 0.0 7e-13 48.5 0.0 1.7 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EXF76016.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.5 1 0 0 1 1 1 0 MoeZ/MoeB domain Fungal_trans PF04082.13 EXF76017.1 - 1.9e-27 95.7 0.0 3.1e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF76017.1 - 2.9e-07 30.2 12.6 5.1e-07 29.4 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BatA PF07584.6 EXF76017.1 - 2.8 8.2 7.2 34 4.7 0.0 4.5 5 0 0 5 5 5 0 Aerotolerance regulator N-terminal zf-RING_5 PF14634.1 EXF76018.1 - 2.5e-07 30.3 11.6 4.4e-07 29.5 8.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EXF76018.1 - 2.3e-05 24.3 4.5 5e-05 23.2 3.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EXF76018.1 - 6.6e-05 22.6 7.0 0.00013 21.7 4.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EXF76018.1 - 0.00021 20.8 7.5 0.00037 20.0 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF948 PF06103.6 EXF76018.1 - 0.055 13.3 0.3 0.092 12.6 0.2 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 EXF76018.1 - 0.078 12.5 4.0 0.12 11.9 2.8 1.2 1 0 0 1 1 1 0 IncA protein Mito_carr PF00153.22 EXF76018.1 - 0.091 12.4 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial carrier protein Peptidase_M13 PF01431.16 EXF76018.1 - 0.11 11.6 0.4 0.2 10.7 0.2 1.4 1 0 0 1 1 1 0 Peptidase family M13 Syntaxin_2 PF14523.1 EXF76018.1 - 0.12 12.4 4.0 0.21 11.6 2.8 1.4 1 0 0 1 1 1 0 Syntaxin-like protein DUF3584 PF12128.3 EXF76018.1 - 0.21 8.8 6.2 0.26 8.5 4.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) zf-RING_UBOX PF13445.1 EXF76018.1 - 2.7 7.7 8.1 5.4 6.8 5.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger GDA1_CD39 PF01150.12 EXF76019.1 - 6e-102 341.3 0.0 8.2e-102 340.9 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family DUF775 PF05603.7 EXF76020.1 - 3.2e-53 180.2 0.1 3.6e-53 180.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF775) NUDIX PF00293.23 EXF76021.1 - 2.8e-09 36.7 0.1 5.2e-09 35.8 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain RNA_pol_Rpb8 PF03870.10 EXF76022.1 - 4.7e-39 133.7 0.2 5.3e-39 133.5 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 PAXNEB PF05625.6 EXF76023.1 - 8.8e-96 320.8 0.0 9.8e-96 320.7 0.0 1.0 1 0 0 1 1 1 1 PAXNEB protein tRNA_int_endo PF01974.12 EXF76024.1 - 2.6e-15 55.9 0.0 4.6e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain ING PF12998.2 EXF76024.1 - 0.047 13.9 0.5 0.073 13.3 0.4 1.2 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding zf-C3HC4_3 PF13920.1 EXF76025.1 - 4.9e-08 32.5 12.8 8e-08 31.8 8.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FAM24 PF15193.1 EXF76025.1 - 2 8.6 9.1 4 7.6 6.3 1.5 1 0 0 1 1 1 0 FAM24 family RNase_PH PF01138.16 EXF76026.1 - 1.2e-27 96.8 0.1 2.3e-27 95.9 0.0 1.5 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Anp1 PF03452.9 EXF76027.1 - 1.1e-121 405.1 0.7 6.3e-121 402.6 0.0 2.0 2 0 0 2 2 2 1 Anp1 DUF2146 PF10220.4 EXF76027.1 - 2.5 5.9 11.0 3.4 5.5 7.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) Sec7 PF01369.15 EXF76028.1 - 5.3e-62 208.8 0.0 9.5e-62 208.0 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EXF76028.1 - 3e-17 62.5 0.0 3.8e-11 42.6 0.0 2.9 3 0 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal RRM_1 PF00076.17 EXF76029.1 - 3.2e-25 87.5 0.8 2.4e-12 46.3 0.2 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF76029.1 - 6.4e-19 67.6 0.1 2.6e-08 33.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF76029.1 - 5.7e-17 61.3 0.0 1e-09 38.0 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1866 PF08952.6 EXF76029.1 - 0.018 14.5 0.0 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) Limkain-b1 PF11608.3 EXF76029.1 - 0.02 14.6 0.0 2.6 7.8 0.0 2.6 2 0 0 2 2 2 0 Limkain b1 ATP-synt_D PF01813.12 EXF76030.1 - 2.3e-64 216.5 1.5 2.8e-64 216.2 1.0 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Viral_P18 PF04521.8 EXF76030.1 - 0.4 10.1 3.2 3.8 6.9 0.1 2.3 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein TPR_12 PF13424.1 EXF76031.1 - 5e-11 42.3 2.0 0.49 10.3 0.0 7.4 7 1 1 8 8 8 3 Tetratricopeptide repeat Suf PF05843.9 EXF76031.1 - 4.1e-09 36.5 9.3 0.061 13.0 0.0 5.6 5 1 0 6 6 6 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EXF76031.1 - 2.7e-08 33.7 19.6 1.2 9.9 0.0 10.7 10 3 3 13 13 12 2 Tetratricopeptide repeat TPR_15 PF13429.1 EXF76031.1 - 7.3e-07 28.5 5.1 0.00015 20.9 0.7 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EXF76031.1 - 2e-06 27.3 5.3 1.4 8.5 0.0 6.7 8 2 1 9 9 8 1 TPR repeat NRDE-2 PF08424.5 EXF76031.1 - 0.00012 21.0 8.4 0.26 10.1 0.1 6.0 2 2 3 5 5 5 2 NRDE-2, necessary for RNA interference RPN7 PF10602.4 EXF76031.1 - 0.00089 18.6 0.6 0.0088 15.4 0.1 2.9 2 2 0 3 3 3 1 26S proteasome subunit RPN7 Mad3_BUB1_I PF08311.7 EXF76031.1 - 0.0012 18.6 8.9 1.2 8.9 0.1 5.9 7 0 0 7 7 7 2 Mad3/BUB1 homology region 1 TPR_8 PF13181.1 EXF76031.1 - 0.002 17.7 2.7 0.63 9.9 0.0 5.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_2 PF07719.12 EXF76031.1 - 0.0027 17.4 15.5 1.7 8.7 0.0 7.2 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_16 PF13432.1 EXF76031.1 - 0.015 15.9 12.4 0.16 12.7 0.0 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat PPR_3 PF13812.1 EXF76031.1 - 0.12 12.7 0.4 2.1 8.8 0.0 3.4 3 0 0 3 3 2 0 Pentatricopeptide repeat domain TPR_17 PF13431.1 EXF76031.1 - 0.81 10.0 3.5 44 4.6 0.0 5.4 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 EXF76031.1 - 4.2 7.4 7.7 21 5.1 0.0 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3129 PF11327.3 EXF76033.1 - 9.6e-60 201.5 11.4 1.2e-59 201.1 7.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) PolyA_pol PF01743.15 EXF76034.1 - 6e-26 91.1 0.1 1.2e-25 90.1 0.0 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EXF76034.1 - 1.2e-06 28.0 0.0 2.7e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EXF76034.1 - 0.005 16.6 0.0 0.0093 15.7 0.0 1.4 1 0 0 1 1 1 1 tRNA nucleotidyltransferase domain 2 putative DUF2454 PF10521.4 EXF76035.1 - 1.8e-11 43.5 0.1 2.9e-11 42.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2454) Syja_N PF02383.13 EXF76036.1 - 7.7e-90 300.8 0.0 1.9e-89 299.5 0.0 1.6 2 0 0 2 2 2 1 SacI homology domain Seryl_tRNA_N PF02403.17 EXF76037.1 - 0.015 15.3 1.1 0.015 15.3 0.8 2.8 3 1 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Filament PF00038.16 EXF76037.1 - 0.061 12.7 4.8 0.14 11.6 0.2 2.6 2 1 0 2 2 2 0 Intermediate filament protein DUF848 PF05852.6 EXF76037.1 - 0.33 10.7 5.7 0.066 13.0 0.3 2.4 3 0 0 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) CENP-F_leu_zip PF10473.4 EXF76037.1 - 3.7 7.4 12.9 1.6 8.6 1.5 3.8 2 2 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Suppressor_APC PF11414.3 EXF76037.1 - 5.8 6.7 8.0 0.47 10.2 0.4 2.7 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein WD40 PF00400.27 EXF76038.1 - 1.1e-19 69.5 7.3 5.9e-07 29.1 0.0 5.0 4 0 0 4 4 4 4 WD domain, G-beta repeat ADH_zinc_N PF00107.21 EXF76039.1 - 5.5e-31 106.8 0.1 9.8e-31 106.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF76039.1 - 2.6e-12 47.7 0.0 4.7e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF76039.1 - 1.9e-08 34.0 0.0 1.8e-07 30.8 0.0 2.2 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain CTD PF12815.2 EXF76040.1 - 4.9e-25 88.3 54.7 1.4e-19 70.7 23.4 4.0 1 1 2 3 3 3 2 Spt5 C-terminal nonapeptide repeat binding Spt4 Spt5-NGN PF03439.8 EXF76040.1 - 6.2e-25 86.7 0.0 1e-24 86.0 0.0 1.4 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 EXF76040.1 - 2e-19 69.9 10.5 2e-19 69.9 7.3 3.5 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal KOW PF00467.24 EXF76040.1 - 1.6e-05 24.4 18.6 0.0003 20.3 0.2 5.3 6 0 0 6 6 6 2 KOW motif Oxidored_molyb PF00174.14 EXF76041.1 - 4.2e-55 185.7 0.0 6e-55 185.2 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EXF76041.1 - 1.8e-29 101.9 0.1 3.5e-29 101.0 0.1 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.23 EXF76041.1 - 9.8e-13 47.7 0.1 1.9e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain mRNA_triPase PF02940.10 EXF76042.1 - 2.6e-53 180.9 0.0 3.8e-53 180.4 0.0 1.3 1 0 0 1 1 1 1 mRNA capping enzyme, beta chain PC_rep PF01851.17 EXF76043.1 - 7.7e-43 142.3 14.7 5.5e-08 32.6 0.0 9.7 9 0 0 9 9 9 8 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EXF76043.1 - 8.9e-18 64.3 0.0 4e-12 46.2 0.0 5.2 3 1 2 5 5 5 3 HEAT repeats HEAT PF02985.17 EXF76043.1 - 4.9e-07 29.2 3.8 2.3 8.5 0.0 6.5 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.1 EXF76043.1 - 2.8e-06 27.6 0.6 0.00098 19.5 0.0 4.9 4 1 0 4 4 4 1 HEAT-like repeat Transaldolase PF00923.14 EXF76044.1 - 1.8e-45 155.2 0.0 2.1e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 Transaldolase AA_permease_2 PF13520.1 EXF76045.1 - 5.1e-62 209.7 28.4 1.5e-61 208.2 18.7 2.3 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF76045.1 - 1e-13 50.5 20.9 1e-13 50.5 14.5 3.3 2 2 0 2 2 2 1 Amino acid permease Xan_ur_permease PF00860.15 EXF76047.1 - 4.7e-63 212.9 34.9 5.3e-62 209.5 24.2 2.0 1 1 0 1 1 1 1 Permease family Transp_cyt_pur PF02133.10 EXF76048.1 - 1.3e-92 310.7 36.0 1.5e-92 310.5 24.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DHquinase_I PF01487.10 EXF76049.1 - 1.5e-40 139.1 0.0 2.4e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 EXF76049.1 - 8e-22 77.1 0.0 2.3e-21 75.6 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 EXF76049.1 - 2.8e-16 59.7 0.1 5.7e-16 58.7 0.1 1.5 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.15 EXF76049.1 - 9.1e-11 42.0 0.1 2.3e-10 40.7 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EXF76049.1 - 0.092 13.1 0.0 0.33 11.4 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AAA_25 PF13481.1 EXF76049.1 - 0.13 11.6 0.0 1 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EXF76049.1 - 0.15 12.8 0.0 0.49 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EXF76049.1 - 0.15 11.0 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Fungal_trans PF04082.13 EXF76050.1 - 2e-12 46.5 0.0 2.7e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF76050.1 - 0.00015 21.6 1.2 0.00032 20.5 0.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1688 PF07958.6 EXF76050.1 - 0.003 16.1 0.0 0.0045 15.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) Vpu PF00558.14 EXF76050.1 - 0.084 12.4 0.1 0.17 11.4 0.1 1.4 1 0 0 1 1 1 0 Vpu protein Sugar_tr PF00083.19 EXF76051.1 - 3.1e-131 438.0 28.1 3.5e-131 437.8 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF76051.1 - 5.6e-23 81.2 36.5 5.6e-23 81.2 25.3 2.1 1 1 0 2 2 2 1 Major Facilitator Superfamily Shikimate_dh_N PF08501.6 EXF76052.1 - 6.4e-22 77.4 0.0 1.2e-21 76.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EXF76052.1 - 2.1e-17 63.4 0.0 3.5e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AP_endonuc_2 PF01261.19 EXF76053.1 - 2.7e-29 102.0 0.1 3.8e-29 101.5 0.1 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Inositol_P PF00459.20 EXF76054.1 - 3.6e-77 259.3 0.0 4e-77 259.1 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family Fe-ADH PF00465.14 EXF76055.1 - 7.2e-63 212.4 2.8 3.4e-62 210.2 2.0 1.8 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EXF76055.1 - 2.6e-13 49.8 0.0 5.3e-13 48.8 0.0 1.5 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase WD40 PF00400.27 EXF76056.1 - 1.1e-10 40.9 4.8 0.00091 19.0 0.2 5.1 4 1 0 4 4 4 3 WD domain, G-beta repeat CDC45 PF02724.9 EXF76056.1 - 0.17 9.9 8.1 0.27 9.2 5.6 1.2 1 0 0 1 1 1 0 CDC45-like protein PQQ_3 PF13570.1 EXF76056.1 - 0.34 11.2 2.6 13 6.2 0.0 3.5 3 0 0 3 3 3 0 PQQ-like domain Nop14 PF04147.7 EXF76056.1 - 5.3 4.8 9.4 7 4.4 6.5 1.1 1 0 0 1 1 1 0 Nop14-like family Glyco_hydro_18 PF00704.23 EXF76057.1 - 1.4e-49 169.3 0.0 1.8e-49 169.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 MARVEL PF01284.18 EXF76058.1 - 1e-16 61.0 20.6 1.4e-16 60.5 14.3 1.2 1 0 0 1 1 1 1 Membrane-associating domain GDPD PF03009.12 EXF76059.1 - 1e-12 48.1 0.0 1.2e-12 47.8 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Diphthamide_syn PF01866.12 EXF76060.1 - 3.4e-52 177.6 0.0 8e-52 176.3 0.0 1.5 1 1 0 1 1 1 1 Putative diphthamide synthesis protein MARVEL PF01284.18 EXF76061.1 - 0.00086 19.1 15.7 0.0012 18.6 10.9 1.2 1 0 0 1 1 1 1 Membrane-associating domain UNC-50 PF05216.8 EXF76061.1 - 0.014 14.6 1.7 0.014 14.6 1.2 1.9 3 0 0 3 3 3 0 UNC-50 family 7TMR-DISM_7TM PF07695.6 EXF76061.1 - 0.044 13.4 17.6 0.7 9.5 8.7 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling TspO_MBR PF03073.10 EXF76061.1 - 0.091 12.2 11.3 0.15 11.5 0.0 2.2 2 0 0 2 2 2 0 TspO/MBR family PAH PF02671.16 EXF76062.1 - 1.1e-43 146.5 2.8 7.4e-18 63.8 0.5 3.5 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EXF76062.1 - 5.6e-38 128.7 0.0 1.5e-37 127.4 0.0 1.8 1 0 0 1 1 1 1 Sin3 family co-repressor Fasciclin PF02469.17 EXF76063.1 - 0.016 15.2 0.0 0.026 14.5 0.0 1.3 1 1 0 1 1 1 0 Fasciclin domain FAD_binding_2 PF00890.19 EXF76064.1 - 4.9e-83 279.2 0.7 6e-83 279.0 0.5 1.1 1 0 0 1 1 1 1 FAD binding domain Cyt-b5 PF00173.23 EXF76064.1 - 3.3e-20 71.6 0.6 2.7e-19 68.7 0.0 2.8 4 0 0 4 4 4 1 Cytochrome b5-like Heme/Steroid binding domain DAO PF01266.19 EXF76064.1 - 3.1e-12 46.0 1.6 1.4e-11 43.8 1.1 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EXF76064.1 - 8.5e-10 38.2 0.5 3.8e-09 36.1 0.3 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF76064.1 - 2.4e-08 33.8 2.8 1.2e-07 31.6 0.4 2.9 2 1 1 3 3 3 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF76064.1 - 4.8e-08 33.1 0.0 5.1e-06 26.5 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF76064.1 - 5.8e-05 21.7 3.9 0.0064 15.0 0.3 3.3 3 1 0 3 3 3 1 HI0933-like protein Thi4 PF01946.12 EXF76064.1 - 9.6e-05 21.5 1.2 0.013 14.6 0.3 2.6 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.14 EXF76064.1 - 0.00059 18.9 1.9 0.0016 17.5 1.3 1.7 1 1 0 1 1 1 1 FAD binding domain GIDA PF01134.17 EXF76064.1 - 0.0072 15.2 3.7 0.14 11.0 1.0 2.3 2 0 0 2 2 2 1 Glucose inhibited division protein A Amino_oxidase PF01593.19 EXF76064.1 - 0.019 14.0 0.5 0.2 10.6 0.1 2.3 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EXF76064.1 - 0.024 14.6 0.1 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF76064.1 - 0.048 13.4 0.2 0.5 10.1 0.1 2.7 2 1 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EXF76064.1 - 0.3 11.5 2.9 1.7 9.1 0.6 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_23 PF13489.1 EXF76065.1 - 1.8e-16 60.3 0.0 2.8e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF76065.1 - 5.9e-09 36.4 0.0 2e-08 34.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF76065.1 - 8e-09 35.2 0.0 2.3e-08 33.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF76065.1 - 3.5e-05 24.1 0.0 6.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF76065.1 - 6.5e-05 23.3 0.0 0.00022 21.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF76065.1 - 0.0057 15.7 0.0 0.011 14.7 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EXF76065.1 - 0.0071 16.6 0.0 0.013 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF76065.1 - 0.015 15.3 0.0 0.028 14.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EXF76065.1 - 0.023 14.1 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 EXF76065.1 - 0.049 13.6 0.0 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EXF76065.1 - 0.057 12.8 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase CMAS PF02353.15 EXF76065.1 - 0.065 12.3 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 EXF76065.1 - 0.14 11.2 0.0 0.77 8.8 0.0 1.9 2 0 0 2 2 2 0 O-methyltransferase DUF1708 PF08101.6 EXF76067.1 - 2.4e-158 527.3 0.0 4.6e-158 526.4 0.0 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1708) Flavokinase PF01687.12 EXF76068.1 - 0.019 14.8 0.0 0.02 14.7 0.0 1.1 1 0 0 1 1 1 0 Riboflavin kinase NAD_binding_10 PF13460.1 EXF76069.1 - 1.3e-10 41.5 0.6 1.8e-10 41.1 0.4 1.1 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF76069.1 - 9.5e-07 28.4 0.0 1.5e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EXF76069.1 - 0.00043 19.6 0.4 0.0017 17.6 0.2 1.8 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EXF76069.1 - 0.024 14.9 0.0 0.046 14.0 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EXF76069.1 - 0.027 13.1 0.0 0.057 12.1 0.0 1.6 1 1 1 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EXF76069.1 - 0.073 11.9 0.1 14 4.5 0.0 2.8 2 1 0 2 2 2 0 Male sterility protein zf-RING_2 PF13639.1 EXF76070.1 - 8.2e-11 41.5 4.6 1.3e-10 40.8 3.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EXF76070.1 - 5.9e-08 32.7 0.7 1.1e-07 31.7 0.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EXF76070.1 - 7.3e-07 28.9 0.9 1.2e-06 28.2 0.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EXF76070.1 - 3.4e-05 23.7 4.9 5.5e-05 23.1 3.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EXF76070.1 - 3.5e-05 23.3 2.0 5.8e-05 22.6 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EXF76070.1 - 0.00093 18.8 3.2 0.0015 18.1 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 EXF76070.1 - 0.0043 16.5 2.5 0.83 9.1 0.3 2.7 2 0 0 2 2 2 2 Rad50 zinc hook motif FANCL_C PF11793.3 EXF76070.1 - 0.005 16.7 2.6 0.22 11.5 2.0 2.5 2 1 0 2 2 1 1 FANCL C-terminal domain zf-RING_4 PF14570.1 EXF76070.1 - 0.01 15.4 3.5 0.026 14.0 2.4 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 EXF76070.1 - 0.012 15.3 1.7 0.022 14.4 1.2 1.5 1 1 0 1 1 1 0 zinc-RING finger domain tRNA_NucTran2_2 PF13735.1 EXF76070.1 - 0.069 12.9 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 tRNA nucleotidyltransferase domain 2 putative zf-Di19 PF05605.7 EXF76070.1 - 0.086 12.9 2.2 9.4 6.4 0.3 2.6 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding Tmpp129 PF10272.4 EXF76070.1 - 0.15 10.7 0.9 0.56 8.8 0.2 2.0 2 0 0 2 2 2 0 Putative transmembrane protein precursor zf-RING_3 PF14369.1 EXF76070.1 - 0.21 11.5 1.5 1.6 8.8 0.0 2.5 2 0 0 2 2 2 0 zinc-finger zf-RING_UBOX PF13445.1 EXF76070.1 - 0.52 10.0 5.0 2.2 8.0 0.2 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-UDP PF14569.1 EXF76070.1 - 0.71 9.6 3.1 3.3 7.5 2.1 2.0 1 1 1 2 2 2 0 Zinc-binding RING-finger DUF723 PF05265.8 EXF76070.1 - 1.1 9.1 3.2 0.7 9.7 0.3 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF723) Pheromone PF08015.6 EXF76070.1 - 1.1 10.0 9.3 2.1 9.2 1.1 2.4 2 0 0 2 2 2 0 Fungal mating-type pheromone Pkinase PF00069.20 EXF76072.1 - 3.6e-49 167.2 0.0 5.2e-49 166.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF76072.1 - 7.9e-27 93.9 0.0 1.2e-26 93.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF76072.1 - 0.00012 21.1 0.0 0.00019 20.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EXF76072.1 - 0.0074 16.0 0.3 0.0074 16.0 0.2 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EXF76072.1 - 0.031 13.3 0.0 0.058 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAP1 PF08601.5 EXF76073.1 - 2.5e-55 188.5 11.1 2.5e-55 188.5 7.7 2.8 1 1 1 2 2 1 1 Transcription factor PAP1 bZIP_1 PF00170.16 EXF76073.1 - 2.2e-11 43.5 10.5 5.4e-11 42.2 7.3 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EXF76073.1 - 0.0014 18.3 11.9 0.01 15.6 8.3 2.2 1 1 0 1 1 1 1 Basic region leucine zipper DUF904 PF06005.7 EXF76073.1 - 0.0025 18.0 2.8 0.0064 16.7 2.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF904) DUF812 PF05667.6 EXF76073.1 - 0.0037 15.8 6.7 0.0065 15.0 4.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF812) GAS PF13851.1 EXF76073.1 - 0.0085 15.3 6.4 0.016 14.4 4.4 1.3 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding DUF972 PF06156.8 EXF76073.1 - 0.015 15.6 1.0 0.049 13.9 0.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF972) APG6 PF04111.7 EXF76073.1 - 0.023 13.7 1.9 0.043 12.8 1.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Med30 PF11315.3 EXF76073.1 - 0.024 14.7 1.2 8.3 6.5 0.7 2.4 2 0 0 2 2 2 0 Mediator complex subunit 30 Adeno_PIX PF03955.9 EXF76073.1 - 0.024 15.1 1.3 0.024 15.1 0.9 2.5 3 0 0 3 3 1 0 Adenovirus hexon-associated protein (IX) SlyX PF04102.7 EXF76073.1 - 0.031 14.6 0.6 0.031 14.6 0.4 2.1 2 0 0 2 2 2 0 SlyX Prominin PF05478.6 EXF76073.1 - 0.034 11.6 0.6 0.054 11.0 0.4 1.2 1 0 0 1 1 1 0 Prominin NPV_P10 PF05531.7 EXF76073.1 - 0.04 14.1 0.8 0.04 14.1 0.6 1.9 2 0 0 2 2 1 0 Nucleopolyhedrovirus P10 protein Herpes_UL6 PF01763.11 EXF76073.1 - 0.053 11.7 1.7 0.081 11.0 1.2 1.2 1 0 0 1 1 1 0 Herpesvirus UL6 like IncA PF04156.9 EXF76073.1 - 0.057 13.0 4.7 0.1 12.1 3.3 1.3 1 0 0 1 1 1 0 IncA protein WXG100 PF06013.7 EXF76073.1 - 0.06 13.3 2.4 0.41 10.6 0.1 2.5 2 0 0 2 2 2 0 Proteins of 100 residues with WXG V_ATPase_I PF01496.14 EXF76073.1 - 0.097 10.5 0.8 0.14 10.0 0.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DOG1 PF14144.1 EXF76073.1 - 0.1 12.6 0.2 0.29 11.1 0.1 1.7 1 0 0 1 1 1 0 Seed dormancy control TMF_DNA_bd PF12329.3 EXF76073.1 - 0.15 11.8 9.1 0.36 10.6 6.3 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 EXF76073.1 - 0.16 11.4 3.4 0.43 10.0 2.4 1.7 1 0 0 1 1 1 0 Septum formation initiator ACCA PF03255.9 EXF76073.1 - 0.22 11.0 2.0 0.42 10.1 1.4 1.4 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Glutaredoxin2_C PF04399.8 EXF76073.1 - 0.27 10.8 2.5 0.56 9.7 1.7 1.5 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain FlaC_arch PF05377.6 EXF76073.1 - 0.28 11.0 2.0 0.54 10.1 1.4 1.5 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Jnk-SapK_ap_N PF09744.4 EXF76073.1 - 0.77 9.7 7.1 1.4 8.8 4.9 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 bZIP_Maf PF03131.12 EXF76073.1 - 1.1 9.6 11.5 0.32 11.3 5.8 1.7 2 0 0 2 2 1 0 bZIP Maf transcription factor Rb_C PF08934.5 EXF76073.1 - 1.2 8.7 11.0 0.87 9.2 1.2 2.6 2 0 0 2 2 2 0 Rb C-terminal domain Snapin_Pallidin PF14712.1 EXF76073.1 - 1.7 9.0 6.5 0.62 10.4 0.8 2.3 2 0 0 2 2 2 0 Snapin/Pallidin Cluap1 PF10234.4 EXF76073.1 - 3.2 6.8 9.3 1 8.4 4.5 1.4 2 0 0 2 2 1 0 Clusterin-associated protein-1 CDC45 PF02724.9 EXF76073.1 - 5.9 4.8 11.6 8.6 4.2 8.1 1.1 1 0 0 1 1 1 0 CDC45-like protein BSD PF03909.12 EXF76074.1 - 4.7e-16 58.2 0.1 1e-15 57.1 0.1 1.6 1 0 0 1 1 1 1 BSD domain Sigma70_r2 PF04542.9 EXF76074.1 - 0.0092 15.5 0.4 0.022 14.3 0.0 1.8 2 0 0 2 2 2 1 Sigma-70 region 2 WGG PF10273.4 EXF76075.1 - 9.3e-26 89.7 0.1 9.3e-26 89.7 0.1 1.6 2 0 0 2 2 2 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 EXF76075.1 - 0.0074 16.3 2.4 0.0085 16.1 0.2 2.0 1 1 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) Abhydrolase_3 PF07859.8 EXF76076.1 - 4e-41 140.9 0.0 1.2e-31 109.9 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF2424 PF10340.4 EXF76076.1 - 3e-14 52.4 0.0 5.1e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EXF76076.1 - 0.00017 21.3 0.0 0.00037 20.2 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EXF76076.1 - 0.00038 19.3 0.2 0.042 12.5 0.0 2.3 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_6 PF12697.2 EXF76076.1 - 0.0014 18.5 0.0 0.0031 17.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family MRP-L27 PF09809.4 EXF76077.1 - 1.7e-17 63.0 0.3 2.8e-17 62.3 0.2 1.3 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L27 THOC7 PF05615.8 EXF76078.1 - 0.0056 16.9 2.1 0.0067 16.6 1.5 1.2 1 0 0 1 1 1 1 Tho complex subunit 7 MAT1 PF06391.8 EXF76078.1 - 0.015 14.9 2.7 0.019 14.5 1.9 1.2 1 0 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 TBCA PF02970.11 EXF76078.1 - 0.062 13.3 1.0 0.18 11.8 0.5 1.9 2 0 0 2 2 2 0 Tubulin binding cofactor A ComX PF05952.7 EXF76078.1 - 0.095 12.2 2.1 0.15 11.5 0.1 2.3 3 0 0 3 3 3 0 Bacillus competence pheromone ComX Cep57_MT_bd PF06657.8 EXF76078.1 - 0.29 11.0 3.3 0.47 10.4 0.2 2.3 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF4200 PF13863.1 EXF76078.1 - 0.36 10.7 9.1 0.24 11.3 5.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF972 PF06156.8 EXF76078.1 - 1.5 9.2 6.0 6.2 7.2 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) RNase_H PF00075.19 EXF76079.1 - 7.3e-06 26.3 0.5 1.8e-05 25.1 0.1 1.8 2 1 0 2 2 2 1 RNase H RVT_3 PF13456.1 EXF76079.1 - 0.00044 19.9 0.0 0.095 12.4 0.0 2.5 1 1 1 2 2 2 2 Reverse transcriptase-like Peptidase_S8 PF00082.17 EXF76080.1 - 1.5e-45 155.5 0.4 2.7e-45 154.6 0.3 1.4 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EXF76080.1 - 1.1e-06 29.0 0.0 5.7e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) Inhibitor_I9 PF05922.11 EXF76080.1 - 0.017 15.6 0.1 0.071 13.6 0.0 2.1 2 0 0 2 2 2 0 Peptidase inhibitor I9 Alpha-amylase PF00128.19 EXF76081.1 - 1.8e-24 86.7 2.3 3.7e-21 75.8 0.8 2.8 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Glyco_transf_5 PF08323.6 EXF76081.1 - 1.1e-16 61.0 0.6 1.8e-16 60.3 0.4 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EXF76081.1 - 1.9e-07 30.6 0.0 3.6e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EXF76081.1 - 3.2e-07 30.5 0.0 8.3e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Alpha-amylase PF00128.19 EXF76082.1 - 1.7e-60 205.0 0.9 2.5e-60 204.5 0.6 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EXF76082.1 - 3.1e-21 75.2 0.3 6.1e-21 74.3 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Fungal_trans PF04082.13 EXF76083.1 - 4.1e-13 48.8 0.9 4.1e-13 48.8 0.6 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EXF76083.1 - 5.8e-11 42.0 11.3 4.8e-05 23.4 0.1 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type Zn_clus PF00172.13 EXF76083.1 - 6.5e-07 29.1 11.0 6.5e-07 29.1 7.6 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 EXF76083.1 - 1.8e-05 24.7 20.8 0.00028 20.9 0.1 3.8 4 0 0 4 4 4 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EXF76083.1 - 0.00015 21.8 5.4 0.00055 20.1 0.1 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-met PF12874.2 EXF76083.1 - 0.67 10.2 7.1 4.7 7.5 0.7 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EXF76083.1 - 2.7 8.2 13.2 0.83 9.8 0.2 3.4 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-H2C2_5 PF13909.1 EXF76083.1 - 6.9 7.1 7.6 3.5 8.0 3.1 2.3 2 0 0 2 2 2 0 C2H2-type zinc-finger domain MFS_1 PF07690.11 EXF76085.1 - 4.2e-35 121.1 37.9 1.2e-34 119.6 22.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF76085.1 - 3e-16 59.0 7.5 3e-16 59.0 5.2 3.0 2 1 0 2 2 2 1 Sugar (and other) transporter Fzo_mitofusin PF04799.8 EXF76085.1 - 0.21 10.9 0.2 0.39 10.0 0.1 1.3 1 0 0 1 1 1 0 fzo-like conserved region Fungal_trans PF04082.13 EXF76086.1 - 1.6e-11 43.5 0.0 2.4e-11 43.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF76086.1 - 1.7e-06 27.8 10.3 3.3e-06 26.8 7.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3395 PF11875.3 EXF76087.1 - 1.2e-24 86.7 0.0 2e-24 85.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 EXF76087.1 - 3.5e-09 36.2 0.1 6e-09 35.5 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Fungal_trans PF04082.13 EXF76089.1 - 5.5e-25 87.7 0.0 9.7e-25 86.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF76089.1 - 3.1e-08 33.3 13.0 3.1e-08 33.3 9.0 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Med3 PF11593.3 EXF76089.1 - 2.8 7.1 8.4 7.2 5.7 5.8 1.6 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RVT_1 PF00078.22 EXF76091.1 - 5.4e-24 84.7 0.0 1.7e-23 83.1 0.0 1.7 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EXF76091.1 - 1.9e-05 24.2 1.0 0.00012 21.6 0.2 2.6 2 1 0 2 2 2 1 Endonuclease-reverse transcriptase Med17 PF10156.4 EXF76092.1 - 2e-80 270.3 0.0 2.8e-80 269.8 0.0 1.1 1 0 0 1 1 1 1 Subunit 17 of Mediator complex SNF2_N PF00176.18 EXF76093.1 - 2.1e-68 230.2 0.6 3.3e-68 229.6 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EXF76093.1 - 3.4e-11 42.8 0.1 2.1e-10 40.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EXF76093.1 - 8.1e-08 31.7 5.1 1.6e-07 30.8 3.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EXF76093.1 - 8.3e-08 31.9 5.1 1.6e-07 31.0 3.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EXF76093.1 - 2.2e-06 27.5 5.2 4.2e-06 26.6 3.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 EXF76093.1 - 9.4e-06 25.5 0.4 6.4e-05 22.8 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.1 EXF76093.1 - 1.2e-05 24.8 3.2 2.3e-05 23.9 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.24 EXF76093.1 - 1.3e-05 24.7 0.6 5.2e-05 22.7 0.4 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-C3HC4_4 PF15227.1 EXF76093.1 - 6.2e-05 22.7 5.6 0.00015 21.5 3.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EXF76093.1 - 0.00011 21.8 2.0 0.00027 20.6 1.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EXF76093.1 - 0.00019 21.0 4.2 0.00035 20.2 2.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EXF76093.1 - 1.9 8.1 4.6 5.2 6.7 3.2 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain ketoacyl-synt PF00109.21 EXF76094.1 - 2.9e-79 266.1 0.1 6.3e-79 265.0 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EXF76094.1 - 9.9e-61 205.7 0.0 1.7e-60 205.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EXF76094.1 - 3.2e-48 164.4 0.0 5.5e-48 163.6 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EXF76094.1 - 1.4e-44 151.9 3.5 1.5e-44 151.8 1.0 2.2 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EXF76094.1 - 4.3e-37 127.6 2.6 1.5e-36 125.8 1.8 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EXF76094.1 - 3.1e-34 117.3 0.2 1.3e-33 115.3 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EXF76094.1 - 4.3e-05 23.0 0.3 0.00023 20.7 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF76094.1 - 6e-05 22.7 0.3 0.00015 21.5 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 EXF76094.1 - 0.00096 18.2 0.1 0.0026 16.8 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain NAD_binding_3 PF03447.11 EXF76094.1 - 0.036 14.4 0.1 3.5 8.0 0.1 3.3 3 0 0 3 3 3 0 Homoserine dehydrogenase, NAD binding domain MFS_1 PF07690.11 EXF76095.1 - 1.1e-27 96.6 46.2 4.4e-26 91.4 31.3 3.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EXF76095.1 - 7.2e-07 27.7 15.0 1.1e-06 27.1 10.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) HET PF06985.6 EXF76096.1 - 1e-19 71.0 4.7 3.8e-16 59.4 0.2 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) RRM_1 PF00076.17 EXF76097.1 - 2.4e-14 52.6 0.0 4.4e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF76097.1 - 7.1e-13 48.3 0.0 1.1e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF76097.1 - 3.4e-05 23.5 0.0 5.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Asp-B-Hydro_N PF05279.6 EXF76097.1 - 1.5 8.5 23.8 2.4 7.9 16.5 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SAPS PF04499.10 EXF76097.1 - 3.3 6.2 8.4 4.8 5.7 5.8 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Borrelia_P83 PF05262.6 EXF76097.1 - 9.1 4.4 22.4 12 4.0 15.5 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2413 PF10310.4 EXF76097.1 - 9.3 4.9 24.4 16 4.1 16.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) SOBP PF15279.1 EXF76097.1 - 9.5 6.5 11.1 15 5.8 7.7 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein GTP_EFTU PF00009.22 EXF76098.1 - 2.9e-54 183.3 0.0 4.6e-54 182.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EXF76098.1 - 1e-15 57.3 0.0 2.4e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EXF76098.1 - 8.7e-08 31.9 0.0 1.9e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EXF76098.1 - 4.1e-07 30.0 0.0 1.2e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EXF76098.1 - 3.8e-06 26.4 0.0 0.00022 20.7 0.0 2.9 3 0 0 3 3 3 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 EXF76098.1 - 0.0067 16.3 0.0 0.015 15.2 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Paf67 PF10255.4 EXF76099.1 - 8.2e-153 509.0 0.9 9.8e-153 508.7 0.6 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TPR_2 PF07719.12 EXF76099.1 - 0.016 15.0 0.0 0.089 12.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EXF76099.1 - 0.057 13.0 0.0 0.29 10.8 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EXF76099.1 - 0.087 12.7 0.0 0.69 9.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Usp PF00582.21 EXF76101.1 - 9e-15 55.0 0.9 1.7e-14 54.2 0.0 1.9 2 0 0 2 2 2 1 Universal stress protein family DUF3326 PF11805.3 EXF76101.1 - 0.063 11.9 0.3 0.098 11.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3326) NKWYS PF10364.4 EXF76101.1 - 0.069 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein ABA_GPCR PF12430.3 EXF76103.1 - 3.1e-54 183.1 0.0 3.8e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor M20_dimer PF07687.9 EXF76104.1 - 8.9e-07 28.6 0.0 1.8e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EXF76104.1 - 4.4e-06 26.3 3.3 8.2e-06 25.4 2.3 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 MFS_1 PF07690.11 EXF76106.1 - 6.1e-32 110.6 34.5 8e-32 110.3 23.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 EXF76106.1 - 0.044 14.1 0.4 0.13 12.6 0.3 1.8 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CaATP_NAI PF12515.3 EXF76106.1 - 0.19 11.2 0.2 0.37 10.3 0.2 1.4 1 0 0 1 1 1 0 Ca2+-ATPase N terminal autoinhibitory domain Lipase_GDSL_2 PF13472.1 EXF76107.1 - 1.1e-16 61.4 0.0 1.4e-16 61.1 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EXF76107.1 - 5.5e-15 55.8 0.0 6.6e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase F-box-like PF12937.2 EXF76109.1 - 5.9e-05 22.7 0.1 0.00019 21.1 0.1 1.9 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EXF76109.1 - 0.14 11.8 1.0 1.2 8.8 0.1 2.4 2 0 0 2 2 2 0 F-box domain Zn_clus PF00172.13 EXF76110.1 - 1.5e-08 34.3 8.2 3.3e-08 33.3 5.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain F-box-like PF12937.2 EXF76111.1 - 0.009 15.7 1.6 0.0092 15.6 0.0 1.8 2 0 0 2 2 2 1 F-box-like Ribosomal_S10 PF00338.17 EXF76111.1 - 0.05 13.4 0.1 0.21 11.4 0.1 2.0 3 0 0 3 3 3 0 Ribosomal protein S10p/S20e F-box PF00646.28 EXF76111.1 - 0.62 9.7 0.0 0.62 9.7 0.0 2.6 3 1 1 4 4 4 0 F-box domain DZR PF12773.2 EXF76111.1 - 1.2 8.9 6.0 21 5.0 1.0 3.0 2 1 0 2 2 2 0 Double zinc ribbon PALP PF00291.20 EXF76113.1 - 3.9e-32 111.6 0.2 4.8e-32 111.4 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LYTB PF02401.13 EXF76113.1 - 0.0027 16.6 0.0 0.005 15.8 0.0 1.4 1 0 0 1 1 1 1 LytB protein TauD PF02668.11 EXF76114.1 - 1e-26 94.1 0.2 1.3e-26 93.8 0.1 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TilS PF09179.6 EXF76114.1 - 0.11 12.4 2.6 17 5.5 0.1 3.2 3 0 0 3 3 3 0 TilS substrate binding domain DUF917 PF06032.7 EXF76115.1 - 1.8e-105 352.3 0.9 1.8e-105 352.3 0.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EXF76115.1 - 6.2e-50 169.9 12.8 6.8e-50 169.8 3.0 3.6 3 1 0 3 3 3 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EXF76115.1 - 9.9e-33 113.1 0.1 7.2e-30 103.7 0.0 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region StbA PF06406.6 EXF76115.1 - 0.0071 15.3 0.3 3.3 6.5 0.0 2.8 2 1 1 3 3 3 2 StbA protein MutL PF13941.1 EXF76115.1 - 0.0085 14.4 5.3 0.044 12.1 0.0 2.7 3 0 0 3 3 3 2 MutL protein Transp_cyt_pur PF02133.10 EXF76116.1 - 6.7e-91 305.0 36.7 7.9e-91 304.8 25.4 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin HNH_2 PF13391.1 EXF76117.1 - 1.2e-07 31.3 0.0 6e-07 29.1 0.0 2.2 2 1 0 2 2 2 1 HNH endonuclease DUF2764 PF10962.3 EXF76117.1 - 0.069 12.3 0.3 0.21 10.8 0.0 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2764) DUF3387 PF11867.3 EXF76117.1 - 0.14 11.1 0.2 0.35 9.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) DUF3275 PF11679.3 EXF76117.1 - 0.97 9.0 3.1 3.2 7.3 2.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3275) Fungal_trans PF04082.13 EXF76118.1 - 2.9e-33 114.8 0.1 4.3e-33 114.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_2 PF04909.9 EXF76119.1 - 2.6e-34 119.0 0.4 4.5e-34 118.2 0.3 1.4 1 0 0 1 1 1 1 Amidohydrolase FAD_binding_4 PF01565.18 EXF76121.1 - 1e-15 57.4 1.0 2.8e-15 55.9 0.7 1.7 2 0 0 2 2 2 1 FAD binding domain Strep_SA_rep PF06696.6 EXF76122.1 - 0.0051 16.5 2.0 0.01 15.5 1.4 1.5 1 0 0 1 1 1 1 Streptococcal surface antigen repeat AAA PF00004.24 EXF76123.1 - 4.2e-10 39.9 1.0 5.7e-10 39.4 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EXF76123.1 - 0.0085 16.0 0.2 0.5 10.3 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.1 EXF76123.1 - 0.037 14.3 1.3 0.75 10.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EXF76123.1 - 0.068 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EXF76123.1 - 0.17 10.5 0.1 0.26 9.9 0.1 1.2 1 0 0 1 1 1 0 TIP49 C-terminus Phage_Gp19 PF09355.5 EXF76124.1 - 0.17 11.7 0.9 0.56 10.0 0.0 2.3 3 0 0 3 3 3 0 Phage protein Gp19/Gp15/Gp42 Peptidase_M43 PF05572.8 EXF76125.1 - 1.6e-14 53.8 1.3 1.4e-13 50.7 0.1 2.3 2 1 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EXF76125.1 - 4.9e-05 23.3 1.3 7.4e-05 22.7 0.9 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EXF76125.1 - 6.3e-05 23.1 2.4 9.1e-05 22.5 1.5 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EXF76125.1 - 7.2e-05 22.3 0.1 0.00013 21.5 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EXF76125.1 - 0.0069 16.1 0.0 0.0081 15.8 0.0 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_3 PF13582.1 EXF76125.1 - 0.019 15.4 0.9 0.039 14.4 0.6 1.7 1 1 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EXF76125.1 - 0.3 9.9 3.1 0.2 10.4 0.8 1.6 2 0 0 2 2 2 0 Peptidase M66 FAD_binding_3 PF01494.14 EXF76126.1 - 1.1e-21 77.3 0.1 1.6e-20 73.4 0.1 2.3 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF76126.1 - 0.0009 18.2 0.5 1.2 7.9 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EXF76126.1 - 0.001 18.2 0.7 0.044 12.8 0.0 2.3 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EXF76126.1 - 0.0071 15.3 0.3 1.3 7.8 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 EXF76126.1 - 0.0085 16.1 0.1 0.03 14.3 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EXF76126.1 - 0.024 13.2 0.3 0.44 9.1 0.0 2.5 3 0 0 3 3 3 0 Tryptophan halogenase Glyco_hydro_43 PF04616.9 EXF76127.1 - 6.4e-31 107.4 0.4 1e-30 106.8 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Acetyltransf_1 PF00583.19 EXF76129.1 - 2.8e-08 33.6 0.0 4.4e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF76129.1 - 3.9e-05 23.7 0.0 6.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EXF76129.1 - 0.048 13.6 0.0 0.091 12.7 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EXF76129.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain EF-hand_4 PF12763.2 EXF76130.1 - 0.0067 16.1 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Peptidase_C53 PF05550.6 EXF76130.1 - 0.12 11.8 0.1 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Pestivirus Npro endopeptidase C53 MAP65_ASE1 PF03999.7 EXF76131.1 - 1.7e-70 238.4 15.2 1.7e-70 238.4 10.5 2.7 2 1 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) AAA_13 PF13166.1 EXF76131.1 - 0.0016 16.9 4.3 0.0029 16.1 3.0 1.3 1 0 0 1 1 1 1 AAA domain Spectrin PF00435.16 EXF76131.1 - 0.022 15.0 1.7 0.022 15.0 1.2 4.2 3 1 1 4 4 4 0 Spectrin repeat Baculo_PEP_C PF04513.7 EXF76131.1 - 0.56 10.0 1.8 5 6.9 0.4 2.8 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.6 EXF76131.1 - 0.81 9.5 5.6 2.5 8.0 0.8 3.1 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Sipho_Gp157 PF05565.6 EXF76131.1 - 2.4 7.7 9.1 0.097 12.2 0.3 2.6 2 1 0 2 2 2 0 Siphovirus Gp157 Polysacc_lyase PF14099.1 EXF76132.1 - 2.7e-46 158.0 5.7 3.2e-46 157.7 3.9 1.0 1 0 0 1 1 1 1 Polysaccharide lyase DUF342 PF03961.8 EXF76133.1 - 0.024 13.0 0.0 0.049 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) UDPG_MGDP_dh_N PF03721.9 EXF76134.1 - 1.1e-25 90.1 0.1 5.8e-18 64.9 0.0 2.2 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 EXF76134.1 - 3.5e-18 65.6 0.0 7.7e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.10 EXF76134.1 - 1.9e-06 27.7 0.0 3.5e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_18 PF12847.2 EXF76134.1 - 0.0016 18.9 0.0 0.0071 16.9 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain TrkA_N PF02254.13 EXF76134.1 - 0.0017 18.3 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.12 EXF76134.1 - 0.038 14.4 0.0 0.32 11.4 0.0 2.4 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EXF76134.1 - 0.041 13.5 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Chitin_synth_2 PF03142.10 EXF76135.1 - 2.8e-27 95.3 0.3 9.1e-23 80.4 0.2 2.4 1 1 1 2 2 2 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EXF76135.1 - 1.7e-11 44.3 0.1 3e-11 43.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EXF76135.1 - 6.5e-11 42.3 1.2 1.4e-10 41.1 0.9 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EXF76135.1 - 0.0002 21.0 0.1 0.15 11.7 0.0 3.1 3 0 0 3 3 3 2 Glycosyl transferase family 2 HET PF06985.6 EXF76140.1 - 3.8e-33 114.5 0.1 5.7e-33 114.0 0.1 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MBD PF01429.14 EXF76140.1 - 0.19 11.3 1.2 2.3 7.7 0.0 2.8 3 0 0 3 3 3 0 Methyl-CpG binding domain V4R PF02830.13 EXF76141.1 - 0.002 17.8 18.5 8 6.3 1.1 5.3 4 1 1 5 5 5 5 V4R domain Phage_Coat_B PF05356.6 EXF76141.1 - 2.8 7.7 7.0 0.92 9.2 1.7 2.4 2 1 1 3 3 3 0 Phage Coat protein B Asparaginase_2 PF01112.13 EXF76142.1 - 1.6e-53 181.5 8.2 9.7e-43 146.0 3.9 3.1 2 1 0 2 2 2 2 Asparaginase DUF3325 PF11804.3 EXF76143.1 - 0.058 13.3 0.0 0.075 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3325) DUF2140 PF09911.4 EXF76143.1 - 0.059 12.5 0.0 0.081 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) AAA_18 PF13238.1 EXF76145.1 - 7.4e-08 32.7 0.0 1.3e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EXF76145.1 - 5.6e-05 23.9 0.0 8.9e-05 23.2 0.0 1.4 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 EXF76145.1 - 0.00013 21.6 0.0 0.019 14.6 0.0 2.2 2 0 0 2 2 2 2 Chloramphenicol phosphotransferase-like protein AAA_33 PF13671.1 EXF76145.1 - 0.00022 21.0 0.0 0.00033 20.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EXF76145.1 - 0.0012 18.1 0.0 0.003 16.8 0.0 1.6 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA PF00004.24 EXF76145.1 - 0.037 14.2 0.0 0.21 11.7 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 EXF76145.1 - 0.04 13.5 0.0 0.11 12.1 0.0 1.7 1 1 1 2 2 2 0 Adenylylsulphate kinase Sigma54_activ_2 PF14532.1 EXF76145.1 - 0.091 12.8 0.0 0.22 11.5 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain Cytidylate_kin2 PF13189.1 EXF76145.1 - 0.11 12.3 0.0 0.21 11.4 0.0 1.6 1 1 0 1 1 1 0 Cytidylate kinase-like family tRNA-synt_2 PF00152.15 EXF76146.1 - 1e-18 67.2 0.0 1.4e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EXF76146.1 - 0.0088 15.2 0.0 3.5 6.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Toxin_37 PF11415.3 EXF76146.1 - 0.019 14.5 0.8 0.049 13.2 0.2 1.9 2 0 0 2 2 2 0 Antifungal peptide termicin DUF3328 PF11807.3 EXF76147.1 - 7.1e-28 97.7 0.1 9.5e-28 97.3 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) FAD_binding_3 PF01494.14 EXF76148.1 - 1e-14 54.4 0.0 1.5e-07 30.8 0.0 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EXF76148.1 - 3.3e-06 27.0 0.0 8.5e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EXF76148.1 - 0.0016 18.8 0.0 0.0051 17.1 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF76148.1 - 0.0049 15.8 0.1 0.019 13.8 0.0 1.7 1 1 1 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EXF76148.1 - 0.0094 15.0 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EXF76148.1 - 0.011 14.6 0.1 0.019 13.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EXF76148.1 - 0.047 13.7 0.0 0.095 12.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_Gly3P_dh_N PF01210.18 EXF76148.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 EXF76148.1 - 0.11 12.4 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain Peptidase_M43 PF05572.8 EXF76150.1 - 6.1e-15 55.1 0.1 8.5e-15 54.6 0.0 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 EXF76150.1 - 4.6e-05 23.5 1.7 7e-05 22.9 1.2 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EXF76150.1 - 8e-05 22.2 0.1 0.00016 21.2 0.1 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EXF76150.1 - 0.001 19.0 1.7 0.0021 18.0 1.2 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EXF76150.1 - 0.0011 19.4 0.8 0.005 17.3 0.5 2.0 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.3 EXF76150.1 - 0.0049 15.3 0.3 0.0074 14.7 0.2 1.1 1 0 0 1 1 1 1 Putative peptidase family Peptidase_M10 PF00413.19 EXF76150.1 - 0.015 15.0 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Matrixin Peptidase_M66 PF10462.4 EXF76150.1 - 0.042 12.7 0.1 0.066 12.0 0.0 1.2 1 0 0 1 1 1 0 Peptidase M66 Peptidase_M7 PF02031.11 EXF76150.1 - 0.055 13.1 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family DUF3455 PF11937.3 EXF76151.1 - 3.8e-29 101.9 0.1 5e-29 101.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) Pkinase PF00069.20 EXF76152.1 - 8.7e-72 241.3 0.0 1e-71 241.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF76152.1 - 2.5e-31 108.7 0.0 3.5e-31 108.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EXF76152.1 - 0.019 14.7 0.1 0.069 12.8 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EXF76152.1 - 0.087 11.8 0.1 0.25 10.3 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LMWPc PF01451.16 EXF76153.1 - 2.7e-36 124.9 0.0 3.1e-36 124.7 0.0 1.0 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase CFEM PF05730.6 EXF76154.1 - 6.6e-11 41.8 12.3 1.1e-10 41.2 8.5 1.3 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.15 EXF76154.1 - 2.6 8.1 5.8 0.94 9.5 1.3 2.1 2 0 0 2 2 2 0 Gamma-thionin family Sporozoite_P67 PF05642.6 EXF76154.1 - 8.6 4.0 9.8 8.7 4.0 6.8 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen 4HBT_2 PF13279.1 EXF76155.1 - 2e-06 28.2 0.0 3.3e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Thioesterase-like superfamily Ank_2 PF12796.2 EXF76156.1 - 2.8e-18 66.0 0.0 1.3e-09 38.2 0.0 6.2 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank PF00023.25 EXF76156.1 - 4.7e-18 64.0 0.1 6.4e-08 32.0 0.0 6.0 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 EXF76156.1 - 1.5e-11 44.1 0.2 0.005 17.0 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EXF76156.1 - 6.1e-11 42.5 1.0 8.4e-05 22.9 0.0 5.7 3 1 3 6 6 6 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF76156.1 - 6.8e-11 41.3 3.2 7.9e-05 22.5 0.0 6.4 7 0 0 7 7 5 1 Ankyrin repeat NACHT PF05729.7 EXF76156.1 - 0.00019 21.1 0.0 0.00057 19.5 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EXF76156.1 - 0.00021 21.4 0.0 0.00061 19.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EXF76156.1 - 0.0028 17.6 0.0 0.013 15.4 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 EXF76156.1 - 0.0031 17.6 0.0 0.0095 16.0 0.0 1.9 1 0 0 1 1 1 1 RNA helicase APS_kinase PF01583.15 EXF76156.1 - 0.0035 17.0 0.0 0.0065 16.1 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_17 PF13207.1 EXF76156.1 - 0.0036 18.1 0.0 0.017 15.9 0.0 2.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EXF76156.1 - 0.0044 17.3 0.0 0.017 15.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EXF76156.1 - 0.014 15.1 0.0 0.029 14.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.10 EXF76156.1 - 0.014 15.1 0.1 0.043 13.5 0.0 1.8 2 0 0 2 2 2 0 NTPase AAA_33 PF13671.1 EXF76156.1 - 0.019 14.8 0.0 0.047 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EXF76156.1 - 0.023 13.9 0.0 0.042 13.0 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MMR_HSR1 PF01926.18 EXF76156.1 - 0.032 14.1 0.0 0.079 12.9 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.1 EXF76156.1 - 0.072 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EXF76156.1 - 0.075 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA PF00004.24 EXF76156.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ArabFuran-catal PF09206.6 EXF76157.1 - 1.9e-162 539.7 21.4 2.9e-162 539.1 14.8 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B, catalytic AbfB PF05270.8 EXF76157.1 - 1.6e-60 202.9 5.7 2.6e-60 202.2 3.9 1.3 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase B (ABFB) GPI-anchored PF10342.4 EXF76157.1 - 0.033 14.6 2.3 0.093 13.2 1.6 1.8 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family MBOAT_2 PF13813.1 EXF76158.1 - 3.9e-08 33.2 5.6 1e-07 31.9 3.9 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Acetyltransf_7 PF13508.1 EXF76159.1 - 5.8e-11 42.4 0.0 2.6e-10 40.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EXF76159.1 - 3.7e-10 39.7 0.0 1.3e-09 37.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EXF76159.1 - 1.5e-08 34.5 0.1 8.5e-08 32.1 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EXF76159.1 - 6.5e-08 32.7 0.0 2.2e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EXF76159.1 - 8.2e-07 28.6 0.0 1.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EXF76159.1 - 0.0022 17.8 0.0 0.0058 16.4 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase DUF929 PF06053.6 EXF76159.1 - 0.17 10.9 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF929) SnoaL_2 PF12680.2 EXF76162.1 - 5.6e-06 26.6 0.0 8.5e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EXF76162.1 - 0.0017 17.9 0.0 0.2 11.2 0.0 2.2 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase LEH PF07858.7 EXF76162.1 - 0.026 14.5 0.0 0.032 14.2 0.0 1.1 1 0 0 1 1 1 0 Limonene-1,2-epoxide hydrolase catalytic domain O-FucT PF10250.4 EXF76163.1 - 4.4e-06 26.0 0.0 0.0053 15.9 0.0 3.1 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Glyco_hydro_18 PF00704.23 EXF76165.1 - 1.6e-65 221.8 3.7 2.6e-65 221.1 2.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DNase_NucA_NucB PF14040.1 EXF76165.1 - 0.0012 18.9 0.0 1.7 8.8 0.0 3.2 3 0 0 3 3 3 2 Deoxyribonuclease NucA/NucB LysM PF01476.15 EXF76166.1 - 1.6e-09 37.4 6.6 0.25 11.2 0.0 6.9 7 0 0 7 7 7 3 LysM domain HTH_Tnp_1 PF01527.15 EXF76166.1 - 0.052 13.5 0.1 1.8e+02 2.1 0.0 4.3 5 0 0 5 5 5 0 Transposase CENP-H PF05837.7 EXF76167.1 - 2.6 8.2 8.2 4.7 7.4 1.0 2.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) MFS_1 PF07690.11 EXF76168.1 - 2.7e-38 131.6 29.9 2.7e-38 131.6 20.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF76168.1 - 1.8e-13 49.9 12.1 1.8e-13 49.9 8.4 2.4 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EXF76168.1 - 5.8e-09 34.6 2.4 5.8e-09 34.6 1.7 1.9 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) BT1 PF03092.11 EXF76168.1 - 0.0047 15.7 0.5 0.0047 15.7 0.3 2.2 3 0 0 3 3 3 1 BT1 family Alpha_E2_glycop PF00943.14 EXF76168.1 - 0.012 14.2 0.6 0.019 13.6 0.4 1.1 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein DUF4381 PF14316.1 EXF76168.1 - 0.47 10.5 3.8 3.6 7.6 0.3 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) FAD_binding_3 PF01494.14 EXF76169.1 - 8.4e-19 67.8 0.0 1.1e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF76169.1 - 5.5e-10 38.6 0.8 0.00028 19.9 0.6 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF76169.1 - 9.2e-08 32.0 3.4 1.8e-07 31.0 0.5 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EXF76169.1 - 1.3e-07 30.8 1.7 2.4e-07 29.9 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.2 EXF76169.1 - 2.9e-05 23.3 0.1 3.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF76169.1 - 3.7e-05 22.8 0.3 0.25 10.2 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein HI0933_like PF03486.9 EXF76169.1 - 6.5e-05 21.5 0.1 0.0004 18.9 0.1 1.9 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EXF76169.1 - 6.8e-05 22.8 0.6 0.00015 21.7 0.4 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF76169.1 - 0.0004 20.7 0.7 0.0027 18.0 0.7 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF76169.1 - 0.0082 15.0 0.3 0.012 14.4 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EXF76169.1 - 0.011 15.7 0.1 0.019 15.0 0.1 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF76169.1 - 0.034 13.2 0.1 0.056 12.5 0.1 1.3 1 0 0 1 1 1 0 Thi4 family FMO-like PF00743.14 EXF76169.1 - 0.08 11.1 0.2 0.11 10.6 0.1 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like 3HCDH_N PF02737.13 EXF76169.1 - 0.081 12.5 0.2 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAA_hydrolase PF01557.13 EXF76170.1 - 1.5e-59 201.1 0.0 1.8e-59 200.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Homeobox_KN PF05920.6 EXF76171.1 - 1.3e-14 53.6 2.1 4.8e-14 51.7 1.5 2.1 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EXF76171.1 - 2e-09 36.9 0.8 6.6e-09 35.2 0.6 1.9 1 0 0 1 1 1 1 Homeobox domain zf-C2H2_4 PF13894.1 EXF76171.1 - 0.0013 18.8 2.0 0.0013 18.8 1.4 5.4 5 1 0 5 5 5 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF76171.1 - 0.0071 16.6 1.6 0.0071 16.6 1.1 4.9 4 1 1 5 5 5 1 Zinc finger, C2H2 type Homez PF11569.3 EXF76171.1 - 0.012 14.6 0.4 0.044 12.8 0.3 2.0 1 1 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez HTH_Tnp_Tc5 PF03221.11 EXF76171.1 - 0.036 13.8 0.0 1.5 8.6 0.0 3.3 3 0 0 3 3 3 0 Tc5 transposase DNA-binding domain BIR PF00653.16 EXF76171.1 - 0.36 11.2 7.0 1.1 9.7 0.1 3.0 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain zf-C2H2_jaz PF12171.3 EXF76171.1 - 0.86 9.8 7.3 0.16 12.1 1.5 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PNGaseA PF12222.3 EXF76172.1 - 1.5e-124 416.1 5.3 1.8e-124 415.9 3.7 1.1 1 0 0 1 1 1 1 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A Zn_clus PF00172.13 EXF76173.1 - 4.5e-10 39.2 4.6 8.3e-10 38.4 3.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF76173.1 - 0.022 13.3 0.8 0.1 11.1 0.1 1.9 1 1 1 2 2 2 0 Fungal specific transcription factor domain BTB PF00651.26 EXF76174.1 - 0.014 15.3 0.0 0.032 14.2 0.0 1.6 1 1 0 1 1 1 0 BTB/POZ domain DAO PF01266.19 EXF76176.1 - 2.4e-24 85.9 0.0 7.5e-24 84.2 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Formyl_trans_N PF00551.14 EXF76176.1 - 1.5e-11 44.1 0.0 2.7e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Formyl transferase Pyr_redox_2 PF07992.9 EXF76176.1 - 3.7e-05 23.7 0.0 0.03 14.1 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF76176.1 - 6.3e-05 22.9 0.0 0.0002 21.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EXF76176.1 - 0.00039 19.5 0.1 0.0021 17.1 0.0 2.2 3 0 0 3 3 3 1 FAD binding domain Pyr_redox PF00070.22 EXF76176.1 - 0.0015 18.9 0.0 0.24 11.8 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EXF76176.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EXF76176.1 - 0.031 12.7 0.1 4.7 5.5 0.0 2.3 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 EXF76176.1 - 0.033 13.1 0.0 0.22 10.3 0.1 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein MFS_1 PF07690.11 EXF76177.1 - 8.7e-35 120.0 37.0 8.7e-35 120.0 25.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily GATase PF00117.23 EXF76178.1 - 7.1e-12 45.1 0.0 9.2e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EXF76178.1 - 0.0016 17.9 0.1 0.015 14.7 0.1 2.3 1 1 0 1 1 1 1 Peptidase C26 DUF4066 PF13278.1 EXF76178.1 - 0.0083 15.4 0.0 0.44 9.7 0.0 2.2 2 0 0 2 2 2 2 Putative amidotransferase CBM_1 PF00734.13 EXF76179.1 - 1.7e-12 46.7 15.5 4.3e-12 45.4 10.8 1.8 1 0 0 1 1 1 1 Fungal cellulose binding domain BNR PF02012.15 EXF76179.1 - 4.8e-07 28.6 34.8 0.46 10.5 0.2 10.1 10 0 0 10 10 10 5 BNR/Asp-box repeat Toxin_7 PF05980.7 EXF76179.1 - 0.0096 15.9 2.2 0.016 15.1 1.5 1.3 1 0 0 1 1 1 1 Toxin 7 Kelch_3 PF13415.1 EXF76179.1 - 0.033 14.3 0.1 0.033 14.3 0.1 4.7 5 0 0 5 5 5 0 Galactose oxidase, central domain Paramyxo_PNT PF13825.1 EXF76179.1 - 4.9 6.2 13.2 9.2 5.3 9.1 1.3 1 0 0 1 1 1 0 Paramyxovirus structural protein V/P N-terminus Sugar_tr PF00083.19 EXF76180.1 - 1.1e-85 287.9 27.6 1.2e-85 287.7 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF76180.1 - 5e-44 150.4 40.4 6e-37 127.1 16.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF76180.1 - 6.6e-06 24.5 4.6 6.6e-06 24.5 3.2 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Glyco_hydro_2_C PF02836.12 EXF76181.1 - 3.7e-98 328.0 0.0 5.9e-98 327.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 EXF76181.1 - 1e-54 185.4 0.0 1.8e-54 184.6 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 EXF76181.1 - 2.3e-52 176.9 0.5 3.9e-52 176.1 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EXF76181.1 - 1.2e-11 44.9 0.0 8.3e-11 42.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 Mito_carr PF00153.22 EXF76183.1 - 1.1e-40 137.2 8.5 2.3e-16 59.2 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans_2 PF11951.3 EXF76184.1 - 1.9e-19 69.5 0.1 2.9e-19 68.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_88 PF07470.8 EXF76184.1 - 0.061 12.3 0.1 0.1 11.6 0.1 1.2 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 Aminotran_4 PF01063.14 EXF76185.1 - 2.9e-20 72.7 0.0 4.9e-20 72.0 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class IV 2-Hacid_dh_C PF02826.14 EXF76186.1 - 2e-43 147.5 0.0 6.3e-43 145.9 0.0 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EXF76186.1 - 2.4e-07 30.2 0.0 3.4e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EXF76186.1 - 5.9e-06 26.2 0.0 8.6e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EXF76186.1 - 4.7e-05 23.7 0.0 8.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EXF76186.1 - 0.00015 21.5 0.0 0.00026 20.7 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EXF76186.1 - 0.0022 17.6 0.0 0.0043 16.7 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EXF76186.1 - 0.0036 16.7 0.0 0.0047 16.3 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA XdhC_C PF13478.1 EXF76186.1 - 0.0094 16.2 0.0 0.017 15.4 0.0 1.5 1 1 0 1 1 1 1 XdhC Rossmann domain Dr_adhesin PF12393.3 EXF76186.1 - 0.024 14.6 0.6 7.2 6.8 0.0 2.7 2 0 0 2 2 2 0 Dr family adhesin AlaDh_PNT_C PF01262.16 EXF76186.1 - 0.03 13.8 0.1 0.14 11.6 0.1 1.9 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 EXF76186.1 - 0.049 14.0 0.0 0.096 13.1 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF76186.1 - 0.068 13.0 0.0 0.12 12.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EXF76186.1 - 0.1 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 EXF76186.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 NADH(P)-binding TrkA_N PF02254.13 EXF76186.1 - 0.14 12.2 0.0 0.36 10.8 0.0 1.7 1 0 0 1 1 1 0 TrkA-N domain Leuk-A4-hydro_C PF09127.6 EXF76187.1 - 1.5e-35 121.9 0.0 5.1e-35 120.1 0.0 2.0 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1 PF01433.15 EXF76187.1 - 1.3e-34 120.0 0.1 2e-31 109.4 0.0 2.2 1 1 1 2 2 2 2 Peptidase family M1 Peptidase_M20 PF01546.23 EXF76187.1 - 5.3e-29 101.0 0.0 1.2e-28 99.9 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_MA_2 PF13485.1 EXF76187.1 - 9.5e-15 54.7 0.2 3.3e-14 53.0 0.1 1.9 2 0 0 2 2 2 1 Peptidase MA superfamily M20_dimer PF07687.9 EXF76187.1 - 1.6e-11 43.8 0.0 3.5e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain GCC2_GCC3 PF07699.8 EXF76187.1 - 0.097 12.2 0.2 0.23 11.0 0.1 1.6 1 0 0 1 1 1 0 GCC2 and GCC3 Tyrosinase PF00264.15 EXF76188.1 - 6e-37 127.9 2.9 1.1e-36 127.0 2.0 1.4 1 0 0 1 1 1 1 Common central domain of tyrosinase adh_short PF00106.20 EXF76189.1 - 2.1e-05 24.5 0.1 3.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.12 EXF76189.1 - 0.022 15.2 0.0 0.041 14.3 0.0 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EXF76189.1 - 0.11 12.3 0.1 0.2 11.4 0.1 1.5 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Abhydrolase_6 PF12697.2 EXF76190.1 - 1e-15 58.2 0.1 5.6e-08 32.9 0.0 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF76190.1 - 3.3e-08 33.4 0.0 1.4e-06 28.1 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF76190.1 - 0.0024 17.4 0.0 0.93 9.0 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EXF76190.1 - 0.014 15.1 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase Cellulase PF00150.13 EXF76191.1 - 1.7e-13 50.4 0.1 2.4e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) adh_short PF00106.20 EXF76192.1 - 2.6e-21 76.2 0.1 3.8e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF76192.1 - 3.8e-08 33.4 0.0 5.2e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF76192.1 - 1.4e-06 28.1 0.0 2.1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EXF76192.1 - 0.0099 15.5 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EXF76192.1 - 0.015 15.3 0.1 0.077 12.9 0.1 2.2 1 1 0 1 1 1 0 NADH(P)-binding MFS_1 PF07690.11 EXF76193.1 - 5.5e-37 127.2 19.0 5.5e-37 127.2 13.2 3.0 1 1 1 2 2 2 1 Major Facilitator Superfamily PGAP1 PF07819.8 EXF76193.1 - 1.5e-08 34.5 0.0 2.9e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Sugar_tr PF00083.19 EXF76193.1 - 4.4e-08 32.1 4.5 7.2e-08 31.4 3.1 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter NACHT PF05729.7 EXF76193.1 - 2.8e-07 30.3 0.0 8.6e-07 28.7 0.0 1.9 1 0 0 1 1 1 1 NACHT domain Abhydrolase_6 PF12697.2 EXF76193.1 - 2.9e-07 30.6 1.2 9.5e-07 28.9 0.1 2.4 3 0 0 3 3 3 1 Alpha/beta hydrolase family TRI12 PF06609.8 EXF76193.1 - 6.8e-05 21.2 4.7 0.00011 20.5 3.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF676 PF05057.9 EXF76193.1 - 0.00071 18.9 0.0 0.0017 17.6 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EXF76193.1 - 0.003 17.3 0.0 0.0086 15.8 0.0 1.8 1 0 0 1 1 1 1 Alpha/beta hydrolase family AAA_19 PF13245.1 EXF76193.1 - 0.0053 16.4 0.0 0.036 13.8 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain WD40 PF00400.27 EXF76193.1 - 0.0098 15.7 0.1 3.2 7.7 0.0 3.9 3 0 0 3 3 3 1 WD domain, G-beta repeat AAA_5 PF07728.9 EXF76193.1 - 0.016 14.9 0.0 0.053 13.2 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EXF76193.1 - 0.044 13.9 0.0 0.23 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EXF76193.1 - 0.078 13.1 0.1 0.46 10.6 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EXF76193.1 - 0.15 10.9 0.0 0.37 9.6 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain TMEM154 PF15102.1 EXF76194.1 - 0.00018 21.2 0.7 0.00031 20.4 0.4 1.4 1 1 0 1 1 1 1 TMEM154 protein family Herpes_gE PF02480.11 EXF76194.1 - 0.00034 19.0 0.9 0.00049 18.4 0.6 1.2 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E DUF1517 PF07466.6 EXF76194.1 - 0.001 18.0 1.1 0.001 18.0 0.8 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1517) EphA2_TM PF14575.1 EXF76194.1 - 0.007 16.7 0.0 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Rifin_STEVOR PF02009.11 EXF76194.1 - 0.041 13.5 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family DAP10 PF07213.6 EXF76194.1 - 0.064 13.0 0.3 0.28 10.9 0.0 2.2 2 0 0 2 2 2 0 DAP10 membrane protein SOG2 PF10428.4 EXF76194.1 - 3 6.3 14.3 4.6 5.7 9.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein EamA PF00892.15 EXF76195.1 - 1.6e-11 44.3 24.3 4.6e-07 29.9 0.3 3.0 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EXF76195.1 - 1.5e-05 25.1 0.3 1.5e-05 25.1 0.2 3.2 3 1 0 3 3 3 1 Multidrug resistance efflux transporter Nuc_sug_transp PF04142.10 EXF76195.1 - 0.0018 17.4 0.6 0.0054 15.8 0.4 1.8 1 1 0 1 1 1 1 Nucleotide-sugar transporter DUF914 PF06027.7 EXF76195.1 - 0.0023 16.8 0.9 0.0023 16.8 0.7 1.9 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 EXF76195.1 - 0.021 14.4 16.9 0.34 10.5 5.7 2.9 2 1 0 2 2 2 0 Triose-phosphate Transporter family Aldo_ket_red PF00248.16 EXF76196.1 - 1.7e-52 178.0 0.0 2e-52 177.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Ank PF00023.25 EXF76197.1 - 6.8e-10 38.2 0.2 1.8e-06 27.4 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EXF76197.1 - 2.4e-08 34.1 2.5 0.00023 21.4 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) KilA-N PF04383.8 EXF76197.1 - 3.7e-08 32.9 0.2 2.8e-07 30.1 0.1 2.3 1 1 0 1 1 1 1 KilA-N domain Ank_5 PF13857.1 EXF76197.1 - 8.9e-08 32.1 0.6 9.6e-07 28.8 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EXF76197.1 - 2.5e-06 27.8 0.8 0.00065 20.1 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF76197.1 - 0.0096 16.0 0.1 0.25 11.7 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat adh_short PF00106.20 EXF76200.1 - 1.4e-28 99.8 0.2 2.6e-28 99.0 0.0 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EXF76200.1 - 8.2e-12 45.1 0.2 4.9e-11 42.6 0.2 1.9 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF76200.1 - 6.3e-10 39.2 0.0 8.5e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EXF76200.1 - 1.8e-05 24.8 0.3 3e-05 24.1 0.2 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF76200.1 - 0.0008 18.9 0.1 0.0016 17.9 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EXF76200.1 - 0.0013 17.8 0.7 0.0018 17.4 0.5 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Saccharop_dh PF03435.13 EXF76200.1 - 0.057 12.3 0.1 0.082 11.8 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 EXF76200.1 - 0.06 13.1 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase F420_oxidored PF03807.12 EXF76200.1 - 0.097 13.1 0.1 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Uds1 PF15456.1 EXF76202.1 - 3.8e-05 23.6 0.9 3.8e-05 23.6 0.6 1.5 2 0 0 2 2 2 1 Up-regulated During Septation ALIX_LYPXL_bnd PF13949.1 EXF76202.1 - 0.0025 16.8 0.8 0.0036 16.3 0.5 1.3 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV GOLGA2L5 PF15070.1 EXF76202.1 - 0.0034 15.9 2.9 0.0039 15.7 2.0 1.1 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 DUF4164 PF13747.1 EXF76202.1 - 0.013 15.5 3.4 0.018 15.1 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Kinesin-relat_1 PF12711.2 EXF76202.1 - 0.019 15.3 3.1 0.031 14.6 2.1 1.4 1 0 0 1 1 1 0 Kinesin motor DUF515 PF04415.7 EXF76202.1 - 0.075 11.2 0.5 0.1 10.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Cep57_CLD_2 PF14197.1 EXF76202.1 - 0.075 12.9 2.8 0.91 9.5 0.5 2.2 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 DUF2361 PF10153.4 EXF76202.1 - 0.089 12.9 2.6 0.13 12.4 1.8 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) DUF972 PF06156.8 EXF76202.1 - 0.093 13.0 1.9 0.13 12.5 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) DUF2129 PF09902.4 EXF76202.1 - 0.12 12.2 0.3 0.25 11.1 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2129) DUF3251 PF11622.3 EXF76202.1 - 0.13 11.6 0.8 0.24 10.8 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3251) TMPIT PF07851.8 EXF76202.1 - 0.14 11.1 1.1 0.17 10.9 0.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein Mnd1 PF03962.10 EXF76202.1 - 0.16 11.6 4.8 0.41 10.2 3.3 1.6 1 1 0 1 1 1 0 Mnd1 family DUF1342 PF07072.6 EXF76202.1 - 0.33 10.5 2.8 0.27 10.8 0.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1342) Trypsin PF00089.21 EXF76204.1 - 3.3e-05 23.5 10.0 0.0001 21.9 7.0 1.7 1 1 0 1 1 1 1 Trypsin Pro_Al_protease PF02983.9 EXF76204.1 - 0.004 17.0 1.4 0.004 17.0 0.9 2.2 2 0 0 2 2 2 1 Alpha-lytic protease prodomain Cu-oxidase_3 PF07732.10 EXF76206.1 - 1.7e-41 140.6 3.4 3.8e-41 139.5 0.3 2.9 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EXF76206.1 - 4.3e-34 116.9 3.8 7.8e-28 96.7 0.3 4.1 4 0 0 4 4 4 3 Multicopper oxidase Cu-oxidase PF00394.17 EXF76206.1 - 2.5e-17 63.2 0.0 1.2e-15 57.7 0.0 2.9 2 1 0 2 2 2 1 Multicopper oxidase Cupredoxin_1 PF13473.1 EXF76206.1 - 0.035 13.9 0.0 0.12 12.3 0.0 1.9 1 1 0 1 1 1 0 Cupredoxin-like domain SGL PF08450.7 EXF76207.1 - 0.00059 19.2 0.0 0.00085 18.7 0.0 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region PQQ_2 PF13360.1 EXF76207.1 - 0.0052 16.2 3.4 0.038 13.4 2.2 2.2 1 1 0 1 1 1 1 PQQ-like domain DUF239 PF03080.10 EXF76207.1 - 0.026 13.6 0.0 0.047 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF239) Tachylectin PF14517.1 EXF76207.1 - 0.11 11.8 0.1 2.3 7.5 0.0 2.4 1 1 1 2 2 2 0 Tachylectin FMO-like PF00743.14 EXF76208.1 - 2.1e-89 300.1 0.0 2.5e-89 299.8 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EXF76208.1 - 4.3e-22 79.1 0.0 1.9e-20 73.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF76208.1 - 2e-11 43.4 0.1 1.3e-07 30.8 0.0 3.1 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EXF76208.1 - 1.2e-08 35.0 0.0 7.4e-07 29.2 0.0 2.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF76208.1 - 6.9e-08 32.4 0.1 0.018 14.8 0.0 3.4 3 0 0 3 3 3 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EXF76208.1 - 9.9e-07 28.6 0.0 2.5e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EXF76208.1 - 0.00027 21.2 0.2 1 9.8 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF76208.1 - 0.00055 19.0 0.4 0.0025 16.9 0.1 2.0 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EXF76208.1 - 0.00056 18.4 0.9 0.0011 17.5 0.2 1.7 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 EXF76208.1 - 0.0026 16.7 0.6 0.51 9.1 0.1 2.8 2 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF76208.1 - 0.011 14.5 0.0 0.016 14.0 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EXF76208.1 - 0.012 14.5 0.0 3.4 6.4 0.0 2.7 3 0 0 3 3 3 0 Glucose inhibited division protein A FAD_oxidored PF12831.2 EXF76208.1 - 0.034 13.2 0.2 0.052 12.6 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EXF76208.1 - 0.16 12.0 0.1 24 5.0 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EXF76208.1 - 0.19 10.7 0.1 0.36 9.8 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain adh_short PF00106.20 EXF76209.1 - 2.7e-08 33.9 0.0 4.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Zn_clus PF00172.13 EXF76210.1 - 1.5e-08 34.3 8.5 3.8e-08 33.1 5.9 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF76210.1 - 2.4e-05 23.1 0.4 4.3e-05 22.3 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Melibiase PF02065.13 EXF76211.1 - 1.3e-156 521.2 0.0 1.6e-156 520.9 0.0 1.1 1 0 0 1 1 1 1 Melibiase DUF187 PF02638.10 EXF76211.1 - 0.00067 18.6 0.0 0.001 17.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase like GH101 FAD_binding_3 PF01494.14 EXF76212.1 - 4e-24 85.3 0.0 9.7e-24 84.0 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain Amino_oxidase PF01593.19 EXF76212.1 - 5.6e-06 25.7 0.0 0.0027 16.8 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EXF76212.1 - 0.00067 18.6 0.1 0.25 10.2 0.0 2.4 3 0 0 3 3 3 2 Lycopene cyclase protein Pyr_redox PF00070.22 EXF76212.1 - 0.0056 17.0 0.9 0.01 16.2 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF76212.1 - 0.0086 15.0 0.1 2.8 6.7 0.0 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF76212.1 - 0.045 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EXF76212.1 - 0.07 11.7 0.0 6.9 5.1 0.0 2.8 3 0 0 3 3 3 0 Tryptophan halogenase Pyr_redox_2 PF07992.9 EXF76212.1 - 0.094 12.5 0.5 0.28 11.0 0.2 2.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Aminotran_1_2 PF00155.16 EXF76213.1 - 2.4e-37 128.7 0.0 3.2e-37 128.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EXF76213.1 - 0.0016 17.6 0.0 0.013 14.6 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase DinB PF05163.7 EXF76214.1 - 3.2e-19 69.2 0.3 3.6e-19 69.0 0.2 1.1 1 0 0 1 1 1 1 DinB family DinB_2 PF12867.2 EXF76214.1 - 4.1e-05 23.9 0.3 5e-05 23.6 0.2 1.1 1 0 0 1 1 1 1 DinB superfamily Aminotran_4 PF01063.14 EXF76216.1 - 7.2e-23 81.2 0.0 1.2e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV CTP_transf_2 PF01467.21 EXF76217.1 - 1.4e-11 44.6 0.0 4.9e-08 33.1 0.0 3.7 3 1 0 3 3 3 2 Cytidylyltransferase His_Phos_1 PF00300.17 EXF76218.1 - 6.7e-12 45.7 0.0 1e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) WD40 PF00400.27 EXF76220.1 - 6.9e-26 89.1 7.2 1.3e-05 24.8 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat FliO PF04347.8 EXF76220.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Flagellar biosynthesis protein, FliO Pyr_redox_3 PF13738.1 EXF76222.1 - 1.1e-22 81.0 0.0 1.7e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EXF76222.1 - 5.7e-14 51.2 0.1 2e-13 49.4 0.0 1.9 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EXF76222.1 - 7.8e-08 32.2 0.0 6.3e-07 29.3 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF76222.1 - 6.8e-05 22.8 0.0 0.24 11.2 0.0 2.8 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF76222.1 - 0.00011 21.4 0.0 0.0045 16.1 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.7 EXF76222.1 - 0.001 18.0 0.0 0.034 13.0 0.0 2.7 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 EXF76222.1 - 0.0013 17.7 2.9 0.029 13.2 0.1 3.0 3 1 1 4 4 4 1 FAD dependent oxidoreductase GIDA PF01134.17 EXF76222.1 - 0.052 12.4 0.9 2.2 7.0 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Mqo PF06039.10 EXF76222.1 - 0.091 10.9 0.0 1.2 7.2 0.0 2.1 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) RDM PF11002.3 EXF76223.1 - 0.00022 20.8 4.2 24 4.6 0.0 5.2 5 0 0 5 5 5 0 RFPL defining motif (RDM) TORC_C PF12886.2 EXF76223.1 - 0.0025 17.9 1.7 20 5.4 0.0 4.1 2 1 0 3 3 3 0 Transducer of regulated CREB activity, C terminus TipAS PF07739.8 EXF76223.1 - 0.035 14.4 3.4 0.79 10.0 0.3 2.5 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain DUF2088 PF09861.4 EXF76223.1 - 0.063 12.3 0.0 7 5.6 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2088) Erythro-docking PF09277.6 EXF76223.1 - 0.15 11.7 6.0 2.2 8.0 0.7 2.3 2 0 0 2 2 2 0 Erythronolide synthase, docking Sigma54_AID PF00309.15 EXF76223.1 - 0.19 11.2 1.9 3.9 7.0 0.1 2.4 2 0 0 2 2 2 0 Sigma-54 factor, Activator interacting domain (AID) DUF2984 PF11203.3 EXF76223.1 - 0.37 10.9 2.9 2.1 8.5 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2984) DUF2547 PF10818.3 EXF76223.1 - 0.45 11.1 3.6 7.5 7.2 0.7 2.8 1 1 0 2 2 2 0 Protein of unknown function (DUF2547) DUF3349 PF11829.3 EXF76223.1 - 2.2 8.7 6.8 7.4 7.0 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3349) Gallidermin PF02052.10 EXF76223.1 - 2.7 8.1 10.9 2.6 8.2 0.3 3.4 2 1 2 4 4 4 0 Gallidermin DWNN PF08783.6 EXF76223.1 - 5.6 6.9 11.2 23 5.0 0.1 4.1 2 1 3 5 5 5 0 DWNN domain TPR_14 PF13428.1 EXF76223.1 - 9.6 7.1 10.8 14 6.6 0.3 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 EXF76224.1 - 6.3e-23 81.8 0.0 8e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF76224.1 - 9.6e-18 64.5 0.0 2.8e-17 63.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF76224.1 - 6.3e-11 42.2 0.1 7.5e-10 38.7 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EXF76224.1 - 1.4e-05 24.4 0.2 0.0019 17.4 0.0 2.1 2 0 0 2 2 2 2 Dienelactone hydrolase family FSH1 PF03959.8 EXF76224.1 - 0.001 18.5 0.0 0.0096 15.3 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.5 EXF76224.1 - 0.0027 17.5 0.0 0.0049 16.7 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein BAAT_C PF08840.6 EXF76224.1 - 0.044 13.4 0.1 0.35 10.5 0.0 2.0 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 EXF76224.1 - 0.1 11.8 0.0 0.21 10.8 0.0 1.6 1 1 0 1 1 1 0 Prolyl oligopeptidase family Esterase PF00756.15 EXF76224.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Hydrolase_4 PF12146.3 EXF76224.1 - 0.12 12.1 0.0 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 Putative lysophospholipase ADH_N PF08240.7 EXF76225.1 - 5.5e-18 64.7 2.6 2.2e-17 62.7 0.1 2.9 2 2 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF76225.1 - 6.9e-16 57.9 3.1 3.5e-15 55.7 2.2 2.2 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF76225.1 - 1.6e-05 25.8 0.4 0.00012 23.0 0.1 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.10 EXF76225.1 - 0.0017 18.2 1.7 0.017 15.0 0.2 2.3 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EXF76225.1 - 0.0017 17.5 0.5 0.0033 16.6 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EXF76225.1 - 0.0045 16.5 1.1 0.0053 16.3 0.1 1.5 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain UDPG_MGDP_dh_N PF03721.9 EXF76225.1 - 0.027 13.8 0.1 0.053 12.9 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Gp_dh_N PF00044.19 EXF76225.1 - 0.057 13.3 0.6 0.58 10.1 0.1 2.2 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Methyltransf_2 PF00891.13 EXF76227.1 - 2.9e-29 101.9 0.0 3.9e-29 101.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_31 PF13847.1 EXF76227.1 - 0.013 15.0 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EXF76227.1 - 0.044 14.3 0.0 0.22 12.1 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain HTH_Tnp_ISL3 PF13542.1 EXF76227.1 - 0.14 11.3 0.1 0.46 9.7 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 p450 PF00067.17 EXF76228.1 - 4.6e-44 150.7 0.0 7.2e-44 150.0 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 Gly_transf_sug PF04488.10 EXF76229.1 - 7.1e-09 35.9 0.2 1.2e-08 35.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.2 EXF76229.1 - 0.0048 15.4 1.2 0.0092 14.5 0.0 2.0 2 0 0 2 2 2 1 TcdA/TcdB catalytic glycosyltransferase domain Caps_synth PF05704.7 EXF76229.1 - 0.052 12.7 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein Sial-lect-inser PF09264.5 EXF76229.1 - 0.09 12.0 0.1 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Vibrio cholerae sialidase, lectin insertion PS_Dcarbxylase PF02666.10 EXF76230.1 - 2.1e-48 164.3 0.0 2.6e-48 164.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase MFS_1 PF07690.11 EXF76231.1 - 6.5e-29 100.7 37.2 2e-28 99.1 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF76231.1 - 2.1e-14 52.9 6.7 4.2e-14 51.9 4.7 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter AAA PF00004.24 EXF76232.1 - 1.9e-15 57.2 0.0 3.8e-15 56.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EXF76232.1 - 4.1e-05 23.7 0.3 0.0028 17.7 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EXF76232.1 - 0.0017 18.4 0.2 0.0065 16.4 0.1 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EXF76232.1 - 0.0082 15.8 0.1 0.021 14.5 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EXF76232.1 - 0.02 14.5 0.0 0.066 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) HMG-CoA_red PF00368.13 EXF76233.1 - 2.6e-156 519.9 4.2 3.4e-156 519.5 2.9 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase HPIH PF13323.1 EXF76233.1 - 6.6e-49 165.5 3.0 1.4e-48 164.4 2.1 1.6 1 0 0 1 1 1 1 N-terminal domain with HPIH motif Sterol-sensing PF12349.3 EXF76233.1 - 3.7e-13 49.2 4.7 1.8e-11 43.7 3.3 2.5 1 1 0 1 1 1 1 Sterol-sensing domain of SREBP cleavage-activation Patched PF02460.13 EXF76233.1 - 1e-05 23.7 0.7 1.7e-05 22.9 0.5 1.3 1 0 0 1 1 1 1 Patched family Lig_chan PF00060.21 EXF76233.1 - 0.0033 17.1 2.0 1.3 8.7 0.0 2.5 2 0 0 2 2 2 2 Ligand-gated ion channel Isochorismatase PF00857.15 EXF76234.1 - 5e-24 85.1 0.0 8.4e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 Isochorismatase family S1-P1_nuclease PF02265.11 EXF76235.1 - 9e-62 208.9 0.0 1e-61 208.7 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease ECH PF00378.15 EXF76236.1 - 2.3e-38 131.7 0.0 2.9e-38 131.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family NAD_binding_8 PF13450.1 EXF76237.1 - 6.2e-12 45.3 0.2 1.5e-11 44.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF76237.1 - 1.6e-09 37.1 0.0 3.2e-08 32.8 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EXF76237.1 - 5e-06 26.7 0.3 2.2e-05 24.6 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF76237.1 - 5.4e-05 23.5 0.0 0.43 11.0 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF76237.1 - 0.00015 21.7 0.0 0.018 14.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF76237.1 - 0.00033 19.6 0.0 0.00057 18.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EXF76237.1 - 0.00043 18.8 0.1 0.022 13.2 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_9 PF13454.1 EXF76237.1 - 0.0014 18.4 0.0 0.01 15.6 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EXF76237.1 - 0.0095 14.8 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EXF76237.1 - 0.0098 15.0 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Shikimate_DH PF01488.15 EXF76237.1 - 0.027 14.5 0.0 0.052 13.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EXF76237.1 - 0.14 11.2 0.0 0.45 9.5 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain zf-C2H2_2 PF12756.2 EXF76238.1 - 4.2e-23 81.3 0.3 8.6e-23 80.3 0.2 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EXF76238.1 - 0.019 15.0 0.2 0.05 13.7 0.1 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding adh_short PF00106.20 EXF76241.1 - 2e-09 37.6 0.2 5.7e-06 26.3 0.1 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EXF76241.1 - 0.016 14.9 0.0 2.9 7.5 0.0 2.2 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase OmdA PF13376.1 EXF76242.1 - 4.9e-09 35.7 1.0 1.1e-08 34.5 0.4 1.8 2 0 0 2 2 2 1 Bacteriocin-protection, YdeI or OmpD-Associated DUF2199 PF09965.4 EXF76242.1 - 0.088 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2199) Lipase_GDSL_2 PF13472.1 EXF76244.1 - 3.8e-15 56.4 0.8 7.3e-15 55.5 0.5 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EXF76244.1 - 1.1e-09 38.4 2.1 1.6e-08 34.6 1.4 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DUF4190 PF13828.1 EXF76245.1 - 2.3 7.8 10.3 6.7 6.3 1.3 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4190) WD40 PF00400.27 EXF76246.1 - 1.1e-16 60.0 10.6 7e-08 32.0 0.8 6.0 5 0 0 5 5 5 4 WD domain, G-beta repeat Zn_Tnp_IS1595 PF12760.2 EXF76246.1 - 0.0064 16.2 1.5 0.0064 16.2 1.0 2.8 4 0 0 4 4 4 1 Transposase zinc-ribbon domain zinc_ribbon_5 PF13719.1 EXF76246.1 - 0.38 10.3 4.8 0.055 13.0 0.2 2.0 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EXF76246.1 - 1.2 8.9 5.0 0.16 11.6 0.3 2.0 2 0 0 2 2 2 0 zinc-ribbon domain Atg14 PF10186.4 EXF76247.1 - 1.5e-20 73.3 0.0 2.6e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EXF76247.1 - 0.00044 19.4 8.2 0.0032 16.5 5.0 2.3 2 1 0 2 2 2 1 Autophagy protein Apg6 Snapin_Pallidin PF14712.1 EXF76247.1 - 2.6 8.4 7.2 17 5.8 2.8 2.7 1 1 1 2 2 2 0 Snapin/Pallidin DUF1205 PF06722.7 EXF76248.1 - 0.074 13.2 0.1 5.8 7.2 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1205) adh_short PF00106.20 EXF76251.1 - 5.8e-18 65.3 0.1 1.3e-17 64.1 0.1 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EXF76251.1 - 2.4e-08 33.8 0.2 4.5e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF76251.1 - 1e-05 25.4 0.0 1.6e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EXF76251.1 - 6.6e-05 22.9 0.2 0.00019 21.5 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding ADH_zinc_N PF00107.21 EXF76251.1 - 0.0017 17.9 0.0 0.0077 15.7 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Epimerase PF01370.16 EXF76251.1 - 0.0031 17.0 0.0 0.0056 16.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Fungal_trans_2 PF11951.3 EXF76252.1 - 0.0077 14.8 0.2 0.0098 14.5 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.18 EXF76253.1 - 2.8e-27 94.8 6.5 8.4e-27 93.3 4.5 1.9 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF76253.1 - 1.9e-13 50.1 0.4 3.6e-13 49.1 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cupin_1 PF00190.17 EXF76254.1 - 2.5e-11 43.1 0.1 3.2e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EXF76254.1 - 2e-08 33.6 0.0 3.9e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 EXF76254.1 - 0.026 14.1 0.0 0.034 13.7 0.0 1.2 1 0 0 1 1 1 0 Cupin Tyrosinase PF00264.15 EXF76255.1 - 6.5e-38 131.1 1.3 1e-37 130.4 0.9 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase AHSA1 PF08327.6 EXF76255.1 - 0.053 13.6 0.0 0.46 10.5 0.0 2.1 2 0 0 2 2 2 0 Activator of Hsp90 ATPase homolog 1-like protein Transferase PF02458.10 EXF76256.1 - 3.8e-27 94.8 0.0 2.8e-26 91.9 0.0 1.8 2 0 0 2 2 2 1 Transferase family CheR_N PF03705.10 EXF76257.1 - 0.01 15.1 0.2 0.074 12.4 0.0 2.3 2 0 0 2 2 2 0 CheR methyltransferase, all-alpha domain Mu-like_Pro PF10123.4 EXF76257.1 - 0.14 11.6 3.1 0.18 11.2 2.1 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein IncA PF04156.9 EXF76257.1 - 0.49 9.9 9.1 1.1 8.8 6.3 1.4 1 1 0 1 1 1 0 IncA protein UVR PF02151.14 EXF76257.1 - 2 8.0 0.0 2 8.0 0.0 3.6 4 0 0 4 4 4 0 UvrB/uvrC motif TPR_MLP1_2 PF07926.7 EXF76257.1 - 7.6 6.2 8.7 1.6 8.4 0.3 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein MFS_1 PF07690.11 EXF76258.1 - 1.3e-22 79.9 22.1 1.3e-22 79.9 15.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1479 PF07350.7 EXF76259.1 - 0.0024 16.4 0.0 0.0037 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) MFS_1 PF07690.11 EXF76260.1 - 1.5e-31 109.4 35.6 1.5e-31 109.4 24.7 1.5 1 1 1 2 2 2 2 Major Facilitator Superfamily NmrA PF05368.8 EXF76261.1 - 8.7e-10 38.2 0.0 5.3e-09 35.6 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF76261.1 - 1.1e-08 35.3 0.0 2e-08 34.4 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding MFS_1 PF07690.11 EXF76262.1 - 3e-21 75.5 50.8 3e-21 75.5 35.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily EthD PF07110.6 EXF76263.1 - 0.056 14.3 0.0 0.063 14.2 0.0 1.1 1 0 0 1 1 1 0 EthD domain DJ-1_PfpI PF01965.19 EXF76264.1 - 5.3e-15 55.1 0.0 1.3e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 DJ-1/PfpI family DJ-1_PfpI_N PF13587.1 EXF76264.1 - 4.6e-08 32.4 0.0 9.4e-08 31.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family Fungal_trans_2 PF11951.3 EXF76264.1 - 0.00042 19.0 1.2 0.00097 17.8 0.4 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Epimerase PF01370.16 EXF76265.1 - 2.2e-16 60.0 0.0 2.9e-16 59.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EXF76265.1 - 8.9e-13 47.5 0.0 1.5e-12 46.8 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EXF76265.1 - 2e-11 43.2 0.0 2.3e-10 39.8 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EXF76265.1 - 4e-09 36.7 0.1 9.8e-09 35.4 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EXF76265.1 - 3.3e-07 29.5 0.0 4.2e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EXF76265.1 - 2.8e-05 24.0 0.8 2.8e-05 24.0 0.6 2.2 2 1 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 EXF76265.1 - 9.4e-05 21.7 0.0 0.00018 20.8 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 EXF76265.1 - 0.00024 20.8 0.1 0.00045 19.9 0.1 1.5 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EXF76266.1 - 2.5e-05 23.4 0.0 3.6e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 EXF76266.1 - 4.7e-05 22.7 0.0 6.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF76266.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Glyco_hydro_20 PF00728.17 EXF76267.1 - 0.099 11.7 0.1 0.17 11.0 0.0 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 20, catalytic domain OpuAC PF04069.7 EXF76268.1 - 0.014 14.7 0.0 0.023 14.0 0.0 1.3 1 0 0 1 1 1 0 Substrate binding domain of ABC-type glycine betaine transport system SnoaL_2 PF12680.2 EXF76269.1 - 0.0021 18.4 0.0 0.0035 17.7 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF2358 PF10184.4 EXF76269.1 - 0.055 13.3 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) zf-RING_2 PF13639.1 EXF76270.1 - 2.8e-08 33.4 7.1 2.8e-08 33.4 4.9 1.9 2 0 0 2 2 2 1 Ring finger domain FANCL_C PF11793.3 EXF76270.1 - 9.7e-07 28.6 10.8 2.4e-06 27.4 4.9 2.3 2 0 0 2 2 2 1 FANCL C-terminal domain zf-rbx1 PF12678.2 EXF76270.1 - 0.0012 18.8 3.5 0.0012 18.8 2.4 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EXF76270.1 - 0.01 15.5 7.5 0.01 15.5 5.2 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-Apc11 PF12861.2 EXF76270.1 - 0.011 15.5 6.1 0.011 15.5 4.2 2.0 1 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.1 EXF76270.1 - 0.028 14.4 7.9 0.028 14.4 5.5 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) SWIM PF04434.12 EXF76270.1 - 0.072 12.5 0.3 0.15 11.5 0.2 1.6 1 0 0 1 1 1 0 SWIM zinc finger Pol_alpha_B_N PF08418.5 EXF76270.1 - 0.082 12.4 6.4 0.12 11.8 4.4 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal SoxE PF06525.6 EXF76270.1 - 1.1 8.5 3.1 1.8 7.8 2.1 1.3 1 0 0 1 1 1 0 Sulfocyanin (SoxE) ORC6 PF05460.8 EXF76270.1 - 1.9 7.4 7.9 2.8 6.9 5.5 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) zf-C3HC4_3 PF13920.1 EXF76270.1 - 5.5 6.7 13.1 0.049 13.3 3.4 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rad4 PF03835.10 EXF76270.1 - 8 5.8 7.5 4.7 6.6 0.2 3.2 2 2 0 2 2 2 0 Rad4 transglutaminase-like domain RINGv PF12906.2 EXF76270.1 - 9 6.4 17.1 0.11 12.5 6.4 1.9 2 0 0 2 2 2 0 RING-variant domain DUF1751 PF08551.5 EXF76271.1 - 1.9e-26 92.3 4.3 4.2e-26 91.1 3.0 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EXF76271.1 - 0.57 10.1 9.7 1.5 8.8 6.8 1.7 1 1 0 1 1 1 0 Rhomboid family WD40 PF00400.27 EXF76272.1 - 5.5e-11 41.9 6.9 0.0014 18.4 0.0 6.6 8 0 0 8 8 8 3 WD domain, G-beta repeat LisH PF08513.6 EXF76272.1 - 1.1e-06 28.1 0.1 2.5e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 LisH IKI3 PF04762.7 EXF76272.1 - 0.048 11.4 0.0 0.13 10.0 0.0 1.6 2 0 0 2 2 2 0 IKI3 family RRM_1 PF00076.17 EXF76273.1 - 2.1e-31 107.3 0.0 6e-15 54.6 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF76273.1 - 1e-23 83.0 0.0 4.3e-12 45.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF76273.1 - 6.8e-09 35.4 0.0 0.0013 18.5 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 EXF76273.1 - 0.032 13.8 0.2 6.4 6.5 0.0 2.8 3 0 0 3 3 3 0 DbpA RNA binding domain Limkain-b1 PF11608.3 EXF76273.1 - 0.13 12.0 0.4 23 4.8 0.1 2.7 3 0 0 3 3 3 0 Limkain b1 API5 PF05918.6 EXF76273.1 - 0.22 9.9 3.6 0.33 9.3 2.5 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Gly-rich_Ago1 PF12764.2 EXF76273.1 - 2.8 8.6 10.9 0.56 10.8 4.3 2.4 2 0 0 2 2 2 0 Glycine-rich region of argonaut ETF PF01012.16 EXF76274.1 - 6.4e-37 126.7 0.4 1.2e-36 125.9 0.3 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ArfGap PF01412.13 EXF76274.1 - 2e-32 111.4 0.2 3.7e-32 110.5 0.2 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PEP_mutase PF13714.1 EXF76275.1 - 2.8e-53 180.5 1.3 3.2e-53 180.3 0.9 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EXF76275.1 - 9.9e-21 73.5 1.1 1.3e-20 73.0 0.8 1.1 1 0 0 1 1 1 1 Isocitrate lyase family DUF575 PF04746.7 EXF76275.1 - 0.11 12.4 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF575) MFS_1 PF07690.11 EXF76276.1 - 6.3e-24 84.3 23.8 3e-23 82.1 16.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily FA_desaturase PF00487.19 EXF76276.1 - 0.12 11.7 0.1 0.12 11.7 0.1 3.1 2 2 0 3 3 3 0 Fatty acid desaturase GATase PF00117.23 EXF76277.1 - 3.4e-47 160.3 0.0 4.6e-47 159.9 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EXF76277.1 - 2.2e-46 156.5 0.0 3.3e-46 156.0 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain Peptidase_C26 PF07722.8 EXF76277.1 - 3.3e-06 26.7 0.2 0.00043 19.8 0.1 2.6 1 1 0 1 1 1 1 Peptidase C26 KTI12 PF08433.5 EXF76278.1 - 0.034 13.3 0.0 0.051 12.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 PRK PF00485.13 EXF76278.1 - 0.037 13.5 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ArgK PF03308.11 EXF76278.1 - 0.065 12.0 0.0 0.096 11.4 0.0 1.1 1 0 0 1 1 1 0 ArgK protein AAA_17 PF13207.1 EXF76278.1 - 0.15 12.9 0.2 0.52 11.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain SAP PF02037.22 EXF76279.1 - 3.1e-12 45.6 0.5 5.5e-12 44.8 0.4 1.4 1 0 0 1 1 1 1 SAP domain GATA PF00320.22 EXF76281.1 - 1.6e-31 107.3 18.5 3.7e-17 61.3 2.3 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.7 EXF76281.1 - 9.4e-06 24.8 5.2 0.0075 15.5 0.3 2.5 2 0 0 2 2 2 2 TFIIB zinc-binding ArfGap PF01412.13 EXF76281.1 - 0.0015 18.3 1.7 0.51 10.1 0.2 2.4 2 0 0 2 2 2 2 Putative GTPase activating protein for Arf RRN7 PF11781.3 EXF76281.1 - 0.0019 17.6 8.2 0.22 11.0 0.4 2.6 2 0 0 2 2 2 2 RNA polymerase I-specific transcription initiation factor Rrn7 Zn-ribbon_8 PF09723.5 EXF76281.1 - 0.04 13.8 6.4 1.2 9.1 0.1 2.8 3 0 0 3 3 2 0 Zinc ribbon domain Auto_anti-p27 PF06677.7 EXF76281.1 - 0.047 13.4 4.0 1.2 8.9 0.2 2.6 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-Sec23_Sec24 PF04810.10 EXF76281.1 - 0.048 13.2 0.5 0.048 13.2 0.3 3.2 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger NMD3 PF04981.8 EXF76281.1 - 0.064 12.3 2.1 1.7 7.7 0.1 2.3 2 0 0 2 2 2 0 NMD3 family zf-ribbon_3 PF13248.1 EXF76281.1 - 0.21 10.8 10.7 0.38 10.0 0.2 3.2 2 1 0 2 2 2 0 zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EXF76281.1 - 0.42 10.3 15.5 0.044 13.4 1.3 2.9 3 0 0 3 3 3 0 Putative transposase DNA-binding domain DZR PF12773.2 EXF76281.1 - 0.52 10.1 15.7 0.38 10.6 0.4 3.1 2 1 0 2 2 2 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.2 EXF76281.1 - 0.9 9.3 7.4 2 8.3 0.8 2.7 2 0 0 2 2 2 0 Transposase zinc-ribbon domain eIF-5_eIF-2B PF01873.12 EXF76281.1 - 2.2 7.9 6.4 6.1 6.5 0.3 2.2 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Ribosomal_L32p PF01783.18 EXF76281.1 - 2.5 8.3 12.3 6.8 6.9 1.7 4.5 3 2 0 3 3 3 0 Ribosomal L32p protein family COPI_assoc PF08507.5 EXF76282.1 - 1.9e-44 150.6 6.9 2.1e-44 150.5 4.8 1.0 1 0 0 1 1 1 1 COPI associated protein DUF1113 PF06541.6 EXF76282.1 - 0.0079 15.9 1.0 0.011 15.4 0.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1113) UCR_Fe-S_N PF10399.4 EXF76282.1 - 0.083 12.0 1.3 0.09 11.9 0.0 1.7 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Oxidored_q3 PF00499.15 EXF76282.1 - 0.2 11.4 11.5 0.27 11.0 8.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF3784 PF12650.2 EXF76282.1 - 0.47 10.4 10.8 0.24 11.3 1.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) Neurensin PF14927.1 EXF76282.1 - 2 7.7 5.5 0.38 10.1 0.4 2.2 1 1 2 3 3 3 0 Neurensin Cg6151-P PF10233.4 EXF76282.1 - 2.8 7.9 11.1 15 5.5 7.5 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein CG6151-P GTP_EFTU PF00009.22 EXF76283.1 - 1.4e-50 171.3 0.0 2.5e-50 170.5 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EXF76283.1 - 4.4e-22 77.7 0.0 9.1e-22 76.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EXF76283.1 - 1e-11 44.5 0.0 8.2e-11 41.6 0.0 2.4 1 1 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EXF76283.1 - 0.00012 22.0 0.0 0.00036 20.5 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EXF76283.1 - 0.00013 21.4 0.1 0.0003 20.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV Miro PF08477.8 EXF76283.1 - 0.03 14.8 0.0 0.067 13.6 0.0 1.7 1 0 0 1 1 1 0 Miro-like protein MmgE_PrpD PF03972.9 EXF76284.1 - 2.1e-23 82.2 4.9 1.6e-12 46.3 2.4 2.1 1 1 1 2 2 2 2 MmgE/PrpD family Cupin_1 PF00190.17 EXF76285.1 - 3.6e-09 36.1 0.1 5.3e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EXF76285.1 - 0.036 13.5 0.0 0.083 12.4 0.0 1.7 1 1 0 1 1 1 0 Cupin domain SUN PF03856.8 EXF76286.1 - 2.7e-69 233.2 15.9 4.4e-69 232.5 11.0 1.3 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) IER PF05760.7 EXF76286.1 - 0.28 11.0 11.2 0.5 10.2 7.8 1.3 1 0 0 1 1 1 0 Immediate early response protein (IER) BAT2_N PF07001.6 EXF76286.1 - 5 7.4 19.2 0.63 10.3 8.6 2.1 1 1 1 2 2 2 0 BAT2 N-terminus DUF2486 PF10667.4 EXF76286.1 - 5.4 7.4 10.4 8.2 6.8 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) MFS_1 PF07690.11 EXF76287.1 - 1e-36 126.4 29.0 1.4e-36 125.9 18.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily V_ATPase_I PF01496.14 EXF76287.1 - 0.095 10.5 0.1 0.31 8.8 0.0 1.7 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family LCM PF04072.9 EXF76289.1 - 3.3e-21 75.6 0.0 7.4e-21 74.5 0.0 1.5 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase Mito_carr PF00153.22 EXF76290.1 - 0.01 15.4 0.2 2.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial carrier protein Kinesin PF00225.18 EXF76291.1 - 4.8e-113 377.2 0.4 1.3e-112 375.8 0.3 1.8 1 0 0 1 1 1 1 Kinesin motor domain Filament PF00038.16 EXF76291.1 - 8.9 5.6 64.6 2.8 7.3 18.3 3.7 1 1 2 3 3 3 0 Intermediate filament protein UQ_con PF00179.21 EXF76292.1 - 1.1e-51 173.8 0.0 1.3e-51 173.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EXF76292.1 - 1e-06 28.5 0.0 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EXF76292.1 - 0.021 14.6 0.1 0.035 14.0 0.1 1.6 1 1 0 1 1 1 0 RWD domain Thiolase_N PF00108.18 EXF76293.1 - 7.6e-93 310.2 0.2 1.2e-92 309.6 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EXF76293.1 - 1.7e-37 127.5 1.0 3.9e-37 126.3 0.7 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EXF76293.1 - 0.0053 16.2 0.6 0.021 14.3 0.2 1.8 1 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PCI PF01399.22 EXF76294.1 - 0.00033 20.9 0.1 0.019 15.2 0.0 2.5 2 0 0 2 2 2 2 PCI domain Clat_adaptor_s PF01217.15 EXF76295.1 - 3.1e-56 189.0 1.7 3.4e-56 188.8 1.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-CCHC_2 PF13696.1 EXF76296.1 - 2.5e-05 23.6 17.1 0.00062 19.1 2.9 2.6 1 1 1 2 2 2 2 Zinc knuckle zf-Mss51 PF13824.1 EXF76296.1 - 1.1 9.1 6.5 2.1 8.2 0.3 2.7 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-CCHC PF00098.18 EXF76296.1 - 3.2 7.8 9.9 0.54 10.2 1.3 2.7 2 1 0 2 2 2 0 Zinc knuckle Ist1 PF03398.9 EXF76297.1 - 1.7e-64 216.2 1.2 1.7e-64 216.2 0.8 1.6 2 0 0 2 2 2 1 Regulator of Vps4 activity in the MVB pathway TFIID-18kDa PF02269.11 EXF76297.1 - 3.6e-27 94.0 2.0 2.4e-26 91.3 0.1 3.0 4 0 0 4 4 4 1 Transcription initiation factor IID, 18kD subunit Myc_N PF01056.13 EXF76297.1 - 0.031 13.4 0.6 0.058 12.5 0.4 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Citrate_synt PF00285.16 EXF76298.1 - 9e-70 235.1 0.0 1.3e-69 234.5 0.0 1.2 1 0 0 1 1 1 1 Citrate synthase Fungal_trans_2 PF11951.3 EXF76298.1 - 4.5e-06 25.5 0.7 5.2e-05 22.0 0.1 2.2 2 0 0 2 2 2 1 Fungal specific transcription factor domain G-patch_2 PF12656.2 EXF76298.1 - 0.0067 16.2 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 DExH-box splicing factor binding site DUF3500 PF12006.3 EXF76299.1 - 6.4e-63 212.5 0.0 7.4e-63 212.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3500) p450 PF00067.17 EXF76300.1 - 2.5e-42 144.9 0.0 9.9e-28 96.8 0.0 2.5 2 1 0 2 2 2 2 Cytochrome P450 Dockerin_1 PF00404.13 EXF76301.1 - 3.3 7.5 4.9 0.58 9.9 0.7 1.9 2 0 0 2 2 2 0 Dockerin type I repeat DAO PF01266.19 EXF76302.1 - 3e-42 144.8 0.0 3.9e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EXF76302.1 - 8.1e-05 22.7 0.0 0.0036 17.3 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF76302.1 - 9.2e-05 22.3 0.1 0.00027 20.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EXF76302.1 - 0.00049 19.9 0.3 0.0053 16.5 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EXF76302.1 - 0.0066 15.3 1.3 0.093 11.5 0.9 2.1 1 1 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EXF76302.1 - 0.012 14.0 0.1 3.3 6.0 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.7 EXF76302.1 - 0.014 14.3 0.1 0.033 13.1 0.1 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein K_oxygenase PF13434.1 EXF76302.1 - 0.04 12.8 0.0 0.074 11.9 0.0 1.4 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EXF76302.1 - 0.059 13.2 0.2 1.2 8.9 0.1 2.1 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PDZ_1 PF12812.2 EXF76304.1 - 2.9e-55 184.0 0.1 1.3e-34 117.9 0.0 2.7 2 0 0 2 2 2 2 PDZ-like domain PDZ_2 PF13180.1 EXF76304.1 - 7.9e-15 54.5 3.2 4.4e-07 29.6 0.2 4.4 4 0 0 4 4 4 3 PDZ domain Trypsin_2 PF13365.1 EXF76304.1 - 1.4e-14 54.1 0.7 1.8e-12 47.2 0.0 3.1 2 1 0 2 2 2 1 Trypsin-like peptidase domain PDZ PF00595.19 EXF76304.1 - 7.2e-08 32.5 0.0 0.001 19.2 0.0 3.8 4 0 0 4 4 4 2 PDZ domain (Also known as DHR or GLGF) Tricorn_PDZ PF14685.1 EXF76304.1 - 0.0003 20.5 0.4 0.0045 16.7 0.2 2.8 3 0 0 3 3 3 1 Tricorn protease PDZ domain Trypsin PF00089.21 EXF76304.1 - 0.00055 19.5 0.0 0.004 16.7 0.0 2.4 3 0 0 3 3 3 1 Trypsin DnaJ PF00226.26 EXF76305.1 - 1.6e-22 79.0 1.6 3.2e-22 78.0 1.1 1.5 1 0 0 1 1 1 1 DnaJ domain CDC73 PF05179.9 EXF76306.1 - 6.3e-44 150.3 0.0 1.2e-43 149.5 0.0 1.4 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Bystin PF05291.6 EXF76307.1 - 1e-119 398.9 0.0 1.4e-119 398.5 0.0 1.1 1 0 0 1 1 1 1 Bystin DUF383 PF04063.9 EXF76308.1 - 2e-67 226.4 1.0 1.3e-66 223.7 0.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EXF76308.1 - 3.9e-22 77.5 0.1 1.1e-21 76.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF384) Proteasom_PSMB PF10508.4 EXF76308.1 - 0.00063 18.1 0.3 0.0018 16.6 0.2 1.6 1 1 1 2 2 2 1 Proteasome non-ATPase 26S subunit V-ATPase_H_N PF03224.9 EXF76308.1 - 0.0027 16.8 0.4 0.0048 16.0 0.2 1.5 1 1 0 1 1 1 1 V-ATPase subunit H Adaptin_N PF01602.15 EXF76308.1 - 0.0071 14.7 0.3 0.013 13.8 0.2 1.4 1 0 0 1 1 1 1 Adaptin N terminal region DUF427 PF04248.7 EXF76309.1 - 8.8e-32 108.6 1.2 1e-31 108.4 0.8 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF427) DUF221 PF02714.10 EXF76310.1 - 1.7e-99 332.7 19.3 1.7e-99 332.7 13.4 2.3 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EXF76310.1 - 7.1e-39 132.8 0.3 7.1e-39 132.8 0.2 3.2 2 1 1 3 3 3 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EXF76310.1 - 1.8e-17 63.0 0.0 4.9e-17 61.5 0.0 1.8 1 0 0 1 1 1 1 Phosphate metabolism protein DUF4463 PF14703.1 EXF76310.1 - 6.8e-08 32.9 12.0 0.0011 19.3 4.9 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4463) FAD_binding_3 PF01494.14 EXF76311.1 - 3.6e-18 65.7 0.0 1.6e-11 43.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EXF76311.1 - 1.5e-07 31.2 0.3 3.6e-07 30.1 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF76311.1 - 0.0018 17.2 0.9 0.0035 16.2 0.6 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF76311.1 - 0.0022 17.9 0.7 0.0039 17.0 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF76311.1 - 0.0025 16.7 0.8 0.0045 15.9 0.6 1.4 1 0 0 1 1 1 1 FAD binding domain ThiF PF00899.16 EXF76311.1 - 0.016 15.0 0.7 0.038 13.8 0.2 1.9 2 0 0 2 2 2 0 ThiF family Pyr_redox_3 PF13738.1 EXF76311.1 - 0.026 14.6 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF76311.1 - 0.029 13.4 0.1 0.046 12.7 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 EXF76311.1 - 0.047 14.1 0.1 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF76311.1 - 0.12 12.0 0.4 0.27 10.9 0.2 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 EXF76311.1 - 0.15 10.9 1.1 0.22 10.3 0.7 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 EXF76311.1 - 0.18 10.2 0.6 0.31 9.4 0.4 1.3 1 0 0 1 1 1 0 HI0933-like protein F420_oxidored PF03807.12 EXF76311.1 - 0.24 11.8 1.0 0.57 10.6 0.7 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 EXF76311.1 - 0.42 9.9 2.0 0.39 10.0 0.4 1.6 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain SOG2 PF10428.4 EXF76313.1 - 1.2 7.7 5.6 1.4 7.4 3.9 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein DUF566 PF04484.7 EXF76313.1 - 1.9 7.9 7.2 2.2 7.6 5.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF2360 PF10152.4 EXF76313.1 - 2.6 8.3 5.8 3.5 7.9 4.0 1.2 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) HgmA PF04209.8 EXF76314.1 - 3.7e-120 401.1 0.0 4.4e-120 400.9 0.0 1.1 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase RibD_C PF01872.12 EXF76315.1 - 1.3e-37 129.3 0.0 1.5e-37 129.1 0.0 1.0 1 0 0 1 1 1 1 RibD C-terminal domain Transp_cyt_pur PF02133.10 EXF76316.1 - 7e-27 94.0 26.3 1.8e-26 92.7 18.2 1.6 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin p450 PF00067.17 EXF76317.1 - 1.1e-60 205.5 0.0 1.4e-60 205.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PfkB PF00294.19 EXF76318.1 - 1.1e-53 182.3 0.7 1.3e-53 182.1 0.5 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DDDD PF10161.4 EXF76319.1 - 0.17 11.5 0.3 1.5 8.5 0.0 2.3 1 1 1 2 2 2 0 Putative mitochondrial precursor protein UQ_con PF00179.21 EXF76320.1 - 1.2e-09 37.6 0.0 2e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BRE PF06113.7 EXF76320.1 - 0.012 14.6 0.1 0.017 14.1 0.1 1.1 1 0 0 1 1 1 0 Brain and reproductive organ-expressed protein (BRE) RWD PF05773.17 EXF76320.1 - 0.15 11.9 0.1 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 RWD domain DUF1014 PF06244.7 EXF76321.1 - 4.6e-22 78.5 6.0 1.1e-21 77.3 4.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1014) DUF4552 PF15089.1 EXF76321.1 - 0.0075 15.2 0.1 0.01 14.8 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4552) MFS_1 PF07690.11 EXF76322.1 - 9.3e-39 133.1 11.9 9.3e-39 133.1 8.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF76322.1 - 5.2e-12 45.0 2.9 5.2e-12 45.0 2.0 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EXF76322.1 - 7.8e-05 21.2 20.4 0.00065 18.2 1.5 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 EXF76322.1 - 0.88 7.6 7.1 0.028 12.5 0.3 1.9 3 0 0 3 3 3 0 Transmembrane secretion effector Fungal_trans PF04082.13 EXF76323.1 - 1.9e-32 112.1 0.0 2.8e-32 111.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF76323.1 - 5.2e-09 35.8 9.5 8.2e-09 35.2 6.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_Maf PF03131.12 EXF76324.1 - 3.9e-08 33.4 13.3 1.1e-07 32.0 9.2 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_1 PF00170.16 EXF76324.1 - 6.2e-08 32.4 15.0 6.2e-08 32.4 10.4 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EXF76324.1 - 0.0012 18.6 20.3 0.0066 16.2 13.0 2.8 2 1 0 2 2 2 1 Basic region leucine zipper Endotoxin_N PF03945.9 EXF76324.1 - 0.055 12.8 4.4 0.1 11.9 3.0 1.4 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain V_ATPase_I PF01496.14 EXF76324.1 - 1 7.1 8.2 1.5 6.5 5.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF342 PF03961.8 EXF76324.1 - 2.1 6.6 10.2 3.2 6.0 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) GBP_C PF02841.9 EXF76324.1 - 3.6 6.6 17.6 7.7 5.6 12.2 1.5 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain IncA PF04156.9 EXF76324.1 - 3.9 7.0 15.9 11 5.6 11.0 1.7 1 0 0 1 1 1 0 IncA protein Glyco_transf_15 PF01793.11 EXF76324.1 - 8.1 5.2 8.2 15 4.3 5.6 1.5 1 1 0 1 1 1 0 Glycolipid 2-alpha-mannosyltransferase Mob1_phocein PF03637.12 EXF76325.1 - 5.6e-39 133.5 1.5 1.3e-20 73.7 0.0 2.2 2 0 0 2 2 2 2 Mob1/phocein family Leo1 PF04004.8 EXF76326.1 - 1.2e-29 103.2 0.0 2.4e-29 102.2 0.0 1.5 1 0 0 1 1 1 1 Leo1-like protein tRNA_deacylase PF04414.7 EXF76326.1 - 0.043 12.9 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 D-aminoacyl-tRNA deacylase DUF3336 PF11815.3 EXF76327.1 - 1.4e-36 125.1 0.2 3.7e-36 123.7 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EXF76327.1 - 2.9e-14 53.4 0.8 7.4e-14 52.1 0.1 2.0 2 0 0 2 2 2 1 Patatin-like phospholipase Lipase_GDSL_2 PF13472.1 EXF76329.1 - 2.1e-19 70.3 2.6 4.2e-19 69.3 1.8 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EXF76329.1 - 1e-15 58.2 0.3 1.1e-14 54.8 0.7 2.2 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase VWA_3 PF13768.1 EXF76329.1 - 0.016 14.8 0.0 0.071 12.7 0.0 2.0 2 0 0 2 2 2 0 von Willebrand factor type A domain Ferritin_2 PF13668.1 EXF76330.1 - 7.5e-45 152.2 0.1 1.2e-44 151.5 0.1 1.4 1 0 0 1 1 1 1 Ferritin-like domain YoaP PF14268.1 EXF76330.1 - 0.0051 16.0 0.2 0.011 14.9 0.1 1.5 1 0 0 1 1 1 1 YoaP-like FMN_dh PF01070.13 EXF76331.1 - 3.4e-122 407.7 0.0 3.9e-122 407.5 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EXF76331.1 - 1.7e-05 23.9 0.4 2.4e-05 23.4 0.3 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EXF76331.1 - 0.0002 20.3 1.1 0.00054 18.9 0.3 1.8 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.9 EXF76331.1 - 0.0026 16.8 0.9 0.087 11.8 0.4 2.4 3 0 0 3 3 3 1 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EXF76331.1 - 0.0043 16.3 0.7 0.028 13.6 0.3 2.0 1 1 1 2 2 2 1 Histidine biosynthesis protein NMO PF03060.10 EXF76331.1 - 0.071 12.2 2.5 0.11 11.6 1.7 1.2 1 0 0 1 1 1 0 Nitronate monooxygenase IGPS PF00218.16 EXF76331.1 - 0.2 10.6 0.2 0.47 9.4 0.2 1.5 1 1 0 1 1 1 0 Indole-3-glycerol phosphate synthase Sld5 PF05916.6 EXF76332.1 - 2e-06 28.0 0.1 3.1e-06 27.4 0.1 1.4 1 0 0 1 1 1 1 GINS complex protein Sua5_yciO_yrdC PF01300.13 EXF76333.1 - 3.5e-54 182.7 0.0 5.6e-54 182.1 0.0 1.3 1 0 0 1 1 1 1 Telomere recombination SUA5 PF03481.8 EXF76333.1 - 1.2e-25 89.9 0.0 3.1e-25 88.6 0.0 1.7 1 1 0 1 1 1 1 Putative GTP-binding controlling metal-binding Clat_adaptor_s PF01217.15 EXF76334.1 - 3.2e-17 62.5 1.3 1.5e-16 60.4 0.9 1.8 1 1 0 1 1 1 1 Clathrin adaptor complex small chain MCM PF00493.18 EXF76335.1 - 1.2e-139 464.7 0.0 1.7e-139 464.2 0.0 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EXF76335.1 - 1.2e-22 80.7 0.0 5.8e-22 78.4 0.0 2.2 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EXF76335.1 - 2.1e-05 23.7 0.0 0.0004 19.6 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EXF76335.1 - 4.6e-05 23.1 0.1 0.0003 20.5 0.0 2.5 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EXF76335.1 - 0.0017 17.9 0.0 0.0061 16.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EXF76335.1 - 0.11 12.0 0.2 3 7.2 0.0 2.8 3 0 0 3 3 3 0 Sigma-54 interaction domain Methyltransf_23 PF13489.1 EXF76336.1 - 7.6e-16 58.2 0.0 1.2e-15 57.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF76336.1 - 1e-07 32.5 0.0 0.00096 19.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 EXF76336.1 - 4.6e-05 23.0 0.0 0.028 13.9 0.0 2.6 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EXF76336.1 - 0.03 14.7 0.0 0.2 12.1 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EXF76336.1 - 0.077 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 EXF76336.1 - 0.098 11.7 0.0 17 4.4 0.0 2.6 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family Cys_Met_Meta_PP PF01053.15 EXF76337.1 - 3.1e-26 91.5 0.0 5.4e-26 90.7 0.0 1.3 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EXF76337.1 - 0.00026 20.0 0.0 0.00043 19.3 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II ADK PF00406.17 EXF76338.1 - 6.7e-45 152.6 0.0 8.7e-45 152.2 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EXF76338.1 - 8.3e-06 26.1 0.0 1.4e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EXF76338.1 - 9.2e-06 26.4 0.0 1.5e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EXF76338.1 - 2.2e-05 24.3 0.0 7.9e-05 22.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EXF76338.1 - 0.0027 17.1 0.1 1.3 8.3 0.0 2.2 2 0 0 2 2 2 2 Thymidylate kinase Sfi1_C PF10638.4 EXF76338.1 - 0.098 13.0 3.9 0.44 10.9 0.4 2.5 2 0 0 2 2 2 0 Spindle body associated protein C-terminus AAA_19 PF13245.1 EXF76338.1 - 0.11 12.2 0.3 0.98 9.2 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain PCI PF01399.22 EXF76339.1 - 4.8e-15 55.7 0.2 2.6e-14 53.3 0.0 2.3 3 0 0 3 3 3 1 PCI domain FHA PF00498.21 EXF76340.1 - 2.4e-08 33.9 0.1 5.6e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 FHA domain Pkinase PF00069.20 EXF76340.1 - 0.0034 16.5 0.0 0.0052 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain ArfGap PF01412.13 EXF76341.1 - 2.4e-33 114.3 0.3 9.2e-33 112.5 0.0 2.2 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 EXF76341.1 - 1.4e-12 47.7 0.2 5e-12 45.9 0.2 2.0 1 0 0 1 1 1 1 PH domain EMP24_GP25L PF01105.19 EXF76341.1 - 0.051 13.3 4.1 0.51 10.0 1.3 2.5 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF972 PF06156.8 EXF76341.1 - 0.11 12.8 1.9 17 5.8 0.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Syntaxin_2 PF14523.1 EXF76341.1 - 0.17 11.9 3.9 3.9 7.5 0.1 2.8 2 0 0 2 2 2 0 Syntaxin-like protein Prominin PF05478.6 EXF76341.1 - 0.24 8.8 0.6 0.43 8.0 0.4 1.3 1 0 0 1 1 1 0 Prominin ATP-synt_E PF05680.7 EXF76341.1 - 0.93 9.4 6.1 0.79 9.7 0.1 2.7 2 0 0 2 2 2 0 ATP synthase E chain DUF3708 PF12501.3 EXF76341.1 - 2.6 7.8 3.4 1.4 8.7 0.2 2.0 2 0 0 2 2 2 0 Phosphate ATP-binding cassette transporter PH_9 PF15410.1 EXF76341.1 - 6.7 6.9 7.7 1.3 9.1 0.7 3.0 3 1 0 3 3 3 0 Pleckstrin homology domain Membr_traf_MHD PF10540.4 EXF76342.1 - 1.1e-22 80.2 0.1 4.6e-22 78.2 0.0 2.1 1 0 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain C2 PF00168.25 EXF76342.1 - 7.8e-18 64.1 0.1 4.4e-17 61.6 0.0 2.3 2 0 0 2 2 2 1 C2 domain BPD_transp_1 PF00528.17 EXF76342.1 - 0.35 10.3 0.0 0.58 9.6 0.0 1.3 1 0 0 1 1 1 0 Binding-protein-dependent transport system inner membrane component Astacin PF01400.19 EXF76343.1 - 3e-35 121.3 0.0 3.3e-34 117.9 0.0 2.1 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.19 EXF76343.1 - 0.0034 17.1 0.3 0.13 11.9 0.1 2.6 3 0 0 3 3 3 1 Matrixin Ecl1 PF12855.2 EXF76345.1 - 2.3e-07 30.0 0.7 2.3e-07 30.0 0.5 2.1 3 0 0 3 3 3 1 Life-span regulatory factor zf-MYND PF01753.13 EXF76345.1 - 0.04 13.8 2.1 0.072 12.9 1.4 1.4 1 0 0 1 1 1 0 MYND finger Metallothio_Pro PF02069.11 EXF76345.1 - 0.073 12.8 0.7 0.2 11.4 0.1 1.9 2 0 0 2 2 2 0 Prokaryotic metallothionein DUF2475 PF10629.4 EXF76345.1 - 1.6 9.0 6.4 3.8 7.8 2.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2475) Terpene_synth_C PF03936.11 EXF76346.1 - 2.2e-10 40.2 0.0 3.2e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Redoxin PF08534.5 EXF76347.1 - 7.6e-26 90.3 0.0 1.6e-25 89.3 0.0 1.5 1 0 0 1 1 1 1 Redoxin IBR PF01485.16 EXF76347.1 - 5.2e-21 74.2 43.5 2.8e-10 39.9 3.2 4.5 3 1 1 4 4 4 3 IBR domain zf-RING_2 PF13639.1 EXF76347.1 - 2.6e-06 27.1 39.9 4e-05 23.3 3.5 3.6 2 1 1 3 3 3 3 Ring finger domain zf-C3HC4 PF00097.20 EXF76347.1 - 9.6e-06 25.1 39.9 0.00023 20.7 3.9 4.3 3 1 1 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EXF76347.1 - 2.2e-05 24.3 7.2 2.2e-05 24.3 5.0 4.4 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EXF76347.1 - 0.0075 15.9 7.6 0.0075 15.9 5.2 3.6 3 1 0 3 3 3 2 zinc-RING finger domain UN_NPL4 PF11543.3 EXF76347.1 - 0.029 14.6 0.0 0.065 13.5 0.0 1.6 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 zf-C3HC4_4 PF15227.1 EXF76347.1 - 1.3 9.0 33.4 0.72 9.7 3.5 4.3 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING XPG_I PF00867.13 EXF76348.1 - 1.9e-25 88.7 0.0 4.4e-25 87.5 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EXF76348.1 - 1.4e-22 79.8 0.0 3.3e-22 78.6 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.2 EXF76348.1 - 0.00091 18.7 0.6 0.0019 17.7 0.0 1.8 2 0 0 2 2 2 1 XPG domain containing 5_3_exonuc PF01367.15 EXF76348.1 - 0.0015 18.7 0.0 0.0069 16.5 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.2 EXF76348.1 - 0.078 12.8 0.0 0.25 11.2 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF2962 PF11176.3 EXF76349.1 - 1.9e-41 141.1 2.7 2.2e-41 141.0 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2962) IncFII_repA PF02387.10 EXF76349.1 - 5.7 6.0 6.8 14 4.7 0.9 2.0 1 1 1 2 2 2 0 IncFII RepA protein family MAM33 PF02330.11 EXF76350.1 - 1.4e-30 106.6 1.7 8e-29 100.8 1.2 2.1 1 1 0 1 1 1 1 Mitochondrial glycoprotein Pil1 PF13805.1 EXF76350.1 - 0.017 14.2 0.1 0.024 13.7 0.1 1.3 1 0 0 1 1 1 0 Eisosome component PIL1 Lyase_aromatic PF00221.14 EXF76351.1 - 3.9e-162 539.9 8.9 4.8e-162 539.6 6.1 1.1 1 0 0 1 1 1 1 Aromatic amino acid lyase Methyltransf_31 PF13847.1 EXF76352.1 - 1.9e-15 56.7 0.0 4.2e-15 55.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF76352.1 - 1.4e-13 50.9 0.0 2.1e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF76352.1 - 9.5e-12 45.2 0.0 1.5e-11 44.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF76352.1 - 1.9e-11 44.2 0.0 3.5e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF76352.1 - 2.6e-09 37.6 0.0 8.7e-09 35.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF76352.1 - 1.6e-07 31.6 0.0 3.6e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF76352.1 - 6.5e-07 29.3 0.0 1.2e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EXF76352.1 - 5.5e-05 22.4 0.0 0.00014 21.1 0.0 1.6 2 0 0 2 2 2 1 O-methyltransferase MTS PF05175.9 EXF76352.1 - 5.9e-05 22.5 0.0 9.3e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 EXF76352.1 - 0.00014 21.3 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW RrnaAD PF00398.15 EXF76352.1 - 0.00018 20.6 0.0 0.00029 19.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase FtsJ PF01728.14 EXF76352.1 - 0.00083 19.3 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 EXF76352.1 - 0.00088 18.3 0.0 0.0026 16.8 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.15 EXF76352.1 - 0.035 13.2 0.0 0.085 11.9 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EXF76352.1 - 0.053 13.0 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EXF76352.1 - 0.06 12.4 0.0 0.098 11.7 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Scytalone_dh PF02982.9 EXF76353.1 - 3.9e-82 273.5 0.4 4.4e-82 273.3 0.3 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EXF76353.1 - 4.4e-08 33.0 0.1 6.3e-08 32.5 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain CAP PF00188.21 EXF76354.1 - 1e-23 84.1 2.6 1e-23 84.1 1.8 1.5 2 0 0 2 2 2 1 Cysteine-rich secretory protein family MSP1_C PF07462.6 EXF76354.1 - 8.8 4.5 8.3 11 4.2 5.7 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Ecm29 PF13001.2 EXF76356.1 - 0.1 11.1 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Proteasome stabiliser Oxysterol_BP PF01237.13 EXF76357.1 - 3.2e-52 177.1 0.0 5.8e-42 143.4 0.0 2.2 2 0 0 2 2 2 2 Oxysterol-binding protein Apq12 PF12716.2 EXF76358.1 - 3.7e-09 36.1 10.2 6.6e-09 35.3 7.0 1.4 1 0 0 1 1 1 1 Nuclear pore assembly and biogenesis Antimicrobial_7 PF08102.6 EXF76358.1 - 0.0016 18.3 0.4 0.13 12.3 0.0 2.6 3 0 0 3 3 3 2 Scorpion antimicrobial peptide ATP_bind_1 PF03029.12 EXF76359.1 - 2.5e-70 236.7 0.0 3.1e-70 236.4 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EXF76359.1 - 4.9e-06 27.3 0.0 1.3e-05 25.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EXF76359.1 - 0.00098 19.0 0.0 0.0021 17.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EXF76359.1 - 0.0031 17.6 0.0 0.0074 16.4 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 EXF76359.1 - 0.0037 17.3 0.0 0.0068 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EXF76359.1 - 0.0041 16.8 0.0 0.0077 15.9 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EXF76359.1 - 0.0045 16.8 0.0 0.0075 16.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EXF76359.1 - 0.011 15.2 0.0 0.043 13.2 0.0 1.9 2 1 1 3 3 2 0 AAA-like domain GTP_EFTU PF00009.22 EXF76359.1 - 0.017 14.5 0.0 4.8 6.5 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EXF76359.1 - 0.018 14.5 0.0 0.032 13.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 EXF76359.1 - 0.019 14.5 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 EXF76359.1 - 0.028 14.3 0.1 0.13 12.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 EXF76359.1 - 0.028 13.3 0.0 0.039 12.9 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain PPV_E1_C PF00519.12 EXF76359.1 - 0.044 12.3 0.0 0.068 11.7 0.0 1.2 1 0 0 1 1 1 0 Papillomavirus helicase AAA_16 PF13191.1 EXF76359.1 - 0.045 13.7 0.0 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.18 EXF76359.1 - 0.053 13.4 0.0 0.11 12.4 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase SRP54 PF00448.17 EXF76359.1 - 0.063 12.7 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 EXF76359.1 - 0.064 13.5 0.0 0.13 12.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter cobW PF02492.14 EXF76359.1 - 0.08 12.3 0.1 5.1 6.5 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 EXF76359.1 - 0.092 12.1 0.0 0.22 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 EXF76359.1 - 0.095 11.6 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Septin NACHT PF05729.7 EXF76359.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 EXF76359.1 - 0.1 12.3 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain PduV-EutP PF10662.4 EXF76359.1 - 0.11 12.0 0.0 1.3 8.5 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IstB_IS21 PF01695.12 EXF76359.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 EXF76359.1 - 0.13 12.5 0.0 0.42 10.9 0.0 2.0 3 0 0 3 3 1 0 AAA domain S-AdoMet_synt_C PF02773.11 EXF76360.1 - 7.2e-75 249.2 0.2 1.3e-74 248.4 0.2 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EXF76360.1 - 9.8e-48 161.0 0.0 1.7e-47 160.2 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EXF76360.1 - 7.4e-42 141.6 0.3 2.1e-41 140.2 0.0 1.9 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain TOH_N PF12549.3 EXF76361.1 - 0.0021 17.5 2.6 0.0096 15.4 1.8 2.1 1 0 0 1 1 1 1 Tyrosine hydroxylase N terminal PI-PLC-X PF00388.14 EXF76364.1 - 2e-11 43.4 0.0 3e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain MaoC_dehydratas PF01575.14 EXF76367.1 - 2.6e-20 72.0 0.0 5.2e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain CAP_GLY PF01302.20 EXF76367.1 - 4.2e-13 48.7 0.1 8.8e-13 47.7 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.1 EXF76367.1 - 9.9e-13 47.6 4.2 1e-05 25.1 1.6 3.9 4 0 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.2 EXF76367.1 - 1.8e-12 46.6 1.0 7.5e-05 22.2 0.5 5.0 4 1 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EXF76367.1 - 1.6e-06 27.2 2.1 19 5.7 0.0 6.5 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.1 EXF76367.1 - 0.00052 19.8 0.4 40 4.7 0.0 5.6 6 0 0 6 6 6 0 Leucine Rich repeat MaoC_dehydrat_N PF13452.1 EXF76367.1 - 0.00055 19.7 0.0 0.0063 16.3 0.0 2.3 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase LRR_7 PF13504.1 EXF76367.1 - 0.00061 19.5 2.1 72 4.2 0.1 6.2 7 0 0 7 7 7 0 Leucine rich repeat zf-CCCH PF00642.19 EXF76367.1 - 0.022 14.4 3.1 0.047 13.3 2.2 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Aldo_ket_red PF00248.16 EXF76368.1 - 2.7e-58 197.0 0.0 3e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.27 EXF76369.1 - 5.4e-19 67.3 6.0 5.1e-08 32.5 0.1 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ATP-synt_E PF05680.7 EXF76370.1 - 5.8e-24 83.8 0.1 6.1e-24 83.7 0.1 1.0 1 0 0 1 1 1 1 ATP synthase E chain ABC_trans_N PF14510.1 EXF76370.1 - 0.018 15.0 0.1 0.025 14.6 0.1 1.3 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal CotJB PF12652.2 EXF76370.1 - 0.039 14.0 0.2 0.057 13.4 0.1 1.3 1 0 0 1 1 1 0 CotJB protein Drf_GBD PF06371.8 EXF76370.1 - 0.05 12.9 0.0 0.052 12.9 0.0 1.1 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain DUF3186 PF11382.3 EXF76370.1 - 0.055 12.5 0.5 0.07 12.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) XRCC4 PF06632.7 EXF76370.1 - 0.066 12.0 0.6 0.078 11.8 0.4 1.0 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 SpoOE-like PF09388.5 EXF76370.1 - 0.15 11.5 0.2 0.42 10.1 0.0 1.8 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein STT3 PF02516.9 EXF76371.1 - 6.1e-132 441.0 38.8 5.4e-127 424.6 25.1 2.1 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit Dpy19 PF10034.4 EXF76371.1 - 0.0045 15.2 0.0 0.013 13.7 0.0 1.7 1 1 0 1 1 1 1 Q-cell neuroblast polarisation Rcd1 PF04078.8 EXF76371.1 - 0.07 11.9 0.0 0.15 10.8 0.0 1.5 1 0 0 1 1 1 0 Cell differentiation family, Rcd1-like DUF2752 PF10825.3 EXF76372.1 - 0.042 13.8 3.5 1.8 8.6 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2752) VSP PF03302.8 EXF76373.1 - 9.6e-05 21.1 0.2 0.00014 20.6 0.1 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein RCR PF12273.3 EXF76373.1 - 0.0014 19.2 1.8 0.0036 17.8 0.2 2.2 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red Podoplanin PF05808.6 EXF76373.1 - 0.0081 15.7 0.1 0.0081 15.7 0.1 2.9 3 1 1 4 4 4 1 Podoplanin Yip1 PF04893.12 EXF76373.1 - 0.016 14.7 0.1 0.026 14.0 0.1 1.2 1 0 0 1 1 1 0 Yip1 domain Zip PF02535.17 EXF76373.1 - 0.06 12.3 0.8 0.095 11.6 0.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1183 PF06682.7 EXF76373.1 - 0.1 12.1 9.6 0.099 12.2 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) YebO PF13974.1 EXF76373.1 - 0.83 9.4 4.9 0.12 12.1 0.5 1.7 2 0 0 2 2 2 0 YebO-like protein Pex14_N PF04695.8 EXF76373.1 - 1.8 8.6 9.2 0.55 10.2 0.4 3.0 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.8 EXF76374.1 - 9.5e-78 262.7 3.5 1.3e-77 262.2 2.4 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4551 PF15087.1 EXF76374.1 - 0.18 10.1 0.7 0.24 9.7 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) WD40 PF00400.27 EXF76375.1 - 3.1e-25 87.1 17.3 1.7e-06 27.6 0.1 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EXF76375.1 - 1.2e-06 28.3 0.3 0.0002 21.1 0.1 2.6 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Apc4_WD40 PF12894.2 EXF76375.1 - 0.026 14.0 0.0 0.55 9.7 0.0 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Kelch_4 PF13418.1 EXF76376.1 - 5.2e-23 80.5 10.8 9.4e-09 34.9 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EXF76376.1 - 9.5e-23 79.7 3.3 8.4e-07 28.8 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.1 EXF76376.1 - 1.4e-21 75.6 4.7 7.2e-05 22.7 0.0 5.7 4 1 2 6 6 6 4 Kelch motif Kelch_1 PF01344.20 EXF76376.1 - 6.6e-20 70.3 0.8 0.00014 21.3 0.0 4.6 4 0 0 4 4 4 4 Kelch motif Kelch_3 PF13415.1 EXF76376.1 - 5e-18 64.7 8.0 9.2e-07 28.8 0.0 5.5 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.10 EXF76376.1 - 6.7e-16 57.3 5.2 0.0016 18.1 0.0 4.8 4 0 0 4 4 4 4 Kelch motif BTB PF00651.26 EXF76376.1 - 1.2e-09 38.1 0.0 2.1e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 EXF76376.1 - 0.046 13.5 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 BTB And C-terminal Kelch zf-C2H2_4 PF13894.1 EXF76377.1 - 0.00046 20.3 6.8 0.19 12.1 0.1 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EXF76377.1 - 0.00078 19.6 8.7 0.024 14.9 0.2 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EXF76377.1 - 0.0088 16.1 0.6 0.076 13.1 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EXF76377.1 - 0.0096 16.2 7.7 0.17 12.3 0.3 3.4 3 0 0 3 3 3 2 Zinc finger, C2H2 type HIG_1_N PF04588.8 EXF76378.1 - 1.1e-05 25.0 2.8 2.1e-05 24.1 2.0 1.5 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DUF3617 PF12276.3 EXF76378.1 - 0.015 14.7 0.1 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3617) Kelch_4 PF13418.1 EXF76379.1 - 1.3e-44 149.7 17.8 3e-10 39.7 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EXF76379.1 - 7.1e-44 147.0 22.4 1.6e-09 37.6 0.0 7.1 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EXF76379.1 - 6.7e-41 137.6 15.9 1.2e-06 28.2 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 EXF76379.1 - 2.8e-40 135.6 12.5 1.7e-08 33.8 0.4 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EXF76379.1 - 3.6e-35 118.6 15.1 2.2e-06 27.6 0.0 6.3 4 2 2 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EXF76379.1 - 8.4e-32 107.7 16.0 7.4e-07 28.6 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Ank_2 PF12796.2 EXF76380.1 - 1.3e-54 182.5 3.2 3.1e-11 43.4 0.1 9.9 5 3 4 9 9 9 7 Ankyrin repeats (3 copies) Ank PF00023.25 EXF76380.1 - 6.7e-38 126.6 23.8 0.003 17.3 0.0 17.0 17 0 0 17 17 17 11 Ankyrin repeat Ank_4 PF13637.1 EXF76380.1 - 1.5e-27 95.4 15.5 3.1e-07 30.7 0.1 11.9 9 4 5 14 14 14 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF76380.1 - 7.2e-25 86.4 15.2 4.5e-06 26.7 0.1 11.5 8 3 4 12 12 12 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF76380.1 - 3.4e-19 66.9 13.0 0.016 15.4 0.0 13.3 13 0 0 13 13 13 4 Ankyrin repeat NACHT PF05729.7 EXF76380.1 - 2.3e-08 33.9 0.0 5.4e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EXF76380.1 - 0.0004 20.4 0.1 0.0021 18.0 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EXF76380.1 - 0.0091 15.4 0.0 0.022 14.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EXF76380.1 - 0.011 15.2 0.0 0.031 13.7 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_22 PF13401.1 EXF76380.1 - 0.052 13.6 0.0 0.2 11.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EXF76380.1 - 0.098 12.0 0.0 0.41 10.0 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain ATP-synt_ab PF00006.20 EXF76380.1 - 0.3 10.5 0.0 0.82 9.1 0.0 1.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF1479 PF07350.7 EXF76381.1 - 7.6e-159 528.6 0.0 1.2e-158 528.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) HHH PF00633.18 EXF76381.1 - 0.066 12.9 0.3 0.17 11.6 0.2 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif zf-met2 PF12907.2 EXF76382.1 - 4e-17 61.8 2.3 5.8e-17 61.3 1.6 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 EXF76382.1 - 1.9e-06 28.4 8.8 1.9e-06 28.4 6.1 1.5 2 0 0 2 2 2 1 4F5 protein family DIOX_N PF14226.1 EXF76383.1 - 4.5e-25 88.4 0.0 6.4e-24 84.7 0.0 2.5 2 1 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EXF76383.1 - 1.1e-13 51.3 0.0 1.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily UPF0556 PF10572.4 EXF76383.1 - 0.074 12.2 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0556 WD40 PF00400.27 EXF76384.1 - 1.8e-11 43.4 5.3 0.00018 21.2 0.2 5.5 7 0 0 7 7 7 3 WD domain, G-beta repeat PQQ PF01011.16 EXF76384.1 - 0.012 15.1 0.5 0.1 12.1 0.0 3.0 2 0 0 2 2 2 0 PQQ enzyme repeat PQQ_3 PF13570.1 EXF76384.1 - 0.21 11.8 1.5 3 8.2 0.2 3.8 4 0 0 4 4 4 0 PQQ-like domain RNA_pol_N PF01194.12 EXF76385.1 - 1.9e-29 101.4 1.0 2.5e-29 101.0 0.7 1.2 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Methyltransf_16 PF10294.4 EXF76388.1 - 1.3e-17 63.8 0.0 2.4e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EXF76388.1 - 0.0036 16.7 0.0 0.0079 15.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EXF76388.1 - 0.0055 17.2 0.1 0.013 16.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF76388.1 - 0.034 13.8 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EXF76388.1 - 0.034 13.2 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EXF76388.1 - 0.054 13.5 0.0 0.12 12.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain EF1G PF00647.14 EXF76390.1 - 0.53 10.0 2.6 0.65 9.7 0.6 1.9 2 0 0 2 2 2 0 Elongation factor 1 gamma, conserved domain Dynein_light PF01221.13 EXF76393.1 - 4.3e-41 138.8 1.3 4.9e-41 138.6 0.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 RRM_1 PF00076.17 EXF76394.1 - 2.2e-77 254.6 2.1 1.4e-18 66.3 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF76394.1 - 5e-67 221.8 1.3 2.9e-16 59.1 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF76394.1 - 2.9e-38 129.4 0.0 1.6e-09 37.4 0.0 5.3 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EXF76394.1 - 7.7e-07 28.7 1.1 0.51 10.1 0.1 5.5 5 1 0 5 5 5 2 Limkain b1 Nup35_RRM_2 PF14605.1 EXF76394.1 - 6.8e-06 25.7 0.0 2.1 8.1 0.0 4.3 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EXF76394.1 - 1.1e-05 25.1 4.1 0.72 9.7 0.0 5.8 6 0 0 6 6 6 1 RNA binding motif RRM_2 PF04059.7 EXF76394.1 - 0.034 14.1 0.0 1.4 8.9 0.0 3.1 3 0 0 3 3 3 0 RNA recognition motif 2 TEA PF01285.13 EXF76395.1 - 6.5e-19 68.4 1.2 1.2e-18 67.5 0.0 2.0 2 0 0 2 2 2 1 TEA/ATTS domain family Pro_isomerase PF00160.16 EXF76397.1 - 4.2e-47 160.2 0.6 4.8e-47 160.0 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thioredoxin_3 PF13192.1 EXF76397.1 - 0.056 13.2 0.0 0.088 12.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin domain zf-RING_2 PF13639.1 EXF76398.1 - 1.3e-12 47.3 6.9 2e-12 46.7 4.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EXF76398.1 - 4.8e-08 32.9 3.3 1e-07 31.9 2.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EXF76398.1 - 8.4e-08 31.7 4.2 1.3e-07 31.0 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EXF76398.1 - 2e-05 24.2 4.0 3.1e-05 23.6 2.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EXF76398.1 - 3.9e-05 23.5 5.9 6.2e-05 22.9 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EXF76398.1 - 0.0001 21.8 2.6 0.00016 21.3 1.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Cut8_N PF14482.1 EXF76398.1 - 0.0013 18.7 0.6 0.6 10.1 0.4 3.1 2 0 0 2 2 2 1 Cut8 proteasome-binding domain zf-Apc11 PF12861.2 EXF76398.1 - 0.0014 18.4 1.7 0.0027 17.4 1.2 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EXF76398.1 - 0.0082 15.7 6.4 0.013 15.0 4.5 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain SAGA-Tad1 PF12767.2 EXF76398.1 - 0.018 14.7 0.4 0.018 14.7 0.3 2.1 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit PHD PF00628.24 EXF76398.1 - 0.14 11.8 5.7 0.24 11.1 3.9 1.4 1 0 0 1 1 1 0 PHD-finger Neur_chan_memb PF02932.11 EXF76398.1 - 0.15 11.9 0.1 0.41 10.4 0.0 1.8 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FANCL_C PF11793.3 EXF76398.1 - 0.38 10.7 3.2 0.95 9.4 2.2 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EXF76398.1 - 0.62 9.9 4.9 1.2 9.0 3.4 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 EXF76398.1 - 1.7 8.7 5.7 3.2 7.8 3.9 1.5 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 EXF76398.1 - 3.7 7.3 8.4 3.3 7.5 3.8 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 DUF3752 PF12572.3 EXF76399.1 - 6.7e-40 136.6 9.4 6.7e-40 136.6 6.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3752) Vps8 PF12816.2 EXF76400.1 - 2.7e-75 251.9 0.0 4.7e-75 251.1 0.0 1.4 1 0 0 1 1 1 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EXF76400.1 - 3.7e-05 23.3 0.0 0.26 10.8 0.0 3.2 3 0 0 3 3 3 2 Region in Clathrin and VPS zf-RING_2 PF13639.1 EXF76400.1 - 0.001 18.8 0.1 0.0025 17.5 0.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EXF76400.1 - 0.014 15.1 2.1 0.019 14.7 0.0 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EXF76400.1 - 0.06 13.3 0.1 0.06 13.3 0.0 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RhgB_N PF09284.5 EXF76401.1 - 1.3e-67 227.7 1.8 1.3e-67 227.7 1.2 1.7 2 0 0 2 2 2 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 EXF76401.1 - 7e-45 152.6 0.1 7e-45 152.6 0.1 2.4 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EXF76401.1 - 6e-16 58.3 2.9 7.1e-16 58.1 0.9 2.1 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EXF76401.1 - 0.00095 19.1 0.4 0.0032 17.4 0.3 1.9 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain UDG PF03167.14 EXF76402.1 - 2.7e-14 52.9 0.0 3.6e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily LigB PF02900.13 EXF76403.1 - 2.6e-41 141.4 0.0 3.1e-41 141.1 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Peptidase_S8 PF00082.17 EXF76404.1 - 5.6e-54 183.2 10.2 9.4e-54 182.4 7.0 1.3 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EXF76404.1 - 1.4e-21 76.7 0.4 3.7e-21 75.4 0.3 1.8 1 0 0 1 1 1 1 Peptidase inhibitor I9 Beach PF02138.13 EXF76405.1 - 5.1e-110 367.1 0.0 8.8e-110 366.3 0.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EXF76405.1 - 5.3e-11 42.2 0.0 1.2e-10 41.1 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 EXF76405.1 - 6.3e-11 42.7 0.0 1.4e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.27 EXF76405.1 - 8.6e-09 34.9 5.3 0.00015 21.5 0.1 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Inhibitor_I71 PF12628.2 EXF76406.1 - 0.037 13.7 0.0 0.038 13.6 0.0 1.1 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor DDOST_48kD PF03345.9 EXF76407.1 - 2.6e-168 559.9 0.0 2.9e-168 559.7 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta ABC_tran PF00005.22 EXF76409.1 - 7e-40 136.4 0.0 1.1e-30 106.7 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EXF76409.1 - 3.9e-36 124.9 11.1 5.7e-36 124.3 7.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EXF76409.1 - 2.5e-07 30.1 0.2 0.017 14.3 0.0 3.2 2 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EXF76409.1 - 9.8e-05 22.4 0.0 0.59 10.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain ABC_ATPase PF09818.4 EXF76409.1 - 0.0004 19.0 0.0 0.2 10.1 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF3147 PF11345.3 EXF76409.1 - 0.0011 18.9 0.4 0.0034 17.3 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3147) AAA_22 PF13401.1 EXF76409.1 - 0.0019 18.3 1.1 0.041 14.0 0.8 3.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EXF76409.1 - 0.0025 17.8 0.3 0.0084 16.1 0.2 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.1 EXF76409.1 - 0.0035 16.8 0.0 0.0087 15.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EXF76409.1 - 0.0045 16.1 0.0 0.0085 15.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EXF76409.1 - 0.0053 16.6 0.1 0.91 9.4 0.0 2.8 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.24 EXF76409.1 - 0.0088 16.2 1.9 0.17 12.0 1.3 2.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EXF76409.1 - 0.011 16.5 0.0 0.025 15.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EXF76409.1 - 0.019 14.5 0.0 0.44 10.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EXF76409.1 - 0.073 12.4 0.1 0.29 10.5 0.0 1.9 1 1 0 1 1 1 0 AAA domain IPK PF03770.11 EXF76409.1 - 0.12 12.0 0.0 0.51 9.9 0.0 1.8 1 1 0 1 1 1 0 Inositol polyphosphate kinase adh_short_C2 PF13561.1 EXF76410.1 - 2.4e-29 102.8 0.7 2.7e-29 102.6 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EXF76410.1 - 1.8e-13 50.7 1.2 7.9e-13 48.6 0.6 1.9 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 EXF76410.1 - 3.3e-06 26.8 0.6 4.3e-05 23.2 0.1 2.0 2 0 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 EXF76410.1 - 0.0015 18.2 1.9 0.0031 17.2 1.3 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EXF76410.1 - 0.0054 16.2 0.0 0.48 9.8 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_7 PF13241.1 EXF76410.1 - 0.0073 16.5 0.1 0.025 14.8 0.0 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_10 PF13460.1 EXF76410.1 - 0.016 15.2 1.6 0.037 14.0 1.1 2.0 1 1 0 1 1 1 0 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EXF76410.1 - 0.017 14.2 0.8 0.052 12.6 0.1 2.2 3 0 0 3 3 3 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Abhydrolase_6 PF12697.2 EXF76412.1 - 9.8e-18 64.8 0.0 1.2e-17 64.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF76412.1 - 1.3e-08 34.6 0.1 2.3e-08 33.8 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF76412.1 - 7.1e-08 32.2 0.0 0.0016 18.0 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold ADH_zinc_N PF00107.21 EXF76413.1 - 1.4e-11 44.0 0.0 2.1e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF76413.1 - 5e-05 24.2 0.0 9.2e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase adh_short PF00106.20 EXF76413.1 - 0.01 15.7 0.1 0.016 15.1 0.1 1.2 1 0 0 1 1 1 0 short chain dehydrogenase NAD_binding_10 PF13460.1 EXF76413.1 - 0.018 15.0 0.7 0.027 14.4 0.5 1.3 1 0 0 1 1 1 0 NADH(P)-binding DapB_N PF01113.15 EXF76413.1 - 0.024 14.5 0.4 0.033 14.1 0.3 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.18 EXF76413.1 - 0.083 12.7 0.8 0.55 10.0 0.1 2.1 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Abhydrolase_1 PF00561.15 EXF76415.1 - 7.1e-17 61.7 0.0 3.3e-16 59.5 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EXF76415.1 - 1.7e-11 44.4 3.6 9.6e-11 41.9 2.5 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EXF76415.1 - 0.0014 18.0 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 Putative esterase NUDIX PF00293.23 EXF76416.1 - 7.8e-07 28.8 0.0 1.4e-06 28.0 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain NUDIX PF00293.23 EXF76417.1 - 4.7e-18 65.1 0.2 8.9e-18 64.2 0.0 1.4 2 0 0 2 2 2 1 NUDIX domain SIR2 PF02146.12 EXF76418.1 - 8.2e-57 191.7 0.0 1.2e-56 191.2 0.0 1.3 1 0 0 1 1 1 1 Sir2 family MFS_1 PF07690.11 EXF76418.1 - 5.5e-16 58.2 26.0 5.5e-16 58.2 18.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF342 PF03961.8 EXF76418.1 - 0.022 13.1 0.5 0.042 12.2 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3464 PF11947.3 EXF76418.1 - 0.12 11.8 1.1 1.1 8.7 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) zf-LYAR PF08790.6 EXF76418.1 - 0.23 11.1 0.2 0.46 10.2 0.1 1.5 1 0 0 1 1 1 0 LYAR-type C2HC zinc finger LPAM_1 PF08139.7 EXF76419.1 - 4.9 7.5 6.6 8.5 6.7 4.6 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site FAD_binding_3 PF01494.14 EXF76420.1 - 2e-27 96.1 0.0 9.9e-27 93.9 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EXF76420.1 - 8e-06 25.0 0.6 7.5e-05 21.8 0.4 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EXF76420.1 - 1e-05 24.6 2.4 0.00028 19.9 1.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF76420.1 - 0.00053 19.9 0.4 0.0015 18.4 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EXF76420.1 - 0.00077 19.8 0.5 0.0025 18.1 0.4 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EXF76420.1 - 0.004 16.3 1.9 0.99 8.3 0.0 2.5 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EXF76420.1 - 0.016 14.1 1.3 0.048 12.4 0.4 2.0 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 EXF76420.1 - 0.018 13.9 0.1 0.037 12.8 0.1 1.5 1 1 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EXF76420.1 - 0.034 14.0 0.6 0.076 12.8 0.4 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EXF76420.1 - 0.034 12.7 0.6 0.24 9.9 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 EXF76420.1 - 0.24 11.4 1.4 1.1 9.2 1.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAA_hydrolase PF01557.13 EXF76421.1 - 2.3e-61 207.0 0.0 3.8e-61 206.3 0.0 1.4 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family p450 PF00067.17 EXF76421.1 - 7.1e-59 199.5 0.0 1e-58 198.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 EXF76421.1 - 6.8e-32 111.1 0.1 1.2e-31 110.3 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF76421.1 - 1.2e-15 57.7 0.0 5.3e-14 52.3 0.0 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF76421.1 - 5.9e-14 52.0 0.0 2.4e-13 50.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EXF76421.1 - 2.4e-09 37.0 0.6 0.00027 20.6 0.0 2.7 2 1 1 3 3 3 2 Serine hydrolase Hydrolase_4 PF12146.3 EXF76421.1 - 0.046 13.5 0.0 0.15 11.9 0.0 1.9 2 0 0 2 2 2 0 Putative lysophospholipase Abhydrolase_4 PF08386.5 EXF76421.1 - 0.14 12.0 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein Amidohydro_4 PF13147.1 EXF76422.1 - 7e-21 75.4 0.3 1.5e-20 74.4 0.2 1.5 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EXF76422.1 - 1.6e-20 74.0 0.2 9.1e-20 71.5 0.1 2.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EXF76422.1 - 1.6e-10 40.7 1.5 5.3e-06 25.8 0.4 2.5 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_5 PF13594.1 EXF76422.1 - 1.6e-09 37.4 2.2 3.4e-09 36.4 1.5 1.6 1 0 0 1 1 1 1 Amidohydrolase Fungal_trans_2 PF11951.3 EXF76423.1 - 0.0082 14.7 1.7 0.01 14.4 1.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box-like PF12937.2 EXF76424.1 - 0.064 12.9 0.1 0.62 9.8 0.0 2.3 2 0 0 2 2 2 0 F-box-like PCIF1_WW PF12237.3 EXF76424.1 - 0.15 11.3 0.1 0.25 10.5 0.1 1.3 1 0 0 1 1 1 0 Phosphorylated CTD interacting factor 1 WW domain Amidase PF01425.16 EXF76425.1 - 5.5e-112 374.8 0.2 6.5e-112 374.5 0.2 1.1 1 0 0 1 1 1 1 Amidase PRP38 PF03371.10 EXF76426.1 - 1.2e-58 197.4 0.0 1.6e-58 197.1 0.0 1.1 1 0 0 1 1 1 1 PRP38 family DUF1509 PF07420.6 EXF76426.1 - 0.0034 16.7 2.0 0.0044 16.3 1.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1509) Nucleo_P87 PF07267.6 EXF76427.1 - 0.22 10.1 3.3 0.23 10.1 2.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 CBFD_NFYB_HMF PF00808.18 EXF76428.1 - 2.7e-17 62.5 1.5 4.5e-17 61.8 0.5 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EXF76428.1 - 0.00063 19.8 0.2 0.0015 18.5 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 DUF3656 PF12392.3 EXF76428.1 - 0.01 15.9 0.2 0.013 15.6 0.1 1.2 1 0 0 1 1 1 0 Collagenase BBIP10 PF14777.1 EXF76428.1 - 0.078 12.3 0.3 0.37 10.2 0.0 2.1 2 1 0 2 2 2 0 Cilia BBSome complex subunit 10 Bromo_TP PF07524.8 EXF76428.1 - 0.12 12.0 0.1 0.29 10.9 0.0 1.6 1 1 0 1 1 1 0 Bromodomain associated adh_short PF00106.20 EXF76429.1 - 4e-30 104.9 1.5 5.4e-30 104.5 1.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF76429.1 - 9.6e-18 64.8 0.4 1.3e-17 64.4 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF76429.1 - 1.4e-11 44.3 0.7 2.1e-11 43.8 0.5 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EXF76429.1 - 1.1e-06 28.7 1.1 1.5e-06 28.3 0.8 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF76429.1 - 0.00065 19.1 0.2 0.0012 18.3 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EXF76429.1 - 0.0022 17.2 0.2 0.0034 16.6 0.2 1.3 1 0 0 1 1 1 1 NmrA-like family TrkA_N PF02254.13 EXF76429.1 - 0.043 13.8 0.2 0.14 12.1 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain PP2C_2 PF13672.1 EXF76429.1 - 0.046 13.1 0.3 0.069 12.5 0.2 1.3 1 0 0 1 1 1 0 Protein phosphatase 2C Shikimate_DH PF01488.15 EXF76429.1 - 0.046 13.8 0.5 0.11 12.5 0.1 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 EXF76429.1 - 0.048 13.3 0.0 0.089 12.5 0.0 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.19 EXF76430.1 - 5.8e-41 140.5 0.4 6.8e-41 140.3 0.3 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF76430.1 - 3e-06 27.2 0.0 0.058 13.2 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF76430.1 - 4.4e-05 23.8 0.0 0.045 14.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF76430.1 - 0.0044 17.0 3.5 0.0045 16.9 0.1 2.8 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EXF76430.1 - 0.035 14.1 0.1 0.6 10.1 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF76430.1 - 0.039 12.8 0.0 0.083 11.7 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein HI0933_like PF03486.9 EXF76430.1 - 0.053 11.9 0.0 0.098 11.1 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 EXF76430.1 - 0.071 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EXF76430.1 - 0.078 12.0 0.0 2.6 7.0 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain Saccharop_dh PF03435.13 EXF76430.1 - 0.11 11.4 0.0 0.17 10.7 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_9 PF13454.1 EXF76430.1 - 0.14 11.9 0.3 0.3 10.8 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding CBM_1 PF00734.13 EXF76432.1 - 1.8e-13 49.8 10.0 6.2e-13 48.1 6.9 2.0 1 0 0 1 1 1 1 Fungal cellulose binding domain Reprolysin_4 PF13583.1 EXF76432.1 - 0.033 13.6 0.1 0.067 12.7 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Toxin_7 PF05980.7 EXF76432.1 - 0.035 14.1 2.8 0.066 13.2 1.9 1.5 1 0 0 1 1 1 0 Toxin 7 Reprolysin_2 PF13574.1 EXF76432.1 - 0.04 13.9 0.1 0.096 12.7 0.1 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF1025 PF06262.6 EXF76432.1 - 0.043 13.6 0.1 0.12 12.1 0.1 1.7 2 0 0 2 2 2 0 Possibl zinc metallo-peptidase PmbA_TldD PF01523.11 EXF76432.1 - 0.053 12.7 1.6 0.11 11.7 1.1 1.5 1 0 0 1 1 1 0 Putative modulator of DNA gyrase Reprolysin_3 PF13582.1 EXF76432.1 - 0.14 12.6 0.1 0.14 12.6 0.1 1.9 2 0 0 2 2 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EXF76432.1 - 0.25 10.1 3.5 0.74 8.6 0.2 2.3 2 0 0 2 2 2 0 Peptidase M66 Mito_fiss_reg PF05308.6 EXF76432.1 - 2.6 7.3 10.1 4.7 6.4 7.0 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator PLRV_ORF5 PF01690.12 EXF76432.1 - 3.4 6.7 12.9 5.6 6.0 8.9 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Lamp PF01299.12 EXF76432.1 - 4.5 6.3 9.9 7.3 5.6 6.9 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) p450 PF00067.17 EXF76434.1 - 3.3e-23 81.9 0.0 2.3e-16 59.3 0.0 3.0 1 1 1 2 2 2 2 Cytochrome P450 Ribosomal_S26e PF01283.14 EXF76435.1 - 3.5e-50 169.0 9.2 4e-50 168.8 6.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 EXF76435.1 - 0.049 14.0 1.3 1.1 9.6 0.4 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Zn_ribbon_2 PF12674.2 EXF76435.1 - 0.092 13.1 0.5 7.6 6.9 0.0 2.2 1 1 1 2 2 2 0 Putative zinc ribbon domain Adenylsucc_synt PF00709.16 EXF76436.1 - 1.1e-153 511.9 0.0 1.3e-153 511.6 0.0 1.1 1 0 0 1 1 1 1 Adenylosuccinate synthetase CFEM PF05730.6 EXF76437.1 - 1.2e-08 34.6 6.6 1.2e-08 34.6 4.6 1.7 2 1 0 2 2 2 1 CFEM domain LRR_7 PF13504.1 EXF76438.1 - 0.14 12.4 0.8 7.5 7.2 0.1 3.6 4 0 0 4 4 4 0 Leucine rich repeat Sugar_tr PF00083.19 EXF76439.1 - 5.2e-97 325.2 18.2 6.3e-97 324.9 12.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF76439.1 - 2.8e-15 55.9 27.5 2.8e-15 55.9 19.1 2.4 1 1 0 2 2 2 2 Major Facilitator Superfamily Bac_luciferase PF00296.15 EXF76439.1 - 0.01 15.0 0.8 0.019 14.0 0.6 1.4 1 0 0 1 1 1 0 Luciferase-like monooxygenase adh_short PF00106.20 EXF76440.1 - 1e-28 100.3 6.5 1.3e-28 100.0 4.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF76440.1 - 8.1e-25 87.9 1.0 9.7e-25 87.7 0.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF76440.1 - 1.9e-11 43.9 4.2 2.6e-11 43.5 2.9 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF76440.1 - 0.0074 15.7 0.9 0.015 14.7 0.6 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2188 PF09954.4 EXF76440.1 - 0.042 13.7 2.1 0.074 12.9 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2188) NAD_binding_10 PF13460.1 EXF76440.1 - 0.29 11.0 7.2 10 6.0 5.0 2.1 1 1 0 1 1 1 0 NADH(P)-binding Melibiase PF02065.13 EXF76441.1 - 3.5e-13 49.0 0.0 9.1e-10 37.7 0.0 2.8 2 1 0 2 2 2 2 Melibiase Phage_CP76 PF06892.6 EXF76441.1 - 0.15 11.3 1.4 0.38 10.0 0.1 1.9 1 1 1 2 2 2 0 Phage regulatory protein CII (CP76) Glyco_hydro_61 PF03443.9 EXF76442.1 - 4.9e-64 216.1 0.1 5.8e-64 215.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Spore_SspJ PF09575.5 EXF76444.1 - 0.039 14.1 0.0 0.093 12.9 0.0 1.6 1 0 0 1 1 1 0 Small spore protein J (Spore_SspJ) ADH_N PF08240.7 EXF76448.1 - 5e-28 97.0 0.4 8.2e-28 96.3 0.3 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF76448.1 - 2e-27 95.2 0.2 3.1e-27 94.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_3 PF01494.14 EXF76448.1 - 0.00012 21.2 0.0 0.00015 20.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain ADH_N_assoc PF13823.1 EXF76448.1 - 0.00035 20.1 0.0 0.00081 18.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated Shikimate_DH PF01488.15 EXF76448.1 - 0.015 15.3 0.1 0.024 14.7 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EXF76448.1 - 0.026 13.5 0.2 0.029 13.3 0.2 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase AIRS PF00586.19 EXF76448.1 - 0.043 14.0 0.2 0.097 12.9 0.1 1.6 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain Pyr_redox_3 PF13738.1 EXF76448.1 - 0.1 12.6 0.2 0.16 11.9 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase T2SM PF04612.7 EXF76449.1 - 0.22 11.3 1.3 0.29 10.8 0.9 1.1 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Peptidase_S8 PF00082.17 EXF76450.1 - 7.2e-40 136.9 1.7 1e-39 136.3 1.2 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EXF76450.1 - 2e-08 34.6 0.0 4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 Zn_clus PF00172.13 EXF76451.1 - 3.1e-09 36.5 12.8 5.6e-09 35.7 8.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF76451.1 - 1e-06 27.6 0.1 2.1e-06 26.5 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAP PF00956.13 EXF76452.1 - 5.2e-47 160.0 0.3 5.2e-47 160.0 0.2 1.7 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) LAT PF15234.1 EXF76452.1 - 0.12 11.7 0.2 0.12 11.7 0.1 2.1 1 1 1 2 2 2 0 Linker for activation of T-cells PBP1_TM PF14812.1 EXF76452.1 - 8.7 6.7 11.0 2.9 8.2 3.3 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 EXF76452.1 - 9.8 5.7 15.8 1.4 8.4 2.9 2.5 3 0 0 3 3 3 0 Sigma-70, non-essential region Kelch_5 PF13854.1 EXF76453.1 - 1.4e-09 37.7 13.4 1.6e-09 37.4 0.1 4.2 5 0 0 5 5 5 1 Kelch motif Kelch_6 PF13964.1 EXF76453.1 - 0.00094 19.2 9.9 0.66 10.2 0.0 4.7 5 0 0 5 5 5 2 Kelch motif Herpes_gE PF02480.11 EXF76453.1 - 0.0025 16.1 0.0 0.0035 15.6 0.0 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Gly-zipper_Omp PF13488.1 EXF76453.1 - 0.0071 15.9 1.1 0.0071 15.9 0.7 2.0 2 0 0 2 2 2 1 Glycine zipper Kelch_4 PF13418.1 EXF76453.1 - 0.0089 15.7 13.0 2.6 7.9 0.3 4.9 4 1 0 4 4 4 2 Galactose oxidase, central domain Gly-zipper_YMGG PF13441.1 EXF76453.1 - 0.022 14.2 2.0 0.073 12.6 1.4 1.9 1 0 0 1 1 1 0 YMGG-like Gly-zipper EphA2_TM PF14575.1 EXF76453.1 - 0.065 13.6 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Polysacc_synt_C PF14667.1 EXF76453.1 - 0.081 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis C-terminal domain Kelch_2 PF07646.10 EXF76453.1 - 0.52 10.1 7.0 14 5.6 0.0 4.6 4 1 0 4 4 4 0 Kelch motif Kelch_1 PF01344.20 EXF76453.1 - 0.95 9.0 5.2 3.2 7.3 0.0 3.6 3 1 0 3 3 3 0 Kelch motif Kelch_3 PF13415.1 EXF76453.1 - 1.2 9.4 8.3 1.6 9.0 0.0 4.1 4 0 0 4 4 4 0 Galactose oxidase, central domain DUF4243 PF14027.1 EXF76454.1 - 1.4e-90 304.0 0.2 1.9e-90 303.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) DUF479 PF04336.7 EXF76454.1 - 0.014 15.4 0.4 0.045 13.8 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF479 WD40 PF00400.27 EXF76455.1 - 1.6e-48 160.8 30.6 5e-11 42.0 0.0 11.8 13 0 0 13 13 13 8 WD domain, G-beta repeat Utp12 PF04003.7 EXF76455.1 - 1.8e-27 95.3 0.0 3e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Dip2/Utp12 Family eIF2A PF08662.6 EXF76455.1 - 2.4e-05 24.1 5.6 0.06 13.0 0.1 6.1 7 1 1 8 8 8 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EXF76455.1 - 0.00024 19.4 1.2 0.89 7.6 0.0 3.4 1 1 1 3 3 3 3 Nucleoporin Nup120/160 Nbas_N PF15492.1 EXF76455.1 - 0.0016 17.6 0.3 2.4 7.1 0.0 3.6 3 1 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal Septin PF00735.13 EXF76456.1 - 1.4e-115 385.2 0.2 2.2e-115 384.5 0.1 1.3 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EXF76456.1 - 8e-07 29.0 0.0 1.4e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EXF76456.1 - 3.3e-06 26.6 0.3 5.7e-05 22.6 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EXF76456.1 - 1e-05 24.7 0.0 2.9e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EXF76456.1 - 0.0024 18.3 0.1 0.0081 16.6 0.1 1.9 1 0 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 EXF76456.1 - 0.0034 17.0 0.1 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EXF76456.1 - 0.0039 17.3 0.4 0.017 15.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain AIG1 PF04548.11 EXF76456.1 - 0.0059 15.7 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 AIG1 family IIGP PF05049.8 EXF76456.1 - 0.0067 15.2 0.0 0.013 14.3 0.0 1.5 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.13 EXF76456.1 - 0.0094 15.4 1.0 0.015 14.8 0.0 1.8 2 0 0 2 2 2 1 FtsK/SpoIIIE family Pox_A32 PF04665.7 EXF76456.1 - 0.012 14.8 0.1 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein Ras PF00071.17 EXF76456.1 - 0.018 14.4 0.5 0.054 12.8 0.4 1.8 1 1 0 1 1 1 0 Ras family ArgK PF03308.11 EXF76456.1 - 0.035 12.8 2.0 0.92 8.2 0.0 3.0 3 0 0 3 3 3 0 ArgK protein T2SE PF00437.15 EXF76456.1 - 0.036 12.9 0.5 0.11 11.3 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein NACHT PF05729.7 EXF76456.1 - 0.04 13.5 0.0 0.077 12.6 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EXF76456.1 - 0.044 14.0 0.3 0.17 12.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter PduV-EutP PF10662.4 EXF76456.1 - 0.064 12.7 0.3 2.7 7.4 0.2 2.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.21 EXF76456.1 - 0.072 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_16 PF13191.1 EXF76456.1 - 0.096 12.6 2.2 0.35 10.8 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain DUF2968 PF11180.3 EXF76456.1 - 0.098 12.0 7.4 0.26 10.6 5.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) KAP_NTPase PF07693.9 EXF76456.1 - 0.1 11.5 1.8 0.19 10.7 1.2 1.7 1 1 0 1 1 1 0 KAP family P-loop domain Dynamin_N PF00350.18 EXF76456.1 - 0.12 12.2 8.2 0.68 9.7 0.1 3.1 2 1 1 3 3 3 0 Dynamin family RNA_helicase PF00910.17 EXF76456.1 - 0.12 12.5 0.0 0.36 11.0 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Ribosomal_L6e PF01159.14 EXF76456.1 - 0.22 11.7 5.5 3.8 7.7 0.1 3.3 3 0 0 3 3 3 0 Ribosomal protein L6e Atg14 PF10186.4 EXF76456.1 - 0.95 8.3 7.8 2.1 7.2 5.4 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Myc-LZ PF02344.10 EXF76456.1 - 4.5 6.9 11.6 1.5 8.5 3.2 2.9 2 1 0 2 2 2 0 Myc leucine zipper domain AAA_23 PF13476.1 EXF76456.1 - 9.5 6.4 21.1 2.7e+02 1.7 14.6 2.2 1 1 0 1 1 1 0 AAA domain BCDHK_Adom3 PF10436.4 EXF76457.1 - 1e-46 158.4 0.2 2e-46 157.5 0.1 1.4 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EXF76457.1 - 6.8e-11 41.8 0.1 4.5e-09 36.0 0.0 3.1 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EXF76457.1 - 0.00012 21.6 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EXF76457.1 - 0.1 12.3 0.1 1 9.1 0.0 2.3 2 1 0 2 2 2 0 Histidine kinase-like ATPase domain USP7_ICP0_bdg PF12436.3 EXF76458.1 - 9.9e-87 290.2 0.1 2.7e-85 285.5 0.0 2.4 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EXF76458.1 - 1e-77 260.3 11.7 1.3e-74 250.1 2.7 4.6 5 1 1 6 6 6 2 Ubiquitin-specific protease C-terminal UCH PF00443.24 EXF76458.1 - 2.1e-55 187.7 3.7 3.2e-55 187.1 2.5 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EXF76458.1 - 4.1e-27 95.3 0.4 8.4e-27 94.3 0.1 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EXF76458.1 - 5.3e-11 42.8 0.7 1.8e-10 41.1 0.1 2.2 2 0 0 2 2 2 1 MATH domain YukD PF08817.5 EXF76458.1 - 0.15 12.6 0.0 2 9.0 0.0 2.8 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD Tim17 PF02466.14 EXF76459.1 - 1.6e-48 163.9 9.3 2e-48 163.6 6.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_Omp PF13488.1 EXF76459.1 - 0.02 14.5 2.4 0.02 14.5 1.7 2.4 3 0 0 3 3 3 0 Glycine zipper DUF543 PF04418.7 EXF76459.1 - 0.033 14.1 0.2 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF543) SDH_alpha PF03313.10 EXF76459.1 - 0.044 12.8 0.9 0.07 12.1 0.7 1.3 1 0 0 1 1 1 0 Serine dehydratase alpha chain Glyco_hydro_16 PF00722.16 EXF76460.1 - 1.1e-08 34.6 0.9 2.2e-08 33.6 0.2 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 GP41 PF00517.12 EXF76460.1 - 0.069 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Retroviral envelope protein zf-HIT PF04438.11 EXF76460.1 - 0.21 11.2 0.3 0.4 10.3 0.2 1.4 1 0 0 1 1 1 0 HIT zinc finger SKIP_SNW PF02731.10 EXF76461.1 - 1.6e-67 225.8 5.3 1.6e-67 225.8 3.6 2.7 3 0 0 3 3 3 1 SKIP/SNW domain DUF4603 PF15376.1 EXF76461.1 - 0.96 6.5 16.7 1.3 6.1 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Nucleo_P87 PF07267.6 EXF76461.1 - 1.9 7.0 8.7 3.6 6.1 6.0 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 FAM60A PF15396.1 EXF76461.1 - 2.4 7.8 8.6 6.4 6.4 6.0 1.8 1 0 0 1 1 1 0 Protein Family FAM60A BTV_NS2 PF04514.7 EXF76461.1 - 8.9 5.0 14.8 17 4.1 10.3 1.5 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 HET PF06985.6 EXF76462.1 - 2e-14 53.9 1.8 4.3e-13 49.6 1.2 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FAD_binding_4 PF01565.18 EXF76463.1 - 2.2e-21 75.8 1.3 5e-21 74.6 0.9 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF76463.1 - 7.6e-06 25.7 0.2 1.6e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Ost4 PF10215.4 EXF76464.1 - 0.12 11.8 1.9 0.34 10.4 1.3 1.8 1 0 0 1 1 1 0 Oligosaccaryltransferase RmlD_sub_bind PF04321.12 EXF76465.1 - 2.3e-54 184.2 0.0 2.7e-54 183.9 0.0 1.0 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EXF76465.1 - 2.4e-22 79.5 0.0 3.1e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EXF76465.1 - 2.4e-13 49.5 0.0 2.5e-11 42.9 0.0 2.2 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EXF76465.1 - 4.6e-08 32.0 0.0 1.6e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EXF76465.1 - 2.2e-06 26.8 0.3 0.00036 19.5 0.0 2.8 1 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EXF76465.1 - 2.7e-05 24.2 0.1 3.5e-05 23.8 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EXF76465.1 - 0.00096 19.1 1.3 0.035 14.0 0.9 2.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF76465.1 - 0.078 12.6 0.2 12 5.4 0.0 2.4 2 0 0 2 2 2 0 KR domain polyprenyl_synt PF00348.12 EXF76467.1 - 8.2e-70 234.6 0.0 1.1e-69 234.2 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase APC8 PF04049.8 EXF76468.1 - 1.9e-39 134.6 1.8 4.4e-39 133.4 0.1 2.2 2 0 0 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 EXF76468.1 - 4.3e-23 79.9 1.4 0.00029 20.2 0.0 7.7 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 EXF76468.1 - 2e-21 75.4 5.7 1.2e-06 28.0 0.0 6.5 4 1 2 6 6 6 6 TPR repeat TPR_8 PF13181.1 EXF76468.1 - 1e-17 62.4 7.7 0.00025 20.5 0.0 7.1 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EXF76468.1 - 6.9e-17 59.9 15.5 0.071 13.0 0.0 8.8 9 0 0 9 9 8 6 Tetratricopeptide repeat TPR_16 PF13432.1 EXF76468.1 - 1.9e-12 47.4 3.4 3.4e-05 24.3 0.0 6.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 EXF76468.1 - 9.3e-12 44.4 6.7 0.024 15.2 0.0 8.1 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 EXF76468.1 - 1.4e-11 44.1 10.5 0.00019 21.2 0.3 6.1 4 1 2 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 EXF76468.1 - 2.3e-06 27.6 3.0 0.31 11.1 0.0 4.9 4 1 1 5 5 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EXF76468.1 - 7.3e-06 26.1 13.1 6.4 7.4 0.2 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EXF76468.1 - 3.5e-05 23.2 7.4 0.35 10.7 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.1 EXF76468.1 - 0.00054 19.9 0.1 2.4 8.5 0.0 5.0 4 0 0 4 4 3 1 Tetratricopeptide repeat DUF3856 PF12968.2 EXF76468.1 - 0.00077 19.3 0.8 0.053 13.3 0.1 3.3 1 1 0 2 2 2 1 Domain of Unknown Function (DUF3856) TPR_9 PF13371.1 EXF76468.1 - 0.0025 17.6 10.0 1.5 8.6 0.2 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EXF76468.1 - 0.0026 18.0 9.1 2.7 8.4 0.1 6.0 7 1 0 7 7 6 1 Tetratricopeptide repeat DUF4398 PF14346.1 EXF76468.1 - 0.054 13.5 0.1 0.19 11.8 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) DUF2424 PF10340.4 EXF76468.1 - 0.12 10.9 0.0 0.19 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) G-alpha PF00503.15 EXF76471.1 - 1.5e-126 422.2 0.9 1.7e-126 422.0 0.6 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EXF76471.1 - 1.5e-15 56.8 0.4 4.1e-10 39.1 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 EXF76471.1 - 0.0012 19.3 0.0 0.98 9.9 0.0 2.8 3 0 0 3 3 3 2 Miro-like protein Gtr1_RagA PF04670.7 EXF76471.1 - 0.0038 16.4 4.8 0.18 10.9 0.1 2.6 1 1 1 2 2 2 2 Gtr1/RagA G protein conserved region AAA_29 PF13555.1 EXF76471.1 - 0.05 13.1 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain GST_C PF00043.20 EXF76472.1 - 1.4e-11 44.2 0.0 2.3e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EXF76472.1 - 9.9e-08 31.7 0.7 2e-07 30.8 0.1 1.9 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EXF76472.1 - 2.2e-07 30.9 0.0 4.8e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EXF76472.1 - 1e-06 28.8 0.0 1.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EXF76472.1 - 2.8e-05 24.5 0.2 4.9e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EXF76472.1 - 3e-05 23.9 0.0 7.2e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain MetRS-N PF09635.5 EXF76472.1 - 0.11 12.8 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 MetRS-N binding domain DUF2693 PF10902.3 EXF76473.1 - 0.37 10.7 3.4 0.78 9.6 2.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2693) FAM176 PF14851.1 EXF76473.1 - 0.73 9.5 6.2 0.52 9.9 0.4 2.1 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.1 EXF76473.1 - 1.7 9.0 12.6 0.43 10.9 1.9 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TLP-20 PF06088.6 EXF76473.1 - 3.2 7.3 8.4 0.42 10.2 1.6 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Lon_C PF05362.8 EXF76474.1 - 8.1e-64 214.6 0.0 1.4e-63 213.9 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EXF76474.1 - 2.2e-37 128.7 0.7 3.6e-36 124.7 0.5 2.5 1 1 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EXF76474.1 - 5.5e-22 78.3 0.0 1.7e-21 76.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EXF76474.1 - 4.8e-07 29.8 0.0 2.2e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ChlI PF13541.1 EXF76474.1 - 6.4e-07 28.9 0.0 1.6e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 EXF76474.1 - 1.1e-06 28.3 0.0 2.9e-06 27.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EXF76474.1 - 8.9e-06 25.8 0.1 0.00021 21.4 0.0 2.8 2 1 0 2 2 1 1 AAA domain AAA_17 PF13207.1 EXF76474.1 - 9.2e-06 26.4 0.3 4.5e-05 24.2 0.0 2.4 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EXF76474.1 - 8.4e-05 22.6 2.9 0.0028 17.6 0.0 3.3 3 1 0 3 3 3 1 AAA ATPase domain AAA_PrkA PF08298.6 EXF76474.1 - 0.00017 20.4 0.0 0.00032 19.5 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.7 EXF76474.1 - 0.00035 19.6 0.0 0.002 17.1 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EXF76474.1 - 0.0024 17.7 0.0 0.01 15.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EXF76474.1 - 0.0046 17.2 0.0 0.0046 17.2 0.0 3.0 4 0 0 4 4 2 1 AAA domain MobB PF03205.9 EXF76474.1 - 0.014 15.0 0.0 0.04 13.6 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EXF76474.1 - 0.02 14.3 1.1 0.073 12.4 0.0 2.4 3 0 0 3 3 3 0 IstB-like ATP binding protein TIP49 PF06068.8 EXF76474.1 - 0.022 13.4 0.1 0.51 8.9 0.0 2.3 2 0 0 2 2 2 0 TIP49 C-terminus ATP-synt_ab PF00006.20 EXF76474.1 - 0.022 14.2 0.1 0.14 11.6 0.0 2.1 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RNA_helicase PF00910.17 EXF76474.1 - 0.025 14.7 0.0 0.085 13.0 0.0 2.0 1 0 0 1 1 1 0 RNA helicase MMR_HSR1 PF01926.18 EXF76474.1 - 0.028 14.3 0.2 3.4 7.6 0.0 2.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF258 PF03193.11 EXF76474.1 - 0.036 13.2 0.9 0.076 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_28 PF13521.1 EXF76474.1 - 0.038 13.9 0.2 2.3 8.1 0.0 3.1 3 0 0 3 3 2 0 AAA domain NTPase_1 PF03266.10 EXF76474.1 - 0.04 13.6 0.2 0.78 9.4 0.0 2.5 1 1 1 2 2 2 0 NTPase AAA_25 PF13481.1 EXF76474.1 - 0.059 12.7 0.0 0.16 11.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EXF76474.1 - 0.081 12.8 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EXF76474.1 - 0.17 11.8 0.2 1.6 8.6 0.0 2.4 1 1 1 2 2 2 0 AAA domain ClpB_D2-small PF10431.4 EXF76474.1 - 0.18 11.7 5.3 0.076 12.9 0.3 2.5 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein ABC_tran PF00005.22 EXF76474.1 - 0.66 10.2 4.8 0.6 10.4 0.0 2.9 3 0 0 3 3 3 0 ABC transporter Pkinase PF00069.20 EXF76475.1 - 7.7e-12 44.9 0.0 9.3e-11 41.3 0.0 2.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF76475.1 - 5.2e-10 38.8 0.0 4.6e-09 35.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Catalase PF00199.14 EXF76476.1 - 2.4e-182 605.8 2.7 3e-182 605.5 1.9 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EXF76476.1 - 5.6e-10 38.9 0.0 1.2e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive Arf PF00025.16 EXF76477.1 - 5.8e-73 243.8 0.0 7.9e-73 243.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EXF76477.1 - 5.6e-13 48.4 0.0 7.9e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EXF76477.1 - 3.6e-11 42.3 0.5 2.1e-07 30.0 0.0 2.5 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EXF76477.1 - 1.6e-10 40.6 0.0 2.3e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EXF76477.1 - 3.3e-08 34.0 0.1 8e-08 32.8 0.0 1.7 2 0 0 2 2 1 1 Miro-like protein Gtr1_RagA PF04670.7 EXF76477.1 - 3.6e-08 32.8 0.0 5.1e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EXF76477.1 - 9.6e-06 25.5 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EXF76477.1 - 0.00013 21.4 0.1 0.013 14.9 0.0 2.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AF1Q PF15017.1 EXF76477.1 - 0.0013 18.5 0.5 0.0029 17.4 0.4 1.5 1 0 0 1 1 1 1 Drug resistance and apoptosis regulator Ribosomal_60s PF00428.14 EXF76477.1 - 0.0021 18.4 1.5 0.0049 17.2 1.0 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein FeoB_N PF02421.13 EXF76477.1 - 0.048 12.9 0.6 0.23 10.7 0.4 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B PI3K_1B_p101 PF10486.4 EXF76477.1 - 0.13 9.8 0.3 0.17 9.4 0.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Myc_N PF01056.13 EXF76477.1 - 0.26 10.4 1.5 0.39 9.8 1.1 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Ribosomal_L39 PF00832.15 EXF76478.1 - 1.3e-22 79.0 9.0 1.4e-22 78.8 6.3 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein Selenoprotein_S PF06936.6 EXF76478.1 - 0.11 11.9 0.7 0.13 11.7 0.5 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) Skp1 PF01466.14 EXF76479.1 - 1.2e-39 134.1 1.1 2.6e-39 133.0 0.8 1.6 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EXF76479.1 - 8.2e-20 70.6 0.1 1.9e-19 69.5 0.0 1.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain DUF4375 PF14300.1 EXF76479.1 - 0.0069 16.3 0.9 0.01 15.8 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4375) DUF22 PF01629.11 EXF76480.1 - 0.0075 15.7 0.7 0.016 14.6 0.5 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF22 Pkinase PF00069.20 EXF76481.1 - 2.5e-68 230.0 0.0 4.7e-68 229.1 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF76481.1 - 5.8e-50 169.7 0.0 9.8e-50 169.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ras_bdg_2 PF14847.1 EXF76481.1 - 3.3e-29 100.9 0.0 6.1e-29 100.0 0.0 1.5 1 0 0 1 1 1 1 Ras-binding domain of Byr2 RA PF00788.18 EXF76481.1 - 3.7e-13 49.7 0.0 6.3e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Kinase-like PF14531.1 EXF76481.1 - 2.2e-07 30.1 0.0 0.0001 21.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EXF76481.1 - 0.036 13.1 0.0 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Abhydrolase_6 PF12697.2 EXF76482.1 - 1.3e-25 90.6 0.3 1.7e-25 90.2 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF76482.1 - 6.8e-09 35.6 0.4 1.1e-08 34.9 0.3 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF76482.1 - 1.7e-05 24.5 0.0 0.026 14.0 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold AA_kinase PF00696.23 EXF76482.1 - 0.046 13.2 0.1 0.12 11.8 0.1 1.4 1 1 0 1 1 1 0 Amino acid kinase family DUF900 PF05990.7 EXF76482.1 - 0.073 12.3 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) UPF0182 PF03699.8 EXF76483.1 - 0.42 8.4 5.4 0.75 7.6 3.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) SnoaL PF07366.7 EXF76484.1 - 3.5e-06 26.6 0.0 7.5e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EXF76484.1 - 0.0012 19.2 0.1 0.0025 18.1 0.1 1.5 1 0 0 1 1 1 1 SnoaL-like domain DLH PF01738.13 EXF76484.1 - 0.0027 17.0 0.0 0.0055 16.0 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family RgpF PF05045.7 EXF76485.1 - 0.0024 16.5 0.1 0.14 10.6 0.0 2.1 2 0 0 2 2 2 2 Rhamnan synthesis protein F Macoilin PF09726.4 EXF76485.1 - 1.1 7.4 13.9 1.4 7.1 9.7 1.1 1 0 0 1 1 1 0 Transmembrane protein zf-C2H2 PF00096.21 EXF76489.1 - 0.012 15.8 3.6 0.019 15.3 0.1 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF76489.1 - 0.25 11.7 0.3 0.25 11.7 0.2 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger DUF1640 PF07798.6 EXF76490.1 - 7.3e-14 52.1 2.6 1.3e-13 51.3 1.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) DUF1191 PF06697.7 EXF76490.1 - 0.039 12.7 0.1 0.064 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) PUF PF00806.14 EXF76491.1 - 8.9e-63 204.4 14.7 2.6e-08 32.9 0.1 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat SapB_2 PF03489.12 EXF76491.1 - 0.11 12.5 0.8 8.5 6.5 0.0 3.2 2 0 0 2 2 2 0 Saposin-like type B, region 2 TMEM154 PF15102.1 EXF76492.1 - 0.049 13.3 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family RCR PF12273.3 EXF76492.1 - 0.34 11.4 3.1 0.68 10.4 2.2 1.6 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Sulfatase PF00884.18 EXF76493.1 - 2.3e-45 155.1 0.0 3.1e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EXF76493.1 - 0.0006 19.2 0.1 0.12 11.6 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EXF76493.1 - 0.024 13.0 0.0 0.031 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) SET PF00856.23 EXF76494.1 - 5.3e-10 39.8 0.0 1.4e-09 38.4 0.0 1.7 1 1 0 1 1 1 1 SET domain F-box-like PF12937.2 EXF76495.1 - 0.09 12.5 0.9 0.26 11.0 0.1 2.2 2 0 0 2 2 2 0 F-box-like Kinetochor_Ybp2 PF08568.5 EXF76496.1 - 1.1e-96 324.6 0.0 1.3e-96 324.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family, YAP/Alf4/glomulin Pex24p PF06398.6 EXF76496.1 - 4.9e-05 22.2 0.0 8.9e-05 21.4 0.0 1.4 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin FANCI_S3 PF14677.1 EXF76496.1 - 0.018 14.4 0.0 0.098 12.0 0.0 2.1 1 1 1 2 2 2 0 FANCI solenoid 3 DUF3704 PF12488.3 EXF76496.1 - 0.069 12.7 0.7 0.18 11.4 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3704) Glyco_transf_28 PF03033.15 EXF76497.1 - 6.8e-17 61.5 0.0 2e-16 60.0 0.0 1.9 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EXF76497.1 - 1.6e-06 27.0 0.0 4.3e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase ATG_C PF09333.6 EXF76497.1 - 0.0052 16.8 0.0 0.034 14.3 0.0 2.3 2 0 0 2 2 2 1 ATG C terminal domain Glyco_tran_28_C PF04101.11 EXF76497.1 - 0.014 15.0 1.6 0.018 14.6 0.0 2.0 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain Imm15 PF15590.1 EXF76499.1 - 0.019 14.0 0.2 0.39 9.8 0.1 2.5 1 1 1 2 2 2 0 Immunity protein 15 Methyltransf_13 PF08421.6 EXF76500.1 - 0.19 11.2 0.7 4.5 6.8 0.0 2.6 2 1 0 2 2 2 0 Putative zinc binding domain zf-C2H2_4 PF13894.1 EXF76502.1 - 0.022 15.0 1.0 0.022 15.0 0.7 2.5 2 1 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF76502.1 - 0.061 13.6 1.9 0.061 13.6 1.3 2.7 2 1 1 3 3 3 0 Zinc finger, C2H2 type zf-H2C2_5 PF13909.1 EXF76503.1 - 0.045 13.9 1.3 0.045 13.9 0.9 3.0 3 1 1 4 4 4 0 C2H2-type zinc-finger domain Folliculin PF11704.3 EXF76504.1 - 1.3e-27 96.4 0.0 5.4e-27 94.4 0.0 2.1 2 1 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport Actino_peptide PF14408.1 EXF76504.1 - 0.64 9.9 6.3 0.2 11.6 1.4 2.4 3 0 0 3 3 3 0 Ribosomally synthesized peptide in actinomycetes AAA PF00004.24 EXF76505.1 - 1.8e-45 154.3 0.6 6.1e-45 152.6 0.0 2.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EXF76505.1 - 8.8e-09 35.2 0.6 2.9e-08 33.5 0.1 2.2 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EXF76505.1 - 4.8e-08 33.1 0.0 1e-07 32.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EXF76505.1 - 4.9e-07 29.9 0.0 1.6e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EXF76505.1 - 1.9e-06 28.0 1.8 0.001 19.1 0.0 2.8 2 1 1 3 3 2 2 AAA domain DUF815 PF05673.8 EXF76505.1 - 2.9e-06 26.3 0.0 6.3e-06 25.2 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EXF76505.1 - 0.00021 21.1 0.0 0.00083 19.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EXF76505.1 - 0.00036 19.6 0.0 0.00085 18.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EXF76505.1 - 0.00039 20.4 0.0 0.00081 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EXF76505.1 - 0.00049 19.8 0.8 0.06 13.0 0.0 3.3 3 1 0 4 4 4 1 NACHT domain AAA_17 PF13207.1 EXF76505.1 - 0.00055 20.7 0.1 0.0023 18.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.8 EXF76505.1 - 0.0011 17.7 0.0 0.0021 16.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Zeta_toxin PF06414.7 EXF76505.1 - 0.0013 17.8 0.1 0.0038 16.3 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 EXF76505.1 - 0.0013 18.3 0.2 0.0035 17.0 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 EXF76505.1 - 0.0018 18.4 0.0 0.0038 17.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NTPase_1 PF03266.10 EXF76505.1 - 0.0027 17.4 0.0 0.0089 15.7 0.0 1.9 2 0 0 2 2 1 1 NTPase AAA_23 PF13476.1 EXF76505.1 - 0.0034 17.7 0.6 0.85 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EXF76505.1 - 0.0037 16.8 0.0 0.011 15.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EXF76505.1 - 0.0052 16.6 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EXF76505.1 - 0.0053 16.3 0.9 0.016 14.7 0.0 2.1 2 1 1 3 3 3 1 AAA domain UPF0079 PF02367.12 EXF76505.1 - 0.0054 16.3 0.0 0.041 13.5 0.0 2.1 1 1 1 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EXF76505.1 - 0.0054 16.3 0.2 0.021 14.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EXF76505.1 - 0.006 15.7 0.2 0.013 14.6 0.1 1.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EXF76505.1 - 0.0085 16.3 0.0 0.026 14.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EXF76505.1 - 0.0088 15.7 0.8 0.058 13.0 0.0 2.5 2 1 0 2 2 2 1 Archaeal ATPase IstB_IS21 PF01695.12 EXF76505.1 - 0.01 15.2 0.5 0.024 14.0 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein Viral_Hsp90 PF03225.9 EXF76505.1 - 0.011 14.1 0.0 0.016 13.5 0.0 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue AAA_24 PF13479.1 EXF76505.1 - 0.011 15.3 0.5 0.03 13.9 0.1 1.8 2 0 0 2 2 2 0 AAA domain Bac_DnaA PF00308.13 EXF76505.1 - 0.015 14.9 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_25 PF13481.1 EXF76505.1 - 0.016 14.5 2.5 0.079 12.3 0.1 2.6 2 1 1 3 3 2 0 AAA domain KaiC PF06745.8 EXF76505.1 - 0.024 13.7 1.1 0.45 9.5 0.0 2.6 3 0 0 3 3 3 0 KaiC Sigma54_activat PF00158.21 EXF76505.1 - 0.04 13.3 0.1 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EXF76505.1 - 0.041 13.9 0.1 0.37 10.8 0.0 2.5 2 1 0 2 2 2 0 Sigma-54 interaction domain AFG1_ATPase PF03969.11 EXF76505.1 - 0.049 12.4 0.0 0.13 11.0 0.0 1.7 2 0 0 2 2 2 0 AFG1-like ATPase Cast PF10174.4 EXF76505.1 - 0.065 11.2 2.2 0.11 10.4 0.9 1.7 2 0 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone NB-ARC PF00931.17 EXF76505.1 - 0.11 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 EXF76505.1 - 0.17 10.7 0.0 0.31 9.8 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 CENP-U PF13097.1 EXF76506.1 - 0.013 15.4 1.5 0.015 15.1 1.0 1.1 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit DUF822 PF05687.8 EXF76506.1 - 0.66 10.3 4.1 0.86 9.9 2.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Mis14 PF08641.7 EXF76507.1 - 1.5e-09 38.0 0.1 2.5e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 Kinetochore protein Mis14 like Snf7 PF03357.16 EXF76507.1 - 0.00019 20.8 0.7 0.0089 15.4 0.1 2.1 2 0 0 2 2 2 1 Snf7 CRISPR_Cse1 PF09481.5 EXF76507.1 - 0.0079 14.9 1.0 0.0095 14.7 0.7 1.1 1 0 0 1 1 1 1 CRISPR-associated protein Cse1 (CRISPR_cse1) Filament PF00038.16 EXF76507.1 - 0.027 13.9 2.5 0.049 13.1 0.3 1.9 2 0 0 2 2 2 0 Intermediate filament protein DUF1110 PF06533.7 EXF76507.1 - 0.082 12.7 4.5 0.049 13.4 1.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1110) UPF0075 PF03702.9 EXF76507.1 - 0.11 11.3 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0075) DUF3138 PF11336.3 EXF76507.1 - 0.16 10.0 0.5 0.22 9.6 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) CRAL_TRIO PF00650.15 EXF76508.1 - 9.9e-36 122.6 0.0 1.5e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EXF76508.1 - 2.7e-10 40.2 2.5 3e-10 40.0 0.4 2.1 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EXF76508.1 - 0.0017 18.2 0.1 0.016 15.1 0.0 2.2 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain Prefoldin PF02996.12 EXF76509.1 - 6.3e-34 116.1 0.0 1.1e-33 115.4 0.0 1.4 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin_2 PF01920.15 EXF76509.1 - 0.0011 18.6 5.1 0.0028 17.3 0.0 3.0 3 1 1 4 4 4 1 Prefoldin subunit End3 PF12761.2 EXF76509.1 - 0.024 14.2 0.8 0.53 9.8 0.0 2.4 1 1 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 HR1 PF02185.11 EXF76509.1 - 0.028 14.1 0.1 0.086 12.5 0.0 1.8 2 0 0 2 2 2 0 Hr1 repeat Filament PF00038.16 EXF76509.1 - 0.035 13.5 2.7 0.77 9.1 0.1 2.1 2 0 0 2 2 2 0 Intermediate filament protein FlaC_arch PF05377.6 EXF76509.1 - 0.063 13.1 1.3 1.8 8.5 0.1 2.9 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4201 PF13870.1 EXF76509.1 - 0.19 11.1 3.1 0.58 9.5 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) Mito_carr PF00153.22 EXF76510.1 - 2.4e-61 203.4 2.3 1.3e-21 76.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RINT1_TIP1 PF04437.8 EXF76511.1 - 3.7e-96 322.6 0.0 8.2e-96 321.4 0.0 1.6 2 0 0 2 2 2 1 RINT-1 / TIP-1 family DUF883 PF05957.8 EXF76511.1 - 0.052 13.9 5.5 7.9 6.9 0.8 3.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) DUF4164 PF13747.1 EXF76511.1 - 0.093 12.8 8.6 0.16 12.1 3.3 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Fig1 PF12351.3 EXF76512.1 - 3.9e-56 189.8 2.8 3.9e-56 189.8 2.0 2.0 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 SUR7 PF06687.7 EXF76512.1 - 3.4e-10 39.8 5.8 5.2e-10 39.2 4.0 1.3 1 1 0 1 1 1 1 SUR7/PalI family DUF898 PF05987.8 EXF76512.1 - 3.5e-05 22.8 6.2 3.5e-05 22.8 4.3 1.8 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) DUF202 PF02656.10 EXF76512.1 - 0.053 13.7 7.4 3.3 7.9 2.6 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF202) MLTD_N PF06474.7 EXF76512.1 - 0.2 11.8 2.6 0.75 10.0 1.8 2.1 1 0 0 1 1 1 0 MltD lipid attachment motif DUF2976 PF11190.3 EXF76512.1 - 0.77 9.3 0.0 0.77 9.3 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2976) Glyco_hydro_47 PF01532.15 EXF76513.1 - 2e-177 590.4 0.0 2.6e-177 590.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 p450 PF00067.17 EXF76515.1 - 1.2e-34 119.6 0.0 5.1e-34 117.5 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 RTA1 PF04479.8 EXF76516.1 - 2e-47 161.5 10.8 3e-47 160.9 7.5 1.2 1 0 0 1 1 1 1 RTA1 like protein DUF2919 PF11143.3 EXF76516.1 - 8.7 6.1 13.8 5 6.9 3.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) Zn_clus PF00172.13 EXF76517.1 - 1.3e-07 31.3 7.6 2.2e-07 30.6 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF76517.1 - 4.9e-05 22.0 0.0 7.7e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain YebG PF07130.7 EXF76517.1 - 0.11 12.2 0.2 0.23 11.1 0.2 1.5 1 0 0 1 1 1 0 YebG protein MFS_1 PF07690.11 EXF76518.1 - 3e-46 157.7 29.1 3.5e-46 157.5 20.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF76518.1 - 2.8e-17 62.4 8.0 1e-16 60.6 5.6 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EXF76518.1 - 0.00015 20.1 2.4 0.00022 19.5 1.6 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EXF76518.1 - 0.00047 18.4 2.2 0.00077 17.7 1.5 1.4 1 0 0 1 1 1 1 Transmembrane secretion effector FPN1 PF06963.7 EXF76518.1 - 0.0049 15.3 0.2 0.0098 14.3 0.0 1.6 2 0 0 2 2 2 1 Ferroportin1 (FPN1) NPP1 PF05630.6 EXF76519.1 - 9.9e-35 120.1 0.0 1.6e-34 119.5 0.0 1.3 1 1 0 1 1 1 1 Necrosis inducing protein (NPP1) Peptidase_S8 PF00082.17 EXF76521.1 - 3.6e-11 42.7 0.1 6.9e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.2 EXF76523.1 - 6e-68 225.2 0.0 2e-17 63.3 0.0 8.5 2 2 8 10 10 10 10 Ankyrin repeats (3 copies) Ank PF00023.25 EXF76523.1 - 2.4e-54 178.5 16.4 7.8e-08 31.7 0.1 15.1 14 1 0 14 14 14 11 Ankyrin repeat Ank_4 PF13637.1 EXF76523.1 - 6e-52 173.1 11.4 8.4e-07 29.3 0.1 13.9 9 3 7 16 16 16 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF76523.1 - 5.7e-45 146.8 2.7 0.00039 20.4 0.0 16.2 15 1 0 15 15 15 9 Ankyrin repeat Ank_5 PF13857.1 EXF76523.1 - 4.2e-37 125.3 8.1 2.5e-06 27.5 0.2 11.9 7 3 5 12 12 12 8 Ankyrin repeats (many copies) DUF1744 PF08490.7 EXF76524.1 - 3.8e-152 506.4 0.0 5.3e-152 506.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EXF76524.1 - 1.2e-63 214.9 0.3 2.2e-63 214.1 0.2 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EXF76524.1 - 1.9e-21 76.4 0.2 5.6e-21 74.8 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EXF76524.1 - 2.9e-09 36.7 0.2 7.5e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.1 EXF76524.1 - 1.7e-05 24.7 0.2 0.00017 21.4 0.0 2.6 2 0 0 2 2 2 1 RNase_H superfamily DUF3767 PF12597.3 EXF76525.1 - 1.2e-34 118.4 1.6 1.8e-34 117.9 0.0 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF3767) 5TM-5TMR_LYT PF07694.7 EXF76525.1 - 0.0021 17.3 0.1 0.0028 16.9 0.1 1.1 1 0 0 1 1 1 1 5TMR of 5TMR-LYT Aldose_epim PF01263.15 EXF76527.1 - 2.1e-55 187.9 0.0 2.6e-55 187.6 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase zf-met2 PF12907.2 EXF76527.1 - 0.024 14.6 0.4 0.049 13.6 0.3 1.5 1 0 0 1 1 1 0 Zinc-binding PBP1_TM PF14812.1 EXF76528.1 - 0.0065 16.7 7.1 0.0065 16.7 4.9 5.7 4 2 3 7 7 7 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_transf_20 PF00982.16 EXF76529.1 - 2.9e-198 659.1 0.0 3.4e-198 658.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyltransferase family 20 Glyco_transf_5 PF08323.6 EXF76529.1 - 0.028 13.8 0.1 0.096 12.1 0.0 1.9 2 0 0 2 2 2 0 Starch synthase catalytic domain VID27 PF08553.5 EXF76530.1 - 0 1129.1 0.2 0 1128.9 0.1 1.0 1 0 0 1 1 1 1 VID27 cytoplasmic protein BUD22 PF09073.5 EXF76530.1 - 0.078 12.0 10.8 0.18 10.8 7.5 1.5 1 0 0 1 1 1 0 BUD22 Rav1p_C PF12234.3 EXF76530.1 - 0.16 10.0 0.0 0.16 10.0 0.0 1.6 2 0 0 2 2 2 0 RAVE protein 1 C terminal Anoctamin PF04547.7 EXF76530.1 - 1.5 7.3 2.8 2.4 6.7 2.0 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel CDC45 PF02724.9 EXF76530.1 - 4.2 5.2 12.5 6.5 4.6 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Prenylcys_lyase PF07156.9 EXF76531.1 - 5.7e-36 124.1 0.0 1.2e-24 86.9 0.0 2.2 2 0 0 2 2 2 2 Prenylcysteine lyase NAD_binding_8 PF13450.1 EXF76531.1 - 1.7e-11 43.9 0.1 5.1e-11 42.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EXF76531.1 - 1.6e-06 27.4 0.0 9.3e-06 24.9 0.0 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EXF76531.1 - 1.1e-05 24.5 0.1 8.3e-05 21.6 0.1 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF76531.1 - 7.8e-05 22.6 0.3 0.14 11.9 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF76531.1 - 0.00026 20.7 0.1 0.0047 16.7 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EXF76531.1 - 0.026 14.6 0.1 0.68 9.9 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF76531.1 - 0.052 12.6 0.1 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Herpes_UL4 PF03277.8 EXF76531.1 - 0.14 11.3 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL4 family Cpn60_TCP1 PF00118.19 EXF76532.1 - 3.2e-148 494.3 1.1 3.6e-148 494.1 0.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PDCD2_C PF04194.8 EXF76533.1 - 2.8e-51 173.3 0.1 1.1e-50 171.3 0.0 2.0 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain Ribosomal_60s PF00428.14 EXF76533.1 - 0.0026 18.1 12.8 0.016 15.6 1.3 2.5 2 0 0 2 2 2 2 60s Acidic ribosomal protein Pol_alpha_B_N PF08418.5 EXF76533.1 - 1.4 8.4 9.2 2.1 7.8 6.4 1.2 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal PCI_Csn8 PF10075.4 EXF76534.1 - 5.2e-36 123.5 0.0 7.8e-36 122.9 0.0 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EXF76534.1 - 1.5e-23 83.3 0.1 2e-23 83.0 0.1 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF3453 PF11935.3 EXF76534.1 - 0.065 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) DNA_ligase_A_M PF01068.16 EXF76535.1 - 3.8e-47 160.2 0.2 1.5e-44 151.7 0.0 2.3 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EXF76535.1 - 7.4e-40 136.6 0.0 1.2e-39 135.9 0.0 1.4 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EXF76535.1 - 3e-20 72.4 0.0 2.8e-19 69.3 0.0 2.6 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region Adaptin_N PF01602.15 EXF76536.1 - 1.6e-148 495.3 1.7 2.2e-148 494.8 1.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EXF76536.1 - 2.4e-25 89.4 0.1 1.1e-24 87.2 0.0 2.1 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EXF76536.1 - 3.4e-17 62.5 0.2 5.5e-07 29.7 0.0 5.2 3 2 2 5 5 5 3 HEAT repeats HEAT PF02985.17 EXF76536.1 - 1.3e-11 43.5 3.3 0.013 15.4 0.0 6.0 7 0 0 7 7 6 3 HEAT repeat HEAT_EZ PF13513.1 EXF76536.1 - 9.9e-06 25.8 0.8 2 9.0 0.0 5.8 5 1 1 6 6 6 1 HEAT-like repeat Atx10homo_assoc PF09759.4 EXF76536.1 - 0.0028 17.3 0.0 0.079 12.7 0.0 3.0 3 0 0 3 3 3 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 EXF76536.1 - 0.0033 17.1 0.7 3 7.8 0.0 4.8 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat UNC45-central PF11701.3 EXF76536.1 - 0.011 15.4 0.1 0.49 10.0 0.0 2.6 2 1 0 2 2 2 0 Myosin-binding striated muscle assembly central CLASP_N PF12348.3 EXF76536.1 - 0.037 13.3 0.2 1.5 8.1 0.0 3.2 3 1 1 4 4 4 0 CLASP N terminal DUF1548 PF07579.6 EXF76536.1 - 0.15 12.1 0.2 6.3 6.9 0.0 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1548) AF0941-like PF14591.1 EXF76536.1 - 0.67 10.0 3.2 2.2 8.3 1.2 2.5 3 0 0 3 3 3 0 AF0941-like BolA PF01722.13 EXF76537.1 - 2.2e-21 75.5 0.0 2.8e-21 75.2 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein NIF3 PF01784.13 EXF76538.1 - 4.5e-59 199.9 0.0 5.4e-59 199.6 0.0 1.0 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) ETF PF01012.16 EXF76538.1 - 0.032 13.9 0.5 0.31 10.7 0.2 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein domain Peripla_BP_6 PF13458.1 EXF76538.1 - 0.032 13.5 0.1 0.083 12.2 0.1 1.8 1 1 1 2 2 2 0 Periplasmic binding protein Phosphonate-bd PF12974.2 EXF76538.1 - 0.034 13.5 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Vps51 PF08700.6 EXF76539.1 - 3.3e-30 103.7 0.1 9.1e-30 102.3 0.0 1.7 2 0 0 2 2 2 1 Vps51/Vps67 Dor1 PF04124.7 EXF76539.1 - 0.00056 18.4 0.1 0.00077 18.0 0.1 1.1 1 0 0 1 1 1 1 Dor1-like family COG5 PF10392.4 EXF76539.1 - 0.001 19.0 0.0 0.0017 18.3 0.0 1.4 1 1 0 1 1 1 1 Golgi transport complex subunit 5 Sec5 PF15469.1 EXF76539.1 - 0.07 12.8 0.0 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 Exocyst complex component Sec5 DUF1767 PF08585.7 EXF76540.1 - 4.4e-06 26.8 0.4 2.1e-05 24.7 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1767) TPR_11 PF13414.1 EXF76541.1 - 2.8e-42 142.1 34.4 1.6e-06 27.6 0.1 12.8 12 2 1 13 13 13 10 TPR repeat TPR_16 PF13432.1 EXF76541.1 - 1e-36 124.7 36.0 2.1e-07 31.4 0.1 12.5 10 4 4 14 14 13 8 Tetratricopeptide repeat TPR_14 PF13428.1 EXF76541.1 - 5.4e-34 113.5 24.0 0.0013 19.1 0.0 15.9 12 5 6 18 18 16 7 Tetratricopeptide repeat TPR_2 PF07719.12 EXF76541.1 - 1.2e-30 102.9 37.7 0.00018 21.1 0.0 15.9 17 0 0 17 17 16 10 Tetratricopeptide repeat TPR_19 PF14559.1 EXF76541.1 - 4.1e-29 100.6 23.7 2.9e-05 24.2 0.0 11.8 9 3 3 12 12 12 7 Tetratricopeptide repeat TPR_1 PF00515.23 EXF76541.1 - 1.8e-28 96.9 29.2 4.1e-06 26.1 0.0 13.9 14 0 0 14 14 13 8 Tetratricopeptide repeat TPR_17 PF13431.1 EXF76541.1 - 1.5e-26 90.3 13.2 0.074 13.2 0.0 15.3 15 0 0 15 15 14 4 Tetratricopeptide repeat TPR_12 PF13424.1 EXF76541.1 - 6.1e-24 83.7 35.3 2e-05 24.4 0.1 12.0 7 3 8 15 15 15 7 Tetratricopeptide repeat TPR_8 PF13181.1 EXF76541.1 - 1.4e-14 52.6 23.1 0.02 14.6 0.0 12.4 13 1 1 14 14 14 4 Tetratricopeptide repeat TPR_6 PF13174.1 EXF76541.1 - 2.3e-10 40.2 21.8 0.38 11.3 0.0 14.5 18 0 0 18 18 16 2 Tetratricopeptide repeat Apc3 PF12895.2 EXF76541.1 - 3.8e-10 39.7 18.4 0.0097 16.0 0.1 9.5 8 2 3 11 11 11 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EXF76541.1 - 2.1e-09 37.0 5.5 0.4 10.5 0.8 7.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.1 EXF76541.1 - 1.7e-08 33.6 29.0 0.0046 16.6 0.0 12.7 14 1 0 14 14 13 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EXF76541.1 - 0.004 16.9 0.1 2 8.3 0.0 4.7 6 0 0 6 6 4 1 Fis1 C-terminal tetratricopeptide repeat Coatomer_WDAD PF04053.9 EXF76541.1 - 0.016 14.0 0.0 0.037 12.8 0.0 1.5 1 0 0 1 1 1 0 Coatomer WD associated region ChAPs PF09295.5 EXF76541.1 - 0.022 13.5 1.5 11 4.6 0.0 3.8 5 0 0 5 5 5 0 ChAPs (Chs5p-Arf1p-binding proteins) PPTA PF01239.17 EXF76541.1 - 0.097 12.0 0.2 13 5.3 0.0 3.4 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat HemY_N PF07219.8 EXF76541.1 - 0.11 12.0 3.1 3.1 7.3 0.0 4.3 4 1 1 5 5 5 0 HemY protein N-terminus Pkinase PF00069.20 EXF76542.1 - 4.8e-66 222.5 0.0 7.1e-66 222.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF76542.1 - 1.4e-47 162.0 0.0 2.2e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF76542.1 - 7.2e-09 35.0 0.0 2.9e-07 29.7 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EXF76542.1 - 0.0062 15.6 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EXF76542.1 - 0.16 11.6 0.0 0.33 10.6 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family p450 PF00067.17 EXF76543.1 - 9.8e-62 208.9 0.0 1.4e-61 208.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Epimerase PF01370.16 EXF76544.1 - 3.1e-13 49.7 0.0 5e-13 49.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF76544.1 - 2.6e-12 47.1 0.3 4.2e-12 46.4 0.1 1.4 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EXF76544.1 - 1.8e-07 30.1 0.3 1.7e-06 26.9 0.2 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EXF76544.1 - 2.8e-06 26.7 0.5 4.1e-06 26.2 0.3 1.3 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EXF76544.1 - 5.8e-06 25.3 0.0 0.027 13.3 0.0 2.2 2 1 0 2 2 2 2 RmlD substrate binding domain NAD_binding_4 PF07993.7 EXF76544.1 - 0.00082 18.3 0.2 0.0024 16.8 0.0 1.8 1 1 1 2 2 2 1 Male sterility protein adh_short PF00106.20 EXF76544.1 - 0.0035 17.2 0.2 0.0094 15.8 0.1 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF76544.1 - 0.01 15.4 0.1 0.029 14.0 0.1 1.9 1 1 0 1 1 1 0 KR domain TrkA_N PF02254.13 EXF76544.1 - 0.053 13.5 0.0 0.1 12.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DapB_N PF01113.15 EXF76544.1 - 0.054 13.4 0.2 0.1 12.5 0.1 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Cellulase PF00150.13 EXF76545.1 - 9.4e-12 44.7 2.8 3.2e-09 36.4 0.8 2.5 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_35 PF01301.14 EXF76545.1 - 0.028 13.7 0.2 0.051 12.9 0.1 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 35 MAGUK_N_PEST PF10608.4 EXF76545.1 - 0.11 12.8 0.5 0.26 11.7 0.3 1.5 1 0 0 1 1 1 0 Polyubiquitination (PEST) N-terminal domain of MAGUK Sugar_tr PF00083.19 EXF76546.1 - 1.9e-60 204.7 11.7 2.2e-31 108.9 1.6 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EXF76546.1 - 3.9e-14 52.1 31.5 5.1e-09 35.3 5.6 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily Ank_2 PF12796.2 EXF76547.1 - 5.8e-26 90.6 1.5 1.2e-10 41.5 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EXF76547.1 - 1.1e-19 70.3 1.3 8.4e-07 29.3 0.0 5.0 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EXF76547.1 - 4.8e-17 60.8 2.4 2.6e-06 26.9 0.0 6.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 EXF76547.1 - 1.1e-15 57.2 2.6 0.00029 20.9 0.0 4.9 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF76547.1 - 6.8e-12 44.4 0.0 0.00088 19.2 0.0 5.9 5 0 0 5 5 5 2 Ankyrin repeat TPR_12 PF13424.1 EXF76547.1 - 0.00018 21.4 0.2 0.00018 21.4 0.1 2.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EXF76547.1 - 0.0042 17.5 1.7 0.11 13.1 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EXF76547.1 - 0.006 16.8 1.2 0.03 14.6 0.1 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EXF76547.1 - 0.0072 16.1 0.3 0.025 14.4 0.0 2.1 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_8 PF13181.1 EXF76547.1 - 0.01 15.5 0.0 0.03 14.0 0.0 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EXF76547.1 - 0.011 15.3 0.2 0.095 12.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 EXF76547.1 - 0.013 15.2 0.5 0.45 10.3 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat RPN7 PF10602.4 EXF76547.1 - 0.015 14.7 0.5 0.089 12.1 0.2 2.3 2 0 0 2 2 2 0 26S proteasome subunit RPN7 TPR_10 PF13374.1 EXF76547.1 - 0.031 14.2 0.7 0.1 12.5 0.1 2.1 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_MLP1_2 PF07926.7 EXF76547.1 - 0.064 13.0 2.4 0.084 12.6 0.2 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein TPR_7 PF13176.1 EXF76547.1 - 0.073 12.8 0.0 0.31 10.9 0.0 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat V_ATPase_I PF01496.14 EXF76547.1 - 1.8 6.3 3.4 1.8 6.3 0.8 1.8 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family HET PF06985.6 EXF76548.1 - 1e-31 109.9 0.0 1.7e-31 109.2 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ATP-synt_C PF00137.16 EXF76549.1 - 2.5e-16 59.2 10.5 4.8e-16 58.4 7.3 1.5 1 0 0 1 1 1 1 ATP synthase subunit C UPF0254 PF06787.6 EXF76549.1 - 0.022 14.2 0.2 0.028 13.9 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) TFIIH_BTF_p62_N PF08567.6 EXF76549.1 - 0.045 13.4 0.3 0.061 12.9 0.2 1.3 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain MFS_3 PF05977.8 EXF76549.1 - 0.17 9.9 5.4 0.2 9.7 3.7 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector AFP PF02420.10 EXF76550.1 - 0.25 11.5 2.5 55 4.4 0.0 3.7 3 0 0 3 3 3 0 Insect antifreeze protein repeat Ctr PF04145.10 EXF76551.1 - 3.6e-26 91.9 3.1 4.4e-26 91.6 2.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family SRF-TF PF00319.13 EXF76552.1 - 1.6e-23 81.6 0.3 2.2e-23 81.2 0.2 1.2 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) CDC45 PF02724.9 EXF76552.1 - 0.029 12.4 0.3 0.034 12.1 0.2 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3246 PF11596.3 EXF76552.1 - 0.069 12.4 0.3 0.093 12.0 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) Fasciclin PF02469.17 EXF76554.1 - 1.1e-17 64.2 0.0 1.4e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Fasciclin domain Melibiase PF02065.13 EXF76555.1 - 2.3e-16 59.4 0.4 4.3e-08 32.2 0.0 2.1 2 0 0 2 2 2 2 Melibiase Glyco_hydro_88 PF07470.8 EXF76555.1 - 4.5e-14 52.2 1.8 4.8e-14 52.1 0.3 1.7 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 Raffinose_syn PF05691.7 EXF76555.1 - 0.00029 18.5 0.0 0.00043 17.9 0.0 1.1 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 Fungal_trans PF04082.13 EXF76556.1 - 1.9e-11 43.3 3.1 2.3e-09 36.5 0.1 2.4 1 1 1 2 2 2 2 Fungal specific transcription factor domain MFS_1 PF07690.11 EXF76557.1 - 2e-21 76.1 28.6 1.9e-12 46.6 3.8 2.3 2 1 1 3 3 3 2 Major Facilitator Superfamily 2TM PF13239.1 EXF76557.1 - 0.054 13.5 0.2 0.054 13.5 0.2 4.7 5 0 0 5 5 5 0 2TM domain LamB_YcsF PF03746.11 EXF76558.1 - 8.6e-70 234.5 0.0 1e-69 234.2 0.0 1.1 1 0 0 1 1 1 1 LamB/YcsF family AHS2 PF02626.10 EXF76559.1 - 7.4e-73 245.1 0.0 1.1e-72 244.6 0.0 1.2 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 EXF76559.1 - 1.2e-53 181.5 0.1 3e-53 180.2 0.0 1.6 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EXF76559.1 - 6.7e-37 125.9 0.2 2e-36 124.4 0.0 2.0 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EXF76559.1 - 1.1e-31 108.9 0.0 2.2e-31 107.9 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain AHS1 PF02682.11 EXF76559.1 - 4.6e-31 107.8 0.0 1.3e-30 106.3 0.0 1.8 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 ATP-grasp_4 PF13535.1 EXF76559.1 - 2.1e-12 47.1 0.1 4.1e-12 46.2 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EXF76559.1 - 6.9e-11 41.4 0.0 1.1e-09 37.5 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl PF00364.17 EXF76559.1 - 3.3e-09 36.2 5.7 1.6e-08 34.0 1.9 3.2 4 0 0 4 4 4 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.8 EXF76559.1 - 1.2e-05 24.8 0.0 3e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EXF76559.1 - 0.00098 18.5 0.0 0.0022 17.3 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.1 EXF76559.1 - 0.011 14.9 0.0 0.022 14.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Zn_clus PF00172.13 EXF76560.1 - 4.2e-10 39.3 6.8 7.4e-10 38.5 4.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF76560.1 - 1.9e-08 33.4 0.0 4.8e-08 32.1 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.19 EXF76561.1 - 7.6e-28 97.1 26.0 1e-27 96.6 18.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EXF76561.1 - 2.8e-26 92.4 0.0 5.1e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EXF76561.1 - 2.3e-06 27.7 0.4 0.00023 21.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EXF76561.1 - 3.4e-05 23.3 0.0 0.00013 21.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EXF76561.1 - 7.1e-05 22.0 0.1 0.00012 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EXF76561.1 - 0.0023 17.9 0.7 0.0031 17.5 0.0 1.7 2 0 0 2 2 1 1 AAA ATPase domain SMC_N PF02463.14 EXF76561.1 - 0.0032 16.7 0.0 0.0092 15.2 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA PF00004.24 EXF76561.1 - 0.0062 16.7 0.0 0.033 14.3 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EXF76561.1 - 0.012 15.7 0.1 0.024 14.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EXF76561.1 - 0.014 16.1 0.0 0.044 14.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_19 PF13245.1 EXF76561.1 - 0.017 14.8 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 EXF76561.1 - 0.025 14.5 0.1 0.058 13.3 0.1 1.6 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.4 EXF76561.1 - 0.036 13.5 0.0 0.071 12.5 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Rad17 PF03215.10 EXF76561.1 - 0.039 12.6 0.0 0.062 11.9 0.0 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein AAA_29 PF13555.1 EXF76561.1 - 0.04 13.4 0.0 0.085 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain PDR_CDR PF06422.7 EXF76561.1 - 0.049 13.3 0.1 0.19 11.3 0.1 2.1 1 0 0 1 1 1 0 CDR ABC transporter Arch_ATPase PF01637.13 EXF76561.1 - 0.072 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase cobW PF02492.14 EXF76561.1 - 0.085 12.2 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EXF76561.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EXF76561.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EXF76561.1 - 0.11 12.4 0.1 0.31 11.0 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.7 EXF76561.1 - 0.13 11.8 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain SbcCD_C PF13558.1 EXF76561.1 - 0.14 12.0 0.0 0.35 10.8 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EXF76561.1 - 0.19 12.0 0.1 0.44 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_13 PF13166.1 EXF76561.1 - 2.3 6.5 5.1 1.4 7.3 0.1 2.3 3 0 0 3 3 3 0 AAA domain DNA_pol_A PF00476.15 EXF76562.1 - 7.5e-101 337.5 0.0 1.2e-100 336.9 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A zf-C3HC4_3 PF13920.1 EXF76563.1 - 1.3e-11 43.9 8.3 2.1e-11 43.3 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EXF76563.1 - 7.4e-11 41.7 9.5 1.2e-10 41.0 6.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EXF76563.1 - 5.4e-09 35.9 9.4 9.1e-09 35.1 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EXF76563.1 - 9.6e-08 31.6 9.6 1.7e-07 30.8 6.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EXF76563.1 - 3.6e-07 29.7 9.8 6e-07 29.0 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EXF76563.1 - 1.4e-05 24.8 3.4 2.3e-05 24.1 2.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EXF76563.1 - 0.0003 20.3 5.4 0.00054 19.4 3.7 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EXF76563.1 - 0.00055 19.6 3.1 0.00055 19.6 2.2 2.6 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.1 EXF76563.1 - 0.0023 17.4 7.0 0.0098 15.4 4.8 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 EXF76563.1 - 0.0035 17.1 8.2 0.0064 16.3 5.7 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EXF76563.1 - 0.0065 16.5 3.6 0.013 15.5 2.5 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger Ribosomal_L1 PF00687.16 EXF76563.1 - 0.013 14.8 0.2 0.02 14.2 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L1p/L10e family TerY-C PF15616.1 EXF76563.1 - 0.075 12.9 2.1 0.14 12.0 1.5 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_6 PF14835.1 EXF76563.1 - 0.097 12.4 2.6 0.18 11.6 1.8 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-MIZ PF02891.15 EXF76563.1 - 0.32 10.5 7.3 0.6 9.6 5.1 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-P11 PF03854.9 EXF76563.1 - 0.71 9.3 4.8 1.3 8.5 3.4 1.4 1 0 0 1 1 1 0 P-11 zinc finger DUF329 PF03884.9 EXF76563.1 - 1.6 8.3 5.8 0.41 10.2 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF329) zf-FCS PF06467.9 EXF76563.1 - 9.8 5.9 8.0 9.3 5.9 0.3 2.4 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif DUF3414 PF11894.3 EXF76564.1 - 0 1329.0 0.7 0 1328.7 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3414) TAN PF11640.3 EXF76566.1 - 1e-32 113.0 0.0 2.6e-31 108.4 0.0 2.6 3 0 0 3 3 3 1 Telomere-length maintenance and DNA damage repair GDPD PF03009.12 EXF76569.1 - 1.3e-68 231.3 0.0 6.4e-68 229.0 0.0 2.1 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.2 EXF76569.1 - 1.9e-31 108.2 0.5 6.6e-12 45.5 0.0 4.8 3 1 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EXF76569.1 - 4.1e-29 100.4 1.7 1.5e-09 38.1 0.1 5.8 6 0 0 6 6 6 4 Ankyrin repeats (many copies) SPX PF03105.14 EXF76569.1 - 2.6e-28 99.5 2.8 1e-16 61.5 0.3 3.5 1 1 1 2 2 2 2 SPX domain Ank PF00023.25 EXF76569.1 - 1.9e-24 84.1 1.6 2.7e-05 23.7 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EXF76569.1 - 2.1e-22 78.5 0.9 4.1e-06 26.8 0.0 5.8 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF76569.1 - 4e-16 57.5 0.4 0.0032 17.5 0.0 6.5 6 0 0 6 6 6 4 Ankyrin repeat DUF866 PF05907.8 EXF76572.1 - 8.9e-49 165.0 0.4 9.7e-49 164.9 0.3 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) PHD PF00628.24 EXF76572.1 - 0.038 13.6 0.8 0.085 12.5 0.6 1.6 1 0 0 1 1 1 0 PHD-finger DUF3716 PF12511.3 EXF76572.1 - 0.06 12.9 2.4 0.11 12.1 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3716) Cas_CXXC_CXXC PF09706.5 EXF76572.1 - 0.094 12.9 2.2 0.15 12.2 1.2 1.6 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_CXXC_CXXC) Lar_restr_allev PF14354.1 EXF76572.1 - 0.11 12.8 1.3 1.6 9.0 0.1 2.3 1 1 1 2 2 2 0 Restriction alleviation protein Lar zinc_ribbon_5 PF13719.1 EXF76572.1 - 1.2 8.7 4.3 2.4 7.8 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EXF76572.1 - 1.5 8.5 4.7 3.6 7.3 0.5 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Metallophos PF00149.23 EXF76573.1 - 1.8e-36 125.4 0.0 1.1e-31 109.8 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Smg4_UPF3 PF03467.10 EXF76574.1 - 2.1e-29 102.7 0.1 6.3e-29 101.1 0.1 1.8 1 0 0 1 1 1 1 Smg-4/UPF3 family RRM_1 PF00076.17 EXF76574.1 - 2.4e-06 27.0 0.0 0.0001 21.8 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF76574.1 - 2.8e-06 27.2 0.0 0.00024 21.0 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF76574.1 - 0.004 16.9 0.0 0.0089 15.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DHHA1 PF02272.14 EXF76574.1 - 0.019 14.6 3.7 0.069 12.8 1.8 2.6 2 0 0 2 2 2 0 DHHA1 domain IBN_N PF03810.14 EXF76575.1 - 1.9e-12 46.9 0.6 9e-11 41.5 0.2 3.0 2 0 0 2 2 2 1 Importin-beta N-terminal domain CAS_CSE1 PF03378.10 EXF76575.1 - 0.0016 16.8 0.0 0.0028 16.0 0.0 1.3 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Xpo1 PF08389.7 EXF76575.1 - 0.0027 17.6 0.0 8.3 6.3 0.0 4.2 4 0 0 4 4 4 2 Exportin 1-like protein RhoGEF PF00621.15 EXF76576.1 - 4.6e-28 98.3 2.1 8.6e-28 97.4 0.1 2.2 2 0 0 2 2 2 1 RhoGEF domain DUF3507 PF12015.3 EXF76576.1 - 0.018 14.5 0.0 0.037 13.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) Reo_sigmaC PF04582.7 EXF76576.1 - 0.096 11.8 3.2 0.15 11.1 1.2 1.9 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF2036 PF09724.4 EXF76577.1 - 9.9e-08 31.4 0.0 1.1e-07 31.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) IBR PF01485.16 EXF76578.1 - 0.0034 17.2 10.0 0.0034 17.2 6.9 3.5 2 1 1 3 3 3 2 IBR domain Rad4 PF03835.10 EXF76579.1 - 4.4e-31 107.2 0.0 2.5e-30 104.7 0.0 2.3 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EXF76579.1 - 9.6e-26 89.3 0.3 1.9e-25 88.3 0.2 1.5 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EXF76579.1 - 5.1e-17 61.1 0.1 1.2e-16 59.9 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EXF76579.1 - 7e-17 61.5 0.3 7e-17 61.5 0.2 5.0 5 0 0 5 5 5 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EXF76579.1 - 0.0048 17.0 0.2 0.029 14.5 0.1 2.5 1 1 0 1 1 1 1 Transglutaminase-like superfamily zf-AN1 PF01428.11 EXF76580.1 - 3.3e-24 84.4 21.3 3.3e-12 46.0 3.0 2.2 2 0 0 2 2 2 2 AN1-like Zinc finger IBR PF01485.16 EXF76580.1 - 0.015 15.1 2.8 0.015 15.1 1.9 2.6 2 1 0 2 2 2 0 IBR domain Transp_Tc5_C PF04236.10 EXF76580.1 - 0.038 14.2 14.2 1 9.5 4.4 2.4 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain DRP PF06044.7 EXF76580.1 - 0.42 9.5 2.1 3.5 6.5 0.2 2.4 3 0 0 3 3 3 0 Dam-replacing family MTP18 PF10558.4 EXF76581.1 - 2.8e-67 225.2 0.1 3.5e-67 224.9 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) DUF2611 PF11022.3 EXF76582.1 - 1.3e-28 98.8 0.2 1.4e-28 98.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2611) adh_short PF00106.20 EXF76583.1 - 6.3e-17 61.9 2.2 2.3e-14 53.6 0.3 2.1 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EXF76583.1 - 3.3e-07 30.1 0.3 7.6e-07 28.9 0.2 1.6 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 EXF76583.1 - 0.019 14.4 0.4 0.044 13.2 0.3 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family SGL PF08450.7 EXF76584.1 - 8.3e-08 31.8 0.0 1.1e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EXF76584.1 - 0.0012 18.8 0.0 0.0027 17.6 0.0 1.5 1 0 0 1 1 1 1 Arylesterase NHL PF01436.16 EXF76584.1 - 0.0033 17.2 0.3 2.3 8.3 0.0 2.9 2 1 0 2 2 2 2 NHL repeat Glycoamylase PF10091.4 EXF76585.1 - 0.12 11.3 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 Putative glucoamylase Thymidylat_synt PF00303.14 EXF76586.1 - 2.9e-116 387.1 0.0 3.3e-116 386.9 0.0 1.0 1 0 0 1 1 1 1 Thymidylate synthase HTH_Tnp_Tc5 PF03221.11 EXF76587.1 - 5.5e-18 64.5 1.6 3.9e-17 61.8 0.1 2.6 2 1 1 3 3 3 1 Tc5 transposase DNA-binding domain CHAD PF05235.9 EXF76587.1 - 0.007 15.9 1.2 0.018 14.6 0.8 1.7 1 0 0 1 1 1 1 CHAD domain DUF4604 PF15377.1 EXF76587.1 - 0.014 15.6 0.1 0.023 14.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) DUF3591 PF12157.3 EXF76588.1 - 1.1e-178 594.4 1.2 1.8e-178 593.6 0.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) Actin PF00022.14 EXF76589.1 - 4.6e-142 473.0 0.0 5.2e-142 472.9 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EXF76589.1 - 5.1e-07 28.6 0.0 0.0011 17.6 0.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein PIG-P PF08510.7 EXF76590.1 - 4.9e-42 142.5 0.1 6.2e-42 142.2 0.1 1.1 1 0 0 1 1 1 1 PIG-P DUF4131 PF13567.1 EXF76590.1 - 0.025 13.9 0.1 0.043 13.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DPM2 PF07297.7 EXF76590.1 - 3.1 8.1 10.2 5.7 7.3 7.1 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF485 PF04341.7 EXF76590.1 - 5.8 6.7 7.9 0.2 11.3 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF485 IBR PF01485.16 EXF76591.1 - 1.5e-08 34.3 15.5 4e-08 33.0 0.3 3.5 3 1 0 3 3 3 2 IBR domain FtsL PF04999.8 EXF76591.1 - 0.0019 17.8 0.3 0.0037 16.9 0.1 1.6 2 0 0 2 2 2 1 Cell division protein FtsL zf-C3HC4_3 PF13920.1 EXF76591.1 - 0.23 11.1 23.9 0.18 11.4 7.3 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EXF76591.1 - 0.67 9.8 22.2 0.11 12.2 7.1 2.6 2 0 0 2 2 2 0 Ring finger domain Mito_fiss_reg PF05308.6 EXF76591.1 - 5 6.4 10.6 3.1 7.1 5.6 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator Sugar_tr PF00083.19 EXF76592.1 - 2.9e-120 401.9 18.9 3.6e-120 401.5 13.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF76592.1 - 3.2e-22 78.7 36.3 2.6e-18 65.8 7.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sel1 PF08238.7 EXF76593.1 - 7.7e-44 147.1 46.8 2.2e-05 24.9 0.4 13.3 13 1 0 13 13 13 10 Sel1 repeat TPR_1 PF00515.23 EXF76593.1 - 0.38 10.4 7.3 2.4 7.9 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_2 PF07719.12 EXF76593.1 - 1.7 8.7 10.1 10 6.3 0.2 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.1 EXF76593.1 - 9.9 6.8 21.4 0.56 10.7 0.4 6.8 7 1 0 7 7 7 0 Tetratricopeptide repeat WD40 PF00400.27 EXF76594.1 - 2.4e-15 55.7 2.6 2.3e-05 24.0 0.0 5.1 5 1 0 5 5 5 4 WD domain, G-beta repeat FRG1 PF06229.7 EXF76595.1 - 6e-55 185.6 0.1 1e-54 184.9 0.1 1.3 1 0 0 1 1 1 1 FRG1-like family Fascin PF06268.8 EXF76595.1 - 0.0049 16.9 0.0 0.02 15.0 0.0 2.0 2 0 0 2 2 2 1 Fascin domain 2OG-FeII_Oxy PF03171.15 EXF76596.1 - 0.0022 18.2 0.0 0.0077 16.5 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 EXF76598.1 - 6.4e-14 51.4 0.0 1.4e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF76598.1 - 4.5e-07 29.6 9.5 1e-06 28.5 6.6 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF59 PF01883.14 EXF76599.1 - 1.8e-05 24.6 0.0 4.9e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Domain of unknown function DUF59 GTP_EFTU PF00009.22 EXF76600.1 - 5.4e-42 143.3 0.0 8.1e-42 142.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EXF76600.1 - 7.1e-28 96.5 0.0 2.7e-27 94.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EXF76600.1 - 8.7e-18 63.9 0.0 2.4e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EXF76600.1 - 5e-08 32.6 0.2 7.4e-07 28.9 0.0 2.4 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EXF76600.1 - 2.3e-07 30.8 0.1 8.7e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EXF76600.1 - 6e-05 22.9 0.1 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EXF76600.1 - 0.0016 18.8 0.0 0.0042 17.5 0.0 1.8 1 1 0 1 1 1 1 Miro-like protein Thiolase_N PF00108.18 EXF76601.1 - 1.9e-98 328.6 0.7 1.9e-98 328.6 0.5 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EXF76601.1 - 6.9e-47 157.9 0.2 1.8e-46 156.5 0.2 1.8 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EXF76601.1 - 4e-05 23.2 1.2 4e-05 23.2 0.8 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EXF76601.1 - 0.0093 15.6 1.3 0.8 9.4 0.0 2.8 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III WD40 PF00400.27 EXF76602.1 - 8.7e-10 38.1 0.1 8.9e-07 28.5 0.1 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat DUF2415 PF10313.4 EXF76602.1 - 0.00068 19.2 0.0 0.0018 17.8 0.0 1.7 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) Nucleoplasmin PF03066.10 EXF76602.1 - 0.7 9.4 4.1 1.8 8.0 2.9 1.6 1 0 0 1 1 1 0 Nucleoplasmin RXT2_N PF08595.6 EXF76602.1 - 2 8.1 4.4 1.8 8.3 1.9 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal O-FucT PF10250.4 EXF76603.1 - 8.7e-08 31.6 0.0 1.7e-06 27.4 0.0 2.3 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Ppx-GppA PF02541.11 EXF76604.1 - 4.7e-27 94.9 0.0 7.3e-26 91.0 0.0 2.0 1 1 0 1 1 1 1 Ppx/GppA phosphatase family HET PF06985.6 EXF76605.1 - 4e-32 111.2 0.6 8.2e-32 110.2 0.4 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 EXF76606.1 - 4.8e-30 104.4 38.5 4.8e-30 104.4 26.7 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily Peptidase_M19 PF01244.16 EXF76607.1 - 2.2e-100 335.6 0.0 2.6e-100 335.4 0.0 1.0 1 0 0 1 1 1 1 Membrane dipeptidase (Peptidase family M19) Zn_clus PF00172.13 EXF76608.1 - 0.0003 20.6 6.9 0.00068 19.4 4.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_92 PF07971.7 EXF76608.1 - 0.2 10.2 0.0 0.28 9.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 92 DUF4243 PF14027.1 EXF76609.1 - 3.6e-84 283.0 2.2 4.4e-84 282.7 1.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Rad17 PF03215.10 EXF76610.1 - 5e-56 190.4 0.0 8.1e-56 189.7 0.0 1.3 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA PF00004.24 EXF76610.1 - 0.0019 18.3 0.0 0.0054 16.9 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EXF76610.1 - 0.0054 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EXF76610.1 - 0.014 14.9 0.1 0.035 13.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EXF76610.1 - 0.015 16.1 0.0 0.036 14.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EXF76610.1 - 0.015 15.0 0.0 0.041 13.6 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 EXF76610.1 - 0.038 12.8 0.0 0.063 12.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 EXF76610.1 - 0.05 13.4 0.0 0.13 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EXF76610.1 - 0.051 13.2 0.1 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_18 PF13238.1 EXF76610.1 - 0.057 13.7 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EXF76610.1 - 0.059 13.3 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain UPF0079 PF02367.12 EXF76610.1 - 0.074 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 EXF76610.1 - 0.08 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF1752 PF08550.5 EXF76611.1 - 2.4e-10 39.7 4.1 5.5e-10 38.6 2.8 1.7 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) PBP1_TM PF14812.1 EXF76611.1 - 9.6 6.5 8.3 5.3 7.4 2.7 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Met_10 PF02475.11 EXF76612.1 - 3e-72 242.4 0.1 5.1e-72 241.6 0.0 1.4 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_18 PF12847.2 EXF76612.1 - 0.04 14.4 0.0 0.086 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TRM PF02005.11 EXF76612.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.3 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltransf_26 PF13659.1 EXF76612.1 - 0.14 12.1 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain 2OG-FeII_Oxy_2 PF13532.1 EXF76613.1 - 4e-29 101.8 0.0 5.4e-29 101.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EXF76613.1 - 1.3e-06 28.6 0.0 2.4e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Prenyltransf PF01255.14 EXF76614.1 - 3.2e-05 23.1 0.0 0.00039 19.6 0.0 2.0 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase Ovate PF04844.8 EXF76615.1 - 0.071 12.9 0.2 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 Transcriptional repressor, ovate Zn_clus PF00172.13 EXF76616.1 - 1.1e-09 38.0 12.5 2.1e-09 37.1 8.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF76616.1 - 1.3e-06 27.3 0.1 2.4e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain PDT PF00800.13 EXF76617.1 - 7.3e-53 178.8 0.0 3.3e-51 173.4 0.0 2.1 1 1 0 1 1 1 1 Prephenate dehydratase ACT PF01842.20 EXF76617.1 - 0.00054 19.3 0.0 0.0028 17.1 0.0 2.1 2 1 0 2 2 2 1 ACT domain SAM_2 PF07647.12 EXF76619.1 - 2.7e-18 65.5 0.1 3.4e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EXF76619.1 - 2.6e-16 59.5 0.1 3.2e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 EXF76619.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Ste50p-SAM PF09235.5 EXF76619.1 - 0.13 12.3 0.4 0.19 11.8 0.3 1.2 1 0 0 1 1 1 0 Ste50p, sterile alpha motif PGG PF13962.1 EXF76621.1 - 1.9 8.1 5.8 0.66 9.6 1.6 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF4646 PF15496.1 EXF76622.1 - 3e-05 24.0 0.7 0.15 12.1 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4646) Zn_clus PF00172.13 EXF76623.1 - 7.4e-09 35.3 12.6 1.3e-08 34.6 8.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF76623.1 - 5.7e-05 21.8 0.1 7.3e-05 21.5 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pkinase PF00069.20 EXF76624.1 - 1.4e-71 240.6 0.1 2.4e-71 239.9 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF76624.1 - 6.4e-54 182.7 0.1 1.3e-53 181.7 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EXF76624.1 - 2e-23 82.5 0.1 1.1e-22 80.2 0.0 2.4 1 0 0 1 1 1 1 P21-Rho-binding domain PH_11 PF15413.1 EXF76624.1 - 6.4e-09 36.0 0.2 1.9e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 Pleckstrin homology domain Kinase-like PF14531.1 EXF76624.1 - 1.3e-08 34.2 0.0 2.1e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EXF76624.1 - 0.0051 16.5 0.1 0.0051 16.5 0.1 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EXF76624.1 - 0.023 13.5 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 tRNA-synt_2b PF00587.20 EXF76625.1 - 8.1e-68 227.3 0.0 3e-67 225.4 0.1 1.8 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EXF76625.1 - 1.9e-21 75.8 3.1 9.6e-21 73.5 0.0 3.2 3 0 0 3 3 3 1 Anticodon binding domain RRF PF01765.14 EXF76625.1 - 0.038 13.4 0.0 0.038 13.4 0.0 2.3 2 0 0 2 2 2 0 Ribosome recycling factor Jnk-SapK_ap_N PF09744.4 EXF76625.1 - 2.4 8.1 9.4 0.27 11.2 2.6 2.1 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Brix PF04427.13 EXF76626.1 - 1.8e-37 128.8 0.6 1.8e-37 128.8 0.4 1.5 2 0 0 2 2 2 1 Brix domain Nop14 PF04147.7 EXF76626.1 - 0.028 12.3 31.7 0.04 11.8 22.0 1.1 1 0 0 1 1 1 0 Nop14-like family Sporozoite_P67 PF05642.6 EXF76626.1 - 3.6 5.3 7.4 5.2 4.8 5.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TPT PF03151.11 EXF76627.1 - 7.7e-16 58.1 11.1 7.7e-16 58.1 7.7 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EXF76627.1 - 6.5e-06 26.2 7.0 6.5e-06 26.2 4.8 2.9 2 1 1 3 3 3 1 EamA-like transporter family CRPA PF05745.6 EXF76627.1 - 2.7 7.7 6.0 0.67 9.7 0.2 2.6 3 0 0 3 3 3 0 Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA) Epimerase PF01370.16 EXF76628.1 - 4.5e-57 193.1 0.0 5.7e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EXF76628.1 - 5.6e-24 84.5 0.0 7.8e-23 80.7 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EXF76628.1 - 9.7e-22 77.0 0.1 5.6e-21 74.5 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.12 EXF76628.1 - 5.7e-20 71.3 0.0 7.9e-20 70.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EXF76628.1 - 5.9e-20 71.1 0.0 7.6e-20 70.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EXF76628.1 - 1.4e-08 34.9 0.0 2.4e-08 34.1 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EXF76628.1 - 0.018 14.9 0.0 1.2 9.0 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Methyltransf_23 PF13489.1 EXF76629.1 - 1.9e-14 53.6 0.0 3.5e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF76629.1 - 2.9e-09 37.3 0.0 6.4e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF76629.1 - 2.9e-08 33.4 0.0 1.1e-07 31.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF76629.1 - 7.9e-08 32.6 0.0 2.2e-07 31.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF76629.1 - 1.9e-06 28.4 0.1 1.6e-05 25.4 0.1 2.3 2 1 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF76629.1 - 4.9e-05 22.5 0.0 0.00039 19.6 0.0 2.2 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EXF76629.1 - 0.00051 19.1 0.0 0.00097 18.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EXF76629.1 - 0.0021 18.4 0.0 0.011 16.1 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EXF76629.1 - 0.0032 16.8 0.0 0.007 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Terminase_1 PF03354.10 EXF76629.1 - 0.11 10.8 0.6 0.16 10.3 0.4 1.1 1 0 0 1 1 1 0 Phage Terminase DUF938 PF06080.7 EXF76629.1 - 0.12 11.8 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Pep3_Vps18 PF05131.9 EXF76630.1 - 2.3e-45 153.6 0.0 5.1e-45 152.5 0.0 1.6 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EXF76630.1 - 6.9e-12 45.1 1.9 2.3e-09 37.0 0.1 3.3 3 0 0 3 3 3 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 EXF76630.1 - 0.00019 21.1 0.4 0.00019 21.1 0.3 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EXF76630.1 - 0.00087 18.9 0.4 0.00087 18.9 0.3 1.7 2 0 0 2 2 2 1 zinc-RING finger domain DUF2175 PF09943.4 EXF76630.1 - 0.0078 16.2 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2175) zf-C3HC4_2 PF13923.1 EXF76630.1 - 0.027 14.5 0.4 0.072 13.1 0.3 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 EXF76630.1 - 0.19 11.2 0.3 11 5.5 0.1 2.7 2 0 0 2 2 2 0 Rad50 zinc hook motif zf-C3HC4 PF00097.20 EXF76630.1 - 0.41 10.3 3.0 0.21 11.3 0.1 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) p450 PF00067.17 EXF76631.1 - 2.3e-74 250.6 0.0 3.2e-74 250.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Phe_tRNA-synt_N PF02912.13 EXF76631.1 - 0.096 12.4 0.3 0.18 11.5 0.2 1.4 1 0 0 1 1 1 0 Aminoacyl tRNA synthetase class II, N-terminal domain Abhydrolase_6 PF12697.2 EXF76632.1 - 1.3e-20 74.2 0.6 1.9e-20 73.7 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF76632.1 - 4.8e-10 39.3 0.1 7.9e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EXF76632.1 - 0.0058 16.8 0.1 0.031 14.5 0.1 2.0 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 EXF76632.1 - 0.01 15.3 0.0 3 7.3 0.0 2.4 2 0 0 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.8 EXF76632.1 - 0.015 14.9 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein TRP PF06011.7 EXF76633.1 - 9.4e-132 439.6 11.6 1.2e-131 439.3 8.1 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EXF76633.1 - 1.9e-38 131.6 5.5 3.1e-38 130.9 3.8 1.3 1 0 0 1 1 1 1 ML-like domain SRF-TF PF00319.13 EXF76636.1 - 4.9e-23 80.0 0.2 8.2e-23 79.4 0.1 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) zf-C2H2_4 PF13894.1 EXF76637.1 - 0.0029 17.8 7.8 0.53 10.7 0.2 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF76637.1 - 0.27 11.6 7.0 0.89 10.0 0.1 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type Fasciclin PF02469.17 EXF76638.1 - 3e-24 85.4 0.2 7.1e-17 61.6 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain GFA PF04828.9 EXF76640.1 - 7.3e-23 80.3 0.0 1e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 EXF76640.1 - 0.13 11.9 0.1 0.13 11.9 0.0 2.6 3 0 0 3 3 3 0 Nudix N-terminal DZR PF12773.2 EXF76640.1 - 0.13 12.0 2.1 0.3 10.9 0.6 2.2 2 1 0 2 2 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 EXF76640.1 - 0.16 11.4 1.1 0.26 10.8 0.0 2.0 2 0 0 2 2 2 0 zinc-ribbon domain DUF1365 PF07103.6 EXF76641.1 - 2.4e-30 105.4 0.2 6.7e-24 84.3 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF1365) UPF0029 PF01205.14 EXF76643.1 - 2.1e-22 78.8 0.0 4.6e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 Methyltransf_23 PF13489.1 EXF76643.1 - 1.5e-13 50.7 0.0 3.2e-13 49.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF76643.1 - 9.4e-05 22.0 0.0 0.07 12.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EXF76643.1 - 0.00012 22.4 0.0 0.00079 19.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF76643.1 - 0.00038 20.9 0.0 0.015 15.7 0.0 2.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF76643.1 - 0.0015 19.1 0.0 0.014 16.0 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Seipin PF06775.9 EXF76644.1 - 8.4e-49 165.7 0.1 1.2e-48 165.3 0.0 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Not1 PF04054.10 EXF76645.1 - 1.9e-106 356.1 0.0 4.4e-106 354.9 0.0 1.6 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EXF76645.1 - 7.2e-49 165.2 1.7 2.4e-48 163.5 1.2 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) FCH PF00611.18 EXF76646.1 - 9.2e-18 64.2 0.0 2.2e-17 63.0 0.0 1.7 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EXF76646.1 - 6.6e-13 47.8 0.0 1.2e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EXF76646.1 - 6.2e-12 44.8 0.0 6.7e-11 41.5 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.1 EXF76646.1 - 3.5e-11 42.4 0.0 6.8e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DOPA_dioxygen PF08883.6 EXF76647.1 - 7.3e-32 109.5 0.2 4.2e-31 107.1 0.2 1.9 1 1 0 1 1 1 1 Dopa 4,5-dioxygenase family Rad4 PF03835.10 EXF76648.1 - 3.3e-31 107.6 0.7 8.7e-31 106.2 0.5 1.7 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_3 PF10405.4 EXF76648.1 - 7.8e-25 86.4 0.2 1.8e-24 85.2 0.1 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 BHD_1 PF10403.4 EXF76648.1 - 1.7e-21 75.4 0.0 4.2e-21 74.2 0.0 1.7 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EXF76648.1 - 4e-08 33.4 0.5 1.3e-07 31.7 0.0 2.3 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 2 Transglut_core PF01841.14 EXF76648.1 - 0.00028 21.0 0.3 0.003 17.7 0.2 2.8 1 1 0 1 1 1 1 Transglutaminase-like superfamily Zn_clus PF00172.13 EXF76649.1 - 2.2e-10 40.2 12.0 3.3e-10 39.7 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF76649.1 - 0.00048 19.0 0.0 0.0012 17.7 0.0 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Dicty_REP PF05086.7 EXF76649.1 - 1 7.0 2.1 1.4 6.5 1.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein TFIIA PF03153.8 EXF76649.1 - 6.3 6.5 42.9 0.44 10.3 16.4 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Copper-fist PF00649.13 EXF76650.1 - 2.3e-22 77.8 1.6 2.3e-22 77.8 1.1 4.4 1 1 3 4 4 4 2 Copper fist DNA binding domain ApbA PF02558.11 EXF76652.1 - 2.8e-34 117.7 0.0 3.7e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EXF76652.1 - 2.7e-26 92.0 0.0 4.1e-26 91.4 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal GFO_IDH_MocA PF01408.17 EXF76652.1 - 0.1 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold PHY PF00360.15 EXF76653.1 - 2.6e-26 91.8 0.0 6.1e-26 90.6 0.0 1.6 1 0 0 1 1 1 1 Phytochrome region HATPase_c PF02518.21 EXF76653.1 - 3.9e-19 68.4 0.2 7.9e-19 67.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EXF76653.1 - 1.2e-16 60.6 0.0 5.8e-16 58.4 0.0 2.1 1 1 0 1 1 1 1 Response regulator receiver domain GAF PF01590.21 EXF76653.1 - 5.9e-16 58.9 0.0 1.8e-15 57.3 0.0 1.9 2 0 0 2 2 2 1 GAF domain HisKA PF00512.20 EXF76653.1 - 5.3e-13 48.7 0.5 2.2e-12 46.7 0.3 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_2 PF08446.6 EXF76653.1 - 3.3e-08 33.9 0.0 1.1e-07 32.2 0.0 2.0 2 0 0 2 2 2 1 PAS fold HATPase_c_3 PF13589.1 EXF76653.1 - 0.072 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase OKR_DC_1_N PF03709.10 EXF76653.1 - 0.11 12.5 0.0 0.28 11.2 0.0 1.6 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, N-terminal domain ABC_tran PF00005.22 EXF76655.1 - 1.2e-46 158.4 0.5 5.2e-25 88.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EXF76655.1 - 1.3e-25 90.1 47.2 9.1e-18 64.3 13.9 3.1 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EXF76655.1 - 8.8e-21 75.1 0.7 2.2e-05 24.5 0.0 4.3 3 1 1 4 4 4 4 AAA domain AAA_29 PF13555.1 EXF76655.1 - 9.4e-10 37.8 2.3 0.00023 20.6 0.3 3.1 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EXF76655.1 - 1.2e-06 27.9 3.5 0.23 10.6 0.0 3.5 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EXF76655.1 - 1.6e-06 28.5 5.1 0.02 15.2 0.5 2.3 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EXF76655.1 - 2.8e-05 23.3 0.8 0.071 12.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EXF76655.1 - 0.00031 20.7 1.2 0.82 9.6 0.3 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EXF76655.1 - 0.0015 17.9 0.2 0.15 11.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EXF76655.1 - 0.0037 16.3 2.5 0.49 9.4 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin AAA_22 PF13401.1 EXF76655.1 - 0.0061 16.7 0.3 2.5 8.2 0.1 2.9 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EXF76655.1 - 0.02 15.0 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_30 PF13604.1 EXF76655.1 - 0.022 14.3 0.3 9.4 5.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.1 EXF76655.1 - 0.029 13.4 0.0 7.8 5.4 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain AAA_33 PF13671.1 EXF76655.1 - 0.035 13.9 0.2 18 5.2 0.0 3.4 4 0 0 4 4 3 0 AAA domain SRP54 PF00448.17 EXF76655.1 - 0.044 13.2 1.4 9.1 5.6 0.6 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC2_membrane PF01061.19 EXF76655.1 - 0.05 12.7 49.9 0.0078 15.4 11.8 4.1 3 1 0 3 3 3 0 ABC-2 type transporter AAA_PrkA PF08298.6 EXF76655.1 - 0.058 12.0 0.0 3.2 6.3 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain AAA_19 PF13245.1 EXF76655.1 - 0.089 12.5 4.0 3.7 7.3 0.0 3.7 4 0 0 4 4 4 0 Part of AAA domain DUF87 PF01935.12 EXF76655.1 - 0.1 12.4 2.0 2.4 7.9 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function DUF87 AAA_10 PF12846.2 EXF76655.1 - 0.11 11.9 3.6 3.2 7.0 0.7 2.4 2 0 0 2 2 2 0 AAA-like domain SbcCD_C PF13558.1 EXF76655.1 - 0.11 12.3 0.2 13 5.7 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 EXF76655.1 - 0.13 11.7 0.1 1.4 8.3 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family G-alpha PF00503.15 EXF76655.1 - 0.15 10.7 0.1 2.9 6.4 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit Rad17 PF03215.10 EXF76655.1 - 0.16 10.5 0.0 7.4 5.1 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 EXF76655.1 - 0.25 11.2 2.7 57 3.6 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.1 EXF76655.1 - 0.27 11.1 0.3 19 5.1 0.2 2.6 2 0 0 2 2 2 0 AAA domain SET PF00856.23 EXF76656.1 - 0.00013 22.3 0.0 0.006 16.9 0.0 2.4 2 1 0 2 2 2 1 SET domain Toxin_54 PF15533.1 EXF76656.1 - 0.2 11.9 2.8 0.93 9.7 0.0 2.5 2 1 0 2 2 2 0 Putative toxin 54 Nup96 PF12110.3 EXF76657.1 - 9.5e-89 297.3 1.5 1.3e-88 296.8 1.0 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EXF76657.1 - 1.7e-47 160.7 0.0 3e-47 159.9 0.0 1.4 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EXF76657.1 - 3.4e-17 62.7 397.3 6.4e-10 39.2 31.9 11.5 2 2 7 9 9 9 5 Nucleoporin FG repeat region DUF309 PF03745.9 EXF76657.1 - 0.5 9.8 2.3 0.29 10.5 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF309) ENTH PF01417.15 EXF76658.1 - 2.1e-51 172.9 0.1 3.9e-51 172.1 0.1 1.4 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EXF76658.1 - 0.0024 16.6 0.0 0.0036 16.0 0.0 1.2 1 0 0 1 1 1 1 ANTH domain DUF1720 PF08226.6 EXF76658.1 - 0.0055 16.7 35.1 0.0055 16.7 24.3 5.7 2 1 2 4 4 4 1 Domain of unknown function (DUF1720) UIM PF02809.15 EXF76658.1 - 0.0067 15.9 0.8 0.025 14.1 0.3 2.3 2 0 0 2 2 2 1 Ubiquitin interaction motif VHS PF00790.14 EXF76658.1 - 0.026 14.1 0.0 0.048 13.3 0.0 1.4 1 0 0 1 1 1 0 VHS domain DUF4264 PF14084.1 EXF76658.1 - 0.077 12.3 0.1 0.13 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) DUF1510 PF07423.6 EXF76658.1 - 2.8 7.2 10.1 1.2 8.4 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) MOZ_SAS PF01853.13 EXF76659.1 - 1.3e-78 262.5 0.0 1.9e-78 262.0 0.0 1.2 1 0 0 1 1 1 1 MOZ/SAS family PHD PF00628.24 EXF76659.1 - 0.007 16.0 9.1 0.007 16.0 6.3 2.2 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.1 EXF76659.1 - 0.45 9.8 2.6 1.1 8.5 1.8 1.7 1 0 0 1 1 1 0 PHD-finger ATP_bind_3 PF01171.15 EXF76661.1 - 1.2e-17 64.0 0.0 1.9e-17 63.3 0.0 1.3 1 0 0 1 1 1 1 PP-loop family DUF2392 PF10288.4 EXF76661.1 - 0.0026 18.0 0.0 0.007 16.6 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2392) RecR PF02132.10 EXF76661.1 - 0.0049 16.2 0.4 0.0049 16.2 0.3 2.7 3 0 0 3 3 3 1 RecR protein zf-UBR PF02207.15 EXF76661.1 - 0.024 14.3 4.8 0.45 10.2 0.1 2.9 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Ribosomal_L7Ae PF01248.21 EXF76662.1 - 1.5e-20 72.4 0.2 2.5e-20 71.7 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Pro_CA PF00484.14 EXF76663.1 - 1.1e-45 155.3 0.6 1.4e-45 155.0 0.4 1.1 1 0 0 1 1 1 1 Carbonic anhydrase NTF2 PF02136.15 EXF76664.1 - 1.4e-30 106.0 0.2 1.6e-30 105.8 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4518 PF15008.1 EXF76664.1 - 0.015 14.3 0.1 0.064 12.2 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) Glyco_hydro_43 PF04616.9 EXF76665.1 - 3.9e-29 101.6 8.7 2.9e-21 75.8 2.8 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 PD40 PF07676.7 EXF76665.1 - 0.035 13.7 0.7 0.15 11.7 0.2 2.3 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat CK_II_beta PF01214.13 EXF76666.1 - 6.5e-76 253.9 0.0 1.2e-75 253.1 0.0 1.4 1 1 0 1 1 1 1 Casein kinase II regulatory subunit Spt5_N PF11942.3 EXF76666.1 - 0.0052 17.3 9.6 0.0052 17.3 6.7 2.3 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal VirE PF05272.6 EXF76666.1 - 0.15 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Virulence-associated protein E RRN3 PF05327.6 EXF76666.1 - 0.2 9.6 2.6 0.32 9.0 1.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cupin_8 PF13621.1 EXF76667.1 - 2.2e-26 92.8 0.0 2.6e-26 92.6 0.0 1.2 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EXF76667.1 - 0.0051 17.0 0.0 0.48 10.6 0.0 2.6 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_4 PF08007.7 EXF76667.1 - 0.029 13.6 0.0 0.048 12.9 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein p450 PF00067.17 EXF76668.1 - 3.6e-48 164.2 0.0 4.4e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Polysacc_synt_3 PF13440.1 EXF76669.1 - 0.0034 16.8 0.9 0.0054 16.2 0.6 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein PEPCK_ATP PF01293.15 EXF76670.1 - 2.8e-216 718.5 0.0 3.3e-216 718.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_18 PF13238.1 EXF76670.1 - 0.019 15.2 0.1 10 6.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EXF76670.1 - 0.035 13.6 0.0 0.087 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_33 PF13671.1 EXF76670.1 - 0.079 12.8 0.0 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EXF76670.1 - 0.11 12.4 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.22 EXF76671.1 - 1.8e-45 154.7 0.0 3.2e-45 153.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EXF76671.1 - 2.3e-21 75.7 0.2 7.1e-21 74.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EXF76671.1 - 5.2e-09 36.0 0.5 1.7e-08 34.4 0.3 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EXF76671.1 - 0.0007 19.5 0.0 0.0021 18.0 0.0 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EXF76671.1 - 0.087 11.4 0.6 0.16 10.6 0.4 1.4 1 0 0 1 1 1 0 G-protein alpha subunit Ran-binding PF05508.6 EXF76672.1 - 1e-100 336.5 0.0 1.3e-100 336.2 0.0 1.1 1 0 0 1 1 1 1 RanGTP-binding protein HTH_11 PF08279.7 EXF76672.1 - 0.22 11.1 0.7 0.99 9.1 0.1 2.3 2 0 0 2 2 2 0 HTH domain SNF2_N PF00176.18 EXF76673.1 - 1e-77 260.9 0.2 1.7e-77 260.1 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EXF76673.1 - 7.9e-13 48.0 0.0 3.1e-12 46.1 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD_2 PF06733.10 EXF76673.1 - 0.088 12.2 0.2 0.27 10.6 0.0 1.8 2 0 0 2 2 2 0 DEAD_2 DZR PF12773.2 EXF76673.1 - 0.13 12.0 0.7 0.3 10.9 0.5 1.5 1 0 0 1 1 1 0 Double zinc ribbon VHS PF00790.14 EXF76674.1 - 4.4e-36 123.6 0.0 1e-35 122.4 0.0 1.6 1 0 0 1 1 1 1 VHS domain SH3_1 PF00018.23 EXF76674.1 - 1.5e-16 59.4 0.1 3.8e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EXF76674.1 - 1.6e-16 59.5 0.2 1.6e-16 59.5 0.2 1.7 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EXF76674.1 - 2.7e-14 52.3 0.1 5.8e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain GAT PF03127.9 EXF76674.1 - 0.014 15.3 0.5 0.04 13.8 0.3 1.7 1 0 0 1 1 1 0 GAT domain UIM PF02809.15 EXF76674.1 - 0.074 12.6 4.3 0.2 11.3 3.0 1.8 1 0 0 1 1 1 0 Ubiquitin interaction motif TIR PF01582.15 EXF76674.1 - 0.1 12.0 0.7 0.29 10.5 0.3 1.8 2 0 0 2 2 2 0 TIR domain ATG13 PF10033.4 EXF76675.1 - 3.8e-71 239.2 0.0 6.7e-71 238.4 0.0 1.4 1 0 0 1 1 1 1 Autophagy-related protein 13 DUF3620 PF12281.3 EXF76675.1 - 0.16 11.6 0.0 0.34 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3620) RCC1 PF00415.13 EXF76676.1 - 8.6e-23 80.2 1.8 7.5e-07 29.2 0.2 5.4 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EXF76676.1 - 1.7e-13 50.5 0.0 8.2e-08 32.2 0.0 2.5 2 0 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 EXF76676.1 - 2.5e-09 37.3 0.4 3.3e-08 33.8 0.1 2.7 1 1 1 2 2 2 1 Ankyrin repeats (many copies) RCC1_2 PF13540.1 EXF76676.1 - 1.3e-08 34.1 1.2 1.3e-08 34.1 0.8 3.7 3 0 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Ank_3 PF13606.1 EXF76676.1 - 1.5e-05 24.7 0.3 0.026 14.7 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.2 EXF76676.1 - 0.0029 17.9 0.0 0.013 15.7 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EXF76676.1 - 0.0078 15.9 0.0 0.026 14.3 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.1 EXF76676.1 - 0.11 12.7 0.1 2.5 8.4 0.0 3.2 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Mito_carr PF00153.22 EXF76677.1 - 1.5e-69 229.7 2.1 2.7e-25 87.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Antimicrobial_8 PF08103.6 EXF76677.1 - 0.021 14.7 2.4 7.6 6.6 0.0 3.6 3 0 0 3 3 3 0 Uperin family Tim17 PF02466.14 EXF76677.1 - 5.1 7.1 7.2 0.24 11.4 0.3 2.4 3 1 0 3 3 3 0 Tim17/Tim22/Tim23/Pmp24 family BUD22 PF09073.5 EXF76679.1 - 1.7e-64 218.5 67.9 3.3e-60 204.3 47.1 2.9 1 1 0 1 1 1 1 BUD22 adh_short PF00106.20 EXF76680.1 - 7.9e-22 77.9 1.9 7.3e-21 74.8 1.3 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF76680.1 - 2.2e-21 76.7 0.3 1.6e-20 73.9 0.2 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF76680.1 - 3.6e-11 43.0 0.2 7e-11 42.1 0.1 1.5 1 1 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EXF76680.1 - 0.0012 17.9 0.1 0.002 17.1 0.1 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EXF76680.1 - 0.0013 18.8 0.2 0.0032 17.5 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EXF76680.1 - 0.0015 18.5 0.1 0.0044 17.0 0.0 1.7 1 1 1 2 2 2 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EXF76680.1 - 0.0067 15.3 0.0 0.017 14.0 0.0 1.6 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Pyr_redox PF00070.22 EXF76680.1 - 0.0086 16.4 0.3 0.018 15.4 0.2 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ETF PF01012.16 EXF76680.1 - 0.052 13.2 1.8 0.17 11.5 1.0 1.9 1 1 1 2 2 2 0 Electron transfer flavoprotein domain UCH_1 PF13423.1 EXF76681.1 - 1e-53 182.6 0.0 1.4e-53 182.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EXF76681.1 - 1.3e-26 93.8 0.0 2.2e-26 93.0 0.0 1.4 1 0 0 1 1 1 1 Exonuclease UCH PF00443.24 EXF76681.1 - 2.3e-05 23.6 0.0 8.4e-05 21.8 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Collagen PF01391.13 EXF76682.1 - 6.2e-10 38.4 33.6 6.9e-08 31.9 13.3 2.5 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Mito_carr PF00153.22 EXF76683.1 - 6.8e-54 179.5 6.1 2.2e-20 72.1 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TCO89 PF10452.4 EXF76684.1 - 5.1e-06 25.6 1.3 0.00036 19.5 0.0 3.3 3 0 0 3 3 3 2 TORC1 subunit TCO89 Cep57_MT_bd PF06657.8 EXF76685.1 - 0.039 13.9 1.5 0.09 12.7 1.0 1.6 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 DUF4537 PF15057.1 EXF76685.1 - 0.049 13.4 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) Rad9_Rad53_bind PF08605.5 EXF76685.1 - 0.061 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Fungal Rad9-like Rad53-binding PixA PF12306.3 EXF76685.1 - 0.071 12.9 2.1 1 9.1 0.1 2.3 2 0 0 2 2 2 0 Inclusion body protein ParA PF10609.4 EXF76686.1 - 2.4e-32 110.6 0.6 6.1e-32 109.3 0.4 1.7 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EXF76686.1 - 1.1e-15 57.5 0.1 1.6e-15 57.0 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EXF76686.1 - 2.9e-09 37.0 0.0 2e-08 34.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 EXF76686.1 - 7.8e-05 21.8 0.0 0.0001 21.4 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 EXF76686.1 - 0.00014 21.0 0.1 0.003 16.6 0.0 2.5 2 1 1 3 3 3 1 Anion-transporting ATPase Fer4_NifH PF00142.13 EXF76686.1 - 0.00065 18.9 0.0 0.095 11.8 0.0 2.3 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.1 EXF76686.1 - 0.00084 18.9 0.2 0.13 11.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EXF76686.1 - 0.025 13.9 0.8 0.09 12.1 0.6 1.9 1 1 0 1 1 1 0 AAA domain YhjQ PF06564.7 EXF76686.1 - 0.027 13.8 0.2 0.089 12.1 0.0 1.7 2 0 0 2 2 2 0 YhjQ protein AAA_19 PF13245.1 EXF76686.1 - 0.14 11.8 1.7 3.1 7.6 0.1 2.5 2 1 0 2 2 2 0 Part of AAA domain Zn_Tnp_IS1595 PF12760.2 EXF76686.1 - 0.18 11.6 0.3 0.35 10.7 0.2 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain EF-hand_7 PF13499.1 EXF76687.1 - 1e-11 44.8 0.0 1.5e-06 28.2 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EXF76687.1 - 1e-10 40.0 0.0 0.0016 17.6 0.1 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EXF76687.1 - 3e-07 29.7 0.0 0.051 13.4 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 EXF76687.1 - 9.9e-07 28.2 0.1 3e-06 26.7 0.0 1.9 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_4 PF12763.2 EXF76687.1 - 0.00039 20.1 0.0 0.022 14.4 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand GFO_IDH_MocA PF01408.17 EXF76688.1 - 5.4e-25 88.2 0.0 1.2e-24 87.0 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EXF76688.1 - 0.0002 21.6 0.0 0.0019 18.4 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain F_bP_aldolase PF01116.15 EXF76689.1 - 1.3e-96 323.1 0.0 1.4e-96 322.9 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II Chal_sti_synt_N PF00195.14 EXF76690.1 - 2.2e-23 82.7 0.3 3.4e-23 82.0 0.2 1.2 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Chal_sti_synt_C PF02797.10 EXF76690.1 - 7.3e-21 74.6 0.0 2e-20 73.2 0.0 1.6 2 0 0 2 2 2 1 Chalcone and stilbene synthases, C-terminal domain FAE1_CUT1_RppA PF08392.7 EXF76690.1 - 1.5e-06 27.5 0.6 2.2e-06 26.9 0.0 1.5 2 0 0 2 2 2 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.5 EXF76690.1 - 0.00047 20.1 0.0 0.0023 17.9 0.0 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.5 EXF76690.1 - 0.00073 19.1 1.1 0.0013 18.3 0.2 1.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III TRAUB PF08164.7 EXF76692.1 - 1e-31 108.8 2.0 1.7e-30 104.9 0.0 2.8 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal AATF-Che1 PF13339.1 EXF76692.1 - 3.8e-31 107.9 3.3 3.8e-31 107.9 2.3 2.5 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor Fungal_trans PF04082.13 EXF76693.1 - 2.2e-13 49.6 0.0 6.9e-13 48.0 0.0 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain HalX PF08663.5 EXF76693.1 - 0.061 13.3 0.1 0.15 12.0 0.1 1.6 1 0 0 1 1 1 0 HalX domain DASH_Dam1 PF08653.5 EXF76693.1 - 0.13 12.0 0.5 0.34 10.6 0.4 1.7 1 0 0 1 1 1 0 DASH complex subunit Dam1 MSP1_C PF07462.6 EXF76693.1 - 0.17 10.2 0.7 0.29 9.4 0.5 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Esterase_phd PF10503.4 EXF76694.1 - 3.9e-21 75.3 0.5 4.9e-21 74.9 0.3 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EXF76694.1 - 8e-08 31.7 0.1 1.6e-07 30.7 0.1 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EXF76694.1 - 1.2e-05 25.0 0.1 1.7e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF76694.1 - 0.00062 19.7 0.2 0.0011 18.8 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EXF76694.1 - 0.00079 18.2 0.1 0.0013 17.5 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_2 PF02230.11 EXF76694.1 - 0.0018 17.7 0.0 0.039 13.3 0.0 2.4 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EXF76694.1 - 0.012 15.1 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EXF76694.1 - 0.021 14.4 0.2 0.039 13.5 0.1 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EXF76694.1 - 0.039 13.7 0.0 4.2 7.2 0.0 2.5 3 0 0 3 3 3 0 Putative lysophospholipase Esterase PF00756.15 EXF76694.1 - 0.068 12.5 0.1 0.097 12.0 0.1 1.3 1 0 0 1 1 1 0 Putative esterase Eno-Rase_NADH_b PF12242.3 EXF76694.1 - 0.074 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Peptidase_S9_N PF02897.10 EXF76696.1 - 0.045 12.3 0.0 0.063 11.8 0.0 1.2 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Pyr_redox_2 PF07992.9 EXF76697.1 - 1.5e-17 64.1 0.4 4.6e-16 59.3 0.1 4.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF76697.1 - 2.2e-11 43.9 1.3 1.9e-10 41.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF76697.1 - 1.5e-06 28.4 0.3 0.00049 20.2 0.1 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF76697.1 - 9.3e-05 21.4 0.1 0.00021 20.3 0.0 1.5 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 EXF76697.1 - 0.00011 21.2 0.1 0.0013 17.7 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.9 EXF76697.1 - 0.0026 16.3 5.4 0.13 10.6 0.0 3.4 3 1 1 4 4 4 2 HI0933-like protein Trp_halogenase PF04820.9 EXF76697.1 - 0.0034 16.0 0.2 3.5 6.1 0.0 3.0 2 1 0 3 3 3 1 Tryptophan halogenase DAO PF01266.19 EXF76697.1 - 0.011 14.6 0.0 0.41 9.4 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase CheB_methylest PF01339.12 EXF76697.1 - 0.063 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 CheB methylesterase NAD_binding_9 PF13454.1 EXF76697.1 - 0.19 11.4 0.7 32 4.2 0.0 3.7 3 1 1 4 4 4 0 FAD-NAD(P)-binding GIDA PF01134.17 EXF76697.1 - 0.3 9.8 5.8 1.4 7.6 0.0 3.3 4 0 0 4 4 4 0 Glucose inhibited division protein A Acetyltransf_1 PF00583.19 EXF76698.1 - 1.7e-05 24.7 0.4 3.4e-05 23.7 0.2 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF76698.1 - 0.0014 18.7 0.0 0.0063 16.6 0.0 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain NB-ARC PF00931.17 EXF76699.1 - 2.8e-16 59.2 0.0 7.5e-16 57.8 0.0 1.7 2 0 0 2 2 2 1 NB-ARC domain TPR_12 PF13424.1 EXF76699.1 - 8.4e-08 32.0 10.9 9.9e-05 22.2 0.2 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat AAA_22 PF13401.1 EXF76699.1 - 7.7e-07 29.3 0.0 3.3e-06 27.2 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EXF76699.1 - 1.5e-05 25.0 0.0 0.0003 20.8 0.0 3.0 1 1 0 1 1 1 1 AAA ATPase domain TPR_11 PF13414.1 EXF76699.1 - 0.0012 18.4 2.2 0.0079 15.8 0.5 2.9 2 0 0 2 2 2 1 TPR repeat Arch_ATPase PF01637.13 EXF76699.1 - 0.0041 16.8 1.0 0.0082 15.8 0.0 2.0 2 0 0 2 2 2 1 Archaeal ATPase NACHT PF05729.7 EXF76699.1 - 0.0055 16.3 0.0 0.014 15.0 0.0 1.7 1 0 0 1 1 1 1 NACHT domain TPR_2 PF07719.12 EXF76699.1 - 0.021 14.7 0.6 0.021 14.7 0.4 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EXF76699.1 - 0.79 9.4 4.2 1.4 8.6 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MFS_1 PF07690.11 EXF76702.1 - 7.9e-17 60.9 23.8 7.9e-17 60.9 16.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily TauD PF02668.11 EXF76703.1 - 1.1e-55 189.1 0.5 1.4e-55 188.7 0.3 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF3328 PF11807.3 EXF76704.1 - 1.2e-31 110.1 0.6 1.4e-31 109.9 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2106 PF09879.4 EXF76704.1 - 0.14 11.5 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2106) Mannosyl_trans3 PF11051.3 EXF76706.1 - 0.00046 19.6 0.0 0.00074 18.9 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative Glyco_transf_8 PF01501.15 EXF76706.1 - 0.0017 17.7 1.3 0.0042 16.4 0.9 1.9 1 1 0 1 1 1 1 Glycosyl transferase family 8 Phage_Integr_2 PF13009.1 EXF76706.1 - 0.019 13.9 0.6 0.029 13.3 0.4 1.2 1 0 0 1 1 1 0 Putative phage integrase Kelch_5 PF13854.1 EXF76708.1 - 1.7e-19 69.3 0.4 0.0046 16.8 0.0 5.4 5 0 0 5 5 5 5 Kelch motif Kelch_4 PF13418.1 EXF76708.1 - 8.3e-19 67.1 2.8 3.4e-07 29.9 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EXF76708.1 - 3.7e-15 55.3 1.7 0.00018 21.5 0.0 5.0 3 1 2 5 5 5 3 Kelch motif Kelch_3 PF13415.1 EXF76708.1 - 3.6e-14 52.4 6.3 6.9e-06 26.0 0.0 6.0 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EXF76708.1 - 4.8e-06 26.0 0.1 5.8 6.5 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.10 EXF76708.1 - 6.1e-06 25.8 1.8 0.011 15.4 0.0 4.3 4 1 1 5 5 5 2 Kelch motif HgmA PF04209.8 EXF76709.1 - 7.5e-173 574.7 0.0 8.6e-173 574.5 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase DUF3663 PF12404.3 EXF76710.1 - 0.052 13.3 0.0 0.17 11.6 0.0 1.9 2 1 0 2 2 2 0 Peptidase NAD_synthase PF02540.12 EXF76711.1 - 7.4e-22 77.4 0.0 2.8e-21 75.5 0.0 1.8 1 1 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.17 EXF76711.1 - 4.7e-20 71.7 0.0 8.3e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Asn_synthase PF00733.16 EXF76711.1 - 0.079 12.4 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Asparagine synthase ketoacyl-synt PF00109.21 EXF76712.1 - 3.5e-79 265.8 0.0 7.1e-79 264.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EXF76712.1 - 3.8e-46 157.8 0.0 7.3e-46 156.9 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EXF76712.1 - 2e-32 111.5 0.4 4.4e-32 110.4 0.3 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EXF76712.1 - 2.1e-24 87.0 0.0 1e-23 84.7 0.0 2.2 2 0 0 2 2 2 1 Thioesterase domain PP-binding PF00550.20 EXF76712.1 - 1.3e-11 44.6 0.7 3.4e-11 43.2 0.5 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_6 PF12697.2 EXF76712.1 - 6.3e-07 29.4 1.3 0.00018 21.4 0.1 3.0 2 0 0 2 2 2 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 EXF76712.1 - 1.4e-05 24.2 0.0 3.7e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 Thiolase, N-terminal domain EthD PF07110.6 EXF76713.1 - 1.2e-23 83.8 0.6 1.5e-23 83.5 0.4 1.1 1 0 0 1 1 1 1 EthD domain Methyltransf_2 PF00891.13 EXF76714.1 - 2.3e-32 112.1 0.1 8.5e-32 110.2 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase FMO-like PF00743.14 EXF76715.1 - 9.8e-15 53.7 0.0 1.2e-14 53.4 0.0 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EXF76715.1 - 0.00035 20.5 0.1 0.00039 20.3 0.1 1.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EXF76715.1 - 0.002 18.2 0.0 0.002 18.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EXF76715.1 - 0.0027 17.5 0.1 0.0035 17.1 0.1 1.2 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.9 EXF76715.1 - 0.0052 16.1 0.0 0.0095 15.3 0.0 1.4 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 EXF76715.1 - 0.01 15.7 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EXF76715.1 - 0.012 15.0 0.0 0.012 15.0 0.0 1.1 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Cu-oxidase_2 PF07731.9 EXF76716.1 - 1.9e-25 88.9 5.0 1.2e-21 76.6 0.3 3.5 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 EXF76716.1 - 5.7e-20 71.8 0.0 1.1e-19 70.8 0.0 1.5 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EXF76716.1 - 1.5e-15 56.9 0.6 7.8e-15 54.6 0.1 2.2 2 0 0 2 2 2 1 Multicopper oxidase Fasciclin PF02469.17 EXF76717.1 - 4.2e-21 75.2 0.0 6.2e-12 45.6 0.0 2.8 2 1 0 2 2 2 2 Fasciclin domain Vwaint PF14624.1 EXF76717.1 - 0.13 12.4 0.0 0.95 9.6 0.0 2.4 3 0 0 3 3 3 0 VWA / Hh protein intein-like Pam17 PF08566.5 EXF76718.1 - 2.5e-66 222.6 0.0 3.5e-66 222.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial import protein Pam17 Med3 PF11593.3 EXF76718.1 - 0.048 12.8 3.6 0.055 12.6 2.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal GCHY-1 PF02649.9 EXF76718.1 - 0.14 11.3 1.3 0.21 10.8 0.9 1.1 1 0 0 1 1 1 0 Type I GTP cyclohydrolase folE2 ThiF PF00899.16 EXF76719.1 - 8e-40 135.8 0.0 1.3e-39 135.1 0.0 1.3 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EXF76719.1 - 8.5e-22 76.5 0.3 3.1e-21 74.7 0.2 2.0 1 1 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EXF76719.1 - 1.1e-12 48.3 0.0 1.8e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Shikimate_DH PF01488.15 EXF76719.1 - 0.0002 21.4 0.1 0.0017 18.4 0.1 2.2 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EXF76719.1 - 0.0058 16.8 0.0 0.016 15.4 0.0 1.7 2 0 0 2 2 2 1 Putative NAD(P)-binding SLX9 PF15341.1 EXF76720.1 - 1.3e-38 132.1 5.1 2e-38 131.5 3.5 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein SLX9 HCO3_cotransp PF00955.16 EXF76721.1 - 1.3e-66 225.3 13.1 2.8e-36 125.2 3.5 2.1 1 1 1 2 2 2 2 HCO3- transporter family Pkinase PF00069.20 EXF76723.1 - 3.3e-71 239.4 0.0 4.8e-71 238.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF76723.1 - 1.2e-45 155.5 0.0 2e-45 154.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EXF76723.1 - 4.8e-16 58.9 0.0 2.7e-15 56.5 0.0 2.4 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EXF76723.1 - 1.6e-07 30.6 0.0 3.1e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EXF76723.1 - 0.1 12.3 5.1 0.13 12.0 0.0 3.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family DSHCT PF08148.7 EXF76723.1 - 0.12 11.5 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 DSHCT (NUC185) domain Kdo PF06293.9 EXF76723.1 - 0.16 10.9 0.1 0.56 9.2 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family KH_1 PF00013.24 EXF76724.1 - 2.3e-88 289.7 24.9 5.5e-13 48.3 0.1 13.1 13 1 0 13 13 13 9 KH domain KH_3 PF13014.1 EXF76724.1 - 6.6e-59 194.7 24.0 2.7e-10 39.6 0.5 12.1 12 0 0 12 12 12 8 KH domain KH_2 PF07650.12 EXF76724.1 - 6.6e-10 38.4 24.4 0.027 14.0 0.2 7.4 6 1 0 7 7 7 4 KH domain SLS PF14611.1 EXF76724.1 - 9e-09 35.0 8.4 0.072 12.5 0.3 6.7 3 2 4 8 8 8 3 Mitochondrial inner-membrane-bound regulator BMC PF00936.14 EXF76724.1 - 0.0011 18.6 1.1 11 5.7 0.0 4.7 5 0 0 5 5 5 2 BMC domain HAUS2 PF15003.1 EXF76724.1 - 0.018 14.1 0.0 0.043 12.8 0.0 1.6 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 KH_4 PF13083.1 EXF76724.1 - 0.15 11.6 11.7 0.21 11.2 0.1 5.5 7 0 0 7 7 7 0 KH domain AMP-binding PF00501.23 EXF76725.1 - 5.3e-78 262.2 0.0 7.2e-78 261.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EXF76725.1 - 0.052 14.4 0.1 0.17 12.8 0.0 2.0 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain Trs65 PF12735.2 EXF76725.1 - 0.16 11.2 0.0 0.31 10.3 0.0 1.4 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 Spore_YabQ PF09578.5 EXF76726.1 - 4.4 7.3 10.9 0.23 11.4 0.8 2.9 2 1 1 3 3 3 0 Spore cortex protein YabQ (Spore_YabQ) UCH PF00443.24 EXF76727.1 - 1.6e-43 148.8 0.0 2.6e-43 148.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EXF76727.1 - 1.6e-17 63.9 0.0 2.5e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Rhodanese PF00581.15 EXF76727.1 - 0.00084 19.6 0.0 0.0022 18.3 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain VHS PF00790.14 EXF76728.1 - 3.5e-40 136.8 2.1 1.1e-39 135.2 0.0 2.2 2 0 0 2 2 2 1 VHS domain FYVE PF01363.16 EXF76728.1 - 9.8e-16 57.4 4.4 1.6e-15 56.7 3.0 1.3 1 0 0 1 1 1 1 FYVE zinc finger UIM PF02809.15 EXF76728.1 - 5.9e-06 25.4 9.4 0.0085 15.5 0.5 2.8 2 0 0 2 2 2 2 Ubiquitin interaction motif zf-DHHC PF01529.15 EXF76728.1 - 0.0021 17.4 1.5 0.005 16.2 1.0 1.5 1 0 0 1 1 1 1 DHHC palmitoyltransferase His_Phos_1 PF00300.17 EXF76729.1 - 4e-16 59.5 0.8 2.1e-14 53.9 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) HTH_OrfB_IS605 PF12323.3 EXF76729.1 - 1.5 8.2 3.8 0.42 9.9 0.3 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain Cpn60_TCP1 PF00118.19 EXF76730.1 - 1.5e-148 495.4 3.0 1.7e-148 495.2 2.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Enolase_N PF03952.11 EXF76730.1 - 0.0047 16.8 2.4 1.7 8.6 0.0 3.3 3 0 0 3 3 3 2 Enolase, N-terminal domain GTP_EFTU PF00009.22 EXF76731.1 - 4.8e-48 163.0 0.1 1.8e-47 161.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain HBS1_N PF08938.5 EXF76731.1 - 1.4e-19 69.9 1.1 1.4e-19 69.9 0.7 2.0 2 0 0 2 2 2 1 HBS1 N-terminus MMR_HSR1 PF01926.18 EXF76731.1 - 6.2e-09 35.8 0.0 1.8e-07 31.1 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.20 EXF76731.1 - 1.8e-07 31.1 0.3 5.4e-07 29.6 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.12 EXF76731.1 - 2.4e-07 30.8 0.0 8.6e-07 29.0 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain Miro PF08477.8 EXF76731.1 - 3.5e-05 24.2 0.5 0.064 13.7 0.0 3.7 4 0 0 4 4 4 1 Miro-like protein Septin PF00735.13 EXF76731.1 - 0.0035 16.3 0.0 0.0068 15.4 0.0 1.4 1 0 0 1 1 1 1 Septin Ras PF00071.17 EXF76731.1 - 0.0066 15.8 0.1 0.16 11.3 0.0 2.7 2 0 0 2 2 2 1 Ras family SRPRB PF09439.5 EXF76731.1 - 0.034 13.3 0.0 2.1 7.5 0.0 2.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.18 EXF76731.1 - 0.091 12.5 1.0 3.5 7.4 0.0 3.1 2 1 1 3 3 3 0 Dynamin family FeoB_N PF02421.13 EXF76731.1 - 0.094 11.9 0.0 1.6 8.0 0.0 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B HSP70 PF00012.15 EXF76732.1 - 1.5e-268 891.6 16.0 1.8e-268 891.5 11.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EXF76732.1 - 3e-18 65.5 2.7 8.5e-17 60.7 0.5 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 EXF76732.1 - 0.00057 19.0 3.8 0.012 14.7 0.2 3.2 3 0 0 3 3 3 1 Hydantoinase/oxoprolinase DDR PF08841.5 EXF76732.1 - 0.0086 14.9 2.6 0.074 11.8 0.1 2.6 3 0 0 3 3 3 1 Diol dehydratase reactivase ATPase-like domain FtsA PF14450.1 EXF76732.1 - 8.2 6.2 11.8 13 5.6 1.8 3.7 2 2 0 2 2 2 0 Cell division protein FtsA p450 PF00067.17 EXF76734.1 - 1.1e-62 212.0 0.0 1.4e-62 211.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EXF76735.1 - 1.5e-15 57.1 4.6 1.1e-14 54.2 2.8 2.2 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EXF76735.1 - 3.4e-08 33.3 0.3 3.7e-07 30.0 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF76735.1 - 3.9e-05 22.7 1.2 9.7e-05 21.4 0.8 1.7 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF76735.1 - 5.9e-05 22.0 2.4 0.00017 20.5 1.3 1.9 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EXF76735.1 - 9.3e-05 22.3 0.0 0.00017 21.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF76735.1 - 0.00016 20.2 0.2 0.00028 19.4 0.1 1.4 1 1 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.1 EXF76735.1 - 0.0016 18.2 0.6 0.016 15.0 0.4 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 EXF76735.1 - 0.0044 16.6 0.0 0.007 15.9 0.0 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EXF76735.1 - 0.0058 15.5 2.1 0.035 13.0 0.3 2.4 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EXF76735.1 - 0.0091 16.0 0.7 0.025 14.6 0.2 1.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF76735.1 - 0.013 14.4 0.4 0.02 13.7 0.3 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.22 EXF76735.1 - 0.015 15.7 0.2 0.058 13.8 0.1 2.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF76735.1 - 0.057 12.4 0.1 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 EXF76735.1 - 0.14 11.8 1.5 0.22 11.1 0.1 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RdRP PF05183.7 EXF76736.1 - 1e-112 377.7 0.1 1.5e-112 377.1 0.1 1.3 1 0 0 1 1 1 1 RNA dependent RNA polymerase PP2C PF00481.16 EXF76738.1 - 2.3e-31 109.1 0.0 5.8e-31 107.7 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C Glyco_transf_28 PF03033.15 EXF76738.1 - 0.044 13.5 0.0 0.092 12.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 N-terminal domain Git3 PF11710.3 EXF76739.1 - 6.3e-09 35.6 1.3 8.9e-09 35.1 0.9 1.2 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Dicty_CAR PF05462.6 EXF76739.1 - 8.5e-06 24.8 3.8 8.9e-05 21.5 1.2 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor PALP PF00291.20 EXF76740.1 - 2.8e-54 184.4 0.6 3.2e-54 184.2 0.4 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme BATS PF06968.8 EXF76741.1 - 7.7e-31 105.7 0.1 2.9e-30 103.9 0.0 2.0 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.16 EXF76741.1 - 1.9e-15 57.4 0.0 3.2e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily MFS_1 PF07690.11 EXF76742.1 - 9e-44 149.6 37.6 9e-44 149.6 26.1 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF76742.1 - 5.4e-09 35.1 16.3 5.4e-09 35.1 11.3 2.7 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 EXF76742.1 - 0.0024 16.0 0.8 0.0046 15.1 0.6 1.5 1 0 0 1 1 1 1 Transmembrane secretion effector OATP PF03137.15 EXF76742.1 - 0.21 9.6 14.6 0.021 12.8 0.6 2.8 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family TrkH PF02386.11 EXF76743.1 - 1.1e-93 313.6 10.6 4.9e-91 304.9 1.9 2.3 2 0 0 2 2 2 2 Cation transport protein DUF4243 PF14027.1 EXF76743.1 - 3.7e-68 230.3 0.0 5.3e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Na_H_Exchanger PF00999.16 EXF76744.1 - 1.2e-41 142.5 13.1 3.6e-41 140.9 9.0 1.6 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family CoA_transf_3 PF02515.12 EXF76745.1 - 7.9e-26 90.4 0.0 3.1e-25 88.5 0.0 1.8 2 0 0 2 2 2 1 CoA-transferase family III Catalase PF00199.14 EXF76747.1 - 1.5e-166 553.8 0.6 1.5e-166 553.8 0.4 1.4 2 0 0 2 2 2 1 Catalase Catalase-rel PF06628.7 EXF76747.1 - 1.1e-13 50.8 0.0 2.6e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive YscO PF07321.7 EXF76747.1 - 0.062 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Type III secretion protein YscO MFS_1 PF07690.11 EXF76748.1 - 2.1e-17 62.8 33.7 1.3e-13 50.4 14.8 2.5 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF76748.1 - 0.005 15.4 4.0 0.005 15.4 2.8 3.9 3 1 0 4 4 4 3 Sugar (and other) transporter SEN1_N PF12726.2 EXF76749.1 - 1.6e-147 492.6 4.0 2.2e-147 492.1 2.7 1.2 1 0 0 1 1 1 1 SEN1 N terminal AAA_11 PF13086.1 EXF76749.1 - 4.8e-69 232.5 11.0 6.5e-69 232.0 0.4 2.9 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EXF76749.1 - 1.6e-61 207.1 0.0 3e-61 206.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EXF76749.1 - 4.4e-12 45.5 0.1 1.3e-11 44.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EXF76749.1 - 2.9e-08 33.5 0.0 2.2e-05 24.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EXF76749.1 - 6.6e-06 25.8 0.1 0.068 12.6 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EXF76749.1 - 0.033 14.3 0.1 0.92 9.6 0.0 3.0 2 0 0 2 2 2 0 AAA domain HhH-GPD PF00730.20 EXF76750.1 - 3.9e-07 30.3 0.0 8.6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DNA_methylase PF00145.12 EXF76751.1 - 2.9e-41 141.7 0.0 3.3e-30 105.3 0.0 2.2 1 1 1 2 2 2 2 C-5 cytosine-specific DNA methylase Cons_hypoth95 PF03602.10 EXF76751.1 - 0.05 12.9 0.0 0.096 12.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Pectinesterase PF01095.14 EXF76752.1 - 3.1e-27 94.9 0.0 5.3e-23 81.0 0.0 2.2 2 0 0 2 2 2 2 Pectinesterase Glyco_hydro_28 PF00295.12 EXF76753.1 - 7.3e-49 166.4 15.3 1.1e-48 165.8 10.6 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Acetyltransf_3 PF13302.1 EXF76754.1 - 1.2e-14 54.6 0.1 9.3e-14 51.7 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain POP1 PF06978.6 EXF76755.1 - 2.8e-63 212.9 14.9 2.8e-63 212.9 10.3 2.3 2 0 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EXF76755.1 - 4.5e-26 90.5 0.1 4.5e-26 90.5 0.0 2.2 2 0 0 2 2 2 1 POPLD (NUC188) domain DUF605 PF04652.11 EXF76755.1 - 0.0015 17.9 6.5 0.0015 17.9 4.5 2.0 3 0 0 3 3 3 1 Vta1 like EAF PF09816.4 EXF76756.1 - 5.2e-18 64.9 0.0 1.2e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor MmgE_PrpD PF03972.9 EXF76757.1 - 8.7e-149 495.4 0.0 1e-148 495.2 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family SH3_1 PF00018.23 EXF76758.1 - 2.5e-13 49.1 0.0 4.3e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EXF76758.1 - 2.1e-08 33.5 0.0 3.3e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EXF76758.1 - 1.7e-06 27.3 0.0 2.7e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain DUF605 PF04652.11 EXF76758.1 - 4.6 6.5 18.4 0.47 9.8 2.9 2.0 2 0 0 2 2 2 0 Vta1 like DUF4360 PF14273.1 EXF76759.1 - 2.5e-13 50.1 0.2 3e-13 49.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) DUF3405 PF11885.3 EXF76760.1 - 7.4e-176 585.2 0.7 7.4e-176 585.2 0.5 2.0 2 0 0 2 2 1 1 Protein of unknown function (DUF3405) IncA PF04156.9 EXF76760.1 - 0.048 13.2 15.1 0.074 12.6 10.4 1.2 1 0 0 1 1 1 0 IncA protein Fmp27_WPPW PF10359.4 EXF76760.1 - 0.063 11.6 20.5 0.43 8.9 11.1 2.3 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Macoilin PF09726.4 EXF76760.1 - 0.2 9.9 11.8 0.28 9.4 8.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Vfa1 PF08432.5 EXF76760.1 - 0.29 11.1 23.9 0.53 10.2 16.6 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Asp-B-Hydro_N PF05279.6 EXF76760.1 - 0.31 10.8 20.7 0.49 10.2 14.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ycf1 PF05758.7 EXF76760.1 - 0.5 8.0 10.6 0.68 7.5 7.4 1.1 1 0 0 1 1 1 0 Ycf1 Atg14 PF10186.4 EXF76760.1 - 0.68 8.8 15.7 1.1 8.1 10.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spore_coat_CotO PF14153.1 EXF76760.1 - 1.2 8.5 20.7 2 7.7 14.4 1.3 1 0 0 1 1 1 0 Spore coat protein CotO SAPS PF04499.10 EXF76760.1 - 1.3 7.5 9.7 1.9 7.0 6.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF972 PF06156.8 EXF76760.1 - 2.1 8.7 19.4 4.7 7.5 13.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) MIP-T3 PF10243.4 EXF76760.1 - 2.5 6.4 32.2 3.4 6.0 22.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 APG6 PF04111.7 EXF76760.1 - 2.5 7.0 29.3 4 6.4 20.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 HAUS6_N PF14661.1 EXF76760.1 - 3.7 6.8 17.6 6.3 6.0 12.2 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus V_ATPase_I PF01496.14 EXF76760.1 - 5.7 4.6 12.9 8 4.1 8.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YdfA_immunity PF12127.3 EXF76760.1 - 9.2 5.0 5.8 14 4.4 4.0 1.1 1 0 0 1 1 1 0 SigmaW regulon antibacterial CheF-arch PF04283.7 EXF76761.1 - 0.048 12.8 0.7 0.093 11.9 0.3 1.6 1 1 0 1 1 1 0 Chemotaxis signal transduction system protein F from archaea YfcL PF08891.6 EXF76761.1 - 0.052 13.5 0.2 15 5.6 0.0 2.4 2 0 0 2 2 2 0 YfcL protein DUF904 PF06005.7 EXF76762.1 - 0.00069 19.8 9.4 0.12 12.6 6.5 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF904) Rab5-bind PF09311.6 EXF76762.1 - 0.31 10.8 16.6 0.43 10.4 10.4 1.9 1 1 1 2 2 2 0 Rabaptin-like protein HALZ PF02183.13 EXF76762.1 - 2.2 8.0 7.5 2.6 7.8 1.0 2.5 1 1 1 2 2 2 0 Homeobox associated leucine zipper DeoC PF01791.4 EXF76764.1 - 0.0081 15.4 0.0 0.0097 15.2 0.0 1.0 1 0 0 1 1 1 1 DeoC/LacD family aldolase COesterase PF00135.23 EXF76765.1 - 1.3e-100 337.6 0.0 1.7e-100 337.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF76765.1 - 0.00015 21.3 0.6 0.0023 17.5 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Aspzincin_M35 PF14521.1 EXF76767.1 - 1.1e-21 77.9 0.4 1.4e-21 77.5 0.3 1.1 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 EXF76767.1 - 0.0011 18.4 1.2 0.31 10.4 0.1 2.3 2 1 0 2 2 2 2 Putative peptidase family DUF723 PF05265.8 EXF76769.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF723) Peptidase_C1_2 PF03051.10 EXF76770.1 - 3.8e-149 496.9 0.0 4.4e-149 496.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase C1-like family Peptidase_C1 PF00112.18 EXF76770.1 - 2.6e-07 30.7 0.0 0.00093 19.1 0.0 2.5 3 0 0 3 3 3 2 Papain family cysteine protease L27_1 PF09058.5 EXF76771.1 - 0.11 12.3 0.5 0.58 10.0 0.2 2.3 1 1 1 2 2 2 0 L27_1 NAD_binding_10 PF13460.1 EXF76773.1 - 5e-23 82.0 0.0 8.1e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EXF76773.1 - 5.5e-11 42.1 0.0 1e-10 41.2 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EXF76773.1 - 0.011 15.2 0.0 1.7 7.9 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EXF76773.1 - 0.017 14.0 0.0 0.069 12.0 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain adh_short PF00106.20 EXF76773.1 - 0.021 14.7 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase 2-Hacid_dh_C PF02826.14 EXF76773.1 - 0.051 12.7 0.0 0.099 11.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain POTRA_2 PF08479.6 EXF76773.1 - 0.091 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 POTRA domain, ShlB-type eIF-5a PF01287.15 EXF76775.1 - 7.4e-06 25.8 0.0 1.6e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold TGF_beta_GS PF08515.7 EXF76775.1 - 0.015 14.5 0.9 0.031 13.5 0.6 1.5 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif DUF3441 PF11923.3 EXF76777.1 - 1.3e-36 124.6 0.2 6.3e-36 122.3 0.1 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3441) FbpA PF05833.6 EXF76777.1 - 8.3e-31 107.0 18.1 8.3e-31 107.0 12.5 2.9 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) DUF814 PF05670.8 EXF76777.1 - 1.5e-23 82.5 0.0 4.2e-23 81.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF814) NUDIX PF00293.23 EXF76778.1 - 2.3e-12 46.7 1.3 1.6e-11 44.0 0.9 2.1 1 1 0 1 1 1 1 NUDIX domain DUF2834 PF11196.3 EXF76778.1 - 0.48 10.6 7.7 1 9.5 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2834) HET PF06985.6 EXF76779.1 - 3.3e-22 79.1 0.3 5.6e-22 78.4 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Methyltransf_23 PF13489.1 EXF76780.1 - 1.1e-21 77.2 0.0 3e-21 75.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF76780.1 - 3.3e-11 43.5 0.0 7.5e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF76780.1 - 2.1e-10 41.1 0.0 3e-09 37.4 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF76780.1 - 5.1e-10 39.7 0.0 3.5e-09 37.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF76780.1 - 6.9e-10 38.7 0.0 2.9e-08 33.4 0.0 2.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF76780.1 - 1.1e-06 28.9 0.0 2.5e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EXF76780.1 - 0.0014 17.7 0.0 0.0024 17.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EXF76780.1 - 0.0071 16.3 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 EXF76780.1 - 0.011 14.7 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 EXF76780.1 - 0.014 14.5 0.0 0.27 10.3 0.0 2.5 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family MTS PF05175.9 EXF76780.1 - 0.087 12.1 0.0 2.4 7.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_26 PF13659.1 EXF76780.1 - 0.093 12.7 0.0 0.42 10.6 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EXF76780.1 - 0.18 10.8 0.0 0.35 9.9 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 EXF76781.1 - 1e-35 123.0 0.1 1.4e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EXF76781.1 - 4.1e-05 24.1 0.0 8.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF76781.1 - 0.02 14.6 0.1 0.061 13.0 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain CheR PF01739.13 EXF76781.1 - 0.11 11.7 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain MTS PF05175.9 EXF76781.1 - 0.16 11.3 0.0 0.29 10.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain NmrA PF05368.8 EXF76782.1 - 9.9e-18 64.2 0.0 1.8e-17 63.3 0.0 1.5 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EXF76782.1 - 4.6e-09 36.0 0.0 1.4e-08 34.5 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF76782.1 - 1.6e-07 31.4 0.1 2.9e-07 30.6 0.0 1.4 2 0 0 2 2 2 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EXF76782.1 - 0.00059 20.1 0.1 0.0016 18.7 0.1 1.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EXF76782.1 - 0.0047 16.8 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EXF76782.1 - 0.0051 15.7 0.0 0.0085 15.0 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 EXF76782.1 - 0.012 15.2 0.1 0.028 14.0 0.1 1.6 1 1 0 1 1 1 0 KR domain Saccharop_dh PF03435.13 EXF76782.1 - 0.015 14.2 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DapB_N PF01113.15 EXF76782.1 - 0.085 12.7 0.0 0.19 11.6 0.0 1.6 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Shikimate_DH PF01488.15 EXF76782.1 - 0.13 12.3 0.1 0.39 10.8 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Prothymosin PF03247.9 EXF76785.1 - 0.02 15.0 7.1 0.041 14.0 5.0 1.5 1 0 0 1 1 1 0 Prothymosin/parathymosin family DUF1187 PF06688.6 EXF76785.1 - 0.24 11.5 0.0 0.24 11.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1187) Glyco_hydro_35 PF01301.14 EXF76786.1 - 1.6e-65 221.5 0.0 1.3e-64 218.6 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EXF76786.1 - 2.5e-60 202.9 1.9 5e-60 201.9 1.3 1.5 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EXF76786.1 - 1.3e-37 128.5 9.5 1.1e-18 67.5 1.2 3.3 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EXF76786.1 - 7.8e-21 73.2 0.0 4.3e-20 70.9 0.0 2.3 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_42 PF02449.10 EXF76786.1 - 1.6e-06 27.5 0.1 0.00034 19.8 0.1 2.4 1 1 1 2 2 2 2 Beta-galactosidase Cellulase PF00150.13 EXF76786.1 - 5e-06 25.9 1.7 2e-05 23.9 0.0 2.5 3 0 0 3 3 3 1 Cellulase (glycosyl hydrolase family 5) DUF1049 PF06305.6 EXF76789.1 - 0.0043 16.5 0.0 0.0079 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) Amnionless PF14828.1 EXF76789.1 - 0.0065 15.0 0.0 0.0093 14.5 0.0 1.1 1 0 0 1 1 1 1 Amnionless Trp_oprn_chp PF09534.5 EXF76789.1 - 0.0075 15.8 0.2 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF1191 PF06697.7 EXF76789.1 - 0.044 12.6 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF3042 PF11240.3 EXF76789.1 - 0.14 11.9 0.3 0.3 10.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) VSP PF03302.8 EXF76789.1 - 1 7.9 8.0 2 6.9 5.3 1.6 1 1 1 2 2 2 0 Giardia variant-specific surface protein FlgH PF02107.11 EXF76790.1 - 0.59 9.6 4.4 0.91 9.0 3.0 1.2 1 0 0 1 1 1 0 Flagellar L-ring protein SOG2 PF10428.4 EXF76790.1 - 1.1 7.7 7.1 1.2 7.7 4.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Cu-oxidase_2 PF07731.9 EXF76791.1 - 1e-42 144.9 5.7 5.2e-38 129.6 0.3 3.4 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EXF76791.1 - 8.6e-41 139.4 0.7 9.9e-36 123.0 0.1 3.3 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase_3 PF07732.10 EXF76791.1 - 1.1e-39 134.7 6.3 1.1e-37 128.3 0.1 3.3 4 0 0 4 4 4 2 Multicopper oxidase Cupredoxin_1 PF13473.1 EXF76791.1 - 0.0078 16.0 0.0 2.7 7.9 0.0 3.3 2 2 1 3 3 3 1 Cupredoxin-like domain C1q PF00386.16 EXF76791.1 - 0.12 12.3 0.1 13 5.8 0.0 2.5 2 0 0 2 2 2 0 C1q domain FTR1 PF03239.9 EXF76792.1 - 8.3e-75 251.5 10.1 1e-74 251.2 7.0 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF1616 PF07760.6 EXF76792.1 - 0.13 11.3 2.9 0.26 10.3 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1616) Wzy_C PF04932.10 EXF76792.1 - 0.29 10.9 4.7 0.51 10.0 0.5 2.4 2 0 0 2 2 2 0 O-Antigen ligase DUF4231 PF14015.1 EXF76792.1 - 2.2 8.2 10.1 1.2 9.1 1.3 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) Asparaginase PF00710.15 EXF76793.1 - 1.3e-37 129.3 0.2 6e-37 127.1 0.1 1.8 2 0 0 2 2 2 1 Asparaginase MFS_1 PF07690.11 EXF76796.1 - 7.9e-21 74.1 48.4 6.9e-15 54.6 17.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Tyrosinase PF00264.15 EXF76797.1 - 3.3e-42 145.1 0.5 5.2e-42 144.5 0.3 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase SAM_2 PF07647.12 EXF76797.1 - 0.095 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) COesterase PF00135.23 EXF76798.1 - 1e-93 314.9 0.3 1.3e-93 314.5 0.2 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF76798.1 - 1e-07 31.7 0.1 3.4e-07 30.0 0.1 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EXF76798.1 - 0.00036 19.8 0.3 0.00074 18.7 0.2 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2384 PF09722.5 EXF76798.1 - 0.045 13.6 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2384) Aminotran_1_2 PF00155.16 EXF76799.1 - 3.6e-31 108.4 0.0 8.4e-31 107.2 0.0 1.5 1 1 1 2 2 2 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EXF76799.1 - 0.013 13.8 0.0 0.02 13.1 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Aminotran_3 PF00202.16 EXF76800.1 - 3.8e-42 144.3 0.0 2.3e-22 79.3 0.0 2.7 2 1 0 2 2 2 2 Aminotransferase class-III AAA_26 PF13500.1 EXF76800.1 - 1.2e-29 103.3 0.0 2.1e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF3112 PF11309.3 EXF76802.1 - 0.0086 15.8 0.1 0.02 14.7 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3112) RskA PF10099.4 EXF76802.1 - 0.099 12.3 0.0 14 5.3 0.0 2.5 2 1 0 2 2 2 0 Anti-sigma-K factor rskA DUF805 PF05656.9 EXF76802.1 - 0.34 10.7 0.0 0.34 10.7 0.0 2.7 2 2 0 2 2 2 0 Protein of unknown function (DUF805) NAD_binding_4 PF07993.7 EXF76803.1 - 7.2e-30 103.7 0.0 1e-29 103.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EXF76803.1 - 6.3e-27 94.0 0.0 5.1e-26 91.0 0.0 2.0 2 0 0 2 2 2 1 AMP-binding enzyme Epimerase PF01370.16 EXF76803.1 - 4.5e-12 45.9 0.0 9.3e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EXF76803.1 - 7.6e-08 32.5 0.0 1.7e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EXF76803.1 - 0.0091 15.9 0.0 0.025 14.4 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 EXF76803.1 - 0.054 13.7 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 EXF76803.1 - 0.13 11.9 0.0 0.32 10.6 0.0 1.7 1 0 0 1 1 1 0 KR domain Polysacc_synt_2 PF02719.10 EXF76803.1 - 0.16 10.8 0.0 0.6 8.9 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Pex16 PF08610.5 EXF76805.1 - 4.8e-107 357.8 0.2 5.5e-107 357.6 0.1 1.0 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Fungal_trans PF04082.13 EXF76806.1 - 9.7e-26 90.1 1.4 1.1e-25 90.0 0.3 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF76806.1 - 8e-08 32.0 12.1 1.5e-07 31.1 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Brr6_like_C_C PF10104.4 EXF76807.1 - 9e-32 109.4 4.6 1.2e-31 109.0 3.2 1.1 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain PBP1_TM PF14812.1 EXF76807.1 - 1.7 8.9 9.0 1.8 8.8 2.1 3.2 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Med26 PF08711.6 EXF76808.1 - 3.3e-12 45.7 0.0 5.8e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Pkinase PF00069.20 EXF76809.1 - 4.7e-42 143.9 0.2 3.6e-25 88.6 0.2 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EXF76809.1 - 6.7e-15 54.8 0.2 2.5e-10 39.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DUF2967 PF11179.3 EXF76810.1 - 0.015 14.8 0.8 0.023 14.1 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) Ribosomal_60s PF00428.14 EXF76810.1 - 2.5 8.5 10.7 1.8 9.0 3.5 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Chromo PF00385.19 EXF76811.1 - 9.3e-06 25.2 0.2 2e-05 24.1 0.2 1.6 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Dendrin PF15498.1 EXF76813.1 - 0.46 8.9 3.5 0.48 8.8 2.5 1.1 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin Fumble PF03630.9 EXF76815.1 - 3.8e-131 436.9 0.0 3.1e-130 433.9 0.0 2.0 1 1 0 1 1 1 1 Fumble CFEM PF05730.6 EXF76817.1 - 0.00045 19.9 2.9 0.00045 19.9 2.0 2.9 2 0 0 2 2 2 1 CFEM domain Ank_5 PF13857.1 EXF76818.1 - 7.7e-07 29.1 0.1 1.9e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EXF76818.1 - 0.053 13.8 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank PF00023.25 EXF76818.1 - 0.059 13.2 0.2 0.15 11.9 0.2 1.7 1 0 0 1 1 1 0 Ankyrin repeat Ank_3 PF13606.1 EXF76818.1 - 0.15 12.4 0.0 0.67 10.3 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeat MT0933_antitox PF14013.1 EXF76819.1 - 0.00011 22.2 3.8 0.00014 21.9 2.0 1.8 2 0 0 2 2 2 1 MT0933-like antitoxin protein Fungal_trans PF04082.13 EXF76821.1 - 3.1e-15 55.7 0.2 5e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain F-box-like PF12937.2 EXF76822.1 - 0.00054 19.6 0.1 0.0014 18.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EXF76822.1 - 0.12 12.0 0.1 0.49 10.1 0.1 2.1 1 1 0 1 1 1 0 F-box domain WD40 PF00400.27 EXF76824.1 - 2.2e-34 116.1 8.4 1.6e-06 27.7 0.0 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EXF76824.1 - 1.4e-08 34.6 0.1 0.00021 21.0 0.0 2.9 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Daxx PF03344.10 EXF76824.1 - 0.14 10.5 6.3 0.2 10.1 4.4 1.1 1 0 0 1 1 1 0 Daxx Family PAS_9 PF13426.1 EXF76825.1 - 1.3e-17 64.0 0.0 2.4e-16 60.0 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EXF76825.1 - 0.01 15.6 0.0 0.1 12.3 0.0 2.3 2 0 0 2 2 2 1 PAS fold MarR_2 PF12802.2 EXF76826.1 - 0.06 13.0 0.1 0.14 11.8 0.1 1.6 1 0 0 1 1 1 0 MarR family Acetyltransf_1 PF00583.19 EXF76827.1 - 1.2e-16 60.5 0.0 1.6e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF76827.1 - 3e-07 30.4 0.1 6e-07 29.5 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EXF76827.1 - 2.7e-06 27.5 0.0 3.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EXF76827.1 - 4.1e-06 26.4 0.0 6.7e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EXF76827.1 - 1.3e-05 25.1 0.1 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EXF76827.1 - 0.0003 20.6 0.0 0.00054 19.8 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EXF76827.1 - 0.0018 18.2 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain adh_short PF00106.20 EXF76828.1 - 2.2e-27 95.9 1.4 2.8e-27 95.6 1.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF76828.1 - 4.6e-26 92.0 0.1 5.8e-26 91.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF76828.1 - 2.2e-11 43.7 1.0 3e-11 43.3 0.7 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EXF76828.1 - 0.0093 15.6 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Tim17 PF02466.14 EXF76828.1 - 0.049 13.6 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family Methyltransf_18 PF12847.2 EXF76828.1 - 0.094 13.2 0.1 0.43 11.1 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain DUF1379 PF07126.7 EXF76828.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1379) DUF1793 PF08760.6 EXF76829.1 - 2.6e-76 255.2 1.6 1.1e-75 253.2 0.5 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1793) RRM_1 PF00076.17 EXF76830.1 - 5e-21 74.1 0.0 7e-21 73.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF76830.1 - 7.9e-16 57.7 0.0 1.1e-15 57.3 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF76830.1 - 3.2e-11 42.9 0.0 4.4e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec39 PF08314.6 EXF76831.1 - 1.1e-211 704.5 0.0 1.4e-211 704.2 0.0 1.0 1 0 0 1 1 1 1 Secretory pathway protein Sec39 Ndufs5 PF10200.4 EXF76832.1 - 3.5e-05 23.6 0.0 3.8e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DUF3128 PF11326.3 EXF76832.1 - 0.0065 16.5 0.5 0.019 15.0 0.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3128) COX6B PF02297.12 EXF76832.1 - 0.021 14.8 0.7 0.031 14.2 0.5 1.3 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Adaptin_N PF01602.15 EXF76834.1 - 1.1e-139 466.1 5.6 1.3e-139 465.9 3.9 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EXF76834.1 - 7.9e-19 68.0 0.0 2e-18 66.7 0.0 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EXF76834.1 - 1.7e-05 24.9 0.8 0.41 10.9 0.0 4.2 3 2 0 3 3 3 2 HEAT repeats NAD_binding_6 PF08030.7 EXF76834.1 - 6.3e-05 22.9 0.3 0.6 9.9 0.0 3.2 3 0 0 3 3 3 2 Ferric reductase NAD binding domain Cnd1 PF12717.2 EXF76834.1 - 0.00021 21.1 2.3 0.026 14.3 0.2 3.0 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 NAD_binding_1 PF00175.16 EXF76834.1 - 0.0045 17.5 0.1 4.4 7.9 0.0 2.6 2 0 0 2 2 2 2 Oxidoreductase NAD-binding domain HEAT PF02985.17 EXF76834.1 - 0.019 14.9 2.5 11 6.3 0.0 4.6 4 1 1 5 5 5 0 HEAT repeat TIP120 PF08623.5 EXF76834.1 - 0.037 13.5 2.0 0.048 13.2 0.1 2.2 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) EF-hand_1 PF00036.27 EXF76835.1 - 6e-41 134.6 12.8 1.3e-09 36.6 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EXF76835.1 - 6.1e-36 122.3 7.0 8.5e-20 70.6 1.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EXF76835.1 - 1.7e-34 117.2 12.2 8.8e-16 57.2 0.5 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EXF76835.1 - 3.4e-30 101.1 8.4 1.5e-09 36.9 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EXF76835.1 - 1.1e-25 87.7 9.7 1.7e-06 27.0 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EXF76835.1 - 2.1e-15 56.3 0.3 2.9e-08 33.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EXF76835.1 - 4.1e-09 36.1 1.8 0.00079 19.1 0.2 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EXF76835.1 - 8.6e-09 35.4 0.1 0.0041 17.1 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EXF76835.1 - 5.9e-08 32.2 0.1 0.027 14.0 0.0 3.2 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EXF76835.1 - 7.4e-07 29.0 2.1 6e-06 26.1 0.2 2.3 2 1 0 2 2 2 1 Ca2+ insensitive EF hand TerB PF05099.8 EXF76835.1 - 0.00023 20.9 0.6 0.38 10.4 0.0 2.4 1 1 1 2 2 2 2 Tellurite resistance protein TerB Caleosin PF05042.8 EXF76835.1 - 0.00037 20.0 0.2 0.092 12.3 0.0 2.7 1 1 1 3 3 3 1 Caleosin related protein RNA_pol_Rpb4 PF03874.11 EXF76835.1 - 0.0034 17.3 0.7 1.6 8.7 0.0 2.7 3 0 0 3 3 2 1 RNA polymerase Rpb4 Tenui_NCP PF04876.7 EXF76835.1 - 0.0039 16.7 0.1 0.25 10.8 0.0 2.3 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein Toprim_2 PF13155.1 EXF76835.1 - 0.007 16.6 1.4 2.3 8.6 1.0 2.5 1 1 0 1 1 1 1 Toprim-like DUF3349 PF11829.3 EXF76835.1 - 0.053 13.9 0.5 12 6.4 0.1 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_10 PF14788.1 EXF76835.1 - 0.2 11.3 2.3 1.1 8.9 0.1 3.1 1 1 3 4 4 4 0 EF hand RloB PF13707.1 EXF76835.1 - 0.29 10.7 4.0 1 8.9 0.8 2.3 1 1 1 2 2 2 0 RloB-like protein SNARE PF05739.14 EXF76836.1 - 2.7e-19 68.6 3.3 2.7e-19 68.6 2.3 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EXF76836.1 - 2.1e-13 50.3 6.6 9.8e-13 48.1 0.3 2.3 2 0 0 2 2 2 2 Syntaxin Sporozoite_P67 PF05642.6 EXF76836.1 - 0.013 13.3 0.1 0.017 13.0 0.0 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MCPsignal PF00015.16 EXF76836.1 - 0.023 14.2 9.8 0.36 10.3 1.7 2.6 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain IncA PF04156.9 EXF76836.1 - 1.9 8.0 10.0 13 5.3 0.1 3.3 3 0 0 3 3 3 0 IncA protein PPR_2 PF13041.1 EXF76837.1 - 3.2e-05 23.8 0.0 0.0005 19.9 0.0 2.3 2 0 0 2 2 2 1 PPR repeat family PPR PF01535.15 EXF76837.1 - 0.00033 20.4 0.0 0.0081 16.0 0.0 2.7 2 0 0 2 2 2 1 PPR repeat PPR_3 PF13812.1 EXF76837.1 - 0.0086 16.2 1.1 0.27 11.6 0.0 3.8 5 0 0 5 5 5 1 Pentatricopeptide repeat domain PPR_1 PF12854.2 EXF76837.1 - 0.21 11.1 0.0 0.41 10.1 0.0 1.5 1 0 0 1 1 1 0 PPR repeat COX7a PF02238.10 EXF76838.1 - 0.11 12.2 0.1 0.2 11.4 0.1 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIa Clathrin_lg_ch PF01086.12 EXF76839.1 - 4e-72 242.7 4.8 4.5e-72 242.6 3.3 1.0 1 0 0 1 1 1 1 Clathrin light chain Methyltransf_2 PF00891.13 EXF76839.1 - 0.11 11.6 0.1 0.21 10.7 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase ATP-synt_B PF00430.13 EXF76839.1 - 0.44 10.3 8.2 0.71 9.6 5.7 1.2 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) CTD_bind PF04818.8 EXF76840.1 - 2.4e-19 69.3 0.1 6.7e-19 67.9 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CTK3 PF12243.3 EXF76840.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.5 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 ABC_membrane PF00664.18 EXF76841.1 - 1.3e-43 149.4 6.5 1.7e-43 149.0 4.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EXF76841.1 - 4.4e-33 114.4 0.0 8.8e-33 113.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EXF76841.1 - 0.00025 20.3 0.1 0.0056 15.9 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EXF76841.1 - 0.00054 19.9 0.1 0.0014 18.6 0.1 1.6 1 1 0 1 1 1 1 AAA ATPase domain ABC_ATPase PF09818.4 EXF76841.1 - 0.0038 15.8 0.2 0.0067 15.0 0.1 1.3 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_22 PF13401.1 EXF76841.1 - 0.0039 17.3 0.1 0.017 15.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.1 EXF76841.1 - 0.0065 16.4 0.9 1.1 9.2 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EXF76841.1 - 0.0091 16.8 0.0 0.023 15.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EXF76841.1 - 0.011 15.9 0.1 0.14 12.3 0.1 2.4 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EXF76841.1 - 0.014 14.8 0.0 0.04 13.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.9 EXF76841.1 - 0.05 13.3 0.1 0.22 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.1 EXF76841.1 - 0.059 13.2 0.9 0.33 10.9 0.6 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Sigma54_activ_2 PF14532.1 EXF76841.1 - 0.096 12.7 0.0 0.45 10.5 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF4131 PF13567.1 EXF76841.1 - 0.098 12.0 1.3 0.22 10.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) IstB_IS21 PF01695.12 EXF76841.1 - 0.19 11.1 0.7 1.1 8.6 0.0 2.2 2 1 0 2 2 2 0 IstB-like ATP binding protein Hydrolase_4 PF12146.3 EXF76842.1 - 1.6e-21 75.9 0.0 3.8e-21 74.7 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 EXF76842.1 - 1e-20 74.6 0.1 1.3e-20 74.2 0.1 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF76842.1 - 7.3e-13 48.5 0.0 1.1e-12 47.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF76842.1 - 0.0022 17.5 0.0 0.003 17.1 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EXF76842.1 - 0.035 13.7 0.0 0.088 12.4 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) Esterase PF00756.15 EXF76842.1 - 0.038 13.4 0.0 0.058 12.8 0.0 1.4 1 1 0 1 1 1 0 Putative esterase DUF900 PF05990.7 EXF76842.1 - 0.086 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 EXF76842.1 - 0.17 11.4 0.0 0.37 10.3 0.0 1.6 1 1 0 1 1 1 0 PGAP1-like protein Cation_efflux PF01545.16 EXF76843.1 - 1e-27 96.9 5.0 1.2e-27 96.6 3.5 1.1 1 0 0 1 1 1 1 Cation efflux family ER_lumen_recept PF00810.13 EXF76843.1 - 0.085 13.3 1.0 0.19 12.2 0.6 1.6 1 1 0 1 1 1 0 ER lumen protein retaining receptor Glyco_transf_8 PF01501.15 EXF76845.1 - 5e-37 127.5 0.0 9.2e-37 126.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EXF76845.1 - 0.002 17.5 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Mannosyltransferase putative zf-rbx1 PF12678.2 EXF76846.1 - 7.9e-12 45.1 0.7 1.4e-11 44.2 0.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EXF76846.1 - 9.7e-12 44.5 4.4 1.7e-11 43.7 3.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EXF76846.1 - 3.9e-07 29.6 3.8 1.2e-06 28.0 2.8 1.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EXF76846.1 - 3.3e-06 26.6 2.7 5.8e-06 25.8 1.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EXF76846.1 - 3.3e-06 26.7 2.1 5.8e-06 25.9 1.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EXF76846.1 - 3.4e-06 26.9 2.3 8.5e-06 25.7 1.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EXF76846.1 - 0.00052 19.6 3.1 0.0014 18.2 2.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EXF76846.1 - 0.0059 16.4 2.6 0.014 15.1 1.8 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EXF76846.1 - 0.098 12.5 1.3 0.2 11.5 0.9 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EXF76846.1 - 0.22 11.5 1.8 0.6 10.1 1.3 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_4 PF14570.1 EXF76846.1 - 0.84 9.2 2.5 1.9 8.1 1.8 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain CMD PF02627.15 EXF76847.1 - 0.00038 20.2 0.0 0.0014 18.3 0.0 1.9 3 0 0 3 3 3 1 Carboxymuconolactone decarboxylase family DUF1840 PF08895.6 EXF76849.1 - 0.06 13.3 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) zf-C2H2 PF00096.21 EXF76851.1 - 0.00022 21.4 19.3 2 8.9 0.0 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF76851.1 - 0.00024 21.2 15.9 0.16 12.3 0.0 4.5 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EXF76851.1 - 0.002 17.9 0.9 0.086 12.7 0.7 2.6 2 0 0 2 2 2 1 C2H2-type zinc finger Methyltransf_23 PF13489.1 EXF76852.1 - 5.3e-21 75.0 0.0 6.8e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF76852.1 - 1.2e-13 51.3 0.0 2.3e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF76852.1 - 2.1e-11 44.1 0.0 8.3e-11 42.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF76852.1 - 5.3e-11 42.3 0.0 1.1e-09 38.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF76852.1 - 3.4e-09 37.2 0.0 5.3e-08 33.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF76852.1 - 5.9e-09 35.3 0.0 8.8e-08 31.5 0.0 2.3 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EXF76852.1 - 2.2e-06 27.9 0.0 6.3e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF76852.1 - 3.6e-05 22.8 0.0 0.0011 18.1 0.0 2.7 3 0 0 3 3 3 1 Putative methyltransferase MTS PF05175.9 EXF76852.1 - 0.00043 19.6 0.0 0.0043 16.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EXF76852.1 - 0.0045 16.4 0.0 0.008 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EXF76852.1 - 0.014 15.4 0.0 0.075 13.0 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EXF76852.1 - 0.1 11.7 0.0 0.16 11.0 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EXF76852.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase DUF938 PF06080.7 EXF76852.1 - 0.11 11.9 0.0 4.2 6.8 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF938) WD40 PF00400.27 EXF76853.1 - 9.7e-08 31.6 4.3 1.6e-05 24.5 0.1 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat Apc4_WD40 PF12894.2 EXF76853.1 - 0.077 12.5 0.0 0.52 9.8 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Lactamase_B_3 PF13483.1 EXF76854.1 - 0.014 15.0 0.1 0.04 13.6 0.1 1.8 2 1 0 2 2 2 0 Beta-lactamase superfamily domain Fungal_trans_2 PF11951.3 EXF76855.1 - 3e-30 105.1 0.3 3.5e-30 104.8 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF76855.1 - 4.1e-08 33.0 6.5 4.1e-08 33.0 4.5 2.5 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EXF76856.1 - 8.4e-35 120.1 31.7 8.4e-35 120.1 22.0 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF76856.1 - 1.2e-10 40.6 11.0 1.2e-10 40.6 7.6 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EXF76856.1 - 2e-08 32.9 0.8 3.5e-08 32.1 0.5 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) SIS PF01380.17 EXF76857.1 - 5.5e-13 48.6 0.0 8.8e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 SIS domain SIS_2 PF13580.1 EXF76857.1 - 0.025 14.2 0.0 0.064 12.9 0.0 1.6 1 1 1 2 2 2 0 SIS domain ALO PF04030.9 EXF76858.1 - 8.2e-85 284.5 0.6 1.1e-84 284.1 0.4 1.1 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.18 EXF76858.1 - 8.6e-29 99.7 0.0 1.5e-28 98.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Aldo_ket_red PF00248.16 EXF76859.1 - 1.9e-50 171.2 0.0 3.2e-50 170.5 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family AAA_22 PF13401.1 EXF76859.1 - 8e-08 32.5 0.0 4.5e-07 30.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EXF76859.1 - 4.8e-07 29.5 0.0 1.3e-06 28.1 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EXF76859.1 - 2.8e-05 24.1 0.1 0.00043 20.3 0.0 2.9 3 1 0 3 3 3 1 AAA ATPase domain Ank PF00023.25 EXF76859.1 - 0.00022 20.8 0.0 0.0011 18.6 0.0 2.3 1 0 0 1 1 1 1 Ankyrin repeat NB-ARC PF00931.17 EXF76859.1 - 0.00022 20.1 0.0 0.00043 19.2 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain Ank_2 PF12796.2 EXF76859.1 - 0.00096 19.4 0.1 0.012 15.9 0.0 2.7 2 1 0 2 2 1 1 Ankyrin repeats (3 copies) AAA_17 PF13207.1 EXF76859.1 - 0.0063 17.3 0.2 0.039 14.7 0.0 2.4 1 1 0 2 2 2 1 AAA domain Ank_3 PF13606.1 EXF76859.1 - 0.06 13.6 0.2 1.9 8.9 0.0 3.8 3 0 0 3 3 3 0 Ankyrin repeat DUF2075 PF09848.4 EXF76859.1 - 0.098 11.6 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA PF00004.24 EXF76859.1 - 0.11 12.7 0.0 0.41 10.8 0.0 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ERG4_ERG24 PF01222.12 EXF76860.1 - 6.7e-153 509.2 4.5 7.6e-153 509.0 3.1 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EXF76860.1 - 0.00034 20.0 0.8 0.00082 18.7 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Peptidase_M28 PF04389.12 EXF76861.1 - 1.5e-39 135.6 0.0 3.2e-39 134.4 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M28 PA PF02225.17 EXF76861.1 - 1.1e-14 53.9 0.2 2.2e-13 49.7 0.0 2.7 3 0 0 3 3 3 1 PA domain Peptidase_M20 PF01546.23 EXF76861.1 - 0.00041 19.9 0.0 0.0007 19.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Glyco_hydro_61 PF03443.9 EXF76862.1 - 1.9e-47 161.8 1.4 1.5e-25 90.3 0.0 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 61 PKD PF00801.15 EXF76862.1 - 0.033 13.9 0.1 0.21 11.3 0.0 2.1 1 1 1 2 2 2 0 PKD domain Glyco_hydro_28 PF00295.12 EXF76863.1 - 2.9e-111 371.5 22.3 3.3e-111 371.3 15.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 DUF2111 PF09884.4 EXF76863.1 - 0.095 12.5 0.3 3.8 7.4 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2111) Cu-oxidase_3 PF07732.10 EXF76864.1 - 6.9e-41 138.6 3.0 8.5e-41 138.3 0.8 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EXF76864.1 - 3.9e-36 123.5 11.2 3.7e-33 113.9 0.5 3.9 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EXF76864.1 - 1.2e-30 106.4 0.2 2.5e-28 98.9 0.0 3.3 3 0 0 3 3 3 1 Multicopper oxidase Phosphoesterase PF04185.9 EXF76865.1 - 1.4e-32 113.3 4.6 8.4e-31 107.5 1.9 2.4 1 1 1 2 2 2 2 Phosphoesterase family DUF2511 PF10709.4 EXF76865.1 - 0.086 13.1 0.2 0.32 11.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2511) VIT1 PF01988.14 EXF76866.1 - 9.9e-40 136.3 3.3 6.6e-21 74.7 0.0 2.1 2 0 0 2 2 2 2 VIT family adh_short PF00106.20 EXF76867.1 - 1e-15 58.0 1.9 1.2e-15 57.7 0.4 1.8 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EXF76867.1 - 2.8e-07 30.3 0.1 5.4e-07 29.4 0.1 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF76867.1 - 1.5e-05 24.5 0.0 2.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Peptidase_S28 PF05577.7 EXF76868.1 - 6.6e-43 146.8 0.8 4.3e-42 144.2 0.5 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 EXF76868.1 - 0.00036 20.4 0.2 0.0043 16.9 0.2 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2920 PF11144.3 EXF76868.1 - 0.0025 16.8 0.0 0.0035 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Peptidase_S37 PF05576.6 EXF76868.1 - 0.012 14.1 0.5 0.52 8.7 0.0 2.3 2 0 0 2 2 2 0 PS-10 peptidase S37 NDUF_B7 PF05676.8 EXF76869.1 - 5.5e-32 108.9 1.3 6.3e-32 108.8 0.9 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EXF76869.1 - 0.00045 19.9 1.6 0.00048 19.8 0.6 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Antifungal_prot PF11402.3 EXF76869.1 - 1.8 8.8 4.9 2 8.6 2.3 1.8 1 1 1 2 2 2 0 Antifungal protein Voltage_CLC PF00654.15 EXF76870.1 - 3.2e-86 289.5 15.3 3.2e-86 289.5 10.6 1.9 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EXF76870.1 - 0.0043 16.8 0.1 0.0086 15.8 0.0 1.5 1 0 0 1 1 1 1 CBS domain LacI PF00356.16 EXF76870.1 - 0.63 9.7 4.8 0.91 9.1 0.2 2.4 2 0 0 2 2 2 0 Bacterial regulatory proteins, lacI family DUF2365 PF10157.4 EXF76871.1 - 0.065 13.1 1.7 2.2 8.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2365) FHA PF00498.21 EXF76871.1 - 0.075 13.1 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 FHA domain SGL PF08450.7 EXF76872.1 - 2.6e-26 92.5 0.0 5.7e-26 91.3 0.0 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EXF76872.1 - 0.0002 21.2 0.0 0.00047 20.0 0.0 1.6 1 0 0 1 1 1 1 Arylesterase NHL PF01436.16 EXF76872.1 - 0.013 15.4 3.3 0.58 10.2 0.0 3.6 4 0 0 4 4 4 0 NHL repeat Str_synth PF03088.11 EXF76872.1 - 0.028 14.4 0.0 0.088 12.8 0.0 1.8 1 1 0 1 1 1 0 Strictosidine synthase Abhydrolase_3 PF07859.8 EXF76873.1 - 1.1e-44 152.5 0.0 2.8e-44 151.2 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 EXF76873.1 - 0.00018 20.4 0.1 0.00045 19.0 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family RNase_H2-Ydr279 PF09468.5 EXF76874.1 - 0.76 8.9 7.2 0.91 8.6 5.0 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) Tim54 PF11711.3 EXF76874.1 - 1.3 7.5 7.0 1.5 7.3 4.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 HAD_2 PF13419.1 EXF76875.1 - 9.2e-24 84.6 0.0 1.2e-23 84.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EXF76875.1 - 8.4e-10 39.4 0.0 2.7e-09 37.7 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EXF76875.1 - 6.4e-09 35.3 0.0 1.2e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.13 EXF76875.1 - 0.0034 17.0 0.0 0.72 9.5 0.0 2.5 1 1 0 2 2 2 2 NLI interacting factor-like phosphatase Prefoldin PF02996.12 EXF76875.1 - 0.041 13.5 0.1 0.066 12.8 0.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit DLH PF01738.13 EXF76876.1 - 9e-27 93.7 0.0 1e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EXF76876.1 - 1.2e-06 28.3 0.0 1.6e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF76876.1 - 0.00014 21.1 0.0 0.00023 20.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EXF76876.1 - 0.042 13.2 0.0 0.06 12.7 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EXF76876.1 - 0.075 12.5 0.0 7.2 6.0 0.0 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold Peptidase_S8 PF00082.17 EXF76877.1 - 1.4e-39 135.9 5.0 2.1e-39 135.4 3.4 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EXF76877.1 - 1.5e-11 44.6 0.0 3.5e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 Glyco_hydro_28 PF00295.12 EXF76880.1 - 4.1e-26 91.7 1.1 5.3e-26 91.3 0.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Pectate_lyase_3 PF12708.2 EXF76880.1 - 6.2e-08 33.0 0.1 6.2e-08 33.0 0.1 3.0 2 2 1 3 3 3 1 Pectate lyase superfamily protein Sulfatase PF00884.18 EXF76881.1 - 6.8e-45 153.5 0.5 8.6e-43 146.6 0.0 2.9 2 2 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 EXF76881.1 - 3e-08 33.4 0.2 1.1e-07 31.5 0.0 1.9 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 EXF76881.1 - 0.002 18.4 0.1 0.0046 17.2 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF1501 PF07394.7 EXF76881.1 - 0.0038 16.1 0.0 0.0072 15.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1501) DUF229 PF02995.12 EXF76881.1 - 0.014 13.8 0.0 0.018 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF229) MFS_1 PF07690.11 EXF76882.1 - 4.7e-17 61.7 17.9 6.8e-17 61.2 12.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily N_methyl_3 PF13633.1 EXF76882.1 - 7.6 6.6 8.5 5.3 7.1 1.6 2.9 2 0 0 2 2 2 0 Prokaryotic N-terminal methylation site p450 PF00067.17 EXF76883.1 - 2.3e-62 211.0 0.0 3.1e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EXF76884.1 - 3.4e-43 147.6 0.0 6.4e-43 146.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EXF76884.1 - 5e-33 114.1 0.5 1.1e-30 106.5 0.0 2.6 3 0 0 3 3 3 2 Flavodoxin NAD_binding_1 PF00175.16 EXF76884.1 - 2.7e-20 72.9 0.1 8.1e-20 71.4 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain DUF2367 PF10164.4 EXF76884.1 - 0.19 11.5 0.1 0.42 10.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2367) Spore_IV_A PF09547.5 EXF76884.1 - 0.25 9.9 0.0 0.39 9.3 0.0 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Sugar_tr PF00083.19 EXF76885.1 - 1.4e-107 360.1 29.5 1.5e-107 359.9 20.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF76885.1 - 4.3e-33 114.5 25.5 4.3e-33 114.5 17.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily FNIP_M PF14637.1 EXF76885.1 - 0.08 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain Lig_chan PF00060.21 EXF76885.1 - 0.67 9.6 4.4 9.4 5.9 0.0 2.7 2 0 0 2 2 2 0 Ligand-gated ion channel BcsB PF03170.8 EXF76886.1 - 0.026 12.5 0.0 0.038 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial cellulose synthase subunit Glyco_hydro_67N PF03648.9 EXF76886.1 - 0.065 13.2 0.1 0.21 11.6 0.0 1.9 1 1 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus MFS_1 PF07690.11 EXF76887.1 - 1.8e-28 99.3 28.2 1.8e-28 99.3 19.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Glyco_hydro_38 PF01074.17 EXF76888.1 - 1.3e-88 296.7 0.1 2.4e-88 295.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EXF76888.1 - 9.2e-66 222.5 0.0 4.3e-65 220.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EXF76888.1 - 1.7e-25 89.0 0.0 4.2e-25 87.7 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Methyltransf_23 PF13489.1 EXF76889.1 - 1.1e-10 41.5 0.0 2e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF76889.1 - 1e-05 25.8 0.0 0.0001 22.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF76889.1 - 0.0012 18.4 0.0 0.003 17.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 EXF76889.1 - 0.017 14.5 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 EXF76889.1 - 0.11 13.1 0.3 0.95 10.0 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 EXF76889.1 - 0.14 12.6 0.0 1.1 9.7 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EXF76890.1 - 4.1e-19 68.8 0.0 8.3e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF76890.1 - 5.6e-12 46.2 0.0 6e-11 42.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF76890.1 - 2.8e-10 40.5 0.0 5.5e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF76890.1 - 1.6e-08 34.2 0.0 8e-08 32.0 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF76890.1 - 3.1e-06 27.5 0.0 1.4e-05 25.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EXF76890.1 - 0.00056 19.9 0.0 0.00085 19.3 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EXF76890.1 - 0.00093 19.5 0.0 0.0021 18.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF76890.1 - 0.0013 18.6 0.0 0.0069 16.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EXF76890.1 - 0.016 14.5 0.0 0.23 10.7 0.0 2.2 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain CMAS PF02353.15 EXF76890.1 - 0.018 14.1 0.0 0.035 13.1 0.0 1.4 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MTS PF05175.9 EXF76890.1 - 0.028 13.8 0.0 0.21 10.9 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 EXF76890.1 - 0.082 11.9 0.0 0.36 9.8 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Ubie_methyltran PF01209.13 EXF76890.1 - 0.13 11.3 0.0 0.61 9.1 0.0 2.0 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family Alpha_GJ PF03229.8 EXF76891.1 - 0.004 17.4 5.4 0.0076 16.5 3.7 1.4 1 0 0 1 1 1 1 Alphavirus glycoprotein J GPI-anchored PF10342.4 EXF76891.1 - 0.0044 17.4 0.5 0.0044 17.4 0.3 2.0 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Podoplanin PF05808.6 EXF76891.1 - 0.015 14.8 0.5 0.022 14.2 0.3 1.2 1 0 0 1 1 1 0 Podoplanin Glycophorin_A PF01102.13 EXF76891.1 - 0.024 14.3 0.8 0.038 13.7 0.5 1.3 1 0 0 1 1 1 0 Glycophorin A ABC2_membrane_3 PF12698.2 EXF76891.1 - 0.031 13.3 0.3 0.037 13.0 0.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Rax2 PF12768.2 EXF76891.1 - 0.041 13.1 0.0 0.06 12.5 0.0 1.2 1 0 0 1 1 1 0 Cortical protein marker for cell polarity TMEM154 PF15102.1 EXF76891.1 - 0.084 12.5 0.5 0.14 11.8 0.3 1.3 1 0 0 1 1 1 0 TMEM154 protein family Yip1 PF04893.12 EXF76891.1 - 0.35 10.3 2.4 0.27 10.7 0.3 1.7 2 0 0 2 2 2 0 Yip1 domain Ank_2 PF12796.2 EXF76892.1 - 4.2e-10 39.8 0.0 1.2e-05 25.5 0.0 2.3 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EXF76892.1 - 2.3e-05 23.9 0.1 0.0009 18.9 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 EXF76892.1 - 0.00023 21.0 0.0 0.012 15.7 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 EXF76892.1 - 0.001 19.5 0.0 0.0089 16.5 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF76892.1 - 0.0024 18.0 0.0 0.018 15.2 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Tex_N PF09371.5 EXF76892.1 - 0.15 11.3 0.0 0.26 10.5 0.0 1.2 1 0 0 1 1 1 0 Tex-like protein N-terminal domain PKD_channel PF08016.7 EXF76892.1 - 0.19 10.1 0.1 0.28 9.5 0.1 1.1 1 0 0 1 1 1 0 Polycystin cation channel DNA_primase_lrg PF04104.9 EXF76893.1 - 1.3e-77 260.5 0.0 2e-77 260.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Velvet PF11754.3 EXF76894.1 - 2.2e-61 206.9 0.0 3.4e-61 206.3 0.0 1.3 1 0 0 1 1 1 1 Velvet factor Fungal_trans_2 PF11951.3 EXF76898.1 - 6e-08 31.6 0.1 8.3e-08 31.2 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_cc PF11790.3 EXF76899.1 - 2.2e-56 190.9 1.9 2.8e-56 190.6 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Cnd2 PF05786.9 EXF76901.1 - 1.5e-209 698.1 7.0 2.1e-209 697.6 4.9 1.1 1 0 0 1 1 1 1 Condensin complex subunit 2 Na_Ca_ex PF01699.19 EXF76902.1 - 7.8e-49 164.8 36.1 8.2e-26 90.2 5.2 3.3 2 1 1 3 3 3 2 Sodium/calcium exchanger protein PMM PF03332.8 EXF76904.1 - 2.8e-103 344.2 0.3 3.2e-103 344.0 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EXF76904.1 - 7.4e-05 22.4 0.0 0.00029 20.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase WW PF00397.21 EXF76905.1 - 9.1e-09 35.0 0.1 3.5e-08 33.1 0.0 2.1 1 0 0 1 1 1 1 WW domain PhoD PF09423.5 EXF76905.1 - 0.0094 14.5 0.4 0.037 12.6 0.1 1.8 2 0 0 2 2 2 1 PhoD-like phosphatase Trypan_PARP PF05887.6 EXF76907.1 - 2.6 7.8 8.9 3.9 7.2 6.2 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Homeobox_KN PF05920.6 EXF76908.1 - 2.5e-21 75.0 0.4 6e-21 73.8 0.3 1.7 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EXF76908.1 - 4e-08 32.7 1.3 4e-08 32.7 0.9 1.7 2 0 0 2 2 2 1 Homeobox domain MFS_Mycoplasma PF07672.8 EXF76909.1 - 0.068 12.3 0.9 0.083 12.0 0.6 1.1 1 0 0 1 1 1 0 Mycoplasma MFS transporter Tetraspannin PF00335.15 EXF76910.1 - 0.006 15.8 0.7 0.0064 15.7 0.5 1.0 1 0 0 1 1 1 1 Tetraspanin family Yip1 PF04893.12 EXF76910.1 - 0.034 13.6 0.2 0.042 13.3 0.1 1.2 1 0 0 1 1 1 0 Yip1 domain TMEMspv1-c74-12 PF11044.3 EXF76910.1 - 0.042 13.3 2.2 4 7.0 0.1 2.2 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein FtsX PF02687.16 EXF76910.1 - 0.055 13.2 0.9 0.079 12.7 0.6 1.2 1 0 0 1 1 1 0 FtsX-like permease family Sod_Cu PF00080.15 EXF76911.1 - 1.4e-14 54.4 0.0 1.9e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF202 PF02656.10 EXF76913.1 - 0.0022 18.2 2.9 0.0022 18.2 2.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) zf-C2H2 PF00096.21 EXF76914.1 - 0.00017 21.7 18.6 0.0021 18.3 0.3 4.1 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EXF76914.1 - 0.008 16.2 1.3 0.024 14.7 0.9 1.8 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EXF76914.1 - 0.03 14.6 1.0 0.03 14.6 0.7 4.5 3 1 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EXF76914.1 - 0.12 12.3 0.9 0.28 11.1 0.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Glyco_hydro_31 PF01055.21 EXF76915.1 - 2.8e-98 329.6 0.5 1.3e-96 324.1 0.3 2.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EXF76915.1 - 5.7e-07 29.3 0.9 1.6e-06 27.8 0.6 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like ATS3 PF06232.6 EXF76915.1 - 0.036 13.6 0.0 0.83 9.2 0.0 2.4 2 0 0 2 2 2 0 Embryo-specific protein 3, (ATS3) PLDc_N PF13396.1 EXF76916.1 - 2.8e-11 42.9 3.7 5.3e-11 42.0 2.6 1.5 1 0 0 1 1 1 1 Phospholipase_D-nuclease N-terminal Pox_A14 PF05767.7 EXF76916.1 - 0.019 14.9 0.2 0.028 14.3 0.2 1.2 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 DUF2207 PF09972.4 EXF76916.1 - 0.038 12.5 0.3 0.041 12.4 0.2 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3309 PF11752.3 EXF76916.1 - 0.044 13.5 1.9 0.044 13.5 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) DUF4407 PF14362.1 EXF76916.1 - 0.051 12.5 2.3 0.064 12.2 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3951 PF13131.1 EXF76916.1 - 0.13 12.0 0.0 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3951) OPT PF03169.10 EXF76917.1 - 2.3e-80 270.8 16.2 1.6e-58 198.6 5.3 2.1 1 1 1 2 2 2 2 OPT oligopeptide transporter protein Neurensin PF14927.1 EXF76917.1 - 0.23 10.8 1.3 0.82 9.0 0.1 2.4 2 1 0 2 2 2 0 Neurensin Aminotran_5 PF00266.14 EXF76918.1 - 5.2e-09 35.3 0.0 5.7e-08 31.8 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EXF76918.1 - 0.011 14.7 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EXF76918.1 - 0.17 10.8 0.0 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Aminotransferase class I and II IDO PF01231.13 EXF76919.1 - 1.1e-147 491.9 0.0 1.3e-147 491.6 0.0 1.0 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase DUF1864 PF08933.6 EXF76919.1 - 6.7e-05 21.5 0.0 0.0022 16.5 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF1864) Fungal_trans PF04082.13 EXF76920.1 - 1.7e-06 27.1 0.0 3.5e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-DNL PF05180.7 EXF76920.1 - 0.093 12.4 0.3 0.23 11.1 0.2 1.6 1 0 0 1 1 1 0 DNL zinc finger Fungal_trans PF04082.13 EXF76921.1 - 2.9e-22 78.7 0.1 4.3e-22 78.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CBF_beta PF02312.12 EXF76921.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Core binding factor beta subunit BCD PF15461.1 EXF76922.1 - 0.068 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Beta-carotene 15,15'-dioxygenase Fungal_trans PF04082.13 EXF76923.1 - 2.2e-13 49.6 0.1 3.7e-13 48.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF76923.1 - 2.6e-05 24.0 8.1 6.9e-05 22.6 5.6 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF70 PF01901.11 EXF76923.1 - 0.057 12.4 0.0 0.089 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF70 Amidohydro_2 PF04909.9 EXF76924.1 - 2.5e-41 142.0 0.1 3.2e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase A_deaminase PF00962.17 EXF76925.1 - 1.7e-39 135.6 0.0 2.3e-38 131.9 0.0 2.2 1 1 0 1 1 1 1 Adenosine/AMP deaminase NmrA PF05368.8 EXF76927.1 - 1.5e-51 174.8 0.0 5.4e-51 173.0 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF76927.1 - 1.8e-09 37.8 0.0 2.6e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EXF76927.1 - 1.3e-06 27.3 0.0 1.9e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AdoHcyase_NAD PF00670.16 EXF76927.1 - 0.069 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain TrkA_N PF02254.13 EXF76927.1 - 0.097 12.6 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Abhydrolase_5 PF12695.2 EXF76928.1 - 1e-11 44.8 0.0 1.5e-11 44.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EXF76928.1 - 6.9e-07 28.7 0.0 1.3e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.6 EXF76928.1 - 0.017 14.8 0.0 0.027 14.1 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 EXF76928.1 - 0.018 13.5 0.1 0.038 12.4 0.1 1.5 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 EXF76928.1 - 0.028 13.8 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.3 EXF76928.1 - 0.15 11.8 0.0 0.4 10.5 0.0 1.7 2 0 0 2 2 2 0 Putative lysophospholipase adh_short PF00106.20 EXF76929.1 - 1.2e-17 64.3 0.1 1.9e-17 63.7 0.1 1.3 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF76929.1 - 1.3e-10 41.1 0.0 1.6e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF76929.1 - 4.8e-05 23.2 0.0 5.7e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EXF76929.1 - 0.00028 19.9 0.0 0.00036 19.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EXF76929.1 - 0.0021 17.1 0.1 0.0029 16.6 0.1 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase ThiF PF00899.16 EXF76929.1 - 0.0028 17.4 0.4 0.0041 16.9 0.3 1.5 1 1 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EXF76929.1 - 0.0038 17.3 0.0 0.0047 17.0 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EXF76929.1 - 0.087 12.2 0.1 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EXF76930.1 - 9.1e-05 22.4 0.0 0.00011 22.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EXF76930.1 - 0.00027 19.9 0.0 0.00034 19.6 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein FerA PF08165.6 EXF76930.1 - 0.03 13.9 0.3 0.086 12.5 0.2 1.7 1 1 0 1 1 1 0 FerA (NUC095) domain Shikimate_DH PF01488.15 EXF76930.1 - 0.037 14.1 0.0 0.046 13.8 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Laminin_II PF06009.7 EXF76930.1 - 0.084 12.6 0.2 0.12 12.1 0.1 1.2 1 0 0 1 1 1 0 Laminin Domain II RAI16-like PF10257.4 EXF76932.1 - 8.8e-81 271.5 1.5 1.6e-80 270.7 1.0 1.4 1 0 0 1 1 1 1 Retinoic acid induced 16-like protein TPP_enzyme_N PF02776.13 EXF76932.1 - 0.041 13.3 0.1 0.17 11.3 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain VSP PF03302.8 EXF76936.1 - 0.057 12.0 0.0 0.082 11.5 0.0 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Fungal_trans_2 PF11951.3 EXF76937.1 - 6.1e-08 31.6 0.4 1.4e-07 30.4 0.3 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF76937.1 - 1.3e-07 31.3 8.8 3.3e-07 30.0 6.1 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain OPT PF03169.10 EXF76938.1 - 1.8e-179 598.1 50.6 2.1e-179 597.9 35.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Amidohydro_4 PF13147.1 EXF76939.1 - 7.8e-18 65.4 1.3 1.8e-15 57.7 0.0 3.8 4 1 0 4 4 4 1 Amidohydrolase Amidohydro_1 PF01979.15 EXF76939.1 - 5.3e-11 42.7 0.4 6.6e-09 35.8 0.0 2.8 3 0 0 3 3 3 1 Amidohydrolase family Amidohydro_5 PF13594.1 EXF76939.1 - 3.1e-10 39.7 0.0 1.7e-07 30.9 0.0 2.7 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EXF76939.1 - 2.4e-08 33.6 0.1 1.5e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family ARL2_Bind_BART PF11527.3 EXF76941.1 - 0.03 14.1 0.2 1.1 9.0 0.1 2.0 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART DUF282 PF03380.9 EXF76941.1 - 7.4 6.4 6.4 13 5.5 0.7 2.8 2 1 1 3 3 3 0 Caenorhabditis protein of unknown function, DUF282 NAD_binding_2 PF03446.10 EXF76942.1 - 4.9e-25 88.2 0.1 7.4e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EXF76942.1 - 7.6e-09 35.6 0.1 1.2e-08 34.9 0.1 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EXF76942.1 - 0.0025 18.2 0.1 0.0076 16.6 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent FAD_binding_3 PF01494.14 EXF76943.1 - 1.9e-21 76.5 0.0 3.3e-14 52.7 0.0 2.3 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EXF76943.1 - 2e-06 26.9 0.1 5.7e-05 22.1 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF76943.1 - 2e-05 23.6 0.3 3.1e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EXF76943.1 - 3.9e-05 23.6 0.4 8.7e-05 22.4 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF76943.1 - 7.5e-05 22.6 0.1 0.00014 21.8 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF76943.1 - 0.00062 19.8 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF76943.1 - 0.0058 15.7 1.0 0.008 15.3 0.1 1.6 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 EXF76943.1 - 0.0059 15.5 0.3 0.009 14.9 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 EXF76943.1 - 0.0067 15.0 0.0 1.7 7.1 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.22 EXF76943.1 - 0.0077 16.6 0.9 0.018 15.3 0.6 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF76943.1 - 0.0082 14.6 0.5 0.017 13.5 0.4 1.5 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.16 EXF76943.1 - 0.0082 15.7 0.1 0.017 14.6 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EXF76943.1 - 0.023 13.6 0.3 0.73 8.6 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein SE PF08491.5 EXF76943.1 - 0.024 13.4 0.0 0.054 12.3 0.0 1.4 1 1 0 1 1 1 0 Squalene epoxidase FAD_oxidored PF12831.2 EXF76943.1 - 0.038 13.0 0.8 0.059 12.4 0.5 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EXF76943.1 - 0.07 12.1 0.1 1.3 7.9 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EXF76943.1 - 0.082 12.6 0.1 8.5 6.1 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding PC_rep PF01851.17 EXF76943.1 - 0.13 12.5 0.1 3.2 8.1 0.0 3.1 3 1 0 3 3 2 0 Proteasome/cyclosome repeat ApbA PF02558.11 EXF76943.1 - 0.17 11.3 0.1 0.3 10.5 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_1 PF00667.15 EXF76944.1 - 3.1e-37 128.1 0.0 5e-37 127.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EXF76944.1 - 1.5e-25 89.8 0.1 3.3e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EXF76944.1 - 3.3e-19 69.4 0.1 1.5e-18 67.3 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain p450 PF00067.17 EXF76945.1 - 7.4e-67 225.8 0.0 9.5e-67 225.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 EXF76946.1 - 7.8e-107 357.6 20.7 9.1e-107 357.4 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF76946.1 - 1.4e-27 96.3 58.6 5.9e-18 64.6 19.2 2.6 1 1 2 3 3 3 3 Major Facilitator Superfamily TRI12 PF06609.8 EXF76946.1 - 1.3e-05 23.5 1.4 1.3e-05 23.5 1.0 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) UNC-93 PF05978.11 EXF76946.1 - 8e-05 22.1 4.1 8e-05 22.1 2.8 2.7 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 DUF4131 PF13567.1 EXF76946.1 - 8.3 5.7 17.1 0.8 9.0 0.0 3.8 4 1 0 4 4 4 0 Domain of unknown function (DUF4131) DUF3835 PF12927.2 EXF76947.1 - 0.041 14.8 0.3 0.12 13.3 0.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3835) Sugar_tr PF00083.19 EXF76948.1 - 1.9e-55 188.2 27.2 2.2e-55 188.0 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF76948.1 - 1.6e-16 59.9 45.0 1.2e-15 57.1 16.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.11 EXF76948.1 - 0.00067 18.5 1.5 0.00067 18.5 1.1 2.3 2 0 0 2 2 2 1 Nucleoside H+ symporter DUF872 PF05915.7 EXF76948.1 - 0.0032 17.3 0.1 0.64 9.8 0.0 2.9 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF872) DUF4387 PF14330.1 EXF76949.1 - 2.3e-29 101.6 0.0 4.7e-29 100.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 EXF76949.1 - 2.1e-10 39.6 0.0 8.1e-10 37.6 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1446) Flavodoxin_3 PF12641.2 EXF76949.1 - 0.097 12.0 0.0 0.22 10.9 0.0 1.6 2 0 0 2 2 2 0 Flavodoxin domain Glyco_hydro_43 PF04616.9 EXF76950.1 - 5.1e-32 111.0 0.0 6.3e-32 110.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 p450 PF00067.17 EXF76951.1 - 1.1e-07 30.8 0.0 2.1e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Aa_trans PF01490.13 EXF76952.1 - 1.3e-28 99.6 34.2 2.4e-28 98.7 23.7 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Shisa PF13908.1 EXF76952.1 - 0.67 10.1 3.5 11 6.1 0.1 2.9 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Methyltransf_16 PF10294.4 EXF76953.1 - 4.9e-06 26.1 0.0 7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EXF76953.1 - 0.0032 16.6 0.0 0.0048 16.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 EXF76954.1 - 3.6e-14 52.8 0.0 5.8e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF76954.1 - 6e-09 36.2 0.0 1.3e-08 35.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF76954.1 - 7.6e-07 29.4 0.0 7.1e-06 26.3 0.0 2.6 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF76954.1 - 6.5e-06 25.8 0.0 5.3e-05 22.8 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF76954.1 - 2.1e-05 24.8 0.0 0.00017 22.0 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF76954.1 - 0.00056 19.0 0.0 0.002 17.2 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EXF76954.1 - 0.01 16.4 0.0 0.053 14.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EXF76954.1 - 0.046 13.3 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_26 PF13659.1 EXF76954.1 - 0.12 12.4 0.0 0.41 10.7 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Ribosomal_L22 PF00237.14 EXF76955.1 - 3.7e-34 116.8 0.0 5.4e-34 116.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF3455 PF11937.3 EXF76957.1 - 3.6e-42 144.3 0.0 4.8e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) CASP_C PF08172.7 EXF76958.1 - 1.4e-88 296.0 0.0 1.4e-88 296.0 0.0 3.9 2 1 1 3 3 2 1 CASP C terminal ADIP PF11559.3 EXF76958.1 - 0.0057 16.5 6.5 0.0057 16.5 4.5 6.7 4 2 3 7 7 7 3 Afadin- and alpha -actinin-Binding bZIP_2 PF07716.10 EXF76958.1 - 0.0098 15.6 1.4 0.0098 15.6 1.0 7.5 8 1 0 8 8 8 3 Basic region leucine zipper Filament PF00038.16 EXF76958.1 - 0.012 15.1 46.2 2.7 7.3 0.1 3.8 3 1 1 4 4 4 0 Intermediate filament protein SlyX PF04102.7 EXF76958.1 - 0.024 15.0 0.0 0.024 15.0 0.0 6.1 6 0 0 6 6 6 0 SlyX DUF4164 PF13747.1 EXF76958.1 - 0.035 14.2 0.6 0.035 14.2 0.4 5.9 5 1 0 5 5 5 0 Domain of unknown function (DUF4164) Striatin PF08232.7 EXF76958.1 - 0.068 13.4 0.0 0.068 13.4 0.0 5.1 2 1 2 4 4 3 0 Striatin family DUF972 PF06156.8 EXF76958.1 - 0.49 10.7 40.8 0.82 10.0 0.0 6.2 4 2 3 7 7 7 0 Protein of unknown function (DUF972) Metal_resist PF13801.1 EXF76958.1 - 1.4 8.9 0.0 1.4 8.9 0.0 3.6 4 0 0 4 4 3 0 Heavy-metal resistance Tropomyosin_1 PF12718.2 EXF76958.1 - 4.5 7.0 56.1 1 9.1 5.7 5.4 2 1 3 5 5 5 0 Tropomyosin like Reo_sigmaC PF04582.7 EXF76958.1 - 9 5.3 34.1 0.26 10.4 2.4 4.5 3 1 1 5 5 5 0 Reovirus sigma C capsid protein Vps39_2 PF10367.4 EXF76959.1 - 1.5e-07 31.5 0.0 4.2e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 EXF76959.1 - 0.19 11.7 0.0 0.73 9.8 0.0 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 HEAT PF02985.17 EXF76960.1 - 1.7e-28 96.0 12.0 3e-05 23.7 0.0 11.1 12 0 0 12 12 10 6 HEAT repeat HEAT_2 PF13646.1 EXF76960.1 - 6.1e-27 93.7 0.3 3.2e-07 30.5 0.0 8.3 3 3 6 9 9 9 8 HEAT repeats HEAT_EZ PF13513.1 EXF76960.1 - 2.4e-25 88.2 17.0 6.1e-12 45.6 0.0 12.0 9 2 7 16 16 15 5 HEAT-like repeat Cnd1 PF12717.2 EXF76960.1 - 7.3e-12 45.4 1.1 0.0016 18.3 0.0 5.8 3 3 1 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EXF76960.1 - 2.1e-11 44.0 0.0 0.00041 20.6 0.0 6.3 5 2 1 6 6 6 1 Vacuolar 14 Fab1-binding region MMS19_C PF12460.3 EXF76960.1 - 2.9e-11 42.7 1.4 0.0015 17.3 0.0 4.9 5 0 0 5 5 5 3 RNAPII transcription regulator C-terminal CLASP_N PF12348.3 EXF76960.1 - 7e-08 32.0 0.0 1.6 8.0 0.0 6.6 5 2 1 6 6 6 1 CLASP N terminal IBN_N PF03810.14 EXF76960.1 - 2.7e-06 27.1 0.6 0.00025 20.8 0.1 4.5 3 1 0 3 3 3 1 Importin-beta N-terminal domain HEAT_PBS PF03130.11 EXF76960.1 - 0.00044 20.4 5.1 17 6.1 0.0 6.0 6 0 0 6 6 4 0 PBS lyase HEAT-like repeat DUF3437 PF11919.3 EXF76960.1 - 0.0023 17.6 0.4 0.5 10.1 0.0 3.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) Arm PF00514.18 EXF76960.1 - 0.0069 16.1 7.6 4.8 7.1 0.0 6.0 6 1 0 6 6 6 2 Armadillo/beta-catenin-like repeat RIX1 PF08167.7 EXF76960.1 - 0.096 12.3 0.0 4.9 6.7 0.0 3.7 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis XPC-binding PF09280.6 EXF76960.1 - 0.32 10.5 6.0 10 5.7 0.1 4.6 4 0 0 4 4 4 0 XPC-binding domain chaperone_DMP PF10448.4 EXF76961.1 - 0.04 13.7 0.0 0.057 13.3 0.0 1.4 1 1 0 1 1 1 0 20S proteasome chaperone GCD14 PF08704.5 EXF76962.1 - 0.058 12.8 0.0 2.9 7.2 0.0 2.4 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Hepatitis_core PF00906.15 EXF76965.1 - 8.4 5.9 6.4 7.3 6.1 0.0 2.1 2 0 0 2 2 2 0 Hepatitis core antigen Peptidase_C12 PF01088.16 EXF76966.1 - 4e-70 235.3 0.0 5e-70 235.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Xan_ur_permease PF00860.15 EXF76967.1 - 2.5e-26 92.1 26.7 1.8e-25 89.2 16.1 3.0 2 1 0 2 2 2 1 Permease family SCIMP PF15050.1 EXF76969.1 - 0.013 15.3 0.0 0.015 15.1 0.0 1.0 1 0 0 1 1 1 0 SCIMP protein DUF4655 PF15548.1 EXF76969.1 - 0.081 11.8 0.1 0.086 11.7 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4655) DUF2749 PF10907.3 EXF76969.1 - 0.13 12.1 0.0 0.21 11.4 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2749) 7tm_2 PF00002.19 EXF76970.1 - 3.3e-12 46.0 5.1 3.3e-12 46.0 3.5 1.5 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 EXF76970.1 - 4e-11 42.3 5.1 4e-11 42.3 3.6 1.9 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 EXF76970.1 - 1.4e-06 27.9 7.0 3.2e-06 26.8 4.8 1.6 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7TM_GPCR_Srsx PF10320.4 EXF76970.1 - 0.0031 16.7 2.9 0.0031 16.7 2.0 1.8 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srsx Fibrillarin PF01269.12 EXF76972.1 - 2.4e-104 347.2 0.0 3e-104 346.9 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.5 EXF76972.1 - 0.00011 21.7 0.1 0.00024 20.7 0.1 1.5 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EXF76972.1 - 0.16 11.5 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain TPT PF03151.11 EXF76974.1 - 9.1e-21 74.1 9.3 9.1e-21 74.1 6.4 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EXF76974.1 - 1.8e-05 23.8 18.9 5.9e-05 22.1 13.1 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EXF76974.1 - 0.02 14.9 29.0 0.044 13.8 7.3 2.9 2 2 1 3 3 3 0 EamA-like transporter family APH PF01636.18 EXF76975.1 - 2.2e-05 24.2 0.2 0.00012 21.8 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Steroid_dh PF02544.11 EXF76976.1 - 9.4e-16 57.9 0.9 2e-15 56.8 0.6 1.6 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EXF76976.1 - 0.00031 20.1 0.8 0.00078 18.8 0.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EXF76976.1 - 0.029 14.4 1.6 0.072 13.2 0.1 2.4 2 0 0 2 2 2 0 Phospholipid methyltransferase DUF2085 PF09858.4 EXF76976.1 - 0.047 13.7 0.5 13 5.8 0.1 3.2 3 0 0 3 3 3 0 Predicted membrane protein (DUF2085) 2OG-FeII_Oxy_2 PF13532.1 EXF76977.1 - 0.00089 19.1 0.1 0.017 14.9 0.1 2.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EXF76977.1 - 0.034 14.4 0.0 0.096 12.9 0.0 1.9 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.2 EXF76978.1 - 4.8e-26 90.9 0.0 1e-16 61.0 0.1 2.4 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EXF76978.1 - 1.8e-19 68.4 5.2 5e-08 32.3 0.1 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EXF76978.1 - 1.9e-15 56.8 1.3 4.1e-08 33.5 0.1 4.5 2 2 4 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF76978.1 - 1.6e-13 50.4 7.0 4.4e-07 29.9 0.1 4.1 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF76978.1 - 3.6e-13 48.3 0.1 8.7e-05 22.3 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat MMR_HSR1 PF01926.18 EXF76979.1 - 2.2e-18 66.2 0.1 1.3e-17 63.8 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 EXF76979.1 - 1.3e-16 60.2 0.0 3.1e-16 58.9 0.0 1.7 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 EXF76979.1 - 5.9e-10 38.6 0.1 3.5e-09 36.1 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EXF76979.1 - 5e-05 23.1 0.2 0.014 15.2 0.0 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 EXF76979.1 - 5.1e-05 22.7 0.4 0.56 9.6 0.0 3.8 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain ArgK PF03308.11 EXF76979.1 - 0.00033 19.5 0.4 0.022 13.5 0.1 2.2 2 0 0 2 2 2 1 ArgK protein Miro PF08477.8 EXF76979.1 - 0.005 17.3 0.0 0.084 13.3 0.0 2.6 3 0 0 3 3 3 1 Miro-like protein AIG1 PF04548.11 EXF76979.1 - 0.018 14.1 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 AIG1 family Arf PF00025.16 EXF76979.1 - 0.061 12.5 0.3 11 5.1 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family HTH_Tnp_Tc5 PF03221.11 EXF76980.1 - 3.8e-11 42.6 0.0 1.1e-10 41.1 0.0 1.8 2 0 0 2 2 2 1 Tc5 transposase DNA-binding domain CENP-B_N PF04218.8 EXF76980.1 - 5.2e-06 25.7 0.0 8.8e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain MarR PF01047.17 EXF76980.1 - 0.00076 19.1 0.0 0.023 14.4 0.0 2.5 2 0 0 2 2 2 1 MarR family HTH_Crp_2 PF13545.1 EXF76980.1 - 0.016 15.0 0.0 0.051 13.3 0.0 1.8 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain HTH_Tnp_4 PF13613.1 EXF76980.1 - 0.019 14.5 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_23 PF13384.1 EXF76980.1 - 0.063 12.9 0.0 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 Homeodomain-like domain SMN PF06003.7 EXF76980.1 - 0.076 12.1 9.6 2.8 6.9 5.2 2.4 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) PXA PF02194.10 EXF76981.1 - 8.8e-41 139.5 0.7 1.8e-40 138.4 0.3 1.6 2 0 0 2 2 2 1 PXA domain zf-Mss51 PF13824.1 EXF76982.1 - 6.6e-26 89.9 5.9 1.3e-25 88.9 4.1 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 CPSF_A PF03178.10 EXF76983.1 - 2.2e-100 335.9 0.0 8.2e-100 333.9 0.0 2.0 3 0 0 3 3 3 1 CPSF A subunit region MMS1_N PF10433.4 EXF76983.1 - 1.7e-68 231.0 0.0 2.9e-68 230.2 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term UBA_4 PF14555.1 EXF76984.1 - 0.0014 18.1 0.0 0.0026 17.2 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain DUF605 PF04652.11 EXF76984.1 - 2.1 7.6 8.7 2.8 7.2 6.0 1.1 1 0 0 1 1 1 0 Vta1 like DZR PF12773.2 EXF76984.1 - 2.9 7.7 11.9 0.1 12.3 1.8 1.8 1 1 1 2 2 2 0 Double zinc ribbon TraG_N PF07916.6 EXF76986.1 - 0.97 7.8 5.0 1.4 7.2 3.5 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Glyco_hydro_43 PF04616.9 EXF76987.1 - 1e-33 116.6 0.9 1.3e-33 116.3 0.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Ribosomal_60s PF00428.14 EXF76988.1 - 0.16 12.3 2.0 0.33 11.3 1.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein Fungal_trans PF04082.13 EXF76990.1 - 5.5e-21 74.6 0.3 9.5e-21 73.8 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF76990.1 - 5.9e-08 32.5 9.1 1.4e-07 31.3 6.3 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EXF76991.1 - 5.9e-106 354.7 24.1 6.7e-106 354.5 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF76991.1 - 2.1e-25 89.2 44.5 2.5e-19 69.2 7.2 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily DUF3671 PF12420.3 EXF76991.1 - 0.8 9.7 2.3 7.1 6.6 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function Fungal_trans_2 PF11951.3 EXF76992.1 - 1.1e-21 76.9 0.0 1.4e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DHDPS PF00701.17 EXF76993.1 - 1.1e-43 148.9 0.0 1.3e-43 148.6 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MIP-T3 PF10243.4 EXF76994.1 - 0.012 14.1 8.8 0.013 14.0 6.1 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 ROKNT PF08067.6 EXF76994.1 - 0.7 9.7 30.7 15 5.5 0.5 8.3 1 1 5 6 6 6 0 ROKNT (NUC014) domain Peptidase_M20 PF01546.23 EXF76994.1 - 1.8 8.0 6.7 16 4.9 0.1 3.4 1 1 1 2 2 2 0 Peptidase family M20/M25/M40 DUF3328 PF11807.3 EXF76995.1 - 1.7e-40 139.0 4.6 1.8e-29 103.0 0.1 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF3328) IFP_35_N PF07334.8 EXF76996.1 - 0.0073 16.2 1.1 0.015 15.2 0.8 1.5 1 0 0 1 1 1 1 Interferon-induced 35 kDa protein (IFP 35) N-terminus SET PF00856.23 EXF76997.1 - 1e-12 48.6 0.0 2.5e-12 47.4 0.0 1.7 1 1 0 1 1 1 1 SET domain HET PF06985.6 EXF76998.1 - 1.8e-28 99.4 0.1 5.4e-28 97.8 0.1 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.19 EXF76999.1 - 1.6e-96 323.6 32.5 2e-96 323.3 22.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF76999.1 - 4.2e-22 78.3 32.6 4.2e-22 78.3 22.6 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily Tmemb_18A PF09771.4 EXF76999.1 - 0.062 13.2 0.2 0.33 10.9 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 188 AA_permease PF00324.16 EXF77000.1 - 4.5e-97 325.3 44.7 5.5e-97 325.0 31.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF77000.1 - 8.5e-28 97.0 45.8 1e-27 96.7 31.8 1.1 1 0 0 1 1 1 1 Amino acid permease NACHT PF05729.7 EXF77001.1 - 2e-09 37.2 0.0 4.3e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PNP_UDP_1 PF01048.15 EXF77001.1 - 1.3e-08 34.0 0.0 6.2e-08 31.8 0.0 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily AAA_16 PF13191.1 EXF77001.1 - 2.7e-07 30.7 0.7 7.5e-07 29.3 0.2 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EXF77001.1 - 0.00094 19.3 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EXF77001.1 - 0.021 15.0 2.7 0.087 13.0 0.1 3.2 3 2 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EXF77001.1 - 0.045 13.4 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain APS_kinase PF01583.15 EXF77001.1 - 0.073 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase RNA_helicase PF00910.17 EXF77001.1 - 0.12 12.5 0.0 0.5 10.5 0.0 2.1 1 0 0 1 1 1 0 RNA helicase KAP_NTPase PF07693.9 EXF77001.1 - 0.13 11.2 1.0 0.22 10.4 0.7 1.3 1 1 0 1 1 1 0 KAP family P-loop domain DUF4658 PF15555.1 EXF77003.1 - 0.073 12.9 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4658) Flavi_NS2A PF01005.14 EXF77003.1 - 0.11 11.7 0.0 0.13 11.4 0.0 1.1 1 0 0 1 1 1 0 Flavivirus non-structural protein NS2A LDB19 PF13002.2 EXF77004.1 - 1.7e-34 118.9 0.3 2.9e-34 118.2 0.2 1.2 1 0 0 1 1 1 1 Arrestin_N terminal like Arrestin_N PF00339.24 EXF77004.1 - 1.2e-06 28.3 0.1 3.4e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain p450 PF00067.17 EXF77005.1 - 1.4e-24 86.4 0.0 1.6e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_16 PF00722.16 EXF77007.1 - 2.7e-15 56.1 0.1 4.1e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 EXF77007.1 - 1.3e-06 26.8 0.5 0.0032 15.6 0.0 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) WBS_methylT PF12589.3 EXF77008.1 - 0.62 10.5 4.4 1 9.8 3.0 1.4 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome MFS_1 PF07690.11 EXF77009.1 - 2.7e-29 102.0 27.2 4.1e-29 101.4 18.9 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Ribonuc_L-PSP PF01042.16 EXF77010.1 - 1.1e-16 60.6 0.0 1.4e-16 60.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Pectate_lyase PF03211.8 EXF77013.1 - 3.7e-65 219.3 3.7 5.8e-65 218.7 2.6 1.2 1 0 0 1 1 1 1 Pectate lyase NmrA PF05368.8 EXF77015.1 - 4.1e-14 52.4 0.0 5.3e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family TPR_12 PF13424.1 EXF77016.1 - 2e-14 53.2 27.0 3.4e-05 23.7 0.1 7.2 6 1 0 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.1 EXF77016.1 - 6.1e-10 38.7 15.7 0.093 12.6 0.7 7.6 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_11 PF13414.1 EXF77016.1 - 2.5e-07 30.2 14.3 0.0019 17.8 0.1 5.5 7 0 0 7 7 7 2 TPR repeat TPR_2 PF07719.12 EXF77016.1 - 9e-05 22.1 30.9 2.8 8.0 0.8 8.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.1 EXF77016.1 - 0.0042 17.5 20.6 32 5.5 0.0 8.3 7 1 1 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.1 EXF77016.1 - 0.016 15.6 10.3 4.1 8.0 1.0 6.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_1 PF00515.23 EXF77016.1 - 0.062 12.9 20.9 2.7 7.7 0.2 7.3 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_7 PF13176.1 EXF77016.1 - 0.086 12.6 19.2 7.8 6.5 0.4 7.8 8 0 0 8 8 8 0 Tetratricopeptide repeat ABC2_membrane PF01061.19 EXF77017.1 - 4.4e-85 284.1 61.1 6.1e-45 152.9 15.2 3.5 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 EXF77017.1 - 1.7e-39 133.5 9.0 4.1e-35 119.5 0.0 3.5 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 EXF77017.1 - 4.5e-38 130.6 0.0 2.1e-17 63.6 0.0 3.4 4 0 0 4 4 3 2 ABC transporter ABC_trans_N PF14510.1 EXF77017.1 - 1.4e-18 66.7 0.0 3.6e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 EXF77017.1 - 3.1e-07 30.3 0.1 0.0094 15.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EXF77017.1 - 3.9e-07 29.6 0.0 0.00015 21.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EXF77017.1 - 1.1e-05 24.7 0.0 0.0015 17.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC2_membrane_3 PF12698.2 EXF77017.1 - 1.9e-05 23.9 47.2 0.00042 19.4 11.2 3.1 2 1 1 3 3 3 2 ABC-2 family transporter protein AAA_16 PF13191.1 EXF77017.1 - 3e-05 24.0 0.0 0.029 14.3 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EXF77017.1 - 8.2e-05 22.0 1.2 0.023 14.1 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EXF77017.1 - 0.00021 21.5 0.0 0.041 14.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EXF77017.1 - 0.00022 22.0 0.0 0.082 13.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EXF77017.1 - 0.00034 20.0 0.9 0.016 14.6 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 EXF77017.1 - 0.00067 18.9 0.0 0.17 11.0 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EXF77017.1 - 0.00097 19.2 0.1 2.2 8.4 0.0 3.2 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 EXF77017.1 - 0.012 15.2 0.5 1.8 8.1 0.0 2.6 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 EXF77017.1 - 0.015 15.0 2.8 3.6 7.4 0.0 2.9 3 0 0 3 3 2 0 Part of AAA domain AAA PF00004.24 EXF77017.1 - 0.03 14.5 0.0 11 6.2 0.0 2.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 EXF77017.1 - 0.038 13.9 0.1 0.97 9.3 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_28 PF13521.1 EXF77017.1 - 0.054 13.4 0.5 4.1 7.3 0.2 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EXF77017.1 - 0.076 12.5 0.2 5.5 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EXF77017.1 - 0.09 12.1 0.5 4.6 6.5 0.0 2.6 2 0 0 2 2 2 0 AAA-like domain p450 PF00067.17 EXF77019.1 - 1.6e-65 221.4 0.0 2.7e-65 220.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 WG_beta_rep PF14903.1 EXF77019.1 - 0.00035 20.6 0.1 0.0017 18.4 0.1 2.1 2 0 0 2 2 2 1 WG containing repeat fn3 PF00041.16 EXF77020.1 - 0.00026 21.0 1.5 0.0059 16.7 0.3 2.7 2 0 0 2 2 2 1 Fibronectin type III domain Dynein_heavy PF03028.10 EXF77020.1 - 0.27 9.2 0.0 0.37 8.7 0.0 1.1 1 0 0 1 1 1 0 Dynein heavy chain and region D6 of dynein motor TrbC_Ftype PF09673.5 EXF77021.1 - 0.26 10.9 2.5 1.8 8.1 0.4 2.9 1 1 1 2 2 2 0 Type-F conjugative transfer system pilin assembly protein HMG_box PF00505.14 EXF77023.1 - 3.6e-17 62.3 1.0 5.4e-17 61.8 0.1 1.8 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EXF77023.1 - 9.7e-13 48.2 0.1 2.5e-12 46.9 0.1 1.7 1 0 0 1 1 1 1 HMG-box domain SAM_1 PF00536.25 EXF77023.1 - 2.8e-11 43.3 0.0 4.8e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EXF77023.1 - 5.7e-09 35.6 0.0 1.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF822 PF05687.8 EXF77023.1 - 1.3 9.3 7.5 0.69 10.2 2.6 2.3 1 1 1 2 2 2 0 Plant protein of unknown function (DUF822) SH3_1 PF00018.23 EXF77025.1 - 1.5e-09 37.1 0.0 2.5e-09 36.3 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EXF77025.1 - 8.8e-09 34.8 0.1 1.8e-08 33.7 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EXF77025.1 - 4.2e-06 26.1 0.0 1.8e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain NAD_binding_1 PF00175.16 EXF77026.1 - 6.7e-31 107.0 0.0 1.4e-30 106.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EXF77026.1 - 7.4e-21 74.1 0.0 1.3e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EXF77026.1 - 2.4e-09 37.2 0.0 0.0001 22.2 0.0 2.3 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EXF77026.1 - 0.0036 17.2 0.0 0.0066 16.4 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain Peptidase_M28 PF04389.12 EXF77027.1 - 1.8e-15 57.1 0.0 3.2e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 TFR_dimer PF04253.10 EXF77027.1 - 6.1e-15 54.9 0.0 1.1e-14 54.0 0.0 1.6 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain PA PF02225.17 EXF77027.1 - 1.6e-07 30.9 0.4 1e-06 28.3 0.1 2.3 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 EXF77027.1 - 0.0033 16.9 0.0 0.0063 16.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 MFS_1 PF07690.11 EXF77028.1 - 4.2e-39 134.2 27.1 4.2e-27 94.7 3.1 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF77028.1 - 0.00058 18.1 0.2 0.00058 18.1 0.1 1.5 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) IMPDH PF00478.20 EXF77029.1 - 2.3e-130 434.6 1.1 2.8e-130 434.3 0.8 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EXF77029.1 - 1.3e-15 56.8 0.1 4.7e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 EXF77029.1 - 1.3e-09 37.7 1.7 0.0011 18.2 0.0 2.2 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 EXF77029.1 - 5.5e-09 35.3 0.4 9.7e-07 27.9 0.4 2.3 2 0 0 2 2 2 2 FMN-dependent dehydrogenase His_biosynth PF00977.16 EXF77029.1 - 0.00018 20.8 3.5 0.014 14.6 0.2 2.9 2 1 1 3 3 3 2 Histidine biosynthesis protein ThiG PF05690.9 EXF77029.1 - 0.04 12.9 1.2 0.12 11.3 0.2 2.1 1 1 2 3 3 3 0 Thiazole biosynthesis protein ThiG RasGAP_C PF03836.10 EXF77030.1 - 5e-50 168.8 2.9 1.9e-49 166.9 2.0 2.1 1 0 0 1 1 1 1 RasGAP C-terminus RasGAP PF00616.14 EXF77030.1 - 7.2e-42 143.2 0.0 1.9e-41 141.8 0.0 1.8 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase IQ PF00612.22 EXF77030.1 - 1.3e-19 67.8 27.6 0.0012 18.3 0.1 14.5 14 0 0 14 14 14 6 IQ calmodulin-binding motif CH PF00307.26 EXF77030.1 - 4.7e-10 39.4 0.0 1.3e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain Sulfatase PF00884.18 EXF77031.1 - 2.3e-56 191.2 0.0 2.9e-56 190.8 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Choline_sulf_C PF12411.3 EXF77031.1 - 1.8e-22 78.8 1.2 1.8e-22 78.8 0.8 2.4 2 1 1 3 3 3 1 Choline sulfatase enzyme C terminal Phosphodiest PF01663.17 EXF77031.1 - 2.5e-10 40.2 0.1 2.5e-09 36.9 0.0 2.3 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EXF77031.1 - 0.091 11.1 0.0 0.12 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) Metalloenzyme PF01676.13 EXF77031.1 - 0.1 11.9 0.0 2 7.7 0.0 2.3 2 0 0 2 2 2 0 Metalloenzyme superfamily Med8 PF10232.4 EXF77032.1 - 1.3e-25 90.2 3.2 4e-24 85.3 0.2 2.1 2 0 0 2 2 2 2 Mediator of RNA polymerase II transcription complex subunit 8 Nop14 PF04147.7 EXF77032.1 - 0.28 9.0 4.6 0.45 8.3 3.2 1.3 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 EXF77032.1 - 0.8 8.3 5.2 1.1 7.9 3.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 EXF77032.1 - 1.8 8.0 8.5 3.6 7.1 5.9 1.4 1 0 0 1 1 1 0 Nucleoplasmin HET PF06985.6 EXF77033.1 - 2.9e-23 82.5 0.0 4.6e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF4188 PF13826.1 EXF77034.1 - 4.2e-33 113.9 0.1 6.1e-33 113.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) Dehydratase_hem PF13816.1 EXF77034.1 - 0.0045 16.0 0.1 0.094 11.7 0.0 1.9 1 1 1 2 2 2 2 Haem-containing dehydratase MFS_1 PF07690.11 EXF77035.1 - 1.9e-29 102.4 24.4 1.3e-24 86.5 4.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BLUF PF04940.7 EXF77035.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Sensors of blue-light using FAD 2OG-FeII_Oxy PF03171.15 EXF77036.1 - 1.3e-12 47.8 0.1 3.6e-12 46.4 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EXF77036.1 - 6.1e-11 42.8 0.0 1.9e-10 41.2 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal NAD_binding_2 PF03446.10 EXF77037.1 - 7.1e-26 90.9 0.9 1.1e-25 90.3 0.6 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EXF77037.1 - 9.5e-09 35.3 0.0 2e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EXF77037.1 - 1.3e-05 25.5 0.1 7.7e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EXF77037.1 - 0.00018 21.6 0.0 0.00033 20.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EXF77037.1 - 0.007 15.5 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMN_red PF03358.10 EXF77037.1 - 0.059 12.8 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 NADPH-dependent FMN reductase IlvN PF07991.7 EXF77037.1 - 0.087 12.1 0.1 0.54 9.5 0.0 2.0 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain Fungal_trans PF04082.13 EXF77038.1 - 5.9e-22 77.7 0.6 9.1e-22 77.1 0.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain GST_C PF00043.20 EXF77038.1 - 1.1e-11 44.5 0.0 3.4e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EXF77038.1 - 1.7e-08 34.2 0.1 6.5e-08 32.3 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EXF77038.1 - 5.6e-06 26.4 0.0 2.5e-05 24.3 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EXF77038.1 - 1.7e-05 24.9 0.0 5.5e-05 23.3 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EXF77038.1 - 3.1e-05 24.3 0.0 0.00012 22.4 0.0 2.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DIOX_N PF14226.1 EXF77039.1 - 1.8e-13 51.0 0.0 5e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EXF77039.1 - 6.4e-08 32.8 0.0 1.4e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 EXF77040.1 - 0.0016 17.3 0.0 0.0031 16.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain PhyH PF05721.8 EXF77041.1 - 2.9e-13 50.3 0.0 4.9e-13 49.5 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 EXF77041.1 - 0.075 13.3 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Sugar_tr PF00083.19 EXF77042.1 - 5.2e-107 358.2 28.3 5.9e-107 358.0 19.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF77042.1 - 3.8e-16 58.7 30.2 3.8e-16 58.7 20.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily GST_C PF00043.20 EXF77043.1 - 3.9e-07 29.9 0.1 7.6e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EXF77043.1 - 9.3e-07 28.9 0.0 1.8e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EXF77043.1 - 1.9e-06 27.7 0.0 2e-05 24.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EXF77043.1 - 3.5e-06 27.0 0.0 3.6e-05 23.8 0.0 2.5 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EXF77043.1 - 2.4e-05 24.7 0.1 3.7e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EXF77043.1 - 0.061 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glyco_transf_20 PF00982.16 EXF77045.1 - 1.7e-145 485.1 0.0 2.5e-145 484.5 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EXF77045.1 - 8.7e-76 253.9 0.0 1.6e-75 253.0 0.0 1.5 1 0 0 1 1 1 1 Trehalose-phosphatase Apc15p PF05841.6 EXF77045.1 - 0.65 10.7 6.9 1.2 9.8 4.8 1.5 1 0 0 1 1 1 0 Apc15p protein Peptidase_S8 PF00082.17 EXF77046.1 - 1.1e-46 159.2 3.1 1.8e-46 158.5 2.2 1.4 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EXF77046.1 - 0.0044 17.5 0.0 0.011 16.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 DUF1034 PF06280.7 EXF77046.1 - 0.045 14.1 0.0 0.17 12.3 0.0 2.0 2 0 0 2 2 2 0 Fn3-like domain (DUF1034) BTB PF00651.26 EXF77047.1 - 2.6e-12 46.7 0.1 5.9e-12 45.5 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain Glyco_hydro_3 PF00933.16 EXF77048.1 - 1.9e-51 174.8 0.1 2.8e-51 174.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF77048.1 - 8.2e-47 159.6 0.0 1.7e-46 158.5 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF77048.1 - 6.4e-24 83.6 0.1 1.2e-23 82.7 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain ABC_membrane PF00664.18 EXF77049.1 - 2e-36 125.8 14.7 2.7e-36 125.3 10.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EXF77049.1 - 2.5e-33 115.2 0.0 5.4e-33 114.1 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EXF77049.1 - 3.4e-07 30.4 0.1 2.6e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 EXF77049.1 - 2.7e-05 24.2 0.0 0.16 11.9 0.0 2.4 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 EXF77049.1 - 6.5e-05 22.2 0.0 0.013 14.7 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_14 PF13173.1 EXF77049.1 - 0.00028 20.7 0.0 0.002 18.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EXF77049.1 - 0.00034 20.7 0.0 0.0022 18.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EXF77049.1 - 0.00034 20.1 0.2 0.0029 17.1 0.0 2.1 1 1 1 2 2 2 1 AAA-like domain AAA_17 PF13207.1 EXF77049.1 - 0.00067 20.4 0.0 0.0015 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EXF77049.1 - 0.00088 18.4 0.0 0.0016 17.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EXF77049.1 - 0.0053 16.2 0.0 0.015 14.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.1 EXF77049.1 - 0.011 15.6 0.0 0.029 14.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EXF77049.1 - 0.012 15.3 0.0 0.03 14.0 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EXF77049.1 - 0.017 15.0 0.0 0.053 13.4 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_25 PF13481.1 EXF77049.1 - 0.018 14.4 0.0 0.043 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EXF77049.1 - 0.026 14.7 0.0 0.14 12.3 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EXF77049.1 - 0.031 14.2 0.0 0.073 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 EXF77049.1 - 0.035 14.0 0.3 0.43 10.5 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Miro PF08477.8 EXF77049.1 - 0.04 14.4 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein Arch_ATPase PF01637.13 EXF77049.1 - 0.04 13.5 0.0 0.094 12.3 0.0 1.7 1 1 0 1 1 1 0 Archaeal ATPase AAA_18 PF13238.1 EXF77049.1 - 0.047 13.9 0.0 0.14 12.4 0.0 1.8 2 0 0 2 2 1 0 AAA domain Septin PF00735.13 EXF77049.1 - 0.067 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Septin NACHT PF05729.7 EXF77049.1 - 0.073 12.7 0.3 0.21 11.2 0.0 1.9 3 0 0 3 3 2 0 NACHT domain CorA PF01544.13 EXF77050.1 - 1.7e-13 50.2 1.1 3.6e-13 49.2 0.1 2.0 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein 3Beta_HSD PF01073.14 EXF77051.1 - 8.7e-09 34.4 0.0 1.3e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EXF77051.1 - 1.7e-08 34.1 0.0 2.8e-08 33.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF77051.1 - 4.8e-07 29.9 0.0 1.5e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EXF77051.1 - 1.4e-05 24.4 0.1 2.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EXF77051.1 - 0.00089 18.2 0.0 0.76 8.6 0.0 2.3 2 1 0 2 2 2 2 Male sterility protein adh_short PF00106.20 EXF77051.1 - 0.0027 17.6 0.0 0.01 15.7 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase p450 PF00067.17 EXF77052.1 - 1.6e-23 82.9 0.0 2e-22 79.3 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 DUF4646 PF15496.1 EXF77054.1 - 0.00091 19.2 0.0 0.043 13.8 0.0 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4646) Med13_C PF06333.7 EXF77054.1 - 0.47 8.9 2.8 0.76 8.2 1.9 1.2 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal Sugar_tr PF00083.19 EXF77055.1 - 1.8e-70 237.7 15.8 2.2e-70 237.4 11.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF77055.1 - 4.6e-29 101.2 18.2 6.2e-29 100.8 12.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EXF77055.1 - 1.7e-08 33.1 2.0 2.5e-08 32.5 1.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MMPL PF03176.10 EXF77055.1 - 0.037 12.7 2.6 0.29 9.8 1.2 2.3 2 0 0 2 2 2 0 MMPL family DUF1228 PF06779.9 EXF77055.1 - 0.7 9.9 6.7 0.12 12.3 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) DUF1479 PF07350.7 EXF77056.1 - 5.6e-117 390.7 0.0 6.6e-117 390.4 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) Fungal_trans PF04082.13 EXF77057.1 - 1.3e-09 37.3 0.2 1.9e-09 36.8 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Amidohydro_1 PF01979.15 EXF77058.1 - 1.2e-35 123.7 0.0 1.5e-35 123.4 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EXF77058.1 - 1e-10 41.4 0.2 1.8e-06 27.4 0.0 3.2 2 1 1 3 3 3 3 Amidohydrolase family Amidohydro_5 PF13594.1 EXF77058.1 - 3.8e-07 29.8 0.0 8.8e-07 28.6 0.0 1.7 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EXF77058.1 - 5.1e-07 29.9 0.1 0.0089 16.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase YlbD_coat PF14071.1 EXF77058.1 - 0.022 14.7 0.0 0.86 9.6 0.0 2.3 2 0 0 2 2 2 0 Putative coat protein A_deaminase PF00962.17 EXF77058.1 - 0.023 13.6 0.0 0.042 12.7 0.0 1.4 1 0 0 1 1 1 0 Adenosine/AMP deaminase Abhydrolase_6 PF12697.2 EXF77059.1 - 3.7e-35 121.8 0.2 4.4e-35 121.6 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF77059.1 - 3.4e-25 88.9 0.0 4.6e-25 88.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF77059.1 - 6.9e-18 64.7 0.0 1.1e-16 60.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF77059.1 - 2.2e-06 27.0 0.1 0.047 12.8 0.0 2.6 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_4 PF08386.5 EXF77059.1 - 2.8e-06 27.1 0.0 4.7e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 TAP-like protein Peptidase_S15 PF02129.13 EXF77059.1 - 0.00041 19.8 0.0 0.00068 19.1 0.0 1.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 EXF77059.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 0 Putative esterase Ndr PF03096.9 EXF77059.1 - 0.022 13.2 0.0 0.73 8.2 0.0 2.7 3 0 0 3 3 3 0 Ndr family Abhydrolase_2 PF02230.11 EXF77059.1 - 0.034 13.5 0.0 7.3 5.9 0.0 2.5 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase FSH1 PF03959.8 EXF77059.1 - 0.057 12.8 0.0 0.085 12.2 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Hydrolase_4 PF12146.3 EXF77059.1 - 0.074 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase Peptidase_S8 PF00082.17 EXF77061.1 - 8.8e-37 126.7 5.9 1.3e-36 126.2 4.1 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EXF77061.1 - 5.8e-09 36.4 0.0 1e-08 35.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 ADH_N PF08240.7 EXF77062.1 - 3.4e-28 97.5 1.0 5.2e-28 96.9 0.2 1.6 2 0 0 2 2 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF77062.1 - 1.4e-10 40.8 0.2 3.6e-10 39.5 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EXF77062.1 - 5.6e-06 25.8 0.1 1.3e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated HI0933_like PF03486.9 EXF77062.1 - 0.0013 17.2 0.1 0.0039 15.6 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.16 EXF77062.1 - 0.01 15.4 0.2 0.021 14.4 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 EXF77062.1 - 0.019 15.3 0.3 0.23 11.8 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF77062.1 - 0.035 13.0 0.1 0.052 12.4 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF77062.1 - 0.04 12.7 0.3 0.061 12.1 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain Shikimate_DH PF01488.15 EXF77062.1 - 0.05 13.7 0.1 0.1 12.6 0.0 1.5 2 0 0 2 2 1 0 Shikimate / quinate 5-dehydrogenase Methyltransf_31 PF13847.1 EXF77062.1 - 0.055 13.0 0.0 0.098 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EXF77062.1 - 0.061 13.8 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.13 EXF77062.1 - 0.07 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain FAD_binding_3 PF01494.14 EXF77062.1 - 0.087 11.8 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EXF77062.1 - 0.09 12.8 0.1 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EXF77062.1 - 0.15 11.7 0.1 0.21 11.2 0.1 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Iso_dh PF00180.15 EXF77065.1 - 4.8e-83 278.9 0.0 5.7e-83 278.7 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ldh_1_N PF00056.18 EXF77066.1 - 9.2e-44 148.6 0.3 1.3e-43 148.1 0.2 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EXF77066.1 - 4.4e-39 133.9 0.0 5.9e-39 133.5 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EXF77066.1 - 1e-05 24.3 0.0 1.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EXF77066.1 - 0.04 13.9 0.3 0.079 12.9 0.2 1.5 1 0 0 1 1 1 0 NADH(P)-binding Semialdhyde_dh PF01118.19 EXF77066.1 - 0.069 13.4 0.1 0.35 11.1 0.0 2.1 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Fungal_trans PF04082.13 EXF77067.1 - 9.1e-16 57.5 1.1 5.1e-15 55.0 0.8 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Ebola_NP PF05505.7 EXF77068.1 - 0.094 10.7 5.1 0.11 10.5 3.5 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein 2-Hacid_dh_C PF02826.14 EXF77069.1 - 6.2e-56 188.3 0.0 1.2e-55 187.3 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EXF77069.1 - 1.7e-20 72.8 0.0 1.9e-20 72.6 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EXF77069.1 - 0.00072 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_hydro_7 PF00840.15 EXF77070.1 - 1.2e-190 633.5 22.0 1.4e-190 633.3 15.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Zn_clus PF00172.13 EXF77071.1 - 1.9e-09 37.2 9.2 3e-09 36.6 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF77071.1 - 1.3e-05 24.2 0.3 3e-05 23.0 0.2 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Neur_chan_memb PF02932.11 EXF77071.1 - 3.6 7.3 5.8 8.2 6.2 4.0 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tim54 PF11711.3 EXF77071.1 - 5.1 5.5 8.8 9.2 4.7 6.1 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 AIF_C PF14721.1 EXF77071.1 - 7.8 6.7 8.6 21 5.3 5.9 1.7 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term HrpE PF06188.7 EXF77072.1 - 0.04 13.6 1.1 0.077 12.7 0.8 1.5 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E DivIVA PF05103.8 EXF77072.1 - 0.64 10.0 7.6 0.13 12.3 1.2 2.4 3 0 0 3 3 3 0 DivIVA protein Pyr_redox_3 PF13738.1 EXF77073.1 - 8.6e-27 94.5 0.0 1.5e-26 93.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EXF77073.1 - 9.9e-16 57.0 0.0 2.9e-14 52.1 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EXF77073.1 - 4.1e-12 45.6 0.1 1.7e-10 40.3 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EXF77073.1 - 2.5e-11 43.8 0.0 4e-10 39.9 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EXF77073.1 - 7.8e-05 22.7 0.0 0.011 15.8 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EXF77073.1 - 0.00028 21.2 0.0 1.1 9.7 0.0 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF77073.1 - 0.00052 18.9 0.0 0.005 15.7 0.0 2.2 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EXF77073.1 - 0.00075 18.4 0.0 0.036 12.9 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain 2-Hacid_dh_C PF02826.14 EXF77073.1 - 0.0014 17.8 0.0 0.017 14.2 0.0 2.1 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_9 PF13454.1 EXF77073.1 - 0.0018 18.0 0.2 2 8.2 0.0 3.2 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EXF77073.1 - 0.003 17.5 0.0 0.0084 16.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF77073.1 - 0.0038 16.1 0.3 0.38 9.6 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase ApbA PF02558.11 EXF77073.1 - 0.0065 15.9 0.1 0.17 11.3 0.0 2.6 2 1 1 3 3 3 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EXF77073.1 - 0.0086 15.7 0.0 0.3 10.7 0.0 2.2 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EXF77073.1 - 0.0097 14.9 0.0 0.028 13.4 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EXF77073.1 - 0.019 13.4 0.0 0.075 11.4 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein LigB PF02900.13 EXF77073.1 - 0.046 12.7 0.0 0.11 11.4 0.0 1.6 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase Lycopene_cycl PF05834.7 EXF77073.1 - 0.056 12.3 0.1 0.26 10.1 0.0 2.1 3 0 0 3 3 3 0 Lycopene cyclase protein IlvN PF07991.7 EXF77073.1 - 0.1 11.9 0.0 1.1 8.6 0.0 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain UDPG_MGDP_dh_N PF03721.9 EXF77073.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_N PF08240.7 EXF77074.1 - 7.4e-31 106.1 0.6 7.4e-31 106.1 0.4 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF77074.1 - 1.3e-18 66.7 0.1 2.5e-18 65.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EXF77074.1 - 0.0055 15.8 0.0 0.0097 15.0 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EXF77074.1 - 0.006 16.2 0.2 0.01 15.4 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 EXF77074.1 - 0.05 13.4 0.2 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EXF77074.1 - 0.054 12.8 0.0 0.095 12.0 0.0 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain adh_short PF00106.20 EXF77074.1 - 0.082 12.8 0.6 0.14 12.0 0.4 1.3 1 0 0 1 1 1 0 short chain dehydrogenase UDPGT PF00201.13 EXF77075.1 - 6.6e-13 48.0 0.0 9.9e-13 47.4 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 EXF77075.1 - 0.0065 16.2 0.0 0.012 15.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Ribosomal_L36e PF01158.13 EXF77075.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L36e Cut8_N PF14482.1 EXF77076.1 - 0.19 11.7 6.6 1.2 9.2 1.4 2.8 2 1 0 2 2 2 0 Cut8 proteasome-binding domain Candida_ALS PF05792.8 EXF77077.1 - 5.9e-07 29.4 74.9 9.2e-05 22.4 6.5 157.9 161 3 1 162 162 162 88 Candida agglutinin-like (ALS) DUF3703 PF12487.3 EXF77077.1 - 4 7.1 1.3 1.2e+02 2.4 0.1 4.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3703) CP_ATPgrasp_1 PF04174.8 EXF77077.1 - 5.4 5.5 0.3 2.2e+02 0.2 0.0 3.8 3 1 1 4 4 4 0 A circularly permuted ATPgrasp Elicitin PF00964.12 EXF77078.1 - 4 7.4 8.6 1.7 8.6 2.2 2.7 2 1 1 3 3 3 0 Elicitin SNO PF01174.14 EXF77079.1 - 3.7e-52 176.7 0.0 7.6e-41 139.8 0.0 2.1 1 1 1 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.9 EXF77079.1 - 7.9e-08 32.0 0.0 9.5e-07 28.5 0.0 2.1 2 0 0 2 2 2 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EXF77079.1 - 5.9e-05 22.5 0.0 0.069 12.5 0.0 2.1 2 0 0 2 2 2 2 Glutamine amidotransferase class-I DUF4066 PF13278.1 EXF77079.1 - 0.00097 18.4 0.0 0.0019 17.5 0.0 1.4 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EXF77079.1 - 0.0012 18.2 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.12 EXF77079.1 - 0.0047 16.6 0.0 0.007 16.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 SOR_SNZ PF01680.12 EXF77080.1 - 8.4e-104 345.6 7.0 1.1e-103 345.2 4.8 1.1 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.9 EXF77080.1 - 1.7e-09 37.1 4.6 6.2e-07 28.7 0.1 2.4 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG His_biosynth PF00977.16 EXF77080.1 - 0.00027 20.2 0.5 0.12 11.5 0.0 3.1 2 1 1 3 3 3 1 Histidine biosynthesis protein IGPS PF00218.16 EXF77080.1 - 0.0012 17.9 0.6 0.0048 15.9 0.0 2.2 3 0 0 3 3 3 1 Indole-3-glycerol phosphate synthase Dus PF01207.12 EXF77080.1 - 0.0027 16.6 0.5 0.56 8.9 0.0 2.5 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.9 EXF77080.1 - 0.012 14.5 0.7 0.2 10.5 0.0 2.5 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Trp_syntA PF00290.15 EXF77080.1 - 0.051 12.0 0.1 0.08 11.4 0.0 1.3 1 0 0 1 1 1 0 Tryptophan synthase alpha chain NMO PF03060.10 EXF77080.1 - 0.75 8.8 10.5 0.078 12.1 1.3 2.4 2 1 0 2 2 2 0 Nitronate monooxygenase WD40 PF00400.27 EXF77082.1 - 3.1e-17 61.7 2.7 0.00045 19.9 0.2 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 EXF77082.1 - 0.09 10.8 0.0 2.7 6.0 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 DUF3237 PF11578.3 EXF77083.1 - 6.1e-35 119.7 0.0 7e-35 119.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3237) GRAM PF02893.15 EXF77084.1 - 1e-26 92.2 0.4 9.2e-15 53.9 0.0 3.4 3 0 0 3 3 3 3 GRAM domain Glyco_transf_28 PF03033.15 EXF77084.1 - 1.7e-25 89.3 0.0 4e-25 88.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain PH PF00169.24 EXF77084.1 - 7.7e-15 54.9 0.0 4.5e-14 52.5 0.0 2.4 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EXF77084.1 - 1.8e-05 24.9 0.3 9.9e-05 22.5 0.2 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.1 EXF77084.1 - 4.6e-05 23.4 0.2 0.00017 21.6 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain UDPGT PF00201.13 EXF77084.1 - 5.7e-05 21.8 0.0 9.5e-05 21.1 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase FAM75 PF14650.1 EXF77085.1 - 0.12 11.7 4.1 0.19 11.0 2.8 1.4 1 1 0 1 1 1 0 FAM75 family NIF PF03031.13 EXF77086.1 - 8.7e-28 96.9 0.1 2.5e-27 95.4 0.0 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EXF77086.1 - 1e-08 34.9 0.2 3.2e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.21 EXF77086.1 - 2.9e-08 33.7 0.0 9.3e-08 32.1 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain GRIM-19 PF06212.7 EXF77087.1 - 1.3e-05 24.9 0.8 6.4e-05 22.6 0.6 2.0 2 1 0 2 2 2 1 GRIM-19 protein FAD_binding_3 PF01494.14 EXF77088.1 - 9.4e-21 74.2 0.1 8.8e-12 44.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EXF77088.1 - 1.1e-08 34.3 0.5 0.00019 20.4 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF77088.1 - 6.6e-08 32.4 0.3 3e-07 30.3 0.2 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EXF77088.1 - 1.5e-06 28.4 0.1 5.1e-05 23.5 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EXF77088.1 - 3.7e-05 22.5 0.4 0.00079 18.1 0.1 2.3 2 0 0 2 2 2 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EXF77088.1 - 4.2e-05 23.5 0.3 9.6e-05 22.3 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF77088.1 - 9.6e-05 21.0 0.1 0.00038 19.0 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EXF77088.1 - 0.00024 20.2 0.1 0.00041 19.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EXF77088.1 - 0.00028 19.8 1.8 0.00041 19.3 0.2 2.0 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.2 EXF77088.1 - 0.00065 18.8 0.1 0.001 18.2 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EXF77088.1 - 0.0044 16.1 0.3 2.2 7.2 0.1 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase ApbA PF02558.11 EXF77088.1 - 0.0044 16.4 0.2 0.0079 15.6 0.2 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 EXF77088.1 - 0.0078 15.1 1.0 0.022 13.6 0.7 1.7 1 1 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EXF77088.1 - 0.025 13.5 0.4 0.17 10.7 0.3 2.0 1 1 0 1 1 1 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 EXF77088.1 - 0.025 14.3 0.5 0.76 9.5 0.1 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EXF77088.1 - 0.047 13.7 0.1 0.25 11.3 0.1 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EXF77088.1 - 0.071 12.7 0.2 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EXF77088.1 - 0.082 12.9 0.3 0.14 12.1 0.2 1.3 1 0 0 1 1 1 0 NADH(P)-binding NAD_binding_7 PF13241.1 EXF77088.1 - 0.086 13.1 0.0 0.19 12.0 0.0 1.6 1 1 0 1 1 1 0 Putative NAD(P)-binding Shikimate_DH PF01488.15 EXF77088.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Bac_rhamnosid PF05592.6 EXF77089.1 - 6.8e-24 83.9 0.0 1.2e-22 79.8 0.0 2.1 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase T2SN PF01203.14 EXF77089.1 - 0.0093 15.5 0.0 0.024 14.1 0.0 1.7 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein N AsmA PF05170.9 EXF77089.1 - 0.044 12.4 0.0 0.06 11.9 0.0 1.1 1 0 0 1 1 1 0 AsmA family DUF608 PF04685.8 EXF77089.1 - 0.061 12.0 0.2 0.096 11.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF608 DUF1080 PF06439.6 EXF77089.1 - 0.069 13.0 0.0 0.36 10.6 0.0 2.1 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1080) Cnd1 PF12717.2 EXF77090.1 - 2.3e-56 190.4 4.6 4e-52 176.6 0.4 3.2 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 EXF77090.1 - 3e-56 189.7 1.2 1.8e-55 187.2 0.0 2.7 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 EXF77090.1 - 1.5e-10 41.2 2.4 0.00012 22.2 0.1 4.9 3 2 1 4 4 4 2 HEAT repeats HEAT PF02985.17 EXF77090.1 - 2.4e-06 27.1 11.3 0.014 15.4 0.0 6.4 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.1 EXF77090.1 - 6.1e-05 23.3 6.9 0.029 14.8 0.2 5.0 4 0 0 4 4 4 2 HEAT-like repeat Cnd3 PF12719.2 EXF77090.1 - 0.0052 15.8 1.9 0.04 12.9 1.3 2.6 1 1 0 1 1 1 1 Nuclear condensing complex subunits, C-term domain DUF2435 PF10363.4 EXF77090.1 - 0.0094 15.8 0.0 1.8 8.5 0.0 3.7 2 1 1 3 3 3 1 Protein of unknown function (DUF2435) Pkinase PF00069.20 EXF77091.1 - 1.6e-42 145.4 0.0 1.7e-38 132.2 0.0 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EXF77091.1 - 4.9e-15 55.3 0.0 9.1e-09 34.7 0.0 3.6 4 0 0 4 4 4 2 Protein tyrosine kinase APH PF01636.18 EXF77091.1 - 7e-06 25.9 0.1 0.11 12.1 0.0 2.6 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EXF77091.1 - 0.0042 16.0 0.0 0.18 10.7 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EXF77091.1 - 0.031 13.3 0.0 1.4 7.9 0.0 2.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family PTRF_SDPR PF15237.1 EXF77091.1 - 0.085 12.2 1.3 0.14 11.5 0.9 1.2 1 0 0 1 1 1 0 PTRF/SDPR family Ribosomal_L18e PF00828.14 EXF77092.1 - 2.8e-34 118.2 0.1 3.8e-34 117.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Helicase_C_2 PF13307.1 EXF77093.1 - 6.9e-59 198.5 0.0 2.4e-58 196.7 0.0 2.0 2 0 0 2 2 2 1 Helicase C-terminal domain DEAD_2 PF06733.10 EXF77093.1 - 2e-45 154.3 0.0 3.5e-45 153.5 0.0 1.4 1 0 0 1 1 1 1 DEAD_2 ResIII PF04851.10 EXF77093.1 - 0.13 12.0 0.1 23 4.7 0.0 2.7 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit TPR_12 PF13424.1 EXF77094.1 - 1.4e-12 47.4 2.2 4.8e-07 29.6 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EXF77094.1 - 5.7e-11 41.8 5.7 1.2e-07 31.3 0.2 3.7 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 EXF77094.1 - 7.3e-11 41.1 8.2 0.01 15.4 0.0 4.4 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EXF77094.1 - 1e-08 34.3 4.3 0.58 10.0 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EXF77094.1 - 1.4e-08 33.9 2.9 0.0041 16.7 0.0 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EXF77094.1 - 5.3e-07 29.0 7.9 0.049 13.5 0.0 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EXF77094.1 - 1.8e-06 28.1 1.2 0.24 11.7 0.0 3.9 2 1 1 3 3 3 3 Tetratricopeptide repeat NACHT PF05729.7 EXF77094.1 - 5.5e-05 22.8 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EXF77094.1 - 0.00011 22.1 0.0 0.00047 20.1 0.0 2.1 1 0 0 1 1 1 1 AAA ATPase domain TPR_16 PF13432.1 EXF77094.1 - 0.00037 21.0 0.2 0.27 11.9 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EXF77094.1 - 0.0014 18.7 0.6 0.026 14.6 0.3 2.9 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EXF77094.1 - 0.0014 18.9 1.0 15 6.2 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2075 PF09848.4 EXF77094.1 - 0.0089 15.0 0.0 0.019 13.9 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) TPR_14 PF13428.1 EXF77094.1 - 0.012 16.1 7.3 9 7.2 0.0 5.6 4 2 1 5 5 5 0 Tetratricopeptide repeat AAA_22 PF13401.1 EXF77094.1 - 0.015 15.3 0.0 0.084 13.0 0.0 2.3 1 1 0 1 1 1 0 AAA domain DUF3783 PF12646.2 EXF77094.1 - 0.041 13.6 0.0 16 5.3 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3783) TPR_17 PF13431.1 EXF77094.1 - 0.075 13.2 4.8 0.53 10.6 0.1 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat RNA_helicase PF00910.17 EXF77094.1 - 0.1 12.7 0.1 0.56 10.4 0.0 2.3 2 0 0 2 2 2 0 RNA helicase TPR_10 PF13374.1 EXF77094.1 - 0.17 11.8 2.4 12 5.9 0.0 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat FlgN PF05130.7 EXF77094.1 - 0.19 11.9 4.7 0.31 11.2 0.2 3.4 3 0 0 3 3 2 0 FlgN protein DUF3275 PF11679.3 EXF77095.1 - 0.34 10.5 4.8 0.49 9.9 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) SnoaL_2 PF12680.2 EXF77096.1 - 7.2e-07 29.5 0.0 8.8e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EXF77096.1 - 0.019 14.5 0.0 0.13 11.8 0.0 1.9 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase Glyco_hydro_43 PF04616.9 EXF77097.1 - 2.7e-60 203.8 12.1 9.2e-54 182.4 2.3 2.4 2 0 0 2 2 2 2 Glycosyl hydrolases family 43 Laminin_G_3 PF13385.1 EXF77097.1 - 6.5e-21 75.2 2.9 6.5e-21 75.2 2.0 3.0 2 1 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Glyco_hydro_32N PF00251.15 EXF77097.1 - 4.3e-08 32.8 8.4 0.0013 18.1 0.6 3.2 3 0 0 3 3 3 2 Glycosyl hydrolases family 32 N-terminal domain Xylanase PF13201.1 EXF77097.1 - 1.6e-06 27.2 0.0 3.6e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Putative glycoside hydrolase xylanase Sialidase PF02973.11 EXF77097.1 - 0.0029 16.6 0.1 0.0053 15.7 0.1 1.4 1 0 0 1 1 1 1 Sialidase, N-terminal domain Pectate_lyase PF03211.8 EXF77098.1 - 1.9e-77 259.5 6.8 2.2e-77 259.2 4.7 1.0 1 0 0 1 1 1 1 Pectate lyase HAD_2 PF13419.1 EXF77099.1 - 5.3e-25 88.6 0.0 6.5e-25 88.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EXF77099.1 - 6e-06 25.8 0.0 1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EXF77099.1 - 0.00019 21.9 0.0 0.0029 18.0 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3226 PF11536.3 EXF77099.1 - 0.018 14.5 0.0 0.038 13.4 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3226) NmrA PF05368.8 EXF77100.1 - 1.6e-18 66.8 0.1 1.9e-18 66.5 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF77100.1 - 1.4e-11 44.7 0.4 3.8e-11 43.3 0.0 1.8 1 1 1 2 2 2 1 NADH(P)-binding DapB_N PF01113.15 EXF77100.1 - 0.02 14.7 0.1 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 EXF77100.1 - 0.42 10.5 2.9 1.4 8.8 0.2 2.9 3 1 0 3 3 3 0 short chain dehydrogenase adh_short PF00106.20 EXF77101.1 - 5.2e-19 68.7 0.0 4.5e-18 65.7 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EXF77101.1 - 2.5e-09 37.0 0.0 3.7e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF77101.1 - 8.5e-09 35.5 0.0 1.2e-07 31.7 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Saccharop_dh PF03435.13 EXF77101.1 - 0.00024 20.1 0.1 0.00036 19.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EXF77101.1 - 0.00026 20.5 0.0 0.00052 19.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF77101.1 - 0.0045 17.0 0.0 0.018 15.0 0.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EXF77101.1 - 0.015 14.2 0.0 0.019 13.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EXF77101.1 - 0.017 13.8 0.0 0.027 13.1 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Abhydrolase_2 PF02230.11 EXF77103.1 - 1.4e-25 90.0 0.4 1.9e-11 43.8 0.0 3.0 2 1 1 3 3 3 3 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EXF77103.1 - 2.1e-07 31.0 0.3 0.00017 21.5 0.2 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF77103.1 - 7e-07 29.1 0.0 2.3e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF77103.1 - 8.5e-06 25.1 0.2 0.00028 20.1 0.0 3.0 3 1 1 4 4 4 1 Prolyl oligopeptidase family LIP PF03583.9 EXF77103.1 - 0.00037 19.7 0.2 0.00069 18.8 0.0 1.4 2 0 0 2 2 2 1 Secretory lipase BAAT_C PF08840.6 EXF77103.1 - 0.0068 16.1 0.2 0.019 14.7 0.0 1.7 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal NAD_binding_10 PF13460.1 EXF77104.1 - 2.4e-16 60.2 0.0 4.8e-16 59.2 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EXF77104.1 - 0.0073 15.5 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Abhydrolase_6 PF12697.2 EXF77105.1 - 8.1e-09 35.6 0.5 1.4e-08 34.9 0.1 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF77105.1 - 6.6e-05 22.7 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF77105.1 - 0.0004 20.0 0.0 0.0025 17.4 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold HET PF06985.6 EXF77106.1 - 2.1e-21 76.5 7.2 4.1e-19 69.1 0.7 2.5 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) PCMT PF01135.14 EXF77107.1 - 1e-56 191.8 0.0 1.5e-56 191.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EXF77107.1 - 1.7e-05 24.4 0.0 2.5e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF77107.1 - 0.00015 22.3 0.0 0.00024 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EXF77107.1 - 0.0013 18.4 0.0 0.0021 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF77107.1 - 0.0016 18.4 0.0 0.0025 17.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF77107.1 - 0.0022 17.4 0.0 0.0043 16.4 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EXF77107.1 - 0.038 13.1 0.0 0.072 12.1 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EXF77107.1 - 0.038 13.6 0.0 0.056 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.12 EXF77107.1 - 0.064 12.3 0.0 0.097 11.7 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase MetW PF07021.7 EXF77107.1 - 0.077 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_11 PF08241.7 EXF77107.1 - 0.1 13.0 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain DUF2370 PF10176.4 EXF77108.1 - 7.8e-83 277.3 0.1 7.8e-83 277.3 0.1 2.2 1 1 1 3 3 3 1 Protein of unknown function (DUF2370) Mito_carr PF00153.22 EXF77109.1 - 1.4e-56 188.1 6.1 4.7e-23 80.7 0.2 4.0 4 0 0 4 4 4 4 Mitochondrial carrier protein Se-cys_synth_N PF12390.3 EXF77111.1 - 0.078 13.0 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Selenocysteine synthase N terminal Fer4 PF00037.22 EXF77113.1 - 1.5e-13 49.7 16.5 5.4e-08 32.1 2.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EXF77113.1 - 5.8e-12 45.8 10.7 9.7e-12 45.0 7.4 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EXF77113.1 - 4.3e-10 39.7 8.3 9e-10 38.6 5.7 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EXF77113.1 - 5.6e-10 39.8 18.4 4.5e-07 30.5 7.3 2.6 2 1 1 3 3 3 2 4Fe-4S double cluster binding domain Fer4_10 PF13237.1 EXF77113.1 - 1.3e-09 37.6 22.0 4.3e-08 32.8 8.3 1.7 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_21 PF14697.1 EXF77113.1 - 5.5e-09 35.7 31.9 6.9e-06 25.8 8.5 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.2 EXF77113.1 - 9.9e-08 31.4 14.8 0.00033 20.4 1.7 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 EXF77113.1 - 1.2e-07 31.6 20.5 2.3e-05 24.3 8.1 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.2 EXF77113.1 - 2.3e-07 30.3 17.1 0.0012 18.5 3.6 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.2 EXF77113.1 - 5.5e-06 26.2 12.7 0.00059 19.9 2.1 2.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EXF77113.1 - 1.2e-05 25.5 10.3 0.00062 20.0 7.7 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 EXF77113.1 - 2.9e-05 24.4 9.8 0.011 16.1 0.7 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EXF77113.1 - 0.01 16.1 15.4 0.3 11.4 3.2 2.7 2 1 1 3 3 3 0 4Fe-4S single cluster domain Fer4_15 PF13459.1 EXF77113.1 - 0.014 15.9 13.0 0.22 12.1 1.1 2.8 2 1 0 2 2 2 0 4Fe-4S single cluster domain Fer4_3 PF12798.2 EXF77113.1 - 0.074 13.6 16.9 0.16 12.5 2.4 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EXF77113.1 - 0.13 12.4 4.9 0.14 12.3 0.1 2.4 1 1 1 2 2 2 0 c-SKI Smad4 binding domain PP-binding PF00550.20 EXF77114.1 - 1.5e-10 41.1 0.2 2.2e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EXF77114.1 - 6.3e-06 26.1 0.2 8e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 Acyl-carrier zf-CCCH PF00642.19 EXF77115.1 - 1.9e-10 40.1 8.3 3.4e-05 23.4 1.5 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EXF77115.1 - 0.013 15.4 16.4 0.03 14.3 2.7 2.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Transp_cyt_pur PF02133.10 EXF77116.1 - 1.6e-24 86.2 26.5 1.3e-23 83.3 18.1 2.0 1 1 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Glyco_hydro_47 PF01532.15 EXF77117.1 - 2.6e-166 553.7 0.0 3e-166 553.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Alpha-L-AF_C PF06964.7 EXF77118.1 - 2e-40 138.4 0.2 4.3e-40 137.3 0.1 1.6 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus FlgD_ig PF13860.1 EXF77118.1 - 0.005 16.5 0.5 0.01 15.5 0.4 1.4 1 0 0 1 1 1 1 FlgD Ig-like domain Sugar_tr PF00083.19 EXF77119.1 - 1.2e-97 327.3 15.5 1.4e-97 327.1 10.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF77119.1 - 2.6e-34 118.5 28.8 2.7e-25 88.8 7.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EXF77119.1 - 0.0083 15.8 0.0 0.79 9.5 0.0 2.7 2 0 0 2 2 2 1 MFS_1 like family Shisa PF13908.1 EXF77120.1 - 0.0038 17.4 0.0 0.004 17.3 0.0 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator RCR PF12273.3 EXF77120.1 - 0.0093 16.5 0.2 0.0093 16.5 0.2 1.7 2 0 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red DUF1183 PF06682.7 EXF77120.1 - 0.047 13.2 2.0 0.1 12.1 1.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) CD34_antigen PF06365.7 EXF77120.1 - 0.082 12.5 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family EphA2_TM PF14575.1 EXF77120.1 - 0.11 12.8 0.0 0.15 12.4 0.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Adeno_E3_CR2 PF02439.10 EXF77120.1 - 0.11 12.0 5.9 0.17 11.4 4.1 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Mid2 PF04478.7 EXF77121.1 - 0.0055 16.1 0.8 0.016 14.6 0.1 1.9 1 1 1 2 2 2 1 Mid2 like cell wall stress sensor CD99L2 PF12301.3 EXF77121.1 - 0.0069 16.0 0.1 0.014 15.0 0.1 1.5 1 0 0 1 1 1 1 CD99 antigen like protein 2 Oxidored_q1_C PF01010.14 EXF77121.1 - 0.052 13.0 0.1 0.082 12.4 0.0 1.3 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I) subunit C-terminus DUF1191 PF06697.7 EXF77121.1 - 0.083 11.6 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) adh_short PF00106.20 EXF77122.1 - 4.4e-18 65.7 0.0 8.5e-18 64.8 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF77122.1 - 1.3e-08 34.7 0.0 1.9e-06 27.6 0.0 2.2 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EXF77122.1 - 0.008 15.9 0.1 0.079 12.7 0.0 2.3 2 1 1 3 3 3 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EXF77122.1 - 0.012 15.0 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.1 EXF77123.1 - 7.6e-23 81.6 0.0 2.7e-21 76.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EXF77123.1 - 5.5e-16 57.8 0.0 1.8e-15 56.1 0.0 1.8 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EXF77123.1 - 1.2e-10 41.2 0.0 6.3e-10 38.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EXF77123.1 - 6.3e-06 25.3 0.0 0.00011 21.2 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EXF77123.1 - 0.00044 20.0 0.4 0.041 13.6 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Amino_oxidase PF01593.19 EXF77123.1 - 0.0013 17.8 0.0 0.075 12.0 0.0 2.3 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 EXF77123.1 - 0.03 13.2 0.0 0.81 8.5 0.0 2.7 3 0 0 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.12 EXF77123.1 - 0.16 10.9 0.0 26 3.7 0.0 3.0 3 0 0 3 3 3 0 Thi4 family Fungal_trans PF04082.13 EXF77124.1 - 1.5e-08 33.8 0.3 3e-08 32.8 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF77124.1 - 1e-05 25.3 8.0 1.7e-05 24.6 5.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EXF77125.1 - 2.4e-32 112.0 31.9 2.4e-32 112.0 22.1 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Tox-GHH PF15636.1 EXF77125.1 - 0.061 12.9 0.2 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin ESSS PF10183.4 EXF77125.1 - 0.41 11.0 2.2 0.61 10.5 0.1 2.4 3 0 0 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Lactamase_B PF00753.22 EXF77126.1 - 9.3e-09 35.2 0.2 1.3e-08 34.7 0.1 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EXF77126.1 - 0.00023 20.7 0.0 0.00036 20.1 0.0 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Pyr_redox_3 PF13738.1 EXF77127.1 - 2.2e-28 99.7 0.0 3.3e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EXF77127.1 - 1.4e-13 49.9 0.0 2.7e-13 48.9 0.0 1.4 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EXF77127.1 - 5.8e-10 38.6 0.0 1.7e-07 30.4 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EXF77127.1 - 7.4e-10 39.0 0.0 1.2e-05 25.2 0.0 3.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF77127.1 - 1.4e-08 34.6 0.1 1.1e-07 31.7 0.0 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF77127.1 - 3.2e-05 23.0 0.0 0.00018 20.5 0.0 2.2 2 1 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EXF77127.1 - 0.00022 20.4 0.0 0.00069 18.7 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EXF77127.1 - 0.00032 19.6 0.0 0.00074 18.4 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EXF77127.1 - 0.0006 19.6 0.1 0.69 9.6 0.2 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EXF77127.1 - 0.0024 16.3 0.0 0.086 11.2 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.22 EXF77127.1 - 0.017 15.5 0.4 3.3 8.1 0.3 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EXF77127.1 - 0.021 15.0 0.0 0.51 10.6 0.0 2.4 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.14 EXF77127.1 - 0.026 13.5 0.0 1.1 8.2 0.0 2.2 2 0 0 2 2 2 0 FAD binding domain Lycopene_cycl PF05834.7 EXF77127.1 - 0.055 12.3 0.0 0.13 11.1 0.0 1.8 1 1 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.2 EXF77127.1 - 0.074 12.1 0.1 0.14 11.1 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Abhydrolase_3 PF07859.8 EXF77128.1 - 4.2e-54 183.3 0.0 5.5e-54 182.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EXF77128.1 - 2e-15 56.5 0.3 5.7e-15 55.0 0.2 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.16 EXF77128.1 - 4.4e-05 22.7 0.1 0.041 13.0 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EXF77128.1 - 0.0012 18.6 0.0 0.002 17.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EXF77128.1 - 0.03 13.5 0.0 0.14 11.4 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family Lipoprotein_21 PF14041.1 EXF77128.1 - 0.035 14.0 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 LppP/LprE lipoprotein Chlorophyllase2 PF12740.2 EXF77128.1 - 0.043 12.7 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme adh_short_C2 PF13561.1 EXF77129.1 - 4.2e-25 88.9 0.1 5.3e-25 88.5 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EXF77129.1 - 3.3e-20 72.6 2.8 4.6e-20 72.2 1.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Ecm33 PF12454.3 EXF77129.1 - 0.018 14.8 0.5 5.8 6.8 0.1 2.7 2 0 0 2 2 2 0 GPI-anchored cell wall organization protein E1-N PF14463.1 EXF77129.1 - 0.98 9.0 4.7 6.9 6.2 0.0 3.0 2 1 0 3 3 3 0 E1 N-terminal domain ADH_N PF08240.7 EXF77130.1 - 1.2e-19 70.1 1.6 2e-19 69.3 1.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF77130.1 - 2e-13 50.0 0.0 3.6e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF77130.1 - 5.9e-11 43.3 0.0 1.2e-10 42.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EXF77130.1 - 0.067 12.7 0.1 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AMP-binding PF00501.23 EXF77131.1 - 1.7e-68 230.9 0.0 1.2e-50 172.1 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.1 EXF77131.1 - 1.4e-15 57.9 0.0 3.6e-15 56.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Vhr1 PF04001.8 EXF77131.1 - 0.14 12.0 0.0 0.31 10.9 0.0 1.5 1 0 0 1 1 1 0 Transcription factor Vhr1 AA_permease_2 PF13520.1 EXF77132.1 - 6.7e-52 176.4 47.2 8.6e-52 176.0 32.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF77132.1 - 3.1e-22 78.5 39.0 3.8e-22 78.2 27.0 1.0 1 0 0 1 1 1 1 Amino acid permease DUF3493 PF11998.3 EXF77132.1 - 0.048 13.5 0.0 0.048 13.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3493) DUF1182 PF06681.8 EXF77132.1 - 3.1 6.9 10.2 0.054 12.7 1.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1182) Cu_amine_oxid PF01179.15 EXF77133.1 - 2.8e-170 566.5 0.0 3.4e-170 566.2 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EXF77133.1 - 1.6e-18 66.6 0.0 4.7e-18 65.1 0.0 1.8 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EXF77133.1 - 1.8e-12 47.1 0.0 3.8e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Myosin_tail_1 PF01576.14 EXF77134.1 - 0.00026 18.9 71.7 0.00026 18.9 49.7 3.3 1 1 2 3 3 3 1 Myosin tail IncA PF04156.9 EXF77134.1 - 0.0066 16.0 176.0 0.0076 15.8 14.4 9.0 1 1 8 9 9 9 5 IncA protein CENP-Q PF13094.1 EXF77134.1 - 0.0079 16.2 31.4 0.0079 16.2 21.7 8.3 1 1 6 7 7 7 1 CENP-Q, a CENPA-CAD centromere complex subunit Spc7 PF08317.6 EXF77134.1 - 0.013 14.1 159.5 0.07 11.7 9.8 7.5 1 1 5 7 7 7 0 Spc7 kinetochore protein DUF3584 PF12128.3 EXF77134.1 - 0.028 11.7 179.9 0.14 9.4 42.0 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF3584) rve_3 PF13683.1 EXF77134.1 - 0.93 9.0 15.5 6.9 6.2 0.0 7.3 4 1 3 7 7 7 0 Integrase core domain Filament PF00038.16 EXF77134.1 - 1.7 8.0 158.1 0.62 9.4 25.6 7.8 1 1 7 8 8 8 0 Intermediate filament protein Tup_N PF08581.5 EXF77134.1 - 1.9 8.7 96.0 0.026 14.7 1.9 13.4 3 2 9 14 14 14 0 Tup N-terminal YceG PF02618.11 EXF77138.1 - 0.029 13.3 0.0 0.029 13.3 0.0 1.6 2 0 0 2 2 2 0 YceG-like family DUF4604 PF15377.1 EXF77138.1 - 7.8 6.6 28.1 12 6.0 19.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) Fungal_trans_2 PF11951.3 EXF77139.1 - 9.1e-09 34.3 0.0 3.4e-06 25.9 0.0 2.4 2 1 1 3 3 3 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF77139.1 - 2.2e-07 30.6 15.5 4e-07 29.8 10.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 EXF77140.1 - 1.5e-08 34.4 7.0 2.4e-08 33.7 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF77140.1 - 0.046 12.5 2.7 0.066 12.0 1.7 1.4 1 1 0 1 1 1 0 Fungal specific transcription factor domain Synaptobrevin PF00957.16 EXF77140.1 - 0.05 13.2 0.1 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 Synaptobrevin ADH_N PF08240.7 EXF77141.1 - 1.3e-06 28.0 0.1 1.2e-05 25.0 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Carb_anhydrase PF00194.16 EXF77143.1 - 1.4e-16 60.2 0.0 9.9e-10 37.8 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase adh_short PF00106.20 EXF77146.1 - 0.0049 16.8 0.0 0.0087 15.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF77146.1 - 0.02 14.5 0.0 0.075 12.6 0.0 1.8 2 0 0 2 2 2 0 KR domain DUF258 PF03193.11 EXF77146.1 - 0.09 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Pkinase PF00069.20 EXF77147.1 - 1.2e-67 227.8 0.0 2.3e-67 226.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF77147.1 - 3.5e-37 127.8 0.0 6.5e-37 127.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF77147.1 - 5.9e-08 32.0 0.0 1.1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EXF77147.1 - 0.034 13.8 0.0 0.093 12.4 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EXF77147.1 - 0.057 12.2 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Peptidase_S66 PF02016.10 EXF77148.1 - 1.4e-53 181.6 0.0 2.4e-53 180.9 0.0 1.3 1 0 0 1 1 1 1 LD-carboxypeptidase Glyco_tranf_2_3 PF13641.1 EXF77150.1 - 5.7e-27 94.9 0.0 8.7e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EXF77150.1 - 4.1e-26 91.6 0.0 8.1e-26 90.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 EXF77150.1 - 1.6e-11 44.2 2.7 3.2e-11 43.2 1.9 1.5 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EXF77150.1 - 1.8e-09 37.1 0.0 3.7e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.10 EXF77150.1 - 2.7e-08 32.6 0.0 0.00069 18.1 0.0 3.1 2 1 0 2 2 2 2 Chitin synthase Polysacc_deac_1 PF01522.16 EXF77150.1 - 8.2e-06 25.4 0.0 3.3e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_tranf_2_4 PF13704.1 EXF77150.1 - 0.0057 16.9 0.0 0.013 15.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 EXF77150.1 - 0.0071 15.4 0.1 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF4596 PF15363.1 EXF77151.1 - 0.13 12.2 1.5 0.33 10.8 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4596) MiAMP1 PF09117.5 EXF77151.1 - 1.3 9.4 6.2 17 5.8 4.3 2.3 1 1 0 1 1 1 0 MiAMP1 COesterase PF00135.23 EXF77152.1 - 7.5e-84 282.3 0.0 1.5e-83 281.3 0.0 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF77152.1 - 6.2e-05 22.6 0.7 0.00051 19.6 0.5 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Homeobox PF00046.24 EXF77153.1 - 7.7e-13 47.8 3.3 1.6e-12 46.8 2.3 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EXF77153.1 - 0.014 15.0 0.6 0.035 13.7 0.4 1.7 1 0 0 1 1 1 0 Homeobox KN domain NARP1 PF12569.3 EXF77153.1 - 0.37 9.4 9.3 0.54 8.9 6.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 HAD_2 PF13419.1 EXF77154.1 - 2.9e-16 60.1 0.0 3.7e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EXF77154.1 - 3.2e-09 37.5 0.0 9.4e-07 29.4 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EXF77154.1 - 7.3e-09 35.2 0.0 1.4e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.2 EXF77154.1 - 2.2e-05 24.7 0.0 3.7e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase GHL6 PF14871.1 EXF77154.1 - 0.0064 16.5 0.1 0.018 15.0 0.0 1.7 2 0 0 2 2 2 1 Hypothetical glycosyl hydrolase 6 Hydrolase_6 PF13344.1 EXF77154.1 - 0.039 13.8 0.0 10 6.0 0.0 2.6 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase GN3L_Grn1 PF08701.6 EXF77155.1 - 2.4e-25 88.2 18.5 4.8e-25 87.2 12.8 1.4 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EXF77155.1 - 2e-21 76.1 0.1 2.3e-15 56.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EXF77155.1 - 2.5e-07 30.3 0.0 0.01 15.2 0.0 2.4 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EXF77155.1 - 1e-06 28.6 7.4 0.038 13.8 0.3 3.9 4 0 0 4 4 4 2 Dynamin family DUF258 PF03193.11 EXF77155.1 - 0.00042 19.5 0.1 0.00075 18.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EXF77155.1 - 0.00047 20.6 0.6 1.5 9.3 0.1 2.6 2 0 0 2 2 2 2 Miro-like protein FeoB_N PF02421.13 EXF77155.1 - 0.00084 18.6 0.3 0.017 14.3 0.0 2.5 2 1 0 2 2 2 1 Ferrous iron transport protein B TFIIA PF03153.8 EXF77155.1 - 0.026 14.4 15.4 0.042 13.7 10.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AIG1 PF04548.11 EXF77155.1 - 0.029 13.4 0.1 0.088 11.8 0.0 1.8 2 0 0 2 2 2 0 AIG1 family ArgK PF03308.11 EXF77155.1 - 0.075 11.7 5.4 0.11 11.2 0.0 2.3 2 0 0 2 2 2 0 ArgK protein AAA_16 PF13191.1 EXF77155.1 - 0.29 11.0 4.0 0.67 9.9 0.1 3.0 2 1 0 2 2 2 0 AAA ATPase domain SGT1 PF07093.6 EXF77155.1 - 2.8 6.2 14.0 4.1 5.6 9.7 1.2 1 0 0 1 1 1 0 SGT1 protein Pex14_N PF04695.8 EXF77156.1 - 0.51 10.3 4.6 0.92 9.5 3.2 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SinI PF08671.5 EXF77157.1 - 0.0028 17.0 0.2 0.0064 15.8 0.1 1.6 1 0 0 1 1 1 1 Anti-repressor SinI RNB PF00773.14 EXF77158.1 - 6.4e-94 314.8 0.0 9.4e-94 314.3 0.0 1.3 1 0 0 1 1 1 1 RNB domain PIN_4 PF13638.1 EXF77158.1 - 7.6e-11 42.2 0.4 2.4e-10 40.6 0.3 1.9 1 1 0 1 1 1 1 PIN domain CRC_subunit PF08624.5 EXF77159.1 - 8.4e-54 181.2 0.0 1.2e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Peptidase_M41 PF01434.13 EXF77160.1 - 1.4e-76 256.7 0.0 2.2e-76 256.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EXF77160.1 - 5.3e-43 146.3 0.1 2.6e-42 144.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsH_ext PF06480.10 EXF77160.1 - 5.6e-11 42.5 0.0 1.4e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.9 EXF77160.1 - 0.00046 19.9 0.0 0.0017 18.0 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EXF77160.1 - 0.0019 18.3 0.2 0.7 10.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.8 EXF77160.1 - 0.003 16.3 0.0 0.0055 15.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_17 PF13207.1 EXF77160.1 - 0.005 17.6 0.1 0.037 14.8 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EXF77160.1 - 0.0056 16.4 1.0 0.034 13.8 0.4 2.3 2 0 0 2 2 2 1 Part of AAA domain RuvB_N PF05496.7 EXF77160.1 - 0.0063 15.5 0.0 0.023 13.7 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EXF77160.1 - 0.0091 15.4 1.9 0.025 13.9 0.5 2.4 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EXF77160.1 - 0.018 14.9 0.0 0.1 12.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EXF77160.1 - 0.022 14.7 0.2 0.34 10.8 0.1 2.6 1 1 1 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 EXF77160.1 - 0.025 13.6 0.0 0.058 12.4 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 EXF77160.1 - 0.03 13.7 0.0 0.074 12.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_14 PF13173.1 EXF77160.1 - 0.042 13.7 0.0 0.18 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Fungal_trans PF04082.13 EXF77161.1 - 1.1e-30 106.3 0.1 4e-30 104.5 0.0 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF77161.1 - 9.2e-11 41.4 12.0 1.7e-10 40.6 8.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fmp27_WPPW PF10359.4 EXF77162.1 - 0.085 11.2 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Yip1 PF04893.12 EXF77163.1 - 0.029 13.8 0.5 0.057 12.9 0.3 1.6 1 0 0 1 1 1 0 Yip1 domain Syndecan PF01034.15 EXF77163.1 - 0.052 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain DUF676 PF05057.9 EXF77164.1 - 4.7e-08 32.5 0.0 8.2e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EXF77164.1 - 1.7e-07 31.0 0.2 1.7e-06 27.8 0.1 2.3 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EXF77164.1 - 3.6e-07 30.0 0.0 8.5e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF77164.1 - 3.7e-06 26.9 0.0 9.1e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family UPF0227 PF05728.7 EXF77164.1 - 0.0011 18.7 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_1 PF00561.15 EXF77164.1 - 0.0021 17.6 0.0 0.0043 16.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.3 EXF77164.1 - 0.0071 15.7 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Lipase_3 PF01764.20 EXF77164.1 - 0.01 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 EXF77164.1 - 0.013 15.1 0.0 0.031 13.8 0.0 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2305 PF10230.4 EXF77164.1 - 0.018 14.5 0.1 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Thioesterase PF00975.15 EXF77164.1 - 0.034 14.3 0.0 0.034 14.3 0.0 2.5 2 1 0 2 2 1 0 Thioesterase domain Rox3 PF08633.5 EXF77165.1 - 5.9e-42 144.1 3.3 8.8e-42 143.6 0.1 2.1 2 0 0 2 2 2 1 Rox3 mediator complex subunit PI3_PI4_kinase PF00454.22 EXF77166.1 - 4.8e-40 137.4 0.0 7e-40 136.9 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase SNF2_N PF00176.18 EXF77168.1 - 8.9e-70 234.8 0.0 1.4e-69 234.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EXF77168.1 - 3.5e-10 39.5 0.0 7.2e-10 38.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_5 PF14634.1 EXF77168.1 - 1.4e-07 31.1 2.1 2.4e-07 30.3 1.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain HIRAN PF08797.6 EXF77168.1 - 0.0067 16.3 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 HIRAN domain zf-C3HC4_3 PF13920.1 EXF77168.1 - 0.008 15.8 1.4 0.02 14.5 1.0 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EXF77168.1 - 0.016 14.8 1.5 0.054 13.1 1.1 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EXF77168.1 - 0.023 14.5 1.6 0.045 13.5 1.1 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_2 PF13923.1 EXF77168.1 - 0.035 14.1 1.6 0.084 12.9 1.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cyt-b5 PF00173.23 EXF77169.1 - 7.1e-17 60.9 0.0 3.8e-16 58.6 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_desaturase PF00487.19 EXF77169.1 - 3.9e-15 55.9 14.8 3.9e-15 55.9 10.2 2.0 1 1 1 2 2 2 1 Fatty acid desaturase MCM PF00493.18 EXF77170.1 - 6.5e-142 472.1 0.1 9.4e-142 471.6 0.1 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EXF77170.1 - 3.1e-20 72.8 1.7 4.6e-20 72.3 0.6 1.7 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EXF77170.1 - 1.5e-06 27.5 0.0 0.0002 20.5 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EXF77170.1 - 1.9e-05 24.4 0.0 4.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EXF77170.1 - 0.00064 19.3 0.0 0.0026 17.3 0.0 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 EXF77170.1 - 0.042 14.2 1.9 0.084 13.2 0.2 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EXF77170.1 - 0.044 13.2 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Vps54 PF07928.7 EXF77171.1 - 4.1e-47 159.7 0.5 3e-46 156.8 0.0 2.6 3 0 0 3 3 3 1 Vps54-like protein DUF2450 PF10475.4 EXF77171.1 - 3.4e-06 26.1 0.7 8.9e-06 24.8 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Sec8_exocyst PF04048.9 EXF77171.1 - 0.017 14.7 0.4 0.19 11.3 0.2 2.6 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain Spc7 PF08317.6 EXF77171.1 - 0.02 13.5 0.5 0.053 12.1 0.3 1.6 1 0 0 1 1 1 0 Spc7 kinetochore protein LUC7 PF03194.10 EXF77171.1 - 0.12 11.8 0.8 0.3 10.5 0.6 1.6 1 0 0 1 1 1 0 LUC7 N_terminus COG5 PF10392.4 EXF77171.1 - 0.4 10.6 5.4 13 5.7 0.9 2.9 2 0 0 2 2 2 0 Golgi transport complex subunit 5 COG2 PF06148.6 EXF77171.1 - 0.44 10.4 4.7 0.24 11.2 0.5 2.6 3 0 0 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF904 PF06005.7 EXF77171.1 - 1.7 9.0 8.7 0.15 12.3 1.0 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF904) F-box-like PF12937.2 EXF77174.1 - 8.9e-09 34.9 4.4 4.8e-08 32.5 3.0 2.3 1 1 0 1 1 1 1 F-box-like F-box PF00646.28 EXF77174.1 - 0.0042 16.7 6.4 0.005 16.4 1.6 2.7 2 1 0 2 2 2 1 F-box domain Glycogen_syn PF05693.8 EXF77175.1 - 0 1145.8 0.0 0 1145.6 0.0 1.0 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EXF77175.1 - 1.1e-05 24.9 0.0 0.016 14.6 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EXF77175.1 - 1.1e-05 25.0 0.1 2.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 EXF77175.1 - 1.5e-05 25.1 0.1 3.5e-05 24.0 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Pkinase PF00069.20 EXF77176.1 - 7.3e-67 225.2 0.0 1.2e-66 224.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF77176.1 - 4.7e-36 124.1 0.0 8.6e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF77176.1 - 5.6e-05 22.2 0.0 9.4e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF1777 PF08648.7 EXF77176.1 - 0.00042 20.0 38.8 0.00042 20.0 26.9 6.3 3 1 2 5 5 5 1 Protein of unknown function (DUF1777) Kdo PF06293.9 EXF77176.1 - 0.0029 16.7 0.1 0.0065 15.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Troponin-I_N PF11636.3 EXF77177.1 - 0.014 15.0 0.2 0.077 12.6 0.1 2.3 1 0 0 1 1 1 0 Troponin I residues 1-32 Pmp3 PF01679.12 EXF77178.1 - 1.1e-19 69.8 7.6 1.4e-19 69.5 5.3 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator CoxIIa PF08113.6 EXF77178.1 - 0.063 13.0 1.9 0.063 13.0 1.3 2.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit IIa family NapE PF06796.6 EXF77178.1 - 0.64 9.3 2.4 0.93 8.8 1.6 1.3 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE zf-RanBP PF00641.13 EXF77179.1 - 2e-18 65.1 13.3 7.1e-11 41.0 1.1 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others RRM_1 PF00076.17 EXF77179.1 - 1.7e-08 33.9 0.0 3.4e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNase_T PF00929.19 EXF77179.1 - 6.6e-07 29.7 0.0 1.1e-06 29.0 0.0 1.3 1 0 0 1 1 1 1 Exonuclease RRM_6 PF14259.1 EXF77179.1 - 1.5e-05 24.8 0.0 3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DZR PF12773.2 EXF77179.1 - 2.5 8.0 10.4 0.72 9.7 0.8 2.4 2 0 0 2 2 2 0 Double zinc ribbon WD40 PF00400.27 EXF77180.1 - 1.1e-38 129.7 0.4 9.9e-09 34.7 0.0 6.3 6 0 0 6 6 6 6 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EXF77180.1 - 6.1e-29 99.7 0.2 1.4e-28 98.5 0.2 1.7 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex Nup160 PF11715.3 EXF77180.1 - 0.097 10.7 0.3 1.4 6.9 0.0 2.5 1 1 1 2 2 2 0 Nucleoporin Nup120/160 XRN_N PF03159.13 EXF77181.1 - 4.8e-102 340.3 0.0 7.6e-102 339.7 0.0 1.3 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus SPC22 PF04573.7 EXF77182.1 - 2.2e-34 118.2 1.6 3.2e-24 85.1 0.1 2.1 2 0 0 2 2 2 2 Signal peptidase subunit Peptidase_C48 PF02902.14 EXF77183.1 - 3.7e-29 101.9 0.0 7.1e-29 100.9 0.0 1.4 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain WD40 PF00400.27 EXF77184.1 - 4e-30 102.5 3.9 1.3e-08 34.3 0.0 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EXF77184.1 - 0.019 13.1 0.0 1.4 6.9 0.1 2.6 2 1 0 2 2 2 0 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EXF77184.1 - 0.1 12.9 0.0 2.6 8.4 0.0 2.9 2 0 0 2 2 2 0 PQQ-like domain Proteasome PF00227.21 EXF77185.1 - 6.9e-34 116.7 0.0 8.5e-34 116.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DEAD PF00270.24 EXF77186.1 - 2.3e-46 157.4 0.0 3.8e-45 153.4 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF77186.1 - 2.3e-27 94.6 0.1 5.3e-27 93.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EXF77186.1 - 0.0096 15.7 0.0 0.021 14.6 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EXF77186.1 - 0.037 13.0 0.1 0.066 12.2 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF1253 PF06862.7 EXF77186.1 - 0.27 9.6 0.0 0.67 8.2 0.0 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1253) ABC_membrane PF00664.18 EXF77188.1 - 6.4e-48 163.5 35.1 3.3e-27 95.5 11.0 3.2 3 0 0 3 3 3 3 ABC transporter transmembrane region ABC_tran PF00005.22 EXF77188.1 - 1.1e-47 161.7 0.0 2.5e-27 95.8 0.0 2.8 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EXF77188.1 - 2.5e-06 27.6 0.2 1.2 9.0 0.0 4.3 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EXF77188.1 - 3.5e-06 27.1 0.3 0.12 12.3 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EXF77188.1 - 8.1e-06 25.2 0.3 0.69 9.1 0.0 3.5 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EXF77188.1 - 3.2e-05 23.1 0.8 0.016 14.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EXF77188.1 - 4.5e-05 22.8 0.6 0.12 11.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EXF77188.1 - 6.5e-05 22.8 0.3 0.19 11.6 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EXF77188.1 - 7.2e-05 21.9 0.0 0.039 13.0 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin Miro PF08477.8 EXF77188.1 - 9.1e-05 22.9 2.2 0.11 12.9 0.1 2.7 2 0 0 2 2 2 2 Miro-like protein AAA_17 PF13207.1 EXF77188.1 - 0.00016 22.4 0.5 0.3 11.9 0.2 2.9 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EXF77188.1 - 0.00058 19.5 1.5 0.49 9.9 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EXF77188.1 - 0.00097 19.2 0.2 1.5 8.9 0.0 3.2 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EXF77188.1 - 0.0011 18.4 0.4 2.4 7.5 0.0 3.2 3 0 0 3 3 3 2 AAA-like domain AAA_25 PF13481.1 EXF77188.1 - 0.0021 17.5 0.0 0.43 9.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EXF77188.1 - 0.0044 17.3 4.8 0.28 11.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.12 EXF77188.1 - 0.0044 16.8 2.3 0.1 12.3 0.3 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 TrwB_AAD_bind PF10412.4 EXF77188.1 - 0.0056 15.3 0.5 0.43 9.1 0.0 2.4 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_28 PF13521.1 EXF77188.1 - 0.011 15.6 0.4 0.054 13.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EXF77188.1 - 0.018 14.5 0.0 4.7 6.6 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family ArgK PF03308.11 EXF77188.1 - 0.02 13.6 2.0 0.44 9.2 0.2 2.3 2 0 0 2 2 2 0 ArgK protein MobB PF03205.9 EXF77188.1 - 0.023 14.4 2.2 1.5 8.4 0.2 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EXF77188.1 - 0.027 14.1 0.3 0.26 10.9 0.0 2.3 2 0 0 2 2 2 0 NACHT domain T2SE PF00437.15 EXF77188.1 - 0.031 13.1 0.1 1.1 8.1 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein Dynamin_N PF00350.18 EXF77188.1 - 0.04 13.7 2.6 0.51 10.1 0.1 2.5 2 0 0 2 2 2 0 Dynamin family AAA_18 PF13238.1 EXF77188.1 - 0.042 14.1 1.4 2.5 8.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.17 EXF77188.1 - 0.056 12.8 0.5 0.61 9.4 0.1 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ATP_bind_1 PF03029.12 EXF77188.1 - 0.24 10.8 2.3 8.2 5.8 0.2 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UPF0079 PF02367.12 EXF77188.1 - 0.28 10.8 0.9 1.3 8.6 0.0 2.4 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_15 PF13175.1 EXF77188.1 - 0.31 10.0 0.0 5.4 5.9 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 EXF77188.1 - 0.84 9.1 2.4 2.3 7.6 0.1 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EXF77188.1 - 1 8.8 3.6 1.3 8.4 0.3 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Fcf1 PF04900.7 EXF77190.1 - 7.1e-35 119.1 0.7 9.4e-35 118.7 0.0 1.5 2 0 0 2 2 2 1 Fcf1 Fungal_trans PF04082.13 EXF77191.1 - 2.7e-15 55.9 0.2 1.1e-14 53.9 0.2 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF77191.1 - 3.4e-05 23.6 10.4 5.9e-05 22.8 7.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.8 EXF77192.1 - 1.2e-74 250.5 0.0 1.6e-74 250.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF77192.1 - 0.0021 18.0 0.2 0.038 13.9 0.2 2.3 1 1 0 1 1 1 1 NADH(P)-binding DUF755 PF05501.6 EXF77192.1 - 0.25 11.4 5.7 0.43 10.6 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Xpo1 PF08389.7 EXF77193.1 - 1.7e-36 125.3 0.1 1.7e-36 125.3 0.1 3.3 3 1 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.17 EXF77193.1 - 0.00042 20.1 0.7 1.3 9.3 0.0 4.4 5 0 0 5 5 5 2 HEAT repeat Phage_C PF12025.3 EXF77193.1 - 0.0035 17.2 0.1 0.017 15.0 0.0 2.2 2 0 0 2 2 2 1 Phage protein C TipAS PF07739.8 EXF77193.1 - 0.89 9.8 3.9 19 5.6 0.0 3.4 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain DUF2347 PF09804.4 EXF77194.1 - 8.5e-110 366.4 0.0 1.1e-109 366.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2347) DUF4484 PF14831.1 EXF77194.1 - 9.8e-49 165.8 0.1 1.6e-48 165.0 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4484) SPA PF08616.5 EXF77194.1 - 5.2e-06 26.1 0.0 1.2e-05 24.9 0.0 1.5 1 1 0 1 1 1 1 Stabilization of polarity axis Acyltransferase PF01553.16 EXF77195.1 - 2.9e-33 114.1 0.0 4.5e-33 113.4 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Ribonuc_L-PSP PF01042.16 EXF77195.1 - 0.038 13.7 0.0 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 Endoribonuclease L-PSP DUF3336 PF11815.3 EXF77196.1 - 5.2e-54 181.7 4.4 8.3e-54 181.0 3.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EXF77196.1 - 1.4e-21 77.3 1.0 3.7e-21 75.9 0.0 2.2 3 0 0 3 3 3 1 Patatin-like phospholipase Arf PF00025.16 EXF77197.1 - 2.9e-66 222.0 0.0 3.2e-66 221.8 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EXF77197.1 - 1.2e-10 40.6 0.1 5.4e-07 28.6 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EXF77197.1 - 5.8e-08 32.1 0.0 7.6e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EXF77197.1 - 8e-08 32.7 0.0 1.1e-07 32.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EXF77197.1 - 8.5e-08 31.7 0.0 1.1e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.18 EXF77197.1 - 2.3e-07 30.7 0.0 3.1e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EXF77197.1 - 6.6e-06 25.4 0.0 7e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EXF77197.1 - 0.00016 21.1 0.0 0.0071 15.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EXF77197.1 - 0.11 11.9 0.0 0.24 10.8 0.0 1.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2457 PF10446.4 EXF77198.1 - 5.6e-98 328.6 18.9 5.6e-98 328.6 13.1 2.7 2 1 2 4 4 4 1 Protein of unknown function (DUF2457) F-box-like PF12937.2 EXF77200.1 - 1.1e-09 37.8 0.2 1.1e-09 37.8 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EXF77200.1 - 4.8e-08 32.4 0.6 1e-07 31.4 0.0 1.8 2 0 0 2 2 2 1 F-box domain TPR_11 PF13414.1 EXF77200.1 - 0.0012 18.4 1.4 0.049 13.2 0.0 3.1 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.23 EXF77200.1 - 0.0022 17.5 0.5 1.4 8.6 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EXF77200.1 - 0.036 14.6 0.4 0.17 12.5 0.3 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 EXF77200.1 - 0.048 13.5 6.3 2.8 8.0 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EXF77200.1 - 0.13 12.1 2.5 16 5.4 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat PRANC PF09372.5 EXF77200.1 - 0.2 11.6 0.0 0.35 10.8 0.0 1.3 1 0 0 1 1 1 0 PRANC domain TPR_16 PF13432.1 EXF77200.1 - 1.8 9.3 5.1 24 5.7 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat ADIP PF11559.3 EXF77201.1 - 1.6e-39 135.2 5.1 1.6e-39 135.2 3.5 2.2 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding DUF3384 PF11864.3 EXF77201.1 - 0.036 12.5 0.0 0.056 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3384) DUF641 PF04859.7 EXF77201.1 - 0.13 12.0 3.5 2.3 8.0 1.3 2.8 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DivIVA PF05103.8 EXF77201.1 - 1.9 8.5 7.7 3.8 7.5 3.2 2.7 2 0 0 2 2 2 0 DivIVA protein Macoilin PF09726.4 EXF77201.1 - 4.7 5.3 12.3 1.7 6.8 4.9 2.1 2 0 0 2 2 2 0 Transmembrane protein AdoMet_MTase PF07757.8 EXF77202.1 - 9.8e-39 131.9 0.0 1.5e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 EXF77202.1 - 0.0024 17.6 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EXF77202.1 - 0.088 12.4 0.1 1.4 8.6 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EXF77202.1 - 0.14 12.7 0.1 1.1 9.8 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain NMO PF03060.10 EXF77203.1 - 4.2e-41 141.1 12.7 1e-40 139.9 8.8 1.5 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EXF77203.1 - 3.7e-07 29.3 10.0 1e-06 27.9 6.9 1.6 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EXF77203.1 - 1.3e-05 24.2 10.4 1.9e-05 23.6 7.2 1.2 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EXF77203.1 - 0.0004 19.4 3.7 0.00059 18.8 2.6 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase Aldo_ket_red PF00248.16 EXF77204.1 - 5e-70 235.5 0.0 5.7e-70 235.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FliG_M PF14841.1 EXF77204.1 - 0.13 12.3 0.2 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 FliG middle domain zf-CCHC PF00098.18 EXF77205.1 - 6.5e-44 145.8 74.1 1.3e-07 31.1 2.3 9.2 9 0 0 9 9 9 9 Zinc knuckle zf-CCHC_3 PF13917.1 EXF77205.1 - 3.2e-10 39.5 51.4 0.011 15.4 0.6 8.2 2 2 6 8 8 8 7 Zinc knuckle zf-CCHC_2 PF13696.1 EXF77205.1 - 5.4e-10 38.5 50.6 0.0092 15.4 0.2 9.9 7 2 3 10 10 10 6 Zinc knuckle zf-CCHC_6 PF15288.1 EXF77205.1 - 0.013 15.2 2.6 0.013 15.2 1.8 7.9 5 1 3 8 8 8 0 Zinc knuckle zf-CCHC_4 PF14392.1 EXF77205.1 - 0.068 12.8 63.8 0.054 13.1 1.0 8.3 9 0 0 9 9 9 0 Zinc knuckle DUF1654 PF07867.6 EXF77205.1 - 0.11 11.9 0.2 0.2 11.0 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1654) HATPase_c PF02518.21 EXF77206.1 - 1.4e-29 102.0 0.3 7.5e-29 99.6 0.0 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EXF77206.1 - 3.8e-28 97.7 0.3 7.1e-28 96.8 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EXF77206.1 - 1.3e-12 47.4 0.0 2.9e-12 46.3 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HAMP PF00672.20 EXF77206.1 - 0.0042 17.2 4.5 0.078 13.1 0.0 3.2 3 0 0 3 3 3 1 HAMP domain IFT43 PF15305.1 EXF77207.1 - 0.058 13.4 1.3 0.12 12.3 0.9 1.6 1 0 0 1 1 1 0 Intraflagellar transport protein 43 Acetyltransf_1 PF00583.19 EXF77210.1 - 0.00045 20.2 0.0 0.00075 19.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF77210.1 - 0.0098 16.0 0.0 0.017 15.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Histone PF00125.19 EXF77211.1 - 9.2e-09 35.2 0.2 1.3e-08 34.8 0.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EXF77211.1 - 0.00075 19.5 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.1 EXF77211.1 - 0.093 12.9 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Kinetochore component CENP-S Svf1 PF08622.5 EXF77212.1 - 1.4e-128 428.5 0.0 1.7e-128 428.2 0.0 1.1 1 0 0 1 1 1 1 Svf1-like Ribosomal_L11_N PF03946.9 EXF77213.1 - 1.4e-25 88.5 0.1 3.1e-25 87.3 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EXF77213.1 - 4.2e-25 87.6 0.7 6.3e-25 87.1 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain BRCT PF00533.21 EXF77213.1 - 0.076 13.1 0.0 0.099 12.8 0.0 1.3 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain Pkinase PF00069.20 EXF77214.1 - 1.7e-57 194.5 0.0 3.7e-57 193.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Cpn10 PF00166.16 EXF77214.1 - 1.4e-25 89.0 0.0 3.1e-25 87.9 0.0 1.6 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Pkinase_Tyr PF07714.12 EXF77214.1 - 8e-21 74.2 0.0 1.4e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EXF77214.1 - 0.009 15.7 0.1 0.019 14.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EXF77214.1 - 0.21 10.5 0.0 0.35 9.8 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF3425 PF11905.3 EXF77216.1 - 3.4e-23 82.0 0.6 3.4e-23 82.0 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EXF77216.1 - 0.0093 15.9 18.7 0.25 11.3 12.9 2.2 1 1 0 1 1 1 1 bZIP transcription factor DUF904 PF06005.7 EXF77216.1 - 0.11 12.7 4.6 0.21 11.8 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Mnd1 PF03962.10 EXF77216.1 - 0.13 11.8 4.8 0.22 11.1 3.3 1.2 1 0 0 1 1 1 0 Mnd1 family DUF2962 PF11176.3 EXF77216.1 - 0.18 11.3 3.6 0.38 10.3 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2962) IncA PF04156.9 EXF77216.1 - 0.19 11.2 2.1 0.31 10.6 1.4 1.2 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 EXF77216.1 - 0.31 9.4 0.8 0.58 8.5 0.5 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF342) Lustrin_cystein PF14625.1 EXF77218.1 - 0.0085 16.1 6.1 0.0085 16.1 4.2 2.8 2 1 0 2 2 2 1 Lustrin, cysteine-rich repeated domain SOG2 PF10428.4 EXF77218.1 - 0.57 8.7 8.3 0.7 8.4 5.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Granulin PF00396.13 EXF77218.1 - 0.82 9.8 27.9 1.4 9.0 2.6 3.5 2 1 1 3 3 3 0 Granulin Dicty_REP PF05086.7 EXF77218.1 - 1.4 6.5 8.6 1.8 6.1 6.0 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF3132 PF11330.3 EXF77219.1 - 0.098 12.4 0.0 0.19 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3132) Methyltransf_23 PF13489.1 EXF77220.1 - 7.5e-09 35.5 0.0 1e-08 35.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF77220.1 - 6.2e-06 25.8 0.0 1.4e-05 24.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF77220.1 - 0.00019 21.9 0.0 0.00067 20.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF77220.1 - 0.0003 21.2 0.0 0.00053 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF77220.1 - 0.00062 20.1 0.0 0.0015 18.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF77220.1 - 0.00089 19.5 0.0 0.0015 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF77220.1 - 0.0029 16.7 0.0 0.0043 16.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EXF77220.1 - 0.01 15.8 0.0 0.032 14.2 0.0 1.8 2 1 0 2 2 2 0 Methyltransferase domain adh_short_C2 PF13561.1 EXF77221.1 - 1.4e-23 83.9 0.0 1.7e-23 83.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EXF77221.1 - 2.7e-23 82.7 4.2 4.1e-23 82.1 2.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF77221.1 - 1.2e-13 51.1 2.5 1.8e-13 50.5 1.7 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF77221.1 - 0.00068 19.1 0.1 0.00088 18.7 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EXF77221.1 - 0.081 11.8 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Fungal_trans PF04082.13 EXF77222.1 - 8.2e-64 214.9 0.0 1.1e-63 214.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EXF77222.1 - 9.5e-06 25.5 13.2 0.00029 20.9 0.7 3.9 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF77222.1 - 6e-05 23.1 12.9 0.00014 21.9 0.6 3.2 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EXF77222.1 - 0.0037 17.4 1.2 0.0037 17.4 0.8 3.1 3 0 0 3 3 3 2 Zinc-finger double domain F-box-like PF12937.2 EXF77223.1 - 1.3e-09 37.6 0.0 3.4e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EXF77223.1 - 1.9e-06 27.3 0.0 4.1e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like_2 PF13013.1 EXF77223.1 - 0.003 17.2 0.0 0.0062 16.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like domain SR-25 PF10500.4 EXF77223.1 - 0.62 9.5 9.9 0.9 8.9 6.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Mito_carr PF00153.22 EXF77224.1 - 4.7e-73 240.9 5.8 2.9e-25 87.7 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DnaJ PF00226.26 EXF77225.1 - 9.6e-24 82.9 2.2 9.6e-24 82.9 1.5 2.7 3 0 0 3 3 3 1 DnaJ domain TPR_11 PF13414.1 EXF77225.1 - 4e-20 71.2 6.9 4.2e-09 35.9 0.0 5.3 2 1 4 6 6 6 4 TPR repeat TPR_2 PF07719.12 EXF77225.1 - 2.5e-18 64.4 2.1 0.0057 16.4 0.0 8.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 EXF77225.1 - 7e-16 57.0 2.9 0.00017 21.0 0.0 6.3 7 0 0 7 7 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 EXF77225.1 - 1.5e-14 52.5 0.1 0.001 18.6 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 EXF77225.1 - 7.8e-14 50.9 4.6 0.024 15.2 0.0 7.6 2 2 6 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 EXF77225.1 - 1.4e-13 51.0 1.5 0.00068 20.2 0.0 5.1 4 1 0 5 5 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EXF77225.1 - 5.5e-10 39.0 2.0 0.0024 17.7 0.0 5.7 3 3 2 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EXF77225.1 - 5.2e-09 35.8 0.7 0.0038 17.0 0.0 4.3 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EXF77225.1 - 5.4e-08 32.7 8.1 1.1 9.8 0.0 7.3 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 EXF77225.1 - 1.8e-07 30.8 0.3 0.0073 16.4 0.1 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EXF77225.1 - 1.4e-06 28.5 8.9 0.35 11.2 0.2 4.5 2 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EXF77225.1 - 3.1e-06 26.5 5.1 2.4 8.1 0.0 6.5 5 1 1 6 6 6 2 Tetratricopeptide repeat Apc3 PF12895.2 EXF77225.1 - 5.1e-06 26.5 4.5 0.0028 17.7 0.0 4.2 3 2 2 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EXF77225.1 - 2.4e-05 23.5 5.6 2.9 6.8 0.1 5.4 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 EXF77225.1 - 0.31 11.1 4.8 1.7 8.8 0.0 4.1 3 1 1 5 5 4 0 Tetratricopeptide repeat Cob_adeno_trans PF01923.13 EXF77225.1 - 0.54 10.0 2.8 3.6 7.3 0.0 2.7 2 1 0 3 3 3 0 Cobalamin adenosyltransferase Enkurin PF13864.1 EXF77225.1 - 1.7 8.9 6.1 2.8 8.2 1.0 3.1 3 1 0 3 3 3 0 Calmodulin-binding COG2 PF06148.6 EXF77226.1 - 0.021 14.6 2.1 2.2 8.1 0.1 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Reo_sigmaC PF04582.7 EXF77226.1 - 0.057 12.5 0.7 0.7 9.0 0.0 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 EXF77226.1 - 0.095 10.5 1.6 0.32 8.7 0.2 1.9 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family DUF4618 PF15397.1 EXF77226.1 - 0.19 11.0 2.6 2.1 7.5 1.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) TMF_TATA_bd PF12325.3 EXF77226.1 - 0.51 10.0 0.1 0.51 10.0 0.0 2.7 3 1 0 3 3 3 0 TATA element modulatory factor 1 TATA binding PspB PF06667.7 EXF77226.1 - 1.6 8.7 5.6 4.5 7.2 0.1 3.8 2 1 1 3 3 3 0 Phage shock protein B Vac14_Fig4_bd PF11916.3 EXF77227.1 - 1.8e-62 209.7 14.6 2e-49 167.2 4.3 2.8 2 1 1 3 3 3 2 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EXF77227.1 - 2.8e-31 107.7 0.2 2e-23 82.5 0.0 4.9 4 1 1 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EXF77227.1 - 9.9e-09 34.5 3.5 0.00024 20.9 0.0 5.9 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.1 EXF77227.1 - 3e-08 33.9 5.3 3e-05 24.3 0.0 5.3 4 1 0 4 4 4 1 HEAT-like repeat HEAT_2 PF13646.1 EXF77227.1 - 4.6e-07 30.0 2.2 0.011 16.0 0.1 4.7 4 0 0 4 4 4 2 HEAT repeats Cnd1 PF12717.2 EXF77227.1 - 0.00038 20.3 0.5 2 8.2 0.0 3.5 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EXF77227.1 - 0.0014 18.3 0.0 0.47 10.3 0.0 4.3 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Arm_2 PF04826.8 EXF77227.1 - 0.048 12.7 0.0 0.72 8.9 0.0 2.4 2 0 0 2 2 2 0 Armadillo-like DUF3730 PF12530.3 EXF77227.1 - 0.14 12.0 4.3 3.9 7.3 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3730) FA_desaturase PF00487.19 EXF77230.1 - 7.6e-37 127.1 28.2 1.2e-36 126.5 19.6 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EXF77230.1 - 3.9e-11 42.5 0.2 1.8e-10 40.4 0.0 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_hydro_17 PF00332.13 EXF77231.1 - 7.9e-06 25.1 0.5 7.9e-06 25.1 0.3 2.2 2 1 1 3 3 3 1 Glycosyl hydrolases family 17 Aminotran_1_2 PF00155.16 EXF77232.1 - 1.3e-37 129.6 0.0 1.7e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EXF77232.1 - 0.00013 20.4 0.0 0.0003 19.2 0.0 1.5 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.15 EXF77232.1 - 0.017 13.7 0.0 0.5 8.8 0.0 2.6 2 1 0 2 2 2 0 Orn/Lys/Arg decarboxylase, major domain Glucan_synthase PF02364.10 EXF77233.1 - 0 1459.5 0.0 0 1458.5 0.0 1.5 1 0 0 1 1 1 1 1,3-beta-glucan synthase component FKS1_dom1 PF14288.1 EXF77233.1 - 2.8e-40 136.8 0.3 6.7e-40 135.6 0.2 1.7 1 0 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 SprT-like PF10263.4 EXF77234.1 - 2.8e-51 173.2 3.9 4.7e-51 172.5 2.7 1.4 1 0 0 1 1 1 1 SprT-like family HMG_box PF00505.14 EXF77234.1 - 5.8e-05 23.2 1.8 0.00014 22.0 0.1 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box YABBY PF04690.8 EXF77234.1 - 0.0072 16.5 0.4 0.035 14.3 0.3 2.2 1 0 0 1 1 1 1 YABBY protein Zn-ribbon_8 PF09723.5 EXF77234.1 - 0.12 12.4 2.1 0.28 11.1 1.5 1.6 1 0 0 1 1 1 0 Zinc ribbon domain Mog1 PF04603.7 EXF77235.1 - 4.3e-17 62.3 0.0 6.2e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Ran-interacting Mog1 protein HIT PF01230.18 EXF77236.1 - 1.5e-23 83.1 0.2 2.1e-23 82.6 0.1 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EXF77236.1 - 8.8e-15 54.9 0.0 1.3e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EXF77236.1 - 2.1e-05 24.1 0.3 3.3e-05 23.5 0.2 1.4 1 1 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CRAL_TRIO PF00650.15 EXF77237.1 - 4e-42 143.4 0.0 6.6e-42 142.7 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EXF77237.1 - 7.2e-17 61.2 0.0 2.6e-16 59.4 0.0 2.0 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EXF77237.1 - 3.7e-10 39.8 0.0 7.1e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DASH_Dam1 PF08653.5 EXF77238.1 - 2.3e-26 91.3 2.3 3.5e-26 90.7 1.6 1.3 1 0 0 1 1 1 1 DASH complex subunit Dam1 zf-C2H2_jaz PF12171.3 EXF77239.1 - 2.9e-09 36.8 0.2 5e-09 36.0 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EXF77239.1 - 0.025 14.4 0.1 0.05 13.5 0.1 1.5 1 1 0 1 1 1 0 C2H2-type zinc finger Spuma_A9PTase PF03539.9 EXF77239.1 - 0.075 12.9 0.1 0.096 12.5 0.0 1.2 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) zf-C2H2_2 PF12756.2 EXF77239.1 - 0.089 12.9 0.1 0.19 11.8 0.1 1.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Gaa1 PF04114.9 EXF77240.1 - 2.4e-99 333.3 1.1 3.9e-99 332.6 0.7 1.3 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component PCI PF01399.22 EXF77241.1 - 1.1e-10 41.7 0.0 2.1e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 PCI domain Spo0A_C PF08769.6 EXF77241.1 - 0.016 15.0 0.0 0.039 13.8 0.0 1.6 1 0 0 1 1 1 0 Sporulation initiation factor Spo0A C terminal NAD_binding_10 PF13460.1 EXF77242.1 - 2.9e-19 69.7 0.0 4.3e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EXF77242.1 - 4.6e-17 62.0 0.0 5.8e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EXF77242.1 - 9.8e-15 54.6 0.2 1.9e-14 53.6 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EXF77242.1 - 2.5e-11 42.8 0.1 7.9e-11 41.1 0.1 1.7 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EXF77242.1 - 1.3e-10 40.6 0.0 9e-09 34.6 0.0 2.3 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EXF77242.1 - 1.7e-05 23.8 0.6 0.0062 15.4 0.3 3.1 1 1 1 2 2 2 1 Male sterility protein KR PF08659.5 EXF77242.1 - 0.0014 18.3 0.0 1.4 8.5 0.0 2.3 2 0 0 2 2 2 2 KR domain adh_short PF00106.20 EXF77242.1 - 0.0019 18.1 0.0 0.036 13.9 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Saccharop_dh PF03435.13 EXF77242.1 - 0.0046 15.9 0.0 0.0069 15.4 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase HIM1 PF08732.5 EXF77242.1 - 0.0081 14.6 0.0 0.012 14.1 0.0 1.2 1 0 0 1 1 1 1 HIM1 Polysacc_synt_2 PF02719.10 EXF77242.1 - 0.022 13.6 0.0 0.049 12.5 0.0 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein ApbA PF02558.11 EXF77242.1 - 0.049 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DapB_N PF01113.15 EXF77242.1 - 0.11 12.4 0.1 0.31 10.9 0.0 1.8 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus DDE_Tnp_1_3 PF13612.1 EXF77242.1 - 0.12 12.0 0.0 0.41 10.3 0.0 1.7 2 0 0 2 2 2 0 Transposase DDE domain N6-adenineMlase PF10237.4 EXF77243.1 - 8.4e-54 181.6 0.0 8.3e-39 132.8 0.0 2.1 2 0 0 2 2 2 2 Probable N6-adenine methyltransferase UCH PF00443.24 EXF77244.1 - 6.9e-56 189.3 2.5 1.1e-55 188.6 1.8 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EXF77244.1 - 1.9e-32 112.8 0.8 2.8e-32 112.3 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EXF77244.1 - 2.4e-05 24.3 0.4 2.4e-05 24.3 0.2 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-ribbon_3 PF13248.1 EXF77244.1 - 0.071 12.3 2.9 18 4.7 0.0 3.7 3 1 0 3 3 3 0 zinc-ribbon domain zf-CCHC PF00098.18 EXF77244.1 - 4.8 7.3 8.8 57 3.9 0.1 4.3 4 0 0 4 4 4 0 Zinc knuckle Lactamase_B PF00753.22 EXF77245.1 - 1.5e-22 80.1 0.1 3.4e-22 79.0 0.1 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EXF77245.1 - 1.4e-05 24.7 0.0 2.4e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EXF77245.1 - 0.00012 21.8 0.1 0.00017 21.3 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Ytp1 PF10355.4 EXF77246.1 - 7.5e-113 376.2 5.3 1.1e-112 375.6 3.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EXF77246.1 - 7.4e-33 112.2 6.3 7.4e-33 112.2 4.3 3.5 3 0 0 3 3 3 2 Domain of unknown function (DUF2427) DUF3481 PF11980.3 EXF77246.1 - 0.57 10.0 0.1 0.57 10.0 0.0 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF3481) Rsa3 PF14615.1 EXF77247.1 - 4.4e-21 73.9 0.5 6.3e-21 73.3 0.3 1.3 1 0 0 1 1 1 1 Ribosome-assembly protein 3 RNA_polI_A34 PF08208.6 EXF77247.1 - 0.011 15.3 5.1 0.013 15.1 3.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 TBX PF12598.3 EXF77247.1 - 0.018 15.3 3.9 0.029 14.7 2.7 1.3 1 0 0 1 1 1 0 T-box transcription factor TATR PF03430.8 EXF77247.1 - 0.088 11.4 3.2 0.1 11.2 2.2 1.0 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF4157 PF13699.1 EXF77247.1 - 0.15 12.2 5.0 1.3 9.1 1.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4157) CFEM PF05730.6 EXF77248.1 - 2.5e-16 59.2 10.6 3.1e-16 58.9 7.3 1.1 1 0 0 1 1 1 1 CFEM domain TIL PF01826.12 EXF77248.1 - 4.5 7.4 6.9 2.2 8.4 3.3 1.5 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain CBS PF00571.23 EXF77249.1 - 5.3e-19 67.7 4.3 3.7e-05 23.4 0.1 5.6 5 1 0 5 5 5 5 CBS domain HEAT_2 PF13646.1 EXF77250.1 - 2e-23 82.4 14.8 2.5e-09 37.2 0.1 8.8 4 3 6 10 10 10 8 HEAT repeats HEAT PF02985.17 EXF77250.1 - 4.6e-23 79.1 17.6 0.0012 18.7 0.0 12.2 13 0 0 13 13 12 5 HEAT repeat HEAT_EZ PF13513.1 EXF77250.1 - 2.7e-19 69.0 24.2 9.6e-09 35.4 0.1 10.0 9 1 2 11 11 9 4 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EXF77250.1 - 1.2e-13 51.2 0.7 0.0072 16.6 0.1 8.1 6 2 4 10 10 8 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EXF77250.1 - 9.1e-09 34.9 0.5 0.00093 18.6 0.1 5.7 4 1 2 6 6 6 1 CLASP N terminal MMS19_C PF12460.3 EXF77250.1 - 8.5e-08 31.3 0.1 3.5e-06 26.0 0.1 3.2 2 1 1 3 3 3 1 RNAPII transcription regulator C-terminal RIX1 PF08167.7 EXF77250.1 - 5.4e-07 29.4 0.0 0.018 14.6 0.1 5.2 3 2 2 5 5 5 1 rRNA processing/ribosome biogenesis Proteasom_PSMB PF10508.4 EXF77250.1 - 5e-05 21.7 0.0 0.00044 18.6 0.0 2.5 2 0 0 2 2 2 1 Proteasome non-ATPase 26S subunit Cnd1 PF12717.2 EXF77250.1 - 0.0001 22.1 0.9 1.1 9.0 0.1 4.5 3 2 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 DUF4042 PF13251.1 EXF77250.1 - 0.00021 20.7 0.4 5.1 6.5 0.0 5.0 6 0 0 6 6 6 1 Domain of unknown function (DUF4042) Adaptin_N PF01602.15 EXF77250.1 - 0.00047 18.6 2.3 0.014 13.7 0.4 3.4 3 1 0 3 3 3 1 Adaptin N terminal region CAS_CSE1 PF03378.10 EXF77250.1 - 0.0023 16.2 0.0 2.4 6.3 0.0 3.1 2 0 0 2 2 2 2 CAS/CSE protein, C-terminus Arm PF00514.18 EXF77250.1 - 0.003 17.3 10.9 4 7.4 0.0 6.0 6 0 0 6 6 5 1 Armadillo/beta-catenin-like repeat DUF3554 PF12074.3 EXF77250.1 - 0.0035 16.8 0.1 0.64 9.3 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3554) TAN PF11640.3 EXF77250.1 - 0.0045 16.7 1.8 0.039 13.6 0.1 3.1 2 1 1 3 3 3 1 Telomere-length maintenance and DNA damage repair TFCD_C PF12612.3 EXF77250.1 - 0.0076 15.6 0.0 0.53 9.6 0.0 3.7 4 0 0 4 4 4 1 Tubulin folding cofactor D C terminal Cohesin_HEAT PF12765.2 EXF77250.1 - 0.0092 15.9 0.7 1 9.4 0.0 3.8 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion IBN_N PF03810.14 EXF77250.1 - 0.012 15.5 1.1 0.079 12.8 0.0 3.1 3 1 1 4 4 3 0 Importin-beta N-terminal domain DRIM PF07539.7 EXF77250.1 - 0.026 13.9 0.7 0.11 11.8 0.5 2.1 1 0 0 1 1 1 0 Down-regulated in metastasis Xpo1 PF08389.7 EXF77250.1 - 0.027 14.3 0.1 2.4 8.0 0.0 3.3 2 0 0 2 2 2 0 Exportin 1-like protein Telomere_reg-2 PF10193.4 EXF77250.1 - 0.064 13.5 0.6 0.28 11.4 0.4 2.2 1 0 0 1 1 1 0 Telomere length regulation protein V-ATPase_H_N PF03224.9 EXF77250.1 - 0.069 12.2 3.8 0.56 9.2 0.1 3.3 2 1 1 3 3 3 0 V-ATPase subunit H PAS_9 PF13426.1 EXF77252.1 - 3.2e-32 110.9 0.0 5.3e-18 65.3 0.0 3.5 3 0 0 3 3 3 3 PAS domain PAS_3 PF08447.6 EXF77252.1 - 7.7e-19 67.5 0.0 3.8e-11 42.9 0.0 3.6 3 0 0 3 3 3 3 PAS fold PAS PF00989.19 EXF77252.1 - 5.9e-16 58.2 0.0 7.7e-07 28.8 0.0 4.0 3 1 0 3 3 3 3 PAS fold GATA PF00320.22 EXF77252.1 - 3.2e-15 55.1 7.6 7.6e-15 53.9 5.2 1.6 1 0 0 1 1 1 1 GATA zinc finger PAS_4 PF08448.5 EXF77252.1 - 3.1e-09 36.8 0.0 0.0067 16.4 0.0 3.5 3 0 0 3 3 3 2 PAS fold PAS_11 PF14598.1 EXF77252.1 - 1.2e-08 34.9 0.5 0.0053 16.6 0.0 2.9 3 0 0 3 3 3 2 PAS domain RTA1 PF04479.8 EXF77253.1 - 1.1e-11 44.7 4.5 2.7e-11 43.4 3.1 1.6 1 1 0 1 1 1 1 RTA1 like protein Inp1 PF12634.2 EXF77254.1 - 2.6e-30 105.0 0.0 7e-30 103.6 0.0 1.7 1 0 0 1 1 1 1 Inheritance of peroxisomes protein 1 EI24 PF07264.6 EXF77255.1 - 2.4e-08 33.6 11.3 6.4e-07 29.0 7.9 2.2 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) Lumazine_bd_2 PF12893.2 EXF77255.1 - 0.016 15.7 0.1 0.038 14.5 0.1 1.5 1 0 0 1 1 1 0 Putative lumazine-binding FmdA_AmdA PF03069.10 EXF77256.1 - 2.1e-152 507.0 0.0 2.5e-152 506.8 0.0 1.0 1 0 0 1 1 1 1 Acetamidase/Formamidase family OTU PF02338.14 EXF77257.1 - 6.1e-13 49.4 0.0 9.7e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease Bromodomain PF00439.20 EXF77258.1 - 9.5e-39 131.2 2.9 1.9e-19 69.3 0.2 2.7 2 0 0 2 2 2 2 Bromodomain BAH PF01426.13 EXF77258.1 - 1.3e-15 57.2 0.5 4.1e-15 55.5 0.3 1.9 1 0 0 1 1 1 1 BAH domain Ribosomal_60s PF00428.14 EXF77258.1 - 0.0031 17.8 7.8 0.0031 17.8 5.4 4.7 4 1 0 4 4 4 1 60s Acidic ribosomal protein adh_short PF00106.20 EXF77260.1 - 1.6e-25 89.9 0.5 2.2e-25 89.5 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF77260.1 - 5.2e-21 75.5 0.7 6.5e-21 75.2 0.5 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF77260.1 - 5.5e-09 35.9 0.4 7.2e-09 35.5 0.2 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF77260.1 - 0.00012 21.5 0.4 0.00062 19.2 0.3 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EXF77260.1 - 0.00048 19.8 0.2 0.0012 18.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EXF77260.1 - 0.022 14.7 1.1 0.2 11.6 0.8 2.1 1 1 0 1 1 1 0 NADH(P)-binding DUF3403 PF11883.3 EXF77262.1 - 2.4 8.5 8.9 5.5 7.3 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF3403) Pyr_redox_2 PF07992.9 EXF77263.1 - 3e-19 69.6 0.1 3.9e-19 69.3 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF77263.1 - 4.4e-05 22.1 0.0 0.0032 15.9 0.0 2.2 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 EXF77263.1 - 9.9e-05 21.3 0.1 0.00062 18.7 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF77263.1 - 0.00011 22.1 0.0 0.00051 20.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EXF77263.1 - 0.00028 20.0 0.0 0.00047 19.3 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_2 PF00890.19 EXF77263.1 - 0.0003 19.7 0.1 0.0031 16.4 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain K_oxygenase PF13434.1 EXF77263.1 - 0.00031 19.7 0.0 0.26 10.1 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EXF77263.1 - 0.00046 20.2 0.0 0.031 14.3 0.0 2.4 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF77263.1 - 0.0022 17.7 0.3 0.12 12.1 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.17 EXF77263.1 - 0.0023 16.8 0.0 0.0041 16.0 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 EXF77263.1 - 0.0043 16.1 0.0 0.0084 15.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EXF77263.1 - 0.01 16.2 0.1 10 6.5 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF77263.1 - 0.028 13.3 0.3 0.048 12.5 0.0 1.5 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EXF77263.1 - 0.07 12.7 0.1 1.7 8.3 0.0 2.4 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_23 PF13489.1 EXF77264.1 - 1.1e-14 54.5 0.0 1.5e-14 54.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF77264.1 - 6.2e-13 48.5 0.0 8.3e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF77264.1 - 5.4e-12 46.0 0.0 1.1e-11 45.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF77264.1 - 4.9e-11 42.9 0.0 8.5e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF77264.1 - 5.1e-10 39.9 0.1 9.1e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF77264.1 - 6e-06 26.2 1.0 9.1e-06 25.6 0.2 1.6 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF77264.1 - 0.00014 21.0 0.0 0.0002 20.5 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 EXF77264.1 - 0.059 12.7 0.0 0.09 12.1 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) DREV PF05219.7 EXF77264.1 - 0.071 11.9 0.0 0.11 11.3 0.0 1.4 1 1 0 1 1 1 0 DREV methyltransferase Mito_carr PF00153.22 EXF77265.1 - 2.9e-49 164.7 2.6 3e-20 71.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2744 PF10910.3 EXF77266.1 - 0.07 12.9 0.1 0.2 11.4 0.0 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2744) HET PF06985.6 EXF77267.1 - 6.1e-29 100.9 0.3 3.3e-28 98.5 0.3 2.0 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) SNF2_N PF00176.18 EXF77268.1 - 5.7e-69 232.1 0.0 9e-69 231.5 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad54_N PF08658.5 EXF77268.1 - 9.3e-63 211.5 5.4 2.5e-62 210.1 3.5 1.9 2 0 0 2 2 2 1 Rad54 N terminal Helicase_C PF00271.26 EXF77268.1 - 1.1e-12 47.5 0.0 3.2e-12 46.1 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HDA2-3 PF11496.3 EXF77268.1 - 3.4e-05 22.7 0.0 0.00013 20.8 0.0 1.9 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.10 EXF77268.1 - 0.00054 19.8 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Citrate_ly_lig PF08218.6 EXF77268.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Citrate lyase ligase C-terminal domain UDP-g_GGTase PF06427.6 EXF77269.1 - 2.3e-59 200.2 0.0 1.6e-58 197.5 0.0 2.4 3 0 0 3 3 3 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EXF77269.1 - 1.8e-05 24.2 0.4 3.7e-05 23.1 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Coatomer_WDAD PF04053.9 EXF77270.1 - 3e-149 497.5 0.0 7.4e-149 496.3 0.0 1.7 3 0 0 3 3 3 1 Coatomer WD associated region COPI_C PF06957.6 EXF77270.1 - 4.9e-85 285.6 0.0 6.6e-85 285.1 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EXF77270.1 - 8.7e-50 164.9 9.5 2.4e-09 36.7 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat Nup160 PF11715.3 EXF77270.1 - 0.0063 14.7 7.9 0.28 9.2 0.1 3.8 2 1 1 4 4 4 2 Nucleoporin Nup120/160 Clathrin PF00637.15 EXF77270.1 - 0.011 15.3 0.7 0.077 12.5 0.0 2.3 2 0 0 2 2 2 0 Region in Clathrin and VPS SAC3_GANP PF03399.11 EXF77271.1 - 5.6e-20 71.7 0.0 3e-17 62.8 0.0 2.1 2 0 0 2 2 2 2 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EXF77271.1 - 1.3e-18 67.1 0.0 3.8e-09 36.4 0.0 2.2 2 0 0 2 2 2 2 COP9 signalosome, subunit CSN8 GSP_synth PF03738.9 EXF77273.1 - 1e-22 80.1 0.7 2.1e-22 79.2 0.1 1.8 2 0 0 2 2 2 1 Glutathionylspermidine synthase preATP-grasp Sel1 PF08238.7 EXF77275.1 - 2.2e-15 56.6 36.1 1.6e-07 31.7 0.2 7.8 8 0 0 8 8 8 5 Sel1 repeat TPR_1 PF00515.23 EXF77275.1 - 0.00046 19.6 0.2 0.0022 17.5 0.2 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EXF77275.1 - 0.014 14.9 0.6 0.014 14.9 0.4 2.7 2 1 0 2 2 2 0 TPR repeat TPR_8 PF13181.1 EXF77275.1 - 0.58 10.0 2.6 0.67 9.8 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Epimerase PF01370.16 EXF77276.1 - 7.2e-16 58.3 0.0 1.2e-15 57.6 0.0 1.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF77276.1 - 1.7e-10 41.1 0.1 8.1e-10 39.0 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EXF77276.1 - 7.9e-09 34.6 0.0 1.1e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EXF77276.1 - 6.8e-07 28.4 0.0 0.00069 18.6 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein adh_short PF00106.20 EXF77276.1 - 8.6e-07 29.0 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EXF77276.1 - 6.8e-06 25.4 0.0 1.7e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EXF77276.1 - 0.033 13.1 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Prominin PF05478.6 EXF77277.1 - 0.011 13.2 4.0 0.019 12.5 2.8 1.3 1 0 0 1 1 1 0 Prominin BEX PF04538.7 EXF77277.1 - 0.018 15.2 1.7 0.018 15.2 1.2 2.0 2 0 0 2 2 2 0 Brain expressed X-linked like family FBP PF07299.6 EXF77277.1 - 0.17 11.2 7.5 0.26 10.6 0.7 2.4 2 0 0 2 2 2 0 Fibronectin-binding protein (FBP) ParB PF08775.5 EXF77277.1 - 0.46 10.8 10.7 0.071 13.4 2.2 2.9 2 1 1 3 3 3 0 ParB family Herpes_BLLF1 PF05109.8 EXF77277.1 - 2.6 5.8 23.9 3.8 5.3 16.6 1.2 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Osmo_MPGsynth PF09488.5 EXF77278.1 - 4.9e-138 459.9 0.0 6.2e-138 459.6 0.0 1.0 1 0 0 1 1 1 1 Mannosyl-3-phosphoglycerate synthase (osmo_MPGsynth) CW_binding_2 PF04122.7 EXF77278.1 - 0.1 12.8 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 MFS_1 PF07690.11 EXF77279.1 - 9.2e-25 87.0 40.6 1.2e-24 86.7 28.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily AAA_12 PF13087.1 EXF77281.1 - 1.9e-41 141.6 0.0 2.9e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EXF77281.1 - 2.6e-25 89.3 0.0 7.9e-25 87.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain zf-CCCH PF00642.19 EXF77281.1 - 9.6e-09 34.7 3.8 2.3e-08 33.4 2.6 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA_19 PF13245.1 EXF77281.1 - 2.3e-08 33.6 0.0 7.9e-08 31.9 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EXF77281.1 - 5.9e-06 25.9 0.2 0.00077 19.0 0.0 2.7 3 0 0 3 3 3 1 AAA domain DUF2075 PF09848.4 EXF77281.1 - 6.5e-05 22.0 0.1 0.17 10.8 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.1 EXF77281.1 - 0.0006 19.8 0.1 0.003 17.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.13 EXF77281.1 - 0.00087 18.8 1.2 0.013 15.0 0.0 3.0 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.1 EXF77281.1 - 0.0032 17.5 0.0 0.01 15.9 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA PF00004.24 EXF77281.1 - 0.15 12.2 0.0 0.66 10.1 0.0 2.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) EI24 PF07264.6 EXF77283.1 - 1.1e-07 31.4 4.5 1.1e-07 31.4 3.1 2.2 2 0 0 2 2 2 1 Etoposide-induced protein 2.4 (EI24) PalH PF08733.5 EXF77283.1 - 0.12 11.1 2.2 0.2 10.4 1.6 1.2 1 0 0 1 1 1 0 PalH/RIM21 Fungal_trans PF04082.13 EXF77284.1 - 3e-09 36.1 0.0 6.3e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF77284.1 - 1.1e-06 28.4 9.1 1.1e-06 28.4 6.3 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SGL PF08450.7 EXF77285.1 - 3.6e-24 85.4 0.9 6.9e-24 84.5 0.6 1.5 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EXF77285.1 - 5.4e-06 26.3 0.0 2.6e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 Strictosidine synthase Arylesterase PF01731.15 EXF77285.1 - 0.0022 17.9 0.1 0.012 15.5 0.0 2.3 2 0 0 2 2 2 1 Arylesterase NHL PF01436.16 EXF77285.1 - 5.1 7.2 6.0 35 4.6 0.0 3.4 3 0 0 3 3 3 0 NHL repeat SDH_alpha PF03313.10 EXF77286.1 - 7e-90 300.8 0.1 1.1e-89 300.2 0.1 1.3 1 0 0 1 1 1 1 Serine dehydratase alpha chain SDH_beta PF03315.10 EXF77286.1 - 8.9e-51 172.0 0.0 1.7e-50 171.1 0.0 1.4 1 0 0 1 1 1 1 Serine dehydratase beta chain IDO PF01231.13 EXF77288.1 - 4.4e-15 55.0 0.0 8.9e-13 47.4 0.0 3.2 2 1 0 2 2 2 2 Indoleamine 2,3-dioxygenase Cyt-b5 PF00173.23 EXF77288.1 - 9.4e-14 50.9 0.0 1.9e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.16 EXF77288.1 - 0.0068 16.9 0.0 0.02 15.4 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain p450 PF00067.17 EXF77289.1 - 9.6e-67 225.4 0.0 1.3e-66 225.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Trp_DMAT PF11991.3 EXF77290.1 - 1.6e-65 221.7 0.0 2e-65 221.3 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Methyltransf_2 PF00891.13 EXF77291.1 - 1.4e-21 76.7 0.0 2.2e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EXF77291.1 - 0.0048 16.6 0.0 0.0083 15.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF77291.1 - 0.064 13.8 0.0 0.28 11.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain ABC2_membrane PF01061.19 EXF77292.1 - 3.7e-73 245.1 45.7 3.9e-38 130.7 12.0 2.7 3 0 0 3 3 3 2 ABC-2 type transporter PDR_CDR PF06422.7 EXF77292.1 - 3.1e-32 110.2 0.0 3.8e-28 97.1 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 EXF77292.1 - 1.4e-31 109.6 0.0 1.1e-15 58.1 0.0 3.0 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 EXF77292.1 - 1.4e-17 63.5 0.1 3.6e-17 62.2 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EXF77292.1 - 6.1e-10 38.6 30.1 8.3e-05 21.7 10.2 3.1 2 2 0 2 2 2 2 ABC-2 family transporter protein DUF258 PF03193.11 EXF77292.1 - 1.3e-07 30.9 0.0 3.9e-05 22.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 EXF77292.1 - 1.3e-07 31.5 0.1 0.0026 17.6 0.0 3.7 4 0 0 4 4 3 2 AAA domain AAA_25 PF13481.1 EXF77292.1 - 6.7e-07 28.8 0.1 0.00041 19.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EXF77292.1 - 7.2e-07 29.3 0.2 0.00048 20.1 0.1 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EXF77292.1 - 7.6e-06 25.3 0.4 0.0011 18.4 0.2 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 EXF77292.1 - 8.9e-05 21.9 0.2 0.0035 16.8 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EXF77292.1 - 0.0001 22.4 0.1 0.16 12.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EXF77292.1 - 0.00011 23.0 0.0 0.0035 18.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EXF77292.1 - 0.00025 20.3 0.0 0.12 11.6 0.0 2.9 3 1 1 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EXF77292.1 - 0.00051 20.3 0.0 0.0077 16.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EXF77292.1 - 0.00053 19.9 0.2 0.096 12.6 0.1 2.9 3 0 0 3 3 2 1 AAA domain NACHT PF05729.7 EXF77292.1 - 0.0012 18.4 1.2 0.31 10.6 0.1 3.2 3 0 0 3 3 3 1 NACHT domain UPF0079 PF02367.12 EXF77292.1 - 0.02 14.5 0.5 0.46 10.1 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA PF00004.24 EXF77292.1 - 0.025 14.7 0.1 3 8.0 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 EXF77292.1 - 0.03 14.2 0.2 0.38 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EXF77292.1 - 0.038 13.7 0.2 3.2 7.5 0.1 2.7 2 0 0 2 2 2 0 Part of AAA domain ArgK PF03308.11 EXF77292.1 - 0.041 12.6 0.1 2.4 6.8 0.0 2.8 3 0 0 3 3 3 0 ArgK protein AAA_23 PF13476.1 EXF77292.1 - 0.053 13.8 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EXF77292.1 - 0.092 13.2 0.2 21 5.6 0.1 3.1 3 1 0 3 3 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 EXF77292.1 - 0.093 12.1 0.3 3.6 6.9 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family AAA_30 PF13604.1 EXF77292.1 - 0.11 12.0 0.1 2 7.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EXF77292.1 - 0.13 12.4 0.0 26 5.0 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Viral_helicase1 PF01443.13 EXF77292.1 - 0.17 11.3 0.1 1.6 8.2 0.0 2.5 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase FAD_binding_3 PF01494.14 EXF77293.1 - 3.1e-57 194.2 0.0 1.1e-29 103.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EXF77293.1 - 4.8e-05 22.4 0.0 0.00066 18.6 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EXF77293.1 - 0.00039 19.5 0.0 0.00063 18.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EXF77293.1 - 0.00053 19.9 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EXF77293.1 - 0.028 14.5 0.0 0.087 12.8 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF77293.1 - 0.036 12.9 0.0 0.4 9.4 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.9 EXF77293.1 - 0.069 11.6 0.0 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein MFS_1 PF07690.11 EXF77295.1 - 3e-20 72.2 24.6 3e-20 72.2 17.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF77295.1 - 7e-16 57.8 26.3 1.5e-15 56.7 18.3 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter VirB8 PF04335.8 EXF77295.1 - 0.095 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 VirB8 protein PfkB PF00294.19 EXF77296.1 - 6.1e-11 42.0 0.0 1.2e-09 37.7 0.0 2.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase DUF3546 PF12066.3 EXF77298.1 - 7.7e-26 90.2 1.4 7.7e-26 90.2 1.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) DUF4187 PF13821.1 EXF77298.1 - 1.3e-24 85.5 0.1 3.1e-24 84.3 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) ARS2 PF04959.8 EXF77298.1 - 5.8e-06 26.6 3.5 1.9e-05 24.9 2.4 1.9 1 0 0 1 1 1 1 Arsenite-resistance protein 2 TspO_MBR PF03073.10 EXF77299.1 - 4.8e-40 136.4 6.5 5.9e-40 136.1 4.5 1.1 1 0 0 1 1 1 1 TspO/MBR family Mito_carr PF00153.22 EXF77300.1 - 2.4e-61 203.4 0.1 1.9e-21 75.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DEAD PF00270.24 EXF77301.1 - 1.7e-41 141.5 0.1 3e-40 137.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF77301.1 - 1.1e-26 92.4 0.2 2.6e-26 91.2 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PRAI PF00697.17 EXF77301.1 - 0.067 12.7 0.1 0.18 11.3 0.1 1.7 1 0 0 1 1 1 0 N-(5'phosphoribosyl)anthranilate (PRA) isomerase zf-CSL PF05207.8 EXF77303.1 - 2.3e-16 59.0 0.8 3.6e-16 58.4 0.5 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EXF77303.1 - 2.1e-14 52.9 0.1 3.8e-14 52.1 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain 14-3-3 PF00244.15 EXF77304.1 - 7.4e-116 385.2 3.0 8.6e-116 385.0 2.1 1.0 1 0 0 1 1 1 1 14-3-3 protein IATP PF04568.7 EXF77305.1 - 1.8e-21 76.0 1.3 2.1e-21 75.8 0.9 1.0 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP DUF489 PF04356.7 EXF77305.1 - 0.033 13.7 0.5 0.042 13.4 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF489) DUF3233 PF11557.3 EXF77305.1 - 0.037 12.8 0.0 0.04 12.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3233) NPV_P10 PF05531.7 EXF77305.1 - 0.11 12.8 1.0 0.15 12.3 0.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF1003 PF06210.6 EXF77305.1 - 0.55 10.1 2.5 0.84 9.5 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Nsp1_C PF05064.8 EXF77306.1 - 1.5e-39 134.2 1.3 3.4e-39 133.1 0.9 1.5 1 0 0 1 1 1 1 Nsp1-like C-terminal region Nucleoporin_FG PF13634.1 EXF77306.1 - 1.6e-25 89.5 246.9 7.4e-06 26.1 36.7 7.5 2 1 4 6 6 5 4 Nucleoporin FG repeat region DUF948 PF06103.6 EXF77306.1 - 0.04 13.7 1.5 0.23 11.3 0.1 2.3 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) TMCO5 PF14992.1 EXF77306.1 - 0.15 11.1 3.4 0.21 10.6 2.4 1.1 1 0 0 1 1 1 0 TMCO5 family GAS PF13851.1 EXF77306.1 - 0.28 10.3 4.6 3.7 6.7 0.0 2.2 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.4 EXF77306.1 - 0.29 10.9 5.7 0.3 10.9 3.1 1.5 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 EXF77306.1 - 0.41 10.9 1.3 3 8.1 0.0 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Tropomyosin PF00261.15 EXF77306.1 - 3.1 6.8 11.3 0.72 8.8 2.1 2.1 1 1 1 2 2 2 0 Tropomyosin APG6 PF04111.7 EXF77306.1 - 3.8 6.4 8.3 19 4.1 5.8 1.5 1 1 1 2 2 2 0 Autophagy protein Apg6 CENP-Q PF13094.1 EXF77306.1 - 4.4 7.3 8.5 56 3.7 5.9 2.2 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit BLOC1_2 PF10046.4 EXF77306.1 - 7.3 6.7 8.1 17 5.5 0.2 3.1 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nop14 PF04147.7 EXF77307.1 - 5.9 4.6 8.3 7.9 4.2 5.8 1.3 1 0 0 1 1 1 0 Nop14-like family GTP_EFTU PF00009.22 EXF77308.1 - 5.9e-38 130.1 0.0 1.2e-37 129.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EXF77308.1 - 3.5e-36 123.1 0.4 7.6e-36 122.0 0.3 1.6 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EXF77308.1 - 1e-10 41.5 0.2 2.2e-10 40.4 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EXF77308.1 - 0.0077 16.1 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EXF77308.1 - 0.18 11.5 1.8 0.43 10.3 0.2 2.5 3 1 0 3 3 3 0 Dynamin family DUF3329 PF11808.3 EXF77309.1 - 0.08 13.0 0.7 0.87 9.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3329) DUF202 PF02656.10 EXF77309.1 - 0.16 12.2 1.8 1.6 9.0 0.0 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF202) YjgP_YjgQ PF03739.9 EXF77309.1 - 0.42 9.3 3.9 1.1 7.8 0.1 2.1 1 1 1 2 2 2 0 Predicted permease YjgP/YjgQ family Fungal_trans_2 PF11951.3 EXF77310.1 - 3.2e-57 193.8 0.0 5.1e-57 193.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pro_isomerase PF00160.16 EXF77310.1 - 3.1e-50 170.3 0.2 7.2e-50 169.2 0.1 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EXF77310.1 - 1.1e-13 50.4 0.8 4.4e-08 32.7 0.0 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat Far-17a_AIG1 PF04750.9 EXF77311.1 - 2.1e-55 187.0 9.9 2.3e-55 186.8 6.8 1.0 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein DUF3185 PF11381.3 EXF77311.1 - 0.0036 17.0 1.8 0.0036 17.0 1.2 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF3185) ATP1G1_PLM_MAT8 PF02038.11 EXF77311.1 - 0.092 11.7 1.1 0.19 10.7 0.4 1.8 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family DAHP_synth_1 PF00793.15 EXF77312.1 - 8.2e-97 323.1 0.0 1e-96 322.8 0.0 1.1 1 0 0 1 1 1 1 DAHP synthetase I family Cytochrom_C1 PF02167.10 EXF77313.1 - 2.6e-81 272.4 0.0 3.1e-81 272.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EXF77313.1 - 0.0059 16.7 0.0 0.012 15.6 0.0 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EXF77313.1 - 0.17 12.7 0.4 0.51 11.2 0.1 2.1 2 1 0 2 2 2 0 Cytochrome c AAA PF00004.24 EXF77315.1 - 9.6e-41 139.0 0.0 1.7e-40 138.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EXF77315.1 - 4.3e-06 26.9 0.0 0.00059 19.9 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EXF77315.1 - 2.1e-05 24.2 0.1 0.00024 20.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EXF77315.1 - 0.00026 20.9 0.0 0.00071 19.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EXF77315.1 - 0.00028 20.9 0.0 0.0013 18.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 EXF77315.1 - 0.0019 17.1 0.0 0.0035 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EXF77315.1 - 0.0048 17.7 0.1 0.013 16.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EXF77315.1 - 0.0076 15.9 0.1 0.02 14.6 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EXF77315.1 - 0.0087 15.1 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EXF77315.1 - 0.019 14.9 0.1 0.045 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EXF77315.1 - 0.026 14.4 0.0 0.055 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EXF77315.1 - 0.036 13.9 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EXF77315.1 - 0.041 13.4 0.0 0.62 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EXF77315.1 - 0.047 13.8 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 EXF77315.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EXF77315.1 - 0.071 12.2 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin Sigma54_activ_2 PF14532.1 EXF77315.1 - 0.072 13.1 0.0 0.19 11.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EXF77315.1 - 0.11 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 EXF77315.1 - 0.13 11.9 0.6 11 5.6 0.0 2.7 2 1 1 3 3 3 0 Archaeal ATPase Mg_chelatase PF01078.16 EXF77315.1 - 0.13 11.3 0.0 0.31 10.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EXF77315.1 - 0.14 11.5 0.2 0.44 9.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain Cpn60_TCP1 PF00118.19 EXF77316.1 - 3.8e-137 457.8 14.1 4.7e-137 457.5 9.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_tail_X PF05489.7 EXF77316.1 - 0.007 15.8 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Phage Tail Protein X DUF3924 PF13062.1 EXF77316.1 - 0.036 13.9 0.1 4 7.3 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3924) AMP-binding PF00501.23 EXF77318.1 - 6.1e-78 262.0 0.0 1e-77 261.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EXF77318.1 - 3.2e-76 256.1 0.0 8.4e-76 254.8 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EXF77318.1 - 1.8e-52 178.6 0.8 4.3e-52 177.4 0.6 1.6 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EXF77318.1 - 1.2e-50 171.6 4.1 1.2e-50 171.6 2.9 2.8 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 EXF77318.1 - 6.3e-44 150.3 4.4 2.4e-43 148.3 3.0 2.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EXF77318.1 - 4.6e-43 147.0 4.3 4.6e-43 147.0 3.0 3.9 4 0 0 4 4 3 1 short chain dehydrogenase Condensation PF00668.15 EXF77318.1 - 7.5e-38 130.0 0.0 1.3e-37 129.2 0.0 1.4 1 0 0 1 1 1 1 Condensation domain Ketoacyl-synt_C PF02801.17 EXF77318.1 - 8.7e-28 96.5 0.0 2.4e-27 95.1 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EXF77318.1 - 1.5e-19 70.2 0.1 7.1e-18 64.9 0.0 3.1 3 0 0 3 3 2 1 Methyltransferase domain PP-binding PF00550.20 EXF77318.1 - 1.7e-17 63.4 0.0 1.9e-10 40.8 0.0 3.3 3 0 0 3 3 2 2 Phosphopantetheine attachment site NAD_binding_4 PF07993.7 EXF77318.1 - 2.6e-15 56.0 0.0 1.5e-14 53.5 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein Methyltransf_23 PF13489.1 EXF77318.1 - 7.1e-09 35.5 0.0 2.6e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF77318.1 - 7.8e-09 35.9 0.1 3.4e-08 33.8 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF77318.1 - 3e-08 34.2 0.3 4.5e-07 30.4 0.0 3.2 5 0 0 5 5 1 1 Methyltransferase domain Epimerase PF01370.16 EXF77318.1 - 3.3e-07 29.9 0.1 0.0033 16.8 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_31 PF13847.1 EXF77318.1 - 9.8e-07 28.4 0.0 2.7e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EXF77318.1 - 1e-05 24.6 0.1 2.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain 3Beta_HSD PF01073.14 EXF77318.1 - 6.7e-05 21.7 0.0 0.007 15.1 0.1 2.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family HxxPF_rpt PF13745.1 EXF77318.1 - 0.00019 21.6 0.0 0.0033 17.6 0.0 2.9 3 0 0 3 3 2 1 HxxPF-repeated domain AMP-binding_C PF13193.1 EXF77318.1 - 0.0089 16.9 0.2 15 6.6 0.0 3.5 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain adh_short_C2 PF13561.1 EXF77318.1 - 0.0093 15.7 0.0 1.6 8.4 0.0 2.7 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_16 PF10294.4 EXF77318.1 - 0.027 13.9 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 EXF77318.1 - 0.12 11.4 0.0 0.29 10.1 0.0 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Polysacc_synt_2 PF02719.10 EXF77318.1 - 0.15 10.9 1.5 0.41 9.4 0.1 2.2 3 0 0 3 3 3 0 Polysaccharide biosynthesis protein RrnaAD PF00398.15 EXF77318.1 - 0.91 8.4 0.0 2 7.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Myc_N PF01056.13 EXF77318.1 - 1 8.4 6.9 2.1 7.4 4.8 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Seryl_tRNA_N PF02403.17 EXF77318.1 - 1 9.3 2.8 5.5 7.0 0.6 2.3 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain p450 PF00067.17 EXF77319.1 - 1.4e-59 201.8 0.0 1.8e-59 201.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 EXF77320.1 - 1.7e-08 34.0 0.0 3e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF77320.1 - 2.7e-07 30.3 0.1 1.2e-05 25.0 0.0 2.6 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Methyltransf_24 PF13578.1 EXF77321.1 - 4.6e-06 27.4 0.0 8.4e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 EXF77321.1 - 0.00015 21.1 0.0 0.0002 20.7 0.0 1.2 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_18 PF12847.2 EXF77321.1 - 0.00075 20.0 0.0 0.002 18.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain p450 PF00067.17 EXF77322.1 - 1.2e-41 142.7 0.0 2.3e-41 141.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DUF2730 PF10805.3 EXF77322.1 - 0.095 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF2457 PF10446.4 EXF77323.1 - 3.1 6.4 21.3 0.11 11.2 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) BTV_NS2 PF04514.7 EXF77323.1 - 7.3 5.3 11.5 0.25 10.1 1.2 2.1 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 Pil1 PF13805.1 EXF77324.1 - 5.4e-109 363.5 4.9 6.7e-109 363.2 3.4 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 Alpha_GJ PF03229.8 EXF77325.1 - 0.0014 18.9 2.5 0.0014 18.9 1.7 2.2 2 0 0 2 2 2 1 Alphavirus glycoprotein J Tnp_DNA_bind PF14706.1 EXF77325.1 - 0.0089 15.7 0.4 5 6.9 0.1 3.5 4 0 0 4 4 4 2 Transposase DNA-binding Sod_Fe_C PF02777.13 EXF77326.1 - 1.4e-10 40.9 0.0 0.00016 21.4 0.0 2.3 2 0 0 2 2 2 2 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EXF77326.1 - 0.0026 18.0 0.0 0.004 17.3 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain MFS_1 PF07690.11 EXF77327.1 - 2.4e-28 98.8 29.7 4e-28 98.1 17.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF77327.1 - 9.5e-05 21.1 27.5 0.0049 15.4 19.1 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.3 EXF77327.1 - 3.2 6.1 32.5 0.0041 15.6 11.2 2.7 2 1 1 3 3 3 0 Vacuole effluxer Atg22 like Fungal_trans_2 PF11951.3 EXF77329.1 - 1.1e-25 90.0 9.8 1.6e-25 89.5 6.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF1147 PF06615.6 EXF77329.1 - 0.076 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) Aminotran_4 PF01063.14 EXF77330.1 - 1.3e-35 122.9 0.0 1.6e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV DUF2254 PF10011.4 EXF77330.1 - 0.06 11.8 0.0 0.069 11.6 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DAO PF01266.19 EXF77331.1 - 2.4e-16 59.5 0.1 3.3e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase PaaB PF06243.6 EXF77331.1 - 0.082 13.0 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Phenylacetic acid degradation B Aldo_ket_red PF00248.16 EXF77332.1 - 2.1e-65 220.3 0.0 3e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sugar_tr PF00083.19 EXF77333.1 - 1.5e-68 231.4 21.0 1.9e-68 231.1 14.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF77333.1 - 3.3e-13 49.0 42.3 2.9e-09 36.1 12.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3245 PF11595.3 EXF77334.1 - 0.62 10.3 3.8 14 5.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) Mito_carr PF00153.22 EXF77335.1 - 2.1e-71 235.6 1.1 1.4e-23 82.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.20 EXF77336.1 - 1.5e-63 214.3 0.0 2.2e-63 213.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF77336.1 - 1e-26 93.5 0.0 1.4e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF77336.1 - 0.00077 18.5 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EXF77336.1 - 0.058 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EXF77336.1 - 0.067 12.9 0.2 0.58 9.8 0.0 2.3 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.17 EXF77336.1 - 0.073 12.4 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 RIO1 family F-box PF00646.28 EXF77337.1 - 0.01 15.4 0.1 0.027 14.1 0.1 1.7 1 0 0 1 1 1 0 F-box domain Pkinase PF00069.20 EXF77338.1 - 4.3e-59 199.7 0.0 7.4e-59 199.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF77338.1 - 1.4e-32 112.8 0.0 5.3e-31 107.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF77338.1 - 6.1e-06 25.3 0.0 4.6e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like zf-MYND PF01753.13 EXF77338.1 - 0.00011 21.9 0.5 0.00022 21.0 0.4 1.4 1 0 0 1 1 1 1 MYND finger APH PF01636.18 EXF77338.1 - 0.00062 19.5 0.1 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Sybindin PF04099.7 EXF77339.1 - 4.9e-23 81.4 0.0 6.4e-23 81.0 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EXF77339.1 - 0.042 13.7 0.0 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 Sedlin, N-terminal conserved region Peroxin-3 PF04882.7 EXF77340.1 - 4.5e-146 486.9 0.0 5.2e-146 486.7 0.0 1.0 1 0 0 1 1 1 1 Peroxin-3 DUF1649 PF07855.7 EXF77341.1 - 6.4e-65 217.7 0.0 7.4e-65 217.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) Mo-co_dimer PF03404.11 EXF77341.1 - 0.083 12.5 0.1 0.12 11.9 0.1 1.2 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain Fork_head PF00250.13 EXF77342.1 - 3.4e-34 116.7 0.1 6.7e-34 115.7 0.1 1.4 1 0 0 1 1 1 1 Fork head domain DUF3316 PF11777.3 EXF77343.1 - 2.6 7.8 4.8 2 8.2 1.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3316) Pyridox_ox_2 PF12900.2 EXF77345.1 - 2e-35 121.7 0.0 1.9e-34 118.5 0.0 2.0 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Spermine_synth PF01564.12 EXF77346.1 - 6.9e-08 31.7 0.0 1.1e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 Spermine/spermidine synthase Methyltransf_23 PF13489.1 EXF77346.1 - 4.7e-05 23.1 0.0 0.00016 21.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF77346.1 - 9.2e-05 22.4 0.1 0.00019 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF77346.1 - 0.0055 17.2 0.0 0.0098 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MR_MLE_C PF13378.1 EXF77347.1 - 3.2e-19 68.9 0.0 1.1e-18 67.2 0.0 1.9 2 0 0 2 2 2 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EXF77347.1 - 1.9e-13 50.7 0.0 8.8e-13 48.5 0.0 2.0 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EXF77347.1 - 0.01 15.8 0.0 0.029 14.3 0.0 1.7 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.6 EXF77347.1 - 0.024 13.5 0.0 0.039 12.8 0.0 1.3 1 0 0 1 1 1 0 Methylaspartate ammonia-lyase C-terminus Rad10 PF03834.9 EXF77350.1 - 4.9e-31 106.2 0.0 7.7e-31 105.6 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EXF77350.1 - 0.00011 22.3 0.0 0.00028 21.0 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain Glyco_hydro_47 PF01532.15 EXF77351.1 - 2.2e-136 455.1 0.0 2.5e-136 454.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PepX_N PF09168.5 EXF77351.1 - 0.1 12.8 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 X-Prolyl dipeptidyl aminopeptidase PepX, N-terminal DNA_pol_alpha_N PF12254.3 EXF77352.1 - 0.034 13.9 0.1 0.06 13.1 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal XAP5 PF04921.9 EXF77352.1 - 0.084 12.4 0.6 0.099 12.1 0.4 1.0 1 0 0 1 1 1 0 XAP5, circadian clock regulator TT_ORF2 PF02957.10 EXF77352.1 - 0.15 12.8 2.8 0.18 12.5 2.0 1.1 1 0 0 1 1 1 0 TT viral ORF2 VIT1 PF01988.14 EXF77353.1 - 1.6e-57 194.4 5.2 2.1e-57 194.0 3.6 1.2 1 0 0 1 1 1 1 VIT family Fasciclin PF02469.17 EXF77354.1 - 1.1e-30 106.3 0.0 5.7e-16 58.6 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain EHN PF06441.7 EXF77356.1 - 1.2e-29 102.4 0.0 2.1e-29 101.6 0.0 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EXF77356.1 - 5.5e-08 32.9 0.2 8.2e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF77356.1 - 0.0089 15.6 0.8 0.072 12.6 0.2 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold HET PF06985.6 EXF77357.1 - 1.4e-23 83.6 0.0 2.4e-23 82.8 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DNA_ligase_aden PF01653.13 EXF77357.1 - 0.16 10.9 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain Lactamase_B_2 PF12706.2 EXF77358.1 - 1.4e-38 132.4 0.1 1.8e-38 132.0 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EXF77358.1 - 2.1e-08 34.0 0.0 3.2e-08 33.4 0.0 1.5 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EXF77358.1 - 0.0012 18.5 1.0 0.0036 16.9 0.2 2.1 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Ndc80_HEC PF03801.8 EXF77360.1 - 5.9e-63 211.0 0.3 5.9e-63 211.0 0.2 2.0 2 0 0 2 2 2 1 HEC/Ndc80p family ATG16 PF08614.6 EXF77360.1 - 0.0013 18.5 31.4 0.092 12.5 5.8 4.1 1 1 1 3 3 3 2 Autophagy protein 16 (ATG16) FliJ PF02050.11 EXF77360.1 - 0.0048 16.9 4.8 0.0048 16.9 3.3 3.7 3 1 1 4 4 4 2 Flagellar FliJ protein NPV_P10 PF05531.7 EXF77360.1 - 0.0065 16.6 8.4 0.89 9.8 0.5 4.0 2 1 1 3 3 3 2 Nucleopolyhedrovirus P10 protein Filament PF00038.16 EXF77360.1 - 0.017 14.6 44.1 0.043 13.2 9.1 3.2 3 1 0 3 3 3 0 Intermediate filament protein DUF1664 PF07889.7 EXF77360.1 - 0.022 14.5 1.1 0.022 14.5 0.8 5.5 3 2 3 6 6 6 0 Protein of unknown function (DUF1664) Anth_Ig PF05587.8 EXF77360.1 - 0.09 12.6 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Anthrax receptor extracellular domain WASH_WAHD PF11945.3 EXF77360.1 - 0.35 10.1 11.6 0.0087 15.3 3.0 1.8 2 0 0 2 2 2 0 WAHD domain of WASH complex APG6 PF04111.7 EXF77360.1 - 0.76 8.7 39.6 0.81 8.6 8.7 3.2 2 1 1 3 3 3 0 Autophagy protein Apg6 GAS PF13851.1 EXF77360.1 - 1.1 8.4 44.9 0.11 11.7 8.4 3.3 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 EXF77360.1 - 1.5 6.5 25.9 1.7 6.4 5.0 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF4391 PF14335.1 EXF77360.1 - 2.3 7.5 19.2 0.018 14.4 3.7 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4391) TPR_MLP1_2 PF07926.7 EXF77360.1 - 2.4 7.9 39.3 1.3 8.7 7.9 3.6 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Tropomyosin PF00261.15 EXF77360.1 - 3 6.8 47.2 0.5 9.4 8.4 3.4 2 1 1 3 3 3 0 Tropomyosin DivIC PF04977.10 EXF77360.1 - 7.5 6.1 27.6 0.88 9.1 0.1 5.3 3 2 2 5 5 5 0 Septum formation initiator Pex14_N PF04695.8 EXF77361.1 - 6.3e-38 129.9 0.2 6.3e-38 129.9 0.1 3.5 2 1 2 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-C4H2 PF10146.4 EXF77361.1 - 0.00028 20.9 6.8 0.00028 20.9 4.7 2.1 2 0 0 2 2 2 1 Zinc finger-containing protein ERM PF00769.14 EXF77361.1 - 0.0092 15.5 8.9 0.018 14.5 6.1 1.5 1 0 0 1 1 1 1 Ezrin/radixin/moesin family YPEB PF14620.1 EXF77361.1 - 0.015 14.3 2.8 0.025 13.5 1.9 1.4 1 0 0 1 1 1 0 YpeB sporulation CR6_interact PF10147.4 EXF77361.1 - 0.02 14.1 3.2 0.029 13.7 2.2 1.3 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 DUF244 PF03112.9 EXF77361.1 - 0.061 12.8 4.0 0.091 12.3 2.8 1.3 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF DUF3584 PF12128.3 EXF77361.1 - 0.064 10.5 9.2 0.092 10.0 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HLH PF00010.21 EXF77361.1 - 0.13 11.9 3.6 18 5.0 0.0 3.1 1 1 1 2 2 2 0 Helix-loop-helix DNA-binding domain DUF3811 PF11656.3 EXF77361.1 - 0.17 11.9 0.2 0.17 11.9 0.1 2.7 2 1 0 2 2 2 0 YjbD family (DUF3811) PilJ PF13675.1 EXF77361.1 - 0.19 12.0 6.1 0.065 13.5 1.5 2.3 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Baculo_PEP_C PF04513.7 EXF77361.1 - 0.24 11.2 8.8 2.4 7.9 1.5 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Orbi_VP5 PF00901.12 EXF77361.1 - 0.28 9.3 6.4 0.24 9.5 3.6 1.4 1 1 0 1 1 1 0 Orbivirus outer capsid protein VP5 Prominin PF05478.6 EXF77361.1 - 0.28 8.6 3.4 0.37 8.2 2.3 1.2 1 0 0 1 1 1 0 Prominin DUF1664 PF07889.7 EXF77361.1 - 0.88 9.3 5.3 0.73 9.6 1.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF848 PF05852.6 EXF77361.1 - 1.9 8.3 11.2 4 7.2 7.7 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) V_ATPase_I PF01496.14 EXF77361.1 - 3.4 5.3 4.9 4.7 4.9 3.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4404 PF14357.1 EXF77361.1 - 4.3 7.8 9.3 5 7.6 5.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) Abhydrolase_3 PF07859.8 EXF77362.1 - 7e-45 153.1 0.0 2.8e-44 151.2 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EXF77362.1 - 3.9e-05 22.4 0.1 0.00017 20.3 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EXF77362.1 - 0.00015 21.5 0.0 0.0011 18.7 0.0 2.1 2 1 0 3 3 3 1 Alpha/beta hydrolase family FAD_binding_4 PF01565.18 EXF77363.1 - 7.7e-15 54.5 0.0 1.3e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HMG_CoA_synt_C PF08540.5 EXF77364.1 - 1.2e-95 320.2 0.7 2.2e-95 319.3 0.5 1.4 1 1 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EXF77364.1 - 4.4e-93 309.6 0.4 6.3e-93 309.1 0.3 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal TPR_12 PF13424.1 EXF77365.1 - 1.4e-06 28.1 1.9 0.011 15.6 0.0 4.6 4 1 1 5 5 4 2 Tetratricopeptide repeat AAA_16 PF13191.1 EXF77365.1 - 3.8e-06 27.0 0.3 2.6e-05 24.2 0.0 2.7 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EXF77365.1 - 0.00027 21.0 0.3 0.0016 18.5 0.0 2.6 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EXF77365.1 - 0.00037 20.7 0.0 0.0028 17.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 EXF77365.1 - 0.00056 19.1 0.0 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 Chromatin associated protein KTI12 NACHT PF05729.7 EXF77365.1 - 0.0011 18.6 0.2 0.0031 17.2 0.1 1.8 1 0 0 1 1 1 1 NACHT domain IstB_IS21 PF01695.12 EXF77365.1 - 0.0067 15.8 0.0 0.024 14.0 0.0 1.9 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EXF77365.1 - 0.0087 15.7 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EXF77365.1 - 0.012 16.4 0.0 0.088 13.6 0.0 2.6 1 0 0 1 1 1 0 AAA domain DUF1967 PF09269.6 EXF77365.1 - 0.039 13.6 0.0 9.5 5.9 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Arch_ATPase PF01637.13 EXF77365.1 - 0.045 13.4 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Archaeal ATPase NTPase_1 PF03266.10 EXF77365.1 - 0.046 13.4 0.1 0.12 12.0 0.0 1.7 1 0 0 1 1 1 0 NTPase MMR_HSR1 PF01926.18 EXF77365.1 - 0.069 13.1 0.0 0.21 11.5 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.1 EXF77365.1 - 0.069 13.0 0.7 0.88 9.4 0.0 2.9 2 1 0 2 2 1 0 AAA domain AAA PF00004.24 EXF77365.1 - 0.072 13.2 0.1 0.32 11.1 0.0 2.3 2 1 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EXF77365.1 - 0.11 12.3 0.0 0.28 11.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPR_19 PF14559.1 EXF77365.1 - 0.28 11.5 11.4 0.55 10.6 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat BCS1_N PF08740.6 EXF77366.1 - 3.9e-55 186.3 2.8 6e-55 185.7 2.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EXF77366.1 - 5.8e-17 62.1 0.0 7.2e-08 32.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EXF77366.1 - 0.0014 18.4 0.0 0.011 15.4 0.0 2.6 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.1 EXF77366.1 - 0.0021 17.4 0.0 0.0053 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EXF77366.1 - 0.0029 17.6 0.7 0.02 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EXF77366.1 - 0.0036 16.3 0.0 0.0069 15.4 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EXF77366.1 - 0.004 17.9 0.8 0.015 16.1 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EXF77366.1 - 0.0045 16.6 0.0 0.017 14.8 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain KaiC PF06745.8 EXF77366.1 - 0.026 13.6 0.0 0.062 12.4 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_18 PF13238.1 EXF77366.1 - 0.031 14.5 0.5 0.3 11.3 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EXF77366.1 - 0.059 12.9 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.12 EXF77366.1 - 0.071 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2178 PF09946.4 EXF77366.1 - 0.12 12.0 0.0 0.28 10.9 0.0 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) CCDC92 PF14916.1 EXF77368.1 - 0.036 13.6 0.0 0.07 12.7 0.0 1.5 1 0 0 1 1 1 0 Coiled-coil domain of unknown function HALZ PF02183.13 EXF77368.1 - 0.074 12.7 0.0 0.47 10.2 0.0 2.1 2 0 0 2 2 2 0 Homeobox associated leucine zipper PS_Dcarbxylase PF02666.10 EXF77369.1 - 8.9e-53 178.5 0.0 1.5e-52 177.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EXF77369.1 - 1.2e-33 114.8 0.7 2.8e-16 59.1 0.0 2.7 2 0 0 2 2 2 2 C2 domain EF-hand_5 PF13202.1 EXF77369.1 - 0.0012 18.1 0.0 0.026 13.8 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EXF77369.1 - 0.0041 17.2 0.2 0.013 15.6 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EXF77369.1 - 0.0056 15.8 0.0 0.027 13.7 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EXF77369.1 - 0.02 14.7 0.1 0.12 12.3 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain CEP76-C2 PF15627.1 EXF77369.1 - 0.12 11.9 0.0 0.52 9.8 0.0 2.1 2 0 0 2 2 2 0 CEP76 C2 domain DUF1996 PF09362.5 EXF77370.1 - 1.1e-50 172.4 0.4 1.4e-50 172.2 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) LRR_4 PF12799.2 EXF77371.1 - 0.0058 16.2 4.9 0.21 11.2 0.0 4.3 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) SAPS PF04499.10 EXF77371.1 - 0.22 10.1 3.1 0.38 9.3 2.2 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ribosomal_L18p PF00861.17 EXF77374.1 - 5e-40 136.4 0.1 5e-40 136.4 0.1 1.8 2 0 0 2 2 2 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EXF77374.1 - 2.7e-33 114.3 12.0 2.7e-33 114.3 8.3 1.7 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Uteroglobin PF01099.12 EXF77374.1 - 5.4 6.8 7.4 2.5 7.9 0.1 2.7 2 1 1 3 3 3 0 Uteroglobin family HAD_2 PF13419.1 EXF77375.1 - 6.9e-15 55.7 0.0 5.4e-14 52.7 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EXF77375.1 - 0.0091 15.6 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Methyltransf_31 PF13847.1 EXF77376.1 - 5.4e-19 68.2 0.0 1.1e-18 67.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF77376.1 - 1e-16 61.1 0.1 1.6e-14 54.1 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF77376.1 - 2.9e-15 56.8 0.1 2.1e-13 50.8 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF77376.1 - 2.6e-14 52.8 0.0 4.6e-14 52.1 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EXF77376.1 - 1.2e-13 51.3 0.0 2e-12 47.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF77376.1 - 7.3e-12 45.5 0.0 2.7e-10 40.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF77376.1 - 1.5e-09 37.7 0.0 3.7e-09 36.5 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF77376.1 - 9.4e-09 35.3 0.0 2.2e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EXF77376.1 - 3.3e-07 30.0 0.0 6.9e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TPMT PF05724.6 EXF77376.1 - 0.0001 21.8 0.0 0.00016 21.1 0.0 1.3 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) UPF0020 PF01170.13 EXF77376.1 - 0.0046 16.5 0.0 0.0091 15.5 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_24 PF13578.1 EXF77376.1 - 0.027 15.2 0.0 0.093 13.5 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain CMAS PF02353.15 EXF77376.1 - 0.029 13.4 0.0 0.2 10.7 0.0 2.0 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase CheR PF01739.13 EXF77376.1 - 0.041 13.1 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain Fibrillarin PF01269.12 EXF77376.1 - 0.1 11.5 0.0 0.21 10.4 0.0 1.4 1 1 0 1 1 1 0 Fibrillarin Spt5_N PF11942.3 EXF77377.1 - 0.19 12.3 7.4 0.53 10.9 5.1 1.7 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CENP-B_dimeris PF09026.5 EXF77377.1 - 0.78 10.0 5.8 1.7 8.9 4.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CAP59_mtransfer PF11735.3 EXF77378.1 - 5.2e-62 209.2 0.0 7e-62 208.8 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 Fork_head PF00250.13 EXF77379.1 - 1.3e-11 44.3 0.0 2.8e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Fork head domain FHA PF00498.21 EXF77379.1 - 0.00014 21.9 0.0 0.00027 20.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain DUF2320 PF10082.4 EXF77379.1 - 0.033 12.9 1.9 0.055 12.1 1.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2320) Sulfate_transp PF00916.15 EXF77380.1 - 1.3e-05 24.3 10.0 1.3e-05 24.3 6.9 2.1 1 1 1 2 2 2 1 Sulfate transporter family Epiglycanin_C PF14654.1 EXF77381.1 - 0.042 13.8 0.2 0.81 9.7 0.0 2.5 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Col_cuticle_N PF01484.12 EXF77381.1 - 0.28 10.9 1.9 0.62 9.7 1.3 1.5 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain PAT1 PF09770.4 EXF77382.1 - 0.023 12.9 9.5 0.027 12.7 6.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TatD_DNase PF01026.16 EXF77383.1 - 6.6e-32 110.6 0.0 1e-31 110.1 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase NPP1 PF05630.6 EXF77384.1 - 9.1e-64 214.9 0.0 1e-63 214.7 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Na_Ca_ex PF01699.19 EXF77385.1 - 7.2e-28 96.9 24.0 1.4e-14 53.8 2.2 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Equine_IAV_S2 PF06502.6 EXF77385.1 - 0.13 12.1 0.1 0.59 10.0 0.0 2.0 2 0 0 2 2 2 0 Equine infectious anaemia virus S2 protein C2 PF00168.25 EXF77387.1 - 1.9e-10 40.4 0.1 3.5e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain zf-C2H2 PF00096.21 EXF77388.1 - 0.018 15.3 0.7 0.069 13.5 0.5 2.1 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF77388.1 - 0.096 13.0 0.6 0.096 13.0 0.4 2.0 2 0 0 2 2 2 0 C2H2-type zinc finger NTPase_I-T PF01931.13 EXF77389.1 - 9e-53 178.4 0.0 1e-52 178.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 Evr1_Alr PF04777.8 EXF77390.1 - 2e-26 91.7 0.1 2.7e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 Erv1 / Alr family Toxin-deaminase PF14424.1 EXF77390.1 - 0.11 12.5 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 The BURPS668_1122 family of deaminases Proteasome PF00227.21 EXF77391.1 - 2.7e-48 163.8 0.2 3.2e-48 163.5 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Cyclin PF08613.6 EXF77393.1 - 4.3e-39 134.2 1.5 8.6e-23 81.4 0.0 2.6 2 0 0 2 2 2 2 Cyclin PBP1_TM PF14812.1 EXF77393.1 - 0.24 11.7 3.8 0.69 10.2 2.6 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyoxalase_2 PF12681.2 EXF77394.1 - 3.8e-07 30.6 0.0 4.7e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EXF77394.1 - 0.007 16.3 0.1 0.023 14.6 0.1 1.8 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily MFS_1 PF07690.11 EXF77395.1 - 3.1e-28 98.5 69.1 1.9e-18 66.3 24.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Pheromone PF08015.6 EXF77395.1 - 0.24 12.2 2.5 0.5 11.2 1.7 1.6 1 0 0 1 1 1 0 Fungal mating-type pheromone S-methyl_trans PF02574.11 EXF77396.1 - 3.5e-23 82.3 0.0 4.4e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Homocysteine S-methyltransferase BNR_2 PF13088.1 EXF77398.1 - 0.0032 16.8 0.1 0.011 14.9 0.0 1.8 1 1 1 2 2 2 1 BNR repeat-like domain His_Phos_2 PF00328.17 EXF77399.1 - 6.5e-29 101.3 0.0 9.9e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EXF77399.1 - 0.0052 16.8 0.0 0.01 15.9 0.0 1.5 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) UFD1 PF03152.9 EXF77401.1 - 7.9e-25 86.9 0.0 2.4e-20 72.3 0.0 3.2 3 1 0 3 3 3 2 Ubiquitin fusion degradation protein UFD1 UBA PF00627.26 EXF77401.1 - 0.011 15.5 0.1 0.056 13.3 0.1 2.1 2 0 0 2 2 2 0 UBA/TS-N domain PRP21_like_P PF12230.3 EXF77401.1 - 0.1 12.0 0.3 0.46 9.9 0.1 2.0 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein Ribosomal_S15 PF00312.17 EXF77401.1 - 0.18 11.5 0.0 6.6 6.5 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S15 F-box PF00646.28 EXF77402.1 - 0.07 12.8 0.1 0.21 11.2 0.1 1.8 1 1 1 2 2 2 0 F-box domain Cupin_1 PF00190.17 EXF77403.1 - 2.3e-13 49.8 0.1 3e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EXF77403.1 - 1.2e-05 24.6 0.0 2e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Actin PF00022.14 EXF77404.1 - 1.3e-99 333.3 0.0 1.5e-99 333.1 0.0 1.0 1 0 0 1 1 1 1 Actin Aldo_ket_red PF00248.16 EXF77406.1 - 3.2e-56 190.2 0.0 3.9e-56 189.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Sugar_tr PF00083.19 EXF77409.1 - 2.7e-85 286.6 20.7 3.1e-85 286.4 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF77409.1 - 3.8e-25 88.3 38.9 5.4e-16 58.2 13.3 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2 PF00096.21 EXF77410.1 - 0.015 15.5 0.7 0.015 15.5 0.5 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF77410.1 - 0.023 15.0 7.4 0.037 14.3 0.2 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EXF77410.1 - 0.04 13.8 2.1 0.11 12.4 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zf-met PF12874.2 EXF77410.1 - 0.076 13.2 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of C2H2 type RhgB_N PF09284.5 EXF77411.1 - 4.8e-108 360.2 6.7 7.2e-108 359.6 4.7 1.3 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 EXF77411.1 - 2.1e-59 199.9 0.1 5.8e-59 198.4 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EXF77411.1 - 9.7e-19 67.2 2.6 2.4e-18 66.0 1.8 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EXF77411.1 - 9.9e-05 22.3 1.1 9.9e-05 22.3 0.8 3.9 4 1 1 5 5 5 1 Carboxypeptidase regulatory-like domain DUF3823 PF12866.2 EXF77411.1 - 0.024 14.1 0.1 0.049 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3823) FAD_binding_3 PF01494.14 EXF77414.1 - 4.3e-19 68.7 0.0 6.1e-19 68.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF77414.1 - 6.6e-12 44.9 0.1 2.6e-05 23.3 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EXF77414.1 - 5.2e-08 33.1 0.1 0.00013 22.3 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF77414.1 - 0.00059 19.8 0.2 0.0015 18.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF77414.1 - 0.0095 15.8 0.1 0.019 14.8 0.1 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EXF77414.1 - 0.018 14.1 0.0 0.25 10.3 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase ApbA PF02558.11 EXF77414.1 - 0.049 13.0 0.2 0.098 12.1 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_2 PF00890.19 EXF77414.1 - 0.095 11.5 0.3 0.17 10.6 0.2 1.6 2 0 0 2 2 2 0 FAD binding domain GrpB PF04229.9 EXF77415.1 - 1.9e-48 164.3 0.0 2.2e-48 164.1 0.0 1.0 1 0 0 1 1 1 1 GrpB protein NTP_transf_5 PF14907.1 EXF77415.1 - 0.08 12.2 0.1 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised nucleotidyltransferase GCIP PF13324.1 EXF77417.1 - 1.1e-06 28.0 5.0 2.4e-06 27.0 2.9 1.9 2 1 0 2 2 2 1 Grap2 and cyclin-D-interacting SGT1 PF07093.6 EXF77417.1 - 0.00049 18.6 1.5 0.00063 18.2 1.0 1.4 1 0 0 1 1 1 1 SGT1 protein Sigma70_ner PF04546.8 EXF77417.1 - 0.0012 18.4 8.0 0.0025 17.4 5.5 1.5 1 0 0 1 1 1 1 Sigma-70, non-essential region DUF2457 PF10446.4 EXF77417.1 - 0.017 13.8 25.6 0.026 13.2 17.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RXT2_N PF08595.6 EXF77417.1 - 0.027 14.2 5.9 0.055 13.2 4.1 1.6 1 0 0 1 1 1 0 RXT2-like, N-terminal DUF506 PF04720.7 EXF77417.1 - 0.14 11.8 1.1 0.2 11.2 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF506) Daxx PF03344.10 EXF77417.1 - 0.16 10.4 10.2 0.2 10.0 7.1 1.1 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EXF77417.1 - 0.21 9.5 9.2 0.29 9.1 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein eIF-3c_N PF05470.7 EXF77417.1 - 0.27 9.2 3.9 0.37 8.8 2.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CobT PF06213.7 EXF77417.1 - 0.31 10.1 18.8 0.5 9.4 13.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4484 PF14831.1 EXF77417.1 - 0.32 11.0 7.1 0.59 10.2 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) RRN3 PF05327.6 EXF77417.1 - 0.43 8.6 9.8 0.66 8.0 6.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Vfa1 PF08432.5 EXF77417.1 - 0.51 10.3 5.2 0.92 9.4 3.6 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.7 EXF77417.1 - 0.78 7.5 14.7 1.1 7.0 10.2 1.1 1 0 0 1 1 1 0 Nop14-like family Nop25 PF09805.4 EXF77417.1 - 1.2 9.2 8.7 2.2 8.3 6.0 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) PRKCSH-like PF12999.2 EXF77418.1 - 2.5e-42 144.3 5.3 1.1e-23 83.7 0.4 2.7 3 0 0 3 3 2 2 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EXF77418.1 - 6.8e-31 106.8 4.8 4.1e-30 104.2 0.5 2.6 3 0 0 3 3 3 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.8 EXF77418.1 - 1.9e-10 41.3 0.7 1.9e-10 41.3 0.5 2.3 3 0 0 3 3 1 1 Glucosidase II beta subunit-like protein Snapin_Pallidin PF14712.1 EXF77418.1 - 0.0037 17.5 3.5 0.019 15.2 0.0 2.6 2 0 0 2 2 2 1 Snapin/Pallidin IncA PF04156.9 EXF77418.1 - 0.0089 15.6 15.8 0.026 14.0 4.1 3.0 3 0 0 3 3 3 1 IncA protein NPV_P10 PF05531.7 EXF77418.1 - 0.0099 16.1 2.5 1.1 9.5 0.0 2.6 3 0 0 3 3 2 1 Nucleopolyhedrovirus P10 protein PilJ PF13675.1 EXF77418.1 - 0.029 14.6 2.3 1.8 8.9 0.2 3.0 3 0 0 3 3 3 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4559 PF15112.1 EXF77418.1 - 0.038 13.1 2.6 0.076 12.1 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) DUF3086 PF11285.3 EXF77418.1 - 0.043 12.6 5.8 0.2 10.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3086) OmpH PF03938.9 EXF77418.1 - 0.088 12.7 3.2 1.8 8.4 0.6 2.6 2 1 0 2 2 2 0 Outer membrane protein (OmpH-like) Prominin PF05478.6 EXF77418.1 - 0.099 10.1 0.2 0.14 9.6 0.1 1.2 1 0 0 1 1 1 0 Prominin TPR_MLP1_2 PF07926.7 EXF77418.1 - 0.3 10.8 18.1 4.1 7.1 0.7 3.2 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4047 PF13256.1 EXF77418.1 - 0.3 11.0 0.1 0.3 11.0 0.0 2.3 3 0 0 3 3 2 0 Domain of unknown function (DUF4047) DUF4407 PF14362.1 EXF77418.1 - 0.39 9.6 7.9 0.14 11.1 2.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) ATG16 PF08614.6 EXF77418.1 - 0.43 10.3 13.9 2.5 7.8 2.9 3.1 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.5 EXF77418.1 - 0.44 10.6 3.3 15 5.6 0.0 3.0 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family Lectin_N PF03954.9 EXF77418.1 - 0.91 8.9 2.5 3.9 6.8 0.4 2.2 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF641 PF04859.7 EXF77418.1 - 1.2 8.8 7.7 14 5.3 3.1 2.5 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) DivIC PF04977.10 EXF77418.1 - 1.3 8.5 20.9 2 7.9 0.4 4.3 3 1 1 4 4 4 0 Septum formation initiator Syntaxin-6_N PF09177.6 EXF77418.1 - 2.2 8.7 7.2 29 5.1 1.1 3.3 3 0 0 3 3 3 0 Syntaxin 6, N-terminal DUF4200 PF13863.1 EXF77418.1 - 2.3 8.1 22.8 0.75 9.7 6.9 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) NuA4 PF09340.5 EXF77418.1 - 3 7.5 9.0 9.5 5.9 0.0 3.7 3 1 0 3 3 3 0 Histone acetyltransferase subunit NuA4 GAS PF13851.1 EXF77418.1 - 5 6.2 15.6 0.55 9.3 3.0 3.0 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.7 EXF77418.1 - 6.1 6.6 8.1 2.3 8.0 1.0 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF1664) TMF_TATA_bd PF12325.3 EXF77418.1 - 6.6 6.4 13.9 12 5.6 7.3 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding BLOC1_2 PF10046.4 EXF77418.1 - 6.8 6.9 9.7 1.2 9.2 0.7 2.8 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Rtf2 PF04641.7 EXF77419.1 - 5.3e-54 183.1 1.4 6.5e-54 182.8 1.0 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 EXF77419.1 - 4.5e-05 23.0 0.6 0.00027 20.5 0.0 2.6 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EXF77419.1 - 0.0095 15.5 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EXF77419.1 - 0.01 15.6 0.1 0.027 14.3 0.1 1.6 1 1 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 EXF77419.1 - 0.012 15.3 0.1 0.019 14.6 0.1 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-Nse PF11789.3 EXF77419.1 - 0.05 13.1 0.2 0.15 11.5 0.2 1.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 EXF77419.1 - 0.083 12.5 0.2 0.15 11.7 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EXF77419.1 - 0.11 12.5 0.2 0.26 11.3 0.1 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vfa1 PF08432.5 EXF77419.1 - 3.7 7.5 10.7 5.7 6.9 7.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 FAT PF02259.18 EXF77420.1 - 1.1e-127 425.8 7.3 2.3e-127 424.7 5.0 1.6 1 0 0 1 1 1 1 FAT domain DUF3385 PF11865.3 EXF77420.1 - 1.2e-62 210.5 0.3 1.7e-60 203.5 0.1 3.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 EXF77420.1 - 2.9e-62 210.2 0.3 5.6e-62 209.2 0.2 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 EXF77420.1 - 1e-43 147.4 0.3 1e-43 147.4 0.2 3.1 3 0 0 3 3 3 1 Rapamycin binding domain HEAT_2 PF13646.1 EXF77420.1 - 1.2e-17 63.9 14.5 0.00016 21.9 0.4 9.0 6 3 3 9 9 9 5 HEAT repeats FATC PF02260.15 EXF77420.1 - 1.7e-14 52.9 0.1 4e-14 51.7 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 EXF77420.1 - 1.3e-13 49.7 21.1 0.002 18.0 0.0 11.3 11 0 0 11 11 11 2 HEAT repeat HEAT_EZ PF13513.1 EXF77420.1 - 1.7e-10 41.0 21.7 0.00019 21.7 0.2 11.9 11 2 2 13 13 12 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EXF77420.1 - 1.3e-05 25.5 0.8 1.1e+02 3.2 0.0 7.6 7 2 1 8 8 7 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EXF77420.1 - 2.5e-05 22.8 10.5 0.0048 15.2 0.1 4.1 4 0 0 4 4 4 3 Adaptin N terminal region Baculo_PEP_C PF04513.7 EXF77420.1 - 0.00021 21.1 0.9 0.0023 17.7 0.1 3.2 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus Beta-lactamase PF00144.19 EXF77421.1 - 2.3e-37 128.7 0.3 3.6e-37 128.1 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase Ribosomal_L11_N PF03946.9 EXF77421.1 - 0.1 12.0 0.4 0.22 11.0 0.3 1.5 1 0 0 1 1 1 0 Ribosomal protein L11, N-terminal domain Fungal_trans_2 PF11951.3 EXF77422.1 - 7e-09 34.7 0.1 2.7e-08 32.8 0.1 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF77422.1 - 3.6e-06 26.7 3.8 8.3e-06 25.6 2.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CVNH PF08881.5 EXF77423.1 - 1.1e-08 35.2 0.0 1.3e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 CVNH domain N_methyl_3 PF13633.1 EXF77423.1 - 0.22 11.5 2.2 0.34 10.8 1.5 1.3 1 0 0 1 1 1 0 Prokaryotic N-terminal methylation site DAO PF01266.19 EXF77424.1 - 1.7e-28 99.6 0.7 2.6e-28 98.9 0.5 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EXF77424.1 - 3.4e-05 23.6 0.1 0.00011 22.0 0.0 1.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EXF77424.1 - 4.8e-05 23.4 0.1 0.42 10.6 0.0 2.4 1 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF77424.1 - 0.00011 22.1 0.1 0.00036 20.4 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EXF77424.1 - 0.0018 17.2 0.0 0.0028 16.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EXF77424.1 - 0.0037 16.3 0.0 0.0067 15.5 0.0 1.3 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.1 EXF77424.1 - 0.0055 15.6 0.0 0.04 12.8 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EXF77424.1 - 0.0061 16.4 0.0 0.013 15.3 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 EXF77425.1 - 1.3e-07 30.6 27.8 1.3e-07 30.6 19.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EXF77425.1 - 1.3e-06 28.0 2.4 1.3e-06 28.0 1.6 2.4 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 CD34_antigen PF06365.7 EXF77426.1 - 0.3 10.7 0.2 0.3 10.7 0.1 2.0 2 0 0 2 2 2 0 CD34/Podocalyxin family DUF2061 PF09834.4 EXF77426.1 - 1.8 8.8 5.1 2.9 8.1 0.2 2.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2061) Sugar_tr PF00083.19 EXF77427.1 - 6.3e-70 235.9 23.0 7.6e-70 235.7 15.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF77427.1 - 1.2e-15 57.0 22.1 1.2e-15 57.0 15.3 2.1 2 1 1 3 3 3 1 Major Facilitator Superfamily MFS_2 PF13347.1 EXF77427.1 - 3.1e-13 48.9 15.2 5.1e-07 28.4 1.6 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein DUF3176 PF11374.3 EXF77429.1 - 2.3e-39 133.7 1.4 5.5e-39 132.4 1.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Tyrosinase PF00264.15 EXF77430.1 - 2e-35 122.9 3.2 2e-35 122.9 2.2 1.4 2 0 0 2 2 2 1 Common central domain of tyrosinase AIRS PF00586.19 EXF77430.1 - 0.038 14.2 0.0 0.086 13.0 0.0 1.7 1 1 0 1 1 1 0 AIR synthase related protein, N-terminal domain Dehydratase_hem PF13816.1 EXF77431.1 - 8.5e-102 340.3 0.0 9.7e-102 340.1 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.1 EXF77431.1 - 5.4e-06 26.4 0.0 0.041 13.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) Lactamase_B PF00753.22 EXF77433.1 - 6e-10 39.0 1.2 1.2e-09 38.0 0.8 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EXF77433.1 - 1.3e-05 24.8 0.9 3.6e-05 23.3 0.6 1.7 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Methyltransf_23 PF13489.1 EXF77434.1 - 2.1e-15 56.8 0.0 5.8e-15 55.3 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EXF77434.1 - 9.1e-14 51.1 0.0 1.3e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 EXF77434.1 - 3.7e-12 46.1 0.0 5.2e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF77434.1 - 6e-11 42.6 0.0 4.5e-10 39.7 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF77434.1 - 2e-10 41.0 0.0 7.1e-10 39.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF77434.1 - 4.1e-10 40.2 0.0 1.8e-09 38.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF77434.1 - 9e-08 32.5 0.1 4.9e-07 30.1 0.0 2.2 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF77434.1 - 2.1e-07 30.9 0.0 4.4e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EXF77434.1 - 0.00011 21.8 0.0 0.00019 21.0 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EXF77434.1 - 0.0017 17.5 0.0 0.045 12.8 0.0 2.1 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.7 EXF77434.1 - 0.023 14.2 0.0 0.06 12.8 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF938) RrnaAD PF00398.15 EXF77434.1 - 0.024 13.6 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Pex24p PF06398.6 EXF77436.1 - 4.6e-103 344.7 0.3 5.7e-103 344.4 0.2 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin Herpes_LP PF03363.8 EXF77436.1 - 0.0042 16.6 2.7 0.01 15.4 1.9 1.6 1 0 0 1 1 1 1 Herpesvirus leader protein DUF3176 PF11374.3 EXF77439.1 - 2.2e-36 124.0 0.1 4e-36 123.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF2919 PF11143.3 EXF77439.1 - 0.12 12.1 2.9 0.13 12.0 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2919) FAA_hydrolase PF01557.13 EXF77440.1 - 4.3e-57 193.0 0.0 5.5e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAD_binding_3 PF01494.14 EXF77441.1 - 1.1e-26 93.7 0.1 1.4e-26 93.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF77441.1 - 1.6e-11 43.7 1.4 1.7e-07 30.4 0.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF77441.1 - 9.3e-08 31.9 1.8 2.2e-07 30.7 0.4 2.3 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EXF77441.1 - 1.7e-06 27.1 1.4 3e-06 26.3 1.0 1.3 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EXF77441.1 - 6.2e-06 25.0 0.7 0.00011 21.0 0.2 2.5 2 1 1 3 3 3 1 Tryptophan halogenase HI0933_like PF03486.9 EXF77441.1 - 2e-05 23.2 0.4 0.011 14.1 0.5 2.2 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.7 EXF77441.1 - 5.7e-05 22.1 1.5 0.00021 20.3 0.3 2.2 2 1 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 EXF77441.1 - 6e-05 23.3 0.0 0.00086 19.6 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF77441.1 - 0.00014 21.0 0.1 0.00029 19.9 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EXF77441.1 - 0.00043 20.2 0.4 0.00099 19.0 0.3 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EXF77441.1 - 0.002 17.2 2.1 0.002 17.2 1.5 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EXF77441.1 - 0.0031 17.2 0.0 0.0056 16.4 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding GIDA PF01134.17 EXF77441.1 - 0.0035 16.2 0.8 0.0051 15.7 0.5 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A SE PF08491.5 EXF77441.1 - 0.0044 15.8 0.0 0.015 14.1 0.0 1.8 1 1 0 1 1 1 1 Squalene epoxidase Rossmann-like PF10727.4 EXF77441.1 - 0.0063 16.2 0.3 0.017 14.8 0.0 1.8 2 0 0 2 2 2 1 Rossmann-like domain Pyr_redox_3 PF13738.1 EXF77441.1 - 0.0072 16.4 0.8 0.012 15.7 0.2 1.8 2 1 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EXF77441.1 - 0.034 13.8 0.2 0.058 13.0 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EXF77441.1 - 0.046 13.1 0.4 0.082 12.3 0.3 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EXF77441.1 - 0.071 12.4 0.2 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Potex_coat PF06184.6 EXF77441.1 - 0.072 12.4 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Potexvirus coat protein Amino_oxidase PF01593.19 EXF77441.1 - 0.11 11.6 1.4 1.2 8.1 0.9 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Zn_clus PF00172.13 EXF77443.1 - 9e-10 38.3 5.6 1.6e-09 37.4 3.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phage_lambda_P PF06992.6 EXF77443.1 - 0.15 11.3 0.0 0.31 10.2 0.0 1.4 1 1 0 1 1 1 0 Replication protein P Cupin_2 PF07883.6 EXF77444.1 - 2.3e-24 84.6 0.1 1.3e-16 59.8 0.1 2.4 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EXF77444.1 - 2.4e-05 24.0 0.1 0.0038 16.9 0.1 2.3 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EXF77444.1 - 0.00033 20.0 0.0 0.12 11.7 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.7 EXF77444.1 - 0.0028 17.0 0.0 0.15 11.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF861) CENP-C_C PF11699.3 EXF77444.1 - 0.018 14.9 0.0 0.086 12.8 0.0 1.9 2 0 0 2 2 2 0 Mif2/CENP-C like ARD PF03079.9 EXF77444.1 - 0.076 12.9 0.0 0.22 11.4 0.0 1.7 2 0 0 2 2 2 0 ARD/ARD' family MFS_1 PF07690.11 EXF77445.1 - 7.1e-27 94.0 18.4 7.1e-27 94.0 12.7 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF77445.1 - 2e-07 29.9 5.4 2e-07 29.9 3.8 2.7 3 0 0 3 3 3 1 Sugar (and other) transporter Arrestin_N PF00339.24 EXF77446.1 - 2.8e-05 23.9 0.0 9.4e-05 22.2 0.0 1.9 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 EXF77446.1 - 0.00041 19.6 0.0 0.00058 19.1 0.0 1.2 1 0 0 1 1 1 1 Bul1 C terminus Bul1_N PF04425.7 EXF77446.1 - 0.00052 18.7 0.7 0.049 12.1 0.1 2.9 1 1 2 3 3 3 1 Bul1 N terminus MFS_1 PF07690.11 EXF77447.1 - 6.8e-24 84.2 36.7 7.5e-24 84.0 24.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF77447.1 - 1.5e-12 46.8 6.4 1.5e-12 46.8 4.5 2.9 2 1 0 2 2 2 1 Sugar (and other) transporter UQ_con PF00179.21 EXF77448.1 - 3.6e-26 91.2 0.2 5e-26 90.8 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EXF77448.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Prokaryotic E2 family B Bac_surface_Ag PF01103.18 EXF77449.1 - 2.6e-35 122.4 0.4 3.3e-35 122.0 0.3 1.1 1 0 0 1 1 1 1 Surface antigen FAD_binding_4 PF01565.18 EXF77450.1 - 1.5e-20 73.1 6.3 2.3e-20 72.4 4.3 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF77450.1 - 1.1e-07 31.6 0.0 2.2e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like RRM_1 PF00076.17 EXF77452.1 - 1.1e-29 101.8 0.0 1.8e-13 49.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF77452.1 - 1.2e-24 86.0 0.0 2e-12 46.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HLH PF00010.21 EXF77452.1 - 8.3e-13 47.8 1.1 2.9e-12 46.0 0.7 2.0 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain RRM_5 PF13893.1 EXF77452.1 - 2.3e-12 46.5 0.0 2.3e-08 33.7 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HALZ PF02183.13 EXF77452.1 - 0.027 14.1 0.6 0.052 13.2 0.4 1.4 1 0 0 1 1 1 0 Homeobox associated leucine zipper RRM_3 PF08777.6 EXF77452.1 - 0.065 13.0 0.1 0.52 10.1 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif DivIC PF04977.10 EXF77452.1 - 0.28 10.7 0.9 1.2 8.6 0.6 2.0 1 0 0 1 1 1 0 Septum formation initiator SymE_toxin PF08845.5 EXF77453.1 - 0.14 11.9 0.2 0.26 11.1 0.2 1.3 1 0 0 1 1 1 0 Toxin SymE, type I toxin-antitoxin system Zn_clus PF00172.13 EXF77455.1 - 1.8e-07 30.9 13.3 3e-07 30.2 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDK2AP PF09806.4 EXF77455.1 - 0.083 13.1 11.6 0.25 11.5 0.4 3.2 3 0 0 3 3 3 0 Cyclin-dependent kinase 2-associated protein TPR_11 PF13414.1 EXF77456.1 - 3e-24 84.4 11.2 1.9e-10 40.2 0.5 4.5 2 2 2 4 4 4 4 TPR repeat TPR_2 PF07719.12 EXF77456.1 - 6.6e-24 81.8 5.5 1e-06 28.1 0.0 6.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 EXF77456.1 - 1.5e-23 81.3 5.4 7.6e-08 31.6 0.0 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EXF77456.1 - 6.1e-19 66.8 9.1 8.3e-06 26.0 0.0 6.1 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EXF77456.1 - 5.4e-16 58.7 11.0 6.5e-06 26.6 0.1 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EXF77456.1 - 2.2e-15 55.5 5.7 0.0022 18.0 0.0 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.1 EXF77456.1 - 3.6e-14 52.4 3.6 3.1e-07 30.2 0.5 4.4 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EXF77456.1 - 9.9e-14 51.4 8.8 0.00014 22.0 3.8 4.9 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 EXF77456.1 - 2.4e-13 48.7 4.1 0.0056 16.3 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EXF77456.1 - 4.2e-12 44.9 0.2 0.00012 21.6 0.0 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EXF77456.1 - 3.4e-09 36.5 4.9 0.081 13.4 0.1 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EXF77456.1 - 8.9e-08 31.8 3.3 0.02 14.7 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.1 EXF77456.1 - 1.4e-06 28.2 12.1 0.0019 18.2 0.2 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat DUF484 PF04340.7 EXF77456.1 - 0.0038 16.7 0.0 0.0092 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF484 TPR_10 PF13374.1 EXF77456.1 - 0.011 15.6 2.2 0.6 10.1 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.1 EXF77456.1 - 0.028 13.4 8.3 0.47 9.4 0.5 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat NatB_MDM20 PF09797.4 EXF77456.1 - 0.028 13.1 0.0 0.06 12.0 0.0 1.5 1 0 0 1 1 1 0 N-acetyltransferase B complex (NatB) non catalytic subunit Tim17 PF02466.14 EXF77456.1 - 0.05 13.6 4.4 0.97 9.4 0.9 2.6 2 0 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family RNase_T PF00929.19 EXF77457.1 - 1.1e-20 74.5 0.0 1.6e-20 73.9 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DUF4592 PF15262.1 EXF77457.1 - 0.49 10.9 3.8 0.97 9.9 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4592) TMF_TATA_bd PF12325.3 EXF77458.1 - 0.012 15.2 18.3 0.65 9.7 6.7 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF972 PF06156.8 EXF77458.1 - 0.013 15.8 20.5 0.2 12.0 1.4 4.4 1 1 3 5 5 5 0 Protein of unknown function (DUF972) FAM72 PF14976.1 EXF77458.1 - 0.014 15.2 0.3 0.027 14.3 0.2 1.4 1 0 0 1 1 1 0 FAM72 protein ERM PF00769.14 EXF77458.1 - 0.023 14.2 16.1 0.14 11.6 3.6 2.4 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Yippee-Mis18 PF03226.9 EXF77458.1 - 0.029 14.3 0.1 0.094 12.7 0.1 1.8 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Phage_glycop_gL PF11108.3 EXF77458.1 - 0.049 13.5 0.5 5.7 6.9 0.0 2.7 2 0 0 2 2 2 0 Viral glycoprotein L DASH_Dad4 PF08650.5 EXF77458.1 - 0.099 12.5 1.5 2.9 7.8 0.4 2.8 2 0 0 2 2 2 0 DASH complex subunit Dad4 Spectrin PF00435.16 EXF77458.1 - 0.13 12.5 12.0 0.66 10.2 0.0 3.2 3 0 0 3 3 3 0 Spectrin repeat ORF6C PF10552.4 EXF77458.1 - 0.19 11.4 6.8 5.1 6.8 0.6 3.4 3 0 0 3 3 3 0 ORF6C domain GvpK PF05121.7 EXF77458.1 - 0.23 11.2 0.1 0.23 11.2 0.1 3.2 3 0 0 3 3 3 0 Gas vesicle protein K Tropomyosin_1 PF12718.2 EXF77458.1 - 0.32 10.8 17.8 2.4 7.9 4.7 2.9 1 1 2 3 3 3 0 Tropomyosin like DUF643 PF04867.7 EXF77458.1 - 0.4 11.0 3.2 0.57 10.5 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF643) TPR_MLP1_2 PF07926.7 EXF77458.1 - 0.54 9.9 20.9 0.044 13.5 5.8 3.1 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.6 EXF77458.1 - 0.88 9.5 12.7 2.6 8.0 0.9 4.9 5 2 1 6 6 5 0 Flagella accessory protein C (FlaC) SNARE PF05739.14 EXF77458.1 - 1.4 8.6 7.6 0.14 11.8 0.3 3.2 3 1 0 3 3 3 0 SNARE domain Filament PF00038.16 EXF77458.1 - 2.3 7.6 19.9 0.1 12.0 5.2 2.7 1 1 1 2 2 2 0 Intermediate filament protein DUF1664 PF07889.7 EXF77458.1 - 3.2 7.5 14.3 0.56 10.0 0.8 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) IncA PF04156.9 EXF77458.1 - 4.5 6.8 26.9 0.61 9.6 7.0 2.9 1 1 2 3 3 3 0 IncA protein Atg14 PF10186.4 EXF77458.1 - 4.5 6.1 21.4 7.5 5.3 5.9 2.9 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 FliJ PF02050.11 EXF77458.1 - 5.6 7.0 16.0 1.6 8.8 2.0 3.6 1 1 3 4 4 4 0 Flagellar FliJ protein Fib_alpha PF08702.5 EXF77458.1 - 6.2 6.9 21.5 0.37 10.9 4.4 2.9 2 1 2 4 4 3 0 Fibrinogen alpha/beta chain family DUF2730 PF10805.3 EXF77458.1 - 9.7 5.9 9.7 8.4 6.1 0.1 4.1 2 2 3 5 5 5 0 Protein of unknown function (DUF2730) zf-MYND PF01753.13 EXF77459.1 - 1.7e-09 37.3 11.9 3.5e-09 36.3 8.3 1.6 1 0 0 1 1 1 1 MYND finger SET PF00856.23 EXF77459.1 - 1.1e-06 29.0 0.0 2.3e-06 28.0 0.0 1.8 1 1 0 1 1 1 1 SET domain MRL1 PF13003.2 EXF77459.1 - 0.0023 17.7 0.0 0.0049 16.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L1 SUI1 PF01253.17 EXF77460.1 - 3.5e-29 100.4 4.7 3.5e-29 100.4 3.3 1.4 2 0 0 2 2 2 1 Translation initiation factor SUI1 Ribosomal_S19 PF00203.16 EXF77464.1 - 1.2e-32 111.3 0.2 1.8e-32 110.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 Oxidored_FMN PF00724.15 EXF77465.1 - 9.4e-85 284.5 0.0 1.3e-84 284.1 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Tim17 PF02466.14 EXF77466.1 - 8.5e-29 100.1 0.4 1.3e-28 99.5 0.3 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family PRP8_domainIV PF12134.3 EXF77466.1 - 0.1 11.9 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 PRP8 domain IV core MoaF PF10703.4 EXF77468.1 - 0.054 12.5 0.0 0.096 11.7 0.0 1.3 1 0 0 1 1 1 0 Molybdenum cofactor biosynthesis protein F BNR_2 PF13088.1 EXF77469.1 - 1.2e-18 67.3 1.4 5.3e-11 42.3 0.1 2.5 2 1 0 2 2 2 2 BNR repeat-like domain BNR PF02012.15 EXF77469.1 - 5.9e-09 34.4 18.6 0.016 14.9 0.3 5.8 5 0 0 5 5 5 4 BNR/Asp-box repeat Mo-co_dimer PF03404.11 EXF77469.1 - 0.93 9.1 6.5 1.6 8.3 0.0 3.1 4 0 0 4 4 4 0 Mo-co oxidoreductase dimerisation domain Rrn6 PF10214.4 EXF77470.1 - 0.84 7.6 2.7 1 7.3 1.9 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Brix PF04427.13 EXF77471.1 - 6.7e-35 120.4 0.0 9.1e-35 120.0 0.0 1.2 1 0 0 1 1 1 1 Brix domain DUF4431 PF14485.1 EXF77471.1 - 0.13 11.9 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4431) ADH_zinc_N PF00107.21 EXF77472.1 - 5.5e-13 48.5 0.2 1e-12 47.7 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF77472.1 - 0.0006 19.5 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Aldo_ket_red PF00248.16 EXF77474.1 - 1.2e-57 194.8 0.0 1.5e-57 194.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family HHH_7 PF14635.1 EXF77474.1 - 0.073 13.2 0.1 0.29 11.2 0.0 1.9 1 1 1 2 2 2 0 Helix-hairpin-helix motif zf-met PF12874.2 EXF77476.1 - 0.017 15.3 5.2 0.74 10.0 0.4 3.2 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EXF77476.1 - 0.026 14.8 19.1 0.22 11.9 1.7 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF77476.1 - 0.062 13.6 1.1 0.062 13.6 0.8 3.2 3 0 0 3 3 3 0 Zinc finger, C2H2 type Imm42 PF15601.1 EXF77477.1 - 0.027 13.8 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 42 LSM PF01423.17 EXF77478.1 - 4.6e-20 70.9 0.1 5.3e-20 70.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EXF77478.1 - 0.00013 21.8 0.1 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 EXF77478.1 - 0.037 13.8 0.1 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 Scd6-like Sm domain SpoA PF01052.15 EXF77478.1 - 0.13 11.8 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Surface presentation of antigens (SPOA) Rad60-SLD PF11976.3 EXF77479.1 - 1.1e-21 76.2 0.1 4.3e-20 71.1 0.1 2.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EXF77479.1 - 9.1e-06 24.9 0.0 4.3e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Ubiquitin family Ank_2 PF12796.2 EXF77480.1 - 1.9e-50 169.1 7.5 3.4e-15 56.1 0.0 9.4 4 3 3 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EXF77480.1 - 4.1e-38 127.3 13.9 4.9e-06 26.0 0.0 13.0 13 0 0 13 13 13 8 Ankyrin repeat Ank_3 PF13606.1 EXF77480.1 - 1.4e-33 111.5 4.5 0.0012 18.8 0.0 12.8 14 0 0 14 14 14 8 Ankyrin repeat Ank_4 PF13637.1 EXF77480.1 - 1.4e-31 108.2 9.0 2.8e-06 27.6 0.0 11.4 10 3 3 13 13 13 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF77480.1 - 2.3e-31 107.0 15.5 0.0028 17.8 0.4 10.9 11 0 0 11 11 11 8 Ankyrin repeats (many copies) DUF1843 PF08898.5 EXF77480.1 - 0.051 13.6 0.1 2 8.4 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) Orbi_VP5 PF00901.12 EXF77480.1 - 0.094 10.9 0.2 0.42 8.7 0.0 1.9 2 0 0 2 2 2 0 Orbivirus outer capsid protein VP5 CENP-B_dimeris PF09026.5 EXF77481.1 - 0.65 10.2 5.2 1.1 9.4 3.6 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain bZIP_2 PF07716.10 EXF77482.1 - 0.00091 19.0 14.1 0.0015 18.3 9.8 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EXF77482.1 - 0.11 12.4 14.0 1.3 9.0 9.7 2.1 1 1 0 1 1 1 0 bZIP transcription factor DivIC PF04977.10 EXF77482.1 - 0.3 10.6 5.9 0.13 11.7 2.5 1.5 1 1 0 1 1 1 0 Septum formation initiator DUF737 PF05300.6 EXF77482.1 - 1.4 8.8 9.9 4.3 7.2 6.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF737) CDC37_N PF03234.9 EXF77484.1 - 1.2e-58 198.2 1.8 1.2e-58 198.2 1.2 2.6 4 0 0 4 4 4 1 Cdc37 N terminal kinase binding CDC37_M PF08565.6 EXF77484.1 - 4.7e-47 159.6 2.4 1.2e-46 158.3 1.7 1.6 1 0 0 1 1 1 1 Cdc37 Hsp90 binding domain CDC37_C PF08564.5 EXF77484.1 - 3e-25 87.9 0.3 3e-25 87.9 0.2 2.8 2 1 0 2 2 2 1 Cdc37 C terminal domain DUF1268 PF06896.6 EXF77484.1 - 0.02 15.2 1.0 0.02 15.2 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1268) MecA_N PF05223.6 EXF77484.1 - 1.9 8.5 6.4 2.3 8.3 0.7 3.4 2 1 1 3 3 3 0 NTF2-like N-terminal transpeptidase domain DUF3535 PF12054.3 EXF77485.1 - 8e-137 456.4 0.3 5.3e-136 453.7 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EXF77485.1 - 7.1e-73 244.9 0.0 1e-72 244.5 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain HEAT PF02985.17 EXF77485.1 - 3.9e-15 54.4 1.7 0.015 15.3 0.0 8.3 7 0 0 7 7 7 4 HEAT repeat Helicase_C PF00271.26 EXF77485.1 - 1.8e-14 53.3 0.0 4.3e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.2 EXF77485.1 - 1.3e-06 28.7 0.4 0.14 12.5 0.0 4.0 2 1 1 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 EXF77485.1 - 1.2e-05 25.4 14.3 0.0055 16.9 0.0 7.4 7 2 0 7 7 7 1 HEAT repeats HEAT_EZ PF13513.1 EXF77485.1 - 0.00023 21.5 7.0 15 6.2 0.0 8.2 8 0 0 8 8 8 1 HEAT-like repeat Adaptin_N PF01602.15 EXF77485.1 - 0.72 8.1 2.3 14 3.8 0.1 3.1 3 0 0 3 3 3 0 Adaptin N terminal region SMC_N PF02463.14 EXF77486.1 - 7.9e-59 198.5 22.4 1.4e-58 197.7 15.5 1.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EXF77486.1 - 8.9e-28 96.6 0.0 4.7e-27 94.3 0.0 2.4 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EXF77486.1 - 1.3e-16 61.4 0.4 1.1e-07 32.0 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EXF77486.1 - 2.3e-05 24.8 55.1 2.3e-05 24.8 38.2 7.5 2 2 2 4 4 4 1 AAA domain AAA_29 PF13555.1 EXF77486.1 - 0.0006 19.2 0.0 0.0016 17.8 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain Laminin_II PF06009.7 EXF77486.1 - 0.0066 16.1 1.6 0.0066 16.1 1.1 8.4 4 2 5 10 10 10 1 Laminin Domain II ABC_tran PF00005.22 EXF77486.1 - 0.45 10.8 0.0 0.45 10.8 0.0 6.7 3 2 1 5 5 5 0 ABC transporter Reo_sigmaC PF04582.7 EXF77486.1 - 7 5.7 24.3 0.38 9.8 1.2 4.7 4 1 1 5 5 5 0 Reovirus sigma C capsid protein E1-E2_ATPase PF00122.15 EXF77487.1 - 4.1e-64 215.7 0.5 4.1e-64 215.7 0.3 2.4 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EXF77487.1 - 1.7e-21 77.6 0.1 3.8e-21 76.4 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EXF77487.1 - 3.2e-11 43.7 0.0 7e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EXF77487.1 - 1.9e-10 40.0 0.0 6.1e-10 38.4 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EXF77487.1 - 0.0019 17.8 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EXF77487.1 - 0.041 13.8 0.0 0.09 12.7 0.0 1.5 1 0 0 1 1 1 0 Putative hydrolase of sodium-potassium ATPase alpha subunit STE PF02200.11 EXF77490.1 - 4.5e-62 207.0 0.4 8.7e-62 206.1 0.1 1.6 2 0 0 2 2 2 1 STE like transcription factor zf-C2H2 PF00096.21 EXF77490.1 - 0.00026 21.1 3.8 0.00076 19.6 2.7 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF77490.1 - 0.0022 18.2 2.3 0.0022 18.2 1.6 2.0 2 0 0 2 2 2 1 C2H2-type zinc finger Daxx PF03344.10 EXF77491.1 - 2.1 6.7 36.5 3.7 5.9 25.2 1.4 1 1 0 1 1 1 0 Daxx Family DUF1900 PF08954.6 EXF77492.1 - 2.7e-49 166.1 0.0 3.2e-48 162.6 0.0 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EXF77492.1 - 2.8e-33 113.3 0.0 6.7e-33 112.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EXF77492.1 - 1e-27 94.9 1.8 8.9e-08 31.7 0.3 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.3 EXF77492.1 - 0.0043 15.2 0.4 0.96 7.5 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Phage_HK97_TLTM PF06120.6 EXF77492.1 - 0.009 15.3 0.8 0.015 14.7 0.5 1.2 1 0 0 1 1 1 1 Tail length tape measure protein Gp58 PF07902.6 EXF77492.1 - 0.034 12.3 0.9 0.046 11.9 0.6 1.1 1 0 0 1 1 1 0 gp58-like protein Nucleoporin_N PF08801.6 EXF77492.1 - 0.092 11.4 0.1 1.3 7.6 0.1 2.2 1 1 1 2 2 2 0 Nup133 N terminal like Spc7 PF08317.6 EXF77492.1 - 0.3 9.7 2.7 0.41 9.2 1.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.8 EXF77492.1 - 0.49 9.4 1.1 0.79 8.7 0.8 1.3 1 0 0 1 1 1 0 TMPIT-like protein Mif2_N PF15624.1 EXF77492.1 - 0.74 10.4 8.4 1.4 9.4 5.8 1.5 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal SlyX PF04102.7 EXF77492.1 - 2.6 8.4 5.7 2.1 8.7 0.8 2.5 2 1 0 2 2 2 0 SlyX PAT1 PF09770.4 EXF77492.1 - 6.9 4.7 19.9 9.3 4.3 13.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4404 PF14357.1 EXF77492.1 - 9.1 6.7 7.7 1.1 9.7 2.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Anillin PF08174.6 EXF77493.1 - 6e-37 126.8 0.4 1.7e-36 125.3 0.3 1.9 1 0 0 1 1 1 1 Cell division protein anillin PH PF00169.24 EXF77493.1 - 2.5e-08 34.0 0.0 7.9e-08 32.4 0.0 1.9 1 0 0 1 1 1 1 PH domain His_biosynth PF00977.16 EXF77494.1 - 5e-34 117.5 0.0 6.1e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 Histidine biosynthesis protein Ribul_P_3_epim PF00834.14 EXF77494.1 - 0.045 12.8 0.0 0.072 12.1 0.0 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family DUF3176 PF11374.3 EXF77495.1 - 8.5e-32 109.3 0.7 5.2e-31 106.7 0.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Dus PF01207.12 EXF77496.1 - 5.4e-55 186.4 0.0 9.2e-55 185.6 0.0 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Carb_anhydrase PF00194.16 EXF77498.1 - 3e-25 88.6 0.0 4.4e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase DUF4655 PF15548.1 EXF77499.1 - 0.14 11.0 3.6 0.17 10.7 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4655) AAA PF00004.24 EXF77500.1 - 3e-46 156.9 0.0 3.2e-42 143.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EXF77500.1 - 1.4e-08 34.9 0.1 0.0002 21.4 0.1 3.4 3 1 0 3 3 2 2 AAA ATPase domain IstB_IS21 PF01695.12 EXF77500.1 - 4e-06 26.3 0.0 9.1e-05 21.9 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 EXF77500.1 - 6.9e-06 26.0 0.0 2e-05 24.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EXF77500.1 - 7.7e-06 26.0 0.3 0.0017 18.5 0.0 4.0 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.9 EXF77500.1 - 0.001 18.8 0.0 0.005 16.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EXF77500.1 - 0.0012 19.6 0.0 0.02 15.7 0.0 3.1 3 0 0 3 3 2 1 AAA domain TIP49 PF06068.8 EXF77500.1 - 0.0082 14.8 0.0 0.015 14.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EXF77500.1 - 0.0086 15.8 0.2 0.031 14.0 0.1 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EXF77500.1 - 0.0088 15.9 0.0 0.033 14.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EXF77500.1 - 0.0088 15.9 0.0 0.0088 15.9 0.0 3.4 4 0 0 4 4 4 1 AAA domain AAA_18 PF13238.1 EXF77500.1 - 0.0097 16.2 0.0 0.059 13.6 0.0 2.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EXF77500.1 - 0.0098 14.9 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus RNA_helicase PF00910.17 EXF77500.1 - 0.0099 16.0 0.0 0.064 13.4 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_28 PF13521.1 EXF77500.1 - 0.026 14.4 0.0 0.071 13.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EXF77500.1 - 0.031 14.3 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 EXF77500.1 - 0.045 13.1 0.0 0.15 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EXF77500.1 - 0.058 12.5 0.1 0.14 11.3 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Torsin PF06309.6 EXF77500.1 - 0.058 13.2 0.1 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 Torsin Parvo_NS1 PF01057.12 EXF77500.1 - 0.096 11.5 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 EXF77500.1 - 0.1 12.2 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EXF77500.1 - 0.12 11.9 0.1 0.46 10.1 0.1 2.1 1 1 0 1 1 1 0 NACHT domain Sigma54_activat PF00158.21 EXF77500.1 - 0.19 11.2 0.0 3.7 6.9 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain adh_short PF00106.20 EXF77501.1 - 4.5e-24 85.2 0.0 7.2e-24 84.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF77501.1 - 1.8e-08 34.2 0.0 3.6e-08 33.2 0.0 1.4 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF77501.1 - 5.6e-06 26.2 0.0 7.2e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EXF77501.1 - 7.8e-05 22.7 0.1 0.00014 21.9 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF77501.1 - 0.0034 16.8 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EXF77501.1 - 0.0093 15.1 0.0 0.32 10.0 0.0 2.2 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.14 EXF77501.1 - 0.029 13.4 0.1 0.058 12.4 0.1 1.4 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EXF77501.1 - 0.082 12.7 0.6 0.19 11.5 0.4 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Saccharop_dh PF03435.13 EXF77501.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase DSBA PF01323.15 EXF77502.1 - 9.4e-14 51.4 0.0 6.5e-06 25.8 0.0 2.1 2 0 0 2 2 2 2 DSBA-like thioredoxin domain BCNT PF07572.7 EXF77503.1 - 5.1e-25 87.2 2.8 1.1e-24 86.1 1.9 1.5 1 0 0 1 1 1 1 Bucentaur or craniofacial development WD40 PF00400.27 EXF77505.1 - 7.3e-20 70.0 16.7 1.8e-05 24.4 0.3 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat MraZ PF02381.13 EXF77505.1 - 0.065 12.9 0.0 13 5.6 0.0 2.7 2 0 0 2 2 2 0 MraZ protein BBS2_N PF14781.1 EXF77505.1 - 0.14 11.7 0.0 0.38 10.3 0.0 1.7 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal Cwf_Cwc_15 PF04889.7 EXF77505.1 - 7.3 6.2 8.7 1.2 8.7 3.3 1.6 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SNF2_N PF00176.18 EXF77506.1 - 7.8e-83 277.7 1.3 7.8e-83 277.7 0.9 2.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EXF77506.1 - 6.1e-20 70.9 0.1 1.8e-19 69.4 0.1 1.8 1 0 0 1 1 1 1 Bromodomain Helicase_C PF00271.26 EXF77506.1 - 1e-17 63.7 0.2 6.8e-17 61.0 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SnAC PF14619.1 EXF77506.1 - 6.2e-17 61.5 1.3 6.2e-17 61.5 0.9 3.8 3 0 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex HSA PF07529.8 EXF77506.1 - 2.3e-12 46.4 12.1 2.3e-12 46.4 8.4 3.7 4 0 0 4 4 4 1 HSA QLQ PF08880.6 EXF77506.1 - 1.2e-10 40.6 5.4 5.1e-10 38.5 3.7 2.2 1 0 0 1 1 1 1 QLQ HET PF06985.6 EXF77507.1 - 5.3e-22 78.4 0.0 3.1e-21 76.0 0.0 2.2 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CAF-1_p150 PF11600.3 EXF77507.1 - 0.096 12.0 1.2 0.16 11.3 0.8 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1777 PF08648.7 EXF77507.1 - 3.5 7.3 50.1 0.53 9.9 15.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1777) MIF4G PF02854.14 EXF77510.1 - 1e-23 83.8 0.0 2.1e-23 82.8 0.0 1.6 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EXF77510.1 - 1.2e-21 76.5 0.0 3.6e-21 74.9 0.0 1.9 2 0 0 2 2 2 1 MA3 domain FAM176 PF14851.1 EXF77510.1 - 0.064 12.9 3.5 0.2 11.3 2.5 1.8 1 0 0 1 1 1 0 FAM176 family TFIIA PF03153.8 EXF77510.1 - 0.97 9.2 14.3 0.12 12.2 6.5 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DPM2 PF07297.7 EXF77511.1 - 1e-29 102.6 1.1 1.2e-29 102.3 0.7 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EXF77511.1 - 0.0003 20.4 0.7 0.00031 20.3 0.5 1.1 1 0 0 1 1 1 1 PIG-P DUF4229 PF14012.1 EXF77511.1 - 0.0011 18.8 0.6 0.0011 18.8 0.4 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) DUF4083 PF13314.1 EXF77511.1 - 0.0077 16.0 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4083) DUF1049 PF06305.6 EXF77511.1 - 0.027 13.9 0.4 0.05 13.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Vg_Tdu PF07545.9 EXF77511.1 - 0.051 13.0 0.2 0.09 12.2 0.1 1.4 1 0 0 1 1 1 0 Vestigial/Tondu family COX14 PF14880.1 EXF77511.1 - 0.052 13.1 0.6 0.87 9.2 0.0 2.0 2 0 0 2 2 2 0 Cytochrome oxidase c assembly DUF4113 PF13438.1 EXF77513.1 - 0.058 12.9 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4113) SnoaL_4 PF13577.1 EXF77514.1 - 0.0013 18.5 1.9 0.004 17.0 1.3 1.7 1 1 0 1 1 1 1 SnoaL-like domain SnoaL_2 PF12680.2 EXF77514.1 - 0.03 14.7 0.2 0.049 14.0 0.1 1.5 1 1 0 1 1 1 0 SnoaL-like domain DUF4440 PF14534.1 EXF77514.1 - 0.14 12.3 1.6 0.22 11.7 1.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4440) Sugar_tr PF00083.19 EXF77515.1 - 2.9e-59 200.8 9.6 3.3e-59 200.6 6.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF77515.1 - 9e-05 21.3 49.3 0.00075 18.3 9.0 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3336 PF11815.3 EXF77516.1 - 4.1e-39 133.3 0.6 8.6e-39 132.3 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.17 EXF77516.1 - 1.5e-24 87.0 0.0 3.7e-24 85.7 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase Abhydrolase_5 PF12695.2 EXF77517.1 - 0.00015 21.5 0.0 0.0033 17.2 0.0 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family BBP1_N PF15271.1 EXF77517.1 - 0.03 14.7 0.0 0.042 14.2 0.0 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein PIG-S PF10510.4 EXF77518.1 - 4.8e-146 487.4 0.0 5.5e-146 487.2 0.0 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein AMP-binding PF00501.23 EXF77519.1 - 6.2e-76 255.4 0.0 1.2e-75 254.5 0.0 1.4 2 0 0 2 2 2 1 AMP-binding enzyme AMP-binding_C PF13193.1 EXF77519.1 - 5.6e-13 49.6 0.4 1.2e-12 48.5 0.1 1.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Abhydrolase_6 PF12697.2 EXF77520.1 - 7.6e-14 52.1 7.9 1.1e-13 51.6 5.5 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF77520.1 - 6.7e-05 22.6 0.1 0.00017 21.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family AhpC-TSA PF00578.16 EXF77521.1 - 5.3e-32 110.1 0.0 7e-32 109.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EXF77521.1 - 3.3e-12 46.1 0.0 4.4e-12 45.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EXF77521.1 - 7.1e-12 44.7 0.1 1.5e-11 43.7 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Kelch_3 PF13415.1 EXF77522.1 - 3.6e-21 74.7 4.6 5.5e-10 39.1 0.0 6.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_4 PF13418.1 EXF77522.1 - 4.1e-20 71.2 0.1 6.9e-09 35.3 0.0 5.2 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EXF77522.1 - 9.8e-13 47.6 3.8 0.00026 21.0 0.5 4.7 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.20 EXF77522.1 - 5e-11 41.9 0.1 0.0019 17.6 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.1 EXF77522.1 - 2.3e-10 40.1 5.3 0.00021 21.1 0.1 4.2 3 1 0 3 3 3 2 Kelch motif Kelch_2 PF07646.10 EXF77522.1 - 7.6e-08 31.8 0.2 0.00026 20.6 0.0 4.2 4 1 0 4 4 4 1 Kelch motif BTB PF00651.26 EXF77522.1 - 0.053 13.5 0.0 0.31 11.0 0.0 2.1 2 0 0 2 2 2 0 BTB/POZ domain DUF2236 PF09995.4 EXF77523.1 - 1.3e-06 27.9 0.1 1.9e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Myb_DNA-bind_6 PF13921.1 EXF77524.1 - 1.6e-05 24.9 0.1 3.7e-05 23.7 0.1 1.7 1 1 1 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EXF77524.1 - 0.0097 15.9 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Rap1_C PF11626.3 EXF77524.1 - 0.022 14.6 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain UbiA PF01040.13 EXF77525.1 - 2.5e-30 105.5 20.6 3.9e-30 104.9 14.3 1.4 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF3040 PF11239.3 EXF77525.1 - 0.032 14.2 0.2 0.12 12.3 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Med3 PF11593.3 EXF77525.1 - 7.1 5.7 10.1 9.3 5.3 7.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal AXE1 PF05448.7 EXF77526.1 - 0.065 11.7 0.3 0.12 10.8 0.0 1.5 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.2 EXF77527.1 - 4e-11 43.2 3.0 1e-10 41.8 2.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF77527.1 - 0.0045 16.5 0.0 0.0081 15.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EXF77527.1 - 0.024 14.2 0.0 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase Abhydrolase_8 PF06259.7 EXF77527.1 - 0.029 13.8 0.1 0.24 10.8 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase Cupin_2 PF07883.6 EXF77528.1 - 3.3e-08 32.9 0.0 5.1e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EXF77528.1 - 0.00076 18.9 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 EXF77528.1 - 0.0022 17.6 0.0 0.0025 17.4 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EXF77528.1 - 0.098 12.0 0.0 0.15 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) DUF3506 PF12014.3 EXF77529.1 - 4.1e-45 152.9 0.0 7.4e-45 152.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3506) F-box-like PF12937.2 EXF77529.1 - 8.4e-06 25.4 0.7 1.7e-05 24.4 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EXF77529.1 - 9.1e-05 22.0 0.1 0.00018 21.0 0.0 1.4 1 0 0 1 1 1 1 F-box domain Methyltransf_23 PF13489.1 EXF77530.1 - 1.4e-17 63.8 0.0 2.2e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EXF77530.1 - 1.7e-17 63.3 0.1 1.7e-15 56.8 0.1 2.2 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.7 EXF77530.1 - 1.9e-16 60.2 0.1 3.2e-15 56.3 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF77530.1 - 1.3e-14 54.0 0.0 1.6e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EXF77530.1 - 2.1e-13 50.5 0.0 1e-12 48.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF77530.1 - 3.9e-12 46.7 0.1 1.2e-11 45.1 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF77530.1 - 1.4e-08 34.9 0.1 1.3e-07 31.9 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF77530.1 - 2e-06 27.0 0.0 8.3e-05 21.8 0.0 2.2 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EXF77530.1 - 2.5e-06 27.5 0.0 7.4e-06 25.9 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF77530.1 - 0.00022 20.6 0.3 0.0079 15.5 0.2 2.2 2 0 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.14 EXF77530.1 - 0.00027 21.0 0.1 0.00046 20.2 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase MetW PF07021.7 EXF77530.1 - 0.00079 18.8 0.0 0.024 14.0 0.1 2.2 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW Methyltransf_24 PF13578.1 EXF77530.1 - 0.0089 16.8 0.1 0.03 15.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.8 EXF77530.1 - 0.012 14.9 0.1 0.021 14.1 0.1 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_32 PF13679.1 EXF77530.1 - 0.013 15.1 0.1 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EXF77530.1 - 0.017 14.3 0.0 0.034 13.3 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_PK PF05891.7 EXF77530.1 - 0.021 14.1 0.0 1 8.6 0.0 2.2 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase PCMT PF01135.14 EXF77530.1 - 0.042 13.3 0.1 0.3 10.5 0.1 1.9 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Peptidase_M50B PF13398.1 EXF77531.1 - 1.6e-56 190.8 18.2 2.1e-56 190.5 12.6 1.1 1 0 0 1 1 1 1 Peptidase M50B-like Peptidase_M50 PF02163.17 EXF77531.1 - 0.042 12.7 0.2 0.042 12.7 0.1 2.5 1 1 1 2 2 2 0 Peptidase family M50 ACR_tran PF00873.14 EXF77531.1 - 0.047 11.1 0.4 0.076 10.4 0.3 1.4 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Peptidase_M41 PF01434.13 EXF77531.1 - 0.13 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M41 DUF4360 PF14273.1 EXF77532.1 - 2.7e-09 36.9 0.2 3.2e-09 36.6 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4360) MFS_1 PF07690.11 EXF77533.1 - 9.1e-36 123.2 27.9 1.6e-35 122.4 19.1 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3671 PF12420.3 EXF77533.1 - 1.2 9.1 3.1 2.5 8.1 0.0 3.0 3 1 0 3 3 3 0 Protein of unknown function MutS_V PF00488.16 EXF77534.1 - 4.5e-79 265.1 0.5 7e-79 264.5 0.1 1.5 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 EXF77534.1 - 4.8e-51 173.4 0.1 8.5e-51 172.6 0.1 1.4 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EXF77534.1 - 1.5e-33 115.1 0.0 3.7e-33 113.9 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EXF77534.1 - 9.3e-15 54.9 0.0 2.9e-14 53.3 0.0 1.9 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EXF77534.1 - 2.4e-13 50.0 0.6 7.7e-13 48.4 0.4 2.0 1 0 0 1 1 1 1 MutS family domain IV AAA_23 PF13476.1 EXF77534.1 - 0.00014 22.2 1.4 0.0018 18.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EXF77534.1 - 0.036 13.6 0.0 0.09 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.1 EXF77534.1 - 0.07 13.0 1.3 0.14 12.1 0.1 2.1 2 0 0 2 2 2 0 AAA domain MFS_1 PF07690.11 EXF77535.1 - 4.2e-39 134.2 19.1 4.2e-39 134.2 13.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EXF77535.1 - 2.4e-06 26.0 4.3 3.5e-06 25.5 3.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) TMEM154 PF15102.1 EXF77536.1 - 0.00041 20.0 2.5 0.001 18.8 1.7 1.6 1 1 0 1 1 1 1 TMEM154 protein family Rax2 PF12768.2 EXF77536.1 - 0.0035 16.5 0.1 0.0045 16.2 0.0 1.1 1 0 0 1 1 1 1 Cortical protein marker for cell polarity OAD_gamma PF04277.8 EXF77536.1 - 0.027 14.8 0.0 0.22 11.9 0.0 2.0 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF3357 PF11837.3 EXF77536.1 - 0.051 13.4 0.2 0.15 11.9 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) gpUL132 PF11359.3 EXF77536.1 - 0.26 10.6 2.2 0.57 9.4 1.5 1.6 1 1 0 1 1 1 0 Glycoprotein UL132 Polysacc_synt_4 PF04669.8 EXF77537.1 - 4.9e-23 81.4 1.8 4.7e-22 78.2 1.2 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis Rota_NSP4 PF01452.11 EXF77537.1 - 0.048 12.9 0.5 0.36 10.1 0.6 2.0 2 0 0 2 2 2 0 Rotavirus non structural protein MFS_1 PF07690.11 EXF77539.1 - 2.4e-45 154.7 34.3 2.4e-45 154.7 23.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF77539.1 - 8.8e-10 37.7 7.5 8.8e-10 37.7 5.2 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter PK PF00224.16 EXF77540.1 - 7.8e-170 564.0 2.5 1e-169 563.6 1.7 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EXF77540.1 - 1.6e-30 105.0 0.0 4.8e-30 103.5 0.0 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EXF77540.1 - 3.6e-05 22.7 0.6 0.00022 20.1 0.2 2.2 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family IMPDH PF00478.20 EXF77540.1 - 0.0087 14.9 0.1 0.2 10.4 0.0 2.2 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain Het-C PF07217.6 EXF77542.1 - 1.1e-263 875.9 0.0 1.5e-263 875.5 0.0 1.1 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C GATA PF00320.22 EXF77543.1 - 1.2e-15 56.5 3.4 2e-15 55.8 2.3 1.4 1 0 0 1 1 1 1 GATA zinc finger Cast PF10174.4 EXF77543.1 - 0.088 10.8 0.1 0.12 10.4 0.1 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Ribosomal_S5_C PF03719.10 EXF77543.1 - 0.15 11.3 0.0 0.73 9.1 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain Glyco_hydro_12 PF01670.11 EXF77544.1 - 8.2e-13 48.4 2.3 1.5e-12 47.5 1.5 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 Mucin PF01456.12 EXF77544.1 - 0.034 13.9 12.7 0.06 13.1 8.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein NADH_u_ox_C PF12853.2 EXF77545.1 - 8.4e-33 111.9 0.1 1.3e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit NADH-u_ox-rdase PF10785.4 EXF77545.1 - 2.1e-25 88.7 0.1 3.5e-25 88.0 0.1 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit Swi3 PF07962.7 EXF77546.1 - 1.3e-29 101.6 0.1 2.6e-29 100.6 0.1 1.5 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 bZIP_2 PF07716.10 EXF77547.1 - 5.7e-07 29.2 14.3 1.8e-06 27.6 9.9 1.9 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EXF77547.1 - 0.00049 19.9 16.1 0.0011 18.9 11.1 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EXF77547.1 - 0.0061 16.8 10.9 0.015 15.5 7.6 1.6 1 0 0 1 1 1 1 bZIP Maf transcription factor DUF427 PF04248.7 EXF77548.1 - 6.9e-06 25.6 0.0 8.5e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Snf7 PF03357.16 EXF77549.1 - 3.6e-08 33.0 24.9 3.6e-08 33.0 17.3 1.5 1 1 1 2 2 2 1 Snf7 Ist1 PF03398.9 EXF77549.1 - 0.005 16.2 5.5 0.016 14.5 3.8 1.8 1 1 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway ASL_C PF08328.6 EXF77549.1 - 0.25 11.1 5.2 0.23 11.3 2.3 1.9 1 1 1 2 2 2 0 Adenylosuccinate lyase C-terminal Dynactin_p62 PF05502.8 EXF77549.1 - 0.93 8.1 11.5 1 8.0 8.0 1.1 1 0 0 1 1 1 0 Dynactin p62 family SATase_N PF06426.9 EXF77549.1 - 0.99 9.6 8.1 0.55 10.5 2.7 2.4 1 1 0 2 2 2 0 Serine acetyltransferase, N-terminal DUF1451 PF07295.6 EXF77549.1 - 3.8 7.2 9.7 0.58 9.9 3.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) DSHCT PF08148.7 EXF77550.1 - 5.3e-61 204.9 0.3 1.2e-60 203.8 0.2 1.6 1 0 0 1 1 1 1 DSHCT (NUC185) domain Transket_pyr PF02779.19 EXF77550.1 - 3.5e-45 153.6 0.0 7.1e-45 152.6 0.0 1.6 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EXF77550.1 - 2.8e-35 120.9 0.1 8.5e-35 119.3 0.1 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain DEAD PF00270.24 EXF77550.1 - 8.8e-21 74.1 0.0 2.3e-20 72.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF77550.1 - 5.5e-06 26.1 0.0 1.6e-05 24.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain rRNA_proc-arch PF13234.1 EXF77550.1 - 6.5e-05 22.2 1.5 0.00029 20.0 1.0 2.0 1 1 0 1 1 1 1 rRNA-processing arch domain ResIII PF04851.10 EXF77550.1 - 0.035 13.9 0.4 0.77 9.5 0.1 2.9 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Cut8_C PF08559.5 EXF77550.1 - 0.044 13.6 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Cut8 six-helix bundle Syntaxin PF00804.20 EXF77550.1 - 0.052 13.7 0.0 0.24 11.5 0.0 2.2 1 1 0 1 1 1 0 Syntaxin Sterol_MT_C PF08498.5 EXF77551.1 - 4.2e-27 93.8 0.2 6.7e-27 93.2 0.1 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EXF77551.1 - 7.8e-22 77.5 0.0 1.5e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF77551.1 - 3.2e-18 65.7 0.0 4.7e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF77551.1 - 2.8e-14 53.1 0.0 4.9e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF77551.1 - 1.5e-13 50.9 0.0 2.9e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EXF77551.1 - 1.4e-11 44.0 0.1 2e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EXF77551.1 - 4e-11 42.4 0.0 8e-11 41.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EXF77551.1 - 4.1e-11 43.4 0.0 9.3e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF77551.1 - 6e-11 42.6 0.0 1.4e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF77551.1 - 1.5e-09 37.8 0.0 4.2e-09 36.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EXF77551.1 - 3.1e-05 23.6 0.0 4.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EXF77551.1 - 6.9e-05 22.2 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EXF77551.1 - 0.00058 19.4 0.0 0.00095 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 EXF77551.1 - 0.0011 18.0 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MetW PF07021.7 EXF77551.1 - 0.0015 17.9 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.8 EXF77551.1 - 0.002 17.3 0.0 0.0036 16.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_29 PF03141.11 EXF77551.1 - 0.0035 15.7 0.0 0.0049 15.2 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_2 PF00891.13 EXF77551.1 - 0.015 14.4 0.2 0.032 13.4 0.0 1.6 2 0 0 2 2 2 0 O-methyltransferase Methyltransf_32 PF13679.1 EXF77551.1 - 0.019 14.6 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.1 EXF77551.1 - 0.027 15.3 0.0 0.081 13.7 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase domain TehB PF03848.9 EXF77551.1 - 0.041 13.0 0.0 0.071 12.2 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB RRM_1 PF00076.17 EXF77552.1 - 5.4e-09 35.5 0.0 9.2e-09 34.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF77552.1 - 4.4e-08 32.8 0.0 7.7e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF77552.1 - 8.6e-07 28.8 0.0 1.5e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EXF77552.1 - 0.015 15.1 0.0 0.033 14.0 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif Nup35_RRM_2 PF14605.1 EXF77552.1 - 0.037 13.8 0.0 0.064 13.0 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Complex1_LYR PF05347.10 EXF77553.1 - 3.7e-05 23.4 0.2 5.9e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EXF77553.1 - 4.9e-05 23.4 0.1 6.6e-05 23.0 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like DUF924 PF06041.6 EXF77553.1 - 0.015 15.0 0.2 0.016 14.9 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF924) DUF3186 PF11382.3 EXF77553.1 - 0.055 12.6 0.2 0.063 12.3 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) DnaJ PF00226.26 EXF77554.1 - 1.5e-19 69.4 1.1 1.5e-19 69.4 0.8 2.7 2 1 0 2 2 2 1 DnaJ domain TraH PF06122.6 EXF77554.1 - 0.08 11.7 4.1 0.15 10.8 2.9 1.4 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein SLT_2 PF13406.1 EXF77554.1 - 0.8 8.5 10.0 1.7 7.5 6.9 1.5 1 0 0 1 1 1 0 Transglycosylase SLT domain PAN_4 PF14295.1 EXF77555.1 - 0.013 15.2 0.8 0.027 14.1 0.6 1.5 1 0 0 1 1 1 0 PAN domain DUF1191 PF06697.7 EXF77555.1 - 0.016 14.0 0.1 0.021 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) CFEM PF05730.6 EXF77556.1 - 8.4e-10 38.3 15.5 1e-09 38.0 10.7 1.1 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.15 EXF77556.1 - 0.66 10.0 7.7 0.11 12.5 2.2 1.9 2 0 0 2 2 2 0 Gamma-thionin family DUF1691 PF07950.6 EXF77557.1 - 1.1e-40 137.9 6.3 6.7e-25 87.1 1.7 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1691) DUF2955 PF11168.3 EXF77557.1 - 0.076 12.6 1.7 1.5 8.5 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2955) zf-C2H2_jaz PF12171.3 EXF77558.1 - 4.9e-06 26.5 3.7 7.9e-06 25.8 2.6 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EXF77558.1 - 0.00052 20.1 0.9 0.00088 19.3 0.7 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.1 EXF77558.1 - 0.0072 16.5 0.1 0.013 15.7 0.1 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF77558.1 - 0.029 14.7 1.1 0.049 13.9 0.8 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EXF77558.1 - 0.036 14.1 0.3 0.052 13.6 0.2 1.2 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) DUF965 PF06135.7 EXF77558.1 - 0.051 13.6 0.0 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF965) Fungal_trans PF04082.13 EXF77559.1 - 1.6e-11 43.5 2.7 2.3e-11 43.0 1.0 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain F-box-like PF12937.2 EXF77560.1 - 5.3e-09 35.6 1.1 1.1e-08 34.7 0.7 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EXF77560.1 - 6.2e-07 28.9 2.1 1.2e-06 28.0 1.5 1.5 1 0 0 1 1 1 1 F-box domain ApbA_C PF08546.6 EXF77561.1 - 2.2e-26 92.2 0.1 4e-26 91.4 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EXF77561.1 - 1.2e-20 73.5 0.0 4.4e-20 71.6 0.0 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA DMAP_binding PF06464.6 EXF77561.1 - 0.091 13.3 1.0 1.1 9.8 0.0 2.4 2 0 0 2 2 2 0 DMAP1-binding Domain SNF2_N PF00176.18 EXF77562.1 - 4.1e-70 235.9 0.0 6.4e-70 235.3 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EXF77562.1 - 2.2e-13 49.8 0.0 6.3e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EXF77562.1 - 0.00023 20.7 0.0 0.00062 19.3 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ribosomal_S11 PF00411.14 EXF77563.1 - 9.8e-41 138.3 0.5 1.2e-40 138.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 DUF2252 PF10009.4 EXF77563.1 - 0.074 11.9 0.0 0.089 11.6 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) Ribosomal_L30_N PF08079.7 EXF77564.1 - 9.9e-24 83.1 18.2 1.7e-23 82.4 12.6 1.4 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EXF77564.1 - 7.4e-18 63.8 1.7 7.4e-18 63.8 1.2 2.0 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Fe-S_biosyn PF01521.15 EXF77565.1 - 2.2e-13 50.1 0.0 4.7e-12 45.8 0.0 2.1 1 1 0 1 1 1 1 Iron-sulphur cluster biosynthesis Herpes_gE PF02480.11 EXF77566.1 - 0.031 12.5 0.0 0.035 12.3 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E RSN1_TM PF13967.1 EXF77566.1 - 0.059 12.9 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport TMEM154 PF15102.1 EXF77566.1 - 0.11 12.1 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 TMEM154 protein family DUF543 PF04418.7 EXF77567.1 - 6.1e-29 99.7 0.0 6.6e-29 99.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) Urb2 PF10441.4 EXF77568.1 - 6e-53 179.7 3.1 6.5e-53 179.6 0.2 2.7 3 0 0 3 3 3 1 Urb2/Npa2 family PI3_PI4_kinase PF00454.22 EXF77569.1 - 9.7e-32 110.3 0.0 1.5e-31 109.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Pik1 PF11522.3 EXF77569.1 - 4e-19 68.0 0.0 8.2e-19 67.0 0.0 1.6 1 0 0 1 1 1 1 Yeast phosphatidylinositol-4-OH kinase Pik1 PI3Ka PF00613.15 EXF77569.1 - 0.19 10.8 0.4 0.35 10.0 0.3 1.4 1 0 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) CBFD_NFYB_HMF PF00808.18 EXF77570.1 - 2.4e-12 46.7 3.0 3.7e-12 46.1 2.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EXF77570.1 - 0.00018 21.5 0.6 0.00027 20.9 0.4 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Gemini_C4 PF01492.12 EXF77570.1 - 0.34 10.6 3.6 14 5.4 0.0 2.9 2 0 0 2 2 2 0 Geminivirus C4 protein DUF2424 PF10340.4 EXF77571.1 - 5.2e-20 71.4 0.0 9.3e-14 50.8 0.0 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF2424) Abhydrolase_3 PF07859.8 EXF77571.1 - 3e-18 66.1 0.0 5.5e-18 65.3 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EXF77571.1 - 0.00032 19.5 0.3 0.19 10.3 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Abhydrolase_5 PF12695.2 EXF77571.1 - 0.02 14.6 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family mRNA_cap_enzyme PF01331.14 EXF77572.1 - 1.8e-53 181.0 1.2 3.1e-53 180.3 0.9 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.10 EXF77572.1 - 2.1e-21 76.2 0.0 3.7e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EXF77572.1 - 5.3e-10 39.0 0.5 3.8e-08 32.9 0.4 2.3 1 1 0 1 1 1 1 ATP dependent DNA ligase domain PX PF00787.19 EXF77573.1 - 1.1e-19 70.3 0.0 3.7e-19 68.5 0.0 2.0 2 0 0 2 2 2 1 PX domain Vps5 PF09325.5 EXF77573.1 - 2.1e-16 59.8 11.1 4.6e-11 42.4 0.2 2.1 2 0 0 2 2 2 2 Vps5 C terminal like TPR_11 PF13414.1 EXF77575.1 - 7.2e-31 105.6 28.0 9.6e-10 37.9 1.5 11.1 9 3 3 12 12 12 6 TPR repeat TPR_1 PF00515.23 EXF77575.1 - 2.6e-30 102.7 16.4 0.00046 19.6 0.2 11.3 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_2 PF07719.12 EXF77575.1 - 3.1e-25 86.0 32.2 0.0012 18.5 0.2 12.3 13 0 0 13 13 12 8 Tetratricopeptide repeat TPR_8 PF13181.1 EXF77575.1 - 6.2e-24 81.9 18.6 0.00024 20.6 0.2 11.3 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_12 PF13424.1 EXF77575.1 - 2.1e-20 72.4 26.2 0.00013 21.8 0.0 10.2 7 4 2 10 10 10 4 Tetratricopeptide repeat TPR_7 PF13176.1 EXF77575.1 - 1.7e-16 58.6 19.2 0.00082 18.9 0.0 10.4 11 0 0 11 11 9 5 Tetratricopeptide repeat TPR_19 PF14559.1 EXF77575.1 - 3.9e-16 59.1 23.2 4.7e-05 23.6 0.0 10.9 9 2 1 10 10 9 3 Tetratricopeptide repeat TPR_17 PF13431.1 EXF77575.1 - 1.3e-10 40.5 9.7 0.05 13.8 0.1 9.9 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_14 PF13428.1 EXF77575.1 - 4.8e-09 36.0 32.8 1.4 9.7 0.0 13.7 13 2 2 16 16 15 2 Tetratricopeptide repeat Apc3 PF12895.2 EXF77575.1 - 7.1e-08 32.4 20.6 0.016 15.3 0.6 7.3 6 1 1 7 7 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EXF77575.1 - 3.4e-06 27.5 45.6 0.044 14.4 0.0 10.7 10 2 1 11 11 9 3 Tetratricopeptide repeat TPR_6 PF13174.1 EXF77575.1 - 3.5e-05 23.9 24.0 0.31 11.5 0.0 11.0 14 1 0 14 14 11 1 Tetratricopeptide repeat TPR_10 PF13374.1 EXF77575.1 - 0.0098 15.7 28.2 0.19 11.6 0.0 8.3 9 0 0 9 9 7 2 Tetratricopeptide repeat SUV3_C PF12513.3 EXF77575.1 - 0.076 12.4 1.5 0.37 10.2 0.0 3.0 4 0 0 4 4 4 0 Mitochondrial degradasome RNA helicase subunit C terminal FAA_hydrolase_N PF09298.6 EXF77575.1 - 0.4 10.7 4.2 1.3 9.0 2.9 1.9 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal TPR_3 PF07720.7 EXF77575.1 - 6.8 6.5 12.7 0.55 10.0 0.1 4.8 6 0 0 6 6 5 0 Tetratricopeptide repeat Alpha-amylase PF00128.19 EXF77576.1 - 1.6e-100 336.5 4.7 1.9e-100 336.3 2.3 1.7 2 0 0 2 2 2 1 Alpha amylase, catalytic domain DUF3459 PF11941.3 EXF77576.1 - 2.3e-05 24.4 0.0 5.8e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3459) hDGE_amylase PF14701.1 EXF77576.1 - 0.013 14.4 0.1 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme CMAS PF02353.15 EXF77577.1 - 2.5e-17 62.8 0.0 4.3e-10 39.1 0.0 3.0 2 1 1 3 3 3 2 Mycolic acid cyclopropane synthetase DUF4495 PF14906.1 EXF77577.1 - 0.062 12.2 0.0 0.098 11.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4495) Herpes_gE PF02480.11 EXF77578.1 - 0.064 11.5 0.0 0.088 11.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E SOG2 PF10428.4 EXF77578.1 - 1.4 7.5 5.3 1.9 7.0 3.7 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Use1 PF09753.4 EXF77580.1 - 3.8e-07 29.8 1.8 7.3e-07 28.8 1.2 1.6 1 1 0 1 1 1 1 Membrane fusion protein Use1 GldM_N PF12081.3 EXF77580.1 - 0.012 15.1 0.9 0.02 14.3 0.6 1.3 1 0 0 1 1 1 0 GldM N-terminal domain DUF605 PF04652.11 EXF77580.1 - 0.11 11.8 16.2 0.15 11.3 11.2 1.1 1 0 0 1 1 1 0 Vta1 like Phage_Gp23 PF10669.4 EXF77580.1 - 5.5 7.1 8.3 0.31 11.1 0.8 2.3 2 1 0 2 2 2 0 Protein gp23 (Bacteriophage A118) RhoGAP PF00620.22 EXF77581.1 - 2.4e-39 134.3 0.0 4.1e-39 133.6 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain DUF290 PF01060.18 EXF77581.1 - 0.22 11.5 0.0 0.42 10.6 0.0 1.4 1 0 0 1 1 1 0 Transthyretin-like family Glyco_transf_22 PF03901.12 EXF77582.1 - 8.6e-81 272.0 4.4 1.8e-80 271.0 3.0 1.5 1 1 0 1 1 1 1 Alg9-like mannosyltransferase family LigD_N PF13298.1 EXF77582.1 - 0.093 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase Ligase (LigD) Aminotran_3 PF00202.16 EXF77583.1 - 3.1e-108 361.6 0.0 3.8e-108 361.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EXF77583.1 - 2.4e-05 23.6 0.0 4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase GTP_cyclohydro2 PF00925.15 EXF77584.1 - 1.1e-57 193.9 0.0 3.9e-55 185.6 0.0 2.1 1 1 0 1 1 1 1 GTP cyclohydrolase II Hexapep PF00132.19 EXF77585.1 - 2.3e-08 33.1 8.2 0.0003 20.1 0.9 4.5 3 1 1 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EXF77585.1 - 8.8e-07 28.3 3.1 0.00013 21.4 1.4 3.1 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Meth_synt_2 PF01717.13 EXF77586.1 - 1.7e-12 46.9 0.0 2.1e-11 43.3 0.0 2.1 1 1 0 1 1 1 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EXF77586.1 - 0.0015 17.9 0.0 0.0064 15.7 0.0 1.9 2 0 0 2 2 2 1 Cobalamin-independent synthase, N-terminal domain F-box-like PF12937.2 EXF77587.1 - 1.9e-07 30.7 4.7 5e-07 29.3 1.9 2.6 2 1 0 2 2 2 1 F-box-like F-box PF00646.28 EXF77587.1 - 0.0038 16.8 0.4 0.12 12.0 0.0 2.7 2 0 0 2 2 2 1 F-box domain PRELI PF04707.9 EXF77588.1 - 2.9e-19 69.1 0.0 6.5e-16 58.2 0.0 2.1 2 0 0 2 2 2 2 PRELI-like family bPH_2 PF03703.9 EXF77588.1 - 0.078 13.0 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 Bacterial PH domain RF-1 PF00472.15 EXF77589.1 - 3.3e-33 113.8 2.1 9.5e-33 112.3 1.5 1.8 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EXF77589.1 - 4.6e-25 87.5 0.0 1.6e-24 85.8 0.0 2.0 2 0 0 2 2 2 1 PCRF domain GST_N_3 PF13417.1 EXF77591.1 - 3.6e-16 59.1 0.0 5.9e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EXF77591.1 - 7.9e-13 48.2 0.0 1.2e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EXF77591.1 - 1.7e-11 44.0 0.0 3.1e-11 43.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EXF77591.1 - 3.1e-06 26.9 3.0 3.6e-06 26.7 1.2 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EXF77591.1 - 0.00076 19.4 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EXF77591.1 - 0.035 14.5 0.1 0.14 12.6 0.0 1.9 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain Ifi-6-16 PF06140.8 EXF77593.1 - 0.0065 16.2 1.8 0.046 13.5 1.3 2.0 1 1 1 2 2 2 1 Interferon-induced 6-16 family Ifi-6-16 PF06140.8 EXF77594.1 - 0.00069 19.3 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Interferon-induced 6-16 family DUF883 PF05957.8 EXF77594.1 - 0.00083 19.7 0.3 0.025 14.9 0.0 2.1 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF883) SHS2_Rpb7-N PF03876.12 EXF77595.1 - 3e-06 27.2 0.0 5.9e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 NmrA PF05368.8 EXF77596.1 - 1.5e-33 116.0 0.2 1.9e-33 115.6 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF77596.1 - 2.3e-09 37.5 0.1 4.5e-09 36.5 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EXF77596.1 - 1.6e-05 23.7 0.1 2.4e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EXF77596.1 - 5.1e-05 22.4 0.2 9.6e-05 21.5 0.1 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EXF77596.1 - 0.00015 22.0 0.2 0.0007 19.8 0.0 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EXF77596.1 - 0.00026 20.4 0.0 0.00043 19.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EXF77596.1 - 0.0014 18.6 0.2 0.0034 17.3 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain PTH2 PF01981.11 EXF77596.1 - 0.0015 18.1 0.1 1.2 8.8 0.0 2.3 2 0 0 2 2 2 2 Peptidyl-tRNA hydrolase PTH2 adh_short PF00106.20 EXF77596.1 - 0.009 15.9 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF77596.1 - 0.0095 15.6 0.1 0.033 13.8 0.0 1.9 2 1 1 3 3 3 1 KR domain Asp_Glu_race PF01177.17 EXF77597.1 - 3.1e-17 63.2 0.0 3.5e-17 63.0 0.0 1.0 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Actin PF00022.14 EXF77598.1 - 6.6e-116 386.9 0.0 7.4e-116 386.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EXF77598.1 - 0.023 13.3 0.0 0.18 10.3 0.0 2.1 1 1 0 1 1 1 0 MreB/Mbl protein Pkinase PF00069.20 EXF77599.1 - 1.8e-61 207.5 0.0 2.3e-61 207.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF77599.1 - 4.6e-31 107.8 0.0 6.9e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF77599.1 - 0.0059 15.6 0.0 0.0093 14.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EXF77599.1 - 0.068 12.9 0.0 0.29 10.8 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ribosomal_S24e PF01282.14 EXF77600.1 - 1.8e-34 117.3 0.0 2.8e-34 116.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e RRXRR PF14239.1 EXF77600.1 - 0.029 13.7 1.0 0.032 13.6 0.7 1.2 1 0 0 1 1 1 0 RRXRR protein Methyltransf_16 PF10294.4 EXF77601.1 - 3.5e-19 68.9 0.0 5.3e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EXF77601.1 - 2.9e-06 27.8 0.0 5.8e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF77601.1 - 0.00046 19.9 0.0 0.0007 19.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF77601.1 - 0.00059 19.2 0.0 0.00095 18.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EXF77601.1 - 0.001 18.2 0.0 0.0015 17.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EXF77601.1 - 0.0016 18.0 0.0 0.0033 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.7 EXF77601.1 - 0.012 16.0 0.0 0.023 15.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 EXF77601.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_26 PF13659.1 EXF77601.1 - 0.064 13.2 0.0 0.12 12.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.12 EXF77601.1 - 0.092 11.7 0.0 0.16 11.0 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase DUF938 PF06080.7 EXF77601.1 - 0.096 12.2 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) Methyltransf_31 PF13847.1 EXF77601.1 - 0.097 12.2 0.1 0.18 11.3 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Activator_LAG-3 PF11498.3 EXF77602.1 - 0.024 13.3 0.4 0.03 13.1 0.3 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Pro_isomerase PF00160.16 EXF77603.1 - 1.5e-35 122.6 0.0 2.5e-35 121.9 0.0 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EXF77603.1 - 1.2e-15 56.8 0.0 2.1e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF77603.1 - 6.4e-11 42.0 0.0 1.3e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF77603.1 - 6.2e-09 35.5 0.1 1.9e-08 34.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Avl9 PF09794.4 EXF77605.1 - 2.8e-146 486.8 0.0 3.5e-146 486.5 0.0 1.1 1 0 0 1 1 1 1 Transport protein Avl9 SPA PF08616.5 EXF77605.1 - 6.1e-08 32.3 0.1 0.00026 20.6 0.0 2.4 2 0 0 2 2 2 2 Stabilization of polarity axis DUF2347 PF09804.4 EXF77605.1 - 2e-07 30.5 1.2 2.3e-06 27.1 0.1 3.1 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) Pkinase PF00069.20 EXF77606.1 - 6.4e-73 245.0 0.0 8.4e-73 244.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF77606.1 - 7.3e-32 110.4 0.0 1e-31 109.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EXF77606.1 - 9.4e-06 24.8 0.1 3.1e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EXF77606.1 - 0.0002 20.4 0.0 0.023 13.6 0.0 2.2 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 EXF77606.1 - 0.00024 20.9 0.1 0.0013 18.5 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EXF77606.1 - 0.019 14.2 0.0 0.035 13.4 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Phosphorylase PF00343.15 EXF77607.1 - 0 1074.8 0.2 0 1074.5 0.2 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Coatomer_b_Cpla PF14806.1 EXF77607.1 - 0.073 12.7 0.0 0.21 11.3 0.0 1.7 1 0 0 1 1 1 0 Coatomer beta subunit appendage platform Methyltransf_23 PF13489.1 EXF77608.1 - 0.029 14.0 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain ABC_tran PF00005.22 EXF77609.1 - 7.1e-48 162.3 0.0 2.3e-23 82.9 0.0 2.7 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EXF77609.1 - 5.5e-21 75.7 0.2 4.9e-05 23.4 0.0 4.3 3 1 0 4 4 4 4 AAA domain ABC_tran_2 PF12848.2 EXF77609.1 - 1.1e-18 66.8 0.7 1.1e-18 66.8 0.5 2.5 2 0 0 2 2 1 1 ABC transporter SMC_N PF02463.14 EXF77609.1 - 6.7e-12 45.1 0.1 0.0002 20.6 0.0 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EXF77609.1 - 7.1e-10 38.2 0.1 0.00086 18.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EXF77609.1 - 1.2e-09 38.8 0.7 0.021 15.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EXF77609.1 - 4.3e-07 30.7 0.0 0.0056 17.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EXF77609.1 - 1.5e-06 27.4 0.0 0.0021 17.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EXF77609.1 - 4.7e-06 26.9 0.1 0.058 13.7 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EXF77609.1 - 5.4e-06 26.5 0.0 0.15 12.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain Miro PF08477.8 EXF77609.1 - 7.8e-06 26.3 0.0 0.027 14.9 0.0 2.6 2 0 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EXF77609.1 - 9.4e-06 25.5 0.0 0.061 13.2 0.0 3.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_28 PF13521.1 EXF77609.1 - 1.4e-05 25.0 0.0 0.021 14.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EXF77609.1 - 2.1e-05 24.5 0.4 0.15 12.0 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EXF77609.1 - 2.2e-05 23.9 0.0 0.3 10.4 0.0 2.7 3 0 0 3 3 3 2 AAA domain NACHT PF05729.7 EXF77609.1 - 2.8e-05 23.8 0.1 0.16 11.6 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA PF00004.24 EXF77609.1 - 3.3e-05 24.0 0.0 0.31 11.2 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EXF77609.1 - 9.5e-05 22.1 0.2 0.45 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EXF77609.1 - 0.00012 21.9 0.0 0.32 10.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EXF77609.1 - 0.00033 20.7 0.0 1.3 9.2 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_15 PF13175.1 EXF77609.1 - 0.00036 19.7 0.0 0.14 11.2 0.0 2.8 4 0 0 4 4 3 1 AAA ATPase domain Arch_ATPase PF01637.13 EXF77609.1 - 0.00046 19.9 0.0 0.26 10.9 0.0 2.7 3 0 0 3 3 2 1 Archaeal ATPase AAA_10 PF12846.2 EXF77609.1 - 0.00062 19.3 0.8 0.96 8.8 0.2 2.9 3 0 0 3 3 3 2 AAA-like domain AAA_14 PF13173.1 EXF77609.1 - 0.0012 18.7 0.0 1.7 8.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 EXF77609.1 - 0.0033 17.2 0.5 3.6 7.3 0.0 3.3 3 1 0 3 3 3 1 Dynamin family SbcCD_C PF13558.1 EXF77609.1 - 0.0033 17.2 0.6 0.46 10.4 0.0 3.7 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.17 EXF77609.1 - 0.0052 15.6 0.1 0.71 8.6 0.0 2.9 2 1 0 2 2 2 1 NB-ARC domain MobB PF03205.9 EXF77609.1 - 0.0055 16.4 0.1 0.27 10.9 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B DUF2813 PF11398.3 EXF77609.1 - 0.0093 15.0 0.0 2.9 6.8 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2813) DAP3 PF10236.4 EXF77609.1 - 0.011 14.6 0.1 2.2 7.1 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 ATP-synt_ab PF00006.20 EXF77609.1 - 0.043 13.3 0.0 0.95 8.9 0.0 2.8 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain NTPase_1 PF03266.10 EXF77609.1 - 0.049 13.3 0.2 7.1 6.3 0.1 2.6 2 0 0 2 2 2 0 NTPase DUF815 PF05673.8 EXF77609.1 - 0.074 11.9 0.1 3.2 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) PduV-EutP PF10662.4 EXF77609.1 - 0.074 12.5 0.5 5.5 6.4 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF3584 PF12128.3 EXF77609.1 - 0.16 9.2 0.7 0.36 8.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) AAA_24 PF13479.1 EXF77609.1 - 0.58 9.7 4.7 9.3 5.7 0.0 3.7 4 0 0 4 4 4 0 AAA domain MARVEL PF01284.18 EXF77610.1 - 0.013 15.3 0.9 2.7 7.7 0.0 2.2 2 0 0 2 2 2 0 Membrane-associating domain Claudin_3 PF06653.6 EXF77610.1 - 0.026 14.2 0.5 0.048 13.3 0.4 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like PrgI PF12666.2 EXF77611.1 - 5.5 7.1 6.3 0.79 9.9 0.8 1.9 2 0 0 2 2 2 0 PrgI family protein GFO_IDH_MocA PF01408.17 EXF77613.1 - 1.6e-25 89.9 0.0 2.8e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EXF77613.1 - 7.3e-16 57.9 0.0 1.5e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Tannase PF07519.6 EXF77616.1 - 2e-87 293.9 0.1 2.5e-87 293.5 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 EXF77616.1 - 0.004 16.3 0.1 1.1 8.3 0.1 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EXF77616.1 - 0.0069 15.9 0.1 0.015 14.8 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EXF77616.1 - 0.01 15.7 0.1 0.034 14.0 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family FMO-like PF00743.14 EXF77617.1 - 2.8e-60 204.0 0.0 4.3e-60 203.4 0.0 1.3 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EXF77617.1 - 2e-25 90.0 0.0 3.8e-23 82.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF77617.1 - 2e-08 34.3 0.0 6.9e-07 29.3 0.0 2.4 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF77617.1 - 1.3e-07 30.9 0.0 4.4e-06 25.8 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EXF77617.1 - 2.6e-07 30.5 0.0 8.8e-05 22.3 0.0 3.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EXF77617.1 - 0.00012 21.1 0.0 0.061 12.2 0.1 3.1 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF77617.1 - 0.00046 20.1 0.0 0.0015 18.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_2 PF03446.10 EXF77617.1 - 0.00054 19.8 0.1 0.018 14.9 0.0 2.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EXF77617.1 - 0.0026 17.1 0.0 0.25 10.7 0.0 2.3 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain ThiF PF00899.16 EXF77617.1 - 0.0039 17.0 1.4 0.31 10.8 0.0 2.6 2 0 0 2 2 2 1 ThiF family UDPG_MGDP_dh_N PF03721.9 EXF77617.1 - 0.0059 16.0 0.4 0.052 12.9 0.1 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.14 EXF77617.1 - 0.0086 15.2 0.1 1 8.4 0.0 2.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.22 EXF77617.1 - 0.016 15.5 0.8 2.3 8.6 0.0 2.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EXF77617.1 - 0.017 15.3 0.0 1.9 8.7 0.0 2.5 2 1 0 2 2 2 0 Putative NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 EXF77617.1 - 0.091 12.4 0.0 1.9 8.1 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.15 EXF77617.1 - 0.11 12.5 0.1 1.7 8.7 0.0 2.6 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EXF77617.1 - 0.18 11.4 0.6 2.2 7.8 0.1 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EXF77617.1 - 0.3 11.0 0.9 4.1 7.4 0.1 2.6 2 0 0 2 2 2 0 TrkA-N domain HET PF06985.6 EXF77618.1 - 4.2e-33 114.4 0.4 6.8e-33 113.7 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 EXF77619.1 - 5.5e-35 120.5 0.3 9.5e-35 119.7 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_4 PF08386.5 EXF77621.1 - 4.4e-18 65.0 0.0 9.2e-18 64.0 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EXF77621.1 - 5.5e-11 42.4 0.0 2.6e-06 27.1 0.0 2.9 2 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EXF77621.1 - 3.8e-06 26.9 0.1 2.4e-05 24.3 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Git3 PF11710.3 EXF77622.1 - 1.6e-09 37.6 0.9 2.9e-09 36.7 0.6 1.5 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EXF77622.1 - 0.00076 19.1 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 EXF77622.1 - 0.0035 16.5 3.1 0.0053 15.9 2.1 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Sugar_tr PF00083.19 EXF77623.1 - 9.5e-57 192.5 25.2 2.8e-53 181.1 17.5 3.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF77623.1 - 1.1e-17 63.8 33.5 4.8e-14 51.8 3.4 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF912 PF06024.7 EXF77625.1 - 0.014 15.4 0.0 0.024 14.6 0.0 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EphA2_TM PF14575.1 EXF77625.1 - 0.017 15.5 0.0 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 EXF77625.1 - 0.079 11.2 0.0 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM154 PF15102.1 EXF77625.1 - 0.089 12.4 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 TMEM154 protein family 7tm_1 PF00001.16 EXF77625.1 - 0.1 11.6 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) YajC PF02699.10 EXF77625.1 - 0.11 12.1 0.1 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Preprotein translocase subunit MSC PF09402.5 EXF77625.1 - 0.12 11.0 0.4 0.17 10.5 0.3 1.1 1 0 0 1 1 1 0 Man1-Src1p-C-terminal domain p450 PF00067.17 EXF77626.1 - 2.2e-56 191.3 0.0 2.8e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.7 EXF77627.1 - 1.3e-09 37.7 0.0 2.7e-09 36.7 0.0 1.6 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF77627.1 - 2.7e-08 33.4 0.0 6.5e-08 32.1 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF77627.1 - 2.6e-07 31.5 0.0 5.5e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EXF77627.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding ADH_N PF08240.7 EXF77628.1 - 9.8e-09 34.9 0.3 2.2e-08 33.8 0.2 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF77628.1 - 2.6e-08 33.4 0.3 5.9e-08 32.3 0.2 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Acyltransferase PF01553.16 EXF77629.1 - 2.2e-26 91.8 0.0 3.1e-26 91.3 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Pkinase PF00069.20 EXF77631.1 - 8.6e-13 48.0 0.0 1.2e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF77631.1 - 0.0019 17.2 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EXF77631.1 - 0.018 14.7 0.0 0.035 13.8 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EXF77631.1 - 0.052 12.4 0.0 0.076 11.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.15 EXF77631.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Sugar_tr PF00083.19 EXF77632.1 - 3.1e-72 243.5 28.7 3.6e-72 243.3 19.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF77632.1 - 4.4e-15 55.2 44.2 1.7e-10 40.1 14.2 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EXF77632.1 - 1.6 7.0 35.7 0.0055 15.1 6.9 3.6 3 1 1 4 4 4 0 MFS/sugar transport protein 5_nucleotid_C PF02872.13 EXF77633.1 - 3.4e-33 114.8 0.3 7.3e-33 113.7 0.2 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.23 EXF77633.1 - 2.7e-12 46.5 0.5 7.1e-10 38.6 0.4 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase YmdB PF13277.1 EXF77633.1 - 0.02 13.9 0.0 0.072 12.1 0.0 1.9 2 0 0 2 2 2 0 YmdB-like protein DUF3288 PF11691.3 EXF77634.1 - 0.1 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3288) EthD PF07110.6 EXF77637.1 - 0.0043 17.9 0.0 0.0081 17.0 0.0 1.5 1 0 0 1 1 1 1 EthD domain Fungal_trans PF04082.13 EXF77638.1 - 3.1e-10 39.3 0.2 5.4e-10 38.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FPN1 PF06963.7 EXF77639.1 - 3.3e-121 404.7 10.7 3.7e-121 404.5 7.4 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) PQ-loop PF04193.9 EXF77640.1 - 8.7e-37 124.4 3.5 2.6e-19 68.4 0.1 2.6 2 0 0 2 2 2 2 PQ loop repeat Exo_endo_phos PF03372.18 EXF77641.1 - 5.1e-10 39.7 0.0 6e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EXF77641.1 - 0.00057 19.4 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase Maf_N PF08383.6 EXF77641.1 - 0.057 12.9 1.2 0.066 12.7 0.0 1.6 2 0 0 2 2 2 0 Maf N-terminal region AbiH PF14253.1 EXF77642.1 - 0.016 14.7 0.3 0.027 14.0 0.2 1.3 1 0 0 1 1 1 0 Bacteriophage abortive infection AbiH Lactonase PF10282.4 EXF77643.1 - 6.2e-82 275.4 0.2 7.7e-82 275.1 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller FAD_binding_4 PF01565.18 EXF77644.1 - 7.3e-19 67.6 0.4 2.3e-18 66.0 0.3 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EXF77644.1 - 1.9e-08 34.0 0.8 4.4e-08 32.9 0.6 1.6 1 0 0 1 1 1 1 Berberine and berberine like Acyl_transf_1 PF00698.16 EXF77645.1 - 2.3e-65 221.0 0.2 3.4e-65 220.4 0.2 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 EXF77645.1 - 2.5e-59 200.8 0.0 5.6e-59 199.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PS-DH PF14765.1 EXF77645.1 - 3.3e-55 187.3 0.0 9.5e-55 185.8 0.0 1.9 2 0 0 2 2 2 1 Polyketide synthase dehydratase KR PF08659.5 EXF77645.1 - 3.1e-54 183.3 0.2 3.1e-54 183.3 0.1 1.9 2 0 0 2 2 1 1 KR domain NAD_kinase PF01513.16 EXF77645.1 - 1.8e-47 161.4 0.0 4.7e-47 160.1 0.0 1.6 1 0 0 1 1 1 1 ATP-NAD kinase adh_short PF00106.20 EXF77645.1 - 1.8e-44 151.6 0.3 1.8e-44 151.6 0.2 2.2 2 0 0 2 2 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EXF77645.1 - 8.4e-30 103.0 0.2 8.4e-30 103.0 0.2 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EXF77645.1 - 3e-18 66.1 0.0 6.8e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EXF77645.1 - 1.4e-17 63.4 0.1 4.5e-17 61.8 0.1 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF77645.1 - 1.2e-11 45.6 0.0 4.5e-11 43.7 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EXF77645.1 - 1.8e-11 44.0 0.0 4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF77645.1 - 2.3e-08 34.5 0.0 7.2e-08 32.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EXF77645.1 - 4.6e-08 32.8 0.4 9.6e-08 31.7 0.3 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.1 EXF77645.1 - 4.8e-08 32.7 0.0 9.8e-08 31.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF77645.1 - 2.3e-06 28.0 0.0 5.2e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EXF77645.1 - 0.00068 18.7 0.1 0.0023 16.9 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 EXF77645.1 - 0.0016 17.6 0.0 0.0034 16.5 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ACP_syn_III PF08545.5 EXF77645.1 - 0.024 14.2 0.5 0.064 12.9 0.3 1.7 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_28 PF02636.12 EXF77645.1 - 0.066 12.6 0.0 2.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.4 EXF77645.1 - 0.15 11.4 0.0 0.58 9.5 0.0 1.9 1 1 0 1 1 1 0 Putative methyltransferase DREV PF05219.7 EXF77645.1 - 0.53 9.1 0.0 1 8.1 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase DUF3328 PF11807.3 EXF77646.1 - 6e-22 78.3 0.6 1.2e-21 77.4 0.4 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EXF77647.1 - 0.072 12.7 2.8 0.09 12.4 1.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) PAP1 PF08601.5 EXF77647.1 - 0.095 12.3 0.7 0.11 12.1 0.0 1.4 2 0 0 2 2 2 0 Transcription factor PAP1 Thioesterase PF00975.15 EXF77648.1 - 2.2e-14 54.2 0.0 3.8e-14 53.4 0.0 1.4 1 1 0 1 1 1 1 Thioesterase domain Abhydrolase_6 PF12697.2 EXF77648.1 - 2.3e-09 37.4 0.2 3.8e-09 36.7 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EXF77648.1 - 0.00073 19.1 0.0 0.001 18.7 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF77648.1 - 0.0012 18.5 0.0 0.0017 18.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EXF77648.1 - 0.015 14.7 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.15 EXF77648.1 - 0.018 14.6 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2235 PF09994.4 EXF77648.1 - 0.081 12.2 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Lipase_3 PF01764.20 EXF77648.1 - 0.1 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.11 EXF77648.1 - 0.12 11.7 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase HTH_16 PF12645.2 EXF77648.1 - 0.17 11.8 0.0 17 5.3 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain DUF3328 PF11807.3 EXF77649.1 - 8.4e-19 68.1 0.0 1.2e-18 67.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF4119 PF13494.1 EXF77651.1 - 0.0017 18.2 3.2 2.4 8.1 0.1 4.3 1 1 3 4 4 4 2 Domain of unknown function, B. Theta Gene description (DUF4119) Toxin_59 PF15537.1 EXF77651.1 - 0.35 10.9 1.9 29 4.7 0.0 3.1 1 1 3 4 4 4 0 Putative toxin 59 MFS_1 PF07690.11 EXF77654.1 - 1.9e-24 86.0 29.2 3.9e-18 65.2 7.0 3.0 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF1228 PF06779.9 EXF77654.1 - 0.00076 19.4 2.5 0.12 12.3 0.1 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF1228) OATP PF03137.15 EXF77654.1 - 0.06 11.3 3.7 0.89 7.5 0.6 2.7 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family PIRT PF15099.1 EXF77654.1 - 1 8.5 3.5 22 4.2 1.1 2.9 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family Methyltransf_12 PF08242.7 EXF77655.1 - 7.1e-17 61.7 0.0 1.7e-16 60.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF77655.1 - 2.9e-10 40.4 0.0 5.2e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF77655.1 - 8.8e-09 35.2 0.0 1.9e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF77655.1 - 1.2e-08 34.7 0.0 1.8e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF77655.1 - 7e-07 29.8 0.0 1.7e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF77655.1 - 1.5e-05 24.2 0.0 0.00022 20.4 0.0 2.3 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EXF77655.1 - 0.0003 21.1 0.0 0.0007 19.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF77655.1 - 0.0045 16.9 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 EXF77655.1 - 0.012 15.1 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) NNMT_PNMT_TEMT PF01234.12 EXF77655.1 - 0.14 11.0 0.0 3.8 6.4 0.0 2.1 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family ADH_zinc_N PF00107.21 EXF77656.1 - 6.7e-13 48.3 0.1 1.4e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF77656.1 - 1.6e-09 37.4 0.8 1.8e-08 34.1 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain PS-DH PF14765.1 EXF77657.1 - 6.8e-59 199.4 0.0 1e-58 198.8 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.21 EXF77657.1 - 7.4e-58 196.0 0.0 3.1e-57 193.9 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EXF77657.1 - 1.1e-57 195.8 0.0 1.8e-57 195.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EXF77657.1 - 5.8e-51 172.7 0.0 2e-50 170.9 0.0 2.0 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EXF77657.1 - 4.1e-42 143.9 0.0 2e-41 141.6 0.0 2.3 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EXF77657.1 - 8.3e-32 109.5 0.0 3.3e-31 107.5 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EXF77657.1 - 8.9e-06 25.8 0.2 3.4e-05 24.0 0.1 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EXF77657.1 - 0.002 17.1 0.2 0.0041 16.1 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EXF77657.1 - 0.057 13.0 1.2 0.15 11.7 0.8 1.6 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FTCD PF02971.9 EXF77657.1 - 0.24 11.0 0.0 0.52 9.9 0.0 1.5 1 0 0 1 1 1 0 Formiminotransferase domain EamA PF00892.15 EXF77658.1 - 8.1e-15 54.9 31.9 1.4e-09 38.0 5.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family Creatinase_N PF01321.13 EXF77658.1 - 0.086 13.3 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Creatinase/Prolidase N-terminal domain p450 PF00067.17 EXF77659.1 - 2.3e-32 112.1 0.0 3.3e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Zn_clus PF00172.13 EXF77660.1 - 6.7e-10 38.7 6.4 1.7e-09 37.4 4.4 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF77660.1 - 0.011 14.6 0.8 0.02 13.7 0.1 1.8 2 0 0 2 2 2 0 Fungal specific transcription factor domain Herpes_UL51 PF04540.8 EXF77660.1 - 0.017 14.7 0.1 0.038 13.5 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus UL51 protein Peptidase_A8 PF01252.13 EXF77660.1 - 0.078 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Signal peptidase (SPase) II DUF2976 PF11190.3 EXF77660.1 - 0.087 12.3 0.0 11 5.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Methyltransf_12 PF08242.7 EXF77661.1 - 4.4e-06 27.0 0.0 9.4e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF77661.1 - 4e-05 24.0 0.0 0.00015 22.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF77661.1 - 0.0041 17.6 0.0 0.019 15.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF77661.1 - 0.14 12.4 0.0 0.39 11.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Peptidase_S41 PF03572.13 EXF77662.1 - 5.8e-09 35.5 0.0 1.1e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 Alpha-amylase PF00128.19 EXF77663.1 - 6.8e-29 101.2 5.8 1.8e-28 99.8 4.0 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EXF77663.1 - 0.00023 19.0 0.2 0.1 10.3 0.0 2.9 3 0 0 3 3 3 2 Glycosyl hydrolase family 70 AMP-binding PF00501.23 EXF77664.1 - 8.5e-157 521.8 0.0 1.5e-78 264.0 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EXF77664.1 - 4.3e-122 406.6 1.1 4.9e-47 160.2 0.0 4.6 4 1 0 4 4 4 3 Condensation domain PP-binding PF00550.20 EXF77664.1 - 6.6e-33 112.7 0.0 2.5e-11 43.6 0.0 4.2 3 0 0 3 3 3 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EXF77664.1 - 1.7e-05 25.6 0.0 0.044 14.7 0.0 3.2 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain HxxPF_rpt PF13745.1 EXF77664.1 - 0.0011 19.2 0.3 0.82 10.0 0.0 3.8 3 0 0 3 3 3 1 HxxPF-repeated domain AATase PF07247.7 EXF77664.1 - 0.0029 16.2 1.4 2.6 6.4 0.0 3.6 4 1 0 4 4 4 2 Alcohol acetyltransferase SrfB PF07520.6 EXF77664.1 - 0.013 13.0 0.0 0.08 10.4 0.0 1.9 2 0 0 2 2 2 0 Virulence factor SrfB O-FucT PF10250.4 EXF77665.1 - 0.0007 18.8 0.0 0.017 14.2 0.0 2.3 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Hjc PF01870.13 EXF77665.1 - 0.077 12.6 0.0 0.18 11.4 0.0 1.6 1 0 0 1 1 1 0 Archaeal holliday junction resolvase (hjc) DUF3328 PF11807.3 EXF77666.1 - 0.0009 18.9 1.1 0.15 11.7 0.3 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3328) GMC_oxred_N PF00732.14 EXF77667.1 - 2e-28 99.4 0.0 5.4e-28 98.0 0.0 1.8 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF77667.1 - 2.7e-19 69.8 0.2 2.7e-19 69.8 0.1 1.9 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EXF77667.1 - 9.2e-09 34.6 2.6 1.2e-07 30.9 1.8 2.1 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF77667.1 - 3.6e-08 32.7 0.2 5.8e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF77667.1 - 6.1e-08 32.7 0.2 1.5e-05 24.9 0.2 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF77667.1 - 2e-07 29.8 1.3 6.3e-07 28.2 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.2 EXF77667.1 - 1.3e-06 27.7 1.2 2.4e-06 26.9 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EXF77667.1 - 4.3e-06 26.0 0.4 8.7e-06 25.0 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EXF77667.1 - 7.9e-05 22.6 0.1 7.9e-05 22.6 0.1 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EXF77667.1 - 9.7e-05 21.5 0.1 0.00017 20.7 0.1 1.3 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EXF77667.1 - 0.00012 21.0 0.0 0.00026 19.9 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EXF77667.1 - 0.00041 20.4 1.1 0.11 12.5 0.1 2.8 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF77667.1 - 0.00044 19.2 0.6 0.00083 18.3 0.4 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox PF00070.22 EXF77667.1 - 0.0027 18.0 0.0 0.0075 16.6 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EXF77667.1 - 0.011 14.3 0.2 0.02 13.5 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EXF77667.1 - 0.14 11.9 0.9 0.3 10.8 0.2 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding GMC_oxred_N PF00732.14 EXF77668.1 - 4.5e-53 180.3 0.1 6e-53 179.9 0.1 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF77668.1 - 6.4e-40 136.7 0.0 1.4e-39 135.6 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EXF77668.1 - 1.8e-06 27.1 0.1 0.00078 18.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF77668.1 - 0.00011 21.2 0.0 0.00018 20.5 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EXF77668.1 - 0.013 15.5 0.5 0.051 13.6 0.4 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF77668.1 - 0.013 15.3 0.0 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF77668.1 - 0.015 15.3 0.1 0.4 10.7 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF77668.1 - 0.076 11.8 0.2 0.12 11.1 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Fungal_trans_2 PF11951.3 EXF77670.1 - 7.1e-21 74.2 1.0 1.1e-20 73.6 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF77670.1 - 2.5e-05 24.1 8.1 4.7e-05 23.2 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF77671.1 - 2e-07 30.1 0.0 3.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF77671.1 - 3.7e-05 23.5 8.9 7.5e-05 22.5 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CAP PF00188.21 EXF77672.1 - 5.2e-19 68.9 0.3 7.4e-19 68.4 0.2 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PhaG_MnhG_YufB PF03334.9 EXF77672.1 - 0.0033 17.4 1.4 0.0064 16.5 1.0 1.5 1 0 0 1 1 1 1 Na+/H+ antiporter subunit Tubulin PF00091.20 EXF77673.1 - 1.7e-73 247.0 0.0 3.2e-73 246.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EXF77673.1 - 9.1e-43 145.3 0.1 1.4e-42 144.6 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EXF77673.1 - 1.4e-07 31.5 0.0 2.9e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EXF77673.1 - 0.0057 16.1 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain HET PF06985.6 EXF77674.1 - 2.4e-23 82.8 0.3 4.8e-23 81.8 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2207 PF09972.4 EXF77675.1 - 0.086 11.4 2.3 0.1 11.1 1.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Wzy_C PF04932.10 EXF77675.1 - 0.26 11.0 5.2 0.23 11.2 2.8 1.6 2 0 0 2 2 2 0 O-Antigen ligase Fungal_trans_2 PF11951.3 EXF77676.1 - 1.7e-10 40.0 0.4 3e-10 39.2 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF77676.1 - 8.9e-08 31.9 12.4 1.5e-07 31.1 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF500 PF04366.7 EXF77677.1 - 6.9e-36 122.4 0.0 1.1e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) AAA PF00004.24 EXF77678.1 - 4.6e-41 140.1 0.0 8.3e-41 139.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EXF77678.1 - 1e-06 28.9 0.1 0.0003 20.9 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EXF77678.1 - 4e-06 26.8 0.0 8.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EXF77678.1 - 1.3e-05 24.2 0.0 2.2e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EXF77678.1 - 8.7e-05 22.2 0.1 0.0003 20.5 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EXF77678.1 - 0.00035 20.5 0.1 0.0014 18.6 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EXF77678.1 - 0.00049 19.2 0.0 0.0009 18.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_28 PF13521.1 EXF77678.1 - 0.0016 18.4 0.2 0.0048 16.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EXF77678.1 - 0.004 17.0 0.0 0.0072 16.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EXF77678.1 - 0.0045 17.8 0.2 0.013 16.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EXF77678.1 - 0.0067 16.1 0.3 0.016 14.9 0.2 1.5 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EXF77678.1 - 0.0069 15.8 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EXF77678.1 - 0.0098 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EXF77678.1 - 0.01 14.9 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_3 PF07726.6 EXF77678.1 - 0.012 15.1 0.0 0.027 14.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EXF77678.1 - 0.013 15.8 0.0 0.027 14.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EXF77678.1 - 0.013 14.7 1.6 0.21 10.8 0.1 2.2 2 0 0 2 2 2 0 PhoH-like protein NACHT PF05729.7 EXF77678.1 - 0.018 14.7 0.1 0.33 10.5 0.0 2.5 2 1 1 3 3 2 0 NACHT domain TIP49 PF06068.8 EXF77678.1 - 0.02 13.6 0.0 0.043 12.5 0.0 1.5 1 0 0 1 1 1 0 TIP49 C-terminus AAA_25 PF13481.1 EXF77678.1 - 0.023 14.0 1.4 0.24 10.7 0.3 2.4 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.17 EXF77678.1 - 0.038 12.8 0.0 0.062 12.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EXF77678.1 - 0.046 13.9 0.0 0.088 12.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.1 EXF77678.1 - 0.051 13.1 0.2 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EXF77678.1 - 0.054 12.6 0.1 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EXF77678.1 - 0.077 12.1 0.1 0.42 9.6 0.1 2.0 1 1 1 2 2 2 0 KaiC DUF2075 PF09848.4 EXF77678.1 - 0.14 11.0 0.0 0.2 10.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) UQ_con PF00179.21 EXF77679.1 - 1.2e-39 134.8 0.0 1.7e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA_3 PF09288.5 EXF77679.1 - 7.6e-06 25.4 0.1 1.6e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain CoA_binding PF02629.14 EXF77680.1 - 3.9e-24 84.9 2.8 4.6e-22 78.3 0.1 3.2 3 0 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.14 EXF77680.1 - 6.4e-23 81.0 0.2 1.1e-22 80.2 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EXF77680.1 - 3.8e-09 36.2 0.0 6.5e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EXF77680.1 - 0.00012 22.1 0.1 0.00047 20.2 0.0 2.0 3 0 0 3 3 3 1 CoA binding domain GFO_IDH_MocA PF01408.17 EXF77680.1 - 0.025 15.0 0.0 0.058 13.9 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold ATP-synt_J PF04911.7 EXF77681.1 - 0.068 12.6 0.1 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 ATP synthase j chain Pept_tRNA_hydro PF01195.14 EXF77682.1 - 4.1e-27 94.8 0.0 4.7e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase BAR PF03114.13 EXF77683.1 - 4.6e-64 216.0 4.8 6.4e-64 215.5 3.4 1.2 1 0 0 1 1 1 1 BAR domain CP12 PF02672.10 EXF77683.1 - 0.071 13.5 0.7 0.3 11.5 0.0 2.4 3 0 0 3 3 3 0 CP12 domain FliD_N PF02465.13 EXF77683.1 - 4 7.8 5.4 2.7 8.4 0.2 2.5 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DCP1 PF06058.8 EXF77684.1 - 6e-16 58.6 0.0 8.4e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Dcp1-like decapping family Exo_endo_phos PF03372.18 EXF77685.1 - 1.4e-13 51.3 0.8 2.7e-13 50.4 0.5 1.5 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 EXF77685.1 - 0.088 12.4 0.0 0.22 11.1 0.0 1.6 1 0 0 1 1 1 0 RhoGAP domain Methyltransf_23 PF13489.1 EXF77686.1 - 5.7e-18 65.1 0.0 8.5e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF77686.1 - 2.2e-07 30.6 0.0 1.3e-06 28.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF77686.1 - 2.2e-07 31.4 0.0 3.2e-06 27.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF77686.1 - 7.9e-07 29.4 0.0 6.9e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF77686.1 - 1.1e-06 29.0 0.0 3.1e-06 27.5 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.9 EXF77686.1 - 0.0016 17.8 0.0 0.0035 16.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 EXF77686.1 - 0.052 13.5 0.1 0.096 12.6 0.1 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 EXF77686.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) F-box-like PF12937.2 EXF77687.1 - 9.1e-06 25.3 0.0 3.4e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 F-box-like PA28_alpha PF02251.13 EXF77687.1 - 0.12 12.6 0.5 0.79 9.9 0.2 2.4 3 0 0 3 3 3 0 Proteasome activator pa28 alpha subunit F-box-like PF12937.2 EXF77688.1 - 3.2e-06 26.7 0.1 1.4e-05 24.7 0.1 2.2 1 0 0 1 1 1 1 F-box-like CrtC PF07143.6 EXF77689.1 - 1.5e-16 60.6 1.4 5.6e-16 58.7 0.9 1.9 1 1 0 1 1 1 1 Hydroxyneurosporene synthase (CrtC) Abhydrolase_5 PF12695.2 EXF77690.1 - 9.7e-21 74.0 0.0 1.4e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF77690.1 - 2.9e-16 60.0 0.0 1.7e-14 54.2 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF77690.1 - 5.9e-07 29.2 0.0 0.00019 21.0 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 EXF77690.1 - 6.6e-06 24.8 0.0 0.0065 15.0 0.0 3.0 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) DUF818 PF05677.7 EXF77690.1 - 0.00089 18.0 0.0 0.0013 17.5 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.11 EXF77690.1 - 0.00094 18.6 0.0 0.47 9.8 0.0 2.3 1 1 1 2 2 2 2 Phospholipase/Carboxylesterase FSH1 PF03959.8 EXF77690.1 - 0.001 18.5 0.0 0.0033 16.9 0.0 1.7 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Peptidase_S9 PF00326.16 EXF77690.1 - 0.0013 17.9 0.0 0.0082 15.3 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.8 EXF77690.1 - 0.0033 17.0 0.0 0.0059 16.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 EXF77690.1 - 0.017 14.3 0.0 0.38 9.9 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S15 PF02129.13 EXF77690.1 - 0.026 13.9 0.0 5.4 6.3 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 EXF77690.1 - 0.033 13.8 0.0 0.71 9.5 0.0 2.3 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.3 EXF77690.1 - 0.052 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase PGAP1 PF07819.8 EXF77690.1 - 0.14 11.7 0.2 0.44 10.0 0.2 1.9 1 1 0 1 1 1 0 PGAP1-like protein Pex2_Pex12 PF04757.9 EXF77692.1 - 1.3e-39 135.9 2.1 1.8e-39 135.5 1.5 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EXF77692.1 - 9.3e-12 44.5 8.6 1.4e-11 43.9 5.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EXF77692.1 - 2.6e-11 43.3 8.1 4e-11 42.7 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EXF77692.1 - 4.6e-10 38.9 6.9 7e-10 38.4 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EXF77692.1 - 1.6e-09 37.2 6.0 2.5e-09 36.6 4.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EXF77692.1 - 4.9e-08 32.5 5.9 7.5e-08 31.9 4.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EXF77692.1 - 2.6e-06 27.1 8.0 4.2e-06 26.5 5.6 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EXF77692.1 - 9.3e-05 22.1 3.0 0.00017 21.2 2.1 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EXF77692.1 - 0.00012 22.1 6.7 0.00026 21.0 4.7 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger DUF3773 PF12608.3 EXF77692.1 - 0.0013 18.7 0.0 0.84 9.7 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3773) zf-RING_UBOX PF13445.1 EXF77692.1 - 0.0017 17.9 5.0 0.0038 16.9 3.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 EXF77692.1 - 0.0067 15.9 1.6 0.013 14.9 1.1 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EXF77692.1 - 0.055 13.0 8.0 0.1 12.2 5.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EXF77692.1 - 0.086 12.6 2.5 0.15 11.9 1.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TerY-C PF15616.1 EXF77692.1 - 0.11 12.4 1.9 0.19 11.6 1.3 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain IBR PF01485.16 EXF77692.1 - 1.9 8.4 7.0 5.2 7.0 4.9 1.7 1 1 0 1 1 1 0 IBR domain CN_hydrolase PF00795.17 EXF77693.1 - 5.1e-27 94.4 0.0 9.7e-27 93.5 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.12 EXF77693.1 - 1.4e-22 79.7 0.0 8.2e-22 77.2 0.0 2.0 1 1 0 1 1 1 1 NAD synthase Dioxygenase_C PF00775.16 EXF77694.1 - 2.9e-08 33.1 0.0 5.5e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Dioxygenase WSC PF01822.14 EXF77695.1 - 2.7e-87 286.7 85.9 6.8e-18 64.3 11.1 5.8 5 0 0 5 5 5 5 WSC domain Glyoxal_oxid_N PF07250.6 EXF77695.1 - 1.6e-25 89.5 0.0 1.4e-24 86.5 0.0 2.5 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus DUF1929 PF09118.6 EXF77695.1 - 1e-21 76.8 0.0 2.4e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.10 EXF77695.1 - 0.009 15.7 0.0 5.2 6.9 0.2 4.0 2 1 1 3 3 3 2 Kelch motif NACHT PF05729.7 EXF77696.1 - 6.3e-11 42.2 0.1 4.6e-05 23.1 0.0 3.0 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 EXF77696.1 - 2.2e-05 24.6 0.0 0.0001 22.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EXF77696.1 - 2.7e-05 24.4 0.0 0.0023 18.2 0.0 2.7 2 1 0 2 2 2 1 ABC transporter AAA_23 PF13476.1 EXF77696.1 - 0.00026 21.3 0.1 0.0059 16.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EXF77696.1 - 0.0027 17.2 0.1 0.029 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_17 PF13207.1 EXF77696.1 - 0.0034 18.1 0.0 0.071 13.9 0.0 3.1 2 0 0 2 2 2 1 AAA domain Ank_4 PF13637.1 EXF77696.1 - 0.005 17.3 0.0 0.85 10.2 0.0 3.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) AAA_30 PF13604.1 EXF77696.1 - 0.0063 16.1 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Ank_2 PF12796.2 EXF77696.1 - 0.0076 16.5 0.0 0.27 11.5 0.0 2.9 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) AAA_18 PF13238.1 EXF77696.1 - 0.0098 16.1 0.0 0.6 10.4 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.1 EXF77696.1 - 0.011 15.2 0.1 0.03 13.8 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EXF77696.1 - 0.03 14.3 0.1 0.28 11.1 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.12 EXF77696.1 - 0.03 14.1 0.4 0.68 9.7 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF87 RNA_helicase PF00910.17 EXF77696.1 - 0.065 13.4 0.1 0.21 11.7 0.0 1.9 2 0 0 2 2 1 0 RNA helicase AAA_33 PF13671.1 EXF77696.1 - 0.073 12.9 0.4 1.2 8.9 0.0 3.2 4 0 0 4 4 2 0 AAA domain AAA PF00004.24 EXF77696.1 - 0.081 13.1 0.5 1.4 9.0 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EXF77696.1 - 0.1 11.8 0.0 0.23 10.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EXF77696.1 - 0.13 12.2 0.0 0.4 10.6 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase KAP_NTPase PF07693.9 EXF77696.1 - 0.67 8.8 2.9 7.7 5.3 0.1 2.9 2 1 0 2 2 2 0 KAP family P-loop domain Lipase_GDSL_2 PF13472.1 EXF77697.1 - 9.9e-07 29.0 0.6 2e-06 28.0 0.4 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EXF77697.1 - 6.7e-06 26.0 6.9 6.1e-05 22.9 4.8 2.3 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EXF77697.1 - 0.013 15.2 0.1 1.3 8.7 0.0 2.2 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Zip PF02535.17 EXF77698.1 - 0.09 11.7 1.1 0.077 11.9 0.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Pox_A_type_inc PF04508.7 EXF77698.1 - 0.15 11.9 2.6 0.33 10.8 0.1 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat UreE_C PF05194.7 EXF77698.1 - 0.27 11.3 14.1 0.88 9.7 9.8 2.1 1 1 0 1 1 1 0 UreE urease accessory protein, C-terminal domain CENP-F_leu_zip PF10473.4 EXF77698.1 - 0.73 9.6 4.0 6.5 6.6 0.3 2.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ABC_tran PF00005.22 EXF77699.1 - 1e-42 145.6 0.0 3.4e-20 72.7 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EXF77699.1 - 1.7e-35 122.7 27.0 3.3e-24 85.7 6.4 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.14 EXF77699.1 - 1.1e-11 44.4 0.0 0.037 13.2 0.0 4.2 3 1 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EXF77699.1 - 5.6e-11 42.9 0.0 0.25 11.2 0.0 4.3 3 1 1 4 4 4 3 AAA domain DUF258 PF03193.11 EXF77699.1 - 2.4e-08 33.3 1.5 0.00063 18.9 0.3 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EXF77699.1 - 1.1e-06 28.7 1.8 0.0084 16.1 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EXF77699.1 - 4.4e-06 26.8 0.4 0.0059 16.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EXF77699.1 - 1e-05 25.4 0.0 0.048 13.6 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase SbcCD_C PF13558.1 EXF77699.1 - 1.3e-05 25.0 0.1 0.044 13.7 0.0 2.8 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Miro PF08477.8 EXF77699.1 - 2.6e-05 24.6 0.3 0.25 11.8 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EXF77699.1 - 4.5e-05 22.9 0.9 0.15 11.6 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain NB-ARC PF00931.17 EXF77699.1 - 0.0004 19.3 0.1 0.0073 15.2 0.0 2.3 2 0 0 2 2 2 1 NB-ARC domain Dynamin_N PF00350.18 EXF77699.1 - 0.00088 19.1 0.7 0.027 14.2 0.0 2.3 2 0 0 2 2 2 1 Dynamin family AAA_25 PF13481.1 EXF77699.1 - 0.0045 16.3 2.6 0.25 10.7 0.0 2.8 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EXF77699.1 - 0.0048 16.6 0.1 0.39 10.3 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase DUF815 PF05673.8 EXF77699.1 - 0.0081 15.1 1.4 0.24 10.2 0.2 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 EXF77699.1 - 0.012 15.1 0.2 0.31 10.5 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EXF77699.1 - 0.017 14.2 0.3 0.29 10.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 EXF77699.1 - 0.019 15.7 0.1 2.2 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EXF77699.1 - 0.025 14.7 0.1 0.38 10.9 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EXF77699.1 - 0.038 13.6 0.2 5.8 6.5 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.1 EXF77699.1 - 0.11 12.8 0.2 15 5.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EXF77699.1 - 0.14 11.6 2.6 5 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA-like domain AAA_33 PF13671.1 EXF77699.1 - 0.16 11.8 0.3 20 5.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Adeno_IVa2 PF02456.10 EXF77699.1 - 0.18 10.3 0.1 0.91 8.1 0.0 2.0 2 0 0 2 2 2 0 Adenovirus IVa2 protein PduV-EutP PF10662.4 EXF77699.1 - 0.27 10.6 2.1 0.66 9.4 0.2 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 EXF77699.1 - 0.54 9.9 2.8 14 5.4 0.1 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.1 EXF77699.1 - 0.58 9.1 0.1 3.6 6.5 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain cobW PF02492.14 EXF77699.1 - 0.69 9.3 3.7 16 4.9 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 EXF77699.1 - 1 9.0 3.6 1.1 8.9 0.2 2.5 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 TPR_12 PF13424.1 EXF77700.1 - 0.011 15.6 0.1 1.6 8.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EXF77700.1 - 7.4 7.5 7.4 1.8 9.4 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat ThiF PF00899.16 EXF77701.1 - 1.8e-34 118.5 0.0 3.1e-34 117.6 0.0 1.4 1 0 0 1 1 1 1 ThiF family Saccharop_dh PF03435.13 EXF77701.1 - 1.8e-05 23.9 0.1 2.6e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase MAF_flag10 PF01973.13 EXF77701.1 - 0.00085 18.8 0.0 0.0063 16.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function DUF115 NAD_binding_7 PF13241.1 EXF77701.1 - 0.0072 16.5 0.1 0.021 15.0 0.0 1.8 2 0 0 2 2 2 1 Putative NAD(P)-binding DUF3186 PF11382.3 EXF77701.1 - 0.0097 15.0 0.1 0.018 14.1 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3186) TrkA_N PF02254.13 EXF77701.1 - 0.038 13.9 1.0 0.095 12.7 0.1 2.2 3 0 0 3 3 3 0 TrkA-N domain ApbA PF02558.11 EXF77701.1 - 0.059 12.8 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_17 PF00332.13 EXF77701.1 - 0.08 11.9 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 Arb2 PF09757.4 EXF77702.1 - 5.1e-18 65.1 0.0 8.4e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Arb2 domain Ribosomal_S14 PF00253.16 EXF77703.1 - 2.3e-18 65.3 0.8 1.7e-17 62.5 0.3 2.0 2 0 0 2 2 2 1 Ribosomal protein S14p/S29e Isy1 PF06246.7 EXF77704.1 - 1.8e-87 292.9 0.6 2.8e-87 292.3 0.4 1.3 1 1 0 1 1 1 1 Isy1-like splicing family YebG PF07130.7 EXF77704.1 - 0.023 14.3 0.3 0.051 13.2 0.2 1.6 1 0 0 1 1 1 0 YebG protein CCDC-167 PF15188.1 EXF77704.1 - 0.053 13.4 0.1 0.34 10.8 0.0 2.1 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 YolD PF08863.5 EXF77704.1 - 0.055 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 YolD-like protein DUF1620 PF07774.8 EXF77705.1 - 3.6e-68 229.0 0.0 5.8e-68 228.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EXF77705.1 - 4.1e-13 49.3 8.4 8e-12 45.1 1.8 3.1 3 0 0 3 3 3 2 PQQ-like domain UPF0231 PF06062.6 EXF77705.1 - 0.098 12.5 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0231) HIN PF02760.10 EXF77705.1 - 0.12 11.7 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 HIN-200/IF120x domain PQQ PF01011.16 EXF77705.1 - 0.35 10.4 4.6 10 5.8 0.0 4.0 4 0 0 4 4 4 0 PQQ enzyme repeat EST1_DNA_bind PF10373.4 EXF77706.1 - 1.2e-14 54.2 0.1 1.9e-14 53.5 0.1 1.4 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain 2-Hacid_dh_C PF02826.14 EXF77708.1 - 2.2e-44 150.7 0.0 3.7e-44 149.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EXF77708.1 - 2.5e-05 23.7 0.0 0.00065 19.1 0.0 2.0 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 EXF77708.1 - 0.002 18.0 0.0 0.026 14.3 0.0 2.1 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain XdhC_C PF13478.1 EXF77708.1 - 0.0085 16.4 0.0 0.052 13.8 0.0 2.0 2 0 0 2 2 2 1 XdhC Rossmann domain NAD_binding_7 PF13241.1 EXF77708.1 - 0.021 15.0 0.0 0.076 13.2 0.0 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_10 PF13460.1 EXF77708.1 - 0.087 12.8 0.4 0.22 11.5 0.1 1.8 2 0 0 2 2 2 0 NADH(P)-binding ELFV_dehydrog PF00208.16 EXF77708.1 - 0.089 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Glyco_hydro_47 PF01532.15 EXF77709.1 - 6.9e-154 512.8 0.0 8.4e-154 512.5 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4038 PF13204.1 EXF77709.1 - 0.015 14.6 0.0 0.032 13.5 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4038) SKG6 PF08693.5 EXF77710.1 - 4.5e-07 29.0 1.4 1.6e-06 27.2 1.0 2.0 1 0 0 1 1 1 1 Transmembrane alpha-helix domain ATP_synt_I PF03899.10 EXF77710.1 - 0.029 14.5 0.0 0.067 13.3 0.0 1.5 1 0 0 1 1 1 0 ATP synthase I chain DUF4381 PF14316.1 EXF77710.1 - 0.032 14.3 0.0 0.067 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF1049 PF06305.6 EXF77710.1 - 0.039 13.4 0.1 0.073 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) APH PF01636.18 EXF77711.1 - 5.7e-24 85.1 0.6 8.2e-24 84.6 0.4 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EXF77711.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase PH PF00169.24 EXF77712.1 - 0.0057 16.8 0.2 0.015 15.4 0.0 1.8 2 0 0 2 2 2 1 PH domain SAM_2 PF07647.12 EXF77712.1 - 0.012 15.4 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Fungal_trans_2 PF11951.3 EXF77713.1 - 5.4e-79 265.5 0.0 6.9e-79 265.1 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF77713.1 - 1.7e-08 34.1 5.9 3.5e-08 33.2 4.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Epimerase PF01370.16 EXF77715.1 - 0.00049 19.5 0.0 0.00066 19.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF77715.1 - 0.0061 16.5 0.0 0.014 15.3 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EXF77715.1 - 0.067 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 KR domain NAD_binding_4 PF07993.7 EXF77715.1 - 0.092 11.6 0.0 8.9 5.1 0.0 2.2 2 0 0 2 2 2 0 Male sterility protein adh_short PF00106.20 EXF77715.1 - 0.15 11.9 0.3 0.29 11.0 0.0 1.6 2 0 0 2 2 2 0 short chain dehydrogenase PHD PF00628.24 EXF77720.1 - 7.1e-08 32.0 9.7 1.4e-07 31.0 6.7 1.5 1 0 0 1 1 1 1 PHD-finger SET PF00856.23 EXF77720.1 - 0.0014 18.9 1.1 0.0066 16.7 0.0 2.6 2 1 0 2 2 2 1 SET domain Glycos_transf_4 PF00953.16 EXF77721.1 - 1.4e-27 96.4 9.3 1.4e-27 96.4 6.5 2.1 3 0 0 3 3 3 1 Glycosyl transferase family 4 MFS_1 PF07690.11 EXF77722.1 - 1.3e-45 155.6 39.2 1.3e-45 155.6 27.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF77722.1 - 6.7e-11 41.4 27.7 3.1e-10 39.2 19.2 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter PAXIP1_C PF15364.1 EXF77722.1 - 0.045 13.6 4.1 0.074 12.9 2.8 1.2 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein OATP PF03137.15 EXF77722.1 - 0.1 10.6 4.1 4.7 5.1 2.8 2.4 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Transglut_core PF01841.14 EXF77723.1 - 7.1e-08 32.6 0.1 1.6e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.2 EXF77724.1 - 3.5e-07 29.8 0.5 6.8e-07 28.9 0.3 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EXF77724.1 - 1.8e-06 27.4 0.1 4.9e-06 26.0 0.1 1.6 1 0 0 1 1 1 1 F-box domain Spc7 PF08317.6 EXF77724.1 - 0.00039 19.1 0.9 0.00039 19.1 0.6 1.5 2 0 0 2 2 2 1 Spc7 kinetochore protein F-box-like_2 PF13013.1 EXF77724.1 - 0.0026 17.4 0.1 0.0064 16.1 0.0 1.7 1 0 0 1 1 1 1 F-box-like domain DivIC PF04977.10 EXF77724.1 - 0.35 10.3 4.7 1.5 8.3 0.2 2.7 1 1 1 2 2 2 0 Septum formation initiator Baculo_PEP_C PF04513.7 EXF77724.1 - 2 8.2 5.4 0.27 11.0 0.6 1.8 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bap31 PF05529.7 EXF77724.1 - 2.3 7.6 7.4 0.32 10.4 0.7 2.5 2 1 0 2 2 2 0 B-cell receptor-associated protein 31-like APG6 PF04111.7 EXF77724.1 - 8.7 5.2 10.9 0.29 10.1 1.8 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 Luteo_Vpg PF01659.11 EXF77725.1 - 0.00045 19.8 0.3 0.0006 19.4 0.2 1.3 1 0 0 1 1 1 1 Luteovirus putative VPg genome linked protein Cna_B PF05738.8 EXF77725.1 - 0.035 13.8 0.1 0.078 12.7 0.0 1.6 1 0 0 1 1 1 0 Cna protein B-type domain AreA_N PF07573.6 EXF77725.1 - 0.048 14.2 0.1 0.063 13.8 0.0 1.3 1 0 0 1 1 1 0 Nitrogen regulatory protein AreA N terminus TFIIB PF00382.14 EXF77726.1 - 0.00035 20.3 0.0 1.2 8.9 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat Cyclin_N PF00134.18 EXF77726.1 - 0.017 14.6 0.0 0.54 9.8 0.0 2.7 2 1 0 2 2 2 0 Cyclin, N-terminal domain DUF2737 PF10930.3 EXF77726.1 - 0.12 12.0 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2737) Vps5 PF09325.5 EXF77727.1 - 1.4e-13 50.6 1.8 2.2e-13 50.0 1.2 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EXF77727.1 - 1.2e-10 41.1 0.0 2.7e-10 40.0 0.0 1.6 1 0 0 1 1 1 1 PX domain ADH_N PF08240.7 EXF77728.1 - 1.8e-27 95.2 1.5 4e-27 94.1 1.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF77728.1 - 6.3e-18 64.5 0.9 6.2e-17 61.3 0.6 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ApbA PF02558.11 EXF77728.1 - 0.01 15.2 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EXF77728.1 - 0.012 15.2 0.3 0.019 14.6 0.2 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EXF77728.1 - 0.014 15.5 0.1 0.032 14.3 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 EXF77728.1 - 0.018 14.4 0.2 0.039 13.3 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.13 EXF77728.1 - 0.019 14.9 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Pyr_redox PF00070.22 EXF77728.1 - 0.033 14.5 0.4 0.18 12.2 0.3 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF77728.1 - 0.043 13.8 0.9 0.12 12.3 0.4 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ThiF PF00899.16 EXF77728.1 - 0.044 13.5 0.7 0.091 12.5 0.5 1.4 1 0 0 1 1 1 0 ThiF family Pyr_redox_3 PF13738.1 EXF77728.1 - 0.1 12.6 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AdoHcyase_NAD PF00670.16 EXF77728.1 - 0.11 12.3 0.4 0.21 11.4 0.3 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Methyltransf_18 PF12847.2 EXF77728.1 - 0.15 12.6 0.1 0.32 11.6 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain NADH_4Fe-4S PF10589.4 EXF77728.1 - 0.2 10.8 4.5 0.42 9.8 3.1 1.5 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region JAB PF01398.16 EXF77729.1 - 8.8e-07 28.6 0.0 2.7e-06 27.0 0.0 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EXF77729.1 - 1.6e-05 24.9 0.0 0.0033 17.4 0.0 2.7 2 1 0 2 2 2 2 Maintenance of mitochondrial structure and function Phage_GPL PF05926.6 EXF77731.1 - 0.09 12.6 0.1 0.099 12.4 0.1 1.1 1 0 0 1 1 1 0 Phage head completion protein (GPL) MFS_1 PF07690.11 EXF77732.1 - 9.7e-05 21.2 26.5 9.7e-05 21.2 18.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EXF77732.1 - 0.00025 20.5 3.1 0.00025 20.5 2.1 3.1 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 ABC2_membrane_4 PF12730.2 EXF77732.1 - 6.5 5.8 17.2 0.37 9.9 5.7 2.8 2 1 1 3 3 3 0 ABC-2 family transporter protein DUF3024 PF11225.3 EXF77733.1 - 0.41 10.5 0.1 0.41 10.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3024) RVT_1 PF00078.22 EXF77734.1 - 1.2e-21 77.0 0.0 2.3e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) BCIP PF13862.1 EXF77735.1 - 9.5e-66 221.0 0.1 1.2e-65 220.6 0.1 1.1 1 0 0 1 1 1 1 p21-C-terminal region-binding protein DNA_pol3_chi PF04364.8 EXF77735.1 - 0.077 12.8 0.2 0.13 12.0 0.1 1.4 1 0 0 1 1 1 0 DNA polymerase III chi subunit, HolC CM_2 PF01817.16 EXF77736.1 - 9.8e-09 35.1 0.2 2.3e-06 27.6 0.0 2.9 2 1 0 2 2 2 2 Chorismate mutase type II WD40 PF00400.27 EXF77737.1 - 7.9e-40 133.3 6.3 3.3e-10 39.4 0.2 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EXF77737.1 - 3.8e-05 22.0 9.0 0.024 12.7 0.3 4.2 2 2 3 5 5 5 2 Nucleoporin Nup120/160 APG6 PF04111.7 EXF77737.1 - 0.074 12.0 1.8 0.13 11.3 1.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EXF77737.1 - 0.22 11.0 2.6 0.44 10.1 1.7 1.5 1 1 0 1 1 1 0 IncA protein CENP-Q PF13094.1 EXF77738.1 - 0.0034 17.4 1.4 0.0034 17.4 1.0 3.2 3 0 0 3 3 3 1 CENP-Q, a CENPA-CAD centromere complex subunit BLOC1_2 PF10046.4 EXF77738.1 - 0.062 13.4 6.5 0.079 13.0 0.8 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.16 EXF77738.1 - 0.19 11.7 15.2 1.8 8.6 4.6 3.0 2 1 0 2 2 2 0 bZIP transcription factor Herpes_UL6 PF01763.11 EXF77738.1 - 0.44 8.6 5.0 0.37 8.9 1.4 2.0 1 1 0 2 2 2 0 Herpesvirus UL6 like DUF4200 PF13863.1 EXF77738.1 - 0.6 10.0 11.4 1.1 9.1 4.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF904 PF06005.7 EXF77738.1 - 1.6 9.0 11.3 0.56 10.5 2.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF972 PF06156.8 EXF77738.1 - 2.5 8.4 14.7 2 8.7 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Rootletin PF15035.1 EXF77738.1 - 6.8 6.6 18.6 0.13 12.2 3.1 3.1 3 0 0 3 3 3 0 Ciliary rootlet component, centrosome cohesion Prefoldin_2 PF01920.15 EXF77738.1 - 8.8 6.1 13.1 15 5.4 3.6 2.6 2 0 0 2 2 2 0 Prefoldin subunit GRAM PF02893.15 EXF77739.1 - 2.6e-17 62.0 0.0 4.7e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 GRAM domain Dynamin_N PF00350.18 EXF77740.1 - 3.6e-31 108.2 0.4 8.8e-31 106.9 0.1 1.8 2 0 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 EXF77740.1 - 9.8e-17 60.6 0.7 8.8e-16 57.5 0.0 2.1 2 0 0 2 2 2 1 Dynamin central region GED PF02212.13 EXF77740.1 - 0.00032 20.5 1.3 0.00066 19.5 0.1 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EXF77740.1 - 0.001 18.9 0.4 0.01 15.7 0.2 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EXF77740.1 - 0.0036 17.8 0.1 0.014 15.8 0.0 2.1 2 0 0 2 2 2 1 Miro-like protein PPP4R2 PF09184.6 EXF77740.1 - 0.021 14.3 1.2 0.11 12.0 0.0 2.2 2 0 0 2 2 2 0 PPP4R2 AIG1 PF04548.11 EXF77740.1 - 0.061 12.4 0.1 2.4 7.2 0.1 2.5 2 0 0 2 2 2 0 AIG1 family GCFC PF07842.7 EXF77740.1 - 0.076 12.3 0.1 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein FeoB_N PF02421.13 EXF77740.1 - 0.078 12.2 0.2 5.8 6.1 0.1 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B MFS_1 PF07690.11 EXF77741.1 - 2e-34 118.8 28.8 2e-34 118.8 19.9 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF77741.1 - 7.3e-16 57.7 19.7 9.7e-16 57.3 13.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF1772 PF08592.6 EXF77741.1 - 0.085 12.5 10.3 2.1 8.0 0.2 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF1772) adh_short PF00106.20 EXF77742.1 - 5.3e-28 98.0 1.1 6.6e-28 97.7 0.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF77742.1 - 4e-21 75.9 0.0 5.3e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF77742.1 - 1.2e-10 41.3 0.0 1.7e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EXF77742.1 - 0.013 14.4 0.0 0.016 14.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EXF77742.1 - 0.038 13.9 0.3 0.061 13.3 0.2 1.5 1 1 0 1 1 1 0 NADH(P)-binding Choline_kin_N PF04428.9 EXF77742.1 - 0.14 11.6 0.0 1.1 8.7 0.0 2.2 1 1 0 1 1 1 0 Choline kinase N terminus p450 PF00067.17 EXF77743.1 - 8.3e-37 126.7 0.0 1.3e-36 126.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Rhodanese PF00581.15 EXF77744.1 - 9.4e-07 29.1 0.0 2.3e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Homeobox PF00046.24 EXF77744.1 - 2.6e-05 23.7 0.2 5.7e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 Homeobox domain Peptidase_C14 PF00656.17 EXF77744.1 - 0.0044 16.7 0.0 0.035 13.7 0.0 1.9 1 1 1 2 2 2 1 Caspase domain PIG-X PF08320.7 EXF77745.1 - 7.2e-66 221.4 0.0 1.1e-65 220.8 0.0 1.3 1 0 0 1 1 1 1 PIG-X / PBN1 2OG-FeII_Oxy_3 PF13640.1 EXF77746.1 - 0.0026 18.2 0.3 0.03 14.8 0.2 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 EXF77747.1 - 3.9e-05 22.6 0.1 8.5e-05 21.5 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain T2SF PF00482.18 EXF77747.1 - 0.15 11.9 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F AAA_18 PF13238.1 EXF77748.1 - 1.3e-10 41.6 0.0 2.7e-10 40.6 0.0 1.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 EXF77748.1 - 1.8e-06 27.8 0.0 2.5e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EXF77748.1 - 6.5e-05 23.7 0.0 0.00031 21.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EXF77748.1 - 0.00075 19.1 0.0 0.0011 18.5 0.0 1.5 1 1 0 1 1 1 1 Adenylylsulphate kinase AAA_16 PF13191.1 EXF77748.1 - 0.013 15.4 0.0 0.024 14.6 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 EXF77748.1 - 0.023 14.4 0.0 0.64 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SKI PF01202.17 EXF77748.1 - 0.066 13.0 0.0 5.2 6.9 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase MMR_HSR1 PF01926.18 EXF77748.1 - 0.15 12.0 0.1 0.33 10.9 0.1 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase PBP PF01161.15 EXF77749.1 - 4.4e-20 72.0 0.0 6.1e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PrpF PF04303.8 EXF77750.1 - 2.1e-86 289.9 0.0 2.7e-86 289.6 0.0 1.1 1 0 0 1 1 1 1 PrpF protein EF-1_beta_acid PF10587.4 EXF77751.1 - 0.73 10.0 2.1 1.4 9.1 1.5 1.4 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region GMC_oxred_N PF00732.14 EXF77752.1 - 2.3e-57 194.4 0.0 3.1e-57 193.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF77752.1 - 2.9e-38 131.4 0.0 5.1e-38 130.5 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EXF77752.1 - 1.4e-05 24.2 0.1 0.038 12.8 0.0 2.5 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF77752.1 - 0.00046 20.1 0.0 0.0014 18.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EXF77752.1 - 0.0092 14.9 0.7 0.016 14.1 0.2 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EXF77752.1 - 0.015 15.1 0.8 0.19 11.5 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AIG2_2 PF13772.1 EXF77753.1 - 7e-08 32.4 0.0 2.2e-07 30.8 0.0 1.9 2 1 0 2 2 2 1 AIG2-like family AIG2 PF06094.7 EXF77753.1 - 6.7e-05 23.3 0.0 0.00015 22.2 0.0 1.6 1 1 0 1 1 1 1 AIG2-like family LacAB_rpiB PF02502.13 EXF77754.1 - 5.1e-44 149.3 0.2 5.8e-44 149.1 0.1 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase TPIP1 PF15338.1 EXF77754.1 - 0.098 12.5 0.1 0.18 11.6 0.1 1.5 1 1 0 1 1 1 0 p53-regulated apoptosis-inducing protein 1 F_bP_aldolase PF01116.15 EXF77755.1 - 4.7e-81 272.0 0.7 5.3e-81 271.8 0.5 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II PTE PF02126.13 EXF77755.1 - 0.054 12.4 0.1 0.091 11.7 0.1 1.3 1 0 0 1 1 1 0 Phosphotriesterase family DUF3588 PF12140.3 EXF77755.1 - 0.082 12.9 0.0 0.41 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3588) Fungal_trans_2 PF11951.3 EXF77756.1 - 1.9e-10 39.9 0.0 3.9e-10 38.8 0.0 1.5 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF77756.1 - 4e-07 29.8 7.3 8e-07 28.8 5.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dak1 PF02733.12 EXF77757.1 - 3.4e-112 374.2 0.1 5.8e-112 373.4 0.0 1.3 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EXF77757.1 - 3.4e-35 121.2 0.3 5.7e-35 120.5 0.2 1.4 1 0 0 1 1 1 1 DAK2 domain Zip PF02535.17 EXF77760.1 - 7.6 5.4 9.7 10 5.0 6.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Sugar_tr PF00083.19 EXF77761.1 - 3.7e-46 157.6 13.1 5.5e-46 157.0 9.1 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF77761.1 - 2.6e-23 82.3 22.7 5.3e-23 81.3 15.6 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_1 PF00561.15 EXF77762.1 - 2.3e-43 148.3 0.0 4.8e-43 147.3 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EXF77762.1 - 2.5e-12 47.1 0.9 6e-11 42.6 0.6 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EXF77762.1 - 0.1 12.4 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein Tho2 PF11262.3 EXF77763.1 - 9.7e-79 264.5 0.0 1.7e-78 263.7 0.0 1.4 1 0 0 1 1 1 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EXF77763.1 - 9.7e-26 89.3 0.1 1.9e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Transcription- and export-related complex subunit DUF4289 PF14121.1 EXF77763.1 - 2.1 6.6 0.0 3.1 6.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4289) Glyco_transf_34 PF05637.7 EXF77765.1 - 1.9e-19 70.1 0.0 3e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family MBOAT_2 PF13813.1 EXF77766.1 - 0.0018 18.2 0.4 0.0071 16.4 0.3 2.0 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Pox_A14 PF05767.7 EXF77766.1 - 0.032 14.1 0.3 0.032 14.1 0.2 3.0 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 DUF2975 PF11188.3 EXF77766.1 - 0.17 11.6 0.1 0.17 11.6 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) Zn_clus PF00172.13 EXF77767.1 - 0.0066 16.3 8.7 0.014 15.3 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF221 PF02714.10 EXF77768.1 - 4.1e-103 344.6 29.1 4.1e-103 344.6 20.2 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EXF77768.1 - 1.7e-43 147.8 1.2 1.7e-43 147.8 0.8 3.1 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EXF77768.1 - 4.1e-29 100.3 0.2 2.2e-28 97.9 0.0 2.2 2 0 0 2 2 2 1 Phosphate metabolism protein DUF4463 PF14703.1 EXF77768.1 - 3.2e-23 82.0 0.3 4.9e-23 81.4 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) YvbH_ext PF11724.3 EXF77769.1 - 0.037 13.7 1.0 0.092 12.4 0.7 1.6 1 0 0 1 1 1 0 YvbH-like oligomerisation region SKG6 PF08693.5 EXF77770.1 - 0.094 12.0 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Solute_trans_a PF03619.11 EXF77771.1 - 3.6e-78 262.6 20.2 4.3e-78 262.4 14.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha WSC PF01822.14 EXF77772.1 - 3e-12 46.2 9.5 3e-12 46.2 6.6 2.1 2 1 0 2 2 2 1 WSC domain Podoplanin PF05808.6 EXF77772.1 - 0.0047 16.5 10.1 0.0085 15.6 7.0 1.3 1 0 0 1 1 1 1 Podoplanin IncA PF04156.9 EXF77772.1 - 0.01 15.4 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 IncA protein SKG6 PF08693.5 EXF77772.1 - 0.015 14.5 7.7 0.067 12.5 5.3 2.1 1 1 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 EXF77772.1 - 0.024 14.1 0.0 0.055 13.0 0.0 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Gram_pos_anchor PF00746.16 EXF77772.1 - 0.035 13.8 1.2 0.085 12.6 0.8 1.7 1 0 0 1 1 1 0 Gram positive anchor DUF4366 PF14283.1 EXF77772.1 - 0.047 13.1 5.2 1.5 8.1 3.6 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4118 PF13493.1 EXF77772.1 - 0.059 13.5 0.0 3.5 7.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4118) EphA2_TM PF14575.1 EXF77772.1 - 0.073 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ctr PF04145.10 EXF77772.1 - 0.15 12.1 0.1 1.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Ctr copper transporter family PI-PLC-X PF00388.14 EXF77773.1 - 8.5e-12 44.6 0.0 1.2e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Dynamin_N PF00350.18 EXF77774.1 - 5.9e-09 35.9 0.0 9.9e-08 31.9 0.0 2.3 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EXF77774.1 - 1.5e-05 24.8 0.0 0.0059 16.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase DUF258 PF03193.11 EXF77774.1 - 6.1e-05 22.2 0.0 0.00029 20.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EXF77774.1 - 0.00088 19.3 1.4 0.0023 17.9 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.22 EXF77774.1 - 0.0031 17.8 0.0 0.029 14.6 0.0 2.4 2 0 0 2 2 2 1 ABC transporter AAA_22 PF13401.1 EXF77774.1 - 0.057 13.5 0.0 0.24 11.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EXF77774.1 - 0.18 12.2 0.0 0.7 10.4 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein Pectate_lyase PF03211.8 EXF77775.1 - 1.9e-77 259.5 9.9 2.3e-77 259.2 6.9 1.0 1 0 0 1 1 1 1 Pectate lyase TPR_2 PF07719.12 EXF77776.1 - 6.4e-14 50.6 11.7 0.00021 20.9 0.0 6.2 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 EXF77776.1 - 7.4e-13 47.9 8.0 5.2e-06 26.0 0.0 4.9 5 1 1 6 6 6 3 TPR repeat TPR_16 PF13432.1 EXF77776.1 - 9.9e-11 42.0 15.1 0.00015 22.3 0.4 6.1 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.23 EXF77776.1 - 1.6e-10 40.1 8.2 0.0019 17.7 0.0 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.1 EXF77776.1 - 3.4e-09 36.5 6.6 0.0044 16.9 0.1 5.2 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EXF77776.1 - 4.3e-08 32.3 0.2 0.14 12.0 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EXF77776.1 - 6.8e-07 29.0 0.9 9.8 6.6 0.0 6.1 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.1 EXF77776.1 - 1.1e-06 28.8 2.9 0.0051 17.1 0.0 4.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_4 PF07721.9 EXF77776.1 - 0.0038 17.5 13.7 0.12 12.9 1.1 4.6 6 0 0 6 6 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EXF77776.1 - 0.0046 16.6 0.7 9.2 6.3 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EXF77776.1 - 0.014 15.7 4.3 42 4.9 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EXF77776.1 - 0.018 14.9 2.4 26 4.9 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EXF77776.1 - 0.023 15.3 16.3 5.4 7.9 0.6 6.9 5 2 2 7 7 7 0 Tetratricopeptide repeat AA_permease_2 PF13520.1 EXF77777.1 - 7.1e-51 173.0 49.1 9e-51 172.7 34.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF77777.1 - 3.5e-24 84.9 44.6 4.9e-24 84.5 30.9 1.1 1 0 0 1 1 1 1 Amino acid permease p450 PF00067.17 EXF77778.1 - 3.2e-38 131.4 0.0 4e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S9 PF00326.16 EXF77779.1 - 2.4e-48 164.1 0.9 4.2e-48 163.3 0.6 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DPPIV_N PF00930.16 EXF77779.1 - 6.6e-41 140.0 0.0 1.5e-40 138.9 0.0 1.6 1 1 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Abhydrolase_5 PF12695.2 EXF77779.1 - 7.4e-09 35.5 0.1 1.6e-08 34.4 0.1 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EXF77779.1 - 4.1e-07 29.6 1.2 2.4e-06 27.1 0.8 1.9 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 EXF77779.1 - 5.7e-05 22.5 0.0 0.00013 21.3 0.0 1.5 1 1 0 1 1 1 1 Dienelactone hydrolase family VHL PF01847.11 EXF77779.1 - 0.00021 20.8 0.0 0.00044 19.8 0.0 1.4 1 0 0 1 1 1 1 von Hippel-Lindau disease tumour suppressor protein Transglut_C PF00927.17 EXF77779.1 - 0.078 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase family, C-terminal ig like domain Abhydrolase_3 PF07859.8 EXF77779.1 - 0.31 10.5 2.5 11 5.5 1.8 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold Fungal_trans_2 PF11951.3 EXF77780.1 - 4.2e-25 88.1 0.7 1.8e-12 46.5 0.3 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF77780.1 - 8e-08 32.0 14.2 1.8e-07 30.9 9.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PhyH PF05721.8 EXF77781.1 - 1.4e-24 87.2 0.0 2e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MFS_1 PF07690.11 EXF77782.1 - 8.4e-35 120.1 40.4 8.4e-35 120.1 28.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily LSM PF01423.17 EXF77783.1 - 1.4e-15 56.5 0.0 3.5e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 LSM domain PPR_2 PF13041.1 EXF77783.1 - 0.00054 19.8 0.0 6.2 6.8 0.0 4.6 5 1 1 6 6 6 1 PPR repeat family PPR_3 PF13812.1 EXF77783.1 - 0.0011 19.0 2.3 11 6.6 0.0 6.8 8 0 0 8 8 8 1 Pentatricopeptide repeat domain PPR PF01535.15 EXF77783.1 - 0.19 11.7 3.7 9.3 6.4 0.0 4.5 6 0 0 6 6 6 0 PPR repeat Sulfatase PF00884.18 EXF77784.1 - 5.6e-61 206.3 0.8 5.6e-61 206.3 0.5 1.4 2 0 0 2 2 2 1 Sulfatase Phosphodiest PF01663.17 EXF77784.1 - 8e-06 25.4 3.1 7.7e-05 22.1 2.2 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EXF77784.1 - 0.0024 16.3 0.0 0.0039 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF229) DUF1501 PF07394.7 EXF77784.1 - 0.031 13.1 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) MFS_1 PF07690.11 EXF77785.1 - 1.5e-37 129.1 32.5 1.5e-37 129.1 22.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF77785.1 - 4.8e-12 45.1 27.5 6.9e-12 44.6 19.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EXF77785.1 - 1.7e-08 33.1 5.9 2.6e-08 32.5 4.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_3 PF05977.8 EXF77785.1 - 0.0047 15.1 2.2 0.0074 14.4 1.5 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector TgMIC1 PF11476.3 EXF77786.1 - 0.022 14.3 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 Toxoplasma gondii micronemal protein 1 TgMIC1 Peptidase_M28 PF04389.12 EXF77787.1 - 0.062 13.0 0.0 0.083 12.6 0.0 1.5 1 1 0 1 1 1 0 Peptidase family M28 Peptidase_M20 PF01546.23 EXF77787.1 - 0.079 12.4 0.0 0.079 12.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 ketoacyl-synt PF00109.21 EXF77788.1 - 5.1e-70 235.8 0.1 1.2e-69 234.5 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EXF77788.1 - 7.8e-65 219.2 0.0 1.2e-64 218.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EXF77788.1 - 1.2e-54 184.7 0.2 3.2e-54 183.3 0.1 1.8 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 EXF77788.1 - 1.4e-52 178.7 0.0 2.4e-52 177.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EXF77788.1 - 1.9e-42 145.0 0.2 4.1e-42 143.9 0.2 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EXF77788.1 - 1.7e-30 105.3 0.0 3.7e-30 104.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EXF77788.1 - 4e-11 42.5 0.0 1.8e-10 40.4 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 EXF77788.1 - 0.0057 15.6 0.1 0.01 14.8 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_31 PF13847.1 EXF77788.1 - 0.022 14.3 0.0 0.06 12.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EXF77788.1 - 0.039 14.4 0.0 0.33 11.4 0.0 2.6 3 0 0 3 3 3 0 Methyltransferase domain AMP-binding PF00501.23 EXF77789.1 - 8.7e-91 304.3 0.0 1.1e-90 304.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EXF77789.1 - 1.9e-18 67.1 0.4 3e-17 63.3 0.0 2.3 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain p450 PF00067.17 EXF77790.1 - 2.3e-43 148.4 0.0 3.7e-42 144.4 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EXF77791.1 - 1.9e-30 105.6 0.1 2.8e-30 105.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EXF77792.1 - 1e-43 149.4 50.8 9.5e-43 146.2 35.2 2.2 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1 PF07690.11 EXF77793.1 - 1.1e-21 76.9 19.4 2.7e-21 75.6 13.3 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Dioxygenase_C PF00775.16 EXF77794.1 - 8.2e-10 38.2 0.1 6.2e-07 28.8 0.0 2.5 2 1 0 2 2 2 2 Dioxygenase Lipoxygenase PF00305.14 EXF77795.1 - 1.9e-35 122.0 0.0 3.2e-35 121.3 0.0 1.2 1 0 0 1 1 1 1 Lipoxygenase Amidohydro_1 PF01979.15 EXF77796.1 - 1.7e-42 146.2 0.0 2.2e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EXF77796.1 - 4.5e-06 26.3 0.0 1.7e-05 24.5 0.0 2.0 1 1 1 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EXF77796.1 - 1.7e-05 24.2 3.1 0.0011 18.2 0.0 2.9 2 1 0 3 3 3 2 Amidohydrolase family Amidohydro_4 PF13147.1 EXF77796.1 - 0.00097 19.2 0.7 0.019 15.0 0.0 2.8 2 1 0 2 2 2 1 Amidohydrolase DUF2802 PF10975.3 EXF77796.1 - 0.061 13.0 0.1 0.35 10.6 0.1 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2802) Acyl_transf_1 PF00698.16 EXF77797.1 - 1.2e-79 267.9 0.0 3.5e-78 263.1 0.0 2.9 3 0 0 3 3 3 1 Acyl transferase domain MaoC_dehydratas PF01575.14 EXF77797.1 - 7.3e-39 131.9 0.0 1.6e-38 130.8 0.0 1.6 1 0 0 1 1 1 1 MaoC like domain DUF1729 PF08354.5 EXF77797.1 - 2.8e-28 97.4 0.4 7.3e-28 96.1 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1729) MaoC_dehydrat_N PF13452.1 EXF77797.1 - 2.9e-22 78.8 0.6 1.4e-21 76.6 0.0 2.6 3 0 0 3 3 3 1 N-terminal half of MaoC dehydratase NMO PF03060.10 EXF77797.1 - 9.6e-07 28.2 0.2 9.8e-06 24.9 0.2 2.2 1 1 0 1 1 1 1 Nitronate monooxygenase TPR_12 PF13424.1 EXF77797.1 - 0.043 13.7 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat PCIF1_WW PF12237.3 EXF77797.1 - 0.18 11.1 0.0 1 8.5 0.0 2.0 2 0 0 2 2 2 0 Phosphorylated CTD interacting factor 1 WW domain ketoacyl-synt PF00109.21 EXF77798.1 - 4.8e-19 68.8 0.1 9.9e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain adh_short_C2 PF13561.1 EXF77798.1 - 1.4e-18 67.5 0.0 4.3e-18 65.9 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase ACPS PF01648.15 EXF77798.1 - 1.1e-17 63.8 0.1 2.6e-17 62.6 0.0 1.7 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Ketoacyl-synt_C PF02801.17 EXF77798.1 - 4.5e-11 42.6 0.1 1.4e-10 41.0 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EXF77798.1 - 4.1e-05 23.5 0.0 0.00012 21.9 0.0 1.9 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF77798.1 - 0.017 14.8 0.0 0.049 13.2 0.0 1.8 1 0 0 1 1 1 0 KR domain Macoilin PF09726.4 EXF77799.1 - 0.032 12.5 16.3 0.049 11.9 11.3 1.2 1 0 0 1 1 1 0 Transmembrane protein Spatacsin_C PF14649.1 EXF77799.1 - 0.5 9.1 6.2 1.3 7.7 4.3 1.7 1 1 0 1 1 1 0 Spatacsin C-terminus DUF2559 PF10832.3 EXF77799.1 - 4.2 7.2 9.2 0.31 10.8 0.2 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2559) Cyt-b5 PF00173.23 EXF77800.1 - 4.6e-09 35.9 0.0 6.9e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Cupredoxin_1 PF13473.1 EXF77801.1 - 0.046 13.6 0.2 0.22 11.4 0.1 1.9 1 1 1 2 2 2 0 Cupredoxin-like domain FinO_N PF12602.3 EXF77801.1 - 0.082 13.2 0.1 0.2 11.9 0.1 1.6 1 1 0 1 1 1 0 Fertility inhibition protein N terminal DUF2263 PF10021.4 EXF77801.1 - 0.12 12.4 3.1 0.08 12.9 0.8 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2263) Cu_bind_like PF02298.12 EXF77801.1 - 0.16 11.7 0.3 0.79 9.5 0.2 2.0 1 1 0 1 1 1 0 Plastocyanin-like domain CENP-X PF09415.5 EXF77802.1 - 1.1e-23 82.7 0.0 1.1e-23 82.7 0.0 1.6 2 0 0 2 2 2 1 CENP-S associating Centromere protein X Herpes_TAF50 PF03326.8 EXF77802.1 - 0.09 11.7 1.4 0.094 11.6 1.0 1.0 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Nucleoplasmin PF03066.10 EXF77802.1 - 0.17 11.4 6.2 0.23 10.9 4.3 1.1 1 0 0 1 1 1 0 Nucleoplasmin NOA36 PF06524.7 EXF77802.1 - 0.6 9.3 2.5 0.77 8.9 1.7 1.1 1 0 0 1 1 1 0 NOA36 protein Sigma70_ner PF04546.8 EXF77802.1 - 0.95 9.0 6.4 1.2 8.7 4.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Daxx PF03344.10 EXF77802.1 - 1 7.7 9.2 1.2 7.5 6.4 1.0 1 0 0 1 1 1 0 Daxx Family CENP-B_dimeris PF09026.5 EXF77802.1 - 3.1 8.0 9.0 5 7.4 6.2 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Mito_carr PF00153.22 EXF77803.1 - 6.3e-64 211.7 3.6 1.1e-21 76.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Bromodomain PF00439.20 EXF77804.1 - 4.8e-09 36.0 0.0 1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Bromodomain adh_short PF00106.20 EXF77805.1 - 6.8e-15 55.3 5.7 1.2e-13 51.3 3.9 2.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF77805.1 - 1e-07 31.7 0.3 2.1e-07 30.8 0.0 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.7 EXF77805.1 - 0.0024 16.8 0.0 0.0075 15.2 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein E1-E2_ATPase PF00122.15 EXF77806.1 - 4e-57 192.8 0.2 4e-57 192.8 0.2 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EXF77806.1 - 1.1e-43 148.8 9.4 1.1e-43 148.8 6.5 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EXF77806.1 - 1.5e-29 103.9 0.0 1.6e-28 100.6 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EXF77806.1 - 2.1e-18 66.0 0.0 5.8e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EXF77806.1 - 2.9e-15 56.9 0.0 6.3e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EXF77806.1 - 1e-05 24.8 0.0 3.3e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EXF77806.1 - 0.00096 18.7 0.3 0.0018 17.9 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Tautomerase_3 PF14832.1 EXF77807.1 - 9.6e-12 45.0 0.0 1.4e-11 44.5 0.0 1.4 1 1 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.16 EXF77807.1 - 0.0018 17.8 0.0 0.0032 17.0 0.0 1.4 1 0 0 1 1 1 1 Tautomerase enzyme DASH_Spc34 PF08657.5 EXF77807.1 - 0.057 13.0 0.1 0.22 11.1 0.1 1.7 2 0 0 2 2 2 0 DASH complex subunit Spc34 adh_short PF00106.20 EXF77808.1 - 2.4e-29 102.3 0.0 3.1e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF77808.1 - 2.4e-17 63.5 0.0 3.6e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF77808.1 - 2e-12 47.1 0.0 3.9e-12 46.2 0.0 1.4 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF77808.1 - 1.1e-05 24.9 0.1 1.8e-05 24.3 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF77808.1 - 3.5e-05 23.9 0.2 9e-05 22.5 0.1 1.8 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EXF77808.1 - 0.0024 16.8 0.0 0.0026 16.6 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Chorion_1 PF01723.11 EXF77808.1 - 0.011 15.5 0.6 0.02 14.8 0.4 1.4 1 0 0 1 1 1 0 Chorion protein Eno-Rase_NADH_b PF12242.3 EXF77808.1 - 0.11 12.3 0.2 0.23 11.2 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase HSP70 PF00012.15 EXF77809.1 - 1.7e-58 198.0 10.3 1.3e-55 188.5 0.2 3.3 2 1 2 4 4 4 3 Hsp70 protein Mucin PF01456.12 EXF77809.1 - 1.9 8.2 22.8 1.5 8.5 5.9 3.2 3 0 0 3 3 3 0 Mucin-like glycoprotein Asp PF00026.18 EXF77810.1 - 2.6e-29 102.4 0.0 3.5e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EXF77810.1 - 0.00074 19.5 0.0 0.013 15.4 0.0 2.6 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal DASH_Spc34 PF08657.5 EXF77811.1 - 0.0038 16.9 0.7 0.0047 16.6 0.5 1.3 1 0 0 1 1 1 1 DASH complex subunit Spc34 DivIVA PF05103.8 EXF77811.1 - 0.0051 16.8 2.1 0.0072 16.3 1.5 1.1 1 0 0 1 1 1 1 DivIVA protein DUF4200 PF13863.1 EXF77811.1 - 0.0091 15.9 3.0 0.013 15.4 2.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) Tropomyosin PF00261.15 EXF77811.1 - 0.016 14.3 4.2 0.019 14.0 2.9 1.2 1 0 0 1 1 1 0 Tropomyosin Dynamitin PF04912.9 EXF77811.1 - 0.018 13.8 0.1 0.018 13.8 0.1 1.1 1 0 0 1 1 1 0 Dynamitin Tropomyosin_1 PF12718.2 EXF77811.1 - 0.024 14.5 3.5 0.033 14.0 2.5 1.2 1 0 0 1 1 1 0 Tropomyosin like SGT1 PF07093.6 EXF77811.1 - 0.029 12.7 2.9 0.029 12.7 2.0 1.0 1 0 0 1 1 1 0 SGT1 protein Viral_P18 PF04521.8 EXF77811.1 - 0.064 12.7 1.1 0.093 12.1 0.7 1.2 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein DUF2514 PF10721.4 EXF77811.1 - 0.11 12.2 6.7 0.13 11.9 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) EAP30 PF04157.11 EXF77811.1 - 0.21 10.7 2.9 0.27 10.3 2.0 1.2 1 0 0 1 1 1 0 EAP30/Vps36 family FliD_N PF02465.13 EXF77811.1 - 0.24 11.8 2.3 0.34 11.3 1.6 1.3 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus IncA PF04156.9 EXF77811.1 - 0.24 10.9 2.4 0.34 10.5 1.6 1.2 1 0 0 1 1 1 0 IncA protein Mnd1 PF03962.10 EXF77811.1 - 0.35 10.5 3.0 0.42 10.2 2.1 1.1 1 0 0 1 1 1 0 Mnd1 family DivIC PF04977.10 EXF77811.1 - 1.1 8.7 4.8 2.4 7.7 3.3 1.5 1 0 0 1 1 1 0 Septum formation initiator APC_CDC26 PF10471.4 EXF77811.1 - 3.4 8.4 8.5 37 5.1 5.9 2.3 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 SlyX PF04102.7 EXF77811.1 - 5.2 7.5 9.4 0.24 11.7 2.1 1.9 2 0 0 2 2 2 0 SlyX Ribosomal_S25 PF03297.10 EXF77812.1 - 2.5e-31 107.8 2.6 4e-31 107.1 1.3 1.6 1 1 1 2 2 2 1 S25 ribosomal protein HTH_24 PF13412.1 EXF77812.1 - 0.012 15.0 0.1 0.026 13.9 0.1 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding MarR_2 PF12802.2 EXF77812.1 - 0.1 12.2 0.1 0.24 11.0 0.0 1.6 2 0 0 2 2 2 0 MarR family HTH_DeoR PF08220.7 EXF77812.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 DeoR-like helix-turn-helix domain Ribosomal_S7 PF00177.16 EXF77813.1 - 8.7e-41 138.9 1.3 1.1e-40 138.6 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e Acetyltransf_1 PF00583.19 EXF77814.1 - 5.5e-06 26.3 1.0 8.8e-05 22.4 0.7 2.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.1 EXF77814.1 - 0.00047 20.6 0.0 0.42 11.1 0.0 2.9 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EXF77814.1 - 0.0033 17.5 0.0 0.01 15.9 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain HMA PF00403.21 EXF77815.1 - 2e-15 56.6 0.4 2e-15 56.6 0.3 1.3 2 0 0 2 2 2 1 Heavy-metal-associated domain Tcf25 PF04910.9 EXF77816.1 - 1.4e-70 238.0 0.0 2.8e-70 237.0 0.0 1.5 1 0 0 1 1 1 1 Transcriptional repressor TCF25 DUF2422 PF10337.4 EXF77816.1 - 1 8.0 3.9 1.8 7.2 2.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) RNA_polI_A34 PF08208.6 EXF77816.1 - 1.9 8.1 16.2 3.5 7.2 11.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 LSM14 PF12701.2 EXF77817.1 - 1.2e-34 118.0 0.0 1.9e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.5 EXF77817.1 - 8.6e-22 77.6 0.6 1.7e-21 76.7 0.4 1.5 1 0 0 1 1 1 1 FDF domain SM-ATX PF14438.1 EXF77817.1 - 4.1e-06 26.6 0.0 7e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain Steroid_dh PF02544.11 EXF77819.1 - 9.5e-33 113.0 0.6 1.3e-32 112.6 0.4 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EXF77819.1 - 8.4e-05 21.9 1.4 0.00027 20.3 0.4 1.9 1 1 1 2 2 2 1 Protein of unknown function (DUF1295) PEMT PF04191.8 EXF77819.1 - 0.0076 16.3 0.2 0.035 14.2 0.1 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase Flavi_NS4B PF01349.12 EXF77819.1 - 0.016 14.1 0.0 2 7.2 0.0 2.3 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4B ubiquitin PF00240.18 EXF77819.1 - 0.082 12.3 0.1 0.39 10.1 0.0 2.0 2 0 0 2 2 2 0 Ubiquitin family GCN5L1 PF06320.8 EXF77820.1 - 1.4e-07 31.3 0.2 1.4e-07 31.3 0.1 1.8 2 0 0 2 2 2 1 GCN5-like protein 1 (GCN5L1) eIF3_N PF09440.5 EXF77820.1 - 0.028 14.5 0.2 0.064 13.4 0.1 1.5 1 0 0 1 1 1 0 eIF3 subunit 6 N terminal domain Macoilin PF09726.4 EXF77820.1 - 0.56 8.4 9.8 0.011 14.1 1.3 1.8 2 0 0 2 2 2 0 Transmembrane protein IncA PF04156.9 EXF77820.1 - 1.1 8.8 6.0 0.15 11.6 0.3 2.0 2 0 0 2 2 2 0 IncA protein HAUS6_N PF14661.1 EXF77820.1 - 4.8 6.4 7.5 0.22 10.8 0.9 1.8 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF1993 PF09351.5 EXF77821.1 - 8.6e-39 133.0 0.2 1.5e-37 128.9 0.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1993) DinB PF05163.7 EXF77821.1 - 0.054 13.2 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 DinB family SOG2 PF10428.4 EXF77822.1 - 7.1e-95 318.2 0.4 1.5e-94 317.1 0.0 1.8 2 0 0 2 2 2 1 RAM signalling pathway protein LRR_4 PF12799.2 EXF77822.1 - 4.1e-17 61.3 4.0 2.9e-07 29.9 0.2 4.2 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EXF77822.1 - 4.3e-16 58.3 0.8 1.3e-09 37.6 0.0 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EXF77822.1 - 6.2e-10 37.7 3.4 0.43 10.8 0.0 6.4 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EXF77822.1 - 7.1e-07 28.4 0.2 2.7 8.5 0.0 5.7 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 EXF77822.1 - 0.00031 20.5 0.9 4.4 7.6 0.0 4.5 4 0 0 4 4 4 2 Leucine Rich repeat Helicase_C PF00271.26 EXF77823.1 - 7.8e-20 70.5 0.0 1e-16 60.5 0.0 2.5 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 EXF77823.1 - 1.3e-15 57.3 0.0 3.7e-15 55.8 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Pyr_redox_2 PF07992.9 EXF77824.1 - 6.3e-39 133.9 0.5 1.2e-38 133.0 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EXF77824.1 - 2.6e-34 117.5 1.1 8.7e-34 115.8 0.2 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EXF77824.1 - 3.7e-19 68.9 1.8 3e-18 65.9 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF77824.1 - 8.9e-09 35.7 0.0 1.4e-07 31.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF77824.1 - 1.2e-06 27.6 0.0 0.0014 17.5 0.0 2.3 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EXF77824.1 - 0.00071 18.1 4.5 1.8 6.9 0.0 3.1 2 1 1 3 3 3 3 HI0933-like protein FAD_oxidored PF12831.2 EXF77824.1 - 0.054 12.5 0.1 0.054 12.5 0.0 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase GIDA PF01134.17 EXF77824.1 - 0.071 11.9 1.4 0.11 11.3 0.1 2.0 2 1 1 3 3 3 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EXF77824.1 - 0.42 9.3 4.4 4.9 5.8 2.0 2.4 2 0 0 2 2 2 0 FAD binding domain WWbp PF10349.4 EXF77825.1 - 0.031 15.1 0.7 0.047 14.5 0.5 1.2 1 0 0 1 1 1 0 WW-domain ligand protein Herpes_capsid PF06112.6 EXF77825.1 - 6.3 6.8 7.1 11 6.0 4.9 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein MLTD_N PF06474.7 EXF77826.1 - 0.27 11.4 2.4 0.76 10.0 1.6 1.8 1 0 0 1 1 1 0 MltD lipid attachment motif Ribosomal_S8e PF01201.17 EXF77827.1 - 5.5e-48 162.4 2.6 6.6e-48 162.1 1.8 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e SMAP PF15477.1 EXF77827.1 - 0.0016 18.6 3.1 0.0043 17.2 2.1 1.7 1 0 0 1 1 1 1 Small acidic protein family RabGAP-TBC PF00566.13 EXF77828.1 - 2.7e-48 164.2 1.8 2.2e-46 158.0 1.2 2.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain HALZ PF02183.13 EXF77828.1 - 0.12 12.1 16.4 0.12 12.1 1.5 3.2 2 1 1 3 3 3 0 Homeobox associated leucine zipper Microtub_assoc PF07989.6 EXF77828.1 - 0.14 12.0 26.7 0.083 12.7 3.3 3.5 4 0 0 4 4 4 0 Microtubule associated CCDC155 PF14662.1 EXF77828.1 - 0.16 11.5 27.1 0.47 10.0 16.5 2.5 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 DUF1640 PF07798.6 EXF77828.1 - 0.51 10.3 22.4 0.89 9.5 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) ADIP PF11559.3 EXF77828.1 - 2.3 8.0 32.7 1.4 8.8 5.9 3.6 2 1 1 3 3 3 0 Afadin- and alpha -actinin-Binding DUF913 PF06025.7 EXF77830.1 - 3.7e-108 361.6 0.0 3.7e-108 361.6 0.0 4.8 6 0 0 6 6 6 1 Domain of Unknown Function (DUF913) HECT PF00632.20 EXF77830.1 - 6.1e-96 321.3 0.0 1.4e-95 320.0 0.0 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF908 PF06012.7 EXF77830.1 - 7.5e-85 285.1 0.3 7.5e-85 285.1 0.2 2.9 2 0 0 2 2 2 1 Domain of Unknown Function (DUF908) DUF4414 PF14377.1 EXF77830.1 - 9.4e-32 109.1 7.7 9.4e-32 109.1 5.3 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4414) Pribosyl_synth PF14572.1 EXF77831.1 - 4.9e-42 143.7 0.5 2e-36 125.4 0.3 2.4 1 1 1 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EXF77831.1 - 3.4e-34 117.0 0.0 3e-33 114.0 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EXF77831.1 - 7.3e-12 45.1 0.9 1.7e-11 43.9 0.2 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EXF77831.1 - 0.0069 15.6 0.1 0.011 14.9 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Chlorosome_CsmC PF11098.3 EXF77831.1 - 0.12 12.1 1.3 0.23 11.1 0.9 1.4 1 0 0 1 1 1 0 Chlorosome envelope protein C Ribosomal_S6e PF01092.14 EXF77832.1 - 4.6e-63 210.5 0.3 9.6e-63 209.4 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S6e Ctf8 PF09696.5 EXF77833.1 - 3.9e-31 107.3 0.0 4.8e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Ctf8 Glyco_hydro_10 PF00331.15 EXF77834.1 - 4.9e-85 285.3 0.0 5.5e-85 285.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 AP_endonuc_2 PF01261.19 EXF77834.1 - 0.081 12.1 0.1 3.1 7.0 0.0 2.4 2 1 0 2 2 2 0 Xylose isomerase-like TIM barrel Fungal_trans_2 PF11951.3 EXF77835.1 - 0.0012 17.5 0.3 0.2 10.2 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Diphthamide_syn PF01866.12 EXF77836.1 - 1.2e-113 379.4 0.0 1.4e-113 379.2 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein CN_hydrolase PF00795.17 EXF77837.1 - 9.4e-20 70.7 0.0 1.9e-19 69.7 0.0 1.5 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase AA_permease_2 PF13520.1 EXF77839.1 - 1.6e-95 320.1 32.2 2.1e-95 319.7 22.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF77839.1 - 5.7e-22 77.7 28.6 8.3e-22 77.1 19.8 1.2 1 0 0 1 1 1 1 Amino acid permease MFS_1 PF07690.11 EXF77840.1 - 1.3e-14 53.6 51.3 1.3e-14 53.6 35.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Asparaginase_II PF06089.7 EXF77841.1 - 1.6e-108 362.2 0.7 1.8e-108 362.0 0.5 1.0 1 0 0 1 1 1 1 L-asparaginase II GFA PF04828.9 EXF77842.1 - 5.3e-23 80.7 0.6 7.6e-23 80.2 0.4 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Peptidase_C32 PF05411.7 EXF77842.1 - 0.081 12.6 0.0 4.5 6.9 0.0 2.1 1 1 1 2 2 2 0 Equine arteritis virus putative proteinase NOB1_Zn_bind PF08772.6 EXF77842.1 - 0.35 10.7 5.7 1.2 9.0 0.0 2.3 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.6 EXF77842.1 - 7.4 6.1 8.7 0.76 9.3 0.1 2.9 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain Fungal_trans_2 PF11951.3 EXF77843.1 - 0.03 12.9 0.1 0.05 12.1 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF77844.1 - 1.3e-07 31.3 10.6 2.1e-07 30.7 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF77844.1 - 0.0003 19.7 0.5 0.00052 18.9 0.4 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain 2OG-FeII_Oxy_3 PF13640.1 EXF77846.1 - 0.013 15.9 0.1 0.023 15.2 0.1 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Acetyltransf_1 PF00583.19 EXF77847.1 - 2.8e-10 40.0 0.1 9.9e-10 38.3 0.1 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF77847.1 - 8.2e-10 38.7 0.0 3.6e-09 36.6 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EXF77847.1 - 5.1e-06 26.5 0.0 1.2e-05 25.4 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EXF77847.1 - 0.00015 21.4 0.0 0.00026 20.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EXF77847.1 - 0.00029 20.6 0.0 0.0043 16.8 0.0 2.1 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EXF77847.1 - 0.0054 16.5 0.0 0.0093 15.8 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DHDPS PF00701.17 EXF77848.1 - 5.3e-42 143.3 0.0 6.7e-42 143.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF3716 PF12511.3 EXF77849.1 - 9.5e-10 37.9 0.7 1.9e-09 36.9 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) ApbA PF02558.11 EXF77850.1 - 1.7e-32 111.9 0.1 2.2e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EXF77850.1 - 2e-30 105.3 0.0 2.9e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal MFS_1 PF07690.11 EXF77851.1 - 2.6e-37 128.3 31.7 2.6e-37 128.3 22.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF77851.1 - 1.5e-10 40.2 21.7 2.5e-10 39.5 15.0 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter SGL PF08450.7 EXF77852.1 - 5.3e-12 45.6 0.1 9.6e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Str_synth PF03088.11 EXF77852.1 - 0.0011 18.9 0.0 1.3 9.0 0.0 4.0 4 1 0 4 4 4 1 Strictosidine synthase MFS_1 PF07690.11 EXF77853.1 - 2.3e-45 154.8 28.8 2.3e-45 154.8 19.9 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF77853.1 - 6.6e-15 54.6 21.5 1.1e-14 53.9 14.8 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 EXF77853.1 - 0.048 11.7 8.3 0.0065 14.6 2.0 1.9 2 0 0 2 2 2 0 Transmembrane secretion effector OATP PF03137.15 EXF77853.1 - 3.6 5.5 12.9 2.5 6.0 4.8 2.9 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family SLD3 PF08639.5 EXF77854.1 - 2.1 6.9 30.3 2.9 6.4 21.0 1.2 1 0 0 1 1 1 0 DNA replication regulator SLD3 CFEM PF05730.6 EXF77855.1 - 2.7e-10 39.9 8.6 5.2e-10 39.0 6.0 1.5 1 0 0 1 1 1 1 CFEM domain adh_short PF00106.20 EXF77856.1 - 7.1e-16 58.5 0.1 1.2e-15 57.7 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EXF77856.1 - 3.3e-06 26.7 0.0 4.4e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF77856.1 - 6.9e-06 26.1 0.1 1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EXF77856.1 - 1.5e-05 24.7 0.4 2.6e-05 23.9 0.3 1.3 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EXF77856.1 - 0.00073 18.8 0.2 0.0011 18.2 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short_C2 PF13561.1 EXF77856.1 - 0.001 18.8 0.0 0.0026 17.5 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Glyco_transf_4 PF13439.1 EXF77856.1 - 0.029 14.0 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 YjeF_N PF03853.10 EXF77856.1 - 0.055 13.0 0.1 0.13 11.9 0.1 1.5 2 0 0 2 2 2 0 YjeF-related protein N-terminus Sugar_tr PF00083.19 EXF77857.1 - 4.3e-41 140.9 19.7 5.7e-41 140.5 13.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF77857.1 - 2.5e-32 111.9 28.5 3.8e-26 91.6 8.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3433 PF11915.3 EXF77857.1 - 0.0027 17.8 0.6 0.029 14.5 0.1 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3433) PCP_red PF08369.5 EXF77857.1 - 0.036 13.9 0.2 0.091 12.6 0.1 1.7 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit Peptidase_S8 PF00082.17 EXF77858.1 - 3.6e-16 59.1 0.2 6.5e-16 58.3 0.0 1.4 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 EXF77858.1 - 0.0064 17.0 0.1 0.014 15.9 0.0 1.6 2 0 0 2 2 2 1 Peptidase inhibitor I9 Peptidase_S8 PF00082.17 EXF77859.1 - 9.8e-17 60.9 0.5 1.5e-16 60.4 0.3 1.3 1 0 0 1 1 1 1 Subtilase family PA PF02225.17 EXF77859.1 - 9.8e-08 31.6 0.0 2.4e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 PA domain DUF1034 PF06280.7 EXF77859.1 - 6.9e-06 26.4 0.0 6.3e-05 23.3 0.0 2.3 2 1 0 2 2 2 1 Fn3-like domain (DUF1034) Cupin_2 PF07883.6 EXF77860.1 - 3.2e-10 39.3 0.7 5.2e-10 38.6 0.5 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 EXF77860.1 - 1.6e-05 24.6 0.2 1.9e-05 24.3 0.2 1.1 1 0 0 1 1 1 1 Cupin Cupin_1 PF00190.17 EXF77860.1 - 3.5e-05 23.2 0.0 3.9e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Cupin Cupin_7 PF12973.2 EXF77860.1 - 0.00029 20.6 0.0 0.00047 19.9 0.0 1.3 1 0 0 1 1 1 1 ChrR Cupin-like domain AraC_binding PF02311.14 EXF77860.1 - 0.00029 20.5 0.3 0.00037 20.1 0.2 1.1 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_3 PF05899.7 EXF77860.1 - 0.00031 20.0 0.2 0.00043 19.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Amidohydro_1 PF01979.15 EXF77861.1 - 4e-20 72.7 0.1 1.2e-18 67.9 0.1 2.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EXF77861.1 - 2.1e-13 49.8 0.8 6.3e-13 48.3 0.6 1.9 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_4 PF13147.1 EXF77861.1 - 7.9e-10 39.2 0.3 1.9e-05 24.8 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EXF77861.1 - 1.1e-06 28.2 1.9 4.8e-06 26.0 0.0 2.5 3 1 0 3 3 3 1 Amidohydrolase family Acetyltransf_3 PF13302.1 EXF77862.1 - 2.5e-17 63.3 0.0 3.4e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EXF77862.1 - 3.3e-15 55.8 0.1 6.3e-15 54.9 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EXF77862.1 - 5.2e-09 36.1 0.0 6.5e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EXF77862.1 - 1.8e-08 34.5 0.0 2.8e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EXF77862.1 - 4.1e-06 26.8 0.0 7.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EXF77862.1 - 2.3e-05 24.0 0.1 7e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_10 PF13673.1 EXF77862.1 - 0.0015 18.6 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Ank_2 PF12796.2 EXF77864.1 - 1.8e-31 108.2 0.0 8.9e-13 48.3 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EXF77864.1 - 3.5e-30 102.3 0.6 4.5e-07 29.3 0.0 5.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 EXF77864.1 - 1.5e-23 80.5 0.1 0.00031 20.7 0.0 6.2 5 1 1 6 6 6 6 Ankyrin repeat Ank_4 PF13637.1 EXF77864.1 - 3.9e-21 75.0 0.0 2.2e-07 31.1 0.0 4.7 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF77864.1 - 1.5e-20 72.7 0.5 3.3e-05 23.9 0.0 5.5 2 2 4 6 6 6 5 Ankyrin repeats (many copies) HET PF06985.6 EXF77867.1 - 5e-16 59.1 4.0 3.8e-13 49.7 0.2 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) YsaB PF13983.1 EXF77867.1 - 0.14 12.2 0.0 0.27 11.3 0.0 1.4 1 0 0 1 1 1 0 YsaB-like lipoprotein DoxD PF04173.8 EXF77867.1 - 0.24 11.0 0.4 0.42 10.2 0.3 1.3 1 0 0 1 1 1 0 TQO small subunit DoxD Cu_bind_like PF02298.12 EXF77868.1 - 0.00056 19.6 0.3 0.0022 17.7 0.2 1.9 1 1 0 1 1 1 1 Plastocyanin-like domain Copper-bind PF00127.15 EXF77868.1 - 0.035 14.3 0.2 0.094 12.9 0.1 1.6 1 1 0 1 1 1 0 Copper binding proteins, plastocyanin/azurin family PepSY_2 PF13670.1 EXF77868.1 - 0.13 12.1 0.0 0.13 12.1 0.0 2.1 3 0 0 3 3 3 0 Peptidase propeptide and YPEB domain CDK2AP PF09806.4 EXF77868.1 - 3 8.0 10.2 0.21 11.8 2.9 1.8 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein PKD_channel PF08016.7 EXF77869.1 - 6.5e-07 28.1 15.4 5.9e-05 21.6 10.7 2.4 1 1 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 EXF77869.1 - 0.0021 17.3 25.8 0.041 13.1 15.0 2.6 2 1 0 2 2 2 1 Ion transport protein FSH1 PF03959.8 EXF77870.1 - 2.6e-34 118.5 0.0 3.3e-34 118.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EXF77870.1 - 8.9e-05 22.4 0.1 0.078 12.8 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EXF77870.1 - 0.0019 17.6 0.0 0.0026 17.2 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EXF77870.1 - 0.0051 16.5 0.0 0.008 15.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family SSF PF00474.12 EXF77872.1 - 7.5e-17 61.0 27.7 1.1e-16 60.5 19.2 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family FtsJ PF01728.14 EXF77872.1 - 3.4e-11 43.4 0.0 5.8e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF2962 PF11176.3 EXF77872.1 - 0.03 13.8 0.1 0.058 12.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2962) Bac_luciferase PF00296.15 EXF77873.1 - 4.3e-58 196.8 0.3 6.7e-58 196.2 0.2 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase Lactamase_B PF00753.22 EXF77874.1 - 7.7e-07 28.9 2.6 1.7e-06 27.8 1.8 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EXF77874.1 - 0.015 14.8 0.6 0.028 13.9 0.4 1.4 1 0 0 1 1 1 0 Beta-lactamase superfamily domain peroxidase PF00141.18 EXF77875.1 - 2e-30 106.0 0.0 3.3e-30 105.2 0.0 1.3 1 0 0 1 1 1 1 Peroxidase AA_permease_2 PF13520.1 EXF77876.1 - 5.4e-56 189.9 49.2 6.6e-56 189.6 34.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF77876.1 - 1.2e-18 66.7 34.9 1.8e-18 66.1 24.2 1.2 1 0 0 1 1 1 1 Amino acid permease DUF2456 PF10445.4 EXF77876.1 - 0.56 10.1 6.2 0.73 9.7 0.1 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF2456) DUF1772 PF08592.6 EXF77877.1 - 9.2e-06 25.4 2.0 9.8e-06 25.3 0.9 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) MatE PF01554.13 EXF77877.1 - 0.0016 18.0 0.3 0.0029 17.2 0.2 1.4 1 0 0 1 1 1 1 MatE AAA PF00004.24 EXF77878.1 - 2.3e-15 56.9 0.0 6.9e-15 55.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EXF77878.1 - 0.00019 21.0 0.1 0.00044 19.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EXF77878.1 - 0.001 19.1 1.1 0.023 14.8 0.2 2.7 1 1 1 2 2 2 1 AAA domain Macoilin PF09726.4 EXF77878.1 - 0.001 17.4 19.3 0.0015 16.8 13.4 1.3 1 0 0 1 1 1 1 Transmembrane protein AAA_5 PF07728.9 EXF77878.1 - 0.0028 17.3 0.0 0.0077 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EXF77878.1 - 0.0048 17.7 0.0 0.021 15.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EXF77878.1 - 0.016 15.2 0.0 0.041 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 EXF77878.1 - 0.037 13.9 0.0 0.081 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DNA_pol_viral_N PF00242.12 EXF77878.1 - 6.4 5.6 20.5 13 4.7 14.2 1.5 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF3129 PF11327.3 EXF77879.1 - 6.5e-59 198.8 12.3 8e-59 198.5 8.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) DUF3671 PF12420.3 EXF77880.1 - 9.4 6.2 8.0 38 4.3 5.5 2.1 1 1 0 1 1 1 0 Protein of unknown function Acetyltransf_1 PF00583.19 EXF77882.1 - 6.8e-15 54.8 0.0 9.5e-15 54.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF77882.1 - 5.4e-11 42.5 0.0 8.7e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EXF77882.1 - 7.6e-11 42.1 0.0 9.7e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EXF77882.1 - 1.4e-09 38.2 0.0 1.6e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EXF77882.1 - 2.7e-05 23.9 0.0 4.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 EXF77882.1 - 3.8e-05 23.6 0.0 4.9e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EXF77882.1 - 0.00034 20.4 0.0 0.00048 19.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EXF77882.1 - 0.00079 19.1 0.0 0.0012 18.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EXF77882.1 - 0.0067 16.3 0.0 0.0099 15.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 EXF77882.1 - 0.0081 15.5 0.0 0.48 9.7 0.0 2.1 1 1 1 2 2 2 1 GNAT acetyltransferase 2 Acetyltransf_5 PF13444.1 EXF77882.1 - 0.079 13.5 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FAD_binding_4 PF01565.18 EXF77883.1 - 1e-26 93.0 1.2 1e-26 93.0 0.8 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EXF77883.1 - 0.0088 15.9 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF1996 PF09362.5 EXF77884.1 - 1.7e-53 181.7 0.3 2.1e-53 181.3 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) WSC PF01822.14 EXF77885.1 - 1.1e-12 47.6 5.7 1.1e-12 47.6 3.9 3.9 3 1 1 4 4 4 1 WSC domain HET PF06985.6 EXF77887.1 - 3.8e-33 114.5 1.4 2.5e-32 111.9 0.0 2.5 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) UDPGT PF00201.13 EXF77888.1 - 1.5e-10 40.2 0.0 2.4e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EXF77888.1 - 0.088 12.4 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Metallopep PF12044.3 EXF77889.1 - 1.6e-135 451.8 0.0 2.1e-135 451.4 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Reprolysin_2 PF13574.1 EXF77889.1 - 0.0015 18.6 0.3 0.0025 17.8 0.2 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EXF77889.1 - 0.0054 16.6 0.4 0.01 15.7 0.2 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.1 EXF77889.1 - 0.0059 17.1 0.3 0.011 16.2 0.2 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EXF77889.1 - 0.014 14.9 0.2 0.024 14.1 0.2 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.4 EXF77889.1 - 0.065 12.0 0.8 0.11 11.3 0.5 1.2 1 0 0 1 1 1 0 Peptidase M66 TPR_11 PF13414.1 EXF77890.1 - 2.3e-12 46.3 3.3 3.5e-09 36.1 0.1 4.8 5 0 0 5 5 5 1 TPR repeat TPR_2 PF07719.12 EXF77890.1 - 4.4e-10 38.7 5.0 0.0037 17.0 0.0 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EXF77890.1 - 2.6e-07 31.1 8.0 9.6e-05 22.9 0.2 4.9 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EXF77890.1 - 4.8e-07 29.1 0.0 0.0087 15.6 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EXF77890.1 - 8.5e-06 25.6 0.1 0.071 13.0 0.1 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EXF77890.1 - 8.9e-05 21.9 0.0 1.6 8.6 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EXF77890.1 - 0.0019 17.8 0.2 1.4 8.8 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EXF77890.1 - 0.0027 17.5 0.3 0.037 13.8 0.1 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EXF77890.1 - 0.006 17.1 16.2 0.071 13.7 0.0 6.1 5 1 1 6 6 6 2 Tetratricopeptide repeat SHNi-TPR PF10516.4 EXF77890.1 - 0.06 12.6 0.0 0.14 11.4 0.0 1.6 1 0 0 1 1 1 0 SHNi-TPR TPR_6 PF13174.1 EXF77890.1 - 0.13 12.8 0.4 2.1e+02 2.7 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat GYF PF02213.11 EXF77891.1 - 3e-20 71.5 0.1 6.2e-20 70.5 0.0 1.6 1 0 0 1 1 1 1 GYF domain Unstab_antitox PF09720.5 EXF77892.1 - 0.14 11.8 0.1 0.14 11.8 0.1 2.1 2 0 0 2 2 2 0 Putative addiction module component DUF1304 PF06993.7 EXF77893.1 - 2.7e-37 126.9 0.6 3.1e-37 126.7 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1304) Dynamin_N PF00350.18 EXF77894.1 - 2.6e-17 63.1 2.3 3.1e-17 62.9 0.0 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EXF77894.1 - 1.4e-05 25.0 0.1 0.00027 20.8 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EXF77894.1 - 7.4e-05 22.8 0.0 0.022 14.7 0.0 3.1 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EXF77894.1 - 0.00039 19.6 0.0 0.0073 15.4 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EXF77894.1 - 0.0015 18.8 0.0 0.0015 18.8 0.0 2.8 2 1 0 2 2 1 1 ABC transporter Miro PF08477.8 EXF77894.1 - 0.0074 16.7 0.0 0.031 14.7 0.0 2.1 2 0 0 2 2 1 1 Miro-like protein AAA_22 PF13401.1 EXF77894.1 - 0.013 15.6 0.1 0.19 11.8 0.0 3.0 2 1 1 3 3 3 0 AAA domain CENP-F_leu_zip PF10473.4 EXF77894.1 - 0.019 14.8 14.9 0.089 12.6 0.6 3.4 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IIGP PF05049.8 EXF77894.1 - 0.032 13.0 0.0 0.064 12.0 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AIG1 PF04548.11 EXF77894.1 - 0.049 12.7 2.3 0.14 11.2 0.0 2.6 3 0 0 3 3 3 0 AIG1 family AAA_29 PF13555.1 EXF77894.1 - 0.082 12.4 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EXF77894.1 - 0.095 13.5 2.7 0.16 12.7 0.0 2.7 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.1 EXF77894.1 - 0.14 12.0 2.7 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF972 PF06156.8 EXF77894.1 - 0.16 12.3 3.9 11 6.4 0.4 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF972) Rho_Binding PF08912.6 EXF77894.1 - 0.22 11.8 5.6 11 6.4 0.1 2.8 2 0 0 2 2 2 0 Rho Binding TBPIP PF07106.8 EXF77894.1 - 0.47 9.9 14.1 0.56 9.7 0.2 3.6 5 0 0 5 5 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Pox_A_type_inc PF04508.7 EXF77894.1 - 0.47 10.3 4.5 3.1 7.8 3.1 2.5 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat L31 PF09784.4 EXF77894.1 - 2.1 8.4 7.5 0.43 10.6 0.2 3.4 5 0 0 5 5 5 0 Mitochondrial ribosomal protein L31 Cortex-I_coil PF09304.5 EXF77894.1 - 7.4 6.6 15.5 0.28 11.2 2.4 3.8 5 0 0 5 5 5 0 Cortexillin I, coiled coil Prp19_bind PF06991.6 EXF77896.1 - 0.18 11.0 1.5 0.27 10.4 1.0 1.2 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain Beta-lactamase PF00144.19 EXF77897.1 - 2.6e-50 171.3 1.1 3.4e-50 170.9 0.8 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3425 PF11905.3 EXF77898.1 - 1.9e-21 76.3 0.0 4.2e-21 75.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Mto2_bdg PF12808.2 EXF77898.1 - 2.3e-05 24.3 0.8 0.00024 21.1 1.2 2.0 2 0 0 2 2 2 1 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF837 PF05769.6 EXF77898.1 - 0.0023 17.5 0.4 0.0042 16.6 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF837) CCDC144C PF14915.1 EXF77898.1 - 0.0062 15.4 2.4 0.011 14.7 1.7 1.3 1 0 0 1 1 1 1 CCDC144C protein coiled-coil region YPEB PF14620.1 EXF77898.1 - 0.028 13.4 0.3 0.051 12.5 0.2 1.4 1 0 0 1 1 1 0 YpeB sporulation DUF1471 PF07338.8 EXF77898.1 - 0.051 13.2 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1471) DUF904 PF06005.7 EXF77898.1 - 0.08 13.2 2.9 0.18 12.1 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF904) Leu_zip PF15294.1 EXF77898.1 - 0.12 11.4 1.5 0.2 10.7 1.0 1.3 1 0 0 1 1 1 0 Leucine zipper DUF720 PF05302.6 EXF77898.1 - 0.32 10.7 2.4 0.6 9.8 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF720) Beta_elim_lyase PF01212.16 EXF77899.1 - 9e-43 146.4 0.1 1.1e-42 146.1 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EXF77899.1 - 6.7e-06 25.2 0.0 8.4e-06 24.9 0.0 1.2 1 1 0 1 1 1 1 Aminotransferase class I and II Toprim PF01751.17 EXF77899.1 - 0.0054 16.6 0.0 0.013 15.4 0.0 1.5 1 1 0 1 1 1 1 Toprim domain AhpC-TSA_2 PF13911.1 EXF77900.1 - 5.7e-08 32.6 0.0 8.1e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EXF77900.1 - 0.00015 21.4 0.0 0.00018 21.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EXF77900.1 - 0.0012 18.4 0.0 0.0025 17.3 0.0 1.5 2 0 0 2 2 2 1 Redoxin ABC_tran PF00005.22 EXF77901.1 - 1.6e-47 161.2 0.2 8.4e-24 84.4 0.0 3.8 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EXF77901.1 - 1.5e-17 64.4 0.0 0.00071 19.6 0.0 4.5 4 0 0 4 4 4 4 AAA domain SMC_N PF02463.14 EXF77901.1 - 3.9e-16 58.9 0.3 1.4e-05 24.4 0.0 4.0 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EXF77901.1 - 1.2e-09 37.5 0.0 0.0013 18.2 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EXF77901.1 - 9.6e-09 34.6 0.1 8.5e-05 21.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EXF77901.1 - 4.1e-08 34.0 0.1 0.0072 17.1 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_23 PF13476.1 EXF77901.1 - 5.5e-08 33.3 8.1 0.00031 21.1 0.0 3.2 4 0 0 4 4 2 2 AAA domain AAA_22 PF13401.1 EXF77901.1 - 1.6e-07 31.5 0.0 0.0016 18.5 0.0 3.3 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 EXF77901.1 - 3.3e-07 30.2 0.0 0.0037 17.1 0.0 3.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_28 PF13521.1 EXF77901.1 - 6.3e-07 29.4 0.0 0.018 14.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EXF77901.1 - 1.8e-06 27.6 0.5 0.26 10.7 0.0 4.1 4 1 0 4 4 4 2 AAA-like domain AAA_33 PF13671.1 EXF77901.1 - 3.9e-06 26.7 0.0 0.13 12.1 0.0 3.1 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.1 EXF77901.1 - 5e-06 26.3 0.0 0.024 14.5 0.0 3.4 3 2 0 3 3 2 2 Putative exonuclease SbcCD, C subunit Miro PF08477.8 EXF77901.1 - 7.1e-06 26.5 0.0 0.027 14.9 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_15 PF13175.1 EXF77901.1 - 8.4e-06 25.0 6.8 0.087 11.8 0.0 5.0 4 2 1 5 5 5 1 AAA ATPase domain AAA_18 PF13238.1 EXF77901.1 - 8.5e-06 26.0 1.3 0.16 12.3 0.0 4.1 4 0 0 4 4 2 2 AAA domain Dynamin_N PF00350.18 EXF77901.1 - 9.5e-06 25.5 0.0 0.0022 17.8 0.0 3.0 2 0 0 2 2 2 1 Dynamin family AAA PF00004.24 EXF77901.1 - 1.5e-05 25.2 0.0 0.36 11.0 0.0 4.1 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EXF77901.1 - 1.6e-05 24.6 0.0 0.27 10.9 0.0 3.0 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EXF77901.1 - 5.1e-05 22.7 0.1 0.083 12.3 0.0 3.0 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ArgK PF03308.11 EXF77901.1 - 5.6e-05 22.0 1.2 0.21 10.3 0.0 2.7 3 0 0 3 3 3 2 ArgK protein RNA_helicase PF00910.17 EXF77901.1 - 6.3e-05 23.1 0.0 0.79 9.9 0.0 3.1 2 0 0 2 2 2 2 RNA helicase AAA_16 PF13191.1 EXF77901.1 - 7.2e-05 22.8 0.5 1 9.3 0.0 4.1 4 0 0 4 4 4 1 AAA ATPase domain NACHT PF05729.7 EXF77901.1 - 0.00022 20.9 0.1 0.095 12.3 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_14 PF13173.1 EXF77901.1 - 0.00033 20.5 0.0 1.8 8.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EXF77901.1 - 0.00041 20.1 0.0 1.2 8.7 0.0 3.3 3 0 0 3 3 2 2 Archaeal ATPase DUF87 PF01935.12 EXF77901.1 - 0.00084 19.2 0.9 0.98 9.1 0.0 4.0 5 0 0 5 5 4 1 Domain of unknown function DUF87 AAA_13 PF13166.1 EXF77901.1 - 0.0011 17.4 4.7 1.4 7.3 0.0 3.8 4 1 0 4 4 4 2 AAA domain cobW PF02492.14 EXF77901.1 - 0.0015 17.9 0.7 2.1 7.7 0.0 3.5 4 0 0 4 4 3 1 CobW/HypB/UreG, nucleotide-binding domain MutS_V PF00488.16 EXF77901.1 - 0.0052 16.2 0.1 0.76 9.1 0.0 2.4 2 0 0 2 2 2 1 MutS domain V ATP-synt_ab PF00006.20 EXF77901.1 - 0.0053 16.2 0.0 3.4 7.1 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_30 PF13604.1 EXF77901.1 - 0.0064 16.0 0.0 6 6.3 0.0 3.1 3 0 0 3 3 3 0 AAA domain Septin PF00735.13 EXF77901.1 - 0.0087 15.1 0.2 1.9 7.4 0.0 3.0 3 0 0 3 3 3 1 Septin AAA_25 PF13481.1 EXF77901.1 - 0.0096 15.3 0.0 7.6 5.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain Rad17 PF03215.10 EXF77901.1 - 0.015 14.0 0.0 1.2 7.7 0.0 2.2 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein ATP_bind_1 PF03029.12 EXF77901.1 - 0.016 14.7 0.0 7.7 5.9 0.0 2.8 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein MMS19_N PF14500.1 EXF77901.1 - 0.017 14.3 0.3 0.17 11.0 0.1 2.4 2 0 0 2 2 2 0 Dos2-interacting transcription regulator of RNA-Pol-II G-alpha PF00503.15 EXF77901.1 - 0.02 13.5 0.7 1.1 7.8 0.0 3.1 3 0 0 3 3 3 0 G-protein alpha subunit PRK PF00485.13 EXF77901.1 - 0.025 14.1 0.0 1 8.8 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Mg_chelatase PF01078.16 EXF77901.1 - 0.027 13.6 0.0 2.7 7.1 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 EXF77901.1 - 0.044 13.2 0.6 4.8 6.5 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family HEAT PF02985.17 EXF77901.1 - 0.059 13.4 0.3 54 4.2 0.0 3.9 3 0 0 3 3 3 0 HEAT repeat T4_Gp59_C PF08994.5 EXF77902.1 - 0.2 11.8 0.0 0.64 10.2 0.0 1.8 1 0 0 1 1 1 0 T4 gene Gp59 loader of gp41 DNA helicase C-term AF-4 PF05110.8 EXF77902.1 - 8.6 4.0 6.9 12 3.5 4.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein p450 PF00067.17 EXF77903.1 - 1.3e-37 129.4 0.0 1.6e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ApbA_C PF08546.6 EXF77903.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Dioxygenase_C PF00775.16 EXF77904.1 - 9.9e-12 44.4 0.0 7.8e-10 38.3 0.0 2.3 1 1 1 2 2 2 2 Dioxygenase HET PF06985.6 EXF77905.1 - 5.4e-21 75.2 0.0 1.3e-20 73.9 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RNase_H PF00075.19 EXF77906.1 - 7.9e-14 52.1 0.0 1.9e-13 50.8 0.0 1.6 1 1 0 1 1 1 1 RNase H RVT_3 PF13456.1 EXF77906.1 - 1.7e-05 24.5 0.1 0.0068 16.1 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase-like Cellulase PF00150.13 EXF77907.1 - 4.6e-12 45.7 0.0 0.00011 21.5 0.0 2.9 2 1 0 2 2 2 2 Cellulase (glycosyl hydrolase family 5) Aldo_ket_red PF00248.16 EXF77908.1 - 6.4e-48 163.0 0.0 8.4e-48 162.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family XH PF03469.9 EXF77908.1 - 0.029 14.0 1.2 0.058 13.0 0.1 2.0 2 0 0 2 2 2 0 XH domain Glyco_hydro_47 PF01532.15 EXF77910.1 - 5.3e-160 532.9 0.0 6.5e-160 532.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 YcfA PF07927.7 EXF77911.1 - 0.78 9.6 3.3 0.32 10.9 0.3 1.9 2 0 0 2 2 2 0 YcfA-like protein DUF3433 PF11915.3 EXF77912.1 - 2e-30 104.7 8.0 9.6e-18 64.1 1.6 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) tRNA-synt_1c PF00749.16 EXF77915.1 - 1.5e-99 332.6 0.0 2.1e-99 332.1 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EXF77915.1 - 1.5e-32 112.6 0.1 1.9e-31 109.0 0.0 2.6 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain Macro PF01661.16 EXF77916.1 - 2.7e-38 130.5 0.2 4.6e-38 129.7 0.1 1.4 1 0 0 1 1 1 1 Macro domain Peptidase_S41 PF03572.13 EXF77917.1 - 8.4e-05 22.0 0.0 0.00033 20.1 0.0 2.0 2 1 0 2 2 2 1 Peptidase family S41 Lipocalin_5 PF13924.1 EXF77918.1 - 2.1e-21 76.0 0.0 3.9e-21 75.1 0.0 1.4 1 0 0 1 1 1 1 Lipocalin-like domain NACHT PF05729.7 EXF77918.1 - 3.1e-10 39.9 0.0 8.9e-10 38.4 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EXF77918.1 - 0.00083 19.5 0.2 0.0045 17.1 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_10 PF12846.2 EXF77918.1 - 0.0014 18.1 0.3 0.0098 15.3 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_16 PF13191.1 EXF77918.1 - 0.0022 18.0 0.0 0.0088 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.10 EXF77918.1 - 0.0036 17.0 0.5 0.22 11.2 0.0 2.4 2 0 0 2 2 2 1 NTPase ABC_tran PF00005.22 EXF77918.1 - 0.0052 17.0 0.1 0.016 15.4 0.1 1.8 1 0 0 1 1 1 1 ABC transporter AAA_23 PF13476.1 EXF77918.1 - 0.0052 17.1 0.2 0.0052 17.1 0.2 2.0 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EXF77918.1 - 0.0058 17.4 0.1 0.033 15.0 0.0 2.4 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.1 EXF77918.1 - 0.021 14.3 0.1 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EXF77918.1 - 0.026 14.8 0.0 0.071 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EXF77918.1 - 0.062 12.3 0.0 11 5.0 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 EXF77918.1 - 0.11 12.2 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain RNA_helicase PF00910.17 EXF77918.1 - 0.2 11.8 0.0 0.48 10.6 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AA_permease PF00324.16 EXF77919.1 - 6e-38 130.3 32.1 4.5e-24 84.6 16.0 2.0 2 0 0 2 2 2 2 Amino acid permease AA_permease_2 PF13520.1 EXF77919.1 - 5.5e-29 100.9 20.0 7.9e-29 100.4 13.9 1.1 1 0 0 1 1 1 1 Amino acid permease Lig_chan PF00060.21 EXF77919.1 - 0.032 13.9 0.0 0.26 11.0 0.0 2.6 2 1 0 2 2 2 0 Ligand-gated ion channel DUF2061 PF09834.4 EXF77919.1 - 2.7 8.2 15.2 1.6 8.9 0.3 4.0 3 0 0 3 3 3 0 Predicted membrane protein (DUF2061) Pkinase PF00069.20 EXF77921.1 - 5e-24 84.8 0.0 1.1e-23 83.6 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF77921.1 - 1.4e-15 57.0 0.0 3.2e-14 52.6 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EXF77921.1 - 0.03 13.1 0.0 0.064 12.0 0.0 1.5 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Epimerase PF01370.16 EXF77922.1 - 2e-21 76.5 0.0 2.8e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EXF77922.1 - 4.2e-09 35.6 0.0 7.2e-09 34.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EXF77922.1 - 1.6e-07 31.3 0.0 9.2e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase Saccharop_dh PF03435.13 EXF77922.1 - 0.00031 19.8 0.0 0.00048 19.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EXF77922.1 - 0.00092 17.9 0.0 0.0031 16.2 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EXF77922.1 - 0.0012 18.8 0.0 0.0038 17.2 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EXF77922.1 - 0.0028 17.3 0.0 0.0046 16.6 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EXF77922.1 - 0.049 12.5 0.0 0.1 11.4 0.0 1.6 1 0 0 1 1 1 0 Male sterility protein TrkA_N PF02254.13 EXF77922.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain NmrA PF05368.8 EXF77922.1 - 0.059 12.6 0.0 0.093 11.9 0.0 1.3 1 0 0 1 1 1 0 NmrA-like family CBS PF00571.23 EXF77924.1 - 6.6e-05 22.6 0.1 0.41 10.4 0.0 3.1 1 1 1 2 2 2 2 CBS domain Spindle_Spc25 PF08234.7 EXF77924.1 - 0.039 13.9 0.0 0.11 12.4 0.0 1.7 2 0 0 2 2 2 0 Chromosome segregation protein Spc25 Mito_carr PF00153.22 EXF77925.1 - 3.2e-49 164.5 9.0 6e-18 64.3 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Methyltransf_23 PF13489.1 EXF77926.1 - 5.8e-11 42.3 0.0 6.6e-10 38.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF77926.1 - 0.00024 21.5 0.0 0.0067 16.8 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF77926.1 - 0.0012 17.9 0.1 0.58 9.2 0.0 2.2 1 1 1 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EXF77926.1 - 0.0015 18.9 0.0 0.05 14.0 0.0 2.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF77926.1 - 0.0051 16.4 0.0 2.1 7.9 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Pyr_redox_3 PF13738.1 EXF77927.1 - 1e-05 25.6 0.0 7.7e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.17 EXF77928.1 - 2.3e-28 98.9 0.0 1.6e-26 92.8 0.0 2.3 1 1 0 1 1 1 1 Cytochrome P450 PSD5 PF07637.6 EXF77928.1 - 0.13 12.3 0.1 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1595) EST1_DNA_bind PF10373.4 EXF77929.1 - 1.9e-16 60.0 0.0 6.1e-16 58.4 0.0 1.9 1 1 0 1 1 1 1 Est1 DNA/RNA binding domain Nup188 PF10487.4 EXF77929.1 - 0.15 9.9 0.0 0.21 9.4 0.0 1.1 1 0 0 1 1 1 0 Nucleoporin subcomplex protein binding to Pom34 Fungal_trans PF04082.13 EXF77931.1 - 1.1e-17 63.7 0.1 1.9e-17 62.9 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF77931.1 - 5.1e-07 29.4 8.9 1e-06 28.5 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-H2C2_2 PF13465.1 EXF77932.1 - 0.0042 17.3 0.2 0.0042 17.3 0.2 4.1 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EXF77932.1 - 0.0045 17.2 26.7 0.022 15.0 0.8 4.8 4 1 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF77932.1 - 0.014 15.7 1.1 0.014 15.7 0.7 4.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EXF77932.1 - 2.8 8.1 10.7 0.28 11.3 1.1 3.5 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding Fungal_trans PF04082.13 EXF77936.1 - 4.1e-27 94.6 0.0 6.6e-27 94.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF77936.1 - 8.5e-06 25.5 15.8 1.4e-05 24.8 10.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DHquinase_I PF01487.10 EXF77939.1 - 5.3e-55 186.5 0.0 8.3e-55 185.8 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase MFS_1 PF07690.11 EXF77940.1 - 1.1e-34 119.7 51.1 1.1e-34 119.7 35.4 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF77940.1 - 4.6e-11 41.9 10.3 4.6e-11 41.9 7.1 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter OATP PF03137.15 EXF77940.1 - 0.0042 15.1 2.6 0.012 13.7 1.8 1.7 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Glyco_transf_90 PF05686.7 EXF77942.1 - 2.4e-08 33.1 0.0 0.00058 18.6 0.0 3.0 3 0 0 3 3 3 2 Glycosyl transferase family 90 Tctex-1 PF03645.8 EXF77944.1 - 9.1e-34 115.3 0.0 1.1e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Tctex-1 family DDE_Tnp_4 PF13359.1 EXF77944.1 - 0.13 11.8 0.1 0.17 11.4 0.1 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF202 PF02656.10 EXF77945.1 - 1.8e-13 50.5 5.9 2.2e-13 50.2 2.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF1430 PF07242.6 EXF77945.1 - 0.18 11.8 1.2 3.3 7.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Phageshock_PspG PF09583.5 EXF77945.1 - 0.32 11.0 0.3 0.32 11.0 0.2 2.4 3 0 0 3 3 3 0 Phage shock protein G (Phageshock_PspG) 7TMR-DISM_7TM PF07695.6 EXF77945.1 - 1.2 8.7 9.3 4.6 6.8 6.5 1.8 1 1 0 1 1 1 0 7TM diverse intracellular signalling Alba PF01918.16 EXF77946.1 - 0.0071 15.9 0.2 0.019 14.5 0.1 1.8 2 0 0 2 2 2 1 Alba Menin PF05053.8 EXF77946.1 - 0.15 10.2 1.5 0.21 9.7 1.0 1.2 1 0 0 1 1 1 0 Menin Pkinase PF00069.20 EXF77948.1 - 9.7e-59 198.6 0.0 1.3e-58 198.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF77948.1 - 4.6e-31 107.8 0.0 5.9e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF77948.1 - 5.5e-06 25.5 0.0 4.8e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EXF77948.1 - 0.0019 17.9 0.0 0.0048 16.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EXF77948.1 - 0.0038 16.3 0.0 0.0071 15.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EXF77948.1 - 0.14 11.7 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pox_ser-thr_kin PF05445.6 EXF77948.1 - 0.22 10.2 0.0 0.42 9.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PAT1 PF09770.4 EXF77948.1 - 2.6 6.1 5.1 3.7 5.6 3.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Fungal_trans PF04082.13 EXF77950.1 - 2.4e-06 26.6 0.0 5.4e-06 25.4 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF4611 PF15387.1 EXF77950.1 - 0.53 10.4 2.9 1.4 9.0 2.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) GFO_IDH_MocA PF01408.17 EXF77951.1 - 4.4e-17 62.7 0.1 9.4e-17 61.6 0.1 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sema PF01403.14 EXF77951.1 - 0.015 13.8 0.0 0.021 13.3 0.0 1.1 1 0 0 1 1 1 0 Sema domain NAD_binding_3 PF03447.11 EXF77951.1 - 0.043 14.2 0.1 0.064 13.6 0.1 1.3 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EXF77952.1 - 6.3e-18 65.4 0.0 1.3e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EXF77952.1 - 0.12 12.1 0.0 0.36 10.6 0.0 1.9 1 0 0 1 1 1 0 Oxidoreductase family, C-terminal alpha/beta domain RTA1 PF04479.8 EXF77953.1 - 1.2e-43 149.2 2.8 2e-43 148.4 1.9 1.3 1 0 0 1 1 1 1 RTA1 like protein 2TM PF13239.1 EXF77953.1 - 0.35 10.9 7.0 1.2 9.2 0.3 3.6 2 2 0 2 2 2 0 2TM domain DUF4271 PF14093.1 EXF77953.1 - 2.4 7.7 11.3 0.15 11.7 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) DUF3792 PF12670.2 EXF77953.1 - 3.2 7.6 11.3 0.16 11.8 2.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) DUF4131 PF13567.1 EXF77953.1 - 5.2 6.4 14.0 1.9 7.8 0.2 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) ABC2_membrane_4 PF12730.2 EXF77953.1 - 6.3 5.8 22.5 3.6 6.6 0.3 3.3 2 1 1 3 3 3 0 ABC-2 family transporter protein ketoacyl-synt PF00109.21 EXF77954.1 - 9.8e-64 215.2 0.1 2.3e-62 210.7 0.0 2.0 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EXF77954.1 - 4e-18 65.3 0.2 1.2e-17 63.9 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EXF77954.1 - 0.091 11.7 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Thiolase, N-terminal domain Carn_acyltransf PF00755.15 EXF77955.1 - 5.3e-79 265.8 0.0 7.7e-79 265.3 0.0 1.2 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase Acyl_transf_1 PF00698.16 EXF77955.1 - 6.4e-59 199.8 0.0 1.2e-58 198.9 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EXF77955.1 - 3.3e-53 180.0 0.0 8e-53 178.7 0.0 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EXF77955.1 - 8e-48 163.1 0.0 1.6e-47 162.0 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EXF77955.1 - 7.2e-43 146.3 0.6 3.4e-42 144.1 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.21 EXF77955.1 - 9.1e-15 54.3 0.0 5.6e-14 51.7 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF77955.1 - 2.3e-14 54.3 0.0 2.4e-13 51.0 0.0 2.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EXF77955.1 - 3.6e-07 30.3 1.0 2.3e-06 27.7 0.1 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_12 PF08242.7 EXF77955.1 - 0.0017 18.8 0.0 0.0058 17.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_10 PF13460.1 EXF77955.1 - 0.002 18.1 1.2 0.11 12.4 0.0 3.2 3 0 0 3 3 3 1 NADH(P)-binding Collagen PF01391.13 EXF77955.1 - 0.035 13.6 2.5 0.073 12.6 1.7 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Mod_r PF07200.8 EXF77955.1 - 0.15 11.9 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein MFS_1 PF07690.11 EXF77956.1 - 4.4e-25 88.1 35.4 5.1e-22 78.0 10.4 2.5 3 0 0 3 3 3 2 Major Facilitator Superfamily FAD_binding_4 PF01565.18 EXF77957.1 - 3e-20 72.1 3.6 6.3e-20 71.0 2.5 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF77957.1 - 4.4e-10 39.3 0.0 1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like DUF427 PF04248.7 EXF77958.1 - 3.5e-35 119.5 0.5 1.5e-28 98.3 0.1 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF427) DUF3425 PF11905.3 EXF77959.1 - 5.9e-18 65.0 1.7 5.9e-18 65.0 1.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) WD40_alt PF14077.1 EXF77959.1 - 0.22 11.1 0.8 0.53 9.9 0.6 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif p450 PF00067.17 EXF77960.1 - 5.6e-59 199.8 0.0 3.7e-58 197.1 0.0 2.1 1 1 0 1 1 1 1 Cytochrome P450 ADH_N PF08240.7 EXF77961.1 - 2e-24 85.4 1.7 3.7e-24 84.5 1.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF77961.1 - 4.1e-20 71.6 0.0 6.2e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF77961.1 - 0.041 14.7 0.0 0.081 13.8 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Aldedh PF00171.17 EXF77962.1 - 1.5e-149 498.3 0.0 1.7e-149 498.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EXF77962.1 - 0.054 12.2 0.0 0.15 10.7 0.0 1.8 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF2108 PF09881.4 EXF77962.1 - 0.15 11.9 0.3 0.27 11.0 0.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2108) FAD_binding_3 PF01494.14 EXF77963.1 - 5e-33 114.6 0.0 2.7e-32 112.2 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF77963.1 - 4.9e-09 35.5 0.2 5.3e-05 22.2 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF77963.1 - 2.3e-06 27.5 0.2 5.8e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EXF77963.1 - 6.8e-06 25.2 0.1 0.025 13.5 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox PF00070.22 EXF77963.1 - 8.1e-06 26.1 0.1 0.0042 17.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EXF77963.1 - 4.8e-05 22.6 0.0 0.16 11.0 0.0 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 EXF77963.1 - 7.4e-05 22.7 0.3 0.00081 19.3 0.2 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF77963.1 - 0.00028 19.5 0.1 0.23 9.8 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 EXF77963.1 - 0.00036 20.6 0.0 0.001 19.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF77963.1 - 0.00092 18.1 0.1 0.0018 17.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EXF77963.1 - 0.043 12.8 0.1 0.079 12.0 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Trp_halogenase PF04820.9 EXF77963.1 - 0.047 12.3 0.1 6 5.3 0.0 2.4 3 0 0 3 3 3 0 Tryptophan halogenase GIDA PF01134.17 EXF77963.1 - 0.22 10.3 0.1 0.41 9.4 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Cutinase PF01083.17 EXF77964.1 - 1.1e-45 155.5 0.8 1.4e-45 155.2 0.6 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EXF77964.1 - 0.00012 21.6 0.2 0.00027 20.4 0.0 1.6 2 0 0 2 2 2 1 PE-PPE domain VirJ PF06057.6 EXF77964.1 - 0.009 15.8 0.0 0.016 14.9 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) DUF2974 PF11187.3 EXF77964.1 - 0.026 13.9 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) DUF676 PF05057.9 EXF77964.1 - 0.032 13.5 0.0 0.33 10.2 0.0 2.1 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EXF77964.1 - 0.066 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_2 PF02230.11 EXF77964.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase AA_permease PF00324.16 EXF77965.1 - 1.1e-121 406.5 37.6 1.3e-121 406.2 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF77965.1 - 6e-28 97.5 39.6 7.3e-28 97.2 27.4 1.0 1 0 0 1 1 1 1 Amino acid permease Erf4 PF10256.4 EXF77966.1 - 9.6e-07 28.6 0.0 2.5e-06 27.3 0.0 1.7 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF4646 PF15496.1 EXF77966.1 - 0.024 14.6 0.0 0.07 13.1 0.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4646) FAD_binding_4 PF01565.18 EXF77967.1 - 2.8e-17 62.4 3.0 2.8e-17 62.4 2.1 2.3 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EXF77967.1 - 3e-12 46.2 1.6 5.6e-12 45.3 0.2 2.1 2 0 0 2 2 2 1 Berberine and berberine like Cytokin-bind PF09265.5 EXF77967.1 - 0.033 13.3 0.7 0.11 11.5 0.5 1.7 1 1 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding CFEM PF05730.6 EXF77968.1 - 1.6e-12 47.0 12.0 1.6e-12 47.0 8.3 1.7 2 0 0 2 2 2 1 CFEM domain Defensin_2 PF01097.13 EXF77968.1 - 0.00075 19.1 3.4 0.0024 17.5 2.4 1.9 1 0 0 1 1 1 1 Arthropod defensin Gamma-thionin PF00304.15 EXF77968.1 - 0.0036 17.2 2.2 0.0036 17.2 1.5 1.8 2 0 0 2 2 2 1 Gamma-thionin family Rad54_N PF08658.5 EXF77968.1 - 0.2 11.3 0.4 0.3 10.8 0.3 1.1 1 0 0 1 1 1 0 Rad54 N terminal Ank_2 PF12796.2 EXF77969.1 - 1.2e-30 105.7 3.2 5.3e-09 36.2 0.0 5.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EXF77969.1 - 1.1e-24 85.8 4.2 2.5e-08 33.9 0.1 5.8 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 EXF77969.1 - 7.1e-21 72.9 2.9 1.3e-06 27.9 0.1 7.7 8 0 0 8 8 8 3 Ankyrin repeat Ank_3 PF13606.1 EXF77969.1 - 1.1e-20 71.6 3.1 0.00068 19.6 0.1 8.0 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.1 EXF77969.1 - 5e-18 65.1 7.2 1.4e-06 28.6 0.1 7.0 4 1 4 8 8 8 5 Ankyrin repeats (many copies) Metallophos PF00149.23 EXF77970.1 - 1.1e-08 34.6 0.5 4.8e-08 32.6 0.1 2.2 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EXF77970.1 - 8.5e-07 28.9 0.0 1.6e-06 28.0 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Trypsin_2 PF13365.1 EXF77971.1 - 2.5e-10 40.3 0.1 1.3e-09 38.0 0.0 2.2 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.21 EXF77971.1 - 7.8e-10 38.7 0.1 2.3e-09 37.1 0.1 1.7 1 1 0 1 1 1 1 Trypsin Peptidase_C3 PF00548.15 EXF77971.1 - 0.024 14.4 0.3 0.049 13.4 0.2 1.5 1 0 0 1 1 1 0 3C cysteine protease (picornain 3C) Peptidase_C4 PF00863.14 EXF77971.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C4 Birna_VP4 PF01768.11 EXF77971.1 - 0.17 10.8 2.8 0.093 11.7 0.2 1.8 2 0 0 2 2 2 0 Birnavirus VP4 protein Pectinesterase PF01095.14 EXF77973.1 - 1.8e-48 164.6 10.4 2.4e-48 164.2 7.2 1.1 1 0 0 1 1 1 1 Pectinesterase Methyltransf_PK PF05891.7 EXF77974.1 - 1.7e-83 279.1 0.0 2e-83 279.0 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 EXF77974.1 - 0.00042 20.0 0.0 0.00066 19.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain SR-25 PF10500.4 EXF77975.1 - 0.053 12.9 12.0 0.077 12.4 8.3 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein KAT11 PF08214.6 EXF77975.1 - 0.18 10.8 1.0 0.23 10.5 0.7 1.1 1 0 0 1 1 1 0 Histone acetylation protein TP53IP5 PF15331.1 EXF77975.1 - 0.21 11.4 4.4 0.27 11.0 3.1 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 TAF1D PF15333.1 EXF77975.1 - 0.32 10.7 7.2 0.41 10.4 5.0 1.1 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D ABC_tran_2 PF12848.2 EXF77975.1 - 0.6 9.9 0.1 0.6 9.9 0.1 2.2 2 0 0 2 2 2 0 ABC transporter SRP-alpha_N PF04086.8 EXF77975.1 - 0.86 8.9 10.3 1.2 8.4 7.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Rtf2 PF04641.7 EXF77975.1 - 1.3 8.1 11.8 1.9 7.6 8.2 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger DUF4603 PF15376.1 EXF77975.1 - 2.4 5.2 5.4 2.8 4.9 3.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) NARP1 PF12569.3 EXF77975.1 - 6.6 5.3 12.0 7.9 5.1 8.3 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Polysacc_deac_1 PF01522.16 EXF77977.1 - 7.8e-24 83.6 0.1 1.4e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EXF77977.1 - 2.7e-20 72.0 196.0 1.2e-06 28.4 18.5 9.2 8 1 1 9 9 9 6 Chitin recognition protein CompInhib_SCIN PF11546.3 EXF77977.1 - 0.25 11.2 0.1 0.76 9.6 0.1 1.8 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN ARGLU PF15346.1 EXF77978.1 - 0.017 14.8 24.1 1.4 8.7 16.6 2.4 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 U79_P34 PF03064.11 EXF77978.1 - 0.54 9.7 15.8 1.1 8.6 11.0 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 RNA_polI_A34 PF08208.6 EXF77978.1 - 0.64 9.6 16.3 0.073 12.7 8.1 1.8 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 DDHD PF02862.12 EXF77978.1 - 1.2 8.8 6.4 2.1 8.0 4.4 1.4 1 0 0 1 1 1 0 DDHD domain RNase_H2-Ydr279 PF09468.5 EXF77978.1 - 3.4 6.7 10.1 5.6 6.0 7.0 1.4 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) CDC45 PF02724.9 EXF77978.1 - 6.3 4.6 12.3 8.1 4.3 8.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 EXF77978.1 - 7.5 4.1 10.3 9.5 3.7 7.2 1.1 1 0 0 1 1 1 0 Ycf1 Rtf2 PF04641.7 EXF77978.1 - 10 5.2 18.0 14 4.7 12.5 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger TPR_2 PF07719.12 EXF77980.1 - 1.3e-09 37.1 3.3 0.032 14.1 0.1 7.1 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_14 PF13428.1 EXF77980.1 - 7.3e-08 32.3 10.2 0.042 14.4 0.0 7.4 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_16 PF13432.1 EXF77980.1 - 1.1e-06 29.0 12.3 0.21 12.3 0.9 6.0 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EXF77980.1 - 3.3e-06 26.4 1.2 1.6 8.4 0.0 5.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 EXF77980.1 - 2.5e-05 24.0 3.0 0.019 15.1 0.0 4.9 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EXF77980.1 - 5.4e-05 22.7 4.4 0.97 9.1 0.0 4.7 4 1 1 5 5 5 2 TPR repeat TPR_19 PF14559.1 EXF77980.1 - 6.4e-05 23.2 5.8 0.0036 17.5 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EXF77980.1 - 8e-05 22.1 1.6 0.0036 16.9 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EXF77980.1 - 0.00025 20.9 2.8 3.4 7.6 0.0 5.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EXF77980.1 - 0.0034 17.0 0.7 3 7.8 0.0 5.1 6 1 0 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 EXF77980.1 - 0.061 13.4 1.1 25 5.0 0.0 3.8 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EXF77980.1 - 0.094 13.2 3.1 7.5 7.2 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat RIX1 PF08167.7 EXF77981.1 - 1.3e-43 148.5 0.0 2.2e-43 147.7 0.0 1.4 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis WW PF00397.21 EXF77982.1 - 1.1e-06 28.3 2.6 2.5e-06 27.2 1.8 1.6 1 0 0 1 1 1 1 WW domain Glyco_hydro_16 PF00722.16 EXF77984.1 - 6.6e-10 38.5 3.1 1e-09 37.9 2.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PTPLA PF04387.9 EXF77985.1 - 3.2e-53 179.5 15.9 5e-53 178.8 11.1 1.3 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA Abhydrolase_5 PF12695.2 EXF77986.1 - 3e-08 33.5 1.8 1.4e-05 24.9 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF676 PF05057.9 EXF77986.1 - 0.00013 21.3 0.0 0.00022 20.6 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EXF77986.1 - 0.00071 19.2 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EXF77986.1 - 0.003 17.4 2.7 0.011 15.6 1.9 2.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EXF77986.1 - 0.038 13.5 0.5 0.11 12.0 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.15 EXF77986.1 - 0.041 14.1 0.0 0.089 12.9 0.0 1.5 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_2 PF02230.11 EXF77986.1 - 0.087 12.2 0.1 0.63 9.4 0.0 2.3 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase HET PF06985.6 EXF77987.1 - 2e-20 73.3 7.9 1.6e-17 63.9 1.1 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DIOX_N PF14226.1 EXF77988.1 - 3.1e-22 79.2 0.0 5.7e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EXF77988.1 - 3.8e-19 68.8 0.0 5.9e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Amidohydro_2 PF04909.9 EXF77989.1 - 2.3e-43 148.7 0.1 2.8e-43 148.4 0.1 1.2 1 0 0 1 1 1 1 Amidohydrolase TatD_DNase PF01026.16 EXF77989.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 TatD related DNase TruD PF01142.13 EXF77990.1 - 4.3e-51 173.7 0.0 3.8e-50 170.6 0.0 2.2 2 0 0 2 2 2 1 tRNA pseudouridine synthase D (TruD) Pkinase PF00069.20 EXF77991.1 - 2.9e-60 203.6 0.0 3.5e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF77991.1 - 5.8e-35 120.6 0.0 7.8e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF77991.1 - 4.5e-07 29.1 0.0 6.4e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like DEAD PF00270.24 EXF77992.1 - 2.5e-40 137.7 0.0 7e-40 136.2 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF77992.1 - 1.2e-25 89.1 0.1 4.5e-25 87.3 0.1 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EXF77992.1 - 1.6e-05 23.8 0.0 2.4e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EXF77992.1 - 0.0041 16.9 0.0 0.014 15.2 0.0 1.8 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PBP1_TM PF14812.1 EXF77992.1 - 0.35 11.1 3.3 0.86 9.9 2.3 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Kelch_5 PF13854.1 EXF77996.1 - 1.5e-12 47.1 11.6 7.5e-11 41.7 0.0 5.2 5 0 0 5 5 5 2 Kelch motif SKG6 PF08693.5 EXF77996.1 - 6.7e-05 22.1 0.0 0.00012 21.2 0.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_3 PF13415.1 EXF77996.1 - 0.0004 20.4 11.8 0.0098 16.0 0.1 5.1 6 0 0 6 6 6 2 Galactose oxidase, central domain Kelch_2 PF07646.10 EXF77996.1 - 0.006 16.3 4.4 0.79 9.5 0.0 5.0 6 0 0 6 6 6 1 Kelch motif Serglycin PF04360.7 EXF77996.1 - 0.083 12.6 4.1 0.19 11.4 2.9 1.6 1 0 0 1 1 1 0 Serglycin Syndecan PF01034.15 EXF77996.1 - 0.13 11.9 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Plasmodium_Vir PF05795.6 EXF77996.1 - 0.17 11.0 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein CD99L2 PF12301.3 EXF77996.1 - 0.24 11.0 2.7 0.53 9.9 1.9 1.6 1 0 0 1 1 1 0 CD99 antigen like protein 2 Beta-APP PF03494.8 EXF77996.1 - 0.57 9.6 2.9 1.3 8.5 2.0 1.6 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Kelch_1 PF01344.20 EXF77996.1 - 4.4 6.9 6.8 0.64 9.6 0.2 3.1 4 0 0 4 4 4 0 Kelch motif GCV_T PF01571.16 EXF77997.1 - 5.6e-14 52.0 0.0 1.1e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EXF77997.1 - 0.0099 15.8 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DnaJ PF00226.26 EXF77998.1 - 8.9e-13 47.7 3.3 4.1e-12 45.6 0.6 2.8 2 0 0 2 2 2 1 DnaJ domain DUF4613 PF15390.1 EXF77998.1 - 0.026 12.7 4.6 0.032 12.4 3.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) SAD_SRA PF02182.12 EXF77999.1 - 3.9e-06 26.2 0.2 6.7e-06 25.4 0.1 1.4 1 0 0 1 1 1 1 SAD/SRA domain Catalase PF00199.14 EXF78000.1 - 8.2e-155 515.2 0.1 1.1e-154 514.8 0.1 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EXF78000.1 - 1.9e-20 72.4 0.0 3.4e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Catalase-related immune-responsive Cytadhesin_P30 PF07271.6 EXF78000.1 - 0.38 9.9 2.5 0.64 9.2 1.7 1.3 1 0 0 1 1 1 0 Cytadhesin P30/P32 Ribosomal_S8 PF00410.14 EXF78001.1 - 1.2e-25 89.8 0.0 1.6e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Ribosomal_L7Ae PF01248.21 EXF78002.1 - 1.3e-28 98.3 1.0 1.6e-28 98.0 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PucR PF07905.6 EXF78002.1 - 0.09 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Rotamase PF00639.16 EXF78003.1 - 3.2e-18 66.2 0.1 3.2e-18 66.2 0.0 1.7 2 0 0 2 2 2 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EXF78003.1 - 1.2e-17 64.2 0.1 2.1e-17 63.4 0.1 1.4 1 1 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.1 EXF78003.1 - 5.1e-06 27.1 0.6 7.2e-06 26.6 0.1 1.5 1 1 1 2 2 2 1 PPIC-type PPIASE domain DUF563 PF04577.9 EXF78004.1 - 1.5e-25 90.3 0.0 2.2e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Asp PF00026.18 EXF78005.1 - 0.0033 16.7 0.2 0.0098 15.1 0.0 1.9 2 1 0 2 2 2 1 Eukaryotic aspartyl protease VSP PF03302.8 EXF78005.1 - 0.022 13.4 1.8 0.036 12.7 1.2 1.3 1 0 0 1 1 1 0 Giardia variant-specific surface protein GST_N_3 PF13417.1 EXF78006.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EXF78006.1 - 2.6e-13 49.7 0.1 8.8e-13 48.0 0.1 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EXF78006.1 - 2.1e-12 47.0 0.0 5.2e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EXF78006.1 - 5.4e-11 42.3 0.0 1.1e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EXF78006.1 - 2.1e-08 33.9 0.7 2.1e-08 33.9 0.5 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EXF78006.1 - 4.2e-07 30.3 0.5 6.7e-07 29.7 0.4 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NADH_u_ox_C PF12853.2 EXF78006.1 - 0.063 12.9 0.4 0.13 12.0 0.0 1.7 2 0 0 2 2 2 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit MFS_1 PF07690.11 EXF78007.1 - 5.4e-22 77.9 43.4 5.4e-22 77.9 30.1 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily MMPL PF03176.10 EXF78007.1 - 0.008 14.9 1.4 0.021 13.5 0.9 1.6 1 0 0 1 1 1 1 MMPL family HAD PF12710.2 EXF78008.1 - 3.7e-20 72.9 0.1 1.2e-19 71.2 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EXF78008.1 - 9e-20 70.6 0.0 1.6e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EXF78008.1 - 1.8e-15 57.9 1.7 2.1e-14 54.4 1.2 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EXF78008.1 - 2.8e-12 46.4 0.0 7.1e-12 45.1 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EXF78008.1 - 0.00099 18.7 0.6 0.013 15.0 0.2 2.4 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EXF78008.1 - 0.015 15.5 0.0 0.046 13.9 0.0 1.8 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Cript PF10235.4 EXF78009.1 - 4.2e-27 94.3 10.6 6.7e-27 93.6 7.3 1.3 1 0 0 1 1 1 1 Microtubule-associated protein CRIPT DUF2039 PF10217.4 EXF78009.1 - 0.00046 20.1 6.0 0.00046 20.1 4.2 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) DZR PF12773.2 EXF78009.1 - 0.024 14.4 13.9 0.043 13.6 2.7 2.9 2 1 1 3 3 3 0 Double zinc ribbon Ribosomal_L32p PF01783.18 EXF78009.1 - 0.24 11.5 9.7 0.12 12.5 3.9 2.5 2 1 1 3 3 3 0 Ribosomal L32p protein family zf-ribbon_3 PF13248.1 EXF78009.1 - 0.31 10.3 11.1 0.67 9.2 0.9 3.1 3 0 0 3 3 3 0 zinc-ribbon domain zinc_ribbon_2 PF13240.1 EXF78009.1 - 0.58 9.7 13.0 9.5 5.8 4.8 3.2 2 1 0 2 2 2 0 zinc-ribbon domain C6_DPF PF10170.4 EXF78009.1 - 1.1 9.3 6.0 1.8 8.6 3.9 1.5 1 1 0 1 1 1 0 Cysteine-rich domain DUF1272 PF06906.6 EXF78009.1 - 1.8 8.4 7.7 0.25 11.2 2.4 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1272) Zn_Tnp_IS91 PF14319.1 EXF78009.1 - 2.3 7.7 8.6 1.3 8.5 3.8 1.9 2 0 0 2 2 2 0 Transposase zinc-binding domain zf-RING_5 PF14634.1 EXF78009.1 - 3.9 7.2 12.6 17 5.2 6.4 2.9 2 1 0 2 2 2 0 zinc-RING finger domain Abhydrolase_6 PF12697.2 EXF78010.1 - 1.7e-31 109.8 0.0 3.1e-31 109.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF78010.1 - 3.5e-20 72.5 0.0 8.1e-18 64.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF78010.1 - 2.4e-13 50.0 0.0 6.7e-13 48.6 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EXF78010.1 - 4.9e-05 23.1 0.0 8.4e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_2 PF02230.11 EXF78010.1 - 0.027 13.9 0.0 0.087 12.2 0.0 1.9 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.5 EXF78010.1 - 0.061 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Pinin_SDK_memA PF04696.8 EXF78011.1 - 7.3e-25 87.0 15.0 7.3e-25 87.0 10.4 2.8 2 0 0 2 2 2 1 pinin/SDK/memA/ protein conserved region Pex26 PF07163.7 EXF78011.1 - 0.046 12.6 1.3 0.11 11.3 0.9 1.6 1 0 0 1 1 1 0 Pex26 protein OmpH PF03938.9 EXF78011.1 - 5.5 6.9 24.0 1.5 8.7 1.8 3.1 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) SAPS PF04499.10 EXF78011.1 - 8.2 4.9 15.1 0.16 10.5 1.0 2.2 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein PHF5 PF03660.9 EXF78012.1 - 1.6e-51 172.8 10.6 1.9e-51 172.6 7.3 1.0 1 0 0 1 1 1 1 PHF5-like protein DZR PF12773.2 EXF78012.1 - 1.1 9.1 15.8 19 5.1 10.1 2.8 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.1 EXF78012.1 - 1.4 8.7 15.7 3 7.6 0.5 3.1 3 1 0 3 3 3 0 Prokaryotic RING finger family 1 PolC_DP2 PF03833.8 EXF78012.1 - 4 4.9 5.7 3.9 5.0 4.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 PHD PF00628.24 EXF78012.1 - 7.2 6.3 15.4 0.21 11.2 4.5 2.5 1 1 1 2 2 2 0 PHD-finger CAF1 PF04857.15 EXF78013.1 - 1.6e-42 145.6 0.0 2.1e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.15 EXF78013.1 - 0.0059 16.1 0.0 0.075 12.5 0.0 2.2 2 0 0 2 2 2 1 3'-5' exonuclease MRP-L46 PF11788.3 EXF78014.1 - 3.6e-22 79.1 0.0 5.9e-22 78.4 0.0 1.4 1 0 0 1 1 1 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EXF78014.1 - 0.0022 17.6 0.1 0.0043 16.6 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain RPA PF10134.4 EXF78014.1 - 0.13 11.5 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Replication initiator protein A zf-RING_2 PF13639.1 EXF78015.1 - 2.5e-10 39.9 20.6 8.8e-10 38.2 0.5 3.8 3 1 1 4 4 4 1 Ring finger domain zf-rbx1 PF12678.2 EXF78015.1 - 4.8e-10 39.4 15.7 4.7e-08 33.0 3.8 3.2 2 1 0 2 2 2 2 RING-H2 zinc finger PHD PF00628.24 EXF78015.1 - 1.4e-09 37.4 7.9 1.4e-09 37.4 5.5 2.6 2 0 0 2 2 2 1 PHD-finger zf-C3HC4_3 PF13920.1 EXF78015.1 - 8.1e-07 28.6 0.5 8.1e-07 28.6 0.3 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.1 EXF78015.1 - 1.2e-06 27.7 3.1 1.2e-06 27.7 2.1 2.3 2 0 0 2 2 2 1 PHD-finger zf-RING_5 PF14634.1 EXF78015.1 - 1.9e-05 24.2 0.5 1.9e-05 24.2 0.3 3.2 3 1 1 4 4 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EXF78015.1 - 4.8e-05 23.2 0.9 4.8e-05 23.2 0.6 3.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EXF78015.1 - 6.4e-05 22.5 4.0 6.4e-05 22.5 2.8 3.4 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EXF78015.1 - 0.0001 21.7 3.0 0.00059 19.3 0.2 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 EXF78015.1 - 0.00046 19.9 8.6 0.012 15.4 0.1 2.6 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 11 RING-H2 finger zf-PHD-like PF15446.1 EXF78015.1 - 0.0016 17.7 1.0 0.0016 17.7 0.7 2.3 2 0 0 2 2 2 1 PHD/FYVE-zinc-finger like domain Rtf2 PF04641.7 EXF78015.1 - 0.0079 15.4 0.6 0.077 12.1 0.0 2.3 2 0 0 2 2 2 1 Rtf2 RING-finger Serglycin PF04360.7 EXF78015.1 - 0.02 14.6 2.8 0.042 13.5 1.9 1.5 1 0 0 1 1 1 0 Serglycin zf-P11 PF03854.9 EXF78015.1 - 0.036 13.5 0.6 0.036 13.5 0.4 2.1 2 0 0 2 2 2 0 P-11 zinc finger Prok-RING_1 PF14446.1 EXF78015.1 - 0.093 12.4 8.4 0.22 11.2 3.8 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_6 PF14835.1 EXF78015.1 - 0.1 12.4 0.2 0.1 12.4 0.2 2.0 2 0 0 2 2 1 0 zf-RING of BARD1-type protein DUF4463 PF14703.1 EXF78015.1 - 1.2 9.6 5.8 1.1 9.8 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) DZR PF12773.2 EXF78015.1 - 4.4 7.1 11.5 6.2e+02 0.3 8.0 2.8 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_3 PF14369.1 EXF78015.1 - 5.1 7.1 11.5 22 5.1 0.2 3.8 3 0 0 3 3 3 0 zinc-finger Rad50_zn_hook PF04423.9 EXF78015.1 - 9.4 5.7 7.3 1 8.9 0.1 2.6 3 0 0 3 3 3 0 Rad50 zinc hook motif Ribosomal_L37ae PF01780.14 EXF78016.1 - 3.1e-38 129.5 6.2 3.9e-38 129.1 4.3 1.1 1 0 0 1 1 1 1 Ribosomal L37ae protein family A2L_zn_ribbon PF08792.5 EXF78016.1 - 0.036 13.5 3.4 0.64 9.5 0.0 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 EXF78016.1 - 0.04 13.7 3.3 0.064 13.0 2.3 1.3 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Saccharop_dh PF03435.13 EXF78017.1 - 9.9e-18 64.2 0.0 1.7e-16 60.2 0.0 2.0 2 0 0 2 2 2 2 Saccharopine dehydrogenase DUF155 PF02582.9 EXF78018.1 - 1.2e-56 191.4 0.3 1.8e-56 190.8 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 HMG_box PF00505.14 EXF78019.1 - 1.1e-12 48.0 2.0 2.4e-12 46.9 1.4 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EXF78019.1 - 2.2e-06 27.9 3.3 2.2e-06 27.9 2.3 2.3 2 1 1 3 3 3 1 HMG-box domain KfrA_N PF11740.3 EXF78019.1 - 0.017 15.5 10.8 0.21 12.0 3.2 2.6 2 0 0 2 2 2 0 Plasmid replication region DNA-binding N-term DUF972 PF06156.8 EXF78019.1 - 0.26 11.6 0.1 0.26 11.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) SlyX PF04102.7 EXF78019.1 - 0.97 9.8 6.6 2.2 8.7 0.1 3.2 2 1 1 3 3 3 0 SlyX Atg14 PF10186.4 EXF78019.1 - 5.7 5.7 12.6 0.24 10.2 2.3 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Cpn60_TCP1 PF00118.19 EXF78020.1 - 3.7e-139 464.4 2.1 4.2e-139 464.2 1.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family PP1_inhibitor PF05361.7 EXF78020.1 - 0.017 14.8 0.2 0.076 12.7 0.2 2.1 2 1 0 2 2 2 0 PKC-activated protein phosphatase-1 inhibitor EAL PF00563.15 EXF78020.1 - 0.032 13.6 0.0 0.076 12.4 0.0 1.5 1 0 0 1 1 1 0 EAL domain FAD_binding_4 PF01565.18 EXF78021.1 - 2.6e-15 56.1 0.1 3.9e-15 55.5 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF78021.1 - 5e-05 23.1 0.2 0.00011 22.0 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.20 EXF78022.1 - 9.7e-17 61.3 0.0 1.4e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF78022.1 - 4.3e-08 33.2 0.0 6.2e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SSP160 PF06933.6 EXF78022.1 - 0.0019 16.2 0.2 0.0026 15.8 0.2 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 KR PF08659.5 EXF78022.1 - 0.0039 16.8 0.0 0.012 15.2 0.0 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF78022.1 - 0.019 14.3 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Sugar_tr PF00083.19 EXF78023.1 - 1.1e-70 238.4 23.2 1.3e-70 238.2 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF78023.1 - 1.1e-25 90.1 47.7 3.6e-19 68.7 18.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 EXF78024.1 - 3.8e-24 84.9 0.4 6e-24 84.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF78024.1 - 9e-07 28.7 5.2 2.9e-06 27.0 3.6 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_fiss_reg PF05308.6 EXF78024.1 - 3.3 7.0 6.4 7.9 5.7 4.4 1.6 1 0 0 1 1 1 0 Mitochondrial fission regulator AMP-binding PF00501.23 EXF78025.1 - 7.6e-84 281.5 0.0 1.1e-83 280.9 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme adh_short PF00106.20 EXF78026.1 - 1.7e-06 28.0 0.0 2.4e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Cyclase PF04199.8 EXF78027.1 - 1.1e-13 51.2 0.0 3e-13 49.8 0.0 1.7 1 1 1 2 2 2 1 Putative cyclase F-box-like PF12937.2 EXF78028.1 - 0.002 17.8 0.3 0.0043 16.7 0.2 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EXF78028.1 - 0.0054 16.3 0.2 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 F-box domain HNH_2 PF13391.1 EXF78029.1 - 1.4e-05 24.8 0.0 3.5e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease Pol_alpha_B_N PF08418.5 EXF78029.1 - 0.0018 17.8 0.9 0.0027 17.2 0.6 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DUF3328 PF11807.3 EXF78030.1 - 5.2e-31 108.0 0.2 1.2e-30 106.8 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EXF78032.1 - 3.2e-22 79.2 0.6 4.2e-22 78.9 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) 2OG-FeII_Oxy PF03171.15 EXF78033.1 - 0.0081 16.4 0.0 0.024 14.9 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PH_10 PF15411.1 EXF78035.1 - 2.4e-26 92.1 0.3 4e-26 91.4 0.2 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain VWA_3 PF13768.1 EXF78035.1 - 9.3e-10 38.3 0.0 2.4e-09 37.0 0.0 1.7 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EXF78035.1 - 2.3e-07 30.7 0.1 4.9e-07 29.6 0.1 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 EXF78035.1 - 3.5e-07 29.9 6.0 6.2e-07 29.1 4.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EXF78035.1 - 0.003 17.2 5.2 0.005 16.5 3.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EXF78035.1 - 0.012 15.7 1.0 0.023 14.7 0.7 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger PH PF00169.24 EXF78035.1 - 0.071 13.3 0.1 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 PH domain zf-C3HC4 PF00097.20 EXF78035.1 - 0.096 12.3 5.4 0.18 11.5 3.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EXF78035.1 - 0.11 12.6 5.2 0.18 11.8 3.6 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1147 PF06615.6 EXF78035.1 - 0.12 12.1 0.4 0.34 10.7 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1147) zf-RING-like PF08746.6 EXF78035.1 - 0.39 10.7 4.5 0.72 9.9 3.1 1.4 1 0 0 1 1 1 0 RING-like domain MFS_1 PF07690.11 EXF78039.1 - 3e-30 105.1 26.6 5.6e-30 104.2 18.0 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily PLAC8 PF04749.12 EXF78039.1 - 0.069 13.7 0.1 0.26 11.8 0.0 1.9 1 0 0 1 1 1 0 PLAC8 family U3_snoRNA_assoc PF08297.6 EXF78040.1 - 2.4e-08 34.0 0.9 2.4e-08 34.0 0.6 3.8 3 1 0 3 3 3 1 U3 snoRNA associated TPR_8 PF13181.1 EXF78041.1 - 0.0013 18.3 0.4 0.051 13.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EXF78041.1 - 0.0036 17.0 5.4 0.055 13.4 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.4 EXF78041.1 - 0.0037 17.1 1.6 0.013 15.4 0.4 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EXF78041.1 - 0.0061 16.1 0.6 0.016 14.8 0.4 1.8 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 EXF78041.1 - 0.0073 15.8 3.1 1.2 8.8 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EXF78041.1 - 0.013 15.3 1.9 0.036 13.9 1.3 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat HRXXH PF13933.1 EXF78041.1 - 0.13 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative peptidase family Glyco_hydro_35 PF01301.14 EXF78042.1 - 6.1e-78 262.3 3.0 9.4e-78 261.7 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 EXF78042.1 - 9.2e-54 180.4 6.9 2.2e-27 95.5 1.8 3.3 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 EXF78042.1 - 7.8e-48 162.2 1.5 1.3e-47 161.4 1.1 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 EXF78042.1 - 1.9e-23 81.6 0.2 2.4e-22 78.1 0.0 2.6 3 0 0 3 3 3 1 Beta-galactosidase, domain 3 Cellulase PF00150.13 EXF78042.1 - 6.8e-05 22.1 0.2 0.00056 19.1 0.0 2.5 2 1 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) Peptidase_M16_C PF05193.16 EXF78044.1 - 9.4e-19 67.7 0.0 5.7e-14 52.1 0.0 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EXF78044.1 - 9.2e-06 25.4 0.1 6e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) M16C_assoc PF08367.6 EXF78044.1 - 0.25 10.1 2.8 13 4.5 0.0 2.4 2 0 0 2 2 2 0 Peptidase M16C associated Sporozoite_P67 PF05642.6 EXF78044.1 - 0.34 8.7 2.9 0.49 8.1 2.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Nucleoplasmin PF03066.10 EXF78044.1 - 3.7 7.0 10.8 7.3 6.0 7.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin Zw10 PF06248.8 EXF78045.1 - 1.9e-11 42.8 3.3 7e-10 37.6 0.7 2.4 2 1 0 2 2 2 2 Centromere/kinetochore Zw10 Dsl1_C PF11989.3 EXF78045.1 - 0.024 13.7 0.0 0.15 11.2 0.0 2.2 2 0 0 2 2 2 0 Retrograde transport protein Dsl1 C terminal CorA PF01544.13 EXF78045.1 - 0.037 13.0 1.8 0.075 12.0 1.3 1.4 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Nop14 PF04147.7 EXF78045.1 - 0.062 11.2 13.7 0.092 10.6 9.5 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EXF78045.1 - 9.5 4.5 15.6 16 3.8 10.8 1.2 1 0 0 1 1 1 0 Daxx Family End3 PF12761.2 EXF78047.1 - 0.00029 20.5 0.4 0.00049 19.8 0.3 1.4 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 FlxA PF14282.1 EXF78047.1 - 0.047 13.6 0.2 0.047 13.6 0.1 2.4 3 0 0 3 3 3 0 FlxA-like protein TMF_DNA_bd PF12329.3 EXF78047.1 - 0.058 13.2 3.9 2.9 7.7 1.4 3.0 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 EXF78047.1 - 0.2 11.5 5.6 0.47 10.3 3.9 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.1 EXF78047.1 - 0.33 10.1 3.7 0.55 9.3 2.6 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 EXF78047.1 - 0.39 8.5 1.0 0.5 8.1 0.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Tmemb_cc2 PF10267.4 EXF78047.1 - 0.55 8.7 6.7 1 7.9 4.6 1.4 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein AKAP7_NLS PF10469.4 EXF78048.1 - 1.3e-34 119.7 0.0 1.6e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain Hpt PF01627.18 EXF78049.1 - 2.2e-10 40.4 0.0 2.7e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Hpt domain Daxx PF03344.10 EXF78050.1 - 0.084 11.3 18.6 0.1 11.0 12.9 1.1 1 0 0 1 1 1 0 Daxx Family Ycf1 PF05758.7 EXF78050.1 - 7 4.2 12.5 8.9 3.8 8.7 1.2 1 0 0 1 1 1 0 Ycf1 Nop25 PF09805.4 EXF78050.1 - 8.5 6.4 26.2 0.83 9.7 13.0 2.2 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Metallophos PF00149.23 EXF78052.1 - 3.1e-37 127.9 0.5 7.4e-29 100.5 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase DUF3584 PF12128.3 EXF78054.1 - 0.065 10.5 4.1 0.086 10.1 2.8 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) bZIP_1 PF00170.16 EXF78054.1 - 1.2 9.0 12.2 3.3 7.7 8.4 1.7 1 1 0 1 1 1 0 bZIP transcription factor PE_PPE_C PF12484.3 EXF78055.1 - 0.1 13.5 0.1 0.12 13.3 0.0 1.4 1 1 0 1 1 1 0 Polymorphic PE/PPE proteins C terminal AFG1_ATPase PF03969.11 EXF78056.1 - 4.1e-95 318.6 0.0 1.9e-90 303.2 0.0 2.1 2 0 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EXF78056.1 - 1.3e-05 25.3 0.4 0.052 13.5 0.0 3.0 2 1 1 3 3 3 2 AAA ATPase domain Bac_DnaA PF00308.13 EXF78056.1 - 0.00015 21.4 0.1 0.34 10.5 0.0 2.6 2 1 0 2 2 2 2 Bacterial dnaA protein Sigma54_activ_2 PF14532.1 EXF78056.1 - 0.00046 20.2 0.0 0.014 15.4 0.0 2.6 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.1 EXF78056.1 - 0.0024 17.9 0.0 0.018 15.2 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EXF78056.1 - 0.005 16.7 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EXF78056.1 - 0.0074 16.0 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ROS_MUCR PF05443.6 EXF78056.1 - 0.016 14.9 0.1 0.096 12.4 0.0 2.1 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein AAA PF00004.24 EXF78056.1 - 0.046 13.9 0.0 0.13 12.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EXF78056.1 - 0.1 12.7 0.0 0.36 11.0 0.0 2.1 1 1 0 1 1 1 0 RNA helicase NACHT PF05729.7 EXF78056.1 - 0.11 12.1 0.0 0.29 10.7 0.0 1.8 1 1 0 1 1 1 0 NACHT domain DUF1295 PF06966.7 EXF78057.1 - 1e-15 57.6 0.0 1.4e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.12 EXF78057.1 - 5.4e-07 28.4 0.2 8.4e-07 27.8 0.1 1.3 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Permease PF02405.11 EXF78057.1 - 0.0018 17.7 0.4 0.0098 15.3 0.0 2.1 1 1 1 2 2 2 1 Permease Steroid_dh PF02544.11 EXF78057.1 - 0.0091 15.7 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Peptidase_M28 PF04389.12 EXF78058.1 - 2.2e-25 89.3 0.1 4.7e-25 88.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EXF78058.1 - 1.7e-05 24.4 0.1 7.4e-05 22.3 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 DSPc PF00782.15 EXF78059.1 - 5.1e-09 35.8 0.0 3.4e-07 29.9 0.0 2.2 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.7 EXF78059.1 - 0.1 11.4 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Initiator tRNA phosphoribosyl transferase PA26 PF04636.8 EXF78060.1 - 2.2 6.8 4.1 4.1 5.9 2.8 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) End3 PF12761.2 EXF78061.1 - 2.4e-71 239.4 0.2 3.2e-71 239.0 0.1 1.2 1 0 0 1 1 1 1 Actin cytoskeleton-regulatory complex protein END3 EF-hand_4 PF12763.2 EXF78061.1 - 4.9e-48 161.1 0.0 2.8e-47 158.7 0.0 2.0 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EXF78061.1 - 6.4e-07 28.2 0.2 1.8e-06 26.8 0.1 1.8 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.1 EXF78061.1 - 6.9e-07 28.7 0.1 1.3e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.1 EXF78061.1 - 0.00013 22.0 0.0 0.00046 20.2 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EXF78061.1 - 0.00044 19.8 0.9 0.0028 17.4 0.1 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_5 PF13202.1 EXF78061.1 - 0.01 15.1 2.4 0.014 14.7 0.1 2.4 2 0 0 2 2 2 0 EF hand Bacillus_HBL PF05791.6 EXF78061.1 - 0.043 13.1 1.2 0.37 10.1 0.1 2.3 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) MDMPI_N PF11716.3 EXF78061.1 - 0.084 13.2 0.2 0.38 11.1 0.0 2.0 2 0 0 2 2 2 0 Mycothiol maleylpyruvate isomerase N-terminal domain CENP-Q PF13094.1 EXF78061.1 - 0.33 10.9 4.6 1.4 8.9 0.8 2.8 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 EXF78061.1 - 0.6 9.6 2.9 3.6 7.1 2.0 2.0 1 1 0 1 1 1 0 IncA protein Pyr_redox_2 PF07992.9 EXF78062.1 - 2.5e-19 69.9 0.0 4.8e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF78062.1 - 2.8e-10 40.4 0.3 3.6e-09 36.9 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF78062.1 - 2.5e-05 24.4 0.1 0.19 11.7 0.0 3.1 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF78062.1 - 0.00029 19.8 0.1 0.0033 16.3 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EXF78062.1 - 0.00062 18.7 1.0 1.2 7.9 0.0 3.5 2 1 1 4 4 4 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EXF78062.1 - 0.001 18.8 0.0 3.2 7.5 0.0 3.7 3 1 1 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EXF78062.1 - 0.0014 17.5 0.0 1.1 8.0 0.0 2.4 2 0 0 2 2 2 2 Lycopene cyclase protein ACBP PF00887.14 EXF78063.1 - 3.8e-25 87.3 0.3 4.4e-25 87.1 0.2 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Imm38 PF15599.1 EXF78063.1 - 0.014 14.8 0.1 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Immunity protein 38 DUF1436 PF07262.6 EXF78063.1 - 0.13 11.7 0.3 0.53 9.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1436) Tyr-DNA_phospho PF06087.7 EXF78064.1 - 4.8e-132 440.7 0.0 5.6e-132 440.5 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EXF78064.1 - 0.00012 21.8 0.1 0.11 12.2 0.0 2.3 2 0 0 2 2 2 2 PLD-like domain Ank_2 PF12796.2 EXF78065.1 - 1.6e-31 108.4 0.0 7.3e-12 45.4 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EXF78065.1 - 2.3e-24 83.9 0.8 3e-08 33.0 0.0 6.8 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 EXF78065.1 - 1.1e-18 67.2 6.1 5.6e-07 29.8 0.0 6.4 4 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF78065.1 - 6.1e-18 64.4 2.7 5.4e-05 23.2 0.0 5.9 4 2 3 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF78065.1 - 4e-17 60.6 4.7 1.1e-05 25.1 0.0 7.9 8 0 0 8 8 8 3 Ankyrin repeat HA PF03457.9 EXF78065.1 - 0.038 14.0 1.2 0.12 12.5 0.1 2.2 2 0 0 2 2 2 0 Helicase associated domain DUF460 PF04312.8 EXF78065.1 - 0.064 12.7 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF460) Spc7 PF08317.6 EXF78065.1 - 0.22 10.1 3.0 0.32 9.5 0.3 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein Thioredoxin PF00085.15 EXF78066.1 - 3e-40 136.1 0.1 6.7e-24 83.5 0.0 3.4 3 1 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.1 EXF78066.1 - 5.9e-11 42.5 0.0 2.7e-05 24.0 0.0 3.9 3 1 1 4 4 4 2 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EXF78066.1 - 1.2e-07 31.9 0.2 0.0026 17.9 0.1 4.3 3 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EXF78066.1 - 1.8e-05 24.7 0.5 0.00077 19.5 0.0 3.2 3 0 0 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EXF78066.1 - 0.00023 21.1 0.5 0.0016 18.3 0.1 2.6 2 0 0 2 2 2 1 Thioredoxin-like HyaE PF07449.6 EXF78066.1 - 0.0018 18.1 0.0 6.4 6.7 0.0 3.8 4 0 0 4 4 4 1 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 EXF78066.1 - 0.012 15.4 1.0 0.52 10.1 0.0 3.8 4 1 0 4 4 4 0 Thioredoxin domain AhpC-TSA PF00578.16 EXF78066.1 - 0.041 13.5 0.5 0.27 10.8 0.0 2.6 3 0 0 3 3 3 0 AhpC/TSA family 7TM_GPCR_Srh PF10318.4 EXF78066.1 - 0.11 11.2 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh HHV6-IE PF03753.8 EXF78066.1 - 4.8 4.5 7.1 7 3.9 4.9 1.2 1 0 0 1 1 1 0 Human herpesvirus 6 immediate early protein PLDc_2 PF13091.1 EXF78067.1 - 5.2e-17 61.7 0.0 2e-05 24.3 0.0 4.2 3 1 0 3 3 3 3 PLD-like domain PLDc PF00614.17 EXF78067.1 - 1.3e-10 40.6 0.8 6e-05 22.7 0.0 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif NYD-SP28_assoc PF14775.1 EXF78067.1 - 0.14 11.8 0.1 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Sperm tail C-terminal domain Acetyltransf_1 PF00583.19 EXF78068.1 - 4.1e-09 36.3 0.0 6e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EXF78068.1 - 0.0003 20.4 0.0 0.00053 19.6 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EXF78068.1 - 0.00061 19.8 0.0 0.00069 19.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EXF78068.1 - 0.00089 19.3 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Pro_CA PF00484.14 EXF78069.1 - 1.1e-26 93.6 0.0 1.4e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase DNA_topoisoIV PF00521.15 EXF78070.1 - 1.5e-123 412.8 0.5 8.4e-123 410.3 0.0 2.1 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EXF78070.1 - 3.4e-33 114.2 2.8 8.7e-33 112.9 1.9 1.7 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.17 EXF78070.1 - 4.9e-12 45.7 0.0 3.1e-11 43.1 0.0 2.5 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EXF78070.1 - 2.4e-11 43.3 0.0 7.2e-11 41.7 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Reticulon PF02453.12 EXF78071.1 - 1.3e-38 132.2 1.1 1.8e-38 131.8 0.8 1.2 1 0 0 1 1 1 1 Reticulon RabGAP-TBC PF00566.13 EXF78072.1 - 2.9e-47 160.9 0.2 1e-46 159.1 0.0 2.0 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Fib_alpha PF08702.5 EXF78072.1 - 0.29 11.2 9.9 0.45 10.6 1.8 2.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF342 PF03961.8 EXF78072.1 - 1.2 7.4 7.3 0.73 8.1 1.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF342) APG6 PF04111.7 EXF78072.1 - 1.6 7.7 26.6 0.1 11.5 3.5 4.0 4 0 0 4 4 4 0 Autophagy protein Apg6 AAA_13 PF13166.1 EXF78072.1 - 1.8 6.8 14.6 12 4.2 10.1 2.2 1 1 0 1 1 1 0 AAA domain Acyl-CoA_dh_C PF12806.2 EXF78072.1 - 4.7 7.0 13.1 0.96 9.3 1.7 3.4 3 0 0 3 3 3 0 Acetyl-CoA dehydrogenase C-terminal like V_ATPase_I PF01496.14 EXF78072.1 - 4.7 4.9 7.5 0.92 7.2 1.5 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF3584 PF12128.3 EXF78072.1 - 5.3 4.2 27.5 0.29 8.4 7.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3584) Laminin_II PF06009.7 EXF78072.1 - 7.9 6.2 17.0 0.074 12.8 2.6 3.3 3 0 0 3 3 3 0 Laminin Domain II Lipase_GDSL PF00657.17 EXF78075.1 - 8.3e-15 55.2 0.3 1.4e-14 54.5 0.2 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EXF78075.1 - 0.00071 19.7 5.1 0.0027 17.8 3.5 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Aminotran_1_2 PF00155.16 EXF78076.1 - 9.4e-66 222.2 0.0 1.1e-65 221.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EXF78076.1 - 0.11 10.7 0.0 0.14 10.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Glyco_hydro_76 PF03663.9 EXF78077.1 - 1.2e-119 400.0 9.5 1.4e-119 399.7 6.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 PMT PF02366.13 EXF78079.1 - 0.015 14.6 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Dolichyl-phosphate-mannose-protein mannosyltransferase MscL PF01741.13 EXF78080.1 - 8.5e-17 61.5 0.9 1.7e-16 60.5 0.6 1.5 1 1 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL zf-BED PF02892.10 EXF78080.1 - 0.00099 18.8 2.4 0.0016 18.1 1.6 1.4 1 0 0 1 1 1 1 BED zinc finger DUF3043 PF11241.3 EXF78080.1 - 0.037 13.6 0.0 0.065 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DZR PF12773.2 EXF78080.1 - 0.098 12.4 1.2 0.16 11.7 0.8 1.2 1 0 0 1 1 1 0 Double zinc ribbon C1_1 PF00130.17 EXF78080.1 - 0.12 12.1 2.7 0.19 11.4 1.8 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SUR7 PF06687.7 EXF78081.1 - 2.5e-30 105.6 1.2 2.9e-30 105.4 0.8 1.0 1 0 0 1 1 1 1 SUR7/PalI family Fig1 PF12351.3 EXF78081.1 - 4.6e-09 36.4 2.6 4.6e-09 36.4 1.8 1.8 2 0 0 2 2 2 1 Ca2+ regulator and membrane fusion protein Fig1 PMP22_Claudin PF00822.15 EXF78081.1 - 1.8 8.1 8.2 0.71 9.5 2.4 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family DUF3165 PF11364.3 EXF78081.1 - 6.7 6.9 7.5 15 5.7 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3165) ABC_tran PF00005.22 EXF78082.1 - 8.8e-46 155.6 0.0 5.1e-23 81.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EXF78082.1 - 2e-31 109.4 29.7 3.1e-24 85.8 6.0 3.0 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 EXF78082.1 - 1.3e-16 61.4 1.8 0.0016 18.5 0.0 4.3 2 2 1 4 4 4 4 AAA domain SMC_N PF02463.14 EXF78082.1 - 5.5e-10 38.8 0.0 0.0028 16.9 0.0 3.8 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EXF78082.1 - 2.1e-08 34.3 1.3 9.2e-05 22.5 0.5 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.1 EXF78082.1 - 2.4e-06 26.9 2.6 0.024 14.1 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.1 EXF78082.1 - 5.8e-06 26.2 0.2 0.0005 19.9 0.0 3.0 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 EXF78082.1 - 1.9e-05 24.1 0.7 0.071 12.5 0.1 2.9 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EXF78082.1 - 3.5e-05 23.7 0.3 0.093 12.6 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 EXF78082.1 - 4.2e-05 23.7 0.4 1.4 9.0 0.3 3.7 2 1 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EXF78082.1 - 0.00018 22.2 0.0 0.84 10.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EXF78082.1 - 0.00064 18.7 1.0 0.23 10.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein MobB PF03205.9 EXF78082.1 - 0.00075 19.2 0.4 0.72 9.5 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EXF78082.1 - 0.00094 18.4 0.2 0.53 9.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Zeta_toxin PF06414.7 EXF78082.1 - 0.0015 17.7 0.5 0.55 9.2 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin Miro PF08477.8 EXF78082.1 - 0.0015 19.0 0.1 0.42 11.1 0.2 2.5 2 0 0 2 2 2 1 Miro-like protein AAA_18 PF13238.1 EXF78082.1 - 0.0021 18.3 0.0 2.4 8.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.18 EXF78082.1 - 0.0021 17.8 3.3 0.38 10.5 0.1 2.4 2 0 0 2 2 2 2 Dynamin family AAA_23 PF13476.1 EXF78082.1 - 0.0021 18.4 0.2 2.5 8.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EXF78082.1 - 0.0021 17.9 0.5 2.2 8.2 0.0 3.2 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit UPF0079 PF02367.12 EXF78082.1 - 0.013 15.1 0.8 0.039 13.5 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_7 PF12775.2 EXF78082.1 - 0.065 12.2 0.1 0.23 10.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region D3 AAA_PrkA PF08298.6 EXF78082.1 - 0.069 11.8 0.0 1.6 7.3 0.0 2.2 2 0 0 2 2 2 0 PrkA AAA domain Mg_chelatase PF01078.16 EXF78082.1 - 0.083 12.0 0.2 2.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EXF78082.1 - 0.084 12.7 0.1 3.4 7.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 EXF78082.1 - 0.11 11.9 0.5 2.2 7.7 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 EXF78082.1 - 0.14 11.5 0.3 1.2 8.5 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family Guanylate_kin PF00625.16 EXF78082.1 - 0.25 10.7 0.8 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Guanylate kinase AAA_10 PF12846.2 EXF78082.1 - 0.26 10.6 6.5 8.7 5.6 0.0 3.7 4 0 0 4 4 4 0 AAA-like domain ABC_ATPase PF09818.4 EXF78082.1 - 0.37 9.3 1.5 1.1 7.7 0.1 2.4 2 0 0 2 2 2 0 Predicted ATPase of the ABC class Arch_ATPase PF01637.13 EXF78082.1 - 0.75 9.4 2.9 8.4 6.0 0.0 2.7 3 0 0 3 3 2 0 Archaeal ATPase DUF87 PF01935.12 EXF78082.1 - 3 7.5 4.9 0.71 9.6 0.8 1.8 2 0 0 2 2 1 0 Domain of unknown function DUF87 cobW PF02492.14 EXF78082.1 - 6.5 6.1 5.8 26 4.1 0.2 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NDT80_PhoG PF05224.7 EXF78084.1 - 1.3e-42 145.9 0.0 1.8e-42 145.4 0.0 1.2 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Spectrin PF00435.16 EXF78086.1 - 0.02 15.1 4.2 1.1 9.5 0.0 3.0 3 0 0 3 3 3 0 Spectrin repeat DUF2730 PF10805.3 EXF78086.1 - 0.03 14.0 1.1 0.34 10.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) TBPIP PF07106.8 EXF78086.1 - 0.067 12.7 4.0 3 7.3 0.1 3.1 3 0 0 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) HALZ PF02183.13 EXF78086.1 - 0.07 12.8 0.7 3.4 7.4 0.2 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper BLOC1_2 PF10046.4 EXF78086.1 - 0.082 13.0 4.9 0.76 9.9 0.1 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1955 PF09205.5 EXF78086.1 - 0.1 12.1 0.7 0.18 11.2 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1955) Sec8_exocyst PF04048.9 EXF78086.1 - 0.1 12.2 4.0 0.57 9.8 0.1 3.1 3 1 0 3 3 3 0 Sec8 exocyst complex component specific domain DUF1664 PF07889.7 EXF78086.1 - 0.27 11.0 8.7 3.8 7.3 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) NPV_P10 PF05531.7 EXF78086.1 - 0.33 11.2 7.4 1.6 8.9 1.0 3.2 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 EXF78086.1 - 0.37 9.4 6.3 8.8 4.8 0.0 3.0 3 0 0 3 3 3 0 Spc7 kinetochore protein DUF3740 PF12548.3 EXF78086.1 - 0.5 10.6 4.9 2.7 8.2 0.0 2.6 3 0 0 3 3 3 0 Sulfatase protein Med9 PF07544.8 EXF78086.1 - 0.67 9.7 6.0 1.7 8.4 0.2 3.3 3 1 1 4 4 4 0 RNA polymerase II transcription mediator complex subunit 9 Adeno_PIX PF03955.9 EXF78086.1 - 1.1 9.8 4.2 5.5 7.5 0.3 3.0 3 0 0 3 3 3 0 Adenovirus hexon-associated protein (IX) DUF948 PF06103.6 EXF78086.1 - 1.6 8.6 6.6 3.7 7.4 0.9 2.9 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Syntaxin-6_N PF09177.6 EXF78086.1 - 2.2 8.7 8.0 7.5 7.0 0.1 3.2 4 0 0 4 4 3 0 Syntaxin 6, N-terminal AAA_27 PF13514.1 EXF78086.1 - 3.2 5.3 6.3 1.3 6.6 0.3 2.6 3 0 0 3 3 3 0 AAA domain IncA PF04156.9 EXF78086.1 - 4.5 6.8 10.0 2.9 7.4 0.4 3.2 2 1 1 3 3 3 0 IncA protein Fib_alpha PF08702.5 EXF78086.1 - 4.8 7.2 13.1 1.8 8.6 0.1 3.4 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Baculo_PEP_C PF04513.7 EXF78086.1 - 9.3 6.0 9.3 4.5 7.0 0.1 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3328 PF11807.3 EXF78087.1 - 1.1e-21 77.5 6.2 3.5e-20 72.6 1.4 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF3328) DUF1648 PF07853.6 EXF78088.1 - 0.062 12.8 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1648) DUF3357 PF11837.3 EXF78088.1 - 0.089 12.6 0.8 0.49 10.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) UCR_6-4kD PF08997.5 EXF78088.1 - 0.1 12.3 0.0 54 3.6 0.0 3.2 3 0 0 3 3 3 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein DUF3328 PF11807.3 EXF78089.1 - 0.097 12.3 0.6 0.62 9.7 0.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) Ribosomal_S28e PF01200.13 EXF78090.1 - 0.0024 17.5 2.4 19 5.0 0.0 4.0 1 1 3 4 4 4 1 Ribosomal protein S28e DUF4031 PF13223.1 EXF78090.1 - 0.0038 17.3 0.5 7.7 6.7 0.1 3.5 1 1 3 4 4 4 2 Protein of unknown function (DUF4031) BHD_2 PF10404.4 EXF78090.1 - 0.014 15.7 3.1 16 5.9 0.0 3.9 1 1 3 4 4 4 0 Rad4 beta-hairpin domain 2 Dehydratase_LU PF02286.10 EXF78090.1 - 0.023 12.9 0.3 0.2 9.8 0.2 2.0 1 1 0 1 1 1 0 Dehydratase large subunit DUF4330 PF14221.1 EXF78090.1 - 0.027 14.3 0.2 0.052 13.4 0.1 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4330) Ank_2 PF12796.2 EXF78091.1 - 1.2e-62 208.2 14.1 7.9e-20 71.0 0.2 4.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EXF78091.1 - 1.9e-52 172.5 20.9 2.2e-07 30.3 0.1 8.1 8 0 0 8 8 8 8 Ankyrin repeat Ank_3 PF13606.1 EXF78091.1 - 8.2e-44 143.2 4.7 3.7e-05 23.5 0.0 8.1 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.1 EXF78091.1 - 3e-42 142.2 3.0 1.2e-09 38.4 0.0 5.5 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF78091.1 - 3e-31 106.7 16.1 3.1e-05 24.0 0.0 8.0 4 2 4 8 8 8 7 Ankyrin repeats (many copies) DAZAP2 PF11029.3 EXF78091.1 - 1 9.7 12.0 1.4 9.4 0.7 3.5 1 1 1 3 3 3 0 DAZ associated protein 2 (DAZAP2) DUF3328 PF11807.3 EXF78092.1 - 4.4e-23 82.1 0.0 5.6e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Aldedh PF00171.17 EXF78093.1 - 3.5e-154 513.5 0.2 4e-154 513.3 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EXF78093.1 - 0.00067 18.9 0.0 0.0062 15.8 0.0 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1487) Amidase PF01425.16 EXF78094.1 - 1.2e-94 317.7 0.0 1.3e-94 317.5 0.0 1.0 1 0 0 1 1 1 1 Amidase AA_permease_2 PF13520.1 EXF78095.1 - 2.6e-08 32.8 7.2 2.9e-08 32.6 5.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF78095.1 - 0.0002 19.8 4.3 0.00028 19.3 3.0 1.2 1 0 0 1 1 1 1 Amino acid permease DUF4112 PF13430.1 EXF78095.1 - 0.0067 16.3 0.1 0.014 15.3 0.1 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4112) Oxidored_FMN PF00724.15 EXF78096.1 - 7.9e-75 251.9 0.0 1.1e-74 251.4 0.0 1.2 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Fungal_trans PF04082.13 EXF78096.1 - 1.2e-11 44.0 0.1 2.4e-11 43.0 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain LamB_YcsF PF03746.11 EXF78097.1 - 4.4e-66 222.4 0.0 5.1e-66 222.2 0.0 1.0 1 0 0 1 1 1 1 LamB/YcsF family DUF1989 PF09347.5 EXF78098.1 - 3e-34 117.8 0.0 4e-34 117.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) NADHdh_A3 PF14987.1 EXF78098.1 - 0.019 14.8 0.3 0.049 13.5 0.2 1.6 1 0 0 1 1 1 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 Retro_M PF02813.9 EXF78098.1 - 0.12 12.5 0.0 0.31 11.2 0.0 1.6 1 0 0 1 1 1 0 Retroviral M domain Sugar_tr PF00083.19 EXF78099.1 - 9.6e-45 152.9 11.7 5.3e-32 110.9 1.2 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EXF78099.1 - 1.3e-17 63.5 18.7 4.7e-17 61.7 6.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EXF78099.1 - 0.0039 15.6 0.8 0.0039 15.6 0.5 2.9 2 2 0 2 2 2 1 MFS/sugar transport protein DUF2225 PF09986.4 EXF78099.1 - 0.21 11.0 0.1 0.38 10.1 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) p450 PF00067.17 EXF78100.1 - 3e-50 171.0 0.0 3.7e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Reticulon PF02453.12 EXF78100.1 - 0.1 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Reticulon p450 PF00067.17 EXF78101.1 - 1.6e-42 145.6 0.1 1.9e-42 145.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EXF78103.1 - 1.1e-14 54.0 1.8 1.8e-14 53.2 1.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF78103.1 - 5.5e-09 35.7 8.4 1e-08 34.9 5.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 EXF78104.1 - 6.1e-21 74.8 0.0 8.7e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF78104.1 - 3.5e-10 39.3 0.7 0.00033 19.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EXF78104.1 - 5.6e-05 23.4 0.4 0.0021 18.3 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF78104.1 - 0.019 14.9 0.3 0.072 13.1 0.1 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain ApbA PF02558.11 EXF78104.1 - 0.09 12.2 0.1 0.21 11.0 0.1 1.7 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA BNR PF02012.15 EXF78105.1 - 0.11 12.3 0.2 0.42 10.6 0.2 2.1 1 0 0 1 1 1 0 BNR/Asp-box repeat Homeobox_KN PF05920.6 EXF78106.1 - 2e-14 53.0 2.2 2.7e-14 52.5 0.6 2.0 2 0 0 2 2 2 1 Homeobox KN domain zf-C2H2_4 PF13894.1 EXF78106.1 - 1.3e-06 28.2 18.6 0.0098 16.1 2.9 4.1 3 0 0 3 3 3 3 C2H2-type zinc finger Homeobox PF00046.24 EXF78106.1 - 0.00033 20.2 0.1 0.00073 19.1 0.1 1.6 1 0 0 1 1 1 1 Homeobox domain HTH_Tnp_Tc5 PF03221.11 EXF78106.1 - 0.0018 18.0 0.3 0.052 13.3 0.0 3.1 3 0 0 3 3 3 1 Tc5 transposase DNA-binding domain zf-C2H2 PF00096.21 EXF78106.1 - 0.0037 17.5 22.0 0.015 15.5 2.6 4.2 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-met PF12874.2 EXF78106.1 - 0.66 10.2 7.3 8.5 6.7 0.2 4.2 4 0 0 4 4 4 0 Zinc-finger of C2H2 type MFS_1 PF07690.11 EXF78107.1 - 1.3e-11 43.7 23.2 1.6e-11 43.5 16.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_2 PF00891.13 EXF78109.1 - 1.3e-29 103.0 0.0 2.5e-29 102.1 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase DUF3662 PF12401.3 EXF78109.1 - 0.1 12.7 0.0 0.18 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2662) Abhydrolase_6 PF12697.2 EXF78110.1 - 3.6e-07 30.2 0.4 6.3e-07 29.5 0.3 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF1749 PF08538.5 EXF78110.1 - 0.082 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Abhydrolase_1 PF00561.15 EXF78110.1 - 0.11 12.0 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Filament_head PF04732.9 EXF78112.1 - 0.045 14.4 2.2 0.078 13.6 1.5 1.3 1 0 0 1 1 1 0 Intermediate filament head (DNA binding) region Defensin_2 PF01097.13 EXF78114.1 - 0.12 12.1 2.8 0.17 11.6 2.0 1.3 1 0 0 1 1 1 0 Arthropod defensin SNARE_assoc PF09335.6 EXF78115.1 - 5e-19 68.7 9.9 8.4e-18 64.7 6.4 2.4 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF1469 PF07332.6 EXF78115.1 - 0.0027 17.4 3.7 0.049 13.3 1.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF1469) CcmD PF04995.9 EXF78115.1 - 0.018 14.7 2.0 0.018 14.7 1.4 2.6 3 1 0 3 3 3 0 Heme exporter protein D (CcmD) DUF3671 PF12420.3 EXF78115.1 - 0.044 13.7 6.5 2.4 8.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function OPA3 PF07047.7 EXF78115.1 - 0.063 13.0 1.7 0.084 12.6 0.4 1.8 2 0 0 2 2 2 0 Optic atrophy 3 protein (OPA3) Cytadhesin_P30 PF07271.6 EXF78115.1 - 0.15 11.3 0.1 0.15 11.3 0.1 2.0 2 1 0 2 2 2 0 Cytadhesin P30/P32 DUF202 PF02656.10 EXF78115.1 - 0.51 10.5 7.9 2.9 8.1 0.0 3.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF2142 PF09913.4 EXF78115.1 - 2.2 6.8 10.6 0.05 12.2 0.9 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2142) CbiM PF01891.11 EXF78115.1 - 2.8 7.5 13.4 0.37 10.3 3.4 2.8 2 1 1 3 3 3 0 Cobalt uptake substrate-specific transmembrane region AhpC-TSA_2 PF13911.1 EXF78116.1 - 2.5e-18 66.0 0.0 1.1e-17 63.9 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EXF78116.1 - 0.0091 15.6 0.0 0.029 14.0 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family MIP-T3 PF10243.4 EXF78116.1 - 0.48 8.8 13.6 0.83 8.0 9.4 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 IBR PF01485.16 EXF78118.1 - 3.2e-07 30.1 9.8 5.5e-05 22.9 0.7 3.5 3 0 0 3 3 3 2 IBR domain DUF2321 PF10083.4 EXF78118.1 - 7 6.1 11.6 0.16 11.4 1.0 2.9 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) DUF2256 PF10013.4 EXF78118.1 - 8.8 6.1 10.9 4.2 7.1 0.1 3.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Peptidase_M24 PF00557.19 EXF78120.1 - 5e-47 160.1 0.1 6.5e-47 159.7 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Ribosomal_60s PF00428.14 EXF78120.1 - 0.2 12.0 4.9 0.54 10.6 3.4 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein PRELI PF04707.9 EXF78121.1 - 7.3e-39 132.8 0.0 8.7e-39 132.6 0.0 1.1 1 0 0 1 1 1 1 PRELI-like family GPW_gp25 PF04965.9 EXF78122.1 - 0.018 14.5 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Gene 25-like lysozyme E7 PF00527.13 EXF78122.1 - 0.049 13.7 0.0 0.097 12.8 0.0 1.4 2 0 0 2 2 2 0 E7 protein, Early protein AAA_17 PF13207.1 EXF78123.1 - 3.2e-06 27.9 2.3 8.3e-05 23.3 1.6 2.4 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EXF78123.1 - 9.6e-06 25.2 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EXF78123.1 - 1.3e-05 25.4 0.0 0.00044 20.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EXF78123.1 - 0.0012 17.8 0.1 0.012 14.5 0.0 2.0 2 0 0 2 2 2 1 Type II/IV secretion system protein Zeta_toxin PF06414.7 EXF78123.1 - 0.0015 17.6 0.1 0.0044 16.1 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin NB-ARC PF00931.17 EXF78123.1 - 0.0017 17.2 0.0 0.0025 16.7 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain Thymidylate_kin PF02223.12 EXF78123.1 - 0.0038 16.6 0.1 0.19 11.0 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase ArgK PF03308.11 EXF78123.1 - 0.013 14.2 0.0 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 ArgK protein RuvB_N PF05496.7 EXF78123.1 - 0.014 14.4 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EXF78123.1 - 0.019 14.8 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EXF78123.1 - 0.028 14.5 0.0 0.047 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EXF78123.1 - 0.068 12.8 0.2 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 NTPase AAA_19 PF13245.1 EXF78123.1 - 0.084 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain SKI PF01202.17 EXF78123.1 - 0.11 12.4 0.1 2.9 7.7 0.0 2.2 2 0 0 2 2 2 0 Shikimate kinase AAA PF00004.24 EXF78123.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EXF78123.1 - 0.14 11.6 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase cobW PF02492.14 EXF78123.1 - 0.16 11.4 0.3 0.23 10.8 0.2 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Tubulin PF00091.20 EXF78126.1 - 5.7e-72 242.0 0.0 8.3e-72 241.5 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EXF78126.1 - 1.5e-46 157.4 0.0 3.1e-46 156.5 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EXF78126.1 - 4.6e-08 33.1 0.0 9.3e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain PLDc PF00614.17 EXF78127.1 - 2.3e-16 59.0 1.2 6.5e-08 32.1 0.2 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EXF78127.1 - 3.1e-12 46.3 0.0 2.7e-07 30.3 0.0 2.6 2 0 0 2 2 2 2 PLD-like domain PX PF00787.19 EXF78127.1 - 1.2e-06 28.2 0.0 1.5e-05 24.7 0.0 2.8 2 1 0 2 2 2 1 PX domain COQ7 PF03232.8 EXF78128.1 - 8.3e-66 220.6 0.1 1e-65 220.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 EXF78128.1 - 0.004 17.4 0.0 0.0083 16.4 0.0 1.7 1 1 0 1 1 1 1 Rubrerythrin Vitellogenin_N PF01347.17 EXF78128.1 - 0.026 12.7 0.0 0.04 12.1 0.0 1.4 1 1 1 2 2 2 0 Lipoprotein amino terminal region Plus-3 PF03126.13 EXF78129.1 - 2.9e-30 104.4 0.0 6.5e-30 103.3 0.0 1.6 1 0 0 1 1 1 1 Plus-3 domain GDPD PF03009.12 EXF78130.1 - 1.5e-32 113.0 0.0 2.5e-32 112.3 0.0 1.4 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EXF78130.1 - 2.2e-05 24.4 0.9 2.2e-05 24.4 0.6 1.9 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Fungal_trans PF04082.13 EXF78131.1 - 2.5e-29 101.9 0.1 5.5e-29 100.8 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF78131.1 - 6e-10 38.8 11.5 1.1e-09 37.9 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Macoilin PF09726.4 EXF78131.1 - 0.82 7.8 7.4 1 7.5 0.1 2.1 2 0 0 2 2 2 0 Transmembrane protein SET PF00856.23 EXF78132.1 - 0.021 15.1 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 SET domain HEAT PF02985.17 EXF78134.1 - 8.1e-12 44.1 1.2 0.021 14.8 0.0 5.4 5 0 0 5 5 5 3 HEAT repeat Pkinase PF00069.20 EXF78134.1 - 2.4e-08 33.4 0.0 4.5e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT_EZ PF13513.1 EXF78134.1 - 2.9e-05 24.4 0.0 0.17 12.4 0.0 3.3 2 1 1 3 3 3 2 HEAT-like repeat Pkinase_Tyr PF07714.12 EXF78134.1 - 3.4e-05 23.0 0.0 6.3e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT_2 PF13646.1 EXF78134.1 - 4.2e-05 23.7 0.1 0.019 15.2 0.0 3.2 1 1 2 3 3 3 2 HEAT repeats Adaptin_N PF01602.15 EXF78134.1 - 0.097 10.9 0.0 0.29 9.4 0.0 1.4 1 1 0 1 1 1 0 Adaptin N terminal region Cnd1 PF12717.2 EXF78134.1 - 0.12 12.2 0.0 0.39 10.5 0.0 1.8 1 1 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 WD40 PF00400.27 EXF78135.1 - 4.5e-47 156.3 13.7 1.4e-11 43.8 0.0 7.4 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EXF78135.1 - 2.3e-06 26.0 2.2 0.26 9.3 0.0 4.5 4 1 0 5 5 5 2 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 EXF78135.1 - 0.0015 17.3 0.0 0.0021 16.9 0.0 1.2 1 0 0 1 1 1 1 Coatomer WD associated region DUF3312 PF11768.3 EXF78135.1 - 0.0015 16.8 0.0 0.0031 15.7 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3312) Nucleoporin_N PF08801.6 EXF78135.1 - 0.055 12.2 0.4 2.9 6.5 0.0 3.1 1 1 1 2 2 2 0 Nup133 N terminal like HPS3_N PF14761.1 EXF78135.1 - 0.064 12.6 0.0 0.4 10.0 0.0 2.1 2 1 1 3 3 3 0 Hermansky-Pudlak syndrome 3 SUKH_5 PF14567.1 EXF78135.1 - 0.14 11.6 0.3 6.6 6.1 0.1 3.0 2 1 1 3 3 3 0 SMI1-KNR4 cell-wall DUF3328 PF11807.3 EXF78136.1 - 1.4e-25 90.2 0.1 1.9e-25 89.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) ketoacyl-synt PF00109.21 EXF78137.1 - 7.6e-61 205.7 1.3 1.6e-60 204.7 0.9 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EXF78137.1 - 3.8e-45 154.6 1.0 6.1e-45 153.9 0.7 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EXF78137.1 - 8.1e-31 106.3 0.1 1.8e-30 105.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EXF78137.1 - 5.8e-24 85.5 0.0 3e-23 83.2 0.0 2.3 1 1 0 1 1 1 1 Thioesterase domain PS-DH PF14765.1 EXF78137.1 - 1.5e-21 76.8 0.2 2.6e-21 76.0 0.1 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 EXF78137.1 - 2.7e-10 40.3 0.6 6.1e-10 39.2 0.4 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Abhydrolase_5 PF12695.2 EXF78137.1 - 4.2e-09 36.2 0.6 0.00021 21.0 0.0 3.6 3 1 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF78137.1 - 1.7e-08 34.6 2.2 2.7e-06 27.4 0.1 3.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family Thiolase_N PF00108.18 EXF78137.1 - 0.0057 15.6 0.1 0.011 14.6 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain FHA PF00498.21 EXF78138.1 - 3.8e-10 39.7 0.0 7.6e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 FHA domain IFRD PF05004.8 EXF78139.1 - 4.4e-27 94.9 1.6 6.1e-27 94.5 1.1 1.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) HEAT_EZ PF13513.1 EXF78139.1 - 2.8e-05 24.4 4.2 0.00053 20.3 0.1 4.1 3 2 2 5 5 5 1 HEAT-like repeat HEAT_2 PF13646.1 EXF78139.1 - 0.00016 21.9 0.9 0.025 14.8 0.1 3.1 2 1 2 4 4 4 2 HEAT repeats HEAT PF02985.17 EXF78139.1 - 0.0019 18.1 0.1 0.17 12.0 0.0 3.0 2 0 0 2 2 2 1 HEAT repeat POX PF07526.6 EXF78139.1 - 0.12 12.6 3.3 6.3 7.0 1.2 2.7 2 1 0 2 2 2 0 Associated with HOX Rick_17kDa_Anti PF05433.10 EXF78140.1 - 5.8 6.6 37.3 0.97 9.1 4.6 4.4 4 0 0 4 4 4 0 Glycine zipper 2TM domain MMR_HSR1_C PF08438.5 EXF78141.1 - 6.6e-33 113.1 0.0 1.3e-32 112.2 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EXF78141.1 - 1.3e-08 34.8 0.0 3.6e-08 33.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF1551 PF07585.6 EXF78142.1 - 0.049 12.4 0.5 0.05 12.4 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1551) Pmp3 PF01679.12 EXF78143.1 - 4.9e-27 93.3 5.5 5.4e-27 93.2 3.8 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TM_helix PF05552.7 EXF78143.1 - 0.065 12.9 2.4 0.065 12.9 1.7 1.7 2 0 0 2 2 2 0 Conserved TM helix PIG-F PF06699.6 EXF78145.1 - 1.6e-55 188.0 4.5 2e-55 187.7 3.1 1.1 1 0 0 1 1 1 1 GPI biosynthesis protein family Pig-F PsbI PF02532.9 EXF78145.1 - 0.53 9.9 0.0 0.53 9.9 0.0 2.6 2 1 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) Bacteriocin_IIc PF10439.4 EXF78145.1 - 1.7 8.8 7.8 2.3 8.3 1.9 2.2 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Actin PF00022.14 EXF78147.1 - 4.7e-133 443.4 0.0 5.4e-133 443.2 0.0 1.0 1 0 0 1 1 1 1 Actin DUF3602 PF12223.3 EXF78148.1 - 1.4e-10 41.3 11.1 7e-06 26.3 2.1 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) HET PF06985.6 EXF78149.1 - 1.5e-23 83.4 0.0 3e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aconitase PF00330.15 EXF78150.1 - 3.4e-154 513.7 0.0 1.1e-153 512.0 0.0 1.7 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EXF78150.1 - 2.2e-38 131.3 0.0 3.6e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.8 EXF78150.1 - 0.006 15.1 0.0 0.01 14.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF521) COPIIcoated_ERV PF07970.7 EXF78151.1 - 1.5e-36 126.1 0.0 2e-36 125.6 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EXF78151.1 - 3e-21 75.1 0.0 5.3e-21 74.3 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Colicin_V PF02674.11 EXF78151.1 - 0.077 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Colicin V production protein ZZ PF00569.12 EXF78152.1 - 1.2e-17 63.1 60.5 5.3e-06 25.8 5.6 4.4 4 0 0 4 4 4 4 Zinc finger, ZZ type Btz PF09405.5 EXF78153.1 - 1.3e-27 96.3 1.8 3.3e-27 95.0 1.3 1.7 1 0 0 1 1 1 1 CASC3/Barentsz eIF4AIII binding Asp PF00026.18 EXF78154.1 - 3.9e-68 230.0 2.3 4.6e-68 229.7 1.6 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EXF78154.1 - 1e-08 35.3 0.0 6.7e-08 32.6 0.0 2.1 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EXF78154.1 - 6.8e-05 23.3 1.1 0.13 12.7 0.2 3.0 2 1 0 2 2 2 2 Aspartyl protease NKWYS PF10364.4 EXF78154.1 - 0.039 13.6 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein Aminotran_4 PF01063.14 EXF78155.1 - 1.1e-22 80.6 0.0 1.8e-22 79.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class IV TPR_11 PF13414.1 EXF78156.1 - 1e-55 185.2 17.0 6.4e-14 51.3 1.1 7.5 4 3 2 7 7 7 7 TPR repeat TPR_1 PF00515.23 EXF78156.1 - 4.4e-47 155.8 22.4 2.9e-06 26.6 0.0 11.4 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_2 PF07719.12 EXF78156.1 - 4.8e-44 144.7 16.8 9.5e-05 22.0 0.0 11.4 11 0 0 11 11 11 10 Tetratricopeptide repeat TPR_12 PF13424.1 EXF78156.1 - 3.3e-28 97.4 16.4 3.9e-07 29.8 0.0 7.5 2 2 6 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.1 EXF78156.1 - 2e-26 92.0 10.9 3e-05 24.5 0.1 6.8 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.1 EXF78156.1 - 2.6e-25 86.4 8.8 6.6e-05 22.7 0.0 9.4 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_8 PF13181.1 EXF78156.1 - 4.6e-20 69.8 13.7 0.0092 15.6 0.0 10.8 10 1 0 11 11 11 5 Tetratricopeptide repeat TPR_19 PF14559.1 EXF78156.1 - 3.4e-14 52.9 15.8 6.6e-06 26.3 0.4 6.4 5 2 1 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EXF78156.1 - 6.2e-14 51.2 19.4 0.034 14.7 0.4 9.7 4 3 6 11 11 10 3 Tetratricopeptide repeat TPR_7 PF13176.1 EXF78156.1 - 1e-12 46.8 17.6 0.024 14.4 0.1 9.4 8 2 2 10 10 10 3 Tetratricopeptide repeat TPR_9 PF13371.1 EXF78156.1 - 3.4e-12 46.0 5.6 7.5e-05 22.5 0.0 6.2 3 2 4 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EXF78156.1 - 1.9e-10 40.7 12.1 0.0044 17.1 0.1 5.6 2 1 3 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EXF78156.1 - 2e-07 31.0 14.3 4.7 7.8 0.4 8.7 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.1 EXF78156.1 - 2.1e-07 30.2 1.4 0.35 9.8 0.2 4.7 2 1 2 4 4 4 3 Tetratricopeptide repeat SHNi-TPR PF10516.4 EXF78156.1 - 2.8e-06 26.4 4.5 0.24 10.6 0.0 5.5 6 0 0 6 6 6 2 SHNi-TPR TPR_10 PF13374.1 EXF78156.1 - 0.0035 17.2 12.7 1.6 8.7 0.5 6.5 7 0 0 7 7 6 1 Tetratricopeptide repeat MAS20 PF02064.10 EXF78156.1 - 0.013 15.4 4.2 8.2 6.3 0.0 4.3 4 1 0 5 5 5 0 MAS20 protein import receptor TPR_4 PF07721.9 EXF78156.1 - 0.017 15.4 0.2 90 3.9 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.7 EXF78156.1 - 0.05 14.2 7.7 1.8 9.3 0.2 4.5 4 0 0 4 4 3 0 Sel1 repeat TPR_20 PF14561.1 EXF78156.1 - 0.53 10.4 0.1 0.53 10.4 0.0 4.8 6 1 1 7 7 4 0 Tetratricopeptide repeat NARP1 PF12569.3 EXF78156.1 - 2.3 6.8 24.4 0.4 9.3 1.4 4.8 2 1 1 4 4 4 0 NMDA receptor-regulated protein 1 TPR_3 PF07720.7 EXF78156.1 - 3.2 7.6 17.7 0.6 9.9 0.3 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF3597 PF12200.3 EXF78156.1 - 3.5 8.0 6.9 36 4.7 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) SNARE PF05739.14 EXF78157.1 - 8.8e-14 50.9 6.3 8.8e-14 50.9 4.4 2.0 2 0 0 2 2 1 1 SNARE domain Syntaxin PF00804.20 EXF78157.1 - 1.6e-10 41.0 1.9 1.6e-10 41.0 1.3 2.4 2 1 0 2 2 2 1 Syntaxin Use1 PF09753.4 EXF78157.1 - 0.0012 18.2 6.4 0.0017 17.8 4.4 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 FUSC PF04632.7 EXF78157.1 - 0.0036 15.8 9.9 0.0063 15.0 1.0 2.2 1 1 0 2 2 2 2 Fusaric acid resistance protein family ETRAMP PF09716.5 EXF78157.1 - 0.0091 15.9 0.6 0.022 14.6 0.0 1.9 2 0 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) Syntaxin_2 PF14523.1 EXF78157.1 - 0.0095 15.9 14.6 0.15 12.1 4.3 2.9 2 1 0 2 2 2 2 Syntaxin-like protein DUF2077 PF09850.4 EXF78157.1 - 0.039 13.3 2.1 0.063 12.6 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) DUF3094 PF11293.3 EXF78157.1 - 0.088 12.2 0.1 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3094) PBP1_TM PF14812.1 EXF78157.1 - 0.36 11.1 2.6 0.38 11.0 0.1 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3708 PF12501.3 EXF78157.1 - 0.42 10.4 7.4 0.44 10.3 0.5 2.4 2 1 0 2 2 2 0 Phosphate ATP-binding cassette transporter Allexi_40kDa PF05549.6 EXF78157.1 - 0.74 9.0 8.7 0.97 8.6 1.0 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein Fib_alpha PF08702.5 EXF78157.1 - 1.7 8.8 12.3 1.1 9.4 1.9 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Mnd1 PF03962.10 EXF78157.1 - 3.9 7.0 18.1 2.5 7.7 3.3 2.7 1 1 1 2 2 2 0 Mnd1 family Peptidase_C6 PF00851.13 EXF78157.1 - 4 5.9 8.5 0.47 9.0 0.7 2.0 1 1 1 2 2 2 0 Helper component proteinase Baculo_PEP_C PF04513.7 EXF78157.1 - 4.6 7.0 13.0 6.1 6.6 2.6 3.0 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tweety PF04906.8 EXF78157.1 - 5.8 5.2 8.5 0.81 8.0 1.8 2.2 1 1 1 2 2 2 0 Tweety Spc42p PF11544.3 EXF78157.1 - 7.6 6.5 9.5 0.17 11.8 1.2 2.3 4 0 0 4 4 1 0 Spindle pole body component Spc42p Bac_export_3 PF01313.14 EXF78157.1 - 9.8 5.9 7.2 1.7 8.3 1.3 2.1 2 0 0 2 2 2 0 Bacterial export proteins, family 3 Brix PF04427.13 EXF78158.1 - 0.00027 20.6 0.1 0.13 11.9 0.0 2.2 1 1 1 2 2 2 2 Brix domain CTNNBL PF08216.6 EXF78158.1 - 0.0051 16.3 0.0 0.0078 15.7 0.0 1.3 1 0 0 1 1 1 1 Catenin-beta-like, Arm-motif containing nuclear UPF1_Zn_bind PF09416.5 EXF78159.1 - 1.2e-71 239.2 1.9 1.2e-71 239.2 1.3 2.2 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.1 EXF78159.1 - 2.6e-60 203.2 0.0 5.2e-60 202.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EXF78159.1 - 1e-55 188.8 1.4 1.7e-55 188.1 1.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EXF78159.1 - 4.7e-14 51.8 0.5 1.1e-13 50.7 0.1 1.8 2 0 0 2 2 1 1 Part of AAA domain AAA_30 PF13604.1 EXF78159.1 - 4e-12 46.1 0.3 1.5e-10 40.9 0.2 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EXF78159.1 - 2.3e-06 27.5 0.0 4.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.9 EXF78159.1 - 0.0001 22.0 0.0 0.00025 20.7 0.0 1.7 1 0 0 1 1 1 1 Helicase Viral_helicase1 PF01443.13 EXF78159.1 - 0.00013 21.6 0.1 0.41 10.1 0.0 2.9 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.4 EXF78159.1 - 0.00064 18.7 0.7 0.0041 16.1 0.0 2.3 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.9 EXF78159.1 - 0.00085 18.3 0.0 0.26 10.1 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase UvrD-helicase PF00580.16 EXF78159.1 - 0.0014 17.9 0.0 0.028 13.7 0.0 2.2 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DEAD PF00270.24 EXF78159.1 - 0.0026 17.2 0.1 0.0056 16.2 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_16 PF13191.1 EXF78159.1 - 0.011 15.7 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain SRP54 PF00448.17 EXF78159.1 - 0.016 14.6 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain KaiC PF06745.8 EXF78159.1 - 0.033 13.3 0.0 0.066 12.3 0.0 1.4 1 0 0 1 1 1 0 KaiC UvrD_C_2 PF13538.1 EXF78159.1 - 0.11 12.6 0.0 0.35 11.0 0.0 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain SNF2_N PF00176.18 EXF78159.1 - 0.12 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_22 PF13401.1 EXF78159.1 - 0.15 12.2 0.0 0.42 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EXF78159.1 - 0.16 11.2 0.0 0.38 9.9 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Glyco_hydro_47 PF01532.15 EXF78160.1 - 2.3e-165 550.6 0.0 2.7e-165 550.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 RasGAP PF00616.14 EXF78161.1 - 4.4e-43 147.2 0.0 8.6e-43 146.3 0.0 1.5 1 1 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase Pro_isomerase PF00160.16 EXF78162.1 - 1e-45 155.7 0.1 1.5e-45 155.1 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EXF78162.1 - 4e-08 32.7 10.1 0.00013 21.5 1.4 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EXF78162.1 - 9.2e-06 25.2 8.4 0.00012 21.7 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EXF78162.1 - 0.00035 20.0 5.4 0.00042 19.8 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EXF78162.1 - 0.018 14.9 1.7 0.086 12.7 0.5 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.1 EXF78162.1 - 0.02 14.7 0.1 0.092 12.6 0.1 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.1 EXF78162.1 - 0.074 12.8 0.1 0.31 10.9 0.0 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.1 EXF78162.1 - 0.089 13.4 0.2 0.76 10.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EXF78162.1 - 1.5 9.5 9.0 0.16 12.7 0.8 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Tyr_Deacylase PF02580.11 EXF78163.1 - 1e-40 139.0 0.0 1.1e-40 138.9 0.0 1.0 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase Telomere_reg-2 PF10193.4 EXF78163.1 - 0.038 14.2 0.1 0.066 13.4 0.0 1.4 2 0 0 2 2 2 0 Telomere length regulation protein Not3 PF04065.10 EXF78164.1 - 1.4e-99 332.1 25.7 2.6e-99 331.2 17.8 1.4 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EXF78164.1 - 2.6e-42 143.8 6.0 2.6e-42 143.8 4.2 2.2 3 0 0 3 3 3 1 NOT2 / NOT3 / NOT5 family DUF2373 PF10180.4 EXF78164.1 - 0.006 16.1 3.6 0.013 15.0 2.5 1.5 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) DUF1192 PF06698.6 EXF78164.1 - 0.0082 15.9 2.0 0.0082 15.9 1.4 3.1 3 0 0 3 3 2 1 Protein of unknown function (DUF1192) SNARE PF05739.14 EXF78164.1 - 0.022 14.4 1.3 0.022 14.4 0.9 2.2 2 0 0 2 2 2 0 SNARE domain Cep57_MT_bd PF06657.8 EXF78164.1 - 0.064 13.2 10.5 0.15 12.0 0.7 2.9 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Snapin_Pallidin PF14712.1 EXF78164.1 - 0.11 12.8 10.1 0.15 12.4 0.4 2.6 2 0 0 2 2 2 0 Snapin/Pallidin Sec5 PF15469.1 EXF78164.1 - 0.62 9.7 12.5 0.52 10.0 1.7 2.5 2 0 0 2 2 2 0 Exocyst complex component Sec5 DivIC PF04977.10 EXF78164.1 - 2.3 7.7 10.2 4.7 6.7 1.0 3.1 2 0 0 2 2 2 0 Septum formation initiator TFIIA PF03153.8 EXF78164.1 - 6.2 6.6 34.2 3.6 7.3 10.4 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit V_ATPase_I PF01496.14 EXF78164.1 - 6.8 4.4 11.5 13 3.5 7.9 1.4 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C2H2_4 PF13894.1 EXF78165.1 - 0.087 13.2 0.2 0.087 13.2 0.1 4.1 4 0 0 4 4 4 0 C2H2-type zinc finger Sina PF03145.11 EXF78165.1 - 0.15 11.6 2.2 0.22 11.1 1.5 1.2 1 0 0 1 1 1 0 Seven in absentia protein family zf-C2H2 PF00096.21 EXF78165.1 - 0.18 12.2 0.1 0.18 12.2 0.1 4.1 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EXF78165.1 - 2.2 8.7 14.1 1.2 9.6 1.4 3.6 3 1 0 3 3 3 0 Zinc-finger double domain EMP70 PF02990.11 EXF78166.1 - 6.9e-163 542.8 3.4 7.6e-162 539.4 2.3 2.3 1 1 0 1 1 1 1 Endomembrane protein 70 Peptidase_M50 PF02163.17 EXF78166.1 - 0.74 8.7 3.6 3.6 6.4 2.5 2.2 1 1 0 1 1 1 0 Peptidase family M50 DUF3267 PF11667.3 EXF78166.1 - 1.8 8.7 16.2 0.09 12.9 1.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3267) ABC_tran PF00005.22 EXF78167.1 - 1.5e-50 171.0 0.0 3.8e-29 101.7 0.0 2.8 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EXF78167.1 - 6.6e-30 104.4 17.2 6.3e-16 58.6 0.4 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region SMC_N PF02463.14 EXF78167.1 - 3.6e-09 36.1 1.9 0.0091 15.2 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EXF78167.1 - 5e-09 36.5 0.0 0.27 11.1 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA_23 PF13476.1 EXF78167.1 - 1.8e-08 34.9 0.7 5e-05 23.7 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EXF78167.1 - 2.3e-07 30.3 0.0 0.015 14.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EXF78167.1 - 3.2e-07 29.7 1.5 0.0093 15.4 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain T2SE PF00437.15 EXF78167.1 - 3.3e-05 22.9 0.4 0.049 12.5 0.1 2.7 2 0 0 2 2 2 2 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EXF78167.1 - 5.7e-05 22.6 0.0 0.022 14.2 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 EXF78167.1 - 5.8e-05 23.2 2.9 0.78 9.8 0.1 3.9 2 2 0 2 2 2 2 AAA domain Miro PF08477.8 EXF78167.1 - 6.7e-05 23.3 0.1 0.51 10.8 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 EXF78167.1 - 0.0001 21.5 0.7 0.35 10.0 0.0 2.7 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EXF78167.1 - 0.00012 22.1 1.6 0.53 10.2 0.1 2.9 2 0 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.1 EXF78167.1 - 0.00015 21.5 0.0 0.46 10.4 0.0 3.1 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit Viral_helicase1 PF01443.13 EXF78167.1 - 0.00017 21.2 0.1 0.068 12.6 0.0 2.6 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EXF78167.1 - 0.00018 21.1 2.4 0.031 14.0 0.1 3.9 3 0 0 3 3 3 1 Part of AAA domain AAA_17 PF13207.1 EXF78167.1 - 0.00019 22.2 0.9 0.21 12.4 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EXF78167.1 - 0.00024 20.6 0.6 0.47 9.8 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain MobB PF03205.9 EXF78167.1 - 0.0003 20.4 1.0 0.1 12.3 0.1 2.9 3 0 0 3 3 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EXF78167.1 - 0.0015 18.2 0.3 2 8.0 0.0 2.6 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 EXF78167.1 - 0.0015 18.8 0.3 3.3 8.0 0.0 3.0 3 0 0 3 3 2 1 AAA domain DUF87 PF01935.12 EXF78167.1 - 0.0017 18.2 5.1 0.0037 17.1 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF87 cobW PF02492.14 EXF78167.1 - 0.0021 17.5 2.2 0.64 9.4 0.7 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain Pox_A32 PF04665.7 EXF78167.1 - 0.0021 17.3 1.1 0.51 9.5 0.0 2.3 2 0 0 2 2 2 1 Poxvirus A32 protein AAA_33 PF13671.1 EXF78167.1 - 0.0028 17.5 0.0 4.4 7.1 0.0 3.0 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EXF78167.1 - 0.003 17.4 3.2 0.12 12.3 0.0 3.0 3 0 0 3 3 2 1 50S ribosome-binding GTPase NB-ARC PF00931.17 EXF78167.1 - 0.0041 16.0 0.4 3.1 6.5 0.0 2.9 2 1 0 2 2 2 1 NB-ARC domain Dynamin_N PF00350.18 EXF78167.1 - 0.013 15.3 2.1 2.7 7.7 0.2 2.6 2 0 0 2 2 2 0 Dynamin family AAA_14 PF13173.1 EXF78167.1 - 0.042 13.7 0.1 5.6 6.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EXF78167.1 - 0.068 12.1 0.1 0.6 9.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 EXF78167.1 - 0.093 12.4 2.2 6.4 6.4 0.0 2.5 2 0 0 2 2 2 0 NTPase Arch_ATPase PF01637.13 EXF78167.1 - 0.14 11.8 0.0 2.6 7.6 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase Septin PF00735.13 EXF78167.1 - 0.18 10.7 0.2 14 4.5 0.0 2.3 2 0 0 2 2 2 0 Septin KaiC PF06745.8 EXF78167.1 - 0.21 10.6 3.4 31 3.5 0.0 3.2 2 1 1 3 3 3 0 KaiC AAA_15 PF13175.1 EXF78167.1 - 0.49 9.3 0.1 1.8 7.5 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain ATP_bind_1 PF03029.12 EXF78167.1 - 0.61 9.5 2.3 6.9 6.1 0.0 2.5 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Aldolase_II PF00596.16 EXF78168.1 - 5.5e-43 146.7 0.0 8.5e-43 146.0 0.0 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF3148 PF11347.3 EXF78168.1 - 0.013 15.1 0.0 0.04 13.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3148) Nol1_Nop2_Fmu PF01189.12 EXF78169.1 - 3.4e-34 118.5 0.0 2e-22 79.9 0.0 4.5 3 2 1 4 4 4 4 NOL1/NOP2/sun family Methyltransf_26 PF13659.1 EXF78169.1 - 0.074 13.0 0.0 0.074 13.0 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain DHQ_synthase PF01761.15 EXF78170.1 - 4.7e-54 183.0 0.0 7.2e-54 182.4 0.0 1.2 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.1 EXF78170.1 - 6.5e-14 51.8 0.0 1e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.14 EXF78170.1 - 0.00072 18.2 0.0 0.0011 17.7 0.0 1.3 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Methyltransf_3 PF01596.12 EXF78171.1 - 7e-13 48.0 0.0 1e-12 47.5 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EXF78171.1 - 1.5e-08 35.4 0.0 2.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CmcI PF04989.7 EXF78171.1 - 0.12 11.6 0.0 0.28 10.4 0.0 1.5 2 0 0 2 2 2 0 Cephalosporin hydroxylase Mito_carr PF00153.22 EXF78172.1 - 5e-60 199.2 4.2 1.4e-21 75.9 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein MT-A70 PF05063.9 EXF78173.1 - 3.5e-31 108.0 0.0 5.1e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 MT-A70 Methyltransf_26 PF13659.1 EXF78173.1 - 2.1e-06 27.7 0.1 3.5e-06 27.0 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ribosomal_L23 PF00276.15 EXF78174.1 - 8.9e-16 57.6 0.0 1.5e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L23 XdhC_CoxI PF02625.11 EXF78174.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.4 1 0 0 1 1 1 0 XdhC and CoxI family DUF4066 PF13278.1 EXF78175.1 - 5.2e-24 84.3 0.1 5.3e-20 71.3 0.0 2.0 2 0 0 2 2 2 2 Putative amidotransferase DJ-1_PfpI PF01965.19 EXF78175.1 - 6.6e-06 25.6 0.0 1.7e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family Hamartin PF04388.7 EXF78176.1 - 1.9e-43 149.1 17.6 3e-43 148.4 12.2 1.2 1 0 0 1 1 1 1 Hamartin protein ABC_membrane PF00664.18 EXF78177.1 - 7.2e-75 251.9 33.2 2.4e-44 151.8 5.5 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EXF78177.1 - 1.5e-60 203.4 0.0 5.7e-29 101.1 0.0 3.2 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EXF78177.1 - 2.1e-14 53.3 0.0 5.1e-07 29.1 0.0 3.8 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EXF78177.1 - 1.3e-11 45.0 0.3 0.014 15.3 0.1 4.0 2 2 1 3 3 3 3 AAA domain AAA_16 PF13191.1 EXF78177.1 - 5.2e-11 42.8 0.0 0.0049 16.8 0.0 3.8 3 1 0 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EXF78177.1 - 1e-08 36.0 0.0 0.0051 17.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EXF78177.1 - 1.1e-08 35.2 0.1 0.0086 16.2 0.0 4.0 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EXF78177.1 - 2.2e-08 33.5 0.4 0.00034 20.0 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EXF78177.1 - 1.7e-07 30.2 0.2 0.0029 16.2 0.0 2.6 2 0 0 2 2 2 2 Predicted ATPase of the ABC class DUF258 PF03193.11 EXF78177.1 - 1.9e-07 30.4 0.0 0.023 13.8 0.0 2.6 2 1 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EXF78177.1 - 8.7e-06 25.5 2.9 0.11 12.4 0.1 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EXF78177.1 - 1.2e-05 25.6 0.0 0.16 12.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EXF78177.1 - 1.9e-05 24.2 0.2 0.078 12.4 0.0 3.8 4 0 0 4 4 4 1 AAA-like domain AAA_19 PF13245.1 EXF78177.1 - 1.9e-05 24.2 0.2 1.2 8.9 0.0 3.9 3 0 0 3 3 3 1 Part of AAA domain AAA_25 PF13481.1 EXF78177.1 - 2.8e-05 23.6 0.3 1.1 8.5 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA_5 PF07728.9 EXF78177.1 - 3.6e-05 23.5 0.0 0.55 9.9 0.0 3.6 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_30 PF13604.1 EXF78177.1 - 5.8e-05 22.7 0.0 3 7.3 0.0 4.2 4 0 0 4 4 4 1 AAA domain ATP-synt_ab PF00006.20 EXF78177.1 - 7.9e-05 22.2 0.1 0.51 9.8 0.0 3.4 3 0 0 3 3 3 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.24 EXF78177.1 - 9e-05 22.6 2.9 0.73 10.0 0.4 4.2 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EXF78177.1 - 0.00018 21.4 0.0 0.39 10.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EXF78177.1 - 0.00025 20.4 0.6 0.099 12.0 0.0 3.3 4 0 0 4 4 3 1 IstB-like ATP binding protein AAA_28 PF13521.1 EXF78177.1 - 0.00044 20.2 0.0 1.2 9.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EXF78177.1 - 0.00064 20.0 0.3 0.93 9.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EXF78177.1 - 0.00083 19.0 0.0 2.1 8.0 0.0 2.9 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 EXF78177.1 - 0.0027 17.1 0.0 2.7 7.3 0.0 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_14 PF13173.1 EXF78177.1 - 0.003 17.4 0.0 8.4 6.3 0.0 3.8 4 0 0 4 4 4 0 AAA domain ATP_bind_1 PF03029.12 EXF78177.1 - 0.0051 16.3 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein Rad17 PF03215.10 EXF78177.1 - 0.01 14.5 0.0 1 7.9 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein RNA_helicase PF00910.17 EXF78177.1 - 0.021 15.0 0.0 5.6 7.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.10 EXF78177.1 - 0.072 12.8 0.1 51 3.5 0.0 3.7 4 0 0 4 4 4 0 NTPase APS_kinase PF01583.15 EXF78177.1 - 0.072 12.7 0.0 11 5.6 0.0 3.5 4 0 0 4 4 3 0 Adenylylsulphate kinase NB-ARC PF00931.17 EXF78177.1 - 0.074 11.8 0.1 12 4.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain MMR_HSR1 PF01926.18 EXF78177.1 - 0.095 12.6 0.0 9.9 6.1 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_24 PF13479.1 EXF78177.1 - 0.17 11.4 0.0 19 4.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain Glyco_hydro_17 PF00332.13 EXF78179.1 - 0.0004 19.5 0.7 0.00087 18.4 0.5 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 GTP1_OBG PF01018.17 EXF78180.1 - 3.1e-36 124.3 0.2 1.2e-27 96.4 0.6 2.5 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EXF78180.1 - 6e-22 77.7 0.0 1.2e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EXF78180.1 - 7.2e-08 31.8 0.1 2.2e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EXF78180.1 - 0.022 14.2 0.0 2.4 7.5 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EXF78180.1 - 0.024 14.9 0.5 0.06 13.6 0.0 1.9 2 0 0 2 2 2 0 ABC transporter ArgK PF03308.11 EXF78180.1 - 0.047 12.4 5.5 0.39 9.4 0.0 2.8 3 0 0 3 3 3 0 ArgK protein Arf PF00025.16 EXF78180.1 - 0.24 10.6 0.0 1.1 8.5 0.0 1.9 2 0 0 2 2 2 0 ADP-ribosylation factor family Dynamin_N PF00350.18 EXF78180.1 - 0.33 10.7 0.8 5.7 6.7 0.0 3.1 4 0 0 4 4 4 0 Dynamin family GCV_T PF01571.16 EXF78182.1 - 2.9e-56 190.1 0.0 4.2e-56 189.6 0.0 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EXF78182.1 - 8.7e-23 80.1 0.8 1.6e-22 79.2 0.5 1.5 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Phage-tail_3 PF13550.1 EXF78182.1 - 0.0071 16.1 0.0 0.018 14.8 0.0 1.6 2 0 0 2 2 2 1 Putative phage tail protein Rhomboid PF01694.17 EXF78183.1 - 2.1e-14 53.7 9.8 2.1e-14 53.7 6.8 1.9 2 0 0 2 2 2 1 Rhomboid family C_GCAxxG_C_C PF09719.5 EXF78183.1 - 0.11 12.2 0.0 0.3 10.8 0.0 1.6 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) 5TM-5TMR_LYT PF07694.7 EXF78183.1 - 0.69 9.2 9.6 0.14 11.4 2.9 2.3 2 1 1 3 3 3 0 5TMR of 5TMR-LYT Aconitase PF00330.15 EXF78184.1 - 6.5e-175 582.0 0.0 1.1e-174 581.2 0.0 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EXF78184.1 - 1.9e-44 150.9 0.0 3.4e-44 150.1 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain LCE PF14672.1 EXF78185.1 - 5.7 7.4 7.2 4.9 7.7 2.4 2.3 1 1 1 2 2 2 0 Late cornified envelope Metallophos PF00149.23 EXF78186.1 - 5.8e-08 32.3 1.3 2e-07 30.6 0.9 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Daxx PF03344.10 EXF78186.1 - 0.56 8.6 19.8 1.1 7.6 13.7 1.4 1 0 0 1 1 1 0 Daxx Family Hid1 PF12722.2 EXF78186.1 - 4.8 4.7 5.6 6.1 4.3 3.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.9 EXF78186.1 - 8.7 4.2 28.8 0.18 9.7 14.2 2.1 3 0 0 3 3 3 0 CDC45-like protein Ofd1_CTDD PF10637.4 EXF78187.1 - 9.6e-100 333.1 0.0 1.4e-91 306.3 0.0 2.1 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_3 PF13640.1 EXF78187.1 - 1.3e-14 54.4 0.0 3.4e-14 53.1 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EXF78187.1 - 0.014 15.0 0.0 0.048 13.3 0.0 1.9 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Paf1 PF03985.8 EXF78187.1 - 2.6 6.7 10.2 4.7 5.8 0.0 2.3 2 0 0 2 2 2 0 Paf1 Aminotran_5 PF00266.14 EXF78188.1 - 1.3e-56 191.9 0.0 1.7e-56 191.5 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EXF78188.1 - 0.00019 19.8 0.0 0.00029 19.2 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EXF78188.1 - 0.016 14.1 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Ribul_P_3_epim PF00834.14 EXF78189.1 - 8e-59 198.1 0.0 2.8e-57 193.0 0.0 2.7 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family ThiG PF05690.9 EXF78189.1 - 0.015 14.4 0.1 0.021 13.8 0.1 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG OMPdecase PF00215.19 EXF78189.1 - 0.015 14.6 0.1 0.028 13.8 0.0 1.5 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family QRPTase_C PF01729.14 EXF78189.1 - 0.063 12.8 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Glyco_hydro_31 PF01055.21 EXF78189.1 - 0.071 11.9 0.0 0.1 11.4 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 V-ATPase_H_N PF03224.9 EXF78190.1 - 6.1e-74 248.9 0.0 8.3e-74 248.5 0.0 1.2 1 0 0 1 1 1 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EXF78190.1 - 1.5e-38 131.3 0.1 5.4e-38 129.5 0.0 2.0 2 0 0 2 2 2 1 V-ATPase subunit H DUF4131 PF13567.1 EXF78191.1 - 0.011 15.1 0.0 0.047 13.1 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1517 PF07466.6 EXF78191.1 - 0.012 14.6 1.1 0.012 14.6 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) TILa PF12714.2 EXF78191.1 - 6.2 6.6 19.7 0.52 10.0 3.2 3.2 2 1 0 2 2 2 0 TILa domain Ribosomal_L6 PF00347.18 EXF78192.1 - 1.8e-26 92.4 7.4 1.3e-13 51.2 2.4 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Vps26 PF03643.10 EXF78193.1 - 6.4e-126 418.7 1.6 3.7e-125 416.2 1.1 1.8 1 1 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EXF78193.1 - 1e-05 25.3 0.0 0.0011 18.8 0.0 2.6 1 1 1 2 2 2 1 Arrestin (or S-antigen), N-terminal domain DUF432 PF04254.8 EXF78193.1 - 0.078 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF432) Tim54 PF11711.3 EXF78194.1 - 2.5e-119 398.2 0.8 3.5e-119 397.8 0.6 1.2 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Nefa_Nip30_N PF10187.4 EXF78195.1 - 4.3e-23 81.4 12.6 4.3e-23 81.4 8.7 2.5 2 0 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 DUF3451 PF11933.3 EXF78195.1 - 4.3 7.0 11.6 0.36 10.5 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3451) Cyclin PF08613.6 EXF78196.1 - 5e-14 52.9 0.0 7.9e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EXF78196.1 - 0.079 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain Methyltransf_2 PF00891.13 EXF78198.1 - 1.5e-29 102.8 0.0 2.4e-29 102.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase MarR_2 PF12802.2 EXF78198.1 - 4.5e-05 23.0 0.0 9.9e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 MarR family HTH_27 PF13463.1 EXF78198.1 - 0.081 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Winged helix DNA-binding domain CRC_subunit PF08624.5 EXF78200.1 - 1.4e-57 193.5 0.0 2.1e-57 192.9 0.0 1.3 1 0 0 1 1 1 1 Chromatin remodelling complex Rsc7/Swp82 subunit Daxx PF03344.10 EXF78200.1 - 0.0073 14.8 20.2 0.011 14.2 14.0 1.2 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 EXF78200.1 - 0.018 13.0 16.4 0.023 12.6 11.4 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EXF78200.1 - 0.061 11.3 9.1 0.085 10.8 6.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2890 PF11081.3 EXF78200.1 - 0.11 12.4 13.9 0.23 11.5 9.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) CT47 PF15623.1 EXF78200.1 - 1.4 8.5 26.2 2.5 7.7 18.2 1.3 1 0 0 1 1 1 0 Cancer/testis gene family 47 DUF1510 PF07423.6 EXF78200.1 - 5.5 6.2 17.3 10 5.4 12.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SDA1 PF05285.7 EXF78200.1 - 7.8 5.6 20.2 17 4.5 14.0 1.4 1 0 0 1 1 1 0 SDA1 TFIIB PF00382.14 EXF78201.1 - 7.6e-42 140.9 1.2 9.1e-23 79.8 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EXF78201.1 - 5.7e-14 51.1 1.8 1e-13 50.3 1.3 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_Tnp_ISL3 PF13542.1 EXF78201.1 - 0.0097 15.0 0.1 0.064 12.4 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of transposase family ISL3 DUF3287 PF11690.3 EXF78201.1 - 0.091 12.8 0.4 0.52 10.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) zf-LITAF-like PF10601.4 EXF78201.1 - 0.17 11.8 3.7 0.25 11.2 0.0 2.5 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Trp_repressor PF01371.14 EXF78201.1 - 0.3 11.0 2.6 20 5.1 0.0 2.9 3 0 0 3 3 3 0 Trp repressor protein ArsB PF02040.10 EXF78202.1 - 2.6e-16 59.6 17.1 1.2e-11 44.2 4.7 2.4 2 0 0 2 2 2 2 Arsenical pump membrane protein CoA_transf_3 PF02515.12 EXF78203.1 - 2.6e-59 199.6 0.0 5.9e-59 198.5 0.0 1.6 2 0 0 2 2 2 1 CoA-transferase family III NfeD PF01957.13 EXF78203.1 - 0.35 11.0 1.7 0.37 10.9 0.2 1.7 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding PHD PF00628.24 EXF78204.1 - 0.0023 17.6 5.3 0.0023 17.6 3.7 1.7 2 0 0 2 2 2 1 PHD-finger DUF2397 PF09660.5 EXF78205.1 - 0.18 10.3 0.6 0.25 9.8 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2397) MFS_1 PF07690.11 EXF78208.1 - 3.9e-26 91.6 31.1 1.2e-17 63.7 12.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF78208.1 - 0.0022 16.6 21.5 0.0033 16.0 9.0 2.2 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 EXF78208.1 - 0.0031 17.2 1.8 0.027 14.2 0.2 2.8 3 0 0 3 3 3 1 MFS_1 like family DUF3176 PF11374.3 EXF78209.1 - 8.3e-33 112.5 0.7 8.3e-33 112.5 0.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Asn_synthase PF00733.16 EXF78210.1 - 1.3e-56 191.9 0.0 2e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EXF78210.1 - 2.6e-08 33.6 0.0 1.5e-07 31.2 0.0 2.2 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EXF78210.1 - 1.3e-05 25.2 0.0 3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EXF78210.1 - 0.012 14.7 0.0 0.02 14.1 0.0 1.2 1 0 0 1 1 1 0 Aluminium induced protein 3HCDH_N PF02737.13 EXF78211.1 - 1.9e-21 76.5 0.0 2.6e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EXF78211.1 - 3.2e-14 53.0 0.0 4.9e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ACDC PF14733.1 EXF78213.1 - 0.16 12.1 0.0 0.5 10.5 0.0 1.9 2 0 0 2 2 2 0 AP2-coincident C-terminal TAFH PF07531.9 EXF78214.1 - 0.098 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 NHR1 homology to TAF DUF2430 PF10353.4 EXF78214.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2430) Peptidase_M28 PF04389.12 EXF78215.1 - 4.5e-39 134.0 0.0 5.9e-39 133.6 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 MFS_1 PF07690.11 EXF78216.1 - 2.4e-31 108.7 48.5 3.7e-30 104.8 33.6 2.3 1 1 0 1 1 1 1 Major Facilitator Superfamily HSP70 PF00012.15 EXF78216.1 - 8.5e-15 53.6 0.0 1.8e-13 49.2 0.0 2.0 2 0 0 2 2 2 2 Hsp70 protein Sugar_tr PF00083.19 EXF78216.1 - 0.00066 18.3 11.6 0.00066 18.3 8.1 3.2 2 1 1 3 3 3 1 Sugar (and other) transporter PilM_2 PF11104.3 EXF78216.1 - 0.12 11.1 0.0 0.26 10.1 0.0 1.4 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; APG6 PF04111.7 EXF78217.1 - 0.017 14.2 12.8 0.026 13.5 8.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 AAA_27 PF13514.1 EXF78217.1 - 0.02 12.5 12.2 0.028 12.1 8.4 1.0 1 0 0 1 1 1 0 AAA domain DUF2408 PF10303.4 EXF78217.1 - 0.023 14.7 2.9 0.047 13.7 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) Sigma70_ner PF04546.8 EXF78217.1 - 0.067 12.7 11.8 0.11 12.1 8.2 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region AATF-Che1 PF13339.1 EXF78217.1 - 0.094 12.8 8.5 13 5.9 6.5 2.9 2 1 0 2 2 2 0 Apoptosis antagonizing transcription factor IncA PF04156.9 EXF78217.1 - 0.14 11.7 14.6 0.24 10.9 10.1 1.3 1 0 0 1 1 1 0 IncA protein DUF342 PF03961.8 EXF78217.1 - 0.21 9.9 3.7 0.35 9.2 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF342) AAA_23 PF13476.1 EXF78217.1 - 0.54 10.5 4.3 1.1 9.5 3.0 1.5 1 0 0 1 1 1 0 AAA domain MIF4G_like_2 PF09090.6 EXF78217.1 - 0.71 9.0 4.9 1.2 8.3 3.4 1.3 1 0 0 1 1 1 0 MIF4G like CDC37_N PF03234.9 EXF78217.1 - 0.92 9.8 9.1 0.6 10.4 4.6 1.9 2 0 0 2 2 2 0 Cdc37 N terminal kinase binding Prefoldin_2 PF01920.15 EXF78217.1 - 1.1 9.0 14.0 1.6 8.5 0.5 2.9 4 0 0 4 4 2 0 Prefoldin subunit DUF2937 PF11157.3 EXF78217.1 - 1.2 8.4 6.0 1.3 8.3 1.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2937) Fib_alpha PF08702.5 EXF78217.1 - 1.5 8.9 5.5 6.7 6.8 3.8 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Fmp27_WPPW PF10359.4 EXF78217.1 - 1.8 6.9 10.3 4.7 5.4 7.2 1.5 1 1 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain FUSC PF04632.7 EXF78217.1 - 1.9 6.8 3.1 2.5 6.4 2.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Takusan PF04822.8 EXF78217.1 - 2.3 8.0 7.4 0.64 9.8 2.7 1.9 2 0 0 2 2 1 0 Takusan TMF_DNA_bd PF12329.3 EXF78217.1 - 2.3 8.0 15.3 1.4 8.8 1.8 2.5 1 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Pox_A_type_inc PF04508.7 EXF78217.1 - 3.7 7.5 7.1 32 4.6 1.6 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF4200 PF13863.1 EXF78217.1 - 4.6 7.2 22.6 1.3 8.9 2.1 2.5 2 1 1 3 3 2 0 Domain of unknown function (DUF4200) FliD_N PF02465.13 EXF78217.1 - 5.3 7.4 5.8 1.5 9.2 0.7 2.1 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus DUF1664 PF07889.7 EXF78217.1 - 5.4 6.8 5.5 28 4.4 3.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF2205 PF10224.4 EXF78217.1 - 7.7 6.1 8.6 13 5.4 0.2 2.8 3 0 0 3 3 2 0 Predicted coiled-coil protein (DUF2205) MFS_1 PF07690.11 EXF78218.1 - 5.3e-35 120.7 45.5 1.2e-30 106.3 28.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EXF78218.1 - 0.00024 21.0 0.8 0.00024 21.0 0.5 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1228) Tom5 PF10642.4 EXF78218.1 - 0.043 13.4 0.0 0.16 11.6 0.0 1.9 1 0 0 1 1 1 0 Mitochondrial import receptor subunit or translocase CorA PF01544.13 EXF78219.1 - 0.0029 16.7 1.6 0.0029 16.7 1.1 1.9 2 1 0 2 2 2 1 CorA-like Mg2+ transporter protein CAP PF00188.21 EXF78220.1 - 4.6e-11 43.2 0.0 7e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DPBB_1 PF03330.13 EXF78220.1 - 1.7e-05 24.6 0.0 3.2e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EXF78220.1 - 0.024 14.3 0.3 0.044 13.4 0.2 1.4 1 0 0 1 1 1 0 Barwin family Amidoligase_2 PF12224.3 EXF78221.1 - 2.1e-25 89.8 0.0 2.6e-13 50.2 0.0 5.0 5 1 0 5 5 5 3 Putative amidoligase enzyme IRF-2BP1_2 PF11261.3 EXF78221.1 - 0.19 11.2 0.2 0.66 9.4 0.0 2.0 2 0 0 2 2 2 0 Interferon regulatory factor 2-binding protein zinc finger SNF5 PF04855.7 EXF78222.1 - 2e-83 279.6 0.0 2.7e-83 279.1 0.0 1.1 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 GATA PF00320.22 EXF78222.1 - 0.027 13.7 5.0 0.07 12.4 3.5 1.8 1 0 0 1 1 1 0 GATA zinc finger Glyco_hydro_7 PF00840.15 EXF78223.1 - 1e-189 630.4 19.4 1e-189 630.4 13.4 1.7 2 1 0 2 2 2 1 Glycosyl hydrolase family 7 CBM_1 PF00734.13 EXF78223.1 - 1.2e-12 47.2 13.7 1.2e-12 47.2 9.5 4.8 4 1 0 5 5 5 1 Fungal cellulose binding domain Fungal_trans PF04082.13 EXF78224.1 - 6.4e-13 48.1 0.0 1.1e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EXF78226.1 - 1.5e-22 79.7 0.4 3.3e-22 78.5 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF106 PF01956.11 EXF78226.1 - 0.07 12.6 0.4 0.22 11.0 0.3 1.8 1 0 0 1 1 1 0 Integral membrane protein DUF106 PAT1 PF09770.4 EXF78226.1 - 0.56 8.3 40.0 0.79 7.8 27.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Sugar_tr PF00083.19 EXF78227.1 - 5.5e-96 321.8 24.2 6.3e-96 321.6 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF78227.1 - 5.9e-32 110.7 26.5 8.4e-26 90.5 2.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EXF78227.1 - 3.5e-06 25.6 32.0 5.2e-05 21.8 4.0 3.2 2 2 0 3 3 3 2 MFS/sugar transport protein Cluap1 PF10234.4 EXF78228.1 - 2.9 7.0 5.5 0.3 10.2 0.7 1.6 2 0 0 2 2 2 0 Clusterin-associated protein-1 Glyco_hydro_2_C PF02836.12 EXF78230.1 - 0.0097 14.8 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Fungal_trans_2 PF11951.3 EXF78231.1 - 1.2e-05 24.1 0.0 2.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain RRXRR PF14239.1 EXF78231.1 - 0.081 12.3 0.8 0.13 11.6 0.5 1.3 1 0 0 1 1 1 0 RRXRR protein Alpha_L_fucos PF01120.12 EXF78234.1 - 2.2e-86 289.9 5.4 2.9e-86 289.5 3.7 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase GHL6 PF14871.1 EXF78234.1 - 0.047 13.7 0.4 0.13 12.2 0.0 1.9 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Lipase_3 PF01764.20 EXF78235.1 - 4.4e-07 29.6 0.0 1.2e-06 28.1 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EXF78235.1 - 0.08 12.7 0.0 0.22 11.2 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EXF78235.1 - 0.12 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Cutinase PF01083.17 EXF78236.1 - 2.2e-44 151.3 3.1 2.9e-44 150.9 2.1 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EXF78236.1 - 2.9e-06 26.8 0.1 5.4e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 EXF78236.1 - 0.11 12.3 0.0 0.17 11.6 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) SH3_2 PF07653.12 EXF78236.1 - 0.15 11.6 0.1 0.71 9.4 0.0 2.2 3 0 0 3 3 3 0 Variant SH3 domain Glyco_hydro_43 PF04616.9 EXF78237.1 - 1.3e-47 162.2 3.4 1.7e-47 161.8 2.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GST_N PF02798.15 EXF78238.1 - 5.3e-09 36.1 0.0 1.1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EXF78238.1 - 2.4e-08 34.0 0.0 4.2e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EXF78238.1 - 5.1e-07 29.5 0.0 8.1e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EXF78238.1 - 9.2e-07 28.6 0.0 3.1e-06 26.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EXF78238.1 - 6e-05 22.9 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EXF78238.1 - 0.00038 20.8 0.0 0.0006 20.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Fungal_trans PF04082.13 EXF78239.1 - 2.5e-08 33.1 0.2 6.2e-08 31.8 0.1 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain DIOX_N PF14226.1 EXF78240.1 - 9.7e-13 48.6 0.0 8e-12 45.7 0.0 2.1 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EXF78240.1 - 6.6e-10 39.1 0.0 1.2e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EXF78241.1 - 1.4e-32 112.7 17.5 1.4e-32 112.7 12.1 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Baculo_11_kDa PF06143.6 EXF78241.1 - 0.31 10.4 1.9 0.7 9.2 1.3 1.5 1 0 0 1 1 1 0 Baculovirus 11 kDa family Zn_clus PF00172.13 EXF78242.1 - 2.8e-09 36.7 8.1 5.7e-09 35.7 5.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF78242.1 - 5.3e-08 31.8 0.3 8.3e-08 31.2 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain 2OG-FeII_Oxy PF03171.15 EXF78242.1 - 0.00081 19.6 0.0 0.0037 17.5 0.0 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Fungal_trans PF04082.13 EXF78242.1 - 0.0032 16.3 0.1 0.01 14.7 0.0 1.8 1 1 1 2 2 2 1 Fungal specific transcription factor domain ADH_N PF08240.7 EXF78243.1 - 1.5e-22 79.3 2.4 4.6e-22 77.8 1.2 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF78243.1 - 1.3e-20 73.2 0.4 2.5e-20 72.3 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase TrkA_N PF02254.13 EXF78243.1 - 0.062 13.2 0.5 0.11 12.5 0.3 1.4 1 0 0 1 1 1 0 TrkA-N domain p450 PF00067.17 EXF78245.1 - 5.1e-51 173.6 0.1 6.6e-51 173.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 RTA1 PF04479.8 EXF78246.1 - 1.1e-55 188.5 2.1 1.1e-55 188.5 1.4 1.3 2 0 0 2 2 2 1 RTA1 like protein DUF4173 PF13777.1 EXF78246.1 - 0.093 12.0 4.3 3.8 6.7 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4173) Cation_ATPase_C PF00689.16 EXF78246.1 - 1.8 8.0 8.0 2.3 7.7 0.6 2.7 2 2 0 2 2 2 0 Cation transporting ATPase, C-terminus 7TMR-DISM_7TM PF07695.6 EXF78246.1 - 2 8.0 15.2 0.084 12.5 2.4 2.4 2 1 0 2 2 2 0 7TM diverse intracellular signalling Glyco_transf_28 PF03033.15 EXF78247.1 - 1.5e-25 89.5 0.0 1e-24 86.8 0.0 2.4 3 0 0 3 3 3 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EXF78247.1 - 0.00048 18.7 0.0 0.00082 18.0 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Cnd3 PF12719.2 EXF78248.1 - 0.35 9.8 9.2 47 2.8 2.0 4.7 1 1 2 3 3 3 0 Nuclear condensing complex subunits, C-term domain DUF4328 PF14219.1 EXF78248.1 - 1.5 8.0 18.9 24 4.1 0.1 7.7 4 4 3 7 7 7 0 Domain of unknown function (DUF4328) Lactamase_B PF00753.22 EXF78249.1 - 1.1e-20 74.1 0.0 2.5e-20 72.9 0.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EXF78249.1 - 1.1e-08 34.8 0.0 1.6e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EXF78249.1 - 0.019 14.6 0.3 0.063 12.9 0.2 1.9 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Tautomerase_3 PF14832.1 EXF78250.1 - 7.9e-43 145.7 0.0 9e-43 145.5 0.0 1.0 1 0 0 1 1 1 1 Putative oxalocrotonate tautomerase enzyme Tautomerase PF01361.16 EXF78250.1 - 0.03 13.9 0.0 0.07 12.7 0.0 1.6 1 1 0 1 1 1 0 Tautomerase enzyme MutS_III PF05192.13 EXF78251.1 - 0.055 13.2 0.1 0.23 11.2 0.1 2.0 1 1 0 1 1 1 0 MutS domain III WSC PF01822.14 EXF78252.1 - 6.8e-07 29.1 10.7 1.1e-06 28.4 7.4 1.3 1 0 0 1 1 1 1 WSC domain DUF2927 PF11150.3 EXF78252.1 - 0.11 12.1 1.1 0.16 11.5 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2927) VPS9 PF02204.13 EXF78253.1 - 3.7e-30 104.0 0.1 6.9e-30 103.1 0.1 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EXF78253.1 - 2.1e-10 39.8 0.6 9.4e-10 37.7 0.0 2.2 2 0 0 2 2 2 1 CUE domain Cutinase PF01083.17 EXF78254.1 - 8.7e-51 172.1 3.5 1e-50 171.9 2.5 1.1 1 0 0 1 1 1 1 Cutinase VirJ PF06057.6 EXF78254.1 - 4.5e-05 23.3 0.0 6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) PE-PPE PF08237.6 EXF78254.1 - 0.0046 16.4 0.1 0.0063 15.9 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_2 PF02230.11 EXF78254.1 - 0.0048 16.3 0.1 0.13 11.7 0.0 2.1 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EXF78254.1 - 0.046 13.4 0.1 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_3 PF01764.20 EXF78254.1 - 0.063 12.8 0.0 0.09 12.3 0.0 1.4 1 1 0 1 1 1 0 Lipase (class 3) Thioesterase PF00975.15 EXF78254.1 - 0.091 12.9 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain p450 PF00067.17 EXF78255.1 - 2.3e-25 89.0 0.0 1.7e-22 79.6 0.0 2.3 2 0 0 2 2 2 2 Cytochrome P450 E1-E2_ATPase PF00122.15 EXF78255.1 - 4.5e-17 61.8 0.0 1.9e-16 59.7 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EXF78255.1 - 3e-14 53.9 0.1 5.7e-11 43.2 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EXF78255.1 - 1.4e-12 48.1 0.2 5.1e-11 43.0 0.1 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EXF78255.1 - 1.9e-10 40.5 0.0 5.3e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit DUF4254 PF14063.1 EXF78255.1 - 0.015 14.9 0.2 0.032 13.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) Hydrolase_3 PF08282.7 EXF78255.1 - 0.019 14.5 0.0 0.09 12.3 0.0 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase HSBP1 PF06825.7 EXF78256.1 - 0.0036 16.8 0.5 0.85 9.2 0.0 3.3 4 0 0 4 4 4 1 Heat shock factor binding protein 1 Bacillus_HBL PF05791.6 EXF78256.1 - 0.0055 16.0 7.3 0.57 9.5 0.0 3.2 2 1 1 3 3 3 2 Bacillus haemolytic enterotoxin (HBL) DUF2095 PF09868.4 EXF78256.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) Mating_C PF12737.2 EXF78256.1 - 0.021 13.7 0.1 0.026 13.4 0.1 1.2 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 DUF3782 PF12644.2 EXF78256.1 - 0.12 12.1 0.6 1.1 9.0 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) HalX PF08663.5 EXF78256.1 - 0.17 11.9 4.7 0.75 9.8 0.0 3.3 2 1 0 2 2 2 0 HalX domain Filament PF00038.16 EXF78256.1 - 0.66 9.3 8.1 2 7.7 0.2 3.1 2 1 1 3 3 3 0 Intermediate filament protein MFS_1 PF07690.11 EXF78257.1 - 4.4e-41 140.7 57.3 1.2e-40 139.3 38.2 2.4 2 1 0 2 2 2 1 Major Facilitator Superfamily Dispanin PF04505.7 EXF78257.1 - 0.03 13.8 2.3 0.19 11.2 0.1 3.3 2 0 0 2 2 2 0 Interferon-induced transmembrane protein F-box PF00646.28 EXF78259.1 - 5.4e-06 25.9 0.1 1.3e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EXF78259.1 - 0.00012 21.7 0.0 0.00023 20.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box-like_2 PF13013.1 EXF78259.1 - 0.0043 16.7 1.6 0.0076 15.9 1.1 1.6 1 1 0 1 1 1 1 F-box-like domain p450 PF00067.17 EXF78260.1 - 9.5e-51 172.7 0.0 1.4e-48 165.6 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 2OG-Fe_Oxy_2 PF10014.4 EXF78264.1 - 0.0024 17.2 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe dioxygenase 2OG-FeII_Oxy_3 PF13640.1 EXF78264.1 - 0.015 15.7 0.0 0.028 14.9 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Aldedh PF00171.17 EXF78265.1 - 3.5e-154 513.5 0.0 4e-154 513.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EXF78265.1 - 0.047 12.9 0.2 0.19 10.9 0.1 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) CVNH PF08881.5 EXF78266.1 - 6.3e-37 125.9 0.3 1.3e-36 124.9 0.2 1.6 1 0 0 1 1 1 1 CVNH domain LysM PF01476.15 EXF78266.1 - 2.9e-13 49.4 0.0 4.6e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 LysM domain Rick_17kDa_Anti PF05433.10 EXF78266.1 - 8.3e-08 31.7 12.6 8.3e-08 31.7 8.7 2.1 2 0 0 2 2 2 1 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.1 EXF78266.1 - 0.00013 21.3 10.3 0.0004 19.8 7.2 1.9 1 0 0 1 1 1 1 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.1 EXF78266.1 - 0.02 14.5 16.2 0.19 11.3 11.1 2.7 1 1 1 2 2 2 0 Glycine zipper DUF533 PF04391.7 EXF78266.1 - 0.023 14.0 0.1 0.051 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF533) Zip PF02535.17 EXF78266.1 - 0.15 11.0 2.3 0.2 10.6 1.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 EXF78266.1 - 2 7.7 7.6 3.1 7.1 5.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region AA_permease PF00324.16 EXF78267.1 - 5.6e-98 328.3 34.9 6.8e-98 328.0 24.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF78267.1 - 2.4e-20 72.4 38.8 3e-20 72.1 26.9 1.1 1 0 0 1 1 1 1 Amino acid permease FAA_hydrolase PF01557.13 EXF78268.1 - 3e-12 46.4 0.0 3.6e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF457 PF04307.9 EXF78270.1 - 3.9 6.7 8.0 1.1 8.6 2.4 2.3 2 1 0 2 2 2 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) zf-MYND PF01753.13 EXF78273.1 - 1.8e-05 24.5 14.6 5.3e-05 22.9 10.1 1.9 1 0 0 1 1 1 1 MYND finger Ribosomal_L10 PF00466.15 EXF78274.1 - 3.5e-05 23.6 0.0 0.00022 21.0 0.0 2.2 1 1 0 1 1 1 1 Ribosomal protein L10 Tic20 PF09685.5 EXF78275.1 - 2.2e-05 24.3 3.4 3.5e-05 23.7 2.4 1.2 1 0 0 1 1 1 1 Tic20-like protein AAA PF00004.24 EXF78276.1 - 8.2e-40 136.0 0.0 1.8e-39 134.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EXF78276.1 - 0.00015 21.7 0.8 0.013 15.5 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EXF78276.1 - 0.0002 21.0 1.4 0.00078 19.1 0.0 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EXF78276.1 - 0.00028 20.0 0.0 0.00064 18.8 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EXF78276.1 - 0.0012 18.9 2.4 0.019 15.1 0.0 3.1 3 1 1 4 4 3 1 AAA domain AAA_2 PF07724.9 EXF78276.1 - 0.0013 18.6 0.3 0.0089 15.9 0.0 2.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) PhoH PF02562.11 EXF78276.1 - 0.0035 16.6 0.3 0.044 12.9 0.1 2.4 2 0 0 2 2 2 1 PhoH-like protein Mg_chelatase PF01078.16 EXF78276.1 - 0.0069 15.5 0.0 0.017 14.3 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EXF78276.1 - 0.0072 15.2 0.0 0.017 14.0 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EXF78276.1 - 0.0093 15.8 0.0 0.025 14.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EXF78276.1 - 0.017 14.8 0.4 0.044 13.5 0.3 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EXF78276.1 - 0.022 14.1 0.1 0.047 13.1 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EXF78276.1 - 0.031 13.6 1.3 0.32 10.3 0.2 2.4 1 1 1 2 2 2 0 AAA domain AAA_24 PF13479.1 EXF78276.1 - 0.044 13.3 0.1 0.14 11.7 0.1 1.9 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EXF78276.1 - 0.086 13.6 0.1 0.086 13.6 0.1 2.8 2 2 0 2 2 2 0 AAA domain Hydrophobin_2 PF06766.6 EXF78277.1 - 4.4e-27 93.5 8.2 5.6e-27 93.2 5.7 1.1 1 0 0 1 1 1 1 Fungal hydrophobin zf-C3Hc3H PF13891.1 EXF78277.1 - 0.096 12.7 2.6 2.5 8.2 0.1 2.2 2 0 0 2 2 2 0 Potential DNA-binding domain Ish1 PF10281.4 EXF78278.1 - 7.7e-81 265.6 25.7 1.7e-12 47.1 0.0 8.5 8 0 0 8 8 8 8 Putative stress-responsive nuclear envelope protein SAP PF02037.22 EXF78278.1 - 1.2e-09 37.4 0.0 0.27 10.7 0.0 7.2 7 1 1 8 8 8 2 SAP domain Slx4 PF09494.5 EXF78278.1 - 3.9e-06 26.5 1.3 14 5.5 0.0 6.2 7 0 0 7 7 7 2 Slx4 endonuclease HeH PF12949.2 EXF78278.1 - 4.8e-05 22.8 0.0 4.5 6.9 0.0 5.3 6 0 0 6 6 6 1 HeH/LEM domain APC2 PF08672.6 EXF78278.1 - 0.0055 16.9 4.5 47 4.3 0.0 6.4 8 0 0 8 8 8 0 Anaphase promoting complex (APC) subunit 2 SAM_2 PF07647.12 EXF78278.1 - 0.069 12.9 1.4 3.5 7.5 0.0 3.5 4 0 0 4 4 4 0 SAM domain (Sterile alpha motif) LEA_4 PF02987.11 EXF78278.1 - 2.5 8.0 17.4 2.3 8.1 0.4 4.8 4 0 0 4 4 4 0 Late embryogenesis abundant protein tRNA_lig_CPD PF08302.6 EXF78279.1 - 2.8e-81 272.5 0.0 4.1e-81 271.9 0.0 1.3 1 0 0 1 1 1 1 Fungal tRNA ligase phosphodiesterase domain RNA_lig_T4_1 PF09511.5 EXF78279.1 - 4.6e-80 268.2 0.0 9.6e-80 267.2 0.0 1.5 1 0 0 1 1 1 1 RNA ligase tRNA_lig_kinase PF08303.6 EXF78279.1 - 7.1e-52 175.6 0.0 1.6e-51 174.5 0.0 1.6 1 0 0 1 1 1 1 tRNA ligase kinase domain AAA_17 PF13207.1 EXF78279.1 - 0.019 15.7 0.0 0.098 13.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EXF78279.1 - 0.035 14.4 0.1 0.14 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Ank_5 PF13857.1 EXF78280.1 - 1.8e-10 40.7 0.1 1.1e-08 35.0 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EXF78280.1 - 6.3e-08 32.9 0.0 0.00013 22.3 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EXF78280.1 - 1.5e-05 25.2 0.7 0.00027 21.2 0.5 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EXF78280.1 - 2.4e-05 23.9 0.4 0.0068 16.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EXF78280.1 - 0.00014 21.7 0.5 0.0044 17.1 0.2 2.8 2 0 0 2 2 2 1 Ankyrin repeat VP9 PF09625.5 EXF78280.1 - 0.098 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 VP9 protein Ribonuc_P_40 PF08584.6 EXF78281.1 - 9.6e-69 231.5 0.0 1.2e-68 231.1 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit UPF0020 PF01170.13 EXF78282.1 - 1.5e-12 47.4 0.0 2.4e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EXF78282.1 - 6.1e-09 35.9 0.0 1.4e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Vac_ImportDeg PF09783.4 EXF78283.1 - 8.6e-71 237.0 0.7 1.2e-70 236.6 0.5 1.1 1 0 0 1 1 1 1 Vacuolar import and degradation protein Mago_nashi PF02792.9 EXF78285.1 - 4.6e-75 250.0 0.3 5.4e-75 249.8 0.2 1.0 1 0 0 1 1 1 1 Mago nashi protein Phage_portal_2 PF05136.8 EXF78285.1 - 0.023 13.2 0.0 0.028 12.9 0.0 1.0 1 0 0 1 1 1 0 Phage portal protein, lambda family Adaptin_N PF01602.15 EXF78286.1 - 4.3e-96 322.3 11.7 4.3e-96 322.3 8.1 1.5 2 0 0 2 2 2 1 Adaptin N terminal region Coatamer_beta_C PF07718.7 EXF78286.1 - 3.8e-63 211.3 0.9 8.2e-63 210.2 0.6 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.1 EXF78286.1 - 4.4e-63 210.7 0.0 1.6e-62 208.9 0.0 2.0 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.1 EXF78286.1 - 7.3e-13 48.6 5.4 1.3e-07 31.8 0.0 4.0 1 1 2 3 3 3 3 HEAT repeats Cnd1 PF12717.2 EXF78286.1 - 0.00015 21.6 10.4 0.0043 16.9 0.1 4.1 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EXF78286.1 - 0.00077 19.3 1.0 1.1 9.5 0.0 4.6 5 0 0 5 5 5 1 HEAT repeat AP4E_app_platf PF14807.1 EXF78286.1 - 0.026 14.7 0.1 0.12 12.5 0.1 2.2 1 0 0 1 1 1 0 Adaptin AP4 complex epsilon appendage platform HEAT_EZ PF13513.1 EXF78286.1 - 0.044 14.2 4.3 4.2 7.9 0.0 4.7 4 1 1 5 5 5 0 HEAT-like repeat RE_Alw26IDE PF09665.5 EXF78286.1 - 8.1 5.0 10.6 0.78 8.3 0.5 3.2 3 1 1 4 4 4 0 Type II restriction endonuclease (RE_Alw26IDE) ubiquitin PF00240.18 EXF78287.1 - 5.9e-08 32.0 0.0 1.1e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407 PF10302.4 EXF78287.1 - 0.00089 19.4 0.6 0.002 18.2 0.0 1.8 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Rad60-SLD PF11976.3 EXF78287.1 - 0.0023 17.5 0.0 0.0046 16.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EXF78287.1 - 0.02 14.7 0.1 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF4141 PF13605.1 EXF78287.1 - 0.12 11.6 0.1 1.8 7.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4141) Glyco_hydro_7 PF00840.15 EXF78288.1 - 3.3e-146 487.0 8.1 4.8e-146 486.5 5.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 SET PF00856.23 EXF78288.1 - 2.8e-21 76.5 0.0 5.2e-20 72.3 0.0 2.5 2 1 0 2 2 2 1 SET domain Pre-SET PF05033.11 EXF78288.1 - 1.1e-19 70.6 4.9 1.1e-19 70.6 3.4 2.9 4 0 0 4 4 4 1 Pre-SET motif HET PF06985.6 EXF78289.1 - 3.6e-14 53.0 0.7 3.6e-14 53.0 0.5 2.2 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) HET PF06985.6 EXF78291.1 - 4.3e-15 56.0 1.5 7.8e-15 55.2 1.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF336 PF03928.9 EXF78292.1 - 9.5e-18 64.2 0.0 9.5e-18 64.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF336) SnoaL_4 PF13577.1 EXF78293.1 - 3.3e-20 72.3 1.4 3.9e-20 72.0 1.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain Lumazine_bd_2 PF12893.2 EXF78293.1 - 2.5e-07 31.2 0.0 3.7e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Putative lumazine-binding CFEM PF05730.6 EXF78295.1 - 0.0012 18.5 2.8 0.0021 17.8 1.9 1.4 1 0 0 1 1 1 1 CFEM domain Ank_2 PF12796.2 EXF78296.1 - 6.3e-77 253.9 6.4 2.8e-18 66.0 0.0 6.3 2 2 5 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EXF78296.1 - 6.4e-43 142.4 5.6 3.9e-06 26.4 0.0 11.4 12 0 0 12 12 12 10 Ankyrin repeat Ank_4 PF13637.1 EXF78296.1 - 2.7e-41 139.2 0.5 6.2e-09 36.1 0.0 9.5 6 3 5 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF78296.1 - 3.8e-41 134.9 0.6 4.9e-06 26.2 0.0 10.8 11 0 0 11 11 11 8 Ankyrin repeat Ank_5 PF13857.1 EXF78296.1 - 6.5e-31 105.6 0.6 1.1e-05 25.5 0.0 7.6 3 2 6 9 9 9 8 Ankyrin repeats (many copies) DUF1843 PF08898.5 EXF78296.1 - 0.094 12.7 0.0 11 6.1 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) NmrA PF05368.8 EXF78297.1 - 7e-21 74.5 0.1 9.3e-21 74.1 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF78297.1 - 1.4e-09 38.1 0.0 2.1e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EXF78297.1 - 2e-05 23.7 0.0 2.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EXF78297.1 - 0.00082 18.8 0.0 0.0019 17.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EXF78297.1 - 0.0018 18.5 0.2 0.0038 17.5 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EXF78297.1 - 0.0026 17.6 0.0 0.0052 16.7 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 EXF78297.1 - 0.015 14.0 0.0 0.061 12.0 0.0 1.9 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EXF78297.1 - 0.023 13.6 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein p450 PF00067.17 EXF78298.1 - 1.2e-56 192.2 0.1 1.5e-56 191.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3149 PF11346.3 EXF78298.1 - 0.96 9.0 3.2 6.9 6.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3149) Asn_synthase PF00733.16 EXF78299.1 - 2.7e-53 181.0 0.0 4.3e-53 180.4 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EXF78299.1 - 4.1e-35 120.2 0.0 1.4e-34 118.5 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EXF78299.1 - 6.5e-33 113.5 0.0 1.6e-32 112.2 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EXF78299.1 - 1.7e-06 27.4 0.0 3.5e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein tRNA_Me_trans PF03054.11 EXF78299.1 - 0.0024 16.4 0.0 0.0039 15.8 0.0 1.3 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.12 EXF78299.1 - 0.023 13.6 0.0 0.04 12.8 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Raftlin PF15250.1 EXF78300.1 - 0.012 14.1 11.0 0.015 13.8 7.6 1.0 1 0 0 1 1 1 0 Raftlin PPP4R2 PF09184.6 EXF78300.1 - 3.5 7.1 21.9 4 6.9 15.2 1.1 1 0 0 1 1 1 0 PPP4R2 DUF1510 PF07423.6 EXF78300.1 - 5.2 6.3 27.9 7.7 5.8 19.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) MFS_1 PF07690.11 EXF78301.1 - 2.8e-15 55.8 45.0 3.6e-14 52.2 30.2 2.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Abhydrolase_4 PF08386.5 EXF78303.1 - 5.5e-21 74.3 0.2 2.4e-20 72.3 0.0 2.0 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 EXF78303.1 - 1.4e-11 44.3 0.0 1.8e-09 37.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EXF78303.1 - 3.9e-05 23.6 0.0 0.00049 20.0 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF78303.1 - 0.0044 16.7 0.0 2.7 7.7 0.0 2.3 2 1 0 2 2 2 2 Alpha/beta hydrolase family Asp PF00026.18 EXF78304.1 - 2e-09 37.1 0.0 3.9e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease SKG6 PF08693.5 EXF78304.1 - 0.068 12.4 2.5 0.18 11.1 1.7 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain GRIM-19 PF06212.7 EXF78306.1 - 0.097 12.3 0.1 0.12 12.1 0.1 1.1 1 0 0 1 1 1 0 GRIM-19 protein AA_permease_2 PF13520.1 EXF78307.1 - 2.5e-73 247.0 30.6 3.1e-73 246.7 21.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF78307.1 - 3e-23 81.9 28.9 3.7e-23 81.6 20.0 1.0 1 0 0 1 1 1 1 Amino acid permease TauD PF02668.11 EXF78308.1 - 4.2e-14 52.8 0.0 3.8e-10 39.8 0.0 2.6 1 1 0 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family RhoGAP PF00620.22 EXF78308.1 - 0.025 14.1 0.0 0.042 13.4 0.0 1.4 1 0 0 1 1 1 0 RhoGAP domain MFS_1 PF07690.11 EXF78309.1 - 4.3e-23 81.6 17.1 2.6e-17 62.6 5.2 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily 2-Hacid_dh_C PF02826.14 EXF78310.1 - 4e-45 153.1 0.1 5.6e-45 152.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EXF78310.1 - 4.8e-12 45.5 0.0 6.7e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EXF78310.1 - 1.9e-05 24.5 0.0 3.2e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 EXF78310.1 - 0.0031 18.0 0.0 0.0062 17.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Glyco_hydro_43 PF04616.9 EXF78311.1 - 2e-77 260.0 0.1 2.8e-77 259.6 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 p450 PF00067.17 EXF78311.1 - 1.4e-28 99.6 0.0 2e-28 99.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydrolase_3 PF07859.8 EXF78312.1 - 1.4e-22 80.2 0.3 3.3e-19 69.3 0.2 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF78312.1 - 6.8e-12 45.3 0.0 1.3e-11 44.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF78312.1 - 6.4e-11 42.5 2.2 8.4e-11 42.1 1.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF78312.1 - 9.2e-09 34.8 0.0 0.00015 21.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 EXF78312.1 - 3.1e-06 26.2 0.0 4.6e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.6 EXF78312.1 - 0.00033 19.5 0.1 0.00056 18.8 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_2 PF02230.11 EXF78312.1 - 0.019 14.4 0.0 0.77 9.1 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_4 PF08386.5 EXF78312.1 - 0.079 12.8 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 TAP-like protein DLH PF01738.13 EXF78312.1 - 0.089 12.0 0.0 0.69 9.1 0.0 2.2 2 1 0 2 2 2 0 Dienelactone hydrolase family COesterase PF00135.23 EXF78312.1 - 0.13 10.9 0.0 0.21 10.2 0.0 1.3 1 0 0 1 1 1 0 Carboxylesterase family p450 PF00067.17 EXF78313.1 - 5.5e-59 199.8 0.0 7.7e-59 199.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EXF78314.1 - 1.2e-09 38.3 0.1 1.4e-09 38.1 0.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF78314.1 - 3.8e-05 23.5 0.0 4.5e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF78314.1 - 6.6e-05 22.6 0.1 7.9e-05 22.3 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EXF78314.1 - 0.14 12.1 2.1 0.93 9.4 1.5 1.9 1 1 1 2 2 2 0 NADH(P)-binding 4HBT_2 PF13279.1 EXF78315.1 - 1.3e-10 41.7 0.0 2.1e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase-like superfamily DBR1 PF05011.8 EXF78315.1 - 0.00096 19.0 0.0 0.0014 18.4 0.0 1.2 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain 4HBT PF03061.17 EXF78315.1 - 0.021 14.9 0.0 0.042 13.9 0.0 1.5 1 0 0 1 1 1 0 Thioesterase superfamily His_Phos_2 PF00328.17 EXF78316.1 - 3.3e-23 82.5 0.0 4.3e-23 82.1 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EXF78316.1 - 0.019 15.0 0.0 0.029 14.4 0.0 1.3 1 0 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) NAD_binding_8 PF13450.1 EXF78317.1 - 0.00068 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EXF78317.1 - 0.0018 17.3 0.0 0.01 14.8 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EXF78317.1 - 0.05 12.5 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EXF78317.1 - 0.094 11.3 0.0 0.14 10.7 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase DAO PF01266.19 EXF78317.1 - 0.095 11.5 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF78317.1 - 0.12 12.2 0.0 0.21 11.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AA_permease_2 PF13520.1 EXF78318.1 - 2.9e-62 210.5 46.2 3.6e-62 210.2 32.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF78318.1 - 3.1e-12 45.6 41.9 4.2e-12 45.1 29.0 1.1 1 0 0 1 1 1 1 Amino acid permease UPF0560 PF10577.4 EXF78319.1 - 0.0046 15.2 0.4 0.005 15.1 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0560 PHO4 PF01384.15 EXF78321.1 - 1e-108 362.8 9.6 1.2e-108 362.6 6.7 1.0 1 0 0 1 1 1 1 Phosphate transporter family Glycophorin_A PF01102.13 EXF78321.1 - 0.0073 16.0 0.1 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Glycophorin A FAD_binding_3 PF01494.14 EXF78322.1 - 5.1e-06 25.7 0.0 7.2e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain IGPS PF00218.16 EXF78322.1 - 0.081 11.9 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase LysM PF01476.15 EXF78325.1 - 3.2e-12 46.1 0.0 2.4e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 LysM domain Glyco_hydro_18 PF00704.23 EXF78326.1 - 2.3e-77 260.7 6.2 4.2e-77 259.9 2.9 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EXF78326.1 - 1.7e-08 34.2 6.1 1.7e-08 34.2 4.2 3.6 5 1 0 5 5 5 1 Chitin recognition protein Reo_sigmaC PF04582.7 EXF78328.1 - 2.5e-07 30.2 22.6 0.0054 15.9 0.0 4.6 2 1 1 4 4 4 3 Reovirus sigma C capsid protein APG6 PF04111.7 EXF78328.1 - 1.5e-05 24.2 12.7 1.5e-05 24.2 8.8 5.2 3 2 2 5 5 5 2 Autophagy protein Apg6 Spc7 PF08317.6 EXF78328.1 - 3e-05 22.8 9.5 3e-05 22.8 6.6 4.6 2 1 2 4 4 4 3 Spc7 kinetochore protein Myosin_tail_1 PF01576.14 EXF78328.1 - 4.4e-05 21.4 75.3 4.4e-05 21.4 52.2 2.3 2 0 0 2 2 2 1 Myosin tail IncA PF04156.9 EXF78328.1 - 5.5e-05 22.8 6.1 5.5e-05 22.8 4.2 6.9 2 2 4 6 6 6 3 IncA protein GAS PF13851.1 EXF78328.1 - 0.00014 21.1 65.1 0.0046 16.1 5.6 4.8 2 1 1 4 4 4 2 Growth-arrest specific micro-tubule binding AAA_13 PF13166.1 EXF78328.1 - 0.0014 17.1 13.4 0.0014 17.1 9.3 4.1 2 1 1 4 4 4 2 AAA domain CENP-F_leu_zip PF10473.4 EXF78328.1 - 0.0038 17.0 14.5 0.0038 17.0 10.0 7.8 2 2 4 6 6 6 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.13 EXF78328.1 - 0.0049 16.5 39.4 0.16 11.7 0.5 10.3 8 3 2 11 11 11 2 Homeobox associated leucine zipper ERM PF00769.14 EXF78328.1 - 0.0049 16.4 6.9 0.0049 16.4 4.8 5.3 2 1 1 4 4 3 2 Ezrin/radixin/moesin family ADIP PF11559.3 EXF78328.1 - 0.014 15.2 1.5 0.014 15.2 1.1 8.0 3 3 5 8 8 8 0 Afadin- and alpha -actinin-Binding TSC22 PF01166.13 EXF78328.1 - 0.03 14.2 0.5 0.03 14.2 0.4 8.4 8 4 3 11 11 11 0 TSC-22/dip/bun family DUF869 PF05911.6 EXF78328.1 - 7.4 4.6 69.3 0.65 8.1 16.2 3.9 2 1 1 3 3 3 0 Plant protein of unknown function (DUF869) CFEM PF05730.6 EXF78329.1 - 7.8e-12 44.8 11.0 7.8e-12 44.8 7.7 1.9 2 1 0 2 2 2 1 CFEM domain Gamma-thionin PF00304.15 EXF78329.1 - 0.034 14.1 0.7 0.059 13.3 0.5 1.3 1 0 0 1 1 1 0 Gamma-thionin family FmdE PF02663.9 EXF78329.1 - 0.65 9.8 2.5 0.8 9.5 1.0 1.7 1 1 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Rifin_STEVOR PF02009.11 EXF78329.1 - 3.1 7.3 7.3 3.5 7.1 5.0 1.3 1 0 0 1 1 1 0 Rifin/stevor family Cupin_1 PF00190.17 EXF78331.1 - 6.7e-32 109.9 0.0 4.4e-16 58.6 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EXF78331.1 - 7.2e-26 89.4 0.7 2.3e-13 49.4 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EXF78331.1 - 7.5e-08 31.6 0.0 0.015 14.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EXF78331.1 - 1.3e-07 31.3 0.2 0.0004 20.0 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.13 EXF78331.1 - 0.00022 20.8 0.0 0.048 13.2 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase ARD PF03079.9 EXF78331.1 - 0.00085 19.3 0.3 0.044 13.7 0.0 2.4 2 0 0 2 2 2 1 ARD/ARD' family FdtA PF05523.6 EXF78331.1 - 0.0047 16.4 0.0 0.63 9.5 0.0 2.2 2 0 0 2 2 2 1 WxcM-like, C-terminal GPI PF06560.6 EXF78331.1 - 0.0097 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) 3-HAO PF06052.7 EXF78331.1 - 0.07 12.5 0.0 0.47 9.8 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase Sulfate_transp PF00916.15 EXF78332.1 - 2.3e-55 187.5 9.6 4.8e-55 186.5 6.6 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EXF78332.1 - 4.7e-28 96.6 2.6 4.7e-28 96.6 1.8 3.5 3 1 1 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EXF78332.1 - 1.2e-12 47.2 0.0 2.2e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain bZIP_1 PF00170.16 EXF78333.1 - 0.32 10.9 5.9 0.62 10.0 0.1 2.8 3 0 0 3 3 3 0 bZIP transcription factor Atg14 PF10186.4 EXF78333.1 - 0.79 8.6 15.0 14 4.5 10.1 2.0 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF904 PF06005.7 EXF78333.1 - 1.1 9.6 9.2 1.2 9.4 4.2 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF904) SOBP PF15279.1 EXF78333.1 - 1.3 9.3 7.0 1.6 9.0 4.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein AKNA PF12443.3 EXF78333.1 - 3.1 7.8 12.8 1.8 8.5 0.8 2.6 2 2 0 2 2 2 0 AT-hook-containing transcription factor Pox_P35 PF03213.9 EXF78334.1 - 0.067 12.1 0.4 0.084 11.8 0.2 1.1 1 0 0 1 1 1 0 Poxvirus P35 protein Enkurin PF13864.1 EXF78334.1 - 0.11 12.6 5.6 2.2 8.5 0.7 2.2 1 1 1 2 2 2 0 Calmodulin-binding Kinetocho_Slk19 PF12709.2 EXF78334.1 - 0.14 12.2 3.3 0.54 10.3 0.2 2.2 2 1 0 2 2 2 0 Central kinetochore-associated DUF3391 PF11871.3 EXF78334.1 - 0.17 12.0 1.1 0.23 11.6 0.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) BBP1_C PF15272.1 EXF78334.1 - 0.31 10.5 5.1 0.4 10.2 3.5 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal AIP3 PF03915.8 EXF78334.1 - 0.47 9.3 5.6 0.52 9.1 3.9 1.0 1 0 0 1 1 1 0 Actin interacting protein 3 AAA_13 PF13166.1 EXF78334.1 - 0.5 8.7 6.9 0.55 8.6 4.8 1.0 1 0 0 1 1 1 0 AAA domain KfrA_N PF11740.3 EXF78334.1 - 0.61 10.5 4.1 0.87 10.0 2.8 1.4 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term TMF_DNA_bd PF12329.3 EXF78334.1 - 1.4 8.7 6.7 0.49 10.2 1.1 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF4618 PF15397.1 EXF78334.1 - 1.7 7.8 6.8 5.8 6.1 0.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) DUF4200 PF13863.1 EXF78334.1 - 2.1 8.3 8.5 12 5.8 5.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) CENP-H PF05837.7 EXF78334.1 - 3.2 7.9 6.9 8.2 6.6 4.4 1.8 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF4527 PF15030.1 EXF78335.1 - 8.6e-05 21.9 2.5 8.6e-05 21.9 1.8 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4527) R3H-assoc PF13902.1 EXF78335.1 - 0.0087 16.0 0.1 0.0087 16.0 0.1 1.9 2 1 0 2 2 2 1 R3H-associated N-terminal domain DivIC PF04977.10 EXF78335.1 - 0.023 14.1 9.3 0.023 14.1 6.4 2.6 2 1 1 3 3 3 0 Septum formation initiator Cas_Cas6 PF01881.11 EXF78335.1 - 0.031 14.5 0.5 0.031 14.5 0.3 2.0 1 1 1 2 2 2 0 CRISPR associated protein Cas6 PEARLI-4 PF05278.7 EXF78335.1 - 0.8 9.0 9.7 0.12 11.6 3.5 1.9 1 1 1 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) Syntaxin-6_N PF09177.6 EXF78335.1 - 1.6 9.2 8.3 0.25 11.7 1.7 2.6 1 1 2 3 3 3 0 Syntaxin 6, N-terminal MIT PF04212.13 EXF78335.1 - 2.5 8.0 10.3 0.25 11.2 0.6 2.8 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Atg14 PF10186.4 EXF78335.1 - 7.2 5.4 22.5 4.9 6.0 9.0 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4381 PF14316.1 EXF78335.1 - 8.3 6.5 7.8 47 4.0 3.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4381) AAA_23 PF13476.1 EXF78335.1 - 8.7 6.6 17.2 16 5.7 11.9 1.4 1 1 0 1 1 1 0 AAA domain Nop52 PF05997.7 EXF78336.1 - 5.8e-51 172.9 0.2 7.3e-51 172.6 0.1 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 HEAT_2 PF13646.1 EXF78336.1 - 0.064 13.5 0.4 1.8 8.9 0.0 2.7 3 0 0 3 3 3 0 HEAT repeats DUF416 PF04222.7 EXF78336.1 - 0.083 12.0 1.5 0.09 11.9 0.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF416) DAGK_cat PF00781.19 EXF78337.1 - 3.6e-24 84.6 0.0 6.7e-24 83.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PRKCSH-like PF12999.2 EXF78337.1 - 0.023 14.2 0.0 0.039 13.5 0.0 1.3 1 0 0 1 1 1 0 Glucosidase II beta subunit-like Glycos_transf_3 PF00591.16 EXF78338.1 - 9.5e-65 218.5 0.0 1.4e-64 217.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.12 EXF78338.1 - 1.2e-07 31.1 0.2 4e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family, helical bundle domain NARP1 PF12569.3 EXF78339.1 - 3.4e-193 643.1 26.1 1.5e-191 637.7 14.4 2.3 2 0 0 2 2 2 2 NMDA receptor-regulated protein 1 Cid2 PF09774.4 EXF78339.1 - 3.2e-46 157.1 0.0 3.2e-46 157.1 0.0 2.3 2 0 0 2 2 1 1 Caffeine-induced death protein 2 TPR_19 PF14559.1 EXF78339.1 - 9.6e-21 73.9 25.1 2.9e-05 24.3 3.2 7.6 7 2 1 8 8 7 5 Tetratricopeptide repeat TPR_16 PF13432.1 EXF78339.1 - 1.4e-14 54.3 42.2 0.0021 18.6 0.1 10.3 8 2 2 11 11 10 5 Tetratricopeptide repeat TPR_11 PF13414.1 EXF78339.1 - 2.3e-14 52.8 27.2 6.1e-05 22.5 0.3 7.0 7 1 1 8 8 8 5 TPR repeat TPR_14 PF13428.1 EXF78339.1 - 1.3e-09 37.7 30.6 0.0037 17.7 0.0 11.1 9 3 5 14 14 10 3 Tetratricopeptide repeat TPR_2 PF07719.12 EXF78339.1 - 4.9e-09 35.4 42.4 0.00023 20.8 0.2 10.5 12 0 0 12 12 11 3 Tetratricopeptide repeat Apc3 PF12895.2 EXF78339.1 - 6.5e-09 35.8 15.7 1.8e-05 24.7 0.9 5.4 4 2 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EXF78339.1 - 4.9e-08 32.7 12.5 0.00028 20.6 0.2 6.6 7 1 1 8 8 8 2 Tetratricopeptide repeat TPR_12 PF13424.1 EXF78339.1 - 5.7e-08 32.5 32.5 0.017 15.0 0.1 8.9 7 2 3 10 10 10 3 Tetratricopeptide repeat TPR_1 PF00515.23 EXF78339.1 - 9.6e-08 31.3 19.4 2.6e-05 23.6 0.4 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.1 EXF78339.1 - 3.1e-07 30.0 11.2 0.79 10.0 0.0 8.0 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 EXF78339.1 - 1.3e-06 27.7 7.0 0.0059 16.3 0.1 6.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_3 PF07720.7 EXF78339.1 - 0.0071 16.1 1.4 0.23 11.3 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EXF78339.1 - 0.009 15.7 9.4 6.1 6.8 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EXF78339.1 - 0.33 11.5 24.7 4.2 8.0 0.1 8.5 10 0 0 10 10 7 0 Tetratricopeptide repeat TPR_4 PF07721.9 EXF78339.1 - 0.5 10.9 9.4 13 6.5 0.1 5.8 7 0 0 7 7 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EXF78339.1 - 0.64 9.9 11.8 13 5.7 0.1 5.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Sel1 PF08238.7 EXF78339.1 - 1.3 9.7 5.5 8.6 7.1 0.0 3.5 3 0 0 3 3 2 0 Sel1 repeat TPR_10 PF13374.1 EXF78339.1 - 2.3 8.2 14.4 11 6.0 0.1 6.5 9 0 0 9 9 8 0 Tetratricopeptide repeat Ank_2 PF12796.2 EXF78340.1 - 3.8e-81 267.5 2.2 3e-15 56.3 0.0 7.4 4 1 4 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 EXF78340.1 - 1.4e-68 223.4 15.8 6.1e-07 28.9 0.2 14.3 14 0 0 14 14 14 13 Ankyrin repeat Ank_3 PF13606.1 EXF78340.1 - 6.9e-54 174.4 11.3 8.1e-05 22.5 0.0 13.8 14 0 0 14 14 14 11 Ankyrin repeat Ank_4 PF13637.1 EXF78340.1 - 4e-50 167.3 7.1 1.5e-08 34.9 0.0 10.6 4 2 7 11 11 11 11 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF78340.1 - 6.8e-46 153.2 13.1 3.4e-09 36.6 0.0 9.9 5 2 6 11 11 11 9 Ankyrin repeats (many copies) DUF1688 PF07958.6 EXF78342.1 - 5.6e-166 552.2 0.0 6.4e-166 552.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) DUF2419 PF10343.4 EXF78342.1 - 0.0017 17.7 0.0 0.066 12.4 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF2419) HET PF06985.6 EXF78343.1 - 3.1e-20 72.7 0.0 9.6e-20 71.1 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_hydro_43 PF04616.9 EXF78344.1 - 6.1e-73 245.3 2.1 8e-73 245.0 1.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 EXF78344.1 - 0.06 12.6 1.2 0.092 12.0 0.0 1.8 2 0 0 2 2 2 0 Glycosyl hydrolases family 32 N-terminal domain Zn_clus PF00172.13 EXF78345.1 - 0.01 15.7 5.4 0.017 15.0 3.8 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Glutaminase PF04960.10 EXF78346.1 - 2.9e-99 331.6 0.3 3.6e-99 331.3 0.2 1.1 1 0 0 1 1 1 1 Glutaminase 2-Hacid_dh_C PF02826.14 EXF78347.1 - 3.2e-56 189.3 0.0 4.3e-56 188.8 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EXF78347.1 - 4.5e-13 48.8 0.0 6.1e-13 48.3 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EXF78347.1 - 4.1e-07 29.9 0.0 7.4e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EXF78347.1 - 0.0011 19.3 0.0 0.0029 17.9 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.7 EXF78347.1 - 0.0083 15.5 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain AdoHcyase PF05221.12 EXF78348.1 - 4.7e-139 461.8 0.2 5.6e-139 461.5 0.1 1.1 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EXF78348.1 - 1.1e-83 278.9 2.2 1.8e-83 278.2 1.5 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EXF78348.1 - 3.5e-06 26.3 1.7 6e-06 25.5 0.1 2.2 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EXF78348.1 - 0.0011 18.5 0.1 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.13 EXF78348.1 - 0.005 16.8 0.0 0.011 15.7 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain IlvN PF07991.7 EXF78348.1 - 0.0085 15.4 0.2 0.016 14.5 0.1 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain adh_short PF00106.20 EXF78348.1 - 0.024 14.5 0.7 6.7 6.5 0.0 2.6 2 0 0 2 2 2 0 short chain dehydrogenase 3HCDH_N PF02737.13 EXF78348.1 - 0.051 13.2 0.2 0.1 12.2 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain JAB PF01398.16 EXF78349.1 - 9.2e-09 35.0 0.9 2.6e-07 30.3 0.6 2.3 1 1 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease GDE_N PF12439.3 EXF78349.1 - 0.061 12.5 1.3 2.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Glycogen debranching enzyme N terminal Mito_carr PF00153.22 EXF78351.1 - 2.3e-51 171.4 4.1 2.3e-20 72.0 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein GATase PF00117.23 EXF78352.1 - 1.7e-36 125.4 0.0 6.3e-36 123.6 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I GMP_synt_C PF00958.17 EXF78352.1 - 4.7e-33 112.7 0.0 1.1e-32 111.5 0.0 1.6 2 0 0 2 2 2 1 GMP synthase C terminal domain NAD_synthase PF02540.12 EXF78352.1 - 1.9e-08 33.5 0.0 8.3e-06 24.8 0.0 2.2 2 0 0 2 2 2 2 NAD synthase Peptidase_C26 PF07722.8 EXF78352.1 - 5.9e-07 29.1 0.0 1.5e-06 27.8 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 tRNA_Me_trans PF03054.11 EXF78352.1 - 0.0039 15.8 0.1 0.0092 14.5 0.0 1.6 2 0 0 2 2 2 1 tRNA methyl transferase QueC PF06508.8 EXF78352.1 - 0.0042 16.3 0.0 0.14 11.4 0.0 2.2 2 0 0 2 2 2 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.16 EXF78352.1 - 0.0093 15.4 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase ThiI PF02568.9 EXF78352.1 - 0.015 14.7 0.0 0.033 13.6 0.0 1.6 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.14 EXF78352.1 - 0.026 14.3 0.0 0.042 13.6 0.0 1.3 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family DUF2392 PF10288.4 EXF78352.1 - 0.047 14.0 0.0 0.11 12.8 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2392) ATP_bind_3 PF01171.15 EXF78352.1 - 0.083 12.3 0.0 0.26 10.7 0.0 1.9 3 0 0 3 3 3 0 PP-loop family NO_synthase PF02898.10 EXF78353.1 - 7.1e-75 251.9 0.0 1.4e-73 247.7 0.0 2.1 2 0 0 2 2 2 1 Nitric oxide synthase, oxygenase domain Flavodoxin_1 PF00258.20 EXF78353.1 - 2.7e-09 37.1 0.0 1.1e-08 35.1 0.0 2.1 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 EXF78353.1 - 5.3e-06 26.0 0.0 0.00046 19.6 0.0 2.2 1 1 1 2 2 2 2 FAD binding domain NAD_binding_1 PF00175.16 EXF78353.1 - 0.00022 21.7 0.0 0.00058 20.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain ChAPs PF09295.5 EXF78355.1 - 5.7e-159 529.1 0.0 7.1e-159 528.7 0.0 1.1 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.1 EXF78355.1 - 1.5e-07 31.4 0.8 0.29 11.8 0.2 4.8 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EXF78355.1 - 1.5e-05 24.5 0.3 0.17 11.5 0.0 3.3 3 0 0 3 3 3 2 TPR repeat TPR_7 PF13176.1 EXF78355.1 - 3.6e-05 23.2 0.5 0.41 10.5 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EXF78355.1 - 4.3e-05 23.1 0.6 0.053 13.4 0.4 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EXF78355.1 - 0.00033 20.9 0.0 0.43 10.9 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EXF78355.1 - 0.00038 20.2 0.7 0.25 11.2 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EXF78355.1 - 0.00044 19.8 0.1 1.1 9.1 0.1 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EXF78355.1 - 0.0049 16.4 0.3 3.1 7.5 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 EXF78355.1 - 0.0075 16.3 0.1 5 7.3 0.0 3.1 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EXF78355.1 - 0.0078 16.6 0.1 30 5.3 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EXF78355.1 - 0.032 14.9 3.4 11 6.8 0.5 3.7 2 1 2 4 4 4 0 Tetratricopeptide repeat DUF2007 PF09413.5 EXF78355.1 - 0.089 12.6 0.0 0.26 11.1 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF2007) TPR_12 PF13424.1 EXF78355.1 - 0.15 11.9 2.6 4.3 7.3 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 EXF78356.1 - 0.012 15.7 0.1 16 6.0 0.0 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EXF78356.1 - 0.017 14.7 10.2 0.67 9.6 0.3 5.2 5 1 0 5 5 5 0 TPR repeat TPR_14 PF13428.1 EXF78356.1 - 1.4 9.7 17.6 4.8 8.1 0.1 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat DSS1_SEM1 PF05160.8 EXF78357.1 - 1.2e-24 85.8 11.9 1.4e-24 85.6 8.0 1.3 1 1 0 1 1 1 1 DSS1/SEM1 family Cwf_Cwc_15 PF04889.7 EXF78357.1 - 0.59 9.8 8.8 0.69 9.5 6.1 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PGK PF00162.14 EXF78358.1 - 6.2e-153 508.9 1.1 7e-153 508.7 0.8 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Mpv17_PMP22 PF04117.7 EXF78359.1 - 1.5e-22 78.9 2.0 1.1e-21 76.1 0.2 2.4 2 1 0 2 2 2 1 Mpv17 / PMP22 family Glyco_hydro_53 PF07745.8 EXF78360.1 - 4.2e-81 272.2 0.0 5.1e-81 272.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 53 DIM PF08194.7 EXF78360.1 - 0.16 11.9 0.4 0.33 10.9 0.2 1.5 1 0 0 1 1 1 0 DIM protein CwfJ_C_1 PF04677.10 EXF78361.1 - 1.6e-26 92.3 0.0 2.7e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EXF78361.1 - 5.1e-22 78.1 0.0 2.3e-21 76.1 0.0 2.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 MFP2b PF12150.3 EXF78361.1 - 0.072 11.7 0.1 0.65 8.6 0.0 2.1 2 0 0 2 2 2 0 Cytosolic motility protein CHAT PF12770.2 EXF78361.1 - 0.12 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 CHAT domain ATP_bind_1 PF03029.12 EXF78362.1 - 1.4e-76 257.1 0.0 1.8e-76 256.8 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EXF78362.1 - 2.9e-05 23.5 0.1 0.0014 18.0 0.0 2.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EXF78362.1 - 3.3e-05 23.8 0.0 8.7e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EXF78362.1 - 8.3e-05 23.3 1.2 0.00063 20.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain Miro PF08477.8 EXF78362.1 - 0.00012 22.4 0.0 0.67 10.4 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein AAA_22 PF13401.1 EXF78362.1 - 0.00014 21.9 0.0 0.0006 19.9 0.0 2.0 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EXF78362.1 - 0.00025 20.2 0.0 0.00053 19.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 EXF78362.1 - 0.00068 19.6 0.0 0.0014 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ArgK PF03308.11 EXF78362.1 - 0.0011 17.8 0.1 0.24 10.1 0.0 2.5 2 1 0 2 2 2 1 ArgK protein AAA_30 PF13604.1 EXF78362.1 - 0.0013 18.3 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EXF78362.1 - 0.0017 18.0 0.0 0.0031 17.1 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_33 PF13671.1 EXF78362.1 - 0.0024 17.7 0.0 0.0083 16.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EXF78362.1 - 0.0032 16.9 0.6 0.0059 16.0 0.4 1.7 1 1 0 1 1 1 1 AAA-like domain cobW PF02492.14 EXF78362.1 - 0.0034 16.8 0.0 0.12 11.7 0.0 2.4 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PRK PF00485.13 EXF78362.1 - 0.0038 16.8 0.0 0.0083 15.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.17 EXF78362.1 - 0.004 16.6 0.0 0.021 14.2 0.0 2.1 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain MobB PF03205.9 EXF78362.1 - 0.0042 16.7 0.0 0.0084 15.8 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.17 EXF78362.1 - 0.0057 15.5 0.1 0.012 14.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain FeoB_N PF02421.13 EXF78362.1 - 0.0059 15.9 0.0 0.092 12.0 0.0 2.4 2 1 0 2 2 2 1 Ferrous iron transport protein B G-alpha PF00503.15 EXF78362.1 - 0.0066 15.1 0.0 0.41 9.2 0.0 2.4 3 0 0 3 3 3 1 G-protein alpha subunit Arf PF00025.16 EXF78362.1 - 0.013 14.7 0.0 2.6 7.2 0.0 2.4 2 0 0 2 2 2 0 ADP-ribosylation factor family Ras PF00071.17 EXF78362.1 - 0.016 14.5 0.0 1.5 8.1 0.0 2.7 2 1 0 2 2 2 0 Ras family AAA_24 PF13479.1 EXF78362.1 - 0.019 14.5 0.0 0.043 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EXF78362.1 - 0.023 14.3 0.0 0.086 12.5 0.0 1.8 2 0 0 2 2 2 0 Archaeal ATPase AAA_14 PF13173.1 EXF78362.1 - 0.037 13.9 0.0 0.087 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EXF78362.1 - 0.039 13.7 0.1 1.2 8.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_19 PF13245.1 EXF78362.1 - 0.043 13.5 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain AAA_18 PF13238.1 EXF78362.1 - 0.062 13.6 0.0 0.062 13.6 0.0 2.9 3 0 0 3 3 2 0 AAA domain SRPRB PF09439.5 EXF78362.1 - 0.066 12.4 0.1 6.3 5.9 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit T2SE PF00437.15 EXF78362.1 - 0.068 12.0 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein KAP_NTPase PF07693.9 EXF78362.1 - 0.075 12.0 0.0 0.094 11.6 0.0 1.6 1 1 0 1 1 1 0 KAP family P-loop domain Pox_A32 PF04665.7 EXF78362.1 - 0.095 11.9 0.4 0.49 9.6 0.0 2.2 3 0 0 3 3 2 0 Poxvirus A32 protein UPF0079 PF02367.12 EXF78362.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 EXF78362.1 - 0.12 11.8 0.5 0.66 9.4 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.1 EXF78362.1 - 0.13 12.5 0.0 1.4 9.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EXF78362.1 - 0.14 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DNA_RNApol_7kD PF03604.8 EXF78363.1 - 2.2e-15 55.8 7.8 2.7e-15 55.5 5.4 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit GFA PF04828.9 EXF78363.1 - 0.0025 17.7 1.1 1.2 9.1 0.0 2.1 1 1 1 2 2 2 2 Glutathione-dependent formaldehyde-activating enzyme GATA PF00320.22 EXF78363.1 - 0.004 16.4 0.1 0.004 16.4 0.0 2.2 2 1 0 2 2 2 1 GATA zinc finger HypA PF01155.14 EXF78363.1 - 0.0057 16.3 0.3 0.0057 16.3 0.2 1.1 1 0 0 1 1 1 1 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EXF78363.1 - 0.029 14.1 1.5 0.042 13.6 1.0 1.2 1 0 0 1 1 1 0 Double zinc ribbon FYDLN_acid PF09538.5 EXF78363.1 - 0.1 13.1 0.5 0.13 12.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Zn_Tnp_IS1595 PF12760.2 EXF78363.1 - 0.12 12.1 2.7 0.81 9.5 0.2 2.2 2 1 0 2 2 2 0 Transposase zinc-ribbon domain Prok-RING_1 PF14446.1 EXF78363.1 - 0.14 11.9 1.5 0.2 11.3 1.0 1.2 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-ISL3 PF14690.1 EXF78363.1 - 0.19 11.7 0.7 0.19 11.7 0.5 1.9 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Zn_ribbon_recom PF13408.1 EXF78363.1 - 0.2 11.9 2.9 4.9 7.4 0.5 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Zn-ribbon_8 PF09723.5 EXF78363.1 - 0.27 11.1 4.5 0.87 9.5 3.1 1.8 1 1 0 1 1 1 0 Zinc ribbon domain A2L_zn_ribbon PF08792.5 EXF78363.1 - 0.45 10.0 4.2 5 6.6 0.2 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain TF_Zn_Ribbon PF08271.7 EXF78363.1 - 2.4 7.5 7.2 1.8 7.9 0.1 2.2 1 1 1 2 2 2 0 TFIIB zinc-binding HIT PF01230.18 EXF78364.1 - 2.4e-18 66.4 0.0 3.8e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EXF78364.1 - 3.3e-07 30.5 0.0 7.6e-07 29.3 0.0 1.5 2 0 0 2 2 2 1 Scavenger mRNA decapping enzyme C-term binding CwfJ_C_1 PF04677.10 EXF78364.1 - 2.1e-05 24.1 0.0 6.1e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 Aldo_ket_red PF00248.16 EXF78365.1 - 1.1e-52 178.6 0.0 1.3e-52 178.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Iso_dh PF00180.15 EXF78367.1 - 9.6e-120 399.6 0.0 1.7e-119 398.8 0.0 1.4 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase ATP-synt_ab PF00006.20 EXF78367.1 - 2.8e-113 376.7 0.0 4.4e-113 376.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EXF78367.1 - 1.5e-18 67.3 1.3 3.1e-18 66.2 0.9 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EXF78367.1 - 7.8e-15 54.8 3.5 2.2e-14 53.3 1.9 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain DUF4048 PF13257.1 EXF78368.1 - 1.1e-14 54.7 1.7 1.1e-14 54.7 1.2 4.5 3 1 2 5 5 5 3 Domain of unknown function (DUF4048) DNA_ligase_A_M PF01068.16 EXF78369.1 - 3e-22 78.9 0.1 5.6e-22 78.1 0.1 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EXF78369.1 - 2e-16 60.3 0.0 6.8e-16 58.5 0.0 1.8 2 0 0 2 2 2 1 DNA ligase N terminus DIOX_N PF14226.1 EXF78370.1 - 1.8e-21 76.8 0.0 3e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EXF78370.1 - 3.9e-13 49.5 0.0 8.8e-13 48.3 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MKT1_C PF12246.3 EXF78371.1 - 5.2e-64 215.5 0.0 7.2e-64 215.0 0.0 1.2 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EXF78371.1 - 1.1e-26 92.9 0.1 2.3e-26 91.9 0.0 1.6 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication XPG_N PF00752.12 EXF78371.1 - 0.00038 20.6 0.0 0.0014 18.8 0.0 2.0 1 0 0 1 1 1 1 XPG N-terminal domain DNMT1-RFD PF12047.3 EXF78372.1 - 0.00094 18.8 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 Cytosine specific DNA methyltransferase replication foci domain TruB_N PF01509.13 EXF78373.1 - 1e-44 152.2 0.0 3.3e-44 150.6 0.0 1.8 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) Sec2p PF06428.6 EXF78374.1 - 9.3e-11 41.4 9.1 9.3e-11 41.4 6.3 2.0 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p SlyX PF04102.7 EXF78374.1 - 0.0046 17.2 8.5 0.68 10.3 1.7 3.1 2 1 1 3 3 3 2 SlyX MbeD_MobD PF04899.7 EXF78374.1 - 0.14 12.0 7.5 0.63 9.9 0.4 3.2 2 1 1 3 3 3 0 MbeD/MobD like IncA PF04156.9 EXF78374.1 - 0.26 10.8 11.0 7.1 6.1 6.0 2.3 2 0 0 2 2 2 0 IncA protein DUF2360 PF10152.4 EXF78374.1 - 0.62 10.3 6.7 2.6 8.3 4.6 2.1 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF3782 PF12644.2 EXF78374.1 - 0.82 9.5 3.8 2.7 7.8 2.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) Lzipper-MIP1 PF14389.1 EXF78374.1 - 0.93 9.6 8.9 4.4 7.4 3.3 3.0 2 1 1 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 HR1 PF02185.11 EXF78374.1 - 4 7.2 12.5 14 5.4 3.4 3.4 3 1 0 3 3 3 0 Hr1 repeat Jnk-SapK_ap_N PF09744.4 EXF78374.1 - 5.1 7.0 9.9 5.9 6.8 0.0 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 EXOSC1 PF10447.4 EXF78375.1 - 1.1e-26 92.5 0.8 1.8e-26 91.9 0.5 1.3 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EXF78375.1 - 7.9e-13 47.4 0.6 1.9e-12 46.2 0.3 1.7 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region ERG2_Sigma1R PF04622.7 EXF78376.1 - 6.3e-96 319.7 0.4 7e-96 319.6 0.3 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein PTR2 PF00854.16 EXF78377.1 - 1.3e-42 145.8 14.2 4.1e-28 98.2 1.2 2.6 3 0 0 3 3 3 2 POT family Zn_clus PF00172.13 EXF78379.1 - 8.8e-07 28.7 9.3 1.5e-06 28.0 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF78379.1 - 0.0014 17.3 0.5 0.0022 16.6 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ERbeta_N PF12497.3 EXF78379.1 - 0.039 13.8 0.0 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Estrogen receptor beta DUF2797 PF10977.3 EXF78379.1 - 0.055 13.0 2.4 0.098 12.2 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Glyco_hydro_3 PF00933.16 EXF78380.1 - 1.4e-84 283.5 0.0 2.1e-84 283.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF78380.1 - 6.8e-47 159.8 0.0 1.1e-46 159.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF78380.1 - 2.9e-22 78.3 0.0 5.3e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain FAD_binding_4 PF01565.18 EXF78381.1 - 7.7e-23 80.5 1.5 1.9e-22 79.2 1.0 1.7 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF78381.1 - 2.1e-08 33.9 2.2 2.6e-08 33.6 0.5 1.9 2 0 0 2 2 2 1 Berberine and berberine like DUF1772 PF08592.6 EXF78382.1 - 4.3e-23 81.5 0.1 6e-23 81.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) AA_permease PF00324.16 EXF78383.1 - 8.7e-129 429.9 52.4 1e-128 429.7 36.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF78383.1 - 1e-32 113.2 58.3 1.2e-32 113.0 40.4 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2665 PF11654.3 EXF78383.1 - 0.069 12.7 0.2 0.21 11.1 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2665) Amidohydro_2 PF04909.9 EXF78384.1 - 5.6e-46 157.3 0.4 7e-46 156.9 0.3 1.0 1 0 0 1 1 1 1 Amidohydrolase DUF1932 PF09130.6 EXF78385.1 - 7.2e-19 67.3 0.1 1.4e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) F420_oxidored PF03807.12 EXF78385.1 - 0.00012 22.3 0.2 0.00024 21.4 0.1 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EXF78385.1 - 0.00033 20.5 0.0 0.00054 19.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EXF78385.1 - 0.022 14.4 0.0 0.049 13.2 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HET PF06985.6 EXF78386.1 - 2.1e-24 86.2 0.0 3.6e-24 85.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Methyltransf_23 PF13489.1 EXF78389.1 - 5.2e-20 71.7 0.0 8.5e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF78389.1 - 5.1e-12 46.3 0.0 5.5e-11 43.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF78389.1 - 3.5e-10 39.6 0.0 7.1e-10 38.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF78389.1 - 3.4e-09 37.0 0.0 7.6e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF78389.1 - 4.6e-09 36.6 0.0 3.7e-08 33.7 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF78389.1 - 9.8e-06 25.8 0.0 2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF78389.1 - 0.00048 19.2 0.0 0.0011 18.0 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 EXF78389.1 - 0.0013 18.7 0.0 0.0099 15.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF78389.1 - 0.0024 17.2 0.0 0.02 14.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EXF78389.1 - 0.0095 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase CMAS PF02353.15 EXF78389.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 EXF78389.1 - 0.019 14.1 0.0 0.064 12.4 0.0 1.8 2 0 0 2 2 2 0 O-methyltransferase PrmA PF06325.8 EXF78389.1 - 0.041 13.0 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EXF78389.1 - 0.06 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.14 EXF78389.1 - 0.13 11.7 0.0 0.64 9.5 0.0 1.9 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GidB PF02527.10 EXF78389.1 - 0.13 11.4 0.0 0.71 8.9 0.0 2.2 2 1 0 2 2 2 0 rRNA small subunit methyltransferase G Glyco_hydro_75 PF07335.6 EXF78390.1 - 1.5e-46 158.0 0.2 1.9e-46 157.7 0.1 1.1 1 0 0 1 1 1 1 Fungal chitosanase of glycosyl hydrolase group 75 p450 PF00067.17 EXF78391.1 - 5.6e-64 216.3 0.0 8.9e-64 215.7 0.0 1.2 1 1 0 1 1 1 1 Cytochrome P450 Abhydrolase_6 PF12697.2 EXF78392.1 - 4.2e-31 108.5 0.1 5.5e-31 108.2 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF78392.1 - 9.9e-17 61.2 0.0 1.6e-11 44.2 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF78392.1 - 1.8e-13 50.4 0.0 4.6e-13 49.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EXF78392.1 - 1e-05 25.3 0.0 2.3e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.3 EXF78392.1 - 0.00014 21.6 0.0 0.00041 20.1 0.0 1.7 2 0 0 2 2 2 1 Putative lysophospholipase Ndr PF03096.9 EXF78392.1 - 0.02 13.3 0.0 0.045 12.2 0.0 1.5 1 0 0 1 1 1 0 Ndr family Esterase PF00756.15 EXF78392.1 - 0.031 13.7 0.1 0.043 13.2 0.0 1.4 1 1 0 1 1 1 0 Putative esterase Acyl_transf_2 PF02273.10 EXF78392.1 - 0.045 12.7 0.0 0.083 11.8 0.0 1.4 1 0 0 1 1 1 0 Acyl transferase PGAP1 PF07819.8 EXF78392.1 - 0.049 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S28 PF05577.7 EXF78392.1 - 0.07 11.6 0.0 0.095 11.2 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 NAD_binding_2 PF03446.10 EXF78393.1 - 2.8e-31 108.5 0.0 4.1e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EXF78393.1 - 2.7e-21 75.8 0.0 4.4e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase GFO_IDH_MocA PF01408.17 EXF78393.1 - 0.00027 21.4 0.2 0.0006 20.3 0.1 1.7 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.12 EXF78393.1 - 0.0011 19.3 0.1 0.004 17.5 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent CoA_binding PF02629.14 EXF78393.1 - 0.019 15.4 0.1 0.046 14.2 0.1 1.6 1 0 0 1 1 1 0 CoA binding domain Saccharop_dh PF03435.13 EXF78393.1 - 0.026 13.5 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_Gly3P_dh_N PF01210.18 EXF78393.1 - 0.034 13.8 0.0 0.15 11.7 0.0 2.0 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 EXF78393.1 - 0.069 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EXF78393.1 - 0.1 11.9 0.2 0.86 8.9 0.1 2.1 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_10 PF13460.1 EXF78394.1 - 3.1e-09 37.1 0.0 1.3e-06 28.5 0.0 2.2 1 1 1 2 2 2 2 NADH(P)-binding adh_short PF00106.20 EXF78395.1 - 9.8e-25 87.3 0.0 1.5e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF78395.1 - 1.3e-11 44.4 0.0 2.5e-11 43.5 0.0 1.4 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF78395.1 - 4.7e-10 39.6 0.0 6.7e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EXF78395.1 - 8.8e-08 31.8 0.1 7.2e-07 28.8 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EXF78395.1 - 0.004 15.8 0.0 0.0078 14.9 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF2493 PF10686.4 EXF78395.1 - 0.01 15.3 0.1 0.046 13.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2493) Polysacc_synt_2 PF02719.10 EXF78395.1 - 0.019 13.8 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EXF78395.1 - 0.049 13.6 0.0 0.085 12.8 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EXF78395.1 - 0.14 11.9 0.1 0.38 10.5 0.0 1.7 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 EXF78395.1 - 0.15 11.1 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain p450 PF00067.17 EXF78396.1 - 1.8e-66 224.5 0.0 2.1e-66 224.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 NAD_binding_2 PF03446.10 EXF78397.1 - 7.8e-38 129.8 0.0 1.7e-37 128.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EXF78397.1 - 3.4e-24 85.2 0.0 6.5e-24 84.3 0.0 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase CMD PF02627.15 EXF78397.1 - 3.6e-20 71.6 0.3 8.6e-20 70.3 0.2 1.7 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family OCD_Mu_crystall PF02423.10 EXF78397.1 - 1.3e-05 24.1 0.0 2.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family F420_oxidored PF03807.12 EXF78397.1 - 0.00011 22.5 0.0 0.00037 20.8 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Lactamase_B PF00753.22 EXF78397.1 - 0.0012 18.5 3.0 0.0088 15.7 2.1 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EXF78397.1 - 0.0014 18.2 0.0 0.0025 17.4 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain GFO_IDH_MocA PF01408.17 EXF78397.1 - 0.088 13.3 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Fungal_trans PF04082.13 EXF78398.1 - 1.5e-07 30.5 0.3 3e-07 29.6 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EXF78398.1 - 1.8e-05 24.8 20.6 0.00097 19.3 2.1 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Lactamase_B PF00753.22 EXF78398.1 - 6.8e-05 22.6 0.0 0.00013 21.6 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EXF78398.1 - 0.00011 21.8 0.1 0.00024 20.7 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EXF78398.1 - 0.0023 17.6 0.0 0.0056 16.4 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain zf-C2H2_4 PF13894.1 EXF78398.1 - 0.0034 17.6 19.5 0.1 12.9 2.0 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EXF78398.1 - 0.072 13.4 24.4 0.037 14.3 7.3 3.0 3 0 0 3 3 3 0 Zinc-finger double domain FAD_binding_4 PF01565.18 EXF78399.1 - 1.1e-19 70.2 0.1 1.7e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Lectin_leg-like PF03388.8 EXF78400.1 - 5.6e-25 87.8 0.0 9.8e-25 87.0 0.0 1.3 1 0 0 1 1 1 1 Legume-like lectin family DUF4592 PF15262.1 EXF78400.1 - 0.019 15.4 3.7 0.036 14.5 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4592) PDGLE PF13190.1 EXF78400.1 - 0.052 13.2 0.1 5.2 6.8 0.0 2.9 3 0 0 3 3 3 0 PDGLE domain Suf PF05843.9 EXF78400.1 - 0.095 12.4 3.3 0.13 11.9 2.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2360 PF10152.4 EXF78400.1 - 0.11 12.7 7.3 3.3 7.9 0.1 2.4 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) PAT1 PF09770.4 EXF78400.1 - 0.17 10.0 18.4 0.24 9.6 12.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BAF1_ABF1 PF04684.8 EXF78400.1 - 0.32 9.7 17.8 0.44 9.3 12.3 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Prog_receptor PF02161.10 EXF78400.1 - 0.4 9.4 5.0 0.63 8.8 3.4 1.2 1 0 0 1 1 1 0 Progesterone receptor Alg6_Alg8 PF03155.10 EXF78401.1 - 7.3e-143 476.7 27.2 9.2e-143 476.4 18.9 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WAC_Acf1_DNA_bd PF10537.4 EXF78403.1 - 3.4e-38 129.9 0.0 3.4e-38 129.9 0.0 2.9 4 0 0 4 4 4 1 ATP-utilising chromatin assembly and remodelling N-terminal DDT PF02791.12 EXF78403.1 - 1.4e-18 66.4 1.0 2.5e-18 65.5 0.7 1.5 1 0 0 1 1 1 1 DDT domain WHIM2 PF15613.1 EXF78403.1 - 1.3e-13 50.2 0.3 2.6e-13 49.3 0.2 1.5 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 2 WHIM3 PF15614.1 EXF78403.1 - 0.002 17.8 0.1 0.0051 16.5 0.1 1.7 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 3 WHIM1 PF15612.1 EXF78403.1 - 0.003 17.4 0.6 0.01 15.7 0.1 2.2 2 0 0 2 2 2 1 WSTF, HB1, Itc1p, MBD9 motif 1 RNase_H PF00075.19 EXF78404.1 - 7.7e-13 48.9 0.0 1.2e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 RNase H RVT_3 PF13456.1 EXF78404.1 - 0.032 13.9 0.0 0.078 12.7 0.0 1.7 1 0 0 1 1 1 0 Reverse transcriptase-like Zn_clus PF00172.13 EXF78405.1 - 5e-09 35.9 13.3 9.1e-09 35.0 9.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF78405.1 - 4.7e-05 22.1 0.0 7.1e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Metallophos PF00149.23 EXF78407.1 - 8.2e-11 41.6 2.2 1.6e-10 40.6 1.5 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EXF78407.1 - 1.2e-07 31.7 0.0 2.3e-07 30.7 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Amidohydro_4 PF13147.1 EXF78408.1 - 2.9e-20 73.4 0.7 3.6e-16 60.0 0.0 3.2 3 1 0 3 3 3 2 Amidohydrolase Amidohydro_5 PF13594.1 EXF78408.1 - 9.1e-10 38.2 0.2 2.2e-07 30.5 0.1 2.7 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EXF78408.1 - 6.1e-09 35.9 0.2 5.8e-06 26.1 0.0 3.1 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_3 PF07969.6 EXF78408.1 - 8.1e-06 25.3 0.3 0.025 13.7 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase family DUF3936 PF13072.1 EXF78408.1 - 0.17 11.3 0.1 7.8 6.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3936) DUF1996 PF09362.5 EXF78409.1 - 5.9e-60 202.8 0.6 8e-60 202.4 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Serglycin PF04360.7 EXF78409.1 - 0.081 12.6 4.4 0.17 11.5 3.0 1.5 1 0 0 1 1 1 0 Serglycin Nol1_Nop2_Fmu PF01189.12 EXF78410.1 - 6.4e-19 68.4 0.0 2.4e-13 50.1 0.0 2.4 2 1 0 2 2 2 2 NOL1/NOP2/sun family Thioredoxin_6 PF13848.1 EXF78412.1 - 7.4e-21 74.7 0.0 1.4e-09 38.0 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.15 EXF78412.1 - 0.0097 15.5 0.0 0.063 12.9 0.0 2.3 4 0 0 4 4 4 1 Thioredoxin MFS_1 PF07690.11 EXF78413.1 - 1.3e-37 129.3 46.5 1.3e-37 129.3 32.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF78413.1 - 0.015 13.8 36.6 0.0028 16.2 20.5 2.6 1 1 1 2 2 2 0 Sugar (and other) transporter VirionAssem_T7 PF11653.3 EXF78413.1 - 0.19 12.4 0.8 0.51 11.1 0.6 1.7 1 0 0 1 1 1 0 Bacteriophage T7 virion assembly protein BTB PF00651.26 EXF78414.1 - 1e-06 28.6 0.0 1.8e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DUF4140 PF13600.1 EXF78416.1 - 0.014 15.8 0.2 0.03 14.7 0.1 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) GrpB PF04229.9 EXF78416.1 - 0.073 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 GrpB protein TMF_DNA_bd PF12329.3 EXF78416.1 - 0.11 12.3 0.1 0.21 11.4 0.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SH3BGR PF04908.10 EXF78417.1 - 0.15 12.0 1.0 0.28 11.1 0.4 1.7 1 1 1 2 2 2 0 SH3-binding, glutamic acid-rich protein MFS_1 PF07690.11 EXF78419.1 - 7.9e-46 156.3 60.1 4.2e-40 137.5 23.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF78419.1 - 1.3e-14 53.6 34.8 2.1e-13 49.6 24.1 2.8 1 1 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EXF78419.1 - 3.3e-06 25.5 3.6 6.1e-06 24.7 2.5 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EXF78419.1 - 0.5 8.3 13.2 0.12 10.3 0.8 3.5 2 1 2 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family DUF3353 PF11833.3 EXF78419.1 - 0.69 9.3 7.3 10 5.4 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3353) DUF1434 PF07254.7 EXF78419.1 - 8.1 6.2 7.1 7.9 6.3 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1434) HTH_12 PF08461.5 EXF78420.1 - 0.12 12.0 1.5 0.38 10.5 1.1 1.8 1 1 0 1 1 1 0 Ribonuclease R winged-helix domain Herpes_IE1 PF07340.6 EXF78421.1 - 0.32 9.3 0.2 0.48 8.7 0.1 1.2 1 0 0 1 1 1 0 Cytomegalovirus IE1 protein Chitin_synth_2 PF03142.10 EXF78422.1 - 4.3e-25 88.0 1.7 4.3e-25 88.0 1.2 2.8 3 0 0 3 3 3 2 Chitin synthase Glyco_tranf_2_3 PF13641.1 EXF78422.1 - 1.8e-17 63.9 0.0 4e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EXF78422.1 - 5.3e-17 62.1 4.5 5.3e-17 62.1 3.1 2.5 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EXF78422.1 - 0.0053 16.4 0.1 0.49 10.0 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 2 HSP70 PF00012.15 EXF78423.1 - 2.4e-161 537.6 7.1 2.4e-161 537.6 4.9 2.5 1 1 1 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EXF78423.1 - 7.6e-14 51.0 0.2 7.1e-13 47.8 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.1 EXF78423.1 - 2.8e-06 27.1 1.5 0.015 15.1 0.2 3.3 2 1 0 2 2 2 2 Cell division protein FtsA GTP_EFTU PF00009.22 EXF78424.1 - 1.4e-32 112.7 0.0 8e-32 110.2 0.0 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EXF78424.1 - 1.1e-18 67.0 0.1 2.9e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EXF78424.1 - 2e-09 37.4 4.5 4.7e-07 29.8 0.1 3.1 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EXF78424.1 - 1.9e-06 27.7 0.1 1.3e-05 25.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EXF78424.1 - 0.0026 17.3 0.0 0.01 15.4 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.1 EXF78424.1 - 0.045 13.8 0.1 0.69 10.0 0.0 3.0 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EXF78424.1 - 0.097 12.6 0.0 0.097 12.6 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain MMS1_N PF10433.4 EXF78425.1 - 1e-85 287.8 0.0 1.6e-85 287.1 0.0 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term RabGAP-TBC PF00566.13 EXF78426.1 - 6.1e-21 74.8 0.1 1.2e-20 73.9 0.0 1.5 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Vps52 PF04129.7 EXF78427.1 - 1.5e-126 422.9 0.0 2e-126 422.5 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 EXF78427.1 - 4.7e-06 25.0 2.0 2.3e-05 22.7 1.4 1.8 1 1 0 1 1 1 1 Exocyst complex component Sec3 DUF869 PF05911.6 EXF78427.1 - 0.0023 16.2 0.6 0.0034 15.7 0.4 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) IncA PF04156.9 EXF78427.1 - 0.15 11.6 1.6 0.41 10.2 0.2 2.2 2 0 0 2 2 2 0 IncA protein Filament PF00038.16 EXF78427.1 - 0.21 11.0 3.4 0.36 10.2 0.0 2.4 3 0 0 3 3 3 0 Intermediate filament protein eIF-5a PF01287.15 EXF78428.1 - 1.3e-24 85.9 1.4 1.9e-24 85.3 0.9 1.3 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EXF78428.1 - 6e-05 22.5 0.8 6e-05 22.5 0.6 1.8 2 0 0 2 2 2 1 KOW motif EFP_N PF08207.7 EXF78428.1 - 0.008 16.0 0.2 0.03 14.1 0.0 2.0 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain RRN7 PF11781.3 EXF78429.1 - 5.6e-05 22.5 0.6 9.4e-05 21.8 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 Yip1 PF04893.12 EXF78430.1 - 1.6e-11 44.0 16.4 1.6e-11 44.0 11.4 1.4 1 1 0 1 1 1 1 Yip1 domain Rhodanese PF00581.15 EXF78431.1 - 1.1e-13 51.4 0.0 1.8e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain DUF1517 PF07466.6 EXF78433.1 - 0.02 13.8 0.7 4.3 6.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) stn_TNFRSF12A PF12191.3 EXF78433.1 - 0.025 14.5 1.5 1.6 8.8 0.0 3.1 3 0 0 3 3 3 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain HAD PF12710.2 EXF78434.1 - 2e-09 37.8 0.1 3e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.7 EXF78434.1 - 0.0016 17.6 0.0 0.0078 15.4 0.0 1.8 1 1 0 1 1 1 1 Putative Phosphatase Hydrolase PF00702.21 EXF78434.1 - 0.01 16.2 0.4 0.14 12.5 0.1 2.4 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EXF78434.1 - 0.072 12.3 0.0 0.23 10.7 0.0 1.9 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) Coatomer_E PF04733.9 EXF78435.1 - 2.9e-62 210.5 7.0 3.2e-62 210.3 4.8 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit Apc3 PF12895.2 EXF78435.1 - 1.1e-06 28.6 1.4 0.26 11.4 0.0 3.5 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EXF78435.1 - 1.4e-06 28.7 11.0 0.0036 17.9 0.5 4.9 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EXF78435.1 - 2.8e-06 27.4 17.0 0.014 15.9 2.0 5.7 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 EXF78435.1 - 2.2e-05 23.6 6.2 0.015 14.3 2.3 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EXF78435.1 - 2.3e-05 24.6 22.9 0.032 14.5 2.3 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EXF78435.1 - 0.00014 21.4 4.4 0.13 11.9 0.0 4.3 3 1 2 5 5 5 1 TPR repeat TPR_12 PF13424.1 EXF78435.1 - 0.0019 18.0 13.9 1.4 8.9 0.6 5.1 2 2 4 6 6 6 2 Tetratricopeptide repeat Type_III_YscG PF09477.5 EXF78435.1 - 0.0021 18.1 6.7 0.031 14.3 0.1 3.7 1 1 3 4 4 4 1 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_8 PF13181.1 EXF78435.1 - 0.0039 16.8 0.3 2.1 8.3 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EXF78435.1 - 0.0056 16.2 5.4 1.9 8.2 0.1 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_4 PF07721.9 EXF78435.1 - 0.02 15.2 2.9 0.095 13.1 0.9 5.6 8 0 0 8 8 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EXF78435.1 - 0.085 13.3 5.2 12 6.6 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 EXF78435.1 - 0.1 12.7 5.0 4 7.6 0.1 3.0 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EXF78435.1 - 0.11 12.2 11.2 15 5.7 0.3 5.4 6 1 1 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 EXF78435.1 - 0.21 11.5 11.2 5.3 7.1 0.4 4.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 EXF78435.1 - 0.39 10.5 5.2 9.3 6.1 0.4 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EXF78435.1 - 0.6 10.1 17.3 0.15 12.0 0.6 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat SAM_2 PF07647.12 EXF78437.1 - 3.7e-14 52.3 0.0 7.5e-14 51.3 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SH3_9 PF14604.1 EXF78437.1 - 3.7e-12 45.6 0.0 9.4e-12 44.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EXF78437.1 - 2.1e-10 39.8 0.0 4.2e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 EXF78437.1 - 5.3e-09 36.2 0.0 1.4e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EXF78437.1 - 3.8e-06 27.1 0.1 1.1e-05 25.6 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain SH3_2 PF07653.12 EXF78437.1 - 4.9e-05 22.7 0.0 0.00011 21.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.1 EXF78437.1 - 0.028 14.4 0.0 0.18 11.9 0.0 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain SAM_1 PF00536.25 EXF78437.1 - 0.084 13.0 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) zf-MIZ PF02891.15 EXF78438.1 - 7e-08 31.8 4.1 4.4e-06 26.1 0.3 2.5 2 0 0 2 2 2 2 MIZ/SP-RING zinc finger DUF4611 PF15387.1 EXF78438.1 - 0.044 13.9 0.9 0.11 12.7 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Arrestin_N PF00339.24 EXF78439.1 - 2.7e-14 53.2 0.0 3.7e-09 36.5 0.0 2.7 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain PGAP1 PF07819.8 EXF78440.1 - 1.6e-07 31.1 0.0 3.1e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EXF78440.1 - 5.9e-06 25.7 0.0 1.2e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EXF78440.1 - 2.5e-05 24.2 0.5 4.1e-05 23.5 0.3 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 EXF78440.1 - 0.00093 18.2 0.0 0.0013 17.7 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.15 EXF78440.1 - 0.0014 18.2 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EXF78440.1 - 0.016 14.8 0.0 0.036 13.6 0.0 1.6 1 0 0 1 1 1 0 Serine hydrolase Lipase_2 PF01674.13 EXF78440.1 - 0.023 14.0 0.0 0.08 12.2 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 2) DUF915 PF06028.6 EXF78440.1 - 0.032 13.2 0.1 0.12 11.4 0.0 1.9 3 0 0 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydro_lipase PF04083.11 EXF78440.1 - 0.051 12.9 0.0 0.091 12.1 0.0 1.3 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DUF900 PF05990.7 EXF78440.1 - 0.12 11.7 0.0 0.2 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) RTA1 PF04479.8 EXF78442.1 - 9.5e-14 51.4 3.9 1.5e-13 50.8 2.7 1.2 1 0 0 1 1 1 1 RTA1 like protein Rhomboid PF01694.17 EXF78443.1 - 1.3e-14 54.4 4.8 2.3e-14 53.6 3.3 1.4 1 0 0 1 1 1 1 Rhomboid family DNA_pol3_tau_4 PF12168.3 EXF78444.1 - 0.43 11.0 3.2 0.96 9.8 0.5 2.0 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding DUF4337 PF14235.1 EXF78445.1 - 0.13 12.1 0.1 0.18 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) TPR_12 PF13424.1 EXF78446.1 - 0.0014 18.5 3.0 0.0024 17.7 2.1 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EXF78446.1 - 0.0017 17.9 2.1 0.0026 17.3 1.4 1.2 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 EXF78446.1 - 0.0057 16.2 1.4 0.032 13.8 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.4 EXF78446.1 - 0.019 14.9 0.8 0.023 14.6 0.5 1.3 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_2 PF07719.12 EXF78446.1 - 0.38 10.7 5.0 0.47 10.5 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M15_2 PF05951.8 EXF78447.1 - 0.016 14.6 0.1 0.051 13.0 0.1 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) NAD_binding_6 PF08030.7 EXF78449.1 - 2.2e-22 79.6 0.0 3.1e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.14 EXF78449.1 - 2.6e-10 40.4 12.3 2.6e-10 40.4 8.6 1.9 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EXF78449.1 - 2.3e-09 37.0 0.0 5e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Methyltransf_18 PF12847.2 EXF78450.1 - 1.1e-08 35.6 0.0 1.6e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF78450.1 - 8.4e-05 22.3 0.0 9.4e-05 22.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EXF78450.1 - 9.5e-05 21.3 0.0 0.00021 20.2 0.0 1.5 1 1 1 2 2 2 1 DREV methyltransferase Methyltransf_11 PF08241.7 EXF78450.1 - 0.00025 21.4 0.0 0.00036 20.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EXF78450.1 - 0.00037 19.5 0.0 0.00044 19.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 EXF78450.1 - 0.0011 18.3 0.0 0.0014 18.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EXF78450.1 - 0.0062 16.9 0.0 0.0093 16.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EXF78450.1 - 0.013 15.0 0.1 0.029 13.9 0.0 1.5 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EXF78450.1 - 0.023 14.3 0.0 0.03 13.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EXF78450.1 - 0.079 12.0 0.0 0.093 11.8 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EXF78450.1 - 0.082 12.8 0.0 0.098 12.6 0.0 1.1 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EXF78450.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF3197 PF11432.3 EXF78450.1 - 0.11 12.5 0.1 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3197) Cys_Met_Meta_PP PF01053.15 EXF78453.1 - 3.9e-57 193.2 0.0 8.6e-57 192.1 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EXF78453.1 - 0.11 11.4 0.0 0.22 10.4 0.0 1.4 1 1 0 1 1 1 0 Aminotransferase class I and II Terpene_synth_C PF03936.11 EXF78454.1 - 1.6e-11 43.9 0.8 2.2e-11 43.4 0.6 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Polysacc_deac_1 PF01522.16 EXF78455.1 - 5e-21 74.5 0.0 1e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Polysacc_deac_2 PF04748.8 EXF78455.1 - 0.053 12.5 0.0 0.085 11.8 0.0 1.3 1 0 0 1 1 1 0 Divergent polysaccharide deacetylase Hamartin PF04388.7 EXF78457.1 - 1.2 7.7 15.3 1.4 7.4 10.6 1.1 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.8 EXF78457.1 - 8.1 6.2 9.1 11 5.7 6.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.27 EXF78458.1 - 2.9e-25 87.1 7.8 2.1e-07 30.5 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 EXF78458.1 - 0.00027 19.2 3.8 0.00089 17.5 0.5 2.3 1 1 1 2 2 2 2 Nucleoporin Nup120/160 Cyclin_N PF00134.18 EXF78458.1 - 0.13 11.8 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Cyclin, N-terminal domain HA2 PF04408.18 EXF78459.1 - 1.4e-26 92.4 0.1 2.1e-25 88.6 0.0 2.7 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EXF78459.1 - 1.2e-24 86.2 0.0 4.4e-24 84.5 0.0 2.0 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EXF78459.1 - 2.9e-08 33.4 0.0 8.3e-08 31.9 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EXF78459.1 - 4.3e-07 29.5 0.0 1e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EXF78459.1 - 0.00042 20.2 0.0 0.44 10.3 0.0 2.7 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit T2SE PF00437.15 EXF78459.1 - 0.00049 19.0 0.0 0.00098 18.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EXF78459.1 - 0.00056 20.0 0.0 0.0013 18.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.4 EXF78459.1 - 0.0017 17.4 0.0 0.0029 16.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.17 EXF78459.1 - 0.004 16.6 0.0 0.0079 15.6 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain KaiC PF06745.8 EXF78459.1 - 0.0051 15.9 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 KaiC Flavi_DEAD PF07652.9 EXF78459.1 - 0.024 14.3 0.0 0.045 13.4 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain GAD PF02938.9 EXF78459.1 - 0.026 14.6 0.0 0.063 13.4 0.0 1.6 1 0 0 1 1 1 0 GAD domain AAA_10 PF12846.2 EXF78459.1 - 0.027 13.9 0.4 7.1 5.9 0.1 2.3 2 0 0 2 2 2 0 AAA-like domain Myosin_head PF00063.16 EXF78459.1 - 0.056 11.4 0.0 0.094 10.7 0.0 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) AAA_25 PF13481.1 EXF78459.1 - 0.061 12.7 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.15 EXF78459.1 - 0.065 11.9 0.4 0.12 10.9 0.3 1.4 1 0 0 1 1 1 0 G-protein alpha subunit AAA_14 PF13173.1 EXF78459.1 - 0.07 13.0 0.1 0.42 10.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EXF78459.1 - 0.079 13.2 0.3 0.23 11.7 0.0 2.0 2 0 0 2 2 1 0 ABC transporter NACHT PF05729.7 EXF78459.1 - 0.12 12.0 0.3 0.57 9.8 0.1 2.1 2 0 0 2 2 2 0 NACHT domain Acylphosphatase PF00708.13 EXF78460.1 - 5.5e-25 87.2 0.1 6e-25 87.1 0.1 1.0 1 0 0 1 1 1 1 Acylphosphatase Hep_59 PF07052.6 EXF78461.1 - 6.2e-16 58.6 0.0 6.2e-16 58.6 0.0 2.7 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 IncA PF04156.9 EXF78463.1 - 0.66 9.5 6.0 0.92 9.0 4.1 1.2 1 0 0 1 1 1 0 IncA protein BTK PF00779.14 EXF78464.1 - 0.0058 16.2 0.8 0.01 15.4 0.5 1.4 1 0 0 1 1 1 1 BTK motif AAA_29 PF13555.1 EXF78464.1 - 0.055 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Lactamase_B_3 PF13483.1 EXF78465.1 - 4.2e-07 29.8 0.0 2.4e-06 27.3 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain BPL_LplA_LipB PF03099.14 EXF78468.1 - 2.9e-14 53.1 0.0 9.4e-14 51.4 0.0 1.9 2 1 0 2 2 2 1 Biotin/lipoate A/B protein ligase family Chorismate_synt PF01264.16 EXF78469.1 - 2.6e-124 414.1 0.0 3.4e-124 413.8 0.0 1.1 1 0 0 1 1 1 1 Chorismate synthase Peptidase_M24 PF00557.19 EXF78470.1 - 7.6e-07 28.9 0.0 1.2e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Glyco_hydro_71 PF03659.9 EXF78471.1 - 1e-145 485.0 5.4 1e-145 485.0 3.7 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 Tyrosinase PF00264.15 EXF78473.1 - 2.5e-51 174.9 4.4 5.5e-51 173.8 3.0 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase Fungal_trans_2 PF11951.3 EXF78478.1 - 1.7e-61 207.9 0.0 2.1e-61 207.6 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF78478.1 - 1.2e-07 31.5 14.5 2.1e-07 30.7 10.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EXF78479.1 - 3.1e-15 55.7 42.8 2.6e-14 52.7 25.7 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF78479.1 - 1.4e-06 27.1 9.4 1.4e-06 27.1 6.5 2.5 3 0 0 3 3 3 1 Sugar (and other) transporter UNC-93 PF05978.11 EXF78479.1 - 0.00027 20.4 7.4 0.00027 20.4 5.2 2.0 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 VIT1 PF01988.14 EXF78479.1 - 9.1 5.6 15.0 2.6 7.4 4.9 2.5 2 0 0 2 2 2 0 VIT family DAO PF01266.19 EXF78480.1 - 1.2e-52 179.0 0.3 1.4e-52 178.8 0.2 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EXF78480.1 - 8.7e-05 22.3 1.3 0.082 12.6 0.1 2.9 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EXF78480.1 - 0.00018 21.6 0.0 0.014 15.4 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF78480.1 - 0.0023 17.0 0.2 0.036 13.1 0.0 2.5 2 1 1 3 3 3 1 Thi4 family NAD_binding_8 PF13450.1 EXF78480.1 - 0.022 14.7 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EXF78480.1 - 0.052 12.0 0.1 0.54 8.6 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Galanin PF01296.13 EXF78480.1 - 0.095 12.5 0.2 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 Galanin Pyr_redox PF00070.22 EXF78480.1 - 0.3 11.5 2.1 1.4e+02 2.9 0.0 3.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HAD_2 PF13419.1 EXF78481.1 - 1.4e-24 87.3 0.0 1.7e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EXF78481.1 - 0.00014 22.3 0.0 0.009 16.4 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.1 EXF78481.1 - 0.052 13.4 0.0 14 5.6 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 EXF78482.1 - 2e-44 151.7 54.2 9.6e-42 142.9 20.9 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF78482.1 - 3.2e-13 49.0 9.2 3.2e-13 49.0 6.4 2.6 3 0 0 3 3 3 1 Sugar (and other) transporter SPC25 PF06703.6 EXF78482.1 - 0.26 10.8 0.8 0.6 9.6 0.5 1.5 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) p450 PF00067.17 EXF78483.1 - 4.7e-50 170.4 0.0 7e-50 169.8 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 DIT1_PvcA PF05141.7 EXF78484.1 - 1.9e-99 332.4 0.0 2.5e-99 332.1 0.0 1.1 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein DUF4066 PF13278.1 EXF78485.1 - 2.3e-22 79.0 0.0 3e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EXF78485.1 - 4.3e-10 39.2 0.0 6.1e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family Urm1 PF09138.6 EXF78486.1 - 1.3e-32 111.8 0.0 1.5e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EXF78486.1 - 0.00058 20.2 0.1 0.0015 18.9 0.0 1.7 2 0 0 2 2 2 1 ThiS family WD40 PF00400.27 EXF78487.1 - 3.4e-56 185.2 14.4 8.8e-08 31.7 0.1 11.5 12 0 0 12 12 12 9 WD domain, G-beta repeat DUF3317 PF11779.3 EXF78488.1 - 4.2e-17 61.3 5.8 5.6e-17 60.9 4.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3317) Ion_trans_N PF08412.5 EXF78488.1 - 0.057 12.7 1.3 0.082 12.2 0.9 1.2 1 0 0 1 1 1 0 Ion transport protein N-terminal Pex24p PF06398.6 EXF78488.1 - 0.11 11.2 1.3 0.11 11.2 0.9 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Cytochrome-c551 PF10643.4 EXF78488.1 - 0.58 9.4 2.8 0.75 9.0 1.9 1.4 1 1 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 RF-1 PF00472.15 EXF78489.1 - 1.8e-25 88.9 5.2 2.1e-25 88.7 3.1 1.4 1 1 0 1 1 1 1 RF-1 domain S-antigen PF05756.6 EXF78489.1 - 0.026 14.5 2.4 0.04 13.9 1.6 1.2 1 0 0 1 1 1 0 S-antigen protein Rhabdo_ncap PF00945.13 EXF78489.1 - 0.2 10.1 2.5 0.26 9.8 1.7 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Herpes_UL25 PF01499.11 EXF78489.1 - 0.6 8.3 4.3 0.76 8.0 3.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family CAML PF14963.1 EXF78489.1 - 0.98 8.7 6.8 1.3 8.3 4.7 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Actin PF00022.14 EXF78490.1 - 2.4e-158 526.6 0.0 2.7e-158 526.5 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EXF78490.1 - 0.036 14.4 0.0 0.12 12.8 0.0 1.8 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Fes1 PF08609.5 EXF78492.1 - 4.5e-31 107.1 2.1 4.6e-31 107.1 0.7 1.6 2 0 0 2 2 2 1 Nucleotide exchange factor Fes1 Arm PF00514.18 EXF78492.1 - 2e-06 27.3 0.3 0.03 14.1 0.0 2.7 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EXF78492.1 - 4.2e-06 27.0 1.5 2.6e-05 24.5 0.4 2.6 2 0 0 2 2 2 1 HEAT-like repeat HEAT_2 PF13646.1 EXF78492.1 - 1.2e-05 25.5 1.7 2.5e-05 24.4 0.1 2.3 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.17 EXF78492.1 - 4.4e-05 23.2 0.3 0.045 13.8 0.0 2.9 3 0 0 3 3 3 2 HEAT repeat Osmo_CC PF08946.5 EXF78492.1 - 1.1 9.2 4.3 2.4 8.2 0.1 2.7 3 0 0 3 3 3 0 Osmosensory transporter coiled coil Ribosomal_L5_C PF00673.16 EXF78493.1 - 1.6e-20 72.6 0.0 2.3e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EXF78493.1 - 0.00027 20.6 0.1 0.00046 19.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L5 UCH_1 PF13423.1 EXF78494.1 - 2.4e-80 270.1 1.0 5.2e-80 269.0 0.7 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase 6PF2K PF01591.13 EXF78495.1 - 6.8e-61 205.1 0.0 1e-60 204.5 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EXF78495.1 - 4.8e-22 78.7 0.3 7.6e-22 78.0 0.2 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_17 PF13207.1 EXF78495.1 - 8.7e-05 23.3 1.1 0.0077 17.0 0.0 2.7 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.1 EXF78495.1 - 0.00018 21.3 0.0 0.00093 19.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain Porin_3 PF01459.17 EXF78496.1 - 1.1e-87 293.8 0.7 1.3e-87 293.6 0.5 1.0 1 0 0 1 1 1 1 Eukaryotic porin NmrA PF05368.8 EXF78497.1 - 3.2e-20 72.4 0.0 4.1e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF78497.1 - 1.8e-09 37.8 0.0 3.4e-09 36.9 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 EXF78497.1 - 8.9e-05 22.4 0.3 0.00027 20.8 0.0 1.9 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 EXF78497.1 - 0.00024 20.2 0.0 0.00047 19.2 0.0 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EXF78497.1 - 0.0015 18.6 0.0 0.0027 17.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Epimerase PF01370.16 EXF78497.1 - 0.011 15.2 0.0 0.62 9.4 0.0 2.4 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EXF78497.1 - 0.019 15.2 0.0 0.035 14.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain HET PF06985.6 EXF78498.1 - 2.5e-19 69.8 7.1 2.4e-16 60.1 0.7 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) DUF3684 PF12449.3 EXF78499.1 - 0 1437.3 0.1 0 1436.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3684) HATPase_c_3 PF13589.1 EXF78499.1 - 1.4e-05 24.7 0.0 3.9e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sec16_C PF12931.2 EXF78500.1 - 9.4e-98 327.4 0.1 1.3e-97 327.0 0.0 1.2 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 EXF78500.1 - 2.5e-29 101.6 0.0 5.2e-29 100.6 0.0 1.6 1 0 0 1 1 1 1 Vesicle coat trafficking protein Sec16 mid-region E1-E2_ATPase PF00122.15 EXF78501.1 - 1.3e-16 60.3 0.0 3e-16 59.1 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EXF78501.1 - 2.5e-15 57.4 0.0 7.9e-15 55.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EXF78501.1 - 6.7e-10 39.4 0.0 1.7e-09 38.1 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EXF78501.1 - 9e-05 22.3 0.0 0.00035 20.4 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EXF78501.1 - 0.0012 18.4 0.0 0.0027 17.3 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FAD_binding_6 PF00970.19 EXF78502.1 - 9.9e-06 25.6 0.0 0.0014 18.7 0.0 2.8 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EXF78502.1 - 0.001 19.6 0.0 0.002 18.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Suc_Fer-like PF06999.7 EXF78504.1 - 1.5e-49 169.1 0.0 3.8e-49 167.7 0.0 1.6 2 0 0 2 2 2 1 Sucrase/ferredoxin-like HsbA PF12296.3 EXF78507.1 - 1.6e-16 60.2 1.8 1.6e-16 60.2 1.3 1.7 1 1 1 2 2 2 1 Hydrophobic surface binding protein A HWE_HK PF07536.9 EXF78507.1 - 0.012 16.0 0.7 0.026 14.9 0.0 2.0 2 0 0 2 2 2 0 HWE histidine kinase DUF4244 PF14029.1 EXF78507.1 - 0.034 13.2 1.2 0.079 12.0 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4244) DUF948 PF06103.6 EXF78507.1 - 2.5 7.9 6.1 4.6 7.1 0.0 3.5 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Glyco_hydro_3 PF00933.16 EXF78508.1 - 5.7e-82 275.0 0.0 9.1e-82 274.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF78508.1 - 1.2e-44 152.5 0.0 2.6e-44 151.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF78508.1 - 3e-17 62.2 0.2 7.8e-17 60.9 0.1 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EXF78508.1 - 3.6e-08 33.1 0.1 7.6e-08 32.1 0.1 1.5 1 0 0 1 1 1 1 PA14 domain DUF840 PF05801.6 EXF78508.1 - 0.026 14.6 0.0 0.15 12.1 0.0 2.2 2 0 0 2 2 2 0 Lagovirus protein of unknown function (DUF840) Aldo_ket_red PF00248.16 EXF78509.1 - 5.5e-42 143.5 0.0 7e-42 143.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Fungal_trans PF04082.13 EXF78510.1 - 2.3e-08 33.2 0.7 5.2e-08 32.0 0.5 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain AA_permease PF00324.16 EXF78512.1 - 6.7e-116 387.4 48.5 8e-116 387.1 33.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF78512.1 - 4.4e-33 114.4 51.4 6.2e-33 113.9 35.6 1.1 1 0 0 1 1 1 1 Amino acid permease PQ-loop PF04193.9 EXF78513.1 - 9.8e-25 85.8 2.4 3.3e-17 61.7 0.1 3.0 2 1 0 2 2 2 2 PQ loop repeat An_peroxidase PF03098.10 EXF78514.1 - 9.8e-97 324.5 0.0 5.8e-94 315.3 0.0 2.1 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EXF78514.1 - 2.5e-08 32.8 0.0 2.2e-06 26.4 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 Acyl_transf_3 PF01757.17 EXF78515.1 - 5.8e-30 104.2 38.1 1.7e-29 102.7 24.8 2.3 2 1 0 2 2 2 1 Acyltransferase family DUF1600 PF07667.6 EXF78515.1 - 2.8 8.0 6.5 1.7 8.7 0.3 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1600) adh_short PF00106.20 EXF78516.1 - 9e-15 54.9 1.1 1.2e-14 54.5 0.3 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF78516.1 - 0.00017 21.2 0.1 0.00026 20.7 0.1 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EXF78516.1 - 0.049 13.7 0.1 0.08 13.0 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3328 PF11807.3 EXF78517.1 - 4.2e-50 170.4 0.5 5e-50 170.2 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF1180 PF06679.7 EXF78518.1 - 5.4 6.8 6.8 8.4 6.2 4.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) Thymidylate_kin PF02223.12 EXF78520.1 - 3.6e-45 153.6 0.0 2.3e-44 150.9 0.0 1.8 2 0 0 2 2 2 1 Thymidylate kinase AAA_28 PF13521.1 EXF78520.1 - 1.7e-05 24.8 0.0 3.3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EXF78520.1 - 0.04 13.1 0.0 0.075 12.2 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 APS_kinase PF01583.15 EXF78520.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase COesterase PF00135.23 EXF78521.1 - 5.8e-76 256.3 0.0 7.6e-76 255.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF78521.1 - 6.5e-09 35.6 0.1 1e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold TYA PF01021.14 EXF78522.1 - 0.014 15.6 0.2 0.028 14.5 0.1 1.4 1 0 0 1 1 1 0 TYA transposon protein DUF4190 PF13828.1 EXF78522.1 - 3 7.4 7.2 16 5.0 5.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4190) SAM_decarbox PF01536.11 EXF78523.1 - 8.5e-85 284.3 0.0 1.5e-81 273.6 0.0 3.7 1 1 0 1 1 1 1 Adenosylmethionine decarboxylase ParA PF10609.4 EXF78524.1 - 8.3e-37 124.9 0.1 1.7e-36 123.9 0.1 1.5 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EXF78524.1 - 6.8e-16 58.2 0.0 1.2e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MipZ PF09140.6 EXF78524.1 - 7.8e-08 31.7 0.0 3.1e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 ATPase MipZ AAA_31 PF13614.1 EXF78524.1 - 2.5e-05 24.2 0.1 8.9e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 EXF78524.1 - 3.2e-05 23.1 0.3 7.4e-05 21.9 0.2 1.6 1 0 0 1 1 1 1 Anion-transporting ATPase ArgK PF03308.11 EXF78524.1 - 0.00087 18.1 0.4 0.0014 17.4 0.3 1.3 1 0 0 1 1 1 1 ArgK protein AAA_25 PF13481.1 EXF78524.1 - 0.001 18.5 0.1 0.0017 17.7 0.1 1.3 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.1 EXF78524.1 - 0.003 17.2 0.2 0.33 10.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain YhjQ PF06564.7 EXF78524.1 - 0.018 14.4 0.2 0.031 13.6 0.1 1.5 2 0 0 2 2 2 0 YhjQ protein APS_kinase PF01583.15 EXF78524.1 - 0.054 13.1 0.1 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF258 PF03193.11 EXF78524.1 - 0.084 12.0 1.8 0.084 12.0 0.2 1.8 3 0 0 3 3 3 0 Protein of unknown function, DUF258 Fer4_NifH PF00142.13 EXF78524.1 - 0.1 11.7 0.1 0.33 10.1 0.0 1.8 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_16 PF13191.1 EXF78524.1 - 0.21 11.5 0.9 0.61 10.0 0.5 1.8 2 0 0 2 2 2 0 AAA ATPase domain p450 PF00067.17 EXF78526.1 - 1.1e-94 317.5 0.0 1.4e-94 317.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PhoQ_Sensor PF08918.5 EXF78526.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.2 1 0 0 1 1 1 0 PhoQ Sensor Zn_clus PF00172.13 EXF78527.1 - 5.9e-19 67.7 27.7 2.4e-10 40.1 4.9 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF78527.1 - 9.2e-13 47.6 0.1 1.4e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain NOB1_Zn_bind PF08772.6 EXF78528.1 - 3.9e-32 109.8 3.4 6.7e-32 109.1 2.4 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like UPF0278 PF08745.6 EXF78528.1 - 0.027 13.7 0.2 13 4.9 0.0 3.1 2 1 1 3 3 3 0 UPF0278 family zf-NADH-PPase PF09297.6 EXF78528.1 - 0.12 11.9 3.0 0.15 11.5 0.2 2.3 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain AF1Q PF15017.1 EXF78528.1 - 0.19 11.6 10.8 1.1 9.2 7.5 2.3 1 1 0 1 1 1 0 Drug resistance and apoptosis regulator Nop10p PF04135.7 EXF78529.1 - 5.5e-21 74.0 0.0 6.5e-21 73.8 0.0 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family DUF3328 PF11807.3 EXF78530.1 - 3.4e-19 69.3 0.9 1.4e-16 60.8 0.3 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF3328) Bac_rhamnosid PF05592.6 EXF78532.1 - 2.1e-177 590.4 0.9 2.6e-177 590.1 0.6 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 EXF78532.1 - 5.2e-57 192.1 0.0 1.1e-56 191.0 0.0 1.6 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain DUF3344 PF11824.3 EXF78532.1 - 0.00053 19.4 0.2 0.00099 18.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3344) MBD PF01429.14 EXF78532.1 - 0.14 11.7 0.0 3 7.4 0.0 2.8 3 0 0 3 3 3 0 Methyl-CpG binding domain SFTA2 PF15210.1 EXF78532.1 - 0.14 11.7 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 Surfactant-associated protein 2 adh_short PF00106.20 EXF78533.1 - 5.6e-26 91.4 0.1 1e-25 90.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF78533.1 - 1.4e-18 67.6 0.0 1.6e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF78533.1 - 8.7e-09 35.2 0.0 1.4e-08 34.5 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EXF78533.1 - 1.7e-05 24.9 0.1 5.5e-05 23.2 0.0 1.9 3 0 0 3 3 3 1 NADH(P)-binding DUF1776 PF08643.5 EXF78533.1 - 2.7e-05 23.4 0.1 3.9e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EXF78533.1 - 0.0077 15.6 0.0 0.015 14.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 EXF78533.1 - 0.018 14.5 0.0 0.051 13.1 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EXF78533.1 - 0.023 13.8 0.0 0.049 12.7 0.0 1.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MFS_1 PF07690.11 EXF78534.1 - 2.8e-32 111.8 20.2 2.3e-20 72.6 3.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EXF78534.1 - 1.7e-12 46.5 10.4 7e-08 31.2 0.3 2.8 2 1 0 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 EXF78534.1 - 5.2e-07 28.6 8.9 8.2e-07 27.9 6.1 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.2 EXF78534.1 - 0.00037 20.2 4.9 0.0012 18.5 0.1 3.4 4 0 0 4 4 4 1 MFS_1 like family PTR2 PF00854.16 EXF78534.1 - 0.00056 18.8 0.6 0.0015 17.4 0.0 2.0 2 0 0 2 2 2 1 POT family OATP PF03137.15 EXF78534.1 - 0.047 11.7 0.9 4.6 5.1 0.4 2.2 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family FA_hydroxylase PF04116.8 EXF78536.1 - 1e-13 51.6 9.5 1e-13 51.6 6.6 2.3 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily GFO_IDH_MocA PF01408.17 EXF78537.1 - 1.5e-17 64.2 0.2 2.4e-17 63.5 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold OpuAC PF04069.7 EXF78537.1 - 0.0063 15.8 0.1 3.3 7.0 0.0 2.3 2 0 0 2 2 2 2 Substrate binding domain of ABC-type glycine betaine transport system Semialdhyde_dh PF01118.19 EXF78537.1 - 0.079 13.2 0.1 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Aldo_ket_red PF00248.16 EXF78538.1 - 5.9e-20 71.2 0.0 1.1e-09 37.5 0.0 2.1 2 0 0 2 2 2 2 Aldo/keto reductase family NUT_C PF12882.2 EXF78538.1 - 0.0048 16.5 0.0 0.0081 15.7 0.0 1.4 1 0 0 1 1 1 1 NUT protein C terminal HTH_5 PF01022.15 EXF78540.1 - 0.021 14.4 0.0 0.034 13.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial regulatory protein, arsR family SNF2_N PF00176.18 EXF78541.1 - 2.1e-18 66.1 0.1 3.6e-18 65.4 0.0 1.4 2 0 0 2 2 2 1 SNF2 family N-terminal domain NACHT PF05729.7 EXF78542.1 - 3.6e-08 33.2 0.1 1.6e-07 31.1 0.0 2.1 2 0 0 2 2 2 1 NACHT domain AAA_16 PF13191.1 EXF78542.1 - 9.7e-06 25.6 0.5 8.3e-05 22.6 0.0 2.7 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EXF78542.1 - 5.3e-05 23.3 0.1 0.00083 19.4 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA PF00004.24 EXF78542.1 - 0.003 17.7 0.7 0.044 13.9 0.0 2.8 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EXF78542.1 - 0.0039 16.0 0.0 0.01 14.7 0.0 1.8 1 0 0 1 1 1 1 NB-ARC domain AAA_25 PF13481.1 EXF78542.1 - 0.0056 16.0 0.2 0.027 13.8 0.0 2.2 3 0 0 3 3 3 1 AAA domain KAP_NTPase PF07693.9 EXF78542.1 - 0.011 14.7 0.1 1.4 7.7 0.0 3.2 2 1 2 4 4 4 0 KAP family P-loop domain KaiC PF06745.8 EXF78542.1 - 0.012 14.7 0.0 0.038 13.0 0.0 1.8 1 1 0 1 1 1 0 KaiC PPV_E1_C PF00519.12 EXF78542.1 - 0.019 13.6 0.0 0.041 12.4 0.0 1.5 1 0 0 1 1 1 0 Papillomavirus helicase AAA_33 PF13671.1 EXF78542.1 - 0.046 13.6 0.8 0.36 10.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EXF78542.1 - 0.047 13.8 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.1 EXF78542.1 - 0.084 13.7 0.0 1.9 9.3 0.0 2.8 3 0 0 3 3 3 0 AAA domain ResIII PF04851.10 EXF78542.1 - 0.12 12.2 0.0 0.32 10.8 0.0 1.7 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DAP3 PF10236.4 EXF78542.1 - 0.13 11.2 1.0 1.4 7.8 0.0 2.2 1 1 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 VTC PF09359.5 EXF78544.1 - 6.6e-93 310.7 0.3 1.4e-92 309.7 0.2 1.5 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EXF78544.1 - 3.3e-16 59.9 29.0 3.9e-15 56.3 12.0 4.1 2 1 0 2 2 2 1 SPX domain DUF202 PF02656.10 EXF78544.1 - 4.2e-10 39.7 1.7 4.2e-10 39.7 1.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Lbh PF15317.1 EXF78544.1 - 0.026 14.7 0.0 0.15 12.3 0.0 2.3 2 0 0 2 2 2 0 Cardiac transcription factor regulator, Developmental protein FGGY_C PF02782.11 EXF78545.1 - 6.8e-47 159.6 0.4 1.1e-46 158.9 0.3 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EXF78545.1 - 3.9e-17 62.3 1.4 3.2e-15 56.1 1.0 3.2 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain Myb_DNA-binding PF00249.26 EXF78546.1 - 4.8e-13 48.9 2.0 1.6e-06 28.0 0.4 2.6 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EXF78546.1 - 1.1e-11 44.6 0.9 4.3e-05 23.5 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Glyco_hydro_16 PF00722.16 EXF78547.1 - 6e-43 146.2 4.2 6e-43 146.2 2.9 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 DNA_pol_viral_N PF00242.12 EXF78547.1 - 0.012 14.6 1.6 0.018 14.1 1.1 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain PET PF06297.9 EXF78547.1 - 0.11 12.1 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 PET Domain NAD_binding_10 PF13460.1 EXF78548.1 - 2.5e-13 50.4 0.0 3.7e-13 49.8 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EXF78548.1 - 0.0081 15.4 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Lactonase PF10282.4 EXF78549.1 - 4.5e-54 183.8 0.2 1.3e-53 182.2 0.2 1.7 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller SBP56 PF05694.6 EXF78549.1 - 0.0018 16.8 0.0 0.64 8.4 0.0 2.2 2 0 0 2 2 2 2 56kDa selenium binding protein (SBP56) Cytochrom_D1 PF02239.11 EXF78549.1 - 0.02 13.1 0.1 0.72 8.0 0.0 2.4 2 1 1 3 3 3 0 Cytochrome D1 heme domain DUF4604 PF15377.1 EXF78550.1 - 4.5e-23 82.1 11.8 5.6e-23 81.9 8.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) COX5B PF01215.14 EXF78551.1 - 9.8e-36 122.4 0.0 1.3e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Zn-ribbon_8 PF09723.5 EXF78551.1 - 0.097 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Zinc ribbon domain IncA PF04156.9 EXF78552.1 - 0.0058 16.2 6.2 0.0058 16.2 4.3 2.2 2 0 0 2 2 2 1 IncA protein LRS4 PF10422.4 EXF78552.1 - 0.028 13.8 11.2 0.019 14.3 2.1 2.4 2 0 0 2 2 2 0 Monopolin complex subunit LRS4 Med9 PF07544.8 EXF78552.1 - 0.042 13.5 4.6 0.098 12.4 0.3 3.0 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF641 PF04859.7 EXF78552.1 - 0.059 13.1 7.5 1.9 8.2 2.0 2.7 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) AAA_13 PF13166.1 EXF78552.1 - 0.11 10.9 5.0 0.22 9.9 3.4 1.4 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.4 EXF78552.1 - 4.5 6.1 13.9 0.14 11.0 5.1 1.7 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 4HBT_3 PF13622.1 EXF78553.1 - 1.2e-40 139.9 0.0 1.3e-40 139.7 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Amino_oxidase PF01593.19 EXF78555.1 - 6.6e-57 193.5 0.1 8.6e-57 193.1 0.1 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EXF78555.1 - 2.5e-16 59.4 0.3 5.9e-16 58.2 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF78555.1 - 8.1e-11 41.4 3.9 1.7e-09 37.0 2.7 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EXF78555.1 - 6.7e-08 32.8 1.7 0.00027 21.3 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF78555.1 - 1.6e-07 30.1 0.1 0.00013 20.6 0.1 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 EXF78555.1 - 9.5e-07 27.9 0.5 4.7e-06 25.7 0.5 1.9 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EXF78555.1 - 1.1e-05 24.6 0.3 1.9e-05 23.9 0.2 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EXF78555.1 - 4.1e-05 22.8 1.6 4.1e-05 22.8 0.4 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF78555.1 - 6.5e-05 22.8 0.4 0.00043 20.2 0.2 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EXF78555.1 - 0.0003 19.9 0.2 0.0036 16.4 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EXF78555.1 - 0.00056 18.8 0.3 0.00097 18.1 0.2 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EXF78555.1 - 0.0011 19.0 0.4 0.0091 16.0 0.4 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF78555.1 - 0.0066 15.4 1.2 0.011 14.7 0.4 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EXF78555.1 - 0.014 15.2 0.1 7.8 6.2 0.1 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding OHCU_decarbox PF09349.5 EXF78556.1 - 3.9e-39 134.5 0.5 4.7e-39 134.2 0.3 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Dor1 PF04124.7 EXF78556.1 - 0.006 15.0 0.3 0.0068 14.9 0.2 1.1 1 0 0 1 1 1 1 Dor1-like family Prp19 PF08606.6 EXF78557.1 - 8.4e-33 111.9 2.0 1.8e-32 110.8 1.4 1.6 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 EXF78557.1 - 7.6e-14 50.9 0.1 0.00011 21.9 0.0 5.0 6 0 0 6 6 6 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EXF78557.1 - 5.4e-06 25.4 0.0 0.033 13.0 0.0 2.1 1 1 1 2 2 2 2 Coatomer WD associated region eIF2A PF08662.6 EXF78557.1 - 0.00014 21.6 0.0 0.38 10.4 0.0 2.3 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A zf-Nse PF11789.3 EXF78557.1 - 0.0015 17.9 0.0 0.0036 16.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 EXF78557.1 - 0.0035 17.2 0.0 0.0071 16.2 0.0 1.5 1 0 0 1 1 1 1 U-box domain Lactonase PF10282.4 EXF78557.1 - 0.008 15.3 0.0 0.028 13.4 0.0 1.9 1 1 1 2 2 2 1 Lactonase, 7-bladed beta-propeller zf-RING_5 PF14634.1 EXF78558.1 - 9e-05 22.1 1.4 0.00023 20.7 1.0 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EXF78558.1 - 0.016 15.2 0.4 0.016 15.2 0.3 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EXF78558.1 - 0.019 14.5 0.5 0.045 13.4 0.3 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EXF78558.1 - 0.037 13.7 0.5 0.07 12.8 0.1 1.7 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.1 EXF78558.1 - 0.11 12.3 1.8 0.18 11.6 0.2 1.9 2 0 0 2 2 2 0 Ring finger domain Borrelia_P83 PF05262.6 EXF78559.1 - 2.1 6.5 15.2 0.96 7.6 8.3 1.8 2 0 0 2 2 2 0 Borrelia P83/100 protein WD40 PF00400.27 EXF78560.1 - 1.1e-28 98.0 4.3 1.1e-09 37.8 0.2 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EXF78560.1 - 1.6e-17 63.1 0.1 4.8e-17 61.6 0.0 1.9 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex CBM_1 PF00734.13 EXF78562.1 - 9.1e-09 34.8 9.2 9.1e-09 34.8 6.4 2.2 2 0 0 2 2 2 1 Fungal cellulose binding domain Toxin_7 PF05980.7 EXF78562.1 - 0.14 12.2 0.9 0.25 11.4 0.7 1.4 1 0 0 1 1 1 0 Toxin 7 Amidoligase_2 PF12224.3 EXF78563.1 - 2.4e-22 79.7 0.0 3.6e-22 79.2 0.0 1.3 1 1 0 1 1 1 1 Putative amidoligase enzyme Thioredoxin PF00085.15 EXF78564.1 - 4e-24 84.2 0.0 6.4e-24 83.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EXF78564.1 - 7.6e-07 29.1 0.0 7.7e-06 25.9 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EXF78564.1 - 2.1e-05 24.6 2.8 7.8e-05 22.8 0.1 2.6 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EXF78564.1 - 0.001 19.0 0.0 0.001 19.0 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like HyaE PF07449.6 EXF78564.1 - 0.047 13.5 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE TrbC_Ftype PF09673.5 EXF78564.1 - 0.1 12.2 0.1 11 5.6 0.0 2.3 1 1 1 2 2 2 0 Type-F conjugative transfer system pilin assembly protein Thioredoxin_9 PF14595.1 EXF78564.1 - 0.1 12.1 0.0 0.38 10.3 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin WD40 PF00400.27 EXF78565.1 - 8e-33 111.1 14.6 1.4e-10 40.5 0.1 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat IKI3 PF04762.7 EXF78565.1 - 0.043 11.6 0.1 4.1 5.0 0.0 2.1 1 1 1 2 2 2 0 IKI3 family PhnA_Zn_Ribbon PF08274.7 EXF78565.1 - 1.1 9.1 3.0 0.42 10.4 0.2 1.7 2 0 0 2 2 2 0 PhnA Zinc-Ribbon eRF1_1 PF03463.10 EXF78566.1 - 4.6e-39 133.0 0.0 8e-39 132.2 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 EXF78566.1 - 6.8e-22 78.2 0.0 1e-21 77.6 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EXF78566.1 - 1.1e-15 57.8 0.0 2e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 3 Aldo_ket_red PF00248.16 EXF78567.1 - 4.5e-45 153.6 0.0 6e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NmrA PF05368.8 EXF78569.1 - 5.1e-14 52.0 0.1 7.5e-14 51.5 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF78569.1 - 5e-12 46.1 0.0 7.8e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding ApbA PF02558.11 EXF78569.1 - 0.0026 17.2 0.1 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DapB_N PF01113.15 EXF78569.1 - 0.0029 17.5 0.6 0.006 16.4 0.4 1.6 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.16 EXF78569.1 - 0.0029 17.0 0.1 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EXF78569.1 - 0.0082 16.5 0.4 0.017 15.5 0.3 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Sigma54_activ_2 PF14532.1 EXF78569.1 - 0.02 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain KR PF08659.5 EXF78569.1 - 0.024 14.2 0.3 0.076 12.6 0.2 1.8 1 1 0 1 1 1 0 KR domain adh_short PF00106.20 EXF78569.1 - 0.026 14.4 0.8 0.034 14.0 0.1 1.6 2 1 0 2 2 2 0 short chain dehydrogenase Semialdhyde_dh PF01118.19 EXF78569.1 - 0.029 14.6 0.2 0.13 12.5 0.1 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 EXF78569.1 - 0.066 13.2 0.2 0.16 12.0 0.2 1.6 1 1 0 1 1 1 0 TrkA-N domain p450 PF00067.17 EXF78570.1 - 1.3e-46 159.1 0.0 1.8e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 zf-C2H2_4 PF13894.1 EXF78571.1 - 1.3e-08 34.5 43.6 0.00054 20.1 1.3 7.3 7 0 0 7 7 7 6 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF78571.1 - 5.7e-07 29.5 46.4 0.0004 20.5 3.4 6.8 6 0 0 6 6 6 5 Zinc finger, C2H2 type Cyt-b5 PF00173.23 EXF78573.1 - 7.8e-13 48.0 0.0 9.6e-13 47.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain TPR_12 PF13424.1 EXF78574.1 - 4.8e-12 45.6 4.6 2.4e-06 27.4 0.2 3.7 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EXF78574.1 - 7.8e-06 25.4 0.8 0.014 15.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EXF78574.1 - 9.6e-06 25.1 2.9 0.08 12.5 0.0 3.7 3 1 0 3 3 3 1 TPR repeat TPR_1 PF00515.23 EXF78574.1 - 0.00012 21.5 1.1 0.26 10.9 0.0 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EXF78574.1 - 0.0019 17.8 0.3 0.19 11.5 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EXF78574.1 - 0.0027 17.3 0.4 0.84 9.5 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Mito_fiss_reg PF05308.6 EXF78574.1 - 0.0032 16.8 2.4 0.0061 15.9 1.6 1.4 1 0 0 1 1 1 1 Mitochondrial fission regulator TPR_10 PF13374.1 EXF78574.1 - 0.0087 15.9 0.2 0.77 9.7 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EXF78574.1 - 0.075 13.1 0.0 0.28 11.3 0.0 2.0 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.4 EXF78574.1 - 0.089 12.1 0.9 2 7.7 0.0 2.6 3 0 0 3 3 3 0 26S proteasome subunit RPN7 Gloverin PF10793.4 EXF78574.1 - 0.1 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Gloverin-like protein TPR_21 PF09976.4 EXF78574.1 - 0.16 11.8 0.8 0.36 10.7 0.2 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EXF78574.1 - 0.2 12.1 2.2 6 7.5 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat CAP_N PF01213.14 EXF78574.1 - 0.63 9.2 5.2 1.2 8.3 3.6 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal bZIP_1 PF00170.16 EXF78576.1 - 2.2e-08 33.9 1.8 4.3e-08 33.0 1.3 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EXF78576.1 - 3.8e-05 23.4 2.3 3.8e-05 23.4 1.6 1.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.12 EXF78576.1 - 0.08 13.2 7.6 0.15 12.4 5.3 1.4 1 0 0 1 1 1 0 bZIP Maf transcription factor HABP4_PAI-RBP1 PF04774.10 EXF78577.1 - 0.0094 16.4 3.4 0.014 15.8 2.4 1.5 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family Fis1_TPR_C PF14853.1 EXF78578.1 - 0.031 14.1 0.0 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 Fis1 C-terminal tetratricopeptide repeat CFEM PF05730.6 EXF78579.1 - 3e-08 33.3 5.5 5.9e-08 32.4 3.8 1.5 1 0 0 1 1 1 1 CFEM domain Antimicrobial_4 PF08024.6 EXF78579.1 - 7 6.6 6.0 0.63 9.9 0.2 2.1 2 0 0 2 2 2 0 Ant antimicrobial peptide BCAS2 PF05700.6 EXF78580.1 - 5.1e-43 147.0 0.2 6.2e-43 146.8 0.2 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) TMF_TATA_bd PF12325.3 EXF78580.1 - 0.11 12.2 3.1 0.43 10.3 1.3 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding cNMP_binding PF00027.24 EXF78581.1 - 1.9e-42 142.9 0.0 6.6e-22 77.1 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain CDC50 PF03381.10 EXF78582.1 - 5.6e-104 347.2 0.2 7e-104 346.8 0.1 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family SPT16 PF08644.6 EXF78583.1 - 5.8e-57 191.8 0.4 2.9e-56 189.5 0.0 2.5 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EXF78583.1 - 3.4e-52 176.2 1.0 3.4e-52 176.2 0.7 2.1 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.7 EXF78583.1 - 2.5e-22 78.6 0.8 7.2e-22 77.1 0.1 2.2 2 0 0 2 2 2 1 Histone chaperone Rttp106-like Peptidase_M24 PF00557.19 EXF78583.1 - 8.8e-22 77.6 0.0 1.4e-21 76.9 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 CMD PF02627.15 EXF78584.1 - 9.1e-10 38.2 0.0 7.5e-09 35.3 0.0 2.1 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family CsbD PF05532.7 EXF78586.1 - 2.3e-16 59.1 20.5 9.2e-11 41.2 3.1 3.6 2 1 1 3 3 3 2 CsbD-like Aminotran_5 PF00266.14 EXF78587.1 - 1.4e-92 310.3 0.0 1.8e-92 309.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EXF78587.1 - 2.2e-06 27.0 0.0 3.2e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EXF78587.1 - 3.4e-05 23.0 0.0 9.6e-05 21.5 0.0 1.7 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.14 EXF78587.1 - 0.0043 15.5 0.0 0.0066 14.9 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 EXF78587.1 - 0.055 11.7 0.0 0.08 11.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.14 EXF78587.1 - 0.1 12.4 0.0 0.6 9.9 0.0 2.2 2 0 0 2 2 2 0 B12 binding domain BAR PF03114.13 EXF78588.1 - 1.1e-66 224.6 8.2 1.6e-66 224.1 5.7 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EXF78588.1 - 8.1e-16 57.1 0.1 1.8e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EXF78588.1 - 6e-15 54.5 0.0 1e-14 53.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EXF78588.1 - 5.1e-12 45.0 0.7 1.5e-11 43.6 0.0 2.1 3 0 0 3 3 3 1 Variant SH3 domain GldM_N PF12081.3 EXF78588.1 - 0.012 15.1 2.8 0.13 11.7 0.8 2.3 2 0 0 2 2 2 0 GldM N-terminal domain Vps5 PF09325.5 EXF78588.1 - 0.14 11.3 7.4 1.2 8.3 2.4 2.2 2 0 0 2 2 2 0 Vps5 C terminal like APG6 PF04111.7 EXF78588.1 - 2.4 7.1 9.5 6.5 5.7 4.4 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 F-box PF00646.28 EXF78589.1 - 1.2e-06 28.0 0.1 3e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EXF78589.1 - 8.7e-05 22.1 0.2 0.00028 20.5 0.0 2.0 2 0 0 2 2 2 1 F-box-like MOSC PF03473.12 EXF78590.1 - 8.4e-22 77.0 0.0 2.1e-21 75.7 0.0 1.7 1 0 0 1 1 1 1 MOSC domain Fer2 PF00111.22 EXF78590.1 - 8.7e-11 41.4 1.0 1.9e-10 40.3 0.7 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NAD_binding_1 PF00175.16 EXF78590.1 - 1.1e-07 32.3 0.1 4.8e-07 30.3 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain RRP7 PF12923.2 EXF78591.1 - 9.4e-34 116.2 12.8 9.4e-34 116.2 8.8 1.9 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) Usp PF00582.21 EXF78591.1 - 0.44 10.7 5.7 1.5 8.9 0.1 2.7 2 1 0 2 2 2 0 Universal stress protein family Acetyltransf_6 PF13480.1 EXF78591.1 - 7 6.6 9.5 4.4 7.2 0.0 3.1 3 1 0 3 3 3 0 Acetyltransferase (GNAT) domain SH2_2 PF14633.1 EXF78593.1 - 3.1e-77 258.5 0.0 1e-76 256.8 0.0 1.9 1 0 0 1 1 1 1 SH2 domain DLD PF14878.1 EXF78593.1 - 5.9e-38 129.5 3.7 5.9e-38 129.5 2.6 4.4 3 0 0 3 3 3 1 Death-like domain of SPT6 HHH_7 PF14635.1 EXF78593.1 - 6.4e-30 103.3 0.0 1.3e-29 102.3 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 EXF78593.1 - 2.5e-29 101.7 0.0 1.4e-28 99.3 0.0 2.4 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 SPT6_acidic PF14632.1 EXF78593.1 - 2.9e-23 81.8 34.0 2.9e-23 81.8 23.6 7.0 5 1 1 7 7 7 1 Acidic N-terminal SPT6 HTH_44 PF14641.1 EXF78593.1 - 7.8e-17 61.3 1.6 7.8e-17 61.3 1.1 2.7 2 1 0 2 2 2 1 Helix-turn-helix DNA-binding domain of SPT6 SH2 PF00017.19 EXF78593.1 - 0.00019 21.1 0.0 0.0005 19.8 0.0 1.8 1 0 0 1 1 1 1 SH2 domain HHH_3 PF12836.2 EXF78593.1 - 0.0055 16.6 0.0 0.018 14.9 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif Pkinase PF00069.20 EXF78594.1 - 7.1e-60 202.3 0.0 9.3e-60 201.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF78594.1 - 3.9e-40 137.5 0.0 5e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF78594.1 - 5e-06 25.6 0.0 1.1e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EXF78594.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 HAD_2 PF13419.1 EXF78595.1 - 1.3e-09 38.5 0.0 4.3e-09 36.8 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EXF78595.1 - 1.3e-07 31.1 0.2 2.1e-07 30.5 0.1 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EXF78595.1 - 6.4e-07 29.9 0.0 8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EXF78595.1 - 0.045 13.9 0.0 0.071 13.2 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase FUSC_2 PF13515.1 EXF78596.1 - 7.6e-23 80.8 8.9 7.6e-23 80.8 6.2 2.6 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 EXF78596.1 - 5.2e-08 31.8 1.5 5.2e-08 31.8 1.1 2.4 2 0 0 2 2 2 1 Fusaric acid resistance protein family DUF2421 PF10334.4 EXF78596.1 - 0.012 15.2 0.0 0.039 13.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2421) ALMT PF11744.3 EXF78596.1 - 0.03 12.9 21.3 5.2 5.6 9.6 4.4 3 2 0 3 3 3 0 Aluminium activated malate transporter FlxA PF14282.1 EXF78597.1 - 0.00097 19.0 0.3 0.0026 17.6 0.2 1.6 1 0 0 1 1 1 1 FlxA-like protein Ribosomal_L16 PF00252.13 EXF78599.1 - 1.9e-31 108.5 0.1 2.5e-31 108.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Ribosomal_L7Ae PF01248.21 EXF78600.1 - 2e-24 84.8 0.0 2.4e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Z1 PF10593.4 EXF78601.1 - 0.038 13.1 3.8 0.088 12.0 2.6 1.6 1 0 0 1 1 1 0 Z1 domain Herpes_UL6 PF01763.11 EXF78601.1 - 0.14 10.2 7.0 0.28 9.3 4.8 1.4 1 0 0 1 1 1 0 Herpesvirus UL6 like Transposase_22 PF02994.9 EXF78601.1 - 0.17 10.3 17.9 0.82 8.0 0.0 2.5 1 1 1 2 2 2 0 L1 transposable element TipAS PF07739.8 EXF78601.1 - 0.71 10.1 12.2 0.51 10.6 3.7 2.8 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain DUF4615 PF15393.1 EXF78601.1 - 1.9 8.7 11.6 0.42 10.8 5.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4615) Laminin_II PF06009.7 EXF78601.1 - 2 8.1 16.7 2.6 7.7 8.0 2.9 2 1 0 2 2 2 0 Laminin Domain II ERM PF00769.14 EXF78601.1 - 2.2 7.7 37.6 4.1 6.8 2.5 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family LMBR1 PF04791.11 EXF78601.1 - 3.7 6.0 7.3 6.3 5.2 5.1 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein IncA PF04156.9 EXF78601.1 - 6.2 6.3 37.3 0.038 13.5 13.5 3.1 3 0 0 3 3 3 0 IncA protein Hormone_1 PF00103.15 EXF78601.1 - 8.5 5.6 10.2 26 4.0 3.7 2.5 2 0 0 2 2 2 0 Somatotropin hormone family V_ATPase_I PF01496.14 EXF78601.1 - 9 4.0 15.2 4.2 5.1 7.9 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF953 PF06110.6 EXF78602.1 - 1.5e-18 66.3 0.1 1.8e-18 66.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.15 EXF78602.1 - 0.00055 19.5 0.1 0.0009 18.8 0.1 1.4 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EXF78602.1 - 0.075 13.1 0.0 10 6.2 0.0 2.2 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_9 PF14595.1 EXF78602.1 - 0.11 12.0 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Vac7 PF12751.2 EXF78603.1 - 1.2e-122 409.5 5.1 1.2e-122 409.5 3.6 2.1 3 0 0 3 3 3 1 Vacuolar segregation subunit 7 RrnaAD PF00398.15 EXF78604.1 - 1.5e-21 76.6 0.0 1.6e-21 76.4 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase RrnaAD PF00398.15 EXF78605.1 - 6.8e-23 81.0 0.0 8.2e-23 80.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EXF78605.1 - 5e-10 39.4 0.0 7.5e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF78605.1 - 1.7e-07 31.8 0.0 2.4e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EXF78605.1 - 2.9e-05 23.6 0.0 3.4e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EXF78605.1 - 4.5e-05 23.2 0.0 5.1e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EXF78605.1 - 0.00013 21.1 0.0 0.00017 20.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.1 EXF78605.1 - 0.00039 20.0 0.0 0.0005 19.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF78605.1 - 0.00059 19.2 0.0 0.00076 18.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_12 PF08242.7 EXF78605.1 - 0.0011 19.3 0.0 0.0032 17.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF78605.1 - 0.0038 16.2 0.0 0.0046 16.0 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_11 PF08241.7 EXF78605.1 - 0.0074 16.7 0.0 0.011 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EXF78605.1 - 0.0093 15.5 0.0 0.022 14.3 0.0 1.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Ubie_methyltran PF01209.13 EXF78605.1 - 0.018 14.1 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.12 EXF78605.1 - 0.028 13.8 0.0 0.046 13.1 0.0 1.4 1 1 1 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_25 PF13649.1 EXF78605.1 - 0.033 14.5 0.0 0.046 14.0 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 EXF78605.1 - 0.066 12.4 0.0 0.071 12.2 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase NodS PF05401.6 EXF78605.1 - 0.11 11.9 0.0 0.13 11.6 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) PRP1_N PF06424.7 EXF78606.1 - 1.8e-52 177.1 8.1 5e-52 175.7 5.6 1.8 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EXF78606.1 - 7.4e-34 113.1 31.4 0.00095 19.5 0.2 14.3 4 3 10 14 14 14 11 Tetratricopeptide repeat TPR_16 PF13432.1 EXF78606.1 - 9.4e-26 89.8 16.4 1.1e-07 32.2 1.2 9.5 7 1 3 10 10 10 7 Tetratricopeptide repeat TPR_19 PF14559.1 EXF78606.1 - 1.5e-24 86.1 19.2 7.7e-07 29.3 0.3 9.0 5 3 3 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.1 EXF78606.1 - 3.4e-17 61.8 10.0 0.00053 19.5 0.0 8.3 6 2 1 8 8 8 4 TPR repeat TPR_2 PF07719.12 EXF78606.1 - 1e-14 53.1 10.8 0.092 12.7 0.0 10.6 11 1 1 12 12 10 2 Tetratricopeptide repeat TPR_17 PF13431.1 EXF78606.1 - 5.3e-11 41.8 3.6 3.2 8.2 0.0 8.6 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_15 PF13429.1 EXF78606.1 - 3.3e-10 39.4 17.9 6.3e-05 22.1 3.2 6.5 2 2 3 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EXF78606.1 - 9.7e-10 37.5 1.3 0.058 13.2 0.0 7.9 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_1 PF00515.23 EXF78606.1 - 1.7e-07 30.5 0.3 0.089 12.4 0.0 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat NARP1 PF12569.3 EXF78606.1 - 4e-07 29.1 11.8 0.5 9.0 0.0 6.1 4 1 2 6 6 6 3 NMDA receptor-regulated protein 1 Suf PF05843.9 EXF78606.1 - 1.6e-06 28.1 0.4 0.9 9.2 0.0 5.4 5 2 0 5 5 5 1 Suppressor of forked protein (Suf) TPR_6 PF13174.1 EXF78606.1 - 3.9e-06 26.9 4.4 9.3 6.9 0.0 8.7 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_12 PF13424.1 EXF78606.1 - 4e-06 26.6 8.4 0.063 13.2 0.0 6.1 7 1 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EXF78606.1 - 1.9e-05 24.4 6.8 0.0046 16.7 0.0 5.7 5 1 1 6 6 6 1 Tetratricopeptide repeat Apc3 PF12895.2 EXF78606.1 - 0.00016 21.7 0.1 6.3 7.0 0.0 4.7 3 1 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 FAT PF02259.18 EXF78606.1 - 0.00031 19.8 8.5 1.6 7.6 0.1 4.6 4 1 1 5 5 5 3 FAT domain TPR_7 PF13176.1 EXF78606.1 - 0.0041 16.8 6.2 6.5 6.8 0.0 6.4 8 0 0 8 8 4 0 Tetratricopeptide repeat NRDE-2 PF08424.5 EXF78606.1 - 0.016 14.0 0.1 0.016 14.0 0.1 5.7 4 2 2 6 6 6 0 NRDE-2, necessary for RNA interference Cutinase PF01083.17 EXF78606.1 - 0.026 14.2 0.1 15 5.2 0.0 3.4 2 1 1 3 3 3 0 Cutinase DUF3808 PF10300.4 EXF78606.1 - 0.052 12.1 2.9 7.1 5.0 0.0 4.0 3 1 2 5 5 5 0 Protein of unknown function (DUF3808) TPR_21 PF09976.4 EXF78606.1 - 0.17 11.8 24.6 0.056 13.3 0.8 5.5 4 1 1 5 5 5 0 Tetratricopeptide repeat ChAPs PF09295.5 EXF78606.1 - 0.9 8.2 5.3 4.8 5.8 0.2 3.2 2 1 0 3 3 3 0 ChAPs (Chs5p-Arf1p-binding proteins) Apolipoprotein PF01442.13 EXF78607.1 - 0.0014 18.1 0.1 0.0019 17.7 0.1 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.6 EXF78607.1 - 0.012 15.6 2.4 0.015 15.3 1.7 1.0 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) HrpB2 PF09487.5 EXF78607.1 - 0.04 14.0 0.2 0.049 13.8 0.2 1.2 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) MRFAP1 PF15155.1 EXF78607.1 - 1 9.6 6.0 14 6.0 0.2 2.0 1 1 1 2 2 2 0 MORF4 family-associated protein1 Peroxin-13_N PF04088.8 EXF78608.1 - 0.087 12.7 0.1 0.24 11.3 0.1 1.7 1 0 0 1 1 1 0 Peroxin 13, N-terminal region PPR_2 PF13041.1 EXF78609.1 - 0.00011 22.1 2.4 0.11 12.5 0.2 2.8 2 0 0 2 2 2 2 PPR repeat family PPR_3 PF13812.1 EXF78609.1 - 0.00034 20.6 0.0 0.32 11.3 0.0 3.2 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.15 EXF78609.1 - 5.3 7.2 5.0 17 5.6 0.4 2.7 2 0 0 2 2 2 0 PPR repeat PP2C PF00481.16 EXF78610.1 - 6.3e-85 284.6 0.0 6.3e-85 284.6 0.0 1.4 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.1 EXF78610.1 - 0.00011 21.6 0.0 0.00027 20.4 0.0 1.7 1 0 0 1 1 1 1 Protein phosphatase 2C He_PIG PF05345.7 EXF78611.1 - 4.4e-11 42.6 18.2 0.00029 20.8 0.5 5.8 5 1 1 6 6 6 3 Putative Ig domain DUF4448 PF14610.1 EXF78611.1 - 4.8e-05 22.9 0.0 0.00012 21.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 EXF78611.1 - 5.6e-05 22.8 0.4 0.00019 21.1 0.3 1.9 1 0 0 1 1 1 1 TMEM154 protein family Herpes_gE PF02480.11 EXF78611.1 - 0.0023 16.2 0.0 0.0036 15.6 0.0 1.3 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E BatD PF13584.1 EXF78611.1 - 0.022 13.3 0.0 0.038 12.5 0.0 1.3 1 0 0 1 1 1 0 Oxygen tolerance SKG6 PF08693.5 EXF78611.1 - 0.12 11.6 4.1 0.42 9.9 2.9 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 EXF78611.1 - 0.16 11.5 1.0 0.34 10.5 0.7 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Hum_adeno_E3A PF05393.6 EXF78611.1 - 0.19 11.3 0.2 0.43 10.2 0.1 1.5 1 0 0 1 1 1 0 Human adenovirus early E3A glycoprotein Tweety PF04906.8 EXF78611.1 - 0.35 9.2 0.0 0.53 8.6 0.0 1.1 1 0 0 1 1 1 0 Tweety Methyltransf_16 PF10294.4 EXF78612.1 - 1.1e-44 151.9 0.0 1.3e-44 151.6 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EXF78612.1 - 0.00081 19.9 0.0 0.0012 19.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF78612.1 - 0.0053 16.1 0.0 0.0083 15.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EXF78612.1 - 0.036 13.7 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DPBB_1 PF03330.13 EXF78613.1 - 0.00053 19.9 0.4 0.0013 18.6 0.2 1.8 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel DUF605 PF04652.11 EXF78613.1 - 0.054 12.8 18.6 0.062 12.7 12.9 1.1 1 0 0 1 1 1 0 Vta1 like Totivirus_coat PF05518.6 EXF78613.1 - 9 3.9 15.9 12 3.5 11.0 1.1 1 0 0 1 1 1 0 Totivirus coat protein DAO PF01266.19 EXF78614.1 - 3.9e-47 160.9 4.4 4.8e-47 160.5 3.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF78614.1 - 0.0035 17.3 0.1 0.009 16.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EXF78614.1 - 0.032 14.3 0.0 5.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase eIF-5_eIF-2B PF01873.12 EXF78615.1 - 1.6e-44 150.5 0.9 2.5e-44 149.9 0.6 1.3 1 0 0 1 1 1 1 Domain found in IF2B/IF5 MYT1 PF08474.6 EXF78615.1 - 0.012 15.1 1.0 0.59 9.5 0.1 2.5 1 1 1 2 2 2 0 Myelin transcription factor 1 Lar_restr_allev PF14354.1 EXF78615.1 - 0.046 14.0 0.1 0.14 12.4 0.1 1.9 1 0 0 1 1 1 0 Restriction alleviation protein Lar DUF3621 PF12285.3 EXF78615.1 - 0.078 13.1 1.1 3.7 7.7 0.0 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3621) IER PF05760.7 EXF78615.1 - 0.58 10.0 4.1 0.8 9.5 2.8 1.3 1 0 0 1 1 1 0 Immediate early response protein (IER) Arc_trans_TRASH PF08394.5 EXF78615.1 - 1.1 9.4 6.8 1.9 8.7 0.1 2.5 1 1 1 2 2 2 0 Archaeal TRASH domain zf-HYPF PF07503.7 EXF78615.1 - 8.6 5.8 6.1 7.4 6.0 2.3 2.4 2 1 1 3 3 3 0 HypF finger MARVEL PF01284.18 EXF78617.1 - 7.5e-22 77.7 15.8 9e-22 77.4 11.0 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF1712 PF08217.6 EXF78618.1 - 7.9e-15 54.1 0.0 5.2e-13 48.1 0.0 2.4 2 1 0 2 2 2 2 Fungal domain of unknown function (DUF1712) DNA_pol_E_B PF04042.11 EXF78619.1 - 7.9e-62 208.2 0.0 1.1e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pkinase PF00069.20 EXF78621.1 - 1.4e-71 240.6 0.0 1.9e-71 240.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF78621.1 - 1.4e-32 112.7 0.0 2.2e-32 112.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase UBA_2 PF08587.6 EXF78621.1 - 6.9e-16 58.1 0.2 1.6e-15 56.9 0.2 1.7 1 0 0 1 1 1 1 Ubiquitin associated domain (UBA) Kinase-like PF14531.1 EXF78621.1 - 2.8e-05 23.2 0.0 4.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YukC PF10140.4 EXF78621.1 - 0.0061 15.1 0.0 0.011 14.3 0.0 1.3 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC RIO1 PF01163.17 EXF78621.1 - 0.0083 15.4 0.1 0.02 14.2 0.1 1.5 1 1 0 1 1 1 1 RIO1 family APH PF01636.18 EXF78621.1 - 0.035 13.8 1.1 0.36 10.5 0.2 2.4 1 1 1 2 2 2 0 Phosphotransferase enzyme family NACHT PF05729.7 EXF78622.1 - 8e-09 35.3 0.0 2.4e-08 33.8 0.0 1.9 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EXF78622.1 - 8.8e-07 29.0 0.2 4e-06 26.9 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EXF78622.1 - 1e-05 25.7 0.0 6e-05 23.1 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EXF78622.1 - 0.018 14.4 0.3 0.047 13.1 0.0 1.8 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 EXF78622.1 - 0.06 13.5 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 EXF78622.1 - 0.071 13.4 1.2 1.5 9.1 0.0 2.6 2 0 0 2 2 2 0 ABC transporter Peroxidase_2 PF01328.12 EXF78623.1 - 3.4e-27 94.9 0.0 4e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Aldo_ket_red PF00248.16 EXF78624.1 - 4.3e-65 219.3 0.0 6.8e-65 218.6 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family HTH_Tnp_Mu_2 PF09039.6 EXF78624.1 - 0.021 14.5 0.2 2.6 7.8 0.0 2.7 3 0 0 3 3 3 0 Mu DNA binding, I gamma subdomain adh_short PF00106.20 EXF78625.1 - 2.4e-17 63.3 0.1 3.6e-17 62.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF78625.1 - 1.8e-08 34.2 0.2 2.9e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF78625.1 - 8.1e-05 22.5 0.0 0.0002 21.2 0.0 1.6 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EXF78626.1 - 1.3e-18 67.2 0.0 2.2e-18 66.5 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF78626.1 - 5e-16 59.2 0.3 1.1e-15 58.1 0.2 1.6 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EXF78626.1 - 5.6e-11 41.8 0.1 8.4e-11 41.2 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EXF78626.1 - 5.5e-08 31.8 0.0 5.4e-06 25.3 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EXF78626.1 - 9.6e-07 28.2 0.0 2.1e-06 27.1 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family NAD_binding_4 PF07993.7 EXF78626.1 - 5.4e-05 22.2 0.0 0.011 14.6 0.0 2.5 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EXF78626.1 - 0.0035 16.2 1.5 0.01 14.7 0.1 2.1 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein TrkA_N PF02254.13 EXF78626.1 - 0.0068 16.3 0.0 0.022 14.7 0.0 1.8 1 0 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 EXF78626.1 - 0.036 13.0 0.0 0.053 12.5 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DapB_N PF01113.15 EXF78626.1 - 0.043 13.7 0.0 0.13 12.1 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus SNAP PF14938.1 EXF78626.1 - 0.11 11.6 0.1 0.16 11.0 0.1 1.1 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP MFS_1 PF07690.11 EXF78627.1 - 4.3e-36 124.3 19.6 6.7e-36 123.7 13.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2929 PF11151.3 EXF78627.1 - 0.069 13.2 6.1 0.09 12.8 0.0 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF2929) ESSS PF10183.4 EXF78627.1 - 6 7.3 5.7 14 6.1 0.1 3.2 2 1 1 3 3 3 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Glyco_hydro_88 PF07470.8 EXF78628.1 - 9.1e-86 287.9 1.1 1.1e-85 287.7 0.8 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 Glyco_hydro_76 PF03663.9 EXF78628.1 - 0.09 12.1 3.4 0.067 12.5 0.5 2.2 3 1 0 3 3 3 0 Glycosyl hydrolase family 76 TAFH PF07531.9 EXF78628.1 - 0.18 11.4 0.1 1.2 8.8 0.0 2.0 2 0 0 2 2 2 0 NHR1 homology to TAF MFS_1 PF07690.11 EXF78629.1 - 4.6e-38 130.8 11.0 7.7e-38 130.0 7.6 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF78629.1 - 3.4e-11 42.3 0.8 3.4e-11 42.3 0.6 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 EXF78629.1 - 7.2e-11 41.1 0.0 0.00034 19.1 2.1 3.2 1 1 1 3 3 3 3 MFS/sugar transport protein MFS_3 PF05977.8 EXF78629.1 - 0.00015 20.0 8.4 0.0015 16.7 1.7 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector BT1 PF03092.11 EXF78629.1 - 0.11 11.2 4.3 0.13 10.9 0.2 2.6 2 1 1 3 3 3 0 BT1 family Sigma70_ner PF04546.8 EXF78629.1 - 1.6 8.3 5.2 6.6 6.2 1.8 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Glyco_hydro_3 PF00933.16 EXF78631.1 - 8.7e-95 317.1 0.0 1.2e-94 316.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF78631.1 - 9.9e-55 185.5 0.0 9.5e-54 182.3 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF78631.1 - 2.3e-22 78.6 0.1 4.6e-22 77.7 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain ABC_tran PF00005.22 EXF78632.1 - 9.4e-48 161.9 0.1 6e-26 91.3 0.0 4.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EXF78632.1 - 2.2e-14 54.1 5.1 7e-07 29.4 0.3 3.9 2 2 0 3 3 3 3 AAA domain SMC_N PF02463.14 EXF78632.1 - 1e-12 47.7 0.1 6.9e-05 22.1 0.0 4.1 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EXF78632.1 - 3.7e-08 33.9 0.9 0.00086 19.6 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EXF78632.1 - 1.2e-07 31.1 0.3 0.007 15.8 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EXF78632.1 - 2.8e-07 29.8 0.0 0.00092 18.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EXF78632.1 - 5e-07 29.6 0.0 0.015 15.2 0.0 3.0 3 0 0 3 3 2 2 50S ribosome-binding GTPase AAA_22 PF13401.1 EXF78632.1 - 1.5e-06 28.3 0.0 0.13 12.4 0.0 4.0 3 0 0 3 3 3 2 AAA domain AAA_15 PF13175.1 EXF78632.1 - 2.1e-06 27.0 1.0 0.084 11.9 0.0 3.6 4 0 0 4 4 4 2 AAA ATPase domain AAA_17 PF13207.1 EXF78632.1 - 3.6e-06 27.7 2.1 0.039 14.7 0.5 3.4 3 1 0 3 3 2 2 AAA domain Chromo PF00385.19 EXF78632.1 - 5.9e-06 25.8 0.5 1.8e-05 24.2 0.3 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Miro PF08477.8 EXF78632.1 - 1.2e-05 25.7 0.1 0.04 14.3 0.1 3.3 2 1 0 2 2 2 1 Miro-like protein AAA_10 PF12846.2 EXF78632.1 - 1.4e-05 24.7 0.1 0.84 9.0 0.1 4.0 4 1 0 4 4 4 2 AAA-like domain SbcCD_C PF13558.1 EXF78632.1 - 2.5e-05 24.0 0.0 0.45 10.4 0.0 3.3 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EXF78632.1 - 0.00012 21.8 0.1 0.16 11.6 0.1 2.6 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EXF78632.1 - 0.00012 22.1 0.0 0.012 15.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EXF78632.1 - 0.00025 20.9 0.6 0.6 9.8 0.0 4.0 4 0 0 4 4 4 1 Domain of unknown function DUF87 NACHT PF05729.7 EXF78632.1 - 0.00025 20.7 0.0 0.31 10.6 0.0 2.8 2 0 0 2 2 2 1 NACHT domain CLASP_N PF12348.3 EXF78632.1 - 0.00033 20.0 0.0 0.0016 17.8 0.0 2.1 2 0 0 2 2 2 1 CLASP N terminal AAA_33 PF13671.1 EXF78632.1 - 0.00043 20.1 0.4 0.85 9.4 0.0 3.0 3 0 0 3 3 2 2 AAA domain ArgK PF03308.11 EXF78632.1 - 0.00056 18.7 0.2 0.15 10.7 0.1 2.5 2 0 0 2 2 2 1 ArgK protein AAA_18 PF13238.1 EXF78632.1 - 0.00074 19.8 0.1 0.14 12.4 0.0 3.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EXF78632.1 - 0.00076 19.6 0.0 2.1 8.5 0.0 2.6 2 0 0 2 2 2 2 RNA helicase HEAT_2 PF13646.1 EXF78632.1 - 0.0017 18.5 8.0 0.17 12.1 0.5 3.9 3 1 1 4 4 4 2 HEAT repeats AAA_25 PF13481.1 EXF78632.1 - 0.003 16.9 0.0 2.1 7.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EXF78632.1 - 0.0045 15.9 0.0 1.4 7.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EXF78632.1 - 0.0055 16.5 0.0 5.8 6.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain Septin PF00735.13 EXF78632.1 - 0.0062 15.5 0.0 1.8 7.5 0.0 2.5 2 0 0 2 2 2 1 Septin AAA_13 PF13166.1 EXF78632.1 - 0.0083 14.6 1.0 2.1 6.7 0.0 2.6 3 0 0 3 3 2 2 AAA domain AAA_30 PF13604.1 EXF78632.1 - 0.0084 15.7 0.3 5 6.6 0.1 3.2 3 0 0 3 3 2 0 AAA domain AAA PF00004.24 EXF78632.1 - 0.0085 16.2 0.0 4.4 7.5 0.0 3.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 EXF78632.1 - 0.0094 15.7 0.0 0.43 10.3 0.0 3.1 3 0 0 3 3 3 1 Dynamin family PduV-EutP PF10662.4 EXF78632.1 - 0.012 15.0 0.0 1 8.8 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FtsK_SpoIIIE PF01580.13 EXF78632.1 - 0.019 14.4 0.1 3.6 7.0 0.0 2.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family Arch_ATPase PF01637.13 EXF78632.1 - 0.025 14.2 0.0 3.7 7.1 0.0 2.7 2 0 0 2 2 2 0 Archaeal ATPase HEAT PF02985.17 EXF78632.1 - 0.028 14.4 1.5 23 5.3 0.0 4.7 4 0 0 4 4 3 0 HEAT repeat AAA_16 PF13191.1 EXF78632.1 - 0.049 13.6 3.6 3.8 7.4 0.0 3.8 3 1 0 3 3 3 0 AAA ATPase domain MutS_V PF00488.16 EXF78632.1 - 0.083 12.2 0.1 7 5.9 0.0 2.3 2 0 0 2 2 2 0 MutS domain V Arm PF00514.18 EXF78632.1 - 0.21 11.4 1.5 35 4.4 0.0 3.3 3 0 0 3 3 2 0 Armadillo/beta-catenin-like repeat Glyco_trans_2_3 PF13632.1 EXF78633.1 - 9.1e-47 159.2 7.8 9.1e-47 159.2 5.4 2.2 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EXF78633.1 - 3.2e-07 30.4 0.0 6.8e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EXF78633.1 - 1.1e-05 25.2 0.0 2.7e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EXF78633.1 - 0.002 17.4 0.0 0.0044 16.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_hydro_16 PF00722.16 EXF78634.1 - 3.9e-18 65.4 2.3 7.4e-18 64.4 1.6 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 TaqI_C PF12950.2 EXF78634.1 - 0.032 13.9 0.0 0.069 12.9 0.0 1.5 1 0 0 1 1 1 0 TaqI-like C-terminal specificity domain Arabinose_trans PF04602.7 EXF78634.1 - 0.16 10.1 0.1 0.24 9.5 0.1 1.1 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein Fasciclin PF02469.17 EXF78636.1 - 6.5e-45 152.2 0.1 4.1e-28 97.9 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain RRM_1 PF00076.17 EXF78638.1 - 8.5e-17 60.5 0.0 1.2e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF78638.1 - 1.4e-12 47.3 0.0 2.1e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF78638.1 - 2.6e-07 30.3 0.0 4e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 EXF78638.1 - 0.00015 21.5 11.3 0.00015 21.5 7.8 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) Mem_trans PF03547.13 EXF78639.1 - 1.6e-48 164.9 0.1 4.2e-48 163.5 0.1 1.6 1 1 0 1 1 1 1 Membrane transport protein Sec62 PF03839.11 EXF78640.1 - 4.1 6.7 7.2 5.8 6.2 5.0 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Pkinase PF00069.20 EXF78641.1 - 1.2e-49 168.8 0.0 2e-46 158.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EXF78641.1 - 7.7e-30 103.8 0.0 2.3e-28 99.0 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.6 EXF78641.1 - 0.00039 19.3 0.1 0.00075 18.4 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.1 EXF78641.1 - 0.0005 19.1 0.0 0.00076 18.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like SUR7 PF06687.7 EXF78642.1 - 1.4e-30 106.4 11.5 2.1e-30 105.8 8.0 1.3 1 1 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EXF78642.1 - 2.9e-05 23.8 10.6 2.9e-05 23.8 7.3 1.9 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction Trp_oprn_chp PF09534.5 EXF78642.1 - 0.00033 20.3 0.8 0.00064 19.3 0.6 1.4 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Amastin PF07344.6 EXF78642.1 - 0.4 10.2 18.1 0.028 14.0 9.1 1.5 2 0 0 2 2 2 0 Amastin surface glycoprotein Clc-like PF07062.7 EXF78642.1 - 0.89 8.7 10.3 0.035 13.3 3.4 1.4 2 0 0 2 2 2 0 Clc-like BPL_LplA_LipB PF03099.14 EXF78643.1 - 2.3e-07 30.8 0.0 3.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family DSPc PF00782.15 EXF78644.1 - 1.9e-24 85.7 0.2 2e-23 82.4 0.1 2.1 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EXF78644.1 - 0.0027 17.0 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase UAA PF08449.6 EXF78645.1 - 1.1e-69 234.6 12.5 2.7e-69 233.3 8.6 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EXF78645.1 - 7.7e-06 25.9 28.2 0.00023 21.1 5.0 3.3 3 0 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EXF78645.1 - 0.0004 19.5 4.7 0.027 13.5 0.3 2.3 2 0 0 2 2 2 2 Nucleotide-sugar transporter EmrE PF13536.1 EXF78645.1 - 0.18 12.0 22.7 0.52 10.5 5.1 3.0 3 0 0 3 3 3 0 Multidrug resistance efflux transporter Peptidase_U4 PF03419.8 EXF78645.1 - 1.3 8.0 6.3 0.54 9.2 1.8 2.0 2 0 0 2 2 2 0 Sporulation factor SpoIIGA TPT PF03151.11 EXF78645.1 - 1.3 8.6 19.3 0.026 14.1 5.7 2.4 2 1 0 2 2 2 0 Triose-phosphate Transporter family KH_1 PF00013.24 EXF78646.1 - 9.4e-37 124.4 13.6 2.2e-14 52.8 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EXF78646.1 - 8.3e-30 101.9 12.6 1.8e-11 43.3 0.5 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EXF78646.1 - 7.6e-09 35.0 9.4 0.013 15.0 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EXF78646.1 - 2.2e-08 33.6 2.1 0.052 13.2 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EXF78646.1 - 0.00032 20.4 4.7 0.67 9.7 0.1 3.3 3 0 0 3 3 3 2 NusA-like KH domain dUTPase PF00692.14 EXF78646.1 - 0.0096 15.3 0.3 0.47 9.9 0.0 2.9 3 0 0 3 3 3 1 dUTPase DEAD PF00270.24 EXF78648.1 - 3.8e-31 107.8 0.1 5.9e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF78648.1 - 2e-17 62.7 0.0 3.9e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EXF78648.1 - 3.8e-05 23.6 0.0 7.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EXF78648.1 - 0.0053 15.5 0.0 0.0081 14.9 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Dermcidin PF15291.1 EXF78649.1 - 0.0022 18.1 0.9 0.01 16.0 0.6 2.2 1 0 0 1 1 1 1 Dermcidin, antibiotic peptide TIP41 PF04176.8 EXF78650.1 - 7.7e-75 250.1 0.9 1e-74 249.7 0.6 1.1 1 0 0 1 1 1 1 TIP41-like family Pkinase PF00069.20 EXF78652.1 - 2.4e-70 236.6 0.0 3.1e-70 236.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF78652.1 - 1e-43 149.2 0.0 1.4e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF78652.1 - 1.8e-06 27.1 0.0 6.9e-06 25.2 0.0 1.9 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 EXF78652.1 - 0.00029 19.9 0.0 0.00048 19.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EXF78652.1 - 0.006 15.9 0.1 0.014 14.7 0.1 1.6 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 EXF78652.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Peptidase_M76 PF09768.4 EXF78653.1 - 5.5e-61 205.0 3.0 3.4e-60 202.4 2.1 2.0 1 1 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.4 EXF78653.1 - 0.027 14.1 0.8 0.027 14.1 0.5 2.0 1 1 1 2 2 2 0 SprT-like family AA_kinase PF00696.23 EXF78654.1 - 1.2e-38 133.0 1.4 1.8e-38 132.4 0.9 1.2 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.15 EXF78654.1 - 1.5e-14 53.4 0.3 1.1e-13 50.7 0.0 2.4 2 0 0 2 2 2 1 PUA domain BNIP3 PF06553.7 EXF78654.1 - 0.073 12.4 0.2 0.27 10.5 0.1 1.8 2 0 0 2 2 2 0 BNIP3 CLTH PF10607.4 EXF78655.1 - 6.2e-36 123.2 0.0 1e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EXF78655.1 - 0.0023 17.6 0.1 0.0068 16.1 0.0 1.9 2 0 0 2 2 2 1 LisH HLH PF00010.21 EXF78656.1 - 1.5e-12 46.9 1.0 3.1e-12 46.0 0.7 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Snapin_Pallidin PF14712.1 EXF78656.1 - 0.039 14.2 0.8 0.084 13.1 0.5 1.5 1 0 0 1 1 1 0 Snapin/Pallidin DivIC PF04977.10 EXF78656.1 - 0.35 10.3 3.4 0.76 9.3 2.3 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF2841 PF11001.3 EXF78657.1 - 4.2e-40 136.5 6.8 6.3e-40 135.9 4.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2841) GRP PF07172.6 EXF78657.1 - 2.5 8.6 7.5 6.6 7.2 5.2 1.7 1 0 0 1 1 1 0 Glycine rich protein family ABC_membrane PF00664.18 EXF78658.1 - 7.9e-91 304.2 24.0 4.6e-49 167.2 6.0 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EXF78658.1 - 1.4e-50 171.1 0.0 8e-31 107.1 0.1 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EXF78658.1 - 1.7e-09 37.2 4.4 0.004 16.4 0.1 4.2 2 2 0 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EXF78658.1 - 2.9e-05 24.0 0.0 0.32 10.9 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EXF78658.1 - 3.7e-05 24.2 0.2 0.18 12.3 0.0 3.2 3 0 0 3 3 2 2 Miro-like protein AAA_16 PF13191.1 EXF78658.1 - 7.6e-05 22.7 0.1 0.12 12.2 0.1 3.1 3 0 0 3 3 3 2 AAA ATPase domain DUF258 PF03193.11 EXF78658.1 - 0.00018 20.7 0.1 0.16 11.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EXF78658.1 - 0.0007 19.0 0.1 0.39 10.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EXF78658.1 - 0.0009 18.7 0.1 0.81 9.2 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.1 EXF78658.1 - 0.002 18.1 0.0 8.7 6.2 0.0 4.2 4 0 0 4 4 4 0 AAA domain AAA_23 PF13476.1 EXF78658.1 - 0.0022 18.3 1.6 0.45 10.7 0.0 3.5 4 0 0 4 4 4 1 AAA domain Dynamin_N PF00350.18 EXF78658.1 - 0.0022 17.8 3.1 0.077 12.8 0.0 3.0 3 0 0 3 3 3 1 Dynamin family UPF0093 PF03653.8 EXF78658.1 - 0.003 17.5 0.5 0.003 17.5 0.4 2.5 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0093) RseC_MucC PF04246.7 EXF78658.1 - 0.018 14.6 0.1 0.3 10.6 0.0 3.0 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC FtsK_SpoIIIE PF01580.13 EXF78658.1 - 0.033 13.6 0.2 6.3 6.2 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EXF78658.1 - 0.093 13.5 0.1 4 8.2 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EXF78658.1 - 0.1 12.3 3.1 0.86 9.3 0.1 2.7 3 0 0 3 3 2 0 Domain of unknown function DUF87 AIG1 PF04548.11 EXF78658.1 - 0.2 10.7 0.8 4.6 6.2 0.0 2.4 2 0 0 2 2 2 0 AIG1 family NACHT PF05729.7 EXF78658.1 - 0.22 11.1 0.8 0.8 9.3 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.1 EXF78658.1 - 0.37 10.9 1.8 32 4.6 0.0 3.3 2 1 0 2 2 2 0 AAA domain DUF3763 PF12592.3 EXF78659.1 - 0.097 12.3 0.5 0.32 10.6 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3763) SIN1 PF05422.7 EXF78662.1 - 9.1e-35 120.1 0.0 3.8e-18 65.2 0.0 3.0 3 0 0 3 3 3 2 Stress-activated map kinase interacting protein 1 (SIN1) TUG-UBL1 PF11470.3 EXF78662.1 - 0.0058 16.5 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 GLUT4 regulating protein TUG PRCC PF10253.4 EXF78663.1 - 1.1e-40 140.3 3.9 1.1e-40 140.3 2.7 2.9 3 0 0 3 3 3 1 Mitotic checkpoint regulator, MAD2B-interacting AMIN PF11741.3 EXF78663.1 - 0.079 12.9 0.1 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 AMIN domain UCH PF00443.24 EXF78665.1 - 4.4e-45 153.8 0.0 1.1e-44 152.5 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUF3517 PF12030.3 EXF78665.1 - 6.4e-20 70.9 0.4 1.3e-19 69.9 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3517) UCH_1 PF13423.1 EXF78665.1 - 1.9e-16 60.4 0.0 4.1e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pox_A3L PF05288.6 EXF78665.1 - 0.051 13.3 1.0 0.12 12.1 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A3L Protein DUF1387 PF07139.6 EXF78665.1 - 7.7 6.0 8.0 14 5.1 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) RNase_P_pop3 PF08228.6 EXF78666.1 - 5.7e-08 32.7 0.0 1.1e-05 25.3 0.0 2.2 2 0 0 2 2 2 2 RNase P subunit Pop3 NOC3p PF07540.6 EXF78668.1 - 1.3e-31 108.7 2.0 6.4e-31 106.4 0.1 3.0 3 0 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.12 EXF78668.1 - 5.2e-25 87.8 0.5 2.7e-24 85.4 0.1 2.2 2 0 0 2 2 2 1 CBF/Mak21 family RRN3 PF05327.6 EXF78668.1 - 0.017 13.2 0.2 0.017 13.2 0.1 2.3 2 1 1 3 3 3 0 RNA polymerase I specific transcription initiation factor RRN3 CENP-B_dimeris PF09026.5 EXF78668.1 - 0.21 11.8 14.4 0.031 14.5 2.4 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain UPF0113 PF03657.8 EXF78669.1 - 9.3e-08 31.8 0.0 1.3e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0113) Nol1_Nop2_Fmu_2 PF13636.1 EXF78669.1 - 0.072 13.1 0.0 0.24 11.4 0.0 1.9 1 1 1 2 2 2 0 pre-rRNA processing and ribosome biogenesis PUA PF01472.15 EXF78669.1 - 0.096 12.4 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 PUA domain Glyco_trans_2_3 PF13632.1 EXF78670.1 - 3.2e-46 157.4 5.1 8.9e-46 156.0 3.5 1.7 1 0 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EXF78670.1 - 1.4e-08 34.8 0.1 9.6e-08 32.0 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EXF78670.1 - 1.8e-05 24.4 0.0 5.9e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EXF78670.1 - 8.2e-05 21.9 0.0 0.00016 20.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 21 Pro-kuma_activ PF09286.6 EXF78672.1 - 7.4e-39 133.0 0.1 1.6e-38 131.9 0.0 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EXF78672.1 - 6.8e-07 28.7 0.1 1.3e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Subtilase family BBP1_C PF15272.1 EXF78674.1 - 9 5.7 9.6 0.058 12.9 0.3 1.9 2 0 0 2 2 2 0 Spindle pole body component BBP1, C-terminal Methyltransf_18 PF12847.2 EXF78676.1 - 1.7e-19 70.4 0.1 2.7e-19 69.7 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF78676.1 - 3.7e-14 52.5 0.0 4.8e-12 45.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF78676.1 - 3.3e-09 36.8 0.0 8.9e-09 35.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF78676.1 - 5e-09 36.0 0.1 2.6e-08 33.7 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF78676.1 - 2.5e-08 34.3 0.0 7.6e-08 32.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF78676.1 - 2.1e-06 28.1 1.1 3.5e-05 24.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.1 EXF78676.1 - 1.1e-05 25.0 0.0 1.5e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF78676.1 - 3.1e-05 24.2 0.0 7.9e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain AdoMet_MTase PF07757.8 EXF78676.1 - 0.00024 21.1 0.0 0.00043 20.3 0.0 1.4 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase MTS PF05175.9 EXF78676.1 - 0.00054 19.3 0.0 0.00095 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 EXF78676.1 - 0.0044 16.4 0.0 0.0075 15.6 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.8 EXF78676.1 - 0.0072 15.4 0.0 0.01 15.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EXF78676.1 - 0.0082 15.2 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 EXF78676.1 - 0.022 14.7 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase HrpB1_HrpK PF09613.5 EXF78676.1 - 0.036 13.5 0.3 0.059 12.8 0.2 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) TehB PF03848.9 EXF78676.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB HEAT PF02985.17 EXF78677.1 - 8e-45 146.9 17.5 0.0029 17.5 0.1 13.2 14 0 0 14 14 14 12 HEAT repeat HEAT_2 PF13646.1 EXF78677.1 - 1.4e-31 108.5 2.5 2.3e-08 34.2 0.0 7.7 3 3 5 8 8 8 7 HEAT repeats Vac14_Fab1_bd PF12755.2 EXF78677.1 - 3.5e-11 43.3 5.5 0.043 14.1 0.1 7.9 5 1 3 9 9 9 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EXF78677.1 - 9.8e-10 38.6 13.1 0.0089 16.4 0.0 8.5 8 2 2 10 10 10 2 HEAT-like repeat Adaptin_N PF01602.15 EXF78677.1 - 2.8e-07 29.2 10.7 0.0013 17.2 0.1 5.1 2 1 1 4 4 4 3 Adaptin N terminal region CLASP_N PF12348.3 EXF78677.1 - 8.2e-05 22.0 2.6 0.99 8.7 0.1 4.9 2 2 3 5 5 5 2 CLASP N terminal DUF2435 PF10363.4 EXF78677.1 - 0.00012 21.9 4.1 0.11 12.3 0.1 4.7 4 1 1 5 5 5 1 Protein of unknown function (DUF2435) RIX1 PF08167.7 EXF78677.1 - 0.006 16.2 0.4 0.45 10.1 0.0 3.8 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis Cnd3 PF12719.2 EXF78677.1 - 0.0065 15.4 1.0 0.036 13.0 0.2 2.5 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Cnd1 PF12717.2 EXF78677.1 - 0.046 13.5 7.2 8.2 6.2 0.0 5.6 3 1 2 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Proteasom_PSMB PF10508.4 EXF78677.1 - 0.091 11.0 3.9 0.46 8.7 0.1 2.9 3 0 0 3 3 3 0 Proteasome non-ATPase 26S subunit Arm PF00514.18 EXF78677.1 - 0.13 12.1 5.9 14 5.7 0.0 5.3 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat B3_4 PF03483.12 EXF78678.1 - 6.3e-27 94.1 0.1 1e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EXF78678.1 - 1.2e-17 63.4 0.0 2.7e-14 52.7 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetase B5 domain tRNA-synt_2d PF01409.15 EXF78678.1 - 0.057 12.6 0.0 0.69 9.0 0.0 2.1 1 1 0 1 1 1 0 tRNA synthetases class II core domain (F) Myotub-related PF06602.9 EXF78680.1 - 2.5e-126 421.2 0.1 3.4e-126 420.7 0.1 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 EXF78680.1 - 0.0032 16.8 0.0 0.0057 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EXF78680.1 - 0.023 14.9 0.0 0.06 13.6 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family Ribosomal_S3_C PF00189.15 EXF78681.1 - 1.2e-16 60.6 0.1 2.4e-16 59.6 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EXF78681.1 - 2.7e-12 46.0 0.1 4.6e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 KH domain UN_NPL4 PF11543.3 EXF78681.1 - 0.059 13.6 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Mg_trans_NIPA PF05653.9 EXF78682.1 - 1.7e-103 345.7 13.3 2.2e-103 345.3 9.2 1.0 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EXF78682.1 - 8e-07 29.2 3.9 8e-07 29.2 2.7 3.2 2 1 0 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EXF78682.1 - 0.00036 20.5 7.2 0.00036 20.5 5.0 3.2 3 1 1 4 4 4 1 EamA-like transporter family DUF4131 PF13567.1 EXF78682.1 - 1.7 8.0 5.5 1.4 8.3 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2420 PF10336.4 EXF78683.1 - 1.8e-06 27.5 0.0 4.2e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2420) Adap_comp_sub PF00928.16 EXF78684.1 - 4.8e-17 61.9 0.1 7.7e-17 61.2 0.1 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EXF78684.1 - 2.9e-08 33.5 0.1 4.9e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.4 EXF78684.1 - 0.0043 16.2 0.0 0.013 14.6 0.0 1.8 1 1 0 1 1 1 1 Muniscin C-terminal mu homology domain DUF3484 PF11983.3 EXF78684.1 - 0.035 14.9 0.1 0.15 12.8 0.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3484) Apc4 PF12896.2 EXF78685.1 - 1.1e-47 162.0 0.0 1.7e-47 161.4 0.0 1.2 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 WD40 PF00400.27 EXF78685.1 - 0.086 12.7 0.0 0.3 11.0 0.0 2.0 1 0 0 1 1 1 0 WD domain, G-beta repeat Gtr1_RagA PF04670.7 EXF78686.1 - 1e-70 237.5 0.1 1.2e-70 237.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EXF78686.1 - 1e-05 25.9 0.0 0.0016 18.8 0.0 2.3 2 0 0 2 2 2 2 Miro-like protein MIF PF01187.13 EXF78687.1 - 5e-10 39.4 0.0 9.5e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) Cation_efflux PF01545.16 EXF78688.1 - 0.026 13.5 5.0 0.034 13.2 3.5 1.3 1 0 0 1 1 1 0 Cation efflux family PSI_8 PF00796.13 EXF78688.1 - 0.045 13.3 1.3 0.16 11.6 0.9 2.0 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VIII Voltage_CLC PF00654.15 EXF78690.1 - 2.9e-89 299.5 27.5 2.9e-89 299.5 19.1 1.4 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EXF78690.1 - 0.00031 20.4 0.0 0.015 15.0 0.0 2.5 2 0 0 2 2 2 1 CBS domain Neurochondrin PF05536.6 EXF78691.1 - 2.8e-96 322.9 0.0 3.5e-96 322.6 0.0 1.0 1 0 0 1 1 1 1 Neurochondrin RIX1 PF08167.7 EXF78691.1 - 0.058 13.0 0.1 0.88 9.2 0.0 2.7 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis Nop14 PF04147.7 EXF78692.1 - 0.0011 16.9 6.0 0.0016 16.4 4.2 1.4 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 EXF78692.1 - 0.0044 15.1 7.3 0.0052 14.8 5.0 1.1 1 0 0 1 1 1 1 CDC45-like protein DUF3449 PF11931.3 EXF78692.1 - 0.047 13.2 2.9 0.097 12.1 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) Foamy_virus_ENV PF03408.9 EXF78692.1 - 0.068 10.6 0.0 0.089 10.3 0.0 1.1 1 0 0 1 1 1 0 Foamy virus envelope protein Herpes_DNAp_acc PF04929.7 EXF78692.1 - 1.3 7.8 6.6 2.2 7.1 4.6 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor SAPS PF04499.10 EXF78692.1 - 1.6 7.3 5.3 1.9 7.0 3.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Atg14 PF10186.4 EXF78692.1 - 2.3 7.0 7.6 3.3 6.5 5.3 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SRRM_C PF15230.1 EXF78692.1 - 3.5 7.7 6.0 0.89 9.6 0.8 2.2 2 0 0 2 2 2 0 Serine/arginine repetitive matrix protein C-terminus YqfQ PF14181.1 EXF78692.1 - 7.3 6.6 12.4 0.48 10.4 5.2 1.6 2 0 0 2 2 2 0 YqfQ-like protein Ras PF00071.17 EXF78693.1 - 1.9e-52 176.9 0.0 2.2e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EXF78693.1 - 5e-16 59.2 0.0 1.2e-15 58.0 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EXF78693.1 - 1.3e-06 27.7 0.0 1.8e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Arginase PF00491.16 EXF78694.1 - 2.6e-92 309.0 0.0 3.1e-92 308.8 0.0 1.0 1 0 0 1 1 1 1 Arginase family UPF0489 PF12640.2 EXF78694.1 - 0.017 15.3 1.4 0.13 12.4 0.2 2.1 1 1 1 2 2 2 0 UPF0489 domain tRNA-synt_2 PF00152.15 EXF78695.1 - 3e-69 233.3 0.1 5.5e-69 232.4 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EXF78695.1 - 1.5e-10 40.7 0.0 2.8e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain SPOUT_MTase PF02590.12 EXF78695.1 - 0.015 15.0 1.3 0.028 14.1 0.9 1.4 1 0 0 1 1 1 0 Predicted SPOUT methyltransferase tRNA_anti_2 PF13742.1 EXF78695.1 - 0.073 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain RRM_6 PF14259.1 EXF78696.1 - 5.4e-39 132.0 0.1 1.5e-09 37.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EXF78696.1 - 4.6e-36 122.2 0.1 5.3e-11 42.0 0.1 4.5 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF78696.1 - 1.8e-19 69.3 1.7 0.00014 21.6 0.0 4.9 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM PF10378.4 EXF78696.1 - 1e-13 50.6 6.2 1e-13 50.6 4.3 3.4 3 1 0 3 3 3 1 Putative RRM domain RRM_3 PF08777.6 EXF78696.1 - 0.00053 19.7 0.1 0.024 14.4 0.1 2.6 2 0 0 2 2 2 1 RNA binding motif RNA_bind PF08675.6 EXF78696.1 - 0.0071 16.3 0.1 0.047 13.6 0.0 2.4 3 0 0 3 3 3 1 RNA binding domain DUF4523 PF15023.1 EXF78696.1 - 0.039 13.4 0.0 1.1 8.7 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) Nup35_RRM_2 PF14605.1 EXF78696.1 - 0.093 12.5 0.0 5.8 6.7 0.0 3.2 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif zf-C2H2 PF00096.21 EXF78697.1 - 8.6e-28 94.9 47.2 0.00039 20.5 0.5 10.4 10 0 0 10 10 10 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF78697.1 - 1.1e-23 81.7 46.7 0.00065 19.8 0.4 10.2 10 0 0 10 10 10 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EXF78697.1 - 3.1e-16 58.7 44.2 0.00032 20.8 1.0 11.0 11 1 0 11 11 11 4 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EXF78697.1 - 3.2e-07 30.2 26.9 2.1 8.6 0.0 10.0 11 0 0 11 11 11 4 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EXF78697.1 - 8.3e-05 22.6 19.7 0.083 13.1 0.0 8.3 9 0 0 9 9 9 1 Zinc-finger of C2H2 type DUF4187 PF13821.1 EXF78697.1 - 0.0039 16.7 2.1 0.0088 15.6 0.1 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4187) Ogr_Delta PF04606.7 EXF78697.1 - 0.31 10.7 14.2 1.4 8.6 0.2 5.0 4 1 2 6 6 6 0 Ogr/Delta-like zinc finger RNA_pol_Rpb6 PF01192.17 EXF78698.1 - 1.3e-24 85.6 0.3 2e-24 85.1 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 Tyrosinase PF00264.15 EXF78699.1 - 2.9e-43 148.5 0.4 2.9e-43 148.5 0.3 1.4 2 0 0 2 2 2 1 Common central domain of tyrosinase Med10 PF09748.4 EXF78700.1 - 9.9e-40 135.3 0.0 1.1e-39 135.1 0.0 1.0 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex DUF3877 PF12993.2 EXF78700.1 - 0.037 13.6 0.0 0.068 12.7 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) DUF2408 PF10303.4 EXF78700.1 - 0.15 12.1 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) TPR_11 PF13414.1 EXF78701.1 - 8.2e-48 159.9 22.7 1.6e-17 62.9 3.6 6.3 4 2 2 6 6 6 5 TPR repeat TPR_1 PF00515.23 EXF78701.1 - 4.8e-37 124.0 17.3 8.5e-07 28.3 0.1 8.3 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.12 EXF78701.1 - 1.4e-35 118.3 15.5 1.9e-06 27.3 0.0 8.2 8 0 0 8 8 8 7 Tetratricopeptide repeat DnaJ PF00226.26 EXF78701.1 - 3.8e-28 97.0 8.9 6.2e-28 96.3 2.8 2.9 3 0 0 3 3 2 1 DnaJ domain TPR_16 PF13432.1 EXF78701.1 - 3.8e-23 81.5 8.1 2.7e-05 24.7 0.1 6.2 4 2 2 6 6 6 5 Tetratricopeptide repeat TPR_19 PF14559.1 EXF78701.1 - 1.6e-21 76.4 14.7 2e-05 24.8 0.0 6.0 4 2 2 6 6 5 5 Tetratricopeptide repeat TPR_14 PF13428.1 EXF78701.1 - 3.5e-18 64.4 8.6 0.00015 22.0 0.0 7.7 3 3 5 8 8 8 5 Tetratricopeptide repeat Apc3 PF12895.2 EXF78701.1 - 1e-17 64.0 6.3 4.4e-09 36.3 0.2 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EXF78701.1 - 3.3e-17 61.1 11.6 0.0015 18.5 0.0 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.1 EXF78701.1 - 3.9e-13 49.1 16.3 0.00046 20.0 0.1 5.8 4 2 2 6 6 5 5 Tetratricopeptide repeat TPR_8 PF13181.1 EXF78701.1 - 4.9e-13 47.8 19.7 0.0021 17.7 0.0 8.2 7 2 2 9 9 8 4 Tetratricopeptide repeat TPR_9 PF13371.1 EXF78701.1 - 6.8e-12 45.0 6.0 0.033 14.0 0.0 5.0 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.1 EXF78701.1 - 1.4e-10 40.1 8.2 0.36 10.7 0.0 7.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.1 EXF78701.1 - 5.2e-07 29.7 15.6 0.041 14.3 0.0 8.2 8 1 0 8 8 8 1 Tetratricopeptide repeat TPR_15 PF13429.1 EXF78701.1 - 7.8e-05 21.8 9.2 0.22 10.5 0.0 4.7 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_4 PF07721.9 EXF78701.1 - 0.00095 19.3 1.4 0.11 13.0 0.0 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat NARP1 PF12569.3 EXF78701.1 - 0.0018 17.1 6.0 0.0027 16.5 0.4 3.1 2 1 0 3 3 3 1 NMDA receptor-regulated protein 1 TPR_20 PF14561.1 EXF78701.1 - 0.0058 16.7 8.1 4.3 7.5 0.0 5.1 3 3 2 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EXF78701.1 - 0.0086 15.9 2.6 18 5.4 0.0 4.6 4 1 0 4 4 4 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EXF78701.1 - 0.015 15.5 5.2 8.7 6.5 0.0 4.0 3 1 1 4 4 3 0 Alkyl sulfatase dimerisation ChAPs PF09295.5 EXF78701.1 - 0.017 13.8 0.0 0.031 13.0 0.0 1.3 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) PPR PF01535.15 EXF78701.1 - 0.035 14.0 0.3 11 6.2 0.0 3.7 4 0 0 4 4 2 0 PPR repeat Fis1_TPR_C PF14853.1 EXF78701.1 - 0.05 13.4 4.0 5.1 7.0 0.0 4.2 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat DUF928 PF06051.7 EXF78701.1 - 0.073 12.6 0.5 0.16 11.5 0.3 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) EF-hand_6 PF13405.1 EXF78702.1 - 3.6e-13 48.1 0.2 4.5e-06 26.1 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EXF78702.1 - 1.6e-10 39.5 1.4 0.00029 19.9 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EXF78702.1 - 2.5e-09 37.1 3.0 6.3e-07 29.4 0.3 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EXF78702.1 - 2.5e-07 29.7 4.9 0.00032 19.9 0.5 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EXF78702.1 - 5.6e-06 25.8 1.4 0.0089 15.6 0.1 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 EXF78702.1 - 0.011 15.6 0.0 2.8 7.8 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain Afi1 PF07792.7 EXF78703.1 - 1.6e-64 216.3 0.0 3.1e-64 215.3 0.0 1.5 1 0 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EXF78703.1 - 3.5e-36 123.3 0.0 6.6e-36 122.4 0.0 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EXF78703.1 - 5.8e-08 31.6 0.0 0.012 14.1 0.0 3.9 3 1 0 4 4 4 2 Transport protein Avl9 DUF2347 PF09804.4 EXF78703.1 - 0.012 14.8 0.0 0.068 12.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Peripla_BP_6 PF13458.1 EXF78703.1 - 0.092 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein DUF605 PF04652.11 EXF78703.1 - 0.2 11.0 11.2 0.31 10.3 7.8 1.4 1 0 0 1 1 1 0 Vta1 like Esterase PF00756.15 EXF78704.1 - 4.6e-53 180.2 0.0 5.3e-53 180.0 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 EXF78704.1 - 2.1e-06 27.8 0.0 2.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EXF78704.1 - 5.1e-06 25.8 0.1 3.6e-05 23.1 0.1 2.0 1 1 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 EXF78704.1 - 1.1e-05 25.2 0.0 1.4e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF78704.1 - 0.0039 16.4 0.0 0.0072 15.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Chlorophyllase2 PF12740.2 EXF78704.1 - 0.0046 15.8 0.0 0.0071 15.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.11 EXF78704.1 - 0.019 14.4 0.0 0.03 13.7 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Lipase_3 PF01764.20 EXF78704.1 - 0.033 13.7 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase PF07224.6 EXF78704.1 - 0.059 12.1 0.0 0.14 10.8 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase PAF-AH_p_II PF03403.8 EXF78704.1 - 0.065 11.5 0.0 0.11 10.7 0.0 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II PGAP1 PF07819.8 EXF78704.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Zip PF02535.17 EXF78706.1 - 3.9e-36 124.6 14.3 1.7e-35 122.5 9.9 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter DUF2090 PF09863.4 EXF78706.1 - 0.13 11.0 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2090) Endonuclease_NS PF01223.18 EXF78707.1 - 5.2e-60 202.6 0.0 6.6e-60 202.2 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease WD40 PF00400.27 EXF78708.1 - 3.7e-49 162.9 25.3 2.4e-08 33.5 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EXF78708.1 - 0.056 13.1 0.0 2.4 7.8 0.0 2.7 1 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A MBOAT PF03062.14 EXF78709.1 - 7.3e-19 68.0 19.0 1.1e-18 67.4 13.2 1.2 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EXF78709.1 - 0.0028 17.6 1.8 0.0077 16.2 1.3 1.8 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family ICMT PF04140.9 EXF78710.1 - 1.1e-27 96.0 1.1 2.2e-27 95.0 0.7 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EXF78710.1 - 3.2e-15 56.1 4.0 3.2e-15 56.1 2.8 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 EXF78710.1 - 0.00035 19.9 0.8 0.00049 19.4 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 EXF78710.1 - 0.0031 17.2 3.8 0.0034 17.1 2.0 1.6 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Mito_carr PF00153.22 EXF78711.1 - 2.4e-45 152.1 9.2 4.6e-17 61.5 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.13 EXF78712.1 - 5.6e-27 94.2 0.0 2.2e-25 89.0 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF78712.1 - 1.5e-08 34.3 9.4 2.8e-08 33.5 6.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 EXF78715.1 - 1.7e-72 244.4 0.0 2e-72 244.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ISN1 PF06437.6 EXF78716.1 - 1e-178 594.2 0.0 1.2e-178 594.0 0.0 1.0 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase DUF3175 PF11373.3 EXF78716.1 - 0.012 15.6 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3175) APG6 PF04111.7 EXF78717.1 - 5.1 6.0 7.2 8 5.3 5.0 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Pkinase PF00069.20 EXF78719.1 - 5.6e-55 186.2 0.0 8.2e-55 185.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF78719.1 - 1.8e-26 92.7 0.1 1.1e-25 90.1 0.1 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF78719.1 - 0.18 10.7 0.0 0.32 9.9 0.0 1.3 1 0 0 1 1 1 0 Kinase-like SUR7 PF06687.7 EXF78722.1 - 8e-35 120.3 14.4 1.1e-34 119.9 10.0 1.2 1 0 0 1 1 1 1 SUR7/PalI family DUF3353 PF11833.3 EXF78722.1 - 3.4 7.0 7.8 7.6 5.9 5.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) adh_short_C2 PF13561.1 EXF78723.1 - 4.4e-27 95.3 0.0 5.5e-27 95.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EXF78723.1 - 3.8e-25 88.7 0.1 4.9e-25 88.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF78723.1 - 4.4e-06 26.4 0.1 9.9e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF78723.1 - 0.06 12.7 0.0 0.097 12.0 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family GST_C_3 PF14497.1 EXF78726.1 - 0.0026 18.1 0.0 0.0043 17.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EXF78726.1 - 0.0078 16.0 0.0 0.024 14.5 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF3433 PF11915.3 EXF78727.1 - 3e-42 142.7 13.9 8.5e-25 86.7 0.6 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) TRP PF06011.7 EXF78728.1 - 5.3e-153 509.6 35.0 6.6e-153 509.3 24.2 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EXF78728.1 - 3.6e-42 143.7 0.7 5.9e-42 143.0 0.5 1.4 1 0 0 1 1 1 1 ML-like domain gpUL132 PF11359.3 EXF78728.1 - 0.095 12.0 0.0 0.23 10.7 0.0 1.6 1 0 0 1 1 1 0 Glycoprotein UL132 DHO_dh PF01180.16 EXF78731.1 - 1.2e-17 63.7 0.0 6e-17 61.5 0.0 1.8 1 1 0 1 1 1 1 Dihydroorotate dehydrogenase NMO PF03060.10 EXF78731.1 - 0.047 12.8 3.3 0.08 12.0 2.3 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase His_biosynth PF00977.16 EXF78731.1 - 0.059 12.6 0.2 0.09 12.0 0.1 1.2 1 0 0 1 1 1 0 Histidine biosynthesis protein MFS_1 PF07690.11 EXF78732.1 - 1.7e-12 46.7 35.2 1.2e-10 40.6 11.6 4.5 3 2 1 4 4 4 3 Major Facilitator Superfamily HSP70 PF00012.15 EXF78735.1 - 2.7e-225 748.9 7.4 3e-225 748.7 5.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EXF78735.1 - 4e-16 58.5 0.2 3.6e-15 55.3 0.0 2.0 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EXF78735.1 - 0.0047 16.5 0.0 0.0085 15.7 0.0 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 EXF78735.1 - 0.0061 15.4 0.5 0.021 13.6 0.1 2.0 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain IF4E PF01652.13 EXF78737.1 - 3.8e-59 198.9 0.0 4.8e-59 198.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E AMP-binding PF00501.23 EXF78738.1 - 8.4e-73 245.1 0.4 8.3e-72 241.8 0.3 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EXF78738.1 - 1.4e-11 45.1 0.2 2.9e-11 44.1 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Collagen PF01391.13 EXF78738.1 - 0.037 13.5 0.6 0.078 12.5 0.4 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) BolA PF01722.13 EXF78739.1 - 4.1e-27 93.9 1.6 7.1e-27 93.1 1.1 1.3 1 0 0 1 1 1 1 BolA-like protein PIP5K PF01504.13 EXF78741.1 - 1.3e-55 188.2 0.0 2.6e-55 187.2 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EXF78741.1 - 3.1e-24 85.4 0.0 4.7e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FYVE PF01363.16 EXF78741.1 - 2e-13 50.0 11.1 4.8e-13 48.8 7.7 1.7 1 0 0 1 1 1 1 FYVE zinc finger DUF2404 PF10296.4 EXF78741.1 - 0.0074 16.3 0.0 0.036 14.1 0.0 2.1 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) VPS28 PF03997.7 EXF78742.1 - 3.3e-55 186.6 0.1 3.7e-55 186.4 0.1 1.0 1 0 0 1 1 1 1 VPS28 protein Plectin PF00681.15 EXF78742.1 - 0.024 14.1 0.0 0.056 12.9 0.0 1.7 1 0 0 1 1 1 0 Plectin repeat GvpG PF05120.7 EXF78742.1 - 0.024 14.4 3.3 0.18 11.6 0.2 2.2 2 0 0 2 2 2 0 Gas vesicle protein G Noc2 PF03715.8 EXF78743.1 - 6.1e-120 399.6 0.2 6.1e-120 399.6 0.2 2.0 2 0 0 2 2 2 1 Noc2p family TFIIA PF03153.8 EXF78743.1 - 5.2e-05 23.3 9.0 5.2e-05 23.3 6.2 2.8 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit adh_short PF00106.20 EXF78743.1 - 0.17 11.8 0.3 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 short chain dehydrogenase DUF726 PF05277.7 EXF78744.1 - 2e-113 378.8 0.1 2.7e-113 378.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Abhydrolase_6 PF12697.2 EXF78744.1 - 2.4e-05 24.3 0.1 6.2e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EXF78744.1 - 0.00016 22.0 0.0 0.00031 21.0 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_5 PF12695.2 EXF78744.1 - 0.00057 19.6 0.0 0.0016 18.2 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family PE-PPE PF08237.6 EXF78744.1 - 0.059 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain Cutinase PF01083.17 EXF78744.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Cutinase Lipase_3 PF01764.20 EXF78744.1 - 0.1 12.2 0.0 0.65 9.5 0.0 2.1 2 0 0 2 2 2 0 Lipase (class 3) DUF1656 PF07869.7 EXF78746.1 - 0.24 11.1 2.7 0.44 10.3 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1656) Bromodomain PF00439.20 EXF78747.1 - 6.2e-26 90.1 0.4 1.2e-25 89.1 0.3 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EXF78747.1 - 1.9e-09 37.5 0.1 4.3e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EXF78747.1 - 4.9e-09 36.1 0.0 1.1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EXF78747.1 - 0.08 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Rad1 PF02144.11 EXF78748.1 - 5.9e-75 251.5 0.0 7e-75 251.3 0.0 1.1 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Herpes_capsid PF06112.6 EXF78749.1 - 6.8 6.7 11.2 8.2 6.4 7.8 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein S1FA PF04689.8 EXF78750.1 - 0.16 11.8 0.5 0.44 10.4 0.4 1.7 1 0 0 1 1 1 0 DNA binding protein S1FA Zn_clus PF00172.13 EXF78751.1 - 1.1e-06 28.4 10.2 2.3e-06 27.4 7.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRN7 PF11781.3 EXF78751.1 - 0.069 12.6 2.3 0.17 11.3 1.6 1.7 1 0 0 1 1 1 0 RNA polymerase I-specific transcription initiation factor Rrn7 BAGE PF08180.6 EXF78751.1 - 0.098 12.4 0.2 0.26 11.0 0.1 1.7 1 0 0 1 1 1 0 B melanoma antigen family MFS_1 PF07690.11 EXF78752.1 - 4.7e-38 130.8 65.1 4.7e-38 130.8 45.1 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EXF78752.1 - 1e-12 47.0 33.4 2e-12 46.0 23.1 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EXF78752.1 - 1.1e-11 43.9 16.2 1.1e-11 43.9 11.2 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter DUF1772 PF08592.6 EXF78755.1 - 2.6e-24 85.5 6.2 3.5e-24 85.1 4.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Acetyltransf_3 PF13302.1 EXF78756.1 - 1.6e-36 125.5 0.0 2.1e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EXF78756.1 - 0.0027 17.5 0.0 2.7 7.8 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.5 EXF78756.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Fungal_trans PF04082.13 EXF78757.1 - 5.5e-21 74.6 0.0 9e-21 73.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF78757.1 - 3.6e-08 33.1 15.2 5.4e-08 32.6 10.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_60s PF00428.14 EXF78757.1 - 0.0026 18.1 10.2 0.0026 18.1 7.0 3.9 4 0 0 4 4 4 1 60s Acidic ribosomal protein DUF4349 PF14257.1 EXF78757.1 - 5.4 6.1 8.8 63 2.6 5.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) Ribosomal_L18ae PF01775.12 EXF78758.1 - 1.3e-57 193.0 0.4 1.6e-57 192.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain PCI PF01399.22 EXF78759.1 - 1.6e-10 41.1 0.0 5.1e-10 39.5 0.0 1.9 2 0 0 2 2 2 1 PCI domain TPR_11 PF13414.1 EXF78759.1 - 0.001 18.6 0.1 0.0042 16.6 0.0 2.0 2 0 0 2 2 2 1 TPR repeat BTB PF00651.26 EXF78760.1 - 1.4e-06 28.2 0.0 4.5e-06 26.6 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Abhydrolase_5 PF12695.2 EXF78761.1 - 4.7e-10 39.4 0.0 7.7e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF78761.1 - 2.2e-09 37.5 0.6 8.5e-09 35.6 0.4 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EXF78761.1 - 0.00042 19.9 0.0 0.00089 18.8 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold LRR_4 PF12799.2 EXF78762.1 - 1.1e-42 142.9 42.0 1.6e-11 43.5 0.3 6.9 2 2 7 9 9 9 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EXF78762.1 - 3.5e-23 81.1 39.0 6.8e-08 32.1 0.8 5.2 2 1 4 6 6 6 5 Leucine rich repeat LRR_6 PF13516.1 EXF78762.1 - 1.1e-14 52.7 16.9 0.49 10.6 0.1 10.5 8 3 3 11 11 11 4 Leucine Rich repeat LRR_1 PF00560.28 EXF78762.1 - 5.9e-14 49.9 20.0 1.3 9.2 0.0 11.5 12 0 0 12 12 12 3 Leucine Rich Repeat LRR_7 PF13504.1 EXF78762.1 - 4e-11 41.2 14.2 0.38 11.1 0.0 10.0 10 0 0 10 10 10 3 Leucine rich repeat LRR_9 PF14580.1 EXF78762.1 - 2e-09 37.2 9.5 0.00072 19.1 1.4 3.3 1 1 2 3 3 3 3 Leucine-rich repeat Aldo_ket_red PF00248.16 EXF78763.1 - 5e-48 163.3 0.0 5.7e-48 163.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pkinase PF00069.20 EXF78764.1 - 1.2e-11 44.2 0.0 2e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EXF78764.1 - 1.4e-09 37.3 0.0 0.015 14.3 0.0 3.2 3 0 0 3 3 3 3 Protein tyrosine kinase ABC_membrane_2 PF06472.10 EXF78766.1 - 7.3e-99 330.4 2.2 4.2e-98 327.9 0.1 2.5 3 0 0 3 3 3 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EXF78766.1 - 1.2e-16 61.1 0.0 3.3e-16 59.8 0.0 1.7 2 0 0 2 2 2 1 ABC transporter AAA_17 PF13207.1 EXF78766.1 - 0.0017 19.1 0.9 0.0069 17.1 0.1 2.3 1 1 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EXF78766.1 - 0.0044 17.0 0.1 0.012 15.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain ALIX_LYPXL_bnd PF13949.1 EXF78766.1 - 0.0073 15.2 0.1 0.018 14.0 0.0 1.6 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV AAA PF00004.24 EXF78766.1 - 0.011 15.9 0.0 0.03 14.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EXF78766.1 - 0.021 14.8 0.0 0.052 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain RuvB_N PF05496.7 EXF78766.1 - 0.022 13.8 0.0 0.046 12.7 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_23 PF13476.1 EXF78766.1 - 0.051 13.9 8.2 1.2 9.4 5.7 2.5 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EXF78766.1 - 0.058 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EXF78766.1 - 0.058 13.4 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_22 PF13401.1 EXF78766.1 - 0.063 13.4 0.0 0.15 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EXF78766.1 - 0.071 12.5 0.0 0.46 9.8 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.1 EXF78766.1 - 0.1 12.9 0.4 0.25 11.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain End3 PF12761.2 EXF78766.1 - 0.11 12.1 1.0 0.22 11.1 0.7 1.5 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 NIF PF03031.13 EXF78767.1 - 2.8e-51 173.3 0.6 4.1e-51 172.7 0.4 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Sec61_beta PF03911.11 EXF78767.1 - 8.5e-20 70.2 1.5 1.4e-19 69.6 1.0 1.3 1 0 0 1 1 1 1 Sec61beta family Glyco_transf_28 PF03033.15 EXF78768.1 - 3.1e-19 69.0 0.2 5.3e-13 48.9 0.0 2.7 2 0 0 2 2 2 2 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EXF78768.1 - 2.8e-06 26.1 0.0 4.7e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EXF78768.1 - 0.0013 18.4 0.7 0.01 15.5 0.0 2.3 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain ATG_C PF09333.6 EXF78768.1 - 0.0034 17.5 0.0 0.01 15.9 0.0 1.7 1 0 0 1 1 1 1 ATG C terminal domain UIM PF02809.15 EXF78768.1 - 1 9.1 27.4 1.2 8.9 0.1 5.7 6 0 0 6 6 6 0 Ubiquitin interaction motif NARP1 PF12569.3 EXF78769.1 - 4.4 5.9 9.5 6.9 5.3 6.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 PAF-AH_p_II PF03403.8 EXF78770.1 - 2.7e-48 164.1 0.1 4.2e-44 150.3 0.0 3.0 2 1 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EXF78770.1 - 2.6e-14 53.2 0.2 5.1e-13 48.9 0.0 2.4 2 1 0 2 2 2 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EXF78770.1 - 3.8e-07 29.2 0.0 3.8e-05 22.7 0.0 2.2 2 0 0 2 2 2 2 Chlorophyllase enzyme Chlorophyllase PF07224.6 EXF78770.1 - 4.5e-07 28.9 0.0 2.8e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 Chlorophyllase Abhydrolase_6 PF12697.2 EXF78770.1 - 5.5e-07 29.7 0.0 2.4e-06 27.6 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EXF78770.1 - 0.0098 15.7 0.0 0.029 14.1 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase Fungal_trans PF04082.13 EXF78771.1 - 1.4e-14 53.5 0.0 2.2e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FUSC_2 PF13515.1 EXF78771.1 - 0.076 12.9 0.1 0.18 11.7 0.1 1.5 1 0 0 1 1 1 0 Fusaric acid resistance protein-like COesterase PF00135.23 EXF78773.1 - 1.2e-74 251.9 0.2 1.2e-68 232.1 0.0 2.0 1 1 0 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF78773.1 - 4.7e-07 29.5 0.1 4e-06 26.5 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold MFS_1 PF07690.11 EXF78774.1 - 6.9e-24 84.2 26.2 6.9e-24 84.2 18.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 EXF78777.1 - 2.3e-19 69.2 0.2 4.1e-19 68.4 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Carboxyl_trans PF01039.17 EXF78778.1 - 1.9e-101 339.8 0.0 3e-101 339.2 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain ECH PF00378.15 EXF78778.1 - 4.6e-42 143.8 0.4 3.8e-40 137.5 0.0 3.0 3 0 0 3 3 3 1 Enoyl-CoA hydratase/isomerase family HMGL-like PF00682.14 EXF78778.1 - 2.5e-39 135.3 0.0 4.4e-39 134.5 0.0 1.4 1 0 0 1 1 1 1 HMGL-like AMP-binding PF00501.23 EXF78779.1 - 1.1e-90 304.0 0.0 1.4e-90 303.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EXF78779.1 - 1.8e-14 54.4 0.0 5.1e-14 52.9 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CPSase_L_D2 PF02786.12 EXF78780.1 - 4.1e-69 232.0 0.0 6.3e-69 231.4 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EXF78780.1 - 7.4e-37 125.8 0.0 2.1e-36 124.3 0.0 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EXF78780.1 - 4.9e-28 97.2 0.0 9.1e-28 96.3 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EXF78780.1 - 1.1e-15 57.8 0.0 2.1e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.17 EXF78780.1 - 1.7e-12 47.0 0.0 3.8e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EXF78780.1 - 2e-10 40.4 0.0 5.2e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EXF78780.1 - 3.6e-10 39.1 0.0 9.6e-10 37.7 0.0 1.6 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EXF78780.1 - 1.2e-07 31.7 0.0 2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EXF78780.1 - 2.6e-07 30.1 3.1 5.6e-07 29.1 2.2 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme WH1 PF00568.18 EXF78780.1 - 0.062 13.0 0.0 2.1 8.1 0.0 2.8 3 0 0 3 3 3 0 WH1 domain SnoaL_2 PF12680.2 EXF78781.1 - 0.0094 16.3 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain DUF3176 PF11374.3 EXF78782.1 - 1.4e-21 76.4 1.7 3.9e-21 75.0 1.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) adh_short PF00106.20 EXF78782.1 - 7e-14 52.0 1.3 2.8e-13 50.1 0.9 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF78782.1 - 3.4e-07 30.1 0.1 8.1e-07 28.8 0.0 1.6 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EXF78782.1 - 2.7e-05 24.0 0.4 9.6e-05 22.2 0.3 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EXF78782.1 - 2.8e-05 23.6 0.2 0.00024 20.6 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF78782.1 - 0.033 14.2 0.8 0.064 13.2 0.6 1.5 1 1 0 1 1 1 0 NADH(P)-binding NmrA PF05368.8 EXF78782.1 - 0.047 12.9 0.3 0.082 12.1 0.2 1.3 1 0 0 1 1 1 0 NmrA-like family NAD_binding_4 PF07993.7 EXF78782.1 - 0.065 12.1 0.2 1.3 7.8 0.1 2.5 2 1 0 2 2 2 0 Male sterility protein p450 PF00067.17 EXF78783.1 - 8.1e-44 149.9 0.0 2.1e-43 148.5 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_11 PF08241.7 EXF78784.1 - 3.8e-15 56.1 0.0 6.5e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF78784.1 - 2.9e-10 40.1 0.0 4.8e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF78784.1 - 3.2e-10 40.3 0.0 5.2e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF78784.1 - 6.3e-10 39.6 0.0 1.1e-09 38.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF78784.1 - 5.1e-09 35.8 0.0 1e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF78784.1 - 8.6e-09 35.6 0.0 2.1e-08 34.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF78784.1 - 7.2e-07 29.2 0.1 1.7e-06 28.0 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF78784.1 - 0.00034 19.8 0.0 0.0005 19.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EXF78784.1 - 0.019 13.9 0.0 4.1 6.3 0.0 2.3 2 0 0 2 2 2 0 Putative methyltransferase CMAS PF02353.15 EXF78784.1 - 0.02 13.9 0.0 0.072 12.1 0.0 1.8 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase DREV PF05219.7 EXF78784.1 - 0.03 13.2 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase MTS PF05175.9 EXF78784.1 - 0.034 13.5 0.0 0.21 10.9 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase small domain RrnaAD PF00398.15 EXF78784.1 - 0.13 11.3 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase p450 PF00067.17 EXF78786.1 - 3.4e-66 223.6 0.0 1.5e-61 208.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 BTP PF05232.7 EXF78786.1 - 0.035 13.8 0.7 0.084 12.6 0.5 1.6 1 0 0 1 1 1 0 Bacterial Transmembrane Pair family zf-CCHC_5 PF14787.1 EXF78787.1 - 0.22 11.0 2.4 0.29 10.6 0.3 2.2 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Metallophos PF00149.23 EXF78788.1 - 3.2e-13 49.5 2.8 6.5e-12 45.2 1.9 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_3 PF00933.16 EXF78789.1 - 9.4e-83 277.6 0.0 1.4e-82 277.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF78789.1 - 2.5e-72 243.0 0.4 2.8e-70 236.3 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF78789.1 - 1.2e-22 79.6 0.1 2.4e-22 78.6 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EXF78789.1 - 3e-18 65.8 0.0 5.2e-18 65.0 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Asp_protease_2 PF13650.1 EXF78791.1 - 3.7e-12 46.5 0.0 9.1e-06 26.0 0.0 2.4 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.1 EXF78791.1 - 8.3e-10 38.3 0.0 0.00036 20.3 0.0 2.5 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease RVP PF00077.15 EXF78791.1 - 5.3e-05 23.0 0.0 0.48 10.3 0.0 2.5 2 0 0 2 2 2 2 Retroviral aspartyl protease Asp_protease PF09668.5 EXF78791.1 - 0.011 15.2 0.0 5.6 6.5 0.0 2.5 2 1 0 2 2 2 0 Aspartyl protease ANT PF03374.9 EXF78792.1 - 0.044 13.8 0.1 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Phage antirepressor protein KilAC domain Cation_efflux PF01545.16 EXF78793.1 - 1.9e-77 260.1 9.3 8.7e-77 257.9 6.4 1.8 1 1 0 1 1 1 1 Cation efflux family Peptidase_M1 PF01433.15 EXF78794.1 - 9.4e-07 28.2 0.0 0.008 15.3 0.0 3.2 3 0 0 3 3 3 3 Peptidase family M1 SAS4 PF15460.1 EXF78795.1 - 4.8e-35 119.4 0.2 1.6e-34 117.7 0.1 2.0 1 0 0 1 1 1 1 Something about silencing, SAS, complex subunit 4 Adaptin_binding PF10199.4 EXF78795.1 - 0.011 16.0 9.0 0.039 14.2 6.3 2.0 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Nop14 PF04147.7 EXF78795.1 - 0.044 11.7 12.3 0.063 11.1 8.6 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EXF78795.1 - 1.1 7.1 11.2 1.7 6.5 7.8 1.3 1 0 0 1 1 1 0 CDC45-like protein BTV_NS2 PF04514.7 EXF78795.1 - 1.9 7.3 7.6 3.5 6.4 5.3 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 F-box-like PF12937.2 EXF78796.1 - 0.0039 16.8 0.0 0.0069 16.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like PRANC PF09372.5 EXF78796.1 - 0.039 13.9 0.3 0.073 13.0 0.0 1.6 2 0 0 2 2 2 0 PRANC domain CDP-OH_P_transf PF01066.16 EXF78797.1 - 1.2e-15 57.5 5.7 1.2e-15 57.5 3.9 2.4 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase Herpes_capsid PF06112.6 EXF78798.1 - 6 6.8 8.0 8.9 6.3 5.6 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein IQ PF00612.22 EXF78800.1 - 0.00025 20.4 1.5 0.00074 18.9 1.0 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif SSP160 PF06933.6 EXF78800.1 - 0.43 8.5 12.8 0.87 7.4 8.9 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 F-box PF00646.28 EXF78801.1 - 0.00088 18.8 0.2 0.0021 17.6 0.1 1.6 1 0 0 1 1 1 1 F-box domain TPP_enzyme_N PF02776.13 EXF78802.1 - 7.1e-43 146.0 0.2 3.8e-42 143.7 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EXF78802.1 - 1.7e-23 82.8 1.2 1.7e-23 82.8 0.8 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EXF78802.1 - 9.1e-23 80.5 0.0 1.5e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain ABC2_membrane PF01061.19 EXF78803.1 - 2.3e-96 320.9 51.6 2.9e-49 167.0 11.5 2.5 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EXF78803.1 - 1.6e-35 122.3 0.0 4.6e-16 59.3 0.0 3.3 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 EXF78803.1 - 3.7e-35 119.7 2.3 7.4e-32 109.0 0.0 3.1 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 EXF78803.1 - 8.8e-20 70.5 0.1 2.2e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EXF78803.1 - 3.2e-08 33.2 0.0 6.4e-05 22.4 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EXF78803.1 - 5e-07 29.8 3.2 3.7e-06 27.0 0.1 2.7 3 0 0 3 3 2 1 AAA ATPase domain DUF258 PF03193.11 EXF78803.1 - 4.5e-05 22.7 0.0 0.0019 17.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EXF78803.1 - 8.9e-05 21.9 0.1 0.024 14.1 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_33 PF13671.1 EXF78803.1 - 0.0001 22.2 0.1 0.079 12.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 EXF78803.1 - 0.00011 21.3 12.9 0.00011 21.3 8.9 3.2 2 1 0 2 2 2 1 ABC-2 family transporter protein cobW PF02492.14 EXF78803.1 - 0.00018 20.9 0.6 0.0038 16.6 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_22 PF13401.1 EXF78803.1 - 0.0017 18.5 0.2 0.7 10.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EXF78803.1 - 0.0021 17.7 0.1 2.7 7.7 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 EXF78803.1 - 0.0024 18.6 0.0 1.1 10.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EXF78803.1 - 0.0042 16.3 0.0 2.8 7.1 0.0 3.7 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 EXF78803.1 - 0.0049 16.5 0.1 2 8.0 0.1 2.6 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.1 EXF78803.1 - 0.011 15.7 0.0 0.95 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EXF78803.1 - 0.016 14.8 0.2 3 7.4 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DUF2273 PF10031.4 EXF78803.1 - 0.017 14.7 1.0 0.064 12.8 0.7 2.1 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) AAA_18 PF13238.1 EXF78803.1 - 0.017 15.4 0.0 0.91 9.8 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EXF78803.1 - 0.026 14.7 0.0 4.7 7.4 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EXF78803.1 - 0.048 13.2 0.1 0.94 9.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EXF78803.1 - 0.14 12.4 0.0 0.49 10.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EXF78803.1 - 0.15 11.5 1.4 7 5.9 0.1 2.7 2 0 0 2 2 2 0 AAA-like domain Viral_helicase1 PF01443.13 EXF78803.1 - 0.15 11.5 0.0 3 7.3 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.1 EXF78803.1 - 0.16 11.9 0.6 1.6 8.6 0.0 2.5 3 0 0 3 3 2 0 AAA domain Arch_ATPase PF01637.13 EXF78803.1 - 0.16 11.6 0.0 2.4 7.7 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase IstB_IS21 PF01695.12 EXF78803.1 - 0.21 11.0 0.0 16 4.8 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein T2SE PF00437.15 EXF78803.1 - 0.49 9.2 0.4 2.8 6.7 0.0 2.0 2 0 0 2 2 2 0 Type II/IV secretion system protein NPP1 PF05630.6 EXF78804.1 - 1e-28 100.4 0.2 1.1e-22 80.7 0.1 2.4 2 1 0 2 2 2 2 Necrosis inducing protein (NPP1) adh_short PF00106.20 EXF78808.1 - 2.9e-21 76.1 2.1 5.4e-21 75.2 1.5 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF78808.1 - 1.7e-14 54.1 0.0 2.2e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EXF78808.1 - 3.3e-11 43.5 0.6 1.5e-10 41.3 0.2 2.1 1 1 1 2 2 2 1 NADH(P)-binding KR PF08659.5 EXF78808.1 - 6.2e-08 32.5 1.9 7e-08 32.3 0.4 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EXF78808.1 - 4.3e-06 26.3 0.4 8.6e-06 25.3 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 EXF78808.1 - 0.0015 18.0 0.4 0.0047 16.4 0.2 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase F420_oxidored PF03807.12 EXF78808.1 - 0.0033 17.8 0.6 0.083 13.3 0.1 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NmrA PF05368.8 EXF78808.1 - 0.0081 15.4 0.2 0.018 14.3 0.1 1.6 1 1 0 1 1 1 1 NmrA-like family DUF1776 PF08643.5 EXF78808.1 - 0.016 14.3 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DFP PF04127.10 EXF78808.1 - 0.017 14.7 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein Eno-Rase_NADH_b PF12242.3 EXF78808.1 - 0.021 14.6 0.1 0.071 12.9 0.1 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 EXF78808.1 - 0.054 12.3 0.2 0.094 11.5 0.2 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_2 PF03446.10 EXF78808.1 - 0.08 12.7 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Peptidase_M28 PF04389.12 EXF78809.1 - 3.3e-39 134.4 0.0 4.3e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M28 Ribophorin_II PF05817.9 EXF78810.1 - 1e-24 86.7 0.0 1.3e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Glyco_hydro_76 PF03663.9 EXF78812.1 - 7.1e-21 75.0 4.0 1.4e-19 70.6 0.5 3.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 76 Cep57_CLD_2 PF14197.1 EXF78813.1 - 6.7e-30 102.8 58.4 5.3e-16 58.3 4.7 5.6 4 1 1 5 5 5 2 Centrosome localisation domain of PPC89 Cep57_MT_bd PF06657.8 EXF78813.1 - 6.7e-24 83.6 0.4 6.7e-24 83.6 0.3 6.5 7 0 0 7 7 7 2 Centrosome microtubule-binding domain of Cep57 ATG16 PF08614.6 EXF78813.1 - 3.4e-05 23.7 32.0 3.4e-05 23.7 22.2 6.3 4 2 2 6 6 6 2 Autophagy protein 16 (ATG16) Tropomyosin_1 PF12718.2 EXF78813.1 - 0.0028 17.5 2.1 0.0028 17.5 1.4 7.3 4 1 4 8 8 8 1 Tropomyosin like DUF730 PF05325.6 EXF78813.1 - 0.99 9.2 10.3 0.055 13.2 0.5 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF730) NAD_binding_10 PF13460.1 EXF78814.1 - 8.6e-07 29.1 0.0 1.5e-06 28.3 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EXF78814.1 - 1.8e-06 27.3 0.0 2.7e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Glyco_transf_4 PF13439.1 EXF78814.1 - 0.087 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Fungal_trans_2 PF11951.3 EXF78815.1 - 1.4e-23 83.1 6.0 1.7e-11 43.3 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF78815.1 - 1.1e-09 37.9 5.6 2.2e-09 37.0 3.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.2 EXF78816.1 - 1.2e-102 336.3 5.2 9.9e-19 67.4 0.0 6.2 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EXF78816.1 - 1.7e-76 248.4 9.8 6.1e-07 28.9 0.1 13.5 13 0 0 13 13 13 12 Ankyrin repeat Ank_3 PF13606.1 EXF78816.1 - 1.9e-61 197.8 4.4 9.4e-05 22.3 0.0 12.7 12 0 0 12 12 12 11 Ankyrin repeat Ank_5 PF13857.1 EXF78816.1 - 1.4e-56 187.2 10.3 1.1e-07 31.9 0.0 10.9 2 2 9 11 11 11 11 Ankyrin repeats (many copies) Ank_4 PF13637.1 EXF78816.1 - 1e-54 181.9 1.2 2e-08 34.5 0.0 9.7 3 3 8 11 11 11 10 Ankyrin repeats (many copies) An_peroxidase PF03098.10 EXF78817.1 - 2.9e-117 392.2 0.0 3.2e-117 392.1 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase RhoGAP PF00620.22 EXF78818.1 - 7.8e-48 161.9 0.0 1.7e-47 160.8 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EXF78818.1 - 2.6e-12 46.7 1.1 2.6e-12 46.7 0.7 1.9 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF4407 PF14362.1 EXF78818.1 - 0.015 14.2 5.7 0.027 13.4 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.7 EXF78818.1 - 1.9 8.2 12.7 9 6.0 4.6 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein CMS1 PF14617.1 EXF78819.1 - 1.4e-88 296.2 0.6 1.7e-88 295.9 0.4 1.0 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.24 EXF78819.1 - 1.6e-07 30.9 0.0 1.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase RRM_1 PF00076.17 EXF78820.1 - 1.4e-09 37.4 0.0 4.4e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF78820.1 - 1e-07 31.8 0.0 2.3e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF78820.1 - 0.017 14.9 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ras PF00071.17 EXF78821.1 - 4.3e-54 182.2 0.0 4.9e-54 182.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EXF78821.1 - 7.6e-18 65.1 0.0 1.1e-17 64.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EXF78821.1 - 6.7e-07 28.7 0.0 8.8e-07 28.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Epimerase PF01370.16 EXF78822.1 - 3.2e-13 49.6 0.0 5.3e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF78822.1 - 2.1e-12 47.4 0.0 1.7e-11 44.4 0.0 2.3 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EXF78822.1 - 8e-08 31.3 0.0 2e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EXF78822.1 - 9.1e-05 21.5 0.2 0.00044 19.2 0.1 1.9 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EXF78822.1 - 0.032 14.1 1.8 0.05 13.5 0.2 2.1 2 1 0 2 2 2 0 short chain dehydrogenase NmrA PF05368.8 EXF78822.1 - 0.14 11.4 0.0 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family CENP-T PF15511.1 EXF78823.1 - 1.1e-96 324.6 23.2 1.1e-96 324.6 16.1 1.7 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T CENP-S PF15630.1 EXF78823.1 - 1.5e-08 34.6 0.1 2.7e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S Histone PF00125.19 EXF78823.1 - 4.5e-06 26.6 0.0 1.5e-05 25.0 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EXF78823.1 - 0.00024 21.1 0.0 0.00043 20.2 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SURF1 PF02104.10 EXF78824.1 - 3.9e-67 226.1 0.1 5e-67 225.8 0.1 1.1 1 0 0 1 1 1 1 SURF1 family UBX PF00789.15 EXF78825.1 - 2e-09 37.3 0.0 3.5e-09 36.6 0.0 1.4 1 0 0 1 1 1 1 UBX domain PAT1 PF09770.4 EXF78825.1 - 0.78 7.9 9.4 1 7.4 6.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Borrelia_P83 PF05262.6 EXF78825.1 - 6.6 4.8 16.9 9.4 4.3 11.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Hid1 PF12722.2 EXF78825.1 - 7.4 4.1 5.4 9.2 3.7 3.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CHCH PF06747.8 EXF78826.1 - 0.00085 19.1 4.8 0.0013 18.5 3.3 1.3 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.4 EXF78826.1 - 0.0043 17.1 0.5 0.0043 17.1 0.4 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) GCK PF07802.6 EXF78826.1 - 0.062 13.4 0.3 0.16 12.1 0.1 1.7 1 1 1 2 2 2 0 GCK domain Sas10_Utp3 PF04000.10 EXF78827.1 - 4.2e-18 65.3 0.5 4.2e-18 65.3 0.4 1.8 2 0 0 2 2 2 1 Sas10/Utp3/C1D family COG2 PF06148.6 EXF78827.1 - 0.26 11.1 3.8 7.4 6.4 0.0 2.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CHAD PF05235.9 EXF78827.1 - 0.4 10.2 5.6 0.85 9.1 3.9 1.8 1 1 0 1 1 1 0 CHAD domain ApbA_C PF08546.6 EXF78828.1 - 5.7e-18 65.1 0.0 1.4e-17 63.8 0.0 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EXF78828.1 - 1.4e-06 27.8 0.0 2.8e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA dsDNA_bind PF01984.15 EXF78829.1 - 2e-35 121.0 13.1 2.5e-35 120.7 9.1 1.1 1 0 0 1 1 1 1 Double-stranded DNA-binding domain SUZ PF12752.2 EXF78829.1 - 0.015 15.8 1.6 0.034 14.6 1.1 1.6 1 0 0 1 1 1 0 SUZ domain Fes1 PF08609.5 EXF78829.1 - 0.14 12.6 1.0 0.22 12.0 0.4 1.6 1 1 0 1 1 1 0 Nucleotide exchange factor Fes1 Gly-zipper_OmpA PF13436.1 EXF78829.1 - 0.15 11.6 4.0 0.28 10.8 2.8 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Prok-TraM PF09228.5 EXF78829.1 - 0.85 9.8 4.2 1.1 9.3 1.3 2.1 1 1 1 2 2 2 0 Prokaryotic Transcriptional repressor TraM Alb1 PF09135.6 EXF78829.1 - 2.1 8.9 8.0 9.8 6.8 0.2 2.4 1 1 1 2 2 2 0 Alb1 Coq4 PF05019.8 EXF78830.1 - 9.2e-95 315.7 0.0 1.1e-94 315.5 0.0 1.0 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 SET PF00856.23 EXF78831.1 - 3.6e-12 46.8 0.0 6.8e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 SET domain DUF1338 PF07063.8 EXF78831.1 - 0.019 14.0 0.1 0.038 13.0 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1338) RRM_6 PF14259.1 EXF78832.1 - 5e-05 23.2 0.0 8.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EXF78832.1 - 0.00021 20.8 0.0 0.00038 20.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF78832.1 - 0.015 15.1 0.5 0.03 14.1 0.0 1.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Borrelia_P83 PF05262.6 EXF78832.1 - 0.5 8.5 5.3 0.63 8.2 3.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein CDC45 PF02724.9 EXF78832.1 - 9.3 4.1 7.6 10 4.0 5.2 1.1 1 0 0 1 1 1 0 CDC45-like protein SecE PF00584.15 EXF78833.1 - 9.3e-13 47.5 0.0 1e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex WD40 PF00400.27 EXF78834.1 - 7.5e-27 92.2 11.9 1.1e-08 34.6 0.3 6.7 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EXF78834.1 - 0.00067 18.0 3.2 0.35 9.1 0.0 4.0 3 1 1 4 4 4 2 Cytochrome D1 heme domain PD40 PF07676.7 EXF78834.1 - 0.029 14.0 0.2 0.18 11.5 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat SDA1 PF05285.7 EXF78834.1 - 0.1 11.8 6.0 0.15 11.2 4.1 1.2 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 EXF78834.1 - 2.6 6.4 11.8 3.7 5.9 8.1 1.1 1 0 0 1 1 1 0 Daxx Family UPF0016 PF01169.14 EXF78835.1 - 2.5e-42 142.8 24.8 1.6e-22 79.4 5.1 2.2 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 UPF0370 PF13980.1 EXF78835.1 - 0.14 12.0 0.1 0.43 10.4 0.1 1.9 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) HET PF06985.6 EXF78836.1 - 3.1e-21 75.9 0.0 7.7e-21 74.7 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_S8 PF00082.17 EXF78838.1 - 1.5e-27 96.4 0.0 2.4e-27 95.7 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Ank_2 PF12796.2 EXF78839.1 - 2.5e-14 53.3 0.0 5.3e-06 26.6 0.0 3.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) NACHT PF05729.7 EXF78839.1 - 1.7e-13 50.5 0.0 3.4e-13 49.6 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Ank PF00023.25 EXF78839.1 - 8.2e-08 31.6 6.7 0.074 12.9 0.0 6.4 4 3 1 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EXF78839.1 - 1.4e-07 31.8 0.1 0.0018 18.7 0.0 4.6 2 2 2 4 4 4 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF78839.1 - 4.4e-05 23.5 0.1 0.0037 17.4 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) AAA_16 PF13191.1 EXF78839.1 - 6.5e-05 22.9 0.9 0.00031 20.7 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain PNP_UDP_1 PF01048.15 EXF78839.1 - 0.00023 20.2 0.0 0.0012 17.8 0.0 2.2 2 1 0 2 2 2 1 Phosphorylase superfamily Ank_3 PF13606.1 EXF78839.1 - 0.00074 19.5 0.1 0.2 12.0 0.0 4.5 4 1 0 4 4 3 1 Ankyrin repeat NB-ARC PF00931.17 EXF78839.1 - 0.019 13.8 0.0 0.037 12.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EXF78839.1 - 0.061 13.5 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 RNA helicase UPF0079 PF02367.12 EXF78839.1 - 0.065 12.8 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 EXF78839.1 - 0.087 12.9 0.0 0.23 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Cys_Met_Meta_PP PF01053.15 EXF78841.1 - 7.9e-138 458.9 0.0 9.2e-138 458.7 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EXF78841.1 - 3.2e-07 29.6 0.0 7.3e-07 28.4 0.0 1.5 2 0 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EXF78841.1 - 1.9e-06 26.8 0.0 4.8e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 EXF78841.1 - 6.1e-05 21.5 0.4 0.00021 19.7 0.2 1.7 1 1 0 1 1 1 1 Methionine gamma-lyase DegT_DnrJ_EryC1 PF01041.12 EXF78841.1 - 0.00028 20.0 0.1 0.0006 18.9 0.0 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EXF78841.1 - 0.0064 15.6 0.0 0.023 13.8 0.0 1.8 1 1 0 1 1 1 1 Beta-eliminating lyase PELOTA_1 PF15608.1 EXF78841.1 - 0.017 14.9 1.2 0.066 12.9 0.8 1.9 1 1 1 2 2 2 0 PELOTA RNA binding domain Serinc PF03348.10 EXF78842.1 - 1.4e-165 551.1 3.1 1.9e-165 550.7 2.1 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) MFS_1 PF07690.11 EXF78843.1 - 2.2e-18 66.1 34.6 2.7e-16 59.2 7.3 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 EXF78843.1 - 8.1e-15 54.7 3.4 8.1e-15 54.7 2.4 1.9 2 0 0 2 2 2 1 Nodulin-like DUF1673 PF07895.6 EXF78843.1 - 0.12 11.8 5.3 9.1 5.7 0.0 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1673) PGAP1 PF07819.8 EXF78844.1 - 4.1e-88 294.7 0.0 6.1e-88 294.1 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EXF78844.1 - 1.7e-05 24.6 0.0 3.3e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF78844.1 - 0.00081 19.3 0.1 0.0019 18.1 0.1 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF78844.1 - 0.0096 15.4 0.0 0.024 14.1 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF676 PF05057.9 EXF78844.1 - 0.064 12.5 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) COesterase PF00135.23 EXF78844.1 - 0.13 10.9 0.0 0.19 10.4 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family UPF0060 PF02694.10 EXF78844.1 - 0.29 11.1 0.0 0.29 11.1 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised BCR, YnfA/UPF0060 family MutL_C PF08676.6 EXF78845.1 - 6.5e-21 74.4 0.0 1.4e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 EXF78845.1 - 5.9e-20 70.8 0.0 1.4e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EXF78845.1 - 1.3e-13 50.7 0.1 4.7e-13 48.9 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EXF78845.1 - 7.4e-12 44.9 0.0 1.8e-11 43.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pyr_redox_2 PF07992.9 EXF78847.1 - 1.8e-07 31.2 0.0 2.1e-06 27.7 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF78847.1 - 3.4e-06 27.2 0.0 0.00031 20.8 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase ETF PF01012.16 EXF78848.1 - 8.1e-40 136.2 0.6 1.5e-39 135.3 0.1 1.7 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.14 EXF78848.1 - 2.9e-36 122.9 0.3 9.2e-36 121.3 0.2 1.9 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain Involucrin PF00904.12 EXF78848.1 - 9.5 7.1 5.9 0.52 10.9 0.4 1.8 2 0 0 2 2 2 0 Involucrin repeat SWIRM PF04433.12 EXF78849.1 - 2.9e-34 117.0 0.1 5.3e-34 116.2 0.1 1.4 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.26 EXF78849.1 - 8.3e-08 32.1 0.0 1.9e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EXF78849.1 - 2.9e-06 27.2 0.1 7.9e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.12 EXF78849.1 - 0.00023 20.6 3.6 0.00046 19.6 2.5 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Carn_acyltransf PF00755.15 EXF78850.1 - 6.5e-173 576.0 0.0 7.4e-173 575.8 0.0 1.0 1 0 0 1 1 1 1 Choline/Carnitine o-acyltransferase CAP_N PF01213.14 EXF78851.1 - 3.2e-68 230.3 6.5 9.5e-68 228.7 4.5 1.7 1 1 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EXF78851.1 - 1.1e-54 184.1 4.5 1.4e-54 183.7 3.1 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EXF78851.1 - 0.1 12.0 2.0 0.23 10.8 1.0 1.6 1 1 0 1 1 1 0 Tubulin binding cofactor C NDT80_PhoG PF05224.7 EXF78852.1 - 3.3e-34 118.5 0.0 2.1e-33 115.9 0.0 2.0 2 0 0 2 2 2 1 NDT80 / PhoG like DNA-binding family DUF2011 PF09428.5 EXF78853.1 - 3.5e-22 78.6 9.2 6.9e-22 77.7 6.4 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2011) GTP_EFTU PF00009.22 EXF78854.1 - 5.6e-60 202.0 0.2 7.6e-60 201.5 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EXF78854.1 - 1.8e-26 92.2 0.1 5.6e-26 90.6 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EXF78854.1 - 2.2e-16 59.7 2.2 2.2e-16 59.7 1.5 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EXF78854.1 - 6.3e-06 26.1 0.0 1.2e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EXF78854.1 - 0.00056 20.3 0.0 0.0017 18.8 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EXF78854.1 - 0.092 11.8 0.1 0.28 10.2 0.0 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EXF78854.1 - 0.092 12.2 0.2 9.3 5.7 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ribosomal_S14 PF00253.16 EXF78855.1 - 6.5e-19 67.0 4.9 7.1e-19 66.9 3.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF4428 PF14471.1 EXF78855.1 - 0.09 12.5 1.1 0.11 12.2 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4428) ZZ PF00569.12 EXF78855.1 - 0.18 11.3 4.1 2 8.0 2.8 2.1 1 1 0 1 1 1 0 Zinc finger, ZZ type Prim_Zn_Ribbon PF08273.7 EXF78855.1 - 0.28 11.2 1.7 1.9 8.6 0.1 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase Thioredoxin PF00085.15 EXF78856.1 - 4.6e-60 199.7 0.0 1.3e-30 105.1 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EXF78856.1 - 1.3e-26 93.0 0.6 6.3e-26 90.8 0.4 2.1 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EXF78856.1 - 4.7e-16 58.9 0.8 4.2e-07 30.1 0.0 3.6 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EXF78856.1 - 8.5e-13 48.1 0.0 5.5e-06 26.3 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_8 PF13905.1 EXF78856.1 - 2.1e-10 40.5 0.0 3.3e-05 23.9 0.0 3.3 2 1 1 3 3 3 2 Thioredoxin-like AhpC-TSA PF00578.16 EXF78856.1 - 3.8e-07 29.8 0.0 0.004 16.8 0.0 2.4 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.5 EXF78856.1 - 8.5e-06 25.3 0.1 0.0047 16.4 0.0 2.4 2 0 0 2 2 2 2 Redoxin Thioredoxin_9 PF14595.1 EXF78856.1 - 0.00022 20.7 0.0 0.34 10.4 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_4 PF13462.1 EXF78856.1 - 0.0003 20.8 0.8 1.1 9.2 0.0 4.0 3 2 2 5 5 5 1 Thioredoxin ERp29_N PF07912.8 EXF78856.1 - 0.0012 18.8 0.6 0.0036 17.2 0.0 2.1 3 0 0 3 3 3 1 ERp29, N-terminal domain Thioredoxin_3 PF13192.1 EXF78856.1 - 0.0012 18.5 0.0 0.26 11.1 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin domain HyaE PF07449.6 EXF78856.1 - 0.012 15.4 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Glutaredoxin PF00462.19 EXF78856.1 - 0.046 13.7 0.0 9.8 6.2 0.0 2.8 2 0 0 2 2 2 0 Glutaredoxin HSBP1 PF06825.7 EXF78857.1 - 1.4e-15 56.5 0.1 1.7e-15 56.3 0.1 1.1 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Baculo_PEP_C PF04513.7 EXF78857.1 - 0.01 15.6 0.1 0.012 15.4 0.1 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus SF-assemblin PF06705.6 EXF78857.1 - 0.026 13.6 0.2 0.03 13.4 0.1 1.0 1 0 0 1 1 1 0 SF-assemblin/beta giardin DUF2884 PF11101.3 EXF78857.1 - 0.056 12.8 0.1 0.057 12.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) CheX PF13690.1 EXF78857.1 - 0.058 13.2 0.1 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 Chemotaxis phosphatase CheX DUF1664 PF07889.7 EXF78857.1 - 0.065 13.0 0.1 0.078 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Matrilin_ccoil PF10393.4 EXF78857.1 - 0.076 12.3 0.1 0.99 8.8 0.1 2.1 1 1 1 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin Thiol_cytolysin PF01289.14 EXF78857.1 - 0.077 11.3 0.1 0.085 11.2 0.0 1.0 1 0 0 1 1 1 0 Thiol-activated cytolysin TipAS PF07739.8 EXF78857.1 - 0.09 13.1 0.0 0.16 12.3 0.0 1.4 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain zf-rbx1 PF12678.2 EXF78858.1 - 3.2e-09 36.7 0.2 6e-09 35.8 0.2 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EXF78858.1 - 3.1e-08 33.2 7.7 1.7e-07 30.9 5.4 2.1 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EXF78858.1 - 5.7e-07 29.0 0.5 9.4e-07 28.3 0.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EXF78858.1 - 1.5e-06 27.8 2.3 3.6e-06 26.6 1.6 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EXF78858.1 - 1.5e-05 24.5 4.8 8.3e-05 22.1 3.4 2.0 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EXF78858.1 - 0.00017 21.5 2.4 0.00017 21.5 1.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EXF78858.1 - 0.015 15.1 0.9 0.039 13.8 0.6 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF2921 PF11145.3 EXF78858.1 - 0.026 12.2 0.8 0.037 11.7 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) FixQ PF05545.6 EXF78858.1 - 0.19 11.4 3.2 0.25 10.9 0.2 2.6 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ zf-RING_UBOX PF13445.1 EXF78858.1 - 0.23 11.2 5.7 0.068 12.9 0.6 2.4 2 1 0 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 EXF78858.1 - 8.5 6.4 6.0 2.1 8.3 1.5 1.9 2 1 0 2 2 2 0 FANCL C-terminal domain Glyco_hydro_61 PF03443.9 EXF78860.1 - 3.4e-53 180.6 0.8 4e-53 180.4 0.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 EXF78860.1 - 0.017 15.1 0.2 0.49 10.4 0.0 2.6 2 1 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase SprB PF13573.1 EXF78860.1 - 1 9.0 7.1 10 5.8 0.1 3.6 3 0 0 3 3 3 0 SprB repeat Zn_clus PF00172.13 EXF78861.1 - 6.7e-07 29.1 7.9 1.5e-06 27.9 5.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF1256 PF06866.6 EXF78862.1 - 0.077 12.1 0.3 5.3 6.2 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1256) DUF2890 PF11081.3 EXF78862.1 - 0.083 12.9 0.9 0.14 12.2 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Sporozoite_P67 PF05642.6 EXF78862.1 - 0.088 10.6 1.0 0.11 10.3 0.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FtsA PF14450.1 EXF78862.1 - 0.14 11.9 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Cell division protein FtsA DUF605 PF04652.11 EXF78862.1 - 1.4 8.2 7.1 1.7 7.9 4.9 1.1 1 0 0 1 1 1 0 Vta1 like Nucleoplasmin PF03066.10 EXF78862.1 - 4.6 6.7 8.0 7.5 6.0 5.5 1.3 1 0 0 1 1 1 0 Nucleoplasmin Pkinase PF00069.20 EXF78863.1 - 4.3e-45 153.8 0.0 1.6e-44 152.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF78863.1 - 1.6e-31 109.3 0.0 2.3e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF78863.1 - 0.0025 16.8 0.0 0.0043 16.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EXF78863.1 - 0.015 14.4 0.0 0.076 12.0 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family adh_short PF00106.20 EXF78864.1 - 8.6e-23 81.0 0.9 1e-22 80.8 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF78864.1 - 8.3e-15 55.2 0.0 1.2e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF78864.1 - 2.4e-07 30.5 0.1 3.5e-07 30.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Ldh_1_N PF00056.18 EXF78864.1 - 0.0096 15.7 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain PD-C2-AF1 PF09310.5 EXF78864.1 - 0.087 11.9 0.0 0.14 11.3 0.0 1.3 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 HHH_5 PF14520.1 EXF78864.1 - 0.11 12.6 0.1 0.23 11.6 0.1 1.7 1 1 0 1 1 1 0 Helix-hairpin-helix domain Fungal_trans PF04082.13 EXF78865.1 - 2e-21 76.0 0.0 3.5e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain CTP_transf_2 PF01467.21 EXF78866.1 - 0.0004 20.4 0.9 0.0026 17.8 0.6 2.3 1 1 0 1 1 1 1 Cytidylyltransferase F-box-like PF12937.2 EXF78867.1 - 2.4e-05 23.9 0.2 2.4e-05 23.9 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EXF78867.1 - 5.8e-05 22.6 0.3 0.00019 20.9 0.1 2.0 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.1 EXF78867.1 - 0.16 12.1 0.7 4.6 7.6 0.3 3.0 3 0 0 3 3 3 0 Leucine Rich repeat Acyl-CoA_dh_1 PF00441.19 EXF78869.1 - 8.1e-25 87.6 0.6 1.3e-24 87.0 0.4 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EXF78869.1 - 2.6e-12 47.3 0.8 8.5e-12 45.6 0.0 2.2 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EXF78869.1 - 2.9e-08 34.0 0.0 6.1e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EXF78869.1 - 1.1e-05 24.8 0.0 2.1e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Aldedh PF00171.17 EXF78870.1 - 2.5e-159 530.5 0.0 2.9e-159 530.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EXF78870.1 - 0.016 13.9 0.0 0.038 12.7 0.0 1.5 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EXF78870.1 - 0.079 12.1 0.0 6.7 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) adh_short PF00106.20 EXF78871.1 - 1.1e-22 80.7 0.4 1.5e-22 80.3 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF78871.1 - 2.8e-22 79.6 0.0 3.6e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF78871.1 - 2e-07 30.8 0.2 3.1e-07 30.2 0.1 1.3 1 0 0 1 1 1 1 KR domain AMP-binding PF00501.23 EXF78872.1 - 2.4e-91 306.2 0.0 3e-91 305.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EXF78872.1 - 3e-10 40.8 0.6 9e-10 39.3 0.4 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pyr_redox_3 PF13738.1 EXF78873.1 - 1.6e-20 74.0 0.0 1.2e-19 71.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EXF78873.1 - 1.4e-13 49.8 0.0 3.8e-10 38.5 0.0 2.9 2 2 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EXF78873.1 - 1.2e-09 38.0 0.0 3.6e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EXF78873.1 - 0.00014 21.6 0.1 0.00098 18.9 0.0 2.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EXF78873.1 - 0.0008 18.4 0.0 0.42 9.4 0.0 3.0 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) SOBP PF15279.1 EXF78874.1 - 3.1 8.0 24.9 4.1 7.6 17.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein PAT1 PF09770.4 EXF78874.1 - 6 4.9 18.3 7.1 4.7 12.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ExoD PF06055.7 EXF78875.1 - 0.04 13.0 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD LysM PF01476.15 EXF78876.1 - 8.3e-11 41.6 0.0 1.3e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 LysM domain Sensor PF13796.1 EXF78876.1 - 0.0021 17.7 0.2 0.0029 17.2 0.1 1.1 1 0 0 1 1 1 1 Putative sensor Actino_peptide PF14408.1 EXF78876.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes Neurokinin_B PF03823.9 EXF78876.1 - 0.34 10.7 0.2 0.34 10.7 0.1 2.1 2 0 0 2 2 2 0 Neurokinin B Cellulase PF00150.13 EXF78877.1 - 6.4e-21 74.7 2.6 9.5e-21 74.2 1.8 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EXF78877.1 - 2e-12 46.5 14.7 8.3e-12 44.5 10.2 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain Glyco_hydro_2_C PF02836.12 EXF78877.1 - 0.00018 20.5 0.0 0.00036 19.5 0.0 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 EXF78877.1 - 0.0005 19.3 0.2 0.0011 18.1 0.1 1.5 2 0 0 2 2 2 1 Beta-galactosidase Cellulase-like PF12876.2 EXF78877.1 - 0.0037 17.6 0.0 0.0091 16.4 0.0 1.7 1 1 0 1 1 1 1 Sugar-binding cellulase-like adh_short PF00106.20 EXF78878.1 - 3.5e-23 82.3 0.8 5e-23 81.8 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF78878.1 - 3.1e-09 36.7 0.1 6e-09 35.8 0.0 1.5 2 0 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EXF78878.1 - 2.7e-08 33.0 0.0 4.2e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EXF78878.1 - 4.6e-05 22.9 0.0 6.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.8 EXF78878.1 - 0.0019 17.6 0.0 0.0084 15.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase WecB/TagA/CpsF family Eno-Rase_NADH_b PF12242.3 EXF78878.1 - 0.044 13.5 0.4 0.093 12.5 0.3 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Glyco_hydro_43 PF04616.9 EXF78879.1 - 1.2e-53 182.0 1.4 1.8e-53 181.5 1.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 GFA PF04828.9 EXF78880.1 - 4e-22 77.9 0.2 5.2e-22 77.5 0.1 1.2 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Fungal_trans_2 PF11951.3 EXF78881.1 - 8e-06 24.7 0.0 0.00031 19.4 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF78881.1 - 0.003 17.4 9.3 0.0065 16.3 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EXF78882.1 - 3.1e-27 95.5 4.1 4.1e-27 95.1 2.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF78882.1 - 2e-24 86.6 0.0 2.8e-24 86.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF78882.1 - 1.2e-15 57.6 1.6 1.7e-15 57.1 1.1 1.2 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EXF78882.1 - 0.079 11.6 0.1 0.11 11.2 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family AA_permease_2 PF13520.1 EXF78884.1 - 7.8e-42 143.2 50.5 9.7e-42 142.9 35.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF78884.1 - 9.7e-22 76.9 43.0 1.6e-21 76.2 29.8 1.3 1 0 0 1 1 1 1 Amino acid permease FixH PF05751.6 EXF78884.1 - 5.6 6.7 6.2 27 4.5 0.1 2.9 2 0 0 2 2 2 0 FixH PQQ_2 PF13360.1 EXF78885.1 - 0.00045 19.7 0.2 0.0011 18.5 0.1 1.6 1 1 0 1 1 1 1 PQQ-like domain HET PF06985.6 EXF78886.1 - 1.4e-20 73.8 0.0 2.5e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF2007 PF09413.5 EXF78889.1 - 0.092 12.5 0.0 0.19 11.5 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2007) NGP1NT PF08153.7 EXF78891.1 - 4.7e-47 159.1 0.0 7.8e-47 158.4 0.0 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EXF78891.1 - 2.6e-19 69.2 0.0 4.5e-15 55.6 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EXF78891.1 - 7.5e-06 25.3 0.1 4.2e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EXF78891.1 - 0.00027 20.1 0.0 0.00075 18.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EXF78891.1 - 0.00084 18.8 0.0 0.26 10.7 0.0 3.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EXF78891.1 - 0.00088 18.5 0.0 0.15 11.3 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family Dynamin_N PF00350.18 EXF78891.1 - 0.038 13.7 0.1 3.8 7.2 0.0 3.1 2 1 1 3 3 3 0 Dynamin family DDE_Tnp_IS66_C PF13817.1 EXF78891.1 - 0.13 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 IS66 C-terminal element ABC2_membrane PF01061.19 EXF78893.1 - 4.6e-37 127.2 20.1 9.4e-37 126.2 13.9 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EXF78893.1 - 7.4e-25 87.8 0.0 1.7e-24 86.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EXF78893.1 - 1.6e-09 38.1 0.0 5.5e-09 36.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EXF78893.1 - 8.4e-09 34.9 25.0 8.4e-09 34.9 17.3 1.9 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_25 PF13481.1 EXF78893.1 - 0.00013 21.4 0.0 0.0068 15.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain hEGF PF12661.2 EXF78893.1 - 0.00017 21.4 20.6 0.018 15.0 1.9 4.4 3 0 0 3 3 3 2 Human growth factor-like EGF AAA_29 PF13555.1 EXF78893.1 - 0.0023 17.4 0.0 0.0055 16.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EXF78893.1 - 0.0061 15.7 0.0 0.013 14.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_18 PF13238.1 EXF78893.1 - 0.016 15.4 0.0 0.033 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.1 EXF78893.1 - 0.034 13.1 0.0 1.3 8.0 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain SMC_N PF02463.14 EXF78893.1 - 0.038 13.2 0.0 0.33 10.1 0.0 2.2 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain NACHT PF05729.7 EXF78893.1 - 0.048 13.3 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 EXF78893.1 - 0.05 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EXF78893.1 - 0.057 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.1 EXF78893.1 - 0.085 13.1 0.1 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EXF78893.1 - 0.1 13.4 0.0 0.22 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.2 EXF78893.1 - 0.13 11.0 18.2 6.6 5.4 12.6 2.3 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_33 PF13671.1 EXF78893.1 - 0.19 11.5 0.0 0.34 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EXF78893.1 - 0.19 11.6 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.16 EXF78894.1 - 1.3e-35 123.0 0.0 2.3e-35 122.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EXF78894.1 - 1e-06 27.6 0.0 1.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase Cys_Met_Meta_PP PF01053.15 EXF78894.1 - 0.00012 20.5 0.0 0.00019 19.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EXF78894.1 - 0.00038 19.3 0.0 0.00058 18.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.12 EXF78894.1 - 0.0029 16.7 0.0 0.0043 16.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family CR6_interact PF10147.4 EXF78895.1 - 0.00059 19.2 1.7 0.0011 18.3 1.2 1.6 1 0 0 1 1 1 1 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 Baculo_E56 PF04639.7 EXF78895.1 - 0.028 13.0 0.1 0.056 12.1 0.0 1.5 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope Flu_M2 PF00599.12 EXF78895.1 - 0.046 13.5 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Influenza Matrix protein (M2) Herpes_gE PF02480.11 EXF78895.1 - 0.061 11.5 0.0 0.12 10.6 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E EphA2_TM PF14575.1 EXF78895.1 - 0.12 12.8 0.0 0.31 11.4 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.3 EXF78895.1 - 5.5 7.5 9.3 1.6 9.3 2.2 2.8 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red CDK2AP PF09806.4 EXF78896.1 - 1.6 8.8 11.2 0.023 14.9 1.8 1.9 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein Ribosomal_S8 PF00410.14 EXF78897.1 - 3.4e-23 81.8 0.0 4.7e-23 81.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 Iso_dh PF00180.15 EXF78899.1 - 4.1e-98 328.5 0.0 7.6e-98 327.6 0.0 1.4 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase CHASE3 PF05227.8 EXF78899.1 - 0.12 12.0 0.4 0.27 10.9 0.3 1.6 1 1 0 1 1 1 0 CHASE3 domain SET PF00856.23 EXF78900.1 - 3.4e-06 27.4 0.0 7.2e-06 26.3 0.0 1.6 1 1 0 1 1 1 1 SET domain MFS_1 PF07690.11 EXF78902.1 - 8.5e-23 80.6 29.0 8.5e-23 80.6 20.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EXF78902.1 - 0.64 8.0 5.0 4.7 5.1 2.6 2.9 2 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Tir_receptor_C PF07489.6 EXF78902.1 - 1.5 8.5 5.1 3.6 7.2 0.0 2.8 3 0 0 3 3 3 0 Translocated intimin receptor (Tir) C-terminus DUF3040 PF11239.3 EXF78902.1 - 2.4 8.2 6.8 2.5 8.1 1.8 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) zf-DHHC PF01529.15 EXF78903.1 - 0.82 9.0 4.7 0.43 9.9 0.1 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase Methyltransf_22 PF13383.1 EXF78904.1 - 5.9e-25 88.2 0.0 7.8e-25 87.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 EXF78904.1 - 2.1e-06 27.7 0.0 3.1e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Flavodoxin_1 PF00258.20 EXF78905.1 - 1.5e-09 38.0 0.0 2.2e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin FMN_red PF03358.10 EXF78905.1 - 3.8e-07 29.7 0.0 5.6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EXF78905.1 - 5.4e-05 22.7 0.0 7.3e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Flavodoxin_5 PF12724.2 EXF78905.1 - 0.005 16.8 0.0 0.18 11.7 0.0 2.2 1 1 1 2 2 2 1 Flavodoxin domain Flavodoxin_4 PF12682.2 EXF78905.1 - 0.081 12.2 0.1 0.63 9.3 0.1 2.1 1 1 0 1 1 1 0 Flavodoxin Sulfotransfer_3 PF13469.1 EXF78906.1 - 6.6e-08 33.6 5.4 1.4e-07 32.5 3.7 1.5 1 1 0 1 1 1 1 Sulfotransferase family MFS_1 PF07690.11 EXF78907.1 - 4.3e-26 91.4 58.3 4.8e-24 84.7 29.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3328 PF11807.3 EXF78908.1 - 3.1e-25 89.1 0.0 4.1e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) GTP_EFTU PF00009.22 EXF78909.1 - 7.3e-57 191.8 0.4 1.4e-56 190.9 0.3 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_II PF14492.1 EXF78909.1 - 1.8e-32 111.0 0.0 3.7e-32 110.0 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_IV PF03764.13 EXF78909.1 - 1.4e-28 98.8 0.0 2.9e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EXF78909.1 - 9.2e-22 76.7 0.0 2.1e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EXF78909.1 - 1.1e-13 51.0 0.0 2.8e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 DUF442 PF04273.8 EXF78909.1 - 0.018 14.9 0.1 0.99 9.2 0.0 3.2 3 0 0 3 3 3 0 Putative phosphatase (DUF442) DUF2762 PF10960.3 EXF78910.1 - 0.72 9.5 3.6 2.3 8.0 2.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2762) MIP-T3 PF10243.4 EXF78910.1 - 5.7 5.2 36.8 2.3 6.5 23.3 1.9 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Exo_endo_phos PF03372.18 EXF78912.1 - 6.5e-11 42.6 0.2 8.4e-11 42.2 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EXF78912.1 - 0.019 14.5 0.0 0.15 11.6 0.0 2.4 2 1 0 2 2 2 0 Endonuclease-reverse transcriptase Mito_carr PF00153.22 EXF78915.1 - 1.9e-58 194.1 7.9 1e-23 82.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.13 EXF78916.1 - 6.4e-24 84.2 0.3 1.3e-23 83.2 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF805 PF05656.9 EXF78918.1 - 0.0066 16.2 3.6 0.011 15.5 2.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF805) PgaD PF13994.1 EXF78918.1 - 2.9 7.3 5.3 0.55 9.7 0.3 2.1 1 1 1 2 2 2 0 PgaD-like protein Glyco_hydro_12 PF01670.11 EXF78919.1 - 2.1e-34 118.5 0.1 3.6e-34 117.7 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 Ank_2 PF12796.2 EXF78920.1 - 1.1e-67 224.3 11.7 1.6e-17 63.6 0.3 10.8 9 2 2 12 12 12 9 Ankyrin repeats (3 copies) Ank PF00023.25 EXF78920.1 - 1.7e-51 169.5 12.0 2.9e-06 26.8 0.0 16.0 16 1 0 16 16 16 8 Ankyrin repeat Ank_4 PF13637.1 EXF78920.1 - 3e-38 129.5 18.9 1.7e-08 34.7 0.1 12.9 12 4 4 16 16 16 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF78920.1 - 5.4e-33 109.7 19.5 0.0018 18.3 0.0 16.6 18 0 0 18 18 18 6 Ankyrin repeat Ank_5 PF13857.1 EXF78920.1 - 1.5e-29 101.3 22.1 1.1e-08 35.0 0.0 13.9 12 4 5 17 17 17 5 Ankyrin repeats (many copies) Transferase PF02458.10 EXF78920.1 - 1.4e-11 43.5 0.0 4.4e-11 41.8 0.0 1.7 1 1 0 1 1 1 1 Transferase family Shigella_OspC PF06128.6 EXF78920.1 - 0.39 10.1 0.1 31 3.9 0.0 3.5 3 1 1 4 4 4 0 Shigella flexneri OspC protein Mito_carr PF00153.22 EXF78921.1 - 6.8e-59 195.5 4.6 9.1e-20 70.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Phage_Coat_B PF05356.6 EXF78921.1 - 0.048 13.3 1.5 2 8.1 0.0 3.1 3 1 0 3 3 3 0 Phage Coat protein B FA_hydroxylase PF04116.8 EXF78922.1 - 1.1e-06 28.9 13.0 2.2e-06 28.0 9.0 1.5 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily p450 PF00067.17 EXF78923.1 - 1.2e-61 208.6 0.0 1.6e-61 208.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 2OG-FeII_Oxy PF03171.15 EXF78924.1 - 1.4e-16 60.5 0.0 2e-16 60.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EXF78924.1 - 8e-13 48.9 0.0 1.3e-12 48.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Transp_cyt_pur PF02133.10 EXF78925.1 - 1.5e-92 310.4 29.3 1.7e-92 310.2 20.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Asp_Glu_race PF01177.17 EXF78926.1 - 2e-26 93.2 0.1 2.5e-26 92.9 0.1 1.1 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase Fungal_trans PF04082.13 EXF78927.1 - 6.7e-06 25.1 0.4 1.1e-05 24.4 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF78927.1 - 0.00014 21.7 6.4 0.00041 20.1 4.4 1.8 1 1 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pyr_redox_2 PF07992.9 EXF78928.1 - 2.5e-29 102.6 0.3 3.1e-29 102.3 0.2 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF78928.1 - 6.1e-18 65.0 2.0 3.1e-16 59.5 0.3 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF78928.1 - 4.1e-12 46.5 0.1 3.7e-08 33.6 0.0 3.1 2 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF78928.1 - 1.6e-07 30.6 2.3 0.23 10.3 0.1 3.3 3 0 0 3 3 3 3 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EXF78928.1 - 8.1e-07 29.2 0.1 0.00022 21.4 0.0 2.6 2 1 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.12 EXF78928.1 - 2.5e-05 23.5 0.2 0.00071 18.7 0.0 2.4 2 0 0 2 2 2 1 Thi4 family K_oxygenase PF13434.1 EXF78928.1 - 6.4e-05 22.0 0.1 0.0061 15.5 0.0 3.0 2 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EXF78928.1 - 0.00014 21.8 1.0 0.026 14.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EXF78928.1 - 0.00023 21.2 1.1 0.21 11.7 0.1 2.8 2 1 1 3 3 3 2 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EXF78928.1 - 0.00044 19.2 5.3 0.4 9.4 0.3 3.9 3 1 1 4 4 4 1 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EXF78928.1 - 0.0055 15.6 6.9 0.17 10.6 0.2 3.4 3 1 0 4 4 4 2 FAD binding domain Trp_halogenase PF04820.9 EXF78928.1 - 0.02 13.5 0.2 0.39 9.2 0.0 2.3 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EXF78928.1 - 0.029 14.1 0.1 3.1 7.5 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_oxidored PF12831.2 EXF78928.1 - 0.032 13.3 0.1 0.062 12.3 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EXF78928.1 - 0.068 12.2 1.4 4.5 6.2 0.0 2.9 2 1 1 3 3 3 0 FAD binding domain HI0933_like PF03486.9 EXF78928.1 - 0.082 11.3 1.0 2.4 6.5 0.1 2.9 2 1 0 3 3 3 0 HI0933-like protein DUF3357 PF11837.3 EXF78929.1 - 0.006 16.4 0.5 0.014 15.2 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3357) PAN_1 PF00024.21 EXF78929.1 - 0.12 12.1 0.1 0.36 10.6 0.0 1.8 1 1 0 1 1 1 0 PAN domain SOG2 PF10428.4 EXF78929.1 - 0.14 10.7 2.6 0.17 10.4 1.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Mid2 PF04478.7 EXF78930.1 - 0.026 13.9 0.1 0.043 13.2 0.1 1.3 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor SKG6 PF08693.5 EXF78930.1 - 0.06 12.6 2.0 0.072 12.4 0.1 2.1 2 0 0 2 2 2 0 Transmembrane alpha-helix domain ELO PF01151.13 EXF78931.1 - 5.5e-63 212.5 15.0 7.2e-63 212.2 10.4 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family Senescence PF06911.7 EXF78932.1 - 0.0094 15.6 2.8 0.013 15.2 1.9 1.2 1 0 0 1 1 1 1 Senescence-associated protein tRNA-synt_2 PF00152.15 EXF78933.1 - 8.4e-100 333.7 0.0 1.4e-99 333.0 0.0 1.4 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EXF78933.1 - 0.00032 20.3 0.1 0.0027 17.3 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) ANTH PF07651.11 EXF78934.1 - 3e-67 226.2 0.1 3.8e-67 225.9 0.1 1.1 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EXF78934.1 - 9.5e-07 28.7 0.0 1.6e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 ENTH domain MAT1 PF06391.8 EXF78935.1 - 1.5e-31 109.5 3.1 1.9e-31 109.2 2.2 1.1 1 0 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 zf-C3HC4 PF00097.20 EXF78935.1 - 0.00053 19.5 2.8 0.0012 18.4 1.9 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EXF78935.1 - 0.021 14.8 5.9 0.049 13.6 4.1 1.6 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Plug PF07715.10 EXF78935.1 - 0.022 15.0 0.0 0.037 14.3 0.0 1.4 1 0 0 1 1 1 0 TonB-dependent Receptor Plug Domain zf-C3HC4_3 PF13920.1 EXF78935.1 - 0.031 13.9 5.9 0.053 13.2 4.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EXF78935.1 - 0.18 11.6 6.5 0.57 10.0 4.5 1.8 1 1 1 2 2 2 0 Ring finger domain zf-RING_5 PF14634.1 EXF78935.1 - 0.31 10.8 9.1 2.9 7.6 6.7 2.1 1 1 1 2 2 2 0 zinc-RING finger domain zf-UDP PF14569.1 EXF78935.1 - 0.68 9.7 4.2 1.9 8.3 2.9 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.1 EXF78935.1 - 1.6 8.3 10.4 19 4.9 7.7 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain CS PF04969.11 EXF78936.1 - 1.1e-16 61.1 0.1 1.9e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 CS domain Prefoldin_3 PF13758.1 EXF78937.1 - 1.3e-32 111.4 1.6 1.3e-32 111.4 1.1 2.1 2 0 0 2 2 2 1 Prefoldin subunit DUF3835 PF12927.2 EXF78937.1 - 5.1e-15 56.1 0.1 5.1e-15 56.1 0.1 5.2 5 1 0 5 5 5 1 Domain of unknown function (DUF3835) Prefoldin_2 PF01920.15 EXF78937.1 - 0.0015 18.2 6.1 0.59 9.9 0.1 3.7 3 0 0 3 3 3 2 Prefoldin subunit DHC_N1 PF08385.7 EXF78937.1 - 0.062 11.6 0.2 0.12 10.7 0.1 1.4 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 Lzipper-MIP1 PF14389.1 EXF78937.1 - 0.2 11.8 5.6 1.3 9.2 0.6 3.5 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Prefoldin PF02996.12 EXF78937.1 - 0.38 10.3 5.2 9.4 5.9 0.0 3.0 3 0 0 3 3 3 0 Prefoldin subunit V_ATPase_I PF01496.14 EXF78937.1 - 2.1 6.1 6.0 0.16 9.8 1.0 1.4 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family TMF_TATA_bd PF12325.3 EXF78937.1 - 3.1 7.5 11.7 3.8 7.2 0.4 3.4 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding p450 PF00067.17 EXF78938.1 - 3.6e-65 220.2 0.0 4.2e-65 220.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_31 PF01055.21 EXF78939.1 - 1.2e-156 521.9 5.0 1.5e-156 521.6 3.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 DUF4094 PF13334.1 EXF78939.1 - 0.012 15.9 0.1 0.045 14.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) zf-CCCH PF00642.19 EXF78940.1 - 3.5e-21 74.3 32.0 5.6e-08 32.2 0.4 5.5 4 1 1 5 5 5 5 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EXF78940.1 - 0.0081 16.1 34.8 0.037 14.0 0.4 5.9 5 1 0 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type Methyltransf_23 PF13489.1 EXF78941.1 - 2.7e-13 49.9 0.0 8.5e-13 48.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF78941.1 - 0.0013 19.1 0.0 0.0031 17.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF78941.1 - 0.004 16.7 0.1 0.11 12.0 0.0 2.3 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF78941.1 - 0.01 16.2 0.0 0.03 14.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EXF78941.1 - 0.018 15.6 0.2 0.23 12.0 0.0 2.5 2 1 1 3 3 3 0 Methyltransferase domain Glyco_hydro_18 PF00704.23 EXF78942.1 - 1.1e-72 245.4 0.0 1.2e-72 245.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Vps53_N PF04100.7 EXF78943.1 - 4.2e-104 348.3 0.1 6.9e-104 347.6 0.1 1.3 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 EXF78943.1 - 8.5e-08 31.4 3.6 1.8e-07 30.3 2.5 1.4 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) Spc7 PF08317.6 EXF78943.1 - 0.015 13.9 3.5 0.017 13.8 1.6 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein Zw10 PF06248.8 EXF78943.1 - 0.02 13.0 6.7 0.0066 14.6 1.3 2.2 3 0 0 3 3 3 0 Centromere/kinetochore Zw10 Uds1 PF15456.1 EXF78943.1 - 0.16 12.0 7.6 0.44 10.5 0.4 2.5 1 1 1 2 2 2 0 Up-regulated During Septation DUF1776 PF08643.5 EXF78944.1 - 9.5e-109 363.1 0.0 1.2e-108 362.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) MFS_1 PF07690.11 EXF78945.1 - 4.4e-19 68.4 55.4 6.8e-12 44.7 18.8 3.3 2 1 0 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF78945.1 - 2.1e-08 32.8 19.7 3.2e-08 32.2 13.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF2214 PF09980.4 EXF78945.1 - 0.015 15.0 0.0 0.015 15.0 0.0 2.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2214) DUF4225 PF13988.1 EXF78945.1 - 0.083 12.3 3.4 0.038 13.4 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4225) zf-CHY PF05495.7 EXF78946.1 - 1.2e-16 60.6 25.2 2.5e-15 56.3 9.9 3.3 3 0 0 3 3 3 2 CHY zinc finger RWD PF05773.17 EXF78946.1 - 7e-05 22.6 0.3 0.039 13.8 0.0 2.5 2 0 0 2 2 2 2 RWD domain Mu-like_Com PF10122.4 EXF78946.1 - 0.00012 21.0 4.3 0.00012 20.9 0.7 2.8 2 0 0 2 2 2 1 Mu-like prophage protein Com Myotoxins PF00819.12 EXF78947.1 - 0.063 13.3 1.1 0.14 12.2 0.8 1.5 1 0 0 1 1 1 0 Myotoxin Fungal_trans PF04082.13 EXF78948.1 - 1.7e-26 92.6 0.0 2.6e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF78948.1 - 3.5e-06 26.8 13.6 5.7e-06 26.1 9.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gal4_dimer PF03902.8 EXF78948.1 - 0.002 18.0 1.2 0.0036 17.1 0.9 1.4 1 0 0 1 1 1 1 Gal4-like dimerisation domain Sugar_tr PF00083.19 EXF78949.1 - 1.3e-85 287.7 23.6 1.5e-85 287.4 16.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF78949.1 - 4e-31 108.0 32.0 1.1e-28 99.9 15.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EXF78949.1 - 2e-05 23.2 29.4 3.2e-05 22.5 1.3 2.8 2 1 1 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.2 EXF78949.1 - 0.0017 18.1 1.6 1.1 9.1 0.1 3.0 2 0 0 2 2 2 2 MFS_1 like family TRI12 PF06609.8 EXF78949.1 - 0.0033 15.6 0.4 0.0033 15.6 0.3 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) adh_short PF00106.20 EXF78950.1 - 9.1e-28 97.2 2.5 1.1e-27 96.9 1.7 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF78950.1 - 2.2e-23 83.2 0.1 3.7e-23 82.5 0.1 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF78950.1 - 4.9e-13 49.1 0.8 7e-13 48.6 0.6 1.3 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF78950.1 - 0.00017 21.1 0.0 0.00025 20.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EXF78950.1 - 0.0018 17.3 0.2 0.0025 16.8 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EXF78950.1 - 0.0032 16.2 0.0 0.0043 15.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family 2-Hacid_dh_C PF02826.14 EXF78950.1 - 0.0035 16.4 0.3 0.0068 15.5 0.2 1.4 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EXF78950.1 - 0.0054 17.1 0.8 0.012 16.0 0.6 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EXF78950.1 - 0.03 13.9 0.6 0.043 13.4 0.4 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EXF78950.1 - 0.031 13.1 0.0 0.039 12.8 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EXF78950.1 - 0.053 12.4 0.7 0.11 11.4 0.1 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain NAD_Gly3P_dh_N PF01210.18 EXF78950.1 - 0.059 13.1 0.2 0.096 12.4 0.2 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_10 PF13460.1 EXF78950.1 - 0.11 12.5 1.3 0.18 11.7 0.9 1.4 1 1 0 1 1 1 0 NADH(P)-binding AAA_19 PF13245.1 EXF78951.1 - 1.9e-06 27.5 0.4 8.4e-06 25.4 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain PRK PF00485.13 EXF78951.1 - 3.4e-06 26.7 0.0 4.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EXF78951.1 - 3.7e-06 27.7 0.0 8.3e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EXF78951.1 - 3.7e-06 27.0 0.1 7.9e-06 25.9 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 EXF78951.1 - 1.1e-05 24.5 0.2 7.2e-05 21.9 0.0 2.2 2 1 0 2 2 2 1 Zeta toxin NACHT PF05729.7 EXF78951.1 - 3.3e-05 23.6 0.0 0.00094 18.8 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.1 EXF78951.1 - 0.00016 22.0 0.0 0.00048 20.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EXF78951.1 - 0.00044 20.4 0.0 0.00083 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EXF78951.1 - 0.00076 19.3 0.0 0.004 17.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EXF78951.1 - 0.00094 18.9 0.1 0.0027 17.4 0.0 1.7 2 0 0 2 2 2 1 NTPase AAA PF00004.24 EXF78951.1 - 0.001 19.2 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EXF78951.1 - 0.0029 17.3 0.0 0.0064 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 EXF78951.1 - 0.0046 15.8 0.0 0.0069 15.2 0.0 1.2 1 0 0 1 1 1 1 NB-ARC domain T2SE PF00437.15 EXF78951.1 - 0.005 15.7 0.0 0.007 15.3 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 EXF78951.1 - 0.0098 15.4 0.0 0.015 14.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain SRP54 PF00448.17 EXF78951.1 - 0.018 14.4 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.1 EXF78951.1 - 0.02 14.2 0.0 0.042 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EXF78951.1 - 0.025 14.7 0.0 0.043 13.9 0.0 1.4 1 0 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.16 EXF78951.1 - 0.028 13.6 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EXF78951.1 - 0.03 14.2 0.0 0.23 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.5 EXF78951.1 - 0.069 12.3 0.0 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 MobB PF03205.9 EXF78951.1 - 0.073 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EXF78951.1 - 0.081 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 EXF78951.1 - 0.082 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EXF78951.1 - 0.086 12.8 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.7 EXF78951.1 - 0.092 11.7 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus FtsK_SpoIIIE PF01580.13 EXF78951.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_11 PF13086.1 EXF78951.1 - 0.11 12.0 0.0 0.11 12.0 0.0 1.3 1 1 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EXF78951.1 - 0.14 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.1 EXF78951.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.1 EXF78951.1 - 0.16 11.5 0.0 0.31 10.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 EXF78951.1 - 0.17 10.8 0.0 0.18 10.7 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain ADH_N PF08240.7 EXF78952.1 - 9e-32 109.0 0.4 9e-32 109.0 0.3 2.3 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF78952.1 - 5.6e-26 90.6 0.6 1.1e-25 89.6 0.4 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF78952.1 - 1.3e-05 26.0 0.1 3.4e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CMAS PF02353.15 EXF78952.1 - 0.00018 20.6 0.1 0.00028 20.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EXF78952.1 - 0.0003 21.3 0.1 0.00066 20.2 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF78952.1 - 0.0024 17.4 0.1 0.0047 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain 2-Hacid_dh_C PF02826.14 EXF78952.1 - 0.0059 15.7 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_11 PF08241.7 EXF78952.1 - 0.0093 16.4 0.0 0.019 15.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF78952.1 - 0.029 14.3 0.1 0.048 13.6 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EXF78952.1 - 0.037 13.7 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EXF78952.1 - 0.052 12.6 0.1 0.083 11.9 0.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 EXF78952.1 - 0.11 12.8 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EXF78952.1 - 0.13 12.7 0.0 0.27 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 EXF78953.1 - 3.8e-32 111.5 3.7 4.9e-32 111.1 2.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF78953.1 - 1.2e-24 87.4 0.1 1.5e-24 87.1 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF78953.1 - 8.4e-15 54.8 1.6 1.3e-14 54.2 1.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF78953.1 - 0.0042 16.5 1.0 0.009 15.4 0.7 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EXF78953.1 - 0.017 14.0 2.7 0.34 9.7 0.0 2.2 1 1 1 2 2 2 0 RmlD substrate binding domain AIRC PF00731.15 EXF78953.1 - 0.018 14.2 0.4 2.6 7.3 0.1 2.4 2 0 0 2 2 2 0 AIR carboxylase SET PF00856.23 EXF78954.1 - 6.6e-10 39.5 0.0 1.2e-08 35.4 0.0 2.2 1 1 0 1 1 1 1 SET domain TPR_8 PF13181.1 EXF78954.1 - 0.058 13.2 0.2 0.73 9.7 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Sugar_tr PF00083.19 EXF78957.1 - 5.8e-80 269.0 22.1 7.4e-80 268.7 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF78957.1 - 9.4e-18 64.0 50.1 1.1e-16 60.4 14.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CFEM PF05730.6 EXF78958.1 - 3.3e-12 46.0 4.0 7.3e-12 44.9 2.8 1.6 1 0 0 1 1 1 1 CFEM domain PBP PF01161.15 EXF78960.1 - 4.7e-19 68.6 0.0 5.6e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein FANCI_S2 PF14676.1 EXF78960.1 - 0.082 12.8 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 FANCI solenoid 2 HhH-GPD PF00730.20 EXF78961.1 - 2.2e-20 72.9 0.0 5.4e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 EXF78961.1 - 1.4e-17 63.0 0.0 3.5e-17 61.8 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain HHH PF00633.18 EXF78961.1 - 0.00084 18.9 0.1 0.0024 17.4 0.1 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EXF78961.1 - 0.041 14.0 0.1 0.57 10.3 0.0 2.7 2 0 0 2 2 2 0 Helix-hairpin-helix domain FeS PF04060.8 EXF78961.1 - 4.9 6.8 6.9 0.66 9.5 1.1 2.3 2 0 0 2 2 2 0 Putative Fe-S cluster Pyr_redox_3 PF13738.1 EXF78962.1 - 7e-24 85.0 0.1 2e-23 83.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EXF78962.1 - 1.6e-10 39.8 0.1 4e-09 35.2 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EXF78962.1 - 7.4e-09 34.9 0.1 1e-06 27.9 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EXF78962.1 - 1.4e-07 31.4 0.2 4e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF78962.1 - 3e-06 27.2 0.0 4.3e-05 23.4 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF78962.1 - 0.00018 20.5 0.0 0.00027 19.9 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_9 PF13454.1 EXF78962.1 - 0.003 17.3 3.4 0.036 13.8 0.0 3.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EXF78962.1 - 0.0036 16.2 0.0 0.14 11.0 0.0 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EXF78962.1 - 0.0048 16.0 0.1 0.028 13.5 0.0 2.1 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.14 EXF78962.1 - 0.012 14.7 0.1 0.025 13.7 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pectate_lyase PF03211.8 EXF78963.1 - 2e-66 223.5 7.8 2.5e-66 223.1 5.4 1.0 1 0 0 1 1 1 1 Pectate lyase Hydantoinase_B PF02538.9 EXF78964.1 - 7.8e-192 638.1 0.0 1e-191 637.8 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EXF78964.1 - 3.5e-92 308.5 0.0 5.5e-91 304.6 0.0 2.2 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EXF78964.1 - 2.2e-57 193.4 2.9 2e-55 187.0 0.0 3.4 4 0 0 4 4 4 2 Hydantoinase/oxoprolinase N-terminal region MFS_1 PF07690.11 EXF78965.1 - 5.3e-14 51.7 0.3 6.1e-14 51.5 0.2 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EXF78965.1 - 0.13 11.7 0.4 0.17 11.3 0.3 1.2 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EXF78966.1 - 1.1e-17 63.7 8.9 1.8e-17 63.1 6.2 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily PNK3P PF08645.6 EXF78967.1 - 5.2e-56 188.4 0.0 7.8e-56 187.9 0.0 1.3 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EXF78967.1 - 1e-30 106.4 0.0 3.7e-30 104.6 0.0 1.9 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EXF78967.1 - 0.00026 20.1 0.0 0.0044 16.1 0.0 2.5 2 1 1 3 3 3 1 Zeta toxin AAA_22 PF13401.1 EXF78967.1 - 0.023 14.8 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EXF78967.1 - 0.047 12.3 0.0 0.073 11.7 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein HAD_2 PF13419.1 EXF78967.1 - 0.055 13.6 0.1 14 5.8 0.0 3.3 3 1 1 4 4 4 0 Haloacid dehalogenase-like hydrolase Med18 PF09637.5 EXF78968.1 - 7.2e-30 104.3 0.0 8.9e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Med18 protein Glyco_hydro_61 PF03443.9 EXF78969.1 - 8.4e-64 215.3 0.5 1.2e-63 214.8 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_16 PF00722.16 EXF78970.1 - 3.3e-09 36.2 0.4 3.5e-08 32.9 0.2 2.1 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 EXF78970.1 - 1e-05 23.9 0.0 0.0072 14.5 0.1 2.2 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) DUF3433 PF11915.3 EXF78971.1 - 1e-10 41.6 16.5 1.1e-09 38.2 1.5 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) UPRTase PF14681.1 EXF78974.1 - 9.8e-19 67.3 0.0 3.5e-09 36.1 0.0 2.3 1 1 1 2 2 2 2 Uracil phosphoribosyltransferase HAD PF12710.2 EXF78974.1 - 9e-12 45.5 0.1 6.7e-11 42.7 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EXF78974.1 - 1.8e-08 35.0 0.0 2.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase AAA_17 PF13207.1 EXF78974.1 - 4.6e-05 24.2 0.0 0.00016 22.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain HAD_2 PF13419.1 EXF78974.1 - 0.00017 21.8 0.2 0.00063 20.0 0.0 2.0 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Zeta_toxin PF06414.7 EXF78974.1 - 0.045 12.8 0.0 0.096 11.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 EXF78974.1 - 0.046 13.6 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Torsin PF06309.6 EXF78974.1 - 0.11 12.4 0.1 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 Torsin Hydrolase_3 PF08282.7 EXF78974.1 - 0.16 11.5 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase MFS_1 PF07690.11 EXF78975.1 - 5.2e-46 156.9 45.8 1.6e-45 155.3 31.7 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EXF78975.1 - 2.8e-10 39.0 22.7 3.6e-10 38.6 15.8 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) WTF PF03303.8 EXF78975.1 - 0.95 8.8 4.2 19 4.5 0.0 2.5 2 0 0 2 2 2 0 WTF protein Fungal_trans PF04082.13 EXF78976.1 - 1.3e-23 83.2 0.0 2.1e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF78976.1 - 3.4e-09 36.4 9.2 5.5e-09 35.7 6.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MSP1_C PF07462.6 EXF78976.1 - 0.083 11.2 0.8 0.14 10.4 0.6 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Aconitase PF00330.15 EXF78977.1 - 1.2e-69 235.0 0.5 4.5e-42 144.1 0.0 2.2 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EXF78977.1 - 5.8e-23 81.4 0.0 1.1e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain IPPT PF01715.12 EXF78978.1 - 1.4e-52 178.2 0.1 3.7e-52 176.8 0.1 1.7 1 1 0 1 1 1 1 IPP transferase AAA_17 PF13207.1 EXF78978.1 - 4.4e-06 27.4 0.1 1.3e-05 25.9 0.1 2.1 1 1 0 1 1 1 1 AAA domain IPT PF01745.11 EXF78978.1 - 5.3e-05 22.4 0.0 0.00014 21.0 0.0 1.6 1 0 0 1 1 1 1 Isopentenyl transferase AAA_33 PF13671.1 EXF78978.1 - 0.00023 21.0 0.6 0.019 14.8 0.0 3.0 3 1 0 3 3 3 1 AAA domain zf-met PF12874.2 EXF78978.1 - 0.00027 21.0 1.9 0.00049 20.2 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type AAA_18 PF13238.1 EXF78978.1 - 0.00057 20.1 0.2 0.046 14.0 0.1 2.5 1 1 0 1 1 1 1 AAA domain zf-C2H2_jaz PF12171.3 EXF78978.1 - 0.0011 18.9 1.8 0.002 18.2 1.2 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding AAA_28 PF13521.1 EXF78978.1 - 0.0025 17.7 1.0 0.13 12.2 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EXF78978.1 - 0.0085 15.8 0.0 0.025 14.3 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain Hpr_kinase_C PF07475.7 EXF78978.1 - 0.012 14.9 0.0 0.022 14.0 0.0 1.3 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA_22 PF13401.1 EXF78978.1 - 0.021 14.9 0.1 0.085 13.0 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EXF78978.1 - 0.021 15.1 0.0 0.066 13.5 0.0 1.9 2 0 0 2 2 2 0 ABC transporter zf-C2H2_2 PF12756.2 EXF78978.1 - 0.025 14.6 0.6 0.048 13.7 0.4 1.4 1 0 0 1 1 1 0 C2H2 type zinc-finger (2 copies) Zeta_toxin PF06414.7 EXF78978.1 - 0.041 12.9 0.2 0.27 10.2 0.0 2.3 3 0 0 3 3 3 0 Zeta toxin AAA_5 PF07728.9 EXF78978.1 - 0.059 13.1 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EXF78978.1 - 0.06 13.5 0.0 0.19 11.9 0.0 1.9 2 0 0 2 2 1 0 RNA helicase PhoH PF02562.11 EXF78978.1 - 0.091 11.9 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein SecY PF00344.15 EXF78979.1 - 9.4e-96 320.7 9.8 1.2e-95 320.3 6.8 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EXF78979.1 - 1.4e-17 62.8 0.1 1.1e-16 60.0 0.2 2.4 2 0 0 2 2 2 1 Plug domain of Sec61p ABC_tran PF00005.22 EXF78980.1 - 2.9e-49 166.8 4.0 2.3e-30 105.6 0.0 3.3 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 EXF78980.1 - 5.5e-44 150.6 22.5 1.8e-24 86.6 5.9 3.5 3 0 0 3 3 3 3 ABC transporter transmembrane region AAA_23 PF13476.1 EXF78980.1 - 1.6e-08 35.0 19.5 0.00018 21.9 0.0 3.8 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.1 EXF78980.1 - 9.3e-08 32.3 0.0 0.0091 15.9 0.0 4.2 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EXF78980.1 - 1.8e-05 24.1 0.3 0.14 11.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 EXF78980.1 - 2.7e-05 23.7 0.0 0.031 13.7 0.0 3.3 3 0 0 3 3 3 1 AAA-like domain AAA_25 PF13481.1 EXF78980.1 - 4.6e-05 22.9 0.0 0.41 10.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EXF78980.1 - 5.8e-05 22.1 0.1 0.016 14.1 0.1 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein SMC_N PF02463.14 EXF78980.1 - 6.5e-05 22.2 14.6 0.008 15.4 0.0 4.4 4 1 0 5 5 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EXF78980.1 - 0.0005 20.2 0.1 3.8 7.6 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EXF78980.1 - 0.0016 19.2 4.9 2.2 9.1 0.0 4.2 4 0 0 4 4 4 2 AAA domain DUF258 PF03193.11 EXF78980.1 - 0.002 17.3 0.0 1.1 8.4 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EXF78980.1 - 0.0024 17.3 0.0 0.46 9.8 0.0 2.7 2 0 0 2 2 2 1 IstB-like ATP binding protein MMR_HSR1 PF01926.18 EXF78980.1 - 0.0051 16.7 0.0 0.25 11.2 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.24 EXF78980.1 - 0.018 15.2 0.4 8.3 6.6 0.0 3.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EXF78980.1 - 0.023 14.1 0.0 5.2 6.4 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family DUF87 PF01935.12 EXF78980.1 - 0.023 14.4 0.0 0.023 14.4 0.0 3.7 3 0 0 3 3 2 0 Domain of unknown function DUF87 AAA_19 PF13245.1 EXF78980.1 - 0.068 12.9 0.7 4.6 7.0 0.1 3.1 2 1 0 2 2 2 0 Part of AAA domain AAA_16 PF13191.1 EXF78980.1 - 0.13 12.2 10.2 0.4 10.6 0.0 3.5 3 1 0 3 3 2 0 AAA ATPase domain RNA_helicase PF00910.17 EXF78980.1 - 0.17 12.0 0.1 30 4.8 0.0 2.9 2 0 0 2 2 2 0 RNA helicase CbiA PF01656.18 EXF78980.1 - 2 7.8 8.1 1.5 8.1 0.0 3.2 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Miro PF08477.8 EXF78980.1 - 5.6 7.4 10.0 5.9 7.4 0.0 3.3 3 0 0 3 3 2 0 Miro-like protein TIP120 PF08623.5 EXF78981.1 - 1.7e-64 216.4 0.7 8.8e-62 207.6 0.0 3.9 4 1 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EXF78981.1 - 2.6e-14 53.2 22.0 0.069 13.4 0.0 9.5 9 1 1 10 10 10 5 HEAT repeats HEAT PF02985.17 EXF78981.1 - 1.7e-08 33.8 16.5 0.27 11.3 0.1 10.0 10 1 1 11 11 11 3 HEAT repeat Adaptin_N PF01602.15 EXF78981.1 - 7e-05 21.3 17.8 0.34 9.1 0.0 6.1 3 2 2 5 5 5 5 Adaptin N terminal region HEAT_EZ PF13513.1 EXF78981.1 - 8.8e-05 22.8 20.9 20 5.8 0.0 11.0 11 4 2 13 13 13 0 HEAT-like repeat Cnd1 PF12717.2 EXF78981.1 - 0.00093 19.0 9.4 0.59 9.9 0.1 6.0 6 3 2 8 8 8 2 non-SMC mitotic condensation complex subunit 1 RIX1 PF08167.7 EXF78981.1 - 0.0058 16.3 0.4 2.1 8.0 0.0 4.5 5 1 0 5 5 5 1 rRNA processing/ribosome biogenesis DUF4042 PF13251.1 EXF78981.1 - 0.036 13.5 7.0 0.3 10.5 0.2 5.0 6 0 0 6 6 6 0 Domain of unknown function (DUF4042) CENP-B_dimeris PF09026.5 EXF78981.1 - 1.5 9.0 11.1 3.9 7.7 7.7 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 EXF78981.1 - 9.6 5.7 8.3 22 4.5 5.7 1.6 1 0 0 1 1 1 0 Nucleoplasmin E1-E2_ATPase PF00122.15 EXF78983.1 - 2.6e-21 75.7 0.0 7.2e-21 74.2 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EXF78983.1 - 1.2e-16 61.7 0.0 4.6e-12 46.7 0.0 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EXF78983.1 - 2.2e-14 54.0 0.0 3e-13 50.3 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EXF78983.1 - 2.5e-12 46.5 0.0 7.4e-12 45.0 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EXF78983.1 - 0.0023 17.5 0.0 0.0076 15.8 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EXF78983.1 - 0.008 16.4 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Homeobox PF00046.24 EXF78984.1 - 1.1e-19 69.8 4.4 2.4e-19 68.6 3.0 1.6 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EXF78984.1 - 0.00022 20.8 0.5 0.00065 19.3 0.4 1.8 1 0 0 1 1 1 1 Homeobox KN domain Adaptin_binding PF10199.4 EXF78987.1 - 8.3e-17 61.7 17.6 2.2e-16 60.3 12.2 1.9 1 1 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 DUF3446 PF11928.3 EXF78987.1 - 2.3 8.4 12.7 5.5 7.2 8.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) DEC-1_N PF04625.8 EXF78987.1 - 3.2 6.3 9.4 6.7 5.2 6.5 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Na_H_antiporter PF03553.9 EXF78988.1 - 0.24 10.3 0.0 0.32 9.9 0.0 1.1 1 0 0 1 1 1 0 Na+/H+ antiporter family ADH_zinc_N_2 PF13602.1 EXF78989.1 - 3.1e-18 66.9 0.8 7.4e-18 65.6 0.3 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EXF78989.1 - 1.2e-13 50.6 1.5 3.6e-13 49.2 1.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Eno-Rase_NADH_b PF12242.3 EXF78989.1 - 0.0037 17.0 1.9 0.0074 16.0 1.3 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ALF PF03752.8 EXF78989.1 - 1.2 9.0 6.7 5.2 7.0 1.2 3.2 3 0 0 3 3 3 0 Short repeats of unknown function HlyIII PF03006.15 EXF78990.1 - 4.7e-13 49.0 10.4 6.2e-13 48.6 7.2 1.1 1 0 0 1 1 1 1 Haemolysin-III related RNA_pol_3_Rpc31 PF11705.3 EXF78991.1 - 0.018 14.9 10.4 0.042 13.7 7.2 1.6 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CENP-B_dimeris PF09026.5 EXF78991.1 - 0.072 13.3 9.0 0.16 12.1 6.2 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain COMP PF11598.3 EXF78991.1 - 0.19 11.8 0.1 0.36 10.9 0.1 1.4 1 0 0 1 1 1 0 Cartilage oligomeric matrix protein CDC45 PF02724.9 EXF78991.1 - 0.58 8.1 6.4 0.89 7.5 4.4 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 EXF78991.1 - 7.9 5.6 8.4 13 4.9 5.8 1.2 1 0 0 1 1 1 0 NOA36 protein DUF2240 PF09999.4 EXF78992.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2240) MFS_1 PF07690.11 EXF78993.1 - 3.8e-19 68.6 47.0 2.2e-18 66.0 13.9 2.7 2 1 1 3 3 3 3 Major Facilitator Superfamily Fungal_trans_2 PF11951.3 EXF78995.1 - 3.3e-15 55.5 0.4 5.5e-14 51.5 0.2 2.0 1 1 1 2 2 2 2 Fungal specific transcription factor domain AA_permease PF00324.16 EXF78997.1 - 1.3e-89 300.8 42.1 1.5e-89 300.5 29.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF78997.1 - 2.3e-23 82.4 45.2 2.9e-23 82.1 31.3 1.1 1 0 0 1 1 1 1 Amino acid permease Ras PF00071.17 EXF78999.1 - 1.6e-47 160.9 0.1 1.6e-40 138.1 0.0 2.4 2 1 0 2 2 2 2 Ras family Miro PF08477.8 EXF78999.1 - 2.7e-14 53.6 0.0 2.1e-07 31.4 0.0 3.1 3 0 0 3 3 3 2 Miro-like protein Abhydrolase_4 PF08386.5 EXF78999.1 - 0.042 13.7 0.0 0.088 12.7 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein FeoB_N PF02421.13 EXF78999.1 - 0.084 12.1 0.0 0.54 9.5 0.0 2.1 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_25 PF13481.1 EXF78999.1 - 0.11 11.9 0.0 0.21 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain HAD_2 PF13419.1 EXF79000.1 - 1.9e-19 70.5 0.0 5.6e-19 69.0 0.0 1.7 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EXF79000.1 - 0.017 15.5 0.0 0.03 14.7 0.0 1.3 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF3381 PF11861.3 EXF79000.1 - 0.032 13.7 0.1 0.053 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Hydrolase_like PF13242.1 EXF79000.1 - 0.11 12.1 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 HAD-hyrolase-like Mcp5_PH PF12814.2 EXF79001.1 - 1.9e-48 163.4 0.0 4.5e-48 162.2 0.0 1.7 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology TPR_MLP1_2 PF07926.7 EXF79001.1 - 0.00051 19.7 8.3 0.00051 19.7 5.8 2.4 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 EXF79001.1 - 0.1 12.4 15.3 0.18 11.6 10.6 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PHTB1_C PF14728.1 EXF79001.1 - 0.2 10.3 3.6 0.3 9.8 2.5 1.2 1 0 0 1 1 1 0 PTHB1 C-terminus TMCO5 PF14992.1 EXF79001.1 - 3.2 6.8 10.9 4.9 6.1 7.6 1.2 1 0 0 1 1 1 0 TMCO5 family SlyX PF04102.7 EXF79001.1 - 6.2 7.2 8.1 3.4 8.1 2.8 2.6 1 1 1 2 2 2 0 SlyX ADIP PF11559.3 EXF79001.1 - 8 6.3 23.6 6 6.7 4.7 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding OTU PF02338.14 EXF79002.1 - 3.8e-19 69.4 1.6 2.7e-18 66.7 0.0 2.8 2 2 0 2 2 2 1 OTU-like cysteine protease PAF-AH_p_II PF03403.8 EXF79002.1 - 0.0031 15.8 1.3 0.0031 15.8 0.9 1.5 2 0 0 2 2 2 1 Platelet-activating factor acetylhydrolase, isoform II Peptidase_C65 PF10275.4 EXF79002.1 - 0.014 14.7 0.0 0.7 9.1 0.0 2.4 2 0 0 2 2 2 0 Peptidase C65 Otubain TPMT PF05724.6 EXF79003.1 - 7e-27 94.2 0.0 2.9e-25 89.0 0.0 2.6 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_18 PF12847.2 EXF79003.1 - 1.4e-07 32.0 0.0 2.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF79003.1 - 1.7e-07 30.9 0.0 4.5e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF79003.1 - 1.1e-06 28.4 0.0 1.8e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF79003.1 - 1.8e-06 28.3 0.0 4.3e-05 23.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF79003.1 - 5.2e-06 26.8 0.0 9.3e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF79003.1 - 3e-05 24.0 0.0 4.7e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF79003.1 - 5.8e-05 23.3 0.0 0.00021 21.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EXF79003.1 - 0.00028 20.0 0.0 0.00045 19.4 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB N2227 PF07942.7 EXF79003.1 - 0.0078 15.1 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein PALP PF00291.20 EXF79004.1 - 2.6e-67 227.2 0.0 4.5e-67 226.4 0.0 1.3 1 1 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme HRDC PF00570.18 EXF79004.1 - 0.029 14.0 0.0 1.9 8.2 0.0 2.5 2 0 0 2 2 2 0 HRDC domain Transglut_core PF01841.14 EXF79004.1 - 0.11 12.7 0.0 0.21 11.8 0.0 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily zf-C3HC4_2 PF13923.1 EXF79005.1 - 3.7e-08 33.2 7.4 6.4e-08 32.4 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EXF79005.1 - 5.4e-08 32.3 6.1 9.2e-08 31.6 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EXF79005.1 - 1.7e-07 30.9 5.6 2.8e-07 30.2 3.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EXF79005.1 - 4.6e-07 29.4 4.3 7.9e-07 28.6 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EXF79005.1 - 2.5e-06 27.2 3.2 5.4e-06 26.1 2.3 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EXF79005.1 - 8.6e-06 25.3 5.1 1.5e-05 24.6 3.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EXF79005.1 - 0.0023 17.6 4.5 0.0062 16.2 3.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 EXF79005.1 - 0.11 12.0 5.2 0.29 10.6 3.4 1.8 1 1 0 1 1 1 0 MIZ/SP-RING zinc finger IP_trans PF02121.13 EXF79005.1 - 0.12 11.5 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol transfer protein Secretin_N_2 PF07655.8 EXF79005.1 - 0.18 12.2 2.1 0.46 10.9 1.5 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain TerY-C PF15616.1 EXF79005.1 - 0.45 10.4 3.2 1.9 8.4 2.2 1.9 1 1 0 1 1 1 0 TerY-C metal binding domain PTS_IIA PF02255.11 EXF79006.1 - 0.12 12.2 5.2 1.5 8.7 3.4 2.6 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIA subunit Fungal_trans PF04082.13 EXF79009.1 - 1.9e-15 56.4 0.3 4.1e-15 55.3 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EXF79009.1 - 6.1e-07 29.4 10.5 0.0048 17.1 0.5 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF79009.1 - 3.8e-06 26.8 9.6 0.00093 19.3 2.1 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger CTP_transf_2 PF01467.21 EXF79011.1 - 1.2e-21 77.4 0.0 2.2e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase K_oxygenase PF13434.1 EXF79012.1 - 1.6e-14 53.5 0.0 6.3e-10 38.4 0.0 2.3 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EXF79012.1 - 1e-12 48.5 0.0 4.5e-10 39.9 0.0 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF79012.1 - 1.7e-05 24.6 0.1 0.0097 15.6 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EXF79012.1 - 0.00013 21.9 0.0 0.063 13.1 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EXF79012.1 - 0.00041 19.5 0.0 0.026 13.6 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EXF79012.1 - 0.0026 16.2 0.0 0.29 9.5 0.0 2.3 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.19 EXF79012.1 - 0.004 16.1 7.5 0.059 12.2 0.2 3.4 2 2 1 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EXF79012.1 - 0.015 15.7 0.2 39 4.7 0.0 3.7 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EXF79012.1 - 0.037 14.1 0.0 6.2 6.9 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 2_5_RNA_ligase2 PF13563.1 EXF79012.1 - 0.058 13.1 0.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 2'-5' RNA ligase superfamily Thi4 PF01946.12 EXF79012.1 - 0.093 11.8 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 EXF79012.1 - 0.096 12.7 0.2 0.43 10.6 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain TFIID-31kDa PF02291.10 EXF79012.1 - 0.1 12.3 0.2 3.9 7.2 0.0 2.5 2 1 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Lycopene_cycl PF05834.7 EXF79012.1 - 0.11 11.3 0.0 0.26 10.1 0.0 1.6 1 0 0 1 1 1 0 Lycopene cyclase protein DUF3405 PF11885.3 EXF79013.1 - 1.4e-184 613.9 0.0 1.7e-184 613.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) TcpQ PF10671.4 EXF79013.1 - 0.018 14.8 0.0 0.046 13.6 0.0 1.6 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q Ribosomal_L44 PF00935.14 EXF79014.1 - 1.6e-34 117.7 11.7 2.2e-34 117.2 8.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L44 SNF2_N PF00176.18 EXF79016.1 - 1.2e-20 73.4 0.3 2.6e-19 69.1 0.2 2.2 1 1 0 1 1 1 1 SNF2 family N-terminal domain DNA_methylase PF00145.12 EXF79016.1 - 3.2e-10 39.6 0.6 1.7e-07 30.7 0.0 2.9 3 0 0 3 3 3 2 C-5 cytosine-specific DNA methylase zf-RING_5 PF14634.1 EXF79016.1 - 0.00032 20.3 6.6 0.00032 20.3 4.6 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EXF79016.1 - 0.0061 16.5 5.9 0.0061 16.5 4.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.10 EXF79016.1 - 0.053 13.3 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Ureidogly_hydro PF04115.7 EXF79017.1 - 2e-51 173.6 0.0 2.5e-51 173.3 0.0 1.0 1 0 0 1 1 1 1 Ureidoglycolate hydrolase Abhydrolase_6 PF12697.2 EXF79018.1 - 5.2e-11 42.8 3.3 8.6e-11 42.1 2.3 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIM PF00412.17 EXF79020.1 - 3.1e-21 75.2 17.3 1.5e-11 44.2 2.4 2.6 3 0 0 3 3 3 2 LIM domain DUF3405 PF11885.3 EXF79021.1 - 5.5e-179 595.5 0.7 9.7e-179 594.7 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3405) Auts2 PF15336.1 EXF79021.1 - 5.2 7.0 8.9 1.7 8.6 3.3 2.0 2 0 0 2 2 2 0 Autism susceptibility gene 2 protein Ank_2 PF12796.2 EXF79023.1 - 2.2e-45 152.9 0.0 8.1e-15 54.9 0.0 6.4 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EXF79023.1 - 1.2e-39 132.1 7.1 8.3e-05 22.2 0.0 11.9 12 0 0 12 12 12 8 Ankyrin repeat Ank_4 PF13637.1 EXF79023.1 - 3.8e-31 106.8 0.1 4.3e-08 33.4 0.0 7.1 5 1 3 8 8 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF79023.1 - 4.5e-22 77.5 0.4 0.0091 16.2 0.0 11.3 8 3 4 12 12 12 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF79023.1 - 2.6e-21 73.5 0.9 0.32 11.3 0.0 10.1 11 0 0 11 11 9 5 Ankyrin repeat V-SNARE PF05008.10 EXF79023.1 - 0.0019 18.3 1.2 0.0019 18.3 0.8 2.5 2 1 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus HrcA PF01628.16 EXF79023.1 - 0.017 14.7 3.6 0.032 13.8 2.5 1.4 1 0 0 1 1 1 0 HrcA protein C terminal domain DUF2408 PF10303.4 EXF79023.1 - 0.018 15.1 0.5 0.057 13.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) AIP3 PF03915.8 EXF79023.1 - 0.06 12.2 1.6 0.063 12.1 0.1 1.7 2 0 0 2 2 2 0 Actin interacting protein 3 FlgN PF05130.7 EXF79023.1 - 0.33 11.2 11.9 0.54 10.4 6.7 2.1 2 0 0 2 2 2 0 FlgN protein CorA PF01544.13 EXF79023.1 - 2.3 7.1 5.4 4.8 6.1 3.7 1.5 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Muted PF14942.1 EXF79023.1 - 2.8 7.8 7.9 0.069 13.0 0.4 2.0 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein Cupin_2 PF07883.6 EXF79024.1 - 7.2e-06 25.4 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cu-oxidase_2 PF07731.9 EXF79026.1 - 4.6e-45 152.5 10.5 3.8e-42 143.0 0.2 3.7 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EXF79026.1 - 1e-43 147.8 3.4 1e-43 147.8 2.4 2.9 4 0 0 4 4 4 1 Multicopper oxidase Cu-oxidase PF00394.17 EXF79026.1 - 3.4e-35 121.3 0.0 1.4e-34 119.3 0.0 2.1 2 0 0 2 2 2 1 Multicopper oxidase Fn3-like PF14310.1 EXF79026.1 - 0.092 12.7 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Fibronectin type III-like domain dCMP_cyt_deam_1 PF00383.17 EXF79028.1 - 1.9e-24 85.2 1.2 3.1e-24 84.5 0.8 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region zf-CCHC PF00098.18 EXF79028.1 - 8.2e-05 22.3 3.6 8.2e-05 22.3 2.5 2.1 2 0 0 2 2 2 1 Zinc knuckle AAA_17 PF13207.1 EXF79028.1 - 0.0027 18.5 0.0 0.01 16.6 0.0 2.1 1 1 0 1 1 1 1 AAA domain CoaE PF01121.15 EXF79028.1 - 0.063 12.6 0.0 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Dephospho-CoA kinase ThiF PF00899.16 EXF79029.1 - 2.3e-28 98.7 0.0 3.7e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EXF79029.1 - 0.0032 17.5 0.0 0.052 13.6 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.11 EXF79030.1 - 3.5e-29 101.6 34.0 3.5e-29 101.6 23.6 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF79030.1 - 1e-18 67.1 25.3 3.7e-15 55.4 5.8 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter DUF1115 PF06544.7 EXF79031.1 - 5e-19 68.2 0.0 7.9e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) Spherulin4 PF12138.3 EXF79031.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Spherulation-specific family 4 DnaJ PF00226.26 EXF79032.1 - 3.8e-12 45.7 0.0 6.4e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain NIT PF08376.5 EXF79032.1 - 0.013 14.9 0.1 0.024 14.1 0.1 1.3 1 0 0 1 1 1 0 Nitrate and nitrite sensing BAMBI PF06211.7 EXF79033.1 - 0.052 13.5 0.4 0.08 12.9 0.3 1.3 1 0 0 1 1 1 0 BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain Paramecium_SA PF01508.11 EXF79033.1 - 7.4 6.8 8.8 3.7 7.8 1.7 2.3 2 0 0 2 2 2 0 Paramecium surface antigen domain YscW PF09619.5 EXF79034.1 - 0.054 13.2 0.0 0.084 12.5 0.0 1.3 1 0 0 1 1 1 0 Type III secretion system lipoprotein chaperone (YscW) ELFV_dehydrog PF00208.16 EXF79036.1 - 5e-12 45.9 0.0 9.8e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EXF79036.1 - 7.8e-08 31.9 0.0 2.2e-07 30.5 0.0 1.7 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Glyoxalase_2 PF12681.2 EXF79036.1 - 1.4e-07 32.0 0.0 1.3e-05 25.7 0.0 3.0 3 0 0 3 3 3 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EXF79036.1 - 3.8e-07 30.0 0.0 3.4e-06 27.0 0.0 2.5 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.20 EXF79036.1 - 9.6e-05 22.3 0.0 0.00023 21.1 0.0 1.8 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Methyltransf_31 PF13847.1 EXF79037.1 - 2.4e-09 36.9 0.0 4e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF79037.1 - 2.1e-08 34.4 0.0 4.9e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF79037.1 - 2.7e-07 31.1 0.0 5.5e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF79037.1 - 2.9e-07 30.8 0.0 5.8e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EXF79037.1 - 1.6e-06 27.5 0.0 2.7e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_26 PF13659.1 EXF79037.1 - 2.9e-06 27.3 0.1 1.8e-05 24.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF79037.1 - 0.00074 19.9 0.0 0.0022 18.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF79037.1 - 0.0011 18.0 0.0 0.0017 17.4 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 EXF79037.1 - 0.0032 16.6 0.0 0.0087 15.1 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EXF79037.1 - 0.035 13.4 0.0 0.068 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain AMP-binding PF00501.23 EXF79038.1 - 2.8e-86 289.5 0.0 3.6e-86 289.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EXF79038.1 - 3.8e-09 37.3 0.1 8e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Ribosomal_S17 PF00366.15 EXF79039.1 - 3e-07 30.3 1.2 5.6e-07 29.5 0.8 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 GTP_EFTU_D2 PF03144.20 EXF79039.1 - 0.0083 16.2 0.3 0.4 10.8 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 AAA PF00004.24 EXF79040.1 - 1.1e-38 132.4 0.0 2e-38 131.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EXF79040.1 - 1.4e-07 31.2 0.0 1.1e-05 25.1 0.0 3.1 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain AAA_22 PF13401.1 EXF79040.1 - 3.7e-06 27.0 0.1 0.00012 22.2 0.1 2.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EXF79040.1 - 5.2e-05 22.3 0.0 9.6e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EXF79040.1 - 0.00086 18.1 0.0 0.0015 17.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus DUF815 PF05673.8 EXF79040.1 - 0.0015 17.4 0.0 0.0026 16.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EXF79040.1 - 0.0017 18.3 0.6 0.0017 18.3 0.4 2.5 2 1 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EXF79040.1 - 0.0018 17.7 0.0 0.0034 16.8 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.9 EXF79040.1 - 0.0023 17.6 0.0 0.007 16.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EXF79040.1 - 0.0026 16.9 0.1 0.008 15.3 0.1 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 EXF79040.1 - 0.0034 16.9 1.7 0.021 14.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EXF79040.1 - 0.0051 16.7 0.0 0.032 14.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.9 EXF79040.1 - 0.0054 16.6 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EXF79040.1 - 0.0056 16.4 0.2 0.025 14.3 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_33 PF13671.1 EXF79040.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EXF79040.1 - 0.022 15.5 0.3 0.12 13.1 0.0 2.4 3 0 0 3 3 2 0 AAA domain AAA_24 PF13479.1 EXF79040.1 - 0.031 13.8 0.0 0.069 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EXF79040.1 - 0.039 13.3 0.1 0.21 10.9 0.1 2.1 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.1 EXF79040.1 - 0.05 13.5 0.6 0.18 11.7 0.0 2.2 3 0 0 3 3 2 0 AAA domain NACHT PF05729.7 EXF79040.1 - 0.082 12.5 0.0 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.11 EXF79040.1 - 0.089 12.0 0.1 0.31 10.2 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein KaiC PF06745.8 EXF79040.1 - 0.25 10.4 0.2 3.3 6.7 0.0 2.6 2 1 1 3 3 3 0 KaiC COG6 PF06419.6 EXF79041.1 - 2.2e-221 736.3 2.8 2.5e-221 736.1 1.9 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 RmuC PF02646.11 EXF79041.1 - 0.002 17.0 0.2 0.002 17.0 0.1 2.3 2 0 0 2 2 2 1 RmuC family COG2 PF06148.6 EXF79041.1 - 0.038 13.8 3.3 0.042 13.7 0.1 2.7 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF948 PF06103.6 EXF79041.1 - 0.31 10.9 1.5 2.7 7.8 0.1 3.1 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) COG5 PF10392.4 EXF79041.1 - 1 9.3 6.1 0.39 10.6 0.1 3.2 4 0 0 4 4 4 0 Golgi transport complex subunit 5 APG9 PF04109.11 EXF79042.1 - 3.2e-152 506.7 4.4 4.2e-152 506.3 3.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 BTB_2 PF02214.17 EXF79043.1 - 3e-06 27.3 0.1 0.0046 17.1 0.0 2.4 2 0 0 2 2 2 2 BTB/POZ domain Med3 PF11593.3 EXF79043.1 - 4.9 6.2 9.1 0.53 9.4 1.1 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Fungal_trans PF04082.13 EXF79044.1 - 3.6e-13 48.9 0.0 6.5e-13 48.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF79044.1 - 2.6e-07 30.4 15.1 4.4e-07 29.7 10.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.1 EXF79045.1 - 8e-23 81.3 0.0 1e-22 81.0 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EXF79045.1 - 4.9e-05 22.7 0.0 7.5e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EXF79045.1 - 0.059 12.7 0.0 0.095 12.1 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3123 PF11321.3 EXF79046.1 - 4.4 7.6 10.1 0.51 10.6 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3123) DUF3632 PF12311.3 EXF79047.1 - 4e-11 43.0 0.2 1e-10 41.7 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) Terpene_synth_C PF03936.11 EXF79047.1 - 2.2e-08 33.6 0.0 5.6e-08 32.3 0.0 1.6 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain TRI5 PF06330.6 EXF79047.1 - 0.028 13.0 0.0 0.043 12.4 0.0 1.2 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) Glyco_transf_41 PF13844.1 EXF79048.1 - 1.2e-96 323.4 0.4 1.5e-50 171.5 0.0 3.5 2 1 1 3 3 3 2 Glycosyl transferase family 41 TPR_11 PF13414.1 EXF79048.1 - 1.9e-23 81.8 2.1 5.1e-07 29.2 0.0 4.8 4 0 0 4 4 4 3 TPR repeat TPR_1 PF00515.23 EXF79048.1 - 7.6e-21 72.8 1.3 0.0011 18.5 0.0 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_2 PF07719.12 EXF79048.1 - 5.7e-19 66.4 1.4 0.017 14.9 0.1 6.7 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.1 EXF79048.1 - 1.5e-12 47.2 2.8 1.4e-06 28.1 0.1 3.9 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EXF79048.1 - 4.8e-12 44.7 0.1 0.0025 17.4 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EXF79048.1 - 3.2e-11 42.8 0.3 0.068 13.8 0.0 5.8 3 2 2 5 5 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EXF79048.1 - 4.6e-10 39.8 0.3 0.053 14.2 0.0 4.9 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EXF79048.1 - 6.7e-10 38.3 0.2 0.017 15.2 0.0 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EXF79048.1 - 1.7e-07 30.4 1.0 0.0072 16.0 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EXF79048.1 - 1.6e-05 25.1 1.2 0.37 11.1 0.1 3.9 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.1 EXF79048.1 - 2.1e-05 24.2 1.4 2 8.4 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EXF79048.1 - 0.00031 20.5 1.9 0.72 9.7 0.0 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat NARP1 PF12569.3 EXF79048.1 - 0.0076 15.0 0.0 0.41 9.3 0.0 2.1 2 0 0 2 2 2 1 NMDA receptor-regulated protein 1 TPR_6 PF13174.1 EXF79048.1 - 0.02 15.2 0.0 43 4.8 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF237 PF03072.9 EXF79048.1 - 0.17 11.7 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 MG032/MG096/MG288 family 1 Ribosomal_L11_N PF03946.9 EXF79049.1 - 7.3e-18 63.7 0.1 1.1e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EXF79049.1 - 3.6e-11 43.0 0.2 5.8e-11 42.3 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Sec23_trunk PF04811.10 EXF79050.1 - 3.4e-78 262.3 0.0 4.8e-78 261.8 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EXF79050.1 - 1.3e-34 117.6 1.1 3.8e-34 116.2 0.1 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EXF79050.1 - 5.1e-31 107.0 0.3 1.1e-30 106.0 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EXF79050.1 - 1.4e-15 56.5 6.3 2.9e-15 55.5 4.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EXF79050.1 - 6.7e-12 44.9 0.0 1.9e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat FUSC PF04632.7 EXF79051.1 - 5.2 5.3 6.9 10 4.3 1.9 2.4 2 0 0 2 2 2 0 Fusaric acid resistance protein family MFS_1 PF07690.11 EXF79052.1 - 3e-45 154.4 39.5 7.8e-42 143.2 20.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF79052.1 - 2.4e-10 39.6 12.0 2.4e-10 39.6 8.3 2.8 4 0 0 4 4 4 1 Sugar (and other) transporter DUF3754 PF12576.3 EXF79052.1 - 2.4 7.8 3.9 0.63 9.6 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3754) Lipase_GDSL_2 PF13472.1 EXF79053.1 - 1.5e-17 64.3 0.9 2e-17 63.9 0.6 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EXF79053.1 - 4.1e-09 36.6 0.8 6.9e-09 35.8 0.6 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DHquinase_I PF01487.10 EXF79053.1 - 0.0089 15.6 0.0 0.014 15.0 0.0 1.2 1 0 0 1 1 1 1 Type I 3-dehydroquinase DUF3328 PF11807.3 EXF79055.1 - 5.2e-44 150.5 0.8 7.1e-44 150.0 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF2636 PF11120.3 EXF79056.1 - 0.00011 21.5 0.6 24 4.5 0.0 5.0 5 0 0 5 5 5 1 Protein of unknown function (DUF2636) PGA_cap PF09587.5 EXF79056.1 - 0.019 14.3 1.8 0.22 10.8 0.2 2.1 1 1 1 2 2 2 0 Bacterial capsule synthesis protein PGA_cap COX_ARM PF06481.9 EXF79056.1 - 0.053 13.2 0.6 41 3.9 0.0 3.2 3 0 0 3 3 3 0 COX Aromatic Rich Motif Ribosomal_S11 PF00411.14 EXF79056.1 - 0.11 12.6 0.8 1.3 9.2 0.1 2.4 2 0 0 2 2 2 0 Ribosomal protein S11 BRF1 PF07741.8 EXF79056.1 - 6.6 7.0 13.4 4.5 7.5 0.9 2.6 1 1 1 2 2 2 0 Brf1-like TBP-binding domain Bac_rhamnosid PF05592.6 EXF79057.1 - 1.1e-178 594.6 0.0 1.9e-178 593.8 0.0 1.4 2 0 0 2 2 2 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 EXF79057.1 - 2.3e-54 183.4 0.2 4.2e-54 182.6 0.1 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Glyco_transf_28 PF03033.15 EXF79057.1 - 7e-22 77.6 0.0 1.6e-21 76.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EXF79057.1 - 4.6e-05 22.1 0.1 7.5e-05 21.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase DUF2786 PF10979.3 EXF79057.1 - 0.083 12.6 1.1 0.19 11.5 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2786) Glyco_tran_28_C PF04101.11 EXF79057.1 - 0.16 11.5 0.0 0.34 10.5 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain DUF4106 PF13388.1 EXF79057.1 - 0.23 10.3 5.1 0.38 9.6 3.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) ketoacyl-synt PF00109.21 EXF79058.1 - 1.7e-78 263.6 0.7 8.1e-78 261.4 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EXF79058.1 - 1.3e-56 191.1 0.3 3.7e-56 189.6 0.2 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 EXF79058.1 - 1.9e-52 178.6 0.2 4.7e-51 174.0 0.2 2.2 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 EXF79058.1 - 2.8e-51 174.4 0.2 5.1e-51 173.6 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EXF79058.1 - 1.2e-44 152.1 2.1 2.7e-43 147.7 0.4 3.1 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EXF79058.1 - 2e-35 121.1 0.8 8e-35 119.2 0.0 2.5 3 0 0 3 3 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EXF79058.1 - 4.1e-20 72.1 0.0 1.8e-19 70.0 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF79058.1 - 1.9e-12 47.1 0.0 5.1e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF79058.1 - 1.7e-10 40.6 0.0 4.2e-10 39.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF79058.1 - 4.1e-09 36.8 0.0 1.6e-08 34.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EXF79058.1 - 1.7e-08 34.6 0.1 4.4e-08 33.2 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 EXF79058.1 - 1.8e-08 34.9 0.0 9.5e-08 32.6 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EXF79058.1 - 1.9e-07 30.7 0.0 6.3e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ubie_methyltran PF01209.13 EXF79058.1 - 2.3e-06 26.8 0.0 4.6e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EXF79058.1 - 3e-06 27.5 0.0 1.5e-05 25.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.18 EXF79058.1 - 0.00033 19.7 0.7 0.0015 17.5 0.0 2.3 3 0 0 3 3 3 1 Thiolase, N-terminal domain PCMT PF01135.14 EXF79058.1 - 0.0056 16.2 0.0 0.014 14.9 0.0 1.6 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.4 EXF79058.1 - 0.11 11.9 0.0 0.26 10.7 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.15 EXF79058.1 - 0.33 9.9 0.0 2.2 7.2 0.0 2.1 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Thioredoxin_5 PF13743.1 EXF79058.1 - 0.37 10.3 0.0 0.75 9.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Methyltransf_23 PF13489.1 EXF79059.1 - 2.4e-10 40.3 0.0 3.6e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF79059.1 - 0.0027 18.2 0.0 0.023 15.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF79059.1 - 0.0027 18.1 0.0 0.0051 17.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF79059.1 - 0.0079 16.6 0.0 0.039 14.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF79059.1 - 0.015 14.9 0.0 0.09 12.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain PTS_2-RNA PF01885.11 EXF79059.1 - 0.061 12.6 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family CT47 PF15623.1 EXF79059.1 - 0.66 9.6 3.7 1 9.0 2.6 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 Methyltransf_23 PF13489.1 EXF79060.1 - 1.4e-06 28.1 0.0 2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF79060.1 - 2.9e-06 27.6 0.0 5.8e-06 26.7 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF79060.1 - 8.8e-05 22.9 0.0 0.00016 22.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF79060.1 - 0.00019 21.9 0.0 0.00031 21.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF79060.1 - 0.0061 16.5 0.0 0.0078 16.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF79060.1 - 0.0067 16.7 0.0 0.01 16.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF79060.1 - 0.025 13.9 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Sugar_tr PF00083.19 EXF79061.1 - 1.4e-101 340.2 29.3 1.7e-101 340.0 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF79061.1 - 1.4e-32 112.7 26.7 1.4e-32 112.7 18.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily HK PF02110.10 EXF79061.1 - 0.088 11.9 0.2 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Hydroxyethylthiazole kinase family Glyco_hydro_11 PF00457.12 EXF79062.1 - 1.4e-81 272.2 23.1 1.6e-81 272.0 16.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Ank_2 PF12796.2 EXF79063.1 - 1.6e-18 66.8 0.1 1.2e-08 35.1 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EXF79063.1 - 4.1e-14 51.5 0.8 0.084 12.7 0.0 5.7 6 1 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.1 EXF79063.1 - 6.2e-11 41.4 0.6 0.0066 16.5 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EXF79063.1 - 1.5e-10 41.2 0.1 0.00054 20.4 0.0 4.1 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF79063.1 - 1.6e-10 40.8 0.5 0.094 13.0 0.0 4.7 3 2 2 5 5 5 3 Ankyrin repeats (many copies) ADH_zinc_N PF00107.21 EXF79065.1 - 4.1e-22 78.1 0.0 6.2e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF79065.1 - 4.2e-06 27.6 0.0 8.8e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Aldo_ket_red PF00248.16 EXF79065.1 - 0.037 12.8 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Aldo/keto reductase family PCP_red PF08369.5 EXF79066.1 - 0.012 15.4 1.0 0.037 13.8 0.7 1.8 1 0 0 1 1 1 0 Proto-chlorophyllide reductase 57 kD subunit HABP4_PAI-RBP1 PF04774.10 EXF79066.1 - 0.53 10.8 3.2 0.74 10.3 0.2 2.3 2 0 0 2 2 2 0 Hyaluronan / mRNA binding family Oxidored_FMN PF00724.15 EXF79067.1 - 3e-88 296.1 0.0 3.4e-88 295.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MFS_1 PF07690.11 EXF79068.1 - 8e-26 90.5 37.0 1.9e-16 59.7 20.5 3.3 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF79068.1 - 4.2e-11 41.7 11.5 8.7e-09 34.1 3.2 2.3 1 1 1 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Polysacc_deac_1 PF01522.16 EXF79069.1 - 3.4e-11 42.8 0.0 5.6e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Fungal_trans PF04082.13 EXF79070.1 - 1.6e-32 112.4 0.4 2.8e-32 111.6 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Transp_cyt_pur PF02133.10 EXF79071.1 - 3.7e-87 292.7 43.4 4.3e-87 292.4 30.1 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Amidase PF01425.16 EXF79072.1 - 1.1e-73 248.5 0.0 1.3e-73 248.3 0.0 1.1 1 0 0 1 1 1 1 Amidase Aminotran_1_2 PF00155.16 EXF79073.1 - 2.4e-16 59.6 0.0 3e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EXF79073.1 - 0.00014 20.5 0.0 0.0039 15.8 0.0 2.4 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 EXF79073.1 - 0.15 11.0 0.0 1.8 7.4 0.0 2.1 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family PhoU PF01895.14 EXF79074.1 - 0.072 13.5 0.1 16 6.0 0.0 2.5 2 0 0 2 2 2 0 PhoU domain TPP_enzyme_N PF02776.13 EXF79075.1 - 4.8e-34 117.3 0.7 8e-34 116.5 0.5 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EXF79075.1 - 8.7e-18 64.3 0.0 1.8e-16 60.1 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EXF79075.1 - 4.7e-16 58.7 0.0 9.6e-16 57.7 0.0 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain ADH_zinc_N PF00107.21 EXF79076.1 - 1.1e-09 37.8 0.0 2.3e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF79076.1 - 0.0053 16.5 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 EXF79076.1 - 0.046 14.3 0.0 0.11 13.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain NmrA PF05368.8 EXF79076.1 - 0.14 11.4 0.1 0.19 10.9 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family HET PF06985.6 EXF79077.1 - 4.9e-31 107.7 0.0 8.3e-31 107.0 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Zip PF02535.17 EXF79078.1 - 1.2e-24 86.8 37.1 6.4e-12 45.1 1.7 3.5 3 1 1 4 4 4 3 ZIP Zinc transporter PSI_PsaJ PF01701.13 EXF79078.1 - 0.097 12.4 0.9 0.47 10.2 0.6 2.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit IX / PsaJ LEA_6 PF10714.4 EXF79079.1 - 0.78 9.5 5.8 0.09 12.5 1.2 1.5 2 0 0 2 2 2 0 Late embryogenesis abundant protein 18 MFS_1 PF07690.11 EXF79080.1 - 7.1e-29 100.6 33.1 4.1e-28 98.0 16.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TraL PF07178.6 EXF79080.1 - 1.9 8.5 6.5 0.39 10.7 0.6 2.7 3 0 0 3 3 3 0 TraL protein 2OG-FeII_Oxy PF03171.15 EXF79081.1 - 1.1e-13 51.3 0.0 1.9e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EXF79081.1 - 1.5e-13 51.3 0.0 3.6e-13 50.0 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal HET PF06985.6 EXF79082.1 - 2e-12 47.4 0.0 3.9e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) BNR PF02012.15 EXF79083.1 - 0.71 9.9 6.5 3.6 7.8 0.1 3.2 3 0 0 3 3 3 0 BNR/Asp-box repeat FAD_binding_4 PF01565.18 EXF79084.1 - 2.7e-15 56.0 3.1 1e-14 54.1 2.2 2.0 1 1 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF79084.1 - 8.3e-08 32.0 0.2 1.5e-07 31.1 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EXF79084.1 - 0.046 12.8 0.0 0.072 12.2 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding GST_N_3 PF13417.1 EXF79086.1 - 2.8e-12 46.6 0.1 8.3e-12 45.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EXF79086.1 - 4.2e-08 33.0 0.0 8.3e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EXF79086.1 - 7.9e-08 32.3 0.0 1.4e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EXF79086.1 - 1.4e-06 28.2 0.0 2.4e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EXF79086.1 - 7.6e-05 22.5 0.0 0.00017 21.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FAA_hydrolase PF01557.13 EXF79087.1 - 7.8e-51 172.5 0.0 1.1e-50 172.1 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EXF79087.1 - 2.8e-27 94.8 0.0 7.2e-27 93.4 0.0 1.7 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Zn_clus PF00172.13 EXF79088.1 - 0.00036 20.3 3.7 0.00053 19.8 2.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RIC3 PF15361.1 EXF79088.1 - 0.051 13.8 1.1 0.1 12.8 0.0 2.0 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Fungal_trans PF04082.13 EXF79089.1 - 6e-21 74.4 0.1 1.1e-20 73.6 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EXF79090.1 - 1.2e-33 116.2 13.0 1.2e-33 116.2 9.0 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF997 PF06196.7 EXF79090.1 - 0.2 11.1 3.3 0.31 10.5 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF997) DUF4179 PF13786.1 EXF79090.1 - 1.5 9.1 4.5 9.5 6.5 0.6 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4179) DUF4341 PF14241.1 EXF79090.1 - 4.9 6.9 7.3 4.3 7.0 0.1 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF4341) AAA_17 PF13207.1 EXF79091.1 - 4.5e-05 24.2 0.0 0.00013 22.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EXF79091.1 - 0.00026 20.8 0.0 0.0006 19.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EXF79091.1 - 0.0021 17.7 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.7 EXF79091.1 - 0.0042 16.1 0.0 0.0073 15.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 EXF79091.1 - 0.0072 16.3 0.0 0.013 15.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EXF79091.1 - 0.027 14.7 0.2 0.08 13.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EXF79091.1 - 0.031 13.8 0.0 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain ArgK PF03308.11 EXF79091.1 - 0.063 12.0 0.0 0.093 11.4 0.0 1.2 1 0 0 1 1 1 0 ArgK protein KTI12 PF08433.5 EXF79091.1 - 0.15 11.2 0.0 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Torsin PF06309.6 EXF79091.1 - 0.17 11.7 0.0 0.38 10.6 0.0 1.5 1 0 0 1 1 1 0 Torsin Iso_dh PF00180.15 EXF79092.1 - 2.9e-88 296.1 0.0 3.2e-88 296.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SAM_2 PF07647.12 EXF79092.1 - 0.13 12.1 0.0 0.35 10.7 0.0 1.7 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) MFS_Mycoplasma PF07672.8 EXF79093.1 - 0.0087 15.2 0.2 0.0087 15.2 0.1 2.1 2 0 0 2 2 2 1 Mycoplasma MFS transporter Neisseria_TspB PF05616.8 EXF79093.1 - 0.61 8.4 3.8 1 7.6 2.6 1.2 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein MFS_1 PF07690.11 EXF79094.1 - 1.4e-32 112.7 39.2 2e-32 112.2 26.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily QueF_N PF14819.1 EXF79098.1 - 0.0051 16.8 0.0 0.0076 16.3 0.0 1.2 1 0 0 1 1 1 1 Nitrile reductase, 7-cyano-7-deazaguanine-reductase N-term PhyH PF05721.8 EXF79099.1 - 2.9e-05 24.1 0.1 0.00012 22.2 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) p450 PF00067.17 EXF79100.1 - 7.7e-29 100.5 0.0 9.5e-29 100.2 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Pyr_redox_3 PF13738.1 EXF79101.1 - 8.8e-16 58.5 0.0 1.5e-15 57.8 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EXF79101.1 - 7e-12 44.3 0.0 1.5e-11 43.2 0.0 1.4 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EXF79101.1 - 1.7e-07 31.1 0.0 5.3e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EXF79101.1 - 0.012 15.3 0.0 0.027 14.2 0.0 1.7 1 1 0 1 1 1 0 FAD-NAD(P)-binding p450 PF00067.17 EXF79102.1 - 7.5e-48 163.1 0.0 1.3e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.10 EXF79104.1 - 1.5e-05 23.6 0.0 0.00013 20.5 0.0 2.1 1 1 0 1 1 1 1 Transferase family PSK_trans_fac PF07704.6 EXF79104.1 - 0.077 13.6 0.5 0.077 13.6 0.4 2.2 2 0 0 2 2 2 0 Rv0623-like transcription factor Ilar_coat PF01787.11 EXF79105.1 - 0.13 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Ilarvirus coat protein DUF4184 PF13803.1 EXF79106.1 - 0.0071 15.6 1.0 0.89 8.8 0.0 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4184) DUF1673 PF07895.6 EXF79106.1 - 0.064 12.7 0.3 0.36 10.3 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1673) Corona_S2 PF01601.11 EXF79106.1 - 0.16 10.0 0.2 0.21 9.6 0.2 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein FA_desaturase PF00487.19 EXF79106.1 - 0.74 9.1 7.6 1.8 7.9 5.3 1.8 1 1 0 1 1 1 0 Fatty acid desaturase Bac_rhamnosid PF05592.6 EXF79108.1 - 7.1e-24 83.8 0.2 3.6e-21 74.9 0.3 3.0 2 1 0 2 2 2 2 Bacterial alpha-L-rhamnosidase DEC-1_N PF04625.8 EXF79108.1 - 3 6.4 6.0 4.5 5.8 4.2 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Fungal_trans PF04082.13 EXF79110.1 - 2.7e-10 39.5 0.3 4.6e-10 38.7 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_S10 PF00450.17 EXF79112.1 - 2.4e-89 300.3 0.0 3e-89 300.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase DUF1680 PF07944.7 EXF79113.1 - 6.2e-16 57.7 0.0 1.6e-14 53.1 0.0 2.1 2 0 0 2 2 2 2 Putative glycosyl hydrolase of unknown function (DUF1680) MFS_1 PF07690.11 EXF79114.1 - 1.4e-37 129.2 34.1 1.4e-37 129.2 23.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily 7TM_GPCR_Srz PF10325.4 EXF79114.1 - 0.93 8.5 6.0 1.4 7.9 0.1 2.3 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srz Fungal_trans PF04082.13 EXF79115.1 - 2e-21 76.0 0.0 2.8e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF79115.1 - 3.8e-08 33.1 13.8 7e-08 32.2 9.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyoxalase PF00903.20 EXF79116.1 - 1.8e-13 50.5 0.0 3e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EXF79116.1 - 5.4e-08 33.4 0.0 8.1e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase-like domain Abhydrolase_8 PF06259.7 EXF79116.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase adh_short PF00106.20 EXF79118.1 - 1.4e-18 67.3 0.5 3e-16 59.7 0.4 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF79118.1 - 5.1e-06 26.4 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EXF79118.1 - 0.00029 20.8 0.1 0.0047 16.9 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EXF79118.1 - 0.00048 19.8 0.2 0.0035 17.0 0.1 2.0 1 1 0 1 1 1 1 KR domain Amidase PF01425.16 EXF79119.1 - 1.4e-33 116.4 3.0 4.6e-33 114.7 2.1 1.9 1 1 0 1 1 1 1 Amidase Amino_oxidase PF01593.19 EXF79120.1 - 1.2e-30 106.9 0.5 8.7e-30 104.1 0.4 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EXF79120.1 - 3.6e-07 30.1 0.0 8.3e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EXF79120.1 - 8.5e-05 22.7 0.0 0.00021 21.4 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EXF79120.1 - 0.0054 15.8 0.1 0.0098 14.9 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF79120.1 - 0.0071 15.2 0.2 0.02 13.8 0.3 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EXF79120.1 - 0.12 11.3 0.2 0.25 10.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family MFS_1 PF07690.11 EXF79121.1 - 3.6e-29 101.5 47.2 2.8e-15 55.9 16.7 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF79121.1 - 6e-14 51.1 23.4 5.9e-13 47.8 16.2 1.9 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EXF79121.1 - 3.4e-08 32.4 7.7 3.4e-08 32.4 5.3 4.3 3 2 2 5 5 5 1 Sugar (and other) transporter WGG PF10273.4 EXF79121.1 - 0.069 13.2 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Pre-rRNA-processing protein TSR2 PALP PF00291.20 EXF79122.1 - 1.6e-22 80.1 0.0 1.6e-19 70.2 0.0 2.2 2 0 0 2 2 2 2 Pyridoxal-phosphate dependent enzyme Rhodanese PF00581.15 EXF79122.1 - 4.2e-09 36.7 0.0 8.4e-08 32.5 0.0 2.5 2 0 0 2 2 2 1 Rhodanese-like domain MFS_1 PF07690.11 EXF79123.1 - 1.4e-24 86.4 38.8 3.5e-23 81.8 25.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.14 EXF79124.1 - 1.5e-64 218.2 0.0 2.1e-64 217.8 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EXF79124.1 - 0.0039 17.5 0.0 0.012 16.0 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF79124.1 - 0.012 15.4 0.0 0.38 10.6 0.0 2.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF79124.1 - 0.21 10.0 0.0 0.42 9.0 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein p450 PF00067.17 EXF79125.1 - 5e-61 206.6 0.0 1.2e-60 205.3 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 Nitroreductase PF00881.19 EXF79126.1 - 1.7e-13 50.7 0.0 2.3e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Nitroreductase family MFS_1 PF07690.11 EXF79127.1 - 4.1e-42 144.1 44.8 6.7e-42 143.4 29.7 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Ribonuc_L-PSP PF01042.16 EXF79127.1 - 1.1e-12 47.7 0.0 2.2e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Endoribonuclease L-PSP Sugar_tr PF00083.19 EXF79128.1 - 2.8e-87 293.1 21.2 3.2e-87 292.9 14.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF79128.1 - 1.6e-19 69.8 29.7 2.9e-13 49.2 8.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MLTD_N PF06474.7 EXF79128.1 - 0.084 13.0 0.7 0.24 11.6 0.5 1.9 1 0 0 1 1 1 0 MltD lipid attachment motif ADH_N PF08240.7 EXF79129.1 - 1.2e-18 66.8 0.1 2.1e-18 66.0 0.1 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF79129.1 - 5.2e-09 35.7 0.2 5.2e-09 35.7 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF79129.1 - 0.014 16.3 0.0 0.036 14.9 0.0 1.7 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Fungal_trans PF04082.13 EXF79131.1 - 6.2e-28 97.3 0.0 1.4e-27 96.1 0.0 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF79131.1 - 3.2e-09 36.5 7.6 5.1e-09 35.8 5.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4306 PF14154.1 EXF79131.1 - 0.047 13.6 0.2 0.093 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) Fungal_trans PF04082.13 EXF79132.1 - 2.2e-26 92.2 0.2 3.6e-26 91.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF79132.1 - 9e-08 31.9 7.7 1.6e-07 31.1 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF79134.1 - 4.9e-26 91.1 0.0 8.9e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF79134.1 - 1.7e-09 37.3 10.9 2.7e-09 36.7 7.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ExbD PF02472.11 EXF79136.1 - 0.072 13.0 4.3 0.077 12.9 1.0 2.1 2 0 0 2 2 2 0 Biopolymer transport protein ExbD/TolR MIase PF02426.11 EXF79136.1 - 0.15 11.9 1.1 0.48 10.2 0.0 2.3 2 1 0 2 2 2 0 Muconolactone delta-isomerase Ribosomal_S17 PF00366.15 EXF79137.1 - 4.8e-30 103.4 0.6 7e-30 102.8 0.4 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Spc7_N PF15402.1 EXF79138.1 - 7.6e-244 811.8 103.8 6e-132 441.5 40.7 4.1 2 1 1 3 3 3 2 N-terminus of kinetochore NMS complex subunit Spc7 Spc7 PF08317.6 EXF79138.1 - 4.4e-119 396.9 8.0 4.4e-119 396.9 5.6 1.6 2 0 0 2 2 2 1 Spc7 kinetochore protein Spc7_C2 PF15577.1 EXF79138.1 - 6.2e-19 67.4 0.3 1.2e-18 66.4 0.2 1.5 1 0 0 1 1 1 1 Spc7_C2 DUF607 PF04678.8 EXF79138.1 - 0.31 10.9 1.8 1.1 9.1 1.2 2.0 1 0 0 1 1 1 0 Protein of unknown function, DUF607 Laminin_II PF06009.7 EXF79138.1 - 0.39 10.4 8.2 2 8.1 4.1 2.9 2 1 1 3 3 3 0 Laminin Domain II V_ATPase_I PF01496.14 EXF79138.1 - 2.4 5.9 3.8 4.2 5.0 2.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.4 EXF79138.1 - 2.4 7.0 15.5 1.3 7.9 4.3 2.6 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Phytoreo_S7 PF07236.6 EXF79139.1 - 0.13 10.5 1.6 0.2 9.9 1.1 1.2 1 0 0 1 1 1 0 Phytoreovirus S7 protein Atg14 PF10186.4 EXF79140.1 - 6.5e-78 261.7 0.0 7.6e-78 261.5 0.0 1.0 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 M_domain PF12938.2 EXF79140.1 - 0.13 12.0 0.4 0.25 11.1 0.3 1.4 1 0 0 1 1 1 0 M domain of GW182 THOC7 PF05615.8 EXF79140.1 - 0.23 11.7 3.4 0.42 10.8 2.3 1.4 1 0 0 1 1 1 0 Tho complex subunit 7 Mnd1 PF03962.10 EXF79140.1 - 2.5 7.7 4.9 3.6 7.1 3.1 1.4 1 1 0 1 1 1 0 Mnd1 family RGCC PF15151.1 EXF79141.1 - 0.11 12.9 0.7 1.3 9.4 0.1 2.1 1 1 1 2 2 2 0 Response gene to complement 32 protein family DUF3807 PF12720.2 EXF79142.1 - 2.3e-31 109.2 0.8 2.8e-31 109.0 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3807) Pkinase PF00069.20 EXF79143.1 - 4.6e-52 176.7 0.1 6e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF79143.1 - 5.5e-13 48.5 0.0 9e-13 47.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EXF79143.1 - 0.028 14.1 0.0 9.9 5.8 0.1 2.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Aconitase_B_N PF11791.3 EXF79143.1 - 0.084 12.6 0.1 0.18 11.6 0.0 1.5 2 0 0 2 2 2 0 Aconitate B N-terminal domain Scm3 PF10384.4 EXF79144.1 - 1.4e-18 66.0 0.0 3.8e-18 64.7 0.0 1.8 1 0 0 1 1 1 1 Centromere protein Scm3 APG6 PF04111.7 EXF79145.1 - 1e-127 425.5 0.0 1.3e-127 425.2 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg6 zf-C4H2 PF10146.4 EXF79145.1 - 0.039 13.9 7.1 0.087 12.8 4.9 1.5 1 0 0 1 1 1 0 Zinc finger-containing protein Pertus-S4-tox PF09275.5 EXF79145.1 - 0.065 13.3 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Pertussis toxin S4 subunit IncA PF04156.9 EXF79145.1 - 1.1 8.8 11.5 2.5 7.6 8.0 1.6 1 0 0 1 1 1 0 IncA protein V_ATPase_I PF01496.14 EXF79145.1 - 1.4 6.6 6.4 1.9 6.2 4.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA PF00004.24 EXF79146.1 - 3.5e-12 46.6 0.0 8.4e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EXF79146.1 - 5.9e-05 23.1 0.1 0.00014 21.8 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EXF79146.1 - 0.01 16.0 0.1 0.031 14.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EXF79146.1 - 0.01 15.5 0.1 0.058 13.1 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_14 PF13173.1 EXF79146.1 - 0.04 13.8 0.0 0.12 12.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EXF79146.1 - 0.041 13.5 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) CPT PF07931.7 EXF79146.1 - 0.067 12.8 0.0 0.28 10.8 0.0 1.9 1 1 1 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_17 PF13207.1 EXF79146.1 - 0.094 13.5 0.6 0.47 11.2 0.1 2.5 2 1 0 2 2 2 0 AAA domain Trypan_PARP PF05887.6 EXF79148.1 - 0.27 11.0 9.4 0.38 10.5 6.5 1.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) WD40 PF00400.27 EXF79149.1 - 3.3e-29 99.6 14.9 3.8e-08 32.9 0.0 6.7 7 1 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EXF79149.1 - 1.5e-05 24.7 0.3 0.043 13.5 0.0 3.3 3 0 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A HIRA_B PF09453.5 EXF79149.1 - 0.32 10.6 4.8 0.097 12.2 0.7 2.2 2 0 0 2 2 2 0 HIRA B motif Abhydrolase_6 PF12697.2 EXF79150.1 - 1.4e-25 90.4 0.1 3.3e-25 89.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF79150.1 - 5.9e-16 58.5 0.0 2.3e-15 56.6 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF79150.1 - 9.5e-14 51.4 0.0 2.7e-13 50.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DSPc PF00782.15 EXF79150.1 - 1.9e-11 43.6 0.0 3.3e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Thioesterase PF00975.15 EXF79150.1 - 3.6e-06 27.3 0.0 7.7e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.8 EXF79150.1 - 1.6e-05 24.6 0.0 8.1e-05 22.3 0.0 2.0 2 0 0 2 2 2 1 PGAP1-like protein PTPlike_phytase PF14566.1 EXF79150.1 - 0.00014 21.9 0.0 0.00024 21.1 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.22 EXF79150.1 - 0.00061 19.2 0.0 0.001 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Abhydrolase_3 PF07859.8 EXF79150.1 - 0.0023 17.5 0.0 0.0048 16.5 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF2305 PF10230.4 EXF79150.1 - 0.0037 16.7 0.0 0.0068 15.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) VirJ PF06057.6 EXF79150.1 - 0.0061 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Hydrolase_4 PF12146.3 EXF79150.1 - 0.0088 15.8 0.0 0.027 14.2 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase DUF3089 PF11288.3 EXF79150.1 - 0.018 14.2 0.0 0.035 13.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Thiolase_C PF02803.13 EXF79150.1 - 0.026 13.9 0.1 2.2 7.7 0.0 2.8 3 0 0 3 3 3 0 Thiolase, C-terminal domain DUF900 PF05990.7 EXF79150.1 - 0.027 13.8 0.0 0.043 13.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.20 EXF79150.1 - 0.028 14.0 0.0 0.11 12.0 0.0 1.9 1 1 1 2 2 2 0 Lipase (class 3) Chlorophyllase2 PF12740.2 EXF79150.1 - 0.036 12.9 0.0 0.065 12.1 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Esterase PF00756.15 EXF79150.1 - 0.088 12.2 0.0 1 8.7 0.0 2.2 2 0 0 2 2 2 0 Putative esterase LCAT PF02450.10 EXF79150.1 - 0.14 11.0 0.0 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF498 PF04430.9 EXF79151.1 - 9.9e-28 95.8 0.0 1.3e-27 95.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) Ribosomal_L34e PF01199.13 EXF79152.1 - 2.8e-36 123.6 2.6 2.8e-36 123.6 1.8 2.0 2 1 0 2 2 2 1 Ribosomal protein L34e FhuF_C PF11575.3 EXF79152.1 - 7.3 6.3 6.7 6 6.6 0.2 2.7 3 0 0 3 3 3 0 FhuF 2Fe-2S C-terminal domain FAR1 PF03101.10 EXF79153.1 - 0.00012 22.4 0.1 0.00022 21.6 0.1 1.3 1 0 0 1 1 1 1 FAR1 DNA-binding domain XhlA PF10779.4 EXF79153.1 - 0.019 14.8 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Haemolysin XhlA Hemagglutinin PF00509.13 EXF79153.1 - 0.026 12.6 0.0 0.038 12.1 0.0 1.1 1 0 0 1 1 1 0 Haemagglutinin AFT PF08731.6 EXF79153.1 - 0.03 14.5 0.1 0.049 13.8 0.1 1.3 1 0 0 1 1 1 0 Transcription factor AFT Tropomyosin_1 PF12718.2 EXF79153.1 - 0.059 13.2 0.0 0.096 12.5 0.0 1.2 1 0 0 1 1 1 0 Tropomyosin like Tektin PF03148.9 EXF79153.1 - 0.12 10.9 0.1 0.16 10.4 0.0 1.1 1 0 0 1 1 1 0 Tektin family Alk_phosphatase PF00245.15 EXF79154.1 - 6e-107 357.9 0.0 7.4e-107 357.6 0.0 1.1 1 0 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EXF79154.1 - 0.00037 19.9 0.3 0.0018 17.6 0.0 2.1 2 0 0 2 2 2 1 Metalloenzyme superfamily S_100 PF01023.14 EXF79154.1 - 0.025 13.8 0.1 0.063 12.6 0.1 1.6 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Phage_Mu_Gam PF07352.7 EXF79154.1 - 0.079 12.4 0.5 0.82 9.1 0.0 2.2 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein LRR_4 PF12799.2 EXF79155.1 - 0.0028 17.2 0.9 8.2 6.1 0.0 5.1 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) Rad9 PF04139.8 EXF79156.1 - 2.2e-67 226.8 0.0 2.6e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 Rad9 RCC1 PF00415.13 EXF79157.1 - 2.6e-30 104.3 11.3 2.2e-10 40.5 0.0 7.5 7 1 1 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EXF79157.1 - 9e-20 69.7 20.5 3.1e-05 23.4 0.1 6.0 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat PDH PF02153.12 EXF79158.1 - 1.2e-13 50.5 0.1 1.8e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.12 EXF79158.1 - 8.2e-08 32.5 0.0 1.8e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EXF79158.1 - 1.1e-07 31.9 0.1 2.4e-07 30.7 0.0 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EXF79158.1 - 4.1e-05 22.7 0.0 7.8e-05 21.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EXF79158.1 - 0.0021 17.5 0.0 0.0036 16.7 0.0 1.5 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EXF79158.1 - 0.0048 16.5 0.3 0.048 13.3 0.0 2.2 1 1 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EXF79158.1 - 0.016 15.1 0.0 0.049 13.6 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain Mpv17_PMP22 PF04117.7 EXF79160.1 - 1.4e-13 50.2 2.2 2e-12 46.5 1.4 2.3 2 0 0 2 2 2 1 Mpv17 / PMP22 family EAP30 PF04157.11 EXF79161.1 - 4.8e-67 225.3 0.0 5.5e-67 225.1 0.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family Ribosomal_S9 PF00380.14 EXF79162.1 - 5.3e-39 133.2 0.4 6e-39 133.0 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Nckap1 PF09735.4 EXF79162.1 - 0.027 11.9 0.0 0.03 11.8 0.0 1.0 1 0 0 1 1 1 0 Membrane-associated apoptosis protein CFEM PF05730.6 EXF79163.1 - 3.1e-13 49.3 9.1 5.6e-13 48.5 6.3 1.4 1 0 0 1 1 1 1 CFEM domain Frag1 PF10277.4 EXF79167.1 - 5.8e-39 133.8 11.1 5.8e-39 133.8 7.7 3.1 3 0 0 3 3 3 1 Frag1/DRAM/Sfk1 family PsiA PF06952.6 EXF79167.1 - 0.27 10.2 4.1 0.37 9.8 1.0 2.3 2 0 0 2 2 2 0 PsiA protein U3_assoc_6 PF08640.6 EXF79168.1 - 8.7e-27 92.7 2.8 1.1e-26 92.4 0.5 2.2 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 NRDE-2 PF08424.5 EXF79168.1 - 0.0031 16.4 0.9 0.011 14.7 0.1 2.1 2 0 0 2 2 2 1 NRDE-2, necessary for RNA interference TPR_14 PF13428.1 EXF79168.1 - 0.012 16.1 0.0 7.7 7.4 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat EVE PF01878.13 EXF79169.1 - 6.7e-45 152.6 0.1 1.5e-44 151.5 0.0 1.6 1 0 0 1 1 1 1 EVE domain SRP-alpha_N PF04086.8 EXF79169.1 - 0.8 9.0 13.7 1.2 8.4 9.5 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2151 PF10221.4 EXF79169.1 - 3.1 5.8 8.1 4.5 5.3 5.6 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator MIP-T3 PF10243.4 EXF79169.1 - 9.7 4.5 28.4 16 3.7 19.7 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PALP PF00291.20 EXF79170.1 - 1.8e-56 191.6 5.5 2.3e-56 191.3 3.8 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Flavi_NS4A PF01350.12 EXF79172.1 - 0.035 13.6 0.2 0.091 12.3 0.1 1.7 1 0 0 1 1 1 0 Flavivirus non-structural protein NS4A PBP PF01161.15 EXF79173.1 - 2.1e-15 56.8 0.0 3.2e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein RdRP_4 PF02123.11 EXF79173.1 - 0.014 14.1 0.3 0.018 13.7 0.2 1.1 1 0 0 1 1 1 0 Viral RNA-directed RNA-polymerase p450 PF00067.17 EXF79174.1 - 1.3e-70 238.2 0.0 1.5e-70 238.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Amidase PF01425.16 EXF79175.1 - 1.1e-61 209.0 0.2 1.7e-34 119.4 0.2 3.1 3 0 0 3 3 3 3 Amidase Methyltransf_23 PF13489.1 EXF79176.1 - 2.7e-20 72.7 0.0 4.2e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF79176.1 - 2.5e-06 28.0 0.0 5.3e-05 23.7 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF79176.1 - 4.3e-06 27.1 0.0 1.8e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF79176.1 - 1.2e-05 25.7 0.0 2.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF79176.1 - 2.4e-05 23.9 0.0 0.00032 20.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF79176.1 - 0.031 13.3 0.0 0.31 10.1 0.0 2.3 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.4 EXF79176.1 - 0.046 13.1 0.0 0.07 12.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.1 EXF79176.1 - 0.082 13.2 0.0 0.22 11.8 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain DUF3592 PF12158.3 EXF79176.1 - 0.092 12.5 0.4 0.15 11.8 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3592) Trypan_PARP PF05887.6 EXF79176.1 - 9.6 6.0 11.7 17 5.2 8.1 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Sugar_tr PF00083.19 EXF79177.1 - 1.4e-73 248.0 27.6 1.6e-73 247.8 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF79177.1 - 5e-16 58.3 30.5 5e-16 58.3 21.1 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF79179.1 - 8.3e-84 281.7 18.8 9.9e-84 281.4 13.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF79179.1 - 8.3e-36 123.4 43.3 2.1e-27 95.8 18.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EXF79179.1 - 9.8e-12 43.9 11.6 3.6e-08 32.2 1.2 2.5 2 0 0 2 2 2 2 MFS/sugar transport protein TRI12 PF06609.8 EXF79179.1 - 1.3e-05 23.6 7.6 4.3e-05 21.9 2.1 2.2 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Folate_carrier PF01770.13 EXF79179.1 - 0.0076 14.8 0.7 1.2 7.6 0.0 2.3 2 0 0 2 2 2 2 Reduced folate carrier Phage_holin_2 PF04550.7 EXF79179.1 - 0.021 14.8 0.1 0.061 13.4 0.0 1.7 1 0 0 1 1 1 0 Phage holin family 2 MFS_1_like PF12832.2 EXF79179.1 - 0.075 12.8 0.1 0.075 12.8 0.0 2.9 4 0 0 4 4 4 0 MFS_1 like family OATP PF03137.15 EXF79179.1 - 0.094 10.7 5.5 0.068 11.2 2.3 1.8 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family CTP_synth_N PF06418.9 EXF79180.1 - 1.4e-114 381.8 0.1 1.9e-114 381.4 0.1 1.1 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EXF79180.1 - 4.3e-50 169.8 0.0 6.5e-50 169.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EXF79180.1 - 0.00083 18.8 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase C26 CbiA PF01656.18 EXF79180.1 - 0.0026 17.2 0.0 0.0044 16.4 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ARID PF01388.16 EXF79181.1 - 3.1e-14 52.5 0.0 1.1e-13 50.8 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Img2 PF05046.9 EXF79182.1 - 2.5e-16 59.6 0.0 3.7e-16 59.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) SUI1 PF01253.17 EXF79182.1 - 0.0033 17.1 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor SUI1 Poly_export PF02563.11 EXF79182.1 - 0.064 13.0 0.0 0.61 9.8 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis/export protein eIF3_N PF09440.5 EXF79183.1 - 7.2e-44 149.1 0.3 1.9e-43 147.7 0.2 1.8 1 0 0 1 1 1 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EXF79183.1 - 3.3e-13 49.8 0.0 8.6e-13 48.5 0.0 1.8 1 0 0 1 1 1 1 PCI domain RPN7 PF10602.4 EXF79183.1 - 0.049 13.0 0.0 0.12 11.7 0.0 1.6 1 0 0 1 1 1 0 26S proteasome subunit RPN7 TPR_14 PF13428.1 EXF79183.1 - 0.26 12.0 2.2 20 6.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Mito_fiss_reg PF05308.6 EXF79183.1 - 0.89 8.8 7.8 2.8 7.2 4.0 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator Apc1 PF12859.2 EXF79184.1 - 4.2e-27 94.4 0.1 1.2e-26 92.9 0.1 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EXF79184.1 - 2.6e-05 24.1 2.5 0.052 13.8 0.2 4.6 4 0 0 4 4 4 2 Proteasome/cyclosome repeat Clathrin PF00637.15 EXF79185.1 - 7.6e-19 67.7 3.8 7.6e-19 67.7 2.7 2.4 2 1 0 2 2 2 1 Region in Clathrin and VPS WD40 PF00400.27 EXF79185.1 - 6.2e-07 29.0 0.5 0.001 18.8 0.2 4.0 3 1 0 3 3 3 1 WD domain, G-beta repeat Daxx PF03344.10 EXF79185.1 - 1.6e-05 23.6 15.0 1.6e-05 23.6 10.4 1.8 2 0 0 2 2 2 1 Daxx Family zf-RING_2 PF13639.1 EXF79185.1 - 5e-05 23.0 0.5 9.6e-05 22.1 0.3 1.5 1 0 0 1 1 1 1 Ring finger domain BUD22 PF09073.5 EXF79185.1 - 0.0002 20.5 11.6 0.0002 20.5 8.0 2.0 2 0 0 2 2 2 1 BUD22 zf-RING_5 PF14634.1 EXF79185.1 - 0.0036 17.0 3.6 0.0096 15.6 2.5 1.8 1 1 0 1 1 1 1 zinc-RING finger domain Vps39_1 PF10366.4 EXF79185.1 - 0.016 15.2 0.6 0.051 13.5 0.4 1.9 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 Tap-RNA_bind PF09162.5 EXF79185.1 - 0.2 11.2 0.1 0.42 10.2 0.1 1.4 1 0 0 1 1 1 0 Tap, RNA-binding CDC45 PF02724.9 EXF79185.1 - 0.26 9.2 21.3 0.0027 15.8 9.0 1.7 2 0 0 2 2 2 0 CDC45-like protein Pox_Ag35 PF03286.9 EXF79185.1 - 1 8.8 14.8 2.8 7.3 10.3 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SAPS PF04499.10 EXF79185.1 - 1.4 7.5 7.1 3.2 6.2 4.8 1.6 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein DNA_pol_phi PF04931.8 EXF79185.1 - 2.5 5.7 34.4 3.9 5.1 23.8 1.2 1 0 0 1 1 1 0 DNA polymerase phi Disaggr_assoc PF08480.5 EXF79186.1 - 0.038 13.4 0.2 0.046 13.1 0.1 1.1 1 0 0 1 1 1 0 Disaggregatase related DUF1180 PF06679.7 EXF79186.1 - 0.53 10.1 5.9 0.54 10.1 3.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1180) GatB_N PF02934.10 EXF79188.1 - 1.7e-103 345.4 0.0 2.9e-103 344.7 0.0 1.4 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EXF79188.1 - 7.3e-08 32.2 0.5 2.2e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 GatB domain DnaJ PF00226.26 EXF79189.1 - 2.2e-09 36.9 0.9 3.6e-08 33.0 0.7 2.5 2 0 0 2 2 2 1 DnaJ domain Pex14_N PF04695.8 EXF79189.1 - 0.048 13.7 7.0 0.3 11.1 0.1 2.8 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DEAD PF00270.24 EXF79190.1 - 2.1e-42 144.5 0.0 3e-42 143.9 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF79190.1 - 1.1e-23 82.8 0.1 2.2e-23 81.9 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain NACHT PF05729.7 EXF79191.1 - 1.8e-09 37.4 0.1 2e-05 24.2 0.0 4.1 3 1 0 3 3 3 2 NACHT domain AAA_16 PF13191.1 EXF79191.1 - 3.7e-07 30.3 10.9 0.00057 19.9 0.0 5.2 6 1 0 6 6 6 2 AAA ATPase domain AAA_22 PF13401.1 EXF79191.1 - 2e-05 24.7 0.2 0.017 15.2 0.0 4.6 5 0 0 5 5 5 1 AAA domain ABC_tran PF00005.22 EXF79191.1 - 0.011 16.0 0.0 0.088 13.1 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_10 PF12846.2 EXF79191.1 - 0.02 14.3 0.6 0.1 12.0 0.0 2.4 3 0 0 3 3 3 0 AAA-like domain RNA_helicase PF00910.17 EXF79191.1 - 0.074 13.2 0.0 0.28 11.3 0.0 2.1 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 EXF79191.1 - 0.093 12.2 0.1 0.21 11.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EXF79191.1 - 0.11 13.2 0.1 1.1 10.1 0.0 2.9 3 0 0 3 3 1 0 AAA domain AAA_PrkA PF08298.6 EXF79191.1 - 0.11 11.1 0.0 1.1 7.8 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain APS_kinase PF01583.15 EXF79191.1 - 0.12 12.0 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase Peptidase_M13 PF01431.16 EXF79191.1 - 0.22 10.6 0.0 2.2 7.4 0.0 2.1 2 0 0 2 2 2 0 Peptidase family M13 LrgB PF04172.11 EXF79193.1 - 2.2e-27 95.6 4.8 2.2e-27 95.6 3.3 3.0 3 0 0 3 3 3 1 LrgB-like family LrgA PF03788.9 EXF79193.1 - 0.28 10.9 20.6 0.047 13.3 7.2 3.9 3 1 1 4 4 4 0 LrgA family COesterase PF00135.23 EXF79194.1 - 6.7e-43 147.2 0.0 1e-42 146.5 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF79194.1 - 0.15 11.6 0.2 0.52 9.8 0.1 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold zf-C2H2_4 PF13894.1 EXF79195.1 - 3.7e-05 23.7 9.7 0.0015 18.7 0.9 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF79195.1 - 0.0012 19.0 13.3 0.019 15.2 1.9 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EXF79195.1 - 0.0083 16.3 3.0 0.0083 16.3 2.1 2.9 3 0 0 3 3 3 1 Zinc-finger double domain Integrin_B_tail PF07965.7 EXF79195.1 - 0.03 14.7 0.5 0.065 13.6 0.2 1.6 1 1 0 1 1 1 0 Integrin beta tail domain zf-met PF12874.2 EXF79195.1 - 0.031 14.4 5.6 0.42 10.8 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Zn_clus PF00172.13 EXF79196.1 - 3.9e-06 26.6 8.5 7.5e-06 25.7 5.9 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF79196.1 - 0.00022 20.2 0.2 0.0004 19.3 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aldo_ket_red PF00248.16 EXF79197.1 - 1.3e-70 237.5 0.0 1.5e-70 237.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Epimerase PF01370.16 EXF79198.1 - 1.4e-23 83.5 0.0 1.7e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EXF79198.1 - 5.1e-15 54.9 0.0 6.4e-15 54.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EXF79198.1 - 1.4e-09 38.2 0.1 1.9e-09 37.7 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EXF79198.1 - 2.4e-09 36.4 0.0 6.1e-05 22.0 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EXF79198.1 - 5.4e-07 28.7 0.0 8.5e-07 28.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EXF79198.1 - 8.6e-05 22.5 0.2 0.00034 20.5 0.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Ldh_1_N PF00056.18 EXF79198.1 - 0.0055 16.5 0.1 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain KR PF08659.5 EXF79198.1 - 0.01 15.5 0.1 0.022 14.4 0.0 1.7 1 1 0 1 1 1 0 KR domain NmrA PF05368.8 EXF79198.1 - 0.017 14.4 0.1 0.46 9.6 0.0 2.1 2 0 0 2 2 2 0 NmrA-like family Polysacc_synt_2 PF02719.10 EXF79198.1 - 0.061 12.2 0.0 0.2 10.5 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EXF79198.1 - 0.074 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DapB_N PF01113.15 EXF79198.1 - 0.094 12.6 0.0 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus FMN_dh PF01070.13 EXF79199.1 - 1.5e-114 382.6 0.0 1.9e-114 382.2 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EXF79199.1 - 9.6e-18 63.7 0.0 1.8e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EXF79199.1 - 0.00036 19.5 0.0 0.00077 18.4 0.0 1.4 2 0 0 2 2 2 1 Conserved region in glutamate synthase ThiG PF05690.9 EXF79199.1 - 0.0024 17.0 0.1 0.12 11.4 0.0 2.3 1 1 0 2 2 2 1 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 EXF79199.1 - 0.0053 15.6 0.0 0.014 14.2 0.0 1.6 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain DHDPS PF00701.17 EXF79200.1 - 5.3e-43 146.6 0.0 6.2e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DUF2196 PF09962.4 EXF79200.1 - 0.075 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2196) BNR_2 PF13088.1 EXF79201.1 - 2.2e-68 230.5 1.8 2.7e-68 230.2 1.3 1.0 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 EXF79201.1 - 1.1e-05 24.4 14.7 0.28 11.1 1.2 4.9 5 0 0 5 5 5 3 BNR/Asp-box repeat PSII_BNR PF14870.1 EXF79201.1 - 0.0018 17.3 0.6 0.069 12.1 0.0 2.8 3 0 0 3 3 3 1 Photosynthesis system II assembly factor YCF48 Glyco_hydro_43 PF04616.9 EXF79201.1 - 0.0037 16.4 0.0 0.0087 15.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 BNR_3 PF13859.1 EXF79201.1 - 0.0073 15.4 0.0 0.038 13.0 0.0 2.0 2 1 0 2 2 2 1 BNR repeat-like domain Sugar_tr PF00083.19 EXF79202.1 - 9.4e-89 298.0 18.6 1.1e-88 297.8 12.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF79202.1 - 6.7e-22 77.6 17.9 6.7e-22 77.6 12.4 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF791 PF05631.9 EXF79202.1 - 0.00023 19.9 2.1 0.0014 17.3 0.1 2.5 3 1 0 3 3 3 1 Protein of unknown function (DUF791) Aminotran_3 PF00202.16 EXF79204.1 - 7.2e-85 284.8 0.0 9.6e-85 284.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Fungal_trans_2 PF11951.3 EXF79204.1 - 4.3e-34 117.7 0.3 6.6e-34 117.1 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Pec_lyase_C PF00544.14 EXF79206.1 - 1.5e-43 148.6 3.0 2.2e-43 148.0 2.1 1.2 1 0 0 1 1 1 1 Pectate lyase MIP PF00230.15 EXF79207.1 - 3.6e-48 164.0 12.9 4.6e-48 163.6 9.0 1.1 1 0 0 1 1 1 1 Major intrinsic protein HPP PF04982.8 EXF79208.1 - 4.5e-38 129.7 5.2 4.5e-38 129.7 3.6 1.7 2 0 0 2 2 2 1 HPP family Ycf66_N PF07444.6 EXF79208.1 - 0.074 12.7 0.7 3.5 7.3 0.2 2.6 2 0 0 2 2 2 0 Ycf66 protein N-terminus Ion_trans_2 PF07885.11 EXF79208.1 - 0.08 12.6 2.5 0.22 11.2 0.0 2.5 2 0 0 2 2 2 0 Ion channel DUF2975 PF11188.3 EXF79208.1 - 3.5 7.3 7.3 16 5.1 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) adh_short PF00106.20 EXF79209.1 - 1.2e-15 57.8 0.5 2e-15 57.1 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF79209.1 - 2.3e-07 30.8 0.1 3.7e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF79209.1 - 3.1e-06 26.9 0.1 1.1e-05 25.2 0.0 1.8 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 EXF79209.1 - 0.00029 20.3 0.1 0.00057 19.3 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_PK PF05891.7 EXF79209.1 - 0.037 13.3 0.0 0.062 12.5 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Polysacc_synt_2 PF02719.10 EXF79209.1 - 0.037 12.9 0.1 0.1 11.4 0.0 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NrfD PF03916.9 EXF79210.1 - 0.043 13.2 4.7 0.075 12.4 3.3 1.3 1 0 0 1 1 1 0 Polysulphide reductase, NrfD p450 PF00067.17 EXF79211.1 - 3.7e-46 157.6 0.0 6.8e-46 156.7 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Peptidase_M28 PF04389.12 EXF79212.1 - 7.8e-16 58.3 0.0 1.5e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EXF79212.1 - 6.4e-07 29.0 0.3 4.3e-05 23.1 0.1 2.5 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 EXF79212.1 - 0.0095 15.4 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 AAA PF00004.24 EXF79213.1 - 5e-18 65.5 0.0 9.3e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EXF79213.1 - 2.6e-05 25.0 0.1 0.00047 20.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EXF79213.1 - 0.00048 20.4 0.1 0.018 15.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EXF79213.1 - 0.0016 18.4 0.1 0.0035 17.3 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EXF79213.1 - 0.002 18.2 0.0 0.011 15.8 0.0 2.1 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EXF79213.1 - 0.003 16.6 0.0 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EXF79213.1 - 0.021 14.5 0.2 0.06 13.1 0.2 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 EXF79213.1 - 0.033 13.9 0.1 0.092 12.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EXF79213.1 - 0.038 13.9 0.0 0.29 11.0 0.0 2.2 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.1 EXF79213.1 - 0.1 12.4 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain CBM_20 PF00686.14 EXF79214.1 - 1.4e-33 114.3 1.3 2.7e-33 113.4 0.9 1.5 1 0 0 1 1 1 1 Starch binding domain Chitin_bind_3 PF03067.10 EXF79214.1 - 9e-08 32.5 2.7 2.4e-05 24.6 0.0 2.8 2 1 0 3 3 3 2 Chitin binding domain Glyco_hydro_61 PF03443.9 EXF79214.1 - 0.0018 18.1 0.1 0.0079 16.0 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_25 PF03423.8 EXF79214.1 - 0.031 14.3 0.1 0.067 13.2 0.1 1.6 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) UL2 PF08196.6 EXF79215.1 - 0.79 9.5 6.3 0.41 10.4 2.0 2.4 2 1 0 2 2 2 0 UL2 protein DUF4083 PF13314.1 EXF79215.1 - 2.8 7.8 6.9 0.38 10.6 0.7 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) DUF373 PF04123.8 EXF79215.1 - 6.1 5.7 10.6 0.72 8.8 3.6 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF373) Abhydrolase_6 PF12697.2 EXF79216.1 - 4.1e-16 59.5 0.0 8e-16 58.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF79216.1 - 4.9e-07 29.5 0.0 1.2e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S8 PF00082.17 EXF79217.1 - 1.2e-53 182.0 0.0 2.3e-53 181.1 0.0 1.4 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EXF79217.1 - 4.4e-09 36.7 0.0 1.3e-08 35.1 0.0 1.9 1 1 0 1 1 1 1 Fn3-like domain (DUF1034) BNR_2 PF13088.1 EXF79218.1 - 6.6e-05 22.3 0.1 0.0044 16.3 0.0 2.4 1 1 0 2 2 2 2 BNR repeat-like domain BNR PF02012.15 EXF79218.1 - 0.0033 16.9 5.3 0.55 10.2 0.0 3.8 4 0 0 4 4 4 2 BNR/Asp-box repeat Glyco_hydro_35 PF01301.14 EXF79219.1 - 2.2e-87 293.3 0.7 3.1e-87 292.9 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.1 EXF79219.1 - 3.5e-54 181.8 7.3 1.9e-30 105.3 3.4 3.0 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom2 PF10435.4 EXF79219.1 - 3.8e-52 176.3 4.9 6.4e-52 175.5 3.4 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom3 PF13363.1 EXF79219.1 - 2.9e-20 71.4 0.1 1.8e-19 68.8 0.0 2.4 2 0 0 2 2 2 1 Beta-galactosidase, domain 3 Glyco_hydro_28 PF00295.12 EXF79220.1 - 1.1e-103 346.7 21.2 1.3e-103 346.4 14.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 MFS_1 PF07690.11 EXF79221.1 - 9.7e-23 80.4 43.4 1.1e-16 60.4 20.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily HSP70 PF00012.15 EXF79221.1 - 2.9e-13 48.6 0.2 5.1e-10 37.9 0.2 3.0 2 1 0 2 2 2 2 Hsp70 protein PUCC PF03209.10 EXF79221.1 - 3.2e-05 22.8 2.7 0.00033 19.5 1.3 2.4 2 0 0 2 2 2 1 PUCC protein Tropomyosin PF00261.15 EXF79222.1 - 0.0026 16.8 6.3 0.0044 16.1 4.4 1.3 1 0 0 1 1 1 1 Tropomyosin IncA PF04156.9 EXF79222.1 - 0.0028 17.2 1.5 0.021 14.4 0.5 2.1 1 1 1 2 2 2 1 IncA protein TPR_MLP1_2 PF07926.7 EXF79222.1 - 0.0067 16.1 4.2 0.012 15.3 2.9 1.4 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein CCDC144C PF14915.1 EXF79222.1 - 0.024 13.5 1.7 0.039 12.8 1.2 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Myosin_tail_1 PF01576.14 EXF79222.1 - 0.028 12.1 4.1 0.042 11.5 2.8 1.2 1 0 0 1 1 1 0 Myosin tail Herpes_BLRF2 PF05812.7 EXF79222.1 - 0.036 13.8 0.9 0.072 12.9 0.0 1.9 2 0 0 2 2 2 0 Herpesvirus BLRF2 protein V_ATPase_I PF01496.14 EXF79222.1 - 0.038 11.8 1.0 0.053 11.3 0.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cep57_CLD_2 PF14197.1 EXF79222.1 - 0.039 13.9 3.2 5.6 6.9 0.3 2.5 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Mnd1 PF03962.10 EXF79222.1 - 0.058 13.0 1.1 0.11 12.1 0.8 1.4 1 0 0 1 1 1 0 Mnd1 family DivIC PF04977.10 EXF79222.1 - 0.081 12.4 1.8 0.35 10.3 0.1 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF904 PF06005.7 EXF79222.1 - 0.36 11.1 4.8 13 6.1 3.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) DUF972 PF06156.8 EXF79222.1 - 0.57 10.5 3.3 2 8.8 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DUF4200 PF13863.1 EXF79222.1 - 0.59 10.0 6.5 2.7 7.9 4.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Lebercilin PF15619.1 EXF79222.1 - 8.3 5.7 9.8 2.4 7.5 3.9 2.2 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease IBR PF01485.16 EXF79223.1 - 1.1e-10 41.1 1.5 1.1e-10 41.1 1.0 4.4 3 2 0 3 3 3 2 IBR domain zf-C3HC4 PF00097.20 EXF79223.1 - 0.018 14.7 0.3 0.018 14.7 0.2 3.9 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DUF3133 PF11331.3 EXF79223.1 - 0.2 11.2 3.1 0.21 11.1 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3133) C1_4 PF07975.7 EXF79223.1 - 9.5 6.3 16.9 2.3 8.2 0.0 4.0 4 0 0 4 4 4 0 TFIIH C1-like domain ABC_membrane_2 PF06472.10 EXF79224.1 - 6.3e-109 363.4 0.9 6.3e-109 363.4 0.6 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EXF79224.1 - 1.2e-17 64.4 0.0 2.7e-17 63.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EXF79224.1 - 0.00049 20.1 0.0 0.0014 18.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EXF79224.1 - 0.0017 18.3 0.9 0.024 14.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EXF79224.1 - 0.036 13.5 0.0 0.084 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EXF79224.1 - 0.051 12.7 0.0 0.091 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EXF79224.1 - 0.054 13.8 0.1 0.23 11.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.14 EXF79224.1 - 0.078 12.1 0.0 0.22 10.6 0.0 1.7 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain zf-CSL PF05207.8 EXF79225.1 - 2.4e-26 90.9 1.4 3.1e-26 90.6 1.0 1.2 1 0 0 1 1 1 1 CSL zinc finger Zn-ribbon_8 PF09723.5 EXF79225.1 - 0.0077 16.1 0.5 0.013 15.4 0.3 1.5 1 0 0 1 1 1 1 Zinc ribbon domain Terminase_GpA PF05876.7 EXF79225.1 - 0.082 11.2 0.1 0.092 11.0 0.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) TF_Zn_Ribbon PF08271.7 EXF79225.1 - 0.17 11.1 1.6 0.38 10.1 1.1 1.7 1 1 0 1 1 1 0 TFIIB zinc-binding Prok-RING_1 PF14446.1 EXF79225.1 - 0.68 9.7 3.4 2.4 7.9 2.4 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 tRNA-synt_1 PF00133.17 EXF79227.1 - 1.6e-37 128.8 0.1 2.7e-27 95.0 0.0 3.3 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EXF79227.1 - 9.3e-17 60.7 0.0 8.2e-10 37.8 0.0 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EXF79227.1 - 1.5e-10 40.9 2.8 2e-10 40.6 1.2 1.8 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EXF79227.1 - 7.2e-08 31.9 0.0 1.6e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Clat_adaptor_s PF01217.15 EXF79229.1 - 9e-43 145.4 0.0 1.7e-42 144.4 0.0 1.4 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Frataxin_Cyay PF01491.11 EXF79230.1 - 2.6e-34 117.3 0.0 3.5e-34 116.8 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain AJAP1_PANP_C PF15298.1 EXF79231.1 - 0.013 15.3 0.1 0.02 14.7 0.1 1.3 1 0 0 1 1 1 0 AJAP1/PANP C-terminus DUF4381 PF14316.1 EXF79231.1 - 0.029 14.4 0.0 0.045 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) DUF4448 PF14610.1 EXF79231.1 - 0.13 11.7 0.0 0.21 11.0 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) Zn_clus PF00172.13 EXF79232.1 - 1.8e-08 34.1 9.3 3.5e-08 33.2 6.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF79232.1 - 0.00045 18.9 0.1 0.00077 18.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 EXF79233.1 - 1.3e-53 181.7 8.3 1.3e-53 181.7 5.7 1.9 2 0 0 2 2 2 1 RTA1 like protein DUF373 PF04123.8 EXF79233.1 - 0.47 9.4 8.3 0.51 9.3 4.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF373) Borrelia_P83 PF05262.6 EXF79234.1 - 0.0063 14.8 2.0 0.0062 14.8 1.4 1.2 1 0 0 1 1 1 1 Borrelia P83/100 protein SAPS PF04499.10 EXF79234.1 - 0.021 13.4 0.3 0.023 13.3 0.2 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Sporozoite_P67 PF05642.6 EXF79234.1 - 0.098 10.5 11.1 0.12 10.2 7.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ycf1 PF05758.7 EXF79234.1 - 0.15 9.7 0.2 0.13 9.9 0.1 1.1 1 0 0 1 1 1 0 Ycf1 Spore_II_R PF09551.5 EXF79234.1 - 0.48 10.4 4.4 0.75 9.8 3.1 1.2 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) POP1 PF06978.6 EXF79234.1 - 1.5 8.4 6.1 2.1 7.9 4.2 1.1 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 TraT PF05818.7 EXF79234.1 - 3.6 6.9 11.8 0.46 9.8 4.5 1.8 1 1 1 2 2 2 0 Enterobacterial TraT complement resistance protein Romo1 PF10247.4 EXF79234.1 - 5.1 7.3 0.0 5.1 7.3 0.0 2.7 1 1 1 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 5TM-5TMR_LYT PF07694.7 EXF79234.1 - 5.3 6.3 8.1 7.1 5.9 5.6 1.1 1 0 0 1 1 1 0 5TMR of 5TMR-LYT Gly-zipper_Omp PF13488.1 EXF79234.1 - 5.7 6.6 39.8 0.096 12.3 13.3 2.3 1 1 1 2 2 2 0 Glycine zipper Cu_bind_like PF02298.12 EXF79235.1 - 0.083 12.6 0.1 0.31 10.8 0.1 1.9 1 1 0 1 1 1 0 Plastocyanin-like domain Cas_csx3 PF09620.5 EXF79235.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_csx3) Glyco_hydro_43 PF04616.9 EXF79236.1 - 1.3e-53 181.9 7.8 1.1e-28 100.1 0.3 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 GST_N_3 PF13417.1 EXF79237.1 - 1.1e-24 86.4 0.0 2.4e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EXF79237.1 - 1.4e-15 57.0 0.1 5.2e-15 55.1 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EXF79237.1 - 3.4e-05 23.9 0.1 8.8e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EXF79237.1 - 0.00012 21.9 0.1 0.0002 21.1 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EXF79237.1 - 0.0046 16.9 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pro_dh PF01619.13 EXF79238.1 - 1.5e-36 126.0 0.0 2.2e-36 125.4 0.0 1.3 1 0 0 1 1 1 1 Proline dehydrogenase P5CR_dimer PF14748.1 EXF79239.1 - 5.1e-27 93.9 3.1 7.2e-27 93.5 0.6 2.3 2 1 1 3 3 3 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EXF79239.1 - 8.1e-16 58.2 0.5 1.6e-15 57.2 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EXF79239.1 - 3.6e-05 23.5 0.3 0.00011 22.0 0.1 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DUF4034 PF13226.1 EXF79240.1 - 0.14 11.1 0.4 9.6 5.2 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4034) Aldedh PF00171.17 EXF79241.1 - 7.5e-97 324.5 0.0 9.3e-97 324.2 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EXF79241.1 - 0.031 12.9 0.0 0.3 9.7 0.0 2.1 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) DAO PF01266.19 EXF79242.1 - 3e-41 141.5 0.0 4e-41 141.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF79242.1 - 3.3e-07 30.2 0.0 1.2e-06 28.4 0.0 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EXF79242.1 - 7.6e-06 26.1 0.0 0.0014 18.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF79242.1 - 0.00033 20.6 0.0 0.45 10.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF79242.1 - 0.002 17.9 0.1 0.17 11.6 0.0 2.3 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EXF79242.1 - 0.0029 16.5 0.0 0.59 8.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain GIDA PF01134.17 EXF79242.1 - 0.004 16.0 0.3 0.063 12.1 0.1 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EXF79242.1 - 0.0061 15.5 0.2 5.7 5.7 0.0 2.9 2 1 1 3 3 3 2 Lycopene cyclase protein HI0933_like PF03486.9 EXF79242.1 - 0.019 13.4 0.1 1.4 7.2 0.0 2.2 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.14 EXF79242.1 - 0.022 13.8 0.0 0.11 11.4 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.12 EXF79242.1 - 0.026 13.6 0.2 0.071 12.1 0.0 1.7 2 0 0 2 2 2 0 Thi4 family K_oxygenase PF13434.1 EXF79242.1 - 0.033 13.1 0.0 4.6 6.0 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) ThiF PF00899.16 EXF79242.1 - 0.049 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 ThiF family Shikimate_DH PF01488.15 EXF79242.1 - 0.13 12.3 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EXF79242.1 - 0.14 12.1 0.0 0.52 10.3 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Fungal_trans PF04082.13 EXF79243.1 - 3.4e-20 72.0 0.4 6.6e-20 71.0 0.2 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF79243.1 - 2.4e-06 27.3 13.6 2.4e-06 27.3 9.4 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aa_trans PF01490.13 EXF79244.1 - 2.4e-41 141.5 28.5 2.8e-41 141.3 19.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Pro_racemase PF05544.6 EXF79245.1 - 2.1e-125 417.8 0.1 2.4e-125 417.6 0.0 1.0 1 0 0 1 1 1 1 Proline racemase PhzC-PhzF PF02567.11 EXF79245.1 - 0.0037 16.5 0.0 0.0063 15.7 0.0 1.3 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein OCD_Mu_crystall PF02423.10 EXF79246.1 - 1.8e-17 63.0 0.1 5.7e-15 54.8 0.1 2.7 1 1 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EXF79246.1 - 6.4e-07 29.5 0.0 7.3e-06 26.1 0.0 2.5 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.17 EXF79246.1 - 0.071 13.6 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold p450 PF00067.17 EXF79247.1 - 1e-70 238.5 0.0 1.4e-70 238.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EXF79248.1 - 1.7e-34 118.8 0.0 2.5e-18 65.9 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF79248.1 - 4.1e-09 36.2 23.6 2.1e-08 33.9 6.7 2.6 3 0 0 3 3 3 2 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.19 EXF79249.1 - 1.5e-79 266.0 47.7 3e-42 144.1 17.3 3.5 4 0 0 4 4 3 2 ABC-2 type transporter PDR_CDR PF06422.7 EXF79249.1 - 4.4e-35 119.4 4.4 2.2e-32 110.7 0.0 3.3 3 0 0 3 3 3 2 CDR ABC transporter ABC_tran PF00005.22 EXF79249.1 - 3.2e-34 118.1 0.0 2.6e-16 60.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_trans_N PF14510.1 EXF79249.1 - 1.7e-19 69.7 0.0 3.8e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EXF79249.1 - 3.9e-06 26.1 11.9 3.9e-06 26.1 8.3 3.4 3 0 0 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.1 EXF79249.1 - 5.8e-06 25.8 0.0 0.001 18.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EXF79249.1 - 4.5e-05 23.3 0.7 0.023 14.5 0.0 3.4 3 0 0 3 3 3 1 AAA domain cobW PF02492.14 EXF79249.1 - 8.9e-05 22.0 1.1 0.0024 17.3 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 EXF79249.1 - 0.00028 20.1 0.0 0.033 13.3 0.0 3.1 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EXF79249.1 - 0.00033 19.8 0.1 0.011 14.9 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EXF79249.1 - 0.00061 19.8 0.1 0.083 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EXF79249.1 - 0.00086 18.7 2.4 0.026 14.0 0.2 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EXF79249.1 - 0.0023 18.2 0.1 0.14 12.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EXF79249.1 - 0.0023 17.9 0.1 1.2 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EXF79249.1 - 0.0028 17.8 1.1 1.7 8.7 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EXF79249.1 - 0.0041 17.9 0.0 0.6 10.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EXF79249.1 - 0.0047 16.6 1.5 2.4 7.9 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain AAA_28 PF13521.1 EXF79249.1 - 0.01 15.8 0.4 0.26 11.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EXF79249.1 - 0.016 14.1 0.2 1.2 7.9 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein PDR_assoc PF08370.6 EXF79249.1 - 0.026 14.0 9.1 0.34 10.4 0.5 3.6 3 0 0 3 3 3 0 Plant PDR ABC transporter associated AAA_23 PF13476.1 EXF79249.1 - 0.085 13.1 0.0 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EXF79249.1 - 0.19 10.7 0.5 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.24 EXF79249.1 - 0.21 11.8 0.1 14 5.8 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EXF79249.1 - 0.23 11.1 0.0 27 4.3 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase UPF0079 PF02367.12 EXF79249.1 - 0.62 9.7 2.7 1.2 8.8 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EXF79249.1 - 0.74 9.4 4.4 3.3 7.3 0.2 2.8 3 0 0 3 3 3 0 NACHT domain Bac_luciferase PF00296.15 EXF79250.1 - 1.3e-62 211.7 0.0 1.5e-62 211.4 0.0 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF2976 PF11190.3 EXF79251.1 - 0.26 10.8 2.9 0.51 9.9 1.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2976) GMC_oxred_N PF00732.14 EXF79252.1 - 1.8e-40 138.9 0.5 4.3e-22 78.6 0.0 2.2 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF79252.1 - 9e-39 133.0 0.0 1.4e-38 132.4 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EXF79252.1 - 0.00089 18.2 0.0 0.0092 14.9 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF79252.1 - 0.0043 16.9 0.0 0.0086 15.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF79252.1 - 0.012 15.5 0.4 0.03 14.3 0.2 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EXF79252.1 - 0.048 13.4 0.1 0.083 12.6 0.1 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EXF79252.1 - 0.068 12.0 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Zn_clus PF00172.13 EXF79253.1 - 0.015 15.2 0.2 0.024 14.5 0.2 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Pox_A_type_inc PF04508.7 EXF79253.1 - 0.12 12.1 0.2 0.53 10.1 0.4 1.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat AMP-binding PF00501.23 EXF79254.1 - 1.2e-174 580.5 0.0 3.4e-86 289.2 0.0 2.3 2 0 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.7 EXF79254.1 - 3.8e-41 140.6 0.0 7.2e-41 139.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Condensation PF00668.15 EXF79254.1 - 2.6e-38 131.6 0.0 4.5e-38 130.7 0.0 1.4 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 EXF79254.1 - 2.8e-17 62.7 0.4 2.9e-10 40.2 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site Epimerase PF01370.16 EXF79254.1 - 5.4e-09 35.8 0.0 1.4e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GFA PF04828.9 EXF79254.1 - 3e-06 27.0 0.0 8.7e-05 22.4 0.0 2.8 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme AMP-binding_C PF13193.1 EXF79254.1 - 1.9e-05 25.5 0.0 0.35 11.8 0.0 3.1 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain 3Beta_HSD PF01073.14 EXF79254.1 - 3.2e-05 22.7 0.1 0.00045 19.0 0.0 2.5 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EXF79254.1 - 0.017 15.1 0.3 0.43 10.5 0.0 2.8 2 0 0 2 2 2 0 NADH(P)-binding adh_short PF00106.20 EXF79254.1 - 0.051 13.4 1.3 0.13 12.1 0.2 2.3 2 0 0 2 2 2 0 short chain dehydrogenase Semialdhyde_dh PF01118.19 EXF79254.1 - 0.061 13.6 0.0 0.18 12.0 0.0 1.8 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EXF79254.1 - 0.18 11.7 0.0 0.46 10.4 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus UBA_2 PF08587.6 EXF79254.1 - 0.24 11.6 0.0 0.73 10.0 0.0 1.8 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) MFS_1 PF07690.11 EXF79255.1 - 2.3e-40 138.4 41.0 2.3e-40 138.4 28.4 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF79255.1 - 3.9e-10 38.8 25.6 5.3e-10 38.4 2.5 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EXF79255.1 - 1.9e-08 33.0 14.4 2.9e-08 32.4 10.0 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FAD_binding_4 PF01565.18 EXF79256.1 - 8e-18 64.2 0.0 1.6e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Cupin_2 PF07883.6 EXF79257.1 - 2.6e-05 23.6 0.1 4.3e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EXF79257.1 - 0.00066 19.1 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_6 PF12852.2 EXF79257.1 - 0.0044 16.6 0.0 0.0056 16.3 0.0 1.1 1 0 0 1 1 1 1 Cupin ARD PF03079.9 EXF79257.1 - 0.027 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 ARD/ARD' family DUF829 PF05705.9 EXF79258.1 - 5e-52 176.9 0.0 5.8e-52 176.7 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_6 PF12697.2 EXF79258.1 - 0.0055 16.6 0.0 0.01 15.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family 4HBT_3 PF13622.1 EXF79259.1 - 5.8e-44 150.7 0.1 6.7e-44 150.5 0.1 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Ala_racemase_N PF01168.15 EXF79260.1 - 2.2e-24 86.2 0.1 2.7e-24 85.9 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain D-ser_dehydrat PF14031.1 EXF79260.1 - 6.4e-21 74.3 0.0 1.4e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain GTP_CH_N PF12471.3 EXF79260.1 - 0.016 14.7 0.0 0.035 13.6 0.0 1.5 1 0 0 1 1 1 0 GTP cyclohydrolase N terminal UPF0081 PF03652.10 EXF79260.1 - 0.048 13.7 0.1 0.26 11.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0081) p450 PF00067.17 EXF79261.1 - 1.7e-48 165.2 0.0 2.2e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 D-ser_dehydrat PF14031.1 EXF79262.1 - 1.1e-26 92.8 0.0 1.9e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EXF79262.1 - 4e-15 55.9 0.0 5.5e-15 55.5 0.0 1.2 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Cpn10 PF00166.16 EXF79262.1 - 0.13 12.2 0.2 0.46 10.4 0.1 1.9 2 0 0 2 2 2 0 Chaperonin 10 Kd subunit Fungal_trans_2 PF11951.3 EXF79263.1 - 2.5e-42 144.8 5.5 3e-42 144.5 3.8 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF79263.1 - 2.1e-07 30.7 12.9 3.3e-07 30.0 8.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF605 PF04652.11 EXF79263.1 - 4.9 6.4 20.2 6.7 5.9 14.0 1.1 1 0 0 1 1 1 0 Vta1 like DNase_NucA_NucB PF14040.1 EXF79264.1 - 0.0026 17.8 2.2 0.011 15.9 0.1 2.7 2 1 0 2 2 2 1 Deoxyribonuclease NucA/NucB MGC-24 PF05283.6 EXF79266.1 - 0.00011 22.0 13.7 0.00021 21.1 9.5 1.5 1 0 0 1 1 1 1 Multi-glycosylated core protein 24 (MGC-24) Glycophorin_A PF01102.13 EXF79266.1 - 0.00047 19.9 1.0 0.00098 18.8 0.7 1.7 1 0 0 1 1 1 1 Glycophorin A TMEM154 PF15102.1 EXF79266.1 - 0.0024 17.6 0.1 0.0052 16.5 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family SKG6 PF08693.5 EXF79266.1 - 0.014 14.7 0.1 0.04 13.2 0.1 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rifin_STEVOR PF02009.11 EXF79266.1 - 0.063 12.9 0.6 0.082 12.5 0.4 1.3 1 1 0 1 1 1 0 Rifin/stevor family Bacteriocin_IIc PF10439.4 EXF79266.1 - 0.66 10.1 10.6 2.5 8.3 7.3 2.0 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF1633 PF07794.6 EXF79266.1 - 1.6 6.6 8.4 1.9 6.3 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) DDDD PF10161.4 EXF79267.1 - 0.58 9.8 2.0 2.1 8.0 0.1 2.6 3 0 0 3 3 3 0 Putative mitochondrial precursor protein DUF2236 PF09995.4 EXF79268.1 - 3.1e-30 105.2 0.2 4.5e-30 104.7 0.2 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) PsbR PF04725.7 EXF79268.1 - 0.018 15.0 0.1 1.5 8.8 0.0 2.7 2 0 0 2 2 2 0 Photosystem II 10 kDa polypeptide PsbR SNF2_N PF00176.18 EXF79270.1 - 1.3e-55 188.3 0.0 3.7e-55 186.8 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EXF79270.1 - 1.6e-09 37.5 0.0 4.5e-09 36.0 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EXF79270.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Methyltransf_17 PF12692.2 EXF79270.1 - 0.065 12.9 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-methionine methyltransferase NACHT PF05729.7 EXF79271.1 - 1e-05 25.2 0.0 4.3e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 NACHT domain AAA_22 PF13401.1 EXF79271.1 - 0.001 19.1 1.4 0.0062 16.6 0.0 3.0 4 1 0 4 4 4 1 AAA domain NB-ARC PF00931.17 EXF79271.1 - 0.0023 16.8 0.3 0.0087 14.9 0.0 2.2 3 0 0 3 3 3 1 NB-ARC domain AAA_19 PF13245.1 EXF79271.1 - 0.17 11.6 0.0 0.9 9.3 0.0 2.2 1 0 0 1 1 1 0 Part of AAA domain PALP PF00291.20 EXF79272.1 - 2e-62 211.1 1.1 2.5e-62 210.8 0.8 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DUF3453 PF11935.3 EXF79274.1 - 1.4e-71 240.7 0.1 1.9e-71 240.3 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) Sds3 PF08598.6 EXF79275.1 - 6.2e-17 61.8 8.7 6.2e-17 61.8 6.0 3.0 2 2 0 2 2 2 1 Sds3-like RRM_1 PF00076.17 EXF79276.1 - 4.7e-12 45.3 0.2 1.1e-07 31.3 0.0 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF79276.1 - 8.6e-10 38.4 0.0 7.4e-06 25.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF79276.1 - 2.1e-09 37.0 0.0 0.00013 21.7 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1977 PF09320.6 EXF79276.1 - 6.3 7.0 6.7 2.1 8.6 1.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1977) Tubulin PF00091.20 EXF79277.1 - 1.6e-62 211.1 0.0 2.2e-62 210.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EXF79277.1 - 3.7e-44 149.7 0.0 5.7e-44 149.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EXF79277.1 - 9e-05 22.0 0.0 0.00017 21.1 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain p450 PF00067.17 EXF79278.1 - 5.7e-39 133.9 0.0 8.1e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 3Beta_HSD PF01073.14 EXF79279.1 - 2.6e-22 78.8 0.0 3.7e-21 75.0 0.0 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EXF79279.1 - 2.4e-08 33.2 0.0 3.8e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EXF79279.1 - 1.7e-07 30.9 0.0 2.7e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF79279.1 - 8.1e-05 22.6 0.0 0.00085 19.3 0.0 2.5 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EXF79279.1 - 0.00019 21.4 0.1 0.00046 20.1 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF79279.1 - 0.11 12.2 0.8 0.19 11.3 0.6 1.5 1 1 0 1 1 1 0 KR domain Herpes_capsid PF06112.6 EXF79280.1 - 2.6 8.0 8.2 4.1 7.4 5.7 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Tme5_EGF_like PF09064.5 EXF79280.1 - 3.1 7.5 6.4 25 4.5 4.5 2.4 1 1 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like HTH_Tnp_Tc3_2 PF01498.13 EXF79282.1 - 4.9e-05 23.3 0.1 0.00019 21.4 0.0 2.0 2 0 0 2 2 2 1 Transposase HTH_32 PF13565.1 EXF79282.1 - 0.0042 17.8 7.2 0.0052 17.5 0.6 3.3 1 1 2 3 3 3 1 Homeodomain-like domain HTH_28 PF13518.1 EXF79282.1 - 0.031 14.2 0.2 0.079 12.9 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_23 PF13384.1 EXF79282.1 - 0.035 13.7 0.0 0.084 12.5 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_7 PF02796.10 EXF79282.1 - 0.05 13.4 0.8 30 4.5 0.1 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain of resolvase HTH_38 PF13936.1 EXF79282.1 - 0.06 12.9 0.0 0.16 11.5 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain RNA_pol_Rpo13 PF12136.3 EXF79282.1 - 1 9.1 4.8 2.2 8.0 2.9 1.8 1 1 0 1 1 1 0 RNA polymerase Rpo13 subunit HTH domain Cupin_2 PF07883.6 EXF79283.1 - 2.6e-07 30.0 0.0 4.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EXF79283.1 - 0.065 12.6 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF861) GFO_IDH_MocA PF01408.17 EXF79284.1 - 1.4e-11 44.9 0.0 3e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EXF79284.1 - 0.0019 17.9 0.0 0.0045 16.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain RNase_T PF00929.19 EXF79285.1 - 5.1e-26 91.8 0.0 6.2e-26 91.6 0.0 1.1 1 0 0 1 1 1 1 Exonuclease PGM_PMM_I PF02878.11 EXF79286.1 - 8.3e-33 112.7 0.0 1.2e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EXF79286.1 - 1.4e-24 86.3 0.0 3e-24 85.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EXF79286.1 - 7.8e-16 58.2 0.1 1.8e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EXF79286.1 - 1.7e-08 34.3 0.0 3.8e-08 33.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain HMG_box PF00505.14 EXF79288.1 - 7.4e-25 87.0 0.9 1.3e-24 86.2 0.6 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EXF79288.1 - 2.1e-18 66.4 1.1 2.1e-18 66.4 0.8 1.5 2 0 0 2 2 2 1 HMG-box domain HMG_box_5 PF14887.1 EXF79288.1 - 0.0024 17.6 1.0 0.0024 17.6 0.7 1.6 2 0 0 2 2 2 1 HMG (high mobility group) box 5 DUF1014 PF06244.7 EXF79288.1 - 0.028 14.6 1.7 0.061 13.5 0.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) CENP-H PF05837.7 EXF79289.1 - 1.6e-26 92.5 5.4 5e-26 90.9 0.7 2.2 2 0 0 2 2 2 1 Centromere protein H (CENP-H) TMF_TATA_bd PF12325.3 EXF79289.1 - 0.017 14.8 3.6 0.017 14.8 2.5 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DASH_Dad3 PF08656.5 EXF79289.1 - 0.081 12.6 2.0 0.11 12.2 0.0 2.1 2 1 0 2 2 2 0 DASH complex subunit Dad3 DUF972 PF06156.8 EXF79289.1 - 0.18 12.1 4.5 0.42 10.9 1.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 EXF79289.1 - 1.3 8.6 7.3 0.34 10.4 0.8 2.0 1 1 0 2 2 2 0 IncA protein DivIC PF04977.10 EXF79289.1 - 9.1 5.8 8.5 2.6 7.5 1.6 2.7 2 2 1 3 3 3 0 Septum formation initiator ATG11 PF10377.4 EXF79290.1 - 6.9e-41 139.1 0.1 6.9e-41 139.1 0.1 3.7 4 0 0 4 4 4 1 Autophagy-related protein 11 DUF3584 PF12128.3 EXF79290.1 - 0.00015 19.2 21.7 0.00015 19.2 15.0 4.5 1 1 2 4 4 4 2 Protein of unknown function (DUF3584) ERM PF00769.14 EXF79290.1 - 0.00041 19.9 22.1 0.00041 19.9 15.3 7.1 3 1 3 6 6 6 1 Ezrin/radixin/moesin family Cleaved_Adhesin PF07675.6 EXF79290.1 - 0.00052 19.6 0.0 0.0014 18.2 0.0 1.7 1 0 0 1 1 1 1 Cleaved Adhesin Domain Atg14 PF10186.4 EXF79290.1 - 0.00094 18.2 11.3 0.00094 18.2 7.9 6.2 2 1 4 6 6 6 2 UV radiation resistance protein and autophagy-related subunit 14 TPR_MLP1_2 PF07926.7 EXF79290.1 - 0.0038 16.9 14.2 0.0038 16.9 9.9 8.7 5 3 1 7 7 7 1 TPR/MLP1/MLP2-like protein TMF_DNA_bd PF12329.3 EXF79290.1 - 0.0078 16.0 4.4 0.0078 16.0 3.1 10.1 6 2 5 11 11 11 1 TATA element modulatory factor 1 DNA binding B5 PF03484.10 EXF79290.1 - 0.011 15.5 0.6 0.51 10.1 0.0 2.9 2 0 0 2 2 2 0 tRNA synthetase B5 domain Nop14 PF04147.7 EXF79291.1 - 0.00075 17.5 8.0 0.0011 16.9 5.5 1.2 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 EXF79291.1 - 0.13 10.2 6.6 0.2 9.6 4.6 1.2 1 0 0 1 1 1 0 CDC45-like protein NOA36 PF06524.7 EXF79291.1 - 3.3 6.8 10.7 5.6 6.1 7.4 1.3 1 0 0 1 1 1 0 NOA36 protein SDF PF00375.13 EXF79292.1 - 1.4e-91 307.1 32.5 1.7e-91 306.8 22.5 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family Dynamin_N PF00350.18 EXF79293.1 - 1.1e-30 106.6 0.0 1.9e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EXF79293.1 - 7.7e-16 57.7 1.0 4.2e-14 52.0 0.1 2.4 3 0 0 3 3 3 2 Dynamin central region MMR_HSR1 PF01926.18 EXF79293.1 - 0.0007 19.5 0.0 0.0039 17.1 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EXF79293.1 - 0.049 14.1 0.0 0.19 12.1 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein FeoB_N PF02421.13 EXF79293.1 - 0.15 11.2 0.1 2.8 7.1 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B ABC2_membrane PF01061.19 EXF79295.1 - 6.9e-77 257.3 63.5 8e-41 139.5 18.9 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EXF79295.1 - 4.5e-36 124.1 0.0 1.6e-17 64.0 0.0 2.7 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 EXF79295.1 - 1.1e-33 114.9 1.3 1e-27 95.8 0.0 3.8 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.1 EXF79295.1 - 2.9e-17 62.5 0.0 7e-17 61.3 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EXF79295.1 - 7e-14 51.6 37.1 1.5e-09 37.3 10.3 2.5 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.1 EXF79295.1 - 5.4e-06 25.9 0.1 0.0029 17.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EXF79295.1 - 2.3e-05 23.6 0.1 0.001 18.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 EXF79295.1 - 9.4e-05 22.3 0.2 0.12 12.2 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EXF79295.1 - 0.00014 21.9 2.1 0.14 12.1 0.1 2.8 3 0 0 3 3 2 2 AAA ATPase domain cobW PF02492.14 EXF79295.1 - 0.00021 20.8 0.5 0.19 11.1 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.1 EXF79295.1 - 0.00063 20.0 0.1 0.17 12.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EXF79295.1 - 0.00089 18.5 0.0 0.24 10.6 0.0 3.2 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA PF00004.24 EXF79295.1 - 0.0012 19.0 0.3 0.18 11.9 0.1 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EXF79295.1 - 0.0021 18.1 0.6 2.3 8.3 0.1 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EXF79295.1 - 0.0045 16.4 0.6 0.25 10.8 0.2 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 EXF79295.1 - 0.012 15.3 0.4 6.6 6.3 0.0 2.8 2 0 0 2 2 2 0 NACHT domain AAA_19 PF13245.1 EXF79295.1 - 0.012 15.3 1.1 0.85 9.4 0.1 2.5 2 0 0 2 2 2 0 Part of AAA domain AAA_21 PF13304.1 EXF79295.1 - 0.023 14.6 0.6 2.8 7.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_17 PF13207.1 EXF79295.1 - 0.03 15.1 0.0 3.4 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EXF79295.1 - 0.034 14.0 0.8 6.5 6.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EXF79295.1 - 0.039 13.6 0.0 0.97 9.0 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase AAA_30 PF13604.1 EXF79295.1 - 0.071 12.6 0.1 12 5.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EXF79295.1 - 0.091 12.1 1.4 31 3.8 0.0 3.7 4 0 0 4 4 4 0 AAA-like domain UPF0079 PF02367.12 EXF79295.1 - 0.14 11.8 0.4 8.5 6.0 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SRP-alpha_N PF04086.8 EXF79296.1 - 0.0022 17.4 11.9 0.0033 16.8 8.2 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal Afi1 PF07792.7 EXF79296.1 - 0.49 10.3 4.5 29 4.6 3.6 2.2 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Amidohydro_2 PF04909.9 EXF79297.1 - 2e-12 47.2 0.0 6.5e-08 32.4 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase Aldo_ket_red PF00248.16 EXF79298.1 - 3.5e-69 232.7 0.1 4e-69 232.5 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Trypsin PF00089.21 EXF79301.1 - 4.4e-08 32.9 0.0 6.6e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Trypsin Polysacc_deac_1 PF01522.16 EXF79302.1 - 5.4e-25 87.4 0.0 1e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EXF79302.1 - 0.032 13.6 0.0 0.056 12.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF937 PF06078.6 EXF79302.1 - 0.045 13.9 0.4 0.095 12.9 0.1 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF937) MGC-24 PF05283.6 EXF79302.1 - 2 8.1 18.3 4.2 7.1 12.7 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Phyto_Pns9_10 PF05878.6 EXF79302.1 - 4.8 6.1 7.1 2.3 7.1 0.0 2.1 2 0 0 2 2 2 0 Phytoreovirus nonstructural protein Pns9/Pns10 Git3 PF11710.3 EXF79305.1 - 6e-21 74.9 10.2 1.6e-20 73.5 7.1 1.7 1 1 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 EXF79305.1 - 3.2e-10 39.6 4.2 5.7e-10 38.7 2.9 1.4 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 EXF79305.1 - 0.0015 18.2 0.4 0.0051 16.5 0.3 1.8 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 C-term Dicty_CAR PF05462.6 EXF79305.1 - 0.0091 14.9 9.4 0.018 13.9 6.5 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor FixP_N PF14715.1 EXF79305.1 - 6.7 6.1 11.3 6.7 6.1 0.8 3.0 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP ECH PF00378.15 EXF79309.1 - 2.2e-21 76.1 0.1 6.6e-17 61.4 0.1 2.2 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family Acetyltransf_1 PF00583.19 EXF79310.1 - 4.5e-07 29.8 0.0 7.7e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF79310.1 - 9.9e-05 22.4 0.0 0.00024 21.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EXF79310.1 - 0.00051 19.9 0.0 0.0013 18.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EXF79310.1 - 0.0015 18.6 0.0 0.0081 16.2 0.0 2.2 1 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Lipase_GDSL PF00657.17 EXF79311.1 - 6.3e-10 39.2 0.0 7e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase AAA PF00004.24 EXF79312.1 - 4e-16 59.4 0.0 1.9e-15 57.2 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EXF79312.1 - 0.00073 19.2 0.0 0.0047 16.6 0.0 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Zot PF05707.7 EXF79312.1 - 0.0048 16.3 0.0 0.044 13.2 0.0 2.3 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) DUF1233 PF06806.7 EXF79312.1 - 0.0055 16.2 0.0 0.017 14.6 0.0 1.8 2 0 0 2 2 2 1 Putative excisionase (DUF1233) AAA_18 PF13238.1 EXF79312.1 - 0.0055 16.9 0.0 0.022 15.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EXF79312.1 - 0.0067 16.4 0.0 0.018 15.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EXF79312.1 - 0.014 16.1 0.1 0.096 13.5 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EXF79312.1 - 0.018 15.1 0.0 0.068 13.3 0.0 1.9 1 1 0 1 1 1 0 AAA domain CPT PF07931.7 EXF79312.1 - 0.081 12.5 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_24 PF13479.1 EXF79312.1 - 0.1 12.1 0.0 0.25 10.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain Sugar_tr PF00083.19 EXF79313.1 - 7.8e-110 367.5 23.8 1e-109 367.1 16.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF79313.1 - 3.3e-26 91.8 32.6 5.3e-19 68.1 6.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Lysis_S PF04971.7 EXF79313.1 - 0.028 14.1 2.4 0.045 13.4 0.3 2.4 2 0 0 2 2 2 0 Lysis protein S Lipase_GDSL_2 PF13472.1 EXF79314.1 - 1.8e-12 47.7 0.1 2.6e-12 47.2 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EXF79314.1 - 8.1e-06 25.8 0.0 1.4e-05 25.0 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_3 PF14606.1 EXF79314.1 - 0.013 15.2 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family RTA1 PF04479.8 EXF79315.1 - 1.6e-37 129.1 2.3 2e-37 128.8 1.6 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF2244 PF10003.4 EXF79315.1 - 6.5 6.1 11.3 0.11 11.8 0.6 2.6 3 0 0 3 3 3 0 Integral membrane protein (DUF2244) GST_N_3 PF13417.1 EXF79316.1 - 5.9e-11 42.4 0.0 1.1e-10 41.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EXF79316.1 - 2.5e-07 30.5 0.0 4.4e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EXF79316.1 - 4.6e-07 29.7 0.0 7.4e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EXF79316.1 - 0.00022 21.6 0.0 0.00044 20.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EXF79316.1 - 0.00099 19.0 0.1 0.0021 17.9 0.1 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Epimerase PF01370.16 EXF79317.1 - 0.00029 20.3 0.0 0.00054 19.4 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EXF79317.1 - 0.0076 15.2 0.0 0.013 14.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EXF79317.1 - 0.0085 16.1 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EXF79317.1 - 0.011 14.9 0.0 0.016 14.4 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.12 EXF79317.1 - 0.022 13.6 0.1 4.7 6.0 0.1 2.6 2 1 0 2 2 2 0 RmlD substrate binding domain 3Beta_HSD PF01073.14 EXF79317.1 - 0.17 10.5 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Peptidase_M35 PF02102.10 EXF79318.1 - 6.1e-81 271.8 20.6 7.4e-81 271.5 14.3 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EXF79318.1 - 0.00023 21.6 2.8 0.0004 20.9 1.6 1.6 1 1 0 1 1 1 1 Lysine-specific metallo-endopeptidase DUF4397 PF14344.1 EXF79318.1 - 0.31 11.3 3.4 0.52 10.6 0.8 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4397) Zn_clus PF00172.13 EXF79319.1 - 2.1e-08 33.8 8.9 4e-08 33.0 6.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF79319.1 - 6.4e-08 31.5 1.9 6.3e-07 28.3 0.1 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Pox_F17 PF04767.7 EXF79319.1 - 1.7 8.9 5.0 4.3 7.6 3.5 1.6 1 0 0 1 1 1 0 DNA-binding 11 kDa phosphoprotein Peptidase_M28 PF04389.12 EXF79320.1 - 2.4e-32 112.0 0.0 3.9e-32 111.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EXF79320.1 - 1.1e-11 44.3 0.2 2.1e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EXF79320.1 - 1.3e-05 24.7 0.0 2.4e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 HET PF06985.6 EXF79321.1 - 8.4e-25 87.5 1.1 6.4e-24 84.6 0.8 2.3 2 1 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Beta-lactamase PF00144.19 EXF79322.1 - 3.3e-47 161.1 0.0 4.1e-47 160.8 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Methyltransf_23 PF13489.1 EXF79323.1 - 4e-19 68.8 0.0 6e-19 68.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF79323.1 - 1.1e-12 47.7 0.0 7.5e-12 45.0 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF79323.1 - 6.3e-10 39.6 0.0 9.4e-09 35.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF79323.1 - 1.6e-09 38.1 0.0 7e-09 36.0 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF79323.1 - 4.3e-07 30.3 0.0 9.3e-06 26.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF79323.1 - 0.00097 19.4 0.0 0.002 18.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF79323.1 - 0.001 18.1 0.0 0.0032 16.5 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 EXF79323.1 - 0.003 17.5 0.0 0.0068 16.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF79323.1 - 0.0044 16.4 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EXF79323.1 - 0.0054 15.9 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EXF79323.1 - 0.013 15.4 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EXF79323.1 - 0.017 14.5 0.0 0.029 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MFS_1 PF07690.11 EXF79324.1 - 7.2e-25 87.4 33.7 1.9e-24 86.0 20.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EXF79324.1 - 0.00026 20.6 0.4 0.0011 18.7 0.2 2.1 2 0 0 2 2 2 1 MFS_1 like family DUF843 PF05814.6 EXF79324.1 - 0.14 11.9 0.3 0.32 10.7 0.2 1.6 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) SBP_bac_5 PF00496.17 EXF79325.1 - 1.4e-44 152.4 0.0 1.7e-44 152.1 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle FGE-sulfatase PF03781.11 EXF79326.1 - 3e-41 141.4 1.1 4e-41 141.0 0.8 1.1 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 AAA_22 PF13401.1 EXF79326.1 - 2.8e-06 27.5 0.3 1.9e-05 24.7 0.2 2.2 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EXF79326.1 - 2.5e-05 23.9 0.1 6.8e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_23 PF13476.1 EXF79326.1 - 2.7e-05 24.6 0.0 3.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EXF79326.1 - 5.8e-05 23.1 1.2 0.028 14.4 0.8 2.5 1 1 0 1 1 1 1 AAA ATPase domain DUF953 PF06110.6 EXF79326.1 - 8.2e-05 22.0 0.0 0.0002 20.8 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) AAA_5 PF07728.9 EXF79326.1 - 0.00016 21.4 0.1 0.0026 17.4 0.1 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EXF79326.1 - 0.00032 20.3 0.0 0.00097 18.8 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EXF79326.1 - 0.00032 20.1 0.0 0.00062 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activ_2 PF14532.1 EXF79326.1 - 0.0004 20.4 0.0 0.0012 18.8 0.0 1.8 1 1 1 2 2 1 1 Sigma-54 interaction domain AAA_17 PF13207.1 EXF79326.1 - 0.002 18.9 0.0 0.0048 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EXF79326.1 - 0.0044 16.9 0.0 0.011 15.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EXF79326.1 - 0.0048 16.4 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.14 EXF79326.1 - 0.0071 15.5 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain Arch_ATPase PF01637.13 EXF79326.1 - 0.0082 15.8 0.0 0.021 14.5 0.0 1.6 1 1 0 1 1 1 1 Archaeal ATPase Rad17 PF03215.10 EXF79326.1 - 0.0082 14.8 0.0 0.011 14.4 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_33 PF13671.1 EXF79326.1 - 0.0086 15.9 0.0 0.018 14.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EXF79326.1 - 0.014 14.9 0.0 0.087 12.4 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 EXF79326.1 - 0.016 14.6 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein PhoH PF02562.11 EXF79326.1 - 0.018 14.2 0.0 0.1 11.8 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA PF00004.24 EXF79326.1 - 0.022 14.9 0.0 0.037 14.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EXF79326.1 - 0.035 12.9 0.0 0.057 12.3 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein RNA_helicase PF00910.17 EXF79326.1 - 0.035 14.2 0.0 0.065 13.4 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ABC_tran PF00005.22 EXF79326.1 - 0.04 14.2 0.0 0.079 13.2 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA_10 PF12846.2 EXF79326.1 - 0.072 12.5 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain KaiC PF06745.8 EXF79326.1 - 0.091 11.8 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 KaiC AAA_21 PF13304.1 EXF79326.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EXF79326.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase CbiA PF01656.18 EXF79326.1 - 0.19 11.1 0.1 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.10 EXF79326.1 - 0.19 11.4 0.0 0.33 10.6 0.0 1.3 1 0 0 1 1 1 0 NTPase SRP54 PF00448.17 EXF79326.1 - 0.29 10.5 0.0 0.46 9.8 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Fungal_trans PF04082.13 EXF79328.1 - 1.2e-07 30.8 0.3 3.6e-07 29.3 0.0 2.0 3 0 0 3 3 3 1 Fungal specific transcription factor domain DUF1593 PF07632.6 EXF79329.1 - 9.9e-81 270.8 0.0 1.3e-80 270.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.10 EXF79329.1 - 6.9e-05 21.3 0.0 9.8e-05 20.8 0.0 1.2 1 0 0 1 1 1 1 REJ domain NAD_binding_1 PF00175.16 EXF79332.1 - 2.7e-27 95.4 0.0 9.3e-27 93.7 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EXF79332.1 - 3.3e-13 49.6 0.0 5.6e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EXF79332.1 - 1.4e-06 28.2 0.2 0.002 18.0 0.0 2.6 2 1 1 3 3 3 2 Ferric reductase NAD binding domain VPS9 PF02204.13 EXF79334.1 - 1.8e-17 63.2 0.1 3.6e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Ank_5 PF13857.1 EXF79334.1 - 3.7e-15 55.6 0.3 6.4e-10 38.9 0.0 4.9 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EXF79334.1 - 3.9e-12 46.3 0.0 7.1e-08 32.6 0.0 3.7 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EXF79334.1 - 3.3e-11 43.3 0.5 0.0063 16.9 0.0 5.6 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF79334.1 - 9.9e-09 34.6 0.3 0.14 12.5 0.0 5.9 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.25 EXF79334.1 - 1.4e-07 30.9 1.0 0.0091 15.7 0.0 4.7 6 0 0 6 6 6 2 Ankyrin repeat PX PF00787.19 EXF79334.1 - 0.03 14.1 0.0 0.14 12.0 0.0 2.2 2 0 0 2 2 2 0 PX domain Sugar_tr PF00083.19 EXF79336.1 - 7.6e-73 245.6 31.2 9.2e-73 245.3 21.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF79336.1 - 7.4e-27 93.9 57.6 2.3e-24 85.7 25.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Mem_trans PF03547.13 EXF79336.1 - 0.0014 16.9 4.2 0.0014 16.9 2.9 2.9 3 1 1 4 4 4 1 Membrane transport protein MFS_1_like PF12832.2 EXF79336.1 - 0.003 17.2 2.2 0.16 11.7 0.3 2.9 2 0 0 2 2 2 1 MFS_1 like family Fungal_trans_2 PF11951.3 EXF79337.1 - 4e-11 42.1 4.6 3.5e-10 39.0 3.2 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain EGF_2 PF07974.8 EXF79338.1 - 0.00042 20.4 11.4 0.00079 19.5 7.9 1.5 1 0 0 1 1 1 1 EGF-like domain EB PF01683.13 EXF79338.1 - 1.1 9.3 8.8 2.3 8.3 6.1 1.4 1 0 0 1 1 1 0 EB module NPP1 PF05630.6 EXF79339.1 - 3.6e-69 232.6 0.1 4.2e-69 232.4 0.1 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) MFS_1 PF07690.11 EXF79340.1 - 1.9e-15 56.4 22.5 2e-14 53.1 11.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 EXF79340.1 - 1.3e-07 31.2 1.8 4.5e-07 29.5 1.2 1.9 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Hydrophobin_2 PF06766.6 EXF79341.1 - 1.4e-10 40.7 10.0 1.9e-10 40.2 6.9 1.2 1 0 0 1 1 1 1 Fungal hydrophobin Hydrophobin PF01185.13 EXF79341.1 - 0.031 14.7 0.2 0.031 14.7 0.2 2.0 2 0 0 2 2 2 0 Fungal hydrophobin adh_short PF00106.20 EXF79343.1 - 8.7e-24 84.3 0.1 1.2e-23 83.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF79343.1 - 5.2e-15 55.5 0.1 9.8e-15 54.6 0.1 1.4 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF79343.1 - 4.4e-11 42.9 0.2 6.2e-11 42.5 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EXF79343.1 - 0.00013 21.4 0.1 0.00029 20.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EXF79343.1 - 0.1 12.6 0.1 0.2 11.7 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EXF79343.1 - 0.11 11.3 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NEMO PF11577.3 EXF79344.1 - 0.049 13.4 0.3 0.15 11.8 0.2 1.8 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO bZIP_1 PF00170.16 EXF79344.1 - 0.08 12.9 5.2 0.17 11.8 3.6 1.6 1 0 0 1 1 1 0 bZIP transcription factor DUF2312 PF10073.4 EXF79344.1 - 0.14 11.4 1.1 0.29 10.5 0.8 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) DivIC PF04977.10 EXF79344.1 - 0.66 9.4 3.2 0.95 8.9 0.9 2.0 2 0 0 2 2 2 0 Septum formation initiator bZIP_Maf PF03131.12 EXF79344.1 - 9.1 6.6 11.0 23 5.3 4.5 2.5 2 0 0 2 2 2 0 bZIP Maf transcription factor UDPGT PF00201.13 EXF79346.1 - 1.8e-14 53.1 0.0 4.6e-12 45.2 0.0 2.1 2 0 0 2 2 2 2 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_transf_28 PF03033.15 EXF79346.1 - 1.3e-06 28.2 0.3 4.4e-06 26.4 0.1 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain AcetylCoA_hydro PF02550.10 EXF79347.1 - 1e-49 169.0 0.0 1.6e-49 168.4 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain AcetylCoA_hyd_C PF13336.1 EXF79347.1 - 2.4e-41 140.9 0.0 3.6e-41 140.3 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain Bac_luciferase PF00296.15 EXF79348.1 - 9.7e-62 208.8 1.1 1.6e-61 208.1 0.8 1.3 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.11 EXF79349.1 - 2.1e-08 33.2 34.9 2.1e-08 33.2 24.2 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EXF79349.1 - 5e-06 26.1 3.4 5e-06 26.1 2.4 2.8 3 0 0 3 3 3 2 Ion channel regulatory protein UNC-93 Pyr_redox_3 PF13738.1 EXF79350.1 - 7.9e-20 71.7 0.0 1.4e-19 70.9 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EXF79350.1 - 3.6e-12 45.2 0.0 1.4e-10 40.0 0.0 2.4 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EXF79350.1 - 4.2e-09 36.3 0.0 1.5e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EXF79350.1 - 2e-05 23.6 0.0 0.0011 17.9 0.0 2.7 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EXF79350.1 - 0.00016 21.5 0.5 0.12 12.1 0.0 3.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EXF79350.1 - 0.011 14.6 0.0 0.87 8.4 0.0 2.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF79350.1 - 0.013 15.3 0.0 0.058 13.2 0.0 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF79350.1 - 0.013 14.5 0.0 0.064 12.3 0.0 1.9 2 0 0 2 2 2 0 Thi4 family OmdA PF13376.1 EXF79350.1 - 0.12 12.0 0.7 4.2 7.1 0.0 2.8 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated Pyr_redox PF00070.22 EXF79350.1 - 0.14 12.6 0.2 21 5.5 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF79350.1 - 0.28 9.6 0.5 4 5.8 0.3 2.2 2 0 0 2 2 2 0 HI0933-like protein MFS_1 PF07690.11 EXF79351.1 - 6.7e-28 97.4 29.7 9.9e-28 96.8 20.6 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Bac_luciferase PF00296.15 EXF79352.1 - 1.2e-62 211.8 0.1 1.5e-62 211.4 0.1 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase Glyco_hydro_12 PF01670.11 EXF79353.1 - 1.3e-33 115.9 0.9 1.3e-33 115.9 0.6 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 12 Rotavirus_VP1 PF12289.3 EXF79353.1 - 0.12 11.9 0.0 0.56 9.8 0.0 2.0 2 0 0 2 2 2 0 Rotavirus VP1 structural protein Phage_holin_5 PF06946.6 EXF79353.1 - 1.1 9.5 8.3 0.25 11.5 1.0 2.6 1 1 1 2 2 2 0 Phage holin Fungal_trans PF04082.13 EXF79354.1 - 7.5e-15 54.5 1.5 1.1e-14 53.9 1.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF79354.1 - 9.9e-09 34.9 10.9 2.4e-08 33.7 7.5 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD_binding_3 PF01494.14 EXF79355.1 - 2.4e-16 59.7 0.0 7.5e-16 58.1 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EXF79355.1 - 0.00074 19.4 0.1 0.0018 18.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 EXF79355.1 - 0.0014 18.6 0.0 0.0036 17.2 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain DAO PF01266.19 EXF79355.1 - 0.0018 17.2 0.0 0.004 16.1 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EXF79355.1 - 0.0035 16.4 0.0 0.0057 15.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_Gly3P_dh_N PF01210.18 EXF79355.1 - 0.087 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EXF79355.1 - 0.09 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox_2 PF07992.9 EXF79355.1 - 0.12 12.1 0.0 0.28 11.0 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SseC PF04888.7 EXF79357.1 - 0.56 9.4 10.4 1 8.6 7.2 1.4 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Glyco_hydro_61 PF03443.9 EXF79358.1 - 1.3e-05 25.0 0.0 2.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Chitin_bind_3 PF03067.10 EXF79358.1 - 6.8e-05 23.2 0.0 9.9e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Chitin binding domain AATase PF07247.7 EXF79359.1 - 0.15 10.5 0.1 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 Alcohol acetyltransferase BTB PF00651.26 EXF79361.1 - 3.5e-05 23.7 0.0 6.7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain ADH_N PF08240.7 EXF79362.1 - 0.017 14.9 0.0 0.035 13.8 0.0 1.6 1 1 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain F-box PF00646.28 EXF79363.1 - 0.02 14.5 3.8 0.16 11.6 2.6 2.5 1 1 0 1 1 1 0 F-box domain UCH PF00443.24 EXF79364.1 - 1.9e-41 141.9 0.1 1.7e-35 122.4 0.0 2.8 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EXF79364.1 - 8.4e-13 48.4 4.5 2.1e-11 43.8 2.0 3.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Oxysterol_BP PF01237.13 EXF79365.1 - 4.5e-91 304.9 0.0 5.3e-91 304.7 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein Fringe PF02434.11 EXF79366.1 - 1.7e-08 34.0 0.4 2.8e-07 30.0 0.3 2.0 1 1 0 1 1 1 1 Fringe-like PAN_1 PF00024.21 EXF79366.1 - 0.002 17.8 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.1 EXF79366.1 - 0.019 14.6 0.3 0.035 13.8 0.2 1.4 1 0 0 1 1 1 0 PAN domain Galactosyl_T PF01762.16 EXF79366.1 - 0.052 13.1 0.1 0.17 11.4 0.0 1.8 1 1 1 2 2 2 0 Galactosyltransferase DUF4305 PF14146.1 EXF79367.1 - 0.1 12.3 0.8 0.1 12.3 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4305) BCS1_N PF08740.6 EXF79368.1 - 1.5e-44 151.8 0.0 2.1e-44 151.4 0.0 1.2 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EXF79368.1 - 1.7e-16 60.5 0.0 2.9e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EXF79368.1 - 4.7e-05 22.8 0.0 0.00044 19.7 0.0 2.3 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 EXF79368.1 - 6.6e-05 23.7 0.0 0.00014 22.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EXF79368.1 - 0.0012 18.5 0.0 0.0026 17.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EXF79368.1 - 0.0023 17.8 0.0 0.0045 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EXF79368.1 - 0.0052 16.9 0.0 0.01 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EXF79368.1 - 0.0075 15.3 0.0 0.015 14.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EXF79368.1 - 0.0092 15.9 0.0 0.061 13.3 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 EXF79368.1 - 0.02 13.8 0.0 0.043 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_29 PF13555.1 EXF79368.1 - 0.021 14.3 0.0 0.046 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EXF79368.1 - 0.027 14.7 0.0 0.047 13.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AFOR_C PF01314.13 EXF79368.1 - 0.043 12.4 0.0 0.067 11.8 0.0 1.1 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 Miro PF08477.8 EXF79368.1 - 0.045 14.2 0.0 0.086 13.3 0.0 1.4 1 0 0 1 1 1 0 Miro-like protein Zeta_toxin PF06414.7 EXF79368.1 - 0.049 12.7 0.0 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_18 PF13238.1 EXF79368.1 - 0.052 13.8 0.0 0.13 12.6 0.0 1.6 2 0 0 2 2 1 0 AAA domain DUF258 PF03193.11 EXF79368.1 - 0.068 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 RNA_helicase PF00910.17 EXF79368.1 - 0.091 12.9 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_21 PF13304.1 EXF79368.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EXF79368.1 - 0.11 12.0 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein DUF2263 PF10021.4 EXF79369.1 - 4.1e-25 88.5 0.0 9e-25 87.4 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) Fungal_trans PF04082.13 EXF79371.1 - 3e-10 39.4 2.7 4.5e-10 38.8 1.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF79371.1 - 5.5e-08 32.5 9.1 9.8e-08 31.7 6.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EXF79372.1 - 6e-77 259.1 16.9 6e-77 259.1 11.7 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF79372.1 - 5.8e-18 64.7 26.6 5.8e-18 64.7 18.4 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF148 PF02520.12 EXF79372.1 - 0.013 15.3 0.1 0.028 14.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF148 Alpha-amylase PF00128.19 EXF79373.1 - 1.7e-94 316.8 0.2 2.9e-94 316.0 0.2 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain hDGE_amylase PF14701.1 EXF79373.1 - 0.0036 16.2 0.0 0.0072 15.2 0.0 1.4 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme Glyco_hydro_42C PF08533.5 EXF79373.1 - 0.019 14.4 0.0 0.058 12.9 0.0 1.8 2 0 0 2 2 2 0 Beta-galactosidase C-terminal domain Peroxidase_2 PF01328.12 EXF79374.1 - 1.1e-29 103.1 0.0 1.5e-29 102.6 0.0 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 FAD_binding_4 PF01565.18 EXF79376.1 - 9e-15 54.3 1.4 1.9e-14 53.2 1.0 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF79376.1 - 2.1e-10 40.3 2.0 4.6e-10 39.2 1.4 1.6 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EXF79376.1 - 0.014 14.5 0.1 0.02 14.0 0.1 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding DUF4231 PF14015.1 EXF79376.1 - 0.019 14.9 0.0 0.059 13.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Adhes-Ig_like PF09085.5 EXF79376.1 - 0.032 14.0 0.0 0.08 12.7 0.0 1.6 1 0 0 1 1 1 0 Adhesion molecule, immunoglobulin-like MFS_1 PF07690.11 EXF79377.1 - 3.7e-19 68.6 52.2 1.7e-09 36.8 12.9 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF79377.1 - 4.2e-12 45.0 15.3 6.6e-12 44.4 10.6 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PUCC PF03209.10 EXF79377.1 - 0.001 17.9 8.6 0.001 17.9 5.9 3.8 3 1 0 4 4 4 2 PUCC protein DUF2530 PF10745.4 EXF79377.1 - 0.17 11.8 5.9 0.29 11.1 1.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2530) NmrA PF05368.8 EXF79378.1 - 1.9e-24 86.2 0.0 2.6e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF79378.1 - 9.4e-09 35.5 0.0 1.3e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EXF79378.1 - 0.015 15.6 0.0 0.038 14.2 0.0 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain UPF0175 PF03683.8 EXF79378.1 - 0.18 11.2 0.9 0.8 9.2 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0175) Asp_Arg_Hydrox PF05118.10 EXF79380.1 - 0.13 12.1 0.0 0.24 11.2 0.0 1.4 1 1 0 1 1 1 0 Aspartyl/Asparaginyl beta-hydroxylase CIA30 PF08547.7 EXF79381.1 - 2.8e-36 124.7 0.0 3.4e-36 124.4 0.0 1.0 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) Epimerase PF01370.16 EXF79384.1 - 1.4e-08 34.4 0.4 5e-05 22.8 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF79384.1 - 1.2e-07 31.8 0.0 2.7e-07 30.7 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EXF79384.1 - 0.00037 19.8 0.4 0.0057 15.9 0.0 2.1 1 1 1 2 2 2 1 NmrA-like family KR PF08659.5 EXF79384.1 - 0.00085 19.0 0.1 0.0023 17.6 0.1 1.7 1 1 0 1 1 1 1 KR domain adh_short PF00106.20 EXF79384.1 - 0.031 14.2 0.1 0.073 12.9 0.1 1.6 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.13 EXF79384.1 - 0.082 12.9 0.3 0.2 11.6 0.1 1.7 2 0 0 2 2 2 0 TrkA-N domain CorA PF01544.13 EXF79385.1 - 6.2e-05 22.1 0.2 9.3e-05 21.5 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SIC PF03482.8 EXF79385.1 - 0.04 13.5 0.1 0.063 12.8 0.1 1.2 1 0 0 1 1 1 0 sic protein DUF4077 PF13295.1 EXF79385.1 - 0.066 12.9 0.1 0.1 12.3 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4077) GMC_oxred_N PF00732.14 EXF79386.1 - 1.4e-31 109.8 0.3 1.2e-30 106.7 0.5 2.2 2 1 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF79386.1 - 6.5e-29 101.0 0.0 1.1e-28 100.3 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EXF79386.1 - 0.0012 17.7 0.0 0.019 13.8 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EXF79386.1 - 0.075 12.9 0.0 0.76 9.6 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF79386.1 - 0.083 12.9 0.0 0.2 11.6 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain RRM_1 PF00076.17 EXF79387.1 - 1e-08 34.6 0.1 1.9e-08 33.7 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF79387.1 - 7.4e-08 32.2 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EXF79387.1 - 0.00032 20.3 0.0 0.00057 19.5 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 EXF79387.1 - 0.011 15.5 0.0 0.019 14.7 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3659 PF12396.3 EXF79389.1 - 3.2e-167 542.4 83.9 2.8e-22 78.1 0.9 10.1 9 0 0 9 9 9 9 Protein of unknown function (DUF3659) DUF3659 PF12396.3 EXF79390.1 - 8.7e-18 63.7 2.7 9.6e-13 47.6 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF3659) U79_P34 PF03064.11 EXF79392.1 - 0.17 11.3 3.1 0.21 11.0 2.2 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Stm1_N PF09598.5 EXF79392.1 - 6.5 7.5 8.3 10 6.9 5.7 1.4 1 0 0 1 1 1 0 Stm1 Phage_lysis PF03245.8 EXF79395.1 - 0.021 14.8 3.2 0.021 14.8 2.2 2.3 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein DivIC PF04977.10 EXF79395.1 - 0.024 14.1 0.6 0.024 14.1 0.4 1.6 2 0 0 2 2 2 0 Septum formation initiator Striatin PF08232.7 EXF79395.1 - 0.13 12.5 5.1 1.7 8.9 0.1 2.3 2 0 0 2 2 2 0 Striatin family DUF3138 PF11336.3 EXF79395.1 - 0.35 9.0 10.9 0.0099 14.1 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Macoilin PF09726.4 EXF79395.1 - 0.39 8.9 11.6 0.58 8.3 8.0 1.3 1 0 0 1 1 1 0 Transmembrane protein Fmp27_WPPW PF10359.4 EXF79395.1 - 0.55 8.5 2.7 0.36 9.1 0.0 1.8 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain FMO-like PF00743.14 EXF79397.1 - 1.2e-18 66.6 1.6 5.7e-17 61.1 0.0 2.4 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EXF79397.1 - 2.2e-18 67.0 0.0 6e-18 65.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF79397.1 - 1.4e-10 41.3 0.0 4.5e-08 33.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF79397.1 - 4.2e-09 35.7 0.1 2.6e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EXF79397.1 - 1.5e-07 31.3 0.6 3.1e-06 27.0 0.1 2.9 2 1 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF79397.1 - 1.9e-05 23.7 0.6 0.15 10.8 0.0 3.0 3 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EXF79397.1 - 0.00099 18.9 1.7 2.4 7.9 0.0 3.8 3 1 0 3 3 3 2 FAD-NAD(P)-binding Thi4 PF01946.12 EXF79397.1 - 0.0027 16.8 0.0 0.007 15.4 0.0 1.6 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EXF79397.1 - 0.0036 16.2 0.0 0.0064 15.3 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EXF79397.1 - 0.064 12.1 0.0 0.35 9.7 0.0 2.2 3 0 0 3 3 3 0 Lycopene cyclase protein Pyr_redox PF00070.22 EXF79397.1 - 0.21 12.0 2.9 4.5 7.7 0.6 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EXF79397.1 - 0.21 10.6 0.6 0.34 9.9 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain Beta-lactamase PF00144.19 EXF79398.1 - 1e-41 143.0 0.0 4.2e-41 141.0 0.0 1.7 1 1 0 1 1 1 1 Beta-lactamase Zn_clus PF00172.13 EXF79399.1 - 0.031 14.1 8.2 0.12 12.3 5.7 2.0 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF79399.1 - 0.054 12.3 0.0 0.12 11.2 0.0 1.6 1 0 0 1 1 1 0 Fungal specific transcription factor domain Ribosomal_60s PF00428.14 EXF79399.1 - 8.2 6.9 15.2 13 6.2 2.2 2.9 2 0 0 2 2 2 0 60s Acidic ribosomal protein FmdA_AmdA PF03069.10 EXF79400.1 - 4.3e-49 167.1 0.0 2.7e-29 102.0 0.0 2.2 1 1 1 2 2 2 2 Acetamidase/Formamidase family DUF3433 PF11915.3 EXF79401.1 - 2.3e-21 75.7 20.7 2e-17 63.0 2.6 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) SnoaL_2 PF12680.2 EXF79402.1 - 1.4e-11 44.6 0.4 2.1e-11 44.1 0.2 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EXF79402.1 - 5.8e-07 29.1 0.3 1.6e-06 27.6 0.2 1.7 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_3 PF13474.1 EXF79402.1 - 2.2e-05 24.4 0.1 5.4e-05 23.2 0.0 1.7 2 1 0 2 2 2 1 SnoaL-like domain DUF4440 PF14534.1 EXF79402.1 - 0.00012 22.2 0.2 0.00026 21.1 0.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) DUF1769 PF08588.5 EXF79404.1 - 1.3e-28 98.7 0.2 3.7e-28 97.2 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1769) Sugar_tr PF00083.19 EXF79405.1 - 1.2e-28 99.9 9.4 1.5e-28 99.5 6.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF79405.1 - 1.6e-14 53.4 14.0 2.2e-14 52.9 9.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily HAD PF12710.2 EXF79406.1 - 1.7e-14 54.4 0.0 2.2e-14 54.0 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EXF79406.1 - 0.0004 20.6 0.0 0.0011 19.2 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase UMPH-1 PF05822.7 EXF79406.1 - 0.0076 15.5 0.0 0.015 14.6 0.0 1.6 1 1 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) Metallophos_3 PF14582.1 EXF79406.1 - 0.058 12.5 0.0 0.08 12.0 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Put_Phosphatase PF06888.7 EXF79406.1 - 0.074 12.2 0.0 3 6.9 0.0 2.1 2 0 0 2 2 2 0 Putative Phosphatase MFS_1 PF07690.11 EXF79407.1 - 3.2e-24 85.2 75.8 1.2e-19 70.2 31.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EXF79407.1 - 0.0023 17.9 8.7 0.039 13.9 0.2 3.6 3 0 0 3 3 3 2 Protein of unknown function (DUF1228) DUF1049 PF06305.6 EXF79407.1 - 0.48 9.9 10.7 0.49 9.9 1.8 3.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1049) eIF-1a PF01176.14 EXF79408.1 - 3.3e-16 58.4 0.2 5.8e-16 57.6 0.1 1.4 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 ALG3 PF05208.8 EXF79409.1 - 7.8e-139 463.0 17.1 9e-139 462.7 11.9 1.0 1 0 0 1 1 1 1 ALG3 protein DUF2567 PF10821.3 EXF79409.1 - 0.2 11.1 4.0 1.2 8.6 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2567) DAO PF01266.19 EXF79410.1 - 1e-26 93.6 0.2 1.4e-26 93.2 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF79410.1 - 0.00012 22.0 0.1 0.00027 20.8 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EXF79410.1 - 0.0036 16.1 0.0 0.0058 15.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EXF79410.1 - 0.011 14.8 0.1 0.011 14.8 0.1 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 EXF79410.1 - 0.022 15.1 0.2 0.057 13.8 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF79410.1 - 0.055 13.3 0.0 0.083 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EXF79410.1 - 0.13 11.2 0.1 0.24 10.4 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 EXF79410.1 - 0.17 10.4 0.1 0.31 9.6 0.0 1.4 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.9 EXF79410.1 - 0.2 10.1 0.1 0.29 9.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Thioredoxin PF00085.15 EXF79411.1 - 5.4e-25 87.0 0.3 1.1e-24 86.1 0.2 1.4 1 0 0 1 1 1 1 Thioredoxin Ank_2 PF12796.2 EXF79411.1 - 1.4e-13 50.9 0.3 3e-06 27.4 0.0 5.2 3 2 1 4 4 4 2 Ankyrin repeats (3 copies) Patatin PF01734.17 EXF79411.1 - 2.3e-09 37.5 0.0 5.2e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 Patatin-like phospholipase NACHT PF05729.7 EXF79411.1 - 9.2e-07 28.6 0.7 9.5e-06 25.3 0.0 2.9 2 1 1 3 3 3 1 NACHT domain AAA_16 PF13191.1 EXF79411.1 - 1e-06 28.8 0.6 9.1e-06 25.7 0.1 2.9 3 0 0 3 3 3 1 AAA ATPase domain Ank_4 PF13637.1 EXF79411.1 - 1e-05 25.8 0.2 0.96 10.0 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 EXF79411.1 - 2.8e-05 23.6 7.4 0.00086 18.9 0.0 4.9 5 0 0 5 5 5 1 Ankyrin repeat Thioredoxin_8 PF13905.1 EXF79411.1 - 0.00011 22.2 0.0 0.00038 20.5 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like Ank_3 PF13606.1 EXF79411.1 - 0.00015 21.6 3.6 0.13 12.5 0.0 4.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.1 EXF79411.1 - 0.00029 20.9 0.9 0.48 10.7 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Thioredoxin_7 PF13899.1 EXF79411.1 - 0.0021 18.0 0.0 0.0078 16.2 0.0 2.0 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.16 EXF79411.1 - 0.0032 17.1 0.0 0.0077 15.9 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.1 EXF79411.1 - 0.007 16.5 0.2 0.036 14.2 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain KAP_NTPase PF07693.9 EXF79411.1 - 0.0071 15.3 0.5 1.5 7.7 0.1 2.5 1 1 0 2 2 2 1 KAP family P-loop domain AAA_22 PF13401.1 EXF79411.1 - 0.076 13.1 0.0 0.75 9.9 0.0 2.5 1 1 1 2 2 2 0 AAA domain Redoxin PF08534.5 EXF79411.1 - 0.085 12.4 0.1 0.28 10.7 0.0 1.9 1 0 0 1 1 1 0 Redoxin Glutaredoxin PF00462.19 EXF79411.1 - 0.1 12.6 0.1 0.35 10.9 0.0 2.0 1 0 0 1 1 1 0 Glutaredoxin AAA_26 PF13500.1 EXF79411.1 - 0.14 11.7 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Fungal_trans_2 PF11951.3 EXF79412.1 - 5.4e-43 147.0 0.0 6.7e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF79412.1 - 4.1e-05 23.3 15.7 8.5e-05 22.3 10.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Tmemb_18A PF09771.4 EXF79413.1 - 5.1 7.0 7.5 2.6 8.0 0.4 2.4 1 1 1 2 2 2 0 Transmembrane protein 188 Glyco_hydro_43 PF04616.9 EXF79414.1 - 3.9e-47 160.7 0.7 3.9e-47 160.7 0.5 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 CBM_6 PF03422.10 EXF79414.1 - 2.3e-36 124.7 1.4 2.3e-36 124.7 0.9 1.7 2 0 0 2 2 2 1 Carbohydrate binding module (family 6) Glyco_hydro_32N PF00251.15 EXF79414.1 - 0.0036 16.7 2.8 0.013 14.8 1.9 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain HET PF06985.6 EXF79415.1 - 5.8e-31 107.5 0.5 1e-30 106.6 0.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RabGGT_insert PF07711.6 EXF79415.1 - 0.0046 16.7 0.0 0.0098 15.7 0.0 1.5 1 0 0 1 1 1 1 Rab geranylgeranyl transferase alpha-subunit, insert domain Dfp1_Him1_M PF08630.5 EXF79415.1 - 0.085 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Dfp1/Him1, central region DEK_C PF08766.6 EXF79415.1 - 0.12 12.2 0.7 8.7 6.2 0.1 3.2 3 0 0 3 3 3 0 DEK C terminal domain OPT PF03169.10 EXF79416.1 - 1.8e-26 92.7 5.6 2e-26 92.5 3.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein PMT_2 PF13231.1 EXF79416.1 - 0.0013 18.6 4.4 0.0018 18.1 3.0 1.1 1 0 0 1 1 1 1 Dolichyl-phosphate-mannose-protein mannosyltransferase Tic20 PF09685.5 EXF79416.1 - 0.089 12.7 9.2 0.17 11.9 6.4 1.5 1 1 0 1 1 1 0 Tic20-like protein OPT PF03169.10 EXF79417.1 - 9.6e-86 288.5 33.4 1.1e-85 288.3 23.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Dioxygenase_C PF00775.16 EXF79418.1 - 3.1e-06 26.5 0.1 7e-06 25.4 0.1 1.6 1 1 0 1 1 1 1 Dioxygenase DUF1929 PF09118.6 EXF79419.1 - 1.2e-26 92.6 0.2 3.6e-26 91.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1929) WSC PF01822.14 EXF79419.1 - 1.5e-24 85.6 26.2 2.6e-13 49.6 8.1 2.7 2 0 0 2 2 2 2 WSC domain Kelch_1 PF01344.20 EXF79419.1 - 5.5e-12 45.0 0.1 0.00046 19.6 0.1 4.0 4 0 0 4 4 4 3 Kelch motif Kelch_6 PF13964.1 EXF79419.1 - 1e-09 38.1 6.9 0.003 17.6 0.0 5.2 5 1 1 6 6 6 2 Kelch motif Kelch_2 PF07646.10 EXF79419.1 - 1.6e-08 33.9 1.1 0.17 11.7 0.0 4.8 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 EXF79419.1 - 1.7e-08 34.1 8.4 0.0043 16.7 0.1 5.5 4 1 1 5 5 5 2 Galactose oxidase, central domain Glyoxal_oxid_N PF07250.6 EXF79419.1 - 1.4e-07 30.8 0.1 0.0035 16.4 0.0 2.3 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_3 PF13415.1 EXF79419.1 - 0.00098 19.2 2.2 2.6 8.3 0.0 4.6 4 1 0 4 4 4 2 Galactose oxidase, central domain Mg_trans_NIPA PF05653.9 EXF79420.1 - 5.4e-91 304.6 20.6 7.7e-91 304.1 14.3 1.1 1 0 0 1 1 1 1 Magnesium transporter NIPA EmrE PF13536.1 EXF79420.1 - 4.7e-08 33.2 5.0 4.7e-08 33.2 3.5 3.0 2 1 1 3 3 3 1 Multidrug resistance efflux transporter EamA PF00892.15 EXF79420.1 - 1.3e-05 25.1 7.1 1.3e-05 25.1 4.9 2.7 2 0 0 2 2 2 1 EamA-like transporter family DUF914 PF06027.7 EXF79420.1 - 0.92 8.2 13.6 2.5 6.8 8.7 2.1 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF914) adh_short_C2 PF13561.1 EXF79422.1 - 2.2e-13 50.5 2.8 1.1e-06 28.5 0.2 2.3 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EXF79422.1 - 1.5e-11 44.5 1.2 1.5e-11 44.5 0.9 1.9 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 EXF79422.1 - 8.7e-07 28.7 1.5 8.7e-07 28.7 1.0 2.1 1 1 1 2 2 2 1 KR domain Saccharop_dh PF03435.13 EXF79422.1 - 5.7e-05 22.2 1.8 0.00018 20.6 0.2 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase Pyr_redox_2 PF07992.9 EXF79422.1 - 6.1e-05 22.9 1.2 0.00013 21.9 0.9 1.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3Beta_HSD PF01073.14 EXF79422.1 - 0.0037 16.0 0.1 0.005 15.5 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family F420_oxidored PF03807.12 EXF79422.1 - 0.02 15.2 0.8 0.02 15.2 0.6 2.7 2 2 2 4 4 4 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EXF79422.1 - 0.021 14.2 0.2 0.038 13.4 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DAO PF01266.19 EXF79422.1 - 3.9 6.2 8.3 2.8 6.7 3.0 2.1 1 1 1 2 2 2 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.14 EXF79423.1 - 1.3e-39 135.1 0.0 2.5e-39 134.2 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EXF79423.1 - 1e-10 41.1 0.0 1.4e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EXF79423.1 - 0.0028 17.4 0.1 0.0067 16.2 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EXF79423.1 - 0.0039 17.5 0.1 0.008 16.5 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_C PF03720.10 EXF79423.1 - 0.012 15.7 0.0 0.94 9.6 0.0 2.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Gp_dh_N PF00044.19 EXF79423.1 - 0.012 15.5 0.1 0.032 14.2 0.1 1.7 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EXF79423.1 - 0.019 15.0 0.1 0.048 13.7 0.1 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.15 EXF79423.1 - 0.026 14.4 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 EXF79423.1 - 0.044 14.3 0.0 0.08 13.4 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.13 EXF79423.1 - 0.044 13.7 0.6 0.37 10.7 0.2 2.4 2 1 0 2 2 2 0 TrkA-N domain GMC_oxred_N PF00732.14 EXF79424.1 - 8.2e-54 182.7 0.5 8.8e-52 176.0 0.3 2.2 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF79424.1 - 7.3e-38 130.1 0.0 1.5e-37 129.0 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EXF79424.1 - 2e-06 26.9 5.5 3.9e-05 22.7 3.6 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EXF79424.1 - 2.9e-06 27.4 0.8 0.045 13.8 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF79424.1 - 8.8e-06 24.8 1.9 0.021 13.6 0.4 2.5 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EXF79424.1 - 6.8e-05 22.8 0.2 0.0002 21.3 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF79424.1 - 0.00094 19.1 0.6 0.44 10.4 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF79424.1 - 0.002 17.1 0.3 0.0032 16.4 0.2 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EXF79424.1 - 0.0022 17.1 0.0 0.0046 16.0 0.0 1.5 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EXF79424.1 - 0.0053 15.2 1.3 0.072 11.5 0.1 2.2 2 0 0 2 2 2 1 HI0933-like protein K_oxygenase PF13434.1 EXF79424.1 - 0.023 13.6 0.2 1.4 7.7 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EXF79424.1 - 0.044 13.5 1.1 0.14 11.9 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EXF79424.1 - 0.12 12.8 1.0 4.7 7.6 0.1 2.8 3 0 0 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase tRNA-synt_2 PF00152.15 EXF79425.1 - 1.5e-68 231.0 0.0 2.3e-68 230.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EXF79425.1 - 1.7e-05 24.5 0.0 2.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EXF79425.1 - 0.11 11.7 0.0 2.3 7.3 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) DUF2263 PF10021.4 EXF79426.1 - 9.5e-16 58.1 0.0 1.6e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2263) TraG-D_C PF12696.2 EXF79426.1 - 0.042 13.7 1.6 0.069 13.0 1.1 1.3 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG Pex26 PF07163.7 EXF79426.1 - 0.12 11.2 1.2 0.21 10.4 0.8 1.3 1 0 0 1 1 1 0 Pex26 protein SR-25 PF10500.4 EXF79426.1 - 5.9 6.2 18.6 11 5.4 12.9 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RAP1 PF07218.6 EXF79426.1 - 8 4.4 9.2 11 4.0 6.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Sec23_trunk PF04811.10 EXF79427.1 - 2.1e-50 171.3 0.0 5.5e-50 170.0 0.0 1.7 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EXF79427.1 - 5e-25 86.9 0.1 9.1e-25 86.0 0.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EXF79427.1 - 6.9e-18 64.9 0.0 1.3e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EXF79427.1 - 5.5e-16 57.8 5.2 1.1e-15 56.8 3.6 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EXF79427.1 - 3.9e-06 26.4 0.0 9.9e-06 25.1 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat CPSF100_C PF13299.1 EXF79428.1 - 4.2e-46 157.0 0.9 4.2e-46 157.0 0.7 2.0 3 0 0 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal Beta-Casp PF10996.3 EXF79428.1 - 5.9e-27 94.0 0.0 2e-25 89.1 0.0 3.1 3 0 0 3 3 3 1 Beta-Casp domain RMMBL PF07521.7 EXF79428.1 - 1.7e-06 27.7 0.0 4.3e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Fungal_trans PF04082.13 EXF79429.1 - 7.2e-08 31.6 0.0 1.3e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_2 PF00797.12 EXF79430.1 - 9.1e-42 143.2 0.1 1.2e-41 142.8 0.1 1.1 1 0 0 1 1 1 1 N-acetyltransferase TIM PF00121.13 EXF79431.1 - 4.7e-59 199.3 0.0 5.3e-59 199.2 0.0 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase LacAB_rpiB PF02502.13 EXF79432.1 - 5e-41 139.6 0.3 5.8e-41 139.4 0.2 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase Dak1 PF02733.12 EXF79433.1 - 1.2e-108 362.5 0.0 1.6e-108 362.1 0.0 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EXF79433.1 - 8.8e-42 142.7 0.4 1.4e-41 142.0 0.3 1.3 1 0 0 1 1 1 1 DAK2 domain DUF759 PF05537.6 EXF79433.1 - 0.092 11.4 0.2 0.15 10.8 0.1 1.2 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF759) Fungal_trans PF04082.13 EXF79434.1 - 8.1e-22 77.3 0.0 1.3e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF79434.1 - 0.16 11.8 16.7 0.46 10.4 11.6 1.8 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain MamL-1 PF09596.5 EXF79434.1 - 0.19 11.5 4.2 0.48 10.2 2.9 1.6 1 0 0 1 1 1 0 MamL-1 domain ABC_tran_2 PF12848.2 EXF79434.1 - 1.9 8.3 6.0 2.5 7.9 0.5 2.4 2 0 0 2 2 2 0 ABC transporter Cut12 PF11500.3 EXF79436.1 - 0.34 10.6 4.2 0.32 10.6 0.7 2.2 1 1 1 2 2 2 0 Spindle pole body formation-associated protein Abhydrolase_6 PF12697.2 EXF79437.1 - 6.1e-27 94.9 0.0 8.7e-27 94.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF79437.1 - 7.6e-14 51.8 0.0 6.2e-13 48.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF79437.1 - 1.9e-13 50.3 0.0 3.1e-13 49.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EXF79437.1 - 0.00011 22.4 0.0 0.00018 21.8 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF915 PF06028.6 EXF79437.1 - 0.00032 19.8 0.0 0.021 13.8 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 EXF79437.1 - 0.00088 18.7 0.2 0.0018 17.7 0.1 1.5 1 1 0 2 2 2 1 Putative esterase Lipase_3 PF01764.20 EXF79437.1 - 0.0027 17.3 0.0 0.0044 16.6 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Chlorophyllase PF07224.6 EXF79437.1 - 0.012 14.4 0.1 0.034 12.9 0.1 1.6 1 1 0 1 1 1 0 Chlorophyllase Hydrolase_4 PF12146.3 EXF79437.1 - 0.065 13.0 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase PGAP1 PF07819.8 EXF79437.1 - 0.074 12.6 0.1 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Chlorophyllase2 PF12740.2 EXF79437.1 - 0.11 11.2 0.0 0.38 9.5 0.0 1.7 1 1 0 1 1 1 0 Chlorophyllase enzyme UPF0227 PF05728.7 EXF79437.1 - 0.13 11.9 0.1 0.29 10.8 0.1 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) CFEM PF05730.6 EXF79438.1 - 1.1e-11 44.3 12.3 2.2e-11 43.3 8.6 1.5 1 0 0 1 1 1 1 CFEM domain NAD_binding_4 PF07993.7 EXF79439.1 - 3.1e-37 127.8 0.0 5e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EXF79439.1 - 2.5e-34 118.4 0.0 4.5e-34 117.5 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EXF79439.1 - 2.6e-10 40.1 0.0 5.9e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EXF79439.1 - 7.4e-05 22.7 0.1 0.00023 21.1 0.1 1.9 1 0 0 1 1 1 1 short chain dehydrogenase PP-binding PF00550.20 EXF79439.1 - 0.00047 20.3 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.5 EXF79439.1 - 0.0027 17.4 0.2 0.0095 15.6 0.0 2.0 2 0 0 2 2 2 1 KR domain MFS_1 PF07690.11 EXF79440.1 - 3.3e-33 114.8 16.2 4.1e-33 114.5 11.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF79440.1 - 5.5e-12 44.9 14.5 8.4e-12 44.3 10.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter DUF2910 PF11139.3 EXF79440.1 - 0.0028 16.8 7.8 0.03 13.4 1.6 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF2910) Cu-oxidase_2 PF07731.9 EXF79441.1 - 1.5e-23 82.8 3.4 5.8e-22 77.6 1.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EXF79441.1 - 6.4e-21 74.2 0.0 1.8e-20 72.8 0.0 1.8 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.17 EXF79441.1 - 1.5e-05 24.9 0.0 0.0011 18.9 0.0 2.7 3 0 0 3 3 3 1 Multicopper oxidase Glyco_hydro_11 PF00457.12 EXF79443.1 - 7.7e-80 266.5 26.6 9.1e-80 266.3 18.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 NPR3 PF03666.8 EXF79444.1 - 2.9 6.3 4.0 3.7 5.9 2.8 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SRP-alpha_N PF04086.8 EXF79444.1 - 4.7 6.5 13.9 5.3 6.3 9.7 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ank_2 PF12796.2 EXF79445.1 - 2.3e-05 24.6 0.0 0.85 9.9 0.1 3.5 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) HHH_4 PF14490.1 EXF79445.1 - 0.17 11.6 0.2 21 4.9 0.0 2.9 2 1 1 3 3 3 0 Helix-hairpin-helix containing domain Aminotran_1_2 PF00155.16 EXF79446.1 - 1.8e-16 60.0 0.0 2.3e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EXF79446.1 - 1.5e-05 23.7 0.0 4.3e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase DegT_DnrJ_EryC1 PF01041.12 EXF79446.1 - 0.0018 17.3 0.3 0.006 15.6 0.0 1.8 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Fungal_trans PF04082.13 EXF79447.1 - 6.1e-07 28.5 0.1 1e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain NAD_binding_10 PF13460.1 EXF79448.1 - 3.2e-11 43.5 0.2 5.3e-11 42.8 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EXF79448.1 - 4e-09 35.9 0.2 8.3e-09 34.8 0.1 1.5 2 0 0 2 2 2 1 Saccharopine dehydrogenase NmrA PF05368.8 EXF79448.1 - 4.2e-07 29.4 0.3 7.6e-07 28.6 0.2 1.4 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EXF79448.1 - 5e-07 29.3 0.1 0.00038 19.9 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EXF79448.1 - 1.7e-06 27.1 0.2 0.00019 20.4 0.1 2.4 1 1 0 1 1 1 1 Male sterility protein TrkA_N PF02254.13 EXF79448.1 - 2.6e-06 27.4 0.2 5.3e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 TrkA-N domain 3Beta_HSD PF01073.14 EXF79448.1 - 6.7e-06 25.0 0.0 0.00012 20.9 0.1 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EXF79448.1 - 0.0012 19.0 0.1 0.0023 18.2 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EXF79448.1 - 0.0021 18.4 0.1 0.0049 17.2 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 EXF79448.1 - 0.0069 16.3 0.8 0.033 14.0 0.5 2.0 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EXF79448.1 - 0.025 13.4 0.0 0.038 12.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein MFS_1 PF07690.11 EXF79449.1 - 1e-24 86.9 33.6 1.2e-24 86.6 23.3 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily CoA_transf_3 PF02515.12 EXF79450.1 - 1.4e-58 197.2 0.0 2.2e-58 196.6 0.0 1.3 1 0 0 1 1 1 1 CoA-transferase family III Acyl-CoA_dh_1 PF00441.19 EXF79451.1 - 3.7e-32 111.4 2.6 7.4e-32 110.5 1.8 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EXF79451.1 - 2.4e-19 69.9 0.2 5.2e-19 68.8 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EXF79451.1 - 1.4e-16 60.9 3.2 1.4e-16 60.9 2.2 2.0 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EXF79451.1 - 5.4e-15 54.6 0.1 1.5e-14 53.2 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Fungal_trans PF04082.13 EXF79452.1 - 2.6e-32 111.7 0.0 3.7e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF79452.1 - 2.6e-07 30.4 10.0 5.9e-07 29.2 7.0 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MaoC_dehydrat_N PF13452.1 EXF79453.1 - 0.0083 15.9 0.1 0.13 12.0 0.0 2.2 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase FAD_binding_3 PF01494.14 EXF79454.1 - 3.6e-13 49.3 3.3 4e-10 39.2 0.3 3.0 2 2 0 2 2 2 2 FAD binding domain DAO PF01266.19 EXF79454.1 - 4.3e-05 22.5 0.1 0.026 13.4 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF79454.1 - 0.0062 16.5 0.2 0.015 15.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 EXF79454.1 - 0.048 13.6 0.1 0.096 12.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain 3HCDH_N PF02737.13 EXF79454.1 - 0.066 12.8 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_2 PF00890.19 EXF79454.1 - 0.078 11.8 0.3 0.15 10.8 0.2 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 EXF79454.1 - 0.082 12.7 0.1 0.42 10.4 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 EXF79454.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Shikimate_DH PF01488.15 EXF79454.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Lactamase_B PF00753.22 EXF79455.1 - 3.6e-09 36.5 0.4 5.7e-09 35.9 0.3 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.1 EXF79455.1 - 1.3e-07 31.4 0.0 4.8e-06 26.3 0.0 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.2 EXF79455.1 - 0.00011 21.8 0.0 0.0002 20.9 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain 7TM-7TMR_HD PF07698.6 EXF79458.1 - 0.12 11.7 0.2 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase Pectinesterase PF01095.14 EXF79459.1 - 1.9e-48 164.6 4.6 2.3e-48 164.2 3.2 1.1 1 0 0 1 1 1 1 Pectinesterase MFS_1 PF07690.11 EXF79461.1 - 1.1e-34 119.7 24.8 1.7e-34 119.1 17.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1616 PF07760.6 EXF79461.1 - 0.0047 16.0 5.1 0.11 11.6 1.3 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1616) Amidase PF01425.16 EXF79462.1 - 2.1e-49 168.5 0.0 8.2e-49 166.6 0.0 1.8 1 1 0 1 1 1 1 Amidase Pkinase PF00069.20 EXF79464.1 - 5.5e-21 74.8 0.0 2.3e-20 72.8 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF79464.1 - 7.9e-08 31.6 3.1 0.0056 15.7 0.4 3.4 3 1 0 3 3 3 2 Protein tyrosine kinase APH PF01636.18 EXF79464.1 - 0.02 14.6 1.2 0.32 10.6 0.0 3.0 2 2 1 4 4 4 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EXF79464.1 - 0.059 12.3 0.0 7.6 5.4 0.0 2.1 2 0 0 2 2 2 0 Kinase-like MFS_1 PF07690.11 EXF79465.1 - 2.7e-34 118.4 30.0 2.7e-34 118.4 20.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Chitin_synth_2 PF03142.10 EXF79465.1 - 0.1 10.9 1.2 0.16 10.3 0.8 1.2 1 0 0 1 1 1 0 Chitin synthase DUF1109 PF06532.6 EXF79465.1 - 2.9 7.2 15.2 1.4 8.3 4.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1109) dCMP_cyt_deam_1 PF00383.17 EXF79467.1 - 1.6e-07 30.8 0.0 2.3e-07 30.4 0.0 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region SAMP PF05924.6 EXF79467.1 - 0.068 12.3 0.3 0.14 11.3 0.2 1.5 1 0 0 1 1 1 0 SAMP Motif Terpene_synth_C PF03936.11 EXF79468.1 - 6.1e-18 65.0 0.5 8.6e-18 64.5 0.4 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain CCDC50_N PF15295.1 EXF79468.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus p450 PF00067.17 EXF79469.1 - 8.3e-58 196.0 0.0 9.2e-58 195.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Tannase PF07519.6 EXF79470.1 - 7.2e-113 377.8 0.2 1e-112 377.2 0.2 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 EXF79470.1 - 0.0041 16.8 0.0 3 7.6 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EXF79470.1 - 0.02 14.3 0.1 0.23 10.8 0.0 2.2 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.15 EXF79470.1 - 0.021 14.3 0.1 0.13 11.7 0.0 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EXF79470.1 - 0.076 12.2 0.4 1.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ank_2 PF12796.2 EXF79471.1 - 1.9e-110 361.4 0.0 5.7e-19 68.2 0.0 9.0 2 2 10 12 12 12 12 Ankyrin repeats (3 copies) Ank PF00023.25 EXF79471.1 - 6.1e-66 215.1 9.0 7.7e-08 31.7 0.0 16.3 16 0 0 16 16 16 12 Ankyrin repeat Ank_4 PF13637.1 EXF79471.1 - 1.4e-56 187.8 3.7 1.8e-07 31.4 0.0 12.9 10 3 4 14 14 14 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF79471.1 - 3.6e-53 172.2 3.5 0.00019 21.3 0.0 16.8 18 0 0 18 18 16 9 Ankyrin repeat Ank_5 PF13857.1 EXF79471.1 - 2.7e-49 164.0 4.2 2.2e-05 24.5 0.0 14.8 10 3 5 15 15 15 9 Ankyrin repeats (many copies) NACHT PF05729.7 EXF79471.1 - 6.6e-08 32.3 0.0 1.9e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 EXF79471.1 - 0.04 13.6 0.0 0.13 12.0 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 EXF79471.1 - 0.047 14.5 0.0 0.31 11.8 0.0 2.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EXF79471.1 - 0.047 13.8 0.0 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 EXF79471.1 - 0.054 13.1 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein IstB_IS21 PF01695.12 EXF79471.1 - 0.058 12.8 0.1 0.13 11.7 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.1 EXF79471.1 - 0.065 13.2 0.2 0.49 10.3 0.0 2.6 2 1 0 2 2 2 0 AAA ATPase domain AFG1_ATPase PF03969.11 EXF79471.1 - 0.12 11.1 0.0 0.53 9.0 0.0 1.9 2 0 0 2 2 2 0 AFG1-like ATPase AAA_22 PF13401.1 EXF79471.1 - 0.13 12.3 0.0 0.47 10.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EXF79471.1 - 0.26 11.1 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 EXF79471.1 - 0.37 10.6 0.0 0.81 9.4 0.0 1.5 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Arch_ATPase PF01637.13 EXF79471.1 - 0.4 10.3 0.0 0.83 9.2 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase KAP_NTPase PF07693.9 EXF79471.1 - 0.49 9.3 0.0 9 5.1 0.0 2.1 2 0 0 2 2 2 0 KAP family P-loop domain XPG_I PF00867.13 EXF79472.1 - 1.4e-29 102.0 0.7 2.1e-29 101.3 0.0 1.7 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.12 EXF79472.1 - 1.8e-29 101.9 0.0 4.6e-29 100.6 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.15 EXF79472.1 - 2e-05 24.7 0.5 0.00021 21.4 0.0 2.7 3 0 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.2 EXF79472.1 - 0.043 13.7 0.0 0.12 12.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif HXXSHH PF07586.6 EXF79472.1 - 1.1 8.1 3.6 1.7 7.5 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) Acyl-CoA_dh_1 PF00441.19 EXF79473.1 - 1.6e-39 135.3 0.4 2.4e-39 134.8 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EXF79473.1 - 9.9e-21 73.0 0.2 2e-20 72.0 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Cyt-b5 PF00173.23 EXF79473.1 - 2.2e-19 69.0 0.4 4e-19 68.1 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_N PF02771.11 EXF79473.1 - 1.9e-16 60.6 0.0 4.5e-16 59.4 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EXF79473.1 - 5.5e-07 29.9 0.0 9.7e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Haemolytic PF01809.13 EXF79474.1 - 5.7 6.6 8.0 0.87 9.2 0.3 2.4 2 0 0 2 2 2 0 Haemolytic domain Dabb PF07876.7 EXF79475.1 - 6.2e-21 74.6 0.1 7e-21 74.4 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain E1_DerP2_DerF2 PF02221.10 EXF79477.1 - 4.4e-26 91.6 0.7 5.3e-26 91.4 0.5 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EXF79477.1 - 0.015 15.2 0.1 0.029 14.4 0.0 1.5 1 1 0 1 1 1 0 ML-like domain ATP-synt_F PF01990.12 EXF79478.1 - 1.3e-32 112.0 0.1 1.5e-32 111.8 0.1 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DUF2418 PF10332.4 EXF79479.1 - 1.7e-35 121.3 0.7 4.7e-35 119.8 0.4 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) MCM_N PF14551.1 EXF79481.1 - 0.031 14.7 0.0 0.045 14.2 0.0 1.3 1 0 0 1 1 1 0 MCM N-terminal domain Aconitase PF00330.15 EXF79483.1 - 2.8e-179 596.4 0.8 3.4e-179 596.1 0.0 1.4 2 0 0 2 2 2 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EXF79483.1 - 1.4e-43 148.1 0.0 2.5e-43 147.3 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain Methyltransf_16 PF10294.4 EXF79484.1 - 1.3e-10 41.0 0.0 0.00027 20.4 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_23 PF13489.1 EXF79484.1 - 0.0037 16.9 0.0 0.0063 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain ORC6 PF05460.8 EXF79484.1 - 0.03 13.4 1.5 0.044 12.8 1.0 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Methyltransf_18 PF12847.2 EXF79484.1 - 0.074 13.6 0.0 0.19 12.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain SSP160 PF06933.6 EXF79484.1 - 2.7 5.8 14.0 4.4 5.1 9.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Enterotoxin_a PF01375.12 EXF79486.1 - 2.2e-46 158.2 0.1 2.7e-46 157.9 0.1 1.0 1 0 0 1 1 1 1 Heat-labile enterotoxin alpha chain MFS_1 PF07690.11 EXF79487.1 - 8.6e-34 116.7 53.6 1.2e-24 86.6 16.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EXF79487.1 - 4.7e-06 26.2 2.3 0.013 15.2 0.0 3.4 3 0 0 3 3 3 2 MFS_1 like family MFS_2 PF13347.1 EXF79487.1 - 0.0006 18.3 8.0 0.0006 18.3 5.5 3.4 1 1 2 3 3 3 2 MFS/sugar transport protein DUF2975 PF11188.3 EXF79487.1 - 0.0025 17.5 0.0 0.0025 17.5 0.0 3.8 4 1 2 6 6 6 1 Protein of unknown function (DUF2975) Dynamin_N PF00350.18 EXF79488.1 - 3.3e-31 108.3 0.0 9.3e-31 106.8 0.0 1.8 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EXF79488.1 - 7e-18 64.4 0.0 1.3e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 EXF79488.1 - 3.4e-05 23.7 0.0 0.00024 21.0 0.0 2.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EXF79488.1 - 0.0079 16.6 0.0 0.019 15.4 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein FeoB_N PF02421.13 EXF79488.1 - 0.12 11.6 0.0 9.4 5.4 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Cwf_Cwc_15 PF04889.7 EXF79488.1 - 3.2 7.4 10.5 0.45 10.1 3.9 2.1 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein His_Phos_2 PF00328.17 EXF79489.1 - 6.9e-58 196.6 0.0 8.1e-58 196.4 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Bromodomain PF00439.20 EXF79491.1 - 3.3e-18 65.3 0.0 1e-17 63.8 0.0 2.0 2 0 0 2 2 2 1 Bromodomain BTB PF00651.26 EXF79491.1 - 0.00012 21.9 0.0 0.00041 20.3 0.0 1.8 2 0 0 2 2 2 1 BTB/POZ domain Ribonuclease_T2 PF00445.13 EXF79492.1 - 5.5e-27 94.6 0.4 9.3e-27 93.8 0.3 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family Sec62 PF03839.11 EXF79493.1 - 1.9e-51 174.6 0.4 1.9e-51 174.6 0.3 1.8 2 0 0 2 2 2 1 Translocation protein Sec62 Calsarcin PF05556.6 EXF79493.1 - 0.12 11.5 9.3 0.041 13.0 2.2 2.1 2 0 0 2 2 2 0 Calcineurin-binding protein (Calsarcin) SelP_N PF04592.9 EXF79493.1 - 0.52 9.6 12.3 0.91 8.8 8.5 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Corona_M PF01635.13 EXF79493.1 - 4.6 6.1 8.2 7.9 5.3 5.7 1.3 1 0 0 1 1 1 0 Coronavirus M matrix/glycoprotein E1-E2_ATPase PF00122.15 EXF79495.1 - 2.5e-49 167.4 9.7 1.1e-48 165.2 5.3 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EXF79495.1 - 2.3e-29 103.3 1.9 3.1e-29 102.9 0.6 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EXF79495.1 - 1.7e-11 44.6 0.0 4.1e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EXF79495.1 - 7.6e-10 38.7 0.0 1e-08 35.1 0.0 2.7 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 EXF79495.1 - 0.029 13.9 1.6 3.6 7.0 0.0 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase OPT PF03169.10 EXF79497.1 - 4.2e-205 682.8 40.9 4.9e-205 682.6 28.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein UPF0697 PF15117.1 EXF79497.1 - 0.11 12.2 0.0 0.62 9.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0697 PBP_GOBP PF01395.17 EXF79498.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 PBP/GOBP family NPP1 PF05630.6 EXF79499.1 - 1.3e-32 113.1 0.2 2.8e-32 112.1 0.1 1.5 1 1 0 1 1 1 1 Necrosis inducing protein (NPP1) GFO_IDH_MocA PF01408.17 EXF79500.1 - 6.5e-21 75.0 0.1 1.3e-20 74.1 0.0 1.5 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EXF79500.1 - 9.7e-07 28.5 0.0 2.7e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_3 PF03447.11 EXF79500.1 - 5.6e-05 23.5 0.0 0.00011 22.5 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain AAA_33 PF13671.1 EXF79500.1 - 0.0023 17.8 0.0 0.0045 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Semialdhyde_dh PF01118.19 EXF79500.1 - 0.0028 17.9 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DUF1593 PF07632.6 EXF79501.1 - 1.5e-82 276.8 0.2 1.9e-82 276.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.10 EXF79501.1 - 0.0062 14.9 0.0 0.0085 14.4 0.0 1.1 1 0 0 1 1 1 1 REJ domain Pilin PF00114.14 EXF79502.1 - 0.02 15.5 0.3 0.023 15.4 0.2 1.1 1 0 0 1 1 1 0 Pilin (bacterial filament) Somatostatin PF03002.10 EXF79502.1 - 0.13 11.9 0.9 0.39 10.3 0.6 1.8 1 0 0 1 1 1 0 Somatostatin/Cortistatin family Peptidase_M14 PF00246.19 EXF79503.1 - 7.7e-74 248.7 0.1 9.2e-74 248.5 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CorA PF01544.13 EXF79504.1 - 4.9e-44 150.5 0.2 6.8e-44 150.0 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein p450 PF00067.17 EXF79505.1 - 1.6e-61 208.2 0.0 2.2e-61 207.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Transferase PF02458.10 EXF79505.1 - 3.1e-26 91.7 0.0 1.9e-20 72.7 0.0 2.3 2 1 0 2 2 2 2 Transferase family Cyt-b5 PF00173.23 EXF79506.1 - 1.4e-20 72.8 0.3 2.7e-20 71.9 0.1 1.5 1 1 1 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain KR PF08659.5 EXF79508.1 - 1.7e-59 200.5 1.3 4.6e-59 199.1 0.3 2.2 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 EXF79508.1 - 8.8e-57 192.8 0.5 3.3e-56 190.9 0.1 2.2 2 0 0 2 2 2 1 Acyl transferase domain PS-DH PF14765.1 EXF79508.1 - 2.2e-54 184.6 0.0 4.1e-54 183.7 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EXF79508.1 - 4.6e-45 153.5 0.7 1.3e-43 148.8 0.1 2.6 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EXF79508.1 - 3.7e-36 123.5 0.1 9.5e-36 122.2 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 EXF79508.1 - 4.1e-36 124.7 0.0 4.7e-21 75.4 0.0 2.7 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain PP-binding PF00550.20 EXF79508.1 - 0.0005 20.2 0.1 0.0013 18.9 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.21 EXF79508.1 - 0.0077 15.7 0.0 0.029 13.9 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase YflT PF11181.3 EXF79508.1 - 0.16 12.1 0.0 0.54 10.4 0.0 1.9 1 0 0 1 1 1 0 Heat induced stress protein YflT FSH1 PF03959.8 EXF79509.1 - 5.5e-27 94.5 0.5 7.3e-26 90.9 0.3 2.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.11 EXF79509.1 - 0.0077 15.7 0.1 0.18 11.1 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase MFS_1 PF07690.11 EXF79510.1 - 5.2e-41 140.5 38.9 5.2e-41 140.5 26.9 1.7 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EXF79510.1 - 6.8e-09 34.4 23.4 1.2e-08 33.6 16.2 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ketoacyl-synt PF00109.21 EXF79511.1 - 1.3e-70 237.7 0.0 2.2e-70 237.0 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EXF79511.1 - 9.8e-57 191.5 0.0 1e-55 188.1 0.0 2.7 3 0 0 3 3 2 1 KR domain PS-DH PF14765.1 EXF79511.1 - 6e-51 173.3 0.0 1e-50 172.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Acyl_transf_1 PF00698.16 EXF79511.1 - 2.4e-50 171.7 0.0 3.5e-50 171.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EXF79511.1 - 3.1e-43 147.5 0.2 5.8e-42 143.4 0.0 2.5 2 0 0 2 2 2 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EXF79511.1 - 4.9e-40 136.0 0.1 1.3e-39 134.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EXF79511.1 - 6.2e-20 71.0 0.4 2.7e-19 69.0 0.1 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EXF79511.1 - 7.4e-19 68.0 0.0 2.9e-18 66.1 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EXF79511.1 - 5.8e-14 53.0 0.0 4.2e-13 50.2 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EXF79511.1 - 1.2e-11 44.6 0.0 8.4e-11 41.8 0.0 2.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF79511.1 - 5.2e-09 36.4 0.0 1.8e-08 34.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF79511.1 - 4.8e-08 32.7 0.0 1.4e-07 31.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF79511.1 - 1.8e-07 31.7 0.0 7.2e-07 29.7 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF79511.1 - 1.2e-05 24.6 0.0 2.2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ADH_N PF08240.7 EXF79511.1 - 0.00016 21.4 0.0 0.00036 20.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_25 PF13649.1 EXF79511.1 - 0.0014 18.9 0.0 0.0043 17.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EXF79511.1 - 0.0033 17.6 0.1 0.012 15.8 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_16 PF10294.4 EXF79511.1 - 0.043 13.2 0.0 0.094 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase UPF0300 PF08594.5 EXF79511.1 - 0.054 12.4 0.1 0.12 11.3 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0300) Saccharop_dh PF03435.13 EXF79511.1 - 0.077 11.9 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EXF79511.1 - 0.1 12.6 0.6 0.5 10.3 0.1 2.4 2 0 0 2 2 2 0 NADH(P)-binding Methyltransf_28 PF02636.12 EXF79511.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Spermine_synth PF01564.12 EXF79511.1 - 0.14 11.0 0.0 0.33 9.8 0.0 1.5 1 0 0 1 1 1 0 Spermine/spermidine synthase Glyco_hydro_42M PF08532.5 EXF79511.1 - 0.24 10.5 0.0 0.6 9.2 0.0 1.6 1 0 0 1 1 1 0 Beta-galactosidase trimerisation domain RepB PF07506.6 EXF79511.1 - 0.27 11.0 0.0 5.4 6.8 0.0 2.4 2 0 0 2 2 2 0 RepB plasmid partitioning protein Methyltransf_8 PF05148.10 EXF79511.1 - 0.31 10.6 0.0 0.58 9.7 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase p450 PF00067.17 EXF79513.1 - 3.9e-63 213.5 0.0 5.3e-63 213.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 TauD PF02668.11 EXF79514.1 - 1.8e-52 178.5 0.2 2.2e-52 178.3 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 EXF79515.1 - 1.4e-30 106.2 12.8 1.4e-30 106.2 8.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily A_deaminase PF00962.17 EXF79516.1 - 3.1e-36 124.9 0.0 5.9e-36 124.0 0.0 1.4 1 1 0 1 1 1 1 Adenosine/AMP deaminase MFS_1 PF07690.11 EXF79517.1 - 1.1e-30 106.5 31.8 1.5e-30 106.1 22.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF2196 PF09962.4 EXF79518.1 - 2.9e-20 71.7 2.4 4.8e-20 71.1 1.6 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2196) zf-ribbon_3 PF13248.1 EXF79518.1 - 0.1 11.8 0.4 0.18 11.0 0.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Exo5 PF09810.4 EXF79521.1 - 1.2e-110 369.7 0.0 1.5e-110 369.4 0.0 1.1 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease AF0941-like PF14591.1 EXF79523.1 - 0.016 15.2 0.2 0.02 14.9 0.2 1.1 1 0 0 1 1 1 0 AF0941-like Methyltransf_23 PF13489.1 EXF79524.1 - 6e-18 65.0 0.0 9.8e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF79524.1 - 2.3e-11 44.2 0.0 9.4e-11 42.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF79524.1 - 7e-10 38.6 0.0 2.8e-09 36.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF79524.1 - 5.2e-08 33.2 0.0 1.1e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF79524.1 - 3.1e-06 27.5 0.0 5.4e-05 23.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EXF79524.1 - 0.00036 19.7 0.0 0.00049 19.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 EXF79524.1 - 0.00068 19.9 0.0 0.002 18.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF79524.1 - 0.0042 16.2 0.0 0.026 13.6 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EXF79524.1 - 0.0053 16.7 0.0 0.013 15.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EXF79524.1 - 0.007 16.3 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EXF79524.1 - 0.048 13.1 0.0 0.097 12.1 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 EXF79524.1 - 0.067 12.5 0.0 0.36 10.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain CheR PF01739.13 EXF79524.1 - 0.15 11.2 0.0 0.28 10.4 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Zn_clus PF00172.13 EXF79525.1 - 3e-07 30.2 9.9 3e-07 30.2 6.9 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF79525.1 - 0.015 13.9 0.1 0.024 13.2 0.0 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain Tannase PF07519.6 EXF79526.1 - 1e-94 317.9 6.2 1.4e-94 317.4 4.3 1.2 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 EXF79526.1 - 0.0063 16.2 0.0 0.17 11.6 0.0 2.6 2 1 0 2 2 2 1 Alpha/beta hydrolase family F-box-like PF12937.2 EXF79528.1 - 0.0053 16.4 0.1 0.16 11.7 0.0 2.7 2 0 0 2 2 2 1 F-box-like VGCC_alpha2 PF08473.6 EXF79528.1 - 0.012 15.3 0.0 0.029 14.1 0.0 1.6 1 0 0 1 1 1 0 Neuronal voltage-dependent calcium channel alpha 2acd Pyridox_oxidase PF01243.15 EXF79529.1 - 5.7e-08 32.6 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase TP_methylase PF00590.15 EXF79530.1 - 1.1e-19 70.9 0.1 1.9e-19 70.2 0.1 1.4 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases zf-C2H2_jaz PF12171.3 EXF79531.1 - 1.7e-06 27.9 0.1 2.9e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EXF79531.1 - 4.8e-05 23.4 0.1 8.3e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type DUF1777 PF08648.7 EXF79531.1 - 0.00011 21.9 11.6 0.00011 21.9 8.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) zf-DBF PF07535.7 EXF79531.1 - 0.0095 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 DBF zinc finger zf-U1 PF06220.7 EXF79531.1 - 0.12 11.9 0.1 0.28 10.7 0.0 1.5 1 0 0 1 1 1 0 U1 zinc finger Vfa1 PF08432.5 EXF79531.1 - 0.39 10.7 18.1 0.087 12.8 7.1 2.1 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 UQ_con PF00179.21 EXF79532.1 - 3.8e-36 123.5 0.0 4.8e-36 123.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EXF79532.1 - 0.0058 16.3 0.0 0.013 15.2 0.0 1.5 1 1 0 1 1 1 1 Prokaryotic E2 family B ETX_MTX2 PF03318.8 EXF79533.1 - 0.00088 18.8 5.3 0.0021 17.6 3.7 1.6 1 0 0 1 1 1 1 Clostridium epsilon toxin ETX/Bacillus mosquitocidal toxin MTX2 Aerolysin PF01117.15 EXF79533.1 - 0.001 18.1 1.6 0.0015 17.5 1.1 1.2 1 0 0 1 1 1 1 Aerolysin toxin HET PF06985.6 EXF79534.1 - 1e-30 106.7 5.9 1.9e-30 105.8 4.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) RTA1 PF04479.8 EXF79535.1 - 2.9e-54 183.9 13.9 4.6e-54 183.2 9.7 1.2 1 0 0 1 1 1 1 RTA1 like protein Kei1 PF08552.6 EXF79535.1 - 0.00018 21.2 0.1 0.00047 19.8 0.1 1.6 1 0 0 1 1 1 1 Inositolphosphorylceramide synthase subunit Kei1 Caveolin PF01146.12 EXF79535.1 - 0.44 10.1 4.1 0.14 11.7 0.4 2.0 2 0 0 2 2 2 0 Caveolin F-box-like PF12937.2 EXF79536.1 - 0.14 11.8 0.1 0.14 11.8 0.1 1.7 2 0 0 2 2 2 0 F-box-like adh_short PF00106.20 EXF79537.1 - 2.9e-26 92.3 0.9 3.6e-26 92.0 0.6 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF79537.1 - 6.2e-24 85.0 0.0 7.4e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF79537.1 - 7.7e-11 41.9 0.4 1e-10 41.5 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF79537.1 - 2.2e-05 24.0 0.0 0.037 13.4 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Ldh_1_N PF00056.18 EXF79537.1 - 0.00024 20.9 0.0 0.00038 20.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EXF79537.1 - 0.027 14.2 1.4 0.25 11.1 0.6 2.3 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase p450 PF00067.17 EXF79538.1 - 7.1e-47 159.9 0.0 4e-34 117.9 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 F-box-like PF12937.2 EXF79539.1 - 0.023 14.4 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 F-box-like Peptidase_S10 PF00450.17 EXF79540.1 - 4.4e-72 243.5 0.1 6e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Glyco_hydro_12 PF01670.11 EXF79540.1 - 0.051 13.3 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 12 NmrA PF05368.8 EXF79541.1 - 6e-32 110.7 0.0 2.1e-31 109.0 0.0 1.8 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF79541.1 - 6.3e-12 45.8 0.0 8.6e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF79541.1 - 1.7e-07 30.9 0.1 4.6e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EXF79541.1 - 2.6e-05 24.2 0.5 4.7e-05 23.3 0.3 1.4 1 0 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.12 EXF79541.1 - 0.001 19.4 0.1 0.0026 18.1 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 EXF79541.1 - 0.0011 17.7 0.0 0.0015 17.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EXF79541.1 - 0.0043 16.7 0.2 0.0083 15.8 0.1 1.4 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EXF79541.1 - 0.0057 15.6 0.0 0.0092 14.9 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase DUF2784 PF10861.3 EXF79541.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein of Unknown function (DUF2784) Methyltransf_23 PF13489.1 EXF79542.1 - 3.9e-18 65.6 0.0 6.1e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF79542.1 - 7.4e-09 35.3 0.0 5.8e-08 32.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF79542.1 - 1.3e-08 35.4 0.0 6.2e-08 33.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF79542.1 - 7e-07 29.6 0.0 1.6e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF79542.1 - 8.1e-06 26.2 0.0 3e-05 24.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF79542.1 - 8.4e-05 22.8 0.0 0.0002 21.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF79542.1 - 0.0024 17.9 0.0 0.0068 16.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EXF79542.1 - 0.0081 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 EXF79542.1 - 0.01 14.9 0.0 0.023 13.7 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EXF79542.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EXF79542.1 - 0.011 15.1 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_4 PF02390.12 EXF79542.1 - 0.012 14.6 0.0 0.026 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 EXF79542.1 - 0.014 14.7 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Rapamycin_bind PF08771.6 EXF79542.1 - 0.11 12.5 0.3 0.27 11.3 0.2 1.6 1 0 0 1 1 1 0 Rapamycin binding domain Methyltransf_23 PF13489.1 EXF79543.1 - 1.6e-23 83.2 0.0 2.3e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF79543.1 - 4.1e-10 39.4 0.0 1.7e-09 37.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF79543.1 - 1.1e-08 35.6 0.0 1.8e-07 31.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF79543.1 - 1.1e-07 32.2 0.0 2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF79543.1 - 0.00012 22.5 0.0 0.00084 19.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF79543.1 - 0.00019 21.7 0.0 0.00037 20.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EXF79543.1 - 0.0016 18.4 0.1 0.0037 17.2 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_4 PF02390.12 EXF79543.1 - 0.0026 16.8 0.0 0.0051 15.8 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_26 PF13659.1 EXF79543.1 - 0.0059 16.6 0.0 0.045 13.7 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF79543.1 - 0.0085 15.2 0.0 0.073 12.1 0.0 2.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 EXF79543.1 - 0.011 14.9 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EXF79543.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ferritin_2 PF13668.1 EXF79546.1 - 1.7e-17 63.6 1.5 5.7e-17 61.9 0.2 2.0 2 0 0 2 2 2 1 Ferritin-like domain p450 PF00067.17 EXF79547.1 - 4.5e-55 187.0 0.0 5.4e-55 186.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 APH PF01636.18 EXF79549.1 - 3.4e-14 53.1 0.0 9.8e-14 51.6 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EXF79549.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Ecdysteroid kinase Glyco_trans_1_4 PF13692.1 EXF79550.1 - 8.1e-24 84.3 0.2 5.1e-23 81.7 0.0 2.3 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EXF79550.1 - 4.5e-06 26.2 0.0 9.1e-06 25.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EXF79550.1 - 0.00031 20.9 0.0 0.00064 19.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Cation_efflux PF01545.16 EXF79551.1 - 1.8e-60 204.4 1.3 2.4e-60 204.0 0.9 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 EXF79551.1 - 1.8 7.4 65.0 0.4 9.6 10.7 3.5 1 1 1 2 2 2 0 ZIP Zinc transporter Mito_carr PF00153.22 EXF79552.1 - 4e-57 189.9 5.0 1.3e-19 69.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein His_Phos_1 PF00300.17 EXF79553.1 - 2.6e-08 34.0 0.0 2e-06 27.9 0.0 2.6 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Methyltransf_11 PF08241.7 EXF79554.1 - 2.4e-18 66.3 0.0 4.8e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF79554.1 - 8.5e-16 58.1 0.0 1.5e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF79554.1 - 2e-14 54.0 0.0 4.3e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF79554.1 - 6.1e-14 51.8 0.0 1.2e-13 50.9 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF79554.1 - 7e-14 52.1 0.0 1.7e-13 50.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF79554.1 - 1e-11 44.8 0.0 1.6e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF79554.1 - 1.6e-11 44.2 0.0 3.2e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF79554.1 - 3.9e-10 39.2 0.0 5.1e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EXF79554.1 - 4.4e-10 39.1 0.0 9.3e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.7 EXF79554.1 - 1.7e-07 30.8 0.0 3.7e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 AdoMet dependent proline di-methyltransferase CMAS PF02353.15 EXF79554.1 - 7.9e-06 25.1 0.0 1e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 EXF79554.1 - 2.3e-05 23.8 0.0 2.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) CheR PF01739.13 EXF79554.1 - 3.6e-05 23.1 0.0 0.00055 19.2 0.0 2.2 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_16 PF10294.4 EXF79554.1 - 0.0013 18.1 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase FmrO PF07091.6 EXF79554.1 - 0.0015 17.5 0.0 0.0019 17.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) TehB PF03848.9 EXF79554.1 - 0.0022 17.1 0.0 0.0035 16.5 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.14 EXF79554.1 - 0.0043 16.6 0.0 0.0062 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.13 EXF79554.1 - 0.0048 16.1 0.0 0.0064 15.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase UPF0020 PF01170.13 EXF79554.1 - 0.0071 15.9 0.0 0.038 13.5 0.0 1.9 1 1 1 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_4 PF02390.12 EXF79554.1 - 0.049 12.6 0.0 0.14 11.1 0.0 1.8 1 1 0 1 1 1 0 Putative methyltransferase PMT_C PF11647.3 EXF79554.1 - 0.13 11.8 0.1 0.3 10.7 0.1 1.6 1 0 0 1 1 1 0 C-terminal region of Pasteurella multocida toxin residues 569-1285 Peptidase_C13 PF01650.13 EXF79555.1 - 6.2e-41 140.3 0.3 8.3e-41 139.9 0.2 1.1 1 0 0 1 1 1 1 Peptidase C13 family TFIIIC_delta PF12657.2 EXF79556.1 - 4.7e-13 49.2 0.1 5.3e-06 26.2 0.1 2.6 2 0 0 2 2 2 2 Transcription factor IIIC subunit delta N-term zf-TFIIIC PF12660.2 EXF79556.1 - 3.3e-09 36.5 2.6 6.6e-09 35.5 1.8 1.5 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex CVNH PF08881.5 EXF79557.1 - 0.0064 16.6 0.1 0.012 15.7 0.0 1.4 1 1 0 1 1 1 1 CVNH domain Glyco_hyd_65N_2 PF14498.1 EXF79558.1 - 7.7e-44 150.1 0.0 1.8e-43 148.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain FAD_binding_4 PF01565.18 EXF79558.1 - 1.1e-31 109.1 6.0 1.1e-31 109.1 4.2 2.6 3 0 0 3 3 3 1 FAD binding domain BBE PF08031.7 EXF79558.1 - 2.4e-07 30.5 0.1 6.2e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like Na_Ca_ex PF01699.19 EXF79559.1 - 1.8e-43 147.5 29.9 5.7e-22 77.8 7.8 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF3608 PF12257.3 EXF79560.1 - 7.2e-71 238.3 0.0 1.4e-70 237.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EXF79560.1 - 2.3e-27 94.5 0.2 4.7e-27 93.5 0.1 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Cation_efflux PF01545.16 EXF79561.1 - 1.3e-64 218.0 0.0 1.6e-64 217.7 0.0 1.0 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.17 EXF79561.1 - 0.0028 16.7 0.0 0.0034 16.4 0.0 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter DUF1774 PF08611.5 EXF79561.1 - 0.0072 16.4 0.3 0.058 13.5 0.0 2.5 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1774) FNIP_N PF14636.1 EXF79562.1 - 4e-29 101.7 0.1 4e-29 101.7 0.0 4.5 5 1 0 5 5 5 1 Folliculin-interacting protein N-terminus FNIP_M PF14637.1 EXF79562.1 - 0.0087 15.6 0.2 0.16 11.5 0.0 2.3 1 1 1 2 2 2 1 Folliculin-interacting protein middle domain Baculo_PP31 PF05311.6 EXF79562.1 - 0.097 11.9 0.2 0.18 11.0 0.1 1.4 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Nipped-B_C PF12830.2 EXF79563.1 - 2.5e-49 167.4 3.2 4.6e-49 166.6 1.1 2.3 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EXF79563.1 - 3.6e-10 39.5 1.0 1.5e-09 37.5 0.2 2.4 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.15 EXF79563.1 - 3.8e-07 28.8 0.2 1.2e-05 23.8 0.0 2.9 3 0 0 3 3 3 1 Adaptin N terminal region HEAT PF02985.17 EXF79563.1 - 2.9e-06 26.8 0.6 0.45 10.7 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.2 EXF79563.1 - 6.4e-06 26.1 0.1 0.24 11.2 0.0 3.6 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 TFIIS_C PF01096.13 EXF79564.1 - 3.1e-14 52.2 1.2 3.1e-14 52.2 0.9 3.3 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EXF79564.1 - 0.00025 20.6 7.9 0.0013 18.3 2.7 2.5 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit OrfB_Zn_ribbon PF07282.6 EXF79564.1 - 0.0025 17.4 4.3 0.41 10.3 0.2 2.5 2 0 0 2 2 2 2 Putative transposase DNA-binding domain DZR PF12773.2 EXF79564.1 - 0.038 13.7 9.7 0.18 11.6 1.5 2.5 3 0 0 3 3 2 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 EXF79564.1 - 0.04 13.4 0.2 0.42 10.1 0.1 3.7 4 0 0 4 4 4 0 zinc-ribbon domain C1_1 PF00130.17 EXF79564.1 - 0.049 13.3 1.0 0.049 13.3 0.7 1.8 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Lar_restr_allev PF14354.1 EXF79564.1 - 0.059 13.6 0.4 0.059 13.6 0.3 3.1 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-ribbon_3 PF13248.1 EXF79564.1 - 0.11 11.7 0.2 0.11 11.7 0.1 3.9 3 1 0 3 3 3 0 zinc-ribbon domain DUF1178 PF06676.6 EXF79564.1 - 0.12 12.5 1.6 1 9.5 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1178) Mu-like_Com PF10122.4 EXF79564.1 - 0.69 9.0 4.7 4.3 6.4 1.1 2.3 2 0 0 2 2 2 0 Mu-like prophage protein Com Zn-ribbon_8 PF09723.5 EXF79564.1 - 0.75 9.7 0.1 0.75 9.7 0.1 2.9 3 1 0 3 3 3 0 Zinc ribbon domain DUF2072 PF09845.4 EXF79564.1 - 1.4 8.8 0.0 1.4 8.8 0.0 2.4 1 1 1 2 2 2 0 Zn-ribbon containing protein (DUF2072) IBR PF01485.16 EXF79564.1 - 1.6 8.6 10.0 2.4 8.0 0.7 2.7 2 1 0 2 2 2 0 IBR domain RRN7 PF11781.3 EXF79564.1 - 7.7 6.1 9.0 31 4.1 0.2 3.9 4 0 0 4 4 4 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-trcl PF13451.1 EXF79564.1 - 9.3 5.9 10.4 4.2 7.0 0.1 3.4 3 0 0 3 3 3 0 Probable zinc-binding domain HEAT_2 PF13646.1 EXF79565.1 - 2.5e-30 104.6 8.0 2.1e-15 56.7 0.1 4.1 2 2 2 4 4 4 4 HEAT repeats HEAT_PBS PF03130.11 EXF79565.1 - 1.3e-18 65.4 5.5 0.0028 17.9 0.0 6.7 6 0 0 6 6 6 4 PBS lyase HEAT-like repeat HEAT_EZ PF13513.1 EXF79565.1 - 1e-10 41.7 9.9 0.0016 18.8 0.0 5.0 3 1 2 5 5 5 3 HEAT-like repeat HEAT PF02985.17 EXF79565.1 - 4.7e-06 26.2 7.2 0.68 10.1 0.0 5.9 7 0 0 7 7 7 3 HEAT repeat Arm PF00514.18 EXF79565.1 - 0.0056 16.4 0.4 7.2 6.6 0.0 3.5 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat GRIP PF01465.15 EXF79565.1 - 0.065 12.7 0.0 2.4 7.7 0.0 2.5 2 0 0 2 2 2 0 GRIP domain ParA PF10609.4 EXF79566.1 - 3.3e-33 113.4 0.0 5.9e-33 112.5 0.0 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EXF79566.1 - 4.8e-14 52.2 0.0 7.6e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EXF79566.1 - 2.6e-05 24.2 0.0 6.8e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.10 EXF79566.1 - 0.00032 19.8 0.0 0.0047 16.0 0.2 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 EXF79566.1 - 0.0021 17.1 0.0 0.0051 15.9 0.0 1.6 1 1 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.1 EXF79566.1 - 0.004 16.5 0.1 0.007 15.7 0.1 1.3 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.13 EXF79566.1 - 0.015 14.5 0.0 1.1 8.4 0.0 2.2 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family DUF258 PF03193.11 EXF79566.1 - 0.015 14.4 0.0 0.028 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_26 PF13500.1 EXF79566.1 - 0.021 14.4 0.0 3.1 7.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EXF79566.1 - 0.048 13.2 0.1 0.11 12.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain Zn_Tnp_IS1595 PF12760.2 EXF79566.1 - 0.065 13.0 0.0 0.2 11.4 0.0 1.8 1 0 0 1 1 1 0 Transposase zinc-ribbon domain AAA_19 PF13245.1 EXF79566.1 - 0.067 12.9 0.4 0.82 9.4 0.1 2.3 2 0 0 2 2 2 0 Part of AAA domain RNA_helicase PF00910.17 EXF79566.1 - 0.083 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 RNA helicase VirE PF05272.6 EXF79566.1 - 0.12 11.8 0.0 0.25 10.7 0.0 1.5 2 0 0 2 2 2 0 Virulence-associated protein E Cofilin_ADF PF00241.15 EXF79567.1 - 1.5e-10 41.0 0.0 1.7e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MoCF_biosynth PF00994.19 EXF79568.1 - 5.6e-36 123.0 0.0 8.5e-36 122.5 0.0 1.3 1 0 0 1 1 1 1 Probable molybdopterin binding domain Ras PF00071.17 EXF79570.1 - 3.7e-59 198.7 0.2 4.3e-59 198.5 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EXF79570.1 - 6e-19 68.6 0.0 8.6e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EXF79570.1 - 2.6e-08 33.3 0.0 2.8e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EXF79570.1 - 3.6e-07 29.7 0.1 1.6e-06 27.6 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EXF79570.1 - 0.0021 18.0 0.0 0.0033 17.3 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EXF79570.1 - 0.0048 16.1 0.0 0.0091 15.2 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EXF79570.1 - 0.019 14.1 0.1 0.026 13.6 0.1 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF258 PF03193.11 EXF79570.1 - 0.042 13.0 0.1 0.09 11.9 0.1 1.7 2 1 0 2 2 2 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EXF79570.1 - 0.12 11.9 1.3 1.8 8.0 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein zf-C2H2_jaz PF12171.3 EXF79572.1 - 0.029 14.5 2.1 0.33 11.1 0.0 3.1 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding TPR_MLP1_2 PF07926.7 EXF79572.1 - 0.13 11.9 5.0 0.58 9.8 1.3 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein zf-C2H2 PF00096.21 EXF79572.1 - 0.31 11.4 7.0 2.2 8.8 0.1 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type ING PF12998.2 EXF79573.1 - 0.055 13.7 0.1 0.081 13.2 0.1 1.3 1 0 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding LRR_6 PF13516.1 EXF79575.1 - 0.17 12.0 0.6 4.6 7.6 0.1 3.3 2 1 0 2 2 2 0 Leucine Rich repeat Kelch_5 PF13854.1 EXF79577.1 - 5.2e-14 51.8 5.8 4.2e-13 48.9 0.6 3.7 3 0 0 3 3 3 1 Kelch motif SKG6 PF08693.5 EXF79577.1 - 0.0028 16.9 4.6 0.0028 16.9 3.2 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain Kelch_4 PF13418.1 EXF79577.1 - 0.0061 16.3 5.0 0.35 10.6 0.0 4.5 4 1 0 4 4 4 1 Galactose oxidase, central domain Kelch_1 PF01344.20 EXF79577.1 - 0.016 14.7 1.7 1.6 8.3 0.4 3.3 2 0 0 2 2 2 0 Kelch motif Kelch_2 PF07646.10 EXF79577.1 - 0.26 11.1 3.6 5.4 6.9 0.4 3.6 4 0 0 4 4 4 0 Kelch motif Glyco_transf_9 PF01075.12 EXF79578.1 - 0.038 13.2 0.0 0.066 12.4 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) Spo7 PF03907.8 EXF79580.1 - 4e-68 229.1 0.0 5.6e-68 228.6 0.0 1.1 1 0 0 1 1 1 1 Spo7-like protein Abhydrolase_6 PF12697.2 EXF79581.1 - 2.3e-29 102.8 0.0 4.3e-29 102.0 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF79581.1 - 2.4e-19 69.8 0.0 6.9e-19 68.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF79581.1 - 7.5e-14 51.7 0.0 1.1e-10 41.4 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF915 PF06028.6 EXF79581.1 - 1.4e-06 27.5 0.0 3e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.15 EXF79581.1 - 2.4e-05 23.8 0.0 6.6e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 Putative esterase Abhydrolase_3 PF07859.8 EXF79581.1 - 0.0023 17.5 0.0 0.072 12.6 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EXF79581.1 - 0.0047 16.7 0.0 0.048 13.5 0.0 2.3 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S15 PF02129.13 EXF79581.1 - 0.0074 15.7 0.0 7.5 5.8 0.0 3.0 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) Lipase_3 PF01764.20 EXF79581.1 - 0.012 15.2 0.0 0.023 14.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Chlorophyllase2 PF12740.2 EXF79581.1 - 0.022 13.6 0.0 0.035 12.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Thioesterase PF00975.15 EXF79581.1 - 0.025 14.7 0.0 0.15 12.2 0.0 2.2 1 1 0 1 1 1 0 Thioesterase domain Ser_hydrolase PF06821.8 EXF79581.1 - 0.043 13.4 0.0 0.089 12.3 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase Chlorophyllase PF07224.6 EXF79581.1 - 0.099 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase DUF2305 PF10230.4 EXF79581.1 - 0.19 11.1 0.0 0.42 9.9 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) MARVEL PF01284.18 EXF79583.1 - 1.8e-06 27.8 15.8 2.7e-06 27.2 11.0 1.2 1 0 0 1 1 1 1 Membrane-associating domain Glyco_transf_90 PF05686.7 EXF79584.1 - 2.1e-17 62.9 7.1 2.7e-15 55.9 3.2 2.5 2 1 0 2 2 2 2 Glycosyl transferase family 90 Nucleoside_tran PF01733.13 EXF79586.1 - 1.9e-37 129.0 5.2 1.9e-37 129.0 3.6 2.0 2 0 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.11 EXF79586.1 - 0.0011 17.7 6.5 0.0011 17.7 4.5 3.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Ins_P5_2-kin PF06090.7 EXF79587.1 - 6e-35 120.7 0.5 7.5e-35 120.4 0.3 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase DUF2404 PF10296.4 EXF79589.1 - 0.00017 21.6 0.0 0.00053 20.0 0.0 1.8 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) YEATS PF03366.11 EXF79591.1 - 4.1e-29 100.1 0.2 7.2e-29 99.3 0.1 1.4 1 0 0 1 1 1 1 YEATS family NAD_binding_10 PF13460.1 EXF79592.1 - 1.7e-11 44.4 0.0 7.5e-10 39.1 0.0 2.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF79592.1 - 1.2e-06 28.1 0.0 2.4e-06 27.1 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EXF79592.1 - 0.00083 18.1 0.0 0.0037 16.0 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EXF79592.1 - 0.0092 15.9 0.0 0.091 12.6 0.0 2.2 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EXF79592.1 - 0.021 13.7 0.0 1.9 7.3 0.0 2.9 2 1 1 3 3 3 0 Male sterility protein SYF2 PF08231.7 EXF79593.1 - 8.2e-52 175.3 14.1 8.2e-52 175.3 9.8 1.9 2 0 0 2 2 2 1 SYF2 splicing factor DUF2442 PF10387.4 EXF79594.1 - 0.059 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) Erythro-docking PF09277.6 EXF79594.1 - 0.06 13.0 0.1 0.18 11.5 0.1 1.8 1 0 0 1 1 1 0 Erythronolide synthase, docking Kelch_5 PF13854.1 EXF79595.1 - 3.8e-13 49.0 15.9 1.1e-09 37.9 0.4 5.7 5 0 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 EXF79595.1 - 1.1e-09 37.9 14.0 0.0012 18.5 0.3 6.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EXF79595.1 - 1.8e-06 27.8 18.6 0.21 11.8 0.1 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 EXF79595.1 - 4.8e-05 22.8 0.1 5.8 6.5 0.0 3.8 3 0 0 3 3 3 3 Kelch motif SKG6 PF08693.5 EXF79595.1 - 0.11 11.7 1.0 0.21 10.9 0.7 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Kelch_2 PF07646.10 EXF79595.1 - 0.15 11.8 13.4 0.8 9.5 0.0 5.9 7 0 0 7 7 7 0 Kelch motif VSP PF03302.8 EXF79595.1 - 0.16 10.5 1.3 0.24 10.0 0.9 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein Glyco_hydro_16 PF00722.16 EXF79596.1 - 6.5e-12 45.1 1.8 9.1e-12 44.6 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Ecl1 PF12855.2 EXF79597.1 - 3.5e-12 45.4 2.1 6.2e-12 44.6 1.5 1.3 1 0 0 1 1 1 1 Life-span regulatory factor DUF581 PF04570.9 EXF79597.1 - 0.00042 19.5 3.3 0.00079 18.6 2.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF581) zf-MYND PF01753.13 EXF79597.1 - 0.1 12.5 1.6 0.18 11.6 1.1 1.4 1 0 0 1 1 1 0 MYND finger DUF329 PF03884.9 EXF79597.1 - 0.11 12.0 2.7 0.24 10.9 1.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF329) DUF3176 PF11374.3 EXF79598.1 - 6.8e-30 103.1 1.0 1.6e-29 102.0 0.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF3635 PF12330.3 EXF79599.1 - 1.8e-06 27.9 0.0 1.5e-05 24.9 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3635) DUF1682 PF07946.9 EXF79600.1 - 8.2e-107 356.7 0.3 9.6e-107 356.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) DUF2140 PF09911.4 EXF79600.1 - 0.16 11.0 0.0 0.16 11.0 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) Glyco_hydro_3 PF00933.16 EXF79601.1 - 1.3e-76 257.4 0.0 2.1e-76 256.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF79601.1 - 1.5e-70 237.2 0.1 2.4e-70 236.5 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF79601.1 - 3.2e-24 84.6 1.1 7.7e-24 83.4 0.3 2.0 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 EXF79601.1 - 4.1e-18 65.4 0.0 7.9e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 PA14 domain DUF2306 PF10067.4 EXF79602.1 - 1.1e-09 38.3 8.9 1.1e-09 38.3 6.2 1.9 3 0 0 3 3 3 1 Predicted membrane protein (DUF2306) DUF420 PF04238.7 EXF79602.1 - 0.16 11.9 6.2 0.13 12.1 1.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF420) S1FA PF04689.8 EXF79602.1 - 0.23 11.3 0.8 4.6 7.1 0.3 3.0 3 0 0 3 3 3 0 DNA binding protein S1FA PrgI PF12666.2 EXF79602.1 - 2.8 8.1 9.5 0.1 12.7 1.1 2.4 2 2 0 2 2 2 0 PrgI family protein FTA4 PF13093.1 EXF79603.1 - 7.8e-53 179.0 0.3 9e-53 178.8 0.2 1.1 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Sds3 PF08598.6 EXF79603.1 - 0.096 12.1 0.2 0.16 11.5 0.2 1.3 1 0 0 1 1 1 0 Sds3-like Peptidase_C2 PF00648.16 EXF79604.1 - 2.7e-57 194.0 1.8 7.4e-39 133.5 0.6 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease VIT1 PF01988.14 EXF79604.1 - 0.084 12.3 2.1 0.15 11.5 1.5 1.4 1 0 0 1 1 1 0 VIT family DUF3987 PF13148.1 EXF79604.1 - 2.3 6.7 11.2 8 4.9 8.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) zf-CCHC PF00098.18 EXF79605.1 - 6e-44 145.9 58.3 4e-08 32.7 2.0 7.2 7 0 0 7 7 7 7 Zinc knuckle zf-CCHC_4 PF14392.1 EXF79605.1 - 8.3e-10 38.1 41.0 0.074 12.7 0.7 7.1 7 0 0 7 7 7 6 Zinc knuckle zf-CCHC_3 PF13917.1 EXF79605.1 - 6.2e-06 25.8 41.9 0.041 13.6 0.1 6.9 4 2 2 6 6 6 5 Zinc knuckle zf-CCHC_2 PF13696.1 EXF79605.1 - 0.08 12.4 0.4 0.08 12.4 0.3 7.1 4 2 3 7 7 7 0 Zinc knuckle zf-CCHC_6 PF15288.1 EXF79605.1 - 0.12 12.1 0.3 0.12 12.1 0.2 6.9 6 1 1 7 7 7 0 Zinc knuckle Prp31_C PF09785.4 EXF79606.1 - 3.1e-44 150.3 1.5 6.3e-44 149.3 1.0 1.5 1 0 0 1 1 1 1 Prp31 C terminal domain Nop PF01798.13 EXF79606.1 - 2.4e-38 130.7 0.1 5.4e-38 129.6 0.1 1.6 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EXF79606.1 - 1e-20 73.2 0.1 1.8e-20 72.4 0.1 1.4 1 0 0 1 1 1 1 NOSIC (NUC001) domain HAT PF02184.11 EXF79607.1 - 2.2e-23 81.6 72.5 3e-12 46.0 2.0 12.9 15 0 0 15 15 15 5 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 EXF79607.1 - 1.9e-19 68.4 22.8 0.00051 20.4 0.0 10.4 8 2 4 12 12 10 5 Tetratricopeptide repeat TPR_19 PF14559.1 EXF79607.1 - 9e-18 64.3 1.5 8.9e-05 22.7 0.0 6.6 7 0 0 7 7 6 3 Tetratricopeptide repeat Suf PF05843.9 EXF79607.1 - 1.3e-15 57.9 18.9 1.7e-05 24.7 0.0 6.3 3 1 3 6 6 6 4 Suppressor of forked protein (Suf) TPR_16 PF13432.1 EXF79607.1 - 2.9e-14 53.2 21.4 0.0051 17.4 0.1 8.2 8 2 1 9 9 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 EXF79607.1 - 2.6e-05 23.7 16.9 0.23 11.4 0.0 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat U3_assoc_6 PF08640.6 EXF79607.1 - 2.9e-05 23.7 27.3 0.014 15.1 0.7 7.2 5 2 2 7 7 7 2 U3 small nucleolar RNA-associated protein 6 TPR_12 PF13424.1 EXF79607.1 - 0.00018 21.3 18.7 0.048 13.6 0.0 7.4 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 EXF79607.1 - 0.0042 16.7 3.1 41 4.2 0.0 5.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 EXF79607.1 - 0.013 15.3 5.4 0.59 10.0 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EXF79607.1 - 0.021 14.4 13.0 0.91 9.2 0.0 5.5 5 1 2 7 7 7 0 TPR repeat TPR_1 PF00515.23 EXF79607.1 - 0.048 13.2 2.9 22 4.8 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EXF79607.1 - 0.053 13.3 8.5 5.8 6.8 0.2 5.6 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat NRDE-2 PF08424.5 EXF79607.1 - 0.11 11.4 30.8 0.62 8.8 2.0 6.0 3 3 3 6 6 6 0 NRDE-2, necessary for RNA interference TPR_17 PF13431.1 EXF79607.1 - 0.11 12.6 7.1 14 6.1 0.0 6.0 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.1 EXF79607.1 - 0.44 11.1 27.3 1.6 9.3 0.0 8.8 10 0 0 10 10 9 0 Tetratricopeptide repeat La PF05383.12 EXF79610.1 - 2.4e-16 59.2 0.0 4.1e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 La domain Got1 PF04178.7 EXF79611.1 - 7.2e-31 106.7 16.1 9.7e-31 106.3 11.2 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family Peptidase_M50 PF02163.17 EXF79611.1 - 0.02 13.8 0.0 0.027 13.4 0.0 1.4 1 1 0 1 1 1 0 Peptidase family M50 HLH PF00010.21 EXF79612.1 - 1.7e-12 46.8 0.0 5.1e-12 45.3 0.0 1.8 1 1 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF3734 PF12536.3 EXF79612.1 - 0.015 15.3 1.0 0.63 10.1 0.1 2.4 2 0 0 2 2 2 0 Patatin phospholipase NPR3 PF03666.8 EXF79613.1 - 2.5e-134 448.2 0.3 3.3e-134 447.8 0.2 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 NPR2 PF06218.6 EXF79613.1 - 0.018 13.7 0.2 0.031 12.9 0.1 1.3 1 0 0 1 1 1 0 Nitrogen permease regulator 2 ATHILA PF03078.10 EXF79613.1 - 1.1 7.7 7.8 2.1 6.8 5.4 1.3 1 0 0 1 1 1 0 ATHILA ORF-1 family Choline_kinase PF01633.15 EXF79614.1 - 3.5e-53 180.2 0.0 2.5e-52 177.5 0.0 2.0 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EXF79614.1 - 2.9e-12 46.8 1.2 8.6e-12 45.2 0.0 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EXF79614.1 - 0.0032 16.6 0.0 0.0058 15.8 0.0 1.4 1 0 0 1 1 1 1 Ecdysteroid kinase MtrG PF04210.8 EXF79614.1 - 0.12 12.0 0.0 0.33 10.6 0.0 1.7 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G zf-C2H2_4 PF13894.1 EXF79616.1 - 0.058 13.7 0.0 0.058 13.7 0.0 6.9 7 0 0 7 7 7 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF79616.1 - 4.3 7.8 25.4 1.9 8.9 0.0 5.9 6 0 0 6 6 6 0 Zinc finger, C2H2 type Methyltransf_11 PF08241.7 EXF79617.1 - 1.3e-11 44.8 0.0 4.5e-11 43.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF79617.1 - 0.00022 20.9 0.0 0.00091 18.9 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF79617.1 - 0.037 14.5 0.0 0.1 13.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.13 EXF79617.1 - 0.049 12.7 0.0 0.084 11.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 EXF79617.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_25 PF13649.1 EXF79617.1 - 0.16 12.3 0.0 0.38 11.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain SUI1 PF01253.17 EXF79619.1 - 2.6e-22 78.4 0.2 6.8e-22 77.0 0.1 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 TnpV PF14198.1 EXF79619.1 - 0.0049 16.7 0.1 0.0095 15.8 0.1 1.4 1 0 0 1 1 1 1 Transposon-encoded protein TnpV Nbl1_Borealin_N PF10444.4 EXF79620.1 - 2.2e-19 68.5 6.2 3.6e-19 67.8 4.3 1.4 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal VWA_2 PF13519.1 EXF79621.1 - 6.2e-15 55.7 0.1 8.6e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ssl1 PF04056.9 EXF79621.1 - 3.2e-07 30.1 0.0 4.4e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like VWA PF00092.23 EXF79621.1 - 7.4e-07 29.0 0.6 1.1e-06 28.4 0.4 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.15 EXF79621.1 - 0.001 18.4 1.1 0.0034 16.8 0.8 2.0 1 0 0 1 1 1 1 Ubiquitin interaction motif Serglycin PF04360.7 EXF79621.1 - 0.037 13.7 1.3 0.067 12.9 0.9 1.5 1 0 0 1 1 1 0 Serglycin DUF243 PF03103.12 EXF79621.1 - 0.05 13.7 0.1 0.12 12.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF243) Sybindin PF04099.7 EXF79622.1 - 1e-52 177.6 0.0 1.2e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EXF79622.1 - 3.3e-08 33.4 0.1 6.3e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region RNA_pol_Rpb4 PF03874.11 EXF79623.1 - 2.8e-28 98.2 4.9 3.4e-28 97.9 3.4 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF2312 PF10073.4 EXF79623.1 - 0.087 12.1 1.3 0.43 9.9 0.2 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) Plasmodium_Vir PF05795.6 EXF79624.1 - 0.035 13.3 0.1 0.052 12.7 0.1 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein EphA2_TM PF14575.1 EXF79624.1 - 0.056 13.8 0.3 1.7 9.1 0.0 2.5 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain IncA PF04156.9 EXF79624.1 - 0.17 11.4 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 IncA protein CPL PF08144.6 EXF79625.1 - 7.2e-22 77.8 0.0 3.4e-21 75.6 0.0 2.2 2 0 0 2 2 2 1 CPL (NUC119) domain PUF PF00806.14 EXF79625.1 - 0.068 12.6 0.0 3.2 7.4 0.0 3.6 5 0 0 5 5 5 0 Pumilio-family RNA binding repeat Meckelin PF09773.4 EXF79625.1 - 0.16 9.7 0.0 0.24 9.1 0.0 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) PAP_central PF04928.12 EXF79625.1 - 0.47 9.2 4.3 0.95 8.2 0.1 2.5 3 0 0 3 3 3 0 Poly(A) polymerase central domain RWD PF05773.17 EXF79626.1 - 2.1e-22 79.1 0.2 3.9e-22 78.2 0.1 1.5 1 0 0 1 1 1 1 RWD domain Bap31 PF05529.7 EXF79626.1 - 0.45 9.9 3.7 0.64 9.4 2.6 1.3 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF3886 PF13025.1 EXF79626.1 - 2.6 8.0 19.5 0.44 10.5 5.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) DUF3323 PF11796.3 EXF79626.1 - 3.8 6.7 10.3 8.3 5.6 7.1 1.5 1 1 0 1 1 1 0 Protein of unknown function N-terminus (DUF3323) TPR_12 PF13424.1 EXF79627.1 - 5.4e-11 42.2 6.2 1.2e-06 28.3 0.6 4.0 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EXF79627.1 - 2.1e-10 40.7 8.8 0.0011 19.2 0.3 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EXF79627.1 - 4.9e-10 38.8 0.1 0.0011 18.5 0.2 3.1 3 1 0 3 3 3 2 TPR repeat TPR_2 PF07719.12 EXF79627.1 - 2.8e-09 36.2 12.1 2.4e-06 27.0 0.0 5.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 EXF79627.1 - 8.3e-09 34.6 0.4 7.3e-05 22.2 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EXF79627.1 - 3.2e-08 34.0 12.1 0.0065 17.1 0.4 4.3 4 1 0 4 4 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EXF79627.1 - 1.9e-07 30.3 0.6 0.00017 21.1 0.0 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_14 PF13428.1 EXF79627.1 - 4.5e-07 29.9 11.7 0.0045 17.5 0.2 5.6 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EXF79627.1 - 3.4e-06 26.4 0.2 0.031 14.0 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EXF79627.1 - 0.00011 22.3 0.1 0.2 11.8 0.1 3.3 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EXF79627.1 - 0.00083 19.2 2.2 1.3 9.0 0.3 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EXF79627.1 - 0.0009 19.2 0.1 49 4.4 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EXF79627.1 - 0.0031 17.8 4.3 3.1 8.4 0.0 5.4 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 EXF79627.1 - 0.093 12.5 3.8 12 5.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.12 EXF79627.1 - 3.9 7.7 9.2 2.1 8.6 0.2 3.3 3 1 0 3 3 3 0 Bacterial transcriptional activator domain TRP PF06011.7 EXF79628.1 - 3.4e-88 296.1 26.9 9.1e-88 294.7 18.7 1.6 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EXF79628.1 - 5.3e-22 78.3 0.1 8.8e-22 77.6 0.1 1.3 1 0 0 1 1 1 1 ML-like domain HATPase_c_3 PF13589.1 EXF79629.1 - 1.1e-13 51.0 0.1 2.4e-13 49.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EXF79629.1 - 9.9e-10 38.1 0.1 2.2e-09 36.9 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 EXF79629.1 - 0.00017 20.9 0.0 0.00045 19.6 0.0 1.7 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain DMRL_synthase PF00885.14 EXF79630.1 - 1.2e-45 154.6 0.1 3.5e-27 94.8 0.0 2.0 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase Formyl_trans_N PF00551.14 EXF79632.1 - 1.1e-36 126.1 0.0 1.3e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase MannoseP_isomer PF01050.13 EXF79632.1 - 0.045 13.3 0.0 0.087 12.4 0.0 1.5 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase Asp_Glu_race PF01177.17 EXF79632.1 - 0.075 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase Glyco_trans_4_4 PF13579.1 EXF79632.1 - 0.08 13.0 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Cation_efflux PF01545.16 EXF79633.1 - 7.3e-35 120.4 12.1 1.1e-34 119.8 8.4 1.2 1 0 0 1 1 1 1 Cation efflux family PI3_PI4_kinase PF00454.22 EXF79634.1 - 8.2e-41 139.9 0.0 2.5e-40 138.4 0.0 1.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EXF79634.1 - 2e-21 76.0 0.0 5.4e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Flu_NS2 PF00601.14 EXF79634.1 - 0.014 15.5 0.6 1.1 9.4 0.0 2.9 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) Proteasome PF00227.21 EXF79635.1 - 2.2e-28 98.8 0.3 8e-28 97.0 0.2 1.9 2 1 0 2 2 2 1 Proteasome subunit YTH PF04146.10 EXF79636.1 - 2.3e-56 189.2 0.0 3.4e-56 188.7 0.0 1.2 1 0 0 1 1 1 1 YT521-B-like domain RRM_6 PF14259.1 EXF79636.1 - 0.0019 18.1 0.0 0.0058 16.5 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EXF79636.1 - 0.0078 15.8 0.0 0.02 14.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF79636.1 - 0.077 12.8 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HSP20 PF00011.16 EXF79637.1 - 9.6e-16 57.5 0.0 1.3e-10 40.9 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family SOG2 PF10428.4 EXF79637.1 - 0.054 12.1 0.4 9.8 4.7 1.2 2.0 2 0 0 2 2 2 0 RAM signalling pathway protein Pneumo_att_G PF05539.6 EXF79637.1 - 1.1 8.5 6.8 1.5 8.1 4.7 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Rad51 PF08423.6 EXF79638.1 - 1.3e-137 456.8 0.0 1.6e-137 456.4 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EXF79638.1 - 7.5e-13 48.3 0.0 1.1e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain HHH_5 PF14520.1 EXF79638.1 - 3.8e-08 33.3 0.4 1.3e-07 31.6 0.1 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain RecA PF00154.16 EXF79638.1 - 7.7e-08 31.7 0.0 9.9e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein KaiC PF06745.8 EXF79638.1 - 2.1e-06 27.0 0.0 3.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.10 EXF79638.1 - 0.05 12.4 0.0 0.097 11.5 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PAXNEB PF05625.6 EXF79638.1 - 0.13 11.0 0.0 0.25 10.1 0.0 1.4 1 0 0 1 1 1 0 PAXNEB protein Nup160 PF11715.3 EXF79639.1 - 8.9e-136 453.2 1.7 1.1e-135 452.8 1.2 1.1 1 0 0 1 1 1 1 Nucleoporin Nup120/160 TPR_2 PF07719.12 EXF79639.1 - 0.69 9.9 3.0 0.53 10.3 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat peroxidase PF00141.18 EXF79641.1 - 2.1e-19 69.9 0.3 3.4e-19 69.2 0.2 1.3 1 0 0 1 1 1 1 Peroxidase FAD_binding_3 PF01494.14 EXF79642.1 - 4.2e-73 246.4 0.0 5.1e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EXF79642.1 - 6.1e-35 120.3 0.0 9.4e-35 119.7 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox_2 PF07992.9 EXF79642.1 - 1.3e-05 25.1 0.0 4.1e-05 23.5 0.0 1.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF79642.1 - 3.4e-05 24.1 0.0 0.0093 16.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF79642.1 - 5.2e-05 21.9 0.4 0.00011 20.7 0.1 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EXF79642.1 - 0.0006 19.7 0.1 0.0015 18.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EXF79642.1 - 0.0026 16.7 0.1 0.004 16.1 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EXF79642.1 - 0.0051 15.4 0.0 0.0078 14.8 0.0 1.2 1 0 0 1 1 1 1 Tryptophan halogenase Thi4 PF01946.12 EXF79642.1 - 0.0052 15.9 0.0 0.009 15.1 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EXF79642.1 - 0.0055 16.7 1.0 0.016 15.3 0.7 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF79642.1 - 0.0078 15.1 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A DAO PF01266.19 EXF79642.1 - 0.014 14.3 0.1 0.41 9.5 0.1 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase XdhC_C PF13478.1 EXF79642.1 - 0.12 12.7 0.0 0.24 11.7 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain 3HCDH_N PF02737.13 EXF79642.1 - 0.21 11.2 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EXF79642.1 - 0.24 10.7 0.0 0.39 10.0 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TPR_12 PF13424.1 EXF79644.1 - 1.9e-24 85.3 1.3 2.1e-18 66.0 0.5 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.1 EXF79644.1 - 1.4e-23 82.0 3.1 4.5e-10 39.1 0.3 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.1 EXF79644.1 - 1.8e-13 49.1 10.9 7.4e-05 22.2 0.3 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EXF79644.1 - 8.1e-13 47.3 6.7 0.00034 20.0 0.2 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EXF79644.1 - 8e-09 35.0 6.7 2.2e-07 30.4 0.6 2.8 2 1 1 3 3 2 2 TPR repeat TPR_2 PF07719.12 EXF79644.1 - 1.1e-08 34.2 6.4 0.0083 15.9 0.3 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EXF79644.1 - 2.8e-08 32.9 6.2 0.21 11.4 0.1 4.0 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EXF79644.1 - 1.4e-07 31.4 1.0 0.021 15.4 0.3 4.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EXF79644.1 - 3e-06 27.7 1.3 6.3e-05 23.5 0.5 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EXF79644.1 - 7.8e-05 22.5 0.5 0.67 10.3 0.0 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EXF79644.1 - 8.1e-05 22.8 1.9 0.0024 18.1 0.3 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_4 PF07721.9 EXF79644.1 - 0.00082 19.5 0.0 0.11 13.0 0.0 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EXF79644.1 - 0.0046 17.0 0.3 0.014 15.5 0.2 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.4 EXF79644.1 - 0.018 14.4 0.5 0.018 14.4 0.3 2.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-C2H2_4 PF13894.1 EXF79644.1 - 0.02 15.1 7.9 0.024 14.9 0.2 3.5 3 0 0 3 3 2 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF79644.1 - 0.035 14.4 0.5 0.035 14.4 0.3 3.2 4 0 0 4 4 2 0 Zinc finger, C2H2 type TPR_3 PF07720.7 EXF79644.1 - 0.039 13.7 0.4 0.039 13.7 0.3 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EXF79644.1 - 0.14 12.6 11.3 0.82 10.2 0.6 4.4 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF629 PF04780.7 EXF79644.1 - 0.67 8.4 5.6 5.7 5.3 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF629) SOCS_box PF07525.11 EXF79646.1 - 0.034 13.9 0.1 0.081 12.8 0.0 1.6 2 0 0 2 2 2 0 SOCS box FRQ PF09421.5 EXF79647.1 - 0 1093.0 54.6 0 1092.7 37.8 1.0 1 0 0 1 1 1 1 Frequency clock protein PTS_2-RNA PF01885.11 EXF79647.1 - 0.018 14.3 0.2 0.085 12.1 0.0 2.0 2 0 0 2 2 2 0 RNA 2'-phosphotransferase, Tpt1 / KptA family ketoacyl-synt PF00109.21 EXF79648.1 - 2.5e-73 246.6 0.1 1e-72 244.6 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EXF79648.1 - 3.7e-35 120.3 0.1 7.3e-35 119.3 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.16 EXF79648.1 - 3.7e-25 88.9 0.0 6.3e-25 88.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PP-binding PF00550.20 EXF79648.1 - 4.9e-22 77.9 8.1 6.4e-13 48.7 0.8 3.1 3 0 0 3 3 3 2 Phosphopantetheine attachment site PS-DH PF14765.1 EXF79648.1 - 6.4e-21 74.7 0.1 4.8e-20 71.9 0.0 2.1 1 1 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 EXF79648.1 - 1.4e-15 57.5 0.0 4.1e-15 56.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_3 PF07859.8 EXF79648.1 - 2.3e-14 53.4 0.0 3.5e-12 46.3 0.0 2.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Methyltransf_23 PF13489.1 EXF79648.1 - 7.6e-11 41.9 0.0 1.9e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_5 PF12695.2 EXF79648.1 - 2e-08 34.1 0.4 5.1e-07 29.5 0.0 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Methyltransf_31 PF13847.1 EXF79648.1 - 8.4e-08 31.9 0.0 1.7e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF79648.1 - 1e-07 32.3 0.0 3.1e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Peptidase_S9 PF00326.16 EXF79648.1 - 3.9e-07 29.5 0.0 0.0024 17.1 0.0 2.6 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EXF79648.1 - 7.1e-06 26.0 1.5 7.1e-06 26.0 1.0 2.0 2 0 0 2 2 2 1 Alpha/beta hydrolase family Methyltransf_18 PF12847.2 EXF79648.1 - 8.2e-06 26.3 0.0 4.5e-05 23.9 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Thiolase_N PF00108.18 EXF79648.1 - 7.7e-05 21.7 0.1 0.0058 15.6 0.0 2.3 2 0 0 2 2 2 1 Thiolase, N-terminal domain PP-binding_2 PF14573.1 EXF79648.1 - 0.00022 21.2 0.3 0.42 10.6 0.0 2.7 2 0 0 2 2 2 2 Acyl-carrier Methyltransf_26 PF13659.1 EXF79648.1 - 0.0039 17.1 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Thioesterase PF00975.15 EXF79648.1 - 0.017 15.3 0.0 0.29 11.3 0.0 2.4 2 0 0 2 2 2 0 Thioesterase domain DLH PF01738.13 EXF79648.1 - 0.03 13.6 0.0 7.5 5.7 0.0 2.4 2 0 0 2 2 2 0 Dienelactone hydrolase family Methyltransf_16 PF10294.4 EXF79648.1 - 0.041 13.3 0.0 0.13 11.7 0.0 1.8 1 1 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 EXF79648.1 - 0.19 10.8 0.0 0.36 9.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family p450 PF00067.17 EXF79649.1 - 6.8e-66 222.6 0.0 8.2e-66 222.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Trp_DMAT PF11991.3 EXF79650.1 - 4.2e-87 292.7 0.0 1.4e-86 290.9 0.0 1.7 2 0 0 2 2 2 1 Tryptophan dimethylallyltransferase Fungal_trans_2 PF11951.3 EXF79651.1 - 2.7e-08 32.8 0.8 5.6e-06 25.1 0.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain FAD_binding_4 PF01565.18 EXF79652.1 - 4.5e-21 74.7 0.3 9.9e-21 73.6 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF79652.1 - 0.00066 19.5 0.3 0.0018 18.1 0.2 1.8 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.20 EXF79653.1 - 6.1e-13 49.0 1.3 7.3e-13 48.7 0.9 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF79653.1 - 2.4e-07 30.5 1.5 3.5e-07 30.0 1.0 1.3 1 1 0 1 1 1 1 KR domain ThiF PF00899.16 EXF79653.1 - 4.6e-06 26.5 0.2 6.4e-06 26.0 0.1 1.2 1 0 0 1 1 1 1 ThiF family Eno-Rase_NADH_b PF12242.3 EXF79653.1 - 0.0048 16.6 1.6 0.0094 15.7 1.1 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Ldh_1_N PF00056.18 EXF79653.1 - 0.0082 15.9 0.2 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EXF79653.1 - 0.016 14.1 0.0 0.02 13.8 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EXF79653.1 - 0.039 12.8 0.1 0.29 9.9 0.0 2.0 2 0 0 2 2 2 0 RmlD substrate binding domain Epimerase PF01370.16 EXF79653.1 - 0.053 12.9 0.2 0.073 12.4 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EXF79654.1 - 1e-19 71.0 0.3 1.8e-19 70.2 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF79654.1 - 4e-16 59.2 0.1 5.9e-16 58.6 0.1 1.3 1 0 0 1 1 1 1 KR domain Myb_DNA-bind_6 PF13921.1 EXF79655.1 - 6e-10 39.0 2.0 2.2e-06 27.6 0.0 3.3 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EXF79655.1 - 1.3e-08 34.7 3.7 4.5e-07 29.8 0.1 3.2 3 0 0 3 3 3 1 Myb-like DNA-binding domain Rap1_C PF11626.3 EXF79655.1 - 0.0061 16.4 0.8 1.4 8.8 0.1 2.4 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Alpha_adaptin_C PF02296.11 EXF79655.1 - 0.13 12.1 0.1 12 5.8 0.0 2.6 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain AMP-binding PF00501.23 EXF79656.1 - 1.6e-32 112.4 0.0 3.4e-32 111.3 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EXF79656.1 - 9.9e-29 99.9 0.0 1.5e-28 99.3 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EXF79656.1 - 1.3e-08 34.5 0.0 3.5e-08 33.1 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EXF79656.1 - 0.0002 21.2 0.8 0.11 12.4 0.0 3.2 3 0 0 3 3 3 2 short chain dehydrogenase FB_lectin PF07367.6 EXF79656.1 - 0.0034 16.9 0.0 2 8.0 0.0 2.4 2 0 0 2 2 2 2 Fungal fruit body lectin KR PF08659.5 EXF79656.1 - 0.005 16.5 0.1 0.14 11.8 0.0 2.6 2 0 0 2 2 2 1 KR domain PP-binding PF00550.20 EXF79656.1 - 0.0095 16.1 0.2 0.046 13.9 0.1 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site RmlD_sub_bind PF04321.12 EXF79656.1 - 0.014 14.3 0.0 0.068 12.0 0.0 1.9 2 0 0 2 2 2 0 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EXF79656.1 - 0.23 10.3 0.0 0.58 8.9 0.0 1.6 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein ApbA PF02558.11 EXF79658.1 - 4.5e-22 78.1 0.0 6.7e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ApbA_C PF08546.6 EXF79658.1 - 1.7e-21 76.5 0.0 2.5e-21 75.9 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal EF-hand_1 PF00036.27 EXF79659.1 - 1.3e-25 86.6 5.3 5.8e-06 25.2 0.0 5.4 5 1 0 5 5 5 5 EF hand EF-hand_7 PF13499.1 EXF79659.1 - 3.3e-24 84.8 2.0 8.1e-09 35.4 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EXF79659.1 - 1e-20 71.6 5.3 0.00074 19.1 0.4 5.3 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.1 EXF79659.1 - 5.4e-19 67.5 8.3 2.8e-09 36.4 0.0 4.7 2 2 3 5 5 5 4 EF-hand domain pair EF-hand_5 PF13202.1 EXF79659.1 - 8.1e-17 59.7 6.9 0.0007 18.8 0.0 4.6 4 0 0 4 4 4 4 EF hand ChaC PF04752.7 EXF79660.1 - 5.8e-36 124.1 0.0 8.3e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 ChaC-like protein RRM_1 PF00076.17 EXF79661.1 - 5.3e-23 80.4 0.0 6.9e-23 80.0 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF79661.1 - 2.4e-15 56.2 0.0 3.1e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF79661.1 - 3.6e-09 36.3 0.0 4.7e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EXF79661.1 - 0.13 12.0 0.1 0.2 11.5 0.1 1.3 1 0 0 1 1 1 0 RNA binding motif COX4 PF02936.9 EXF79662.1 - 2.6e-50 169.8 0.0 2.9e-50 169.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Alpha-amylase_C PF02806.13 EXF79663.1 - 2.3e-25 88.5 0.2 1.2e-24 86.3 0.1 2.2 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EXF79663.1 - 1.6e-18 67.2 0.2 9.1e-14 51.5 0.0 2.7 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EXF79663.1 - 3.2e-17 62.3 0.0 7.5e-17 61.1 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) AAA_2 PF07724.9 EXF79664.1 - 9.9e-32 110.1 0.0 2e-31 109.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EXF79664.1 - 2.8e-12 46.9 0.0 5.5e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EXF79664.1 - 2.1e-09 37.1 0.0 4.3e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EXF79664.1 - 6.3e-08 32.4 0.0 1.3e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EXF79664.1 - 0.00028 21.0 0.2 0.0036 17.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EXF79664.1 - 0.00036 20.4 0.0 0.0008 19.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EXF79664.1 - 0.00048 20.9 0.4 0.0013 19.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain MCM PF00493.18 EXF79664.1 - 0.0021 16.9 0.0 0.0043 15.9 0.0 1.4 1 0 0 1 1 1 1 MCM2/3/5 family AAA_16 PF13191.1 EXF79664.1 - 0.0023 17.9 0.0 0.04 13.9 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.12 EXF79664.1 - 0.0029 17.0 0.0 0.0057 16.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 EXF79664.1 - 0.058 13.7 1.7 0.068 13.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain T2SE PF00437.15 EXF79664.1 - 0.075 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein ResIII PF04851.10 EXF79664.1 - 0.1 12.4 0.1 0.64 9.8 0.0 2.3 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.22 EXF79664.1 - 0.11 12.7 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 ABC transporter RPT PF13446.1 EXF79664.1 - 0.17 11.2 0.1 0.4 10.1 0.1 1.5 1 0 0 1 1 1 0 A repeated domain in UCH-protein ATP-synt_ab PF00006.20 EXF79665.1 - 6e-62 208.9 0.0 9.1e-62 208.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EXF79665.1 - 4e-25 88.4 1.5 5.6e-25 88.0 0.4 1.7 2 0 0 2 2 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EXF79665.1 - 1.2e-24 86.2 0.2 3.3e-24 84.8 0.1 1.8 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA PF00004.24 EXF79665.1 - 0.0065 16.6 0.1 0.43 10.7 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EXF79665.1 - 0.007 15.7 0.1 0.048 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EXF79665.1 - 0.01 15.5 0.0 0.026 14.2 0.0 1.6 2 0 0 2 2 2 0 Archaeal ATPase MobB PF03205.9 EXF79665.1 - 0.013 15.2 0.1 1.1 9.0 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B DUF258 PF03193.11 EXF79665.1 - 0.014 14.5 0.1 0.026 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 KaiC PF06745.8 EXF79665.1 - 0.019 14.1 0.1 0.032 13.3 0.1 1.4 1 0 0 1 1 1 0 KaiC NACHT PF05729.7 EXF79665.1 - 0.026 14.1 0.1 0.07 12.7 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.1 EXF79665.1 - 0.047 13.8 0.1 0.19 11.8 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EXF79665.1 - 0.049 13.6 0.3 0.32 10.9 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain RNA_helicase PF00910.17 EXF79665.1 - 0.065 13.4 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase NB-ARC PF00931.17 EXF79665.1 - 0.097 11.5 0.6 0.61 8.8 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain DUF4050 PF13259.1 EXF79666.1 - 6.8e-34 116.4 0.2 1.5e-33 115.2 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4050) PAPA-1 PF04795.7 EXF79667.1 - 5.3e-17 62.2 7.2 2e-10 41.2 0.0 3.4 4 0 0 4 4 4 2 PAPA-1-like conserved region Pex14_N PF04695.8 EXF79668.1 - 6.5e-24 84.5 1.4 6.5e-24 84.5 1.0 2.8 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Helicase_IV_N PF12462.3 EXF79668.1 - 0.051 13.2 0.3 13 5.3 0.3 2.4 2 0 0 2 2 2 0 DNA helicase IV / RNA helicase N terminal Ribosomal_60s PF00428.14 EXF79668.1 - 4.2 7.8 13.8 0.25 11.7 2.7 2.9 2 1 0 2 2 2 0 60s Acidic ribosomal protein Chromo PF00385.19 EXF79669.1 - 1.4e-08 34.3 0.9 3.8e-08 32.8 0.6 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ras PF00071.17 EXF79670.1 - 2.1e-63 212.5 0.2 2.5e-63 212.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EXF79670.1 - 2e-21 76.6 0.1 2.7e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EXF79670.1 - 4e-13 48.9 0.1 5e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EXF79670.1 - 3.2e-08 33.5 0.1 4.9e-08 32.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EXF79670.1 - 4.8e-05 22.8 0.1 0.00016 21.2 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EXF79670.1 - 9.9e-05 21.5 0.1 0.00017 20.8 0.1 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EXF79670.1 - 0.00013 22.1 0.1 0.00033 20.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EXF79670.1 - 0.0016 18.3 0.1 0.0034 17.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_15 PF13175.1 EXF79670.1 - 0.002 17.2 0.1 0.0023 17.0 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EXF79670.1 - 0.0027 16.9 0.1 0.0062 15.7 0.1 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SpoIIID PF12116.3 EXF79670.1 - 0.0074 16.1 0.1 0.096 12.6 0.0 2.1 2 0 0 2 2 2 1 Stage III sporulation protein D SRPRB PF09439.5 EXF79670.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 EXF79670.1 - 0.018 14.6 0.1 0.053 13.1 0.0 1.7 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 EXF79670.1 - 0.019 15.2 0.1 0.026 14.7 0.0 1.4 1 1 0 1 1 1 0 ABC transporter AAA_16 PF13191.1 EXF79670.1 - 0.023 14.6 0.3 0.046 13.7 0.2 1.7 1 1 0 1 1 1 0 AAA ATPase domain FeoB_N PF02421.13 EXF79670.1 - 0.092 12.0 0.1 0.23 10.7 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_29 PF13555.1 EXF79670.1 - 0.096 12.2 0.0 0.24 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_32 PF13654.1 EXF79670.1 - 0.12 11.0 0.1 0.89 8.1 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_5 PF07728.9 EXF79670.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Brix PF04427.13 EXF79671.1 - 2.3e-29 102.4 0.0 3.2e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Brix domain F-box PF00646.28 EXF79672.1 - 0.0012 18.4 0.0 0.0027 17.3 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EXF79672.1 - 0.0021 17.7 0.3 0.18 11.5 0.0 2.6 3 0 0 3 3 3 2 F-box-like Hist_deacetyl PF00850.14 EXF79673.1 - 2.6e-91 306.1 0.0 4e-91 305.5 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain Arb2 PF09757.4 EXF79673.1 - 1.7e-35 122.0 0.1 3.1e-35 121.2 0.1 1.4 1 0 0 1 1 1 1 Arb2 domain Fzo_mitofusin PF04799.8 EXF79674.1 - 0.23 10.8 0.5 0.34 10.2 0.4 1.2 1 0 0 1 1 1 0 fzo-like conserved region VEFS-Box PF09733.4 EXF79676.1 - 3.6e-05 23.4 0.0 7.1e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 VEFS-Box of polycomb protein PHD PF00628.24 EXF79676.1 - 8.2e-05 22.2 3.7 8.2e-05 22.2 2.6 2.0 3 0 0 3 3 3 1 PHD-finger DUF382 PF04037.8 EXF79677.1 - 1.4e-61 206.0 0.7 4.6e-61 204.3 0.5 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF382) PSP PF04046.11 EXF79677.1 - 4.3e-19 67.6 6.0 8.5e-19 66.6 4.2 1.5 1 0 0 1 1 1 1 PSP TPT PF03151.11 EXF79678.1 - 1.2e-39 135.3 2.2 1.2e-39 135.3 1.5 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.6 EXF79678.1 - 2.8e-10 39.6 13.9 9.1e-10 37.9 9.6 1.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EXF79678.1 - 2e-07 31.0 28.4 0.0018 18.2 6.9 3.2 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EXF79678.1 - 0.0048 16.0 1.1 0.44 9.5 0.0 2.4 2 1 0 2 2 2 2 Nucleotide-sugar transporter Multi_Drug_Res PF00893.14 EXF79678.1 - 2.5 8.6 10.2 2.6 8.5 0.3 3.7 3 1 1 4 4 4 0 Small Multidrug Resistance protein TcpE PF12648.2 EXF79678.1 - 6.2 7.0 8.0 2.5 8.2 0.1 2.8 2 0 0 2 2 2 0 TcpE family ORC5_C PF14630.1 EXF79679.1 - 8.9e-79 264.7 0.0 3.3e-78 262.8 0.0 1.9 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.1 EXF79679.1 - 1.8e-15 57.4 0.2 3.9e-15 56.3 0.0 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EXF79679.1 - 0.0046 17.0 0.0 0.011 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EXF79679.1 - 0.023 14.1 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.7 EXF79679.1 - 0.047 13.3 0.0 0.1 12.2 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DUF815 PF05673.8 EXF79679.1 - 0.084 11.7 0.0 0.21 10.5 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 EXF79679.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase Septin PF00735.13 EXF79679.1 - 0.2 10.6 0.0 0.29 10.0 0.0 1.2 1 0 0 1 1 1 0 Septin Zn_clus PF00172.13 EXF79680.1 - 1.7e-07 31.0 12.0 2.6e-07 30.4 8.3 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF79680.1 - 0.0096 14.5 0.0 0.014 14.0 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain AMP-binding PF00501.23 EXF79681.1 - 5.6e-89 298.4 0.0 1e-82 277.8 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme Condensation PF00668.15 EXF79681.1 - 1.7e-57 194.5 0.0 1.2e-34 119.5 0.0 2.8 3 0 0 3 3 3 2 Condensation domain PP-binding PF00550.20 EXF79681.1 - 3.5e-26 91.2 0.3 6.6e-12 45.5 0.0 3.1 3 0 0 3 3 3 2 Phosphopantetheine attachment site zf-C2H2 PF00096.21 EXF79681.1 - 1.9e-05 24.7 38.0 0.21 12.0 0.2 7.6 7 0 0 7 7 7 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF79681.1 - 0.0032 17.6 32.3 2.1 8.8 0.0 7.3 7 0 0 7 7 7 3 C2H2-type zinc finger JmjN PF02375.12 EXF79681.1 - 0.061 12.8 0.1 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 jmjN domain zf-C2H2_2 PF12756.2 EXF79681.1 - 0.16 12.1 15.4 1.1 9.4 1.4 4.5 3 1 0 4 4 4 0 C2H2 type zinc-finger (2 copies) zf-LYAR PF08790.6 EXF79681.1 - 0.48 10.1 2.0 7.1 6.4 0.1 3.3 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2H2_jaz PF12171.3 EXF79681.1 - 1.4 9.1 8.1 1 9.5 0.6 3.6 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-DNA_Pol PF08996.5 EXF79681.1 - 2.4 7.4 5.4 15 4.8 0.2 2.4 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger CRA PF06589.6 EXF79682.1 - 0.024 13.9 0.0 0.024 13.9 0.0 2.1 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) Cortexin PF11057.3 EXF79682.1 - 0.087 12.4 2.1 0.15 11.6 0.1 2.3 2 1 0 2 2 2 0 Cortexin of kidney SLD3 PF08639.5 EXF79683.1 - 2.5e-114 382.6 0.1 4.2e-114 381.9 0.1 1.3 1 0 0 1 1 1 1 DNA replication regulator SLD3 Trs65 PF12735.2 EXF79684.1 - 1.4e-69 234.7 0.0 4.7e-69 233.0 0.0 1.7 2 0 0 2 2 2 1 TRAPP trafficking subunit Trs65 FF PF01846.14 EXF79685.1 - 2.1e-48 162.0 16.3 8.7e-14 51.2 0.2 7.1 6 1 0 6 6 6 5 FF domain WW PF00397.21 EXF79685.1 - 4.9e-19 67.8 14.8 9.1e-11 41.4 2.8 2.6 2 0 0 2 2 2 2 WW domain ABC_tran PF00005.22 EXF79686.1 - 2.2e-33 115.4 0.0 1.5e-15 57.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter RLI PF04068.10 EXF79686.1 - 2.7e-13 49.2 6.1 2.7e-13 49.2 4.2 2.0 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_21 PF13304.1 EXF79686.1 - 2.9e-13 50.4 6.2 0.082 12.8 0.0 5.2 3 2 2 5 5 5 4 AAA domain SMC_N PF02463.14 EXF79686.1 - 8.1e-12 44.8 0.3 0.00039 19.7 0.0 3.4 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EXF79686.1 - 2.5e-08 33.4 0.0 0.49 9.3 0.0 4.2 3 1 1 4 4 4 3 AAA ATPase domain AAA_17 PF13207.1 EXF79686.1 - 1.6e-06 28.9 0.2 0.039 14.7 0.0 3.0 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 EXF79686.1 - 1.1e-05 25.5 0.0 0.012 15.8 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EXF79686.1 - 1.2e-05 25.6 0.2 0.31 11.3 0.0 3.1 3 1 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EXF79686.1 - 2.5e-05 24.4 0.0 0.011 15.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EXF79686.1 - 2.8e-05 23.5 0.3 0.042 13.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain Fer4 PF00037.22 EXF79686.1 - 0.0001 21.7 1.3 0.0001 21.7 0.9 2.9 3 0 0 3 3 3 1 4Fe-4S binding domain DUF258 PF03193.11 EXF79686.1 - 0.00025 20.2 2.5 0.33 10.1 0.0 3.1 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_23 PF13476.1 EXF79686.1 - 0.00031 21.1 0.0 0.034 14.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EXF79686.1 - 0.00044 20.2 0.1 0.33 10.9 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.17 EXF79686.1 - 0.00053 20.1 0.1 0.3 11.2 0.0 2.8 2 0 0 2 2 2 1 RNA helicase UPF0079 PF02367.12 EXF79686.1 - 0.00072 19.1 0.3 0.0076 15.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 EXF79686.1 - 0.00098 18.8 1.1 0.14 11.8 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EXF79686.1 - 0.0012 18.5 0.7 0.23 11.0 0.0 2.5 2 0 0 2 2 2 1 NACHT domain Fer4_21 PF14697.1 EXF79686.1 - 0.0014 18.4 10.9 0.0026 17.5 7.6 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain VirE PF05272.6 EXF79686.1 - 0.0015 18.0 0.0 1.7 8.0 0.0 2.6 2 0 0 2 2 2 1 Virulence-associated protein E AAA_33 PF13671.1 EXF79686.1 - 0.0018 18.1 0.0 0.13 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.17 EXF79686.1 - 0.0018 17.7 2.2 0.078 12.4 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_7 PF12838.2 EXF79686.1 - 0.002 18.4 7.4 0.0095 16.3 0.3 2.5 2 0 0 2 2 2 1 4Fe-4S dicluster domain AAA_25 PF13481.1 EXF79686.1 - 0.0045 16.4 0.1 2.1 7.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EXF79686.1 - 0.0047 16.6 0.2 0.22 11.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Fer4_6 PF12837.2 EXF79686.1 - 0.0056 16.4 11.1 0.048 13.5 0.8 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain Thymidylate_kin PF02223.12 EXF79686.1 - 0.0089 15.4 0.7 2.7 7.3 0.0 3.0 3 0 0 3 3 3 1 Thymidylate kinase AAA_13 PF13166.1 EXF79686.1 - 0.011 14.2 0.0 0.011 14.2 0.0 2.2 3 0 0 3 3 2 0 AAA domain Rad17 PF03215.10 EXF79686.1 - 0.013 14.2 0.0 0.15 10.6 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_28 PF13521.1 EXF79686.1 - 0.021 14.7 0.5 1.5 8.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EXF79686.1 - 0.023 15.1 0.0 1.6 9.2 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein SbcCD_C PF13558.1 EXF79686.1 - 0.054 13.4 0.0 9 6.2 0.0 3.1 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Fer4_16 PF13484.1 EXF79686.1 - 0.066 13.9 6.1 0.068 13.9 0.1 2.6 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain NB-ARC PF00931.17 EXF79686.1 - 0.092 11.5 0.0 4.5 6.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain Fer4_8 PF13183.1 EXF79686.1 - 0.093 12.7 8.6 0.24 11.4 1.1 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain KaiC PF06745.8 EXF79686.1 - 0.14 11.2 0.0 0.37 9.8 0.0 1.7 1 0 0 1 1 1 0 KaiC T2SE PF00437.15 EXF79686.1 - 0.18 10.6 0.3 3.7 6.3 0.0 2.8 3 0 0 3 3 3 0 Type II/IV secretion system protein AAA_30 PF13604.1 EXF79686.1 - 0.22 11.1 0.1 3.6 7.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EXF79686.1 - 0.22 11.0 3.2 0.32 10.4 0.0 2.6 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.10 EXF79686.1 - 0.23 11.1 1.5 12 5.5 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_14 PF13173.1 EXF79686.1 - 0.25 11.2 2.5 18 5.2 0.0 3.6 3 2 0 3 3 2 0 AAA domain Fer4_2 PF12797.2 EXF79686.1 - 0.25 11.3 12.3 0.65 10.0 1.4 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_10 PF13237.1 EXF79686.1 - 0.51 10.1 15.3 0.048 13.4 1.0 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain AAA_24 PF13479.1 EXF79686.1 - 0.54 9.7 2.1 2.7 7.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Fer4_9 PF13187.1 EXF79686.1 - 0.55 10.5 12.9 0.097 12.9 1.5 2.4 1 1 1 2 2 2 0 4Fe-4S dicluster domain SNF2_N PF00176.18 EXF79687.1 - 2.9e-62 210.1 0.0 5.4e-62 209.2 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Chromo PF00385.19 EXF79687.1 - 1.8e-25 88.3 5.7 2.2e-14 52.8 0.6 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EXF79687.1 - 9e-15 54.3 0.0 2.8e-14 52.7 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EXF79687.1 - 9.3e-06 25.5 0.0 0.00012 21.9 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EXF79687.1 - 0.0048 17.0 0.0 0.017 15.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain SIR2 PF02146.12 EXF79688.1 - 2.2e-24 86.1 0.0 5.3e-24 84.9 0.0 1.6 1 1 0 1 1 1 1 Sir2 family Med16 PF11635.3 EXF79689.1 - 1.5e-107 360.4 0.0 2.1e-107 359.9 0.0 1.1 1 0 0 1 1 1 1 Mediator complex subunit 16 Ammonium_transp PF00909.16 EXF79690.1 - 7.9e-118 393.3 26.7 9e-118 393.1 18.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DNA_pol_B_palm PF14792.1 EXF79691.1 - 2e-32 111.5 0.0 4.7e-32 110.3 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EXF79691.1 - 2.3e-22 78.4 0.0 9.3e-22 76.5 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.4 EXF79691.1 - 2.7e-19 68.4 0.2 7.2e-19 67.0 0.1 1.8 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.1 EXF79691.1 - 2.5e-17 62.8 0.1 1.1e-16 60.7 0.1 2.2 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_5 PF14520.1 EXF79691.1 - 0.0017 18.4 0.3 2 8.6 0.0 3.2 3 0 0 3 3 3 2 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EXF79691.1 - 0.015 15.5 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 Nucleotidyltransferase domain HTH_3 PF01381.17 EXF79691.1 - 0.068 13.0 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix CDC45 PF02724.9 EXF79691.1 - 2.7 5.8 12.7 0.062 11.3 3.6 1.8 2 0 0 2 2 2 0 CDC45-like protein Methyltransf_31 PF13847.1 EXF79692.1 - 1.3e-10 41.0 0.0 2.2e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EXF79692.1 - 2.6e-10 39.8 0.0 4.2e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PRMT5 PF05185.11 EXF79692.1 - 1.1e-09 37.7 0.0 1.5e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_18 PF12847.2 EXF79692.1 - 9.4e-08 32.6 0.0 2.4e-07 31.3 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF79692.1 - 1.4e-07 31.5 0.0 4.3e-07 29.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF79692.1 - 2.1e-07 31.3 0.0 7.3e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 EXF79692.1 - 8.9e-06 24.6 0.1 1.2e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 EXF79692.1 - 2.9e-05 24.3 0.0 0.00011 22.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF79692.1 - 0.00014 21.5 0.0 0.00028 20.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF79692.1 - 0.001 19.4 0.0 0.0023 18.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF79692.1 - 0.0026 17.1 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EXF79692.1 - 0.004 16.2 0.0 0.0052 15.8 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.1 EXF79692.1 - 0.07 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain IPI_T4 PF11634.3 EXF79692.1 - 0.078 12.8 0.1 19 5.2 0.0 2.6 2 0 0 2 2 2 0 Nuclease inhibitor from bacteriophage T4 PMG PF05287.7 EXF79695.1 - 3.6e-06 26.9 5.4 6.3e-06 26.1 3.7 1.4 1 0 0 1 1 1 1 PMG protein Lamprin PF06403.6 EXF79695.1 - 1 9.1 10.2 1.9 8.2 7.1 1.4 1 0 0 1 1 1 0 Lamprin Pyridoxal_deC PF00282.14 EXF79696.1 - 0.00094 17.7 0.1 0.0011 17.5 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cytochrom_B562 PF07361.6 EXF79696.1 - 0.084 13.2 0.0 0.13 12.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome b562 NmrA PF05368.8 EXF79697.1 - 1.5e-13 50.5 0.0 4.6e-13 48.9 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family NAD_binding_10 PF13460.1 EXF79697.1 - 7e-09 35.9 0.1 1.7e-08 34.7 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Abhydrolase_1 PF00561.15 EXF79698.1 - 7e-22 78.1 0.0 3.8e-18 65.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EXF79698.1 - 3.3e-18 65.4 0.0 7.8e-18 64.2 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_6 PF12697.2 EXF79698.1 - 6.5e-08 32.7 0.0 3e-07 30.5 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_M3 PF01432.15 EXF79699.1 - 4.4e-121 405.1 0.0 5.7e-121 404.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 EXF79699.1 - 0.091 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Peptidase M50B-like ApoO PF09769.4 EXF79700.1 - 1.5e-47 161.2 0.3 1e-46 158.5 0.0 2.0 2 0 0 2 2 2 1 Apolipoprotein O Dus PF01207.12 EXF79701.1 - 7.8e-43 146.4 0.1 2.7e-42 144.6 0.1 1.7 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) PEP-utilizers_C PF02896.13 EXF79701.1 - 0.063 12.1 0.1 0.12 11.1 0.1 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, TIM barrel domain Pyrophosphatase PF00719.14 EXF79702.1 - 4.6e-47 159.3 0.0 1.4e-46 157.8 0.0 1.8 1 1 0 1 1 1 1 Inorganic pyrophosphatase MRP_L53 PF10780.4 EXF79703.1 - 3.3e-20 71.7 0.3 4.7e-20 71.3 0.2 1.2 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 DUF2442 PF10387.4 EXF79703.1 - 0.089 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) Sec20 PF03908.8 EXF79704.1 - 2.7e-13 49.4 3.0 3.3e-13 49.1 0.0 2.5 3 0 0 3 3 3 1 Sec20 STAT_alpha PF01017.15 EXF79704.1 - 2.9 7.5 9.7 1 9.0 0.1 2.6 2 1 0 2 2 2 0 STAT protein, all-alpha domain PEP-utilisers_N PF05524.8 EXF79704.1 - 9.9 5.9 9.3 6 6.6 0.4 3.6 4 0 0 4 4 4 0 PEP-utilising enzyme, N-terminal Aldolase_II PF00596.16 EXF79706.1 - 1.1e-37 129.4 0.0 1.3e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Calreticulin PF00262.13 EXF79707.1 - 3.7e-163 542.4 20.9 3.7e-163 542.4 14.5 1.5 2 0 0 2 2 2 1 Calreticulin family Aldedh PF00171.17 EXF79708.1 - 1.9e-131 438.6 0.3 2.3e-131 438.3 0.2 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EXF79708.1 - 0.038 12.6 0.0 0.12 11.0 0.0 1.8 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) Myb_DNA-bind_6 PF13921.1 EXF79711.1 - 5.5e-15 55.2 0.6 2.5e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EXF79711.1 - 5.5e-12 45.5 0.1 0.00012 22.0 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain TFCD_C PF12612.3 EXF79713.1 - 1.1e-24 86.9 0.0 3.9e-24 85.1 0.0 2.0 1 0 0 1 1 1 1 Tubulin folding cofactor D C terminal HEAT PF02985.17 EXF79713.1 - 0.0046 16.9 3.7 1.9 8.7 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat HET PF06985.6 EXF79714.1 - 1.4e-22 80.3 0.0 1.7e-21 76.8 0.0 2.5 3 0 0 3 3 3 1 Heterokaryon incompatibility protein (HET) Rap1-DNA-bind PF09197.5 EXF79714.1 - 0.097 13.2 0.1 0.29 11.6 0.1 1.8 2 0 0 2 2 2 0 Rap1, DNA-binding Hat1_N PF10394.4 EXF79715.1 - 3.2e-35 121.5 0.0 8.5e-35 120.1 0.0 1.7 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_7 PF13508.1 EXF79715.1 - 0.0016 18.5 0.0 0.0034 17.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EXF79715.1 - 0.0096 15.9 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EXF79715.1 - 0.085 12.9 0.0 0.28 11.3 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AAA_5 PF07728.9 EXF79716.1 - 9.3e-123 404.4 0.0 1.7e-21 76.4 0.0 9.6 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA PF00004.24 EXF79716.1 - 8.3e-29 100.4 0.0 0.0003 21.0 0.0 7.1 6 0 0 6 6 6 5 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.6 EXF79716.1 - 2.7e-27 94.9 0.0 1.4e-09 37.6 0.0 6.8 6 0 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EXF79716.1 - 8.3e-25 87.8 12.8 0.00054 19.9 0.0 9.0 7 1 0 7 7 6 5 AAA ATPase domain AAA_17 PF13207.1 EXF79716.1 - 6.1e-24 85.1 3.5 0.0038 18.0 0.0 8.1 7 0 0 7 7 6 5 AAA domain AAA_33 PF13671.1 EXF79716.1 - 9.5e-23 80.6 0.0 0.0012 18.7 0.0 8.3 7 1 0 7 7 7 4 AAA domain AAA_22 PF13401.1 EXF79716.1 - 2.8e-22 79.2 4.1 0.025 14.7 0.1 8.9 8 1 1 9 9 8 6 AAA domain AAA_14 PF13173.1 EXF79716.1 - 2.3e-19 69.5 0.0 0.00068 19.5 0.0 8.0 7 0 0 7 7 7 4 AAA domain AAA_18 PF13238.1 EXF79716.1 - 1.3e-18 67.5 1.4 0.12 12.7 0.1 7.7 6 0 0 6 6 6 4 AAA domain Sigma54_activat PF00158.21 EXF79716.1 - 2.2e-16 59.7 0.0 0.098 12.1 0.0 6.6 6 0 0 6 6 6 4 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EXF79716.1 - 1.9e-15 57.1 0.9 0.037 14.0 0.1 7.0 6 0 0 6 6 6 3 Sigma-54 interaction domain T2SE PF00437.15 EXF79716.1 - 3.2e-15 55.7 3.4 0.01 14.7 0.0 6.5 6 0 0 6 6 6 3 Type II/IV secretion system protein ABC_tran PF00005.22 EXF79716.1 - 8.6e-14 52.0 3.3 0.09 13.0 0.1 7.7 6 1 0 6 6 6 2 ABC transporter RNA_helicase PF00910.17 EXF79716.1 - 2.4e-13 50.2 0.9 0.55 10.4 0.0 6.8 6 0 0 6 6 6 3 RNA helicase AAA_19 PF13245.1 EXF79716.1 - 5.2e-13 48.5 6.9 0.043 13.5 0.0 6.6 6 0 0 6 6 6 4 Part of AAA domain NACHT PF05729.7 EXF79716.1 - 7.4e-13 48.4 5.8 0.066 12.8 0.1 6.1 5 0 0 5 5 5 4 NACHT domain UPF0079 PF02367.12 EXF79716.1 - 2.2e-12 46.6 5.4 0.034 13.7 0.0 6.1 6 0 0 6 6 6 4 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EXF79716.1 - 6.7e-12 45.6 3.8 0.26 11.2 0.0 7.9 8 0 0 8 8 7 1 AAA domain AAA_29 PF13555.1 EXF79716.1 - 7e-12 44.7 0.6 0.23 11.0 0.0 6.5 6 0 0 6 6 6 2 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EXF79716.1 - 4.2e-11 42.3 7.2 0.14 11.2 0.0 7.5 8 0 0 8 8 6 2 Zeta toxin AAA_25 PF13481.1 EXF79716.1 - 1.3e-10 40.9 1.7 0.35 10.2 0.0 6.0 6 0 0 6 6 5 2 AAA domain Mg_chelatase PF01078.16 EXF79716.1 - 1.4e-10 40.6 2.7 7.3 5.6 0.0 8.9 9 0 0 9 9 9 0 Magnesium chelatase, subunit ChlI RuvB_N PF05496.7 EXF79716.1 - 1.5e-10 40.5 2.4 0.036 13.1 0.0 5.5 5 0 0 5 5 5 3 Holliday junction DNA helicase ruvB N-terminus DUF258 PF03193.11 EXF79716.1 - 2.1e-10 40.0 1.8 0.48 9.5 0.0 6.1 6 0 0 6 6 6 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EXF79716.1 - 2.7e-10 40.3 0.2 0.11 12.2 0.0 6.7 6 0 0 6 6 6 1 Archaeal ATPase Miro PF08477.8 EXF79716.1 - 2.4e-08 34.4 3.1 6.2 7.3 0.0 6.5 6 0 0 6 6 6 0 Miro-like protein IstB_IS21 PF01695.12 EXF79716.1 - 6.2e-08 32.2 2.0 0.56 9.5 0.0 6.3 6 0 0 6 6 6 1 IstB-like ATP binding protein NTPase_1 PF03266.10 EXF79716.1 - 1e-07 31.7 5.4 1.1 8.9 0.0 6.5 6 0 0 6 6 6 2 NTPase SRP54 PF00448.17 EXF79716.1 - 1.1e-07 31.5 1.6 0.5 9.7 0.1 5.0 5 0 0 5 5 5 1 SRP54-type protein, GTPase domain MobB PF03205.9 EXF79716.1 - 1.4e-07 31.2 5.6 4.2 7.0 0.0 6.8 7 0 0 7 7 6 0 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 EXF79716.1 - 6.2e-07 28.6 2.0 0.45 9.4 0.0 5.2 5 0 0 5 5 5 1 Protein of unknown function (DUF815) cobW PF02492.14 EXF79716.1 - 7.2e-07 28.8 5.6 0.64 9.4 0.0 6.0 6 0 0 6 6 6 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EXF79716.1 - 8e-07 28.6 2.9 0.058 12.8 0.0 5.2 5 0 0 5 5 5 2 Ethanolamine utilisation - propanediol utilisation Viral_helicase1 PF01443.13 EXF79716.1 - 1.6e-05 24.5 0.3 0.59 9.6 0.0 5.4 6 0 0 6 6 5 1 Viral (Superfamily 1) RNA helicase AAA_24 PF13479.1 EXF79716.1 - 4.4e-05 23.1 2.8 11 5.5 0.0 5.9 6 0 0 6 6 6 0 AAA domain Rad17 PF03215.10 EXF79716.1 - 8.4e-05 21.4 3.5 0.43 9.1 0.0 5.0 6 0 0 6 6 6 1 Rad17 cell cycle checkpoint protein KaiC PF06745.8 EXF79716.1 - 0.0003 20.0 0.8 12 4.9 0.0 5.0 5 0 0 5 5 4 0 KaiC TIP49 PF06068.8 EXF79716.1 - 0.00037 19.3 1.6 5.3 5.6 0.0 4.8 5 0 0 5 5 5 0 TIP49 C-terminus ATP_bind_1 PF03029.12 EXF79716.1 - 0.0011 18.5 4.1 25 4.2 0.0 5.8 6 0 0 6 6 6 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.2 EXF79716.1 - 0.0012 18.0 2.1 1.3 8.0 0.0 4.6 5 0 0 5 5 5 1 P-loop containing dynein motor region D3 KTI12 PF08433.5 EXF79716.1 - 0.0021 17.3 0.0 0.32 10.1 0.0 4.0 3 0 0 3 3 3 1 Chromatin associated protein KTI12 MMR_HSR1 PF01926.18 EXF79716.1 - 0.0036 17.2 3.8 56 3.7 0.0 6.3 7 0 0 7 7 6 0 50S ribosome-binding GTPase DEAD PF00270.24 EXF79716.1 - 0.005 16.3 0.9 2.2 7.7 0.0 4.0 4 0 0 4 4 3 1 DEAD/DEAH box helicase CbiA PF01656.18 EXF79716.1 - 0.015 14.7 0.8 9.5 5.5 0.0 4.0 4 0 0 4 4 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_6 PF12774.2 EXF79716.1 - 0.62 9.5 0.1 18 4.7 0.0 3.4 4 0 0 4 4 3 0 Hydrolytic ATP binding site of dynein motor region D1 Hpr_kinase_C PF07475.7 EXF79716.1 - 0.96 8.7 3.2 1.4 8.2 0.1 2.8 4 0 0 4 4 3 0 HPr Serine kinase C-terminal domain Ribosomal_L12 PF00542.14 EXF79717.1 - 4e-18 65.1 4.9 4e-18 65.1 3.4 2.5 3 0 0 3 3 3 1 Ribosomal protein L7/L12 C-terminal domain PP2C_C PF07830.8 EXF79717.1 - 0.43 10.7 2.7 3.8 7.6 0.1 2.7 2 1 1 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain Ribosomal_60s PF00428.14 EXF79717.1 - 2.1 8.7 16.1 0.64 10.4 7.6 2.4 2 1 0 2 2 2 0 60s Acidic ribosomal protein CTK3 PF12243.3 EXF79718.1 - 1.9e-59 199.2 1.2 2.5e-59 198.8 0.9 1.1 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTK3_C PF12350.3 EXF79718.1 - 4.4e-21 74.6 4.3 1.4e-20 73.0 3.0 1.9 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 C-terminus MAM33 PF02330.11 EXF79718.1 - 0.017 14.8 0.4 0.028 14.2 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial glycoprotein P5CR_dimer PF14748.1 EXF79719.1 - 3.7e-34 116.9 1.8 6.2e-34 116.2 0.9 1.7 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EXF79719.1 - 4.3e-12 46.2 0.9 1.7e-10 41.1 0.0 2.6 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EXF79719.1 - 0.12 11.7 0.8 0.23 10.9 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EXF79719.1 - 0.27 10.9 1.5 0.8 9.4 0.0 2.1 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox_2 PF07992.9 EXF79720.1 - 1.1e-34 120.0 0.0 1.8e-34 119.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF79720.1 - 4.6e-14 52.5 0.0 2.1e-11 44.0 0.0 3.4 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF79720.1 - 1.9e-09 37.9 0.0 0.0068 16.4 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF79720.1 - 7e-06 25.1 0.3 0.36 9.6 0.1 3.4 3 1 1 4 4 4 3 FAD binding domain K_oxygenase PF13434.1 EXF79720.1 - 0.0022 16.9 0.0 11 4.8 0.0 3.8 3 1 1 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EXF79720.1 - 0.024 14.6 0.0 6.2 6.9 0.0 2.6 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain BP28CT PF08146.7 EXF79721.1 - 1.8e-39 134.8 0.4 1.8e-39 134.8 0.3 3.4 3 0 0 3 3 3 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.3 EXF79721.1 - 1.5e-24 86.3 8.9 4.2e-24 84.8 0.1 5.7 6 0 0 6 6 6 1 U3 small nucleolar RNA-associated protein 10 HEAT PF02985.17 EXF79721.1 - 2.6e-06 27.0 15.4 0.012 15.5 0.0 8.0 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.1 EXF79721.1 - 3.1e-05 24.1 18.9 0.15 12.4 0.0 7.2 6 1 2 8 8 8 4 HEAT repeats HEAT_EZ PF13513.1 EXF79721.1 - 3.4 8.2 25.0 0.12 12.9 0.8 7.5 6 3 2 8 8 8 0 HEAT-like repeat Lipase_GDSL_2 PF13472.1 EXF79722.1 - 7.8e-21 75.0 0.0 9.4e-21 74.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EXF79722.1 - 5.1e-15 55.9 0.0 6.4e-15 55.6 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Isochorismatase PF00857.15 EXF79724.1 - 6.5e-31 107.5 0.1 8e-31 107.2 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family HK PF02110.10 EXF79725.1 - 5e-75 251.8 0.7 8.6e-75 251.0 0.5 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family TMP-TENI PF02581.12 EXF79725.1 - 1e-57 194.1 1.0 1.6e-57 193.5 0.7 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase/TENI TPP_enzyme_N PF02776.13 EXF79725.1 - 0.02 14.3 0.5 0.095 12.1 0.4 2.1 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Fungal_trans PF04082.13 EXF79726.1 - 0.00011 21.1 0.0 0.00022 20.1 0.0 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain DENN PF02141.16 EXF79726.1 - 0.046 13.4 0.3 0.088 12.5 0.2 1.4 1 0 0 1 1 1 0 DENN (AEX-3) domain Zn_clus PF00172.13 EXF79726.1 - 0.063 13.2 11.0 0.12 12.3 7.6 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Aminotran_1_2 PF00155.16 EXF79727.1 - 2.8e-81 273.2 0.0 3.7e-81 272.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EXF79727.1 - 2.5e-05 22.7 0.0 3.9e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EXF79727.1 - 5e-05 22.2 0.0 0.0001 21.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V PTS_EIIA_2 PF00359.17 EXF79727.1 - 0.035 13.8 0.0 0.074 12.7 0.0 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 DUF3405 PF11885.3 EXF79727.1 - 0.12 10.6 0.0 0.17 10.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) SNF2_N PF00176.18 EXF79728.1 - 7.1e-44 149.7 0.0 1.3e-43 148.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EXF79728.1 - 2.5e-14 52.9 0.4 9.2e-14 51.0 0.3 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HPS3_C PF14763.1 EXF79728.1 - 0.062 12.2 0.5 1.4 7.8 0.0 2.8 3 0 0 3 3 3 0 Hermansky-Pudlak syndrome 3, C-terminal GSH_synth_ATP PF03917.12 EXF79729.1 - 5.1e-110 367.5 0.0 6.4e-110 367.2 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EXF79729.1 - 1.9e-31 108.2 0.0 3.3e-31 107.4 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic glutathione synthase SSB PF00436.20 EXF79730.1 - 7.3e-19 67.5 0.0 9.1e-19 67.2 0.0 1.1 1 0 0 1 1 1 1 Single-strand binding protein family F1F0-ATPsyn_F PF10791.4 EXF79730.1 - 0.15 12.3 0.3 0.84 9.9 0.0 2.0 2 1 0 2 2 2 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi Erf4 PF10256.4 EXF79731.1 - 2.7e-29 101.4 0.0 5.1e-29 100.5 0.0 1.5 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family HsbA PF12296.3 EXF79732.1 - 0.021 14.6 0.3 0.04 13.7 0.2 1.4 1 0 0 1 1 1 0 Hydrophobic surface binding protein A DUF1604 PF07713.8 EXF79733.1 - 5.6e-39 131.8 0.8 1.8e-38 130.1 0.6 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) G-patch PF01585.18 EXF79733.1 - 1.9e-06 27.5 1.8 1.8e-05 24.4 1.0 2.5 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.2 EXF79733.1 - 0.00053 19.7 0.2 0.00053 19.7 0.2 2.2 2 0 0 2 2 2 1 DExH-box splicing factor binding site Pkinase PF00069.20 EXF79734.1 - 1.1e-77 260.7 0.0 1.8e-77 260.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF79734.1 - 7.5e-40 136.6 0.1 2.3e-39 135.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EXF79734.1 - 3.3e-18 64.8 0.2 5.5e-18 64.1 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kdo PF06293.9 EXF79734.1 - 5.8e-06 25.5 0.1 1.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EXF79734.1 - 7.4e-05 21.8 0.0 0.00016 20.7 0.0 1.5 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EXF79734.1 - 0.0062 16.3 0.0 0.02 14.6 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EXF79734.1 - 0.0064 15.8 0.0 0.018 14.4 0.0 1.7 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.4 EXF79734.1 - 0.0092 15.3 0.0 0.021 14.1 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL WaaY PF06176.6 EXF79734.1 - 0.14 11.3 0.1 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) Rcd1 PF04078.8 EXF79735.1 - 7.6e-131 434.7 4.1 7.6e-131 434.7 2.8 1.4 2 0 0 2 2 1 1 Cell differentiation family, Rcd1-like Pex14_N PF04695.8 EXF79735.1 - 0.0077 16.2 10.0 0.012 15.6 6.9 1.4 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Ycf1 PF05758.7 EXF79735.1 - 0.014 13.1 0.5 0.017 12.8 0.3 1.1 1 0 0 1 1 1 0 Ycf1 Herpes_UL4 PF03277.8 EXF79735.1 - 0.035 13.3 4.7 0.13 11.4 3.3 1.9 2 0 0 2 2 2 0 Herpesvirus UL4 family Spore_coat_CotO PF14153.1 EXF79735.1 - 0.043 13.2 12.8 0.058 12.8 8.9 1.2 1 0 0 1 1 1 0 Spore coat protein CotO FCP1_C PF09309.5 EXF79735.1 - 0.069 12.4 6.4 0.1 11.8 4.5 1.2 1 0 0 1 1 1 0 FCP1, C-terminal DUF1800 PF08811.6 EXF79735.1 - 0.08 11.8 12.9 0.14 11.0 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1800) Band_3_cyto PF07565.8 EXF79735.1 - 0.18 11.3 9.8 0.069 12.6 4.8 1.8 2 0 0 2 2 2 0 Band 3 cytoplasmic domain TFIIA PF03153.8 EXF79735.1 - 0.36 10.6 27.0 0.49 10.2 18.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EXF79735.1 - 0.46 8.6 34.8 0.57 8.3 24.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.1 EXF79735.1 - 0.6 7.7 30.8 0.79 7.3 21.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Kei1 PF08552.6 EXF79735.1 - 0.75 9.4 6.7 1.4 8.5 4.6 1.5 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Suf PF05843.9 EXF79735.1 - 1.7 8.3 16.8 2.5 7.7 11.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ThylakoidFormat PF11264.3 EXF79735.1 - 2.3 7.7 14.6 13 5.2 9.1 2.4 3 0 0 3 3 2 0 Thylakoid formation protein Ctr PF04145.10 EXF79735.1 - 2.5 8.1 4.5 1.4 8.9 1.5 1.8 2 0 0 2 2 1 0 Ctr copper transporter family FAM60A PF15396.1 EXF79735.1 - 3 7.5 8.7 4.7 6.8 6.0 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Miff PF05644.6 EXF79735.1 - 3 7.3 11.4 4.7 6.7 7.9 1.2 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff UPF0560 PF10577.4 EXF79735.1 - 3.9 5.5 22.0 5.1 5.2 15.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DnaJ-X PF14308.1 EXF79735.1 - 4.3 6.5 12.6 8.3 5.6 8.7 1.4 1 0 0 1 1 1 0 X-domain of DnaJ-containing Spt20 PF12090.3 EXF79735.1 - 5.9 6.1 13.6 15 4.8 9.4 1.7 1 0 0 1 1 1 0 Spt20 family DUF3499 PF12005.3 EXF79735.1 - 5.9 7.0 9.8 12 6.0 6.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3499) DUF4407 PF14362.1 EXF79735.1 - 7.7 5.3 14.1 12 4.7 9.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Neur_chan_memb PF02932.11 EXF79735.1 - 8.5 6.1 8.8 13 5.5 6.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region bZIP_1 PF00170.16 EXF79736.1 - 0.0003 20.6 8.4 0.00053 19.9 5.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EXF79736.1 - 0.003 17.3 7.8 0.0049 16.6 5.4 1.2 1 0 0 1 1 1 1 Basic region leucine zipper SRP-alpha_N PF04086.8 EXF79736.1 - 0.14 11.5 2.5 0.18 11.1 1.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CIA30 PF08547.7 EXF79737.1 - 8.1e-36 123.2 0.0 1.1e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.8 EXF79737.1 - 0.017 14.8 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) Homoserine_dh PF00742.14 EXF79738.1 - 2.4e-52 177.1 0.0 3.1e-52 176.8 0.0 1.1 1 0 0 1 1 1 1 Homoserine dehydrogenase NAD_binding_3 PF03447.11 EXF79738.1 - 9.3e-17 61.4 0.0 1.6e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain DUF1295 PF06966.7 EXF79739.1 - 2.7e-40 138.1 1.0 1.4e-38 132.5 0.7 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 EXF79739.1 - 0.0031 17.2 0.0 0.0078 15.9 0.0 1.7 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 EXF79739.1 - 0.039 14.0 0.0 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 Phospholipid methyltransferase FBPase PF00316.15 EXF79740.1 - 1.9e-123 411.4 0.0 2.1e-123 411.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase PEX11 PF05648.9 EXF79741.1 - 2.8e-74 249.1 0.3 3.1e-74 249.0 0.2 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) RRM_1 PF00076.17 EXF79742.1 - 4.2e-24 83.9 0.0 3.4e-11 42.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF79742.1 - 7.7e-18 64.2 0.0 6e-08 32.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF79742.1 - 4.5e-14 52.0 0.0 3.7e-06 26.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PXA PF02194.10 EXF79743.1 - 9.2e-55 185.0 0.3 9.2e-55 185.0 0.2 2.3 2 0 0 2 2 2 1 PXA domain Methyltransf_4 PF02390.12 EXF79743.1 - 1.4e-51 174.3 0.0 2.9e-51 173.3 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Nexin_C PF08628.7 EXF79743.1 - 2.9e-32 111.1 0.1 1.1e-31 109.2 0.1 2.1 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 EXF79743.1 - 3.1e-21 75.2 0.5 9.7e-21 73.6 0.4 2.0 1 0 0 1 1 1 1 PX domain RGS PF00615.14 EXF79743.1 - 5.8e-12 45.7 0.0 2.3e-11 43.8 0.0 2.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain Methyltransf_18 PF12847.2 EXF79743.1 - 0.0018 18.8 0.0 0.0053 17.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EXF79743.1 - 0.0029 17.2 0.0 0.007 16.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FmrO PF07091.6 EXF79743.1 - 0.0091 15.0 0.0 0.033 13.1 0.0 1.9 2 0 0 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) Methyltransf_31 PF13847.1 EXF79743.1 - 0.012 15.1 0.0 0.034 13.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EXF79743.1 - 0.028 13.8 0.0 0.1 11.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_12 PF08242.7 EXF79743.1 - 0.034 14.6 0.0 0.11 13.0 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EXF79743.1 - 0.043 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EXF79743.1 - 0.048 13.6 0.0 0.14 12.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EXF79743.1 - 0.077 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 EXF79743.1 - 0.11 13.0 0.0 0.33 11.4 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Cytochrom_B558a PF05038.8 EXF79744.1 - 0.019 14.5 0.1 0.022 14.4 0.1 1.1 1 0 0 1 1 1 0 Cytochrome Cytochrome b558 alpha-subunit Mito_fiss_reg PF05308.6 EXF79744.1 - 0.084 12.2 2.2 0.1 11.9 1.5 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Adeno_E3_14_5 PF04834.7 EXF79744.1 - 0.18 12.2 1.7 0.27 11.6 1.1 1.3 1 1 0 1 1 1 0 Early E3 14.5 kDa protein DUF4078 PF13300.1 EXF79745.1 - 4.1e-29 100.5 17.7 4.1e-29 100.5 12.3 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4078) Cwf_Cwc_15 PF04889.7 EXF79745.1 - 0.72 9.5 36.5 0.1 12.3 10.1 2.1 1 1 1 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Mitofilin PF09731.4 EXF79746.1 - 0.075 11.6 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Glyco_hydro_43 PF04616.9 EXF79747.1 - 9.9e-63 211.8 0.0 1.6e-62 211.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Peptidase_M14 PF00246.19 EXF79748.1 - 4.6e-20 72.3 0.0 7.7e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF2817 PF10994.3 EXF79748.1 - 0.012 14.7 0.0 0.02 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) CorA PF01544.13 EXF79749.1 - 0.0016 17.5 0.2 0.0036 16.3 0.1 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein IFT57 PF10498.4 EXF79749.1 - 0.0048 15.6 1.5 0.013 14.2 1.1 1.7 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Peptidase_M35 PF02102.10 EXF79751.1 - 3e-57 193.9 16.4 3.5e-57 193.6 11.4 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EXF79751.1 - 5.4e-14 52.9 0.7 1.5e-13 51.4 0.1 1.9 1 1 1 2 2 2 1 Lysine-specific metallo-endopeptidase DUF1120 PF06551.7 EXF79751.1 - 0.0042 17.3 7.0 0.13 12.5 2.4 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1120) Asn_synthase PF00733.16 EXF79753.1 - 9.2e-54 182.6 0.0 1.7e-53 181.7 0.0 1.4 2 0 0 2 2 2 1 Asparagine synthase GATase_7 PF13537.1 EXF79753.1 - 2.2e-36 124.3 0.0 4.8e-36 123.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EXF79753.1 - 7e-33 113.4 0.0 4e-32 110.9 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EXF79753.1 - 1.4e-06 27.7 0.0 3.1e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 EXF79753.1 - 0.086 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 NAD synthase GATase_2 PF00310.16 EXF79753.1 - 0.089 11.4 0.0 2.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Glutamine amidotransferases class-II PS_Dcarbxylase PF02666.10 EXF79754.1 - 7.1e-49 165.8 0.0 1e-48 165.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase RnfC_N PF13375.1 EXF79754.1 - 0.089 12.5 0.1 7.5 6.3 0.0 2.4 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain Cytochrom_B561 PF03188.11 EXF79755.1 - 0.091 12.5 8.6 0.2 11.4 6.0 1.6 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 DUF4079 PF13301.1 EXF79755.1 - 2.2 8.2 14.2 2.4 8.1 2.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4079) MFS_2 PF13347.1 EXF79756.1 - 2e-09 36.3 7.4 2e-09 36.3 5.1 2.8 2 1 0 3 3 3 1 MFS/sugar transport protein RasGAP PF00616.14 EXF79756.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase Na_H_Exchanger PF00999.16 EXF79757.1 - 1.2e-68 231.4 39.6 1.4e-68 231.1 27.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family EVC2_like PF12297.3 EXF79757.1 - 4 5.9 7.3 0.5 8.9 0.6 2.4 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein Myb_DNA-bind_6 PF13921.1 EXF79758.1 - 9.3e-15 54.4 0.5 3.9e-14 52.5 0.4 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EXF79758.1 - 0.0052 16.7 0.1 0.013 15.4 0.1 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Herpes_UL87 PF03043.9 EXF79758.1 - 0.011 14.1 0.1 0.011 14.1 0.0 3.6 2 1 1 3 3 3 0 Herpesvirus UL87 family MAPEG PF01124.13 EXF79759.1 - 5.8e-14 51.8 1.4 6.9e-14 51.5 1.0 1.1 1 0 0 1 1 1 1 MAPEG family Polysacc_lyase PF14099.1 EXF79761.1 - 0.00035 20.2 7.8 0.00052 19.7 5.4 1.3 1 0 0 1 1 1 1 Polysaccharide lyase PAT1 PF09770.4 EXF79762.1 - 5 5.2 22.6 6.2 4.9 15.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SNF5 PF04855.7 EXF79763.1 - 1.4e-73 247.3 0.0 2.4e-73 246.6 0.0 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 Peptidase_M24 PF00557.19 EXF79764.1 - 1.3e-12 47.7 0.0 1.8e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 PHD PF00628.24 EXF79765.1 - 2.3e-12 46.3 19.0 9.3e-08 31.6 6.1 2.5 2 0 0 2 2 2 2 PHD-finger Prok-RING_1 PF14446.1 EXF79765.1 - 0.0063 16.2 14.1 0.021 14.5 1.6 2.4 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.1 EXF79765.1 - 0.019 15.0 5.5 0.058 13.5 1.0 2.4 2 0 0 2 2 2 0 PHD-like zinc-binding domain zf-PHD-like PF15446.1 EXF79765.1 - 6.2 6.0 10.3 11 5.2 2.6 2.4 2 0 0 2 2 2 0 PHD/FYVE-zinc-finger like domain PUF PF00806.14 EXF79766.1 - 8.7e-26 87.9 0.0 0.00022 20.5 0.0 5.5 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat RRM_1 PF00076.17 EXF79766.1 - 1.9e-12 46.6 0.0 4.6e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF79766.1 - 3.8e-06 26.7 0.0 9.7e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF79766.1 - 6e-06 26.0 0.0 1.3e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_2 PF07724.9 EXF79767.1 - 8.5e-48 162.4 0.0 4.5e-46 156.8 0.0 3.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.24 EXF79767.1 - 6.2e-28 97.6 0.0 8.4e-15 55.1 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EXF79767.1 - 1.5e-23 82.4 2.3 4e-23 81.1 0.3 2.8 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EXF79767.1 - 1.5e-16 60.4 0.0 1.8e-10 40.7 0.0 3.2 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EXF79767.1 - 4.9e-16 59.2 17.4 3.6e-07 30.3 0.0 6.6 3 2 2 5 5 4 2 AAA ATPase domain AAA_22 PF13401.1 EXF79767.1 - 1.6e-13 50.9 0.3 4.8e-05 23.5 0.0 4.3 2 2 1 3 3 3 2 AAA domain Sigma54_activat PF00158.21 EXF79767.1 - 1.1e-09 37.9 0.0 1.4e-06 27.9 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain Clp_N PF02861.15 EXF79767.1 - 9.7e-09 35.0 2.2 4.9e-05 23.1 0.1 3.9 3 0 0 3 3 3 1 Clp amino terminal domain AAA_17 PF13207.1 EXF79767.1 - 8.1e-08 33.1 8.2 0.0059 17.4 0.9 4.3 3 2 0 3 3 2 2 AAA domain AAA_19 PF13245.1 EXF79767.1 - 1.4e-07 31.1 0.0 0.021 14.5 0.0 3.4 3 1 0 3 3 2 2 Part of AAA domain IstB_IS21 PF01695.12 EXF79767.1 - 4.9e-07 29.3 0.0 0.021 14.2 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 EXF79767.1 - 3.3e-06 26.4 0.0 0.067 12.3 0.1 3.7 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EXF79767.1 - 1.4e-05 25.0 0.0 0.24 11.3 0.0 3.4 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EXF79767.1 - 1.6e-05 24.7 12.9 0.0078 15.9 0.2 5.7 4 2 1 5 5 4 1 Archaeal ATPase AAA_3 PF07726.6 EXF79767.1 - 1.6e-05 24.5 0.1 0.6 9.7 0.0 4.3 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EXF79767.1 - 2e-05 24.5 0.2 0.19 11.6 0.0 3.5 3 1 0 3 3 3 2 AAA domain MobB PF03205.9 EXF79767.1 - 2.2e-05 24.1 0.0 0.32 10.6 0.0 2.9 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EXF79767.1 - 2.4e-05 24.4 0.0 0.31 11.2 0.0 2.9 3 0 0 3 3 2 2 RNA helicase AAA_18 PF13238.1 EXF79767.1 - 2.6e-05 24.5 10.8 0.013 15.8 0.0 4.6 5 1 0 5 5 3 2 AAA domain T2SE PF00437.15 EXF79767.1 - 3.3e-05 22.9 0.0 0.0041 16.0 0.0 2.7 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.1 EXF79767.1 - 0.00012 21.5 0.3 0.9 8.8 0.0 3.8 3 1 0 4 4 4 2 AAA domain Zeta_toxin PF06414.7 EXF79767.1 - 0.00014 20.9 0.1 0.017 14.2 0.0 2.9 3 0 0 3 3 2 1 Zeta toxin ABC_tran PF00005.22 EXF79767.1 - 0.0004 20.6 0.1 0.53 10.5 0.0 3.2 3 0 0 3 3 2 1 ABC transporter ResIII PF04851.10 EXF79767.1 - 0.00044 20.1 2.2 0.083 12.7 0.0 4.0 3 1 2 5 5 4 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 EXF79767.1 - 0.00059 19.4 0.6 1.9 7.9 0.1 3.6 3 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 EXF79767.1 - 0.00071 18.7 0.0 0.36 10.0 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EXF79767.1 - 0.00087 18.7 0.0 1 8.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain NACHT PF05729.7 EXF79767.1 - 0.001 18.7 0.0 0.18 11.4 0.0 3.1 2 0 0 2 2 2 1 NACHT domain KTI12 PF08433.5 EXF79767.1 - 0.0011 18.1 0.4 4.9 6.2 0.0 3.8 3 0 0 3 3 3 0 Chromatin associated protein KTI12 AAA_10 PF12846.2 EXF79767.1 - 0.0016 17.9 6.3 0.13 11.6 0.0 4.7 4 2 0 5 5 5 1 AAA-like domain NTPase_1 PF03266.10 EXF79767.1 - 0.0017 18.1 0.1 0.22 11.2 0.0 3.5 4 0 0 4 4 3 1 NTPase Torsin PF06309.6 EXF79767.1 - 0.002 18.0 0.0 0.011 15.6 0.0 2.1 2 0 0 2 2 2 1 Torsin SRP54 PF00448.17 EXF79767.1 - 0.013 14.9 0.0 4 6.8 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.1 EXF79767.1 - 0.016 15.5 8.7 1.8 8.8 0.1 4.0 3 1 0 3 3 3 0 AAA domain UPF0079 PF02367.12 EXF79767.1 - 0.019 14.5 0.0 8 6.1 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_21 PF13304.1 EXF79767.1 - 0.021 14.7 0.0 2.4 8.0 0.0 2.9 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.12 EXF79767.1 - 0.043 13.3 0.0 7.4 6.0 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 EXF79767.1 - 0.073 12.5 0.0 6.1 6.3 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EXF79767.1 - 0.097 12.6 0.1 2.6 8.0 0.0 3.3 3 1 0 3 3 2 0 50S ribosome-binding GTPase V_ATPase_I PF01496.14 EXF79767.1 - 0.45 8.3 2.0 0.78 7.5 1.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mhr1 PF12829.2 EXF79768.1 - 2.1e-29 101.2 0.1 3.5e-29 100.4 0.1 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination Sulfotransfer_3 PF13469.1 EXF79769.1 - 0.0076 17.2 0.1 0.017 16.0 0.1 1.6 1 1 0 1 1 1 1 Sulfotransferase family GPI-anchored PF10342.4 EXF79770.1 - 7.2e-22 77.6 3.1 7.2e-22 77.6 2.1 2.8 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4448 PF14610.1 EXF79770.1 - 0.00071 19.1 0.2 0.0011 18.5 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) ABM PF03992.11 EXF79771.1 - 0.00017 21.5 0.0 0.046 13.7 0.0 2.5 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase DUF3764 PF12594.3 EXF79771.1 - 0.00078 19.1 0.0 0.0014 18.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3764) DUF1330 PF07045.6 EXF79771.1 - 0.034 14.0 0.1 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1330) KH_1 PF00013.24 EXF79772.1 - 1e-39 133.9 5.9 1.3e-16 59.9 0.6 3.3 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EXF79772.1 - 4.9e-31 105.8 12.7 2.6e-11 42.9 2.8 3.4 3 0 0 3 3 3 3 KH domain KH_2 PF07650.12 EXF79772.1 - 1.5e-12 46.8 4.3 0.0066 15.9 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EXF79772.1 - 2e-05 24.1 1.0 0.61 9.7 0.0 3.3 3 0 0 3 3 3 2 KH domain KH_5 PF13184.1 EXF79772.1 - 0.0077 16.0 6.6 0.78 9.5 0.1 3.2 3 0 0 3 3 3 2 NusA-like KH domain CENP-K PF11802.3 EXF79773.1 - 5.5e-12 45.4 3.1 5.9e-05 22.4 0.0 2.4 2 1 0 2 2 2 2 Centromere-associated protein K DUF4439 PF14530.1 EXF79773.1 - 0.019 15.4 3.0 5.1 7.5 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4439) PSII_Pbs27 PF13326.1 EXF79773.1 - 0.043 13.8 1.1 0.75 9.7 0.0 2.8 3 0 0 3 3 3 0 Photosystem II Pbs27 DUF342 PF03961.8 EXF79773.1 - 0.19 10.0 5.5 2 6.7 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF342) IncA PF04156.9 EXF79773.1 - 1.9 8.0 20.6 1.6 8.2 0.5 2.8 3 0 0 3 3 3 0 IncA protein Atg14 PF10186.4 EXF79773.1 - 3.3 6.5 10.1 1.5 7.6 0.0 2.3 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Phos_pyr_kin PF08543.7 EXF79774.1 - 1e-11 44.5 0.0 2.1e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EXF79774.1 - 1.3e-08 34.3 1.3 2e-07 30.4 0.2 2.6 2 1 0 2 2 2 1 pfkB family carbohydrate kinase PCNA_N PF00705.13 EXF79775.1 - 1.5e-52 176.4 5.0 2e-52 176.0 2.4 1.8 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EXF79775.1 - 9.5e-51 171.0 0.0 1.5e-50 170.3 0.0 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.8 EXF79775.1 - 3.6e-10 39.3 0.0 4.4e-10 39.1 0.0 1.1 1 0 0 1 1 1 1 Rad9 Rad1 PF02144.11 EXF79775.1 - 1.1e-06 27.6 0.3 3.9e-05 22.5 0.2 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Hus1 PF04005.7 EXF79775.1 - 0.0011 18.0 0.1 0.011 14.7 0.0 2.1 2 1 0 2 2 2 1 Hus1-like protein DNA_pol3_beta_3 PF02768.10 EXF79775.1 - 0.067 12.7 0.1 0.36 10.3 0.0 2.2 2 2 1 3 3 3 0 DNA polymerase III beta subunit, C-terminal domain Vezatin PF12632.2 EXF79776.1 - 5.5e-53 179.6 0.0 8.8e-53 178.9 0.0 1.3 1 0 0 1 1 1 1 Mysoin-binding motif of peroxisomes DUF4231 PF14015.1 EXF79776.1 - 0.00051 19.9 1.4 0.01 15.7 0.8 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4231) Wzy_C PF04932.10 EXF79776.1 - 0.072 12.8 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 O-Antigen ligase Rab5ip PF07019.7 EXF79777.1 - 1.6e-22 79.4 6.7 2e-22 79.1 4.6 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF3611 PF12263.3 EXF79777.1 - 0.34 10.2 3.3 0.51 9.7 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3611) GTP_EFTU PF00009.22 EXF79778.1 - 4.5e-10 39.2 0.0 2e-09 37.1 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EXF79778.1 - 0.057 12.9 1.2 0.13 11.7 0.9 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SNARE PF05739.14 EXF79779.1 - 0.0017 18.0 0.8 0.0017 18.0 0.5 2.7 2 1 0 2 2 2 1 SNARE domain OB_NTP_bind PF07717.11 EXF79781.1 - 5.1e-16 58.5 0.0 1.1e-15 57.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EXF79781.1 - 1.4e-14 53.9 0.0 4.1e-14 52.4 0.0 1.9 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EXF79781.1 - 9.6e-14 51.0 0.2 7.3e-13 48.1 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 EXF79781.1 - 9.7e-08 31.6 0.0 6.2e-07 29.0 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase T2SE PF00437.15 EXF79781.1 - 0.00049 19.0 0.0 0.00098 18.1 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 EXF79781.1 - 0.0017 17.8 0.0 0.0039 16.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EXF79781.1 - 0.0038 17.3 0.0 0.011 15.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EXF79781.1 - 0.014 15.3 0.3 0.15 12.0 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.22 EXF79781.1 - 0.021 15.1 0.0 0.083 13.1 0.0 2.0 1 0 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.13 EXF79781.1 - 0.061 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Patatin PF01734.17 EXF79782.1 - 5.1e-28 98.3 0.0 1e-27 97.4 0.0 1.5 1 0 0 1 1 1 1 Patatin-like phospholipase TPR_12 PF13424.1 EXF79782.1 - 3.1e-19 68.6 5.4 9.2e-09 35.1 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat NB-ARC PF00931.17 EXF79782.1 - 3.6e-13 49.0 0.0 7.8e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.1 EXF79782.1 - 3.4e-09 36.3 18.5 0.00071 19.4 0.3 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat Complex1_LYR PF05347.10 EXF79782.1 - 5.4e-08 32.5 0.6 2.5e-07 30.3 0.0 2.5 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EXF79782.1 - 2.3e-06 27.7 0.3 2.3e-05 24.5 0.0 2.7 2 0 0 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EXF79782.1 - 0.00077 19.9 0.0 0.0047 17.3 0.0 2.4 1 0 0 1 1 1 1 Complex1_LYR-like PPR PF01535.15 EXF79782.1 - 0.0041 16.9 0.1 11 6.2 0.0 4.0 3 0 0 3 3 3 1 PPR repeat TPR_4 PF07721.9 EXF79782.1 - 0.0073 16.6 14.9 15 6.3 0.1 6.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Ubiq-assoc PF09145.5 EXF79782.1 - 0.012 15.4 0.1 0.043 13.6 0.1 2.0 1 0 0 1 1 1 0 Ubiquitin-associated TPR_14 PF13428.1 EXF79782.1 - 0.036 14.6 11.2 9.3 7.1 0.1 6.1 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EXF79782.1 - 0.046 13.6 7.1 3.7 7.7 0.0 5.0 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EXF79782.1 - 0.059 13.1 9.5 5.5 7.0 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat Pyr_redox_3 PF13738.1 EXF79783.1 - 1.2e-18 67.9 0.0 2.1e-18 67.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF79783.1 - 3e-07 30.3 0.0 7.5e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EXF79783.1 - 7.5e-05 21.7 0.0 0.039 12.8 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EXF79783.1 - 0.0012 17.0 0.3 0.021 13.0 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 EXF79783.1 - 0.0015 18.2 0.0 0.035 13.8 0.0 2.8 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EXF79783.1 - 0.0022 17.8 0.0 0.23 11.3 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GPI-anchored PF10342.4 EXF79786.1 - 1.1e-18 67.4 5.9 1.1e-18 67.4 4.1 3.0 2 1 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Hex_IIIa PF02455.11 EXF79786.1 - 0.91 8.1 6.1 1.2 7.7 4.3 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Macoilin PF09726.4 EXF79786.1 - 7.3 4.7 18.7 7.8 4.6 13.0 1.1 1 0 0 1 1 1 0 Transmembrane protein SpoIIE PF07228.7 EXF79787.1 - 9.1e-10 38.5 0.4 3.8e-09 36.5 0.3 2.0 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.1 EXF79787.1 - 1.7e-08 34.1 0.2 3.3e-08 33.1 0.2 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.16 EXF79787.1 - 1.2e-07 31.4 1.2 0.011 15.1 0.0 2.9 3 0 0 3 3 3 2 Protein phosphatase 2C Fer2_3 PF13085.1 EXF79788.1 - 1.6e-32 111.5 0.0 2.6e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EXF79788.1 - 3.2e-09 36.9 6.4 3.2e-09 36.9 4.4 2.1 3 0 0 3 3 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EXF79788.1 - 3.2e-09 36.6 4.4 3.2e-09 36.6 3.0 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_18 PF13746.1 EXF79788.1 - 7.1e-06 26.3 5.9 2.7e-05 24.4 1.0 2.6 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_10 PF13237.1 EXF79788.1 - 7e-05 22.5 4.2 7e-05 22.5 2.9 2.2 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EXF79788.1 - 7e-05 23.0 4.1 0.043 14.0 0.4 3.1 3 0 0 3 3 3 2 4Fe-4S dicluster domain Fer2 PF00111.22 EXF79788.1 - 0.00075 19.1 2.0 0.002 17.8 0.2 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.2 EXF79788.1 - 0.0014 19.0 4.2 0.0014 19.0 2.9 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain DNA_pol3_tau_4 PF12168.3 EXF79788.1 - 0.14 12.5 1.9 0.87 10.0 0.2 2.4 2 0 0 2 2 2 0 DNA polymerase III subunits tau domain IV DnaB-binding Fer4_2 PF12797.2 EXF79788.1 - 1.8 8.6 16.7 1.9 8.5 3.1 3.3 3 0 0 3 3 3 0 4Fe-4S binding domain Fer4_15 PF13459.1 EXF79788.1 - 3.8 8.1 6.9 1.2 9.8 0.1 2.7 3 0 0 3 3 2 0 4Fe-4S single cluster domain FAD_binding_2 PF00890.19 EXF79789.1 - 1e-123 413.3 4.7 1.3e-123 412.9 3.3 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EXF79789.1 - 1.2e-45 154.5 0.1 1.8e-45 153.9 0.1 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EXF79789.1 - 4.8e-07 29.8 0.1 0.0027 17.5 0.1 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF79789.1 - 1.2e-05 24.5 0.1 0.0089 15.1 0.0 2.5 3 0 0 3 3 3 2 Thi4 family GIDA PF01134.17 EXF79789.1 - 4.9e-05 22.3 1.4 0.016 14.0 1.5 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.19 EXF79789.1 - 0.00039 19.4 0.1 0.0046 15.9 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EXF79789.1 - 0.0032 16.5 0.7 0.0088 15.1 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EXF79789.1 - 0.12 10.7 1.4 0.28 9.6 0.4 2.0 2 0 0 2 2 2 0 HI0933-like protein AIRC PF00731.15 EXF79791.1 - 8.7e-61 203.6 1.5 1.9e-60 202.4 0.7 1.8 2 0 0 2 2 2 1 AIR carboxylase ATP-grasp PF02222.17 EXF79791.1 - 5.9e-51 172.2 0.0 1.2e-50 171.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EXF79791.1 - 8.5e-12 45.1 0.1 1.8e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EXF79791.1 - 3.7e-07 29.7 0.0 8.7e-07 28.5 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus XdhC_C PF13478.1 EXF79791.1 - 0.00014 22.1 0.3 0.28 11.4 0.0 2.7 3 0 0 3 3 3 2 XdhC Rossmann domain ATPgrasp_Ter PF15632.1 EXF79791.1 - 0.0084 14.8 0.0 0.041 12.6 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon PrpR_N PF06506.6 EXF79791.1 - 0.025 13.9 0.2 0.28 10.5 0.0 2.3 2 0 0 2 2 2 0 Propionate catabolism activator Dus PF01207.12 EXF79792.1 - 2.8e-32 111.7 0.0 1.1e-28 99.9 0.0 2.4 2 1 0 2 2 2 2 Dihydrouridine synthase (Dus) Cyclin_N PF00134.18 EXF79793.1 - 4.3e-08 32.7 0.7 0.00028 20.4 0.5 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain Glyco_hydro_88 PF07470.8 EXF79793.1 - 0.058 12.4 0.4 0.082 11.9 0.2 1.1 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 TFIIB PF00382.14 EXF79793.1 - 0.15 11.8 0.2 0.29 10.9 0.1 1.4 1 0 0 1 1 1 0 Transcription factor TFIIB repeat Proteasome PF00227.21 EXF79794.1 - 7.7e-48 162.2 0.1 9.2e-48 162.0 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit DUF554 PF04474.7 EXF79794.1 - 0.0022 17.2 0.1 0.0031 16.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF554) DUF3222 PF11519.3 EXF79794.1 - 0.031 14.2 0.6 6.4 6.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3222) Peptidase_M22 PF00814.20 EXF79795.1 - 3.7e-44 151.2 0.6 1.2e-16 60.9 0.3 4.1 3 1 1 4 4 4 4 Glycoprotease family YycC PF14174.1 EXF79795.1 - 0.037 13.6 0.0 0.075 12.7 0.0 1.5 1 0 0 1 1 1 0 YycC-like protein Glyco_transf_34 PF05637.7 EXF79797.1 - 5.2e-64 216.0 1.3 6.8e-64 215.6 0.9 1.1 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family Glyco_hydro_16 PF00722.16 EXF79798.1 - 3.6e-10 39.4 0.2 1.2e-09 37.7 0.0 1.9 1 1 1 2 2 2 1 Glycosyl hydrolases family 16 Adeno_shaft PF00608.12 EXF79798.1 - 0.082 12.5 0.2 0.27 10.9 0.2 1.9 1 0 0 1 1 1 0 Adenoviral fibre protein (repeat/shaft region) SNF2_N PF00176.18 EXF79799.1 - 1.1e-32 113.0 0.1 4.4e-31 107.8 0.0 2.2 2 0 0 2 2 2 2 SNF2 family N-terminal domain DEAD PF00270.24 EXF79799.1 - 6.1e-07 29.0 0.0 2.5e-06 27.0 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF79799.1 - 0.00044 20.0 0.2 0.0018 18.1 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain LRR_4 PF12799.2 EXF79801.1 - 1.6e-06 27.5 0.4 0.072 12.7 0.1 3.0 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EXF79801.1 - 0.0022 17.6 8.1 0.53 10.0 0.7 3.6 4 0 0 4 4 4 2 Leucine rich repeat F-box-like PF12937.2 EXF79801.1 - 0.015 15.0 0.2 0.04 13.6 0.1 1.8 1 0 0 1 1 1 0 F-box-like TauD PF02668.11 EXF79802.1 - 7e-40 137.3 0.1 1.1e-39 136.6 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EXF79802.1 - 0.062 13.8 0.1 0.062 13.8 0.1 2.3 3 1 0 3 3 3 0 2OG-Fe(II) oxygenase superfamily adh_short_C2 PF13561.1 EXF79803.1 - 6.9e-32 111.1 0.4 8.6e-32 110.8 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EXF79803.1 - 3.5e-22 79.1 1.6 6.3e-22 78.2 1.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF79803.1 - 8e-07 28.8 0.9 1.5e-06 28.0 0.6 1.5 1 1 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EXF79803.1 - 0.01 15.4 1.4 0.03 13.9 0.1 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EXF79803.1 - 0.026 13.6 0.0 0.053 12.6 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Metallophos PF00149.23 EXF79804.1 - 5.8e-42 143.3 0.6 1e-41 142.5 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Cyclase PF04199.8 EXF79805.1 - 1.8e-05 24.5 0.0 2.7e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Neurensin PF14927.1 EXF79806.1 - 0.46 9.8 2.2 2.5 7.4 1.5 1.9 1 1 0 1 1 1 0 Neurensin PepSY_TM PF03929.11 EXF79806.1 - 4.5 7.8 8.6 7.1 7.2 0.7 2.6 2 0 0 2 2 2 0 PepSY-associated TM helix zf-H2C2_2 PF13465.1 EXF79807.1 - 7e-07 29.2 9.9 5.1e-06 26.5 0.9 3.3 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_4 PF13894.1 EXF79807.1 - 5.6e-05 23.1 5.9 0.00024 21.1 0.3 2.9 3 0 0 3 3 3 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF79807.1 - 6.3e-05 23.0 0.5 6.3e-05 23.0 0.4 3.7 3 1 0 3 3 3 1 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EXF79807.1 - 5.3 7.3 9.8 1.3 9.2 0.4 3.2 3 1 0 3 3 3 0 Zinc-finger double-stranded RNA-binding LRR_6 PF13516.1 EXF79808.1 - 3.6e-13 48.0 4.6 0.46 10.7 0.0 8.1 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.2 EXF79808.1 - 5.8e-12 44.9 13.3 0.0042 16.6 0.0 5.8 7 0 0 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EXF79808.1 - 7.6e-06 25.2 4.4 6 7.3 0.0 6.4 6 3 0 6 6 6 2 Leucine Rich Repeat LRR_8 PF13855.1 EXF79808.1 - 0.00032 20.3 10.4 2.5 7.9 0.0 4.9 3 3 0 3 3 3 3 Leucine rich repeat LRR_7 PF13504.1 EXF79808.1 - 0.0017 18.2 2.3 84 4.0 0.0 6.0 6 0 0 6 6 6 0 Leucine rich repeat LETM1 PF07766.8 EXF79808.1 - 0.023 13.7 0.0 0.023 13.7 0.0 1.7 2 0 0 2 2 2 0 LETM1-like protein Myc_N PF01056.13 EXF79808.1 - 0.03 13.4 2.8 0.046 12.8 2.0 1.3 1 0 0 1 1 1 0 Myc amino-terminal region DUF4504 PF14953.1 EXF79808.1 - 0.046 13.0 0.2 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4504) DUF2567 PF10821.3 EXF79809.1 - 0.0037 16.8 4.8 0.14 11.6 1.2 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2567) DUF4044 PF13253.1 EXF79809.1 - 0.4 9.8 2.5 1.3 8.2 1.7 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Glyco_hydro_18 PF00704.23 EXF79810.1 - 6.1e-98 328.4 9.3 7.5e-98 328.1 6.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Fungal_trans PF04082.13 EXF79811.1 - 1.4e-18 66.6 0.1 2.8e-18 65.7 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Alpha-amylase PF00128.19 EXF79812.1 - 4.2e-63 213.6 0.0 5.7e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EXF79812.1 - 4.7e-22 77.8 0.0 8.5e-22 77.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) NuA4 PF09340.5 EXF79814.1 - 7e-23 80.0 1.3 9.7e-23 79.6 0.0 1.7 2 0 0 2 2 2 1 Histone acetyltransferase subunit NuA4 Med3 PF11593.3 EXF79814.1 - 0.48 9.6 8.5 0.12 11.6 3.8 1.5 1 1 1 2 2 2 0 Mediator complex subunit 3 fungal Peptidase_S9 PF00326.16 EXF79815.1 - 7.9e-54 182.1 0.0 1.5e-53 181.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EXF79815.1 - 9e-10 38.4 0.0 1.6e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF79815.1 - 1.2e-06 28.5 0.1 3.8e-06 26.9 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family PD40 PF07676.7 EXF79815.1 - 0.00053 19.5 0.0 0.0061 16.2 0.0 2.6 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat AXE1 PF05448.7 EXF79815.1 - 0.091 11.2 0.1 0.32 9.4 0.1 1.8 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) Bromo_TP PF07524.8 EXF79816.1 - 3.1e-06 26.8 0.0 6.3e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Bromodomain associated Ribosomal_60s PF00428.14 EXF79816.1 - 0.013 15.8 7.0 0.26 11.6 2.0 3.0 3 0 0 3 3 3 0 60s Acidic ribosomal protein TPT PF03151.11 EXF79817.1 - 1.5e-32 112.3 11.1 1.5e-32 112.3 7.7 2.5 4 0 0 4 4 4 1 Triose-phosphate Transporter family SHOCT PF09851.4 EXF79817.1 - 0.11 11.9 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Short C-terminal domain EamA PF00892.15 EXF79817.1 - 0.24 11.4 33.0 1.3 9.0 4.9 2.9 2 1 0 2 2 2 0 EamA-like transporter family Zip PF02535.17 EXF79817.1 - 5 6.0 9.6 25 3.7 0.0 3.3 3 0 0 3 3 3 0 ZIP Zinc transporter Glyco_hydro_15 PF00723.16 EXF79818.1 - 8.9e-51 172.8 0.0 5.8e-46 156.9 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 IL10 PF00726.12 EXF79818.1 - 0.055 12.7 0.1 0.42 9.8 0.1 2.0 2 0 0 2 2 2 0 Interleukin 10 RRM_1 PF00076.17 EXF79819.1 - 3.5e-17 61.7 0.0 5.8e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF79819.1 - 1e-11 44.6 0.0 1.7e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF79819.1 - 0.00026 20.7 0.0 0.00045 20.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EXF79819.1 - 0.11 11.9 0.2 0.23 10.9 0.2 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain 6PGD PF00393.14 EXF79821.1 - 2.9e-135 450.0 0.0 4.9e-135 449.3 0.0 1.3 2 0 0 2 2 2 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EXF79821.1 - 1.2e-50 171.5 0.0 1.7e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase DNA_pol3_beta PF00712.14 EXF79821.1 - 0.019 14.8 0.0 0.045 13.6 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III beta subunit, N-terminal domain NAD_binding_11 PF14833.1 EXF79821.1 - 0.027 14.5 0.0 0.08 13.0 0.0 1.8 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PGK PF00162.14 EXF79821.1 - 0.04 12.4 0.0 0.062 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase 3HCDH_N PF02737.13 EXF79821.1 - 0.13 11.8 0.5 0.98 9.0 0.1 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SWI-SNF_Ssr4 PF08549.5 EXF79822.1 - 1.1e-187 625.4 15.2 1.6e-187 624.9 10.5 1.1 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) GPI-anchored PF10342.4 EXF79823.1 - 1e-07 32.3 0.0 2.6e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Glutaredoxin PF00462.19 EXF79824.1 - 8.9e-19 67.2 0.0 4.7e-18 64.9 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EXF79824.1 - 4.6e-14 51.9 0.0 1.1e-13 50.8 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EXF79824.1 - 0.022 14.8 0.0 6.1 7.0 0.0 2.6 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_2 PF13098.1 EXF79824.1 - 0.036 14.2 0.0 1.3 9.2 0.0 3.0 2 2 1 3 3 3 0 Thioredoxin-like domain HyaE PF07449.6 EXF79824.1 - 0.06 13.2 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.1 EXF79824.1 - 0.1 12.4 0.0 0.87 9.4 0.0 2.4 2 0 0 2 2 2 0 Thioredoxin domain TrbC_Ftype PF09673.5 EXF79824.1 - 0.12 11.9 0.0 0.92 9.1 0.0 2.4 3 0 0 3 3 3 0 Type-F conjugative transfer system pilin assembly protein SH3_9 PF14604.1 EXF79825.1 - 9.2e-31 105.1 3.8 1.7e-14 53.1 0.2 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EXF79825.1 - 4.5e-26 89.9 5.1 1.6e-12 46.5 0.3 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EXF79825.1 - 3e-17 61.8 0.0 1.8e-07 30.5 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain Cofilin_ADF PF00241.15 EXF79825.1 - 2.2e-10 40.5 0.0 3.6e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein NPP1 PF05630.6 EXF79826.1 - 1.3e-37 129.5 0.0 1.9e-37 129.0 0.0 1.2 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) adh_short PF00106.20 EXF79827.1 - 2.7e-06 27.3 0.4 3.7e-06 26.9 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF79827.1 - 0.00025 20.7 0.2 0.00038 20.1 0.2 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EXF79827.1 - 0.017 15.2 0.0 0.028 14.5 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase p450 PF00067.17 EXF79828.1 - 5.7e-26 91.0 0.0 4.1e-25 88.2 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 DUF521 PF04412.8 EXF79829.1 - 4e-94 315.4 0.0 5.2e-94 315.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF521) DUF126 PF01989.11 EXF79829.1 - 1.1e-28 98.7 0.2 2.1e-28 97.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF126 B PF02216.11 EXF79831.1 - 0.14 11.9 0.6 2.2 8.1 0.1 2.3 2 0 0 2 2 2 0 B domain Lipase_GDSL_2 PF13472.1 EXF79832.1 - 3.5e-13 50.0 0.0 4.4e-13 49.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EXF79832.1 - 6.9e-10 39.1 0.1 8.2e-09 35.6 0.1 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase MFS_1 PF07690.11 EXF79833.1 - 2.7e-30 105.2 20.9 2.7e-30 105.2 14.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily RseC_MucC PF04246.7 EXF79833.1 - 0.00056 19.4 1.5 0.58 9.7 0.0 3.0 1 1 0 2 2 2 2 Positive regulator of sigma(E), RseC/MucC MerC PF03203.9 EXF79833.1 - 0.35 11.2 11.2 0.06 13.7 1.5 3.4 3 1 1 4 4 4 0 MerC mercury resistance protein NfeD PF01957.13 EXF79833.1 - 8.2 6.5 13.7 6.7 6.8 1.0 3.9 2 1 2 4 4 4 0 NfeD-like C-terminal, partner-binding MRJP PF03022.11 EXF79834.1 - 2.2e-10 40.2 0.0 3.1e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Major royal jelly protein NHL PF01436.16 EXF79834.1 - 0.00054 19.7 0.5 0.026 14.4 0.1 2.8 2 0 0 2 2 2 1 NHL repeat SGL PF08450.7 EXF79834.1 - 0.004 16.5 0.9 0.39 10.0 0.0 2.6 2 1 0 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region LVIVD PF08309.6 EXF79834.1 - 0.056 12.4 0.4 0.15 11.0 0.2 1.7 1 0 0 1 1 1 0 LVIVD repeat SNF PF00209.13 EXF79835.1 - 3.9e-80 269.7 31.4 3.9e-80 269.7 21.8 2.6 2 1 0 2 2 2 1 Sodium:neurotransmitter symporter family DUF1446 PF07287.6 EXF79836.1 - 6e-120 400.0 0.1 7.1e-120 399.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) Hemerythrin PF01814.18 EXF79837.1 - 1.8e-07 31.3 0.4 2.4e-07 30.9 0.3 1.2 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF2383 PF09537.5 EXF79837.1 - 0.0034 17.6 0.0 0.0059 16.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2383) Zip PF02535.17 EXF79838.1 - 0.18 10.7 4.1 0.22 10.4 2.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SelP_N PF04592.9 EXF79838.1 - 0.9 8.8 6.1 1.3 8.3 4.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Chorion_2 PF03964.10 EXF79838.1 - 7.3 7.1 16.9 1.9e+03 -0.6 11.7 2.7 1 1 0 1 1 1 0 Chorion family 2 Glyco_hydro_61 PF03443.9 EXF79839.1 - 6e-63 212.5 0.3 6.8e-63 212.3 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 AsnA PF03590.10 EXF79839.1 - 0.15 11.5 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Aspartate-ammonia ligase BNR PF02012.15 EXF79841.1 - 8e-13 46.1 27.7 0.081 12.7 0.1 9.5 9 0 0 9 9 9 6 BNR/Asp-box repeat GMC_oxred_N PF00732.14 EXF79842.1 - 1.6e-60 204.7 0.0 2.1e-60 204.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF79842.1 - 1.5e-39 135.5 0.2 2.8e-39 134.6 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EXF79842.1 - 1.1e-05 24.5 0.0 0.019 13.8 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EXF79842.1 - 9e-05 21.5 0.0 0.00082 18.3 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF79842.1 - 0.00033 19.7 0.1 0.00049 19.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EXF79842.1 - 0.00057 19.8 0.1 0.0014 18.5 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF79842.1 - 0.001 18.9 0.2 0.0024 17.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF79842.1 - 0.0012 18.0 0.2 0.0034 16.5 0.1 1.7 2 0 0 2 2 2 1 Thi4 family Pyr_redox_3 PF13738.1 EXF79842.1 - 0.0056 16.7 0.3 1.6 8.7 0.2 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF79842.1 - 0.044 12.2 0.1 0.08 11.4 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein NAD_binding_9 PF13454.1 EXF79842.1 - 0.077 12.7 0.3 0.2 11.4 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EXF79842.1 - 0.09 11.3 0.4 0.15 10.6 0.1 1.4 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_8 PF13450.1 EXF79843.1 - 4.4e-12 45.8 0.2 9.4e-12 44.7 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EXF79843.1 - 2e-07 30.4 0.0 2.4e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EXF79843.1 - 1.9e-06 28.0 0.0 0.0004 20.4 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF79843.1 - 1.1e-05 24.5 0.0 5.6e-05 22.1 0.0 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF79843.1 - 0.00016 20.6 0.4 0.00027 19.9 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EXF79843.1 - 0.00045 20.1 0.0 0.00081 19.3 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF79843.1 - 0.00073 18.7 0.2 0.0012 17.9 0.1 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EXF79843.1 - 0.00073 18.1 0.2 0.0011 17.4 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 EXF79843.1 - 0.0011 18.1 0.0 0.0016 17.5 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF79843.1 - 0.05 12.5 0.3 0.13 11.1 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.22 EXF79843.1 - 0.1 12.9 0.1 0.27 11.6 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF79843.1 - 0.12 11.2 0.4 0.17 10.6 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Tannase PF07519.6 EXF79845.1 - 6.7e-113 377.8 0.9 1e-112 377.2 0.7 1.3 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_5 PF12695.2 EXF79845.1 - 2.1e-05 24.2 0.1 0.029 14.1 0.0 2.3 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF79845.1 - 0.00027 20.5 0.0 0.00078 19.0 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EXF79845.1 - 0.0026 17.6 0.0 0.0052 16.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family p450 PF00067.17 EXF79846.1 - 2.8e-24 85.4 0.0 3.6e-20 71.9 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Esterase_phd PF10503.4 EXF79847.1 - 7.1e-22 77.7 1.6 1.2e-21 76.9 1.1 1.3 1 0 0 1 1 1 1 Esterase PHB depolymerase CBM_1 PF00734.13 EXF79847.1 - 9.2e-15 54.0 8.0 3.8e-14 52.0 5.5 2.2 1 0 0 1 1 1 1 Fungal cellulose binding domain Peptidase_S9 PF00326.16 EXF79847.1 - 6.1e-11 41.9 3.8 1e-10 41.2 2.7 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EXF79847.1 - 4.5e-06 26.4 0.2 7.2e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF79847.1 - 3.1e-05 23.6 0.1 5.4e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EXF79847.1 - 0.00042 20.2 0.1 0.00062 19.7 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EXF79847.1 - 0.021 14.2 0.2 0.034 13.5 0.1 1.3 1 0 0 1 1 1 0 Putative esterase DUF2235 PF09994.4 EXF79847.1 - 0.033 13.5 0.3 0.042 13.2 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) Aa_trans PF01490.13 EXF79848.1 - 1e-82 277.8 18.3 1.2e-82 277.5 12.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Claudin_2 PF13903.1 EXF79848.1 - 0.011 15.4 5.9 0.035 13.7 1.3 3.1 3 1 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction Troponin-I_N PF11636.3 EXF79848.1 - 0.26 10.9 1.0 0.54 10.0 0.7 1.4 1 0 0 1 1 1 0 Troponin I residues 1-32 CAAD PF14159.1 EXF79848.1 - 9.2 5.9 9.4 0.26 10.9 0.8 2.9 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Ecl1 PF12855.2 EXF79849.1 - 0.0027 16.9 0.9 0.0064 15.7 0.6 1.6 1 0 0 1 1 1 1 Life-span regulatory factor tRNA-synt_1g PF09334.6 EXF79849.1 - 0.12 10.9 0.8 0.17 10.5 0.5 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (M) DUF2256 PF10013.4 EXF79849.1 - 0.24 11.2 5.5 1.1 9.1 1.5 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) An_peroxidase PF03098.10 EXF79852.1 - 2e-87 293.7 0.0 9.8e-69 232.1 0.0 2.2 1 1 1 2 2 2 2 Animal haem peroxidase p450 PF00067.17 EXF79852.1 - 1.6e-07 30.2 0.0 5.7e-07 28.4 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 DUF2235 PF09994.4 EXF79853.1 - 6.9e-73 245.3 5.9 2.4e-70 237.0 4.1 3.0 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Amidase PF01425.16 EXF79854.1 - 4.2e-22 78.5 8.6 2e-20 73.0 6.0 2.2 1 1 0 1 1 1 1 Amidase Tautomerase_3 PF14832.1 EXF79854.1 - 1.6e-07 31.4 0.0 5.6e-07 29.6 0.0 1.8 2 0 0 2 2 2 1 Putative oxalocrotonate tautomerase enzyme p450 PF00067.17 EXF79855.1 - 5.8e-41 140.4 0.0 7.1e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 PGG PF13962.1 EXF79856.1 - 0.096 12.3 0.2 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function COesterase PF00135.23 EXF79857.1 - 1.5e-90 304.5 0.1 2.1e-90 303.9 0.1 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF79857.1 - 8.7e-08 31.9 0.1 4.1e-07 29.8 0.0 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EXF79857.1 - 0.00015 21.0 3.3 0.0004 19.6 2.3 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EXF79857.1 - 0.012 15.3 0.1 0.022 14.5 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family ADH_zinc_N PF00107.21 EXF79859.1 - 3.1e-27 94.6 0.1 5.3e-27 93.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF79859.1 - 1.7e-20 74.1 0.0 5.1e-20 72.6 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF79859.1 - 1.4e-09 37.6 0.0 2.9e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EXF79859.1 - 0.026 14.0 0.1 0.045 13.3 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 EXF79860.1 - 1.2e-93 314.1 0.8 1.6e-93 313.8 0.6 1.0 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EXF79860.1 - 7.1e-07 28.5 0.1 2.5e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EXF79860.1 - 4.2e-06 26.6 0.1 1.6e-05 24.8 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF79860.1 - 6.3e-05 22.9 0.1 0.0016 18.3 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF79860.1 - 8.3e-05 22.7 0.0 0.00081 19.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF79860.1 - 8.3e-05 21.6 3.8 0.00036 19.5 0.3 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EXF79860.1 - 0.00026 19.9 0.1 0.00026 19.9 0.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Thi4 PF01946.12 EXF79860.1 - 0.00034 19.7 0.2 0.0012 17.9 0.1 1.8 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 EXF79860.1 - 0.0013 17.8 0.0 0.0024 16.9 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EXF79860.1 - 0.0021 16.6 7.5 0.005 15.3 0.2 2.4 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox PF00070.22 EXF79860.1 - 0.011 16.1 0.3 0.97 9.8 0.2 3.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF79860.1 - 0.039 13.7 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EXF79860.1 - 0.05 12.5 0.2 0.078 11.8 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein DUF3273 PF11677.3 EXF79861.1 - 0.0088 15.3 5.4 0.0095 15.2 1.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3273) TMEM247 PF15444.1 EXF79861.1 - 0.086 12.6 0.5 0.13 12.1 0.3 1.2 1 0 0 1 1 1 0 Transmembrane protein 247 Fungal_trans PF04082.13 EXF79862.1 - 1.1e-20 73.6 0.4 2.1e-20 72.7 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ATP-grasp_4 PF13535.1 EXF79862.1 - 3e-13 49.9 0.0 5.3e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EXF79862.1 - 4.6e-07 29.4 0.0 7.3e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Zn_clus PF00172.13 EXF79862.1 - 2.7e-06 27.1 7.4 5e-06 26.3 5.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ATPgrasp_Ter PF15632.1 EXF79862.1 - 1.8e-05 23.6 0.0 4.8e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.14 EXF79862.1 - 0.0085 15.6 0.0 0.013 15.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_3 PF02655.9 EXF79862.1 - 0.0089 15.9 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EXF79862.1 - 0.018 14.3 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.6 EXF79862.1 - 0.071 12.5 0.0 0.12 11.8 0.0 1.3 1 0 0 1 1 1 0 RimK-like ATP-grasp domain SGL PF08450.7 EXF79865.1 - 1e-27 97.0 0.1 1.4e-27 96.6 0.1 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EXF79865.1 - 5.5e-05 23.0 0.0 0.00018 21.4 0.0 1.9 2 0 0 2 2 2 1 Arylesterase Str_synth PF03088.11 EXF79865.1 - 0.00013 21.9 0.0 0.00029 20.8 0.0 1.7 1 0 0 1 1 1 1 Strictosidine synthase NHL PF01436.16 EXF79865.1 - 0.012 15.5 1.5 1.8 8.6 0.0 4.3 4 0 0 4 4 4 0 NHL repeat Hexapep_2 PF14602.1 EXF79866.1 - 5.4e-15 54.6 7.2 6.7e-11 41.5 2.6 3.1 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.19 EXF79866.1 - 5.7e-15 54.0 9.3 2.3e-10 39.4 3.0 3.3 3 0 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Mac PF12464.3 EXF79866.1 - 3.5e-09 36.5 0.0 5.5e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Tmemb_170 PF10190.4 EXF79867.1 - 3.9e-05 23.6 11.2 5.1e-05 23.2 7.8 1.1 1 0 0 1 1 1 1 Putative transmembrane protein 170 bZIP_1 PF00170.16 EXF79870.1 - 1.1e-05 25.2 7.6 1.1e-05 25.2 5.3 1.7 2 0 0 2 2 2 1 bZIP transcription factor DUF4407 PF14362.1 EXF79870.1 - 0.51 9.2 3.1 0.79 8.6 2.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) bZIP_2 PF07716.10 EXF79870.1 - 4.6 7.1 11.0 0.86 9.4 4.6 2.0 2 0 0 2 2 2 0 Basic region leucine zipper Chitin_bind_1 PF00187.14 EXF79875.1 - 4.6e-11 42.5 38.5 3.2e-10 39.8 9.0 2.9 1 1 1 2 2 2 2 Chitin recognition protein LysM PF01476.15 EXF79876.1 - 2.6e-16 59.2 0.4 7.6e-07 28.9 0.0 6.5 6 0 0 6 6 6 5 LysM domain Peptidase_M20 PF01546.23 EXF79878.1 - 8.6e-27 93.8 0.1 1.2e-26 93.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EXF79878.1 - 0.0018 17.9 0.0 0.0043 16.7 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EXF79878.1 - 0.0061 16.3 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M28 MFS_1 PF07690.11 EXF79879.1 - 1.3e-37 129.3 28.6 1.3e-37 129.3 19.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 EXF79880.1 - 2.7e-14 52.6 1.2 5.2e-14 51.7 0.8 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EXF79881.1 - 0.043 12.6 0.0 0.08 11.8 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain bZIP_1 PF00170.16 EXF79882.1 - 0.00016 21.5 9.0 0.0003 20.6 6.2 1.4 1 0 0 1 1 1 1 bZIP transcription factor Lactonase PF10282.4 EXF79883.1 - 6.9e-05 22.0 0.0 0.0041 16.2 0.0 2.4 2 1 0 2 2 2 2 Lactonase, 7-bladed beta-propeller NHL PF01436.16 EXF79883.1 - 0.024 14.6 0.2 2.5 8.1 0.0 3.5 4 0 0 4 4 4 0 NHL repeat Aa_trans PF01490.13 EXF79884.1 - 5.9e-29 100.7 35.5 6.8e-29 100.5 24.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AA_permease_2 PF13520.1 EXF79884.1 - 0.049 12.1 47.0 0.1 11.0 26.7 2.7 1 1 1 2 2 2 0 Amino acid permease DUF872 PF05915.7 EXF79884.1 - 4.9 7.0 7.2 27 4.6 1.3 2.9 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Polysacc_deac_1 PF01522.16 EXF79885.1 - 7.5e-22 77.2 0.0 1.3e-21 76.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EXF79885.1 - 0.041 13.2 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2334) ADH_N PF08240.7 EXF79886.1 - 5.1e-22 77.7 0.6 1.3e-21 76.3 0.1 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF79886.1 - 6.4e-19 67.7 0.1 1.1e-18 67.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EXF79886.1 - 0.0031 16.6 0.0 0.0051 15.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TGS PF02824.16 EXF79886.1 - 0.07 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 TGS domain ThiF PF00899.16 EXF79886.1 - 0.074 12.8 1.6 0.76 9.5 0.7 2.2 2 0 0 2 2 2 0 ThiF family XdhC_C PF13478.1 EXF79886.1 - 0.13 12.5 0.1 0.33 11.2 0.0 1.7 2 0 0 2 2 2 0 XdhC Rossmann domain Amidase PF01425.16 EXF79887.1 - 1.5e-90 304.2 0.2 2e-90 303.7 0.1 1.1 1 0 0 1 1 1 1 Amidase MSP1b PF03429.8 EXF79887.1 - 0.089 10.6 0.0 0.13 10.0 0.0 1.2 1 0 0 1 1 1 0 Major surface protein 1B Zn_clus PF00172.13 EXF79888.1 - 5.6e-07 29.3 10.0 1e-06 28.5 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF79888.1 - 0.00024 19.8 0.1 0.00035 19.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short_C2 PF13561.1 EXF79889.1 - 2.4e-27 96.2 0.1 2.7e-27 96.0 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EXF79889.1 - 1.1e-20 74.2 0.6 1.7e-20 73.5 0.2 1.5 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EXF79889.1 - 3.9e-08 33.1 0.9 5.5e-08 32.6 0.1 1.6 2 0 0 2 2 2 1 KR domain ThiF PF00899.16 EXF79889.1 - 0.016 15.0 1.7 0.11 12.3 0.7 2.5 2 1 1 3 3 3 0 ThiF family SIS PF01380.17 EXF79889.1 - 0.083 12.5 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 SIS domain Fungal_trans PF04082.13 EXF79890.1 - 6.7e-12 44.8 0.2 1.6e-11 43.5 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain UPF0547 PF10571.4 EXF79890.1 - 0.22 11.2 1.1 0.45 10.2 0.7 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 zf-C2H2 PF00096.21 EXF79890.1 - 0.48 10.8 5.9 0.27 11.6 0.2 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF79890.1 - 0.57 10.6 5.7 0.77 10.2 0.1 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Cofilin_ADF PF00241.15 EXF79891.1 - 4.7e-27 94.3 0.0 1.9e-13 50.3 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Mito_carr PF00153.22 EXF79892.1 - 1.4e-62 207.4 2.2 6.1e-23 80.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein WD40 PF00400.27 EXF79893.1 - 4.3e-61 200.7 13.9 1.6e-10 40.4 0.3 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EXF79893.1 - 4.9e-15 54.6 0.4 0.0044 15.2 0.0 4.2 2 1 1 4 4 4 4 Nucleoporin Nup120/160 F-box-like PF12937.2 EXF79893.1 - 3.2e-13 49.1 0.1 6.4e-13 48.2 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EXF79893.1 - 9.3e-10 37.9 0.0 2.1e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.1 EXF79893.1 - 0.0058 16.3 0.0 1.8 8.3 0.0 3.8 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region His_Phos_2 PF00328.17 EXF79894.1 - 8.1e-14 51.7 1.0 4.1e-11 42.8 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Glyco_hydro_61 PF03443.9 EXF79895.1 - 7.9e-69 231.7 0.2 1.4e-68 230.9 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Tyrosinase PF00264.15 EXF79897.1 - 3.5e-23 82.9 1.6 1.2e-22 81.2 0.6 1.8 1 1 1 2 2 2 1 Common central domain of tyrosinase DUF3144 PF11342.3 EXF79898.1 - 0.018 15.0 0.0 0.022 14.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3144) FA_desaturase PF00487.19 EXF79899.1 - 0.64 9.4 9.2 0.013 14.9 1.1 1.8 2 0 0 2 2 2 0 Fatty acid desaturase SET PF00856.23 EXF79900.1 - 5e-08 33.4 2.0 1.4e-07 32.0 0.0 2.6 2 1 0 2 2 2 1 SET domain Ribosomal_L14 PF00238.14 EXF79901.1 - 2.9e-43 146.5 1.7 3.2e-43 146.3 1.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e RNA_POL_M_15KD PF02150.11 EXF79902.1 - 3.7e-11 42.5 2.8 3.7e-11 42.5 2.0 2.2 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit zf-C3HC4_3 PF13920.1 EXF79902.1 - 0.027 14.1 0.8 0.027 14.1 0.5 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 EXF79902.1 - 0.12 12.2 7.2 11 6.0 5.0 2.3 1 1 0 1 1 1 0 IBR domain DZR PF12773.2 EXF79902.1 - 0.41 10.5 12.5 0.18 11.6 2.5 2.7 2 1 0 2 2 2 0 Double zinc ribbon GFA PF04828.9 EXF79902.1 - 2.3 8.2 8.7 0.91 9.5 1.4 2.5 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-NADH-PPase PF09297.6 EXF79902.1 - 2.8 7.5 6.8 18 4.9 0.0 3.0 2 1 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-C3HC4_2 PF13923.1 EXF79902.1 - 5.6 7.0 13.1 0.13 12.3 0.7 2.8 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Rotamase PF00639.16 EXF79903.1 - 4.2e-22 78.6 0.0 5.8e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EXF79903.1 - 2.4e-16 60.0 0.0 3e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 PPIC-type PPIASE domain WW PF00397.21 EXF79903.1 - 2.4e-09 36.8 0.4 5e-09 35.8 0.3 1.6 1 0 0 1 1 1 1 WW domain Rotamase_2 PF13145.1 EXF79903.1 - 6.1e-06 26.8 0.0 8.6e-06 26.3 0.0 1.3 1 1 0 1 1 1 1 PPIC-type PPIASE domain DUF4005 PF13178.1 EXF79903.1 - 0.07 13.3 1.1 0.13 12.5 0.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4005) MbtH PF03621.8 EXF79903.1 - 0.085 12.2 0.0 7 6.0 0.0 2.5 2 0 0 2 2 2 0 MbtH-like protein PSP PF04046.11 EXF79903.1 - 0.11 11.9 0.1 4.1 6.8 0.0 2.8 3 0 0 3 3 3 0 PSP LrgB PF04172.11 EXF79904.1 - 2.1e-14 53.2 7.4 1.3e-09 37.4 0.6 2.6 2 1 0 2 2 2 2 LrgB-like family ATP-synt_8 PF00895.15 EXF79904.1 - 0.63 10.2 3.9 0.3 11.3 0.2 2.5 2 0 0 2 2 2 0 ATP synthase protein 8 DUF2029 PF09594.5 EXF79904.1 - 2.7 7.4 20.5 1 8.8 8.4 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF2029) HAUS-augmin3 PF14932.1 EXF79905.1 - 0.0048 16.1 11.0 0.0048 16.1 7.6 3.1 1 1 0 2 2 2 1 HAUS augmin-like complex subunit 3 Cep57_MT_bd PF06657.8 EXF79905.1 - 0.37 10.7 13.0 0.94 9.4 0.5 4.1 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 V_ATPase_I PF01496.14 EXF79905.1 - 0.9 7.3 7.0 1.7 6.4 4.9 1.5 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.10 EXF79905.1 - 1.6 8.2 12.6 4.3 6.8 1.6 3.7 2 1 1 3 3 3 0 Septum formation initiator Dna2 PF08696.6 EXF79905.1 - 2.2 7.5 7.7 16 4.7 0.1 2.9 1 1 2 3 3 3 0 DNA replication factor Dna2 Allexi_40kDa PF05549.6 EXF79905.1 - 6.8 5.8 17.4 1.9 7.7 4.8 2.9 1 1 2 3 3 3 0 Allexivirus 40kDa protein Sugar_tr PF00083.19 EXF79906.1 - 7.2e-86 288.5 23.2 8.4e-86 288.3 16.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF79906.1 - 9.3e-18 64.0 41.8 5.3e-12 45.1 9.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M24 PF00557.19 EXF79908.1 - 1.1e-49 168.8 0.1 1.5e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EXF79908.1 - 3.1e-28 97.8 0.0 8.2e-28 96.4 0.0 1.7 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Peptidase_C12 PF01088.16 EXF79909.1 - 3.8e-54 183.1 0.0 4.4e-54 182.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 NicO PF03824.11 EXF79910.1 - 2e-65 220.9 6.8 3.1e-65 220.2 4.7 1.3 1 0 0 1 1 1 1 High-affinity nickel-transport protein Peptidase_C2 PF00648.16 EXF79912.1 - 1.7e-51 174.9 0.9 2.6e-35 121.8 0.3 2.7 2 0 0 2 2 2 2 Calpain family cysteine protease FAD_binding_2 PF00890.19 EXF79913.1 - 2.1e-81 273.8 0.2 2.6e-81 273.6 0.2 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF79913.1 - 1.3e-08 34.1 0.2 8.3e-06 24.9 0.1 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF79913.1 - 7.2e-08 32.5 0.0 0.00018 21.4 0.3 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EXF79913.1 - 1.1e-06 28.0 0.6 1.8e-06 27.3 0.4 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EXF79913.1 - 1.3e-05 24.4 1.5 0.00046 19.3 0.3 2.3 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EXF79913.1 - 0.00012 22.0 2.9 0.00031 20.6 2.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EXF79913.1 - 0.00015 20.3 1.4 0.00015 20.3 1.0 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EXF79913.1 - 0.0012 18.9 0.7 0.032 14.2 0.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EXF79913.1 - 0.032 13.2 0.8 0.049 12.6 0.6 1.2 1 0 0 1 1 1 0 FAD binding domain UPF0227 PF05728.7 EXF79913.1 - 0.072 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) GIDA PF01134.17 EXF79913.1 - 0.78 8.5 3.3 7.6 5.2 1.4 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A MFS_1 PF07690.11 EXF79914.1 - 4.5e-18 65.0 20.1 4.5e-18 65.0 13.9 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily Glyco_transf_52 PF07922.6 EXF79914.1 - 0.092 11.7 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 52 DUF4201 PF13870.1 EXF79916.1 - 0.00033 20.1 1.5 0.00033 20.1 1.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) Fungal_trans PF04082.13 EXF79917.1 - 0.00043 19.2 0.5 0.00073 18.4 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Git3 PF11710.3 EXF79918.1 - 3.8e-06 26.5 7.8 0.043 13.3 4.0 2.9 2 1 0 2 2 2 2 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 EXF79918.1 - 0.00041 19.5 1.5 0.016 14.3 0.9 2.6 3 1 0 3 3 3 1 7 transmembrane receptor (rhodopsin family) WBP-1 PF11669.3 EXF79918.1 - 0.052 13.6 0.5 0.14 12.2 0.3 1.7 1 0 0 1 1 1 0 WW domain-binding protein 1 DNA_ligase_A_C PF04679.10 EXF79919.1 - 0.0085 16.4 0.0 0.021 15.2 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region 2OG-FeII_Oxy PF03171.15 EXF79920.1 - 5.7e-23 81.0 0.0 1.9e-22 79.4 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EXF79920.1 - 7.1e-23 81.3 0.0 1.2e-22 80.5 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Peptidase_M35 PF02102.10 EXF79921.1 - 7.8e-69 232.0 3.7 9.7e-69 231.7 2.6 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EXF79921.1 - 2.9e-08 34.3 0.1 5.6e-08 33.4 0.1 1.5 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase GFO_IDH_MocA PF01408.17 EXF79922.1 - 4.8e-18 65.8 0.0 7.1e-18 65.2 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Sugar_tr PF00083.19 EXF79923.1 - 2.9e-84 283.2 19.0 3.4e-84 283.0 13.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF79923.1 - 3.2e-32 111.6 49.0 1.2e-24 86.6 16.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF79923.1 - 0.0059 14.8 0.3 0.0059 14.8 0.2 2.8 3 0 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) NfeD PF01957.13 EXF79923.1 - 0.44 10.6 0.0 0.44 10.6 0.0 2.9 3 1 1 4 4 4 0 NfeD-like C-terminal, partner-binding GFO_IDH_MocA PF01408.17 EXF79924.1 - 3.4e-18 66.3 0.0 1.1e-17 64.6 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EXF79924.1 - 0.011 16.1 0.1 0.019 15.3 0.0 1.4 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain Methyltransf_25 PF13649.1 EXF79924.1 - 0.02 15.2 0.1 0.052 13.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EXF79924.1 - 0.14 12.6 0.1 0.48 10.9 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain PAN_1 PF00024.21 EXF79925.1 - 2e-11 43.4 23.1 7.6e-06 25.5 0.9 4.7 3 1 1 4 4 4 3 PAN domain PAN_4 PF14295.1 EXF79925.1 - 9.1e-08 31.6 28.3 0.00081 19.0 0.6 5.0 4 1 0 4 4 4 3 PAN domain DUF814 PF05670.8 EXF79925.1 - 0.099 12.5 0.1 0.35 10.7 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF814) Sporozoite_P67 PF05642.6 EXF79925.1 - 1.2 6.9 14.1 2.5 5.8 9.7 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen MtmB PF05369.7 EXF79926.1 - 0.26 9.4 3.2 0.3 9.2 2.2 1.0 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB Glyco_hydro_43 PF04616.9 EXF79927.1 - 4.6e-13 48.9 6.1 2.8e-11 43.0 1.6 1.6 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 tRNA-synt_1g PF09334.6 EXF79928.1 - 1.3e-134 448.7 1.9 2.2e-76 257.0 0.1 2.4 2 1 1 3 3 3 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EXF79928.1 - 3.9e-08 31.7 5.7 0.0003 18.9 0.0 4.2 4 1 1 5 5 5 3 tRNA synthetases class I (I, L, M and V) EcoEI_R_C PF08463.5 EXF79928.1 - 0.031 14.1 0.2 2.7 7.8 0.1 2.5 2 0 0 2 2 2 0 EcoEI R protein C-terminal DUF3987 PF13148.1 EXF79928.1 - 0.26 9.8 5.3 0.48 8.9 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) 3HCDH_N PF02737.13 EXF79928.1 - 0.43 10.2 7.3 0.86 9.2 5.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NARP1 PF12569.3 EXF79928.1 - 7.9 5.1 13.7 13 4.3 9.5 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 BRF1 PF07741.8 EXF79928.1 - 8.3 6.7 13.7 8.4 6.7 8.1 2.1 2 0 0 2 2 2 0 Brf1-like TBP-binding domain WD40 PF00400.27 EXF79929.1 - 1.2e-07 31.3 5.6 0.75 9.7 0.0 6.4 7 0 0 7 7 7 3 WD domain, G-beta repeat Proteasome_A_N PF10584.4 EXF79929.1 - 0.0004 19.6 0.1 0.55 9.5 0.0 3.5 3 0 0 3 3 3 1 Proteasome subunit A N-terminal signature PD40 PF07676.7 EXF79929.1 - 0.0021 17.7 0.2 3 7.6 0.0 4.4 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat TruB_C PF09142.6 EXF79929.1 - 0.0094 15.5 7.9 0.077 12.6 0.0 4.3 5 0 0 5 5 5 1 tRNA Pseudouridine synthase II, C terminal ADH_N PF08240.7 EXF79930.1 - 3.4e-26 91.1 2.7 6.5e-26 90.2 1.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF79930.1 - 4.6e-15 55.3 0.1 1.3e-14 53.8 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EXF79930.1 - 6.3e-05 22.1 0.2 0.00011 21.3 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.11 EXF79930.1 - 0.022 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA ABA_WDS PF02496.11 EXF79930.1 - 0.17 12.0 0.0 0.42 10.8 0.0 1.6 1 0 0 1 1 1 0 ABA/WDS induced protein WD40 PF00400.27 EXF79932.1 - 4.7e-45 149.9 11.9 2.4e-08 33.5 0.0 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EXF79932.1 - 1.2e-09 37.7 0.1 2.9e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EXF79932.1 - 8.3e-09 34.8 0.0 1.9e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EXF79932.1 - 1e-06 27.2 1.3 0.14 10.2 0.0 3.6 1 1 1 3 3 3 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EXF79932.1 - 0.00026 20.5 0.0 0.0005 19.5 0.0 1.4 1 0 0 1 1 1 1 PQQ-like domain Cytochrom_D1 PF02239.11 EXF79932.1 - 0.0014 16.9 0.0 0.0027 16.0 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain FlaG PF03646.10 EXF79932.1 - 0.15 12.2 0.0 4.1 7.5 0.0 3.2 4 0 0 4 4 4 0 FlaG protein Pectate_lyase_3 PF12708.2 EXF79933.1 - 8.7e-79 264.7 28.6 1.1e-68 231.7 8.7 3.2 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EXF79933.1 - 4.8e-06 25.9 1.1 0.057 12.9 0.0 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Scs3p PF10261.4 EXF79934.1 - 4.3e-63 212.5 5.6 5.8e-63 212.1 3.9 1.2 1 0 0 1 1 1 1 Inositol phospholipid synthesis and fat-storage-inducing TM ATP_transf PF09830.4 EXF79934.1 - 2.5e-15 56.0 0.0 5.2e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 ATP adenylyltransferase Myb_DNA-bind_4 PF13837.1 EXF79935.1 - 0.0033 17.5 0.5 0.0075 16.3 0.0 1.8 2 0 0 2 2 2 1 Myb/SANT-like DNA-binding domain DUF1752 PF08550.5 EXF79936.1 - 9.2e-05 21.9 2.9 0.00018 21.0 2.0 1.4 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) CTP_transf_2 PF01467.21 EXF79938.1 - 1.5e-23 83.6 0.0 1.9e-23 83.2 0.0 1.2 1 0 0 1 1 1 1 Cytidylyltransferase DUF4237 PF14021.1 EXF79938.1 - 0.053 13.7 0.0 0.16 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4237) Pec_lyase_C PF00544.14 EXF79939.1 - 0.00072 19.0 2.4 0.0012 18.4 1.6 1.3 1 0 0 1 1 1 1 Pectate lyase 7tm_2 PF00002.19 EXF79940.1 - 1.2e-10 40.8 9.0 1.2e-10 40.8 6.3 1.6 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 EXF79940.1 - 1.1e-07 31.0 8.2 1.1e-07 31.0 5.7 2.0 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Git3 PF11710.3 EXF79940.1 - 1.7e-06 27.7 9.8 3e-06 26.9 6.8 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Fungal_trans_2 PF11951.3 EXF79941.1 - 0.00078 18.1 0.0 0.0025 16.5 0.0 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 EXF79942.1 - 4.2e-23 82.4 0.3 5.9e-23 81.9 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF79942.1 - 5.1e-10 39.2 0.0 2.1e-09 37.2 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF79942.1 - 3e-09 36.7 0.3 2.8e-08 33.6 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EXF79942.1 - 0.00026 20.7 0.0 0.012 15.3 0.0 2.4 2 0 0 2 2 2 1 Putative lysophospholipase TPR_12 PF13424.1 EXF79943.1 - 5.2e-31 106.4 54.7 5.1e-07 29.5 0.5 12.9 10 3 4 14 14 14 8 Tetratricopeptide repeat Ank_2 PF12796.2 EXF79943.1 - 2.8e-30 104.4 0.7 1.1e-09 38.5 0.0 7.0 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Pkinase PF00069.20 EXF79943.1 - 1.2e-27 96.6 0.0 3.2e-27 95.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF79943.1 - 3.6e-19 68.8 0.0 8.8e-19 67.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_3 PF13606.1 EXF79943.1 - 4.1e-16 57.4 6.9 0.0063 16.6 0.0 10.5 11 1 1 12 12 9 2 Ankyrin repeat Ank PF00023.25 EXF79943.1 - 1.9e-15 55.7 6.1 0.0028 17.3 0.0 8.6 8 1 0 8 8 8 3 Ankyrin repeat Ank_5 PF13857.1 EXF79943.1 - 4.3e-13 49.0 0.1 0.79 10.0 0.0 8.4 8 1 0 8 8 7 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EXF79943.1 - 1.4e-10 41.4 3.3 0.014 15.9 0.0 6.7 6 1 0 6 6 6 3 Ankyrin repeats (many copies) TPR_10 PF13374.1 EXF79943.1 - 5.1e-09 35.7 32.4 1.1 9.2 1.5 13.1 13 0 0 13 13 13 1 Tetratricopeptide repeat TPR_14 PF13428.1 EXF79943.1 - 8.5e-06 25.9 37.5 2.9 8.7 0.1 13.1 11 4 4 15 15 13 3 Tetratricopeptide repeat TPR_11 PF13414.1 EXF79943.1 - 9.5e-06 25.1 25.3 0.11 12.2 1.3 8.1 5 1 4 9 9 9 4 TPR repeat TPR_16 PF13432.1 EXF79943.1 - 2e-05 25.1 29.9 0.7 10.6 0.8 8.6 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 EXF79943.1 - 6.9e-05 23.0 29.6 0.039 14.2 0.1 9.5 9 2 3 12 12 10 1 Tetratricopeptide repeat TPR_2 PF07719.12 EXF79943.1 - 7.2e-05 22.4 37.3 1.6 8.8 0.4 11.9 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_7 PF13176.1 EXF79943.1 - 0.0047 16.6 18.5 13 5.8 0.0 9.9 10 0 0 10 10 9 0 Tetratricopeptide repeat Sel1 PF08238.7 EXF79943.1 - 0.02 15.5 0.0 0.29 11.8 0.0 3.0 2 0 0 2 2 2 0 Sel1 repeat PPR_3 PF13812.1 EXF79943.1 - 0.23 11.8 4.6 61 4.2 0.0 5.8 5 0 0 5 5 4 0 Pentatricopeptide repeat domain TPR_1 PF00515.23 EXF79943.1 - 7.2 6.4 23.4 5.1 6.8 0.4 7.2 8 0 0 8 8 7 0 Tetratricopeptide repeat DUF4238 PF14022.1 EXF79943.1 - 9.9 5.3 7.9 4.7 6.4 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4238) HeLo PF14479.1 EXF79944.1 - 3.7e-10 39.9 0.9 1.3e-09 38.1 0.4 2.0 2 1 0 2 2 2 1 Prion-inhibition and propagation Pkinase PF00069.20 EXF79944.1 - 0.004 16.3 0.0 0.006 15.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF79944.1 - 0.042 12.9 0.0 0.12 11.4 0.0 1.5 1 1 0 1 1 1 0 Protein tyrosine kinase AKAP_110 PF05716.8 EXF79944.1 - 0.043 11.7 0.0 0.061 11.3 0.0 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 110 kDa (AKAP 110) HET PF06985.6 EXF79945.1 - 2.1e-23 82.9 0.1 5.3e-23 81.7 0.1 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 EXF79945.1 - 2.3e-22 79.4 0.0 3.6e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF79945.1 - 1.1e-14 54.0 0.0 2e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EXF79945.1 - 0.12 11.0 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 EXF79946.1 - 5.6e-14 51.9 0.0 1e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF79946.1 - 0.00023 20.3 0.0 0.00092 18.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EXF79948.1 - 1.8e-27 96.1 0.0 4.6e-24 84.9 0.0 3.3 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EXF79948.1 - 1.4e-14 53.8 0.0 1.8e-05 23.9 0.0 4.0 3 1 1 4 4 4 4 Protein tyrosine kinase RIO1 PF01163.17 EXF79948.1 - 0.17 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Peptidase_S8 PF00082.17 EXF79949.1 - 3.6e-42 144.4 1.9 9.4e-42 143.0 1.4 1.7 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EXF79949.1 - 6.3e-08 33.0 0.0 1.4e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Trypsin PF00089.21 EXF79950.1 - 1.7e-13 50.6 0.1 2.5e-13 50.1 0.1 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.1 EXF79950.1 - 8.8e-08 32.1 0.0 1.5e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain MFS_1 PF07690.11 EXF79951.1 - 3.8e-33 114.6 31.5 6.8e-33 113.8 21.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily FMO-like PF00743.14 EXF79952.1 - 2.1e-15 55.9 0.0 6.7e-15 54.2 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EXF79952.1 - 1e-13 51.8 0.0 2e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF79952.1 - 3.9e-11 42.9 0.2 3.6e-10 39.8 0.0 2.7 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EXF79952.1 - 6.1e-11 42.1 0.0 5.9e-10 39.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EXF79952.1 - 2.5e-08 33.2 0.0 1.8e-06 27.1 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EXF79952.1 - 0.00012 22.0 0.0 0.00066 19.6 0.0 1.8 1 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EXF79952.1 - 0.00013 21.1 0.0 0.00056 19.1 0.0 1.9 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EXF79952.1 - 0.00076 19.8 0.3 1.2 9.5 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF79952.1 - 0.0037 16.3 0.0 0.0077 15.3 0.0 1.5 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EXF79952.1 - 0.0057 15.6 0.1 0.13 11.1 0.0 2.6 2 1 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EXF79952.1 - 0.021 13.8 0.1 0.044 12.8 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EXF79952.1 - 0.023 13.1 0.1 0.035 12.5 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein F-box-like PF12937.2 EXF79953.1 - 0.0022 17.6 0.3 0.0067 16.1 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EXF79953.1 - 0.0039 16.7 0.7 0.013 15.1 0.5 1.9 1 0 0 1 1 1 1 F-box domain 2-Hacid_dh_C PF02826.14 EXF79954.1 - 1.6e-55 186.9 0.0 3.2e-55 186.0 0.0 1.5 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EXF79954.1 - 4.7e-32 110.2 0.0 6e-32 109.9 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EXF79954.1 - 1.8e-08 34.3 0.0 7.2e-08 32.4 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase CoA_binding_2 PF13380.1 EXF79954.1 - 0.00041 20.4 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain IlvN PF07991.7 EXF79954.1 - 0.00084 18.7 0.0 0.0072 15.7 0.0 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain AlaDh_PNT_C PF01262.16 EXF79954.1 - 0.0021 17.6 4.8 0.32 10.5 0.1 2.6 2 1 1 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain GFO_IDH_MocA PF01408.17 EXF79954.1 - 0.0041 17.6 1.4 0.69 10.4 0.0 2.9 2 1 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EXF79954.1 - 0.0068 16.6 0.4 2.2 8.6 0.1 2.5 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Oxidored_nitro PF00148.14 EXF79954.1 - 0.011 14.3 0.0 0.014 14.1 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase AdoHcyase_NAD PF00670.16 EXF79954.1 - 0.017 14.9 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain HisG_C PF08029.6 EXF79954.1 - 0.03 14.2 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 HisG, C-terminal domain 3HCDH_N PF02737.13 EXF79954.1 - 0.063 12.9 0.4 0.39 10.3 0.0 2.3 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 EXF79954.1 - 0.14 12.4 0.0 1.4 9.2 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain CompInhib_SCIN PF11546.3 EXF79954.1 - 0.21 11.4 0.8 12 5.7 0.3 2.9 3 0 0 3 3 3 0 Staphylococcal complement inhibitor SCIN MFS_1 PF07690.11 EXF79955.1 - 2.8e-40 138.1 32.6 2.8e-40 138.1 22.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EXF79955.1 - 2.1e-07 29.5 4.8 3.3e-07 28.9 3.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EXF79955.1 - 8.3e-07 27.9 27.3 2.6e-06 26.2 18.9 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2178 PF09946.4 EXF79955.1 - 0.0018 18.0 2.0 0.0018 18.0 1.4 2.3 2 0 0 2 2 2 1 Predicted membrane protein (DUF2178) DUF221 PF02714.10 EXF79956.1 - 8.6e-83 277.8 23.4 1.3e-82 277.2 16.2 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EXF79956.1 - 7.3e-40 136.0 0.6 4.4e-39 133.5 0.4 2.4 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EXF79956.1 - 3.4e-18 65.9 0.3 6.6e-18 65.0 0.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) DUF904 PF06005.7 EXF79958.1 - 0.0013 18.9 9.8 0.0013 18.9 6.8 4.2 2 1 1 3 3 3 1 Protein of unknown function (DUF904) CCDC155 PF14662.1 EXF79958.1 - 0.005 16.4 21.5 0.005 16.4 14.9 2.4 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 CENP-F_leu_zip PF10473.4 EXF79958.1 - 0.0061 16.4 9.9 0.0061 16.4 6.9 3.4 1 1 2 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ADIP PF11559.3 EXF79958.1 - 0.01 15.7 12.4 0.01 15.7 8.6 3.7 1 1 2 4 4 3 0 Afadin- and alpha -actinin-Binding DUF1515 PF07439.6 EXF79958.1 - 0.022 14.5 1.0 0.022 14.5 0.7 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) IncA PF04156.9 EXF79958.1 - 0.45 10.0 46.5 0.53 9.8 17.0 2.3 1 1 1 2 2 2 0 IncA protein Bacillus_HBL PF05791.6 EXF79958.1 - 0.69 9.2 22.1 0.61 9.4 3.2 3.0 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) Reo_sigmaC PF04582.7 EXF79958.1 - 1.1 8.4 3.8 1.5 7.9 0.6 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Fib_alpha PF08702.5 EXF79958.1 - 1.2 9.2 21.7 0.022 14.8 7.4 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family EMP24_GP25L PF01105.19 EXF79958.1 - 1.2 8.7 11.2 2.3 7.9 5.7 2.8 2 1 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF972 PF06156.8 EXF79958.1 - 2 8.7 27.5 2.9 8.2 8.6 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) K_trans PF02705.11 EXF79959.1 - 6.4e-182 605.6 18.4 7.5e-182 605.4 12.7 1.0 1 0 0 1 1 1 1 K+ potassium transporter Aminotran_4 PF01063.14 EXF79960.1 - 2.2e-20 73.1 0.0 2.9e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Zn_clus PF00172.13 EXF79961.1 - 1.6e-09 37.4 9.2 3.2e-09 36.5 6.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF79961.1 - 0.027 13.3 0.3 0.067 12.0 0.2 1.7 1 0 0 1 1 1 0 Fungal specific transcription factor domain Ring_hydroxyl_A PF00848.14 EXF79962.1 - 1e-25 90.6 5.5 2.5e-24 86.1 3.8 2.2 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 EXF79962.1 - 2e-12 46.4 0.1 3.9e-12 45.5 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Pyr_redox_3 PF13738.1 EXF79963.1 - 1.9e-27 96.6 0.0 1.4e-26 93.8 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EXF79963.1 - 3.2e-19 68.5 0.0 7.6e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EXF79963.1 - 1.4e-13 50.6 0.0 6.8e-13 48.4 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EXF79963.1 - 3.2e-11 42.7 0.1 2.7e-06 26.5 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EXF79963.1 - 3.7e-07 30.0 0.0 4.7e-06 26.4 0.0 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EXF79963.1 - 6.8e-05 21.9 0.1 0.0061 15.5 0.0 2.5 1 1 1 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF79963.1 - 0.00031 20.6 0.0 0.0062 16.4 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF79963.1 - 0.0031 16.6 0.0 0.0096 15.0 0.0 1.8 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EXF79963.1 - 0.0049 17.2 0.0 0.11 12.9 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF79963.1 - 0.05 12.5 0.0 0.4 9.5 0.0 2.4 1 1 0 1 1 1 0 Lycopene cyclase protein Rossmann-like PF10727.4 EXF79963.1 - 0.055 13.1 0.0 0.62 9.7 0.0 2.2 2 0 0 2 2 2 0 Rossmann-like domain Shikimate_DH PF01488.15 EXF79963.1 - 0.076 13.1 0.0 8.5 6.4 0.0 2.5 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase Glyco_transf_20 PF00982.16 EXF79964.1 - 1.1e-164 548.3 0.0 1.6e-164 547.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EXF79964.1 - 2.2e-45 154.3 0.0 6.5e-45 152.8 0.0 1.8 2 0 0 2 2 2 1 Trehalose-phosphatase DUF718 PF05336.8 EXF79964.1 - 0.071 12.9 0.5 5.8 6.7 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF718) Glyco_transf_5 PF08323.6 EXF79964.1 - 0.072 12.5 0.4 0.14 11.5 0.2 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain WD40 PF00400.27 EXF79965.1 - 9.8e-82 266.2 24.0 2e-15 55.9 0.3 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 EXF79965.1 - 6.9e-07 29.1 0.3 0.0017 18.1 0.0 3.5 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EXF79965.1 - 7.5e-06 24.3 3.3 0.043 11.9 0.0 3.9 3 2 0 4 4 4 2 Nucleoporin Nup120/160 NLE PF08154.7 EXF79965.1 - 0.0043 17.0 0.0 0.0083 16.1 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain FAD_binding_9 PF08021.6 EXF79965.1 - 0.022 14.6 0.1 1.1 9.2 0.0 2.9 2 1 1 3 3 3 0 Siderophore-interacting FAD-binding domain DinB PF05163.7 EXF79965.1 - 0.041 13.5 0.1 0.073 12.7 0.1 1.3 1 0 0 1 1 1 0 DinB family PD40 PF07676.7 EXF79965.1 - 0.062 12.9 0.0 12 5.6 0.0 2.9 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Daxx PF03344.10 EXF79966.1 - 4.2 5.7 37.3 0.068 11.6 20.9 1.5 2 0 0 2 2 2 0 Daxx Family MIP-T3 PF10243.4 EXF79966.1 - 9.8 4.5 45.8 3.2 6.1 29.8 1.5 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 MutS_V PF00488.16 EXF79967.1 - 2.2e-71 240.0 0.2 3.4e-71 239.3 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EXF79967.1 - 2.4e-30 105.8 0.5 2.4e-30 105.8 0.4 1.6 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 EXF79967.1 - 7.1e-06 26.1 0.3 2.3e-05 24.4 0.0 2.0 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 EXF79967.1 - 0.00013 22.0 0.0 0.00042 20.3 0.0 1.9 1 0 0 1 1 1 1 MutS domain II Sec63 PF02889.11 EXF79967.1 - 0.0011 18.2 0.6 0.0032 16.7 0.0 2.0 3 0 0 3 3 3 1 Sec63 Brl domain YkuI_C PF10388.4 EXF79967.1 - 0.019 14.6 0.9 0.055 13.1 0.6 1.7 1 0 0 1 1 1 0 EAL-domain associated signalling protein domain GFO_IDH_MocA PF01408.17 EXF79969.1 - 1.1e-25 90.4 0.5 5.8e-25 88.1 0.2 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EXF79969.1 - 2.7e-06 27.1 0.0 6.1e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_2 PF03446.10 EXF79969.1 - 0.0045 16.8 0.1 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Semialdhyde_dh PF01118.19 EXF79969.1 - 0.082 13.2 0.1 0.47 10.7 0.1 2.2 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain DSRB PF10781.4 EXF79969.1 - 0.14 11.7 0.0 0.46 10.0 0.0 1.9 1 0 0 1 1 1 0 Dextransucrase DSRB Fungal_trans_2 PF11951.3 EXF79970.1 - 1.8e-10 39.9 0.8 1.8e-10 39.9 0.5 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF79970.1 - 0.017 14.9 4.5 0.039 13.8 3.1 1.6 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EXF79970.1 - 1.4 9.1 5.2 8.9 6.5 0.6 2.7 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region Sugar_tr PF00083.19 EXF79971.1 - 4e-120 401.4 23.6 5.9e-120 400.8 16.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF79971.1 - 7.7e-30 103.7 50.4 9.6e-25 87.0 20.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 EXF79971.1 - 0.0034 16.1 0.3 0.0034 16.1 0.2 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF791) ALMT PF11744.3 EXF79971.1 - 0.084 11.5 0.7 0.18 10.4 0.5 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter Fungal_trans PF04082.13 EXF79972.1 - 6.4e-20 71.1 0.0 9.8e-20 70.5 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 EXF79973.1 - 2.5e-107 359.2 22.1 2.9e-107 359.0 15.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF79973.1 - 2.2e-22 79.2 25.4 3.1e-15 55.7 1.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EXF79973.1 - 0.00011 20.8 6.9 0.00011 20.8 4.8 3.6 3 1 1 4 4 4 2 MFS/sugar transport protein Dynamin_N PF00350.18 EXF79974.1 - 2.5e-18 66.4 0.1 9.1e-18 64.6 0.0 2.1 2 1 0 2 2 2 1 Dynamin family Dynamin_M PF01031.15 EXF79974.1 - 1.6e-15 56.6 0.3 5.6e-11 41.7 0.0 2.9 3 0 0 3 3 3 2 Dynamin central region MMR_HSR1 PF01926.18 EXF79974.1 - 2.9e-05 23.9 0.0 0.00014 21.7 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.1 EXF79974.1 - 0.00049 20.0 1.9 0.0011 18.9 0.0 2.5 3 0 0 3 3 3 1 AAA domain FeoB_N PF02421.13 EXF79974.1 - 0.0074 15.5 0.1 0.81 8.9 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 EXF79974.1 - 0.0076 16.7 0.0 0.035 14.5 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein DUF3549 PF12069.3 EXF79974.1 - 0.0099 14.6 1.4 0.016 14.0 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3549) Sugar_tr PF00083.19 EXF79975.1 - 3.5e-87 292.8 26.7 4.1e-87 292.6 18.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF79975.1 - 4.6e-19 68.3 23.8 4.6e-19 68.3 16.5 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 EXF79975.1 - 0.024 14.6 2.3 0.14 12.1 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1228) Fungal_trans PF04082.13 EXF79976.1 - 6e-11 41.7 1.7 9.2e-11 41.1 1.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.16 EXF79977.1 - 8.5e-83 277.7 0.0 1.3e-82 277.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF79977.1 - 1.2e-56 191.7 0.0 4.7e-56 189.8 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF79977.1 - 3.6e-20 71.6 0.0 9.6e-20 70.3 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EXF79977.1 - 5.7e-14 51.9 0.1 1.6e-13 50.5 0.1 1.7 1 0 0 1 1 1 1 PA14 domain Cren7 PF11520.3 EXF79977.1 - 0.042 13.4 0.0 0.21 11.2 0.0 2.1 2 0 0 2 2 2 0 Chromatin protein Cren7 adh_short PF00106.20 EXF79978.1 - 4.6e-28 98.2 0.5 6.5e-28 97.7 0.3 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF79978.1 - 9.7e-24 84.4 0.4 1.2e-23 84.1 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF79978.1 - 4.4e-11 42.7 0.1 6.4e-11 42.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF79978.1 - 0.00026 20.5 0.8 0.00091 18.7 0.6 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family MOSC PF03473.12 EXF79979.1 - 7.5e-13 48.1 0.0 1.3e-12 47.3 0.0 1.3 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EXF79979.1 - 7.2e-11 41.8 0.0 1.8e-06 27.6 0.0 2.5 2 1 0 2 2 2 2 MOSC N-terminal beta barrel domain Fungal_trans_2 PF11951.3 EXF79980.1 - 3.7e-30 104.7 1.4 5e-30 104.3 1.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF79980.1 - 5e-10 39.1 11.7 5e-10 39.1 8.1 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldedh PF00171.17 EXF79981.1 - 3.1e-186 619.2 0.2 3.5e-186 619.0 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family KdpC PF02669.10 EXF79981.1 - 0.086 12.5 0.4 0.18 11.4 0.3 1.4 1 0 0 1 1 1 0 K+-transporting ATPase, c chain Ribonuc_L-PSP PF01042.16 EXF79982.1 - 4.2e-21 74.9 0.0 4.9e-21 74.7 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP MFS_1 PF07690.11 EXF79983.1 - 8.1e-30 103.7 23.1 8.1e-30 103.7 16.0 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily SID-1_RNA_chan PF13965.1 EXF79983.1 - 0.073 11.2 0.9 0.12 10.5 0.6 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3464 PF11947.3 EXF79983.1 - 0.35 10.3 1.3 1.2 8.5 0.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) ADH_N PF08240.7 EXF79984.1 - 2.3e-30 104.5 2.9 3.7e-30 103.8 2.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF79984.1 - 8.6e-29 99.7 1.1 1.4e-28 99.0 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF79984.1 - 2e-05 25.4 0.1 3.3e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_assoc PF13823.1 EXF79984.1 - 0.0023 17.5 0.0 0.0038 16.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated ThiF PF00899.16 EXF79984.1 - 0.023 14.5 0.1 0.041 13.7 0.1 1.3 1 0 0 1 1 1 0 ThiF family Methyltransf_26 PF13659.1 EXF79984.1 - 0.028 14.4 0.0 0.53 10.3 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EXF79984.1 - 0.034 14.7 0.0 0.12 13.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain NAS PF03059.11 EXF79984.1 - 0.054 12.6 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Nicotianamine synthase protein AlaDh_PNT_C PF01262.16 EXF79984.1 - 0.058 12.9 0.2 0.058 12.9 0.1 1.7 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.9 EXF79984.1 - 0.069 13.0 0.3 0.13 12.0 0.2 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_11 PF08241.7 EXF79984.1 - 0.081 13.4 0.0 0.19 12.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain F420_oxidored PF03807.12 EXF79984.1 - 0.089 13.2 0.1 0.43 11.0 0.1 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent SET PF00856.23 EXF79985.1 - 6.7e-16 59.0 1.6 3.4e-15 56.7 0.0 2.8 2 2 0 2 2 2 1 SET domain TPR_11 PF13414.1 EXF79985.1 - 2.6e-09 36.5 3.9 0.00026 20.5 0.1 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EXF79985.1 - 1.3e-08 34.0 5.1 3.3e-07 29.7 0.8 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EXF79985.1 - 9.3e-07 28.2 5.4 0.00021 20.7 0.4 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EXF79985.1 - 1.1e-05 25.2 2.8 5.4e-05 23.0 2.2 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EXF79985.1 - 0.004 16.8 1.0 0.02 14.6 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EXF79985.1 - 0.014 15.9 3.0 0.022 15.3 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat SAF PF08666.7 EXF79985.1 - 0.037 14.4 0.0 5 7.5 0.0 2.8 3 0 0 3 3 2 0 SAF domain DMAP1 PF05499.7 EXF79985.1 - 0.038 13.5 0.1 0.038 13.5 0.1 2.4 3 0 0 3 3 3 0 DNA methyltransferase 1-associated protein 1 (DMAP1) TPR_6 PF13174.1 EXF79985.1 - 0.078 13.4 0.2 0.41 11.2 0.1 2.3 1 0 0 1 1 1 0 Tetratricopeptide repeat PapD_N PF00345.15 EXF79985.1 - 0.087 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Pili and flagellar-assembly chaperone, PapD N-terminal domain TPR_16 PF13432.1 EXF79985.1 - 3.5 8.4 7.8 3.6 8.3 0.4 2.4 1 1 2 3 3 3 0 Tetratricopeptide repeat Cyclase PF04199.8 EXF79987.1 - 4.2e-16 59.1 0.2 5.6e-16 58.7 0.1 1.2 1 0 0 1 1 1 1 Putative cyclase Pyr_redox_3 PF13738.1 EXF79988.1 - 4.5e-22 79.1 0.0 1.1e-21 77.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF79988.1 - 1.4e-05 25.0 0.2 5.9e-05 23.0 0.0 2.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EXF79988.1 - 0.00034 20.3 0.0 0.024 14.3 0.0 2.9 3 0 0 3 3 3 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 EXF79988.1 - 0.005 15.9 0.0 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.9 EXF79988.1 - 0.0051 16.7 0.0 13 5.6 0.1 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EXF79988.1 - 0.0064 16.6 0.0 0.021 14.9 0.0 1.9 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EXF79988.1 - 0.041 14.3 0.1 17 5.9 0.0 2.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent GARS_A PF01071.14 EXF79988.1 - 0.054 13.0 0.0 0.23 10.9 0.0 1.9 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain DUF4084 PF13321.1 EXF79988.1 - 0.39 9.8 0.0 0.61 9.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4084) GMC_oxred_N PF00732.14 EXF79989.1 - 2.9e-17 62.7 0.6 2.5e-16 59.7 0.4 2.3 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF79989.1 - 2.5e-16 60.2 0.3 4.2e-16 59.5 0.2 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EXF79989.1 - 6.7e-07 28.5 0.9 3.7e-06 26.0 0.6 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF79989.1 - 1.1e-06 27.8 0.0 0.0023 16.8 0.0 2.4 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EXF79989.1 - 4.5e-06 26.6 0.0 2.7e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF79989.1 - 6.9e-05 22.7 0.2 0.00028 20.8 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EXF79989.1 - 0.00019 20.6 0.0 0.038 13.0 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EXF79989.1 - 0.00041 20.7 0.0 0.13 12.7 0.0 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF79989.1 - 0.0009 19.3 0.1 0.011 15.7 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EXF79989.1 - 0.0021 17.1 0.0 0.0063 15.6 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EXF79989.1 - 0.0052 15.2 0.0 0.01 14.3 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EXF79989.1 - 0.011 14.7 0.0 0.036 13.1 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Lycopene_cycl PF05834.7 EXF79989.1 - 0.15 10.9 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein ABC_tran PF00005.22 EXF79990.1 - 1.9e-47 160.9 0.0 2.5e-25 89.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EXF79990.1 - 7.4e-37 127.2 21.2 1.9e-26 93.0 7.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EXF79990.1 - 1.6e-14 54.5 1.1 0.00023 21.2 0.0 4.3 3 1 1 4 4 4 3 AAA domain SMC_N PF02463.14 EXF79990.1 - 7.5e-12 44.9 2.4 0.00028 20.2 0.0 4.2 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EXF79990.1 - 1.7e-08 34.6 2.7 0.0024 17.9 0.0 3.9 2 1 0 2 2 2 2 AAA domain T2SE PF00437.15 EXF79990.1 - 2.3e-08 33.3 0.8 0.0013 17.6 0.1 2.6 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_29 PF13555.1 EXF79990.1 - 9.4e-08 31.4 0.9 0.0081 15.6 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EXF79990.1 - 1.7e-07 31.4 2.9 0.0008 19.4 0.0 3.1 4 0 0 4 4 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EXF79990.1 - 2e-06 27.4 0.1 0.08 12.4 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_25 PF13481.1 EXF79990.1 - 1.3e-05 24.6 3.9 0.066 12.6 0.0 3.6 3 1 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EXF79990.1 - 5.6e-05 22.9 0.4 0.0044 16.9 0.0 2.8 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EXF79990.1 - 0.00011 22.5 0.6 0.086 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_23 PF13476.1 EXF79990.1 - 0.00015 22.1 0.8 0.18 12.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EXF79990.1 - 0.00019 22.2 1.9 0.11 13.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EXF79990.1 - 0.00038 20.3 0.0 0.28 11.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EXF79990.1 - 0.0005 19.8 0.1 0.052 13.2 0.0 3.1 3 0 0 3 3 3 1 Archaeal ATPase DUF258 PF03193.11 EXF79990.1 - 0.0013 17.9 0.2 0.66 9.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_10 PF12846.2 EXF79990.1 - 0.0019 17.7 4.2 0.3 10.4 0.0 3.5 4 0 0 4 4 4 1 AAA-like domain MMR_HSR1 PF01926.18 EXF79990.1 - 0.002 18.0 0.2 2.9 7.8 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase UPF0079 PF02367.12 EXF79990.1 - 0.0034 17.0 1.4 0.078 12.6 0.1 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 EXF79990.1 - 0.0054 17.2 0.6 6.1 7.3 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein MobB PF03205.9 EXF79990.1 - 0.011 15.4 2.8 1.6 8.4 0.3 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DEAD PF00270.24 EXF79990.1 - 0.015 14.7 0.5 6.3 6.2 0.0 3.0 3 0 0 3 3 3 0 DEAD/DEAH box helicase NB-ARC PF00931.17 EXF79990.1 - 0.02 13.7 0.1 4.1 6.1 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain Pox_A32 PF04665.7 EXF79990.1 - 0.026 13.8 1.0 4 6.6 0.0 2.7 3 0 0 3 3 2 0 Poxvirus A32 protein DUF87 PF01935.12 EXF79990.1 - 0.03 14.1 0.1 0.03 14.1 0.1 2.6 3 0 0 3 3 2 0 Domain of unknown function DUF87 NACHT PF05729.7 EXF79990.1 - 0.036 13.7 7.2 0.37 10.4 0.1 3.8 4 0 0 4 4 3 0 NACHT domain IstB_IS21 PF01695.12 EXF79990.1 - 0.1 11.9 1.9 4.3 6.7 0.0 3.1 3 0 0 3 3 2 0 IstB-like ATP binding protein cobW PF02492.14 EXF79990.1 - 0.11 11.8 5.2 0.24 10.8 1.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.22 EXF79990.1 - 0.12 11.8 0.4 13 5.2 0.1 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EXF79990.1 - 0.2 11.1 4.1 1.2 8.5 0.3 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 EXF79990.1 - 0.24 10.9 1.8 25 4.3 0.1 3.3 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 EXF79990.1 - 0.28 11.0 0.7 6.9 6.4 0.0 2.5 2 0 0 2 2 2 0 Dynamin family AAA_19 PF13245.1 EXF79990.1 - 0.47 10.2 5.2 0.89 9.3 0.4 3.0 3 0 0 3 3 2 0 Part of AAA domain NTPase_1 PF03266.10 EXF79990.1 - 2.7 7.6 11.2 4.4 6.9 0.0 3.9 4 0 0 4 4 4 0 NTPase AAA PF00004.24 EXF79990.1 - 4 7.6 6.2 24 5.1 0.2 3.5 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) FAD_binding_4 PF01565.18 EXF79992.1 - 2.8e-23 81.9 1.9 4.4e-23 81.2 1.3 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF79992.1 - 0.0013 18.5 0.0 0.003 17.4 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like RRM_1 PF00076.17 EXF79995.1 - 2.2e-46 155.3 0.0 1.7e-16 59.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF79995.1 - 1.9e-25 88.5 0.0 6.7e-10 38.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF79995.1 - 2.1e-20 72.3 0.0 1.4e-08 34.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EXF79995.1 - 1.7e-05 24.6 0.0 0.00016 21.4 0.0 2.3 3 0 0 3 3 3 1 RNA binding motif Nup35_RRM_2 PF14605.1 EXF79995.1 - 0.00022 20.9 0.1 0.0037 17.0 0.0 2.6 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif Ecm29 PF13001.2 EXF79996.1 - 1.7e-89 300.6 0.0 2.8e-89 299.9 0.0 1.4 1 0 0 1 1 1 1 Proteasome stabiliser HEAT PF02985.17 EXF79996.1 - 3.6e-07 29.7 1.1 2.2 8.5 0.0 7.6 8 0 0 8 8 8 2 HEAT repeat UBA_4 PF14555.1 EXF79997.1 - 1e-15 56.9 0.5 2.2e-15 55.8 0.4 1.6 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.1 EXF79997.1 - 2.8e-14 52.8 0.1 5.4e-14 51.9 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.15 EXF79997.1 - 6e-07 29.4 0.0 1.1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 UBX domain Thioredox_DsbH PF03190.10 EXF79997.1 - 0.0042 16.8 0.0 0.007 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Pkinase PF00069.20 EXF79998.1 - 1.3e-69 234.2 0.0 2.5e-69 233.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF79998.1 - 1.6e-50 171.6 0.0 2.7e-50 170.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF79998.1 - 0.0037 16.2 0.0 0.0076 15.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PAT1 PF09770.4 EXF79998.1 - 9.7 4.2 20.6 15 3.6 14.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1602 PF07673.9 EXF79999.1 - 0.9 9.0 6.5 2 7.9 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1602) Cullin_binding PF03556.10 EXF80000.1 - 0.0094 16.0 0.5 0.014 15.5 0.4 1.2 1 0 0 1 1 1 1 Cullin binding DUF3016 PF11454.3 EXF80000.1 - 0.12 12.0 0.2 0.17 11.4 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3016) End3 PF12761.2 EXF80000.1 - 0.26 10.9 3.2 0.22 11.1 1.4 1.4 1 1 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 Pox_A_type_inc PF04508.7 EXF80000.1 - 0.26 11.1 2.1 0.66 9.9 1.5 1.7 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat Asp_protease_2 PF13650.1 EXF80001.1 - 7.9e-05 23.0 0.0 0.00019 21.8 0.0 1.6 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.15 EXF80001.1 - 0.0017 18.2 0.0 0.0036 17.1 0.0 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease BAR_3_WASP_bdg PF10456.4 EXF80001.1 - 0.1 11.8 0.0 0.26 10.4 0.0 1.6 1 1 0 1 1 1 0 WASP-binding domain of Sorting nexin protein MFS_1 PF07690.11 EXF80003.1 - 1.4e-12 47.0 18.3 2.2e-12 46.3 12.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF80003.1 - 0.00014 20.5 5.7 0.00024 19.8 4.0 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter UNC-93 PF05978.11 EXF80003.1 - 0.00016 21.2 0.7 0.00036 20.0 0.5 1.6 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 FMO-like PF00743.14 EXF80004.1 - 3.1e-25 88.3 0.0 4.1e-11 41.7 0.1 3.1 2 1 1 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EXF80004.1 - 1.1e-20 74.5 0.0 3.7e-19 69.6 0.0 2.7 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF80004.1 - 9.3e-10 37.9 0.0 3.5e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EXF80004.1 - 9.2e-09 35.2 0.0 2.1e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EXF80004.1 - 3.8e-07 30.1 0.0 0.00068 19.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF80004.1 - 2.7e-05 24.0 0.0 7.5e-05 22.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF80004.1 - 0.021 13.7 0.0 1.9 7.2 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 EXF80004.1 - 0.059 12.4 0.3 0.12 11.4 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Pyr_redox PF00070.22 EXF80004.1 - 0.24 11.8 1.5 4.1 7.8 0.0 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Hemerythrin PF01814.18 EXF80005.1 - 0.044 13.9 0.0 0.053 13.6 0.0 1.1 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain Sugar_tr PF00083.19 EXF80007.1 - 7.5e-85 285.1 24.9 8.8e-85 284.9 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF80007.1 - 2e-17 62.9 29.5 5.8e-15 54.8 15.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EXF80007.1 - 0.0049 15.3 34.0 0.028 12.8 6.7 3.9 2 2 2 4 4 4 3 MFS/sugar transport protein Sterol_MT_C PF08498.5 EXF80008.1 - 1.9e-25 88.5 0.3 3.3e-25 87.8 0.2 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EXF80008.1 - 7e-23 80.9 0.0 1.4e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF80008.1 - 1.8e-20 73.0 0.0 2.6e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF80008.1 - 1.7e-17 63.6 0.0 3.6e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF80008.1 - 1.2e-15 57.7 0.0 2.5e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF80008.1 - 8.9e-14 51.1 0.0 1.5e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EXF80008.1 - 8e-12 44.8 0.1 1.2e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_18 PF12847.2 EXF80008.1 - 1.1e-11 45.3 0.0 2.3e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF80008.1 - 1.1e-11 45.0 0.1 3.1e-11 43.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF80008.1 - 3.5e-10 39.9 0.0 1e-09 38.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF80008.1 - 4.4e-06 26.1 0.0 7.1e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EXF80008.1 - 3.1e-05 23.6 0.0 5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EXF80008.1 - 5.1e-05 22.5 0.1 0.00025 20.2 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 EXF80008.1 - 0.00021 20.8 0.0 0.00031 20.3 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_8 PF05148.10 EXF80008.1 - 0.00092 18.9 0.0 0.0026 17.4 0.0 1.8 1 1 0 1 1 1 1 Hypothetical methyltransferase RrnaAD PF00398.15 EXF80008.1 - 0.0013 17.7 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.1 EXF80008.1 - 0.0021 17.7 0.0 0.0044 16.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EXF80008.1 - 0.0064 15.8 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_2 PF00891.13 EXF80008.1 - 0.0082 15.3 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase UPF0020 PF01170.13 EXF80008.1 - 0.013 15.1 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Pox_MCEL PF03291.11 EXF80008.1 - 0.023 13.5 0.6 0.18 10.6 0.0 2.0 2 0 0 2 2 2 0 mRNA capping enzyme Methyltransf_29 PF03141.11 EXF80008.1 - 0.029 12.7 0.0 0.045 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Pec_lyase_C PF00544.14 EXF80009.1 - 2.2e-27 95.8 7.1 5.7e-25 87.9 4.9 2.3 1 1 0 1 1 1 1 Pectate lyase Beta_helix PF13229.1 EXF80009.1 - 7.1e-06 25.8 2.3 1.3e-05 24.9 1.6 1.5 1 1 0 1 1 1 1 Right handed beta helix region COesterase PF00135.23 EXF80010.1 - 4.6e-93 312.7 0.0 5.6e-93 312.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF80010.1 - 9e-05 22.1 0.0 0.00022 20.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Aldo_ket_red PF00248.16 EXF80011.1 - 4.4e-67 225.8 0.0 5.8e-67 225.4 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family EGF_2 PF07974.8 EXF80012.1 - 4.1 7.6 12.5 8.9 6.5 1.9 2.7 2 0 0 2 2 2 0 EGF-like domain Methyltransf_11 PF08241.7 EXF80014.1 - 7.4e-21 74.4 0.0 1.6e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF80014.1 - 2e-17 63.1 0.0 3e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF80014.1 - 2.4e-14 53.3 0.0 3.6e-14 52.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF80014.1 - 1.4e-11 44.6 0.0 2.4e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EXF80014.1 - 4.1e-11 42.4 0.0 5.5e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.7 EXF80014.1 - 7.5e-11 42.3 0.0 1.5e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF80014.1 - 1.5e-10 40.6 0.0 5e-10 38.8 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EXF80014.1 - 1.2e-08 35.0 0.1 3.4e-08 33.5 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF80014.1 - 1.2e-08 35.4 0.0 2.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EXF80014.1 - 2e-05 24.0 0.0 3.4e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.9 EXF80014.1 - 2.6e-05 23.6 0.0 4.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain TehB PF03848.9 EXF80014.1 - 0.00039 19.6 0.0 0.00065 18.9 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB PrmA PF06325.8 EXF80014.1 - 0.00051 19.2 0.0 0.00079 18.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) FmrO PF07091.6 EXF80014.1 - 0.00059 18.8 0.0 0.002 17.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal RNA methyltransferase (FmrO) PCMT PF01135.14 EXF80014.1 - 0.0009 18.8 0.0 0.0015 18.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 EXF80014.1 - 0.0076 15.3 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.12 EXF80014.1 - 0.0082 15.2 0.0 0.027 13.5 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase UPF0020 PF01170.13 EXF80014.1 - 0.044 13.3 0.0 0.13 11.8 0.0 1.7 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Methyltransf_32 PF13679.1 EXF80014.1 - 0.046 13.4 0.0 0.084 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.8 EXF80014.1 - 0.062 12.5 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 DREV PF05219.7 EXF80014.1 - 0.094 11.5 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_2 PF00891.13 EXF80014.1 - 0.13 11.4 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Iso_dh PF00180.15 EXF80016.1 - 2.8e-82 276.4 0.1 3.2e-82 276.2 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase p450 PF00067.17 EXF80017.1 - 4e-60 203.6 0.0 5.1e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 NAAA-beta PF15508.1 EXF80018.1 - 2.3e-20 72.7 0.0 3.8e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Toxin_22 PF08092.6 EXF80019.1 - 0.17 11.7 2.6 11 5.9 0.0 2.4 2 0 0 2 2 2 0 Magi peptide toxin family Acetyltransf_1 PF00583.19 EXF80020.1 - 0.028 14.4 0.0 0.063 13.3 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) family ADH_zinc_N PF00107.21 EXF80021.1 - 2.3e-20 72.4 0.0 3.5e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF80021.1 - 6.3e-10 40.0 0.0 1.5e-09 38.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Dynamin_N PF00350.18 EXF80022.1 - 1e-29 103.4 0.0 2.5e-29 102.2 0.0 1.7 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EXF80022.1 - 3.3e-10 39.2 0.0 8.3e-10 37.9 0.0 1.6 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 EXF80022.1 - 4.6e-05 23.3 0.0 0.00019 21.3 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EXF80022.1 - 0.0063 17.0 0.0 0.016 15.6 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein ABC_tran PF00005.22 EXF80022.1 - 0.042 14.1 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 ABC transporter DUF605 PF04652.11 EXF80022.1 - 0.38 10.0 21.1 0.59 9.4 14.7 1.2 1 0 0 1 1 1 0 Vta1 like adh_short PF00106.20 EXF80023.1 - 1e-14 54.8 0.0 1.6e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF80023.1 - 6.4e-05 22.6 0.0 9.7e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Shikimate_DH PF01488.15 EXF80023.1 - 0.019 15.0 0.0 0.055 13.5 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EXF80023.1 - 0.034 13.0 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Erv26 PF04148.8 EXF80025.1 - 4.8e-87 290.7 5.1 6e-87 290.4 3.6 1.1 1 0 0 1 1 1 1 Transmembrane adaptor Erv26 Cytochrom_C_asm PF01578.15 EXF80025.1 - 0.0037 16.8 0.2 0.0037 16.8 0.1 1.6 3 0 0 3 3 3 1 Cytochrome C assembly protein DUF3377 PF11857.3 EXF80025.1 - 0.0082 15.7 1.5 0.025 14.1 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF3377) DUF1970 PF09301.5 EXF80025.1 - 0.15 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1970) Claudin_2 PF13903.1 EXF80025.1 - 0.89 9.2 4.9 3.3 7.3 3.2 2.1 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction WBS_methylT PF12589.3 EXF80026.1 - 3.2e-17 62.7 7.6 6.1e-17 61.8 5.3 1.5 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EXF80026.1 - 1.4e-11 44.6 0.0 3.3e-11 43.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF80026.1 - 3.6e-08 33.6 0.0 7.8e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF80026.1 - 1.5e-05 25.3 0.0 6e-05 23.4 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF80026.1 - 1.6e-05 24.9 0.0 2.9e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF80026.1 - 2.5e-05 23.9 0.0 3.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF80026.1 - 8.6e-05 22.3 0.0 0.00012 21.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF80026.1 - 0.00025 21.5 0.0 0.00064 20.2 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EXF80026.1 - 0.00071 19.1 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EXF80026.1 - 0.0019 17.3 0.0 0.043 12.8 0.0 2.1 2 0 0 2 2 2 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EXF80026.1 - 0.03 13.4 0.0 0.092 11.8 0.0 1.8 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family p450 PF00067.17 EXF80027.1 - 4.8e-69 233.0 0.0 6.1e-69 232.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Inhibitor_I9 PF05922.11 EXF80028.1 - 0.00055 20.4 0.0 0.0012 19.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor I9 HET PF06985.6 EXF80029.1 - 1e-36 126.1 0.5 1.8e-36 125.3 0.3 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ADC PF06314.6 EXF80030.1 - 0.00022 20.6 0.0 0.00034 20.0 0.0 1.3 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) HET PF06985.6 EXF80031.1 - 3.2e-26 92.1 1.3 5.1e-26 91.4 0.2 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Abhydrolase_6 PF12697.2 EXF80032.1 - 7.9e-25 88.0 0.0 9.1e-25 87.8 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF80032.1 - 3.8e-10 39.6 0.0 5e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF80032.1 - 0.00081 19.0 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.7 EXF80032.1 - 0.0087 15.4 0.0 0.021 14.1 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF900) AA_kinase PF00696.23 EXF80032.1 - 0.021 14.3 0.0 0.026 14.0 0.0 1.2 1 0 0 1 1 1 0 Amino acid kinase family DUF362 PF04015.7 EXF80032.1 - 0.041 13.3 0.0 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF362) PGAP1 PF07819.8 EXF80032.1 - 0.043 13.4 0.0 0.067 12.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein PE-PPE PF08237.6 EXF80032.1 - 0.078 12.3 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 PE-PPE domain Abhydrolase_8 PF06259.7 EXF80032.1 - 0.11 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase BCS1_N PF08740.6 EXF80033.1 - 3.1e-31 108.4 1.6 3.4e-31 108.3 0.0 1.7 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 EXF80033.1 - 6.5e-14 52.2 0.0 4.1e-13 49.6 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EXF80033.1 - 8.8e-06 24.9 0.0 1.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EXF80033.1 - 0.00017 22.3 0.1 0.0017 19.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EXF80033.1 - 0.0033 17.0 0.1 0.0087 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EXF80033.1 - 0.0072 15.7 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EXF80033.1 - 0.012 15.6 0.2 0.07 13.1 0.0 2.2 1 1 1 2 2 2 0 AAA ATPase domain AAA_19 PF13245.1 EXF80033.1 - 0.021 14.5 0.0 0.06 13.1 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_5 PF07728.9 EXF80033.1 - 0.03 14.0 0.0 0.1 12.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EXF80033.1 - 0.033 14.3 0.0 0.23 11.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EXF80033.1 - 0.037 13.4 0.0 0.076 12.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein HNH_3 PF13392.1 EXF80033.1 - 0.038 13.3 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 HNH endonuclease KaiC PF06745.8 EXF80033.1 - 0.048 12.7 0.0 0.098 11.7 0.0 1.4 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.1 EXF80033.1 - 0.059 12.9 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EXF80033.1 - 0.15 11.9 2.2 0.36 10.7 0.0 2.4 3 0 0 3 3 3 0 AAA domain Glyco_hydro_76 PF03663.9 EXF80034.1 - 7.5e-118 394.1 9.0 9.6e-118 393.7 6.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Herpes_capsid PF06112.6 EXF80034.1 - 8 6.4 8.7 16 5.5 6.1 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Fungal_trans_2 PF11951.3 EXF80036.1 - 2.1e-06 26.6 0.0 2.8e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF80036.1 - 0.00025 20.8 1.2 0.00044 20.0 0.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EXF80038.1 - 1.6e-29 102.7 31.0 1.8e-29 102.5 19.2 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily DivIC PF04977.10 EXF80038.1 - 0.089 12.2 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 Septum formation initiator Fungal_trans_2 PF11951.3 EXF80039.1 - 0.00041 19.0 2.8 0.00074 18.2 2.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DLH PF01738.13 EXF80040.1 - 1.6e-26 92.9 0.0 2.3e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EXF80040.1 - 4e-06 26.6 0.0 5.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF80040.1 - 7.3e-05 22.4 0.0 0.00017 21.2 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase PF07224.6 EXF80040.1 - 0.00095 18.0 0.0 0.0013 17.6 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_6 PF12697.2 EXF80040.1 - 0.0014 18.5 0.0 0.022 14.6 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family MFS_1 PF07690.11 EXF80041.1 - 5.3e-36 124.0 55.0 1.3e-26 93.1 22.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_7 PF00840.15 EXF80042.1 - 5e-189 628.1 13.8 5.8e-189 627.9 9.6 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Gamma-thionin PF00304.15 EXF80042.1 - 0.023 14.7 0.7 0.023 14.7 0.5 2.8 3 0 0 3 3 3 0 Gamma-thionin family DUF3425 PF11905.3 EXF80043.1 - 8.1e-33 113.1 0.0 1.4e-32 112.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) EABR PF12180.3 EXF80043.1 - 0.023 14.0 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 Tannase PF07519.6 EXF80044.1 - 1.4e-77 261.4 0.1 3.6e-77 260.0 0.3 1.5 2 0 0 2 2 2 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EXF80044.1 - 2e-24 86.7 0.0 6.6e-18 65.4 0.0 3.3 3 1 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF80044.1 - 8.6e-14 51.6 0.0 1.8e-09 37.4 0.0 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF80044.1 - 8.1e-11 41.8 0.0 5e-08 32.8 0.0 3.3 3 0 0 3 3 3 1 Alpha/beta hydrolase family Fungal_trans_2 PF11951.3 EXF80044.1 - 1e-07 30.9 0.0 1.6e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Esterase PF00756.15 EXF80044.1 - 9.9e-06 25.1 0.1 0.0092 15.4 0.0 2.4 2 0 0 2 2 2 2 Putative esterase Peptidase_S9 PF00326.16 EXF80044.1 - 9.5e-05 21.7 0.0 0.63 9.2 0.0 3.2 3 0 0 3 3 3 2 Prolyl oligopeptidase family Peptidase_S28 PF05577.7 EXF80044.1 - 0.051 12.1 0.0 0.079 11.5 0.0 1.2 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Abhydrolase_4 PF08386.5 EXF80046.1 - 1.7e-18 66.3 0.0 3.6e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 TAP-like protein ADH_zinc_N PF00107.21 EXF80046.1 - 1.8e-09 37.2 0.1 5.2e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Abhydrolase_1 PF00561.15 EXF80046.1 - 2.2e-07 30.6 0.0 0.00028 20.5 0.0 3.0 3 0 0 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EXF80046.1 - 2e-06 27.8 0.1 5.4e-05 23.1 0.1 2.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family ADH_N PF08240.7 EXF80046.1 - 4.2e-06 26.4 0.3 1.7e-05 24.5 0.0 2.2 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EXF80046.1 - 2.7e-05 25.0 0.0 9.1e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EXF80046.1 - 0.03 14.3 0.0 0.08 12.9 0.0 1.7 1 0 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EXF80046.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MFS_1 PF07690.11 EXF80047.1 - 8.6e-21 74.0 57.3 5.3e-11 41.8 16.3 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily PolyG_pol PF01518.11 EXF80047.1 - 0.074 11.5 0.1 0.12 10.8 0.1 1.3 1 0 0 1 1 1 0 Sigma NS protein OPT PF03169.10 EXF80049.1 - 6.4e-165 550.1 43.3 7.3e-165 549.9 30.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Epimerase PF01370.16 EXF80050.1 - 7.5e-12 45.1 0.1 1.5e-11 44.1 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EXF80050.1 - 4.5e-07 28.8 0.0 8.6e-07 27.9 0.0 1.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EXF80050.1 - 5.2e-07 29.8 0.1 1.5e-06 28.3 0.1 1.7 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EXF80050.1 - 8.6e-07 28.1 0.0 3.8e-05 22.7 0.0 2.3 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EXF80050.1 - 5.8e-05 22.4 0.0 8.2e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EXF80050.1 - 0.00084 19.2 0.0 0.003 17.5 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF80050.1 - 0.16 11.6 0.1 20 4.8 0.0 2.3 2 0 0 2 2 2 0 KR domain Meth_synt_2 PF01717.13 EXF80051.1 - 2.9e-12 46.2 0.0 4e-11 42.4 0.0 2.3 2 1 0 2 2 2 1 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EXF80051.1 - 8.5e-06 25.2 0.1 0.0039 16.4 0.0 3.2 3 1 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain RGS PF00615.14 EXF80052.1 - 8.5e-05 22.6 0.0 0.00046 20.2 0.0 2.0 1 1 0 1 1 1 1 Regulator of G protein signaling domain RCR PF12273.3 EXF80053.1 - 0.076 13.5 1.0 0.17 12.4 0.7 1.6 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red DUF202 PF02656.10 EXF80053.1 - 0.089 13.0 0.3 0.17 12.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF202) ATG27 PF09451.5 EXF80053.1 - 0.1 11.8 0.3 0.14 11.3 0.2 1.2 1 0 0 1 1 1 0 Autophagy-related protein 27 UPF0370 PF13980.1 EXF80053.1 - 0.19 11.5 2.6 0.3 10.9 1.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) Methyltransf_23 PF13489.1 EXF80054.1 - 2.3e-05 24.1 0.0 3.5e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF80054.1 - 4.9e-05 23.6 0.0 9.6e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF80054.1 - 5.8e-05 23.4 0.0 9.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF80054.1 - 0.0009 18.8 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF80054.1 - 0.033 14.7 0.0 0.054 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EXF80054.1 - 0.15 12.5 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain hDGE_amylase PF14701.1 EXF80055.1 - 2e-178 593.6 0.0 2.6e-178 593.2 0.0 1.1 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EXF80055.1 - 4.2e-113 377.8 0.2 8.1e-113 376.8 0.0 1.5 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EXF80055.1 - 1.4e-89 299.7 0.0 4e-89 298.2 0.0 1.8 2 0 0 2 2 2 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EXF80055.1 - 2.5e-27 94.5 0.0 8.2e-27 92.8 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.19 EXF80055.1 - 0.00055 19.4 0.0 0.66 9.3 0.0 2.3 2 0 0 2 2 2 2 Alpha amylase, catalytic domain NAD_Gly3P_dh_N PF01210.18 EXF80056.1 - 1.3e-46 158.2 0.0 5.8e-46 156.0 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_Gly3P_dh_C PF07479.9 EXF80056.1 - 5.1e-41 139.8 0.2 8.3e-41 139.1 0.1 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus AIG2_2 PF13772.1 EXF80057.1 - 3.2e-06 27.1 0.0 2.6e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 AIG2-like family Chromo PF00385.19 EXF80058.1 - 2e-07 30.5 0.1 1.1e-05 25.0 0.0 2.4 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Chorein_N PF12624.2 EXF80058.1 - 0.029 13.9 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 N-terminal region of Chorein, a TM vesicle-mediated sorter ketoacyl-synt PF00109.21 EXF80059.1 - 1.8e-72 243.9 0.0 3.4e-72 242.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EXF80059.1 - 2.6e-50 171.5 0.0 4.4e-50 170.8 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Thioesterase PF00975.15 EXF80059.1 - 5.5e-47 160.9 0.0 1.4e-46 159.6 0.0 1.7 1 0 0 1 1 1 1 Thioesterase domain Ketoacyl-synt_C PF02801.17 EXF80059.1 - 1.1e-35 122.0 0.7 1.1e-35 122.0 0.5 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.20 EXF80059.1 - 1.7e-20 73.0 3.5 9.1e-10 38.6 0.1 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site PS-DH PF14765.1 EXF80059.1 - 9.7e-20 70.8 0.0 2.8e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 Polyketide synthase dehydratase Abhydrolase_5 PF12695.2 EXF80059.1 - 1.2e-05 25.0 0.2 0.18 11.5 0.0 3.3 3 0 0 3 3 3 2 Alpha/beta hydrolase family Thiolase_N PF00108.18 EXF80059.1 - 0.00086 18.3 0.1 0.002 17.1 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ribosomal_60s PF00428.14 EXF80059.1 - 0.31 11.4 14.1 0.83 10.0 5.8 3.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein Cu-oxidase_3 PF07732.10 EXF80060.1 - 5.9e-46 155.0 8.5 2.5e-40 136.8 1.3 4.2 4 0 0 4 4 4 3 Multicopper oxidase Cu-oxidase_2 PF07731.9 EXF80060.1 - 3e-37 127.2 13.2 1.4e-34 118.5 2.0 3.8 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EXF80060.1 - 2.3e-25 89.3 2.7 3.6e-23 82.2 0.0 3.0 3 1 0 3 3 3 2 Multicopper oxidase DUF4033 PF13225.1 EXF80061.1 - 0.01 15.4 1.9 0.012 15.2 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4033) Oxysterol_BP PF01237.13 EXF80062.1 - 1.1e-108 362.8 0.0 4e-108 361.0 0.0 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein PH_8 PF15409.1 EXF80062.1 - 7.2e-39 131.7 1.1 3.8e-38 129.4 0.1 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EXF80062.1 - 2.6e-05 24.3 0.0 9.3e-05 22.5 0.0 2.0 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EXF80062.1 - 0.064 13.5 5.2 0.14 12.3 1.4 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain Ribosomal_L27e PF01777.13 EXF80062.1 - 0.2 11.7 0.7 28 4.9 0.0 2.5 2 0 0 2 2 2 0 Ribosomal L27e protein family ArfGap PF01412.13 EXF80063.1 - 3.9e-39 133.0 0.1 3.9e-39 133.0 0.1 2.0 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf UBA PF00627.26 EXF80063.1 - 0.00052 19.7 0.1 0.0011 18.7 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Foie-gras_1 PF11817.3 EXF80063.1 - 6.1 6.2 11.5 15 4.9 8.0 1.7 1 0 0 1 1 1 0 Foie gras liver health family 1 Pyridoxal_deC PF00282.14 EXF80064.1 - 5.8e-27 94.1 0.0 7.5e-27 93.7 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EXF80064.1 - 1.8e-05 24.0 0.0 2.1e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EXF80064.1 - 0.0012 17.8 0.0 0.0018 17.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF92 PF01940.11 EXF80065.1 - 1.9e-66 223.4 3.0 2.8e-66 222.9 2.1 1.2 1 0 0 1 1 1 1 Integral membrane protein DUF92 Mito_carr PF00153.22 EXF80066.1 - 1.8e-55 184.6 0.4 6.1e-19 67.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_L22e PF01776.12 EXF80067.1 - 3.1e-48 162.4 1.7 3.9e-48 162.1 1.1 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Herpes_gI PF01688.12 EXF80067.1 - 0.16 11.1 0.0 0.19 10.8 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I NmrA PF05368.8 EXF80068.1 - 2e-11 43.6 0.0 7.8e-10 38.3 0.0 2.1 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF80068.1 - 2e-07 31.1 0.6 1.2e-06 28.7 0.4 2.1 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EXF80068.1 - 5.7e-05 22.2 0.0 7.1e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase TrkA_N PF02254.13 EXF80068.1 - 0.00052 19.9 0.1 0.00082 19.3 0.1 1.3 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.1 EXF80068.1 - 0.0016 18.6 0.0 0.0029 17.8 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding TcpQ PF10671.4 EXF80068.1 - 0.0062 16.4 1.8 0.077 12.8 0.7 2.5 3 0 0 3 3 3 1 Toxin co-regulated pilus biosynthesis protein Q Shikimate_DH PF01488.15 EXF80068.1 - 0.011 15.7 0.1 0.019 15.0 0.1 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_Gly3P_dh_N PF01210.18 EXF80068.1 - 0.021 14.5 0.1 0.04 13.6 0.0 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.12 EXF80068.1 - 0.028 14.8 0.1 0.059 13.8 0.1 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 EXF80068.1 - 0.073 11.7 0.0 0.17 10.5 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ApbA PF02558.11 EXF80068.1 - 0.15 11.5 0.1 0.3 10.4 0.0 1.6 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA A_deaminase PF00962.17 EXF80069.1 - 2.4e-40 138.4 0.0 1.3e-39 136.0 0.0 1.9 1 1 0 1 1 1 1 Adenosine/AMP deaminase Formyl_trans_C PF02911.13 EXF80069.1 - 0.092 12.8 0.0 0.23 11.5 0.0 1.7 2 0 0 2 2 2 0 Formyl transferase, C-terminal domain DUF2462 PF09495.5 EXF80070.1 - 1.5e-11 44.8 13.2 1.5e-11 44.8 9.1 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2462) Peptidase_S30 PF01577.11 EXF80070.1 - 0.02 14.2 1.5 0.023 14.0 1.1 1.0 1 0 0 1 1 1 0 Potyvirus P1 protease AMP-binding PF00501.23 EXF80071.1 - 2.4e-80 270.0 0.0 3.8e-80 269.3 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme ketoacyl-synt PF00109.21 EXF80071.1 - 1e-74 251.2 0.0 2.1e-74 250.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EXF80071.1 - 8.4e-64 215.8 0.0 1.4e-63 215.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EXF80071.1 - 2.7e-58 196.5 10.6 2.8e-57 193.2 0.8 4.2 4 0 0 4 4 4 1 KR domain PS-DH PF14765.1 EXF80071.1 - 2.2e-53 181.3 0.0 3.7e-53 180.6 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EXF80071.1 - 2.2e-48 164.3 10.8 3.9e-47 160.2 0.3 4.5 4 0 0 4 4 4 1 short chain dehydrogenase Condensation PF00668.15 EXF80071.1 - 6.9e-43 146.6 0.0 1.1e-42 145.9 0.0 1.3 1 0 0 1 1 1 1 Condensation domain Ketoacyl-synt_C PF02801.17 EXF80071.1 - 3.7e-40 136.4 0.0 5.1e-39 132.7 0.0 2.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 EXF80071.1 - 5e-39 133.7 0.0 1.5e-38 132.2 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein ADH_zinc_N PF00107.21 EXF80071.1 - 1.2e-18 66.8 0.1 3.5e-18 65.3 0.1 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EXF80071.1 - 4.3e-17 62.1 0.1 3e-07 30.5 0.0 3.1 3 0 0 3 3 2 2 Phosphopantetheine attachment site HxxPF_rpt PF13745.1 EXF80071.1 - 4.8e-12 46.0 0.0 1.3e-11 44.6 0.0 1.8 1 0 0 1 1 1 1 HxxPF-repeated domain ADH_zinc_N_2 PF13602.1 EXF80071.1 - 2.4e-09 38.1 0.0 2.5e-08 34.8 0.0 2.9 3 0 0 3 3 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF80071.1 - 3.6e-06 26.7 0.0 7.6e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 3Beta_HSD PF01073.14 EXF80071.1 - 0.00015 20.5 0.0 0.0093 14.6 0.0 2.5 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family eIF2A PF08662.6 EXF80071.1 - 0.069 12.8 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A P2X_receptor PF00864.14 EXF80071.1 - 2 7.0 0.0 3.3 6.3 0.0 1.2 1 0 0 1 1 1 0 ATP P2X receptor TFIIF_alpha PF05793.7 EXF80071.1 - 9 4.5 0.0 17 3.6 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ADH_zinc_N PF00107.21 EXF80076.1 - 2.9e-11 43.0 0.0 5.6e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF80076.1 - 8.3e-08 31.9 1.1 5e-07 29.4 0.6 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain zf-H2C2_2 PF13465.1 EXF80077.1 - 2.1e-14 52.9 8.4 4.8e-08 32.9 0.2 3.8 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EXF80077.1 - 2e-12 46.6 11.1 7.4e-06 26.0 1.6 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF80077.1 - 2.5e-11 43.0 11.2 3.6e-05 23.8 1.8 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EXF80077.1 - 1.8e-07 31.1 1.8 0.028 14.5 0.1 3.6 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EXF80077.1 - 2e-05 24.6 1.2 0.013 15.7 0.2 3.4 3 0 0 3 3 3 1 Zinc-finger of C2H2 type PG_binding_2 PF08823.6 EXF80077.1 - 0.065 13.3 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Putative peptidoglycan binding domain Zn_ribbon_recom PF13408.1 EXF80077.1 - 0.2 11.9 0.5 0.49 10.7 0.4 1.6 1 0 0 1 1 1 0 Recombinase zinc beta ribbon domain zf-C2H2_6 PF13912.1 EXF80077.1 - 0.33 10.9 9.8 10 6.2 0.4 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger LIM PF00412.17 EXF80077.1 - 0.59 10.2 3.5 4.6 7.3 2.4 2.2 1 1 1 2 2 2 0 LIM domain AOX PF01786.12 EXF80078.1 - 1.9e-79 265.9 0.0 2.4e-79 265.5 0.0 1.1 1 0 0 1 1 1 1 Alternative oxidase ISK_Channel PF02060.10 EXF80078.1 - 0.13 11.8 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 Slow voltage-gated potassium channel DUF1467 PF07330.7 EXF80079.1 - 0.18 11.5 7.3 1 9.1 0.0 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1467) gpUL132 PF11359.3 EXF80079.1 - 0.8 8.9 4.8 1.3 8.3 3.3 1.3 1 0 0 1 1 1 0 Glycoprotein UL132 LAT PF15234.1 EXF80079.1 - 3.2 7.1 5.9 0.67 9.3 1.3 1.8 2 0 0 2 2 2 0 Linker for activation of T-cells eIF3_subunit PF08597.5 EXF80080.1 - 4.3e-65 219.6 20.8 4.8e-65 219.5 14.4 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit PRP4 PF08799.6 EXF80080.1 - 1.2 8.5 5.6 2.3 7.5 3.9 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like CDC27 PF09507.5 EXF80080.1 - 1.9 7.6 26.0 0.19 10.9 12.6 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 HemY_N PF07219.8 EXF80080.1 - 3.3 7.2 5.0 11 5.6 3.5 1.8 1 0 0 1 1 1 0 HemY protein N-terminus Nop53 PF07767.6 EXF80080.1 - 4.3 6.2 26.7 1.4 7.8 13.7 2.1 2 0 0 2 2 2 0 Nop53 (60S ribosomal biogenesis) Plasmodium_Vir PF05795.6 EXF80080.1 - 8 5.5 11.2 14 4.7 7.7 1.7 1 1 1 2 2 2 0 Plasmodium vivax Vir protein EMG1 PF03587.9 EXF80081.1 - 1.7e-78 262.5 0.0 2e-78 262.3 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase PT PF04886.7 EXF80082.1 - 1.3e-06 27.6 30.2 0.048 12.9 4.6 4.6 2 1 0 2 2 2 2 PT repeat Gly-zipper_Omp PF13488.1 EXF80082.1 - 0.0011 18.5 5.8 0.002 17.7 4.0 1.4 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_OmpA PF13436.1 EXF80082.1 - 0.015 14.9 0.9 0.036 13.7 0.6 1.6 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 EXF80082.1 - 0.06 12.8 6.5 0.12 11.9 4.5 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.10 EXF80082.1 - 0.74 9.5 10.7 1.7 8.3 7.4 1.5 1 0 0 1 1 1 0 Glycine zipper 2TM domain Cys_Met_Meta_PP PF01053.15 EXF80083.1 - 1.1e-33 116.1 0.0 1.5e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SPX PF03105.14 EXF80084.1 - 2.8e-43 148.6 0.0 4.3e-43 148.0 0.0 1.3 1 0 0 1 1 1 1 SPX domain zf-C3HC4_4 PF15227.1 EXF80084.1 - 2.5e-08 33.6 9.8 4.8e-08 32.7 6.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EXF80084.1 - 6.5e-08 32.1 11.3 1.3e-07 31.1 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EXF80084.1 - 6.4e-07 29.3 12.4 1.4e-06 28.2 8.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EXF80084.1 - 5.5e-06 25.9 8.7 1.1e-05 25.0 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EXF80084.1 - 1.3e-05 24.7 9.5 3e-05 23.6 6.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EXF80084.1 - 1.7e-05 24.5 10.9 1.7e-05 24.5 7.6 1.8 2 0 0 2 2 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EXF80084.1 - 0.00021 20.9 7.9 0.00064 19.3 5.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 EXF80084.1 - 0.013 15.2 2.7 0.032 14.0 1.8 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein TerY-C PF15616.1 EXF80084.1 - 0.026 14.4 2.0 0.026 14.4 1.4 1.8 2 0 0 2 2 2 0 TerY-C metal binding domain zf-rbx1 PF12678.2 EXF80084.1 - 0.12 12.4 10.3 0.27 11.3 5.5 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger zf-Apc11 PF12861.2 EXF80084.1 - 0.34 10.7 5.8 0.15 11.9 2.0 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EXF80084.1 - 0.4 10.3 10.2 1.4 8.6 7.3 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DnaJ PF00226.26 EXF80085.1 - 7.4e-25 86.4 0.4 7.4e-25 86.4 0.3 2.4 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.3 EXF80085.1 - 6.9e-10 38.7 1.6 1.6e-09 37.6 1.1 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EXF80085.1 - 1.6e-09 37.6 1.8 3.7e-09 36.4 1.3 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EXF80085.1 - 0.00033 20.7 1.6 0.00073 19.6 1.1 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EXF80085.1 - 0.012 15.9 0.7 0.027 14.8 0.5 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_6 PF13912.1 EXF80085.1 - 0.038 13.8 0.6 0.084 12.8 0.5 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EXF80085.1 - 0.067 13.5 0.3 0.16 12.3 0.2 1.7 1 0 0 1 1 1 0 C2H2-type zinc finger DUF2387 PF09526.5 EXF80085.1 - 0.28 11.1 2.4 1.1 9.2 1.6 2.0 1 0 0 1 1 1 0 Probable metal-binding protein (DUF2387) Peptidase_C54 PF03416.14 EXF80086.1 - 9.3e-93 310.3 0.0 1.5e-92 309.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C54 R3H PF01424.17 EXF80087.1 - 8.4e-14 51.0 0.0 1.8e-13 49.9 0.0 1.6 1 0 0 1 1 1 1 R3H domain G-patch PF01585.18 EXF80087.1 - 4.5e-11 42.3 1.2 1.2e-10 41.0 0.8 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EXF80087.1 - 0.00069 19.4 0.5 0.0027 17.5 0.3 2.1 1 0 0 1 1 1 1 DExH-box splicing factor binding site Histone PF00125.19 EXF80088.1 - 1.8e-22 79.2 0.2 2.5e-22 78.7 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EXF80088.1 - 2e-05 24.5 0.0 5.3e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EXF80088.1 - 0.00027 21.1 0.0 0.00046 20.4 0.0 1.3 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A RP-C PF03428.8 EXF80088.1 - 0.012 15.0 0.1 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain DUF1018 PF06252.7 EXF80088.1 - 0.033 14.7 0.5 0.044 14.3 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) SH3_1 PF00018.23 EXF80089.1 - 1.4e-26 91.5 0.0 3.8e-13 48.6 0.0 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.1 EXF80089.1 - 2.2e-18 65.5 0.2 1.8e-08 33.8 0.0 3.1 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.12 EXF80089.1 - 5.8e-13 48.1 0.0 5.2e-08 32.2 0.0 2.5 2 0 0 2 2 2 2 Variant SH3 domain PX PF00787.19 EXF80089.1 - 6.3e-13 48.5 0.0 1.2e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 PX domain PB1 PF00564.19 EXF80089.1 - 6.5e-09 35.3 0.1 9.9e-09 34.7 0.1 1.3 1 0 0 1 1 1 1 PB1 domain Rad60-SLD PF11976.3 EXF80089.1 - 0.17 11.5 0.2 1.1 8.9 0.1 2.2 1 1 1 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Pex14_N PF04695.8 EXF80089.1 - 4 7.5 13.5 0.93 9.5 0.9 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SAC3_GANP PF03399.11 EXF80090.1 - 4.2e-64 215.8 0.2 5.6e-64 215.4 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EXF80090.1 - 0.0027 17.5 0.0 0.0063 16.2 0.0 1.6 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 EAP30 PF04157.11 EXF80091.1 - 2e-56 190.6 0.0 2.8e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EXF80091.1 - 1.7e-16 59.8 0.0 3e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 zf-RanBP PF00641.13 EXF80091.1 - 0.00064 18.7 1.9 0.00064 18.7 1.3 2.6 3 0 0 3 3 3 2 Zn-finger in Ran binding protein and others GRAM PF02893.15 EXF80091.1 - 0.0024 17.3 0.0 0.0053 16.2 0.0 1.5 1 0 0 1 1 1 1 GRAM domain zf-Sec23_Sec24 PF04810.10 EXF80091.1 - 0.0046 16.4 7.7 0.008 15.7 0.2 2.7 2 1 0 2 2 2 1 Sec23/Sec24 zinc finger DZR PF12773.2 EXF80091.1 - 0.016 14.9 0.8 0.016 14.9 0.6 2.1 2 1 0 2 2 2 0 Double zinc ribbon Peptidase_S9 PF00326.16 EXF80093.1 - 2.2e-44 151.2 0.0 3.6e-44 150.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EXF80093.1 - 6.1e-09 35.7 0.0 1.5e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EXF80093.1 - 5.4e-05 21.8 0.1 0.19 10.1 0.0 2.5 2 1 1 3 3 3 2 Acetyl xylan esterase (AXE1) PD40 PF07676.7 EXF80093.1 - 0.0013 18.3 0.1 0.24 11.0 0.0 2.8 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Abhydrolase_3 PF07859.8 EXF80093.1 - 0.0034 16.9 0.0 0.55 9.7 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Glyco_hydro_2 PF00703.16 EXF80094.1 - 3e-09 37.2 0.1 9.1e-09 35.7 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_N PF02837.13 EXF80094.1 - 9.6e-06 25.2 0.0 2.5e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EXF80094.1 - 0.00019 20.4 0.0 0.00033 19.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain PI31_Prot_N PF11566.3 EXF80095.1 - 1.2e-28 99.6 0.0 1.5e-28 99.3 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EXF80095.1 - 5.6e-15 55.7 21.2 5.6e-15 55.7 14.7 3.1 2 2 2 4 4 4 1 PI31 proteasome regulator HORMA PF02301.13 EXF80096.1 - 3e-21 75.8 0.0 4e-21 75.4 0.0 1.1 1 0 0 1 1 1 1 HORMA domain MFS_1 PF07690.11 EXF80097.1 - 1.1e-31 109.9 19.2 1.1e-31 109.9 13.3 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_holin_5 PF06946.6 EXF80097.1 - 0.17 12.0 2.7 5.7 7.1 0.0 2.8 2 0 0 2 2 2 0 Phage holin DUF4231 PF14015.1 EXF80097.1 - 0.21 11.5 0.0 0.21 11.5 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) GIY-YIG PF01541.19 EXF80098.1 - 0.0094 16.3 0.0 0.022 15.0 0.0 1.6 1 0 0 1 1 1 1 GIY-YIG catalytic domain Sin_N PF04801.8 EXF80100.1 - 3.2e-19 69.1 1.9 1.1e-18 67.3 1.3 1.8 1 1 0 1 1 1 1 Sin-like protein conserved region PAT1 PF09770.4 EXF80101.1 - 2.5e-236 786.7 15.9 2.9e-236 786.5 11.0 1.0 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Glyco_transf_15 PF01793.11 EXF80102.1 - 2.7e-145 483.4 3.5 3.4e-145 483.1 2.4 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase CDI PF02234.14 EXF80102.1 - 0.019 14.7 0.6 0.019 14.7 0.4 2.0 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor Ribosom_S12_S23 PF00164.20 EXF80103.1 - 1.9e-40 137.0 0.9 2.4e-40 136.7 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Acyl-CoA_dh_1 PF00441.19 EXF80104.1 - 1.4e-41 142.0 4.2 2.3e-41 141.4 2.9 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EXF80104.1 - 1.9e-28 99.3 0.3 5.1e-28 97.9 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EXF80104.1 - 6.1e-18 64.0 0.0 1.2e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EXF80104.1 - 1.5e-17 64.1 0.9 2.9e-17 63.1 0.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EXF80104.1 - 0.0086 15.4 0.1 0.039 13.3 0.1 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal HR1 PF02185.11 EXF80105.1 - 1.9e-26 91.5 21.6 2.2e-16 59.3 3.1 2.8 3 0 0 3 3 3 2 Hr1 repeat C1_1 PF00130.17 EXF80105.1 - 5.3e-20 70.9 31.5 1.2e-11 44.1 7.9 2.2 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Pkinase_C PF00433.19 EXF80105.1 - 0.0005 20.5 1.5 0.0015 18.9 1.1 2.0 1 1 0 1 1 1 1 Protein kinase C terminal domain FYVE_2 PF02318.11 EXF80105.1 - 5.2 7.0 20.1 5.7 6.8 4.7 2.8 1 1 1 2 2 2 0 FYVE-type zinc finger PHD PF00628.24 EXF80105.1 - 6.8 6.4 27.4 0.036 13.7 5.7 2.5 2 0 0 2 2 2 0 PHD-finger She9_MDM33 PF05546.6 EXF80106.1 - 6.2e-80 267.6 4.0 1e-79 266.9 2.8 1.3 1 0 0 1 1 1 1 She9 / Mdm33 family PsbH PF00737.15 EXF80106.1 - 0.15 11.6 0.4 0.3 10.6 0.3 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein Nif11 PF07862.6 EXF80106.1 - 0.28 11.1 0.1 0.28 11.1 0.1 3.1 4 0 0 4 4 4 0 Nitrogen fixation protein of unknown function DUF2235 PF09994.4 EXF80107.1 - 1.2e-69 234.7 0.0 1.6e-69 234.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EXF80107.1 - 0.041 13.6 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family SBP_bac_6 PF13343.1 EXF80108.1 - 3.3e-17 62.6 0.0 5e-17 62.0 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.1 EXF80108.1 - 3.9e-07 29.9 0.0 6.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.20 EXF80108.1 - 0.0064 16.2 0.3 0.013 15.2 0.2 1.8 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein GST_N_3 PF13417.1 EXF80110.1 - 0.0022 18.1 0.0 0.0043 17.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EXF80110.1 - 0.011 15.6 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EXF80110.1 - 0.027 14.3 0.1 0.058 13.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Ank_2 PF12796.2 EXF80111.1 - 1.1e-12 48.1 0.0 1.3e-08 35.0 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EXF80111.1 - 8.1e-08 31.7 1.0 0.029 14.1 0.0 3.7 3 1 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EXF80111.1 - 4.9e-06 26.9 0.1 0.00033 21.1 0.0 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF80111.1 - 4.1e-05 23.6 0.4 0.0019 18.4 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF80111.1 - 0.00031 20.7 0.2 11 6.6 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat Sulfatase PF00884.18 EXF80113.1 - 1e-73 248.2 0.0 1.2e-73 247.9 0.0 1.1 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 EXF80113.1 - 0.0016 16.9 0.0 0.0022 16.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF229) Phosphodiest PF01663.17 EXF80113.1 - 0.0036 16.6 0.1 0.18 11.0 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase RNA_pol_Rpb1_4 PF05000.12 EXF80113.1 - 0.027 14.1 0.1 0.062 13.0 0.1 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 4 Sugar_tr PF00083.19 EXF80114.1 - 7.2e-57 192.9 11.3 8.9e-57 192.6 7.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF80114.1 - 2.2e-11 43.0 15.5 2.2e-11 43.0 10.7 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Pox_A14 PF05767.7 EXF80114.1 - 0.0014 18.5 0.1 0.0051 16.7 0.0 2.0 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 Trep_Strep PF09605.5 EXF80114.1 - 7.1 6.2 12.2 0.12 12.0 2.5 2.4 3 0 0 3 3 3 0 Hypothetical bacterial integral membrane protein (Trep_Strep) Nucleo_P87 PF07267.6 EXF80118.1 - 8.7 4.8 7.1 15 4.1 4.9 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Sugar_tr PF00083.19 EXF80119.1 - 4e-65 220.1 13.8 1.7e-63 214.7 9.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF80119.1 - 2.6e-19 69.1 23.3 2.4e-15 56.0 6.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF80119.1 - 8.9e-07 27.4 1.0 1.5e-06 26.7 0.7 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1_like PF12832.2 EXF80119.1 - 0.0095 15.7 1.8 0.17 11.7 0.0 3.5 3 0 0 3 3 3 1 MFS_1 like family p450 PF00067.17 EXF80120.1 - 1e-55 189.1 0.0 5e-50 170.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Reticulon PF02453.12 EXF80120.1 - 0.026 14.1 0.0 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 Reticulon GMC_oxred_N PF00732.14 EXF80123.1 - 8.7e-30 103.8 0.0 1.8e-26 92.9 0.0 3.0 1 1 1 2 2 2 2 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF80123.1 - 2.3e-29 102.5 0.0 4.1e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EXF80123.1 - 0.00029 20.8 0.0 0.00095 19.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF80123.1 - 0.00033 20.5 0.0 0.00071 19.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF80123.1 - 0.00051 19.0 0.1 0.0014 17.5 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.19 EXF80123.1 - 0.0015 17.4 0.1 0.0082 15.0 0.1 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EXF80123.1 - 0.0053 15.2 0.0 0.0077 14.7 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 EXF80123.1 - 0.0077 15.3 0.0 0.014 14.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF80123.1 - 0.0081 15.1 0.3 0.017 14.0 0.1 1.6 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EXF80123.1 - 0.087 12.8 0.0 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EXF80123.1 - 0.088 11.8 0.5 0.14 11.2 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EXF80123.1 - 0.099 13.0 0.2 0.26 11.6 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF80123.1 - 0.13 11.3 0.1 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_Gly3P_dh_N PF01210.18 EXF80123.1 - 0.21 11.3 0.2 0.46 10.2 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus COesterase PF00135.23 EXF80124.1 - 6.4e-101 338.6 0.0 1.6e-100 337.3 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF80124.1 - 1.5e-09 37.7 0.0 7.5e-09 35.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EXF80124.1 - 0.0014 17.8 0.0 0.0025 17.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EXF80124.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family peroxidase PF00141.18 EXF80125.1 - 2.9e-23 82.5 0.6 4.8e-23 81.8 0.4 1.3 1 0 0 1 1 1 1 Peroxidase GMC_oxred_C PF05199.8 EXF80126.1 - 5.7e-12 46.1 0.1 1.2e-11 45.1 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase Ribonuclease_T2 PF00445.13 EXF80127.1 - 3.6e-17 62.6 2.4 1.1e-16 60.9 0.0 2.6 2 1 1 3 3 3 1 Ribonuclease T2 family FAD_binding_4 PF01565.18 EXF80127.1 - 2.6e-13 49.6 0.0 5.2e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF80127.1 - 8.8e-07 28.7 0.0 2.2e-06 27.4 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like IF-2B PF01008.12 EXF80128.1 - 2.3e-43 148.2 0.0 3.1e-43 147.7 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family DeoRC PF00455.17 EXF80128.1 - 0.027 14.0 0.0 0.56 9.8 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain DUF1681 PF07933.9 EXF80129.1 - 7.2e-61 204.4 0.0 1.2e-60 203.7 0.0 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1681) XPG_I_2 PF12813.2 EXF80130.1 - 0.056 12.9 0.1 0.077 12.4 0.1 1.2 1 0 0 1 1 1 0 XPG domain containing Fer4_12 PF13353.1 EXF80131.1 - 7.8e-06 26.0 0.2 1.5e-05 25.1 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Radical_SAM PF04055.16 EXF80131.1 - 1.8e-05 24.9 0.0 3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 EXF80131.1 - 0.00051 20.0 0.2 0.0012 18.8 0.1 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Kazal_2 PF07648.10 EXF80131.1 - 0.019 14.8 2.4 0.019 14.8 1.6 2.2 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain Glycos_trans_3N PF02885.12 EXF80131.1 - 0.11 12.0 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family, helical bundle domain GMC_oxred_N PF00732.14 EXF80132.1 - 1.9e-66 224.2 0.0 3.4e-66 223.3 0.0 1.4 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF80132.1 - 1.6e-30 106.2 0.0 2.8e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EXF80132.1 - 6.4e-05 22.8 0.0 0.00018 21.4 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF80132.1 - 0.00012 21.1 0.1 0.001 18.0 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EXF80132.1 - 0.0035 17.4 0.0 0.13 12.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF80132.1 - 0.0041 16.0 0.0 0.013 14.3 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain Lycopene_cycl PF05834.7 EXF80132.1 - 0.025 13.5 0.1 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Thi4 PF01946.12 EXF80132.1 - 0.036 13.1 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EXF80132.1 - 0.043 13.5 0.1 0.083 12.6 0.1 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EXF80132.1 - 0.13 10.7 0.1 0.29 9.5 0.0 1.6 2 0 0 2 2 2 0 HI0933-like protein AAA PF00004.24 EXF80133.1 - 3.1e-11 43.6 0.0 6.5e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EXF80133.1 - 2.1e-06 27.9 0.0 6e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EXF80133.1 - 9.3e-06 25.4 0.0 1.8e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EXF80133.1 - 4.3e-05 22.6 0.0 8.1e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EXF80133.1 - 0.00012 21.7 0.0 0.00052 19.7 0.0 2.1 2 0 0 2 2 1 1 Part of AAA domain Rad17 PF03215.10 EXF80133.1 - 0.00052 18.8 0.0 0.0009 18.0 0.0 1.2 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EXF80133.1 - 0.00063 19.6 0.0 0.0013 18.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EXF80133.1 - 0.0011 18.8 0.0 0.003 17.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EXF80133.1 - 0.0029 18.4 0.0 0.011 16.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EXF80133.1 - 0.013 14.7 0.0 0.028 13.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 EXF80133.1 - 0.022 14.4 0.7 0.084 12.5 0.1 2.1 1 1 1 2 2 2 0 NTPase AAA_16 PF13191.1 EXF80133.1 - 0.023 14.7 0.2 0.061 13.3 0.0 1.8 2 0 0 2 2 1 0 AAA ATPase domain AAA_18 PF13238.1 EXF80133.1 - 0.025 14.8 0.0 0.059 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EXF80133.1 - 0.026 13.6 0.0 0.052 12.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 EXF80133.1 - 0.051 13.1 0.0 0.13 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EXF80133.1 - 0.058 12.2 0.0 0.092 11.5 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.1 EXF80133.1 - 0.062 13.2 0.0 0.18 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EXF80133.1 - 0.07 12.2 0.0 1.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EXF80133.1 - 0.083 12.3 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein KTI12 PF08433.5 EXF80133.1 - 0.084 12.0 0.1 0.17 11.0 0.1 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ABC_tran PF00005.22 EXF80133.1 - 0.084 13.1 0.1 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 ABC transporter HIT PF01230.18 EXF80134.1 - 5.7e-22 78.0 0.1 9.9e-22 77.3 0.0 1.3 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EXF80134.1 - 3.1e-06 27.4 0.1 6.1e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Ferrochelatase PF00762.14 EXF80135.1 - 6e-91 304.6 0.0 7.2e-91 304.4 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase Ku PF02735.11 EXF80136.1 - 1.5e-38 132.2 0.0 4.4e-38 130.7 0.0 1.8 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EXF80136.1 - 3.5e-33 114.9 0.0 5e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 EXF80136.1 - 1.6e-15 57.4 0.8 4.8e-15 55.8 0.5 1.9 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm SAP PF02037.22 EXF80136.1 - 2.2e-10 39.7 0.2 2.9e-09 36.2 0.1 2.3 2 0 0 2 2 2 1 SAP domain VWA PF00092.23 EXF80136.1 - 0.078 12.6 0.0 4.6 6.9 0.0 2.2 2 0 0 2 2 2 0 von Willebrand factor type A domain MFS_1 PF07690.11 EXF80139.1 - 3.8e-20 71.8 33.5 7.2e-16 57.8 10.2 2.9 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF80139.1 - 1.3e-05 23.9 5.7 1.3e-05 23.9 4.0 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter Myb_Cef PF11831.3 EXF80140.1 - 1.5e-60 204.2 9.2 1.5e-60 204.2 6.4 3.5 3 0 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-bind_6 PF13921.1 EXF80140.1 - 1.4e-21 76.3 8.4 4.8e-15 55.3 2.3 3.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EXF80140.1 - 2.3e-21 75.5 4.7 2.5e-10 40.2 0.3 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.3 EXF80140.1 - 5 7.0 7.7 1 9.2 0.0 3.4 3 1 1 4 4 4 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MFS_1 PF07690.11 EXF80141.1 - 1.6e-40 138.9 57.7 2.3e-40 138.4 36.5 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF80141.1 - 1.7e-12 46.7 13.2 1.7e-12 46.7 9.1 3.1 2 1 2 4 4 4 1 Sugar (and other) transporter TRI12 PF06609.8 EXF80141.1 - 3.7e-09 35.3 16.0 5.7e-09 34.7 11.1 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) F-box-like PF12937.2 EXF80142.1 - 0.021 14.5 0.0 0.14 11.8 0.0 2.4 1 1 0 1 1 1 0 F-box-like Mito_carr PF00153.22 EXF80143.1 - 9.6e-19 66.8 0.0 2.7e-11 43.0 0.0 3.7 4 1 0 4 4 4 2 Mitochondrial carrier protein Lactamase_B PF00753.22 EXF80144.1 - 1.5e-08 34.5 0.1 2.5e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EXF80144.1 - 0.041 13.4 0.0 0.058 12.9 0.0 1.4 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Abhydrolase_4 PF08386.5 EXF80145.1 - 2.1e-21 75.7 0.0 6.5e-21 74.1 0.0 1.8 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_1 PF00561.15 EXF80145.1 - 7.5e-13 48.5 0.0 2.2e-11 43.7 0.0 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EXF80145.1 - 3e-10 40.3 1.3 1.5e-09 38.0 0.9 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EXF80145.1 - 0.013 14.9 0.0 0.027 13.9 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) T5orf172 PF10544.4 EXF80146.1 - 1.1e-12 48.2 0.2 2.3e-12 47.1 0.1 1.5 1 0 0 1 1 1 1 T5orf172 domain MUG113 PF13455.1 EXF80146.1 - 1e-10 41.8 0.3 1.9e-10 41.0 0.2 1.4 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 FMO-like PF00743.14 EXF80147.1 - 5.8e-29 100.6 0.0 9.6e-18 63.6 0.0 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EXF80147.1 - 4.7e-12 46.4 0.1 3.1e-11 43.7 0.1 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF80147.1 - 7.9e-07 29.0 0.4 3.2e-06 27.0 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EXF80147.1 - 4.6e-05 23.2 0.1 0.00023 20.9 0.1 2.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding K_oxygenase PF13434.1 EXF80147.1 - 0.00016 20.6 0.1 0.023 13.6 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EXF80147.1 - 0.0075 16.1 0.0 2.7 7.8 0.2 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF80147.1 - 0.016 14.0 1.3 0.025 13.4 0.3 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EXF80147.1 - 0.041 12.3 0.3 0.061 11.7 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Semialdhyde_dh PF01118.19 EXF80147.1 - 0.045 14.0 0.0 0.19 12.0 0.0 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain OCD_Mu_crystall PF02423.10 EXF80147.1 - 0.051 12.3 0.1 0.079 11.7 0.1 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Thi4 PF01946.12 EXF80147.1 - 0.19 10.8 0.1 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Thi4 family CMD PF02627.15 EXF80148.1 - 3e-18 65.4 0.1 5.1e-18 64.6 0.1 1.3 1 0 0 1 1 1 1 Carboxymuconolactone decarboxylase family Abhydrolase_5 PF12695.2 EXF80150.1 - 9.3e-15 54.6 0.2 1.6e-14 53.8 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PAF-AH_p_II PF03403.8 EXF80150.1 - 4e-14 51.6 0.0 7.1e-07 27.8 0.0 2.4 1 1 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_6 PF12697.2 EXF80150.1 - 3.6e-10 40.1 0.5 7.5e-10 39.0 0.3 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EXF80150.1 - 5.6e-07 28.7 0.0 1.1e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_2 PF02230.11 EXF80150.1 - 0.0015 17.9 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Chlorophyllase PF07224.6 EXF80150.1 - 0.0015 17.3 0.0 0.0063 15.3 0.0 1.9 1 1 0 1 1 1 1 Chlorophyllase Peptidase_S9 PF00326.16 EXF80150.1 - 0.021 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family PhoPQ_related PF10142.4 EXF80150.1 - 0.075 11.5 0.0 2.8 6.3 0.0 2.1 2 0 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein Abhydrolase_1 PF00561.15 EXF80150.1 - 0.083 12.4 0.1 0.19 11.2 0.1 1.6 1 1 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.20 EXF80150.1 - 0.099 12.2 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) NAD_binding_2 PF03446.10 EXF80151.1 - 5.3e-14 52.3 0.2 1.1e-13 51.3 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EXF80151.1 - 2.7e-07 30.9 0.0 6.5e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EXF80151.1 - 7.3e-07 28.5 0.0 2.6e-06 26.7 0.0 1.7 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EXF80151.1 - 0.00043 20.0 1.0 0.0048 16.6 0.7 2.1 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_10 PF13460.1 EXF80151.1 - 0.00044 20.3 0.1 0.00099 19.1 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EXF80151.1 - 0.003 16.8 0.0 0.0046 16.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family UDPG_MGDP_dh_N PF03721.9 EXF80151.1 - 0.18 11.1 0.3 1.6 8.0 0.2 2.2 1 1 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain zf-C2H2_4 PF13894.1 EXF80152.1 - 8.3e-05 22.6 17.4 0.15 12.4 0.5 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF80152.1 - 0.012 15.8 2.4 0.012 15.8 1.6 3.9 4 0 0 4 4 4 0 Zinc finger, C2H2 type TetR PF13972.1 EXF80152.1 - 0.049 13.0 0.3 0.077 12.4 0.2 1.2 1 0 0 1 1 1 0 Bacterial transcriptional repressor zf-C2H2_jaz PF12171.3 EXF80152.1 - 0.052 13.7 2.8 7.2 6.8 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding RseA_C PF03873.8 EXF80152.1 - 2.1 8.3 4.7 0.67 9.8 0.2 2.2 2 0 0 2 2 2 0 Anti sigma-E protein RseA, C-terminal domain SnoaL PF07366.7 EXF80153.1 - 5.3e-05 22.8 0.1 6.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EXF80153.1 - 0.00025 21.4 0.2 0.00036 20.9 0.1 1.3 1 0 0 1 1 1 1 SnoaL-like domain Rib_5-P_isom_A PF06026.9 EXF80154.1 - 8.1e-37 126.1 0.0 3.4e-35 120.9 0.0 2.1 1 1 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) DeoRC PF00455.17 EXF80154.1 - 0.013 15.1 0.1 3.3 7.3 0.0 2.2 2 0 0 2 2 2 0 DeoR C terminal sensor domain FAD_binding_4 PF01565.18 EXF80155.1 - 8.2e-19 67.4 2.4 2.5e-18 65.8 1.2 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EXF80155.1 - 0.074 12.9 0.1 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like ATP-synt_J PF04911.7 EXF80156.1 - 0.016 14.6 0.8 0.19 11.1 0.0 2.8 2 1 0 2 2 2 0 ATP synthase j chain MFS_1 PF07690.11 EXF80157.1 - 5.2e-38 130.6 47.0 5.2e-38 130.6 32.5 1.9 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EXF80157.1 - 5.2e-15 54.6 26.6 1.2e-14 53.4 18.3 1.4 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1418 PF07214.7 EXF80157.1 - 0.014 14.9 0.4 0.045 13.3 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1418) UPF0233 PF06781.7 EXF80157.1 - 0.81 9.3 6.8 37 4.0 0.0 3.8 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0233) WD40 PF00400.27 EXF80158.1 - 8.5e-19 66.6 2.6 0.0016 18.2 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat HpcH_HpaI PF03328.9 EXF80159.1 - 2.8e-26 91.7 0.0 5.1e-26 90.9 0.0 1.4 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family NMD3 PF04981.8 EXF80160.1 - 7e-71 238.0 3.9 9.4e-71 237.6 2.7 1.2 1 0 0 1 1 1 1 NMD3 family DUF35_N PF12172.3 EXF80160.1 - 0.0071 16.2 0.2 1.6 8.7 0.0 2.6 2 0 0 2 2 2 2 Rubredoxin-like zinc ribbon domain (DUF35_N) DZR PF12773.2 EXF80160.1 - 5.3 6.9 8.6 17 5.3 4.1 2.8 2 1 0 2 2 2 0 Double zinc ribbon RRM_6 PF14259.1 EXF80161.1 - 4.5e-08 32.9 0.0 1.6e-07 31.1 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EXF80161.1 - 8.5e-08 31.7 0.0 1.9e-05 24.2 0.0 2.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF80161.1 - 0.0011 18.7 0.0 0.022 14.5 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC45 PF02724.9 EXF80161.1 - 0.024 12.7 9.0 0.037 12.0 6.2 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EXF80161.1 - 0.53 8.1 25.1 0.0051 14.8 11.2 1.8 2 0 0 2 2 2 0 Nop14-like family eIF-3c_N PF05470.7 EXF80161.1 - 4 5.3 8.4 0.68 7.9 2.7 1.8 1 1 2 3 3 3 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Aldedh PF00171.17 EXF80162.1 - 1.5e-134 448.8 0.0 1.8e-134 448.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EXF80162.1 - 6.5e-06 25.1 0.0 1.7e-05 23.7 0.0 1.5 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EXF80162.1 - 0.075 12.2 0.0 6.4 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) WD40 PF00400.27 EXF80163.1 - 1.6e-06 27.7 16.6 0.15 12.0 0.1 6.6 6 1 0 6 6 6 3 WD domain, G-beta repeat AMP-binding PF00501.23 EXF80164.1 - 1.1e-80 271.0 0.0 1.4e-80 270.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme MARVEL PF01284.18 EXF80165.1 - 5e-19 68.5 14.8 6.3e-19 68.2 10.2 1.1 1 0 0 1 1 1 1 Membrane-associating domain Cys_Met_Meta_PP PF01053.15 EXF80166.1 - 2.8e-149 496.6 0.0 3.1e-149 496.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EXF80166.1 - 3.4e-15 55.9 0.4 5.6e-15 55.2 0.3 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EXF80166.1 - 1.2e-10 40.8 0.0 1.9e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EXF80166.1 - 2.2e-08 33.5 0.0 4.3e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EXF80166.1 - 6.2e-08 31.7 0.6 1.6e-07 30.4 0.4 1.5 1 1 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 EXF80166.1 - 0.00015 20.2 0.1 0.0002 19.7 0.1 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase SLA_LP_auto_ag PF05889.8 EXF80166.1 - 0.013 14.0 0.0 0.018 13.5 0.0 1.1 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) GDC-P PF02347.11 EXF80166.1 - 0.031 12.9 0.1 0.045 12.4 0.0 1.2 1 0 0 1 1 1 0 Glycine cleavage system P-protein CPSase_L_D2 PF02786.12 EXF80166.1 - 0.13 11.5 0.1 0.23 10.7 0.0 1.4 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain DUF2012 PF09430.5 EXF80167.1 - 6.2e-23 80.9 0.0 8e-23 80.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) HNH_2 PF13391.1 EXF80168.1 - 0.077 12.7 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 HNH endonuclease TRF PF08558.5 EXF80169.1 - 8.8e-24 84.1 1.1 8.8e-24 84.1 0.7 1.9 2 0 0 2 2 2 1 Telomere repeat binding factor (TRF) Myb_DNA-binding PF00249.26 EXF80169.1 - 6.2e-06 26.1 0.1 1.3e-05 25.0 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Spore_GerAC PF05504.6 EXF80169.1 - 2.5 7.8 6.1 5.9 6.6 4.2 1.5 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal Hydantoinase_B PF02538.9 EXF80170.1 - 1.7e-184 613.9 0.0 2.3e-184 613.5 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EXF80170.1 - 7.3e-95 317.3 0.1 1.5e-94 316.3 0.1 1.6 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EXF80170.1 - 8.7e-56 188.1 0.2 5.5e-54 182.3 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Proteasome_A_N PF10584.4 EXF80170.1 - 0.036 13.4 0.2 0.08 12.2 0.2 1.5 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature Aminotran_1_2 PF00155.16 EXF80171.1 - 2.9e-69 233.7 0.0 3.3e-69 233.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EXF80171.1 - 0.0066 15.0 0.0 0.011 14.3 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase DHDPS PF00701.17 EXF80172.1 - 6.6e-50 169.3 0.0 7.3e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family PEP_mutase PF13714.1 EXF80172.1 - 1.7e-05 24.1 0.0 2.6e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Peripla_BP_1 PF00532.16 EXF80172.1 - 0.11 11.6 0.1 0.18 10.9 0.1 1.4 1 1 0 1 1 1 0 Periplasmic binding proteins and sugar binding domain of LacI family DUF2188 PF09954.4 EXF80172.1 - 0.14 12.0 0.4 0.37 10.7 0.2 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) His_Phos_2 PF00328.17 EXF80173.1 - 6.8e-07 28.9 0.0 1.3e-06 27.9 0.0 1.4 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) DASH_Dad1 PF08649.5 EXF80174.1 - 9.8e-24 82.8 1.7 1.2e-23 82.5 1.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad1 WVELL PF14043.1 EXF80174.1 - 0.053 13.1 0.1 0.091 12.3 0.1 1.5 1 1 0 1 1 1 0 WVELL protein DASH_Dad4 PF08650.5 EXF80174.1 - 0.071 13.0 0.3 0.1 12.5 0.2 1.3 1 0 0 1 1 1 0 DASH complex subunit Dad4 Glutaredoxin2_C PF04399.8 EXF80174.1 - 0.076 12.5 0.2 0.13 11.8 0.1 1.4 1 1 0 1 1 1 0 Glutaredoxin 2, C terminal domain Ras PF00071.17 EXF80176.1 - 8.4e-48 161.8 0.0 1.1e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EXF80176.1 - 7.5e-12 45.8 0.0 1.2e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EXF80176.1 - 4.9e-05 22.6 0.0 9.3e-05 21.7 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Skp1_POZ PF03931.10 EXF80177.1 - 1.5e-11 44.2 0.0 1.9e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain DBR1 PF05011.8 EXF80178.1 - 1.3e-46 158.0 0.3 5.5e-46 156.0 0.0 1.9 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EXF80178.1 - 1.3e-05 24.7 0.1 2.3e-05 23.9 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase LSM PF01423.17 EXF80179.1 - 4.7e-19 67.7 0.1 6e-19 67.3 0.1 1.1 1 0 0 1 1 1 1 LSM domain PRMT5 PF05185.11 EXF80180.1 - 3.8e-162 540.2 0.0 5e-162 539.8 0.0 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase OB_NTP_bind PF07717.11 EXF80181.1 - 1.1e-26 92.8 0.0 4.3e-26 90.9 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EXF80181.1 - 4.7e-23 81.1 0.0 1.3e-22 79.6 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EXF80181.1 - 4.7e-12 45.6 0.0 1.9e-11 43.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EXF80181.1 - 8e-08 31.9 0.2 3e-07 30.0 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EXF80181.1 - 2.2e-06 27.8 0.0 6.1e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EXF80181.1 - 9.3e-05 21.4 0.0 0.00018 20.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein SRP54 PF00448.17 EXF80181.1 - 9.5e-05 21.9 0.1 0.00029 20.3 0.1 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ResIII PF04851.10 EXF80181.1 - 0.0043 16.9 0.1 1.7 8.4 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.9 EXF80181.1 - 0.0098 15.6 0.2 0.022 14.5 0.1 1.6 1 0 0 1 1 1 1 Flavivirus DEAD domain Response_reg PF00072.19 EXF80181.1 - 0.096 12.7 2.2 0.17 11.9 0.1 2.5 4 0 0 4 4 4 0 Response regulator receiver domain adh_short PF00106.20 EXF80182.1 - 2.9e-20 72.8 1.4 2.8e-19 69.6 1.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF80182.1 - 2.5e-06 27.2 0.7 4e-06 26.6 0.5 1.3 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF80182.1 - 2.8e-06 27.3 0.0 3.5e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 EXF80182.1 - 0.0049 16.5 0.4 0.0068 16.0 0.3 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EXF80182.1 - 0.082 12.3 0.1 0.14 11.5 0.1 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EXF80182.1 - 0.13 12.6 0.3 0.21 12.0 0.2 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent FAD_binding_3 PF01494.14 EXF80183.1 - 3.5e-22 78.9 0.0 6e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain ADC PF06314.6 EXF80183.1 - 5.1e-17 62.0 0.0 9.7e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) DAO PF01266.19 EXF80183.1 - 2e-08 33.5 2.6 1.3e-06 27.6 0.5 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF80183.1 - 3e-06 27.1 1.0 5.6e-06 26.2 0.1 2.0 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EXF80183.1 - 0.00029 20.6 0.4 0.001 18.8 0.3 1.9 1 1 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EXF80183.1 - 0.0011 18.8 0.1 0.0023 17.8 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF80183.1 - 0.013 14.3 1.0 0.025 13.4 0.7 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EXF80183.1 - 0.016 15.6 0.1 0.049 14.0 0.1 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EXF80183.1 - 0.016 14.8 0.1 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EXF80183.1 - 0.017 13.9 0.2 0.026 13.3 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 EXF80183.1 - 0.036 12.5 0.1 0.056 11.9 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EXF80183.1 - 0.071 12.1 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.11 EXF80183.1 - 0.13 11.7 0.3 0.24 10.8 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Cupin_2 PF07883.6 EXF80184.1 - 2.6e-08 33.2 0.1 7.2e-08 31.8 0.0 1.8 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.17 EXF80184.1 - 0.00016 21.1 0.0 0.00022 20.6 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EXF80184.1 - 0.0043 16.4 0.0 0.0071 15.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) ABC_membrane PF00664.18 EXF80185.1 - 5.6e-75 252.2 35.4 6.8e-42 143.7 6.8 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EXF80185.1 - 8.7e-67 223.6 0.1 2.6e-33 115.2 0.0 3.3 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EXF80185.1 - 1.2e-14 54.0 7.5 8.2e-08 31.7 0.9 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EXF80185.1 - 8.8e-11 42.2 0.5 0.0087 16.0 0.0 4.1 3 1 0 3 3 3 3 AAA domain ABC_ATPase PF09818.4 EXF80185.1 - 1.4e-09 37.0 0.2 0.0084 14.7 0.0 3.7 3 1 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.1 EXF80185.1 - 1.1e-08 35.3 3.0 9.6e-05 22.4 0.0 3.7 3 1 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 EXF80185.1 - 2.7e-07 30.0 1.7 0.00026 20.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EXF80185.1 - 3.2e-07 29.6 0.1 0.0094 15.1 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EXF80185.1 - 2.2e-06 28.5 0.4 0.0041 17.9 0.2 2.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EXF80185.1 - 8.4e-06 25.9 2.3 0.11 12.6 0.1 3.6 3 1 0 3 3 3 2 AAA domain AAA_30 PF13604.1 EXF80185.1 - 1.9e-05 24.3 2.3 0.095 12.2 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EXF80185.1 - 5.1e-05 22.7 1.7 0.34 10.2 0.0 3.6 4 0 0 4 4 4 2 AAA domain DUF3987 PF13148.1 EXF80185.1 - 0.00012 20.8 2.1 0.00025 19.7 0.7 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) ATP-synt_ab PF00006.20 EXF80185.1 - 0.00013 21.5 0.1 0.31 10.4 0.0 2.7 2 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.24 EXF80185.1 - 0.00016 21.8 1.9 12 6.1 0.2 4.6 4 1 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EXF80185.1 - 0.00044 20.1 0.0 0.025 14.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EXF80185.1 - 0.00045 20.0 1.3 0.62 10.0 0.1 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_15 PF13175.1 EXF80185.1 - 0.00047 19.3 0.3 0.49 9.3 0.1 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.1 EXF80185.1 - 0.00052 19.9 0.4 0.58 10.0 0.0 3.4 4 0 0 4 4 3 1 AAA domain AAA_5 PF07728.9 EXF80185.1 - 0.00053 19.7 0.2 1.5 8.5 0.0 3.3 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EXF80185.1 - 0.00087 19.0 0.1 0.097 12.4 0.0 3.3 3 0 0 3 3 2 1 Part of AAA domain PRK PF00485.13 EXF80185.1 - 0.0012 18.4 0.0 0.97 8.9 0.0 2.3 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EXF80185.1 - 0.0016 18.7 0.2 0.3 11.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EXF80185.1 - 0.0031 16.9 0.3 0.046 13.1 0.0 2.9 3 0 0 3 3 3 1 AAA-like domain AAA_23 PF13476.1 EXF80185.1 - 0.0048 17.2 8.8 0.4 10.9 3.8 3.0 2 1 1 3 3 2 1 AAA domain Zeta_toxin PF06414.7 EXF80185.1 - 0.005 15.9 0.7 3.2 6.8 0.1 2.8 3 0 0 3 3 3 1 Zeta toxin NB-ARC PF00931.17 EXF80185.1 - 0.036 12.9 0.1 2.2 7.0 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_28 PF13521.1 EXF80185.1 - 0.042 13.8 0.0 10 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EXF80185.1 - 0.052 13.7 0.1 17 5.6 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Miro PF08477.8 EXF80185.1 - 0.055 13.9 0.3 17 5.9 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein Synapsin_N PF10581.4 EXF80185.1 - 0.067 13.0 0.0 0.97 9.3 0.0 2.6 3 0 0 3 3 3 0 Synapsin N-terminal DUF3094 PF11293.3 EXF80185.1 - 0.17 11.3 1.2 7.6 6.0 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3094) tRNA-synt_His PF13393.1 EXF80186.1 - 1.7e-40 139.0 0.0 3.2e-34 118.3 0.0 2.2 2 0 0 2 2 2 2 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EXF80186.1 - 8.8e-19 67.7 0.0 1.3e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EXF80186.1 - 5.9e-11 42.1 0.0 1.1e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EXF80186.1 - 0.0034 16.2 0.0 0.02 13.7 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) Herpes_capsid PF06112.6 EXF80187.1 - 9.6 6.2 15.3 0.22 11.5 4.6 2.2 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein Ldh_1_N PF00056.18 EXF80188.1 - 1e-43 148.5 0.1 3.5e-43 146.8 0.0 1.8 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.13 EXF80188.1 - 1.8e-41 141.7 0.0 2.6e-41 141.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain 3Beta_HSD PF01073.14 EXF80188.1 - 3.5e-05 22.6 0.0 5.1e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.11 EXF80188.1 - 0.089 12.0 0.0 0.3 10.3 0.0 1.8 2 0 0 2 2 2 0 Family 4 glycosyl hydrolase Hydrolase PF00702.21 EXF80189.1 - 1.4e-21 77.9 0.0 4.9e-21 76.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EXF80189.1 - 1.8e-20 72.9 0.0 4.3e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EXF80189.1 - 8.1e-19 68.5 0.0 1.7e-18 67.5 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EXF80189.1 - 2.7e-06 27.2 0.0 1.7e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EXF80189.1 - 0.026 14.1 0.1 0.25 10.8 0.1 2.4 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF4059 PF13268.1 EXF80189.1 - 0.17 12.0 1.6 12 6.2 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4059) SIR2 PF02146.12 EXF80191.1 - 2.7e-30 105.4 0.0 2.6e-10 40.3 0.0 3.2 3 0 0 3 3 3 3 Sir2 family Sugar_tr PF00083.19 EXF80193.1 - 5.5e-82 275.7 24.9 6.3e-82 275.5 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF80193.1 - 3.7e-18 65.3 35.6 3.8e-16 58.7 19.9 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 EXF80194.1 - 1.1e-17 63.8 0.0 1.6e-17 63.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF80194.1 - 0.013 15.3 9.2 0.013 15.3 6.3 2.4 2 0 0 2 2 2 0 Fungal Zn(2)-Cys(6) binuclear cluster domain Melibiase PF02065.13 EXF80195.1 - 7.7e-40 136.7 0.0 1.8e-22 79.5 0.0 2.1 1 1 0 2 2 2 2 Melibiase MDM31_MDM32 PF08118.6 EXF80197.1 - 1.6e-182 607.5 0.8 6.7e-182 605.4 0.6 1.8 1 1 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Chorion_2 PF03964.10 EXF80197.1 - 0.15 12.5 0.1 0.15 12.5 0.0 2.5 2 1 0 2 2 2 0 Chorion family 2 DUF3827 PF12877.2 EXF80197.1 - 0.32 9.0 3.5 0.48 8.4 2.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) KH_1 PF00013.24 EXF80198.1 - 4.6e-05 22.9 0.9 9.3e-05 21.9 0.6 1.5 1 0 0 1 1 1 1 KH domain eIF-3_zeta PF05091.7 EXF80199.1 - 4.7e-191 635.9 0.0 5.7e-191 635.6 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF569 PF04601.8 EXF80199.1 - 0.032 13.6 0.1 0.077 12.4 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF569) PAP1 PF08601.5 EXF80200.1 - 0.12 12.0 0.0 0.14 11.7 0.0 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 bZIP_1 PF00170.16 EXF80201.1 - 0.00022 21.0 7.1 0.00062 19.6 4.9 1.7 1 0 0 1 1 1 1 bZIP transcription factor TSC22 PF01166.13 EXF80201.1 - 0.17 11.8 1.7 0.27 11.2 0.6 1.8 2 0 0 2 2 2 0 TSC-22/dip/bun family bZIP_2 PF07716.10 EXF80201.1 - 2 8.2 11.1 8.7 6.2 7.3 2.1 1 1 0 1 1 1 0 Basic region leucine zipper Acyltransferase PF01553.16 EXF80202.1 - 3.9e-14 52.2 0.0 5.7e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Pkinase PF00069.20 EXF80203.1 - 1.2e-60 204.8 0.0 2.2e-38 131.8 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EXF80203.1 - 4.8e-28 97.9 0.0 2.2e-20 72.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Response_reg PF00072.19 EXF80203.1 - 3e-14 52.9 0.0 5.9e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.1 EXF80203.1 - 3.2e-06 26.3 0.0 0.00048 19.1 0.0 2.8 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EXF80203.1 - 1e-05 25.3 0.0 0.0037 17.0 0.0 2.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family PAS_9 PF13426.1 EXF80203.1 - 0.047 14.0 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 PAS domain Seadorna_VP7 PF07387.6 EXF80203.1 - 0.061 12.1 0.1 0.11 11.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 EXF80203.1 - 0.11 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS PF00989.19 EXF80203.1 - 0.15 11.8 0.0 0.6 9.9 0.0 2.0 1 1 1 2 2 2 0 PAS fold Sugar_tr PF00083.19 EXF80204.1 - 1.7e-21 76.3 28.0 7.7e-14 51.1 7.3 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Peptidase_S10 PF00450.17 EXF80205.1 - 2.1e-76 257.7 1.1 2.8e-76 257.3 0.8 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Lum_binding PF00677.12 EXF80206.1 - 3.7e-37 126.0 0.0 2.6e-18 65.6 0.0 2.1 2 0 0 2 2 2 2 Lumazine binding domain ERCC4 PF02732.10 EXF80207.1 - 7e-29 100.4 0.1 1.1e-28 99.7 0.1 1.3 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 EXF80207.1 - 0.00011 22.3 0.0 0.00028 21.0 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain HTH_45 PF14947.1 EXF80207.1 - 0.041 13.7 0.1 0.18 11.6 0.1 2.1 1 0 0 1 1 1 0 Winged helix-turn-helix HTH_27 PF13463.1 EXF80207.1 - 0.1 12.9 0.0 0.38 11.1 0.0 2.0 1 0 0 1 1 1 0 Winged helix DNA-binding domain PGM_PMM_I PF02878.11 EXF80208.1 - 1.3e-18 66.8 0.1 7.3e-08 31.9 0.0 3.0 1 1 2 3 3 3 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EXF80208.1 - 3.6e-13 49.7 0.4 1.5e-12 47.7 0.1 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EXF80208.1 - 1.5e-10 40.9 0.6 4.1e-09 36.3 0.1 2.5 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.11 EXF80208.1 - 0.0015 18.5 0.0 0.0041 17.1 0.0 1.8 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III DUF3142 PF11340.3 EXF80209.1 - 0.044 13.4 5.8 0.065 12.8 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3142) Arc PF03869.9 EXF80209.1 - 0.4 10.3 6.5 1.9 8.1 0.2 2.9 2 0 0 2 2 2 0 Arc-like DNA binding domain Filament PF00038.16 EXF80209.1 - 1.2 8.5 81.9 0.012 15.0 7.5 6.1 4 2 1 6 6 6 0 Intermediate filament protein Zn_clus PF00172.13 EXF80210.1 - 3.3e-07 30.1 9.8 5.5e-07 29.3 6.8 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Lipase_3 PF01764.20 EXF80211.1 - 2.9e-19 69.0 0.0 7.4e-19 67.7 0.0 1.7 1 1 1 2 2 2 1 Lipase (class 3) DUF1772 PF08592.6 EXF80213.1 - 2.1e-13 50.1 0.1 3.9e-13 49.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) Fungal_trans PF04082.13 EXF80213.1 - 6.4e-10 38.3 1.7 9.7e-10 37.7 1.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF80213.1 - 1.4e-08 34.5 10.1 2.1e-08 33.9 7.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.8 EXF80214.1 - 8.3e-23 80.8 0.0 1.1e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF80214.1 - 4.4e-14 52.9 1.0 3.7e-13 49.9 0.2 2.0 2 0 0 2 2 2 1 NADH(P)-binding F420_oxidored PF03807.12 EXF80214.1 - 0.0004 20.7 0.6 0.0012 19.2 0.1 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Epimerase PF01370.16 EXF80214.1 - 0.0017 17.8 0.5 0.033 13.6 0.0 2.5 3 1 0 3 3 3 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EXF80214.1 - 0.0018 18.2 0.0 0.0034 17.3 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 EXF80214.1 - 0.0023 16.9 0.4 0.0032 16.5 0.1 1.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EXF80214.1 - 0.0033 17.5 0.5 0.27 11.3 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase KR PF08659.5 EXF80214.1 - 0.011 15.4 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 0 KR domain Semialdhyde_dh PF01118.19 EXF80214.1 - 0.077 13.3 0.5 0.31 11.3 0.1 2.1 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 EXF80214.1 - 0.078 12.9 0.1 0.19 11.7 0.1 1.7 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.16 EXF80214.1 - 0.18 11.6 3.2 0.27 11.0 0.7 2.2 2 0 0 2 2 2 0 ThiF family MFS_1 PF07690.11 EXF80215.1 - 3.6e-34 118.0 34.9 1.2e-33 116.3 24.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily ESSS PF10183.4 EXF80215.1 - 0.0052 17.1 0.1 0.018 15.4 0.1 2.0 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) FAD_binding_3 PF01494.14 EXF80218.1 - 1.1e-17 64.1 0.1 4.6e-09 35.7 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EXF80218.1 - 7.3e-05 22.7 0.0 0.00015 21.6 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EXF80218.1 - 0.0061 16.9 0.0 0.24 11.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF80218.1 - 0.01 14.9 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 EXF80218.1 - 0.011 14.6 0.0 0.78 8.5 0.0 2.4 2 1 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EXF80218.1 - 0.052 13.5 0.0 0.12 12.4 0.0 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF80218.1 - 0.11 11.3 0.0 0.83 8.5 0.0 2.0 2 0 0 2 2 2 0 Lycopene cyclase protein DUF204 PF02659.10 EXF80219.1 - 6 7.0 10.0 26 5.0 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function DUF Acyl-CoA_dh_1 PF00441.19 EXF80220.1 - 6.6e-30 104.1 3.8 9e-30 103.7 2.6 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EXF80220.1 - 1.6e-20 73.7 0.0 3.2e-20 72.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EXF80220.1 - 7.2e-18 63.8 1.1 7.2e-18 63.8 0.7 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain zf-MYND PF01753.13 EXF80221.1 - 6.4e-08 32.3 13.6 1.7e-07 30.9 9.4 1.8 1 0 0 1 1 1 1 MYND finger CIA30 PF08547.7 EXF80222.1 - 0.1 12.4 0.3 6.1 6.6 0.1 2.3 2 0 0 2 2 2 0 Complex I intermediate-associated protein 30 (CIA30) CHAT PF12770.2 EXF80224.1 - 1.7e-35 122.5 0.0 3.1e-35 121.7 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_11 PF13414.1 EXF80224.1 - 1.1e-05 25.0 15.7 0.32 10.6 0.2 6.8 4 1 2 6 6 6 4 TPR repeat TPR_17 PF13431.1 EXF80224.1 - 0.026 14.6 0.6 4.5 7.7 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat IncA PF04156.9 EXF80224.1 - 4.7 6.7 11.0 0.89 9.1 0.1 3.6 5 0 0 5 5 5 0 IncA protein GAF_3 PF13492.1 EXF80225.1 - 0.016 15.2 0.0 0.022 14.8 0.0 1.2 1 0 0 1 1 1 0 GAF domain Dehydratase_hem PF13816.1 EXF80226.1 - 1.7e-111 372.2 0.1 1.9e-111 372.0 0.1 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.1 EXF80226.1 - 3.8e-06 26.9 0.0 0.072 13.1 0.1 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) PRT_C PF08372.5 EXF80227.1 - 0.12 11.8 0.2 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Plant phosphoribosyltransferase C-terminal PfkB PF00294.19 EXF80228.1 - 2.7e-13 49.7 0.0 5.1e-13 48.8 0.0 1.4 1 1 0 1 1 1 1 pfkB family carbohydrate kinase GHMP_kinases_N PF00288.21 EXF80229.1 - 1.8e-11 43.9 0.0 3.8e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EXF80229.1 - 5.2e-05 23.3 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 GHMP kinases C terminal Cerato-platanin PF07249.7 EXF80230.1 - 5.5e-56 187.6 3.2 6.4e-56 187.4 2.2 1.0 1 0 0 1 1 1 1 Cerato-platanin HEAT PF02985.17 EXF80231.1 - 4.8e-15 54.2 2.9 0.00066 19.5 0.1 8.1 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.1 EXF80231.1 - 4e-13 49.4 15.8 0.00022 21.4 0.0 7.6 6 1 2 8 8 8 3 HEAT repeats HEAT_EZ PF13513.1 EXF80231.1 - 1.5e-11 44.4 23.7 2.7e-05 24.4 0.1 10.5 9 1 4 13 13 12 2 HEAT-like repeat IBN_N PF03810.14 EXF80231.1 - 8.8e-06 25.5 3.1 3.1e-05 23.7 0.2 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.3 EXF80231.1 - 9.8e-05 21.8 0.1 0.00097 18.5 0.0 2.7 3 0 0 3 3 3 1 CLASP N terminal Adaptin_N PF01602.15 EXF80231.1 - 0.00012 20.5 0.1 0.11 10.7 0.0 2.9 3 0 0 3 3 3 2 Adaptin N terminal region Cnd1 PF12717.2 EXF80231.1 - 0.00018 21.4 0.1 0.54 10.0 0.0 3.1 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EXF80231.1 - 0.00061 20.1 0.0 0.32 11.3 0.0 3.8 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region UME PF08064.8 EXF80231.1 - 0.0062 16.4 0.0 6.6 6.7 0.0 4.2 4 1 1 5 5 4 1 UME (NUC010) domain Rcd1 PF04078.8 EXF80231.1 - 0.018 13.9 0.0 0.074 11.8 0.0 1.9 2 0 0 2 2 2 0 Cell differentiation family, Rcd1-like Arm PF00514.18 EXF80231.1 - 0.12 12.2 10.4 9.1 6.2 0.1 6.1 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat Alpha-amylase PF00128.19 EXF80234.1 - 1.7e-95 320.0 0.0 2.4e-95 319.5 0.0 1.1 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF4434 PF14488.1 EXF80234.1 - 0.0019 17.9 0.0 0.0038 16.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4434) Glyoxalase_2 PF12681.2 EXF80234.1 - 0.035 14.7 0.0 3.8 8.1 0.0 2.9 2 0 0 2 2 2 0 Glyoxalase-like domain hDGE_amylase PF14701.1 EXF80234.1 - 0.045 12.6 0.0 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Sugar_tr PF00083.19 EXF80235.1 - 1.3e-81 274.4 20.9 1.5e-81 274.2 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF80235.1 - 1.2e-17 63.6 24.3 2.5e-16 59.3 12.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EXF80235.1 - 1.1e-05 24.0 20.9 0.00063 18.2 5.8 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein Folate_carrier PF01770.13 EXF80235.1 - 2.8e-05 22.7 2.8 6e-05 21.7 2.0 1.6 1 1 0 1 1 1 1 Reduced folate carrier Fungal_trans PF04082.13 EXF80236.1 - 0.0013 17.7 0.1 0.002 17.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF80236.1 - 0.013 15.4 8.3 0.021 14.7 5.7 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-U1 PF06220.7 EXF80237.1 - 3.3e-07 29.7 0.2 5.4e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 U1 zinc finger PIR PF00399.14 EXF80238.1 - 0.06 12.7 0.6 0.06 12.7 0.4 4.4 4 0 0 4 4 4 0 Yeast PIR protein repeat NTP_transferase PF00483.18 EXF80241.1 - 1.2e-29 103.4 0.0 1.4e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EXF80241.1 - 1.5e-10 40.0 6.9 5.8e-06 25.5 0.0 3.8 3 1 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EXF80241.1 - 6e-06 26.4 0.0 9.1e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.7 EXF80241.1 - 0.11 10.9 0.1 0.94 7.9 0.0 2.3 2 1 1 3 3 3 0 L-fucokinase Dynamin_N PF00350.18 EXF80242.1 - 1.2e-21 77.2 0.0 1e-20 74.2 0.0 2.4 1 1 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EXF80242.1 - 1.1e-15 57.1 2.9 3.7e-07 29.2 0.3 2.2 2 0 0 2 2 2 2 Dynamin central region GED PF02212.13 EXF80242.1 - 1.3e-05 25.0 1.7 2.7e-05 23.9 0.0 2.4 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EXF80242.1 - 0.0059 16.5 0.0 4 7.4 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase Miro PF08477.8 EXF80242.1 - 0.069 13.6 0.0 0.23 11.9 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein Halo_GVPC PF05465.8 EXF80242.1 - 0.3 11.0 1.8 0.82 9.6 1.2 1.8 1 0 0 1 1 1 0 Halobacterial gas vesicle protein C (GVPC) repeat Sugar_tr PF00083.19 EXF80243.1 - 5.8e-79 265.7 20.9 6.6e-79 265.5 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF80243.1 - 2.1e-26 92.4 19.0 3e-26 91.9 13.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EXF80243.1 - 7.4e-05 21.3 2.5 7.4e-05 21.3 1.7 2.7 2 2 0 2 2 2 1 MFS/sugar transport protein UNC-93 PF05978.11 EXF80243.1 - 0.0024 17.3 3.4 0.0024 17.3 2.4 2.5 3 0 0 3 3 3 1 Ion channel regulatory protein UNC-93 ABC2_membrane PF01061.19 EXF80244.1 - 1.3e-77 259.7 63.1 1.6e-41 141.7 15.6 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EXF80244.1 - 1.1e-35 122.9 0.0 5.9e-17 62.2 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EXF80244.1 - 2.2e-28 97.9 0.1 6.8e-25 86.7 0.0 2.9 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EXF80244.1 - 3.1e-08 33.6 0.2 1.1e-07 31.8 0.1 2.1 2 0 0 2 2 1 1 ABC-transporter extracellular N-terminal AAA_33 PF13671.1 EXF80244.1 - 2.1e-07 30.9 0.0 0.0049 16.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EXF80244.1 - 2.6e-06 28.2 0.0 0.0013 19.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 EXF80244.1 - 2.8e-06 26.8 0.2 0.0061 15.9 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EXF80244.1 - 1.3e-05 25.3 0.0 0.064 13.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EXF80244.1 - 2.8e-05 24.2 0.0 0.089 12.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EXF80244.1 - 8.9e-05 21.9 0.6 0.0056 16.1 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EXF80244.1 - 9.5e-05 21.6 0.0 0.00072 18.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 EXF80244.1 - 0.00017 21.0 1.5 0.0098 15.3 0.2 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 EXF80244.1 - 0.00049 19.7 0.7 0.78 9.3 0.1 2.5 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 EXF80244.1 - 0.001 19.0 0.4 0.19 11.6 0.1 2.7 2 1 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 EXF80244.1 - 0.0019 17.4 0.0 0.68 9.1 0.0 3.3 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain NACHT PF05729.7 EXF80244.1 - 0.0019 17.8 0.9 1.3 8.6 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_18 PF13238.1 EXF80244.1 - 0.0031 17.8 0.1 0.16 12.2 0.0 2.7 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 EXF80244.1 - 0.004 16.2 14.2 0.004 16.2 9.9 3.3 2 1 1 3 3 2 2 ABC-2 family transporter protein AAA_19 PF13245.1 EXF80244.1 - 0.0041 16.8 1.4 2.3 8.0 0.0 3.1 3 0 0 3 3 2 1 Part of AAA domain AAA_28 PF13521.1 EXF80244.1 - 0.0049 16.8 1.3 0.04 13.8 0.0 2.8 3 0 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 EXF80244.1 - 0.0079 15.6 0.1 0.86 9.0 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 EXF80244.1 - 0.082 13.4 0.0 6.4 7.3 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_10 PF12846.2 EXF80244.1 - 0.085 12.2 0.2 4.7 6.5 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain AAA_24 PF13479.1 EXF80244.1 - 0.1 12.1 0.2 11 5.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Hat1_N PF10394.4 EXF80244.1 - 0.13 12.2 1.3 0.21 11.6 0.2 1.8 2 0 0 2 2 1 0 Histone acetyl transferase HAT1 N-terminus AAA PF00004.24 EXF80244.1 - 0.17 12.0 0.8 25 5.0 0.1 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_15 PF13175.1 EXF80244.1 - 0.21 10.5 0.0 1.8 7.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain PduV-EutP PF10662.4 EXF80244.1 - 0.23 10.9 0.7 2.3 7.6 0.1 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.1 EXF80244.1 - 0.52 10.5 0.0 0.52 10.5 0.0 2.3 3 0 0 3 3 1 0 AAA domain p450 PF00067.17 EXF80245.1 - 6.7e-20 71.0 0.0 7.8e-20 70.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DAO PF01266.19 EXF80247.1 - 6.2e-17 61.5 3.1 3.1e-15 55.9 2.2 2.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF80247.1 - 9.4e-15 54.4 0.1 2.6e-14 52.9 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EXF80247.1 - 4.4e-14 52.4 0.5 4.6e-13 49.0 0.0 2.3 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EXF80247.1 - 2.7e-08 33.0 3.0 5e-05 22.3 1.6 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 EXF80247.1 - 1.5e-07 30.2 0.2 0.0013 17.3 0.5 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.2 EXF80247.1 - 2.4e-06 26.9 0.0 0.00091 18.4 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF80247.1 - 1.2e-05 25.2 0.0 0.0001 22.2 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF80247.1 - 7.5e-05 22.8 0.0 0.0028 17.7 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF80247.1 - 0.00046 20.5 1.9 0.12 12.7 0.7 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF80247.1 - 0.0015 17.6 0.1 0.0027 16.8 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 EXF80247.1 - 0.0016 17.5 0.5 0.0028 16.7 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EXF80247.1 - 0.006 15.5 1.9 0.029 13.2 0.2 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein GMC_oxred_N PF00732.14 EXF80247.1 - 0.016 14.3 0.1 1.5 7.8 0.0 2.2 2 0 0 2 2 2 0 GMC oxidoreductase ApbA PF02558.11 EXF80247.1 - 0.029 13.8 0.7 0.059 12.8 0.5 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Trp_halogenase PF04820.9 EXF80247.1 - 0.034 12.7 0.5 5.3 5.5 0.0 2.5 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EXF80247.1 - 0.052 13.3 4.3 0.077 12.7 0.1 2.8 3 0 0 3 3 3 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.18 EXF80247.1 - 0.062 13.0 0.0 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GDI PF00996.13 EXF80247.1 - 0.092 11.0 0.0 5.5 5.1 0.0 2.2 2 0 0 2 2 2 0 GDP dissociation inhibitor XdhC_C PF13478.1 EXF80247.1 - 0.092 13.0 0.1 0.55 10.5 0.0 2.1 2 0 0 2 2 2 0 XdhC Rossmann domain F420_oxidored PF03807.12 EXF80247.1 - 0.13 12.7 0.6 1.8 9.0 0.6 2.3 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EXF80247.1 - 0.13 11.9 0.5 0.21 11.2 0.3 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EXF80247.1 - 0.21 10.4 3.5 0.19 10.5 1.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A SQS_PSY PF00494.14 EXF80248.1 - 8.9e-66 221.9 0.7 1.1e-65 221.5 0.5 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase 4HBT PF03061.17 EXF80249.1 - 1.3e-05 25.2 0.2 2.9e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Thioesterase superfamily GA PF01468.12 EXF80249.1 - 0.35 11.0 4.1 0.6 10.2 2.8 1.3 1 0 0 1 1 1 0 GA module FAD_binding_7 PF03441.9 EXF80250.1 - 2.9e-54 184.1 0.0 4.1e-54 183.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EXF80250.1 - 4.3e-20 72.1 0.0 6.9e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase DUF2953 PF11167.3 EXF80251.1 - 0.028 14.3 0.3 0.048 13.5 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) DEDD_Tnp_IS110 PF01548.12 EXF80251.1 - 0.094 12.3 0.2 0.16 11.6 0.0 1.4 2 0 0 2 2 2 0 Transposase Fungal_trans PF04082.13 EXF80252.1 - 9.6e-08 31.2 0.0 2e-07 30.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF80252.1 - 6.4e-06 25.9 9.8 1.8e-05 24.5 6.8 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mito_fiss_reg PF05308.6 EXF80253.1 - 0.078 12.3 2.3 0.09 12.1 1.6 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Peptidase_M43 PF05572.8 EXF80254.1 - 4.7e-12 45.7 0.0 9.5e-12 44.7 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 EXF80254.1 - 0.0055 17.2 0.2 0.012 16.1 0.1 1.7 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EXF80254.1 - 0.0072 16.3 0.1 0.01 15.8 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EXF80254.1 - 0.0095 15.8 0.0 0.017 15.0 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EXF80254.1 - 0.035 13.6 0.2 0.15 11.5 0.0 1.9 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EXF80254.1 - 0.11 12.2 0.4 0.23 11.1 0.3 1.6 1 1 0 1 1 1 0 Matrixin Acetyltransf_9 PF13527.1 EXF80255.1 - 1.1e-06 28.4 0.0 2.4e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EXF80255.1 - 1.2e-05 25.2 0.0 9.9e-05 22.3 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF80255.1 - 2.4e-05 24.4 0.0 4.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EXF80255.1 - 0.0058 16.7 0.1 0.02 15.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF3571 PF12095.3 EXF80255.1 - 0.12 12.6 0.0 0.33 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3571) Phosphodiest PF01663.17 EXF80257.1 - 3.6e-85 286.4 0.2 4.9e-85 286.0 0.2 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EXF80257.1 - 0.076 12.1 0.0 0.45 9.6 0.0 2.1 2 0 0 2 2 2 0 Sulfatase Dala_Dala_lig_N PF01820.16 EXF80257.1 - 0.12 12.7 0.1 0.76 10.0 0.0 2.4 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus EF-hand_6 PF13405.1 EXF80260.1 - 0.043 13.7 0.2 5.8 7.0 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain GTP_EFTU PF00009.22 EXF80261.1 - 6.7e-57 191.9 0.1 1e-56 191.3 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EXF80261.1 - 7e-36 122.3 0.0 1.6e-35 121.1 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EXF80261.1 - 2.3e-17 62.8 1.0 2.3e-17 62.8 0.7 2.1 3 0 0 3 3 3 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EXF80261.1 - 0.00055 19.5 0.2 0.0016 18.0 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EXF80261.1 - 0.00056 19.8 0.2 0.002 18.0 0.1 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase SLS PF14611.1 EXF80262.1 - 5.1e-27 94.6 3.7 7.5e-27 94.1 2.6 1.3 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator MAGE PF01454.14 EXF80263.1 - 5.5e-37 127.0 0.0 7e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 MAGE family SF3b10 PF07189.6 EXF80264.1 - 5.7e-40 135.0 0.0 6.4e-40 134.8 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) zf-MYND PF01753.13 EXF80265.1 - 0.0028 17.4 2.2 0.0028 17.4 1.5 3.4 3 0 0 3 3 3 1 MYND finger Ecl1 PF12855.2 EXF80265.1 - 0.02 14.1 1.6 0.02 14.1 1.1 2.1 2 0 0 2 2 2 0 Life-span regulatory factor PqqD PF05402.7 EXF80265.1 - 0.077 13.0 1.1 14 5.7 0.0 3.2 4 0 0 4 4 4 0 Coenzyme PQQ synthesis protein D (PqqD) PhaP_Bmeg PF09602.5 EXF80265.1 - 0.17 11.7 7.5 0.1 12.4 2.2 2.5 2 1 1 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) Zn_clus PF00172.13 EXF80266.1 - 0.39 10.6 3.9 0.65 9.9 2.7 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain adh_short PF00106.20 EXF80267.1 - 1.6e-16 60.7 1.4 1.9e-08 34.4 0.0 2.9 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EXF80267.1 - 3.9e-05 23.3 0.8 0.042 13.5 0.5 2.9 2 1 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EXF80267.1 - 0.00025 20.8 0.0 0.00069 19.4 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF3628 PF12300.3 EXF80267.1 - 0.0056 16.7 2.9 0.0056 16.7 2.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3628) Ank_2 PF12796.2 EXF80268.1 - 3.6e-56 187.4 7.8 1.6e-18 66.7 0.1 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EXF80268.1 - 3.6e-51 168.5 9.8 7.1e-09 35.0 0.0 8.3 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.1 EXF80268.1 - 1.7e-47 158.3 10.3 8.1e-13 48.1 0.2 7.1 1 1 5 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF80268.1 - 5.1e-43 140.7 2.2 2.7e-06 27.0 0.0 7.9 8 0 0 8 8 8 7 Ankyrin repeat Ank_4 PF13637.1 EXF80268.1 - 3.4e-41 138.9 2.2 1.4e-13 50.9 0.0 5.8 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Kinesin PF00225.18 EXF80270.1 - 1.3e-105 352.7 3.2 1.3e-105 352.7 2.2 2.0 2 0 0 2 2 2 1 Kinesin motor domain WEMBL PF05701.6 EXF80270.1 - 0.00078 18.0 43.7 0.015 13.7 30.3 2.3 1 1 0 1 1 1 1 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 EXF80270.1 - 0.0083 15.3 10.4 0.72 8.9 0.3 2.7 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Striatin PF08232.7 EXF80270.1 - 0.013 15.7 7.7 0.013 15.7 5.4 4.6 3 2 1 4 4 4 0 Striatin family Nup54 PF13874.1 EXF80270.1 - 0.59 9.7 23.8 0.14 11.7 2.0 3.4 1 1 0 2 2 2 0 Nucleoporin complex subunit 54 Filament PF00038.16 EXF80270.1 - 0.76 9.1 49.7 0.51 9.7 29.8 3.6 2 1 0 2 2 2 0 Intermediate filament protein IncA PF04156.9 EXF80270.1 - 0.84 9.1 47.9 2.5 7.6 14.3 3.4 1 1 1 2 2 2 0 IncA protein DUF3584 PF12128.3 EXF80270.1 - 1.1 6.4 39.5 0.21 8.9 23.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF1664 PF07889.7 EXF80270.1 - 1.7 8.4 18.1 0.88 9.3 2.3 4.1 2 1 1 4 4 4 0 Protein of unknown function (DUF1664) DivIC PF04977.10 EXF80270.1 - 5.5 6.5 21.0 0.42 10.1 0.1 4.7 1 1 2 4 4 4 0 Septum formation initiator DUF4200 PF13863.1 EXF80270.1 - 9.8 6.1 46.0 0.12 12.3 7.5 3.7 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) Acyltransferase PF01553.16 EXF80271.1 - 1.6e-05 24.3 0.0 2.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase ILVD_EDD PF00920.16 EXF80272.1 - 6.4e-209 694.6 0.2 7.5e-209 694.4 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family CLP_protease PF00574.18 EXF80273.1 - 2e-69 232.9 0.2 2.7e-69 232.5 0.1 1.1 1 0 0 1 1 1 1 Clp protease FMO-like PF00743.14 EXF80273.1 - 0.13 10.4 0.2 0.18 9.9 0.2 1.2 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like Dynamin_N PF00350.18 EXF80275.1 - 2.1e-12 47.1 0.3 1.1e-11 44.8 0.0 2.3 2 0 0 2 2 2 1 Dynamin family KAP_NTPase PF07693.9 EXF80275.1 - 7.1e-05 21.9 0.2 0.023 13.7 0.0 3.0 3 0 0 3 3 3 2 KAP family P-loop domain MMR_HSR1 PF01926.18 EXF80275.1 - 0.00018 21.4 0.0 0.0071 16.2 0.0 2.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Borrelia_lipo_2 PF06238.6 EXF80275.1 - 0.0012 18.9 0.1 0.01 15.8 0.0 2.6 3 0 0 3 3 3 1 Borrelia burgdorferi BBR25 lipoprotein ABC_tran PF00005.22 EXF80275.1 - 0.013 15.7 0.2 0.057 13.7 0.0 2.2 2 0 0 2 2 2 0 ABC transporter DUF258 PF03193.11 EXF80275.1 - 0.022 13.9 0.0 0.058 12.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Clr5 PF14420.1 EXF80276.1 - 5.4e-21 74.2 0.4 1.1e-20 73.2 0.3 1.6 1 0 0 1 1 1 1 Clr5 domain Macoilin PF09726.4 EXF80276.1 - 3.5 5.7 10.0 6 5.0 6.9 1.3 1 0 0 1 1 1 0 Transmembrane protein DUF4407 PF14362.1 EXF80276.1 - 4 6.3 5.0 6.5 5.6 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MFS_1 PF07690.11 EXF80277.1 - 2.9e-29 101.8 20.4 2.9e-29 101.8 14.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily UPF0546 PF10639.4 EXF80277.1 - 0.13 12.0 2.1 3.8 7.3 0.4 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 Gly-zipper_Omp PF13488.1 EXF80277.1 - 0.51 10.0 4.1 10 5.8 0.5 2.8 2 0 0 2 2 2 0 Glycine zipper DUF3099 PF11298.3 EXF80277.1 - 3.3 7.5 4.7 1.3 8.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3099) MBOAT PF03062.14 EXF80278.1 - 1.2e-30 106.7 19.9 3.1e-30 105.3 13.8 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF3433 PF11915.3 EXF80279.1 - 1.5e-16 60.3 8.8 9.6e-16 57.7 0.4 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) COX2_TM PF02790.10 EXF80279.1 - 9.3 6.2 16.1 0.62 10.0 2.3 3.4 3 0 0 3 3 3 0 Cytochrome C oxidase subunit II, transmembrane domain FAR1 PF03101.10 EXF80280.1 - 4.4e-08 33.5 0.3 4.4e-08 33.5 0.2 1.5 2 0 0 2 2 2 1 FAR1 DNA-binding domain DnaJ PF00226.26 EXF80281.1 - 2.5e-22 78.3 1.2 9.3e-22 76.5 0.8 2.1 1 0 0 1 1 1 1 DnaJ domain Metallophos PF00149.23 EXF80283.1 - 1.2e-11 44.4 0.3 1.3e-07 31.2 0.0 2.3 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EXF80283.1 - 1.6e-07 31.2 0.0 3.8e-07 30.0 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF3176 PF11374.3 EXF80285.1 - 4.8e-33 113.3 3.5 9.9e-33 112.3 2.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF3290 PF11694.3 EXF80285.1 - 0.19 11.4 1.2 0.46 10.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) Ank_2 PF12796.2 EXF80288.1 - 1.5e-07 31.6 0.2 2.3e-05 24.6 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EXF80288.1 - 1e-05 25.0 0.8 0.05 13.4 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EXF80288.1 - 7.2e-05 22.9 0.1 0.19 12.0 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EXF80288.1 - 0.00013 22.3 0.5 0.089 13.3 0.0 3.3 2 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF80288.1 - 0.013 15.6 1.6 4.6 7.7 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat Methyltransf_31 PF13847.1 EXF80288.1 - 0.089 12.3 0.1 2 8.0 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain DUF3431 PF11913.3 EXF80290.1 - 2.7e-14 53.1 0.1 1.2e-13 51.0 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3431) DUF3443 PF11925.3 EXF80291.1 - 0.093 11.3 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3443) MFS_1 PF07690.11 EXF80292.1 - 5.1e-36 124.1 34.8 6.1e-36 123.8 24.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Ytp1 PF10355.4 EXF80293.1 - 1.6e-81 273.5 14.6 1.6e-81 273.5 10.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (Ytp1) DUF2427 PF10348.4 EXF80293.1 - 2.4e-32 110.6 4.7 2.4e-32 110.6 3.3 2.3 3 0 0 3 3 3 1 Domain of unknown function (DUF2427) FliG_C PF01706.11 EXF80294.1 - 0.13 12.2 3.2 0.15 12.0 1.9 1.4 1 1 0 1 1 1 0 FliG C-terminal domain Amidohydro_1 PF01979.15 EXF80296.1 - 1e-25 91.1 0.4 1.4e-25 90.7 0.3 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EXF80296.1 - 1.3e-12 48.3 5.3 4.7e-07 30.1 0.2 2.8 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_3 PF07969.6 EXF80296.1 - 3e-06 26.7 1.8 4.6e-05 22.8 0.3 2.4 2 1 0 2 2 2 1 Amidohydrolase family Amidohydro_5 PF13594.1 EXF80296.1 - 8.8e-06 25.4 0.2 0.00055 19.7 0.0 2.8 3 0 0 3 3 3 1 Amidohydrolase ketoacyl-synt PF00109.21 EXF80297.1 - 9.9e-68 228.3 0.0 1.7e-67 227.5 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EXF80297.1 - 2.3e-57 193.5 1.8 3.3e-57 193.0 0.1 2.2 2 0 0 2 2 2 1 KR domain Acyl_transf_1 PF00698.16 EXF80297.1 - 5e-47 160.7 0.0 8.3e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain adh_short PF00106.20 EXF80297.1 - 4.5e-44 150.3 6.2 1.7e-43 148.4 0.0 3.5 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EXF80297.1 - 6.9e-38 129.1 0.0 1.8e-37 127.7 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EXF80297.1 - 5e-36 124.3 0.1 9.7e-36 123.4 0.1 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.21 EXF80297.1 - 4.2e-17 61.9 0.3 1.2e-16 60.4 0.2 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EXF80297.1 - 2.5e-15 56.7 0.0 7.4e-15 55.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF80297.1 - 2.7e-09 36.9 0.0 7.5e-09 35.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF80297.1 - 1.5e-08 35.1 0.7 2.3e-07 31.3 0.0 3.4 5 0 0 5 5 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF80297.1 - 8.4e-08 32.6 0.0 2.4e-07 31.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF80297.1 - 2.6e-07 30.3 0.0 6.2e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EXF80297.1 - 8.2e-05 21.7 0.0 0.00016 20.7 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EXF80297.1 - 0.00065 19.3 0.0 0.002 17.7 0.0 1.9 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_zinc_N_2 PF13602.1 EXF80297.1 - 0.0023 18.8 0.1 0.053 14.4 0.0 3.0 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF80297.1 - 0.0093 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Ubie_methyltran PF01209.13 EXF80297.1 - 0.054 12.5 0.0 0.45 9.5 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family PP-binding PF00550.20 EXF80297.1 - 0.058 13.6 0.1 0.25 11.6 0.0 2.2 2 0 0 2 2 1 0 Phosphopantetheine attachment site NodS PF05401.6 EXF80297.1 - 0.2 11.0 0.0 0.42 9.9 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) CheR PF01739.13 EXF80297.1 - 0.27 10.5 0.0 0.49 9.6 0.0 1.4 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_11 PF08241.7 EXF80298.1 - 7.2e-10 39.2 0.0 1.6e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF80298.1 - 4e-09 36.8 0.0 1.1e-08 35.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF80298.1 - 5.4e-09 35.9 0.0 9e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF80298.1 - 1.1e-06 29.2 0.0 2.6e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF80298.1 - 1.1e-05 25.0 0.0 5.6e-05 22.7 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF80298.1 - 2.6e-05 24.4 0.0 4.8e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF80298.1 - 0.00063 19.7 0.2 0.0014 18.6 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.11 EXF80298.1 - 0.049 12.4 0.0 0.067 12.0 0.0 1.1 1 0 0 1 1 1 0 mRNA capping enzyme DUF4267 PF14087.1 EXF80299.1 - 2e-10 40.2 0.2 2.3e-10 40.0 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) p450 PF00067.17 EXF80300.1 - 1.6e-18 66.4 0.0 4.4e-16 58.4 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.17 EXF80301.1 - 1e-50 172.6 0.0 1.4e-50 172.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M28 PF04389.12 EXF80302.1 - 1.2e-33 116.3 0.1 2.9e-33 115.1 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 EXF80302.1 - 5.5e-06 26.0 0.0 9.6e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M42 PF05343.9 EXF80302.1 - 4e-05 22.5 0.0 9e-05 21.3 0.0 1.6 1 1 0 1 1 1 1 M42 glutamyl aminopeptidase Nicastrin PF05450.10 EXF80302.1 - 0.03 13.5 0.0 0.053 12.7 0.0 1.4 1 0 0 1 1 1 0 Nicastrin Ammonium_transp PF00909.16 EXF80303.1 - 1.5e-118 395.7 31.2 1.7e-118 395.5 21.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Methyltransf_24 PF13578.1 EXF80304.1 - 3e-10 40.8 0.0 6.5e-10 39.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.12 EXF80304.1 - 1.9e-07 30.3 0.0 2.5e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase CmcI PF04989.7 EXF80304.1 - 0.0017 17.7 0.0 0.0051 16.1 0.0 1.7 2 0 0 2 2 2 1 Cephalosporin hydroxylase Methyltransf_18 PF12847.2 EXF80304.1 - 0.0029 18.1 0.0 0.011 16.3 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF80304.1 - 0.0051 16.8 0.0 0.009 16.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TFR_dimer PF04253.10 EXF80305.1 - 7.5e-21 73.9 0.0 1.2e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EXF80305.1 - 2.3e-15 56.8 0.0 4.3e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EXF80305.1 - 9.6e-06 25.2 0.0 2.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EXF80305.1 - 0.0014 18.1 0.0 0.0024 17.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M20 PF01546.23 EXF80306.1 - 1.8e-25 89.5 0.1 2.4e-25 89.1 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EXF80306.1 - 7.1e-06 25.7 0.0 1.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EXF80306.1 - 0.034 13.8 0.0 0.21 11.3 0.0 2.2 3 0 0 3 3 3 0 Peptidase family M28 MFS_1 PF07690.11 EXF80307.1 - 2.3e-26 92.3 40.8 2.3e-26 92.3 28.3 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3624 PF12292.3 EXF80307.1 - 0.00017 21.8 1.6 0.047 14.0 0.2 3.1 2 0 0 2 2 2 2 Protein of unknown function (DUF3624) Adeno_E3_14_5 PF04834.7 EXF80307.1 - 0.11 12.9 0.9 0.61 10.5 0.0 2.7 4 0 0 4 4 4 0 Early E3 14.5 kDa protein Syndecan PF01034.15 EXF80307.1 - 0.55 9.9 2.4 0.91 9.2 0.1 2.4 2 0 0 2 2 2 0 Syndecan domain F-box PF00646.28 EXF80308.1 - 0.001 18.6 0.0 0.0062 16.1 0.0 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EXF80308.1 - 0.0027 17.3 0.0 0.012 15.3 0.0 2.1 1 0 0 1 1 1 1 F-box-like Peptidase_M14 PF00246.19 EXF80309.1 - 4.7e-39 134.6 0.9 6.4e-39 134.2 0.6 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase ThuA PF06283.6 EXF80310.1 - 2.7e-56 190.7 0.1 5.4e-56 189.7 0.1 1.4 1 1 0 1 1 1 1 Trehalose utilisation PLDc_2 PF13091.1 EXF80311.1 - 1.2e-15 57.4 0.0 1.5e-10 40.9 0.0 2.5 2 1 0 2 2 2 2 PLD-like domain Regulator_TrmB PF11495.3 EXF80311.1 - 0.069 12.1 0.1 10 5.0 0.0 2.4 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB BAR PF03114.13 EXF80312.1 - 4.2e-47 160.5 3.5 5.2e-47 160.2 2.4 1.1 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 EXF80312.1 - 3.4e-07 29.4 0.8 4.3e-07 29.1 0.5 1.1 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Ebp2 PF05890.7 EXF80312.1 - 0.0015 17.9 1.0 0.0026 17.0 0.7 1.3 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 DUF883 PF05957.8 EXF80312.1 - 3.2 8.2 6.7 15 6.0 4.7 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) Cyclin_N PF00134.18 EXF80313.1 - 0.0006 19.3 0.1 0.0013 18.2 0.0 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Fasciclin PF02469.17 EXF80314.1 - 5e-44 149.3 2.9 1.9e-23 82.8 0.4 2.2 2 0 0 2 2 2 2 Fasciclin domain EPO_TPO PF00758.13 EXF80314.1 - 1.6 8.3 5.6 3.8 7.1 3.9 1.6 1 0 0 1 1 1 0 Erythropoietin/thrombopoietin MS_channel PF00924.13 EXF80315.1 - 1.6e-16 60.2 0.2 1.6e-16 60.2 0.2 1.7 2 0 0 2 2 2 1 Mechanosensitive ion channel EF-hand_7 PF13499.1 EXF80315.1 - 0.059 13.5 0.0 3.9 7.6 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain pair DUF3753 PF12575.3 EXF80315.1 - 4.6 7.0 6.9 0.7 9.7 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) AA_permease_2 PF13520.1 EXF80316.1 - 3.3e-81 272.9 26.0 4.5e-81 272.5 18.0 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF80316.1 - 4.8e-13 48.2 22.4 7.3e-13 47.6 15.5 1.2 1 0 0 1 1 1 1 Amino acid permease Aa_trans PF01490.13 EXF80316.1 - 0.17 10.3 14.5 1.1 7.7 9.9 2.7 1 1 0 1 1 1 0 Transmembrane amino acid transporter protein DUF4234 PF14018.1 EXF80316.1 - 0.62 9.8 5.9 3.7 7.3 0.1 3.4 3 1 0 3 3 3 0 Domain of unknown function (DUF4234) Glyco_hydro_3 PF00933.16 EXF80318.1 - 1.7e-83 280.0 0.0 2.4e-83 279.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF80318.1 - 7.7e-40 136.8 1.4 1.6e-39 135.7 0.0 2.2 3 0 0 3 3 3 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF80318.1 - 2e-23 82.1 0.1 3.4e-23 81.3 0.1 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Fungal_trans PF04082.13 EXF80319.1 - 4.6e-17 61.7 0.2 7.4e-17 61.0 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain RNA_pol_Rpb1_1 PF04997.7 EXF80320.1 - 1.1e-110 370.1 0.0 2.2e-110 369.1 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EXF80320.1 - 2.3e-102 341.9 0.0 4e-102 341.2 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EXF80320.1 - 8.2e-70 234.0 0.0 1.8e-69 232.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EXF80320.1 - 2.3e-54 184.0 4.7 4.4e-54 183.0 3.2 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EXF80320.1 - 3.3e-44 150.4 0.0 7.2e-44 149.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EXF80320.1 - 1.4e-43 147.8 5.7 1.4e-43 147.8 3.9 2.0 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EXF80320.1 - 3.8e-37 126.3 0.1 8.4e-37 125.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 WD40 PF00400.27 EXF80321.1 - 1.6e-14 53.1 9.8 0.00046 19.9 0.4 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EXF80321.1 - 8e-06 25.6 0.2 0.012 15.3 0.0 3.1 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Clathrin_propel PF01394.15 EXF80321.1 - 0.072 13.4 0.7 22 5.6 0.0 3.3 4 0 0 4 4 4 0 Clathrin propeller repeat Thg1C PF14413.1 EXF80322.1 - 3.2e-50 168.8 0.4 4.4e-50 168.4 0.3 1.2 1 0 0 1 1 1 1 Thg1 C terminal domain Thg1 PF04446.7 EXF80322.1 - 8.3e-47 158.2 0.0 1.2e-46 157.6 0.0 1.3 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Asp-B-Hydro_N PF05279.6 EXF80323.1 - 0.58 9.9 15.2 0.79 9.5 10.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SAGA-Tad1 PF12767.2 EXF80323.1 - 2.7 7.6 6.4 4 7.0 4.5 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF4407 PF14362.1 EXF80323.1 - 3.4 6.5 12.0 4.8 6.0 8.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HMGL-like PF00682.14 EXF80324.1 - 4.7e-71 239.2 0.5 7.8e-71 238.4 0.4 1.4 1 0 0 1 1 1 1 HMGL-like Bromodomain PF00439.20 EXF80325.1 - 2.4e-29 101.0 0.9 6.4e-14 51.6 0.0 2.5 2 0 0 2 2 2 2 Bromodomain RNA_pol_3_Rpc31 PF11705.3 EXF80325.1 - 0.0069 16.3 13.5 0.0069 16.3 9.3 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 Nop14 PF04147.7 EXF80325.1 - 0.014 13.3 15.2 0.021 12.7 10.6 1.1 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EXF80325.1 - 0.48 8.8 21.3 0.0062 15.1 9.3 1.8 2 0 0 2 2 2 0 Daxx Family CDC45 PF02724.9 EXF80325.1 - 2 6.3 14.6 3.4 5.5 10.1 1.2 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.6 EXF80325.1 - 3.5 7.0 17.6 0.68 9.4 9.5 1.9 2 0 0 2 2 2 0 PPP4R2 CKS PF01111.14 EXF80326.1 - 5.1e-36 122.3 0.8 6.4e-36 122.0 0.6 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit ERO1 PF04137.10 EXF80327.1 - 1.2e-136 455.4 0.0 1.5e-136 455.1 0.0 1.1 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) Glutaredoxin PF00462.19 EXF80327.1 - 0.033 14.1 0.0 0.088 12.8 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin HVSL PF09749.4 EXF80328.1 - 7.7e-61 205.1 0.0 9.8e-61 204.8 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised conserved protein Pal1 PF08316.6 EXF80329.1 - 9.4e-09 35.8 1.7 2.1e-08 34.7 0.0 2.3 2 1 1 3 3 3 1 Pal1 cell morphology protein CPSF_A PF03178.10 EXF80330.1 - 6.8e-76 255.4 0.0 4.7e-75 252.6 0.0 2.2 2 0 0 2 2 2 1 CPSF A subunit region LMBR1 PF04791.11 EXF80331.1 - 8.3e-18 64.2 13.5 2.1e-17 62.9 3.2 2.4 1 1 1 2 2 2 2 LMBR1-like membrane protein DUF1980 PF09323.5 EXF80331.1 - 2.1 8.0 5.9 4.5 6.9 0.8 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) zf-B_box PF00643.19 EXF80332.1 - 0.4 10.6 3.3 0.61 10.0 2.3 1.3 1 0 0 1 1 1 0 B-box zinc finger zf-C3HC4_2 PF13923.1 EXF80332.1 - 3.9 7.5 7.1 6.4 6.9 4.9 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PAT1 PF09770.4 EXF80332.1 - 4.5 5.3 12.2 5.5 5.0 8.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UDG PF03167.14 EXF80334.1 - 1.1e-19 70.3 0.1 6.8e-19 67.8 0.0 2.0 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily POR_N PF01855.14 EXF80334.1 - 0.11 11.9 0.2 0.21 11.0 0.1 1.3 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg Glyco_hydro_47 PF01532.15 EXF80335.1 - 3.3e-135 451.2 0.0 4.1e-135 450.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 MFS_1 PF07690.11 EXF80336.1 - 1.1e-16 60.4 41.4 1.1e-16 60.4 28.7 3.0 1 1 2 3 3 3 2 Major Facilitator Superfamily PQ-loop PF04193.9 EXF80337.1 - 2.5e-41 139.0 8.3 2.3e-20 71.8 0.5 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 EXF80337.1 - 0.13 12.1 0.3 0.13 12.1 0.2 2.3 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Isochorismatase PF00857.15 EXF80338.1 - 4.3e-27 95.1 0.0 6.8e-27 94.5 0.0 1.3 1 1 0 1 1 1 1 Isochorismatase family DUF1009 PF06230.6 EXF80338.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1009) PHD PF00628.24 EXF80339.1 - 0.013 15.1 9.3 0.022 14.4 6.5 1.4 1 0 0 1 1 1 0 PHD-finger Microtub_assoc PF07989.6 EXF80339.1 - 0.8 9.5 4.4 1.6 8.5 0.8 2.4 2 0 0 2 2 2 0 Microtubule associated PHD_2 PF13831.1 EXF80339.1 - 1 8.7 10.9 0.68 9.2 0.1 2.7 3 0 0 3 3 3 0 PHD-finger zf-HC5HC2H PF13771.1 EXF80339.1 - 1.4 9.1 8.7 3.2 7.9 6.0 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain C1_1 PF00130.17 EXF80339.1 - 7.6 6.3 14.3 0.54 10.0 3.4 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) MFS_1 PF07690.11 EXF80340.1 - 3.6e-26 91.7 50.6 1.8e-20 72.9 21.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NUDIX PF00293.23 EXF80341.1 - 2.4e-16 59.5 0.0 5.3e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain NUDIX-like PF09296.6 EXF80341.1 - 5.1e-15 55.6 0.0 2.3e-14 53.5 0.0 2.1 3 0 0 3 3 3 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.6 EXF80341.1 - 5.1e-05 22.6 0.4 9.8e-05 21.7 0.3 1.4 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Arf PF00025.16 EXF80342.1 - 1.4e-40 138.3 0.0 2.3e-40 137.6 0.0 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EXF80342.1 - 2e-13 49.7 0.0 5.8e-10 38.4 0.0 2.0 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EXF80342.1 - 8.6e-11 41.4 0.0 3.8e-10 39.3 0.0 1.8 1 1 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EXF80342.1 - 7.4e-08 31.8 0.0 8.5e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EXF80342.1 - 2.1e-07 30.3 0.0 8.2e-07 28.4 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EXF80342.1 - 6.5e-06 25.6 0.1 2e-05 24.0 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EXF80342.1 - 1.6e-05 25.3 0.0 0.00017 22.0 0.0 2.2 1 1 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EXF80342.1 - 0.0035 17.3 0.0 0.0054 16.6 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase NACHT PF05729.7 EXF80342.1 - 0.079 12.6 0.0 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 NACHT domain RNase_PH PF01138.16 EXF80343.1 - 2.9e-23 82.6 0.0 4.8e-23 81.9 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EXF80343.1 - 1.7e-06 27.8 0.0 2.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Cwf_Cwc_15 PF04889.7 EXF80344.1 - 1.6e-84 283.4 18.8 1.8e-84 283.3 13.0 1.0 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein GEMIN8 PF15348.1 EXF80344.1 - 0.0079 16.2 8.8 0.0098 15.9 6.1 1.2 1 0 0 1 1 1 1 Gemini of Cajal bodies-associated protein 8 DUF2890 PF11081.3 EXF80344.1 - 0.032 14.3 14.2 0.058 13.4 9.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) DUF1509 PF07420.6 EXF80344.1 - 0.033 13.4 8.3 0.039 13.2 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) SDA1 PF05285.7 EXF80344.1 - 0.15 11.3 24.2 0.18 11.0 16.7 1.2 1 0 0 1 1 1 0 SDA1 CDC27 PF09507.5 EXF80344.1 - 0.28 10.3 15.6 0.34 10.0 10.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop53 PF07767.6 EXF80344.1 - 0.36 9.7 21.4 0.52 9.2 14.9 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) SGT1 PF07093.6 EXF80344.1 - 0.59 8.4 14.7 0.62 8.3 10.2 1.1 1 0 0 1 1 1 0 SGT1 protein DDHD PF02862.12 EXF80344.1 - 0.68 9.6 3.4 0.84 9.3 2.4 1.3 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.9 EXF80344.1 - 0.78 7.6 22.1 0.95 7.4 15.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EXF80344.1 - 0.94 7.3 27.2 1 7.1 18.8 1.2 1 0 0 1 1 1 0 Nop14-like family FLO_LFY PF01698.11 EXF80344.1 - 1.5 7.5 11.3 2.2 7.0 7.8 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein SAPS PF04499.10 EXF80344.1 - 1.7 7.1 6.9 2.1 6.9 4.8 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Daxx PF03344.10 EXF80344.1 - 4.8 5.5 19.9 5.9 5.2 13.8 1.3 1 0 0 1 1 1 0 Daxx Family adh_short PF00106.20 EXF80345.1 - 3.3e-23 82.4 8.3 1e-22 80.8 5.8 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF80345.1 - 8e-15 54.9 3.1 1.1e-14 54.5 2.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF80345.1 - 5.1e-09 35.9 0.1 6.8e-09 35.5 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EXF80345.1 - 5.4e-07 28.9 1.0 7.1e-07 28.5 0.6 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EXF80345.1 - 3e-05 24.0 1.4 6.6e-05 22.9 0.9 1.8 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EXF80345.1 - 0.001 18.0 0.2 0.0016 17.3 0.2 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EXF80345.1 - 0.03 14.4 0.5 0.064 13.3 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 EXF80345.1 - 0.032 14.5 0.1 0.086 13.1 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain UPF0444 PF15475.1 EXF80345.1 - 0.7 9.9 3.8 0.37 10.8 0.5 2.0 2 0 0 2 2 2 0 Transmembrane protein C12orf23, UPF0444 Ras PF00071.17 EXF80348.1 - 6e-58 194.8 0.0 7.3e-58 194.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EXF80348.1 - 2.3e-20 73.2 0.0 3.8e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EXF80348.1 - 1.8e-14 53.3 0.0 3.3e-14 52.5 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EXF80348.1 - 1.4e-06 27.5 0.0 1.8e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EXF80348.1 - 1.6e-06 27.7 0.0 3.9e-06 26.4 0.0 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EXF80348.1 - 0.00013 21.8 0.0 0.00023 21.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EXF80348.1 - 0.0085 16.0 0.0 0.021 14.8 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EXF80348.1 - 0.062 13.4 0.0 0.22 11.6 0.0 1.9 2 1 0 2 2 2 0 AAA domain AIF-MLS PF14962.1 EXF80348.1 - 0.11 12.2 1.6 0.17 11.5 1.1 1.4 1 0 0 1 1 1 0 Mitochondria Localisation Sequence Kri1 PF05178.7 EXF80349.1 - 9e-26 90.0 24.4 9e-26 90.0 16.9 5.4 6 0 0 6 6 6 1 KRI1-like family Kri1_C PF12936.2 EXF80349.1 - 5.4e-25 87.1 0.1 5.4e-25 87.1 0.1 4.3 6 0 0 6 6 6 1 KRI1-like family C-terminal fn3_3 PF14686.1 EXF80350.1 - 1.9e-10 40.7 0.3 6.8e-10 38.9 0.2 1.9 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CBM-like PF14683.1 EXF80350.1 - 7.6e-09 35.4 0.0 1.4e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III CarboxypepD_reg PF13620.1 EXF80350.1 - 0.048 13.7 0.1 0.17 11.9 0.1 1.9 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain Glyco_hydro_76 PF03663.9 EXF80351.1 - 2.5e-43 148.9 18.8 3.9e-42 144.9 13.1 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EXF80351.1 - 4.9e-05 22.5 1.6 0.11 11.4 0.8 2.7 1 1 1 2 2 2 2 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.8 EXF80351.1 - 0.022 14.0 0.0 0.053 12.7 0.0 1.7 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus Zip PF02535.17 EXF80352.1 - 1.6e-28 99.6 12.9 2.6e-27 95.6 7.6 2.6 1 1 1 2 2 2 1 ZIP Zinc transporter WD40 PF00400.27 EXF80353.1 - 1.1e-50 167.8 16.7 1.6e-10 40.4 0.3 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EXF80353.1 - 1.1e-12 47.4 0.9 2.2e-12 46.5 0.6 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EXF80353.1 - 4.9e-09 34.8 10.6 0.026 12.6 0.1 6.0 1 1 5 6 6 6 5 Nucleoporin Nup120/160 F-box PF00646.28 EXF80353.1 - 4.2e-06 26.2 2.4 8.6e-06 25.2 1.7 1.6 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.1 EXF80353.1 - 0.00051 20.2 0.3 8.2 6.8 0.0 5.1 5 0 0 5 5 5 1 PQQ-like domain F-box-like_2 PF13013.1 EXF80353.1 - 0.099 12.3 0.2 0.41 10.3 0.0 2.1 2 0 0 2 2 2 0 F-box-like domain E1_dh PF00676.15 EXF80354.1 - 7.3e-111 369.6 0.4 9.1e-111 369.3 0.3 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EXF80354.1 - 0.002 17.1 0.2 0.0039 16.1 0.0 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase DNA_ligase_A_M PF01068.16 EXF80355.1 - 1.5e-56 191.0 0.8 2.3e-45 154.4 0.1 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EXF80355.1 - 2.7e-51 173.8 0.0 5.4e-51 172.9 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EXF80355.1 - 9.9e-28 96.4 0.0 5.7e-27 93.9 0.0 2.4 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region Abhydrolase_6 PF12697.2 EXF80356.1 - 2.8e-06 27.3 0.0 5.9e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 EXF80356.1 - 0.016 14.1 0.0 0.042 12.8 0.0 1.6 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.15 EXF80356.1 - 0.018 14.5 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.8 EXF80356.1 - 0.15 11.6 0.0 0.26 10.8 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein His_Phos_2 PF00328.17 EXF80358.1 - 5.5e-24 85.1 0.0 1.6e-22 80.3 0.0 2.2 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Collagen PF01391.13 EXF80359.1 - 7.1 6.2 18.6 2.6 7.6 4.6 4.6 4 1 0 4 4 4 0 Collagen triple helix repeat (20 copies) PI-PLC-X PF00388.14 EXF80360.1 - 2.9e-61 205.1 0.0 4.3e-61 204.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EXF80360.1 - 1.2e-36 125.2 0.0 2.2e-36 124.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain EF-hand_like PF09279.6 EXF80360.1 - 0.0067 16.4 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like CorA PF01544.13 EXF80361.1 - 5.5e-05 22.3 0.0 0.00012 21.2 0.0 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein COX16 PF14138.1 EXF80361.1 - 0.026 14.6 0.0 0.73 10.0 0.0 3.0 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein COX16 Lectin_leg-like PF03388.8 EXF80362.1 - 3e-65 219.5 0.0 3.9e-65 219.1 0.0 1.1 1 0 0 1 1 1 1 Legume-like lectin family Lectin_legB PF00139.14 EXF80362.1 - 0.002 17.5 0.0 0.014 14.7 0.0 2.0 1 1 0 1 1 1 1 Legume lectin domain ATG27 PF09451.5 EXF80362.1 - 0.031 13.4 0.2 0.047 12.9 0.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 zf-Tim10_DDP PF02953.10 EXF80363.1 - 6.5e-23 79.7 2.2 7.8e-23 79.5 1.5 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger PMEI PF04043.10 EXF80363.1 - 0.035 13.9 0.1 0.042 13.7 0.1 1.1 1 0 0 1 1 1 0 Plant invertase/pectin methylesterase inhibitor DUF3399 PF11879.3 EXF80363.1 - 0.27 11.4 1.9 0.75 10.0 1.3 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3399) DUF2040 PF09745.4 EXF80364.1 - 2.1e-39 134.2 24.2 2.1e-39 134.2 16.8 3.5 2 1 1 3 3 3 2 Coiled-coil domain-containing protein 55 (DUF2040) LMBR1 PF04791.11 EXF80365.1 - 2.7e-23 82.3 6.3 5.5e-23 81.2 4.3 1.3 1 1 0 1 1 1 1 LMBR1-like membrane protein CAF1 PF04857.15 EXF80366.1 - 2.1e-69 233.7 0.0 2.7e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease NDUF_B12 PF08122.7 EXF80367.1 - 4.5e-15 55.1 0.6 6.8e-15 54.5 0.4 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Gp_dh_C PF02800.15 EXF80368.1 - 0.11 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Spc7 PF08317.6 EXF80368.1 - 0.25 9.9 8.3 0.16 10.5 4.6 1.5 2 0 0 2 2 2 0 Spc7 kinetochore protein Fib_alpha PF08702.5 EXF80368.1 - 0.37 10.9 5.9 0.33 11.0 2.8 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.6 EXF80368.1 - 1.1 9.2 3.5 10 6.1 1.0 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) IncA PF04156.9 EXF80368.1 - 1.1 8.7 9.8 0.54 9.8 5.2 1.6 2 0 0 2 2 2 0 IncA protein Mnd1 PF03962.10 EXF80368.1 - 4.8 6.8 12.8 1.9 8.1 7.1 1.6 2 0 0 2 2 2 0 Mnd1 family Macoilin PF09726.4 EXF80368.1 - 5.7 5.0 14.8 0.049 11.9 3.9 1.7 1 1 1 2 2 2 0 Transmembrane protein DUF2570 PF10828.3 EXF80368.1 - 8.2 6.0 10.6 3 7.4 5.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) eIF-6 PF01912.13 EXF80369.1 - 1e-83 279.3 0.4 1.4e-83 278.8 0.3 1.2 1 0 0 1 1 1 1 eIF-6 family NRDE-2 PF08424.5 EXF80370.1 - 2e-81 273.4 0.1 2e-81 273.4 0.0 3.2 4 0 0 4 4 4 2 NRDE-2, necessary for RNA interference TPR_17 PF13431.1 EXF80370.1 - 0.016 15.3 1.4 2.9 8.3 0.3 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.1 EXF80370.1 - 0.063 13.9 12.0 1e+02 3.9 0.0 6.8 6 1 1 7 7 7 0 Tetratricopeptide repeat SelP_N PF04592.9 EXF80370.1 - 3.3 7.0 5.9 7.6 5.8 4.1 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Voltage_CLC PF00654.15 EXF80371.1 - 3.4e-93 312.4 24.2 3.4e-93 312.4 16.8 2.1 2 1 0 2 2 2 1 Voltage gated chloride channel TAT_signal PF10518.4 EXF80371.1 - 0.013 15.4 3.4 0.013 15.4 2.4 2.9 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence CBS PF00571.23 EXF80371.1 - 0.11 12.3 0.1 5.5 6.8 0.0 2.5 2 0 0 2 2 2 0 CBS domain Aminotran_3 PF00202.16 EXF80372.1 - 5.4e-98 327.9 0.0 6.4e-98 327.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EXF80372.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II SRI PF08236.6 EXF80374.1 - 7.4e-23 80.3 3.8 2.8e-22 78.4 2.6 2.1 1 0 0 1 1 1 1 SRI (Set2 Rpb1 interacting) domain SET PF00856.23 EXF80374.1 - 1.2e-21 77.7 0.2 1.2e-21 77.7 0.2 3.4 2 2 0 2 2 2 1 SET domain Med26 PF08711.6 EXF80374.1 - 5.5e-05 22.5 0.3 0.00014 21.2 0.2 1.7 1 0 0 1 1 1 1 TFIIS helical bundle-like domain WW PF00397.21 EXF80374.1 - 0.029 14.2 0.5 0.074 12.9 0.4 1.8 1 0 0 1 1 1 0 WW domain DUF2431 PF10354.4 EXF80375.1 - 3.4e-49 166.9 0.0 3.4e-34 118.1 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF2431) BUD22 PF09073.5 EXF80375.1 - 0.0021 17.2 8.1 0.0021 17.2 5.6 3.0 2 1 1 3 3 3 2 BUD22 Methyltransf_26 PF13659.1 EXF80375.1 - 0.017 15.1 0.0 0.024 14.6 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain CASP_C PF08172.7 EXF80375.1 - 2.4 7.1 7.8 0.21 10.5 1.6 1.9 2 0 0 2 2 2 0 CASP C terminal MA3 PF02847.12 EXF80376.1 - 0.15 11.7 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 MA3 domain YcbB PF08664.5 EXF80376.1 - 0.19 11.5 0.1 0.4 10.4 0.1 1.4 1 0 0 1 1 1 0 YcbB domain ThiF PF00899.16 EXF80377.1 - 3.8e-15 55.9 0.0 6.8e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 ThiF family DHFR_1 PF00186.14 EXF80379.1 - 7.7e-31 106.8 0.0 4.2e-30 104.4 0.0 2.0 2 1 0 2 2 2 1 Dihydrofolate reductase ketoacyl-synt PF00109.21 EXF80380.1 - 4.4e-61 206.5 0.5 4.4e-61 206.5 0.3 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EXF80380.1 - 1.9e-34 118.0 3.4 1.9e-34 118.0 1.3 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EXF80380.1 - 6.3e-06 25.3 0.1 1.3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain OPT PF03169.10 EXF80381.1 - 2.4e-187 624.1 51.8 2.7e-187 623.9 35.9 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CcmD PF04995.9 EXF80381.1 - 1.8 8.3 5.2 0.31 10.8 0.1 2.4 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) DUF3295 PF11702.3 EXF80382.1 - 1.7e-135 452.9 32.7 2.7e-135 452.2 22.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) DUF1752 PF08550.5 EXF80382.1 - 5.8e-13 48.1 1.5 1.2e-12 47.1 1.0 1.6 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) VHS PF00790.14 EXF80384.1 - 2.6e-18 66.0 0.0 5.1e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 VHS domain GAT PF03127.9 EXF80384.1 - 1.4e-09 37.8 1.2 2.9e-09 36.7 0.8 1.5 1 0 0 1 1 1 1 GAT domain Ribosomal_60s PF00428.14 EXF80384.1 - 0.048 14.0 0.4 0.048 14.0 0.3 3.0 4 0 0 4 4 4 0 60s Acidic ribosomal protein SpdB PF05122.8 EXF80385.1 - 0.062 13.3 1.2 0.062 13.3 0.8 1.5 2 0 0 2 2 2 0 Mobile element transfer protein DUF2461 PF09365.5 EXF80386.1 - 2.7e-75 252.3 0.2 4.3e-75 251.7 0.2 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein (DUF2461) NmrA PF05368.8 EXF80387.1 - 4.2e-20 72.0 0.0 5e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF80387.1 - 2.4e-12 47.2 0.1 4.3e-12 46.4 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF80387.1 - 5.4e-08 32.5 0.4 0.00041 19.8 0.1 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EXF80387.1 - 0.038 13.9 0.4 0.074 12.9 0.3 1.5 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 EXF80387.1 - 0.079 12.6 0.6 0.15 11.7 0.2 1.7 1 1 1 2 2 2 0 KR domain DapB_N PF01113.15 EXF80387.1 - 0.099 12.5 1.0 0.61 10.0 0.7 2.1 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 EXF80387.1 - 0.12 11.2 0.2 0.22 10.3 0.2 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein Crystall_3 PF08964.5 EXF80388.1 - 0.014 15.1 0.2 3.8 7.3 0.0 2.1 1 1 1 2 2 2 0 Beta/Gamma crystallin Fungal_trans PF04082.13 EXF80389.1 - 1.2e-06 27.6 0.2 3.2e-06 26.2 0.2 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EXF80389.1 - 0.0012 19.0 3.7 0.0012 19.0 2.6 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EXF80389.1 - 0.0015 18.7 14.0 0.009 16.2 1.1 3.4 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2 PF00096.21 EXF80389.1 - 0.0027 17.9 3.5 0.0027 17.9 2.4 2.6 2 0 0 2 2 2 1 Zinc finger, C2H2 type PyrI_C PF02748.10 EXF80389.1 - 0.26 10.7 0.2 0.45 10.0 0.1 1.3 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Methyltransf_16 PF10294.4 EXF80390.1 - 2.1e-13 50.0 0.0 7.3e-12 45.0 0.0 2.0 1 1 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EXF80390.1 - 0.02 14.0 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EXF80390.1 - 0.032 14.8 0.0 0.052 14.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EXF80390.1 - 0.04 13.6 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 EXF80390.1 - 0.16 11.0 0.0 0.3 10.1 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Copper-fist PF00649.13 EXF80392.1 - 7.6e-19 66.6 0.7 1.5e-18 65.6 0.5 1.5 1 0 0 1 1 1 1 Copper fist DNA binding domain Surp PF01805.15 EXF80393.1 - 2.8e-15 55.7 0.0 5.9e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 Surp module EF-hand_1 PF00036.27 EXF80395.1 - 3.6e-30 100.9 9.8 8.1e-10 37.2 0.0 3.1 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EXF80395.1 - 1.3e-26 91.9 7.7 8.2e-13 47.7 0.3 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.1 EXF80395.1 - 1.9e-24 85.5 3.3 2.4e-18 66.0 0.3 2.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EXF80395.1 - 6.9e-22 75.3 3.9 6e-09 35.0 0.0 3.2 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.1 EXF80395.1 - 5.5e-20 69.7 7.4 5e-08 31.9 0.0 3.2 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.1 EXF80395.1 - 9.6e-11 41.4 0.2 3.4e-06 26.8 0.0 2.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EXF80395.1 - 2.3e-07 30.4 2.1 0.00062 19.4 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.5 EXF80395.1 - 8.7e-05 22.4 0.2 0.001 19.0 0.0 2.0 2 0 0 2 2 2 1 Ca2+ insensitive EF hand SPARC_Ca_bdg PF10591.4 EXF80395.1 - 0.00017 21.6 0.0 0.021 14.8 0.0 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region TerB PF05099.8 EXF80395.1 - 0.0027 17.4 0.4 0.49 10.1 0.0 2.0 1 1 1 2 2 2 2 Tellurite resistance protein TerB Tenui_NCP PF04876.7 EXF80395.1 - 0.0037 16.8 0.3 0.083 12.4 0.0 2.1 1 1 1 2 2 2 1 Tenuivirus major non-capsid protein UPF0154 PF03672.8 EXF80395.1 - 0.0038 16.8 0.0 2.8 7.6 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) GTPase_Cys_C PF12631.2 EXF80395.1 - 0.08 13.3 0.0 0.16 12.4 0.0 1.6 1 1 0 1 1 1 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE VCBS PF13517.1 EXF80395.1 - 0.24 11.7 2.1 0.82 10.0 1.1 2.0 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_10 PF14788.1 EXF80395.1 - 0.25 11.0 1.1 5.1 6.8 0.1 2.8 1 1 2 3 3 3 0 EF hand DAO PF01266.19 EXF80396.1 - 5.5e-47 160.4 0.1 1.2e-46 159.2 0.1 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EXF80396.1 - 5.7e-07 29.4 0.1 0.0077 16.0 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EXF80396.1 - 1.6e-06 28.0 0.0 3.4e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF80396.1 - 0.00062 19.6 0.0 0.15 11.8 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Ribosomal_S25 PF03297.10 EXF80396.1 - 0.0023 17.9 0.2 0.0049 16.8 0.1 1.4 1 0 0 1 1 1 1 S25 ribosomal protein Trp_halogenase PF04820.9 EXF80396.1 - 0.0045 15.6 0.0 0.45 9.0 0.0 2.1 2 0 0 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.19 EXF80396.1 - 0.0083 15.0 0.0 0.92 8.2 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain GIDA PF01134.17 EXF80396.1 - 0.009 14.9 0.0 0.033 13.0 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A K_oxygenase PF13434.1 EXF80396.1 - 0.019 13.9 0.0 0.039 12.8 0.0 1.5 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EXF80396.1 - 0.027 14.5 0.0 0.34 10.9 0.0 2.7 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF80396.1 - 0.037 13.1 0.0 0.095 11.7 0.0 1.6 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 EXF80396.1 - 0.045 14.1 0.0 0.1 13.0 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SOCS_box PF07525.11 EXF80396.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 SOCS box Saccharop_dh PF03435.13 EXF80396.1 - 0.063 12.2 0.0 0.091 11.7 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Strep_67kDa_ant PF06100.6 EXF80396.1 - 0.09 11.1 0.0 0.14 10.4 0.0 1.2 1 0 0 1 1 1 0 Streptococcal 67 kDa myosin-cross-reactive antigen like family SR-25 PF10500.4 EXF80396.1 - 1.5 8.2 5.7 2.1 7.7 3.9 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TBP PF00352.16 EXF80397.1 - 2.8e-70 231.6 0.1 4.3e-35 118.9 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EXF80397.1 - 0.00023 21.1 0.0 0.84 9.7 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) Pollen_allerg_2 PF01620.11 EXF80397.1 - 0.0021 18.3 0.8 0.003 17.8 0.5 1.4 1 1 0 1 1 1 1 Ribonuclease (pollen allergen) Lpp-LpqN PF10738.4 EXF80397.1 - 0.02 14.1 0.1 0.033 13.4 0.1 1.2 1 0 0 1 1 1 0 Probable lipoprotein LpqN ETF_QO PF05187.8 EXF80398.1 - 4.7e-45 152.0 0.0 7.8e-45 151.3 0.0 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase DAO PF01266.19 EXF80398.1 - 2.4e-09 36.5 0.9 0.00017 20.6 0.2 2.9 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF80398.1 - 2.3e-07 30.7 0.0 1.1e-06 28.5 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EXF80398.1 - 1.6e-06 27.2 0.4 0.0002 20.3 0.6 2.2 1 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EXF80398.1 - 2.7e-05 24.1 0.0 5.1e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF80398.1 - 7.3e-05 21.4 0.5 0.00011 20.8 0.4 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EXF80398.1 - 9.1e-05 21.6 0.0 0.00034 19.7 0.1 1.7 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 EXF80398.1 - 0.00025 20.2 0.1 0.00053 19.1 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EXF80398.1 - 0.00027 21.2 0.1 1.2 9.6 0.1 3.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EXF80398.1 - 0.00069 18.3 0.3 0.052 12.1 0.1 2.4 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_9 PF13454.1 EXF80398.1 - 0.00094 18.9 0.1 0.0028 17.4 0.1 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EXF80398.1 - 0.0011 18.1 0.2 0.0021 17.1 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EXF80398.1 - 0.0018 18.4 0.1 0.017 15.1 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF80398.1 - 0.0034 16.3 0.2 0.0051 15.7 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Fer4_7 PF12838.2 EXF80398.1 - 0.011 16.0 0.9 0.032 14.6 0.6 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain GIDA PF01134.17 EXF80398.1 - 0.05 12.4 0.1 0.074 11.8 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Glyco_hydro_92 PF07971.7 EXF80399.1 - 9.9e-169 562.1 0.2 1.2e-168 561.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 DUF1237 PF06824.6 EXF80400.1 - 1.5e-159 531.1 0.0 1.7e-159 530.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) HECT PF00632.20 EXF80401.1 - 2.1e-83 280.0 0.0 4.1e-83 279.1 0.0 1.4 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.22 EXF80401.1 - 0.023 14.2 3.7 0.064 12.9 2.5 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif RRM_1 PF00076.17 EXF80402.1 - 2e-83 274.0 7.7 1.1e-21 76.2 0.2 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF80402.1 - 5.2e-55 183.3 1.2 2.7e-15 56.0 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF80402.1 - 4e-40 135.4 0.1 5.2e-09 35.8 0.0 5.4 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EXF80402.1 - 1.2e-27 95.3 1.1 5.3e-27 93.2 0.7 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain CbiG_mid PF11761.3 EXF80402.1 - 7.4e-05 22.9 0.4 4.2 7.6 0.0 4.2 4 0 0 4 4 4 2 Cobalamin biosynthesis central region Limkain-b1 PF11608.3 EXF80402.1 - 0.00014 21.5 1.3 1.8 8.3 0.1 3.6 3 0 0 3 3 3 1 Limkain b1 Nup35_RRM_2 PF14605.1 EXF80402.1 - 0.00028 20.5 0.3 9.4 6.0 0.0 4.8 4 1 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Nab6_mRNP_bdg PF10567.4 EXF80402.1 - 0.017 14.1 1.9 0.024 13.6 0.4 1.8 2 0 0 2 2 2 0 RNA-recognition motif OB_RNB PF08206.6 EXF80402.1 - 0.022 14.2 1.7 5.9 6.4 0.0 3.6 3 0 0 3 3 3 0 Ribonuclease B OB domain RNA_polI_A34 PF08208.6 EXF80402.1 - 0.04 13.5 15.7 0.084 12.5 10.9 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 CDC45 PF02724.9 EXF80402.1 - 0.82 7.6 11.9 1.3 6.9 8.3 1.3 1 0 0 1 1 1 0 CDC45-like protein Thiolase_N PF00108.18 EXF80403.1 - 2.2e-78 262.8 3.3 3.1e-78 262.4 2.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EXF80403.1 - 5e-41 138.9 0.3 1.1e-40 137.9 0.2 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.5 EXF80403.1 - 0.0059 16.6 0.0 0.032 14.2 0.0 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal NMO PF03060.10 EXF80404.1 - 5.3e-62 209.8 0.4 9.5e-62 209.0 0.3 1.4 1 1 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EXF80404.1 - 1.5e-11 43.7 0.0 1.3e-05 24.2 0.0 2.1 1 1 1 2 2 2 2 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.13 EXF80404.1 - 0.0015 17.4 0.6 0.0024 16.8 0.2 1.5 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 EXF80404.1 - 0.041 13.1 0.4 0.12 11.6 0.0 1.9 2 0 0 2 2 2 0 Histidine biosynthesis protein NIL PF09383.5 EXF80404.1 - 0.086 12.4 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 NIL domain NanE PF04131.9 EXF80404.1 - 0.23 10.4 0.0 0.23 10.4 0.0 1.6 2 0 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase Bul1_N PF04425.7 EXF80405.1 - 5.8e-07 28.4 0.9 0.00033 19.3 0.0 3.1 2 1 1 3 3 3 2 Bul1 N terminus Arrestin_N PF00339.24 EXF80405.1 - 2.2e-05 24.3 0.0 0.00013 21.8 0.0 2.2 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Bul1_C PF04426.7 EXF80405.1 - 7.6e-05 22.0 0.0 0.00014 21.2 0.0 1.4 1 0 0 1 1 1 1 Bul1 C terminus Zip PF02535.17 EXF80407.1 - 1.7e-56 191.5 5.3 8.2e-56 189.3 3.7 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter Senescence PF06911.7 EXF80410.1 - 8.9e-48 162.3 2.7 1.3e-47 161.7 1.8 1.3 1 0 0 1 1 1 1 Senescence-associated protein Spc97_Spc98 PF04130.8 EXF80411.1 - 2.5e-74 250.5 0.0 3.3e-74 250.1 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family adh_short PF00106.20 EXF80413.1 - 1.7e-31 109.4 1.2 2.3e-31 108.9 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF80413.1 - 4.7e-28 98.5 0.1 6.2e-28 98.1 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF80413.1 - 3e-12 46.5 0.2 4.3e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF80413.1 - 8.6e-06 25.3 0.1 2.5e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family PA PF02225.17 EXF80413.1 - 0.00027 20.5 0.2 0.00073 19.1 0.1 1.7 1 0 0 1 1 1 1 PA domain Polysacc_synt_2 PF02719.10 EXF80413.1 - 0.024 13.5 0.0 0.038 12.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Methyltransf_25 PF13649.1 EXF80413.1 - 0.14 12.5 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain ARID PF01388.16 EXF80414.1 - 1.4e-18 66.4 0.0 3.4e-18 65.2 0.0 1.6 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Trns_repr_metal PF02583.12 EXF80414.1 - 0.016 15.3 0.4 0.056 13.6 0.0 2.1 2 0 0 2 2 2 0 Metal-sensitive transcriptional repressor HECT PF00632.20 EXF80417.1 - 3.9e-67 226.6 0.0 5.7e-67 226.1 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) zf-C2H2_2 PF12756.2 EXF80418.1 - 1.5e-35 121.3 12.9 7.5e-30 103.0 3.0 3.6 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EXF80418.1 - 3e-07 30.3 4.1 3e-07 30.3 2.8 4.5 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EXF80418.1 - 8.6e-07 28.9 3.2 8.6e-07 28.9 2.2 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EXF80418.1 - 1.9e-05 24.4 4.0 0.086 12.7 1.2 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger SnoaL_2 PF12680.2 EXF80418.1 - 0.0099 16.2 3.1 0.045 14.1 1.2 2.4 2 0 0 2 2 2 1 SnoaL-like domain zf-C2H2 PF00096.21 EXF80418.1 - 0.43 11.0 21.3 3.2 8.2 0.5 5.0 4 0 0 4 4 4 0 Zinc finger, C2H2 type MMR_HSR1 PF01926.18 EXF80419.1 - 6.4e-19 68.0 0.0 1e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EXF80419.1 - 1.2e-08 34.9 0.0 0.00089 19.1 0.1 2.4 2 0 0 2 2 2 2 Dynamin family FeoB_N PF02421.13 EXF80419.1 - 4.7e-06 25.9 0.0 0.0002 20.6 0.0 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EXF80419.1 - 1e-05 25.0 0.0 3.2e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IIGP PF05049.8 EXF80419.1 - 2.5e-05 23.3 0.0 0.041 12.7 0.0 2.1 2 0 0 2 2 2 2 Interferon-inducible GTPase (IIGP) Miro PF08477.8 EXF80419.1 - 0.00073 20.0 0.1 0.0079 16.6 0.1 2.2 1 1 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 EXF80419.1 - 0.016 14.4 0.1 0.046 12.9 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 SRPRB PF09439.5 EXF80419.1 - 0.019 14.1 0.0 5.8 6.0 0.0 2.3 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Septin PF00735.13 EXF80419.1 - 0.035 13.1 0.0 0.16 10.9 0.0 1.9 1 1 0 1 1 1 0 Septin AIG1 PF04548.11 EXF80419.1 - 0.043 12.9 0.0 7.6 5.5 0.0 2.3 2 0 0 2 2 2 0 AIG1 family GBP PF02263.14 EXF80419.1 - 0.063 12.3 0.0 0.094 11.7 0.0 1.2 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain ABC_tran PF00005.22 EXF80419.1 - 0.095 12.9 0.0 2.2 8.5 0.0 2.5 2 1 0 2 2 2 0 ABC transporter zf-C3HC PF07967.8 EXF80420.1 - 8.3e-39 132.4 1.1 1.2e-34 118.9 0.3 2.6 3 0 0 3 3 3 2 C3HC zinc finger-like Rsm1 PF08600.5 EXF80420.1 - 8.9e-27 92.7 1.4 7e-25 86.7 0.0 2.5 2 0 0 2 2 2 2 Rsm1-like BIR PF00653.16 EXF80420.1 - 1.4e-05 25.4 0.1 0.00052 20.3 0.0 2.5 2 0 0 2 2 2 1 Inhibitor of Apoptosis domain SRP40_C PF05022.7 EXF80421.1 - 4.1e-23 81.6 0.3 4.1e-23 81.6 0.2 2.7 3 0 0 3 3 3 1 SRP40, C-terminal domain A_deaminase PF00962.17 EXF80422.1 - 7.6e-46 156.5 0.0 2.5e-45 154.8 0.0 1.9 1 1 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 EXF80422.1 - 0.00045 20.1 1.6 0.0024 17.8 1.1 2.2 1 1 0 1 1 1 1 Adenosine/AMP deaminase N-terminal DUF3490 PF11995.3 EXF80422.1 - 0.039 13.5 0.1 0.1 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) MCR_alpha PF02249.12 EXF80422.1 - 0.15 12.0 0.2 0.34 10.9 0.1 1.5 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Cupin_2 PF07883.6 EXF80423.1 - 1.9e-10 40.0 0.5 1.7e-05 24.2 0.0 3.1 3 0 0 3 3 3 2 Cupin domain Cupin_1 PF00190.17 EXF80423.1 - 4.7e-05 22.8 0.2 0.051 13.0 0.0 2.7 2 0 0 2 2 2 2 Cupin Cupin_6 PF12852.2 EXF80423.1 - 9.8e-05 22.0 0.0 0.19 11.2 0.0 2.5 2 0 0 2 2 2 2 Cupin Cupin_3 PF05899.7 EXF80423.1 - 0.00028 20.1 0.0 0.03 13.6 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF861) GMC_oxred_N PF00732.14 EXF80424.1 - 1.1e-51 175.7 0.0 1.4e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF80424.1 - 2.1e-32 112.4 0.0 4e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EXF80424.1 - 1e-06 27.9 5.0 5.9e-06 25.4 3.5 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF80424.1 - 0.00059 19.8 0.2 0.0018 18.2 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EXF80424.1 - 0.0016 17.3 1.1 0.027 13.3 0.0 2.6 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.9 EXF80424.1 - 0.004 17.0 0.1 0.09 12.6 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF80424.1 - 0.0045 16.1 0.0 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EXF80424.1 - 0.0096 16.0 0.0 0.17 11.9 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF80424.1 - 0.011 15.5 0.1 0.031 14.0 0.0 1.9 2 0 0 2 2 2 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EXF80424.1 - 0.014 13.9 0.1 0.5 8.7 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein TrkA_N PF02254.13 EXF80424.1 - 0.02 14.8 0.5 0.12 12.3 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain FAD_binding_1 PF00667.15 EXF80425.1 - 2.3e-57 193.9 0.0 7.6e-57 192.2 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.16 EXF80425.1 - 2e-10 41.2 0.0 7.5e-10 39.3 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain POR PF01558.13 EXF80425.1 - 1.8e-09 37.7 0.0 4.2e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase Transketolase_C PF02780.15 EXF80425.1 - 0.0025 17.7 0.1 0.0091 15.9 0.1 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1-E2_ATPase PF00122.15 EXF80426.1 - 2e-50 170.9 0.6 4.3e-49 166.6 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EXF80426.1 - 9.9e-38 130.7 1.4 1.9e-37 129.7 1.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EXF80426.1 - 2.9e-33 113.7 0.8 8.6e-11 41.8 0.1 4.8 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 EXF80426.1 - 1e-16 61.6 0.0 2.4e-16 60.4 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EXF80426.1 - 6.6e-06 25.8 0.1 0.00023 20.8 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Tox-PL-2 PF15643.1 EXF80426.1 - 0.00089 19.2 0.4 1.3 9.0 0.0 4.1 4 0 0 4 4 4 1 Papain fold toxin 2 HAD_2 PF13419.1 EXF80426.1 - 0.085 13.0 0.0 0.52 10.5 0.0 2.3 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Toxin-deaminase PF14424.1 EXF80426.1 - 0.085 12.8 0.6 5.2 7.0 0.0 2.9 3 0 0 3 3 3 0 The BURPS668_1122 family of deaminases Pox_E10 PF04805.7 EXF80426.1 - 0.18 11.3 1.2 6 6.4 0.1 3.2 3 0 0 3 3 3 0 E10-like protein conserved region RseC_MucC PF04246.7 EXF80426.1 - 0.44 10.1 4.9 0.75 9.3 0.7 3.1 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC Cyclin_N PF00134.18 EXF80427.1 - 1.2e-12 47.5 0.0 2.1e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EXF80427.1 - 3.9e-11 43.5 0.2 2.1e-10 41.2 0.1 2.0 1 1 0 1 1 1 1 Cyclin DUF3812 PF12757.2 EXF80427.1 - 0.085 12.8 2.4 0.18 11.7 1.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3812) DUF566 PF04484.7 EXF80427.1 - 2 7.8 6.7 3.6 6.9 4.7 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) EF-hand_6 PF13405.1 EXF80430.1 - 6 7.0 6.4 30 4.8 0.2 2.7 2 0 0 2 2 2 0 EF-hand domain 4HBT PF03061.17 EXF80431.1 - 1.8e-11 44.0 0.0 2.5e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EXF80431.1 - 3.3e-05 23.7 0.1 7.5e-05 22.5 0.0 1.6 1 1 1 2 2 2 1 Thioesterase-like superfamily Pex2_Pex12 PF04757.9 EXF80432.1 - 6.3e-56 189.3 2.6 7.9e-56 189.0 1.8 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EXF80432.1 - 9.3e-05 22.3 3.1 0.00015 21.6 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EXF80432.1 - 0.0011 18.8 3.7 0.0017 18.1 2.6 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EXF80432.1 - 0.0044 16.8 1.9 0.0068 16.2 1.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EXF80432.1 - 0.16 11.6 2.4 0.28 10.8 1.6 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Glyco_hydro_16 PF00722.16 EXF80433.1 - 5.6e-08 32.2 0.0 1.9e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 Metallophos PF00149.23 EXF80434.1 - 8e-10 38.4 3.5 1.4e-05 24.5 0.3 2.4 2 1 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EXF80434.1 - 1.6e-05 24.7 0.1 3e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Anoctamin PF04547.7 EXF80435.1 - 4.6e-122 407.9 8.7 5.8e-122 407.5 6.0 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel SH3_9 PF14604.1 EXF80436.1 - 6.7e-12 44.7 0.5 1.6e-11 43.6 0.4 1.7 1 0 0 1 1 1 1 Variant SH3 domain tRNA-synt_2d PF01409.15 EXF80437.1 - 1.8e-48 164.8 0.4 5.5e-25 87.9 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EXF80437.1 - 1.2e-24 86.2 0.0 2.7e-24 85.1 0.0 1.6 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Calcipressin PF04847.7 EXF80439.1 - 3.9e-50 170.0 0.1 4.7e-50 169.7 0.1 1.1 1 0 0 1 1 1 1 Calcipressin DUF2236 PF09995.4 EXF80440.1 - 2.4e-33 115.4 3.5 4e-33 114.7 0.7 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF1076 PF06416.7 EXF80440.1 - 0.051 13.2 0.0 0.091 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1076) Neugrin PF06413.6 EXF80441.1 - 1.5e-10 41.2 0.2 1.5e-10 41.2 0.2 1.7 2 1 0 2 2 2 1 Neugrin MRP-L20 PF12824.2 EXF80441.1 - 2.5e-06 27.5 2.7 2.5e-06 27.5 1.9 2.0 2 1 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 HTH_29 PF13551.1 EXF80441.1 - 0.087 12.9 0.1 0.087 12.9 0.0 2.3 2 1 0 2 2 2 0 Winged helix-turn helix Sigma70_r4 PF04545.11 EXF80441.1 - 0.3 10.4 2.0 0.59 9.4 0.0 2.4 3 0 0 3 3 3 0 Sigma-70, region 4 HET PF06985.6 EXF80442.1 - 1.5e-17 64.0 0.0 4.5e-17 62.5 0.0 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ATP-grasp_2 PF08442.5 EXF80443.1 - 2.5e-77 258.8 0.6 2.5e-77 258.8 0.4 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 EXF80443.1 - 3.1e-27 95.0 0.4 6.5e-27 94.0 0.3 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EXF80443.1 - 1.4e-06 27.7 0.1 3.2e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 EXF80443.1 - 0.001 18.6 2.2 0.024 14.1 0.1 2.6 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Peripla_BP_2 PF01497.13 EXF80443.1 - 0.0025 16.9 0.3 0.0044 16.1 0.2 1.3 1 0 0 1 1 1 1 Periplasmic binding protein ATP-grasp_4 PF13535.1 EXF80443.1 - 0.019 14.6 0.0 0.033 13.9 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain AzlD PF05437.7 EXF80444.1 - 0.029 14.2 0.3 0.058 13.3 0.2 1.5 1 0 0 1 1 1 0 Branched-chain amino acid transport protein (AzlD) Fructosamin_kin PF03881.9 EXF80446.1 - 2.1e-73 246.7 0.0 2.5e-73 246.5 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EXF80446.1 - 9.8e-05 22.1 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1679 PF07914.6 EXF80446.1 - 0.083 11.5 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) RHD3 PF05879.7 EXF80447.1 - 0 1058.9 0.0 0 1058.6 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GBP PF02263.14 EXF80447.1 - 5.3e-10 38.7 0.4 8.7e-10 38.0 0.3 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EXF80447.1 - 1.3e-07 31.6 0.1 2.5e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EXF80447.1 - 0.0001 22.2 0.1 0.00025 21.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.1 EXF80447.1 - 0.00018 21.5 0.0 0.00074 19.5 0.0 2.1 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EXF80447.1 - 0.00038 20.9 0.1 0.00078 19.9 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 EXF80447.1 - 0.022 13.7 0.2 0.037 13.0 0.1 1.3 1 0 0 1 1 1 0 Septin GTP_EFTU PF00009.22 EXF80447.1 - 0.11 11.9 0.1 0.45 9.9 0.0 1.9 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain CENP-C_C PF11699.3 EXF80448.1 - 6.9e-34 115.6 0.3 1.2e-33 114.8 0.2 1.4 1 0 0 1 1 1 1 Mif2/CENP-C like Mif2_N PF15624.1 EXF80448.1 - 3.1e-33 115.2 2.9 3.1e-33 115.2 2.0 3.9 3 1 1 4 4 4 1 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Cupin_2 PF07883.6 EXF80448.1 - 1.7e-07 30.6 0.0 4.9e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EXF80448.1 - 0.0023 17.3 0.0 0.0063 15.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EXF80448.1 - 0.0069 16.0 0.0 0.022 14.3 0.0 1.8 1 0 0 1 1 1 1 Cupin Cupin_1 PF00190.17 EXF80448.1 - 0.056 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 Cupin RNase_HII PF01351.13 EXF80449.1 - 4.2e-45 153.8 0.0 5.5e-45 153.4 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII HSP70 PF00012.15 EXF80451.1 - 1.1e-269 895.4 6.4 1.3e-269 895.2 4.4 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EXF80451.1 - 4.5e-17 61.6 0.1 1.1e-15 57.1 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EXF80451.1 - 0.0019 17.8 0.0 0.0039 16.8 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EXF80451.1 - 0.0048 16.0 0.1 0.033 13.2 0.0 2.2 1 1 1 2 2 2 1 Hydantoinase/oxoprolinase BcrAD_BadFG PF01869.15 EXF80451.1 - 0.022 14.0 0.0 1.8 7.7 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.1 EXF80451.1 - 0.052 13.3 3.2 1.3 8.8 0.2 3.1 2 2 0 2 2 2 0 Cell division protein FtsA DUF3128 PF11326.3 EXF80452.1 - 1e-28 99.2 3.9 1.7e-28 98.5 2.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) DUF566 PF04484.7 EXF80452.1 - 4.9 6.5 9.1 7.7 5.9 6.3 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF566) RNA12 PF10443.4 EXF80453.1 - 1.3e-158 528.0 0.4 1.3e-158 528.0 0.2 1.4 2 0 0 2 2 2 1 RNA12 protein RRM_1 PF00076.17 EXF80453.1 - 7.4e-06 25.5 0.0 3.5e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF80453.1 - 2.1e-05 24.2 0.0 5.2e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Arch_ATPase PF01637.13 EXF80453.1 - 0.00085 19.0 1.3 0.014 15.0 0.9 2.5 1 1 0 1 1 1 1 Archaeal ATPase RRM_6 PF14259.1 EXF80453.1 - 0.013 15.4 0.0 0.093 12.7 0.0 2.4 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2487 PF10673.4 EXF80453.1 - 0.021 14.6 0.0 0.042 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2487) AAA_16 PF13191.1 EXF80453.1 - 0.059 13.3 0.2 0.83 9.6 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain HSP70 PF00012.15 EXF80454.1 - 3.3e-05 22.0 0.0 4.2e-05 21.6 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein Sugar_tr PF00083.19 EXF80455.1 - 2e-85 287.0 24.4 2.4e-85 286.8 16.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF80455.1 - 1.6e-12 46.8 47.7 5.7e-10 38.4 23.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SpoIIIAC PF06686.6 EXF80455.1 - 0.044 13.5 1.4 0.21 11.3 0.0 2.4 2 0 0 2 2 2 0 Stage III sporulation protein AC/AD protein family MS_channel PF00924.13 EXF80456.1 - 1.1e-18 67.3 2.9 1.7e-18 66.7 2.0 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.27 EXF80456.1 - 0.013 14.7 0.4 0.036 13.3 0.3 1.7 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.1 EXF80456.1 - 0.025 14.7 0.0 0.061 13.4 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.1 EXF80456.1 - 0.068 13.0 0.0 0.24 11.3 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain DLH PF01738.13 EXF80457.1 - 3.5e-24 85.3 0.0 4.7e-24 84.8 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EXF80457.1 - 4.7e-05 23.1 0.1 6.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abp2 PF09441.5 EXF80458.1 - 3.1e-89 297.5 0.0 4.7e-89 296.9 0.0 1.2 1 0 0 1 1 1 1 ARS binding protein 2 Sds3 PF08598.6 EXF80460.1 - 2.9e-50 170.6 3.6 3.9e-50 170.2 2.5 1.3 1 0 0 1 1 1 1 Sds3-like SLAC1 PF03595.12 EXF80461.1 - 1.4e-51 175.1 37.6 2e-51 174.6 26.1 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel COG5 PF10392.4 EXF80461.1 - 0.0088 15.9 0.3 0.1 12.5 0.0 2.8 3 1 0 3 3 3 1 Golgi transport complex subunit 5 TrbI PF03743.9 EXF80461.1 - 0.077 12.4 0.0 0.22 11.0 0.0 1.7 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein DUF4366 PF14283.1 EXF80463.1 - 0.046 13.1 0.1 0.048 13.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Ribosomal_S5_C PF03719.10 EXF80464.1 - 6.2e-18 63.8 0.1 4.1e-17 61.2 0.0 2.4 3 0 0 3 3 3 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.15 EXF80464.1 - 8e-10 38.3 0.4 2.3e-09 36.8 0.3 1.8 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain DASH_Dad3 PF08656.5 EXF80465.1 - 9.2e-30 102.1 0.4 1.1e-29 101.9 0.2 1.1 1 0 0 1 1 1 1 DASH complex subunit Dad3 CorA PF01544.13 EXF80466.1 - 9.5e-05 21.5 0.0 0.00017 20.7 0.0 1.3 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein PARP PF00644.15 EXF80467.1 - 8.4e-15 54.7 0.0 1.8e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain UQ_con PF00179.21 EXF80467.1 - 3.3e-06 26.5 0.0 1.1e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EXF80467.1 - 0.06 13.1 0.0 0.15 11.8 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family B PP2C PF00481.16 EXF80468.1 - 1.7e-41 142.3 0.0 2.7e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EXF80468.1 - 0.0082 15.5 0.1 0.019 14.4 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EXF80468.1 - 0.0086 15.7 0.1 0.45 10.1 0.0 2.7 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) Phosphoprotein PF00922.12 EXF80468.1 - 0.097 11.8 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Pkinase PF00069.20 EXF80469.1 - 1.4e-70 237.4 0.0 2.3e-70 236.7 0.0 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF80469.1 - 3.8e-30 104.8 0.0 7.1e-29 100.6 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF80469.1 - 8.1e-06 24.9 0.0 0.4 9.5 0.0 3.1 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 EXF80469.1 - 0.033 13.2 0.0 0.054 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EXF80469.1 - 0.11 12.2 0.0 3 7.5 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-C2H2_4 PF13894.1 EXF80470.1 - 1.5 9.3 3.8 18 5.9 0.2 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger adh_short PF00106.20 EXF80471.1 - 2.6e-17 63.2 0.2 3.6e-17 62.7 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF80471.1 - 3.1e-07 30.4 0.0 3.9e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF80471.1 - 1.4e-06 28.0 0.1 2.6e-06 27.2 0.1 1.4 1 1 0 1 1 1 1 KR domain zf-CCCH PF00642.19 EXF80472.1 - 1e-05 25.0 9.0 1.6e-05 24.4 1.3 2.8 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ost4 PF10215.4 EXF80473.1 - 8.7e-19 66.7 0.4 1.4e-18 66.1 0.3 1.3 1 0 0 1 1 1 1 Oligosaccaryltransferase RRM_1 PF00076.17 EXF80474.1 - 2.4e-15 55.8 0.0 4e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF80474.1 - 6.7e-13 48.4 0.0 1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF80474.1 - 4.4e-07 29.6 0.0 8.3e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EXF80474.1 - 0.0001 22.6 2.5 0.0001 22.6 1.8 3.2 2 1 1 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Smg4_UPF3 PF03467.10 EXF80474.1 - 0.0029 17.6 0.0 0.0037 17.2 0.0 1.2 1 0 0 1 1 1 1 Smg-4/UPF3 family CS PF04969.11 EXF80475.1 - 3.2e-12 46.8 0.1 5.4e-12 46.0 0.0 1.3 1 0 0 1 1 1 1 CS domain Snf7 PF03357.16 EXF80476.1 - 7.3e-25 87.3 13.3 7.3e-25 87.3 9.2 1.9 2 0 0 2 2 2 1 Snf7 DUF3069 PF11269.3 EXF80476.1 - 0.19 11.8 0.0 0.19 11.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) DASH_Duo1 PF08651.5 EXF80476.1 - 0.29 10.7 2.6 1.8 8.2 0.2 2.8 2 1 1 3 3 3 0 DASH complex subunit Duo1 GAS PF13851.1 EXF80476.1 - 2.3 7.3 14.1 0.14 11.2 4.7 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 EXF80476.1 - 5.5 6.7 14.2 23 4.7 9.8 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein bZIP_1 PF00170.16 EXF80477.1 - 5.1e-07 29.5 2.6 7.5e-07 29.0 1.8 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EXF80477.1 - 4e-05 23.3 4.5 6.7e-05 22.6 3.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper DUF737 PF05300.6 EXF80477.1 - 0.011 15.6 0.4 0.015 15.2 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) S1-P1_nuclease PF02265.11 EXF80478.1 - 3.5e-70 236.4 0.1 4.1e-70 236.2 0.1 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease W_rich_C PF07483.6 EXF80478.1 - 0.24 11.0 1.5 7.7 6.2 0.0 2.8 3 0 0 3 3 3 0 Tryptophan-rich Synechocystis species C-terminal domain PSI_PSAK PF01241.13 EXF80478.1 - 0.28 11.2 2.9 0.56 10.2 2.0 1.4 1 0 0 1 1 1 0 Photosystem I psaG / psaK PQ-loop PF04193.9 EXF80479.1 - 1.6e-40 136.4 7.1 1.7e-21 75.5 0.1 2.7 2 0 0 2 2 2 2 PQ loop repeat DUF202 PF02656.10 EXF80479.1 - 1.5 9.0 6.0 93 3.3 0.0 3.8 3 1 0 3 3 3 0 Domain of unknown function (DUF202) F-box-like PF12937.2 EXF80480.1 - 1.9e-06 27.4 0.6 6.8e-06 25.7 0.4 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EXF80480.1 - 2.8e-05 23.6 0.5 0.00013 21.5 0.1 2.3 2 0 0 2 2 2 1 F-box domain Bac_rhamnosid PF05592.6 EXF80481.1 - 3.9e-24 84.7 5.9 5e-19 67.8 4.4 2.4 1 1 1 2 2 2 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 EXF80481.1 - 0.00029 19.6 1.8 0.00047 18.9 1.3 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF608 GDE_C PF06202.9 EXF80481.1 - 0.017 13.8 0.1 0.26 9.9 0.1 2.1 1 1 0 1 1 1 0 Amylo-alpha-1,6-glucosidase DUF1973 PF09315.6 EXF80481.1 - 0.025 14.0 0.3 0.72 9.2 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1973) Epimerase_Csub PF13950.1 EXF80481.1 - 0.18 11.7 1.7 0.19 11.7 0.0 2.0 2 0 0 2 2 2 0 UDP-glucose 4-epimerase C-term subunit CFEM PF05730.6 EXF80482.1 - 1.1e-13 50.8 9.7 2e-13 49.9 6.8 1.5 1 0 0 1 1 1 1 CFEM domain GMC_oxred_N PF00732.14 EXF80483.1 - 4.3e-26 91.7 0.0 6.5e-18 64.9 0.0 3.1 2 1 0 3 3 3 3 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF80483.1 - 1.2e-21 77.5 0.0 2e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.1 EXF80483.1 - 0.00039 20.3 0.2 0.0012 18.8 0.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF80483.1 - 0.00052 19.9 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF80483.1 - 0.0048 15.8 0.2 0.0068 15.3 0.1 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EXF80483.1 - 0.0065 15.4 0.4 0.031 13.1 0.2 2.1 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF80483.1 - 0.0083 15.0 0.3 0.025 13.4 0.1 1.8 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EXF80483.1 - 0.0085 16.1 0.0 1.2 9.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EXF80483.1 - 0.01 14.9 0.1 0.015 14.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EXF80483.1 - 0.055 11.9 0.1 0.078 11.4 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein EI24 PF07264.6 EXF80485.1 - 2.3e-06 27.2 10.4 8.4e-06 25.3 7.2 1.8 1 1 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) SPC12 PF06645.8 EXF80486.1 - 0.005 16.6 0.1 10 6.0 0.0 3.8 3 0 0 3 3 3 2 Microsomal signal peptidase 12 kDa subunit (SPC12) SURF4 PF02077.10 EXF80487.1 - 1.8e-97 325.8 8.6 2.1e-97 325.7 6.0 1.0 1 0 0 1 1 1 1 SURF4 family Peptidase_A24 PF01478.13 EXF80487.1 - 0.29 11.3 15.1 0.41 10.8 1.0 2.7 2 1 0 2 2 2 0 Type IV leader peptidase family Halogen_Hydrol PF10112.4 EXF80487.1 - 4.2 6.7 7.2 3.5 6.9 0.5 2.9 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Methyltransf_23 PF13489.1 EXF80488.1 - 3.9e-21 75.4 0.0 6.2e-21 74.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF80488.1 - 5.5e-12 45.5 0.0 3.4e-11 42.9 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF80488.1 - 6.1e-12 46.1 0.0 3.3e-11 43.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF80488.1 - 5.6e-10 39.5 0.0 2.5e-09 37.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF80488.1 - 1.6e-09 38.1 0.0 2.6e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF80488.1 - 6.2e-06 26.4 0.0 1.4e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF80488.1 - 0.0026 16.8 0.0 0.006 15.6 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EXF80488.1 - 0.023 14.0 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 EXF80488.1 - 0.035 13.2 0.0 0.55 9.3 0.0 2.6 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EXF80488.1 - 0.06 12.4 0.0 0.14 11.2 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EXF80488.1 - 0.089 12.8 0.0 0.33 10.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Tyrosinase PF00264.15 EXF80489.1 - 4.5e-26 92.3 0.8 1.1e-23 84.6 0.0 2.4 2 0 0 2 2 2 2 Common central domain of tyrosinase p450 PF00067.17 EXF80490.1 - 1.1e-69 235.1 0.0 1.4e-69 234.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 OCD_Mu_crystall PF02423.10 EXF80491.1 - 1.2e-19 70.2 0.0 5.4e-15 54.9 0.0 3.0 2 1 0 2 2 2 2 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EXF80491.1 - 6.6e-07 29.4 0.1 1.1e-05 25.5 0.1 2.2 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF4147 PF13660.1 EXF80491.1 - 0.023 13.8 0.0 0.039 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Saccharop_dh PF03435.13 EXF80491.1 - 0.056 12.4 0.0 0.091 11.7 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Oxidored_FMN PF00724.15 EXF80492.1 - 5.6e-73 245.8 0.0 1.4e-69 234.7 0.0 2.0 1 1 1 2 2 2 2 NADH:flavin oxidoreductase / NADH oxidase family Meth_synt_2 PF01717.13 EXF80493.1 - 2.2e-143 477.1 0.0 9.8e-137 455.2 0.0 2.4 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EXF80493.1 - 2.8e-125 417.7 0.0 3.9e-112 374.5 0.0 3.4 3 1 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.12 EXF80493.1 - 0.00027 19.9 0.0 0.041 12.8 0.0 2.8 3 0 0 3 3 3 2 Uroporphyrinogen decarboxylase (URO-D) DUF3018 PF11455.3 EXF80493.1 - 0.057 13.3 0.2 0.41 10.6 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3018) But2 PF09792.4 EXF80495.1 - 6.3e-05 22.7 0.0 8.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Clr5 PF14420.1 EXF80498.1 - 1.6e-20 72.7 3.5 4.6e-20 71.2 2.4 1.9 1 0 0 1 1 1 1 Clr5 domain YCII PF03795.9 EXF80498.1 - 0.65 10.2 0.0 0.65 10.2 0.0 2.5 3 0 0 3 3 3 0 YCII-related domain Med15 PF09606.5 EXF80498.1 - 0.71 7.9 48.4 0.96 7.5 33.6 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PH PF00169.24 EXF80499.1 - 3.6e-05 23.9 0.0 6.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 PH domain SapC PF07277.6 EXF80499.1 - 0.029 13.7 0.2 0.053 12.8 0.1 1.4 1 0 0 1 1 1 0 SapC Arrestin_N PF00339.24 EXF80500.1 - 1.8e-17 63.5 0.0 3.7e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EXF80500.1 - 5.4e-16 58.9 0.0 1.3e-15 57.7 0.0 1.6 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain LDB19 PF13002.2 EXF80500.1 - 0.0018 17.8 0.0 0.0048 16.4 0.0 1.7 2 0 0 2 2 2 1 Arrestin_N terminal like WD40 PF00400.27 EXF80501.1 - 8.1e-21 73.0 11.8 1.3e-05 24.8 0.6 5.8 5 0 0 5 5 5 3 WD domain, G-beta repeat eIF2A PF08662.6 EXF80501.1 - 0.00015 21.4 0.1 0.00069 19.3 0.0 1.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.7 EXF80501.1 - 0.00056 17.8 0.0 0.00081 17.3 0.0 1.1 1 0 0 1 1 1 1 IKI3 family PD40 PF07676.7 EXF80501.1 - 0.0037 16.8 0.6 1.7 8.3 0.0 3.2 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.11 EXF80501.1 - 0.0044 15.3 0.0 0.0071 14.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain Miro PF08477.8 EXF80502.1 - 5.5e-36 123.6 0.0 2.1e-19 70.1 0.0 2.4 2 0 0 2 2 2 2 Miro-like protein EF_assoc_2 PF08356.7 EXF80502.1 - 1.1e-34 118.0 0.0 2e-34 117.2 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.7 EXF80502.1 - 9.1e-33 111.3 0.5 2e-32 110.2 0.3 1.6 1 0 0 1 1 1 1 EF hand associated Ras PF00071.17 EXF80502.1 - 2.9e-21 75.5 0.0 1.5e-13 50.4 0.0 2.2 2 0 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 EXF80502.1 - 5e-09 36.1 0.0 0.00028 20.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_7 PF13499.1 EXF80502.1 - 4.8e-08 33.0 0.5 0.0011 19.1 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair AAA_16 PF13191.1 EXF80502.1 - 3.9e-07 30.2 0.2 0.0053 16.7 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EXF80502.1 - 1.7e-06 27.4 0.1 0.0027 17.1 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain EF-hand_1 PF00036.27 EXF80502.1 - 4.5e-06 25.5 3.3 0.031 13.5 0.5 2.7 2 0 0 2 2 2 2 EF hand AAA_22 PF13401.1 EXF80502.1 - 5.1e-06 26.6 0.0 0.1 12.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 EXF80502.1 - 8.3e-06 25.7 0.6 0.36 10.6 0.0 3.4 3 1 1 4 4 3 2 Dynamin family EF-hand_6 PF13405.1 EXF80502.1 - 2.1e-05 24.0 3.0 0.05 13.5 0.3 2.7 2 0 0 2 2 2 2 EF-hand domain ABC_tran PF00005.22 EXF80502.1 - 7.4e-05 23.0 0.0 0.23 11.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 EXF80502.1 - 0.00012 21.2 0.0 0.34 10.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_24 PF13479.1 EXF80502.1 - 0.00022 20.8 0.0 0.03 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EXF80502.1 - 0.001 19.2 0.0 0.36 11.0 0.0 2.6 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 EXF80502.1 - 0.0022 17.8 0.0 0.74 9.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EXF80502.1 - 0.0023 16.8 0.1 1 8.2 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) GTP_EFTU PF00009.22 EXF80502.1 - 0.0033 16.8 0.0 6.6 6.1 0.0 3.2 2 1 0 3 3 3 0 Elongation factor Tu GTP binding domain MobB PF03205.9 EXF80502.1 - 0.0037 16.9 0.0 0.23 11.1 0.1 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EXF80502.1 - 0.0037 17.2 0.0 3.1 7.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain IIGP PF05049.8 EXF80502.1 - 0.0069 15.2 0.0 1.4 7.6 0.0 2.3 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) NACHT PF05729.7 EXF80502.1 - 0.0084 15.7 0.0 1.9 8.1 0.0 2.8 3 0 0 3 3 2 1 NACHT domain EF-hand_5 PF13202.1 EXF80502.1 - 0.0091 15.3 6.1 0.14 11.5 1.9 2.7 2 0 0 2 2 2 1 EF hand Septin PF00735.13 EXF80502.1 - 0.0097 14.9 0.0 0.37 9.7 0.0 2.2 2 0 0 2 2 2 1 Septin AAA_23 PF13476.1 EXF80502.1 - 0.011 16.1 0.0 1.4 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EXF80502.1 - 0.015 14.6 0.0 1.7 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain EF-hand_10 PF14788.1 EXF80502.1 - 0.022 14.4 0.8 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 EF hand AAA_10 PF12846.2 EXF80502.1 - 0.045 13.1 0.0 8.2 5.7 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain Arch_ATPase PF01637.13 EXF80502.1 - 0.053 13.2 0.0 4 7.0 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase Arf PF00025.16 EXF80502.1 - 0.058 12.6 0.0 8.4 5.5 0.0 2.7 2 1 0 2 2 2 0 ADP-ribosylation factor family Viral_helicase1 PF01443.13 EXF80502.1 - 0.067 12.7 0.0 2.6 7.4 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase SMC_N PF02463.14 EXF80502.1 - 0.084 12.0 0.1 3.1 6.9 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EXF80502.1 - 0.11 13.3 0.0 27 5.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain PRK PF00485.13 EXF80502.1 - 0.15 11.6 0.0 5.3 6.5 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EXF80502.1 - 0.17 12.2 0.0 7.8 6.8 0.0 2.7 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EXF80502.1 - 0.17 11.3 0.1 17 4.8 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AIG1 PF04548.11 EXF80502.1 - 0.2 10.7 0.2 1 8.4 0.1 2.0 2 0 0 2 2 2 0 AIG1 family EF-hand_8 PF13833.1 EXF80502.1 - 1.2 8.7 4.0 4.2 7.0 0.6 2.5 2 0 0 2 2 2 0 EF-hand domain pair adh_short_C2 PF13561.1 EXF80503.1 - 6.2e-35 121.1 2.8 8.5e-35 120.6 1.9 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EXF80503.1 - 6.2e-33 114.0 5.4 1.1e-32 113.3 3.7 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF80503.1 - 5.3e-15 55.5 3.4 9.3e-15 54.7 2.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF80503.1 - 0.0035 16.8 2.1 0.0035 16.8 1.5 1.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.14 EXF80503.1 - 0.016 14.2 0.3 0.04 12.9 0.2 1.7 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.13 EXF80503.1 - 1.6 8.3 6.6 0.17 11.5 1.4 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Zds_C PF08632.5 EXF80504.1 - 2.4e-28 97.2 1.3 4.6e-28 96.3 0.9 1.5 1 0 0 1 1 1 1 Activator of mitotic machinery Cdc14 phosphatase activation C-term DUF2433 PF10360.4 EXF80505.1 - 5.4e-55 185.3 0.0 9.9e-55 184.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2433) Metallophos PF00149.23 EXF80505.1 - 0.0022 17.4 0.0 0.0043 16.4 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF2360 PF10152.4 EXF80505.1 - 0.0024 18.1 4.1 0.0095 16.2 2.9 1.9 1 1 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) Metallophos_2 PF12850.2 EXF80505.1 - 0.016 15.0 0.0 0.043 13.6 0.0 1.8 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Ubie_methyltran PF01209.13 EXF80506.1 - 2.5e-77 259.1 0.0 3.1e-77 258.8 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EXF80506.1 - 6e-14 51.9 0.0 8e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF80506.1 - 1.1e-12 48.2 0.0 2.3e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF80506.1 - 5.7e-12 45.9 0.0 8.7e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF80506.1 - 4.5e-11 43.0 0.0 6.7e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF80506.1 - 1.7e-10 40.8 0.0 2.5e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF80506.1 - 6.7e-08 33.0 0.0 1.1e-07 32.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF80506.1 - 8.2e-05 22.6 0.0 0.00024 21.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EXF80506.1 - 0.019 14.5 0.0 0.072 12.7 0.0 1.9 3 0 0 3 3 3 0 Hypothetical methyltransferase Aminotran_4 PF01063.14 EXF80507.1 - 1.5e-32 112.9 0.0 2.6e-32 112.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class IV Fungal_trans PF04082.13 EXF80507.1 - 2.7e-26 92.0 0.2 3.9e-26 91.4 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF80507.1 - 0.0024 17.7 3.2 0.0052 16.6 2.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4094 PF13334.1 EXF80507.1 - 0.084 13.2 0.0 0.25 11.7 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DUF4446 PF14584.1 EXF80507.1 - 0.23 11.2 0.6 0.94 9.2 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF4446) Occludin_ELL PF07303.8 EXF80507.1 - 0.41 11.4 1.3 2.1 9.1 0.0 2.6 3 0 0 3 3 3 0 Occludin homology domain MFS_1 PF07690.11 EXF80508.1 - 1.5e-34 119.2 25.9 1.5e-34 119.2 17.9 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily EIIBC-GUT_C PF07663.6 EXF80508.1 - 0.082 13.0 4.6 0.082 13.0 0.0 3.1 4 0 0 4 4 4 0 Sorbitol phosphotransferase enzyme II C-terminus UPF0182 PF03699.8 EXF80508.1 - 0.33 8.8 3.7 0.36 8.7 1.9 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0182) E1_dh PF00676.15 EXF80509.1 - 2.6e-86 289.0 0.0 3.1e-86 288.8 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EXF80509.1 - 9.5e-05 22.0 0.1 0.0053 16.3 0.0 2.9 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EXF80509.1 - 0.06 12.2 0.0 0.21 10.4 0.0 1.7 1 1 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase SGS PF05002.10 EXF80509.1 - 0.19 11.5 1.6 1.1 9.0 0.5 2.5 2 1 0 2 2 2 0 SGS domain MSP1_C PF07462.6 EXF80509.1 - 1.6 7.0 6.6 4.5 5.5 0.1 2.1 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus HECT PF00632.20 EXF80510.1 - 6.2e-83 278.5 0.0 9.5e-83 277.9 0.0 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) HEAT PF02985.17 EXF80510.1 - 0.0081 16.1 0.3 4.1 7.7 0.0 4.5 4 1 1 5 5 5 1 HEAT repeat RRN3 PF05327.6 EXF80510.1 - 0.023 12.8 9.4 0.0061 14.7 3.6 1.9 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Arm PF00514.18 EXF80510.1 - 0.19 11.6 8.7 71 3.4 0.0 6.8 8 2 2 10 10 10 0 Armadillo/beta-catenin-like repeat Sec3_C PF09763.4 EXF80511.1 - 3.4e-237 789.0 2.9 4.5e-237 788.6 2.0 1.0 1 0 0 1 1 1 1 Exocyst complex component Sec3 Sec3-PIP2_bind PF15277.1 EXF80511.1 - 1.9e-30 104.5 0.0 4.1e-30 103.4 0.0 1.6 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH Sec3_C_2 PF15278.1 EXF80511.1 - 0.01 15.9 0.0 0.031 14.4 0.0 1.8 1 0 0 1 1 1 0 Sec3 exocyst complex subunit HILPDA PF15220.1 EXF80511.1 - 0.089 12.7 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated Vps52 PF04129.7 EXF80511.1 - 1.9 6.8 8.2 0.048 12.1 0.2 2.1 3 0 0 3 3 3 0 Vps52 / Sac2 family End3 PF12761.2 EXF80511.1 - 3.9 7.0 7.7 0.75 9.4 1.0 2.8 3 1 1 4 4 4 0 Actin cytoskeleton-regulatory complex protein END3 HET PF06985.6 EXF80513.1 - 4e-05 23.7 0.6 6.1e-05 23.2 0.4 1.3 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Chromo_shadow PF01393.14 EXF80514.1 - 4.9e-12 45.4 0.0 2.3e-11 43.3 0.0 2.0 2 0 0 2 2 2 1 Chromo shadow domain Chromo PF00385.19 EXF80514.1 - 1.7e-10 40.3 1.9 2.5e-10 39.8 0.1 2.3 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain HALZ PF02183.13 EXF80515.1 - 0.0083 15.8 3.7 0.019 14.6 0.9 2.5 2 0 0 2 2 2 1 Homeobox associated leucine zipper zf-Di19 PF05605.7 EXF80515.1 - 0.0099 15.9 0.1 0.023 14.8 0.0 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-ribbon_3 PF13248.1 EXF80515.1 - 0.1 11.8 0.2 0.19 10.9 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2HC_2 PF13913.1 EXF80515.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 zinc-finger of a C2HC-type zf-C2H2 PF00096.21 EXF80515.1 - 0.14 12.5 0.1 0.29 11.5 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-Nse PF11789.3 EXF80516.1 - 1.7e-19 69.0 0.1 7e-19 67.0 0.0 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 EXF80516.1 - 0.00013 21.8 0.0 0.00038 20.3 0.0 1.6 1 1 0 1 1 1 1 U-box domain zf-RING_UBOX PF13445.1 EXF80516.1 - 0.00037 20.1 0.2 0.001 18.7 0.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EXF80516.1 - 0.019 14.8 0.1 0.098 12.5 0.0 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EXF80516.1 - 0.023 14.5 0.2 0.041 13.6 0.1 1.4 1 0 0 1 1 1 0 Ring finger domain zf-rbx1 PF12678.2 EXF80516.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger DUF4440 PF14534.1 EXF80516.1 - 0.17 12.0 1.4 20 5.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) zf-MIZ PF02891.15 EXF80516.1 - 0.32 10.5 1.1 0.44 10.1 0.2 1.7 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Hexokinase_2 PF03727.11 EXF80517.1 - 3.5e-36 124.6 0.0 3.1e-28 98.6 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EXF80517.1 - 1.1e-28 99.9 0.0 1.6e-28 99.4 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Glucosamine_iso PF01182.15 EXF80518.1 - 4e-24 85.4 0.0 7e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase DUF3464 PF11947.3 EXF80518.1 - 0.0059 16.0 4.5 0.92 8.9 0.5 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3464) NDT80_PhoG PF05224.7 EXF80519.1 - 2.8e-32 112.2 0.0 4.5e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 NDT80 / PhoG like DNA-binding family Amidohydro_4 PF13147.1 EXF80519.1 - 6e-12 46.1 0.7 2.3e-11 44.2 0.5 1.9 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EXF80519.1 - 5e-06 25.9 0.0 1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 EXF80519.1 - 6.4e-06 26.0 0.3 7.4e-05 22.5 0.2 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EXF80519.1 - 0.0024 17.6 0.0 0.0081 15.9 0.0 1.9 1 0 0 1 1 1 1 Amidohydrolase DSHCT PF08148.7 EXF80519.1 - 0.25 10.5 0.0 0.46 9.7 0.0 1.3 1 0 0 1 1 1 0 DSHCT (NUC185) domain Glyco_hydro_3 PF00933.16 EXF80520.1 - 4.4e-55 186.7 0.0 7.4e-55 186.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF80520.1 - 0.00029 20.4 0.0 0.00059 19.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Innate_immun PF12782.2 EXF80520.1 - 1.9 7.6 8.0 3 6.9 5.5 1.2 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family Glyco_hydro_31 PF01055.21 EXF80521.1 - 1.5e-116 389.8 0.6 1.9e-116 389.5 0.4 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EXF80521.1 - 2.1e-15 56.3 0.2 2.3e-14 52.9 0.0 2.7 2 0 0 2 2 2 1 Galactose mutarotase-like Glyco_hydro_3 PF00933.16 EXF80522.1 - 5.1e-69 232.5 0.0 7.8e-69 231.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF80522.1 - 2.3e-59 200.6 0.1 3.5e-59 200.0 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF80522.1 - 5.4e-23 80.7 0.3 1.2e-22 79.5 0.2 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.6 EXF80522.1 - 0.064 13.3 0.2 0.16 11.9 0.2 1.6 1 0 0 1 1 1 0 CARDB Sugar-bind PF04198.8 EXF80522.1 - 0.13 11.1 0.0 0.25 10.1 0.0 1.4 1 0 0 1 1 1 0 Putative sugar-binding domain CytochromB561_N PF09786.4 EXF80523.1 - 1.8 6.9 4.3 2.3 6.5 3.0 1.2 1 0 0 1 1 1 0 Cytochrome B561, N terminal N2227 PF07942.7 EXF80524.1 - 2.9e-95 318.3 0.0 1.9e-93 312.3 0.0 2.1 1 1 0 1 1 1 1 N2227-like protein Methyltransf_23 PF13489.1 EXF80524.1 - 9.4e-05 22.1 0.0 0.00018 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF80524.1 - 0.0061 17.0 0.0 0.02 15.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF80524.1 - 0.022 15.2 0.0 0.05 14.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 EXF80525.1 - 8.3e-26 90.8 3.7 1.2e-25 90.3 2.6 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF80525.1 - 1e-22 81.1 0.0 1.6e-22 80.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF80525.1 - 9.9e-13 48.1 0.7 1.7e-12 47.3 0.5 1.3 1 1 0 1 1 1 1 KR domain PemK PF02452.12 EXF80526.1 - 0.042 14.0 0.0 0.097 12.8 0.0 1.5 1 1 0 1 1 1 0 PemK-like protein Syntaxin PF00804.20 EXF80527.1 - 0.14 12.3 2.2 7.5 6.7 0.4 2.7 2 0 0 2 2 2 0 Syntaxin DUF848 PF05852.6 EXF80527.1 - 1.8 8.4 6.1 0.77 9.6 0.6 2.8 3 0 0 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) DUF1682 PF07946.9 EXF80530.1 - 3.6 6.3 6.2 5.1 5.8 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) AAR2 PF05282.6 EXF80531.1 - 1.7e-52 178.5 0.0 2.6e-52 177.9 0.0 1.1 1 0 0 1 1 1 1 AAR2 protein DEAD PF00270.24 EXF80532.1 - 4e-46 156.5 0.0 1.7e-44 151.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF80532.1 - 1.1e-27 95.7 0.0 2.1e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EXF80532.1 - 0.00019 21.3 0.0 0.00061 19.6 0.0 1.9 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DUF1253 PF06862.7 EXF80532.1 - 0.00098 17.6 0.0 0.074 11.4 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF1253) Helicase_C_2 PF13307.1 EXF80532.1 - 0.0017 18.3 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 Helicase C-terminal domain DUF2443 PF10398.4 EXF80532.1 - 0.058 13.2 0.4 0.13 12.0 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) Glyoxalase_3 PF13468.1 EXF80532.1 - 0.085 12.7 0.0 0.21 11.4 0.0 1.6 2 0 0 2 2 2 0 Glyoxalase-like domain Phos_pyr_kin PF08543.7 EXF80533.1 - 2.2e-85 285.8 1.0 3.8e-85 285.0 0.7 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase TENA_THI-4 PF03070.11 EXF80533.1 - 5.2e-36 124.3 0.2 1.8e-17 63.8 0.0 2.2 1 1 1 2 2 2 2 TENA/THI-4/PQQC family PfkB PF00294.19 EXF80533.1 - 1.4e-10 40.7 0.3 2.3e-10 40.0 0.2 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase RICTOR_N PF14664.1 EXF80534.1 - 1.2e-138 461.7 7.1 1.5e-137 458.1 3.1 2.3 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EXF80534.1 - 5.4e-86 287.2 0.6 2.7e-84 281.7 0.0 3.4 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EXF80534.1 - 2.6e-40 136.9 0.2 4.1e-38 129.8 0.0 2.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EXF80534.1 - 1.2e-28 98.8 3.2 3.6e-27 94.0 0.1 4.1 6 0 0 6 6 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HR1 PF02185.11 EXF80534.1 - 2.1e-12 46.5 8.7 2.8e-12 46.1 4.1 2.4 2 0 0 2 2 2 1 Hr1 repeat HEAT_2 PF13646.1 EXF80534.1 - 1e-05 25.6 2.2 0.42 10.9 0.0 5.2 5 1 1 6 6 6 2 HEAT repeats Uds1 PF15456.1 EXF80534.1 - 0.0032 17.4 5.0 0.011 15.6 3.5 1.9 1 0 0 1 1 1 1 Up-regulated During Septation IncA PF04156.9 EXF80534.1 - 0.028 14.0 2.0 0.075 12.6 1.4 1.6 1 0 0 1 1 1 0 IncA protein DUF2443 PF10398.4 EXF80534.1 - 0.06 13.1 0.9 0.2 11.4 0.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2443) zf-C4H2 PF10146.4 EXF80534.1 - 1.3 9.0 9.2 1.6 8.6 1.8 3.2 3 0 0 3 3 3 0 Zinc finger-containing protein DUF883 PF05957.8 EXF80534.1 - 9 6.7 7.7 33 4.9 2.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) Uricase PF01014.13 EXF80535.1 - 4.1e-83 276.3 0.6 1.5e-44 151.4 0.3 2.0 2 0 0 2 2 2 2 Uricase Ribosomal_L13 PF00572.13 EXF80536.1 - 2.1e-38 131.2 0.0 2.8e-38 130.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L13 HMA PF00403.21 EXF80537.1 - 9.8e-12 44.8 0.0 1.6e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Heavy-metal-associated domain Sod_Cu PF00080.15 EXF80537.1 - 7.5e-11 42.3 0.0 1.2e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) TPR_11 PF13414.1 EXF80538.1 - 2e-21 75.3 8.8 1.7e-11 43.5 0.1 3.3 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 EXF80538.1 - 1.1e-18 65.9 6.4 5.8e-09 35.1 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.12 EXF80538.1 - 2e-16 58.4 5.3 1.1e-06 28.0 0.0 4.6 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.1 EXF80538.1 - 1.6e-14 53.5 0.2 3.7e-08 33.1 0.0 2.7 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.1 EXF80538.1 - 1.4e-12 46.4 2.3 7.5e-06 25.3 0.0 4.5 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.1 EXF80538.1 - 4.1e-09 35.5 0.2 6.7e-07 28.6 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EXF80538.1 - 1.1e-08 34.9 0.2 0.09 13.2 0.0 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat PB1 PF00564.19 EXF80538.1 - 1.8e-07 30.6 0.1 3.4e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TPR_17 PF13431.1 EXF80538.1 - 3e-07 30.0 0.2 0.0028 17.7 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EXF80538.1 - 1.4e-05 25.5 0.3 0.00087 19.8 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EXF80538.1 - 2.5e-05 24.0 0.2 0.61 9.9 0.0 3.1 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EXF80538.1 - 0.00052 20.4 0.1 0.022 15.3 0.0 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EXF80538.1 - 0.007 16.4 1.9 0.015 15.4 0.1 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EXF80538.1 - 0.018 15.3 0.1 0.16 12.3 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3808 PF10300.4 EXF80538.1 - 0.067 11.7 0.0 0.11 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) TPR_4 PF07721.9 EXF80538.1 - 0.074 13.5 0.4 36 5.1 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EXF80538.1 - 0.13 12.2 0.1 6 6.9 0.0 3.4 3 1 1 4 4 4 0 Tetratricopeptide repeat Ribosomal_S21 PF01165.15 EXF80538.1 - 0.7 9.3 0.0 0.7 9.3 0.0 2.9 5 0 0 5 5 4 0 Ribosomal protein S21 tRNA-synt_1c PF00749.16 EXF80539.1 - 8.2e-94 313.7 0.0 1.1e-93 313.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain DnaJ PF00226.26 EXF80540.1 - 7.6e-24 83.2 5.1 1.4e-23 82.3 3.5 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EXF80540.1 - 2.4e-22 78.6 0.1 5.5e-19 67.8 0.0 3.1 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EXF80540.1 - 4.8e-12 45.7 21.4 8.7e-12 44.9 14.8 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EXF80540.1 - 0.11 12.1 10.4 1.2 8.8 2.4 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-CHY PF05495.7 EXF80540.1 - 0.64 10.2 10.1 1.2 9.3 0.6 2.3 2 0 0 2 2 2 0 CHY zinc finger DUF1356 PF07092.7 EXF80540.1 - 4.8 6.3 6.2 5.7 6.0 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1356) Ribosomal_L32e PF01655.13 EXF80541.1 - 6.4e-49 164.5 1.6 8.6e-49 164.1 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 SH3_1 PF00018.23 EXF80543.1 - 1.9e-05 23.9 0.0 4.2e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EXF80543.1 - 0.0081 15.7 0.0 0.017 14.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Bac_rhamnosid PF05592.6 EXF80544.1 - 7.3e-29 100.3 0.6 2.5e-26 92.0 0.5 3.2 3 1 0 3 3 3 2 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 EXF80544.1 - 7.7e-07 28.1 0.3 1.3e-06 27.4 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function, DUF608 GDE_C PF06202.9 EXF80544.1 - 3.8e-06 25.8 0.0 5.6e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Colipase PF01114.13 EXF80545.1 - 0.0095 15.3 2.0 0.018 14.5 1.4 1.5 1 0 0 1 1 1 1 Colipase, N-terminal domain Aminotran_1_2 PF00155.16 EXF80546.1 - 3e-60 204.0 0.0 4e-60 203.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EXF80546.1 - 0.076 12.1 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Beta-eliminating lyase AMP-binding PF00501.23 EXF80547.1 - 1e-48 165.7 0.0 1.3e-48 165.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EXF80547.1 - 2.1e-05 25.3 0.3 7.3e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ELFV_dehydrog PF00208.16 EXF80548.1 - 2.4e-59 200.8 0.0 4e-59 200.1 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EXF80548.1 - 9.4e-20 69.7 0.1 2.5e-14 51.7 0.0 2.7 2 1 1 3 3 3 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EXF80548.1 - 0.00096 18.7 0.0 0.0036 16.8 0.0 1.9 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain DUF2666 PF10869.3 EXF80548.1 - 0.1 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2666) Aldose_epim PF01263.15 EXF80550.1 - 1.6e-49 168.6 0.5 2.2e-49 168.1 0.3 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Lsr2 PF11774.3 EXF80550.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 Lsr2 DUF1939 PF09154.5 EXF80550.1 - 0.34 10.8 4.6 5.7 6.9 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1939) Abhydrolase_6 PF12697.2 EXF80552.1 - 1.6e-16 60.9 0.5 2.3e-16 60.3 0.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF80552.1 - 1.1e-06 28.4 0.1 2.9e-06 27.1 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF80552.1 - 0.00093 18.8 0.0 0.0016 18.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold TAF4 PF05236.9 EXF80553.1 - 2.4e-07 30.2 11.5 8.2e-06 25.2 7.9 3.1 2 1 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family CPSF73-100_C PF11718.3 EXF80554.1 - 3.7e-73 245.4 0.0 2.8e-72 242.5 0.0 2.0 2 0 0 2 2 2 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EXF80554.1 - 1.8e-31 108.6 0.0 3.4e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EXF80554.1 - 1.2e-13 51.1 0.5 1.2e-13 51.1 0.4 1.9 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EXF80554.1 - 8.1e-13 48.3 0.6 1.6e-12 47.4 0.4 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EXF80554.1 - 5.1e-07 29.4 0.1 1e-06 28.4 0.1 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EXF80554.1 - 2.8e-06 27.1 0.8 8.3e-06 25.5 0.1 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain V_ATPase_I PF01496.14 EXF80555.1 - 1.5e-297 988.6 0.0 1.8e-297 988.4 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ERM PF00769.14 EXF80555.1 - 0.08 12.4 1.3 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF1515 PF07439.6 EXF80555.1 - 0.13 12.0 0.6 0.59 9.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) DUF3552 PF12072.3 EXF80555.1 - 0.35 10.0 3.5 3 6.9 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3552) Rootletin PF15035.1 EXF80555.1 - 1.3 8.9 7.2 2.5 8.0 0.7 2.2 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Mod_r PF07200.8 EXF80555.1 - 1.6 8.6 6.9 2.3 8.1 0.5 2.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Filament PF00038.16 EXF80555.1 - 4.7 6.5 9.4 0.96 8.8 0.7 2.3 2 1 0 2 2 2 0 Intermediate filament protein DivIC PF04977.10 EXF80555.1 - 6.8 6.2 9.0 0.3 10.5 0.3 2.9 3 0 0 3 3 3 0 Septum formation initiator CHD5 PF04420.9 EXF80556.1 - 3.3e-53 179.6 1.3 4.5e-53 179.2 0.9 1.2 1 0 0 1 1 1 1 CHD5-like protein DUF747 PF05346.6 EXF80556.1 - 0.025 13.6 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic membrane protein family Peptidase_S49_N PF08496.5 EXF80556.1 - 0.1 12.4 1.0 0.2 11.4 0.2 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Alpha_adaptin_C PF02296.11 EXF80556.1 - 0.11 12.4 0.5 0.2 11.6 0.3 1.3 1 0 0 1 1 1 0 Alpha adaptin AP2, C-terminal domain PPTA PF01239.17 EXF80557.1 - 0.0083 15.4 20.2 0.032 13.5 0.6 4.3 5 0 0 5 5 5 2 Protein prenyltransferase alpha subunit repeat Asp PF00026.18 EXF80558.1 - 6.8e-66 222.6 6.2 8.9e-66 222.2 4.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EXF80558.1 - 5e-08 33.0 2.6 5.4e-08 32.9 0.2 2.1 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EXF80558.1 - 3.3e-05 24.2 0.1 0.0029 18.0 0.0 2.9 2 0 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.1 EXF80558.1 - 0.068 12.7 0.0 0.21 11.1 0.0 1.9 1 1 1 2 2 2 0 Xylanase inhibitor C-terminal Aa_trans PF01490.13 EXF80559.1 - 9e-73 245.0 35.3 1e-72 244.8 24.5 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Fungal_trans PF04082.13 EXF80560.1 - 2.3e-24 85.6 0.0 3.3e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF80560.1 - 0.00011 21.9 8.1 0.00018 21.3 5.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Amidase PF01425.16 EXF80561.1 - 5.4e-86 289.1 0.0 9.1e-86 288.4 0.0 1.3 1 0 0 1 1 1 1 Amidase AHS2 PF02626.10 EXF80561.1 - 8.9e-84 280.9 0.0 1.4e-83 280.3 0.0 1.3 1 0 0 1 1 1 1 Allophanate hydrolase subunit 2 CPSase_L_D2 PF02786.12 EXF80561.1 - 6.1e-65 218.4 0.1 1e-64 217.6 0.1 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain AHS1 PF02682.11 EXF80561.1 - 2.9e-38 131.3 0.0 5.5e-38 130.4 0.0 1.4 1 0 0 1 1 1 1 Allophanate hydrolase subunit 1 CPSase_L_chain PF00289.17 EXF80561.1 - 2.1e-36 124.3 0.1 4.8e-36 123.2 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EXF80561.1 - 2.9e-33 114.0 0.0 8.5e-33 112.5 0.0 1.9 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EXF80561.1 - 2.7e-14 53.3 0.1 5.8e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EXF80561.1 - 2.2e-11 43.2 0.9 5.2e-11 42.0 0.6 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EXF80561.1 - 2.3e-11 43.0 0.0 3.1e-10 39.3 0.0 2.3 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EXF80561.1 - 3.8e-10 39.4 0.0 6.4e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.1 EXF80561.1 - 5.9e-06 25.8 0.0 0.15 11.7 0.1 2.9 2 1 1 3 3 3 2 Biotin-lipoyl like RimK PF08443.6 EXF80561.1 - 0.00036 20.0 0.0 0.00067 19.1 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 EXF80561.1 - 0.00081 18.7 0.1 0.0023 17.2 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EXF80561.1 - 0.01 15.7 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain GCV_H PF01597.14 EXF80561.1 - 0.05 13.2 0.2 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein DUF2118 PF09891.4 EXF80561.1 - 0.28 10.8 0.0 0.63 9.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) C2 PF00168.25 EXF80563.1 - 3.2e-20 71.7 0.0 8.9e-14 51.1 0.0 2.6 2 0 0 2 2 2 2 C2 domain Oxidored_FMN PF00724.15 EXF80564.1 - 1.2e-69 234.9 0.0 1.5e-69 234.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EXF80564.1 - 0.17 10.6 0.0 0.34 9.6 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Plant_NMP1 PF06694.6 EXF80564.1 - 0.17 10.7 0.0 0.54 9.1 0.0 1.7 2 0 0 2 2 2 0 Plant nuclear matrix protein 1 (NMP1) DAO PF01266.19 EXF80565.1 - 8e-44 149.9 0.1 9.2e-44 149.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EXF80565.1 - 5.3e-05 23.0 0.1 0.1 12.3 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EXF80565.1 - 7.4e-05 22.8 0.0 0.031 14.3 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EXF80565.1 - 0.0013 18.7 0.0 0.0034 17.3 0.0 1.7 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_8 PF13450.1 EXF80565.1 - 0.0049 16.8 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF80565.1 - 0.0055 16.5 0.0 1.6 8.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF80565.1 - 0.012 14.5 0.2 0.05 12.4 0.0 1.9 2 0 0 2 2 2 0 FAD binding domain Saccharop_dh PF03435.13 EXF80565.1 - 0.015 14.2 0.1 0.024 13.6 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Trp_halogenase PF04820.9 EXF80565.1 - 0.05 12.2 0.3 4.7 5.7 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase ThiF PF00899.16 EXF80565.1 - 0.095 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 ThiF family ApbA PF02558.11 EXF80565.1 - 0.12 11.7 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Sulfatase PF00884.18 EXF80566.1 - 1.9e-59 201.4 0.0 2.7e-59 200.8 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Sulfatase_C PF14707.1 EXF80566.1 - 6.5e-05 23.2 0.0 0.00015 22.0 0.0 1.6 1 0 0 1 1 1 1 C-terminal region of aryl-sulfatase Phosphodiest PF01663.17 EXF80566.1 - 0.00061 19.2 0.0 0.069 12.4 0.0 2.2 2 0 0 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase VSP PF03302.8 EXF80566.1 - 0.0039 15.8 2.3 0.0039 15.8 1.6 1.5 2 0 0 2 2 2 1 Giardia variant-specific surface protein IncA PF04156.9 EXF80566.1 - 0.0079 15.8 0.7 0.012 15.1 0.5 1.2 1 0 0 1 1 1 1 IncA protein Adeno_E3_CR2 PF02439.10 EXF80566.1 - 0.16 11.4 0.2 0.35 10.4 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 NUC173 PF08161.7 EXF80567.1 - 8.7e-78 260.2 3.8 1.4e-76 256.2 0.1 3.1 4 0 0 4 4 4 2 NUC173 domain DinB_2 PF12867.2 EXF80567.1 - 0.0028 17.9 0.1 0.024 14.9 0.0 2.6 3 0 0 3 3 3 1 DinB superfamily Rsbr_N PF08678.5 EXF80567.1 - 0.03 14.2 0.2 7.6 6.4 0.0 3.1 3 0 0 3 3 3 0 Rsbr N terminal HEAT PF02985.17 EXF80567.1 - 0.098 12.7 1.8 2.2 8.6 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat V-SNARE PF05008.10 EXF80568.1 - 4e-20 71.7 1.3 4e-20 71.7 0.9 1.7 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EXF80568.1 - 2.1e-19 69.3 1.9 2.1e-19 69.3 1.3 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EXF80568.1 - 0.016 14.9 0.9 0.04 13.6 0.2 2.0 2 1 1 3 3 3 0 Sec20 Spectrin PF00435.16 EXF80568.1 - 0.074 13.3 2.1 0.22 11.8 0.2 2.4 2 1 1 3 3 3 0 Spectrin repeat Fusion_gly PF00523.13 EXF80568.1 - 0.13 10.2 2.5 0.77 7.7 0.4 2.1 2 0 0 2 2 2 0 Fusion glycoprotein F0 YvbH_ext PF11724.3 EXF80568.1 - 0.15 11.7 0.1 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 YvbH-like oligomerisation region OppC_N PF12911.2 EXF80568.1 - 1.5 8.2 4.3 0.51 9.7 1.1 1.6 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C PRA1 PF03208.14 EXF80569.1 - 9.1e-05 21.8 2.1 0.00016 21.0 1.4 1.3 1 0 0 1 1 1 1 PRA1 family protein DUF755 PF05501.6 EXF80569.1 - 5.7 7.0 13.1 1.9 8.5 5.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF755) Amino_oxidase PF01593.19 EXF80570.1 - 4.1e-14 52.5 0.1 0.00016 20.8 0.0 3.1 3 0 0 3 3 3 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EXF80570.1 - 1.7e-11 44.0 0.1 4e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EXF80570.1 - 1.1e-08 35.3 0.1 0.0003 20.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF80570.1 - 3.7e-07 29.3 1.8 0.00093 18.1 0.1 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EXF80570.1 - 1.4e-05 24.9 0.6 0.03 14.0 0.1 2.8 2 1 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EXF80570.1 - 2.5e-05 24.2 0.0 0.0045 16.9 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF80570.1 - 0.00011 20.8 0.1 0.061 11.7 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox PF00070.22 EXF80570.1 - 0.0096 16.3 0.2 0.7 10.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF80570.1 - 0.013 14.3 0.1 0.022 13.6 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Thi4 PF01946.12 EXF80570.1 - 0.12 11.4 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family CtaG_Cox11 PF04442.9 EXF80571.1 - 6.8e-57 191.5 0.0 1.1e-56 190.8 0.0 1.4 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 KOW PF00467.24 EXF80572.1 - 8.5e-08 31.6 1.9 2e-07 30.4 1.3 1.6 1 0 0 1 1 1 1 KOW motif DUF1223 PF06764.6 EXF80572.1 - 0.13 12.0 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1223) DUF2950 PF11453.3 EXF80573.1 - 0.088 11.7 0.3 0.25 10.3 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2950) Col_cuticle_N PF01484.12 EXF80575.1 - 1.9 8.2 4.3 3.8 7.2 3.0 1.5 1 0 0 1 1 1 0 Nematode cuticle collagen N-terminal domain VSP PF03302.8 EXF80576.1 - 7.4e-06 24.8 0.5 1.2e-05 24.2 0.1 1.5 2 0 0 2 2 2 1 Giardia variant-specific surface protein SKG6 PF08693.5 EXF80576.1 - 0.00046 19.4 0.2 0.00083 18.6 0.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EXF80576.1 - 0.0051 16.3 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) GPI-anchored PF10342.4 EXF80576.1 - 0.011 16.1 1.0 0.02 15.3 0.7 1.4 1 0 0 1 1 1 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family Herpes_gE PF02480.11 EXF80576.1 - 0.033 12.4 0.0 0.054 11.7 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF347 PF03988.7 EXF80576.1 - 0.061 13.2 0.4 0.12 12.3 0.3 1.5 1 0 0 1 1 1 0 Repeat of Unknown Function (DUF347) Myc_target_1 PF15179.1 EXF80576.1 - 0.12 11.8 1.8 0.22 11.1 1.3 1.4 1 0 0 1 1 1 0 Myc target protein 1 Ala_racemase_N PF01168.15 EXF80577.1 - 3.2e-38 131.4 0.1 3.9e-38 131.2 0.1 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Zn_clus PF00172.13 EXF80578.1 - 5.1e-08 32.6 12.2 8.2e-08 32.0 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain HMGL-like PF00682.14 EXF80580.1 - 4.8e-38 131.1 0.0 8.8e-38 130.2 0.0 1.4 1 1 0 1 1 1 1 HMGL-like ATP-synt_ab PF00006.20 EXF80581.1 - 2.1e-59 200.6 0.0 3.3e-59 199.9 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EXF80581.1 - 1.3e-17 64.3 0.7 2.4e-17 63.4 0.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EXF80581.1 - 1.2e-13 51.0 0.9 2.6e-13 49.9 0.6 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EXF80581.1 - 3.4e-05 23.6 0.4 6.8e-05 22.6 0.3 1.5 1 0 0 1 1 1 1 HAS barrel domain DUF561 PF04481.7 EXF80581.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF561) P16-Arc PF04699.9 EXF80582.1 - 1.8e-53 180.6 0.0 2.1e-53 180.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) DUF2605 PF10792.4 EXF80582.1 - 0.08 12.6 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) Methyltransf_11 PF08241.7 EXF80583.1 - 2.3e-09 37.5 0.0 6.5e-09 36.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF80583.1 - 5.5e-09 35.9 0.0 1.5e-08 34.4 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF80583.1 - 9.2e-07 29.2 0.0 1.7e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF80583.1 - 0.0005 19.6 0.0 0.0012 18.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Adaptin_N PF01602.15 EXF80584.1 - 2.1e-122 409.1 10.3 2.5e-122 408.8 7.2 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EXF80584.1 - 1.8e-46 156.7 0.0 6.4e-46 154.9 0.0 2.0 2 0 0 2 2 2 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EXF80584.1 - 1.3e-18 67.3 0.0 2.5e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Adaptin C-terminal domain zf-C2H2_4 PF13894.1 EXF80585.1 - 9.5 6.8 30.1 0.24 11.8 4.4 4.4 4 1 0 4 4 4 0 C2H2-type zinc finger DUF629 PF04780.7 EXF80586.1 - 0.00029 19.4 5.2 0.00062 18.3 1.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF629) zf-C2H2_2 PF12756.2 EXF80586.1 - 0.0092 16.0 2.4 0.029 14.4 1.6 1.8 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EXF80586.1 - 0.016 15.4 0.6 0.016 15.4 0.4 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type Med19 PF10278.4 EXF80586.1 - 0.13 11.9 4.5 0.27 10.9 3.1 1.5 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 zf-C2H2_4 PF13894.1 EXF80586.1 - 0.17 12.2 11.4 0.27 11.6 0.6 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger zf-met PF12874.2 EXF80586.1 - 0.33 11.2 5.4 6.2 7.1 0.4 2.7 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Paramyxo_ncap PF00973.14 EXF80586.1 - 0.94 8.0 4.2 1.7 7.2 2.9 1.3 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein zf-Di19 PF05605.7 EXF80588.1 - 0.0004 20.4 4.8 0.4 10.8 0.1 3.4 3 0 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.1 EXF80588.1 - 0.0038 17.4 13.8 0.21 11.9 0.2 4.6 3 1 0 3 3 3 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EXF80588.1 - 0.0039 17.2 6.3 0.11 12.5 0.0 3.5 1 1 2 3 3 3 1 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.21 EXF80588.1 - 0.01 16.1 12.8 2 8.9 0.3 4.7 4 0 0 4 4 4 0 Zinc finger, C2H2 type BIR PF00653.16 EXF80588.1 - 0.025 14.9 0.6 1.8 9.0 0.2 2.7 2 0 0 2 2 2 0 Inhibitor of Apoptosis domain zf-H2C2_2 PF13465.1 EXF80588.1 - 0.046 14.0 5.7 9.8 6.6 0.1 3.8 3 0 0 3 3 3 0 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EXF80588.1 - 0.23 11.6 0.0 0.23 11.6 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EXF80588.1 - 0.36 11.1 1.7 0.6 10.3 0.1 2.3 2 0 0 2 2 2 0 Zinc-finger of C2H2 type NPP1 PF05630.6 EXF80590.1 - 7.9e-61 205.4 0.1 9.1e-61 205.2 0.0 1.0 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) Fungal_trans PF04082.13 EXF80591.1 - 1.3e-11 43.8 0.5 2.6e-11 42.8 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF80591.1 - 5.6e-08 32.5 8.2 1.3e-07 31.4 5.7 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Phosphoesterase PF04185.9 EXF80592.1 - 3.7e-19 69.1 0.5 1.1e-18 67.6 0.4 1.7 1 1 0 1 1 1 1 Phosphoesterase family Lumazine_bd PF12870.2 EXF80593.1 - 7.8e-05 22.6 0.4 0.00013 21.9 0.3 1.3 1 0 0 1 1 1 1 Lumazine-binding domain PepSY_TM PF03929.11 EXF80593.1 - 0.41 11.1 5.3 0.47 10.9 0.5 3.4 2 0 0 2 2 2 0 PepSY-associated TM helix ApbA_C PF08546.6 EXF80594.1 - 2.8e-25 88.7 0.0 4.4e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EXF80594.1 - 4.7e-24 84.5 0.0 6.7e-24 84.0 0.0 1.2 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA ThiF PF00899.16 EXF80594.1 - 0.0036 17.1 0.4 0.0036 17.1 0.3 2.4 3 0 0 3 3 3 1 ThiF family IlvN PF07991.7 EXF80594.1 - 0.012 14.9 0.1 0.5 9.7 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain DUF2470 PF10615.4 EXF80595.1 - 2.9e-18 65.8 0.0 4e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) COesterase PF00135.23 EXF80596.1 - 1.9e-87 294.2 0.2 1.3e-80 271.6 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF80596.1 - 4.9e-13 49.1 0.0 7.7e-13 48.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF80596.1 - 0.0041 16.8 0.0 0.0083 15.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family ADH_N PF08240.7 EXF80598.1 - 3.6e-16 58.8 0.3 1.3e-15 57.0 0.2 2.0 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF80598.1 - 8.3e-10 38.3 0.0 1.9e-09 37.1 0.0 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EXF80598.1 - 0.0028 17.2 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Shikimate_DH PF01488.15 EXF80598.1 - 0.013 15.6 0.0 0.077 13.0 0.0 2.0 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 EXF80598.1 - 0.03 12.8 0.0 0.038 12.4 0.0 1.1 1 0 0 1 1 1 0 HI0933-like protein DAO PF01266.19 EXF80598.1 - 0.053 12.4 0.2 0.08 11.8 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF80598.1 - 0.071 11.9 0.1 0.071 11.9 0.0 1.8 2 0 0 2 2 2 0 FAD binding domain FAD_binding_3 PF01494.14 EXF80598.1 - 0.1 11.6 0.1 0.15 11.1 0.1 1.1 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EXF80598.1 - 0.12 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase COesterase PF00135.23 EXF80599.1 - 1.5e-83 281.3 0.0 3.3e-79 267.0 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF80599.1 - 6.8e-14 51.9 0.2 1.1e-13 51.3 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF80599.1 - 0.0046 16.7 0.2 0.0077 15.9 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EXF80599.1 - 0.0081 15.4 0.1 0.016 14.4 0.1 1.5 1 0 0 1 1 1 1 Esterase PHB depolymerase Bac_rhamnosid_N PF08531.5 EXF80599.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.2 1 0 0 1 1 1 0 Alpha-L-rhamnosidase N-terminal domain Glyco_hydro_61 PF03443.9 EXF80602.1 - 3.9e-79 265.5 0.2 4.4e-79 265.3 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 NPCBM_assoc PF10633.4 EXF80602.1 - 0.0018 18.2 0.1 2.2 8.3 0.0 2.7 2 0 0 2 2 2 2 NPCBM-associated, NEW3 domain of alpha-galactosidase HrpF PF06266.7 EXF80602.1 - 0.008 16.2 0.1 0.52 10.4 0.0 2.3 2 0 0 2 2 2 1 HrpF protein CSD PF00313.17 EXF80602.1 - 0.086 12.6 0.0 0.18 11.6 0.0 1.5 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain Peptidase_M35 PF02102.10 EXF80603.1 - 4.1e-83 278.9 18.9 5e-83 278.7 13.1 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EXF80603.1 - 2.4e-08 34.6 2.4 4.4e-08 33.7 1.7 1.4 1 0 0 1 1 1 1 Lysine-specific metallo-endopeptidase COesterase PF00135.23 EXF80604.1 - 7.4e-83 279.0 2.4 1.4e-82 278.1 1.6 1.3 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF80604.1 - 2.3e-05 24.0 0.1 0.00016 21.3 0.0 2.1 1 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EXF80604.1 - 0.0043 16.2 0.4 0.0043 16.2 0.3 2.2 2 1 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EXF80604.1 - 0.056 13.2 0.4 0.25 11.0 0.1 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Glyco_hydro_47 PF01532.15 EXF80605.1 - 1e-129 433.1 0.0 1.7e-129 432.3 0.0 1.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Sulfotransfer_3 PF13469.1 EXF80607.1 - 0.00038 21.4 0.2 0.00076 20.4 0.1 1.6 1 1 1 2 2 2 1 Sulfotransferase family ketoacyl-synt PF00109.21 EXF80608.1 - 2.9e-72 243.1 0.0 6.4e-72 242.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EXF80608.1 - 3.5e-56 190.8 0.0 6e-56 190.0 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EXF80608.1 - 6.4e-54 182.3 0.0 2.2e-53 180.6 0.0 2.0 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EXF80608.1 - 7.3e-52 176.3 0.0 1.4e-51 175.4 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EXF80608.1 - 6.7e-40 136.7 0.1 2.3e-39 134.9 0.0 2.0 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EXF80608.1 - 6.6e-39 132.4 0.1 2.1e-38 130.8 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EXF80608.1 - 2.1e-21 76.2 0.0 1.1e-20 73.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N PF00107.21 EXF80608.1 - 1.7e-20 72.8 0.4 3.8e-19 68.5 0.0 3.4 4 0 0 4 4 4 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF80608.1 - 8.6e-15 55.7 0.0 1.6e-13 51.6 0.0 3.0 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EXF80608.1 - 1.2e-12 47.8 0.0 2.6e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF80608.1 - 2.6e-12 46.6 0.0 6.8e-12 45.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF80608.1 - 2.1e-11 44.4 0.0 3.5e-10 40.4 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF80608.1 - 7.5e-11 42.3 0.0 2.4e-10 40.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EXF80608.1 - 4.9e-07 29.9 0.0 2.2e-06 27.8 0.0 2.2 2 0 0 2 2 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 EXF80608.1 - 1.2e-06 28.2 0.1 3.7e-06 26.6 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_26 PF13659.1 EXF80608.1 - 1.7e-06 28.0 0.0 1.8e-05 24.7 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.18 EXF80608.1 - 2e-06 26.9 0.0 4.1e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.13 EXF80608.1 - 4.7e-05 22.6 0.0 0.00013 21.2 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF938 PF06080.7 EXF80608.1 - 5.1e-05 22.9 0.0 0.00014 21.4 0.0 1.7 2 0 0 2 2 1 1 Protein of unknown function (DUF938) Methyltransf_28 PF02636.12 EXF80608.1 - 0.017 14.5 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_16 PF10294.4 EXF80608.1 - 0.017 14.5 0.0 0.041 13.3 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase PsbP PF01789.11 EXF80608.1 - 0.055 12.9 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 PsbP Methyltransf_24 PF13578.1 EXF80608.1 - 0.058 14.2 0.0 0.19 12.6 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain DUF915 PF06028.6 EXF80608.1 - 0.079 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DREV PF05219.7 EXF80608.1 - 0.16 10.8 0.0 0.35 9.6 0.0 1.5 1 0 0 1 1 1 0 DREV methyltransferase RNF111_N PF15303.1 EXF80608.1 - 0.21 11.1 2.8 0.35 10.3 2.0 1.3 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus FAD_binding_4 PF01565.18 EXF80609.1 - 1e-21 76.8 0.3 6.1e-20 71.1 0.1 2.8 2 1 0 2 2 2 1 FAD binding domain BBE PF08031.7 EXF80609.1 - 3.1e-05 23.7 0.0 7.3e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 EXF80610.1 - 3e-62 210.6 0.0 3.7e-62 210.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CDI PF02234.14 EXF80610.1 - 0.035 13.8 0.2 0.094 12.5 0.2 1.7 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor p450 PF00067.17 EXF80611.1 - 3.1e-55 187.5 0.0 4.9e-55 186.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Clathrin_bdg PF15045.1 EXF80611.1 - 0.11 12.0 0.1 0.27 10.7 0.0 1.7 1 0 0 1 1 1 0 Clathrin-binding box of Aftiphilin, vesicle trafficking Aldedh PF00171.17 EXF80612.1 - 3.1e-188 625.8 0.4 3.5e-188 625.6 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EXF80612.1 - 0.086 11.5 0.2 0.22 10.2 0.1 1.6 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) HAMP PF00672.20 EXF80614.1 - 2e-47 159.2 22.5 1.4e-10 41.1 0.3 7.4 7 0 0 7 7 7 6 HAMP domain HATPase_c PF02518.21 EXF80614.1 - 2.4e-30 104.4 0.1 1.1e-29 102.4 0.0 2.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EXF80614.1 - 2.4e-28 98.3 0.8 5.1e-26 90.8 0.2 2.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EXF80614.1 - 8.9e-19 67.2 5.8 4e-18 65.1 0.4 4.2 3 0 0 3 3 3 1 His Kinase A (phospho-acceptor) domain DUF883 PF05957.8 EXF80614.1 - 0.049 14.0 15.3 1.2 9.6 0.3 6.0 5 2 2 7 7 7 0 Bacterial protein of unknown function (DUF883) NAAA-beta PF15508.1 EXF80614.1 - 0.072 13.4 2.7 7.6 6.9 0.1 5.1 3 2 2 5 5 5 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF948 PF06103.6 EXF80614.1 - 2.5 8.0 33.6 0.71 9.7 0.2 8.5 4 2 1 7 7 7 0 Bacterial protein of unknown function (DUF948) R3H PF01424.17 EXF80615.1 - 6e-14 51.4 0.2 1.1e-13 50.6 0.2 1.4 1 0 0 1 1 1 1 R3H domain zf-NF-X1 PF01422.12 EXF80615.1 - 2.9e-05 23.9 180.3 0.00077 19.3 7.5 13.1 12 1 0 12 12 12 7 NF-X1 type zinc finger Methyltransf_23 PF13489.1 EXF80616.1 - 5.9e-26 91.1 0.0 8e-26 90.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF80616.1 - 7.1e-11 41.9 0.0 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF80616.1 - 6.7e-10 39.5 0.0 3e-09 37.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF80616.1 - 1.4e-08 35.0 0.0 5.3e-08 33.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF80616.1 - 4.3e-08 33.5 0.0 7.7e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF80616.1 - 1.6e-05 25.1 0.0 3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EXF80616.1 - 0.0021 17.2 0.0 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EXF80616.1 - 0.0042 16.2 0.0 0.0061 15.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EXF80616.1 - 0.0099 15.9 0.0 0.018 15.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EXF80616.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein MTS PF05175.9 EXF80616.1 - 0.011 15.1 0.0 0.03 13.7 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 EXF80616.1 - 0.047 13.6 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EXF80616.1 - 0.048 13.1 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_23 PF13489.1 EXF80617.1 - 7.5e-19 68.0 0.0 1.3e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF80617.1 - 1.3e-11 45.0 0.0 4.9e-11 43.2 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF80617.1 - 5.8e-09 36.3 0.0 2.1e-08 34.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF80617.1 - 9.5e-09 35.0 0.0 3.7e-08 33.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF80617.1 - 6.2e-08 33.0 0.0 1.1e-07 32.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF80617.1 - 4.2e-05 23.8 0.0 9.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EXF80617.1 - 0.0037 17.2 0.0 0.0057 16.6 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_2 PF00891.13 EXF80617.1 - 0.017 14.3 0.1 0.082 12.0 0.1 1.9 1 1 0 1 1 1 0 O-methyltransferase Methyltransf_4 PF02390.12 EXF80617.1 - 0.023 13.7 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 EXF80617.1 - 0.026 14.5 0.0 0.12 12.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain CopK PF11525.3 EXF80617.1 - 0.049 13.2 0.0 0.095 12.3 0.0 1.4 1 0 0 1 1 1 0 Copper resistance protein K CheR PF01739.13 EXF80617.1 - 0.054 12.7 0.0 0.092 12.0 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Methyltransf_17 PF12692.2 EXF80617.1 - 0.12 12.0 0.0 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 S-adenosyl-L-methionine methyltransferase RTA1 PF04479.8 EXF80618.1 - 4.7e-22 78.5 0.4 7.6e-22 77.9 0.3 1.2 1 0 0 1 1 1 1 RTA1 like protein Abhydrolase_6 PF12697.2 EXF80619.1 - 1.4e-19 70.8 0.1 1.9e-19 70.4 0.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF80619.1 - 4.4e-12 45.9 0.1 6.6e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF80619.1 - 0.00024 20.7 0.2 0.06 12.8 0.0 2.5 2 1 1 3 3 3 2 alpha/beta hydrolase fold Ser_hydrolase PF06821.8 EXF80619.1 - 0.0093 15.5 0.0 0.17 11.4 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase DUF900 PF05990.7 EXF80619.1 - 0.046 13.0 0.0 0.07 12.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 EXF80619.1 - 0.06 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein TBCA PF02970.11 EXF80620.1 - 1e-17 63.9 4.7 1e-17 63.9 3.3 1.3 1 1 0 1 1 1 1 Tubulin binding cofactor A TAP42 PF04177.7 EXF80620.1 - 0.019 13.9 0.6 0.018 13.9 0.4 1.2 1 0 0 1 1 1 0 TAP42-like family Cytochrom_C552 PF02335.10 EXF80620.1 - 0.084 11.5 0.2 0.11 11.1 0.1 1.1 1 0 0 1 1 1 0 Cytochrome c552 ApoLp-III PF07464.6 EXF80620.1 - 0.085 12.8 3.3 0.092 12.7 2.3 1.2 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF816 PF05674.7 EXF80620.1 - 0.094 12.4 0.0 0.12 12.0 0.0 1.2 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF816) Angiomotin_C PF12240.3 EXF80620.1 - 0.23 10.9 3.3 0.16 11.4 0.6 1.7 2 0 0 2 2 2 0 Angiomotin C terminal DUF4404 PF14357.1 EXF80620.1 - 0.6 10.5 2.8 0.55 10.6 0.5 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4404) THOC7 PF05615.8 EXF80621.1 - 5.1e-36 124.0 2.1 5.1e-36 124.0 1.4 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 RTBV_P46 PF06216.6 EXF80621.1 - 0.011 14.6 2.4 0.011 14.6 1.7 2.0 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein DUF972 PF06156.8 EXF80621.1 - 0.059 13.7 9.9 0.76 10.1 0.7 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF972) Sec66 PF09802.4 EXF80621.1 - 0.061 12.7 10.3 0.31 10.4 1.8 2.1 2 0 0 2 2 2 0 Preprotein translocase subunit Sec66 Herpes_UL17 PF04559.7 EXF80621.1 - 0.57 8.7 5.9 0.1 11.1 1.7 1.5 2 0 0 2 2 2 0 Herpesvirus UL17 protein FUSC PF04632.7 EXF80621.1 - 0.59 8.4 3.7 0.76 8.1 2.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family zf-C4H2 PF10146.4 EXF80621.1 - 0.83 9.6 10.5 0.12 12.3 3.6 2.2 1 1 2 3 3 3 0 Zinc finger-containing protein zf-CCCH PF00642.19 EXF80622.1 - 6.1e-05 22.6 25.0 0.32 10.7 0.2 5.5 4 1 1 5 5 5 4 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Sel1 PF08238.7 EXF80623.1 - 5.8e-18 64.9 4.5 2.4e-05 24.8 0.3 3.6 3 0 0 3 3 3 3 Sel1 repeat TraC PF07820.7 EXF80623.1 - 0.03 14.4 0.1 0.03 14.4 0.1 2.1 2 0 0 2 2 2 0 TraC-like protein Atx10homo_assoc PF09759.4 EXF80624.1 - 3.5e-11 42.7 0.0 9.9e-11 41.2 0.0 1.7 2 0 0 2 2 2 1 Spinocerebellar ataxia type 10 protein domain tRNA-synt_1b PF00579.20 EXF80625.1 - 1e-58 198.8 0.0 1.3e-58 198.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) PNP_UDP_1 PF01048.15 EXF80626.1 - 7.3e-39 133.1 0.3 1e-38 132.6 0.2 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily Med13_C PF06333.7 EXF80627.1 - 3.7e-103 345.3 0.0 7.8e-103 344.2 0.0 1.6 2 0 0 2 2 2 1 Mediator complex subunit 13 C-terminal Med13_N PF11597.3 EXF80627.1 - 1e-32 113.3 0.0 1.9e-32 112.4 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 13 N-terminal NUC153 PF08159.7 EXF80628.1 - 1.7e-12 46.6 3.5 3.5e-12 45.6 2.4 1.6 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.27 EXF80628.1 - 0.00026 20.7 0.1 0.11 12.3 0.0 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat DUF2371 PF10177.4 EXF80629.1 - 0.026 14.4 0.3 0.042 13.7 0.1 1.4 1 1 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) TMEM210 PF15195.1 EXF80629.1 - 0.032 14.3 0.2 0.045 13.8 0.1 1.2 1 0 0 1 1 1 0 TMEM210 family DUF4448 PF14610.1 EXF80629.1 - 0.11 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Ribosomal_L33 PF00471.15 EXF80631.1 - 2.4e-07 30.8 0.0 3.1e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 Aminotran_1_2 PF00155.16 EXF80632.1 - 1.7e-38 132.5 0.0 2.3e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EXF80632.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase RPN7 PF10602.4 EXF80633.1 - 3.1e-56 189.5 0.5 3.1e-56 189.5 0.4 1.7 2 0 0 2 2 2 1 26S proteasome subunit RPN7 PCI PF01399.22 EXF80633.1 - 1.6e-15 57.3 0.0 3.6e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 PCI domain TPR_14 PF13428.1 EXF80633.1 - 0.23 12.1 4.0 0.92 10.3 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Pox_MCEL PF03291.11 EXF80634.1 - 5.6e-66 222.6 0.0 2.7e-45 154.6 0.0 2.4 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_12 PF08242.7 EXF80634.1 - 4.1e-09 36.7 0.1 0.0018 18.6 0.0 3.1 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.7 EXF80634.1 - 3.9e-08 33.6 0.0 2.7e-07 31.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF80634.1 - 1e-06 29.2 0.1 3.5e-06 27.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF80634.1 - 2.4e-06 27.3 0.0 5.2e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF80634.1 - 1.3e-05 25.4 0.0 4.3e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF80634.1 - 3.3e-05 23.5 0.0 0.00089 18.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EXF80634.1 - 0.00026 20.0 0.0 0.0004 19.4 0.0 1.2 1 0 0 1 1 1 1 NNMT/PNMT/TEMT family Methyltransf_26 PF13659.1 EXF80634.1 - 0.082 12.9 0.1 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_9 PF08003.6 EXF80634.1 - 0.14 10.8 0.0 0.32 9.6 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1698) DUF500 PF04366.7 EXF80639.1 - 2.1e-45 153.2 1.0 4.1e-45 152.3 0.3 1.7 2 0 0 2 2 2 1 Family of unknown function (DUF500) SH3_1 PF00018.23 EXF80639.1 - 1.1e-13 50.2 0.2 3.1e-13 48.8 0.0 1.8 2 0 0 2 2 2 1 SH3 domain SH3_2 PF07653.12 EXF80639.1 - 2.4e-12 46.1 0.0 5.6e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EXF80639.1 - 1e-11 44.2 0.0 1.9e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain Synaptobrevin PF00957.16 EXF80641.1 - 0.0013 18.2 0.8 0.01 15.3 0.3 2.0 1 1 1 2 2 2 1 Synaptobrevin UBN2_2 PF14227.1 EXF80641.1 - 0.036 13.6 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF4608 PF15381.1 EXF80641.1 - 0.055 13.6 0.2 0.072 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4608) ArfGap PF01412.13 EXF80642.1 - 1.1e-39 134.7 1.4 1.7e-39 134.2 1.0 1.3 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf 2-Hacid_dh_C PF02826.14 EXF80643.1 - 1.4e-52 177.4 0.1 2.3e-52 176.7 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EXF80643.1 - 1.3e-34 118.5 1.6 1.6e-34 118.2 0.4 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.20 EXF80643.1 - 0.00049 19.5 2.1 0.0013 18.1 0.0 2.6 3 0 0 3 3 3 1 ACT domain XdhC_C PF13478.1 EXF80643.1 - 0.037 14.3 0.0 0.076 13.3 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain 3HCDH_N PF02737.13 EXF80643.1 - 0.061 12.9 0.5 0.18 11.4 0.3 1.8 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EXF80643.1 - 0.076 12.5 1.2 0.21 11.1 0.5 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain DUF21 PF01595.15 EXF80644.1 - 2e-31 108.7 0.0 3.1e-31 108.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EXF80644.1 - 0.00012 21.8 0.4 0.088 12.6 0.0 2.7 2 0 0 2 2 2 2 CBS domain Lactonase PF10282.4 EXF80645.1 - 6e-18 65.0 0.0 7.8e-18 64.6 0.0 1.2 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller WD40 PF00400.27 EXF80645.1 - 0.055 13.3 0.0 8.1 6.5 0.0 4.0 5 0 0 5 5 5 0 WD domain, G-beta repeat Ank_2 PF12796.2 EXF80646.1 - 4.2e-21 75.0 0.3 2.9e-14 53.1 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EXF80646.1 - 8.2e-18 63.2 1.5 1.6e-07 30.7 0.0 4.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EXF80646.1 - 2.8e-11 42.5 0.6 0.0016 18.4 0.0 5.3 4 0 0 4 4 4 2 Ankyrin repeat AAA_16 PF13191.1 EXF80646.1 - 1.5e-10 41.3 0.5 5.7e-10 39.4 0.3 2.0 1 0 0 1 1 1 1 AAA ATPase domain Ank_4 PF13637.1 EXF80646.1 - 2.8e-10 40.4 0.5 2.1e-05 24.9 0.0 4.2 3 1 2 5 5 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF80646.1 - 1.2e-07 31.7 0.8 0.013 15.7 0.0 3.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) AAA_22 PF13401.1 EXF80646.1 - 3.3e-07 30.5 0.1 1e-06 28.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain NACHT PF05729.7 EXF80646.1 - 6.4e-05 22.6 0.3 0.00015 21.4 0.0 1.7 2 0 0 2 2 2 1 NACHT domain AAA_5 PF07728.9 EXF80646.1 - 0.00012 21.7 0.0 0.00049 19.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EXF80646.1 - 0.0002 21.5 0.0 0.00057 20.0 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EXF80646.1 - 0.0015 18.4 0.0 0.076 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EXF80646.1 - 0.007 15.2 0.0 0.027 13.3 0.0 1.8 2 0 0 2 2 2 1 NB-ARC domain AAA_29 PF13555.1 EXF80646.1 - 0.023 14.2 0.0 0.09 12.3 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_19 PF13245.1 EXF80646.1 - 0.027 14.2 0.0 0.062 13.0 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EXF80646.1 - 0.028 13.8 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_10 PF12846.2 EXF80646.1 - 0.034 13.5 0.0 0.11 11.8 0.0 1.8 1 1 0 1 1 1 0 AAA-like domain Arch_ATPase PF01637.13 EXF80646.1 - 0.068 12.8 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase ATP-synt_ab PF00006.20 EXF80646.1 - 0.17 11.3 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_17 PF13207.1 EXF80646.1 - 0.37 11.6 2.1 1.7 9.4 0.1 2.9 2 2 0 2 2 2 0 AAA domain ABC_membrane PF00664.18 EXF80647.1 - 7e-36 124.0 16.8 2.4e-23 82.9 2.9 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EXF80647.1 - 2.3e-34 118.6 0.0 1.2e-16 61.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EXF80647.1 - 2.3e-07 30.2 0.4 0.021 14.0 0.0 3.2 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EXF80647.1 - 5.2e-05 23.3 0.7 0.46 10.4 0.1 3.5 3 1 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EXF80647.1 - 0.00021 21.4 0.3 0.061 13.4 0.1 3.4 3 1 0 3 3 2 1 AAA domain AAA_16 PF13191.1 EXF80647.1 - 0.00098 19.1 0.2 0.02 14.9 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 EXF80647.1 - 0.0019 17.7 1.8 0.18 11.2 0.1 2.5 2 0 0 2 2 2 1 AAA-like domain Arch_ATPase PF01637.13 EXF80647.1 - 0.0032 17.2 0.0 0.0078 15.9 0.0 1.7 1 0 0 1 1 1 1 Archaeal ATPase AAA_29 PF13555.1 EXF80647.1 - 0.0061 16.0 0.1 0.025 14.0 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EXF80647.1 - 0.0092 15.1 0.0 0.05 12.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA PF00004.24 EXF80647.1 - 0.011 15.8 0.8 0.3 11.2 0.1 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EXF80647.1 - 0.055 12.3 0.0 0.11 11.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 EXF80647.1 - 0.071 12.4 0.0 0.21 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.10 EXF80647.1 - 0.11 11.2 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein PduV-EutP PF10662.4 EXF80647.1 - 0.12 11.8 0.0 0.33 10.4 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EXF80647.1 - 0.19 11.6 0.1 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EXF80647.1 - 0.24 10.8 0.2 1.8 8.0 0.3 2.3 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 EXF80647.1 - 0.24 11.6 0.1 0.53 10.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain Exo_endo_phos PF03372.18 EXF80649.1 - 7.8e-10 39.1 0.3 1.3e-09 38.4 0.2 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EXF80649.1 - 0.0083 15.7 0.0 0.033 13.8 0.0 2.0 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase HET PF06985.6 EXF80650.1 - 8e-25 87.6 0.1 2.2e-24 86.1 0.1 1.8 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SelR PF01641.13 EXF80651.1 - 1.1e-48 163.9 0.0 1.4e-48 163.6 0.0 1.1 1 0 0 1 1 1 1 SelR domain DZR PF12773.2 EXF80651.1 - 0.17 11.7 2.3 4.2 7.2 1.9 2.3 1 1 1 2 2 2 0 Double zinc ribbon Glyoxalase PF00903.20 EXF80652.1 - 4.4e-38 130.1 0.2 4.1e-18 65.5 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EXF80652.1 - 2.4e-31 108.5 0.0 2.6e-14 53.7 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EXF80652.1 - 9.9e-19 67.3 0.1 3.2e-08 33.5 0.0 3.4 2 2 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EXF80652.1 - 1.2e-07 31.8 0.0 0.011 15.6 0.0 3.5 1 1 1 2 2 2 2 Glyoxalase-like domain CppA_N PF14506.1 EXF80652.1 - 0.0013 18.3 0.0 0.3 10.7 0.0 2.4 2 0 0 2 2 2 2 CppA N-terminal Piwi PF02171.12 EXF80653.1 - 2.9e-71 239.9 0.0 4.1e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 Piwi domain DUF1785 PF08699.5 EXF80653.1 - 2.4e-09 36.4 0.0 8.1e-09 34.7 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1785) PAZ PF02170.17 EXF80653.1 - 3.6e-06 26.3 0.0 8.1e-06 25.1 0.0 1.6 1 0 0 1 1 1 1 PAZ domain dCMP_cyt_deam_1 PF00383.17 EXF80654.1 - 9.6e-14 50.8 0.0 1.2e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region APOBEC_N PF08210.6 EXF80654.1 - 0.0011 18.5 0.0 0.0014 18.2 0.0 1.1 1 0 0 1 1 1 1 APOBEC-like N-terminal domain DnaJ PF00226.26 EXF80655.1 - 2.6e-23 81.4 4.1 3.5e-23 81.1 1.8 2.1 2 0 0 2 2 2 1 DnaJ domain DUF1635 PF07795.6 EXF80655.1 - 0.15 11.4 1.7 0.11 11.8 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) Glyco_hydro_81 PF03639.8 EXF80656.1 - 6e-203 675.7 4.8 7.9e-203 675.3 3.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Stn1 PF10451.4 EXF80656.1 - 1.3e-11 43.8 0.4 0.0001 21.2 0.0 2.2 2 0 0 2 2 2 2 Telomere regulation protein Stn1 Na_Ca_ex PF01699.19 EXF80658.1 - 4.9e-49 165.5 32.3 7.3e-26 90.4 6.8 2.4 3 0 0 3 3 3 2 Sodium/calcium exchanger protein Utp14 PF04615.8 EXF80659.1 - 9e-170 566.3 74.9 9e-170 566.3 51.9 2.3 1 1 1 2 2 2 1 Utp14 protein COX15-CtaA PF02628.10 EXF80660.1 - 9e-95 317.0 9.4 1.1e-94 316.6 6.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein tRNA-synt_2 PF00152.15 EXF80661.1 - 1.9e-87 293.1 0.7 2.6e-87 292.7 0.5 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EXF80661.1 - 7.7e-06 25.2 0.4 0.027 13.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 EXF80661.1 - 0.0048 16.7 0.0 0.014 15.2 0.0 1.9 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain Peptidase_S58 PF03576.9 EXF80663.1 - 8.5e-110 366.9 0.4 9.7e-110 366.7 0.3 1.0 1 0 0 1 1 1 1 Peptidase family S58 Fe-ADH PF00465.14 EXF80664.1 - 3.1e-99 332.0 0.0 4e-99 331.7 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EXF80664.1 - 1.2e-12 47.7 0.0 5.3e-10 39.0 0.0 2.3 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase Peripla_BP_6 PF13458.1 EXF80664.1 - 0.00079 18.8 0.2 0.0014 18.0 0.1 1.3 1 0 0 1 1 1 1 Periplasmic binding protein Deltaretro_Tax PF05599.6 EXF80664.1 - 0.16 12.2 4.6 0.57 10.5 2.1 2.4 2 0 0 2 2 2 0 Deltaretrovirus Tax protein 2OG-FeII_Oxy_2 PF13532.1 EXF80665.1 - 2.4e-29 102.5 0.0 3.3e-29 102.0 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EXF80665.1 - 0.012 16.1 0.0 0.025 15.0 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Pkinase PF00069.20 EXF80666.1 - 1.4e-71 240.6 0.0 1.8e-71 240.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF80666.1 - 1.3e-30 106.3 0.0 1.6e-30 106.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF80666.1 - 0.0022 17.0 0.0 0.0035 16.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EXF80666.1 - 0.0037 17.0 0.0 0.0056 16.4 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EXF80666.1 - 0.024 13.4 0.0 0.036 12.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 DUF3537 PF12056.3 EXF80667.1 - 8.6 4.9 5.3 17 4.0 3.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) ADH_zinc_N PF00107.21 EXF80670.1 - 7.2e-13 48.2 0.1 1.3e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF80670.1 - 0.0029 17.3 0.0 0.0066 16.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain WD40 PF00400.27 EXF80672.1 - 1.8e-11 43.4 20.0 1.2e-05 24.9 0.5 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat RWD PF05773.17 EXF80672.1 - 0.0013 18.6 0.0 0.0033 17.2 0.0 1.6 1 0 0 1 1 1 1 RWD domain zf-rbx1 PF12678.2 EXF80672.1 - 0.0088 16.1 3.6 0.024 14.7 2.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EXF80672.1 - 0.0089 15.8 6.2 0.021 14.6 4.3 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EXF80672.1 - 4.5 7.3 7.8 11 6.1 5.4 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) UQ_con PF00179.21 EXF80673.1 - 1.2e-47 160.8 0.0 1.4e-47 160.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EXF80673.1 - 9.6e-05 22.1 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.8 EXF80673.1 - 0.0034 17.0 0.1 0.0065 16.1 0.0 1.5 1 1 0 1 1 1 1 UEV domain RWD PF05773.17 EXF80673.1 - 0.034 14.0 0.0 0.044 13.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain HET PF06985.6 EXF80674.1 - 1.1e-23 83.9 0.0 2.8e-22 79.3 0.0 2.4 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GPI2 PF06432.6 EXF80676.1 - 3.1e-119 397.5 0.7 3.9e-119 397.1 0.5 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Ifi-6-16 PF06140.8 EXF80677.1 - 0.046 13.5 1.1 4.4 7.1 0.3 2.2 2 0 0 2 2 2 0 Interferon-induced 6-16 family MDMPI_N PF11716.3 EXF80677.1 - 0.053 13.9 0.0 0.077 13.4 0.0 1.2 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain DUF2271 PF10029.4 EXF80678.1 - 0.08 12.4 0.3 0.65 9.4 0.0 2.0 2 0 0 2 2 2 0 Predicted periplasmic protein (DUF2271) Ank_2 PF12796.2 EXF80679.1 - 3e-23 81.9 0.0 1.9e-09 37.7 0.0 3.8 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EXF80679.1 - 2e-15 55.7 2.9 1.4e-05 24.6 0.0 6.7 5 1 0 5 5 5 2 Ankyrin repeat Ank_4 PF13637.1 EXF80679.1 - 5.4e-15 55.4 5.2 5.4e-06 26.7 0.2 5.9 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF80679.1 - 1.8e-12 46.1 2.1 0.01 16.0 0.0 6.6 7 0 0 7 7 7 3 Ankyrin repeat Ank_5 PF13857.1 EXF80679.1 - 1.6e-10 40.8 0.7 0.012 15.8 0.1 5.9 3 2 3 6 6 6 3 Ankyrin repeats (many copies) NACHT PF05729.7 EXF80679.1 - 2.7e-05 23.8 0.3 0.0002 21.0 0.2 2.4 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EXF80679.1 - 0.00023 21.1 1.7 0.00057 19.9 0.2 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EXF80679.1 - 0.0035 17.4 0.0 0.015 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain KAP_NTPase PF07693.9 EXF80679.1 - 0.075 12.0 0.6 0.9 8.4 0.1 2.2 1 1 0 2 2 2 0 KAP family P-loop domain Lyase_1 PF00206.15 EXF80680.1 - 3.7e-113 377.8 0.0 4.9e-113 377.4 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EXF80680.1 - 1.4e-22 79.4 0.0 3.1e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus AKNA PF12443.3 EXF80680.1 - 0.011 15.7 0.1 0.025 14.5 0.0 1.6 1 0 0 1 1 1 0 AT-hook-containing transcription factor Annexin PF00191.15 EXF80682.1 - 4.8e-17 61.6 0.2 0.00017 21.4 0.0 4.3 4 0 0 4 4 4 4 Annexin Myosin_head PF00063.16 EXF80683.1 - 5.7e-250 831.0 0.0 5.7e-250 831.0 0.0 2.6 2 0 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 EXF80683.1 - 2.5e-27 95.0 117.7 1.3e-26 92.6 58.3 7.0 3 2 4 7 7 7 5 Myosin tail Myosin_N PF02736.14 EXF80683.1 - 7.3e-06 25.5 0.4 7.3e-06 25.5 0.3 2.0 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain zf-CCCH PF00642.19 EXF80684.1 - 0.052 13.2 0.0 0.083 12.5 0.0 1.3 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Spc7 PF08317.6 EXF80684.1 - 0.063 11.9 9.4 0.14 10.8 6.5 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 EXF80684.1 - 1.7 6.4 5.1 2.5 5.8 3.5 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.6 EXF80684.1 - 6.3 5.3 6.2 10 4.6 4.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) RTA1 PF04479.8 EXF80685.1 - 7.2e-46 156.4 3.2 1.2e-45 155.7 2.2 1.3 1 0 0 1 1 1 1 RTA1 like protein Abhydro_lipase PF04083.11 EXF80686.1 - 5.1e-21 73.7 0.1 1e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EXF80686.1 - 2e-19 70.0 0.1 4e-19 69.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EXF80686.1 - 6.1e-06 26.2 0.0 1.5e-05 25.0 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EXF80686.1 - 0.00025 20.5 0.1 0.19 11.1 0.0 2.3 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EXF80686.1 - 0.001 18.8 0.0 0.0063 16.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EXF80686.1 - 0.085 12.2 0.1 7.7 5.8 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Pet191_N PF10203.4 EXF80687.1 - 5.4e-28 96.8 4.6 7e-28 96.4 3.2 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 PAN_3 PF08277.7 EXF80687.1 - 0.076 12.6 0.6 0.14 11.7 0.4 1.4 1 0 0 1 1 1 0 PAN-like domain Macin PF14865.1 EXF80687.1 - 3.9 7.6 5.6 16 5.6 1.0 2.2 2 0 0 2 2 2 0 Macin ACPS PF01648.15 EXF80688.1 - 1.8e-06 27.7 0.0 9.9e-06 25.3 0.0 2.2 2 1 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily HCO3_cotransp PF00955.16 EXF80690.1 - 2.2e-52 178.4 12.7 5.7e-29 101.1 0.1 2.2 1 1 1 2 2 2 2 HCO3- transporter family adh_short PF00106.20 EXF80690.1 - 1.4e-07 31.6 0.0 2.2e-06 27.7 0.0 2.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF80690.1 - 0.00025 20.8 0.0 0.22 11.2 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase MMR_HSR1 PF01926.18 EXF80691.1 - 1.1e-11 44.6 0.0 1.9e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EXF80691.1 - 4.9e-05 22.5 0.2 8.6e-05 21.7 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 FeoB_N PF02421.13 EXF80691.1 - 0.0021 17.3 0.0 0.0056 15.9 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B ArgK PF03308.11 EXF80691.1 - 0.0066 15.2 0.0 0.017 13.8 0.0 1.7 2 0 0 2 2 2 1 ArgK protein AAA_17 PF13207.1 EXF80691.1 - 0.03 15.1 0.1 0.35 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain Arf PF00025.16 EXF80691.1 - 0.032 13.4 0.0 0.052 12.7 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family AAA_18 PF13238.1 EXF80691.1 - 0.056 13.7 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EXF80691.1 - 0.069 13.1 0.4 0.26 11.2 0.1 1.9 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 EXF80691.1 - 0.11 12.1 0.1 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B PHD PF00628.24 EXF80692.1 - 7.7e-10 38.3 1.9 1.7e-09 37.2 1.3 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EXF80692.1 - 0.0019 17.4 3.4 0.0032 16.7 2.3 1.4 1 0 0 1 1 1 1 PHD-finger UIM PF02809.15 EXF80692.1 - 0.0032 16.8 1.2 0.01 15.2 0.8 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif PHD PF00628.24 EXF80695.1 - 3.7e-08 32.9 8.7 6.2e-08 32.2 6.0 1.4 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EXF80695.1 - 0.0025 18.0 0.0 0.0071 16.6 0.0 1.9 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding zf-HC5HC2H PF13771.1 EXF80695.1 - 0.22 11.7 1.6 0.46 10.6 1.1 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 EXF80695.1 - 6.7 6.8 7.2 11 6.1 5.0 1.3 1 0 0 1 1 1 0 RING-like domain AAA PF00004.24 EXF80696.1 - 1.1e-25 90.3 0.0 1.8e-13 50.8 0.0 2.7 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EXF80696.1 - 3.9e-10 39.9 1.3 0.00013 22.1 0.1 4.4 3 1 0 3 3 3 2 AAA domain RuvB_N PF05496.7 EXF80696.1 - 8.8e-09 34.7 0.0 0.00077 18.5 0.0 3.2 2 2 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EXF80696.1 - 1e-08 36.0 0.2 0.01 16.6 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.9 EXF80696.1 - 1.7e-08 34.2 0.2 0.0068 16.1 0.0 3.8 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EXF80696.1 - 1.2e-07 31.3 0.1 0.025 14.3 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain IstB_IS21 PF01695.12 EXF80696.1 - 1.3e-05 24.6 1.8 0.012 15.0 0.0 3.5 3 1 0 3 3 3 1 IstB-like ATP binding protein AAA_14 PF13173.1 EXF80696.1 - 5.5e-05 23.0 0.0 0.071 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EXF80696.1 - 8e-05 22.5 0.0 0.61 9.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EXF80696.1 - 0.00012 21.6 0.0 0.39 10.1 0.0 2.7 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.16 EXF80696.1 - 0.00013 21.1 0.1 0.58 9.2 0.0 2.9 2 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EXF80696.1 - 0.00014 22.2 2.9 0.23 11.7 0.2 3.2 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EXF80696.1 - 0.00018 21.5 1.5 1.6 8.7 0.0 3.9 4 1 0 4 4 4 2 AAA ATPase domain AAA_24 PF13479.1 EXF80696.1 - 0.00036 20.1 0.6 0.55 9.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 EXF80696.1 - 0.00042 19.8 0.1 0.16 11.4 0.0 3.9 2 2 1 3 3 3 1 Sigma-54 interaction domain AAA_28 PF13521.1 EXF80696.1 - 0.00073 19.5 0.1 1 9.2 0.1 2.7 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EXF80696.1 - 0.0016 18.6 0.1 1.8 8.7 0.0 3.0 3 0 0 3 3 2 1 RNA helicase AAA_10 PF12846.2 EXF80696.1 - 0.0048 16.3 2.7 2.6 7.4 0.0 3.7 3 1 1 4 4 3 1 AAA-like domain AAA_11 PF13086.1 EXF80696.1 - 0.031 13.8 3.3 2.1 7.8 0.1 3.1 3 1 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EXF80696.1 - 0.057 12.8 4.6 4.7 6.5 0.0 3.5 2 2 1 3 3 3 0 AAA domain AAA_30 PF13604.1 EXF80696.1 - 0.08 12.5 1.9 3 7.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain Torsin PF06309.6 EXF80696.1 - 0.099 12.5 0.0 0.79 9.6 0.0 2.3 2 0 0 2 2 2 0 Torsin Zot PF05707.7 EXF80696.1 - 0.15 11.4 0.7 39 3.6 0.2 3.6 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) Bactofilin PF04519.8 EXF80697.1 - 2.4e-05 24.2 1.7 0.00078 19.4 1.0 2.4 1 1 1 2 2 2 2 Polymer-forming cytoskeletal MinC_C PF03775.11 EXF80697.1 - 0.0014 18.1 3.2 0.11 12.1 0.4 2.5 1 1 1 2 2 2 2 Septum formation inhibitor MinC, C-terminal domain DUF342 PF03961.8 EXF80697.1 - 0.016 13.6 3.0 0.059 11.7 2.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF342) DUF1604 PF07713.8 EXF80699.1 - 0.012 15.3 1.4 0.038 13.7 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1604) zf-C2H2 PF00096.21 EXF80699.1 - 0.017 15.4 3.2 0.053 13.8 2.2 1.9 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-BED PF02892.10 EXF80699.1 - 0.04 13.6 1.9 0.085 12.6 1.3 1.5 1 0 0 1 1 1 0 BED zinc finger zf-C2H2_4 PF13894.1 EXF80699.1 - 0.3 11.5 2.4 0.98 9.9 1.7 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger DUF3602 PF12223.3 EXF80700.1 - 1.2e-10 41.6 13.3 0.00012 22.3 1.0 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Ribosomal_L24e PF01246.15 EXF80701.1 - 6.6e-30 102.7 3.2 1.4e-29 101.7 2.2 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e DUF1974 PF09317.6 EXF80701.1 - 0.052 12.9 1.0 0.07 12.5 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1974) Tox-REase-2 PF15646.1 EXF80701.1 - 0.66 9.8 6.0 1.4 8.8 1.3 2.5 2 1 0 2 2 2 0 Restriction endonuclease fold toxin 2 DnaJ PF00226.26 EXF80702.1 - 2.3e-07 30.4 0.0 2.9e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EXF80702.1 - 7.7e-07 28.9 0.0 8.8e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Pam16 TMP_2 PF06791.8 EXF80702.1 - 0.12 11.9 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Prophage tail length tape measure protein DUF3918 PF13056.1 EXF80702.1 - 0.28 10.5 1.5 0.79 9.0 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3918) PAP_RNA-bind PF04926.10 EXF80703.1 - 0.046 13.2 0.1 0.17 11.4 0.0 2.0 2 0 0 2 2 2 0 Poly(A) polymerase predicted RNA binding domain Ku PF02735.11 EXF80704.1 - 3.2e-25 88.7 0.0 6.1e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EXF80704.1 - 3.3e-22 79.0 0.1 8.1e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_PK_bind PF08785.6 EXF80704.1 - 2e-13 50.2 0.0 4.9e-13 49.0 0.0 1.7 1 0 0 1 1 1 1 Ku C terminal domain like VWA_2 PF13519.1 EXF80704.1 - 0.00043 20.4 0.2 0.0025 17.9 0.0 2.3 2 1 1 3 3 3 1 von Willebrand factor type A domain VWA PF00092.23 EXF80704.1 - 0.0082 15.8 0.1 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain MutS_III PF05192.13 EXF80704.1 - 0.1 12.3 0.4 0.72 9.5 0.1 2.1 2 0 0 2 2 2 0 MutS domain III DUF4149 PF13664.1 EXF80705.1 - 4.5e-23 81.2 4.9 4.5e-23 81.2 3.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4149) DUF1624 PF07786.7 EXF80705.1 - 0.18 11.1 1.9 0.35 10.1 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1624) Hydrolase_6 PF13344.1 EXF80707.1 - 3.6e-14 52.4 0.0 6.2e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EXF80707.1 - 1.4e-13 50.3 0.1 1.2e-12 47.3 0.0 2.4 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.21 EXF80707.1 - 7.6e-07 29.7 0.0 1.7e-06 28.5 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF1295 PF06966.7 EXF80708.1 - 5.1e-32 111.0 10.0 6.3e-32 110.7 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EXF80708.1 - 0.098 12.8 4.0 0.12 12.5 0.3 2.6 2 1 1 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Topoisom_bac PF01131.15 EXF80709.1 - 1.6e-95 320.3 0.0 1.4e-89 300.7 0.0 2.1 2 0 0 2 2 2 2 DNA topoisomerase Toprim PF01751.17 EXF80709.1 - 9.2e-19 67.2 0.0 2.3e-18 65.9 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.1 EXF80709.1 - 0.11 12.5 0.1 2 8.5 0.0 2.8 3 0 0 3 3 3 0 Toprim domain Stb3 PF10330.4 EXF80710.1 - 9.5e-37 124.5 0.0 1.6e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Putative Sin3 binding protein PD40 PF07676.7 EXF80711.1 - 1.5e-46 155.3 19.0 4.7e-07 29.3 0.0 9.9 9 0 0 9 9 9 9 WD40-like Beta Propeller Repeat ADH_zinc_N PF00107.21 EXF80711.1 - 2.1e-14 53.1 0.1 6e-14 51.7 0.1 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DPPIV_N PF00930.16 EXF80711.1 - 1.2e-11 43.8 6.8 0.019 13.5 0.1 7.1 4 2 2 7 7 7 5 Dipeptidyl peptidase IV (DPP IV) N-terminal region ADH_N PF08240.7 EXF80711.1 - 1.7e-05 24.5 0.4 8.9e-05 22.2 0.2 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EXF80711.1 - 0.025 15.4 0.0 0.092 13.6 0.0 2.0 1 0 0 1 1 1 0 Zinc-binding dehydrogenase WD40 PF00400.27 EXF80711.1 - 4.7 7.2 6.2 1.5e+02 2.5 0.1 5.3 6 0 0 6 6 6 0 WD domain, G-beta repeat adh_short PF00106.20 EXF80712.1 - 5.1e-20 72.0 2.7 7e-20 71.6 1.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF80712.1 - 3.7e-11 43.2 0.2 4.5e-11 42.9 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EXF80712.1 - 0.026 13.6 0.0 0.071 12.2 0.0 1.6 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EXF80712.1 - 0.029 14.3 0.3 0.049 13.6 0.2 1.4 1 0 0 1 1 1 0 NADH(P)-binding NmrA PF05368.8 EXF80712.1 - 0.029 13.6 0.2 0.056 12.6 0.1 1.4 1 0 0 1 1 1 0 NmrA-like family 2-Hacid_dh_C PF02826.14 EXF80712.1 - 0.059 12.5 0.0 0.85 8.7 0.0 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ubiquitin PF00240.18 EXF80712.1 - 0.079 12.3 0.9 0.095 12.1 0.1 1.6 2 0 0 2 2 2 0 Ubiquitin family ADH_N PF08240.7 EXF80713.1 - 4.9e-25 87.4 5.6 8e-25 86.7 3.9 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF80713.1 - 4.3e-16 58.6 0.2 6.2e-16 58.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF80713.1 - 0.0036 18.2 0.0 0.0064 17.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 EXF80713.1 - 0.039 13.5 0.2 0.058 12.9 0.2 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase zf-C2H2 PF00096.21 EXF80715.1 - 4.9e-07 29.7 17.3 9.4e-06 25.6 2.6 3.7 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EXF80715.1 - 6.7e-05 22.9 9.7 7.3e-05 22.8 3.0 3.0 2 0 0 2 2 2 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EXF80715.1 - 0.00029 20.8 1.7 0.00096 19.2 0.7 2.3 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EXF80715.1 - 0.00042 20.4 1.1 0.00042 20.4 0.8 3.7 3 0 0 3 3 3 1 C2H2-type zinc finger zf-met PF12874.2 EXF80715.1 - 0.0092 16.1 1.9 0.14 12.4 0.6 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type DUF629 PF04780.7 EXF80715.1 - 0.047 12.2 2.8 1.2 7.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF629) zf-TRAF PF02176.13 EXF80715.1 - 0.41 11.0 7.1 0.087 13.2 2.2 1.9 2 0 0 2 2 2 0 TRAF-type zinc finger zf-C2H2_2 PF12756.2 EXF80715.1 - 8.6 6.5 8.2 3.9 7.6 2.7 2.6 2 1 1 3 3 3 0 C2H2 type zinc-finger (2 copies) Pyr_redox_3 PF13738.1 EXF80717.1 - 1.1e-18 68.0 0.0 2.2e-18 67.0 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EXF80717.1 - 6.2e-16 57.6 0.8 8.7e-14 50.6 0.4 2.7 2 2 0 2 2 2 2 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EXF80717.1 - 1.1e-08 34.4 0.0 1.2e-05 24.4 0.0 3.4 4 0 0 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EXF80717.1 - 5.1e-06 26.4 0.0 1.2e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EXF80717.1 - 0.024 14.3 0.1 1.2 8.8 0.0 2.7 3 0 0 3 3 3 0 FAD-NAD(P)-binding MFS_1 PF07690.11 EXF80718.1 - 7.1e-32 110.4 25.1 1.6e-31 109.3 17.7 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily NAD_binding_2 PF03446.10 EXF80719.1 - 3.7e-19 69.1 0.0 8e-19 68.0 0.0 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EXF80719.1 - 1.4e-10 41.3 0.0 2.4e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DUF2580 PF10824.3 EXF80719.1 - 0.057 13.7 0.5 0.057 13.7 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2580) Homez PF11569.3 EXF80719.1 - 0.075 12.1 0.0 0.17 10.9 0.0 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez Fungal_trans PF04082.13 EXF80720.1 - 4.9e-10 38.7 2.4 8.3e-10 37.9 1.7 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EXF80720.1 - 2.8e-05 24.1 14.6 4.9e-05 23.4 1.7 2.7 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EXF80720.1 - 0.00067 19.8 8.2 0.014 15.6 1.0 2.5 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EXF80720.1 - 0.0013 18.8 15.5 0.023 14.9 1.9 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EXF80720.1 - 0.0029 17.4 6.5 0.012 15.4 0.5 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger Mon1 PF03164.9 EXF80720.1 - 0.044 12.3 0.1 0.079 11.5 0.1 1.4 1 0 0 1 1 1 0 Trafficking protein Mon1 PGM_PMM_IV PF00408.15 EXF80720.1 - 0.13 12.3 0.9 7.6 6.6 0.0 2.4 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain zf-met2 PF12907.2 EXF80720.1 - 0.16 11.9 3.0 0.58 10.1 0.1 2.5 2 0 0 2 2 2 0 Zinc-binding zf-H2C2_5 PF13909.1 EXF80720.1 - 2 8.7 7.7 0.077 13.2 1.0 2.0 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-met PF12874.2 EXF80720.1 - 8.7 6.7 6.5 8.6 6.7 0.4 2.5 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Thioredoxin_6 PF13848.1 EXF80722.1 - 1.1e-19 71.0 0.0 2.5e-14 53.4 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin PF00085.15 EXF80722.1 - 1.4e-08 34.3 0.0 5.5e-07 29.2 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin DUF4620 PF15399.1 EXF80723.1 - 0.2 11.7 2.6 0.22 11.6 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) SET PF00856.23 EXF80724.1 - 2.1e-06 28.1 0.1 0.051 13.8 0.0 2.9 3 1 0 3 3 3 2 SET domain TPR_11 PF13414.1 EXF80724.1 - 0.0028 17.2 0.1 2.4 7.8 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.1 EXF80724.1 - 0.046 14.4 0.4 0.22 12.2 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-MYND PF01753.13 EXF80724.1 - 3.4 7.6 13.2 0.27 11.1 4.8 2.5 2 0 0 2 2 2 0 MYND finger Fungal_trans_2 PF11951.3 EXF80725.1 - 0.0012 17.5 0.6 0.0015 17.1 0.4 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 EXF80726.1 - 1.5e-50 171.8 9.3 2e-50 171.4 6.4 1.1 1 0 0 1 1 1 1 RTA1 like protein MFS_1 PF07690.11 EXF80728.1 - 1.8e-26 92.6 67.2 3.5e-20 72.0 27.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1228 PF06779.9 EXF80728.1 - 5e-06 26.4 0.2 5e-06 26.4 0.1 3.6 3 1 0 3 3 3 1 Protein of unknown function (DUF1228) MFS_3 PF05977.8 EXF80728.1 - 0.034 12.2 18.0 0.049 11.7 3.1 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector DUF3425 PF11905.3 EXF80730.1 - 0.00016 21.5 0.5 0.00057 19.7 0.3 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF3425) DUF3248 PF11609.3 EXF80730.1 - 0.013 15.1 0.1 0.11 12.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3248) DUF4643 PF15485.1 EXF80730.1 - 0.023 14.2 1.7 0.035 13.5 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4643) HlyD PF00529.15 EXF80730.1 - 0.15 11.3 7.3 0.23 10.7 5.1 1.2 1 0 0 1 1 1 0 HlyD family secretion protein bZIP_1 PF00170.16 EXF80730.1 - 0.19 11.6 19.9 6.3 6.8 0.1 3.2 2 1 1 3 3 3 0 bZIP transcription factor ABC_tran_2 PF12848.2 EXF80730.1 - 1.7 8.5 8.2 3.4 7.5 5.7 1.4 1 0 0 1 1 1 0 ABC transporter p450 PF00067.17 EXF80732.1 - 3.7e-39 134.5 0.0 1.3e-38 132.7 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 Bac_rhamnosid PF05592.6 EXF80733.1 - 1.9e-175 583.9 0.0 2.3e-175 583.6 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 EXF80733.1 - 8.2e-48 162.1 0.0 2.6e-47 160.5 0.0 1.7 2 0 0 2 2 2 1 Alpha-L-rhamnosidase N-terminal domain Sugar_tr PF00083.19 EXF80734.1 - 4.5e-86 289.2 30.1 5.1e-86 289.0 20.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF80734.1 - 1e-29 103.3 40.3 1.8e-28 99.2 21.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF80734.1 - 3.5e-06 25.5 4.5 3.5e-06 25.5 3.1 2.1 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Epimerase PF01370.16 EXF80735.1 - 9.2e-20 71.0 0.0 1.2e-19 70.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EXF80735.1 - 6.2e-09 34.9 0.0 8e-09 34.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EXF80735.1 - 4.4e-07 29.0 0.0 3.6e-05 22.8 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EXF80735.1 - 4.6e-06 26.7 0.0 7.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EXF80735.1 - 9.1e-06 24.7 0.0 1.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EXF80735.1 - 0.00033 20.6 0.0 0.00068 19.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EXF80737.1 - 2.9e-32 111.7 0.0 3.4e-32 111.5 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EXF80737.1 - 0.0019 16.9 0.0 0.0025 16.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EXF80737.1 - 0.0024 17.8 0.1 0.0048 16.9 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding PAP2_3 PF14378.1 EXF80738.1 - 9.8e-18 64.3 7.3 2.8e-13 49.8 2.4 2.3 2 0 0 2 2 2 2 PAP2 superfamily RtcB PF01139.12 EXF80738.1 - 0.0047 15.9 0.0 0.0065 15.5 0.0 1.1 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Fungal_trans PF04082.13 EXF80739.1 - 3.3e-11 42.5 0.1 7.5e-11 41.3 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.16 EXF80740.1 - 4.4e-92 308.2 0.0 7.9e-92 307.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF80740.1 - 1e-56 192.0 1.6 5.5e-56 189.6 0.4 2.2 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF80740.1 - 3.7e-18 65.2 0.0 8.3e-18 64.1 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III-like domain COX1 PF00115.15 EXF80740.1 - 0.15 10.6 0.0 0.21 10.1 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I ERG4_ERG24 PF01222.12 EXF80741.1 - 1.6e-166 554.1 0.6 1.9e-166 553.9 0.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EXF80741.1 - 0.00013 21.3 0.2 0.00036 19.9 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Man-6-P_recep PF02157.10 EXF80742.1 - 5.6e-10 38.6 0.0 8.8e-10 38.0 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 EXF80742.1 - 2.1e-09 37.3 0.2 0.00028 20.6 0.0 2.3 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat ATG27 PF09451.5 EXF80742.1 - 2e-05 23.9 1.6 0.0002 20.7 1.0 2.4 1 1 0 1 1 1 1 Autophagy-related protein 27 YqzM PF14141.1 EXF80742.1 - 1.2 8.9 4.7 1.4 8.8 0.7 2.3 2 0 0 2 2 2 0 YqzM-like protein PBP1_TM PF14812.1 EXF80742.1 - 3 8.2 5.2 4.3 7.7 0.3 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Aldo_ket_red PF00248.16 EXF80743.1 - 3.8e-49 167.0 0.0 4.4e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HET PF06985.6 EXF80744.1 - 9.7e-26 90.5 0.5 1.8e-25 89.6 0.4 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) bZIP_1 PF00170.16 EXF80745.1 - 1.7e-08 34.2 9.7 2.8e-08 33.5 6.7 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EXF80745.1 - 2.9e-06 26.9 11.7 4.9e-06 26.2 8.1 1.4 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EXF80745.1 - 0.013 15.7 6.0 0.013 15.7 4.1 1.6 2 0 0 2 2 2 0 bZIP Maf transcription factor SlyX PF04102.7 EXF80745.1 - 0.11 12.9 1.0 0.23 11.8 0.7 1.6 1 0 0 1 1 1 0 SlyX CAF-1_p150 PF11600.3 EXF80745.1 - 0.13 11.5 5.3 0.18 11.1 3.7 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal MCC-bdg_PDZ PF10506.4 EXF80745.1 - 0.21 11.4 2.7 2 8.2 0.2 2.3 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome GrpE PF01025.14 EXF80745.1 - 0.32 10.5 3.9 0.46 10.0 2.7 1.3 1 0 0 1 1 1 0 GrpE NmrA PF05368.8 EXF80746.1 - 2.3e-21 76.1 0.2 3.3e-21 75.6 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF80746.1 - 6.2e-18 65.4 0.1 1.2e-17 64.5 0.0 1.5 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EXF80746.1 - 2.9e-06 26.9 0.3 4.4e-06 26.3 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EXF80746.1 - 5.5e-05 22.3 2.3 0.0032 16.5 0.3 2.1 2 0 0 2 2 2 2 Saccharopine dehydrogenase F420_oxidored PF03807.12 EXF80746.1 - 6.5e-05 23.2 1.9 8.3e-05 22.9 0.3 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent CoA_binding_2 PF13380.1 EXF80746.1 - 0.00021 21.4 0.9 0.042 14.0 0.2 2.3 2 0 0 2 2 2 1 CoA binding domain adh_short PF00106.20 EXF80746.1 - 0.0012 18.7 0.4 0.0027 17.6 0.3 1.6 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EXF80746.1 - 0.0021 16.8 0.2 0.0034 16.1 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_2 PF03446.10 EXF80746.1 - 0.0055 16.5 0.9 0.0084 15.9 0.2 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Semialdhyde_dh PF01118.19 EXF80746.1 - 0.0065 16.7 1.9 0.019 15.2 0.4 2.0 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain RmlD_sub_bind PF04321.12 EXF80746.1 - 0.01 14.7 0.1 0.016 14.0 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_7 PF13241.1 EXF80746.1 - 0.032 14.4 0.7 0.08 13.1 0.5 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding XdhC_C PF13478.1 EXF80746.1 - 0.039 14.2 0.1 0.072 13.4 0.0 1.4 1 0 0 1 1 1 0 XdhC Rossmann domain DapB_N PF01113.15 EXF80746.1 - 0.06 13.2 1.8 0.097 12.5 0.3 2.1 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus GST_C_2 PF13410.1 EXF80746.1 - 0.096 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DC_STAMP PF07782.8 EXF80746.1 - 0.14 11.8 0.0 0.27 10.8 0.0 1.4 1 0 0 1 1 1 0 DC-STAMP-like protein 3HCDH_N PF02737.13 EXF80746.1 - 0.17 11.5 2.6 0.11 12.1 0.5 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Acetyltransf_7 PF13508.1 EXF80747.1 - 1.7e-05 24.8 0.0 4.4e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EXF80747.1 - 0.00077 19.4 0.1 0.0018 18.2 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EXF80747.1 - 0.0083 16.2 0.1 0.03 14.4 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 EXF80747.1 - 0.011 15.0 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 MOZ/SAS family Acetyltransf_9 PF13527.1 EXF80747.1 - 0.053 13.3 0.0 0.73 9.6 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Dioxygenase_C PF00775.16 EXF80748.1 - 2.2e-06 27.0 0.0 5.2e-06 25.8 0.0 1.8 1 1 0 1 1 1 1 Dioxygenase MAPEG PF01124.13 EXF80750.1 - 5.8e-20 71.2 0.1 6.8e-20 70.9 0.0 1.0 1 0 0 1 1 1 1 MAPEG family RAP1 PF07218.6 EXF80752.1 - 9 4.2 6.8 9.6 4.1 4.7 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) MFS_1 PF07690.11 EXF80754.1 - 9.8e-38 129.7 28.3 9.8e-38 129.7 19.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EXF80754.1 - 0.00017 19.9 0.4 0.00029 19.1 0.2 1.3 1 0 0 1 1 1 1 Transmembrane secretion effector TRI12 PF06609.8 EXF80754.1 - 0.0012 17.0 5.4 0.0012 17.0 3.8 1.6 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) FGase PF05013.7 EXF80756.1 - 0.037 13.9 0.0 0.053 13.4 0.0 1.3 1 0 0 1 1 1 0 N-formylglutamate amidohydrolase DUF221 PF02714.10 EXF80757.1 - 5.9e-105 350.7 10.2 5.9e-105 350.7 7.0 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EXF80757.1 - 5.3e-39 133.2 6.3 2.1e-38 131.3 4.4 2.1 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport DUF3779 PF12621.3 EXF80757.1 - 3.8e-29 100.4 0.1 1.5e-26 92.1 0.0 2.4 2 0 0 2 2 2 2 Phosphate metabolism protein DUF4463 PF14703.1 EXF80757.1 - 2.2e-12 47.3 0.1 5.1e-12 46.1 0.0 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4463) RRM_6 PF14259.1 EXF80757.1 - 0.0021 17.9 0.0 0.0062 16.4 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EXF80757.1 - 0.0091 15.6 0.0 0.02 14.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF80757.1 - 0.011 15.5 0.0 0.044 13.6 0.0 2.0 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Transferase PF02458.10 EXF80758.1 - 3.3e-08 32.3 0.0 1.8e-07 29.9 0.0 2.1 2 1 0 2 2 2 1 Transferase family TauD PF02668.11 EXF80759.1 - 2.4e-47 161.7 0.2 2.8e-47 161.5 0.1 1.0 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family 2OG-FeII_Oxy_3 PF13640.1 EXF80759.1 - 0.0064 16.9 0.8 0.61 10.6 0.0 2.6 1 1 1 2 2 2 2 2OG-Fe(II) oxygenase superfamily F-box-like PF12937.2 EXF80760.1 - 3.4e-05 23.4 0.2 0.019 14.6 0.0 3.4 3 0 0 3 3 3 2 F-box-like Fungal_trans PF04082.13 EXF80761.1 - 7.9e-37 126.5 0.0 1.3e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_5 PF00266.14 EXF80761.1 - 2e-33 115.6 0.0 1.3e-32 112.9 0.0 2.1 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EXF80761.1 - 0.029 13.3 0.0 0.057 12.3 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Zn_clus PF00172.13 EXF80761.1 - 0.06 13.2 14.5 0.17 11.8 10.1 1.7 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain CVNH PF08881.5 EXF80763.1 - 1.2e-29 102.6 1.3 1.6e-29 102.1 0.9 1.2 1 0 0 1 1 1 1 CVNH domain Ribosomal_L50 PF10501.4 EXF80765.1 - 3.5e-22 78.5 0.0 8e-22 77.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal subunit 39S SAP PF02037.22 EXF80765.1 - 0.048 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 SAP domain PV-1 PF06637.6 EXF80766.1 - 0.082 11.4 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) DAHP_synth_1 PF00793.15 EXF80767.1 - 2.4e-98 328.1 0.1 2.9e-98 327.9 0.1 1.0 1 0 0 1 1 1 1 DAHP synthetase I family COX14 PF14880.1 EXF80769.1 - 1.9e-20 72.2 1.7 2.1e-20 72.1 0.2 1.9 2 0 0 2 2 2 1 Cytochrome oxidase c assembly CytochromB561_N PF09786.4 EXF80769.1 - 0.4 9.0 9.7 0.0075 14.7 0.6 1.9 1 1 0 2 2 2 0 Cytochrome B561, N terminal SOBP PF15279.1 EXF80769.1 - 2.2 8.5 10.9 1.5 9.1 6.2 1.6 1 1 1 2 2 2 0 Sine oculis-binding protein Ribosomal_L13e PF01294.13 EXF80770.1 - 2.6e-67 225.7 2.7 3.3e-67 225.4 1.8 1.2 1 0 0 1 1 1 1 Ribosomal protein L13e mIF3 PF14877.1 EXF80771.1 - 0.2 10.9 0.0 0.35 10.2 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial translation initiation factor Arm PF00514.18 EXF80771.1 - 0.29 11.0 4.3 16 5.5 0.1 5.1 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Sugar_tr PF00083.19 EXF80773.1 - 8.1e-78 261.9 24.0 9.8e-78 261.7 16.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF80773.1 - 5e-31 107.6 55.6 4.4e-25 88.1 21.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF80773.1 - 0.00011 20.6 1.7 0.00011 20.6 1.2 2.3 2 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Aldo_ket_red PF00248.16 EXF80774.1 - 8.4e-66 221.6 0.1 9.5e-66 221.4 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FMO-like PF00743.14 EXF80775.1 - 5.2e-57 193.2 0.0 1.1e-56 192.1 0.0 1.5 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EXF80775.1 - 5.3e-21 75.6 0.0 1.3e-20 74.3 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF80775.1 - 2.9e-10 40.3 0.0 3.6e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF80775.1 - 8.5e-09 35.3 0.2 0.007 16.1 0.0 4.1 3 1 1 4 4 4 2 FAD-NAD(P)-binding K_oxygenase PF13434.1 EXF80775.1 - 5.2e-08 32.1 0.8 1.5e-06 27.3 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EXF80775.1 - 7.3e-08 32.3 0.0 2.3e-07 30.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF80775.1 - 4.3e-07 29.1 0.1 0.012 14.5 0.0 2.6 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EXF80775.1 - 0.00063 20.1 0.0 0.022 15.1 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EXF80775.1 - 0.0029 16.6 0.2 0.054 12.5 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EXF80775.1 - 0.006 15.7 0.0 0.0092 15.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family NAD_binding_10 PF13460.1 EXF80775.1 - 0.01 15.8 0.1 0.029 14.3 0.0 1.8 2 0 0 2 2 2 0 NADH(P)-binding IlvN PF07991.7 EXF80775.1 - 0.088 12.1 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain NAD_binding_2 PF03446.10 EXF80775.1 - 0.09 12.6 0.0 0.3 10.9 0.0 1.8 2 0 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1593 PF07632.6 EXF80776.1 - 1.4e-99 332.6 0.0 1.8e-99 332.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.10 EXF80776.1 - 0.083 11.1 0.0 0.12 10.6 0.0 1.2 1 0 0 1 1 1 0 REJ domain Sugar_tr PF00083.19 EXF80777.1 - 1.5e-69 234.7 20.4 1.7e-69 234.5 14.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF80777.1 - 5.4e-18 64.8 23.7 5.4e-18 64.8 16.4 2.2 1 1 2 3 3 3 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EXF80777.1 - 0.00015 21.5 6.6 0.00037 20.2 0.1 3.5 4 0 0 4 4 4 1 MFS_1 like family MFS_1 PF07690.11 EXF80778.1 - 8.3e-39 133.2 39.2 8.3e-39 133.2 27.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF80778.1 - 1.3e-14 53.6 13.6 1.3e-14 53.6 9.4 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter Fungal_trans PF04082.13 EXF80779.1 - 1e-14 54.0 0.2 1.7e-14 53.3 0.1 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF80779.1 - 2.6e-07 30.4 9.9 4.8e-07 29.5 6.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BCMA-Tall_bind PF09257.5 EXF80779.1 - 0.97 9.4 6.7 3.3 7.7 4.7 2.0 1 0 0 1 1 1 0 BCMA, TALL-1 binding p450 PF00067.17 EXF80781.1 - 5.5e-52 176.8 0.0 7.8e-52 176.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Exo_endo_phos PF03372.18 EXF80783.1 - 7.5e-09 35.8 2.3 9.3e-09 35.5 1.6 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Methyltransf_23 PF13489.1 EXF80784.1 - 8.2e-19 67.8 0.0 1.8e-18 66.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF80784.1 - 9.2e-09 35.6 0.0 1.8e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF80784.1 - 8.9e-08 31.8 0.0 2e-06 27.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF80784.1 - 3.6e-07 30.7 0.0 6.6e-06 26.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF80784.1 - 5.3e-06 26.8 0.0 8.2e-05 23.0 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF80784.1 - 0.0057 15.7 0.0 0.019 14.0 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 EXF80784.1 - 0.018 14.1 0.0 0.23 10.5 0.0 2.4 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family MTS PF05175.9 EXF80784.1 - 0.03 13.7 0.0 0.18 11.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain PrmA PF06325.8 EXF80784.1 - 0.042 12.9 0.0 0.072 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 EXF80784.1 - 0.078 13.3 0.0 0.27 11.6 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_2 PF00891.13 EXF80785.1 - 2.1e-15 56.6 0.0 3.9e-15 55.7 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase NAD_binding_4 PF07993.7 EXF80788.1 - 3.1e-37 127.8 0.0 4.8e-37 127.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EXF80788.1 - 2.4e-36 125.0 0.0 4.3e-36 124.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EXF80788.1 - 1.3e-14 54.2 0.0 2.6e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EXF80788.1 - 5.1e-07 29.8 0.0 1.2e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site 3Beta_HSD PF01073.14 EXF80788.1 - 0.00015 20.5 0.0 0.015 14.0 0.0 2.1 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EXF80788.1 - 0.0022 17.9 0.7 0.0062 16.4 0.5 1.8 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF80788.1 - 0.0026 17.4 0.6 0.0074 15.9 0.4 1.7 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EXF80788.1 - 0.19 10.6 0.1 0.6 8.9 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Dak1 PF02733.12 EXF80789.1 - 6.6e-122 406.1 3.3 9.5e-122 405.6 2.3 1.2 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EXF80789.1 - 5.2e-45 153.2 5.5 1.3e-44 151.9 3.8 1.7 1 0 0 1 1 1 1 DAK2 domain ACT_7 PF13840.1 EXF80789.1 - 0.073 12.5 0.1 0.23 11.0 0.0 1.9 1 0 0 1 1 1 0 ACT domain Fungal_trans PF04082.13 EXF80790.1 - 2.4e-28 98.7 0.4 3.7e-28 98.1 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF80790.1 - 7.4e-08 32.1 9.8 7.4e-08 32.1 6.8 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclase PF04199.8 EXF80791.1 - 6e-16 58.6 0.0 8.9e-16 58.0 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase MFS_1 PF07690.11 EXF80792.1 - 1.4e-27 96.3 20.5 1.4e-27 96.3 13.6 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DHDPS PF00701.17 EXF80793.1 - 5.7e-29 100.6 0.0 6.5e-29 100.4 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Amidohydro_3 PF07969.6 EXF80793.1 - 0.003 16.8 0.0 0.0059 15.8 0.0 1.4 2 0 0 2 2 2 1 Amidohydrolase family DUF818 PF05677.7 EXF80793.1 - 0.062 12.0 0.0 0.092 11.4 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) Aldo_ket_red PF00248.16 EXF80794.1 - 7.2e-62 208.7 0.0 9e-62 208.4 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family MR_MLE_C PF13378.1 EXF80795.1 - 2.4e-34 117.6 0.0 4.7e-34 116.6 0.0 1.5 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE_N PF02746.11 EXF80795.1 - 1.6e-16 60.3 0.0 3.4e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MR_MLE PF01188.16 EXF80795.1 - 1.4e-09 38.3 0.0 3.9e-09 36.8 0.0 1.8 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain Amidohydro_2 PF04909.9 EXF80795.1 - 0.0022 17.6 0.2 0.005 16.4 0.1 1.8 1 1 0 1 1 1 1 Amidohydrolase Citrate_synt PF00285.16 EXF80797.1 - 7.1e-116 386.8 0.0 9.5e-116 386.4 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase NmrA PF05368.8 EXF80798.1 - 3.4e-22 78.8 0.4 7.4e-22 77.7 0.3 1.5 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF80798.1 - 4.4e-18 65.9 0.2 8e-18 65.0 0.1 1.6 2 1 0 2 2 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EXF80798.1 - 2.9e-08 33.0 0.7 2.2e-07 30.2 0.0 2.2 2 1 1 3 3 3 1 Saccharopine dehydrogenase Epimerase PF01370.16 EXF80798.1 - 1.6e-07 31.0 0.1 3.6e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EXF80798.1 - 7.2e-06 26.3 1.1 2.3e-05 24.7 0.0 2.3 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EXF80798.1 - 9.6e-06 25.5 0.3 0.0006 19.7 0.0 2.4 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus RmlD_sub_bind PF04321.12 EXF80798.1 - 6.5e-05 21.9 0.1 0.00058 18.8 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain 3HCDH_N PF02737.13 EXF80798.1 - 0.00017 21.3 0.0 0.00041 20.0 0.0 1.7 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EXF80798.1 - 0.00021 21.1 0.4 0.0074 16.1 0.0 2.3 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase DFP PF04127.10 EXF80798.1 - 0.00022 20.8 1.3 0.0013 18.3 0.1 2.1 2 0 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein 3Beta_HSD PF01073.14 EXF80798.1 - 0.00044 19.0 0.6 0.001 17.8 0.0 1.9 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EXF80798.1 - 0.0014 18.5 0.1 0.0032 17.4 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain IlvN PF07991.7 EXF80798.1 - 0.0018 17.6 0.2 0.0049 16.2 0.1 1.7 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EXF80798.1 - 0.004 17.5 1.4 0.012 16.0 0.1 2.3 2 1 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent DUF1341 PF07071.6 EXF80798.1 - 0.048 13.1 0.1 0.072 12.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1341) Ldh_1_N PF00056.18 EXF80798.1 - 0.06 13.1 0.3 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EXF80798.1 - 0.062 12.4 0.0 0.12 11.4 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.20 EXF80798.1 - 0.1 12.4 0.1 0.32 10.8 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase E1-E2_ATPase PF00122.15 EXF80799.1 - 7e-54 182.2 4.9 1.3e-53 181.4 3.4 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EXF80799.1 - 1.9e-40 138.3 4.8 1.9e-40 138.3 3.4 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EXF80799.1 - 4.3e-27 95.9 0.1 1.5e-25 90.8 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EXF80799.1 - 1.4e-19 69.8 0.0 3e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EXF80799.1 - 6e-12 46.1 0.0 3.7e-11 43.5 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EXF80799.1 - 2.3e-09 36.5 0.1 1.7e-08 33.8 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EXF80799.1 - 1.1e-05 25.1 0.1 0.0002 21.0 0.3 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Glycophorin_A PF01102.13 EXF80799.1 - 0.1 12.3 0.9 0.72 9.6 0.1 2.4 1 1 1 2 2 2 0 Glycophorin A Glyco_hydro_61 PF03443.9 EXF80800.1 - 1e-54 185.6 0.1 1.7e-54 184.9 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Fungal_trans PF04082.13 EXF80800.1 - 4.3e-16 58.5 0.1 6.9e-16 57.9 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain CBM_1 PF00734.13 EXF80800.1 - 6.6e-05 22.4 10.7 6.6e-05 22.4 7.4 2.5 2 0 0 2 2 2 1 Fungal cellulose binding domain Zn_clus PF00172.13 EXF80800.1 - 0.0023 17.8 8.9 0.0023 17.8 6.1 2.1 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Abhydrolase_3 PF07859.8 EXF80801.1 - 9.1e-55 185.4 0.0 1.2e-54 185.0 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EXF80801.1 - 2e-05 23.8 0.0 0.035 13.3 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.23 EXF80801.1 - 0.00024 19.9 0.3 0.00093 18.0 0.1 1.9 2 1 0 2 2 2 1 Carboxylesterase family Esterase_phd PF10503.4 EXF80801.1 - 0.0047 16.2 0.1 0.0088 15.3 0.1 1.4 1 0 0 1 1 1 1 Esterase PHB depolymerase Abhydrolase_5 PF12695.2 EXF80801.1 - 0.011 15.4 0.0 0.019 14.7 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.13 EXF80801.1 - 0.15 11.3 0.1 1.2 8.3 0.1 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family PTR2 PF00854.16 EXF80802.1 - 1.4e-32 112.8 6.3 3.1e-29 101.8 1.1 2.2 2 0 0 2 2 2 2 POT family RseC_MucC PF04246.7 EXF80802.1 - 0.0099 15.4 6.4 0.39 10.2 0.0 3.0 3 0 0 3 3 3 2 Positive regulator of sigma(E), RseC/MucC DUF1469 PF07332.6 EXF80802.1 - 0.11 12.2 0.1 0.11 12.2 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1469) p450 PF00067.17 EXF80804.1 - 1.3e-59 201.9 0.0 2.8e-59 200.8 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 TauD PF02668.11 EXF80806.1 - 9.9e-14 51.6 0.0 4.7e-12 46.1 0.0 2.1 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AA_kinase PF00696.23 EXF80809.1 - 8.6e-36 123.6 0.0 1.9e-35 122.5 0.0 1.6 1 0 0 1 1 1 1 Amino acid kinase family ACT_7 PF13840.1 EXF80809.1 - 5.4e-14 51.4 4.2 1.3e-11 43.8 2.4 2.5 2 0 0 2 2 2 2 ACT domain ACT PF01842.20 EXF80809.1 - 6.8e-07 28.6 1.2 2.2e-06 27.0 0.5 2.1 2 0 0 2 2 2 1 ACT domain Abhydrolase_1 PF00561.15 EXF80810.1 - 2.8e-31 108.8 0.0 3.1e-30 105.4 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EXF80810.1 - 7.2e-11 42.3 0.4 1.9e-10 41.0 0.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF80810.1 - 0.047 13.4 0.0 0.21 11.3 0.0 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_4 PF08386.5 EXF80810.1 - 0.051 13.4 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein CN_hydrolase PF00795.17 EXF80811.1 - 2e-33 115.3 0.0 2.9e-33 114.8 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Cys_Met_Meta_PP PF01053.15 EXF80812.1 - 5.4e-141 469.3 0.0 7.9e-141 468.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EXF80812.1 - 3.6e-09 36.1 0.1 1.8e-08 33.8 0.1 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_1_2 PF00155.16 EXF80812.1 - 5e-08 32.2 0.1 9e-08 31.4 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EXF80812.1 - 3.2e-07 29.4 0.1 6.2e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EXF80812.1 - 0.00011 21.4 0.0 0.00035 19.8 0.0 1.9 2 0 0 2 2 2 1 Beta-eliminating lyase SLA_LP_auto_ag PF05889.8 EXF80812.1 - 0.00049 18.6 0.3 0.0044 15.5 0.0 2.0 2 0 0 2 2 2 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Fungal_trans PF04082.13 EXF80812.1 - 0.0022 16.9 0.1 0.005 15.7 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain GDC-P PF02347.11 EXF80812.1 - 0.0022 16.7 0.0 0.0037 16.0 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 EXF80812.1 - 0.026 12.8 0.0 0.04 12.2 0.0 1.2 1 0 0 1 1 1 0 Methionine gamma-lyase Protoglobin PF11563.3 EXF80813.1 - 2.3e-56 189.8 0.1 2.8e-56 189.5 0.1 1.1 1 0 0 1 1 1 1 Protoglobin Reo_sigmaC PF04582.7 EXF80814.1 - 1.1 8.3 23.9 0.25 10.4 0.1 3.8 3 1 1 4 4 4 0 Reovirus sigma C capsid protein ABC1 PF03109.11 EXF80815.1 - 4.7e-25 87.8 0.2 2.4e-15 56.5 0.0 2.8 3 0 0 3 3 3 2 ABC1 family APH PF01636.18 EXF80815.1 - 0.0031 17.3 2.3 0.0075 16.0 0.1 2.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EXF80815.1 - 0.09 12.1 0.0 0.44 9.8 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Cyto_heme_lyase PF01265.12 EXF80816.1 - 1.4e-76 257.5 0.0 7.8e-76 255.0 0.0 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Tme5_EGF_like PF09064.5 EXF80819.1 - 0.048 13.2 4.4 0.11 12.1 3.0 1.7 1 0 0 1 1 1 0 Thrombomodulin like fifth domain, EGF-like PemK PF02452.12 EXF80821.1 - 0.019 15.1 0.0 0.036 14.2 0.0 1.4 1 1 0 1 1 1 0 PemK-like protein Phage_fiber_2 PF03406.8 EXF80821.1 - 0.041 13.5 0.2 0.066 12.8 0.1 1.3 1 0 0 1 1 1 0 Phage tail fibre repeat F-box-like PF12937.2 EXF80823.1 - 3.2e-09 36.3 0.1 1.4e-08 34.2 0.1 2.2 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EXF80823.1 - 0.042 13.5 1.3 1.6 8.4 0.2 3.0 2 0 0 2 2 2 0 F-box domain GCR1_C PF12550.3 EXF80824.1 - 1.1e-13 50.8 0.1 2.6e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Transcriptional activator of glycolytic enzymes DUF1664 PF07889.7 EXF80824.1 - 0.11 12.2 0.2 0.19 11.4 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Glyco_hydro_3 PF00933.16 EXF80825.1 - 3.6e-88 295.4 0.0 5.1e-88 294.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF80825.1 - 6.8e-49 166.4 0.0 2.1e-48 164.8 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF80825.1 - 2.1e-20 72.4 0.0 3.7e-20 71.6 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III-like domain Glyoxalase_2 PF12681.2 EXF80826.1 - 4.2e-14 53.0 0.0 5.6e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EXF80826.1 - 5.7e-11 42.4 0.0 1.5e-10 41.1 0.0 1.6 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EXF80826.1 - 2.4e-09 37.1 0.0 2.9e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.1 EXF80826.1 - 0.014 15.2 0.0 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 Glyoxalase-like domain Sugar_tr PF00083.19 EXF80827.1 - 1.9e-124 415.7 25.8 2.1e-124 415.5 17.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF80827.1 - 3.7e-25 88.3 40.7 6.7e-20 71.1 10.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily SBP_bac_11 PF13531.1 EXF80828.1 - 1.3e-07 31.5 0.0 1.8e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_6 PF13343.1 EXF80828.1 - 8.4e-07 28.5 0.3 2e-06 27.3 0.2 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.20 EXF80828.1 - 1.8e-05 24.6 2.5 3.6e-05 23.6 1.7 1.5 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein HsbA PF12296.3 EXF80829.1 - 3.8e-12 46.1 6.6 3.8e-12 46.1 4.6 1.4 2 0 0 2 2 2 1 Hydrophobic surface binding protein A DbpA PF03880.10 EXF80831.1 - 0.0079 15.8 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 DbpA RNA binding domain RRM_5 PF13893.1 EXF80831.1 - 0.054 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.11 EXF80832.1 - 1.7e-30 105.9 25.7 2.6e-30 105.3 17.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Pam17 PF08566.5 EXF80832.1 - 0.19 11.3 1.3 0.85 9.2 0.0 2.4 3 0 0 3 3 3 0 Mitochondrial import protein Pam17 DUF3054 PF11255.3 EXF80832.1 - 0.44 10.3 7.1 0.23 11.2 1.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3054) MAPEG PF01124.13 EXF80832.1 - 3.3 7.3 8.5 0.11 12.0 0.6 2.6 3 0 0 3 3 3 0 MAPEG family Sugar_tr PF00083.19 EXF80833.1 - 4.2e-88 295.8 24.5 5.1e-88 295.6 17.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF80833.1 - 4.4e-13 48.6 40.8 1.4e-10 40.3 22.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF946 PF06101.6 EXF80834.1 - 5.9e-12 44.3 2.9 3.1e-11 41.9 0.1 2.4 3 0 0 3 3 3 2 Plant protein of unknown function (DUF946) Foamy_virus_ENV PF03408.9 EXF80834.1 - 0.26 8.7 0.0 0.34 8.3 0.0 1.0 1 0 0 1 1 1 0 Foamy virus envelope protein Ank_2 PF12796.2 EXF80835.1 - 2.8e-35 120.4 1.3 7.4e-18 64.6 0.0 4.3 1 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EXF80835.1 - 1.9e-25 88.2 11.8 3.2e-08 33.5 0.4 6.0 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 EXF80835.1 - 3e-25 86.7 7.2 2.2e-05 24.0 0.0 7.9 8 0 0 8 8 8 4 Ankyrin repeat Ank_4 PF13637.1 EXF80835.1 - 2.3e-21 75.7 8.1 5.4e-09 36.3 0.0 6.5 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF80835.1 - 9.6e-19 65.6 3.9 0.00097 19.1 0.0 7.4 8 0 0 8 8 8 4 Ankyrin repeat NACHT PF05729.7 EXF80835.1 - 4.8e-07 29.5 0.1 1.2e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EXF80835.1 - 8e-05 22.6 0.1 0.00074 19.5 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EXF80835.1 - 0.011 16.0 0.0 0.94 9.7 0.0 2.7 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EXF80835.1 - 0.054 13.6 0.0 0.52 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain UBA_4 PF14555.1 EXF80835.1 - 0.066 12.7 0.1 0.2 11.2 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain DUF1619 PF07773.6 EXF80835.1 - 0.12 12.1 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1619) UPF0104 PF03706.8 EXF80837.1 - 0.0017 17.6 0.1 0.0023 17.2 0.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0104) DUF3814 PF12769.2 EXF80837.1 - 0.07 13.2 0.4 0.11 12.7 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3814) COesterase PF00135.23 EXF80838.1 - 4.8e-93 312.6 0.1 6.2e-93 312.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF80838.1 - 9.4e-06 25.3 0.0 2.9e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EXF80838.1 - 0.00031 20.0 0.0 0.00055 19.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EXF80838.1 - 0.0047 16.6 0.1 0.021 14.5 0.0 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase family Crystall_3 PF08964.5 EXF80840.1 - 0.0073 16.0 0.0 0.013 15.2 0.0 1.5 1 1 0 1 1 1 1 Beta/Gamma crystallin Crystall PF00030.14 EXF80840.1 - 0.053 13.4 0.1 0.076 12.9 0.0 1.3 1 0 0 1 1 1 0 Beta/Gamma crystallin Yeast-kill-tox PF09207.6 EXF80840.1 - 0.21 12.0 5.2 0.29 11.6 3.3 1.5 1 1 0 1 1 1 0 Yeast killer toxin Rtt106 PF08512.7 EXF80841.1 - 0.091 12.7 0.0 0.22 11.4 0.0 1.6 2 0 0 2 2 2 0 Histone chaperone Rttp106-like Glyco_hydr_30_2 PF14587.1 EXF80843.1 - 4.1e-19 68.7 8.3 2e-18 66.4 4.5 2.3 2 0 0 2 2 2 1 O-Glycosyl hydrolase family 30 DUF3530 PF12048.3 EXF80843.1 - 0.033 13.1 0.0 0.059 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) zf-C2H2 PF00096.21 EXF80846.1 - 0.064 13.6 1.6 0.12 12.8 1.1 1.4 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF80848.1 - 0.12 12.7 0.1 0.25 11.7 0.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger MscS_TM PF12794.2 EXF80851.1 - 0.82 8.2 3.8 1.2 7.6 2.6 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Aida_N PF08910.5 EXF80851.1 - 1.2 9.4 4.9 3.3 7.9 1.3 2.1 1 1 1 2 2 2 0 Aida N-terminus NinG PF05766.7 EXF80851.1 - 1.6 8.4 5.3 1.3 8.7 2.8 1.4 1 1 0 1 1 1 0 Bacteriophage Lambda NinG protein bZIP_1 PF00170.16 EXF80853.1 - 0.00016 21.5 6.8 0.00053 19.8 4.7 1.9 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EXF80853.1 - 0.0039 16.9 7.3 0.0039 16.9 5.1 2.0 2 1 1 3 3 3 1 Basic region leucine zipper HpcH_HpaI PF03328.9 EXF80854.1 - 4.8e-24 84.4 0.0 7.2e-24 83.8 0.0 1.5 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family DUF892 PF05974.7 EXF80855.1 - 0.0037 17.0 0.1 0.005 16.6 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF892) Ank_2 PF12796.2 EXF80856.1 - 3.2e-34 117.1 0.4 1.3e-13 51.0 0.2 3.8 2 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EXF80856.1 - 3e-25 86.7 13.9 0.012 15.3 0.0 8.1 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 EXF80856.1 - 1e-23 83.1 5.9 3.9e-07 30.3 0.2 6.0 5 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF80856.1 - 3.9e-21 73.0 5.7 0.16 12.3 0.0 9.0 9 0 0 9 9 9 6 Ankyrin repeat HET PF06985.6 EXF80856.1 - 4.7e-21 75.4 3.9 2.2e-17 63.5 0.1 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Ank_5 PF13857.1 EXF80856.1 - 2e-20 72.3 11.3 0.00029 20.9 0.2 8.0 3 2 5 8 8 8 7 Ankyrin repeats (many copies) GMC_oxred_N PF00732.14 EXF80857.1 - 4.1e-29 101.6 0.0 7.3e-29 100.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF80857.1 - 6.3e-22 78.4 0.6 1.4e-21 77.3 0.4 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EXF80857.1 - 6.7e-07 28.5 0.2 0.00015 20.8 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EXF80857.1 - 2.3e-06 26.9 0.0 0.00016 20.8 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF80857.1 - 1.3e-05 25.1 0.2 0.00032 20.6 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF80857.1 - 2e-05 23.2 1.2 0.00013 20.6 0.1 2.5 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_8 PF13450.1 EXF80857.1 - 0.00016 21.6 0.0 0.00057 19.8 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EXF80857.1 - 0.00026 19.9 2.2 0.00047 19.1 0.3 2.3 3 0 0 3 3 3 1 FAD binding domain GIDA PF01134.17 EXF80857.1 - 0.0023 16.8 0.1 0.0039 16.0 0.0 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.12 EXF80857.1 - 0.023 13.8 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 EXF80857.1 - 0.025 13.6 0.0 0.043 12.8 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EXF80857.1 - 0.051 13.9 0.4 0.27 11.6 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF80857.1 - 0.056 12.3 0.0 0.084 11.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EXF80857.1 - 0.082 11.5 0.1 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase MHC_I_2 PF14586.1 EXF80859.1 - 0.13 11.8 0.1 0.16 11.5 0.1 1.2 1 0 0 1 1 1 0 Class I Histocompatibility antigen, NKG2D ligand, domains 1 and 2 Actin PF00022.14 EXF80860.1 - 8e-79 264.8 0.0 1.2e-78 264.3 0.0 1.2 1 0 0 1 1 1 1 Actin F-box PF00646.28 EXF80860.1 - 4.4e-05 23.0 0.0 0.0001 21.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EXF80860.1 - 0.00032 20.3 0.0 0.00086 18.9 0.0 1.7 1 0 0 1 1 1 1 F-box-like DUF2177 PF09945.4 EXF80860.1 - 0.01 15.8 5.0 0.69 9.9 0.1 2.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2177) HTH_Tnp_1 PF01527.15 EXF80860.1 - 0.1 12.5 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 Transposase PRANC PF09372.5 EXF80860.1 - 0.21 11.5 0.0 0.42 10.6 0.0 1.5 1 0 0 1 1 1 0 PRANC domain V_ATPase_I PF01496.14 EXF80860.1 - 0.99 7.1 1.3 1.5 6.6 0.9 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Histone PF00125.19 EXF80862.1 - 6.1e-22 77.5 0.1 7.9e-22 77.1 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EXF80862.1 - 0.0001 22.2 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone R3H PF01424.17 EXF80864.1 - 1.3e-09 37.6 0.2 2.6e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 R3H domain RRM_6 PF14259.1 EXF80864.1 - 5.9e-07 29.3 0.1 1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EXF80864.1 - 1.6e-05 24.3 0.0 4.8e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF80864.1 - 0.00023 20.9 0.0 0.00042 20.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_2 PF04059.7 EXF80864.1 - 0.043 13.8 0.0 0.088 12.8 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif 2 Mre11_DNA_bind PF04152.9 EXF80865.1 - 3.4e-55 186.5 0.4 3.4e-55 186.5 0.2 1.8 2 0 0 2 2 2 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EXF80865.1 - 1.5e-23 83.2 2.6 2.2e-23 82.7 1.8 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EXF80865.1 - 5.6e-06 26.2 0.0 1.3e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Peptidase_M43 PF05572.8 EXF80866.1 - 1.4e-18 66.9 1.4 1.7e-18 66.7 0.2 1.7 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 EXF80866.1 - 1.3e-07 31.8 1.3 6.4e-07 29.5 0.1 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EXF80866.1 - 2.3e-06 28.1 0.2 4.6e-06 27.1 0.1 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EXF80866.1 - 1.7e-05 24.4 1.4 2.4e-05 23.9 0.9 1.3 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EXF80866.1 - 2.7e-05 24.1 3.1 2.9e-05 24.0 1.0 1.7 1 1 1 2 2 2 1 Metallo-peptidase family M12 Peptidase_M10 PF00413.19 EXF80866.1 - 0.0093 15.6 0.0 0.018 14.7 0.0 1.4 1 1 0 1 1 1 1 Matrixin Peptidase_M54 PF07998.6 EXF80866.1 - 0.011 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M57 PF12388.3 EXF80866.1 - 0.013 14.8 1.1 0.027 13.7 0.8 1.4 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase Peptidase_M66 PF10462.4 EXF80866.1 - 0.042 12.7 2.5 0.058 12.2 1.7 1.5 1 1 0 1 1 1 0 Peptidase M66 RecT PF03837.9 EXF80866.1 - 0.057 12.7 0.1 0.091 12.0 0.0 1.3 1 0 0 1 1 1 0 RecT family Metallopep PF12044.3 EXF80866.1 - 0.13 10.6 0.5 0.36 9.2 0.2 1.7 2 0 0 2 2 2 0 Putative peptidase family Beta-lactamase PF00144.19 EXF80867.1 - 1e-25 90.4 0.3 1.2e-24 86.9 0.2 2.0 1 1 0 1 1 1 1 Beta-lactamase Peptidase_M28 PF04389.12 EXF80868.1 - 7.7e-36 123.4 0.3 5.2e-35 120.7 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 EXF80868.1 - 1e-07 31.6 0.5 1.9e-07 30.7 0.1 1.6 1 1 1 2 2 2 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 EXF80868.1 - 0.013 14.7 0.1 0.26 10.4 0.0 2.2 2 0 0 2 2 2 0 Nicastrin Colipase PF01114.13 EXF80869.1 - 0.088 12.3 4.1 0.15 11.5 2.8 1.3 1 0 0 1 1 1 0 Colipase, N-terminal domain PepSY_2 PF13670.1 EXF80869.1 - 0.87 9.5 4.6 7.5 6.5 0.4 2.2 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Kelch_5 PF13854.1 EXF80870.1 - 2.4e-05 24.1 2.8 1 9.3 0.0 5.0 5 1 0 5 5 5 2 Kelch motif Kelch_6 PF13964.1 EXF80870.1 - 0.0063 16.6 5.9 9.4 6.6 0.1 5.8 6 0 0 6 6 6 1 Kelch motif Kelch_1 PF01344.20 EXF80870.1 - 0.13 11.7 6.8 0.6 9.7 0.0 4.2 4 0 0 4 4 4 0 Kelch motif Kelch_2 PF07646.10 EXF80870.1 - 0.72 9.7 9.9 0.95 9.3 0.3 4.9 4 2 0 4 4 4 0 Kelch motif Kelch_4 PF13418.1 EXF80870.1 - 2.8 7.7 14.8 1.4 8.7 0.1 5.5 5 2 1 6 6 6 0 Galactose oxidase, central domain MFS_1 PF07690.11 EXF80872.1 - 3.9e-19 68.5 27.7 2.9e-14 52.5 7.3 2.2 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF80872.1 - 9.9e-08 30.9 1.6 9.9e-08 30.9 1.1 2.7 2 2 1 3 3 3 2 Sugar (and other) transporter SH3_6 PF12913.2 EXF80872.1 - 0.032 13.4 0.1 0.076 12.2 0.1 1.7 1 0 0 1 1 1 0 SH3 domain of the SH3b1 type Pyr_redox_3 PF13738.1 EXF80873.1 - 1.1e-11 45.2 0.0 1.8e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF80873.1 - 1.2e-09 37.5 0.0 1.8e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EXF80873.1 - 3.7e-08 32.0 0.0 1.4e-07 30.1 0.0 1.7 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like DUF4064 PF13273.1 EXF80874.1 - 0.69 10.0 0.0 0.69 10.0 0.0 3.2 5 0 0 5 5 5 0 Protein of unknown function (DUF4064) Kinesin PF00225.18 EXF80875.1 - 3.8e-53 180.3 0.0 5.4e-53 179.8 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain COesterase PF00135.23 EXF80876.1 - 9.6e-107 357.8 0.0 1.3e-106 357.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF80876.1 - 1.1e-08 34.9 0.1 1.6e-07 31.0 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EXF80876.1 - 0.0039 16.4 0.2 0.0069 15.6 0.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family PAPS_reduct PF01507.14 EXF80877.1 - 7.7e-30 103.9 0.0 4.4e-21 75.4 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family adh_short PF00106.20 EXF80879.1 - 6.9e-23 81.3 0.1 8.9e-23 81.0 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF80879.1 - 2.7e-10 40.4 0.0 3.6e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF80879.1 - 2.6e-06 27.2 0.1 3.7e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF80879.1 - 5.7e-05 22.6 0.0 0.00017 21.0 0.0 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF80879.1 - 0.00019 21.4 0.4 0.00029 20.9 0.3 1.5 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EXF80879.1 - 0.00033 19.8 0.0 0.00039 19.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 EXF80879.1 - 0.00062 18.7 0.0 0.00099 18.0 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EXF80879.1 - 0.011 14.6 0.1 0.015 14.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain Abhydrolase_6 PF12697.2 EXF80882.1 - 3.8e-13 49.8 1.4 5.6e-13 49.2 1.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF80882.1 - 9.1e-12 44.9 0.0 1.9e-11 43.9 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family LIP PF03583.9 EXF80882.1 - 0.0027 16.9 0.8 0.69 9.0 0.2 2.1 2 0 0 2 2 2 2 Secretory lipase Peptidase_S9 PF00326.16 EXF80882.1 - 0.004 16.3 0.1 2.9 7.0 0.2 2.7 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EXF80882.1 - 0.0058 16.2 0.0 0.015 14.8 0.0 1.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold DLH PF01738.13 EXF80882.1 - 0.012 14.8 0.0 0.48 9.6 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.3 EXF80882.1 - 0.044 13.6 0.0 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 Putative lysophospholipase DUF3425 PF11905.3 EXF80883.1 - 1.1e-28 99.8 1.2 1.1e-28 99.7 0.3 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) Aldo_ket_red PF00248.16 EXF80884.1 - 5.2e-50 169.8 0.0 6.2e-50 169.5 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family FliJ PF02050.11 EXF80885.1 - 2.6 8.0 6.1 7.3 6.6 1.2 2.6 2 1 0 2 2 2 0 Flagellar FliJ protein MFS_1 PF07690.11 EXF80886.1 - 3.8e-41 140.9 47.8 1.2e-40 139.3 32.0 2.2 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF80886.1 - 9.1e-11 40.9 31.8 1.3e-10 40.5 10.9 3.5 1 1 1 3 3 3 3 Sugar (and other) transporter C9orf72-like PF15019.1 EXF80886.1 - 0.09 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 C9orf72-like protein family RdRP PF05183.7 EXF80887.1 - 4.5e-141 471.4 0.0 1.2e-140 469.9 0.0 1.7 1 1 0 1 1 1 1 RNA dependent RNA polymerase Abhydrolase_6 PF12697.2 EXF80888.1 - 2.6e-29 102.7 0.1 4e-29 102.1 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF80888.1 - 2.4e-13 50.1 0.0 4.6e-12 45.9 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Ndr PF03096.9 EXF80888.1 - 7.7e-11 40.9 0.0 1.1e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.2 EXF80888.1 - 2.2e-07 30.7 0.0 5.7e-07 29.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family EthD PF07110.6 EXF80888.1 - 5e-05 24.1 0.1 0.27 12.2 0.0 2.9 2 0 0 2 2 2 2 EthD domain DUF4286 PF14114.1 EXF80888.1 - 0.0044 17.2 0.0 0.95 9.7 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4286) Esterase PF00756.15 EXF80888.1 - 0.069 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Como_LCP PF02247.11 EXF80888.1 - 0.11 10.8 0.0 0.17 10.2 0.0 1.2 1 0 0 1 1 1 0 Large coat protein Glyco_hydro_61 PF03443.9 EXF80889.1 - 6.5e-73 245.1 1.8 8.1e-73 244.8 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Serglycin PF04360.7 EXF80889.1 - 0.0012 18.6 6.4 0.0021 17.8 4.5 1.4 1 0 0 1 1 1 1 Serglycin Zn_clus PF00172.13 EXF80890.1 - 9e-06 25.5 12.2 1.6e-05 24.6 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EXF80894.1 - 4.8e-20 71.5 3.4 5.4e-20 71.4 2.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter DUF809 PF05663.6 EXF80894.1 - 0.13 12.1 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF809) DUF4342 PF14242.1 EXF80894.1 - 0.75 9.6 2.9 24 4.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4342) Sulfatase PF00884.18 EXF80895.1 - 1.6e-69 234.4 0.0 2e-69 234.1 0.0 1.1 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EXF80895.1 - 0.00037 19.9 0.0 0.017 14.4 0.0 2.6 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase_C PF14707.1 EXF80895.1 - 0.0044 17.3 0.6 0.17 12.2 0.4 2.4 1 1 0 1 1 1 1 C-terminal region of aryl-sulfatase DUF229 PF02995.12 EXF80895.1 - 0.032 12.6 0.0 0.047 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF229) TILa PF12714.2 EXF80897.1 - 0.097 12.4 0.6 0.14 11.9 0.4 1.2 1 0 0 1 1 1 0 TILa domain DUF2235 PF09994.4 EXF80898.1 - 6.4e-24 84.7 0.0 6.7e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Abhydrolase_5 PF12695.2 EXF80898.1 - 0.029 14.1 0.0 0.03 14.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF80898.1 - 0.079 12.8 0.0 0.098 12.5 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family FSH1 PF03959.8 EXF80898.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) p450 PF00067.17 EXF80899.1 - 6.3e-36 123.8 0.0 1.4e-35 122.7 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 RTA1 PF04479.8 EXF80899.1 - 6.1e-23 81.4 0.3 1.1e-21 77.4 0.2 2.2 1 1 0 1 1 1 1 RTA1 like protein NARP1 PF12569.3 EXF80899.1 - 0.018 13.8 6.9 0.034 12.8 3.8 1.8 2 0 0 2 2 2 0 NMDA receptor-regulated protein 1 DUF3899 PF13038.1 EXF80899.1 - 0.024 14.7 1.1 1.3 9.2 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) YkyA PF10368.4 EXF80899.1 - 0.044 13.1 5.4 0.07 12.4 3.8 1.2 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein OAD_gamma PF04277.8 EXF80899.1 - 1.1 9.7 5.6 1.5 9.2 0.5 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Nop25 PF09805.4 EXF80899.1 - 7.3 6.6 19.8 12 5.9 13.7 1.2 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Iso_dh PF00180.15 EXF80900.1 - 1.2e-107 359.8 0.0 1.4e-107 359.6 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Polysacc_synt_2 PF02719.10 EXF80900.1 - 0.19 10.5 0.0 0.35 9.7 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Aminotran_4 PF01063.14 EXF80901.1 - 1.8e-18 66.8 0.0 2.2e-18 66.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Aconitase PF00330.15 EXF80902.1 - 9e-66 222.2 0.0 9e-43 146.4 0.0 2.3 1 1 1 2 2 2 2 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EXF80902.1 - 8.4e-12 45.3 0.0 1.8e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.8 EXF80902.1 - 0.00016 21.1 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 Aconitate hydratase 2 N-terminus Ank_2 PF12796.2 EXF80903.1 - 9.4e-34 115.6 5.7 1e-19 70.6 0.6 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EXF80903.1 - 8.7e-23 78.9 3.1 2.8e-08 33.1 0.4 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.1 EXF80903.1 - 1e-17 62.4 0.2 4.4e-06 26.4 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EXF80903.1 - 7.4e-15 55.0 0.1 6.9e-09 35.9 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF80903.1 - 1.6e-13 50.3 0.2 1.3e-05 25.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) AKAP28 PF14469.1 EXF80903.1 - 0.021 14.4 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 28 kDa A-kinase anchor p450 PF00067.17 EXF80904.1 - 1.7e-53 181.8 0.0 2.2e-53 181.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Polysacc_deac_1 PF01522.16 EXF80905.1 - 1.3e-14 53.9 0.0 2e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EXF80905.1 - 0.0042 16.5 0.0 0.0064 15.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2334) Aminotran_5 PF00266.14 EXF80906.1 - 1.4e-56 191.9 0.0 1.9e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EXF80906.1 - 3.5e-06 25.5 0.0 4.3e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EXF80906.1 - 2.2e-05 23.5 0.1 3.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EXF80906.1 - 3.1e-05 23.1 0.2 7.2e-05 21.9 0.1 1.5 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family HMGL-like PF00682.14 EXF80907.1 - 5.2e-51 173.5 0.0 7.3e-51 173.1 0.0 1.2 1 0 0 1 1 1 1 HMGL-like AP_endonuc_2 PF01261.19 EXF80907.1 - 0.011 15.0 0.0 0.02 14.2 0.0 1.5 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel MFS_1 PF07690.11 EXF80908.1 - 2.2e-41 141.7 48.7 4.3e-41 140.7 32.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily AMP-binding PF00501.23 EXF80909.1 - 0 1067.7 0.0 2.9e-86 289.4 0.0 4.3 4 0 0 4 4 4 4 AMP-binding enzyme Condensation PF00668.15 EXF80909.1 - 2.8e-154 512.3 0.0 2.3e-42 144.8 0.0 5.5 5 0 0 5 5 5 5 Condensation domain PP-binding PF00550.20 EXF80909.1 - 3.5e-50 168.1 0.1 2.6e-11 43.6 0.0 5.2 4 0 0 4 4 4 4 Phosphopantetheine attachment site AATase PF07247.7 EXF80909.1 - 1.7 7.1 0.0 58 2.0 0.0 2.3 2 0 0 2 2 2 0 Alcohol acetyltransferase Fungal_trans_2 PF11951.3 EXF80910.1 - 2.3e-13 49.5 3.1 7.3e-13 47.8 2.1 1.7 1 1 0 1 1 1 1 Fungal specific transcription factor domain PEP_mutase PF13714.1 EXF80911.1 - 2.1e-49 167.9 0.7 3.8e-49 167.0 0.3 1.5 1 1 1 2 2 2 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EXF80911.1 - 5.6e-15 54.5 0.1 8.1e-15 54.0 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family Pantoate_transf PF02548.10 EXF80911.1 - 0.0032 16.6 0.0 0.021 13.9 0.0 2.0 2 0 0 2 2 2 1 Ketopantoate hydroxymethyltransferase DAHP_synth_1 PF00793.15 EXF80911.1 - 0.016 13.9 0.0 0.75 8.4 0.0 2.5 2 0 0 2 2 2 0 DAHP synthetase I family MFS_1 PF07690.11 EXF80913.1 - 2.3e-28 98.9 25.6 2.6e-28 98.7 17.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily TFIID_30kDa PF03540.8 EXF80914.1 - 1e-25 89.3 0.3 1.8e-25 88.5 0.2 1.4 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit EBV-NA1 PF02905.9 EXF80914.1 - 0.12 11.8 0.2 0.2 11.1 0.1 1.4 1 0 0 1 1 1 0 Epstein Barr virus nuclear antigen-1, DNA-binding domain Mucin PF01456.12 EXF80914.1 - 2.4 7.9 7.7 3.8 7.2 5.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Ribosomal_S19 PF00203.16 EXF80915.1 - 7.7e-24 83.1 0.0 1.2e-23 82.5 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein S19 Cellulase PF00150.13 EXF80916.1 - 2.7e-48 164.5 2.5 3.5e-48 164.2 1.7 1.0 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4038 PF13204.1 EXF80916.1 - 0.019 14.2 0.2 0.019 14.2 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4038) Pho88 PF10032.4 EXF80917.1 - 2.4e-79 265.0 0.2 2.7e-79 264.8 0.1 1.0 1 0 0 1 1 1 1 Phosphate transport (Pho88) XPA_C PF05181.7 EXF80918.1 - 3.2e-28 97.0 4.5 4.5e-28 96.5 2.2 2.1 2 0 0 2 2 2 1 XPA protein C-terminus XPA_N PF01286.13 EXF80918.1 - 0.0024 17.5 3.1 0.0024 17.5 2.2 1.9 2 0 0 2 2 2 1 XPA protein N-terminal ArfGap PF01412.13 EXF80918.1 - 0.81 9.4 3.8 0.26 11.0 0.3 1.8 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Striatin PF08232.7 EXF80919.1 - 1.8e-36 125.4 1.0 1.8e-36 125.4 0.7 2.5 2 1 0 2 2 2 1 Striatin family WD40 PF00400.27 EXF80919.1 - 1.2e-30 104.2 19.1 2.2e-08 33.6 0.0 7.5 7 1 0 7 7 7 5 WD domain, G-beta repeat MNSV_P7B PF06692.6 EXF80919.1 - 0.073 12.8 0.0 0.38 10.5 0.0 2.2 1 0 0 1 1 1 0 Melon necrotic spot virus P7B protein Cytochrom_D1 PF02239.11 EXF80919.1 - 0.11 10.7 0.0 0.26 9.5 0.0 1.5 2 0 0 2 2 2 0 Cytochrome D1 heme domain PAT1 PF09770.4 EXF80919.1 - 0.18 10.0 36.5 0.26 9.4 25.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BC10 PF06726.7 EXF80921.1 - 6.9e-18 64.4 11.4 1.2e-17 63.6 7.9 1.4 1 0 0 1 1 1 1 Bladder cancer-related protein BC10 LicD PF04991.8 EXF80924.1 - 6.2e-37 127.7 8.7 2.4e-35 122.4 6.0 2.1 1 1 0 1 1 1 1 LicD family WLM PF08325.5 EXF80925.1 - 6.6e-44 150.0 0.7 8e-44 149.7 0.0 1.4 2 0 0 2 2 2 1 WLM domain DUF45 PF01863.12 EXF80925.1 - 6e-05 22.9 0.8 0.00013 21.7 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function DUF45 Reprolysin_5 PF13688.1 EXF80925.1 - 0.026 14.4 0.9 0.064 13.1 0.6 1.8 1 1 0 1 1 1 0 Metallo-peptidase family M12 SprT-like PF10263.4 EXF80925.1 - 0.068 12.8 0.4 0.11 12.1 0.3 1.4 1 0 0 1 1 1 0 SprT-like family Peptidase_MA_2 PF13485.1 EXF80925.1 - 0.096 12.7 0.2 0.2 11.7 0.2 1.5 1 0 0 1 1 1 0 Peptidase MA superfamily ubiquitin PF00240.18 EXF80925.1 - 0.12 11.7 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin family ER_lumen_recept PF00810.13 EXF80926.1 - 1e-53 181.7 9.2 1.6e-53 181.1 6.4 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor Post_transc_reg PF13797.1 EXF80926.1 - 0.11 12.1 0.1 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 Post-transcriptional regulator PQ-loop PF04193.9 EXF80926.1 - 3.6 7.1 14.4 0.55 9.8 0.7 3.2 4 0 0 4 4 4 0 PQ loop repeat DUF3584 PF12128.3 EXF80927.1 - 0.72 7.1 26.2 1 6.6 18.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Rifin_STEVOR PF02009.11 EXF80927.1 - 0.82 9.2 18.6 2 7.9 12.6 1.7 1 1 0 1 1 1 0 Rifin/stevor family DUF2232 PF09991.4 EXF80927.1 - 2.1 7.2 6.2 6.7 5.6 0.1 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) Bd3614_N PF14442.1 EXF80928.1 - 0.055 13.4 1.1 0.096 12.6 0.8 1.3 1 0 0 1 1 1 0 Bd3614-like deaminase N-terminal ROKNT PF08067.6 EXF80928.1 - 0.21 11.4 2.1 0.45 10.4 1.4 1.5 1 0 0 1 1 1 0 ROKNT (NUC014) domain Ank_2 PF12796.2 EXF80929.1 - 1.5e-17 63.6 0.5 4.5e-10 39.7 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EXF80929.1 - 1.4e-13 50.9 3.7 3.6e-07 30.5 0.0 5.1 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.25 EXF80929.1 - 1.4e-13 49.8 2.5 2.5e-05 23.8 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EXF80929.1 - 2.2e-11 43.6 6.7 3.3e-08 33.5 0.2 4.5 4 1 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF80929.1 - 7.9e-07 28.7 4.9 0.11 12.7 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat Pec_lyase_C PF00544.14 EXF80930.1 - 9.7e-17 61.0 7.8 2.3e-16 59.8 5.4 1.6 1 1 0 1 1 1 1 Pectate lyase MFS_1 PF07690.11 EXF80931.1 - 1.2e-38 132.7 17.9 1.2e-38 132.7 12.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF997 PF06196.7 EXF80931.1 - 0.02 14.3 0.5 0.064 12.7 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF997) Lyase_1 PF00206.15 EXF80932.1 - 4.3e-47 160.8 0.0 8e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EXF80932.1 - 6.3e-20 70.9 0.1 2.5e-19 69.0 0.1 2.0 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminus Fungal_trans_2 PF11951.3 EXF80933.1 - 3.9e-11 42.1 0.5 1.8e-10 39.9 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EXF80934.1 - 4.6e-28 97.8 0.1 7e-28 97.2 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF80934.1 - 0.0098 15.7 2.7 0.018 14.9 1.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 EXF80935.1 - 1.9e-53 181.1 0.0 2.3e-53 180.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family Death PF00531.17 EXF80935.1 - 0.00059 19.5 0.0 1.7 8.4 0.0 3.4 2 1 1 3 3 3 3 Death domain MFS_1 PF07690.11 EXF80936.1 - 2.4e-19 69.2 27.0 2.4e-19 69.2 18.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF80936.1 - 7.5e-05 21.4 9.7 7.5e-05 21.4 6.7 2.8 1 1 1 3 3 3 1 Sugar (and other) transporter DUF3938 PF13074.1 EXF80936.1 - 0.036 13.9 0.0 0.12 12.1 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) DUF4272 PF14094.1 EXF80936.1 - 0.1 11.6 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4272) PHO4 PF01384.15 EXF80938.1 - 3.5e-87 292.1 14.7 4e-87 291.9 10.2 1.0 1 0 0 1 1 1 1 Phosphate transporter family Tannase PF07519.6 EXF80939.1 - 1.4e-88 297.7 0.6 1.6e-88 297.5 0.4 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Peptidase_S9 PF00326.16 EXF80939.1 - 2.7e-08 33.3 0.0 0.0015 17.7 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EXF80939.1 - 6.9e-07 29.3 0.2 3.8e-06 26.9 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF80939.1 - 4.7e-05 23.1 0.5 0.33 10.7 0.2 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF80939.1 - 0.0071 15.9 0.1 0.0071 15.9 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Gcd10p PF04189.8 EXF80940.1 - 8.2e-74 248.4 0.0 2e-63 214.3 0.0 2.3 2 0 0 2 2 2 2 Gcd10p family Mucin PF01456.12 EXF80940.1 - 2.1 8.1 12.7 3.9 7.2 8.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein P21-Arc PF04062.9 EXF80941.1 - 1.6e-78 262.4 0.0 1.8e-78 262.3 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Hormone_3 PF00159.13 EXF80941.1 - 0.0062 16.5 0.5 0.013 15.4 0.4 1.5 1 0 0 1 1 1 1 Pancreatic hormone peptide COesterase PF00135.23 EXF80943.1 - 1.8e-89 300.9 0.0 2.4e-89 300.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF80943.1 - 3e-06 26.9 0.5 3.2e-05 23.5 0.3 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EXF80943.1 - 0.014 14.6 0.4 0.024 13.8 0.3 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Fungal_trans_2 PF11951.3 EXF80944.1 - 1.4e-08 33.7 0.1 1.1e-06 27.5 0.0 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF80944.1 - 6.7e-06 25.9 11.5 1.2e-05 25.1 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FlgM PF04316.8 EXF80944.1 - 0.022 14.6 0.0 0.072 13.0 0.0 1.8 1 0 0 1 1 1 0 Anti-sigma-28 factor, FlgM VPS28 PF03997.7 EXF80945.1 - 0.048 13.2 0.8 0.066 12.8 0.5 1.2 1 0 0 1 1 1 0 VPS28 protein FliD_N PF02465.13 EXF80945.1 - 0.06 13.7 12.4 0.12 12.7 8.6 1.5 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus CFEM PF05730.6 EXF80945.1 - 0.2 11.4 13.8 0.43 10.4 9.5 1.8 1 1 0 1 1 1 0 CFEM domain Macoilin PF09726.4 EXF80945.1 - 1.9 6.6 6.6 2 6.6 4.5 1.1 1 0 0 1 1 1 0 Transmembrane protein DNA_pol_viral_N PF00242.12 EXF80945.1 - 3.1 6.7 4.9 3.6 6.5 3.4 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain Herpes_capsid PF06112.6 EXF80945.1 - 9.1 6.3 19.4 13 5.8 13.5 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Ion_trans PF00520.26 EXF80946.1 - 1.2e-07 31.2 5.9 2.6e-07 30.0 4.1 1.5 2 0 0 2 2 2 1 Ion transport protein RRM_1 PF00076.17 EXF80947.1 - 6.6e-17 60.9 0.0 1e-16 60.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF80947.1 - 4.4e-15 55.4 0.0 7.8e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF80947.1 - 5e-05 23.0 0.0 8.8e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) V_ATPase_I PF01496.14 EXF80947.1 - 0.0036 15.2 0.4 0.0043 15.0 0.3 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family IncA PF04156.9 EXF80947.1 - 0.03 13.9 0.9 0.036 13.6 0.6 1.1 1 0 0 1 1 1 0 IncA protein Filament PF00038.16 EXF80947.1 - 0.046 13.1 4.0 0.058 12.8 2.8 1.1 1 0 0 1 1 1 0 Intermediate filament protein APG6 PF04111.7 EXF80947.1 - 0.066 12.2 1.2 0.076 12.0 0.8 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 EXF80947.1 - 0.13 12.6 0.9 0.18 12.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF972) EMP24_GP25L PF01105.19 EXF80947.1 - 0.21 11.2 1.7 0.3 10.8 1.2 1.1 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF904 PF06005.7 EXF80947.1 - 0.33 11.2 4.6 0.55 10.5 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF904) DivIC PF04977.10 EXF80947.1 - 1.1 8.8 4.7 1.7 8.2 3.3 1.2 1 0 0 1 1 1 0 Septum formation initiator HECT PF00632.20 EXF80948.1 - 2.4e-91 306.2 0.0 3.3e-91 305.7 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) WW PF00397.21 EXF80948.1 - 2.1e-33 113.8 21.9 1.7e-11 43.7 4.6 3.7 3 0 0 3 3 3 3 WW domain C2 PF00168.25 EXF80948.1 - 4.6e-16 58.4 0.1 1.3e-15 56.9 0.1 1.8 1 0 0 1 1 1 1 C2 domain Oxidored_q6 PF01058.17 EXF80949.1 - 1.3e-22 79.8 0.1 2e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit p450 PF00067.17 EXF80951.1 - 5.1e-50 170.3 0.0 1.1e-49 169.2 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Ceramidase_alk PF04734.8 EXF80952.1 - 1.6e-279 928.5 0.0 2e-279 928.1 0.0 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase SBP56 PF05694.6 EXF80952.1 - 0.22 10.0 0.0 1.5 7.2 0.0 2.3 1 1 0 1 1 1 0 56kDa selenium binding protein (SBP56) Cupin_1 PF00190.17 EXF80953.1 - 3.7e-31 107.5 0.0 9.1e-15 54.3 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EXF80953.1 - 2.1e-23 81.5 1.0 2.9e-13 49.1 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EXF80953.1 - 4.3e-07 29.2 0.1 0.0052 16.1 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EXF80953.1 - 8.5e-05 22.2 0.0 0.42 10.2 0.0 2.2 2 0 0 2 2 2 2 Cupin AraC_binding PF02311.14 EXF80953.1 - 0.0013 18.3 0.1 0.14 11.8 0.0 2.6 3 0 0 3 3 3 1 AraC-like ligand binding domain VacJ PF04333.8 EXF80953.1 - 0.13 11.6 0.1 0.37 10.1 0.0 1.7 2 0 0 2 2 2 0 VacJ like lipoprotein Endosulfine PF04667.12 EXF80954.1 - 8.5e-22 76.9 0.0 1.4e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region UPF0160 PF03690.8 EXF80955.1 - 5.6e-120 400.5 0.0 6.4e-120 400.3 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) Ino80_Iec3 PF14612.1 EXF80956.1 - 9.2e-62 209.1 12.7 1.6e-33 116.7 1.0 2.6 2 1 1 3 3 3 2 IEC3 subunit of the Ino80 complex, chromatin re-modelling Iso_dh PF00180.15 EXF80957.1 - 1.8e-72 244.2 0.0 2.1e-72 243.9 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase RNase_PH PF01138.16 EXF80959.1 - 1.2e-15 57.9 0.0 2.3e-15 57.0 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EXF80959.1 - 0.03 14.2 0.0 0.069 13.0 0.0 1.5 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Cytochrom_C PF00034.16 EXF80961.1 - 2.7e-11 44.1 0.1 4e-11 43.5 0.1 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EXF80961.1 - 3.1e-09 36.8 2.8 1.7e-08 34.4 1.9 1.8 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EXF80961.1 - 0.0071 15.7 2.2 0.044 13.2 1.4 2.2 1 1 0 1 1 1 1 Cytochrome c-550 domain AAA PF00004.24 EXF80962.1 - 1.6e-64 216.0 0.0 2.2e-45 154.1 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EXF80962.1 - 9.2e-10 38.8 3.1 4.6e-05 23.4 0.0 4.2 3 2 1 4 4 4 2 AAA ATPase domain AAA_22 PF13401.1 EXF80962.1 - 5.4e-09 36.2 0.1 0.0028 17.8 0.0 5.3 3 2 1 4 4 3 1 AAA domain AAA_17 PF13207.1 EXF80962.1 - 1.2e-08 35.7 0.8 0.0049 17.6 0.0 3.4 3 2 0 3 3 2 2 AAA domain AAA_5 PF07728.9 EXF80962.1 - 2.9e-08 33.5 0.0 0.0017 18.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EXF80962.1 - 2.7e-07 29.8 0.8 0.00043 19.4 0.0 3.2 4 0 0 4 4 4 2 Zeta toxin AAA_18 PF13238.1 EXF80962.1 - 2.7e-07 30.9 1.3 0.0033 17.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.1 EXF80962.1 - 3.4e-06 26.9 0.0 0.0025 17.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EXF80962.1 - 5e-06 25.7 0.0 0.0004 19.5 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EXF80962.1 - 5.8e-06 25.9 0.2 0.034 13.9 0.0 3.5 3 0 0 3 3 3 2 Part of AAA domain AAA_14 PF13173.1 EXF80962.1 - 7.6e-06 25.8 0.0 0.0022 17.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain Sigma54_activ_2 PF14532.1 EXF80962.1 - 1.4e-05 25.2 0.0 0.076 13.0 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 EXF80962.1 - 1.5e-05 24.4 0.7 3.6 6.9 0.0 4.4 2 2 1 4 4 4 1 AAA domain AAA_28 PF13521.1 EXF80962.1 - 2.4e-05 24.3 1.2 0.37 10.7 0.0 3.6 3 1 0 3 3 3 2 AAA domain IstB_IS21 PF01695.12 EXF80962.1 - 5.8e-05 22.5 0.0 0.023 14.1 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.9 EXF80962.1 - 0.00014 21.7 0.0 0.0015 18.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 EXF80962.1 - 0.00035 20.7 0.0 0.045 13.9 0.0 2.7 2 0 0 2 2 2 1 RNA helicase Mg_chelatase PF01078.16 EXF80962.1 - 0.00051 19.2 0.1 0.096 11.8 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EXF80962.1 - 0.0013 17.6 0.0 0.65 8.8 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Sigma54_activat PF00158.21 EXF80962.1 - 0.0013 18.2 0.0 0.63 9.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.1 EXF80962.1 - 0.0016 18.0 0.0 1.1 8.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.10 EXF80962.1 - 0.0028 16.4 0.0 0.26 9.9 0.0 2.2 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_11 PF13086.1 EXF80962.1 - 0.0048 16.5 0.5 1.1 8.8 0.0 2.9 3 0 0 3 3 3 1 AAA domain ATP-synt_ab PF00006.20 EXF80962.1 - 0.0052 16.3 0.0 0.46 9.9 0.0 2.3 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain TIP49 PF06068.8 EXF80962.1 - 0.0057 15.4 0.0 0.23 10.1 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus NACHT PF05729.7 EXF80962.1 - 0.0077 15.9 0.1 2.7 7.6 0.0 3.4 3 1 0 3 3 3 1 NACHT domain Vps4_C PF09336.5 EXF80962.1 - 0.0091 15.8 0.1 1 9.3 0.0 3.1 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain Arch_ATPase PF01637.13 EXF80962.1 - 0.013 15.1 0.0 6 6.4 0.0 3.2 2 1 1 3 3 3 0 Archaeal ATPase ABC_tran PF00005.22 EXF80962.1 - 0.023 14.9 0.0 2.2 8.5 0.0 2.8 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.17 EXF80962.1 - 0.026 13.3 0.0 0.1 11.4 0.0 2.0 3 0 0 3 3 3 0 NB-ARC domain AAA_3 PF07726.6 EXF80962.1 - 0.042 13.4 0.0 1.7 8.2 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EXF80962.1 - 0.049 13.3 0.0 13 5.4 0.0 2.5 2 0 0 2 2 2 0 NTPase Viral_helicase1 PF01443.13 EXF80962.1 - 0.071 12.6 0.0 1.2 8.6 0.0 2.3 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase IPT PF01745.11 EXF80962.1 - 0.4 9.7 1.3 13 4.8 0.0 2.7 3 0 0 3 3 3 0 Isopentenyl transferase CRM1_C PF08767.6 EXF80963.1 - 2e-133 444.2 4.1 2e-133 444.2 2.8 2.8 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.7 EXF80963.1 - 1.9e-41 141.4 6.4 1.9e-41 141.4 4.5 4.3 5 1 0 5 5 5 1 Exportin 1-like protein IBN_N PF03810.14 EXF80963.1 - 2.8e-11 43.1 0.2 9.4e-11 41.4 0.1 2.0 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF3385 PF11865.3 EXF80963.1 - 0.0038 17.1 0.2 0.18 11.7 0.0 3.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) HD_assoc PF13286.1 EXF80963.1 - 0.038 14.2 1.3 11 6.4 0.1 4.0 4 0 0 4 4 4 0 Phosphohydrolase-associated domain Vac14_Fab1_bd PF12755.2 EXF80963.1 - 0.058 13.7 5.4 3.2 8.2 0.0 5.4 6 0 0 6 6 6 0 Vacuolar 14 Fab1-binding region C8 PF08742.6 EXF80963.1 - 0.16 12.2 1.3 1.1 9.5 0.0 2.8 3 0 0 3 3 3 0 C8 domain Aminotran_5 PF00266.14 EXF80964.1 - 1.8e-25 89.4 0.0 2.4e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V B12-binding PF02310.14 EXF80964.1 - 0.00015 21.5 0.2 0.0028 17.5 0.0 2.5 2 1 1 3 3 3 1 B12 binding domain DUF521 PF04412.8 EXF80964.1 - 0.017 13.6 0.0 0.026 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF521) RusA PF05866.6 EXF80964.1 - 0.092 13.1 0.3 0.17 12.2 0.2 1.5 1 1 0 1 1 1 0 Endodeoxyribonuclease RusA Metallophos_2 PF12850.2 EXF80965.1 - 4.7e-13 49.2 0.0 6e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Shugoshin_C PF07557.6 EXF80966.1 - 7.5e-13 47.6 7.0 7.2e-12 44.5 4.8 2.9 1 0 0 1 1 1 1 Shugoshin C terminus Shugoshin_N PF07558.6 EXF80966.1 - 0.42 10.3 3.0 1 9.1 1.5 2.1 1 1 1 2 2 2 0 Shugoshin N-terminal coiled-coil region DASH_Dad2 PF08654.5 EXF80967.1 - 6.9e-33 112.7 1.2 1.1e-32 112.1 0.8 1.3 1 0 0 1 1 1 1 DASH complex subunit Dad2 AAA_27 PF13514.1 EXF80967.1 - 0.0054 14.4 1.3 0.0059 14.3 0.9 1.0 1 0 0 1 1 1 1 AAA domain Seryl_tRNA_N PF02403.17 EXF80967.1 - 0.025 14.5 0.2 0.052 13.5 0.1 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain HAUS2 PF15003.1 EXF80967.1 - 0.026 13.6 0.1 0.037 13.1 0.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 COesterase PF00135.23 EXF80969.1 - 2.2e-80 270.9 0.0 2.9e-80 270.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF80969.1 - 1.9e-05 24.3 2.7 3.1e-05 23.6 0.3 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold SKG6 PF08693.5 EXF80970.1 - 5.3e-11 41.6 0.9 1.2e-10 40.5 0.6 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EXF80970.1 - 0.0029 17.1 0.1 0.0077 15.7 0.0 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF4448) CcmD PF04995.9 EXF80970.1 - 0.015 15.0 0.7 0.027 14.1 0.5 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF912 PF06024.7 EXF80970.1 - 0.068 13.2 0.1 4.7 7.3 0.0 2.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 EXF80970.1 - 0.083 12.5 6.8 0.67 9.5 0.0 2.0 1 1 0 2 2 2 0 Rifin/stevor family IER PF05760.7 EXF80970.1 - 0.14 12.0 11.2 0.23 11.3 7.8 1.5 1 0 0 1 1 1 0 Immediate early response protein (IER) TMEM154 PF15102.1 EXF80970.1 - 1.7 8.3 22.2 1.3e+03 -1.1 15.4 3.1 1 1 0 1 1 1 0 TMEM154 protein family OB_NTP_bind PF07717.11 EXF80972.1 - 6.1e-24 84.0 0.1 1.2e-23 83.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EXF80972.1 - 1.9e-20 72.8 1.1 2.8e-20 72.2 0.0 1.9 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EXF80972.1 - 3.3e-12 46.1 0.0 8.7e-12 44.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EXF80972.1 - 2.4e-05 24.4 0.1 7.1e-05 22.9 0.1 1.8 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EXF80972.1 - 0.00015 21.3 0.8 0.00046 19.7 0.5 1.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_23 PF13476.1 EXF80972.1 - 0.00029 21.2 1.5 0.0063 16.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EXF80972.1 - 0.00061 19.4 0.1 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EXF80972.1 - 0.0076 15.1 0.1 0.017 14.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein Zeta_toxin PF06414.7 EXF80972.1 - 0.0085 15.2 1.5 0.018 14.1 0.1 2.2 2 1 0 2 2 2 1 Zeta toxin Glycos_transf_N PF04413.11 EXF80972.1 - 0.026 13.6 0.0 0.053 12.6 0.0 1.4 1 0 0 1 1 1 0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) AAA_29 PF13555.1 EXF80972.1 - 0.043 13.3 0.0 0.14 11.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_14 PF13173.1 EXF80972.1 - 0.054 13.3 0.6 7 6.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EXF80972.1 - 0.11 11.9 0.0 0.33 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Androgen_recep PF02166.11 EXF80972.1 - 0.22 10.3 1.4 0.37 9.5 0.9 1.3 1 0 0 1 1 1 0 Androgen receptor CUE PF02845.11 EXF80973.1 - 1.1e-12 47.1 0.0 2e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 CUE domain Ank_2 PF12796.2 EXF80974.1 - 6.4e-42 141.7 9.0 2.8e-13 50.0 0.4 5.1 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) SPX PF03105.14 EXF80974.1 - 2.2e-28 99.8 12.5 4.4e-15 56.2 3.1 2.3 1 1 1 2 2 2 2 SPX domain Ank_4 PF13637.1 EXF80974.1 - 4.4e-26 90.7 7.4 8e-08 32.6 0.0 6.5 4 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.25 EXF80974.1 - 2.3e-24 83.8 12.1 5.6e-05 22.7 0.0 8.3 8 0 0 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 EXF80974.1 - 2.3e-18 65.7 12.3 0.0023 18.1 0.0 8.4 2 1 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF80974.1 - 8.3e-17 59.6 9.2 0.0059 16.7 0.0 8.5 9 0 0 9 9 9 3 Ankyrin repeat GDPD PF03009.12 EXF80974.1 - 6.5e-08 32.3 0.0 2.7e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family DRAT PF07357.6 EXF80974.1 - 0.094 11.8 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) Coa1 PF08695.5 EXF80976.1 - 4.5e-40 135.7 0.0 6.1e-40 135.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 Ribosomal_L3 PF00297.17 EXF80977.1 - 1.5e-34 119.5 2.1 5.9e-34 117.6 1.5 1.8 1 1 0 1 1 1 1 Ribosomal protein L3 Complex1_LYR PF05347.10 EXF80978.1 - 3e-06 26.9 1.7 5.6e-06 26.0 1.0 1.6 1 1 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EXF80978.1 - 0.002 18.2 2.4 0.003 17.7 1.6 1.5 1 1 0 1 1 1 1 Complex1_LYR-like DUF3798 PF12683.2 EXF80978.1 - 0.017 14.2 0.0 0.021 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3798) Complex1_LYR_2 PF13233.1 EXF80978.1 - 0.066 13.6 1.4 0.12 12.8 1.0 1.4 1 1 0 1 1 1 0 Complex1_LYR-like Mito_carr PF00153.22 EXF80979.1 - 1.7e-44 149.4 6.7 5.3e-17 61.3 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein DUF2293 PF10056.4 EXF80980.1 - 4.8e-28 96.9 0.3 1.4e-27 95.4 0.2 1.8 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2293) Snf7 PF03357.16 EXF80981.1 - 1.9e-36 125.0 8.1 2.2e-36 124.7 5.6 1.0 1 0 0 1 1 1 1 Snf7 DUF2520 PF10728.4 EXF80981.1 - 0.0018 17.7 0.1 0.0038 16.6 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF2520) ATE_C PF04377.10 EXF80982.1 - 5.5e-43 146.0 0.3 2e-42 144.2 0.1 1.9 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EXF80982.1 - 2.6e-15 55.9 0.2 6.7e-15 54.6 0.2 1.7 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus Acetyltransf_6 PF13480.1 EXF80982.1 - 0.066 13.1 1.8 0.22 11.4 0.1 2.5 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain NUDIX PF00293.23 EXF80983.1 - 2.1e-19 69.5 0.8 2.6e-19 69.1 0.6 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.1 EXF80983.1 - 0.0093 15.3 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotide hydrolase LSM PF01423.17 EXF80984.1 - 4e-13 48.7 0.0 6.6e-13 48.0 0.0 1.3 1 0 0 1 1 1 1 LSM domain Glyco_hyd_65N_2 PF14498.1 EXF80985.1 - 0.00013 21.7 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 65, N-terminal domain Glyco_hydro_65N PF03636.10 EXF80985.1 - 0.047 13.0 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Mob1_phocein PF03637.12 EXF80986.1 - 3.9e-71 238.3 0.0 4.8e-71 238.0 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family OSCP PF00213.13 EXF80987.1 - 1.9e-47 161.2 0.6 2.5e-47 160.9 0.4 1.2 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Acyl-CoA_dh_1 PF00441.19 EXF80987.1 - 0.15 12.1 2.6 3.8 7.5 0.1 2.2 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain Glyco_hydro_63 PF03200.11 EXF80988.1 - 5.4e-07 27.8 4.8 1e-05 23.6 0.1 3.5 3 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase RasGEF PF00617.14 EXF80989.1 - 6.7e-48 162.9 0.1 1.1e-47 162.2 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain Miro PF08477.8 EXF80989.1 - 4e-16 59.5 0.0 2.8e-15 56.8 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein RasGEF_N PF00618.15 EXF80989.1 - 2.7e-13 49.8 0.0 6.2e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif Ras PF00071.17 EXF80989.1 - 1.1e-07 31.3 1.2 3.2e-05 23.3 0.0 2.8 3 0 0 3 3 3 2 Ras family FtsK_SpoIIIE PF01580.13 EXF80989.1 - 0.00048 19.6 0.0 0.016 14.7 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family GTP_EFTU PF00009.22 EXF80989.1 - 0.0018 17.7 0.0 0.09 12.2 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EXF80989.1 - 0.0034 17.5 0.2 0.33 11.1 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EXF80989.1 - 0.011 15.7 0.3 0.056 13.4 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain DUF258 PF03193.11 EXF80989.1 - 0.058 12.5 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ATP_bind_1 PF03029.12 EXF80989.1 - 0.066 12.7 0.1 8.1 5.9 0.0 2.4 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EXF80989.1 - 0.078 13.8 2.7 0.24 12.1 0.0 3.2 4 0 0 4 4 3 0 AAA domain MMR_HSR1 PF01926.18 EXF80989.1 - 0.086 12.7 0.3 0.59 10.1 0.2 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase IIGP PF05049.8 EXF80989.1 - 0.1 11.4 0.1 0.1 11.4 0.1 1.6 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) ABC_tran PF00005.22 EXF80989.1 - 0.14 12.4 0.0 0.45 10.8 0.0 1.9 1 0 0 1 1 1 0 ABC transporter DUF1175 PF06672.6 EXF80991.1 - 0.076 12.3 0.1 0.39 10.0 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1175) zf-HIT PF04438.11 EXF80992.1 - 5.4e-09 35.5 10.3 7.4e-09 35.0 7.1 1.2 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 EXF80992.1 - 0.0084 15.9 7.7 0.013 15.3 5.3 1.3 1 0 0 1 1 1 1 MYND finger zf-B_box PF00643.19 EXF80992.1 - 0.29 11.0 8.2 0.43 10.5 5.7 1.2 1 0 0 1 1 1 0 B-box zinc finger PBP1_TM PF14812.1 EXF80992.1 - 1.9 8.8 5.6 0.83 10.0 1.5 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sigma70_ner PF04546.8 EXF80992.1 - 2.8 7.4 15.4 9.1 5.8 0.3 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region Nfu_N PF08712.6 EXF80993.1 - 1e-28 98.7 0.0 3.8e-28 96.9 0.0 2.0 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EXF80993.1 - 1.7e-21 75.7 0.1 2.7e-21 75.1 0.0 1.3 1 0 0 1 1 1 1 NifU-like domain PSP1 PF04468.7 EXF80994.1 - 2.7e-30 104.2 0.5 2.7e-30 104.2 0.4 2.2 2 0 0 2 2 2 1 PSP1 C-terminal conserved region HOOK PF05622.7 EXF80994.1 - 0.22 9.3 13.9 0.003 15.4 4.6 1.4 2 0 0 2 2 2 0 HOOK protein Rotavirus_VP3 PF06929.6 EXF80994.1 - 0.34 8.7 0.4 0.5 8.1 0.3 1.1 1 0 0 1 1 1 0 Rotavirus VP3 protein Spt20 PF12090.3 EXF80994.1 - 0.88 8.8 7.1 1.6 8.0 3.3 2.3 2 0 0 2 2 2 0 Spt20 family Ribosomal_L15e PF00827.12 EXF80995.1 - 4.8e-90 300.2 12.0 5.4e-90 300.0 8.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 Codanin-1_C PF15296.1 EXF80995.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.5 1 1 0 1 1 1 0 Codanin-1 C-terminus VHS PF00790.14 EXF80997.1 - 0.00062 19.4 0.0 0.0017 17.9 0.0 1.7 2 0 0 2 2 2 1 VHS domain CTD_bind PF04818.8 EXF80997.1 - 0.0019 18.4 0.0 0.0046 17.1 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. zf-C2H2_4 PF13894.1 EXF80997.1 - 0.019 15.2 3.1 5.5 7.5 0.1 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger CFIA_Pcf11 PF11526.3 EXF80997.1 - 0.084 13.0 2.0 0.97 9.6 1.4 2.3 1 1 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 RRN7 PF11781.3 EXF80997.1 - 0.11 12.0 2.1 0.3 10.6 0.4 2.1 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-H2C2_2 PF13465.1 EXF80997.1 - 0.23 11.8 0.8 17 5.9 0.0 2.7 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2HC_2 PF13913.1 EXF80997.1 - 0.4 10.3 6.5 2.7 7.7 0.7 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Glyco_transf_90 PF05686.7 EXF80998.1 - 4.8e-22 78.2 0.0 2.5e-17 62.6 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 90 Glyco_hydro_72 PF03198.9 EXF80999.1 - 2e-124 414.6 4.4 2.5e-124 414.3 3.1 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EXF80999.1 - 1.3e-05 24.5 1.2 0.00017 20.9 0.8 2.2 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FCH PF00611.18 EXF81000.1 - 5.4e-24 84.1 0.6 2e-23 82.3 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 EXF81000.1 - 2.5e-18 65.3 0.3 1.7e-12 46.6 0.0 2.6 2 0 0 2 2 2 2 Variant SH3 domain C1_1 PF00130.17 EXF81000.1 - 9.2e-15 54.1 5.3 1.4e-14 53.5 3.7 1.3 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SH3_1 PF00018.23 EXF81000.1 - 1.8e-13 49.6 0.1 3.4e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EXF81000.1 - 0.0019 17.6 0.0 0.18 11.3 0.0 2.5 2 0 0 2 2 2 1 Variant SH3 domain SH3_3 PF08239.6 EXF81000.1 - 0.0027 17.8 0.4 0.15 12.2 0.1 2.5 2 0 0 2 2 2 1 Bacterial SH3 domain Allexi_40kDa PF05549.6 EXF81000.1 - 0.043 13.1 3.7 0.072 12.3 0.1 2.5 2 1 0 2 2 2 0 Allexivirus 40kDa protein DEAD PF00270.24 EXF81001.1 - 1.3e-32 112.6 0.0 9.3e-32 109.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF81001.1 - 2.6e-22 78.4 0.0 5e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EXF81001.1 - 0.0024 17.5 0.1 0.45 10.2 0.0 2.7 2 1 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EXF81001.1 - 0.0041 16.7 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EXF81001.1 - 0.0084 16.2 0.3 0.15 12.1 0.1 2.6 2 1 0 2 2 2 1 AAA domain Helicase_C_2 PF13307.1 EXF81001.1 - 0.023 14.6 0.0 0.078 12.9 0.0 1.8 2 0 0 2 2 2 0 Helicase C-terminal domain CFEM PF05730.6 EXF81002.1 - 0.034 13.9 3.7 0.065 13.0 2.6 1.4 1 0 0 1 1 1 0 CFEM domain MFS_1 PF07690.11 EXF81003.1 - 3.9e-06 25.8 15.9 0.0013 17.4 9.3 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EXF81003.1 - 0.032 12.6 11.3 0.65 8.3 0.0 3.5 4 0 0 4 4 4 0 MFS/sugar transport protein ECH PF00378.15 EXF81005.1 - 1.1e-40 139.3 0.0 2.6e-40 138.0 0.0 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EXF81005.1 - 0.022 14.9 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region Tbf5 PF06331.7 EXF81006.1 - 5.9e-28 96.4 0.6 6.4e-28 96.3 0.4 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 UPF0254 PF06787.6 EXF81007.1 - 0.13 11.7 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) Glyco_hydro_61 PF03443.9 EXF81009.1 - 2.7e-77 259.4 0.1 3.2e-77 259.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 S4 PF01479.20 EXF81010.1 - 1.4e-11 43.5 0.0 3.7e-11 42.2 0.0 1.7 2 0 0 2 2 2 1 S4 domain Ribosomal_S4 PF00163.14 EXF81010.1 - 1.3e-10 41.4 1.3 2.3e-10 40.7 0.5 1.6 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Ribosomal_S18 PF01084.15 EXF81011.1 - 6.7e-11 41.8 0.1 1.4e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S18 DUF4145 PF13643.1 EXF81011.1 - 0.44 10.4 2.3 2.8 7.8 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4145) PPR_2 PF13041.1 EXF81012.1 - 2.7e-05 24.0 0.0 3.8 7.5 0.0 4.5 4 0 0 4 4 4 3 PPR repeat family PPR PF01535.15 EXF81012.1 - 0.00036 20.3 0.1 1.2 9.2 0.0 4.0 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.1 EXF81012.1 - 0.0038 17.3 0.0 0.069 13.4 0.0 3.1 2 0 0 2 2 2 1 Pentatricopeptide repeat domain ADH_zinc_N PF00107.21 EXF81013.1 - 6e-07 29.0 0.1 1.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF81013.1 - 0.00096 18.8 0.0 0.0016 18.2 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain zf-C2H2 PF00096.21 EXF81014.1 - 1.2e-07 31.5 13.3 6.5e-05 23.0 1.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.13 EXF81014.1 - 5.1e-05 23.0 11.3 5.1e-05 23.0 7.9 2.4 3 0 0 3 3 3 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 EXF81014.1 - 0.0016 18.6 20.4 0.0017 18.5 0.9 4.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EXF81014.1 - 0.005 17.0 1.4 0.005 17.0 1.0 3.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EXF81014.1 - 0.039 14.1 5.5 0.25 11.5 0.7 2.7 1 1 1 2 2 2 0 Zinc-finger double-stranded RNA-binding NTS_2 PF15448.1 EXF81014.1 - 0.097 12.9 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 N-terminal segments of P. falciparum erythrocyte membrane protein zf-met PF12874.2 EXF81014.1 - 0.22 11.7 3.7 7.8 6.8 0.3 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EXF81014.1 - 3 7.8 6.0 6.9 6.7 0.7 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger adh_short PF00106.20 EXF81015.1 - 3.2e-29 101.9 0.6 4.4e-29 101.5 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF81015.1 - 1.2e-26 93.9 0.0 1.6e-26 93.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF81015.1 - 1.2e-11 44.5 0.3 1.7e-11 44.0 0.2 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF81015.1 - 0.023 14.1 0.2 0.074 12.4 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Zn_clus PF00172.13 EXF81016.1 - 2.6e-07 30.4 8.6 2.6e-07 30.4 5.9 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cyclin PF08613.6 EXF81017.1 - 2e-14 54.2 0.0 4.9e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EXF81017.1 - 0.083 12.4 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 Cyclin, N-terminal domain JmjC PF02373.17 EXF81018.1 - 3.6e-36 123.8 0.5 9.9e-36 122.4 0.3 1.8 1 0 0 1 1 1 1 JmjC domain, hydroxylase zf-HC5HC2H_2 PF13832.1 EXF81018.1 - 1e-21 76.9 5.2 1.8e-21 76.2 3.6 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EXF81018.1 - 1.2e-21 76.6 5.3 1.2e-21 76.6 3.7 2.3 2 0 0 2 2 2 1 PHD-like zinc-binding domain JmjN PF02375.12 EXF81018.1 - 2.9e-14 52.3 0.2 6.6e-14 51.1 0.2 1.7 1 0 0 1 1 1 1 jmjN domain Nucleoplasmin PF03066.10 EXF81018.1 - 2.7 7.5 12.6 12 5.3 4.5 2.4 2 0 0 2 2 2 0 Nucleoplasmin PAP2 PF01569.16 EXF81019.1 - 5.2e-19 68.1 4.0 1.7e-18 66.5 2.8 2.0 1 0 0 1 1 1 1 PAP2 superfamily adh_short PF00106.20 EXF81020.1 - 2.6e-27 95.7 3.4 1.8e-26 93.0 2.4 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF81020.1 - 1.9e-21 76.9 0.0 2.3e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF81020.1 - 3.9e-11 42.9 0.4 6.7e-11 42.1 0.3 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF81020.1 - 1.4e-05 24.6 0.6 0.00015 21.2 0.1 2.6 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF81020.1 - 3e-05 24.0 0.5 0.00018 21.5 0.3 2.1 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EXF81020.1 - 0.0047 15.8 0.0 0.052 12.4 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EXF81020.1 - 0.014 15.5 0.0 0.048 13.7 0.0 1.8 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EXF81020.1 - 0.041 13.5 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EXF81020.1 - 0.069 13.5 0.0 0.17 12.3 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 EXF81021.1 - 2.7e-41 140.5 0.6 1.7e-40 138.0 0.1 2.3 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 EXF81021.1 - 7.6e-30 102.2 1.5 2.6e-29 100.5 0.1 2.3 2 0 0 2 2 2 1 Repeat in ubiquitin-activating (UBA) protein UAE_UbL PF14732.1 EXF81021.1 - 1.1e-22 79.8 1.7 6.8e-22 77.3 0.3 2.3 2 0 0 2 2 2 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.4 EXF81021.1 - 2.6e-19 68.3 0.9 2.6e-19 68.3 0.6 2.3 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.1 EXF81021.1 - 0.00073 19.7 0.1 0.0022 18.2 0.1 1.8 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EXF81021.1 - 0.011 15.7 0.0 0.033 14.3 0.0 1.8 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EXF81021.1 - 0.087 13.2 0.2 2.9 8.3 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pex14_N PF04695.8 EXF81021.1 - 3.9 7.5 15.7 0.18 11.8 6.5 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2419 PF10343.4 EXF81022.1 - 2.2e-132 440.6 0.0 2.6e-132 440.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) DUF1563 PF07599.6 EXF81022.1 - 0.033 14.0 0.1 0.069 13.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1563) DNA_pol_delta_4 PF04081.8 EXF81023.1 - 2e-30 105.5 0.7 2.9e-30 105.0 0.5 1.3 1 0 0 1 1 1 1 DNA polymerase delta, subunit 4 DUF2031 PF09592.5 EXF81023.1 - 0.14 11.2 0.9 0.26 10.4 0.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) WD40 PF00400.27 EXF81024.1 - 2.9e-22 77.6 13.2 6.6e-11 41.6 0.2 7.1 7 0 0 7 7 7 3 WD domain, G-beta repeat Ank PF00023.25 EXF81024.1 - 6.8e-20 69.8 0.3 0.00028 20.5 0.0 5.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EXF81024.1 - 3.7e-17 62.3 0.1 2.7e-07 30.8 0.0 4.6 3 2 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EXF81024.1 - 1.8e-16 60.2 0.0 1.5e-08 34.8 0.0 4.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EXF81024.1 - 8.5e-14 50.3 0.9 0.026 14.7 0.0 6.1 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EXF81024.1 - 6.6e-11 42.0 0.3 2.2e-07 30.9 0.1 4.8 5 0 0 5 5 5 1 Ankyrin repeats (many copies) eIF2A PF08662.6 EXF81024.1 - 0.0033 17.1 0.2 0.013 15.1 0.0 2.1 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nbas_N PF15492.1 EXF81024.1 - 0.016 14.3 0.1 1.1 8.3 0.0 2.8 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Coatomer_WDAD PF04053.9 EXF81024.1 - 0.051 12.3 0.0 0.064 12.0 0.0 1.1 1 0 0 1 1 1 0 Coatomer WD associated region Lactonase PF10282.4 EXF81024.1 - 0.11 11.5 0.0 0.98 8.4 0.0 1.9 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller Ribosomal_L32p PF01783.18 EXF81025.1 - 1.3e-13 50.8 7.1 1.8e-13 50.4 4.9 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family DUF4428 PF14471.1 EXF81025.1 - 0.061 13.0 1.5 0.099 12.4 0.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4428) PolC_DP2 PF03833.8 EXF81025.1 - 0.15 9.6 0.2 0.17 9.5 0.1 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-ribbon_3 PF13248.1 EXF81025.1 - 0.62 9.3 6.5 1.1 8.5 4.5 1.4 1 0 0 1 1 1 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EXF81025.1 - 3.3 7.7 6.9 3.7 7.5 0.8 2.3 1 1 1 2 2 2 0 Zinc ribbon domain DUF35_N PF12172.3 EXF81025.1 - 4.2 7.4 6.5 12 5.9 4.5 1.7 1 1 0 1 1 1 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Septin PF00735.13 EXF81026.1 - 2.4e-112 374.5 0.7 2.8e-112 374.3 0.5 1.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EXF81026.1 - 1.6e-06 28.0 0.0 2.9e-06 27.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EXF81026.1 - 4e-06 26.0 0.0 7.1e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.22 EXF81026.1 - 8.4e-06 25.3 0.1 0.0013 18.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EXF81026.1 - 4.7e-05 22.6 0.0 9.2e-05 21.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EXF81026.1 - 0.00089 19.1 0.3 1.2 8.9 0.1 2.6 1 1 1 2 2 2 2 Dynamin family AAA_10 PF12846.2 EXF81026.1 - 0.0037 16.7 0.1 0.0068 15.8 0.0 1.4 1 1 0 1 1 1 1 AAA-like domain Gtr1_RagA PF04670.7 EXF81026.1 - 0.006 15.7 0.0 0.077 12.1 0.0 2.2 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region AAA_23 PF13476.1 EXF81026.1 - 0.0064 16.8 0.0 0.012 15.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EXF81026.1 - 0.0073 16.4 0.0 0.018 15.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EXF81026.1 - 0.0085 16.3 0.2 0.015 15.5 0.1 1.7 1 1 0 1 1 1 1 ABC transporter NB-ARC PF00931.17 EXF81026.1 - 0.016 14.0 0.1 0.025 13.4 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain T2SE PF00437.15 EXF81026.1 - 0.03 13.2 0.0 0.061 12.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 EXF81026.1 - 0.042 13.8 0.1 0.067 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EXF81026.1 - 0.043 13.2 0.0 0.083 12.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF1542 PF07564.6 EXF81026.1 - 0.15 12.1 0.2 0.3 11.1 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1542) AAA_29 PF13555.1 EXF81026.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Guanylate_kin PF00625.16 EXF81027.1 - 1.8e-63 213.2 0.0 2.2e-63 212.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 EXF81027.1 - 3.2e-06 27.4 0.0 1.5e-05 25.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EXF81027.1 - 1.3e-05 25.1 0.0 5.3e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EXF81027.1 - 0.00013 21.9 0.0 0.0002 21.3 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EXF81027.1 - 0.00049 20.9 0.1 0.00079 20.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EXF81027.1 - 0.00076 19.6 0.0 0.0036 17.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EXF81027.1 - 0.0033 16.6 0.0 0.0063 15.7 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 EXF81027.1 - 0.033 14.0 0.0 0.11 12.3 0.0 2.1 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EXF81027.1 - 0.035 13.8 0.2 1.9 8.1 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase AAA_28 PF13521.1 EXF81027.1 - 0.036 14.0 0.0 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EXF81027.1 - 0.081 13.2 0.1 0.12 12.6 0.0 1.7 1 1 0 1 1 1 0 ABC transporter DUF1895 PF08988.5 EXF81027.1 - 0.095 12.7 0.4 0.16 12.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1895) Glyco_hydro_72 PF03198.9 EXF81028.1 - 4.3e-120 400.4 0.3 5.2e-120 400.1 0.2 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EXF81028.1 - 0.00019 20.7 0.0 0.00096 18.4 0.0 1.9 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ATP-grasp_2 PF08442.5 EXF81029.1 - 1.9e-08 33.9 0.0 2.9e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain Citrate_synt PF00285.16 EXF81030.1 - 1.3e-19 70.1 0.0 6.1e-17 61.3 0.0 2.9 1 1 1 2 2 2 2 Citrate synthase CoA_binding PF02629.14 EXF81030.1 - 2.2e-18 66.5 0.1 1.3e-17 64.1 0.0 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EXF81030.1 - 3.1e-14 52.8 0.1 5.3e-14 52.0 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.1 EXF81030.1 - 1.2e-05 24.9 0.0 0.00023 20.7 0.0 2.3 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain Ribosomal_L30 PF00327.15 EXF81031.1 - 2.6e-17 62.1 0.0 3.3e-17 61.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e MRG PF05712.8 EXF81032.1 - 1.6e-56 190.3 0.1 2.2e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 MRG MRI PF15325.1 EXF81032.1 - 0.14 13.1 0.6 0.31 12.0 0.4 1.5 1 0 0 1 1 1 0 Modulator of retrovirus infection Cnl2_NKP2 PF09447.5 EXF81033.1 - 1.7e-24 85.2 2.8 7.1e-24 83.2 0.5 2.2 2 0 0 2 2 2 1 Cnl2/NKP2 family protein TMF_DNA_bd PF12329.3 EXF81033.1 - 0.0044 16.7 0.3 0.0044 16.7 0.2 2.6 2 1 1 3 3 3 1 TATA element modulatory factor 1 DNA binding DUF2365 PF10157.4 EXF81033.1 - 0.005 16.7 0.3 0.012 15.5 0.1 1.7 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2365) DUF2968 PF11180.3 EXF81033.1 - 0.0082 15.5 9.4 0.12 11.7 3.1 2.0 1 1 0 2 2 2 2 Protein of unknown function (DUF2968) Syntaxin_2 PF14523.1 EXF81033.1 - 0.0089 16.0 1.2 1.5 8.9 0.7 2.2 2 0 0 2 2 2 1 Syntaxin-like protein Prefoldin_2 PF01920.15 EXF81033.1 - 0.03 14.0 0.2 0.03 14.0 0.1 2.3 2 1 0 2 2 2 0 Prefoldin subunit Viral_P18 PF04521.8 EXF81033.1 - 0.031 13.7 0.5 2.3 7.6 0.0 2.2 2 0 0 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein DUF972 PF06156.8 EXF81033.1 - 0.047 14.0 3.6 3.2 8.1 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) FlgN PF05130.7 EXF81033.1 - 0.057 13.6 2.4 1.3 9.2 0.4 2.2 2 0 0 2 2 2 0 FlgN protein YlqD PF11068.3 EXF81033.1 - 0.082 12.9 3.5 0.29 11.1 0.0 2.2 2 0 0 2 2 2 0 YlqD protein V_ATPase_I PF01496.14 EXF81033.1 - 0.084 10.7 1.2 0.1 10.4 0.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spc24 PF08286.6 EXF81033.1 - 0.12 12.0 3.2 0.64 9.7 0.1 2.3 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 TMCO5 PF14992.1 EXF81033.1 - 0.17 10.9 6.3 0.83 8.7 0.2 2.1 1 1 1 2 2 2 0 TMCO5 family DivIC PF04977.10 EXF81033.1 - 0.26 10.7 0.1 0.26 10.7 0.1 2.4 2 1 0 2 2 2 0 Septum formation initiator Prominin PF05478.6 EXF81033.1 - 0.36 8.3 4.2 1.3 6.4 0.2 2.0 1 1 1 2 2 2 0 Prominin HSCB_C PF07743.8 EXF81033.1 - 0.53 10.7 4.9 2.9 8.4 0.0 2.8 2 1 0 2 2 2 0 HSCB C-terminal oligomerisation domain DUF724 PF05266.9 EXF81033.1 - 0.59 9.7 4.2 1.8 8.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) PspA_IM30 PF04012.7 EXF81033.1 - 0.65 9.3 12.1 4.8 6.4 8.4 2.0 1 1 0 1 1 1 0 PspA/IM30 family TMPIT PF07851.8 EXF81033.1 - 1.9 7.5 3.9 0.96 8.4 1.1 1.6 1 1 1 2 2 2 0 TMPIT-like protein DUF1192 PF06698.6 EXF81033.1 - 3.3 7.5 9.6 0.56 10.0 0.4 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1192) M PF02370.11 EXF81033.1 - 5.3 7.7 8.0 0.59 10.6 1.2 2.7 3 0 0 3 3 2 0 M protein repeat CENP-Q PF13094.1 EXF81035.1 - 5.4e-29 101.2 0.1 5.4e-29 101.2 0.1 4.4 2 1 0 4 4 4 1 CENP-Q, a CENPA-CAD centromere complex subunit Methyltransf_11 PF08241.7 EXF81039.1 - 8.8e-07 29.3 0.0 0.00012 22.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF81039.1 - 0.00018 21.2 0.0 0.00034 20.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF81039.1 - 0.0024 18.4 0.0 0.0043 17.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF81039.1 - 0.0032 17.7 0.1 0.051 13.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF81039.1 - 0.0036 17.7 0.0 0.016 15.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF81039.1 - 0.023 14.3 0.0 0.64 9.5 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Myb_DNA-binding PF00249.26 EXF81040.1 - 1.3e-11 44.3 2.6 3.3e-09 36.6 0.0 2.8 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EXF81040.1 - 2.7e-07 30.5 4.9 8e-05 22.6 0.1 2.7 3 0 0 3 3 3 2 Myb-like DNA-binding domain CAP_GLY PF01302.20 EXF81041.1 - 7.2e-24 83.2 1.6 1.1e-23 82.7 1.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ubiquitin_2 PF14560.1 EXF81041.1 - 3.6e-22 78.4 0.0 6.7e-22 77.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain ubiquitin PF00240.18 EXF81041.1 - 0.00015 21.0 0.0 0.00036 19.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family CAS_CSE1 PF03378.10 EXF81042.1 - 1.1e-160 534.7 3.4 1.8e-159 530.7 0.4 2.6 3 0 0 3 3 3 2 CAS/CSE protein, C-terminus Cse1 PF08506.5 EXF81042.1 - 2.4e-154 513.3 3.3 2.4e-154 513.3 2.3 1.6 2 0 0 2 2 2 1 Cse1 IBN_N PF03810.14 EXF81042.1 - 1.8e-14 53.3 0.6 1e-13 50.9 0.1 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EXF81042.1 - 0.35 10.7 5.2 3 7.7 0.4 4.1 3 3 0 3 3 3 0 Exportin 1-like protein DUF3384 PF11864.3 EXF81043.1 - 1.1e-85 287.8 0.0 2.3e-85 286.8 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 EXF81043.1 - 5.4e-54 182.4 0.0 9.9e-54 181.5 0.0 1.5 1 0 0 1 1 1 1 Rap/ran-GAP Tuberin PF03542.11 EXF81043.1 - 3.4e-31 108.6 5.6 1.1e-28 100.2 1.6 2.4 2 0 0 2 2 2 2 Tuberin DcuC PF03606.10 EXF81043.1 - 0.16 10.2 0.0 0.28 9.3 0.0 1.3 1 0 0 1 1 1 0 C4-dicarboxylate anaerobic carrier Acetyltransf_1 PF00583.19 EXF81044.1 - 2.2e-08 34.0 0.0 1.6e-06 28.0 0.0 2.7 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EXF81044.1 - 7.8e-06 26.0 0.3 4.6e-05 23.5 0.0 2.4 4 0 0 4 4 4 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EXF81044.1 - 0.001 19.2 0.0 0.0023 18.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CENP-I PF07778.6 EXF81045.1 - 7.7e-99 331.2 1.4 6.9e-96 321.4 0.0 2.2 1 1 1 2 2 2 2 Mis6 ABC_tran PF00005.22 EXF81046.1 - 5.5e-16 59.1 0.1 5.4e-15 55.8 0.1 2.1 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EXF81046.1 - 2e-10 41.1 0.4 0.00039 20.4 0.3 2.2 1 1 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EXF81046.1 - 0.00031 19.9 0.0 0.1 11.6 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EXF81046.1 - 0.00067 19.1 0.2 0.0015 18.0 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3584 PF12128.3 EXF81046.1 - 0.0013 16.1 0.2 0.0017 15.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) SMC_N PF02463.14 EXF81046.1 - 0.0019 17.4 0.1 1.7 7.8 0.0 2.1 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EXF81046.1 - 0.006 16.5 0.7 0.012 15.6 0.5 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EXF81046.1 - 0.0064 17.2 1.2 0.023 15.5 0.8 2.0 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EXF81046.1 - 0.0078 16.5 0.0 0.012 15.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EXF81046.1 - 0.0087 15.5 0.1 0.013 14.9 0.1 1.2 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.1 EXF81046.1 - 0.012 14.9 1.0 0.06 12.7 0.7 2.1 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EXF81046.1 - 0.017 15.0 0.5 0.033 14.1 0.3 1.4 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EXF81046.1 - 0.019 14.1 0.1 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EXF81046.1 - 0.029 14.5 0.9 0.18 11.9 0.7 2.1 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.17 EXF81046.1 - 0.033 13.6 0.1 0.05 13.0 0.1 1.4 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain Arf PF00025.16 EXF81046.1 - 0.057 12.6 0.2 0.12 11.5 0.2 1.7 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_14 PF13173.1 EXF81046.1 - 0.06 13.2 0.1 0.28 11.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EXF81046.1 - 0.062 12.7 0.0 0.074 12.4 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA PF00004.24 EXF81046.1 - 0.093 12.9 0.5 0.32 11.2 0.4 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EXF81046.1 - 0.11 11.3 0.1 0.16 10.8 0.1 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EXF81046.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NACHT PF05729.7 EXF81046.1 - 0.12 11.9 0.1 0.21 11.2 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA_13 PF13166.1 EXF81046.1 - 0.13 10.6 0.1 0.17 10.2 0.0 1.1 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EXF81046.1 - 0.2 11.0 0.3 0.3 10.5 0.2 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DNA_pol_E_B PF04042.11 EXF81047.1 - 2.7e-40 137.8 0.5 1.5e-37 128.9 0.3 2.2 1 1 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF4334 PF14232.1 EXF81047.1 - 0.22 11.2 1.0 0.61 9.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4334) PALP PF00291.20 EXF81049.1 - 7.6e-63 212.5 1.9 8.6e-63 212.3 1.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Aminotran_1_2 PF00155.16 EXF81049.1 - 0.034 13.1 0.0 0.092 11.6 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class I and II tRNA-synt_1g PF09334.6 EXF81050.1 - 3.4e-120 401.2 0.1 5.1e-120 400.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (M) Acetyltransf_3 PF13302.1 EXF81050.1 - 9.7e-24 84.1 0.1 3.2e-23 82.4 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain tRNA-synt_1 PF00133.17 EXF81050.1 - 9.1e-23 80.0 5.8 1.1e-09 36.8 0.1 3.9 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EXF81050.1 - 3.5e-09 36.2 0.1 0.00023 20.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Acetyltransf_1 PF00583.19 EXF81050.1 - 5.9e-07 29.4 0.8 5.1e-06 26.4 0.6 2.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EXF81050.1 - 1.9e-06 27.8 2.3 0.00039 20.3 1.4 2.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EXF81050.1 - 0.00028 20.6 0.3 0.46 10.2 0.0 2.6 1 1 1 2 2 2 2 FR47-like protein ESCRT-II PF05871.7 EXF81050.1 - 0.013 15.4 0.1 0.028 14.3 0.0 1.6 1 0 0 1 1 1 0 ESCRT-II complex subunit Peripla_BP_3 PF13377.1 EXF81050.1 - 0.04 13.9 0.3 8.5 6.3 0.0 3.7 3 1 1 4 4 4 0 Periplasmic binding protein-like domain DUF2761 PF10959.3 EXF81050.1 - 0.061 12.9 0.0 1.2 8.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2761) Hira PF07569.6 EXF81050.1 - 0.14 11.3 0.1 0.25 10.5 0.1 1.3 1 0 0 1 1 1 0 TUP1-like enhancer of split NTF2 PF02136.15 EXF81051.1 - 0.0081 16.5 0.0 0.024 15.0 0.0 1.7 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain PPTA PF01239.17 EXF81052.1 - 1.3e-41 138.2 15.2 2e-08 33.2 0.0 5.5 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat TPR_16 PF13432.1 EXF81052.1 - 0.0038 17.8 0.4 0.018 15.7 0.3 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EXF81052.1 - 0.0045 17.5 1.1 0.048 14.3 0.3 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EXF81052.1 - 0.029 14.7 2.8 0.37 11.1 1.9 2.7 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EXF81052.1 - 0.056 13.3 1.1 0.23 11.4 0.8 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat GHMP_kinases_N PF00288.21 EXF81054.1 - 5.1e-21 74.5 0.0 1.7e-20 72.8 0.0 1.9 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EXF81054.1 - 6.6e-09 35.8 0.0 1.6e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal GalKase_gal_bdg PF10509.4 EXF81054.1 - 0.007 15.6 0.0 0.017 14.3 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature ABM PF03992.11 EXF81055.1 - 1.3e-09 37.9 4.5 0.00069 19.6 0.0 3.1 2 1 0 2 2 2 2 Antibiotic biosynthesis monooxygenase Dehydratase_hem PF13816.1 EXF81055.1 - 0.0026 16.8 0.7 1.1 8.2 0.0 2.1 2 0 0 2 2 2 2 Haem-containing dehydratase Ribosomal_L38e PF01781.13 EXF81056.1 - 4.9e-33 112.6 2.7 5.7e-33 112.4 1.9 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family LAGLIDADG_WhiA PF14527.1 EXF81056.1 - 0.037 13.8 0.1 0.045 13.6 0.0 1.1 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain Podovirus_Gp16 PF05894.7 EXF81056.1 - 0.073 12.3 0.0 0.079 12.2 0.0 1.1 1 0 0 1 1 1 0 Podovirus DNA encapsidation protein (Gp16) Ish1 PF10281.4 EXF81057.1 - 0.0016 18.4 0.0 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 Putative stress-responsive nuclear envelope protein Peptidase_M48 PF01435.13 EXF81058.1 - 4.1e-50 170.4 0.2 6e-50 169.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 EXF81058.1 - 0.026 13.5 0.1 0.052 12.5 0.0 1.5 1 0 0 1 1 1 0 BlaR1 peptidase M56 DUF2201_N PF13203.1 EXF81058.1 - 0.044 12.9 0.3 0.093 11.8 0.2 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF955 PF06114.8 EXF81058.1 - 0.14 11.8 0.5 1 9.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF955) Ribosomal_L34 PF00468.12 EXF81059.1 - 5.4e-13 48.3 11.7 1e-12 47.4 8.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L34 Glyco_hydro_3 PF00933.16 EXF81061.1 - 1.6e-91 306.4 0.0 2.2e-91 305.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF81061.1 - 4.1e-49 167.1 0.2 3.6e-48 164.0 0.1 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF81061.1 - 2.1e-23 82.0 0.1 4.3e-23 81.0 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain CARDB PF07705.6 EXF81061.1 - 0.023 14.7 0.2 0.077 13.0 0.0 2.0 2 0 0 2 2 2 0 CARDB PYC_OADA PF02436.13 EXF81061.1 - 0.16 11.4 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Conserved carboxylase domain Lipase_3 PF01764.20 EXF81062.1 - 1.6e-37 128.2 0.0 2.6e-37 127.5 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_8 PF06259.7 EXF81062.1 - 0.0035 16.8 0.0 0.0072 15.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase Cutinase PF01083.17 EXF81062.1 - 0.0084 15.8 0.5 0.0084 15.8 0.4 2.4 2 1 0 2 2 2 1 Cutinase Abhydrolase_6 PF12697.2 EXF81062.1 - 0.02 14.7 0.0 0.028 14.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF81062.1 - 0.038 13.7 0.0 0.059 13.1 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family SNF2_N PF00176.18 EXF81063.1 - 4.1e-62 209.6 0.0 7.5e-62 208.8 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EXF81063.1 - 3.2e-13 49.3 0.0 2.4e-12 46.5 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EXF81063.1 - 8.1e-07 28.6 5.5 8.1e-07 28.6 3.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) AAA_34 PF13872.1 EXF81063.1 - 5.9e-05 21.9 0.0 0.00022 20.1 0.0 1.9 2 0 0 2 2 2 1 P-loop containing NTP hydrolase pore-1 zf-C3HC4_3 PF13920.1 EXF81063.1 - 0.00053 19.6 6.9 0.00053 19.6 4.8 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EXF81063.1 - 0.0011 18.9 6.4 0.0011 18.9 4.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EXF81063.1 - 0.0029 17.3 7.5 0.0029 17.3 5.2 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EXF81063.1 - 0.0055 16.3 6.7 0.0055 16.3 4.7 2.2 2 0 0 2 2 2 1 zinc-RING finger domain DUF4011 PF13195.1 EXF81063.1 - 0.49 10.3 9.1 0.042 13.8 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4011) AT_hook PF02178.14 EXF81063.1 - 2 8.3 27.8 0.72 9.7 3.9 5.0 4 0 0 4 4 4 0 AT hook motif LRR_6 PF13516.1 EXF81064.1 - 0.002 18.0 0.7 3.9 7.8 0.0 5.8 7 0 0 7 7 7 1 Leucine Rich repeat LRR_8 PF13855.1 EXF81064.1 - 0.087 12.5 1.0 16 5.3 0.1 3.6 3 1 0 3 3 3 0 Leucine rich repeat DDE_3 PF13358.1 EXF81064.1 - 0.1 12.3 0.5 0.93 9.2 0.0 2.4 2 0 0 2 2 2 0 DDE superfamily endonuclease zf-DHHC PF01529.15 EXF81065.1 - 2.8e-42 144.0 5.8 4.4e-42 143.4 4.0 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase DZR PF12773.2 EXF81065.1 - 0.093 12.5 6.3 0.18 11.6 4.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon Ssl1 PF04056.9 EXF81066.1 - 6.4e-74 247.7 0.0 8.8e-74 247.2 0.0 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EXF81066.1 - 7.5e-16 57.8 9.8 7.5e-16 57.8 6.8 3.0 2 2 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EXF81066.1 - 3.5e-11 43.5 0.0 6.1e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EXF81066.1 - 0.035 13.8 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain Glyoxalase PF00903.20 EXF81067.1 - 1.6e-23 83.0 0.1 2.9e-15 56.3 0.0 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EXF81067.1 - 6.7e-13 48.6 0.1 3.7e-06 26.9 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EXF81067.1 - 3.2e-11 43.7 0.0 3.6e-06 27.5 0.0 2.6 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 EXF81067.1 - 2.5e-05 24.2 0.1 0.6 9.9 0.0 3.1 2 1 0 2 2 2 2 Glyoxalase-like domain Glyoxalase_5 PF14696.1 EXF81067.1 - 0.00041 20.2 0.0 0.003 17.5 0.0 2.1 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Herpes_UL36 PF03586.8 EXF81067.1 - 0.12 11.5 0.1 1.5 7.8 0.0 2.4 3 0 0 3 3 3 0 Herpesvirus UL36 tegument protein TcdB_N PF12918.2 EXF81069.1 - 0.11 12.5 0.1 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 TcdB toxin N-terminal helical domain Ribosomal_L27e PF01777.13 EXF81070.1 - 7.3e-36 122.1 4.4 1e-35 121.6 3.0 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family DUF3788 PF12663.2 EXF81070.1 - 0.055 13.1 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3788) KOW PF00467.24 EXF81070.1 - 0.14 11.9 1.8 0.2 11.4 0.4 2.0 2 0 0 2 2 2 0 KOW motif TPT PF03151.11 EXF81071.1 - 3.1e-27 95.0 13.7 3.1e-27 95.0 9.5 2.7 3 1 0 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EXF81071.1 - 0.0022 16.9 26.0 0.025 13.5 18.0 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EXF81071.1 - 0.019 15.0 35.7 0.05 13.6 8.8 2.7 3 1 0 3 3 3 0 EamA-like transporter family NAD_binding_8 PF13450.1 EXF81072.1 - 3.4e-09 36.5 0.1 8.7e-09 35.2 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EXF81072.1 - 7.9e-05 21.9 0.0 0.00017 20.8 0.0 1.5 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox_3 PF13738.1 EXF81072.1 - 0.0043 17.1 0.9 0.0073 16.3 0.1 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF81072.1 - 0.012 15.5 0.0 0.04 13.7 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EXF81072.1 - 0.018 14.1 0.1 0.027 13.5 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EXF81072.1 - 0.035 12.5 0.1 0.055 11.9 0.1 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EXF81072.1 - 0.1 11.6 0.9 0.19 10.7 0.1 1.8 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.19 EXF81072.1 - 0.1 11.4 0.2 0.15 10.8 0.2 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.1 EXF81072.1 - 0.15 11.7 0.2 1.1 8.9 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding GIDA PF01134.17 EXF81072.1 - 0.18 10.6 0.5 2.4 6.9 0.1 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EXF81072.1 - 0.18 10.6 0.7 0.41 9.5 0.1 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein HATPase_c PF02518.21 EXF81074.1 - 3.5e-28 97.5 0.1 7.6e-28 96.4 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EXF81074.1 - 7.5e-22 77.4 0.2 1.9e-21 76.1 0.1 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EXF81074.1 - 1.9e-20 72.6 0.2 6.6e-20 70.8 0.1 2.1 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain AAA_16 PF13191.1 EXF81074.1 - 1.3e-12 48.1 0.1 8.1e-12 45.5 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain GAF_2 PF13185.1 EXF81074.1 - 2.8e-11 44.1 0.0 1.2e-10 42.0 0.0 2.1 1 0 0 1 1 1 1 GAF domain Pkinase PF00069.20 EXF81074.1 - 1.5e-09 37.4 0.0 6.4e-09 35.3 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain GAF_3 PF13492.1 EXF81074.1 - 7.8e-08 32.4 0.0 1.8e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 GAF domain HATPase_c_3 PF13589.1 EXF81074.1 - 0.0005 19.7 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AAA_22 PF13401.1 EXF81074.1 - 0.0086 16.2 0.0 0.66 10.1 0.0 3.1 2 0 0 2 2 2 1 AAA domain TPR_8 PF13181.1 EXF81074.1 - 0.0091 15.7 1.8 0.51 10.2 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EXF81074.1 - 0.04 13.8 13.0 0.93 9.4 2.5 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EXF81074.1 - 3.4 7.8 8.5 0.64 10.0 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-H2C2_2 PF13465.1 EXF81075.1 - 1e-20 72.9 26.9 5.7e-08 32.6 0.4 5.0 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2 PF00096.21 EXF81075.1 - 5e-20 70.5 31.0 1.4e-05 25.0 0.1 4.6 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF81075.1 - 1.5e-10 40.6 26.9 0.00054 20.1 1.2 4.7 4 0 0 4 4 4 3 C2H2-type zinc finger zf-TRAF PF02176.13 EXF81075.1 - 0.0063 16.8 15.0 0.026 14.9 0.8 3.3 1 1 2 3 3 3 2 TRAF-type zinc finger Ogr_Delta PF04606.7 EXF81075.1 - 0.012 15.2 1.2 2.7 7.7 0.1 2.6 1 1 1 2 2 2 0 Ogr/Delta-like zinc finger zf-met PF12874.2 EXF81075.1 - 0.024 14.8 1.0 0.024 14.8 0.7 5.0 6 0 0 6 6 6 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EXF81075.1 - 0.13 12.4 15.7 1.5 9.0 0.4 4.5 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding CHORD PF04968.7 EXF81075.1 - 1.9 8.7 16.2 4.5 7.6 0.1 4.3 1 1 3 4 4 4 0 CHORD Peptidase_M41 PF01434.13 EXF81076.1 - 6.9e-69 231.5 1.2 1.1e-68 230.9 0.9 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EXF81076.1 - 5.9e-43 146.2 0.0 1.4e-42 145.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EXF81076.1 - 2.4e-05 24.4 0.5 0.0064 16.5 0.0 3.6 2 1 2 4 4 4 1 AAA ATPase domain AAA_17 PF13207.1 EXF81076.1 - 2.7e-05 24.9 0.0 7.1e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EXF81076.1 - 2.9e-05 23.7 0.0 0.00012 21.7 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EXF81076.1 - 5.2e-05 22.1 0.0 9.2e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EXF81076.1 - 0.0004 20.2 0.0 0.0012 18.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EXF81076.1 - 0.00042 20.4 1.3 0.043 13.9 0.1 3.1 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EXF81076.1 - 0.001 18.1 0.0 0.0019 17.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EXF81076.1 - 0.004 16.5 0.1 0.012 15.0 0.1 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Zeta_toxin PF06414.7 EXF81076.1 - 0.006 15.7 0.7 0.014 14.4 0.3 1.8 1 1 1 2 2 2 1 Zeta toxin Mg_chelatase PF01078.16 EXF81076.1 - 0.0069 15.5 0.3 0.016 14.3 0.2 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EXF81076.1 - 0.0078 15.9 0.3 0.022 14.4 0.2 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_2 PF07724.9 EXF81076.1 - 0.021 14.7 0.0 0.06 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 EXF81076.1 - 0.024 14.0 0.8 0.37 10.1 0.2 2.3 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.1 EXF81076.1 - 0.029 14.2 0.0 0.068 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EXF81076.1 - 0.038 13.9 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain PROL5-SMR PF15621.1 EXF81076.1 - 4.4 7.7 13.9 4.7 7.6 8.3 1.9 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family adh_short_C2 PF13561.1 EXF81077.1 - 2.5e-29 102.7 0.5 2.9e-29 102.5 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EXF81077.1 - 1.7e-27 96.3 1.5 2.3e-27 95.9 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF81077.1 - 5e-12 45.8 0.8 1.2e-11 44.5 0.5 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF81077.1 - 6.4e-05 22.4 0.2 9.4e-05 21.9 0.2 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF3387 PF11867.3 EXF81077.1 - 0.083 11.8 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3387) Dioxygenase_C PF00775.16 EXF81078.1 - 5.5e-08 32.2 0.8 1.2e-07 31.1 0.6 1.7 1 1 0 1 1 1 1 Dioxygenase YcaO PF02624.11 EXF81078.1 - 0.014 14.9 1.0 0.023 14.1 0.7 1.4 1 0 0 1 1 1 0 YcaO-like family Abhydrolase_6 PF12697.2 EXF81079.1 - 2.3e-31 109.4 1.5 2.8e-31 109.1 1.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF81079.1 - 4.6e-12 45.9 0.1 9.7e-12 44.8 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF81079.1 - 4e-11 42.9 0.1 1.9e-10 40.7 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EXF81079.1 - 1.2e-08 34.7 0.1 2.3e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Fungal_trans_2 PF11951.3 EXF81081.1 - 0.0022 16.6 0.2 0.0055 15.3 0.1 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain TerB-N PF13208.1 EXF81081.1 - 0.013 14.9 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 TerB-N Ribonuclease_3 PF00636.21 EXF81083.1 - 1e-43 148.3 0.0 1.3e-22 80.4 0.0 3.1 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EXF81083.1 - 3.1e-25 88.5 0.0 6e-10 39.1 0.0 3.7 3 0 0 3 3 3 3 Ribonuclease-III-like Dicer_dimer PF03368.9 EXF81083.1 - 6.7e-18 64.2 0.5 7.1e-16 57.7 0.1 3.0 3 0 0 3 3 3 1 Dicer dimerisation domain Helicase_C PF00271.26 EXF81083.1 - 9.9e-17 60.5 0.0 2.3e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EXF81083.1 - 8.8e-15 55.0 0.3 3.8e-14 52.9 0.2 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EXF81083.1 - 2.4e-10 40.1 0.0 8e-10 38.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Flavi_DEAD PF07652.9 EXF81083.1 - 0.0069 16.1 0.1 0.021 14.5 0.1 1.8 1 0 0 1 1 1 1 Flavivirus DEAD domain Methyltransf_24 PF13578.1 EXF81083.1 - 0.1 13.4 0.2 24 5.8 0.0 3.7 3 0 0 3 3 3 0 Methyltransferase domain PhoH PF02562.11 EXF81083.1 - 0.1 11.8 0.0 0.24 10.6 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein TAP42 PF04177.7 EXF81084.1 - 7.8e-101 337.4 0.0 8.8e-101 337.2 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family Alliinase_C PF04864.8 EXF81085.1 - 0.027 13.1 0.2 0.044 12.4 0.1 1.2 1 0 0 1 1 1 0 Allinase Secretin PF00263.16 EXF81085.1 - 0.079 12.3 0.1 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial type II and III secretion system protein DUF1899 PF08953.6 EXF81087.1 - 0.0011 18.5 0.1 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) DUF2057 PF09829.4 EXF81087.1 - 0.1 12.2 0.0 0.11 12.1 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) CENP-B_dimeris PF09026.5 EXF81088.1 - 2.8 8.2 16.4 0.3 11.3 3.5 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Sigma70_ner PF04546.8 EXF81088.1 - 9.8 5.7 15.5 8.4 5.9 1.7 2.9 3 0 0 3 3 3 0 Sigma-70, non-essential region CPSase_L_D2 PF02786.12 EXF81089.1 - 4.8e-112 372.3 0.2 1.7e-83 279.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain GATase PF00117.23 EXF81089.1 - 4.3e-44 150.2 0.0 9.1e-44 149.2 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CPSase_sm_chain PF00988.17 EXF81089.1 - 6.2e-44 148.6 0.0 1.6e-43 147.3 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain CPSase_L_D3 PF02787.14 EXF81089.1 - 1.8e-42 144.0 0.3 5.1e-42 142.5 0.1 1.9 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain CPSase_L_chain PF00289.17 EXF81089.1 - 5.2e-42 142.4 0.0 2.5e-20 72.6 0.0 3.4 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain OTCace_N PF02729.16 EXF81089.1 - 8.1e-42 142.2 0.0 1.7e-41 141.2 0.0 1.5 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain ATP-grasp_4 PF13535.1 EXF81089.1 - 1.6e-35 122.5 0.2 4.3e-22 78.7 0.0 3.0 3 0 0 3 3 3 2 ATP-grasp domain OTCace PF00185.19 EXF81089.1 - 1.1e-34 119.6 0.0 2.8e-34 118.2 0.0 1.8 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain ATPgrasp_Ter PF15632.1 EXF81089.1 - 3e-22 78.7 0.0 1.9e-11 43.2 0.0 3.9 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon MGS PF02142.17 EXF81089.1 - 8.8e-22 76.8 0.0 3.7e-21 74.8 0.0 2.2 2 0 0 2 2 2 1 MGS-like domain Dala_Dala_lig_C PF07478.8 EXF81089.1 - 7.2e-16 58.1 0.6 1.3e-07 31.1 0.1 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EXF81089.1 - 8.6e-16 57.7 0.1 1.9e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.8 EXF81089.1 - 2.3e-06 27.1 0.1 6.7e-05 22.4 0.0 2.6 1 1 0 1 1 1 1 Peptidase C26 ATP-grasp_3 PF02655.9 EXF81089.1 - 4.3e-06 26.6 0.4 0.037 13.8 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp domain DJ-1_PfpI PF01965.19 EXF81089.1 - 0.0072 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 DJ-1/PfpI family GARS_A PF01071.14 EXF81089.1 - 0.0092 15.5 0.3 2.8 7.4 0.0 2.9 3 0 0 3 3 3 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Pyridox_oxidase PF01243.15 EXF81090.1 - 1.2e-20 73.2 0.0 2e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNPOx_C PF10590.4 EXF81090.1 - 1.9e-20 72.0 1.8 1.9e-20 72.0 1.2 2.1 3 0 0 3 3 3 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.2 EXF81090.1 - 0.00027 21.2 0.0 0.00071 19.8 0.0 1.8 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Cyclin_N PF00134.18 EXF81091.1 - 2.2e-06 27.2 0.0 4.8e-05 22.9 0.0 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Reprolysin_2 PF13574.1 EXF81093.1 - 0.33 11.0 5.8 0.18 11.8 1.2 2.1 1 1 1 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like SnoaL PF07366.7 EXF81096.1 - 6.7e-06 25.6 0.1 0.13 11.7 0.0 2.8 2 1 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EXF81096.1 - 1.3e-05 25.4 0.0 0.016 15.5 0.0 2.2 2 0 0 2 2 2 2 SnoaL-like domain DUF4440 PF14534.1 EXF81096.1 - 0.078 13.1 0.1 0.4 10.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) ENTH PF01417.15 EXF81096.1 - 0.14 12.0 0.1 0.31 10.8 0.0 1.6 2 0 0 2 2 2 0 ENTH domain Methyltransf_23 PF13489.1 EXF81097.1 - 2e-14 53.6 0.0 4.4e-14 52.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF81097.1 - 0.00026 20.6 0.0 0.042 13.4 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EXF81097.1 - 0.035 14.6 0.2 18 5.9 0.0 3.2 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_11 PF08241.7 EXF81097.1 - 0.11 13.0 0.0 0.58 10.6 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 EXF81098.1 - 2.4e-18 66.3 0.0 3.9e-18 65.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF81098.1 - 7.4e-10 38.6 0.0 5.9e-09 35.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF81098.1 - 7.1e-08 32.8 0.0 1.4e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF81098.1 - 2.9e-07 30.8 0.0 2.3e-06 27.9 0.0 2.3 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF81098.1 - 9.3e-07 29.4 0.0 1.2e-05 25.8 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF81098.1 - 0.00063 20.0 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF81098.1 - 0.023 14.0 0.0 0.042 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.15 EXF81098.1 - 0.044 12.8 0.0 0.066 12.2 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF938 PF06080.7 EXF81098.1 - 0.064 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PrmA PF06325.8 EXF81098.1 - 0.075 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EXF81098.1 - 0.081 11.9 0.0 0.14 11.1 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 EXF81098.1 - 0.13 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase DREV PF05219.7 EXF81098.1 - 0.14 10.9 0.0 0.21 10.4 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_23 PF13489.1 EXF81099.1 - 1.5e-22 80.0 0.0 2.3e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF81099.1 - 2e-10 40.4 0.0 2.4e-09 36.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF81099.1 - 4.4e-09 36.7 0.0 8.2e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF81099.1 - 1.3e-07 32.0 0.0 1.9e-06 28.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF81099.1 - 1.6e-07 31.9 0.0 2.4e-06 28.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF81099.1 - 0.00025 21.3 0.0 0.00057 20.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF81099.1 - 0.0026 17.1 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CheR PF01739.13 EXF81099.1 - 0.0044 16.3 0.0 0.0075 15.5 0.0 1.3 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain FtsJ PF01728.14 EXF81099.1 - 0.0058 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PrmA PF06325.8 EXF81099.1 - 0.088 11.9 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 EXF81099.1 - 0.14 11.5 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase NTP_transferase PF00483.18 EXF81100.1 - 0.098 11.9 0.1 0.11 11.7 0.0 1.1 1 0 0 1 1 1 0 Nucleotidyl transferase DUF3551 PF12071.3 EXF81100.1 - 0.11 12.0 0.0 0.15 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3551) ABC_tran PF00005.22 EXF81101.1 - 1.5e-39 135.4 0.0 4.3e-19 69.1 0.0 3.2 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.18 EXF81101.1 - 2.4e-34 119.0 28.5 7.5e-27 94.4 10.7 2.9 2 1 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EXF81101.1 - 4.9e-13 49.6 0.3 0.024 14.6 0.2 4.3 2 2 1 4 4 4 3 AAA domain SMC_N PF02463.14 EXF81101.1 - 2.3e-07 30.2 0.0 0.64 9.2 0.0 4.2 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EXF81101.1 - 6e-07 29.0 0.0 0.0099 15.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EXF81101.1 - 1e-06 28.8 1.1 0.0052 16.7 0.4 2.7 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EXF81101.1 - 4e-06 26.2 0.1 0.13 11.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EXF81101.1 - 6.5e-05 23.3 0.1 0.12 12.6 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EXF81101.1 - 7.5e-05 23.5 0.1 0.42 11.4 0.0 2.7 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EXF81101.1 - 0.00016 21.5 0.0 0.49 10.3 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase MobB PF03205.9 EXF81101.1 - 0.00026 20.7 0.1 0.68 9.6 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.1 EXF81101.1 - 0.0005 20.3 0.2 2.3 8.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.1 EXF81101.1 - 0.00051 20.1 0.8 0.9 9.6 0.0 3.3 3 2 0 3 3 2 2 AAA domain DUF258 PF03193.11 EXF81101.1 - 0.00077 18.6 0.1 1.3 8.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_33 PF13671.1 EXF81101.1 - 0.00088 19.1 0.0 0.21 11.4 0.0 3.1 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EXF81101.1 - 0.0011 17.9 0.0 0.19 10.6 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_10 PF12846.2 EXF81101.1 - 0.0024 17.3 0.0 2.1 7.6 0.0 2.6 2 0 0 2 2 2 2 AAA-like domain Arch_ATPase PF01637.13 EXF81101.1 - 0.0037 16.9 0.0 0.18 11.4 0.0 2.5 3 0 0 3 3 2 1 Archaeal ATPase Miro PF08477.8 EXF81101.1 - 0.004 17.6 0.5 0.45 11.0 0.1 2.7 2 0 0 2 2 2 1 Miro-like protein DUF87 PF01935.12 EXF81101.1 - 0.0068 16.2 0.1 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF87 FtsK_SpoIIIE PF01580.13 EXF81101.1 - 0.0074 15.7 0.0 0.56 9.6 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family ABC_ATPase PF09818.4 EXF81101.1 - 0.0078 14.8 1.1 0.57 8.7 0.1 3.0 3 0 0 3 3 3 1 Predicted ATPase of the ABC class Dynamin_N PF00350.18 EXF81101.1 - 0.016 15.0 1.7 1.5 8.6 0.0 2.5 2 0 0 2 2 2 0 Dynamin family Zeta_toxin PF06414.7 EXF81101.1 - 0.096 11.7 0.0 10 5.1 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.14 EXF81101.1 - 0.11 11.9 0.4 6.8 6.0 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Guanylate_kin PF00625.16 EXF81101.1 - 0.16 11.3 0.2 0.51 9.7 0.0 1.9 2 0 0 2 2 2 0 Guanylate kinase FYVE PF01363.16 EXF81103.1 - 3.3e-14 52.5 8.9 6.1e-14 51.6 6.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger zf-AN1 PF01428.11 EXF81103.1 - 0.0088 15.8 6.3 0.0088 15.8 4.3 1.6 1 1 0 1 1 1 1 AN1-like Zinc finger PhnI PF05861.7 EXF81103.1 - 0.056 11.9 0.0 0.076 11.5 0.0 1.1 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnI) GluR_Homer-bdg PF10606.4 EXF81103.1 - 0.46 10.4 13.4 0.31 10.9 1.8 3.1 3 0 0 3 3 3 0 Homer-binding domain of metabotropic glutamate receptor ELO PF01151.13 EXF81104.1 - 3.1e-83 278.9 10.6 3.9e-83 278.5 7.3 1.1 1 0 0 1 1 1 1 GNS1/SUR4 family GMC_oxred_N PF00732.14 EXF81106.1 - 8.7e-43 146.5 0.8 1.2e-42 146.0 0.6 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF81106.1 - 1.6e-26 93.3 0.4 1.3e-25 90.3 0.0 2.4 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EXF81106.1 - 1.2e-08 34.2 0.3 5.6e-05 22.1 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.12 EXF81106.1 - 9.1e-07 28.1 0.8 0.00013 21.1 0.4 2.3 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EXF81106.1 - 4.1e-06 25.9 3.7 9.5e-06 24.6 2.6 1.6 1 1 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EXF81106.1 - 4.1e-06 26.0 0.1 6.5e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EXF81106.1 - 4.6e-06 26.6 0.3 3e-05 23.9 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF81106.1 - 5.7e-05 23.0 3.8 7.9e-05 22.5 0.7 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EXF81106.1 - 0.0059 15.1 1.1 0.0072 14.8 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein GDI PF00996.13 EXF81106.1 - 0.0088 14.4 0.1 0.014 13.7 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor 3HCDH_N PF02737.13 EXF81106.1 - 0.011 15.3 0.1 0.026 14.1 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EXF81106.1 - 0.031 13.3 1.9 0.051 12.6 1.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 EXF81106.1 - 0.04 12.7 0.4 0.082 11.7 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A UDPG_MGDP_dh_N PF03721.9 EXF81106.1 - 0.093 12.1 1.4 0.15 11.4 1.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pyr_redox PF00070.22 EXF81106.1 - 0.095 13.1 0.3 0.2 12.0 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EXF81106.1 - 0.14 11.7 0.3 0.27 10.8 0.2 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain MoaC PF01967.16 EXF81107.1 - 1.6e-48 163.8 1.7 3.8e-48 162.6 1.2 1.7 1 0 0 1 1 1 1 MoaC family Mob_synth_C PF06463.8 EXF81107.1 - 1.4e-35 121.7 0.0 9.1e-35 119.1 0.0 2.1 1 1 1 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EXF81107.1 - 1.3e-19 70.9 0.0 2.5e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EXF81107.1 - 0.00069 19.7 0.0 0.0017 18.4 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EXF81107.1 - 0.00092 19.2 0.0 0.0044 17.0 0.0 2.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain PhnH PF05845.7 EXF81108.1 - 0.013 14.9 0.3 0.023 14.1 0.2 1.3 1 0 0 1 1 1 0 Bacterial phosphonate metabolism protein (PhnH) WD40 PF00400.27 EXF81108.1 - 0.018 14.9 5.8 25 4.9 0.0 5.5 5 0 0 5 5 5 0 WD domain, G-beta repeat RRM_6 PF14259.1 EXF81109.1 - 0.053 13.5 0.0 0.088 12.7 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) HEAT_2 PF13646.1 EXF81110.1 - 3.6e-14 52.8 8.4 0.003 17.7 0.0 7.0 6 1 1 7 7 7 4 HEAT repeats HEAT PF02985.17 EXF81110.1 - 2.5e-06 27.1 15.1 0.53 10.4 0.0 8.9 11 0 0 11 11 11 2 HEAT repeat Vac14_Fab1_bd PF12755.2 EXF81110.1 - 3.2e-06 27.4 0.0 0.092 13.1 0.0 4.6 4 0 0 4 4 4 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EXF81110.1 - 0.0014 18.0 2.5 3.5 6.9 0.0 4.3 4 0 0 4 4 4 2 CLASP N terminal HEAT_EZ PF13513.1 EXF81110.1 - 0.92 10.0 21.4 27 5.4 0.1 8.4 8 1 1 9 9 9 0 HEAT-like repeat Transcrip_reg PF01709.15 EXF81111.1 - 7.9e-52 175.7 0.1 9.2e-52 175.4 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator Dynamin_N PF00350.18 EXF81114.1 - 9.4e-14 51.5 3.0 1.1e-12 48.0 0.0 3.0 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.18 EXF81114.1 - 3.6e-05 23.6 0.4 0.0026 17.6 0.1 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EXF81114.1 - 0.0004 20.7 0.1 0.0018 18.5 0.0 2.2 2 0 0 2 2 2 1 ABC transporter Miro PF08477.8 EXF81114.1 - 0.00042 20.7 0.0 0.0015 18.9 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein KAP_NTPase PF07693.9 EXF81114.1 - 0.012 14.6 5.0 0.015 14.2 0.0 2.5 3 0 0 3 3 3 0 KAP family P-loop domain DUF258 PF03193.11 EXF81114.1 - 0.014 14.5 0.0 0.043 13.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EXF81114.1 - 0.033 13.7 0.0 0.071 12.6 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EXF81114.1 - 0.05 13.5 0.0 0.28 11.1 0.0 2.3 1 0 0 1 1 1 0 AAA ATPase domain DUF87 PF01935.12 EXF81114.1 - 0.052 13.3 2.5 1.1 9.0 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function DUF87 Syntaxin-6_N PF09177.6 EXF81114.1 - 0.28 11.6 5.5 0.14 12.5 0.5 2.9 3 0 0 3 3 3 0 Syntaxin 6, N-terminal NUDIX_2 PF13869.1 EXF81115.1 - 1.9e-81 271.9 0.0 2.3e-81 271.6 0.0 1.1 1 0 0 1 1 1 1 Nucleotide hydrolase UPF0047 PF01894.12 EXF81116.1 - 2.2e-40 137.1 0.0 2.9e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 zf-CHCC PF10276.4 EXF81117.1 - 3.4e-15 55.5 0.5 4.9e-15 55.0 0.3 1.2 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 EXF81117.1 - 0.014 15.0 0.0 0.025 14.2 0.0 1.5 1 0 0 1 1 1 0 Cytochrome c oxidase subunit Vb zf-C2H2_4 PF13894.1 EXF81117.1 - 0.6 10.5 2.8 0.36 11.2 0.5 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger UCH PF00443.24 EXF81118.1 - 9.9e-75 251.1 0.0 6.8e-74 248.3 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_M16_C PF05193.16 EXF81118.1 - 1.2e-33 116.3 0.0 1.4e-18 67.2 0.0 2.9 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EXF81118.1 - 5.8e-30 104.0 0.2 5.8e-30 104.0 0.1 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) UCH_1 PF13423.1 EXF81118.1 - 2.4e-17 63.3 0.0 3.1e-08 33.4 0.0 2.7 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EXF81118.1 - 1.2e-06 28.8 0.0 4e-06 27.1 0.0 2.0 1 0 0 1 1 1 1 DUSP domain zf-CCHC PF00098.18 EXF81119.1 - 1.3e-06 28.0 4.8 2e-06 27.4 3.3 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EXF81119.1 - 0.0017 17.8 1.1 0.0041 16.5 0.8 1.6 1 0 0 1 1 1 1 Zinc knuckle Nop14 PF04147.7 EXF81119.1 - 0.0073 14.2 13.6 0.0099 13.8 9.4 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 EXF81119.1 - 0.45 8.4 9.6 0.7 7.8 6.7 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF2146 PF10220.4 EXF81119.1 - 9.3 4.0 8.4 14 3.4 5.8 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2146) DAO PF01266.19 EXF81120.1 - 5.1e-54 183.5 0.6 6.2e-54 183.2 0.4 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF81120.1 - 4.1e-06 26.7 0.9 1.6e-05 24.8 0.5 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EXF81120.1 - 0.00049 20.2 0.0 0.45 10.5 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF81120.1 - 0.079 13.3 0.1 6.1 7.3 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF81120.1 - 0.8 8.4 5.1 1.1 8.0 2.4 1.8 2 0 0 2 2 2 0 FAD binding domain MFS_1 PF07690.11 EXF81121.1 - 1.4e-29 102.9 30.0 2.7e-25 88.8 5.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_1 PF00515.23 EXF81122.1 - 1.9e-54 179.1 31.3 4.7e-08 32.3 0.0 10.4 11 1 0 11 11 11 8 Tetratricopeptide repeat TPR_2 PF07719.12 EXF81122.1 - 1.1e-47 156.1 26.4 1.7e-06 27.4 0.0 10.3 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 EXF81122.1 - 6.2e-47 157.1 20.7 1e-13 50.6 0.8 6.3 3 2 1 6 6 6 6 TPR repeat TPR_8 PF13181.1 EXF81122.1 - 4.4e-38 126.1 24.8 5.3e-06 25.8 0.0 10.0 7 2 3 10 10 10 8 Tetratricopeptide repeat TPR_16 PF13432.1 EXF81122.1 - 5.5e-34 116.0 18.5 1.4e-08 35.2 0.0 6.6 3 2 4 7 7 7 7 Tetratricopeptide repeat TPR_12 PF13424.1 EXF81122.1 - 4.5e-31 106.6 23.3 7.3e-07 29.0 0.1 6.7 2 2 4 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 EXF81122.1 - 1e-28 97.1 18.1 9.2e-05 22.7 0.0 9.6 3 2 7 10 10 9 9 Tetratricopeptide repeat TPR_17 PF13431.1 EXF81122.1 - 2.4e-28 95.9 18.1 0.0017 18.3 0.0 10.8 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_19 PF14559.1 EXF81122.1 - 5.1e-25 87.6 17.0 0.00024 21.3 0.1 6.7 5 2 1 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.1 EXF81122.1 - 8.3e-23 78.3 14.3 0.0015 18.1 0.0 9.6 8 1 1 9 9 9 5 Tetratricopeptide repeat TPR_6 PF13174.1 EXF81122.1 - 4e-22 77.0 20.1 0.00068 19.9 0.0 9.9 10 0 0 10 10 10 5 Tetratricopeptide repeat Apc3 PF12895.2 EXF81122.1 - 3.7e-16 59.0 14.9 3.7e-08 33.3 0.8 4.3 4 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EXF81122.1 - 1e-12 47.6 17.1 0.00089 19.0 0.1 6.9 1 1 5 7 7 7 5 Tetratricopeptide repeat TPR_15 PF13429.1 EXF81122.1 - 3.5e-11 42.6 12.6 0.00019 20.5 1.0 5.1 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_20 PF14561.1 EXF81122.1 - 2.7e-05 24.2 4.8 0.28 11.3 0.0 4.0 3 1 1 4 4 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EXF81122.1 - 0.00031 20.5 0.7 25 4.8 0.0 5.2 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 EXF81122.1 - 0.0028 17.5 20.8 0.85 9.6 0.0 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat DUF2225 PF09986.4 EXF81122.1 - 0.0079 15.6 2.4 1.2 8.5 0.2 3.5 1 1 2 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2225) GAS PF13851.1 EXF81122.1 - 0.025 13.7 0.3 0.072 12.2 0.1 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding TPR_21 PF09976.4 EXF81122.1 - 0.039 13.8 0.0 0.039 13.8 0.0 4.9 5 2 2 7 7 5 0 Tetratricopeptide repeat RPN7 PF10602.4 EXF81122.1 - 0.5 9.7 7.4 2.5 7.4 0.2 4.5 5 1 0 5 5 5 0 26S proteasome subunit RPN7 SNAP PF14938.1 EXF81122.1 - 0.81 8.7 16.3 10 5.1 1.0 4.7 1 1 2 4 4 4 0 Soluble NSF attachment protein, SNAP MIT PF04212.13 EXF81122.1 - 1.5 8.8 18.6 3.8 7.4 0.7 5.9 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain Ribosomal_L3 PF00297.17 EXF81123.1 - 3.7e-116 387.1 6.5 4.4e-116 386.8 4.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 Nif11 PF07862.6 EXF81124.1 - 0.08 12.9 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 Nitrogen fixation protein of unknown function Chorismate_bind PF00425.13 EXF81125.1 - 8.8e-88 293.9 0.0 2.6e-87 292.4 0.0 1.7 2 0 0 2 2 2 1 chorismate binding enzyme Anth_synt_I_N PF04715.8 EXF81125.1 - 4.6e-27 94.7 0.1 1.8e-23 83.0 0.0 3.3 3 0 0 3 3 3 2 Anthranilate synthase component I, N terminal region Mycoplasma_p37 PF06646.6 EXF81125.1 - 0.14 11.1 0.2 0.33 9.9 0.0 1.7 2 0 0 2 2 2 0 High affinity transport system protein p37 DUF2065 PF09838.4 EXF81126.1 - 0.0013 18.3 1.8 0.029 14.0 0.1 2.6 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2065) RGS PF00615.14 EXF81126.1 - 0.0024 17.9 0.0 0.004 17.2 0.0 1.5 1 1 0 1 1 1 1 Regulator of G protein signaling domain DUF1625 PF07787.7 EXF81126.1 - 0.092 11.9 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) DUF4184 PF13803.1 EXF81126.1 - 0.14 11.4 1.0 0.23 10.7 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4184) NAD_binding_2 PF03446.10 EXF81127.1 - 9.9e-19 67.7 0.0 1.4e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_hydro_72 PF03198.9 EXF81129.1 - 2.1e-96 322.6 0.1 2.8e-96 322.1 0.0 1.0 1 0 0 1 1 1 1 Glucanosyltransferase Cellulase PF00150.13 EXF81129.1 - 0.00091 18.5 0.5 0.0045 16.2 0.4 2.0 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EXF81129.1 - 0.0029 16.5 0.1 0.018 13.9 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Pkinase PF00069.20 EXF81130.1 - 7.7e-12 44.9 0.0 2.7e-11 43.1 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF81130.1 - 3.7e-07 29.4 0.0 1.2e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF81130.1 - 0.0021 17.0 0.0 0.0036 16.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Sugar_tr PF00083.19 EXF81131.1 - 2.7e-108 362.4 25.2 3.2e-108 362.2 17.4 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF81131.1 - 3.4e-20 72.0 29.1 3.4e-20 72.0 20.2 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily TFIIA_gamma_N PF02268.11 EXF81131.1 - 0.011 15.3 0.0 0.024 14.2 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IIA, gamma subunit, helical domain DUF1324 PF07038.6 EXF81131.1 - 0.022 14.7 0.1 0.15 12.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1324) DUF1269 PF06897.7 EXF81131.1 - 3.4 7.7 6.7 7 6.7 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) MFS_1 PF07690.11 EXF81132.1 - 3.7e-39 134.4 39.8 3.7e-39 134.4 27.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF81132.1 - 2.1e-13 49.6 12.6 2.1e-13 49.6 8.8 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter GFA PF04828.9 EXF81133.1 - 7.9e-09 35.3 0.2 7.9e-09 35.3 0.1 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme A2L_zn_ribbon PF08792.5 EXF81133.1 - 0.073 12.5 0.5 0.073 12.5 0.4 2.6 3 0 0 3 3 3 0 A2L zinc ribbon domain DUF678 PF05077.7 EXF81133.1 - 0.088 12.8 2.8 0.25 11.3 1.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF678) DUF3133 PF11331.3 EXF81133.1 - 0.35 10.4 0.2 0.35 10.4 0.2 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3133) Cys_rich_CWC PF14375.1 EXF81133.1 - 0.73 9.8 4.8 0.24 11.3 0.4 2.1 2 1 0 2 2 2 0 Cysteine-rich CWC Auto_anti-p27 PF06677.7 EXF81133.1 - 0.85 9.4 0.1 0.85 9.4 0.1 3.0 2 1 1 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF2318 PF10080.4 EXF81133.1 - 1.1 9.0 3.8 3.8 7.3 0.2 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2318) adh_short PF00106.20 EXF81134.1 - 1.4e-28 99.9 1.7 2.4e-28 99.1 1.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF81134.1 - 5e-13 49.3 0.0 6.8e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF81134.1 - 2.2e-10 40.5 3.4 1.5e-09 37.7 2.3 2.1 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EXF81134.1 - 0.045 13.7 0.3 0.084 12.8 0.2 1.4 1 0 0 1 1 1 0 NADH(P)-binding WD40 PF00400.27 EXF81135.1 - 8.9e-42 139.5 9.1 2.6e-10 39.7 0.0 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat Sof1 PF04158.9 EXF81135.1 - 2.7e-30 104.2 13.3 5.5e-30 103.2 9.2 1.5 1 0 0 1 1 1 1 Sof1-like domain BBS2_Mid PF14783.1 EXF81135.1 - 0.00014 21.5 0.0 3.1 7.6 0.0 4.5 3 2 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region DUF3312 PF11768.3 EXF81135.1 - 0.0038 15.5 0.0 0.026 12.7 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3312) Cytochrom_D1 PF02239.11 EXF81135.1 - 0.0071 14.6 0.2 0.99 7.6 0.0 3.0 1 1 2 3 3 3 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.6 EXF81135.1 - 0.047 12.4 0.9 0.59 8.8 0.0 2.8 1 1 2 3 3 3 0 Nup133 N terminal like PCI PF01399.22 EXF81136.1 - 1.1e-21 77.0 2.1 1.4e-21 76.7 0.3 2.1 3 0 0 3 3 2 1 PCI domain TPR_8 PF13181.1 EXF81136.1 - 5.2e-06 25.8 0.6 2.6 8.0 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EXF81136.1 - 3.4e-05 23.2 3.5 0.57 10.1 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat DDRGK PF09756.4 EXF81136.1 - 7.2e-05 22.2 0.7 7.2e-05 22.2 0.5 2.0 2 0 0 2 2 2 1 DDRGK domain TPR_1 PF00515.23 EXF81136.1 - 0.0022 17.5 1.4 1.7 8.3 0.1 4.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EXF81136.1 - 0.0028 18.2 10.3 1.4 9.7 0.3 4.0 3 1 0 3 3 3 1 Tetratricopeptide repeat DUF4047 PF13256.1 EXF81136.1 - 0.0053 16.7 0.5 0.013 15.4 0.4 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4047) PCI_Csn8 PF10075.4 EXF81136.1 - 0.012 15.4 1.2 0.029 14.1 0.8 1.7 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 DUF4456 PF14644.1 EXF81136.1 - 0.012 14.8 3.5 0.11 11.6 1.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4456) TPR_12 PF13424.1 EXF81136.1 - 0.017 15.0 15.2 0.42 10.5 0.1 5.2 2 2 4 6 6 6 0 Tetratricopeptide repeat INT_SG_DDX_CT_C PF15300.1 EXF81136.1 - 0.029 13.8 0.0 0.075 12.4 0.0 1.6 1 0 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus TPR_2 PF07719.12 EXF81136.1 - 0.095 12.6 6.9 24 5.1 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat OmpH PF03938.9 EXF81136.1 - 0.11 12.4 7.6 0.07 13.0 0.5 2.3 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) TPR_14 PF13428.1 EXF81136.1 - 0.11 13.1 10.1 28 5.6 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.9 EXF81136.1 - 0.11 12.9 0.2 0.94 10.0 0.0 2.8 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_6 PF13174.1 EXF81136.1 - 0.41 11.2 7.7 31 5.3 0.1 5.2 6 0 0 6 6 4 0 Tetratricopeptide repeat MetRS-N PF09635.5 EXF81136.1 - 1.6 9.1 7.3 0.51 10.7 1.2 2.8 3 2 1 4 4 4 0 MetRS-N binding domain Mito_carr PF00153.22 EXF81138.1 - 1.4e-53 178.5 4.0 3.1e-18 65.2 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 EXF81138.1 - 0.00069 19.3 0.2 0.002 17.8 0.1 1.9 2 0 0 2 2 2 1 UcrQ family DUF2590 PF10761.4 EXF81138.1 - 0.11 12.2 0.0 0.47 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2590) Mak10 PF04112.8 EXF81139.1 - 3.8e-52 175.9 0.0 8.1e-52 174.8 0.0 1.6 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase PEN-2 PF10251.4 EXF81139.1 - 0.043 14.0 0.4 2.2 8.5 0.0 3.1 3 0 0 3 3 3 0 Presenilin enhancer-2 subunit of gamma secretase ATP-synt_Eps PF04627.8 EXF81140.1 - 1.4e-23 82.2 1.0 1.7e-23 81.8 0.7 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain PMBR PF09373.5 EXF81140.1 - 0.078 12.9 0.1 0.12 12.3 0.1 1.3 1 0 0 1 1 1 0 Pseudomurein-binding repeat FAD_binding_3 PF01494.14 EXF81141.1 - 8.8e-20 71.0 0.2 2e-08 33.7 0.0 3.0 2 1 0 2 2 2 2 FAD binding domain SE PF08491.5 EXF81141.1 - 0.00031 19.6 0.0 0.0046 15.8 0.0 2.0 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.1 EXF81141.1 - 0.0008 19.3 0.1 0.0022 17.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EXF81141.1 - 0.0048 15.8 0.2 0.083 11.7 0.0 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein DAO PF01266.19 EXF81141.1 - 0.017 14.0 0.0 0.13 11.1 0.0 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase ApbA PF02558.11 EXF81141.1 - 0.076 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_2 PF07992.9 EXF81141.1 - 0.15 11.9 0.0 0.24 11.2 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase AIP3 PF03915.8 EXF81142.1 - 3.3e-160 533.6 7.4 4.7e-160 533.1 5.1 1.2 1 0 0 1 1 1 1 Actin interacting protein 3 Lectin_N PF03954.9 EXF81142.1 - 0.006 15.9 1.2 0.018 14.4 0.1 2.3 2 0 0 2 2 2 1 Hepatic lectin, N-terminal domain FliL PF03748.9 EXF81142.1 - 0.027 14.4 0.1 0.15 12.0 0.1 2.3 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL NPV_P10 PF05531.7 EXF81142.1 - 0.3 11.3 7.5 0.18 12.0 0.5 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 EXF81142.1 - 1.2 9.0 7.4 1.7 8.4 0.0 3.5 4 0 0 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus Pro_isomerase PF00160.16 EXF81143.1 - 2.1e-42 144.9 0.0 2.4e-42 144.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD MFS_1 PF07690.11 EXF81144.1 - 2.2e-29 102.2 27.7 2.2e-29 102.2 19.2 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2207 PF09972.4 EXF81144.1 - 0.31 9.5 0.0 0.31 9.5 0.0 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) HSF_DNA-bind PF00447.12 EXF81145.1 - 1.2e-28 99.2 0.2 3.2e-28 97.9 0.2 1.7 1 0 0 1 1 1 1 HSF-type DNA-binding Pro_isomerase PF00160.16 EXF81146.1 - 4.9e-40 137.2 0.0 9.8e-40 136.2 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD vMSA PF00695.14 EXF81147.1 - 1.8 7.7 7.5 2.9 6.9 5.2 1.4 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus DS PF01916.12 EXF81148.1 - 4.1e-141 469.3 0.0 4.7e-141 469.1 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Arrestin_C PF02752.17 EXF81150.1 - 1.9e-15 57.1 0.1 2.2e-14 53.6 0.1 2.2 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Trs65 PF12735.2 EXF81150.1 - 0.028 13.7 0.3 0.12 11.6 0.1 2.0 1 1 1 2 2 2 0 TRAPP trafficking subunit Trs65 adh_short PF00106.20 EXF81151.1 - 1.5e-12 47.7 0.0 2.7e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EXF81151.1 - 0.0012 18.3 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EXF81151.1 - 0.0055 16.4 0.0 0.0075 16.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF81151.1 - 0.008 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 KR domain ORC6 PF05460.8 EXF81152.1 - 8.9e-40 136.8 0.0 1.2e-39 136.4 0.0 1.2 1 0 0 1 1 1 1 Origin recognition complex subunit 6 (ORC6) EF-hand_6 PF13405.1 EXF81153.1 - 5.2e-05 22.7 0.3 0.095 12.6 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EXF81153.1 - 0.0023 17.0 0.1 0.011 15.0 0.0 2.1 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.1 EXF81153.1 - 0.0047 16.2 0.1 0.019 14.3 0.0 1.9 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.1 EXF81153.1 - 0.01 15.9 1.8 0.03 14.4 1.2 1.8 1 1 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.1 EXF81153.1 - 0.082 12.5 0.1 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 EF-hand domain pair Met_10 PF02475.11 EXF81154.1 - 1.9e-05 24.3 0.0 0.00014 21.5 0.0 2.0 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_26 PF13659.1 EXF81154.1 - 0.0037 17.2 0.0 0.007 16.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Rpr2 PF04032.11 EXF81155.1 - 3.1e-09 36.5 0.4 3.1e-09 36.5 0.3 1.7 2 0 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF3133 PF11331.3 EXF81155.1 - 0.0018 17.7 1.2 0.33 10.5 0.1 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF3133) GFA PF04828.9 EXF81155.1 - 0.28 11.1 1.8 1.1 9.2 0.0 2.3 1 1 2 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 EXF81155.1 - 0.38 10.4 2.1 0.81 9.4 0.2 2.1 2 0 0 2 2 2 0 Nudix N-terminal DNA_pol_viral_N PF00242.12 EXF81155.1 - 0.57 9.1 7.0 0.65 8.9 4.9 1.1 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain TRAUB PF08164.7 EXF81155.1 - 0.67 10.0 0.1 0.67 10.0 0.1 2.3 2 0 0 2 2 2 0 Apoptosis-antagonizing transcription factor, C-terminal zf-ZPR1 PF03367.8 EXF81156.1 - 6.5e-106 350.4 0.0 9.5e-53 177.6 0.0 2.2 2 0 0 2 2 2 2 ZPR1 zinc-finger domain Di19_C PF14571.1 EXF81156.1 - 0.093 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal Pirin PF02678.11 EXF81159.1 - 2.7e-24 85.0 1.3 8.1e-24 83.5 0.9 1.8 1 1 0 1 1 1 1 Pirin Cupin_2 PF07883.6 EXF81159.1 - 0.00024 20.5 5.6 0.027 13.9 0.8 3.3 3 1 0 3 3 3 2 Cupin domain DUF4480 PF13715.1 EXF81159.1 - 0.093 12.7 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4480) Yae1_N PF09811.4 EXF81160.1 - 3e-13 49.0 1.6 5.4e-13 48.2 1.1 1.4 1 0 0 1 1 1 1 Essential protein Yae1, N terminal P53_TAD PF08563.6 EXF81160.1 - 0.12 11.4 0.3 0.22 10.6 0.2 1.4 1 0 0 1 1 1 0 P53 transactivation motif CENP-O PF09496.5 EXF81162.1 - 4.4e-24 84.5 0.0 8e-24 83.6 0.0 1.4 1 0 0 1 1 1 1 Cenp-O kinetochore centromere component Acatn PF13000.2 EXF81163.1 - 1.4e-153 512.3 24.3 1.4e-78 264.8 6.0 3.1 1 1 2 3 3 3 3 Acetyl-coenzyme A transporter 1 DFP PF04127.10 EXF81164.1 - 4.5e-15 55.7 0.0 1e-05 25.2 0.0 3.3 2 1 1 3 3 3 3 DNA / pantothenate metabolism flavoprotein MFS_1 PF07690.11 EXF81165.1 - 4e-41 140.8 75.9 9.6e-38 129.7 34.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF81165.1 - 7.8e-12 44.4 45.3 6.4e-07 28.3 14.4 2.5 2 2 0 2 2 2 2 Sugar (and other) transporter DUF872 PF05915.7 EXF81165.1 - 4.9 7.0 0.0 4.9 7.0 0.0 3.4 3 1 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) GMC_oxred_N PF00732.14 EXF81166.1 - 7.7e-56 189.4 0.0 1e-55 188.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF81166.1 - 5.1e-31 107.8 0.0 7.6e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EXF81166.1 - 8e-05 21.7 0.0 0.001 18.0 0.0 2.5 3 0 0 3 3 3 1 Lycopene cyclase protein DAO PF01266.19 EXF81166.1 - 0.00014 20.8 0.0 0.34 9.7 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF81166.1 - 0.00086 19.2 0.0 0.7 9.7 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF81166.1 - 0.022 14.7 0.2 0.077 13.0 0.0 2.0 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EXF81166.1 - 0.08 11.7 0.0 2.6 6.8 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain TfuA PF07812.7 EXF81167.1 - 0.076 12.4 2.8 0.1 12.0 0.9 1.8 2 0 0 2 2 2 0 TfuA-like protein MFS_1 PF07690.11 EXF81169.1 - 7.2e-22 77.5 21.3 7.2e-22 77.5 14.8 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF81169.1 - 6.7e-06 24.9 34.2 0.00015 20.5 23.7 3.0 1 1 0 1 1 1 1 Sugar (and other) transporter FA_desaturase PF00487.19 EXF81169.1 - 0.28 10.5 9.3 0.096 12.1 0.4 2.6 1 1 1 2 2 2 0 Fatty acid desaturase Lyase_1 PF00206.15 EXF81170.1 - 7.3e-25 87.8 0.2 1.7e-24 86.5 0.2 1.6 1 0 0 1 1 1 1 Lyase ASL_C2 PF14698.1 EXF81170.1 - 1.2e-06 28.5 0.0 3e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal HTH_AsnC-type PF13404.1 EXF81170.1 - 0.14 11.6 0.8 0.95 9.0 0.1 2.5 2 0 0 2 2 2 0 AsnC-type helix-turn-helix domain Abhydrolase_5 PF12695.2 EXF81171.1 - 7.2e-06 25.8 0.0 1.1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EXF81171.1 - 8e-06 25.5 0.7 4.6e-05 23.0 0.0 2.1 2 1 0 2 2 2 1 alpha/beta hydrolase fold Lipase_3 PF01764.20 EXF81171.1 - 1.1e-05 25.0 0.0 0.00028 20.4 0.0 2.3 1 1 0 1 1 1 1 Lipase (class 3) DUF915 PF06028.6 EXF81171.1 - 4.9e-05 22.5 0.0 8.5e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.2 EXF81171.1 - 0.0003 20.7 0.3 0.00098 19.0 0.2 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF81171.1 - 0.0041 16.7 0.1 0.31 10.5 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold DUF2974 PF11187.3 EXF81171.1 - 0.069 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Thioesterase PF00975.15 EXF81171.1 - 0.097 12.8 0.0 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 Thioesterase domain TPR_12 PF13424.1 EXF81172.1 - 4.6e-23 80.9 13.6 5.7e-05 22.9 0.2 8.0 5 3 5 10 10 10 8 Tetratricopeptide repeat TPR_10 PF13374.1 EXF81172.1 - 3.4e-19 68.1 18.1 0.11 12.5 0.1 9.9 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.1 EXF81172.1 - 1.5e-10 41.4 3.8 1.3 9.7 0.0 6.8 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 EXF81172.1 - 8.3e-10 38.4 3.8 2 9.2 0.0 7.1 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 EXF81172.1 - 5e-09 35.4 1.9 4.4 7.4 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 EXF81172.1 - 7.4e-09 34.7 0.9 0.081 12.7 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 EXF81172.1 - 1.3e-08 34.3 1.3 0.01 15.4 0.0 5.4 5 0 0 5 5 5 1 TPR repeat TPR_19 PF14559.1 EXF81172.1 - 3.9e-07 30.2 4.2 3.8 7.9 0.0 7.0 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 EXF81172.1 - 2.4e-06 26.9 0.3 9 6.1 0.0 5.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_4 PF07721.9 EXF81172.1 - 4.2e-06 26.6 8.0 2 9.1 0.1 6.7 7 0 0 7 7 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EXF81172.1 - 0.00089 19.3 0.1 0.34 11.0 0.0 4.4 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EXF81172.1 - 0.034 14.6 1.3 1.7e+02 2.9 0.0 5.9 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_5 PF12688.2 EXF81172.1 - 0.042 13.8 3.4 11 6.0 0.2 3.7 2 2 1 3 3 3 0 Tetratrico peptide repeat DUF346 PF03984.8 EXF81172.1 - 0.047 13.1 0.0 3.3 7.2 0.0 2.7 2 0 0 2 2 2 0 Repeat of unknown function (DUF346) 3Beta_HSD PF01073.14 EXF81173.1 - 4.1e-57 193.0 0.0 5.3e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EXF81173.1 - 1.4e-34 119.5 0.0 1.8e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EXF81173.1 - 8.7e-20 70.6 0.1 6.6e-13 48.1 0.0 2.1 1 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EXF81173.1 - 3.8e-15 55.5 0.1 5.3e-15 55.0 0.1 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.20 EXF81173.1 - 2.2e-12 47.2 0.9 5.2e-12 45.9 0.6 1.6 1 1 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EXF81173.1 - 8.2e-12 45.4 0.1 1.2e-11 44.9 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EXF81173.1 - 2e-10 40.0 0.4 8.1e-09 34.7 0.6 2.7 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.5 EXF81173.1 - 9.9e-08 31.8 1.1 9.9e-08 31.8 0.8 2.2 2 1 0 2 2 2 1 KR domain Exo_endo_phos PF03372.18 EXF81174.1 - 1.4e-20 74.2 0.0 2.5e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family LRR_4 PF12799.2 EXF81174.1 - 1.8e-13 49.7 3.7 5.1e-07 29.1 0.2 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EXF81174.1 - 4.7e-09 35.8 5.8 3e-05 23.6 0.1 2.5 2 1 2 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 EXF81174.1 - 0.00088 18.9 5.3 0.22 11.7 0.0 4.3 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_7 PF13504.1 EXF81174.1 - 0.062 13.5 2.5 32 5.3 0.0 4.0 3 0 0 3 3 3 0 Leucine rich repeat Methyltransf_25 PF13649.1 EXF81175.1 - 2.8e-13 50.1 0.0 5e-13 49.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF81175.1 - 2e-09 37.8 0.0 4.9e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF81175.1 - 3.3e-08 33.4 0.0 8.7e-08 32.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF81175.1 - 2.2e-06 28.1 0.0 4.8e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF81175.1 - 4.5e-05 23.0 0.0 0.00012 21.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF81175.1 - 5.2e-05 23.2 0.0 0.00017 21.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF81175.1 - 0.00062 20.1 0.0 0.0015 18.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF81175.1 - 0.0011 18.1 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EXF81175.1 - 0.011 15.6 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_32 PF13679.1 EXF81175.1 - 0.13 11.9 0.0 0.33 10.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 EXF81175.1 - 0.28 10.7 0.0 0.44 10.1 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase PAT1 PF09770.4 EXF81175.1 - 2.1 6.4 15.7 3.1 5.9 10.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ceramidase PF05875.7 EXF81177.1 - 0.06 12.4 0.6 0.095 11.8 0.0 1.5 2 0 0 2 2 2 0 Ceramidase CENP-Q PF13094.1 EXF81177.1 - 0.35 10.8 23.2 1.1 9.2 7.6 2.5 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4200 PF13863.1 EXF81177.1 - 2.6 8.0 35.1 0.78 9.6 12.0 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) Mcm10 PF09332.6 EXF81178.1 - 5.5 6.2 9.4 6.4 6.0 6.5 1.0 1 0 0 1 1 1 0 Mcm10 replication factor DASH_Ask1 PF08655.5 EXF81179.1 - 2.4e-33 113.7 0.1 3.8e-33 113.1 0.1 1.3 1 0 0 1 1 1 1 DASH complex subunit Ask1 YqfQ PF14181.1 EXF81179.1 - 0.013 15.5 0.5 0.032 14.2 0.0 1.9 2 0 0 2 2 2 0 YqfQ-like protein SBF2 PF12335.3 EXF81179.1 - 0.11 11.7 0.3 0.2 10.9 0.2 1.4 1 0 0 1 1 1 0 Myotubularin protein Spc97_Spc98 PF04130.8 EXF81180.1 - 9.9e-76 255.1 0.1 1.2e-75 254.8 0.0 1.0 1 0 0 1 1 1 1 Spc97 / Spc98 family Eaf7 PF07904.8 EXF81181.1 - 1.9e-26 91.8 0.2 4.8e-26 90.5 0.1 1.7 1 0 0 1 1 1 1 Chromatin modification-related protein EAF7 CDC27 PF09507.5 EXF81181.1 - 0.75 8.9 29.2 1.2 8.3 20.3 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Nop14 PF04147.7 EXF81181.1 - 1.3 6.9 40.0 2.2 6.0 27.7 1.3 1 0 0 1 1 1 0 Nop14-like family Mitofilin PF09731.4 EXF81181.1 - 2 6.9 13.1 2.5 6.6 9.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Myb_DNA-binding PF00249.26 EXF81182.1 - 0.00099 19.1 0.0 0.092 12.8 0.0 3.3 3 0 0 3 3 3 1 Myb-like DNA-binding domain ResIII PF04851.10 EXF81183.1 - 3.8e-24 85.5 0.0 7.6e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EXF81183.1 - 4.9e-17 61.5 0.1 1.8e-16 59.7 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EXF81183.1 - 1.6e-12 47.2 0.0 4.3e-12 45.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2075 PF09848.4 EXF81183.1 - 0.0031 16.5 0.0 0.0057 15.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Helicase_C_2 PF13307.1 EXF81183.1 - 0.023 14.6 0.1 0.15 12.0 0.0 2.3 3 0 0 3 3 3 0 Helicase C-terminal domain KH_1 PF00013.24 EXF81184.1 - 9.9e-27 92.3 0.3 1.2e-07 31.2 0.2 8.0 8 0 0 8 8 8 4 KH domain KH_3 PF13014.1 EXF81184.1 - 7e-24 83.0 1.8 3.8e-05 23.2 0.0 5.7 5 0 0 5 5 5 5 KH domain HAD_2 PF13419.1 EXF81186.1 - 2.4e-34 119.0 0.1 3.2e-34 118.6 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EXF81186.1 - 1.4e-07 32.1 0.0 2.8e-07 31.1 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EXF81186.1 - 2.2e-05 24.0 0.0 3.8e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Med21 PF11221.3 EXF81187.1 - 1.5e-45 154.6 5.1 1.7e-45 154.5 3.6 1.0 1 0 0 1 1 1 1 Subunit 21 of Mediator complex Med9 PF07544.8 EXF81187.1 - 0.00098 18.8 0.4 0.00098 18.8 0.3 2.9 2 1 1 4 4 4 2 RNA polymerase II transcription mediator complex subunit 9 GAS PF13851.1 EXF81187.1 - 0.0011 18.1 4.2 0.4 9.8 0.9 2.1 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding CENP-Q PF13094.1 EXF81187.1 - 0.0045 17.0 2.9 0.0045 17.0 2.0 1.5 2 0 0 2 2 2 1 CENP-Q, a CENPA-CAD centromere complex subunit DUF3802 PF12290.3 EXF81187.1 - 0.017 15.4 1.6 0.044 14.0 0.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3802) NYD-SP28 PF14772.1 EXF81187.1 - 0.031 14.3 1.7 0.079 13.0 1.2 1.7 1 0 0 1 1 1 0 Sperm tail TMCO5 PF14992.1 EXF81187.1 - 0.035 13.2 2.7 0.039 13.0 1.9 1.2 1 0 0 1 1 1 0 TMCO5 family Fib_alpha PF08702.5 EXF81187.1 - 0.075 13.1 0.8 0.19 11.8 0.3 1.9 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Spore_III_AB PF09548.5 EXF81187.1 - 0.19 11.4 0.8 0.31 10.7 0.6 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) APG6 PF04111.7 EXF81187.1 - 1.1 8.2 4.2 1.3 8.0 2.9 1.3 1 1 0 1 1 1 0 Autophagy protein Apg6 TMF_DNA_bd PF12329.3 EXF81187.1 - 1.5 8.7 9.0 2.6 7.9 4.6 2.3 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF2034 PF10356.4 EXF81188.1 - 1.5e-29 102.4 0.0 9.5e-15 54.2 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2034) Mrr_cat PF04471.7 EXF81188.1 - 9.8e-07 28.5 0.0 1.9e-06 27.6 0.0 1.4 1 0 0 1 1 1 1 Restriction endonuclease DUF3176 PF11374.3 EXF81189.1 - 1.2e-19 70.2 1.4 7e-18 64.5 0.2 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3176) Cullin PF00888.17 EXF81190.1 - 1.6e-204 680.8 11.4 2.2e-204 680.3 7.9 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EXF81190.1 - 7.7e-27 92.9 5.5 7.7e-27 92.9 3.8 3.0 4 0 0 4 4 4 1 Cullin protein neddylation domain WGG PF10273.4 EXF81190.1 - 0.87 9.7 4.3 14 5.8 0.0 3.9 4 0 0 4 4 4 0 Pre-rRNA-processing protein TSR2 Bcl-2_3 PF15286.1 EXF81191.1 - 0.0065 16.9 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like ABA_GPCR PF12430.3 EXF81191.1 - 0.086 11.9 1.0 0.84 8.7 0.1 2.0 1 1 1 2 2 2 0 Abscisic acid G-protein coupled receptor MARVEL PF01284.18 EXF81191.1 - 0.17 11.7 3.9 0.26 11.0 2.7 1.3 1 0 0 1 1 1 0 Membrane-associating domain Mit_KHE1 PF10173.4 EXF81192.1 - 1.1e-63 214.5 0.1 1.1e-63 214.5 0.1 1.4 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related Sensor PF13796.1 EXF81192.1 - 0.058 12.9 0.1 0.089 12.3 0.1 1.2 1 0 0 1 1 1 0 Putative sensor GATA PF00320.22 EXF81193.1 - 6.4e-15 54.2 4.1 9.6e-15 53.6 1.9 2.0 2 0 0 2 2 2 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 EXF81193.1 - 0.061 12.6 0.4 0.1 11.9 0.3 1.3 1 0 0 1 1 1 0 TFIIB zinc-binding ArfGap PF01412.13 EXF81193.1 - 0.062 13.0 0.2 0.13 12.0 0.1 1.5 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf LcrG PF07216.7 EXF81193.1 - 3.5 7.7 7.7 0.14 12.2 0.2 2.4 2 1 0 2 2 2 0 LcrG protein CENP-F_leu_zip PF10473.4 EXF81193.1 - 8.3 6.2 18.3 0.16 11.8 1.6 2.7 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 KH_1 PF00013.24 EXF81194.1 - 0.0044 16.6 0.0 0.009 15.6 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_3 PF13014.1 EXF81194.1 - 0.057 13.0 0.0 0.14 11.8 0.0 1.7 1 0 0 1 1 1 0 KH domain Pfg27 PF09216.5 EXF81194.1 - 0.066 12.7 0.1 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Pfg27 ADH_zinc_N PF00107.21 EXF81196.1 - 5.1e-22 77.8 0.3 7.8e-22 77.2 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF81196.1 - 5.8e-10 40.1 0.5 1.5e-09 38.8 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF81196.1 - 0.00015 21.5 0.0 0.00039 20.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Sulf_transp PF04143.9 EXF81197.1 - 1.9e-12 47.0 30.4 2.7e-10 40.0 8.8 4.9 4 2 1 5 5 5 2 Sulphur transport DUF4341 PF14241.1 EXF81197.1 - 0.0026 17.4 4.1 0.0026 17.4 2.8 4.9 4 2 0 5 5 5 1 Domain of unknown function (DUF4341) Ank_2 PF12796.2 EXF81198.1 - 5.3e-52 174.1 1.2 1.9e-14 53.7 0.0 5.6 1 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EXF81198.1 - 2.2e-40 134.4 7.2 0.00021 20.9 0.0 10.6 10 1 0 10 10 10 8 Ankyrin repeat Ank_4 PF13637.1 EXF81198.1 - 1.4e-37 127.3 4.3 1.4e-05 25.4 0.0 7.7 4 3 3 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF81198.1 - 9e-35 115.2 2.0 0.012 15.7 0.0 10.2 9 1 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.1 EXF81198.1 - 4.9e-28 96.5 9.1 1.3e-07 31.5 0.0 7.8 2 2 6 9 9 9 8 Ankyrin repeats (many copies) DUF1365 PF07103.6 EXF81198.1 - 0.022 13.8 0.2 0.074 12.0 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1365) Shigella_OspC PF06128.6 EXF81198.1 - 0.12 11.8 0.0 2.1 7.7 0.0 2.3 1 1 1 2 2 2 0 Shigella flexneri OspC protein SAP PF02037.22 EXF81199.1 - 1.1e-07 31.2 0.1 2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 SAP domain zf-RING_2 PF13639.1 EXF81199.1 - 5.9e-05 22.8 11.9 5.9e-05 22.8 8.2 1.7 2 0 0 2 2 2 1 Ring finger domain PHD PF00628.24 EXF81199.1 - 0.0086 15.7 12.0 0.018 14.7 8.3 1.6 1 0 0 1 1 1 1 PHD-finger Vps39_2 PF10367.4 EXF81199.1 - 0.25 11.5 2.2 0.53 10.4 0.6 2.2 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.1 EXF81199.1 - 1 9.1 15.2 0.32 10.7 7.8 2.1 2 0 0 2 2 2 0 zinc-RING finger domain Prok-RING_1 PF14446.1 EXF81199.1 - 1.1 9.0 13.2 3 7.6 9.1 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 EXF81199.1 - 2.4 7.9 13.8 0.22 11.3 5.4 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_3 PF13920.1 EXF81199.1 - 4 7.1 14.5 0.092 12.4 5.5 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Ribonuc_L-PSP PF01042.16 EXF81200.1 - 2.3e-27 95.1 0.3 2.6e-27 95.0 0.2 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP DUF1320 PF07030.7 EXF81200.1 - 0.0019 17.9 0.0 0.0027 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1320) TMEM138 PF14935.1 EXF81201.1 - 0.11 12.8 0.3 0.15 12.4 0.2 1.1 1 0 0 1 1 1 0 Transmembrane protein 138 DUF500 PF04366.7 EXF81202.1 - 8e-26 89.9 0.0 1.7e-25 88.9 0.0 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF500) Actin PF00022.14 EXF81203.1 - 5e-16 58.1 0.0 2.4e-14 52.5 0.0 2.6 3 0 0 3 3 3 2 Actin Fungal_trans PF04082.13 EXF81205.1 - 4.5e-14 51.9 0.5 8.6e-14 51.0 0.3 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EXF81205.1 - 2.6e-07 30.5 7.8 1.3e-05 25.2 0.8 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EXF81205.1 - 4e-05 23.6 14.2 0.0016 18.6 4.2 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-Di19 PF05605.7 EXF81205.1 - 0.0015 18.5 3.8 0.0031 17.5 2.6 1.5 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding zf-C2H2 PF00096.21 EXF81205.1 - 0.018 15.3 16.8 0.053 13.8 4.7 2.9 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.3 EXF81205.1 - 0.7 10.1 3.6 8.2 6.7 0.5 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-BED PF02892.10 EXF81205.1 - 1.7 8.4 7.2 0.8 9.5 0.7 2.4 2 0 0 2 2 2 0 BED zinc finger SBP_bac_6 PF13343.1 EXF81206.1 - 2.2e-13 50.0 1.4 3.3e-13 49.5 1.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.1 EXF81206.1 - 1.9e-07 30.9 0.0 3.5e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.20 EXF81206.1 - 0.00085 19.1 7.6 0.0021 17.8 4.8 2.0 1 1 1 2 2 2 1 Bacterial extracellular solute-binding protein Aminotran_1_2 PF00155.16 EXF81207.1 - 3e-46 158.0 0.0 3.6e-46 157.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Arrestin_C PF02752.17 EXF81208.1 - 1.2e-16 61.0 0.0 5.2e-16 58.9 0.0 2.1 1 1 0 1 1 1 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EXF81208.1 - 1.2e-08 34.9 0.1 0.00033 20.5 0.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain NUDIX PF00293.23 EXF81209.1 - 6.8e-14 51.6 1.0 1.1e-13 50.9 0.7 1.2 1 0 0 1 1 1 1 NUDIX domain DUF972 PF06156.8 EXF81211.1 - 0.00015 22.1 8.5 0.088 13.1 1.5 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF972) DivIC PF04977.10 EXF81211.1 - 0.00073 18.9 5.7 0.0031 16.9 0.3 2.4 2 0 0 2 2 2 1 Septum formation initiator DUF4201 PF13870.1 EXF81211.1 - 0.0012 18.2 6.7 0.023 14.1 0.1 2.4 2 1 1 3 3 3 2 Domain of unknown function (DUF4201) HAP1_N PF04849.8 EXF81211.1 - 0.0032 16.4 3.3 0.0053 15.7 2.3 1.3 1 0 0 1 1 1 1 HAP1 N-terminal conserved region IncA PF04156.9 EXF81211.1 - 0.0051 16.4 9.2 0.015 14.8 0.6 2.3 1 1 1 2 2 2 1 IncA protein Rab5-bind PF09311.6 EXF81211.1 - 0.0063 16.4 10.5 0.094 12.5 1.3 2.4 2 0 0 2 2 2 2 Rabaptin-like protein Filament PF00038.16 EXF81211.1 - 0.011 15.2 4.8 0.29 10.5 0.6 2.2 2 0 0 2 2 2 0 Intermediate filament protein ADIP PF11559.3 EXF81211.1 - 0.023 14.6 13.4 0.57 10.0 0.8 2.3 1 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4398 PF14346.1 EXF81211.1 - 0.036 14.1 4.6 0.081 12.9 3.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4398) HALZ PF02183.13 EXF81211.1 - 0.064 12.9 11.2 0.76 9.5 1.0 3.7 4 0 0 4 4 4 0 Homeobox associated leucine zipper Seadorna_VP6 PF07407.6 EXF81211.1 - 0.075 11.7 0.5 0.1 11.3 0.3 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein DUF1875 PF08961.5 EXF81211.1 - 0.17 11.1 3.4 0.63 9.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1875) FUSC PF04632.7 EXF81211.1 - 0.44 8.9 7.6 0.084 11.2 2.0 1.8 1 1 1 2 2 2 0 Fusaric acid resistance protein family CASP_C PF08172.7 EXF81211.1 - 0.76 8.7 11.6 1.8 7.4 8.0 1.6 1 1 0 1 1 1 0 CASP C terminal bZIP_1 PF00170.16 EXF81211.1 - 1.4 8.9 8.2 0.24 11.3 1.3 2.6 3 0 0 3 3 3 0 bZIP transcription factor GAS PF13851.1 EXF81211.1 - 1.4 8.0 8.8 3 6.9 6.0 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding CALCOCO1 PF07888.6 EXF81211.1 - 4.1 5.5 10.1 0.3 9.3 1.5 2.1 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Cad PF03596.8 EXF81213.1 - 0.058 13.0 0.0 0.076 12.7 0.0 1.1 1 0 0 1 1 1 0 Cadmium resistance transporter PIG-L PF02585.12 EXF81214.1 - 4.3e-09 36.9 0.0 7.3e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase RXT2_N PF08595.6 EXF81214.1 - 0.19 11.5 0.7 0.32 10.7 0.5 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal ATP13 PF12921.2 EXF81215.1 - 2.1e-13 49.7 0.0 3.9e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ATPase expression LSM PF01423.17 EXF81216.1 - 9.4e-18 63.5 0.2 1.2e-17 63.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain Mg296 PF09644.5 EXF81216.1 - 0.046 13.5 0.3 0.057 13.2 0.2 1.3 1 1 0 1 1 1 0 Mg296 protein EF-1_beta_acid PF10587.4 EXF81216.1 - 0.71 10.0 5.5 1.5 9.0 3.6 1.7 2 0 0 2 2 2 0 Eukaryotic elongation factor 1 beta central acidic region GTP_EFTU PF00009.22 EXF81217.1 - 1.1e-21 77.1 0.0 2.2e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EXF81217.1 - 2.7e-14 53.1 0.0 6e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EXF81217.1 - 6e-10 39.0 0.6 6.8e-09 35.7 0.3 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EXF81217.1 - 0.00037 20.4 0.1 0.0012 18.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EXF81217.1 - 0.0006 19.3 0.2 0.33 10.4 0.1 3.3 2 1 1 3 3 3 1 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EXF81217.1 - 0.00062 20.2 0.1 0.018 15.5 0.1 3.0 2 1 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 EXF81217.1 - 0.033 13.3 0.1 0.066 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EXF81217.1 - 0.045 13.5 0.8 0.13 12.0 0.1 2.1 3 0 0 3 3 3 0 Dynamin family GTP_EFTU_D4 PF14578.1 EXF81217.1 - 0.12 12.0 2.5 0.23 11.1 0.3 2.6 3 1 0 3 3 3 0 Elongation factor Tu domain 4 Zn_clus PF00172.13 EXF81218.1 - 9.5e-08 31.8 7.0 1.7e-07 31.0 4.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Cys_rich_VLP PF14194.1 EXF81218.1 - 0.012 15.2 2.4 0.025 14.2 1.7 1.5 1 0 0 1 1 1 0 Cysteine-rich VLP DUF3433 PF11915.3 EXF81219.1 - 2.7e-37 126.7 10.6 2.8e-22 78.6 0.4 3.4 4 0 0 4 4 4 2 Protein of unknown function (DUF3433) DUF2360 PF10152.4 EXF81220.1 - 3.3 7.9 9.7 6.8 6.9 6.7 1.6 1 1 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF3433 PF11915.3 EXF81221.1 - 5.8e-21 74.4 20.7 9.6e-17 60.9 1.4 3.3 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) CBM_19 PF03427.8 EXF81222.1 - 0.85 9.4 6.8 0.13 12.0 1.3 1.9 2 0 0 2 2 2 0 Carbohydrate binding domain (family 19) zf-tcix PF14952.1 EXF81223.1 - 0.04 13.2 3.1 0.071 12.4 2.2 1.4 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Nha1_C PF08619.5 EXF81224.1 - 1.6e-80 271.5 27.7 2e-80 271.1 19.2 1.1 1 0 0 1 1 1 1 Alkali metal cation/H+ antiporter Nha1 C terminus Na_H_Exchanger PF00999.16 EXF81224.1 - 6.6e-67 225.6 23.3 7.9e-67 225.4 16.2 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Pyr_redox_3 PF13738.1 EXF81227.1 - 1.4e-16 61.1 0.0 5.4e-16 59.2 0.0 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF81227.1 - 1e-13 50.9 0.0 1.8e-12 46.8 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EXF81227.1 - 1.4e-10 40.0 0.0 2e-10 39.4 0.0 1.1 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EXF81227.1 - 1.3e-06 28.4 0.0 2.1e-06 27.7 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF81227.1 - 5.9e-05 22.8 0.1 0.028 14.1 0.0 3.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EXF81227.1 - 7.3e-05 22.7 0.0 0.0002 21.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF81227.1 - 0.013 14.4 0.0 4.3 6.1 0.0 3.1 4 0 0 4 4 4 0 FAD dependent oxidoreductase Thi4 PF01946.12 EXF81227.1 - 0.032 13.3 0.3 0.098 11.7 0.0 1.9 3 0 0 3 3 3 0 Thi4 family FAD_binding_2 PF00890.19 EXF81227.1 - 0.038 12.8 0.0 0.56 8.9 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.16 EXF81227.1 - 0.14 11.6 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trypsin_2 PF13365.1 EXF81228.1 - 1.1e-15 57.7 0.0 1.6e-15 57.1 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Peptidase_C4 PF00863.14 EXF81228.1 - 3.3e-05 22.9 0.7 0.0025 16.8 0.0 2.6 2 1 1 3 3 3 1 Peptidase family C4 Peptidase_S32 PF05579.8 EXF81228.1 - 0.019 13.9 0.3 0.039 12.9 0.1 1.5 2 0 0 2 2 2 0 Equine arteritis virus serine endopeptidase S32 Peptidase_S46 PF10459.4 EXF81228.1 - 0.026 12.9 0.0 0.13 10.6 0.0 1.8 2 0 0 2 2 2 0 Peptidase S46 DUF4388 PF14332.1 EXF81228.1 - 0.12 12.1 0.0 0.31 10.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4388) Dynamin_N PF00350.18 EXF81231.1 - 9e-17 61.4 0.2 2.1e-16 60.2 0.0 1.7 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EXF81231.1 - 6.8e-10 38.9 0.2 4.4e-09 36.3 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EXF81231.1 - 7.6e-07 28.7 0.7 7.6e-06 25.4 0.5 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EXF81231.1 - 0.015 14.7 0.1 0.08 12.4 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EXF81231.1 - 0.043 14.1 0.0 0.13 12.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EXF81231.1 - 0.08 13.4 0.0 0.81 10.1 0.0 2.6 1 1 0 1 1 1 0 Miro-like protein Snf7 PF03357.16 EXF81232.1 - 2.5e-21 75.7 30.7 8.8e-16 57.7 9.0 2.3 2 1 1 3 3 3 2 Snf7 CaMBD PF02888.11 EXF81232.1 - 0.00032 20.4 1.9 0.00073 19.3 1.4 1.6 1 0 0 1 1 1 1 Calmodulin binding domain V_ATPase_I PF01496.14 EXF81232.1 - 0.0054 14.6 1.3 0.0063 14.4 0.9 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family PspA_IM30 PF04012.7 EXF81232.1 - 0.4 9.9 15.0 0.95 8.7 10.4 1.5 1 1 0 1 1 1 0 PspA/IM30 family ISG65-75 PF11727.3 EXF81232.1 - 3.1 6.7 6.9 0.73 8.8 2.3 1.6 1 1 1 2 2 2 0 Invariant surface glycoprotein OmpH PF03938.9 EXF81232.1 - 3.4 7.5 12.3 5.1 7.0 8.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PP2C PF00481.16 EXF81233.1 - 2.1e-64 217.3 0.3 9.4e-53 179.2 0.1 3.0 1 1 1 2 2 2 2 Protein phosphatase 2C Zn_clus PF00172.13 EXF81234.1 - 2.4e-07 30.5 12.1 3.9e-07 29.8 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain YEATS PF03366.11 EXF81235.1 - 2.9e-23 81.3 0.0 5.6e-23 80.4 0.0 1.5 1 0 0 1 1 1 1 YEATS family MgtE_N PF03448.12 EXF81235.1 - 0.031 14.5 0.1 0.056 13.7 0.1 1.3 1 0 0 1 1 1 0 MgtE intracellular N domain Ran_BP1 PF00638.13 EXF81236.1 - 1.2e-49 167.4 1.4 1.9e-49 166.7 1.0 1.3 1 0 0 1 1 1 1 RanBP1 domain WH1 PF00568.18 EXF81236.1 - 0.0012 18.5 0.2 0.0043 16.7 0.1 1.8 1 1 0 1 1 1 1 WH1 domain Phosducin PF02114.11 EXF81238.1 - 4.1e-09 35.5 0.1 6e-08 31.7 0.1 2.2 1 1 0 1 1 1 1 Phosducin WD40 PF00400.27 EXF81240.1 - 1.6e-48 160.8 21.1 9.1e-10 38.0 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EXF81240.1 - 8.9e-05 22.2 0.0 0.1 12.2 0.0 2.8 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Cluap1 PF10234.4 EXF81240.1 - 0.13 11.4 1.0 0.19 10.9 0.7 1.1 1 0 0 1 1 1 0 Clusterin-associated protein-1 CwfJ_C_1 PF04677.10 EXF81241.1 - 9.7e-24 83.3 0.0 1.7e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EXF81241.1 - 1.5e-21 76.6 0.7 5.7e-21 74.8 0.7 1.8 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 DRIM PF07539.7 EXF81242.1 - 1.2e-40 138.2 0.1 1e-39 135.1 0.0 2.8 2 0 0 2 2 2 1 Down-regulated in metastasis HEAT PF02985.17 EXF81242.1 - 0.00057 19.7 8.4 12 6.3 0.1 8.9 8 0 0 8 8 8 1 HEAT repeat zf-DNL PF05180.7 EXF81243.1 - 3.5e-28 97.1 0.3 4.8e-28 96.6 0.2 1.2 1 0 0 1 1 1 1 DNL zinc finger zf-CSL PF05207.8 EXF81243.1 - 0.042 13.3 0.3 0.069 12.6 0.2 1.3 1 0 0 1 1 1 0 CSL zinc finger DUF4591 PF15261.1 EXF81243.1 - 0.13 12.5 1.3 0.19 11.9 0.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4591) Cullin PF00888.17 EXF81244.1 - 4.1e-132 441.6 5.1 6e-132 441.1 3.5 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EXF81244.1 - 1.8e-27 94.9 1.1 5.9e-27 93.2 0.8 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain Abhydrolase_3 PF07859.8 EXF81245.1 - 9.3e-31 107.0 0.0 3e-30 105.3 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 EXF81245.1 - 1.1e-08 34.2 0.0 5.7e-08 31.9 0.0 1.8 2 0 0 2 2 2 1 Carboxylesterase family AXE1 PF05448.7 EXF81245.1 - 0.00014 20.4 0.0 0.00043 18.8 0.0 1.7 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EXF81245.1 - 0.0031 16.7 0.0 0.0057 15.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EXF81245.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF81245.1 - 0.056 13.3 0.0 0.091 12.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.15 EXF81245.1 - 0.065 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain BTB PF00651.26 EXF81246.1 - 6.3e-06 26.1 0.1 0.00039 20.3 0.0 2.2 2 0 0 2 2 2 2 BTB/POZ domain dCMP_cyt_deam_1 PF00383.17 EXF81247.1 - 5e-07 29.3 0.5 5e-07 29.3 0.3 1.6 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region Ribosomal_S13_N PF08069.7 EXF81247.1 - 0.12 12.2 0.0 19 5.1 0.0 2.5 2 0 0 2 2 2 0 Ribosomal S13/S15 N-terminal domain BTB PF00651.26 EXF81248.1 - 6.6e-09 35.7 0.0 7.6e-07 29.1 0.0 2.9 3 1 0 3 3 3 1 BTB/POZ domain THAP PF05485.7 EXF81248.1 - 0.019 15.1 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 THAP domain Peptidase_M3 PF01432.15 EXF81249.1 - 1.1e-157 525.7 0.0 1.6e-157 525.2 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M91 PF14891.1 EXF81249.1 - 0.014 15.4 0.0 0.042 13.8 0.0 1.7 1 0 0 1 1 1 0 Effector protein EF-hand_7 PF13499.1 EXF81250.1 - 5.1e-15 55.3 0.2 5e-10 39.3 0.1 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EXF81250.1 - 6.8e-12 44.2 0.2 0.001 18.7 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_9 PF14658.1 EXF81250.1 - 2.4e-11 43.3 0.0 5.7e-06 26.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EXF81250.1 - 4.2e-10 38.1 0.2 0.013 14.8 0.0 4.1 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 EXF81250.1 - 8.6e-08 31.6 0.7 0.00038 20.0 0.1 3.5 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.1 EXF81250.1 - 0.033 13.5 1.2 2.3 7.6 0.7 3.2 3 0 0 3 3 3 0 EF hand UPF0154 PF03672.8 EXF81250.1 - 0.1 12.2 0.0 0.35 10.4 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Methyltransf_11 PF08241.7 EXF81251.1 - 4.4e-20 71.9 0.0 7.5e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF81251.1 - 4.7e-13 49.6 0.0 8.7e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF81251.1 - 1.8e-10 40.8 0.0 3.1e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF81251.1 - 1.4e-09 37.7 0.0 2e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF81251.1 - 6e-09 36.1 0.0 1.1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF81251.1 - 9.6e-09 35.6 0.0 1.6e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF81251.1 - 1.6e-05 24.1 0.0 2.3e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EXF81251.1 - 5.6e-05 22.5 0.0 0.00011 21.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EXF81251.1 - 0.00028 20.8 0.1 0.0011 19.0 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain DREV PF05219.7 EXF81251.1 - 0.0023 16.8 0.0 0.0033 16.3 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase RrnaAD PF00398.15 EXF81251.1 - 0.013 14.5 0.0 0.018 14.0 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase NodS PF05401.6 EXF81251.1 - 0.032 13.6 0.0 0.045 13.1 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) tRNA_U5-meth_tr PF05958.6 EXF81251.1 - 0.091 11.4 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase CoA_binding_2 PF13380.1 EXF81252.1 - 7.2e-27 93.8 0.0 9.5e-27 93.4 0.0 1.1 1 0 0 1 1 1 1 CoA binding domain CoA_binding PF02629.14 EXF81252.1 - 0.011 16.2 0.0 0.016 15.7 0.0 1.2 1 0 0 1 1 1 0 CoA binding domain Grp1_Fun34_YaaH PF01184.14 EXF81253.1 - 3.3e-25 88.6 22.3 4.3e-25 88.2 15.4 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family ELF PF03317.8 EXF81253.1 - 2.5 7.3 3.9 3.7 6.7 2.7 1.2 1 0 0 1 1 1 0 ELF protein DUF373 PF04123.8 EXF81253.1 - 7.2 5.5 8.7 12 4.8 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF373) BTB PF00651.26 EXF81254.1 - 2.1e-05 24.4 0.0 0.00084 19.3 0.0 2.3 2 0 0 2 2 2 2 BTB/POZ domain Cutinase PF01083.17 EXF81255.1 - 8.7e-35 120.0 0.2 1.1e-34 119.7 0.2 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EXF81255.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.4 1 0 0 1 1 1 0 PE-PPE domain DUF3089 PF11288.3 EXF81255.1 - 0.042 12.9 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_2 PF02230.11 EXF81255.1 - 0.065 12.6 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EXF81255.1 - 0.088 12.5 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family VirJ PF06057.6 EXF81255.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_6 PF12697.2 EXF81255.1 - 0.11 12.3 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family BIR PF00653.16 EXF81258.1 - 1.9e-41 140.3 6.6 5.8e-20 71.4 0.0 2.9 3 0 0 3 3 3 2 Inhibitor of Apoptosis domain HRXXH PF13933.1 EXF81259.1 - 1.3e-107 358.8 0.0 1.7e-107 358.4 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Sporozoite_P67 PF05642.6 EXF81259.1 - 0.13 10.0 0.0 0.16 9.7 0.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen HCV_NS5a_1a PF08300.8 EXF81259.1 - 0.14 12.1 0.6 1.3 9.0 0.2 2.4 2 0 0 2 2 2 0 Hepatitis C virus non-structural 5a zinc finger domain Glyco_transf_28 PF03033.15 EXF81260.1 - 5.5e-23 81.2 0.0 1.6e-22 79.7 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_tran_28_C PF04101.11 EXF81260.1 - 0.0029 17.2 0.0 0.0051 16.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.13 EXF81260.1 - 0.0035 15.9 0.0 0.0065 15.0 0.0 1.3 1 1 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase LRR_4 PF12799.2 EXF81261.1 - 0.0041 16.7 0.2 2.8 7.6 0.0 4.1 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) Lipase_GDSL_2 PF13472.1 EXF81262.1 - 1e-17 64.8 0.2 3.1e-17 63.2 0.1 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EXF81262.1 - 3.2e-06 27.1 2.8 1.1e-05 25.4 2.0 2.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase GCP5-Mod21 PF14609.1 EXF81262.1 - 0.27 9.3 0.0 0.39 8.7 0.0 1.1 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 zf-C2H2_2 PF12756.2 EXF81265.1 - 4.7e-26 90.8 6.9 2.6e-25 88.4 1.2 2.4 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EXF81265.1 - 1.8 8.8 9.1 5 7.3 0.0 3.5 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EXF81265.1 - 2.4 8.6 11.5 7.5 7.1 0.9 3.6 3 0 0 3 3 3 0 Zinc finger, C2H2 type tRNA-synt_2b PF00587.20 EXF81266.1 - 6.7e-21 74.6 0.0 1.1e-20 73.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) ProRS-C_1 PF09180.6 EXF81266.1 - 8.3e-19 67.2 0.2 1.7e-18 66.2 0.1 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 EXF81266.1 - 1.9e-17 62.9 0.0 4.5e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain Cpn60_TCP1 PF00118.19 EXF81267.1 - 2.3e-145 484.9 11.7 2.6e-145 484.7 8.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Acetyltransf_7 PF13508.1 EXF81268.1 - 2.2e-06 27.7 0.0 9.3e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EXF81268.1 - 0.0003 20.7 0.8 0.013 15.5 0.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EXF81268.1 - 0.028 14.2 0.1 0.16 11.8 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Ank_2 PF12796.2 EXF81269.1 - 3.1e-43 145.9 2.7 2.4e-14 53.4 0.3 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EXF81269.1 - 1.8e-38 130.2 1.1 6e-11 42.5 0.0 5.9 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 EXF81269.1 - 3.8e-37 124.2 22.3 3.3e-06 26.6 0.2 7.8 7 1 0 7 7 7 7 Ankyrin repeat Ank_3 PF13606.1 EXF81269.1 - 7.8e-28 93.7 4.1 0.00073 19.5 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 EXF81269.1 - 2.7e-20 71.9 16.9 0.00079 19.5 0.2 6.8 2 2 5 7 7 7 7 Ankyrin repeats (many copies) TAXi_C PF14541.1 EXF81269.1 - 0.071 12.6 0.0 7.4 6.0 0.0 2.4 1 1 2 3 3 3 0 Xylanase inhibitor C-terminal SnoaL_2 PF12680.2 EXF81269.1 - 0.25 11.7 1.3 24 5.3 0.1 2.6 2 1 0 2 2 2 0 SnoaL-like domain HTH_32 PF13565.1 EXF81270.1 - 0.046 14.5 2.9 0.058 14.1 0.1 1.9 1 1 1 2 2 2 0 Homeodomain-like domain HTH_29 PF13551.1 EXF81270.1 - 0.072 13.2 0.5 0.12 12.5 0.1 1.4 1 1 1 2 2 2 0 Winged helix-turn helix Hox9_act PF04617.8 EXF81270.1 - 1.1 9.3 4.3 1.2 9.2 3.0 1.0 1 0 0 1 1 1 0 Hox9 activation region GRP PF07172.6 EXF81270.1 - 2.3 8.7 7.5 2.9 8.4 5.1 1.3 1 1 0 1 1 1 0 Glycine rich protein family WD40 PF00400.27 EXF81271.1 - 2.5e-31 106.3 18.0 1.9e-10 40.1 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat HET PF06985.6 EXF81272.1 - 1.2e-31 109.7 0.0 2.2e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF501 PF04417.7 EXF81273.1 - 0.057 13.2 0.1 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF501) Menin PF05053.8 EXF81273.1 - 1.2 7.2 5.8 1.8 6.6 4.0 1.2 1 0 0 1 1 1 0 Menin UCR_TM PF02921.9 EXF81274.1 - 3.9e-18 65.4 1.0 3.9e-18 65.4 0.7 2.1 2 0 0 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region Rieske PF00355.21 EXF81274.1 - 5.1e-17 61.2 0.0 8.2e-17 60.5 0.0 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain MMS1_N PF10433.4 EXF81275.1 - 1.6e-86 290.4 0.0 3e-86 289.5 0.0 1.4 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EXF81275.1 - 3.8e-64 216.8 0.0 1.2e-62 211.8 0.0 2.3 2 0 0 2 2 2 2 CPSF A subunit region Acetyltransf_1 PF00583.19 EXF81276.1 - 1.2e-08 34.8 0.0 2.1e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EXF81276.1 - 0.00016 21.3 0.0 0.00033 20.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EXF81276.1 - 0.0008 19.5 0.0 0.0012 18.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EXF81276.1 - 0.002 18.2 0.0 0.0045 17.0 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EXF81276.1 - 0.027 14.3 0.1 0.25 11.2 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain HsbA PF12296.3 EXF81277.1 - 6.6e-14 51.8 3.7 1e-13 51.1 2.6 1.3 1 0 0 1 1 1 1 Hydrophobic surface binding protein A p450 PF00067.17 EXF81278.1 - 6.4e-53 179.8 0.0 9.6e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Polyketide_cyc2 PF10604.4 EXF81279.1 - 0.00045 20.3 0.0 0.00052 20.1 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport SET PF00856.23 EXF81280.1 - 4.1e-12 46.6 0.1 1.7e-11 44.6 0.0 2.0 1 1 0 1 1 1 1 SET domain Fungal_trans PF04082.13 EXF81283.1 - 5.2e-17 61.5 0.1 1.1e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF81283.1 - 1.9e-07 30.8 5.8 3.1e-07 30.1 4.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 EXF81284.1 - 2.4e-62 211.0 0.0 4e-62 210.2 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 AA_permease_2 PF13520.1 EXF81285.1 - 1.2e-56 192.0 47.8 1.6e-56 191.7 33.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF81285.1 - 3.5e-22 78.3 41.3 4.6e-22 78.0 28.7 1.0 1 0 0 1 1 1 1 Amino acid permease Baculo_helicase PF04735.7 EXF81285.1 - 0.17 9.2 0.6 0.23 8.7 0.4 1.0 1 0 0 1 1 1 0 Baculovirus DNA helicase UNC-50 PF05216.8 EXF81285.1 - 0.68 9.0 9.6 0.67 9.1 1.4 2.8 2 0 0 2 2 2 0 UNC-50 family HgmA PF04209.8 EXF81286.1 - 3.5e-183 608.8 0.0 3.9e-183 608.6 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAA_hydrolase PF01557.13 EXF81287.1 - 8.1e-51 172.5 0.0 1.1e-50 172.1 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EXF81287.1 - 9.5e-26 89.8 0.0 3.1e-25 88.2 0.0 1.8 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal Dabb PF07876.7 EXF81288.1 - 6.6e-15 55.3 0.0 7.9e-15 55.0 0.0 1.1 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain DUF4123 PF13503.1 EXF81288.1 - 0.15 12.0 0.0 0.17 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4123) HET PF06985.6 EXF81291.1 - 2.7e-37 128.0 0.2 8e-37 126.4 0.2 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CMAS PF02353.15 EXF81292.1 - 5.3e-61 206.0 0.2 6.5e-61 205.7 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EXF81292.1 - 2.1e-10 40.5 0.0 3.3e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF81292.1 - 5.5e-05 23.5 0.0 9.2e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF81292.1 - 0.0013 18.7 0.0 0.023 14.7 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EXF81292.1 - 0.0015 17.9 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.8 EXF81292.1 - 0.015 14.6 0.0 0.027 13.7 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.14 EXF81292.1 - 0.021 14.3 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EXF81292.1 - 0.027 15.0 0.1 0.081 13.5 0.1 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EXF81292.1 - 0.042 13.4 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TMEM154 PF15102.1 EXF81293.1 - 0.058 13.0 0.3 0.058 13.0 0.2 2.6 3 1 0 3 3 3 0 TMEM154 protein family Adeno_E3_CR2 PF02439.10 EXF81293.1 - 0.16 11.5 1.5 0.36 10.4 1.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Apc13p PF05839.6 EXF81294.1 - 3.2e-31 107.1 0.1 3.7e-31 106.9 0.1 1.1 1 0 0 1 1 1 1 Apc13p protein TRAPP PF04051.11 EXF81295.1 - 1.8e-38 131.4 0.0 2.1e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component CRAL_TRIO PF00650.15 EXF81296.1 - 2.6e-40 137.5 0.0 3.7e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EXF81296.1 - 1.5e-10 41.0 0.8 3.3e-10 39.9 0.3 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EXF81296.1 - 0.00024 21.0 0.0 0.00033 20.5 0.0 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF3328 PF11807.3 EXF81298.1 - 8.8e-27 94.1 1.5 1.2e-26 93.7 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) NlpE PF04170.7 EXF81300.1 - 0.0057 17.0 0.0 0.44 10.9 0.0 3.2 2 0 0 2 2 2 1 NlpE N-terminal domain S19 PF06756.6 EXF81301.1 - 0.079 12.8 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Chorion protein S19 C-terminal SKG6 PF08693.5 EXF81302.1 - 0.0022 17.2 0.3 0.0044 16.2 0.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain HET PF06985.6 EXF81303.1 - 1.2e-26 93.5 0.1 2e-26 92.7 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3885 PF13021.1 EXF81303.1 - 0.17 11.6 1.1 0.37 10.5 0.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3885) Lipase_GDSL PF00657.17 EXF81304.1 - 1.4e-15 57.7 0.0 1.8e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EXF81304.1 - 1.8e-15 57.5 0.0 2.1e-15 57.2 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 EXF81304.1 - 0.016 14.9 0.0 0.023 14.4 0.0 1.1 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Cellulase PF00150.13 EXF81305.1 - 8.6e-20 71.0 0.5 1.1e-19 70.7 0.3 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EXF81305.1 - 4.9e-07 28.9 0.0 1.3e-06 27.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_42 PF02449.10 EXF81305.1 - 8.4e-05 21.8 0.1 0.00021 20.5 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase Cellulase-like PF12876.2 EXF81305.1 - 0.001 19.4 0.0 0.0022 18.3 0.0 1.6 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_10 PF00331.15 EXF81305.1 - 0.035 13.1 0.3 0.064 12.2 0.2 1.5 1 1 0 1 1 1 0 Glycosyl hydrolase family 10 DUF4038 PF13204.1 EXF81305.1 - 0.039 13.2 2.0 0.061 12.6 1.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4038) CAF-1_p150 PF11600.3 EXF81306.1 - 0.0074 15.6 35.0 0.0074 15.6 24.2 3.4 3 1 1 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Grp1_Fun34_YaaH PF01184.14 EXF81307.1 - 2.7e-23 82.3 6.7 3.4e-23 82.0 4.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3953 PF13129.1 EXF81307.1 - 4.6 6.9 6.3 0.51 10.0 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) Ammonium_transp PF00909.16 EXF81308.1 - 1.3e-98 330.1 19.3 1.5e-98 329.8 13.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF3445 PF11927.3 EXF81309.1 - 2.4e-71 240.0 0.0 3.1e-71 239.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Fungal_trans_2 PF11951.3 EXF81310.1 - 8.7e-25 87.1 2.3 1.4e-18 66.6 1.1 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF81310.1 - 4.5e-08 32.8 7.2 6.9e-08 32.2 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EutQ PF06249.7 EXF81311.1 - 1.3e-12 47.5 0.0 1.7e-12 47.1 0.0 1.0 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ Cupin_3 PF05899.7 EXF81311.1 - 6.9e-10 38.1 0.0 1.5e-09 37.0 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF861) Cupin_2 PF07883.6 EXF81311.1 - 5.9e-05 22.4 0.0 8.4e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.2 EXF81311.1 - 0.0074 15.9 0.0 0.009 15.6 0.0 1.1 1 0 0 1 1 1 1 Cupin KduI PF04962.7 EXF81311.1 - 0.038 13.0 0.0 0.041 12.9 0.0 1.1 1 0 0 1 1 1 0 KduI/IolB family Cupin_1 PF00190.17 EXF81311.1 - 0.11 11.9 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Cupin DUF3445 PF11927.3 EXF81312.1 - 2e-78 263.2 0.0 2.6e-78 262.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) DOPA_dioxygen PF08883.6 EXF81313.1 - 5.1e-25 87.5 0.0 9.1e-25 86.7 0.0 1.4 1 0 0 1 1 1 1 Dopa 4,5-dioxygenase family DUF3328 PF11807.3 EXF81313.1 - 1.1e-19 70.9 0.3 1.7e-19 70.4 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) TAP35_44 PF07265.6 EXF81314.1 - 0.0058 16.3 1.4 12 5.6 0.2 4.1 1 1 4 5 5 5 5 Tapetum specific protein TAP35/TAP44 DinB_2 PF12867.2 EXF81315.1 - 0.00012 22.4 0.3 0.00019 21.7 0.2 1.4 1 0 0 1 1 1 1 DinB superfamily HET PF06985.6 EXF81316.1 - 1.3e-19 70.7 8.0 9.2e-17 61.5 0.8 3.1 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) DUF2541 PF10807.3 EXF81316.1 - 0.02 14.6 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2541) dCMP_cyt_deam_1 PF00383.17 EXF81317.1 - 1.2e-08 34.4 0.1 2.6e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region GST_N_3 PF13417.1 EXF81318.1 - 4.7e-17 61.9 0.0 8.8e-17 61.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EXF81318.1 - 5.2e-14 52.0 0.0 9.8e-14 51.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EXF81318.1 - 8.6e-10 38.6 0.0 2e-09 37.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EXF81318.1 - 0.00079 19.3 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin GST_C PF00043.20 EXF81318.1 - 0.009 15.9 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF2192 PF09958.4 EXF81318.1 - 0.08 12.1 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2192) TPP_enzyme_N PF02776.13 EXF81319.1 - 1.6e-45 154.6 2.2 3.2e-45 153.7 0.5 2.0 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EXF81319.1 - 5.4e-41 139.7 0.2 2.8e-39 134.1 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EXF81319.1 - 1.5e-21 76.6 0.0 4.4e-21 75.0 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Peptidase_M55 PF04951.8 EXF81319.1 - 0.11 11.7 0.1 0.2 10.8 0.1 1.4 1 0 0 1 1 1 0 D-aminopeptidase AAL_decarboxy PF03306.8 EXF81320.1 - 8e-71 237.5 0.1 9e-71 237.4 0.1 1.0 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase TPP_enzyme_N PF02776.13 EXF81322.1 - 7e-34 116.7 0.6 1.1e-33 116.0 0.4 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EXF81322.1 - 1.3e-19 70.3 0.0 1.9e-17 63.2 0.0 2.5 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EXF81322.1 - 1.7e-18 66.7 0.0 4.7e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain NUDIX PF00293.23 EXF81323.1 - 1.3e-08 34.5 0.0 2.7e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Zn_clus PF00172.13 EXF81323.1 - 4.1e-06 26.5 8.9 8.3e-06 25.6 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF81323.1 - 4.6e-06 25.4 1.6 4.6e-06 25.4 1.1 1.4 2 0 0 2 2 2 1 Fungal specific transcription factor domain FAD_binding_4 PF01565.18 EXF81324.1 - 6.4e-18 64.5 1.7 1.1e-17 63.7 1.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF81324.1 - 5.8e-08 32.5 0.2 1.3e-07 31.3 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like p450 PF00067.17 EXF81325.1 - 2.4e-54 184.6 0.0 2.9e-54 184.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pectate_lyase_3 PF12708.2 EXF81326.1 - 1.6e-81 273.7 10.8 6e-63 212.9 0.0 3.6 3 1 0 4 4 4 2 Pectate lyase superfamily protein LysM PF01476.15 EXF81326.1 - 5.5e-09 35.7 0.0 4.2e-05 23.3 0.0 3.2 3 0 0 3 3 3 2 LysM domain End_N_terminal PF12218.3 EXF81326.1 - 3.3e-06 26.4 3.7 0.032 13.6 0.2 2.7 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Glyco_hydro_18 PF00704.23 EXF81327.1 - 5.4e-75 252.9 0.7 5.4e-75 252.9 0.5 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 Chitin_bind_1 PF00187.14 EXF81327.1 - 6.9e-08 32.3 6.5 6.9e-08 32.3 4.5 6.3 8 0 0 8 8 8 2 Chitin recognition protein FAD_binding_3 PF01494.14 EXF81329.1 - 2e-32 112.6 0.2 3.7e-32 111.7 0.2 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF81329.1 - 1.2e-07 30.9 3.5 0.00079 18.4 0.7 2.6 2 1 0 2 2 2 2 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EXF81329.1 - 4.9e-07 29.1 0.0 0.01 14.9 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EXF81329.1 - 1e-06 28.6 0.5 1.2e-05 25.1 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EXF81329.1 - 5e-05 23.6 0.7 0.00095 19.5 0.3 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF81329.1 - 0.0001 21.4 0.1 0.00017 20.7 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EXF81329.1 - 0.00036 20.4 0.1 0.0006 19.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF81329.1 - 0.00036 19.4 0.3 0.00076 18.4 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EXF81329.1 - 0.00042 18.8 0.3 0.0012 17.4 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EXF81329.1 - 0.0011 19.0 0.3 0.0022 18.0 0.2 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EXF81329.1 - 0.0018 17.0 0.7 0.0042 15.7 0.1 1.8 2 0 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.2 EXF81329.1 - 0.0021 17.2 0.4 0.0021 17.2 0.3 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF81329.1 - 0.0023 16.9 0.3 0.68 8.7 0.1 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EXF81329.1 - 0.0067 16.0 0.2 0.018 14.5 0.1 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 EXF81329.1 - 0.017 13.9 1.9 0.048 12.5 1.2 1.9 2 1 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EXF81329.1 - 0.046 13.4 2.3 1.3 8.7 0.2 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding TrkA_N PF02254.13 EXF81329.1 - 0.049 13.6 0.1 0.12 12.3 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain Spherulin4 PF12138.3 EXF81330.1 - 9.6e-35 120.2 1.8 1.3e-34 119.7 1.2 1.2 1 0 0 1 1 1 1 Spherulation-specific family 4 Acetyltransf_1 PF00583.19 EXF81331.1 - 2.2e-06 27.6 0.0 5.6e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EXF81331.1 - 1.9e-05 24.7 0.0 0.00054 20.0 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EXF81331.1 - 2.9e-05 24.1 0.1 4.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EXF81331.1 - 0.0023 17.7 0.0 0.015 15.1 0.0 2.1 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Ldr_toxin PF13940.1 EXF81333.1 - 0.25 11.1 1.4 27 4.6 0.2 2.6 2 0 0 2 2 2 0 Toxin Ldr, type I toxin-antitoxin system SGL PF08450.7 EXF81334.1 - 3.6e-08 33.0 0.2 2.5e-07 30.3 0.1 2.0 1 1 1 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region PQQ_3 PF13570.1 EXF81334.1 - 5.5 7.4 6.9 36 4.8 1.5 4.1 3 1 0 3 3 3 0 PQQ-like domain PEP_mutase PF13714.1 EXF81335.1 - 2.5e-57 193.8 0.5 2.8e-57 193.6 0.4 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase FAD_binding_4 PF01565.18 EXF81336.1 - 2.6e-18 65.8 0.2 4.3e-18 65.1 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF81336.1 - 1.3e-13 50.5 0.0 3e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Sugar_tr PF00083.19 EXF81338.1 - 2.9e-41 141.5 9.7 3.4e-41 141.2 6.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EXF81338.1 - 3.5e-05 22.3 5.6 3.5e-05 22.3 3.9 1.6 2 0 0 2 2 2 1 MFS/sugar transport protein DUF4535 PF15054.1 EXF81338.1 - 0.16 11.4 0.4 0.48 9.8 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4535) Methyltransf_23 PF13489.1 EXF81339.1 - 1.5e-19 70.3 0.0 2.2e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF81339.1 - 1e-10 41.3 0.0 1.7e-09 37.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF81339.1 - 7.5e-09 35.9 0.1 5.7e-08 33.1 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF81339.1 - 6.4e-08 33.1 0.1 1e-06 29.2 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF81339.1 - 1.2e-07 32.1 0.0 2.2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF81339.1 - 1.3e-05 25.4 0.0 3.6e-05 24.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF81339.1 - 0.0014 17.8 0.0 0.082 12.0 0.0 2.8 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EXF81339.1 - 0.012 15.5 0.0 0.018 15.0 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 EXF81339.1 - 0.019 14.3 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain CopK PF11525.3 EXF81339.1 - 0.037 13.6 0.0 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 Copper resistance protein K Methyltransf_16 PF10294.4 EXF81339.1 - 0.051 13.0 0.0 0.13 11.7 0.0 1.7 1 1 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.13 EXF81339.1 - 0.066 12.4 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_26 PF13659.1 EXF81339.1 - 0.085 12.8 0.0 0.19 11.7 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain CMD PF02627.15 EXF81342.1 - 0.0014 18.4 0.0 0.0043 16.8 0.0 1.8 2 0 0 2 2 2 1 Carboxymuconolactone decarboxylase family Glyco_hydro_2_C PF02836.12 EXF81343.1 - 2.8e-85 285.8 0.0 4.6e-85 285.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2_N PF02837.13 EXF81343.1 - 1.7e-38 131.7 0.0 3e-38 131.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EXF81343.1 - 4.3e-14 52.8 0.5 4.8e-13 49.5 0.2 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 DUF4434 PF14488.1 EXF81343.1 - 0.0011 18.7 0.0 0.007 16.1 0.0 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4434) Cellulase PF00150.13 EXF81343.1 - 0.017 14.3 0.0 0.11 11.6 0.0 2.1 1 1 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Cellulase-like PF12876.2 EXF81343.1 - 0.018 15.4 0.0 0.047 14.1 0.0 1.8 1 0 0 1 1 1 0 Sugar-binding cellulase-like p450 PF00067.17 EXF81344.1 - 9.2e-44 149.7 0.0 2.4e-29 102.2 0.0 2.7 2 1 0 2 2 2 2 Cytochrome P450 MCR_beta PF02241.13 EXF81344.1 - 0.013 14.6 0.1 0.051 12.7 0.0 1.9 2 0 0 2 2 2 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain CorA PF01544.13 EXF81345.1 - 7e-05 22.0 3.6 0.00022 20.3 2.5 1.9 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3169 PF11368.3 EXF81345.1 - 0.047 12.8 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Plasmodium_Vir PF05795.6 EXF81345.1 - 0.059 12.5 0.0 0.084 12.0 0.0 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF996 PF06195.8 EXF81345.1 - 0.062 13.3 0.9 0.11 12.5 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF996) Pkinase PF00069.20 EXF81346.1 - 2e-14 53.3 0.0 4.5e-14 52.2 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain NB-ARC PF00931.17 EXF81346.1 - 9.8e-13 47.5 0.0 1.7e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_12 PF13424.1 EXF81346.1 - 3.9e-05 23.4 8.2 0.85 9.6 0.3 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat IstB_IS21 PF01695.12 EXF81346.1 - 8.9e-05 21.9 0.0 0.00024 20.5 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Apc3 PF12895.2 EXF81346.1 - 0.00019 21.5 1.7 0.055 13.6 0.4 2.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 AAA_16 PF13191.1 EXF81346.1 - 0.0008 19.4 0.1 0.011 15.7 0.1 2.7 1 1 0 1 1 1 1 AAA ATPase domain Pkinase_Tyr PF07714.12 EXF81346.1 - 0.00089 18.4 0.0 0.14 11.2 0.0 2.4 2 0 0 2 2 2 1 Protein tyrosine kinase AAA_22 PF13401.1 EXF81346.1 - 0.014 15.5 0.0 0.045 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain TPR_2 PF07719.12 EXF81346.1 - 0.028 14.3 9.6 0.41 10.6 0.4 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EXF81346.1 - 0.029 14.6 11.4 0.22 11.8 0.2 4.2 4 1 1 5 5 4 0 Tetratricopeptide repeat Ras PF00071.17 EXF81346.1 - 0.073 12.4 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Ras family TPR_6 PF13174.1 EXF81346.1 - 0.086 13.3 2.6 16 6.2 0.5 3.7 2 0 0 2 2 2 0 Tetratricopeptide repeat ArsA_ATPase PF02374.10 EXF81346.1 - 0.12 11.3 0.1 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase TPR_14 PF13428.1 EXF81346.1 - 0.31 11.7 19.5 0.82 10.4 0.6 6.8 6 1 1 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.1 EXF81346.1 - 0.39 10.6 4.1 0.86 9.5 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat KaiC PF06745.8 EXF81346.1 - 0.44 9.6 0.1 0.72 8.9 0.0 1.2 1 0 0 1 1 1 0 KaiC TPR_10 PF13374.1 EXF81346.1 - 0.92 9.5 10.2 2.5 8.1 0.2 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EXF81346.1 - 7.4 7.3 29.5 0.14 12.6 0.8 7.4 8 0 0 8 8 5 0 Tetratricopeptide repeat PIF1 PF05970.9 EXF81348.1 - 3.6e-39 134.7 2.4 5.6e-27 94.6 0.0 3.6 2 1 1 3 3 3 3 PIF1-like helicase AAA_30 PF13604.1 EXF81348.1 - 1.4e-18 67.1 0.0 7.3e-15 55.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_19 PF13245.1 EXF81348.1 - 1.6e-08 34.2 0.5 3.4e-08 33.1 0.3 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EXF81348.1 - 3.3e-06 26.8 0.0 6.8e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 EXF81348.1 - 4.8e-06 26.2 0.6 0.11 11.9 0.2 3.1 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase Herpes_Helicase PF02689.9 EXF81348.1 - 7.7e-06 23.9 0.2 0.00032 18.6 0.0 2.2 2 0 0 2 2 2 1 Helicase UvrD_C_2 PF13538.1 EXF81348.1 - 0.00011 22.3 0.4 0.0016 18.5 0.0 3.0 4 0 0 4 4 3 1 UvrD-like helicase C-terminal domain Cauli_VI PF01693.11 EXF81348.1 - 0.00013 21.9 2.3 0.00028 20.8 0.4 2.5 2 0 0 2 2 2 1 Caulimovirus viroplasmin AAA_29 PF13555.1 EXF81348.1 - 0.00049 19.5 0.1 0.001 18.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RNA_helicase PF00910.17 EXF81348.1 - 0.00053 20.1 0.1 0.013 15.6 0.1 2.6 1 1 0 1 1 1 1 RNA helicase AAA_22 PF13401.1 EXF81348.1 - 0.00094 19.3 0.0 0.0022 18.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EXF81348.1 - 0.001 18.2 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EXF81348.1 - 0.0011 18.9 0.0 0.0025 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 EXF81348.1 - 0.0035 16.7 0.7 2.3 7.5 0.0 2.4 1 1 1 2 2 2 2 IstB-like ATP binding protein ABC_tran PF00005.22 EXF81348.1 - 0.0051 17.0 0.5 0.016 15.4 0.0 2.1 2 0 0 2 2 1 1 ABC transporter Helicase_RecD PF05127.9 EXF81348.1 - 0.021 14.4 0.2 0.11 12.1 0.1 2.3 2 1 0 2 2 2 0 Helicase AAA PF00004.24 EXF81348.1 - 0.022 14.9 0.0 0.044 13.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EXF81348.1 - 0.024 14.5 0.0 0.082 12.8 0.0 1.9 1 1 0 1 1 1 0 AAA domain DUF815 PF05673.8 EXF81348.1 - 0.058 12.3 0.1 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Rad17 PF03215.10 EXF81348.1 - 0.07 11.7 0.0 0.11 11.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein DUF258 PF03193.11 EXF81348.1 - 0.092 11.9 0.0 0.17 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NTPase_1 PF03266.10 EXF81348.1 - 0.094 12.4 0.4 6.4 6.4 0.1 2.4 2 0 0 2 2 2 0 NTPase Sigma54_activ_2 PF14532.1 EXF81348.1 - 0.11 12.5 0.0 1.8 8.5 0.0 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.17 EXF81348.1 - 0.13 11.1 0.1 0.22 10.3 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain ATP-synt_ab PF00006.20 EXF81348.1 - 0.15 11.5 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_11 PF13086.1 EXF81348.1 - 0.21 11.1 5.9 2.9 7.4 0.0 3.6 2 1 1 3 3 3 0 AAA domain FAD_binding_4 PF01565.18 EXF81350.1 - 2.1e-26 92.0 6.0 7.1e-26 90.3 4.0 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EXF81350.1 - 9.6e-12 44.6 0.1 1.9e-11 43.6 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Oest_recep PF02159.10 EXF81351.1 - 0.05 13.7 0.5 0.05 13.7 0.4 2.2 2 0 0 2 2 2 0 Oestrogen receptor bZIP_1 PF00170.16 EXF81351.1 - 0.16 11.9 4.9 0.22 11.4 1.7 2.3 1 1 1 2 2 2 0 bZIP transcription factor bZIP_2 PF07716.10 EXF81351.1 - 0.28 11.0 6.0 0.8 9.5 2.4 2.3 1 1 1 2 2 2 0 Basic region leucine zipper Pex14_N PF04695.8 EXF81351.1 - 0.69 9.9 3.9 5.4 7.0 0.0 2.6 2 1 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CFEM PF05730.6 EXF81352.1 - 9.9e-07 28.4 7.8 1.9e-06 27.6 5.4 1.4 1 0 0 1 1 1 1 CFEM domain NPCC PF08058.6 EXF81352.1 - 1.1 9.0 6.6 0.6 9.9 0.1 2.9 2 1 0 2 2 2 0 Nuclear pore complex component TFR_dimer PF04253.10 EXF81353.1 - 1.1e-17 63.7 0.0 1.8e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EXF81353.1 - 1.5e-16 60.6 0.0 3.3e-16 59.5 0.0 1.6 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EXF81353.1 - 9.8e-05 21.9 0.3 0.0019 17.8 0.0 2.3 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 EXF81353.1 - 0.041 13.3 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Peptidase_M13_N PF05649.8 EXF81354.1 - 1.8e-93 313.7 0.0 3e-93 312.9 0.0 1.4 2 0 0 2 2 2 1 Peptidase family M13 Peptidase_M13 PF01431.16 EXF81354.1 - 2e-57 193.7 0.3 1.3e-56 191.0 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M13 SLAC1 PF03595.12 EXF81355.1 - 5.1e-85 285.0 37.3 5.8e-85 284.8 25.8 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel HET PF06985.6 EXF81356.1 - 1.4e-35 122.4 0.2 2.5e-35 121.6 0.2 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ABC_sub_bind PF04392.7 EXF81356.1 - 0.21 10.5 0.0 0.31 9.9 0.0 1.2 1 0 0 1 1 1 0 ABC transporter substrate binding protein CTP_transf_2 PF01467.21 EXF81357.1 - 3.6e-05 23.8 0.1 0.0002 21.4 0.0 2.2 2 1 0 2 2 2 1 Cytidylyltransferase FAD_syn PF06574.7 EXF81357.1 - 0.087 12.4 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 FAD synthetase Peripla_BP_6 PF13458.1 EXF81357.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Periplasmic binding protein Phosphonate-bd PF12974.2 EXF81358.1 - 0.00014 21.3 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.6 EXF81358.1 - 0.00045 19.8 0.0 0.00075 19.1 0.0 1.5 1 1 0 1 1 1 1 NMT1/THI5 like SBP_bac_3 PF00497.15 EXF81358.1 - 0.00063 19.0 0.0 0.0045 16.2 0.0 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 IpaD PF06511.6 EXF81358.1 - 0.15 11.0 0.2 0.23 10.3 0.2 1.2 1 0 0 1 1 1 0 Invasion plasmid antigen IpaD GCD14 PF08704.5 EXF81359.1 - 1.7e-61 207.9 0.0 5.2e-60 202.9 0.0 2.3 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_18 PF12847.2 EXF81359.1 - 0.034 14.7 0.0 0.54 10.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_26 PF13659.1 EXF81359.1 - 0.083 12.9 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain tRNA-synt_1e PF01406.14 EXF81360.1 - 1.2e-111 372.6 0.1 1.8e-111 372.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EXF81360.1 - 8.7e-07 27.9 0.6 0.034 12.7 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.6 EXF81360.1 - 0.002 18.3 0.0 0.002 18.3 0.0 2.4 2 0 0 2 2 2 1 DALR domain DUF3759 PF12585.3 EXF81361.1 - 2.5e-41 139.4 7.4 3.2e-41 139.1 5.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3759) MFS_1 PF07690.11 EXF81363.1 - 3.3e-29 101.6 30.5 2.3e-19 69.3 13.6 2.9 1 1 1 3 3 3 3 Major Facilitator Superfamily PUCC PF03209.10 EXF81363.1 - 0.0018 17.0 3.6 0.0018 17.0 2.5 2.6 2 1 0 2 2 2 1 PUCC protein ATG22 PF11700.3 EXF81363.1 - 0.006 15.1 13.6 0.029 12.8 9.4 2.3 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like MerC PF03203.9 EXF81364.1 - 8.6 6.7 11.9 0.91 9.9 1.7 3.1 2 1 1 3 3 3 0 MerC mercury resistance protein GMC_oxred_N PF00732.14 EXF81365.1 - 1.5e-53 181.9 0.0 2.2e-53 181.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EXF81365.1 - 4.3e-06 25.9 0.3 2.2e-05 23.5 0.2 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein GMC_oxred_C PF05199.8 EXF81365.1 - 6.7e-06 26.4 0.0 1e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EXF81365.1 - 5.3e-05 22.2 0.0 0.029 13.2 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF81365.1 - 0.0068 16.4 0.0 0.022 14.8 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF81365.1 - 0.015 15.1 0.0 0.072 12.9 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF81365.1 - 0.035 14.1 0.0 1.3 9.0 0.0 2.5 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF81365.1 - 0.043 12.6 0.0 5 5.8 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_binding_9 PF13454.1 EXF81365.1 - 0.12 12.1 0.0 0.27 11.0 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding DAO PF01266.19 EXF81366.1 - 2.4e-41 141.8 0.0 4.3e-41 141.0 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amidohydro_2 PF04909.9 EXF81366.1 - 2.8e-27 95.9 0.4 4.4e-27 95.3 0.2 1.3 1 0 0 1 1 1 1 Amidohydrolase NAD_binding_9 PF13454.1 EXF81366.1 - 3.6e-07 30.0 0.1 0.031 14.0 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EXF81366.1 - 2.3e-06 27.6 0.9 0.00031 20.6 0.7 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF81366.1 - 0.00013 20.9 0.1 0.15 10.9 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EXF81366.1 - 0.0019 18.3 0.2 0.16 12.0 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF81366.1 - 0.0025 16.7 0.7 0.0041 16.0 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 EXF81366.1 - 0.022 13.3 0.3 0.92 8.0 0.0 2.4 3 0 0 3 3 3 0 Tryptophan halogenase NAD_binding_8 PF13450.1 EXF81366.1 - 0.028 14.4 0.1 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Cupin_2 PF07883.6 EXF81367.1 - 2.8e-15 55.5 0.1 5e-15 54.7 0.1 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EXF81367.1 - 1.3e-08 34.5 0.3 2.2e-08 33.8 0.0 1.4 2 0 0 2 2 2 1 AraC-like ligand binding domain MannoseP_isomer PF01050.13 EXF81367.1 - 0.0011 18.6 0.0 0.0013 18.3 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase Cupin_1 PF00190.17 EXF81367.1 - 0.0027 17.1 0.0 0.0031 16.9 0.0 1.3 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EXF81367.1 - 0.013 14.8 0.0 0.033 13.5 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF861) Cupin_6 PF12852.2 EXF81367.1 - 0.034 13.7 0.1 0.13 11.9 0.0 1.7 1 1 1 2 2 2 0 Cupin CENP-C_C PF11699.3 EXF81367.1 - 0.055 13.4 0.0 0.08 12.9 0.0 1.2 1 0 0 1 1 1 0 Mif2/CENP-C like Cupin_7 PF12973.2 EXF81367.1 - 0.059 13.2 0.0 0.1 12.4 0.0 1.7 1 1 0 1 1 1 0 ChrR Cupin-like domain Glyco_hydro_43 PF04616.9 EXF81368.1 - 2.5e-32 112.1 0.8 3.3e-32 111.7 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Zn_clus PF00172.13 EXF81369.1 - 2.3e-10 40.2 12.9 4e-10 39.4 9.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF81369.1 - 0.00037 19.4 0.0 0.00068 18.5 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EXF81370.1 - 7.3e-30 103.7 0.0 1e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain CN_hydrolase PF00795.17 EXF81371.1 - 3.7e-30 104.6 0.0 4.8e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Dehydratase_hem PF13816.1 EXF81372.1 - 1.4e-107 359.3 0.0 1.6e-107 359.1 0.0 1.0 1 0 0 1 1 1 1 Haem-containing dehydratase DUF4188 PF13826.1 EXF81372.1 - 1.6e-07 31.3 0.0 0.0023 18.0 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4188) ABM PF03992.11 EXF81372.1 - 0.11 12.5 2.2 0.28 11.2 0.3 2.4 3 0 0 3 3 3 0 Antibiotic biosynthesis monooxygenase Carb_anhydrase PF00194.16 EXF81374.1 - 9.6e-19 67.3 0.1 2.5e-18 65.9 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase MGC-24 PF05283.6 EXF81375.1 - 0.00014 21.7 5.3 0.00014 21.7 3.7 2.5 2 1 0 2 2 2 1 Multi-glycosylated core protein 24 (MGC-24) DUF4229 PF14012.1 EXF81375.1 - 0.021 14.7 0.0 0.047 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) TMEM154 PF15102.1 EXF81375.1 - 0.021 14.5 0.0 0.021 14.5 0.0 2.0 2 0 0 2 2 2 0 TMEM154 protein family DUF3611 PF12263.3 EXF81375.1 - 0.038 13.3 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) Syndecan PF01034.15 EXF81375.1 - 0.039 13.6 0.3 0.1 12.2 0.2 1.7 1 0 0 1 1 1 0 Syndecan domain Gly-zipper_OmpA PF13436.1 EXF81375.1 - 2 8.0 12.9 3.3 7.4 1.0 3.1 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain CHRD PF07452.7 EXF81379.1 - 0.022 15.3 0.0 0.06 13.9 0.0 1.8 2 1 0 2 2 2 0 CHRD domain Peptidase_S9 PF00326.16 EXF81382.1 - 5.9e-41 140.0 0.0 8.9e-41 139.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EXF81382.1 - 5.6e-13 48.8 0.3 1.2e-12 47.7 0.2 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF81382.1 - 3.4e-11 43.4 0.2 7.4e-11 42.3 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EXF81382.1 - 4.4e-08 32.8 0.1 0.0015 18.0 0.0 2.3 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 EXF81382.1 - 3.1e-05 23.3 0.1 0.00017 20.9 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family LIP PF03583.9 EXF81382.1 - 8.8e-05 21.8 0.0 0.00024 20.3 0.0 1.7 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_3 PF07859.8 EXF81382.1 - 0.0013 18.3 0.1 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold PQQ PF01011.16 EXF81382.1 - 0.0025 17.2 0.0 3.3 7.4 0.0 3.2 2 0 0 2 2 2 2 PQQ enzyme repeat Abhydrolase_1 PF00561.15 EXF81382.1 - 0.016 14.7 0.1 0.24 10.9 0.1 2.3 1 1 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EXF81382.1 - 0.027 13.8 0.0 0.05 13.0 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Fungal_trans PF04082.13 EXF81385.1 - 2.6e-50 170.7 0.1 3.8e-50 170.1 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EXF81385.1 - 2.2e-07 30.7 6.4 0.0058 16.9 1.1 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF81385.1 - 3.6e-06 26.9 10.2 0.00065 19.8 1.3 3.6 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EXF81385.1 - 2.7 8.4 9.3 0.19 12.0 0.2 3.1 3 0 0 3 3 3 0 Zinc-finger double domain Ribosomal_S8 PF00410.14 EXF81386.1 - 4e-10 39.6 0.0 7.6e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S8 Cupin_1 PF00190.17 EXF81387.1 - 5.7e-12 45.2 0.0 8.6e-12 44.6 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.6 EXF81387.1 - 0.0018 17.7 0.0 0.0065 15.9 0.0 1.9 1 1 0 1 1 1 1 Cupin domain Ank_2 PF12796.2 EXF81388.1 - 1.2e-26 92.8 0.1 2.5e-16 59.7 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EXF81388.1 - 7e-17 60.3 0.1 1.2e-08 34.3 0.1 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EXF81388.1 - 1e-14 54.2 0.4 6.1e-07 29.4 0.1 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF81388.1 - 1.7e-14 52.4 0.1 1.7e-06 27.6 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EXF81388.1 - 4.3e-14 52.5 0.0 2.8e-07 30.8 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Phe_tRNA-synt_N PF02912.13 EXF81388.1 - 0.083 12.6 0.0 0.25 11.1 0.0 1.7 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain TP6A_N PF04406.9 EXF81389.1 - 3e-16 58.8 0.0 6.1e-16 57.8 0.0 1.5 1 0 0 1 1 1 1 Type IIB DNA topoisomerase Prenyltrans PF00432.16 EXF81390.1 - 3e-20 71.4 6.2 1.3e-09 37.4 0.3 5.9 6 0 0 6 6 6 2 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EXF81390.1 - 3.2e-16 59.7 3.5 2.3e-07 31.2 0.1 5.2 4 2 1 5 5 5 3 Prenyltransferase-like Prenyltrans_1 PF13243.1 EXF81390.1 - 4.4e-15 55.6 0.2 1.6e-08 34.5 0.1 5.5 3 2 1 5 5 5 2 Prenyltransferase-like Phage_F PF02305.12 EXF81390.1 - 0.025 13.1 0.1 0.038 12.5 0.1 1.1 1 0 0 1 1 1 0 Capsid protein (F protein) Pec_lyase PF09492.5 EXF81390.1 - 0.029 13.5 0.5 1.7 7.7 0.0 3.3 4 0 0 4 4 4 0 Pectic acid lyase Chromadorea_ALT PF05535.7 EXF81390.1 - 0.034 14.2 0.1 0.12 12.4 0.1 1.9 1 0 0 1 1 1 0 Chromadorea ALT protein SGS PF05002.10 EXF81391.1 - 2e-27 94.7 1.5 5.3e-27 93.3 1.0 1.8 1 0 0 1 1 1 1 SGS domain CS PF04969.11 EXF81391.1 - 9.1e-13 48.5 0.0 2e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 CS domain TPR_11 PF13414.1 EXF81391.1 - 4e-08 32.7 0.3 4.7e-06 26.1 0.0 2.4 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EXF81391.1 - 2.6e-05 23.7 0.1 0.67 10.0 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EXF81391.1 - 9.9e-05 22.9 3.4 0.01 16.4 3.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.23 EXF81391.1 - 0.017 14.7 0.0 0.48 10.1 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2057 PF09829.4 EXF81391.1 - 0.1 12.2 1.9 0.25 10.9 1.3 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) TPR_14 PF13428.1 EXF81391.1 - 0.11 13.1 1.1 11 6.9 0.2 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TauD PF02668.11 EXF81392.1 - 2e-58 198.0 0.1 3.2e-58 197.4 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EXF81392.1 - 0.0061 15.5 0.0 0.015 14.2 0.0 1.5 2 0 0 2 2 2 1 CsiD 2OG-FeII_Oxy_3 PF13640.1 EXF81392.1 - 0.0083 16.6 0.4 0.031 14.8 0.0 2.2 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily DUF971 PF06155.7 EXF81392.1 - 0.039 14.3 0.0 0.15 12.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF971) DUF4193 PF13834.1 EXF81392.1 - 0.15 12.2 0.2 0.26 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4193) Lipase_GDSL_2 PF13472.1 EXF81393.1 - 3.4e-16 59.9 0.6 4.7e-16 59.4 0.4 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EXF81393.1 - 1.7e-12 47.7 2.0 2.3e-12 47.2 1.4 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase tRNA_int_endo PF01974.12 EXF81394.1 - 1.4e-18 66.4 0.0 3e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EXF81394.1 - 0.00043 19.7 0.0 0.14 11.7 0.0 2.5 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain Nramp PF01566.13 EXF81394.1 - 0.0091 14.8 0.0 0.013 14.3 0.0 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Glyco_transf_21 PF13506.1 EXF81395.1 - 6.7e-11 41.7 0.0 0.0004 19.7 0.0 3.3 3 0 0 3 3 3 3 Glycosyl transferase family 21 Glyco_tranf_2_3 PF13641.1 EXF81395.1 - 1.5e-10 41.2 0.0 3.8e-10 39.9 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EXF81395.1 - 0.00036 20.2 0.0 0.007 16.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Tannase PF07519.6 EXF81396.1 - 1.6e-117 393.1 0.1 2e-117 392.8 0.1 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.15 EXF81396.1 - 0.0027 17.2 0.0 0.0066 16.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans_2 PF11951.3 EXF81397.1 - 5.3e-08 31.8 0.0 5.8e-08 31.7 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain NUDIX PF00293.23 EXF81398.1 - 0.0056 16.3 0.0 0.0097 15.5 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Big_5 PF13205.1 EXF81398.1 - 0.14 12.7 1.4 4 8.0 0.3 2.3 2 0 0 2 2 2 0 Bacterial Ig-like domain MFS_1 PF07690.11 EXF81399.1 - 6e-06 25.1 20.6 1.3e-05 24.1 7.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF202 PF02656.10 EXF81399.1 - 1.4 9.2 9.1 1.2e+03 -0.3 6.3 3.2 1 1 0 1 1 1 0 Domain of unknown function (DUF202) Acyl-CoA_dh_2 PF08028.6 EXF81400.1 - 2.9e-18 66.4 0.1 2.9e-18 66.4 0.1 1.4 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EXF81400.1 - 0.00032 21.2 0.0 0.00057 20.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EXF81400.1 - 0.00075 19.6 0.9 0.0098 16.0 0.0 2.5 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain DUF2190 PF09956.4 EXF81400.1 - 0.022 14.5 0.1 0.085 12.6 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2190) Grp1_Fun34_YaaH PF01184.14 EXF81401.1 - 3.9e-37 127.6 15.5 4.8e-37 127.2 10.7 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF3784 PF12650.2 EXF81401.1 - 0.82 9.6 9.0 0.13 12.2 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) Bac_luciferase PF00296.15 EXF81402.1 - 1.1e-60 205.4 0.0 1.3e-60 205.0 0.0 1.1 1 0 0 1 1 1 1 Luciferase-like monooxygenase p450 PF00067.17 EXF81403.1 - 1.6e-57 195.0 0.0 2.5e-57 194.4 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Cys_rich_FGFR PF00839.12 EXF81403.1 - 0.095 12.6 0.3 0.22 11.4 0.2 1.6 1 0 0 1 1 1 0 Cysteine rich repeat Mito_carr PF00153.22 EXF81404.1 - 1.7e-19 69.3 6.0 8.7e-08 31.7 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Glyco_hydro_61 PF03443.9 EXF81406.1 - 3.1e-40 138.3 0.0 5e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 zf-C2H2_4 PF13894.1 EXF81407.1 - 0.0014 18.8 0.9 0.0028 17.8 0.6 1.5 1 0 0 1 1 1 1 C2H2-type zinc finger Oxidored_FMN PF00724.15 EXF81407.1 - 0.083 11.8 0.0 0.12 11.3 0.0 1.2 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family Ndc1_Nup PF09531.5 EXF81407.1 - 0.12 10.7 0.3 0.14 10.5 0.2 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIF_alpha PF05793.7 EXF81407.1 - 1.9 6.7 9.5 2.4 6.4 6.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Herpes_LMP1 PF05297.6 EXF81407.1 - 2.2 7.1 7.7 2.6 6.8 5.4 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) Tyrosinase PF00264.15 EXF81410.1 - 4.7e-29 102.1 2.4 9.4e-29 101.1 1.6 1.5 1 1 0 1 1 1 1 Common central domain of tyrosinase DUF2029 PF09594.5 EXF81410.1 - 0.13 11.7 0.6 0.2 11.1 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) MS_channel PF00924.13 EXF81411.1 - 7.3e-21 74.4 0.4 1.2e-20 73.7 0.3 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_7 PF13499.1 EXF81411.1 - 0.00031 20.8 0.9 0.001 19.1 0.4 2.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EXF81411.1 - 0.011 15.5 0.6 1.4 8.9 0.1 2.8 1 1 1 2 2 2 0 EF-hand domain EF-hand_1 PF00036.27 EXF81411.1 - 0.015 14.5 0.7 0.042 13.1 0.2 2.1 2 0 0 2 2 2 0 EF hand DUF373 PF04123.8 EXF81411.1 - 3.1 6.7 7.2 3.6 6.4 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Glyco_hydro_2_N PF02837.13 EXF81412.1 - 3e-07 30.1 0.0 5.8e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain ADH_zinc_N PF00107.21 EXF81413.1 - 1.3e-13 50.6 0.3 2.6e-13 49.6 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF81413.1 - 1.7e-06 27.7 0.0 3.5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EXF81413.1 - 0.00054 20.8 0.0 0.0012 19.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_31 PF01055.21 EXF81414.1 - 6.4e-153 509.7 3.0 9.2e-153 509.1 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EXF81414.1 - 4.1e-23 81.0 0.1 1.1e-22 79.6 0.1 1.8 1 0 0 1 1 1 1 Galactose mutarotase-like COesterase PF00135.23 EXF81415.1 - 8.7e-99 331.6 0.0 1e-98 331.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF81415.1 - 1.2e-06 28.2 0.1 1.5e-05 24.6 0.1 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold NDK PF00334.14 EXF81416.1 - 1e-53 180.7 0.0 1.4e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase FLILHELTA PF10306.4 EXF81417.1 - 3.2e-26 91.1 0.0 6.5e-26 90.1 0.0 1.5 1 0 0 1 1 1 1 Hypothetical protein FLILHELTA DUF1279 PF06916.8 EXF81417.1 - 0.0094 16.2 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) Glyco_hydro_17 PF00332.13 EXF81419.1 - 4.6e-07 29.1 0.3 6.1e-07 28.7 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 17 DUF992 PF06186.6 EXF81419.1 - 0.0099 15.2 0.1 0.025 13.9 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF992) Sugar_tr PF00083.19 EXF81420.1 - 2.3e-16 59.4 0.6 4.8e-10 38.5 0.0 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter TPR_12 PF13424.1 EXF81421.1 - 1.7e-10 40.7 5.3 0.005 16.7 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EXF81421.1 - 6.2e-07 28.8 8.3 0.1 12.5 0.0 6.1 6 0 0 6 6 5 2 Tetratricopeptide repeat AAA_16 PF13191.1 EXF81421.1 - 6.6e-07 29.5 0.3 1.1e-05 25.5 0.0 3.0 3 0 0 3 3 3 1 AAA ATPase domain TPR_1 PF00515.23 EXF81421.1 - 6.8e-07 28.6 0.7 0.57 9.8 0.2 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EXF81421.1 - 1.1e-06 27.9 0.4 0.26 11.1 0.1 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EXF81421.1 - 2.2e-06 27.2 8.6 0.0057 16.2 0.1 4.8 3 1 2 5 5 5 3 TPR repeat TPR_14 PF13428.1 EXF81421.1 - 4.4e-06 26.8 1.3 1.2 10.0 0.0 5.7 4 1 1 5 5 4 2 Tetratricopeptide repeat NACHT PF05729.7 EXF81421.1 - 0.00024 20.8 0.0 0.00069 19.3 0.0 1.9 1 0 0 1 1 1 1 NACHT domain TPR_16 PF13432.1 EXF81421.1 - 0.00037 21.0 3.9 1.2 9.8 0.7 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat AAA_22 PF13401.1 EXF81421.1 - 0.00046 20.3 0.4 0.0052 16.9 0.0 2.9 3 0 0 3 3 2 1 AAA domain Arch_ATPase PF01637.13 EXF81421.1 - 0.0038 16.9 0.1 0.0038 16.9 0.1 2.2 2 0 0 2 2 2 1 Archaeal ATPase MobB PF03205.9 EXF81421.1 - 0.0051 16.5 0.0 0.025 14.2 0.0 2.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B TPR_17 PF13431.1 EXF81421.1 - 0.019 15.1 1.0 1.2 9.5 0.3 4.2 4 0 0 4 4 3 0 Tetratricopeptide repeat AAA_25 PF13481.1 EXF81421.1 - 0.033 13.6 0.0 0.15 11.4 0.0 2.2 2 0 0 2 2 1 0 AAA domain MMR_HSR1 PF01926.18 EXF81421.1 - 0.033 14.1 1.0 0.15 12.0 0.0 2.7 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_29 PF13555.1 EXF81421.1 - 0.053 13.0 0.0 0.17 11.4 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Cytomega_gL PF01801.11 EXF81421.1 - 0.063 12.7 2.8 0.11 12.0 0.5 2.3 2 0 0 2 2 2 0 Cytomegalovirus glycoprotein L Dynamin_N PF00350.18 EXF81421.1 - 0.069 12.9 0.1 0.26 11.0 0.0 2.1 1 0 0 1 1 1 0 Dynamin family AAA PF00004.24 EXF81421.1 - 0.13 12.4 3.2 1.7 8.8 0.1 3.7 4 1 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) TPR_7 PF13176.1 EXF81421.1 - 0.86 9.5 5.9 3 7.8 0.0 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EXF81421.1 - 6.8 7.3 8.3 1.1e+02 3.5 0.2 6.0 6 0 0 6 6 4 0 Tetratricopeptide repeat Pyrophosphatase PF00719.14 EXF81422.1 - 1.4e-37 128.5 0.1 2.6e-37 127.6 0.0 1.5 2 0 0 2 2 2 1 Inorganic pyrophosphatase RTA1 PF04479.8 EXF81424.1 - 3.6e-37 128.0 6.9 5.9e-37 127.3 4.8 1.3 1 0 0 1 1 1 1 RTA1 like protein DUF2721 PF11026.3 EXF81424.1 - 0.066 12.8 0.5 0.066 12.8 0.4 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2721) DUF373 PF04123.8 EXF81424.1 - 2.3 7.1 8.9 1.1 8.2 1.4 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF373) MFS_1 PF07690.11 EXF81425.1 - 6.7e-44 150.0 53.2 7.9e-40 136.6 19.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF81425.1 - 1.9e-13 49.8 21.6 4.3e-13 48.6 15.0 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter Fungal_trans PF04082.13 EXF81426.1 - 6.4e-28 97.3 0.0 1.1e-27 96.6 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 EXF81427.1 - 5.3e-09 35.6 0.0 9.9e-08 31.4 0.0 2.6 2 1 0 2 2 2 1 FAD binding domain Pyr_redox PF00070.22 EXF81427.1 - 0.00016 22.0 1.1 0.0016 18.7 0.0 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF81427.1 - 0.033 13.0 0.0 2.7 6.7 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EXF81427.1 - 0.058 12.4 0.0 1.2 8.1 0.0 2.1 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Lycopene_cycl PF05834.7 EXF81427.1 - 0.098 11.5 0.1 10 4.9 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Voldacs PF03517.8 EXF81429.1 - 1.8e-24 86.1 0.6 2.6e-24 85.5 0.0 1.6 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling DUF1049 PF06305.6 EXF81430.1 - 0.022 14.2 1.3 0.033 13.6 0.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Melibiase PF02065.13 EXF81431.1 - 1.2e-20 73.6 3.5 7.9e-17 61.0 0.0 3.3 3 1 0 3 3 3 3 Melibiase FAD_binding_4 PF01565.18 EXF81432.1 - 8.5e-22 77.1 2.9 1.4e-21 76.4 2.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF81432.1 - 0.0035 17.2 0.0 0.0069 16.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like DUF1996 PF09362.5 EXF81433.1 - 1.8e-73 247.0 0.0 2.7e-73 246.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) TPR_11 PF13414.1 EXF81434.1 - 8e-10 38.2 0.0 1e-08 34.6 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EXF81434.1 - 0.00012 21.6 0.0 3.1 7.9 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat UBA PF00627.26 EXF81434.1 - 0.00038 20.2 0.3 0.001 18.8 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain TPR_1 PF00515.23 EXF81434.1 - 0.0025 17.3 0.0 0.68 9.6 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat DnaJ PF00226.26 EXF81434.1 - 0.0041 16.8 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain TPR_12 PF13424.1 EXF81434.1 - 0.022 14.6 0.0 0.36 10.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat UQ_con PF00179.21 EXF81435.1 - 1.2e-51 173.8 0.0 1.4e-51 173.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme LSM PF01423.17 EXF81437.1 - 4.4e-15 54.9 0.2 6.1e-15 54.5 0.2 1.2 1 0 0 1 1 1 1 LSM domain DPPIV_N PF00930.16 EXF81438.1 - 2.2e-107 358.7 0.7 3.1e-107 358.2 0.5 1.2 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EXF81438.1 - 4e-37 127.5 0.1 7.2e-37 126.6 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EXF81438.1 - 3.2e-06 26.9 0.0 8e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF81438.1 - 2.9e-05 24.0 0.1 0.00014 21.7 0.1 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Pkinase PF00069.20 EXF81439.1 - 1.3e-15 57.2 0.0 9.3e-14 51.1 0.0 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF81439.1 - 4.8e-08 32.3 0.1 0.0014 17.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Choline_kinase PF01633.15 EXF81439.1 - 3.3e-05 23.5 0.0 6.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EXF81439.1 - 0.00031 20.5 1.8 0.00036 20.3 0.1 1.8 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EXF81439.1 - 0.03 13.4 0.3 0.067 12.2 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1888 PF08985.6 EXF81439.1 - 0.13 11.9 0.0 9.8 5.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1888) Methyltransf_33 PF10017.4 EXF81440.1 - 4.2e-28 97.7 0.0 9e-28 96.7 0.0 1.6 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent FGE-sulfatase PF03781.11 EXF81440.1 - 1.1e-15 57.6 2.0 1.1e-09 38.0 0.0 2.8 2 1 0 2 2 2 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.2 EXF81440.1 - 3.6e-06 27.3 0.9 1.2e-05 25.6 0.6 2.0 1 1 0 1 1 1 1 DinB superfamily Methyltransf_25 PF13649.1 EXF81440.1 - 0.0015 18.8 0.0 0.0031 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain BAF1_ABF1 PF04684.8 EXF81440.1 - 0.76 8.5 4.2 1.2 7.9 2.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Peptidase_S28 PF05577.7 EXF81441.1 - 2e-50 171.6 1.4 1.5e-49 168.8 0.9 1.9 1 1 0 1 1 1 1 Serine carboxypeptidase S28 Gla PF00594.15 EXF81441.1 - 0.11 12.1 0.3 1.4 8.6 0.1 2.5 2 0 0 2 2 2 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Fungal_trans PF04082.13 EXF81442.1 - 1.3e-16 60.2 0.0 2.1e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF81442.1 - 6.5e-08 32.3 7.7 1.2e-07 31.5 5.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SSP160 PF06933.6 EXF81444.1 - 2.8 5.7 10.2 3.6 5.4 7.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ank_2 PF12796.2 EXF81448.1 - 4.4e-52 174.3 6.7 8.9e-14 51.6 0.0 7.1 3 2 2 6 6 6 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EXF81448.1 - 2.6e-39 132.8 4.9 5.4e-08 33.1 0.0 8.9 6 1 2 8 8 8 7 Ankyrin repeats (many copies) Ank PF00023.25 EXF81448.1 - 4.8e-36 120.7 23.5 2.7e-05 23.7 0.1 11.6 12 0 0 12 12 12 8 Ankyrin repeat Ank_3 PF13606.1 EXF81448.1 - 4e-34 113.2 16.2 0.00069 19.6 0.0 11.8 13 0 0 13 13 13 8 Ankyrin repeat Ank_5 PF13857.1 EXF81448.1 - 6.4e-22 77.0 12.4 0.0007 19.7 0.1 9.2 7 3 4 11 11 11 5 Ankyrin repeats (many copies) Clr5 PF14420.1 EXF81448.1 - 3.8e-07 29.8 0.3 8.6e-07 28.7 0.2 1.6 1 0 0 1 1 1 1 Clr5 domain Shigella_OspC PF06128.6 EXF81448.1 - 0.059 12.8 0.0 19 4.6 0.0 3.1 3 0 0 3 3 3 0 Shigella flexneri OspC protein SDA1 PF05285.7 EXF81449.1 - 2.7e-87 293.0 35.6 2.7e-87 293.0 24.7 2.4 3 0 0 3 3 3 2 SDA1 NUC130_3NT PF08158.7 EXF81449.1 - 8e-17 61.2 0.2 1.9e-16 60.0 0.2 1.7 1 0 0 1 1 1 1 NUC130/3NT domain MFS_1 PF07690.11 EXF81451.1 - 3.4e-21 75.3 66.4 1.7e-15 56.6 37.3 4.0 1 1 1 2 2 2 2 Major Facilitator Superfamily PAM2 PF07145.10 EXF81452.1 - 0.15 11.6 0.4 0.15 11.6 0.3 2.7 3 0 0 3 3 3 0 Ataxin-2 C-terminal region AMP-binding PF00501.23 EXF81453.1 - 4.7e-83 278.8 0.0 6.3e-83 278.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EXF81453.1 - 2.9e-06 28.1 0.0 6.9e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF3483 PF11982.3 EXF81454.1 - 0.023 14.0 0.9 0.027 13.7 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3483) LAB_N PF07578.6 EXF81454.1 - 0.062 13.2 0.5 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Lipid A Biosynthesis N-terminal domain MFS_1 PF07690.11 EXF81455.1 - 1.5e-29 102.8 58.9 2.9e-24 85.4 20.4 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF81455.1 - 3.7e-05 22.1 2.2 3.7e-05 22.1 1.5 2.0 1 1 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) p450 PF00067.17 EXF81456.1 - 6.6e-68 229.3 0.0 1.1e-67 228.5 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 Amidase PF01425.16 EXF81457.1 - 5.4e-94 315.5 0.0 6.2e-94 315.3 0.0 1.0 1 0 0 1 1 1 1 Amidase Zn_clus PF00172.13 EXF81458.1 - 2.4e-07 30.5 8.7 4.8e-07 29.5 6.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EXF81459.1 - 2.4e-18 66.0 18.7 1e-14 54.0 3.7 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily Amidase PF01425.16 EXF81460.1 - 6.8e-93 311.9 0.0 8.2e-93 311.6 0.0 1.1 1 0 0 1 1 1 1 Amidase AF0941-like PF14591.1 EXF81460.1 - 0.01 15.8 0.0 0.018 15.0 0.0 1.3 1 0 0 1 1 1 0 AF0941-like Ribosomal_S5_C PF03719.10 EXF81460.1 - 0.17 11.1 0.6 1.1 8.5 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain Amino_oxidase PF01593.19 EXF81461.1 - 4.2e-50 171.1 0.4 7.6e-50 170.2 0.3 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Ribonuc_L-PSP PF01042.16 EXF81461.1 - 1.8e-17 63.2 0.0 3.2e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP NAD_binding_8 PF13450.1 EXF81461.1 - 1.7e-14 53.5 0.1 4.6e-14 52.2 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EXF81461.1 - 5.5e-10 38.6 0.2 1e-09 37.8 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF81461.1 - 1.5e-09 37.2 1.8 9.4e-08 31.3 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF81461.1 - 2.1e-08 33.5 0.4 7.4e-06 25.1 0.2 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EXF81461.1 - 2.9e-07 30.5 0.0 9.8e-06 25.5 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF81461.1 - 8.2e-07 29.2 0.5 5.1e-05 23.4 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF81461.1 - 2.1e-06 26.9 0.2 3.6e-06 26.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EXF81461.1 - 3.3e-06 26.4 0.1 5.6e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EXF81461.1 - 6.8e-06 25.3 1.2 1.1e-05 24.7 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EXF81461.1 - 2.4e-05 23.0 0.5 0.00017 20.1 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein GIDA PF01134.17 EXF81461.1 - 0.0011 17.8 1.4 0.0016 17.3 0.3 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EXF81461.1 - 0.002 18.5 0.2 0.0052 17.1 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EXF81461.1 - 0.0073 15.8 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain RE_SinI PF09570.5 EXF81462.1 - 0.12 11.3 0.1 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 SinI restriction endonuclease Aldolase_II PF00596.16 EXF81463.1 - 1.4e-47 161.7 0.1 1.7e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF3148 PF11347.3 EXF81463.1 - 0.021 14.4 0.0 0.09 12.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3148) Fungal_trans_2 PF11951.3 EXF81464.1 - 1.8e-62 211.1 0.3 2.8e-62 210.5 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EXF81465.1 - 7.3e-20 70.9 13.4 1.2e-19 70.2 9.3 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EXF81465.1 - 0.15 11.8 3.0 1.3 8.8 0.2 3.1 3 0 0 3 3 3 0 MFS_1 like family NAD_binding_2 PF03446.10 EXF81466.1 - 8.4e-31 107.0 0.8 1.3e-30 106.3 0.6 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EXF81466.1 - 1.6e-08 34.6 0.5 4.4e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Peptidase_S8 PF00082.17 EXF81467.1 - 1.2e-38 132.9 6.9 1.6e-38 132.4 4.8 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EXF81467.1 - 5.3e-11 42.9 0.0 9.4e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Alpha-amylase PF00128.19 EXF81468.1 - 2.7e-30 105.8 3.7 7e-30 104.4 2.6 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EXF81468.1 - 8.1e-07 27.2 1.3 0.21 9.3 0.0 3.1 3 0 0 3 3 3 3 Glycosyl hydrolase family 70 Aldedh PF00171.17 EXF81469.1 - 1e-181 604.3 1.2 1.2e-181 604.1 0.8 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EXF81469.1 - 0.0011 17.8 0.0 0.005 15.6 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.6 EXF81469.1 - 0.054 12.7 0.0 1.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Bac_rhamnosid PF05592.6 EXF81470.1 - 8.7e-135 449.8 0.0 1.1e-134 449.4 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 EXF81470.1 - 8.7e-50 168.5 0.0 1.4e-49 167.9 0.0 1.3 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Pab87_oct PF13969.1 EXF81470.1 - 0.016 15.3 0.3 0.23 11.5 0.0 2.8 3 0 0 3 3 3 0 Pab87 octamerisation domain DUF608 PF04685.8 EXF81470.1 - 0.035 12.8 0.2 0.055 12.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF608 Sugar_tr PF00083.19 EXF81471.1 - 2.9e-102 342.5 21.6 3.4e-102 342.3 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF81471.1 - 8.9e-32 110.1 42.4 4.7e-28 97.9 17.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily CoA_binding_3 PF13727.1 EXF81471.1 - 0.018 14.8 1.0 0.08 12.7 0.0 2.4 2 0 0 2 2 2 0 CoA-binding domain adh_short PF00106.20 EXF81472.1 - 4.4e-14 52.7 0.1 6.5e-14 52.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF81472.1 - 2.3e-08 33.9 0.0 4.8e-08 32.8 0.0 1.5 2 0 0 2 2 2 1 KR domain Amidase PF01425.16 EXF81473.1 - 1.9e-33 115.9 0.1 3.5e-33 115.1 0.1 1.3 1 0 0 1 1 1 1 Amidase Cytochrome_C7 PF14522.1 EXF81474.1 - 1.2 8.8 8.7 0.092 12.3 2.4 1.9 2 0 0 2 2 2 0 Cytochrome c7 CBFNT PF08143.6 EXF81475.1 - 0.27 12.3 3.9 0.45 11.6 2.7 1.4 1 0 0 1 1 1 0 CBFNT (NUC161) domain Ribonucleas_3_3 PF14622.1 EXF81476.1 - 4.2e-09 36.4 0.0 5.9e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EXF81476.1 - 2.8e-06 27.7 0.0 1.4e-05 25.4 0.0 1.9 1 1 0 1 1 1 1 Ribonuclease III domain GMC_oxred_N PF00732.14 EXF81477.1 - 9.4e-59 198.9 0.0 1.5e-58 198.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF81477.1 - 3.4e-29 102.0 0.0 7.8e-29 100.8 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EXF81477.1 - 5.6e-06 25.4 0.0 0.00034 19.5 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EXF81477.1 - 0.0001 22.2 0.1 0.00023 21.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF81477.1 - 0.0016 17.4 0.0 0.043 12.7 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF81477.1 - 0.0026 16.7 0.0 0.0038 16.1 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EXF81477.1 - 0.0044 17.1 0.1 5.1 7.1 0.0 2.6 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EXF81477.1 - 0.011 14.7 0.0 0.017 14.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain HI0933_like PF03486.9 EXF81477.1 - 0.053 11.9 0.0 0.078 11.4 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EXF81477.1 - 0.099 11.7 0.0 0.17 10.9 0.0 1.3 1 0 0 1 1 1 0 Thi4 family bZIP_1 PF00170.16 EXF81478.1 - 2.2e-10 40.3 12.8 4.3e-10 39.4 8.9 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EXF81478.1 - 3.9e-05 23.3 11.0 3.9e-05 23.3 7.6 2.4 2 0 0 2 2 2 1 Basic region leucine zipper DUF904 PF06005.7 EXF81478.1 - 0.011 15.9 2.8 0.011 15.9 2.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF904) DivIC PF04977.10 EXF81478.1 - 0.052 13.0 14.3 0.1 12.1 1.7 2.7 2 0 0 2 2 2 0 Septum formation initiator CASP_C PF08172.7 EXF81478.1 - 7.2 5.5 21.2 17 4.3 14.7 1.6 1 0 0 1 1 1 0 CASP C terminal Pyr_redox_3 PF13738.1 EXF81480.1 - 1.7e-21 77.2 0.2 4.4e-21 75.8 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF81480.1 - 1.8e-13 50.2 0.4 4.2e-10 39.4 0.2 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF81480.1 - 3.4e-13 49.9 0.0 4.5e-05 23.4 0.0 3.3 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF81480.1 - 1.3e-08 34.1 6.6 0.00078 18.4 0.0 4.1 4 1 0 4 4 4 3 FAD dependent oxidoreductase K_oxygenase PF13434.1 EXF81480.1 - 1.1e-07 31.0 0.2 0.00017 20.6 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EXF81480.1 - 2.5e-07 29.2 0.1 0.00016 20.0 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like NAD_binding_9 PF13454.1 EXF81480.1 - 3.5e-06 26.8 3.8 0.13 11.9 0.2 3.8 3 1 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox PF00070.22 EXF81480.1 - 2.4e-05 24.6 1.5 0.059 13.7 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF81480.1 - 0.00015 20.7 0.9 0.0012 17.8 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EXF81480.1 - 0.00066 18.8 4.0 0.33 10.0 0.0 2.8 4 0 0 4 4 4 2 Thi4 family FAD_oxidored PF12831.2 EXF81480.1 - 0.0013 17.8 0.6 0.0041 16.2 0.5 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EXF81480.1 - 0.0023 18.1 0.4 0.21 11.8 0.1 3.0 2 1 1 3 3 3 1 Putative NAD(P)-binding GIDA PF01134.17 EXF81480.1 - 0.004 16.0 7.6 0.16 10.8 0.0 3.3 4 0 0 4 4 4 2 Glucose inhibited division protein A HI0933_like PF03486.9 EXF81480.1 - 0.0076 14.7 2.7 1.2 7.4 0.2 3.2 3 0 0 3 3 3 1 HI0933-like protein 2-Hacid_dh_C PF02826.14 EXF81480.1 - 0.0081 15.3 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FAD_binding_3 PF01494.14 EXF81480.1 - 0.0092 15.0 1.0 0.12 11.4 0.0 2.7 3 0 0 3 3 3 1 FAD binding domain Semialdhyde_dh PF01118.19 EXF81480.1 - 0.012 15.9 0.0 0.26 11.5 0.0 2.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EXF81480.1 - 0.02 13.8 0.9 0.25 10.1 0.0 2.8 3 1 0 3 3 3 0 Lycopene cyclase protein Shikimate_DH PF01488.15 EXF81480.1 - 0.021 14.9 0.1 0.9 9.6 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.16 EXF81480.1 - 0.039 13.7 3.5 3.9 7.2 0.0 3.3 4 0 0 4 4 4 0 ThiF family DEAD PF00270.24 EXF81481.1 - 2.8e-18 65.9 0.0 6.4e-18 64.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EXF81481.1 - 2.7e-08 33.8 0.0 1.5e-07 31.4 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EXF81481.1 - 7.1e-08 32.2 0.1 1.7e-07 31.0 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PhoH PF02562.11 EXF81481.1 - 0.018 14.3 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein SicP-binding PF09119.5 EXF81481.1 - 0.053 13.2 0.1 0.18 11.5 0.0 1.9 1 0 0 1 1 1 0 SicP binding MFS_1 PF07690.11 EXF81482.1 - 7.9e-29 100.4 30.8 7.9e-29 100.4 21.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily NmrA PF05368.8 EXF81483.1 - 8e-23 80.8 0.0 3.4e-11 42.8 0.1 2.1 1 1 1 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.1 EXF81483.1 - 5.9e-06 26.4 0.3 1.3e-05 25.3 0.1 1.6 1 1 1 2 2 2 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EXF81483.1 - 0.0048 17.1 0.4 0.0088 16.3 0.1 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DXP_reductoisom PF02670.11 EXF81483.1 - 0.062 13.8 0.7 0.19 12.2 0.1 2.0 2 0 0 2 2 2 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase F420_oxidored PF03807.12 EXF81483.1 - 0.064 13.6 0.2 0.14 12.5 0.2 1.7 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.15 EXF81483.1 - 0.099 12.5 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 EXF81483.1 - 0.1 11.2 0.0 0.15 10.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EXF81483.1 - 0.15 11.6 0.1 0.55 9.8 0.0 1.9 2 0 0 2 2 2 0 KR domain DLH PF01738.13 EXF81484.1 - 1.2e-20 73.7 0.0 1.5e-20 73.4 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EXF81484.1 - 8.1e-08 32.1 0.0 1.1e-07 31.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF81484.1 - 0.046 12.9 0.2 0.4 9.8 0.0 2.0 1 1 1 2 2 2 0 Prolyl oligopeptidase family adh_short PF00106.20 EXF81485.1 - 5.5e-24 84.9 0.1 7.1e-24 84.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF81485.1 - 8.6e-15 55.1 0.1 1.1e-14 54.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF81485.1 - 2.2e-07 30.7 0.1 4.6e-07 29.6 0.1 1.5 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EXF81485.1 - 1.3e-05 25.2 0.6 0.0016 18.4 0.2 2.1 2 0 0 2 2 2 1 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EXF81485.1 - 0.00024 20.8 0.4 0.00052 19.7 0.3 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Shikimate_DH PF01488.15 EXF81485.1 - 0.00038 20.5 0.9 0.00081 19.4 0.2 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EXF81485.1 - 0.00083 19.7 0.8 0.0028 18.0 0.2 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 EXF81485.1 - 0.004 16.1 0.9 0.012 14.5 0.6 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EXF81485.1 - 0.021 14.2 1.1 1.3 8.4 0.1 2.3 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family Dioxygenase_C PF00775.16 EXF81486.1 - 1.3e-43 148.4 0.0 1.5e-43 148.1 0.0 1.0 1 0 0 1 1 1 1 Dioxygenase CarboxypepD_reg PF13620.1 EXF81486.1 - 0.017 15.1 0.0 0.078 13.0 0.0 2.1 1 1 0 1 1 1 0 Carboxypeptidase regulatory-like domain adh_short_C2 PF13561.1 EXF81487.1 - 5.1e-23 82.0 0.0 7e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EXF81487.1 - 6.3e-20 71.7 0.1 6.3e-20 71.7 0.1 1.4 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EXF81487.1 - 2.3e-10 40.4 0.1 2.3e-10 40.4 0.1 1.5 2 0 0 2 2 2 1 KR domain Ank_2 PF12796.2 EXF81488.1 - 5e-14 52.4 1.0 5.3e-06 26.6 0.1 3.8 3 1 2 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EXF81488.1 - 9.5e-12 44.1 1.6 0.00012 21.6 0.1 5.2 5 0 0 5 5 5 2 Ankyrin repeat NACHT PF05729.7 EXF81488.1 - 3.6e-10 39.7 0.1 4.6e-09 36.1 0.0 2.3 2 0 0 2 2 2 1 NACHT domain Ank_4 PF13637.1 EXF81488.1 - 2.1e-06 28.0 1.2 0.02 15.3 0.0 4.3 4 1 1 5 5 4 2 Ankyrin repeats (many copies) AAA_16 PF13191.1 EXF81488.1 - 3.9e-06 26.9 0.0 0.00017 21.6 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain Ank_3 PF13606.1 EXF81488.1 - 0.00019 21.3 4.1 1.2 9.5 0.0 5.8 7 0 0 7 7 6 1 Ankyrin repeat AAA_17 PF13207.1 EXF81488.1 - 0.00057 20.7 0.1 0.11 13.3 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 EXF81488.1 - 0.00088 19.4 0.1 0.064 13.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EXF81488.1 - 0.014 14.3 0.0 0.027 13.4 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.1 EXF81488.1 - 0.016 14.5 0.0 0.18 11.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain Ank_5 PF13857.1 EXF81488.1 - 0.032 14.5 4.5 14 6.1 0.0 4.9 3 2 2 5 5 5 0 Ankyrin repeats (many copies) AAA_19 PF13245.1 EXF81488.1 - 0.032 13.9 0.0 0.094 12.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA PF00004.24 EXF81488.1 - 0.054 13.6 0.0 0.14 12.3 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Fic PF02661.13 EXF81488.1 - 0.12 13.0 0.0 1.2 9.9 0.0 2.4 2 0 0 2 2 2 0 Fic/DOC family RuvB_N PF05496.7 EXF81488.1 - 0.12 11.3 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EXF81488.1 - 0.13 12.0 0.1 0.39 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EXF81488.1 - 0.14 12.4 0.1 0.87 9.8 0.0 2.3 1 1 1 2 2 2 0 AAA domain HeLo PF14479.1 EXF81489.1 - 0.03 14.0 1.6 0.037 13.7 0.2 1.7 2 0 0 2 2 2 0 Prion-inhibition and propagation YihI PF04220.7 EXF81489.1 - 0.05 12.9 1.9 1.8 7.8 0.1 2.2 1 1 1 2 2 2 0 Der GTPase activator (YihI) DAO PF01266.19 EXF81489.1 - 0.058 12.2 0.1 0.1 11.4 0.1 1.6 1 1 0 1 1 1 0 FAD dependent oxidoreductase HMD PF03201.11 EXF81489.1 - 0.084 12.8 0.9 0.22 11.4 0.6 1.8 1 1 0 1 1 1 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase Acyl-CoA_dh_1 PF00441.19 EXF81490.1 - 1e-40 139.2 0.9 2e-40 138.3 0.6 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EXF81490.1 - 8e-31 106.9 0.2 1.6e-30 105.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EXF81490.1 - 5.9e-21 73.7 0.5 1.3e-20 72.6 0.3 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EXF81490.1 - 1.5e-13 51.1 0.1 3.5e-13 49.9 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EXF81490.1 - 0.00026 20.4 0.3 0.0012 18.2 0.2 1.9 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Carboxyl_trans PF01039.17 EXF81491.1 - 2.5e-143 478.0 0.1 3.4e-143 477.5 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain NUDIX PF00293.23 EXF81492.1 - 2e-12 46.8 0.1 1e-11 44.5 0.1 1.8 1 1 0 1 1 1 1 NUDIX domain DLH PF01738.13 EXF81493.1 - 5.9e-18 64.9 0.0 6.7e-18 64.7 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EXF81493.1 - 0.028 14.1 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ank_2 PF12796.2 EXF81494.1 - 2.2e-54 181.7 0.1 2.1e-10 40.7 0.0 7.9 4 3 4 8 8 8 7 Ankyrin repeats (3 copies) Ank PF00023.25 EXF81494.1 - 3.9e-40 133.6 0.7 0.00034 20.2 0.0 13.1 14 0 0 14 14 14 8 Ankyrin repeat Ank_4 PF13637.1 EXF81494.1 - 2.1e-36 123.6 4.5 2.3e-08 34.3 0.0 10.4 6 5 6 12 12 12 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF81494.1 - 2.3e-34 116.6 3.1 2.5e-06 27.5 0.1 8.8 6 3 5 11 11 11 8 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF81494.1 - 3.7e-27 91.6 0.9 0.027 14.6 0.0 12.6 14 0 0 14 14 14 7 Ankyrin repeat AAA_16 PF13191.1 EXF81494.1 - 2e-08 34.4 0.7 1.8e-07 31.3 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EXF81494.1 - 2.4e-06 27.7 3.6 3.8e-05 23.8 0.0 3.2 3 0 0 3 3 3 1 AAA domain NACHT PF05729.7 EXF81494.1 - 8.1e-06 25.5 1.0 2.1e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 NACHT domain PLC-beta_C PF08703.5 EXF81494.1 - 0.22 11.2 6.8 0.057 13.1 1.6 2.4 2 1 0 2 2 2 0 PLC-beta C terminal Ank_2 PF12796.2 EXF81495.1 - 9.1e-24 83.6 0.1 1.4e-13 50.9 0.1 2.2 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EXF81495.1 - 5.9e-22 77.6 0.5 4e-10 39.9 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF81495.1 - 4.7e-19 67.9 1.5 2.8e-08 33.7 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EXF81495.1 - 6e-16 57.3 2.5 0.0025 17.5 0.1 5.3 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 EXF81495.1 - 2.7e-12 45.6 0.1 0.01 16.0 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Raptor_N PF14538.1 EXF81496.1 - 3.5e-66 221.7 0.0 7.7e-66 220.6 0.0 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EXF81496.1 - 2.6e-08 33.4 3.3 1 9.3 0.0 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat HEAT PF02985.17 EXF81496.1 - 0.0016 18.3 3.8 14 6.1 0.0 5.2 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 EXF81496.1 - 0.0026 18.0 0.2 0.17 12.2 0.0 3.2 3 1 1 4 4 4 2 HEAT repeats BBS2_Mid PF14783.1 EXF81496.1 - 0.0095 15.7 0.1 4.9 6.9 0.1 2.6 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Atx10homo_assoc PF09759.4 EXF81496.1 - 0.018 14.8 0.1 0.033 13.9 0.1 1.4 1 0 0 1 1 1 0 Spinocerebellar ataxia type 10 protein domain Kelch_4 PF13418.1 EXF81497.1 - 5.5e-36 122.0 9.6 4.2e-09 36.0 0.5 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EXF81497.1 - 4.5e-31 106.2 12.6 9.7e-09 35.1 0.2 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.1 EXF81497.1 - 1.4e-30 104.6 13.5 1.1e-08 34.8 0.2 6.9 7 0 0 7 7 7 6 Kelch motif Kelch_1 PF01344.20 EXF81497.1 - 4e-30 103.0 7.7 4.4e-12 45.3 0.7 6.6 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.1 EXF81497.1 - 3.9e-27 93.2 8.5 6.7e-11 41.8 0.8 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EXF81497.1 - 1.5e-19 68.8 8.4 6e-07 28.9 0.2 6.6 6 0 0 6 6 6 5 Kelch motif Filament PF00038.16 EXF81497.1 - 0.0011 18.5 29.2 0.0011 18.5 20.2 3.9 2 1 1 4 4 4 1 Intermediate filament protein RAG2 PF03089.9 EXF81497.1 - 0.021 13.5 0.7 1 8.0 0.0 3.4 4 1 0 4 4 4 0 Recombination activating protein 2 GATA PF00320.22 EXF81498.1 - 1.6e-16 59.3 1.9 3.4e-16 58.2 1.3 1.6 1 0 0 1 1 1 1 GATA zinc finger DUF1752 PF08550.5 EXF81498.1 - 1.2e-13 50.3 1.6 2.4e-13 49.4 1.1 1.5 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1752) SMC_N PF02463.14 EXF81499.1 - 2.2e-25 89.1 0.0 5.1e-25 88.0 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EXF81499.1 - 7.3e-13 49.3 58.8 4e-11 43.6 12.9 4.9 2 2 1 3 3 3 1 AAA domain AAA_21 PF13304.1 EXF81499.1 - 8.2e-07 29.2 0.2 0.0014 18.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain CENP-F_leu_zip PF10473.4 EXF81499.1 - 0.0018 18.1 1.1 0.0018 18.1 0.8 5.7 4 2 1 5 5 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EXF81499.1 - 0.0024 17.1 8.9 0.31 10.1 0.0 3.9 3 1 0 4 4 4 2 Reovirus sigma C capsid protein GAS PF13851.1 EXF81499.1 - 0.0024 17.0 6.6 0.0024 17.0 4.6 5.7 2 2 2 5 5 5 1 Growth-arrest specific micro-tubule binding AAA_29 PF13555.1 EXF81499.1 - 0.0068 15.9 0.0 0.014 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EXF81499.1 - 0.017 14.5 0.2 0.081 12.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain NPV_P10 PF05531.7 EXF81499.1 - 0.057 13.6 14.2 1.1 9.5 0.1 6.1 4 2 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Pkinase PF00069.20 EXF81500.1 - 2.9e-71 239.6 0.0 5.2e-71 238.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF81500.1 - 2.5e-33 115.2 0.0 8.4e-33 113.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF81500.1 - 9e-05 21.5 0.0 0.00014 20.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EXF81500.1 - 0.00025 20.8 0.0 0.0029 17.3 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EXF81500.1 - 0.0085 15.6 2.7 0.011 15.2 0.1 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase Kdo PF06293.9 EXF81500.1 - 0.016 14.3 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Malate_synthase PF01274.17 EXF81501.1 - 3.4e-233 774.4 0.0 3.8e-233 774.2 0.0 1.0 1 0 0 1 1 1 1 Malate synthase MFS_1 PF07690.11 EXF81502.1 - 1e-24 86.9 17.1 1e-24 86.9 11.9 1.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Helicase_C PF00271.26 EXF81503.1 - 3.7e-22 77.9 0.2 1.9e-18 66.0 0.0 3.1 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.24 EXF81503.1 - 7.4e-22 77.6 0.1 6.7e-21 74.5 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.5 EXF81503.1 - 1.8e-11 43.7 0.0 4.9e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 RQC domain SNF2_N PF00176.18 EXF81503.1 - 0.00019 20.3 0.0 0.00032 19.6 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HRDC PF00570.18 EXF81503.1 - 0.0028 17.3 0.0 0.0076 15.9 0.0 1.7 1 0 0 1 1 1 1 HRDC domain UPF0242 PF06785.6 EXF81503.1 - 4.1 5.9 10.8 9.1 4.8 7.5 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) KAR9 PF08580.5 EXF81504.1 - 1.3e-139 466.6 1.0 1.3e-139 466.6 0.7 2.2 2 0 0 2 2 2 1 Yeast cortical protein KAR9 Syntaxin-6_N PF09177.6 EXF81504.1 - 0.27 11.6 6.9 0.34 11.3 0.2 4.0 4 1 0 4 4 4 0 Syntaxin 6, N-terminal DUF3782 PF12644.2 EXF81505.1 - 0.1 12.3 0.2 0.23 11.2 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3782) AAA PF00004.24 EXF81506.1 - 1.3e-42 145.1 0.0 2.2e-42 144.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EXF81506.1 - 6e-08 32.8 0.1 4.8e-06 26.6 0.0 2.9 2 1 1 3 3 3 1 AAA ATPase domain AAA_5 PF07728.9 EXF81506.1 - 1.8e-06 27.7 0.1 3.7e-05 23.4 0.0 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EXF81506.1 - 2.2e-06 27.7 0.0 7.6e-06 25.9 0.0 1.9 3 0 0 3 3 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EXF81506.1 - 2.9e-06 27.4 0.0 0.001 19.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EXF81506.1 - 7.3e-06 25.1 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EXF81506.1 - 0.00022 20.2 0.0 0.00058 18.8 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EXF81506.1 - 0.00034 20.3 0.0 0.00075 19.1 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EXF81506.1 - 0.00052 20.8 0.6 0.0023 18.7 0.1 2.3 2 1 0 2 2 2 1 AAA domain DUF4200 PF13863.1 EXF81506.1 - 0.00067 19.6 1.5 0.0017 18.3 1.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4200) AAA_14 PF13173.1 EXF81506.1 - 0.0011 18.8 0.0 0.0027 17.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.8 EXF81506.1 - 0.0017 17.1 0.0 0.0031 16.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EXF81506.1 - 0.0021 17.9 0.0 0.0062 16.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EXF81506.1 - 0.0021 18.3 0.1 0.0082 16.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EXF81506.1 - 0.0022 17.4 0.0 0.0054 16.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EXF81506.1 - 0.003 16.7 0.0 0.0062 15.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.1 EXF81506.1 - 0.0041 16.7 0.3 0.25 10.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EXF81506.1 - 0.005 16.9 0.0 0.0096 16.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase Zeta_toxin PF06414.7 EXF81506.1 - 0.0054 15.8 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin Sigma54_activat PF00158.21 EXF81506.1 - 0.0075 15.7 0.0 0.025 14.0 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 EXF81506.1 - 0.009 15.4 0.1 0.047 13.0 0.1 2.1 1 1 1 2 2 2 1 AAA domain AAA_3 PF07726.6 EXF81506.1 - 0.009 15.6 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EXF81506.1 - 0.02 14.5 0.1 0.04 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EXF81506.1 - 0.023 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EXF81506.1 - 0.024 14.6 0.0 0.064 13.3 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Arch_ATPase PF01637.13 EXF81506.1 - 0.025 14.2 0.0 0.13 11.9 0.0 2.2 1 1 0 1 1 1 0 Archaeal ATPase eIF-1a PF01176.14 EXF81506.1 - 0.025 13.9 0.1 0.05 13.0 0.1 1.5 1 0 0 1 1 1 0 Translation initiation factor 1A / IF-1 ResIII PF04851.10 EXF81506.1 - 0.029 14.2 0.0 0.062 13.1 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit KaiC PF06745.8 EXF81506.1 - 0.031 13.4 0.4 0.11 11.5 0.0 2.1 3 0 0 3 3 3 0 KaiC PhoH PF02562.11 EXF81506.1 - 0.031 13.5 0.0 0.056 12.6 0.0 1.3 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.7 EXF81506.1 - 0.04 13.5 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 EXF81506.1 - 0.045 13.3 0.0 0.099 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EXF81506.1 - 0.076 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EXF81506.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_23 PF13476.1 EXF81506.1 - 0.14 12.5 4.2 2.8 8.2 0.1 2.6 2 1 0 2 2 2 0 AAA domain SIS PF01380.17 EXF81507.1 - 2.9e-54 182.1 0.1 1.1e-29 102.7 0.0 2.3 2 0 0 2 2 2 2 SIS domain GATase_2 PF00310.16 EXF81507.1 - 9.7e-28 96.8 0.0 5.6e-19 68.0 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EXF81507.1 - 1.1e-19 70.7 0.0 2.7e-19 69.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EXF81507.1 - 1e-11 44.6 0.0 2.4e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EXF81507.1 - 9.9e-08 30.9 0.0 1.6e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II PTSIIB_sorb PF03830.10 EXF81507.1 - 0.033 14.0 0.1 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 PTS system sorbose subfamily IIB component SIS_2 PF13580.1 EXF81507.1 - 0.034 13.8 0.0 0.31 10.7 0.0 2.4 2 0 0 2 2 2 0 SIS domain CAP18_C PF12153.3 EXF81507.1 - 0.051 13.2 0.3 0.1 12.2 0.2 1.5 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) Proteasome PF00227.21 EXF81508.1 - 8.6e-28 96.9 0.0 1e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit HMG_box_2 PF09011.5 EXF81509.1 - 2.1e-09 37.6 0.3 2.1e-09 37.6 0.2 3.4 3 1 0 3 3 3 1 HMG-box domain HMG_box PF00505.14 EXF81509.1 - 1.1e-07 31.9 0.6 1.1e-07 31.9 0.4 3.4 3 0 0 3 3 3 2 HMG (high mobility group) box HMG_box_5 PF14887.1 EXF81509.1 - 0.0051 16.5 0.0 0.0051 16.5 0.0 2.7 2 1 0 2 2 2 1 HMG (high mobility group) box 5 DUF3945 PF13101.1 EXF81509.1 - 0.033 13.4 0.3 0.11 11.7 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3945) Rnk_N PF14760.1 EXF81509.1 - 0.1 12.6 0.3 0.31 11.1 0.0 2.0 2 0 0 2 2 2 0 Rnk N-terminus Dicty_REP PF05086.7 EXF81509.1 - 2.7 5.6 4.7 2.9 5.5 3.3 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein 3Beta_HSD PF01073.14 EXF81511.1 - 5.2e-66 222.1 0.0 6.8e-66 221.8 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EXF81511.1 - 1.9e-32 112.6 0.3 3.7e-32 111.6 0.1 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EXF81511.1 - 1.1e-16 60.5 0.3 1.7e-16 59.9 0.2 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EXF81511.1 - 3.4e-15 55.6 0.2 3.3e-12 45.8 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EXF81511.1 - 1.5e-12 47.8 0.2 2.1e-12 47.4 0.2 1.2 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EXF81511.1 - 2.5e-07 29.8 0.0 9e-07 28.0 0.2 1.9 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EXF81511.1 - 5.9e-07 29.5 0.6 1.2e-06 28.5 0.4 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_3 PF03447.11 EXF81511.1 - 0.00063 20.1 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain KR PF08659.5 EXF81511.1 - 0.0008 19.1 1.8 0.004 16.8 1.2 2.0 1 1 0 1 1 1 1 KR domain DapB_N PF01113.15 EXF81511.1 - 0.048 13.5 0.2 0.11 12.4 0.1 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus RhoGAP PF00620.22 EXF81512.1 - 4.2e-36 123.8 0.0 8.9e-36 122.7 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain LIM PF00412.17 EXF81512.1 - 1.7e-31 108.0 40.1 1.8e-11 43.9 3.7 5.0 5 0 0 5 5 5 4 LIM domain dCMP_cyt_deam_1 PF00383.17 EXF81513.1 - 3e-19 68.5 0.0 4.2e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EXF81513.1 - 0.01 15.7 0.9 0.066 13.0 0.6 2.0 1 1 0 1 1 1 0 Bd3614-like deaminase zf-HC5HC2H_2 PF13832.1 EXF81514.1 - 3.3e-20 72.1 0.5 3.3e-20 72.1 0.4 4.4 5 0 0 5 5 5 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EXF81514.1 - 2.5e-17 62.7 1.1 2.5e-17 62.7 0.8 5.0 4 1 0 4 4 4 1 PHD-like zinc-binding domain BAH PF01426.13 EXF81514.1 - 5e-17 61.7 0.0 1.1e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 BAH domain PHD PF00628.24 EXF81514.1 - 7e-11 41.6 55.8 1.4e-06 27.9 6.0 6.3 6 0 0 6 6 6 3 PHD-finger PHD_2 PF13831.1 EXF81514.1 - 7.7e-09 34.7 4.5 7.7e-09 34.7 3.1 5.2 6 0 0 6 6 6 2 PHD-finger Myb_DNA-binding PF00249.26 EXF81514.1 - 0.0029 17.6 0.4 0.009 16.0 0.0 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain C1_1 PF00130.17 EXF81514.1 - 0.0038 16.9 2.9 0.0038 16.9 2.0 6.0 6 1 1 7 7 7 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EXF81514.1 - 3 7.6 45.5 0.033 13.9 1.0 5.1 5 0 0 5 5 5 0 Prokaryotic RING finger family 1 DEAD PF00270.24 EXF81516.1 - 2.5e-10 40.1 0.0 6.9e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF81516.1 - 1.4e-07 31.2 0.0 3.6e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 EXF81516.1 - 2.6e-05 24.2 0.2 0.00017 21.6 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix domain BTB PF00651.26 EXF81517.1 - 0.00012 22.0 0.1 0.00029 20.7 0.0 1.6 2 0 0 2 2 2 1 BTB/POZ domain COesterase PF00135.23 EXF81518.1 - 2e-68 231.4 0.1 4.9e-68 230.1 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF81518.1 - 2.9e-07 30.2 0.0 7.1e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EXF81518.1 - 3.7e-05 23.0 0.0 5.8e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EXF81518.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF81519.1 - 5.5e-12 46.0 0.0 1.8e-11 44.3 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF81519.1 - 7e-10 38.8 0.0 2.2e-09 37.2 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF81519.1 - 1.7e-07 31.1 0.0 1.5e-06 28.0 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.7 EXF81519.1 - 0.0019 16.8 0.0 0.0045 15.6 0.0 1.6 2 0 0 2 2 2 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 EXF81519.1 - 0.0033 16.6 0.0 0.014 14.5 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.15 EXF81519.1 - 0.004 16.5 0.0 0.0075 15.7 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Peptidase_S10 PF00450.17 EXF81519.1 - 0.038 13.1 0.1 3.4 6.7 0.0 2.2 2 0 0 2 2 2 0 Serine carboxypeptidase Hydrolase_4 PF12146.3 EXF81519.1 - 0.1 12.4 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase SNARE_assoc PF09335.6 EXF81521.1 - 1.5e-12 47.7 6.3 1.5e-12 47.7 4.4 2.5 2 1 0 3 3 3 1 SNARE associated Golgi protein DUF1771 PF08590.5 EXF81522.1 - 2.9e-13 49.5 10.9 2.9e-13 49.5 7.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EXF81522.1 - 1.5e-09 37.9 0.0 5e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 Smr domain zf-CCCH PF00642.19 EXF81522.1 - 5.5e-07 29.1 3.5 0.00078 19.0 0.3 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) HBS1_N PF08938.5 EXF81522.1 - 0.007 16.4 0.1 0.019 15.1 0.0 1.8 2 0 0 2 2 2 1 HBS1 N-terminus Cupin_8 PF13621.1 EXF81523.1 - 7.6e-18 64.9 0.1 4.5e-17 62.3 0.1 2.0 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EXF81523.1 - 1.5e-09 38.1 0.1 6.6e-09 36.0 0.0 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.2 EXF81523.1 - 1.4e-05 24.7 0.2 1.4e-05 24.7 0.1 2.3 3 0 0 3 3 3 1 F-box-like F-box PF00646.28 EXF81523.1 - 0.00025 20.6 0.1 0.00069 19.2 0.1 1.8 1 0 0 1 1 1 1 F-box domain DEAD PF00270.24 EXF81524.1 - 3e-44 150.4 2.5 3.8e-44 150.1 1.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF81524.1 - 1.2e-27 95.5 0.3 6.2e-27 93.2 0.1 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EXF81524.1 - 0.00073 19.4 0.1 0.0015 18.3 0.1 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.1 EXF81524.1 - 0.0022 17.5 0.3 0.0062 16.1 0.1 1.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EXF81524.1 - 0.016 14.9 0.1 0.046 13.4 0.0 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_22 PF13401.1 EXF81524.1 - 0.022 14.8 0.2 0.085 12.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.1 EXF81524.1 - 0.023 13.7 0.0 0.05 12.6 0.0 1.5 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit UvrD-helicase PF00580.16 EXF81524.1 - 0.058 12.6 0.4 0.083 12.1 0.2 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain Flavi_DEAD PF07652.9 EXF81524.1 - 0.066 12.9 0.2 0.32 10.7 0.1 2.2 1 1 0 1 1 1 0 Flavivirus DEAD domain tRNA-synt_1b PF00579.20 EXF81524.1 - 0.067 12.3 0.2 0.29 10.2 0.0 2.0 3 0 0 3 3 3 0 tRNA synthetases class I (W and Y) CobA_CobO_BtuR PF02572.10 EXF81524.1 - 0.081 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Helicase_RecD PF05127.9 EXF81524.1 - 0.083 12.5 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Helicase Fanconi_A PF03511.9 EXF81524.1 - 0.1 12.4 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Fanconi anaemia group A protein dCMP_cyt_deam_1 PF00383.17 EXF81525.1 - 1.5e-15 56.6 0.2 1.9e-15 56.3 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EXF81525.1 - 1.1e-09 38.3 0.5 1.1e-08 35.1 0.0 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EXF81525.1 - 0.0042 16.4 1.4 0.6 9.4 0.0 2.2 1 1 1 2 2 2 2 A distinct subfamily of CDD/CDA-like deaminases XOO_2897-deam PF14440.1 EXF81525.1 - 0.055 13.1 0.1 5.2 6.8 0.0 2.0 1 1 1 2 2 2 0 Xanthomonas XOO_2897-like deaminase Fer4_13 PF13370.1 EXF81525.1 - 0.075 13.4 1.2 3.1 8.2 0.1 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain adh_short PF00106.20 EXF81526.1 - 2.9e-18 66.3 0.0 5.7e-18 65.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF81526.1 - 1.7e-17 63.9 0.0 3.1e-17 63.1 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF81526.1 - 3.1e-09 36.7 0.0 2.8e-08 33.6 0.0 1.9 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EXF81526.1 - 0.02 14.8 0.1 2.2 8.2 0.1 2.5 2 1 0 2 2 2 0 NADH(P)-binding DnaJ PF00226.26 EXF81527.1 - 2.9e-25 87.7 2.7 5.7e-25 86.8 1.9 1.5 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EXF81527.1 - 1.1e-21 76.5 0.1 3.9e-18 65.1 0.0 2.9 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EXF81527.1 - 1.6e-13 50.4 19.9 2.9e-13 49.6 13.8 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EXF81527.1 - 0.032 13.8 10.7 0.14 11.8 1.6 2.4 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family zinc-ribbons_6 PF07191.7 EXF81527.1 - 3 7.6 6.6 1.9 8.3 1.2 2.3 2 0 0 2 2 2 0 zinc-ribbons DUF2614 PF11023.3 EXF81527.1 - 4 7.2 5.9 6.2 6.6 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2614) CPSF_A PF03178.10 EXF81528.1 - 6.4e-06 25.4 0.0 3.8e-05 22.9 0.0 2.0 1 1 1 2 2 2 1 CPSF A subunit region PQQ_2 PF13360.1 EXF81528.1 - 0.0068 15.8 0.0 0.18 11.2 0.0 2.7 3 0 0 3 3 3 1 PQQ-like domain WD40 PF00400.27 EXF81528.1 - 0.0089 15.8 0.9 10 6.1 0.0 3.6 4 0 0 4 4 4 1 WD domain, G-beta repeat Ribosomal_L10 PF00466.15 EXF81529.1 - 9.9e-25 86.3 0.1 2e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EXF81529.1 - 3.9e-19 68.8 6.5 5.9e-19 68.2 2.4 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein VirE_N PF08800.5 EXF81529.1 - 0.065 12.9 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 VirE N-terminal domain MutS_V PF00488.16 EXF81530.1 - 4e-79 265.3 0.0 6.9e-79 264.5 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EXF81530.1 - 2.4e-40 138.4 7.3 3.9e-40 137.8 5.1 1.3 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EXF81530.1 - 2.5e-19 69.3 0.0 6.1e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EXF81530.1 - 1.4e-07 31.6 0.0 3.3e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.13 EXF81530.1 - 0.031 14.4 0.0 0.098 12.8 0.0 1.9 2 0 0 2 2 2 0 MutS family domain IV AAA_29 PF13555.1 EXF81530.1 - 0.041 13.4 1.0 0.15 11.5 0.0 2.3 1 1 1 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.1 EXF81530.1 - 0.26 11.5 0.0 0.5 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain TFIIA PF03153.8 EXF81531.1 - 1.2e-06 28.7 5.4 1.8e-06 28.1 3.7 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Nop14 PF04147.7 EXF81531.1 - 1.6 6.5 10.2 1.9 6.2 7.1 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EXF81531.1 - 5.1 6.2 12.7 10 5.2 8.8 1.5 1 0 0 1 1 1 0 SDA1 Glyco_hydro_38 PF01074.17 EXF81532.1 - 7.2e-92 307.5 1.2 1.2e-91 306.8 0.8 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EXF81532.1 - 2.9e-74 250.5 0.1 5.2e-74 249.7 0.1 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EXF81532.1 - 2.6e-26 91.6 0.0 6e-26 90.4 0.0 1.7 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Pkinase PF00069.20 EXF81533.1 - 2.5e-34 118.6 0.0 2.6e-21 75.9 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EXF81533.1 - 1.7e-11 43.6 0.0 0.0011 18.1 0.0 3.0 3 0 0 3 3 3 3 Protein tyrosine kinase APH PF01636.18 EXF81533.1 - 0.00062 19.5 0.1 0.0049 16.6 0.0 2.1 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EXF81533.1 - 0.0023 16.9 0.0 0.89 8.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like CAP_GLY PF01302.20 EXF81534.1 - 6.6e-17 60.9 0.2 1.5e-16 59.8 0.2 1.6 1 0 0 1 1 1 1 CAP-Gly domain AAA_13 PF13166.1 EXF81534.1 - 0.0012 17.4 8.6 0.0023 16.4 4.4 2.1 1 1 1 2 2 2 1 AAA domain DUF3584 PF12128.3 EXF81534.1 - 0.01 13.2 20.6 0.014 12.7 14.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) NPV_P10 PF05531.7 EXF81534.1 - 0.011 15.9 4.3 2.4 8.4 0.1 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.6 EXF81534.1 - 0.091 11.4 17.8 0.1 11.2 3.9 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein Mod_r PF07200.8 EXF81534.1 - 0.45 10.4 14.6 0.056 13.3 1.9 3.0 3 0 0 3 3 3 0 Modifier of rudimentary (Mod(r)) protein Reo_sigmaC PF04582.7 EXF81534.1 - 0.49 9.5 9.9 0.5 9.4 2.6 2.9 2 1 1 3 3 3 0 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 EXF81534.1 - 0.74 9.6 34.9 0.17 11.7 1.6 5.6 4 1 2 6 6 6 0 TATA element modulatory factor 1 DNA binding BLOC1_2 PF10046.4 EXF81534.1 - 1.7 8.7 11.9 0.25 11.5 0.6 3.3 4 0 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Cytochrom_B562 PF07361.6 EXF81534.1 - 2.1 8.7 6.6 22 5.5 0.6 3.0 1 1 0 2 2 2 0 Cytochrome b562 EMP24_GP25L PF01105.19 EXF81534.1 - 3.2 7.4 7.5 2.1 8.0 0.9 2.6 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD DUF4407 PF14362.1 EXF81534.1 - 4.4 6.1 23.1 1.1 8.1 6.2 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4407) DivIC PF04977.10 EXF81534.1 - 8.2 5.9 20.9 0.13 11.7 0.7 4.9 4 1 2 6 6 6 0 Septum formation initiator Nop14 PF04147.7 EXF81536.1 - 4.1e-251 835.5 33.1 5e-251 835.2 22.9 1.1 1 0 0 1 1 1 1 Nop14-like family DUF4187 PF13821.1 EXF81537.1 - 7.2e-19 67.1 4.7 7.2e-19 67.1 3.2 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) G-patch PF01585.18 EXF81537.1 - 9.2e-05 22.1 13.6 0.00061 19.5 9.4 2.2 1 1 0 1 1 1 1 G-patch domain PPR_2 PF13041.1 EXF81538.1 - 3.2e-10 39.8 0.0 8.6e-06 25.6 0.0 4.6 4 0 0 4 4 4 2 PPR repeat family PPR PF01535.15 EXF81538.1 - 0.00017 21.3 1.0 3 7.9 0.0 4.9 5 0 0 5 5 5 2 PPR repeat PPR_3 PF13812.1 EXF81538.1 - 0.0056 16.8 0.5 44 4.7 0.0 5.6 6 0 0 6 6 6 1 Pentatricopeptide repeat domain RTC PF01137.16 EXF81539.1 - 4.4e-30 104.1 0.1 5.8e-30 103.7 0.1 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EXF81539.1 - 6.2e-30 103.2 0.1 1.1e-29 102.4 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain DUF1746 PF08508.5 EXF81540.1 - 7.1e-37 125.8 0.1 9.8e-37 125.4 0.1 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1746) tRNA-synt_2d PF01409.15 EXF81541.1 - 5.1e-86 287.8 0.0 7.3e-86 287.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) tRNA-synt_2 PF00152.15 EXF81541.1 - 4.8e-06 25.5 3.3 0.00011 21.1 0.1 3.4 3 1 1 4 4 4 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.20 EXF81541.1 - 0.00047 19.7 0.0 0.00096 18.7 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) CPSase_L_D2 PF02786.12 EXF81542.1 - 1.2e-107 357.9 0.0 1.2e-83 279.6 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.14 EXF81542.1 - 6.5e-40 135.7 0.0 1.6e-39 134.4 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ATP-grasp_4 PF13535.1 EXF81542.1 - 4e-39 134.2 0.9 7.2e-22 78.0 0.0 2.9 3 0 0 3 3 3 2 ATP-grasp domain CPSase_L_chain PF00289.17 EXF81542.1 - 4.3e-37 126.5 0.0 2.3e-17 63.0 0.0 2.8 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATPgrasp_Ter PF15632.1 EXF81542.1 - 1.1e-24 86.7 0.0 1.8e-09 36.8 0.0 3.6 3 1 0 3 3 3 3 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EXF81542.1 - 2.4e-21 75.8 0.0 4.6e-10 39.1 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EXF81542.1 - 3.6e-17 62.4 0.9 7e-08 32.1 0.0 2.7 3 0 0 3 3 3 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EXF81542.1 - 2.5e-09 36.9 0.0 2.8e-05 23.6 0.0 2.7 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.9 EXF81542.1 - 6.8e-07 29.2 0.3 0.065 13.1 0.0 3.2 3 0 0 3 3 3 2 ATP-grasp domain GARS_A PF01071.14 EXF81542.1 - 2.2e-06 27.3 0.4 0.0094 15.5 0.1 2.7 2 0 0 2 2 2 2 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.1 EXF81542.1 - 3.9e-05 22.9 0.1 0.17 11.0 0.0 2.6 2 0 0 2 2 2 2 ATP-grasp domain Pox_I6 PF04595.8 EXF81542.1 - 0.19 10.4 0.0 0.32 9.6 0.0 1.2 1 0 0 1 1 1 0 Poxvirus I6-like family NPL4 PF05021.10 EXF81543.1 - 1.1e-126 422.2 0.0 1.3e-126 421.9 0.0 1.1 1 0 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.10 EXF81543.1 - 3.4e-71 237.6 0.1 5.9e-71 236.8 0.1 1.4 1 0 0 1 1 1 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.3 EXF81543.1 - 0.0023 18.1 0.0 0.011 16.0 0.0 2.1 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 DUF4451 PF14616.1 EXF81543.1 - 0.087 12.5 0.4 0.19 11.4 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) Sec66 PF09802.4 EXF81544.1 - 1.1e-79 266.2 0.3 1.3e-79 266.0 0.2 1.0 1 0 0 1 1 1 1 Preprotein translocase subunit Sec66 PaREP1 PF05942.6 EXF81544.1 - 2.4 8.0 5.5 3.2 7.6 0.5 2.2 1 1 1 2 2 2 0 Archaeal PaREP1/PaREP8 family ORC3_N PF07034.6 EXF81546.1 - 3.8e-37 127.9 0.8 1.3e-36 126.2 0.6 1.8 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus Pox_I6 PF04595.8 EXF81546.1 - 0.043 12.5 0.0 0.078 11.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus I6-like family PWWP PF00855.12 EXF81547.1 - 4.7e-14 52.3 0.0 4.7e-14 52.3 0.0 3.8 3 1 1 4 4 4 1 PWWP domain Med26 PF08711.6 EXF81547.1 - 0.0039 16.6 0.4 0.017 14.5 0.3 2.1 2 0 0 2 2 2 1 TFIIS helical bundle-like domain Sec63 PF02889.11 EXF81548.1 - 2.1e-189 628.3 0.7 4.2e-108 361.2 0.0 2.8 2 1 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EXF81548.1 - 4e-54 182.6 0.1 3.4e-31 108.0 0.0 3.9 4 0 0 4 4 4 2 DEAD/DEAH box helicase ResIII PF04851.10 EXF81548.1 - 1.9e-17 63.6 2.4 1.4e-08 34.8 0.0 3.4 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EXF81548.1 - 4.9e-10 39.1 0.0 4.1e-09 36.1 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EXF81548.1 - 3.2e-05 24.0 0.6 0.014 15.5 0.1 3.5 2 2 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EXF81548.1 - 0.00049 19.6 0.1 2.3 7.5 0.0 3.9 3 1 1 4 4 4 2 AAA-like domain PhoH PF02562.11 EXF81548.1 - 0.005 16.1 0.0 0.46 9.6 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_19 PF13245.1 EXF81548.1 - 0.069 12.9 0.0 8.1 6.2 0.0 2.9 2 0 0 2 2 2 0 Part of AAA domain AAA_23 PF13476.1 EXF81548.1 - 2.2 8.5 6.0 15 5.8 0.0 3.8 4 0 0 4 4 4 0 AAA domain 3H PF02829.9 EXF81549.1 - 0.19 11.7 1.4 4.6 7.3 0.2 2.6 2 0 0 2 2 2 0 3H domain AAA PF00004.24 EXF81550.1 - 8.7e-17 61.5 0.1 3.2e-16 59.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EXF81550.1 - 2.2e-13 50.2 0.0 8.3e-13 48.3 0.0 1.9 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rep_fac_C PF08542.6 EXF81550.1 - 2.2e-12 46.7 0.0 5e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 EXF81550.1 - 4e-12 45.5 0.1 2.1e-08 33.3 0.0 2.1 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EXF81550.1 - 2.5e-07 30.8 0.0 5.4e-06 26.5 0.0 2.8 2 2 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EXF81550.1 - 7.5e-07 28.4 0.0 2.2e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EXF81550.1 - 1.9e-05 24.3 0.0 4.4e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EXF81550.1 - 2.8e-05 24.1 0.1 0.00087 19.3 0.0 2.7 2 1 0 3 3 3 1 AAA ATPase domain AAA_11 PF13086.1 EXF81550.1 - 5.7e-05 22.8 0.0 9.7e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EXF81550.1 - 8.9e-05 22.3 0.0 0.00017 21.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.8 EXF81550.1 - 0.00019 21.0 0.0 0.00036 20.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.16 EXF81550.1 - 0.00026 20.1 0.0 0.012 14.8 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EXF81550.1 - 0.0003 19.8 0.0 0.00054 19.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 EXF81550.1 - 0.001 19.8 0.0 0.0025 18.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EXF81550.1 - 0.0033 16.3 0.0 0.0053 15.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_30 PF13604.1 EXF81550.1 - 0.0037 16.8 0.0 0.032 13.8 0.0 2.4 2 2 1 3 3 3 1 AAA domain AAA_24 PF13479.1 EXF81550.1 - 0.0039 16.8 0.3 0.01 15.4 0.2 1.8 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.8 EXF81550.1 - 0.0047 15.6 0.0 0.31 9.7 0.0 2.2 2 0 0 2 2 2 1 TIP49 C-terminus AAA_5 PF07728.9 EXF81550.1 - 0.0052 16.5 0.1 0.025 14.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.1 EXF81550.1 - 0.0059 16.5 0.0 0.013 15.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EXF81550.1 - 0.0072 15.7 0.1 0.024 14.0 0.1 2.2 1 1 0 1 1 1 1 AAA domain FtsK_SpoIIIE PF01580.13 EXF81550.1 - 0.0087 15.5 0.0 0.022 14.2 0.0 1.7 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_18 PF13238.1 EXF81550.1 - 0.017 15.4 0.0 0.04 14.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EXF81550.1 - 0.03 14.4 0.0 0.067 13.3 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_3 PF07726.6 EXF81550.1 - 0.036 13.6 0.0 0.22 11.1 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SNF2_N PF00176.18 EXF81550.1 - 0.041 12.6 0.0 1.5 7.5 0.0 2.1 1 1 0 2 2 2 0 SNF2 family N-terminal domain AAA_10 PF12846.2 EXF81550.1 - 0.054 12.9 0.1 0.7 9.2 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain PhoH PF02562.11 EXF81550.1 - 0.055 12.7 0.1 2.6 7.2 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_33 PF13671.1 EXF81550.1 - 0.084 12.7 0.0 0.18 11.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain DEAD PF00270.24 EXF81550.1 - 0.09 12.2 0.3 1.4 8.3 0.0 2.6 2 1 1 3 3 3 0 DEAD/DEAH box helicase AAA_23 PF13476.1 EXF81550.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain ResIII PF04851.10 EXF81550.1 - 0.12 12.1 0.0 0.5 10.1 0.0 1.9 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit UQ_con PF00179.21 EXF81551.1 - 4.2e-44 149.3 0.0 1e-28 99.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin-conjugating enzyme TcpQ PF10671.4 EXF81551.1 - 0.0063 16.3 0.0 0.019 14.8 0.0 1.8 2 0 0 2 2 2 1 Toxin co-regulated pilus biosynthesis protein Q RWD PF05773.17 EXF81551.1 - 0.022 14.6 0.0 2.6 7.9 0.0 2.5 1 1 1 2 2 2 0 RWD domain DUF2267 PF10025.4 EXF81551.1 - 0.087 12.8 0.1 0.25 11.4 0.1 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) DUF2417 PF10329.4 EXF81554.1 - 2.7e-75 252.7 1.5 3.4e-75 252.4 1.1 1.1 1 0 0 1 1 1 1 Region of unknown function (DUF2417) Abhydrolase_6 PF12697.2 EXF81554.1 - 8.4e-08 32.3 0.2 1.5e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Oxysterol_BP PF01237.13 EXF81556.1 - 4.7e-88 295.0 0.0 6e-88 294.7 0.0 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein zf-CCCH PF00642.19 EXF81557.1 - 1.7e-08 33.9 18.1 4.6e-07 29.3 1.6 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.1 EXF81557.1 - 0.00025 20.8 0.0 0.00039 20.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EXF81557.1 - 0.01 15.4 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Tachystatin_B PF11478.3 EXF81557.1 - 4.6 7.0 9.0 0.4 10.4 1.3 2.6 3 0 0 3 3 3 0 Antimicrobial chitin binding protein tachystatin B ELMO_CED12 PF04727.8 EXF81558.1 - 4.1e-49 166.3 0.1 9.5e-49 165.2 0.0 1.6 2 0 0 2 2 2 1 ELMO/CED-12 family DUF3361 PF11841.3 EXF81558.1 - 0.0008 19.1 0.1 0.089 12.5 0.0 2.8 2 0 0 2 2 2 2 Domain of unknown function (DUF3361) Pirin PF02678.11 EXF81559.1 - 1.8e-30 104.9 0.1 1.8e-29 101.7 0.0 2.1 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.8 EXF81559.1 - 2e-25 88.8 0.1 1.6e-24 85.9 0.0 2.0 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EXF81559.1 - 1.1e-08 34.4 3.4 5.8e-05 22.5 1.0 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EXF81559.1 - 0.009 15.3 0.2 1.1 8.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) zf-GRF PF06839.7 EXF81560.1 - 1.4e-08 34.4 7.8 2.5e-08 33.7 5.4 1.4 1 0 0 1 1 1 1 GRF zinc finger TMF_DNA_bd PF12329.3 EXF81560.1 - 0.00075 19.2 0.4 0.0016 18.2 0.3 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding DUF1204 PF06721.6 EXF81560.1 - 0.027 13.7 1.7 0.048 12.9 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) DUF3818 PF12825.2 EXF81561.1 - 1.7e-135 451.1 2.6 2.5e-135 450.5 1.8 1.2 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) PXB PF12828.2 EXF81561.1 - 7e-43 145.5 1.7 1.5e-42 144.4 0.3 2.1 2 0 0 2 2 2 1 PX-associated PX PF00787.19 EXF81561.1 - 6.3e-17 61.4 0.0 4.2e-16 58.7 0.0 2.5 2 1 0 2 2 2 1 PX domain Myc_N PF01056.13 EXF81561.1 - 0.00066 18.9 2.2 0.0012 18.0 1.6 1.3 1 0 0 1 1 1 1 Myc amino-terminal region TMEM151 PF14857.1 EXF81562.1 - 0.078 11.5 3.2 0.12 10.9 2.2 1.2 1 0 0 1 1 1 0 TMEM151 family DUF2077 PF09850.4 EXF81562.1 - 0.16 11.3 1.5 0.48 9.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2077) Zip PF02535.17 EXF81562.1 - 1.3 7.9 5.0 2.3 7.1 3.5 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Cgr1 PF03879.9 EXF81563.1 - 2.3e-39 133.9 32.2 2.6e-39 133.7 22.3 1.0 1 0 0 1 1 1 1 Cgr1 family Prismane PF03063.15 EXF81563.1 - 0.47 8.7 6.2 0.52 8.6 4.3 1.1 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family RR_TM4-6 PF06459.7 EXF81563.1 - 0.61 9.9 17.0 0.71 9.7 11.8 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TROVE PF05731.6 EXF81563.1 - 1.8 7.2 15.8 2.1 7.0 10.9 1.0 1 0 0 1 1 1 0 TROVE domain Ax_dynein_light PF10211.4 EXF81563.1 - 2.3 8.0 16.4 3 7.6 11.4 1.3 1 0 0 1 1 1 0 Axonemal dynein light chain PRP1_N PF06424.7 EXF81563.1 - 3.3 8.0 16.8 2.2 8.5 10.9 1.3 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal EzrA PF06160.7 EXF81564.1 - 0.19 9.9 0.3 0.27 9.3 0.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA UQ_con PF00179.21 EXF81565.1 - 6.1e-30 103.4 0.0 7.8e-30 103.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EXF81565.1 - 0.002 17.8 0.0 0.0029 17.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EXF81565.1 - 0.08 12.8 0.0 0.09 12.6 0.0 1.3 1 0 0 1 1 1 0 RWD domain Anp1 PF03452.9 EXF81566.1 - 7.5e-110 366.3 0.0 9.3e-110 366.0 0.0 1.0 1 0 0 1 1 1 1 Anp1 Glycos_transf_2 PF00535.21 EXF81566.1 - 0.084 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 CENP-U PF13097.1 EXF81566.1 - 0.26 11.2 2.5 0.44 10.4 1.7 1.3 1 0 0 1 1 1 0 CENP-A nucleosome associated complex (NAC) subunit RRM_1 PF00076.17 EXF81567.1 - 5.4e-17 61.1 0.0 9e-17 60.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF81567.1 - 1.5e-14 53.7 0.0 2.5e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF81567.1 - 2.6e-07 30.3 0.0 4.1e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FoP_duplication PF13865.1 EXF81567.1 - 0.0043 17.4 15.9 0.0043 17.4 11.0 5.4 4 2 3 7 7 7 1 C-terminal duplication domain of Friend of PRMT1 TFIIF_alpha PF05793.7 EXF81568.1 - 4.6 5.4 10.6 5.7 5.1 7.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF1932 PF09130.6 EXF81569.1 - 1e-21 76.4 0.1 2.1e-21 75.4 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1932) NAD_binding_2 PF03446.10 EXF81569.1 - 2.3e-08 34.0 0.0 3.8e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EXF81569.1 - 6.9e-08 32.8 0.1 1.8e-07 31.4 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 EXF81569.1 - 8.1e-05 22.6 0.2 0.003 17.6 0.1 2.2 2 0 0 2 2 2 1 NADH(P)-binding 3HCDH_N PF02737.13 EXF81569.1 - 0.0024 17.5 0.1 0.0045 16.6 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EXF81569.1 - 0.024 13.7 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain YjeF_N PF03853.10 EXF81569.1 - 0.052 13.1 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 YjeF-related protein N-terminus tRNA-synt_1 PF00133.17 EXF81571.1 - 1.5e-212 706.8 0.0 8.6e-212 704.3 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EXF81571.1 - 3.7e-33 114.4 0.1 1.5e-32 112.4 0.1 2.1 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EXF81571.1 - 2.5e-13 49.4 0.0 7e-05 21.6 0.0 4.4 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EXF81571.1 - 1.2e-10 40.9 6.7 6.9e-09 35.2 0.0 2.9 2 1 1 3 3 3 2 Leucyl-tRNA synthetase, Domain 2 DUF3464 PF11947.3 EXF81571.1 - 5.3 6.4 10.3 12 5.3 7.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) SHR3_chaperone PF08229.6 EXF81572.1 - 9.4e-73 243.3 0.0 1.1e-72 243.1 0.0 1.0 1 0 0 1 1 1 1 ER membrane protein SH3 SRA1 PF07304.6 EXF81573.1 - 0.045 13.4 0.1 0.045 13.4 0.1 3.0 3 0 0 3 3 3 0 Steroid receptor RNA activator (SRA1) MSP1_C PF07462.6 EXF81573.1 - 4.6 5.5 5.9 8.4 4.6 4.1 1.3 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus AAA_11 PF13086.1 EXF81574.1 - 4.8e-49 167.0 0.5 2.6e-47 161.4 0.1 2.6 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EXF81574.1 - 1.7e-46 158.1 0.0 9.5e-46 155.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.4 EXF81574.1 - 0.013 14.5 0.2 0.025 13.5 0.1 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) 4HB_MCP_1 PF12729.2 EXF81574.1 - 0.034 13.4 0.1 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Viral_helicase1 PF01443.13 EXF81574.1 - 0.056 12.9 0.0 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF202 PF02656.10 EXF81575.1 - 6.2e-25 87.2 1.2 6.2e-25 87.2 0.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Mito_fiss_reg PF05308.6 EXF81575.1 - 0.19 11.1 9.8 0.36 10.1 6.8 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.14 EXF81575.1 - 4.6 6.4 14.9 8 5.6 10.3 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal TMEM171 PF15471.1 EXF81575.1 - 7.1 5.3 6.9 12 4.6 4.8 1.4 1 0 0 1 1 1 0 Transmembrane protein family 171 zf-C2H2_4 PF13894.1 EXF81578.1 - 1.8e-09 37.2 12.8 0.00011 22.2 3.6 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF81578.1 - 4.2e-09 36.2 14.8 3.9e-06 26.8 1.8 3.4 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EXF81578.1 - 3.6e-08 33.2 14.7 6.4e-07 29.3 4.4 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EXF81578.1 - 3.2e-06 27.1 7.2 0.00032 20.7 0.7 2.5 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EXF81578.1 - 4.1e-06 26.8 6.5 4.2e-05 23.5 0.2 2.9 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EXF81578.1 - 0.0064 16.3 10.6 0.0068 16.2 0.8 2.8 2 1 0 2 2 2 1 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EXF81578.1 - 0.64 10.1 5.1 10 6.3 0.3 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-BED PF02892.10 EXF81578.1 - 1.7 8.4 8.5 1.9 8.3 3.2 2.4 1 1 1 2 2 2 0 BED zinc finger RAP1 PF07218.6 EXF81578.1 - 8.2 4.3 7.9 7.2 4.5 3.6 1.9 2 0 0 2 2 2 0 Rhoptry-associated protein 1 (RAP-1) ATP_bind_4 PF01902.12 EXF81579.1 - 1.7e-19 70.1 0.0 1.9e-15 56.8 0.0 3.3 3 1 0 3 3 3 2 ATP-binding region Ribonuc_L-PSP PF01042.16 EXF81579.1 - 1.3e-11 44.3 0.1 7.5e-08 32.1 0.0 3.5 3 1 0 3 3 3 2 Endoribonuclease L-PSP Acyl_transf_3 PF01757.17 EXF81580.1 - 8.6e-26 90.5 34.1 1.3e-25 90.0 23.7 1.3 1 0 0 1 1 1 1 Acyltransferase family TPR_11 PF13414.1 EXF81582.1 - 3.4e-20 71.4 5.3 2.8e-15 55.7 0.0 2.6 1 1 1 2 2 2 2 TPR repeat U-box PF04564.10 EXF81582.1 - 1.1e-18 66.9 0.0 2.1e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain TPR_2 PF07719.12 EXF81582.1 - 2.8e-10 39.3 5.9 0.00013 21.6 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EXF81582.1 - 1.4e-08 35.1 0.8 0.00018 22.0 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EXF81582.1 - 1.3e-07 30.9 4.8 0.0068 15.9 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EXF81582.1 - 1.9e-06 27.6 6.3 0.0007 19.4 1.8 2.8 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EXF81582.1 - 2.3e-06 27.7 4.6 0.00053 20.3 0.1 3.0 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EXF81582.1 - 4.3e-06 26.9 5.4 0.0025 18.1 0.2 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EXF81582.1 - 0.00013 21.9 4.5 0.053 13.7 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EXF81582.1 - 0.0013 18.8 1.8 0.0039 17.2 1.0 2.1 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.1 EXF81582.1 - 0.004 16.9 0.2 0.021 14.6 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EXF81582.1 - 0.0072 16.2 6.0 0.22 11.5 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EXF81582.1 - 0.011 15.3 2.1 0.78 9.6 0.6 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3856 PF12968.2 EXF81582.1 - 0.092 12.5 1.4 1.8 8.3 0.1 2.8 3 0 0 3 3 3 0 Domain of Unknown Function (DUF3856) TPR_6 PF13174.1 EXF81582.1 - 0.11 13.0 3.2 20 5.9 0.8 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 EXF81582.1 - 0.12 12.8 0.4 5.7 7.6 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EXF81582.1 - 0.52 10.2 5.3 2.8 7.9 0.0 3.9 4 1 1 5 5 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EXF81582.1 - 0.7 9.8 3.0 1.6 8.6 0.3 2.9 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat MAP65_ASE1 PF03999.7 EXF81585.1 - 9.5 4.6 6.0 10 4.5 4.2 1.0 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DIE2_ALG10 PF04922.7 EXF81586.1 - 1.8e-71 241.2 18.4 9.3e-54 182.8 1.3 3.4 3 0 0 3 3 3 3 DIE2/ALG10 family GST_C_2 PF13410.1 EXF81586.1 - 0.59 10.0 5.1 2.9 7.8 0.2 3.0 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain QCR10 PF09796.4 EXF81587.1 - 9.4e-24 82.8 0.3 1.3e-23 82.4 0.2 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) UCR_6-4kD PF08997.5 EXF81587.1 - 0.00046 19.8 0.4 0.0018 17.9 0.3 2.1 1 1 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Med4 PF10018.4 EXF81588.1 - 7.6e-35 120.0 2.4 7.6e-35 120.0 1.6 1.8 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Uds1 PF15456.1 EXF81588.1 - 0.12 12.3 10.3 0.6 10.1 3.0 2.6 3 0 0 3 3 3 0 Up-regulated During Septation Atg14 PF10186.4 EXF81588.1 - 0.15 10.9 4.9 1.8 7.3 0.7 2.1 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 EMP70 PF02990.11 EXF81589.1 - 1.5e-191 637.4 3.8 1.9e-191 637.0 2.7 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 NfeD PF01957.13 EXF81589.1 - 0.044 13.9 0.0 0.044 13.9 0.0 4.3 2 2 3 5 5 5 0 NfeD-like C-terminal, partner-binding PIRT PF15099.1 EXF81589.1 - 0.22 10.7 0.8 0.45 9.7 0.6 1.5 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family Sas10_Utp3 PF04000.10 EXF81590.1 - 8e-16 58.0 1.2 1.9e-15 56.7 0.8 1.7 1 0 0 1 1 1 1 Sas10/Utp3/C1D family Pyr_redox_3 PF13738.1 EXF81591.1 - 1.6e-21 77.3 0.1 5.8e-21 75.4 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EXF81591.1 - 5.1e-18 64.5 0.0 2.5e-17 62.2 0.0 1.9 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EXF81591.1 - 2.2e-12 47.3 0.0 5.1e-10 39.5 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF81591.1 - 4.1e-10 39.0 0.1 3.2e-08 32.8 0.0 2.9 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EXF81591.1 - 3.9e-06 26.7 0.4 1.5e-05 24.8 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF81591.1 - 5e-06 25.6 1.5 5.8e-06 25.4 0.0 1.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EXF81591.1 - 0.00024 21.4 5.6 0.055 13.8 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EXF81591.1 - 0.0012 18.9 0.1 1.2 9.2 0.0 2.7 3 0 0 3 3 3 2 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EXF81591.1 - 0.002 17.7 0.3 0.0032 17.1 0.2 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EXF81591.1 - 0.014 13.8 1.0 0.27 9.6 0.4 2.6 3 0 0 3 3 3 0 HI0933-like protein NAD_binding_9 PF13454.1 EXF81591.1 - 0.023 14.4 3.2 0.27 11.0 0.6 3.3 3 1 0 3 3 3 0 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.16 EXF81591.1 - 0.034 13.7 0.9 8.1 5.9 0.0 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EXF81591.1 - 0.069 13.4 0.0 2.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_2 PF00890.19 EXF81591.1 - 1.2 7.9 7.9 0.025 13.4 0.9 1.5 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 EXF81591.1 - 1.3 7.8 3.5 0.83 8.4 0.6 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A TPR_12 PF13424.1 EXF81592.1 - 2.5e-09 36.9 27.1 0.00012 21.9 0.4 7.8 8 1 1 9 9 9 4 Tetratricopeptide repeat AAA_16 PF13191.1 EXF81592.1 - 5.3e-07 29.8 0.0 1.8e-06 28.0 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EXF81592.1 - 3.9e-06 27.0 0.0 2.5e-05 24.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EXF81592.1 - 2.2e-05 24.1 0.0 9.1e-05 22.1 0.0 2.1 1 0 0 1 1 1 1 NACHT domain TPR_7 PF13176.1 EXF81592.1 - 4.5e-05 22.9 11.9 1.6 8.7 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.23 EXF81592.1 - 0.001 18.5 4.8 10 5.9 0.1 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EXF81592.1 - 0.0046 17.3 1.4 20 5.9 0.2 4.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EXF81592.1 - 0.075 13.3 2.5 32 4.9 0.1 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EXF81592.1 - 0.31 11.7 9.2 1.1e+02 3.9 0.0 6.4 8 0 0 8 8 8 0 Tetratricopeptide repeat Toxin_50 PF15530.1 EXF81594.1 - 0.12 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative toxin 50 PhoD PF09423.5 EXF81595.1 - 3.3e-155 517.0 5.4 3.8e-155 516.8 3.7 1.0 1 0 0 1 1 1 1 PhoD-like phosphatase Transp_cyt_pur PF02133.10 EXF81596.1 - 1.7e-154 514.6 33.5 2e-154 514.4 23.2 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF3188 PF11384.3 EXF81597.1 - 0.067 12.7 0.2 0.12 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) BmKX PF09132.5 EXF81598.1 - 0.34 10.8 0.1 0.34 10.8 0.1 2.9 3 0 0 3 3 3 0 BmKX adh_short_C2 PF13561.1 EXF81599.1 - 2.6e-23 83.0 0.0 6.6e-16 58.7 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EXF81599.1 - 2e-18 66.8 0.4 1.4e-16 60.8 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EXF81599.1 - 9.9e-10 38.3 0.0 2.4e-09 37.0 0.0 1.6 1 1 1 2 2 2 1 KR domain Epimerase PF01370.16 EXF81599.1 - 0.012 15.0 0.0 2.7 7.3 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF2703 PF10865.3 EXF81599.1 - 0.066 13.1 0.1 0.24 11.3 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2703) Transketolase_N PF00456.16 EXF81600.1 - 3.4e-127 423.8 0.1 7.1e-127 422.8 0.1 1.4 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EXF81600.1 - 4.3e-38 130.5 0.0 1.2e-37 129.1 0.0 1.7 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 EXF81600.1 - 3e-09 36.2 0.0 2.1e-07 30.1 0.0 2.4 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EXF81600.1 - 1.7e-08 33.5 0.1 3.1e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_C PF02780.15 EXF81600.1 - 2e-08 34.2 0.0 5.2e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Fungal_trans_2 PF11951.3 EXF81601.1 - 2.5e-18 65.8 1.3 4.2e-18 65.0 0.9 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF81601.1 - 4.6e-07 29.6 12.1 8e-07 28.8 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EXF81602.1 - 1e-105 353.9 22.4 1.2e-105 353.7 15.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF81602.1 - 8e-29 100.4 56.4 1e-23 83.6 17.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EXF81602.1 - 0.0067 14.5 0.6 0.0067 14.5 0.4 1.6 2 0 0 2 2 2 1 Organic Anion Transporter Polypeptide (OATP) family ECH PF00378.15 EXF81603.1 - 2.5e-45 154.5 0.0 1.2e-33 116.2 0.3 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase family MFS_1 PF07690.11 EXF81605.1 - 1.6e-17 63.2 22.6 2.7e-17 62.5 15.7 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EXF81605.1 - 1.9e-07 29.7 5.3 2.2e-07 29.4 3.7 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EXF81605.1 - 0.001 17.7 7.2 0.001 17.7 5.0 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter Cation_ATPase_C PF00689.16 EXF81605.1 - 0.0055 16.2 1.7 0.0055 16.2 1.2 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus DUF4341 PF14241.1 EXF81605.1 - 0.049 13.3 1.1 0.049 13.3 0.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4341) Glyco_hydro_28 PF00295.12 EXF81607.1 - 1.8e-42 145.4 1.1 2.4e-42 145.0 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 adh_short PF00106.20 EXF81609.1 - 4.5e-21 75.4 0.0 6.3e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF81609.1 - 7.1e-11 42.0 0.0 9.2e-11 41.7 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF81609.1 - 8.5e-10 38.8 0.0 1.2e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EXF81609.1 - 0.00017 20.6 0.0 0.0002 20.3 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EXF81609.1 - 0.0037 17.0 0.1 0.007 16.1 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EXF81609.1 - 0.0079 15.6 0.0 0.015 14.7 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_tran_WecB PF03808.8 EXF81609.1 - 0.035 13.5 0.0 0.062 12.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Zn_clus PF00172.13 EXF81610.1 - 1.3e-07 31.3 13.0 1.3e-07 31.3 9.0 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Coatomer_WDAD PF04053.9 EXF81611.1 - 1.7e-173 577.4 0.0 9.6e-173 575.0 0.0 2.0 2 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.27 EXF81611.1 - 2e-48 160.5 6.2 4.1e-10 39.1 0.1 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EXF81611.1 - 5.9e-06 24.7 2.4 0.0048 15.1 0.0 4.2 2 2 2 4 4 4 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EXF81611.1 - 0.00035 20.3 0.0 0.29 10.9 0.0 3.3 2 1 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region YmzC PF14157.1 EXF81611.1 - 0.024 14.4 0.1 41 4.0 0.0 4.1 5 0 0 5 5 5 0 YmzC-like protein Mannitol_dh_C PF08125.8 EXF81612.1 - 4.5e-45 153.7 0.0 6.5e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EXF81612.1 - 1.6e-18 67.0 0.0 4.6e-18 65.5 0.0 1.8 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain 3HCDH_N PF02737.13 EXF81612.1 - 0.0029 17.2 1.1 0.019 14.6 0.0 2.7 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EXF81612.1 - 0.0037 16.6 0.4 0.012 15.0 0.1 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 EXF81612.1 - 0.0047 16.3 0.2 0.54 9.6 0.0 3.1 3 1 0 3 3 3 1 Ketopantoate reductase PanE/ApbA TauD PF02668.11 EXF81612.1 - 0.12 12.0 0.0 3.9 7.0 0.0 2.3 2 0 0 2 2 2 0 Taurine catabolism dioxygenase TauD, TfdA family PGI PF00342.14 EXF81613.1 - 2.2e-203 676.1 0.3 2.5e-203 675.8 0.2 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Pkinase_C PF00433.19 EXF81614.1 - 1.1e-11 45.0 2.8 3.9e-11 43.3 1.9 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain MFS_1 PF07690.11 EXF81615.1 - 3e-36 124.8 40.3 5.2e-25 87.9 15.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF81615.1 - 7.4e-13 47.5 14.9 3.1e-12 45.5 10.3 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EXF81615.1 - 5.8e-08 31.7 12.7 5.8e-08 31.7 8.8 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.8 EXF81615.1 - 1.3 7.0 16.0 0.25 9.4 5.2 2.5 2 1 0 2 2 2 0 Transmembrane secretion effector GMC_oxred_N PF00732.14 EXF81616.1 - 9.1e-79 264.6 0.0 1.3e-78 264.1 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF81616.1 - 1.7e-35 122.4 0.2 4.1e-35 121.1 0.1 1.7 1 1 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EXF81616.1 - 7.8e-06 25.0 0.0 0.0089 14.9 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF81616.1 - 0.00063 18.6 0.0 0.62 8.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EXF81616.1 - 0.0037 16.2 0.0 0.0058 15.6 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EXF81616.1 - 0.02 13.9 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 EXF81616.1 - 0.044 13.6 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF81616.1 - 0.18 12.2 0.2 0.75 10.2 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EXF81616.1 - 0.18 11.8 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 TrkA-N domain FMN_dh PF01070.13 EXF81617.1 - 1.4e-107 359.6 0.0 1.7e-107 359.4 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Glu_synthase PF01645.12 EXF81617.1 - 0.00019 20.4 0.1 0.00029 19.8 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EXF81617.1 - 0.00028 19.9 0.2 0.00047 19.1 0.1 1.3 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EXF81617.1 - 0.0074 15.5 0.5 0.066 12.4 0.2 2.2 1 1 1 2 2 2 2 Histidine biosynthesis protein AMP-binding PF00501.23 EXF81618.1 - 3.4e-168 559.3 0.0 1.4e-85 287.2 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.7 EXF81618.1 - 4.6e-39 133.8 0.0 7.3e-39 133.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Condensation PF00668.15 EXF81618.1 - 2e-37 128.6 0.0 3.2e-37 127.9 0.0 1.4 1 0 0 1 1 1 1 Condensation domain PP-binding PF00550.20 EXF81618.1 - 4.2e-18 65.3 0.0 1.6e-11 44.2 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EXF81618.1 - 3.4e-11 43.9 0.0 4.6e-05 24.2 0.0 3.1 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Epimerase PF01370.16 EXF81618.1 - 4.9e-08 32.6 0.0 1.1e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EXF81618.1 - 0.0014 18.5 2.1 0.023 14.5 0.2 2.7 2 0 0 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EXF81618.1 - 0.073 11.7 0.0 0.53 8.9 0.0 2.1 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MFS_1 PF07690.11 EXF81619.1 - 5.1e-39 133.9 43.5 1e-38 132.9 30.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF81619.1 - 2.2e-09 36.4 11.6 2.2e-09 36.4 8.1 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter Meth_synt_2 PF01717.13 EXF81620.1 - 1.4e-12 47.2 0.0 1.4e-09 37.3 0.0 2.8 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain DUF934 PF06073.7 EXF81620.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF934) Rhodanese PF00581.15 EXF81621.1 - 1.6e-13 50.9 0.0 3.3e-13 49.9 0.0 1.5 1 1 0 1 1 1 1 Rhodanese-like domain Pectate_lyase PF03211.8 EXF81622.1 - 3.5e-67 225.9 3.9 4.3e-67 225.6 2.7 1.0 1 0 0 1 1 1 1 Pectate lyase Acyl-CoA_dh_1 PF00441.19 EXF81623.1 - 5.7e-22 78.4 0.0 1.1e-21 77.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EXF81623.1 - 4.1e-15 56.3 0.0 8.5e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EXF81623.1 - 1.7e-06 27.4 0.3 3.6e-06 26.3 0.2 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EXF81623.1 - 0.0003 21.0 0.0 0.00063 20.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain MFS_1 PF07690.11 EXF81625.1 - 2.8e-24 85.4 63.4 2.1e-23 82.6 27.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OppC_N PF12911.2 EXF81625.1 - 0.14 11.5 0.1 0.14 11.5 0.0 2.7 2 1 1 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C DIT1_PvcA PF05141.7 EXF81626.1 - 1e-76 257.8 0.0 1.6e-76 257.3 0.0 1.3 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein DHO_dh PF01180.16 EXF81627.1 - 1.9e-69 233.9 0.4 8.1e-58 195.7 0.0 2.1 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase Mpv17_PMP22 PF04117.7 EXF81627.1 - 1.5e-16 59.7 0.3 3.1e-16 58.7 0.2 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family PcrB PF01884.12 EXF81627.1 - 0.00027 20.2 1.3 0.23 10.6 0.1 2.3 2 0 0 2 2 2 2 PcrB family FMN_dh PF01070.13 EXF81627.1 - 0.042 12.7 0.4 0.77 8.5 0.2 2.3 2 0 0 2 2 2 0 FMN-dependent dehydrogenase HET PF06985.6 EXF81628.1 - 3.9e-20 72.4 3.9 3.2e-16 59.7 0.4 2.4 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Nuf2 PF03800.9 EXF81632.1 - 3.8e-46 156.6 0.3 1.8e-45 154.5 0.0 2.2 2 0 0 2 2 2 1 Nuf2 family Reo_sigmaC PF04582.7 EXF81632.1 - 1 8.4 12.2 2.3 7.3 4.4 2.3 1 1 1 2 2 2 0 Reovirus sigma C capsid protein MscS_porin PF12795.2 EXF81632.1 - 2 7.6 39.3 4.3 6.5 16.3 3.1 1 1 2 3 3 3 0 Mechanosensitive ion channel porin domain Adaptin_N PF01602.15 EXF81634.1 - 3.9e-107 358.7 0.0 4.7e-107 358.4 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EXF81634.1 - 3.5e-12 46.4 4.4 2.3e-05 24.5 0.0 4.9 4 1 0 4 4 4 3 HEAT repeats HEAT PF02985.17 EXF81634.1 - 3.4e-10 39.1 0.2 0.033 14.2 0.0 6.0 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EXF81634.1 - 1.1e-05 25.7 7.2 0.0048 17.3 0.0 5.2 5 0 0 5 5 5 1 HEAT-like repeat Cohesin_HEAT PF12765.2 EXF81634.1 - 0.0028 17.5 1.0 0.18 11.8 0.0 3.2 3 0 0 3 3 3 1 HEAT repeat associated with sister chromatid cohesion Cnd1 PF12717.2 EXF81634.1 - 0.0071 16.2 0.0 0.17 11.6 0.0 2.7 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 SDA1 PF05285.7 EXF81634.1 - 0.048 12.9 22.7 0.07 12.4 15.8 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.7 EXF81634.1 - 0.083 10.8 30.1 0.11 10.3 20.9 1.2 1 0 0 1 1 1 0 Nop14-like family Pox_Ag35 PF03286.9 EXF81634.1 - 0.93 8.9 12.8 1.8 8.0 8.9 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CobT PF06213.7 EXF81634.1 - 3.5 6.6 27.8 6.1 5.8 19.3 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT BUD22 PF09073.5 EXF81634.1 - 4.6 6.1 22.2 6.4 5.7 15.4 1.2 1 0 0 1 1 1 0 BUD22 CENP-T PF15511.1 EXF81634.1 - 7 5.7 21.3 12 4.9 14.8 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T RTA1 PF04479.8 EXF81635.1 - 2.3e-38 131.9 2.2 3.2e-38 131.4 1.6 1.1 1 0 0 1 1 1 1 RTA1 like protein PGG PF13962.1 EXF81635.1 - 0.0054 16.3 0.3 0.016 14.7 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function DUF2197 PF09963.4 EXF81636.1 - 0.53 10.2 2.6 0.63 10.0 0.2 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) NAD_binding_2 PF03446.10 EXF81637.1 - 4.1e-37 127.5 0.0 6.2e-37 126.9 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EXF81637.1 - 2.6e-31 108.2 0.0 4.3e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EXF81637.1 - 3e-07 30.7 0.9 6.4e-07 29.7 0.0 2.0 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent OCD_Mu_crystall PF02423.10 EXF81637.1 - 1.4e-06 27.2 0.0 2.1e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family TrkA_N PF02254.13 EXF81637.1 - 0.00016 21.6 0.0 0.00029 20.8 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.15 EXF81637.1 - 0.0075 16.3 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.18 EXF81637.1 - 0.0085 15.9 0.1 0.019 14.7 0.1 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EXF81637.1 - 0.024 14.3 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EXF81637.1 - 0.048 13.2 1.0 0.081 12.5 0.1 1.9 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EXF81637.1 - 0.053 14.0 0.0 0.13 12.8 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold MTS PF05175.9 EXF81637.1 - 0.066 12.5 0.1 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain KilA-N PF04383.8 EXF81638.1 - 0.029 14.0 0.0 0.2 11.2 0.0 2.2 1 1 0 1 1 1 0 KilA-N domain PAP1 PF08601.5 EXF81638.1 - 2.2 7.9 8.2 4.2 6.9 5.6 1.4 1 1 0 1 1 1 0 Transcription factor PAP1 Rho_GDI PF02115.12 EXF81639.1 - 1.6e-51 174.5 0.6 4.5e-51 173.1 0.1 1.7 2 0 0 2 2 2 1 RHO protein GDP dissociation inhibitor Metallophos PF00149.23 EXF81640.1 - 2.7e-38 131.3 0.2 4.7e-38 130.5 0.1 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase zf-CCHC PF00098.18 EXF81641.1 - 0.002 17.9 0.7 0.0038 17.0 0.5 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF4171 PF13775.1 EXF81641.1 - 6.5 6.9 13.0 0.69 10.0 5.2 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4171) DUF3129 PF11327.3 EXF81642.1 - 1.5e-69 233.4 14.4 2.8e-69 232.6 10.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3129) TTL PF03133.10 EXF81643.1 - 1.3e-32 112.9 0.0 4.4e-32 111.1 0.0 1.7 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family Dala_Dala_lig_C PF07478.8 EXF81643.1 - 0.021 14.2 0.0 0.04 13.2 0.0 1.4 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ATPgrasp_YheCD PF14398.1 EXF81643.1 - 0.023 13.4 0.0 0.053 12.3 0.0 1.5 1 0 0 1 1 1 0 YheC/D like ATP-grasp HAUS6_N PF14661.1 EXF81644.1 - 5e-55 186.5 4.3 1e-54 185.5 3.0 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus Ribosomal_S21 PF01165.15 EXF81645.1 - 4.9e-13 48.3 7.0 7.2e-13 47.7 4.9 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 PWI PF01480.12 EXF81646.1 - 2.9e-10 40.0 1.3 4.5e-10 39.4 0.3 1.9 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.17 EXF81646.1 - 0.04 13.5 0.0 0.1 12.2 0.0 1.8 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BCL_N PF04714.8 EXF81646.1 - 0.042 13.4 0.4 3.7 7.2 0.0 2.9 2 0 0 2 2 2 0 BCL7, N-terminal conserver region Nuc_sug_transp PF04142.10 EXF81647.1 - 4.5e-40 137.2 2.9 6.3e-40 136.8 2.0 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.6 EXF81647.1 - 3.1e-05 23.0 5.8 3.1e-05 23.0 4.0 1.9 2 1 0 2 2 2 1 UAA transporter family EmrE PF13536.1 EXF81647.1 - 9e-05 22.6 3.3 9e-05 22.6 2.3 2.6 2 1 1 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 EXF81647.1 - 0.0014 18.3 9.7 0.018 14.7 0.6 2.5 2 1 0 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.15 EXF81647.1 - 0.0053 16.7 2.0 0.0053 16.7 1.4 2.9 2 1 0 2 2 2 1 EamA-like transporter family Phage_holin_5 PF06946.6 EXF81647.1 - 0.012 15.7 0.2 0.03 14.4 0.2 1.7 1 0 0 1 1 1 0 Phage holin Glyco_transf_8 PF01501.15 EXF81648.1 - 2.3e-09 36.9 0.4 3.4e-09 36.4 0.3 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 8 MFS_1 PF07690.11 EXF81650.1 - 5.4e-42 143.7 40.9 5.4e-42 143.7 28.4 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF81650.1 - 1.5e-13 50.1 28.8 3.4e-09 35.7 8.3 3.2 2 1 0 2 2 2 2 Sugar (and other) transporter HD_3 PF13023.1 EXF81653.1 - 2.2e-46 157.6 0.0 3.5e-46 156.9 0.0 1.3 1 0 0 1 1 1 1 HD domain GFO_IDH_MocA PF01408.17 EXF81653.1 - 3.9e-25 88.6 0.4 6.9e-25 87.9 0.3 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EXF81653.1 - 5.8e-14 51.8 0.1 2.1e-13 50.0 0.0 2.0 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain Semialdhyde_dh PF01118.19 EXF81653.1 - 0.00031 21.0 0.2 0.00063 20.0 0.1 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Gp_dh_N PF00044.19 EXF81653.1 - 0.029 14.3 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Glyco_hydro_43 PF04616.9 EXF81654.1 - 2.3e-22 79.4 13.0 1.1e-10 41.1 0.2 3.5 3 1 0 3 3 3 3 Glycosyl hydrolases family 43 DIOX_N PF14226.1 EXF81656.1 - 1.6e-20 73.7 0.0 3.1e-20 72.8 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EXF81656.1 - 1.7e-16 60.3 0.0 3e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TRAP_alpha PF03896.11 EXF81656.1 - 0.13 11.2 0.0 0.2 10.6 0.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Fungal_trans_2 PF11951.3 EXF81657.1 - 6.1e-37 127.1 2.0 9.1e-37 126.5 1.4 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lyase_1 PF00206.15 EXF81657.1 - 0.056 12.6 0.1 0.099 11.8 0.1 1.3 1 0 0 1 1 1 0 Lyase Sugar_tr PF00083.19 EXF81658.1 - 8.5e-75 252.0 28.9 1e-74 251.7 20.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF81658.1 - 8.5e-18 64.1 37.9 2.6e-15 56.0 22.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily YtpI PF14007.1 EXF81658.1 - 7.1 6.6 10.0 13 5.8 2.7 2.9 2 0 0 2 2 2 0 YtpI-like protein Transferase PF02458.10 EXF81660.1 - 1.1e-21 76.8 0.0 2e-20 72.6 0.0 2.0 2 0 0 2 2 2 2 Transferase family Fructosamin_kin PF03881.9 EXF81661.1 - 3.1e-28 98.5 0.0 3.8e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 Fructosamine kinase APH PF01636.18 EXF81661.1 - 9.9e-05 22.1 0.2 0.00012 21.9 0.1 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family CCDC155 PF14662.1 EXF81662.1 - 0.042 13.4 0.4 0.047 13.2 0.3 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DNA_topoisoIV PF00521.15 EXF81662.1 - 0.063 12.1 0.0 0.071 11.9 0.0 1.0 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A p450 PF00067.17 EXF81664.1 - 1.4e-40 139.2 0.0 1.9e-40 138.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ORF6C PF10552.4 EXF81664.1 - 0.02 14.5 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 ORF6C domain Methyltransf_23 PF13489.1 EXF81665.1 - 8.6e-06 25.5 0.0 1.2e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF81665.1 - 0.0096 16.3 0.1 0.022 15.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF81665.1 - 0.026 15.0 0.0 0.053 13.9 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain His_Phos_1 PF00300.17 EXF81666.1 - 3.3e-31 108.4 0.0 3.9e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Osmo_CC PF08946.5 EXF81668.1 - 0.018 15.0 0.5 2.9 7.9 0.2 2.2 2 0 0 2 2 2 0 Osmosensory transporter coiled coil UCH PF00443.24 EXF81669.1 - 2.5e-53 180.9 0.0 3.3e-53 180.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EXF81669.1 - 3.1e-19 69.5 0.0 7.3e-19 68.3 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EXF81669.1 - 1.4e-10 40.3 0.9 2.2e-09 36.5 0.1 2.4 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.1 EXF81669.1 - 0.0044 17.2 0.1 0.049 13.8 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-like domain ARPC4 PF05856.7 EXF81670.1 - 2.6e-68 228.7 4.8 2.6e-68 228.7 3.4 1.6 2 0 0 2 2 2 1 ARP2/3 complex 20 kDa subunit (ARPC4) RRM_6 PF14259.1 EXF81671.1 - 2e-07 30.8 0.0 4.2e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF81671.1 - 0.0056 16.4 0.0 0.011 15.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EXF81671.1 - 0.087 12.4 0.0 0.23 11.1 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CRAL_TRIO PF00650.15 EXF81672.1 - 4.6e-12 45.6 0.0 6.6e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EXF81672.1 - 0.011 15.8 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain SET PF00856.23 EXF81673.1 - 3.9e-21 76.0 2.1 1.3e-20 74.3 0.5 2.5 2 0 0 2 2 2 1 SET domain ORC6 PF05460.8 EXF81673.1 - 2.5 7.0 21.5 0.59 9.1 6.4 2.6 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) DUF4482 PF14818.1 EXF81673.1 - 9.1 6.9 7.9 0.58 10.7 0.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4482) DUF2946 PF11162.3 EXF81674.1 - 0.1 12.8 0.3 0.12 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) zf-DHHC PF01529.15 EXF81676.1 - 1.6e-28 99.2 1.0 1.6e-28 99.2 0.7 2.4 1 1 1 2 2 2 1 DHHC palmitoyltransferase IMS PF00817.15 EXF81677.1 - 3.2e-41 140.5 0.0 1.1e-40 138.8 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.3 EXF81677.1 - 8.3e-15 54.8 0.0 1.7e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EXF81677.1 - 0.02 14.9 0.0 0.051 13.6 0.0 1.7 1 0 0 1 1 1 0 IMS family HHH motif RAP1 PF07218.6 EXF81677.1 - 0.33 9.0 0.1 0.5 8.4 0.1 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) IBN_N PF03810.14 EXF81679.1 - 1.3e-16 60.2 4.9 2.5e-13 49.7 0.0 4.6 4 0 0 4 4 4 2 Importin-beta N-terminal domain Cse1 PF08506.5 EXF81679.1 - 3e-09 35.9 0.6 5.1e-08 31.8 0.0 2.8 2 1 1 3 3 3 1 Cse1 Xpo1 PF08389.7 EXF81679.1 - 7.7e-07 29.1 2.0 2.8e-05 24.0 0.1 3.9 4 0 0 4 4 4 1 Exportin 1-like protein HEAT_2 PF13646.1 EXF81679.1 - 6.4e-06 26.3 1.9 0.0022 18.2 0.1 3.5 3 0 0 3 3 3 2 HEAT repeats GRIP PF01465.15 EXF81679.1 - 0.011 15.2 0.0 0.056 12.9 0.0 2.4 1 0 0 1 1 1 0 GRIP domain SRA1 PF07304.6 EXF81681.1 - 0.0085 15.8 0.3 0.0085 15.8 0.2 3.2 3 0 0 3 3 3 1 Steroid receptor RNA activator (SRA1) TT_ORF2 PF02957.10 EXF81682.1 - 0.92 10.2 0.0 0.92 10.2 0.0 3.7 4 0 0 4 4 4 0 TT viral ORF2 ATP-sulfurylase PF01747.12 EXF81683.1 - 1.1e-87 292.9 0.2 1.4e-87 292.5 0.2 1.2 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 EXF81683.1 - 1.3e-56 190.6 0.0 2e-56 189.9 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 EXF81683.1 - 4e-53 179.0 0.0 6.3e-53 178.4 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain TRP PF06011.7 EXF81684.1 - 1.4e-90 303.9 27.3 2.9e-90 302.9 18.9 1.5 1 1 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EXF81684.1 - 5.5e-29 101.0 0.0 8.7e-29 100.3 0.0 1.3 1 0 0 1 1 1 1 ML-like domain SNARE PF05739.14 EXF81688.1 - 4.6e-18 64.6 2.0 2.2e-17 62.4 0.1 2.5 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EXF81688.1 - 3.4e-14 52.8 0.2 3.4e-14 52.8 0.1 2.8 4 0 0 4 4 4 1 Syntaxin MCPsignal PF00015.16 EXF81688.1 - 0.0099 15.4 0.5 0.0099 15.4 0.3 2.2 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Atg14 PF10186.4 EXF81688.1 - 0.01 14.8 4.6 0.06 12.2 0.0 2.8 3 0 0 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Sed5p PF11416.3 EXF81688.1 - 0.024 14.0 0.0 0.056 12.8 0.0 1.6 1 0 0 1 1 1 0 Integral membrane protein Sed5p Syntaxin-18_N PF10496.4 EXF81688.1 - 0.069 12.9 0.8 0.54 10.1 0.0 2.4 2 0 0 2 2 2 0 SNARE-complex protein Syntaxin-18 N-terminus Spc7 PF08317.6 EXF81688.1 - 0.11 11.1 2.6 0.16 10.5 0.5 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein SF-assemblin PF06705.6 EXF81688.1 - 0.14 11.2 7.2 0.52 9.4 0.6 2.8 2 1 1 3 3 3 0 SF-assemblin/beta giardin RGCC PF15151.1 EXF81688.1 - 0.21 12.0 1.2 0.61 10.5 0.1 2.2 2 0 0 2 2 2 0 Response gene to complement 32 protein family NPV_P10 PF05531.7 EXF81688.1 - 0.77 10.0 4.8 12 6.2 0.1 3.4 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Aldo_ket_red PF00248.16 EXF81689.1 - 1.2e-52 178.5 0.0 1.4e-52 178.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.7 EXF81690.1 - 5.9e-27 93.5 0.7 5.9e-27 93.5 0.5 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF81690.1 - 3.2e-16 59.0 0.7 5.7e-16 58.2 0.5 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EXF81690.1 - 0.0026 17.1 0.6 0.0077 15.6 0.3 1.9 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 EXF81690.1 - 0.01 14.3 0.4 0.017 13.6 0.2 1.3 1 0 0 1 1 1 0 HI0933-like protein 3HCDH_N PF02737.13 EXF81690.1 - 0.076 12.6 0.7 0.14 11.8 0.5 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EXF81690.1 - 0.12 11.8 0.2 0.12 11.8 0.1 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain adh_short PF00106.20 EXF81691.1 - 7.2e-29 100.8 1.3 2.5e-28 99.1 0.9 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF81691.1 - 1.6e-17 64.1 0.7 1.9e-16 60.5 0.5 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF81691.1 - 1.4e-14 54.1 0.8 3.7e-14 52.7 0.6 1.7 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF81691.1 - 7.1e-06 25.6 0.3 4.7e-05 22.9 0.2 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EXF81691.1 - 0.0012 18.1 1.8 0.019 14.2 0.3 2.9 3 0 0 3 3 3 1 NmrA-like family Eno-Rase_NADH_b PF12242.3 EXF81691.1 - 0.0022 17.7 0.9 0.0042 16.8 0.6 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1815 PF08844.5 EXF81691.1 - 0.0038 16.8 0.0 0.0068 16.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1815) RmlD_sub_bind PF04321.12 EXF81691.1 - 0.011 14.6 0.1 0.021 13.6 0.0 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_10 PF13460.1 EXF81691.1 - 0.021 14.8 2.7 0.04 13.9 1.0 2.0 2 1 0 2 2 2 0 NADH(P)-binding ApbA PF02558.11 EXF81691.1 - 0.035 13.5 0.1 0.072 12.5 0.1 1.5 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA NAD_binding_7 PF13241.1 EXF81691.1 - 0.12 12.6 0.1 0.28 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Glyco_transf_28 PF03033.15 EXF81691.1 - 0.19 11.5 3.4 4 7.1 0.8 2.9 2 1 0 3 3 3 0 Glycosyltransferase family 28 N-terminal domain DUF1100 PF06500.6 EXF81692.1 - 1.4e-12 46.9 0.0 1.8e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_6 PF12697.2 EXF81692.1 - 1.3e-09 38.2 0.5 2.8e-09 37.1 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF81692.1 - 1.5e-09 37.7 0.0 2.8e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF81692.1 - 8e-06 25.2 0.0 1.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EXF81692.1 - 1.2e-05 24.9 0.1 2e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.15 EXF81692.1 - 0.00011 21.7 0.0 0.0011 18.4 0.0 2.2 1 1 0 1 1 1 1 Putative esterase Esterase_phd PF10503.4 EXF81692.1 - 0.00076 18.7 0.1 0.0025 17.0 0.0 1.8 3 0 0 3 3 3 1 Esterase PHB depolymerase Abhydrolase_3 PF07859.8 EXF81692.1 - 0.056 13.0 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Acetyltransf_1 PF00583.19 EXF81693.1 - 2.4e-10 40.2 0.0 4.2e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF81693.1 - 7.1e-09 35.7 0.1 1e-08 35.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AstA PF04958.7 EXF81693.1 - 0.044 12.2 0.0 0.063 11.6 0.0 1.2 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit Acetyltransf_3 PF13302.1 EXF81693.1 - 0.066 13.3 0.0 0.077 13.1 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EXF81693.1 - 0.069 13.0 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Lipase_3 PF01764.20 EXF81694.1 - 1.8e-13 50.2 0.0 1.1e-12 47.7 0.0 2.1 1 1 0 1 1 1 1 Lipase (class 3) DPBB_1 PF03330.13 EXF81695.1 - 3.4e-09 36.5 0.0 3.4e-09 36.5 0.0 2.5 4 0 0 4 4 4 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EXF81695.1 - 3.8e-07 29.7 0.2 8.2e-07 28.7 0.1 1.5 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.7 EXF81695.1 - 0.00081 19.3 0.2 0.0018 18.2 0.1 1.6 1 0 0 1 1 1 1 Cerato-platanin Pollen_allerg_1 PF01357.16 EXF81695.1 - 0.0043 16.8 0.5 0.0099 15.6 0.4 1.6 1 0 0 1 1 1 1 Pollen allergen BNR PF02012.15 EXF81695.1 - 0.022 14.5 0.3 0.076 12.8 0.2 2.0 1 0 0 1 1 1 0 BNR/Asp-box repeat Mo-co_dimer PF03404.11 EXF81695.1 - 0.043 13.4 0.0 0.12 12.0 0.0 1.6 1 1 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain C2 PF00168.25 EXF81696.1 - 3.3e-71 235.1 3.5 4.9e-22 77.5 0.1 5.6 5 0 0 5 5 5 5 C2 domain FKBP_C PF00254.23 EXF81696.1 - 0.056 13.4 0.0 0.27 11.2 0.0 2.2 1 0 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2404 PF10296.4 EXF81696.1 - 0.12 12.4 0.0 0.38 10.8 0.0 1.8 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) WD40 PF00400.27 EXF81697.1 - 2.7e-49 163.3 15.5 1.8e-10 40.2 0.1 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat PRP4 PF08799.6 EXF81697.1 - 2.9e-13 48.8 3.5 5.3e-13 47.9 2.5 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Nbas_N PF15492.1 EXF81697.1 - 0.0073 15.4 0.0 0.54 9.2 0.0 2.3 2 0 0 2 2 2 2 Neuroblastoma-amplified sequence, N terminal Beta_elim_lyase PF01212.16 EXF81698.1 - 3.5e-62 210.1 0.1 4.3e-62 209.8 0.1 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EXF81698.1 - 7.3e-05 21.9 1.8 0.0002 20.5 0.2 1.9 2 0 0 2 2 2 1 DegT/DnrJ/EryC1/StrS aminotransferase family MFS_1 PF07690.11 EXF81699.1 - 2e-27 95.8 16.0 2.9e-27 95.3 11.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF81699.1 - 7.3e-14 51.1 11.2 1.5e-13 50.1 7.8 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter DOMON PF03351.12 EXF81701.1 - 2.3e-08 34.0 0.4 5.8e-08 32.7 0.3 1.6 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.11 EXF81701.1 - 6.3e-06 26.0 12.7 1.3e-05 25.0 8.8 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 EXF81701.1 - 0.0023 17.4 8.1 0.0023 17.4 5.6 2.5 1 1 1 2 2 2 1 Domain of unknown function (DUF2427) DUF2306 PF10067.4 EXF81701.1 - 0.013 15.6 3.2 0.013 15.6 2.3 3.3 1 1 2 3 3 3 0 Predicted membrane protein (DUF2306) FTR_C PF02741.10 EXF81701.1 - 0.043 13.5 1.1 0.092 12.5 0.7 1.5 1 0 0 1 1 1 0 FTR, proximal lobe Serglycin PF04360.7 EXF81701.1 - 0.45 10.2 13.9 0.45 10.2 8.1 2.1 1 1 0 1 1 1 0 Serglycin ATP_sub_h PF10775.4 EXF81702.1 - 8.6e-26 89.4 0.5 1.3e-25 88.8 0.3 1.3 1 0 0 1 1 1 1 ATP synthase complex subunit h ATP-synt_F6 PF05511.6 EXF81702.1 - 0.014 15.2 0.1 0.021 14.7 0.1 1.4 1 1 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 C2 PF00168.25 EXF81703.1 - 2e-06 27.5 0.1 1.1e-05 25.1 0.1 2.1 1 1 0 1 1 1 1 C2 domain Pkinase_C PF00433.19 EXF81703.1 - 0.0068 16.9 5.2 0.079 13.4 0.2 3.7 3 1 0 3 3 3 1 Protein kinase C terminal domain ASXH PF13919.1 EXF81706.1 - 0.049 13.4 0.0 0.053 13.3 0.0 1.2 1 0 0 1 1 1 0 Asx homology domain SUZ PF12752.2 EXF81707.1 - 0.0012 19.3 5.5 0.0012 19.3 3.8 3.4 2 2 0 2 2 2 1 SUZ domain DUF1754 PF08555.5 EXF81707.1 - 0.018 15.6 2.0 5.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic family of unknown function (DUF1754) CRF PF00473.12 EXF81707.1 - 0.085 12.9 4.3 0.1 12.7 0.1 2.3 2 0 0 2 2 2 0 Corticotropin-releasing factor family Sua5_yciO_yrdC PF01300.13 EXF81707.1 - 0.17 11.1 0.1 0.25 10.5 0.1 1.2 1 0 0 1 1 1 0 Telomere recombination API5 PF05918.6 EXF81707.1 - 4.6 5.6 10.9 5.9 5.2 7.6 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) Fe_hyd_lg_C PF02906.9 EXF81708.1 - 1.3e-58 198.5 0.0 3.8e-58 197.0 0.0 1.7 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain PhoD PF09423.5 EXF81711.1 - 3.1e-60 204.0 0.0 3.5e-60 203.8 0.0 1.1 1 0 0 1 1 1 1 PhoD-like phosphatase EMP24_GP25L PF01105.19 EXF81712.1 - 4.5e-44 150.3 1.2 4.5e-44 150.3 0.8 3.5 3 0 0 3 3 3 2 emp24/gp25L/p24 family/GOLD Chromo PF00385.19 EXF81712.1 - 0.014 15.1 0.3 0.036 13.7 0.2 1.8 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Myosin_tail_1 PF01576.14 EXF81712.1 - 0.024 12.3 41.5 0.044 11.5 28.8 1.3 1 0 0 1 1 1 0 Myosin tail Tropomyosin PF00261.15 EXF81712.1 - 0.056 12.5 41.5 0.14 11.2 28.8 1.6 1 0 0 1 1 1 0 Tropomyosin FlaC_arch PF05377.6 EXF81712.1 - 0.86 9.5 8.4 3.8 7.4 2.1 3.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DUF489 PF04356.7 EXF81712.1 - 1.6 8.2 10.3 6.4 6.3 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF489) V_ATPase_I PF01496.14 EXF81712.1 - 5.1 4.8 22.1 8.4 4.1 15.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family COX5A PF02284.11 EXF81713.1 - 2.3e-40 136.8 0.4 3.2e-40 136.4 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Va ELO PF01151.13 EXF81714.1 - 2.9e-63 213.5 15.3 3.4e-63 213.2 10.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF4149 PF13664.1 EXF81714.1 - 0.033 14.2 2.1 0.22 11.5 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) Porphobil_deam PF01379.15 EXF81716.1 - 3e-77 258.3 0.0 4.2e-77 257.9 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EXF81716.1 - 6e-18 64.7 0.2 1.1e-17 63.8 0.2 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain GCV_H PF01597.14 EXF81717.1 - 3.4e-36 123.6 2.0 4.1e-36 123.3 1.4 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 EXF81717.1 - 0.021 14.4 1.0 0.029 13.9 0.2 1.7 2 0 0 2 2 2 0 Biotin-requiring enzyme RnfC_N PF13375.1 EXF81717.1 - 0.083 12.6 0.1 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Ras PF00071.17 EXF81718.1 - 9.2e-32 109.6 0.1 1.2e-31 109.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EXF81718.1 - 3.7e-21 75.8 0.1 2.1e-20 73.3 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EXF81718.1 - 1e-06 28.0 0.0 1.3e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EXF81718.1 - 4.5e-05 22.7 0.1 5.8e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EXF81718.1 - 0.053 13.4 0.0 0.095 12.6 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase DLIC PF05783.6 EXF81718.1 - 0.055 12.1 0.1 3.8 6.0 0.0 2.1 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) G-alpha PF00503.15 EXF81718.1 - 0.088 11.4 1.6 0.2 10.2 0.0 2.1 1 1 1 3 3 3 0 G-protein alpha subunit PNTB PF02233.11 EXF81719.1 - 9.7e-170 565.2 27.9 9.7e-170 565.2 19.3 1.8 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EXF81719.1 - 3.6e-54 182.8 0.3 6.5e-54 181.9 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EXF81719.1 - 1e-48 164.7 0.0 2.5e-48 163.5 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EXF81719.1 - 2e-31 108.0 2.9 2e-31 108.0 2.0 5.4 5 2 1 7 7 6 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 EXF81719.1 - 0.00048 19.3 0.1 0.96 8.5 0.0 2.5 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EXF81719.1 - 0.0051 16.3 0.2 0.022 14.3 0.1 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 EXF81719.1 - 0.017 15.0 0.8 0.059 13.2 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Fumerase PF05681.9 EXF81719.1 - 0.023 13.8 0.1 0.041 12.9 0.1 1.3 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) NAD_binding_8 PF13450.1 EXF81719.1 - 0.048 13.6 3.1 0.49 10.4 1.3 3.4 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain Methyltransf_18 PF12847.2 EXF81719.1 - 0.1 13.2 0.0 0.26 11.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EXF81719.1 - 0.14 11.7 0.0 0.34 10.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Shikimate_DH PF01488.15 EXF81719.1 - 0.37 10.8 3.6 9.9 6.2 0.0 3.3 3 1 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Fungal_trans PF04082.13 EXF81720.1 - 1.1e-11 44.1 0.0 2.2e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF81720.1 - 2.4e-08 33.7 11.5 2.4e-08 33.7 8.0 1.9 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Jun PF03957.8 EXF81720.1 - 0.008 15.9 2.3 0.008 15.9 1.6 1.9 2 0 0 2 2 2 1 Jun-like transcription factor DUF4175 PF13779.1 EXF81720.1 - 0.42 8.2 7.9 0.8 7.3 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ABC_membrane PF00664.18 EXF81721.1 - 8.1e-77 258.3 38.3 2.2e-38 132.2 9.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EXF81721.1 - 3.3e-70 234.7 0.0 1.3e-34 119.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EXF81721.1 - 8.1e-14 51.3 2.6 0.00011 21.5 0.0 4.2 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EXF81721.1 - 3.7e-12 46.8 0.0 0.15 12.0 0.0 4.3 3 1 0 4 4 4 4 AAA domain AAA_29 PF13555.1 EXF81721.1 - 9.8e-10 37.8 0.2 0.00051 19.5 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.4 EXF81721.1 - 1.1e-09 37.4 0.6 0.0084 14.7 0.0 4.0 4 0 0 4 4 4 2 Predicted ATPase of the ABC class DUF258 PF03193.11 EXF81721.1 - 1.8e-08 33.7 0.0 0.0014 17.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EXF81721.1 - 4.9e-08 33.1 0.8 0.0026 17.8 0.0 3.9 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EXF81721.1 - 6.9e-07 29.4 4.6 0.00016 21.7 0.2 2.9 2 1 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.7 EXF81721.1 - 2e-06 27.0 1.2 0.02 13.9 0.0 3.8 4 0 0 4 4 4 2 Zeta toxin AAA_25 PF13481.1 EXF81721.1 - 1.4e-05 24.5 0.7 0.16 11.3 0.0 3.2 4 0 0 4 4 3 2 AAA domain AAA_17 PF13207.1 EXF81721.1 - 2.1e-05 25.2 0.0 0.12 13.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EXF81721.1 - 4.2e-05 23.4 0.0 0.11 12.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.1 EXF81721.1 - 0.00015 21.3 2.3 0.47 9.9 0.1 4.2 3 1 0 3 3 3 1 AAA domain G-alpha PF00503.15 EXF81721.1 - 0.00035 19.3 0.0 0.43 9.2 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit AAA_14 PF13173.1 EXF81721.1 - 0.00036 20.4 0.0 1.8 8.4 0.0 4.0 4 0 0 4 4 4 1 AAA domain SbcCD_C PF13558.1 EXF81721.1 - 0.00058 19.7 1.0 0.78 9.7 0.1 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit APS_kinase PF01583.15 EXF81721.1 - 0.00076 19.1 0.1 2.2 7.9 0.0 3.0 3 0 0 3 3 3 2 Adenylylsulphate kinase AAA_19 PF13245.1 EXF81721.1 - 0.0017 18.0 0.1 1.1 9.0 0.0 3.5 2 0 0 2 2 2 1 Part of AAA domain AAA_5 PF07728.9 EXF81721.1 - 0.0021 17.7 0.3 5.1 6.8 0.0 3.7 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.1 EXF81721.1 - 0.003 16.6 0.0 0.48 9.4 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.1 EXF81721.1 - 0.0031 17.8 0.0 1.3 9.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain RrnaAD PF00398.15 EXF81721.1 - 0.0076 15.2 0.0 0.024 13.6 0.0 1.7 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase MobB PF03205.9 EXF81721.1 - 0.011 15.5 0.1 7 6.3 0.0 2.7 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EXF81721.1 - 0.02 14.8 0.1 5.7 6.9 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Miro PF08477.8 EXF81721.1 - 0.025 15.0 0.6 15 6.1 0.0 3.8 5 0 0 5 5 3 0 Miro-like protein AAA PF00004.24 EXF81721.1 - 0.03 14.5 2.0 4 7.6 0.2 4.0 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EXF81721.1 - 0.032 13.6 3.7 9.1 5.6 0.1 4.1 4 0 0 4 4 4 0 AAA-like domain PRK PF00485.13 EXF81721.1 - 0.035 13.6 0.0 5.6 6.4 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ATP-synt_ab PF00006.20 EXF81721.1 - 0.038 13.4 0.0 1.6 8.1 0.0 2.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain DUF87 PF01935.12 EXF81721.1 - 0.041 13.6 1.1 2.6 7.7 0.3 2.7 3 0 0 3 3 2 0 Domain of unknown function DUF87 AAA_18 PF13238.1 EXF81721.1 - 0.046 14.0 0.0 12 6.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.17 EXF81721.1 - 0.048 12.5 0.1 2.3 7.0 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain VirE PF05272.6 EXF81721.1 - 0.054 12.9 0.0 3.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Virulence-associated protein E Rad17 PF03215.10 EXF81721.1 - 0.057 12.1 0.0 0.16 10.6 0.0 1.6 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein DUF815 PF05673.8 EXF81721.1 - 0.059 12.2 0.0 3.9 6.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) RNA_helicase PF00910.17 EXF81721.1 - 0.14 12.3 0.2 6.1 7.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.1 EXF81721.1 - 0.96 9.3 6.3 0.75 9.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain Alk_phosphatase PF00245.15 EXF81722.1 - 2.6e-68 230.6 0.1 5.6e-68 229.5 0.1 1.5 2 0 0 2 2 2 1 Alkaline phosphatase Phosphodiest PF01663.17 EXF81722.1 - 1.2e-07 31.3 0.0 2e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EXF81722.1 - 2.8e-07 30.0 0.0 4.6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Sulfatase DUF229 PF02995.12 EXF81722.1 - 9.1e-05 21.0 0.4 0.00016 20.2 0.1 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF229) DUF1501 PF07394.7 EXF81722.1 - 0.013 14.3 0.1 0.021 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) FTA4 PF13093.1 EXF81722.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 CutC PF03932.9 EXF81723.1 - 5.4e-34 117.2 0.0 8.3e-34 116.6 0.0 1.3 1 0 0 1 1 1 1 CutC family PGP_phosphatase PF09419.5 EXF81724.1 - 1.5e-64 216.3 0.0 1.7e-64 216.1 0.0 1.0 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EXF81724.1 - 4e-05 23.2 0.0 0.00012 21.6 0.0 2.0 1 1 0 1 1 1 1 HAD-hyrolase-like MTHFR PF02219.12 EXF81724.1 - 0.0021 17.2 0.0 0.0027 16.8 0.0 1.1 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase ORC2 PF04084.9 EXF81725.1 - 3.7e-95 318.4 0.0 4.6e-95 318.1 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Elong_Iki1 PF10483.4 EXF81725.1 - 0.0042 16.4 5.0 0.48 9.7 0.2 2.5 2 0 0 2 2 2 2 Elongator subunit Iki1 TRAP_alpha PF03896.11 EXF81725.1 - 0.51 9.2 1.9 1.1 8.2 1.3 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CTP_transf_1 PF01148.15 EXF81726.1 - 2.5e-06 27.3 10.4 2.5e-06 27.3 7.2 3.0 3 1 0 3 3 3 1 Cytidylyltransferase family DUF1754 PF08555.5 EXF81728.1 - 5.9e-07 29.9 27.7 0.00038 21.0 6.0 2.2 1 1 1 2 2 2 2 Eukaryotic family of unknown function (DUF1754) Adaptin_binding PF10199.4 EXF81728.1 - 0.039 14.2 13.3 0.054 13.7 9.2 1.2 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 CDC45 PF02724.9 EXF81728.1 - 0.56 8.1 18.0 0.65 7.9 12.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.7 EXF81728.1 - 0.59 7.9 17.1 0.65 7.8 11.8 1.0 1 0 0 1 1 1 0 Nop14-like family BTV_NS2 PF04514.7 EXF81728.1 - 1.8 7.3 10.8 2.3 6.9 7.5 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 FLO_LFY PF01698.11 EXF81728.1 - 5.3 5.7 11.9 6.9 5.4 8.2 1.2 1 0 0 1 1 1 0 Floricaula / Leafy protein Sigma70_ner PF04546.8 EXF81728.1 - 5.6 6.5 18.5 41 3.6 12.8 1.9 1 1 0 1 1 1 0 Sigma-70, non-essential region DUF3245 PF11595.3 EXF81728.1 - 7.9 6.7 22.5 16 5.7 15.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3245) HGTP_anticodon2 PF12745.2 EXF81728.1 - 8 5.5 10.0 11 5.0 6.9 1.3 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs RRN3 PF05327.6 EXF81728.1 - 8.5 4.3 8.4 9.9 4.1 5.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 UPF0560 PF10577.4 EXF81728.1 - 9.9 4.2 11.4 12 4.0 7.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 AA_permease_2 PF13520.1 EXF81729.1 - 7.8e-62 209.1 41.6 1.1e-61 208.6 28.8 1.2 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF81729.1 - 9.5e-32 109.9 28.8 9.5e-32 109.9 20.0 2.1 2 1 0 2 2 2 1 Amino acid permease DUF4405 PF14358.1 EXF81729.1 - 0.19 11.8 0.1 0.19 11.8 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) 2-Hacid_dh_C PF02826.14 EXF81730.1 - 6e-52 175.3 0.0 9.8e-52 174.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EXF81730.1 - 2.6e-15 56.0 0.0 3.9e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EXF81730.1 - 3.6e-05 23.6 0.0 8.1e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase RicinB_lectin_2 PF14200.1 EXF81734.1 - 0.00099 19.4 1.7 0.0027 18.0 0.3 2.1 1 1 1 2 2 2 2 Ricin-type beta-trefoil lectin domain-like SKG6 PF08693.5 EXF81734.1 - 0.0015 17.8 4.2 0.0049 16.1 2.9 1.9 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Mucin PF01456.12 EXF81734.1 - 0.0025 17.6 18.0 0.0025 17.6 12.5 3.0 3 0 0 3 3 3 1 Mucin-like glycoprotein Rifin_STEVOR PF02009.11 EXF81734.1 - 0.19 11.3 0.1 0.25 10.9 0.1 1.2 1 0 0 1 1 1 0 Rifin/stevor family 4HBT_3 PF13622.1 EXF81737.1 - 0.17 11.6 0.4 0.16 11.6 0.3 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily Mito_fiss_reg PF05308.6 EXF81737.1 - 1.2 8.4 6.6 1.5 8.1 4.6 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator DAO PF01266.19 EXF81738.1 - 7.6e-46 156.6 0.1 1.1e-45 156.1 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EXF81738.1 - 2e-08 33.7 0.2 1.7e-05 24.1 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF81738.1 - 9.9e-08 31.2 1.8 0.0057 15.5 0.8 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EXF81738.1 - 0.00076 19.4 0.1 0.0022 17.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF81738.1 - 0.0058 16.6 0.2 0.15 12.0 0.1 2.9 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.13 EXF81738.1 - 0.0066 16.1 0.1 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EXF81738.1 - 0.036 12.9 0.1 0.17 10.7 0.1 1.9 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.9 EXF81738.1 - 0.044 12.2 0.2 0.067 11.6 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.22 EXF81738.1 - 0.047 14.0 0.2 0.14 12.5 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.1 EXF81738.1 - 0.1 12.5 1.4 0.39 10.6 0.1 2.6 3 1 0 3 3 3 0 NADH(P)-binding Thi4 PF01946.12 EXF81738.1 - 0.14 11.2 1.1 0.95 8.5 0.0 2.5 3 0 0 3 3 3 0 Thi4 family MIP PF00230.15 EXF81739.1 - 2.4e-52 177.6 8.2 2.9e-52 177.4 5.7 1.0 1 0 0 1 1 1 1 Major intrinsic protein FGGY_C PF02782.11 EXF81740.1 - 2.9e-72 242.4 0.9 4.9e-72 241.7 0.6 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EXF81740.1 - 2.8e-66 223.3 0.0 3.6e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain HTH_IclR PF09339.5 EXF81740.1 - 0.03 13.9 0.1 0.23 11.0 0.0 2.4 2 0 0 2 2 2 0 IclR helix-turn-helix domain BcrAD_BadFG PF01869.15 EXF81740.1 - 0.079 12.2 0.2 1.4 8.1 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Fungal_trans PF04082.13 EXF81742.1 - 1.2e-18 66.9 0.2 1.9e-18 66.3 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF81742.1 - 2.8e-08 33.5 11.2 5.5e-08 32.5 7.1 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Gelsolin PF00626.17 EXF81743.1 - 2.7e-34 116.6 0.3 3.3e-12 45.8 0.0 3.3 3 0 0 3 3 3 3 Gelsolin repeat Cu-oxidase_2 PF07731.9 EXF81747.1 - 1.7e-27 95.5 5.9 1.4e-25 89.3 1.6 2.7 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EXF81747.1 - 2.9e-21 75.3 0.8 1e-20 73.6 0.1 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EXF81747.1 - 3.5e-07 30.2 0.2 1.8e-05 24.7 0.0 3.3 4 0 0 4 4 4 1 Multicopper oxidase BORA_N PF15280.1 EXF81747.1 - 0.048 13.0 7.6 0.084 12.2 5.3 1.3 1 0 0 1 1 1 0 Protein aurora borealis N-terminus 2C_adapt PF08793.5 EXF81747.1 - 0.072 12.9 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 2-cysteine adaptor domain Ank_2 PF12796.2 EXF81749.1 - 2e-20 72.9 0.1 1.8e-09 37.8 0.0 5.1 1 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EXF81749.1 - 2.9e-18 64.6 4.7 7e-05 22.4 0.0 7.8 8 0 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.1 EXF81749.1 - 1.6e-16 58.7 0.5 0.041 14.1 0.0 7.9 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.1 EXF81749.1 - 5.3e-15 55.4 2.0 3.7e-05 24.1 0.0 5.4 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF81749.1 - 2.5e-12 46.5 4.7 0.00044 20.4 0.0 6.9 4 2 3 7 7 7 2 Ankyrin repeats (many copies) ZZ PF00569.12 EXF81749.1 - 8.2e-06 25.2 7.9 1.7e-05 24.2 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type DIOX_N PF14226.1 EXF81750.1 - 2.2e-20 73.3 0.0 5.9e-20 71.9 0.0 1.7 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EXF81750.1 - 2.7e-12 46.8 0.0 4.1e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EXF81751.1 - 1e-20 73.7 29.2 1e-20 73.7 20.2 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EXF81752.1 - 2.3e-32 112.0 31.7 2.3e-32 112.0 22.0 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF81752.1 - 1.4e-09 37.1 28.2 3.7e-09 35.6 19.5 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.3 EXF81752.1 - 4.6e-08 31.9 8.8 4.6e-08 31.9 6.1 2.6 1 1 1 2 2 2 1 Vacuole effluxer Atg22 like TRI12 PF06609.8 EXF81752.1 - 8.4e-05 20.9 1.3 0.00013 20.2 0.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Abhydrolase_6 PF12697.2 EXF81754.1 - 1.6e-20 73.9 0.8 2e-20 73.6 0.6 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF81754.1 - 3.7e-11 42.9 1.1 6e-11 42.2 0.8 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF81754.1 - 6.2e-06 25.9 0.1 0.00095 18.7 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 EXF81754.1 - 0.015 14.8 0.4 0.027 13.9 0.2 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase PGAP1 PF07819.8 EXF81754.1 - 0.06 12.9 0.0 0.088 12.3 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Thioesterase PF00975.15 EXF81754.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Epimerase PF01370.16 EXF81755.1 - 6.1e-12 45.4 0.0 3e-11 43.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EXF81755.1 - 9.8e-11 40.8 0.0 1.6e-10 40.1 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EXF81755.1 - 4.2e-09 36.6 0.5 3.1e-08 33.8 0.4 2.3 2 1 0 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EXF81755.1 - 3.2e-06 26.2 0.0 2.7e-05 23.2 0.0 2.1 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EXF81755.1 - 4.5e-05 23.4 0.5 0.00015 21.7 0.2 1.8 2 0 0 2 2 2 1 short chain dehydrogenase NmrA PF05368.8 EXF81755.1 - 0.00047 19.4 0.0 0.0014 17.9 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.12 EXF81755.1 - 0.066 12.0 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain ApbA PF02558.11 EXF81755.1 - 0.15 11.4 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Aldedh PF00171.17 EXF81756.1 - 1.1e-126 422.8 0.0 1.4e-126 422.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EXF81756.1 - 6.3e-06 25.1 1.9 4.9e-05 22.2 1.3 2.0 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) Ald_Xan_dh_C2 PF02738.13 EXF81757.1 - 8.6e-192 638.2 0.0 1.2e-191 637.8 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EXF81757.1 - 5.8e-49 165.7 0.0 1.2e-48 164.7 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.17 EXF81757.1 - 2e-33 114.7 0.1 4e-33 113.8 0.1 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain CO_deh_flav_C PF03450.12 EXF81757.1 - 1.5e-30 105.1 0.9 5.7e-30 103.3 0.1 2.4 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2_2 PF01799.15 EXF81757.1 - 3.5e-29 100.5 0.0 7e-29 99.5 0.0 1.5 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 EXF81757.1 - 6.4e-08 32.2 0.1 6.4e-08 32.2 0.1 2.3 3 0 0 3 3 3 1 2Fe-2S iron-sulfur cluster binding domain PAS PF00989.19 EXF81758.1 - 0.051 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 PAS fold SPO22 PF08631.5 EXF81759.1 - 3.6e-59 200.1 0.2 1.6e-55 188.1 0.0 3.6 3 1 0 3 3 3 3 Meiosis protein SPO22/ZIP4 like Pyridoxal_deC PF00282.14 EXF81760.1 - 2e-73 247.0 0.0 2.6e-73 246.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF3464 PF11947.3 EXF81760.1 - 0.07 12.5 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Ufd2P_core PF10408.4 EXF81761.1 - 6.2e-191 635.8 9.9 7.7e-191 635.5 6.9 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EXF81761.1 - 9.1e-26 89.6 1.1 3e-25 87.9 0.7 2.0 1 0 0 1 1 1 1 U-box domain zf-TRAF PF02176.13 EXF81762.1 - 1.4e-10 41.3 23.0 6.3e-09 36.0 5.1 4.1 2 1 3 5 5 4 4 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 EXF81762.1 - 1.7e-07 31.1 9.7 1.7e-07 31.1 6.7 3.8 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EXF81762.1 - 6.9e-07 28.8 4.9 6.9e-07 28.8 3.4 3.5 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EXF81762.1 - 1.1e-06 28.3 9.0 1.1e-06 28.3 6.2 3.6 2 1 1 3 3 2 1 Ring finger domain zf-RING_5 PF14634.1 EXF81762.1 - 6e-06 25.8 6.6 6e-06 25.8 4.6 3.3 2 2 0 2 2 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EXF81762.1 - 1e-05 25.0 10.1 1e-05 25.0 7.0 3.3 2 1 1 3 3 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EXF81762.1 - 0.00067 19.3 7.9 0.0026 17.4 5.5 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EXF81762.1 - 0.0048 16.7 9.3 0.0048 16.7 6.5 2.6 2 1 1 3 3 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EXF81762.1 - 0.0055 16.7 5.0 0.0055 16.7 3.5 3.8 2 2 1 3 3 2 1 RING-H2 zinc finger Sina PF03145.11 EXF81762.1 - 0.0059 16.2 17.3 0.021 14.5 0.3 3.6 3 1 1 4 4 4 2 Seven in absentia protein family U-box PF04564.10 EXF81762.1 - 0.013 15.4 0.6 0.07 13.0 0.3 2.3 2 0 0 2 2 2 0 U-box domain DivIC PF04977.10 EXF81762.1 - 0.19 11.2 3.3 0.62 9.5 1.2 2.2 2 0 0 2 2 2 0 Septum formation initiator zf-P11 PF03854.9 EXF81762.1 - 0.43 10.0 11.6 0.37 10.2 2.0 2.8 1 1 1 2 2 2 0 P-11 zinc finger XhlA PF10779.4 EXF81762.1 - 0.59 10.0 4.4 5.6 6.9 0.7 2.3 2 0 0 2 2 2 0 Haemolysin XhlA IncA PF04156.9 EXF81762.1 - 1.5 8.3 4.3 3.1 7.3 3.0 1.5 1 1 0 1 1 1 0 IncA protein Pyr_redox_3 PF13738.1 EXF81763.1 - 3.8e-23 82.6 0.0 1.1e-22 81.1 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EXF81763.1 - 7.4e-11 40.9 0.0 1.1e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EXF81763.1 - 2.2e-06 27.6 0.2 9.6e-06 25.6 0.1 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF81763.1 - 3e-06 26.4 0.0 8.6e-06 24.8 0.0 1.7 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.22 EXF81763.1 - 5.8e-05 23.4 0.1 0.4 11.1 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EXF81763.1 - 0.0014 17.7 0.1 0.0035 16.4 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EXF81763.1 - 0.0016 18.4 0.1 0.0055 16.7 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain CPSase_L_chain PF00289.17 EXF81763.1 - 0.0026 17.8 0.1 0.87 9.7 0.0 2.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain 2-Hacid_dh_C PF02826.14 EXF81763.1 - 0.0076 15.4 0.0 0.3 10.2 0.0 2.3 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.9 EXF81763.1 - 0.011 14.2 1.2 0.5 8.7 0.1 2.8 3 0 0 3 3 3 0 HI0933-like protein Lycopene_cycl PF05834.7 EXF81763.1 - 0.014 14.3 0.0 0.11 11.4 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein F420_oxidored PF03807.12 EXF81763.1 - 0.041 14.3 0.0 1e+02 3.3 0.0 3.4 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_9 PF13454.1 EXF81763.1 - 0.065 12.9 0.4 5.4 6.7 0.0 2.9 3 0 0 3 3 3 0 FAD-NAD(P)-binding PS_pyruv_trans PF04230.8 EXF81763.1 - 0.083 12.5 0.0 0.28 10.8 0.0 1.8 2 0 0 2 2 2 0 Polysaccharide pyruvyl transferase DAO PF01266.19 EXF81763.1 - 0.092 11.6 2.2 2.4 7.0 0.1 3.1 3 1 0 3 3 3 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EXF81763.1 - 0.11 12.0 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AAA PF00004.24 EXF81764.1 - 1.2e-16 61.1 0.0 2e-16 60.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EXF81764.1 - 0.022 14.9 0.0 0.049 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Transp_cyt_pur PF02133.10 EXF81765.1 - 9.3e-99 330.9 34.5 1.2e-98 330.5 23.9 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin Fungal_trans PF04082.13 EXF81765.1 - 4.4e-24 84.7 0.3 8e-24 83.9 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF917 PF06032.7 EXF81766.1 - 2.6e-116 388.0 0.0 4.1e-116 387.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EXF81766.1 - 3.1e-47 161.0 8.9 8.3e-46 156.3 3.3 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EXF81766.1 - 6.3e-31 107.2 2.3 2.6e-27 95.4 0.0 3.4 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region MutL PF13941.1 EXF81766.1 - 5.7e-05 21.6 3.8 0.059 11.6 0.0 3.2 3 0 0 3 3 3 2 MutL protein StbA PF06406.6 EXF81766.1 - 0.00013 20.9 0.6 0.15 10.9 0.0 2.4 2 0 0 2 2 2 2 StbA protein BcrAD_BadFG PF01869.15 EXF81766.1 - 0.0034 16.7 4.1 0.6 9.3 0.4 2.6 2 1 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family DUF3663 PF12404.3 EXF81766.1 - 0.095 12.4 0.0 0.21 11.4 0.0 1.5 1 0 0 1 1 1 0 Peptidase Jacalin PF01419.12 EXF81769.1 - 1.4e-05 24.9 0.0 0.00038 20.3 0.0 2.2 2 0 0 2 2 2 1 Jacalin-like lectin domain F-box PF00646.28 EXF81769.1 - 0.00047 19.7 0.2 0.0011 18.5 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EXF81769.1 - 0.024 14.3 2.1 0.028 14.1 0.4 1.9 2 0 0 2 2 2 0 F-box-like 2OG-FeII_Oxy_3 PF13640.1 EXF81770.1 - 0.00011 22.6 0.5 0.00035 21.0 0.2 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EXF81770.1 - 0.00094 19.4 0.1 0.0021 18.3 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily adh_short PF00106.20 EXF81771.1 - 8.3e-15 55.0 0.0 1.4e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF81771.1 - 3.1e-07 30.2 0.0 4.5e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF81771.1 - 0.0011 18.8 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Cofilin_ADF PF00241.15 EXF81772.1 - 2e-13 50.3 0.1 2.4e-13 50.0 0.1 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein MFS_1 PF07690.11 EXF81778.1 - 5.2e-42 143.8 29.9 5.2e-42 143.8 20.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF81778.1 - 7.3e-15 54.4 7.9 7.3e-15 54.4 5.5 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EXF81778.1 - 7.9e-10 37.5 2.7 1.3e-09 36.8 1.8 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EXF81778.1 - 9.7e-06 24.2 2.0 9.7e-06 24.2 1.4 3.1 3 1 1 4 4 4 2 MFS/sugar transport protein MFS_1_like PF12832.2 EXF81778.1 - 0.00054 19.7 1.5 0.033 13.9 0.0 3.3 3 0 0 3 3 3 1 MFS_1 like family MFS_1 PF07690.11 EXF81779.1 - 2.2e-29 102.3 29.1 3.3e-29 101.7 20.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily p450 PF00067.17 EXF81780.1 - 1.2e-63 215.3 0.0 1.4e-63 215.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Band_7 PF01145.20 EXF81781.1 - 2.9e-12 46.8 0.2 2.9e-12 46.8 0.1 3.5 2 2 0 2 2 2 1 SPFH domain / Band 7 family CFEM PF05730.6 EXF81782.1 - 3.9e-15 55.4 8.7 6.2e-15 54.7 6.1 1.3 1 0 0 1 1 1 1 CFEM domain adh_short PF00106.20 EXF81782.1 - 1.3e-06 28.4 0.1 2.4e-06 27.5 0.1 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF81782.1 - 9.8e-05 22.0 0.0 0.00022 20.9 0.0 1.5 1 0 0 1 1 1 1 KR domain TPR_11 PF13414.1 EXF81782.1 - 0.1 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 TPR repeat DUF258 PF03193.11 EXF81782.1 - 0.17 11.0 0.0 0.35 10.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 DAO PF01266.19 EXF81783.1 - 1.5e-44 152.3 0.1 1.8e-44 152.1 0.1 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF81783.1 - 3e-07 30.3 0.0 7.5e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF81783.1 - 3.4e-06 27.1 0.1 0.00052 19.9 0.1 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF81783.1 - 5e-06 25.6 0.1 0.0032 16.3 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 EXF81783.1 - 0.0011 19.0 0.0 0.013 15.5 0.0 2.2 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EXF81783.1 - 0.0012 17.9 0.0 0.0022 17.0 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.1 EXF81783.1 - 0.0033 17.2 0.0 0.016 14.9 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding GIDA PF01134.17 EXF81783.1 - 0.0044 15.9 0.0 2.3 6.9 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox PF00070.22 EXF81783.1 - 0.006 16.9 0.0 0.13 12.7 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF81783.1 - 0.0064 15.0 0.0 0.99 7.8 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein TrkA_N PF02254.13 EXF81783.1 - 0.018 15.0 0.0 0.049 13.6 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain ThiF PF00899.16 EXF81783.1 - 0.022 14.5 0.0 0.055 13.2 0.0 1.7 2 0 0 2 2 2 0 ThiF family Thi4 PF01946.12 EXF81783.1 - 0.099 11.7 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.15 EXF81783.1 - 0.14 12.3 0.0 0.25 11.4 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Sugar_tr PF00083.19 EXF81784.1 - 1.4e-63 215.0 27.9 1.9e-63 214.6 19.3 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF81784.1 - 2.6e-19 69.1 44.7 3e-14 52.5 18.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily 2-Hacid_dh_C PF02826.14 EXF81785.1 - 5.9e-53 178.6 0.0 7.8e-53 178.2 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EXF81785.1 - 2.3e-18 65.9 0.0 2.8e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EXF81785.1 - 0.00086 19.1 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Asp_Glu_race PF01177.17 EXF81786.1 - 5.3e-05 23.2 0.0 0.00015 21.7 0.0 1.6 1 1 0 1 1 1 1 Asp/Glu/Hydantoin racemase NUC173 PF08161.7 EXF81786.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 NUC173 domain Aldolase_II PF00596.16 EXF81787.1 - 1.2e-47 161.9 0.0 1.5e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain DUF1338 PF07063.8 EXF81788.1 - 1.1e-71 241.3 0.0 1.4e-71 241.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1338) Fungal_trans PF04082.13 EXF81789.1 - 2e-30 105.5 0.0 3.8e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF81789.1 - 3.9e-08 33.0 8.0 8.4e-08 32.0 5.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_71 PF03659.9 EXF81790.1 - 8.9e-145 481.9 0.3 1.5e-144 481.2 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 71 DOCK-C2 PF14429.1 EXF81791.1 - 5.4e-24 84.8 0.0 9.6e-24 84.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ded_cyto PF06920.8 EXF81791.1 - 4.3e-10 39.1 1.8 2.2e-09 36.8 1.2 2.1 1 1 0 1 1 1 1 Dedicator of cytokinesis SH3_1 PF00018.23 EXF81791.1 - 4.7e-05 22.6 0.0 0.00011 21.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EXF81791.1 - 0.0032 17.0 0.0 0.024 14.2 0.0 2.4 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EXF81791.1 - 0.061 12.8 0.0 0.29 10.6 0.0 2.2 2 0 0 2 2 2 0 Variant SH3 domain PAP2_3 PF14378.1 EXF81792.1 - 6.4e-23 81.2 11.2 1.2e-18 67.3 3.1 3.0 2 1 0 2 2 2 2 PAP2 superfamily PAP2 PF01569.16 EXF81792.1 - 0.0079 15.8 4.6 0.0079 15.8 3.2 2.4 1 1 2 3 3 3 1 PAP2 superfamily Glyco_hydro_88 PF07470.8 EXF81793.1 - 2.8e-59 200.8 2.4 3.6e-59 200.4 1.7 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 MFS_1 PF07690.11 EXF81794.1 - 3.1e-42 144.5 34.3 3.1e-42 144.5 23.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF81794.1 - 3.7e-13 48.8 7.3 6.9e-13 47.9 5.0 1.5 1 0 0 1 1 1 1 Sugar (and other) transporter TRI12 PF06609.8 EXF81794.1 - 9.3e-06 24.1 3.5 1.3e-05 23.5 2.4 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Fungal_trans PF04082.13 EXF81795.1 - 5.8e-12 45.0 0.0 9.7e-12 44.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Aminotran_5 PF00266.14 EXF81796.1 - 4.4e-35 121.1 0.0 3.1e-24 85.4 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-V p450 PF00067.17 EXF81797.1 - 1.1e-51 175.8 0.0 1.8e-51 175.1 0.0 1.3 2 0 0 2 2 2 1 Cytochrome P450 SAMP PF05924.6 EXF81797.1 - 0.33 10.1 1.0 0.81 8.9 0.7 1.6 1 0 0 1 1 1 0 SAMP Motif Epimerase PF01370.16 EXF81798.1 - 2.6e-22 79.4 0.0 3.2e-22 79.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EXF81798.1 - 2.3e-10 39.8 0.0 2e-09 36.7 0.0 2.2 2 0 0 2 2 2 1 Male sterility protein Polysacc_synt_2 PF02719.10 EXF81798.1 - 9.6e-09 34.5 0.9 7.4e-06 25.0 0.1 3.0 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EXF81798.1 - 9.9e-09 34.4 0.0 1.2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EXF81798.1 - 0.00046 18.9 0.0 0.0016 17.1 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EXF81798.1 - 0.018 14.9 1.2 4.6 7.1 0.0 2.3 2 0 0 2 2 2 0 short chain dehydrogenase KR PF08659.5 EXF81798.1 - 0.3 10.7 1.4 18 4.8 0.0 2.3 2 0 0 2 2 2 0 KR domain FSH1 PF03959.8 EXF81799.1 - 3.5e-29 101.7 0.0 4.4e-29 101.4 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EXF81799.1 - 0.00042 19.9 0.1 0.00069 19.2 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF81799.1 - 0.00045 20.0 0.2 0.0008 19.1 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EXF81799.1 - 0.0085 15.5 0.2 0.083 12.3 0.0 2.2 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EXF81799.1 - 0.048 13.5 2.2 0.12 12.2 1.5 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family ELK PF03789.8 EXF81799.1 - 0.11 12.2 0.4 0.3 10.9 0.3 1.7 1 0 0 1 1 1 0 ELK domain Polysacc_synt_3 PF13440.1 EXF81801.1 - 0.059 12.8 6.3 0.094 12.1 4.3 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Melibiase PF02065.13 EXF81802.1 - 5.4e-15 54.9 0.0 4.3e-08 32.2 0.0 2.2 2 0 0 2 2 2 2 Melibiase DUF905 PF06006.7 EXF81802.1 - 0.081 12.3 0.0 0.26 10.6 0.0 1.9 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) Aminotran_4 PF01063.14 EXF81804.1 - 1.5e-18 67.1 0.0 1.8e-18 66.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV LIME1 PF15332.1 EXF81804.1 - 0.11 11.6 0.1 0.18 10.9 0.1 1.3 1 0 0 1 1 1 0 Lck-interacting transmembrane adapter 1 DUF3328 PF11807.3 EXF81806.1 - 7.8e-53 179.3 3.8 9.7e-53 179.0 2.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Peptidase_S8 PF00082.17 EXF81807.1 - 1.4e-43 149.0 0.0 3.7e-43 147.7 0.0 1.8 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EXF81807.1 - 2.9e-12 46.9 0.0 6.5e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 EXF81807.1 - 5e-10 38.9 0.0 2.7e-09 36.6 0.0 2.3 1 1 0 1 1 1 1 PA domain FlgD_ig PF13860.1 EXF81807.1 - 1.4e-05 24.7 0.0 4e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 FlgD Ig-like domain adh_short PF00106.20 EXF81808.1 - 1.2e-22 80.6 0.0 1.5e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF81808.1 - 4.6e-08 32.9 0.0 6.5e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF81808.1 - 1.3e-06 28.3 0.0 1.8e-06 27.9 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EXF81808.1 - 4.8e-06 26.7 0.0 9.3e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EXF81808.1 - 1.6e-05 25.2 0.2 3.4e-05 24.2 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 EXF81808.1 - 0.001 18.0 0.6 0.0016 17.3 0.4 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EXF81808.1 - 0.0019 17.7 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF81808.1 - 0.0028 17.7 0.0 0.0044 17.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_2 PF03446.10 EXF81808.1 - 0.0049 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EXF81808.1 - 0.0062 16.2 0.3 0.015 14.9 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EXF81808.1 - 0.032 13.2 0.1 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase ADH_zinc_N PF00107.21 EXF81808.1 - 0.057 12.9 0.2 0.15 11.6 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase p450 PF00067.17 EXF81809.1 - 1.3e-58 198.6 0.0 2.7e-45 154.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 HAD PF12710.2 EXF81810.1 - 2.4e-07 31.0 0.0 3.3e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Glyco_hydro_88 PF07470.8 EXF81811.1 - 8.7e-09 34.8 1.4 8.7e-09 34.8 1.0 1.7 2 0 0 2 2 2 1 Glycosyl Hydrolase Family 88 Fungal_trans PF04082.13 EXF81812.1 - 1.4e-15 56.8 0.2 3e-15 55.8 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF81812.1 - 8.2e-08 32.0 12.8 8.2e-08 32.0 8.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dickkopf_N PF04706.7 EXF81812.1 - 7.2 6.8 11.6 0.82 9.8 4.6 2.0 2 0 0 2 2 2 0 Dickkopf N-terminal cysteine-rich region DUF2264 PF10022.4 EXF81813.1 - 3.2e-131 437.2 0.0 3.9e-131 436.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Redoxin PF08534.5 EXF81815.1 - 1.1e-18 67.1 0.0 1.3e-18 66.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EXF81815.1 - 2.4e-10 40.1 0.0 3.7e-08 33.1 0.0 2.1 2 0 0 2 2 2 2 AhpC/TSA family p450 PF00067.17 EXF81816.1 - 2.3e-61 207.7 0.0 3e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAA_22 PF13401.1 EXF81817.1 - 3.6e-05 23.8 0.1 0.00045 20.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EXF81817.1 - 0.0012 18.8 0.2 0.012 15.6 0.1 2.6 2 1 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EXF81817.1 - 0.0015 18.2 0.0 0.0041 16.7 0.0 1.8 1 0 0 1 1 1 1 NACHT domain Acetyltransf_1 PF00583.19 EXF81818.1 - 4.9e-10 39.3 0.2 1.8e-09 37.4 0.2 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF81818.1 - 2.6e-09 37.1 0.0 1.2e-07 31.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EXF81818.1 - 1.1e-05 25.5 0.3 0.0002 21.4 0.0 2.4 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EXF81818.1 - 0.00016 21.3 0.0 0.00027 20.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EXF81818.1 - 0.0036 17.1 0.1 0.009 15.8 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain MFS_1 PF07690.11 EXF81819.1 - 4.7e-27 94.6 32.5 4.7e-27 94.6 22.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2207 PF09972.4 EXF81819.1 - 2.1 6.8 4.3 10 4.5 1.8 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF4064 PF13273.1 EXF81819.1 - 8.3 6.5 12.3 28 4.9 4.3 3.7 2 2 0 2 2 2 0 Protein of unknown function (DUF4064) adh_short PF00106.20 EXF81820.1 - 6.2e-28 97.7 6.1 7.6e-28 97.5 4.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF81820.1 - 3.5e-17 62.9 0.8 4.8e-17 62.5 0.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF81820.1 - 3.3e-13 49.6 3.3 4.7e-13 49.2 2.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF81820.1 - 0.00041 19.8 3.0 0.00086 18.8 2.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EXF81820.1 - 0.033 14.5 1.1 0.11 12.8 0.8 2.0 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_10 PF13460.1 EXF81820.1 - 0.18 11.7 4.5 1.1 9.1 3.1 2.0 1 1 0 1 1 1 0 NADH(P)-binding Sugar_tr PF00083.19 EXF81821.1 - 2.2e-83 280.3 24.8 2.6e-83 280.0 17.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF81821.1 - 3.5e-20 72.0 48.6 1.9e-13 49.8 16.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF81821.1 - 9.9e-05 20.7 3.1 0.00018 19.8 2.1 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF1228 PF06779.9 EXF81821.1 - 1.1 9.3 9.5 1 9.4 0.1 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF1228) adh_short PF00106.20 EXF81822.1 - 1.6e-26 93.1 0.3 2.4e-26 92.6 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF81822.1 - 7.8e-21 74.9 0.0 9.4e-21 74.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF81822.1 - 6.5e-08 32.4 0.2 1.1e-07 31.7 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EXF81822.1 - 0.01 14.7 0.1 0.022 13.6 0.0 1.6 1 1 0 1 1 1 0 Male sterility protein Fungal_trans_2 PF11951.3 EXF81823.1 - 1.9e-15 56.3 2.7 8.6e-11 41.0 0.5 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF81823.1 - 8.5e-08 31.9 11.5 2.3e-07 30.5 8.0 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF81823.1 - 0.81 8.5 5.5 0.12 11.2 1.0 1.7 2 0 0 2 2 2 0 Fungal specific transcription factor domain MamL-1 PF09596.5 EXF81823.1 - 1.6 8.5 6.6 11 5.8 2.2 2.8 2 0 0 2 2 2 0 MamL-1 domain F_bP_aldolase PF01116.15 EXF81824.1 - 4.9e-75 252.3 0.1 5.4e-75 252.1 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II SGL PF08450.7 EXF81825.1 - 1.1e-29 103.5 0.0 2.1e-29 102.6 0.0 1.4 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EXF81825.1 - 0.00059 19.7 0.0 0.0016 18.3 0.0 1.7 1 0 0 1 1 1 1 Arylesterase Str_synth PF03088.11 EXF81825.1 - 0.0024 17.8 0.0 0.0067 16.4 0.0 1.8 1 1 0 1 1 1 1 Strictosidine synthase NHL PF01436.16 EXF81825.1 - 0.0024 17.7 4.0 0.83 9.7 0.0 3.9 3 0 0 3 3 3 1 NHL repeat Reg_prop PF07494.6 EXF81825.1 - 0.059 13.4 1.6 2 8.7 0.1 3.5 3 0 0 3 3 3 0 Two component regulator propeller OPT PF03169.10 EXF81826.1 - 1.2e-150 502.9 52.2 1.4e-150 502.7 36.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein FMN_dh PF01070.13 EXF81827.1 - 9.3e-86 287.8 0.2 9.6e-50 169.4 0.0 2.0 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.20 EXF81827.1 - 0.0037 16.2 0.1 0.0066 15.3 0.1 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EXF81827.1 - 0.012 14.5 0.1 0.027 13.3 0.0 1.4 1 1 0 1 1 1 0 Conserved region in glutamate synthase ThiG PF05690.9 EXF81827.1 - 0.017 14.1 0.0 2.3 7.2 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG IGPS PF00218.16 EXF81827.1 - 0.036 13.1 0.0 0.14 11.1 0.0 1.8 1 1 1 2 2 2 0 Indole-3-glycerol phosphate synthase DHO_dh PF01180.16 EXF81827.1 - 0.039 12.9 0.6 2.1 7.2 0.0 2.4 3 0 0 3 3 3 0 Dihydroorotate dehydrogenase SLAM PF06214.6 EXF81827.1 - 0.056 13.3 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Signaling lymphocytic activation molecule (SLAM) protein Pribosyltran PF00156.22 EXF81827.1 - 0.091 12.4 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Phosphoribosyl transferase domain adh_short PF00106.20 EXF81828.1 - 6.5e-24 84.7 1.4 8.6e-24 84.3 0.9 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF81828.1 - 2e-22 80.1 0.0 2.7e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF81828.1 - 2.4e-07 30.5 0.1 3.7e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 KR domain Aldo_ket_red PF00248.16 EXF81829.1 - 1.7e-49 168.1 0.0 2.1e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF1493 PF07377.7 EXF81829.1 - 0.12 12.4 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) FAD_binding_3 PF01494.14 EXF81830.1 - 9.7e-22 77.4 0.0 1.9e-21 76.5 0.0 1.3 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EXF81830.1 - 2.4e-05 24.2 0.1 6.2e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF81830.1 - 9.6e-05 21.4 0.1 0.0002 20.3 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF81830.1 - 0.00013 21.9 0.1 0.00024 21.0 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF81830.1 - 0.00026 21.3 0.0 0.0021 18.4 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF81830.1 - 0.00026 19.9 0.0 0.0011 17.8 0.0 1.8 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 EXF81830.1 - 0.00094 17.7 0.1 0.0014 17.2 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein SE PF08491.5 EXF81830.1 - 0.0031 16.3 0.0 0.0064 15.3 0.0 1.4 1 0 0 1 1 1 1 Squalene epoxidase 3HCDH_N PF02737.13 EXF81830.1 - 0.0036 16.9 0.0 0.0059 16.2 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EXF81830.1 - 0.0075 15.3 0.2 0.028 13.5 0.2 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EXF81830.1 - 0.087 11.9 0.1 0.14 11.2 0.1 1.2 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.16 EXF81830.1 - 0.11 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.19 EXF81830.1 - 0.18 10.6 1.7 0.19 10.5 0.0 1.9 3 0 0 3 3 3 0 FAD binding domain Peptidase_M24 PF00557.19 EXF81831.1 - 3.7e-45 154.0 0.1 4.5e-45 153.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EXF81831.1 - 0.00017 21.3 2.7 0.00017 21.3 1.9 2.0 2 0 0 2 2 2 1 MYND finger Cornichon PF03311.9 EXF81832.1 - 1.3e-54 183.7 11.3 1.5e-54 183.5 7.8 1.0 1 0 0 1 1 1 1 Cornichon protein WD40 PF00400.27 EXF81833.1 - 5.3e-43 143.4 8.4 1.1e-09 37.7 0.1 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EXF81833.1 - 0.00093 17.4 0.9 1 7.3 0.0 3.0 1 1 1 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.6 EXF81833.1 - 0.0048 16.6 0.3 0.81 9.3 0.0 2.9 2 1 2 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EXF81833.1 - 0.027 13.2 0.3 0.19 10.4 0.2 2.4 1 1 0 1 1 1 0 Nup133 N terminal like Lin-8 PF03353.10 EXF81834.1 - 0.023 13.9 2.6 0.028 13.6 1.8 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Spt5_N PF11942.3 EXF81834.1 - 0.051 14.2 0.5 0.091 13.3 0.4 1.5 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal Pol_alpha_B_N PF08418.5 EXF81834.1 - 0.13 11.7 4.3 0.16 11.4 3.0 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF605 PF04652.11 EXF81834.1 - 1.8 7.8 10.7 2.1 7.6 7.4 1.1 1 0 0 1 1 1 0 Vta1 like SCIMP PF15050.1 EXF81834.1 - 3.2 7.6 8.5 1.2 9.0 1.2 2.3 1 1 0 2 2 2 0 SCIMP protein SR-25 PF10500.4 EXF81834.1 - 5.4 6.4 16.9 8.9 5.7 11.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF566 PF04484.7 EXF81834.1 - 9.3 5.6 10.0 10 5.5 7.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF3153 PF11353.3 EXF81835.1 - 0.23 10.8 2.3 0.54 9.6 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3153) Arginase PF00491.16 EXF81836.1 - 2.3e-45 155.0 0.1 2.9e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 Arginase family Fungal_trans PF04082.13 EXF81839.1 - 3.7e-19 68.6 0.2 6.1e-19 67.8 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF81839.1 - 2.2e-05 24.2 8.3 4.2e-05 23.3 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Myb_DNA-bind_6 PF13921.1 EXF81842.1 - 0.00038 20.5 0.1 0.0031 17.5 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EXF81842.1 - 0.0091 16.0 0.1 0.27 11.3 0.3 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain Exonuc_VIII PF06630.6 EXF81842.1 - 0.062 12.6 0.1 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Enterobacterial exodeoxyribonuclease VIII 14-3-3 PF00244.15 EXF81843.1 - 9.4e-10 37.9 0.0 5.9e-09 35.3 0.0 1.9 2 0 0 2 2 2 1 14-3-3 protein Myb_DNA-bind_6 PF13921.1 EXF81844.1 - 1e-05 25.4 0.1 2.7e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EXF81844.1 - 0.0046 16.9 0.1 0.0094 15.9 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4202 PF13875.1 EXF81845.1 - 1.1e-73 246.8 0.1 1.2e-73 246.6 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4202) DUF3744 PF12558.3 EXF81845.1 - 0.14 12.6 0.0 0.33 11.4 0.0 1.6 1 0 0 1 1 1 0 ATP-binding cassette cobalt transporter FMN_dh PF01070.13 EXF81846.1 - 5.7e-111 370.8 0.0 7.4e-111 370.4 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EXF81846.1 - 2.3e-18 65.7 0.0 4.1e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NMO PF03060.10 EXF81846.1 - 0.00044 19.4 0.4 0.0011 18.2 0.1 1.6 1 1 1 2 2 2 1 Nitronate monooxygenase Glu_synthase PF01645.12 EXF81846.1 - 0.0008 18.4 0.0 0.0014 17.6 0.0 1.4 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EXF81846.1 - 0.00096 18.1 0.8 0.006 15.5 0.3 2.2 2 1 1 3 3 3 1 IMP dehydrogenase / GMP reductase domain Peptidase_M19 PF01244.16 EXF81846.1 - 0.12 11.2 0.0 0.49 9.2 0.0 1.9 2 1 0 2 2 2 0 Membrane dipeptidase (Peptidase family M19) Dus PF01207.12 EXF81846.1 - 0.14 10.9 0.1 4.6 5.9 0.0 2.7 2 1 1 3 3 3 0 Dihydrouridine synthase (Dus) Syndecan PF01034.15 EXF81847.1 - 0.00011 21.8 0.1 0.00022 20.8 0.1 1.4 1 0 0 1 1 1 1 Syndecan domain EphA2_TM PF14575.1 EXF81847.1 - 0.013 15.9 0.3 0.064 13.6 0.0 2.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Alpha_GJ PF03229.8 EXF81847.1 - 0.014 15.7 4.3 0.014 15.7 3.0 2.2 2 0 0 2 2 2 0 Alphavirus glycoprotein J DUF1191 PF06697.7 EXF81847.1 - 0.05 12.4 0.0 0.077 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Mid2 PF04478.7 EXF81847.1 - 0.051 12.9 0.4 0.11 11.9 0.3 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor TMEM154 PF15102.1 EXF81847.1 - 0.054 13.1 1.3 0.064 12.9 0.0 1.8 2 0 0 2 2 2 0 TMEM154 protein family SKG6 PF08693.5 EXF81847.1 - 0.081 12.2 3.4 0.21 10.9 2.3 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Spb1_C PF07780.7 EXF81849.1 - 4.4e-69 232.2 47.6 4.4e-69 232.2 33.0 4.4 2 1 1 3 3 3 1 Spb1 C-terminal domain FtsJ PF01728.14 EXF81849.1 - 2.4e-56 190.5 0.0 4.4e-56 189.7 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.3 EXF81849.1 - 4e-53 179.1 13.8 4e-53 179.1 9.6 5.0 4 2 1 5 5 5 1 Domain of unknown function (DUF3381) Methyltransf_23 PF13489.1 EXF81849.1 - 0.065 12.9 0.0 0.21 11.3 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain WD40 PF00400.27 EXF81850.1 - 3.5e-20 71.0 0.4 6.4e-05 22.6 0.0 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat Heme_oxygenase PF01126.15 EXF81851.1 - 2e-07 30.7 0.0 1.2e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 Heme oxygenase DUF914 PF06027.7 EXF81852.1 - 2.4e-07 29.9 7.9 2.4e-07 29.9 5.5 1.9 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EXF81852.1 - 1.1e-06 28.7 33.5 5.9e-05 23.1 3.2 3.1 3 0 0 3 3 3 2 EamA-like transporter family TPT PF03151.11 EXF81852.1 - 0.00014 21.4 28.7 0.00087 18.9 1.9 3.0 3 0 0 3 3 3 2 Triose-phosphate Transporter family UAA PF08449.6 EXF81852.1 - 0.00069 18.6 11.4 0.00069 18.6 7.9 1.9 2 0 0 2 2 2 1 UAA transporter family EmrE PF13536.1 EXF81852.1 - 0.0012 19.0 5.1 0.0012 19.0 3.5 3.6 3 2 0 3 3 3 1 Multidrug resistance efflux transporter Brr6_like_C_C PF10104.4 EXF81852.1 - 0.51 9.8 0.1 0.51 9.8 0.0 2.7 3 0 0 3 3 3 0 Di-sulfide bridge nucleocytoplasmic transport domain UPF0546 PF10639.4 EXF81852.1 - 5.9 6.7 10.8 0.63 9.8 0.9 3.2 3 0 0 3 3 3 0 Uncharacterised protein family UPF0546 FA_desaturase PF00487.19 EXF81852.1 - 6.6 6.0 10.1 0.27 10.6 0.8 2.8 3 0 0 3 3 3 0 Fatty acid desaturase Ras PF00071.17 EXF81853.1 - 4.3e-57 192.0 0.0 5.1e-57 191.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EXF81853.1 - 1.4e-18 67.5 0.0 2.1e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EXF81853.1 - 2.8e-13 49.4 0.0 3.4e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EXF81853.1 - 1.6e-07 31.2 0.0 2.2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EXF81853.1 - 8.5e-07 28.3 0.0 1e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EXF81853.1 - 2.2e-06 27.2 0.0 4.4e-05 22.9 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EXF81853.1 - 0.00067 19.7 0.0 0.0015 18.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EXF81853.1 - 0.00099 18.3 0.1 0.0019 17.4 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_5 PF07728.9 EXF81853.1 - 0.0018 17.9 0.0 0.0064 16.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) SRPRB PF09439.5 EXF81853.1 - 0.002 17.3 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.1 EXF81853.1 - 0.0039 17.1 0.0 0.011 15.7 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.1 EXF81853.1 - 0.0043 16.6 0.1 0.0077 15.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EXF81853.1 - 0.0054 16.4 0.1 0.01 15.5 0.0 1.5 2 0 0 2 2 2 1 Archaeal ATPase PduV-EutP PF10662.4 EXF81853.1 - 0.0064 15.9 0.0 0.1 12.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_10 PF12846.2 EXF81853.1 - 0.0075 15.7 0.2 0.012 15.0 0.1 1.4 1 1 0 1 1 1 1 AAA-like domain ATP_bind_1 PF03029.12 EXF81853.1 - 0.0079 15.7 0.3 0.28 10.6 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Septin PF00735.13 EXF81853.1 - 0.014 14.4 0.1 0.032 13.2 0.0 1.7 2 0 0 2 2 2 0 Septin NTPase_1 PF03266.10 EXF81853.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 NTPase MobB PF03205.9 EXF81853.1 - 0.023 14.4 0.1 0.058 13.1 0.0 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EXF81853.1 - 0.033 13.6 0.0 0.076 12.4 0.0 1.6 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NB-ARC PF00931.17 EXF81853.1 - 0.07 11.9 0.2 0.35 9.6 0.1 1.9 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.7 EXF81853.1 - 0.086 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain FeoB_N PF02421.13 EXF81853.1 - 0.091 12.0 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Ferrous iron transport protein B RNA_helicase PF00910.17 EXF81853.1 - 0.12 12.5 0.0 0.43 10.7 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_3 PF07726.6 EXF81854.1 - 0.0039 16.7 0.0 0.0078 15.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) GDA1_CD39 PF01150.12 EXF81855.1 - 9.1e-100 334.1 0.0 1.1e-99 333.8 0.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.11 EXF81855.1 - 0.016 14.3 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family PUL PF08324.6 EXF81856.1 - 4e-40 137.3 0.0 5.5e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.9 EXF81856.1 - 4.2e-33 114.2 0.0 6.6e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 PPPDE putative peptidase domain Thioredoxin PF00085.15 EXF81856.1 - 1.3e-11 44.0 0.0 2.6e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.1 EXF81856.1 - 0.012 15.0 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Redoxin PF08534.5 EXF81856.1 - 0.022 14.3 0.0 0.041 13.4 0.0 1.4 1 0 0 1 1 1 0 Redoxin Glutaredoxin PF00462.19 EXF81856.1 - 0.04 13.8 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_9 PF14595.1 EXF81856.1 - 0.13 11.7 0.0 0.26 10.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.1 EXF81856.1 - 0.19 11.9 0.1 0.63 10.2 0.1 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain Kinesin PF00225.18 EXF81857.1 - 5.5e-113 377.0 0.1 9.1e-113 376.3 0.1 1.3 1 0 0 1 1 1 1 Kinesin motor domain IF4E PF01652.13 EXF81858.1 - 2e-38 131.5 0.6 2.6e-38 131.1 0.4 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Lactamase_B PF00753.22 EXF81859.1 - 3.2e-27 95.4 0.8 1.1e-26 93.6 0.6 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EXF81859.1 - 2.8e-06 26.9 0.0 4.6e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain LVIVD PF08309.6 EXF81859.1 - 0.0043 16.0 0.3 0.0085 15.0 0.2 1.4 1 0 0 1 1 1 1 LVIVD repeat Peripla_BP_4 PF13407.1 EXF81859.1 - 0.021 14.1 0.2 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 Periplasmic binding protein domain EF-hand_9 PF14658.1 EXF81859.1 - 0.092 12.6 0.0 2.9 7.8 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain Las1 PF04031.8 EXF81860.1 - 9.6e-59 197.4 0.0 1.7e-58 196.6 0.0 1.4 1 0 0 1 1 1 1 Las1-like TFIIA PF03153.8 EXF81860.1 - 0.064 13.1 4.0 0.12 12.2 2.6 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Saccharop_dh PF03435.13 EXF81861.1 - 6.8e-135 449.9 0.0 7.9e-135 449.7 0.0 1.0 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EXF81861.1 - 3.1e-06 27.3 0.4 5.9e-06 26.4 0.3 1.4 1 0 0 1 1 1 1 NADH(P)-binding Shikimate_DH PF01488.15 EXF81861.1 - 4.9e-05 23.4 0.1 9.6e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase IlvN PF07991.7 EXF81861.1 - 0.0065 15.8 0.3 0.046 13.0 0.0 2.5 2 1 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EXF81861.1 - 0.033 14.6 0.1 0.09 13.2 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 EXF81861.1 - 0.04 14.4 0.5 0.14 12.6 0.1 2.1 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.13 EXF81861.1 - 0.1 12.6 0.6 0.67 9.9 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain EB PF01683.13 EXF81863.1 - 0.038 14.0 1.5 0.038 14.0 1.0 1.8 2 0 0 2 2 2 0 EB module PfkB PF00294.19 EXF81864.1 - 0.037 13.1 0.0 0.065 12.3 0.0 1.4 1 1 0 1 1 1 0 pfkB family carbohydrate kinase WSC PF01822.14 EXF81865.1 - 1.7e-72 239.3 87.1 8e-20 70.5 8.1 5.8 5 0 0 5 5 5 4 WSC domain peroxidase PF00141.18 EXF81865.1 - 4.2e-22 78.7 0.1 8.7e-22 77.7 0.1 1.5 1 0 0 1 1 1 1 Peroxidase MARVEL PF01284.18 EXF81866.1 - 0.00038 20.2 17.6 0.011 15.5 12.5 2.1 1 1 0 1 1 1 1 Membrane-associating domain DUF3422 PF11902.3 EXF81866.1 - 0.58 8.9 1.4 2.9 6.6 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3422) DUF3402 PF11882.3 EXF81867.1 - 8.1e-157 522.4 0.0 1.1e-156 522.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EXF81867.1 - 6.8e-74 248.3 0.1 1e-73 247.7 0.0 1.3 1 0 0 1 1 1 1 N1221-like protein NAD_kinase PF01513.16 EXF81868.1 - 2.4e-70 236.5 0.0 3.5e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase DUF2431 PF10354.4 EXF81869.1 - 0.12 12.3 0.3 2.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2431) Med21 PF11221.3 EXF81869.1 - 0.19 11.7 6.3 0.055 13.4 1.7 1.9 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Abhydrolase_4 PF08386.5 EXF81871.1 - 1.2e-17 63.6 0.0 3.5e-17 62.1 0.0 1.8 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EXF81871.1 - 2.4e-11 43.6 0.0 2.6e-07 30.4 0.0 3.1 3 0 0 3 3 3 3 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EXF81871.1 - 4.8e-08 33.1 3.7 1.2e-06 28.5 2.6 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF81871.1 - 0.0002 21.1 0.0 0.15 11.7 0.0 2.4 2 0 0 2 2 2 2 Alpha/beta hydrolase family DUF2823 PF11034.3 EXF81872.1 - 1.9e-30 104.8 10.2 2.1e-30 104.6 7.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2823) DUF3756 PF12581.3 EXF81872.1 - 0.063 12.9 0.3 0.098 12.3 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3756) EBP PF05241.7 EXF81873.1 - 3.3e-72 241.5 8.2 4e-72 241.3 5.7 1.0 1 0 0 1 1 1 1 Emopamil binding protein PsbN PF02468.10 EXF81873.1 - 0.027 14.0 1.2 0.027 14.0 0.8 2.5 3 0 0 3 3 3 0 Photosystem II reaction centre N protein (psbN) DUF788 PF05620.6 EXF81873.1 - 4.9 6.9 9.1 0.49 10.2 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF788) UBN2_3 PF14244.1 EXF81874.1 - 0.051 13.1 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type SID-1_RNA_chan PF13965.1 EXF81875.1 - 0.35 8.9 6.2 0.55 8.3 4.3 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 PAP2 PF01569.16 EXF81876.1 - 3.8e-16 58.9 2.2 3.8e-16 58.9 1.5 1.9 1 1 1 2 2 2 1 PAP2 superfamily DUF1345 PF07077.6 EXF81876.1 - 0.1 12.1 2.7 0.26 10.7 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) DUF212 PF02681.9 EXF81876.1 - 0.13 11.9 0.0 3.4 7.3 0.0 2.3 2 0 0 2 2 2 0 Divergent PAP2 family RWD PF05773.17 EXF81877.1 - 7.5e-22 77.3 0.0 1.3e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 EXF81877.1 - 3.7e-19 68.3 34.8 2.6e-14 52.8 2.7 4.0 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 EXF81877.1 - 0.00041 20.1 7.8 0.00041 20.1 5.4 3.5 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.1 EXF81877.1 - 0.0024 17.8 8.5 0.0024 17.8 5.9 4.0 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EXF81877.1 - 0.0075 15.9 4.0 0.0075 15.9 2.8 3.1 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EXF81877.1 - 0.0077 15.8 8.4 0.0077 15.8 5.8 4.3 3 1 1 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EXF81877.1 - 0.014 15.1 8.1 0.014 15.1 5.6 4.1 2 1 1 3 3 3 0 zinc-RING finger domain FYVE PF01363.16 EXF81877.1 - 2.5 8.0 25.4 3.6 7.5 0.5 3.5 3 0 0 3 3 3 0 FYVE zinc finger MFS_1 PF07690.11 EXF81878.1 - 3.4e-21 75.3 37.5 3.4e-21 75.3 26.0 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EXF81878.1 - 0.0084 15.8 0.3 0.024 14.4 0.2 1.8 1 0 0 1 1 1 1 MFS_1 like family DUF3487 PF11990.3 EXF81878.1 - 0.45 9.9 4.5 0.49 9.7 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) Dicty_REP PF05086.7 EXF81878.1 - 1.7 6.2 2.2 2.3 5.8 1.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.12 EXF81878.1 - 6.1 6.6 18.5 12 5.6 12.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Glyco_hydro_72 PF03198.9 EXF81879.1 - 2.8e-119 397.7 5.9 3.8e-119 397.3 4.1 1.1 1 0 0 1 1 1 1 Glucanosyltransferase X8 PF07983.8 EXF81879.1 - 5.2e-23 81.3 4.2 1.6e-22 79.7 2.9 1.9 1 0 0 1 1 1 1 X8 domain BIR PF00653.16 EXF81880.1 - 5.8e-11 42.6 0.1 8.5e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 Inhibitor of Apoptosis domain Mac PF12464.3 EXF81882.1 - 6.7e-20 70.8 0.0 9.7e-20 70.3 0.0 1.2 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 EXF81882.1 - 1.7e-14 52.5 11.6 1.5e-11 43.2 2.7 3.7 2 1 1 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EXF81882.1 - 1.6e-11 43.5 4.4 1.6e-11 43.5 3.0 3.4 4 1 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase Subtilosin_A PF11420.3 EXF81882.1 - 0.012 15.6 0.4 0.043 13.8 0.1 2.0 2 0 0 2 2 2 0 Bacteriocin subtilosin A DUF2306 PF10067.4 EXF81883.1 - 2.5e-18 66.0 6.0 2.5e-18 66.0 4.1 1.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) DUF998 PF06197.8 EXF81883.1 - 0.0027 17.0 7.2 0.0027 17.0 5.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF998) Cerato-platanin PF07249.7 EXF81884.1 - 2.7e-05 24.1 0.6 5e-05 23.2 0.1 1.7 2 0 0 2 2 2 1 Cerato-platanin Amidase PF01425.16 EXF81885.1 - 6.7e-55 186.7 0.1 6.4e-54 183.4 0.1 2.0 1 1 0 1 1 1 1 Amidase Pyr_redox_3 PF13738.1 EXF81886.1 - 1.5e-23 83.9 0.1 2.1e-22 80.1 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EXF81886.1 - 2.8e-17 62.1 0.1 5.4e-16 57.8 0.0 2.1 1 1 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EXF81886.1 - 1.7e-16 60.7 0.0 7e-14 52.1 0.0 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF81886.1 - 3.8e-16 58.9 0.3 1.8e-13 50.1 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 EXF81886.1 - 3e-10 39.7 0.6 3.8e-06 26.2 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 EXF81886.1 - 1.6e-06 28.4 0.1 0.79 10.1 0.0 3.6 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF81886.1 - 2.6e-06 26.5 0.7 0.0002 20.3 0.0 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EXF81886.1 - 2.6e-05 24.0 1.3 0.14 11.9 0.1 3.1 2 1 1 3 3 3 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EXF81886.1 - 0.00033 19.6 0.1 0.048 12.5 0.0 3.1 2 1 1 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EXF81886.1 - 0.00081 18.3 0.3 0.14 10.9 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 EXF81886.1 - 0.0017 16.9 0.4 0.4 9.0 0.0 2.7 3 0 0 3 3 3 2 HI0933-like protein Thi4 PF01946.12 EXF81886.1 - 0.012 14.6 0.0 0.48 9.4 0.0 2.8 3 0 0 3 3 3 0 Thi4 family GIDA PF01134.17 EXF81886.1 - 0.019 13.8 1.2 7.4 5.3 0.0 3.1 3 0 0 3 3 3 0 Glucose inhibited division protein A ApbA PF02558.11 EXF81886.1 - 0.036 13.5 0.0 0.21 11.0 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_binding_8 PF13450.1 EXF81886.1 - 0.1 12.6 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain TPR_11 PF13414.1 EXF81887.1 - 2.7e-14 52.5 1.1 3.5e-08 32.9 0.1 2.5 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 EXF81887.1 - 1.3e-10 40.3 6.7 2.5e-06 26.9 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EXF81887.1 - 3.4e-08 32.7 3.1 0.0024 17.3 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EXF81887.1 - 1.2e-05 24.7 0.4 0.0032 17.1 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EXF81887.1 - 7.1e-05 23.3 1.3 0.0018 18.9 0.5 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EXF81887.1 - 0.00012 21.9 1.7 0.0026 17.6 0.2 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EXF81887.1 - 0.00075 19.7 0.4 0.005 17.1 0.1 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EXF81887.1 - 0.0015 18.9 3.2 0.094 13.3 0.1 3.1 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EXF81887.1 - 0.026 14.4 1.0 0.53 10.3 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.1 EXF81887.1 - 0.11 12.3 2.5 1.4 8.8 1.1 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.9 EXF81887.1 - 1.2 9.8 6.3 5.7 7.6 0.4 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Josephin PF02099.12 EXF81888.1 - 0.13 11.8 0.1 0.14 11.7 0.1 1.2 1 0 0 1 1 1 0 Josephin UQ_con PF00179.21 EXF81889.1 - 2.1e-25 88.7 0.0 5.5e-25 87.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme IBR PF01485.16 EXF81889.1 - 0.0066 16.3 1.9 0.019 14.8 1.3 1.7 1 0 0 1 1 1 1 IBR domain Glyco_hydro_6 PF01341.12 EXF81890.1 - 6e-108 360.7 2.3 8e-108 360.3 1.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 CBM_1 PF00734.13 EXF81890.1 - 2.1e-13 49.6 11.6 2.1e-13 49.6 8.0 2.1 2 0 0 2 2 2 1 Fungal cellulose binding domain HD_4 PF13328.1 EXF81890.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 HD domain Med3 PF11593.3 EXF81890.1 - 0.63 9.2 7.3 0.83 8.8 5.1 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Yeast-kill-tox PF09207.6 EXF81890.1 - 1.1 9.6 10.2 0.22 11.9 2.5 2.9 3 0 0 3 3 3 0 Yeast killer toxin Adap_comp_sub PF00928.16 EXF81893.1 - 2.2e-84 282.6 0.0 2.9e-84 282.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EXF81893.1 - 6.9e-05 22.5 0.2 0.00012 21.7 0.1 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1081 PF06448.6 EXF81893.1 - 0.012 15.4 0.1 0.027 14.3 0.1 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1081) Kdo PF06293.9 EXF81894.1 - 0.022 13.8 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cu-oxidase_3 PF07732.10 EXF81895.1 - 2.5e-39 133.6 4.1 6.1e-39 132.4 2.9 1.7 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EXF81895.1 - 4.9e-35 120.0 0.5 4.9e-35 120.0 0.4 3.2 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EXF81895.1 - 1e-21 77.5 2.1 2.9e-21 76.0 0.1 2.7 3 1 0 3 3 3 1 Multicopper oxidase E1-E2_ATPase PF00122.15 EXF81897.1 - 6.6e-44 149.6 8.0 1.2e-43 148.7 5.6 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EXF81897.1 - 3.4e-23 83.2 0.0 5.9e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EXF81897.1 - 1.2e-15 58.1 0.0 2.7e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EXF81897.1 - 5.7e-05 22.8 0.0 0.00031 20.3 0.0 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EXF81897.1 - 0.00033 20.7 0.4 0.00033 20.7 0.3 2.5 2 0 0 2 2 2 1 Heavy-metal-associated domain Zn_clus PF00172.13 EXF81898.1 - 0.0019 18.0 3.6 0.0045 16.8 2.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease PF00324.16 EXF81899.1 - 2.9e-126 421.6 34.0 3.6e-126 421.3 23.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF81899.1 - 2.1e-42 145.1 39.0 2.6e-42 144.8 27.0 1.1 1 0 0 1 1 1 1 Amino acid permease Nucleos_tra2_C PF07662.8 EXF81900.1 - 6.5e-72 241.3 1.9 6.5e-72 241.3 1.3 2.5 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EXF81900.1 - 2.4e-21 75.8 2.4 2.4e-21 75.8 1.7 2.7 2 0 0 2 2 2 1 Na+ dependent nucleoside transporter N-terminus ATP1G1_PLM_MAT8 PF02038.11 EXF81900.1 - 0.53 9.3 4.2 2.1 7.4 1.4 2.6 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family Amidase PF01425.16 EXF81901.1 - 4.2e-70 236.8 0.1 7.4e-69 232.7 0.0 2.0 1 1 0 1 1 1 1 Amidase NST1 PF13945.1 EXF81902.1 - 0.16 12.0 2.9 0.22 11.5 2.0 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator Pox_H7 PF04787.7 EXF81902.1 - 0.88 9.3 3.0 1.2 8.9 2.1 1.1 1 0 0 1 1 1 0 Late protein H7 HK97-gp10_like PF04883.7 EXF81902.1 - 3.4 8.6 8.0 6.7 7.7 5.6 1.5 1 0 0 1 1 1 0 Bacteriophage HK97-gp10, putative tail-component DUF3987 PF13148.1 EXF81902.1 - 3.6 6.0 9.4 6.5 5.2 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) NARP1 PF12569.3 EXF81902.1 - 4.1 6.0 8.1 5.3 5.6 5.6 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2413 PF10310.4 EXF81902.1 - 4.9 5.8 9.3 0.17 10.6 2.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2413) Polyketide_cyc2 PF10604.4 EXF81904.1 - 3.8e-10 40.0 0.2 4.4e-10 39.8 0.1 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 EXF81904.1 - 0.0011 19.0 0.0 0.0017 18.3 0.0 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF1857 PF08982.6 EXF81904.1 - 0.041 13.4 0.2 0.21 11.1 0.1 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1857) MFS_1 PF07690.11 EXF81906.1 - 2.1e-46 158.2 26.3 7.9e-44 149.8 8.6 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF81906.1 - 1.3e-14 53.7 0.3 1.3e-14 53.7 0.2 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.8 EXF81906.1 - 0.00089 17.4 6.5 0.00089 17.4 4.5 2.2 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_2 PF13347.1 EXF81906.1 - 0.0011 17.4 8.0 0.0011 17.4 5.5 3.0 3 1 0 3 3 3 1 MFS/sugar transport protein PsaX PF08078.7 EXF81906.1 - 0.13 12.1 2.0 0.68 9.9 0.3 2.9 2 0 0 2 2 2 0 PsaX family DUF3317 PF11779.3 EXF81906.1 - 7.5 6.0 9.6 0.14 11.6 1.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3317) DUF4536 PF15055.1 EXF81907.1 - 0.0015 18.5 0.2 0.0041 17.1 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4536) DUF2305 PF10230.4 EXF81908.1 - 1.5e-58 198.3 0.0 2.8e-58 197.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) MFS_1 PF07690.11 EXF81908.1 - 8.1e-25 87.2 36.7 1.7e-24 86.2 25.5 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily Abhydrolase_6 PF12697.2 EXF81908.1 - 1.1e-05 25.4 0.2 1.7e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 EXF81909.1 - 5.4e-26 91.1 49.0 8.3e-16 57.6 14.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pec_lyase_C PF00544.14 EXF81910.1 - 4e-49 166.8 3.2 5.4e-49 166.3 2.2 1.2 1 0 0 1 1 1 1 Pectate lyase Abhydrolase_1 PF00561.15 EXF81911.1 - 8.4e-12 45.1 0.1 1.4e-11 44.3 0.1 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EXF81911.1 - 2.8e-10 40.4 0.0 4.3e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF81911.1 - 0.073 12.8 0.1 2.1 8.0 0.1 2.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF3288 PF11691.3 EXF81911.1 - 0.14 11.9 0.1 0.27 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3288) RPE65 PF03055.10 EXF81912.1 - 9.4e-120 400.4 0.0 1.1e-119 400.2 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Abhydrolase_3 PF07859.8 EXF81913.1 - 1.8e-20 73.4 0.0 6.7e-19 68.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF81913.1 - 6.7e-11 42.1 0.0 1.1e-10 41.4 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF81913.1 - 2.2e-09 36.8 0.0 8.6e-06 25.1 0.0 2.9 3 0 0 3 3 3 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EXF81913.1 - 6.2e-07 29.5 0.1 8.8e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EXF81913.1 - 0.00013 20.7 0.1 0.00085 18.1 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Chlorophyllase2 PF12740.2 EXF81913.1 - 0.0019 17.1 0.0 0.0025 16.7 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme DLH PF01738.13 EXF81913.1 - 0.0058 15.9 0.0 0.89 8.7 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EXF81913.1 - 0.0063 15.9 0.0 0.78 9.1 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase AXE1 PF05448.7 EXF81913.1 - 0.095 11.1 0.1 0.49 8.8 0.0 1.9 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) ABA_GPCR PF12430.3 EXF81914.1 - 0.0065 15.6 0.0 0.0089 15.1 0.0 1.1 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor p450 PF00067.17 EXF81915.1 - 1.3e-34 119.5 0.1 1.3e-22 79.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 DUF1993 PF09351.5 EXF81917.1 - 1.4e-51 174.6 0.1 1.6e-51 174.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) TBCA PF02970.11 EXF81917.1 - 0.032 14.2 0.1 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 Tubulin binding cofactor A Pyr_redox_3 PF13738.1 EXF81918.1 - 9.3e-15 55.2 0.1 8.6e-13 48.8 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF81918.1 - 1.4e-06 28.2 0.0 0.0015 18.4 0.0 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF81918.1 - 2.6e-06 26.6 0.7 7.4e-05 21.8 0.2 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EXF81918.1 - 2e-05 22.9 0.3 0.00038 18.7 0.1 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Amino_oxidase PF01593.19 EXF81918.1 - 0.0031 16.6 0.0 0.38 9.7 0.0 2.9 2 1 1 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EXF81918.1 - 0.0044 17.0 0.0 0.016 15.2 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Methyltransf_2 PF00891.13 EXF81919.1 - 1.4e-25 89.8 0.0 2.1e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase FeoC PF09012.5 EXF81919.1 - 0.048 13.3 0.2 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 FeoC like transcriptional regulator HsbA PF12296.3 EXF81920.1 - 2.7e-22 78.9 13.2 2.7e-22 78.9 9.1 2.1 2 0 0 2 2 2 1 Hydrophobic surface binding protein A AAA_12 PF13087.1 EXF81921.1 - 2.1e-40 138.2 0.0 5.2e-40 136.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EXF81921.1 - 2.7e-36 124.6 0.0 2.1e-13 50.5 0.0 5.5 5 0 0 5 5 5 3 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.1 EXF81921.1 - 1.1e-35 123.3 16.5 2.8e-31 108.9 0.0 5.4 4 1 0 4 4 4 2 AAA domain AAA_19 PF13245.1 EXF81921.1 - 2.8e-18 65.4 1.8 2e-09 37.0 0.0 4.8 4 0 0 4 4 4 3 Part of AAA domain AAA_30 PF13604.1 EXF81921.1 - 8.4e-14 51.6 1.7 1.8e-05 24.4 0.0 5.2 4 1 0 4 4 4 3 AAA domain AAA_17 PF13207.1 EXF81921.1 - 1.7e-10 41.7 3.2 0.12 13.1 0.1 5.7 5 0 0 5 5 4 3 AAA domain AAA_22 PF13401.1 EXF81921.1 - 1.3e-09 38.3 6.3 0.2 11.7 0.4 6.9 5 3 1 6 6 6 3 AAA domain AAA_5 PF07728.9 EXF81921.1 - 3.8e-09 36.3 0.3 0.063 13.0 0.0 4.7 4 0 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EXF81921.1 - 7e-09 35.9 6.7 0.019 14.9 0.0 5.3 5 1 0 5 5 4 3 AAA ATPase domain Mg_chelatase PF01078.16 EXF81921.1 - 1.3e-06 27.7 0.1 0.24 10.5 0.0 3.8 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EXF81921.1 - 8.5e-06 25.3 0.0 0.43 9.9 0.0 3.9 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_24 PF13479.1 EXF81921.1 - 2.8e-05 23.8 4.8 0.59 9.6 0.0 4.4 3 2 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 EXF81921.1 - 4.6e-05 23.5 0.0 3.1 8.0 0.0 3.7 3 0 0 3 3 3 2 RNA helicase Torsin PF06309.6 EXF81921.1 - 5.4e-05 23.0 0.0 2.3 8.1 0.0 3.8 3 0 0 3 3 3 2 Torsin AAA_10 PF12846.2 EXF81921.1 - 0.00019 20.9 0.7 10 5.4 0.0 5.5 4 1 1 5 5 5 0 AAA-like domain AAA_25 PF13481.1 EXF81921.1 - 0.0013 18.1 1.2 0.71 9.2 0.0 3.9 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EXF81921.1 - 0.0018 18.5 14.9 1.4 9.2 0.0 5.8 6 0 0 6 6 5 2 AAA domain Helicase_RecD PF05127.9 EXF81921.1 - 0.002 17.8 0.5 0.24 10.9 0.0 3.3 3 0 0 3 3 2 1 Helicase AAA_33 PF13671.1 EXF81921.1 - 0.0048 16.7 9.9 1.2 9.0 0.0 4.8 5 0 0 5 5 4 2 AAA domain DUF2075 PF09848.4 EXF81921.1 - 0.036 13.0 10.9 0.065 12.1 0.0 5.1 5 1 0 5 5 5 0 Uncharacterized conserved protein (DUF2075) SRP54 PF00448.17 EXF81921.1 - 0.17 11.2 2.6 7.7 5.9 0.0 3.5 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain TPD PF14811.1 EXF81921.1 - 0.42 10.1 2.8 1.8 8.0 1.9 2.1 1 0 0 1 1 1 0 Protein of unknown function TPD sequence-motif CATSPERD PF15020.1 EXF81921.1 - 0.71 7.8 0.0 1.1 7.1 0.0 1.2 1 0 0 1 1 1 0 Cation channel sperm-associated protein subunit delta Lysine_decarbox PF03641.9 EXF81923.1 - 1.2e-29 102.7 0.0 1.6e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase RNase_T PF00929.19 EXF81924.1 - 7.4e-14 52.3 0.0 2.3e-09 37.7 0.0 2.3 2 0 0 2 2 2 2 Exonuclease Ly49 PF08391.5 EXF81924.1 - 0.11 12.6 0.2 0.5 10.5 0.3 2.0 2 1 0 2 2 2 0 Ly49-like protein, N-terminal region F-box-like PF12937.2 EXF81925.1 - 9.9e-13 47.5 0.4 2.2e-12 46.5 0.3 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EXF81925.1 - 7.9e-09 34.9 9.8 0.018 14.6 0.0 6.3 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EXF81925.1 - 8.8e-09 34.9 13.6 0.0022 17.7 0.0 5.4 4 2 2 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 EXF81925.1 - 1.5e-07 30.7 21.3 1.1 9.4 0.0 10.8 11 1 0 11 11 11 2 Leucine Rich repeat LRR_1 PF00560.28 EXF81925.1 - 4.3e-07 29.0 22.7 12 6.3 0.0 10.2 9 2 0 9 9 9 1 Leucine Rich Repeat F-box PF00646.28 EXF81925.1 - 0.00013 21.5 2.2 0.00015 21.3 0.1 2.1 2 0 0 2 2 2 1 F-box domain DUF717 PF05338.7 EXF81925.1 - 0.035 14.0 0.0 1.4 8.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF717) LRR_7 PF13504.1 EXF81925.1 - 0.2 11.9 25.9 7.4 7.2 0.0 8.6 10 0 0 10 10 10 0 Leucine rich repeat Ste50p-SAM PF09235.5 EXF81925.1 - 8.3 6.5 14.3 20 5.3 0.0 6.1 4 1 3 7 7 7 0 Ste50p, sterile alpha motif Chalcone PF02431.10 EXF81927.1 - 3.4e-59 199.6 0.0 4.5e-59 199.2 0.0 1.2 1 0 0 1 1 1 1 Chalcone-flavanone isomerase DUF3498 PF12004.3 EXF81927.1 - 0.045 12.8 0.7 0.072 12.2 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Glutaredoxin PF00462.19 EXF81928.1 - 8e-19 67.3 0.0 1.2e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_9 PF14595.1 EXF81928.1 - 8.8e-05 22.0 0.0 0.00011 21.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.15 EXF81928.1 - 0.0018 17.8 0.0 0.002 17.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EXF81928.1 - 0.0021 18.2 0.1 0.0033 17.6 0.1 1.6 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.9 EXF81928.1 - 0.0025 18.0 0.0 0.0034 17.6 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) TraF PF13728.1 EXF81928.1 - 0.0029 17.1 0.0 0.0033 16.9 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein DSBA PF01323.15 EXF81928.1 - 0.0031 17.1 0.2 0.0076 15.8 0.1 1.6 1 1 1 2 2 2 1 DSBA-like thioredoxin domain GST_N_3 PF13417.1 EXF81928.1 - 0.0051 17.0 0.0 0.0084 16.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glyco_transf_49 PF13896.1 EXF81928.1 - 0.042 12.9 0.0 0.054 12.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl-transferase for dystroglycan Thioredoxin_3 PF13192.1 EXF81928.1 - 0.054 13.3 0.0 0.075 12.8 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin domain Redoxin PF08534.5 EXF81928.1 - 0.07 12.6 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 Redoxin Thioredoxin_7 PF13899.1 EXF81928.1 - 0.076 13.0 0.1 0.12 12.4 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin-like BAG PF02179.11 EXF81929.1 - 8.2e-20 70.6 1.9 1.5e-19 69.8 1.3 1.4 1 0 0 1 1 1 1 BAG domain ubiquitin PF00240.18 EXF81929.1 - 0.00022 20.5 0.0 0.00066 19.0 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_L13 PF00572.13 EXF81930.1 - 1.4e-27 96.3 0.3 2.3e-27 95.5 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L13 DSBA PF01323.15 EXF81930.1 - 0.029 13.9 0.1 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Swi5 PF07061.6 EXF81931.1 - 9.6e-20 70.1 0.0 1.1e-19 70.0 0.0 1.0 1 0 0 1 1 1 1 Swi5 SCP-1 PF05483.7 EXF81931.1 - 0.075 10.8 0.3 0.078 10.7 0.2 1.0 1 0 0 1 1 1 0 Synaptonemal complex protein 1 (SCP-1) Latarcin PF10279.4 EXF81931.1 - 0.098 12.8 0.1 0.12 12.5 0.1 1.1 1 0 0 1 1 1 0 Latarcin precursor Ank_2 PF12796.2 EXF81932.1 - 5.2e-37 126.0 0.4 8.9e-14 51.6 0.0 5.1 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EXF81932.1 - 1.4e-22 78.3 13.8 9.3e-05 22.0 0.1 9.0 9 0 0 9 9 9 7 Ankyrin repeat Ank_3 PF13606.1 EXF81932.1 - 6.2e-22 75.5 4.9 0.0017 18.4 0.0 9.0 9 0 0 9 9 9 7 Ankyrin repeat Ank_4 PF13637.1 EXF81932.1 - 1.5e-18 66.8 1.6 0.0024 18.3 0.0 6.8 7 1 0 7 7 7 5 Ankyrin repeats (many copies) Clr5 PF14420.1 EXF81932.1 - 3.4e-14 52.4 2.3 7e-14 51.4 1.6 1.6 1 0 0 1 1 1 1 Clr5 domain Ank_5 PF13857.1 EXF81932.1 - 2.4e-13 49.8 2.9 0.046 13.9 0.0 6.7 6 0 0 6 6 6 4 Ankyrin repeats (many copies) Abhydrolase_6 PF12697.2 EXF81933.1 - 4.4e-31 108.5 0.0 5.8e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF81933.1 - 1.5e-20 73.7 0.1 5.8e-18 65.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF81933.1 - 2.9e-13 49.8 0.0 1.7e-12 47.3 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EXF81933.1 - 3.1e-05 22.5 0.0 5.3e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 EXF81933.1 - 3.7e-05 23.5 0.0 7.1e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EXF81933.1 - 0.037 13.2 0.3 6.9 5.8 0.0 2.6 2 1 0 2 2 2 0 Prolyl oligopeptidase family COesterase PF00135.23 EXF81935.1 - 2.2e-80 270.9 0.0 3e-80 270.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF81935.1 - 2.2e-05 24.1 0.2 5.5e-05 22.8 0.0 1.8 3 0 0 3 3 3 1 alpha/beta hydrolase fold Epimerase PF01370.16 EXF81936.1 - 1.2e-09 37.9 0.0 1.4e-09 37.7 0.0 1.0 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EXF81936.1 - 1e-07 30.9 0.0 1.2e-07 30.7 0.0 1.0 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EXF81936.1 - 1.5e-07 31.6 0.0 1.9e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EXF81936.1 - 7.1e-07 29.2 0.0 7.6e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.7 EXF81936.1 - 9.5e-06 24.7 0.1 0.0001 21.3 0.0 1.9 1 1 0 1 1 1 1 Male sterility protein KR PF08659.5 EXF81936.1 - 0.00028 20.6 0.0 0.00032 20.4 0.0 1.2 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.12 EXF81936.1 - 0.0022 18.3 0.0 0.003 17.9 0.0 1.3 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Polysacc_synt_2 PF02719.10 EXF81936.1 - 0.0036 16.2 0.0 0.004 16.1 0.0 1.0 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EXF81936.1 - 0.016 14.5 0.0 0.018 14.3 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Saccharop_dh PF03435.13 EXF81936.1 - 0.041 12.8 0.0 0.048 12.6 0.0 1.0 1 0 0 1 1 1 0 Saccharopine dehydrogenase RmlD_sub_bind PF04321.12 EXF81936.1 - 0.055 12.3 0.0 0.062 12.1 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DapB_N PF01113.15 EXF81936.1 - 0.11 12.3 0.0 0.17 11.8 0.0 1.3 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short_C2 PF13561.1 EXF81936.1 - 0.11 12.2 0.1 0.12 12.0 0.1 1.2 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EXF81937.1 - 0.036 13.5 0.0 0.059 12.8 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EXF81938.1 - 6.5e-18 65.2 0.5 2e-17 63.6 0.2 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EXF81938.1 - 1.7e-07 31.1 0.2 4e-07 29.8 0.1 1.5 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EXF81938.1 - 8.9e-05 22.5 0.1 0.00019 21.5 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF81938.1 - 0.00035 20.0 0.0 0.00081 18.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EXF81938.1 - 0.0063 16.3 0.0 0.0093 15.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Eno-Rase_NADH_b PF12242.3 EXF81938.1 - 0.068 12.9 0.0 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Methyltransf_23 PF13489.1 EXF81939.1 - 1.2e-11 44.5 0.0 1.6e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF81939.1 - 4.6e-08 32.7 0.0 6.4e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF81939.1 - 1.2e-07 32.1 0.0 2.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF81939.1 - 1.6e-06 28.6 0.0 2.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF81939.1 - 3.6e-06 27.3 0.0 5e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF81939.1 - 6.2e-05 22.9 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF81939.1 - 0.00073 18.7 0.0 0.00096 18.3 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EXF81939.1 - 0.0031 17.8 0.0 0.0046 17.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.7 EXF81939.1 - 0.012 15.6 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase FkbM domain Methyltransf_24 PF13578.1 EXF81939.1 - 0.013 16.3 0.0 0.018 15.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.15 EXF81939.1 - 0.015 14.3 0.0 0.023 13.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_28 PF02636.12 EXF81939.1 - 0.058 12.7 0.0 0.08 12.3 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PCMT PF01135.14 EXF81939.1 - 0.067 12.7 0.0 0.094 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PRMT5 PF05185.11 EXF81939.1 - 0.16 10.8 0.0 0.21 10.4 0.0 1.1 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase CN_hydrolase PF00795.17 EXF81940.1 - 2.2e-38 131.5 0.0 2.8e-38 131.1 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FAD_binding_4 PF01565.18 EXF81941.1 - 2.5e-17 62.6 0.0 5.2e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain Sugar_tr PF00083.19 EXF81943.1 - 3e-112 375.5 27.1 3.7e-112 375.1 18.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF81943.1 - 4.2e-24 84.9 29.0 7.8e-24 84.0 13.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily EMP70 PF02990.11 EXF81943.1 - 0.54 8.6 10.9 0.014 13.9 2.5 1.9 2 0 0 2 2 2 0 Endomembrane protein 70 DUF1201 PF06716.6 EXF81943.1 - 6 6.7 10.8 0.53 10.1 3.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1201) Sulfatase PF00884.18 EXF81944.1 - 1.6e-61 208.2 0.3 2.1e-61 207.8 0.2 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EXF81944.1 - 2.7e-10 40.1 4.5 8e-10 38.5 3.1 1.7 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF229 PF02995.12 EXF81944.1 - 0.0006 18.3 0.0 0.0022 16.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF229) Metalloenzyme PF01676.13 EXF81944.1 - 0.085 12.2 0.0 0.27 10.5 0.0 1.8 2 1 0 2 2 2 0 Metalloenzyme superfamily Zn_clus PF00172.13 EXF81945.1 - 5.8e-14 51.7 25.9 1.4e-07 31.3 8.8 2.6 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF81945.1 - 4e-10 38.9 0.1 7.5e-10 38.1 0.1 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.16 EXF81947.1 - 6.9e-52 176.2 0.0 9.1e-52 175.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF81947.1 - 1.6e-43 148.8 0.0 2.5e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF81947.1 - 2.3e-15 56.2 0.1 5e-15 55.2 0.1 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain MFS_1 PF07690.11 EXF81948.1 - 2.3e-45 154.8 53.5 8.3e-45 153.0 35.1 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF81948.1 - 5.2e-12 45.0 28.2 1.6e-10 40.2 4.6 3.0 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EXF81948.1 - 1.9e-09 36.2 18.8 5.1e-09 34.8 13.0 1.6 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4131 PF13567.1 EXF81948.1 - 0.16 11.3 17.0 0.6 9.5 1.6 4.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4131) Fungal_trans PF04082.13 EXF81949.1 - 5.6e-15 54.9 0.0 8.2e-15 54.3 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF81949.1 - 1.2e-08 34.6 9.6 2.2e-08 33.8 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GMC_oxred_N PF00732.14 EXF81950.1 - 7.6e-65 218.9 0.0 1e-64 218.5 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF81950.1 - 2.4e-32 112.2 0.0 4.2e-32 111.4 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EXF81950.1 - 0.00021 20.3 0.2 0.00035 19.6 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EXF81950.1 - 0.0098 14.7 2.2 2.3 6.9 0.9 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.9 EXF81950.1 - 0.078 12.8 0.1 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF81950.1 - 0.38 9.7 1.9 0.39 9.7 0.1 1.9 2 0 0 2 2 2 0 Thi4 family Sugar_tr PF00083.19 EXF81951.1 - 3.5e-107 358.7 23.2 8.9e-107 357.4 16.1 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF81951.1 - 3.8e-22 78.4 52.8 8.6e-17 60.8 17.6 2.8 1 1 2 3 3 3 2 Major Facilitator Superfamily DUF910 PF06014.6 EXF81951.1 - 0.017 15.0 0.0 0.039 13.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF910) DUF2207 PF09972.4 EXF81951.1 - 0.81 8.1 7.0 1.5 7.3 0.0 2.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF89 PF01937.14 EXF81952.1 - 1.8e-133 444.7 0.1 2.1e-133 444.5 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 Lustrin_cystein PF14625.1 EXF81954.1 - 0.086 12.9 9.2 2.8 8.0 2.2 2.5 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain Abi PF02517.11 EXF81956.1 - 8.4 6.6 9.0 8.2 6.6 4.3 2.4 2 1 0 2 2 2 0 CAAX protease self-immunity HET PF06985.6 EXF81957.1 - 7.7e-24 84.4 0.2 1.5e-23 83.5 0.1 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 EXF81958.1 - 2.6e-36 125.0 25.7 2.6e-36 125.0 17.8 1.6 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF3390 PF11870.3 EXF81958.1 - 0.12 12.3 0.4 0.3 11.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3390) Fungal_trans_2 PF11951.3 EXF81959.1 - 3.3e-07 29.2 2.4 0.00067 18.3 0.0 2.2 2 1 0 2 2 2 2 Fungal specific transcription factor domain Transp_cyt_pur PF02133.10 EXF81960.1 - 1.2e-11 43.8 22.7 1.2e-11 43.8 15.7 1.9 1 1 1 2 2 2 1 Permease for cytosine/purines, uracil, thiamine, allantoin CFEM PF05730.6 EXF81961.1 - 4.7e-10 39.1 11.0 1.2e-09 37.8 7.6 1.7 1 0 0 1 1 1 1 CFEM domain Peptidase_M43 PF05572.8 EXF81962.1 - 4.4e-08 32.8 0.2 8.7e-08 31.9 0.1 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_2 PF13574.1 EXF81962.1 - 0.005 16.9 0.1 0.011 15.7 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EXF81962.1 - 0.034 14.0 0.3 0.085 12.7 0.2 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EXF81962.1 - 0.05 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like BAR_2 PF10455.4 EXF81963.1 - 0.17 10.7 0.6 11 4.8 0.1 2.2 2 0 0 2 2 2 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Sod_Fe_C PF02777.13 EXF81964.1 - 3.5e-31 107.1 0.1 6.2e-31 106.3 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EXF81964.1 - 2.7e-30 104.4 5.0 2.7e-30 104.4 3.5 2.1 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Lectin_C PF00059.16 EXF81966.1 - 0.073 13.7 1.1 0.45 11.1 0.5 2.1 2 0 0 2 2 2 0 Lectin C-type domain MRJP PF03022.11 EXF81967.1 - 1.3e-32 113.2 0.0 1.6e-32 112.8 0.0 1.1 1 0 0 1 1 1 1 Major royal jelly protein SGL PF08450.7 EXF81967.1 - 0.00071 19.0 0.0 0.0051 16.2 0.0 2.1 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EXF81967.1 - 0.071 13.0 0.2 29 4.8 0.0 3.3 3 0 0 3 3 3 0 NHL repeat Myco_19_kDa PF05481.7 EXF81968.1 - 0.058 13.2 0.4 0.069 12.9 0.3 1.1 1 0 0 1 1 1 0 Mycobacterium 19 kDa lipoprotein antigen Peptidase_M20 PF01546.23 EXF81969.1 - 1.5e-22 80.0 0.1 2.1e-22 79.5 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EXF81969.1 - 5e-18 64.8 0.0 7.8e-18 64.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EXF81969.1 - 0.00036 20.3 0.1 0.00053 19.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 FMO-like PF00743.14 EXF81970.1 - 4.9e-52 176.8 0.0 4.8e-49 166.9 0.0 2.2 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EXF81970.1 - 1.9e-23 83.5 0.0 6.3e-23 81.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF81970.1 - 1.3e-08 34.6 0.0 3.2e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EXF81970.1 - 2.1e-06 26.9 0.5 1.8e-05 23.8 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EXF81970.1 - 6.9e-06 26.0 0.0 2.9e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF81970.1 - 7.2e-06 25.8 0.1 0.00096 18.9 0.0 2.8 2 1 0 2 2 2 1 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 EXF81970.1 - 0.0036 16.4 0.0 0.32 10.1 0.0 2.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EXF81970.1 - 0.0037 17.3 0.0 0.23 11.5 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 EXF81970.1 - 0.059 12.4 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Thi4 family DAO PF01266.19 EXF81970.1 - 0.069 12.0 0.0 1 8.2 0.0 2.3 1 1 1 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EXF81970.1 - 0.074 13.3 0.0 25 5.1 0.0 2.9 2 1 0 2 2 2 0 Putative NAD(P)-binding TauD PF02668.11 EXF81971.1 - 3.4e-29 102.3 0.4 4.5e-29 101.8 0.3 1.2 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EXF81971.1 - 0.064 12.1 0.0 0.097 11.5 0.0 1.2 1 0 0 1 1 1 0 CsiD ABM PF03992.11 EXF81972.1 - 0.006 16.5 0.5 0.072 13.1 0.0 2.7 3 1 0 3 3 3 1 Antibiotic biosynthesis monooxygenase Dabb PF07876.7 EXF81972.1 - 0.043 14.2 0.0 1.3 9.4 0.0 2.7 1 1 1 2 2 2 0 Stress responsive A/B Barrel Domain NIPSNAP PF07978.8 EXF81972.1 - 0.06 13.3 0.4 0.34 10.9 0.1 2.0 2 0 0 2 2 2 0 NIPSNAP FA_hydroxylase PF04116.8 EXF81973.1 - 1.3e-15 57.7 18.4 1.3e-15 57.7 12.7 2.2 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF605 PF04652.11 EXF81974.1 - 0.11 11.8 3.5 0.13 11.6 2.4 1.0 1 0 0 1 1 1 0 Vta1 like MUG113 PF13455.1 EXF81975.1 - 5.9e-26 90.7 0.0 1.2e-25 89.7 0.0 1.5 1 0 0 1 1 1 1 Meiotically up-regulated gene 113 T5orf172 PF10544.4 EXF81975.1 - 2.3e-19 69.6 0.0 7.6e-19 67.9 0.0 1.9 1 0 0 1 1 1 1 T5orf172 domain PAT1 PF09770.4 EXF81975.1 - 0.014 13.6 10.1 0.018 13.2 7.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DEAD PF00270.24 EXF81976.1 - 1.3e-36 125.6 0.1 2.2e-36 124.9 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF81976.1 - 6.6e-24 83.5 0.0 6.1e-23 80.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EXF81976.1 - 5.6e-05 23.0 0.1 0.00016 21.5 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EXF81976.1 - 0.02 13.9 0.2 0.16 11.0 0.1 2.1 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Rpr2 PF04032.11 EXF81977.1 - 2.7e-21 75.2 0.8 3.6e-21 74.8 0.5 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain RepB PF07506.6 EXF81977.1 - 0.12 12.1 0.8 0.29 10.9 0.6 1.6 1 1 0 1 1 1 0 RepB plasmid partitioning protein Pyridoxal_deC PF00282.14 EXF81978.1 - 2.1e-64 217.3 0.0 2.9e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EXF81978.1 - 0.00015 20.6 0.0 0.00025 19.9 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V OPT PF03169.10 EXF81979.1 - 2.3e-186 620.9 53.6 2.7e-186 620.7 37.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein EIAV_GP90 PF00971.13 EXF81979.1 - 0.47 8.8 4.9 0.31 9.4 0.1 2.2 2 0 0 2 2 2 0 EIAV coat protein, gp90 eIF3_subunit PF08597.5 EXF81980.1 - 0.0051 16.3 2.3 0.0051 16.3 1.6 1.7 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit CRISPR_Cse2 PF09485.5 EXF81980.1 - 0.11 12.5 0.1 0.11 12.5 0.1 1.7 2 0 0 2 2 2 0 CRISPR-associated protein Cse2 (CRISPR_cse2) BAF1_ABF1 PF04684.8 EXF81981.1 - 0.0028 16.5 7.2 0.0028 16.5 5.0 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor DUF822 PF05687.8 EXF81981.1 - 0.12 12.7 6.9 0.16 12.3 4.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF822) Med15 PF09606.5 EXF81981.1 - 0.85 7.7 23.7 0.93 7.6 16.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Lin-8 PF03353.10 EXF81981.1 - 1.1 8.4 5.2 1.3 8.2 3.6 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Activator_LAG-3 PF11498.3 EXF81981.1 - 2 7.1 21.1 2.3 6.8 14.6 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 p450 PF00067.17 EXF81983.1 - 6.9e-46 156.7 0.0 1.1e-44 152.7 0.0 2.0 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EXF81984.1 - 1.9e-38 132.0 36.7 2.8e-37 128.2 14.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF81984.1 - 3.3e-07 29.2 2.3 3.3e-07 29.2 1.6 1.9 2 1 0 2 2 2 1 Sugar (and other) transporter adh_short PF00106.20 EXF81985.1 - 2.6e-18 66.5 0.5 5.8e-18 65.3 0.3 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF81985.1 - 2.2e-08 34.0 1.4 6.2e-08 32.5 1.0 1.8 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF81985.1 - 3.4e-05 23.4 0.5 0.00054 19.4 0.3 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EXF81985.1 - 7.3e-05 22.6 0.0 0.00011 22.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF3446 PF11928.3 EXF81985.1 - 0.0039 17.3 4.9 0.0045 17.1 2.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3446) Eno-Rase_NADH_b PF12242.3 EXF81985.1 - 0.018 14.8 0.1 0.049 13.4 0.0 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase adh_short PF00106.20 EXF81986.1 - 1e-31 110.0 0.9 1e-31 110.0 0.6 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF81986.1 - 2e-17 63.8 0.0 2.8e-17 63.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF81986.1 - 1.5e-10 41.0 2.0 2.5e-10 40.3 0.2 1.8 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.1 EXF81986.1 - 1.1e-07 32.0 0.1 2.2e-07 31.0 0.1 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF81986.1 - 0.00041 19.8 0.1 0.0013 18.2 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EXF81986.1 - 0.00081 18.6 0.0 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) UPF0020 PF01170.13 EXF81988.1 - 0.061 12.8 0.0 0.095 12.2 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PI3_PI4_kinase PF00454.22 EXF81989.1 - 2.2e-44 151.6 0.0 4.7e-44 150.6 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EXF81989.1 - 3.4e-12 45.5 0.1 1.3e-11 43.7 0.1 2.1 1 0 0 1 1 1 1 FATC domain Cullin PF00888.17 EXF81990.1 - 3.7e-124 415.4 0.2 5.7e-124 414.8 0.1 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EXF81990.1 - 4.9e-26 90.3 0.6 1.4e-25 88.9 0.4 1.8 1 0 0 1 1 1 1 Cullin protein neddylation domain Ribosomal_L10 PF00466.15 EXF81991.1 - 5.1e-21 74.4 0.0 7.4e-21 73.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 U1snRNP70_N PF12220.3 EXF81992.1 - 1.5e-27 95.7 3.6 1.5e-27 95.7 2.5 1.7 2 0 0 2 2 2 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EXF81992.1 - 9.2e-12 44.4 0.1 3.8e-10 39.2 0.1 2.9 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF81992.1 - 5.4e-08 32.7 0.0 1.9e-07 30.9 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF81992.1 - 0.00035 20.3 0.0 0.031 14.1 0.1 2.5 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) L51_S25_CI-B8 PF05047.11 EXF81993.1 - 1.2e-16 60.1 0.0 2.6e-16 59.0 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain TIM PF00121.13 EXF81994.1 - 3.2e-87 291.6 0.6 3.6e-87 291.4 0.4 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase zf-C2H2_4 PF13894.1 EXF81996.1 - 0.0016 18.6 10.1 0.038 14.3 0.1 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF81996.1 - 0.012 15.8 3.7 0.64 10.4 0.0 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Zn_clus PF00172.13 EXF81997.1 - 0.00012 21.9 4.6 0.0066 16.3 1.5 2.5 2 0 0 2 2 2 2 Fungal Zn(2)-Cys(6) binuclear cluster domain Zn_clus PF00172.13 EXF81999.1 - 0.00038 20.3 12.2 0.00066 19.5 8.4 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain SET PF00856.23 EXF82001.1 - 1.4e-09 38.4 0.4 5.4e-07 30.0 0.0 2.9 3 0 0 3 3 3 2 SET domain TPR_11 PF13414.1 EXF82001.1 - 1.3e-06 27.9 1.8 1.3e-06 27.9 1.3 3.5 4 0 0 4 4 4 1 TPR repeat TPR_2 PF07719.12 EXF82001.1 - 0.00017 21.2 11.3 0.053 13.4 0.1 4.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EXF82001.1 - 0.32 11.7 11.1 1.4 9.7 1.6 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.1 EXF82001.1 - 2.3 8.4 5.6 0.55 10.4 0.1 2.5 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation TPR_12 PF13424.1 EXF82001.1 - 7.1 6.6 12.5 4.6 7.2 0.6 3.5 4 0 0 4 4 4 0 Tetratricopeptide repeat KTI12 PF08433.5 EXF82003.1 - 2.6e-66 223.5 0.0 6e-66 222.4 0.0 1.6 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_18 PF13238.1 EXF82003.1 - 6.3e-05 23.2 0.0 0.002 18.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EXF82003.1 - 0.00012 22.8 1.0 0.00071 20.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EXF82003.1 - 0.00032 20.5 0.3 0.00077 19.3 0.2 1.7 1 0 0 1 1 1 1 AAA domain CPT PF07931.7 EXF82003.1 - 0.023 14.3 0.1 0.064 12.8 0.1 1.6 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.1 EXF82003.1 - 0.068 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EXF82003.1 - 0.083 12.7 0.0 0.54 10.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain Orthopox_A36R PF05950.6 EXF82003.1 - 0.1 12.5 0.1 0.17 11.8 0.1 1.3 1 0 0 1 1 1 0 Orthopoxvirus A36R protein PalH PF08733.5 EXF82005.1 - 1.1e-100 336.8 1.0 1.6e-100 336.3 0.7 1.1 1 0 0 1 1 1 1 PalH/RIM21 TRAM_LAG1_CLN8 PF03798.11 EXF82006.1 - 1.6e-33 115.9 19.5 2.7e-33 115.2 13.5 1.4 1 0 0 1 1 1 1 TLC domain TRAM1 PF08390.6 EXF82006.1 - 7.6e-24 82.9 1.7 1.5e-23 82.0 0.0 2.3 3 0 0 3 3 3 1 TRAM1-like protein ABC_tran PF00005.22 EXF82007.1 - 2.8e-32 111.8 0.1 1.3e-31 109.6 0.0 2.1 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 EXF82007.1 - 2.8e-23 82.6 8.9 2.8e-23 82.6 6.2 2.4 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 EXF82007.1 - 2.8e-06 26.7 0.2 2.4e-05 23.6 0.1 2.2 2 1 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EXF82007.1 - 0.0012 18.9 0.0 0.097 12.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EXF82007.1 - 0.0032 16.6 0.0 0.0068 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EXF82007.1 - 0.014 14.8 0.2 0.049 13.1 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain 4HB_MCP_1 PF12729.2 EXF82007.1 - 0.023 14.0 1.2 0.045 13.1 0.8 1.4 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction SbcCD_C PF13558.1 EXF82007.1 - 0.04 13.8 0.1 0.33 10.9 0.1 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit DND1_DSRM PF14709.1 EXF82009.1 - 0.00016 21.8 0.1 0.0004 20.6 0.1 1.7 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 dsrm PF00035.20 EXF82009.1 - 0.0034 17.9 0.0 0.0077 16.7 0.0 1.6 1 0 0 1 1 1 1 Double-stranded RNA binding motif NTP_transferase PF00483.18 EXF82010.1 - 2.6e-48 164.4 0.0 6.3e-48 163.2 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep PF00132.19 EXF82010.1 - 7.1e-17 60.0 12.8 4.1e-10 38.7 1.1 4.1 1 1 3 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EXF82010.1 - 6.5e-12 45.8 0.0 9.7e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EXF82010.1 - 8.7e-08 31.5 4.0 3.4e-06 26.4 0.7 3.1 3 0 0 3 3 3 1 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.14 EXF82010.1 - 0.0066 16.0 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase IspD PF01128.14 EXF82010.1 - 0.0067 15.9 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase FGGY_C PF02782.11 EXF82011.1 - 5.9e-72 241.4 0.6 1.1e-71 240.6 0.4 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FGGY_N PF00370.16 EXF82011.1 - 4.1e-64 216.2 0.0 5.6e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain DUF1612 PF07756.7 EXF82011.1 - 0.062 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1612) Ion_trans_2 PF07885.11 EXF82014.1 - 6.4e-32 109.1 24.0 4.1e-19 68.0 1.4 3.1 3 1 0 3 3 3 2 Ion channel Ion_trans PF00520.26 EXF82014.1 - 0.01 15.0 1.6 0.01 15.0 1.1 2.9 2 1 0 2 2 2 0 Ion transport protein zf-RING_4 PF14570.1 EXF82016.1 - 1.6e-19 69.2 12.2 2.8e-19 68.4 8.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.17 EXF82016.1 - 7.5e-11 41.5 0.1 3.3e-10 39.4 0.0 2.1 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 EXF82016.1 - 7.7e-07 28.6 6.9 1.4e-06 27.8 4.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RRM_6 PF14259.1 EXF82016.1 - 2.3e-06 27.4 0.0 6.2e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Rtf2 PF04641.7 EXF82016.1 - 3.1e-05 23.3 4.1 6.6e-05 22.2 2.8 1.5 1 0 0 1 1 1 1 Rtf2 RING-finger RRM_5 PF13893.1 EXF82016.1 - 4.3e-05 23.2 0.0 9.9e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.1 EXF82016.1 - 0.00032 20.4 9.0 0.00032 20.4 6.2 1.7 2 0 0 2 2 1 1 Ring finger domain SET_assoc PF11767.3 EXF82016.1 - 0.0036 16.5 0.0 0.0082 15.4 0.0 1.5 1 0 0 1 1 1 1 Histone lysine methyltransferase SET associated FYVE_2 PF02318.11 EXF82016.1 - 0.0089 15.9 4.4 0.0089 15.9 3.1 2.5 1 1 1 2 2 2 1 FYVE-type zinc finger Nup35_RRM_2 PF14605.1 EXF82016.1 - 0.012 15.4 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif FYVE PF01363.16 EXF82016.1 - 0.023 14.5 4.4 0.057 13.3 3.0 1.6 1 0 0 1 1 1 0 FYVE zinc finger Baculo_IE-1 PF05290.6 EXF82016.1 - 0.029 14.1 5.2 0.052 13.2 3.6 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.20 EXF82016.1 - 0.047 13.3 10.3 0.1 12.2 7.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.1 EXF82016.1 - 0.24 11.1 5.8 0.17 11.6 2.5 1.9 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-C3HC4_2 PF13923.1 EXF82016.1 - 0.4 10.7 10.8 0.91 9.6 7.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EXF82016.1 - 4.2 6.9 12.4 1.1 8.9 3.4 2.7 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Complex1_30kDa PF00329.14 EXF82017.1 - 3e-35 120.5 0.0 4.3e-35 120.0 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit DUF2087 PF09860.4 EXF82017.1 - 0.093 12.4 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2087) ASCH PF04266.9 EXF82019.1 - 0.038 14.3 0.0 0.12 12.7 0.0 1.9 2 0 0 2 2 2 0 ASCH domain CobT PF06213.7 EXF82020.1 - 0.0064 15.6 5.5 0.0064 15.6 3.8 2.1 2 0 0 2 2 2 1 Cobalamin biosynthesis protein CobT TFIIA PF03153.8 EXF82020.1 - 0.02 14.7 4.4 0.037 13.9 3.1 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4366 PF14283.1 EXF82020.1 - 0.033 13.6 2.4 0.062 12.7 1.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Nop14 PF04147.7 EXF82020.1 - 0.15 9.9 11.9 0.25 9.2 8.2 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.4 EXF82020.1 - 3.7 6.1 21.1 0.047 12.4 7.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) TRAP_alpha PF03896.11 EXF82020.1 - 7.8 5.4 12.1 0.73 8.7 4.9 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Peptidase_S10 PF00450.17 EXF82021.1 - 4.2e-75 253.4 0.2 8.2e-75 252.5 0.2 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase Fapy_DNA_glyco PF01149.19 EXF82022.1 - 5.8e-22 78.2 0.4 1.8e-21 76.6 0.0 1.9 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain H2TH PF06831.9 EXF82022.1 - 4.8e-19 67.8 0.0 9.7e-19 66.9 0.0 1.5 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Roughex PF06020.6 EXF82022.1 - 0.82 8.2 6.8 8.5 4.9 4.7 2.0 2 0 0 2 2 2 0 Drosophila roughex protein Cupin_2 PF07883.6 EXF82023.1 - 9.8e-14 50.6 0.0 1.5e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EXF82023.1 - 0.00032 20.3 0.0 0.00044 19.9 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EXF82023.1 - 0.00084 18.7 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Cupin CENP-C_C PF11699.3 EXF82023.1 - 0.0025 17.7 0.0 0.0036 17.2 0.0 1.3 1 0 0 1 1 1 1 Mif2/CENP-C like Cupin_6 PF12852.2 EXF82023.1 - 0.02 14.5 0.0 0.025 14.2 0.0 1.2 1 0 0 1 1 1 0 Cupin MannoseP_isomer PF01050.13 EXF82023.1 - 0.045 13.3 0.0 0.06 12.9 0.0 1.2 1 0 0 1 1 1 0 Mannose-6-phosphate isomerase PAS_9 PF13426.1 EXF82024.1 - 2.1e-18 66.5 0.0 3.3e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EXF82024.1 - 0.0011 18.7 0.0 0.037 13.8 0.0 2.3 1 1 0 1 1 1 1 PAS fold PAS_3 PF08447.6 EXF82024.1 - 0.14 12.3 0.1 4.1 7.5 0.0 2.3 1 1 0 1 1 1 0 PAS fold Pyridox_oxidase PF01243.15 EXF82025.1 - 0.0026 17.7 0.0 0.13 12.2 0.0 2.6 3 0 0 3 3 3 1 Pyridoxamine 5'-phosphate oxidase FAD_binding_6 PF00970.19 EXF82025.1 - 0.0043 17.1 0.0 0.33 11.0 0.0 2.3 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain VirB3 PF05101.8 EXF82026.1 - 4.1 7.4 8.5 0.078 12.9 0.8 1.9 2 0 0 2 2 2 0 Type IV secretory pathway, VirB3-like protein Pkinase PF00069.20 EXF82028.1 - 0.00011 21.3 0.0 0.00027 20.1 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Collar PF07484.7 EXF82030.1 - 1.7e-11 43.7 0.2 5.6e-11 42.0 0.0 1.8 2 0 0 2 2 2 1 Phage Tail Collar Domain MFS_1 PF07690.11 EXF82032.1 - 3.5e-41 141.0 53.2 3.5e-40 137.8 35.6 2.4 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EXF82032.1 - 2.4e-13 49.2 25.9 3.5e-13 48.6 18.0 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Abhydrolase_6 PF12697.2 EXF82034.1 - 1.1e-25 90.8 0.8 3e-25 89.4 0.6 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF82034.1 - 0.00014 21.6 0.0 0.00036 20.3 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF82034.1 - 0.00054 19.5 0.0 0.0014 18.2 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Gryzun PF07919.7 EXF82035.1 - 4.6e-95 319.0 0.0 5.7e-95 318.7 0.0 1.1 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 EXF82035.1 - 2.9e-81 272.6 5.6 2.3e-76 256.5 2.8 2.3 2 0 0 2 2 2 2 Foie gras liver health family 1 Gryzun-like PF12742.2 EXF82035.1 - 0.00017 21.3 0.0 0.00039 20.1 0.0 1.7 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking RXT2_N PF08595.6 EXF82036.1 - 2.3e-36 124.8 0.2 1.2e-35 122.5 0.0 2.3 2 0 0 2 2 2 1 RXT2-like, N-terminal PEMT PF04191.8 EXF82037.1 - 4.8e-33 113.4 3.2 7.9e-33 112.7 2.2 1.4 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF4522 PF15022.1 EXF82037.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) Nramp PF01566.13 EXF82038.1 - 3.6e-80 269.4 28.8 3.6e-80 269.4 19.9 1.7 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein PTPA PF03095.10 EXF82040.1 - 3.4e-103 344.9 0.0 4.1e-103 344.6 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein Cutinase PF01083.17 EXF82041.1 - 1.6e-45 155.0 1.7 1.9e-45 154.7 1.2 1.0 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EXF82041.1 - 3.4e-05 23.3 0.0 5.2e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 EXF82041.1 - 0.042 13.6 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Abhydrolase_2 PF02230.11 EXF82041.1 - 0.043 13.2 0.0 0.15 11.4 0.0 1.8 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase p450 PF00067.17 EXF82044.1 - 6.3e-61 206.3 0.0 8e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_4 PF01565.18 EXF82045.1 - 3.6e-14 52.4 0.5 4e-10 39.2 0.1 2.4 1 1 1 2 2 2 2 FAD binding domain SCP2_2 PF13530.1 EXF82045.1 - 0.0021 17.4 0.0 0.0037 16.6 0.0 1.3 1 0 0 1 1 1 1 Sterol carrier protein domain Filament PF00038.16 EXF82046.1 - 9.7e-08 31.8 177.2 0.0047 16.4 27.8 6.7 1 1 4 5 5 5 5 Intermediate filament protein Reo_sigmaC PF04582.7 EXF82046.1 - 0.002 17.3 100.7 0.034 13.3 4.6 8.5 1 1 2 8 8 8 7 Reovirus sigma C capsid protein DUF4098 PF13345.1 EXF82046.1 - 0.0023 17.8 0.1 0.028 14.3 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4098) DUF3584 PF12128.3 EXF82046.1 - 5.5 4.1 213.4 0.013 12.8 21.6 6.2 1 1 6 7 7 7 0 Protein of unknown function (DUF3584) Patched PF02460.13 EXF82047.1 - 3e-75 253.7 15.9 4e-48 163.9 0.5 2.7 3 0 0 3 3 3 2 Patched family Sterol-sensing PF12349.3 EXF82047.1 - 3.9e-51 172.5 6.5 3.9e-51 172.5 4.5 2.9 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation Folate_rec PF03024.9 EXF82047.1 - 2.4e-05 24.0 1.5 5e-05 22.9 1.0 1.4 1 0 0 1 1 1 1 Folate receptor family MMPL PF03176.10 EXF82047.1 - 8.3e-05 21.4 34.0 0.00056 18.7 6.9 3.0 3 0 0 3 3 3 2 MMPL family HEAT_2 PF13646.1 EXF82047.1 - 0.089 13.0 0.1 2.2 8.5 0.0 2.7 3 0 0 3 3 3 0 HEAT repeats ACR_tran PF00873.14 EXF82047.1 - 8.2 3.6 24.0 0.085 10.2 9.7 2.1 2 0 0 2 2 2 0 AcrB/AcrD/AcrF family UvrD_C PF13361.1 EXF82049.1 - 2.6e-81 273.7 0.0 3.6e-81 273.3 0.0 1.2 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.16 EXF82049.1 - 3.5e-63 213.7 0.2 1.8e-60 204.8 0.0 3.0 2 1 0 2 2 2 1 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.1 EXF82049.1 - 4.1e-14 52.5 0.0 1.1e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EXF82049.1 - 4.5e-09 35.9 0.3 4.5e-09 35.9 0.2 2.3 3 0 0 3 3 3 1 Part of AAA domain AAA_12 PF13087.1 EXF82049.1 - 3.3e-05 23.3 0.0 0.00083 18.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.13 EXF82049.1 - 3.8e-05 23.3 0.1 0.98 8.8 0.0 3.3 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EXF82049.1 - 7.9e-05 22.3 0.2 0.056 13.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain CcmD PF04995.9 EXF82050.1 - 0.022 14.4 0.9 0.041 13.6 0.6 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF2017 PF09438.5 EXF82051.1 - 0.16 11.5 0.7 0.44 10.0 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2017) DUF2014 PF09427.5 EXF82052.1 - 9.8e-105 349.3 6.4 1.5e-104 348.8 4.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF2014) HLH PF00010.21 EXF82052.1 - 5.3e-17 61.2 0.8 5.3e-17 61.2 0.5 2.5 3 0 0 3 3 3 1 Helix-loop-helix DNA-binding domain CCDC155 PF14662.1 EXF82052.1 - 0.025 14.2 0.7 0.025 14.2 0.5 2.3 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 Ceramidase_alk PF04734.8 EXF82053.1 - 9.9e-259 859.7 0.0 1.3e-258 859.3 0.0 1.1 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase HET PF06985.6 EXF82053.1 - 8.3e-23 81.0 0.1 1.7e-22 80.0 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) G_glu_transpept PF01019.16 EXF82055.1 - 5.8e-162 539.7 0.1 6.8e-162 539.5 0.1 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase Methyltransf_2 PF00891.13 EXF82056.1 - 2.4e-20 72.7 0.0 4.8e-20 71.7 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_PK PF05891.7 EXF82056.1 - 6.9e-06 25.5 0.0 1.2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase FeoC PF09012.5 EXF82056.1 - 0.014 15.0 0.0 0.032 13.9 0.0 1.6 1 0 0 1 1 1 0 FeoC like transcriptional regulator MTS PF05175.9 EXF82056.1 - 0.069 12.5 1.1 1.1 8.5 0.4 2.7 2 2 1 3 3 3 0 Methyltransferase small domain DREV PF05219.7 EXF82056.1 - 0.096 11.5 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_32 PF13679.1 EXF82056.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EXF82056.1 - 0.14 12.7 0.0 0.38 11.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain adh_short PF00106.20 EXF82057.1 - 1.2e-32 113.0 1.3 1.9e-32 112.4 0.9 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF82057.1 - 1.4e-30 106.8 0.0 1.8e-30 106.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF82057.1 - 5.4e-14 52.2 0.1 8.1e-14 51.6 0.1 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EXF82057.1 - 0.005 16.8 0.9 0.0086 16.0 0.6 1.7 1 1 0 1 1 1 1 NADH(P)-binding Pyr_redox PF00070.22 EXF82057.1 - 0.009 16.3 0.1 0.017 15.4 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase THF_DHG_CYH_C PF02882.14 EXF82057.1 - 0.018 14.1 0.2 0.11 11.5 0.0 2.0 1 1 1 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EXF82057.1 - 0.032 14.0 0.1 0.032 14.0 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EXF82057.1 - 0.032 13.6 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family MBOAT_2 PF13813.1 EXF82058.1 - 1.7e-10 40.8 1.5 1.7e-10 40.8 1.0 3.0 4 0 0 4 4 4 1 Membrane bound O-acyl transferase family FAD_binding_4 PF01565.18 EXF82059.1 - 1.6e-16 60.0 1.8 3.1e-16 59.1 1.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF82059.1 - 2.6e-08 33.6 0.1 5.8e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Tyrosinase PF00264.15 EXF82062.1 - 2.1e-36 126.1 0.0 3.7e-36 125.3 0.0 1.4 2 0 0 2 2 2 1 Common central domain of tyrosinase LEA_6 PF10714.4 EXF82063.1 - 0.78 9.5 2.9 1.5 8.6 2.0 1.4 1 0 0 1 1 1 0 Late embryogenesis abundant protein 18 DAO PF01266.19 EXF82064.1 - 3e-09 36.2 0.0 5.2e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF82064.1 - 1.6e-06 27.2 1.3 8.3e-06 24.9 1.2 1.8 2 0 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.14 EXF82064.1 - 6.2e-06 25.5 4.9 0.03 13.4 0.2 2.7 2 1 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 EXF82064.1 - 6.6e-06 24.8 0.2 0.0013 17.2 0.3 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 EXF82064.1 - 1e-05 25.4 0.0 2.6e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF82064.1 - 0.00036 20.4 0.3 0.00065 19.6 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EXF82064.1 - 0.004 16.2 0.4 0.0066 15.5 0.3 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EXF82064.1 - 0.0044 15.9 0.3 0.0066 15.3 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EXF82064.1 - 0.014 14.9 0.0 0.06 12.9 0.0 2.0 3 0 0 3 3 3 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.22 EXF82064.1 - 0.016 15.5 0.4 0.15 12.4 0.7 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF82064.1 - 0.032 13.3 0.1 0.06 12.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family 3HCDH_N PF02737.13 EXF82064.1 - 0.04 13.5 0.1 0.067 12.8 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.1 EXF82064.1 - 0.093 12.7 0.1 0.29 11.1 0.1 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans_2 PF11951.3 EXF82065.1 - 2.2e-12 46.2 0.6 2.3e-11 42.9 0.4 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 EXF82066.1 - 1.8e-16 60.7 0.3 2.4e-16 60.3 0.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF82066.1 - 1.8e-14 53.7 0.0 2.9e-14 53.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EXF82066.1 - 3.9e-09 36.1 0.0 1.1e-08 34.6 0.0 1.7 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.13 EXF82066.1 - 6.9e-06 25.6 0.5 1.8e-05 24.3 0.3 1.8 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 EXF82066.1 - 4.9e-05 23.1 0.0 0.0001 22.0 0.0 1.6 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal AXE1 PF05448.7 EXF82066.1 - 0.00012 20.7 0.6 0.00019 20.0 0.2 1.4 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.15 EXF82066.1 - 0.00017 21.2 0.7 0.00036 20.1 0.5 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EXF82066.1 - 0.00054 19.7 0.3 0.0014 18.4 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EXF82066.1 - 0.0017 17.5 0.2 0.0047 16.1 0.1 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family adh_short PF00106.20 EXF82067.1 - 4.5e-18 65.7 0.1 6.5e-18 65.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF82067.1 - 2e-06 27.5 0.0 3.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF82067.1 - 9.5e-06 25.5 0.0 1.3e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EXF82067.1 - 8.2e-05 22.1 0.0 0.00011 21.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF82067.1 - 0.00014 21.8 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EXF82067.1 - 0.00018 20.8 0.0 0.00026 20.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family DUF1776 PF08643.5 EXF82067.1 - 0.00037 19.7 0.0 0.00048 19.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) ADH_zinc_N PF00107.21 EXF82067.1 - 0.031 13.8 0.3 0.27 10.7 0.1 2.4 3 0 0 3 3 3 0 Zinc-binding dehydrogenase Flavoprotein PF02441.14 EXF82070.1 - 2.1e-16 59.7 0.0 4e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Flavoprotein Ank_4 PF13637.1 EXF82070.1 - 0.024 15.1 0.0 0.22 12.0 0.0 2.7 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Flavodoxin_2 PF02525.12 EXF82070.1 - 0.1 12.1 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Flavodoxin-like fold Ank_2 PF12796.2 EXF82073.1 - 2.3e-22 79.1 0.0 3.9e-07 30.3 0.0 4.6 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EXF82073.1 - 4e-19 67.3 6.1 8.8e-05 22.1 0.1 6.7 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.1 EXF82073.1 - 8e-19 67.2 0.7 2e-09 37.4 0.1 3.9 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EXF82073.1 - 1.9e-18 66.4 0.2 0.0027 18.1 0.0 6.8 5 2 1 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF82073.1 - 1.5e-12 46.4 0.1 0.08 13.2 0.0 6.3 6 0 0 6 6 6 3 Ankyrin repeat NACHT PF05729.7 EXF82073.1 - 0.092 12.3 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 EXF82074.1 - 0.0011 18.6 0.0 0.0027 17.4 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 EXF82074.1 - 0.0043 16.7 0.0 0.03 13.9 0.0 2.1 2 0 0 2 2 2 1 NACHT domain UPF0079 PF02367.12 EXF82074.1 - 0.094 12.3 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 MFS_1 PF07690.11 EXF82075.1 - 3.6e-31 108.1 35.3 3.6e-31 108.1 24.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF82075.1 - 0.00012 20.8 19.9 0.00012 20.8 13.8 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter Fungal_trans PF04082.13 EXF82076.1 - 2.2e-28 98.8 0.4 5.3e-28 97.6 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain SNF PF00209.13 EXF82078.1 - 1.9e-89 300.5 31.5 1.3e-88 297.7 21.8 1.9 1 1 0 1 1 1 1 Sodium:neurotransmitter symporter family DUF4241 PF14025.1 EXF82078.1 - 0.25 11.0 1.1 0.41 10.4 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4241) Aldo_ket_red PF00248.16 EXF82079.1 - 5.5e-50 169.7 0.0 6.3e-50 169.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HAD_2 PF13419.1 EXF82079.1 - 0.0063 16.7 0.0 0.25 11.5 0.0 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Fungal_trans_2 PF11951.3 EXF82080.1 - 0.012 14.2 0.2 0.019 13.5 0.1 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain OPT PF03169.10 EXF82081.1 - 1.4e-162 542.3 57.4 1.6e-162 542.1 39.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein E1-E2_ATPase PF00122.15 EXF82081.1 - 0.27 10.2 0.5 0.55 9.2 0.4 1.5 1 0 0 1 1 1 0 E1-E2 ATPase ADH_zinc_N PF00107.21 EXF82082.1 - 2.7e-17 62.5 0.0 4.8e-17 61.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF82082.1 - 4.8e-07 29.5 0.4 1.6e-06 27.8 0.2 1.9 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EXF82082.1 - 1.1e-06 29.5 0.0 2e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GxGYxYP PF14323.1 EXF82083.1 - 9.7e-91 304.7 0.0 7.1e-63 212.9 0.0 2.1 2 0 0 2 2 2 2 GxGYxY sequence motif in domain of unknown function PHO4 PF01384.15 EXF82084.1 - 8.5e-111 369.7 18.0 1e-110 369.4 12.5 1.0 1 0 0 1 1 1 1 Phosphate transporter family NAD_binding_10 PF13460.1 EXF82085.1 - 5.4e-16 59.1 0.0 8.4e-16 58.4 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EXF82085.1 - 2e-14 53.4 0.0 2.8e-14 52.9 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 EXF82085.1 - 2.7e-05 23.3 0.0 3.7e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 EXF82085.1 - 0.0004 20.2 0.0 0.00069 19.5 0.0 1.3 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.17 EXF82085.1 - 0.00047 20.6 0.1 0.00085 19.8 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EXF82085.1 - 0.0019 18.4 0.0 0.0067 16.7 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain DUF3798 PF12683.2 EXF82085.1 - 0.0037 16.4 0.0 0.0072 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3798) Epimerase PF01370.16 EXF82085.1 - 0.02 14.3 0.0 0.04 13.3 0.0 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EXF82085.1 - 0.028 13.3 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein RmlD_sub_bind PF04321.12 EXF82085.1 - 0.032 13.1 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain DFP PF04127.10 EXF82085.1 - 0.06 12.9 0.1 2.8 7.5 0.0 2.1 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein Sugar_tr PF00083.19 EXF82086.1 - 1.1e-95 320.8 20.8 1.3e-95 320.6 14.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF82086.1 - 2.2e-30 105.5 58.9 1.1e-25 90.0 18.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily LacY_symp PF01306.14 EXF82086.1 - 0.0031 16.1 0.1 0.0031 16.1 0.1 3.3 4 0 0 4 4 4 1 LacY proton/sugar symporter Herpes_LMP1 PF05297.6 EXF82086.1 - 0.053 12.4 12.8 0.0071 15.3 2.6 2.2 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) MFS_1 PF07690.11 EXF82087.1 - 6.7e-14 51.3 31.4 5.4e-13 48.3 18.4 3.4 1 1 1 2 2 2 2 Major Facilitator Superfamily YcxB PF14317.1 EXF82087.1 - 0.042 13.0 0.3 0.11 11.7 0.2 1.6 1 0 0 1 1 1 0 YcxB-like protein DUF4231 PF14015.1 EXF82087.1 - 0.72 9.8 0.0 0.72 9.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) 60KD_IMP PF02096.15 EXF82087.1 - 0.92 9.1 7.0 3 7.4 3.8 2.4 2 1 0 2 2 2 0 60Kd inner membrane protein VIT1 PF01988.14 EXF82087.1 - 1.1 8.6 4.6 0.36 10.2 0.2 2.1 1 1 1 2 2 2 0 VIT family p450 PF00067.17 EXF82088.1 - 7.3e-52 176.4 0.0 1.9e-31 109.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF2235 PF09994.4 EXF82089.1 - 8.7e-64 215.5 0.7 4.6e-62 209.8 0.5 2.4 1 1 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Ribonuclease PF00545.15 EXF82090.1 - 5.6e-17 61.5 0.5 1e-07 31.9 0.0 2.5 2 1 1 3 3 3 2 ribonuclease NmrA PF05368.8 EXF82091.1 - 7.7e-32 110.4 0.0 2.1e-30 105.7 0.0 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF82091.1 - 0.00042 20.3 0.1 0.00062 19.8 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 EXF82091.1 - 0.033 14.0 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Hira PF07569.6 EXF82092.1 - 4.1e-84 281.1 0.0 1.2e-83 279.6 0.0 1.8 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.27 EXF82092.1 - 5.7e-42 140.1 20.1 3.2e-07 29.9 0.1 8.6 8 0 0 8 8 8 6 WD domain, G-beta repeat HIRA_B PF09453.5 EXF82092.1 - 3.7e-08 32.6 0.4 9e-08 31.4 0.3 1.7 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 EXF82092.1 - 0.00046 19.7 0.4 8 6.2 0.0 4.4 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EXF82092.1 - 0.013 13.3 0.2 0.076 10.8 0.0 2.1 3 0 0 3 3 3 0 IKI3 family YmzC PF14157.1 EXF82092.1 - 0.21 11.4 0.0 0.47 10.3 0.0 1.5 1 0 0 1 1 1 0 YmzC-like protein ATP-grasp_3 PF02655.9 EXF82093.1 - 0.0045 16.8 0.0 0.013 15.3 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EXF82093.1 - 0.057 13.1 0.0 0.13 12.0 0.0 1.6 1 1 0 1 1 1 0 ATP-grasp domain ATP-grasp PF02222.17 EXF82093.1 - 0.11 11.8 0.0 0.36 10.1 0.0 1.9 1 1 0 1 1 1 0 ATP-grasp domain WEMBL PF05701.6 EXF82096.1 - 0.021 13.3 84.9 0.0046 15.4 31.8 3.1 1 1 2 3 3 3 0 Weak chloroplast movement under blue light Reo_sigmaC PF04582.7 EXF82096.1 - 0.22 10.6 17.1 0.25 10.5 0.4 4.4 2 2 1 5 5 5 0 Reovirus sigma C capsid protein Filament PF00038.16 EXF82096.1 - 2 7.7 85.8 1.8 7.9 5.0 5.2 1 1 3 4 4 4 0 Intermediate filament protein DUF1664 PF07889.7 EXF82096.1 - 3 7.6 34.1 0.047 13.4 1.1 6.1 2 1 4 6 6 6 0 Protein of unknown function (DUF1664) DUF2422 PF10337.4 EXF82097.1 - 3.3e-92 309.6 0.0 3.3e-92 309.6 0.0 3.1 2 2 0 2 2 2 1 Protein of unknown function (DUF2422) FUSC_2 PF13515.1 EXF82097.1 - 3.7e-15 55.9 19.2 3.7e-15 55.9 13.3 2.8 2 1 0 2 2 2 1 Fusaric acid resistance protein-like DUF2421 PF10334.4 EXF82097.1 - 1.4e-06 28.0 1.3 6.5e-06 25.9 0.2 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF2421) ALMT PF11744.3 EXF82097.1 - 0.37 9.4 15.0 1.2 7.7 8.7 2.5 2 1 0 2 2 2 0 Aluminium activated malate transporter HET PF06985.6 EXF82098.1 - 7.2e-17 61.8 1.7 1.1e-13 51.5 0.0 2.3 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Velvet PF11754.3 EXF82099.1 - 2.3e-43 148.1 0.8 1.2e-42 145.8 0.6 2.1 1 1 0 1 1 1 1 Velvet factor Phage_X PF05155.10 EXF82099.1 - 0.049 13.5 0.4 0.11 12.4 0.3 1.5 1 0 0 1 1 1 0 Phage X family BBE PF08031.7 EXF82100.1 - 1.6e-09 37.5 0.0 3.4e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like FAD_binding_4 PF01565.18 EXF82100.1 - 3.5e-09 36.2 0.1 7.4e-09 35.2 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain SnoaL_3 PF13474.1 EXF82101.1 - 2.7e-08 33.8 0.2 4.1e-08 33.2 0.1 1.5 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EXF82101.1 - 0.003 17.7 1.1 0.0054 16.9 0.5 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4440) Pyr_redox_3 PF13738.1 EXF82102.1 - 2.9e-25 89.5 0.0 5.1e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF82102.1 - 1.2e-14 54.6 0.0 1.3e-08 34.9 0.0 2.9 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EXF82102.1 - 1.3e-13 50.0 0.0 2.6e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like K_oxygenase PF13434.1 EXF82102.1 - 2e-13 49.9 0.0 7.5e-12 44.8 0.0 2.2 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EXF82102.1 - 8.8e-09 35.3 0.1 6.4e-05 22.7 0.0 3.9 3 1 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EXF82102.1 - 1.6e-08 34.4 0.0 1.2e-07 31.6 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF82102.1 - 1.1e-07 31.0 0.5 0.001 18.0 0.3 3.3 3 0 0 3 3 3 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF82102.1 - 0.00015 20.8 0.0 0.00046 19.2 0.0 1.8 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 EXF82102.1 - 0.00074 19.7 0.0 0.23 11.7 0.0 2.8 2 1 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.12 EXF82102.1 - 0.00081 18.5 0.0 0.094 11.7 0.0 2.4 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 EXF82102.1 - 0.0012 17.7 0.2 0.49 9.2 0.1 2.5 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EXF82102.1 - 0.019 13.8 0.0 0.037 12.8 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain FAD_oxidored PF12831.2 EXF82102.1 - 0.026 13.5 0.5 0.35 9.9 0.4 2.2 1 1 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EXF82102.1 - 0.032 13.3 0.0 0.15 11.0 0.0 2.1 3 0 0 3 3 3 0 FAD binding domain HI0933_like PF03486.9 EXF82102.1 - 0.051 12.0 0.1 0.12 10.8 0.1 1.6 1 0 0 1 1 1 0 HI0933-like protein Shikimate_DH PF01488.15 EXF82102.1 - 0.056 13.5 0.0 6.8 6.8 0.0 2.5 3 0 0 3 3 2 0 Shikimate / quinate 5-dehydrogenase Pyr_redox PF00070.22 EXF82102.1 - 0.069 13.5 0.0 8.9 6.8 0.1 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EXF82102.1 - 0.3 10.9 0.8 1.1 9.1 0.1 2.1 2 0 0 2 2 2 0 ThiF family p450 PF00067.17 EXF82103.1 - 6.8e-72 242.4 0.0 8.1e-72 242.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_S8 PF00082.17 EXF82105.1 - 1e-43 149.5 0.4 3.8e-43 147.6 0.3 1.9 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EXF82105.1 - 2.3e-08 34.4 2.2 2.3e-08 34.4 1.5 1.9 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) FlgD_ig PF13860.1 EXF82105.1 - 4.9e-06 26.1 0.8 4.3e-05 23.1 0.0 2.5 2 0 0 2 2 2 1 FlgD Ig-like domain adh_short PF00106.20 EXF82106.1 - 3.1e-11 43.4 0.1 2.4e-05 24.2 0.0 3.0 3 0 0 3 3 3 2 short chain dehydrogenase adh_short_C2 PF13561.1 EXF82106.1 - 9.5e-07 28.8 0.0 0.0087 15.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase zf-C3HC PF07967.8 EXF82106.1 - 0.18 11.5 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 C3HC zinc finger-like Zn_clus PF00172.13 EXF82107.1 - 9.5e-06 25.4 8.7 1.9e-05 24.4 6.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF82107.1 - 1.2e-05 24.3 0.3 2.2e-05 23.4 0.2 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain MFS_1 PF07690.11 EXF82108.1 - 5.9e-34 117.3 70.7 6.4e-26 90.8 27.0 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF82108.1 - 6.5e-13 48.0 33.7 3.3e-08 32.5 9.1 3.0 2 1 1 3 3 3 2 Sugar (and other) transporter MFS_2 PF13347.1 EXF82108.1 - 1.5e-06 26.9 9.1 1.5e-06 26.9 6.3 2.4 1 1 1 2 2 2 1 MFS/sugar transport protein DUF1996 PF09362.5 EXF82109.1 - 4.1e-52 177.1 0.2 5.2e-52 176.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) Lipase_GDSL_2 PF13472.1 EXF82110.1 - 1e-15 58.3 0.2 2.3e-15 57.1 0.2 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EXF82110.1 - 4.8e-08 33.1 0.3 1.3e-07 31.7 0.1 1.9 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase PSII_BNR PF14870.1 EXF82110.1 - 6.2e-08 31.9 6.5 3.9e-05 22.8 0.1 3.4 3 1 1 4 4 4 2 Photosynthesis system II assembly factor YCF48 BNR PF02012.15 EXF82110.1 - 1.1e-07 30.5 22.5 0.5 10.3 0.4 6.4 5 0 0 5 5 5 5 BNR/Asp-box repeat BNR_2 PF13088.1 EXF82110.1 - 0.00041 19.7 1.1 2.4 7.3 0.0 3.6 3 1 0 3 3 3 2 BNR repeat-like domain Mo-co_dimer PF03404.11 EXF82110.1 - 0.49 10.0 4.8 21 4.7 0.0 4.4 5 0 0 5 5 5 0 Mo-co oxidoreductase dimerisation domain p450 PF00067.17 EXF82111.1 - 7.4e-25 87.3 0.0 9.4e-25 87.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Arrestin_N PF00339.24 EXF82112.1 - 3e-07 30.3 0.0 1.1e-06 28.5 0.0 1.9 1 1 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EXF82112.1 - 0.00026 21.1 1.2 0.28 11.3 0.0 2.6 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Bul1_C PF04426.7 EXF82112.1 - 0.0048 16.1 0.1 0.0095 15.1 0.0 1.4 1 0 0 1 1 1 1 Bul1 C terminus Bul1_N PF04425.7 EXF82112.1 - 0.0068 15.0 0.3 0.018 13.6 0.0 1.7 2 0 0 2 2 2 1 Bul1 N terminus ECH PF00378.15 EXF82113.1 - 8.3e-39 133.1 0.6 8.1e-38 129.9 0.4 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EXF82113.1 - 0.021 14.5 0.1 2 8.2 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 NAD_binding_2 PF03446.10 EXF82114.1 - 1.9e-31 109.1 0.1 4e-31 108.0 0.0 1.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EXF82114.1 - 1.3e-16 60.7 0.3 2.4e-16 59.9 0.2 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EXF82114.1 - 0.0027 18.1 0.0 0.0057 17.0 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent UDPG_MGDP_dh_N PF03721.9 EXF82114.1 - 0.06 12.7 0.0 0.29 10.4 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Homeobox_KN PF05920.6 EXF82115.1 - 1.3e-12 47.2 2.4 4.6e-12 45.4 1.7 2.1 1 0 0 1 1 1 1 Homeobox KN domain zf-C2H2_4 PF13894.1 EXF82115.1 - 3.9e-05 23.6 22.9 0.025 14.8 3.2 5.0 4 0 0 4 4 4 3 C2H2-type zinc finger Homeobox PF00046.24 EXF82115.1 - 5.7e-05 22.6 1.3 0.00017 21.1 0.9 1.8 1 0 0 1 1 1 1 Homeobox domain zf-C2H2 PF00096.21 EXF82115.1 - 0.0006 19.9 24.0 0.0047 17.1 2.9 4.6 4 0 0 4 4 4 2 Zinc finger, C2H2 type HTH_Tnp_Tc5 PF03221.11 EXF82115.1 - 0.0016 18.2 2.2 0.75 9.6 0.1 3.1 2 1 0 2 2 2 2 Tc5 transposase DNA-binding domain A2L_zn_ribbon PF08792.5 EXF82115.1 - 1.1 8.8 5.4 2.3 7.7 0.2 3.2 3 0 0 3 3 3 0 A2L zinc ribbon domain zf-C2H2_2 PF12756.2 EXF82115.1 - 2.5 8.2 10.9 14 5.8 0.3 3.5 2 1 0 3 3 3 0 C2H2 type zinc-finger (2 copies) MFS_1 PF07690.11 EXF82116.1 - 1.6e-24 86.2 38.3 1.6e-24 86.2 26.6 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1 PF07690.11 EXF82117.1 - 5.1e-35 120.8 30.2 5.1e-35 120.8 20.9 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily GFA PF04828.9 EXF82118.1 - 2.2e-14 53.1 1.5 4e-06 26.6 0.0 3.4 3 0 0 3 3 3 3 Glutathione-dependent formaldehyde-activating enzyme NOB1_Zn_bind PF08772.6 EXF82118.1 - 0.0036 17.1 1.1 0.95 9.3 0.1 2.7 2 0 0 2 2 2 2 Nin one binding (NOB1) Zn-ribbon like peroxidase PF00141.18 EXF82119.1 - 9.2e-84 280.4 0.2 2e-46 158.3 0.0 2.2 2 0 0 2 2 2 2 Peroxidase MFS_1 PF07690.11 EXF82120.1 - 1.7e-47 161.8 57.1 2.7e-47 161.2 38.4 2.3 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EXF82120.1 - 1.8e-18 66.1 19.1 5.1e-18 64.6 13.2 1.7 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EXF82120.1 - 5.5e-14 51.5 7.5 5.5e-14 51.5 5.2 3.4 2 1 1 3 3 3 1 Sugar (and other) transporter adh_short PF00106.20 EXF82121.1 - 1.3e-21 77.2 0.1 2.2e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF82121.1 - 7.3e-11 42.0 0.0 1.4e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF82121.1 - 5.9e-07 29.1 0.0 8.3e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EXF82121.1 - 0.0016 18.5 0.0 0.0035 17.4 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Saccharop_dh PF03435.13 EXF82121.1 - 0.0022 17.0 0.0 0.003 16.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EXF82121.1 - 0.0041 17.1 0.1 0.01 15.8 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EXF82121.1 - 0.0044 15.9 0.0 0.0056 15.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 EXF82121.1 - 0.012 15.8 0.1 0.034 14.4 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF3425 PF11905.3 EXF82122.1 - 3.2e-32 111.2 0.0 4.8e-32 110.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) Acetyltransf_1 PF00583.19 EXF82123.1 - 3.4e-15 55.8 0.0 5.5e-15 55.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF82123.1 - 7.4e-10 38.8 0.0 1.1e-09 38.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EXF82123.1 - 2.2e-08 34.3 0.0 2.9e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EXF82123.1 - 4e-07 30.1 0.0 5.5e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EXF82123.1 - 0.00028 20.7 0.0 0.00043 20.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EXF82123.1 - 0.00032 20.6 0.0 0.00037 20.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EXF82123.1 - 0.0095 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EXF82123.1 - 0.016 14.9 0.1 0.054 13.2 0.0 1.9 1 1 1 2 2 2 0 FR47-like protein Ank_2 PF12796.2 EXF82126.1 - 2.2e-24 85.6 0.0 7.1e-12 45.5 0.0 4.5 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EXF82126.1 - 1.2e-20 73.4 2.3 2.6e-06 27.7 0.0 5.7 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF82126.1 - 1.2e-16 59.0 5.5 0.13 12.5 0.0 8.2 9 1 1 10 10 10 6 Ankyrin repeat Ank PF00023.25 EXF82126.1 - 1.5e-14 52.9 3.8 0.0041 16.8 0.0 7.1 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 EXF82126.1 - 1.8e-12 47.0 2.4 0.043 14.0 0.2 6.7 3 3 4 7 7 7 4 Ankyrin repeats (many copies) F-box PF00646.28 EXF82126.1 - 2.8e-05 23.6 0.2 7.4e-05 22.2 0.1 1.7 1 0 0 1 1 1 1 F-box domain Glyco_transf_15 PF01793.11 EXF82127.1 - 3.3e-69 233.3 0.7 5e-68 229.4 0.5 2.3 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase DUF1348 PF07080.6 EXF82128.1 - 0.065 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1348) Acetyltransf_1 PF00583.19 EXF82130.1 - 1.6e-07 31.2 0.0 2.2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF82130.1 - 6.4e-05 23.0 0.0 0.0001 22.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EXF82130.1 - 0.0031 17.2 0.0 0.005 16.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EXF82130.1 - 0.0037 17.3 0.0 0.005 16.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EXF82130.1 - 0.092 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FtsJ PF01728.14 EXF82131.1 - 1.5e-59 201.0 0.0 1.9e-59 200.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase NSP13 PF06460.7 EXF82131.1 - 0.055 12.3 0.0 0.092 11.5 0.0 1.3 1 0 0 1 1 1 0 Coronavirus NSP13 DEAD PF00270.24 EXF82132.1 - 4.3e-43 146.7 0.0 1.2e-41 142.0 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF82132.1 - 1.5e-20 72.8 0.0 3.4e-20 71.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EXF82132.1 - 1.2e-05 24.3 0.0 1.9e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1910 PF08928.5 EXF82133.1 - 0.016 15.2 0.4 0.016 15.2 0.3 5.9 6 0 0 6 6 6 0 Domain of unknown function (DUF1910) CRCB PF02537.10 EXF82134.1 - 0.46 10.3 8.1 0.065 13.1 2.9 1.7 2 0 0 2 2 2 0 CrcB-like protein COesterase PF00135.23 EXF82135.1 - 1.2e-95 321.2 0.0 1.5e-95 320.9 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF82135.1 - 0.0095 15.5 0.5 0.087 12.3 0.4 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EXF82135.1 - 0.056 12.6 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family TRAUB PF08164.7 EXF82136.1 - 0.093 12.8 0.1 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 Apoptosis-antagonizing transcription factor, C-terminal Syndecan PF01034.15 EXF82137.1 - 9.1e-06 25.2 0.1 1.8e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Syndecan domain TrbL PF04610.9 EXF82137.1 - 0.078 12.6 2.3 0.16 11.6 1.6 1.5 1 0 0 1 1 1 0 TrbL/VirB6 plasmid conjugal transfer protein Rifin_STEVOR PF02009.11 EXF82137.1 - 0.49 9.9 6.1 0.098 12.2 0.2 2.1 2 0 0 2 2 2 0 Rifin/stevor family TPR_MLP1_2 PF07926.7 EXF82138.1 - 3.7e-31 107.5 28.5 3.7e-31 107.5 19.7 16.7 6 4 8 14 14 14 4 TPR/MLP1/MLP2-like protein DUF904 PF06005.7 EXF82138.1 - 0.00034 20.8 4.6 0.00034 20.8 3.2 24.7 15 8 4 19 19 19 1 Protein of unknown function (DUF904) Rootletin PF15035.1 EXF82138.1 - 0.00071 19.6 9.8 0.00071 19.6 6.8 16.8 4 2 11 16 16 16 2 Ciliary rootlet component, centrosome cohesion Tropomyosin_1 PF12718.2 EXF82138.1 - 0.0022 17.8 7.5 0.0022 17.8 5.2 17.3 6 5 10 16 16 16 2 Tropomyosin like CENP-Q PF13094.1 EXF82138.1 - 0.0049 16.9 15.2 0.0049 16.9 10.5 16.9 6 4 10 17 17 17 3 CENP-Q, a CENPA-CAD centromere complex subunit Mnd1 PF03962.10 EXF82138.1 - 0.0051 16.5 9.2 0.0051 16.5 6.4 17.9 7 2 8 16 16 16 3 Mnd1 family p450 PF00067.17 EXF82139.1 - 9.3e-42 143.1 0.0 1.2e-41 142.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EXF82140.1 - 1.5e-14 54.2 0.0 1.9e-13 50.6 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF82140.1 - 0.0015 18.2 0.0 0.0027 17.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Spore_GerAC PF05504.6 EXF82140.1 - 0.18 11.5 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal FAD_binding_4 PF01565.18 EXF82142.1 - 3.4e-18 65.4 2.7 6.7e-18 64.4 1.3 1.9 2 0 0 2 2 2 1 FAD binding domain MFS_1 PF07690.11 EXF82143.1 - 6.1e-36 123.8 16.6 6.1e-36 123.8 11.5 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Neurensin PF14927.1 EXF82143.1 - 0.21 10.9 1.7 0.29 10.5 0.1 2.1 2 0 0 2 2 2 0 Neurensin Cu-oxidase_3 PF07732.10 EXF82144.1 - 4.7e-38 129.5 2.7 4.7e-38 129.5 1.9 3.0 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EXF82144.1 - 5.8e-37 126.2 5.1 5.8e-37 126.2 3.5 2.5 3 1 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EXF82144.1 - 2.4e-35 121.7 0.5 2.3e-34 118.6 0.1 2.4 2 0 0 2 2 2 1 Multicopper oxidase E1-E2_ATPase PF00122.15 EXF82146.1 - 1.9e-57 193.9 0.6 4.9e-57 192.6 0.4 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EXF82146.1 - 6.5e-45 152.8 6.0 6.5e-45 152.8 4.1 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EXF82146.1 - 1.2e-29 104.2 0.2 5e-29 102.2 0.1 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EXF82146.1 - 3.6e-19 68.4 0.0 7.1e-19 67.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EXF82146.1 - 4.4e-13 49.8 0.0 5.4e-12 46.2 0.0 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EXF82146.1 - 8e-11 41.2 0.0 2.1e-09 36.6 0.0 2.9 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EXF82146.1 - 8.1e-05 22.3 0.3 0.00036 20.1 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase DUF3325 PF11804.3 EXF82146.1 - 0.047 13.6 9.8 2 8.4 0.0 4.3 4 1 1 5 5 5 0 Protein of unknown function (DUF3325) HET PF06985.6 EXF82148.1 - 3.6e-22 79.0 0.0 6e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AA_permease PF00324.16 EXF82149.1 - 3.8e-100 335.4 37.0 4.7e-100 335.1 25.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF82149.1 - 1.7e-30 105.9 42.1 2.1e-30 105.6 29.2 1.0 1 0 0 1 1 1 1 Amino acid permease DUF2665 PF11654.3 EXF82149.1 - 0.11 12.0 1.3 0.25 10.9 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2665) DUF1479 PF07350.7 EXF82150.1 - 6e-150 499.3 0.0 7.3e-150 499.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) MFS_1 PF07690.11 EXF82151.1 - 5.7e-17 61.4 34.1 5.7e-17 61.4 23.7 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Lactamase_B_2 PF12706.2 EXF82152.1 - 6.8e-10 38.8 0.0 1.6e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DRMBL PF07522.9 EXF82152.1 - 2.3e-07 30.8 0.1 8.2e-07 29.0 0.0 1.9 2 0 0 2 2 2 1 DNA repair metallo-beta-lactamase Lactamase_B PF00753.22 EXF82152.1 - 2e-05 24.3 0.0 4.9e-05 23.0 0.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 EXF82152.1 - 0.0057 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase MFS_1 PF07690.11 EXF82153.1 - 3.9e-45 154.0 29.3 3.9e-45 154.0 20.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily V_ATPase_I PF01496.14 EXF82154.1 - 1.7 6.4 3.3 2.6 5.7 2.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NAM-associated PF14303.1 EXF82155.1 - 3.2 8.0 10.8 3.6 7.8 7.5 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain Pil1 PF13805.1 EXF82155.1 - 5.1 6.1 8.2 6.4 5.8 5.7 1.1 1 0 0 1 1 1 0 Eisosome component PIL1 CAP59_mtransfer PF11735.3 EXF82156.1 - 7.4e-59 198.9 0.0 1e-58 198.4 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 DnaB_C PF03796.10 EXF82157.1 - 0.052 12.4 1.2 0.064 12.1 0.1 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain LUC7 PF03194.10 EXF82157.1 - 0.17 11.3 2.9 0.29 10.6 2.0 1.3 1 0 0 1 1 1 0 LUC7 N_terminus CorA PF01544.13 EXF82157.1 - 0.26 10.3 8.4 0.82 8.6 5.8 1.9 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Glyco_transf_28 PF03033.15 EXF82159.1 - 7.7e-07 28.9 0.0 2e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EXF82159.1 - 1.7e-05 23.6 0.0 2.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase B12-binding PF02310.14 EXF82159.1 - 0.012 15.4 0.1 0.041 13.7 0.0 2.0 2 0 0 2 2 2 0 B12 binding domain Glyco_tran_28_C PF04101.11 EXF82159.1 - 0.027 14.1 0.0 0.061 12.9 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain p450 PF00067.17 EXF82160.1 - 2.5e-53 181.2 0.0 8e-40 136.7 0.0 2.1 1 1 1 2 2 2 2 Cytochrome P450 Cu-oxidase_3 PF07732.10 EXF82160.1 - 1.9e-31 108.2 0.6 9.1e-31 106.0 0.0 2.5 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase PF00394.17 EXF82160.1 - 5.8e-31 107.5 0.2 1.9e-30 105.8 0.1 1.9 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EXF82160.1 - 1.5e-20 73.1 10.1 3.8e-19 68.5 1.3 3.3 3 1 0 3 3 3 2 Multicopper oxidase MFS_1 PF07690.11 EXF82161.1 - 4.2e-32 111.2 29.2 4.3e-32 111.1 18.8 1.8 2 0 0 2 2 2 1 Major Facilitator Superfamily SPC12 PF06645.8 EXF82161.1 - 0.21 11.4 8.3 0.3 10.8 0.1 3.4 3 0 0 3 3 3 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Arylsulfotran_2 PF14269.1 EXF82162.1 - 2.9e-58 197.3 0.1 4.4e-58 196.7 0.0 1.2 1 0 0 1 1 1 1 Arylsulfotransferase (ASST) Arylsulfotrans PF05935.6 EXF82162.1 - 3.8e-22 78.4 0.1 1.3e-21 76.7 0.0 1.7 1 1 0 1 1 1 1 Arylsulfotransferase (ASST) DUF3437 PF11919.3 EXF82164.1 - 6.1e-32 109.1 0.0 1.8e-31 107.6 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3437) Adaptin_N PF01602.15 EXF82164.1 - 0.12 10.7 0.0 16 3.6 0.0 3.1 2 1 0 3 3 3 0 Adaptin N terminal region HEAT PF02985.17 EXF82164.1 - 0.16 12.0 4.7 12 6.3 0.1 5.4 6 0 0 6 6 6 0 HEAT repeat Zn_clus PF00172.13 EXF82165.1 - 6.5e-08 32.3 13.9 6.5e-08 32.3 9.6 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BACON PF13004.2 EXF82165.1 - 0.072 13.3 0.5 0.3 11.3 0.0 2.3 3 0 0 3 3 3 0 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal VCBS PF13517.1 EXF82165.1 - 0.076 13.3 0.1 0.21 11.9 0.1 1.8 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FAD_binding_4 PF01565.18 EXF82166.1 - 8.5e-19 67.4 1.6 1.3e-18 66.7 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF82166.1 - 2.5e-07 30.4 0.0 4.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like MFS_1 PF07690.11 EXF82167.1 - 3.8e-40 137.6 50.2 3.8e-40 137.6 34.8 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF82167.1 - 4.1e-09 35.5 10.8 4.1e-09 35.5 7.5 3.1 2 1 0 2 2 2 1 Sugar (and other) transporter Fungal_trans PF04082.13 EXF82168.1 - 5.5e-17 61.5 0.5 1.2e-16 60.3 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Cupin_2 PF07883.6 EXF82169.1 - 4.1e-10 39.0 0.2 5.9e-10 38.5 0.1 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EXF82169.1 - 0.018 14.4 0.1 0.025 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Toxin_3 PF00537.13 EXF82170.1 - 4.4 7.2 11.1 0.4 10.6 0.3 2.5 3 0 0 3 3 3 0 Scorpion toxin-like domain Glyco_transf_5 PF08323.6 EXF82171.1 - 4.1e-16 59.2 0.1 9.2e-16 58.0 0.1 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Alpha-amylase PF00128.19 EXF82171.1 - 3.8e-14 52.8 7.9 6.5e-14 52.0 1.1 3.5 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_trans_1_4 PF13692.1 EXF82171.1 - 6.5e-07 29.5 0.0 1.9e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EXF82171.1 - 7.5e-06 25.4 0.0 1.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Big_5 PF13205.1 EXF82171.1 - 9 6.9 11.5 0.31 11.6 0.7 2.7 1 1 1 2 2 2 0 Bacterial Ig-like domain Methyltransf_23 PF13489.1 EXF82172.1 - 1.6e-21 76.6 0.1 3.6e-21 75.5 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF82172.1 - 1.2e-12 48.1 0.0 2.4e-12 47.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF82172.1 - 1.1e-11 45.3 0.0 1.7e-10 41.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF82172.1 - 4.5e-11 43.1 0.0 1e-10 41.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF82172.1 - 1.2e-10 41.1 0.0 5.8e-10 38.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF82172.1 - 1.3e-06 27.6 0.0 4.2e-06 26.0 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EXF82172.1 - 8.7e-05 22.8 0.0 0.0006 20.1 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF82172.1 - 0.0002 20.4 0.0 0.00058 18.9 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 EXF82172.1 - 0.00021 21.2 0.0 0.0022 18.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EXF82172.1 - 0.003 17.5 0.0 0.0048 16.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 EXF82172.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain DAO PF01266.19 EXF82173.1 - 9.4e-53 179.3 0.7 1.3e-52 178.9 0.5 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF82173.1 - 0.0018 18.2 0.1 0.0053 16.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EXF82173.1 - 0.0026 17.8 0.0 0.7 9.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF82173.1 - 0.017 14.9 0.1 0.4 10.4 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Sterile PF03015.14 EXF82173.1 - 0.11 12.7 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Dioxygenase_C PF00775.16 EXF82175.1 - 3.6e-08 32.8 0.0 5.7e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Dioxygenase PGC7_Stella PF15549.1 EXF82178.1 - 0.0021 18.0 0.1 0.0021 18.0 0.1 2.2 3 0 0 3 3 3 1 PGC7/Stella/Dppa3 domain PBP PF01161.15 EXF82180.1 - 4.9e-26 91.3 0.1 6.2e-26 90.9 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Galactosyl_T PF01762.16 EXF82181.1 - 1.6e-14 53.9 1.0 4.9e-14 52.3 0.7 1.7 1 1 0 1 1 1 1 Galactosyltransferase adh_short PF00106.20 EXF82182.1 - 2.4e-20 73.0 0.0 4e-20 72.4 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF82182.1 - 4.4e-12 46.0 0.0 5.8e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF82182.1 - 1.8e-05 24.3 0.0 3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EXF82182.1 - 0.0003 20.6 0.0 0.00039 20.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Methyltransf_16 PF10294.4 EXF82183.1 - 6.8e-24 84.2 0.0 1.1e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EXF82183.1 - 0.00022 20.9 0.0 0.00038 20.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF82183.1 - 0.0048 17.3 0.0 0.011 16.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain dCMP_cyt_deam_1 PF00383.17 EXF82184.1 - 2.3e-07 30.3 0.0 3.4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region DUF2888 PF11135.3 EXF82185.1 - 0.05 13.3 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2888) Zeta_toxin PF06414.7 EXF82186.1 - 4.9e-08 32.3 0.0 6.9e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin OsmC PF02566.14 EXF82187.1 - 5.6e-17 61.7 0.0 8.5e-17 61.1 0.0 1.3 1 0 0 1 1 1 1 OsmC-like protein RNA_pol_I_A49 PF06870.7 EXF82188.1 - 9.7e-80 267.9 0.2 1.2e-79 267.7 0.1 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor ECH PF00378.15 EXF82189.1 - 2.1e-27 95.8 0.0 2.4e-27 95.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Vps51 PF08700.6 EXF82190.1 - 1.4e-13 50.4 0.0 4.6e-13 48.8 0.0 1.9 1 0 0 1 1 1 1 Vps51/Vps67 CDC45 PF02724.9 EXF82190.1 - 1.9 6.4 8.4 3.1 5.7 5.8 1.2 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.7 EXF82190.1 - 2.5 7.9 8.6 4.7 7.0 6.0 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Sas10 PF09368.5 EXF82191.1 - 1.8e-29 101.7 10.5 1.8e-29 101.7 7.3 2.8 3 0 0 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.10 EXF82191.1 - 4.4e-10 39.6 0.0 4.4e-10 39.6 0.0 2.8 3 0 0 3 3 3 1 Sas10/Utp3/C1D family Filo_glycop PF01611.11 EXF82191.1 - 0.56 8.9 4.4 0.087 11.6 0.3 1.6 2 0 0 2 2 2 0 Filovirus glycoprotein adh_short PF00106.20 EXF82192.1 - 5e-23 81.8 0.3 7.8e-23 81.2 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF82192.1 - 1e-09 38.3 0.1 1.7e-09 37.6 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF82192.1 - 1.8e-07 31.1 0.0 2.6e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EXF82192.1 - 0.00034 20.7 0.1 0.00068 19.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Eno-Rase_NADH_b PF12242.3 EXF82192.1 - 0.0016 18.2 0.0 0.0033 17.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EXF82192.1 - 0.0032 17.4 0.4 0.0084 16.1 0.3 1.8 1 1 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EXF82192.1 - 0.009 15.1 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain ApbA PF02558.11 EXF82192.1 - 0.029 13.8 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.12 EXF82192.1 - 0.034 14.5 0.0 0.22 11.9 0.1 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent vATP-synt_AC39 PF01992.11 EXF82193.1 - 0.17 10.9 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 ATP synthase (C/AC39) subunit Glyoxalase PF00903.20 EXF82194.1 - 5.5e-07 29.6 2.1 0.0004 20.3 0.4 2.8 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EXF82194.1 - 0.00065 20.2 1.4 0.0051 17.3 0.1 2.2 2 1 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EXF82194.1 - 0.091 12.7 0.1 15 5.6 0.0 2.7 2 1 0 2 2 2 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAD_binding_3 PF01494.14 EXF82195.1 - 1.1e-84 284.4 0.0 1.5e-84 284.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EXF82195.1 - 4.5e-06 26.6 0.1 1.2e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF82195.1 - 0.0024 16.8 0.0 0.05 12.5 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF82195.1 - 0.0072 15.2 0.1 0.013 14.4 0.1 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EXF82195.1 - 0.034 13.2 0.1 0.059 12.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 EXF82195.1 - 0.048 13.7 1.3 0.14 12.2 0.9 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EXF82195.1 - 0.052 12.3 0.1 0.088 11.6 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain GIDA PF01134.17 EXF82195.1 - 0.062 12.1 0.3 0.11 11.3 0.2 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox PF00070.22 EXF82195.1 - 0.17 12.3 0.2 0.68 10.3 0.0 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.17 EXF82196.1 - 1.2e-55 188.8 0.0 5.5e-35 120.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Fungal_trans PF04082.13 EXF82197.1 - 2e-21 76.0 0.4 6.1e-21 74.4 0.1 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Med9 PF07544.8 EXF82197.1 - 0.046 13.4 0.1 0.15 11.8 0.1 1.8 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 FAA_hydrolase PF01557.13 EXF82198.1 - 2e-50 171.2 0.0 2.8e-50 170.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family adh_short PF00106.20 EXF82199.1 - 5.5e-24 84.9 0.2 7.4e-24 84.5 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF82199.1 - 1.2e-22 80.8 0.0 1.5e-22 80.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF82199.1 - 1.2e-08 34.8 0.1 2.1e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF82199.1 - 0.00033 20.1 0.0 0.00088 18.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EXF82200.1 - 1.6e-32 112.7 2.6 2.3e-32 112.2 1.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF82200.1 - 1.8e-24 86.8 0.0 2.1e-24 86.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF82200.1 - 5e-15 55.6 0.6 7.1e-15 55.1 0.4 1.1 1 0 0 1 1 1 1 KR domain Peripla_BP_4 PF13407.1 EXF82200.1 - 0.0022 17.3 0.2 0.0032 16.8 0.1 1.2 1 0 0 1 1 1 1 Periplasmic binding protein domain Ldh_1_N PF00056.18 EXF82200.1 - 0.022 14.5 1.2 0.048 13.4 0.0 1.9 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EXF82200.1 - 0.12 12.1 2.1 0.33 10.7 1.4 1.7 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Cupin_2 PF07883.6 EXF82201.1 - 3.7e-08 32.7 0.1 7.7e-08 31.7 0.1 1.5 1 0 0 1 1 1 1 Cupin domain Cupin_3 PF05899.7 EXF82201.1 - 3.4e-05 23.1 0.3 0.00013 21.2 0.1 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF861) DUF605 PF04652.11 EXF82203.1 - 0.05 13.0 12.9 0.065 12.6 9.0 1.2 1 0 0 1 1 1 0 Vta1 like FLO_LFY PF01698.11 EXF82203.1 - 0.49 9.1 4.3 0.65 8.7 3.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein PBP1_TM PF14812.1 EXF82203.1 - 2.2 8.6 12.2 4.1 7.7 8.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal BLVR PF06375.6 EXF82203.1 - 2.5 7.9 13.0 3.7 7.3 8.6 1.5 1 1 0 1 1 1 0 Bovine leukaemia virus receptor (BLVR) Macoilin PF09726.4 EXF82203.1 - 4.6 5.3 7.4 5.7 5.0 5.1 1.1 1 0 0 1 1 1 0 Transmembrane protein UPF0560 PF10577.4 EXF82203.1 - 5.1 5.2 9.4 6.6 4.8 6.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 WD40 PF00400.27 EXF82204.1 - 0.047 13.5 0.9 0.57 10.1 0.3 2.6 2 0 0 2 2 2 0 WD domain, G-beta repeat Nup88 PF10168.4 EXF82204.1 - 0.07 10.9 9.6 0.3 8.8 0.0 2.4 2 1 0 2 2 2 0 Nuclear pore component GAS PF13851.1 EXF82204.1 - 0.34 10.0 13.5 0.66 9.1 9.4 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding RRM_1 PF00076.17 EXF82205.1 - 1.8e-16 59.4 0.6 2.5e-16 59.0 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF82205.1 - 3.9e-13 49.1 0.0 7.1e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF82205.1 - 7.1e-09 35.3 0.1 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EPSP_synthase PF00275.15 EXF82206.1 - 2.9e-128 427.8 0.0 6.5e-128 426.7 0.0 1.6 2 0 0 2 2 2 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) DHQ_synthase PF01761.15 EXF82206.1 - 9.1e-99 329.6 0.0 1.5e-98 328.9 0.0 1.3 1 0 0 1 1 1 1 3-dehydroquinate synthase DHquinase_I PF01487.10 EXF82206.1 - 9.1e-62 208.6 0.0 1.5e-61 207.9 0.0 1.4 1 0 0 1 1 1 1 Type I 3-dehydroquinase SKI PF01202.17 EXF82206.1 - 2.1e-37 128.4 0.0 1e-35 122.9 0.0 2.4 2 0 0 2 2 2 1 Shikimate kinase Shikimate_dh_N PF08501.6 EXF82206.1 - 7e-22 77.2 0.0 1.5e-21 76.2 0.0 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Fe-ADH_2 PF13685.1 EXF82206.1 - 1e-09 38.0 0.0 2.8e-09 36.6 0.0 1.7 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Shikimate_DH PF01488.15 EXF82206.1 - 1.1e-05 25.4 0.0 3.1e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_17 PF13207.1 EXF82206.1 - 0.00049 20.9 0.0 0.0012 19.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EXF82206.1 - 0.045 13.9 0.0 0.24 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EXF82206.1 - 0.15 11.9 0.0 0.44 10.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EXF82206.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain zf-C2H2 PF00096.21 EXF82207.1 - 1.6e-05 24.9 28.4 0.0091 16.2 0.9 4.8 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF82207.1 - 0.0014 18.8 24.4 0.0023 18.1 1.5 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-BED PF02892.10 EXF82207.1 - 0.6 9.9 3.4 1.8 8.3 2.3 1.9 1 0 0 1 1 1 0 BED zinc finger L31 PF09784.4 EXF82208.1 - 8.1e-23 80.4 0.0 1.6e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L31 Sedlin_N PF04628.8 EXF82209.1 - 3.5e-43 146.6 0.0 4e-43 146.4 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EXF82209.1 - 0.00029 20.5 0.2 0.017 14.8 0.0 2.2 1 1 1 2 2 2 2 Sybindin-like family Histone PF00125.19 EXF82210.1 - 1.8e-15 56.7 0.1 2.2e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.12 EXF82210.1 - 0.00012 21.9 0.1 0.00017 21.4 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.1 EXF82210.1 - 0.00012 22.1 0.1 0.00017 21.7 0.0 1.4 1 1 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EXF82210.1 - 0.00033 20.6 0.1 0.00059 19.8 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EXF82210.1 - 0.013 15.2 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Bromodomain associated CENP-T PF15511.1 EXF82210.1 - 0.022 14.0 0.0 0.022 14.0 0.0 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Histone PF00125.19 EXF82211.1 - 3.6e-31 107.0 0.4 5.8e-31 106.4 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EXF82211.1 - 4.1e-06 26.8 0.0 6.2e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EXF82211.1 - 0.004 17.1 0.3 0.0074 16.3 0.0 1.5 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EXF82211.1 - 0.014 15.1 0.1 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated PRP3 PF08572.5 EXF82212.1 - 6.7e-65 218.5 7.8 1.4e-64 217.5 5.4 1.5 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EXF82212.1 - 1.3e-37 128.3 2.4 2.6e-37 127.3 1.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) BLUF PF04940.7 EXF82212.1 - 0.015 14.9 0.7 6 6.6 0.0 3.0 3 0 0 3 3 3 0 Sensors of blue-light using FAD RNA_pol_Rpb1_5 PF04998.12 EXF82213.1 - 1.7e-85 286.6 0.0 3.3e-85 285.7 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EXF82213.1 - 7.3e-64 214.7 0.1 1.8e-63 213.4 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.7 EXF82213.1 - 1e-33 117.0 3.3 6.3e-22 78.2 0.0 2.5 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.13 EXF82213.1 - 2.2e-33 115.2 0.0 6.6e-33 113.6 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EXF82213.1 - 1.9e-16 59.7 0.2 1e-15 57.3 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 TPR_1 PF00515.23 EXF82214.1 - 2e-44 147.4 15.5 3.5e-07 29.5 0.1 10.5 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_11 PF13414.1 EXF82214.1 - 7.1e-40 134.5 21.8 1.3e-11 44.0 0.7 7.5 4 2 2 7 7 7 7 TPR repeat TPR_2 PF07719.12 EXF82214.1 - 1.4e-36 121.4 24.9 3.9e-05 23.2 0.0 11.0 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_8 PF13181.1 EXF82214.1 - 7.9e-32 106.6 1.2 1.7e-05 24.2 0.0 9.4 10 0 0 10 10 9 7 Tetratricopeptide repeat Apc3 PF12895.2 EXF82214.1 - 3e-30 104.2 14.7 4.9e-21 74.6 0.1 5.5 4 1 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EXF82214.1 - 4e-24 82.7 8.9 0.093 12.9 0.0 10.4 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_12 PF13424.1 EXF82214.1 - 7.2e-24 83.5 22.3 8e-06 25.7 0.1 8.0 4 2 4 8 8 8 7 Tetratricopeptide repeat TPR_19 PF14559.1 EXF82214.1 - 3.4e-23 81.7 9.5 2.9e-05 24.2 0.3 7.3 6 2 1 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.1 EXF82214.1 - 1.9e-22 79.3 21.0 9.8e-06 26.1 0.3 8.2 5 3 2 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 EXF82214.1 - 6.2e-21 72.9 15.6 0.1 13.2 0.0 11.0 4 2 7 11 11 11 6 Tetratricopeptide repeat TPR_7 PF13176.1 EXF82214.1 - 1.7e-20 71.0 9.9 0.039 13.7 0.0 9.1 10 0 0 10 10 8 5 Tetratricopeptide repeat TPR_6 PF13174.1 EXF82214.1 - 3.7e-11 42.7 10.5 1.1 9.8 0.0 9.1 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_15 PF13429.1 EXF82214.1 - 9.4e-07 28.1 13.0 0.11 11.4 0.1 5.0 3 1 1 5 5 5 4 Tetratricopeptide repeat DUF2225 PF09986.4 EXF82214.1 - 4.3e-05 23.0 4.4 0.041 13.3 1.2 3.4 2 1 1 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2225) TPR_9 PF13371.1 EXF82214.1 - 0.00058 19.6 11.2 16 5.4 0.1 6.4 5 2 2 7 7 7 0 Tetratricopeptide repeat MIT PF04212.13 EXF82214.1 - 0.042 13.7 0.8 5.9 6.8 0.2 4.0 5 0 0 5 5 3 0 MIT (microtubule interacting and transport) domain Fis1_TPR_C PF14853.1 EXF82214.1 - 0.071 13.0 2.3 17 5.3 0.0 5.4 6 0 0 6 6 5 0 Fis1 C-terminal tetratricopeptide repeat EIF_2_alpha PF07541.7 EXF82214.1 - 0.38 10.4 1.7 6.2 6.5 0.0 3.3 3 1 0 3 3 3 0 Eukaryotic translation initiation factor 2 alpha subunit TPR_4 PF07721.9 EXF82214.1 - 0.49 10.9 8.7 7.1 7.3 0.0 4.4 5 0 0 5 5 3 0 Tetratricopeptide repeat TFIIA PF03153.8 EXF82214.1 - 4.9 6.9 7.2 8.7 6.1 5.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF788 PF05620.6 EXF82215.1 - 2.4e-45 154.4 0.0 2.6e-45 154.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) Tic20 PF09685.5 EXF82215.1 - 0.051 13.5 3.8 0.48 10.4 0.2 2.0 2 0 0 2 2 2 0 Tic20-like protein 2TM PF13239.1 EXF82215.1 - 0.97 9.5 7.4 0.6 10.2 0.2 2.3 2 0 0 2 2 2 0 2TM domain DUF3605 PF12239.3 EXF82216.1 - 3.1e-58 196.1 0.0 3.7e-58 195.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) EBP PF05241.7 EXF82217.1 - 1.6e-59 200.1 7.8 2e-59 199.8 5.4 1.1 1 0 0 1 1 1 1 Emopamil binding protein DUF1129 PF06570.6 EXF82217.1 - 0.088 12.1 0.9 0.25 10.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) Fungal_trans_2 PF11951.3 EXF82219.1 - 0.00017 20.3 0.0 0.00018 20.2 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain GIDE PF12483.3 EXF82219.1 - 0.087 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 E3 Ubiquitin ligase p450 PF00067.17 EXF82220.1 - 4.2e-60 203.5 0.0 6.5e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EXF82220.1 - 6.6e-12 44.8 1.0 1.1e-11 44.1 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF82220.1 - 3.2e-05 23.7 10.5 6.4e-05 22.7 7.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FAD-oxidase_C PF02913.14 EXF82221.1 - 1.5e-29 103.0 0.0 2.1e-29 102.6 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EXF82221.1 - 5.3e-25 87.5 0.0 9.3e-25 86.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Abhydrolase_6 PF12697.2 EXF82222.1 - 7.9e-22 78.2 2.3 1.3e-21 77.5 1.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF82222.1 - 2.5e-13 50.0 0.8 7.4e-13 48.4 0.5 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF82222.1 - 7.7e-07 28.8 0.0 1.3e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EXF82222.1 - 2.2e-06 27.3 0.0 5.3e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase UPF0227 PF05728.7 EXF82222.1 - 0.052 13.2 0.0 0.89 9.2 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) DLH PF01738.13 EXF82222.1 - 0.059 12.6 0.0 0.32 10.2 0.0 2.1 2 1 0 2 2 2 0 Dienelactone hydrolase family Lipase_3 PF01764.20 EXF82222.1 - 0.075 12.6 0.1 0.18 11.4 0.0 1.7 2 0 0 2 2 2 0 Lipase (class 3) adh_short PF00106.20 EXF82224.1 - 4.4e-22 78.7 2.6 7.7e-22 77.9 1.8 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF82224.1 - 4.5e-14 52.7 0.0 5.3e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF82224.1 - 0.00032 20.4 1.0 0.00092 18.9 0.7 1.6 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF82224.1 - 0.0056 16.1 0.0 0.0086 15.5 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_26 PF13659.1 EXF82224.1 - 0.2 11.7 1.8 0.25 11.3 1.3 1.6 1 1 0 1 1 1 0 Methyltransferase domain DCP2 PF05026.8 EXF82225.1 - 6.5e-36 122.1 0.1 1.3e-35 121.1 0.1 1.5 1 0 0 1 1 1 1 Dcp2, box A domain NUDIX PF00293.23 EXF82225.1 - 6.1e-16 58.2 0.0 1.2e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF4112 PF13430.1 EXF82226.1 - 6.4e-35 119.2 0.2 8.4e-35 118.9 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4112) Ribonuc_red_sm PF00268.16 EXF82227.1 - 2.2e-120 400.9 2.1 2.7e-120 400.6 1.4 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain SRP9-21 PF05486.7 EXF82228.1 - 1.5e-13 50.2 0.0 2.2e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Mito_carr PF00153.22 EXF82229.1 - 1.1e-47 159.6 1.1 2.4e-17 62.4 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2392 PF10288.4 EXF82230.1 - 1.2e-17 64.1 0.0 2.3e-11 43.9 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF2392) DZR PF12773.2 EXF82230.1 - 0.095 12.5 5.1 3.6 7.4 0.8 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-FPG_IleRS PF06827.9 EXF82230.1 - 1.1 8.9 8.0 2.8 7.6 4.5 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS APH PF01636.18 EXF82231.1 - 2.1e-09 37.4 0.0 2.5e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EXF82231.1 - 2.9e-06 27.0 0.0 4.2e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase EcKinase PF02958.15 EXF82231.1 - 1.9e-05 23.9 0.1 2.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Ecdysteroid kinase PH PF00169.24 EXF82232.1 - 2.5e-26 91.8 2.4 4.7e-16 58.8 0.3 2.2 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EXF82232.1 - 4.5e-10 39.7 6.3 2.7e-06 27.6 0.2 3.6 2 2 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 EXF82232.1 - 3e-08 33.8 2.3 2.7e-05 24.2 0.4 3.5 2 2 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EXF82232.1 - 7.5e-06 25.9 0.2 1.6e-05 24.8 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EXF82232.1 - 0.01 15.7 1.5 0.024 14.4 0.2 2.2 2 2 0 2 2 2 0 PH domain Rota_VP2 PF05087.7 EXF82232.1 - 0.12 10.3 0.5 0.16 9.8 0.3 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein Cellulase PF00150.13 EXF82233.1 - 1.6e-19 70.1 1.2 3.1e-19 69.2 0.8 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) efThoc1 PF11957.3 EXF82234.1 - 6.1e-161 536.2 6.1 6.1e-161 536.2 4.2 1.4 2 0 0 2 2 2 1 THO complex subunit 1 transcription elongation factor Guanylate_kin PF00625.16 EXF82234.1 - 3.3e-31 108.1 0.0 7.9e-31 106.9 0.0 1.7 1 0 0 1 1 1 1 Guanylate kinase AAA_33 PF13671.1 EXF82234.1 - 3.5e-06 26.9 0.0 1.8e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EXF82234.1 - 4.5e-05 23.7 0.0 0.00022 21.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EXF82234.1 - 5.5e-05 23.1 0.0 0.00026 21.0 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EXF82234.1 - 0.00022 22.0 0.4 0.0017 19.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EXF82234.1 - 0.00098 19.2 0.0 0.0041 17.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EXF82234.1 - 0.0039 17.3 0.0 0.91 9.7 0.0 2.8 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.7 EXF82234.1 - 0.0078 15.3 0.0 0.02 14.0 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.1 EXF82234.1 - 0.008 16.1 0.4 0.041 13.8 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EXF82234.1 - 0.0091 15.7 0.1 0.036 13.8 0.0 2.0 2 0 0 2 2 2 1 Part of AAA domain AAA PF00004.24 EXF82234.1 - 0.0098 16.0 0.0 0.027 14.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EXF82234.1 - 0.024 14.3 0.0 0.11 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EXF82234.1 - 0.027 13.5 0.0 0.082 11.9 0.0 1.7 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus MMR_HSR1 PF01926.18 EXF82234.1 - 0.031 14.2 0.0 0.089 12.7 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EXF82234.1 - 0.053 13.8 0.0 0.18 12.0 0.0 2.0 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 EXF82234.1 - 0.062 12.9 0.0 0.22 11.1 0.0 2.0 1 0 0 1 1 1 0 NACHT domain IstB_IS21 PF01695.12 EXF82234.1 - 0.09 12.1 0.0 0.23 10.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_12 PF13087.1 EXF82235.1 - 7.2e-27 94.0 0.0 1.4e-26 93.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EXF82235.1 - 4.5e-22 78.7 0.0 1.2e-21 77.4 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EXF82235.1 - 2.2e-09 36.9 0.1 4.5e-08 32.7 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_30 PF13604.1 EXF82235.1 - 7.1e-07 29.0 0.0 0.00048 19.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain ResIII PF04851.10 EXF82235.1 - 0.00021 21.2 0.0 0.00043 20.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.24 EXF82235.1 - 0.002 18.3 0.0 0.0073 16.5 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DEAD PF00270.24 EXF82235.1 - 0.0029 17.1 0.0 0.011 15.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Viral_helicase1 PF01443.13 EXF82235.1 - 0.0044 16.5 0.2 0.31 10.5 0.0 3.1 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EXF82235.1 - 0.0045 17.1 0.0 0.019 15.1 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EXF82235.1 - 0.013 14.9 0.0 0.028 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EXF82235.1 - 0.02 14.0 0.0 0.06 12.4 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.1 EXF82235.1 - 0.023 14.6 0.0 0.12 12.3 0.0 2.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 EXF82235.1 - 0.037 14.8 0.1 1.1 10.0 0.0 3.3 3 0 0 3 3 3 0 AAA domain DnaB_C PF03796.10 EXF82235.1 - 0.044 12.6 0.0 0.086 11.7 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain PIF1 PF05970.9 EXF82235.1 - 0.052 12.4 0.0 1.4 7.8 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase UvrD-helicase PF00580.16 EXF82235.1 - 0.057 12.7 0.4 0.3 10.3 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain DUF2075 PF09848.4 EXF82235.1 - 0.098 11.6 0.7 0.14 11.0 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EXF82235.1 - 0.18 10.5 0.0 0.32 9.8 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain MIF4G PF02854.14 EXF82236.1 - 2.4e-51 174.1 0.0 4e-51 173.4 0.0 1.4 1 0 0 1 1 1 1 MIF4G domain eIF_4G1 PF12152.3 EXF82236.1 - 2.4e-22 78.5 1.0 7e-22 77.1 0.7 1.9 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4G1 DNA_pol_B PF00136.16 EXF82237.1 - 1.3e-115 386.8 1.1 2e-115 386.2 0.7 1.3 1 0 0 1 1 1 1 DNA polymerase family B zf-DNA_Pol PF08996.5 EXF82237.1 - 8.9e-67 224.0 1.0 1.5e-66 223.3 0.3 1.7 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.14 EXF82237.1 - 9.3e-42 143.0 0.0 2.4e-41 141.6 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.3 EXF82237.1 - 7.2e-22 76.9 10.8 7.2e-22 76.9 7.5 2.4 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal PPR_2 PF13041.1 EXF82238.1 - 2.5e-22 78.5 1.3 2e-13 50.0 0.0 5.7 5 1 1 6 6 6 3 PPR repeat family PPR_3 PF13812.1 EXF82238.1 - 2.3e-10 39.9 3.9 0.53 10.6 0.0 7.9 8 1 1 9 9 9 3 Pentatricopeptide repeat domain PPR PF01535.15 EXF82238.1 - 2.7e-07 30.0 6.4 1.4 9.0 0.0 7.3 8 1 0 8 8 8 2 PPR repeat PPR_1 PF12854.2 EXF82238.1 - 0.00078 18.8 3.4 29 4.2 0.0 5.9 6 0 0 6 6 6 0 PPR repeat ERAP1_C PF11838.3 EXF82238.1 - 0.0016 17.7 0.7 0.0066 15.7 0.0 2.3 2 1 1 3 3 3 1 ERAP1-like C-terminal domain ATP13 PF12921.2 EXF82238.1 - 0.0084 15.4 0.3 0.14 11.5 0.0 2.9 3 0 0 3 3 3 1 Mitochondrial ATPase expression TPR_14 PF13428.1 EXF82238.1 - 0.34 11.6 3.3 63 4.6 0.0 4.5 4 1 1 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.20 EXF82240.1 - 8e-53 179.2 0.0 1.9e-52 178.0 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF82240.1 - 1.2e-23 83.5 0.0 2.8e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EXF82240.1 - 0.00047 19.9 2.3 0.0005 19.8 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EXF82240.1 - 0.0031 16.8 0.2 0.01 15.1 0.1 1.7 1 1 0 1 1 1 1 RIO1 family DUF4430 PF14478.1 EXF82240.1 - 0.091 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) CoaE PF01121.15 EXF82241.1 - 4.4e-43 146.7 0.0 1.9e-42 144.6 0.0 1.8 1 1 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 EXF82241.1 - 0.0052 17.0 0.1 0.27 11.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EXF82241.1 - 0.0067 17.2 0.3 0.02 15.7 0.0 1.9 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EXF82241.1 - 0.089 12.6 0.0 0.49 10.2 0.0 2.2 1 1 0 1 1 1 0 AAA domain RRM_1 PF00076.17 EXF82242.1 - 3.4e-60 199.5 0.0 2.5e-21 75.0 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF82242.1 - 2.5e-43 145.9 0.0 1.1e-14 54.1 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF82242.1 - 9.4e-31 105.4 0.0 9.1e-11 41.4 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EXF82242.1 - 2.6e-07 30.2 0.0 0.0084 15.8 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Cas_Cas2CT1978 PF09707.5 EXF82242.1 - 0.00035 20.4 0.0 0.97 9.4 0.0 2.4 2 0 0 2 2 2 2 CRISPR-associated protein (Cas_Cas2CT1978) RRM_3 PF08777.6 EXF82242.1 - 0.039 13.8 0.0 0.94 9.3 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif LON PF02190.11 EXF82244.1 - 8.3e-28 97.4 0.0 1.7e-27 96.4 0.0 1.5 2 0 0 2 2 2 1 ATP-dependent protease La (LON) domain zf-C3HC4_4 PF15227.1 EXF82244.1 - 8.5e-05 22.3 4.5 0.00019 21.2 3.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EXF82244.1 - 0.037 14.0 6.5 0.087 12.8 4.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EXF82244.1 - 0.068 13.0 3.5 0.18 11.6 2.4 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 EXF82244.1 - 0.077 12.7 5.5 0.15 11.7 3.8 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.20 EXF82244.1 - 0.1 12.2 2.7 0.27 10.9 1.9 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) INSIG PF07281.7 EXF82246.1 - 9.2e-54 181.7 0.2 1.2e-53 181.3 0.1 1.1 1 0 0 1 1 1 1 Insulin-induced protein (INSIG) WD40 PF00400.27 EXF82247.1 - 1.8e-16 59.2 1.5 0.00059 19.6 0.0 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EXF82247.1 - 0.0001 21.1 0.1 0.00038 19.3 0.0 1.9 2 0 0 2 2 2 1 Nup133 N terminal like Nup160 PF11715.3 EXF82247.1 - 0.061 11.4 0.0 0.28 9.2 0.0 1.8 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Pkinase PF00069.20 EXF82248.1 - 6.2e-38 130.4 0.0 9.1e-38 129.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF82248.1 - 5.6e-27 94.4 0.0 8.6e-27 93.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF82248.1 - 0.0077 15.2 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EXF82248.1 - 0.06 12.4 0.0 0.1 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AA_permease PF00324.16 EXF82249.1 - 4.2e-136 454.0 38.9 5.2e-136 453.7 27.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF82249.1 - 1.9e-40 138.7 43.1 2.4e-40 138.3 29.9 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1749 PF08538.5 EXF82251.1 - 5.6e-87 291.4 0.0 6.2e-87 291.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Abhydrolase_6 PF12697.2 EXF82251.1 - 8.1e-16 58.5 0.0 1.1e-15 58.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF82251.1 - 2e-10 40.5 0.0 5.1e-10 39.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF82251.1 - 3e-05 23.6 0.0 0.0012 18.4 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EXF82251.1 - 0.00018 20.8 0.0 0.036 13.2 0.0 2.5 3 0 0 3 3 3 2 Prolyl oligopeptidase family Ser_hydrolase PF06821.8 EXF82251.1 - 0.017 14.7 0.0 0.058 13.0 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase Abhydrolase_2 PF02230.11 EXF82251.1 - 0.019 14.4 0.0 1.5 8.2 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2305 PF10230.4 EXF82251.1 - 0.037 13.4 0.0 0.86 8.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2305) LCAT PF02450.10 EXF82251.1 - 0.094 11.6 0.1 0.83 8.5 0.0 2.0 1 1 1 2 2 2 0 Lecithin:cholesterol acyltransferase p450 PF00067.17 EXF82253.1 - 1.5e-48 165.5 0.0 4.5e-48 163.9 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 eIF-5_eIF-2B PF01873.12 EXF82254.1 - 4.4e-40 136.2 0.0 8.4e-40 135.3 0.0 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EXF82254.1 - 1.9e-24 85.4 2.9 1.9e-24 85.4 2.0 2.1 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Zn-ribbon_8 PF09723.5 EXF82254.1 - 0.3 11.0 1.0 0.7 9.8 0.7 1.6 1 0 0 1 1 1 0 Zinc ribbon domain DUF3311 PF11755.3 EXF82255.1 - 2.5 7.6 4.0 5 6.7 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3311) Tim17 PF02466.14 EXF82257.1 - 4.3e-26 91.4 4.5 5.7e-26 91.0 3.1 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family 5TM-5TMR_LYT PF07694.7 EXF82257.1 - 0.054 12.8 1.1 0.083 12.2 0.8 1.2 1 0 0 1 1 1 0 5TMR of 5TMR-LYT MARVEL PF01284.18 EXF82258.1 - 2.4e-20 72.8 0.4 3.3e-20 72.3 0.3 1.1 1 0 0 1 1 1 1 Membrane-associating domain QCR10 PF09796.4 EXF82258.1 - 0.069 12.8 3.5 3.6 7.3 0.1 2.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF4064 PF13273.1 EXF82258.1 - 0.23 11.6 3.6 0.85 9.7 1.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) DUF1469 PF07332.6 EXF82258.1 - 1.2 8.8 9.6 0.4 10.4 1.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) DUF2834 PF11196.3 EXF82259.1 - 0.011 15.9 2.4 0.22 11.6 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2834) IL8 PF00048.15 EXF82262.1 - 0.029 14.3 0.2 0.083 12.8 0.2 1.8 1 0 0 1 1 1 0 Small cytokines (intecrine/chemokine), interleukin-8 like MAP7 PF05672.6 EXF82262.1 - 0.03 13.6 1.0 0.05 12.9 0.7 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family Stn1_C PF12659.2 EXF82262.1 - 0.049 13.4 0.8 7.4 6.3 0.2 2.5 2 1 0 2 2 2 0 Telomere capping C-terminal wHTH Cas1_AcylT PF07779.7 EXF82263.1 - 2.6e-62 210.8 20.6 4.2e-61 206.9 14.3 2.5 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p PC-Esterase PF13839.1 EXF82263.1 - 7.3e-19 68.6 0.0 1.4e-18 67.7 0.0 1.5 1 0 0 1 1 1 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p SPX PF03105.14 EXF82263.1 - 0.00033 20.5 0.2 0.00054 19.8 0.1 1.3 1 0 0 1 1 1 1 SPX domain Ribosomal_S13 PF00416.17 EXF82264.1 - 1.1e-35 122.3 1.0 2.1e-24 86.0 0.2 2.1 1 1 1 2 2 2 2 Ribosomal protein S13/S18 PP28 PF10252.4 EXF82264.1 - 0.069 13.1 0.6 0.15 12.0 0.4 1.6 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 SBDS_C PF09377.5 EXF82265.1 - 8.3e-51 170.9 0.0 1.3e-50 170.3 0.0 1.3 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.13 EXF82265.1 - 2.7e-30 104.0 0.3 4.2e-30 103.3 0.2 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Peptidase_S10 PF00450.17 EXF82266.1 - 8.3e-130 433.6 1.6 1.1e-129 433.2 1.1 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Carbpep_Y_N PF05388.6 EXF82266.1 - 3.9e-06 26.9 0.1 7.4e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Carboxypeptidase Y pro-peptide Abhydrolase_6 PF12697.2 EXF82266.1 - 0.00011 22.1 0.0 0.00051 19.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family PDEase_I PF00233.14 EXF82268.1 - 3e-43 148.3 1.0 4.6e-40 137.8 0.0 2.2 2 0 0 2 2 2 2 3'5'-cyclic nucleotide phosphodiesterase Adaptin_N PF01602.15 EXF82269.1 - 7.4e-132 440.3 9.6 9e-132 440.0 6.6 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EXF82269.1 - 7.9e-18 64.9 2.7 1.5e-17 64.0 0.1 2.6 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EXF82269.1 - 9.2e-16 57.9 5.6 4.5e-10 39.6 0.1 4.4 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 EXF82269.1 - 1.1e-11 43.7 3.1 0.00045 20.0 0.0 4.9 5 0 0 5 5 5 3 HEAT repeat CLASP_N PF12348.3 EXF82269.1 - 1.4e-05 24.5 0.2 0.021 14.1 0.0 2.8 2 0 0 2 2 2 2 CLASP N terminal HEAT_EZ PF13513.1 EXF82269.1 - 3.1e-05 24.3 6.0 0.77 10.3 0.0 6.0 5 1 1 6 6 6 1 HEAT-like repeat Atx10homo_assoc PF09759.4 EXF82269.1 - 0.0002 21.0 0.1 0.31 10.8 0.0 4.3 4 1 0 4 4 4 1 Spinocerebellar ataxia type 10 protein domain Arm PF00514.18 EXF82269.1 - 0.017 14.9 1.1 6.1 6.8 0.0 4.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat DUF2435 PF10363.4 EXF82269.1 - 0.15 11.9 2.2 2.1 8.2 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2435) DUF1077 PF06417.7 EXF82270.1 - 3e-54 181.6 5.2 3.9e-54 181.3 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) MFS_1 PF07690.11 EXF82272.1 - 6.7e-46 156.6 19.6 6.7e-46 156.6 13.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF82272.1 - 9e-11 40.9 0.9 9e-11 40.9 0.6 2.5 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.8 EXF82272.1 - 0.17 9.9 17.6 0.004 15.3 5.1 2.4 3 0 0 3 3 3 0 Transmembrane secretion effector OATP PF03137.15 EXF82272.1 - 3.3 5.6 8.1 0.096 10.7 0.8 1.7 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Syntaxin-18_N PF10496.4 EXF82273.1 - 8.8e-16 57.5 0.2 3.2e-15 55.7 0.1 2.1 1 0 0 1 1 1 1 SNARE-complex protein Syntaxin-18 N-terminus DUF1917 PF08939.5 EXF82273.1 - 0.0085 15.8 3.4 0.018 14.7 2.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) SNARE PF05739.14 EXF82273.1 - 0.02 14.5 2.5 0.071 12.8 0.1 2.9 3 0 0 3 3 3 0 SNARE domain Nop25 PF09805.4 EXF82273.1 - 0.26 11.3 4.3 0.81 9.7 3.0 1.8 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) CENP-H PF05837.7 EXF82273.1 - 1.8 8.7 7.1 3.3 7.9 2.0 2.6 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Aminotran_1_2 PF00155.16 EXF82274.1 - 1.7e-87 293.7 0.0 2e-87 293.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Myb_DNA-binding PF00249.26 EXF82274.1 - 0.045 13.8 0.1 11 6.1 0.0 2.4 2 0 0 2 2 2 0 Myb-like DNA-binding domain Sugar_tr PF00083.19 EXF82275.1 - 9.3e-79 265.0 22.3 1.1e-78 264.8 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF82275.1 - 2.3e-24 85.7 22.4 2.3e-24 85.7 15.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EXF82275.1 - 4.4e-06 25.3 1.5 4.4e-06 25.3 1.0 3.4 2 2 2 4 4 4 1 MFS/sugar transport protein TRI12 PF06609.8 EXF82275.1 - 0.00096 17.4 1.1 0.0015 16.8 0.8 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) ATP_synt_H PF05493.8 EXF82275.1 - 3.1 7.9 9.8 3.6 7.7 3.2 3.1 2 0 0 2 2 2 0 ATP synthase subunit H Ank_2 PF12796.2 EXF82276.1 - 4e-104 341.1 36.8 4.9e-20 71.6 0.3 9.6 1 1 11 12 12 12 11 Ankyrin repeats (3 copies) Ank PF00023.25 EXF82276.1 - 2.9e-74 241.3 31.2 1.1e-07 31.3 0.0 16.6 17 0 0 17 17 16 13 Ankyrin repeat Ank_4 PF13637.1 EXF82276.1 - 5.4e-58 192.4 19.0 1.7e-10 41.0 0.1 12.7 4 2 10 14 14 14 13 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF82276.1 - 1.2e-52 174.7 31.6 7.4e-07 29.2 0.8 14.1 4 3 9 14 14 14 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF82276.1 - 3.8e-47 153.5 23.3 2.3e-05 24.1 0.0 15.7 16 0 0 16 16 15 11 Ankyrin repeat ZZ PF00569.12 EXF82276.1 - 1.7e-05 24.2 7.5 5.5e-05 22.6 5.2 1.8 1 0 0 1 1 1 1 Zinc finger, ZZ type NACHT PF05729.7 EXF82276.1 - 2.7e-05 23.9 0.0 5.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_19 PF13245.1 EXF82276.1 - 0.00038 20.1 0.0 0.0011 18.6 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_33 PF13671.1 EXF82276.1 - 0.0028 17.5 0.0 0.0089 15.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EXF82276.1 - 0.0031 17.6 0.0 0.043 13.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EXF82276.1 - 0.0035 17.3 0.0 0.013 15.4 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.17 EXF82276.1 - 0.0079 16.3 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 RNA helicase NB-ARC PF00931.17 EXF82276.1 - 0.066 12.0 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Desmo_N PF06771.6 EXF82276.1 - 0.14 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Viral Desmoplakin N-terminus p450 PF00067.17 EXF82277.1 - 1.4e-43 149.1 0.0 4.2e-32 111.2 0.0 2.6 2 1 0 2 2 2 2 Cytochrome P450 F-box-like PF12937.2 EXF82278.1 - 0.039 13.6 0.0 0.09 12.5 0.0 1.7 1 0 0 1 1 1 0 F-box-like LRR_2 PF07723.8 EXF82278.1 - 0.047 14.1 0.9 16 6.2 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_7 PF13504.1 EXF82278.1 - 0.34 11.2 2.7 34 5.2 0.1 4.0 4 0 0 4 4 4 0 Leucine rich repeat Lactonase PF10282.4 EXF82279.1 - 4.9e-22 78.4 5.3 6.2e-20 71.5 1.9 2.1 1 1 1 2 2 2 2 Lactonase, 7-bladed beta-propeller SGL PF08450.7 EXF82279.1 - 0.0027 17.1 0.4 0.0089 15.4 0.2 1.8 1 1 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region VCBS PF13517.1 EXF82279.1 - 1.5 9.1 4.5 26 5.2 0.1 3.5 2 1 1 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella CorA PF01544.13 EXF82280.1 - 0.00015 20.8 0.0 0.00039 19.5 0.0 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein PetM PF08041.6 EXF82280.1 - 0.24 10.9 0.7 0.47 9.9 0.5 1.4 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 ADH_N PF08240.7 EXF82281.1 - 5.5e-14 51.8 0.1 1.7e-13 50.3 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF82281.1 - 9.9e-07 28.3 0.1 8e-06 25.4 0.1 2.1 1 1 0 1 1 1 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 EXF82281.1 - 0.012 14.1 0.0 0.016 13.6 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein AA_permease_2 PF13520.1 EXF82282.1 - 8.1e-58 195.9 54.8 1e-57 195.6 38.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF82282.1 - 2.5e-30 105.2 46.6 3.6e-30 104.7 32.3 1.1 1 0 0 1 1 1 1 Amino acid permease MatE PF01554.13 EXF82284.1 - 2.5e-52 176.7 31.8 1.9e-31 108.8 7.5 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EXF82284.1 - 5.3e-06 26.2 1.9 5.3e-06 26.2 1.3 4.7 3 2 2 5 5 5 2 Polysaccharide biosynthesis C-terminal domain Como_SCP PF02248.11 EXF82284.1 - 0.035 13.4 0.1 0.065 12.5 0.1 1.3 1 0 0 1 1 1 0 Small coat protein HET PF06985.6 EXF82285.1 - 7.4e-07 29.4 0.2 1.4e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF1768 PF08719.6 EXF82288.1 - 1.1e-45 155.2 0.1 1.4e-45 154.8 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Lumazine_bd PF12870.2 EXF82288.1 - 0.5 10.4 3.2 0.76 9.8 0.2 2.1 2 0 0 2 2 2 0 Lumazine-binding domain E1-E2_ATPase PF00122.15 EXF82289.1 - 1.3e-61 207.5 0.5 3e-61 206.3 0.3 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EXF82289.1 - 1.2e-30 107.5 0.0 5.6e-30 105.3 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EXF82289.1 - 3.3e-26 91.9 7.7 3.3e-26 91.9 5.3 2.7 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase_like2 PF13246.1 EXF82289.1 - 8.1e-16 57.7 0.0 1.7e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EXF82289.1 - 6.8e-15 54.2 0.1 6.8e-15 54.2 0.1 2.4 3 0 0 3 3 3 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EXF82289.1 - 9.2e-12 45.5 0.0 2.9e-11 43.8 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EXF82289.1 - 7.7e-06 25.6 0.2 1.4e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Glyco_hydro_cc PF11790.3 EXF82290.1 - 3.1e-22 79.1 0.1 3.8e-22 78.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Transpeptidase PF00905.17 EXF82290.1 - 0.1 11.5 0.1 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Penicillin binding protein transpeptidase domain DUF3678 PF12435.3 EXF82290.1 - 0.63 9.6 2.9 1.2 8.7 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3678) DEAD PF00270.24 EXF82291.1 - 2.8e-46 157.1 0.0 9.2e-46 155.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DBP10CT PF08147.7 EXF82291.1 - 5.4e-23 80.5 2.0 1.8e-22 78.8 1.4 2.0 1 0 0 1 1 1 1 DBP10CT (NUC160) domain Helicase_C PF00271.26 EXF82291.1 - 1.2e-22 79.5 0.1 1.8e-21 75.8 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EXF82291.1 - 0.0017 18.2 0.0 0.006 16.4 0.0 2.0 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DnaJ PF00226.26 EXF82292.1 - 1.2e-13 50.5 4.6 3.7e-13 49.0 0.4 3.0 3 0 0 3 3 3 1 DnaJ domain DUF3512 PF12024.3 EXF82292.1 - 0.11 11.7 5.8 0.11 11.8 1.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3512) Arm PF00514.18 EXF82293.1 - 6.9e-06 25.6 2.2 0.0047 16.7 0.2 4.2 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat BUD22 PF09073.5 EXF82293.1 - 0.0005 19.2 8.9 0.00092 18.3 6.2 1.3 1 0 0 1 1 1 1 BUD22 SDA1 PF05285.7 EXF82293.1 - 1.6 7.9 16.9 2.7 7.2 11.7 1.2 1 0 0 1 1 1 0 SDA1 DUF202 PF02656.10 EXF82295.1 - 2.1e-19 69.4 0.0 2.1e-19 69.4 0.0 2.9 3 1 0 3 3 3 1 Domain of unknown function (DUF202) DUF3357 PF11837.3 EXF82295.1 - 0.018 14.8 0.4 0.19 11.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) OST3_OST6 PF04756.8 EXF82295.1 - 0.029 13.9 0.9 0.048 13.2 0.7 1.3 1 1 0 1 1 1 0 OST3 / OST6 family COX4_pro_2 PF07835.7 EXF82295.1 - 0.034 14.1 1.5 0.12 12.3 0.0 2.4 2 0 0 2 2 2 0 Bacterial aa3 type cytochrome c oxidase subunit IV DUF1345 PF07077.6 EXF82295.1 - 0.084 12.3 4.4 1.3 8.5 1.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1345) Cytochrom_B_C PF00032.12 EXF82295.1 - 1 9.6 3.7 0.95 9.7 0.6 1.9 1 1 1 2 2 2 0 Cytochrome b(C-terminal)/b6/petD DNA_mis_repair PF01119.14 EXF82298.1 - 1.6e-33 114.7 0.0 2.6e-33 114.0 0.0 1.4 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EXF82298.1 - 2.4e-13 49.9 0.0 4.7e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EXF82298.1 - 1.1e-09 38.0 0.0 2.7e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Zn_clus PF00172.13 EXF82301.1 - 7.2e-07 29.0 11.7 1.2e-06 28.3 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS_4 PF08448.5 EXF82301.1 - 0.002 18.1 0.0 0.0063 16.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_11 PF14598.1 EXF82301.1 - 0.12 12.3 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 PAS domain Acetyltransf_8 PF13523.1 EXF82303.1 - 5.6e-39 133.4 1.6 8.5e-39 132.8 1.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EXF82303.1 - 0.015 15.4 0.3 0.029 14.5 0.2 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Methyltransf_18 PF12847.2 EXF82304.1 - 4.8e-09 36.7 0.0 5.9e-08 33.2 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF82304.1 - 0.00013 21.6 0.0 0.00032 20.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF82304.1 - 0.0016 18.7 0.0 0.0048 17.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EXF82304.1 - 0.0021 18.8 0.0 0.0046 17.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF82304.1 - 0.0033 17.0 0.0 0.12 11.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.7 EXF82304.1 - 0.0034 16.8 0.0 0.1 11.9 0.0 2.2 2 0 0 2 2 2 1 Methionine biosynthesis protein MetW PCMT PF01135.14 EXF82304.1 - 0.0094 15.5 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 EXF82304.1 - 0.021 15.3 0.0 1.4 9.4 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EXF82304.1 - 0.068 13.2 0.0 0.15 12.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EXF82304.1 - 0.082 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB AMP-binding PF00501.23 EXF82305.1 - 1.3e-94 316.9 0.0 1.6e-94 316.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EXF82305.1 - 6.9e-14 52.5 0.0 1.7e-13 51.2 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Acetyltransf_7 PF13508.1 EXF82306.1 - 3.2e-07 30.4 0.0 7.6e-07 29.1 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EXF82306.1 - 2.4e-06 27.4 0.2 4.5e-06 26.6 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EXF82306.1 - 0.005 16.9 0.1 0.03 14.4 0.1 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EXF82306.1 - 0.0086 15.8 0.1 0.074 12.8 0.1 2.1 1 1 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EXF82306.1 - 0.018 14.8 0.1 0.071 12.9 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AA_permease PF00324.16 EXF82307.1 - 1.6e-91 307.0 35.7 2e-91 306.7 24.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF82307.1 - 2.5e-24 85.6 40.6 2.9e-24 85.3 28.1 1.0 1 0 0 1 1 1 1 Amino acid permease DUF1772 PF08592.6 EXF82307.1 - 9.6 5.9 13.2 0.43 10.3 0.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) Inositol_P PF00459.20 EXF82308.1 - 2.3e-35 122.2 0.0 5.5e-35 120.9 0.0 1.6 1 1 0 1 1 1 1 Inositol monophosphatase family CVNH PF08881.5 EXF82309.1 - 3.8e-11 43.1 0.1 4.5e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 CVNH domain Rad4 PF03835.10 EXF82310.1 - 3.8e-15 55.5 1.7 9e-15 54.3 1.2 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Transglut_core PF01841.14 EXF82310.1 - 3.6e-11 43.2 1.6 8.9e-11 42.0 1.1 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily WD40 PF00400.27 EXF82311.1 - 2.6e-10 39.7 8.6 0.75 9.7 0.0 8.9 8 1 0 8 8 8 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EXF82311.1 - 1.8e-08 33.5 0.3 0.062 12.0 0.0 3.4 1 1 1 3 3 3 3 Nup133 N terminal like PQQ_2 PF13360.1 EXF82311.1 - 0.00013 21.5 2.8 0.0017 17.8 0.3 2.9 1 1 1 2 2 2 1 PQQ-like domain Nop14 PF04147.7 EXF82311.1 - 0.41 8.5 9.4 0.67 7.8 1.3 2.1 2 0 0 2 2 2 0 Nop14-like family NAPRTase PF04095.11 EXF82312.1 - 3.6e-56 190.1 0.1 4.9e-56 189.7 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family WSC PF01822.14 EXF82313.1 - 6.6e-19 67.6 5.3 1.7e-18 66.2 3.7 1.8 1 0 0 1 1 1 1 WSC domain COesterase PF00135.23 EXF82314.1 - 5.9e-86 289.2 0.0 8e-86 288.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF82314.1 - 2.5e-07 30.4 0.1 6.4e-07 29.1 0.1 1.8 1 0 0 1 1 1 1 alpha/beta hydrolase fold Meleagrin PF08189.6 EXF82315.1 - 0.14 11.6 1.1 0.39 10.2 0.8 1.7 1 0 0 1 1 1 0 Meleagrin/Cygnin family AF-4 PF05110.8 EXF82315.1 - 1.6 6.4 7.2 1.9 6.2 5.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Period_C PF12114.3 EXF82315.1 - 5.1 6.6 5.9 7.3 6.1 4.1 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Glyco_hydro_18 PF00704.23 EXF82317.1 - 2.5e-16 60.0 1.2 7.9e-16 58.4 0.9 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Sporozoite_P67 PF05642.6 EXF82317.1 - 0.62 7.8 2.4 0.82 7.4 1.6 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Abhydrolase_6 PF12697.2 EXF82318.1 - 1.1e-18 68.0 1.4 2.3e-18 66.9 0.5 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family ADH_N PF08240.7 EXF82318.1 - 4e-09 36.2 0.0 7.8e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Abhydrolase_5 PF12695.2 EXF82318.1 - 2.1e-07 30.7 0.0 7.9e-07 28.9 0.0 2.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF82318.1 - 3.2e-06 26.8 0.0 8e-06 25.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF1057 PF06342.7 EXF82318.1 - 0.11 11.2 0.0 0.25 10.1 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Methyltransf_23 PF13489.1 EXF82319.1 - 1.8e-23 83.0 0.0 2.8e-23 82.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF82319.1 - 1.1e-11 44.5 0.1 7.9e-11 41.7 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF82319.1 - 3.6e-10 40.4 0.1 6.3e-09 36.4 0.1 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF82319.1 - 9.5e-10 38.8 0.0 1.6e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF82319.1 - 7.3e-08 32.8 0.1 1e-06 29.1 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF82319.1 - 7.4e-06 26.2 0.0 1.6e-05 25.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EXF82319.1 - 0.00034 19.8 0.0 0.0006 19.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EXF82319.1 - 0.0015 18.5 0.0 0.0038 17.2 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF82319.1 - 0.0049 16.2 0.0 0.01 15.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain DUF4440 PF14534.1 EXF82319.1 - 0.0075 16.4 0.0 0.95 9.7 0.0 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) FtsJ PF01728.14 EXF82319.1 - 0.036 14.0 0.1 0.088 12.7 0.1 1.6 1 1 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.15 EXF82319.1 - 0.045 12.8 0.0 0.061 12.4 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DREV PF05219.7 EXF82319.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase Ubie_methyltran PF01209.13 EXF82319.1 - 0.16 11.0 0.0 1.4 8.0 0.0 2.4 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EXF82319.1 - 0.18 11.3 0.0 0.4 10.1 0.0 1.7 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EXF82319.1 - 0.19 10.7 2.4 0.37 9.8 0.0 2.3 3 0 0 3 3 3 0 Putative methyltransferase DNase_NucA_NucB PF14040.1 EXF82320.1 - 8.9e-05 22.6 1.2 0.0059 16.7 0.1 2.7 2 0 0 2 2 2 2 Deoxyribonuclease NucA/NucB zf-RanBP PF00641.13 EXF82322.1 - 0.042 12.9 1.5 0.042 12.9 1.1 2.0 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DZR PF12773.2 EXF82322.1 - 0.078 12.8 3.5 3.2 7.6 2.6 2.4 1 1 1 2 2 2 0 Double zinc ribbon YlbD_coat PF14071.1 EXF82323.1 - 0.051 13.6 0.2 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 Putative coat protein Mpv17_PMP22 PF04117.7 EXF82324.1 - 1e-26 92.2 1.1 1.9e-26 91.4 0.8 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family DUF1281 PF06924.6 EXF82324.1 - 0.036 13.4 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1281) DUF1713 PF08213.6 EXF82325.1 - 2.1e-11 43.2 23.3 2.1e-11 43.2 16.2 1.7 2 0 0 2 2 2 1 Mitochondrial domain of unknown function (DUF1713) PhyH PF05721.8 EXF82325.1 - 3.1e-08 33.9 0.0 4.2e-06 26.9 0.0 3.3 2 1 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) Pet20 PF08692.5 EXF82325.1 - 0.023 14.6 0.0 0.05 13.5 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial protein Pet20 NLPC_P60 PF00877.14 EXF82325.1 - 0.045 13.5 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 NlpC/P60 family EF_assoc_1 PF08355.7 EXF82325.1 - 0.16 11.2 0.6 1.4 8.2 0.2 2.3 2 0 0 2 2 2 0 EF hand associated Macoilin PF09726.4 EXF82325.1 - 0.95 7.6 6.5 1.5 6.9 4.5 1.3 1 0 0 1 1 1 0 Transmembrane protein GNAT_acetyltr_2 PF13718.1 EXF82326.1 - 3.2e-79 264.8 0.0 5.5e-79 264.0 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EXF82326.1 - 1.1e-66 223.8 0.1 5.1e-66 221.6 0.0 2.2 3 0 0 3 3 3 1 Helicase DUF1726 PF08351.6 EXF82326.1 - 2.1e-39 133.1 0.0 5.4e-39 131.7 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EXF82326.1 - 1.5e-35 121.3 0.4 4.2e-35 119.8 0.2 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.1 EXF82326.1 - 0.014 15.5 0.0 0.043 13.9 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4448 PF14610.1 EXF82328.1 - 7.3e-39 133.2 0.0 1.2e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) K1377 PF15352.1 EXF82329.1 - 0.044 11.7 0.0 0.053 11.4 0.0 1.1 1 0 0 1 1 1 0 Susceptibility to monomelic amyotrophy PROCN PF08083.6 EXF82331.1 - 4.9e-221 733.4 8.1 8e-221 732.6 5.6 1.4 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EXF82331.1 - 3.2e-126 419.2 1.2 6.5e-126 418.2 0.9 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EXF82331.1 - 2.9e-94 312.7 1.0 6e-94 311.7 0.7 1.6 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EXF82331.1 - 2e-75 251.5 4.2 3.5e-75 250.7 2.0 2.2 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EXF82331.1 - 1e-66 222.6 0.1 2.1e-66 221.6 0.1 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.4 EXF82331.1 - 1.1e-43 147.0 0.1 2.9e-43 145.6 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.6 EXF82331.1 - 7e-42 142.0 0.4 1.6e-41 140.8 0.0 1.9 2 0 0 2 2 2 1 PROCT (NUC072) domain DUF3753 PF12575.3 EXF82331.1 - 0.079 12.7 0.0 0.25 11.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) eIF-3c_N PF05470.7 EXF82332.1 - 6.6e-177 589.2 25.0 6.6e-177 589.2 17.3 3.1 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EXF82332.1 - 3.2e-15 56.3 0.1 1.7e-14 53.9 0.0 2.4 1 0 0 1 1 1 1 PCI domain Hemerythrin PF01814.18 EXF82335.1 - 7e-13 48.8 3.2 9.7e-13 48.4 2.2 1.1 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF4246 PF14033.1 EXF82336.1 - 5.6e-162 539.8 0.1 6.5e-162 539.6 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4246) PS_Dcarbxylase PF02666.10 EXF82337.1 - 5.9e-34 117.1 0.1 4.6e-33 114.2 0.0 2.1 1 1 0 1 1 1 1 Phosphatidylserine decarboxylase PSDC PF12588.3 EXF82337.1 - 6.3e-33 113.3 0.0 9.7e-33 112.7 0.0 1.2 1 0 0 1 1 1 1 Phophatidylserine decarboxylase RnfC_N PF13375.1 EXF82337.1 - 0.0027 17.4 0.0 2.1 8.0 0.0 3.0 3 0 0 3 3 3 2 RnfC Barrel sandwich hybrid domain HET PF06985.6 EXF82338.1 - 9.3e-39 132.7 0.0 3.3e-32 111.5 0.0 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) Lactonase PF10282.4 EXF82339.1 - 4.3e-68 229.9 0.0 5.8e-68 229.5 0.0 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller FliC_SP PF12613.3 EXF82339.1 - 0.051 13.8 1.8 0.051 13.8 1.3 3.0 3 0 0 3 3 3 0 Flagellin structural protein FAD_binding_4 PF01565.18 EXF82340.1 - 6.7e-18 64.4 0.1 6e-17 61.4 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EXF82340.1 - 4.3e-13 48.9 0.0 8.4e-13 48.0 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EXF82340.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding Glyco_hydro_43 PF04616.9 EXF82341.1 - 4.2e-107 357.4 0.5 4.2e-107 357.4 0.3 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 DUF1653 PF07866.6 EXF82342.1 - 0.039 14.1 1.6 0.071 13.3 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1653) ADH_N PF08240.7 EXF82343.1 - 3.9e-22 78.0 2.8 7.1e-22 77.2 1.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF82343.1 - 1.3e-15 57.0 0.0 2.7e-15 56.0 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF82343.1 - 0.00053 20.8 0.0 0.0012 19.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase XdhC_C PF13478.1 EXF82343.1 - 0.0044 17.3 0.0 0.011 16.0 0.0 1.7 2 0 0 2 2 2 1 XdhC Rossmann domain 2-Hacid_dh_C PF02826.14 EXF82343.1 - 0.013 14.6 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EXF82343.1 - 0.038 14.0 0.0 0.12 12.4 0.0 1.9 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase 2OG-FeII_Oxy PF03171.15 EXF82344.1 - 3.5e-21 75.3 0.0 2e-20 72.9 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EXF82344.1 - 7.8e-18 65.1 0.0 1.2e-17 64.4 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Transp_cyt_pur PF02133.10 EXF82345.1 - 1.1e-59 202.1 18.5 1.3e-59 201.9 12.8 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DUF1459 PF07312.6 EXF82345.1 - 0.12 12.2 1.4 4.7 7.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1459) DUF1768 PF08719.6 EXF82348.1 - 4.2e-45 153.3 0.2 4.9e-45 153.0 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) NAD_binding_1 PF00175.16 EXF82349.1 - 3.5e-30 104.7 0.0 5.8e-30 104.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EXF82349.1 - 1.1e-26 92.7 0.0 2e-26 91.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Cyt-b5 PF00173.23 EXF82349.1 - 1.8e-26 91.7 0.5 3.5e-26 90.7 0.2 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.7 EXF82349.1 - 2.3e-05 24.3 0.0 0.0016 18.3 0.0 2.2 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EXF82349.1 - 0.00099 19.0 0.0 0.0024 17.7 0.0 1.7 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain Vault PF01505.13 EXF82349.1 - 0.05 13.6 0.0 11 6.2 0.0 2.5 2 0 0 2 2 2 0 Major Vault Protein repeat p450 PF00067.17 EXF82350.1 - 1.3e-69 234.8 0.0 1.6e-69 234.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EXF82351.1 - 3.8e-21 75.7 0.1 5.8e-21 75.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF82351.1 - 4.7e-11 42.9 0.1 4.8e-09 36.3 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF82351.1 - 4.4e-09 36.2 0.1 7.5e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EXF82351.1 - 0.0066 15.3 0.0 0.0094 14.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EXF82351.1 - 0.039 14.0 2.1 0.05 13.7 0.4 2.0 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HemX PF04375.9 EXF82351.1 - 0.095 11.2 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 HemX adh_short PF00106.20 EXF82352.1 - 4e-18 65.9 0.3 7.3e-18 65.0 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF82352.1 - 8.9e-06 25.4 0.2 1.6e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF82352.1 - 2.9e-05 23.9 0.1 5e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EXF82352.1 - 0.0016 18.5 0.1 0.0068 16.4 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EXF82352.1 - 0.0019 17.6 0.1 0.0032 16.9 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF2678 PF10856.3 EXF82353.1 - 0.08 12.6 8.4 0.22 11.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2678) DUF996 PF06195.8 EXF82353.1 - 0.11 12.4 2.2 9.3 6.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF996) LCM PF04072.9 EXF82354.1 - 2.9e-35 121.4 0.0 3.6e-35 121.1 0.0 1.1 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase UbiA PF01040.13 EXF82355.1 - 1.3e-27 96.6 11.3 2.1e-27 95.9 7.9 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family ABC_tran PF00005.22 EXF82356.1 - 4.7e-36 124.0 0.0 1.6e-35 122.3 0.0 2.0 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.18 EXF82356.1 - 7e-21 74.8 9.5 7e-21 74.8 6.6 1.9 2 0 0 2 2 2 1 ABC transporter transmembrane region SMC_N PF02463.14 EXF82356.1 - 1.5e-06 27.6 0.6 0.00037 19.7 0.0 2.4 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EXF82356.1 - 3.5e-06 27.1 0.1 0.00046 20.2 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EXF82356.1 - 0.00046 20.3 0.3 0.0032 17.6 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EXF82356.1 - 0.00082 18.8 0.3 0.0021 17.5 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EXF82356.1 - 0.012 15.4 0.5 0.11 12.4 0.3 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EXF82356.1 - 0.02 14.3 0.9 0.064 12.6 0.1 2.0 1 1 1 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EXF82356.1 - 0.04 13.3 0.1 0.079 12.4 0.1 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF258 PF03193.11 EXF82356.1 - 0.045 12.9 0.0 0.12 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_15 PF13175.1 EXF82356.1 - 0.084 11.9 0.1 0.29 10.1 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_17 PF13207.1 EXF82356.1 - 0.13 13.1 0.0 0.27 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.12 EXF82356.1 - 0.13 12.0 0.5 0.27 11.0 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF87 AAA_16 PF13191.1 EXF82356.1 - 0.21 11.5 1.3 0.63 9.9 0.9 1.8 1 1 0 1 1 1 0 AAA ATPase domain TctB PF07331.6 EXF82358.1 - 0.025 14.2 0.2 0.025 14.2 0.1 1.9 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family HemY_N PF07219.8 EXF82358.1 - 1.8 8.1 6.8 0.11 12.0 0.4 2.2 2 2 0 2 2 2 0 HemY protein N-terminus Alpha-amylase PF00128.19 EXF82360.1 - 3.5e-27 95.6 5.6 1e-26 94.1 3.9 1.6 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EXF82360.1 - 6.5e-05 20.9 1.4 0.024 12.4 0.0 3.1 2 1 1 3 3 3 2 Glycosyl hydrolase family 70 DUF1939 PF09154.5 EXF82360.1 - 0.1 12.4 0.0 0.3 11.0 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1939) DUF647 PF04884.9 EXF82361.1 - 2e-87 292.5 0.1 2.6e-87 292.1 0.1 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis AMP-binding PF00501.23 EXF82362.1 - 5.4e-92 308.3 0.0 4.7e-90 301.9 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme ECH PF00378.15 EXF82363.1 - 2.4e-65 220.0 0.4 2.8e-65 219.8 0.3 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EXF82363.1 - 0.032 14.3 0.0 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 2-enoyl-CoA Hydratase C-terminal region SDH_sah PF01972.11 EXF82363.1 - 0.037 12.7 0.1 0.089 11.5 0.0 1.4 1 1 0 1 1 1 0 Serine dehydrogenase proteinase DUF4449 PF14613.1 EXF82364.1 - 0.00026 20.9 0.1 0.0013 18.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) Pox_C4_C10 PF03336.8 EXF82364.1 - 0.026 13.3 0.1 0.049 12.4 0.1 1.3 1 0 0 1 1 1 0 Poxvirus C4/C10 protein Senescence PF06911.7 EXF82364.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Senescence-associated protein Ank_2 PF12796.2 EXF82365.1 - 1e-108 355.8 11.3 1.6e-15 57.2 0.1 20.1 6 4 15 21 21 21 20 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EXF82365.1 - 8.2e-82 268.2 32.6 4.2e-07 30.2 0.0 28.5 17 7 12 29 29 29 16 Ankyrin repeats (many copies) Ank PF00023.25 EXF82365.1 - 2.2e-79 257.5 44.3 2.6e-06 26.9 0.0 28.8 30 2 0 30 30 30 16 Ankyrin repeat Ank_3 PF13606.1 EXF82365.1 - 4.8e-64 205.8 26.7 6.3e-05 22.8 0.0 28.6 30 1 0 30 30 29 13 Ankyrin repeat Ank_5 PF13857.1 EXF82365.1 - 1.6e-59 196.5 45.5 2.2e-05 24.5 0.1 23.0 16 8 8 24 24 24 17 Ankyrin repeats (many copies) NACHT PF05729.7 EXF82365.1 - 7.1e-09 35.5 0.0 2.6e-08 33.6 0.0 2.0 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EXF82365.1 - 0.00077 19.4 0.0 0.0031 17.5 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.4 EXF82365.1 - 0.0063 15.5 0.0 0.01 14.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Arch_ATPase PF01637.13 EXF82365.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase AAA_14 PF13173.1 EXF82365.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EXF82365.1 - 0.14 11.0 0.0 0.29 9.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.17 EXF82365.1 - 0.17 12.0 0.0 0.48 10.6 0.0 1.8 1 0 0 1 1 1 0 RNA helicase Sugar_tr PF00083.19 EXF82366.1 - 1.5e-68 231.4 18.0 7.6e-54 182.9 3.9 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EXF82366.1 - 4.2e-20 71.7 24.4 2.4e-18 65.9 8.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2236 PF09995.4 EXF82367.1 - 3.6e-11 42.8 0.0 7.1e-11 41.8 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2236) Aminotran_1_2 PF00155.16 EXF82368.1 - 8.5e-71 238.7 0.0 9.8e-71 238.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II NACHT PF05729.7 EXF82370.1 - 6.6e-07 29.1 0.1 1.1e-05 25.1 0.1 2.5 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EXF82370.1 - 4.1e-05 23.6 0.2 0.00047 20.1 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EXF82370.1 - 0.0004 20.5 0.0 0.0025 17.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_10 PF12846.2 EXF82370.1 - 0.0007 19.1 1.3 0.0017 17.8 0.1 2.3 3 0 0 3 3 3 1 AAA-like domain ABC_tran PF00005.22 EXF82370.1 - 0.00087 19.5 1.4 0.25 11.6 0.0 2.8 2 0 0 2 2 2 1 ABC transporter AAA_17 PF13207.1 EXF82370.1 - 0.0055 17.5 0.0 0.024 15.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EXF82370.1 - 0.027 14.6 0.0 0.061 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_29 PF13555.1 EXF82370.1 - 0.029 13.9 0.4 0.075 12.5 0.3 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EXF82370.1 - 0.03 14.6 0.0 0.32 11.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain Ank PF00023.25 EXF82370.1 - 0.076 12.8 0.0 18 5.3 0.0 4.2 6 0 0 6 6 6 0 Ankyrin repeat AAA_23 PF13476.1 EXF82370.1 - 0.11 12.7 0.8 0.29 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain Cut8_M PF14483.1 EXF82370.1 - 4.4 7.1 5.9 22 4.9 0.1 3.4 4 0 0 4 4 4 0 Cut8 dimerisation domain adh_short PF00106.20 EXF82371.1 - 2.7e-12 46.8 0.0 4.7e-12 46.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF82371.1 - 6.1e-05 22.8 0.0 9.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF82371.1 - 0.0002 21.0 0.0 0.00031 20.4 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EXF82371.1 - 0.0004 20.4 0.0 0.00088 19.3 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Fumble PF03630.9 EXF82371.1 - 0.098 11.4 0.0 0.14 10.9 0.0 1.1 1 0 0 1 1 1 0 Fumble Sugar_tr PF00083.19 EXF82372.1 - 2.8e-81 273.3 24.2 3.8e-81 272.9 16.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF82372.1 - 3.5e-28 98.3 24.1 3.5e-28 98.3 16.7 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EXF82372.1 - 1.6e-05 23.3 2.7 2.7e-05 22.5 1.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF4131 PF13567.1 EXF82372.1 - 0.08 12.3 8.4 4.1 6.7 0.0 3.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF1761 PF08570.5 EXF82372.1 - 0.76 9.7 12.1 0.41 10.6 4.1 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1761) MFS_1 PF07690.11 EXF82373.1 - 3.6e-27 95.0 24.6 3.6e-27 95.0 17.0 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 EXF82374.1 - 1.5e-23 82.9 0.4 2.1e-23 82.5 0.3 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain HpcH_HpaI PF03328.9 EXF82375.1 - 1.7e-34 118.6 0.0 2.1e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP-utilizers_C PF02896.13 EXF82375.1 - 6.6e-05 21.9 0.6 0.0011 17.9 0.3 2.6 2 1 0 2 2 2 1 PEP-utilising enzyme, TIM barrel domain 2-Hacid_dh_C PF02826.14 EXF82376.1 - 1.3e-46 157.9 0.0 1.9e-46 157.4 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EXF82376.1 - 4.2e-23 81.2 0.0 5e-23 81.0 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain AdoHcyase_NAD PF00670.16 EXF82376.1 - 0.00014 21.7 0.0 0.00027 20.8 0.0 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_2 PF03446.10 EXF82376.1 - 0.05 13.4 0.0 0.089 12.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase SGL PF08450.7 EXF82377.1 - 7.9e-32 110.5 0.0 4.4e-25 88.4 0.0 2.2 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Fungal_trans PF04082.13 EXF82377.1 - 1.4e-15 56.8 1.9 2.1e-15 56.2 1.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain NHL PF01436.16 EXF82377.1 - 4e-10 39.1 0.3 0.8 9.7 0.1 5.9 6 0 0 6 6 6 2 NHL repeat Str_synth PF03088.11 EXF82377.1 - 3.3e-06 27.0 0.0 0.0008 19.3 0.0 3.4 2 1 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.15 EXF82377.1 - 0.0059 16.5 0.0 0.026 14.5 0.0 2.1 2 0 0 2 2 2 1 Arylesterase Lactonase PF10282.4 EXF82377.1 - 0.081 11.9 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller Toxin_54 PF15533.1 EXF82377.1 - 0.19 11.9 1.4 0.45 10.7 0.1 2.1 2 0 0 2 2 2 0 Putative toxin 54 Sugar_tr PF00083.19 EXF82378.1 - 9.8e-38 129.8 22.8 8.9e-26 90.4 6.0 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EXF82378.1 - 1.5e-05 23.9 24.1 0.00022 20.0 1.5 2.4 2 1 0 2 2 2 2 Major Facilitator Superfamily GST_C_3 PF14497.1 EXF82379.1 - 1.3e-11 44.7 0.0 2.1e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EXF82379.1 - 5.7e-08 32.6 0.0 9e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EXF82379.1 - 0.00027 20.7 0.0 0.00063 19.5 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EXF82379.1 - 0.0007 19.7 0.0 0.01 15.9 0.0 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain PBP1_TM PF14812.1 EXF82381.1 - 2.8 8.2 8.4 2.5 8.4 1.0 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mannitol_dh_C PF08125.8 EXF82382.1 - 1.9e-73 246.6 0.0 2.7e-73 246.1 0.0 1.2 1 0 0 1 1 1 1 Mannitol dehydrogenase C-terminal domain Mannitol_dh PF01232.18 EXF82382.1 - 7.7e-50 168.7 0.0 1.4e-49 167.9 0.0 1.5 1 0 0 1 1 1 1 Mannitol dehydrogenase Rossmann domain IFT20 PF14931.1 EXF82383.1 - 0.049 13.5 0.2 3.1 7.7 0.0 2.0 2 0 0 2 2 2 0 Intraflagellar transport complex B, subunit 20 DUF632 PF04782.7 EXF82383.1 - 0.1 11.6 0.2 0.12 11.4 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF632) Baculo_PEP_C PF04513.7 EXF82384.1 - 0.013 15.3 0.2 0.07 12.9 0.0 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Fib_alpha PF08702.5 EXF82384.1 - 0.03 14.4 0.7 0.05 13.7 0.1 1.6 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family RmuC PF02646.11 EXF82384.1 - 0.073 11.9 5.3 0.027 13.3 1.6 1.8 1 1 0 1 1 1 0 RmuC family DUF2501 PF10696.4 EXF82384.1 - 0.088 12.7 1.7 0.36 10.8 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2501) Tropomyosin PF00261.15 EXF82384.1 - 0.13 11.3 5.5 0.23 10.5 3.8 1.5 1 1 0 1 1 1 0 Tropomyosin AAA_13 PF13166.1 EXF82384.1 - 0.19 10.1 5.1 0.27 9.6 3.5 1.2 1 0 0 1 1 1 0 AAA domain IFT57 PF10498.4 EXF82384.1 - 0.22 10.2 5.4 0.37 9.4 3.7 1.4 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 FAM92 PF06730.6 EXF82384.1 - 0.43 9.8 3.7 4.9 6.4 0.0 2.8 3 0 0 3 3 3 0 FAM92 protein Nsp1_C PF05064.8 EXF82384.1 - 0.46 10.1 4.0 0.18 11.4 1.1 1.7 2 0 0 2 2 2 0 Nsp1-like C-terminal region SlyX PF04102.7 EXF82384.1 - 0.79 10.1 0.0 0.79 10.1 0.0 2.9 4 0 0 4 4 4 0 SlyX DUF4094 PF13334.1 EXF82384.1 - 1.3 9.4 4.2 1.1 9.7 0.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) Tropomyosin_1 PF12718.2 EXF82384.1 - 2.2 8.1 7.5 0.3 10.9 0.1 2.4 1 1 0 2 2 2 0 Tropomyosin like CENP-F_leu_zip PF10473.4 EXF82384.1 - 4.8 7.0 8.9 2.9 7.7 1.2 2.4 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF1664 PF07889.7 EXF82385.1 - 0.011 15.4 7.8 0.083 12.6 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) COG6 PF06419.6 EXF82385.1 - 0.025 12.7 4.5 0.032 12.3 2.5 1.5 1 1 0 1 1 1 0 Conserved oligomeric complex COG6 DivIC PF04977.10 EXF82385.1 - 0.12 11.9 3.4 0.84 9.1 0.4 2.7 2 0 0 2 2 2 0 Septum formation initiator Spectrin PF00435.16 EXF82385.1 - 0.16 12.2 0.3 0.16 12.2 0.2 3.0 2 1 1 3 3 2 0 Spectrin repeat IncA PF04156.9 EXF82385.1 - 0.25 10.9 6.6 0.43 10.1 4.6 1.5 1 0 0 1 1 1 0 IncA protein GvpK PF05121.7 EXF82385.1 - 0.58 10.0 3.3 0.43 10.4 0.3 2.1 2 0 0 2 2 2 0 Gas vesicle protein K DUF3573 PF12097.3 EXF82385.1 - 0.67 8.5 2.2 1.4 7.5 0.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) T2SM PF04612.7 EXF82385.1 - 0.74 9.5 5.4 0.65 9.7 0.9 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M Fib_alpha PF08702.5 EXF82385.1 - 0.76 9.8 10.7 0.15 12.1 2.1 2.5 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF641 PF04859.7 EXF82385.1 - 0.85 9.3 7.6 0.23 11.1 1.5 2.4 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Prefoldin_2 PF01920.15 EXF82385.1 - 0.87 9.3 10.5 3.1 7.6 0.7 2.9 2 1 1 3 3 3 0 Prefoldin subunit TMF_DNA_bd PF12329.3 EXF82385.1 - 1.8 8.4 9.1 0.11 12.3 0.7 2.8 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding FlgN PF05130.7 EXF82385.1 - 3.4 7.8 11.8 2.9 8.1 2.2 2.7 1 1 1 2 2 2 0 FlgN protein DUF4446 PF14584.1 EXF82385.1 - 5.1 6.9 13.2 3.9 7.2 0.9 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) SlyX PF04102.7 EXF82385.1 - 8.4 6.8 8.9 14 6.1 1.6 3.0 1 1 1 2 2 2 0 SlyX FRQ PF09421.5 EXF82386.1 - 0.0083 13.9 0.0 0.013 13.3 0.0 1.2 1 0 0 1 1 1 1 Frequency clock protein DUF1840 PF08895.6 EXF82386.1 - 0.025 14.5 0.4 0.025 14.5 0.3 2.4 1 1 2 3 3 3 0 Domain of unknown function (DUF1840) DUF883 PF05957.8 EXF82386.1 - 4.4 7.7 7.7 8 6.9 0.5 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) MPP6 PF10175.4 EXF82386.1 - 8.9 6.7 8.2 0.9 9.9 0.4 2.4 1 1 1 2 2 2 0 M-phase phosphoprotein 6 DUF2939 PF11159.3 EXF82387.1 - 0.16 12.1 5.5 22 5.2 0.0 4.4 3 2 1 4 4 4 0 Protein of unknown function (DUF2939) Tannase PF07519.6 EXF82388.1 - 1.8e-11 43.4 0.0 2.2e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 Tannase and feruloyl esterase Zn_clus PF00172.13 EXF82389.1 - 5.4e-07 29.4 9.7 1e-06 28.5 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.8 EXF82390.1 - 2.1e-62 210.4 1.2 2.8e-62 210.0 0.8 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF82390.1 - 2.1e-17 63.7 0.2 2.9e-17 63.2 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EXF82390.1 - 2.8e-07 29.5 0.3 3.9e-07 29.0 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RTC PF01137.16 EXF82390.1 - 0.0044 15.8 0.1 0.0061 15.3 0.1 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase TrkA_N PF02254.13 EXF82390.1 - 0.014 15.3 0.1 0.047 13.7 0.0 1.8 2 0 0 2 2 2 0 TrkA-N domain NmrA PF05368.8 EXF82391.1 - 4.5e-32 111.1 0.0 5.5e-32 110.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF82391.1 - 6.1e-10 39.3 0.0 9.8e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EXF82391.1 - 3.8e-05 23.6 0.5 0.00018 21.4 0.1 2.1 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EXF82391.1 - 0.00016 21.4 0.0 0.0003 20.5 0.0 1.4 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EXF82391.1 - 0.00025 19.8 0.1 0.00094 17.9 0.1 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EXF82391.1 - 0.0036 16.7 0.0 0.022 14.2 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EXF82391.1 - 0.066 12.1 0.0 0.18 10.7 0.0 1.7 2 0 0 2 2 2 0 Male sterility protein DapB_N PF01113.15 EXF82391.1 - 0.075 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus FAD_binding_3 PF01494.14 EXF82392.1 - 2.3e-17 63.0 2.4 3.8e-07 29.4 0.0 3.1 3 0 0 3 3 3 3 FAD binding domain DAO PF01266.19 EXF82392.1 - 1.7e-08 33.7 7.6 4e-06 25.9 0.2 2.5 2 1 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF82392.1 - 1.8e-06 28.0 0.3 3.9e-05 23.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF82392.1 - 6e-06 26.1 0.1 1.6e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EXF82392.1 - 9.8e-06 24.6 0.0 1.7e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain UDPG_MGDP_dh_N PF03721.9 EXF82392.1 - 0.0025 17.2 0.6 0.13 11.6 0.0 2.2 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HI0933_like PF03486.9 EXF82392.1 - 0.0036 15.8 0.2 0.007 14.8 0.0 1.5 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.16 EXF82392.1 - 0.0067 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.5 EXF82392.1 - 0.0079 15.0 0.0 0.043 12.6 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox PF00070.22 EXF82392.1 - 0.0084 16.4 0.6 0.025 15.0 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF82392.1 - 0.012 14.5 0.1 0.018 13.8 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EXF82392.1 - 0.012 14.2 1.2 0.18 10.4 0.1 2.4 2 0 0 2 2 2 0 Tryptophan halogenase TrkA_N PF02254.13 EXF82392.1 - 0.014 15.3 0.9 0.053 13.5 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain DSBA PF01323.15 EXF82392.1 - 0.037 13.5 0.0 0.072 12.6 0.0 1.4 1 0 0 1 1 1 0 DSBA-like thioredoxin domain Pyr_redox_3 PF13738.1 EXF82392.1 - 0.039 13.9 0.2 0.16 12.0 0.1 2.1 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EXF82392.1 - 0.056 13.6 0.0 0.61 10.3 0.0 2.4 1 1 0 1 1 1 0 Putative NAD(P)-binding Lycopene_cycl PF05834.7 EXF82392.1 - 0.094 11.6 0.3 0.95 8.3 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_Gly3P_dh_N PF01210.18 EXF82392.1 - 0.13 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_9 PF13454.1 EXF82392.1 - 0.33 10.6 3.4 1.3 8.7 0.0 3.2 4 0 0 4 4 4 0 FAD-NAD(P)-binding adh_short PF00106.20 EXF82394.1 - 3.4e-19 69.3 3.0 5.1e-18 65.5 2.1 2.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF82394.1 - 1.2e-06 28.3 0.2 7.3e-06 25.7 0.0 2.0 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EXF82394.1 - 3.7e-05 23.6 0.0 0.00015 21.5 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EXF82394.1 - 0.012 14.4 0.0 0.018 13.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EXF82394.1 - 0.027 14.4 0.3 0.3 11.0 0.1 2.3 2 2 0 2 2 2 0 NADH(P)-binding Epimerase PF01370.16 EXF82394.1 - 0.043 13.2 0.0 0.17 11.2 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EXF82394.1 - 0.047 13.4 0.6 0.14 11.9 0.1 2.0 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase RmlD_sub_bind PF04321.12 EXF82394.1 - 0.13 11.1 0.0 0.23 10.3 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DUF4449 PF14613.1 EXF82395.1 - 7.6e-69 230.8 2.7 7.6e-69 230.8 1.9 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) YlqD PF11068.3 EXF82395.1 - 0.0025 17.8 1.2 0.0025 17.8 0.8 2.3 2 0 0 2 2 2 1 YlqD protein Prp18 PF02840.10 EXF82395.1 - 0.14 12.0 6.9 0.67 9.7 0.0 3.1 2 1 1 3 3 3 0 Prp18 domain SseC PF04888.7 EXF82395.1 - 0.15 11.3 11.5 0.048 13.0 1.9 2.6 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family APH PF01636.18 EXF82396.1 - 7.5e-08 32.3 0.0 7.9e-07 29.0 0.0 2.2 1 1 0 1 1 1 1 Phosphotransferase enzyme family Clr5 PF14420.1 EXF82397.1 - 2.7e-05 23.9 1.0 4.5e-05 23.2 0.0 1.9 2 0 0 2 2 2 1 Clr5 domain DUF4337 PF14235.1 EXF82397.1 - 0.058 13.2 0.9 0.15 11.8 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Herpes_US12 PF05363.7 EXF82397.1 - 0.17 12.4 3.7 0.14 12.6 0.8 2.2 2 0 0 2 2 2 0 Herpesvirus US12 family Spo7_2_N PF15407.1 EXF82398.1 - 0.084 12.3 0.0 0.23 10.9 0.0 1.7 1 0 0 1 1 1 0 Sporulation protein family 7 Peptidase_M14 PF00246.19 EXF82399.1 - 2e-19 70.2 0.0 3e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Zinc carboxypeptidase DUF2817 PF10994.3 EXF82399.1 - 0.096 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2817) MFS_1 PF07690.11 EXF82400.1 - 2.8e-17 62.4 41.3 5.3e-11 41.8 16.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CBM_1 PF00734.13 EXF82400.1 - 0.088 12.4 0.6 0.18 11.4 0.4 1.5 1 0 0 1 1 1 0 Fungal cellulose binding domain IU_nuc_hydro PF01156.14 EXF82401.1 - 1.3e-25 90.2 0.0 1.6e-25 89.9 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase VSP PF03302.8 EXF82402.1 - 0.0094 14.6 0.3 0.013 14.1 0.2 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF456 PF04306.8 EXF82402.1 - 0.046 13.7 0.1 0.076 13.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Gly-zipper_OmpA PF13436.1 EXF82402.1 - 0.088 12.4 2.8 0.14 11.8 0.5 2.1 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 EXF82402.1 - 2.6 7.6 9.9 0.73 9.4 4.1 2.1 2 0 0 2 2 2 0 YMGG-like Gly-zipper DNA_ligase_A_M PF01068.16 EXF82403.1 - 2.7e-43 147.7 0.0 5.3e-43 146.7 0.0 1.5 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EXF82403.1 - 5.4e-36 124.0 0.0 9.7e-36 123.2 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EXF82403.1 - 1.2e-16 60.8 0.0 5.3e-16 58.8 0.0 2.2 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EXF82403.1 - 4.5e-09 36.3 0.1 3.5e-06 27.0 0.0 2.9 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.3 EXF82403.1 - 0.00085 19.0 0.0 0.0017 18.0 0.0 1.5 1 0 0 1 1 1 1 DNA ligase IV mRNA_cap_enzyme PF01331.14 EXF82403.1 - 0.0028 17.3 0.2 0.28 10.8 0.0 3.0 3 1 0 3 3 3 1 mRNA capping enzyme, catalytic domain UPRTase PF14681.1 EXF82404.1 - 1.8e-74 249.4 0.0 2.1e-74 249.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EXF82404.1 - 5.7e-07 29.2 0.0 1e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain TMP-TENI PF02581.12 EXF82404.1 - 0.01 14.9 0.8 0.089 11.9 0.1 2.2 2 1 0 2 2 2 0 Thiamine monophosphate synthase/TENI Peptidase_S13 PF02113.10 EXF82404.1 - 0.095 11.1 0.0 0.12 10.9 0.0 1.1 1 0 0 1 1 1 0 D-Ala-D-Ala carboxypeptidase 3 (S13) family CRCB PF02537.10 EXF82405.1 - 2.3e-31 108.0 24.4 1.2e-19 70.3 6.7 4.1 4 0 0 4 4 4 3 CrcB-like protein Ribosomal_L13e PF01294.13 EXF82405.1 - 0.023 14.1 0.0 0.47 9.8 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L13e Pox_A30L_A26L PF06086.7 EXF82406.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Orthopoxvirus A26L/A30L protein ATPase_gene1 PF09527.5 EXF82406.1 - 1.4 8.7 13.5 0.8 9.5 0.3 4.2 4 0 0 4 4 4 0 Putative F0F1-ATPase subunit (ATPase_gene1) zf-H2C2_2 PF13465.1 EXF82407.1 - 9.5e-21 73.0 18.9 1.9e-07 31.0 0.3 4.6 4 0 0 4 4 4 3 Zinc-finger double domain zf-C2H2 PF00096.21 EXF82407.1 - 5.3e-16 57.8 23.9 0.00013 22.0 0.0 4.5 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF82407.1 - 1e-07 31.7 23.3 0.014 15.6 0.7 4.6 4 0 0 4 4 4 3 C2H2-type zinc finger zf-met PF12874.2 EXF82407.1 - 0.027 14.6 8.6 2.3 8.5 0.1 4.1 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-TRAF PF02176.13 EXF82407.1 - 0.063 13.6 0.4 0.063 13.6 0.3 3.4 2 1 1 3 3 3 0 TRAF-type zinc finger Olfactory_mark PF06554.7 EXF82407.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Olfactory marker protein IBR PF01485.16 EXF82407.1 - 6.5 6.6 12.7 7.7e+02 0.0 8.8 3.3 1 1 0 1 1 1 0 IBR domain FAD_binding_4 PF01565.18 EXF82408.1 - 5.3e-21 74.5 5.3 9e-21 73.8 3.6 1.4 1 0 0 1 1 1 1 FAD binding domain EthD PF07110.6 EXF82409.1 - 4e-13 50.1 0.1 4.8e-13 49.8 0.1 1.1 1 0 0 1 1 1 1 EthD domain peroxidase PF00141.18 EXF82410.1 - 5.7e-25 88.1 0.0 9.1e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Peroxidase DUF2312 PF10073.4 EXF82410.1 - 0.17 11.2 0.1 4.2 6.7 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) S1 PF00575.18 EXF82411.1 - 1.3e-83 275.0 47.0 1.2e-15 57.3 0.6 13.2 13 0 0 13 13 13 11 S1 RNA binding domain TPR_14 PF13428.1 EXF82411.1 - 4.8e-06 26.7 0.4 0.88 10.3 0.0 4.8 3 1 1 4 4 4 2 Tetratricopeptide repeat S1_2 PF13509.1 EXF82411.1 - 1.6e-05 24.7 0.4 4.6 7.2 0.0 4.9 4 0 0 4 4 4 2 S1 domain TPR_16 PF13432.1 EXF82411.1 - 4.3e-05 24.0 0.3 0.48 11.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EXF82411.1 - 8.1e-05 22.8 3.0 0.28 11.5 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat EXOSC1 PF10447.4 EXF82411.1 - 0.064 13.2 18.8 3.1 7.8 0.0 7.8 8 3 1 10 10 10 0 Exosome component EXOSC1/CSL4 TPR_6 PF13174.1 EXF82411.1 - 0.19 12.2 0.2 11 6.7 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M16_C PF05193.16 EXF82413.1 - 5.4e-54 182.6 0.0 1.5e-53 181.1 0.0 1.7 1 1 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EXF82413.1 - 9.5e-40 135.7 0.0 6.1e-39 133.1 0.0 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Disulph_isomer PF06491.6 EXF82413.1 - 0.075 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Disulphide isomerase FAM104 PF15434.1 EXF82413.1 - 3 8.1 6.4 37 4.5 4.5 2.2 1 1 0 1 1 1 0 Family 104 FHA PF00498.21 EXF82414.1 - 1.8e-15 56.8 0.0 3.4e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EXF82414.1 - 3e-06 26.9 12.4 5.1e-06 26.2 8.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EXF82414.1 - 9.4e-06 25.6 7.7 1.9e-05 24.7 5.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EXF82414.1 - 0.011 15.3 12.8 0.019 14.6 8.9 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EXF82414.1 - 0.17 11.7 3.3 0.34 10.7 2.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger PHD PF00628.24 EXF82414.1 - 0.29 10.8 7.9 0.56 9.9 5.5 1.5 1 0 0 1 1 1 0 PHD-finger zf-RING_5 PF14634.1 EXF82414.1 - 0.46 10.2 10.5 0.77 9.5 7.3 1.4 1 0 0 1 1 1 0 zinc-RING finger domain lci PF12197.3 EXF82414.1 - 0.63 9.6 2.4 0.62 9.6 0.5 1.8 2 0 0 2 2 2 0 Bacillus cereus group antimicrobial protein zf-C3HC4_2 PF13923.1 EXF82414.1 - 2.8 8.0 14.2 4.8 7.2 9.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vps16_N PF04841.8 EXF82415.1 - 8.8e-84 281.4 0.0 1.5e-83 280.5 0.0 1.4 1 1 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.7 EXF82415.1 - 8.8e-78 261.4 0.0 1.3e-77 260.8 0.0 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region ATG16 PF08614.6 EXF82416.1 - 2e-42 145.2 25.0 2.3e-42 145.0 17.3 1.0 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) bZIP_1 PF00170.16 EXF82416.1 - 0.0013 18.6 15.3 0.11 12.4 0.0 4.3 3 1 2 5 5 5 2 bZIP transcription factor CCDC144C PF14915.1 EXF82416.1 - 0.0027 16.6 23.7 0.056 12.3 10.7 2.1 1 1 1 2 2 2 2 CCDC144C protein coiled-coil region Filament PF00038.16 EXF82416.1 - 0.0038 16.7 18.4 0.077 12.4 5.0 2.6 1 1 1 2 2 2 2 Intermediate filament protein TSC22 PF01166.13 EXF82416.1 - 0.068 13.1 10.1 0.33 10.9 0.1 4.2 2 1 3 5 5 5 0 TSC-22/dip/bun family Wzz PF02706.10 EXF82416.1 - 0.097 12.4 8.5 0.22 11.3 5.9 1.6 1 1 0 1 1 1 0 Chain length determinant protein SurA_N PF09312.6 EXF82416.1 - 0.18 11.6 7.8 0.062 13.1 2.6 2.2 1 1 1 2 2 2 0 SurA N-terminal domain Kinesin-relat_1 PF12711.2 EXF82416.1 - 0.3 11.5 14.4 0.88 10.0 6.6 3.1 2 1 1 3 3 3 0 Kinesin motor FlxA PF14282.1 EXF82416.1 - 0.36 10.8 22.0 1.6 8.7 4.1 3.1 1 1 2 3 3 3 0 FlxA-like protein KIAA1430 PF13879.1 EXF82416.1 - 0.82 10.1 18.2 0.54 10.6 6.3 2.3 1 1 1 2 2 2 0 KIAA1430 homologue LAGLIDADG_WhiA PF14527.1 EXF82416.1 - 0.97 9.3 3.4 0.83 9.5 0.9 1.9 2 0 0 2 2 2 0 WhiA LAGLIDADG-like domain Prominin PF05478.6 EXF82416.1 - 3.6 5.0 9.6 4.4 4.7 6.7 1.2 1 0 0 1 1 1 0 Prominin IncA PF04156.9 EXF82416.1 - 4.4 6.8 19.5 46 3.5 13.5 2.3 1 1 0 1 1 1 0 IncA protein DivIVA PF05103.8 EXF82416.1 - 4.9 7.2 21.2 3.1 7.8 6.0 2.4 1 1 1 2 2 2 0 DivIVA protein DUF972 PF06156.8 EXF82416.1 - 8.2 6.8 20.9 18 5.7 0.5 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DOT1 PF08123.8 EXF82417.1 - 6.2e-72 241.2 0.0 9e-72 240.6 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 EXF82417.1 - 0.00083 19.3 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF82417.1 - 0.001 18.6 0.0 0.0042 16.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF82417.1 - 0.11 13.0 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Nucleo_P87 PF07267.6 EXF82417.1 - 0.18 10.4 3.8 0.29 9.7 2.7 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 F-box PF00646.28 EXF82418.1 - 0.0017 17.9 0.0 0.0043 16.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EXF82418.1 - 0.044 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 F-box-like F-box-like PF12937.2 EXF82419.1 - 0.018 14.7 0.1 0.048 13.4 0.1 1.7 1 0 0 1 1 1 0 F-box-like Ceramidase PF05875.7 EXF82420.1 - 7.7e-51 172.7 5.0 9.3e-51 172.4 3.5 1.0 1 0 0 1 1 1 1 Ceramidase Leader_Trp PF08255.6 EXF82420.1 - 0.083 12.5 3.2 0.43 10.3 2.2 2.2 1 0 0 1 1 1 0 Trp-operon Leader Peptide DUF2306 PF10067.4 EXF82420.1 - 0.089 12.9 5.2 0.078 13.1 1.4 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2306) SID-1_RNA_chan PF13965.1 EXF82420.1 - 0.45 8.6 2.8 0.79 7.8 2.0 1.4 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 Glyco_tranf_2_3 PF13641.1 EXF82421.1 - 9.1e-19 68.1 0.3 1.3e-18 67.6 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EXF82421.1 - 2.5e-09 36.6 0.3 5.9e-09 35.4 0.2 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EXF82421.1 - 2.8e-08 33.6 0.0 4.5e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Sugar_tr PF00083.19 EXF82423.1 - 6.7e-69 232.6 19.4 9.8e-53 179.3 4.0 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter TPR_19 PF14559.1 EXF82423.1 - 0.11 12.9 0.1 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Mpv17_PMP22 PF04117.7 EXF82425.1 - 2.3e-14 52.7 7.7 2.9e-14 52.4 3.9 2.0 1 1 1 2 2 2 1 Mpv17 / PMP22 family DUF1593 PF07632.6 EXF82426.1 - 9e-101 336.5 0.0 1.1e-100 336.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) GST_C PF00043.20 EXF82427.1 - 2.5e-08 33.7 0.0 3.1e-08 33.4 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EXF82427.1 - 2.6e-06 27.1 0.1 3.4e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EXF82427.1 - 0.043 14.3 0.1 0.06 13.8 0.0 1.3 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EXF82428.1 - 1.2e-13 51.0 0.0 1.6e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EXF82428.1 - 7.2e-10 38.9 0.0 9.3e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EXF82428.1 - 2.9e-09 36.7 0.0 3.8e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain FTO_NTD PF12933.2 EXF82428.1 - 0.0015 17.7 0.0 0.0016 17.6 0.0 1.1 1 0 0 1 1 1 1 FTO catalytic domain AA_permease_C PF13906.1 EXF82429.1 - 0.072 12.9 2.8 0.26 11.1 0.3 2.7 2 0 0 2 2 2 0 C-terminus of AA_permease DJ-1_PfpI PF01965.19 EXF82429.1 - 0.15 11.4 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family FAD_binding_4 PF01565.18 EXF82430.1 - 3.7e-23 81.5 0.4 6.2e-23 80.8 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF82430.1 - 3.2 7.7 6.0 1.8 8.5 0.0 3.3 4 0 0 4 4 4 0 Berberine and berberine like Fungal_trans PF04082.13 EXF82431.1 - 4.1e-15 55.3 0.1 6.1e-15 54.7 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_5 PF12695.2 EXF82432.1 - 1.2e-10 41.3 0.1 2.1e-09 37.2 0.1 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF82432.1 - 1.2e-10 41.6 0.1 1.6e-10 41.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EXF82432.1 - 1.7e-07 30.7 0.0 4.3e-06 26.1 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EXF82432.1 - 0.00096 18.4 0.0 0.018 14.2 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family AXE1 PF05448.7 EXF82432.1 - 0.015 13.8 0.1 0.032 12.7 0.0 1.5 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Ectoine_synth PF06339.7 EXF82433.1 - 0.0071 16.2 0.1 0.0094 15.8 0.1 1.1 1 0 0 1 1 1 1 Ectoine synthase p450 PF00067.17 EXF82434.1 - 1.8e-32 112.4 0.0 2.4e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 MinE PF03776.9 EXF82434.1 - 0.089 12.3 0.0 0.26 10.8 0.0 1.7 1 0 0 1 1 1 0 Septum formation topological specificity factor MinE p450 PF00067.17 EXF82435.1 - 7.4e-61 206.0 0.0 9.4e-61 205.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyoxalase_2 PF12681.2 EXF82436.1 - 2e-05 25.1 0.3 0.11 13.0 0.1 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain Glyoxalase PF00903.20 EXF82436.1 - 2.2e-05 24.4 1.8 0.00023 21.1 0.8 2.6 3 0 0 3 3 3 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily FAA_hydrolase PF01557.13 EXF82437.1 - 1.2e-50 171.9 0.0 1.4e-50 171.7 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Tnp_P_element_C PF12596.3 EXF82437.1 - 0.046 14.0 0.1 0.074 13.3 0.1 1.3 1 0 0 1 1 1 0 87kDa Transposase Beta-lactamase PF00144.19 EXF82438.1 - 1e-38 133.2 0.9 1.4e-38 132.7 0.7 1.1 1 0 0 1 1 1 1 Beta-lactamase Fungal_trans PF04082.13 EXF82439.1 - 1.5e-10 40.3 0.7 3.9e-10 39.0 0.5 1.8 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF82439.1 - 2.1e-08 33.9 11.3 2.1e-08 33.9 7.8 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AA_permease_2 PF13520.1 EXF82440.1 - 4.2e-38 130.9 42.4 5.3e-38 130.6 29.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF82440.1 - 1e-20 73.5 38.8 1.6e-20 72.8 26.9 1.2 1 0 0 1 1 1 1 Amino acid permease FAD_binding_3 PF01494.14 EXF82441.1 - 5e-22 78.4 1.8 2.8e-15 56.2 0.1 2.9 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EXF82441.1 - 2.3e-09 36.6 0.4 2.2e-05 23.5 0.2 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF82441.1 - 3.1e-07 30.4 0.4 2.2e-06 27.6 0.3 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF82441.1 - 4.3e-07 28.7 0.2 0.0017 16.8 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 EXF82441.1 - 5.5e-07 28.7 0.1 9e-07 28.0 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EXF82441.1 - 8.9e-06 26.0 1.8 0.0074 16.6 0.7 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF82441.1 - 8.6e-05 22.4 0.1 0.00022 21.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EXF82441.1 - 0.0003 19.9 1.8 0.00043 19.4 0.2 1.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.17 EXF82441.1 - 0.00036 19.5 0.1 0.0009 18.2 0.0 1.6 2 0 0 2 2 2 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EXF82441.1 - 0.00084 19.4 0.1 0.76 9.8 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF82441.1 - 0.0018 17.3 0.1 0.0032 16.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.7 EXF82441.1 - 0.02 13.8 0.3 1.3 7.9 0.1 2.8 3 0 0 3 3 3 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EXF82441.1 - 0.12 10.9 1.3 0.94 8.0 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Cys_Met_Meta_PP PF01053.15 EXF82442.1 - 2.1e-121 404.8 0.0 2.4e-121 404.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EXF82442.1 - 2.8e-12 46.3 0.6 5.9e-12 45.2 0.4 1.4 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.16 EXF82442.1 - 3.6e-07 29.6 0.0 6.2e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EXF82442.1 - 2.2e-05 23.3 0.1 3.4e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EXF82442.1 - 0.0096 14.9 0.0 0.015 14.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II SLA_LP_auto_ag PF05889.8 EXF82442.1 - 0.14 10.5 0.0 0.22 9.9 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) adh_short PF00106.20 EXF82443.1 - 4.5e-26 91.7 0.2 9.2e-26 90.7 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF82443.1 - 1.9e-23 83.4 0.0 2.8e-23 82.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF82443.1 - 1.9e-10 40.6 0.1 2.4e-09 37.1 0.1 2.0 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 EXF82443.1 - 0.01 14.9 0.0 0.44 9.6 0.0 2.4 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DAO PF01266.19 EXF82444.1 - 2.8e-40 138.3 0.0 1.3e-38 132.8 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EXF82444.1 - 3.1e-22 79.2 0.3 1.2e-12 47.6 0.0 2.7 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EXF82444.1 - 4.3e-13 49.0 0.2 1.9e-05 24.5 0.0 2.7 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EXF82444.1 - 1.3e-08 35.1 0.0 0.084 12.9 0.0 3.4 2 1 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EXF82444.1 - 6.1e-06 25.5 0.0 0.028 13.4 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 EXF82444.1 - 2.5e-05 24.5 0.1 0.012 15.9 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF82444.1 - 0.00016 21.5 0.0 0.0068 16.3 0.0 3.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF82444.1 - 0.0039 16.9 0.5 0.1 12.3 0.0 3.0 3 0 0 3 3 3 1 FAD-NAD(P)-binding Thi4 PF01946.12 EXF82444.1 - 0.0092 15.1 0.2 0.22 10.5 0.0 2.2 2 0 0 2 2 2 1 Thi4 family 2-Hacid_dh_C PF02826.14 EXF82444.1 - 0.024 13.7 0.0 0.074 12.2 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ARL2_Bind_BART PF11527.3 EXF82444.1 - 0.029 14.1 0.0 0.064 13.0 0.0 1.5 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART 3HCDH_N PF02737.13 EXF82444.1 - 0.035 13.7 0.0 0.072 12.7 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EXF82444.1 - 0.036 13.9 0.0 0.095 12.5 0.0 1.7 2 0 0 2 2 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 EXF82444.1 - 0.091 12.1 0.1 0.56 9.6 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EXF82444.1 - 0.093 12.4 0.1 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EXF82444.1 - 0.099 12.0 0.2 0.78 9.0 0.0 2.2 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.19 EXF82444.1 - 0.12 11.1 0.1 0.57 8.9 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.17 EXF82444.1 - 0.42 9.4 0.1 30 3.3 0.0 2.8 3 0 0 3 3 3 0 Glucose inhibited division protein A MFS_1 PF07690.11 EXF82445.1 - 4.9e-23 81.3 24.2 9.7e-23 80.4 15.3 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Peptidase_M50 PF02163.17 EXF82445.1 - 0.0016 17.4 1.5 0.0016 17.4 1.0 2.0 2 0 0 2 2 2 1 Peptidase family M50 Tannase PF07519.6 EXF82446.1 - 1.2e-87 294.6 0.0 1.5e-86 291.0 0.0 2.1 1 1 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_1 PF00561.15 EXF82446.1 - 0.0035 16.9 0.0 0.0085 15.6 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EXF82446.1 - 0.012 15.5 0.2 0.022 14.6 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family COG2 PF06148.6 EXF82447.1 - 2.5e-24 85.6 0.0 3.7e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 EXF82447.1 - 0.005 16.6 0.0 0.014 15.2 0.0 1.8 2 1 0 2 2 2 1 Vps51/Vps67 CENP-F_leu_zip PF10473.4 EXF82447.1 - 0.085 12.7 0.2 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CENP-B_dimeris PF09026.5 EXF82447.1 - 0.34 11.1 5.2 0.83 9.9 3.6 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nucleoplasmin PF03066.10 EXF82447.1 - 0.72 9.3 4.8 1.1 8.7 3.3 1.2 1 0 0 1 1 1 0 Nucleoplasmin DUF2457 PF10446.4 EXF82447.1 - 1.9 7.1 5.7 2.8 6.5 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.7 EXF82447.1 - 2.2 7.5 6.5 3.2 6.9 4.5 1.2 1 0 0 1 1 1 0 SDA1 S-antigen PF05756.6 EXF82447.1 - 2.8 7.9 4.6 24 4.9 4.1 1.8 2 0 0 2 2 2 0 S-antigen protein Ribosomal_L1 PF00687.16 EXF82448.1 - 1.1e-23 83.7 0.3 1.8e-23 83.0 0.2 1.4 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family tRNA-synt_1c PF00749.16 EXF82449.1 - 9.8e-100 333.2 0.1 1.3e-99 332.8 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EXF82449.1 - 8.2e-40 136.2 0.0 1.7e-39 135.3 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.14 EXF82449.1 - 0.012 14.7 0.2 0.035 13.2 0.1 1.5 1 1 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain 2-Hacid_dh_C PF02826.14 EXF82450.1 - 7.4e-37 126.2 0.0 1.1e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EXF82450.1 - 3.4e-06 26.9 0.0 5.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.25 EXF82450.1 - 0.0014 18.0 0.0 0.0031 16.9 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Semialdhyde_dh PF01118.19 EXF82450.1 - 0.036 14.3 0.0 0.4 11.0 0.0 2.3 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain HET PF06985.6 EXF82451.1 - 9.9e-07 28.9 0.0 1.6e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Sugar_tr PF00083.19 EXF82453.1 - 1.6e-105 353.3 29.3 1.8e-105 353.1 20.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF82453.1 - 6.5e-24 84.2 46.4 4.3e-19 68.4 8.2 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily Cyclase PF04199.8 EXF82454.1 - 2.4e-18 66.3 0.0 3.4e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Putative cyclase Fungal_trans PF04082.13 EXF82455.1 - 7.6e-26 90.5 0.0 1.2e-25 89.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF82455.1 - 9.6e-08 31.8 9.4 9.6e-08 31.8 6.5 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DMPK_coil PF08826.5 EXF82455.1 - 0.055 13.3 0.2 0.49 10.3 0.0 2.5 3 0 0 3 3 3 0 DMPK coiled coil domain like MFS_1 PF07690.11 EXF82456.1 - 5.5e-29 100.9 38.5 5.5e-29 100.9 26.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily TMEM51 PF15345.1 EXF82456.1 - 2.1 7.9 0.0 2.1 7.9 0.0 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 DUF2839 PF10999.3 EXF82456.1 - 5.2 7.1 6.3 8.3 6.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) CoA_transf_3 PF02515.12 EXF82457.1 - 1e-43 148.8 0.0 1.1e-41 142.2 0.0 2.4 2 1 0 2 2 2 2 CoA-transferase family III DUF4387 PF14330.1 EXF82457.1 - 3.9e-37 126.5 0.0 8.5e-37 125.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4387) DUF1446 PF07287.6 EXF82457.1 - 7.1e-22 77.3 0.0 2.1e-11 42.9 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1446) KAT11 PF08214.6 EXF82458.1 - 6.3e-96 321.4 0.0 8.5e-96 321.0 0.0 1.2 1 0 0 1 1 1 1 Histone acetylation protein HHV6-IE PF03753.8 EXF82458.1 - 0.47 7.8 1.3 0.75 7.2 0.7 1.4 2 0 0 2 2 2 0 Human herpesvirus 6 immediate early protein Ribonucleas_3_3 PF14622.1 EXF82459.1 - 4.3e-26 91.3 0.0 9e-26 90.3 0.0 1.5 1 1 0 1 1 1 1 Ribonuclease-III-like PIRT PF15099.1 EXF82461.1 - 0.0098 15.1 2.4 0.019 14.1 1.6 1.4 1 0 0 1 1 1 1 Phosphoinositide-interacting protein family DUF2939 PF11159.3 EXF82461.1 - 0.019 15.1 0.2 0.73 10.0 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2939) Peptidase_M22 PF00814.20 EXF82461.1 - 0.019 14.4 0.2 0.042 13.3 0.1 1.6 1 0 0 1 1 1 0 Glycoprotease family DUF2427 PF10348.4 EXF82461.1 - 9.6 5.8 11.3 15 5.2 2.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) K_channel_TID PF07941.6 EXF82462.1 - 0.003 17.7 5.0 0.011 15.9 3.4 2.0 1 0 0 1 1 1 1 Potassium channel Kv1.4 tandem inactivation domain WSC PF01822.14 EXF82463.1 - 1.3e-12 47.4 4.3 1.3e-12 47.4 3.0 3.7 4 2 0 4 4 4 1 WSC domain Macoilin PF09726.4 EXF82463.1 - 0.95 7.6 5.0 1.2 7.3 3.5 1.1 1 0 0 1 1 1 0 Transmembrane protein TauD PF02668.11 EXF82464.1 - 3.5e-40 138.3 0.1 4.3e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Transgly PF00912.17 EXF82464.1 - 0.15 11.3 0.1 0.3 10.3 0.1 1.4 1 0 0 1 1 1 0 Transglycosylase MFS_1 PF07690.11 EXF82465.1 - 4.6e-14 51.9 27.3 4.6e-14 51.9 18.9 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily UNC-93 PF05978.11 EXF82465.1 - 1.1e-10 41.1 4.6 1.1e-10 41.1 3.2 2.1 2 0 0 2 2 2 1 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 EXF82465.1 - 0.00034 19.3 10.1 0.00034 19.3 7.0 2.1 1 1 0 2 2 2 1 Sugar (and other) transporter Hydrophobin_2 PF06766.6 EXF82466.1 - 1.5e-25 88.6 10.4 2e-25 88.2 7.2 1.1 1 0 0 1 1 1 1 Fungal hydrophobin 7TM_GPCR_Str PF10326.4 EXF82467.1 - 5 6.1 10.7 4.2 6.4 6.6 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str p450 PF00067.17 EXF82468.1 - 3.4e-67 226.9 0.0 4.5e-67 226.5 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans_2 PF11951.3 EXF82469.1 - 7.6e-08 31.3 0.1 1.3e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3452 PF11934.3 EXF82469.1 - 0.12 11.6 0.0 0.34 10.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Sugar_tr PF00083.19 EXF82470.1 - 2.7e-102 342.6 29.7 3.2e-102 342.4 20.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF82470.1 - 7e-32 110.5 29.4 7e-32 110.5 20.4 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily Lig_chan PF00060.21 EXF82470.1 - 2.8 7.6 7.7 0.98 9.1 0.1 2.7 2 0 0 2 2 2 0 Ligand-gated ion channel Rrp15p PF07890.7 EXF82471.1 - 1.1e-35 122.5 14.0 1.1e-35 122.5 9.7 2.3 2 1 0 2 2 2 1 Rrp15p PRTP PF01366.13 EXF82471.1 - 0.51 8.2 3.7 0.87 7.5 2.5 1.3 1 0 0 1 1 1 0 Herpesvirus processing and transport protein Fer2 PF00111.22 EXF82472.1 - 4.3e-14 52.0 1.1 6.5e-14 51.4 0.7 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.22 EXF82473.1 - 4.2e-18 64.8 0.5 0.00043 19.9 0.0 5.2 4 1 0 4 4 4 4 Mitochondrial carrier protein Glyco_hydro_61 PF03443.9 EXF82474.1 - 2.3e-77 259.6 0.1 2.3e-77 259.6 0.1 2.0 2 1 0 2 2 2 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EXF82474.1 - 1.1e-17 63.2 20.0 6.8e-09 35.2 3.7 2.7 2 0 0 2 2 2 2 Fungal cellulose binding domain CSD PF00313.17 EXF82474.1 - 0.082 12.7 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain Fungal_trans_2 PF11951.3 EXF82476.1 - 7.6e-19 67.5 0.1 1e-18 67.1 0.1 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF82476.1 - 0.00032 20.5 8.5 0.00092 19.0 5.9 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_racemase PF05544.6 EXF82477.1 - 4.4e-126 420.1 0.0 5e-126 419.9 0.0 1.0 1 0 0 1 1 1 1 Proline racemase MFS_1 PF07690.11 EXF82478.1 - 9.6e-26 90.3 33.2 1.6e-25 89.5 17.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF82478.1 - 1.5e-09 36.9 23.4 8.7e-07 27.8 8.4 2.7 2 1 0 2 2 2 2 Sugar (and other) transporter TRI12 PF06609.8 EXF82478.1 - 4.4e-09 35.1 5.0 7.2e-09 34.3 3.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Corona_S2 PF01601.11 EXF82478.1 - 0.3 9.1 1.0 0.43 8.6 0.7 1.1 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein Keratin_assoc PF09775.4 EXF82478.1 - 4.2 6.9 8.0 2.6 7.6 0.4 2.7 2 1 0 2 2 2 0 Keratinocyte-associated protein 2 Helicase_C PF00271.26 EXF82479.1 - 1.2e-18 66.7 0.1 4.8e-17 61.5 0.0 2.9 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EXF82479.1 - 2e-17 63.2 0.0 5.9e-17 61.6 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase F-box-like PF12937.2 EXF82480.1 - 4.5e-06 26.2 0.0 1.7e-05 24.4 0.0 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EXF82480.1 - 6.1e-05 22.5 0.2 0.0016 18.0 0.2 2.8 1 1 0 1 1 1 1 F-box domain UBN2_2 PF14227.1 EXF82480.1 - 0.025 14.1 0.2 0.047 13.2 0.1 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Cytochrom_B562 PF07361.6 EXF82481.1 - 0.24 11.8 16.0 0.05 14.0 8.4 1.8 1 1 0 1 1 1 0 Cytochrome b562 Hid1 PF12722.2 EXF82481.1 - 6.3 4.3 11.4 6.9 4.2 7.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Glyco_hydro_43 PF04616.9 EXF82482.1 - 1.1e-58 198.6 1.3 1.4e-58 198.2 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Abhydrolase_5 PF12695.2 EXF82483.1 - 2.8e-07 30.3 0.0 4e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Oxidored_q6 PF01058.17 EXF82484.1 - 1.6e-22 79.5 0.2 2.1e-22 79.1 0.1 1.2 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Fungal_trans PF04082.13 EXF82485.1 - 9.4e-06 24.6 0.0 1.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF82485.1 - 4.6e-05 23.2 8.1 4.6e-05 23.2 5.6 2.3 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dioxygenase_C PF00775.16 EXF82486.1 - 3.7e-10 39.3 0.4 6.7e-10 38.5 0.3 1.5 1 1 0 1 1 1 1 Dioxygenase Arch_ATPase PF01637.13 EXF82487.1 - 4.7e-06 26.4 0.0 8.4e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase DUF815 PF05673.8 EXF82487.1 - 0.00058 18.8 0.0 0.0013 17.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EXF82487.1 - 0.0007 19.6 4.0 0.046 13.6 1.8 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EXF82487.1 - 0.0078 15.6 0.0 0.022 14.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EXF82487.1 - 0.03 14.7 0.2 0.7 10.4 0.2 2.4 1 1 0 1 1 1 0 Miro-like protein AAA_29 PF13555.1 EXF82487.1 - 0.036 13.5 0.1 0.079 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.1 EXF82487.1 - 0.038 14.1 0.1 0.11 12.6 0.1 1.7 1 1 0 1 1 1 0 AAA domain KaiC PF06745.8 EXF82487.1 - 0.078 12.0 1.3 0.18 10.8 0.9 1.7 1 1 0 1 1 1 0 KaiC IPP-2 PF04979.9 EXF82488.1 - 2.7e-09 37.3 18.5 8.1e-08 32.5 11.5 2.5 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) DUF2076 PF09849.4 EXF82489.1 - 0.0005 20.1 0.2 0.0005 20.1 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Ribosomal_L27 PF01016.14 EXF82490.1 - 2e-22 78.7 0.0 4.2e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Ribosomal L27 protein DUF3716 PF12511.3 EXF82491.1 - 4.5e-05 22.9 3.2 8.5e-05 22.0 2.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) Cupin_3 PF05899.7 EXF82491.1 - 0.031 13.6 0.0 0.14 11.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF861) Transp_cyt_pur PF02133.10 EXF82492.1 - 3.4e-100 335.6 40.4 4.1e-100 335.3 28.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin DIOX_N PF14226.1 EXF82493.1 - 3.8e-26 91.9 0.2 6.6e-26 91.1 0.2 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EXF82493.1 - 4.4e-23 81.4 0.0 1e-22 80.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HET PF06985.6 EXF82494.1 - 8.2e-17 61.6 0.0 2.1e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3176 PF11374.3 EXF82495.1 - 1.8e-34 117.9 1.6 1.8e-34 117.9 1.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) SET PF00856.23 EXF82497.1 - 7.8e-14 52.2 0.0 5e-13 49.6 0.0 2.1 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.6 EXF82497.1 - 6e-12 45.5 0.5 1.2e-11 44.6 0.4 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Adap_comp_sub PF00928.16 EXF82499.1 - 7e-90 300.6 0.0 9.4e-90 300.2 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EXF82499.1 - 5.7e-09 35.8 0.2 9.4e-09 35.1 0.1 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Opi1 PF08618.5 EXF82500.1 - 8.7e-81 272.0 10.0 2.1e-48 165.3 0.4 4.7 3 2 2 5 5 5 3 Transcription factor Opi1 AA_permease_N PF08403.5 EXF82500.1 - 0.016 14.4 0.7 0.05 12.9 0.5 1.8 1 0 0 1 1 1 0 Amino acid permease N-terminal Glyco_hydro_71 PF03659.9 EXF82501.1 - 6.3e-122 406.7 2.2 7.4e-122 406.5 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.1 EXF82501.1 - 0.044 13.5 0.0 0.18 11.5 0.0 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4434) AP_endonuc_2 PF01261.19 EXF82501.1 - 0.078 12.2 0.0 0.17 11.1 0.0 1.5 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel Glyco_hydro_71 PF03659.9 EXF82502.1 - 8.9e-138 458.9 1.8 1e-137 458.7 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 DUF4434 PF14488.1 EXF82502.1 - 0.067 12.9 0.1 0.2 11.3 0.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4434) GMC_oxred_N PF00732.14 EXF82504.1 - 5.4e-60 203.0 0.0 7.4e-60 202.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF82504.1 - 1.2e-27 97.0 0.0 1.9e-27 96.2 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase Lycopene_cycl PF05834.7 EXF82504.1 - 0.00011 21.2 0.0 0.00016 20.7 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EXF82504.1 - 0.00034 19.5 2.7 0.0025 16.7 1.9 2.0 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EXF82504.1 - 0.0044 15.6 0.1 0.0073 14.9 0.1 1.3 1 0 0 1 1 1 1 Tryptophan halogenase Pyr_redox_2 PF07992.9 EXF82504.1 - 0.0055 16.6 0.0 0.016 15.0 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF82504.1 - 0.0087 14.9 3.0 0.047 12.5 2.1 2.1 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF82504.1 - 0.057 13.4 0.3 0.4 10.7 0.0 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EXF82504.1 - 0.12 11.4 0.0 0.12 11.4 0.0 1.6 2 0 0 2 2 2 0 Thi4 family Glyco_hydro_2_C PF02836.12 EXF82505.1 - 2.1e-101 338.7 0.0 2.8e-101 338.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.12 EXF82505.1 - 1.1e-63 214.8 0.0 1.9e-63 214.0 0.0 1.4 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.13 EXF82505.1 - 1.3e-48 164.7 0.3 2.8e-48 163.6 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EXF82505.1 - 5.3e-16 59.0 0.4 2e-15 57.1 0.2 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 EXF82505.1 - 0.0059 16.8 0.1 0.018 15.2 0.1 1.8 1 0 0 1 1 1 1 Beta-galactosidase jelly roll domain Sugar_tr PF00083.19 EXF82506.1 - 1.2e-93 314.1 24.1 1.7e-93 313.6 16.7 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF82506.1 - 2.7e-30 105.2 23.2 4.6e-30 104.5 15.2 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily Fungal_trans PF04082.13 EXF82506.1 - 1.2e-07 30.8 0.5 3.6e-07 29.3 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain Arylesterase PF01731.15 EXF82507.1 - 0.02 14.8 0.0 0.07 13.1 0.0 2.1 1 0 0 1 1 1 0 Arylesterase Abi_C PF14355.1 EXF82507.1 - 0.09 12.7 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 Abortive infection C-terminus Rdx PF10262.4 EXF82508.1 - 0.082 12.9 0.0 0.24 11.4 0.0 1.8 2 0 0 2 2 2 0 Rdx family E1-E2_ATPase PF00122.15 EXF82509.1 - 3.4e-62 209.4 3.2 5.7e-62 208.7 2.2 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EXF82509.1 - 6.1e-31 107.3 12.0 6.1e-31 107.3 8.3 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EXF82509.1 - 1.4e-29 104.0 0.0 7.3e-28 98.4 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EXF82509.1 - 9.7e-16 57.5 0.0 2.3e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EXF82509.1 - 2.8e-14 52.3 0.0 8.2e-14 50.8 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EXF82509.1 - 1.9e-12 47.7 0.0 4.4e-12 46.5 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EXF82509.1 - 0.00029 20.4 0.2 0.00068 19.2 0.1 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UvdE PF03851.9 EXF82511.1 - 1.4e-113 378.5 0.0 1.9e-113 378.1 0.0 1.2 1 0 0 1 1 1 1 UV-endonuclease UvdE 2_5_RNA_ligase2 PF13563.1 EXF82511.1 - 0.0091 15.7 0.3 0.022 14.4 0.1 1.7 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily Aa_trans PF01490.13 EXF82512.1 - 5.4e-32 110.7 26.5 1.1e-31 109.7 18.4 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein TAFII28 PF04719.9 EXF82513.1 - 3.6e-22 77.9 0.0 3.6e-21 74.7 0.0 2.1 1 1 0 1 1 1 1 hTAFII28-like protein conserved region GTP_cyclohydroI PF01227.17 EXF82514.1 - 3.1e-74 248.1 0.6 4.1e-74 247.7 0.4 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EXF82514.1 - 0.00055 19.8 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 QueF-like protein Ssu72 PF04722.8 EXF82515.1 - 2.2e-84 281.6 0.0 2.5e-84 281.4 0.0 1.0 1 0 0 1 1 1 1 Ssu72-like protein GIT_SHD PF08518.6 EXF82516.1 - 9.7e-21 72.8 6.4 3.9e-12 45.2 2.3 2.5 2 0 0 2 2 2 2 Spa2 homology domain (SHD) of GIT DUF1843 PF08898.5 EXF82516.1 - 0.031 14.2 0.2 0.031 14.2 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1843) PLAC9 PF15205.1 EXF82516.1 - 0.79 10.0 3.5 15 5.9 0.1 3.2 3 0 0 3 3 3 0 Placenta-specific protein 9 FUSC PF04632.7 EXF82516.1 - 2.4 6.4 16.7 0.2 10.0 8.1 1.6 2 0 0 2 2 2 0 Fusaric acid resistance protein family DUF592 PF04574.8 EXF82517.1 - 0.051 13.1 0.0 0.079 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF592) GFA PF04828.9 EXF82519.1 - 3.2e-06 26.9 0.2 4.8e-06 26.4 0.2 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme DZR PF12773.2 EXF82519.1 - 0.09 12.6 1.5 0.17 11.7 1.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon DUF1295 PF06966.7 EXF82520.1 - 6.6e-58 195.7 0.3 8.7e-58 195.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.11 EXF82520.1 - 4.2e-07 29.8 5.0 4.7e-07 29.6 0.0 3.0 1 1 2 4 4 4 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.9 EXF82520.1 - 8.3e-05 22.7 0.8 0.00037 20.6 0.0 2.3 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EXF82520.1 - 0.0012 18.8 3.9 0.0012 18.8 0.0 2.9 3 1 1 4 4 4 1 Phospholipid methyltransferase RNase_P_p30 PF01876.11 EXF82522.1 - 4.3e-43 146.1 0.0 6.1e-43 145.6 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 DUF4547 PF15080.1 EXF82524.1 - 0.01 15.2 0.1 0.014 14.8 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4547) Yip1 PF04893.12 EXF82524.1 - 0.038 13.4 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 Yip1 domain DUF4372 PF14294.1 EXF82524.1 - 0.1 12.5 0.0 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4372) DUF155 PF02582.9 EXF82525.1 - 6.5e-60 202.0 0.1 1.1e-59 201.2 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 E1-E2_ATPase PF00122.15 EXF82526.1 - 5.3e-55 185.9 0.3 1.1e-54 184.8 0.1 1.7 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EXF82526.1 - 3.7e-46 158.2 2.2 7.9e-46 157.1 1.5 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EXF82526.1 - 7.1e-44 147.7 3.8 2.4e-11 43.6 0.0 4.6 4 0 0 4 4 4 4 Heavy-metal-associated domain HAD PF12710.2 EXF82526.1 - 6.1e-15 55.8 0.0 1.6e-14 54.5 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EXF82526.1 - 7.9e-05 22.3 1.5 0.00068 19.2 0.2 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase FAM70 PF14967.1 EXF82526.1 - 0.043 13.0 0.9 26 3.8 0.0 3.5 4 0 0 4 4 4 0 FAM70 protein PIG-P PF08510.7 EXF82526.1 - 0.13 11.8 1.0 18 4.9 0.0 2.4 2 0 0 2 2 2 0 PIG-P PCI PF01399.22 EXF82527.1 - 2.1e-08 34.4 0.0 4.7e-08 33.2 0.0 1.6 2 0 0 2 2 2 1 PCI domain RGS PF00615.14 EXF82528.1 - 1.7e-11 44.2 0.0 3.6e-08 33.5 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain Ribosomal_L31e PF01198.14 EXF82529.1 - 5.2e-36 122.1 1.1 6.5e-36 121.8 0.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e UQ_con PF00179.21 EXF82530.1 - 2.5e-47 159.8 0.0 3e-47 159.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EXF82530.1 - 9.6e-05 22.1 0.0 0.00013 21.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EXF82530.1 - 0.021 14.6 0.1 0.032 14.1 0.1 1.5 1 1 0 1 1 1 0 RWD domain UEV PF05743.8 EXF82530.1 - 0.024 14.3 0.0 0.038 13.6 0.0 1.4 1 1 0 1 1 1 0 UEV domain DUF285 PF03382.9 EXF82531.1 - 0.0098 15.4 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 1 Mycoplasma protein of unknown function, DUF285 C1_2 PF03107.11 EXF82531.1 - 0.2 11.7 8.8 0.38 10.9 6.1 1.4 1 0 0 1 1 1 0 C1 domain Microtub_bind PF13931.1 EXF82531.1 - 0.22 11.6 2.9 0.3 11.2 1.8 1.4 1 1 0 1 1 1 0 Kinesin-associated microtubule-binding zf-HIT PF04438.11 EXF82531.1 - 0.65 9.6 12.5 1.2 8.8 8.7 1.5 1 0 0 1 1 1 0 HIT zinc finger C1_3 PF07649.7 EXF82531.1 - 0.94 9.5 11.5 0.16 12.0 5.1 1.9 2 0 0 2 2 2 0 C1-like domain IBR PF01485.16 EXF82531.1 - 1.1 9.1 10.6 2.6 8.0 7.2 1.6 1 1 0 1 1 1 0 IBR domain Pkinase PF00069.20 EXF82532.1 - 1e-59 201.8 0.0 1.4e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF82532.1 - 1.4e-27 96.3 0.0 2.1e-27 95.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF82532.1 - 4.6e-07 29.0 0.0 6.3e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EXF82532.1 - 0.087 11.8 0.0 0.15 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SprT-like PF10263.4 EXF82533.1 - 0.016 14.8 0.2 0.025 14.2 0.1 1.5 1 1 0 1 1 1 0 SprT-like family TRI5 PF06330.6 EXF82534.1 - 0.0024 16.5 0.0 0.0048 15.6 0.0 1.4 2 0 0 2 2 2 1 Trichodiene synthase (TRI5) HET PF06985.6 EXF82535.1 - 2.8e-21 76.1 0.0 7.8e-17 61.7 0.0 2.4 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) NMT1_2 PF13379.1 EXF82535.1 - 0.064 12.6 0.0 0.097 12.0 0.0 1.2 1 0 0 1 1 1 0 NMT1-like family FAD_binding_4 PF01565.18 EXF82536.1 - 3.2e-20 72.0 3.5 4.9e-20 71.4 1.2 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EXF82536.1 - 6.9e-05 22.6 0.1 0.00016 21.4 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like ThuA PF06283.6 EXF82539.1 - 3.4e-42 144.6 0.4 9.7e-42 143.1 0.3 1.7 1 1 0 1 1 1 1 Trehalose utilisation LysM PF01476.15 EXF82540.1 - 2.3e-23 81.8 3.2 1.4e-07 31.2 0.1 3.2 3 0 0 3 3 3 3 LysM domain UPF0203 PF05254.7 EXF82540.1 - 6.2 6.7 6.9 11 5.9 0.6 2.8 2 2 0 2 2 2 0 Uncharacterised protein family (UPF0203) DUF3316 PF11777.3 EXF82541.1 - 0.013 15.3 0.1 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3316) ChitinaseA_N PF08329.5 EXF82541.1 - 0.041 13.6 0.1 0.096 12.4 0.0 1.6 1 0 0 1 1 1 0 Chitinase A, N-terminal domain Glyco_hydro_18 PF00704.23 EXF82542.1 - 2.9e-43 148.6 1.0 4.7e-43 147.9 0.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Hce2 PF14856.1 EXF82542.1 - 3.6e-29 100.5 1.3 3.6e-29 100.5 0.9 2.1 2 0 0 2 2 2 1 Pathogen effector; putative necrosis-inducing factor LysM PF01476.15 EXF82542.1 - 1.1e-08 34.7 0.1 0.0011 18.8 0.0 2.8 2 0 0 2 2 2 2 LysM domain Chitin_bind_1 PF00187.14 EXF82542.1 - 7.1e-05 22.6 2.1 7.1e-05 22.6 1.5 3.9 4 0 0 4 4 4 1 Chitin recognition protein DUF605 PF04652.11 EXF82543.1 - 1.4 8.2 15.3 2.2 7.5 10.6 1.2 1 0 0 1 1 1 0 Vta1 like OPT PF03169.10 EXF82544.1 - 3.3e-168 560.9 55.7 3.8e-168 560.7 38.6 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3480 PF11979.3 EXF82544.1 - 0.32 9.5 0.3 2.3 6.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3480) 3HCDH_N PF02737.13 EXF82545.1 - 1.4e-29 103.0 0.0 2e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EXF82545.1 - 8.7e-12 45.2 0.0 1.6e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Histidinol_dh PF00815.15 EXF82546.1 - 1.9e-116 389.0 0.0 2.3e-116 388.8 0.0 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase Fungal_trans PF04082.13 EXF82547.1 - 6.1e-05 22.0 1.6 0.00014 20.8 1.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain Acyl_transf_3 PF01757.17 EXF82548.1 - 1.1e-26 93.5 34.0 4.8e-26 91.4 23.6 1.9 1 1 0 1 1 1 1 Acyltransferase family DUF3176 PF11374.3 EXF82549.1 - 1.2e-26 92.7 3.4 3.1e-26 91.4 2.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) DUF1616 PF07760.6 EXF82549.1 - 0.11 11.6 0.3 0.27 10.3 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Abi PF02517.11 EXF82549.1 - 2 8.5 5.1 5.4 7.2 1.6 2.4 2 0 0 2 2 2 0 CAAX protease self-immunity Dioxygenase_N PF04444.9 EXF82550.1 - 3.4e-11 42.9 0.0 4.6e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Catechol dioxygenase N terminus Ribosomal_60s PF00428.14 EXF82551.1 - 2.3 8.6 17.9 0.16 12.3 1.3 3.2 3 1 0 3 3 3 0 60s Acidic ribosomal protein Nucleo_P87 PF07267.6 EXF82551.1 - 8.8 4.8 7.4 5.9 5.4 4.1 1.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 WD40 PF00400.27 EXF82552.1 - 4.1e-70 229.3 14.9 5.8e-11 41.8 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EXF82552.1 - 5.5e-24 84.1 10.8 8.9e-24 83.4 7.5 1.3 1 0 0 1 1 1 1 Tup N-terminal LXG PF04740.7 EXF82552.1 - 0.00073 19.3 1.3 0.0011 18.8 0.9 1.1 1 0 0 1 1 1 1 LXG domain of WXG superfamily Nucleoporin_N PF08801.6 EXF82552.1 - 0.0024 16.6 0.2 0.51 9.0 0.1 3.1 1 1 3 4 4 4 2 Nup133 N terminal like Nup160 PF11715.3 EXF82552.1 - 0.0056 14.8 0.5 0.4 8.7 0.2 3.1 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Myosin_tail_1 PF01576.14 EXF82552.1 - 0.033 11.9 3.8 0.047 11.4 2.6 1.1 1 0 0 1 1 1 0 Myosin tail Nbas_N PF15492.1 EXF82552.1 - 0.033 13.2 0.1 14 4.6 0.0 3.0 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Tektin PF03148.9 EXF82552.1 - 0.056 11.9 3.0 0.078 11.5 2.1 1.1 1 0 0 1 1 1 0 Tektin family Cytochrom_D1 PF02239.11 EXF82552.1 - 0.074 11.3 0.3 0.74 8.0 0.1 2.3 1 1 1 2 2 2 0 Cytochrome D1 heme domain FA_hydroxylase PF04116.8 EXF82553.1 - 2.3e-14 53.7 25.5 2.9e-13 50.2 12.1 2.4 2 1 0 2 2 2 2 Fatty acid hydroxylase superfamily DUF2015 PF09435.5 EXF82554.1 - 2.9e-47 159.6 0.0 3.2e-47 159.4 0.0 1.0 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF2015) Ribosomal_L28e PF01778.12 EXF82555.1 - 1.4e-38 131.8 0.2 1.8e-38 131.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Ldh_1_C PF02866.13 EXF82556.1 - 2.7e-46 157.4 0.0 3.8e-46 156.9 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EXF82556.1 - 1.1e-43 148.4 0.1 1.6e-43 147.9 0.1 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EXF82556.1 - 0.00023 19.9 0.0 0.0004 19.1 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TRAPP PF04051.11 EXF82557.1 - 8.1e-44 148.8 0.0 1.4e-43 148.0 0.0 1.4 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component PINIT PF14324.1 EXF82557.1 - 6.1e-36 123.6 0.0 1.1e-35 122.7 0.0 1.4 1 0 0 1 1 1 1 PINIT domain zf-MIZ PF02891.15 EXF82557.1 - 8.2e-22 76.4 5.9 1.8e-21 75.3 4.1 1.6 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EXF82557.1 - 1.9e-05 24.1 1.6 3.7e-05 23.1 1.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.22 EXF82557.1 - 0.0032 16.9 0.0 0.0074 15.7 0.0 1.6 1 0 0 1 1 1 1 SAP domain zf-C3HC4_4 PF15227.1 EXF82557.1 - 0.08 12.8 5.5 0.19 11.6 3.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EXF82557.1 - 0.83 9.4 3.6 1.7 8.4 2.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DUF2423 PF10338.4 EXF82558.1 - 7.3e-18 64.2 3.6 7.3e-18 64.2 2.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2423) HMG14_17 PF01101.13 EXF82558.1 - 2.4 8.8 12.1 0.47 11.1 2.7 2.5 1 1 1 2 2 2 0 HMG14 and HMG17 GSDH PF07995.6 EXF82561.1 - 0.0002 20.5 0.3 0.00094 18.3 0.2 2.1 1 1 0 1 1 1 1 Glucose / Sorbosone dehydrogenase SGL PF08450.7 EXF82561.1 - 0.00058 19.3 0.0 0.0017 17.7 0.0 1.8 2 0 0 2 2 2 1 SMP-30/Gluconolaconase/LRE-like region NHL PF01436.16 EXF82561.1 - 0.017 15.0 0.0 53 4.0 0.0 4.2 4 0 0 4 4 4 0 NHL repeat GFA PF04828.9 EXF82562.1 - 2.1e-15 56.4 4.5 1.2e-08 34.8 0.0 2.9 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Nudix_N_2 PF14803.1 EXF82562.1 - 0.014 15.0 2.2 4.5 7.0 0.0 3.7 3 0 0 3 3 3 0 Nudix N-terminal zf-NADH-PPase PF09297.6 EXF82562.1 - 0.016 14.6 2.0 0.034 13.6 0.0 2.6 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain zf-ribbon_3 PF13248.1 EXF82562.1 - 0.046 12.9 7.8 1 8.6 0.4 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Rsm1 PF08600.5 EXF82562.1 - 0.068 13.0 0.2 15 5.5 0.0 2.4 2 0 0 2 2 2 0 Rsm1-like zinc_ribbon_2 PF13240.1 EXF82562.1 - 0.22 11.0 7.5 5.4 6.6 0.3 3.7 3 0 0 3 3 3 0 zinc-ribbon domain 2OG-FeII_Oxy_2 PF13532.1 EXF82563.1 - 2.1e-34 119.0 0.0 3e-34 118.5 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-GRF PF06839.7 EXF82563.1 - 1.7e-10 40.6 5.6 2.9e-10 39.8 3.9 1.4 1 0 0 1 1 1 1 GRF zinc finger 2OG-FeII_Oxy PF03171.15 EXF82563.1 - 0.019 15.2 0.0 0.057 13.7 0.0 1.8 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily MIF4G PF02854.14 EXF82563.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 MIF4G domain WD40 PF00400.27 EXF82564.1 - 1.8e-29 100.5 13.5 7.3e-10 38.3 0.0 6.5 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 EXF82564.1 - 0.024 14.4 0.0 0.27 11.0 0.0 2.5 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DEAD PF00270.24 EXF82565.1 - 1.6e-40 138.3 0.0 6.2e-40 136.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF82565.1 - 3.1e-20 71.8 0.5 7.3e-20 70.6 0.3 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EXF82565.1 - 0.097 12.4 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_18 PF13238.1 EXF82566.1 - 0.061 13.6 0.1 0.31 11.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain Pex14_N PF04695.8 EXF82566.1 - 0.13 12.2 4.8 0.32 11.0 3.3 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Abhydrolase_6 PF12697.2 EXF82567.1 - 2.6e-14 53.6 0.0 5.1e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF82567.1 - 1.2e-10 41.3 0.0 5.1e-10 39.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF1100 PF06500.6 EXF82567.1 - 1.5e-07 30.3 0.0 2e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S9 PF00326.16 EXF82567.1 - 5.6e-06 25.7 0.0 1.9e-05 24.0 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EXF82567.1 - 3.2e-05 23.5 0.1 0.00018 21.1 0.0 2.3 2 2 0 2 2 2 1 alpha/beta hydrolase fold AXE1 PF05448.7 EXF82567.1 - 0.00065 18.3 0.0 0.0027 16.2 0.0 1.8 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) BAAT_C PF08840.6 EXF82567.1 - 0.074 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal UPF0227 PF05728.7 EXF82567.1 - 0.075 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Peptidase_M75 PF09375.5 EXF82567.1 - 0.13 11.5 4.8 0.2 10.9 3.3 1.2 1 0 0 1 1 1 0 Imelysin Zn_clus PF00172.13 EXF82568.1 - 1.1e-06 28.4 13.1 2.2e-06 27.4 9.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 EXF82569.1 - 2.8e-64 217.3 0.0 3.4e-64 217.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 polyprenyl_synt PF00348.12 EXF82570.1 - 1.4e-40 138.8 0.0 3.3e-40 137.5 0.0 1.6 1 0 0 1 1 1 1 Polyprenyl synthetase Terpene_synth_C PF03936.11 EXF82570.1 - 5.9e-05 22.4 0.1 0.0011 18.2 0.0 2.3 2 0 0 2 2 2 1 Terpene synthase family, metal binding domain FAD_binding_4 PF01565.18 EXF82571.1 - 9.5e-24 83.4 4.6 2.1e-23 82.3 3.2 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF82571.1 - 0.0023 17.8 0.2 0.0053 16.6 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like MBOAT_2 PF13813.1 EXF82572.1 - 9.6e-18 64.0 3.6 2.4e-17 62.7 2.5 1.7 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Cys_rich_CPCC PF14206.1 EXF82573.1 - 0.07 12.6 2.2 0.19 11.2 1.5 1.7 1 0 0 1 1 1 0 Cysteine-rich CPCC Mito_carr PF00153.22 EXF82574.1 - 4.3e-41 138.5 7.1 3e-17 62.0 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Metallophos PF00149.23 EXF82576.1 - 1.6e-07 30.9 2.0 3.3e-07 29.8 1.3 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase DUF3068 PF11271.3 EXF82576.1 - 0.077 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3068) Glyco_hydro_28 PF00295.12 EXF82577.1 - 2.3e-16 59.6 8.4 6.3e-15 54.9 1.7 2.6 2 1 1 3 3 3 2 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EXF82577.1 - 0.0068 16.1 7.2 0.0068 16.1 5.0 3.0 3 2 0 3 3 3 2 Right handed beta helix region Ribonuclease PF00545.15 EXF82577.1 - 0.083 12.9 0.1 4.8 7.3 0.0 2.6 2 0 0 2 2 2 0 ribonuclease Polysacc_deac_1 PF01522.16 EXF82578.1 - 2.2e-34 117.7 0.0 3.8e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EXF82578.1 - 6.2e-15 54.8 50.9 1.1e-07 31.7 14.3 2.7 2 1 0 2 2 2 2 Chitin recognition protein Glyco_hydro_57 PF03065.10 EXF82578.1 - 1.4e-06 27.4 0.0 3.1e-06 26.3 0.0 1.5 1 1 1 2 2 2 1 Glycosyl hydrolase family 57 Pkinase PF00069.20 EXF82579.1 - 1.2e-11 44.2 0.0 2e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF82579.1 - 3.5e-05 23.0 0.0 0.00027 20.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase CorA PF01544.13 EXF82580.1 - 0.19 10.6 5.0 0.28 10.1 2.4 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein zf-P11 PF03854.9 EXF82581.1 - 0.0042 16.5 3.0 0.0066 15.9 2.1 1.3 1 0 0 1 1 1 1 P-11 zinc finger COX16 PF14138.1 EXF82582.1 - 8.3e-33 112.4 0.3 1.1e-32 111.9 0.2 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 YjgP_YjgQ PF03739.9 EXF82582.1 - 0.11 11.1 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family zf-C2H2_4 PF13894.1 EXF82583.1 - 0.0056 16.9 23.2 0.047 14.0 0.3 5.2 4 1 0 4 4 4 2 C2H2-type zinc finger Transpos_assoc PF13963.1 EXF82583.1 - 0.02 14.8 0.3 0.02 14.8 0.2 2.3 2 0 0 2 2 2 0 Transposase-associated domain zf-C2H2_jaz PF12171.3 EXF82583.1 - 0.24 11.5 11.0 1.1 9.4 1.7 3.5 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EXF82583.1 - 0.25 11.7 23.3 4.9 7.7 0.2 5.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type Kelch_3 PF13415.1 EXF82584.1 - 1.2e-27 95.3 20.0 8e-08 32.2 0.2 8.5 9 1 0 9 9 9 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EXF82584.1 - 2.2e-22 78.5 20.0 1.1e-06 28.2 0.1 7.2 8 0 0 8 8 8 5 Galactose oxidase, central domain Kelch_6 PF13964.1 EXF82584.1 - 8.3e-20 70.0 6.5 5.1e-08 32.7 0.1 5.2 5 2 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 EXF82584.1 - 7.4e-19 67.2 8.6 2.1e-05 24.3 0.0 6.8 7 0 0 7 7 7 3 Kelch motif Kelch_1 PF01344.20 EXF82584.1 - 2.1e-15 55.9 3.4 4.9e-06 25.9 0.0 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.10 EXF82584.1 - 8.3e-12 44.3 7.5 3.7e-06 26.4 0.6 5.9 5 1 0 5 5 5 3 Kelch motif 2Fe-2S_thioredx PF01257.14 EXF82585.1 - 1.9e-58 196.1 0.0 2.4e-58 195.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin AMP-binding PF00501.23 EXF82587.1 - 2.3e-87 293.1 0.1 2.9e-87 292.7 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EXF82587.1 - 5.1e-09 36.9 0.0 1.1e-08 35.9 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SAGA-Tad1 PF12767.2 EXF82588.1 - 2e-49 168.5 0.0 2.7e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 Transcriptional regulator of RNA polII, SAGA, subunit Spc97_Spc98 PF04130.8 EXF82589.1 - 5.1e-123 411.2 0.0 9.1e-123 410.4 0.0 1.4 1 0 0 1 1 1 1 Spc97 / Spc98 family DUF3921 PF13060.1 EXF82589.1 - 0.12 12.2 0.0 0.28 11.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3921) ATP-synt_DE_N PF02823.11 EXF82590.1 - 2.1e-20 72.2 0.1 3.2e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain NOB1_Zn_bind PF08772.6 EXF82591.1 - 0.0004 20.1 1.8 0.00099 18.8 1.2 1.7 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like FYVE PF01363.16 EXF82591.1 - 0.00096 19.0 3.8 0.002 17.9 2.6 1.6 1 0 0 1 1 1 1 FYVE zinc finger zf-B_box PF00643.19 EXF82591.1 - 0.0039 17.0 6.3 0.0039 17.0 4.4 1.9 2 0 0 2 2 1 1 B-box zinc finger zf-C3HC4_3 PF13920.1 EXF82591.1 - 0.0064 16.1 4.1 0.014 15.0 2.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_Tnp_IS91 PF14319.1 EXF82591.1 - 0.0075 15.7 1.1 0.021 14.3 0.8 1.7 1 0 0 1 1 1 1 Transposase zinc-binding domain zf-C3HC4 PF00097.20 EXF82591.1 - 0.0084 15.7 4.4 0.017 14.8 3.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.1 EXF82591.1 - 0.036 13.2 9.7 0.79 9.0 6.9 2.4 1 1 1 2 2 2 0 zinc-ribbon domain zf-RING_5 PF14634.1 EXF82591.1 - 0.1 12.3 5.5 0.21 11.3 3.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zinc_ribbon_2 PF13240.1 EXF82591.1 - 0.12 11.9 7.9 9.8 5.8 0.0 3.1 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4_2 PF13923.1 EXF82591.1 - 0.12 12.3 5.3 0.25 11.3 3.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Siva PF05458.7 EXF82591.1 - 0.18 11.3 6.6 0.038 13.5 1.9 1.8 2 0 0 2 2 2 0 Cd27 binding protein (Siva) UPF0547 PF10571.4 EXF82591.1 - 0.42 10.3 7.0 8.4 6.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Zn-ribbon_8 PF09723.5 EXF82591.1 - 6.7 6.7 8.3 18 5.3 5.7 1.7 1 0 0 1 1 1 0 Zinc ribbon domain TAF8_C PF10406.4 EXF82592.1 - 0.055 13.5 1.0 0.22 11.5 0.0 2.4 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term Sec63 PF02889.11 EXF82593.1 - 7.1e-47 160.1 0.0 7.4e-46 156.8 0.0 2.1 1 1 0 1 1 1 1 Sec63 Brl domain DnaJ PF00226.26 EXF82593.1 - 1.6e-16 59.7 1.8 1.6e-16 59.7 1.2 2.1 2 1 0 2 2 2 1 DnaJ domain OST3_OST6 PF04756.8 EXF82593.1 - 0.097 12.2 0.1 0.18 11.3 0.1 1.4 1 0 0 1 1 1 0 OST3 / OST6 family IncA PF04156.9 EXF82593.1 - 2.2 7.8 5.4 0.61 9.6 0.5 2.2 2 0 0 2 2 2 0 IncA protein DUF4045 PF13254.1 EXF82594.1 - 2.5e-87 293.8 42.8 9e-53 180.0 20.7 7.4 6 2 2 8 8 8 2 Domain of unknown function (DUF4045) Gelsolin PF00626.17 EXF82594.1 - 3.2e-07 29.9 0.0 0.044 13.4 0.0 3.4 3 0 0 3 3 3 2 Gelsolin repeat Arf PF00025.16 EXF82595.1 - 2.5e-67 225.5 0.7 2.7e-67 225.3 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EXF82595.1 - 1.1e-12 47.6 0.0 1.3e-12 47.4 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EXF82595.1 - 1.4e-12 47.0 1.2 3.4e-07 29.2 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EXF82595.1 - 1.6e-10 40.5 0.0 1.9e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EXF82595.1 - 2.9e-10 40.6 0.0 3.9e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EXF82595.1 - 4.1e-09 36.3 0.0 5.2e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EXF82595.1 - 2.6e-08 33.3 0.0 3e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EXF82595.1 - 1e-06 28.2 0.0 9.7e-05 21.8 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EXF82595.1 - 0.0051 17.6 0.2 0.0067 17.2 0.1 1.4 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EXF82595.1 - 0.027 14.1 0.2 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 NACHT domain FeoB_N PF02421.13 EXF82595.1 - 0.03 13.5 0.3 0.071 12.3 0.2 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Dynamin_N PF00350.18 EXF82595.1 - 0.04 13.7 0.0 0.44 10.3 0.0 2.0 2 0 0 2 2 2 0 Dynamin family PduV-EutP PF10662.4 EXF82595.1 - 0.043 13.3 0.1 0.092 12.2 0.1 1.6 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation 6PF2K PF01591.13 EXF82595.1 - 0.11 11.5 0.0 0.25 10.3 0.0 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Acetyltransf_1 PF00583.19 EXF82596.1 - 0.0041 17.1 0.0 0.027 14.4 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF82596.1 - 0.014 15.5 0.0 0.033 14.3 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EXF82596.1 - 0.059 13.4 0.0 0.56 10.3 0.0 2.5 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EXF82596.1 - 0.13 12.0 0.0 0.36 10.6 0.0 1.7 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase DUF2791 PF10923.3 EXF82597.1 - 0.17 10.4 0.0 0.24 9.9 0.0 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) RRXRR PF14239.1 EXF82597.1 - 0.92 8.8 5.7 1.6 8.0 4.0 1.3 1 0 0 1 1 1 0 RRXRR protein Pkinase PF00069.20 EXF82598.1 - 1.3e-59 201.4 0.0 1.8e-59 201.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF82598.1 - 4.5e-20 71.8 0.0 2.3e-19 69.5 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EXF82598.1 - 0.063 12.0 0.1 0.094 11.4 0.1 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase NFRKB_winged PF14465.1 EXF82598.1 - 0.15 11.9 0.0 0.94 9.3 0.0 2.2 2 0 0 2 2 2 0 NFRKB Winged Helix-like Mtc PF03820.12 EXF82599.1 - 5.1e-105 350.5 0.5 2.6e-74 249.6 0.1 2.0 1 1 1 2 2 2 2 Tricarboxylate carrier GMC_oxred_N PF00732.14 EXF82600.1 - 1.6e-57 194.9 0.0 2.4e-57 194.3 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF82600.1 - 3.3e-30 105.2 0.3 7.2e-30 104.1 0.1 1.7 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EXF82600.1 - 1.1e-05 24.4 0.0 0.05 12.4 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF82600.1 - 4.5e-05 22.5 0.1 9.3e-05 21.5 0.0 1.5 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EXF82600.1 - 0.0029 17.7 0.1 1.4 8.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF82600.1 - 0.013 14.3 0.1 0.52 9.1 0.0 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EXF82600.1 - 0.019 14.8 0.0 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF82600.1 - 0.021 13.6 0.7 0.92 8.2 0.2 2.2 2 0 0 2 2 2 0 FAD binding domain NAD_binding_8 PF13450.1 EXF82600.1 - 0.035 14.1 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain MgtE PF01769.11 EXF82601.1 - 0.0034 17.6 2.2 0.0034 17.6 1.5 2.9 2 1 1 3 3 3 1 Divalent cation transporter adh_short PF00106.20 EXF82604.1 - 4.1e-15 56.0 0.1 1e-14 54.8 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EXF82604.1 - 4.3e-07 29.7 0.0 7.4e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF82604.1 - 0.00035 20.0 0.0 0.00085 18.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EXF82604.1 - 0.0078 15.1 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 EXF82604.1 - 0.014 15.2 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EXF82604.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding DUF1593 PF07632.6 EXF82605.1 - 3.1e-88 295.4 0.0 4.2e-88 295.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.10 EXF82605.1 - 0.0028 16.0 0.0 0.0039 15.5 0.0 1.1 1 0 0 1 1 1 1 REJ domain SCP2_2 PF13530.1 EXF82605.1 - 0.077 12.3 0.0 0.33 10.3 0.0 1.9 3 0 0 3 3 3 0 Sterol carrier protein domain Sugar_tr PF00083.19 EXF82606.1 - 4.6e-63 213.3 21.7 5.4e-40 137.3 5.3 2.0 1 1 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EXF82606.1 - 1.7e-13 50.0 38.5 2.7e-12 46.0 20.9 3.1 1 1 2 3 3 3 3 Major Facilitator Superfamily MFS_1_like PF12832.2 EXF82606.1 - 0.002 17.8 6.1 0.027 14.2 0.1 3.9 3 1 1 4 4 4 1 MFS_1 like family adh_short PF00106.20 EXF82607.1 - 6.8e-24 84.6 0.1 2.2e-23 82.9 0.1 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF82607.1 - 6.3e-09 35.7 0.4 3.4e-07 30.1 0.3 2.2 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF82607.1 - 2.9e-05 23.9 0.0 3.6e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EXF82607.1 - 0.00031 20.2 0.0 0.00065 19.2 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EXF82607.1 - 0.0011 17.8 0.0 0.0019 17.1 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EXF82607.1 - 0.012 14.3 0.1 0.016 13.9 0.1 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EXF82607.1 - 0.032 14.2 0.0 0.064 13.2 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding Peptidase_S15 PF02129.13 EXF82608.1 - 9.1e-16 58.0 0.1 1.2e-15 57.6 0.1 1.3 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_6 PF12697.2 EXF82608.1 - 1.1e-13 51.5 5.5 2.2e-13 50.6 3.6 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF82608.1 - 2.1e-12 47.0 0.1 4.7e-12 45.8 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF82608.1 - 6.1e-12 45.2 0.0 1.1e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family AXE1 PF05448.7 EXF82608.1 - 3.8e-06 25.6 0.0 0.0003 19.4 0.0 2.1 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.3 EXF82608.1 - 1.2e-05 25.0 0.0 2.1e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase DUF1100 PF06500.6 EXF82608.1 - 0.00079 18.1 0.0 0.001 17.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Abhydrolase_3 PF07859.8 EXF82608.1 - 0.001 18.7 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EXF82608.1 - 0.0067 16.0 0.0 0.016 14.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold WSC PF01822.14 EXF82609.1 - 6.1e-49 163.8 40.3 5.5e-21 74.2 9.7 3.4 3 0 0 3 3 3 3 WSC domain Amidase PF01425.16 EXF82610.1 - 4.2e-33 114.8 2.8 4.2e-33 114.8 2.0 1.7 2 0 0 2 2 2 1 Amidase DUF1541 PF07563.6 EXF82610.1 - 0.05 13.2 0.3 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) DUF3742 PF12553.3 EXF82611.1 - 0.048 14.1 0.1 0.35 11.3 0.1 2.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3742) PX PF00787.19 EXF82612.1 - 3.6e-16 58.9 0.0 6.2e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 PX domain SNARE PF05739.14 EXF82612.1 - 2.1e-12 46.5 4.0 2.1e-12 46.5 2.8 1.8 2 0 0 2 2 2 1 SNARE domain SlyX PF04102.7 EXF82612.1 - 1.2 9.5 5.2 2.1 8.7 0.6 2.7 2 1 1 3 3 3 0 SlyX YebO PF13974.1 EXF82612.1 - 2.7 7.8 5.0 10 5.9 3.4 1.9 1 1 0 1 1 1 0 YebO-like protein EB1 PF03271.12 EXF82613.1 - 5.1e-18 64.8 1.1 9.5e-18 63.9 0.8 1.5 1 0 0 1 1 1 1 EB1-like C-terminal motif DEAD PF00270.24 EXF82614.1 - 3.4e-43 147.0 1.2 5.1e-43 146.4 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF82614.1 - 8.6e-26 89.6 0.0 3e-25 87.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EXF82614.1 - 3.2e-06 25.8 1.3 1.2e-05 23.9 0.1 2.3 1 1 2 3 3 3 1 Protein of unknown function (DUF1253) AAA_19 PF13245.1 EXF82614.1 - 0.039 13.6 0.3 0.14 11.8 0.2 1.9 1 0 0 1 1 1 0 Part of AAA domain Pectate_lyase PF03211.8 EXF82615.1 - 1.5e-58 197.7 6.9 2.1e-58 197.2 4.8 1.1 1 0 0 1 1 1 1 Pectate lyase Defensin_1 PF00323.14 EXF82615.1 - 2.7 8.4 8.8 4.1 7.8 1.6 2.5 2 0 0 2 2 2 0 Mammalian defensin Tombus_movement PF05318.7 EXF82615.1 - 3.8 8.1 7.7 41 4.8 3.6 2.7 2 0 0 2 2 2 0 Tombusvirus movement protein Beta-lactamase PF00144.19 EXF82616.1 - 3.5e-35 121.6 0.3 5.3e-35 120.9 0.2 1.2 1 0 0 1 1 1 1 Beta-lactamase p450 PF00067.17 EXF82617.1 - 1.7e-69 234.5 0.0 2.3e-69 234.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Sugar_tr PF00083.19 EXF82618.1 - 1.3e-97 327.2 19.4 1.5e-97 327.0 13.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF82618.1 - 3.9e-34 117.9 43.6 3.4e-28 98.3 17.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_2 PF04550.7 EXF82618.1 - 2 8.5 6.7 1.2 9.2 0.8 3.1 4 0 0 4 4 4 0 Phage holin family 2 DUF1206 PF06724.6 EXF82619.1 - 0.034 13.8 0.5 0.14 11.9 0.2 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1206) adh_short PF00106.20 EXF82620.1 - 6.1e-28 97.8 0.7 7.5e-28 97.5 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF82620.1 - 8.8e-28 97.6 0.5 1e-27 97.5 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF82620.1 - 4.6e-15 55.7 0.3 6.2e-15 55.3 0.2 1.1 1 0 0 1 1 1 1 KR domain YjeF_N PF03853.10 EXF82620.1 - 0.056 13.0 0.1 0.14 11.7 0.1 1.7 2 0 0 2 2 2 0 YjeF-related protein N-terminus Death PF00531.17 EXF82620.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 Death domain Glyoxalase_3 PF13468.1 EXF82622.1 - 3.1e-21 76.0 0.0 7.7e-21 74.7 0.0 1.6 2 0 0 2 2 2 1 Glyoxalase-like domain Cellulase PF00150.13 EXF82623.1 - 1.1e-46 159.3 0.0 1.4e-46 158.9 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Lactamase_B_2 PF12706.2 EXF82624.1 - 1.4e-31 109.5 0.0 3.7e-31 108.2 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EXF82624.1 - 2.1e-18 65.5 0.1 1e-17 63.3 0.0 2.1 2 0 0 2 2 2 1 tRNase Z endonuclease Lactamase_B PF00753.22 EXF82624.1 - 5.5e-09 35.9 0.0 1.3e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Flavin_Reduct PF01613.13 EXF82626.1 - 8.8e-16 58.1 0.0 1.8e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Flavin reductase like domain Rubella_E2 PF05749.6 EXF82626.1 - 0.067 12.4 0.1 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Rubella membrane glycoprotein E2 PDEase_II PF02112.10 EXF82627.1 - 3.3e-50 170.8 0.1 4.9e-43 147.3 0.1 3.4 3 1 0 3 3 3 2 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EXF82627.1 - 0.017 14.6 0.0 0.047 13.2 0.0 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EXF82627.1 - 0.15 11.6 3.0 1.1 8.8 1.6 2.2 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Acyl_transf_3 PF01757.17 EXF82629.1 - 1e-30 106.7 29.2 2.5e-30 105.4 20.2 1.6 1 1 0 1 1 1 1 Acyltransferase family AMP-binding PF00501.23 EXF82630.1 - 8.9e-58 195.6 1.6 2.3e-31 108.6 0.0 4.7 3 2 0 3 3 3 3 AMP-binding enzyme Transferase PF02458.10 EXF82632.1 - 2e-18 66.0 0.0 2.6e-18 65.7 0.0 1.0 1 0 0 1 1 1 1 Transferase family Glyco_hydro_81 PF03639.8 EXF82633.1 - 4.4e-177 590.2 6.1 5.3e-177 589.9 4.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 81 Fungal_trans PF04082.13 EXF82634.1 - 5.7e-05 22.1 0.1 6.5e-05 21.9 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain LigB PF02900.13 EXF82635.1 - 8.7e-33 113.4 0.0 1e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Phosphodiest PF01663.17 EXF82636.1 - 6e-15 55.4 2.3 3e-14 53.1 1.6 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EXF82636.1 - 0.00032 20.0 0.0 0.0018 17.5 0.0 1.9 2 0 0 2 2 2 1 Sulfatase Metalloenzyme PF01676.13 EXF82636.1 - 0.00035 20.0 0.0 0.00067 19.1 0.0 1.4 1 0 0 1 1 1 1 Metalloenzyme superfamily Cnd3 PF12719.2 EXF82637.1 - 5.4e-93 311.2 3.4 1.3e-92 310.0 1.8 2.0 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EXF82637.1 - 1.4e-08 34.8 13.9 0.00015 21.9 0.6 5.1 3 2 1 4 4 4 3 HEAT repeats HEAT PF02985.17 EXF82637.1 - 2.7e-06 27.0 9.3 0.11 12.6 0.0 7.7 8 1 1 9 9 9 1 HEAT repeat MMS19_N PF14500.1 EXF82637.1 - 0.0017 17.6 1.6 0.25 10.5 0.0 3.4 2 1 1 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II DUF1546 PF07571.8 EXF82637.1 - 0.024 14.7 0.6 0.87 9.7 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1546) HEAT_EZ PF13513.1 EXF82637.1 - 0.83 10.2 20.1 0.82 10.2 3.8 6.0 4 1 2 6 6 6 0 HEAT-like repeat RRM_1 PF00076.17 EXF82638.1 - 9.9e-57 188.4 0.0 3e-16 58.7 0.0 5.6 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF82638.1 - 7.5e-48 160.3 0.0 4.4e-14 52.2 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF82638.1 - 5.8e-19 67.6 0.7 5.7e-05 22.8 0.0 5.1 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CENP-B_dimeris PF09026.5 EXF82638.1 - 7.4 6.8 29.0 0.11 12.6 6.8 3.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Mg_trans_NIPA PF05653.9 EXF82639.1 - 7.3e-65 218.8 4.6 7.3e-61 205.7 1.5 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA EmrE PF13536.1 EXF82639.1 - 4.8e-05 23.5 0.7 4.8e-05 23.5 0.5 3.2 3 1 1 4 4 4 1 Multidrug resistance efflux transporter EamA PF00892.15 EXF82639.1 - 0.0016 18.4 2.0 0.0016 18.4 1.4 4.2 3 1 1 4 4 4 2 EamA-like transporter family DUF914 PF06027.7 EXF82639.1 - 0.092 11.5 4.3 0.99 8.1 0.1 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF914) DUF4401 PF14351.1 EXF82639.1 - 2.3 7.1 17.8 0.27 10.2 9.1 1.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4401) DUF4231 PF14015.1 EXF82639.1 - 4.6 7.2 0.0 4.6 7.2 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) PBD PF00786.23 EXF82641.1 - 8.6e-05 22.8 0.6 0.016 15.6 0.0 2.9 2 0 0 2 2 2 2 P21-Rho-binding domain HLH PF00010.21 EXF82642.1 - 6e-12 45.0 0.0 1.1e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain MerR-DNA-bind PF09278.6 EXF82642.1 - 0.84 10.0 4.4 2.4 8.6 3.0 1.7 1 0 0 1 1 1 0 MerR, DNA binding AMP-binding PF00501.23 EXF82643.1 - 4.5e-71 239.4 0.0 5.5e-71 239.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EXF82643.1 - 6.9e-17 62.1 0.0 1.6e-16 60.9 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LysR_substrate PF03466.15 EXF82643.1 - 0.14 11.2 0.0 0.31 10.1 0.0 1.6 2 0 0 2 2 2 0 LysR substrate binding domain SSrecog PF03531.9 EXF82644.1 - 5.7e-77 258.0 0.1 6.8e-76 254.4 0.1 2.1 1 1 0 1 1 1 1 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EXF82644.1 - 2.2e-24 85.2 0.1 2e-23 82.1 0.0 2.5 3 0 0 3 3 3 1 Histone chaperone Rttp106-like TATR PF03430.8 EXF82644.1 - 1 7.9 5.5 2.6 6.5 2.5 2.0 2 0 0 2 2 2 0 Trans-activating transcriptional regulator Aldo_ket_red PF00248.16 EXF82645.1 - 4.8e-05 22.3 0.0 6.3e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family GFA PF04828.9 EXF82646.1 - 0.02 14.8 0.0 0.056 13.3 0.0 1.8 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-ribbon_3 PF13248.1 EXF82646.1 - 0.061 12.5 0.5 0.061 12.5 0.4 1.6 2 0 0 2 2 2 0 zinc-ribbon domain Glyco_hydro_1 PF00232.13 EXF82647.1 - 7.9e-153 508.8 0.0 9.3e-153 508.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Glyco_transf_8 PF01501.15 EXF82648.1 - 0.00019 20.8 1.5 0.00062 19.1 1.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EXF82648.1 - 0.0012 18.2 0.0 0.0018 17.7 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative DUF4137 PF13593.1 EXF82650.1 - 1.7e-87 293.4 19.4 2e-87 293.2 13.4 1.0 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Sugar_transport PF06800.7 EXF82650.1 - 0.0072 15.4 7.6 0.0094 15.0 3.9 2.1 2 0 0 2 2 2 1 Sugar transport protein DUF4203 PF13886.1 EXF82651.1 - 2.2e-30 105.7 26.9 2.8e-30 105.3 18.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF4381 PF14316.1 EXF82651.1 - 0.058 13.5 4.7 0.64 10.1 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4381) Autophagy_N PF03986.8 EXF82653.1 - 4.9e-46 156.1 0.1 4.9e-46 156.1 0.0 2.8 4 0 0 4 4 4 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EXF82653.1 - 1.2e-22 79.8 0.3 2.6e-22 78.7 0.2 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EXF82653.1 - 3.9e-14 51.4 0.4 6.3e-14 50.7 0.3 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal zf-C3HC4_3 PF13920.1 EXF82653.1 - 1.1e-07 31.3 4.6 1.1e-07 31.3 3.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EXF82653.1 - 2.9e-07 30.3 10.0 2.9e-07 30.3 6.9 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 EXF82653.1 - 3.9e-07 29.5 2.4 8.7e-07 28.4 1.6 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.1 EXF82653.1 - 5e-07 29.3 7.3 1.2e-06 28.1 5.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EXF82653.1 - 3e-06 26.7 9.1 3e-06 26.7 6.3 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EXF82653.1 - 1.4e-05 24.8 6.8 3.5e-05 23.5 4.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.1 EXF82653.1 - 0.015 15.0 3.6 0.034 13.8 2.5 1.6 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EXF82653.1 - 0.087 12.7 8.3 0.2 11.5 5.8 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Harakiri PF15196.1 EXF82653.1 - 0.097 12.9 0.7 0.25 11.5 0.5 1.8 1 0 0 1 1 1 0 Activator of apoptosis harakiri Mcp5_PH PF12814.2 EXF82654.1 - 2.4e-42 143.7 0.0 4.7e-42 142.7 0.0 1.5 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology IncA PF04156.9 EXF82654.1 - 3.4 7.2 43.6 1.2 8.7 8.8 3.8 3 1 1 4 4 4 0 IncA protein DUF2404 PF10296.4 EXF82655.1 - 4.9e-32 109.9 0.0 1.1e-31 108.7 0.0 1.6 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) DNA_pol_B PF00136.16 EXF82656.1 - 4.3e-98 329.1 0.0 7.2e-98 328.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EXF82656.1 - 3.2e-22 78.8 0.1 5.9e-10 38.5 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EXF82656.1 - 3.6e-17 62.1 5.9 3.6e-17 62.1 4.1 2.3 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta XkdW PF09636.5 EXF82656.1 - 0.026 14.3 0.2 0.071 12.9 0.2 1.7 1 0 0 1 1 1 0 XkdW protein Slu7 PF11708.3 EXF82657.1 - 1.7e-73 247.3 19.8 4.2e-73 246.0 13.7 1.7 1 0 0 1 1 1 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.1 EXF82657.1 - 0.013 15.1 0.7 0.027 14.1 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EXF82657.1 - 0.11 12.4 1.1 0.2 11.6 0.8 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.1 EXF82657.1 - 1.2 8.6 4.2 2.8 7.4 2.9 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF3128 PF11326.3 EXF82657.1 - 7.6 6.7 9.6 1.5 9.0 1.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3128) Ribosomal_S4 PF00163.14 EXF82658.1 - 5.9e-28 97.1 0.6 1.1e-27 96.2 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EXF82658.1 - 4.3e-13 48.4 1.2 4.3e-13 48.4 0.8 2.5 3 0 0 3 3 3 1 S4 domain Ribosomal_L21e PF01157.13 EXF82659.1 - 2.1e-40 136.5 4.4 3.1e-40 135.9 3.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e ANTH PF07651.11 EXF82660.1 - 1e-81 273.7 0.0 1e-81 273.7 0.0 2.4 2 0 0 2 2 2 1 ANTH domain I_LWEQ PF01608.12 EXF82660.1 - 9.2e-64 213.9 8.3 9.2e-64 213.9 5.8 5.2 5 1 0 5 5 5 1 I/LWEQ domain ENTH PF01417.15 EXF82660.1 - 0.00049 19.9 0.0 0.0032 17.3 0.0 2.6 2 0 0 2 2 2 1 ENTH domain Med15 PF09606.5 EXF82660.1 - 4.1 5.4 38.5 8.9 4.3 26.7 1.5 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal HMG_box PF00505.14 EXF82662.1 - 4.3e-22 78.1 1.3 7.1e-22 77.4 0.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EXF82662.1 - 8.9e-08 32.3 0.4 1.8e-07 31.4 0.3 1.4 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 EXF82662.1 - 0.00019 20.8 0.1 0.00026 20.3 0.0 1.2 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 TMEM171 PF15471.1 EXF82662.1 - 0.032 13.0 0.1 0.043 12.6 0.0 1.1 1 0 0 1 1 1 0 Transmembrane protein family 171 Exo_endo_phos_2 PF14529.1 EXF82663.1 - 7.4e-18 64.2 0.0 2.2e-17 62.7 0.0 1.8 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EXF82663.1 - 1.5e-10 41.4 0.0 2.5e-10 40.6 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-GRF PF06839.7 EXF82663.1 - 0.0031 17.3 2.1 0.0079 16.0 1.5 1.7 1 0 0 1 1 1 1 GRF zinc finger COX6A PF02046.10 EXF82664.1 - 1.5e-34 118.3 3.5 7.6e-31 106.4 0.6 2.3 2 0 0 2 2 2 2 Cytochrome c oxidase subunit VIa CIA30 PF08547.7 EXF82665.1 - 1.3e-43 148.5 0.0 1.8e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) RRM_1 PF00076.17 EXF82666.1 - 2.4e-17 62.3 0.1 9.9e-09 34.7 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF82666.1 - 1.1e-11 44.5 0.2 1.3e-05 25.0 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF82666.1 - 1.7e-07 30.9 0.0 0.021 14.6 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRI12 PF06609.8 EXF82667.1 - 4e-43 147.5 14.1 5.4e-43 147.0 9.8 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EXF82667.1 - 1e-24 86.9 38.1 1.6e-23 82.9 26.2 2.2 2 0 0 2 2 2 1 Major Facilitator Superfamily Semialdhyde_dhC PF02774.13 EXF82668.1 - 4.1e-38 131.0 0.0 5.4e-38 130.6 0.0 1.2 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.19 EXF82668.1 - 1.7e-29 102.5 0.0 4.8e-29 101.1 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EXF82668.1 - 0.0018 18.8 0.0 0.0036 17.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold DapB_N PF01113.15 EXF82668.1 - 0.0026 17.6 0.0 0.0066 16.3 0.0 1.7 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Tox-PL PF15644.1 EXF82669.1 - 0.0075 16.9 0.0 0.017 15.8 0.0 1.5 1 0 0 1 1 1 1 Papain fold toxin 1 Sec2p PF06428.6 EXF82671.1 - 6.7e-23 80.4 12.0 6.7e-23 80.4 8.3 2.5 2 0 0 2 2 2 1 GDP/GTP exchange factor Sec2p DUF3348 PF11828.3 EXF82671.1 - 0.52 9.6 17.6 0.06 12.7 6.7 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3348) DUF3584 PF12128.3 EXF82671.1 - 4.8 4.3 29.0 6.6 3.9 20.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) PMT PF02366.13 EXF82672.1 - 4.1e-77 258.8 15.2 4.1e-77 258.8 10.5 1.8 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EXF82672.1 - 2.1e-53 180.7 0.1 3.1e-53 180.1 0.0 1.3 1 0 0 1 1 1 1 MIR domain PRP21_like_P PF12230.3 EXF82673.1 - 5.2e-59 199.5 20.3 1.1e-58 198.4 14.1 1.5 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EXF82673.1 - 7.2e-39 131.2 2.7 1.2e-19 69.6 0.1 2.4 2 0 0 2 2 2 2 Surp module NinF PF05810.7 EXF82673.1 - 0.0029 17.3 0.3 0.0083 15.9 0.2 1.7 1 0 0 1 1 1 1 NinF protein PX PF00787.19 EXF82674.1 - 4.3e-24 84.4 0.0 5e-24 84.2 0.0 1.0 1 0 0 1 1 1 1 PX domain Ribophorin_I PF04597.9 EXF82675.1 - 4.9e-152 506.3 1.6 5.7e-152 506.1 1.1 1.0 1 0 0 1 1 1 1 Ribophorin I Hexokinase_2 PF03727.11 EXF82676.1 - 1.9e-89 299.0 0.0 2.7e-89 298.5 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.16 EXF82676.1 - 4.9e-78 261.1 0.0 1.2e-76 256.6 0.0 2.0 2 0 0 2 2 2 1 Hexokinase TPP_enzyme_N PF02776.13 EXF82676.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain FGGY_N PF00370.16 EXF82676.1 - 0.15 11.3 0.0 0.34 10.1 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain PhnJ PF06007.6 EXF82676.1 - 0.16 10.7 0.0 0.3 9.8 0.0 1.4 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ Ank_2 PF12796.2 EXF82677.1 - 1.8e-05 24.9 0.0 0.00012 22.3 0.0 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) VTC PF09359.5 EXF82678.1 - 9.8e-100 333.2 0.0 1.6e-99 332.5 0.0 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.14 EXF82678.1 - 2.2e-27 96.5 0.5 7.9e-13 48.8 0.0 2.9 1 1 1 2 2 2 2 SPX domain DUF202 PF02656.10 EXF82678.1 - 5.3e-13 48.9 0.6 1.1e-12 47.9 0.4 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF202) TrmB PF01978.14 EXF82678.1 - 0.044 13.4 0.3 0.19 11.4 0.1 2.2 3 0 0 3 3 3 0 Sugar-specific transcriptional regulator TrmB HSP20 PF00011.16 EXF82679.1 - 2.3e-10 40.2 0.0 4.8e-08 32.7 0.0 2.2 1 1 0 1 1 1 1 Hsp20/alpha crystallin family Indigoidine_A PF04227.7 EXF82680.1 - 6.5e-101 337.4 2.0 9.5e-101 336.8 1.4 1.2 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EXF82680.1 - 0.0046 16.1 0.1 0.0094 15.1 0.0 1.6 1 0 0 1 1 1 1 pfkB family carbohydrate kinase MSP1_C PF07462.6 EXF82681.1 - 0.53 8.6 12.1 0.26 9.6 6.9 1.5 1 1 1 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus WD40 PF00400.27 EXF82682.1 - 5.9e-08 32.2 0.1 0.27 11.1 0.0 4.3 4 0 0 4 4 4 3 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EXF82682.1 - 0.022 13.4 0.0 2.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Nup133 N terminal like PD40 PF07676.7 EXF82682.1 - 0.074 12.7 0.1 0.88 9.3 0.0 2.4 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat Sod_Ni PF09055.6 EXF82683.1 - 0.15 12.4 1.1 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 Nickel-containing superoxide dismutase BNIP2 PF12496.3 EXF82683.1 - 2.2 8.4 5.8 3.4 7.8 4.0 1.5 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 COG4 PF08318.7 EXF82685.1 - 1.6e-96 322.9 0.0 2.5e-96 322.3 0.0 1.3 1 0 0 1 1 1 1 COG4 transport protein HSCB_C PF07743.8 EXF82685.1 - 0.061 13.7 2.5 0.79 10.2 0.1 3.2 3 0 0 3 3 3 0 HSCB C-terminal oligomerisation domain Autophagy_Cterm PF10381.4 EXF82685.1 - 4.3 6.5 5.2 11 5.2 0.7 2.4 2 0 0 2 2 2 0 Autophagocytosis associated protein C-terminal E1-E2_ATPase PF00122.15 EXF82686.1 - 1.6e-71 240.0 0.2 5.6e-71 238.2 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EXF82686.1 - 7.8e-43 146.1 1.3 1.6e-42 145.1 0.9 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EXF82686.1 - 1.2e-30 107.5 0.0 3.9e-29 102.5 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EXF82686.1 - 2.1e-20 71.9 0.0 4.4e-20 70.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EXF82686.1 - 1.4e-14 54.7 0.0 4e-14 53.2 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EXF82686.1 - 4.5e-13 48.9 0.0 1.2e-12 47.5 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EXF82686.1 - 0.00025 20.7 0.3 0.00046 19.8 0.2 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Rad21_Rec8_N PF04825.8 EXF82687.1 - 6.6e-37 125.8 0.0 1.3e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EXF82687.1 - 7.4e-09 34.6 0.0 1.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EXF82687.1 - 0.00064 19.3 1.1 0.021 14.4 0.0 2.6 3 0 0 3 3 3 1 ScpA/B protein EXS PF03124.9 EXF82688.1 - 2e-102 342.7 5.9 2.3e-102 342.5 4.1 1.0 1 0 0 1 1 1 1 EXS family Glyco_transf_15 PF01793.11 EXF82689.1 - 1.9e-92 309.7 4.1 2.3e-92 309.4 2.8 1.0 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase NUDIX PF00293.23 EXF82691.1 - 4.6e-14 52.2 0.0 8.2e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain SelB-wing_3 PF09107.6 EXF82691.1 - 0.079 12.3 0.1 0.17 11.3 0.1 1.5 1 0 0 1 1 1 0 Elongation factor SelB, winged helix Ctr PF04145.10 EXF82692.1 - 3.9e-31 108.0 1.3 5.3e-31 107.6 0.9 1.2 1 0 0 1 1 1 1 Ctr copper transporter family 3-HAO PF06052.7 EXF82693.1 - 2.6e-62 208.7 0.0 2.9e-62 208.5 0.0 1.0 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EXF82693.1 - 4.2e-06 26.1 0.0 6.3e-06 25.5 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EXF82693.1 - 0.0019 17.6 0.1 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EXF82693.1 - 0.0045 16.6 0.0 0.0074 15.9 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain RRN7 PF11781.3 EXF82693.1 - 0.073 12.5 0.7 0.35 10.4 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase I-specific transcription initiation factor Rrn7 DZR PF12773.2 EXF82693.1 - 0.13 12.0 1.0 0.34 10.7 0.7 1.7 1 1 0 1 1 1 0 Double zinc ribbon FAA_hydrolase PF01557.13 EXF82694.1 - 4.3e-50 170.1 0.0 5e-50 169.9 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family RCR PF12273.3 EXF82696.1 - 4.1e-19 69.4 23.7 2.1e-18 67.1 16.4 1.9 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF1469 PF07332.6 EXF82696.1 - 0.036 13.7 1.1 0.049 13.3 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Rhabdo_glycop PF00974.13 EXF82696.1 - 0.05 11.8 0.0 0.059 11.5 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein DUF1191 PF06697.7 EXF82696.1 - 0.068 11.9 0.3 0.092 11.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) SKG6 PF08693.5 EXF82696.1 - 0.077 12.3 2.9 0.11 11.7 2.0 1.2 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adeno_E3_CR2 PF02439.10 EXF82696.1 - 0.084 12.4 0.5 0.15 11.6 0.4 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Methyltransf_23 PF13489.1 EXF82698.1 - 2e-17 63.3 0.0 6.6e-17 61.6 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF82698.1 - 2e-08 34.8 0.0 2.8e-07 31.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF82698.1 - 3.5e-07 30.6 0.0 6.7e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF82698.1 - 6.9e-07 29.6 0.0 3e-06 27.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF82698.1 - 8e-07 28.7 0.0 4.4e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF82698.1 - 0.00045 20.5 0.0 0.0011 19.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF82698.1 - 0.014 14.4 0.0 0.031 13.3 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_26 PF13659.1 EXF82698.1 - 0.035 14.1 0.0 0.052 13.5 0.0 1.3 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EXF82698.1 - 0.071 12.4 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 EXF82698.1 - 0.17 11.8 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 EXF82699.1 - 5.3e-18 65.2 0.0 7.6e-18 64.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF82699.1 - 2.1e-09 37.9 0.0 1.2e-08 35.4 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF82699.1 - 3.4e-08 33.2 0.0 9.7e-08 31.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF82699.1 - 6.7e-07 29.7 0.0 3e-06 27.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF82699.1 - 7e-06 26.4 0.0 1.7e-05 25.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF82699.1 - 0.00087 19.6 0.0 0.0046 17.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF82699.1 - 0.001 18.1 0.0 0.0021 17.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Ubie_methyltran PF01209.13 EXF82699.1 - 0.029 13.4 0.0 0.72 8.9 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.13 EXF82699.1 - 0.14 11.3 0.0 0.35 10.0 0.0 1.6 1 0 0 1 1 1 0 O-methyltransferase Chitin_synth_1 PF01644.12 EXF82700.1 - 1e-80 269.2 0.3 1.7e-80 268.5 0.2 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_1N PF08407.6 EXF82700.1 - 2.6e-31 107.1 0.1 7.2e-31 105.7 0.0 1.8 2 0 0 2 2 2 1 Chitin synthase N-terminal Chitin_synth_2 PF03142.10 EXF82700.1 - 8e-22 77.3 2.7 6.5e-17 61.1 0.0 2.5 3 0 0 3 3 3 2 Chitin synthase Glyco_trans_2_3 PF13632.1 EXF82700.1 - 9.2e-07 28.7 10.4 9.1e-06 25.5 7.2 2.5 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EXF82700.1 - 5.9e-06 26.2 0.0 2.1e-05 24.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 PC4 PF02229.11 EXF82701.1 - 5.8e-21 73.4 0.0 9.9e-21 72.7 0.0 1.4 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) YqfQ PF14181.1 EXF82701.1 - 0.13 12.2 4.1 0.14 12.1 0.1 2.0 2 0 0 2 2 2 0 YqfQ-like protein PXA PF02194.10 EXF82702.1 - 5.8e-35 120.5 0.0 5.8e-35 120.5 0.0 2.0 2 0 0 2 2 2 1 PXA domain Nexin_C PF08628.7 EXF82702.1 - 1.2e-21 76.8 0.1 3.9e-21 75.2 0.1 1.9 1 0 0 1 1 1 1 Sorting nexin C terminal PX PF00787.19 EXF82702.1 - 6.5e-07 29.1 0.1 3.5e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 PX domain FliJ PF02050.11 EXF82702.1 - 0.013 15.5 2.4 0.034 14.2 1.7 1.6 1 0 0 1 1 1 0 Flagellar FliJ protein DUF3439 PF11921.3 EXF82702.1 - 8.3 6.1 11.8 46 3.7 7.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Hydantoinase_B PF02538.9 EXF82703.1 - 5.1e-199 661.8 0.1 2.1e-197 656.5 0.1 2.1 1 1 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EXF82703.1 - 2.5e-95 318.9 0.6 4.9e-95 317.9 0.4 1.5 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EXF82703.1 - 1.8e-59 200.1 1.7 7.7e-58 194.8 0.1 2.5 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region Ran_BP1 PF00638.13 EXF82706.1 - 3.7e-12 46.3 0.0 2.3e-11 43.7 0.0 2.2 1 1 0 1 1 1 1 RanBP1 domain Nucleoporin_FG PF13634.1 EXF82706.1 - 1.8e-07 31.3 47.5 2.7e-05 24.3 16.7 8.8 2 1 5 7 7 7 4 Nucleoporin FG repeat region SCP2 PF02036.12 EXF82707.1 - 2.3e-25 88.8 0.2 2.6e-25 88.6 0.2 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EXF82707.1 - 8.5e-06 25.7 0.1 1.1e-05 25.4 0.1 1.1 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Pectate_lyase_3 PF12708.2 EXF82709.1 - 9.9e-36 123.9 28.8 4.5e-25 89.0 0.4 4.5 3 2 1 4 4 4 3 Pectate lyase superfamily protein LETM1 PF07766.8 EXF82710.1 - 4.8e-07 29.1 1.2 7.1e-07 28.5 0.3 1.5 2 0 0 2 2 2 1 LETM1-like protein DLH PF01738.13 EXF82711.1 - 2.6e-16 59.5 0.0 1.1e-12 47.6 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EXF82711.1 - 0.00023 20.9 0.0 0.0003 20.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EXF82711.1 - 0.0027 17.4 0.0 0.35 10.5 0.0 2.2 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 EXF82711.1 - 0.0029 17.2 0.7 0.077 12.5 0.0 2.7 1 1 2 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EXF82711.1 - 0.023 14.5 0.2 0.081 12.7 0.1 2.1 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EXF82711.1 - 0.052 12.9 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.16 EXF82711.1 - 0.15 11.2 0.0 0.27 10.4 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family GAF_2 PF13185.1 EXF82712.1 - 5.7e-06 26.8 0.1 0.025 15.0 0.0 2.6 2 1 0 2 2 2 2 GAF domain GAF PF01590.21 EXF82712.1 - 0.0062 16.6 0.0 0.0078 16.3 0.0 1.3 1 0 0 1 1 1 1 GAF domain FG-GAP PF01839.18 EXF82713.1 - 0.12 12.1 0.3 0.21 11.3 0.2 1.5 1 0 0 1 1 1 0 FG-GAP repeat Spermine_synth PF01564.12 EXF82714.1 - 1e-93 312.7 0.1 1.3e-93 312.4 0.1 1.1 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_31 PF13847.1 EXF82714.1 - 0.00068 19.2 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF82714.1 - 0.00081 19.4 0.0 0.0016 18.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF82714.1 - 0.0016 18.1 0.0 0.052 13.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF82714.1 - 0.0032 18.0 0.0 0.0089 16.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain DUF43 PF01861.11 EXF82714.1 - 0.0059 15.6 0.0 0.0086 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF43 Methyltransf_12 PF08242.7 EXF82714.1 - 0.008 16.6 0.3 0.05 14.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain CMAS PF02353.15 EXF82714.1 - 0.026 13.6 0.1 0.057 12.5 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase G-alpha PF00503.15 EXF82715.1 - 1.3e-26 93.1 0.0 1.4e-26 93.0 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EXF82715.1 - 0.0011 18.1 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_29 PF13555.1 EXF82715.1 - 0.0092 15.4 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EXF82715.1 - 0.013 14.9 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain DAP3 PF10236.4 EXF82715.1 - 0.049 12.5 0.1 0.061 12.2 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 FtsK_SpoIIIE PF01580.13 EXF82715.1 - 0.096 12.1 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family G-alpha PF00503.15 EXF82716.1 - 3.2e-86 289.4 0.0 3.8e-86 289.2 0.0 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EXF82716.1 - 5.1e-09 35.6 0.1 1.1e-08 34.5 0.1 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family CN_hydrolase PF00795.17 EXF82717.1 - 3.7e-29 101.3 0.0 6.5e-29 100.6 0.0 1.4 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Proteasome_A_N PF10584.4 EXF82717.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature FAD_binding_4 PF01565.18 EXF82718.1 - 7.4e-23 80.5 0.6 7.4e-23 80.5 0.4 2.0 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EXF82718.1 - 5.4e-10 39.0 0.0 1.4e-09 37.7 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like BTB PF00651.26 EXF82718.1 - 0.0019 18.1 0.0 0.0038 17.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain p450 PF00067.17 EXF82719.1 - 1e-41 142.9 0.0 2e-41 142.0 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Thioesterase PF00975.15 EXF82720.1 - 1e-22 81.5 1.0 2.8e-22 80.0 0.0 2.1 2 1 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 EXF82720.1 - 5.9e-08 32.8 0.0 8.6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF82720.1 - 0.00014 21.6 0.0 0.00027 20.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EXF82720.1 - 0.00027 20.3 0.0 0.00041 19.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) PGAP1 PF07819.8 EXF82720.1 - 0.0055 16.3 0.0 0.0086 15.6 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_3 PF07859.8 EXF82720.1 - 0.0073 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EXF82720.1 - 0.024 14.2 0.0 0.051 13.1 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold Asp PF00026.18 EXF82721.1 - 5.3e-08 32.4 0.0 1.4e-07 31.1 0.0 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease FAD_binding_3 PF01494.14 EXF82722.1 - 3.5e-32 111.8 0.0 9.8e-32 110.3 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.9 EXF82722.1 - 1.6e-05 23.7 2.8 0.026 13.1 0.3 2.3 1 1 0 2 2 2 2 Tryptophan halogenase NAD_binding_8 PF13450.1 EXF82722.1 - 4.7e-05 23.3 0.7 0.00015 21.7 0.3 2.0 1 1 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF82722.1 - 9e-05 21.5 1.8 0.028 13.3 0.7 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF82722.1 - 9.2e-05 21.5 0.3 0.00025 20.0 0.2 1.6 1 1 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EXF82722.1 - 0.0023 17.0 0.1 0.013 14.6 0.1 2.1 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 EXF82722.1 - 0.0071 16.7 2.5 0.023 15.0 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GCM PF03615.10 EXF82722.1 - 0.052 13.1 0.0 0.084 12.4 0.0 1.3 1 0 0 1 1 1 0 GCM motif protein FAD_binding_2 PF00890.19 EXF82722.1 - 0.055 12.3 0.8 0.1 11.4 0.6 1.4 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 EXF82722.1 - 0.15 11.9 0.1 0.44 10.4 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Zn_clus PF00172.13 EXF82723.1 - 1.1e-05 25.2 11.7 1.7e-05 24.5 8.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF2414 PF10309.4 EXF82725.1 - 1.4e-20 72.7 0.0 2.4e-20 71.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2414) SH3BP5 PF05276.9 EXF82725.1 - 0.0035 16.6 4.8 0.0035 16.6 3.3 1.5 2 0 0 2 2 2 1 SH3 domain-binding protein 5 (SH3BP5) MCPsignal PF00015.16 EXF82725.1 - 0.017 14.6 1.7 0.04 13.4 1.2 1.6 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF773 PF05600.7 EXF82725.1 - 0.02 13.6 4.2 0.033 12.9 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF773) ATG16 PF08614.6 EXF82725.1 - 0.058 13.2 9.9 0.17 11.6 6.8 1.8 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) LXG PF04740.7 EXF82725.1 - 0.094 12.4 2.2 0.24 11.1 1.5 1.7 1 0 0 1 1 1 0 LXG domain of WXG superfamily AAA_13 PF13166.1 EXF82725.1 - 0.1 11.0 2.0 0.15 10.5 1.4 1.1 1 0 0 1 1 1 0 AAA domain DUF3450 PF11932.3 EXF82725.1 - 0.24 10.6 8.2 0.057 12.6 2.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) IncA PF04156.9 EXF82725.1 - 0.66 9.5 19.2 1.3 8.5 8.0 2.2 1 1 1 2 2 2 0 IncA protein Sugarporin_N PF11471.3 EXF82725.1 - 0.87 9.2 8.2 2.9 7.6 0.0 2.6 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension GAS PF13851.1 EXF82725.1 - 0.91 8.6 10.3 0.71 9.0 2.7 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.7 EXF82725.1 - 1.2 8.8 6.4 2.9 7.6 1.2 2.4 1 1 1 2 2 2 0 Laminin Domain II Prominin PF05478.6 EXF82725.1 - 1.8 5.9 1.9 2.5 5.5 1.3 1.1 1 0 0 1 1 1 0 Prominin TSC22 PF01166.13 EXF82725.1 - 3.1 7.8 6.5 0.48 10.4 0.4 2.6 3 0 0 3 3 2 0 TSC-22/dip/bun family CENP-F_leu_zip PF10473.4 EXF82725.1 - 3.7 7.3 16.9 0.46 10.3 6.2 2.3 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6 PF04111.7 EXF82725.1 - 5.2 6.0 9.5 9.2 5.2 6.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 EXF82725.1 - 8.4 5.2 12.9 27 3.5 9.0 1.7 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 EXF82725.1 - 9.1 4.8 10.2 7.9 5.0 4.0 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.14 EXF82725.1 - 9.4 3.9 4.1 15 3.2 2.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF16 PF01519.11 EXF82725.1 - 9.6 6.4 8.6 1.1e+02 3.0 5.9 2.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 IncA PF04156.9 EXF82726.1 - 0.043 13.4 0.9 0.095 12.2 0.6 1.5 1 0 0 1 1 1 0 IncA protein Myb_DNA-binding PF00249.26 EXF82727.1 - 2.1e-21 75.7 0.8 3.4e-11 43.0 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EXF82727.1 - 2.9e-18 65.7 1.9 1.1e-13 51.0 0.0 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF2774 PF11242.3 EXF82727.1 - 0.014 15.3 0.0 0.12 12.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2774) HTH_23 PF13384.1 EXF82727.1 - 0.037 13.6 0.8 0.25 11.0 0.4 2.2 2 0 0 2 2 2 0 Homeodomain-like domain Myb_DNA-bind_4 PF13837.1 EXF82727.1 - 0.3 11.2 2.5 1.7 8.8 0.1 2.8 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain SWIRM PF04433.12 EXF82728.1 - 1.3e-14 54.0 0.0 2.7e-14 53.0 0.0 1.5 1 0 0 1 1 1 1 SWIRM domain AAA_12 PF13087.1 EXF82729.1 - 4e-34 117.7 0.0 6.5e-34 117.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EXF82729.1 - 1.3e-23 83.8 0.7 6.4e-23 81.5 0.5 2.0 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EXF82729.1 - 3.7e-09 36.4 0.1 1.5e-06 27.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EXF82729.1 - 7.2e-08 32.0 0.1 2.1e-07 30.5 0.1 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EXF82729.1 - 8.4e-05 22.6 0.2 1.4 8.8 0.0 3.5 3 0 0 3 3 3 2 AAA ATPase domain PhoH PF02562.11 EXF82729.1 - 0.003 16.8 0.1 0.0054 15.9 0.0 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_33 PF13671.1 EXF82729.1 - 0.0041 17.0 0.5 0.02 14.7 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_22 PF13401.1 EXF82729.1 - 0.0073 16.4 0.0 0.63 10.1 0.0 3.2 3 1 0 3 3 3 1 AAA domain T2SE PF00437.15 EXF82729.1 - 0.035 13.0 0.3 0.08 11.8 0.0 1.6 2 0 0 2 2 2 0 Type II/IV secretion system protein IstB_IS21 PF01695.12 EXF82729.1 - 0.038 13.3 0.0 0.083 12.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_5 PF07728.9 EXF82729.1 - 0.051 13.2 0.0 0.26 10.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) KaiC PF06745.8 EXF82729.1 - 0.059 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 KaiC AAA PF00004.24 EXF82729.1 - 0.073 13.2 1.8 6.1 7.0 0.5 3.2 2 1 1 3 3 3 0 ATPase family associated with various cellular activities (AAA) Helicase_RecD PF05127.9 EXF82729.1 - 0.099 12.2 0.1 0.55 9.8 0.0 2.1 2 0 0 2 2 2 0 Helicase ResIII PF04851.10 EXF82729.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EXF82729.1 - 0.23 10.3 0.0 0.38 9.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) WD40 PF00400.27 EXF82730.1 - 6.4e-18 63.8 1.4 0.013 15.4 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Sugar_tr PF00083.19 EXF82731.1 - 1e-79 268.2 20.9 1.2e-79 268.0 14.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF82731.1 - 7.6e-13 47.9 35.4 7.6e-13 47.9 24.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily F_actin_cap_B PF01115.12 EXF82732.1 - 1.2e-107 358.5 0.0 1.4e-107 358.4 0.0 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit P3A PF08727.6 EXF82732.1 - 0.11 11.8 0.0 0.24 10.7 0.0 1.5 1 0 0 1 1 1 0 Poliovirus 3A protein like BAH PF01426.13 EXF82733.1 - 6.4e-05 22.6 0.1 0.00019 21.1 0.0 1.8 1 1 1 2 2 2 1 BAH domain PHD PF00628.24 EXF82733.1 - 0.0013 18.3 2.8 0.0033 17.0 2.0 1.7 1 0 0 1 1 1 1 PHD-finger VEGF_C PF14554.1 EXF82733.1 - 0.01 15.5 2.2 0.026 14.3 1.5 1.6 1 0 0 1 1 1 0 VEGF heparin-binding domain Lipoprotein_20 PF13942.1 EXF82733.1 - 0.02 14.4 0.7 2 7.9 0.1 2.3 2 0 0 2 2 2 0 YfhG lipoprotein FANCL_C PF11793.3 EXF82733.1 - 0.029 14.3 1.7 0.029 14.3 1.2 1.8 2 0 0 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H PF13771.1 EXF82733.1 - 0.03 14.4 1.7 0.067 13.3 1.2 1.6 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING-like PF08746.6 EXF82733.1 - 5.9 6.9 7.3 0.18 11.8 0.3 2.0 2 0 0 2 2 2 0 RING-like domain ATG22 PF11700.3 EXF82734.1 - 1.7e-201 669.8 11.8 2e-201 669.6 8.2 1.0 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like MFS_1 PF07690.11 EXF82734.1 - 5.1e-07 28.7 41.1 0.00076 18.2 2.0 3.2 2 1 1 3 3 3 3 Major Facilitator Superfamily DUF1469 PF07332.6 EXF82734.1 - 0.1 12.2 0.1 0.1 12.2 0.1 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1469) DUF3602 PF12223.3 EXF82735.1 - 3.3e-17 62.6 18.5 1.6e-12 47.6 2.1 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) Ank_2 PF12796.2 EXF82736.1 - 1.1e-79 262.7 1.2 4e-17 62.3 0.0 6.5 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EXF82736.1 - 3.3e-67 219.1 14.2 4e-08 32.6 0.0 13.4 12 2 1 13 13 13 10 Ankyrin repeat Ank_4 PF13637.1 EXF82736.1 - 4.1e-54 180.0 4.8 1.2e-09 38.4 0.1 10.6 3 1 8 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF82736.1 - 1.3e-49 161.2 5.9 3.9e-06 26.5 0.0 11.8 11 0 0 11 11 11 10 Ankyrin repeat Ank_5 PF13857.1 EXF82736.1 - 2.8e-48 160.8 12.5 1.2e-07 31.7 0.0 9.7 2 2 9 12 12 12 8 Ankyrin repeats (many copies) DUF4635 PF15466.1 EXF82736.1 - 0.005 16.1 0.4 0.011 14.9 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4635) Syntaxin-6_N PF09177.6 EXF82736.1 - 0.031 14.6 2.3 0.068 13.5 0.9 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF948 PF06103.6 EXF82736.1 - 0.1 12.4 3.8 5.9 6.8 0.2 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DRMBL PF07522.9 EXF82738.1 - 5.4e-34 116.5 0.0 1.2e-33 115.3 0.0 1.6 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EXF82738.1 - 4.7e-12 45.8 0.0 1e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EXF82738.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily LSM PF01423.17 EXF82739.1 - 2.7e-15 55.6 0.9 3.7e-15 55.2 0.6 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EXF82739.1 - 0.0013 18.6 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Gemin7 PF11095.3 EXF82739.1 - 0.051 13.3 0.0 0.082 12.6 0.0 1.4 1 1 0 1 1 1 0 Gem-associated protein 7 (Gemin7) OGG_N PF07934.7 EXF82740.1 - 1.2e-35 121.9 0.1 2.3e-35 121.0 0.0 1.5 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EXF82740.1 - 1.1e-16 61.0 0.0 1.9e-16 60.2 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EXF82740.1 - 0.00053 19.5 0.0 0.0015 18.1 0.0 1.8 1 0 0 1 1 1 1 Helix-hairpin-helix motif SF3b1 PF08920.5 EXF82741.1 - 5.3e-37 127.0 0.8 5.3e-37 127.0 0.6 2.4 1 1 1 2 2 2 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EXF82741.1 - 9.7e-15 54.6 2.8 0.01 16.1 0.0 7.4 6 3 3 9 9 9 5 HEAT repeats HEAT PF02985.17 EXF82741.1 - 8.9e-11 40.9 9.7 0.95 9.7 0.0 9.5 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.1 EXF82741.1 - 1.7e-10 41.0 3.5 0.32 11.5 0.0 7.8 6 2 2 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EXF82741.1 - 3.3e-05 24.1 0.2 0.58 10.5 0.0 5.3 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EXF82741.1 - 0.00071 18.0 0.2 0.21 9.8 0.0 3.2 2 2 1 3 3 3 2 Adaptin N terminal region UPF0236 PF06782.6 EXF82741.1 - 0.0056 15.1 0.0 0.0092 14.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0236) NUC173 PF08161.7 EXF82741.1 - 0.0083 15.4 0.8 3.7 6.8 0.0 3.7 4 1 0 4 4 4 1 NUC173 domain CLASP_N PF12348.3 EXF82741.1 - 0.019 14.3 0.1 1.3 8.2 0.0 3.5 4 0 0 4 4 4 0 CLASP N terminal zf-C2HC5 PF06221.8 EXF82742.1 - 8.6e-21 73.4 4.9 1.4e-20 72.8 3.4 1.3 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type FAM176 PF14851.1 EXF82742.1 - 0.22 11.1 2.7 0.47 10.1 1.8 1.5 1 0 0 1 1 1 0 FAM176 family Whi5 PF08528.6 EXF82743.1 - 1.3e-08 34.1 0.0 2.3e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Whi5 like Rick_17kDa_Anti PF05433.10 EXF82744.1 - 4.1e-05 23.1 16.1 4.1e-05 23.1 11.2 2.6 2 0 0 2 2 2 2 Glycine zipper 2TM domain DUF2076 PF09849.4 EXF82744.1 - 0.00075 19.6 7.1 0.00075 19.6 4.9 1.4 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Gly-zipper_OmpA PF13436.1 EXF82744.1 - 0.71 9.5 11.7 0.86 9.2 4.9 2.2 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Glyco_hydro_3 PF00933.16 EXF82745.1 - 9.3e-87 290.7 0.0 1.5e-86 290.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF82745.1 - 1.9e-59 200.9 0.5 2.9e-58 197.0 0.2 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF82745.1 - 1.7e-23 82.3 0.0 4.4e-23 81.0 0.0 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain Pilin PF00114.14 EXF82745.1 - 0.18 12.5 3.5 15 6.3 0.0 3.4 3 0 0 3 3 3 0 Pilin (bacterial filament) Tannase PF07519.6 EXF82746.1 - 1.5e-51 175.5 0.1 1.7e-51 175.4 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EXF82746.1 - 0.0056 16.5 0.0 0.0082 16.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family MFS_1 PF07690.11 EXF82747.1 - 6.9e-25 87.5 28.1 6.9e-25 87.5 19.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily PHD PF00628.24 EXF82748.1 - 0.044 13.4 0.7 0.044 13.4 0.5 3.4 3 0 0 3 3 3 0 PHD-finger Lipase_GDSL PF00657.17 EXF82749.1 - 4.1e-14 52.9 0.0 6e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EXF82749.1 - 2.9e-11 43.8 0.4 4.6e-11 43.1 0.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 EXF82749.1 - 0.082 12.6 0.0 0.28 10.9 0.0 1.8 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family DAO PF01266.19 EXF82750.1 - 1.3e-25 90.0 0.0 5.9e-23 81.3 0.0 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase SBP_bac_3 PF00497.15 EXF82751.1 - 1.6e-30 106.0 0.0 2e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Strumpellin PF10266.4 EXF82751.1 - 0.31 8.3 0.6 0.42 7.9 0.4 1.1 1 0 0 1 1 1 0 Hereditary spastic paraplegia protein strumpellin Methyltransf_23 PF13489.1 EXF82753.1 - 1.6e-10 40.9 0.2 8e-10 38.6 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF82753.1 - 0.0056 17.2 0.0 0.39 11.3 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF82753.1 - 0.0084 15.7 0.1 0.65 9.5 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF82753.1 - 0.039 14.4 0.0 0.25 11.8 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain 3H PF02829.9 EXF82753.1 - 0.089 12.8 0.0 0.42 10.6 0.0 2.0 2 0 0 2 2 2 0 3H domain BNR_2 PF13088.1 EXF82754.1 - 1.4e-11 44.2 0.0 5.1e-07 29.2 0.1 2.8 1 1 1 3 3 3 2 BNR repeat-like domain BNR PF02012.15 EXF82754.1 - 1.5e-11 42.2 13.6 0.13 12.2 0.3 6.7 6 0 0 6 6 6 4 BNR/Asp-box repeat Mo-co_dimer PF03404.11 EXF82754.1 - 0.34 10.5 1.0 93 2.6 0.1 3.8 3 1 0 4 4 4 0 Mo-co oxidoreductase dimerisation domain Lipase_GDSL PF00657.17 EXF82756.1 - 2.9e-12 46.9 0.2 3.7e-12 46.5 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EXF82756.1 - 3.5e-09 37.0 0.2 4.4e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Glyco_hydro_6 PF01341.12 EXF82757.1 - 5e-97 324.9 2.5 5.8e-97 324.7 1.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 MFS_1 PF07690.11 EXF82758.1 - 1.5e-16 60.1 38.7 8.3e-14 51.0 11.7 2.4 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF82758.1 - 8.1e-08 31.2 9.2 8.1e-08 31.2 6.4 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter DUF3290 PF11694.3 EXF82758.1 - 0.0064 16.2 0.1 0.023 14.4 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3290) DUF3188 PF11384.3 EXF82758.1 - 3.6 7.2 9.3 1.7 8.2 0.2 3.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3188) DUF1399 PF07173.7 EXF82759.1 - 5.2e-18 65.6 2.8 8e-14 52.0 0.2 3.5 2 1 0 2 2 2 2 Protein of unknown function (DUF1399) TGT PF01702.13 EXF82759.1 - 0.15 11.3 1.1 4.1 6.6 0.2 2.3 2 0 0 2 2 2 0 Queuine tRNA-ribosyltransferase NUDIX PF00293.23 EXF82761.1 - 1.4e-12 47.4 0.0 4.3e-10 39.3 0.0 2.6 2 0 0 2 2 2 2 NUDIX domain Slx4 PF09494.5 EXF82762.1 - 1.9e-22 78.7 0.0 4.5e-22 77.5 0.0 1.6 2 0 0 2 2 2 1 Slx4 endonuclease AT_hook PF02178.14 EXF82762.1 - 0.25 11.1 29.5 0.03 13.9 2.7 4.9 3 0 0 3 3 3 0 AT hook motif Ribosomal_S21e PF01249.13 EXF82763.1 - 1.1e-40 137.3 0.0 1.2e-40 137.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e MFS_1 PF07690.11 EXF82764.1 - 6.1e-33 113.9 31.2 7.5e-33 113.6 21.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 EXF82764.1 - 0.021 15.2 0.0 0.05 13.9 0.0 1.7 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) COesterase PF00135.23 EXF82765.1 - 1.9e-95 320.6 0.0 2.4e-95 320.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF82765.1 - 3.5e-07 29.9 0.0 1.1e-06 28.3 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF82765.1 - 0.00052 19.7 0.0 0.00092 18.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF82765.1 - 0.00071 19.5 0.1 0.0016 18.4 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Malic_M PF03949.10 EXF82766.1 - 2.3e-79 266.5 0.0 3e-79 266.1 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EXF82766.1 - 2e-62 209.9 0.0 2.9e-62 209.4 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain DUF187 PF02638.10 EXF82766.1 - 0.072 11.9 0.1 4.6 5.9 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase like GH101 DUF2413 PF10310.4 EXF82767.1 - 5.1e-141 470.5 0.0 7e-141 470.0 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2413) Flu_M1_C PF08289.6 EXF82767.1 - 0.031 14.2 0.3 0.088 12.8 0.2 1.7 1 0 0 1 1 1 0 Influenza Matrix protein (M1) C-terminal domain Ribosomal_L14 PF00238.14 EXF82769.1 - 4.8e-32 110.2 0.0 5.4e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e FAD_binding_4 PF01565.18 EXF82770.1 - 1e-27 96.3 2.0 1.5e-27 95.7 1.4 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF82770.1 - 1.2e-12 47.5 0.0 2.3e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Macscav_rec PF03523.8 EXF82770.1 - 0.13 12.0 0.9 0.35 10.6 0.1 2.0 2 0 0 2 2 2 0 Macrophage scavenger receptor XLF PF09302.6 EXF82771.1 - 5.9e-27 94.5 0.1 8.1e-27 94.0 0.1 1.2 1 0 0 1 1 1 1 XLF (XRCC4-like factor) GAGA PF09237.6 EXF82771.1 - 0.084 12.4 0.4 0.21 11.1 0.3 1.6 1 0 0 1 1 1 0 GAGA factor Fork_head PF00250.13 EXF82772.1 - 3.4e-16 59.0 0.1 9.7e-16 57.5 0.1 1.7 1 0 0 1 1 1 1 Fork head domain RNF111_N PF15303.1 EXF82772.1 - 0.0034 16.9 3.0 0.0034 16.9 2.1 2.0 2 0 0 2 2 2 1 E3 ubiquitin-protein ligase Arkadia N-terminus Cactin_mid PF10312.4 EXF82773.1 - 8.7e-63 211.0 6.8 1.2e-62 210.5 4.7 1.2 1 0 0 1 1 1 1 Conserved mid region of cactin CactinC_cactus PF09732.4 EXF82773.1 - 1.2e-49 167.0 1.2 2.1e-49 166.2 0.8 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein DUF1087 PF06465.8 EXF82773.1 - 0.14 12.1 1.9 1.4 8.8 0.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1087) YolD PF08863.5 EXF82773.1 - 0.17 11.7 0.7 0.46 10.3 0.0 1.9 2 0 0 2 2 2 0 YolD-like protein FAD_binding_7 PF03441.9 EXF82774.1 - 1.1e-102 343.0 1.3 1.6e-102 342.4 0.1 1.8 3 0 0 3 3 3 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EXF82774.1 - 7.7e-38 129.8 0.1 1.4e-37 128.9 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Cellulase PF00150.13 EXF82775.1 - 1.6e-52 178.4 7.4 2.2e-52 178.0 5.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EXF82775.1 - 2.4e-12 46.3 13.3 2.4e-12 46.3 9.2 2.8 3 0 0 3 3 3 1 Fungal cellulose binding domain Hemerythrin PF01814.18 EXF82776.1 - 1.1e-09 38.5 0.0 1.7e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain adh_short PF00106.20 EXF82777.1 - 1.9e-12 47.3 0.0 3.1e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF82777.1 - 1.7e-05 24.7 0.0 2.1e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF82777.1 - 4.9e-05 23.0 0.0 6.1e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF82777.1 - 0.00024 20.6 0.0 0.00041 19.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Beta-lactamase PF00144.19 EXF82778.1 - 2.2e-65 220.8 0.0 2.8e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Beta-lactamase Zn_clus PF00172.13 EXF82779.1 - 4e-08 33.0 12.3 8.9e-08 31.9 8.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dabb PF07876.7 EXF82781.1 - 1.7e-05 25.1 0.0 2.1e-05 24.8 0.0 1.3 1 1 0 1 1 1 1 Stress responsive A/B Barrel Domain Uds1 PF15456.1 EXF82782.1 - 0.025 14.5 0.3 0.045 13.7 0.2 1.4 1 0 0 1 1 1 0 Up-regulated During Septation 2OG-FeII_Oxy_3 PF13640.1 EXF82784.1 - 2.2e-07 31.2 0.0 3.7e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EXF82784.1 - 3e-06 26.7 0.0 6.2e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EXF82784.1 - 0.058 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily RdRP PF05183.7 EXF82785.1 - 4.3e-179 596.9 0.0 5.5e-179 596.5 0.0 1.1 1 0 0 1 1 1 1 RNA dependent RNA polymerase RRM_1 PF00076.17 EXF82785.1 - 8e-06 25.4 0.0 4.1e-05 23.1 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF82785.1 - 0.0023 17.8 0.0 0.15 12.0 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) FAD-oxidase_C PF02913.14 EXF82786.1 - 9.3e-59 198.7 0.1 1.8e-58 197.8 0.0 1.5 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EXF82786.1 - 5.4e-34 116.6 0.1 1.4e-33 115.2 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain SLA_LP_auto_ag PF05889.8 EXF82786.1 - 0.16 10.4 0.0 0.25 9.7 0.0 1.2 1 0 0 1 1 1 0 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Pkinase PF00069.20 EXF82788.1 - 2.9e-36 124.9 0.0 5.5e-36 124.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF82788.1 - 1.5e-07 30.7 0.0 3.1e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EXF82788.1 - 0.00016 21.4 0.2 0.083 12.6 0.0 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family zf-RING_2 PF13639.1 EXF82789.1 - 3.4e-09 36.3 7.9 6.5e-09 35.4 5.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EXF82789.1 - 2.7e-07 30.5 2.0 6.1e-07 29.4 1.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger FANCL_C PF11793.3 EXF82789.1 - 9.7e-06 25.4 8.4 2.8e-05 23.9 5.8 1.8 1 1 0 1 1 1 1 FANCL C-terminal domain zf-Apc11 PF12861.2 EXF82789.1 - 0.00024 20.8 2.4 0.00064 19.5 1.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger C1_1 PF00130.17 EXF82789.1 - 0.00099 18.7 2.5 0.00099 18.7 1.7 1.7 1 1 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RINGv PF12906.2 EXF82789.1 - 0.0011 19.0 8.1 0.0023 17.9 5.6 1.6 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4 PF00097.20 EXF82789.1 - 0.0013 18.3 9.7 0.0027 17.3 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EXF82789.1 - 0.005 16.4 5.5 0.0093 15.6 3.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EXF82789.1 - 0.0053 16.7 9.1 0.011 15.7 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING-like PF08746.6 EXF82789.1 - 0.11 12.4 7.7 0.24 11.4 5.3 1.6 1 0 0 1 1 1 0 RING-like domain Baculo_RING PF05883.6 EXF82789.1 - 0.14 11.9 1.3 0.3 10.9 0.9 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_5 PF14634.1 EXF82789.1 - 0.4 10.4 8.9 0.73 9.6 6.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain PHD PF00628.24 EXF82789.1 - 4 7.2 7.0 8.3 6.1 4.8 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 EXF82789.1 - 5.2 6.7 7.6 98 2.6 5.2 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4407 PF14362.1 EXF82790.1 - 4.6 6.1 6.4 23 3.8 4.4 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L1 PF00687.16 EXF82793.1 - 3.7e-59 199.7 0.5 3.7e-59 199.7 0.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L1p/L10e family Palm_thioest PF02089.10 EXF82794.1 - 9e-54 182.2 0.0 1.1e-53 181.9 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_6 PF12697.2 EXF82794.1 - 0.00049 20.0 0.0 0.0009 19.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 EXF82794.1 - 0.0043 16.1 0.0 0.045 12.8 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.13 EXF82794.1 - 0.019 14.2 0.0 0.033 13.5 0.0 1.5 1 1 0 1 1 1 0 Lipase (class 2) Cyclin_N PF00134.18 EXF82795.1 - 1.3e-09 37.6 0.1 2.5e-09 36.7 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Yos1 PF08571.5 EXF82795.1 - 0.016 15.2 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Yos1-like Abhydrolase_4 PF08386.5 EXF82797.1 - 3.4e-17 62.2 0.0 7e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Abhydrolase_1 PF00561.15 EXF82797.1 - 8.4e-14 51.6 0.0 4.9e-13 49.1 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EXF82797.1 - 2.4e-08 34.1 0.0 1.9e-07 31.2 0.0 2.3 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF82797.1 - 0.0028 17.4 0.0 0.038 13.7 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family RTA1 PF04479.8 EXF82798.1 - 7.1e-37 127.0 3.6 1.2e-36 126.3 2.5 1.3 1 0 0 1 1 1 1 RTA1 like protein UCR_TM PF02921.9 EXF82798.1 - 0.083 13.1 0.5 0.21 11.8 0.3 1.6 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region TctA PF01970.11 EXF82798.1 - 0.12 10.7 8.0 0.0071 14.7 1.3 1.9 1 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctA family Fungal_trans PF04082.13 EXF82799.1 - 4.3e-20 71.6 0.3 6.4e-20 71.1 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ketoacyl-synt PF00109.21 EXF82799.1 - 5.9e-06 25.9 0.0 9.3e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Gar1 PF04410.9 EXF82800.1 - 6e-43 145.9 0.4 6e-43 145.9 0.3 2.1 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region DUF4266 PF14086.1 EXF82800.1 - 0.71 10.4 10.1 0.15 12.5 0.5 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) GRP PF07172.6 EXF82800.1 - 0.93 10.0 16.7 2 8.9 3.6 2.4 2 0 0 2 2 2 0 Glycine rich protein family Cwf_Cwc_15 PF04889.7 EXF82800.1 - 6.4 6.4 12.0 1.1 8.9 2.3 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein SH3_9 PF14604.1 EXF82801.1 - 2.3e-10 39.8 0.0 3.5e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EXF82801.1 - 5.9e-06 25.5 0.0 9.7e-06 24.8 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EXF82801.1 - 8.4e-05 21.9 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SKG6 PF08693.5 EXF82801.1 - 0.00098 18.3 0.0 0.00098 18.3 0.0 2.7 3 0 0 3 3 2 1 Transmembrane alpha-helix domain Protocadherin PF08374.6 EXF82801.1 - 0.0024 17.5 0.0 0.0054 16.3 0.0 1.5 1 0 0 1 1 1 1 Protocadherin Rifin_STEVOR PF02009.11 EXF82801.1 - 0.0073 15.9 0.4 0.012 15.2 0.3 1.3 1 0 0 1 1 1 1 Rifin/stevor family Glycophorin_A PF01102.13 EXF82801.1 - 0.013 15.3 6.2 0.057 13.1 4.2 2.2 1 1 0 1 1 1 0 Glycophorin A ATG22 PF11700.3 EXF82801.1 - 0.016 13.6 0.1 0.023 13.1 0.1 1.1 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like DUF4448 PF14610.1 EXF82801.1 - 0.06 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) CD34_antigen PF06365.7 EXF82801.1 - 0.069 12.7 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family DUF912 PF06024.7 EXF82801.1 - 0.099 12.6 0.9 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4293 PF14126.1 EXF82801.1 - 0.14 12.0 0.1 0.22 11.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) Syndecan PF01034.15 EXF82801.1 - 0.18 11.4 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Amnionless PF14828.1 EXF82801.1 - 0.21 10.0 0.0 0.3 9.5 0.0 1.1 1 0 0 1 1 1 0 Amnionless Plasmodium_Vir PF05795.6 EXF82801.1 - 2.2 7.4 2.7 3.5 6.7 1.8 1.4 1 1 0 1 1 1 0 Plasmodium vivax Vir protein Ribonucleas_3_3 PF14622.1 EXF82803.1 - 2.4e-05 24.3 0.0 0.069 13.1 0.0 2.4 2 0 0 2 2 2 2 Ribonuclease-III-like dsrm PF00035.20 EXF82803.1 - 0.0026 18.3 0.0 0.005 17.3 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding motif Ribonuclease_3 PF00636.21 EXF82803.1 - 0.0027 18.1 0.0 0.0067 16.8 0.0 1.7 1 1 0 1 1 1 1 Ribonuclease III domain PLA2_B PF01735.13 EXF82804.1 - 1.2e-27 96.2 0.0 2.9e-27 94.9 0.0 1.5 1 1 0 1 1 1 1 Lysophospholipase catalytic domain Septin PF00735.13 EXF82805.1 - 7.3e-122 405.7 0.1 7.3e-122 405.7 0.1 1.8 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EXF82805.1 - 3.3e-07 30.2 0.0 7.1e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EXF82805.1 - 1.8e-05 24.2 2.0 0.00062 19.2 0.0 3.0 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EXF82805.1 - 7.5e-05 21.9 0.5 0.00062 18.9 0.4 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF258 ABC_tran PF00005.22 EXF82805.1 - 0.00014 22.2 2.5 0.018 15.3 0.0 2.6 3 0 0 3 3 3 1 ABC transporter AAA_10 PF12846.2 EXF82805.1 - 0.00041 19.8 1.6 0.0013 18.2 1.1 2.0 1 1 0 1 1 1 1 AAA-like domain AIG1 PF04548.11 EXF82805.1 - 0.0007 18.7 1.5 0.0018 17.4 0.0 2.2 2 0 0 2 2 2 1 AIG1 family Miro PF08477.8 EXF82805.1 - 0.0024 18.3 0.0 0.01 16.3 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein AAA_16 PF13191.1 EXF82805.1 - 0.0024 17.8 0.0 0.013 15.5 0.0 2.1 3 0 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.1 EXF82805.1 - 0.0027 17.8 0.2 0.021 14.9 0.0 2.5 1 1 0 2 2 2 1 AAA domain Ras PF00071.17 EXF82805.1 - 0.0039 16.5 0.1 0.031 13.6 0.0 2.3 2 0 0 2 2 2 1 Ras family AAA_29 PF13555.1 EXF82805.1 - 0.0073 15.8 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EXF82805.1 - 0.022 14.2 0.0 0.022 14.2 0.0 2.9 4 0 0 4 4 4 0 FtsK/SpoIIIE family Dynamin_N PF00350.18 EXF82805.1 - 0.042 13.6 8.2 0.52 10.1 0.0 3.5 3 1 0 3 3 2 0 Dynamin family RNA_helicase PF00910.17 EXF82805.1 - 0.044 13.9 0.6 0.48 10.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase ATP_bind_1 PF03029.12 EXF82805.1 - 0.051 13.1 0.0 10 5.5 0.0 3.0 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein V_ATPase_I PF01496.14 EXF82805.1 - 0.055 11.3 4.3 2.7 5.7 6.0 1.5 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.10 EXF82805.1 - 0.062 12.4 7.1 0.12 11.5 4.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit AAA_25 PF13481.1 EXF82805.1 - 0.075 12.4 0.0 0.29 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EXF82805.1 - 0.091 12.4 1.4 0.22 11.2 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.1 EXF82805.1 - 0.11 12.1 1.1 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 AAA domain Strep_SA_rep PF06696.6 EXF82805.1 - 0.14 11.9 2.8 0.2 11.4 0.9 2.1 1 1 1 2 2 2 0 Streptococcal surface antigen repeat AAA_32 PF13654.1 EXF82805.1 - 0.16 10.5 11.4 0.43 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain Phage_GPO PF05929.6 EXF82805.1 - 0.39 9.9 5.7 0.61 9.2 4.0 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase IncA PF04156.9 EXF82805.1 - 0.89 9.1 8.8 1.4 8.4 6.1 1.3 1 0 0 1 1 1 0 IncA protein DUF87 PF01935.12 EXF82805.1 - 6.2 6.5 8.6 2.9 7.6 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF87 S4 PF01479.20 EXF82806.1 - 1.6e-13 49.8 0.0 5.1e-13 48.2 0.0 1.9 2 0 0 2 2 2 1 S4 domain S4_2 PF13275.1 EXF82806.1 - 0.0018 17.8 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 S4 domain DUF4404 PF14357.1 EXF82806.1 - 0.35 11.3 0.1 0.35 11.3 0.1 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4404) La PF05383.12 EXF82807.1 - 1.8e-15 56.4 0.0 3.3e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EXF82807.1 - 8.1e-11 41.3 0.1 1.6e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF82807.1 - 2.2e-10 40.3 0.0 4.2e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF82807.1 - 1.1e-05 25.1 0.0 2.7e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EXF82807.1 - 0.12 12.2 1.7 0.36 10.6 0.0 2.5 2 0 0 2 2 2 0 RNA binding motif MFS_1 PF07690.11 EXF82808.1 - 3.5e-41 141.0 28.2 3.5e-41 141.0 19.5 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF82808.1 - 6.4e-10 38.1 7.0 6.4e-10 38.1 4.9 2.1 2 0 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EXF82808.1 - 3.7e-05 22.1 0.3 5.4e-05 21.5 0.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EXF82808.1 - 0.0061 14.6 0.2 0.015 13.3 0.1 1.6 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 EXF82808.1 - 0.28 9.2 5.0 3.4 5.6 3.5 2.0 1 1 0 1 1 1 0 Transmembrane secretion effector Clr5 PF14420.1 EXF82810.1 - 1.7e-11 43.8 0.6 3.8e-11 42.7 0.4 1.6 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.1 EXF82810.1 - 0.00043 20.1 1.3 0.056 13.3 0.1 3.0 1 1 2 3 3 3 2 Tetratricopeptide repeat PPR PF01535.15 EXF82810.1 - 0.071 13.1 0.2 3.3 7.9 0.0 3.0 3 0 0 3 3 3 0 PPR repeat TPR_19 PF14559.1 EXF82810.1 - 0.092 13.0 0.3 4.5 7.6 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EXF82810.1 - 0.11 13.1 0.2 60 4.6 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat Pro_dh PF01619.13 EXF82812.1 - 4.8e-40 137.4 0.0 6.4e-40 137.0 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase AP_endonuc_2 PF01261.19 EXF82812.1 - 0.02 14.1 0.0 0.044 13.0 0.0 1.5 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel AA_permease PF00324.16 EXF82813.1 - 2.8e-118 395.3 41.9 4.6e-117 391.2 29.0 1.9 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF82813.1 - 1.6e-39 135.6 37.0 9.6e-39 133.1 25.7 1.8 1 1 0 1 1 1 1 Amino acid permease Glyco_transf_22 PF03901.12 EXF82814.1 - 1.5e-76 258.1 16.7 8.8e-59 199.5 6.4 2.0 1 1 1 2 2 2 2 Alg9-like mannosyltransferase family PDR_assoc PF08370.6 EXF82814.1 - 7.8 6.0 8.1 11 5.6 0.6 2.7 2 0 0 2 2 2 0 Plant PDR ABC transporter associated UPF0121 PF03661.8 EXF82815.1 - 5.2e-10 38.9 2.7 7.8e-10 38.3 1.9 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) DSPc PF00782.15 EXF82816.1 - 3.3e-09 36.4 0.0 6.4e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EXF82816.1 - 0.00016 21.0 0.0 0.00033 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EXF82816.1 - 0.0049 17.1 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PAP1 PF08601.5 EXF82816.1 - 7.7 6.0 13.3 0.73 9.4 6.0 1.6 2 0 0 2 2 2 0 Transcription factor PAP1 Glucokinase PF02685.11 EXF82817.1 - 0.15 10.8 0.0 0.19 10.4 0.0 1.1 1 0 0 1 1 1 0 Glucokinase RicinB_lectin_2 PF14200.1 EXF82818.1 - 1.1e-07 32.1 0.1 2e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain-like CDtoxinA PF03498.9 EXF82818.1 - 0.0074 15.6 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Cytolethal distending toxin A/C family Ricin_B_lectin PF00652.17 EXF82818.1 - 0.017 15.1 0.7 0.3 11.1 0.4 2.4 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain Mid2 PF04478.7 EXF82818.1 - 0.023 14.1 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Adeno_E3_CR2 PF02439.10 EXF82818.1 - 0.023 14.2 0.8 0.056 12.9 0.5 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Linker_histone PF00538.14 EXF82819.1 - 1.2e-22 79.7 0.2 3.3e-22 78.3 0.1 1.8 1 0 0 1 1 1 1 linker histone H1 and H5 family Spot_14 PF07084.7 EXF82819.1 - 0.3 10.9 0.1 0.3 10.9 0.0 3.2 1 1 3 4 4 4 0 Thyroid hormone-inducible hepatic protein Spot 14 Asp-B-Hydro_N PF05279.6 EXF82819.1 - 4.2 7.1 31.2 5.4 6.7 21.6 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region FA_hydroxylase PF04116.8 EXF82822.1 - 1.6e-07 31.7 12.6 2.3e-06 27.9 9.5 2.1 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Glyco_transf_90 PF05686.7 EXF82823.1 - 1.3e-11 43.8 0.7 5.4e-10 38.5 0.5 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 90 MFS_1 PF07690.11 EXF82824.1 - 1.9e-30 105.7 29.9 1.9e-30 105.7 20.7 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2649 PF10854.3 EXF82824.1 - 0.2 11.7 4.0 0.17 12.0 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2649) SKG6 PF08693.5 EXF82825.1 - 0.016 14.5 0.9 0.016 14.5 0.6 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Metallophos_2 PF12850.2 EXF82827.1 - 9.3e-13 48.3 0.0 1.5e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EXF82827.1 - 1.2e-12 47.6 0.1 1.1e-11 44.4 0.1 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase NAD_binding_6 PF08030.7 EXF82828.1 - 2.7e-31 108.5 0.0 5.4e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EXF82828.1 - 6.9e-20 70.8 0.0 2.6e-19 69.0 0.0 2.0 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EXF82828.1 - 8.6e-16 58.1 9.3 8.6e-16 58.1 6.5 2.3 1 1 1 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EXF82828.1 - 0.0028 17.7 0.0 0.0073 16.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain UQ_con PF00179.21 EXF82829.1 - 2.7e-51 172.6 0.0 3.1e-51 172.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EXF82829.1 - 6.5e-05 22.6 0.0 7.8e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EXF82829.1 - 0.0052 16.6 0.0 0.0057 16.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EXF82829.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain Acyl-CoA_dh_N PF02771.11 EXF82830.1 - 7.7e-25 87.6 0.8 2e-24 86.3 0.5 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EXF82830.1 - 1.4e-22 80.3 0.1 2.5e-22 79.5 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EXF82830.1 - 2.8e-17 61.9 0.1 7.3e-17 60.6 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EXF82830.1 - 8.9e-08 32.4 0.1 1.6e-07 31.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ADK PF00406.17 EXF82832.1 - 9.2e-09 35.3 0.0 1.2e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase Thymidylate_kin PF02223.12 EXF82832.1 - 0.053 12.9 0.0 0.085 12.2 0.0 1.3 1 0 0 1 1 1 0 Thymidylate kinase Radical_SAM PF04055.16 EXF82833.1 - 2.9e-15 56.8 0.2 7.7e-15 55.4 0.2 1.8 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EXF82833.1 - 3e-07 30.6 0.2 6.8e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EXF82833.1 - 3.8e-06 26.9 0.0 8.6e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF3176 PF11374.3 EXF82834.1 - 3.8e-33 113.6 0.4 6.6e-33 112.8 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) SYS1 PF09801.4 EXF82835.1 - 2.6e-44 150.7 0.1 3e-44 150.5 0.1 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DctQ PF04290.7 EXF82835.1 - 3.4 7.4 11.5 1.8 8.3 3.9 2.1 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component TPPK_C PF12555.3 EXF82835.1 - 7.7 6.3 13.0 0.12 12.0 1.0 2.8 3 0 0 3 3 3 0 Thiamine pyrophosphokinase C terminal COX6B PF02297.12 EXF82836.1 - 1.4e-23 82.7 3.7 1.8e-23 82.2 2.6 1.2 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb IL28A PF15177.1 EXF82836.1 - 0.003 17.0 0.2 0.0049 16.3 0.1 1.4 1 1 0 1 1 1 1 Interleukin-28A PIP5K PF01504.13 EXF82837.1 - 2.1e-85 285.8 0.1 3.1e-85 285.3 0.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Fungal_trans PF04082.13 EXF82838.1 - 3.1e-05 22.9 0.4 0.00011 21.2 0.1 2.0 2 0 0 2 2 2 1 Fungal specific transcription factor domain p450 PF00067.17 EXF82839.1 - 6.1e-66 222.8 0.0 8.7e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Gti1_Pac2 PF09729.4 EXF82840.1 - 1.7e-49 167.9 2.0 3.9e-47 160.2 1.4 2.3 1 1 0 1 1 1 1 Gti1/Pac2 family SKG6 PF08693.5 EXF82841.1 - 0.066 12.5 2.5 0.13 11.6 1.7 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4448 PF14610.1 EXF82841.1 - 0.078 12.4 0.2 0.3 10.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF1777 PF08648.7 EXF82842.1 - 0.75 9.4 25.5 1.6 8.3 17.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) CAF-1_p150 PF11600.3 EXF82842.1 - 2.1 7.6 29.6 0.034 13.5 14.2 2.3 1 1 2 3 3 3 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Nucleocapsid-N PF11030.3 EXF82842.1 - 3.1 7.5 7.5 4.3 7.1 4.4 2.0 1 1 0 1 1 1 0 Nucleocapsid protein N DUF4355 PF14265.1 EXF82842.1 - 3.2 7.7 16.2 6.3 6.7 11.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) Amidase PF01425.16 EXF82843.1 - 1.2e-69 235.2 0.1 1.6e-69 234.8 0.0 1.1 1 0 0 1 1 1 1 Amidase PAS_3 PF08447.6 EXF82845.1 - 8.8e-12 44.9 0.0 2.5e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EXF82845.1 - 3.6e-11 43.3 0.0 9.2e-11 42.0 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EXF82845.1 - 4.6e-07 29.6 0.1 1.2e-06 28.2 0.0 1.7 2 0 0 2 2 2 1 PAS fold PAS_11 PF14598.1 EXF82845.1 - 0.00024 21.0 0.0 0.00055 19.8 0.0 1.5 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 EXF82845.1 - 0.00061 19.8 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold DUF4428 PF14471.1 EXF82845.1 - 0.018 14.7 2.4 0.045 13.5 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) APC2 PF08672.6 EXF82845.1 - 0.046 13.9 0.0 23 5.3 0.0 3.0 3 0 0 3 3 3 0 Anaphase promoting complex (APC) subunit 2 SelB-wing_2 PF09106.6 EXF82845.1 - 0.11 12.4 0.4 4 7.4 0.0 2.5 2 0 0 2 2 2 0 Elongation factor SelB, winged helix AAA_23 PF13476.1 EXF82846.1 - 2.2e-27 96.6 0.2 2.2e-27 96.6 0.1 6.9 1 1 2 3 3 3 1 AAA domain SbcCD_C PF13558.1 EXF82846.1 - 5e-12 45.5 0.0 1.8e-11 43.7 0.0 2.1 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 EXF82846.1 - 1.8e-07 30.0 20.6 1.7e-05 23.5 11.9 6.5 2 1 5 7 7 7 4 AAA domain AAA_21 PF13304.1 EXF82846.1 - 1.4e-06 28.5 4.8 4.7e-05 23.5 2.2 4.3 5 1 0 5 5 5 2 AAA domain AAA_29 PF13555.1 EXF82846.1 - 0.0023 17.4 0.0 0.0047 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EXF82846.1 - 0.091 13.0 0.0 0.091 13.0 0.0 6.4 3 2 0 3 3 3 0 ABC transporter AAA_16 PF13191.1 EXF82846.1 - 0.22 11.4 0.0 0.22 11.4 0.0 5.7 5 2 0 5 5 5 0 AAA ATPase domain SMC_N PF02463.14 EXF82846.1 - 0.69 9.1 63.7 7 5.8 44.2 2.6 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain PPP4R2 PF09184.6 EXF82847.1 - 1.4e-11 44.5 0.0 1.4e-11 44.5 0.0 4.1 3 1 1 4 4 4 2 PPP4R2 RRF PF01765.14 EXF82848.1 - 4.5e-18 65.2 4.2 6.1e-18 64.8 2.9 1.2 1 0 0 1 1 1 1 Ribosome recycling factor IFT57 PF10498.4 EXF82848.1 - 0.0088 14.8 3.5 0.012 14.4 2.4 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 HATPase_c PF02518.21 EXF82850.1 - 2.1e-23 82.1 0.1 3.6e-23 81.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EXF82850.1 - 2.2e-20 72.7 0.0 4.6e-20 71.6 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain PAS_9 PF13426.1 EXF82850.1 - 2.6e-10 40.6 0.1 1.8e-07 31.4 0.0 2.6 2 0 0 2 2 2 2 PAS domain HisKA PF00512.20 EXF82850.1 - 5.3e-08 32.7 0.1 1.4e-07 31.3 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.5 EXF82850.1 - 1.6e-06 28.1 0.0 0.0046 16.9 0.0 2.8 2 0 0 2 2 2 2 PAS fold GAF_2 PF13185.1 EXF82850.1 - 2.5e-06 28.0 0.0 0.0039 17.6 0.0 2.8 2 0 0 2 2 2 2 GAF domain PAS PF00989.19 EXF82850.1 - 7.6e-05 22.4 0.1 0.00059 19.6 0.0 2.4 2 0 0 2 2 2 1 PAS fold GAF_3 PF13492.1 EXF82850.1 - 0.0011 19.0 0.0 0.0075 16.3 0.0 2.3 2 0 0 2 2 2 1 GAF domain DEAD PF00270.24 EXF82853.1 - 2.5e-24 85.6 0.0 8.5e-14 51.3 0.0 2.5 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF82853.1 - 1.8e-22 78.9 0.1 6.2e-22 77.2 0.1 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EXF82853.1 - 0.00034 20.4 1.0 0.00062 19.6 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit TFIIA PF03153.8 EXF82853.1 - 0.00042 20.3 8.3 0.00081 19.3 5.8 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Sigma70_ner PF04546.8 EXF82853.1 - 0.016 14.7 16.2 0.021 14.4 2.8 2.4 2 0 0 2 2 2 0 Sigma-70, non-essential region CENP-B_dimeris PF09026.5 EXF82853.1 - 2.7 8.2 15.3 0.04 14.1 5.2 2.0 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NOA36 PF06524.7 EXF82853.1 - 2.9 7.0 8.8 5.5 6.1 6.1 1.4 1 0 0 1 1 1 0 NOA36 protein RXT2_N PF08595.6 EXF82853.1 - 3.9 7.2 11.6 0.3 10.8 2.6 2.7 3 0 0 3 3 3 0 RXT2-like, N-terminal DUF2457 PF10446.4 EXF82853.1 - 4.6 5.8 23.7 0.016 13.9 7.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) PH_6 PF15406.1 EXF82854.1 - 1.4e-47 160.3 5.4 1.4e-47 160.3 3.7 2.9 2 0 0 2 2 2 1 Pleckstrin homology domain PH PF00169.24 EXF82854.1 - 0.0064 16.6 0.0 0.021 15.0 0.0 1.9 1 0 0 1 1 1 1 PH domain tRNA-synt_2 PF00152.15 EXF82856.1 - 1.4e-68 231.1 0.0 1.9e-68 230.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EXF82856.1 - 5.4e-09 35.7 0.0 9.1e-09 35.0 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EXF82856.1 - 5.3e-05 22.5 0.0 0.022 13.9 0.0 2.4 2 1 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EXF82856.1 - 0.057 13.0 0.0 9.2 5.8 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) zf-Tim10_DDP PF02953.10 EXF82857.1 - 2.8e-21 74.5 2.5 3.4e-21 74.3 1.7 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF2897 PF11446.3 EXF82858.1 - 0.03 14.1 0.3 0.12 12.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) DUF2681 PF10883.3 EXF82858.1 - 1.5 9.0 0.0 1.5 9.0 0.0 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF2681) CLTH PF10607.4 EXF82859.1 - 7.2e-29 100.3 0.0 1.9e-28 99.0 0.0 1.7 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EXF82859.1 - 1.7e-20 72.4 4.0 3.9e-20 71.2 2.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EXF82859.1 - 4.8e-07 29.3 2.2 8e-07 28.6 1.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EXF82859.1 - 3.2e-06 26.8 2.4 5.6e-06 26.0 1.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EXF82859.1 - 1.7e-05 24.7 3.3 3.1e-05 23.8 2.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EXF82859.1 - 1.9e-05 24.2 1.5 3.3e-05 23.4 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EXF82859.1 - 0.00031 20.0 0.1 0.00051 19.3 0.1 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4 PF00097.20 EXF82859.1 - 0.00032 20.2 3.5 0.00059 19.4 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EXF82859.1 - 0.0016 18.2 3.7 0.0037 17.1 2.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EXF82859.1 - 0.065 12.8 2.1 0.12 12.0 1.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EXF82859.1 - 0.088 12.3 1.2 0.2 11.2 0.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-MIZ PF02891.15 EXF82859.1 - 0.16 11.4 2.4 0.31 10.5 1.7 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Myosin_tail_1 PF01576.14 EXF82860.1 - 0.04 11.6 6.5 0.06 11.0 4.5 1.2 1 0 0 1 1 1 0 Myosin tail AAA_13 PF13166.1 EXF82860.1 - 0.056 11.9 5.1 0.087 11.2 3.6 1.1 1 0 0 1 1 1 0 AAA domain CENP-Q PF13094.1 EXF82860.1 - 0.099 12.6 8.8 6.3 6.7 3.7 3.2 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit PG_binding_1 PF01471.13 EXF82860.1 - 0.1 12.5 0.0 17 5.4 0.0 3.1 2 0 0 2 2 2 0 Putative peptidoglycan binding domain Laminin_II PF06009.7 EXF82860.1 - 0.19 11.4 2.9 2.6 7.7 0.4 2.8 1 1 2 3 3 3 0 Laminin Domain II Sugar_tr PF00083.19 EXF82861.1 - 1.1e-45 156.0 4.1 1.4e-45 155.7 2.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF82861.1 - 4.3e-21 75.0 6.3 4.8e-21 74.8 4.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EXF82861.1 - 9.3e-06 24.1 0.4 1.1e-05 23.8 0.2 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EXF82861.1 - 0.0026 16.2 1.1 0.0039 15.6 0.4 1.4 1 1 0 1 1 1 1 MFS/sugar transport protein DUF791 PF05631.9 EXF82861.1 - 0.0027 16.4 1.3 0.004 15.9 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF791) Phage_holin_2 PF04550.7 EXF82861.1 - 0.27 11.3 2.3 2.1 8.4 0.3 2.4 1 1 0 2 2 2 0 Phage holin family 2 Transgly_assoc PF04226.8 EXF82861.1 - 0.62 10.1 9.7 0.074 13.1 1.9 2.7 2 0 0 2 2 2 0 Transglycosylase associated protein HET PF06985.6 EXF82862.1 - 6.3e-36 123.5 0.9 1.2e-35 122.6 0.3 1.8 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) FAD_binding_3 PF01494.14 EXF82863.1 - 6.1e-28 97.8 0.0 5.7e-17 61.7 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain Trp_halogenase PF04820.9 EXF82863.1 - 1e-06 27.7 3.6 0.027 13.0 0.3 3.1 2 1 1 3 3 3 3 Tryptophan halogenase DAO PF01266.19 EXF82863.1 - 4.9e-06 25.6 0.4 0.044 12.6 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.9 EXF82863.1 - 9.9e-06 24.2 0.1 0.0019 16.7 0.0 2.2 2 0 0 2 2 2 2 HI0933-like protein Lycopene_cycl PF05834.7 EXF82863.1 - 2.3e-05 23.5 0.2 0.15 10.9 0.0 2.5 3 0 0 3 3 3 2 Lycopene cyclase protein SE PF08491.5 EXF82863.1 - 0.00022 20.1 0.0 0.0063 15.3 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase Pyr_redox_3 PF13738.1 EXF82863.1 - 0.00022 21.3 0.0 0.00055 20.0 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF82863.1 - 0.00064 19.6 0.8 0.0023 17.8 0.5 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF82863.1 - 0.0022 17.9 0.1 0.0044 17.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EXF82863.1 - 0.0031 16.6 0.0 0.046 12.7 0.0 2.3 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EXF82863.1 - 0.012 16.0 0.1 7.2 7.0 0.0 2.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF82863.1 - 0.013 14.3 0.1 0.019 13.8 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EXF82863.1 - 0.023 13.5 1.4 0.057 12.2 0.6 1.8 1 1 1 2 2 2 0 FAD binding domain FAD_oxidored PF12831.2 EXF82863.1 - 0.039 13.0 1.8 0.048 12.7 0.5 1.7 2 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EXF82863.1 - 0.13 12.0 1.2 1.9 8.2 0.2 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding F_bP_aldolase PF01116.15 EXF82864.1 - 2.4e-83 279.5 0.1 2.7e-83 279.3 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II NAD_binding_11 PF14833.1 EXF82865.1 - 7.4e-37 126.1 0.1 1.4e-23 83.2 0.0 2.4 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase NAD_binding_2 PF03446.10 EXF82865.1 - 6.1e-33 113.9 0.8 1.1e-32 113.1 0.6 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EXF82865.1 - 3e-05 24.3 0.5 0.00041 20.7 0.1 2.9 2 1 1 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EXF82865.1 - 0.0052 16.4 0.2 0.022 14.3 0.2 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2-Hacid_dh_C PF02826.14 EXF82865.1 - 0.03 13.4 0.0 0.053 12.6 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EXF82865.1 - 0.085 12.2 0.0 13 5.0 0.0 2.5 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain YL1 PF05764.8 EXF82866.1 - 0.005 16.4 2.0 0.0052 16.4 1.4 1.1 1 0 0 1 1 1 1 YL1 nuclear protein Herpes_DNAp_acc PF04929.7 EXF82866.1 - 0.07 12.0 3.6 0.089 11.7 2.5 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor GAGA_bind PF06217.7 EXF82866.1 - 0.077 12.9 0.8 0.091 12.7 0.6 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family PBP1_TM PF14812.1 EXF82866.1 - 0.84 9.9 5.6 1.4 9.2 3.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Epimerase PF01370.16 EXF82867.1 - 2e-08 33.9 0.0 3.5e-08 33.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EXF82867.1 - 0.00021 20.2 0.0 0.35 9.7 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EXF82867.1 - 0.019 13.7 0.2 0.05 12.3 0.1 1.8 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Acetyltransf_1 PF00583.19 EXF82869.1 - 8.1e-10 38.6 1.1 1.3e-09 37.9 0.1 1.9 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF82869.1 - 1.9e-09 37.5 0.0 7.5e-09 35.6 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EXF82869.1 - 7.6e-06 25.8 0.0 3.2e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EXF82869.1 - 2.9e-05 24.1 0.0 0.0053 16.8 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EXF82869.1 - 3e-05 23.6 0.0 6.1e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 EXF82869.1 - 0.0071 16.2 0.0 0.22 11.4 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EXF82869.1 - 0.041 13.7 0.0 0.18 11.6 0.0 2.1 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase DUF3669 PF12417.3 EXF82870.1 - 2.8e-21 75.0 0.1 7.4e-21 73.6 0.1 1.7 1 0 0 1 1 1 1 Zinc finger protein TRI12 PF06609.8 EXF82871.1 - 4.1e-50 170.5 23.9 5.4e-50 170.1 16.5 1.0 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_1 PF07690.11 EXF82871.1 - 6.9e-26 90.7 58.2 6.1e-24 84.3 40.2 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF82871.1 - 1.1e-07 30.7 15.9 1.1e-07 30.7 11.0 4.0 4 0 0 4 4 4 1 Sugar (and other) transporter SKG6 PF08693.5 EXF82872.1 - 9.5e-08 31.2 0.1 1.8e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain RicinB_lectin_2 PF14200.1 EXF82872.1 - 1.3e-07 31.9 1.3 1e-06 29.0 0.2 2.3 1 1 1 2 2 2 1 Ricin-type beta-trefoil lectin domain-like VSP PF03302.8 EXF82872.1 - 0.016 13.8 5.3 0.025 13.2 3.6 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Rax2 PF12768.2 EXF82872.1 - 0.02 14.0 0.0 0.033 13.3 0.0 1.3 1 0 0 1 1 1 0 Cortical protein marker for cell polarity DUF2012 PF09430.5 EXF82872.1 - 0.022 14.5 0.0 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2012) DUF4448 PF14610.1 EXF82872.1 - 0.028 13.9 0.0 0.047 13.1 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) Botulinum_HA-17 PF05588.6 EXF82872.1 - 0.061 13.2 0.0 0.098 12.5 0.0 1.2 1 0 0 1 1 1 0 Clostridium botulinum HA-17 protein GDE_C PF06202.9 EXF82874.1 - 1.3e-07 30.6 0.5 2.2e-07 29.9 0.3 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Na_H_Exchanger PF00999.16 EXF82876.1 - 1e-34 119.7 12.5 1.3e-34 119.3 8.6 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family YrhC PF14143.1 EXF82876.1 - 0.033 14.1 2.4 0.064 13.2 0.0 2.7 2 0 0 2 2 2 0 YrhC-like protein MpPF26 PF07666.6 EXF82876.1 - 0.071 13.0 2.8 0.36 10.7 0.1 2.7 2 0 0 2 2 2 0 M penetrans paralogue family 26 Ank_2 PF12796.2 EXF82877.1 - 5.8e-54 180.4 0.9 1e-19 70.6 0.1 5.7 3 2 2 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EXF82877.1 - 3.4e-50 165.4 4.6 9.5e-09 34.6 0.0 11.1 13 0 0 13 13 13 8 Ankyrin repeat Ank_4 PF13637.1 EXF82877.1 - 2.8e-37 126.4 7.2 2.1e-09 37.6 0.0 9.1 3 2 5 9 9 9 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF82877.1 - 2.5e-32 107.7 5.2 3.3e-06 26.8 0.0 10.0 10 0 0 10 10 10 5 Ankyrin repeat Ank_5 PF13857.1 EXF82877.1 - 4.4e-26 90.3 3.4 1.4e-05 25.1 0.0 7.3 5 3 2 7 7 7 6 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 EXF82877.1 - 4.2e-11 42.2 0.0 9.5e-11 41.1 0.0 1.6 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 EXF82877.1 - 0.00095 18.8 0.0 0.0026 17.4 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EXF82877.1 - 0.035 14.2 0.0 0.18 11.9 0.0 2.2 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EXF82877.1 - 0.065 13.2 0.1 0.47 10.4 0.0 2.5 2 1 0 2 2 2 0 AAA ATPase domain DUF1049 PF06305.6 EXF82878.1 - 0.0013 18.1 0.4 0.003 16.9 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1049) DUF1308 PF07000.6 EXF82879.1 - 2.8e-48 164.4 0.0 5.3e-48 163.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1308) DUF1688 PF07958.6 EXF82880.1 - 2.4e-175 583.0 0.0 2.9e-175 582.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1688) 60KD_IMP PF02096.15 EXF82882.1 - 1e-38 133.0 1.4 1.5e-38 132.4 0.9 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein FAP PF07174.6 EXF82882.1 - 5.3 6.2 27.2 1.7 7.8 12.5 2.2 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) TOM13 PF08219.6 EXF82883.1 - 6.7e-31 105.8 0.0 8.4e-31 105.5 0.0 1.1 1 0 0 1 1 1 1 Outer membrane protein TOM13 SEP PF08059.8 EXF82884.1 - 1.2e-25 89.6 0.0 2.1e-25 88.7 0.0 1.4 1 0 0 1 1 1 1 SEP domain UBX PF00789.15 EXF82884.1 - 2e-11 43.7 0.0 3.1e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.1 EXF82884.1 - 3.6e-10 39.2 0.0 5.9e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 EXF82884.1 - 0.14 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain DUF2457 PF10446.4 EXF82884.1 - 2.1 6.9 7.3 3.6 6.2 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Gtr1_RagA PF04670.7 EXF82885.1 - 7.5e-93 309.9 0.0 9.8e-93 309.5 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EXF82885.1 - 1.1e-07 31.3 0.0 2.2e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EXF82885.1 - 1.9e-06 27.2 0.0 3e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EXF82885.1 - 1.9e-05 24.6 0.0 3.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EXF82885.1 - 0.00014 22.3 0.0 0.00028 21.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein AAA_29 PF13555.1 EXF82885.1 - 0.00089 18.7 1.0 0.0068 15.9 0.2 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EXF82885.1 - 0.0029 17.8 0.1 0.013 15.7 0.0 2.0 2 1 0 2 2 2 1 ABC transporter DUF815 PF05673.8 EXF82885.1 - 0.019 13.8 0.0 0.042 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) G-alpha PF00503.15 EXF82885.1 - 0.034 12.8 0.4 0.86 8.2 0.1 2.3 2 0 0 2 2 2 0 G-protein alpha subunit DUF258 PF03193.11 EXF82885.1 - 0.064 12.4 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 zf-C2H2_4 PF13894.1 EXF82886.1 - 0.048 14.0 5.8 0.17 12.2 0.5 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF82886.1 - 0.46 10.9 6.4 1.1 9.7 0.3 3.8 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF1295 PF06966.7 EXF82887.1 - 3.9e-31 108.1 0.1 5.7e-31 107.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EXF82887.1 - 0.00037 20.6 0.0 0.00075 19.6 0.0 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.11 EXF82887.1 - 0.0014 18.3 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase MT0933_antitox PF14013.1 EXF82887.1 - 0.002 18.1 2.4 0.043 13.9 0.7 3.2 2 1 0 2 2 2 1 MT0933-like antitoxin protein Adeno_PIX PF03955.9 EXF82887.1 - 0.0035 17.8 4.1 0.79 10.2 0.0 4.8 3 1 3 6 6 6 1 Adenovirus hexon-associated protein (IX) DUF2062 PF09835.4 EXF82887.1 - 0.015 14.8 0.5 0.47 10.0 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) PEMT PF04191.8 EXF82887.1 - 0.021 14.9 0.0 0.047 13.7 0.0 1.6 1 0 0 1 1 1 0 Phospholipid methyltransferase ERG4_ERG24 PF01222.12 EXF82887.1 - 0.12 10.8 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Ergosterol biosynthesis ERG4/ERG24 family Dehydrin PF00257.14 EXF82887.1 - 3 8.1 11.6 27 5.0 6.4 3.5 1 1 1 2 2 2 0 Dehydrin AA_permease_2 PF13520.1 EXF82889.1 - 4.9e-56 190.0 46.8 5.7e-56 189.8 32.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF82889.1 - 1.8e-23 82.6 39.1 2.4e-23 82.2 27.1 1.0 1 0 0 1 1 1 1 Amino acid permease Glucosamine_iso PF01182.15 EXF82890.1 - 8.2e-27 94.2 0.0 1.3e-26 93.5 0.0 1.3 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase FAD_binding_8 PF08022.7 EXF82890.1 - 0.035 13.9 0.0 0.066 13.0 0.0 1.4 1 0 0 1 1 1 0 FAD-binding domain Hexokinase_2 PF03727.11 EXF82892.1 - 1.2e-61 208.0 0.0 2.2e-47 161.3 0.0 2.2 2 0 0 2 2 2 2 Hexokinase Hexokinase_1 PF00349.16 EXF82892.1 - 9.9e-53 178.5 0.0 1.7e-52 177.7 0.0 1.4 1 0 0 1 1 1 1 Hexokinase Serglycin PF04360.7 EXF82893.1 - 8 6.1 8.5 0.43 10.3 1.3 2.2 3 0 0 3 3 3 0 Serglycin Alginate_lyase PF05426.7 EXF82894.1 - 1.2e-07 31.4 4.3 7.3e-07 28.8 2.9 2.0 1 1 0 1 1 1 1 Alginate lyase Alginate_lyase PF05426.7 EXF82895.1 - 1.6e-10 40.7 7.3 4.3e-10 39.4 5.0 1.6 1 1 0 1 1 1 1 Alginate lyase Amino_oxidase PF01593.19 EXF82896.1 - 3.8e-29 102.0 0.0 6.6e-29 101.2 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EXF82896.1 - 6.5e-09 35.6 0.0 2e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EXF82896.1 - 0.00016 22.0 0.2 0.0017 18.7 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF82896.1 - 0.00096 18.1 4.0 0.0044 15.9 0.5 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Rossmann-like PF10727.4 EXF82896.1 - 0.11 12.1 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Rossmann-like domain Amidase PF01425.16 EXF82897.1 - 5.1e-29 101.3 0.3 3.6e-28 98.6 0.1 1.9 2 0 0 2 2 2 1 Amidase Epimerase PF01370.16 EXF82898.1 - 1.8e-10 40.6 0.1 6.2e-10 38.9 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF82898.1 - 1.7e-06 28.1 0.0 2.6e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EXF82898.1 - 5.2e-06 25.8 0.2 2.3e-05 23.7 0.0 1.9 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EXF82898.1 - 0.0013 18.7 0.1 0.0032 17.4 0.0 1.7 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EXF82898.1 - 0.017 14.0 0.0 2.7 6.8 0.0 2.1 2 0 0 2 2 2 0 RmlD substrate binding domain Cu_bind_like PF02298.12 EXF82899.1 - 0.016 15.0 0.1 0.031 14.0 0.0 1.5 1 1 0 1 1 1 0 Plastocyanin-like domain ADH_N PF08240.7 EXF82900.1 - 1.5e-09 37.5 0.0 2.5e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF82900.1 - 7.1e-06 25.5 0.0 1.5e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.16 EXF82900.1 - 0.029 13.8 0.0 0.041 13.3 0.0 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EXF82901.1 - 2.9e-20 72.5 0.0 4.2e-20 72.0 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF82901.1 - 6.9e-18 65.2 0.0 1.4e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF82901.1 - 1.5e-06 27.8 1.0 0.00043 19.8 0.3 2.8 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EXF82901.1 - 0.0026 16.7 0.3 0.0087 14.9 0.0 1.8 2 0 0 2 2 2 1 RmlD substrate binding domain F420_oxidored PF03807.12 EXF82901.1 - 0.0065 16.8 0.1 0.014 15.7 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent TrkA_N PF02254.13 EXF82901.1 - 0.0087 16.0 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Methyltransf_25 PF13649.1 EXF82901.1 - 0.044 14.1 0.1 0.14 12.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain DapB_N PF01113.15 EXF82901.1 - 0.047 13.5 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 EXF82901.1 - 0.066 13.1 0.5 0.12 12.2 0.3 1.3 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.14 EXF82901.1 - 0.068 11.8 0.0 0.1 11.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.19 EXF82901.1 - 0.13 12.6 0.1 0.32 11.3 0.0 1.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain HhH-GPD PF00730.20 EXF82907.1 - 2.8e-08 33.9 0.0 6.2e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein zf-PHD-like PF15446.1 EXF82907.1 - 0.032 13.5 0.4 0.032 13.5 0.3 2.4 2 1 0 2 2 2 0 PHD/FYVE-zinc-finger like domain HHH PF00633.18 EXF82907.1 - 0.065 12.9 0.0 0.21 11.3 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix motif Sugar_tr PF00083.19 EXF82908.1 - 4.4e-56 190.3 19.5 5.4e-56 190.0 13.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF82908.1 - 2.6e-19 69.1 34.3 1.4e-17 63.4 11.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EXF82908.1 - 2.4e-05 22.9 24.5 0.0062 14.9 7.2 3.3 2 2 1 3 3 3 3 MFS/sugar transport protein MFS_1_like PF12832.2 EXF82908.1 - 0.058 13.1 4.9 3.2 7.5 0.4 3.5 4 0 0 4 4 4 0 MFS_1 like family MFS_1 PF07690.11 EXF82909.1 - 6e-49 166.6 50.3 6e-49 166.6 34.8 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EXF82909.1 - 5.2e-20 71.1 20.4 6.3e-18 64.2 13.4 2.3 2 1 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EXF82909.1 - 8.7e-18 64.1 24.6 1.9e-17 62.9 5.1 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Kinocilin PF15033.1 EXF82909.1 - 0.37 10.3 8.0 0.67 9.4 0.2 3.3 4 0 0 4 4 4 0 Kinocilin protein COesterase PF00135.23 EXF82910.1 - 1.3e-68 232.0 0.0 1.8e-68 231.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF82910.1 - 6.9e-13 48.6 0.3 6.7e-12 45.4 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF82910.1 - 5e-06 26.3 1.7 1.8e-05 24.5 0.2 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.15 EXF82910.1 - 0.00044 19.7 0.7 0.0012 18.2 0.5 1.6 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 EXF82910.1 - 0.00044 20.1 1.7 0.00081 19.3 0.8 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF82910.1 - 0.0089 15.2 0.1 0.019 14.1 0.1 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Fungal_trans PF04082.13 EXF82911.1 - 1.1e-11 44.1 0.0 2.3e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF82911.1 - 0.00011 21.9 5.2 0.00018 21.3 3.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain VWA_3 PF13768.1 EXF82912.1 - 8.1e-26 90.5 0.0 1.6e-25 89.5 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 EXF82912.1 - 8.7e-21 73.8 0.0 1.8e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_2 PF13519.1 EXF82912.1 - 2.2e-10 40.9 0.0 4.6e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Nucleoporin_FG PF13634.1 EXF82912.1 - 4.4e-10 39.7 71.1 2.2e+02 2.0 0.0 4.6 2 1 0 2 2 2 0 Nucleoporin FG repeat region VIT_2 PF13757.1 EXF82912.1 - 1.9e-07 30.4 0.1 4.4e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 EXF82912.1 - 3.5e-07 30.0 0.0 6.8e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 EXF82912.1 - 0.027 13.6 0.0 0.062 12.4 0.0 1.5 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein DUF1655 PF07868.6 EXF82912.1 - 0.33 10.9 0.5 0.81 9.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1655) Acetyltransf_1 PF00583.19 EXF82913.1 - 1.7e-10 40.8 0.0 1.4e-09 37.8 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF82913.1 - 0.00036 20.6 0.0 0.00054 20.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EXF82913.1 - 0.011 15.4 0.1 0.037 13.7 0.0 1.8 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_8 PF13523.1 EXF82913.1 - 0.028 14.3 0.0 0.066 13.0 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EXF82913.1 - 0.028 14.6 0.0 0.072 13.2 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EXF82913.1 - 0.049 13.7 0.0 0.15 12.2 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EXF82913.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase FAD-oxidase_C PF02913.14 EXF82914.1 - 6.3e-58 196.0 0.1 8.9e-58 195.5 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EXF82914.1 - 3.3e-38 130.3 0.0 7.1e-38 129.2 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain SLA_LP_auto_ag PF05889.8 EXF82914.1 - 0.0085 14.5 0.1 0.013 13.9 0.0 1.2 1 0 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) EHN PF06441.7 EXF82916.1 - 1.7e-32 111.6 0.3 2.6e-32 111.0 0.2 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EXF82916.1 - 1.9e-08 34.5 0.2 5.3e-07 29.7 0.2 2.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF82916.1 - 0.0033 16.9 0.1 0.014 14.9 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF82916.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family adh_short PF00106.20 EXF82918.1 - 3.8e-16 59.4 0.2 7.9e-16 58.4 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF82918.1 - 1.8e-07 31.2 0.0 3.6e-07 30.1 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EXF82918.1 - 0.0001 21.8 0.0 0.00013 21.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EXF82918.1 - 0.00011 21.8 0.4 0.00046 19.9 0.0 2.0 2 1 0 2 2 2 1 KR domain Eno-Rase_NADH_b PF12242.3 EXF82918.1 - 0.004 16.9 0.1 0.0085 15.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase zf-C3HC4_2 PF13923.1 EXF82919.1 - 0.02 14.9 6.4 0.033 14.1 4.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ZZ PF00569.12 EXF82919.1 - 0.058 12.9 6.4 0.096 12.2 4.5 1.3 1 0 0 1 1 1 0 Zinc finger, ZZ type DUF72 PF01904.13 EXF82919.1 - 0.07 12.8 0.0 0.078 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function DUF72 zf-C3HC4_3 PF13920.1 EXF82919.1 - 0.61 9.8 6.4 1.3 8.7 4.5 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zinc-ribbons_6 PF07191.7 EXF82919.1 - 0.67 9.7 6.1 8.3 6.2 4.3 2.1 1 1 0 1 1 1 0 zinc-ribbons Patatin PF01734.17 EXF82920.1 - 4.1e-23 82.3 0.0 6.8e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase zf-C3HC4_2 PF13923.1 EXF82920.1 - 0.00065 19.6 4.5 0.0018 18.2 3.0 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EXF82920.1 - 0.011 15.4 5.9 0.05 13.2 3.7 2.2 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EXF82920.1 - 0.044 13.6 5.0 0.11 12.4 0.4 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EXF82920.1 - 0.045 13.5 6.7 0.11 12.3 4.7 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 EXF82920.1 - 0.077 12.7 6.5 0.23 11.2 4.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain DUF1770 PF08589.5 EXF82920.1 - 0.15 12.7 0.8 0.3 11.7 0.1 1.8 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1770) DUF1275 PF06912.6 EXF82921.1 - 1.9e-39 135.0 14.6 2.3e-39 134.7 10.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1275) Cupin_1 PF00190.17 EXF82922.1 - 2.9e-29 101.3 0.0 1.3e-15 57.0 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EXF82922.1 - 2.5e-26 90.9 0.6 5.3e-13 48.2 0.1 2.3 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EXF82922.1 - 3.3e-09 35.9 0.0 0.0004 19.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EXF82922.1 - 2.6e-07 30.4 0.2 0.00055 19.6 0.0 2.4 2 0 0 2 2 2 2 AraC-like ligand binding domain MannoseP_isomer PF01050.13 EXF82922.1 - 0.00031 20.3 0.0 0.031 13.8 0.0 2.2 2 0 0 2 2 2 1 Mannose-6-phosphate isomerase ARD PF03079.9 EXF82922.1 - 0.0056 16.6 0.3 1.1 9.1 0.0 2.4 2 0 0 2 2 2 2 ARD/ARD' family 3-HAO PF06052.7 EXF82922.1 - 0.012 15.0 0.0 0.087 12.2 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyanthranilic acid dioxygenase GPI PF06560.6 EXF82922.1 - 0.048 12.6 0.0 0.082 11.9 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) DUF3140 PF11338.3 EXF82923.1 - 5.6e-31 106.5 2.0 5.6e-31 106.5 1.4 3.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3140) CDC27 PF09507.5 EXF82923.1 - 0.14 11.3 43.5 0.19 10.9 30.2 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Macoilin PF09726.4 EXF82923.1 - 9.5 4.3 28.2 11 4.1 19.6 1.1 1 0 0 1 1 1 0 Transmembrane protein Lipocalin_2 PF08212.7 EXF82924.1 - 3.2e-19 69.1 0.0 3.9e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.18 EXF82924.1 - 0.0028 17.6 0.0 0.011 15.6 0.0 1.8 1 1 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family Isochorismatase PF00857.15 EXF82925.1 - 6.5e-39 133.6 0.0 7.4e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Peptidase_M28 PF04389.12 EXF82926.1 - 1.5e-24 86.6 0.1 6.2e-24 84.7 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 EXF82926.1 - 2.3e-08 33.7 0.1 3.8e-08 33.0 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Cnl2_NKP2 PF09447.5 EXF82926.1 - 0.016 14.8 0.2 0.038 13.6 0.0 1.7 2 0 0 2 2 2 0 Cnl2/NKP2 family protein Bac_rhamnosid PF05592.6 EXF82927.1 - 2.2e-182 606.8 0.0 2.7e-182 606.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 EXF82927.1 - 3.4e-50 169.9 0.0 6.1e-50 169.1 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain Fungal_trans_2 PF11951.3 EXF82928.1 - 6.4e-16 57.9 1.4 6.4e-16 57.9 0.9 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain SelP_N PF04592.9 EXF82928.1 - 0.11 11.7 5.9 0.21 10.9 4.1 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Corona_nucleoca PF00937.13 EXF82928.1 - 1 8.2 10.0 1.5 7.7 6.9 1.1 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Pex14_N PF04695.8 EXF82928.1 - 4.4 7.3 9.2 8.9 6.3 6.4 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Aldo_ket_red PF00248.16 EXF82930.1 - 2.2e-53 180.9 0.0 2.6e-53 180.7 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.7 EXF82931.1 - 2.3e-29 101.3 2.9 4.3e-29 100.4 2.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF82931.1 - 1.6e-12 47.0 0.0 2.8e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Pyr_redox_3 PF13738.1 EXF82931.1 - 0.043 13.8 0.2 0.1 12.6 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_4 PF01565.18 EXF82934.1 - 4.6e-20 71.5 0.5 1e-19 70.3 0.3 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF82934.1 - 3.1e-09 36.6 0.0 7.7e-09 35.3 0.0 1.8 1 0 0 1 1 1 1 Berberine and berberine like Peptidase_M43 PF05572.8 EXF82935.1 - 3.5e-14 52.6 0.1 6.7e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 EXF82935.1 - 6.4e-07 29.9 0.1 1e-06 29.2 0.1 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EXF82935.1 - 1.3e-05 25.2 0.3 2e-05 24.5 0.2 1.4 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EXF82935.1 - 3.4e-05 23.9 0.7 5.5e-05 23.2 0.5 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EXF82935.1 - 0.00016 21.2 0.1 0.0002 20.9 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EXF82935.1 - 0.0088 15.7 0.8 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 Matrixin Peptidase_M57 PF12388.3 EXF82935.1 - 0.2 10.9 0.7 0.35 10.1 0.5 1.3 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase TPR_12 PF13424.1 EXF82936.1 - 4.8e-05 23.1 1.0 0.037 13.9 0.7 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 EXF82936.1 - 0.013 15.6 0.4 0.95 9.6 0.1 2.6 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EXF82936.1 - 0.11 12.1 0.1 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 TPR repeat CAF1A PF12253.3 EXF82941.1 - 2.2e-18 66.1 3.7 2.2e-18 66.1 2.6 3.3 2 1 0 2 2 1 1 Chromatin assembly factor 1 subunit A UPF0547 PF10571.4 EXF82941.1 - 0.086 12.5 0.9 0.15 11.7 0.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 TerY-C PF15616.1 EXF82941.1 - 0.21 11.5 0.0 0.21 11.5 0.0 2.1 2 0 0 2 2 1 0 TerY-C metal binding domain SprA-related PF12118.3 EXF82941.1 - 0.32 10.2 34.7 0.014 14.7 19.5 1.9 2 0 0 2 2 2 0 SprA-related family SAPS PF04499.10 EXF82941.1 - 0.34 9.5 13.6 0.62 8.6 9.4 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MIP-T3 PF10243.4 EXF82941.1 - 0.64 8.4 48.6 0.0074 14.8 26.3 2.3 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 EXF82941.1 - 0.89 7.9 30.8 0.17 10.3 13.9 2.3 2 0 0 2 2 2 0 Daxx Family Nop14 PF04147.7 EXF82941.1 - 1.3 6.8 35.2 1.9 6.3 3.5 2.2 2 0 0 2 2 2 0 Nop14-like family CAF-1_p150 PF11600.3 EXF82941.1 - 1.9 7.7 72.8 0.098 12.0 44.5 2.8 2 1 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Raftlin PF15250.1 EXF82941.1 - 4.5 5.6 17.0 16 3.9 11.4 1.9 2 0 0 2 2 2 0 Raftlin Ycf1 PF05758.7 EXF82941.1 - 7.3 4.1 24.8 14 3.2 17.2 1.3 1 0 0 1 1 1 0 Ycf1 DUF966 PF06136.8 EXF82941.1 - 8.4 5.7 21.7 7.5 5.8 13.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Glyco_hydro_28 PF00295.12 EXF82942.1 - 2.7e-33 115.3 0.7 2e-30 105.8 0.2 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EXF82942.1 - 0.077 12.7 11.1 0.38 10.4 3.0 2.8 1 1 1 2 2 2 0 Right handed beta helix region PAF-AH_p_II PF03403.8 EXF82944.1 - 1.4e-39 135.4 0.0 2.4e-35 121.5 0.0 2.2 2 0 0 2 2 2 2 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.2 EXF82944.1 - 3.4e-10 39.8 0.0 6.2e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF82944.1 - 0.0023 17.8 0.0 0.0048 16.8 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EXF82944.1 - 0.0046 15.8 0.0 0.0086 14.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Hydrolase_4 PF12146.3 EXF82944.1 - 0.0081 15.9 0.0 0.017 14.9 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase PF07224.6 EXF82944.1 - 0.024 13.4 0.0 0.041 12.6 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase DLH PF01738.13 EXF82944.1 - 0.039 13.2 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Pyr_redox_3 PF13738.1 EXF82945.1 - 2.4e-22 79.9 0.1 6.5e-21 75.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF82945.1 - 2.7e-15 56.1 0.0 5.3e-11 42.0 0.0 2.2 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EXF82945.1 - 8.3e-14 50.6 0.0 1.6e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EXF82945.1 - 4.4e-11 43.0 0.0 8.4e-07 29.0 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF82945.1 - 3.5e-07 30.1 0.0 9.6e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF82945.1 - 1.1e-05 24.5 3.0 0.033 13.1 0.0 3.2 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF82945.1 - 5.5e-05 22.1 4.0 0.093 11.5 0.3 3.2 3 0 0 3 3 3 2 FAD binding domain Pyr_redox PF00070.22 EXF82945.1 - 7.5e-05 23.0 0.1 0.14 12.5 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF82945.1 - 0.00016 20.8 0.1 0.055 12.5 0.0 3.0 3 0 0 3 3 3 1 Thi4 family FAD_oxidored PF12831.2 EXF82945.1 - 0.00024 20.3 0.1 0.00048 19.3 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EXF82945.1 - 0.00048 19.9 2.5 0.44 10.3 0.1 3.8 3 1 0 3 3 3 1 FAD-NAD(P)-binding SnoaL_2 PF12680.2 EXF82945.1 - 0.0012 19.2 0.1 0.0036 17.6 0.1 1.8 1 0 0 1 1 1 1 SnoaL-like domain Shikimate_DH PF01488.15 EXF82945.1 - 0.013 15.6 0.0 0.025 14.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 EXF82945.1 - 0.075 11.4 0.4 0.23 9.8 0.2 1.8 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_3 PF01494.14 EXF82945.1 - 0.11 11.5 1.9 8.1 5.3 0.2 2.7 2 1 1 3 3 3 0 FAD binding domain NAD_binding_7 PF13241.1 EXF82945.1 - 0.13 12.5 0.0 11 6.3 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding Peptidase_M18 PF02127.10 EXF82946.1 - 4.2e-120 401.1 0.0 4.9e-120 400.9 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) VEGF_C PF14554.1 EXF82946.1 - 0.2 11.4 0.2 4.4 7.1 0.4 2.2 2 0 0 2 2 2 0 VEGF heparin-binding domain EXS PF03124.9 EXF82947.1 - 1.2e-98 330.3 27.9 1.5e-98 330.0 19.3 1.1 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EXF82947.1 - 2.4e-57 194.8 1.6 4.9e-57 193.8 0.0 2.2 2 1 0 2 2 2 1 SPX domain DUF4414 PF14377.1 EXF82948.1 - 0.048 13.5 0.2 0.11 12.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4414) Methyltransf_23 PF13489.1 EXF82949.1 - 1e-23 83.8 0.0 1.5e-23 83.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF82949.1 - 4.7e-09 36.8 0.1 1.1e-07 32.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF82949.1 - 5.8e-09 35.7 0.0 7.1e-08 32.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF82949.1 - 1.4e-07 31.8 0.0 2.4e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF82949.1 - 1.1e-05 25.8 0.0 8.9e-05 22.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF82949.1 - 3.4e-05 24.1 0.0 0.0001 22.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF82949.1 - 0.002 17.1 1.5 0.0053 15.8 0.0 2.3 3 0 0 3 3 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 EXF82949.1 - 0.017 15.1 0.0 0.059 13.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EXF82949.1 - 0.064 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EXF82949.1 - 0.096 12.0 0.0 0.27 10.5 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase small domain FtsJ PF01728.14 EXF82949.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 EXF82950.1 - 2.4e-21 76.1 0.0 3.4e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF82950.1 - 3.5e-10 40.4 0.1 4.9e-09 36.7 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF82950.1 - 1e-09 38.1 0.0 7.6e-09 35.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF82950.1 - 4.4e-07 30.3 0.0 8.2e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF82950.1 - 4e-06 27.2 0.0 3e-05 24.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF82950.1 - 3.5e-05 24.1 0.0 8.4e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF82950.1 - 0.009 15.0 0.0 0.017 14.2 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_2 PF00891.13 EXF82950.1 - 0.017 14.3 0.0 0.037 13.2 0.0 1.7 2 0 0 2 2 2 0 O-methyltransferase PrmA PF06325.8 EXF82950.1 - 0.035 13.2 0.0 0.056 12.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.14 EXF82950.1 - 0.11 12.0 0.0 1.2 8.6 0.0 2.1 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EXF82950.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 EXF82950.1 - 0.14 12.2 0.0 0.42 10.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Fungal_trans_2 PF11951.3 EXF82951.1 - 2.3e-10 39.6 0.9 3.8e-10 38.9 0.6 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Peptidase_M43 PF05572.8 EXF82952.1 - 4.9e-18 65.1 0.1 1.1e-17 64.0 0.0 1.6 2 0 0 2 2 2 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 EXF82952.1 - 1.1e-05 25.9 0.8 4.3e-05 24.0 0.4 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EXF82952.1 - 2.4e-05 24.3 5.8 7.2e-05 22.7 4.0 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EXF82952.1 - 2.4e-05 24.4 5.3 4.3e-05 23.6 3.4 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EXF82952.1 - 0.0018 17.8 4.1 0.0054 16.2 2.8 1.8 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EXF82952.1 - 0.004 16.8 0.0 0.0049 16.6 0.0 1.3 1 1 0 1 1 1 1 Matrixin Peptidase_M54 PF07998.6 EXF82952.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M54 Peptidase_M57 PF12388.3 EXF82952.1 - 1 8.6 4.5 2.4 7.4 3.1 1.8 1 1 0 1 1 1 0 Dual-action HEIGH metallo-peptidase p450 PF00067.17 EXF82953.1 - 1.6e-11 43.4 0.0 4.6e-11 41.9 0.0 1.6 2 0 0 2 2 2 1 Cytochrome P450 p450 PF00067.17 EXF82954.1 - 6.6e-49 166.6 0.0 8.5e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 WSC PF01822.14 EXF82957.1 - 2.1e-65 216.6 69.2 3.5e-18 65.3 7.2 5.0 5 0 0 5 5 5 4 WSC domain PQQ_3 PF13570.1 EXF82957.1 - 0.0012 19.0 10.3 0.14 12.4 0.0 4.9 4 0 0 4 4 4 2 PQQ-like domain Gryzun-like PF12742.2 EXF82957.1 - 0.071 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking GATase PF00117.23 EXF82957.1 - 0.093 12.1 0.0 0.29 10.5 0.0 1.7 2 0 0 2 2 2 0 Glutamine amidotransferase class-I p450 PF00067.17 EXF82960.1 - 2.4e-54 184.5 0.0 6.6e-54 183.1 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Ribosomal_L7Ae PF01248.21 EXF82965.1 - 0.00043 19.7 0.0 0.001 18.5 0.0 1.6 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Glyco_hydro_16 PF00722.16 EXF82966.1 - 3.5e-15 55.7 1.3 5e-15 55.2 0.9 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 BRCT PF00533.21 EXF82967.1 - 0.001 19.1 0.0 0.0025 17.9 0.0 1.7 1 1 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain CAML PF14963.1 EXF82968.1 - 0.64 9.3 3.1 0.8 9.0 2.2 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand DUF2235 PF09994.4 EXF82970.1 - 5e-64 216.3 0.0 7e-64 215.8 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) Glyco_hydro_18 PF00704.23 EXF82972.1 - 3.7e-11 43.0 0.0 8.2e-11 41.9 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 18 DUF1980 PF09323.5 EXF82973.1 - 0.041 13.6 0.4 1.4 8.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) SPC12 PF06645.8 EXF82973.1 - 8.7 6.2 7.1 2.2 8.1 0.1 2.8 2 1 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) Fungal_trans PF04082.13 EXF82974.1 - 1.4e-41 142.1 1.0 2.5e-41 141.2 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EXF82974.1 - 1.2e-06 28.3 13.1 0.005 17.0 0.8 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF82974.1 - 1.4e-06 28.3 12.5 0.0012 19.0 1.3 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-met PF12874.2 EXF82974.1 - 0.0003 20.8 0.6 0.091 12.9 0.1 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EXF82974.1 - 0.01 15.9 2.3 0.16 12.1 0.0 2.9 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding FAD_binding_3 PF01494.14 EXF82975.1 - 1.3e-19 70.5 0.0 1.9e-12 46.9 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EXF82975.1 - 3e-08 32.9 3.9 0.013 14.3 4.3 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EXF82975.1 - 4.4e-06 25.6 0.9 0.014 14.0 0.3 2.1 1 1 1 2 2 2 2 Tryptophan halogenase HI0933_like PF03486.9 EXF82975.1 - 2.7e-05 22.8 0.8 0.012 14.1 1.5 2.1 2 0 0 2 2 2 2 HI0933-like protein NAD_binding_8 PF13450.1 EXF82975.1 - 0.00013 21.9 1.5 0.00013 21.9 1.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EXF82975.1 - 0.0024 16.7 5.8 0.0044 15.9 4.0 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EXF82975.1 - 0.017 15.5 2.1 0.13 12.7 1.4 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF82975.1 - 0.019 13.9 0.0 0.048 12.5 0.0 1.6 1 1 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EXF82975.1 - 0.031 14.3 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF82975.1 - 0.046 13.6 1.9 0.078 12.8 1.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_16 PF10294.4 EXF82975.1 - 0.1 12.0 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase 3HCDH_N PF02737.13 EXF82975.1 - 0.19 11.3 2.0 0.33 10.6 1.4 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Thi4 PF01946.12 EXF82975.1 - 0.2 10.7 0.5 0.4 9.7 0.3 1.4 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.2 EXF82975.1 - 0.41 9.6 4.4 0.63 9.0 3.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.17 EXF82975.1 - 1.9 7.2 5.7 2.7 6.7 3.9 1.1 1 0 0 1 1 1 0 Glucose inhibited division protein A PAN_4 PF14295.1 EXF82976.1 - 0.52 10.0 8.0 3.5 7.4 1.1 3.0 2 1 0 2 2 2 0 PAN domain Oxidored_FMN PF00724.15 EXF82977.1 - 9e-39 133.4 0.0 2e-38 132.2 0.0 1.5 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family CactinC_cactus PF09732.4 EXF82977.1 - 0.085 12.4 1.4 0.11 12.1 0.3 1.5 2 0 0 2 2 2 0 Cactus-binding C-terminus of cactin protein Oxidored_FMN PF00724.15 EXF82978.1 - 1.8e-41 142.2 0.0 2.2e-41 141.9 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family MFS_1 PF07690.11 EXF82979.1 - 4.8e-25 88.0 36.2 5.1e-19 68.1 8.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.14 EXF82980.1 - 2e-69 234.3 0.0 2.5e-69 234.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EXF82980.1 - 1e-19 70.7 0.0 5.5e-19 68.3 0.0 2.1 2 1 1 3 3 3 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 EXF82980.1 - 3.5e-05 24.1 0.0 0.0015 18.8 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF82980.1 - 5.7e-05 21.7 0.1 0.00046 18.7 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EXF82980.1 - 6.1e-05 22.9 0.0 0.00014 21.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EXF82980.1 - 0.00041 19.5 0.0 0.001 18.2 0.0 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EXF82980.1 - 0.0013 18.6 0.0 0.0038 17.1 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF82980.1 - 0.014 14.3 0.0 0.023 13.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF82980.1 - 0.018 13.9 0.1 0.027 13.4 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_binding_2 PF00890.19 EXF82980.1 - 0.032 13.0 0.1 0.061 12.1 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 EXF82980.1 - 0.046 13.0 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain XdhC_C PF13478.1 EXF82980.1 - 0.048 13.9 0.0 0.093 13.0 0.0 1.5 1 0 0 1 1 1 0 XdhC Rossmann domain Pyr_redox_3 PF13738.1 EXF82980.1 - 0.084 12.9 0.1 0.23 11.4 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EXF82980.1 - 0.087 11.9 0.0 0.17 11.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EXF82980.1 - 0.11 12.0 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amidase PF01425.16 EXF82981.1 - 9.1e-109 364.2 0.0 1.1e-108 363.9 0.0 1.1 1 0 0 1 1 1 1 Amidase Polysacc_deac_1 PF01522.16 EXF82982.1 - 9e-21 73.7 0.0 1.7e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2334 PF10096.4 EXF82982.1 - 0.027 13.8 0.1 0.074 12.4 0.0 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2334) p450 PF00067.17 EXF82983.1 - 2.7e-38 131.6 0.0 3.4e-38 131.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 ADH_zinc_N PF00107.21 EXF82984.1 - 1.9e-25 88.9 0.5 3.1e-25 88.1 0.4 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF82984.1 - 5.5e-17 62.8 0.1 1.4e-16 61.5 0.1 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF82984.1 - 8.3e-09 35.1 0.0 1.5e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EXF82984.1 - 0.00057 19.4 0.1 0.0011 18.5 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Acyl_transf_3 PF01757.17 EXF82985.1 - 1.9e-17 63.1 32.6 2.7e-17 62.6 22.6 1.3 1 0 0 1 1 1 1 Acyltransferase family 2OG-FeII_Oxy PF03171.15 EXF82986.1 - 4.1e-23 81.5 0.0 7.2e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EXF82986.1 - 0.00033 21.1 0.0 0.00094 19.7 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal Ring_hydroxyl_A PF00848.14 EXF82987.1 - 8e-34 117.1 2.0 3.5e-33 115.0 1.4 1.9 1 1 0 1 1 1 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.21 EXF82987.1 - 2.2e-14 52.7 0.0 4.3e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF4296 PF14129.1 EXF82987.1 - 0.16 12.1 0.0 0.35 11.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4296) NAD_binding_8 PF13450.1 EXF82989.1 - 0.00043 20.2 0.2 0.00082 19.3 0.1 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EXF82989.1 - 0.00083 19.1 0.2 0.0015 18.2 0.1 1.5 1 1 0 1 1 1 1 FAD-NAD(P)-binding DAO PF01266.19 EXF82989.1 - 0.0039 16.1 0.0 0.0046 15.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EXF82989.1 - 0.0049 15.9 0.0 0.0062 15.6 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EXF82989.1 - 0.0076 16.6 0.1 0.017 15.4 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF82989.1 - 0.083 11.9 0.1 0.15 11.1 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.1 EXF82989.1 - 0.085 12.9 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF82989.1 - 0.087 12.6 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF82989.1 - 0.17 10.6 0.6 0.24 10.1 0.4 1.2 1 0 0 1 1 1 0 FAD binding domain SET PF00856.23 EXF82990.1 - 1.3e-10 41.8 0.1 1.6e-09 38.2 0.0 2.3 1 1 1 2 2 2 1 SET domain FAD_binding_3 PF01494.14 EXF82991.1 - 1.7e-44 152.3 0.0 2.2e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EXF82991.1 - 0.057 12.5 0.0 0.093 11.8 0.0 1.2 1 0 0 1 1 1 0 Thi4 family COesterase PF00135.23 EXF82992.1 - 1.6e-54 185.5 0.0 1.1e-53 182.7 0.0 2.1 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF82992.1 - 4.3e-07 29.7 0.1 7.1e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF82992.1 - 0.004 16.9 0.1 0.012 15.3 0.1 1.9 2 1 0 2 2 2 1 Alpha/beta hydrolase family COesterase PF00135.23 EXF82993.1 - 2.6e-56 191.4 0.0 3.4e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF82993.1 - 2.6e-06 27.1 0.2 3.1e-05 23.6 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EXF82993.1 - 0.0019 18.1 0.3 0.0085 15.9 0.1 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF82993.1 - 0.017 14.8 0.0 0.035 13.8 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.8 EXF82993.1 - 0.16 11.5 0.5 0.27 10.7 0.0 1.6 2 0 0 2 2 2 0 PGAP1-like protein zf-H2C2_2 PF13465.1 EXF82994.1 - 2.7e-07 30.5 12.0 0.00011 22.2 3.7 2.8 2 0 0 2 2 2 2 Zinc-finger double domain Fungal_trans PF04082.13 EXF82994.1 - 6.6e-07 28.4 1.5 0.0091 14.8 0.2 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EXF82994.1 - 3.3e-06 27.1 16.1 0.0019 18.3 1.0 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF82994.1 - 4.2e-06 26.7 14.8 0.0044 17.2 0.7 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-BED PF02892.10 EXF82994.1 - 5.5 6.8 12.1 8.5 6.2 2.3 3.2 2 1 1 3 3 3 0 BED zinc finger p450 PF00067.17 EXF82995.1 - 1e-74 251.7 0.0 1.2e-74 251.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 HgmA PF04209.8 EXF82996.1 - 1e-152 508.4 0.0 1.2e-152 508.2 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FAD_binding_4 PF01565.18 EXF82997.1 - 3.2e-25 88.2 5.3 3.2e-25 88.2 3.7 1.6 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EXF82997.1 - 0.0016 18.3 0.0 0.0039 17.0 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like AAA_16 PF13191.1 EXF82998.1 - 3.3e-06 27.2 1.2 9.9e-06 25.6 0.0 2.4 3 0 0 3 3 3 1 AAA ATPase domain NACHT PF05729.7 EXF82998.1 - 3.4e-05 23.5 0.0 9.1e-05 22.1 0.0 1.7 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EXF82998.1 - 0.0006 19.9 0.0 0.026 14.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain Ank_4 PF13637.1 EXF82998.1 - 0.00093 19.6 0.1 0.021 15.3 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EXF82998.1 - 0.001 19.3 0.0 0.019 15.2 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) AAA_10 PF12846.2 EXF82998.1 - 0.079 12.3 0.6 0.52 9.6 0.1 2.3 2 1 1 3 3 3 0 AAA-like domain Sigma54_activat PF00158.21 EXF82998.1 - 0.15 11.5 0.0 0.29 10.5 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Enterotoxin_a PF01375.12 EXF82999.1 - 1.2e-49 169.0 1.3 1.4e-49 168.7 0.9 1.0 1 0 0 1 1 1 1 Heat-labile enterotoxin alpha chain DUF4419 PF14388.1 EXF83001.1 - 2.3e-16 59.8 0.0 2.9e-16 59.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) GcpE PF04551.9 EXF83001.1 - 0.0026 16.6 0.0 0.0033 16.2 0.0 1.1 1 0 0 1 1 1 1 GcpE protein ORC6 PF05460.8 EXF83002.1 - 0.077 12.0 3.4 0.088 11.8 2.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Med3 PF11593.3 EXF83002.1 - 0.53 9.4 6.6 0.65 9.1 4.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ADH_zinc_N PF00107.21 EXF83006.1 - 2.2e-21 75.7 0.5 2.2e-21 75.7 0.3 2.7 4 0 0 4 4 4 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF83006.1 - 1e-20 73.5 2.7 1.7e-20 72.7 1.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EXF83006.1 - 0.00028 21.7 1.1 0.00055 20.8 0.7 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EXF83006.1 - 0.002 18.7 0.6 0.0041 17.6 0.4 1.7 1 1 0 1 1 1 1 Methyltransferase domain Lipase_GDSL PF00657.17 EXF83007.1 - 2.3e-12 47.2 0.4 3.1e-12 46.8 0.3 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EXF83007.1 - 1.9e-10 41.1 2.9 3.6e-10 40.2 2.0 1.5 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family DUF1330 PF07045.6 EXF83007.1 - 0.034 13.9 0.3 5.5 6.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1330) Lactamase_B PF00753.22 EXF83008.1 - 4.3e-19 68.9 6.2 6.7e-19 68.2 4.3 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EXF83008.1 - 1.1e-05 25.0 0.1 1.8e-05 24.4 0.1 1.4 1 1 0 1 1 1 1 Beta-lactamase superfamily domain FAD_binding_4 PF01565.18 EXF83009.1 - 1.3e-19 70.0 3.6 1.4e-19 69.9 0.7 2.3 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.7 EXF83009.1 - 6.7e-07 29.1 0.0 1.3e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cu_amine_oxid PF01179.15 EXF83012.1 - 1.4e-167 557.6 0.0 1.8e-167 557.3 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EXF83012.1 - 2.5e-13 49.8 0.2 4.6e-13 49.0 0.2 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EXF83012.1 - 0.00016 21.6 0.0 0.0015 18.5 0.0 2.2 2 0 0 2 2 2 1 Copper amine oxidase, N3 domain Peptidase_M28 PF04389.12 EXF83013.1 - 3.7e-37 127.7 0.3 9.6e-37 126.4 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M20 PF01546.23 EXF83013.1 - 1.3e-08 34.5 0.3 2.5e-08 33.6 0.0 1.6 1 1 1 2 2 2 1 Peptidase family M20/M25/M40 Nicastrin PF05450.10 EXF83013.1 - 0.00024 20.4 0.2 0.0094 15.2 0.0 2.2 2 0 0 2 2 2 2 Nicastrin Kdo_hydroxy PF11004.3 EXF83014.1 - 0.02 13.8 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase DUF1212 PF06738.7 EXF83015.1 - 1.7e-53 180.9 5.6 3.3e-50 170.2 0.5 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EXF83015.1 - 2.3e-21 76.0 27.4 1e-12 48.0 0.6 3.9 4 0 0 4 4 4 3 Protein of unknown function (DUF3815) DUF2301 PF10063.4 EXF83015.1 - 0.012 15.7 3.4 0.038 14.1 2.4 1.8 1 0 0 1 1 1 0 Uncharacterized integral membrane protein (DUF2301) Hepcidin PF06446.7 EXF83016.1 - 0.1 13.0 2.6 0.26 11.7 1.1 2.0 2 0 0 2 2 2 0 Hepcidin Vps55 PF04133.9 EXF83016.1 - 0.41 10.3 3.3 0.65 9.7 2.3 1.3 1 0 0 1 1 1 0 Vacuolar protein sorting 55 DUF1840 PF08895.6 EXF83018.1 - 0.14 12.1 1.8 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) MFS_1 PF07690.11 EXF83019.1 - 1e-31 109.9 44.9 2.5e-30 105.4 16.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF83019.1 - 2.9e-30 105.2 24.0 2.3e-29 102.3 16.6 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter PIRT PF15099.1 EXF83019.1 - 0.017 14.3 0.3 0.017 14.3 0.2 1.7 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family Ank_2 PF12796.2 EXF83022.1 - 4.2e-51 171.2 0.0 2.7e-14 53.2 0.1 5.3 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EXF83022.1 - 2.6e-42 140.5 0.0 5.6e-06 25.8 0.0 8.8 8 0 0 8 8 8 7 Ankyrin repeat Ank_5 PF13857.1 EXF83022.1 - 2.5e-34 116.5 0.0 3.6e-06 27.0 0.1 7.2 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF83022.1 - 6e-25 84.8 0.0 0.0081 16.3 0.0 8.9 9 0 0 9 9 8 6 Ankyrin repeat Ank_4 PF13637.1 EXF83022.1 - 1.1e-23 83.0 0.0 7.8e-05 23.0 0.0 6.8 6 1 1 7 7 7 4 Ankyrin repeats (many copies) NACHT PF05729.7 EXF83022.1 - 5e-05 23.0 0.2 0.00056 19.6 0.0 2.9 3 1 0 3 3 3 1 NACHT domain AAA_22 PF13401.1 EXF83022.1 - 0.0004 20.5 0.0 0.0012 19.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EXF83022.1 - 0.035 14.0 0.0 0.14 12.1 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain DUF2075 PF09848.4 EXF83022.1 - 0.066 12.1 0.1 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.12 EXF83022.1 - 0.094 11.5 0.1 0.17 10.7 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_30 PF13604.1 EXF83022.1 - 0.31 10.5 0.0 0.56 9.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Peptidase_S8 PF00082.17 EXF83024.1 - 8.2e-20 71.1 0.0 1.8e-19 70.0 0.0 1.5 1 1 0 1 1 1 1 Subtilase family Y_phosphatase3 PF13350.1 EXF83026.1 - 1.8e-33 116.0 0.0 2.4e-33 115.7 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EXF83026.1 - 1.6e-08 34.5 0.0 6.9e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase PF00102.22 EXF83026.1 - 0.014 14.7 0.0 0.017 14.4 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EXF83026.1 - 0.018 14.4 0.0 0.028 13.7 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family DUF1470 PF07336.6 EXF83026.1 - 0.025 14.9 0.1 0.093 13.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1470) PTPlike_phytase PF14566.1 EXF83026.1 - 0.026 14.5 0.0 0.11 12.5 0.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate Amidohydro_3 PF07969.6 EXF83027.1 - 5.5e-63 213.5 0.1 6.4e-63 213.3 0.1 1.0 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.15 EXF83027.1 - 3.9e-06 26.7 0.5 0.0022 17.7 0.0 3.1 3 0 0 3 3 3 1 Amidohydrolase family Amidohydro_4 PF13147.1 EXF83027.1 - 0.0026 17.8 0.2 2.2 8.2 0.0 2.5 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EXF83027.1 - 0.0068 16.1 0.0 0.022 14.5 0.0 1.9 1 1 0 1 1 1 1 Amidohydrolase MFS_1 PF07690.11 EXF83028.1 - 4.8e-16 58.4 19.6 4.8e-16 58.4 13.6 2.6 1 1 1 3 3 3 2 Major Facilitator Superfamily Methyltransf_23 PF13489.1 EXF83029.1 - 2.3e-21 76.1 0.0 3.8e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF83029.1 - 5.2e-09 36.4 0.0 9.3e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF83029.1 - 7.6e-08 32.9 0.0 1.1e-06 29.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF83029.1 - 1.7e-07 30.9 0.0 1.8e-06 27.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF83029.1 - 4.8e-07 30.1 0.0 4.2e-06 27.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF83029.1 - 4.2e-05 23.8 0.0 0.00011 22.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF83029.1 - 0.023 14.0 0.0 0.055 12.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.13 EXF83029.1 - 0.035 13.2 0.0 0.31 10.1 0.0 2.2 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family DREV PF05219.7 EXF83029.1 - 0.11 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase PrmA PF06325.8 EXF83029.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Opy2 PF09463.5 EXF83030.1 - 2.5e-06 27.4 18.3 4.1e-06 26.7 12.7 1.3 1 0 0 1 1 1 1 Opy2 protein Mid2 PF04478.7 EXF83030.1 - 0.046 13.1 0.2 0.09 12.1 0.1 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor DUF2797 PF10977.3 EXF83030.1 - 0.68 9.5 3.2 1.1 8.7 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2797) Chitin_synth_1 PF01644.12 EXF83031.1 - 8.3e-70 233.8 0.0 1.2e-69 233.2 0.0 1.2 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.10 EXF83031.1 - 8.6e-28 97.0 0.1 1.9e-22 79.3 0.0 2.2 2 0 0 2 2 2 2 Chitin synthase Chitin_synth_1N PF08407.6 EXF83031.1 - 3.7e-27 93.8 0.2 1.2e-26 92.1 0.0 1.9 2 0 0 2 2 2 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.1 EXF83031.1 - 1.2e-10 41.4 0.1 1.2e-10 41.4 0.1 2.2 3 1 0 3 3 3 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.1 EXF83031.1 - 2.2e-08 34.1 0.0 4.4e-08 33.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase like family 2 UQ_con PF00179.21 EXF83032.1 - 3.7e-36 123.6 0.0 6e-36 122.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme eIF3_subunit PF08597.5 EXF83032.1 - 0.021 14.4 2.4 0.028 13.9 1.7 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Prok-E2_B PF14461.1 EXF83032.1 - 0.079 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic E2 family B IlvN PF07991.7 EXF83033.1 - 7.1e-46 155.5 0.0 1.2e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain IlvC PF01450.14 EXF83033.1 - 9e-45 152.1 0.0 1.3e-44 151.6 0.0 1.2 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EXF83033.1 - 0.025 15.0 0.1 0.11 12.8 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Kinetocho_Slk19 PF12709.2 EXF83034.1 - 4.6e-21 74.7 5.1 4.6e-21 74.7 3.5 4.0 2 2 0 4 4 4 2 Central kinetochore-associated Atg14 PF10186.4 EXF83034.1 - 1.5 7.7 23.3 0.1 11.4 6.1 2.2 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 IncA PF04156.9 EXF83034.1 - 4.2 6.9 23.1 1.5 8.4 6.5 2.4 2 0 0 2 2 2 0 IncA protein SNF2_N PF00176.18 EXF83035.1 - 2.8e-72 243.0 1.8 4.9e-72 242.2 1.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain DBINO PF13892.1 EXF83035.1 - 1.1e-50 171.3 20.3 1.1e-50 171.3 14.0 6.4 6 0 0 6 6 6 1 DNA-binding domain Helicase_C PF00271.26 EXF83035.1 - 5.4e-16 58.2 0.0 1.2e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Glyco_hydro_28 PF00295.12 EXF83037.1 - 1.2e-95 320.1 20.8 1.4e-95 319.9 14.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Beta_helix PF13229.1 EXF83037.1 - 0.024 14.3 27.1 0.27 10.9 18.8 2.6 1 1 0 1 1 1 0 Right handed beta helix region adh_short PF00106.20 EXF83038.1 - 4e-20 72.3 0.0 7.4e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF83038.1 - 1.4e-11 44.3 0.0 2.7e-11 43.4 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF83038.1 - 1.6e-05 24.4 0.0 2.8e-05 23.6 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EXF83038.1 - 0.0014 18.7 0.0 0.0027 17.8 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Glyco_tran_WecB PF03808.8 EXF83038.1 - 0.0032 16.9 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferase WecB/TagA/CpsF family Polysacc_synt_2 PF02719.10 EXF83038.1 - 0.0065 15.4 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Amidohydro_2 PF04909.9 EXF83038.1 - 0.016 14.7 0.1 0.12 11.9 0.0 2.1 2 1 0 2 2 2 0 Amidohydrolase Saccharop_dh PF03435.13 EXF83038.1 - 0.12 11.3 0.0 0.2 10.5 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase Glyco_hydro_43 PF04616.9 EXF83039.1 - 9.1e-68 228.4 0.1 1.2e-67 228.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Acetyltransf_3 PF13302.1 EXF83040.1 - 2.5e-13 50.4 0.0 3.8e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EXF83040.1 - 0.0065 16.4 0.0 0.0093 15.9 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain BmKX PF09132.5 EXF83041.1 - 0.043 13.6 0.9 0.11 12.4 0.6 1.6 1 0 0 1 1 1 0 BmKX DUF4593 PF15263.1 EXF83041.1 - 0.078 12.8 0.5 0.13 12.1 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4593) DUF3157 PF11355.3 EXF83041.1 - 0.095 11.9 0.2 0.13 11.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3157) B3 PF02362.16 EXF83043.1 - 0.12 12.0 0.0 0.17 11.5 0.0 1.4 1 1 0 1 1 1 0 B3 DNA binding domain Glyco_hydro_20 PF00728.17 EXF83044.1 - 1.3e-38 133.1 0.0 1.7e-38 132.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.10 EXF83044.1 - 5e-07 30.2 0.1 1.6e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 HATPase_c PF02518.21 EXF83045.1 - 1.6e-21 76.1 0.2 2.8e-21 75.3 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EXF83045.1 - 1.7e-19 69.8 0.0 7e-19 67.8 0.0 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EXF83045.1 - 5.6e-12 45.4 0.2 9.6e-11 41.5 0.1 2.5 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain AA_permease_2 PF13520.1 EXF83046.1 - 1.3e-58 198.5 55.1 1.6e-58 198.2 38.2 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF83046.1 - 2.3e-27 95.5 52.0 2.9e-27 95.1 36.0 1.0 1 0 0 1 1 1 1 Amino acid permease NUDIX PF00293.23 EXF83047.1 - 7e-15 54.8 0.3 2.2e-13 50.0 0.1 2.4 2 1 0 2 2 2 2 NUDIX domain F-box-like PF12937.2 EXF83048.1 - 0.00063 19.4 0.3 0.0018 17.9 0.2 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EXF83048.1 - 0.0046 16.5 0.9 0.019 14.6 0.6 2.1 1 1 0 1 1 1 1 F-box domain Glyco_hydro_26 PF02156.10 EXF83049.1 - 2.6e-93 312.9 7.2 3.3e-93 312.6 5.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 26 p450 PF00067.17 EXF83050.1 - 5.2e-28 97.7 0.0 1.1e-27 96.6 0.0 1.5 1 1 0 1 1 1 1 Cytochrome P450 Glyco_hydro_6 PF01341.12 EXF83051.1 - 4.5e-87 292.2 0.4 5.1e-87 292.0 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 6 p450 PF00067.17 EXF83052.1 - 5.5e-28 97.6 0.5 1.8e-25 89.4 0.1 2.2 2 0 0 2 2 2 2 Cytochrome P450 OTT_1508_deam PF14441.1 EXF83053.1 - 1.7e-21 76.5 0.0 2.4e-21 76.0 0.0 1.2 1 0 0 1 1 1 1 OTT_1508-like deaminase Haem_bd PF14376.1 EXF83055.1 - 0.11 12.2 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Haem-binding domain Vanabin-2 PF11437.3 EXF83055.1 - 0.24 11.4 6.2 0.28 11.1 4.3 1.2 1 0 0 1 1 1 0 Vanadium-binding protein 2 Fer4_6 PF12837.2 EXF83055.1 - 5 7.1 12.6 0.82 9.6 3.3 2.8 1 1 1 2 2 2 0 4Fe-4S binding domain DUF1656 PF07869.7 EXF83057.1 - 0.057 13.2 0.4 0.057 13.2 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1656) DoxX PF07681.7 EXF83057.1 - 0.065 13.6 0.2 0.29 11.5 0.0 1.9 1 1 1 2 2 2 0 DoxX FAD_binding_3 PF01494.14 EXF83058.1 - 4.9e-90 302.1 0.0 6.4e-90 301.7 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Phe_hydrox_dim PF07976.7 EXF83058.1 - 4e-57 192.5 0.0 6.7e-57 191.7 0.0 1.4 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain FAD_binding_2 PF00890.19 EXF83058.1 - 3.5e-05 22.8 0.2 6.4e-05 21.9 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EXF83058.1 - 4.4e-05 22.1 0.4 7e-05 21.4 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EXF83058.1 - 0.00068 19.5 0.4 0.0018 18.1 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF83058.1 - 0.0014 17.7 0.0 0.01 14.9 0.0 2.1 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 EXF83058.1 - 0.014 14.3 0.4 0.022 13.6 0.3 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_8 PF13450.1 EXF83058.1 - 0.018 15.0 0.3 0.085 12.8 0.1 2.3 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EXF83058.1 - 0.032 13.1 0.1 0.067 12.1 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.2 EXF83058.1 - 0.033 13.2 0.3 0.054 12.5 0.2 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EXF83058.1 - 0.062 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.9 EXF83058.1 - 0.084 11.4 0.0 0.18 10.3 0.0 1.6 1 0 0 1 1 1 0 Tryptophan halogenase DAO PF01266.19 EXF83058.1 - 0.086 11.7 0.1 0.19 10.5 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EXF83058.1 - 0.13 12.6 0.0 0.34 11.3 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase OTT_1508_deam PF14441.1 EXF83060.1 - 9.8e-19 67.5 0.0 2e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 OTT_1508-like deaminase MOR2-PAG1_N PF14222.1 EXF83060.1 - 0.1 11.2 0.0 0.22 10.1 0.0 1.4 2 0 0 2 2 2 0 Cell morphogenesis N-terminal Cupin_2 PF07883.6 EXF83062.1 - 7.7e-13 47.7 0.2 1.6e-09 37.1 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EXF83062.1 - 0.002 17.5 0.1 0.26 10.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF861) AraC_binding PF02311.14 EXF83062.1 - 0.0061 16.2 0.0 0.06 13.0 0.0 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain DUF1255 PF06865.6 EXF83062.1 - 0.0079 16.4 0.0 0.051 13.8 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1255) Cupin_4 PF08007.7 EXF83062.1 - 0.074 12.2 0.3 0.22 10.7 0.0 1.8 2 0 0 2 2 2 0 Cupin superfamily protein Abhydrolase_3 PF07859.8 EXF83063.1 - 3.8e-15 56.0 0.0 3.5e-09 36.5 0.0 2.5 3 0 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EXF83063.1 - 3.3e-12 46.0 0.1 3.4e-08 32.9 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EXF83063.1 - 6.5e-10 38.9 0.0 1.1e-09 38.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF83063.1 - 4.7e-09 36.4 0.0 7.7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EXF83063.1 - 4.8e-07 28.8 0.0 9.8e-07 27.8 0.0 1.4 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_2 PF02230.11 EXF83063.1 - 2.7e-06 27.0 0.0 0.0027 17.2 0.0 2.3 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Peptidase_S15 PF02129.13 EXF83063.1 - 0.0004 19.8 0.0 0.0022 17.4 0.0 2.0 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DLH PF01738.13 EXF83063.1 - 0.0014 17.9 0.0 0.0031 16.8 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family LIP PF03583.9 EXF83063.1 - 0.033 13.4 0.0 0.073 12.2 0.0 1.5 2 0 0 2 2 2 0 Secretory lipase AXE1 PF05448.7 EXF83063.1 - 0.066 11.7 0.0 0.62 8.5 0.0 2.0 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) FSH1 PF03959.8 EXF83063.1 - 0.13 11.6 0.0 0.4 10.0 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Sugar_tr PF00083.19 EXF83064.1 - 5.4e-60 203.2 29.5 6.1e-60 203.0 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF83064.1 - 2.3e-18 66.0 34.7 2.3e-18 66.0 24.0 2.6 1 1 2 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.1 EXF83064.1 - 0.00047 18.6 9.1 0.00047 18.6 6.3 3.6 3 1 1 4 4 4 3 MFS/sugar transport protein DUF3671 PF12420.3 EXF83064.1 - 0.48 10.4 7.9 0.78 9.7 0.5 3.4 3 1 0 3 3 3 0 Protein of unknown function Fungal_trans PF04082.13 EXF83065.1 - 1e-18 67.2 0.0 2.3e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF83065.1 - 1.4e-06 28.0 10.4 1.4e-06 28.0 7.2 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_3 PF00933.16 EXF83066.1 - 1.4e-73 247.4 0.0 3.9e-73 246.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF83066.1 - 1e-59 201.8 0.0 7.6e-59 198.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF83066.1 - 2e-21 75.6 0.5 4.2e-21 74.6 0.3 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EXF83066.1 - 6.6e-07 29.0 0.0 1.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Transposase_23 PF03017.9 EXF83066.1 - 0.1 12.1 0.1 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 TNP1/EN/SPM transposase Peptidase_S8 PF00082.17 EXF83068.1 - 2e-46 158.3 6.3 1.8e-45 155.2 4.1 2.2 2 0 0 2 2 2 1 Subtilase family DUF1034 PF06280.7 EXF83068.1 - 2.8e-10 40.5 0.1 6.9e-10 39.3 0.1 1.7 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 EXF83068.1 - 5e-05 22.9 0.0 0.00014 21.4 0.0 1.8 1 0 0 1 1 1 1 PA domain DUF916 PF06030.7 EXF83068.1 - 0.097 12.4 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) FixG_C PF11614.3 EXF83068.1 - 0.17 11.9 0.0 0.76 9.8 0.0 1.9 1 1 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Lactamase_B PF00753.22 EXF83070.1 - 3.7e-13 49.5 1.0 4.3e-13 49.3 0.7 1.4 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EXF83070.1 - 7.4e-07 28.8 0.1 1.1e-06 28.3 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EXF83070.1 - 0.012 15.3 0.0 0.024 14.3 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain FAD_binding_4 PF01565.18 EXF83071.1 - 8.4e-18 64.1 0.7 1.4e-17 63.4 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EXF83072.1 - 9.7e-44 149.8 0.0 1.4e-43 149.3 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EXF83072.1 - 0.00071 19.6 0.0 0.067 13.2 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_8 PF13450.1 EXF83072.1 - 0.0013 18.6 0.4 0.0093 15.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EXF83072.1 - 0.025 14.3 0.0 0.86 9.3 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding DAO PF01266.19 EXF83072.1 - 0.025 13.4 0.1 0.62 8.9 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 EXF83072.1 - 0.13 11.3 0.1 0.58 9.1 0.0 2.0 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 EXF83072.1 - 0.17 10.8 0.0 2.8 6.8 0.0 2.1 2 0 0 2 2 2 0 FAD binding domain ThiF PF00899.16 EXF83072.1 - 0.21 11.3 0.4 2.7 7.8 0.1 2.3 2 0 0 2 2 2 0 ThiF family Fungal_trans PF04082.13 EXF83073.1 - 4.7e-10 38.7 0.0 9e-10 37.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4243 PF14027.1 EXF83074.1 - 4.6e-76 256.3 3.0 6.3e-76 255.9 2.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4243) Pyr_redox_3 PF13738.1 EXF83076.1 - 7.2e-18 65.3 0.0 6.9e-17 62.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF83076.1 - 3.8e-12 45.8 0.1 7.2e-09 35.0 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EXF83076.1 - 2.8e-06 27.3 0.0 1.2e-05 25.2 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EXF83076.1 - 5.9e-05 21.4 0.5 0.001 17.3 0.1 2.5 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox PF00070.22 EXF83076.1 - 0.00017 21.8 0.0 0.0061 16.9 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase CPSase_L_chain PF00289.17 EXF83076.1 - 0.0016 18.5 0.0 0.51 10.4 0.0 2.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Lycopene_cycl PF05834.7 EXF83076.1 - 0.0022 16.9 0.3 0.031 13.1 0.1 2.4 2 1 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.14 EXF83076.1 - 0.0035 16.4 0.0 0.011 14.8 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EXF83076.1 - 0.0044 17.0 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF83076.1 - 0.0046 15.8 0.3 0.32 9.8 0.0 2.8 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EXF83076.1 - 0.015 14.3 0.0 0.025 13.6 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EXF83076.1 - 0.018 14.7 1.3 8.3 6.1 0.3 2.9 2 1 0 2 2 2 0 FAD-NAD(P)-binding 2-Hacid_dh_C PF02826.14 EXF83076.1 - 0.023 13.8 0.0 0.048 12.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thi4 PF01946.12 EXF83076.1 - 0.056 12.5 0.0 0.16 11.0 0.0 1.7 2 0 0 2 2 2 0 Thi4 family rve_2 PF13333.1 EXF83076.1 - 0.085 12.9 0.2 0.16 12.0 0.2 1.4 1 0 0 1 1 1 0 Integrase core domain DUF632 PF04782.7 EXF83077.1 - 0.047 12.7 1.0 0.071 12.1 0.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF632) DUF1183 PF06682.7 EXF83078.1 - 0.001 18.7 0.5 0.0021 17.7 0.4 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) DAG1 PF05454.6 EXF83078.1 - 0.0017 17.6 0.0 0.0024 17.1 0.0 1.3 1 0 0 1 1 1 1 Dystroglycan (Dystrophin-associated glycoprotein 1) Shisa PF13908.1 EXF83078.1 - 0.027 14.6 0.0 0.028 14.5 0.0 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 EXF83078.1 - 0.04 14.3 0.2 0.07 13.5 0.1 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF4330 PF14221.1 EXF83078.1 - 0.042 13.6 0.1 0.058 13.2 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4330) Herpes_gE PF02480.11 EXF83078.1 - 0.044 12.0 0.0 0.044 12.0 0.0 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Phage_Coat_B PF05356.6 EXF83078.1 - 0.045 13.4 0.3 0.09 12.4 0.2 1.5 1 0 0 1 1 1 0 Phage Coat protein B PsaL PF02605.10 EXF83078.1 - 0.052 13.0 0.0 0.062 12.8 0.0 1.2 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI IncA PF04156.9 EXF83078.1 - 0.079 12.5 0.1 0.1 12.1 0.1 1.1 1 0 0 1 1 1 0 IncA protein TMEM52 PF14979.1 EXF83078.1 - 0.11 12.4 0.1 0.62 9.9 0.0 1.8 2 0 0 2 2 2 0 Transmembrane 52 Rax2 PF12768.2 EXF83078.1 - 0.13 11.4 0.1 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Cortical protein marker for cell polarity RCR PF12273.3 EXF83078.1 - 0.41 11.2 3.6 1.3 9.5 2.5 1.8 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red FAD_binding_4 PF01565.18 EXF83079.1 - 9.1e-21 73.7 0.5 1.4e-20 73.2 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF83079.1 - 0.054 13.4 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 Berberine and berberine like Sugar_tr PF00083.19 EXF83080.1 - 5.6e-85 285.5 28.2 6.9e-85 285.2 19.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF83080.1 - 2.1e-28 99.0 28.3 2.1e-28 99.0 19.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Imm40 PF15582.1 EXF83080.1 - 0.04 12.6 0.2 0.061 12.0 0.2 1.2 1 0 0 1 1 1 0 Immunity protein 40 DUF1049 PF06305.6 EXF83080.1 - 0.04 13.3 1.4 0.14 11.6 0.3 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1049) MR_MLE_C PF13378.1 EXF83081.1 - 6e-20 71.2 0.4 1.5e-19 69.9 0.1 1.9 1 1 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EXF83081.1 - 2.7e-13 50.2 1.0 5.8e-13 49.1 0.2 1.9 2 0 0 2 2 2 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EXF83081.1 - 0.026 14.5 0.1 0.058 13.4 0.0 1.8 1 1 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain Fungal_trans PF04082.13 EXF83082.1 - 9.5e-18 64.0 0.5 2.1e-17 62.8 0.3 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sugar_tr PF00083.19 EXF83083.1 - 5.7e-96 321.8 18.6 6.6e-96 321.6 12.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF83083.1 - 8.3e-39 133.2 33.6 3.5e-32 111.4 10.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF83083.1 - 1.8e-07 29.7 10.4 2.6e-05 22.6 1.5 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) 2-Hacid_dh_C PF02826.14 EXF83084.1 - 1.3e-48 164.5 0.1 1.9e-48 163.9 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EXF83084.1 - 6.1e-08 32.2 0.0 7.5e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EXF83084.1 - 0.00021 21.1 0.1 0.0003 20.6 0.1 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase MFS_1 PF07690.11 EXF83085.1 - 7.2e-25 87.4 20.7 7.8e-25 87.3 13.9 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF2776 PF10951.3 EXF83085.1 - 0.0022 17.1 1.2 0.23 10.5 0.0 2.8 3 1 1 4 4 4 2 Protein of unknown function (DUF2776) M20_dimer PF07687.9 EXF83086.1 - 3.1e-06 26.9 0.1 1e-05 25.1 0.1 1.9 1 0 0 1 1 1 1 Peptidase dimerisation domain BCS1_N PF08740.6 EXF83089.1 - 1.3e-42 145.5 0.3 1.3e-42 145.5 0.2 1.7 2 0 0 2 2 2 1 BCS1 N terminal AAA PF00004.24 EXF83089.1 - 2.1e-16 60.3 0.0 1.5e-07 31.6 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EXF83089.1 - 0.00035 21.3 0.0 0.00095 19.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EXF83089.1 - 0.00095 18.6 0.0 0.0018 17.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EXF83089.1 - 0.0048 15.9 0.0 0.0082 15.2 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EXF83089.1 - 0.027 14.1 0.0 0.094 12.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EXF83089.1 - 0.041 13.4 0.4 0.11 12.1 0.3 1.6 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EXF83089.1 - 0.058 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 KaiC Tau95 PF09734.4 EXF83090.1 - 5e-64 216.5 0.0 6.5e-64 216.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit Daxx PF03344.10 EXF83090.1 - 1.5 7.1 10.4 2.3 6.6 7.2 1.1 1 0 0 1 1 1 0 Daxx Family B56 PF01603.15 EXF83091.1 - 4.5e-174 578.8 5.5 5.5e-174 578.5 3.8 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Pinin_SDK_N PF04697.8 EXF83091.1 - 1.2 9.1 10.1 0.16 11.9 3.6 1.9 2 0 0 2 2 2 0 pinin/SDK conserved region CTD_bind PF04818.8 EXF83092.1 - 2.5e-06 27.6 0.0 7e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase II-binding domain. KAR9 PF08580.5 EXF83092.1 - 2.5 6.2 6.0 3.1 5.9 4.1 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Exo_endo_phos PF03372.18 EXF83095.1 - 7.1e-26 91.6 0.0 1.3e-25 90.7 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family BBS2_Mid PF14783.1 EXF83095.1 - 0.038 13.7 0.1 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region DUF2442 PF10387.4 EXF83095.1 - 0.19 11.7 0.0 1.3 9.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2442) Orn_Arg_deC_N PF02784.11 EXF83096.1 - 3.5e-79 265.5 0.0 4.8e-79 265.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EXF83096.1 - 3.5e-32 110.5 0.0 6.5e-32 109.6 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain M16C_assoc PF08367.6 EXF83097.1 - 2.1e-61 206.9 0.0 3e-61 206.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EXF83097.1 - 1e-36 126.3 0.0 3.7e-21 75.6 0.0 3.2 5 0 0 5 5 5 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EXF83097.1 - 5.7e-08 32.6 0.1 1.1e-06 28.4 0.0 2.9 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Taxilin PF09728.4 EXF83098.1 - 5.3e-83 278.6 58.5 5.3e-83 278.6 40.6 1.6 1 1 1 2 2 2 2 Myosin-like coiled-coil protein Syntaxin PF00804.20 EXF83098.1 - 0.0021 18.1 1.6 0.0021 18.1 1.1 4.4 2 1 1 3 3 3 1 Syntaxin HNF-1B_C PF04812.8 EXF83099.1 - 0.057 12.6 1.0 0.094 11.9 0.1 1.7 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus NUP50 PF08911.6 EXF83099.1 - 0.15 12.4 4.1 0.46 10.8 0.2 3.2 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) zf-C2H2 PF00096.21 EXF83101.1 - 6.1e-17 60.8 20.7 0.001 19.2 0.1 5.6 5 0 0 5 5 5 5 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF83101.1 - 2.6e-13 49.2 16.8 0.0057 16.9 0.0 5.5 5 0 0 5 5 5 5 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EXF83101.1 - 5.3e-13 48.3 14.2 1e-05 25.2 0.1 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.2 EXF83101.1 - 3.6e-08 33.3 12.9 0.082 13.1 0.2 5.7 5 1 1 6 6 6 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EXF83101.1 - 8.5e-07 28.9 6.7 0.7 10.1 0.0 5.4 5 0 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EXF83101.1 - 2.1e-05 24.5 12.8 1.5 8.9 0.3 5.2 2 2 3 5 5 5 2 C2H2 type zinc-finger (2 copies) zf-H2C2_2 PF13465.1 EXF83101.1 - 4.2e-05 23.6 20.0 0.001 19.2 0.1 5.2 5 0 0 5 5 5 1 Zinc-finger double domain zf-Di19 PF05605.7 EXF83101.1 - 0.0004 20.4 14.8 0.013 15.5 2.1 3.8 3 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-RING_5 PF14634.1 EXF83101.1 - 0.02 14.6 4.7 0.02 14.6 3.2 2.9 2 1 1 3 3 3 0 zinc-RING finger domain zf-C2HC_2 PF13913.1 EXF83101.1 - 0.021 14.4 13.5 13 5.5 0.3 5.2 5 0 0 5 5 5 0 zinc-finger of a C2HC-type Trm112p PF03966.11 EXF83101.1 - 0.066 13.5 2.4 0.51 10.7 0.3 2.8 2 1 0 2 2 2 0 Trm112p-like protein RRN7 PF11781.3 EXF83101.1 - 0.095 12.2 2.2 20 4.8 0.0 3.7 3 0 0 3 3 3 0 RNA polymerase I-specific transcription initiation factor Rrn7 zf-RING_3 PF14369.1 EXF83101.1 - 0.2 11.6 2.5 1.2 9.2 0.0 3.3 3 0 0 3 3 3 0 zinc-finger zinc-ribbons_6 PF07191.7 EXF83101.1 - 0.56 10.0 11.6 4.6 7.1 0.3 4.0 3 1 1 4 4 4 0 zinc-ribbons DUF629 PF04780.7 EXF83101.1 - 0.56 8.6 7.4 5 5.5 0.1 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF629) DZR PF12773.2 EXF83101.1 - 1.6 8.6 11.7 1.7 8.5 2.8 3.4 2 2 0 2 2 2 0 Double zinc ribbon zf-C3HC4_3 PF13920.1 EXF83101.1 - 3.9 7.2 12.0 0.21 11.2 2.5 2.9 2 2 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 EXF83101.1 - 6.1 6.3 10.6 10 5.6 0.3 4.4 3 1 2 5 5 5 0 Rad50 zinc hook motif ATPase-cat_bd PF12156.3 EXF83101.1 - 7 7.2 8.1 1.5 9.3 0.8 3.1 3 1 0 3 3 2 0 Putative metal-binding domain of cation transport ATPase DUF3795 PF12675.2 EXF83101.1 - 7.9 6.7 11.8 0.76 10.0 0.8 3.0 3 1 0 3 3 2 0 Protein of unknown function (DUF3795) Pol_alpha_B_N PF08418.5 EXF83102.1 - 3.4e-61 207.0 0.2 5.5e-61 206.2 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal DNA_pol_E_B PF04042.11 EXF83102.1 - 2.7e-42 144.3 0.1 3.9e-42 143.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Prp19_bind PF06991.6 EXF83103.1 - 7.2e-42 143.5 28.5 7.2e-42 143.5 19.8 2.6 2 1 1 3 3 3 1 Splicing factor, Prp19-binding domain Alb1 PF09135.6 EXF83104.1 - 1.4e-22 80.4 17.7 2.4e-22 79.6 12.3 1.4 1 0 0 1 1 1 1 Alb1 Transposase_22 PF02994.9 EXF83104.1 - 0.0072 14.8 6.1 0.0084 14.6 4.2 1.1 1 0 0 1 1 1 1 L1 transposable element eIF-3_zeta PF05091.7 EXF83104.1 - 0.47 9.0 9.2 0.58 8.7 6.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3020 PF11223.3 EXF83104.1 - 2.1 8.8 0.1 2.1 8.8 0.0 4.6 4 1 0 4 4 4 0 Protein of unknown function (DUF3020) UCH PF00443.24 EXF83105.1 - 3.5e-38 131.2 0.0 4.8e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EXF83105.1 - 3.6e-05 23.3 0.0 9.2e-05 22.0 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Octopine_DH PF02317.12 EXF83105.1 - 0.098 12.3 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain HAMP PF00672.20 EXF83105.1 - 7 6.9 6.4 2.2 8.5 0.1 2.7 2 0 0 2 2 2 0 HAMP domain TENA_THI-4 PF03070.11 EXF83106.1 - 7.1e-05 22.6 0.0 0.13 11.9 0.0 2.3 2 0 0 2 2 2 2 TENA/THI-4/PQQC family TPT PF03151.11 EXF83107.1 - 7.3e-28 97.1 14.6 7.3e-28 97.1 10.1 2.6 2 1 1 3 3 3 1 Triose-phosphate Transporter family UAA PF08449.6 EXF83107.1 - 9.9e-05 21.3 22.9 0.0011 17.9 15.9 2.1 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EXF83107.1 - 0.032 14.2 38.1 0.13 12.3 9.5 2.8 3 0 0 3 3 3 0 EamA-like transporter family Glyco_transf_17 PF04724.8 EXF83109.1 - 6.2e-48 163.6 0.8 8.2e-48 163.2 0.6 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 17 COMPASS-Shg1 PF05205.7 EXF83110.1 - 3e-25 88.5 0.2 3e-25 88.5 0.1 2.7 3 0 0 3 3 3 1 COMPASS (Complex proteins associated with Set1p) component shg1 PGA2 PF07543.7 EXF83111.1 - 5.5e-40 136.4 0.3 6.3e-40 136.2 0.2 1.0 1 0 0 1 1 1 1 Protein trafficking PGA2 DUF3989 PF13150.1 EXF83111.1 - 0.047 13.1 0.6 0.096 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) CENP-S PF15630.1 EXF83112.1 - 1.1e-34 118.3 0.1 1.6e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 EXF83112.1 - 0.00029 20.5 0.1 0.0024 17.5 0.0 2.0 1 1 1 2 2 2 1 Bromodomain associated TFIID-18kDa PF02269.11 EXF83112.1 - 0.0031 17.3 0.0 0.0043 16.8 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CENP-T PF15511.1 EXF83112.1 - 0.0057 15.9 0.1 0.0077 15.5 0.1 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Histone PF00125.19 EXF83112.1 - 0.0085 16.1 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.10 EXF83112.1 - 0.03 14.0 0.0 0.034 13.9 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Transgly PF00912.17 EXF83112.1 - 0.042 13.1 0.0 0.055 12.7 0.0 1.1 1 0 0 1 1 1 0 Transglycosylase DUF2773 PF10971.3 EXF83112.1 - 0.056 13.4 0.0 0.073 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2773) Catalase-rel PF06628.7 EXF83112.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Catalase-related immune-responsive WD40 PF00400.27 EXF83114.1 - 7.2e-71 231.7 18.2 7.5e-09 35.1 0.0 11.8 11 0 0 11 11 11 11 WD domain, G-beta repeat Utp13 PF08625.6 EXF83114.1 - 2.8e-44 150.1 0.1 4.2e-44 149.6 0.1 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EXF83114.1 - 2.4e-07 29.2 4.0 0.0013 17.0 0.0 4.9 3 2 2 5 5 5 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EXF83114.1 - 1.1e-05 24.3 0.7 0.68 8.6 0.0 5.2 5 1 0 6 6 6 2 Nup133 N terminal like TPR_12 PF13424.1 EXF83115.1 - 3.1e-30 103.9 14.9 2.8e-10 40.0 0.1 5.5 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 EXF83115.1 - 7e-28 95.7 26.1 1.6e-05 24.6 0.0 7.1 7 0 0 7 7 6 6 Tetratricopeptide repeat PNP_UDP_1 PF01048.15 EXF83115.1 - 7.6e-16 57.7 0.2 2.8e-15 55.9 0.2 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily TPR_2 PF07719.12 EXF83115.1 - 7.5e-10 37.9 9.8 0.011 15.6 0.1 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 EXF83115.1 - 2.4e-09 36.7 6.7 6.4e-05 22.5 0.1 4.4 3 1 1 4 4 4 3 TPR repeat TPR_7 PF13176.1 EXF83115.1 - 8e-09 34.6 15.5 0.02 14.6 0.3 6.0 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 EXF83115.1 - 7e-07 28.5 6.9 0.69 9.6 0.1 5.3 6 0 0 6 6 6 3 Tetratricopeptide repeat AAA_22 PF13401.1 EXF83115.1 - 2.7e-06 27.5 0.0 1.2e-05 25.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EXF83115.1 - 5.8e-06 25.3 0.0 1.7e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 NB-ARC domain TPR_8 PF13181.1 EXF83115.1 - 9.6e-06 25.0 4.5 0.66 9.9 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EXF83115.1 - 2.1e-05 25.0 0.4 0.00058 20.4 0.0 4.8 5 1 0 5 5 3 2 Tetratricopeptide repeat Apc3 PF12895.2 EXF83115.1 - 0.00028 20.9 2.8 0.00059 19.9 0.1 2.9 2 1 1 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_4 PF07721.9 EXF83115.1 - 0.00038 20.5 6.6 3.5 8.3 0.0 5.5 5 0 0 5 5 4 1 Tetratricopeptide repeat PPR PF01535.15 EXF83115.1 - 0.00041 20.1 0.0 2.4 8.3 0.0 3.8 3 0 0 3 3 3 1 PPR repeat TPR_14 PF13428.1 EXF83115.1 - 0.0031 18.0 17.2 1.1 10.0 0.1 6.5 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EXF83115.1 - 0.0036 17.6 19.0 0.021 15.1 0.1 5.9 5 1 3 8 8 5 2 Tetratricopeptide repeat TPR_20 PF14561.1 EXF83115.1 - 0.0051 16.9 10.4 0.37 10.9 0.0 4.8 4 1 2 6 6 5 2 Tetratricopeptide repeat TPR_21 PF09976.4 EXF83115.1 - 0.0054 16.6 0.3 0.02 14.8 0.2 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 EXF83115.1 - 0.0067 16.5 0.0 10 6.6 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EXF83115.1 - 2.1 8.9 10.4 17 6.1 0.0 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat UCH PF00443.24 EXF83116.1 - 7.7e-26 90.7 0.0 1.2e-25 90.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EXF83116.1 - 5.8e-12 45.5 0.3 5.8e-12 45.5 0.2 1.9 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EXF83116.1 - 0.012 15.1 0.0 0.02 14.3 0.0 1.4 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase IF4E PF01652.13 EXF83117.1 - 7.6e-49 165.4 0.1 9.9e-49 165.0 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Apc3 PF12895.2 EXF83118.1 - 4.3e-27 94.0 20.2 1.4e-21 76.3 0.7 6.1 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EXF83118.1 - 1e-23 81.8 11.5 3.7e-05 23.1 0.6 9.8 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.1 EXF83118.1 - 2.6e-22 78.2 23.4 1.5e-07 30.9 0.0 8.2 5 2 4 9 9 9 7 TPR repeat TPR_2 PF07719.12 EXF83118.1 - 5.4e-21 72.7 24.3 0.00024 20.7 0.3 10.5 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_19 PF14559.1 EXF83118.1 - 1.6e-20 73.1 19.1 0.0018 18.5 0.0 8.4 5 3 1 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.1 EXF83118.1 - 1.1e-18 66.8 19.2 0.0016 18.3 0.0 8.6 5 2 2 7 7 7 5 Tetratricopeptide repeat TPR_14 PF13428.1 EXF83118.1 - 8.3e-14 50.8 18.8 0.24 12.1 0.0 10.2 5 2 6 11 11 11 4 Tetratricopeptide repeat TPR_8 PF13181.1 EXF83118.1 - 5.3e-13 47.7 3.0 0.0088 15.7 0.4 8.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_16 PF13432.1 EXF83118.1 - 1.8e-12 47.5 19.6 0.055 14.1 0.0 7.7 5 3 1 7 7 7 4 Tetratricopeptide repeat TPR_10 PF13374.1 EXF83118.1 - 4.2e-09 36.0 5.6 4.6 7.3 0.0 8.1 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.1 EXF83118.1 - 8.1e-07 28.3 19.3 1.9 8.4 0.1 8.9 10 0 0 10 10 9 1 Tetratricopeptide repeat TPR_6 PF13174.1 EXF83118.1 - 8.3e-06 25.9 11.7 0.63 10.6 0.1 7.7 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_17 PF13431.1 EXF83118.1 - 3.7e-05 23.5 6.1 11 6.5 0.0 8.0 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_4 PF07721.9 EXF83118.1 - 0.00038 20.6 3.2 1.8 9.2 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_15 PF13429.1 EXF83118.1 - 0.00051 19.2 8.1 0.066 12.2 0.0 5.5 3 2 1 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 EXF83118.1 - 0.00063 19.5 7.4 11 5.9 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Coatomer_E PF04733.9 EXF83118.1 - 0.019 14.1 0.3 16 4.5 0.0 3.8 3 1 0 4 4 4 0 Coatomer epsilon subunit OprD PF03573.8 EXF83119.1 - 0.083 11.6 0.6 0.11 11.2 0.4 1.1 1 0 0 1 1 1 0 outer membrane porin, OprD family DUF1757 PF08560.5 EXF83119.1 - 0.58 9.8 2.7 0.98 9.0 1.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1757) HET PF06985.6 EXF83120.1 - 5.9e-20 71.8 0.0 1.4e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) AMP-binding PF00501.23 EXF83121.1 - 8.1e-49 166.1 0.0 1.3e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme End3 PF12761.2 EXF83122.1 - 0.1 12.2 4.7 0.21 11.1 3.3 1.5 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 APG6 PF04111.7 EXF83122.1 - 2.2 7.2 9.9 2.1 7.3 5.5 1.8 2 0 0 2 2 2 0 Autophagy protein Apg6 zf-CCHC_6 PF15288.1 EXF83123.1 - 0.044 13.4 3.6 0.085 12.5 2.2 1.7 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.1 EXF83123.1 - 0.24 11.0 2.9 0.57 9.9 2.0 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.18 EXF83123.1 - 0.28 11.1 2.9 0.54 10.2 2.0 1.5 1 0 0 1 1 1 0 Zinc knuckle SlyX PF04102.7 EXF83125.1 - 0.2 12.0 4.6 0.27 11.6 0.2 3.4 2 2 1 3 3 3 0 SlyX Fib_alpha PF08702.5 EXF83125.1 - 4.1 7.5 9.5 1.1 9.3 1.0 2.6 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Fungal_trans_2 PF11951.3 EXF83126.1 - 2.7e-41 141.4 0.3 5.3e-41 140.4 0.2 1.4 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF83126.1 - 5.3e-10 39.0 12.1 9.4e-10 38.2 8.4 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Methyltransf_23 PF13489.1 EXF83127.1 - 7.3e-23 81.0 0.0 1.1e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF83127.1 - 1.6e-09 38.2 0.1 1.9e-08 34.8 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF83127.1 - 4.9e-07 30.1 0.0 2.3e-06 27.9 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF83127.1 - 1.8e-06 28.3 0.0 4.2e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF83127.1 - 4.6e-06 26.2 0.0 1.6e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF83127.1 - 0.0022 18.2 0.0 0.0047 17.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EXF83127.1 - 0.08 12.0 0.0 0.19 10.7 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_4 PF02390.12 EXF83127.1 - 0.1 11.6 0.0 0.33 9.9 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase MTS PF05175.9 EXF83127.1 - 0.12 11.7 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_16 PF10294.4 EXF83127.1 - 0.19 11.1 0.0 0.3 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Fungal_trans PF04082.13 EXF83128.1 - 1.2e-39 135.7 1.0 1.2e-39 135.7 0.7 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF83128.1 - 5e-08 32.7 9.6 8.7e-08 31.9 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain FMO-like PF00743.14 EXF83130.1 - 1.3e-40 139.1 0.0 1.6e-23 82.7 0.0 3.3 3 1 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EXF83130.1 - 1.3e-16 61.3 0.0 8.8e-16 58.5 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF83130.1 - 6.8e-13 48.6 3.0 1.3e-09 38.0 0.0 4.3 3 2 1 4 4 4 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EXF83130.1 - 9.8e-10 38.6 0.1 1.1e-05 25.4 0.0 2.9 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF83130.1 - 2.9e-09 36.3 0.6 6.6e-08 31.8 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EXF83130.1 - 5.6e-09 35.8 0.0 1.4e-07 31.4 0.0 2.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF83130.1 - 1.4e-08 34.0 0.0 2.4e-05 23.3 0.0 3.7 4 0 0 4 4 4 1 FAD dependent oxidoreductase Thi4 PF01946.12 EXF83130.1 - 7e-08 31.8 0.1 0.00011 21.3 0.1 2.2 2 0 0 2 2 2 2 Thi4 family FAD_binding_3 PF01494.14 EXF83130.1 - 2e-05 23.8 0.1 0.0024 17.0 0.0 2.3 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EXF83130.1 - 2.8e-05 22.8 0.1 0.034 12.6 0.4 2.5 3 0 0 3 3 3 2 HI0933-like protein Pyr_redox PF00070.22 EXF83130.1 - 8.3e-05 22.9 0.1 0.19 12.1 0.2 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EXF83130.1 - 0.00067 18.8 0.1 0.0022 17.1 0.0 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EXF83130.1 - 0.0011 17.8 0.3 0.053 12.3 0.1 2.6 3 0 0 3 3 3 1 FAD binding domain Shikimate_DH PF01488.15 EXF83130.1 - 0.0015 18.6 0.0 0.14 12.2 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EXF83130.1 - 0.0018 17.4 0.0 0.28 10.3 0.0 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EXF83130.1 - 0.0068 16.1 0.1 0.15 11.7 0.1 2.2 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 EXF83130.1 - 0.014 15.4 0.1 0.25 11.3 0.0 2.3 2 0 0 2 2 2 0 TrkA-N domain Lycopene_cycl PF05834.7 EXF83130.1 - 0.026 13.4 0.0 3.5 6.4 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 EXF83130.1 - 0.028 14.6 0.0 6.1 7.1 0.0 2.5 2 0 0 2 2 2 0 Putative NAD(P)-binding IlvN PF07991.7 EXF83130.1 - 0.036 13.4 0.0 0.66 9.3 0.0 2.2 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, catalytic domain CPSase_L_chain PF00289.17 EXF83130.1 - 0.058 13.5 0.0 3.7 7.7 0.0 2.4 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain FAD_oxidored PF12831.2 EXF83130.1 - 0.089 11.8 0.1 0.18 10.8 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase ThiF PF00899.16 EXF83130.1 - 0.091 12.5 0.1 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 ThiF family DJ-1_PfpI PF01965.19 EXF83130.1 - 0.096 12.1 0.0 11 5.4 0.0 2.5 2 0 0 2 2 2 0 DJ-1/PfpI family GIDA PF01134.17 EXF83130.1 - 0.16 10.7 0.1 5 5.8 0.2 2.3 3 0 0 3 3 3 0 Glucose inhibited division protein A GAS2 PF02187.12 EXF83131.1 - 5.7e-05 22.8 0.0 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Malic_M PF03949.10 EXF83132.1 - 6.7e-87 291.2 0.0 9.2e-87 290.8 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EXF83132.1 - 3.2e-71 238.6 0.0 5.5e-71 237.9 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain zf-RING_2 PF13639.1 EXF83133.1 - 5.8e-14 51.6 4.6 9.8e-14 50.9 3.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EXF83133.1 - 1.1e-07 31.8 0.4 2.2e-07 30.9 0.3 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EXF83133.1 - 9.1e-07 28.4 3.2 1.4e-06 27.8 2.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EXF83133.1 - 3.2e-06 27.0 5.1 4.9e-06 26.4 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EXF83133.1 - 6.8e-06 25.7 2.4 1.1e-05 25.0 1.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EXF83133.1 - 7.8e-05 22.2 2.3 0.00014 21.4 1.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EXF83133.1 - 0.0034 17.1 1.2 0.0065 16.2 0.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EXF83133.1 - 0.021 14.3 2.1 0.037 13.6 1.4 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.6 EXF83133.1 - 0.13 12.2 3.2 0.21 11.5 2.2 1.3 1 0 0 1 1 1 0 RING-like domain zf-RING_6 PF14835.1 EXF83133.1 - 0.38 10.5 2.2 0.76 9.5 1.5 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein PHD PF00628.24 EXF83133.1 - 0.43 10.3 2.6 0.79 9.4 1.8 1.5 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.1 EXF83133.1 - 1.6 8.5 3.7 27 4.5 3.4 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 FANCL_C PF11793.3 EXF83133.1 - 2.2 8.3 4.2 13 5.8 2.9 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain DUF3602 PF12223.3 EXF83134.1 - 7.5e-15 55.0 14.4 8.6e-14 51.6 0.8 3.1 1 1 2 3 3 3 3 Protein of unknown function (DUF3602) DUF4510 PF14971.1 EXF83134.1 - 0.042 14.0 1.4 1.1 9.3 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4510) URO-D PF01208.12 EXF83135.1 - 9.2e-119 396.3 0.0 1e-118 396.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Fungal_trans PF04082.13 EXF83137.1 - 8.4e-11 41.2 0.0 1.4e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF83137.1 - 2.5e-08 33.7 9.1 4e-08 33.0 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 EXF83139.1 - 8.9e-49 166.2 0.0 1.2e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EXF83140.1 - 1.6e-20 73.0 0.0 2.9e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 EXF83141.1 - 2.8e-26 92.4 0.1 5.3e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF83141.1 - 3.2e-10 39.9 0.0 7.5e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EXF83141.1 - 1.1e-06 28.0 0.1 2.1e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) adh_short_C2 PF13561.1 EXF83141.1 - 2.8e-05 24.0 0.0 3.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 EXF83141.1 - 0.00043 19.0 0.0 0.0007 18.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EXF83141.1 - 0.0019 17.7 0.0 0.0028 17.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Abhydrolase_3 PF07859.8 EXF83142.1 - 1.1e-20 74.1 0.7 2.3e-20 73.0 0.5 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EXF83142.1 - 1e-14 54.0 0.0 1.2e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EXF83142.1 - 0.033 13.9 0.1 0.067 12.9 0.1 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF83142.1 - 0.035 13.3 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ammonium_transp PF00909.16 EXF83143.1 - 2.4e-117 391.8 30.9 2.7e-117 391.6 21.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF2207 PF09972.4 EXF83143.1 - 4.8 5.6 7.0 6.6 5.1 0.4 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) CRT10 PF08728.5 EXF83144.1 - 1.1e-18 66.6 0.0 1.9e-15 55.9 0.0 2.1 2 0 0 2 2 2 2 CRT10 CAP_N PF01213.14 EXF83144.1 - 0.57 9.4 7.8 0.9 8.7 5.4 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 EXF83144.1 - 2.6 7.3 5.5 4.8 6.4 3.8 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Cellulase PF00150.13 EXF83145.1 - 1.4e-35 122.8 0.1 1.7e-35 122.6 0.1 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) 7tm_2 PF00002.19 EXF83146.1 - 6.4e-05 22.1 10.1 6.4e-05 22.1 7.0 1.7 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) Vma12 PF11712.3 EXF83146.1 - 0.25 11.0 3.9 0.79 9.4 0.2 3.0 3 0 0 3 3 3 0 Endoplasmic reticulum-based factor for assembly of V-ATPase HlyIII PF03006.15 EXF83147.1 - 3.2e-57 193.4 19.2 3.9e-57 193.1 13.3 1.1 1 0 0 1 1 1 1 Haemolysin-III related Polysacc_synt_C PF14667.1 EXF83147.1 - 5.8 6.7 15.5 0.18 11.6 3.9 2.5 1 1 2 3 3 3 0 Polysaccharide biosynthesis C-terminal domain FimP PF09766.4 EXF83148.1 - 1e-26 93.8 6.9 1.4e-26 93.3 4.8 1.2 1 0 0 1 1 1 1 Fms-interacting protein K-box PF01486.12 EXF83148.1 - 0.014 15.1 0.9 0.014 15.1 0.6 2.7 2 1 2 4 4 4 0 K-box region DUF1640 PF07798.6 EXF83148.1 - 0.48 10.4 4.2 0.42 10.6 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) CENP-F_leu_zip PF10473.4 EXF83148.1 - 0.59 9.9 8.4 0.62 9.9 1.2 2.3 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4200 PF13863.1 EXF83148.1 - 0.92 9.4 15.3 0.05 13.5 1.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Cortex-I_coil PF09304.5 EXF83148.1 - 1.1 9.3 12.2 0.47 10.5 1.4 2.8 2 1 1 3 3 3 0 Cortexillin I, coiled coil DUF2203 PF09969.4 EXF83148.1 - 1.2 9.3 4.1 0.82 9.9 0.4 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) YscO PF07321.7 EXF83148.1 - 2.9 7.7 16.8 4.4 7.0 1.3 3.1 2 1 1 3 3 3 0 Type III secretion protein YscO Glyco_trans_2_3 PF13632.1 EXF83149.1 - 3.6e-17 62.7 0.5 7.7e-17 61.6 0.3 1.6 1 0 0 1 1 1 1 Glycosyl transferase family group 2 FKBP_C PF00254.23 EXF83150.1 - 9.3e-31 105.7 0.4 4.9e-30 103.3 0.0 2.3 2 1 1 3 3 3 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2933 PF11666.3 EXF83151.1 - 2.5 7.7 5.4 0.37 10.3 1.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2933) Pkinase PF00069.20 EXF83152.1 - 8.3e-38 130.0 0.0 2.3e-32 112.2 0.0 2.5 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EXF83152.1 - 3.1e-15 55.9 0.0 6.2e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3905 PF13045.1 EXF83152.1 - 0.025 14.3 0.9 0.16 11.7 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3905) Kinase-like PF14531.1 EXF83152.1 - 0.15 11.0 0.0 0.35 9.7 0.0 1.5 2 0 0 2 2 2 0 Kinase-like Exo_endo_phos PF03372.18 EXF83153.1 - 1e-22 81.2 0.3 1.4e-22 80.8 0.2 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FA_desaturase PF00487.19 EXF83153.1 - 0.044 13.2 6.6 0.016 14.6 2.3 1.9 2 1 0 2 2 2 0 Fatty acid desaturase WD40 PF00400.27 EXF83154.1 - 2.3e-55 182.6 20.3 2.7e-12 46.0 0.3 8.0 7 2 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EXF83154.1 - 3.1e-05 22.3 7.3 0.002 16.3 0.0 4.1 4 2 1 5 5 5 2 Nucleoporin Nup120/160 eIF2A PF08662.6 EXF83154.1 - 8.2e-05 22.4 0.0 0.013 15.1 0.0 2.7 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EXF83154.1 - 0.00084 18.1 0.3 0.12 11.1 0.0 3.4 2 2 2 4 4 4 1 Nup133 N terminal like Cytochrom_D1 PF02239.11 EXF83154.1 - 0.00099 17.5 0.0 0.02 13.2 0.0 2.4 2 1 0 2 2 2 1 Cytochrome D1 heme domain VID27 PF08553.5 EXF83154.1 - 0.038 12.2 5.9 9.2 4.3 0.0 4.7 4 1 0 5 5 5 0 VID27 cytoplasmic protein DUF3312 PF11768.3 EXF83154.1 - 0.074 11.2 0.0 0.32 9.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3312) Med3 PF11593.3 EXF83154.1 - 0.092 11.9 0.0 0.092 11.9 0.0 2.2 1 1 1 2 2 2 0 Mediator complex subunit 3 fungal BTV_NS2 PF04514.7 EXF83154.1 - 4.6 6.0 9.2 7 5.4 6.4 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 zf-UBR PF02207.15 EXF83155.1 - 4.1e-18 64.8 12.1 1e-17 63.6 8.4 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) ClpS PF02617.12 EXF83155.1 - 3.6e-08 33.0 0.0 9.9e-08 31.6 0.0 1.7 1 0 0 1 1 1 1 ATP-dependent Clp protease adaptor protein ClpS zf-RING_2 PF13639.1 EXF83155.1 - 0.0014 18.3 3.2 0.0014 18.3 2.2 4.3 4 1 1 5 5 5 1 Ring finger domain DUF2067 PF09840.4 EXF83155.1 - 0.095 12.1 1.6 0.22 11.0 0.0 2.3 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2067) FBPase PF00316.15 EXF83155.1 - 0.26 10.0 0.0 0.47 9.2 0.0 1.3 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase WD40 PF00400.27 EXF83156.1 - 1.1e-19 69.4 17.2 2.8e-08 33.3 0.0 6.3 8 0 0 8 8 8 4 WD domain, G-beta repeat Rax2 PF12768.2 EXF83156.1 - 0.0049 16.1 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Cortical protein marker for cell polarity Gmad1 PF10647.4 EXF83156.1 - 0.084 12.2 0.7 4.5 6.6 0.0 2.6 2 1 1 3 3 3 0 Lipoprotein LpqB beta-propeller domain RRM_5 PF13893.1 EXF83157.1 - 1.7e-11 43.7 0.0 2.7e-11 43.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EXF83157.1 - 1.9e-09 37.0 0.0 5.3e-09 35.5 0.0 1.8 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF83157.1 - 1.6e-07 31.2 0.0 3.4e-07 30.1 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 EXF83157.1 - 0.00044 19.8 0.0 0.0007 19.2 0.0 1.3 1 0 0 1 1 1 1 Calcipressin Limkain-b1 PF11608.3 EXF83157.1 - 0.0073 16.0 0.4 0.018 14.8 0.0 1.7 2 0 0 2 2 2 1 Limkain b1 bPH_2 PF03703.9 EXF83157.1 - 0.13 12.3 0.0 18 5.4 0.0 2.3 2 1 0 2 2 2 0 Bacterial PH domain MSP1_C PF07462.6 EXF83157.1 - 6.5 5.0 5.9 8.1 4.6 4.1 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus Autophagy_act_C PF03987.10 EXF83158.1 - 4.7e-11 42.6 0.0 8e-11 41.9 0.0 1.4 1 1 0 1 1 1 1 Autophagocytosis associated protein, active-site domain 2-oxoacid_dh PF00198.18 EXF83159.1 - 1.9e-77 259.6 0.1 2.6e-77 259.2 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EXF83159.1 - 1.4e-18 66.2 4.0 2.5e-18 65.4 2.8 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 EXF83159.1 - 0.00083 18.6 4.3 0.0021 17.2 1.0 2.3 1 1 2 3 3 3 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 EXF83159.1 - 0.0036 16.9 1.0 0.071 12.7 0.1 2.3 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.1 EXF83159.1 - 0.025 14.8 0.4 0.086 13.1 0.3 1.8 1 1 0 1 1 1 0 HlyD family secretion protein RnfC_N PF13375.1 EXF83159.1 - 0.059 13.1 0.7 2.5 7.8 0.0 2.8 1 1 1 2 2 2 0 RnfC Barrel sandwich hybrid domain Trypan_PARP PF05887.6 EXF83159.1 - 0.29 10.9 19.4 0.5 10.1 13.4 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MSA-2c PF12238.3 EXF83159.1 - 7.6 6.1 9.8 14 5.2 6.8 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c Glyco_hydro_47 PF01532.15 EXF83160.1 - 3.4e-167 556.6 0.0 4.6e-167 556.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 DUF4038 PF13204.1 EXF83160.1 - 0.0071 15.7 0.1 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) AA_permease PF00324.16 EXF83161.1 - 5.2e-137 457.0 36.9 6.4e-137 456.7 25.6 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF83161.1 - 3.1e-41 141.3 32.7 4.3e-41 140.8 22.7 1.1 1 0 0 1 1 1 1 Amino acid permease SnoaL_2 PF12680.2 EXF83162.1 - 0.094 13.1 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain adh_short PF00106.20 EXF83163.1 - 3.7e-28 98.5 0.0 4.9e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF83163.1 - 1.8e-26 93.3 0.0 2.2e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF83163.1 - 1e-11 44.8 0.0 1.3e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF83163.1 - 0.0025 17.3 0.0 0.0034 16.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EXF83163.1 - 0.011 14.8 0.0 0.014 14.5 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Eno-Rase_NADH_b PF12242.3 EXF83163.1 - 0.055 13.2 0.1 0.12 12.1 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Cas_APE2256 PF09651.5 EXF83163.1 - 0.1 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) SNARE_assoc PF09335.6 EXF83165.1 - 0.54 10.4 10.2 0.25 11.5 1.7 3.2 1 1 0 2 2 2 0 SNARE associated Golgi protein SWIM PF04434.12 EXF83167.1 - 0.00037 19.9 0.1 0.00074 18.9 0.1 1.4 1 0 0 1 1 1 1 SWIM zinc finger Pkinase PF00069.20 EXF83168.1 - 0.00015 21.0 0.4 0.00035 19.7 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF83168.1 - 0.0018 17.3 0.2 0.076 12.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase TauD PF02668.11 EXF83171.1 - 1.7e-21 77.0 0.6 2.3e-21 76.6 0.4 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CsiD PF08943.5 EXF83171.1 - 0.04 12.7 0.1 0.066 12.0 0.1 1.2 1 0 0 1 1 1 0 CsiD His_Phos_2 PF00328.17 EXF83173.1 - 6.1e-43 147.4 0.0 7.2e-43 147.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Sulfate_transp PF00916.15 EXF83174.1 - 8.8e-72 241.4 15.7 1.6e-71 240.6 10.9 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EXF83174.1 - 1.2e-31 108.2 2.6 1.2e-31 108.2 1.8 3.2 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EXF83174.1 - 5.9e-09 35.3 0.0 1.2e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain RabGAP-TBC PF00566.13 EXF83175.1 - 1.8e-31 109.2 0.0 6.5e-26 91.1 0.0 2.2 2 0 0 2 2 2 2 Rab-GTPase-TBC domain DUF4072 PF13284.1 EXF83175.1 - 0.048 13.8 2.4 0.23 11.6 0.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4072) zf-H2C2_2 PF13465.1 EXF83176.1 - 4e-14 52.0 18.7 6.3e-08 32.5 1.8 3.5 3 0 0 3 3 3 3 Zinc-finger double domain zf-C2H2 PF00096.21 EXF83176.1 - 4.5e-10 39.2 23.3 0.0036 17.5 2.6 3.5 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF83176.1 - 8.4e-08 32.0 23.2 0.018 15.3 4.2 3.7 4 0 0 4 4 3 3 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EXF83176.1 - 0.0049 16.7 12.2 0.39 10.6 0.0 3.5 3 0 0 3 3 3 2 C2H2-type zinc finger Macoilin PF09726.4 EXF83176.1 - 0.11 10.7 0.7 0.19 9.9 0.5 1.3 1 0 0 1 1 1 0 Transmembrane protein LPP PF04728.8 EXF83176.1 - 0.13 12.0 0.2 0.42 10.4 0.1 1.8 1 1 1 2 2 2 0 Lipoprotein leucine-zipper zf-Di19 PF05605.7 EXF83176.1 - 0.37 10.9 11.4 1.6 8.9 4.4 2.3 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_jaz PF12171.3 EXF83176.1 - 0.43 10.7 16.5 1.8 8.7 0.2 4.2 4 1 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf-CHY PF05495.7 EXF83176.1 - 0.52 10.5 8.0 1 9.5 5.5 1.5 1 0 0 1 1 1 0 CHY zinc finger Zn-ribbon_8 PF09723.5 EXF83176.1 - 0.64 10.0 8.5 9.1 6.3 2.2 2.9 2 1 0 2 2 2 0 Zinc ribbon domain zinc-ribbons_6 PF07191.7 EXF83176.1 - 1.3 8.9 4.9 3.4 7.5 1.5 2.3 2 0 0 2 2 2 0 zinc-ribbons zf-C2HC_2 PF13913.1 EXF83176.1 - 1.8 8.3 7.2 0.082 12.6 0.4 2.2 2 0 0 2 2 2 0 zinc-finger of a C2HC-type DZR PF12773.2 EXF83176.1 - 2.5 7.9 6.8 18 5.2 4.7 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-CHCC PF10276.4 EXF83176.1 - 3.3 7.6 5.3 15 5.5 0.0 2.9 3 0 0 3 3 3 0 Zinc-finger domain zf-RING_3 PF14369.1 EXF83176.1 - 6.3 6.8 8.2 32 4.6 1.6 3.1 2 1 1 3 3 3 0 zinc-finger SUN PF03856.8 EXF83177.1 - 6.1e-78 261.5 13.3 8.6e-78 261.0 9.2 1.1 1 0 0 1 1 1 1 Beta-glucosidase (SUN family) PLRV_ORF5 PF01690.12 EXF83177.1 - 1.1 8.3 16.0 1.7 7.6 11.1 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein MFS_1 PF07690.11 EXF83178.1 - 2e-14 53.1 10.9 2e-14 53.1 7.5 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily DUF2681 PF10883.3 EXF83178.1 - 2.7 8.2 5.6 0.7 10.1 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2681) Hist_deacetyl PF00850.14 EXF83179.1 - 6.9e-77 258.7 0.0 2.5e-76 256.9 0.0 1.9 2 0 0 2 2 2 1 Histone deacetylase domain Glyco_hydro_114 PF03537.8 EXF83179.1 - 1.9e-15 56.3 0.1 5.4e-15 54.9 0.0 1.8 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 ING PF12998.2 EXF83180.1 - 5.4e-24 84.4 2.6 7.9e-24 83.9 1.8 1.2 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EXF83180.1 - 8.3e-08 31.7 9.3 8.3e-08 31.7 6.5 1.7 2 0 0 2 2 2 1 PHD-finger zf-RING-like PF08746.6 EXF83180.1 - 3.4 7.7 5.8 6.3 6.8 4.0 1.5 1 0 0 1 1 1 0 RING-like domain UDPGP PF01704.13 EXF83181.1 - 8e-11 41.0 0.2 8.4e-10 37.7 0.0 2.0 1 1 1 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase DUF3605 PF12239.3 EXF83182.1 - 8.3e-58 194.7 0.2 9.9e-58 194.4 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3605) FolB PF02152.13 EXF83183.1 - 7.7e-19 67.9 0.0 8e-13 48.5 0.0 2.3 2 0 0 2 2 2 2 Dihydroneopterin aldolase Peptidase_M1 PF01433.15 EXF83184.1 - 5.3e-139 463.6 0.0 1.1e-138 462.5 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 EXF83184.1 - 5.5e-83 278.8 1.3 9.2e-83 278.1 0.9 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EXF83184.1 - 2.2e-19 69.7 0.1 4.2e-19 68.8 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Enolase_C PF00113.17 EXF83185.1 - 3.4e-153 508.8 0.2 4.3e-153 508.4 0.1 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EXF83185.1 - 7.4e-59 197.4 0.3 1.3e-58 196.6 0.2 1.4 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE PF01188.16 EXF83185.1 - 0.048 14.1 0.0 0.12 12.8 0.0 1.8 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MAAL_C PF07476.6 EXF83185.1 - 0.051 12.5 0.3 0.6 8.9 0.1 2.4 3 0 0 3 3 3 0 Methylaspartate ammonia-lyase C-terminus PKD_channel PF08016.7 EXF83186.1 - 0.0017 16.8 6.2 0.092 11.1 0.7 2.2 2 0 0 2 2 2 2 Polycystin cation channel Glyco_hydro_67M PF07488.7 EXF83187.1 - 4e-144 479.5 0.0 5.4e-144 479.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 middle domain Glyco_hydro_67C PF07477.7 EXF83187.1 - 1e-94 316.1 1.7 1.5e-94 315.6 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 C-terminus Glyco_hydro_67N PF03648.9 EXF83187.1 - 1.1e-24 86.8 0.0 2.2e-24 85.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 67 N-terminus Glyco_hydro_20b PF02838.10 EXF83187.1 - 0.0013 19.2 0.1 0.0038 17.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Ribul_P_3_epim PF00834.14 EXF83187.1 - 0.048 12.7 0.0 0.11 11.6 0.0 1.5 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Methyltransf_26 PF13659.1 EXF83188.1 - 4.2e-19 68.7 0.2 5.6e-19 68.3 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF83188.1 - 0.02 14.2 0.2 0.064 12.6 0.2 1.8 1 1 0 1 1 1 0 Methyltransferase small domain Tyrosinase PF00264.15 EXF83189.1 - 1.4e-50 172.5 4.5 2.8e-50 171.5 3.1 1.5 1 0 0 1 1 1 1 Common central domain of tyrosinase LSM PF01423.17 EXF83189.1 - 4.7e-15 54.8 0.0 7.9e-15 54.1 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EXF83189.1 - 0.011 15.5 0.0 0.039 13.8 0.0 1.9 2 0 0 2 2 2 0 Ataxin 2 SM domain RNA_pol_Rpb2_6 PF00562.23 EXF83190.1 - 3.4e-113 378.2 0.0 4.5e-113 377.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EXF83190.1 - 8.4e-31 106.4 0.0 1.2e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EXF83190.1 - 1.8e-26 92.7 0.0 2.9e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.11 EXF83190.1 - 2.3e-25 88.1 0.0 6.5e-25 86.6 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpa2_4 PF06883.7 EXF83190.1 - 1.4e-22 79.4 0.0 2.9e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_7 PF04560.15 EXF83190.1 - 1.3e-14 54.2 0.0 7.4e-14 51.7 0.0 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.12 EXF83190.1 - 0.013 15.4 0.1 0.029 14.3 0.1 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 5 Rpr2 PF04032.11 EXF83190.1 - 0.064 13.1 0.7 0.13 12.0 0.5 1.5 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Arf PF00025.16 EXF83191.1 - 1.7e-44 151.1 0.1 2.1e-44 150.8 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EXF83191.1 - 7.9e-21 74.1 0.0 9.2e-21 73.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EXF83191.1 - 1e-11 45.3 0.0 1.8e-11 44.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EXF83191.1 - 9.4e-08 31.4 0.0 1.2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EXF83191.1 - 2.1e-06 26.7 0.1 3.2e-06 26.0 0.0 1.5 1 1 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.5 EXF83191.1 - 6.7e-06 25.4 0.0 8.2e-06 25.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EXF83191.1 - 1.9e-05 24.5 0.0 3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EXF83191.1 - 2.7e-05 23.6 0.0 0.00045 19.7 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EXF83191.1 - 0.0028 17.4 0.1 0.12 12.2 0.0 2.1 1 1 1 2 2 2 1 Dynamin family PduV-EutP PF10662.4 EXF83191.1 - 0.013 14.9 0.1 0.38 10.2 0.0 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EXF83191.1 - 0.039 13.2 0.4 0.089 12.0 0.3 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B ATP_bind_1 PF03029.12 EXF83191.1 - 0.065 12.7 0.0 0.11 11.9 0.0 1.4 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Glyco_transf_17 PF04724.8 EXF83192.1 - 2.5e-44 151.7 0.1 3.9e-44 151.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 17 Beta_elim_lyase PF01212.16 EXF83193.1 - 1.7e-68 230.8 0.0 2.1e-68 230.6 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EXF83193.1 - 4.3e-06 25.2 0.0 8.3e-06 24.3 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EXF83193.1 - 6.7e-06 25.2 0.0 8.5e-06 24.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EXF83193.1 - 0.0013 17.8 0.5 0.0038 16.3 0.4 1.8 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EXF83193.1 - 0.14 10.8 0.0 0.2 10.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Trehalase PF01204.13 EXF83194.1 - 3e-119 399.0 6.8 2.2e-118 396.1 4.7 1.9 1 1 0 1 1 1 1 Trehalase GDE_C PF06202.9 EXF83194.1 - 1.5e-05 23.8 0.0 0.00011 21.0 0.0 2.0 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase Mqo PF06039.10 EXF83194.1 - 0.12 10.5 0.0 0.2 9.8 0.0 1.2 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Band_7 PF01145.20 EXF83195.1 - 1.1e-23 84.0 2.2 2.2e-23 83.1 1.5 1.5 1 0 0 1 1 1 1 SPFH domain / Band 7 family ubiquitin PF00240.18 EXF83196.1 - 1.2e-17 63.0 0.1 5.4e-17 60.9 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EXF83196.1 - 3.3e-10 39.4 0.0 5.3e-10 38.8 0.0 1.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Elongin_A PF06881.6 EXF83197.1 - 6.7e-19 68.2 1.3 1.2e-18 67.4 0.9 1.5 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A Macoilin PF09726.4 EXF83197.1 - 7.8 4.6 8.7 11 4.1 6.0 1.3 1 0 0 1 1 1 0 Transmembrane protein TFIIF_beta PF02270.10 EXF83198.1 - 9.8e-62 209.2 3.7 1.2e-61 208.9 2.6 1.0 1 0 0 1 1 1 1 Transcription initiation factor IIF, beta subunit DUF2336 PF10098.4 EXF83198.1 - 0.36 10.0 5.5 0.058 12.6 0.6 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2336) HAD PF12710.2 EXF83199.1 - 4.3e-19 69.4 0.1 6.1e-19 68.9 0.1 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EXF83199.1 - 0.026 14.7 0.2 0.097 12.8 0.1 2.1 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase PTPA PF03095.10 EXF83203.1 - 7.8e-111 370.0 0.0 9.4e-111 369.7 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein RNase_PH PF01138.16 EXF83204.1 - 7.5e-14 52.1 0.0 1.4e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EXF83204.1 - 0.00016 21.5 0.1 0.00028 20.7 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 NAD_kinase PF01513.16 EXF83205.1 - 5.9e-74 248.4 0.0 7.8e-74 248.0 0.0 1.2 1 0 0 1 1 1 1 ATP-NAD kinase Homeobox PF00046.24 EXF83207.1 - 7.3e-13 47.9 1.0 1.4e-12 46.9 0.7 1.5 1 0 0 1 1 1 1 Homeobox domain Ras PF00071.17 EXF83208.1 - 4.1e-49 166.0 0.0 5e-49 165.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EXF83208.1 - 4.6e-15 56.1 0.0 8.9e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EXF83208.1 - 1.4e-10 40.6 0.0 1.8e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.17 EXF83208.1 - 0.0004 20.5 0.1 0.0024 18.0 0.1 2.1 1 1 0 1 1 1 1 RNA helicase Gtr1_RagA PF04670.7 EXF83208.1 - 0.0024 17.0 0.0 0.0032 16.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Pox_A32 PF04665.7 EXF83208.1 - 0.019 14.2 0.1 0.032 13.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.15 EXF83208.1 - 0.047 12.3 2.9 0.6 8.7 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit AAA_22 PF13401.1 EXF83208.1 - 0.054 13.6 0.3 0.22 11.6 0.1 2.2 2 1 0 2 2 2 0 AAA domain SRPRB PF09439.5 EXF83208.1 - 0.068 12.3 0.0 0.12 11.6 0.0 1.4 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_33 PF13671.1 EXF83208.1 - 0.077 12.8 0.1 0.15 11.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EXF83208.1 - 0.15 11.7 0.1 0.28 10.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 KaiC PF06745.8 EXF83208.1 - 0.16 11.0 0.2 0.25 10.4 0.1 1.2 1 0 0 1 1 1 0 KaiC Septin PF00735.13 EXF83208.1 - 0.2 10.6 0.6 0.31 9.9 0.0 1.6 2 0 0 2 2 2 0 Septin GRASP55_65 PF04495.9 EXF83209.1 - 1.8e-08 34.4 0.0 3.9e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EXF83209.1 - 3.3e-05 23.6 0.0 5.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.19 EXF83209.1 - 0.00075 19.6 0.0 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) HalX PF08663.5 EXF83209.1 - 0.041 13.8 0.2 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 HalX domain PWI PF01480.12 EXF83210.1 - 5.7e-11 42.3 0.1 9.5e-11 41.6 0.1 1.3 1 0 0 1 1 1 1 PWI domain F-box PF00646.28 EXF83211.1 - 0.011 15.3 0.0 0.028 14.1 0.0 1.7 1 0 0 1 1 1 0 F-box domain Dynamin_M PF01031.15 EXF83212.1 - 1.1e-112 375.6 0.0 2.7e-112 374.3 0.0 1.6 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EXF83212.1 - 3.8e-56 189.4 0.0 8.4e-56 188.3 0.0 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.13 EXF83212.1 - 7.1e-31 105.9 1.7 7.1e-31 105.9 1.2 2.2 3 0 0 3 3 3 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EXF83212.1 - 0.00099 19.0 0.0 0.0039 17.1 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EXF83212.1 - 0.013 16.0 0.0 0.044 14.2 0.0 1.9 2 0 0 2 2 2 0 Miro-like protein zf-CCHC_4 PF14392.1 EXF83212.1 - 0.13 11.9 0.1 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 Zinc knuckle CHCH PF06747.8 EXF83213.1 - 0.0032 17.3 0.2 0.0081 16.0 0.2 1.7 1 1 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EXF83213.1 - 0.013 15.5 1.8 0.045 13.7 1.2 1.8 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EXF83213.1 - 0.016 14.9 1.2 0.053 13.3 0.8 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.8 EXF83213.1 - 0.1 12.6 2.3 0.89 9.6 0.2 2.3 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) LIM PF00412.17 EXF83214.1 - 4.1e-24 84.4 23.4 1.1e-08 35.0 4.3 3.4 3 0 0 3 3 3 3 LIM domain Rad60-SLD PF11976.3 EXF83215.1 - 4.7e-20 71.0 0.2 5.9e-20 70.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EXF83215.1 - 6.8e-09 35.0 0.1 8.3e-09 34.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family HH_signal PF01085.13 EXF83215.1 - 0.017 14.6 0.0 0.018 14.5 0.0 1.1 1 0 0 1 1 1 0 Hedgehog amino-terminal signalling domain Nup84_Nup100 PF04121.8 EXF83216.1 - 2.9e-69 233.5 0.2 7e-68 228.9 0.2 2.7 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 Mod_r PF07200.8 EXF83217.1 - 3.3e-09 36.8 1.7 6.7e-09 35.8 1.1 1.4 1 1 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein FUSC PF04632.7 EXF83217.1 - 0.35 9.2 7.0 0.4 9.0 4.9 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family F-box PF00646.28 EXF83219.1 - 3.9e-09 35.9 0.6 1.3e-08 34.2 0.4 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EXF83219.1 - 1.5e-06 27.8 3.0 2.5e-06 27.1 0.2 2.8 4 0 0 4 4 4 1 F-box-like V-ATPase_C PF03223.10 EXF83221.1 - 8e-117 390.2 0.1 8.8e-117 390.1 0.1 1.0 1 0 0 1 1 1 1 V-ATPase subunit C APS_kinase PF01583.15 EXF83222.1 - 5.9e-72 240.4 0.0 8.6e-72 239.9 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase 4HBT PF03061.17 EXF83222.1 - 5.2e-10 39.3 0.0 1.1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Thioesterase superfamily AAA_33 PF13671.1 EXF83222.1 - 1.3e-06 28.3 0.0 2.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EXF83222.1 - 2.8e-05 24.8 0.0 5.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EXF83222.1 - 9.1e-05 22.7 0.0 0.00019 21.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EXF83222.1 - 0.0015 17.7 0.0 0.0023 17.1 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_16 PF13191.1 EXF83222.1 - 0.033 14.1 0.6 0.44 10.4 0.3 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EXF83222.1 - 0.057 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain PRK PF00485.13 EXF83222.1 - 0.13 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.7 EXF83222.1 - 0.15 11.1 0.1 0.42 9.6 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin RNA_pol_L_2 PF13656.1 EXF83222.1 - 0.15 11.4 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb3/Rpb11 dimerisation domain CBF PF03914.12 EXF83224.1 - 5.6e-42 142.9 0.4 1.7e-41 141.4 0.3 1.9 1 0 0 1 1 1 1 CBF/Mak21 family tRNA-synt_2b PF00587.20 EXF83225.1 - 2.9e-36 124.6 0.0 4.6e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EXF83225.1 - 6e-13 48.5 0.0 1.3e-12 47.4 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EXF83225.1 - 0.07 11.8 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II (D, K and N) Prefoldin PF02996.12 EXF83226.1 - 3.7e-13 49.1 0.1 4.9e-12 45.5 0.1 2.1 1 1 0 1 1 1 1 Prefoldin subunit Sec2p PF06428.6 EXF83226.1 - 0.0047 16.7 7.2 0.088 12.6 0.8 2.2 2 0 0 2 2 2 2 GDP/GTP exchange factor Sec2p Fzo_mitofusin PF04799.8 EXF83226.1 - 0.015 14.6 4.0 0.43 9.9 0.3 2.1 2 0 0 2 2 2 0 fzo-like conserved region CCDC155 PF14662.1 EXF83226.1 - 0.08 12.5 6.4 0.076 12.6 0.6 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 Cep57_MT_bd PF06657.8 EXF83226.1 - 0.096 12.6 0.7 0.096 12.6 0.5 1.7 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 DUF904 PF06005.7 EXF83226.1 - 0.1 12.9 5.8 4.4 7.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Trehalose_PPase PF02358.11 EXF83226.1 - 0.1 11.4 1.3 2.7 6.8 0.0 2.1 2 0 0 2 2 2 0 Trehalose-phosphatase Noelin-1 PF12308.3 EXF83226.1 - 0.81 9.5 4.3 3.3 7.5 0.5 2.1 2 0 0 2 2 2 0 Neurogenesis glycoprotein UPF0449 PF15136.1 EXF83226.1 - 1.5 9.0 4.4 19 5.5 0.2 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 UDG PF03167.14 EXF83227.1 - 0.00049 19.5 0.0 0.0012 18.3 0.0 1.6 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily Mito_carr PF00153.22 EXF83228.1 - 1.2e-61 204.4 0.4 1.6e-21 75.8 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein F-box-like PF12937.2 EXF83229.1 - 8.8e-10 38.1 0.0 1.9e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EXF83229.1 - 0.02 14.5 0.0 0.048 13.3 0.0 1.6 1 0 0 1 1 1 0 F-box domain adh_short PF00106.20 EXF83230.1 - 1e-24 87.3 3.4 3.1e-24 85.7 2.4 1.7 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF83230.1 - 1.9e-12 47.2 0.8 3.2e-12 46.4 0.6 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF83230.1 - 5.9e-11 42.6 0.0 7.8e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EXF83230.1 - 0.0015 18.0 0.3 0.0031 16.9 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF83230.1 - 0.0025 17.8 1.1 0.1 12.6 0.3 2.3 1 1 1 2 2 2 1 NADH(P)-binding NAD_binding_4 PF07993.7 EXF83230.1 - 0.024 13.5 1.0 0.13 11.1 0.4 2.0 1 1 1 2 2 2 0 Male sterility protein DUF1776 PF08643.5 EXF83230.1 - 0.11 11.5 0.0 0.17 11.0 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DivIVA PF05103.8 EXF83231.1 - 9.4 6.2 10.7 0.36 10.8 2.1 2.5 2 1 0 2 2 2 0 DivIVA protein DUF3112 PF11309.3 EXF83232.1 - 0.18 11.5 10.6 1.5 8.6 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3112) PDGLE PF13190.1 EXF83232.1 - 1.3 8.7 3.8 2.1 8.1 2.0 1.9 2 0 0 2 2 2 0 PDGLE domain MBOAT PF03062.14 EXF83233.1 - 2.1e-45 155.2 17.8 2.1e-45 155.2 12.3 2.2 2 1 1 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family Asn_synthase PF00733.16 EXF83234.1 - 6.2e-52 176.6 0.0 8.4e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EXF83234.1 - 8.1e-37 125.7 0.0 1.7e-36 124.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EXF83234.1 - 2e-33 115.1 0.0 5e-33 113.8 0.0 1.7 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EXF83234.1 - 2.4e-07 30.2 0.0 4.6e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EXF83234.1 - 0.0026 16.5 0.0 0.29 9.7 0.0 2.7 1 1 2 3 3 3 1 Glutamine amidotransferases class-II tRNA_Me_trans PF03054.11 EXF83234.1 - 0.022 13.3 0.0 0.034 12.7 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase NAD_synthase PF02540.12 EXF83234.1 - 0.029 13.2 0.0 0.045 12.6 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Amidohydro_2 PF04909.9 EXF83235.1 - 9e-22 77.9 0.1 1.4e-21 77.3 0.1 1.5 1 1 0 1 1 1 1 Amidohydrolase Spt5-NGN PF03439.8 EXF83235.1 - 0.12 12.1 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Early transcription elongation factor of RNA pol II, NGN section UxaC PF02614.9 EXF83235.1 - 0.17 10.4 0.1 0.26 9.8 0.1 1.3 1 0 0 1 1 1 0 Glucuronate isomerase PAM2 PF07145.10 EXF83236.1 - 0.0027 17.1 8.5 0.82 9.3 0.1 3.8 3 0 0 3 3 3 3 Ataxin-2 C-terminal region AIM24 PF01987.12 EXF83237.1 - 1.7e-52 177.9 0.4 2.2e-52 177.6 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial biogenesis AIM24 Aldedh PF00171.17 EXF83238.1 - 4.4e-12 45.0 11.0 1.3e-07 30.3 0.4 3.0 3 0 0 3 3 3 3 Aldehyde dehydrogenase family URO-D PF01208.12 EXF83238.1 - 0.053 12.4 0.0 0.24 10.2 0.0 1.8 1 1 1 2 2 2 0 Uroporphyrinogen decarboxylase (URO-D) F_actin_cap_B PF01115.12 EXF83238.1 - 0.18 11.0 0.2 0.64 9.1 0.0 1.8 2 0 0 2 2 2 0 F-actin capping protein, beta subunit MFS_1 PF07690.11 EXF83239.1 - 1.9e-43 148.5 41.9 1.9e-43 148.5 29.0 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF83239.1 - 7.8e-07 28.0 14.4 7.8e-07 28.0 9.9 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter IDO PF01231.13 EXF83240.1 - 3.3e-41 141.1 0.0 4.5e-41 140.6 0.0 1.1 1 0 0 1 1 1 1 Indoleamine 2,3-dioxygenase INO80_Ies4 PF08193.6 EXF83242.1 - 8.1e-65 218.9 19.8 2.8e-64 217.1 13.7 1.8 1 1 0 1 1 1 1 INO80 complex subunit Ies4 CLTH PF10607.4 EXF83243.1 - 6.7e-34 116.6 0.1 1.1e-33 115.9 0.0 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EXF83243.1 - 3.6e-25 88.4 0.2 6.2e-25 87.6 0.1 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 EXF83243.1 - 6e-06 25.8 0.5 1.4e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 LisH MFS_1 PF07690.11 EXF83244.1 - 3.5e-27 95.0 44.7 4.9e-21 74.8 20.8 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nodulin-like PF06813.8 EXF83244.1 - 0.0025 17.1 9.3 0.0039 16.4 4.1 2.1 1 1 1 2 2 2 1 Nodulin-like LAM_C PF12544.3 EXF83245.1 - 8.1e-05 22.6 0.1 0.0002 21.4 0.0 1.6 1 0 0 1 1 1 1 Lysine-2,3-aminomutase Sec34 PF04136.10 EXF83245.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Sec34-like family RNB PF00773.14 EXF83248.1 - 7.6e-57 193.0 0.0 1.1e-56 192.5 0.0 1.2 1 0 0 1 1 1 1 RNB domain Rhomboid PF01694.17 EXF83249.1 - 1.8e-19 70.2 20.1 7.5e-19 68.1 11.0 2.2 1 1 1 2 2 2 2 Rhomboid family Ycf1 PF05758.7 EXF83252.1 - 10 3.7 17.4 0.21 9.2 3.3 2.1 2 0 0 2 2 2 0 Ycf1 IU_nuc_hydro PF01156.14 EXF83253.1 - 3.9e-54 183.9 0.0 7.2e-42 143.6 0.0 2.1 2 0 0 2 2 2 2 Inosine-uridine preferring nucleoside hydrolase LSM PF01423.17 EXF83254.1 - 2.3e-15 55.8 0.0 3.3e-15 55.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain HECT_2 PF09814.4 EXF83256.1 - 2.1e-54 184.5 0.0 2.8e-54 184.1 0.0 1.2 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding DUF4653 PF15546.1 EXF83256.1 - 0.18 11.0 3.3 0.45 9.7 2.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) SR-25 PF10500.4 EXF83256.1 - 4 6.8 11.4 1.7 8.0 5.5 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Kelch_6 PF13964.1 EXF83257.1 - 1.1e-06 28.5 3.2 0.48 10.6 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Glycophorin_A PF01102.13 EXF83257.1 - 3.9e-05 23.4 2.2 0.00014 21.6 1.5 2.0 1 0 0 1 1 1 1 Glycophorin A Rifin_STEVOR PF02009.11 EXF83257.1 - 0.0009 18.9 0.4 0.0015 18.2 0.3 1.2 1 0 0 1 1 1 1 Rifin/stevor family TMEM154 PF15102.1 EXF83257.1 - 0.011 15.4 3.7 0.04 13.6 2.6 1.9 1 1 0 1 1 1 0 TMEM154 protein family Podoplanin PF05808.6 EXF83257.1 - 0.06 12.9 5.3 0.12 11.8 3.1 2.1 1 1 0 1 1 1 0 Podoplanin Macoilin PF09726.4 EXF83257.1 - 3.3 5.8 10.1 5 5.2 7.0 1.2 1 0 0 1 1 1 0 Transmembrane protein MtrF PF09472.5 EXF83257.1 - 3.7 6.8 5.4 6.8 6.0 3.7 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) RAP1 PF07218.6 EXF83257.1 - 8 4.4 19.0 12 3.8 13.2 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Defensin_big PF14862.1 EXF83258.1 - 0.057 13.4 0.9 1.4 9.0 0.1 2.2 2 0 0 2 2 2 0 Big defensin TAP_C PF03943.8 EXF83259.1 - 9.4e-14 50.5 0.1 1.6e-13 49.8 0.1 1.4 1 0 0 1 1 1 1 TAP C-terminal domain LRR_4 PF12799.2 EXF83259.1 - 1.7e-10 40.2 2.6 1.2e-05 24.7 0.1 2.9 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EXF83259.1 - 2.7e-06 27.0 2.5 0.00013 21.6 0.2 2.4 1 1 1 2 2 2 2 Leucine rich repeat NTF2 PF02136.15 EXF83259.1 - 8.6e-06 26.1 0.0 2.6e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain LRR_6 PF13516.1 EXF83259.1 - 0.00063 19.5 1.0 0.3 11.2 0.1 3.6 3 0 0 3 3 3 1 Leucine Rich repeat LRR_1 PF00560.28 EXF83259.1 - 0.00079 19.1 0.2 2.2 8.6 0.0 3.6 3 0 0 3 3 3 2 Leucine Rich Repeat LRR_7 PF13504.1 EXF83259.1 - 0.02 15.0 0.1 1.7 9.2 0.0 3.4 3 0 0 3 3 3 0 Leucine rich repeat DEAD PF00270.24 EXF83260.1 - 1e-21 77.1 0.0 1.2e-20 73.6 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase ResIII PF04851.10 EXF83260.1 - 1.4e-21 77.1 0.0 3.5e-21 75.8 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EXF83260.1 - 3.6e-20 71.6 0.0 9.9e-20 70.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.1 EXF83260.1 - 0.0018 18.4 0.0 0.012 15.7 0.0 2.3 1 1 1 2 2 2 1 AAA domain Fungal_trans PF04082.13 EXF83261.1 - 1.1e-13 50.6 0.0 1.9e-13 49.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF83261.1 - 4.1e-07 29.8 12.4 7e-07 29.0 8.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Dynactin PF12455.3 EXF83263.1 - 2.4e-90 302.1 8.1 2.4e-90 302.1 5.6 3.6 3 0 0 3 3 3 1 Dynein associated protein CAP_GLY PF01302.20 EXF83263.1 - 2.3e-21 75.2 0.2 3.8e-21 74.5 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain Tropomyosin_1 PF12718.2 EXF83263.1 - 0.0083 15.9 15.9 0.0083 15.9 11.0 6.8 4 1 3 7 7 7 1 Tropomyosin like Reo_sigmaC PF04582.7 EXF83263.1 - 7.3 5.6 29.8 0.12 11.4 2.5 4.7 2 2 3 5 5 5 0 Reovirus sigma C capsid protein HMG_box PF00505.14 EXF83264.1 - 5.3e-11 42.6 0.0 1.3e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box DUF1272 PF06906.6 EXF83264.1 - 0.13 12.1 0.2 0.26 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) TIP49 PF06068.8 EXF83265.1 - 1.3e-187 623.4 0.2 1.5e-187 623.2 0.2 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EXF83265.1 - 8.9e-12 45.3 0.2 3.4e-07 30.5 0.1 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EXF83265.1 - 1.9e-09 36.8 2.1 1.6e-06 27.3 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EXF83265.1 - 2.8e-05 23.7 1.1 0.00012 21.7 0.2 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EXF83265.1 - 0.00014 22.0 0.2 0.71 10.0 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EXF83265.1 - 0.00034 20.6 0.0 0.1 12.5 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 EXF83265.1 - 0.00056 19.9 0.1 0.0011 18.9 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EXF83265.1 - 0.0042 16.4 0.0 0.019 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EXF83265.1 - 0.0066 16.1 0.1 0.17 11.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EXF83265.1 - 0.0089 15.1 0.3 0.022 13.8 0.2 1.6 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.16 EXF83265.1 - 0.017 14.2 0.2 0.5 9.4 0.1 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EXF83265.1 - 0.027 13.9 0.2 0.06 12.7 0.2 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 EXF83265.1 - 0.033 13.6 0.1 1.7 8.1 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF2075 PF09848.4 EXF83265.1 - 0.035 13.0 0.1 0.098 11.6 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 EXF83265.1 - 0.042 14.1 0.1 0.096 12.9 0.1 1.8 1 0 0 1 1 1 0 AAA domain DnaB_C PF03796.10 EXF83265.1 - 0.048 12.5 0.0 0.095 11.5 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_17 PF13207.1 EXF83265.1 - 0.11 13.2 0.1 0.28 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EXF83265.1 - 0.11 12.3 0.0 0.43 10.4 0.0 1.9 2 0 0 2 2 2 0 AAA domain EamA PF00892.15 EXF83266.1 - 1.7e-20 73.3 18.8 1.8e-11 44.1 1.6 2.6 2 2 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EXF83266.1 - 6.9e-05 21.9 2.1 6.9e-05 21.9 1.4 2.2 2 1 0 2 2 2 1 UAA transporter family EmrE PF13536.1 EXF83266.1 - 0.0014 18.7 4.2 0.0014 18.7 2.9 3.5 2 1 1 3 3 3 1 Multidrug resistance efflux transporter TPT PF03151.11 EXF83266.1 - 2 8.0 16.2 1.7 8.3 2.4 3.2 2 2 0 2 2 2 0 Triose-phosphate Transporter family TFIID-18kDa PF02269.11 EXF83267.1 - 2.3e-18 65.7 0.0 3.6e-18 65.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit Bromo_TP PF07524.8 EXF83267.1 - 3.1e-05 23.6 0.0 6e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.1 EXF83267.1 - 0.0022 18.1 0.0 0.0039 17.3 0.0 1.4 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EXF83267.1 - 0.0043 17.0 1.0 0.02 14.9 0.0 2.2 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Transcrip_reg PF01709.15 EXF83267.1 - 0.0057 15.8 3.0 0.0074 15.4 2.1 1.1 1 0 0 1 1 1 1 Transcriptional regulator Histone PF00125.19 EXF83267.1 - 0.079 13.0 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF1242 PF06842.7 EXF83268.1 - 9.4e-20 69.8 0.4 1.2e-19 69.4 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) Tcp11 PF05794.8 EXF83269.1 - 1.8e-80 270.8 0.0 4.9e-77 259.5 0.2 2.1 2 0 0 2 2 2 2 T-complex protein 11 DUF3584 PF12128.3 EXF83269.1 - 0.079 10.2 0.1 0.12 9.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Uds1 PF15456.1 EXF83270.1 - 1.3e-40 138.2 9.4 1.3e-40 138.2 6.5 7.7 3 2 5 8 8 8 1 Up-regulated During Septation HR1 PF02185.11 EXF83270.1 - 6.2e-05 22.6 4.3 6.2e-05 22.6 3.0 10.9 6 3 4 10 10 10 2 Hr1 repeat APG6 PF04111.7 EXF83270.1 - 0.0017 17.4 2.0 0.0017 17.4 1.4 7.0 3 1 4 8 8 8 1 Autophagy protein Apg6 Filament PF00038.16 EXF83270.1 - 0.003 17.0 5.3 0.003 17.0 3.7 7.2 5 2 1 6 6 6 4 Intermediate filament protein Rootletin PF15035.1 EXF83270.1 - 0.0041 17.1 4.0 0.0041 17.1 2.7 6.8 4 1 3 7 7 7 1 Ciliary rootlet component, centrosome cohesion IncA PF04156.9 EXF83270.1 - 0.005 16.4 3.4 0.005 16.4 2.4 8.3 4 2 2 6 6 6 2 IncA protein TMF_DNA_bd PF12329.3 EXF83270.1 - 0.012 15.3 8.5 0.012 15.3 5.9 11.4 8 3 4 12 12 12 0 TATA element modulatory factor 1 DNA binding SlyX PF04102.7 EXF83270.1 - 0.015 15.6 2.8 0.015 15.6 1.9 10.6 9 2 3 12 12 12 0 SlyX Adeno_E4 PF05385.6 EXF83270.1 - 0.046 13.6 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 Mastadenovirus early E4 13 kDa protein DUF1751 PF08551.5 EXF83271.1 - 3.3e-05 24.1 0.2 5.7e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EXF83271.1 - 0.032 14.2 2.1 0.061 13.3 1.5 1.5 1 1 0 1 1 1 0 Rhomboid family Prenyltransf PF01255.14 EXF83272.1 - 2e-88 295.2 0.0 2.8e-88 294.7 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase PHD PF00628.24 EXF83273.1 - 3.6e-09 36.1 7.2 5.8e-09 35.5 5.0 1.3 1 0 0 1 1 1 1 PHD-finger ING PF12998.2 EXF83273.1 - 1e-06 28.9 0.0 0.0043 17.3 0.0 2.5 2 0 0 2 2 2 2 Inhibitor of growth proteins N-terminal histone-binding LRR_6 PF13516.1 EXF83274.1 - 0.00064 19.5 0.0 0.14 12.2 0.0 3.9 4 0 0 4 4 4 1 Leucine Rich repeat LRR_4 PF12799.2 EXF83274.1 - 0.0019 17.7 0.6 0.14 11.8 0.1 3.4 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EXF83274.1 - 0.0028 17.3 2.9 1 9.1 0.1 4.1 4 0 0 4 4 4 2 Leucine rich repeat F-box-like PF12937.2 EXF83274.1 - 0.1 12.3 0.1 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 F-box-like GRAB PF10375.4 EXF83276.1 - 6.1e-09 35.1 0.1 1.4e-08 34.0 0.1 1.7 1 0 0 1 1 1 1 GRIP-related Arf-binding domain Filament PF00038.16 EXF83276.1 - 3.4e-05 23.4 54.8 0.012 15.1 19.6 2.1 1 1 1 2 2 2 2 Intermediate filament protein HALZ PF02183.13 EXF83276.1 - 0.0056 16.3 0.8 0.0056 16.3 0.5 5.7 6 1 1 7 7 6 1 Homeobox associated leucine zipper CENP-F_leu_zip PF10473.4 EXF83276.1 - 0.013 15.3 28.8 0.013 15.3 20.0 3.3 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tup_N PF08581.5 EXF83276.1 - 0.02 15.0 0.7 0.02 15.0 0.5 4.6 3 1 1 4 4 3 0 Tup N-terminal Reo_sigmaC PF04582.7 EXF83276.1 - 0.028 13.6 19.6 1 8.4 1.5 3.1 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Myosin_tail_1 PF01576.14 EXF83276.1 - 0.14 9.8 64.5 0.3 8.7 44.6 1.5 1 1 0 1 1 1 0 Myosin tail IL31 PF15209.1 EXF83276.1 - 0.18 11.4 0.1 0.18 11.4 0.0 3.1 3 1 0 3 3 3 0 Interleukin 31 AAA_27 PF13514.1 EXF83276.1 - 0.21 9.2 47.6 0.31 8.6 33.0 1.2 1 0 0 1 1 1 0 AAA domain DUF3584 PF12128.3 EXF83276.1 - 0.22 8.7 52.5 0.81 6.9 36.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Seryl_tRNA_N PF02403.17 EXF83276.1 - 0.78 9.7 50.2 0.31 11.0 9.9 5.0 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Tropomyosin PF00261.15 EXF83276.1 - 0.78 8.7 67.2 0.38 9.8 13.8 3.2 1 1 0 2 2 2 0 Tropomyosin AAA_13 PF13166.1 EXF83276.1 - 1.3 7.4 44.4 1 7.7 5.5 2.7 1 1 1 2 2 2 0 AAA domain Atg14 PF10186.4 EXF83276.1 - 1.8 7.4 48.5 0.094 11.6 15.6 3.1 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Spc7 PF08317.6 EXF83276.1 - 2.8 6.4 51.6 0.67 8.5 17.7 2.9 1 1 1 2 2 2 0 Spc7 kinetochore protein IncA PF04156.9 EXF83276.1 - 2.9 7.4 62.7 0.68 9.4 6.3 3.4 1 1 2 3 3 3 0 IncA protein Baculo_PEP_C PF04513.7 EXF83276.1 - 3.3 7.5 21.4 0.4 10.4 1.3 3.8 1 1 3 4 4 4 0 Baculovirus polyhedron envelope protein, PEP, C terminus MscS_porin PF12795.2 EXF83276.1 - 4.4 6.5 52.4 2 7.6 10.4 2.9 2 1 0 2 2 2 0 Mechanosensitive ion channel porin domain NPV_P10 PF05531.7 EXF83276.1 - 4.6 7.5 19.4 0.31 11.3 0.8 4.6 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein Fib_alpha PF08702.5 EXF83276.1 - 4.6 7.3 33.2 0.13 12.3 7.0 3.7 1 1 3 4 4 4 0 Fibrinogen alpha/beta chain family Nup54 PF13874.1 EXF83276.1 - 8.8 5.9 38.4 0.25 11.0 1.1 3.7 2 1 0 3 3 3 0 Nucleoporin complex subunit 54 RRM_1 PF00076.17 EXF83277.1 - 9.7e-13 47.5 0.0 2.5e-12 46.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF83277.1 - 1.4e-10 41.0 0.0 2.8e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF83277.1 - 8.3e-08 31.9 0.2 1.8e-07 30.8 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CDC27 PF09507.5 EXF83277.1 - 0.66 9.1 48.7 0.85 8.7 21.4 2.3 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 SMN PF06003.7 EXF83278.1 - 1e-06 28.0 13.4 1.4e-05 24.3 0.5 2.9 1 1 2 3 3 3 2 Survival motor neuron protein (SMN) Cu_bind_like PF02298.12 EXF83279.1 - 0.19 11.5 0.2 0.96 9.2 0.1 1.9 1 1 0 1 1 1 0 Plastocyanin-like domain 4F5 PF04419.9 EXF83280.1 - 1e-10 42.1 15.4 1e-10 42.1 10.7 2.4 2 1 0 2 2 2 1 4F5 protein family PUF PF00806.14 EXF83281.1 - 1.2e-58 191.3 10.8 1.4e-07 30.5 0.0 8.5 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat TylF PF05711.6 EXF83281.1 - 0.071 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Macrocin-O-methyltransferase (TylF) ERM PF00769.14 EXF83282.1 - 0.00019 21.0 0.7 0.00025 20.6 0.5 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Lebercilin PF15619.1 EXF83282.1 - 0.12 11.7 9.4 0.18 11.1 6.5 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease MscS_TM PF12794.2 EXF83282.1 - 1.6 7.2 5.3 2.1 6.8 3.7 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 RNA_pol_Rpb2_6 PF00562.23 EXF83284.1 - 1.9e-116 388.9 0.0 3.2e-116 388.2 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EXF83284.1 - 2.2e-51 173.6 0.5 3.9e-51 172.8 0.1 1.6 2 0 0 2 2 2 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EXF83284.1 - 1.6e-30 105.9 0.1 3.4e-30 104.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EXF83284.1 - 4.9e-30 103.6 0.2 1.4e-29 102.1 0.2 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EXF83284.1 - 8.8e-21 73.4 0.1 2.4e-20 72.0 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EXF83284.1 - 3.2e-20 71.6 0.0 6.3e-20 70.6 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EXF83284.1 - 2.1e-11 43.6 0.7 8.7e-11 41.6 0.7 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 5 MFS_1 PF07690.11 EXF83287.1 - 1.8e-34 119.0 52.1 3.8e-29 101.5 10.6 2.7 2 1 0 3 3 3 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF83287.1 - 1.9e-08 32.9 11.7 1.9e-08 32.9 8.1 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Carn_acyltransf PF00755.15 EXF83290.1 - 5.6e-167 556.3 0.0 9.8e-151 502.7 0.0 2.0 2 0 0 2 2 2 2 Choline/Carnitine o-acyltransferase Podoplanin PF05808.6 EXF83291.1 - 0.0035 16.9 1.0 0.024 14.1 0.2 2.1 2 0 0 2 2 2 1 Podoplanin Yip1 PF04893.12 EXF83291.1 - 0.081 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Yip1 domain Syndecan PF01034.15 EXF83291.1 - 0.1 12.2 0.1 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Syndecan domain Rad51 PF08423.6 EXF83292.1 - 1.1e-21 76.8 0.0 1.6e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EXF83292.1 - 1.1e-09 37.9 0.0 2.1e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain RecA PF00154.16 EXF83292.1 - 1.3e-06 27.7 0.0 4.7e-05 22.5 0.0 2.0 2 0 0 2 2 2 1 recA bacterial DNA recombination protein KaiC PF06745.8 EXF83292.1 - 1.8e-06 27.2 0.0 3.6e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 KaiC PriCT_2 PF08707.6 EXF83292.1 - 0.02 14.7 0.0 0.056 13.3 0.0 1.7 1 0 0 1 1 1 0 Primase C terminal 2 (PriCT-2) AAA_22 PF13401.1 EXF83292.1 - 0.05 13.7 0.0 0.15 12.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EXF83292.1 - 0.16 12.2 0.1 0.29 11.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter Pox_A32 PF04665.7 EXF83292.1 - 0.22 10.8 0.1 0.44 9.8 0.1 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein Ras PF00071.17 EXF83293.1 - 5.5e-23 81.1 0.3 6.4e-23 80.9 0.2 1.1 1 0 0 1 1 1 1 Ras family WD40 PF00400.27 EXF83295.1 - 8.9e-17 60.2 9.9 0.0011 18.7 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat PQQ_3 PF13570.1 EXF83295.1 - 0.02 15.1 0.4 8.4 6.8 0.0 4.2 4 0 0 4 4 4 0 PQQ-like domain SGL PF08450.7 EXF83295.1 - 0.028 13.7 0.1 0.089 12.1 0.0 1.8 2 0 0 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Sigma70_r1_2 PF00140.15 EXF83295.1 - 0.038 13.6 0.9 0.092 12.4 0.7 1.7 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 WD40 PF00400.27 EXF83296.1 - 2.1e-25 87.5 3.2 2.8e-08 33.3 0.0 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat DUF3639 PF12341.3 EXF83296.1 - 6.6e-07 29.2 8.3 1.2e-06 28.3 3.1 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF3639) eIF2A PF08662.6 EXF83296.1 - 4.8e-06 26.4 0.0 5.3e-05 23.0 0.1 2.3 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EXF83296.1 - 0.00014 20.8 0.0 0.00073 18.4 0.0 1.8 1 1 1 2 2 2 1 Coatomer WD associated region Apc4_WD40 PF12894.2 EXF83296.1 - 0.00038 19.9 0.0 5.1 6.6 0.0 3.7 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Tachylectin PF14517.1 EXF83296.1 - 0.011 15.0 0.0 0.1 11.9 0.0 2.5 2 1 0 2 2 2 0 Tachylectin PQQ_3 PF13570.1 EXF83296.1 - 0.021 15.0 1.9 3 8.2 0.1 4.5 4 0 0 4 4 4 0 PQQ-like domain KTSC PF13619.1 EXF83296.1 - 0.069 12.7 0.0 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 KTSC domain BBS2_Mid PF14783.1 EXF83296.1 - 0.17 11.7 0.0 2.4 7.9 0.0 2.6 2 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DUF4613 PF15390.1 EXF83296.1 - 0.29 9.2 0.0 3.5 5.6 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4613) HSF_DNA-bind PF00447.12 EXF83297.1 - 3.3e-36 123.5 0.4 5.2e-36 122.9 0.3 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding HET PF06985.6 EXF83299.1 - 4.3e-33 114.4 0.6 7.4e-33 113.6 0.4 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Methyltransf_23 PF13489.1 EXF83301.1 - 1.2e-06 28.3 0.0 1.7e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF83301.1 - 0.00031 20.3 0.0 0.00083 18.9 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF83301.1 - 0.00098 19.6 0.0 0.0033 17.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF83301.1 - 0.0032 17.9 0.0 0.006 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain NICE-3 PF07406.6 EXF83303.1 - 0.0012 18.3 0.0 0.18 11.2 0.0 2.3 2 0 0 2 2 2 2 NICE-3 protein DUF4129 PF13559.1 EXF83303.1 - 0.007 16.3 0.2 0.02 14.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4129) DUF3827 PF12877.2 EXF83303.1 - 3.1 5.7 6.5 0.14 10.2 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) Ndc1_Nup PF09531.5 EXF83304.1 - 1.5e-135 453.0 0.5 1.7e-135 452.8 0.4 1.0 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Syntaxin_2 PF14523.1 EXF83305.1 - 9.5e-28 96.2 6.4 9.5e-28 96.2 4.4 2.5 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EXF83305.1 - 5.8e-16 57.9 5.8 2.7e-15 55.8 4.0 2.2 1 0 0 1 1 1 1 SNARE domain Synaptobrevin PF00957.16 EXF83305.1 - 0.017 14.7 2.7 0.018 14.6 0.5 2.2 2 0 0 2 2 2 0 Synaptobrevin MCPsignal PF00015.16 EXF83305.1 - 0.023 14.2 11.9 8 5.9 1.3 2.7 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Mnd1 PF03962.10 EXF83305.1 - 0.031 13.9 1.1 0.031 13.9 0.7 2.6 1 1 1 2 2 1 0 Mnd1 family DUF883 PF05957.8 EXF83305.1 - 0.031 14.6 13.6 0.43 11.0 0.0 3.4 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) Syntaxin-6_N PF09177.6 EXF83305.1 - 0.15 12.4 9.8 4.1 7.8 0.0 3.7 3 1 0 4 4 4 0 Syntaxin 6, N-terminal DUF1664 PF07889.7 EXF83305.1 - 0.18 11.6 11.2 1.1 9.0 1.9 3.3 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) Spectrin PF00435.16 EXF83305.1 - 0.66 10.2 12.2 4.9 7.4 1.5 3.2 2 1 1 3 3 3 0 Spectrin repeat Occludin_ELL PF07303.8 EXF83305.1 - 1.2 9.9 8.2 0.2 12.3 0.9 2.8 2 2 1 3 3 3 0 Occludin homology domain DUF3708 PF12501.3 EXF83305.1 - 5.5 6.7 10.7 3e+02 1.1 7.4 2.7 1 1 0 1 1 1 0 Phosphate ATP-binding cassette transporter DUF3450 PF11932.3 EXF83305.1 - 9.5 5.4 17.0 0.091 12.0 4.5 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) 60KD_IMP PF02096.15 EXF83306.1 - 2.5e-14 53.3 0.1 4e-14 52.7 0.1 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Glycos_transf_1 PF00534.15 EXF83307.1 - 8.3e-21 74.1 0.0 1.7e-20 73.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EXF83307.1 - 7.9e-10 39.0 0.0 7.6e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EXF83307.1 - 0.002 17.9 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 G_glu_transpept PF01019.16 EXF83308.1 - 1.6e-158 528.3 0.0 1.8e-158 528.1 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase tRNA_U5-meth_tr PF05958.6 EXF83309.1 - 1.8e-14 53.2 0.0 4.4e-13 48.6 0.0 2.3 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EXF83309.1 - 1.4e-07 31.2 0.0 2.5e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EXF83309.1 - 2.2e-07 30.5 0.0 3.9e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.2 EXF83309.1 - 0.00041 20.9 0.0 0.00099 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF83309.1 - 0.00042 20.3 0.0 0.00095 19.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EXF83309.1 - 0.0076 15.4 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TRM PF02005.11 EXF83309.1 - 0.027 13.4 0.1 0.078 11.8 0.0 1.7 2 0 0 2 2 2 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltrans_SAM PF10672.4 EXF83309.1 - 0.03 13.1 0.0 0.048 12.5 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase MTS PF05175.9 EXF83309.1 - 0.046 13.1 0.0 0.1 11.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain TRAM PF01938.15 EXF83309.1 - 0.046 13.5 0.1 0.11 12.2 0.1 1.6 1 0 0 1 1 1 0 TRAM domain Methyltransf_11 PF08241.7 EXF83309.1 - 0.08 13.4 0.0 0.22 12.0 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.10 EXF83309.1 - 0.1 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 UNC45-central PF11701.3 EXF83310.1 - 9.4e-50 168.3 0.0 3.4e-48 163.2 0.0 2.9 2 1 0 2 2 2 1 Myosin-binding striated muscle assembly central HEAT_2 PF13646.1 EXF83310.1 - 0.00063 19.9 24.9 0.046 13.9 2.9 6.9 3 3 4 7 7 7 3 HEAT repeats HEAT PF02985.17 EXF83310.1 - 0.046 13.8 6.4 6.6 7.0 0.0 5.3 5 0 0 5 5 5 0 HEAT repeat Tfb4 PF03850.9 EXF83311.1 - 6.9e-96 320.7 0.3 8.1e-96 320.5 0.2 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 zf-C2HC5 PF06221.8 EXF83311.1 - 0.017 14.8 4.9 0.029 14.1 3.4 1.3 1 0 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Asparaginase_2 PF01112.13 EXF83312.1 - 3.1e-35 121.4 2.5 8.6e-20 70.6 0.0 2.2 2 0 0 2 2 2 2 Asparaginase Actin PF00022.14 EXF83313.1 - 2e-90 303.0 0.0 4.4e-90 301.9 0.0 1.5 1 1 0 1 1 1 1 Actin ADH_N PF08240.7 EXF83314.1 - 1.9e-28 98.4 0.3 3.5e-28 97.5 0.2 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF83314.1 - 1.9e-27 95.3 0.1 3.3e-27 94.5 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF83314.1 - 0.0014 19.5 0.0 0.0025 18.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EXF83314.1 - 0.054 12.6 0.1 0.13 11.3 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain p450 PF00067.17 EXF83316.1 - 8.3e-66 222.3 0.0 1.1e-65 221.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 WD40 PF00400.27 EXF83317.1 - 5.3e-13 48.3 11.3 0.0014 18.4 0.2 7.2 7 0 0 7 7 7 3 WD domain, G-beta repeat HET PF06985.6 EXF83318.1 - 3.3e-28 98.5 0.0 4.9e-28 98.0 0.0 1.2 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Reovirus_cap PF00979.12 EXF83318.1 - 0.023 13.6 1.4 0.038 12.9 1.0 1.3 1 0 0 1 1 1 0 Reovirus outer capsid protein, Sigma 3 Alpha-L-AF_C PF06964.7 EXF83319.1 - 9.2e-28 97.1 0.0 1.7e-27 96.3 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus SnoaL PF07366.7 EXF83321.1 - 4.7e-16 58.5 0.0 7.6e-16 57.8 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EXF83321.1 - 0.00047 20.5 0.0 0.0014 18.9 0.0 1.9 1 1 0 1 1 1 1 SnoaL-like domain Fasciclin PF02469.17 EXF83323.1 - 1.2e-35 122.2 1.1 1.3e-23 83.4 0.2 2.1 2 0 0 2 2 2 2 Fasciclin domain Peptidase_S41 PF03572.13 EXF83324.1 - 9.6e-07 28.3 0.0 2.5e-06 27.0 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 DUF1772 PF08592.6 EXF83325.1 - 5.3e-20 71.5 0.9 7.8e-20 71.0 0.2 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF1772) DUF946 PF06101.6 EXF83326.1 - 1.3e-05 23.3 0.1 1.5e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) Ceramidase PF05875.7 EXF83327.1 - 1.4e-94 316.0 15.5 1.6e-94 315.9 10.8 1.0 1 0 0 1 1 1 1 Ceramidase DUF788 PF05620.6 EXF83327.1 - 0.046 13.5 0.5 0.046 13.5 0.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF788) GSP_synth PF03738.9 EXF83327.1 - 0.057 13.6 0.1 2.9 8.1 0.0 2.2 2 0 0 2 2 2 0 Glutathionylspermidine synthase preATP-grasp DnaJ PF00226.26 EXF83331.1 - 3.1e-19 68.4 2.0 4.9e-19 67.8 1.4 1.3 1 0 0 1 1 1 1 DnaJ domain DUF456 PF04306.8 EXF83331.1 - 0.0018 18.3 0.2 0.0029 17.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF456) Gly-zipper_OmpA PF13436.1 EXF83331.1 - 0.0018 17.9 4.4 0.058 13.0 3.9 2.4 2 1 0 2 2 2 1 Glycine-zipper containing OmpA-like membrane domain WHG PF13305.1 EXF83331.1 - 0.023 15.2 0.1 0.12 12.9 0.0 2.1 2 0 0 2 2 2 0 WHG domain DUF1183 PF06682.7 EXF83331.1 - 0.71 9.4 8.4 2.4 7.6 5.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) Bacteriocin_IIc PF10439.4 EXF83331.1 - 2.1 8.5 7.2 0.58 10.3 2.6 1.8 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_Omp PF13488.1 EXF83331.1 - 3.8 7.2 12.1 8.6 6.0 7.5 2.2 2 1 0 2 2 2 0 Glycine zipper Rick_17kDa_Anti PF05433.10 EXF83331.1 - 4.3 7.0 15.3 0.54 9.9 1.7 2.7 2 1 1 3 3 3 0 Glycine zipper 2TM domain Gly-zipper_YMGG PF13441.1 EXF83331.1 - 8.2 6.0 13.6 5.5 6.5 7.4 2.2 2 1 0 2 2 2 0 YMGG-like Gly-zipper Peptidase_M13_N PF05649.8 EXF83332.1 - 1.6e-61 208.5 0.0 2e-61 208.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M13 Peptidase_M13 PF01431.16 EXF83332.1 - 2.9e-53 180.1 0.1 5e-53 179.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M13 Flag1_repress PF03614.8 EXF83332.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Repressor of phase-1 flagellin Ank_5 PF13857.1 EXF83333.1 - 0.0002 21.4 0.0 0.00038 20.5 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EXF83333.1 - 0.045 13.5 0.0 0.078 12.8 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.1 EXF83333.1 - 0.13 12.8 0.0 0.21 12.1 0.0 1.3 1 0 0 1 1 1 0 Ankyrin repeats (many copies) UPF0560 PF10577.4 EXF83333.1 - 5 5.2 5.8 5.6 5.0 4.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Ank PF00023.25 EXF83335.1 - 3.1e-20 70.8 1.7 1.6e-05 24.4 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_2 PF12796.2 EXF83335.1 - 3.8e-18 65.5 0.0 6.1e-10 39.2 0.0 4.4 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EXF83335.1 - 1.2e-17 63.9 0.1 0.00016 22.0 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF83335.1 - 1e-12 46.9 0.5 0.0012 18.8 0.0 5.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 EXF83335.1 - 3.2e-10 39.9 0.2 9.2e-05 22.5 0.0 4.5 4 1 1 5 5 5 2 Ankyrin repeats (many copies) UPF0150 PF03681.10 EXF83335.1 - 0.05 13.2 0.1 2.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0150) LSM PF01423.17 EXF83339.1 - 6.2e-17 60.9 0.0 9.1e-17 60.3 0.0 1.2 1 0 0 1 1 1 1 LSM domain Ribosomal_L5_C PF00673.16 EXF83340.1 - 6.3e-23 80.3 0.0 8.7e-23 79.8 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EXF83340.1 - 6.5e-21 73.8 0.0 2.4e-20 72.0 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L5 ATP-synt_ab PF00006.20 EXF83341.1 - 8.4e-71 237.8 0.0 1.2e-70 237.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EXF83341.1 - 4.8e-26 91.4 0.3 2e-25 89.4 0.1 2.2 2 1 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EXF83341.1 - 1.4e-15 57.2 2.8 3.3e-15 56.0 2.0 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EXF83341.1 - 0.005 16.7 1.0 0.015 15.2 0.5 2.0 2 0 0 2 2 2 1 HAS barrel domain Arch_ATPase PF01637.13 EXF83341.1 - 0.12 12.0 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Carb_kinase PF01256.12 EXF83342.1 - 3.5e-54 183.6 0.1 5.3e-54 183.0 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Pico_P1A PF02226.11 EXF83342.1 - 0.039 13.6 0.0 0.18 11.5 0.0 1.9 2 0 0 2 2 2 0 Picornavirus coat protein (VP4) MPC PF03650.8 EXF83343.1 - 3.1e-35 120.6 0.0 3.7e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) DUF1798 PF08807.5 EXF83343.1 - 0.07 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Bacterial domain of unknown function (DUF1798) CPSase_L_D2 PF02786.12 EXF83344.1 - 3.1e-81 271.6 0.4 4.8e-81 271.0 0.2 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.13 EXF83344.1 - 3.7e-66 222.3 0.0 6.4e-66 221.5 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain CPSase_L_chain PF00289.17 EXF83344.1 - 5.6e-35 119.7 0.1 1.1e-34 118.7 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EXF83344.1 - 1e-31 109.0 0.0 3.9e-31 107.2 0.0 2.1 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain HMGL-like PF00682.14 EXF83344.1 - 8.2e-27 94.3 0.0 1.9e-26 93.2 0.0 1.6 1 0 0 1 1 1 1 HMGL-like ATP-grasp_4 PF13535.1 EXF83344.1 - 4.7e-20 72.1 0.1 1e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EXF83344.1 - 6.4e-19 67.3 3.4 1.2e-18 66.4 1.2 2.4 2 0 0 2 2 2 1 Biotin-requiring enzyme ATPgrasp_Ter PF15632.1 EXF83344.1 - 3.1e-15 55.7 0.0 3e-14 52.5 0.0 2.2 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 EXF83344.1 - 7.1e-11 41.5 2.3 5.5e-07 29.1 0.1 3.4 2 1 1 3 3 3 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EXF83344.1 - 1e-10 41.3 0.0 1.9e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EXF83344.1 - 1.6e-07 30.8 0.1 3.1e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain RimK PF08443.6 EXF83344.1 - 1.1e-06 28.3 0.0 3.6e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 RimK-like ATP-grasp domain HlyD_2 PF12700.2 EXF83344.1 - 6.7e-05 22.1 0.1 0.035 13.2 0.0 2.3 1 1 1 2 2 2 2 HlyD family secretion protein ATP-grasp_3 PF02655.9 EXF83344.1 - 7.6e-05 22.6 0.0 0.0002 21.2 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.1 EXF83344.1 - 0.00015 22.0 0.1 0.45 10.8 0.0 3.5 3 0 0 3 3 3 1 HlyD family secretion protein HlyD PF00529.15 EXF83344.1 - 0.0003 20.1 0.1 0.0092 15.3 0.0 2.4 2 0 0 2 2 2 1 HlyD family secretion protein DUF2118 PF09891.4 EXF83344.1 - 0.021 14.5 0.1 0.088 12.5 0.0 2.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) GARS_A PF01071.14 EXF83344.1 - 0.032 13.7 0.0 0.079 12.5 0.0 1.7 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain NQRA PF05896.6 EXF83344.1 - 0.056 12.6 0.2 0.098 11.8 0.1 1.3 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Rieske PF00355.21 EXF83344.1 - 0.12 12.0 0.0 0.29 10.7 0.0 1.6 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain RnfC_N PF13375.1 EXF83344.1 - 0.26 11.0 2.7 0.23 11.2 0.4 2.0 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain GCV_H PF01597.14 EXF83344.1 - 0.27 10.9 1.2 0.7 9.5 0.2 2.2 2 0 0 2 2 2 0 Glycine cleavage H-protein Proteasome PF00227.21 EXF83345.1 - 1.6e-45 154.7 0.0 1.4e-29 102.7 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EXF83345.1 - 7.3e-12 44.3 0.9 9.1e-12 44.0 0.0 1.6 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF4252 PF14060.1 EXF83346.1 - 0.0048 16.4 0.5 0.0085 15.6 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4252) CBP4 PF07960.6 EXF83346.1 - 0.13 11.8 8.0 0.12 11.9 3.1 2.5 2 0 0 2 2 2 0 CBP4 MOSC_N PF03476.11 EXF83346.1 - 0.26 11.0 1.2 0.53 9.9 0.8 1.5 1 0 0 1 1 1 0 MOSC N-terminal beta barrel domain DnaJ PF00226.26 EXF83348.1 - 1.3e-11 44.0 0.6 4.3e-11 42.3 0.4 1.9 1 1 0 1 1 1 1 DnaJ domain zf-RING_2 PF13639.1 EXF83350.1 - 6.5e-08 32.2 3.7 6.5e-08 32.2 2.6 2.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EXF83350.1 - 0.00089 18.8 1.6 0.00089 18.8 1.1 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EXF83350.1 - 0.0038 16.9 1.8 0.0083 15.8 1.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EXF83350.1 - 0.03 14.0 0.4 0.075 12.7 0.3 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Chisel PF15355.1 EXF83350.1 - 0.073 13.1 0.0 0.25 11.3 0.0 1.8 2 0 0 2 2 2 0 Stretch-responsive small skeletal muscle X protein, Chisel RINGv PF12906.2 EXF83350.1 - 0.092 12.8 4.7 0.27 11.3 3.2 1.9 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.1 EXF83350.1 - 0.7 9.9 8.5 0.034 14.1 1.4 2.3 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EXF83350.1 - 4 7.4 8.9 1 9.3 3.1 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain DNA_pol_phi PF04931.8 EXF83352.1 - 1.9e-54 184.7 36.4 7.2e-39 133.2 24.4 3.2 2 1 0 2 2 2 2 DNA polymerase phi DUF106 PF01956.11 EXF83352.1 - 5.2 6.5 4.5 6.3 6.2 0.0 2.8 3 0 0 3 3 3 0 Integral membrane protein DUF106 Rhodanese PF00581.15 EXF83353.1 - 5.7e-14 52.4 0.0 1.2e-13 51.4 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Glyco_tranf_2_3 PF13641.1 EXF83354.1 - 6.8e-16 58.7 0.0 9.1e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EXF83354.1 - 5.2e-07 29.1 0.0 1.2e-06 27.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EXF83354.1 - 0.00018 21.1 0.0 0.00065 19.4 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 HTH_20 PF12840.2 EXF83355.1 - 0.031 14.0 0.0 0.065 13.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain Dimerisation PF08100.6 EXF83355.1 - 0.033 14.0 0.0 0.058 13.2 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain Peptidase_A22B PF04258.8 EXF83356.1 - 8.3e-50 169.9 14.1 2.2e-48 165.2 9.8 2.6 1 1 0 1 1 1 1 Signal peptide peptidase UPF0233 PF06781.7 EXF83356.1 - 0.096 12.3 2.6 1.1 8.8 0.0 3.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) Pro_isomerase PF00160.16 EXF83357.1 - 2.7e-47 160.8 0.0 3.3e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Sgf11 PF08209.6 EXF83359.1 - 0.098 11.9 3.2 0.2 11.0 2.2 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) Acetyltransf_1 PF00583.19 EXF83360.1 - 1.3e-08 34.7 0.0 2.1e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF83360.1 - 0.0063 16.6 0.0 0.0093 16.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EXF83360.1 - 0.056 13.3 0.0 0.097 12.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EXF83360.1 - 0.091 12.8 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TFIIA PF03153.8 EXF83360.1 - 8.3 6.1 7.6 13 5.5 5.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Hexokinase_1 PF00349.16 EXF83361.1 - 3.4e-65 219.2 0.0 6.4e-65 218.3 0.0 1.5 1 0 0 1 1 1 1 Hexokinase Hexokinase_2 PF03727.11 EXF83361.1 - 1.6e-62 210.8 0.0 3.5e-62 209.7 0.0 1.5 1 1 0 1 1 1 1 Hexokinase adh_short PF00106.20 EXF83361.1 - 0.027 14.3 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase LacAB_rpiB PF02502.13 EXF83361.1 - 0.072 12.7 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 Ribose/Galactose Isomerase DUF791 PF05631.9 EXF83362.1 - 2e-69 233.9 9.0 3e-69 233.4 6.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 EXF83362.1 - 9.7e-18 63.9 26.7 9.7e-18 63.9 18.5 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3318 PF11780.3 EXF83362.1 - 0.037 13.5 0.7 0.28 10.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3318) Vpu PF00558.14 EXF83362.1 - 0.24 10.9 1.0 0.58 9.7 0.0 2.0 2 0 0 2 2 2 0 Vpu protein ATP-synt_G PF04718.10 EXF83364.1 - 2.3e-23 82.8 0.2 4.8e-23 81.7 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial ATP synthase g subunit HTH_Tnp_ISL3 PF13542.1 EXF83364.1 - 0.063 12.4 0.0 0.17 11.1 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 ADH_N PF08240.7 EXF83365.1 - 2.6e-27 94.7 2.0 5.6e-27 93.6 1.4 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF83365.1 - 1.6e-17 63.2 0.1 2.4e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase S1-like PF14444.1 EXF83365.1 - 0.0077 15.9 0.0 0.38 10.5 0.0 2.6 2 0 0 2 2 2 1 S1-like Isochorismatase PF00857.15 EXF83366.1 - 4e-26 91.9 0.0 9.4e-25 87.5 0.0 2.6 1 1 0 1 1 1 1 Isochorismatase family MDMPI_N PF11716.3 EXF83368.1 - 0.085 13.2 0.0 0.095 13.1 0.0 1.1 1 0 0 1 1 1 0 Mycothiol maleylpyruvate isomerase N-terminal domain Transp_cyt_pur PF02133.10 EXF83369.1 - 3.4e-42 144.5 37.5 4.2e-42 144.2 26.0 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin SET PF00856.23 EXF83370.1 - 7.3e-21 75.1 0.5 7.3e-21 75.1 0.3 2.6 2 1 0 2 2 2 1 SET domain Pil1 PF13805.1 EXF83371.1 - 3.3e-154 511.8 0.8 4e-154 511.5 0.5 1.1 1 0 0 1 1 1 1 Eisosome component PIL1 FAM92 PF06730.6 EXF83371.1 - 0.028 13.7 3.6 0.022 14.1 0.8 1.8 1 1 0 2 2 2 0 FAM92 protein LSM PF01423.17 EXF83372.1 - 3.8e-06 26.3 0.0 4.8e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EXF83372.1 - 0.12 12.2 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain XPG_N PF00752.12 EXF83373.1 - 1.6e-33 114.9 0.0 3.6e-33 113.8 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EXF83373.1 - 9.6e-27 92.8 0.0 2.5e-26 91.5 0.0 1.8 1 0 0 1 1 1 1 XPG I-region UIM PF02809.15 EXF83373.1 - 6e-05 22.2 3.6 0.0027 17.1 0.2 4.2 2 0 0 2 2 2 1 Ubiquitin interaction motif DUF2401 PF10287.4 EXF83374.1 - 2.9e-74 249.5 0.0 7e-74 248.2 0.0 1.6 2 0 0 2 2 2 1 Putative TOS1-like glycosyl hydrolase (DUF2401) DUF2403 PF10290.4 EXF83374.1 - 5.6e-22 77.6 0.3 2.2e-21 75.7 0.0 2.1 2 0 0 2 2 2 1 Glycine-rich protein domain (DUF2403) NmrA PF05368.8 EXF83375.1 - 2.3e-62 210.2 0.1 2.9e-62 209.9 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF83375.1 - 9.4e-16 58.3 0.1 1.5e-15 57.6 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EXF83375.1 - 1.1e-07 30.8 0.2 1.7e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EXF83375.1 - 0.012 15.6 0.2 0.021 14.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Saccharop_dh PF03435.13 EXF83375.1 - 0.026 13.5 0.9 0.052 12.5 0.2 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase Epimerase PF01370.16 EXF83375.1 - 0.054 12.9 0.2 0.1 11.9 0.2 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Peroxin-13_N PF04088.8 EXF83376.1 - 1.4e-56 190.8 0.0 2.2e-56 190.2 0.0 1.3 1 0 0 1 1 1 1 Peroxin 13, N-terminal region SH3_2 PF07653.12 EXF83376.1 - 3.6e-08 32.7 0.0 6.6e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EXF83376.1 - 1.5e-06 27.4 0.0 2.7e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EXF83376.1 - 5e-06 25.9 0.1 8.2e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_3 PF08239.6 EXF83376.1 - 0.014 15.5 0.1 0.063 13.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial SH3 domain Bap31 PF05529.7 EXF83377.1 - 4.2e-65 218.8 3.8 5.1e-65 218.5 2.7 1.1 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like DUF192 PF02643.10 EXF83377.1 - 0.0062 16.2 0.1 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized ACR, COG1430 Anoctamin PF04547.7 EXF83377.1 - 0.0063 15.2 0.2 0.0076 14.9 0.1 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel TMF_DNA_bd PF12329.3 EXF83377.1 - 0.009 15.7 3.9 0.016 15.0 2.7 1.4 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding DUF2956 PF11169.3 EXF83377.1 - 0.062 13.2 4.7 0.13 12.2 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Phage_GP20 PF06810.6 EXF83377.1 - 0.12 11.7 4.6 0.19 11.1 3.2 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 IncA PF04156.9 EXF83377.1 - 0.13 11.8 0.9 0.2 11.2 0.7 1.3 1 0 0 1 1 1 0 IncA protein DivIC PF04977.10 EXF83377.1 - 0.32 10.5 3.6 0.63 9.5 0.3 2.6 3 0 0 3 3 3 0 Septum formation initiator CBP PF12192.3 EXF83378.1 - 5.1e-07 29.5 4.3 1.3e-06 28.2 3.0 1.8 1 1 0 1 1 1 1 Fungal calcium binding protein Phospholip_A2_1 PF00068.14 EXF83379.1 - 0.21 11.8 5.7 0.26 11.5 4.0 1.1 1 0 0 1 1 1 0 Phospholipase A2 Dus PF01207.12 EXF83381.1 - 3e-36 124.8 0.0 2.6e-27 95.4 0.0 2.8 3 0 0 3 3 3 2 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EXF83381.1 - 0.64 9.7 9.7 1.2 8.8 0.0 2.8 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Metallophos PF00149.23 EXF83382.1 - 8.8e-39 132.9 0.2 1.1e-38 132.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SUR7 PF06687.7 EXF83383.1 - 4.8e-35 121.0 11.5 5.8e-35 120.7 8.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF4064 PF13273.1 EXF83383.1 - 0.042 13.9 1.1 0.042 13.9 0.8 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) IncA PF04156.9 EXF83383.1 - 9.7 5.7 0.0 9.7 5.7 0.0 3.0 3 0 0 3 3 3 0 IncA protein WD40 PF00400.27 EXF83384.1 - 3.1e-22 77.5 15.5 8.3e-09 35.0 0.1 9.5 9 0 0 9 9 9 7 WD domain, G-beta repeat 2OG-FeII_Oxy_2 PF13532.1 EXF83385.1 - 3.8e-21 75.8 0.1 1e-20 74.4 0.0 1.7 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Toxin_2 PF00451.14 EXF83385.1 - 0.26 11.3 5.8 0.88 9.7 4.0 1.9 1 0 0 1 1 1 0 Scorpion short toxin, BmKK2 AMP-binding PF00501.23 EXF83387.1 - 1.3e-72 244.5 0.0 1.6e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EXF83387.1 - 7.8e-14 52.3 1.5 3.6e-13 50.2 1.0 2.1 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Syndecan PF01034.15 EXF83389.1 - 3.8e-06 26.4 0.0 0.079 12.6 0.0 2.5 2 0 0 2 2 2 2 Syndecan domain EphA2_TM PF14575.1 EXF83389.1 - 0.00041 20.6 0.0 0.029 14.7 0.0 2.4 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain RCR PF12273.3 EXF83389.1 - 0.0012 19.4 1.3 0.11 13.0 0.0 2.5 2 1 0 2 2 2 1 Chitin synthesis regulation, resistance to Congo red DUF2029 PF09594.5 EXF83389.1 - 0.0015 18.0 1.2 0.73 9.2 0.3 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2029) MLANA PF14991.1 EXF83389.1 - 0.0017 18.3 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 2 Protein melan-A DUF4229 PF14012.1 EXF83389.1 - 0.0018 18.1 1.2 0.015 15.2 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4229) DUF1469 PF07332.6 EXF83389.1 - 0.0033 17.1 0.4 0.47 10.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1469) DUF4328 PF14219.1 EXF83389.1 - 0.0039 16.4 0.1 0.15 11.3 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4328) Herpes_gE PF02480.11 EXF83389.1 - 0.0058 14.9 0.0 0.096 10.9 0.1 2.1 2 0 0 2 2 2 1 Alphaherpesvirus glycoprotein E DUF204 PF02659.10 EXF83389.1 - 0.0099 15.9 3.8 1.8 8.7 0.3 2.5 2 0 0 2 2 2 2 Domain of unknown function DUF DUF202 PF02656.10 EXF83389.1 - 0.026 14.7 0.8 9.6 6.5 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF202) DUF998 PF06197.8 EXF83389.1 - 0.026 13.8 2.0 0.9 8.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF998) MFS_2 PF13347.1 EXF83389.1 - 0.027 12.8 0.1 0.34 9.2 0.0 2.0 2 0 0 2 2 2 0 MFS/sugar transport protein DUF3609 PF12259.3 EXF83389.1 - 0.03 12.9 0.0 3.1 6.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3609) DUF4381 PF14316.1 EXF83389.1 - 0.03 14.4 1.1 1.5 8.9 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF4131 PF13567.1 EXF83389.1 - 0.033 13.5 0.8 8.4 5.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) BatA PF07584.6 EXF83389.1 - 0.036 14.2 0.2 0.83 9.8 0.0 2.2 2 0 0 2 2 2 0 Aerotolerance regulator N-terminal PepSY_TM_2 PF13703.1 EXF83389.1 - 0.043 13.9 0.1 1 9.5 0.0 2.2 2 0 0 2 2 2 0 PepSY-associated TM helix DUF912 PF06024.7 EXF83389.1 - 0.066 13.2 0.0 0.18 11.8 0.0 1.7 2 0 0 2 2 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2207 PF09972.4 EXF83389.1 - 0.084 11.4 0.0 0.65 8.5 0.0 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Adeno_E3_CR2 PF02439.10 EXF83389.1 - 0.1 12.1 0.5 1.9 8.0 0.1 2.4 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 RseC_MucC PF04246.7 EXF83389.1 - 0.12 11.9 0.1 3.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Chordopox_A13L PF05961.6 EXF83389.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Chordopoxvirus A13L protein CcmH PF03918.9 EXF83389.1 - 0.13 11.2 1.2 2.2 7.2 0.0 2.8 3 0 0 3 3 3 0 Cytochrome C biogenesis protein SKG6 PF08693.5 EXF83389.1 - 1 8.7 15.0 0.97 8.8 5.1 2.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain MtrF PF09472.5 EXF83389.1 - 2.7 7.3 7.1 1.2 8.4 0.4 2.4 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) AAA_12 PF13087.1 EXF83390.1 - 5.8e-24 84.5 0.0 9.9e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EXF83390.1 - 2.5e-16 60.0 0.0 5.2e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EXF83390.1 - 0.00011 21.7 0.0 4.8 6.6 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.1 EXF83390.1 - 0.0027 17.3 0.0 1.6 8.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EXF83390.1 - 0.0056 16.4 0.0 0.057 13.1 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain UvrD_C_2 PF13538.1 EXF83390.1 - 0.0064 16.6 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_22 PF13401.1 EXF83390.1 - 0.026 14.6 0.0 1.4 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EXF83390.1 - 0.058 12.7 0.0 0.26 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain zf-C2H2 PF00096.21 EXF83391.1 - 2e-06 27.7 22.8 0.036 14.3 2.2 3.6 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF83391.1 - 6.6e-06 26.0 18.5 0.013 15.8 0.3 3.7 3 0 0 3 3 3 3 C2H2-type zinc finger Syndecan PF01034.15 EXF83391.1 - 0.16 11.6 0.6 0.33 10.6 0.4 1.4 1 0 0 1 1 1 0 Syndecan domain FANCL_C PF11793.3 EXF83391.1 - 0.23 11.4 2.7 0.46 10.4 1.8 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain zf-H2C2_2 PF13465.1 EXF83391.1 - 6.5 7.2 30.2 0.89 9.9 3.6 4.1 4 0 0 4 4 4 0 Zinc-finger double domain HSP70 PF00012.15 EXF83393.1 - 1.2e-79 267.9 6.5 1.7e-79 267.3 4.5 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EXF83393.1 - 5.2e-11 41.7 0.3 9.4e-11 40.8 0.2 1.4 1 0 0 1 1 1 1 MreB/Mbl protein PilM_2 PF11104.3 EXF83393.1 - 0.015 14.2 0.2 1.3 7.7 0.0 2.5 2 1 1 3 3 3 0 Type IV pilus assembly protein PilM; NT-C2 PF10358.4 EXF83394.1 - 2.4e-20 72.4 0.1 4.1e-20 71.7 0.1 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins Phostensin_N PF13916.1 EXF83394.1 - 0.29 11.1 3.2 0.7 9.9 2.2 1.6 1 0 0 1 1 1 0 PP1-regulatory protein, Phostensin N-terminal Glycoprotein_B PF00606.13 EXF83395.1 - 0.056 11.4 1.7 0.054 11.5 1.2 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B MDFI PF15316.1 EXF83395.1 - 0.12 12.3 2.6 0.075 13.0 0.9 1.3 1 1 0 1 1 1 0 MyoD family inhibitor zf-CHCC PF10276.4 EXF83395.1 - 0.22 11.3 1.3 0.39 10.6 0.2 1.8 2 0 0 2 2 2 0 Zinc-finger domain zf-BED PF02892.10 EXF83395.1 - 0.3 10.8 2.0 0.44 10.3 1.4 1.4 1 0 0 1 1 1 0 BED zinc finger ERCC4 PF02732.10 EXF83396.1 - 2.2e-24 85.8 0.0 7.1e-24 84.1 0.0 1.9 2 0 0 2 2 2 1 ERCC4 domain PBP_sp32 PF07222.7 EXF83397.1 - 0.069 12.3 0.8 0.075 12.1 0.6 1.0 1 0 0 1 1 1 0 Proacrosin binding protein sp32 WH1 PF00568.18 EXF83398.1 - 2.2e-25 88.5 0.1 3.2e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 EXF83398.1 - 0.0078 15.7 0.4 0.0078 15.7 0.2 1.9 2 0 0 2 2 2 1 WH2 motif eIF-1a PF01176.14 EXF83399.1 - 3e-27 93.8 0.2 4.2e-27 93.3 0.1 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Myb_DNA-bind_6 PF13921.1 EXF83399.1 - 0.074 13.1 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain vMSA PF00695.14 EXF83400.1 - 0.12 11.6 0.3 0.17 11.0 0.2 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus U1snRNP70_N PF12220.3 EXF83400.1 - 4.5 7.6 13.2 0.46 10.8 0.3 3.0 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal PTCB-BRCT PF12738.2 EXF83401.1 - 1.9e-11 43.6 0.0 4e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EXF83401.1 - 2.2e-10 40.5 0.0 4.3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain fn3 PF00041.16 EXF83401.1 - 0.00041 20.4 0.0 0.0011 19.0 0.0 1.7 1 0 0 1 1 1 1 Fibronectin type III domain DUF3006 PF11213.3 EXF83401.1 - 0.031 14.0 0.7 0.14 11.9 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3006) adh_short PF00106.20 EXF83402.1 - 3.9e-09 36.6 3.0 8.6e-07 29.0 0.3 3.0 2 1 0 2 2 2 2 short chain dehydrogenase KR PF08659.5 EXF83402.1 - 9.7e-05 22.1 0.2 0.00024 20.8 0.2 1.6 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF83402.1 - 0.0019 18.0 0.1 0.0031 17.3 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase TrkH PF02386.11 EXF83404.1 - 1.2e-73 247.7 21.9 5.4e-67 225.8 9.8 3.2 2 1 0 2 2 2 2 Cation transport protein Sugar_tr PF00083.19 EXF83405.1 - 5.6e-84 282.3 30.3 6.9e-84 281.9 21.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF83405.1 - 9.2e-22 77.2 29.2 7e-16 57.8 8.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF697 PF05128.7 EXF83405.1 - 0.068 12.6 0.3 0.17 11.3 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF697) GFO_IDH_MocA PF01408.17 EXF83406.1 - 2.6e-23 82.8 0.1 4.8e-23 81.9 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EXF83406.1 - 0.00026 20.7 0.1 0.0012 18.6 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain NAD_binding_2 PF03446.10 EXF83406.1 - 0.0018 18.1 0.1 0.0084 15.9 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_7 PF13241.1 EXF83406.1 - 0.023 14.9 0.1 0.046 13.9 0.1 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding Gp_dh_N PF00044.19 EXF83406.1 - 0.056 13.3 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain CoA_binding PF02629.14 EXF83406.1 - 0.15 12.6 0.3 0.44 11.0 0.1 1.9 2 0 0 2 2 2 0 CoA binding domain Fungal_trans PF04082.13 EXF83407.1 - 8.6e-13 47.7 0.0 1.6e-12 46.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain FMN_dh PF01070.13 EXF83408.1 - 1.2e-88 297.3 0.2 3.8e-48 164.1 0.0 2.1 1 1 1 2 2 2 2 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EXF83408.1 - 4.1e-22 77.7 0.0 7.7e-22 76.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EXF83408.1 - 1.9e-07 30.3 0.0 3.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EXF83408.1 - 0.00042 19.3 0.7 0.00042 19.3 0.5 1.7 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EXF83408.1 - 0.032 13.3 0.1 0.059 12.5 0.0 1.4 1 0 0 1 1 1 0 Nitronate monooxygenase DUF706 PF05153.10 EXF83409.1 - 2.7e-123 410.2 1.2 2.7e-123 410.2 0.8 1.3 2 0 0 2 2 2 1 Family of unknown function (DUF706) HD PF01966.17 EXF83409.1 - 0.07 13.1 0.3 0.94 9.5 0.0 2.6 2 1 1 3 3 3 0 HD domain Peroxidase_2 PF01328.12 EXF83411.1 - 4.4e-44 150.4 0.7 5.3e-44 150.1 0.5 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 F-box PF00646.28 EXF83413.1 - 2.3e-07 30.2 0.2 7.3e-07 28.6 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EXF83413.1 - 0.01 15.5 0.1 0.026 14.2 0.1 1.7 1 0 0 1 1 1 0 F-box-like Sec10 PF07393.6 EXF83414.1 - 6.1e-220 732.1 10.3 6.1e-220 732.1 7.2 1.3 2 0 0 2 2 2 1 Exocyst complex component Sec10 DUF1640 PF07798.6 EXF83414.1 - 0.06 13.3 0.2 0.06 13.3 0.2 2.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1640) Clr5 PF14420.1 EXF83416.1 - 1.3e-11 44.2 0.0 2.6e-11 43.2 0.0 1.5 1 0 0 1 1 1 1 Clr5 domain Peptidase_M43 PF05572.8 EXF83417.1 - 3.2e-15 56.0 0.7 4.9e-15 55.4 0.5 1.3 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.1 EXF83417.1 - 3.7e-06 27.0 0.1 5.2e-06 26.5 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EXF83417.1 - 5.1e-06 26.6 0.1 7.3e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EXF83417.1 - 3e-05 24.5 0.1 6.4e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EXF83417.1 - 0.00017 21.2 0.1 0.00022 20.8 0.1 1.2 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M10 PF00413.19 EXF83417.1 - 0.00021 21.0 0.0 0.0004 20.1 0.0 1.5 1 0 0 1 1 1 1 Matrixin Peptidase_M66 PF10462.4 EXF83417.1 - 0.023 13.5 1.4 0.041 12.7 1.0 1.4 1 0 0 1 1 1 0 Peptidase M66 DNA_binding_1 PF01035.15 EXF83417.1 - 0.07 12.8 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, DNA binding domain PepSY_2 PF13670.1 EXF83417.1 - 0.13 12.1 0.3 0.23 11.4 0.2 1.4 1 0 0 1 1 1 0 Peptidase propeptide and YPEB domain Ecm33 PF12454.3 EXF83417.1 - 0.24 11.2 1.5 0.82 9.5 0.1 2.4 2 1 1 3 3 3 0 GPI-anchored cell wall organization protein p450 PF00067.17 EXF83418.1 - 1e-52 179.2 0.0 1.4e-52 178.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EXF83420.1 - 7.7e-25 87.7 0.0 1.4e-24 86.9 0.0 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF83420.1 - 7.5e-13 48.5 0.0 1.1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF83420.1 - 5.8e-09 35.7 0.0 7.6e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EXF83420.1 - 9.5e-09 35.3 0.0 1.3e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EXF83420.1 - 0.00085 19.3 0.0 0.0037 17.2 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EXF83420.1 - 0.0031 16.2 0.0 0.0048 15.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EXF83420.1 - 0.11 11.4 0.0 0.3 9.9 0.0 1.7 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein TPR_4 PF07721.9 EXF83421.1 - 0.13 12.7 1.4 0.48 11.0 0.9 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat WD40 PF00400.27 EXF83423.1 - 1.1e-54 180.4 23.7 1e-08 34.7 0.0 8.8 9 0 0 9 9 9 7 WD domain, G-beta repeat F-box-like PF12937.2 EXF83423.1 - 9.4e-11 41.2 0.1 1.9e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EXF83423.1 - 1e-10 40.9 1.0 2.6e-10 39.6 0.2 2.1 2 1 0 2 2 2 1 F-box domain PQQ_2 PF13360.1 EXF83423.1 - 0.00036 20.0 0.5 1 8.7 0.0 3.2 3 0 0 3 3 3 2 PQQ-like domain UMPH-1 PF05822.7 EXF83423.1 - 0.16 11.2 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) PRANC PF09372.5 EXF83423.1 - 0.32 10.9 0.0 0.6 10.1 0.0 1.5 1 0 0 1 1 1 0 PRANC domain P53_tetramer PF07710.6 EXF83424.1 - 0.075 12.1 0.0 0.24 10.5 0.0 1.9 1 0 0 1 1 1 0 P53 tetramerisation motif FUSC PF04632.7 EXF83424.1 - 0.68 8.2 2.4 0.6 8.4 0.0 2.0 3 0 0 3 3 3 0 Fusaric acid resistance protein family GMC_oxred_N PF00732.14 EXF83425.1 - 7.7e-54 182.8 0.0 1.6e-53 181.7 0.0 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF83425.1 - 8e-37 126.7 0.0 1.4e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EXF83425.1 - 0.00023 20.2 0.0 0.0036 16.2 0.0 2.3 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF83425.1 - 0.0038 16.1 0.0 0.64 8.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Lycopene_cycl PF05834.7 EXF83425.1 - 0.027 13.3 0.0 0.042 12.7 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EXF83425.1 - 0.09 12.6 0.0 0.53 10.1 0.0 2.2 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase DLH PF01738.13 EXF83426.1 - 1.9e-25 89.4 0.1 2.2e-25 89.2 0.1 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EXF83426.1 - 1.1e-06 28.4 0.0 1.7e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF747 PF05346.6 EXF83427.1 - 2.4e-130 434.4 5.3 2.9e-130 434.1 3.6 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family DUF1761 PF08570.5 EXF83427.1 - 0.05 13.6 0.3 0.05 13.6 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1761) Macoilin PF09726.4 EXF83427.1 - 7.3 4.7 6.8 11 4.1 4.7 1.1 1 0 0 1 1 1 0 Transmembrane protein F-box PF00646.28 EXF83428.1 - 2.4e-08 33.3 0.3 2.4e-08 33.3 0.2 2.4 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EXF83428.1 - 9.8e-08 31.6 2.0 2.9e-07 30.0 0.1 2.4 2 0 0 2 2 2 1 F-box-like RPEL PF02755.10 EXF83428.1 - 0.0011 18.2 0.0 0.0065 15.7 0.0 2.2 2 0 0 2 2 2 1 RPEL repeat PRANC PF09372.5 EXF83428.1 - 0.026 14.4 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 PRANC domain F-box-like_2 PF13013.1 EXF83428.1 - 0.072 12.8 1.3 0.13 11.9 0.9 1.7 1 1 0 1 1 1 0 F-box-like domain LAMTOR PF15454.1 EXF83429.1 - 1.3e-19 70.2 0.1 1.8e-19 69.7 0.1 1.2 1 0 0 1 1 1 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Toxin_60 PF15607.1 EXF83429.1 - 0.077 13.0 0.0 0.26 11.3 0.0 1.8 2 0 0 2 2 2 0 Putative toxin 60 HAUS6_N PF14661.1 EXF83431.1 - 0.48 9.7 7.1 0.97 8.7 4.9 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus IncA PF04156.9 EXF83431.1 - 1.2 8.7 7.5 1.8 8.1 5.2 1.3 1 0 0 1 1 1 0 IncA protein Med7 PF05983.6 EXF83432.1 - 6.5e-48 162.5 0.0 7.8e-48 162.3 0.0 1.1 1 0 0 1 1 1 1 MED7 protein DUF2505 PF10698.4 EXF83432.1 - 0.028 13.9 0.0 0.09 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2505) SPOC PF07744.8 EXF83434.1 - 1.5e-19 70.6 0.0 3.2e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 SPOC domain TFIIS_M PF07500.9 EXF83434.1 - 3.9e-14 52.6 1.3 9.9e-14 51.3 0.9 1.7 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.24 EXF83434.1 - 6.1e-09 35.4 8.6 1.1e-08 34.5 6.0 1.5 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EXF83434.1 - 0.49 9.7 3.6 0.86 8.9 2.5 1.4 1 0 0 1 1 1 0 PHD-finger TraH_2 PF06871.6 EXF83434.1 - 7.4 5.9 7.5 0.67 9.3 0.1 2.4 1 1 1 2 2 2 0 TraH_2 Proteasome PF00227.21 EXF83435.1 - 3.1e-60 202.7 0.1 3.8e-60 202.4 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EXF83435.1 - 2.5e-14 52.2 0.2 6.9e-14 50.8 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature DUF2838 PF10998.3 EXF83436.1 - 3.8e-45 152.3 9.2 3.8e-45 152.3 6.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) Trichoplein PF13868.1 EXF83436.1 - 0.047 12.0 3.6 0.067 11.5 2.5 1.2 1 0 0 1 1 1 0 Tumour suppressor, Mitostatin IncA PF04156.9 EXF83436.1 - 0.19 11.2 0.4 0.42 10.1 0.3 1.5 1 0 0 1 1 1 0 IncA protein Tropomyosin_1 PF12718.2 EXF83436.1 - 2.8 7.7 5.5 0.28 11.0 0.3 1.8 3 0 0 3 3 3 0 Tropomyosin like SMC_N PF02463.14 EXF83437.1 - 3.6e-58 196.3 7.5 2.2e-57 193.8 5.2 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EXF83437.1 - 1.6e-24 86.1 0.1 1.3e-23 83.2 0.0 2.7 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain Reo_sigmaC PF04582.7 EXF83437.1 - 3.3e-08 33.1 14.9 0.0021 17.2 1.1 5.1 5 0 0 5 5 5 2 Reovirus sigma C capsid protein AAA_21 PF13304.1 EXF83437.1 - 4.9e-08 33.2 16.6 0.00023 21.2 0.1 3.8 3 2 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EXF83437.1 - 5e-08 32.3 0.0 9.8e-08 31.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain FliJ PF02050.11 EXF83437.1 - 0.0021 18.0 11.0 0.0021 18.0 7.6 8.1 4 1 4 8 8 7 2 Flagellar FliJ protein SbcCD_C PF13558.1 EXF83437.1 - 0.0041 17.0 0.0 0.027 14.3 0.0 2.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_13 PF13166.1 EXF83437.1 - 0.011 14.1 102.2 0.0098 14.4 8.3 7.0 4 2 2 7 7 7 0 AAA domain RIH_assoc PF08454.6 EXF83437.1 - 0.039 13.5 4.6 3.2 7.4 0.0 3.2 3 0 0 3 3 3 0 RyR and IP3R Homology associated AAA_22 PF13401.1 EXF83437.1 - 0.69 10.0 4.8 10 6.2 0.0 4.4 4 0 0 4 4 4 0 AAA domain Spc7 PF08317.6 EXF83437.1 - 1.6 7.2 102.4 0.014 14.0 10.7 6.8 3 2 4 7 7 6 0 Spc7 kinetochore protein DUF1664 PF07889.7 EXF83437.1 - 4 7.2 52.8 2.3 8.0 1.5 7.9 4 2 1 7 7 7 0 Protein of unknown function (DUF1664) TFIIE_alpha PF02002.12 EXF83438.1 - 1.4e-13 50.2 0.2 3.6e-13 48.9 0.1 1.7 1 0 0 1 1 1 1 TFIIE alpha subunit zf-FPG_IleRS PF06827.9 EXF83438.1 - 0.1 12.2 1.1 3.5 7.3 0.1 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS DNA_pol_lambd_f PF10391.4 EXF83439.1 - 1.2e-22 79.1 0.4 2.9e-22 77.9 0.3 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.1 EXF83439.1 - 9.9e-20 70.6 0.0 2e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EXF83439.1 - 7.7e-19 67.1 0.0 1.6e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb HHH_8 PF14716.1 EXF83439.1 - 1e-11 44.8 0.0 3e-11 43.3 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_5 PF14520.1 EXF83439.1 - 6.6e-05 23.0 0.0 0.083 13.0 0.0 2.4 2 0 0 2 2 2 2 Helix-hairpin-helix domain WSK PF03832.8 EXF83439.1 - 0.01 15.1 0.3 0.036 13.4 0.2 2.0 1 0 0 1 1 1 0 WSK motif NTP_transf_2 PF01909.18 EXF83439.1 - 0.02 15.1 0.1 0.078 13.3 0.0 2.0 2 0 0 2 2 2 0 Nucleotidyltransferase domain MAPEG PF01124.13 EXF83440.1 - 1.4e-22 79.7 0.2 1.6e-22 79.4 0.1 1.1 1 0 0 1 1 1 1 MAPEG family Peptidase_M14 PF00246.19 EXF83441.1 - 2.8e-62 210.8 0.0 3.7e-62 210.4 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Sec7 PF01369.15 EXF83442.1 - 6.4e-38 130.3 0.0 1.2e-37 129.4 0.0 1.4 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 EXF83442.1 - 1.1e-05 25.5 0.1 2.2e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 EXF83442.1 - 2.5e-05 24.4 0.1 5.3e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain SRP72 PF08492.7 EXF83443.1 - 3.5e-13 49.6 8.6 3.5e-13 49.6 6.0 2.6 2 0 0 2 2 2 1 SRP72 RNA-binding domain Apc3 PF12895.2 EXF83443.1 - 4.4e-07 29.9 11.7 3.6e-05 23.8 0.6 5.0 3 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EXF83443.1 - 5.4e-07 29.6 16.2 2.2 9.1 0.0 8.3 7 1 2 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.12 EXF83443.1 - 1.3e-06 27.8 13.9 0.025 14.4 0.1 6.4 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_12 PF13424.1 EXF83443.1 - 2.7e-05 24.0 16.1 0.13 12.2 0.1 7.0 6 2 1 7 7 7 1 Tetratricopeptide repeat SPO22 PF08631.5 EXF83443.1 - 0.00078 18.6 2.8 0.0033 16.5 0.2 2.9 2 2 1 3 3 3 1 Meiosis protein SPO22/ZIP4 like TPR_4 PF07721.9 EXF83443.1 - 0.0016 18.7 0.5 23 5.8 0.2 5.2 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EXF83443.1 - 0.0017 18.6 22.3 1.1 9.6 0.3 6.5 4 2 1 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EXF83443.1 - 0.0041 17.7 19.3 0.25 12.0 1.4 6.8 5 1 3 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 EXF83443.1 - 0.022 14.3 9.1 12 5.6 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 EXF83443.1 - 0.071 12.7 0.0 0.071 12.7 0.0 5.5 6 1 0 6 6 6 0 TPR repeat TPR_10 PF13374.1 EXF83443.1 - 0.082 12.8 8.5 24 5.0 0.0 5.6 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_3 PF07720.7 EXF83443.1 - 0.8 9.5 4.3 1.1 9.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EXF83443.1 - 0.96 10.0 10.5 89 3.8 0.1 6.5 7 0 0 7 7 6 0 Tetratricopeptide repeat HNF-1A_C PF04813.7 EXF83444.1 - 1.6 9.0 0.0 1.6 9.0 0.0 3.6 3 1 1 4 4 4 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus Aminotran_1_2 PF00155.16 EXF83446.1 - 7.4e-66 222.5 0.0 1.1e-65 222.0 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EXF83446.1 - 1.9e-05 24.0 0.0 2.7e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EXF83446.1 - 0.00057 19.0 0.0 0.013 14.6 0.0 2.3 3 0 0 3 3 3 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EXF83446.1 - 0.0006 18.2 0.0 0.0023 16.2 0.0 1.8 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EXF83446.1 - 0.0093 14.7 0.0 0.056 12.1 0.0 2.2 3 0 0 3 3 3 1 Aminotransferase class-V PP1_bind PF15276.1 EXF83448.1 - 0.011 15.7 2.0 0.011 15.7 1.4 3.5 2 2 1 3 3 3 0 Protein phosphatase 1 binding Pneumo_att_G PF05539.6 EXF83448.1 - 2.9 7.1 16.9 3.9 6.7 11.7 1.1 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G MFS_1 PF07690.11 EXF83449.1 - 2.7e-23 82.2 42.7 1.5e-22 79.8 28.7 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily FAD_binding_3 PF01494.14 EXF83450.1 - 4.6e-63 213.4 0.0 7e-63 212.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF83450.1 - 1.3e-06 27.5 1.2 0.0051 15.7 0.0 2.4 2 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF83450.1 - 7.6e-05 21.7 0.4 0.11 11.3 0.1 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_8 PF13450.1 EXF83450.1 - 0.0006 19.7 0.1 0.0015 18.5 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EXF83450.1 - 0.00067 18.8 0.0 0.0013 17.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EXF83450.1 - 0.00089 19.6 0.4 0.023 15.0 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF83450.1 - 0.0009 19.3 0.2 0.007 16.4 0.1 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF83450.1 - 0.0017 16.8 0.5 0.0026 16.3 0.0 1.4 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EXF83450.1 - 0.023 14.5 0.1 0.058 13.2 0.1 1.6 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DIT1_PvcA PF05141.7 EXF83451.1 - 7.5e-87 291.1 0.0 1.1e-86 290.6 0.0 1.2 1 0 0 1 1 1 1 Pyoverdine/dityrosine biosynthesis protein TauD PF02668.11 EXF83451.1 - 4.2e-24 85.6 0.0 7.3e-24 84.8 0.0 1.4 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family p450 PF00067.17 EXF83452.1 - 1.7e-33 115.8 0.0 2.8e-31 108.5 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 AA_permease_2 PF13520.1 EXF83453.1 - 2.3e-37 128.5 55.7 2.9e-37 128.2 38.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF83453.1 - 8.9e-18 63.8 44.4 1.4e-17 63.2 30.8 1.2 1 0 0 1 1 1 1 Amino acid permease VIT1 PF01988.14 EXF83453.1 - 0.051 13.0 0.1 0.051 13.0 0.1 3.2 3 2 0 3 3 3 0 VIT family FAD_binding_3 PF01494.14 EXF83454.1 - 6.8e-15 54.9 4.6 5.8e-13 48.6 3.2 2.9 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF83454.1 - 3.2e-07 29.6 0.1 0.00074 18.5 0.0 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase SE PF08491.5 EXF83454.1 - 1.2e-05 24.3 0.0 0.00056 18.8 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_9 PF13454.1 EXF83454.1 - 4.5e-05 23.2 0.5 0.00016 21.4 0.1 2.1 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EXF83454.1 - 0.00052 19.9 0.0 0.0014 18.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EXF83454.1 - 0.00053 20.1 0.0 0.0015 18.5 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF83454.1 - 0.0077 16.1 0.0 0.022 14.6 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF83454.1 - 0.011 14.6 0.1 0.022 13.6 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EXF83454.1 - 0.02 13.8 0.0 5.2 5.8 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.17 EXF83454.1 - 0.025 13.4 0.0 0.045 12.6 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.9 EXF83454.1 - 0.054 11.9 0.0 0.086 11.2 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Amino_oxidase PF01593.19 EXF83454.1 - 0.079 12.0 0.0 5.5 5.9 0.0 2.2 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Abhydrolase_6 PF12697.2 EXF83455.1 - 1.5e-28 100.1 0.0 1.8e-28 99.9 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF83455.1 - 3.3e-11 43.1 0.0 1.5e-10 40.9 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EXF83455.1 - 0.0036 17.5 0.0 0.0077 16.4 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.15 EXF83455.1 - 0.02 14.4 0.0 4.8 6.6 0.0 2.1 1 1 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.7 EXF83455.1 - 0.094 12.2 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase Fungal_trans PF04082.13 EXF83456.1 - 2.1e-11 43.2 0.1 3.5e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF83456.1 - 4.6e-07 29.6 10.5 7.9e-07 28.8 7.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CoA_transf_3 PF02515.12 EXF83457.1 - 5e-31 107.4 0.0 2.3e-30 105.2 0.0 1.8 2 0 0 2 2 2 1 CoA-transferase family III Dioxygenase_C PF00775.16 EXF83458.1 - 9.1e-52 174.9 0.0 1.2e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Dioxygenase Dioxygenase_N PF04444.9 EXF83458.1 - 6.5e-13 48.4 0.0 1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EXF83458.1 - 0.00038 20.4 0.0 0.0021 18.0 0.0 2.2 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain DUF4198 PF10670.4 EXF83458.1 - 0.065 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) OPT PF03169.10 EXF83459.1 - 1.1e-170 569.1 55.1 1.2e-170 568.9 38.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2427 PF10348.4 EXF83459.1 - 3 7.4 10.7 0.1 12.1 1.2 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF2427) HsbA PF12296.3 EXF83460.1 - 6.5e-08 32.4 2.3 1.1e-07 31.7 1.6 1.4 1 0 0 1 1 1 1 Hydrophobic surface binding protein A Thionin PF00321.12 EXF83463.1 - 0.029 14.5 0.4 0.029 14.5 0.2 1.7 2 0 0 2 2 2 0 Plant thionin LysM PF01476.15 EXF83464.1 - 3.5e-09 36.4 0.3 9.7e-09 34.9 0.1 1.8 2 0 0 2 2 2 1 LysM domain Na_H_Exchanger PF00999.16 EXF83465.1 - 1.3e-29 102.9 34.5 4.6e-24 84.6 15.7 3.1 3 0 0 3 3 3 3 Sodium/hydrogen exchanger family Trypan_PARP PF05887.6 EXF83465.1 - 0.00035 20.4 0.0 0.0016 18.2 0.0 2.0 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Shisa PF13908.1 EXF83465.1 - 0.2 11.8 1.5 0.63 10.1 1.1 1.8 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator MFS_1 PF07690.11 EXF83467.1 - 2.4e-49 167.9 36.5 2.4e-49 167.9 25.3 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF83467.1 - 6.2e-16 58.0 19.8 8.3e-16 57.5 13.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.8 EXF83467.1 - 0.0054 14.9 7.3 0.0074 14.4 5.1 1.2 1 0 0 1 1 1 1 Transmembrane secretion effector TOH_N PF12549.3 EXF83469.1 - 0.094 12.3 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Tyrosine hydroxylase N terminal UCR_TM PF02921.9 EXF83469.1 - 0.38 11.0 2.2 1.2 9.3 1.5 1.9 1 0 0 1 1 1 0 Ubiquinol cytochrome reductase transmembrane region DAO PF01266.19 EXF83470.1 - 6.1e-43 147.0 0.0 7.2e-43 146.8 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF83470.1 - 4.7e-06 26.5 0.0 1.5e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF83470.1 - 0.0012 18.7 0.0 0.17 11.7 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EXF83470.1 - 0.0064 15.1 0.0 0.65 8.5 0.0 2.1 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox_3 PF13738.1 EXF83470.1 - 0.017 15.1 0.0 0.064 13.3 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ThiF PF00899.16 EXF83470.1 - 0.021 14.6 0.0 0.059 13.2 0.0 1.7 2 0 0 2 2 2 0 ThiF family Shikimate_DH PF01488.15 EXF83470.1 - 0.045 13.8 0.0 0.085 12.9 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Thi4 PF01946.12 EXF83470.1 - 0.055 12.5 0.0 0.09 11.8 0.0 1.2 1 0 0 1 1 1 0 Thi4 family ApbA PF02558.11 EXF83470.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA OPT PF03169.10 EXF83471.1 - 1e-170 569.2 49.5 1.2e-170 569.0 34.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein Fungal_trans_2 PF11951.3 EXF83472.1 - 1.4e-71 241.1 2.7 1.8e-71 240.8 1.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF83472.1 - 1.3e-08 34.5 6.7 1.3e-08 34.5 4.6 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Adeno_E1A PF02703.9 EXF83472.1 - 0.0042 16.5 2.0 0.071 12.5 0.5 2.3 2 0 0 2 2 2 1 Early E1A protein NRDE PF05742.7 EXF83472.1 - 0.019 14.3 0.0 0.028 13.7 0.0 1.3 1 0 0 1 1 1 0 NRDE protein DUF2407_C PF13373.1 EXF83473.1 - 1.6e-31 109.1 0.0 2.2e-31 108.6 0.0 1.2 1 0 0 1 1 1 1 DUF2407 C-terminal domain DUF2407 PF10302.4 EXF83473.1 - 4.5e-27 94.0 0.0 1.2e-26 92.6 0.0 1.7 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain ubiquitin PF00240.18 EXF83473.1 - 0.0041 16.4 0.0 0.01 15.2 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD_2 PF13881.1 EXF83473.1 - 0.05 13.4 0.0 0.13 12.1 0.0 1.7 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like TT_ORF2 PF02957.10 EXF83473.1 - 8.4 7.1 7.3 5.3 7.7 0.1 2.8 2 1 1 3 3 3 0 TT viral ORF2 rRNA_proc-arch PF13234.1 EXF83474.1 - 6.9e-90 300.8 0.0 1.3e-89 299.9 0.0 1.5 1 0 0 1 1 1 1 rRNA-processing arch domain DSHCT PF08148.7 EXF83474.1 - 9.2e-58 194.4 1.3 9.2e-58 194.4 0.9 1.7 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.24 EXF83474.1 - 1.9e-22 79.5 0.0 7.4e-22 77.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF83474.1 - 2.1e-08 33.8 0.0 4.6e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EXF83474.1 - 0.006 16.4 0.0 0.078 12.8 0.0 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit T2SE PF00437.15 EXF83474.1 - 0.03 13.2 0.0 0.06 12.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein COX7C PF02935.11 EXF83475.1 - 4.5e-13 48.7 2.8 5.2e-13 48.5 1.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIIc PPR_2 PF13041.1 EXF83476.1 - 2.2e-20 72.3 1.3 1.8e-07 30.9 0.0 5.4 4 1 1 5 5 5 5 PPR repeat family PPR_3 PF13812.1 EXF83476.1 - 2.6e-20 70.9 0.9 4.2e-05 23.5 0.0 6.7 6 0 0 6 6 6 4 Pentatricopeptide repeat domain PPR PF01535.15 EXF83476.1 - 1.5e-12 46.5 8.7 9.3e-06 25.2 0.1 5.7 6 1 0 6 6 6 2 PPR repeat PPR_1 PF12854.2 EXF83476.1 - 1.1e-06 28.0 6.0 0.0043 16.5 0.0 4.4 4 1 0 4 4 4 3 PPR repeat MRP-S25 PF13741.1 EXF83477.1 - 7.3e-70 235.0 8.9 9.4e-63 211.7 4.1 2.2 1 1 1 2 2 2 2 Mitochondrial ribosomal protein S25 Alg14 PF08660.6 EXF83478.1 - 1e-41 142.7 0.0 1.4e-41 142.3 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Ima1_N PF09779.4 EXF83479.1 - 2.3e-26 92.8 0.3 4.2e-26 91.9 0.2 1.4 1 0 0 1 1 1 1 Ima1 N-terminal domain Y_phosphatase2 PF03162.8 EXF83480.1 - 1.6e-45 154.4 0.0 2.8e-45 153.6 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EXF83480.1 - 5.4e-11 43.0 0.0 2.8e-09 37.4 0.0 2.3 1 1 1 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EXF83480.1 - 0.0036 16.6 0.1 0.0054 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EXF83480.1 - 0.0043 16.6 0.0 0.0079 15.7 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DUF1863 PF08937.6 EXF83480.1 - 0.13 12.3 0.1 0.21 11.6 0.1 1.3 1 0 0 1 1 1 0 MTH538 TIR-like domain (DUF1863) DUF2416 PF10315.4 EXF83481.1 - 0.0096 16.1 0.4 0.24 11.6 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF2416) Fumerase PF05681.9 EXF83481.1 - 0.17 10.9 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Fumarate hydratase (Fumerase) DUF1977 PF09320.6 EXF83482.1 - 5.6e-23 81.2 0.0 1.1e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1977) DnaJ PF00226.26 EXF83482.1 - 9.1e-22 76.5 0.1 1.6e-21 75.8 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Steroid_dh PF02544.11 EXF83483.1 - 8.2e-17 61.3 1.8 1.4e-14 54.1 1.2 2.2 1 1 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.7 EXF83483.1 - 0.00029 20.2 0.2 0.00053 19.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF3953 PF13129.1 EXF83483.1 - 1.4 8.6 5.5 0.17 11.5 0.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3953) KilA-N PF04383.8 EXF83484.1 - 0.0007 19.1 0.0 0.0074 15.8 0.0 2.2 1 1 0 1 1 1 1 KilA-N domain Med1 PF10744.4 EXF83485.1 - 4.8e-40 137.5 0.0 7.6e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Mediator of RNA polymerase II transcription subunit 1 GATase_2 PF00310.16 EXF83486.1 - 7.8e-22 77.4 0.2 2.2e-16 59.5 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_6 PF13522.1 EXF83486.1 - 3.8e-15 56.0 0.0 8.4e-15 54.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EXF83486.1 - 8.8e-15 54.5 0.0 3.2e-14 52.7 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EXF83486.1 - 6e-14 51.8 0.2 1.5e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.1 EXF83486.1 - 1.8e-05 23.5 0.0 2.8e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II ADH_zinc_N PF00107.21 EXF83486.1 - 0.058 12.9 0.1 2.5 7.6 0.0 3.0 3 0 0 3 3 3 0 Zinc-binding dehydrogenase Stc1 PF12898.2 EXF83487.1 - 9e-16 57.7 1.5 1.7e-15 56.8 1.1 1.5 1 0 0 1 1 1 1 Stc1 domain RAP1 PF07218.6 EXF83487.1 - 0.062 11.3 1.9 0.085 10.9 1.3 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) BCDHK_Adom3 PF10436.4 EXF83488.1 - 3.1e-69 231.6 0.0 4.7e-69 231.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.21 EXF83488.1 - 2.3e-17 62.7 0.0 4.3e-17 61.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EXF83488.1 - 0.0065 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Sorb PF02208.11 EXF83488.1 - 0.091 12.1 0.0 0.67 9.3 0.0 2.2 2 0 0 2 2 2 0 Sorbin homologous domain Golgin_A5 PF09787.4 EXF83489.1 - 0.00047 18.8 0.3 0.00094 17.8 0.2 1.4 1 0 0 1 1 1 1 Golgin subfamily A member 5 Tropomyosin_1 PF12718.2 EXF83489.1 - 0.017 14.9 2.9 0.017 14.9 2.0 1.8 2 0 0 2 2 2 0 Tropomyosin like GP41 PF00517.12 EXF83489.1 - 0.19 11.3 0.6 0.35 10.3 0.4 1.4 1 0 0 1 1 1 0 Retroviral envelope protein Alpha-amylase PF00128.19 EXF83490.1 - 4.2e-56 190.6 0.0 6.3e-56 190.0 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EXF83490.1 - 1.3e-13 50.8 0.0 3.3e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1966) Sugar_tr PF00083.19 EXF83491.1 - 1e-92 311.0 24.6 1.4e-92 310.6 17.0 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF83491.1 - 4.3e-21 75.0 18.3 4.3e-21 75.0 12.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF726 PF05277.7 EXF83493.1 - 1.1e-122 409.3 4.3 1.3e-122 408.9 3.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF726) Glu-tRNAGln PF02686.10 EXF83494.1 - 1e-05 25.1 0.1 3.4e-05 23.5 0.1 1.9 1 1 0 1 1 1 1 Glu-tRNAGln amidotransferase C subunit SNAP PF14938.1 EXF83495.1 - 4.1e-114 380.5 14.7 4.6e-114 380.3 10.2 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_2 PF07719.12 EXF83495.1 - 4.3e-07 29.3 9.7 0.71 9.9 0.0 5.9 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EXF83495.1 - 7.6e-07 28.9 12.0 0.0081 16.0 0.8 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EXF83495.1 - 1.1e-05 25.9 14.0 0.014 16.0 0.0 4.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EXF83495.1 - 0.001 18.6 15.1 0.012 15.2 0.7 4.0 1 1 3 4 4 4 2 TPR repeat TPR_6 PF13174.1 EXF83495.1 - 0.0012 19.1 11.5 15 6.2 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EXF83495.1 - 0.0024 17.5 9.4 2 8.4 0.2 5.4 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.1 EXF83495.1 - 0.0035 17.0 8.0 1.9 8.4 0.2 5.0 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EXF83495.1 - 0.017 14.7 13.0 0.45 10.2 0.0 5.2 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 EXF83495.1 - 0.11 13.1 15.3 24 5.9 0.2 5.5 2 1 4 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.1 EXF83495.1 - 0.18 11.6 4.4 1 9.2 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 EXF83495.1 - 0.41 10.0 3.2 1.3 8.4 2.2 1.8 1 1 0 1 1 1 0 Foie gras liver health family 1 TPR_3 PF07720.7 EXF83495.1 - 1.3 8.9 6.9 2.9 7.7 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EXF83495.1 - 3.7 7.5 11.2 3.5 7.5 0.4 4.4 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain DENN PF02141.16 EXF83496.1 - 7.7e-58 195.2 0.1 1.3e-57 194.5 0.0 1.3 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EXF83496.1 - 5.1e-17 61.6 0.0 1e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 EXF83496.1 - 5.2e-17 61.6 0.2 9.9e-17 60.7 0.1 1.5 1 0 0 1 1 1 1 dDENN domain C1_1 PF00130.17 EXF83496.1 - 0.008 15.8 8.9 0.018 14.7 6.2 1.6 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EXF83496.1 - 0.087 12.5 6.1 0.15 11.7 4.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.24 EXF83496.1 - 0.28 10.9 6.6 0.71 9.6 4.6 1.8 1 0 0 1 1 1 0 PHD-finger C1_2 PF03107.11 EXF83496.1 - 0.36 10.9 5.8 0.69 10.0 4.0 1.5 1 0 0 1 1 1 0 C1 domain C1_3 PF07649.7 EXF83496.1 - 0.55 10.3 5.3 1.1 9.3 3.7 1.6 1 0 0 1 1 1 0 C1-like domain zf-HIT PF04438.11 EXF83496.1 - 3.5 7.3 5.1 6.8 6.4 3.5 1.4 1 0 0 1 1 1 0 HIT zinc finger DUF974 PF06159.8 EXF83497.1 - 6.7e-82 274.6 0.0 8.2e-82 274.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF974) KH_1 PF00013.24 EXF83498.1 - 1.9e-11 43.4 0.0 5.4e-08 32.3 0.0 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EXF83498.1 - 6.8e-07 28.7 0.2 0.00025 20.5 0.0 3.1 3 0 0 3 3 3 2 KH domain ALS_ss_C PF10369.4 EXF83499.1 - 1.6e-19 69.4 0.0 3.6e-18 65.0 0.0 2.5 2 0 0 2 2 2 1 Small subunit of acetolactate synthase ACT PF01842.20 EXF83499.1 - 7.5e-13 47.6 0.1 1.4e-12 46.7 0.1 1.5 1 0 0 1 1 1 1 ACT domain ACT_5 PF13710.1 EXF83499.1 - 4.6e-10 39.1 0.0 8.4e-10 38.3 0.0 1.5 1 0 0 1 1 1 1 ACT domain OTCace_N PF02729.16 EXF83500.1 - 5.7e-42 142.7 0.1 8e-42 142.2 0.0 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.19 EXF83500.1 - 6.9e-39 133.2 0.0 1.9e-38 131.8 0.0 1.7 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Gp_dh_N PF00044.19 EXF83500.1 - 0.0033 17.4 0.0 0.34 10.8 0.0 2.3 2 0 0 2 2 2 2 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Adeno_PVIII PF01310.13 EXF83500.1 - 0.049 13.4 0.1 0.072 12.8 0.0 1.2 1 0 0 1 1 1 0 Adenovirus hexon associated protein, protein VIII DUF3712 PF12505.3 EXF83501.1 - 3e-07 30.5 0.0 6e-05 23.0 0.0 2.9 2 0 0 2 2 2 2 Protein of unknown function (DUF3712) SART-1 PF03343.8 EXF83504.1 - 5.6e-157 523.7 63.1 6.5e-157 523.5 43.8 1.0 1 0 0 1 1 1 1 SART-1 family Glyco_hydro_15 PF00723.16 EXF83505.1 - 1.8e-104 349.8 0.0 2.1e-104 349.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 15 CBM_20 PF00686.14 EXF83505.1 - 7.3e-35 118.4 0.6 1.7e-34 117.3 0.4 1.6 1 0 0 1 1 1 1 Starch binding domain AAA_17 PF13207.1 EXF83506.1 - 9.8e-06 26.3 0.0 5.1e-05 24.0 0.0 2.3 1 1 0 1 1 1 1 AAA domain CPT PF07931.7 EXF83506.1 - 4.3e-05 23.1 0.0 7e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.1 EXF83506.1 - 0.0023 18.2 0.0 0.0054 17.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain PRK PF00485.13 EXF83506.1 - 0.035 13.6 0.0 0.092 12.2 0.0 1.7 2 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_28 PF13521.1 EXF83506.1 - 0.044 13.7 0.0 0.076 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain TAA-Trp-ring PF15401.1 EXF83506.1 - 0.09 13.0 0.1 0.29 11.3 0.1 1.9 2 0 0 2 2 2 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin Zeta_toxin PF06414.7 EXF83506.1 - 0.11 11.5 0.0 0.76 8.8 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin CoaE PF01121.15 EXF83506.1 - 0.11 11.8 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_33 PF13671.1 EXF83506.1 - 0.13 12.1 0.0 0.31 10.9 0.0 1.7 2 1 0 2 2 2 0 AAA domain PTH2 PF01981.11 EXF83507.1 - 9.6e-45 151.0 0.2 1.3e-44 150.6 0.2 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 BING4CT PF08149.6 EXF83508.1 - 3e-37 125.9 0.0 1.3e-34 117.5 0.0 3.5 3 0 0 3 3 3 1 BING4CT (NUC141) domain WD40 PF00400.27 EXF83508.1 - 4.6e-09 35.8 0.0 4.6e-05 23.1 0.0 4.2 5 0 0 5 5 5 2 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EXF83508.1 - 4.2e-05 22.5 0.1 0.00011 21.1 0.0 1.6 2 0 0 2 2 2 1 Coatomer WD associated region MFS_1 PF07690.11 EXF83509.1 - 7.6e-18 64.3 35.5 7.6e-18 64.3 24.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF83509.1 - 0.0012 17.4 29.4 0.25 9.8 20.4 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter DUF2839 PF10999.3 EXF83509.1 - 0.53 10.3 4.6 8.6 6.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) CAP59_mtransfer PF11735.3 EXF83511.1 - 1.5e-62 211.0 0.0 2e-62 210.6 0.0 1.1 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 ABC_tran PF00005.22 EXF83512.1 - 3.1e-46 157.0 0.4 1.9e-22 80.0 0.0 3.6 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EXF83512.1 - 3.3e-14 53.5 0.5 0.0006 19.8 0.0 4.3 4 0 0 4 4 4 4 AAA domain AAA_29 PF13555.1 EXF83512.1 - 6.4e-09 35.2 0.1 9.5e-05 21.8 0.0 3.0 3 0 0 3 3 3 2 P-loop containing region of AAA domain SET PF00856.23 EXF83512.1 - 2.9e-08 34.1 0.6 7.6e-06 26.3 0.0 3.2 3 1 0 3 3 3 1 SET domain SMC_N PF02463.14 EXF83512.1 - 1e-07 31.4 3.2 0.077 12.2 0.0 4.4 4 1 0 5 5 5 2 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EXF83512.1 - 1.8e-07 32.0 0.3 0.0085 16.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.18 EXF83512.1 - 2.1e-06 27.6 0.1 0.046 13.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase ABC_tran_2 PF12848.2 EXF83512.1 - 3.1e-06 26.9 1.5 3.1e-06 26.9 1.0 2.1 2 0 0 2 2 1 1 ABC transporter AAA_22 PF13401.1 EXF83512.1 - 1.2e-05 25.4 1.6 0.1 12.7 0.1 3.5 2 2 1 3 3 3 2 AAA domain Miro PF08477.8 EXF83512.1 - 1.8e-05 25.2 0.0 0.087 13.3 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein DUF258 PF03193.11 EXF83512.1 - 3.1e-05 23.2 0.1 0.27 10.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 NACHT PF05729.7 EXF83512.1 - 4.8e-05 23.0 0.0 0.029 14.0 0.0 3.0 3 0 0 3 3 2 1 NACHT domain AAA_16 PF13191.1 EXF83512.1 - 6.8e-05 22.9 4.9 0.17 11.8 1.4 3.2 2 2 0 2 2 2 2 AAA ATPase domain AAA_28 PF13521.1 EXF83512.1 - 7.4e-05 22.7 0.8 0.017 15.0 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_33 PF13671.1 EXF83512.1 - 9e-05 22.3 0.1 0.31 10.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EXF83512.1 - 0.00015 21.5 0.1 0.085 12.5 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EXF83512.1 - 0.0003 20.3 0.7 0.91 8.9 0.0 2.9 3 0 0 3 3 2 2 AAA-like domain Dynamin_N PF00350.18 EXF83512.1 - 0.00035 20.4 0.9 0.7 9.6 0.0 2.9 2 1 0 2 2 2 2 Dynamin family AAA_18 PF13238.1 EXF83512.1 - 0.00043 20.5 2.7 0.2 11.9 0.0 3.1 3 0 0 3 3 2 1 AAA domain ArgK PF03308.11 EXF83512.1 - 0.00066 18.5 0.5 0.13 10.9 0.0 2.4 2 0 0 2 2 2 1 ArgK protein AAA_30 PF13604.1 EXF83512.1 - 0.0018 17.8 0.8 1.3 8.5 0.0 3.2 3 0 0 3 3 3 1 AAA domain DUF87 PF01935.12 EXF83512.1 - 0.0019 18.0 10.0 0.064 13.0 0.1 3.1 4 0 0 4 4 3 2 Domain of unknown function DUF87 AAA PF00004.24 EXF83512.1 - 0.0044 17.2 0.0 0.65 10.1 0.0 2.8 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.1 EXF83512.1 - 0.0051 17.1 13.3 0.12 12.7 2.2 3.6 3 1 0 3 3 3 2 AAA domain AAA_14 PF13173.1 EXF83512.1 - 0.0059 16.5 0.1 5 7.0 0.0 3.5 4 0 0 4 4 4 0 AAA domain Thymidylate_kin PF02223.12 EXF83512.1 - 0.0078 15.6 0.1 1.2 8.5 0.0 2.5 2 0 0 2 2 2 1 Thymidylate kinase AAA_25 PF13481.1 EXF83512.1 - 0.014 14.8 1.2 0.31 10.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain Arf PF00025.16 EXF83512.1 - 0.017 14.3 0.6 0.17 11.1 0.1 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family DUF815 PF05673.8 EXF83512.1 - 0.019 13.8 0.1 4.2 6.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NTPase_1 PF03266.10 EXF83512.1 - 0.02 14.6 0.1 4.7 6.8 0.0 2.8 3 0 0 3 3 2 0 NTPase RNA_helicase PF00910.17 EXF83512.1 - 0.022 14.9 0.1 3.3 7.9 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_15 PF13175.1 EXF83512.1 - 0.023 13.7 2.9 0.082 11.9 0.0 2.9 5 0 0 5 5 3 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EXF83512.1 - 0.024 14.1 0.7 0.26 10.7 0.1 2.6 2 1 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.14 EXF83512.1 - 0.029 13.8 0.6 3.7 6.9 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 EXF83512.1 - 0.03 14.0 0.0 0.76 9.4 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase ATP-synt_ab PF00006.20 EXF83512.1 - 0.055 12.9 0.0 8.5 5.8 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_5 PF07728.9 EXF83512.1 - 0.068 12.8 0.5 1.5 8.5 0.0 3.1 3 1 0 3 3 2 0 AAA domain (dynein-related subfamily) UPF0079 PF02367.12 EXF83512.1 - 0.11 12.1 0.2 4.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_13 PF13166.1 EXF83512.1 - 2.7 6.3 13.3 2.5 6.4 2.1 3.4 3 1 0 3 3 3 0 AAA domain NB-ARC PF00931.17 EXF83512.1 - 3.4 6.4 7.5 2.5 6.8 0.0 3.3 4 0 0 4 4 4 0 NB-ARC domain Gti1_Pac2 PF09729.4 EXF83513.1 - 5.6e-59 198.7 0.0 8.1e-59 198.2 0.0 1.2 1 0 0 1 1 1 1 Gti1/Pac2 family CDP-OH_P_transf PF01066.16 EXF83514.1 - 1.3e-17 63.9 3.9 1.3e-17 63.9 2.7 1.6 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase GIDA PF01134.17 EXF83515.1 - 1.8e-158 527.5 0.0 2.3e-158 527.1 0.0 1.1 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EXF83515.1 - 3.1e-16 59.2 0.3 8.3e-15 54.6 0.0 2.6 1 1 1 2 2 2 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 EXF83515.1 - 3.9e-06 26.9 0.2 1.1e-05 25.4 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EXF83515.1 - 4.7e-06 25.9 0.5 8.5e-06 25.1 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF83515.1 - 0.0047 15.8 2.5 0.0047 15.8 1.7 1.9 3 0 0 3 3 3 1 FAD binding domain DAO PF01266.19 EXF83515.1 - 0.0072 15.2 3.0 0.45 9.3 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EXF83515.1 - 0.016 14.8 1.1 0.036 13.6 0.8 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 EXF83515.1 - 0.93 7.8 5.5 1.6 7.1 0.5 2.5 3 0 0 3 3 3 0 HI0933-like protein Sec1 PF00995.18 EXF83516.1 - 2.7e-152 508.3 0.0 3.2e-152 508.0 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DUF2404 PF10296.4 EXF83517.1 - 6.9e-07 29.3 0.0 1.2e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Putative integral membrane protein conserved region (DUF2404) Tn7_Tnp_TnsA_C PF08721.6 EXF83517.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 TnsA endonuclease C terminal Abi PF02517.11 EXF83518.1 - 5.9e-12 45.5 10.4 5.9e-12 45.5 7.2 2.7 2 1 0 2 2 2 1 CAAX protease self-immunity Ribosomal_60s PF00428.14 EXF83519.1 - 0.0077 16.6 2.7 0.013 15.9 1.9 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein MBOAT PF03062.14 EXF83521.1 - 2.4e-50 171.4 5.6 2.4e-50 171.4 3.9 1.7 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family UAA PF08449.6 EXF83522.1 - 4.8e-12 45.4 19.6 5.9e-12 45.1 13.6 1.1 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EXF83522.1 - 6.7e-11 42.0 6.8 6.7e-11 42.0 4.7 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EXF83522.1 - 0.00072 19.5 5.2 0.00072 19.5 3.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family PHO4 PF01384.15 EXF83522.1 - 0.13 10.9 16.0 0.0057 15.3 6.2 2.2 1 1 1 2 2 2 0 Phosphate transporter family adh_short PF00106.20 EXF83523.1 - 3.2e-20 72.7 0.0 4.8e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF83523.1 - 8.6e-11 41.8 0.0 1.4e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF83523.1 - 1e-08 34.9 0.0 1.9e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EXF83523.1 - 3.7e-05 23.7 0.0 9.4e-05 22.4 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EXF83523.1 - 4.8e-05 22.1 0.0 7.3e-05 21.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EXF83523.1 - 0.00049 19.0 0.0 0.00068 18.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EXF83523.1 - 0.0012 17.7 0.0 0.0025 16.7 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain NmrA PF05368.8 EXF83523.1 - 0.066 12.4 0.0 0.15 11.2 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family DapB_N PF01113.15 EXF83523.1 - 0.075 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus ARD PF03079.9 EXF83524.1 - 6.1e-45 152.9 0.5 7.5e-45 152.6 0.3 1.1 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EXF83524.1 - 8.9e-09 34.7 0.1 1.6e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EXF83524.1 - 1.5e-05 24.7 0.0 2.2e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain GPI PF06560.6 EXF83524.1 - 0.0059 15.6 0.0 0.0075 15.3 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate isomerase (GPI) Cupin_1 PF00190.17 EXF83524.1 - 0.0094 15.3 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Cupin DER1 PF04511.10 EXF83525.1 - 3.9e-51 173.3 4.4 4.7e-51 173.0 3.0 1.0 1 0 0 1 1 1 1 Der1-like family Histone PF00125.19 EXF83526.1 - 3.7e-30 103.8 0.6 5.1e-30 103.4 0.4 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EXF83526.1 - 7.1e-05 22.9 0.1 0.0001 22.4 0.1 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EXF83526.1 - 0.0038 16.5 0.3 0.0041 16.4 0.2 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T CBFD_NFYB_HMF PF00808.18 EXF83526.1 - 0.0059 16.6 0.1 0.0088 16.0 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FUN14 PF04930.10 EXF83527.1 - 7 6.9 5.8 52 4.1 4.0 2.2 1 1 0 1 1 1 0 FUN14 family Peptidase_M24 PF00557.19 EXF83528.1 - 1.3e-41 142.5 0.1 1.7e-41 142.1 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EXF83528.1 - 3.7e-25 88.9 0.0 7.9e-20 71.6 0.0 2.3 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain tRNA-synt_1b PF00579.20 EXF83530.1 - 2.1e-73 247.0 0.0 2.4e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) tRNA-synt_1f PF01921.13 EXF83530.1 - 0.13 10.9 0.0 0.22 10.1 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (K) Ribosomal_S10 PF00338.17 EXF83531.1 - 5.1e-22 77.5 0.0 8.1e-22 76.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Fcf2 PF08698.6 EXF83532.1 - 1.7e-26 92.1 0.1 1.5e-25 89.0 0.0 2.1 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing Seryl_tRNA_N PF02403.17 EXF83532.1 - 0.15 12.1 0.9 0.31 11.0 0.6 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain CBFD_NFYB_HMF PF00808.18 EXF83533.1 - 1.2e-19 70.0 0.6 1.9e-19 69.4 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EXF83533.1 - 2.2e-11 43.6 0.1 3.4e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.5 EXF83533.1 - 0.021 14.6 0.0 0.031 14.0 0.0 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Sec15 PF04091.7 EXF83534.1 - 3.5e-112 374.7 4.3 3.5e-112 374.7 3.0 1.9 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like DUF4201 PF13870.1 EXF83534.1 - 0.00047 19.6 4.7 0.00047 19.6 3.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4201) DASH_Duo1 PF08651.5 EXF83534.1 - 0.56 9.8 5.9 0.44 10.1 0.7 3.1 3 0 0 3 3 3 0 DASH complex subunit Duo1 RRM_2 PF04059.7 EXF83535.1 - 1.7e-38 130.5 0.4 2.7e-38 129.8 0.3 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.17 EXF83535.1 - 0.00065 19.2 0.0 0.49 10.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF83535.1 - 0.01 15.7 0.1 1.5 8.8 0.0 2.6 2 0 0 2 2 2 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Med13_C PF06333.7 EXF83535.1 - 0.17 10.3 1.4 0.45 8.9 1.0 1.6 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal Sad1_UNC PF07738.8 EXF83536.1 - 4.5e-36 123.6 0.0 1.2e-35 122.2 0.0 1.8 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Cutinase PF01083.17 EXF83539.1 - 1.5e-34 119.2 0.1 2.3e-34 118.7 0.0 1.3 1 0 0 1 1 1 1 Cutinase Jacalin PF01419.12 EXF83539.1 - 5.8e-05 22.9 0.2 0.00015 21.6 0.1 1.6 1 1 0 1 1 1 1 Jacalin-like lectin domain DUF3089 PF11288.3 EXF83539.1 - 0.00065 18.9 0.0 0.0014 17.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3089) PE-PPE PF08237.6 EXF83539.1 - 0.01 15.2 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 PE-PPE domain VirJ PF06057.6 EXF83539.1 - 0.025 14.3 0.0 0.099 12.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) Lipase_3 PF01764.20 EXF83539.1 - 0.075 12.6 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.2 EXF83539.1 - 0.091 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2974 PF11187.3 EXF83539.1 - 0.15 11.4 0.0 0.33 10.2 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) UPF0114 PF03350.11 EXF83540.1 - 0.0066 16.3 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family, UPF0114 DUF4401 PF14351.1 EXF83540.1 - 0.023 13.6 0.5 0.032 13.2 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) ABC_membrane PF00664.18 EXF83541.1 - 4.7e-26 91.8 12.3 6.4e-26 91.3 8.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EXF83541.1 - 2.6e-16 60.1 0.2 1.2e-15 58.0 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EXF83541.1 - 2.3e-07 31.0 0.9 8.9e-05 22.5 0.2 2.5 1 1 1 2 2 2 2 AAA domain SMC_N PF02463.14 EXF83541.1 - 3.1e-05 23.3 0.0 0.00015 21.1 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 EXF83541.1 - 0.00028 20.4 0.0 0.00055 19.4 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family SbcCD_C PF13558.1 EXF83541.1 - 0.00043 20.1 0.8 0.007 16.2 0.0 2.5 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit T2SE PF00437.15 EXF83541.1 - 0.00064 18.7 0.0 0.0016 17.4 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.1 EXF83541.1 - 0.0017 18.5 0.2 0.035 14.2 0.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EXF83541.1 - 0.0043 16.5 0.1 0.01 15.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EXF83541.1 - 0.011 14.8 0.1 0.21 10.6 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin DUF258 PF03193.11 EXF83541.1 - 0.056 12.6 0.1 0.13 11.4 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EXF83541.1 - 0.12 11.7 0.4 0.56 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain P_gingi_FimA PF06321.6 EXF83541.1 - 0.16 11.1 0.1 1.2 8.2 0.0 2.0 2 0 0 2 2 2 0 Major fimbrial subunit protein (FimA) ABC_tran PF00005.22 EXF83542.1 - 9.4e-13 48.6 0.0 2.3e-12 47.4 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EXF83542.1 - 1e-11 44.8 8.4 1e-11 44.8 5.8 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_16 PF13191.1 EXF83542.1 - 0.00011 22.2 0.0 0.00025 21.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 EXF83542.1 - 0.0012 17.8 0.0 0.0021 16.9 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein UPF0079 PF02367.12 EXF83542.1 - 0.0017 17.9 0.2 0.0032 17.0 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_22 PF13401.1 EXF83542.1 - 0.0019 18.3 0.4 0.011 15.9 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EXF83542.1 - 0.003 17.4 0.0 0.0059 16.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EXF83542.1 - 0.0033 17.6 0.1 0.0076 16.4 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 EXF83542.1 - 0.0039 16.6 0.1 0.011 15.1 0.0 1.8 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EXF83542.1 - 0.0079 15.3 0.1 0.014 14.5 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EXF83542.1 - 0.0096 15.3 0.0 0.017 14.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EXF83542.1 - 0.1 12.5 0.0 0.22 11.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EXF83542.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase Rad17 PF03215.10 EXF83542.1 - 0.17 10.5 0.2 0.32 9.6 0.2 1.3 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Cyclin_N PF00134.18 EXF83543.1 - 1.5e-11 43.9 0.1 4.1e-11 42.5 0.0 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 EXF83543.1 - 0.099 12.4 0.1 0.099 12.4 0.1 1.8 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Mito_carr PF00153.22 EXF83544.1 - 7.3e-66 217.9 6.7 6.1e-24 83.5 0.1 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EXF83544.1 - 9.8e-21 73.6 4.9 3.8e-12 46.1 0.8 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EXF83544.1 - 5.5e-17 59.6 5.5 0.0001 21.3 0.8 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EXF83544.1 - 2.9e-14 51.5 4.5 0.00023 20.7 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EXF83544.1 - 1.6e-13 49.2 5.6 1.2e-05 24.3 0.4 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EXF83544.1 - 5.1e-09 35.6 5.9 0.017 14.7 0.3 3.4 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EXF83544.1 - 1.7e-08 34.4 0.3 8.6e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF3498 PF12004.3 EXF83544.1 - 0.08 12.0 9.5 0.15 11.1 6.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) TFIIA PF03153.8 EXF83544.1 - 0.11 12.3 7.7 0.18 11.7 5.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4098 PF13345.1 EXF83545.1 - 3.7e-05 23.5 6.9 1.3 9.0 0.2 5.2 4 2 0 4 4 4 3 Domain of unknown function (DUF4098) ATP_bind_3 PF01171.15 EXF83546.1 - 5.7e-40 136.7 0.0 7.2e-27 94.0 0.0 2.2 2 0 0 2 2 2 2 PP-loop family Asn_synthase PF00733.16 EXF83546.1 - 0.0066 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase PGC7_Stella PF15549.1 EXF83546.1 - 0.14 12.1 0.5 0.31 11.0 0.3 1.5 1 0 0 1 1 1 0 PGC7/Stella/Dppa3 domain Mito_carr PF00153.22 EXF83547.1 - 2.2e-48 161.9 6.8 2.3e-19 68.8 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein K-cyclin_vir_C PF09080.5 EXF83547.1 - 0.0096 16.1 0.2 0.026 14.7 0.2 1.7 1 0 0 1 1 1 1 K cyclin, C terminal DUF3337 PF11816.3 EXF83548.1 - 8.8e-93 311.2 0.0 5.5e-90 302.1 0.3 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3337) WD40 PF00400.27 EXF83548.1 - 6.6e-27 92.3 8.9 4.9e-07 29.3 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 EXF83548.1 - 0.011 13.8 0.4 0.13 10.3 0.0 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Transposase_23 PF03017.9 EXF83548.1 - 0.044 13.3 0.2 0.11 12.0 0.1 1.6 1 0 0 1 1 1 0 TNP1/EN/SPM transposase Ribosomal_60s PF00428.14 EXF83548.1 - 3.4 8.1 30.9 6.4 7.2 1.8 4.1 4 0 0 4 4 4 0 60s Acidic ribosomal protein DEAD PF00270.24 EXF83549.1 - 8.5e-43 145.7 0.0 1.5e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EXF83549.1 - 9.7e-21 73.0 0.2 2.2e-20 71.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EXF83549.1 - 5.4e-20 71.0 0.0 2.8e-19 68.7 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EXF83549.1 - 0.14 12.0 1.1 0.54 10.0 0.0 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Pox_Ag35 PF03286.9 EXF83549.1 - 0.73 9.3 14.5 1.3 8.5 10.0 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein COPI_C PF06957.6 EXF83549.1 - 1.4 7.3 8.9 2.8 6.3 6.2 1.4 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Daxx PF03344.10 EXF83549.1 - 1.7 7.0 17.8 2.4 6.5 12.3 1.1 1 0 0 1 1 1 0 Daxx Family 6PF2K PF01591.13 EXF83550.1 - 3.7e-79 264.8 0.2 4.9e-79 264.4 0.1 1.2 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EXF83550.1 - 1.6e-32 112.8 0.0 3.4e-32 111.7 0.0 1.6 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EXF83550.1 - 1.7e-09 37.6 0.0 3.7e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EXF83550.1 - 6e-05 22.3 0.0 9.1e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 EXF83550.1 - 0.00051 20.8 0.7 0.0044 17.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain Asp PF00026.18 EXF83551.1 - 8.6e-42 143.4 0.9 1.2e-41 142.9 0.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EXF83551.1 - 2.2e-06 28.0 0.4 0.087 13.3 0.1 3.5 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EXF83551.1 - 0.012 15.1 0.1 0.3 10.6 0.0 2.8 3 0 0 3 3 3 0 Xylanase inhibitor C-terminal RVP PF00077.15 EXF83551.1 - 0.044 13.6 0.1 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 Retroviral aspartyl protease DUF829 PF05705.9 EXF83552.1 - 1.4e-40 139.5 0.0 1.9e-40 139.0 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Ank_2 PF12796.2 EXF83553.1 - 2.6e-05 24.4 0.0 0.00036 20.8 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EXF83553.1 - 0.00021 21.7 0.7 0.0014 19.0 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.25 EXF83553.1 - 0.00074 19.2 0.1 0.014 15.1 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EXF83553.1 - 0.014 15.6 0.1 0.072 13.3 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF83553.1 - 0.036 14.3 0.3 0.62 10.4 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat MscS_porin PF12795.2 EXF83553.1 - 0.11 11.7 4.5 0.18 11.1 3.1 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Clr5 PF14420.1 EXF83554.1 - 1.3e-10 41.0 0.1 3.2e-10 39.7 0.1 1.7 1 0 0 1 1 1 1 Clr5 domain DUF2039 PF10217.4 EXF83555.1 - 0.054 13.5 0.5 0.054 13.5 0.4 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) KH_1 PF00013.24 EXF83556.1 - 1.2e-42 143.3 11.8 3e-14 52.4 1.0 3.4 3 0 0 3 3 3 3 KH domain KH_3 PF13014.1 EXF83556.1 - 5.7e-31 105.6 17.0 3.7e-11 42.4 0.1 3.9 4 0 0 4 4 4 3 KH domain KH_2 PF07650.12 EXF83556.1 - 3.6e-13 48.8 2.8 0.0015 18.0 0.0 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.1 EXF83556.1 - 1.6e-07 30.8 6.2 0.21 11.2 0.3 3.4 3 0 0 3 3 3 3 KH domain KH_5 PF13184.1 EXF83556.1 - 0.00041 20.0 5.2 2.1 8.2 0.6 3.9 3 1 0 3 3 3 2 NusA-like KH domain SLS PF14611.1 EXF83556.1 - 0.079 12.3 0.0 16 4.8 0.0 2.9 3 0 0 3 3 3 0 Mitochondrial inner-membrane-bound regulator Baculo_PEP_C PF04513.7 EXF83559.1 - 0.0099 15.7 13.9 0.041 13.6 0.8 3.9 3 2 1 4 4 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus Trp_syntA PF00290.15 EXF83560.1 - 1e-81 273.3 0.0 2e-81 272.3 0.0 1.4 1 0 0 1 1 1 1 Tryptophan synthase alpha chain PALP PF00291.20 EXF83560.1 - 6.5e-45 153.6 1.5 1e-44 153.0 1.1 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PcrB PF01884.12 EXF83560.1 - 0.0059 15.8 0.1 3.7 6.7 0.0 2.6 2 0 0 2 2 2 2 PcrB family Ribosomal_L28 PF00830.14 EXF83561.1 - 5.8e-18 64.4 1.9 9.3e-18 63.8 1.3 1.4 1 0 0 1 1 1 1 Ribosomal L28 family DUF3439 PF11921.3 EXF83561.1 - 0.084 12.6 3.1 0.14 11.8 2.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Tropomyosin_1 PF12718.2 EXF83562.1 - 0.071 12.9 3.2 0.26 11.1 0.3 2.3 2 0 0 2 2 2 0 Tropomyosin like Methyltransf_26 PF13659.1 EXF83562.1 - 0.14 12.2 1.0 0.71 9.9 0.0 2.4 1 1 1 2 2 2 0 Methyltransferase domain Aminotran_1_2 PF00155.16 EXF83563.1 - 4.9e-90 302.0 0.0 5.6e-90 301.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Ank_5 PF13857.1 EXF83564.1 - 5.4e-05 23.3 0.0 0.027 14.7 0.0 3.5 3 1 1 4 4 4 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EXF83564.1 - 0.00018 21.9 0.0 0.0062 17.0 0.0 3.0 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EXF83564.1 - 0.00024 21.4 0.1 0.044 14.1 0.0 3.8 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank PF00023.25 EXF83564.1 - 0.00029 20.4 0.7 2 8.3 1.0 3.9 3 1 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EXF83564.1 - 0.0011 18.9 0.8 40 4.8 0.0 5.3 6 0 0 6 6 6 0 Ankyrin repeat Baculo_PEP_C PF04513.7 EXF83564.1 - 2 8.2 9.9 1.1e+02 2.6 5.1 3.1 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus LVIVD PF08309.6 EXF83565.1 - 0.029 13.3 5.9 4.2 6.4 0.0 3.4 3 1 1 4 4 4 0 LVIVD repeat HsbA PF12296.3 EXF83567.1 - 3.6e-15 55.9 2.0 1.2e-13 51.0 0.5 2.3 2 0 0 2 2 2 2 Hydrophobic surface binding protein A Glyoxalase_2 PF12681.2 EXF83568.1 - 1.6e-15 57.5 0.0 2e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EXF83568.1 - 5.4e-07 29.6 0.1 1.3e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GMC_oxred_N PF00732.14 EXF83571.1 - 1e-62 211.9 0.0 1.3e-62 211.6 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF83571.1 - 1.4e-33 116.1 0.0 3.3e-33 115.0 0.0 1.6 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EXF83571.1 - 1.1e-07 31.1 0.1 0.00063 18.7 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EXF83571.1 - 0.00021 21.2 0.3 0.00044 20.2 0.2 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EXF83571.1 - 0.00022 21.3 0.1 0.2 11.6 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF83571.1 - 0.00032 19.7 0.2 0.00046 19.2 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EXF83571.1 - 0.00041 20.2 0.6 0.034 14.0 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF83571.1 - 0.00046 19.1 1.7 0.0029 16.5 0.2 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EXF83571.1 - 0.0054 15.2 0.8 0.044 12.2 0.1 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EXF83571.1 - 0.021 13.8 0.5 0.05 12.6 0.0 1.7 2 0 0 2 2 2 0 Thi4 family FAD_binding_3 PF01494.14 EXF83571.1 - 0.093 11.7 0.2 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 EXF83571.1 - 0.1 11.2 0.6 0.14 10.7 0.4 1.1 1 0 0 1 1 1 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EXF83571.1 - 0.13 12.0 0.1 0.27 10.9 0.1 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 EXF83571.1 - 0.27 10.0 1.6 7.3 5.3 0.1 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Cutinase PF01083.17 EXF83572.1 - 4.4e-48 163.3 0.0 5.6e-48 163.0 0.0 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EXF83572.1 - 0.00027 20.4 0.0 0.00039 19.9 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain VirJ PF06057.6 EXF83572.1 - 0.0024 17.6 0.0 0.0037 17.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial virulence protein (VirJ) Abhydrolase_5 PF12695.2 EXF83572.1 - 0.0042 16.8 0.0 0.0055 16.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF83572.1 - 0.014 14.9 0.0 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.3 EXF83572.1 - 0.022 14.1 0.0 0.031 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.20 EXF83572.1 - 0.052 13.1 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Ank_2 PF12796.2 EXF83573.1 - 4e-26 91.1 0.0 2.3e-11 43.8 0.0 3.5 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EXF83573.1 - 4.2e-20 70.4 0.2 0.0021 17.7 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EXF83573.1 - 2.9e-17 62.2 0.8 3.7e-06 26.9 0.0 5.5 4 2 2 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF83573.1 - 4.1e-17 60.5 0.1 0.0095 16.0 0.0 6.4 6 0 0 6 6 6 4 Ankyrin repeat Ank_4 PF13637.1 EXF83573.1 - 7.4e-15 55.0 1.0 7.2e-06 26.3 0.0 5.4 4 1 2 6 6 6 3 Ankyrin repeats (many copies) NACHT PF05729.7 EXF83574.1 - 0.00092 18.9 0.0 0.0016 18.1 0.0 1.4 1 1 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 EXF83574.1 - 0.01 14.8 0.2 0.02 13.8 0.1 1.4 1 1 0 1 1 1 0 KAP family P-loop domain Peroxidase_2 PF01328.12 EXF83575.1 - 2.8e-44 151.0 0.1 3.6e-44 150.7 0.1 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Epimerase PF01370.16 EXF83576.1 - 6.3e-06 25.7 0.0 0.0015 17.9 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EXF83576.1 - 0.01 14.8 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EXF83576.1 - 0.011 16.0 0.0 0.021 15.1 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DUF4381 PF14316.1 EXF83577.1 - 0.0038 17.3 1.2 0.0038 17.3 0.8 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF4381) Herpes_gE PF02480.11 EXF83577.1 - 0.092 10.9 0.0 0.17 10.1 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E AAA PF00004.24 EXF83578.1 - 1e-07 32.2 0.1 4.6e-07 30.0 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UPF0079 PF02367.12 EXF83578.1 - 0.012 15.2 2.4 0.7 9.5 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 EXF83578.1 - 0.013 15.5 0.1 0.037 14.0 0.1 1.8 1 1 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.21 EXF83578.1 - 0.026 14.0 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain T2SE PF00437.15 EXF83578.1 - 0.063 12.1 0.0 0.11 11.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein HsbA PF12296.3 EXF83580.1 - 2.5e-21 75.8 13.0 3.5e-21 75.3 9.0 1.2 1 0 0 1 1 1 1 Hydrophobic surface binding protein A DUF2379 PF09543.5 EXF83580.1 - 0.57 10.1 4.3 0.23 11.4 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2379) DUF3112 PF11309.3 EXF83581.1 - 4.5e-25 88.2 1.9 4.5e-25 88.2 1.3 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3112) Abhydrolase_3 PF07859.8 EXF83582.1 - 6.6e-57 192.4 0.1 8.6e-57 192.1 0.1 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EXF83582.1 - 6.2e-07 28.4 0.4 2.2e-06 26.6 0.3 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EXF83582.1 - 2.7e-05 23.9 0.2 3.9e-05 23.4 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EXF83582.1 - 0.0066 15.7 0.8 0.058 12.6 0.1 2.2 2 0 0 2 2 2 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EXF83582.1 - 0.018 14.2 0.1 0.07 12.3 0.0 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EXF83582.1 - 0.42 10.4 6.1 0.36 10.6 3.1 1.8 2 1 0 2 2 2 0 Alpha/beta hydrolase family Wzy_C PF04932.10 EXF83583.1 - 0.13 12.0 2.7 4.4 7.0 0.1 2.4 2 1 0 2 2 2 0 O-Antigen ligase SusD-like PF12741.2 EXF83583.1 - 0.19 10.2 0.0 0.26 9.8 0.0 1.1 1 0 0 1 1 1 0 Susd and RagB outer membrane lipoprotein DPBB_1 PF03330.13 EXF83584.1 - 2.1e-09 37.2 0.3 7.1e-09 35.5 0.0 2.1 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EXF83584.1 - 9.2e-06 25.3 0.2 1.8e-05 24.3 0.1 1.4 1 0 0 1 1 1 1 Barwin family Zip PF02535.17 EXF83588.1 - 8.7e-44 149.7 2.7 8.7e-44 149.7 1.9 1.9 2 0 0 2 2 2 1 ZIP Zinc transporter DUF1700 PF08006.6 EXF83588.1 - 0.036 13.3 4.8 1.1 8.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1700) Fungal_trans_2 PF11951.3 EXF83589.1 - 5.2e-08 31.8 0.0 7.4e-08 31.3 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EXF83589.1 - 0.05 12.4 0.0 0.096 11.5 0.0 1.4 1 0 0 1 1 1 0 Fungal specific transcription factor domain PhyH PF05721.8 EXF83590.1 - 1.5e-09 38.2 0.0 4.2e-09 36.7 0.0 1.8 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) NPP1 PF05630.6 EXF83591.1 - 6.4e-36 124.0 0.0 9.7e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) SOG2 PF10428.4 EXF83591.1 - 2.3 6.7 13.2 3.2 6.3 9.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein NPP1 PF05630.6 EXF83593.1 - 1e-30 107.0 0.0 2.5e-30 105.7 0.0 1.6 1 1 0 1 1 1 1 Necrosis inducing protein (NPP1) NPP1 PF05630.6 EXF83594.1 - 3e-36 125.1 0.0 4.2e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) SKG6 PF08693.5 EXF83595.1 - 0.0018 17.5 0.2 0.003 16.8 0.2 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF1469 PF07332.6 EXF83595.1 - 0.068 12.9 0.0 0.095 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) Podoplanin PF05808.6 EXF83595.1 - 0.27 10.7 4.3 0.16 11.5 1.5 1.7 1 1 1 2 2 2 0 Podoplanin DUF320 PF03777.8 EXF83595.1 - 5.5 6.8 9.8 14 5.5 3.4 2.7 2 1 1 3 3 3 0 Small secreted domain (DUF320) Glyco_hydro_cc PF11790.3 EXF83596.1 - 2.7e-58 197.2 0.0 3.2e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Ins_beta PF03488.9 EXF83597.1 - 0.02 14.6 1.6 0.043 13.6 1.1 1.5 1 0 0 1 1 1 0 Nematode insulin-related peptide beta type DNA_ligase_ZBD PF03119.11 EXF83597.1 - 0.17 11.5 2.4 4.7 7.0 0.7 2.5 2 0 0 2 2 2 0 NAD-dependent DNA ligase C4 zinc finger domain FMN_red PF03358.10 EXF83598.1 - 2.8e-25 88.6 0.0 3.8e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EXF83598.1 - 1.3e-05 24.8 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Flavodoxin-like fold Asp PF00026.18 EXF83599.1 - 2.9e-40 138.4 0.6 5.2e-40 137.6 0.4 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EXF83599.1 - 0.00012 22.1 1.4 0.00027 20.9 1.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal CcmD PF04995.9 EXF83599.1 - 0.03 14.0 0.1 0.058 13.1 0.1 1.4 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) DUF1049 PF06305.6 EXF83599.1 - 0.14 11.6 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Glyco_hydro_18 PF00704.23 EXF83600.1 - 8.8e-94 314.7 6.7 1e-93 314.5 4.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Methyltransf_23 PF13489.1 EXF83601.1 - 2.1e-12 47.0 0.0 4.8e-12 45.8 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF83601.1 - 2.5e-07 30.3 0.1 0.00013 21.5 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EXF83601.1 - 0.00013 22.3 0.1 0.005 17.2 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF83601.1 - 0.0011 19.5 0.4 1.1 9.8 0.0 2.9 2 2 1 3 3 3 2 Methyltransferase domain Methyltransf_11 PF08241.7 EXF83601.1 - 0.0016 18.9 0.0 0.025 15.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain DUF3530 PF12048.3 EXF83601.1 - 0.19 10.6 0.1 0.26 10.2 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) BTB PF00651.26 EXF83602.1 - 0.051 13.5 0.0 0.13 12.3 0.0 1.6 1 1 1 2 2 2 0 BTB/POZ domain DUF1411 PF07199.6 EXF83602.1 - 0.12 11.8 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) DUF3114 PF11311.3 EXF83605.1 - 0.094 12.0 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3114) N2227 PF07942.7 EXF83607.1 - 3.6e-58 196.6 0.0 4.7e-58 196.2 0.0 1.1 1 0 0 1 1 1 1 N2227-like protein Methyltransf_11 PF08241.7 EXF83607.1 - 3.9e-10 40.0 0.0 1.3e-08 35.1 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF83607.1 - 7.6e-09 35.4 0.0 1.3e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF83607.1 - 4.3e-07 30.3 0.1 1.2e-05 25.6 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF83607.1 - 2.5e-06 27.1 0.1 0.001 18.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EXF83607.1 - 1.6e-05 25.4 0.0 5.1e-05 23.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF83607.1 - 2.1e-05 24.5 0.0 6.1e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF83607.1 - 0.00013 22.2 0.0 0.00042 20.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 EXF83607.1 - 0.0071 15.8 0.1 0.026 13.9 0.1 2.0 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) MTS PF05175.9 EXF83607.1 - 0.0098 15.2 0.0 0.74 9.1 0.0 2.4 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_24 PF13578.1 EXF83607.1 - 0.013 16.3 0.0 0.026 15.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EXF83607.1 - 0.022 13.9 0.0 0.04 13.0 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Ubie_methyltran PF01209.13 EXF83607.1 - 0.038 13.1 0.0 0.099 11.7 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 EXF83607.1 - 0.051 13.1 0.0 0.13 11.8 0.0 1.6 2 0 0 2 2 2 0 Hypothetical methyltransferase Tyrosinase PF00264.15 EXF83608.1 - 2.9e-37 128.9 9.0 4e-37 128.5 6.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase DUF3328 PF11807.3 EXF83609.1 - 5.9e-31 107.8 0.0 7.8e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) LytTR PF04397.10 EXF83610.1 - 9.4e-06 25.6 4.9 8.1 6.5 0.0 5.4 1 1 6 8 8 8 6 LytTr DNA-binding domain But2 PF09792.4 EXF83612.1 - 0.00017 21.3 0.0 0.00086 19.0 0.0 2.0 1 1 0 1 1 1 1 Ubiquitin 3 binding protein But2 C-terminal domain Methyltransf_18 PF12847.2 EXF83613.1 - 3e-10 40.6 0.0 5.7e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF83613.1 - 1.3e-05 25.5 0.0 2.5e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF83613.1 - 1.5e-05 24.7 0.0 2.2e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF83613.1 - 1.7e-05 25.1 0.0 5.1e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EXF83613.1 - 4.7e-05 23.0 0.0 7.8e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.1 EXF83613.1 - 0.00035 20.1 0.2 0.00093 18.8 0.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF83613.1 - 0.0016 17.5 0.0 0.0021 17.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EXF83613.1 - 0.014 15.8 0.0 0.057 13.8 0.0 2.1 2 1 0 2 2 2 0 Methyltransferase domain MetW PF07021.7 EXF83613.1 - 0.03 13.6 0.1 0.23 10.7 0.0 2.2 3 0 0 3 3 3 0 Methionine biosynthesis protein MetW RrnaAD PF00398.15 EXF83613.1 - 0.036 13.1 0.0 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MTS PF05175.9 EXF83613.1 - 0.073 12.4 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_24 PF13578.1 EXF83613.1 - 0.08 13.7 0.0 0.16 12.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Fibrillarin PF01269.12 EXF83613.1 - 0.082 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Glyco_hydro_3 PF00933.16 EXF83615.1 - 9.7e-87 290.7 0.0 1.4e-86 290.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF83615.1 - 2e-59 200.9 0.0 1.1e-58 198.5 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF83615.1 - 8.9e-22 76.8 0.3 2.6e-21 75.3 0.1 1.9 2 0 0 2 2 2 1 Fibronectin type III-like domain PA14 PF07691.7 EXF83615.1 - 8.5e-06 25.4 0.0 1.6e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 PA14 domain CARDB PF07705.6 EXF83615.1 - 0.15 12.0 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 CARDB FtsX PF02687.16 EXF83616.1 - 0.012 15.3 2.1 0.012 15.3 1.5 3.5 1 1 1 2 2 2 0 FtsX-like permease family Cytochrom_B562 PF07361.6 EXF83618.1 - 0.027 14.8 0.2 0.1 13.0 0.1 2.0 1 0 0 1 1 1 0 Cytochrome b562 eIF_4EBP PF05456.6 EXF83618.1 - 0.069 12.8 0.1 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Pacs-1 PF10254.4 EXF83618.1 - 0.12 11.0 1.2 0.17 10.4 0.8 1.2 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein YkyA PF10368.4 EXF83618.1 - 0.14 11.5 2.7 0.11 11.7 0.2 2.0 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein FHIPEP PF00771.15 EXF83618.1 - 0.21 9.8 0.2 0.34 9.1 0.2 1.3 1 0 0 1 1 1 0 FHIPEP family Metal_resist PF13801.1 EXF83618.1 - 2.4 8.1 11.4 0.17 11.9 2.2 2.8 2 0 0 2 2 2 0 Heavy-metal resistance ADH_zinc_N PF00107.21 EXF83619.1 - 1.2e-21 76.6 0.0 1.7e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF83619.1 - 5e-20 71.2 2.3 7.8e-20 70.6 1.6 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain 2-Hacid_dh_C PF02826.14 EXF83619.1 - 0.0019 17.4 0.1 0.003 16.7 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EXF83619.1 - 0.0039 17.2 0.0 0.0059 16.7 0.0 1.2 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase MFS_1 PF07690.11 EXF83620.1 - 3.9e-15 55.4 14.3 6e-15 54.8 9.9 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily YoqO PF14037.1 EXF83621.1 - 0.062 13.4 0.2 0.1 12.7 0.0 1.5 2 0 0 2 2 2 0 YoqO-like protein DoxX_3 PF13781.1 EXF83621.1 - 9 6.7 12.2 3.6 7.9 6.2 1.9 2 1 0 2 2 2 0 DoxX-like family NAD_binding_8 PF13450.1 EXF83622.1 - 5.5e-14 51.9 0.0 1.3e-13 50.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF83622.1 - 0.00048 19.1 0.0 0.00098 18.1 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.19 EXF83622.1 - 0.0036 16.4 0.2 0.025 13.6 0.0 2.0 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_9 PF13454.1 EXF83622.1 - 0.013 15.2 0.1 0.18 11.5 0.0 2.7 2 2 2 4 4 4 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EXF83622.1 - 0.02 15.2 0.0 0.1 12.9 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF83622.1 - 0.041 13.7 0.0 0.061 13.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF83622.1 - 0.077 11.8 0.0 0.12 11.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Trp_halogenase PF04820.9 EXF83622.1 - 0.083 11.5 0.0 0.11 11.0 0.0 1.1 1 0 0 1 1 1 0 Tryptophan halogenase Thi4 PF01946.12 EXF83622.1 - 0.13 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Thi4 family FAD_binding_2 PF00890.19 EXF83623.1 - 1.2e-38 133.0 0.7 2.4e-38 132.0 0.5 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF83623.1 - 1.4e-13 50.5 4.2 1.1e-12 47.5 0.4 2.9 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.2 EXF83623.1 - 6.4e-08 32.1 1.7 1e-07 31.4 1.2 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EXF83623.1 - 1.5e-05 23.6 3.0 5.1e-05 21.9 0.1 2.4 2 1 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EXF83623.1 - 0.00032 20.6 0.3 0.0012 18.7 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF83623.1 - 0.00041 20.3 2.4 0.0013 18.7 1.7 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EXF83623.1 - 0.00065 18.8 2.6 0.0014 17.7 1.8 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EXF83623.1 - 0.0011 19.0 2.4 0.029 14.4 0.6 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF83623.1 - 0.0049 15.7 5.3 0.0049 15.7 3.7 2.6 3 0 0 3 3 3 1 Glucose inhibited division protein A GDI PF00996.13 EXF83623.1 - 0.023 12.9 0.3 0.039 12.2 0.0 1.4 2 0 0 2 2 2 0 GDP dissociation inhibitor Pyr_redox PF00070.22 EXF83623.1 - 0.13 12.6 0.6 3.9 7.9 0.5 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF83623.1 - 0.92 8.3 3.3 1.8 7.4 1.9 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_4 PF07993.7 EXF83624.1 - 3.5e-45 153.8 0.0 7.2e-45 152.8 0.0 1.5 2 0 0 2 2 2 1 Male sterility protein AMP-binding PF00501.23 EXF83624.1 - 3.4e-32 111.3 0.0 1.4e-31 109.2 0.0 1.9 1 1 0 1 1 1 1 AMP-binding enzyme Epimerase PF01370.16 EXF83624.1 - 1.9e-12 47.1 0.0 3.4e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EXF83624.1 - 5.2e-09 36.2 0.0 1.8e-08 34.5 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EXF83624.1 - 1e-06 28.7 0.1 1e-05 25.4 0.0 2.7 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EXF83624.1 - 0.00092 18.9 0.2 0.0063 16.1 0.0 2.4 2 1 0 2 2 2 1 KR domain 3Beta_HSD PF01073.14 EXF83624.1 - 0.0015 17.3 0.0 0.0031 16.2 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Transp_cyt_pur PF02133.10 EXF83625.1 - 2.2e-100 336.3 34.5 2.5e-100 336.1 23.9 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin S1FA PF04689.8 EXF83625.1 - 0.042 13.7 0.2 0.25 11.2 0.1 2.3 2 0 0 2 2 2 0 DNA binding protein S1FA Fungal_trans PF04082.13 EXF83626.1 - 4e-21 75.0 0.4 6.7e-21 74.3 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF83626.1 - 0.00011 22.0 6.0 0.00024 20.9 4.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Asp_Glu_race PF01177.17 EXF83627.1 - 4.2e-31 108.5 1.1 8e-31 107.6 0.7 1.5 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase CN_hydrolase PF00795.17 EXF83627.1 - 1.7e-20 73.1 0.0 3.1e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Amidohydro_4 PF13147.1 EXF83628.1 - 1.9e-24 87.1 0.8 2.9e-24 86.5 0.5 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EXF83628.1 - 1.1e-15 58.2 2.8 1.4e-13 51.2 2.0 2.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EXF83628.1 - 4.1e-14 52.1 0.8 1.1e-13 50.7 0.6 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EXF83628.1 - 3.2e-10 39.7 0.4 1e-05 24.9 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Urease_alpha PF00449.15 EXF83628.1 - 0.016 15.3 1.7 0.03 14.4 0.4 2.1 2 0 0 2 2 2 0 Urease alpha-subunit, N-terminal domain HET PF06985.6 EXF83629.1 - 1e-21 77.5 0.0 2.1e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Abhydrolase_6 PF12697.2 EXF83630.1 - 1.1e-20 74.5 0.0 1.3e-20 74.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF83630.1 - 1.4e-15 57.4 0.0 1.6e-13 50.7 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF83630.1 - 1.1e-07 31.6 0.0 5.3e-07 29.4 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EXF83630.1 - 0.0002 19.9 0.0 0.00045 18.8 0.0 1.6 1 1 0 1 1 1 1 Ndr family p450 PF00067.17 EXF83633.1 - 3.9e-41 141.0 0.0 7.6e-38 130.2 0.0 3.2 1 1 0 1 1 1 1 Cytochrome P450 V_ATPase_I PF01496.14 EXF83634.1 - 0.013 13.4 0.1 0.017 12.9 0.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Microtub_assoc PF07989.6 EXF83634.1 - 0.02 14.7 7.6 0.052 13.3 4.5 2.1 1 1 1 2 2 2 0 Microtubule associated RAP1 PF07218.6 EXF83634.1 - 0.12 10.4 0.5 0.2 9.6 0.4 1.3 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) APG6 PF04111.7 EXF83634.1 - 0.41 9.6 4.7 0.65 8.9 3.2 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 bZIP_1 PF00170.16 EXF83634.1 - 1.1 9.2 10.2 0.54 10.2 1.8 3.2 2 1 1 3 3 3 0 bZIP transcription factor SlyX PF04102.7 EXF83634.1 - 2.6 8.4 6.3 10 6.5 4.4 2.1 1 0 0 1 1 1 0 SlyX Cep57_CLD_2 PF14197.1 EXF83634.1 - 8.2 6.4 12.6 0.66 9.9 4.8 2.1 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 Peptidase_S15 PF02129.13 EXF83636.1 - 6.7e-34 117.5 3.2 9.5e-29 100.6 0.0 2.1 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EXF83636.1 - 4.1e-29 102.0 0.0 7.5e-29 101.1 0.0 1.4 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 EXF83636.1 - 0.001 19.0 0.1 0.0018 18.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PhyH PF05721.8 EXF83637.1 - 0.00012 22.1 0.1 0.00017 21.7 0.1 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 EXF83637.1 - 0.0057 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Putative 2OG-Fe(II) oxygenase DUF1479 PF07350.7 EXF83637.1 - 0.018 13.5 0.0 0.33 9.3 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1479) MFS_1 PF07690.11 EXF83638.1 - 3e-19 68.9 20.4 3e-19 68.9 14.2 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF83638.1 - 3.7e-08 32.4 4.6 3.7e-08 32.4 3.2 2.4 2 0 0 2 2 2 1 Sugar (and other) transporter DUF4191 PF13829.1 EXF83638.1 - 0.042 12.9 0.1 0.042 12.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Fungal_trans PF04082.13 EXF83639.1 - 3.2e-12 45.8 0.0 5.8e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF83639.1 - 1e-08 34.9 10.2 2e-08 33.9 7.1 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain KcnmB2_inactiv PF09303.5 EXF83639.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 KCNMB2, ball and chain domain Peroxidase_2 PF01328.12 EXF83640.1 - 1.3e-44 152.1 0.3 1.7e-44 151.7 0.2 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Aa_trans PF01490.13 EXF83641.1 - 3.6e-34 117.9 31.4 4.2e-34 117.7 21.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Spore_permease PF03845.8 EXF83641.1 - 0.028 13.1 25.7 0.0042 15.7 11.9 2.6 2 1 0 2 2 2 0 Spore germination protein BTB PF00651.26 EXF83642.1 - 0.0003 20.7 0.0 0.00063 19.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain AIG2 PF06094.7 EXF83643.1 - 1.2e-08 35.4 1.0 1.6e-07 31.7 0.1 2.3 2 0 0 2 2 2 1 AIG2-like family zf-RING_2 PF13639.1 EXF83644.1 - 1.7e-14 53.3 7.2 2.4e-14 52.8 5.0 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EXF83644.1 - 9.8e-11 41.5 7.3 1.5e-10 40.9 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EXF83644.1 - 3.8e-10 39.2 3.9 6.1e-10 38.5 2.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EXF83644.1 - 1e-08 34.7 3.3 1.5e-08 34.1 2.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EXF83644.1 - 1.5e-08 34.2 3.6 2.4e-08 33.5 2.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EXF83644.1 - 7.9e-06 25.6 7.5 2.1e-05 24.3 5.2 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EXF83644.1 - 0.00012 21.7 4.9 0.00024 20.7 3.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EXF83644.1 - 0.00016 21.7 7.7 0.00056 19.9 5.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EXF83644.1 - 0.00053 19.7 0.9 0.00082 19.1 0.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1469 PF07332.6 EXF83644.1 - 0.0038 16.9 0.2 0.0057 16.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1469) Rad50_zn_hook PF04423.9 EXF83644.1 - 0.0065 15.9 0.4 0.83 9.1 0.0 2.2 2 0 0 2 2 2 1 Rad50 zinc hook motif Prok-RING_4 PF14447.1 EXF83644.1 - 0.0088 15.5 7.8 0.042 13.4 5.4 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 FdhE PF04216.7 EXF83644.1 - 0.028 14.1 2.4 0.042 13.5 1.7 1.2 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation Vps39_2 PF10367.4 EXF83644.1 - 0.041 14.0 1.4 0.046 13.9 0.3 1.6 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-RING_4 PF14570.1 EXF83644.1 - 0.052 13.1 6.3 0.29 10.7 4.5 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF2225 PF09986.4 EXF83644.1 - 0.091 12.2 0.3 1.7 8.0 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-RING_3 PF14369.1 EXF83644.1 - 0.1 12.6 1.9 4.3 7.4 0.0 2.4 2 0 0 2 2 2 0 zinc-finger C1_3 PF07649.7 EXF83644.1 - 0.15 12.1 0.5 0.15 12.1 0.4 1.8 2 0 0 2 2 1 0 C1-like domain FYVE PF01363.16 EXF83644.1 - 0.19 11.6 4.9 0.96 9.3 3.4 2.0 1 1 0 1 1 1 0 FYVE zinc finger zf-P11 PF03854.9 EXF83644.1 - 0.29 10.6 5.9 0.2 11.1 2.2 2.0 2 0 0 2 2 2 0 P-11 zinc finger zf-HIT PF04438.11 EXF83644.1 - 0.37 10.4 3.0 0.35 10.5 0.3 2.1 2 0 0 2 2 2 0 HIT zinc finger zf-RING_6 PF14835.1 EXF83644.1 - 1 9.2 6.5 3.9 7.3 4.5 1.9 1 1 0 1 1 1 0 zf-RING of BARD1-type protein IBR PF01485.16 EXF83644.1 - 1.9 8.4 4.9 7.6 6.4 2.3 2.3 2 1 1 3 3 3 0 IBR domain PGAP1 PF07819.8 EXF83646.1 - 0.00031 20.3 0.0 0.00076 19.1 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EXF83646.1 - 0.00075 19.4 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF83646.1 - 0.033 13.9 0.1 0.11 12.2 0.1 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Asp PF00026.18 EXF83647.1 - 1.8e-39 135.8 1.3 2.3e-39 135.4 0.9 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EXF83647.1 - 7.7e-06 25.9 0.6 0.0001 22.2 0.2 2.9 4 1 0 4 4 4 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EXF83647.1 - 0.0064 16.9 0.9 4.2 7.9 0.0 3.2 3 1 1 4 4 4 2 Aspartyl protease Glyco_hydro_2_N PF02837.13 EXF83648.1 - 1.7e-32 112.3 0.1 3.9e-31 107.8 0.0 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2_C PF02836.12 EXF83648.1 - 3.3e-28 98.4 0.0 5.1e-27 94.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain Glyco_hydro_2 PF00703.16 EXF83648.1 - 4.7e-13 49.5 0.1 1.3e-12 48.1 0.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 BetaGal_dom4_5 PF13364.1 EXF83648.1 - 6.7e-06 26.3 0.1 0.00021 21.4 0.0 3.2 3 0 0 3 3 3 1 Beta-galactosidase jelly roll domain Big_1 PF02369.11 EXF83648.1 - 0.038 13.9 0.1 0.038 13.9 0.1 3.2 4 1 0 4 4 4 0 Bacterial Ig-like domain (group 1) Acetyltransf_7 PF13508.1 EXF83650.1 - 6.7e-07 29.3 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EXF83650.1 - 3.2e-06 27.0 0.0 5.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_1 PF00583.19 EXF83651.1 - 0.00016 21.5 0.0 0.001 19.0 0.0 2.2 2 1 0 2 2 2 1 Acetyltransferase (GNAT) family LCCL PF03815.14 EXF83652.1 - 5.2e-21 74.4 0.0 9.2e-21 73.6 0.0 1.3 1 0 0 1 1 1 1 LCCL domain YibE_F PF07907.6 EXF83652.1 - 0.031 13.4 0.3 0.082 12.0 0.2 1.6 1 0 0 1 1 1 0 YibE/F-like protein Sugar_tr PF00083.19 EXF83654.1 - 6.8e-70 235.8 21.6 8e-70 235.6 15.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF83654.1 - 7.3e-26 90.7 27.0 9.9e-26 90.2 18.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EXF83654.1 - 3.8e-06 25.5 0.6 3.8e-06 25.5 0.4 2.9 3 1 1 4 4 4 2 MFS/sugar transport protein MFS_1_like PF12832.2 EXF83654.1 - 0.00063 19.4 1.2 1 9.2 0.0 2.7 2 0 0 2 2 2 2 MFS_1 like family Flavin_Reduct PF01613.13 EXF83656.1 - 5.1e-25 88.1 0.0 6.9e-25 87.6 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain Peptidase_S8 PF00082.17 EXF83657.1 - 3.3e-43 147.8 14.5 3.3e-43 147.8 10.0 1.5 2 0 0 2 2 2 1 Subtilase family Inhibitor_I9 PF05922.11 EXF83657.1 - 3.8e-15 56.2 0.2 3.8e-15 56.2 0.1 1.7 2 0 0 2 2 2 1 Peptidase inhibitor I9 Abhydrolase_6 PF12697.2 EXF83660.1 - 1.4e-14 54.4 1.7 2.2e-14 53.9 1.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF83660.1 - 3.2e-13 49.6 0.4 8.5e-13 48.2 0.3 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF83660.1 - 1.5e-05 24.3 0.9 0.066 12.4 0.2 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EXF83660.1 - 4.3e-05 23.1 0.2 0.1 12.1 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold LIP PF03583.9 EXF83660.1 - 0.00013 21.2 1.1 0.0013 18.0 0.7 2.1 1 1 0 1 1 1 1 Secretory lipase DLH PF01738.13 EXF83660.1 - 0.00099 18.4 0.2 0.049 12.8 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Hydrolase_4 PF12146.3 EXF83660.1 - 0.022 14.6 0.2 0.093 12.5 0.1 2.1 1 1 0 1 1 1 0 Putative lysophospholipase PAS_9 PF13426.1 EXF83662.1 - 9.9e-20 70.8 0.1 3.9e-15 56.1 0.0 3.0 3 0 0 3 3 3 2 PAS domain RGS PF00615.14 EXF83662.1 - 8.9e-12 45.1 0.2 2.3e-11 43.8 0.2 1.6 1 0 0 1 1 1 1 Regulator of G protein signaling domain PAS_4 PF08448.5 EXF83662.1 - 0.0048 16.9 0.3 3.9 7.5 0.0 3.2 3 0 0 3 3 3 2 PAS fold Glyco_hydro_61 PF03443.9 EXF83663.1 - 0.0078 16.0 0.0 0.042 13.6 0.0 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 61 Wzt_C PF14524.1 EXF83663.1 - 0.034 13.8 0.0 0.049 13.3 0.0 1.5 1 1 0 1 1 1 0 Wzt C-terminal domain NPCBM_assoc PF10633.4 EXF83663.1 - 0.13 12.3 0.9 0.41 10.7 0.0 2.2 3 0 0 3 3 3 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Big_3_4 PF13754.1 EXF83663.1 - 0.28 11.5 2.6 0.66 10.3 1.7 1.7 1 1 0 1 1 1 0 Bacterial Ig-like domain (group 3) HAD_2 PF13419.1 EXF83664.1 - 5.3e-31 108.1 0.1 6.4e-31 107.9 0.1 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EXF83664.1 - 5.4e-08 32.4 0.0 9.1e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EXF83664.1 - 1.9e-05 25.1 0.0 2.2e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase ATP-grasp_4 PF13535.1 EXF83664.1 - 0.031 13.9 0.0 0.46 10.2 0.0 2.6 2 2 1 3 3 3 0 ATP-grasp domain Acid_PPase PF12689.2 EXF83664.1 - 0.057 13.0 0.0 0.075 12.6 0.0 1.2 1 0 0 1 1 1 0 Acid Phosphatase Glyco_hydro_7 PF00840.15 EXF83665.1 - 4.3e-209 694.2 27.0 4.9e-209 694.0 18.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Colipase-like PF15083.1 EXF83665.1 - 0.028 14.3 0.2 0.08 12.8 0.1 1.7 1 0 0 1 1 1 0 Colipase-like DUF3129 PF11327.3 EXF83666.1 - 1.5e-56 191.1 15.0 1.5e-56 191.1 10.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3129) DUF1264 PF06884.6 EXF83667.1 - 6.8e-74 246.9 0.2 8e-74 246.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) TMEM240 PF15207.1 EXF83667.1 - 0.13 11.7 0.1 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 TMEM240 family Fungal_trans PF04082.13 EXF83669.1 - 3.1e-17 62.3 0.9 3.1e-17 62.3 0.6 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain Adeno_52K PF03052.10 EXF83669.1 - 0.12 11.5 0.0 0.32 10.2 0.0 1.7 1 0 0 1 1 1 0 Adenoviral protein L1 52/55-kDa CN_hydrolase PF00795.17 EXF83670.1 - 7.9e-31 106.8 0.3 1e-30 106.4 0.2 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase FAD_binding_4 PF01565.18 EXF83672.1 - 1.6e-26 92.4 0.1 3e-26 91.5 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain FAD-oxidase_C PF02913.14 EXF83672.1 - 2.9e-22 79.1 0.0 4.6e-22 78.5 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain Trp_DMAT PF11991.3 EXF83673.1 - 1.3e-79 268.0 0.0 1.7e-79 267.6 0.0 1.0 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase ABM PF03992.11 EXF83674.1 - 0.088 12.8 0.1 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase NmrA PF05368.8 EXF83675.1 - 2.3e-16 59.7 0.2 5.8e-16 58.4 0.1 1.6 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF83675.1 - 1e-14 54.9 0.0 1.5e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF83675.1 - 0.0013 18.2 0.0 0.0027 17.2 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EXF83675.1 - 0.0025 17.7 0.2 0.0078 16.1 0.1 1.8 2 0 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EXF83675.1 - 0.03 14.6 0.4 0.16 12.3 0.1 2.2 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EXF83675.1 - 0.033 13.1 0.2 0.048 12.6 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase DUF924 PF06041.6 EXF83677.1 - 1.3e-52 178.2 0.9 1.9e-52 177.7 0.6 1.2 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) DCP2 PF05026.8 EXF83677.1 - 0.036 13.9 0.5 0.53 10.2 0.1 2.5 2 0 0 2 2 2 0 Dcp2, box A domain Glyco_hydro_11 PF00457.12 EXF83678.1 - 1.7e-72 242.6 18.6 2e-72 242.3 12.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 Cu_amine_oxid PF01179.15 EXF83679.1 - 1.2e-162 541.4 0.0 1.5e-162 541.0 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EXF83679.1 - 1.2e-08 34.8 0.0 4.2e-08 33.1 0.0 2.0 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EXF83679.1 - 5.9e-08 32.7 0.0 1.3e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain AA_permease_2 PF13520.1 EXF83680.1 - 8.3e-63 212.3 37.8 1e-62 212.0 26.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF83680.1 - 4e-23 81.5 36.1 5.6e-23 81.0 25.0 1.1 1 0 0 1 1 1 1 Amino acid permease DUF2448 PF10476.4 EXF83680.1 - 0.045 13.2 0.2 0.098 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) Fungal_trans PF04082.13 EXF83681.1 - 4.9e-11 41.9 0.0 1.1e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF83681.1 - 1.2e-06 28.2 7.5 1.2e-06 28.2 5.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DEAD PF00270.24 EXF83682.1 - 2e-45 154.2 0.0 6.2e-43 146.2 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF83682.1 - 4e-21 74.6 0.1 1.7e-20 72.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EXF83682.1 - 4.1e-05 23.4 0.0 6.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.1 EXF83682.1 - 0.0064 16.2 0.3 0.03 14.0 0.1 2.2 2 0 0 2 2 2 1 Part of AAA domain Helicase_RecD PF05127.9 EXF83682.1 - 0.0068 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Helicase AAA_30 PF13604.1 EXF83682.1 - 0.046 13.2 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EXF83682.1 - 0.056 13.0 0.0 1.7 8.1 0.0 2.2 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.1 EXF83682.1 - 0.065 13.3 0.8 0.3 11.2 0.6 2.1 1 1 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EXF83682.1 - 0.093 11.6 0.0 0.22 10.4 0.0 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) SecA_DEAD PF07517.9 EXF83682.1 - 0.12 11.6 0.0 0.24 10.6 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain Fungal_trans PF04082.13 EXF83683.1 - 1.4e-13 50.3 1.0 2.3e-13 49.6 0.7 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF83683.1 - 5.1e-08 32.7 11.5 8e-08 32.0 8.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CDK5_activator PF03261.10 EXF83683.1 - 1.3 8.2 5.9 6.2 6.0 0.7 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein PRKCSH PF07915.8 EXF83684.1 - 1.9e-20 73.4 0.4 1.9e-20 73.4 0.3 2.5 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.1 EXF83684.1 - 0.014 14.8 0.0 1.2 8.5 0.0 2.3 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein Pkinase PF00069.20 EXF83686.1 - 3.5e-19 68.9 0.0 6.6e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF83686.1 - 0.0011 18.1 0.0 0.0019 17.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase VWA PF00092.23 EXF83686.1 - 0.081 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain Abhydrolase_6 PF12697.2 EXF83688.1 - 3.3e-19 69.6 0.1 6.1e-19 68.7 0.1 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF83688.1 - 2.8e-13 49.9 0.1 1e-07 31.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF83688.1 - 1.2e-08 34.8 0.2 1.7e-08 34.3 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EXF83688.1 - 4.3e-07 29.6 0.7 7.8e-07 28.8 0.5 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Peptidase_S9 PF00326.16 EXF83688.1 - 0.082 12.1 1.3 0.25 10.5 0.9 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family DUF161 PF02588.10 EXF83688.1 - 0.092 13.0 0.7 0.24 11.7 0.5 1.7 1 0 0 1 1 1 0 Uncharacterized BCR, YitT family COG1284 ABC_tran PF00005.22 EXF83689.1 - 7.2e-42 142.9 0.0 8.3e-24 84.4 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EXF83689.1 - 2.8e-32 112.2 31.8 2.3e-15 56.7 5.8 4.2 4 0 0 4 4 4 3 ABC transporter transmembrane region SMC_N PF02463.14 EXF83689.1 - 1.2e-13 50.7 0.9 1.3e-05 24.5 0.0 4.1 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EXF83689.1 - 4.5e-10 39.9 0.0 0.014 15.4 0.0 4.2 3 1 1 4 4 4 2 AAA domain AAA_23 PF13476.1 EXF83689.1 - 3.3e-08 34.0 0.3 1.2e-05 25.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EXF83689.1 - 3e-07 30.5 1.0 0.028 14.3 0.0 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_25 PF13481.1 EXF83689.1 - 1.1e-06 28.1 0.0 0.004 16.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EXF83689.1 - 1.8e-06 27.4 0.3 0.034 13.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EXF83689.1 - 2.9e-05 24.2 0.2 0.091 12.9 0.0 3.3 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 EXF83689.1 - 3.5e-05 22.8 0.1 0.15 10.9 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF258 PF03193.11 EXF83689.1 - 7.3e-05 22.0 0.0 0.31 10.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_10 PF12846.2 EXF83689.1 - 0.00013 21.5 0.2 0.56 9.5 0.0 2.6 2 0 0 2 2 2 2 AAA-like domain NACHT PF05729.7 EXF83689.1 - 0.00077 19.1 1.4 0.62 9.6 0.2 2.8 2 0 0 2 2 2 2 NACHT domain MMR_HSR1 PF01926.18 EXF83689.1 - 0.00091 19.1 0.0 0.35 10.8 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EXF83689.1 - 0.0011 19.5 0.1 0.48 10.9 0.0 3.3 3 0 0 3 3 3 1 Miro-like protein Arch_ATPase PF01637.13 EXF83689.1 - 0.0015 18.2 0.2 0.034 13.8 0.0 2.6 3 0 0 3 3 2 1 Archaeal ATPase FtsK_SpoIIIE PF01580.13 EXF83689.1 - 0.0019 17.7 0.5 1 8.7 0.2 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family DUF87 PF01935.12 EXF83689.1 - 0.0021 17.9 3.6 0.016 15.0 0.5 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 cobW PF02492.14 EXF83689.1 - 0.0024 17.3 0.4 0.068 12.6 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.1 EXF83689.1 - 0.0037 17.1 0.1 0.49 10.3 0.0 2.9 3 0 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 EXF83689.1 - 0.0058 16.3 2.8 2.5 7.9 0.0 3.1 3 0 0 3 3 2 1 Part of AAA domain AAA PF00004.24 EXF83689.1 - 0.006 16.7 0.4 8.9 6.5 0.0 3.5 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EXF83689.1 - 0.018 15.3 0.0 9.7 6.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain Pox_A32 PF04665.7 EXF83689.1 - 0.021 14.1 0.0 5.4 6.2 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein Dynamin_N PF00350.18 EXF83689.1 - 0.053 13.3 0.8 5.2 6.8 0.1 2.4 2 0 0 2 2 2 0 Dynamin family AAA_17 PF13207.1 EXF83689.1 - 0.082 13.7 0.0 7.3 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EXF83689.1 - 0.092 12.6 0.0 14 5.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.4 EXF83689.1 - 0.098 11.6 0.3 5.1 5.9 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) UPF0079 PF02367.12 EXF83689.1 - 0.11 12.1 0.1 0.72 9.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Zeta_toxin PF06414.7 EXF83689.1 - 0.13 11.2 0.2 7 5.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_15 PF13175.1 EXF83689.1 - 0.21 10.5 0.0 0.34 9.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 EXF83689.1 - 0.25 11.5 0.0 17 5.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase MobB PF03205.9 EXF83689.1 - 0.25 11.0 0.3 25 4.5 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ABC_ATPase PF09818.4 EXF83689.1 - 0.32 9.5 0.5 1.5 7.3 0.0 2.1 2 0 0 2 2 2 0 Predicted ATPase of the ABC class PduV-EutP PF10662.4 EXF83689.1 - 0.7 9.3 1.9 2.9 7.3 0.1 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_13 PF13166.1 EXF83689.1 - 1 7.7 0.0 34 2.6 0.0 2.6 3 0 0 3 3 3 0 AAA domain NOA36 PF06524.7 EXF83689.1 - 1.2 8.3 0.6 2 7.5 0.4 1.2 1 0 0 1 1 1 0 NOA36 protein p450 PF00067.17 EXF83690.1 - 5.5e-53 180.1 0.0 7.3e-53 179.7 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 CBM_1 PF00734.13 EXF83691.1 - 1.9e-12 46.5 9.3 7e-12 44.7 6.5 2.1 1 0 0 1 1 1 1 Fungal cellulose binding domain DUF1025 PF06262.6 EXF83691.1 - 0.16 11.7 0.1 0.33 10.7 0.1 1.4 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase Peptidase_M66 PF10462.4 EXF83691.1 - 2 7.2 7.0 0.63 8.8 0.6 2.6 2 1 1 3 3 3 0 Peptidase M66 Nucleos_tra2_C PF07662.8 EXF83692.1 - 4.1e-66 222.4 2.7 4.1e-66 222.4 1.9 2.3 2 1 0 2 2 2 1 Na+ dependent nucleoside transporter C-terminus Nucleos_tra2_N PF01773.15 EXF83692.1 - 1.8e-24 85.8 1.1 1.2e-23 83.2 0.8 2.5 1 0 0 1 1 1 1 Na+ dependent nucleoside transporter N-terminus DUF202 PF02656.10 EXF83692.1 - 9.6 6.5 8.0 3.1 8.0 0.0 4.0 5 0 0 5 5 5 0 Domain of unknown function (DUF202) Sugar_tr PF00083.19 EXF83693.1 - 2.2e-68 230.8 29.6 2.6e-68 230.6 20.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF83693.1 - 6.8e-21 74.3 36.4 3e-20 72.2 23.0 2.6 2 1 1 3 3 3 1 Major Facilitator Superfamily MFS_2 PF13347.1 EXF83693.1 - 0.00044 18.7 32.1 0.011 14.2 2.0 4.1 2 2 2 4 4 4 3 MFS/sugar transport protein MFS_1_like PF12832.2 EXF83693.1 - 0.005 16.6 7.9 0.33 10.7 0.1 4.1 4 1 0 4 4 4 1 MFS_1 like family Bac_rhamnosid PF05592.6 EXF83694.1 - 3.8e-23 81.4 0.0 4e-22 78.1 0.0 2.2 1 1 0 1 1 1 1 Bacterial alpha-L-rhamnosidase Glyco_hydro_28 PF00295.12 EXF83695.1 - 2.1e-31 109.1 9.9 2.1e-31 109.1 6.9 1.8 1 1 1 2 2 2 2 Glycosyl hydrolases family 28 DUF1162 PF06650.7 EXF83697.1 - 6e-90 301.2 0.0 2.1e-87 292.8 0.0 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EXF83697.1 - 2.3e-41 140.0 1.4 3.9e-41 139.2 0.0 2.3 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EXF83697.1 - 1.6e-06 28.2 0.1 2.3e-05 24.4 0.0 2.9 3 0 0 3 3 3 1 ATG C terminal domain DUF3429 PF11911.3 EXF83698.1 - 1.5e-39 135.2 6.2 2.5e-39 134.4 4.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3429) Zip PF02535.17 EXF83699.1 - 0.19 10.6 4.5 0.16 10.9 3.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FAM74 PF15026.1 EXF83701.1 - 0.059 13.0 0.1 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 FAM74 protein TauD PF02668.11 EXF83702.1 - 1.2e-51 175.9 0.2 1.4e-51 175.6 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DUF3600 PF12207.3 EXF83702.1 - 0.19 11.2 0.0 18 4.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3600) Sld5 PF05916.6 EXF83703.1 - 2.1e-12 47.2 0.0 3e-12 46.7 0.0 1.2 1 0 0 1 1 1 1 GINS complex protein Sod_Fe_C PF02777.13 EXF83704.1 - 5.8e-42 141.8 0.2 1.3e-41 140.7 0.1 1.5 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EXF83704.1 - 1.6e-30 105.1 1.6 2.7e-30 104.4 1.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain HET PF06985.6 EXF83706.1 - 1.5e-22 80.2 0.1 2.5e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) CAAD PF14159.1 EXF83707.1 - 1.4 8.6 6.5 0.19 11.3 0.3 2.5 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase bZIP_1 PF00170.16 EXF83708.1 - 6.9e-09 35.5 8.4 6.9e-09 35.5 5.8 1.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_Maf PF03131.12 EXF83708.1 - 0.0092 16.2 4.7 0.017 15.3 3.3 1.4 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.10 EXF83708.1 - 0.027 14.3 12.7 0.12 12.1 8.8 2.0 1 1 0 1 1 1 0 Basic region leucine zipper FAD_binding_4 PF01565.18 EXF83709.1 - 2.1e-31 108.2 0.1 4.4e-31 107.1 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF83709.1 - 2.5e-05 24.0 0.0 5.9e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like Fungal_trans_2 PF11951.3 EXF83710.1 - 2.4e-08 33.0 0.6 6.4e-06 25.0 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain adh_short PF00106.20 EXF83711.1 - 5.5e-14 52.4 0.0 9.1e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF83711.1 - 5.5e-07 29.4 0.0 1.3e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF83711.1 - 0.00096 18.6 0.0 0.0013 18.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EXF83711.1 - 0.092 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase OPT PF03169.10 EXF83712.1 - 1.3e-176 588.7 53.6 1.5e-176 588.5 37.2 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein AA_permease PF00324.16 EXF83716.1 - 5.5e-140 466.8 39.6 6.8e-140 466.5 27.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF83716.1 - 4.6e-39 134.1 42.4 5.6e-39 133.8 29.4 1.1 1 0 0 1 1 1 1 Amino acid permease Defensin_big PF14862.1 EXF83716.1 - 0.11 12.6 0.1 0.11 12.6 0.1 2.1 2 0 0 2 2 2 0 Big defensin zf-C2H2_6 PF13912.1 EXF83717.1 - 0.0084 15.9 0.3 0.015 15.1 0.2 1.4 1 0 0 1 1 1 1 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF83717.1 - 0.022 15.0 0.3 0.051 13.9 0.2 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type adh_short PF00106.20 EXF83718.1 - 2.7e-12 46.8 0.0 4.4e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF83718.1 - 2e-05 24.3 0.0 5.9e-05 22.8 0.0 1.6 2 0 0 2 2 2 1 KR domain NAD_binding_4 PF07993.7 EXF83718.1 - 0.0046 15.9 0.1 0.014 14.3 0.1 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EXF83718.1 - 0.0062 16.5 0.0 0.019 14.9 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EXF83718.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 EXF83718.1 - 0.012 15.0 0.0 0.029 13.7 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EXF83718.1 - 0.018 15.1 0.0 0.027 14.5 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase adh_short_C2 PF13561.1 EXF83718.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.4 2 0 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase DUF3425 PF11905.3 EXF83719.1 - 1.2e-25 89.9 0.4 2e-25 89.2 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3425) bZIP_1 PF00170.16 EXF83719.1 - 0.015 15.2 4.4 0.031 14.2 3.1 1.4 1 0 0 1 1 1 0 bZIP transcription factor NmrA PF05368.8 EXF83720.1 - 1.4e-22 80.0 0.0 1.8e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF83720.1 - 0.00068 19.6 0.0 0.0036 17.3 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EXF83720.1 - 0.0083 15.5 0.1 0.059 12.8 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EXF83720.1 - 0.021 14.7 0.0 0.032 14.1 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase KR PF08659.5 EXF83720.1 - 0.043 13.4 0.0 0.072 12.7 0.0 1.3 1 0 0 1 1 1 0 KR domain Methyltransf_2 PF00891.13 EXF83721.1 - 2.3e-19 69.5 0.0 6.7e-19 68.0 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Arginase PF00491.16 EXF83722.1 - 1.6e-30 106.3 0.0 1.9e-30 106.1 0.0 1.0 1 0 0 1 1 1 1 Arginase family Condensation PF00668.15 EXF83723.1 - 2e-79 266.6 0.1 3.2e-29 101.7 0.3 3.8 3 1 0 3 3 3 3 Condensation domain AMP-binding PF00501.23 EXF83723.1 - 2.4e-38 131.6 0.0 5e-38 130.5 0.0 1.5 2 0 0 2 2 2 1 AMP-binding enzyme PP-binding PF00550.20 EXF83723.1 - 1e-14 54.5 0.0 0.00012 22.2 0.0 4.9 4 0 0 4 4 4 3 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EXF83723.1 - 1.2e-06 29.3 0.1 0.2 12.6 0.0 3.9 4 0 0 4 4 4 2 AMP-binding enzyme C-terminal domain Abhydrolase_3 PF07859.8 EXF83724.1 - 1.3e-29 103.2 0.0 2.8e-29 102.2 0.0 1.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.23 EXF83724.1 - 0.0013 17.5 0.0 0.0026 16.5 0.0 1.4 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_2 PF02230.11 EXF83724.1 - 0.012 15.1 0.0 0.019 14.4 0.0 1.3 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF2424 PF10340.4 EXF83724.1 - 0.02 13.5 0.0 0.16 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EXF83724.1 - 0.093 11.9 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family SAPS PF04499.10 EXF83725.1 - 1.5e-164 548.1 0.0 5.5e-162 539.7 0.0 3.0 2 1 0 2 2 2 2 SIT4 phosphatase-associated protein Sugar_tr PF00083.19 EXF83726.1 - 3.6e-114 381.8 27.8 4.2e-114 381.5 19.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF83726.1 - 1.5e-20 73.2 55.2 2.1e-17 62.9 19.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EXF83726.1 - 4e-06 25.4 29.5 0.0002 19.9 8.7 3.6 3 1 0 3 3 3 3 MFS/sugar transport protein Fungal_trans PF04082.13 EXF83727.1 - 3.2e-08 32.7 0.4 4.5e-08 32.2 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC_tran PF00005.22 EXF83728.1 - 1.3e-43 148.5 0.0 1.1e-26 93.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EXF83728.1 - 1.9e-23 83.2 2.7 1.9e-23 83.2 1.8 4.2 5 0 0 5 5 4 2 ABC transporter transmembrane region Asp_Glu_race PF01177.17 EXF83728.1 - 4.2e-17 62.7 0.0 9.3e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Asp/Glu/Hydantoin racemase SMC_N PF02463.14 EXF83728.1 - 1.7e-12 47.0 2.2 0.02 14.1 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EXF83728.1 - 4.1e-10 40.1 0.1 0.02 14.8 0.0 4.3 3 1 1 4 4 4 2 AAA domain AAA_22 PF13401.1 EXF83728.1 - 1.7e-08 34.6 0.0 0.011 15.9 0.0 3.0 2 2 0 2 2 2 2 AAA domain AAA PF00004.24 EXF83728.1 - 5.6e-07 29.8 0.1 0.1 12.7 0.0 3.7 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EXF83728.1 - 3.7e-06 26.2 0.2 0.054 12.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 T2SE PF00437.15 EXF83728.1 - 9.6e-05 21.4 0.2 0.048 12.5 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein Miro PF08477.8 EXF83728.1 - 0.00011 22.6 0.1 0.18 12.3 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein AAA_33 PF13671.1 EXF83728.1 - 0.0002 21.2 0.1 0.46 10.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EXF83728.1 - 0.00035 20.6 3.2 0.26 11.2 0.2 3.3 2 2 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.1 EXF83728.1 - 0.0005 20.4 0.2 0.49 10.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain SbcCD_C PF13558.1 EXF83728.1 - 0.00052 19.8 0.1 1.7 8.6 0.1 2.8 2 0 0 2 2 2 2 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.17 EXF83728.1 - 0.0007 18.5 0.1 0.0034 16.2 0.0 2.1 2 0 0 2 2 2 1 NB-ARC domain MobB PF03205.9 EXF83728.1 - 0.00076 19.1 1.3 0.84 9.3 0.1 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EXF83728.1 - 0.0008 18.8 0.3 0.36 10.2 0.0 3.3 4 0 0 4 4 3 1 AAA domain AAA_10 PF12846.2 EXF83728.1 - 0.0011 18.4 1.1 1.2 8.4 0.1 2.5 2 0 0 2 2 2 2 AAA-like domain Arch_ATPase PF01637.13 EXF83728.1 - 0.0019 17.9 0.1 0.64 9.6 0.0 2.6 2 0 0 2 2 2 1 Archaeal ATPase RNA_helicase PF00910.17 EXF83728.1 - 0.0021 18.2 0.2 4.3 7.5 0.0 3.2 3 0 0 3 3 3 0 RNA helicase AAA_17 PF13207.1 EXF83728.1 - 0.0022 18.7 0.5 0.29 11.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain DEAD PF00270.24 EXF83728.1 - 0.0046 16.4 0.5 2.2 7.7 0.0 3.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase ATP-synt_ab PF00006.20 EXF83728.1 - 0.0057 16.1 0.2 0.36 10.2 0.0 2.8 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.1 EXF83728.1 - 0.0068 15.9 3.9 0.69 9.4 0.2 3.0 3 0 0 3 3 2 1 P-loop containing region of AAA domain Septin PF00735.13 EXF83728.1 - 0.0084 15.1 0.2 4.5 6.2 0.0 2.6 2 0 0 2 2 2 0 Septin Dynamin_N PF00350.18 EXF83728.1 - 0.01 15.6 4.5 0.18 11.6 0.0 3.0 3 0 0 3 3 3 0 Dynamin family AIG1 PF04548.11 EXF83728.1 - 0.01 14.9 0.0 0.027 13.5 0.0 1.7 1 0 0 1 1 1 0 AIG1 family IstB_IS21 PF01695.12 EXF83728.1 - 0.011 15.1 1.6 2.2 7.6 0.0 3.5 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_5 PF07728.9 EXF83728.1 - 0.014 15.1 0.5 7 6.3 0.0 3.2 3 1 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EXF83728.1 - 0.021 14.7 0.5 3.8 7.4 0.0 3.4 4 0 0 4 4 3 0 AAA domain NACHT PF05729.7 EXF83728.1 - 0.022 14.4 0.9 6.7 6.3 0.0 2.7 2 0 0 2 2 2 0 NACHT domain PRK PF00485.13 EXF83728.1 - 0.028 13.9 1.0 0.24 10.9 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family FtsK_SpoIIIE PF01580.13 EXF83728.1 - 0.032 13.6 0.4 0.11 11.9 0.0 2.1 2 0 0 2 2 1 0 FtsK/SpoIIIE family AAA_30 PF13604.1 EXF83728.1 - 0.033 13.7 0.9 15 5.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 EXF83728.1 - 0.036 14.0 0.0 1.2 9.1 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EXF83728.1 - 0.081 12.0 0.0 13 4.8 0.0 2.7 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.1 EXF83728.1 - 0.09 12.3 0.0 0.71 9.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EXF83728.1 - 0.11 12.0 0.7 3.2 7.2 0.1 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_PrkA PF08298.6 EXF83728.1 - 0.12 11.0 0.5 0.72 8.4 0.0 2.1 2 0 0 2 2 2 0 PrkA AAA domain Pox_A32 PF04665.7 EXF83728.1 - 0.16 11.2 0.1 0.62 9.3 0.0 1.9 1 0 0 1 1 1 0 Poxvirus A32 protein UPF0079 PF02367.12 EXF83728.1 - 0.21 11.2 0.7 3.4 7.3 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Adeno_IVa2 PF02456.10 EXF83728.1 - 0.25 9.9 0.0 1.6 7.3 0.0 1.9 2 0 0 2 2 2 0 Adenovirus IVa2 protein ATP_bind_1 PF03029.12 EXF83728.1 - 0.85 9.1 5.6 0.51 9.8 0.0 2.7 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.10 EXF83728.1 - 1.9 8.1 5.4 1.1 8.9 0.0 3.1 4 0 0 4 4 3 0 NTPase AAA_18 PF13238.1 EXF83728.1 - 3.5 7.9 4.6 2.9 8.2 0.0 2.7 3 0 0 3 3 2 0 AAA domain BTV_NS2 PF04514.7 EXF83729.1 - 0.18 10.6 5.9 0.33 9.8 4.1 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 eIF3_subunit PF08597.5 EXF83729.1 - 0.42 10.1 8.4 0.71 9.3 5.9 1.3 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit YjeF_N PF03853.10 EXF83732.1 - 1.9e-33 115.4 0.0 2.3e-33 115.1 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus DUF4066 PF13278.1 EXF83733.1 - 1.2e-15 57.2 0.0 1.4e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EXF83733.1 - 8.7e-07 28.5 0.0 1.3e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 DJ-1/PfpI family DUF877 PF05943.7 EXF83733.1 - 0.033 12.6 0.0 0.045 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF877) DASH_Spc19 PF08287.6 EXF83734.1 - 1.1e-41 142.0 0.0 1.4e-41 141.6 0.0 1.2 1 0 0 1 1 1 1 Spc19 SlyX PF04102.7 EXF83734.1 - 0.011 16.0 0.4 0.17 12.2 0.0 2.6 3 0 0 3 3 3 0 SlyX Lzipper-MIP1 PF14389.1 EXF83734.1 - 0.092 12.8 4.9 0.91 9.6 2.4 2.6 3 0 0 3 3 3 0 Leucine-zipper of ternary complex factor MIP1 Med9 PF07544.8 EXF83734.1 - 2.7 7.7 5.0 28 4.5 0.8 2.6 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 SH3_1 PF00018.23 EXF83735.1 - 6.8e-10 38.1 0.3 2.7e-09 36.2 0.0 2.0 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EXF83735.1 - 2.5e-07 30.1 0.0 5e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EXF83735.1 - 1.1e-06 28.0 0.0 2.1e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF2417 PF10329.4 EXF83735.1 - 0.0004 19.8 2.1 0.00061 19.2 1.5 1.3 1 0 0 1 1 1 1 Region of unknown function (DUF2417) MARVEL PF01284.18 EXF83735.1 - 0.16 11.7 13.7 0.24 11.2 9.5 1.2 1 0 0 1 1 1 0 Membrane-associating domain TMEM220 PF15071.1 EXF83735.1 - 0.5 10.8 5.3 0.88 10.0 3.6 1.4 1 0 0 1 1 1 0 Transmembrane family 220, helix MpPF26 PF07666.6 EXF83735.1 - 6.2 6.7 7.8 1.7 8.5 0.9 2.1 1 1 1 2 2 2 0 M penetrans paralogue family 26 Mito_fiss_reg PF05308.6 EXF83736.1 - 0.95 8.7 6.4 2.1 7.6 4.4 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator Aa_trans PF01490.13 EXF83738.1 - 3.9e-91 305.5 19.1 3.9e-91 305.5 13.2 1.3 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EXF83738.1 - 9.7e-05 21.3 22.9 0.0002 20.3 15.9 1.5 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Ribosomal_S16 PF00886.14 EXF83739.1 - 3.1e-24 84.4 0.2 5.7e-24 83.6 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein S16 Methyltransf_23 PF13489.1 EXF83740.1 - 5.9e-25 87.8 0.0 9.2e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF83740.1 - 2e-13 50.8 0.0 2.4e-12 47.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF83740.1 - 2.2e-11 43.5 0.0 1.2e-10 41.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF83740.1 - 3.9e-10 40.0 0.0 9.9e-10 38.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF83740.1 - 4.2e-07 30.3 0.0 3.8e-06 27.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EXF83740.1 - 0.00026 21.0 0.0 0.00055 19.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EXF83740.1 - 0.0018 18.2 0.1 0.0097 15.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EXF83740.1 - 0.0023 17.2 0.0 0.0042 16.3 0.0 1.4 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain PrmA PF06325.8 EXF83740.1 - 0.0039 16.3 0.0 0.0062 15.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.1 EXF83740.1 - 0.0049 17.2 0.0 0.014 15.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF83740.1 - 0.0088 15.4 0.0 0.048 13.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_16 PF10294.4 EXF83740.1 - 0.026 13.9 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 EXF83740.1 - 0.034 13.2 0.0 14 4.6 0.0 2.9 2 1 1 3 3 3 0 ubiE/COQ5 methyltransferase family GPI-anchored PF10342.4 EXF83741.1 - 2.2e-15 56.9 0.8 2.2e-15 56.9 0.5 2.6 2 1 1 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family DUF4369 PF14289.1 EXF83741.1 - 0.015 15.2 1.3 0.026 14.5 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4369) DUF2807 PF10988.3 EXF83741.1 - 1 8.8 16.3 1.6 8.2 11.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2807) SH3_9 PF14604.1 EXF83742.1 - 3.7e-10 39.2 5.1 7.1e-07 28.7 0.4 2.6 2 0 0 2 2 2 2 Variant SH3 domain SH3_2 PF07653.12 EXF83742.1 - 0.00011 21.6 4.4 0.00099 18.5 0.2 2.5 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EXF83742.1 - 0.78 9.1 5.5 0.14 11.5 0.5 2.2 2 0 0 2 2 2 0 SH3 domain MFS_1 PF07690.11 EXF83743.1 - 8.4e-39 133.2 34.2 8.4e-39 133.2 23.7 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily NmrA PF05368.8 EXF83744.1 - 3.4e-26 91.9 0.0 4.3e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF83744.1 - 2.6e-08 34.0 0.0 3.9e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EXF83744.1 - 6.6e-06 26.4 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EXF83744.1 - 9.4e-06 25.5 0.1 2e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Saccharop_dh PF03435.13 EXF83744.1 - 0.0008 18.4 0.1 0.0012 17.8 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_4 PF07993.7 EXF83744.1 - 0.015 14.2 0.0 0.021 13.7 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein DXP_reductoisom PF02670.11 EXF83744.1 - 0.026 15.0 0.1 0.055 13.9 0.0 1.6 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Glyco_hydro_11 PF00457.12 EXF83745.1 - 2.8e-57 193.0 12.8 3.3e-57 192.7 8.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 11 NAD_binding_10 PF13460.1 EXF83746.1 - 3.1e-10 40.3 0.0 4.5e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF83746.1 - 2.3e-09 37.0 0.0 4.2e-09 36.1 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EXF83746.1 - 0.0074 15.5 0.3 1.6 7.9 0.4 2.6 2 1 0 2 2 2 2 NmrA-like family Pyr_redox_2 PF07992.9 EXF83746.1 - 0.023 14.5 0.0 0.69 9.7 0.1 2.3 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 EXF83747.1 - 1.5e-36 125.8 30.8 1.5e-36 125.8 21.4 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily COX14 PF14880.1 EXF83747.1 - 0.17 11.4 0.0 0.17 11.4 0.0 3.1 2 1 1 3 3 3 0 Cytochrome oxidase c assembly Aldedh PF00171.17 EXF83748.1 - 3.8e-76 256.2 0.0 4.3e-76 256.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family FAD_binding_3 PF01494.14 EXF83749.1 - 7.1e-51 173.3 0.0 1.3e-50 172.4 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF83749.1 - 3.1e-11 42.7 0.5 3e-07 29.7 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase GST_C_3 PF14497.1 EXF83749.1 - 1.2e-10 41.7 0.0 2.4e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FAD_binding_2 PF00890.19 EXF83749.1 - 4.9e-09 35.5 0.1 1.1e-05 24.4 0.2 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.2 EXF83749.1 - 1.7e-06 27.3 0.0 4e-06 26.1 0.0 1.5 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF83749.1 - 2.2e-06 27.7 0.0 5.3e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF83749.1 - 1.1e-05 25.7 0.9 0.0041 17.4 0.0 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF83749.1 - 3.1e-05 23.9 0.1 8.8e-05 22.4 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EXF83749.1 - 3.9e-05 22.2 0.1 6e-05 21.6 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.12 EXF83749.1 - 0.00012 21.3 0.0 0.00025 20.2 0.0 1.5 1 0 0 1 1 1 1 Thi4 family ApbA PF02558.11 EXF83749.1 - 0.00092 18.6 0.1 0.0018 17.7 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 EXF83749.1 - 0.00095 18.1 0.1 0.0015 17.4 0.1 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EXF83749.1 - 0.0018 18.3 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF83749.1 - 0.0027 16.6 0.2 0.0043 16.0 0.1 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 EXF83749.1 - 0.0039 17.4 0.0 0.0087 16.3 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding GST_C_2 PF13410.1 EXF83749.1 - 0.0049 16.7 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ThiF PF00899.16 EXF83749.1 - 0.015 15.1 0.0 0.029 14.2 0.0 1.4 1 0 0 1 1 1 0 ThiF family GST_N_3 PF13417.1 EXF83749.1 - 0.023 14.9 0.1 0.09 13.0 0.1 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain UDPG_MGDP_dh_N PF03721.9 EXF83749.1 - 0.026 13.8 0.1 0.047 13.0 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EXF83749.1 - 0.036 13.7 0.1 0.075 12.6 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.9 EXF83749.1 - 0.045 12.3 0.1 0.08 11.5 0.1 1.4 1 0 0 1 1 1 0 Tryptophan halogenase Beta-lactamase PF00144.19 EXF83750.1 - 9.1e-19 67.6 0.1 1.4e-18 67.0 0.1 1.1 1 0 0 1 1 1 1 Beta-lactamase NACHT PF05729.7 EXF83752.1 - 0.21 11.2 0.7 1.8 8.2 0.2 2.5 2 1 0 2 2 2 0 NACHT domain TP_methylase PF00590.15 EXF83753.1 - 3.3e-44 151.1 0.2 6.1e-44 150.2 0.1 1.5 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases NAD_binding_7 PF13241.1 EXF83753.1 - 1.3e-13 51.0 0.0 2.8e-13 50.0 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EXF83753.1 - 1.2e-10 40.4 0.1 1.8e-08 33.5 0.0 2.4 2 0 0 2 2 2 2 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EXF83753.1 - 2.3e-05 23.2 0.0 4.9e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central Rsm22 PF09243.5 EXF83754.1 - 8.3e-29 100.4 0.0 2.8e-28 98.7 0.0 1.8 1 1 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.1 EXF83754.1 - 0.00018 21.3 0.0 0.00045 19.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF83754.1 - 0.0033 17.0 0.1 0.26 10.8 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF83754.1 - 0.009 16.4 0.0 0.044 14.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF83754.1 - 0.016 15.8 2.5 0.14 12.7 0.1 3.3 3 1 0 3 3 3 0 Methyltransferase domain V_ATPase_I PF01496.14 EXF83754.1 - 8.4 4.1 8.7 12 3.5 6.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ank_2 PF12796.2 EXF83755.1 - 5.4e-101 331.1 21.6 2.2e-20 72.7 0.1 6.3 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EXF83755.1 - 8.7e-74 239.8 3.1 8.5e-08 31.6 0.0 12.6 12 0 0 12 12 12 12 Ankyrin repeat Ank_5 PF13857.1 EXF83755.1 - 6.7e-59 194.5 7.5 2.4e-10 40.2 0.0 9.4 4 3 5 9 9 9 9 Ankyrin repeats (many copies) Ank_4 PF13637.1 EXF83755.1 - 3.2e-56 186.7 8.8 7e-10 39.1 0.0 8.2 5 2 2 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF83755.1 - 7.3e-51 165.0 8.5 2.9e-05 23.8 0.0 12.8 13 0 0 13 13 13 9 Ankyrin repeat HET PF06985.6 EXF83755.1 - 5.1e-20 72.0 14.1 4.6e-19 68.9 2.3 3.4 2 2 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Reo_sigmaC PF04582.7 EXF83755.1 - 1.9 7.5 6.9 4.8 6.2 4.8 1.6 1 0 0 1 1 1 0 Reovirus sigma C capsid protein GAS PF13851.1 EXF83755.1 - 5.2 6.2 20.1 4.6 6.3 10.2 2.4 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding V_ATPase_I PF01496.14 EXF83755.1 - 8.1 4.1 8.7 15 3.3 6.0 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EXF83755.1 - 9.5 5.7 15.4 17 4.9 10.7 1.4 1 0 0 1 1 1 0 IncA protein Thioredoxin PF00085.15 EXF83756.1 - 6.8e-26 89.9 0.0 9.8e-26 89.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EXF83756.1 - 2.9e-08 33.7 0.0 6.1e-07 29.4 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.1 EXF83756.1 - 1.6e-07 31.4 0.2 6.2e-07 29.6 0.1 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EXF83756.1 - 0.00037 20.1 0.0 0.0007 19.2 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EXF83756.1 - 0.00046 19.7 0.0 0.00069 19.1 0.0 1.3 1 0 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.1 EXF83756.1 - 0.0015 18.0 0.0 0.0022 17.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_4 PF13462.1 EXF83756.1 - 0.0095 15.9 0.4 1 9.3 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_7 PF13899.1 EXF83756.1 - 0.015 15.2 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like HyaE PF07449.6 EXF83756.1 - 0.14 12.0 0.0 0.47 10.3 0.0 1.7 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Methyltrn_RNA_3 PF02598.12 EXF83757.1 - 5.8e-80 268.7 0.0 6.6e-80 268.5 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase Pectate_lyase_3 PF12708.2 EXF83758.1 - 4.6e-73 246.0 15.0 4e-62 210.2 2.4 3.3 3 0 0 3 3 3 2 Pectate lyase superfamily protein End_N_terminal PF12218.3 EXF83758.1 - 3.8e-06 26.2 0.7 0.047 13.1 0.1 2.6 2 0 0 2 2 2 2 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.1 EXF83758.1 - 0.0043 16.8 4.1 0.0043 16.8 2.8 3.0 2 1 0 2 2 2 1 Right handed beta helix region Radical_SAM PF04055.16 EXF83759.1 - 2.9e-12 47.0 0.0 5.2e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Spore_GerAC PF05504.6 EXF83759.1 - 0.0054 16.5 0.0 0.012 15.3 0.0 1.5 1 1 0 1 1 1 1 Spore germination B3/ GerAC like, C-terminal Mucin PF01456.12 EXF83760.1 - 1.4 8.6 21.9 2.1 8.1 15.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein F-box-like PF12937.2 EXF83761.1 - 0.016 14.9 0.3 0.039 13.6 0.2 1.7 1 0 0 1 1 1 0 F-box-like Zn_clus PF00172.13 EXF83762.1 - 6e-07 29.2 9.7 1.7e-06 27.8 6.7 1.8 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.1 EXF83763.1 - 3.6e-10 40.1 0.2 1.5e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EXF83763.1 - 7.1e-10 38.5 0.0 9.6e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EXF83763.1 - 0.0074 15.2 0.0 0.026 13.4 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.19 EXF83763.1 - 0.0083 16.4 0.0 0.018 15.3 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EXF83763.1 - 0.024 14.0 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EXF83763.1 - 0.031 14.3 0.0 0.06 13.4 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Ldh_1_N PF00056.18 EXF83763.1 - 0.038 13.8 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain DapB_N PF01113.15 EXF83763.1 - 0.086 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 EXF83763.1 - 0.15 12.5 0.9 0.33 11.4 0.1 2.0 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 EXF83764.1 - 3.6e-15 56.2 0.0 1.6e-14 54.1 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase Epimerase PF01370.16 EXF83764.1 - 0.0061 16.0 0.0 0.033 13.6 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EXF83764.1 - 0.034 13.8 0.0 0.078 12.6 0.0 1.5 1 0 0 1 1 1 0 KR domain PIF1 PF05970.9 EXF83765.1 - 2.5e-17 62.9 1.4 1.5e-10 40.5 0.0 3.1 2 1 1 3 3 3 3 PIF1-like helicase Herpes_Helicase PF02689.9 EXF83765.1 - 4.4e-07 28.0 0.0 7.1e-07 27.3 0.0 1.2 1 0 0 1 1 1 1 Helicase UvrD_C_2 PF13538.1 EXF83765.1 - 4.1e-05 23.6 0.0 0.00011 22.3 0.0 1.8 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain PIF1 PF05970.9 EXF83766.1 - 6.4e-11 41.8 0.1 8.1e-11 41.4 0.1 1.1 1 0 0 1 1 1 1 PIF1-like helicase AAA_30 PF13604.1 EXF83766.1 - 1.2e-06 28.2 0.0 1.5e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EXF83766.1 - 3.1e-05 23.6 0.0 4.4e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Part of AAA domain AAA_29 PF13555.1 EXF83766.1 - 5.9e-05 22.5 0.0 0.00012 21.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Mg_chelatase PF01078.16 EXF83766.1 - 6.3e-05 22.2 0.1 9.6e-05 21.6 0.1 1.2 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EXF83766.1 - 0.00069 19.6 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 EXF83766.1 - 0.00086 18.3 0.0 0.0011 17.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Pox_A32 PF04665.7 EXF83766.1 - 0.0013 18.0 0.0 0.0017 17.7 0.0 1.1 1 0 0 1 1 1 1 Poxvirus A32 protein ABC_tran PF00005.22 EXF83766.1 - 0.0028 17.9 0.0 0.0041 17.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ArgK PF03308.11 EXF83766.1 - 0.011 14.5 0.0 0.015 14.1 0.0 1.1 1 0 0 1 1 1 0 ArgK protein DUF258 PF03193.11 EXF83766.1 - 0.021 14.0 0.0 0.029 13.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EXF83766.1 - 0.022 14.4 0.0 0.03 14.0 0.0 1.1 1 0 0 1 1 1 0 Archaeal ATPase NB-ARC PF00931.17 EXF83766.1 - 0.024 13.5 0.1 0.032 13.0 0.1 1.1 1 0 0 1 1 1 0 NB-ARC domain AAA_32 PF13654.1 EXF83766.1 - 0.042 12.5 0.1 0.058 12.0 0.0 1.1 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EXF83766.1 - 0.043 13.0 0.0 0.06 12.5 0.0 1.1 1 0 0 1 1 1 0 PhoH-like protein T2SE PF00437.15 EXF83766.1 - 0.047 12.5 0.0 0.053 12.4 0.0 1.1 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 EXF83766.1 - 0.063 13.4 0.1 0.083 13.0 0.0 1.2 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EXF83766.1 - 0.074 13.2 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 RNA helicase Sigma54_activat PF00158.21 EXF83766.1 - 0.079 12.4 0.1 0.09 12.2 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_10 PF12846.2 EXF83766.1 - 0.087 12.2 0.1 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_28 PF13521.1 EXF83766.1 - 0.091 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EXF83766.1 - 0.098 12.7 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Viral_helicase1 PF01443.13 EXF83766.1 - 0.11 12.0 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase G-alpha PF00503.15 EXF83766.1 - 0.13 10.9 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 G-protein alpha subunit FtsK_SpoIIIE PF01580.13 EXF83766.1 - 0.13 11.6 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Rad17 PF03215.10 EXF83766.1 - 0.14 10.8 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Zeta_toxin PF06414.7 EXF83766.1 - 0.16 11.0 0.0 0.24 10.4 0.0 1.1 1 0 0 1 1 1 0 Zeta toxin FMN_dh PF01070.13 EXF83767.1 - 6.3e-112 373.9 0.1 1.6e-111 372.6 0.1 1.6 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EXF83767.1 - 3.8e-19 68.2 0.0 9.5e-19 66.9 0.0 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EXF83767.1 - 2.8e-07 29.7 0.1 4.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EXF83767.1 - 6.7e-05 21.9 1.2 0.00042 19.3 0.1 2.1 1 1 1 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EXF83767.1 - 0.00018 20.8 0.6 0.00028 20.1 0.4 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 EXF83767.1 - 0.00037 19.6 0.0 0.14 11.1 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_syn_central PF04898.9 EXF83767.1 - 0.029 13.6 0.0 0.042 13.1 0.0 1.3 1 0 0 1 1 1 0 Glutamate synthase central domain His_biosynth PF00977.16 EXF83767.1 - 0.035 13.3 0.1 0.47 9.6 0.0 2.5 3 0 0 3 3 3 0 Histidine biosynthesis protein DHO_dh PF01180.16 EXF83767.1 - 0.048 12.6 0.1 0.14 11.1 0.0 1.7 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase MFS_1 PF07690.11 EXF83768.1 - 8.5e-35 120.0 26.3 8.5e-35 120.0 18.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF3390 PF11870.3 EXF83768.1 - 0.0085 15.9 0.0 0.017 15.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3390) Glyco_hydro_61 PF03443.9 EXF83769.1 - 1.8e-41 142.3 0.0 2.5e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Glyco_hydro_30 PF02055.11 EXF83770.1 - 3.7e-17 61.6 2.3 9.6e-10 37.2 0.5 2.6 2 1 0 2 2 2 2 O-Glycosyl hydrolase family 30 Glyco_hydr_30_2 PF14587.1 EXF83770.1 - 1.2e-16 60.6 1.6 2.5e-16 59.6 0.0 2.2 2 1 0 2 2 2 1 O-Glycosyl hydrolase family 30 Alpha-L-AF_C PF06964.7 EXF83770.1 - 0.0004 20.2 0.2 0.00072 19.3 0.2 1.4 1 0 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminus PCI PF01399.22 EXF83772.1 - 9.8e-21 74.0 0.1 3e-20 72.5 0.1 1.8 1 0 0 1 1 1 1 PCI domain PCI_Csn8 PF10075.4 EXF83772.1 - 0.027 14.2 0.2 0.085 12.6 0.0 1.9 2 0 0 2 2 2 0 COP9 signalosome, subunit CSN8 FSH1 PF03959.8 EXF83773.1 - 8.3e-60 201.8 0.0 1e-59 201.5 0.0 1.1 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EXF83773.1 - 3.4e-08 33.6 2.1 7.3e-05 22.7 1.4 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF83773.1 - 3.9e-07 29.9 0.1 6.2e-07 29.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF83773.1 - 0.003 17.1 0.2 0.26 10.8 0.2 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase_phd PF10503.4 EXF83773.1 - 0.0035 16.6 0.0 0.17 11.1 0.0 2.3 2 0 0 2 2 2 1 Esterase PHB depolymerase DLH PF01738.13 EXF83773.1 - 0.0055 16.0 0.0 0.78 8.9 0.0 2.2 2 0 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EXF83773.1 - 0.034 13.5 0.1 18 4.6 0.1 3.0 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase Chorion_S16 PF05836.7 EXF83773.1 - 0.052 13.4 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Chorion protein S16 ATP-synt_J PF04911.7 EXF83774.1 - 1.9e-26 91.2 0.5 2.1e-26 91.1 0.4 1.0 1 0 0 1 1 1 1 ATP synthase j chain NIPSNAP PF07978.8 EXF83775.1 - 6e-39 132.1 0.4 1.8e-28 98.4 0.1 2.5 2 0 0 2 2 2 2 NIPSNAP ASD2 PF08687.6 EXF83775.1 - 0.011 15.1 1.9 0.02 14.2 1.3 1.4 1 0 0 1 1 1 0 Apx/Shroom domain ASD2 Pex26 PF07163.7 EXF83775.1 - 0.26 10.1 2.6 0.41 9.5 1.8 1.2 1 0 0 1 1 1 0 Pex26 protein Rogdi_lz PF10259.4 EXF83776.1 - 1.5e-67 227.5 0.0 1.8e-67 227.3 0.0 1.0 1 0 0 1 1 1 1 Rogdi leucine zipper containing protein Rpp20 PF12328.3 EXF83777.1 - 5.3e-29 100.7 0.1 8.8e-29 100.0 0.0 1.4 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P Alba PF01918.16 EXF83777.1 - 1.4e-18 66.1 0.0 2.2e-18 65.6 0.0 1.3 1 0 0 1 1 1 1 Alba KAR9 PF08580.5 EXF83777.1 - 0.21 9.8 4.6 0.29 9.3 3.2 1.2 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Peptidase_C69 PF03577.10 EXF83779.1 - 3.5e-26 92.0 0.1 5e-26 91.4 0.1 1.2 1 0 0 1 1 1 1 Peptidase family C69 Acyl_transf_3 PF01757.17 EXF83780.1 - 2.5e-32 112.0 30.9 1.4e-31 109.6 21.4 2.0 1 1 0 1 1 1 1 Acyltransferase family DUF418 PF04235.7 EXF83780.1 - 0.00031 20.4 6.0 0.00031 20.4 4.2 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF418) Ifi-6-16 PF06140.8 EXF83782.1 - 0.00024 20.8 27.0 0.00087 19.0 18.3 2.1 1 1 1 2 2 2 1 Interferon-induced 6-16 family DUF2205 PF10224.4 EXF83783.1 - 3.1e-05 23.4 2.9 5.3e-05 22.7 2.0 1.3 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) DUF972 PF06156.8 EXF83783.1 - 0.0049 17.1 1.6 0.0072 16.6 1.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF972) Prominin PF05478.6 EXF83783.1 - 0.0061 14.1 0.3 0.0072 13.9 0.2 1.0 1 0 0 1 1 1 1 Prominin Herpes_UL6 PF01763.11 EXF83783.1 - 0.0081 14.3 0.3 0.0089 14.2 0.2 1.1 1 0 0 1 1 1 1 Herpesvirus UL6 like FlgN PF05130.7 EXF83783.1 - 0.012 15.8 1.4 0.015 15.5 1.0 1.2 1 0 0 1 1 1 0 FlgN protein DUF1875 PF08961.5 EXF83783.1 - 0.014 14.6 0.2 0.017 14.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1875) CENP-Q PF13094.1 EXF83783.1 - 0.015 15.3 3.5 0.019 15.0 2.4 1.2 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF812 PF05667.6 EXF83783.1 - 0.019 13.4 3.4 0.024 13.1 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Spc7 PF08317.6 EXF83783.1 - 0.028 13.0 1.5 0.036 12.7 1.0 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4638 PF15472.1 EXF83783.1 - 0.067 12.7 0.1 0.085 12.4 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) FH2 PF02181.18 EXF83783.1 - 0.07 12.0 0.3 0.082 11.7 0.2 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain YlbD_coat PF14071.1 EXF83783.1 - 0.079 13.0 0.4 0.11 12.5 0.3 1.3 1 0 0 1 1 1 0 Putative coat protein TSC22 PF01166.13 EXF83783.1 - 0.083 12.8 0.8 0.16 11.9 0.6 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family DivIC PF04977.10 EXF83783.1 - 0.086 12.3 2.4 0.16 11.4 1.6 1.5 1 0 0 1 1 1 0 Septum formation initiator BLOC1_2 PF10046.4 EXF83783.1 - 0.1 12.7 0.9 0.17 12.0 0.6 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-H PF05837.7 EXF83783.1 - 0.11 12.7 1.6 0.18 11.9 0.9 1.5 1 1 0 1 1 1 0 Centromere protein H (CENP-H) Atg14 PF10186.4 EXF83783.1 - 0.12 11.3 1.3 0.14 11.0 0.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF904 PF06005.7 EXF83783.1 - 0.12 12.6 4.9 0.24 11.7 3.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF904) P4Ha_N PF08336.6 EXF83783.1 - 0.14 11.9 1.1 0.2 11.4 0.8 1.2 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region IncA PF04156.9 EXF83783.1 - 0.16 11.5 3.3 0.21 11.1 2.3 1.2 1 0 0 1 1 1 0 IncA protein DUF4201 PF13870.1 EXF83783.1 - 0.16 11.4 3.4 0.24 10.8 2.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) SseC PF04888.7 EXF83783.1 - 0.32 10.3 1.3 0.46 9.7 0.9 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family NPV_P10 PF05531.7 EXF83783.1 - 0.32 11.2 3.6 0.63 10.3 2.5 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein bZIP_2 PF07716.10 EXF83783.1 - 0.42 10.4 3.0 0.42 10.4 1.1 1.7 1 1 1 2 2 2 0 Basic region leucine zipper Kelch_5 PF13854.1 EXF83784.1 - 4.2e-13 48.9 5.3 1.6e-05 24.6 0.0 5.8 7 0 0 7 7 7 3 Kelch motif Kelch_4 PF13418.1 EXF83784.1 - 4.6e-06 26.2 10.3 0.23 11.2 0.1 6.0 7 1 0 7 7 7 3 Galactose oxidase, central domain SKG6 PF08693.5 EXF83784.1 - 2.5e-05 23.4 0.1 5.6e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain Kelch_2 PF07646.10 EXF83784.1 - 0.00021 20.8 1.5 1.8 8.4 0.0 4.7 4 0 0 4 4 4 2 Kelch motif Syndecan PF01034.15 EXF83784.1 - 0.009 15.6 0.4 0.019 14.5 0.2 1.5 1 0 0 1 1 1 1 Syndecan domain Herpes_gE PF02480.11 EXF83784.1 - 0.015 13.6 0.0 0.022 13.0 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Kelch_1 PF01344.20 EXF83784.1 - 0.08 12.5 5.2 9.2 5.8 0.1 4.1 4 0 0 4 4 4 0 Kelch motif DUF1191 PF06697.7 EXF83784.1 - 0.1 11.4 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) DUF1399 PF07173.7 EXF83785.1 - 1e-22 80.9 0.9 3.1e-18 66.3 0.0 3.1 2 2 1 3 3 3 2 Protein of unknown function (DUF1399) Serglycin PF04360.7 EXF83785.1 - 0.13 12.0 0.1 0.21 11.3 0.1 1.3 1 0 0 1 1 1 0 Serglycin P12 PF12669.2 EXF83785.1 - 0.33 11.1 10.4 0.55 10.4 7.2 1.4 1 0 0 1 1 1 0 Virus attachment protein p12 family Peroxidase_2 PF01328.12 EXF83786.1 - 5.9e-42 143.4 0.2 6.9e-42 143.2 0.1 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 WD40 PF00400.27 EXF83788.1 - 8.8e-30 101.5 8.1 4.6e-06 26.2 0.0 8.4 8 0 0 8 8 8 8 WD domain, G-beta repeat SKG6 PF08693.5 EXF83789.1 - 1.3e-08 33.9 6.8 2.7e-08 32.9 4.7 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain RCR PF12273.3 EXF83789.1 - 0.0078 16.7 12.4 0.03 14.8 8.6 1.9 1 1 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red DUF4448 PF14610.1 EXF83789.1 - 0.017 14.6 0.0 0.025 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Rifin_STEVOR PF02009.11 EXF83789.1 - 0.027 14.0 0.0 0.04 13.5 0.0 1.2 1 0 0 1 1 1 0 Rifin/stevor family DUF2029 PF09594.5 EXF83789.1 - 0.062 12.8 10.9 0.096 12.1 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2029) CorA PF01544.13 EXF83790.1 - 9.5e-10 37.9 0.0 2.1e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein ADH_zinc_N_2 PF13602.1 EXF83791.1 - 7.6e-07 30.0 0.1 1.6e-06 29.0 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EXF83791.1 - 1.5e-05 24.5 0.0 2.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Lon_C PF05362.8 EXF83791.1 - 0.065 12.5 0.0 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 Lon protease (S16) C-terminal proteolytic domain Peptidase_S10 PF00450.17 EXF83792.1 - 6.9e-91 305.4 0.0 8.5e-91 305.1 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EXF83792.1 - 2.3e-06 27.6 0.0 6.2e-05 22.9 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF83792.1 - 0.076 12.7 0.0 0.18 11.5 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family GDC-P PF02347.11 EXF83793.1 - 2.6e-170 566.7 0.0 4.3e-159 529.8 0.0 3.0 2 1 0 2 2 2 2 Glycine cleavage system P-protein Aminotran_5 PF00266.14 EXF83793.1 - 9.8e-11 40.9 0.2 0.00023 20.0 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Beta_elim_lyase PF01212.16 EXF83793.1 - 5e-06 25.8 0.0 8.1e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.15 EXF83793.1 - 0.0058 14.9 0.0 0.013 13.8 0.0 1.5 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme B12-binding PF02310.14 EXF83793.1 - 0.013 15.3 0.8 0.11 12.3 0.0 2.9 3 0 0 3 3 3 0 B12 binding domain Tom5 PF10642.4 EXF83794.1 - 3.9e-14 52.0 0.6 6.6e-14 51.2 0.4 1.4 1 0 0 1 1 1 1 Mitochondrial import receptor subunit or translocase Nup54 PF13874.1 EXF83795.1 - 1.7e-44 150.9 0.9 6.7e-44 148.9 0.0 2.0 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 DivIVA PF05103.8 EXF83795.1 - 0.016 15.2 1.0 0.016 15.2 0.7 1.7 2 0 0 2 2 2 0 DivIVA protein YliH PF10799.3 EXF83795.1 - 0.048 13.3 0.3 0.1 12.2 0.2 1.7 1 1 0 1 1 1 0 Biofilm formation protein (YliH/bssR) V-SNARE_C PF12352.3 EXF83795.1 - 0.057 13.4 0.4 1.2 9.3 0.1 2.3 2 0 0 2 2 2 0 Snare region anchored in the vesicle membrane C-terminus Tup_N PF08581.5 EXF83795.1 - 0.074 13.2 2.5 0.22 11.7 1.8 1.8 1 0 0 1 1 1 0 Tup N-terminal DUF948 PF06103.6 EXF83795.1 - 0.075 12.9 1.0 0.64 9.9 0.2 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Use1 PF09753.4 EXF83795.1 - 0.076 12.4 1.4 0.11 11.9 0.2 1.8 2 0 0 2 2 2 0 Membrane fusion protein Use1 FlaC_arch PF05377.6 EXF83795.1 - 0.079 12.8 3.2 0.22 11.4 0.4 2.7 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) HalX PF08663.5 EXF83795.1 - 0.13 12.2 6.8 0.57 10.1 0.5 3.2 3 0 0 3 3 3 0 HalX domain Transposase_22 PF02994.9 EXF83795.1 - 0.14 10.6 6.6 0.16 10.4 2.2 1.9 1 1 1 2 2 2 0 L1 transposable element XhlA PF10779.4 EXF83795.1 - 0.2 11.5 1.1 1.6 8.6 0.2 2.3 2 0 0 2 2 2 0 Haemolysin XhlA FUSC PF04632.7 EXF83795.1 - 0.27 9.6 3.5 0.32 9.3 2.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Syntaxin-6_N PF09177.6 EXF83795.1 - 0.35 11.3 3.7 0.49 10.8 0.5 2.4 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF2353 PF09789.4 EXF83795.1 - 0.48 9.6 6.8 2.3 7.3 4.7 1.8 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Uds1 PF15456.1 EXF83795.1 - 0.82 9.6 8.0 37 4.3 5.6 2.5 1 1 0 1 1 1 0 Up-regulated During Septation Prefoldin_2 PF01920.15 EXF83795.1 - 2.1 8.1 8.7 1.3 8.7 3.5 2.4 2 1 0 2 2 2 0 Prefoldin subunit Hemerythrin PF01814.18 EXF83795.1 - 3 7.9 7.2 7.8 6.6 4.8 1.8 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain CHCH PF06747.8 EXF83796.1 - 5.3e-07 29.4 13.0 1.9e-05 24.4 2.2 2.7 3 0 0 3 3 3 2 CHCH domain Cmc1 PF08583.5 EXF83796.1 - 0.0032 17.1 11.0 0.071 12.8 0.4 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.4 EXF83796.1 - 0.16 12.0 8.7 1.1 9.3 5.1 2.5 1 1 1 2 2 2 0 Cytochrome c oxidase assembly protein PET191 GCK PF07802.6 EXF83796.1 - 0.2 11.8 4.5 0.15 12.2 0.5 2.2 1 1 0 2 2 2 0 GCK domain CAP PF00188.21 EXF83797.1 - 2.4e-23 82.9 3.5 3.1e-23 82.5 2.4 1.2 1 0 0 1 1 1 1 Cysteine-rich secretory protein family IER PF05760.7 EXF83797.1 - 0.4 10.5 14.5 0.73 9.7 10.0 1.4 1 1 0 1 1 1 0 Immediate early response protein (IER) SSF PF00474.12 EXF83798.1 - 1.7e-24 86.1 29.7 2.6e-24 85.6 20.6 1.3 1 0 0 1 1 1 1 Sodium:solute symporter family Thioredox_DsbH PF03190.10 EXF83799.1 - 1.1e-56 191.0 0.0 1.8e-56 190.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 EXF83799.1 - 0.0014 18.5 0.0 0.0037 17.2 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like GlcNAc_2-epim PF07221.6 EXF83799.1 - 0.0046 16.0 0.2 0.0085 15.1 0.1 1.3 1 0 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) TRAM_LAG1_CLN8 PF03798.11 EXF83800.1 - 3e-44 150.9 17.7 3e-44 150.9 12.3 1.8 2 0 0 2 2 2 1 TLC domain TRAM1 PF08390.6 EXF83800.1 - 1.4e-19 69.3 0.5 3.5e-19 68.0 0.0 2.0 2 0 0 2 2 2 1 TRAM1-like protein Nucleos_tra2_N PF01773.15 EXF83800.1 - 0.34 11.2 4.9 13 6.1 0.1 2.5 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter N-terminus Bax1-I PF01027.15 EXF83801.1 - 1e-48 165.7 29.0 1.2e-48 165.4 20.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Spore_YhaL PF14147.1 EXF83801.1 - 0.43 10.0 0.1 0.43 10.0 0.1 2.4 3 0 0 3 3 3 0 Sporulation protein YhaL Septin PF00735.13 EXF83802.1 - 5.6e-106 353.6 0.0 1.3e-105 352.4 0.0 1.5 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EXF83802.1 - 0.0004 20.3 0.0 0.00075 19.4 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EXF83802.1 - 0.007 16.2 5.8 0.8 9.5 0.0 3.0 2 1 1 3 3 3 2 Dynamin family DUF258 PF03193.11 EXF83802.1 - 0.012 14.8 0.5 0.051 12.7 0.4 1.9 1 1 0 1 1 1 0 Protein of unknown function, DUF258 IIGP PF05049.8 EXF83802.1 - 0.023 13.5 0.0 0.042 12.6 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) Miro PF08477.8 EXF83802.1 - 0.024 15.1 0.0 0.071 13.6 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein AAA_22 PF13401.1 EXF83802.1 - 0.1 12.7 0.0 0.35 11.0 0.0 2.0 1 0 0 1 1 1 0 AAA domain GLE1 PF07817.8 EXF83802.1 - 0.15 10.9 0.5 0.24 10.2 0.3 1.2 1 0 0 1 1 1 0 GLE1-like protein FMN_bind PF04205.9 EXF83802.1 - 0.19 11.9 0.6 0.7 10.0 0.0 2.1 2 0 0 2 2 2 0 FMN-binding domain AAA_17 PF13207.1 EXF83802.1 - 0.26 12.1 4.7 0.55 11.0 0.2 2.9 2 2 0 2 2 2 0 AAA domain DUF3653 PF12375.3 EXF83802.1 - 0.56 10.4 3.2 15 5.8 1.3 2.9 2 1 0 2 2 2 0 Phage protein FtsK_SpoIIIE PF01580.13 EXF83802.1 - 3.1 7.2 5.8 0.31 10.4 0.2 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family WD40 PF00400.27 EXF83803.1 - 4.1e-08 32.8 0.9 0.0084 15.9 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat IKI3 PF04762.7 EXF83803.1 - 0.054 11.2 0.0 0.073 10.8 0.0 1.2 1 0 0 1 1 1 0 IKI3 family RRM_1 PF00076.17 EXF83804.1 - 9.9e-15 53.9 0.0 8.8e-14 50.8 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF83804.1 - 7.9e-08 32.1 0.0 2e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF83804.1 - 0.0064 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DLIC PF05783.6 EXF83805.1 - 6e-29 101.0 0.1 6e-27 94.4 0.0 2.7 2 2 0 2 2 2 2 Dynein light intermediate chain (DLIC) Cu_amine_oxid PF01179.15 EXF83807.1 - 1.4e-142 475.2 0.0 2e-142 474.7 0.0 1.2 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EXF83807.1 - 1e-06 28.7 0.0 3.2e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EXF83807.1 - 8.2e-05 22.5 0.0 0.00017 21.5 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Gly_transf_sug PF04488.10 EXF83808.1 - 1.7e-13 50.8 0.0 4.1e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif AMP-binding PF00501.23 EXF83809.1 - 5.6e-90 301.7 0.1 6.7e-90 301.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EXF83809.1 - 1e-16 61.6 0.0 3e-16 60.1 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HTH_15 PF12324.3 EXF83809.1 - 0.029 14.0 0.0 2.9 7.5 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase QRPTase_C PF01729.14 EXF83810.1 - 2e-54 183.6 0.3 2e-54 183.6 0.2 1.5 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EXF83810.1 - 3.5e-20 71.5 0.0 7.8e-20 70.5 0.0 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain PRAI PF00697.17 EXF83810.1 - 9.2e-05 22.0 0.3 0.0021 17.6 0.1 2.2 2 0 0 2 2 2 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase zf-C2H2_4 PF13894.1 EXF83810.1 - 0.00031 20.8 10.8 0.012 15.8 0.5 3.2 3 0 0 3 3 3 2 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EXF83810.1 - 0.078 13.1 2.4 0.14 12.3 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding IGPS PF00218.16 EXF83810.1 - 0.11 11.5 0.2 0.2 10.6 0.1 1.4 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase PLDc_2 PF13091.1 EXF83812.1 - 3.1e-07 30.1 0.0 0.004 16.9 0.0 2.9 4 0 0 4 4 4 2 PLD-like domain Fungal_trans PF04082.13 EXF83813.1 - 1.3e-14 53.7 0.4 2.4e-14 52.8 0.3 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF83813.1 - 6.4e-08 32.3 15.4 1.1e-07 31.6 10.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ABC2_membrane PF01061.19 EXF83814.1 - 7.8e-84 280.0 47.4 7.6e-46 155.9 14.7 2.5 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 EXF83814.1 - 5.8e-46 156.1 0.1 1.2e-22 80.6 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EXF83814.1 - 3.2e-26 90.9 0.3 2.3e-22 78.5 0.0 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 EXF83814.1 - 1.5e-10 40.6 34.2 3.4e-09 36.1 9.2 3.1 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_16 PF13191.1 EXF83814.1 - 6.1e-06 26.3 0.1 0.0048 16.8 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain SMC_N PF02463.14 EXF83814.1 - 4.5e-05 22.7 0.2 0.27 10.4 0.0 3.3 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EXF83814.1 - 6.4e-05 22.4 0.3 0.014 14.8 0.1 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EXF83814.1 - 6.8e-05 22.1 0.3 0.0033 16.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Arch_ATPase PF01637.13 EXF83814.1 - 0.0001 22.0 0.0 0.037 13.7 0.0 2.5 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 EXF83814.1 - 0.0001 22.4 0.0 0.054 13.6 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EXF83814.1 - 0.00072 19.0 1.5 0.023 14.2 0.1 3.2 3 0 0 3 3 3 1 P-loop containing region of AAA domain UPF0079 PF02367.12 EXF83814.1 - 0.0009 18.8 0.2 0.073 12.7 0.2 2.3 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 AAA_21 PF13304.1 EXF83814.1 - 0.002 18.1 0.0 1.1 9.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EXF83814.1 - 0.0022 18.7 0.0 0.22 12.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EXF83814.1 - 0.0053 16.6 0.0 0.25 11.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EXF83814.1 - 0.0054 16.2 0.1 0.51 9.8 0.1 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EXF83814.1 - 0.0068 15.8 0.3 0.36 10.2 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.7 EXF83814.1 - 0.009 15.6 0.2 0.52 9.9 0.1 2.6 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 EXF83814.1 - 0.013 15.2 0.1 6.4 6.6 0.1 2.8 2 0 0 2 2 2 0 Part of AAA domain AAA PF00004.24 EXF83814.1 - 0.026 14.7 0.0 8.1 6.6 0.0 3.1 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EXF83814.1 - 0.038 13.9 0.0 0.15 12.0 0.1 2.0 2 0 0 2 2 1 0 AAA domain SbcCD_C PF13558.1 EXF83814.1 - 0.043 13.7 0.0 0.58 10.1 0.0 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EXF83814.1 - 0.058 13.7 0.0 1.8 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EXF83814.1 - 0.07 13.6 0.0 1.7 9.1 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_30 PF13604.1 EXF83814.1 - 0.098 12.2 0.1 0.9 9.0 0.1 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EXF83814.1 - 0.28 10.2 0.1 6 5.8 0.1 2.2 2 0 0 2 2 2 0 Zeta toxin EVC2_like PF12297.3 EXF83814.1 - 0.39 9.2 0.0 0.64 8.5 0.0 1.2 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Cu-oxidase_3 PF07732.10 EXF83821.1 - 8.9e-48 160.9 9.1 6e-43 145.3 0.3 3.9 3 2 1 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EXF83821.1 - 4.3e-37 126.6 10.3 1.8e-33 114.9 2.2 3.8 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 EXF83821.1 - 3.1e-34 118.1 1.6 5e-33 114.2 0.1 2.7 3 0 0 3 3 3 1 Multicopper oxidase Shikimate_dh_N PF08501.6 EXF83822.1 - 3.6e-18 65.3 0.0 6.3e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EXF83822.1 - 1.6e-10 41.2 0.0 2.4e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AP_endonuc_2 PF01261.19 EXF83823.1 - 6.6e-26 90.9 0.1 1.1e-25 90.1 0.0 1.4 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel IucA_IucC PF04183.7 EXF83823.1 - 0.019 14.2 0.0 0.029 13.6 0.0 1.2 1 0 0 1 1 1 0 IucA / IucC family Fungal_trans PF04082.13 EXF83824.1 - 3.6e-10 39.1 0.7 6.2e-10 38.3 0.5 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF83824.1 - 1.5e-06 27.9 11.7 2.7e-06 27.1 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AAA PF00004.24 EXF83825.1 - 5.8e-19 68.5 0.0 1.1e-18 67.7 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EXF83825.1 - 0.00016 21.5 0.0 0.00037 20.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EXF83825.1 - 0.00026 21.0 0.1 0.0011 18.9 0.0 1.8 1 1 1 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EXF83825.1 - 0.0003 21.6 1.0 0.0025 18.6 0.2 2.9 2 1 0 2 2 2 1 AAA domain Zot PF05707.7 EXF83825.1 - 0.00049 19.6 0.5 0.0049 16.3 0.4 2.2 1 1 0 1 1 1 1 Zonular occludens toxin (Zot) AAA_22 PF13401.1 EXF83825.1 - 0.00088 19.4 0.1 0.0095 16.0 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 EXF83825.1 - 0.0044 16.8 0.0 0.017 15.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EXF83825.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Kinesin PF00225.18 EXF83825.1 - 0.017 13.8 0.0 0.028 13.1 0.0 1.3 1 0 0 1 1 1 0 Kinesin motor domain AAA_5 PF07728.9 EXF83825.1 - 0.019 14.6 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EXF83825.1 - 0.02 14.3 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.1 EXF83825.1 - 0.03 14.6 0.1 0.1 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EXF83825.1 - 0.034 13.2 0.0 0.066 12.2 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.1 EXF83825.1 - 0.046 13.2 0.0 0.094 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.8 EXF83825.1 - 0.058 12.1 0.0 0.088 11.4 0.0 1.2 1 0 0 1 1 1 0 TIP49 C-terminus AAA_19 PF13245.1 EXF83825.1 - 0.079 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain NACHT PF05729.7 EXF83825.1 - 0.11 12.1 0.1 0.6 9.7 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Viral_helicase1 PF01443.13 EXF83825.1 - 0.13 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase Rhabdo_M1 PF03342.8 EXF83826.1 - 0.0046 16.1 0.7 0.008 15.3 0.5 1.3 1 0 0 1 1 1 1 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) DHquinase_II PF01220.14 EXF83827.1 - 1e-61 206.3 0.4 1.2e-61 206.1 0.3 1.0 1 0 0 1 1 1 1 Dehydroquinase class II ADH_zinc_N PF00107.21 EXF83827.1 - 0.039 13.5 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase SnoaL_4 PF13577.1 EXF83828.1 - 2.2e-06 27.5 0.1 3.2e-06 27.0 0.1 1.1 1 0 0 1 1 1 1 SnoaL-like domain Shikimate_dh_N PF08501.6 EXF83829.1 - 2.9e-21 75.3 0.1 5.2e-21 74.5 0.1 1.4 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain Shikimate_DH PF01488.15 EXF83829.1 - 5.4e-13 49.1 0.0 9.3e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DHquinase_I PF01487.10 EXF83830.1 - 1.3e-31 109.9 0.0 2e-31 109.3 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.6 EXF83830.1 - 2.9e-20 72.1 0.0 7.4e-20 70.8 0.0 1.8 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SKI PF01202.17 EXF83830.1 - 2.9e-17 62.9 0.0 5.5e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase Shikimate_DH PF01488.15 EXF83830.1 - 2.1e-11 44.0 0.0 4.3e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase AAA_17 PF13207.1 EXF83830.1 - 1.3e-05 25.9 0.0 2.9e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain ThiF PF00899.16 EXF83830.1 - 0.034 13.9 0.4 0.26 11.1 0.1 2.2 2 0 0 2 2 2 0 ThiF family AAA_33 PF13671.1 EXF83830.1 - 0.039 13.8 0.0 0.31 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain F420_oxidored PF03807.12 EXF83830.1 - 0.053 13.9 0.0 0.24 11.8 0.0 2.1 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 EXF83830.1 - 0.071 13.3 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ABC2_membrane PF01061.19 EXF83831.1 - 7.9e-84 280.0 50.4 5.3e-46 156.4 12.6 2.5 2 0 0 2 2 2 2 ABC-2 type transporter PDR_CDR PF06422.7 EXF83831.1 - 2.9e-39 132.8 5.2 5e-33 112.8 0.0 3.6 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 EXF83831.1 - 4.8e-32 111.1 0.0 4.1e-16 59.5 0.0 3.5 4 0 0 4 4 4 2 ABC transporter ABC_trans_N PF14510.1 EXF83831.1 - 3.9e-19 68.5 0.1 9e-19 67.3 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EXF83831.1 - 3.4e-11 42.9 0.0 5.2e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EXF83831.1 - 7.5e-08 32.5 0.8 0.00012 22.1 0.1 2.4 2 0 0 2 2 2 2 AAA ATPase domain ABC2_membrane_3 PF12698.2 EXF83831.1 - 1.1e-07 31.2 31.7 0.00054 19.0 7.7 3.0 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_33 PF13671.1 EXF83831.1 - 2.1e-07 30.9 0.0 0.0046 16.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EXF83831.1 - 3.3e-07 29.7 1.0 0.00022 20.6 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 EXF83831.1 - 1.7e-05 24.8 0.0 0.008 16.1 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EXF83831.1 - 2e-05 25.3 0.0 0.008 16.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EXF83831.1 - 4.2e-05 22.7 0.0 0.0043 16.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 cobW PF02492.14 EXF83831.1 - 6.8e-05 22.3 1.6 0.011 15.2 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SMC_N PF02463.14 EXF83831.1 - 0.00018 20.8 0.0 0.11 11.7 0.0 2.8 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EXF83831.1 - 0.00022 21.5 0.0 0.11 12.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EXF83831.1 - 0.00044 20.4 0.0 0.58 10.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EXF83831.1 - 0.00072 19.2 1.4 0.28 10.9 0.1 2.7 2 0 0 2 2 2 1 Part of AAA domain AAA_14 PF13173.1 EXF83831.1 - 0.00075 19.4 0.0 0.46 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EXF83831.1 - 0.0014 18.6 0.0 0.024 14.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain PDR_assoc PF08370.6 EXF83831.1 - 0.0025 17.2 3.3 0.18 11.3 0.0 3.9 3 0 0 3 3 3 1 Plant PDR ABC transporter associated NACHT PF05729.7 EXF83831.1 - 0.0028 17.3 0.6 0.72 9.4 0.0 2.7 3 0 0 3 3 2 1 NACHT domain AAA_23 PF13476.1 EXF83831.1 - 0.0033 17.7 0.0 0.01 16.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.24 EXF83831.1 - 0.0046 17.1 0.0 4 7.6 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EXF83831.1 - 0.0057 16.3 0.1 0.52 10.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) T2SE PF00437.15 EXF83831.1 - 0.0087 14.9 0.0 0.92 8.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein RNA_helicase PF00910.17 EXF83831.1 - 0.0092 16.1 0.0 1 9.5 0.0 3.1 3 0 0 3 3 2 1 RNA helicase AAA_10 PF12846.2 EXF83831.1 - 0.018 14.4 0.1 1.9 7.8 0.0 2.8 3 0 0 3 3 2 0 AAA-like domain MMR_HSR1 PF01926.18 EXF83831.1 - 0.02 14.8 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EXF83831.1 - 0.027 13.9 0.8 13 5.2 0.0 3.4 4 0 0 4 4 3 0 FtsK/SpoIIIE family UPF0079 PF02367.12 EXF83831.1 - 0.041 13.4 0.4 0.83 9.2 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EXF83831.1 - 0.052 13.1 0.2 0.94 9.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EXF83831.1 - 0.053 13.0 0.2 8.5 5.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EXF83831.1 - 0.076 12.4 0.0 3.2 7.1 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 EXF83831.1 - 0.08 12.6 0.0 4 7.0 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase Miro PF08477.8 EXF83831.1 - 0.14 12.6 0.0 10 6.6 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein Zeta_toxin PF06414.7 EXF83831.1 - 0.22 10.5 0.0 5.6 6.0 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin PduV-EutP PF10662.4 EXF83831.1 - 0.25 10.8 0.4 1.6 8.2 0.1 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_15 PF13175.1 EXF83831.1 - 0.42 9.6 0.0 0.75 8.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.10 EXF83831.1 - 0.56 8.8 0.0 2.8 6.5 0.0 1.8 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein CENP-T PF15511.1 EXF83832.1 - 0.026 13.7 1.4 0.032 13.4 0.9 1.0 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T FHA PF00498.21 EXF83833.1 - 6.4e-18 64.6 0.2 1.9e-17 63.1 0.1 2.0 2 0 0 2 2 2 1 FHA domain Uds1 PF15456.1 EXF83833.1 - 0.024 14.6 11.4 0.11 12.4 1.3 2.7 2 0 0 2 2 2 0 Up-regulated During Septation DUF4047 PF13256.1 EXF83833.1 - 0.41 10.6 4.0 0.15 12.0 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Mnd1 PF03962.10 EXF83833.1 - 1.9 8.1 14.1 2.5 7.7 1.1 2.3 2 0 0 2 2 2 0 Mnd1 family GAS PF13851.1 EXF83833.1 - 6.3 5.9 13.1 0.48 9.5 1.6 2.4 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Romo1 PF10247.4 EXF83834.1 - 1.3e-25 89.3 13.6 2.1e-25 88.6 9.4 1.3 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_OmpA PF13436.1 EXF83834.1 - 0.22 11.2 2.8 0.29 10.7 1.9 1.3 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Tim17 PF02466.14 EXF83834.1 - 2.8 8.0 8.5 6.7 6.7 5.9 1.7 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family GMC_oxred_N PF00732.14 EXF83835.1 - 3.3e-60 203.7 0.0 2.4e-58 197.6 0.0 2.2 1 1 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF83835.1 - 8.3e-37 126.6 0.0 1.4e-36 125.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EXF83835.1 - 4.1e-07 29.2 0.2 9.1e-05 21.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF83835.1 - 3.3e-05 23.8 0.1 7.9e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EXF83835.1 - 9.5e-05 21.4 3.1 0.0026 16.6 2.1 2.2 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EXF83835.1 - 0.00049 19.1 0.2 0.00073 18.5 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EXF83835.1 - 0.0013 18.7 0.0 0.021 14.7 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF83835.1 - 0.0054 15.2 0.1 0.049 12.1 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.1 EXF83835.1 - 0.012 15.7 0.1 0.38 10.7 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF83835.1 - 0.015 14.3 0.1 0.035 13.2 0.1 1.5 1 0 0 1 1 1 0 Thi4 family TrkA_N PF02254.13 EXF83835.1 - 0.07 13.1 0.0 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_9 PF13454.1 EXF83835.1 - 0.12 12.1 0.2 0.28 10.9 0.1 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding Trp_halogenase PF04820.9 EXF83835.1 - 0.18 10.4 0.3 0.27 9.8 0.2 1.2 1 0 0 1 1 1 0 Tryptophan halogenase K_oxygenase PF13434.1 EXF83835.1 - 0.22 10.4 0.0 0.39 9.5 0.0 1.3 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Asp PF00026.18 EXF83836.1 - 4.4e-46 157.5 0.6 6.2e-46 157.0 0.4 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EXF83836.1 - 0.00055 19.9 0.8 0.0017 18.3 0.6 1.9 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal MFS_1 PF07690.11 EXF83837.1 - 3.9e-35 121.2 12.7 8.6e-27 93.7 4.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EXF83837.1 - 0.0051 16.5 0.9 0.13 12.0 0.6 2.5 2 0 0 2 2 2 1 MFS_1 like family Fungal_trans_2 PF11951.3 EXF83838.1 - 6.4e-43 146.8 0.0 8.1e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 EXF83839.1 - 1.3e-21 77.4 0.5 1.6e-21 77.2 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF83839.1 - 5.5e-10 39.1 0.2 1.5e-09 37.7 0.2 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF83839.1 - 1.9e-05 24.3 0.0 9.7e-05 22.0 0.0 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Ndr PF03096.9 EXF83839.1 - 0.0017 16.8 0.0 0.0026 16.3 0.0 1.3 1 0 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 EXF83839.1 - 0.0078 16.0 0.0 0.021 14.6 0.0 1.7 1 1 0 1 1 1 1 Putative lysophospholipase Peptidase_S15 PF02129.13 EXF83839.1 - 0.047 13.1 1.0 0.096 12.0 0.7 1.8 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Sugarporin_N PF11471.3 EXF83839.1 - 0.33 10.6 0.1 0.33 10.6 0.1 1.7 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Fungal_trans PF04082.13 EXF83840.1 - 6.8e-14 51.3 0.0 1.1e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain ABC2_membrane PF01061.19 EXF83841.1 - 2.3e-90 301.3 59.1 9.7e-49 165.3 17.0 2.5 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 EXF83841.1 - 7.9e-40 136.3 0.0 7.5e-19 68.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EXF83841.1 - 2.3e-29 101.0 6.3 1.6e-27 95.1 0.0 3.4 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 EXF83841.1 - 2.3e-14 53.2 35.0 1.3e-08 34.3 10.5 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 EXF83841.1 - 1.5e-08 34.6 0.0 5.3e-08 32.8 0.0 2.0 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EXF83841.1 - 1.9e-06 27.3 0.0 0.0043 16.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EXF83841.1 - 2e-05 24.7 0.1 0.057 13.5 0.0 3.1 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 EXF83841.1 - 5.2e-05 22.4 0.0 0.0047 16.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 EXF83841.1 - 9.1e-05 22.3 0.1 0.67 9.8 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_28 PF13521.1 EXF83841.1 - 0.0001 22.2 0.1 0.24 11.3 0.0 2.4 2 0 0 2 2 2 2 AAA domain cobW PF02492.14 EXF83841.1 - 0.00015 21.2 0.3 0.28 10.6 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 EXF83841.1 - 0.00018 21.5 0.2 0.13 12.2 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EXF83841.1 - 0.00084 18.8 0.4 0.08 12.4 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EXF83841.1 - 0.0021 18.8 0.0 0.63 10.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EXF83841.1 - 0.0047 17.2 0.0 1.5 9.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EXF83841.1 - 0.008 15.9 0.5 1.6 8.5 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 EXF83841.1 - 0.012 15.2 0.6 3.7 7.1 0.2 2.5 2 0 0 2 2 2 0 NACHT domain T2SE PF00437.15 EXF83841.1 - 0.013 14.4 0.0 0.82 8.5 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein PduV-EutP PF10662.4 EXF83841.1 - 0.031 13.7 0.5 1.5 8.3 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Arch_ATPase PF01637.13 EXF83841.1 - 0.041 13.5 0.0 9.7 5.8 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase MMR_HSR1 PF01926.18 EXF83841.1 - 0.083 12.8 0.0 8.7 6.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_21 PF13304.1 EXF83841.1 - 0.093 12.6 0.0 1.8 8.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 EXF83841.1 - 0.12 12.8 0.0 3.3 8.2 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 EXF83841.1 - 0.18 12.0 0.1 24 5.1 0.1 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RbsD_FucU PF05025.8 EXF83842.1 - 4.3e-38 130.8 0.0 4.8e-38 130.6 0.0 1.0 1 0 0 1 1 1 1 RbsD / FucU transport protein family DUF902 PF06001.8 EXF83843.1 - 0.069 13.2 0.1 7.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF902) AA_permease PF00324.16 EXF83844.1 - 1.1e-133 446.0 36.0 1.3e-133 445.8 24.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF83844.1 - 4.1e-35 121.1 38.9 5.4e-35 120.7 27.0 1.0 1 0 0 1 1 1 1 Amino acid permease Methyltransf_2 PF00891.13 EXF83845.1 - 4.7e-30 104.5 0.1 1.8e-29 102.6 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_25 PF13649.1 EXF83845.1 - 0.014 15.7 0.0 0.19 12.1 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 EXF83846.1 - 1.1e-36 126.2 50.3 1.6e-36 125.7 32.1 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily Afaf PF15339.1 EXF83846.1 - 0.22 11.1 0.1 0.35 10.4 0.0 1.3 1 0 0 1 1 1 0 Acrosome formation-associated factor EBP PF05241.7 EXF83847.1 - 4.2e-64 215.1 7.2 5.1e-64 214.8 5.0 1.0 1 0 0 1 1 1 1 Emopamil binding protein Asparaginase PF00710.15 EXF83848.1 - 1.2e-68 231.3 0.4 1.3e-68 231.1 0.3 1.0 1 0 0 1 1 1 1 Asparaginase Hce2 PF14856.1 EXF83849.1 - 1.9e-24 85.4 0.2 2.1e-08 33.9 0.1 3.4 3 0 0 3 3 3 3 Pathogen effector; putative necrosis-inducing factor PQ-loop PF04193.9 EXF83850.1 - 4.1e-05 23.0 0.1 4.1e-05 23.0 0.1 2.9 3 0 0 3 3 3 1 PQ loop repeat TctB PF07331.6 EXF83850.1 - 0.29 10.7 8.0 3.8 7.1 3.9 2.6 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family PRA1 PF03208.14 EXF83850.1 - 2.9 7.2 9.0 0.12 11.7 1.8 2.0 2 1 0 2 2 2 0 PRA1 family protein Peptidase_M28 PF04389.12 EXF83851.1 - 2.1e-28 99.2 0.0 3e-28 98.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EXF83851.1 - 4.2e-05 23.1 0.0 6.9e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Prolamin_like PF05617.6 EXF83853.1 - 1.4 9.1 6.0 3.5 7.8 0.4 2.2 2 0 0 2 2 2 0 Prolamin-like 2OG-FeII_Oxy PF03171.15 EXF83855.1 - 8.2e-13 48.5 0.0 1.3e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EXF83855.1 - 7.1e-09 36.2 0.0 1.4e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Amidohydro_4 PF13147.1 EXF83856.1 - 1.1e-11 45.2 14.2 6.5e-10 39.4 0.1 3.6 3 0 0 3 3 3 2 Amidohydrolase Amidohydro_1 PF01979.15 EXF83856.1 - 3e-07 30.4 2.9 2e-06 27.6 2.0 2.4 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EXF83856.1 - 6.2e-07 29.1 4.4 5.8e-06 26.0 0.2 2.9 3 0 0 3 3 3 1 Amidohydrolase Amidohydro_3 PF07969.6 EXF83856.1 - 3.3e-05 23.3 0.1 3.3e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase family PHD_2 PF13831.1 EXF83856.1 - 0.11 11.7 0.5 0.23 10.7 0.3 1.5 1 0 0 1 1 1 0 PHD-finger Glyco_hydro_20 PF00728.17 EXF83857.1 - 3.1e-35 121.9 1.0 1.9e-34 119.4 0.7 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.10 EXF83857.1 - 5.5e-07 30.1 0.0 1.1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DUF4121 PF13497.1 EXF83857.1 - 0.093 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) Ferric_reduct PF01794.14 EXF83858.1 - 2.8e-20 72.6 13.1 2.8e-20 72.6 9.1 2.5 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EXF83858.1 - 3.3e-15 55.8 0.0 6e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.7 EXF83858.1 - 2.6e-10 40.4 0.0 4.3e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DUF4405 PF14358.1 EXF83858.1 - 0.22 11.6 10.5 0.66 10.1 1.1 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4405) Ctr PF04145.10 EXF83859.1 - 1.6e-27 96.3 0.1 2e-27 95.9 0.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF3433 PF11915.3 EXF83860.1 - 7.3e-34 115.8 14.9 1.5e-19 69.9 0.1 3.7 3 0 0 3 3 3 2 Protein of unknown function (DUF3433) Fasciclin PF02469.17 EXF83861.1 - 7.2e-41 139.1 0.1 2.1e-20 73.0 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Cellulase PF00150.13 EXF83861.1 - 0.015 14.4 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) GMC_oxred_C PF05199.8 EXF83862.1 - 4.1e-06 27.1 0.0 1.2e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EXF83862.1 - 1.4e-05 24.3 0.1 0.0016 17.6 0.0 2.6 3 0 0 3 3 3 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EXF83862.1 - 7.3e-05 21.7 0.1 0.00013 21.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Abhydrolase_6 PF12697.2 EXF83862.1 - 0.00066 19.6 0.0 0.011 15.6 0.0 2.5 2 1 0 2 2 2 1 Alpha/beta hydrolase family FAD_oxidored PF12831.2 EXF83862.1 - 0.001 18.2 0.2 0.0017 17.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF83862.1 - 0.0016 18.3 0.1 0.0036 17.1 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF83862.1 - 0.0028 16.6 0.1 0.041 12.7 0.1 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF83862.1 - 0.0029 17.5 0.3 0.015 15.3 0.2 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EXF83862.1 - 0.011 16.1 0.0 0.034 14.5 0.0 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF83862.1 - 0.028 12.8 0.1 0.044 12.2 0.0 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.17 EXF83862.1 - 0.034 12.9 0.1 0.06 12.1 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Smoothelin PF12510.3 EXF83862.1 - 0.051 13.4 0.4 0.093 12.6 0.3 1.4 1 0 0 1 1 1 0 Smoothelin cytoskeleton protein Thi4 PF01946.12 EXF83862.1 - 0.09 11.8 0.0 0.21 10.6 0.0 1.5 1 0 0 1 1 1 0 Thi4 family FAD-oxidase_C PF02913.14 EXF83864.1 - 0.14 11.4 2.0 0.18 11.1 1.4 1.1 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain NARP1 PF12569.3 EXF83864.1 - 0.28 9.8 4.5 0.35 9.5 3.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF2229 PF09989.4 EXF83864.1 - 0.43 10.0 1.6 0.51 9.7 1.1 1.1 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) FLO_LFY PF01698.11 EXF83864.1 - 2 7.1 11.5 2.6 6.8 8.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein U79_P34 PF03064.11 EXF83864.1 - 2.2 7.7 12.1 2.9 7.3 8.4 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 bZIP_Maf PF03131.12 EXF83864.1 - 2.6 8.4 9.1 12 6.2 2.8 2.2 2 0 0 2 2 2 0 bZIP Maf transcription factor Serglycin PF04360.7 EXF83864.1 - 5.2 6.7 9.5 6 6.5 5.4 1.8 1 1 1 2 2 2 0 Serglycin MmgE_PrpD PF03972.9 EXF83865.1 - 2.9e-79 266.3 0.6 3.6e-79 266.0 0.4 1.0 1 0 0 1 1 1 1 MmgE/PrpD family 3Beta_HSD PF01073.14 EXF83867.1 - 1.7e-07 30.2 0.0 2.9e-07 29.4 0.0 1.3 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EXF83867.1 - 5.2e-06 26.0 0.2 8.4e-06 25.3 0.1 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EXF83867.1 - 4.8e-05 22.4 0.0 7.2e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EXF83867.1 - 0.00051 20.0 0.0 0.00099 19.1 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Glyco_hydro_61 PF03443.9 EXF83868.1 - 6.1e-60 202.7 0.1 8e-60 202.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Dehydratase_hem PF13816.1 EXF83870.1 - 8.7e-80 268.0 0.0 2.1e-79 266.7 0.0 1.5 1 1 0 1 1 1 1 Haem-containing dehydratase DUF1330 PF07045.6 EXF83870.1 - 0.072 12.9 0.0 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1330) DUF373 PF04123.8 EXF83871.1 - 0.47 9.4 6.7 0.72 8.8 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) adh_short PF00106.20 EXF83872.1 - 6.4e-22 78.2 0.2 8.7e-22 77.8 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF83872.1 - 7.9e-10 38.8 0.0 9.8e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF83872.1 - 1.3e-07 31.5 0.1 1.9e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.12 EXF83872.1 - 0.026 13.4 0.0 0.046 12.5 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 EXF83872.1 - 0.048 13.4 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EXF83872.1 - 0.051 13.5 0.1 0.11 12.5 0.0 1.7 1 1 0 1 1 1 0 NADH(P)-binding Pkinase PF00069.20 EXF83873.1 - 1.1e-21 77.2 0.0 9.8e-17 60.9 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EXF83873.1 - 0.013 14.5 0.0 0.046 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase NADH-u_ox-rdase PF10785.4 EXF83875.1 - 0.049 13.8 0.7 0.16 12.2 0.1 1.9 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit XAP5 PF04921.9 EXF83876.1 - 4.2e-83 278.5 0.0 6.9e-83 277.8 0.0 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator IER PF05760.7 EXF83876.1 - 0.35 10.7 3.6 0.48 10.3 2.5 1.2 1 0 0 1 1 1 0 Immediate early response protein (IER) Methyltransf_10 PF05971.7 EXF83878.1 - 1.5e-63 214.7 0.0 2.1e-63 214.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF890) Methyltransf_26 PF13659.1 EXF83878.1 - 3.8e-06 26.9 0.0 6.4e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF83878.1 - 9.5e-06 25.0 0.0 1.5e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EXF83878.1 - 0.00019 20.6 0.0 0.00049 19.3 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EXF83878.1 - 0.0014 19.1 0.0 0.003 18.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EXF83878.1 - 0.0049 16.4 0.0 0.0087 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Met_10 PF02475.11 EXF83878.1 - 0.022 14.3 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_31 PF13847.1 EXF83878.1 - 0.16 11.5 0.0 0.33 10.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain NmrA PF05368.8 EXF83879.1 - 6.2e-17 61.6 0.0 8e-17 61.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF83879.1 - 2.5e-14 53.6 1.4 1.1e-13 51.6 1.0 2.0 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EXF83879.1 - 2.6e-05 23.0 0.0 3.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EXF83879.1 - 0.00018 21.1 0.1 0.00054 19.6 0.0 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EXF83879.1 - 0.00022 20.7 0.1 0.00054 19.4 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EXF83879.1 - 0.0003 20.7 0.1 0.16 11.9 0.0 2.6 3 0 0 3 3 3 2 Dihydrodipicolinate reductase, N-terminus F420_oxidored PF03807.12 EXF83879.1 - 0.00033 21.0 0.1 0.0012 19.2 0.0 1.9 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent adh_short PF00106.20 EXF83879.1 - 0.00059 19.7 0.4 0.0063 16.4 0.1 2.3 2 1 0 2 2 2 1 short chain dehydrogenase Saccharop_dh PF03435.13 EXF83879.1 - 0.0044 16.0 0.0 0.0053 15.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EXF83879.1 - 0.008 16.2 0.0 0.015 15.3 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 EXF83879.1 - 0.11 12.8 0.1 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 EXF83879.1 - 0.13 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain Fungal_trans PF04082.13 EXF83880.1 - 2.3e-05 23.4 0.0 4.4e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF83880.1 - 2.8e-05 23.9 9.8 5.3e-05 23.0 6.8 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sir1 PF11603.3 EXF83880.1 - 0.15 12.2 0.1 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 Regulatory protein Sir1 Cellulase PF00150.13 EXF83882.1 - 3.2e-16 59.3 0.8 4.7e-16 58.8 0.5 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Ank PF00023.25 EXF83883.1 - 3.8e-14 51.6 0.6 0.00065 19.3 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EXF83883.1 - 1.7e-13 50.7 0.1 5e-12 46.0 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EXF83883.1 - 1.3e-12 46.6 0.0 0.0053 16.8 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EXF83883.1 - 1.9e-10 40.6 0.1 8.1e-05 22.7 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EXF83883.1 - 1.1e-06 28.9 0.1 0.0001 22.6 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) AAA_16 PF13191.1 EXF83883.1 - 2.9e-06 27.3 0.2 1.9e-05 24.7 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EXF83883.1 - 0.0026 17.4 0.0 0.0048 16.5 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Torsin PF06309.6 EXF83883.1 - 0.039 13.8 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Torsin RVT_1 PF00078.22 EXF83885.1 - 2.3e-32 112.0 0.0 4.1e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos_2 PF14529.1 EXF83885.1 - 2.4e-09 36.8 0.0 8.9e-09 34.9 0.0 2.0 2 0 0 2 2 2 1 Endonuclease-reverse transcriptase Exo_endo_phos PF03372.18 EXF83885.1 - 0.00084 19.3 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family GATase_4 PF13230.1 EXF83888.1 - 3.9e-11 42.1 0.0 7.3e-10 37.9 0.0 2.6 1 1 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EXF83888.1 - 1.1e-08 35.0 0.0 2.3e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain PAN_4 PF14295.1 EXF83889.1 - 0.018 14.7 1.8 0.19 11.4 1.3 2.3 1 1 0 1 1 1 0 PAN domain DUF3357 PF11837.3 EXF83889.1 - 0.044 13.6 0.5 0.15 11.8 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) PAN_1 PF00024.21 EXF83889.1 - 0.74 9.6 5.7 0.078 12.7 0.4 1.9 2 0 0 2 2 2 0 PAN domain BAF1_ABF1 PF04684.8 EXF83889.1 - 3.4 6.3 7.0 5 5.8 4.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Acetyltransf_3 PF13302.1 EXF83890.1 - 6.5e-25 87.9 0.0 7.7e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EXF83890.1 - 0.002 18.1 0.1 0.0031 17.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EXF83890.1 - 0.028 14.3 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain zf-C2H2_4 PF13894.1 EXF83891.1 - 1.1e-06 28.5 12.9 0.0049 17.1 0.4 3.6 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF83891.1 - 6.8e-05 22.9 12.8 0.0011 19.1 1.1 3.5 3 0 0 3 3 3 1 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EXF83891.1 - 0.1 12.8 8.2 0.81 10.1 0.3 3.6 3 0 0 3 3 3 0 Zinc-finger double domain zf-TRAF PF02176.13 EXF83891.1 - 2.4 8.5 9.1 0.38 11.1 0.6 3.3 2 1 1 4 4 4 0 TRAF-type zinc finger DUF4139 PF13598.1 EXF83892.1 - 2.1e-63 214.5 19.7 4.1e-46 157.7 1.9 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4139) DUF4140 PF13600.1 EXF83892.1 - 5.9e-11 42.7 4.2 5.9e-11 42.7 2.9 4.9 3 1 0 3 3 3 1 N-terminal domain of unknown function (DUF4140) UDPG_MGDP_dh_N PF03721.9 EXF83893.1 - 1.1e-49 168.3 0.0 1.8e-31 108.9 0.0 2.3 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 EXF83893.1 - 3.1e-32 110.6 0.0 9.4e-32 109.1 0.0 1.9 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain UDPG_MGDP_dh_C PF03720.10 EXF83893.1 - 1.5e-18 66.9 0.0 3.1e-17 62.6 0.0 2.4 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain NAD_Gly3P_dh_N PF01210.18 EXF83893.1 - 0.0021 17.8 0.0 1.7 8.3 0.1 3.0 2 1 0 2 2 2 2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 EXF83893.1 - 0.0075 15.2 0.0 0.012 14.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_2 PF03446.10 EXF83893.1 - 0.022 14.5 0.0 2.5 7.9 0.0 2.8 2 1 0 2 2 2 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EXF83893.1 - 0.058 13.0 0.0 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glycos_transf_1 PF00534.15 EXF83894.1 - 8.7e-36 122.9 0.0 1.4e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EXF83894.1 - 4.9e-17 62.3 0.0 8.8e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EXF83894.1 - 3.5e-16 59.7 0.2 7.2e-16 58.7 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EXF83894.1 - 2.4e-12 46.9 0.0 5.8e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EXF83894.1 - 2.7e-05 23.9 0.1 9.1e-05 22.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Fungal_trans PF04082.13 EXF83897.1 - 3.5e-28 98.1 0.2 5.1e-28 97.6 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF83897.1 - 7.7e-06 25.7 6.7 1.3e-05 25.0 4.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ECH PF00378.15 EXF83898.1 - 5.2e-39 133.8 0.0 6.4e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family p450 PF00067.17 EXF83899.1 - 1.8e-72 244.3 0.0 2.5e-72 243.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EXF83899.1 - 6.4e-39 133.6 0.1 1.5e-38 132.4 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.20 EXF83899.1 - 1.3e-23 83.5 0.0 2.7e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EXF83899.1 - 3.7e-14 53.2 0.0 9.3e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EXF83899.1 - 0.068 13.2 0.0 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 Oxidoreductase FAD-binding domain Flavodoxin_NdrI PF07972.6 EXF83899.1 - 0.16 11.8 0.0 0.47 10.3 0.0 1.8 1 0 0 1 1 1 0 NrdI Flavodoxin like AMP-binding PF00501.23 EXF83900.1 - 2e-37 128.5 0.0 5.8e-37 127.0 0.0 1.7 2 0 0 2 2 2 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EXF83900.1 - 1.1e-33 116.2 0.0 1.8e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EXF83900.1 - 2.9e-09 36.7 0.0 5.7e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EXF83900.1 - 0.00031 20.9 0.0 0.0011 19.1 0.0 1.9 1 1 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.20 EXF83900.1 - 0.046 13.6 0.0 0.12 12.2 0.0 1.8 1 1 0 1 1 1 0 short chain dehydrogenase Cu-oxidase_2 PF07731.9 EXF83901.1 - 2.1e-42 143.9 9.4 3.9e-40 136.5 0.8 4.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EXF83901.1 - 3.7e-42 142.7 13.5 1.1e-40 138.0 2.1 3.9 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase PF00394.17 EXF83901.1 - 2.3e-34 118.6 2.3 2.1e-33 115.4 0.2 2.8 3 0 0 3 3 3 1 Multicopper oxidase DUF706 PF05153.10 EXF83902.1 - 8e-125 415.2 0.2 1.2e-124 414.6 0.2 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF706) HD PF01966.17 EXF83902.1 - 0.0062 16.5 0.0 0.49 10.4 0.0 2.4 2 0 0 2 2 2 2 HD domain Fungal_trans_2 PF11951.3 EXF83903.1 - 1.2e-06 27.3 0.2 3.6e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF83903.1 - 2.6e-05 24.0 7.6 4.9e-05 23.1 5.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EXF83904.1 - 5.2e-83 279.1 19.0 6.1e-83 278.8 13.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF83904.1 - 2.8e-16 59.2 20.6 4.2e-14 52.0 12.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3226 PF11536.3 EXF83904.1 - 0.11 11.9 0.0 7.5 5.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3226) DUF4131 PF13567.1 EXF83904.1 - 0.41 10.0 0.0 0.41 10.0 0.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) MFS_1 PF07690.11 EXF83905.1 - 8.3e-36 123.4 26.2 8.3e-36 123.4 18.2 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Rhomboid PF01694.17 EXF83905.1 - 3 7.8 18.5 0.34 10.9 1.4 3.8 3 1 1 4 4 4 0 Rhomboid family Fungal_trans PF04082.13 EXF83906.1 - 8.2e-26 90.4 0.0 1.2e-25 89.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF83906.1 - 4.6e-08 32.8 9.7 8e-08 32.0 6.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Aldo_ket_red PF00248.16 EXF83907.1 - 2.6e-56 190.5 0.0 3.2e-56 190.2 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family NAD_binding_4 PF07993.7 EXF83908.1 - 1.5e-42 145.2 0.1 2.5e-42 144.5 0.1 1.4 1 0 0 1 1 1 1 Male sterility protein AMP-binding PF00501.23 EXF83908.1 - 1.5e-38 132.2 0.0 3e-38 131.2 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme AAA_33 PF13671.1 EXF83908.1 - 5.9e-12 45.6 0.0 1.7e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Epimerase PF01370.16 EXF83908.1 - 8.6e-12 44.9 0.1 3.3e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family SKI PF01202.17 EXF83908.1 - 3.6e-10 39.9 0.0 6.9e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Shikimate kinase PP-binding PF00550.20 EXF83908.1 - 2.3e-09 37.3 0.5 7.2e-09 35.7 0.2 2.1 2 0 0 2 2 1 1 Phosphopantetheine attachment site AAA_17 PF13207.1 EXF83908.1 - 3.7e-08 34.2 0.0 1.4e-07 32.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EXF83908.1 - 9e-07 29.2 0.0 3.5e-06 27.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EXF83908.1 - 1.8e-06 27.7 0.0 3.3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase AAA_25 PF13481.1 EXF83908.1 - 2.2e-05 23.9 0.0 5.5e-05 22.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain adh_short PF00106.20 EXF83908.1 - 0.00016 21.6 4.2 0.00054 19.9 1.5 2.8 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EXF83908.1 - 0.00018 21.1 2.2 0.0049 16.5 0.4 2.5 2 0 0 2 2 2 1 KR domain AAA_16 PF13191.1 EXF83908.1 - 0.00054 19.9 0.3 0.0022 18.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 EXF83908.1 - 0.00058 19.0 0.0 0.0012 17.9 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin 3Beta_HSD PF01073.14 EXF83908.1 - 0.00063 18.5 0.0 0.0018 17.0 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AAA PF00004.24 EXF83908.1 - 0.002 18.3 0.1 0.0066 16.6 0.1 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MobB PF03205.9 EXF83908.1 - 0.0042 16.7 0.0 0.009 15.7 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CobU PF02283.11 EXF83908.1 - 0.016 14.6 0.5 1.3 8.4 0.0 2.5 2 0 0 2 2 2 0 Cobinamide kinase / cobinamide phosphate guanyltransferase AAA_PrkA PF08298.6 EXF83908.1 - 0.017 13.8 0.0 0.035 12.7 0.0 1.4 1 0 0 1 1 1 0 PrkA AAA domain Polysacc_synt_2 PF02719.10 EXF83908.1 - 0.021 13.7 0.0 0.035 12.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ABC_tran PF00005.22 EXF83908.1 - 0.025 14.8 0.0 0.058 13.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EXF83908.1 - 0.03 13.8 0.2 0.09 12.3 0.0 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain Cytidylate_kin2 PF13189.1 EXF83908.1 - 0.037 13.9 0.0 0.096 12.5 0.0 1.8 1 0 0 1 1 1 0 Cytidylate kinase-like family Semialdhyde_dh PF01118.19 EXF83908.1 - 0.042 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain AAA_19 PF13245.1 EXF83908.1 - 0.048 13.4 1.1 0.28 10.9 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 EXF83908.1 - 0.06 12.9 0.0 0.16 11.6 0.0 1.7 1 0 0 1 1 1 0 NACHT domain B12-binding PF02310.14 EXF83908.1 - 0.076 12.8 0.1 4.3 7.2 0.0 3.4 3 1 1 4 4 2 0 B12 binding domain IstB_IS21 PF01695.12 EXF83908.1 - 0.076 12.4 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SE PF00437.15 EXF83908.1 - 0.078 11.8 0.8 0.21 10.4 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.1 EXF83908.1 - 0.084 13.0 0.0 0.28 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EXF83908.1 - 0.098 11.8 0.1 0.21 10.7 0.1 1.5 1 0 0 1 1 1 0 PhoH-like protein DapB_N PF01113.15 EXF83908.1 - 0.14 12.0 0.0 0.51 10.2 0.0 2.0 2 0 0 2 2 1 0 Dihydrodipicolinate reductase, N-terminus KTI12 PF08433.5 EXF83908.1 - 0.17 11.0 0.0 0.36 10.0 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 NTPase_1 PF03266.10 EXF83908.1 - 0.21 11.2 0.0 0.41 10.3 0.0 1.5 1 0 0 1 1 1 0 NTPase Lactamase_B PF00753.22 EXF83909.1 - 8.7e-12 45.0 0.2 1.5e-11 44.3 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EXF83909.1 - 0.0006 19.4 0.3 0.0037 16.8 0.2 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Varsurf_PPLC PF03490.8 EXF83910.1 - 0.002 17.7 0.0 0.0072 15.9 0.0 2.0 2 0 0 2 2 2 1 Variant-surface-glycoprotein phospholipase C Macro PF01661.16 EXF83911.1 - 9.9e-25 86.7 0.0 1.8e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 Macro domain DUF3129 PF11327.3 EXF83912.1 - 3.6e-57 193.1 12.1 4.7e-57 192.7 8.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3129) Amino_oxidase PF01593.19 EXF83913.1 - 8.4e-31 107.5 0.1 5e-23 81.9 0.1 2.0 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EXF83913.1 - 2.2e-06 27.5 0.0 6e-06 26.1 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pkinase PF00069.20 EXF83914.1 - 2.8e-23 82.3 0.0 4.4e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF83914.1 - 1.4e-10 40.6 0.0 2.2e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EXF83914.1 - 0.25 10.0 0.1 0.4 9.4 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.20 EXF83915.1 - 1.4e-18 67.0 0.0 2e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain CorA PF01544.13 EXF83916.1 - 0.085 11.8 8.0 0.17 10.9 5.5 1.6 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein DUF3328 PF11807.3 EXF83920.1 - 1.6e-25 90.1 2.8 2e-25 89.7 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3328 PF11807.3 EXF83921.1 - 1.7e-28 99.7 4.3 2.2e-28 99.4 3.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) DUF3357 PF11837.3 EXF83921.1 - 0.11 12.4 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Fip1 PF05182.8 EXF83922.1 - 5.1e-21 73.6 0.6 9.9e-21 72.7 0.4 1.5 1 0 0 1 1 1 1 Fip1 motif Herpes_UL32 PF06070.6 EXF83922.1 - 0.045 12.2 7.4 0.057 11.8 5.1 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 Myc_N PF01056.13 EXF83922.1 - 1.6 7.7 14.7 0.78 8.8 7.0 2.0 1 1 1 2 2 2 0 Myc amino-terminal region Nucleoporin_FG PF13634.1 EXF83923.1 - 5.4e-22 78.1 115.5 1.3e-13 51.1 34.6 3.4 2 1 0 3 3 3 2 Nucleoporin FG repeat region Tup_N PF08581.5 EXF83923.1 - 0.13 12.4 1.4 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 Tup N-terminal RNA_pol_3_Rpc31 PF11705.3 EXF83924.1 - 9.8e-39 133.6 3.3 1.5e-38 133.0 2.3 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 MFS_1 PF07690.11 EXF83925.1 - 7.8e-39 133.3 42.6 7.8e-39 133.3 29.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF83925.1 - 5.2e-11 41.7 30.2 2.8e-10 39.3 21.2 1.8 1 1 1 2 2 2 1 Sugar (and other) transporter Prefoldin_2 PF01920.15 EXF83926.1 - 2.2e-26 91.6 10.3 2.2e-26 91.6 7.2 1.4 2 0 0 2 2 2 1 Prefoldin subunit DUF3496 PF12001.3 EXF83926.1 - 0.038 14.2 7.7 0.15 12.3 1.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) PilJ PF13675.1 EXF83926.1 - 0.053 13.8 1.4 0.58 10.5 1.0 2.1 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term Nup54 PF13874.1 EXF83926.1 - 0.075 12.6 1.9 2.5 7.7 0.1 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Baculo_PEP_C PF04513.7 EXF83926.1 - 0.12 12.2 0.4 0.23 11.2 0.0 1.6 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus WXG100 PF06013.7 EXF83926.1 - 0.15 12.0 1.1 0.23 11.4 0.1 1.7 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF2730 PF10805.3 EXF83926.1 - 0.33 10.7 6.5 0.56 9.9 0.3 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) Prefoldin PF02996.12 EXF83926.1 - 0.38 10.4 7.7 0.08 12.5 0.9 2.2 1 1 1 2 2 2 0 Prefoldin subunit FlaC_arch PF05377.6 EXF83926.1 - 0.42 10.5 8.8 0.27 11.1 1.1 2.6 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Atg14 PF10186.4 EXF83926.1 - 0.42 9.5 3.5 0.45 9.3 1.8 1.3 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 eIF-4B PF06273.6 EXF83926.1 - 0.46 9.1 6.9 0.54 8.9 4.8 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DUF1664 PF07889.7 EXF83926.1 - 0.5 10.1 5.6 0.09 12.5 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Bap31 PF05529.7 EXF83926.1 - 0.68 9.3 7.3 3.5 7.0 0.1 2.0 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF1640 PF07798.6 EXF83926.1 - 0.78 9.7 7.2 1.6 8.7 5.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF1319 PF07028.6 EXF83926.1 - 0.9 9.7 9.9 1.1 9.4 3.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) Fib_alpha PF08702.5 EXF83926.1 - 0.94 9.5 5.6 2.1 8.4 3.9 1.6 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4164 PF13747.1 EXF83926.1 - 2.9 8.0 12.2 1.6 8.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) Syntaxin-6_N PF09177.6 EXF83926.1 - 3.1 8.2 8.2 3.1 8.2 0.4 2.2 1 1 0 2 2 2 0 Syntaxin 6, N-terminal Nsp1_C PF05064.8 EXF83926.1 - 5.7 6.6 9.5 0.73 9.4 0.3 2.3 2 1 0 2 2 2 0 Nsp1-like C-terminal region Seryl_tRNA_N PF02403.17 EXF83926.1 - 6 6.9 13.4 1.4 9.0 0.2 2.5 2 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain bZIP_1 PF00170.16 EXF83926.1 - 8.4 6.4 10.0 0.75 9.8 0.8 2.2 2 0 0 2 2 2 0 bZIP transcription factor ORF6C PF10552.4 EXF83926.1 - 9.1 6.0 7.8 0.57 9.9 0.2 2.3 2 1 0 2 2 2 0 ORF6C domain Pinin_SDK_memA PF04696.8 EXF83928.1 - 3 7.4 12.4 0.24 10.9 4.5 2.0 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region ARGLU PF15346.1 EXF83928.1 - 9.4 6.0 20.5 0.14 11.8 8.9 1.9 2 1 0 2 2 2 0 Arginine and glutamate-rich 1 FAD_binding_4 PF01565.18 EXF83929.1 - 1.1e-17 63.7 2.9 1.1e-17 63.7 2.0 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EXF83929.1 - 1.1e-13 50.8 0.6 1.1e-13 50.8 0.4 2.1 2 0 0 2 2 2 1 Berberine and berberine like DNA_binding_1 PF01035.15 EXF83930.1 - 2.1e-25 88.2 0.0 3.1e-25 87.7 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain ubiquitin PF00240.18 EXF83931.1 - 0.00031 20.0 0.0 0.00047 19.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.5 EXF83931.1 - 0.016 15.7 0.0 0.026 15.0 0.0 1.3 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD AAA PF00004.24 EXF83932.1 - 1.6e-50 170.7 0.0 7.6e-38 129.6 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EXF83932.1 - 2.4e-09 37.4 0.1 0.0019 18.3 0.0 4.2 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EXF83932.1 - 7.9e-09 35.4 0.0 0.00038 20.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.8 EXF83932.1 - 4.3e-07 28.9 0.0 0.016 13.9 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_17 PF13207.1 EXF83932.1 - 1.6e-06 28.9 0.0 0.0067 17.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EXF83932.1 - 1.8e-06 27.5 0.2 0.034 13.8 0.0 3.3 3 0 0 3 3 3 2 Part of AAA domain AAA_2 PF07724.9 EXF83932.1 - 3e-06 27.2 0.0 4.1e-05 23.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EXF83932.1 - 4.2e-06 26.5 0.0 0.0016 18.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EXF83932.1 - 8.2e-06 25.6 0.2 4.6 6.8 0.1 4.4 2 2 2 4 4 4 0 Archaeal ATPase AAA_18 PF13238.1 EXF83932.1 - 1.6e-05 25.2 0.0 0.0036 17.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EXF83932.1 - 2.3e-05 23.6 0.1 0.0036 16.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EXF83932.1 - 5.7e-05 23.1 0.1 0.053 13.5 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain RNA_helicase PF00910.17 EXF83932.1 - 7.9e-05 22.7 0.0 0.24 11.6 0.0 2.9 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.7 EXF83932.1 - 0.00011 21.3 0.1 0.06 12.3 0.0 2.9 3 0 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EXF83932.1 - 0.0002 21.2 0.0 0.18 11.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EXF83932.1 - 0.00032 20.1 0.7 0.57 9.5 0.0 3.5 2 2 2 4 4 4 1 AAA domain IstB_IS21 PF01695.12 EXF83932.1 - 0.00044 19.7 0.2 0.024 14.0 0.0 3.0 4 0 0 4 4 4 1 IstB-like ATP binding protein CDC48_N PF02359.13 EXF83932.1 - 0.0012 18.7 0.0 0.0032 17.3 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain KaiC PF06745.8 EXF83932.1 - 0.0024 17.0 0.1 0.11 11.5 0.1 2.6 2 0 0 2 2 2 1 KaiC Zeta_toxin PF06414.7 EXF83932.1 - 0.0034 16.5 0.0 0.24 10.4 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_11 PF13086.1 EXF83932.1 - 0.0049 16.4 0.0 1 8.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 EXF83932.1 - 0.0076 15.4 0.0 0.48 9.5 0.0 2.4 2 0 0 2 2 2 1 Chromatin associated protein KTI12 NACHT PF05729.7 EXF83932.1 - 0.0081 15.8 0.5 13 5.4 0.0 3.7 3 1 0 3 3 3 0 NACHT domain ABC_tran PF00005.22 EXF83932.1 - 0.0085 16.3 0.1 0.049 13.9 0.0 2.3 2 1 0 2 2 1 1 ABC transporter Sigma54_activat PF00158.21 EXF83932.1 - 0.0085 15.5 0.0 0.63 9.4 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.1 EXF83932.1 - 0.015 15.2 0.0 0.49 10.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain CPT PF07931.7 EXF83932.1 - 0.016 14.8 0.0 0.26 10.8 0.0 2.4 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_24 PF13479.1 EXF83932.1 - 0.026 14.0 0.0 0.71 9.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.6 EXF83932.1 - 0.038 13.5 0.0 0.37 10.3 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EXF83932.1 - 0.042 13.0 0.0 0.73 9.0 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein Parvo_NS1 PF01057.12 EXF83932.1 - 0.049 12.5 0.0 1.3 7.8 0.0 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 EXF83932.1 - 0.14 11.7 0.0 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 EXF83932.1 - 0.16 10.7 0.3 5.2 5.8 0.1 2.8 3 0 0 3 3 3 0 NB-ARC domain Cir_N PF10197.4 EXF83933.1 - 2.9e-05 23.9 2.0 2.9e-05 23.9 1.4 2.8 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR CWC25 PF12542.3 EXF83933.1 - 7.1 7.1 11.0 0.43 11.0 1.4 3.3 3 1 0 3 3 3 0 Pre-mRNA splicing factor FAD_binding_4 PF01565.18 EXF83934.1 - 6.8e-21 74.1 3.3 9.1e-21 73.7 1.4 1.9 1 1 1 2 2 2 1 FAD binding domain BBE PF08031.7 EXF83934.1 - 1.2e-06 28.3 0.1 2.9e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 Berberine and berberine like Glyco_transf_28 PF03033.15 EXF83935.1 - 2.4e-17 62.9 0.1 3.5e-16 59.2 0.0 2.4 1 1 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EXF83935.1 - 0.00083 18.0 0.0 0.0013 17.3 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Sporozoite_P67 PF05642.6 EXF83935.1 - 0.086 10.6 1.6 0.13 10.1 1.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_tran_28_C PF04101.11 EXF83935.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Band_7 PF01145.20 EXF83936.1 - 2.8e-26 92.5 2.4 4.2e-26 91.9 1.7 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family DUF1788 PF08747.6 EXF83936.1 - 0.016 15.1 0.2 0.036 13.9 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1788) Band_7_1 PF13421.1 EXF83936.1 - 0.056 12.9 0.2 0.087 12.3 0.1 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family Sigma70_ner PF04546.8 EXF83938.1 - 0.43 10.1 2.1 0.76 9.3 1.4 1.6 1 0 0 1 1 1 0 Sigma-70, non-essential region BAF1_ABF1 PF04684.8 EXF83938.1 - 1.6 7.4 22.6 0.25 10.1 5.6 2.1 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor KxDL PF10241.4 EXF83939.1 - 2.9e-30 104.0 2.6 4e-30 103.5 1.8 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein DUF2385 PF09539.5 EXF83939.1 - 0.014 15.7 0.5 0.028 14.7 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2385) Mating_C PF12737.2 EXF83939.1 - 0.026 13.4 4.9 1.1 8.0 0.1 2.2 2 1 0 2 2 2 0 C-terminal domain of homeodomain 1 DUF883 PF05957.8 EXF83939.1 - 0.2 12.0 5.9 2.4 8.6 1.1 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) CTP_transf_1 PF01148.15 EXF83940.1 - 4.8e-16 59.2 9.4 3.3e-14 53.1 6.5 2.0 1 1 0 1 1 1 1 Cytidylyltransferase family DEAD PF00270.24 EXF83941.1 - 4.4e-36 123.9 0.0 9.6e-36 122.8 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF83941.1 - 2.4e-19 68.9 0.0 6.4e-19 67.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EXF83941.1 - 8.6e-19 66.8 0.0 1.5e-18 66.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Ank_2 PF12796.2 EXF83942.1 - 9.9e-51 170.0 5.9 1.8e-15 57.0 0.1 7.2 5 1 2 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EXF83942.1 - 5.2e-31 104.9 31.2 4.6e-05 23.0 0.0 12.9 14 1 0 14 14 14 8 Ankyrin repeat Ank_3 PF13606.1 EXF83942.1 - 1.8e-27 92.6 10.7 0.0019 18.2 0.0 11.0 11 0 0 11 11 11 6 Ankyrin repeat Ank_4 PF13637.1 EXF83942.1 - 5.6e-26 90.4 13.2 1.4e-07 31.7 0.0 9.5 6 3 6 12 12 12 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF83942.1 - 1.1e-20 73.1 17.9 0.00023 21.2 0.2 11.4 6 2 5 11 11 11 6 Ankyrin repeats (many copies) Clr5 PF14420.1 EXF83942.1 - 7.4e-07 28.9 0.9 1.7e-06 27.7 0.6 1.6 1 0 0 1 1 1 1 Clr5 domain Ank_2 PF12796.2 EXF83943.1 - 1.5e-39 134.1 1.2 1.4e-13 51.0 0.0 7.7 5 3 3 8 8 8 6 Ankyrin repeats (3 copies) Ank PF00023.25 EXF83943.1 - 6.6e-25 85.6 22.2 5.6e-05 22.7 0.1 9.6 10 0 0 10 10 10 7 Ankyrin repeat Ank_4 PF13637.1 EXF83943.1 - 6.9e-20 71.0 3.1 4.4e-06 27.0 0.0 6.8 6 1 1 7 7 7 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF83943.1 - 1.8e-15 55.4 8.1 0.011 15.8 0.0 10.7 12 0 0 12 12 12 3 Ankyrin repeat Ank_5 PF13857.1 EXF83943.1 - 7.7e-14 51.4 7.7 0.01 16.0 0.0 7.8 6 1 3 9 9 9 3 Ankyrin repeats (many copies) Clr5 PF14420.1 EXF83943.1 - 9e-07 28.6 1.4 2.1e-06 27.5 0.4 2.2 2 0 0 2 2 2 1 Clr5 domain DUF3291 PF11695.3 EXF83943.1 - 0.0036 16.7 0.0 0.0074 15.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3291) RasGEF PF00617.14 EXF83944.1 - 1.2e-49 168.6 0.2 1.9e-49 167.9 0.1 1.4 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EXF83944.1 - 4.1e-12 46.1 0.0 7.8e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 RasGEF N-terminal motif Ribosomal_S2 PF00318.15 EXF83945.1 - 9.5e-44 149.1 0.0 4.9e-23 81.4 0.0 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 Ribosomal_S15 PF00312.17 EXF83946.1 - 5.6e-15 54.8 0.4 1.5e-14 53.5 0.3 1.7 1 0 0 1 1 1 1 Ribosomal protein S15 vATP-synt_AC39 PF01992.11 EXF83947.1 - 1.3e-110 369.7 0.0 1.4e-104 349.8 0.0 2.0 2 0 0 2 2 2 2 ATP synthase (C/AC39) subunit Nop PF01798.13 EXF83948.1 - 3.6e-52 175.6 0.5 8.4e-52 174.4 0.3 1.7 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EXF83948.1 - 8.9e-25 86.2 0.1 1.6e-24 85.4 0.1 1.5 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EXF83948.1 - 1.6e-18 66.5 0.5 1.6e-18 66.5 0.3 3.3 4 0 0 4 4 4 1 NOP5NT (NUC127) domain DUF760 PF05542.6 EXF83948.1 - 0.07 13.3 0.0 0.25 11.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF760) GARS_A PF01071.14 EXF83949.1 - 6.1e-74 247.8 0.0 9.4e-74 247.1 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain APC10 PF03256.11 EXF83949.1 - 5.2e-46 156.6 0.0 1.1e-45 155.6 0.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) GARS_N PF02844.10 EXF83949.1 - 1.1e-32 112.4 0.0 2.2e-32 111.4 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain HET PF06985.6 EXF83949.1 - 7.9e-32 110.3 0.0 1.3e-31 109.5 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) GARS_C PF02843.11 EXF83949.1 - 7.5e-28 96.5 0.0 2.6e-27 94.8 0.0 2.0 2 0 0 2 2 2 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp_4 PF13535.1 EXF83949.1 - 1.4e-07 31.4 0.0 5.9e-07 29.4 0.0 2.1 2 1 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EXF83949.1 - 0.0026 16.5 0.0 0.0053 15.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.9 EXF83949.1 - 0.014 15.2 0.0 0.039 13.8 0.0 1.8 1 0 0 1 1 1 0 ATP-grasp domain CPSase_L_D2 PF02786.12 EXF83949.1 - 0.096 11.9 0.2 0.21 10.8 0.0 1.7 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain NAD_binding_10 PF13460.1 EXF83950.1 - 0.00015 21.8 0.0 0.00016 21.7 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding MFS_1 PF07690.11 EXF83951.1 - 4.2e-26 91.4 49.3 3.9e-16 58.7 21.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_hydro_42 PF02449.10 EXF83952.1 - 8.3e-13 48.1 0.0 1.3e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.14 EXF83952.1 - 8.1e-08 31.9 0.0 0.00028 20.3 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 Glyco_hydro_10 PF00331.15 EXF83952.1 - 0.083 11.9 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Fungal_trans PF04082.13 EXF83953.1 - 4.7e-18 64.9 1.6 8.4e-18 64.1 1.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF83953.1 - 0.00048 19.9 9.9 0.00092 19.0 6.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EXF83954.1 - 5.8e-83 278.9 27.5 6.8e-83 278.7 19.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF83954.1 - 1e-19 70.4 41.6 1.3e-16 60.3 7.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily HLH PF00010.21 EXF83955.1 - 3.1e-16 58.8 0.1 5.8e-16 57.9 0.1 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain ORC6 PF05460.8 EXF83955.1 - 0.019 14.0 13.0 0.031 13.4 9.0 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) TSC22 PF01166.13 EXF83955.1 - 0.09 12.7 0.2 0.09 12.7 0.2 1.9 2 0 0 2 2 2 0 TSC-22/dip/bun family Hid1 PF12722.2 EXF83955.1 - 3.9 5.0 10.7 4.2 4.9 7.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein IncA PF04156.9 EXF83955.1 - 5.8 6.4 15.4 4.6 6.7 0.9 2.1 2 0 0 2 2 2 0 IncA protein p450 PF00067.17 EXF83956.1 - 8.3e-23 80.6 0.0 1e-22 80.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TauD PF02668.11 EXF83957.1 - 3.9e-46 157.8 0.1 6.5e-46 157.0 0.1 1.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family TauD PF02668.11 EXF83958.1 - 1.3e-31 110.2 0.0 5.8e-31 108.1 0.0 1.8 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family CN_hydrolase PF00795.17 EXF83959.1 - 4.1e-27 94.7 0.0 6.4e-27 94.1 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase MFS_1 PF07690.11 EXF83960.1 - 1.6e-34 119.1 31.3 2.4e-34 118.5 21.7 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_2 PF00891.13 EXF83960.1 - 3.6e-26 91.8 0.0 5.3e-26 91.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase PAN_4 PF14295.1 EXF83961.1 - 4.1e-11 42.4 3.5 3.1e-06 26.7 0.3 2.6 2 0 0 2 2 2 2 PAN domain PAN_1 PF00024.21 EXF83961.1 - 1.6e-09 37.3 2.5 0.00011 21.9 0.1 2.3 2 0 0 2 2 2 2 PAN domain MANEC PF07502.9 EXF83961.1 - 2.2e-05 24.3 1.3 0.071 13.1 0.1 2.4 2 0 0 2 2 2 2 MANEC domain PAN_2 PF08276.6 EXF83961.1 - 0.014 15.2 2.7 1.5 8.7 0.1 2.5 2 0 0 2 2 2 0 PAN-like domain Keratin_B2_2 PF13885.1 EXF83961.1 - 9.1 6.0 9.9 22 4.8 1.4 3.1 2 0 0 2 2 2 0 Keratin, high sulfur B2 protein Cu-oxidase_3 PF07732.10 EXF83962.1 - 2e-37 127.5 3.0 2e-37 127.5 2.1 2.1 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EXF83962.1 - 3.3e-37 127.0 0.9 3.3e-37 127.0 0.6 3.1 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EXF83962.1 - 3.4e-33 114.7 3.4 3.3e-32 111.5 0.9 2.5 2 0 0 2 2 2 1 Multicopper oxidase Clr5 PF14420.1 EXF83965.1 - 7.4e-16 57.7 1.8 1.7e-15 56.6 1.2 1.6 1 0 0 1 1 1 1 Clr5 domain TauD PF02668.11 EXF83966.1 - 5.5e-33 114.7 0.1 7.1e-33 114.3 0.1 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Peptidase_S3 PF00944.14 EXF83966.1 - 0.12 11.7 0.0 0.42 10.0 0.0 1.8 2 0 0 2 2 2 0 Alphavirus core protein Peptidase_S10 PF00450.17 EXF83967.1 - 2.1e-84 284.0 2.6 3.2e-84 283.5 1.8 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Zn_clus PF00172.13 EXF83967.1 - 3.1e-06 26.9 8.4 7.9e-06 25.6 5.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF3611 PF12263.3 EXF83967.1 - 0.062 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) DUF1819 PF08849.6 EXF83967.1 - 0.28 10.5 0.2 17 4.7 0.1 2.4 2 0 0 2 2 2 0 Putative inner membrane protein (DUF1819) DUF3984 PF13136.1 EXF83969.1 - 2.4e-73 247.2 19.2 3.3e-73 246.7 13.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3984) Hamartin PF04388.7 EXF83969.1 - 0.89 8.1 6.7 1.1 7.9 4.7 1.1 1 0 0 1 1 1 0 Hamartin protein IKI3 PF04762.7 EXF83970.1 - 0 1072.9 0.0 0 1072.3 0.0 1.2 1 0 0 1 1 1 1 IKI3 family Ras PF00071.17 EXF83972.1 - 1e-55 187.5 0.0 1.2e-55 187.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EXF83972.1 - 1.6e-15 57.6 0.0 2.5e-15 57.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EXF83972.1 - 7.1e-07 28.6 0.0 1.1e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EXF83972.1 - 0.0015 17.7 0.0 0.0022 17.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EXF83972.1 - 0.054 12.6 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region IMS PF00817.15 EXF83973.1 - 1.7e-36 125.2 0.0 3.2e-36 124.3 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EXF83973.1 - 1.7e-08 34.4 0.0 3e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.3 EXF83973.1 - 0.0049 16.8 0.0 0.016 15.2 0.0 1.9 1 0 0 1 1 1 1 IMS family HHH motif ATXN-1_C PF12547.3 EXF83974.1 - 1.5 8.8 8.7 12 5.9 0.1 2.4 2 0 0 2 2 2 0 Capicua transcriptional repressor modulator DUF605 PF04652.11 EXF83975.1 - 5.2 6.3 40.5 3.8 6.8 14.6 2.2 2 0 0 2 2 2 0 Vta1 like Pyridoxal_deC PF00282.14 EXF83976.1 - 1.7e-15 56.3 0.0 2.6e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EXF83976.1 - 0.0019 16.9 0.0 0.0063 15.2 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V Glyco_transf_34 PF05637.7 EXF83977.1 - 4.6e-74 248.9 0.0 5.6e-74 248.6 0.0 1.0 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family DUF273 PF03314.9 EXF83977.1 - 0.00057 19.2 0.0 0.098 11.9 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function, DUF273 RINGv PF12906.2 EXF83978.1 - 3.4e-10 39.8 2.6 1.6e-09 37.6 0.3 2.2 2 0 0 2 2 2 1 RING-variant domain zf-RING_2 PF13639.1 EXF83978.1 - 0.013 15.3 3.4 0.034 13.9 0.6 2.1 2 0 0 2 2 2 0 Ring finger domain Proteasome PF00227.21 EXF83979.1 - 2.8e-51 173.5 0.0 3.5e-27 94.9 0.0 2.2 2 0 0 2 2 2 2 Proteasome subunit Proteasome_A_N PF10584.4 EXF83979.1 - 1.8e-11 43.1 0.3 4e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Ribonuclease_3 PF00636.21 EXF83980.1 - 5.6e-41 139.5 0.0 9.3e-20 71.1 0.0 2.6 2 0 0 2 2 2 2 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EXF83980.1 - 7.6e-24 84.1 0.0 3.2e-10 40.0 0.0 3.7 3 0 0 3 3 3 3 Ribonuclease-III-like DEAD PF00270.24 EXF83980.1 - 4.3e-20 71.8 0.0 8.8e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF83980.1 - 1.1e-17 63.5 0.0 2.8e-17 62.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Dicer_dimer PF03368.9 EXF83980.1 - 1.9e-14 53.2 0.0 3.8e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Dicer dimerisation domain ResIII PF04851.10 EXF83980.1 - 2.1e-10 40.7 0.0 4.6e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EXF83980.1 - 1e-05 24.5 0.0 1.7e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C_2 PF13307.1 EXF83980.1 - 0.0042 17.0 0.0 0.0098 15.8 0.0 1.6 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.10 EXF83980.1 - 0.036 13.4 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 DEAD_2 Bombesin PF02044.12 EXF83984.1 - 0.3 10.5 2.3 0.52 9.8 1.6 1.4 1 0 0 1 1 1 0 Bombesin-like peptide Rgp1 PF08737.5 EXF83985.1 - 5.2e-121 404.6 0.0 2.1e-120 402.6 0.0 1.8 2 0 0 2 2 2 1 Rgp1 Arrestin_N PF00339.24 EXF83985.1 - 0.0039 17.0 0.0 0.0096 15.7 0.0 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain COesterase PF00135.23 EXF83987.1 - 1.5e-28 99.8 0.0 1.9e-28 99.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family ABC_tran PF00005.22 EXF83988.1 - 1.6e-49 167.7 0.0 1.5e-30 106.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EXF83988.1 - 3.6e-20 72.4 33.3 1.2e-15 57.6 7.5 3.9 4 0 0 4 4 4 2 ABC transporter transmembrane region SMC_N PF02463.14 EXF83988.1 - 1.3e-09 37.5 2.4 9.9e-05 21.6 0.3 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EXF83988.1 - 0.0002 21.4 0.8 0.044 13.7 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_25 PF13481.1 EXF83988.1 - 0.00027 20.4 0.1 0.13 11.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_21 PF13304.1 EXF83988.1 - 0.00055 19.9 0.0 1.3 8.9 0.0 3.6 2 1 0 2 2 2 1 AAA domain T2SE PF00437.15 EXF83988.1 - 0.00061 18.7 0.1 0.92 8.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_29 PF13555.1 EXF83988.1 - 0.00073 19.0 1.2 1.1 8.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EXF83988.1 - 0.0014 17.8 0.3 0.87 8.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Miro PF08477.8 EXF83988.1 - 0.01 16.3 0.5 6 7.3 0.1 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_23 PF13476.1 EXF83988.1 - 0.014 15.7 5.6 0.24 11.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 EXF83988.1 - 0.016 15.3 0.1 16 5.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 EXF83988.1 - 0.025 14.5 0.1 0.32 10.9 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.1 EXF83988.1 - 0.026 14.1 0.2 6.5 6.2 0.1 3.0 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.1 EXF83988.1 - 0.08 12.8 0.0 13 5.7 0.0 3.1 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit FAM176 PF14851.1 EXF83988.1 - 0.14 11.8 3.9 0.19 11.4 0.1 2.9 3 0 0 3 3 3 0 FAM176 family DUF87 PF01935.12 EXF83988.1 - 1.4 8.7 7.1 1.3 8.8 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function DUF87 TRAP_alpha PF03896.11 EXF83988.1 - 3.6 6.4 5.4 0.28 10.1 0.2 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit B9-C2 PF07162.6 EXF83989.1 - 0.073 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Ciliary basal body-associated, B9 protein zf-met PF12874.2 EXF83990.1 - 6.6e-06 26.1 1.0 1.4e-05 25.1 0.7 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.4 EXF83990.1 - 0.00061 19.3 0.4 0.0009 18.8 0.3 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PRP4 PF08799.6 EXF83990.1 - 0.051 12.8 0.9 0.095 11.9 0.6 1.5 1 0 0 1 1 1 0 pre-mRNA processing factor 4 (PRP4) like HET PF06985.6 EXF83991.1 - 2.6e-19 69.7 0.0 7.4e-19 68.2 0.0 1.9 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Lipase_GDSL PF00657.17 EXF83994.1 - 3.3e-17 63.1 0.2 4.2e-17 62.7 0.1 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EXF83994.1 - 1.2e-13 51.5 0.1 1.8e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.1 EXF83994.1 - 0.00015 21.5 0.0 0.00023 20.9 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family GFA PF04828.9 EXF83995.1 - 8.8e-12 44.8 0.8 1.5e-11 44.1 0.5 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme RNA_POL_M_15KD PF02150.11 EXF83995.1 - 0.16 11.7 0.0 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 RNA polymerases M/15 Kd subunit Glyco_hydro_42 PF02449.10 EXF83996.1 - 3.8e-10 39.4 0.0 6.2e-10 38.7 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_35 PF01301.14 EXF83996.1 - 2.3e-05 23.9 0.0 0.003 16.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolases family 35 Glyco_hydro_10 PF00331.15 EXF83996.1 - 0.04 12.9 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 10 Fungal_trans PF04082.13 EXF83997.1 - 0.007 15.2 0.0 0.028 13.2 0.0 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain Phosphoprotein PF00922.12 EXF83997.1 - 0.16 11.1 0.2 0.32 10.1 0.0 1.5 2 0 0 2 2 2 0 Vesiculovirus phosphoprotein VCX_VCY PF15231.1 EXF83997.1 - 2.5 8.4 7.2 3.9 7.8 5.0 1.2 1 0 0 1 1 1 0 Variable charge X/Y family Sugar_tr PF00083.19 EXF83998.1 - 2.3e-83 280.2 25.9 2.8e-83 279.9 18.0 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF83998.1 - 6e-20 71.2 38.6 3.6e-14 52.2 9.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily ABC2_membrane_2 PF12679.2 EXF83998.1 - 1.2 7.9 11.4 2.7 6.7 7.9 1.6 1 0 0 1 1 1 0 ABC-2 family transporter protein Pectate_lyase PF03211.8 EXF83999.1 - 4.4e-50 170.0 0.4 6e-50 169.6 0.3 1.1 1 0 0 1 1 1 1 Pectate lyase SKG6 PF08693.5 EXF84000.1 - 0.012 14.8 0.1 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Cu-oxidase_3 PF07732.10 EXF84001.1 - 4e-44 149.1 6.4 1.1e-41 141.2 0.7 4.0 4 0 0 4 4 4 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EXF84001.1 - 2.9e-39 133.7 5.8 1.6e-36 124.8 0.1 3.0 2 1 0 2 2 2 2 Multicopper oxidase Cu-oxidase PF00394.17 EXF84001.1 - 1.1e-38 132.6 0.5 7.2e-36 123.4 0.2 2.5 2 0 0 2 2 2 2 Multicopper oxidase FTR1 PF03239.9 EXF84002.1 - 6.2e-76 255.2 10.4 7.1e-76 255.0 7.2 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF4231 PF14015.1 EXF84002.1 - 0.063 13.2 0.4 0.063 13.2 0.3 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) DUF4401 PF14351.1 EXF84002.1 - 2 7.3 20.8 0.24 10.3 1.3 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4401) NAD_binding_6 PF08030.7 EXF84003.1 - 8.8e-19 67.9 0.0 1.4e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EXF84003.1 - 2.1e-14 53.2 0.0 4.1e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EXF84003.1 - 7.6e-14 51.8 12.2 5.2e-13 49.1 7.1 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_1 PF00175.16 EXF84003.1 - 0.00033 21.1 0.0 0.015 15.8 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain PAP2 PF01569.16 EXF84004.1 - 2.9e-20 72.2 7.3 4.5e-20 71.6 2.0 2.3 2 0 0 2 2 2 2 PAP2 superfamily Glyco_hydro_43 PF04616.9 EXF84005.1 - 3.8e-41 141.0 6.9 5.1e-41 140.6 4.8 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 LysM PF01476.15 EXF84006.1 - 2.8e-19 68.7 0.2 1.6e-09 37.4 0.1 2.2 2 0 0 2 2 2 2 LysM domain Glyco_hydro_16 PF00722.16 EXF84007.1 - 6.8e-15 54.8 0.8 9.6e-15 54.3 0.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Laminin_G_3 PF13385.1 EXF84007.1 - 0.03 14.5 5.4 0.045 13.9 3.7 1.3 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Pyocin_S PF06958.7 EXF84008.1 - 0.79 10.0 4.9 0.55 10.5 0.2 2.6 2 0 0 2 2 2 0 S-type Pyocin AMP-binding PF00501.23 EXF84009.1 - 3.8e-74 249.5 0.0 4.5e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EXF84009.1 - 3.1e-15 56.8 0.1 8.7e-15 55.4 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Sugar_tr PF00083.19 EXF84010.1 - 1.5e-76 257.7 12.2 1.7e-76 257.6 8.5 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF84010.1 - 2.6e-14 52.7 13.9 2.6e-14 52.7 9.6 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EXF84010.1 - 0.0013 17.1 17.1 0.015 13.7 0.6 3.0 3 1 0 3 3 3 2 MFS/sugar transport protein DUF791 PF05631.9 EXF84010.1 - 0.0029 16.3 1.4 0.011 14.4 0.2 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF791) Potex_coat PF06184.6 EXF84010.1 - 0.079 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Potexvirus coat protein NmrA PF05368.8 EXF84011.1 - 4.7e-16 58.7 0.0 5.8e-16 58.4 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF84011.1 - 2.2e-11 44.0 0.0 3.7e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF84011.1 - 3.9e-05 23.2 0.0 6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EXF84011.1 - 0.01 16.1 0.2 0.035 14.4 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Ferric_reduct PF01794.14 EXF84012.1 - 3.1e-15 56.3 5.5 3.1e-15 56.3 3.8 2.6 2 1 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EXF84012.1 - 0.00058 19.6 0.0 0.0015 18.3 0.0 1.6 1 1 0 1 1 1 1 FAD-binding domain NAD_binding_1 PF00175.16 EXF84012.1 - 0.0029 18.1 0.0 0.0079 16.7 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EXF84012.1 - 0.013 15.3 0.0 0.04 13.8 0.0 1.7 1 1 1 2 2 2 0 Ferric reductase NAD binding domain DUF2839 PF10999.3 EXF84012.1 - 0.12 12.3 3.1 0.59 10.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) Pox_A14 PF05767.7 EXF84012.1 - 1.2 9.1 4.4 1.5 8.8 0.5 2.7 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 PhoD PF09423.5 EXF84014.1 - 2e-144 481.5 3.8 7.4e-144 479.6 2.6 1.7 1 1 0 1 1 1 1 PhoD-like phosphatase Macoilin PF09726.4 EXF84015.1 - 2.7 6.1 8.0 4.6 5.4 5.6 1.4 1 0 0 1 1 1 0 Transmembrane protein Methyltransf_23 PF13489.1 EXF84016.1 - 2e-11 43.8 0.0 4.1e-11 42.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF84016.1 - 0.00011 21.8 0.0 0.00016 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Death PF00531.17 EXF84016.1 - 0.029 14.1 0.4 0.27 11.0 0.0 2.6 2 1 1 3 3 3 0 Death domain Methyltransf_18 PF12847.2 EXF84016.1 - 0.048 14.2 0.0 0.13 12.8 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.7 EXF84016.1 - 0.086 13.3 0.0 0.22 12.0 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Oxidored_molyb PF00174.14 EXF84017.1 - 1.1e-45 155.1 0.0 3.1e-45 153.6 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EXF84017.1 - 2.6e-24 85.3 4.1 4.6e-24 84.5 2.9 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Methyltransf_23 PF13489.1 EXF84018.1 - 8.5e-14 51.5 0.0 1.3e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF84018.1 - 0.00057 19.4 0.0 0.0011 18.5 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF84018.1 - 0.00066 20.1 0.0 0.0012 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF84018.1 - 0.0035 17.8 0.0 0.0068 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF84018.1 - 0.015 15.8 0.0 0.026 15.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FAD_binding_4 PF01565.18 EXF84019.1 - 7.2e-18 64.4 0.2 1.2e-17 63.6 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF84019.1 - 0.00055 19.8 0.1 0.0014 18.4 0.0 1.7 1 0 0 1 1 1 1 Berberine and berberine like Aldedh PF00171.17 EXF84020.1 - 3.8e-161 536.5 0.4 4.2e-161 536.3 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EXF84020.1 - 0.0029 16.8 0.1 0.084 12.0 0.0 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1487) BTB PF00651.26 EXF84021.1 - 0.0049 16.8 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain AAA PF00004.24 EXF84022.1 - 3.5e-19 69.3 0.0 6e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EXF84022.1 - 2.5e-05 24.4 0.1 0.00029 21.0 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_17 PF13207.1 EXF84022.1 - 0.00012 22.8 0.6 0.001 19.9 0.0 2.8 2 2 1 3 3 3 1 AAA domain AAA_18 PF13238.1 EXF84022.1 - 0.00013 22.3 0.1 0.0056 16.9 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_5 PF07728.9 EXF84022.1 - 0.00013 21.7 0.0 0.00029 20.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EXF84022.1 - 0.00033 20.6 0.0 0.00073 19.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Zot PF05707.7 EXF84022.1 - 0.00067 19.1 0.1 0.028 13.8 0.0 2.4 1 1 1 2 2 2 1 Zonular occludens toxin (Zot) AAA_19 PF13245.1 EXF84022.1 - 0.0028 17.3 0.4 0.0058 16.3 0.3 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_14 PF13173.1 EXF84022.1 - 0.006 16.4 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EXF84022.1 - 0.0077 16.1 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.1 EXF84022.1 - 0.019 14.3 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EXF84022.1 - 0.033 13.5 0.0 0.069 12.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Zeta_toxin PF06414.7 EXF84022.1 - 0.034 13.2 0.0 0.078 12.0 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.1 EXF84022.1 - 0.036 13.6 0.0 0.064 12.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EXF84022.1 - 0.04 13.4 0.1 0.093 12.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EXF84022.1 - 0.041 13.8 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EXF84022.1 - 0.043 13.7 0.0 0.094 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EXF84022.1 - 0.061 12.1 0.0 0.1 11.3 0.0 1.2 1 0 0 1 1 1 0 ArgK protein PhoH PF02562.11 EXF84022.1 - 0.083 12.1 0.5 1 8.5 0.2 2.7 2 1 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.16 EXF84022.1 - 0.086 11.9 0.1 0.15 11.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI T2SE PF00437.15 EXF84022.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein MFS_1 PF07690.11 EXF84024.1 - 1.8e-32 112.4 34.2 2.3e-32 112.0 23.7 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PTPLA PF04387.9 EXF84025.1 - 1.1e-46 158.3 10.1 1.9e-46 157.4 7.0 1.4 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA DUF21 PF01595.15 EXF84025.1 - 1.5 8.0 12.4 0.06 12.6 3.6 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF21 2-oxoacid_dh PF00198.18 EXF84026.1 - 3.3e-70 235.9 0.0 5.4e-70 235.2 0.0 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EXF84026.1 - 6.3e-19 67.3 4.6 1.1e-18 66.6 3.2 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 EXF84026.1 - 1.7e-08 33.9 7.1 1.4e-07 30.9 1.0 2.2 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.1 EXF84026.1 - 0.00061 19.3 0.8 0.0034 17.0 0.1 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.1 EXF84026.1 - 0.003 17.8 0.8 0.36 11.1 0.0 2.7 1 1 1 2 2 2 1 HlyD family secretion protein GCV_H PF01597.14 EXF84026.1 - 0.0041 16.8 2.5 0.012 15.3 1.5 1.9 1 1 1 2 2 2 1 Glycine cleavage H-protein RnfC_N PF13375.1 EXF84026.1 - 0.0064 16.1 1.8 3 7.6 0.1 3.0 1 1 1 2 2 2 2 RnfC Barrel sandwich hybrid domain DUF2118 PF09891.4 EXF84026.1 - 0.0072 16.0 0.5 0.046 13.4 0.1 2.1 1 1 1 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2118) Suf PF05843.9 EXF84026.1 - 0.48 10.1 4.8 0.74 9.4 3.4 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4551 PF15087.1 EXF84026.1 - 2.9 6.1 5.3 4.4 5.5 3.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) RR_TM4-6 PF06459.7 EXF84026.1 - 4.2 7.1 14.6 6.6 6.5 10.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TP53IP5 PF15331.1 EXF84026.1 - 6 6.7 14.0 8 6.3 8.9 1.7 1 1 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Transket_pyr PF02779.19 EXF84027.1 - 3e-59 199.4 0.0 4.5e-59 198.9 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EXF84027.1 - 3.1e-50 170.6 0.0 5.6e-50 169.7 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Amino_oxidase PF01593.19 EXF84028.1 - 3.3e-21 75.8 0.2 7.5e-15 54.9 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EXF84028.1 - 8.8e-05 22.4 0.0 0.00019 21.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DUF3328 PF11807.3 EXF84029.1 - 1.8e-35 122.5 2.2 5.1e-35 121.1 0.4 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3328) RNase_T PF00929.19 EXF84031.1 - 3e-12 47.1 0.0 4.4e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EXF84031.1 - 0.0055 16.1 0.0 0.0095 15.4 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Herpes_UL49_2 PF04823.7 EXF84031.1 - 0.027 14.4 0.1 0.063 13.2 0.0 1.6 1 0 0 1 1 1 0 Herpesvirus UL49 tegument protein zf-C2H2 PF00096.21 EXF84031.1 - 0.057 13.7 0.9 0.16 12.3 0.3 2.0 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF84031.1 - 0.11 12.8 0.7 0.32 11.4 0.5 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger Oxysterol_BP PF01237.13 EXF84032.1 - 3.1e-69 233.1 0.0 4e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein Peptidase_S10 PF00450.17 EXF84034.1 - 2.3e-82 277.4 0.1 4.2e-82 276.5 0.0 1.4 1 1 0 1 1 1 1 Serine carboxypeptidase CFEM PF05730.6 EXF84035.1 - 0.0013 18.5 11.2 0.0028 17.4 7.7 1.5 1 0 0 1 1 1 1 CFEM domain MFS_1 PF07690.11 EXF84036.1 - 3.9e-22 78.4 32.6 3.9e-22 78.4 22.6 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EXF84036.1 - 8.1e-07 27.6 5.7 1.4e-06 26.7 3.9 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EXF84036.1 - 1.8e-05 23.5 8.6 1.8e-05 23.5 6.0 3.0 2 2 0 2 2 2 1 Sugar (and other) transporter Flavi_NS4A PF01350.12 EXF84036.1 - 5.4 6.5 7.9 2.3 7.7 0.0 3.6 4 1 0 4 4 4 0 Flavivirus non-structural protein NS4A Zn_clus PF00172.13 EXF84037.1 - 3.6e-06 26.7 12.4 6.9e-06 25.8 8.6 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF84037.1 - 1.1e-05 24.2 0.1 2.2e-05 23.2 0.1 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 EXF84038.1 - 4.5e-51 173.5 7.3 7e-51 172.8 5.1 1.2 1 0 0 1 1 1 1 RTA1 like protein Syndecan PF01034.15 EXF84038.1 - 0.075 12.6 1.0 0.19 11.3 0.0 2.2 2 0 0 2 2 2 0 Syndecan domain DUF4603 PF15376.1 EXF84039.1 - 1 6.4 4.0 1 6.4 2.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) SKG6 PF08693.5 EXF84040.1 - 0.001 18.3 0.6 0.002 17.4 0.4 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EXF84040.1 - 0.0038 16.7 0.0 0.0057 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Mid2 PF04478.7 EXF84040.1 - 0.026 13.9 1.2 0.04 13.3 0.3 1.6 2 0 0 2 2 2 0 Mid2 like cell wall stress sensor Cyt-b5 PF00173.23 EXF84041.1 - 8.5e-12 44.7 0.0 1.3e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glyco_hydro_61 PF03443.9 EXF84041.1 - 4.3e-06 26.7 0.0 5.6e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Scytalone_dh PF02982.9 EXF84042.1 - 1.1e-97 324.1 1.3 1.2e-97 323.9 0.9 1.0 1 0 0 1 1 1 1 Scytalone dehydratase SnoaL_4 PF13577.1 EXF84042.1 - 1.4e-07 31.4 0.2 1.9e-07 31.0 0.1 1.2 1 0 0 1 1 1 1 SnoaL-like domain HET PF06985.6 EXF84043.1 - 1e-21 77.5 2.4 2.9e-17 63.1 0.1 2.6 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) Glyco_hydro_62 PF03664.8 EXF84044.1 - 2.8e-150 498.8 14.2 3.3e-150 498.6 9.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 62 MIP PF00230.15 EXF84045.1 - 1.8e-45 155.1 8.2 2.1e-45 154.9 5.7 1.1 1 0 0 1 1 1 1 Major intrinsic protein Asp PF00026.18 EXF84046.1 - 4.3e-54 183.8 0.0 5.7e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EXF84046.1 - 5e-08 33.0 1.4 8.3e-08 32.3 1.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EXF84046.1 - 0.00051 20.4 0.2 7.5 7.1 0.0 3.4 2 1 0 2 2 2 2 Aspartyl protease Kelch_5 PF13854.1 EXF84047.1 - 6.7e-15 54.6 5.0 9.8e-12 44.5 0.1 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 EXF84047.1 - 9.1e-06 25.3 19.6 0.015 15.0 0.1 5.6 5 0 0 5 5 5 2 Galactose oxidase, central domain Gly-zipper_Omp PF13488.1 EXF84047.1 - 0.00011 21.7 0.7 0.00032 20.2 0.5 1.7 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_OmpA PF13436.1 EXF84047.1 - 0.0023 17.5 0.9 0.005 16.5 0.6 1.5 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 EXF84047.1 - 0.0035 16.8 4.4 0.01 15.3 3.1 1.7 1 0 0 1 1 1 1 YMGG-like Gly-zipper DUF456 PF04306.8 EXF84047.1 - 0.0064 16.5 0.3 0.011 15.7 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF456) CD99L2 PF12301.3 EXF84047.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 CD99 antigen like protein 2 Rick_17kDa_Anti PF05433.10 EXF84047.1 - 0.013 15.1 4.4 0.043 13.4 3.1 1.8 1 0 0 1 1 1 0 Glycine zipper 2TM domain SKG6 PF08693.5 EXF84047.1 - 0.049 12.9 1.9 0.092 12.0 1.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4366 PF14283.1 EXF84047.1 - 0.055 12.8 0.1 0.093 12.1 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Herpes_gE PF02480.11 EXF84047.1 - 0.069 11.4 0.0 0.11 10.7 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Kelch_2 PF07646.10 EXF84047.1 - 0.084 12.6 4.0 1.1 9.1 0.1 3.9 3 0 0 3 3 3 0 Kelch motif Kelch_3 PF13415.1 EXF84047.1 - 0.44 10.7 20.7 0.4 10.9 0.1 5.6 6 1 0 6 6 6 0 Galactose oxidase, central domain Kelch_1 PF01344.20 EXF84047.1 - 1.6 8.3 8.5 30 4.2 0.1 4.4 4 0 0 4 4 4 0 Kelch motif Bacteriocin_IIc PF10439.4 EXF84047.1 - 6.3 7.0 8.4 1 9.5 2.2 2.4 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide UDPGT PF00201.13 EXF84048.1 - 0.0002 20.0 0.0 0.0003 19.4 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EXF84048.1 - 0.091 12.4 0.0 0.21 11.2 0.0 1.7 1 1 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Ank_2 PF12796.2 EXF84049.1 - 8.1e-83 272.8 2.8 5.4e-17 61.9 0.3 6.9 1 1 3 6 6 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EXF84049.1 - 1.1e-80 261.6 1.7 2.3e-09 36.5 0.0 13.4 13 0 0 13 13 13 11 Ankyrin repeat Ank_4 PF13637.1 EXF84049.1 - 1.7e-59 197.2 15.9 1.4e-09 38.1 0.0 10.2 4 3 6 10 10 10 10 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF84049.1 - 1.4e-54 180.8 8.9 1.1e-10 41.3 0.2 9.9 3 2 6 10 10 10 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF84049.1 - 5.7e-52 168.4 6.5 2.6e-05 24.0 0.0 13.0 13 0 0 13 13 13 10 Ankyrin repeat NACHT PF05729.7 EXF84049.1 - 0.017 14.7 0.0 0.042 13.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Glyco_hydro_61 PF03443.9 EXF84051.1 - 6.9e-60 202.5 0.1 1.1e-59 201.9 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EXF84051.1 - 4.1e-10 39.1 13.9 4.1e-10 39.1 9.6 3.9 2 2 1 3 3 3 1 Fungal cellulose binding domain NPCBM_assoc PF10633.4 EXF84051.1 - 0.046 13.7 0.0 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase Cellulase PF00150.13 EXF84052.1 - 1.5e-22 80.1 4.3 2e-22 79.7 3.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_2_C PF02836.12 EXF84052.1 - 9.5e-07 27.9 0.0 2.6e-06 26.5 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Cellulase-like PF12876.2 EXF84052.1 - 1.2e-06 28.8 0.0 2.8e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Sugar-binding cellulase-like Glyco_hydro_42 PF02449.10 EXF84052.1 - 0.00034 19.8 0.8 0.001 18.2 0.0 2.0 3 0 0 3 3 3 1 Beta-galactosidase Glyco_hydro_10 PF00331.15 EXF84052.1 - 0.047 12.7 0.1 0.1 11.6 0.0 1.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 10 Solute_trans_a PF03619.11 EXF84053.1 - 6e-43 147.1 17.0 5.9e-42 143.8 11.8 2.0 1 1 0 1 1 1 1 Organic solute transporter Ostalpha Git3_C PF11970.3 EXF84053.1 - 0.63 9.8 5.2 0.49 10.2 1.3 2.5 2 0 0 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 C-term FA_hydroxylase PF04116.8 EXF84056.1 - 4.3e-15 56.1 21.3 4.3e-15 56.1 14.8 2.0 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Fungal_trans_2 PF11951.3 EXF84057.1 - 7.5e-17 60.9 3.2 3e-16 59.0 2.2 1.8 1 1 0 1 1 1 1 Fungal specific transcription factor domain Acetyltransf_7 PF13508.1 EXF84057.1 - 7.9e-06 25.9 0.0 1.9e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EXF84057.1 - 0.0001 22.2 0.0 0.00022 21.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 EXF84057.1 - 0.0057 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 EXF84057.1 - 0.017 15.2 0.0 0.13 12.4 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EXF84057.1 - 0.074 12.9 0.1 7.1 6.4 0.0 3.0 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain DAO PF01266.19 EXF84058.1 - 4.9e-39 134.2 1.0 6.3e-39 133.8 0.7 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF84058.1 - 0.0016 18.4 0.9 0.0032 17.4 0.6 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EXF84058.1 - 0.011 15.5 0.1 0.027 14.2 0.1 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EXF84058.1 - 0.083 13.3 0.1 0.21 11.9 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF84058.1 - 0.097 12.7 0.0 4.5 7.2 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AA_permease_2 PF13520.1 EXF84059.1 - 8.9e-42 143.1 48.0 1.1e-41 142.8 33.3 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF84059.1 - 4.3e-14 51.7 41.3 5.5e-14 51.3 28.7 1.0 1 0 0 1 1 1 1 Amino acid permease Cupin_1 PF00190.17 EXF84060.1 - 2.1e-23 82.3 0.0 3.8e-12 45.8 0.0 2.2 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.6 EXF84060.1 - 6.7e-20 70.3 0.1 7.5e-12 44.5 0.1 2.4 2 0 0 2 2 2 2 Cupin domain Cupin_3 PF05899.7 EXF84060.1 - 7.3e-09 34.9 0.1 2.5e-05 23.5 0.1 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) MannoseP_isomer PF01050.13 EXF84060.1 - 1.2e-05 24.9 0.0 0.0027 17.3 0.0 2.2 2 0 0 2 2 2 2 Mannose-6-phosphate isomerase AraC_binding PF02311.14 EXF84060.1 - 0.00018 21.2 0.0 0.077 12.6 0.0 2.6 3 0 0 3 3 3 2 AraC-like ligand binding domain 3-HAO PF06052.7 EXF84060.1 - 0.00054 19.4 0.0 0.0024 17.2 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyanthranilic acid dioxygenase FdtA PF05523.6 EXF84060.1 - 0.0018 17.7 0.0 0.11 12.0 0.0 2.3 2 0 0 2 2 2 1 WxcM-like, C-terminal Cupin_6 PF12852.2 EXF84060.1 - 0.0021 17.7 0.0 0.11 12.0 0.0 2.3 2 0 0 2 2 2 1 Cupin TIL PF01826.12 EXF84061.1 - 0.71 10.0 11.2 0.41 10.8 6.6 1.4 2 0 0 2 2 2 0 Trypsin Inhibitor like cysteine rich domain DUF3543 PF12063.3 EXF84063.1 - 2.4e-87 292.1 0.3 3.4e-87 291.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase PF00069.20 EXF84063.1 - 4e-60 203.1 0.0 9.7e-60 201.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF84063.1 - 4.9e-42 143.7 0.0 9.1e-42 142.9 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase MIT PF04212.13 EXF84063.1 - 0.00032 20.5 0.2 0.22 11.4 0.0 2.6 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain Dynamitin PF04912.9 EXF84063.1 - 0.019 13.7 0.8 0.03 13.1 0.5 1.2 1 0 0 1 1 1 0 Dynamitin Fmp27_WPPW PF10359.4 EXF84063.1 - 0.096 11.0 0.0 0.16 10.3 0.0 1.3 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Pox_ser-thr_kin PF05445.6 EXF84063.1 - 0.2 10.3 0.0 0.3 9.8 0.0 1.2 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Peptidase_M1 PF01433.15 EXF84065.1 - 5.4e-73 246.3 0.0 7.2e-73 245.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EXF84065.1 - 3e-43 146.8 0.0 6e-43 145.8 0.0 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EXF84065.1 - 6.6e-18 64.9 0.1 1.2e-17 64.1 0.1 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Svf1 PF08622.5 EXF84065.1 - 0.0059 15.6 0.0 0.0089 15.0 0.0 1.2 1 0 0 1 1 1 1 Svf1-like Peptidase_M61 PF05299.7 EXF84065.1 - 0.16 11.9 2.3 1.1 9.3 1.6 2.3 1 1 0 1 1 1 0 M61 glycyl aminopeptidase DUF1580 PF07618.6 EXF84066.1 - 0.21 10.9 1.4 5.8 6.3 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1580) Ank_2 PF12796.2 EXF84067.1 - 2.3e-57 191.2 3.8 4.5e-18 65.3 0.1 6.2 2 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 EXF84067.1 - 1.5e-43 144.4 15.6 1.8e-05 24.3 0.0 11.4 12 0 0 12 12 12 9 Ankyrin repeat Ank_5 PF13857.1 EXF84067.1 - 3.2e-35 119.3 9.5 2.1e-07 30.9 0.0 7.7 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_4 PF13637.1 EXF84067.1 - 2.2e-29 101.2 4.3 0.00012 22.5 0.0 7.9 3 1 3 7 7 7 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF84067.1 - 5.5e-25 84.9 8.2 0.014 15.5 0.0 11.5 13 0 0 13 13 11 5 Ankyrin repeat AAA_22 PF13401.1 EXF84067.1 - 7.9e-09 35.7 0.4 5.9e-08 32.9 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EXF84067.1 - 8.5e-09 35.6 0.3 8.5e-09 35.6 0.2 2.2 2 0 0 2 2 2 1 AAA ATPase domain NACHT PF05729.7 EXF84067.1 - 2e-07 30.8 0.2 4.4e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 EXF84067.1 - 4.7e-06 25.6 0.0 8.8e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA PF00004.24 EXF84067.1 - 0.011 15.8 0.0 0.04 14.1 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EXF84067.1 - 0.015 15.0 0.1 0.07 12.8 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain Arch_ATPase PF01637.13 EXF84067.1 - 0.017 14.8 0.0 0.036 13.7 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase DUF2075 PF09848.4 EXF84067.1 - 0.027 13.4 0.0 0.043 12.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 EXF84067.1 - 0.061 14.1 0.0 0.42 11.4 0.0 2.6 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.1 EXF84067.1 - 0.07 12.5 0.0 0.21 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EXF84067.1 - 0.3 10.1 0.0 0.93 8.5 0.0 1.7 1 1 0 1 1 1 0 KaiC zf-Di19 PF05605.7 EXF84067.1 - 2.3 8.3 5.3 23 5.2 0.0 2.9 3 0 0 3 3 2 0 Drought induced 19 protein (Di19), zinc-binding DAO PF01266.19 EXF84068.1 - 1.8e-51 175.1 0.4 2.1e-51 174.9 0.3 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF84068.1 - 2.9e-07 30.5 0.0 0.00052 19.9 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF84068.1 - 2.7e-06 27.2 0.2 0.031 14.0 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EXF84068.1 - 5.3e-06 26.3 0.0 1.4e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EXF84068.1 - 0.00022 21.3 0.1 0.17 11.8 0.0 2.3 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF84068.1 - 0.00075 18.4 0.2 0.0023 16.8 0.1 1.7 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 EXF84068.1 - 0.0019 16.7 0.0 0.025 13.0 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EXF84068.1 - 0.0025 16.7 0.1 0.41 9.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.22 EXF84068.1 - 0.01 16.2 0.0 0.04 14.3 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EXF84068.1 - 0.011 14.7 0.0 0.023 13.7 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EXF84068.1 - 0.026 13.4 0.0 0.09 11.6 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Thi4 PF01946.12 EXF84068.1 - 0.046 12.8 0.0 0.08 12.0 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Shikimate_DH PF01488.15 EXF84068.1 - 0.055 13.5 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ICL PF00463.16 EXF84069.1 - 1.7e-285 947.2 1.7 1.9e-285 947.0 1.2 1.0 1 0 0 1 1 1 1 Isocitrate lyase family PEP_mutase PF13714.1 EXF84069.1 - 2.1e-12 46.7 0.1 7.5e-12 44.9 0.0 1.9 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Trehalase PF01204.13 EXF84070.1 - 1.3e-194 647.6 0.0 1.6e-194 647.3 0.0 1.1 1 0 0 1 1 1 1 Trehalase Trehalase_Ca-bi PF07492.6 EXF84070.1 - 2.4e-16 58.7 0.1 4.3e-16 57.9 0.0 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain RHH_4 PF13467.1 EXF84070.1 - 0.11 12.4 0.0 5.2 7.0 0.0 2.5 2 0 0 2 2 2 0 Ribbon-helix-helix domain DUF1279 PF06916.8 EXF84071.1 - 1.1e-28 99.3 0.2 4.8e-28 97.2 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) PNGaseA PF12222.3 EXF84073.1 - 3.8e-121 404.9 0.1 1.9e-82 277.4 0.3 2.1 2 0 0 2 2 2 2 Peptide N-acetyl-beta-D-glucosaminyl asparaginase amidase A FANCI_HD1 PF14679.1 EXF84074.1 - 0.017 14.8 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 FANCI helical domain 1 P5CR_dimer PF14748.1 EXF84075.1 - 3.4e-38 129.9 0.1 3.4e-38 129.9 0.1 2.8 4 1 0 4 4 4 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EXF84075.1 - 1.9e-18 66.6 3.2 5.7e-18 65.1 2.2 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EXF84075.1 - 0.00098 18.8 7.8 0.013 15.2 3.8 2.7 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 EXF84075.1 - 0.0029 17.4 0.7 0.0058 16.4 0.5 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase CoA_binding PF02629.14 EXF84075.1 - 0.0088 16.5 2.1 0.026 15.0 1.5 1.9 1 0 0 1 1 1 1 CoA binding domain Shikimate_DH PF01488.15 EXF84075.1 - 0.036 14.1 0.2 0.1 12.7 0.1 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NMT1_2 PF13379.1 EXF84075.1 - 0.044 13.1 0.8 0.64 9.3 0.0 2.4 2 1 0 3 3 3 0 NMT1-like family PhyH PF05721.8 EXF84077.1 - 5.9e-20 72.2 0.0 7.9e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Amidohydro_5 PF13594.1 EXF84078.1 - 3e-14 52.5 0.0 2.4e-13 49.7 0.0 2.6 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 EXF84078.1 - 3.3e-14 53.2 0.1 2.2e-13 50.6 0.1 2.0 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EXF84078.1 - 1.4e-06 28.5 0.9 0.011 15.7 0.1 2.7 3 1 0 3 3 3 2 Amidohydrolase Amidohydro_3 PF07969.6 EXF84078.1 - 0.00027 20.2 0.1 0.38 9.9 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Hpr_kinase_C PF07475.7 EXF84078.1 - 0.063 12.5 0.2 0.22 10.8 0.0 1.8 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain FAD_binding_3 PF01494.14 EXF84079.1 - 0.025 13.6 0.5 0.038 13.0 0.3 1.2 1 0 0 1 1 1 0 FAD binding domain DUF1013 PF06242.6 EXF84079.1 - 0.12 12.3 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1013) Methyltransf_23 PF13489.1 EXF84081.1 - 3.2e-18 65.9 0.0 5.8e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF84081.1 - 2.6e-10 40.0 0.0 4.6e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EXF84081.1 - 6.5e-10 39.5 0.0 1.7e-08 35.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF84081.1 - 2.2e-08 34.4 0.0 9.1e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF84081.1 - 4.3e-07 30.3 0.0 1.2e-05 25.7 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF84081.1 - 0.00012 22.4 0.0 0.00052 20.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF84081.1 - 0.00023 21.1 0.0 0.049 13.6 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF84081.1 - 0.0019 17.6 0.0 0.0042 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EXF84081.1 - 0.0063 15.5 0.0 0.12 11.4 0.0 2.5 2 1 1 3 3 3 1 Putative methyltransferase PrmA PF06325.8 EXF84081.1 - 0.013 14.6 0.0 0.034 13.2 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EXF84081.1 - 0.014 14.5 0.0 0.53 9.3 0.0 2.3 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EXF84081.1 - 0.14 12.1 0.0 0.43 10.5 0.0 1.8 1 1 1 2 2 2 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EXF84081.1 - 0.17 11.2 0.0 0.27 10.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FMN_dh PF01070.13 EXF84082.1 - 5.5e-96 321.5 1.1 1.8e-94 316.4 0.7 2.0 1 1 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EXF84082.1 - 7.8e-24 83.2 0.0 9.8e-23 79.7 0.0 2.2 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EXF84082.1 - 7.4e-07 28.4 0.1 1.2e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EXF84082.1 - 9.8e-06 24.6 0.4 0.0013 17.6 0.1 2.2 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EXF84082.1 - 0.0042 16.2 0.6 0.0078 15.4 0.4 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 EXF84082.1 - 0.017 14.3 0.1 0.038 13.2 0.0 1.6 1 0 0 1 1 1 0 Histidine biosynthesis protein ThiG PF05690.9 EXF84082.1 - 0.034 13.2 0.1 1.4 7.9 0.1 2.4 1 1 0 2 2 2 0 Thiazole biosynthesis protein ThiG Borrelia_P83 PF05262.6 EXF84083.1 - 0.49 8.5 9.8 0.62 8.2 6.8 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Marek_SORF3 PF07153.6 EXF84083.1 - 2.9 6.4 5.1 2.8 6.5 1.4 2.0 1 1 1 2 2 2 0 Marek's disease-like virus SORF3 protein ATP-synt_B PF00430.13 EXF84083.1 - 5.9 6.6 21.8 0.35 10.6 0.7 2.1 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) TraK PF06586.6 EXF84084.1 - 0.14 11.2 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 TraK protein Sugar_tr PF00083.19 EXF84085.1 - 2.5e-94 316.4 22.5 2.9e-94 316.2 15.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF84085.1 - 1.1e-40 139.4 43.4 7e-35 120.3 12.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily HET PF06985.6 EXF84086.1 - 1.9e-21 76.6 0.0 5e-21 75.3 0.0 1.7 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DEAD PF00270.24 EXF84087.1 - 2.1e-41 141.2 0.1 4.1e-41 140.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF84087.1 - 3.4e-23 81.3 0.0 7.5e-14 51.3 0.0 2.6 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EXF84087.1 - 1.4e-06 28.3 0.0 5.9e-06 26.2 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EXF84087.1 - 0.025 14.7 0.0 0.1 12.7 0.0 2.0 1 1 0 1 1 1 0 AAA domain Methyltransf_23 PF13489.1 EXF84088.1 - 3.8e-12 46.2 0.0 5.6e-12 45.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF84088.1 - 1.9e-10 41.1 0.0 2.9e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF84088.1 - 2e-08 34.8 0.0 3.2e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF84088.1 - 2.1e-07 30.9 0.1 5.2e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF84088.1 - 3.2e-07 30.7 0.0 6.2e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF84088.1 - 7.9e-07 28.7 0.0 1.2e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF84088.1 - 2.9e-05 24.3 0.0 4.6e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF84088.1 - 0.078 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Pox_MCEL PF03291.11 EXF84088.1 - 0.22 10.3 0.0 0.38 9.5 0.0 1.4 1 1 0 1 1 1 0 mRNA capping enzyme Sugar_tr PF00083.19 EXF84089.1 - 7.4e-81 272.0 22.2 8.4e-81 271.8 15.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF84089.1 - 3.9e-29 101.4 39.3 2.9e-19 69.0 12.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EXF84089.1 - 0.0019 17.9 0.3 0.51 10.1 0.0 3.0 2 0 0 2 2 2 2 MFS_1 like family Zn_clus PF00172.13 EXF84090.1 - 7.2e-09 35.4 10.8 1.6e-08 34.2 7.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AflR PF08493.5 EXF84090.1 - 2.2e-08 33.5 5.2 1.2e-07 31.0 3.4 2.5 1 1 0 1 1 1 1 Aflatoxin regulatory protein Methyltransf_2 PF00891.13 EXF84091.1 - 1.3e-29 103.1 0.0 2.4e-29 102.2 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EXF84091.1 - 0.0002 21.8 0.0 0.00054 20.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF84091.1 - 0.0039 17.5 0.0 0.014 15.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EXF84091.1 - 0.0062 15.9 0.0 0.017 14.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EXF84091.1 - 0.058 12.9 0.0 0.15 11.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain PG_binding_1 PF01471.13 EXF84091.1 - 0.14 12.1 0.0 0.37 10.7 0.0 1.6 1 0 0 1 1 1 0 Putative peptidoglycan binding domain DUF481 PF04338.7 EXF84091.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF481 Methyltransf_2 PF00891.13 EXF84092.1 - 2.2e-42 144.9 0.1 3.3e-42 144.3 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase FAD_binding_3 PF01494.14 EXF84092.1 - 5.6e-17 61.8 0.1 1.7e-05 24.0 0.1 3.2 3 0 0 3 3 3 3 FAD binding domain NAD_binding_8 PF13450.1 EXF84092.1 - 0.00036 20.5 0.0 0.0011 18.9 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Methyltransf_18 PF12847.2 EXF84092.1 - 0.0038 17.7 0.0 0.0099 16.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 EXF84092.1 - 0.041 13.4 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) PCMT PF01135.14 EXF84092.1 - 0.071 12.6 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) ketoacyl-synt PF00109.21 EXF84093.1 - 5.1e-72 242.4 0.2 1e-71 241.4 0.1 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EXF84093.1 - 6.9e-44 150.4 1.0 2.8e-43 148.4 0.4 2.1 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EXF84093.1 - 7e-32 109.7 5.5 9.3e-32 109.3 2.6 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thioesterase PF00975.15 EXF84093.1 - 4.7e-28 98.9 0.0 1.5e-27 97.3 0.0 2.0 1 0 0 1 1 1 1 Thioesterase domain PS-DH PF14765.1 EXF84093.1 - 6.5e-14 51.7 0.0 1.6e-13 50.4 0.0 1.6 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 EXF84093.1 - 5.5e-09 36.1 4.6 1.9e-08 34.4 0.5 3.1 3 0 0 3 3 3 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EXF84093.1 - 1.1e-06 27.8 0.0 3.1e-06 26.3 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Abhydrolase_6 PF12697.2 EXF84093.1 - 1.5e-06 28.2 3.7 0.00071 19.5 0.0 3.3 3 1 0 3 3 3 2 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF84093.1 - 0.00011 21.9 0.1 0.046 13.4 0.0 3.3 3 0 0 3 3 3 1 Alpha/beta hydrolase family FAD_binding_4 PF01565.18 EXF84094.1 - 9.8e-23 80.1 0.1 1.7e-22 79.3 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain NmrA PF05368.8 EXF84095.1 - 3e-15 56.1 0.0 9.4e-15 54.4 0.0 1.7 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF84095.1 - 3.9e-15 56.3 0.1 5.6e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF84095.1 - 0.0001 21.8 0.0 0.00021 20.8 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EXF84095.1 - 0.0019 18.5 0.0 0.0043 17.4 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.1 EXF84095.1 - 0.002 18.3 0.0 0.0053 17.0 0.0 1.7 2 0 0 2 2 2 1 Putative NAD(P)-binding DFP PF04127.10 EXF84095.1 - 0.0024 17.5 0.4 0.031 13.9 0.0 2.4 2 1 0 2 2 2 1 DNA / pantothenate metabolism flavoprotein NAD_binding_2 PF03446.10 EXF84095.1 - 0.0034 17.2 0.0 0.018 14.9 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Saccharop_dh PF03435.13 EXF84095.1 - 0.0068 15.4 0.0 0.021 13.7 0.0 1.7 2 0 0 2 2 2 1 Saccharopine dehydrogenase 2-Hacid_dh_C PF02826.14 EXF84095.1 - 0.065 12.3 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EXF84095.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain BT1 PF03092.11 EXF84095.1 - 0.11 11.2 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 BT1 family Cu-oxidase_3 PF07732.10 EXF84096.1 - 3.3e-38 130.0 2.6 6.9e-38 129.0 0.1 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EXF84096.1 - 3.3e-28 97.9 6.9 1.1e-20 73.5 0.1 4.2 3 1 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.17 EXF84096.1 - 4.8e-16 59.0 0.1 9.6e-14 51.5 0.0 2.4 2 0 0 2 2 2 2 Multicopper oxidase ThiS PF02597.15 EXF84096.1 - 0.11 12.9 0.0 0.53 10.7 0.0 2.0 2 0 0 2 2 2 0 ThiS family Fasciclin PF02469.17 EXF84097.1 - 3e-30 104.8 0.0 6.5e-17 61.7 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain CcmD PF04995.9 EXF84097.1 - 0.0075 15.9 0.7 0.023 14.4 0.5 1.8 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) MFS_1 PF07690.11 EXF84098.1 - 6.4e-40 136.9 28.9 7.9e-40 136.6 20.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF84098.1 - 1.8e-15 56.5 11.5 3.1e-15 55.7 8.0 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 EXF84098.1 - 0.054 11.5 5.3 2 6.3 0.9 2.8 3 0 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF1129 PF06570.6 EXF84098.1 - 0.56 9.4 6.8 0.053 12.8 0.2 2.5 2 2 1 3 3 3 0 Protein of unknown function (DUF1129) EthD PF07110.6 EXF84100.1 - 6.3e-10 39.8 0.1 7.6e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 EthD domain adh_short PF00106.20 EXF84101.1 - 1.2e-19 70.7 0.0 4.2e-19 69.0 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EXF84101.1 - 4.4e-10 39.5 0.0 6.6e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF84101.1 - 2.4e-08 34.0 0.1 4.8e-08 33.0 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EXF84101.1 - 0.011 15.7 0.1 0.033 14.1 0.1 1.8 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EXF84101.1 - 0.11 11.9 0.1 0.14 11.6 0.1 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EXF84103.1 - 4.1e-18 65.8 0.3 6.5e-18 65.1 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF84103.1 - 9.3e-08 31.9 0.1 1.5e-07 31.2 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF84103.1 - 4.5e-07 29.5 0.1 6.9e-07 28.9 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EXF84103.1 - 6.4e-07 29.3 0.0 1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EXF84103.1 - 0.00051 20.0 0.3 0.0014 18.6 0.2 1.7 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EXF84103.1 - 0.03 13.5 0.2 0.046 12.9 0.1 1.3 1 0 0 1 1 1 0 NmrA-like family eRF1_3 PF03465.10 EXF84103.1 - 0.071 13.3 0.1 0.33 11.2 0.0 2.1 2 0 0 2 2 2 0 eRF1 domain 3 ACT_7 PF13840.1 EXF84103.1 - 0.082 12.4 0.2 10 5.7 0.0 2.4 2 0 0 2 2 2 0 ACT domain MFS_1 PF07690.11 EXF84104.1 - 3.5e-37 127.9 44.6 1.4e-35 122.6 31.9 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EXF84104.1 - 7.3e-11 40.9 26.3 1e-10 40.4 18.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EXF84104.1 - 1.5e-09 36.9 33.4 9.9e-07 27.6 13.1 2.8 3 1 0 3 3 3 2 Sugar (and other) transporter PgaD PF13994.1 EXF84104.1 - 0.03 13.8 0.2 10 5.6 0.0 3.4 3 0 0 3 3 3 0 PgaD-like protein Ferric_reduct PF01794.14 EXF84105.1 - 1.3e-16 60.8 11.7 1.3e-16 60.8 8.1 2.4 3 0 0 3 3 3 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.7 EXF84105.1 - 0.0055 16.5 0.0 0.015 15.1 0.0 1.7 1 0 0 1 1 1 1 FAD-binding domain B_lectin PF01453.19 EXF84106.1 - 0.00017 21.4 0.1 0.013 15.3 0.1 2.3 1 1 1 2 2 2 2 D-mannose binding lectin XPG_I_2 PF12813.2 EXF84107.1 - 6.4e-42 143.7 0.0 1.6e-41 142.4 0.0 1.6 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 EXF84107.1 - 0.14 12.2 0.0 0.42 10.7 0.0 1.8 1 0 0 1 1 1 0 XPG I-region Pribosyltran_N PF13793.1 EXF84108.1 - 5e-42 142.2 0.2 5.6e-40 135.6 0.0 2.3 2 0 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EXF84108.1 - 1e-34 119.8 0.0 5.4e-29 101.2 0.0 2.3 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EXF84108.1 - 3.8e-05 23.4 0.2 0.0041 16.8 0.0 2.8 3 0 0 3 3 3 2 Phosphoribosyl transferase domain PAP_assoc PF03828.14 EXF84109.1 - 1.1e-16 60.5 0.0 7.1e-11 41.8 0.0 2.7 2 0 0 2 2 2 2 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EXF84109.1 - 0.0057 16.9 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain TFIIF_alpha PF05793.7 EXF84110.1 - 1.5e-07 30.2 58.2 1.5e-07 30.2 40.3 1.8 2 1 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Bud13 PF09736.4 EXF84111.1 - 7e-45 152.8 3.2 7e-45 152.8 2.2 2.2 2 1 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex TRAPPC-Trs85 PF12739.2 EXF84112.1 - 1.8e-115 385.9 0.2 1.6e-114 382.7 0.0 1.9 2 0 0 2 2 2 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit Snf7 PF03357.16 EXF84113.1 - 1.6e-16 60.1 17.0 2.4e-16 59.5 11.8 1.3 1 0 0 1 1 1 1 Snf7 AAA_13 PF13166.1 EXF84113.1 - 9.1 4.6 11.6 8.6 4.6 7.0 1.5 1 1 1 2 2 2 0 AAA domain zf-C3HC4 PF00097.20 EXF84114.1 - 1.5e-07 30.9 19.9 3.4e-07 29.8 9.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EXF84114.1 - 1.1e-06 28.4 13.6 1.1e-06 28.4 9.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EXF84114.1 - 1.7e-06 27.7 18.1 6e-06 25.9 8.8 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EXF84114.1 - 1.8e-06 27.4 10.8 1.8e-06 27.4 7.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EXF84114.1 - 3.6e-06 26.5 12.9 3.6e-06 26.5 8.9 2.2 2 0 0 2 2 2 1 zinc-RING finger domain SAP PF02037.22 EXF84114.1 - 4.9e-05 22.7 0.1 0.00012 21.5 0.1 1.7 1 0 0 1 1 1 1 SAP domain zf-C3HC4_4 PF15227.1 EXF84114.1 - 0.0001 22.0 12.6 0.0001 22.0 8.7 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EXF84114.1 - 0.00016 21.3 4.7 0.00016 21.3 3.3 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein U-box PF04564.10 EXF84114.1 - 0.0017 18.2 0.0 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 U-box domain zf-RING_UBOX PF13445.1 EXF84114.1 - 0.0034 17.0 11.0 0.0034 17.0 7.6 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EXF84114.1 - 0.035 14.2 9.4 0.044 13.8 4.1 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger Mob_synth_C PF06463.8 EXF84114.1 - 0.041 13.5 4.3 0.1 12.3 3.0 1.6 1 0 0 1 1 1 0 Molybdenum Cofactor Synthesis C DUF4557 PF15101.1 EXF84114.1 - 7.1 6.4 7.0 1.1 9.0 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) CDC27 PF09507.5 EXF84115.1 - 3e-87 293.6 27.7 9.1e-87 292.0 19.2 1.6 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 DUF1237 PF06824.6 EXF84116.1 - 1.1e-177 590.8 0.0 1.3e-177 590.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1237) Pkinase PF00069.20 EXF84117.1 - 2.8e-43 147.9 0.0 7.6e-43 146.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF84117.1 - 1.1e-22 80.3 0.0 2.9e-22 78.9 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Hex_IIIa PF02455.11 EXF84117.1 - 1.8 7.1 4.6 3.1 6.3 3.2 1.3 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) Aa_trans PF01490.13 EXF84118.1 - 1e-05 24.2 9.6 0.00026 19.5 2.2 2.1 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein DUF2975 PF11188.3 EXF84118.1 - 0.38 10.4 8.9 0.45 10.2 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2975) ABC2_membrane_4 PF12730.2 EXF84118.1 - 0.89 8.6 13.5 2.5 7.1 9.5 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein Glyco_hydro_71 PF03659.9 EXF84119.1 - 2.4e-132 441.0 7.8 6.2e-131 436.4 5.4 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 71 PI-PLC-X PF00388.14 EXF84119.1 - 0.068 12.5 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain TMEM154 PF15102.1 EXF84120.1 - 0.0055 16.4 0.1 0.015 15.0 0.0 1.8 1 1 0 1 1 1 1 TMEM154 protein family Sarcoglycan_2 PF05510.8 EXF84120.1 - 0.068 11.4 0.0 0.087 11.1 0.0 1.1 1 0 0 1 1 1 0 Sarcoglycan alpha/epsilon CFEM PF05730.6 EXF84121.1 - 9.8e-05 22.1 3.3 0.00021 21.0 2.3 1.6 1 0 0 1 1 1 1 CFEM domain SKG6 PF08693.5 EXF84121.1 - 0.012 14.9 1.0 0.017 14.4 0.0 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain ADH_zinc_N PF00107.21 EXF84122.1 - 1.3e-24 86.2 0.3 2.1e-24 85.5 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF84122.1 - 8.3e-21 73.8 0.1 1.9e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EXF84122.1 - 0.034 14.1 0.3 0.062 13.2 0.2 1.4 1 0 0 1 1 1 0 NADH(P)-binding DapB_N PF01113.15 EXF84122.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Git3 PF11710.3 EXF84123.1 - 3.1e-22 79.1 6.2 4.4e-22 78.6 4.3 1.2 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 7tm_1 PF00001.16 EXF84123.1 - 9.6e-15 54.4 0.0 1.5e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Dicty_CAR PF05462.6 EXF84123.1 - 8.6e-09 34.7 9.2 2.6e-07 29.8 4.8 2.1 2 0 0 2 2 2 2 Slime mold cyclic AMP receptor Git3_C PF11970.3 EXF84123.1 - 0.00016 21.3 0.3 0.0024 17.6 0.0 2.5 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Cu_amine_oxid PF01179.15 EXF84124.1 - 5.7e-92 308.5 2.3 7.5e-92 308.1 1.6 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain DUF1965 PF09248.5 EXF84124.1 - 1.5e-07 31.2 0.0 5e-07 29.5 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) MFS_1 PF07690.11 EXF84125.1 - 1.1e-19 70.4 29.6 1.2e-17 63.6 15.2 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EXF84125.1 - 0.012 15.3 1.2 0.026 14.2 0.0 2.1 2 0 0 2 2 2 0 MFS_1 like family EHN PF06441.7 EXF84126.1 - 4e-30 104.0 0.3 6.7e-30 103.2 0.2 1.4 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EXF84126.1 - 5.5e-07 29.6 0.8 5e-06 26.5 0.1 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family adh_short_C2 PF13561.1 EXF84127.1 - 1.9e-31 109.7 0.0 2.3e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EXF84127.1 - 1.8e-25 89.7 0.1 2.5e-25 89.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF84127.1 - 2.2e-15 56.7 0.0 3.4e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EXF84127.1 - 0.00016 20.4 0.2 0.00031 19.5 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family DLH PF01738.13 EXF84128.1 - 6.2e-29 100.8 0.0 7.3e-29 100.6 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EXF84128.1 - 8e-07 28.9 0.0 1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF84128.1 - 0.0037 17.1 0.0 0.12 12.2 0.0 2.0 1 1 0 2 2 2 1 Alpha/beta hydrolase family Zn_clus PF00172.13 EXF84129.1 - 2.8e-06 27.1 12.0 4.9e-06 26.3 8.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF84129.1 - 0.0001 21.2 3.2 0.00016 20.6 0.8 2.3 2 1 0 2 2 2 1 Fungal specific transcription factor domain ROS_MUCR PF05443.6 EXF84129.1 - 0.019 14.7 0.0 2.3 8.0 0.0 2.4 2 0 0 2 2 2 0 ROS/MUCR transcriptional regulator protein YlbD_coat PF14071.1 EXF84129.1 - 0.092 12.8 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 Putative coat protein SnoaL PF07366.7 EXF84130.1 - 0.0061 16.1 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EXF84130.1 - 0.11 12.8 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain Pyr_redox_3 PF13738.1 EXF84131.1 - 1.1e-24 87.6 0.0 3.7e-22 79.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF84131.1 - 4.2e-13 48.9 0.0 1.8e-12 46.8 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EXF84131.1 - 5.6e-13 47.9 0.0 1.3e-11 43.3 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.9 EXF84131.1 - 4.8e-05 23.3 0.0 8.2e-05 22.5 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF84131.1 - 0.00053 19.9 0.2 0.0081 16.1 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EXF84131.1 - 0.13 12.6 0.1 0.53 10.7 0.1 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NmrA PF05368.8 EXF84132.1 - 2.1e-14 53.3 0.0 2.7e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF84132.1 - 2.6e-12 47.1 0.0 4.3e-12 46.4 0.0 1.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF84132.1 - 0.024 14.0 0.0 0.081 12.3 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Metallophos PF00149.23 EXF84133.1 - 2e-07 30.5 0.0 1e-06 28.3 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EXF84133.1 - 0.00017 21.4 0.0 0.00032 20.5 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Methyltransf_23 PF13489.1 EXF84134.1 - 1.3e-18 67.2 0.0 2.2e-18 66.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF84134.1 - 2.4e-12 47.4 0.0 1.2e-11 45.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF84134.1 - 3.1e-10 39.8 0.0 1.4e-09 37.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF84134.1 - 6.4e-08 32.9 0.0 1.4e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF84134.1 - 2.2e-07 31.2 0.0 1.8e-06 28.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EXF84134.1 - 0.00032 20.2 0.0 0.00048 19.6 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EXF84134.1 - 0.00045 20.5 0.0 0.0013 19.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF84134.1 - 0.0011 18.4 0.1 0.014 14.7 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EXF84134.1 - 0.0042 17.1 0.1 0.05 13.6 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EXF84134.1 - 0.013 14.7 0.0 0.02 14.0 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_4 PF02390.12 EXF84134.1 - 0.023 13.7 0.0 0.039 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FtsJ PF01728.14 EXF84134.1 - 0.027 14.4 0.0 0.046 13.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase PrmA PF06325.8 EXF84134.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) HET PF06985.6 EXF84135.1 - 7.2e-15 55.3 0.0 1.7e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ank_2 PF12796.2 EXF84136.1 - 7.7e-40 135.1 11.5 4.5e-12 46.1 0.0 4.1 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EXF84136.1 - 4.3e-20 71.6 2.6 0.00044 20.6 0.1 4.7 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EXF84136.1 - 2.4e-18 64.9 12.5 0.0003 20.4 0.2 6.5 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.1 EXF84136.1 - 6.8e-15 54.7 2.5 2.3e-05 24.4 0.0 4.0 2 1 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF84136.1 - 1.6e-08 33.9 7.0 1 9.8 0.1 6.5 7 0 0 7 7 7 3 Ankyrin repeat Cu-oxidase_2 PF07731.9 EXF84138.1 - 9.5e-24 83.4 0.8 2.4e-22 78.9 0.5 2.5 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_3 PF07732.10 EXF84138.1 - 8.2e-20 70.6 0.0 2.5e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase PF00394.17 EXF84138.1 - 0.00011 22.1 0.0 0.00028 20.8 0.0 1.8 1 1 0 1 1 1 1 Multicopper oxidase Sulfate_transp PF00916.15 EXF84139.1 - 4.4e-69 232.5 6.6 7.5e-69 231.8 4.6 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EXF84139.1 - 2.7e-30 103.8 2.8 2.7e-30 103.8 1.9 2.7 3 0 0 3 3 3 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EXF84139.1 - 8.6e-09 34.8 0.0 1.6e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 STAS domain PMI_typeI PF01238.16 EXF84140.1 - 2.5e-72 243.9 0.0 1.3e-70 238.3 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 EXF84140.1 - 3.5e-06 26.4 0.2 0.0057 16.1 0.1 2.6 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EXF84140.1 - 2.5e-05 23.9 0.0 0.00046 19.8 0.0 2.2 2 0 0 2 2 2 1 AraC-like ligand binding domain Cupin_3 PF05899.7 EXF84140.1 - 0.0062 15.8 0.4 0.11 11.9 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF861) GLTP PF08718.6 EXF84144.1 - 2.4e-47 160.7 0.0 3.2e-47 160.3 0.0 1.2 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) PLDc PF00614.17 EXF84146.1 - 2.2e-14 52.6 2.7 1.3e-06 27.9 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EXF84146.1 - 6.7e-12 45.2 0.0 5.7e-05 22.8 0.0 3.5 3 0 0 3 3 3 3 PLD-like domain TPR_11 PF13414.1 EXF84147.1 - 1.5e-12 46.9 0.6 1.5e-12 46.9 0.4 2.2 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EXF84147.1 - 9.7e-06 25.1 3.9 0.0034 17.1 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EXF84147.1 - 2.4e-05 24.1 0.7 6.8e-05 22.7 0.5 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EXF84147.1 - 0.00066 19.1 3.8 0.0074 15.8 0.0 3.4 4 1 1 5 5 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EXF84147.1 - 0.014 15.5 0.4 0.028 14.5 0.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EXF84147.1 - 0.071 13.7 4.3 0.38 11.5 0.0 3.4 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.1 EXF84147.1 - 0.13 12.5 0.2 0.13 12.5 0.1 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EXF84147.1 - 0.81 10.4 7.5 0.36 11.5 0.2 3.0 2 2 0 2 2 2 0 Tetratricopeptide repeat DUF3715 PF12509.3 EXF84147.1 - 4.2 7.2 8.3 0.31 10.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3715) Med2 PF11214.3 EXF84147.1 - 7.5 6.6 6.9 0.24 11.4 0.1 2.1 3 0 0 3 3 3 0 Mediator complex subunit 2 HAD_2 PF13419.1 EXF84148.1 - 1.1e-13 51.7 0.0 2.4e-12 47.3 0.0 2.1 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EXF84148.1 - 5.7e-06 26.8 0.0 0.00061 20.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EXF84148.1 - 1.1e-05 25.0 0.0 2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Fungal_trans_2 PF11951.3 EXF84149.1 - 4.6e-08 32.0 0.1 4.6e-08 32.0 0.1 1.9 2 1 0 2 2 2 1 Fungal specific transcription factor domain Pantoate_ligase PF02569.10 EXF84150.1 - 9.9e-82 273.8 0.0 1.6e-81 273.1 0.0 1.3 1 1 0 1 1 1 1 Pantoate-beta-alanine ligase Acyltransferase PF01553.16 EXF84151.1 - 2.4e-17 62.6 0.0 4.9e-17 61.6 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase UPF0086 PF01868.11 EXF84152.1 - 6.1e-23 80.2 0.0 8.7e-23 79.7 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Mitofilin PF09731.4 EXF84153.1 - 0.099 11.2 20.3 0.05 12.2 12.5 1.6 2 0 0 2 2 2 0 Mitochondrial inner membrane protein adh_short PF00106.20 EXF84154.1 - 1e-32 113.3 0.2 1.4e-32 112.9 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF84154.1 - 9.7e-30 104.0 0.0 1.2e-29 103.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF84154.1 - 1.7e-13 50.6 0.0 2.9e-13 49.8 0.0 1.3 1 1 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.14 EXF84154.1 - 0.015 14.3 0.0 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain tRNA-synt_1b PF00579.20 EXF84155.1 - 6.4e-20 71.4 0.0 1.3e-19 70.4 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) HET PF06985.6 EXF84156.1 - 4.9e-19 68.8 0.0 8e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Pkinase PF00069.20 EXF84157.1 - 1.8e-49 168.2 0.0 4.1e-25 88.4 0.1 2.9 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EXF84157.1 - 8.8e-34 116.7 0.0 1.2e-18 67.1 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EXF84157.1 - 0.0094 14.7 0.0 0.89 8.2 0.0 2.4 2 0 0 2 2 2 2 Poxvirus serine/threonine protein kinase APH PF01636.18 EXF84157.1 - 0.16 11.6 1.0 8.5 6.0 0.0 2.7 2 1 0 2 2 2 0 Phosphotransferase enzyme family Fungal_trans PF04082.13 EXF84159.1 - 1.9e-06 26.9 0.1 0.0089 14.9 0.0 2.2 1 1 1 2 2 2 2 Fungal specific transcription factor domain Abhydrolase_6 PF12697.2 EXF84160.1 - 2.1e-26 93.1 0.0 2.9e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF84160.1 - 2.8e-08 33.6 0.0 6.6e-08 32.4 0.0 1.6 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF84160.1 - 4.3e-07 29.7 0.0 6.9e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ndr PF03096.9 EXF84160.1 - 0.0087 14.5 0.0 0.027 12.9 0.0 1.6 2 0 0 2 2 2 1 Ndr family PGAP1 PF07819.8 EXF84160.1 - 0.015 14.8 0.0 0.034 13.7 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein Ser_hydrolase PF06821.8 EXF84160.1 - 0.036 13.6 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase Hydrolase_4 PF12146.3 EXF84160.1 - 0.045 13.6 0.0 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 Putative lysophospholipase DUF1057 PF06342.7 EXF84160.1 - 0.049 12.4 0.1 0.17 10.6 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF1057) Thioesterase PF00975.15 EXF84160.1 - 0.088 13.0 0.1 0.2 11.8 0.0 1.8 1 1 0 1 1 1 0 Thioesterase domain HpcH_HpaI PF03328.9 EXF84161.1 - 5e-25 87.6 0.0 2.5e-21 75.5 0.0 2.1 1 1 1 2 2 2 2 HpcH/HpaI aldolase/citrate lyase family MFS_1 PF07690.11 EXF84162.1 - 4.7e-24 84.7 17.2 6.2e-24 84.3 11.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily COesterase PF00135.23 EXF84163.1 - 4.7e-78 263.2 0.0 7.2e-78 262.6 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family DUF3176 PF11374.3 EXF84163.1 - 1.2e-30 105.6 0.9 2.3e-30 104.7 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3176) Abhydrolase_3 PF07859.8 EXF84163.1 - 6.5e-06 25.8 0.1 0.007 15.9 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold Lactate_perm PF02652.9 EXF84163.1 - 0.1 11.0 0.2 0.15 10.5 0.1 1.1 1 0 0 1 1 1 0 L-lactate permease Aminotran_1_2 PF00155.16 EXF84164.1 - 4.3e-14 52.2 0.0 1.6e-13 50.3 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class I and II Transp_cyt_pur PF02133.10 EXF84165.1 - 1.5e-77 261.0 38.0 1.7e-77 260.8 26.3 1.0 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin COX14 PF14880.1 EXF84165.1 - 1.3 8.6 3.5 1.7 8.3 0.0 2.6 2 0 0 2 2 2 0 Cytochrome oxidase c assembly Fungal_trans_2 PF11951.3 EXF84166.1 - 7.8e-25 87.2 0.1 1.2e-24 86.6 0.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF84166.1 - 6.4e-08 32.3 8.3 1.1e-07 31.6 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EphA2_TM PF14575.1 EXF84167.1 - 1.4e-06 28.5 0.1 2.5e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain DUF1183 PF06682.7 EXF84167.1 - 1.8e-06 27.7 0.8 2e-06 27.6 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) Adeno_E3_CR2 PF02439.10 EXF84167.1 - 0.00018 20.9 4.7 0.00028 20.3 3.2 1.2 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 Rifin_STEVOR PF02009.11 EXF84167.1 - 0.0014 18.3 0.6 0.0017 18.0 0.4 1.1 1 0 0 1 1 1 1 Rifin/stevor family GRP PF07172.6 EXF84167.1 - 0.0023 18.3 6.2 0.0037 17.7 4.3 1.3 1 0 0 1 1 1 1 Glycine rich protein family IncA PF04156.9 EXF84167.1 - 0.0074 15.8 0.0 0.0095 15.5 0.0 1.1 1 0 0 1 1 1 1 IncA protein Herpes_gE PF02480.11 EXF84167.1 - 0.0094 14.2 0.1 0.011 13.9 0.1 1.1 1 0 0 1 1 1 1 Alphaherpesvirus glycoprotein E Shisa PF13908.1 EXF84167.1 - 0.012 15.8 0.1 0.017 15.3 0.0 1.3 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DAG1 PF05454.6 EXF84167.1 - 0.021 14.0 0.3 0.028 13.5 0.2 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) CD34_antigen PF06365.7 EXF84167.1 - 0.12 12.0 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 CD34/Podocalyxin family SKG6 PF08693.5 EXF84167.1 - 0.23 10.7 7.8 0.41 10.0 5.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RCR PF12273.3 EXF84167.1 - 0.34 11.4 10.1 1 9.9 7.0 1.8 1 1 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Syndecan PF01034.15 EXF84167.1 - 1.2 8.8 3.5 2.8 7.6 2.4 1.6 1 0 0 1 1 1 0 Syndecan domain Glyco_hydro_76 PF03663.9 EXF84168.1 - 3.7e-136 454.3 7.5 4.9e-136 453.9 5.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF4623 PF15416.1 EXF84168.1 - 0.09 11.1 0.0 0.13 10.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4623) HET PF06985.6 EXF84170.1 - 3.5e-25 88.7 0.0 7.8e-25 87.6 0.0 1.6 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) OPT PF03169.10 EXF84171.1 - 1.3e-90 304.6 47.8 1.5e-90 304.4 33.1 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein GFA PF04828.9 EXF84172.1 - 0.00019 21.3 14.5 0.00039 20.3 0.6 2.9 3 1 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme Cupin_2 PF07883.6 EXF84173.1 - 9.3e-15 53.8 0.1 1.7e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EXF84173.1 - 4.1e-05 23.0 0.0 5.6e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Cupin AraC_binding PF02311.14 EXF84173.1 - 6e-05 22.7 0.0 8.8e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain ARD PF03079.9 EXF84173.1 - 0.00015 21.7 0.3 0.00036 20.5 0.0 1.6 2 0 0 2 2 2 1 ARD/ARD' family Cupin_6 PF12852.2 EXF84173.1 - 0.0014 18.2 0.0 0.0017 17.9 0.0 1.2 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.7 EXF84173.1 - 0.0021 17.4 0.0 0.0041 16.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) JmjC PF02373.17 EXF84173.1 - 0.0051 17.0 0.0 0.009 16.2 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase GPI PF06560.6 EXF84173.1 - 0.025 13.6 0.0 0.038 13.0 0.0 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) FA_desaturase PF00487.19 EXF84174.1 - 3.6e-11 43.0 31.6 1.5e-10 40.9 21.8 1.8 1 1 0 1 1 1 1 Fatty acid desaturase Haemolytic PF01809.13 EXF84176.1 - 0.27 10.8 2.0 0.27 10.8 1.4 1.1 1 0 0 1 1 1 0 Haemolytic domain Abhydrolase_5 PF12695.2 EXF84177.1 - 6.9e-10 38.8 0.0 1.5e-09 37.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EXF84177.1 - 5.8e-05 22.4 0.0 0.00015 21.1 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.6 EXF84177.1 - 0.00013 21.7 0.0 0.00021 21.0 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 EXF84177.1 - 0.002 17.3 0.0 0.0036 16.5 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.3 EXF84177.1 - 0.0024 17.7 0.0 0.0056 16.5 0.0 1.7 1 0 0 1 1 1 1 Putative lysophospholipase COesterase PF00135.23 EXF84178.1 - 2.5e-90 303.7 0.0 3.3e-90 303.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF84178.1 - 0.0019 17.8 0.3 0.0079 15.7 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold GFO_IDH_MocA PF01408.17 EXF84179.1 - 2.3e-15 57.1 0.3 4.4e-15 56.2 0.2 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NmrA PF05368.8 EXF84180.1 - 7.4e-20 71.2 1.7 5.1e-19 68.4 1.2 2.0 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF84180.1 - 4.1e-11 43.2 0.5 1.1e-10 41.8 0.3 1.7 1 1 0 1 1 1 1 NADH(P)-binding DapB_N PF01113.15 EXF84180.1 - 0.013 15.4 0.2 0.051 13.4 0.1 1.9 1 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus FAD_binding_4 PF01565.18 EXF84181.1 - 1.3e-25 89.5 0.3 2.1e-25 88.8 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF84181.1 - 0.00028 20.7 1.7 0.0006 19.6 0.1 2.2 2 0 0 2 2 2 1 Berberine and berberine like GMC_oxred_N PF00732.14 EXF84182.1 - 5.7e-57 193.1 0.0 7.4e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF84182.1 - 5.8e-35 120.6 0.0 9.5e-35 119.9 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EXF84182.1 - 6.7e-07 28.5 0.3 0.019 13.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EXF84182.1 - 1.4e-05 24.2 0.0 0.00062 18.7 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF84182.1 - 9.3e-05 22.3 0.1 0.00037 20.4 0.1 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF84182.1 - 0.001 18.9 0.1 0.26 11.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF84182.1 - 0.0077 16.3 0.6 4.2 7.3 0.2 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF84182.1 - 0.017 14.0 0.2 0.045 12.6 0.0 1.7 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 EXF84182.1 - 0.027 14.2 0.1 0.071 12.8 0.0 1.7 2 0 0 2 2 2 0 FAD-NAD(P)-binding Thi4 PF01946.12 EXF84182.1 - 0.039 13.0 0.1 0.093 11.8 0.0 1.5 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 EXF84182.1 - 0.12 12.7 0.3 0.39 11.1 0.2 1.9 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 EXF84184.1 - 4.4e-16 58.5 20.8 5.5e-08 31.9 0.1 2.8 1 1 2 3 3 3 3 Major Facilitator Superfamily DUF1049 PF06305.6 EXF84184.1 - 0.76 9.3 0.0 0.76 9.3 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) DUF3302 PF11742.3 EXF84184.1 - 6.2 6.7 7.9 27 4.7 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3302) DIOX_N PF14226.1 EXF84185.1 - 5.3e-19 68.8 0.0 1e-18 67.9 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EXF84185.1 - 4.9e-12 46.0 0.0 8.6e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EXF84186.1 - 6.6e-32 110.4 0.0 1.4e-31 109.4 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EXF84186.1 - 1.8e-15 57.0 0.0 4.2e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_M6 PF05547.6 EXF84187.1 - 4.6e-07 28.2 0.2 0.0045 15.0 0.6 2.1 2 0 0 2 2 2 2 Immune inhibitor A peptidase M6 7TMR-DISMED2 PF07696.6 EXF84187.1 - 0.052 12.9 0.0 0.14 11.5 0.0 1.7 1 0 0 1 1 1 0 7TMR-DISM extracellular 2 Cellulase PF00150.13 EXF84188.1 - 7.4e-47 159.8 0.9 1.1e-46 159.2 0.6 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) CBM_1 PF00734.13 EXF84188.1 - 4.8e-11 42.1 8.6 4.8e-11 42.1 5.9 2.6 3 0 0 3 3 3 1 Fungal cellulose binding domain Peptidase_S41 PF03572.13 EXF84191.1 - 1.7e-07 30.8 0.0 3.6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S41 Paramyxo_PCT PF14320.1 EXF84191.1 - 0.054 12.3 0.1 0.084 11.7 0.1 1.2 1 0 0 1 1 1 0 Phosphoprotein P region PCT disordered GATase PF00117.23 EXF84192.1 - 1.2e-09 37.9 0.0 2.7e-09 36.7 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EXF84192.1 - 0.006 16.0 0.0 0.088 12.2 0.0 2.5 1 1 0 1 1 1 1 Peptidase C26 Phage_base_V PF04717.7 EXF84192.1 - 0.13 12.2 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Phage-related baseplate assembly protein Fungal_trans_2 PF11951.3 EXF84193.1 - 0.0084 14.7 1.6 0.01 14.4 0.3 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain DUF3722 PF12519.3 EXF84194.1 - 2.1e-81 272.9 0.0 3.5e-81 272.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) Porin_3 PF01459.17 EXF84194.1 - 9.4e-06 25.1 0.2 0.016 14.4 0.0 2.7 3 0 0 3 3 3 2 Eukaryotic porin Zip PF02535.17 EXF84195.1 - 1.9e-48 165.1 11.2 2.7e-48 164.6 7.8 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter Ribosomal_S19e PF01090.14 EXF84196.1 - 4.2e-58 194.7 0.2 4.8e-58 194.5 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e MFS_1 PF07690.11 EXF84198.1 - 3.3e-49 167.4 45.2 6.6e-48 163.2 20.3 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF84198.1 - 9.4e-13 47.5 7.7 9.4e-13 47.5 5.3 2.5 1 1 1 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EXF84198.1 - 7.6e-08 31.0 0.4 1.4e-07 30.0 0.3 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OATP PF03137.15 EXF84198.1 - 9.9 4.0 14.3 5.2 5.0 0.6 3.6 4 0 0 4 4 4 0 Organic Anion Transporter Polypeptide (OATP) family 4HBT PF03061.17 EXF84199.1 - 1.4e-14 53.9 0.0 1.9e-14 53.5 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily KH_1 PF00013.24 EXF84199.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 KH domain Zn_clus PF00172.13 EXF84200.1 - 7.6e-08 32.1 7.5 7.6e-08 32.1 5.2 1.6 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF84200.1 - 0.00036 19.2 1.3 0.0014 17.3 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Polysacc_deac_1 PF01522.16 EXF84202.1 - 1.4e-31 108.6 0.0 2e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EXF84202.1 - 0.003 16.5 0.0 0.0039 16.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Glyco_hydro_18 PF00704.23 EXF84203.1 - 7.7e-70 236.0 0.3 9.4e-70 235.7 0.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF3142 PF11340.3 EXF84203.1 - 3.2e-05 23.6 0.0 5.2e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3142) Ricin_B_lectin PF00652.17 EXF84204.1 - 2.1e-16 60.0 0.5 8.7e-06 25.7 0.0 4.2 2 2 2 4 4 4 4 Ricin-type beta-trefoil lectin domain CDtoxinA PF03498.9 EXF84204.1 - 0.076 12.3 6.2 1.9 7.8 0.2 3.6 2 2 1 4 4 4 0 Cytolethal distending toxin A/C family CorA PF01544.13 EXF84205.1 - 2.7e-30 105.4 7.1 2.9e-26 92.1 3.7 2.6 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein adh_short PF00106.20 EXF84207.1 - 2.2e-28 99.2 4.1 4.5e-28 98.2 2.8 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF84207.1 - 2.1e-13 50.6 0.0 2.9e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF84207.1 - 1e-10 41.5 6.5 8.8e-10 38.5 4.5 2.0 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EXF84207.1 - 1.7e-06 28.1 0.5 3.7e-06 27.0 0.4 1.6 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF84207.1 - 4.6e-06 26.2 1.3 6.6e-06 25.7 0.2 1.8 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EXF84207.1 - 6.8e-05 21.7 0.3 0.0001 21.1 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EXF84207.1 - 0.0029 16.5 0.1 0.0045 15.9 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain TrkA_N PF02254.13 EXF84207.1 - 0.011 15.7 0.1 0.022 14.7 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain ApbA PF02558.11 EXF84207.1 - 0.015 14.7 0.3 0.068 12.6 0.2 2.0 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EXF84207.1 - 0.026 14.1 0.1 0.051 13.2 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.8 EXF84207.1 - 0.046 12.9 0.4 0.083 12.1 0.3 1.4 1 0 0 1 1 1 0 NmrA-like family Polysacc_synt_2 PF02719.10 EXF84207.1 - 0.12 11.2 0.0 0.21 10.4 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein UPF0146 PF03686.8 EXF84207.1 - 0.13 12.1 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) BOP1NT PF08145.7 EXF84209.1 - 1.7e-106 355.7 8.0 2.6e-106 355.1 5.6 1.3 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.27 EXF84209.1 - 1.9e-29 100.4 1.9 8.4e-13 47.6 0.2 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat Zn_clus PF00172.13 EXF84210.1 - 3.9e-07 29.8 10.1 7.8e-07 28.8 7.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-CSL PF05207.8 EXF84210.1 - 0.02 14.3 0.1 0.048 13.1 0.0 1.6 1 0 0 1 1 1 0 CSL zinc finger Utp21 PF04192.7 EXF84210.1 - 0.029 13.4 0.2 0.092 11.8 0.0 1.8 2 0 0 2 2 2 0 Utp21 specific WD40 associated putative domain DUF3661 PF12400.3 EXF84211.1 - 1.7e-42 144.5 3.7 3e-42 143.7 2.5 1.4 1 0 0 1 1 1 1 Vaculolar membrane protein Methyltransf_23 PF13489.1 EXF84212.1 - 1.1e-18 67.5 0.0 1.6e-18 66.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF84212.1 - 4.3e-05 24.0 0.0 0.0004 20.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF84212.1 - 0.0002 20.9 0.0 0.001 18.6 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF84212.1 - 0.0011 19.3 0.0 0.0065 16.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF84212.1 - 0.0031 17.8 0.0 0.0099 16.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF84212.1 - 0.0056 17.1 0.0 0.074 13.5 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EXF84212.1 - 0.14 11.7 0.0 0.37 10.2 0.0 1.7 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EXF84213.1 - 5.1e-41 140.0 0.0 1.2e-20 73.8 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EXF84213.1 - 2.6e-20 73.0 0.0 1.5e-08 35.1 0.0 4.2 2 2 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.1 EXF84213.1 - 5.2e-17 61.8 0.0 1.1e-07 31.5 0.0 3.7 2 2 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EXF84213.1 - 2.2e-16 60.1 0.0 5.9e-07 29.8 0.0 3.2 2 2 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EXF84213.1 - 8.3e-16 58.2 0.0 9.3e-07 29.2 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EXF84213.1 - 9.6e-08 32.3 0.0 0.01 16.2 0.0 2.9 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_4 PF02390.12 EXF84213.1 - 1.3e-07 30.8 0.2 0.11 11.5 0.0 3.5 3 0 0 3 3 3 2 Putative methyltransferase MTS PF05175.9 EXF84213.1 - 7.5e-07 28.6 0.2 0.15 11.4 0.0 4.1 5 0 0 5 5 5 2 Methyltransferase small domain FtsJ PF01728.14 EXF84213.1 - 3.8e-06 27.0 0.0 0.062 13.2 0.0 2.6 2 0 0 2 2 2 2 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EXF84213.1 - 3.2e-05 23.9 0.0 0.077 13.0 0.0 2.8 2 1 0 2 2 2 2 Methyltransferase domain PrmA PF06325.8 EXF84213.1 - 0.00021 20.5 0.0 0.083 12.0 0.0 2.4 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_16 PF10294.4 EXF84213.1 - 0.00029 20.3 0.0 0.4 10.1 0.0 2.8 3 0 0 3 3 3 2 Putative methyltransferase Ubie_methyltran PF01209.13 EXF84213.1 - 0.00089 18.4 0.0 1.2 8.1 0.0 3.5 2 2 0 2 2 2 2 ubiE/COQ5 methyltransferase family Methyltransf_17 PF12692.2 EXF84213.1 - 0.0093 15.6 0.0 8.9 5.9 0.0 3.6 4 0 0 4 4 4 1 S-adenosyl-L-methionine methyltransferase Methyltransf_2 PF00891.13 EXF84213.1 - 0.1 11.7 0.4 7 5.7 0.0 2.7 3 0 0 3 3 3 0 O-methyltransferase PCMT PF01135.14 EXF84213.1 - 0.23 10.9 0.1 22 4.5 0.0 3.1 2 2 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EXF84214.1 - 6.1e-21 74.8 0.0 8.8e-21 74.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF84214.1 - 1.2e-09 38.7 0.0 1.3e-08 35.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF84214.1 - 8.8e-08 31.8 0.0 6.5e-07 29.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF84214.1 - 7.2e-07 29.6 0.0 3.1e-06 27.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF84214.1 - 1.1e-06 28.9 0.0 2.3e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF84214.1 - 0.00066 18.7 0.0 0.0011 18.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.1 EXF84214.1 - 0.00072 19.8 0.0 0.0041 17.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF84214.1 - 0.0022 17.9 0.0 0.0044 17.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EXF84214.1 - 0.015 14.4 0.0 0.023 13.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EXF84214.1 - 0.047 13.0 0.0 0.082 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain CMAS PF02353.15 EXF84214.1 - 0.05 12.6 0.0 0.14 11.2 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase PCMT PF01135.14 EXF84214.1 - 0.069 12.6 0.0 0.29 10.6 0.0 2.0 2 1 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EXF84215.1 - 2.4e-21 76.1 0.0 3.8e-21 75.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF84215.1 - 2.5e-10 40.8 0.0 3.7e-09 37.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF84215.1 - 5.7e-08 32.4 0.0 6.5e-07 29.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF84215.1 - 2.3e-05 24.8 0.0 0.00014 22.2 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF84215.1 - 4.5e-05 23.8 0.0 0.00013 22.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF84215.1 - 0.0016 18.4 0.0 0.0064 16.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF84215.1 - 0.0045 17.3 0.0 0.013 15.8 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EXF84215.1 - 0.022 14.1 0.0 0.036 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_4 PF02390.12 EXF84215.1 - 0.028 13.4 0.0 0.051 12.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.8 EXF84215.1 - 0.031 13.3 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GidB PF02527.10 EXF84215.1 - 0.22 10.6 0.0 0.34 10.0 0.0 1.2 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_23 PF13489.1 EXF84216.1 - 2.4e-20 72.8 0.0 3.5e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF84216.1 - 6e-07 30.0 0.0 5.3e-06 26.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF84216.1 - 3.1e-06 27.5 0.0 5.5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF84216.1 - 8.7e-06 25.3 0.0 3e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF84216.1 - 0.00013 22.3 0.0 0.00035 20.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF84216.1 - 0.0013 17.8 0.0 0.24 10.4 0.0 2.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EXF84216.1 - 0.0053 17.0 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EXF84216.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase SDA1 PF05285.7 EXF84217.1 - 0.48 9.6 6.1 0.53 9.5 4.2 1.0 1 0 0 1 1 1 0 SDA1 COesterase PF00135.23 EXF84218.1 - 3.1e-100 336.4 0.0 3.8e-100 336.1 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF84218.1 - 0.0024 17.4 0.4 0.0085 15.6 0.3 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF84218.1 - 0.025 14.3 0.0 0.053 13.2 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family F-box-like PF12937.2 EXF84219.1 - 1.1e-05 25.0 0.2 2.5e-05 23.9 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EXF84219.1 - 0.0021 17.6 0.0 0.0061 16.1 0.0 1.8 1 0 0 1 1 1 1 F-box domain Gag_p12 PF01141.13 EXF84220.1 - 0.052 13.6 2.8 0.08 13.0 2.0 1.2 1 0 0 1 1 1 0 Gag polyprotein, inner coat protein p12 WSC PF01822.14 EXF84221.1 - 1.2e-17 63.6 7.8 1.5e-17 63.2 5.4 1.1 1 0 0 1 1 1 1 WSC domain IMS PF00817.15 EXF84222.1 - 7.9e-41 139.3 0.0 1.6e-40 138.3 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EXF84222.1 - 4.6e-17 62.1 0.0 1e-16 61.0 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain DUF4414 PF14377.1 EXF84222.1 - 1.4e-12 47.4 12.7 6.8e-08 32.3 0.5 3.1 3 0 0 3 3 3 2 Domain of unknown function (DUF4414) IMS_HHH PF11798.3 EXF84222.1 - 0.0015 18.4 0.3 0.011 15.6 0.0 2.7 2 0 0 2 2 2 1 IMS family HHH motif HHH_5 PF14520.1 EXF84222.1 - 0.0031 17.6 1.7 0.0067 16.5 0.0 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain MgtE_N PF03448.12 EXF84222.1 - 0.0057 16.9 0.3 4.1 7.7 0.1 3.6 3 0 0 3 3 3 1 MgtE intracellular N domain DUF1805 PF08827.6 EXF84222.1 - 0.012 15.3 0.0 0.26 11.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1805) F420_ligase PF01996.11 EXF84222.1 - 0.032 13.3 0.0 0.066 12.2 0.0 1.5 1 0 0 1 1 1 0 F420-0:Gamma-glutamyl ligase RED_N PF07808.8 EXF84223.1 - 1.9e-07 30.5 15.7 1.9e-07 30.5 10.9 2.7 2 1 0 2 2 2 1 RED-like protein N-terminal region IU_nuc_hydro PF01156.14 EXF84224.1 - 1.6e-86 290.3 0.1 1.8e-86 290.2 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Bac_rhodopsin PF01036.13 EXF84225.1 - 1.3e-32 112.9 23.9 1.7e-32 112.5 16.6 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Arm PF00514.18 EXF84226.1 - 5.1e-10 38.7 10.3 0.074 12.9 0.0 7.0 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EXF84226.1 - 5.1e-06 26.1 10.9 3 8.1 0.0 7.4 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EXF84226.1 - 0.0016 18.8 17.6 2.9 8.5 0.0 7.9 8 0 0 8 8 8 2 HEAT-like repeat Ric8 PF10165.4 EXF84226.1 - 0.089 11.6 1.2 6.1 5.5 0.0 2.9 2 1 0 2 2 2 0 Guanine nucleotide exchange factor synembryn Cyclin PF08613.6 EXF84227.1 - 3.6e-29 102.0 0.0 7.9e-29 100.9 0.0 1.6 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EXF84227.1 - 0.0012 18.3 0.1 0.0019 17.7 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Caa3_CtaG PF09678.5 EXF84228.1 - 0.051 12.4 0.3 1.8 7.4 0.0 2.1 2 0 0 2 2 2 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) CHZ PF09649.5 EXF84229.1 - 3.9e-17 61.1 0.9 3.9e-17 61.1 0.6 2.6 2 0 0 2 2 2 1 Histone chaperone domain CHZ SNARE PF05739.14 EXF84230.1 - 4.4e-09 35.9 1.2 5.8e-09 35.5 0.8 1.2 1 0 0 1 1 1 1 SNARE domain Apc15p PF05841.6 EXF84231.1 - 1.6e-21 77.3 13.3 1.6e-21 77.3 9.2 1.9 3 0 0 3 3 3 1 Apc15p protein TFIIA PF03153.8 EXF84231.1 - 1.4e-05 25.1 25.7 1.4e-05 25.1 17.8 2.6 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit PilM PF07419.7 EXF84231.1 - 0.034 13.6 2.5 0.078 12.4 1.8 1.6 1 0 0 1 1 1 0 PilM Med3 PF11593.3 EXF84231.1 - 2.2 7.4 10.8 3.3 6.8 7.5 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal RNA_pol_Rpc4 PF05132.9 EXF84231.1 - 7.4 6.5 12.1 1.4 8.8 1.4 2.7 2 1 0 2 2 2 0 RNA polymerase III RPC4 Glu_synthase PF01645.12 EXF84232.1 - 2.1e-158 527.0 0.0 3.3e-158 526.4 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase GATase_2 PF00310.16 EXF84232.1 - 2.8e-140 467.1 0.0 3.8e-140 466.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_syn_central PF04898.9 EXF84232.1 - 2.9e-117 391.0 0.0 6.2e-117 389.9 0.0 1.5 1 0 0 1 1 1 1 Glutamate synthase central domain GXGXG PF01493.14 EXF84232.1 - 1.3e-69 233.2 2.1 2.4e-69 232.3 1.4 1.4 1 0 0 1 1 1 1 GXGXG motif Fer4_20 PF14691.1 EXF84232.1 - 1.5e-22 79.3 0.1 3.8e-22 77.9 0.1 1.7 1 0 0 1 1 1 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.9 EXF84232.1 - 2e-16 60.4 0.0 1.2e-15 57.9 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF84232.1 - 7.1e-12 45.8 0.2 4.5e-05 23.6 0.0 2.7 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF84232.1 - 9.1e-09 35.2 0.3 3.2e-08 33.4 0.0 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EXF84232.1 - 5.9e-07 29.8 0.1 0.00024 21.4 0.0 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EXF84232.1 - 1.4e-06 27.6 0.1 2.8e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase DAO PF01266.19 EXF84232.1 - 5.6e-05 22.2 0.2 5.6e-05 22.2 0.1 2.1 2 1 0 2 2 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF84232.1 - 6.1e-05 22.0 0.0 0.00071 18.5 0.0 2.4 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.9 EXF84232.1 - 6.6e-05 21.5 0.1 6.6e-05 21.5 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.16 EXF84232.1 - 0.00041 19.9 0.3 0.0031 17.0 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.1 EXF84232.1 - 0.00061 20.0 0.4 0.42 10.8 0.1 3.0 2 0 0 2 2 2 1 Putative NAD(P)-binding FAD_binding_3 PF01494.14 EXF84232.1 - 0.00062 18.9 0.0 0.0013 17.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EXF84232.1 - 0.00093 18.3 0.0 0.00093 18.3 0.0 1.7 2 0 0 2 2 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 EXF84232.1 - 0.0032 17.2 0.0 0.0069 16.1 0.0 1.6 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Thi4 PF01946.12 EXF84232.1 - 0.0038 16.3 1.1 0.0086 15.1 0.0 2.0 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 EXF84232.1 - 0.016 14.1 0.5 0.11 11.3 0.0 2.3 2 0 0 2 2 2 0 Glucose inhibited division protein A FMO-like PF00743.14 EXF84232.1 - 0.034 12.3 0.0 3.1 5.9 0.0 2.8 2 1 1 3 3 3 0 Flavin-binding monooxygenase-like 2-Hacid_dh_C PF02826.14 EXF84232.1 - 0.048 12.8 0.1 0.53 9.4 0.0 2.6 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.16 EXF84232.1 - 0.061 13.1 0.2 4.1 7.2 0.0 2.8 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_9 PF13454.1 EXF84232.1 - 0.065 13.0 0.0 0.24 11.1 0.0 2.0 1 0 0 1 1 1 0 FAD-NAD(P)-binding DJ-1_PfpI PF01965.19 EXF84232.1 - 0.069 12.6 0.2 0.64 9.4 0.0 2.3 1 1 1 2 2 2 0 DJ-1/PfpI family DUF1048 PF06304.6 EXF84232.1 - 0.071 13.4 0.8 0.2 12.0 0.2 2.0 2 0 0 2 2 1 0 Protein of unknown function (DUF1048) Shikimate_DH PF01488.15 EXF84232.1 - 0.077 13.1 0.1 21 5.1 0.0 2.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EXF84232.1 - 0.11 12.9 0.0 1.6 9.1 0.0 2.7 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent FMN_dh PF01070.13 EXF84232.1 - 0.13 11.0 0.7 0.4 9.4 0.5 1.7 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Lycopene_cycl PF05834.7 EXF84232.1 - 0.15 10.9 0.1 4.5 6.0 0.1 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein 6PF2K PF01591.13 EXF84233.1 - 4e-64 215.7 0.0 7.3e-46 156.0 0.0 2.2 2 0 0 2 2 2 2 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EXF84233.1 - 9.7e-28 97.2 0.0 9.4e-27 94.0 0.0 2.4 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EXF84233.1 - 1.8e-05 24.6 0.0 5.9e-05 22.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain CARD PF00619.16 EXF84233.1 - 0.012 15.3 0.6 0.053 13.3 0.4 2.0 1 1 0 1 1 1 0 Caspase recruitment domain Sigma70_r4_2 PF08281.7 EXF84233.1 - 0.029 13.8 0.1 1.8 8.1 0.0 2.5 2 0 0 2 2 2 0 Sigma-70, region 4 KTI12 PF08433.5 EXF84233.1 - 0.03 13.5 0.0 0.056 12.6 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_17 PF13207.1 EXF84233.1 - 0.061 14.1 0.1 0.31 11.8 0.0 2.3 2 2 0 2 2 2 0 AAA domain dCMP_cyt_deam_1 PF00383.17 EXF84234.1 - 4.9e-09 35.7 0.0 9.8e-09 34.7 0.0 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region RNase_H PF00075.19 EXF84235.1 - 3.9e-27 95.1 1.3 3.3e-26 92.2 0.2 2.3 1 1 1 2 2 2 1 RNase H Cauli_VI PF01693.11 EXF84235.1 - 1.7e-23 82.3 3.4 1.1e-13 50.9 0.2 2.4 2 0 0 2 2 2 2 Caulimovirus viroplasmin BSP_II PF05432.6 EXF84235.1 - 0.0028 16.9 2.8 0.0044 16.3 1.9 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Na_H_Exchanger PF00999.16 EXF84236.1 - 6e-43 146.8 17.9 8e-43 146.3 12.4 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF3272 PF11676.3 EXF84236.1 - 0.093 12.7 0.1 0.28 11.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3272) Ank PF00023.25 EXF84238.1 - 5.5e-13 48.0 0.2 7.1e-08 31.8 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat TIG PF01833.19 EXF84238.1 - 1.1e-11 44.6 0.3 3.2e-11 43.0 0.2 1.9 1 0 0 1 1 1 1 IPT/TIG domain Ank_2 PF12796.2 EXF84238.1 - 2.4e-11 43.8 0.0 5.4e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EXF84238.1 - 2.1e-08 34.1 0.0 6.4e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EXF84238.1 - 3.2e-06 27.4 0.2 1e-05 25.8 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF84238.1 - 1.4e-05 24.8 0.1 0.0044 17.1 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat adh_short PF00106.20 EXF84240.1 - 1e-11 45.0 1.2 2.3e-11 43.8 0.8 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF84240.1 - 3.9e-11 43.1 1.8 9.9e-07 28.7 0.1 2.6 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF84240.1 - 8.8e-07 28.7 3.1 1.7e-06 27.8 1.4 1.9 2 0 0 2 2 2 1 KR domain Saccharop_dh PF03435.13 EXF84240.1 - 1.1e-05 24.5 1.1 1.6e-05 24.0 0.8 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Pyr_redox_2 PF07992.9 EXF84240.1 - 0.003 17.4 1.3 0.0045 16.8 0.8 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 3Beta_HSD PF01073.14 EXF84240.1 - 0.0045 15.7 0.2 0.0072 15.0 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Pyr_redox PF00070.22 EXF84240.1 - 0.0055 17.0 0.1 0.018 15.4 0.1 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 EXF84240.1 - 0.046 14.1 1.1 0.046 14.1 0.8 2.1 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EXF84240.1 - 0.064 12.6 0.3 0.11 11.8 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF1786 PF08735.5 EXF84240.1 - 0.18 10.9 1.1 0.73 8.9 0.1 2.0 1 1 1 2 2 2 0 Putative pyruvate format-lyase activating enzyme (DUF1786) DAO PF01266.19 EXF84240.1 - 0.27 10.1 7.5 0.57 9.0 2.4 2.3 1 1 1 2 2 2 0 FAD dependent oxidoreductase Nic96 PF04097.9 EXF84241.1 - 6.9e-211 701.5 0.0 8.6e-211 701.2 0.0 1.1 1 0 0 1 1 1 1 Nup93/Nic96 Nucleoporin_FG PF13634.1 EXF84241.1 - 4.4e-10 39.8 47.6 4.4e-10 39.8 33.0 3.5 2 1 1 3 3 3 2 Nucleoporin FG repeat region JmjC PF02373.17 EXF84242.1 - 2.3e-10 40.6 0.1 7.8e-10 39.0 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 EXF84242.1 - 8.5e-07 29.0 11.9 8.5e-07 29.0 8.2 2.7 2 1 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Cupin_2 PF07883.6 EXF84242.1 - 0.0029 17.0 0.0 0.0063 15.9 0.0 1.5 1 0 0 1 1 1 1 Cupin domain UbiA PF01040.13 EXF84243.1 - 2e-31 109.1 21.8 2.7e-31 108.7 15.1 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Ribosom_S12_S23 PF00164.20 EXF84244.1 - 1e-40 137.9 0.5 1.1e-40 137.7 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Inhibitor_I9 PF05922.11 EXF84246.1 - 0.00016 22.1 0.0 0.00018 21.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase inhibitor I9 FANCI_S2 PF14676.1 EXF84246.1 - 0.13 12.1 0.0 0.15 11.9 0.0 1.1 1 0 0 1 1 1 0 FANCI solenoid 2 HOOK PF05622.7 EXF84247.1 - 4.2e-05 21.5 84.5 0.0024 15.7 36.6 3.9 2 1 2 4 4 4 3 HOOK protein Reo_sigmaC PF04582.7 EXF84247.1 - 1 8.5 20.5 0.43 9.6 0.6 4.2 2 2 1 3 3 3 0 Reovirus sigma C capsid protein ADK PF00406.17 EXF84248.1 - 6.4e-49 165.7 0.3 1.4e-48 164.5 0.2 1.6 1 1 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EXF84248.1 - 6.7e-14 51.2 0.1 1.9e-13 49.8 0.0 1.8 2 0 0 2 2 2 1 Adenylate kinase, active site lid MitMem_reg PF13012.1 EXF84249.1 - 1.2e-38 131.7 0.0 2.4e-38 130.7 0.0 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EXF84249.1 - 1.1e-27 96.0 0.0 2.6e-27 94.8 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SWIM PF04434.12 EXF84250.1 - 0.00028 20.2 0.9 0.21 11.0 0.1 2.5 2 0 0 2 2 2 2 SWIM zinc finger DUF3439 PF11921.3 EXF84250.1 - 3.9 7.2 6.3 13 5.5 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Coprogen_oxidas PF01218.13 EXF84251.1 - 2.3e-134 446.6 0.1 2.8e-134 446.3 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Atg8 PF02991.11 EXF84252.1 - 2.6e-51 171.8 0.2 3.1e-51 171.6 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EXF84252.1 - 2.7e-06 27.4 0.0 3.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 ABC_membrane PF00664.18 EXF84253.1 - 3.1e-75 253.1 27.3 2.6e-41 141.8 2.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EXF84253.1 - 8.2e-65 217.2 0.0 8.1e-33 113.6 0.0 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EXF84253.1 - 3e-16 59.3 0.3 4.5e-05 22.7 0.0 4.3 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EXF84253.1 - 3.2e-08 33.9 0.3 0.21 11.5 0.0 4.3 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EXF84253.1 - 2.8e-07 29.9 2.2 0.0083 15.6 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EXF84253.1 - 2.9e-07 30.6 0.6 0.033 14.1 0.1 2.8 2 1 0 2 2 2 2 AAA ATPase domain ABC_ATPase PF09818.4 EXF84253.1 - 6.7e-07 28.2 0.3 0.0012 17.5 0.0 2.7 2 1 0 2 2 2 2 Predicted ATPase of the ABC class AAA_17 PF13207.1 EXF84253.1 - 1.9e-06 28.6 0.0 0.11 13.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EXF84253.1 - 6.5e-06 26.3 3.1 0.45 10.6 0.1 5.1 4 1 0 4 4 4 1 AAA domain DUF258 PF03193.11 EXF84253.1 - 7.7e-06 25.1 0.0 0.01 15.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_30 PF13604.1 EXF84253.1 - 8.4e-06 25.4 9.3 0.016 14.7 0.0 5.5 6 0 0 6 6 6 2 AAA domain AAA_25 PF13481.1 EXF84253.1 - 1e-05 25.0 0.3 0.24 10.7 0.0 3.8 4 0 0 4 4 4 2 AAA domain Zeta_toxin PF06414.7 EXF84253.1 - 2.4e-05 23.5 0.1 0.19 10.8 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin APS_kinase PF01583.15 EXF84253.1 - 0.00019 21.1 0.2 0.055 13.1 0.0 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase SbcCD_C PF13558.1 EXF84253.1 - 0.00035 20.4 0.4 1.1 9.2 0.1 3.2 2 1 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EXF84253.1 - 0.00035 20.4 0.1 0.52 10.1 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 EXF84253.1 - 0.00039 20.6 0.4 1.4 9.1 0.1 4.3 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EXF84253.1 - 0.00095 18.6 0.9 3.1 7.1 0.1 3.2 3 0 0 3 3 3 1 AAA-like domain AAA_18 PF13238.1 EXF84253.1 - 0.0035 17.6 0.0 1.8 8.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EXF84253.1 - 0.018 14.9 0.0 1.9 8.4 0.0 2.9 3 0 0 3 3 2 0 AAA domain AAA_23 PF13476.1 EXF84253.1 - 0.026 14.8 7.0 1.6 9.0 0.2 3.3 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.9 EXF84253.1 - 0.035 13.8 0.0 9 6.0 0.0 3.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 EXF84253.1 - 0.048 12.5 0.2 6.6 5.4 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain MobB PF03205.9 EXF84253.1 - 0.052 13.2 0.5 6.8 6.3 0.0 2.8 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EXF84253.1 - 0.094 12.6 0.2 18 5.3 0.0 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF3987 PF13148.1 EXF84253.1 - 0.1 11.1 7.0 2.8 6.3 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) Herpes_DNAp_acc PF04929.7 EXF84253.1 - 0.31 9.9 2.1 0.67 8.8 1.4 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF87 PF01935.12 EXF84253.1 - 0.5 10.1 7.2 1 9.1 0.1 3.1 3 1 0 3 3 3 0 Domain of unknown function DUF87 DUF904 PF06005.7 EXF84253.1 - 0.94 9.8 6.3 2.3 8.5 2.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Pyr_redox PF00070.22 EXF84254.1 - 3.3e-13 49.8 0.1 9.2e-13 48.4 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF84254.1 - 2.3e-08 34.3 0.1 0.00022 21.3 0.0 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF84254.1 - 1.5e-07 31.5 0.0 0.011 15.6 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF84254.1 - 0.0001 21.3 0.0 0.0002 20.3 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 EXF84254.1 - 0.0041 16.1 0.0 0.0069 15.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.19 EXF84254.1 - 0.035 12.9 0.2 0.072 11.9 0.1 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EXF84254.1 - 0.052 12.1 0.1 5.4 5.5 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase NAD_binding_9 PF13454.1 EXF84254.1 - 0.072 12.8 0.5 14 5.4 0.0 3.1 2 1 0 3 3 3 0 FAD-NAD(P)-binding HI0933_like PF03486.9 EXF84254.1 - 0.11 10.9 0.2 0.93 7.8 0.1 2.0 2 0 0 2 2 2 0 HI0933-like protein PI-PLC-X PF00388.14 EXF84255.1 - 8.3e-58 193.9 0.0 1.6e-57 192.9 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EXF84255.1 - 3.7e-38 130.1 0.1 1.1e-37 128.6 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EXF84255.1 - 7.2e-11 41.7 0.3 7.3e-10 38.5 0.1 2.4 2 0 0 2 2 2 1 C2 domain EF-hand_like PF09279.6 EXF84255.1 - 0.0041 17.1 0.0 0.012 15.6 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like TFIIA PF03153.8 EXF84255.1 - 2 8.2 12.4 0.3 10.9 4.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DHDPS PF00701.17 EXF84256.1 - 7.9e-46 155.9 0.0 9.4e-46 155.7 0.0 1.1 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Pkinase PF00069.20 EXF84257.1 - 3e-46 157.6 0.0 5.6e-46 156.8 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF84257.1 - 4.3e-28 98.0 0.0 6.4e-28 97.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF84257.1 - 0.077 11.9 0.1 1.6 7.6 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Clr5 PF14420.1 EXF84258.1 - 2e-19 69.1 3.8 4.1e-19 68.2 2.6 1.5 1 0 0 1 1 1 1 Clr5 domain TPR_12 PF13424.1 EXF84258.1 - 0.0021 17.9 7.8 0.4 10.6 0.6 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat FAD_binding_6 PF00970.19 EXF84258.1 - 0.011 15.8 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain TPR_1 PF00515.23 EXF84258.1 - 0.018 14.6 0.0 9.6 5.9 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.1 EXF84258.1 - 0.039 13.7 3.0 18 5.4 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EXF84258.1 - 0.041 13.8 0.1 15 5.7 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EXF84258.1 - 0.062 12.9 1.1 1.3 8.6 0.1 2.6 2 0 0 2 2 2 0 TPR repeat Apc3 PF12895.2 EXF84258.1 - 0.074 13.2 1.8 0.64 10.1 0.1 2.8 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4054 PF13262.1 EXF84258.1 - 0.077 13.2 0.7 0.22 11.7 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4054) TPR_19 PF14559.1 EXF84258.1 - 0.31 11.4 2.1 1.7 9.0 0.0 2.9 2 1 2 4 4 4 0 Tetratricopeptide repeat SAP PF02037.22 EXF84260.1 - 4e-12 45.3 0.3 7.1e-12 44.5 0.2 1.4 1 0 0 1 1 1 1 SAP domain Mitofilin PF09731.4 EXF84260.1 - 0.036 12.7 10.3 0.041 12.5 7.2 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein HeH PF12949.2 EXF84260.1 - 0.076 12.5 0.2 0.18 11.3 0.2 1.6 1 0 0 1 1 1 0 HeH/LEM domain Med3 PF11593.3 EXF84260.1 - 0.57 9.3 10.5 0.7 9.0 7.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2413 PF10310.4 EXF84260.1 - 1.3 7.7 13.2 1.9 7.2 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) MCPVI PF02993.9 EXF84260.1 - 3.7 7.6 9.2 5 7.2 6.4 1.3 1 0 0 1 1 1 0 Minor capsid protein VI Metallophos PF00149.23 EXF84261.1 - 4.2e-15 55.6 0.1 6.3e-15 55.1 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EXF84261.1 - 1.1e-05 25.3 0.1 2e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain GST_N_3 PF13417.1 EXF84263.1 - 6.6e-14 51.9 0.0 1.3e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EXF84263.1 - 2.4e-12 46.8 0.0 6.3e-12 45.4 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EXF84263.1 - 5.3e-12 45.5 0.0 1.1e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EXF84263.1 - 7.2e-09 35.4 0.2 2.9e-08 33.4 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EXF84263.1 - 9.3e-08 31.9 0.0 4.5e-07 29.7 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EXF84263.1 - 5.3e-07 30.0 0.2 8.7e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain zf-CCHC PF00098.18 EXF84264.1 - 1.3e-11 43.7 9.7 1.9e-05 24.3 0.4 2.4 2 0 0 2 2 2 2 Zinc knuckle KH_1 PF00013.24 EXF84264.1 - 3.2e-08 33.1 0.2 5.7e-08 32.2 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.1 EXF84264.1 - 1.3e-06 28.0 6.3 0.00046 19.8 2.3 2.5 1 1 1 2 2 2 2 Zinc knuckle KH_3 PF13014.1 EXF84264.1 - 5.1e-05 22.8 0.2 0.00012 21.6 0.2 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_6 PF15288.1 EXF84264.1 - 0.00034 20.2 6.6 0.1 12.2 0.2 2.7 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.1 EXF84264.1 - 0.0012 18.4 6.0 0.29 10.8 0.5 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_2 PF13696.1 EXF84264.1 - 0.085 12.3 6.5 0.12 11.8 0.1 2.9 1 1 1 2 2 2 0 Zinc knuckle Peptidase_M16_C PF05193.16 EXF84264.1 - 0.95 9.1 3.0 8.3 6.0 0.0 2.9 3 0 0 3 3 3 0 Peptidase M16 inactive domain Peptidase_M28 PF04389.12 EXF84265.1 - 1.1e-33 116.4 0.0 2.1e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EXF84265.1 - 0.006 16.1 0.0 0.01 15.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Med11 PF10280.4 EXF84266.1 - 4.1e-31 107.4 0.1 5.3e-31 107.0 0.0 1.2 1 0 0 1 1 1 1 Mediator complex protein Mst1_SARAH PF11629.3 EXF84266.1 - 0.046 13.5 1.0 0.39 10.5 0.0 2.5 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 DUF4266 PF14086.1 EXF84266.1 - 0.13 12.7 2.9 0.37 11.3 2.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4266) WD40 PF00400.27 EXF84267.1 - 2.9e-54 179.0 20.7 1.1e-09 37.8 0.4 6.8 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EXF84267.1 - 2.3e-41 141.1 0.8 3.2e-41 140.7 0.5 1.2 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 EXF84267.1 - 5.7e-06 25.8 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 LisH eIF2A PF08662.6 EXF84267.1 - 7.3e-06 25.8 0.1 0.0015 18.2 0.0 3.4 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EXF84267.1 - 1.3e-05 24.1 0.2 2.4 6.8 0.0 3.9 2 2 1 4 4 4 3 Nup133 N terminal like Nup160 PF11715.3 EXF84267.1 - 0.0013 16.9 3.3 1.6 6.7 0.1 3.2 2 1 0 3 3 3 3 Nucleoporin Nup120/160 AsnC_trans_reg PF01037.16 EXF84267.1 - 0.08 12.6 0.1 0.48 10.1 0.0 2.3 2 0 0 2 2 2 0 AsnC family Vps5 PF09325.5 EXF84268.1 - 2.9e-87 291.8 6.5 3.8e-87 291.4 4.5 1.1 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EXF84268.1 - 9.8e-24 83.3 0.0 2.1e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR_2 PF10455.4 EXF84268.1 - 0.00045 19.2 2.3 0.00085 18.3 1.6 1.5 1 0 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking BAR PF03114.13 EXF84268.1 - 0.0023 17.4 4.7 0.0036 16.8 3.3 1.3 1 0 0 1 1 1 1 BAR domain BAR_3_WASP_bdg PF10456.4 EXF84268.1 - 0.0047 16.2 0.8 0.037 13.3 0.5 2.1 1 1 0 1 1 1 1 WASP-binding domain of Sorting nexin protein Cortex-I_coil PF09304.5 EXF84268.1 - 7.5 6.6 9.6 2.6 8.1 3.9 2.3 2 1 0 2 2 2 0 Cortexillin I, coiled coil Ribosomal_L31 PF01197.13 EXF84269.1 - 0.00081 19.3 0.1 0.011 15.7 0.0 2.3 2 0 0 2 2 2 1 Ribosomal protein L31 Trefoil PF00088.13 EXF84270.1 - 0.23 11.0 6.8 1.2 8.8 0.2 2.3 2 0 0 2 2 2 0 Trefoil (P-type) domain HSP90 PF00183.13 EXF84271.1 - 1.5e-253 842.0 32.3 1.8e-253 841.8 22.4 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.21 EXF84271.1 - 1.3e-11 44.1 0.1 2.4e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EXF84271.1 - 1.4e-10 40.9 0.2 1.4e-10 40.9 0.1 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase LOH1CR12 PF10158.4 EXF84271.1 - 0.017 14.9 0.3 0.066 13.0 0.2 2.0 1 0 0 1 1 1 0 Tumour suppressor protein PVL_ORF50 PF07768.6 EXF84271.1 - 4.4 7.3 11.8 0.5 10.3 2.7 2.7 2 0 0 2 2 2 0 PVL ORF-50-like family Bac_rhamnosid PF05592.6 EXF84273.1 - 8.8e-13 47.2 2.2 7.9e-12 44.1 2.5 1.8 2 1 0 2 2 2 1 Bacterial alpha-L-rhamnosidase Trehalase PF01204.13 EXF84273.1 - 0.0084 14.7 0.2 0.012 14.2 0.1 1.1 1 0 0 1 1 1 1 Trehalase Methyltransf_11 PF08241.7 EXF84274.1 - 0.012 16.1 0.0 0.029 14.8 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_8 PF05148.10 EXF84274.1 - 0.31 10.6 0.0 0.52 9.8 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase F-box PF00646.28 EXF84276.1 - 5.8e-07 29.0 0.3 1.3e-06 27.8 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EXF84276.1 - 1.3e-05 24.8 0.0 3.1e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 F-box-like Tom37 PF10568.4 EXF84277.1 - 4.9e-21 74.7 0.1 9.6e-21 73.8 0.1 1.5 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Tom37_C PF11801.3 EXF84277.1 - 5.1e-20 72.0 0.0 7.2e-20 71.5 0.0 1.2 1 0 0 1 1 1 1 Tom37 C-terminal domain GST_C_2 PF13410.1 EXF84277.1 - 0.0053 16.6 0.0 0.02 14.7 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EXF84277.1 - 0.017 15.5 0.0 0.11 12.9 0.0 2.3 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain PIG-U PF06728.8 EXF84278.1 - 1e-124 416.2 26.5 1.2e-124 416.0 18.4 1.0 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Pescadillo_N PF06732.6 EXF84279.1 - 3.4e-113 377.5 0.1 3.4e-113 377.5 0.0 1.9 2 1 0 2 2 2 1 Pescadillo N-terminus BRCT PF00533.21 EXF84279.1 - 5.6e-09 36.0 0.0 1.9e-08 34.3 0.0 2.0 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RRN9 PF10680.4 EXF84280.1 - 4.1e-16 58.4 0.3 4.1e-16 58.4 0.2 2.4 3 0 0 3 3 3 1 RNA polymerase I specific transcription initiation factor zf-C2H2_4 PF13894.1 EXF84280.1 - 0.066 13.5 0.1 0.21 11.9 0.1 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger FAD-oxidase_C PF02913.14 EXF84281.1 - 1.6e-60 204.5 1.5 6.1e-60 202.6 0.3 2.0 2 0 0 2 2 2 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EXF84281.1 - 8e-38 129.0 0.0 1.7e-37 127.9 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Clr5 PF14420.1 EXF84282.1 - 1.2e-19 69.9 1.2 3.7e-19 68.3 0.4 2.2 2 0 0 2 2 2 1 Clr5 domain ECH PF00378.15 EXF84283.1 - 5.4e-38 130.5 0.0 6.8e-38 130.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family SPRY PF00622.23 EXF84284.1 - 5.6e-06 26.4 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 SPRY domain Na_Ca_ex PF01699.19 EXF84285.1 - 1.1e-39 135.2 32.1 4.4e-22 78.2 9.5 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Pkinase PF00069.20 EXF84286.1 - 1.5e-64 217.6 0.0 3e-64 216.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF84286.1 - 5.5e-37 127.2 0.0 1.9e-31 109.0 0.0 2.5 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 EXF84286.1 - 9.2e-06 24.8 0.0 0.011 14.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EXF84286.1 - 0.00087 19.0 0.0 0.0019 17.9 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EXF84286.1 - 0.0068 15.7 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EXF84286.1 - 0.019 14.0 0.0 0.034 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GWT1 PF06423.7 EXF84287.1 - 7.4e-45 152.3 2.7 2e-44 151.0 1.9 1.8 1 0 0 1 1 1 1 GWT1 TT_ORF1 PF02956.9 EXF84287.1 - 0.23 9.8 0.0 0.32 9.4 0.0 1.1 1 0 0 1 1 1 0 TT viral orf 1 GTP_EFTU_D2 PF03144.20 EXF84289.1 - 0.067 13.3 0.0 0.12 12.5 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu domain 2 Pkinase PF00069.20 EXF84290.1 - 1.5e-59 201.2 0.0 2.1e-59 200.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF84290.1 - 9.7e-33 113.3 0.0 2.6e-31 108.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EXF84290.1 - 0.012 14.4 0.0 0.017 13.9 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase HSP70 PF00012.15 EXF84291.1 - 1.2e-10 40.0 0.1 8.8e-10 37.1 0.0 1.9 2 0 0 2 2 2 1 Hsp70 protein DUF2439 PF10382.4 EXF84291.1 - 0.04 14.1 0.1 1.5 9.0 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2439) Arch_ATPase PF01637.13 EXF84293.1 - 4.5e-06 26.5 0.2 7.1e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_16 PF13191.1 EXF84293.1 - 5.3e-06 26.5 1.3 0.00061 19.8 0.5 2.7 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.8 EXF84293.1 - 0.0017 17.3 0.0 0.0037 16.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 EXF84293.1 - 0.0072 15.7 0.1 0.04 13.3 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EXF84293.1 - 0.051 13.1 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Pex14_N PF04695.8 EXF84293.1 - 0.067 13.2 0.1 0.12 12.4 0.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Gtr1_RagA PF04670.7 EXF84293.1 - 0.098 11.7 0.1 0.68 9.0 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region Fungal_trans_2 PF11951.3 EXF84294.1 - 6.5e-26 90.8 1.9 8.7e-15 54.1 0.2 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF84294.1 - 7.3e-09 35.3 12.2 1.4e-08 34.4 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain AT_hook PF02178.14 EXF84294.1 - 0.17 11.6 7.3 0.17 11.6 3.7 2.2 2 0 0 2 2 2 0 AT hook motif Peptidase_M20 PF01546.23 EXF84295.1 - 4e-24 85.1 0.1 7.1e-24 84.3 0.1 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EXF84295.1 - 1.4e-12 47.3 0.0 4.7e-12 45.6 0.0 2.0 2 1 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EXF84295.1 - 0.0039 16.9 0.0 0.0072 16.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 ABC_tran PF00005.22 EXF84296.1 - 2.5e-50 170.3 0.0 9.1e-24 84.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane PF01061.19 EXF84296.1 - 4.5e-50 169.7 32.5 4.3e-28 97.9 7.5 3.0 3 0 0 3 3 3 2 ABC-2 type transporter AAA_21 PF13304.1 EXF84296.1 - 2.7e-19 70.2 5.0 1.5e-08 34.9 0.4 4.2 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EXF84296.1 - 5.5e-10 39.5 0.3 0.0014 18.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EXF84296.1 - 7.5e-10 38.2 0.5 0.00046 19.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_15 PF13175.1 EXF84296.1 - 7.9e-10 38.3 0.0 0.036 13.1 0.0 4.1 4 0 0 4 4 4 3 AAA ATPase domain SMC_N PF02463.14 EXF84296.1 - 4e-09 36.0 0.6 0.00022 20.5 0.0 3.7 2 2 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EXF84296.1 - 1.5e-08 34.0 1.5 0.003 17.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EXF84296.1 - 6.9e-08 33.0 2.3 0.00045 20.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EXF84296.1 - 9.8e-07 28.9 0.0 0.13 12.4 0.0 3.5 3 0 0 3 3 3 2 AAA domain PDR_CDR PF06422.7 EXF84296.1 - 3.4e-06 26.6 0.0 8.8e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 CDR ABC transporter AAA_17 PF13207.1 EXF84296.1 - 3.6e-06 27.7 0.0 0.027 15.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EXF84296.1 - 4.7e-06 26.1 1.3 0.022 14.1 0.0 3.3 5 0 0 5 5 3 2 AAA domain AAA_28 PF13521.1 EXF84296.1 - 6.9e-06 26.1 0.7 0.012 15.6 0.2 2.6 2 0 0 2 2 2 2 AAA domain T2SE PF00437.15 EXF84296.1 - 1e-05 24.6 0.1 0.087 11.7 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_18 PF13238.1 EXF84296.1 - 1.2e-05 25.5 0.0 0.034 14.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EXF84296.1 - 2.4e-05 24.0 0.0 0.18 11.4 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_10 PF12846.2 EXF84296.1 - 8.2e-05 22.1 2.7 0.038 13.4 0.1 2.4 2 0 0 2 2 2 2 AAA-like domain AAA_19 PF13245.1 EXF84296.1 - 0.00011 21.8 0.1 0.065 12.9 0.0 2.7 2 0 0 2 2 2 1 Part of AAA domain SbcCD_C PF13558.1 EXF84296.1 - 0.00011 21.9 1.4 0.3 11.0 0.1 3.7 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit Arch_ATPase PF01637.13 EXF84296.1 - 0.00016 21.4 0.0 0.16 11.6 0.0 2.3 2 0 0 2 2 2 1 Archaeal ATPase PDR_assoc PF08370.6 EXF84296.1 - 0.00019 20.8 0.1 0.0011 18.3 0.0 2.3 2 0 0 2 2 2 1 Plant PDR ABC transporter associated MMR_HSR1 PF01926.18 EXF84296.1 - 0.00022 21.1 1.3 0.2 11.6 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EXF84296.1 - 0.00029 20.3 1.1 0.081 12.3 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_30 PF13604.1 EXF84296.1 - 0.00049 19.7 0.1 0.81 9.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EXF84296.1 - 0.00061 19.2 3.0 0.41 10.0 0.3 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 EXF84296.1 - 0.00077 19.0 0.1 0.67 9.4 0.0 2.4 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 EXF84296.1 - 0.00098 18.6 0.2 0.37 10.2 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.1 EXF84296.1 - 0.0016 18.0 0.7 1.9 8.0 0.1 2.5 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 EXF84296.1 - 0.0016 18.9 0.4 4 7.9 0.0 3.2 3 0 0 3 3 3 0 Miro-like protein AAA_33 PF13671.1 EXF84296.1 - 0.0025 17.7 0.0 3 7.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EXF84296.1 - 0.0042 17.2 0.1 4 7.6 0.0 2.9 3 0 0 3 3 2 0 RNA helicase UPF0079 PF02367.12 EXF84296.1 - 0.0046 16.5 0.2 2.8 7.5 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 MobB PF03205.9 EXF84296.1 - 0.0064 16.1 0.1 1.8 8.3 0.0 2.4 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Pox_A32 PF04665.7 EXF84296.1 - 0.0072 15.6 0.7 0.24 10.6 0.1 2.3 2 0 0 2 2 2 1 Poxvirus A32 protein ABC_ATPase PF09818.4 EXF84296.1 - 0.011 14.3 0.5 0.48 8.9 0.2 3.1 3 0 0 3 3 3 0 Predicted ATPase of the ABC class KAP_NTPase PF07693.9 EXF84296.1 - 0.012 14.6 0.0 0.22 10.4 0.0 2.2 2 0 0 2 2 2 0 KAP family P-loop domain NTPase_1 PF03266.10 EXF84296.1 - 0.012 15.3 0.2 1.9 8.2 0.0 3.4 4 0 0 4 4 4 0 NTPase AAA_14 PF13173.1 EXF84296.1 - 0.015 15.2 0.1 6.3 6.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EXF84296.1 - 0.02 14.0 0.5 4.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Septin PF00735.13 EXF84296.1 - 0.02 13.8 0.2 0.63 9.0 0.0 2.3 2 0 0 2 2 2 0 Septin IstB_IS21 PF01695.12 EXF84296.1 - 0.026 13.9 0.4 3.8 6.8 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_5 PF07728.9 EXF84296.1 - 0.032 13.9 0.4 11 5.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.20 EXF84296.1 - 0.042 13.3 0.0 2 7.8 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SRPRB PF09439.5 EXF84296.1 - 0.043 13.0 0.7 6.8 5.8 0.0 2.4 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit Nbl1_Borealin_N PF10444.4 EXF84296.1 - 0.059 12.7 0.0 1.1 8.7 0.0 2.4 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal PRK PF00485.13 EXF84296.1 - 0.062 12.8 0.2 2.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Dynamin_N PF00350.18 EXF84296.1 - 0.14 11.9 1.4 5.1 6.8 0.1 2.6 2 0 0 2 2 2 0 Dynamin family PhoH PF02562.11 EXF84296.1 - 0.18 10.9 0.1 6.8 5.8 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.4 EXF84296.1 - 0.4 9.5 0.1 10 4.9 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) DUF87 PF01935.12 EXF84296.1 - 0.4 10.4 2.8 0.62 9.8 0.6 2.3 2 0 0 2 2 1 0 Domain of unknown function DUF87 ABC2_membrane_3 PF12698.2 EXF84296.1 - 1.6 7.6 26.3 1 8.3 9.7 2.5 2 0 0 2 2 2 0 ABC-2 family transporter protein Glyco_hydro_43 PF04616.9 EXF84297.1 - 4.7e-49 167.0 3.6 5.7e-49 166.7 2.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF377 PF04041.8 EXF84297.1 - 0.065 11.9 0.0 0.12 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF377) E1-E2_ATPase PF00122.15 EXF84298.1 - 2.9e-66 222.7 2.1 2.9e-66 222.7 1.4 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EXF84298.1 - 7.8e-32 110.2 7.5 7.8e-32 110.2 5.2 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EXF84298.1 - 2.4e-31 109.8 0.0 8.1e-30 104.8 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EXF84298.1 - 6.9e-19 67.5 0.0 1.4e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EXF84298.1 - 3e-15 56.8 0.0 1e-14 55.1 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EXF84298.1 - 3.2e-14 52.1 0.1 3.2e-14 52.1 0.1 2.1 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EXF84298.1 - 0.00026 20.6 0.1 0.0017 18.0 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Exo_endo_phos PF03372.18 EXF84299.1 - 5.7e-17 62.4 0.1 8.9e-17 61.8 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ADH_zinc_N PF00107.21 EXF84301.1 - 3.1e-27 94.6 0.2 4.7e-27 94.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF84301.1 - 2.9e-18 67.0 0.0 1.8e-17 64.3 0.0 2.2 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF84301.1 - 4.1e-11 42.6 0.0 1.8e-10 40.5 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain AlaDh_PNT_C PF01262.16 EXF84301.1 - 0.0059 16.1 1.2 0.014 15.0 0.4 1.8 1 1 1 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EXF84301.1 - 0.11 12.5 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain ELFV_dehydrog PF00208.16 EXF84301.1 - 1.1 8.7 4.5 0.68 9.4 0.3 2.4 2 1 1 3 3 3 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Glyco_hydro_12 PF01670.11 EXF84302.1 - 1.8e-20 73.2 1.3 2.9e-20 72.6 0.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 12 PhzC-PhzF PF02567.11 EXF84303.1 - 3.8e-45 154.2 0.3 1.1e-44 152.7 0.2 1.7 1 1 0 1 1 1 1 Phenazine biosynthesis-like protein PALP PF00291.20 EXF84304.1 - 4.4e-52 177.2 0.8 7.2e-52 176.5 0.6 1.3 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_M20 PF01546.23 EXF84304.1 - 2.8e-26 92.1 0.0 5.4e-26 91.2 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EXF84304.1 - 1.1e-16 60.6 0.0 2.5e-16 59.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EXF84304.1 - 0.055 13.2 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 Peptidase family M28 RrnaAD PF00398.15 EXF84306.1 - 1.2e-06 27.7 0.0 3.9e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Sigma54_CBD PF04963.8 EXF84306.1 - 0.1 11.9 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain Glyco_transf_90 PF05686.7 EXF84307.1 - 4.1e-12 45.4 7.5 9.6e-11 40.9 0.0 2.6 3 0 0 3 3 3 2 Glycosyl transferase family 90 Arginase PF00491.16 EXF84308.1 - 9.2e-75 251.4 0.1 1.1e-74 251.2 0.1 1.0 1 0 0 1 1 1 1 Arginase family MARVEL PF01284.18 EXF84309.1 - 2.8e-07 30.4 17.1 5.4e-07 29.5 11.8 1.5 1 1 0 1 1 1 1 Membrane-associating domain DUF3733 PF12534.3 EXF84309.1 - 0.37 10.1 9.8 0.59 9.4 4.9 2.5 1 1 1 2 2 2 0 Leucine-rich repeat containing protein 8 DUF3671 PF12420.3 EXF84309.1 - 1.1 9.2 5.3 1.6 8.7 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function Microtub_assoc PF07989.6 EXF84311.1 - 2.9e-19 68.6 9.0 2.9e-19 68.6 6.3 7.1 8 1 0 8 8 8 1 Microtubule associated Mto2_bdg PF12808.2 EXF84311.1 - 1.2e-12 47.7 9.3 1.2e-12 47.7 6.4 13.1 14 1 1 15 15 15 2 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF1479 PF07350.7 EXF84312.1 - 2.2e-162 540.3 0.0 2.5e-162 540.1 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1479) PhyH PF05721.8 EXF84312.1 - 0.096 12.7 0.2 7.9 6.4 0.0 2.3 2 0 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) Methyltransf_31 PF13847.1 EXF84313.1 - 8.3e-07 28.7 0.0 1.1e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF84313.1 - 1.6e-05 25.3 0.0 2.5e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF84313.1 - 0.0056 17.1 0.0 0.0083 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF84313.1 - 0.06 13.3 0.0 0.12 12.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EXF84313.1 - 0.12 12.0 0.0 0.28 10.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain DUF1993 PF09351.5 EXF84314.1 - 1.1e-48 165.1 0.0 1.3e-48 164.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1993) DUF2235 PF09994.4 EXF84315.1 - 4.7e-103 344.3 0.5 7.2e-103 343.7 0.4 1.3 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) AATF-Che1 PF13339.1 EXF84315.1 - 0.093 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor An_peroxidase PF03098.10 EXF84316.1 - 1.4e-97 327.3 0.0 4.1e-95 319.1 0.0 2.1 1 1 0 1 1 1 1 Animal haem peroxidase p450 PF00067.17 EXF84316.1 - 5e-06 25.2 0.1 1.8e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 GMC_oxred_N PF00732.14 EXF84317.1 - 7.7e-33 113.9 0.0 1.5e-32 112.9 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF84317.1 - 5.2e-21 75.4 0.6 1.7e-20 73.7 0.3 1.9 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EXF84317.1 - 1.5e-05 24.0 6.9 0.00027 19.9 4.7 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EXF84317.1 - 4.1e-05 22.2 1.7 0.0002 19.9 0.8 2.0 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EXF84317.1 - 5.1e-05 22.2 6.8 0.00033 19.6 4.7 2.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EXF84317.1 - 0.00035 20.5 0.5 0.00035 20.5 0.3 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EXF84317.1 - 0.013 14.6 0.2 0.05 12.6 0.3 1.8 2 0 0 2 2 2 0 Thi4 family FAD_oxidored PF12831.2 EXF84317.1 - 0.014 14.4 1.7 0.037 13.1 0.5 1.9 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EXF84317.1 - 0.019 14.0 0.4 0.036 13.1 0.3 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EXF84317.1 - 0.027 13.4 0.2 0.043 12.7 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox PF00070.22 EXF84317.1 - 0.14 12.6 1.4 0.6 10.5 0.3 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Crystall_3 PF08964.5 EXF84318.1 - 0.0016 18.0 0.0 0.79 9.4 0.0 2.1 2 0 0 2 2 2 2 Beta/Gamma crystallin Crystall PF00030.14 EXF84318.1 - 0.039 13.8 0.1 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Beta/Gamma crystallin Pyr_redox PF00070.22 EXF84319.1 - 4.5e-13 49.4 0.5 5.2e-11 42.7 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF84319.1 - 1.7e-10 41.1 0.0 0.011 15.6 0.0 4.1 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF84319.1 - 1.5e-05 25.1 0.0 0.004 17.2 0.0 2.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF84319.1 - 3.2e-05 23.0 0.0 5.3e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 EXF84319.1 - 0.0032 16.4 0.0 0.11 11.4 0.0 2.4 1 1 1 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.1 EXF84319.1 - 0.0033 17.6 0.0 0.69 10.1 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding DAO PF01266.19 EXF84319.1 - 0.0042 16.0 0.2 0.45 9.3 0.0 2.7 3 0 0 3 3 3 1 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EXF84319.1 - 0.017 13.7 0.2 3.2 6.2 0.0 2.4 2 1 1 3 3 3 0 Tryptophan halogenase Mqo PF06039.10 EXF84319.1 - 0.052 11.7 0.0 0.073 11.2 0.0 1.1 1 0 0 1 1 1 0 Malate:quinone oxidoreductase (Mqo) Ank_2 PF12796.2 EXF84320.1 - 1.6e-45 153.3 1.2 2.5e-12 46.9 0.0 4.3 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EXF84320.1 - 8.4e-36 120.0 13.2 1.8e-06 27.4 0.0 9.5 11 0 0 11 11 11 6 Ankyrin repeat Ank_4 PF13637.1 EXF84320.1 - 3.9e-28 97.3 7.3 8.9e-11 42.0 0.0 7.6 2 2 6 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF84320.1 - 6.5e-28 93.9 0.5 0.00026 20.9 0.0 7.3 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 EXF84320.1 - 2.6e-25 87.8 11.1 2.9e-07 30.5 0.0 7.5 1 1 7 8 8 8 7 Ankyrin repeats (many copies) RVP PF00077.15 EXF84320.1 - 0.12 12.2 0.0 9.9 6.1 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease Glyco_hydro_43 PF04616.9 EXF84321.1 - 2.7e-48 164.4 8.4 2.7e-48 164.4 5.8 1.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 CBM_6 PF03422.10 EXF84321.1 - 5.6e-35 120.2 2.2 5.6e-35 120.2 1.5 1.9 2 0 0 2 2 2 1 Carbohydrate binding module (family 6) Glyco_hydro_32N PF00251.15 EXF84321.1 - 0.0018 17.6 7.0 0.0028 17.0 4.4 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain HLH PF00010.21 EXF84323.1 - 1.2e-12 47.2 0.2 2.8e-12 46.1 0.1 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain DUF605 PF04652.11 EXF84323.1 - 9.3 5.5 45.4 2.7 7.3 9.3 2.2 2 0 0 2 2 2 0 Vta1 like Aldedh PF00171.17 EXF84324.1 - 4.1e-105 351.7 0.1 5.2e-105 351.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family PhoD PF09423.5 EXF84325.1 - 2.1e-08 33.1 0.3 3.4e-06 25.8 0.0 2.4 2 0 0 2 2 2 2 PhoD-like phosphatase Ank_2 PF12796.2 EXF84326.1 - 7.2e-92 301.8 22.4 8.3e-21 74.1 0.2 5.2 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EXF84326.1 - 4.8e-55 180.7 27.3 1.4e-09 37.2 0.2 11.4 10 2 0 10 10 10 9 Ankyrin repeat Ank_4 PF13637.1 EXF84326.1 - 1.4e-44 149.7 12.5 1.5e-12 47.6 0.1 8.5 2 1 7 9 9 9 9 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF84326.1 - 3.5e-42 141.4 15.8 6.4e-12 45.3 0.5 6.9 5 1 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF84326.1 - 1.8e-41 135.9 7.5 6.1e-06 25.9 0.0 10.5 10 1 0 10 10 10 7 Ankyrin repeat RVP PF00077.15 EXF84326.1 - 0.032 14.1 1.6 5.7 6.9 0.0 2.9 3 1 0 3 3 3 0 Retroviral aspartyl protease DUF1843 PF08898.5 EXF84326.1 - 0.12 12.4 8.7 0.54 10.3 0.1 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1843) DUF3416 PF11896.3 EXF84326.1 - 1.2 9.0 7.6 14 5.5 0.1 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF3416) Per1 PF04080.8 EXF84327.1 - 1.1e-102 343.0 3.2 1.3e-102 342.7 2.2 1.1 1 0 0 1 1 1 1 Per1-like CitMHS PF03600.11 EXF84327.1 - 0.21 10.1 3.4 0.054 12.0 0.3 1.4 2 0 0 2 2 2 0 Citrate transporter DUF4131 PF13567.1 EXF84327.1 - 6.9 6.0 12.2 3.5 7.0 2.6 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DUF1772 PF08592.6 EXF84328.1 - 0.0025 17.5 1.6 0.0044 16.7 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF2085 PF09858.4 EXF84328.1 - 0.1 12.7 0.6 0.21 11.7 0.1 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) Methyltransf_23 PF13489.1 EXF84329.1 - 5.5e-20 71.6 0.0 8.3e-20 71.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF84329.1 - 2.8e-10 40.0 0.0 1.9e-09 37.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF84329.1 - 7.9e-10 39.3 0.0 1.8e-08 34.9 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF84329.1 - 3.4e-07 30.6 0.0 1.7e-06 28.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF84329.1 - 1.4e-06 28.6 0.0 2.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF84329.1 - 8e-05 22.9 0.0 0.00019 21.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF84329.1 - 0.0025 16.8 0.0 0.0064 15.5 0.0 1.8 2 0 0 2 2 2 1 Putative methyltransferase MTS PF05175.9 EXF84329.1 - 0.051 12.9 0.0 0.099 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain PCMT PF01135.14 EXF84329.1 - 0.076 12.5 0.0 1.2 8.6 0.0 2.1 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EXF84329.1 - 0.095 11.7 0.0 0.26 10.3 0.0 1.7 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EXF84329.1 - 0.11 12.4 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 EXF84330.1 - 3.2e-22 78.9 0.0 4.8e-22 78.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF84330.1 - 4.3e-10 40.1 0.0 2.8e-09 37.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF84330.1 - 8.7e-08 31.8 0.0 0.00021 20.9 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.7 EXF84330.1 - 1.2e-06 28.9 0.0 1.3e-05 25.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF84330.1 - 1.7e-05 25.2 0.0 0.002 18.5 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF84330.1 - 8e-05 22.9 0.0 0.0013 19.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF84330.1 - 0.018 14.3 0.0 0.36 10.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_26 PF13659.1 EXF84330.1 - 0.027 14.5 0.0 0.15 12.1 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain CheR PF01739.13 EXF84330.1 - 0.081 12.1 0.0 0.14 11.4 0.0 1.3 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain Ubie_methyltran PF01209.13 EXF84330.1 - 0.14 11.2 0.0 17 4.3 0.0 2.8 3 0 0 3 3 3 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EXF84330.1 - 0.19 11.2 0.0 13 5.2 0.0 2.1 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.1 EXF84331.1 - 4.6e-24 84.9 0.0 7.1e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF84331.1 - 3.8e-12 46.7 0.0 1.3e-11 45.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF84331.1 - 2e-11 43.7 0.0 4.7e-11 42.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF84331.1 - 2.6e-10 40.6 0.0 4.3e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF84331.1 - 1.4e-08 35.0 0.0 3.7e-08 33.7 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF84331.1 - 3.9e-07 30.3 0.0 7.4e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF84331.1 - 0.00011 22.1 0.0 0.00074 19.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF84331.1 - 0.00017 21.0 0.0 0.0072 15.7 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EXF84331.1 - 0.0049 16.0 0.0 0.008 15.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EXF84331.1 - 0.0078 15.2 0.0 0.21 10.6 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_2 PF00891.13 EXF84331.1 - 0.019 14.1 0.0 0.04 13.1 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase Ubie_methyltran PF01209.13 EXF84331.1 - 0.023 13.7 0.0 0.33 10.0 0.0 2.3 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EXF84331.1 - 0.029 14.3 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EXF84331.1 - 0.03 13.7 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase adh_short PF00106.20 EXF84332.1 - 5.7e-22 78.4 0.7 1.4e-21 77.1 0.5 1.7 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF84332.1 - 9.4e-21 74.6 0.0 1.9e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase His_Phos_2 PF00328.17 EXF84332.1 - 1.2e-09 38.0 0.4 3.8e-07 29.7 0.0 2.4 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) KR PF08659.5 EXF84332.1 - 2.5e-08 33.8 0.4 1.3e-07 31.4 0.3 2.1 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EXF84332.1 - 0.021 13.7 0.0 0.034 13.0 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TcpQ PF10671.4 EXF84332.1 - 0.051 13.4 0.1 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Toxin co-regulated pilus biosynthesis protein Q Git3 PF11710.3 EXF84333.1 - 8.2e-19 67.9 10.8 1.5e-18 67.1 7.5 1.4 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EXF84333.1 - 2.9e-10 39.7 1.2 1.3e-09 37.7 0.2 2.5 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 EXF84333.1 - 9e-09 34.8 3.3 9e-09 34.8 2.3 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) CFEM PF05730.6 EXF84334.1 - 4.7e-14 51.9 13.3 4.7e-14 51.9 9.2 1.8 2 0 0 2 2 2 1 CFEM domain Gamma-thionin PF00304.15 EXF84334.1 - 0.058 13.4 2.4 0.17 11.9 1.7 1.7 1 0 0 1 1 1 0 Gamma-thionin family Sporozoite_P67 PF05642.6 EXF84334.1 - 0.97 7.2 6.6 1 7.1 4.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Med3 PF11593.3 EXF84334.1 - 6.5 5.8 10.1 8.3 5.5 7.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Zn_clus PF00172.13 EXF84337.1 - 3.2e-09 36.5 8.4 7.8e-09 35.3 5.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF84337.1 - 2.9e-06 26.3 0.2 1.2e-05 24.3 0.1 2.1 1 1 0 1 1 1 1 Fungal specific transcription factor domain DIOX_N PF14226.1 EXF84338.1 - 1.6e-27 96.2 0.1 2.7e-27 95.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EXF84338.1 - 4.2e-20 71.8 0.0 8.8e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EXF84340.1 - 1.2e-30 106.4 33.6 1.2e-30 106.4 23.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF84340.1 - 2.9e-06 26.1 15.5 2.9e-06 26.1 10.8 3.8 2 2 1 3 3 3 1 Sugar (and other) transporter Gly-zipper_Omp PF13488.1 EXF84340.1 - 0.61 9.7 5.9 0.92 9.2 0.8 3.2 2 0 0 2 2 2 0 Glycine zipper Gly-zipper_YMGG PF13441.1 EXF84340.1 - 1.5 8.3 7.5 2.5 7.6 1.9 3.0 2 0 0 2 2 2 0 YMGG-like Gly-zipper ORC4_C PF14629.1 EXF84345.1 - 4.7e-59 199.1 0.0 9.9e-59 198.1 0.0 1.6 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus INCENP_ARK-bind PF03941.10 EXF84345.1 - 2.1e-16 59.5 0.5 2.1e-16 59.5 0.3 2.9 3 0 0 3 3 2 1 Inner centromere protein, ARK binding region AAA_16 PF13191.1 EXF84345.1 - 5.5e-15 55.8 0.2 5.5e-15 55.8 0.1 3.7 3 1 0 3 3 1 1 AAA ATPase domain PHD PF00628.24 EXF84345.1 - 2.4e-10 39.9 5.9 4.6e-10 39.0 4.1 1.5 1 0 0 1 1 1 1 PHD-finger AAA_22 PF13401.1 EXF84345.1 - 1.9e-08 34.5 0.0 7e-08 32.6 0.0 2.0 1 0 0 1 1 1 1 AAA domain PHD_2 PF13831.1 EXF84345.1 - 2.9e-08 32.8 2.2 5.3e-08 32.0 1.5 1.4 1 0 0 1 1 1 1 PHD-finger AAA PF00004.24 EXF84345.1 - 5e-08 33.2 0.0 1.4e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EXF84345.1 - 1.6e-07 31.1 0.0 5.1e-07 29.4 0.0 1.8 1 1 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 EXF84345.1 - 5.2e-06 25.6 0.6 1.8e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 KAP family P-loop domain Arch_ATPase PF01637.13 EXF84345.1 - 5.3e-05 23.0 0.0 5.3e-05 23.0 0.0 2.2 2 0 0 2 2 1 1 Archaeal ATPase NB-ARC PF00931.17 EXF84345.1 - 0.0034 16.3 0.1 0.0065 15.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain FYVE_2 PF02318.11 EXF84345.1 - 0.0044 16.9 1.6 0.0044 16.9 1.1 2.9 3 0 0 3 3 2 1 FYVE-type zinc finger AAA_14 PF13173.1 EXF84345.1 - 0.0052 16.6 0.0 0.015 15.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EXF84345.1 - 0.0081 15.6 0.2 2.6 7.4 0.0 2.3 2 0 0 2 2 2 1 AAA-like domain zf-HC5HC2H PF13771.1 EXF84345.1 - 0.05 13.7 0.6 0.14 12.3 0.4 1.7 1 0 0 1 1 1 0 PHD-like zinc-binding domain AAA_17 PF13207.1 EXF84345.1 - 0.057 14.2 2.1 0.077 13.8 0.0 2.4 2 0 0 2 2 1 0 AAA domain AAA_29 PF13555.1 EXF84345.1 - 0.071 12.6 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ThiS-like PF14453.1 EXF84345.1 - 0.098 12.5 0.5 1 9.2 0.0 2.7 3 0 0 3 3 3 0 ThiS-like ubiquitin PduV-EutP PF10662.4 EXF84345.1 - 0.1 12.0 0.1 0.44 10.0 0.0 1.8 1 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation C1_1 PF00130.17 EXF84345.1 - 0.18 11.5 4.7 0.029 14.0 0.6 1.7 2 0 0 2 2 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EXF84345.1 - 0.64 9.8 2.0 1.2 8.8 1.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Pox_A32 PF04665.7 EXF84345.1 - 0.7 9.1 0.0 1.3 8.2 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein zf-RING_2 PF13639.1 EXF84345.1 - 1.7 8.5 4.7 4.8 7.0 3.3 1.8 1 1 0 1 1 1 0 Ring finger domain C1_3 PF07649.7 EXF84345.1 - 8.7 6.4 4.3 23 5.1 3.0 1.8 1 0 0 1 1 1 0 C1-like domain SMC_N PF02463.14 EXF84346.1 - 3.4e-69 232.4 8.6 1.1e-67 227.4 5.9 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EXF84346.1 - 2.5e-21 75.8 2.4 4.4e-21 75.0 0.2 2.6 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EXF84346.1 - 8e-14 52.2 2.9 3.2e-06 27.3 0.0 3.0 3 0 0 3 3 3 2 AAA domain Reo_sigmaC PF04582.7 EXF84346.1 - 2.6e-06 26.8 39.8 0.00031 20.0 1.4 7.0 3 2 4 8 8 8 3 Reovirus sigma C capsid protein AAA_29 PF13555.1 EXF84346.1 - 7.8e-05 22.1 0.0 0.00018 20.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain GAS PF13851.1 EXF84346.1 - 0.00022 20.4 35.6 0.00035 19.8 4.9 7.7 2 2 2 6 6 6 2 Growth-arrest specific micro-tubule binding ABC_tran PF00005.22 EXF84346.1 - 0.1 12.8 0.0 0.1 12.8 0.0 6.1 4 2 0 4 4 4 0 ABC transporter MOSC PF03473.12 EXF84347.1 - 1.6e-14 53.5 0.0 2.9e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EXF84347.1 - 1.4e-11 44.1 0.0 3.4e-11 42.8 0.0 1.7 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Fungal_trans_2 PF11951.3 EXF84348.1 - 2.8e-11 42.6 1.1 1.4e-10 40.3 0.1 2.1 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF84348.1 - 7.6e-07 28.9 10.0 1.3e-06 28.1 7.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Mob1_phocein PF03637.12 EXF84349.1 - 1.7e-25 89.6 0.3 2.7e-25 89.0 0.2 1.2 1 0 0 1 1 1 1 Mob1/phocein family cobW PF02492.14 EXF84350.1 - 2.7e-44 150.7 0.2 3.7e-44 150.2 0.2 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EXF84350.1 - 0.00043 19.9 0.0 0.00078 19.1 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain ATP_bind_1 PF03029.12 EXF84350.1 - 0.004 16.7 0.4 0.16 11.4 0.0 2.5 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_19 PF13245.1 EXF84350.1 - 0.011 15.4 0.2 0.036 13.7 0.0 1.8 2 0 0 2 2 2 0 Part of AAA domain ArgK PF03308.11 EXF84350.1 - 0.012 14.4 0.7 1.5 7.4 0.0 2.8 3 0 0 3 3 3 0 ArgK protein AAA_23 PF13476.1 EXF84350.1 - 0.021 15.1 0.1 0.048 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EXF84350.1 - 0.027 14.4 0.8 0.065 13.2 0.2 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.1 EXF84350.1 - 0.028 14.7 0.1 0.086 13.1 0.1 1.8 1 0 0 1 1 1 0 AAA domain Miro PF08477.8 EXF84350.1 - 0.034 14.6 0.7 0.84 10.1 0.0 3.1 3 1 0 3 3 3 0 Miro-like protein AAA_22 PF13401.1 EXF84350.1 - 0.034 14.2 0.3 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EXF84350.1 - 0.039 13.6 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Archaeal ATPase Septin PF00735.13 EXF84350.1 - 0.043 12.8 0.6 8.3 5.3 0.0 2.6 2 1 1 3 3 3 0 Septin DUF258 PF03193.11 EXF84350.1 - 0.054 12.6 0.0 0.087 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EXF84350.1 - 0.054 12.9 0.0 0.092 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 EXF84350.1 - 0.061 13.3 0.0 0.17 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.1 EXF84350.1 - 0.068 12.7 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EXF84350.1 - 0.078 13.2 0.9 0.54 10.5 0.0 2.5 3 0 0 3 3 3 0 ABC transporter AAA_14 PF13173.1 EXF84350.1 - 0.089 12.6 0.1 0.33 10.8 0.0 2.0 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.7 EXF84350.1 - 0.14 11.2 0.0 0.26 10.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NOT2_3_5 PF04153.13 EXF84351.1 - 4.3e-32 110.7 0.7 7.3e-32 110.0 0.5 1.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family CUE PF02845.11 EXF84352.1 - 1.3e-12 46.9 0.0 1.9e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 CUE domain TMEM171 PF15471.1 EXF84352.1 - 0.019 13.7 1.0 0.15 10.8 0.1 2.0 2 0 0 2 2 2 0 Transmembrane protein family 171 DOR PF14839.1 EXF84352.1 - 0.11 12.2 6.5 0.18 11.5 4.5 1.3 1 0 0 1 1 1 0 DOR family zf-C2H2 PF00096.21 EXF84353.1 - 2.5e-15 55.8 18.7 9.9e-05 22.4 0.3 4.4 4 1 1 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF84353.1 - 8.4e-14 50.8 14.8 0.00024 21.1 0.2 4.7 5 0 0 5 5 4 3 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EXF84353.1 - 4.7e-09 36.0 18.0 2.2e-05 24.5 0.5 4.5 4 1 1 5 5 5 2 Zinc-finger double domain RRN7 PF11781.3 EXF84353.1 - 0.0045 16.4 3.5 1.5 8.4 0.0 3.9 4 0 0 4 4 4 1 RNA polymerase I-specific transcription initiation factor Rrn7 zf-BED PF02892.10 EXF84353.1 - 0.006 16.3 7.2 0.054 13.2 2.2 2.7 2 1 0 2 2 2 1 BED zinc finger zf-C2H2_jaz PF12171.3 EXF84353.1 - 0.0082 16.2 16.4 0.2 11.8 0.1 4.7 3 1 1 4 4 3 2 Zinc-finger double-stranded RNA-binding zf-CHCC PF10276.4 EXF84353.1 - 0.055 13.3 1.6 0.15 11.8 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger domain zf-C2HC_2 PF13913.1 EXF84353.1 - 0.058 13.0 1.4 0.15 11.7 0.2 2.3 2 0 0 2 2 1 0 zinc-finger of a C2HC-type PyrI_C PF02748.10 EXF84353.1 - 0.065 12.6 0.5 0.14 11.6 0.1 1.7 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-FCS PF06467.9 EXF84353.1 - 0.072 12.7 0.3 0.58 9.8 0.2 2.6 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-LYAR PF08790.6 EXF84353.1 - 0.3 10.8 5.3 2.3 8.0 0.0 3.6 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger zf-H2C2_5 PF13909.1 EXF84353.1 - 0.46 10.8 9.4 17 5.8 0.1 4.2 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-met PF12874.2 EXF84353.1 - 0.62 10.3 11.4 3.3 8.0 0.0 4.3 5 0 0 5 5 4 0 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EXF84353.1 - 0.85 9.7 7.1 3.2 7.9 3.9 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EXF84353.1 - 1 9.3 9.4 1.3 9.0 1.5 3.5 3 0 0 3 3 3 0 C2H2-type zinc finger zf-TRAF PF02176.13 EXF84353.1 - 1.1 9.6 9.7 1.4 9.3 1.5 3.0 1 1 1 3 3 3 0 TRAF-type zinc finger Ank PF00023.25 EXF84354.1 - 6.7e-09 35.1 0.5 4e-06 26.3 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.2 EXF84354.1 - 4.7e-08 33.2 0.2 6.5e-07 29.5 0.1 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EXF84354.1 - 9.9e-07 28.4 0.1 0.00035 20.5 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 EXF84354.1 - 1.8e-05 25.0 0.5 0.001 19.5 0.1 2.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF84354.1 - 2.7e-05 24.2 0.7 0.0014 18.8 0.4 2.8 2 1 1 3 3 3 1 Ankyrin repeats (many copies) WD40 PF00400.27 EXF84356.1 - 5.5e-16 57.7 6.8 1.9e-06 27.5 0.2 5.0 6 0 0 6 6 6 3 WD domain, G-beta repeat PQQ_2 PF13360.1 EXF84356.1 - 0.011 15.2 0.1 0.044 13.2 0.1 2.1 1 1 0 1 1 1 0 PQQ-like domain Pro-kuma_activ PF09286.6 EXF84357.1 - 9.9e-49 165.0 0.2 2.2e-48 163.9 0.1 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EXF84357.1 - 2e-06 27.2 2.0 3.2e-06 26.5 1.4 1.3 1 0 0 1 1 1 1 Subtilase family HTH_Crp_2 PF13545.1 EXF84357.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Complex1_LYR_1 PF13232.1 EXF84358.1 - 1.2e-20 73.4 3.7 1.6e-20 73.0 2.5 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EXF84358.1 - 1.1e-18 66.7 3.3 1.4e-18 66.3 2.3 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 EXF84358.1 - 0.011 16.1 1.1 0.014 15.9 0.8 1.2 1 0 0 1 1 1 0 Complex1_LYR-like DUF3879 PF12995.2 EXF84358.1 - 0.056 13.0 0.2 0.071 12.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3879) Nop14 PF04147.7 EXF84359.1 - 1.3 6.8 11.9 2.4 5.9 8.2 1.3 1 0 0 1 1 1 0 Nop14-like family CBM-like PF14683.1 EXF84360.1 - 5.2e-25 88.0 0.0 1.2e-24 86.8 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EXF84360.1 - 5.8e-20 71.2 1.9 8.1e-20 70.7 0.0 2.3 2 0 0 2 2 2 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EXF84360.1 - 9.9e-07 28.7 3.0 0.00013 21.9 0.1 2.9 3 0 0 3 3 3 2 Carboxypeptidase regulatory-like domain Fungal_trans PF04082.13 EXF84361.1 - 7.4e-13 47.9 0.2 2e-12 46.5 0.2 1.7 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF84361.1 - 0.0019 18.0 8.0 0.0036 17.1 5.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RRM_1 PF00076.17 EXF84363.1 - 8.6e-16 57.3 0.0 1.3e-12 47.1 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF84363.1 - 1.3e-08 34.6 0.0 2.8e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) PsbQ PF05757.6 EXF84364.1 - 0.15 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Ras PF00071.17 EXF84365.1 - 1.8e-51 173.7 0.0 2.2e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EXF84365.1 - 7.2e-21 74.8 0.2 4.9e-20 72.1 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EXF84365.1 - 4.3e-11 42.3 0.0 5.1e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EXF84365.1 - 3.1e-06 26.7 0.2 3e-05 23.5 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EXF84365.1 - 5.5e-05 23.0 0.0 0.0001 22.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EXF84365.1 - 0.0014 17.7 0.0 0.0018 17.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EXF84365.1 - 0.0063 16.6 0.2 0.14 12.2 0.1 2.5 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EXF84365.1 - 0.007 16.3 0.1 0.36 10.7 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain Scytalone_dh PF02982.9 EXF84365.1 - 0.04 13.4 0.0 0.15 11.6 0.0 1.8 2 0 0 2 2 2 0 Scytalone dehydratase AAA_33 PF13671.1 EXF84365.1 - 0.05 13.4 0.0 0.13 12.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EXF84365.1 - 0.07 11.9 0.1 0.15 10.8 0.0 1.6 1 1 0 2 2 2 0 NB-ARC domain DUF258 PF03193.11 EXF84365.1 - 0.1 11.7 0.1 0.17 11.0 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function, DUF258 RGS PF00615.14 EXF84368.1 - 1.2e-37 128.6 0.7 5.7e-37 126.4 0.0 2.5 3 0 0 3 3 3 1 Regulator of G protein signaling domain DEP PF00610.16 EXF84368.1 - 1.1e-25 89.1 0.4 4.7e-21 74.3 0.0 3.5 3 1 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Adeno_E3B PF03376.9 EXF84369.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Adenovirus E3B protein DUF1053 PF06327.9 EXF84369.1 - 0.12 12.7 0.0 0.15 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1053) FMN_dh PF01070.13 EXF84370.1 - 2.9e-88 296.1 1.4 1.9e-48 165.1 0.0 2.1 1 1 1 2 2 2 2 FMN-dependent dehydrogenase IMPDH PF00478.20 EXF84370.1 - 0.0054 15.6 0.0 0.011 14.6 0.0 1.4 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.12 EXF84370.1 - 0.0064 15.4 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EXF84370.1 - 0.015 14.5 0.5 0.43 9.7 0.0 2.5 1 1 2 3 3 3 0 Histidine biosynthesis protein DHO_dh PF01180.16 EXF84370.1 - 0.085 11.8 0.6 0.84 8.5 0.0 2.4 2 1 0 3 3 3 0 Dihydroorotate dehydrogenase Glyco_hydro_35 PF01301.14 EXF84373.1 - 4.9e-83 279.1 0.0 6.5e-83 278.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EXF84373.1 - 2.1e-55 186.9 0.0 3.2e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EXF84373.1 - 6.3e-51 171.3 5.1 4.2e-26 91.3 0.9 2.5 2 0 0 2 2 2 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EXF84373.1 - 3e-15 55.3 0.0 6.3e-15 54.3 0.0 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 DUF1399 PF07173.7 EXF84374.1 - 1.2e-07 32.1 1.8 0.0013 19.0 0.3 3.2 2 1 1 3 3 3 3 Protein of unknown function (DUF1399) Abhydrolase_5 PF12695.2 EXF84375.1 - 5e-05 23.0 0.0 8.7e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF84375.1 - 0.0002 20.6 0.0 0.00037 19.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.4 EXF84375.1 - 0.0012 18.1 0.0 0.0078 15.4 0.0 2.3 2 1 0 2 2 2 1 Esterase PHB depolymerase ADH_zinc_N_2 PF13602.1 EXF84376.1 - 7.1e-23 81.8 0.0 1.3e-22 81.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EXF84376.1 - 3.5e-21 75.1 0.0 1.2e-20 73.3 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF84376.1 - 5.4e-05 22.9 0.0 0.015 15.0 0.0 2.7 2 1 1 3 3 3 2 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 EXF84376.1 - 0.00056 20.4 0.0 0.0035 17.9 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF84376.1 - 0.052 13.1 0.0 0.11 12.0 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain AlaDh_PNT_C PF01262.16 EXF84376.1 - 0.22 11.0 0.9 1.5 8.3 0.6 2.0 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Tannase PF07519.6 EXF84377.1 - 4e-96 322.6 1.1 4.6e-96 322.3 0.8 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase Abhydrolase_6 PF12697.2 EXF84377.1 - 3.7e-08 33.5 0.0 1.8e-07 31.2 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF84377.1 - 2.5e-06 26.8 0.0 0.0061 15.8 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EXF84377.1 - 1.8e-05 24.5 0.4 0.0017 18.1 0.2 2.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF84377.1 - 0.0014 18.2 0.0 0.0034 16.9 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.15 EXF84377.1 - 0.031 13.7 0.0 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Zn_clus PF00172.13 EXF84378.1 - 2.4e-08 33.7 10.0 3.8e-08 33.0 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PseudoU_synth_1 PF01416.15 EXF84379.1 - 2.1e-25 89.1 0.2 7.1e-12 45.6 0.0 3.3 3 1 1 4 4 4 2 tRNA pseudouridine synthase Sigma70_r1_1 PF03979.9 EXF84379.1 - 0.025 14.5 1.2 0.025 14.5 0.8 2.1 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 DUF2852 PF11014.3 EXF84379.1 - 3.6 7.5 7.1 0.97 9.4 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) Med22 PF06179.7 EXF84380.1 - 0.00036 20.5 0.1 0.042 13.8 0.0 2.1 2 0 0 2 2 2 2 Surfeit locus protein 5 subunit 22 of Mediator complex APH PF01636.18 EXF84381.1 - 6.3e-08 32.6 0.0 1.6e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EXF84381.1 - 0.0058 16.2 0.0 0.018 14.5 0.0 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase Fungal_trans PF04082.13 EXF84382.1 - 1.4e-13 50.3 0.0 2.6e-13 49.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans_2 PF11951.3 EXF84384.1 - 3.7e-26 91.6 0.0 4.8e-26 91.2 0.0 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain DIOX_N PF14226.1 EXF84387.1 - 3.8e-12 46.7 0.1 1e-11 45.3 0.0 1.7 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EXF84387.1 - 1.5e-09 37.9 0.0 2.8e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily MFS_1 PF07690.11 EXF84388.1 - 7.5e-36 123.5 38.6 7.5e-36 123.5 26.7 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF84388.1 - 3.9e-12 45.4 26.2 1.3e-09 37.1 12.0 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter ESSS PF10183.4 EXF84388.1 - 0.2 12.0 1.6 0.47 10.8 0.2 2.3 2 0 0 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) FMO-like PF00743.14 EXF84389.1 - 1.3e-30 106.1 0.2 1.8e-15 56.1 0.0 3.0 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EXF84389.1 - 2.7e-14 53.7 0.0 7.5e-14 52.2 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF84389.1 - 6.8e-10 39.1 0.0 5.9e-09 36.1 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF84389.1 - 2.8e-05 23.1 0.2 0.056 12.3 0.0 3.2 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EXF84389.1 - 0.00017 21.3 0.3 0.037 13.8 0.1 3.3 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EXF84389.1 - 0.0002 21.3 0.0 0.00045 20.1 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF84389.1 - 0.087 11.7 0.0 0.4 9.5 0.0 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EXF84389.1 - 0.15 10.4 0.1 0.27 9.6 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein p450 PF00067.17 EXF84390.1 - 2.5e-78 263.6 0.0 2.9e-78 263.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Flavokinase PF01687.12 EXF84391.1 - 6.5e-13 48.6 0.0 1.1e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase MFS_1 PF07690.11 EXF84393.1 - 5.4e-28 97.7 44.6 5.4e-28 97.7 30.9 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily FAD_binding_3 PF01494.14 EXF84394.1 - 2.3e-19 69.6 0.0 3.6e-09 36.1 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EXF84394.1 - 5.2e-06 25.5 1.1 8.7e-05 21.5 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EXF84394.1 - 6.5e-05 22.7 0.0 0.00016 21.4 0.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EXF84394.1 - 0.0033 17.3 0.4 0.012 15.6 0.3 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EXF84394.1 - 0.0083 14.7 0.4 1.8 7.0 0.2 2.3 2 0 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.22 EXF84394.1 - 0.053 13.9 1.5 0.51 10.7 0.2 3.0 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF84394.1 - 0.057 12.5 0.1 0.097 11.7 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.19 EXF84394.1 - 0.32 10.0 1.6 0.54 9.2 0.0 2.1 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase adh_short PF00106.20 EXF84396.1 - 1.3e-07 31.6 0.0 3.1e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EXF84396.1 - 0.02 14.9 0.0 0.042 13.8 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding ApbA PF02558.11 EXF84396.1 - 0.021 14.2 0.0 0.06 12.7 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA KR PF08659.5 EXF84396.1 - 0.023 14.3 0.0 0.042 13.5 0.0 1.4 1 0 0 1 1 1 0 KR domain Saccharop_dh PF03435.13 EXF84396.1 - 0.056 12.4 0.0 0.081 11.8 0.0 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Anoctamin PF04547.7 EXF84397.1 - 1.2e-106 357.1 1.9 1.4e-106 356.8 1.3 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel DUF4395 PF14340.1 EXF84397.1 - 0.044 13.8 0.3 0.044 13.8 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) AP_endonuc_2 PF01261.19 EXF84398.1 - 1.1e-29 103.3 0.0 1.4e-29 102.9 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF925 PF06042.6 EXF84399.1 - 4.5e-45 153.1 0.0 5.8e-45 152.7 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF925) VGCC_beta4Aa_N PF12052.3 EXF84399.1 - 0.13 12.1 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Ank_2 PF12796.2 EXF84400.1 - 4.8e-56 187.0 6.9 2e-18 66.5 0.1 3.6 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EXF84400.1 - 1.8e-37 125.2 11.0 7e-09 35.0 0.0 6.6 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EXF84400.1 - 3.9e-25 87.3 0.2 7.9e-07 29.1 0.0 5.9 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF84400.1 - 7.7e-22 75.2 3.2 8.5e-06 25.5 0.0 7.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 EXF84400.1 - 1.8e-21 76.0 5.5 1.2e-07 32.0 0.0 5.8 1 1 5 6 6 6 5 Ankyrin repeats (many copies) PNP_UDP_1 PF01048.15 EXF84400.1 - 2.3e-08 33.3 0.4 1e-07 31.2 0.3 2.0 1 1 0 1 1 1 1 Phosphorylase superfamily RVP PF00077.15 EXF84400.1 - 0.012 15.4 0.2 11 6.0 0.0 4.1 4 1 1 5 5 5 0 Retroviral aspartyl protease AAA_22 PF13401.1 EXF84400.1 - 0.028 14.5 0.1 1 9.5 0.0 2.8 2 0 0 2 2 2 0 AAA domain gag-asp_proteas PF13975.1 EXF84400.1 - 0.06 13.1 0.2 1.7 8.5 0.0 2.8 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease TauD PF02668.11 EXF84402.1 - 1.6e-48 165.6 0.7 1.9e-48 165.3 0.5 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family MFS_1 PF07690.11 EXF84403.1 - 1.4e-28 99.6 16.4 1.4e-28 99.6 11.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EXF84403.1 - 6.4e-07 29.0 0.1 1.8e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 MFS_1 like family Fungal_trans_2 PF11951.3 EXF84404.1 - 5.9e-06 25.1 0.0 1.4e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain Vhr1 PF04001.8 EXF84404.1 - 0.16 11.9 0.1 0.38 10.7 0.0 1.6 1 0 0 1 1 1 0 Transcription factor Vhr1 GFO_IDH_MocA PF01408.17 EXF84405.1 - 4.5e-23 82.0 0.2 7.6e-23 81.2 0.1 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EXF84405.1 - 5.1e-07 29.4 0.0 1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain Fungal_trans_2 PF11951.3 EXF84406.1 - 6.7e-05 21.6 0.0 9.7e-05 21.1 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Fungal_trans PF04082.13 EXF84406.1 - 0.0028 16.5 0.0 0.0043 15.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain GMC_oxred_N PF00732.14 EXF84407.1 - 3.3e-32 111.8 0.0 2.4e-22 79.4 0.0 3.2 3 0 0 3 3 3 3 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF84407.1 - 1e-29 103.6 0.1 1.7e-29 103.0 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EXF84407.1 - 0.00011 21.2 0.1 0.0018 17.1 0.1 2.2 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EXF84407.1 - 0.00016 21.5 0.2 0.00062 19.7 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF84407.1 - 0.0053 15.7 0.9 0.47 9.2 0.4 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF84407.1 - 0.011 15.6 0.0 0.14 12.0 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF84407.1 - 0.026 13.4 0.0 0.12 11.2 0.0 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EXF84407.1 - 0.049 13.6 0.1 6.9 6.6 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EXF84407.1 - 0.054 12.9 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_3 PF00933.16 EXF84408.1 - 1.5e-83 280.2 0.0 2.2e-83 279.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF84408.1 - 2.6e-51 174.3 0.3 2.5e-50 171.1 0.0 2.3 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF84408.1 - 6.9e-26 89.9 0.1 1.3e-25 89.0 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain HTH_12 PF08461.5 EXF84409.1 - 0.16 11.6 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain Chorion_S16 PF05836.7 EXF84410.1 - 0.083 12.7 0.3 0.12 12.2 0.2 1.2 1 0 0 1 1 1 0 Chorion protein S16 APG17 PF04108.7 EXF84411.1 - 7.2e-102 341.2 0.1 8.7e-102 340.9 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 SF-assemblin PF06705.6 EXF84411.1 - 0.0017 17.5 3.1 0.0024 17.0 0.2 2.6 3 1 1 4 4 4 1 SF-assemblin/beta giardin BLOC1_2 PF10046.4 EXF84411.1 - 1.9 8.6 5.6 37 4.5 0.0 3.4 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Choline_transpo PF04515.7 EXF84412.1 - 7.4e-106 353.6 23.0 7.4e-106 353.6 16.0 2.4 1 1 1 2 2 2 1 Plasma-membrane choline transporter Pex14_N PF04695.8 EXF84412.1 - 0.022 14.8 1.3 0.073 13.1 0.9 1.9 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ank_2 PF12796.2 EXF84415.1 - 6.5e-34 116.1 0.0 2.6e-13 50.1 0.0 5.6 5 2 1 6 6 6 4 Ankyrin repeats (3 copies) Ank PF00023.25 EXF84415.1 - 2e-26 90.4 5.7 0.00017 21.2 0.1 9.7 10 0 0 10 10 10 6 Ankyrin repeat Ank_3 PF13606.1 EXF84415.1 - 5.3e-23 78.8 9.0 6.9e-05 22.7 0.1 9.8 10 0 0 10 10 10 5 Ankyrin repeat Ank_4 PF13637.1 EXF84415.1 - 1.8e-18 66.5 3.1 0.00047 20.6 0.1 7.6 4 3 3 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF84415.1 - 9.7e-16 57.4 8.0 0.038 14.2 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeats (many copies) Sulfotransfer_3 PF13469.1 EXF84417.1 - 0.038 14.9 4.4 0.11 13.4 3.1 1.8 1 1 0 1 1 1 0 Sulfotransferase family WSC PF01822.14 EXF84419.1 - 0.14 12.1 1.6 0.27 11.1 1.1 1.5 1 0 0 1 1 1 0 WSC domain RIO1 PF01163.17 EXF84420.1 - 7.7e-70 234.1 0.1 1.8e-69 232.9 0.0 1.7 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EXF84420.1 - 3.5e-05 23.6 0.1 0.016 14.9 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EXF84420.1 - 0.00083 18.4 0.0 0.27 10.2 0.0 2.6 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Tyrosinase PF00264.15 EXF84421.1 - 3.5e-41 141.8 0.0 5.6e-41 141.1 0.0 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Glyco_tranf_2_2 PF10111.4 EXF84422.1 - 0.14 11.2 0.0 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase like family 2 F-box-like PF12937.2 EXF84423.1 - 0.0038 16.9 0.0 0.009 15.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EXF84423.1 - 0.024 14.2 0.0 0.057 13.0 0.0 1.7 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 EXF84424.1 - 0.00061 19.4 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EXF84424.1 - 0.033 13.8 0.2 0.15 11.7 0.0 2.2 2 0 0 2 2 2 0 F-box domain Peptidase_M14 PF00246.19 EXF84425.1 - 7.3e-71 239.0 0.1 8.7e-71 238.7 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase K_channel_TID PF07941.6 EXF84425.1 - 0.75 10.0 3.9 0.41 10.8 0.1 2.3 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain HNH_2 PF13391.1 EXF84426.1 - 0.054 13.2 0.0 0.18 11.5 0.0 2.0 1 1 0 1 1 1 0 HNH endonuclease Dynamin_N PF00350.18 EXF84427.1 - 1.5e-16 60.6 0.0 6.2e-16 58.6 0.0 2.1 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.18 EXF84427.1 - 0.002 18.0 0.1 0.043 13.7 0.0 2.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EXF84427.1 - 0.0024 17.0 0.0 0.021 13.9 0.0 2.3 2 0 0 2 2 2 1 AIG1 family GTP_EFTU PF00009.22 EXF84427.1 - 0.0031 16.9 0.0 0.72 9.2 0.0 2.6 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain ABC_tran PF00005.22 EXF84427.1 - 0.021 15.1 0.0 0.13 12.5 0.0 2.4 2 0 0 2 2 2 0 ABC transporter IIGP PF05049.8 EXF84427.1 - 0.036 12.8 0.7 0.19 10.4 0.0 2.4 3 0 0 3 3 3 0 Interferon-inducible GTPase (IIGP) DUF258 PF03193.11 EXF84427.1 - 0.047 12.8 0.0 0.19 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EXF84427.1 - 0.059 13.3 3.3 0.12 12.3 0.1 3.1 3 1 0 3 3 3 0 AAA ATPase domain DUF87 PF01935.12 EXF84427.1 - 0.12 12.1 2.3 0.3 10.8 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function DUF87 Amidohydro_3 PF07969.6 EXF84428.1 - 2.5e-54 185.0 3.9 3e-54 184.7 2.7 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EXF84428.1 - 5.6e-10 38.9 0.1 2.4e-09 36.8 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_4 PF13147.1 EXF84428.1 - 3.9e-07 30.4 6.4 0.0012 18.9 0.0 3.3 2 1 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EXF84428.1 - 1.5e-06 28.1 0.1 0.039 13.6 0.1 2.9 2 1 0 2 2 2 2 Amidohydrolase family Cutinase PF01083.17 EXF84429.1 - 5.8e-39 133.6 0.9 7.5e-39 133.3 0.6 1.1 1 0 0 1 1 1 1 Cutinase PE-PPE PF08237.6 EXF84429.1 - 0.0028 17.1 0.0 0.0042 16.5 0.0 1.2 1 0 0 1 1 1 1 PE-PPE domain Abhydrolase_5 PF12695.2 EXF84429.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EXF84429.1 - 0.021 14.2 0.0 0.033 13.6 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase MFS_1 PF07690.11 EXF84430.1 - 2.8e-33 115.0 31.9 2.8e-33 115.0 22.1 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily Pox_A14 PF05767.7 EXF84430.1 - 0.061 13.2 1.1 5.4 7.0 0.1 3.1 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 IncA PF04156.9 EXF84430.1 - 0.19 11.3 0.0 0.19 11.3 0.0 2.6 4 0 0 4 4 4 0 IncA protein GFO_IDH_MocA_C PF02894.12 EXF84431.1 - 2.2e-17 62.9 0.3 1e-16 60.7 0.2 2.2 2 0 0 2 2 2 1 Oxidoreductase family, C-terminal alpha/beta domain GFO_IDH_MocA PF01408.17 EXF84431.1 - 7.6e-16 58.7 0.0 1.4e-15 57.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Methyltransf_2 PF00891.13 EXF84432.1 - 2.5e-31 108.7 0.0 4.2e-31 107.9 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase MarR_2 PF12802.2 EXF84432.1 - 0.055 13.1 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 MarR family SH PF01445.12 EXF84433.1 - 0.17 11.5 2.0 0.22 11.2 0.0 2.2 2 0 0 2 2 2 0 Viral small hydrophobic protein Trehalase PF01204.13 EXF84434.1 - 2.5e-09 36.3 0.0 3.9e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Trehalase Glyco_hydro_63 PF03200.11 EXF84434.1 - 6.6e-05 20.9 5.8 0.046 11.5 0.1 3.7 2 1 0 3 3 3 2 Mannosyl oligosaccharide glucosidase DUF608 PF04685.8 EXF84434.1 - 0.03 13.0 0.0 0.048 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF608 Fungal_trans PF04082.13 EXF84435.1 - 0.0067 15.3 5.6 0.0088 14.9 0.2 2.4 2 0 0 2 2 2 2 Fungal specific transcription factor domain Glyco_hydro_39 PF01229.12 EXF84436.1 - 0.0012 17.3 0.5 0.0019 16.6 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Sugar_tr PF00083.19 EXF84437.1 - 5.3e-61 206.5 20.3 5.3e-61 206.5 14.0 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF84437.1 - 1.4e-16 60.1 27.8 1.8e-16 59.7 18.4 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1680 PF07944.7 EXF84438.1 - 2.7e-114 382.3 0.2 3.2e-114 382.0 0.1 1.0 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Prenyltrans_1 PF13243.1 EXF84438.1 - 0.0028 17.6 0.0 0.006 16.5 0.0 1.6 1 0 0 1 1 1 1 Prenyltransferase-like Prenyltrans_2 PF13249.1 EXF84438.1 - 0.061 13.7 0.1 0.32 11.4 0.0 2.2 2 0 0 2 2 2 0 Prenyltransferase-like Glyco_hydro_61 PF03443.9 EXF84439.1 - 1.8e-40 139.0 0.9 2.4e-40 138.6 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 HATPase_c_3 PF13589.1 EXF84440.1 - 2.6e-06 27.1 0.0 6.6e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HET PF06985.6 EXF84441.1 - 8.7e-23 81.0 0.0 1.7e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 EXF84442.1 - 2e-33 115.5 27.6 2e-33 115.5 19.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily FixQ PF05545.6 EXF84442.1 - 0.019 14.5 0.5 0.11 12.1 0.3 2.4 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ XhlA PF10779.4 EXF84442.1 - 0.079 12.8 0.8 1.7 8.5 0.3 2.6 2 0 0 2 2 2 0 Haemolysin XhlA DUF486 PF04342.7 EXF84442.1 - 0.13 12.2 6.2 0.23 11.5 0.5 3.0 2 1 0 2 2 2 0 Protein of unknown function, DUF486 DUF3328 PF11807.3 EXF84443.1 - 7.4e-47 159.8 1.1 9.2e-47 159.5 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Melibiase PF02065.13 EXF84444.1 - 6.2e-37 127.2 0.0 1.1e-36 126.4 0.0 1.3 1 0 0 1 1 1 1 Melibiase Glyco_hydro_31 PF01055.21 EXF84444.1 - 3.8e-06 26.0 0.1 5.5e-06 25.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Glyco_hydro_42M PF08532.5 EXF84446.1 - 0.0048 16.0 0.0 0.0097 15.0 0.0 1.4 1 0 0 1 1 1 1 Beta-galactosidase trimerisation domain NAD_binding_10 PF13460.1 EXF84447.1 - 3.4e-22 79.3 0.0 5.1e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EXF84447.1 - 2e-06 27.2 0.0 0.0058 15.9 0.0 2.1 2 0 0 2 2 2 2 NmrA-like family Epimerase PF01370.16 EXF84447.1 - 0.06 12.7 0.0 2.6 7.4 0.0 2.3 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EXF84447.1 - 0.095 11.5 0.0 0.23 10.2 0.0 1.6 2 0 0 2 2 2 0 RmlD substrate binding domain Herpes_gp2 PF05955.6 EXF84447.1 - 0.12 11.7 0.0 0.34 10.1 0.0 1.7 2 0 0 2 2 2 0 Equine herpesvirus glycoprotein gp2 RibD_C PF01872.12 EXF84448.1 - 7.1e-19 68.2 0.0 1.3e-18 67.3 0.0 1.4 1 1 0 1 1 1 1 RibD C-terminal domain DHFR_1 PF00186.14 EXF84448.1 - 1.8e-07 30.8 0.0 2.3e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Dihydrofolate reductase NmrA PF05368.8 EXF84449.1 - 1e-18 67.4 0.0 1.6e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF84449.1 - 2.1e-10 40.9 0.1 2.9e-10 40.4 0.1 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF84449.1 - 0.00049 19.5 0.0 0.00081 18.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EXF84449.1 - 0.011 14.5 0.1 0.087 11.5 0.0 2.1 2 0 0 2 2 2 0 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EXF84449.1 - 0.039 12.9 0.0 0.054 12.4 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase Mannitol_dh PF01232.18 EXF84449.1 - 0.083 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Mannitol dehydrogenase Rossmann domain Neur_chan_memb PF02932.11 EXF84450.1 - 0.0019 18.1 2.2 0.0023 17.8 1.5 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF3530 PF12048.3 EXF84450.1 - 0.12 11.3 8.9 0.0096 14.9 2.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3530) Gastrin PF00918.12 EXF84450.1 - 0.27 12.0 4.6 0.1 13.3 0.7 2.0 1 1 1 2 2 2 0 Gastrin/cholecystokinin family Presenilin PF01080.12 EXF84450.1 - 0.57 8.9 3.0 0.75 8.5 2.1 1.1 1 0 0 1 1 1 0 Presenilin Methyltransf_23 PF13489.1 EXF84451.1 - 3e-17 62.7 0.0 4.8e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF84451.1 - 8.4e-07 29.5 0.0 9.3e-06 26.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF84451.1 - 9.9e-07 28.4 0.0 1e-05 25.1 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF84451.1 - 1.6e-05 25.3 0.0 3.7e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF84451.1 - 2.4e-05 24.7 0.0 0.00032 21.0 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF84451.1 - 0.00077 19.7 0.0 0.002 18.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF84451.1 - 0.022 13.7 0.0 0.053 12.5 0.0 1.7 1 0 0 1 1 1 0 Putative methyltransferase MTS PF05175.9 EXF84451.1 - 0.1 11.9 0.0 0.22 10.8 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain Cutinase PF01083.17 EXF84454.1 - 3.3e-48 163.7 2.7 4.2e-48 163.4 1.9 1.1 1 0 0 1 1 1 1 Cutinase Thioesterase PF00975.15 EXF84454.1 - 0.0013 19.0 0.1 0.0021 18.3 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain Lipase_3 PF01764.20 EXF84454.1 - 0.0022 17.5 0.1 0.0029 17.2 0.1 1.3 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EXF84454.1 - 0.0023 17.6 0.3 0.0029 17.3 0.2 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EXF84454.1 - 0.0049 16.2 0.1 0.0077 15.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) PE-PPE PF08237.6 EXF84454.1 - 0.0055 16.1 0.2 0.0088 15.4 0.1 1.3 1 0 0 1 1 1 1 PE-PPE domain Chlorophyllase2 PF12740.2 EXF84454.1 - 0.0096 14.8 0.2 0.014 14.2 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_3 PF07859.8 EXF84454.1 - 0.031 13.8 0.5 0.053 13.0 0.3 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_1 PF00561.15 EXF84454.1 - 0.038 13.5 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold VirJ PF06057.6 EXF84454.1 - 0.13 12.0 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) Asp PF00026.18 EXF84455.1 - 7.6e-05 22.1 0.1 0.02 14.1 0.0 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease DUF4448 PF14610.1 EXF84455.1 - 0.09 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) VSP PF03302.8 EXF84455.1 - 0.37 9.3 1.5 0.61 8.6 1.0 1.2 1 0 0 1 1 1 0 Giardia variant-specific surface protein Formyl_trans_N PF00551.14 EXF84456.1 - 3.8e-35 121.0 0.1 5.3e-35 120.5 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.20 EXF84456.1 - 5.1e-08 32.2 0.0 1.3e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 ACT domain ACT_6 PF13740.1 EXF84456.1 - 0.033 13.9 0.1 0.13 11.9 0.0 2.2 2 1 0 2 2 2 0 ACT domain HET PF06985.6 EXF84457.1 - 1.6e-12 47.8 3.6 2.7e-12 47.0 0.1 2.6 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) zf-C2H2_4 PF13894.1 EXF84457.1 - 0.84 10.1 7.6 0.06 13.7 1.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_4 PF13894.1 EXF84460.1 - 0.013 15.7 7.0 1.1 9.7 0.1 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger PPP4R2 PF09184.6 EXF84460.1 - 0.71 9.3 6.4 1.5 8.3 4.4 1.4 1 0 0 1 1 1 0 PPP4R2 EBP PF05241.7 EXF84461.1 - 0.0029 16.6 2.1 0.0044 16.0 1.4 1.4 1 1 0 1 1 1 1 Emopamil binding protein CedA PF10729.4 EXF84462.1 - 0.051 13.1 0.0 1.2 8.7 0.0 2.5 2 0 0 2 2 2 0 Cell division activator CedA Dynactin_p62 PF05502.8 EXF84464.1 - 5.5e-162 539.8 0.1 6.6e-162 539.6 0.0 1.1 1 0 0 1 1 1 1 Dynactin p62 family DUF4519 PF15012.1 EXF84464.1 - 0.044 13.7 0.9 0.12 12.3 0.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Ribosomal_S7e PF01251.13 EXF84465.1 - 2.3e-83 278.3 0.2 2.5e-83 278.2 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e DUF4448 PF14610.1 EXF84466.1 - 2e-23 82.8 0.1 5.3e-16 58.6 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF4448) Pro_CA PF00484.14 EXF84467.1 - 2.1e-49 167.4 0.0 2.8e-49 167.0 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase SopA PF13981.1 EXF84467.1 - 0.099 12.6 0.1 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 SopA-like central domain FR47 PF08445.5 EXF84468.1 - 3e-05 23.6 0.0 5.5e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.19 EXF84468.1 - 0.00013 21.9 0.0 0.00021 21.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EXF84468.1 - 0.001 19.1 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EXF84468.1 - 0.012 15.7 0.0 0.018 15.1 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain COesterase PF00135.23 EXF84470.1 - 1.5e-83 281.3 0.4 1.8e-83 281.0 0.3 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF84470.1 - 3.5e-07 30.0 1.6 9.6e-07 28.5 0.2 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EXF84470.1 - 0.00044 19.5 0.5 0.0067 15.6 0.0 2.4 3 0 0 3 3 3 1 Prolyl oligopeptidase family bZIP_1 PF00170.16 EXF84471.1 - 0.001 18.9 7.6 0.001 18.9 5.2 2.1 2 0 0 2 2 2 1 bZIP transcription factor IL2 PF00715.12 EXF84471.1 - 0.18 11.5 0.0 0.37 10.4 0.0 1.4 1 0 0 1 1 1 0 Interleukin 2 bZIP_2 PF07716.10 EXF84471.1 - 4 7.3 15.4 0.037 13.8 4.9 2.0 2 0 0 2 2 2 0 Basic region leucine zipper HAD_2 PF13419.1 EXF84472.1 - 4.9e-28 98.5 0.0 4.4e-27 95.4 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EXF84472.1 - 6.7e-05 22.5 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Prenyltrans_2 PF13249.1 EXF84472.1 - 0.00076 19.8 0.0 0.089 13.1 0.0 2.9 2 1 0 2 2 2 1 Prenyltransferase-like Hydrolase PF00702.21 EXF84472.1 - 0.0086 16.5 0.0 0.017 15.5 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Prenyltrans_1 PF13243.1 EXF84472.1 - 0.11 12.5 0.0 0.51 10.3 0.0 2.1 2 0 0 2 2 2 0 Prenyltransferase-like DUF2608 PF11019.3 EXF84472.1 - 0.12 11.3 0.6 0.28 10.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2608) DUF1056 PF06341.6 EXF84473.1 - 2.2 8.3 6.0 0.34 10.9 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1056) Methyltransf_23 PF13489.1 EXF84474.1 - 9.9e-17 61.1 0.0 1.5e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF84474.1 - 4.9e-10 39.1 0.0 8e-09 35.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF84474.1 - 5e-08 33.3 0.0 4.9e-07 30.1 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF84474.1 - 7.3e-08 32.9 0.0 1.3e-06 28.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF84474.1 - 5e-07 30.1 0.0 9e-06 26.0 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF84474.1 - 9.3e-06 25.9 0.0 2.7e-05 24.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EXF84474.1 - 0.00056 19.1 0.0 0.00092 18.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EXF84474.1 - 0.00065 18.8 0.0 0.023 13.8 0.0 2.1 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EXF84474.1 - 0.0014 17.7 0.0 0.0031 16.6 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase FtsJ PF01728.14 EXF84474.1 - 0.0053 16.7 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase MTS PF05175.9 EXF84474.1 - 0.0057 16.0 0.0 0.0096 15.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EXF84474.1 - 0.013 15.5 0.0 0.036 14.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EXF84474.1 - 0.014 14.8 0.0 0.037 13.4 0.0 1.5 1 1 0 1 1 1 0 Putative methyltransferase PCMT PF01135.14 EXF84474.1 - 0.052 13.0 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Vwaint PF14624.1 EXF84474.1 - 0.057 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 VWA / Hh protein intein-like CMAS PF02353.15 EXF84474.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.6 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EXF84475.1 - 4.1e-19 68.8 0.0 6.4e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF84475.1 - 2.8e-10 39.9 0.0 3.8e-09 36.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF84475.1 - 2.3e-09 37.8 0.0 3.1e-08 34.1 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF84475.1 - 1.1e-07 32.2 0.0 2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF84475.1 - 1.9e-06 28.2 0.0 1.4e-05 25.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF84475.1 - 0.00053 20.3 0.0 0.0015 18.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF84475.1 - 0.0025 17.2 0.0 0.005 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EXF84475.1 - 0.004 16.2 0.0 0.0079 15.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.8 EXF84475.1 - 0.0044 16.1 0.0 0.007 15.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EXF84475.1 - 0.0091 15.1 0.0 0.031 13.3 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EXF84475.1 - 0.02 14.8 0.0 0.075 13.0 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain DUF938 PF06080.7 EXF84475.1 - 0.084 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF938) FtsJ PF01728.14 EXF84475.1 - 0.092 12.7 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EXF84475.1 - 0.099 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase FAD_binding_4 PF01565.18 EXF84477.1 - 2.8e-24 85.1 4.5 4.6e-24 84.4 3.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF84477.1 - 1.4e-05 24.9 0.0 2.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like DUF3733 PF12534.3 EXF84478.1 - 0.099 11.9 1.9 0.16 11.2 0.1 2.2 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 Methyltransf_23 PF13489.1 EXF84479.1 - 9.3e-22 77.4 0.0 1.3e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF84479.1 - 4.7e-09 35.9 0.0 4.2e-08 32.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF84479.1 - 5.4e-09 36.4 0.0 9.1e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF84479.1 - 4.3e-08 33.7 0.1 5.3e-07 30.2 0.1 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF84479.1 - 7e-08 32.8 0.0 8.8e-07 29.3 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF84479.1 - 1.3e-06 28.6 0.0 3.2e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EXF84479.1 - 0.00017 20.8 0.0 0.00031 19.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EXF84479.1 - 0.0073 15.6 0.0 0.013 14.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.14 EXF84479.1 - 0.012 15.5 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase GidB PF02527.10 EXF84479.1 - 0.026 13.6 0.0 0.13 11.3 0.0 1.9 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G PCMT PF01135.14 EXF84479.1 - 0.031 13.7 0.0 0.075 12.5 0.0 1.6 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.13 EXF84479.1 - 0.047 12.8 0.0 0.24 10.4 0.0 2.0 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EXF84479.1 - 0.092 11.8 0.0 0.13 11.3 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Glyco_transf_25 PF01755.12 EXF84480.1 - 9e-16 58.1 0.0 3.8e-11 43.0 0.0 2.1 2 0 0 2 2 2 2 Glycosyltransferase family 25 (LPS biosynthesis protein) PALP PF00291.20 EXF84481.1 - 9.8e-72 241.7 6.8 1.1e-71 241.5 4.7 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Glyco_tran_WecB PF03808.8 EXF84481.1 - 0.011 15.0 0.6 0.051 12.9 0.0 2.2 2 1 1 3 3 3 0 Glycosyl transferase WecB/TagA/CpsF family Pex14_N PF04695.8 EXF84482.1 - 0.0055 16.7 5.4 0.014 15.4 3.8 1.7 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region SOBP PF15279.1 EXF84482.1 - 0.011 16.2 2.9 0.017 15.4 2.0 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein PAP1 PF08601.5 EXF84482.1 - 0.12 12.0 13.6 0.18 11.4 9.4 1.3 1 0 0 1 1 1 0 Transcription factor PAP1 DUF566 PF04484.7 EXF84482.1 - 0.16 11.4 13.5 0.27 10.7 9.4 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF566) Macoilin PF09726.4 EXF84482.1 - 2.1 6.4 16.1 2.9 6.0 11.2 1.1 1 0 0 1 1 1 0 Transmembrane protein DNA_pol_viral_N PF00242.12 EXF84482.1 - 4.1 6.3 14.9 5.7 5.8 10.4 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DUF572 PF04502.8 EXF84482.1 - 7.7 5.6 6.6 11 5.0 4.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) RTA1 PF04479.8 EXF84483.1 - 1e-26 93.8 7.0 1.3e-26 93.4 4.9 1.1 1 0 0 1 1 1 1 RTA1 like protein DDRGK PF09756.4 EXF84483.1 - 0.24 10.7 7.7 0.32 10.3 5.3 1.1 1 0 0 1 1 1 0 DDRGK domain Ion_trans PF00520.26 EXF84484.1 - 8.3e-07 28.4 26.2 2e-06 27.1 14.7 3.1 2 1 0 2 2 2 1 Ion transport protein Abhydrolase_2 PF02230.11 EXF84485.1 - 1.3e-56 191.4 0.0 8.4e-35 120.1 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EXF84485.1 - 4.2e-10 39.5 0.1 1.3e-09 37.9 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF84485.1 - 7.3e-07 29.3 4.8 0.00085 19.2 1.4 3.0 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF84485.1 - 0.00019 20.7 0.1 0.0079 15.4 0.0 2.9 4 0 0 4 4 4 1 Prolyl oligopeptidase family FSH1 PF03959.8 EXF84485.1 - 0.017 14.5 0.0 0.14 11.6 0.0 2.2 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.8 EXF84485.1 - 0.081 12.4 1.0 0.4 10.2 0.1 2.4 2 1 1 3 3 3 0 alpha/beta hydrolase fold Cutinase PF01083.17 EXF84485.1 - 0.092 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Cutinase Lipase_3 PF01764.20 EXF84485.1 - 0.1 12.1 0.0 0.31 10.6 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) DUF2974 PF11187.3 EXF84485.1 - 0.16 11.3 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) IMD PF08397.6 EXF84486.1 - 0.0026 17.1 2.0 0.0043 16.4 0.1 1.9 2 0 0 2 2 2 1 IRSp53/MIM homology domain Rabaptin PF03528.10 EXF84486.1 - 0.056 13.3 0.5 0.12 12.2 0.3 1.6 1 0 0 1 1 1 0 Rabaptin Rad21_Rec8_N PF04825.8 EXF84488.1 - 2.8e-28 98.0 0.0 4.3e-28 97.4 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EXF84488.1 - 1.9e-06 26.9 0.0 4.3e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein ScpA_ScpB PF02616.9 EXF84488.1 - 0.02 14.5 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 ScpA/B protein GDI PF00996.13 EXF84489.1 - 4.9e-40 137.1 0.0 6.7e-40 136.7 0.0 1.2 1 0 0 1 1 1 1 GDP dissociation inhibitor RNase_PH PF01138.16 EXF84491.1 - 2.4e-16 60.2 0.0 6.9e-16 58.7 0.0 1.8 1 1 0 1 1 1 1 3' exoribonuclease family, domain 1 Nucleoplasmin PF03066.10 EXF84491.1 - 0.05 13.1 0.2 0.076 12.5 0.2 1.3 1 0 0 1 1 1 0 Nucleoplasmin p450 PF00067.17 EXF84492.1 - 4.9e-13 48.4 0.0 6.6e-13 47.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF998 PF06197.8 EXF84492.1 - 0.0033 16.7 0.1 0.0056 16.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF998) Solute_trans_a PF03619.11 EXF84493.1 - 2.5e-49 168.0 10.2 3e-49 167.7 7.1 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha API5 PF05918.6 EXF84493.1 - 0.22 9.9 0.2 0.3 9.5 0.1 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) L_HGMIC_fpl PF10242.4 EXF84493.1 - 7.7 6.4 9.0 2.7 7.9 1.6 2.2 1 1 1 2 2 2 0 Lipoma HMGIC fusion partner-like protein Pam16 PF03656.8 EXF84494.1 - 1.2e-33 115.6 0.1 1.4e-33 115.4 0.1 1.0 1 0 0 1 1 1 1 Pam16 Beta_helix PF13229.1 EXF84495.1 - 3.7e-10 39.7 20.8 1.7e-09 37.5 4.6 2.8 2 1 1 3 3 3 2 Right handed beta helix region Chondroitinas_B PF14592.1 EXF84495.1 - 1e-06 27.8 0.3 3.2e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 Chondroitinase B DUF1565 PF07602.6 EXF84495.1 - 0.00026 20.2 0.3 0.00026 20.2 0.2 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF1565) Yip1 PF04893.12 EXF84496.1 - 0.00018 21.0 16.6 0.0019 17.7 4.9 2.8 3 1 0 3 3 3 2 Yip1 domain RCC1 PF00415.13 EXF84497.1 - 1.4e-59 198.0 2.1 2.5e-10 40.3 0.0 8.0 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EXF84497.1 - 1.3e-34 117.0 31.1 3.9e-08 32.6 0.9 6.8 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat MIP-T3 PF10243.4 EXF84497.1 - 0.00043 18.8 43.8 0.00057 18.4 30.3 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 TFIIA PF03153.8 EXF84497.1 - 0.037 13.9 23.4 0.06 13.2 16.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Toxin_ToxA PF11584.3 EXF84497.1 - 0.14 11.9 0.0 0.33 10.7 0.0 1.6 1 0 0 1 1 1 0 Proteinaceous host-selective toxin ToxA APH PF01636.18 EXF84499.1 - 0.0099 15.6 0.0 0.025 14.3 0.0 1.7 2 1 0 2 2 2 1 Phosphotransferase enzyme family HBS1_N PF08938.5 EXF84499.1 - 0.011 15.8 0.0 0.12 12.4 0.0 2.4 2 0 0 2 2 2 0 HBS1 N-terminus Adeno_E4_34 PF04528.8 EXF84499.1 - 0.022 14.3 0.0 0.06 12.9 0.0 1.7 1 0 0 1 1 1 0 Adenovirus early E4 34 kDa protein conserved region Choline_kinase PF01633.15 EXF84499.1 - 0.06 12.9 0.0 0.09 12.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase GMC_oxred_N PF00732.14 EXF84500.1 - 9.3e-58 195.7 0.0 1.3e-57 195.2 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF84500.1 - 6.9e-24 84.7 2.7 1.3e-22 80.6 0.9 3.1 2 1 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EXF84500.1 - 5.9e-05 22.1 0.0 0.0036 16.2 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EXF84500.1 - 0.00016 21.7 0.0 0.8 9.7 0.0 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF84500.1 - 0.00016 20.6 0.0 0.048 12.5 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EXF84500.1 - 0.0026 17.7 0.0 0.0074 16.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF84500.1 - 0.013 15.3 0.0 0.84 9.4 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase EphA2_TM PF14575.1 EXF84500.1 - 0.014 15.7 0.1 0.04 14.3 0.1 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain HI0933_like PF03486.9 EXF84500.1 - 0.16 10.4 0.0 0.34 9.3 0.0 1.5 2 0 0 2 2 2 0 HI0933-like protein AA_permease_2 PF13520.1 EXF84501.1 - 4e-57 193.6 51.6 4.9e-57 193.3 35.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF84501.1 - 4.1e-30 104.5 41.0 5.7e-30 104.0 28.4 1.1 1 0 0 1 1 1 1 Amino acid permease TB2_DP1_HVA22 PF03134.14 EXF84502.1 - 5e-31 106.2 8.6 7.1e-31 105.8 5.9 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family ABC2_membrane_3 PF12698.2 EXF84502.1 - 0.98 8.3 4.2 1.3 7.9 2.9 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Mgm101p PF06420.7 EXF84503.1 - 3.1e-88 293.5 0.0 4.1e-88 293.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 Suf PF05843.9 EXF84503.1 - 0.011 15.5 6.6 0.015 15.0 4.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF605 PF04652.11 EXF84503.1 - 3.7 6.8 26.1 4.6 6.5 18.1 1.1 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 EXF84503.1 - 3.9 7.2 15.6 5.1 6.8 10.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EXF84503.1 - 5.9 4.9 16.9 7.1 4.7 11.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CHCH PF06747.8 EXF84504.1 - 0.0057 16.5 8.2 0.011 15.6 5.7 1.5 1 0 0 1 1 1 1 CHCH domain COX17 PF05051.8 EXF84504.1 - 0.014 15.4 2.0 0.021 14.8 1.4 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.5 EXF84504.1 - 0.036 13.8 4.3 0.1 12.3 3.0 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like BPL_N PF09825.4 EXF84505.1 - 6.5e-137 456.2 0.0 8.1e-137 455.9 0.0 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal BPL_LplA_LipB PF03099.14 EXF84505.1 - 6.7e-18 64.9 0.0 1.2e-17 64.0 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Asp PF00026.18 EXF84507.1 - 3.2e-74 250.0 15.3 3.9e-74 249.7 10.6 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EXF84507.1 - 1.3e-08 34.9 3.2 2.8e-08 33.9 0.4 2.7 1 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EXF84507.1 - 1.8e-05 25.1 2.2 0.0036 17.7 0.3 2.7 2 0 0 2 2 2 2 Aspartyl protease BNR_2 PF13088.1 EXF84508.1 - 0.0053 16.0 0.0 0.012 14.9 0.0 1.6 1 0 0 1 1 1 1 BNR repeat-like domain BNR PF02012.15 EXF84508.1 - 0.061 13.1 0.8 0.061 13.1 0.5 3.2 2 0 0 2 2 2 0 BNR/Asp-box repeat Sugar_tr PF00083.19 EXF84509.1 - 1.9e-117 392.6 22.8 2.2e-117 392.4 15.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF84509.1 - 7.1e-23 80.8 60.4 5e-21 74.8 19.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Fungal_trans PF04082.13 EXF84510.1 - 1.2e-14 53.8 0.0 1.9e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF84510.1 - 4e-08 33.0 6.7 7e-08 32.2 4.6 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain CGI-121 PF08617.5 EXF84511.1 - 3.6e-51 173.0 0.0 4.2e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 DUF2860 PF11059.3 EXF84511.1 - 0.079 11.9 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2860) Pro_dh PF01619.13 EXF84512.1 - 2.7e-38 131.7 0.0 3.8e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase Tim17 PF02466.14 EXF84513.1 - 0.0013 18.7 2.9 0.0024 17.9 2.0 1.5 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Metallophos PF00149.23 EXF84515.1 - 2e-09 37.1 4.1 8.9e-09 35.0 2.8 2.2 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase NIF PF03031.13 EXF84517.1 - 7.6e-37 126.4 0.0 1.1e-36 125.8 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase RNase_PH PF01138.16 EXF84518.1 - 1.7e-35 122.2 0.3 3.9e-35 121.0 0.1 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Thioredoxin PF00085.15 EXF84519.1 - 3.7e-34 116.5 0.1 8.3e-27 92.9 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_6 PF13848.1 EXF84519.1 - 2.4e-15 56.8 0.0 6.2e-05 22.8 0.0 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EXF84519.1 - 2.7e-06 27.5 5.7 0.0037 17.4 0.2 3.5 3 1 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EXF84519.1 - 4.8e-06 26.6 0.1 0.0053 16.8 0.0 4.0 3 2 1 4 4 4 1 Thioredoxin-like Thioredoxin_3 PF13192.1 EXF84519.1 - 0.0015 18.3 0.1 0.25 11.1 0.0 2.6 2 0 0 2 2 2 1 Thioredoxin domain ERp29_N PF07912.8 EXF84519.1 - 0.0099 15.8 0.0 0.77 9.7 0.0 2.4 1 1 1 2 2 2 1 ERp29, N-terminal domain Thioredoxin_7 PF13899.1 EXF84519.1 - 0.01 15.8 0.0 0.024 14.6 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like HyaE PF07449.6 EXF84519.1 - 0.062 13.2 0.0 4 7.3 0.0 3.2 2 1 0 2 2 2 0 Hydrogenase-1 expression protein HyaE NARP1 PF12569.3 EXF84519.1 - 0.24 10.1 1.6 0.35 9.5 1.1 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF4551 PF15087.1 EXF84519.1 - 0.35 9.1 4.1 0.59 8.4 2.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF2360 PF10152.4 EXF84519.1 - 0.52 10.5 7.4 2.2 8.5 0.9 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) CPSF100_C PF13299.1 EXF84519.1 - 0.84 9.8 5.6 9.5 6.3 1.6 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Di19_C PF14571.1 EXF84519.1 - 1 9.7 7.6 0.14 12.4 1.3 2.3 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal DUF605 PF04652.11 EXF84520.1 - 1.3e-91 307.8 19.0 1.5e-91 307.6 13.2 1.0 1 0 0 1 1 1 1 Vta1 like DUF445 PF04286.7 EXF84520.1 - 0.026 14.0 0.4 0.036 13.6 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) HEAT_EZ PF13513.1 EXF84520.1 - 0.055 13.9 0.5 3.5 8.2 0.0 2.8 2 0 0 2 2 2 0 HEAT-like repeat adh_short_C2 PF13561.1 EXF84521.1 - 1e-34 120.3 0.1 1.3e-34 119.9 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EXF84521.1 - 1.1e-24 87.2 0.0 1.4e-24 86.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF84521.1 - 1.4e-10 41.1 0.2 3.3e-10 39.9 0.2 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF84521.1 - 2.8e-07 30.2 0.1 4.6e-07 29.5 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EXF84521.1 - 8.9e-06 25.0 0.0 1.3e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.10 EXF84521.1 - 0.0021 17.0 0.2 0.0027 16.6 0.2 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EXF84521.1 - 0.0041 16.8 0.6 0.01 15.5 0.4 1.7 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EXF84521.1 - 0.0056 16.7 1.5 0.024 14.6 1.2 1.9 1 1 1 2 2 2 1 NADH(P)-binding DUF2493 PF10686.4 EXF84521.1 - 0.1 12.1 0.1 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2493) ADH_N PF08240.7 EXF84522.1 - 1e-26 92.8 2.4 1.8e-26 92.0 1.7 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF84522.1 - 2e-17 62.9 0.0 3e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF84522.1 - 0.018 15.9 0.0 0.034 15.0 0.0 1.4 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 EXF84522.1 - 0.024 14.1 0.3 0.038 13.5 0.2 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF1664 PF07889.7 EXF84523.1 - 0.17 11.7 12.7 0.099 12.4 1.6 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) FimP PF09766.4 EXF84523.1 - 1.1 8.2 16.1 0.11 11.5 2.5 2.2 2 0 0 2 2 2 0 Fms-interacting protein COG2 PF06148.6 EXF84523.1 - 8.7 6.2 12.5 3 7.7 0.8 3.5 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF1469 PF07332.6 EXF84524.1 - 5.2 6.8 7.3 0.58 9.8 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) Glyco_hydro_43 PF04616.9 EXF84525.1 - 6.2e-62 209.2 0.0 8.8e-62 208.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF3503 PF12011.3 EXF84525.1 - 0.00077 19.2 0.1 0.0013 18.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3503) FAD_binding_3 PF01494.14 EXF84526.1 - 7.3e-24 84.4 0.1 5.4e-14 51.9 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain Amino_oxidase PF01593.19 EXF84526.1 - 0.0025 16.9 0.1 1.2 8.1 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 EXF84526.1 - 0.0037 16.2 0.1 0.74 8.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EXF84526.1 - 0.005 15.5 0.1 0.4 9.2 0.0 2.7 2 1 1 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.22 EXF84526.1 - 0.0075 16.6 3.3 0.008 16.5 0.1 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF84526.1 - 0.018 14.8 0.1 0.38 10.6 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF84526.1 - 0.041 13.8 0.0 0.11 12.5 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EXF84526.1 - 0.043 12.7 0.2 5.8 5.7 0.0 2.6 3 0 0 3 3 3 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EXF84527.1 - 3.3e-42 144.8 0.0 4e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF84527.1 - 1.8e-05 23.8 0.0 3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EXF84527.1 - 7.2e-05 23.1 0.1 0.00086 19.6 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF84527.1 - 9.3e-05 21.0 0.2 0.00014 20.4 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_2 PF07992.9 EXF84527.1 - 0.0001 22.2 0.1 0.00019 21.3 0.1 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF84527.1 - 0.00011 21.2 0.0 0.00017 20.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EXF84527.1 - 0.00032 20.6 0.1 0.00078 19.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EXF84527.1 - 0.0011 19.0 0.0 0.0028 17.7 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF84527.1 - 0.0016 17.4 0.1 0.0032 16.4 0.0 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EXF84527.1 - 0.0051 15.9 0.1 0.012 14.7 0.1 1.5 1 0 0 1 1 1 1 Thi4 family ThiF PF00899.16 EXF84527.1 - 0.0078 16.0 0.2 0.022 14.5 0.1 1.8 1 0 0 1 1 1 1 ThiF family UDPG_MGDP_dh_N PF03721.9 EXF84527.1 - 0.027 13.8 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 EXF84527.1 - 0.029 13.8 0.1 0.048 13.0 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.2 EXF84527.1 - 0.046 12.8 0.0 0.096 11.7 0.0 1.5 1 1 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EXF84527.1 - 0.054 13.7 0.1 0.36 11.1 0.0 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.13 EXF84527.1 - 0.061 12.9 0.0 0.099 12.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.17 EXF84527.1 - 0.14 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A p450 PF00067.17 EXF84528.1 - 9e-45 153.0 0.0 1.4e-29 102.9 0.0 2.0 1 1 1 2 2 2 2 Cytochrome P450 p450 PF00067.17 EXF84529.1 - 2.2e-57 194.6 0.0 2.5e-57 194.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_32N PF00251.15 EXF84530.1 - 5.5e-76 255.8 3.3 6.8e-76 255.5 2.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.7 EXF84530.1 - 0.0051 17.1 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal Aldo_ket_red PF00248.16 EXF84531.1 - 3.7e-46 157.2 0.0 4.1e-46 157.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family UDPGT PF00201.13 EXF84532.1 - 1.1e-05 24.2 0.0 1.5e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase PsaM PF07465.8 EXF84532.1 - 0.49 10.0 5.7 1 9.0 4.0 1.5 1 0 0 1 1 1 0 Photosystem I protein M (PsaM) p450 PF00067.17 EXF84533.1 - 1.2e-66 225.1 0.0 1.5e-66 224.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Acyl_transf_1 PF00698.16 EXF84534.1 - 3.4e-28 98.8 0.5 4.4e-28 98.5 0.4 1.1 1 0 0 1 1 1 1 Acyl transferase domain DBD_Tnp_Mut PF03108.10 EXF84534.1 - 0.051 13.1 0.4 3.5 7.2 0.0 2.4 2 0 0 2 2 2 0 MuDR family transposase GBP_C PF02841.9 EXF84535.1 - 0.072 12.2 2.4 0.095 11.8 1.7 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Di19_C PF14571.1 EXF84535.1 - 0.097 12.9 0.4 0.16 12.2 0.3 1.4 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal Zn_clus PF00172.13 EXF84535.1 - 0.11 12.4 8.7 0.18 11.7 6.1 1.3 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain FAM178 PF14816.1 EXF84535.1 - 0.18 10.4 0.3 0.23 10.1 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function, FAM178 APH PF01636.18 EXF84535.1 - 0.26 10.9 6.4 2.5 7.7 4.4 2.0 1 1 0 1 1 1 0 Phosphotransferase enzyme family muHD PF10291.4 EXF84536.1 - 1e-70 237.8 0.0 1.5e-70 237.2 0.0 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain FCH PF00611.18 EXF84536.1 - 1.9e-10 40.7 0.8 8.3e-10 38.7 0.0 2.3 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain LON PF02190.11 EXF84536.1 - 0.099 12.2 0.4 0.2 11.2 0.3 1.5 1 0 0 1 1 1 0 ATP-dependent protease La (LON) domain DUF3584 PF12128.3 EXF84536.1 - 0.13 9.5 15.3 0.19 9.0 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF310 PF03750.8 EXF84536.1 - 0.14 12.3 1.5 0.85 9.8 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF310) Fib_alpha PF08702.5 EXF84536.1 - 5.3 7.1 8.0 6.5 6.8 2.9 2.6 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family MAD PF05557.8 EXF84537.1 - 2.1e-51 174.9 55.5 3.3e-51 174.2 38.5 1.2 1 0 0 1 1 1 1 Mitotic checkpoint protein Atg14 PF10186.4 EXF84537.1 - 0.0015 17.5 1.0 0.0015 17.5 0.7 5.1 3 2 2 5 5 5 2 UV radiation resistance protein and autophagy-related subunit 14 Mmp37 PF09139.6 EXF84538.1 - 1.8e-127 424.9 0.0 2.2e-127 424.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial matrix Mmp37 FMO-like PF00743.14 EXF84540.1 - 3.9e-35 121.0 0.0 2.6e-19 68.8 0.1 3.0 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EXF84540.1 - 1.5e-18 67.6 0.0 3.1e-18 66.5 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF84540.1 - 9.8e-12 44.9 0.0 4.3e-10 39.5 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EXF84540.1 - 5.8e-10 39.3 0.0 9.6e-09 35.3 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF84540.1 - 7.1e-08 31.7 0.0 9.5e-05 21.4 0.0 3.0 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EXF84540.1 - 1.9e-07 30.9 0.0 4.6e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EXF84540.1 - 3.5e-07 29.5 0.1 4.4e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.2 EXF84540.1 - 0.00046 19.3 0.0 0.00066 18.8 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EXF84540.1 - 0.0016 18.7 0.1 0.047 14.0 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF84540.1 - 0.0068 14.9 0.0 0.017 13.5 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein Amino_oxidase PF01593.19 EXF84540.1 - 0.013 14.5 0.0 0.036 13.1 0.0 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase NAD_Gly3P_dh_N PF01210.18 EXF84540.1 - 0.017 14.8 0.0 0.55 9.9 0.0 2.3 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus DAO PF01266.19 EXF84540.1 - 0.021 13.7 0.0 0.19 10.6 0.0 2.3 3 0 0 3 3 3 0 FAD dependent oxidoreductase Shikimate_DH PF01488.15 EXF84540.1 - 0.031 14.3 0.0 0.71 9.9 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase Semialdhyde_dh PF01118.19 EXF84540.1 - 0.044 14.0 0.0 5.3 7.3 0.0 3.6 3 2 1 4 4 4 0 Semialdehyde dehydrogenase, NAD binding domain DJ-1_PfpI PF01965.19 EXF84540.1 - 0.078 12.4 0.0 15 5.0 0.0 2.3 2 0 0 2 2 2 0 DJ-1/PfpI family FAD_binding_3 PF01494.14 EXF84540.1 - 0.1 11.6 0.0 0.28 10.1 0.0 1.7 2 0 0 2 2 2 0 FAD binding domain GST_N_2 PF13409.1 EXF84541.1 - 1.9e-20 72.6 0.0 3.5e-20 71.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EXF84541.1 - 1.9e-17 62.8 0.1 4.4e-17 61.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EXF84541.1 - 1.8e-10 40.6 0.0 3.6e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EXF84541.1 - 8.1e-07 29.4 0.0 2.5e-06 27.8 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EXF84541.1 - 3e-06 27.3 0.0 0.0067 16.6 0.0 2.3 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EXF84541.1 - 0.014 15.3 0.0 0.36 10.8 0.0 2.4 2 0 0 2 2 2 0 Glutaredoxin Peptidase_M20 PF01546.23 EXF84542.1 - 7.8e-10 38.5 0.5 1.4e-09 37.7 0.3 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EXF84542.1 - 6.3e-08 32.3 0.2 2.9e-07 30.1 0.1 2.1 1 1 0 1 1 1 1 Peptidase dimerisation domain Zn_clus PF00172.13 EXF84543.1 - 2.8e-05 23.9 13.5 5.8e-05 22.9 9.3 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Esterase_phd PF10503.4 EXF84545.1 - 7.9e-23 80.8 0.2 1e-22 80.4 0.1 1.1 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EXF84545.1 - 9.8e-08 31.4 0.1 1.4e-07 30.9 0.1 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EXF84545.1 - 2.1e-06 27.5 0.3 4.1e-06 26.6 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EXF84545.1 - 0.01 15.4 0.1 0.015 14.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Utp12 PF04003.7 EXF84546.1 - 4.2e-20 71.7 0.0 1.5e-19 69.8 0.0 2.0 2 0 0 2 2 2 1 Dip2/Utp12 Family BUD22 PF09073.5 EXF84546.1 - 1.2 8.0 37.0 0.034 13.2 14.4 2.2 2 0 0 2 2 2 0 BUD22 BSP_II PF05432.6 EXF84546.1 - 7.7 5.6 47.7 0.015 14.5 6.9 3.1 2 1 1 3 3 3 0 Bone sialoprotein II (BSP-II) Bromodomain PF00439.20 EXF84547.1 - 4e-34 116.3 0.3 1.1e-18 66.8 0.0 2.9 3 0 0 3 3 3 2 Bromodomain Pro_racemase PF05544.6 EXF84549.1 - 2.2e-56 191.0 3.1 6e-28 97.6 0.2 2.5 1 1 1 2 2 2 2 Proline racemase Abhydrolase_6 PF12697.2 EXF84550.1 - 2.9e-28 99.3 0.0 3.5e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF84550.1 - 9.3e-12 44.9 0.0 4.3e-11 42.8 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF84550.1 - 2.2e-08 34.0 0.0 2.8e-08 33.6 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EXF84550.1 - 0.018 14.9 0.0 0.046 13.5 0.0 1.8 1 0 0 1 1 1 0 Putative lysophospholipase EHN PF06441.7 EXF84550.1 - 0.045 13.6 0.3 0.084 12.8 0.2 1.4 1 0 0 1 1 1 0 Epoxide hydrolase N terminus AXE1 PF05448.7 EXF84550.1 - 0.049 12.1 0.0 0.069 11.6 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) UCR_Fe-S_N PF10399.4 EXF84553.1 - 0.67 9.1 4.6 4.4 6.5 3.6 2.1 2 0 0 2 2 2 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal gag-asp_proteas PF13975.1 EXF84554.1 - 1.9e-13 50.0 2.5 2.2e-08 33.7 0.0 3.1 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.1 EXF84554.1 - 1.8e-11 44.3 0.0 1.9e-07 31.5 0.0 3.0 3 0 0 3 3 3 2 Aspartyl protease DnaJ PF00226.26 EXF84554.1 - 2.8e-06 26.9 0.0 0.0054 16.4 0.0 3.3 3 0 0 3 3 3 2 DnaJ domain Asp_protease PF09668.5 EXF84554.1 - 0.11 12.0 0.0 0.8 9.2 0.0 2.3 3 0 0 3 3 3 0 Aspartyl protease DUF1741 PF08427.5 EXF84555.1 - 1.6e-83 279.8 0.0 2.6e-83 279.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) Fe-S_biosyn PF01521.15 EXF84556.1 - 9.1e-18 64.2 0.0 1.3e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Mucin PF01456.12 EXF84556.1 - 0.018 14.8 15.0 0.023 14.4 10.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein KAR9 PF08580.5 EXF84556.1 - 0.082 11.1 5.1 0.095 10.9 3.5 1.1 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Hamartin PF04388.7 EXF84556.1 - 0.56 8.8 5.6 0.59 8.7 3.9 1.2 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.8 EXF84556.1 - 0.56 10.0 7.5 0.65 9.8 5.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mcm10 PF09332.6 EXF84556.1 - 0.6 9.4 8.3 0.78 9.0 5.8 1.1 1 0 0 1 1 1 0 Mcm10 replication factor SSP160 PF06933.6 EXF84556.1 - 0.67 7.8 14.6 0.91 7.4 10.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CDC27 PF09507.5 EXF84556.1 - 0.73 8.9 13.4 0.89 8.7 9.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CAF-1_p150 PF11600.3 EXF84556.1 - 1.5 8.1 6.2 2.1 7.6 4.3 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal RAP1 PF07218.6 EXF84556.1 - 2.5 6.0 8.0 3.2 5.7 5.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Dicty_REP PF05086.7 EXF84556.1 - 4 5.0 4.7 4.7 4.8 3.3 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MgsA_C PF12002.3 EXF84557.1 - 4e-60 202.3 0.1 6.6e-60 201.6 0.1 1.3 1 0 0 1 1 1 1 MgsA AAA+ ATPase C terminal AAA PF00004.24 EXF84557.1 - 3e-13 50.1 0.0 7.2e-13 48.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EXF84557.1 - 2.4e-09 36.6 0.0 5.5e-09 35.4 0.0 1.5 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 EXF84557.1 - 2.9e-06 26.8 0.1 3.3e-05 23.4 0.0 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 EXF84557.1 - 3.2e-05 23.6 0.1 0.00066 19.4 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EXF84557.1 - 6.8e-05 22.9 1.3 0.0038 17.2 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EXF84557.1 - 0.00013 22.1 0.6 0.0011 19.0 0.2 2.5 2 1 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EXF84557.1 - 0.00023 20.4 0.1 0.12 11.5 0.0 2.2 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EXF84557.1 - 0.0006 19.5 0.0 0.0006 19.5 0.0 2.2 2 0 0 2 2 1 1 Part of AAA domain AAA_14 PF13173.1 EXF84557.1 - 0.0012 18.7 0.0 0.0021 17.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EXF84557.1 - 0.003 16.5 0.0 0.0048 15.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.8 EXF84557.1 - 0.0034 16.1 0.0 0.0061 15.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus ResIII PF04851.10 EXF84557.1 - 0.011 15.5 0.2 0.86 9.4 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.1 EXF84557.1 - 0.013 15.5 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain DNA_pol3_delta2 PF13177.1 EXF84557.1 - 0.028 14.0 0.0 2.2 7.9 0.0 2.5 2 1 1 3 3 2 0 DNA polymerase III, delta subunit AAA_3 PF07726.6 EXF84557.1 - 0.028 14.0 0.0 0.14 11.7 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SKI PF01202.17 EXF84557.1 - 0.075 12.8 0.1 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate kinase CPT PF07931.7 EXF84557.1 - 0.12 11.9 0.1 0.28 10.7 0.1 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein NB-ARC PF00931.17 EXF84557.1 - 0.14 10.9 0.0 0.22 10.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_10 PF12846.2 EXF84557.1 - 0.15 11.4 2.1 14 5.0 0.2 2.8 2 2 2 4 4 4 0 AAA-like domain AAA_17 PF13207.1 EXF84557.1 - 0.16 12.7 0.0 0.33 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Urease_beta PF00699.15 EXF84559.1 - 0.095 12.5 0.1 0.2 11.5 0.0 1.7 1 1 0 1 1 1 0 Urease beta subunit Invasin_D3 PF09134.5 EXF84559.1 - 0.13 12.1 0.2 11 5.9 0.0 2.1 2 0 0 2 2 2 0 Invasin, domain 3 Peptidase_M49 PF03571.10 EXF84560.1 - 6.8e-184 611.9 0.0 8e-184 611.7 0.0 1.0 1 0 0 1 1 1 1 Peptidase family M49 TPR_12 PF13424.1 EXF84562.1 - 4.9e-27 93.6 5.4 3.2e-11 43.0 0.0 6.4 4 1 2 6 6 6 3 Tetratricopeptide repeat NB-ARC PF00931.17 EXF84562.1 - 3.3e-23 81.9 0.0 5.4e-23 81.2 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain TPR_10 PF13374.1 EXF84562.1 - 3.2e-16 58.6 12.0 0.012 15.5 0.4 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 EXF84562.1 - 5e-11 42.0 1.4 1.9e-06 27.3 0.2 4.6 4 1 1 5 5 5 2 TPR repeat TPR_2 PF07719.12 EXF84562.1 - 1.2e-07 31.1 1.6 0.057 13.3 0.1 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.1 EXF84562.1 - 3.7e-06 27.0 5.2 1.8 9.4 0.0 6.4 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EXF84562.1 - 4.8e-06 25.9 3.3 0.0053 16.3 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EXF84562.1 - 0.00082 19.6 1.0 2.9 8.2 0.0 4.4 2 2 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EXF84562.1 - 0.0011 19.0 0.0 6.1 7.2 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EXF84562.1 - 0.0011 18.5 5.7 0.6 10.0 0.2 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat AAA_25 PF13481.1 EXF84562.1 - 0.0051 16.2 0.1 0.039 13.3 0.1 2.3 1 1 0 1 1 1 1 AAA domain PPR PF01535.15 EXF84562.1 - 0.0061 16.4 0.0 0.52 10.4 0.0 3.0 2 0 0 2 2 2 1 PPR repeat AAA_22 PF13401.1 EXF84562.1 - 0.008 16.3 0.1 0.039 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain TPR_8 PF13181.1 EXF84562.1 - 0.0084 15.8 0.1 22 5.1 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EXF84562.1 - 0.013 16.1 0.8 5.9 7.6 0.0 4.4 3 1 0 3 3 3 0 Tetratricopeptide repeat PPR_3 PF13812.1 EXF84562.1 - 0.034 14.4 0.2 16 6.1 0.0 3.6 3 0 0 3 3 3 0 Pentatricopeptide repeat domain TPR_6 PF13174.1 EXF84562.1 - 0.093 13.2 3.0 2.3e+02 2.5 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat Peptidase_S8 PF00082.17 EXF84564.1 - 5e-22 78.3 0.0 8.2e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 Subtilase family TPR_12 PF13424.1 EXF84564.1 - 4e-06 26.6 0.3 4e-06 26.6 0.2 2.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EXF84564.1 - 9.6e-06 24.9 0.4 0.00016 21.1 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EXF84564.1 - 0.00041 20.1 0.5 0.0016 18.2 0.0 2.3 2 0 0 2 2 1 1 Tetratricopeptide repeat TPR_7 PF13176.1 EXF84564.1 - 0.0011 18.5 0.2 0.054 13.3 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EXF84564.1 - 0.0013 18.4 0.2 0.0013 18.4 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EXF84564.1 - 0.0017 17.9 0.1 0.0083 15.8 0.1 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EXF84564.1 - 0.0063 16.1 0.0 0.033 13.8 0.0 2.2 2 0 0 2 2 2 1 TPR repeat CAF-1_p150 PF11600.3 EXF84564.1 - 0.017 14.4 47.1 0.041 13.2 32.6 1.7 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Apc3 PF12895.2 EXF84564.1 - 0.022 14.8 1.4 0.18 11.9 0.2 2.8 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EXF84564.1 - 0.041 14.5 2.4 0.14 12.9 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EXF84564.1 - 0.42 11.1 0.0 0.42 11.1 0.0 3.5 4 0 0 4 4 2 0 Tetratricopeptide repeat U79_P34 PF03064.11 EXF84564.1 - 5.8 6.3 27.2 11 5.4 18.9 1.5 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Herpes_gE PF02480.11 EXF84565.1 - 0.022 13.0 0.0 0.055 11.7 0.0 1.6 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E COesterase PF00135.23 EXF84569.1 - 7.4e-94 315.3 0.0 9.4e-94 315.0 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF84569.1 - 0.0013 18.3 0.1 0.0035 16.9 0.0 1.8 1 1 0 1 1 1 1 alpha/beta hydrolase fold Fungal_trans PF04082.13 EXF84570.1 - 3.9e-21 75.1 0.2 7.1e-21 74.2 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF84570.1 - 3.2e-06 26.9 6.7 6.3e-06 26.0 4.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EXF84571.1 - 1.6e-32 112.5 35.1 2.1e-32 112.2 24.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily ESSS PF10183.4 EXF84571.1 - 0.044 14.1 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) FMN_dh PF01070.13 EXF84573.1 - 5.2e-129 430.1 0.1 6e-129 429.9 0.1 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.20 EXF84573.1 - 5.5e-11 41.9 0.1 3.7e-10 39.2 0.0 2.3 2 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EXF84573.1 - 7.6e-10 38.4 0.5 1.2e-09 37.8 0.3 1.3 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 EXF84573.1 - 1.5e-06 27.4 0.4 0.00067 18.8 0.1 2.5 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.12 EXF84573.1 - 2.3e-06 26.8 0.6 4.1e-06 25.9 0.4 1.4 1 1 0 1 1 1 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EXF84573.1 - 3.3e-05 23.2 0.7 0.0048 16.1 0.0 2.4 1 1 1 2 2 2 2 Histidine biosynthesis protein DHO_dh PF01180.16 EXF84573.1 - 4.2e-05 22.6 0.5 0.00035 19.6 0.0 2.1 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase PcrB PF01884.12 EXF84573.1 - 6.9e-05 22.1 2.3 0.45 9.7 0.1 3.5 3 1 1 4 4 4 2 PcrB family Dus PF01207.12 EXF84573.1 - 0.00086 18.2 0.1 0.0022 16.8 0.0 1.7 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) IGPS PF00218.16 EXF84573.1 - 0.079 11.9 0.1 1.6 7.7 0.1 2.1 1 1 1 2 2 2 0 Indole-3-glycerol phosphate synthase G3P_antiterm PF04309.7 EXF84573.1 - 0.15 11.1 0.3 12 4.8 0.0 2.3 1 1 1 2 2 2 0 Glycerol-3-phosphate responsive antiterminator GST_C PF00043.20 EXF84574.1 - 1.6e-08 34.3 0.1 5.1e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EXF84574.1 - 3.8e-08 33.2 0.0 6.4e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EXF84574.1 - 2.2e-07 31.0 0.0 4.4e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EXF84574.1 - 2.5e-07 30.4 0.0 4.6e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EXF84574.1 - 5.7e-06 26.4 0.0 1.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EXF84574.1 - 0.0005 20.5 0.0 0.00092 19.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Sugarporin_N PF11471.3 EXF84574.1 - 0.13 11.9 1.0 0.22 11.1 0.7 1.3 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension p450 PF00067.17 EXF84575.1 - 5.6e-37 127.3 0.0 7.9e-37 126.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF1992 PF09350.5 EXF84576.1 - 2e-25 88.3 0.2 5.4e-25 87.0 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1992) TRCF PF03461.10 EXF84576.1 - 0.038 13.9 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 TRCF domain adh_short PF00106.20 EXF84577.1 - 1e-21 77.5 0.0 1.3e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF84577.1 - 2.1e-09 37.5 0.0 4.1e-09 36.5 0.0 1.4 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF84577.1 - 5.4e-06 26.1 0.0 9.3e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EXF84577.1 - 0.00052 20.0 0.3 0.00065 19.7 0.2 1.4 1 1 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EXF84577.1 - 0.0013 17.7 0.1 0.0023 16.9 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EXF84577.1 - 0.013 15.6 0.0 0.027 14.5 0.0 1.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.12 EXF84577.1 - 0.025 15.0 0.1 0.074 13.4 0.1 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DUF1776 PF08643.5 EXF84577.1 - 0.027 13.6 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EXF84577.1 - 0.035 13.5 0.1 0.051 13.0 0.1 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_2 PF03446.10 EXF84577.1 - 0.058 13.2 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 4HBT PF03061.17 EXF84578.1 - 1.3e-07 31.6 0.1 2.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily Acyl-CoA_dh_1 PF00441.19 EXF84579.1 - 8.7e-27 94.0 0.5 1.3e-26 93.5 0.4 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EXF84579.1 - 4.9e-22 78.6 0.1 1.5e-21 77.0 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EXF84579.1 - 1.7e-20 72.2 0.5 3.1e-20 71.4 0.4 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EXF84579.1 - 0.00023 21.4 0.4 0.0004 20.6 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AMP-binding PF00501.23 EXF84580.1 - 3.6e-05 22.3 0.2 0.0002 19.8 0.1 1.9 1 1 0 1 1 1 1 AMP-binding enzyme AMP-binding_C_2 PF14535.1 EXF84580.1 - 0.093 12.7 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain FA_desaturase PF00487.19 EXF84581.1 - 1.4e-24 86.9 21.7 2.5e-24 86.1 15.0 1.4 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EXF84581.1 - 6.4e-05 22.9 0.1 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) p450 PF00067.17 EXF84582.1 - 1.7e-63 214.7 0.0 2.3e-62 211.0 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Methyltransf_2 PF00891.13 EXF84583.1 - 1.8e-15 56.8 0.0 3.9e-15 55.7 0.0 1.5 1 1 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EXF84583.1 - 0.00053 20.5 0.1 0.0016 18.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EXF84583.1 - 0.001 18.4 0.0 0.0027 17.1 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Dimerisation PF08100.6 EXF84583.1 - 0.0014 18.4 0.1 0.004 16.9 0.1 1.8 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_25 PF13649.1 EXF84583.1 - 0.0047 17.2 0.0 0.011 16.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF84583.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EXF84583.1 - 0.018 14.7 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain MarR PF01047.17 EXF84583.1 - 0.067 12.9 0.1 0.65 9.7 0.0 2.3 2 0 0 2 2 2 0 MarR family Methyltransf_12 PF08242.7 EXF84583.1 - 0.08 13.4 0.0 0.23 11.9 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Thymidylat_synt PF00303.14 EXF84583.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.3 1 0 0 1 1 1 0 Thymidylate synthase Methyltransf_16 PF10294.4 EXF84583.1 - 0.13 11.6 0.0 0.39 10.1 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase zf-C2H2_4 PF13894.1 EXF84584.1 - 6.9e-08 32.2 9.0 0.0014 18.8 2.0 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger FAD_binding_3 PF01494.14 EXF84584.1 - 2.2e-07 30.2 0.0 4.2e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain zf-C2H2 PF00096.21 EXF84584.1 - 5.2e-07 29.6 10.3 0.0013 18.9 2.3 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EXF84584.1 - 6.7e-07 29.2 8.9 0.00017 21.6 0.5 3.3 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EXF84584.1 - 0.0012 18.8 0.3 0.3 11.2 0.4 2.6 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EXF84584.1 - 0.0019 18.0 5.9 0.21 11.5 0.1 2.8 3 0 0 3 3 3 2 C2H2-type zinc finger zf-Di19 PF05605.7 EXF84584.1 - 0.0033 17.4 2.2 0.0087 16.1 1.6 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding FYDLN_acid PF09538.5 EXF84584.1 - 1.3 9.5 4.4 1.3 9.6 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (FYDLN_acid) zf-C2HC_2 PF13913.1 EXF84584.1 - 3.4 7.4 7.9 4.3 7.1 2.0 2.5 2 0 0 2 2 2 0 zinc-finger of a C2HC-type HMG_CoA_synt_C PF08540.5 EXF84585.1 - 8.3e-91 304.3 0.2 1.1e-90 303.9 0.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EXF84585.1 - 6.7e-81 269.9 0.1 9.7e-81 269.4 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal 2OG-FeII_Oxy_2 PF13532.1 EXF84586.1 - 2.2e-15 57.0 0.0 3e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EXF84586.1 - 4.9e-11 42.7 0.0 7.9e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EXF84586.1 - 0.021 15.3 0.0 0.035 14.5 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily zf-AD PF07776.10 EXF84589.1 - 0.048 13.6 1.3 0.13 12.2 0.9 1.7 1 0 0 1 1 1 0 Zinc-finger associated domain (zf-AD) CHAD PF05235.9 EXF84590.1 - 0.022 14.3 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 CHAD domain Thi4 PF01946.12 EXF84591.1 - 1.2e-107 358.2 0.4 1.4e-107 357.9 0.3 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.19 EXF84591.1 - 7.1e-10 38.3 0.5 2.7e-08 33.1 0.7 2.1 1 1 1 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF84591.1 - 2.3e-05 23.4 0.8 9.2e-05 21.5 0.3 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EXF84591.1 - 5e-05 23.2 0.2 0.00012 22.0 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EXF84591.1 - 0.00016 21.4 0.8 0.00061 19.5 0.0 2.2 3 0 0 3 3 3 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EXF84591.1 - 0.00029 19.8 3.3 0.0044 15.9 0.7 2.3 2 1 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EXF84591.1 - 0.00081 19.3 0.1 0.0012 18.7 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF84591.1 - 0.0011 19.0 0.4 0.0018 18.3 0.3 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EXF84591.1 - 0.0074 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EXF84591.1 - 0.036 13.1 0.2 0.058 12.4 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Zn_clus PF00172.13 EXF84592.1 - 1.8e-05 24.5 14.4 3.8e-05 23.5 10.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF84592.1 - 0.00029 19.5 0.4 0.00041 19.0 0.3 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF4578 PF15147.1 EXF84592.1 - 0.042 14.2 0.1 1.2 9.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4578) p450 PF00067.17 EXF84593.1 - 5.4e-36 124.0 0.0 9.5e-36 123.2 0.0 1.3 1 0 0 1 1 1 1 Cytochrome P450 DUF2338 PF10100.4 EXF84593.1 - 0.065 11.5 0.0 0.092 11.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) Rxt3 PF08642.5 EXF84594.1 - 3e-27 95.1 0.0 6.3e-27 94.0 0.0 1.6 1 0 0 1 1 1 1 Histone deacetylation protein Rxt3 LCCL PF03815.14 EXF84594.1 - 0.00023 21.1 0.0 0.0081 16.1 0.0 2.3 2 0 0 2 2 2 1 LCCL domain DUF1674 PF07896.7 EXF84595.1 - 1.8e-15 56.8 3.2 3.5e-15 55.9 2.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) DUF3439 PF11921.3 EXF84595.1 - 0.027 14.2 5.0 0.038 13.7 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 EXF84595.1 - 0.12 12.1 14.7 0.17 11.6 10.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 EXF84595.1 - 0.43 8.4 13.6 0.52 8.2 9.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Med3 PF11593.3 EXF84595.1 - 8.7 5.4 14.4 11 5.1 10.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Glyco_hydro_43 PF04616.9 EXF84597.1 - 6.6e-32 110.7 1.9 7.9e-32 110.4 1.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 PA_decarbox PF05870.6 EXF84602.1 - 2.7e-09 36.7 0.2 4.1e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 Phenolic acid decarboxylase (PAD) DUF2855 PF11017.3 EXF84603.1 - 8.2e-67 225.5 0.0 9.5e-67 225.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) ADH_N PF08240.7 EXF84604.1 - 2.3e-25 88.4 7.4 4.5e-25 87.5 5.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF84604.1 - 3.2e-22 78.4 0.0 2.8e-21 75.4 0.0 2.6 3 1 0 3 3 3 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EXF84604.1 - 0.0021 17.2 0.1 0.0037 16.4 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 EXF84604.1 - 0.0027 18.5 0.0 0.0053 17.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EXF84604.1 - 0.0028 17.2 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.11 EXF84604.1 - 0.028 13.8 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA PhyH PF05721.8 EXF84606.1 - 7.4e-05 22.8 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) AAL_decarboxy PF03306.8 EXF84606.1 - 0.016 14.2 0.0 0.019 14.0 0.0 1.0 1 0 0 1 1 1 0 Alpha-acetolactate decarboxylase PhyH PF05721.8 EXF84607.1 - 4e-15 56.4 0.0 4.5e-15 56.2 0.0 1.0 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Acetyltransf_1 PF00583.19 EXF84608.1 - 6.3e-06 26.1 0.0 1.1e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EXF84608.1 - 0.001 19.1 0.0 0.0048 17.0 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Zn_clus PF00172.13 EXF84609.1 - 1.2e-05 25.0 7.7 3.9e-05 23.4 5.3 1.9 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF84609.1 - 1.2e-05 24.0 0.4 0.017 13.7 0.0 2.1 2 0 0 2 2 2 2 Fungal specific transcription factor domain Chloroa_b-bind PF00504.16 EXF84609.1 - 0.062 13.5 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Chlorophyll A-B binding protein NUDIX PF00293.23 EXF84610.1 - 5.1e-14 52.0 0.0 6.3e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.1 EXF84610.1 - 0.00054 19.3 0.0 0.00065 19.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotide hydrolase NUDIX_4 PF14815.1 EXF84610.1 - 0.0082 15.5 0.0 1.3 8.4 0.0 2.2 2 0 0 2 2 2 2 NUDIX domain Alph_Pro_TM PF09608.5 EXF84610.1 - 0.037 13.5 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative transmembrane protein (Alph_Pro_TM) NACHT PF05729.7 EXF84611.1 - 1.2e-07 31.5 0.0 2.7e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EXF84611.1 - 2.7e-05 24.3 0.1 0.00034 20.7 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EXF84611.1 - 0.00016 21.7 0.3 0.0011 18.9 0.0 2.5 2 1 0 2 2 2 1 AAA ATPase domain AAA_10 PF12846.2 EXF84611.1 - 0.00024 20.6 1.4 0.014 14.8 0.1 2.4 2 0 0 2 2 2 1 AAA-like domain AAA_25 PF13481.1 EXF84611.1 - 0.0012 18.3 0.0 0.0048 16.3 0.0 2.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EXF84611.1 - 0.0025 18.6 0.1 0.013 16.2 0.0 2.4 2 0 0 2 2 1 1 AAA domain RNA_helicase PF00910.17 EXF84611.1 - 0.0054 16.8 0.1 0.038 14.1 0.0 2.3 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.22 EXF84611.1 - 0.0083 16.4 1.6 0.026 14.8 0.0 2.4 2 1 0 2 2 2 1 ABC transporter AAA PF00004.24 EXF84611.1 - 0.037 14.2 0.0 0.17 12.0 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EXF84611.1 - 0.044 14.0 0.6 0.19 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EXF84611.1 - 0.048 13.6 0.0 0.2 11.6 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.1 EXF84611.1 - 0.053 13.8 4.9 0.26 11.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain Miro PF08477.8 EXF84611.1 - 0.089 13.2 0.0 0.26 11.7 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein cobW PF02492.14 EXF84611.1 - 0.14 11.6 0.0 0.26 10.7 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EXF84611.1 - 0.15 11.6 0.1 0.36 10.4 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Peptidase_M54 PF07998.6 EXF84612.1 - 7.7e-09 35.6 0.0 1.7e-08 34.4 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M54 Serglycin PF04360.7 EXF84612.1 - 0.013 15.2 1.1 0.027 14.1 0.8 1.5 1 0 0 1 1 1 0 Serglycin Peptidase_M10 PF00413.19 EXF84612.1 - 0.014 15.1 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 Matrixin FRQ PF09421.5 EXF84612.1 - 0.062 11.0 2.3 0.087 10.5 1.6 1.1 1 0 0 1 1 1 0 Frequency clock protein Peptidase_M57 PF12388.3 EXF84612.1 - 0.3 10.3 1.3 0.5 9.6 0.1 1.9 3 0 0 3 3 3 0 Dual-action HEIGH metallo-peptidase PDE8 PF08629.5 EXF84614.1 - 0.24 11.2 0.5 0.24 11.2 0.3 1.7 2 0 0 2 2 2 0 PDE8 phosphodiesterase HET PF06985.6 EXF84618.1 - 5.4e-15 55.7 0.0 1e-14 54.9 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) FliX PF10768.4 EXF84619.1 - 0.06 13.5 1.9 0.081 13.1 1.3 1.3 1 0 0 1 1 1 0 Class II flagellar assembly regulator SRA1 PF07304.6 EXF84619.1 - 0.097 12.4 0.4 0.18 11.5 0.1 1.5 1 1 0 1 1 1 0 Steroid receptor RNA activator (SRA1) DUF4398 PF14346.1 EXF84619.1 - 1.3 9.1 8.0 1.2 9.2 4.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4398) BTB PF00651.26 EXF84622.1 - 2.4e-10 40.3 0.2 8.9e-10 38.5 0.2 2.0 1 1 0 1 1 1 1 BTB/POZ domain SET PF00856.23 EXF84623.1 - 1.1e-07 32.2 0.1 2.8e-07 30.9 0.0 1.6 2 0 0 2 2 2 1 SET domain DUF3723 PF12520.3 EXF84624.1 - 4.4e-07 28.7 0.0 5.5e-07 28.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3723) DUF3723 PF12520.3 EXF84625.1 - 5.7e-57 193.3 4.9 1e-56 192.5 0.1 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3723) MRP-S26 PF14943.1 EXF84625.1 - 0.041 13.4 1.3 0.047 13.2 0.3 1.5 2 0 0 2 2 2 0 Mitochondrial ribosome subunit S26 DUF3723 PF12520.3 EXF84626.1 - 2.3e-63 214.4 3.6 1.7e-61 208.3 2.5 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF3723) DUF2205 PF10224.4 EXF84627.1 - 8.4e-31 105.3 0.3 1.4e-30 104.6 0.2 1.4 1 0 0 1 1 1 1 Predicted coiled-coil protein (DUF2205) AAA_32 PF13654.1 EXF84627.1 - 0.013 14.1 0.2 0.018 13.7 0.2 1.1 1 0 0 1 1 1 0 AAA domain Nramp PF01566.13 EXF84628.1 - 6.3e-92 308.1 12.6 6.3e-92 308.1 8.8 1.4 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Ribonuc_L-PSP PF01042.16 EXF84628.1 - 6.6e-21 74.3 0.0 1.2e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Endoribonuclease L-PSP Fungal_trans PF04082.13 EXF84630.1 - 4.3e-25 88.0 0.1 6.5e-25 87.4 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF84630.1 - 7.8e-07 28.9 11.6 1.8e-06 27.7 8.0 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF84630.1 - 0.012 14.2 0.1 0.1 11.1 0.0 2.3 2 1 0 3 3 3 0 Fungal specific transcription factor domain Luteo_Vpg PF01659.11 EXF84630.1 - 0.08 12.6 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Luteovirus putative VPg genome linked protein Bac_rhodopsin PF01036.13 EXF84631.1 - 1e-60 204.7 12.8 1.3e-60 204.5 8.8 1.0 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein Cytochrom_B561 PF03188.11 EXF84631.1 - 3.2 7.5 11.0 6.1 6.6 1.1 2.2 2 0 0 2 2 2 0 Eukaryotic cytochrome b561 RPE65 PF03055.10 EXF84632.1 - 4.6e-136 454.2 0.0 5.2e-136 454.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein E1-E2_ATPase PF00122.15 EXF84633.1 - 3.9e-64 215.8 7.6 3.9e-64 215.8 5.3 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EXF84633.1 - 6e-31 107.3 5.4 6e-31 107.3 3.8 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EXF84633.1 - 3.9e-27 96.0 0.0 1.7e-25 90.7 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EXF84633.1 - 1e-15 57.4 0.0 1.9e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EXF84633.1 - 4e-15 55.0 0.0 9.7e-15 53.7 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EXF84633.1 - 6.6e-13 49.2 0.0 1.6e-12 47.9 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EXF84633.1 - 4.3e-06 26.5 1.7 6e-05 22.7 0.5 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Sulfotransfer_3 PF13469.1 EXF84634.1 - 7.3e-06 26.9 0.8 1.2e-05 26.3 0.6 1.4 1 1 0 1 1 1 1 Sulfotransferase family HsbA PF12296.3 EXF84635.1 - 3.8e-17 62.3 13.6 3.8e-17 62.3 9.4 1.8 2 0 0 2 2 2 1 Hydrophobic surface binding protein A Sec8_exocyst PF04048.9 EXF84635.1 - 0.0028 17.3 1.0 0.0054 16.3 0.7 1.4 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain RRF_GI PF12614.3 EXF84635.1 - 0.035 13.9 0.1 0.083 12.7 0.1 1.6 1 0 0 1 1 1 0 Ribosome recycling factor NPV_P10 PF05531.7 EXF84635.1 - 0.038 14.2 11.7 0.53 10.5 1.3 2.9 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 EXF84635.1 - 0.054 13.2 4.1 0.25 11.0 0.5 2.3 1 1 1 2 2 2 0 Laminin Domain II DUF4404 PF14357.1 EXF84635.1 - 0.078 13.3 1.0 0.2 12.0 0.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) Sas10_Utp3 PF04000.10 EXF84635.1 - 0.091 12.9 2.3 1.1 9.4 1.6 2.4 1 1 0 1 1 1 0 Sas10/Utp3/C1D family ApoLp-III PF07464.6 EXF84635.1 - 0.12 12.3 6.6 0.19 11.7 3.3 2.0 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) TrbC PF04956.8 EXF84635.1 - 2 8.4 9.6 0.15 12.0 0.7 3.0 2 2 1 3 3 3 0 TrbC/VIRB2 family HET PF06985.6 EXF84636.1 - 1.6e-19 70.4 5.2 4.3e-16 59.3 0.8 2.3 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) SNF2_N PF00176.18 EXF84638.1 - 1.4e-74 250.6 0.7 1.4e-74 250.6 0.5 1.6 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EXF84638.1 - 1.1e-14 54.0 0.0 3.3e-14 52.4 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EXF84638.1 - 3.4e-08 33.5 0.0 8e-08 32.3 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.3 EXF84638.1 - 8e-05 21.5 0.2 0.26 10.0 0.0 2.6 2 1 0 2 2 2 2 Class II histone deacetylase complex subunits 2 and 3 DEAD PF00270.24 EXF84638.1 - 0.00025 20.5 0.0 0.00049 19.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase HSA PF07529.8 EXF84638.1 - 0.0068 16.1 6.9 0.0068 16.1 4.8 2.4 2 0 0 2 2 2 1 HSA NDUF_B8 PF05821.6 EXF84639.1 - 1.1e-05 25.1 0.0 1.3e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) Glyco_hydro_1 PF00232.13 EXF84641.1 - 1.2e-74 251.1 0.0 5.7e-74 248.9 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 Cellulase PF00150.13 EXF84641.1 - 0.0088 15.2 0.2 0.031 13.4 0.0 1.8 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) AMP-binding PF00501.23 EXF84642.1 - 4.7e-23 81.2 0.0 1.1e-22 79.9 0.0 1.6 1 1 0 1 1 1 1 AMP-binding enzyme ADH_N PF08240.7 EXF84643.1 - 1.7e-05 24.5 0.0 0.00034 20.3 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF4634 PF15465.1 EXF84643.1 - 0.2 11.8 0.3 0.43 10.7 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4634) MFS_1 PF07690.11 EXF84644.1 - 1.3e-35 122.8 68.0 3.9e-35 121.1 45.5 2.9 2 1 0 2 2 2 1 Major Facilitator Superfamily ASFV_L11L PF05293.6 EXF84644.1 - 0.026 14.6 1.3 0.13 12.4 0.9 2.2 1 0 0 1 1 1 0 African swine fever virus (ASFV) L11L protein InaF-motif PF15018.1 EXF84644.1 - 1 8.8 7.3 0.37 10.2 0.2 3.1 2 0 0 2 2 2 0 TRP-interacting helix F-box-like PF12937.2 EXF84645.1 - 0.0017 18.0 0.5 0.004 16.8 0.3 1.7 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EXF84645.1 - 0.051 13.2 0.2 0.051 13.2 0.2 3.6 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EXF84645.1 - 3.1 8.3 6.8 1.8e+02 3.0 0.3 5.0 4 1 1 5 5 5 0 Leucine rich repeat p450 PF00067.17 EXF84646.1 - 6.9e-49 166.6 0.0 1.1e-48 165.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Acyl_transf_1 PF00698.16 EXF84646.1 - 0.064 12.5 0.1 0.12 11.6 0.0 1.4 2 0 0 2 2 2 0 Acyl transferase domain Trehalase_Ca-bi PF07492.6 EXF84646.1 - 0.18 11.1 1.9 0.31 10.3 1.3 1.3 1 0 0 1 1 1 0 Neutral trehalase Ca2+ binding domain NAD_binding_8 PF13450.1 EXF84647.1 - 2.2e-14 53.1 0.1 5.2e-14 52.0 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EXF84647.1 - 2e-10 40.3 0.0 4.8e-10 39.0 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_oxidored PF12831.2 EXF84647.1 - 2.6e-08 33.4 0.0 2.8e-06 26.7 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF84647.1 - 1.2e-06 27.6 0.3 1.9e-06 27.0 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF84647.1 - 1.7e-06 27.1 0.2 0.00034 19.6 0.7 2.9 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EXF84647.1 - 7.9e-06 26.0 0.5 2.5e-05 24.4 0.0 2.0 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF84647.1 - 1.8e-05 23.4 0.3 3.3e-05 22.5 0.1 1.5 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EXF84647.1 - 0.0001 22.6 0.3 0.00069 19.9 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF84647.1 - 0.00051 19.9 0.1 0.0014 18.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF84647.1 - 0.0018 17.4 0.1 0.0052 15.8 0.0 1.7 2 0 0 2 2 2 1 Thi4 family ApbA PF02558.11 EXF84647.1 - 0.011 15.2 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_binding_3 PF01494.14 EXF84647.1 - 0.018 14.1 0.2 0.032 13.2 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain Lycopene_cycl PF05834.7 EXF84647.1 - 0.047 12.6 0.0 0.073 11.9 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.1 EXF84647.1 - 0.059 13.6 0.1 0.16 12.2 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding GIDA PF01134.17 EXF84647.1 - 0.096 11.5 0.2 0.14 10.9 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A MFS_1 PF07690.11 EXF84648.1 - 3e-25 88.7 29.9 3e-25 88.7 20.7 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF84648.1 - 7.2e-06 24.8 9.8 7.2e-06 24.8 6.8 3.4 2 2 1 3 3 3 1 Sugar (and other) transporter IBR PF01485.16 EXF84649.1 - 4.3e-12 45.7 33.6 4.4e-07 29.6 5.9 3.8 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 EXF84649.1 - 0.00045 20.0 9.6 0.00045 20.0 6.7 3.3 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EXF84649.1 - 0.0047 16.9 10.3 0.0047 16.9 7.2 3.7 2 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EXF84649.1 - 0.016 14.9 11.0 0.016 14.9 7.6 3.5 3 0 0 3 3 3 0 zinc-RING finger domain Pyr_excise PF03013.9 EXF84649.1 - 0.17 11.6 10.0 0.15 11.7 0.5 3.2 3 2 1 4 4 4 0 Pyrimidine dimer DNA glycosylase CorA PF01544.13 EXF84650.1 - 1.5e-13 50.4 0.2 2.6e-13 49.6 0.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein SR-25 PF10500.4 EXF84650.1 - 6 6.2 11.9 0.33 10.3 4.5 1.6 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein zf-H2C2_2 PF13465.1 EXF84653.1 - 1.4e-10 40.8 5.7 9.2e-07 28.8 0.9 2.8 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2 PF00096.21 EXF84653.1 - 6.5e-10 38.7 14.6 6.2e-05 23.1 1.2 2.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF84653.1 - 9.4e-09 34.9 8.3 0.00021 21.3 0.3 2.7 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EXF84653.1 - 0.003 17.6 7.2 0.018 15.2 1.6 2.6 2 0 0 2 2 2 1 C2H2-type zinc-finger domain zf-C2H2_jaz PF12171.3 EXF84653.1 - 0.0056 16.7 3.0 0.18 11.9 0.1 2.5 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding BolA PF01722.13 EXF84653.1 - 0.041 13.8 0.2 3.3 7.7 0.0 2.3 1 1 1 2 2 2 0 BolA-like protein zf-met PF12874.2 EXF84653.1 - 0.2 11.9 4.1 0.31 11.2 0.1 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-BED PF02892.10 EXF84653.1 - 0.38 10.5 2.5 1.2 8.8 0.1 2.3 2 0 0 2 2 2 0 BED zinc finger zf-C2H2_6 PF13912.1 EXF84653.1 - 6.7 6.7 12.6 2.9 7.9 0.4 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Radial_spoke PF04712.7 EXF84654.1 - 0.069 11.8 0.0 0.076 11.7 0.0 1.0 1 0 0 1 1 1 0 Radial spokehead-like protein Fungal_trans_2 PF11951.3 EXF84655.1 - 2.9e-22 78.8 0.2 3.4e-22 78.5 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain ATP-grasp_4 PF13535.1 EXF84656.1 - 6.7e-22 78.1 0.0 2.6e-19 69.6 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EXF84656.1 - 0.00052 18.8 0.0 0.25 10.0 0.0 2.2 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EXF84656.1 - 0.00098 18.5 0.0 0.0021 17.4 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.12 EXF84656.1 - 0.0033 16.7 0.0 0.0062 15.8 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GSH-S_ATP PF02955.11 EXF84656.1 - 0.0044 16.1 0.0 0.0074 15.4 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_3 PF02655.9 EXF84656.1 - 0.0055 16.5 0.0 0.12 12.1 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain p450 PF00067.17 EXF84657.1 - 2.8e-37 128.3 0.0 3.6e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Aminotran_3 PF00202.16 EXF84658.1 - 3.6e-83 279.2 0.1 4.3e-83 278.9 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EXF84658.1 - 0.034 13.1 0.1 0.096 11.6 0.0 1.7 2 0 0 2 2 2 0 Aminotransferase class I and II Ank PF00023.25 EXF84659.1 - 8.8e-23 78.9 5.1 5e-07 29.2 0.1 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EXF84659.1 - 1.9e-22 79.4 1.3 3.1e-22 78.7 0.9 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EXF84659.1 - 2.7e-18 65.9 2.5 2.4e-09 37.4 0.2 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF84659.1 - 1.2e-16 59.1 1.1 0.00012 21.9 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EXF84659.1 - 2e-12 46.9 3.7 9.7e-06 25.6 0.1 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) MFS_1 PF07690.11 EXF84660.1 - 1.1e-33 116.4 51.5 5.5e-24 84.5 20.2 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily adh_short PF00106.20 EXF84660.1 - 6.4e-20 71.7 0.3 1.4e-19 70.5 0.1 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EXF84660.1 - 1.5e-12 47.5 0.0 2.5e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF84660.1 - 1.4e-05 24.9 0.0 3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EXF84660.1 - 6.4e-05 22.4 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GFO_IDH_MocA PF01408.17 EXF84661.1 - 8e-06 26.3 0.0 2.3e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold NADH_B2 PF14813.1 EXF84661.1 - 0.085 12.5 0.3 0.26 10.9 0.2 1.7 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 adh_short PF00106.20 EXF84663.1 - 7.4e-16 58.5 3.5 9e-14 51.7 0.1 2.0 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 EXF84663.1 - 1.3e-08 34.7 0.6 2.2e-08 33.9 0.4 1.4 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF84663.1 - 3.1e-06 27.1 0.1 3.7e-06 26.8 0.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3HCDH_N PF02737.13 EXF84663.1 - 0.0023 17.5 0.1 0.0035 17.0 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MTS PF05175.9 EXF84663.1 - 0.0069 15.7 0.0 0.0084 15.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Eno-Rase_NADH_b PF12242.3 EXF84663.1 - 0.039 13.7 0.2 0.25 11.1 0.0 2.1 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ChuX_HutX PF06228.8 EXF84663.1 - 0.047 13.0 0.0 0.085 12.2 0.0 1.5 1 1 0 1 1 1 0 Haem utilisation ChuX/HutX Polysacc_synt_2 PF02719.10 EXF84663.1 - 0.053 12.4 0.1 0.054 12.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pellino PF04710.9 EXF84663.1 - 0.067 11.8 0.0 4.6 5.7 0.0 2.0 1 1 1 2 2 2 0 Pellino Ldh_1_N PF00056.18 EXF84663.1 - 0.2 11.5 2.7 0.61 9.9 0.8 2.3 2 1 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain MFS_1 PF07690.11 EXF84664.1 - 7.1e-28 97.3 69.0 2.1e-26 92.4 25.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily APOC4 PF15119.1 EXF84664.1 - 0.00071 19.5 0.0 0.0013 18.6 0.0 1.3 1 0 0 1 1 1 1 Apolipoprotein C4 Fungal_trans PF04082.13 EXF84665.1 - 2.3e-08 33.2 0.0 3.9e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF84665.1 - 5e-08 32.7 11.8 8.8e-08 31.9 8.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetate_kinase PF00871.12 EXF84666.1 - 8e-93 311.0 0.0 1e-92 310.7 0.0 1.1 1 0 0 1 1 1 1 Acetokinase family Sugar_tr PF00083.19 EXF84667.1 - 1.9e-30 105.8 26.7 1.2e-19 70.2 6.7 2.4 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.11 EXF84667.1 - 2.2e-22 79.2 25.5 2.5e-16 59.3 10.3 2.1 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF4181 PF13789.1 EXF84667.1 - 2.9 7.8 0.0 2.9 7.8 0.0 3.4 3 1 0 4 4 4 0 Domain of unknown function (DUF4181) Fungal_trans PF04082.13 EXF84668.1 - 8.9e-21 73.9 0.3 1.6e-20 73.0 0.2 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain GST_N_3 PF13417.1 EXF84668.1 - 1.8e-16 60.0 0.0 4.3e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EXF84668.1 - 2.1e-10 40.4 0.0 5.1e-10 39.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Zn_clus PF00172.13 EXF84668.1 - 8e-09 35.2 8.4 1.7e-08 34.1 5.8 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_C_2 PF13410.1 EXF84668.1 - 5.3e-05 23.0 0.5 0.00016 21.5 0.4 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EXF84668.1 - 0.15 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin WD40 PF00400.27 EXF84669.1 - 5.3e-28 95.8 9.6 3.3e-08 33.1 0.2 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 EXF84669.1 - 4.8e-05 21.7 0.6 0.0099 14.0 0.1 2.9 2 1 0 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 EXF84669.1 - 0.014 15.1 0.0 0.38 10.4 0.0 2.9 2 2 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF1513 PF07433.6 EXF84669.1 - 0.1 11.5 0.0 0.47 9.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) RIC1 PF07064.8 EXF84671.1 - 2.7e-88 295.7 0.1 3.8e-88 295.2 0.1 1.2 1 0 0 1 1 1 1 RIC1 WD40 PF00400.27 EXF84671.1 - 5.4e-05 22.9 0.4 1 9.3 0.0 4.7 4 0 0 4 4 4 2 WD domain, G-beta repeat CK_II_beta PF01214.13 EXF84672.1 - 8.8e-73 243.7 0.1 1.1e-72 243.4 0.1 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit PAP2 PF01569.16 EXF84673.1 - 4.2e-20 71.7 2.0 4.2e-20 71.7 1.4 2.0 2 0 0 2 2 2 1 PAP2 superfamily DUF4386 PF14329.1 EXF84673.1 - 0.023 14.1 1.5 0.023 14.1 1.0 3.3 4 1 1 5 5 5 0 Domain of unknown function (DUF4386) Polysacc_deac_1 PF01522.16 EXF84674.1 - 2.5e-27 94.9 0.0 8.3e-27 93.2 0.0 1.8 2 0 0 2 2 2 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EXF84674.1 - 8.4e-18 64.0 64.2 2.1e-07 30.7 8.2 3.8 3 0 0 3 3 3 3 Chitin recognition protein Cyclin_N PF00134.18 EXF84675.1 - 1e-43 147.9 0.0 4.2e-43 145.9 0.0 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EXF84675.1 - 4.1e-33 113.8 0.0 7.4e-33 112.9 0.0 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ribosomal_L2_C PF03947.13 EXF84676.1 - 9.9e-45 151.5 5.3 2e-44 150.5 1.7 2.8 2 1 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EXF84676.1 - 6.7e-27 93.2 0.3 1.4e-26 92.2 0.2 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain DUF3987 PF13148.1 EXF84677.1 - 0.00032 19.3 1.0 0.00036 19.2 0.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) RGS-like PF09128.6 EXF84677.1 - 0.0018 17.8 0.0 0.002 17.6 0.0 1.1 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain NinG PF05766.7 EXF84677.1 - 0.002 17.8 0.3 0.0025 17.6 0.2 1.0 1 0 0 1 1 1 1 Bacteriophage Lambda NinG protein PEP-utilisers_N PF05524.8 EXF84677.1 - 0.034 13.9 0.4 0.046 13.5 0.3 1.2 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal OHCU_decarbox PF09349.5 EXF84677.1 - 0.065 13.5 1.1 0.098 12.9 0.8 1.3 1 0 0 1 1 1 0 OHCU decarboxylase VIT1 PF01988.14 EXF84677.1 - 0.13 11.7 0.1 0.15 11.5 0.0 1.1 1 0 0 1 1 1 0 VIT family Peptidase_S49_N PF08496.5 EXF84677.1 - 0.42 10.3 3.0 0.59 9.9 2.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4407 PF14362.1 EXF84677.1 - 0.94 8.3 3.6 1.1 8.0 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ion_trans PF00520.26 EXF84679.1 - 2.8e-103 343.3 77.3 9.5e-35 119.6 8.2 5.2 4 1 0 4 4 4 4 Ion transport protein PKD_channel PF08016.7 EXF84679.1 - 0.0015 17.0 56.0 0.0099 14.3 1.5 6.9 5 1 1 6 6 6 6 Polycystin cation channel JSRP PF15312.1 EXF84679.1 - 0.0049 16.8 0.1 0.02 14.8 0.1 2.1 1 0 0 1 1 1 1 Junctional sarcoplasmic reticulum protein PHD PF00628.24 EXF84680.1 - 1.8e-09 37.1 9.2 3.9e-09 36.0 6.4 1.6 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.1 EXF84680.1 - 0.0091 15.2 6.3 0.019 14.2 4.3 1.5 1 0 0 1 1 1 1 PHD-finger DUF2454 PF10521.4 EXF84680.1 - 0.45 9.4 3.6 0.69 8.8 2.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2454) PI31_Prot_C PF08577.6 EXF84681.1 - 0.052 14.1 0.2 0.076 13.6 0.2 1.3 1 0 0 1 1 1 0 PI31 proteasome regulator HMG_box PF00505.14 EXF84682.1 - 8.7e-14 51.5 0.3 1.5e-12 47.5 0.1 2.4 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EXF84682.1 - 0.00069 19.9 0.0 0.0016 18.7 0.0 1.7 1 0 0 1 1 1 1 HMG-box domain MAT_Alpha1 PF04769.7 EXF84682.1 - 0.0056 16.0 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Mating-type protein MAT alpha 1 MMgT PF10270.4 EXF84683.1 - 5.3e-30 103.9 0.0 6.1e-30 103.7 0.0 1.0 1 0 0 1 1 1 1 Membrane magnesium transporter MutS_V PF00488.16 EXF84684.1 - 3e-54 183.9 0.1 6.1e-54 182.9 0.0 1.5 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.13 EXF84684.1 - 4.5e-23 82.1 0.1 7.8e-23 81.3 0.1 1.4 1 0 0 1 1 1 1 MutS domain III CorA PF01544.13 EXF84685.1 - 1.2e-06 27.8 0.4 2.6e-06 26.7 0.3 1.7 1 1 0 1 1 1 1 CorA-like Mg2+ transporter protein Nitrophorin PF02087.10 EXF84685.1 - 0.12 12.1 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Nitrophorin MmgE_PrpD PF03972.9 EXF84687.1 - 0.043 11.9 0.2 0.078 11.1 0.1 1.4 1 0 0 1 1 1 0 MmgE/PrpD family WD40 PF00400.27 EXF84689.1 - 1.2e-12 47.1 1.6 0.89 9.5 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat A_deaminase PF00962.17 EXF84690.1 - 4.8e-111 370.8 0.1 6.4e-111 370.4 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase UAA PF08449.6 EXF84690.1 - 1.2e-97 326.5 5.8 1.6e-97 326.0 4.0 1.2 1 0 0 1 1 1 1 UAA transporter family Nuc_sug_transp PF04142.10 EXF84690.1 - 4.3e-06 26.0 0.1 9.9e-06 24.8 0.1 1.5 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 EXF84690.1 - 5.1 6.7 11.2 0.049 13.2 1.0 2.2 2 0 0 2 2 2 0 Triose-phosphate Transporter family EmrE PF13536.1 EXF84690.1 - 5.7 7.1 17.4 1 9.5 2.2 3.2 2 1 1 3 3 3 0 Multidrug resistance efflux transporter SHD1 PF03983.7 EXF84691.1 - 4.6e-37 125.5 0.1 8.4e-37 124.6 0.0 1.4 1 0 0 1 1 1 1 SLA1 homology domain 1, SHD1 SH3_1 PF00018.23 EXF84691.1 - 3.8e-33 112.6 9.3 7.4e-13 47.6 0.1 4.3 4 0 0 4 4 4 3 SH3 domain SH3_9 PF14604.1 EXF84691.1 - 3.5e-32 109.7 9.9 1.7e-11 43.4 0.2 3.9 4 0 0 4 4 4 3 Variant SH3 domain SH3_2 PF07653.12 EXF84691.1 - 3e-23 81.0 0.6 2.3e-07 30.2 0.0 4.3 4 0 0 4 4 4 3 Variant SH3 domain SH3_3 PF08239.6 EXF84691.1 - 2.8e-07 30.6 4.4 0.0098 16.0 0.3 3.5 3 0 0 3 3 3 3 Bacterial SH3 domain DUF1720 PF08226.6 EXF84691.1 - 0.00018 21.5 33.6 0.00018 21.5 23.3 5.9 1 1 3 4 4 4 1 Domain of unknown function (DUF1720) TRAM_LAG1_CLN8 PF03798.11 EXF84692.1 - 3.3e-46 157.3 15.5 3.3e-46 157.3 10.7 1.5 2 0 0 2 2 2 1 TLC domain Dor1 PF04124.7 EXF84693.1 - 3.2e-56 190.2 2.0 2.8e-45 154.2 2.5 2.1 2 0 0 2 2 2 2 Dor1-like family Mito_carr PF00153.22 EXF84694.1 - 7.3e-52 173.0 2.2 2.7e-19 68.6 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Prefoldin_2 PF01920.15 EXF84696.1 - 4.7e-18 64.8 2.8 5.4e-18 64.7 1.8 1.2 1 1 0 1 1 1 1 Prefoldin subunit TMF_TATA_bd PF12325.3 EXF84696.1 - 0.00024 20.7 2.1 0.0012 18.5 0.1 2.0 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding DUF2730 PF10805.3 EXF84696.1 - 0.07 12.8 1.2 0.8 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) CENP-Q PF13094.1 EXF84696.1 - 0.085 12.8 3.4 0.11 12.4 0.2 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF641 PF04859.7 EXF84696.1 - 0.18 11.5 3.3 0.67 9.7 0.1 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) USP8_interact PF08941.5 EXF84696.1 - 0.29 10.4 2.3 0.2 10.9 0.1 1.7 2 0 0 2 2 2 0 USP8 interacting FliJ PF02050.11 EXF84696.1 - 0.4 10.7 10.2 3.2 7.8 2.1 2.1 2 0 0 2 2 2 0 Flagellar FliJ protein TBPIP PF07106.8 EXF84696.1 - 0.44 10.0 6.0 0.51 9.8 0.6 2.0 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Sipho_Gp157 PF05565.6 EXF84696.1 - 0.5 9.9 4.4 1.9 8.0 0.2 2.0 2 0 0 2 2 2 0 Siphovirus Gp157 DUF4200 PF13863.1 EXF84696.1 - 0.66 9.9 7.4 3.8 7.4 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) MscS_porin PF12795.2 EXF84696.1 - 0.71 9.1 11.6 0.27 10.5 2.5 2.0 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain TMF_DNA_bd PF12329.3 EXF84696.1 - 0.75 9.6 8.9 0.19 11.5 2.2 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Striatin PF08232.7 EXF84696.1 - 0.93 9.8 6.4 0.53 10.6 1.1 2.0 2 0 0 2 2 2 0 Striatin family THOC7 PF05615.8 EXF84696.1 - 1.5 9.0 5.6 11 6.2 0.4 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 PspA_IM30 PF04012.7 EXF84696.1 - 2.3 7.5 10.5 2.9 7.2 1.8 2.0 2 0 0 2 2 2 0 PspA/IM30 family FliD_C PF07195.7 EXF84696.1 - 4.6 6.4 6.1 1.5 8.0 0.4 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 C-terminus DUF2681 PF10883.3 EXF84696.1 - 8.8 6.6 8.5 16 5.7 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Atg14 PF10186.4 EXF84696.1 - 10 4.9 8.2 90 1.8 5.7 1.9 1 1 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Ceramidase PF05875.7 EXF84697.1 - 3.3e-87 291.9 9.4 4.1e-87 291.6 6.5 1.0 1 0 0 1 1 1 1 Ceramidase Arv1 PF04161.8 EXF84697.1 - 0.026 14.4 0.8 0.046 13.6 0.5 1.4 1 1 0 1 1 1 0 Arv1-like family DsbB PF02600.11 EXF84697.1 - 4.7 6.9 10.0 12 5.7 2.4 3.0 1 1 2 3 3 3 0 Disulfide bond formation protein DsbB TMF_TATA_bd PF12325.3 EXF84698.1 - 2.9e-41 139.9 8.7 2.9e-41 139.9 6.0 6.2 3 2 4 7 7 7 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EXF84698.1 - 6.3e-15 54.7 0.7 6.3e-15 54.7 0.5 8.4 4 3 4 8 8 8 1 TATA element modulatory factor 1 DNA binding Tropomyosin_1 PF12718.2 EXF84698.1 - 0.01 15.6 10.6 0.01 15.6 7.4 5.3 3 1 2 5 5 5 0 Tropomyosin like Phage_GP20 PF06810.6 EXF84698.1 - 0.012 15.0 1.4 0.012 15.0 1.0 4.9 3 1 1 5 5 5 0 Phage minor structural protein GP20 DivIC PF04977.10 EXF84698.1 - 0.019 14.4 0.3 0.019 14.4 0.2 8.2 4 3 4 8 8 8 0 Septum formation initiator COG5 PF10392.4 EXF84698.1 - 0.022 14.7 0.9 0.022 14.7 0.6 4.1 3 1 1 4 4 4 0 Golgi transport complex subunit 5 Reo_sigmaC PF04582.7 EXF84698.1 - 0.09 11.9 17.9 0.81 8.7 2.2 4.0 2 1 2 4 4 4 0 Reovirus sigma C capsid protein ATG16 PF08614.6 EXF84698.1 - 0.42 10.4 64.8 0.024 14.4 1.8 5.2 2 1 1 4 4 4 0 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.4 EXF84698.1 - 1 9.2 64.1 0.25 11.1 3.9 5.6 4 1 0 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.6 EXF84698.1 - 2.7 7.9 24.6 0.73 9.7 1.4 5.5 7 0 0 7 7 7 0 Flagella accessory protein C (FlaC) DUF3584 PF12128.3 EXF84698.1 - 4.3 4.5 67.7 1.5 6.0 10.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3584) IncA PF04156.9 EXF84698.1 - 5.6 6.5 65.5 0.041 13.4 2.4 5.4 3 1 1 4 4 4 0 IncA protein Ank_2 PF12796.2 EXF84699.1 - 1.8e-45 153.2 1.2 3.6e-19 68.8 0.7 2.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EXF84699.1 - 1.8e-38 129.6 4.7 2.6e-10 40.1 0.4 5.6 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 EXF84699.1 - 2.1e-33 112.4 4.5 2.9e-06 26.7 0.2 6.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 EXF84699.1 - 1.3e-31 108.3 3.2 5.4e-10 39.5 0.1 5.1 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF84699.1 - 3.9e-29 97.7 0.1 0.003 17.6 0.0 6.7 7 0 0 7 7 7 6 Ankyrin repeat Chlorophyllase PF07224.6 EXF84699.1 - 0.072 11.8 0.0 0.082 11.6 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase WD40 PF00400.27 EXF84700.1 - 1.2e-53 177.1 16.3 1.4e-09 37.4 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EXF84700.1 - 0.00044 18.5 4.8 2.7 6.0 0.5 4.8 1 1 2 3 3 3 3 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EXF84700.1 - 0.0073 15.7 0.6 3.8 6.9 0.1 2.8 2 1 0 3 3 3 2 PQQ-like domain AAA PF00004.24 EXF84701.1 - 6.7e-16 58.6 0.0 1e-14 54.8 0.0 2.5 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EXF84701.1 - 9.7e-11 41.9 0.0 1.4e-09 38.1 0.0 2.6 1 1 0 1 1 1 1 AAA ATPase domain BAH PF01426.13 EXF84701.1 - 2.5e-09 36.9 0.0 1.2e-08 34.6 0.0 2.0 2 0 0 2 2 2 1 BAH domain AAA_22 PF13401.1 EXF84701.1 - 7.5e-09 35.8 0.0 6.3e-07 29.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EXF84701.1 - 0.00023 20.8 0.1 0.00083 19.0 0.0 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_17 PF13207.1 EXF84701.1 - 0.0024 18.6 0.0 0.041 14.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain Arch_ATPase PF01637.13 EXF84701.1 - 0.0024 17.6 0.0 0.026 14.2 0.0 2.4 1 1 0 1 1 1 1 Archaeal ATPase DUF2075 PF09848.4 EXF84701.1 - 0.0037 16.2 0.0 0.0058 15.6 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 EXF84701.1 - 0.0081 15.8 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_11 PF13086.1 EXF84701.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EXF84701.1 - 0.023 15.0 0.0 0.052 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain Zot PF05707.7 EXF84701.1 - 0.039 13.4 0.0 0.074 12.5 0.0 1.4 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) AAA_32 PF13654.1 EXF84701.1 - 0.048 12.3 0.0 0.072 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EXF84701.1 - 0.1 12.7 0.0 0.41 10.8 0.0 2.1 2 0 0 2 2 2 0 RNA helicase NTPase_1 PF03266.10 EXF84701.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.7 1 0 0 1 1 1 0 NTPase Baculo_11_kDa PF06143.6 EXF84701.1 - 0.21 10.9 0.0 0.47 9.8 0.0 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family tRNA-synt_1 PF00133.17 EXF84702.1 - 1.9e-218 726.3 0.0 4.7e-218 725.0 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EXF84702.1 - 3.7e-26 91.6 0.0 1.1e-25 90.1 0.0 1.8 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EXF84702.1 - 2.6e-18 65.8 0.0 2e-07 30.0 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EXF84702.1 - 0.0063 15.6 0.1 0.054 12.6 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Mo25 PF08569.6 EXF84703.1 - 3.5e-126 420.7 0.1 4e-126 420.6 0.0 1.0 1 0 0 1 1 1 1 Mo25-like DNA_topoisoIV PF00521.15 EXF84703.1 - 0.037 12.8 0.1 0.074 11.8 0.0 1.4 2 0 0 2 2 2 0 DNA gyrase/topoisomerase IV, subunit A RepA_N PF06970.6 EXF84703.1 - 0.079 12.7 0.2 0.21 11.3 0.1 1.7 1 0 0 1 1 1 0 Replication initiator protein A (RepA) N-terminus adh_short PF00106.20 EXF84704.1 - 6.4e-26 91.2 0.0 7.9e-26 90.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF84704.1 - 2.6e-14 53.5 0.0 3.3e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF84704.1 - 8e-07 28.8 0.1 1.2e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.13 EXF84704.1 - 0.026 14.1 0.1 0.047 13.3 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_31 PF13847.1 EXF84704.1 - 0.028 14.0 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EXF84704.1 - 0.035 13.6 0.0 0.054 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 2-Hacid_dh_C PF02826.14 EXF84704.1 - 0.043 12.9 0.1 0.083 12.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.3 EXF84704.1 - 0.084 12.6 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase SWIB PF02201.13 EXF84705.1 - 3.3e-13 49.1 0.0 7.4e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 SWIB/MDM2 domain Pkinase PF00069.20 EXF84706.1 - 1.4e-68 230.8 0.0 1.9e-68 230.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF84706.1 - 2.5e-35 121.8 0.0 1.9e-34 118.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF84706.1 - 2.7e-05 23.2 0.1 0.00084 18.3 0.0 2.5 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 EXF84706.1 - 0.00042 19.4 0.0 0.00075 18.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EXF84706.1 - 0.0042 16.8 0.1 0.012 15.3 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family MHYT PF03707.11 EXF84707.1 - 3.5e-06 27.0 21.4 0.00021 21.3 1.0 3.8 3 2 0 3 3 3 2 Bacterial signalling protein N terminal repeat WD40 PF00400.27 EXF84708.1 - 8.2e-40 133.3 18.9 3.6e-10 39.3 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat VCBS PF13517.1 EXF84708.1 - 0.39 11.1 2.8 3.8 7.9 0.0 3.0 3 0 0 3 3 3 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella WW PF00397.21 EXF84709.1 - 5.5e-07 29.3 0.2 1.5e-06 27.9 0.1 1.8 1 0 0 1 1 1 1 WW domain Pga1 PF10333.4 EXF84710.1 - 0.0018 17.9 0.1 0.0062 16.1 0.0 1.9 2 1 0 2 2 2 1 GPI-Mannosyltransferase II co-activator Tubulin PF00091.20 EXF84711.1 - 6.2e-69 232.1 0.0 8.8e-69 231.6 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EXF84711.1 - 1.5e-48 164.0 0.1 2.5e-48 163.2 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EXF84711.1 - 0.0028 17.1 0.0 0.0064 15.9 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain EF-hand_4 PF12763.2 EXF84712.1 - 1.2e-31 108.5 0.0 4.3e-12 45.6 0.0 3.4 3 0 0 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EXF84712.1 - 5.6e-07 29.6 0.0 0.0072 16.4 0.1 3.9 3 1 1 4 4 4 1 EF-hand domain pair UBA PF00627.26 EXF84712.1 - 6.1e-07 29.0 0.0 1.3e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain CENP-F_leu_zip PF10473.4 EXF84712.1 - 0.00017 21.4 31.8 0.0011 18.8 8.7 2.8 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EF-hand_1 PF00036.27 EXF84712.1 - 0.001 18.2 0.0 21 4.7 0.0 4.4 5 0 0 5 5 4 0 EF hand EF-hand_6 PF13405.1 EXF84712.1 - 0.0026 17.4 0.1 3.2 7.8 0.0 3.9 4 0 0 4 4 3 1 EF-hand domain IncA PF04156.9 EXF84712.1 - 0.0056 16.3 10.7 0.0056 16.3 7.4 3.0 2 1 1 3 3 2 2 IncA protein ATG16 PF08614.6 EXF84712.1 - 0.0081 15.9 33.7 0.035 13.9 14.7 2.6 1 1 1 2 2 2 2 Autophagy protein 16 (ATG16) Myosin_tail_1 PF01576.14 EXF84712.1 - 0.0084 13.8 29.0 0.021 12.5 20.0 1.6 1 1 0 1 1 1 1 Myosin tail DUF812 PF05667.6 EXF84712.1 - 0.01 14.3 20.5 0.02 13.3 14.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.7 EXF84712.1 - 0.011 15.5 35.8 0.15 11.7 13.7 2.3 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Macoilin PF09726.4 EXF84712.1 - 0.013 13.8 14.7 0.026 12.8 10.2 1.4 1 0 0 1 1 1 0 Transmembrane protein DUF3584 PF12128.3 EXF84712.1 - 0.026 11.8 26.8 0.037 11.3 18.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.6 EXF84712.1 - 0.05 12.2 28.5 0.24 9.9 6.0 2.2 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF869 PF05911.6 EXF84712.1 - 0.065 11.4 21.2 0.1 10.8 14.7 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) TMF_TATA_bd PF12325.3 EXF84712.1 - 0.073 12.8 26.9 0.2 11.3 3.1 3.3 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Reo_sigmaC PF04582.7 EXF84712.1 - 0.073 12.2 11.5 0.31 10.1 2.1 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein WEMBL PF05701.6 EXF84712.1 - 0.095 11.1 23.8 0.14 10.6 16.5 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light GAS PF13851.1 EXF84712.1 - 0.14 11.3 32.9 0.59 9.2 9.4 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Mnd1 PF03962.10 EXF84712.1 - 0.18 11.4 28.9 0.22 11.1 7.4 2.2 1 1 1 2 2 2 0 Mnd1 family CALCOCO1 PF07888.6 EXF84712.1 - 0.27 9.4 20.1 0.44 8.7 14.0 1.3 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like ADIP PF11559.3 EXF84712.1 - 0.27 11.1 41.9 0.035 14.0 9.6 3.5 2 1 2 4 4 3 0 Afadin- and alpha -actinin-Binding MscS_porin PF12795.2 EXF84712.1 - 0.3 10.3 41.1 2 7.6 28.5 2.0 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain AAA_27 PF13514.1 EXF84712.1 - 0.32 8.6 22.4 0.47 8.0 15.6 1.1 1 0 0 1 1 1 0 AAA domain MbeD_MobD PF04899.7 EXF84712.1 - 0.35 10.7 20.8 1.5 8.7 0.9 4.5 2 1 2 4 4 4 0 MbeD/MobD like Atg14 PF10186.4 EXF84712.1 - 0.61 8.9 31.8 0.1 11.5 9.1 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 bZIP_2 PF07716.10 EXF84712.1 - 0.88 9.4 10.0 2.5 7.9 3.5 3.0 2 0 0 2 2 2 0 Basic region leucine zipper DUF1664 PF07889.7 EXF84712.1 - 0.89 9.3 14.4 0.074 12.8 3.5 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) AAA_13 PF13166.1 EXF84712.1 - 1.2 7.5 24.5 1.8 6.9 17.0 1.2 1 0 0 1 1 1 0 AAA domain EzrA PF06160.7 EXF84712.1 - 1.2 7.2 24.2 0.2 9.8 13.1 1.8 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA Rab5-bind PF09311.6 EXF84712.1 - 1.9 8.3 39.2 0.34 10.7 13.4 3.3 2 1 1 3 3 3 0 Rabaptin-like protein Lebercilin PF15619.1 EXF84712.1 - 2.1 7.7 28.5 0.45 9.9 15.0 2.1 1 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Filament PF00038.16 EXF84712.1 - 2.6 7.4 29.3 90 2.3 20.3 2.1 1 1 0 1 1 1 0 Intermediate filament protein APG6 PF04111.7 EXF84712.1 - 6.3 5.7 33.7 2 7.4 12.5 2.2 1 1 1 2 2 2 0 Autophagy protein Apg6 DivIC PF04977.10 EXF84712.1 - 6.6 6.3 30.9 0.22 11.0 5.8 4.2 1 1 3 4 4 4 0 Septum formation initiator DUF4239 PF14023.1 EXF84712.1 - 6.9 5.9 6.2 5.7 6.2 3.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4239) DUF3450 PF11932.3 EXF84712.1 - 9.2 5.4 31.8 2.3 7.4 8.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Sec6 PF06046.8 EXF84713.1 - 6.1e-161 536.3 9.9 8.5e-161 535.8 6.9 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 Vps53_N PF04100.7 EXF84713.1 - 0.073 11.8 6.7 0.011 14.5 0.8 2.4 2 1 1 3 3 3 0 Vps53-like, N-terminal DUF755 PF05501.6 EXF84713.1 - 0.18 11.8 0.5 0.35 10.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DASH_Dam1 PF08653.5 EXF84713.1 - 0.19 11.5 2.5 4.7 7.0 0.2 4.2 5 0 0 5 5 5 0 DASH complex subunit Dam1 Pirin PF02678.11 EXF84714.1 - 7.1e-32 109.4 0.0 1.5e-31 108.3 0.0 1.6 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EXF84714.1 - 7.3e-26 90.2 0.0 1.3e-24 86.2 0.0 2.2 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EXF84714.1 - 9.1e-07 28.2 2.8 9e-05 21.8 0.5 2.8 2 0 0 2 2 2 2 Cupin domain Perilipin PF03036.11 EXF84715.1 - 0.00022 20.2 0.0 0.0003 19.7 0.0 1.2 1 0 0 1 1 1 1 Perilipin family DENN PF02141.16 EXF84718.1 - 6.8e-40 136.7 0.1 1.2e-39 135.9 0.0 1.4 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EXF84718.1 - 6.1e-06 26.1 0.2 3.2e-05 23.8 0.0 2.4 3 0 0 3 3 3 1 uDENN domain Elongin_A PF06881.6 EXF84718.1 - 0.0055 17.0 4.4 0.0055 17.0 3.0 2.4 2 0 0 2 2 2 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF4113 PF13438.1 EXF84718.1 - 0.012 15.2 0.4 1.3 8.6 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4113) PCRF PF03462.13 EXF84718.1 - 0.26 10.9 2.3 1.3 8.6 0.1 2.4 2 0 0 2 2 2 0 PCRF domain V_ATPase_I PF01496.14 EXF84718.1 - 1.4 6.6 6.8 2 6.1 4.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.6 EXF84718.1 - 7.3 5.1 11.2 12 4.3 7.8 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) DUF2570 PF10828.3 EXF84718.1 - 7.8 6.1 18.3 0.13 11.8 5.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2570) zf-HIT PF04438.11 EXF84719.1 - 5.1e-09 35.6 9.1 7.6e-09 35.0 6.3 1.3 1 0 0 1 1 1 1 HIT zinc finger Cpl-7 PF08230.6 EXF84719.1 - 0.12 12.0 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 Cpl-7 lysozyme C-terminal domain CFEM PF05730.6 EXF84720.1 - 1.9e-08 34.0 8.0 3.7e-08 33.0 5.6 1.4 1 0 0 1 1 1 1 CFEM domain Ribonuc_red_lgC PF02867.10 EXF84721.1 - 1.2e-222 740.2 0.0 1.7e-222 739.7 0.0 1.2 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EXF84721.1 - 2.8e-24 84.7 0.0 6.1e-23 80.4 0.0 2.6 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EXF84721.1 - 7.5e-16 58.3 0.2 3.3e-15 56.2 0.0 2.3 2 0 0 2 2 2 1 ATP cone domain Prok-E2_B PF14461.1 EXF84721.1 - 0.036 13.8 0.0 0.089 12.5 0.0 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family B TatD_DNase PF01026.16 EXF84722.1 - 3.7e-48 163.9 0.0 9.9e-48 162.5 0.0 1.6 1 1 0 1 1 1 1 TatD related DNase CENP-N PF05238.8 EXF84723.1 - 3.1e-125 418.3 0.0 3.5e-125 418.1 0.0 1.0 1 0 0 1 1 1 1 Kinetochore protein CHL4 like bZIP_2 PF07716.10 EXF84725.1 - 7.2e-12 44.9 12.1 1.1e-11 44.3 8.4 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EXF84725.1 - 4.4e-05 23.3 11.2 8.9e-05 22.3 7.8 1.5 1 0 0 1 1 1 1 bZIP transcription factor FTZ PF03867.9 EXF84725.1 - 0.058 12.6 3.6 0.038 13.2 0.9 1.8 2 0 0 2 2 2 0 Fushi tarazu (FTZ), N-terminal region TSC22 PF01166.13 EXF84725.1 - 0.079 12.9 0.8 0.19 11.7 0.6 1.7 1 1 0 1 1 1 0 TSC-22/dip/bun family XhlA PF10779.4 EXF84725.1 - 0.14 12.0 2.6 0.29 11.0 1.8 1.6 1 0 0 1 1 1 0 Haemolysin XhlA bZIP_Maf PF03131.12 EXF84725.1 - 0.32 11.3 8.6 0.25 11.6 4.8 1.7 1 1 0 1 1 1 0 bZIP Maf transcription factor DUF342 PF03961.8 EXF84725.1 - 1.1 7.6 6.4 1.4 7.2 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 EXF84725.1 - 2.6 7.6 8.2 3.3 7.2 5.7 1.1 1 0 0 1 1 1 0 IncA protein Med3 PF11593.3 EXF84726.1 - 0.48 9.6 9.7 0.64 9.2 6.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pneumo_att_G PF05539.6 EXF84726.1 - 4.2 6.6 10.3 5.1 6.3 7.2 1.3 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G Mif2_N PF15624.1 EXF84726.1 - 4.3 7.9 10.4 12 6.5 7.1 1.8 1 1 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal VWA_2 PF13519.1 EXF84727.1 - 1.1e-06 28.9 0.0 4.1e-06 26.9 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EXF84727.1 - 6.6e-06 25.9 0.0 0.087 12.5 0.0 2.2 2 0 0 2 2 2 2 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EXF84727.1 - 0.0003 20.6 0.0 0.00045 20.0 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus Pol_alpha_B_N PF08418.5 EXF84727.1 - 0.089 12.3 5.6 0.14 11.7 3.8 1.3 1 1 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal DUF4597 PF15366.1 EXF84727.1 - 1.9 8.1 8.7 0.31 10.6 2.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4597) Aminotran_1_2 PF00155.16 EXF84728.1 - 2.7e-34 118.7 0.0 3.1e-34 118.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2309 PF10070.4 EXF84730.1 - 0.045 11.8 2.7 0.062 11.4 1.8 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) DUF342 PF03961.8 EXF84730.1 - 0.093 11.1 2.5 0.14 10.5 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) FANCI_S3 PF14677.1 EXF84730.1 - 0.11 11.8 0.4 0.19 11.0 0.3 1.2 1 0 0 1 1 1 0 FANCI solenoid 3 CDC37_N PF03234.9 EXF84730.1 - 0.15 12.4 5.5 0.36 11.1 3.8 1.6 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding DUF1664 PF07889.7 EXF84730.1 - 0.26 11.0 1.1 0.48 10.2 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) RRM_1 PF00076.17 EXF84731.1 - 1.1e-43 146.7 0.7 7e-20 70.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF84731.1 - 3.2e-33 113.5 0.1 3e-16 59.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EXF84731.1 - 3.2e-30 104.2 0.2 6.9e-30 103.1 0.1 1.6 1 0 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_5 PF13893.1 EXF84731.1 - 9.4e-22 76.6 0.0 5.9e-08 32.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EXF84731.1 - 0.00076 19.3 0.2 0.032 14.0 0.0 2.9 2 1 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 EXF84731.1 - 0.056 13.2 0.0 5.2 6.9 0.0 2.6 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Cyt-b5 PF00173.23 EXF84732.1 - 4.3e-19 68.0 0.3 2e-18 65.9 0.1 2.1 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.8 EXF84732.1 - 2.6e-06 27.8 23.7 2.6e-06 27.8 16.4 1.7 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.8 EXF84732.1 - 0.057 13.4 0.1 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region Het-C PF07217.6 EXF84733.1 - 5.5e-289 959.5 0.0 6.4e-289 959.3 0.0 1.0 1 0 0 1 1 1 1 Heterokaryon incompatibility protein Het-C PP2C PF00481.16 EXF84734.1 - 1.6e-38 132.5 0.0 9.1e-33 113.7 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EXF84734.1 - 1.7e-05 24.3 0.0 3.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C BTB PF00651.26 EXF84735.1 - 0.026 14.5 1.0 5 7.1 0.0 2.9 3 0 0 3 3 3 0 BTB/POZ domain FTR1 PF03239.9 EXF84736.1 - 4.4e-81 272.1 9.7 5.6e-81 271.8 6.7 1.0 1 0 0 1 1 1 1 Iron permease FTR1 family DUF4231 PF14015.1 EXF84736.1 - 3.1 7.8 8.1 0.2 11.6 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) SUR7 PF06687.7 EXF84736.1 - 8.8 5.8 12.0 0.29 10.6 1.4 2.8 3 0 0 3 3 3 0 SUR7/PalI family Cu-oxidase PF00394.17 EXF84737.1 - 4.6e-42 143.6 1.2 9.5e-38 129.5 0.1 2.8 2 0 0 2 2 2 2 Multicopper oxidase Cu-oxidase_2 PF07731.9 EXF84737.1 - 1.8e-41 140.9 7.2 1.4e-38 131.5 0.4 3.0 3 1 0 3 3 3 2 Multicopper oxidase Cu-oxidase_3 PF07732.10 EXF84737.1 - 1.3e-40 137.8 6.6 1.4e-37 128.0 1.8 3.9 4 0 0 4 4 4 2 Multicopper oxidase Cupredoxin_1 PF13473.1 EXF84737.1 - 0.003 17.4 0.0 28 4.6 0.0 3.6 3 0 0 3 3 3 1 Cupredoxin-like domain CDP-OH_P_transf PF01066.16 EXF84738.1 - 3.8e-18 65.6 4.3 3.8e-18 65.6 3.0 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase OMPdecase PF00215.19 EXF84739.1 - 2.4e-99 331.3 0.0 2.8e-99 331.1 0.0 1.0 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Ank_2 PF12796.2 EXF84740.1 - 1.8e-35 121.1 0.5 2.3e-11 43.8 0.1 4.6 4 1 1 5 5 5 4 Ankyrin repeats (3 copies) Ank PF00023.25 EXF84740.1 - 8.8e-27 91.5 10.1 1.2e-05 24.8 0.0 8.7 10 0 0 10 10 10 4 Ankyrin repeat Ank_5 PF13857.1 EXF84740.1 - 1.1e-20 73.1 5.7 0.0018 18.4 0.0 7.1 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF84740.1 - 5.4e-19 66.4 3.6 0.00076 19.4 0.0 7.4 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.1 EXF84740.1 - 4.3e-17 62.1 4.1 4.3e-07 30.2 0.0 5.7 3 2 5 8 8 7 5 Ankyrin repeats (many copies) NACHT PF05729.7 EXF84740.1 - 2.6e-10 40.2 0.2 2.8e-09 36.8 0.1 2.4 1 1 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EXF84740.1 - 6.8e-09 35.9 0.1 6.5e-08 32.7 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EXF84740.1 - 1.3e-05 25.3 0.2 9.2e-05 22.5 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA PF00004.24 EXF84740.1 - 0.00074 19.7 0.1 0.0081 16.3 0.1 2.5 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.17 EXF84740.1 - 0.0014 17.5 0.0 0.0028 16.5 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain DUF2075 PF09848.4 EXF84740.1 - 0.002 17.1 0.0 0.0033 16.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EXF84740.1 - 0.002 17.8 0.0 0.0075 16.0 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EXF84740.1 - 0.0052 16.3 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 EXF84740.1 - 0.011 14.7 0.2 0.87 8.5 0.0 2.3 1 1 0 2 2 2 0 KAP family P-loop domain AAA_14 PF13173.1 EXF84740.1 - 0.017 14.9 0.1 0.42 10.5 0.0 2.8 2 1 0 2 2 2 0 AAA domain Arch_ATPase PF01637.13 EXF84740.1 - 0.023 14.3 0.0 0.051 13.2 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase Mg_chelatase PF01078.16 EXF84740.1 - 0.099 11.7 0.0 0.2 10.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.7 EXF84740.1 - 0.14 11.2 0.0 0.3 10.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Mus7 PF09462.5 EXF84742.1 - 1.1e-124 417.5 3.7 1.5e-124 417.1 2.6 1.2 1 0 0 1 1 1 1 Mus7/MMS22 family Activator-TraM PF11657.3 EXF84742.1 - 0.14 11.6 2.8 1.4 8.4 0.2 2.4 2 0 0 2 2 2 0 Transcriptional activator TraM AAA PF00004.24 EXF84743.1 - 8.3e-39 132.8 0.2 1.9e-37 128.4 0.0 2.9 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EXF84743.1 - 4.4e-08 33.3 2.3 0.0016 18.4 0.0 4.7 3 1 1 4 4 4 1 AAA ATPase domain AAA_22 PF13401.1 EXF84743.1 - 9.8e-07 28.9 0.5 0.015 15.4 0.0 3.9 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.7 EXF84743.1 - 1.2e-05 24.5 0.0 2.5e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EXF84743.1 - 0.00012 22.8 0.0 0.00062 20.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EXF84743.1 - 0.00081 19.2 0.0 0.0053 16.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EXF84743.1 - 0.001 18.5 0.0 0.0024 17.3 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.1 EXF84743.1 - 0.0023 17.8 0.2 0.014 15.3 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EXF84743.1 - 0.0023 17.6 0.1 0.009 15.7 0.0 2.0 2 0 0 2 2 1 1 Part of AAA domain AAA_18 PF13238.1 EXF84743.1 - 0.0094 16.2 0.0 0.047 13.9 0.0 2.2 3 0 0 3 3 1 1 AAA domain AAA_5 PF07728.9 EXF84743.1 - 0.0099 15.6 0.1 0.028 14.1 0.1 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EXF84743.1 - 0.014 15.1 0.1 6.7 6.3 0.0 2.7 2 1 1 3 3 3 0 Archaeal ATPase AAA_25 PF13481.1 EXF84743.1 - 0.016 14.6 0.7 0.56 9.5 0.1 3.3 2 1 1 3 3 3 0 AAA domain RNA_helicase PF00910.17 EXF84743.1 - 0.021 14.9 0.0 0.072 13.2 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 EXF84743.1 - 0.029 14.3 0.1 0.32 10.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EXF84743.1 - 0.035 13.2 0.0 0.074 12.1 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.7 EXF84743.1 - 0.036 13.7 0.3 2.1 7.9 0.0 2.8 2 0 0 2 2 2 0 NACHT domain TIP49 PF06068.8 EXF84743.1 - 0.051 12.2 0.0 0.088 11.5 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus Sigma54_activ_2 PF14532.1 EXF84743.1 - 0.075 13.0 0.0 0.27 11.2 0.0 1.9 2 0 0 2 2 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 EXF84743.1 - 0.082 12.4 0.4 0.2 11.1 0.3 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EXF84743.1 - 0.17 10.8 1.0 0.57 9.0 0.1 2.2 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_10 PF12846.2 EXF84743.1 - 0.2 11.0 1.5 9.7 5.5 0.1 2.8 2 1 1 3 3 3 0 AAA-like domain TFIIH_BTF_p62_N PF08567.6 EXF84744.1 - 8.6e-24 83.0 0.0 2.1e-23 81.7 0.0 1.6 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.12 EXF84744.1 - 3.2e-22 78.0 2.0 3.9e-12 45.7 0.0 3.2 3 0 0 3 3 3 2 BSD domain LsmAD PF06741.8 EXF84746.1 - 5.7e-21 74.3 1.4 5.7e-21 74.3 1.0 2.4 2 0 0 2 2 2 1 LsmAD domain Peptidase_M16 PF00675.15 EXF84747.1 - 5.6e-17 61.8 0.1 1e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EXF84747.1 - 5e-13 49.1 0.0 1.5e-12 47.5 0.0 1.8 2 0 0 2 2 2 1 Peptidase M16 inactive domain bact-PGI_C PF10432.4 EXF84747.1 - 0.03 14.0 0.4 0.055 13.1 0.3 1.4 1 0 0 1 1 1 0 Bacterial phospho-glucose isomerase C-terminal region RNA_pol_Rpc82 PF05645.8 EXF84748.1 - 7.1e-48 163.3 0.0 7.7e-47 159.9 0.0 2.4 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 HTH_9 PF08221.6 EXF84748.1 - 5.3e-14 51.8 0.3 1.6e-12 47.1 0.1 2.8 2 0 0 2 2 2 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.12 EXF84748.1 - 1.8e-06 27.4 0.1 0.0033 16.8 0.0 3.4 3 1 0 3 3 3 2 TFIIE alpha subunit Mito_carr PF00153.22 EXF84749.1 - 4.9e-30 103.0 0.6 1.4e-15 56.7 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Amino_oxidase PF01593.19 EXF84750.1 - 8e-30 104.2 2.2 3.2e-26 92.4 0.1 2.5 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.19 EXF84750.1 - 1.9e-08 33.6 0.0 6.6e-06 25.2 0.0 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF84750.1 - 6.4e-06 25.2 0.2 2.5e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.1 EXF84750.1 - 9.2e-06 25.5 0.7 3.9e-05 23.5 0.1 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF84750.1 - 2.1e-05 24.4 0.0 3.7e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF84750.1 - 6.4e-05 22.0 0.7 0.016 14.1 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein FAD_oxidored PF12831.2 EXF84750.1 - 0.0002 20.6 0.4 0.019 14.0 0.2 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EXF84750.1 - 0.00041 18.9 0.0 0.00065 18.2 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 EXF84750.1 - 0.0017 17.4 0.0 0.003 16.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EXF84750.1 - 0.0023 17.0 0.1 0.0038 16.3 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EXF84750.1 - 0.0036 17.6 0.2 0.041 14.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF84750.1 - 0.0089 14.9 0.1 0.018 13.9 0.0 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A Sugar_tr PF00083.19 EXF84751.1 - 4.3e-101 338.7 18.6 5.1e-101 338.4 12.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF84751.1 - 6.1e-26 90.9 52.6 1.8e-24 86.1 18.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EXF84751.1 - 0.0019 17.9 0.2 0.0088 15.8 0.1 2.2 2 0 0 2 2 2 1 MFS_1 like family Tmemb_18A PF09771.4 EXF84751.1 - 0.68 9.9 2.7 22 5.0 0.1 3.3 2 1 1 3 3 3 0 Transmembrane protein 188 PITH PF06201.8 EXF84753.1 - 7.4e-48 162.1 0.0 8.8e-48 161.9 0.0 1.1 1 0 0 1 1 1 1 PITH domain Rrn6 PF10214.4 EXF84754.1 - 1.9e-59 201.5 22.8 1.2e-57 195.6 0.0 3.1 2 1 0 2 2 2 1 RNA polymerase I-specific transcription-initiation factor MOZART1 PF12554.3 EXF84755.1 - 2.7e-27 93.9 0.8 3.3e-27 93.6 0.6 1.1 1 0 0 1 1 1 1 Mitotic-spindle organizing gamma-tubulin ring associated zinc_ribbon_6 PF14599.1 EXF84756.1 - 1.7e-25 88.5 0.0 1.7e-25 88.5 0.0 4.1 3 1 0 3 3 3 1 Zinc-ribbon zf-CHY PF05495.7 EXF84756.1 - 2.2e-17 62.9 19.6 2.2e-17 62.9 13.6 4.3 3 1 1 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.1 EXF84756.1 - 2.3e-08 33.7 9.2 2.3e-08 33.7 6.4 5.5 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EXF84756.1 - 5.9e-07 29.4 7.4 5.9e-07 29.4 5.2 5.7 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EXF84756.1 - 1e-06 28.2 7.6 1e-06 28.2 5.3 5.9 2 1 3 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EXF84756.1 - 1.9e-05 24.2 7.6 1.9e-05 24.2 5.3 7.1 3 2 1 4 4 4 1 zinc-RING finger domain Myc_N PF01056.13 EXF84756.1 - 0.064 12.4 3.9 0.05 12.7 0.5 2.0 2 0 0 2 2 2 0 Myc amino-terminal region PMT PF02366.13 EXF84757.1 - 9.9e-80 267.4 12.8 9.9e-80 267.4 8.9 2.4 2 1 0 2 2 2 1 Dolichyl-phosphate-mannose-protein mannosyltransferase MIR PF02815.14 EXF84757.1 - 1.5e-37 128.9 0.2 2.1e-37 128.4 0.1 1.2 1 0 0 1 1 1 1 MIR domain Ras PF00071.17 EXF84758.1 - 3.2e-50 169.6 0.0 3.3e-39 133.8 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EXF84758.1 - 2e-16 60.5 0.0 1.5e-15 57.7 0.0 2.1 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EXF84758.1 - 1.9e-10 40.2 0.0 6e-10 38.6 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EXF84758.1 - 2.4e-07 30.3 0.0 2.5e-06 27.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EXF84758.1 - 9.5e-07 28.1 0.0 2.2e-06 26.9 0.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EXF84758.1 - 0.00013 21.9 0.0 0.00028 20.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EXF84758.1 - 0.031 14.4 0.0 0.67 10.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EXF84758.1 - 0.048 13.0 0.1 4.6 6.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.4 EXF84758.1 - 0.098 12.1 0.1 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EXF84758.1 - 0.11 12.4 0.1 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Choline_transpo PF04515.7 EXF84759.1 - 2.5e-10 39.6 22.4 2.5e-10 39.6 15.6 3.2 3 1 0 3 3 3 2 Plasma-membrane choline transporter WW PF00397.21 EXF84760.1 - 1.5e-08 34.3 3.9 2.9e-08 33.4 2.7 1.5 1 0 0 1 1 1 1 WW domain Spore_YtfJ PF09579.5 EXF84761.1 - 0.84 9.5 14.7 0.7 9.7 0.2 2.1 2 0 0 2 2 2 0 Sporulation protein YtfJ (Spore_YtfJ) M_domain PF12938.2 EXF84761.1 - 5.8 6.6 7.4 5.8 6.6 5.1 1.0 1 0 0 1 1 1 0 M domain of GW182 Pico_P1A PF02226.11 EXF84762.1 - 0.093 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Picornavirus coat protein (VP4) 2OG-FeII_Oxy PF03171.15 EXF84763.1 - 4.2e-14 52.6 0.0 7.5e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EXF84763.1 - 3.4e-08 34.0 0.0 5.8e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal adh_short PF00106.20 EXF84764.1 - 1.4e-13 51.0 1.1 9.7e-12 45.1 0.8 2.6 1 1 0 1 1 1 1 short chain dehydrogenase AIRC PF00731.15 EXF84764.1 - 0.0024 17.1 1.9 0.011 14.9 0.5 2.1 2 0 0 2 2 2 1 AIR carboxylase Eno-Rase_NADH_b PF12242.3 EXF84764.1 - 0.0052 16.5 0.1 0.012 15.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase KR PF08659.5 EXF84764.1 - 0.014 15.0 1.6 0.031 13.9 0.5 2.2 1 1 1 2 2 2 0 KR domain NAD_binding_10 PF13460.1 EXF84764.1 - 0.023 14.6 0.0 0.054 13.5 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding adh_short_C2 PF13561.1 EXF84764.1 - 0.26 11.0 1.6 4.3 7.0 0.2 2.1 1 1 0 2 2 2 0 Enoyl-(Acyl carrier protein) reductase Terpene_synth_C PF03936.11 EXF84765.1 - 6.6e-22 78.0 0.4 8.7e-22 77.6 0.3 1.1 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain PSD2 PF07624.6 EXF84765.1 - 0.079 12.6 0.0 0.22 11.2 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1585) Cys_Met_Meta_PP PF01053.15 EXF84766.1 - 1.2e-124 415.5 0.0 1e-122 409.2 0.0 2.0 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.14 EXF84766.1 - 1.8e-08 33.5 0.0 1.8e-07 30.2 0.0 2.4 2 1 1 3 3 3 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EXF84766.1 - 6.9e-07 28.5 0.0 1.1e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EXF84766.1 - 0.0016 17.5 0.8 0.0032 16.5 0.5 1.5 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family GDC-P PF02347.11 EXF84766.1 - 0.0017 17.0 0.0 0.0026 16.4 0.0 1.2 1 0 0 1 1 1 1 Glycine cleavage system P-protein Met_gamma_lyase PF06838.6 EXF84766.1 - 0.0067 14.7 0.0 0.0097 14.2 0.0 1.2 1 0 0 1 1 1 1 Methionine gamma-lyase TNV_CP PF03898.8 EXF84766.1 - 0.074 12.1 0.5 0.14 11.1 0.3 1.4 1 0 0 1 1 1 0 Satellite tobacco necrosis virus coat protein p450 PF00067.17 EXF84767.1 - 1.5e-39 135.8 0.1 2.4e-39 135.1 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EXF84769.1 - 1.1e-28 100.2 0.1 1.5e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF84769.1 - 1.3e-27 97.1 0.0 1.5e-27 96.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF84769.1 - 2.3e-09 37.1 0.0 3.1e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1537 PF07005.6 EXF84769.1 - 0.012 15.2 0.3 0.019 14.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF1537 ETF PF01012.16 EXF84769.1 - 0.1 12.3 1.6 0.17 11.5 0.5 1.7 2 1 0 2 2 2 0 Electron transfer flavoprotein domain PA PF02225.17 EXF84769.1 - 0.2 11.3 1.0 0.38 10.4 0.7 1.4 1 0 0 1 1 1 0 PA domain DUF4538 PF15061.1 EXF84770.1 - 0.1 11.9 0.9 0.21 10.9 0.4 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4538) TRAPPC10 PF12584.3 EXF84771.1 - 1.1e-20 73.6 0.0 1.9e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 EXF84771.1 - 0.036 13.5 0.1 0.058 12.8 0.1 1.2 1 0 0 1 1 1 0 Foie gras liver health family 1 IF-2B PF01008.12 EXF84772.1 - 6.2e-78 261.6 2.9 7.4e-78 261.3 2.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family ACOX PF01756.14 EXF84772.1 - 0.086 12.2 0.1 6.2 6.1 0.0 2.2 2 0 0 2 2 2 0 Acyl-CoA oxidase Peptidase_M20 PF01546.23 EXF84773.1 - 6.9e-20 71.3 0.1 1e-19 70.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EXF84773.1 - 7.2e-19 67.5 0.1 1.4e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EXF84773.1 - 0.017 14.8 0.0 0.026 14.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M28 Pkinase PF00069.20 EXF84774.1 - 3.3e-66 223.1 0.0 5.2e-66 222.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF84774.1 - 5e-40 137.2 0.0 7e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF84774.1 - 1.8e-10 40.2 0.0 1.5e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EXF84774.1 - 5.5e-05 23.0 6.7 0.039 13.6 0.1 3.8 2 2 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EXF84774.1 - 0.007 15.4 0.0 0.015 14.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EXF84774.1 - 0.078 11.7 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Prenyltrans PF00432.16 EXF84775.1 - 4.4e-32 109.3 8.8 5.1e-06 25.9 0.1 5.9 5 1 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EXF84775.1 - 4.8e-18 65.6 0.0 1.7e-08 34.8 0.0 4.2 2 1 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EXF84775.1 - 0.029 14.3 0.1 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 Prenyltransferase-like Ilm1 PF10311.4 EXF84776.1 - 1e-55 187.7 0.1 1.2e-55 187.5 0.1 1.0 1 0 0 1 1 1 1 Increased loss of mitochondrial DNA protein 1 NatB_MDM20 PF09797.4 EXF84777.1 - 8.3e-54 182.6 0.1 2.1e-53 181.3 0.0 1.7 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit zf-RanBP PF00641.13 EXF84777.1 - 0.96 8.6 8.3 2.4 7.3 5.8 1.7 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others CHCH PF06747.8 EXF84778.1 - 2.4e-06 27.3 2.2 3.7e-06 26.7 1.5 1.4 1 0 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 EXF84778.1 - 4.8e-05 23.4 1.6 7e-05 22.9 1.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1903) COX6B PF02297.12 EXF84778.1 - 0.00038 20.4 4.3 0.0007 19.5 2.6 1.6 1 1 1 2 2 2 1 Cytochrome oxidase c subunit VIb Cmc1 PF08583.5 EXF84778.1 - 0.11 12.3 2.7 3.1 7.6 0.1 2.3 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like UPF0203 PF05254.7 EXF84778.1 - 1.2 9.0 4.7 14 5.5 3.0 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) Glyco_hydro_61 PF03443.9 EXF84779.1 - 1.1e-51 175.7 1.8 1.7e-51 175.0 1.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 Spiralin PF05215.8 EXF84779.1 - 0.018 14.1 0.0 0.018 14.1 0.0 1.6 2 0 0 2 2 2 0 Spiralin SOBP PF15279.1 EXF84779.1 - 0.17 12.2 2.4 0.24 11.7 1.7 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Med3 PF11593.3 EXF84779.1 - 2.2 7.4 23.9 3.2 6.8 16.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal CDK2AP PF09806.4 EXF84779.1 - 3.9 7.6 11.5 7 6.8 8.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Brix PF04427.13 EXF84780.1 - 0.21 11.2 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Brix domain LigB PF02900.13 EXF84781.1 - 5.1e-42 143.7 0.0 9e-42 142.9 0.0 1.3 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Amidohydro_4 PF13147.1 EXF84781.1 - 1.2e-11 45.1 1.0 3.7e-07 30.4 0.0 3.9 3 1 0 3 3 3 3 Amidohydrolase Amidohydro_5 PF13594.1 EXF84781.1 - 1.2e-07 31.3 0.9 1.4e-06 27.9 0.1 2.7 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_1 PF01979.15 EXF84781.1 - 1.4e-06 28.2 0.1 3.4e-05 23.6 0.0 2.6 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.6 EXF84781.1 - 0.00034 19.9 0.3 0.00085 18.6 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase family DUF3445 PF11927.3 EXF84782.1 - 6.1e-71 238.7 0.0 7.7e-71 238.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3445) Herpes_BLLF1 PF05109.8 EXF84783.1 - 0.98 7.3 29.7 1.3 6.8 20.6 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) DUF605 PF04652.11 EXF84783.1 - 4 6.7 18.9 6 6.1 13.1 1.2 1 0 0 1 1 1 0 Vta1 like adh_short PF00106.20 EXF84784.1 - 3.7e-13 49.7 0.0 5.3e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF84784.1 - 1.2e-05 25.0 0.0 2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EXF84784.1 - 4.5e-05 23.5 0.2 0.0004 20.4 0.1 2.3 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF84784.1 - 0.00014 21.3 0.0 0.00037 20.0 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EXF84784.1 - 0.0029 17.3 0.0 0.0041 16.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.14 EXF84784.1 - 0.007 15.4 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain SWIB PF02201.13 EXF84785.1 - 4.8e-28 96.6 0.7 3e-27 94.0 0.2 2.1 2 0 0 2 2 2 1 SWIB/MDM2 domain DEK_C PF08766.6 EXF84785.1 - 1.6e-14 53.3 1.2 6.5e-14 51.4 0.5 2.0 2 0 0 2 2 2 1 DEK C terminal domain U79_P34 PF03064.11 EXF84785.1 - 0.34 10.4 7.1 0.58 9.6 4.9 1.4 1 0 0 1 1 1 0 HSV U79 / HCMV P34 XRCC4 PF06632.7 EXF84785.1 - 1.4 7.7 7.5 2.8 6.6 5.2 1.5 1 1 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 Zn_clus PF00172.13 EXF84786.1 - 1e-08 34.9 13.1 1.6e-08 34.3 9.1 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ribosomal_S10 PF00338.17 EXF84787.1 - 0.026 14.3 0.0 0.041 13.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e UAF_Rrn10 PF05234.6 EXF84788.1 - 0.0056 16.7 0.0 0.035 14.1 0.0 2.0 1 1 0 1 1 1 1 UAF complex subunit Rrn10 WD40 PF00400.27 EXF84789.1 - 1.4e-30 104.0 10.1 3.5e-08 33.0 0.2 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 EXF84789.1 - 0.0035 15.5 2.4 0.45 8.6 0.0 3.7 3 1 1 4 4 4 2 Nucleoporin Nup120/160 RNB PF00773.14 EXF84789.1 - 0.017 14.4 0.1 0.024 13.9 0.1 1.2 1 0 0 1 1 1 0 RNB domain TSNR_N PF04705.7 EXF84789.1 - 0.13 12.0 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Thiostrepton-resistance methylase, N terminus MARVEL PF01284.18 EXF84791.1 - 4.2e-20 72.0 12.3 5.1e-20 71.7 8.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain DUF2976 PF11190.3 EXF84791.1 - 0.04 13.4 3.1 0.089 12.3 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Choline_transpo PF04515.7 EXF84791.1 - 0.092 11.4 4.7 0.16 10.6 1.7 2.0 2 0 0 2 2 2 0 Plasma-membrane choline transporter DUF588 PF04535.7 EXF84791.1 - 0.11 12.0 2.8 0.15 11.5 0.9 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF588) ABC2_membrane_5 PF13346.1 EXF84791.1 - 0.12 11.6 5.9 0.18 11.1 4.1 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF308 PF03729.8 EXF84791.1 - 1.1 9.2 13.9 0.25 11.3 1.5 3.1 3 0 0 3 3 3 0 Short repeat of unknown function (DUF308) DUF4149 PF13664.1 EXF84791.1 - 2.7 8.1 7.0 4.7 7.3 1.0 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) Acyl-CoA_dh_1 PF00441.19 EXF84792.1 - 2.4e-16 60.1 0.1 1.7e-15 57.4 0.1 2.2 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EXF84792.1 - 7.4e-05 22.1 0.5 0.0011 18.3 0.5 2.7 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EXF84792.1 - 0.001 19.3 0.1 3.4 7.9 0.0 3.0 3 0 0 3 3 3 2 Acyl-CoA dehydrogenase, C-terminal domain Tweety PF04906.8 EXF84793.1 - 0.065 11.6 2.1 0.092 11.1 1.5 1.2 1 0 0 1 1 1 0 Tweety SNF2_N PF00176.18 EXF84794.1 - 2.1e-56 190.9 0.1 3e-56 190.4 0.1 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain VIGSSK PF14773.1 EXF84794.1 - 3.9e-25 87.5 1.8 1.3e-24 85.8 1.2 2.0 1 0 0 1 1 1 1 Helicase-associated putative binding domain, C-terminal Helicase_C PF00271.26 EXF84794.1 - 6.1e-15 54.8 0.0 1.1e-13 50.8 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 EXF84794.1 - 2.2e-05 23.9 0.0 5.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase HDA2-3 PF11496.3 EXF84794.1 - 0.016 14.0 0.0 0.04 12.7 0.0 1.6 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 Glyco_transf_8 PF01501.15 EXF84795.1 - 8.9e-24 84.1 0.0 1.2e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 ATG2_CAD PF13329.1 EXF84796.1 - 5.5e-52 175.4 1.0 5.5e-52 175.4 0.7 2.2 3 0 0 3 3 3 1 Autophagy-related protein 2 CAD motif ATG_C PF09333.6 EXF84796.1 - 9.2e-31 105.9 0.0 3.8e-30 103.9 0.1 2.1 2 0 0 2 2 2 1 ATG C terminal domain Chorein_N PF12624.2 EXF84796.1 - 0.00068 19.1 0.2 0.0046 16.4 0.0 2.3 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Amino_oxidase PF01593.19 EXF84797.1 - 1e-36 126.9 0.5 1.8e-34 119.5 0.3 2.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EXF84797.1 - 3.3e-13 49.4 0.0 7.1e-13 48.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EXF84797.1 - 1.1e-05 25.7 0.2 2.4e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF84797.1 - 0.00011 21.2 0.3 0.00026 19.9 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EXF84797.1 - 0.00014 22.0 0.2 0.00032 20.8 0.1 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF84797.1 - 0.00043 20.0 0.1 0.28 10.9 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 EXF84797.1 - 0.00082 18.3 0.1 0.0016 17.3 0.1 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF84797.1 - 0.0011 18.8 0.1 0.0028 17.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF84797.1 - 0.0012 17.3 0.1 0.004 15.6 0.1 1.7 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EXF84797.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family FAD_binding_3 PF01494.14 EXF84797.1 - 0.016 14.3 1.1 0.026 13.5 0.8 1.2 1 0 0 1 1 1 0 FAD binding domain 3HCDH_N PF02737.13 EXF84797.1 - 0.03 13.9 0.8 0.048 13.3 0.1 1.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.2 EXF84797.1 - 0.11 11.4 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF84797.1 - 0.21 10.4 0.3 0.31 9.8 0.2 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.17 EXF84797.1 - 0.29 9.9 1.1 0.35 9.6 0.1 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Acyl-CoA_dh_1 PF00441.19 EXF84799.1 - 2.5e-32 112.0 0.8 3.5e-32 111.5 0.5 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cyt-b5 PF00173.23 EXF84799.1 - 1e-18 66.8 0.1 2.6e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Acyl-CoA_dh_M PF02770.14 EXF84799.1 - 6.9e-18 63.9 0.4 1.3e-17 63.0 0.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EXF84799.1 - 1.7e-11 44.6 0.1 8.9e-11 42.3 0.0 2.1 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EXF84799.1 - 0.0054 16.9 0.0 0.01 16.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EXF84799.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal zf-CCHC PF00098.18 EXF84800.1 - 1.2e-24 84.9 25.9 5.8e-09 35.4 2.2 3.9 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_4 PF14392.1 EXF84800.1 - 8.8e-08 31.6 13.4 0.0025 17.4 0.3 3.3 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_2 PF13696.1 EXF84800.1 - 1e-05 24.8 12.7 0.1 12.1 1.1 3.4 1 1 2 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.1 EXF84800.1 - 3.6e-05 23.4 15.0 0.086 12.5 0.3 3.4 1 1 2 3 3 3 3 Zinc knuckle zf-CCHC_6 PF15288.1 EXF84800.1 - 0.00058 19.4 20.4 0.053 13.1 1.0 3.3 2 1 1 3 3 3 3 Zinc knuckle RMF PF04957.7 EXF84800.1 - 0.34 10.6 6.0 0.44 10.2 0.9 2.6 1 1 2 3 3 3 0 Ribosome modulation factor IBR PF01485.16 EXF84800.1 - 1.4 8.8 16.0 0.96 9.3 1.9 3.2 1 1 2 3 3 3 0 IBR domain Toxin_44 PF15523.1 EXF84800.1 - 4.9 7.0 10.0 3.9 7.4 0.6 3.2 2 1 1 3 3 3 0 Putative toxin 44 SAE2 PF08573.5 EXF84802.1 - 2e-25 89.2 0.0 2e-25 89.2 0.0 2.9 4 0 0 4 4 4 1 DNA repair protein endonuclease SAE2/CtIP C-terminus KIAA1430 PF13879.1 EXF84802.1 - 0.22 11.9 5.3 0.16 12.3 1.5 2.4 2 1 0 2 2 2 0 KIAA1430 homologue HALZ PF02183.13 EXF84802.1 - 4.8 6.9 7.9 19 5.0 0.7 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper Cauli_AT PF03233.8 EXF84802.1 - 6.5 6.4 5.8 1.6 8.4 0.9 2.0 2 0 0 2 2 2 0 Aphid transmission protein UCH PF00443.24 EXF84803.1 - 1.8e-49 168.2 0.0 3.4e-49 167.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EXF84803.1 - 5.5e-15 55.5 0.0 1.4e-14 54.2 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HNOBA PF07701.9 EXF84803.1 - 0.028 13.6 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Heme NO binding associated DUF952 PF06108.7 EXF84804.1 - 2.6e-22 78.4 0.0 3.2e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF952) PQQ PF01011.16 EXF84804.1 - 0.1 12.1 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat Pkinase PF00069.20 EXF84805.1 - 4.3e-69 232.5 0.0 6.9e-69 231.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF84805.1 - 3.6e-49 167.1 0.0 5.9e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF84805.1 - 0.00067 18.7 0.0 0.0018 17.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.9 EXF84805.1 - 0.031 13.3 0.0 0.064 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mur_ligase_M PF08245.7 EXF84807.1 - 6.3e-05 23.0 1.8 0.00045 20.3 1.2 2.3 1 1 0 1 1 1 1 Mur ligase middle domain Gla PF00594.15 EXF84807.1 - 0.19 11.4 0.0 0.35 10.5 0.0 1.4 1 0 0 1 1 1 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain Viral_DNA_bp PF00747.12 EXF84808.1 - 0.012 12.8 0.0 0.015 12.5 0.0 1.0 1 0 0 1 1 1 0 ssDNA binding protein Abhydrolase_5 PF12695.2 EXF84810.1 - 4.8e-07 29.6 0.0 9.3e-07 28.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF84810.1 - 1.3e-05 25.2 0.4 2e-05 24.5 0.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF84810.1 - 0.0018 17.5 0.0 0.084 12.0 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Serglycin PF04360.7 EXF84810.1 - 0.0085 15.8 0.1 0.016 14.9 0.1 1.4 1 0 0 1 1 1 1 Serglycin Abhydrolase_2 PF02230.11 EXF84810.1 - 0.011 15.1 0.0 0.15 11.5 0.0 2.1 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.13 EXF84810.1 - 0.035 13.4 0.0 0.42 9.8 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family SR-25 PF10500.4 EXF84810.1 - 0.58 9.5 6.8 0.8 9.1 4.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein ICE2 PF08426.5 EXF84811.1 - 7.6e-139 462.8 11.6 8.8e-139 462.6 8.0 1.0 1 0 0 1 1 1 1 ICE2 FA_desaturase PF00487.19 EXF84813.1 - 1.8e-29 102.9 17.7 2.8e-29 102.3 12.3 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EXF84813.1 - 1.2e-19 69.2 0.3 2.3e-19 68.3 0.2 1.5 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Motile_Sperm PF00635.21 EXF84814.1 - 5.7e-25 87.0 0.6 2e-24 85.3 0.5 1.9 1 1 1 2 2 2 1 MSP (Major sperm protein) domain FixG_C PF11614.3 EXF84814.1 - 0.075 13.1 0.1 0.22 11.6 0.0 1.8 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Herpes_UL25 PF01499.11 EXF84814.1 - 0.085 11.1 1.5 0.11 10.7 1.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Spc7 PF08317.6 EXF84814.1 - 0.12 10.9 1.3 0.18 10.4 0.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein PRCC PF10253.4 EXF84814.1 - 0.9 10.1 7.5 1.6 9.3 5.2 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting UBA PF00627.26 EXF84815.1 - 4.3e-06 26.3 0.7 2.9e-05 23.7 0.1 2.7 3 0 0 3 3 3 1 UBA/TS-N domain UBX PF00789.15 EXF84815.1 - 0.00031 20.7 0.0 0.00082 19.3 0.0 1.8 1 0 0 1 1 1 1 UBX domain zf-C2H2 PF00096.21 EXF84815.1 - 0.041 14.2 0.4 0.088 13.1 0.3 1.6 1 0 0 1 1 1 0 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EXF84815.1 - 0.045 13.8 0.7 0.088 12.9 0.2 1.7 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) CAF-1_p150 PF11600.3 EXF84815.1 - 0.14 11.4 41.5 0.22 10.8 28.8 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal SOBP PF15279.1 EXF84815.1 - 0.42 10.9 5.3 0.5 10.6 3.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein CpXC PF14353.1 EXF84815.1 - 1.2 9.0 11.5 0.93 9.4 5.9 2.3 1 1 1 2 2 2 0 CpXC protein PLRV_ORF5 PF01690.12 EXF84815.1 - 2.4 7.2 13.9 2.8 6.9 9.6 1.3 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Ribosomal_60s PF00428.14 EXF84816.1 - 9e-26 90.1 10.2 1.1e-25 89.8 7.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF2408 PF10303.4 EXF84817.1 - 1.3e-43 148.3 7.0 1.4e-26 93.1 0.0 5.2 2 2 3 5 5 5 3 Protein of unknown function (DUF2408) Laminin_II PF06009.7 EXF84817.1 - 0.13 11.9 1.9 0.48 10.1 0.3 2.4 2 0 0 2 2 2 0 Laminin Domain II IncA PF04156.9 EXF84817.1 - 2.5 7.6 9.6 0.76 9.3 3.2 2.3 1 1 1 2 2 2 0 IncA protein AMP-binding PF00501.23 EXF84819.1 - 5.7e-83 278.6 0.0 7.1e-83 278.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EXF84819.1 - 1.1e-16 61.5 0.0 2.5e-16 60.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EXF84819.1 - 0.00076 18.1 0.0 0.015 13.8 0.0 2.1 2 0 0 2 2 2 1 GH3 auxin-responsive promoter G-patch PF01585.18 EXF84820.1 - 1.7e-12 46.9 0.5 4.2e-12 45.6 0.3 1.7 1 0 0 1 1 1 1 G-patch domain RRM_5 PF13893.1 EXF84820.1 - 1.6e-06 27.8 0.0 2.8e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EXF84820.1 - 5.3e-05 22.7 0.1 0.00011 21.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF84820.1 - 0.02 14.8 0.0 0.045 13.7 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Recep_L_domain PF01030.19 EXF84821.1 - 0.0065 16.4 6.0 0.065 13.2 0.1 4.2 1 1 3 4 4 4 1 Receptor L domain Ecm33 PF12454.3 EXF84821.1 - 2.4 8.0 6.9 3 7.7 2.5 2.8 3 0 0 3 3 3 0 GPI-anchored cell wall organization protein HhH-GPD PF00730.20 EXF84822.1 - 1.8e-15 57.1 0.0 3.4e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein K_channel_TID PF07941.6 EXF84822.1 - 1.2 9.3 5.2 0.32 11.2 0.9 2.0 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain Anp1 PF03452.9 EXF84823.1 - 1e-105 352.8 0.0 1.2e-105 352.5 0.0 1.1 1 0 0 1 1 1 1 Anp1 UCR_14kD PF02271.11 EXF84824.1 - 4.6e-43 145.2 0.1 5.4e-43 145.0 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Mito_carr PF00153.22 EXF84825.1 - 2.5e-70 232.2 0.0 8.7e-24 83.0 0.0 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein HET PF06985.6 EXF84826.1 - 3.9e-20 72.4 10.5 5.5e-18 65.4 1.4 2.7 2 1 1 3 3 3 2 Heterokaryon incompatibility protein (HET) AhpC-TSA PF00578.16 EXF84827.1 - 1.1e-25 89.6 0.0 1.9e-25 88.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EXF84827.1 - 5.2e-16 58.5 0.0 7.7e-16 57.9 0.0 1.3 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EXF84827.1 - 0.00012 22.0 0.0 0.00094 19.0 0.0 1.9 1 1 1 2 2 2 1 AhpC/TSA antioxidant enzyme adh_short PF00106.20 EXF84829.1 - 1.7e-30 106.1 0.2 3.7e-30 105.0 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF84829.1 - 1.5e-25 90.3 0.1 6.8e-25 88.2 0.0 1.8 1 1 1 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF84829.1 - 1.1e-14 54.5 0.0 1.8e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF84829.1 - 0.0016 17.8 0.1 0.017 14.5 0.1 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EXF84829.1 - 0.01 14.7 0.0 0.031 13.1 0.0 1.8 1 1 0 1 1 1 0 Male sterility protein NAD_binding_10 PF13460.1 EXF84829.1 - 0.082 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 NADH(P)-binding DUF1776 PF08643.5 EXF84829.1 - 0.084 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Acetyltransf_1 PF00583.19 EXF84830.1 - 1e-14 54.3 0.1 1.8e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EXF84830.1 - 3.2e-06 26.7 0.1 5.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EXF84830.1 - 0.0002 21.4 0.2 0.0025 17.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EXF84830.1 - 0.0042 17.2 0.0 0.0076 16.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EXF84830.1 - 0.02 14.7 0.1 0.04 13.7 0.1 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Spectrin PF00435.16 EXF84831.1 - 0.025 14.8 1.1 2.4 8.4 0.0 2.1 2 0 0 2 2 2 0 Spectrin repeat Mnd1 PF03962.10 EXF84831.1 - 0.069 12.8 0.1 0.093 12.3 0.0 1.1 1 0 0 1 1 1 0 Mnd1 family DivIC PF04977.10 EXF84831.1 - 0.5 9.8 3.3 1.6 8.2 0.4 2.0 2 0 0 2 2 2 0 Septum formation initiator DUF972 PF06156.8 EXF84831.1 - 0.62 10.4 3.6 4.2 7.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Prefoldin PF02996.12 EXF84831.1 - 2.2 7.9 4.2 9.7 5.8 0.3 2.1 2 0 0 2 2 2 0 Prefoldin subunit HalX PF08663.5 EXF84831.1 - 4.8 7.2 6.4 1.2 9.1 0.8 2.0 2 0 0 2 2 2 0 HalX domain DUF4646 PF15496.1 EXF84832.1 - 1.8e-06 28.0 0.7 0.0015 18.6 0.4 3.1 2 1 0 2 2 2 1 Domain of unknown function (DUF4646) IF-2B PF01008.12 EXF84833.1 - 3.7e-41 140.9 0.0 1.2e-40 139.2 0.0 1.7 1 1 0 1 1 1 1 Initiation factor 2 subunit family NIF PF03031.13 EXF84834.1 - 4.2e-51 172.7 0.0 5.8e-51 172.3 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF1761 PF08570.5 EXF84835.1 - 3.2e-20 72.4 1.5 3.7e-20 72.2 0.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1761) Ribosomal_L7Ae PF01248.21 EXF84836.1 - 9.1e-22 76.3 0.4 3.9e-21 74.3 0.3 2.0 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HK97-gp10_like PF04883.7 EXF84836.1 - 0.1 13.5 0.1 0.1 13.5 0.1 2.3 2 0 0 2 2 2 0 Bacteriophage HK97-gp10, putative tail-component Zip PF02535.17 EXF84836.1 - 0.18 10.7 1.0 0.31 10.0 0.1 1.7 1 1 1 2 2 2 0 ZIP Zinc transporter UcrQ PF02939.11 EXF84837.1 - 1.8e-34 117.3 0.3 2.2e-34 117.1 0.2 1.1 1 0 0 1 1 1 1 UcrQ family Band_7 PF01145.20 EXF84838.1 - 1.2e-25 90.4 4.6 2e-25 89.7 3.2 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family DUF2884 PF11101.3 EXF84838.1 - 0.011 15.1 2.0 0.015 14.7 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2884) RNase_T PF00929.19 EXF84839.1 - 7.7e-09 36.0 0.0 1.2e-07 32.1 0.0 2.3 1 1 0 1 1 1 1 Exonuclease DUF676 PF05057.9 EXF84840.1 - 1.6e-51 174.7 0.0 2.5e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_5 PF12695.2 EXF84840.1 - 8.8e-07 28.7 0.0 1.6e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EXF84840.1 - 8.9e-06 25.4 0.0 1.6e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EXF84840.1 - 3.4e-05 23.8 0.1 7.1e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EXF84840.1 - 0.0043 16.6 0.0 0.0078 15.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Dispanin PF04505.7 EXF84840.1 - 0.093 12.2 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Interferon-induced transmembrane protein HhH-GPD PF00730.20 EXF84841.1 - 1.3e-16 60.8 0.0 2.4e-16 59.9 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EXF84841.1 - 3.1e-08 32.8 0.0 9.3e-08 31.3 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif Herpes_pp85 PF04637.7 EXF84841.1 - 1.5 7.0 7.3 2.3 6.4 5.0 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) zf-AN1 PF01428.11 EXF84842.1 - 1.3e-10 40.9 13.6 1.8e-10 40.4 9.4 1.2 1 0 0 1 1 1 1 AN1-like Zinc finger Ldl_recept_a PF00057.13 EXF84842.1 - 1.8 8.5 13.8 0.28 11.1 5.5 2.3 2 1 0 2 2 2 0 Low-density lipoprotein receptor domain class A ADH_N PF08240.7 EXF84843.1 - 1.5e-27 95.5 3.1 1.5e-27 95.5 2.1 2.3 3 0 0 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF84843.1 - 6e-17 61.4 0.3 1e-16 60.6 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase UDPG_MGDP_dh_N PF03721.9 EXF84843.1 - 0.018 14.4 0.2 0.03 13.6 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Nucleopor_Nup85 PF07575.8 EXF84844.1 - 8.6e-10 37.4 0.2 7e-05 21.2 0.3 3.6 2 1 0 2 2 2 2 Nup85 Nucleoporin TFIIA PF03153.8 EXF84844.1 - 0.093 12.6 3.3 0.15 11.9 2.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Daxx PF03344.10 EXF84844.1 - 1.2 7.5 9.6 1.7 7.0 6.6 1.1 1 0 0 1 1 1 0 Daxx Family DUF2457 PF10446.4 EXF84844.1 - 8.7 4.9 17.4 14 4.2 12.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) HNH PF01844.18 EXF84845.1 - 0.0003 20.5 3.2 0.00064 19.5 2.2 1.6 1 0 0 1 1 1 1 HNH endonuclease GATase PF00117.23 EXF84846.1 - 0.0038 16.6 0.0 0.0056 16.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Sororin PF09666.5 EXF84847.1 - 0.081 13.1 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Sororin protein HET PF06985.6 EXF84848.1 - 2.8e-19 69.6 6.0 4e-17 62.6 0.2 2.7 1 1 1 2 2 2 2 Heterokaryon incompatibility protein (HET) MFS_1 PF07690.11 EXF84849.1 - 4.2e-35 121.1 24.7 5.3e-35 120.7 17.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Mito_carr PF00153.22 EXF84850.1 - 1.4e-47 159.3 8.6 2e-16 59.4 0.1 4.1 4 0 0 4 4 4 4 Mitochondrial carrier protein Fungal_trans PF04082.13 EXF84851.1 - 2.4e-15 56.1 0.0 3.4e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF84851.1 - 1.8e-11 43.7 9.1 2.9e-11 43.0 6.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PrpF PF04303.8 EXF84852.1 - 1.1e-93 313.9 0.9 1.8e-84 283.6 0.2 2.0 2 0 0 2 2 2 2 PrpF protein Translin PF01997.11 EXF84853.1 - 1.2e-48 165.3 0.0 1.4e-48 165.1 0.0 1.0 1 0 0 1 1 1 1 Translin family PcfK PF14058.1 EXF84853.1 - 0.087 12.9 0.0 0.51 10.4 0.0 2.0 2 0 0 2 2 2 0 PcfK-like protein GMP_synt_C PF00958.17 EXF84853.1 - 0.1 12.3 0.1 0.29 10.8 0.1 2.1 1 1 0 1 1 1 0 GMP synthase C terminal domain ERG4_ERG24 PF01222.12 EXF84854.1 - 1.5e-140 468.5 19.4 1.8e-140 468.3 13.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ATP-synt_C PF00137.16 EXF84855.1 - 1.2e-31 108.4 29.7 1.4e-18 66.5 8.6 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Flavi_NS4A PF01350.12 EXF84855.1 - 0.38 10.3 5.7 0.12 11.9 1.7 1.7 2 0 0 2 2 2 0 Flavivirus non-structural protein NS4A DUF2970 PF11174.3 EXF84855.1 - 4.5 6.9 10.4 0.6 9.7 1.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) Ribosomal_L7Ae PF01248.21 EXF84856.1 - 9.8e-25 85.9 0.1 1.3e-24 85.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EXF84856.1 - 0.0029 17.4 0.1 0.0035 17.1 0.1 1.3 1 1 0 1 1 1 1 RNase P subunit Pop3 PELOTA_1 PF15608.1 EXF84856.1 - 0.006 16.3 0.0 0.0077 15.9 0.0 1.1 1 0 0 1 1 1 1 PELOTA RNA binding domain Syja_N PF02383.13 EXF84857.1 - 3e-97 325.2 0.0 4.3e-97 324.7 0.0 1.2 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 EXF84857.1 - 1.5e-34 117.8 0.0 2.8e-34 116.9 0.0 1.5 1 0 0 1 1 1 1 Inositol phosphatase DUF3115 PF11312.3 EXF84858.1 - 1.1e-88 297.1 0.0 1.7e-88 296.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3115) DUF979 PF06166.7 EXF84858.1 - 0.042 12.7 1.0 0.046 12.6 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF979) Transketolase_N PF00456.16 EXF84859.1 - 1.3e-152 507.3 0.0 1.8e-152 506.9 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EXF84859.1 - 4.3e-44 150.1 0.0 6.7e-44 149.4 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EXF84859.1 - 1.8e-12 47.2 0.0 3.8e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain DUF605 PF04652.11 EXF84861.1 - 0.11 11.9 17.3 0.12 11.7 12.0 1.1 1 0 0 1 1 1 0 Vta1 like Ebola_NP PF05505.7 EXF84861.1 - 1.2 7.1 9.1 1.5 6.8 6.3 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein Hid1 PF12722.2 EXF84861.1 - 3.5 5.1 5.3 4.3 4.9 3.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIF_alpha PF05793.7 EXF84861.1 - 6.4 5.0 12.1 7.8 4.7 8.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Filament PF00038.16 EXF84862.1 - 2.9e-05 23.6 17.9 2.9e-05 23.6 12.4 5.0 2 1 3 5 5 5 1 Intermediate filament protein Myosin_tail_1 PF01576.14 EXF84862.1 - 0.00027 18.8 19.1 0.00027 18.8 13.3 4.8 4 2 1 5 5 5 2 Myosin tail IncA PF04156.9 EXF84862.1 - 0.00084 18.9 58.5 0.022 14.3 12.0 4.0 3 1 1 4 4 4 3 IncA protein Tropomyosin_1 PF12718.2 EXF84862.1 - 0.012 15.4 7.8 0.012 15.4 5.4 5.8 4 2 1 5 5 5 0 Tropomyosin like HALZ PF02183.13 EXF84862.1 - 0.035 13.8 0.2 0.035 13.8 0.2 6.3 6 1 1 7 7 7 0 Homeobox associated leucine zipper Reo_sigmaC PF04582.7 EXF84862.1 - 0.07 12.2 14.6 0.16 11.1 2.8 2.8 1 1 2 3 3 3 0 Reovirus sigma C capsid protein TMF_DNA_bd PF12329.3 EXF84862.1 - 0.082 12.7 75.2 0.054 13.2 6.4 7.6 5 1 2 7 7 7 0 TATA element modulatory factor 1 DNA binding CCDC92 PF14916.1 EXF84862.1 - 0.64 9.6 0.0 0.64 9.6 0.0 4.5 5 1 1 6 6 6 0 Coiled-coil domain of unknown function DivIC PF04977.10 EXF84862.1 - 1.1 8.8 59.5 0.027 13.9 1.3 7.7 7 1 1 8 8 8 0 Septum formation initiator zf-C2H2_4 PF13894.1 EXF84863.1 - 1.3e-05 25.1 13.2 0.065 13.5 0.9 3.4 3 0 0 3 3 3 3 C2H2-type zinc finger Herpes_BLRF2 PF05812.7 EXF84863.1 - 0.00071 19.3 0.4 0.0013 18.4 0.3 1.4 1 0 0 1 1 1 1 Herpesvirus BLRF2 protein zf-C2H2 PF00096.21 EXF84863.1 - 0.0014 18.8 13.5 0.096 13.0 1.6 3.5 3 0 0 3 3 3 2 Zinc finger, C2H2 type APG6 PF04111.7 EXF84863.1 - 0.027 13.5 0.2 0.038 13.0 0.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 HALZ PF02183.13 EXF84863.1 - 0.028 14.1 0.3 0.064 12.9 0.2 1.5 1 0 0 1 1 1 0 Homeobox associated leucine zipper CCDC92 PF14916.1 EXF84863.1 - 0.035 13.6 0.2 0.067 12.7 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain of unknown function MFS_1 PF07690.11 EXF84864.1 - 2.7e-32 111.8 62.7 1.7e-28 99.3 27.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1616 PF07760.6 EXF84864.1 - 0.0015 17.7 1.4 0.0028 16.8 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1616) MFS_1 PF07690.11 EXF84865.1 - 2.8e-47 161.1 61.5 3.8e-41 140.9 21.1 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF84865.1 - 1.1e-30 106.4 15.3 1.1e-29 103.0 10.4 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EXF84865.1 - 1.2e-13 50.4 11.1 1.2e-13 50.4 7.7 3.1 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_2 PF13347.1 EXF84865.1 - 3.4e-09 35.6 31.0 1.2e-08 33.7 1.0 2.9 2 1 0 2 2 2 2 MFS/sugar transport protein 2OG-FeII_Oxy_3 PF13640.1 EXF84866.1 - 1.6e-05 25.3 0.1 2.9e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_76 PF03663.9 EXF84867.1 - 3.3e-155 517.0 12.6 4.3e-155 516.6 8.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Glyco_hydro_88 PF07470.8 EXF84867.1 - 0.005 15.9 6.9 0.11 11.5 0.1 3.3 2 1 1 3 3 3 2 Glycosyl Hydrolase Family 88 zf-MYND PF01753.13 EXF84868.1 - 0.011 15.5 2.9 0.016 15.0 2.0 1.2 1 0 0 1 1 1 0 MYND finger Bul1_N PF04425.7 EXF84868.1 - 0.3 9.6 1.1 0.36 9.3 0.8 1.2 1 0 0 1 1 1 0 Bul1 N terminus But2 PF09792.4 EXF84869.1 - 0.092 12.5 0.1 0.21 11.3 0.0 1.9 1 1 0 1 1 1 0 Ubiquitin 3 binding protein But2 C-terminal domain MACPF PF01823.14 EXF84871.1 - 2.6e-06 27.2 0.3 8.2e-06 25.6 0.0 1.8 1 1 1 2 2 2 1 MAC/Perforin domain PI-PLC-X PF00388.14 EXF84873.1 - 3.6e-09 36.1 0.0 1.4e-08 34.2 0.0 1.9 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Spc97_Spc98 PF04130.8 EXF84873.1 - 0.00018 20.0 0.0 0.00023 19.6 0.0 1.2 1 0 0 1 1 1 1 Spc97 / Spc98 family ADH_zinc_N PF00107.21 EXF84874.1 - 7.4e-24 83.7 0.0 1.4e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF84874.1 - 2.6e-22 78.6 1.3 5.2e-22 77.6 0.9 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain SIS PF01380.17 EXF84874.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 SIS domain adh_short_C2 PF13561.1 EXF84875.1 - 5.2e-33 114.8 0.0 6.2e-33 114.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EXF84875.1 - 5.2e-31 107.8 0.0 6.4e-31 107.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF84875.1 - 4e-11 42.9 0.0 5.7e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF84875.1 - 0.00064 19.2 0.0 0.0041 16.6 0.0 2.1 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EXF84875.1 - 0.0022 17.6 0.1 0.004 16.8 0.0 1.4 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EXF84875.1 - 0.0049 15.5 0.1 0.0079 14.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AdoHcyase_NAD PF00670.16 EXF84875.1 - 0.005 16.6 0.5 0.0097 15.7 0.3 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UPF0146 PF03686.8 EXF84875.1 - 0.01 15.6 0.0 0.022 14.5 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) TrkA_N PF02254.13 EXF84875.1 - 0.019 14.9 0.0 0.03 14.3 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain Polysacc_synt_2 PF02719.10 EXF84875.1 - 0.11 11.3 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein HET PF06985.6 EXF84876.1 - 8.5e-18 64.8 0.2 2.3e-17 63.4 0.2 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) ATP-grasp_2 PF08442.5 EXF84877.1 - 2.9e-46 157.4 0.0 4.2e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EXF84877.1 - 1.6e-16 60.2 1.1 2.7e-16 59.5 0.8 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EXF84877.1 - 7.5e-11 41.6 0.0 1.2e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain HipA_N PF07805.7 EXF84877.1 - 0.015 15.4 0.0 0.035 14.3 0.0 1.6 1 0 0 1 1 1 0 HipA-like N-terminal domain ATP-grasp_4 PF13535.1 EXF84877.1 - 0.062 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain SIR2 PF02146.12 EXF84878.1 - 6.7e-35 120.4 0.0 5.5e-24 84.8 0.0 2.1 2 0 0 2 2 2 2 Sir2 family Amidohydro_1 PF01979.15 EXF84880.1 - 3.6e-33 115.6 0.1 4.6e-33 115.2 0.1 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_4 PF13147.1 EXF84880.1 - 5.2e-15 56.2 0.9 7.6e-14 52.3 0.7 2.3 1 1 0 1 1 1 1 Amidohydrolase Amidohydro_5 PF13594.1 EXF84880.1 - 6.2e-13 48.3 0.4 2e-12 46.7 0.0 2.1 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EXF84880.1 - 1e-06 28.2 1.9 4.9e-05 22.7 0.1 2.7 2 1 0 2 2 2 2 Amidohydrolase family Thioredoxin_2 PF13098.1 EXF84880.1 - 0.028 14.6 0.0 0.056 13.6 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain Ank_2 PF12796.2 EXF84881.1 - 1.2e-81 269.1 0.7 2.6e-15 56.5 0.0 7.5 4 2 3 7 7 7 7 Ankyrin repeats (3 copies) Ank PF00023.25 EXF84881.1 - 1.2e-60 198.3 12.5 2.5e-07 30.1 0.0 15.5 15 0 0 15 15 15 13 Ankyrin repeat Ank_4 PF13637.1 EXF84881.1 - 4.2e-49 164.1 4.6 1.5e-07 31.7 0.0 12.6 6 4 8 14 14 14 10 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF84881.1 - 6.6e-44 143.5 1.8 8.7e-05 22.4 0.0 15.0 16 0 0 16 16 16 9 Ankyrin repeat Ank_5 PF13857.1 EXF84881.1 - 4.1e-42 141.2 5.8 8.4e-08 32.2 0.0 12.1 5 4 10 15 15 15 9 Ankyrin repeats (many copies) Shigella_OspC PF06128.6 EXF84881.1 - 0.083 12.3 0.4 5.5 6.4 0.0 3.9 4 1 2 6 6 6 0 Shigella flexneri OspC protein GMC_oxred_C PF05199.8 EXF84882.1 - 1.3e-30 106.6 0.0 2.2e-30 105.8 0.0 1.4 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_N PF00732.14 EXF84882.1 - 6.7e-27 94.4 0.0 3.7e-24 85.3 0.0 2.4 2 1 0 2 2 2 2 GMC oxidoreductase Lycopene_cycl PF05834.7 EXF84882.1 - 0.0043 16.0 0.0 0.0069 15.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EXF84882.1 - 0.0049 16.7 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF84882.1 - 0.0061 16.5 2.1 0.012 15.5 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EXF84882.1 - 0.0083 15.0 0.0 0.018 13.9 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EXF84882.1 - 0.087 11.2 0.1 0.15 10.4 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox_3 PF13738.1 EXF84882.1 - 0.095 12.7 0.0 0.53 10.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EXF84882.1 - 0.1 11.6 0.1 0.17 10.8 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Fimbrial PF00419.15 EXF84882.1 - 0.13 12.4 0.5 0.33 11.1 0.1 1.8 2 0 0 2 2 2 0 Fimbrial protein CFEM PF05730.6 EXF84883.1 - 1.2e-12 47.4 11.9 1.8e-12 46.9 8.2 1.2 1 0 0 1 1 1 1 CFEM domain Gamma-thionin PF00304.15 EXF84883.1 - 0.029 14.3 1.0 0.069 13.1 0.7 1.6 1 0 0 1 1 1 0 Gamma-thionin family G-7-MTase PF12803.2 EXF84884.1 - 0.16 11.0 1.4 0.2 10.7 1.0 1.1 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) CAF-1_p150 PF11600.3 EXF84884.1 - 0.2 10.9 6.0 0.27 10.5 4.2 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Abhydrolase_6 PF12697.2 EXF84885.1 - 8.8e-29 101.0 0.1 1.6e-28 100.1 0.1 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF84885.1 - 2.2e-16 60.1 0.2 8.1e-16 58.2 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF84885.1 - 2.8e-12 46.6 0.0 6.3e-12 45.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EXF84885.1 - 2.8e-05 23.8 0.0 4.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Ndr PF03096.9 EXF84885.1 - 0.0024 16.3 0.0 0.0035 15.8 0.0 1.1 1 0 0 1 1 1 1 Ndr family EHN PF06441.7 EXF84885.1 - 0.069 13.0 0.1 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 Epoxide hydrolase N terminus PAF-AH_p_II PF03403.8 EXF84885.1 - 0.15 10.3 0.0 0.27 9.4 0.0 1.4 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II DIOX_N PF14226.1 EXF84886.1 - 2.3e-24 86.1 0.0 3.6e-24 85.5 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EXF84886.1 - 6e-20 71.3 0.0 9.7e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NIT PF08376.5 EXF84887.1 - 0.047 13.2 2.3 0.079 12.4 1.6 1.3 1 0 0 1 1 1 0 Nitrate and nitrite sensing DUF812 PF05667.6 EXF84887.1 - 0.058 11.8 0.2 0.066 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Zn_clus PF00172.13 EXF84887.1 - 0.059 13.3 7.1 0.11 12.4 4.9 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_2 PF12756.2 EXF84888.1 - 0.0006 19.8 6.0 0.08 13.0 1.5 2.7 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EXF84888.1 - 0.0042 17.1 2.5 4.4 7.5 0.4 3.3 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.1 EXF84888.1 - 0.0045 17.2 3.8 1.2 9.6 0.0 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger HeLo PF14479.1 EXF84888.1 - 0.27 10.9 3.5 0.25 11.0 0.4 2.1 2 0 0 2 2 2 0 Prion-inhibition and propagation zf-RING_3 PF14369.1 EXF84888.1 - 0.56 10.2 3.6 1.5 8.9 0.3 2.5 2 0 0 2 2 2 0 zinc-finger zf-C2H2 PF00096.21 EXF84888.1 - 2.4 8.6 15.1 3.1 8.3 2.0 3.4 4 0 0 4 4 4 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EXF84888.1 - 4.3 7.8 5.6 8.8 6.8 1.4 2.8 2 1 0 2 2 2 0 Zinc-finger double domain zf-C2HC_2 PF13913.1 EXF84888.1 - 6.8 6.4 7.7 1.8 8.2 1.5 2.4 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Annexin PF00191.15 EXF84889.1 - 2.9e-70 232.0 4.9 2.9e-19 68.7 0.0 4.4 4 1 0 4 4 4 4 Annexin Acetyltransf_11 PF13720.1 EXF84889.1 - 0.0023 18.0 1.8 6.7 7.0 0.0 4.0 4 0 0 4 4 4 1 Udp N-acetylglucosamine O-acyltransferase; Domain 2 YqbF PF14553.1 EXF84889.1 - 0.023 14.3 1.2 4.1 7.1 0.0 2.9 3 0 0 3 3 3 0 YqbF, hypothetical protein domain DUF3574 PF12098.3 EXF84889.1 - 0.055 13.0 1.5 15 5.2 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3574) PRANC PF09372.5 EXF84892.1 - 0.065 13.1 0.3 2.3 8.2 0.0 2.3 2 0 0 2 2 2 0 PRANC domain Vps35 PF03635.12 EXF84894.1 - 0 1021.5 0.0 0 1021.3 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 RIH_assoc PF08454.6 EXF84894.1 - 0.064 12.8 0.2 0.89 9.2 0.1 3.0 3 0 0 3 3 3 0 RyR and IP3R Homology associated TFR_dimer PF04253.10 EXF84895.1 - 8.1e-21 73.8 0.0 1.6e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Transferrin receptor-like dimerisation domain Peptidase_M28 PF04389.12 EXF84895.1 - 3.7e-13 49.6 0.0 7.2e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EXF84895.1 - 8e-08 31.9 0.3 1.6e-07 30.9 0.2 1.5 1 0 0 1 1 1 1 PA domain SP_C-Propep PF08999.5 EXF84895.1 - 0.25 10.8 0.0 0.52 9.8 0.0 1.4 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide Peptidase_C48 PF02902.14 EXF84896.1 - 1.1e-18 67.7 0.0 2.2e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain FAD_binding_3 PF01494.14 EXF84897.1 - 8.6e-76 255.2 0.0 2.1e-75 254.0 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Phe_hydrox_dim PF07976.7 EXF84897.1 - 5.4e-42 143.2 0.1 8.8e-42 142.5 0.0 1.3 1 0 0 1 1 1 1 Phenol hydroxylase, C-terminal dimerisation domain Pyr_redox PF00070.22 EXF84897.1 - 0.00012 22.4 0.0 0.0014 18.9 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase XdhC_C PF13478.1 EXF84897.1 - 0.0051 17.1 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 XdhC Rossmann domain Lycopene_cycl PF05834.7 EXF84897.1 - 0.014 14.3 0.0 0.071 12.0 0.0 2.1 3 0 0 3 3 3 0 Lycopene cyclase protein Thi4 PF01946.12 EXF84897.1 - 0.021 13.9 0.0 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_8 PF13450.1 EXF84897.1 - 0.028 14.4 0.0 0.071 13.1 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF84897.1 - 0.029 14.2 0.0 0.08 12.8 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF84897.1 - 0.041 12.3 0.0 0.07 11.5 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein DUF1903 PF08991.5 EXF84898.1 - 0.083 13.0 0.1 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) Rick_17kDa_Anti PF05433.10 EXF84900.1 - 0.00036 20.1 7.5 0.027 14.1 0.6 2.5 2 0 0 2 2 2 2 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 EXF84900.1 - 0.027 14.1 0.6 0.72 9.5 0.0 2.2 2 0 0 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 EXF84900.1 - 6.2 6.4 10.6 64 3.1 7.3 2.3 1 1 0 1 1 1 0 YMGG-like Gly-zipper MFS_1 PF07690.11 EXF84901.1 - 1e-33 116.5 55.2 8.1e-24 83.9 19.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3154 PF11351.3 EXF84901.1 - 0.028 14.1 0.2 0.028 14.1 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3154) LCM PF04072.9 EXF84902.1 - 3.7e-22 78.7 0.1 5.2e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Kelch_3 PF13415.1 EXF84902.1 - 3.6e-06 26.9 0.1 0.13 12.4 0.0 4.1 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_4 PF13418.1 EXF84902.1 - 5.5e-05 22.8 3.4 0.00012 21.7 0.0 2.9 3 0 0 3 3 3 1 Galactose oxidase, central domain Kelch_6 PF13964.1 EXF84902.1 - 0.04 14.1 0.6 53 4.2 0.0 3.6 3 0 0 3 3 3 0 Kelch motif WD40 PF00400.27 EXF84903.1 - 3.9e-05 23.3 8.2 0.0012 18.6 0.0 3.9 5 0 0 5 5 5 2 WD domain, G-beta repeat Hira PF07569.6 EXF84903.1 - 0.074 12.2 0.0 0.21 10.7 0.0 1.7 2 0 0 2 2 2 0 TUP1-like enhancer of split DSPc PF00782.15 EXF84904.1 - 1.9e-25 89.0 0.0 5.4e-20 71.3 0.0 2.3 2 0 0 2 2 2 2 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EXF84904.1 - 0.00014 21.2 0.0 0.0013 18.1 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EXF84904.1 - 0.18 11.8 0.1 0.7 9.9 0.1 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate DDHD PF02862.12 EXF84905.1 - 1.6e-38 132.7 0.0 2.9e-20 73.0 0.0 3.1 3 0 0 3 3 3 2 DDHD domain Abhydrolase_6 PF12697.2 EXF84905.1 - 0.0013 18.6 0.0 0.0048 16.8 0.0 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF84905.1 - 0.0015 18.3 0.0 0.0039 16.9 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2305 PF10230.4 EXF84905.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) DUF1227 PF06777.6 EXF84906.1 - 6.5e-62 207.5 0.2 1.6e-61 206.2 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EXF84906.1 - 5.3e-53 178.9 0.6 9.5e-53 178.1 0.4 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EXF84906.1 - 4.3e-44 150.3 0.1 1.2e-43 148.9 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain SNF2_N PF00176.18 EXF84906.1 - 6.4e-05 21.8 0.0 0.00041 19.2 0.0 2.1 1 1 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EXF84906.1 - 0.00033 20.1 0.0 0.069 12.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_11 PF13086.1 EXF84906.1 - 0.0033 17.0 0.2 0.0092 15.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EXF84906.1 - 0.0074 16.1 0.0 0.028 14.2 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EXF84906.1 - 0.014 15.5 0.1 1.4 9.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EXF84906.1 - 0.029 13.5 0.0 2.2 7.4 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein Stomoxyn PF11585.3 EXF84906.1 - 0.056 13.2 0.2 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn DUF2075 PF09848.4 EXF84906.1 - 0.057 12.3 0.1 2 7.2 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.1 EXF84906.1 - 0.08 12.7 0.0 0.36 10.5 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain GST_N_3 PF13417.1 EXF84907.1 - 3.1e-05 24.0 0.0 7.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EXF84907.1 - 0.00014 21.7 0.0 0.00031 20.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EXF84907.1 - 0.00052 19.8 0.0 0.0015 18.3 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EXF84907.1 - 0.0024 18.3 0.0 0.0033 17.8 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EXF84907.1 - 0.004 17.3 0.0 0.011 15.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EXF84907.1 - 0.097 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Polyketide_cyc2 PF10604.4 EXF84909.1 - 0.00042 20.5 0.0 0.0007 19.7 0.0 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.15 EXF84909.1 - 0.013 15.5 0.0 0.022 14.7 0.0 1.4 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport WSC PF01822.14 EXF84912.1 - 8.9e-69 227.4 71.7 2e-19 69.2 6.6 5.4 5 1 0 5 5 5 4 WSC domain DUF605 PF04652.11 EXF84912.1 - 0.15 11.3 12.9 0.25 10.6 8.9 1.3 1 0 0 1 1 1 0 Vta1 like Pec_lyase_C PF00544.14 EXF84913.1 - 2.7e-25 89.0 6.4 4.3e-25 88.3 4.5 1.3 1 0 0 1 1 1 1 Pectate lyase FAD_binding_3 PF01494.14 EXF84913.1 - 0.083 11.9 1.9 1.4 7.8 0.3 2.1 1 1 0 2 2 2 0 FAD binding domain CBM-like PF14683.1 EXF84914.1 - 1.5e-40 138.6 0.3 2.9e-40 137.6 0.2 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EXF84914.1 - 4.2e-19 68.4 0.5 1.6e-18 66.6 0.4 2.1 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II CarboxypepD_reg PF13620.1 EXF84914.1 - 4.8e-09 36.1 5.2 6.8e-09 35.6 1.4 2.8 4 0 0 4 4 4 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 EXF84914.1 - 6.5e-05 22.9 0.1 0.00095 19.1 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4480) Collagen_bind_2 PF12904.2 EXF84914.1 - 0.011 15.4 0.1 0.69 9.7 0.0 3.1 3 0 0 3 3 3 0 Putative collagen-binding domain of a collagenase AAA PF00004.24 EXF84915.1 - 3.4e-08 33.7 0.1 6.4e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MFS_1 PF07690.11 EXF84917.1 - 1.2e-35 122.8 23.5 1.7e-35 122.3 16.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Fungal_trans PF04082.13 EXF84918.1 - 2.4e-21 75.8 0.0 4.2e-21 74.9 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Hydantoinase_B PF02538.9 EXF84919.1 - 5.2e-185 615.6 0.0 6.5e-185 615.3 0.0 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EXF84919.1 - 1.3e-95 319.8 0.8 2.6e-95 318.8 0.0 1.9 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EXF84919.1 - 3.6e-57 192.7 3.4 1.5e-56 190.6 0.1 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region DUF2306 PF10067.4 EXF84920.1 - 2.1e-13 50.2 6.2 2.1e-13 50.2 4.3 2.0 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) NfeD PF01957.13 EXF84920.1 - 4.5 7.4 10.9 1.2 9.3 2.0 2.7 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding PrgI PF12666.2 EXF84920.1 - 8.6 6.5 14.5 0.3 11.2 1.0 3.4 2 2 2 4 4 4 0 PrgI family protein Zn_clus PF00172.13 EXF84921.1 - 6.3e-07 29.1 12.1 1.3e-06 28.1 8.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fasciclin PF02469.17 EXF84922.1 - 2.4e-34 118.0 0.0 6.7e-20 71.3 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain Vint PF14623.1 EXF84923.1 - 1.8e-47 160.8 0.1 2.9e-47 160.1 0.0 1.3 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.1 EXF84923.1 - 3e-31 107.3 0.0 6e-31 106.3 0.0 1.5 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_2 PF13519.1 EXF84923.1 - 2.4e-20 73.3 0.0 5.3e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EXF84923.1 - 1.9e-19 70.0 0.0 3.3e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EXF84923.1 - 5.1e-13 48.9 0.0 3.7e-10 39.6 0.0 3.5 4 0 0 4 4 4 1 von Willebrand factor type A domain Hint_2 PF13403.1 EXF84923.1 - 0.029 14.3 0.2 0.071 13.0 0.0 1.8 2 0 0 2 2 2 0 Hint domain vWA-TerF-like PF10138.4 EXF84923.1 - 0.089 12.6 0.2 0.51 10.1 0.1 2.0 1 1 0 1 1 1 0 vWA found in TerF C terminus Hint PF01079.15 EXF84923.1 - 0.11 11.7 0.0 0.35 10.0 0.0 1.8 2 0 0 2 2 2 0 Hint module Peroxidase_2 PF01328.12 EXF84924.1 - 6.5e-40 136.7 0.3 6.9e-40 136.6 0.2 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Kelch_3 PF13415.1 EXF84926.1 - 7.3e-34 115.1 2.9 1.7e-07 31.2 0.0 6.3 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_4 PF13418.1 EXF84926.1 - 1.1e-29 101.8 2.6 8.4e-14 51.0 0.0 6.3 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.1 EXF84926.1 - 3.1e-18 65.1 0.4 0.0009 19.3 0.0 6.4 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.20 EXF84926.1 - 1.1e-15 56.8 0.0 0.0034 16.8 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 EXF84926.1 - 1.6e-15 56.6 1.3 0.055 13.4 0.0 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.10 EXF84926.1 - 1.7e-09 37.0 0.3 1.4 8.7 0.0 5.8 6 0 0 6 6 6 4 Kelch motif PQQ_3 PF13570.1 EXF84926.1 - 4.3 7.7 5.9 6.8 7.1 0.2 3.7 3 2 0 3 3 3 0 PQQ-like domain Acetyltransf_1 PF00583.19 EXF84927.1 - 3.1e-06 27.1 0.0 7.1e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF84927.1 - 0.00076 19.5 0.0 0.0041 17.2 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EXF84927.1 - 0.031 14.0 0.0 1.2 8.9 0.0 2.2 2 0 0 2 2 2 0 FR47-like protein Mitofilin PF09731.4 EXF84928.1 - 0.032 12.8 0.2 0.035 12.7 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein DltD_M PF04918.7 EXF84928.1 - 0.28 11.3 2.2 0.2 11.8 0.6 1.4 2 0 0 2 2 2 0 DltD central region F-box-like PF12937.2 EXF84929.1 - 0.00025 20.7 0.0 0.00066 19.3 0.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EXF84929.1 - 0.03 14.0 0.1 0.44 10.3 0.0 3.0 3 0 0 3 3 3 0 Leucine rich repeat DUF1989 PF09347.5 EXF84931.1 - 1.3e-55 187.4 0.0 1.6e-55 187.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1989) PH_6 PF15406.1 EXF84933.1 - 0.0096 15.9 0.0 0.012 15.6 0.0 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain Phage_G PF02306.10 EXF84933.1 - 0.016 14.8 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 Major spike protein (G protein) adh_short PF00106.20 EXF84934.1 - 2.1e-11 44.0 0.0 3.9e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF84934.1 - 0.00028 20.5 0.0 0.00076 19.1 0.0 1.6 2 0 0 2 2 2 1 KR domain Serglycin PF04360.7 EXF84934.1 - 0.017 14.8 0.7 0.027 14.1 0.5 1.3 1 0 0 1 1 1 0 Serglycin AAA_22 PF13401.1 EXF84934.1 - 0.043 13.9 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Epimerase PF01370.16 EXF84934.1 - 0.1 11.9 0.0 0.22 10.9 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family AAA_17 PF13207.1 EXF84934.1 - 0.12 13.2 0.0 0.19 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Shikimate_DH PF01488.15 EXF84934.1 - 0.16 12.0 0.0 0.28 11.2 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Glyco_hydro_43 PF04616.9 EXF84936.1 - 1.2e-19 70.5 0.0 1.6e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 p450 PF00067.17 EXF84937.1 - 1.2e-61 208.7 0.0 1.5e-61 208.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DASH_Spc34 PF08657.5 EXF84937.1 - 0.035 13.7 0.0 0.077 12.6 0.0 1.5 2 0 0 2 2 2 0 DASH complex subunit Spc34 BatA PF07584.6 EXF84937.1 - 0.063 13.4 1.8 0.15 12.2 1.2 1.6 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Terpene_synth_C PF03936.11 EXF84938.1 - 6.9e-08 32.0 0.4 2.3e-06 27.0 0.3 2.2 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain p450 PF00067.17 EXF84939.1 - 5.9e-61 206.3 0.0 8.1e-61 205.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 peroxidase PF00141.18 EXF84941.1 - 1.3e-24 86.9 0.0 1.8e-24 86.4 0.0 1.2 1 0 0 1 1 1 1 Peroxidase Mannosyl_trans3 PF11051.3 EXF84942.1 - 1.1e-33 116.7 0.8 4e-33 114.9 0.5 1.8 1 1 0 1 1 1 1 Mannosyltransferase putative AMP-binding PF00501.23 EXF84943.1 - 5.1e-71 239.2 0.0 6.2e-71 238.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EXF84943.1 - 1.1e-07 32.6 0.0 2.2e-07 31.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Aldolase_II PF00596.16 EXF84944.1 - 2e-29 102.4 0.8 2.7e-29 102.0 0.4 1.3 2 0 0 2 2 2 1 Class II Aldolase and Adducin N-terminal domain SUV3_C PF12513.3 EXF84944.1 - 0.079 12.4 0.0 0.22 11.0 0.0 1.8 1 0 0 1 1 1 0 Mitochondrial degradasome RNA helicase subunit C terminal AA_permease_2 PF13520.1 EXF84945.1 - 6.4e-53 179.8 51.8 8.8e-53 179.3 35.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF84945.1 - 2.5e-24 85.4 46.9 3.6e-24 84.9 32.5 1.1 1 0 0 1 1 1 1 Amino acid permease CN_hydrolase PF00795.17 EXF84946.1 - 2e-27 95.7 0.0 2.8e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Fungal_trans_2 PF11951.3 EXF84947.1 - 6.4e-23 80.9 0.9 1.3e-22 79.9 0.6 1.5 1 1 0 1 1 1 1 Fungal specific transcription factor domain TFIID-18kDa PF02269.11 EXF84948.1 - 2.9e-25 87.8 2.5 5.7e-23 80.5 0.7 2.5 2 0 0 2 2 2 2 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.18 EXF84948.1 - 0.11 12.5 1.7 6.4 6.9 0.2 3.0 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EXF84948.1 - 0.63 10.3 3.2 20 5.5 0.2 2.7 3 0 0 3 3 3 0 Transcription initiation factor TFIID subunit A Abhydrolase_6 PF12697.2 EXF84949.1 - 3.7e-26 92.4 0.0 4.8e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF84949.1 - 3.2e-18 66.1 0.0 2.1e-17 63.4 0.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF84949.1 - 1.3e-09 37.9 0.0 2.2e-09 37.2 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EXF84949.1 - 3.5e-09 36.3 0.0 8.3e-09 35.1 0.0 1.7 1 1 1 2 2 2 1 Putative lysophospholipase Ndr PF03096.9 EXF84949.1 - 2e-06 26.5 0.0 2.7e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Ndr family BAAT_C PF08840.6 EXF84949.1 - 0.00066 19.4 0.0 0.32 10.6 0.0 2.1 2 0 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Asp-B-Hydro_N PF05279.6 EXF84950.1 - 0.84 9.4 10.9 2.4 7.9 0.3 2.3 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region GPI2 PF06432.6 EXF84951.1 - 0.084 12.2 0.0 0.13 11.5 0.0 1.2 1 0 0 1 1 1 0 Phosphatidylinositol N-acetylglucosaminyltransferase YL1 PF05764.8 EXF84951.1 - 0.17 11.4 17.4 0.077 12.5 3.5 2.6 2 0 0 2 2 2 0 YL1 nuclear protein DAO PF01266.19 EXF84952.1 - 8.1e-13 47.9 0.1 2.4e-08 33.3 0.2 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF84952.1 - 4.8e-08 32.9 0.5 1.1e-07 31.7 0.3 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EXF84952.1 - 3.1e-07 29.2 0.2 6.3e-07 28.2 0.2 1.4 1 1 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EXF84952.1 - 6e-07 28.6 1.5 9.3e-07 28.0 1.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EXF84952.1 - 8e-07 28.4 0.4 1.6e-06 27.4 0.3 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EXF84952.1 - 1.4e-06 28.3 1.2 4.6e-06 26.6 0.9 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EXF84952.1 - 1.4e-06 27.6 0.2 0.0091 15.1 0.1 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Trp_halogenase PF04820.9 EXF84952.1 - 1.9e-05 23.4 0.1 0.0015 17.2 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase GIDA PF01134.17 EXF84952.1 - 0.00011 21.2 2.1 0.00018 20.5 1.5 1.4 1 1 0 1 1 1 1 Glucose inhibited division protein A FAD_oxidored PF12831.2 EXF84952.1 - 0.00014 21.1 0.6 0.00021 20.4 0.4 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EXF84952.1 - 0.00015 22.1 0.6 0.00039 20.7 0.4 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF84952.1 - 0.00027 20.7 0.9 0.16 11.7 0.1 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EXF84952.1 - 0.00033 19.7 0.1 0.3 9.9 0.1 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EXF84952.1 - 0.0015 18.6 0.3 0.0044 17.1 0.2 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EXF84952.1 - 0.0052 16.3 0.2 0.0094 15.5 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.12 EXF84952.1 - 0.018 14.1 0.2 0.028 13.5 0.2 1.3 1 0 0 1 1 1 0 Thi4 family NAD_Gly3P_dh_N PF01210.18 EXF84952.1 - 0.019 14.7 0.2 0.034 13.8 0.1 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EXF84952.1 - 0.054 12.9 0.8 0.14 11.6 0.4 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.13 EXF84952.1 - 0.088 12.4 0.1 0.15 11.7 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EXF84952.1 - 0.14 11.5 0.1 0.25 10.6 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 EXF84952.1 - 0.15 11.8 0.1 0.3 10.9 0.1 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase p450 PF00067.17 EXF84953.1 - 1.7e-76 257.6 0.0 2.2e-76 257.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_92 PF07971.7 EXF84954.1 - 5.5e-156 520.1 0.1 7.1e-156 519.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 NmrA PF05368.8 EXF84955.1 - 4.8e-26 91.4 0.0 7.9e-26 90.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF84955.1 - 4.8e-16 59.3 0.0 6.3e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF84955.1 - 0.085 12.2 0.0 1.4 8.2 0.0 2.5 2 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family SAM_2 PF07647.12 EXF84955.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Fungal_trans_2 PF11951.3 EXF84956.1 - 1.6e-24 86.2 5.1 9.8e-24 83.6 3.5 1.9 1 1 0 1 1 1 1 Fungal specific transcription factor domain NmrA PF05368.8 EXF84957.1 - 1.6e-28 99.5 0.2 1.9e-28 99.3 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF84957.1 - 9e-16 58.4 3.3 2.4e-15 57.0 0.1 2.3 3 0 0 3 3 3 1 NADH(P)-binding Saccharop_dh PF03435.13 EXF84957.1 - 1.2e-07 31.0 0.8 1.9e-07 30.4 0.6 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EXF84957.1 - 4e-05 23.1 0.3 0.00013 21.4 0.0 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EXF84957.1 - 0.00026 19.8 0.4 0.0007 18.3 0.1 1.9 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.20 EXF84957.1 - 0.019 14.8 1.0 0.041 13.7 0.7 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Shikimate_DH PF01488.15 EXF84957.1 - 0.024 14.7 0.0 0.048 13.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Rad52_Rad22 PF04098.10 EXF84957.1 - 0.037 13.7 0.1 4.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Rad52/22 family double-strand break repair protein 2-oxoacid_dh PF00198.18 EXF84957.1 - 0.068 12.4 0.4 0.17 11.1 0.1 1.7 2 0 0 2 2 2 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) ABC2_membrane PF01061.19 EXF84959.1 - 3.4e-99 330.2 56.0 3.1e-50 170.2 14.1 3.5 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 EXF84959.1 - 6.1e-37 125.4 5.7 9e-33 112.0 0.0 3.2 3 0 0 3 3 2 2 CDR ABC transporter ABC_tran PF00005.22 EXF84959.1 - 1.2e-35 122.7 0.0 2.4e-16 60.2 0.0 3.3 3 0 0 3 3 3 2 ABC transporter ABC_trans_N PF14510.1 EXF84959.1 - 3.1e-23 81.6 0.1 8.9e-23 80.1 0.0 1.9 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EXF84959.1 - 6e-08 32.3 0.0 0.00022 20.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EXF84959.1 - 2e-06 27.9 0.1 0.00014 21.9 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EXF84959.1 - 4.4e-06 25.9 0.1 0.00034 19.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 EXF84959.1 - 2e-05 24.4 0.1 0.041 13.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_29 PF13555.1 EXF84959.1 - 9.1e-05 21.9 0.4 0.024 14.1 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.14 EXF84959.1 - 0.00012 21.5 0.8 0.003 17.0 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_21 PF13304.1 EXF84959.1 - 0.00072 19.6 0.0 1.3 8.9 0.0 3.2 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.1 EXF84959.1 - 0.00072 19.6 0.1 0.56 10.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EXF84959.1 - 0.0043 16.3 0.0 2 7.6 0.0 3.5 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EXF84959.1 - 0.0055 17.5 0.0 0.67 10.7 0.0 2.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.7 EXF84959.1 - 0.0071 16.0 0.0 1.8 8.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_19 PF13245.1 EXF84959.1 - 0.0073 16.0 0.3 5 6.9 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 EXF84959.1 - 0.014 15.6 0.0 0.58 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain Miro PF08477.8 EXF84959.1 - 0.016 15.6 0.0 6.4 7.3 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein AAA_28 PF13521.1 EXF84959.1 - 0.058 13.3 0.2 0.6 10.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EXF84959.1 - 0.077 13.1 0.1 10 6.3 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EXF84959.1 - 0.1 11.9 0.2 6.6 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain UPF0079 PF02367.12 EXF84959.1 - 0.11 12.1 0.5 3.8 7.1 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 EXF84959.1 - 0.12 12.6 0.0 0.51 10.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.2 EXF84959.1 - 0.29 10.1 49.9 0.57 9.1 12.9 4.1 3 2 0 3 3 3 0 ABC-2 family transporter protein VEK-30 PF12107.3 EXF84959.1 - 0.86 9.3 3.1 0.29 10.8 0.0 1.8 2 0 0 2 2 1 0 Plasminogen (Pg) ligand in fibrinolytic pathway MFS_1 PF07690.11 EXF84960.1 - 4.7e-41 140.6 23.2 4.7e-41 140.6 16.0 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily PhaG_MnhG_YufB PF03334.9 EXF84960.1 - 8.1 6.5 14.2 0.56 10.2 3.7 3.1 2 1 0 2 2 2 0 Na+/H+ antiporter subunit Ank PF00023.25 EXF84961.1 - 2e-21 74.6 6.1 6.2e-08 32.0 0.1 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_2 PF12796.2 EXF84961.1 - 2e-21 76.1 4.0 1.5e-12 47.7 0.7 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EXF84961.1 - 3.1e-21 74.8 4.2 2.4e-10 40.3 0.5 4.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EXF84961.1 - 4.8e-16 58.7 5.3 4.3e-07 30.2 0.1 3.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF84961.1 - 1.1e-14 53.0 2.8 5.5e-05 23.0 0.1 4.4 4 0 0 4 4 4 3 Ankyrin repeat Racemase_4 PF13615.1 EXF84961.1 - 0.014 15.6 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 Putative alanine racemase Thiolase_N PF00108.18 EXF84962.1 - 1.7e-72 243.6 1.8 2.3e-72 243.1 1.3 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EXF84962.1 - 1.5e-39 134.1 1.8 3.2e-39 133.1 0.4 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain NUDIX PF00293.23 EXF84963.1 - 0.00026 20.6 0.0 0.0008 19.0 0.0 1.8 1 1 0 1 1 1 1 NUDIX domain Catalase PF00199.14 EXF84964.1 - 0.0057 15.3 0.8 0.0072 15.0 0.6 1.1 1 0 0 1 1 1 1 Catalase DUF883 PF05957.8 EXF84964.1 - 1.3 9.4 4.8 0.31 11.4 0.5 2.1 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) CoA_trans PF01144.18 EXF84966.1 - 1.2e-100 335.1 3.9 5.5e-58 195.6 0.3 2.0 2 0 0 2 2 2 2 Coenzyme A transferase AcetylCoA_hyd_C PF13336.1 EXF84966.1 - 0.00019 21.1 0.2 0.00043 19.9 0.1 1.5 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain MFS_1 PF07690.11 EXF84967.1 - 2.5e-35 121.8 28.1 2.5e-35 121.8 19.5 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EXF84967.1 - 0.00062 19.2 1.9 0.0018 17.8 1.3 1.7 1 0 0 1 1 1 1 Ion channel regulatory protein UNC-93 Mito_carr PF00153.22 EXF84969.1 - 2.6e-48 161.6 5.6 4.4e-17 61.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Fungal_trans PF04082.13 EXF84970.1 - 0.0014 17.5 0.4 0.0055 15.6 0.3 2.0 1 1 0 1 1 1 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 EXF84972.1 - 3.9e-18 65.6 0.7 5.9e-10 38.7 0.2 2.8 2 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EXF84972.1 - 2.2e-07 30.7 0.0 5.1e-07 29.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF84972.1 - 9.9e-06 24.6 0.0 2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EXF84972.1 - 8.3e-05 22.7 0.0 0.00013 22.0 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF84972.1 - 0.00034 19.5 0.3 0.00062 18.7 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.12 EXF84972.1 - 0.00044 19.4 0.0 0.00084 18.4 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EXF84972.1 - 0.00067 18.2 0.0 0.00093 17.7 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Amino_oxidase PF01593.19 EXF84972.1 - 0.0011 18.1 0.0 0.047 12.7 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.22 EXF84972.1 - 0.0017 18.7 0.0 0.0069 16.7 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EXF84972.1 - 0.0023 17.5 0.0 0.004 16.8 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EXF84972.1 - 0.0037 16.2 0.1 0.013 14.4 0.0 1.9 1 1 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EXF84972.1 - 0.0044 16.9 0.1 0.009 15.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EXF84972.1 - 0.0051 16.8 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain IlvN PF07991.7 EXF84972.1 - 0.007 15.7 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain UDPG_MGDP_dh_N PF03721.9 EXF84972.1 - 0.0078 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EXF84972.1 - 0.013 15.2 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_10 PF13460.1 EXF84972.1 - 0.013 15.4 0.3 0.067 13.1 0.0 2.2 3 0 0 3 3 3 0 NADH(P)-binding NAD_binding_9 PF13454.1 EXF84972.1 - 0.025 14.3 0.0 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EXF84972.1 - 0.033 14.2 0.0 0.068 13.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EXF84972.1 - 0.043 12.6 0.1 0.069 11.9 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A NAD_binding_2 PF03446.10 EXF84972.1 - 0.045 13.5 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.14 EXF84972.1 - 0.13 11.3 0.0 0.29 10.2 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain FMO-like PF00743.14 EXF84972.1 - 0.19 9.9 0.0 0.26 9.4 0.0 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like HycI PF01750.13 EXF84973.1 - 0.024 14.1 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase maturation protease BNR PF02012.15 EXF84974.1 - 0.034 13.9 0.2 0.16 11.8 0.2 2.3 1 0 0 1 1 1 0 BNR/Asp-box repeat Glyco_hydro_76 PF03663.9 EXF84975.1 - 2.3e-138 461.5 12.5 3.1e-138 461.1 8.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 Sensor_TM1 PF13755.1 EXF84976.1 - 0.052 13.0 0.7 0.095 12.2 0.1 1.7 2 0 0 2 2 2 0 Sensor N-terminal transmembrane domain Peptidase_MA_2 PF13485.1 EXF84977.1 - 0.0042 17.1 1.3 0.0083 16.1 0.9 1.5 1 0 0 1 1 1 1 Peptidase MA superfamily Cu-oxidase_3 PF07732.10 EXF84979.1 - 1.6e-17 63.2 0.7 8.1e-17 61.0 0.1 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase PF00394.17 EXF84979.1 - 8.5e-17 61.5 0.0 1.4e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EXF84979.1 - 2.4e-07 30.3 0.0 0.00019 20.9 0.0 2.6 2 0 0 2 2 2 2 Multicopper oxidase DUF2322 PF10084.4 EXF84979.1 - 0.12 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2322) Cu-oxidase_3 PF07732.10 EXF84980.1 - 2.1e-24 85.5 2.5 7e-22 77.3 1.7 3.2 2 1 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.9 EXF84980.1 - 3.6e-20 71.8 2.0 5.7e-17 61.5 0.3 3.3 3 0 0 3 3 3 2 Multicopper oxidase Cu-oxidase PF00394.17 EXF84980.1 - 3.6e-16 59.4 0.0 1e-15 58.0 0.0 1.8 2 0 0 2 2 2 1 Multicopper oxidase DUF2856 PF11043.3 EXF84981.1 - 0.026 14.6 0.7 0.094 12.8 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2856) Glyco_hydro_43 PF04616.9 EXF84982.1 - 5.8e-38 130.6 8.3 6.5e-38 130.4 5.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DUF1674 PF07896.7 EXF84982.1 - 2.5 8.4 6.1 0.32 11.2 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1674) Sugar_tr PF00083.19 EXF84983.1 - 3.2e-96 322.6 20.6 3.8e-96 322.4 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF84983.1 - 2.3e-28 98.9 44.4 1.1e-25 90.0 16.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF791 PF05631.9 EXF84983.1 - 0.0002 20.1 0.6 0.0002 20.1 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF791) RVP_2 PF08284.6 EXF84986.1 - 0.068 13.0 0.0 0.082 12.8 0.0 1.1 1 0 0 1 1 1 0 Retroviral aspartyl protease p450 PF00067.17 EXF84987.1 - 3.3e-74 250.0 0.0 4.2e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 DUF3074 PF11274.3 EXF84988.1 - 1.4e-42 145.4 0.0 2e-42 144.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3074) IncA PF04156.9 EXF84989.1 - 0.0074 15.9 4.5 0.013 15.1 3.1 1.3 1 0 0 1 1 1 1 IncA protein DUF1635 PF07795.6 EXF84989.1 - 0.022 14.1 3.3 0.024 14.0 1.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) DUF3921 PF13060.1 EXF84989.1 - 0.025 14.4 0.0 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3921) HOOK PF05622.7 EXF84989.1 - 0.036 11.8 6.4 0.048 11.4 4.4 1.1 1 0 0 1 1 1 0 HOOK protein DUF2408 PF10303.4 EXF84989.1 - 0.06 13.4 1.5 0.12 12.5 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) APG6 PF04111.7 EXF84989.1 - 0.49 9.4 5.5 0.73 8.8 3.8 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 OmpH PF03938.9 EXF84989.1 - 1.1 9.2 6.1 2.2 8.2 4.2 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) SlyX PF04102.7 EXF84989.1 - 1.3 9.4 5.5 0.42 11.0 1.2 2.3 2 1 0 2 2 2 0 SlyX TAFII55_N PF04658.8 EXF84990.1 - 5.9e-46 155.9 0.0 1.2e-45 154.9 0.0 1.5 1 0 0 1 1 1 1 TAFII55 protein conserved region Ribosomal_L37 PF08561.5 EXF84991.1 - 2.4e-30 103.9 7.6 3.8e-28 96.8 5.2 2.2 1 1 0 1 1 1 1 Mitochondrial ribosomal protein L37 NDUFB10 PF10249.4 EXF84992.1 - 0.0004 20.5 0.0 0.0005 20.2 0.0 1.3 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit 10 HWE_HK PF07536.9 EXF84992.1 - 0.086 13.2 0.0 0.13 12.7 0.0 1.2 1 0 0 1 1 1 0 HWE histidine kinase RRM_1 PF00076.17 EXF84993.1 - 9e-38 127.7 0.0 4.6e-18 64.6 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF84993.1 - 1e-28 99.1 0.0 2.4e-13 49.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF84993.1 - 4e-13 48.9 0.0 3.8e-06 26.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4140 PF13600.1 EXF84993.1 - 0.019 15.4 0.0 0.019 15.4 0.0 4.0 3 1 2 5 5 5 0 N-terminal domain of unknown function (DUF4140) MIP-T3 PF10243.4 EXF84993.1 - 0.76 8.1 55.3 0.94 7.8 38.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Herpes_pp38 PF04846.8 EXF84994.1 - 0.064 12.5 0.1 0.13 11.5 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein WH2 PF02205.15 EXF84995.1 - 1.6e-11 43.3 3.4 1.4e-10 40.3 0.3 2.8 3 0 0 3 3 3 2 WH2 motif Transgly PF00912.17 EXF84996.1 - 0.067 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Transglycosylase MFS_1 PF07690.11 EXF84997.1 - 0.0051 15.5 3.4 0.0068 15.1 2.4 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily 7tm_7 PF08395.7 EXF84997.1 - 0.011 14.8 6.2 0.016 14.2 4.3 1.1 1 0 0 1 1 1 0 7tm Chemosensory receptor Neur_chan_memb PF02932.11 EXF84997.1 - 0.24 11.2 2.5 0.94 9.3 0.1 2.4 2 1 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF1673 PF07895.6 EXF84997.1 - 0.37 10.3 4.5 0.4 10.1 2.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) DUF2029 PF09594.5 EXF84997.1 - 0.89 9.0 9.0 0.89 9.0 1.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2029) DUF1469 PF07332.6 EXF84997.1 - 1.4 8.6 3.6 0.62 9.7 0.3 2.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1469) DUF2516 PF10724.4 EXF84997.1 - 4 7.4 6.7 5.6 7.0 1.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2516) DUF4131 PF13567.1 EXF84997.1 - 4.2 6.7 6.8 4.3 6.7 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) CHORD PF04968.7 EXF84998.1 - 5.2e-52 173.9 17.2 1.5e-26 92.3 3.3 2.2 2 0 0 2 2 2 2 CHORD CS PF04969.11 EXF84998.1 - 4.4e-14 52.7 0.1 6.5e-14 52.2 0.1 1.3 1 0 0 1 1 1 1 CS domain DUF836 PF05768.9 EXF84999.1 - 1.5e-13 50.8 0.0 1.7e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 EXF84999.1 - 0.0012 18.7 0.0 0.002 18.0 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin HpcH_HpaI PF03328.9 EXF85000.1 - 6.4e-33 113.5 0.0 7.7e-33 113.2 0.0 1.0 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family PEP_mutase PF13714.1 EXF85000.1 - 0.081 12.1 0.0 17 4.4 0.0 2.9 2 1 1 3 3 3 0 Phosphoenolpyruvate phosphomutase SHS2_Rpb7-N PF03876.12 EXF85001.1 - 1e-15 57.6 0.0 1.7e-15 56.9 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EXF85001.1 - 8.5e-12 44.9 0.0 1.3e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 S1 RNA binding domain DUF962 PF06127.6 EXF85002.1 - 1.6e-26 92.0 0.0 2.9e-26 91.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF962) FlxA PF14282.1 EXF85005.1 - 1.2 9.0 6.6 2.4 8.1 4.6 1.4 1 1 0 1 1 1 0 FlxA-like protein Aminotran_5 PF00266.14 EXF85007.1 - 3e-23 82.1 0.0 4.8e-23 81.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V MOSC PF03473.12 EXF85007.1 - 7.2e-23 80.5 0.0 1.6e-22 79.3 0.0 1.6 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.11 EXF85007.1 - 3.1e-20 72.0 0.0 5.8e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain AAA_22 PF13401.1 EXF85008.1 - 4e-15 56.1 0.1 1.3e-14 54.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EXF85008.1 - 1.1e-13 51.5 0.5 7.1e-12 45.6 0.0 3.3 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.24 EXF85008.1 - 1.4e-10 41.4 0.0 4.1e-10 39.9 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EXF85008.1 - 3.8e-05 23.4 0.0 0.00013 21.7 0.0 1.9 1 1 0 1 1 1 1 Archaeal ATPase Cdc6_C PF09079.6 EXF85008.1 - 0.00014 21.4 0.1 0.00071 19.2 0.0 2.2 2 0 0 2 2 2 1 CDC6, C terminal AAA_30 PF13604.1 EXF85008.1 - 0.0023 17.5 0.1 0.013 15.1 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_14 PF13173.1 EXF85008.1 - 0.0035 17.2 0.0 0.0084 16.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EXF85008.1 - 0.0037 16.1 0.0 0.0064 15.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain DUF815 PF05673.8 EXF85008.1 - 0.0042 16.0 0.0 0.0099 14.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_19 PF13245.1 EXF85008.1 - 0.0064 16.2 0.1 0.037 13.7 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain Sigma54_activat PF00158.21 EXF85008.1 - 0.011 15.1 0.0 0.021 14.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain SRPRB PF09439.5 EXF85008.1 - 0.014 14.6 0.0 0.04 13.1 0.0 1.8 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit NACHT PF05729.7 EXF85008.1 - 0.02 14.5 0.0 0.043 13.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.17 EXF85008.1 - 0.031 14.4 0.0 0.079 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 EXF85008.1 - 0.038 13.7 0.1 0.15 11.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Rad17 PF03215.10 EXF85008.1 - 0.04 12.6 0.2 0.11 11.1 0.0 1.7 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein AAA_35 PF14516.1 EXF85008.1 - 0.044 12.4 0.1 0.2 10.2 0.0 1.9 2 0 0 2 2 2 0 AAA-like domain AAA_18 PF13238.1 EXF85008.1 - 0.052 13.8 0.0 0.1 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_32 PF13654.1 EXF85008.1 - 0.091 11.4 0.3 0.18 10.4 0.0 1.5 2 0 0 2 2 2 0 AAA domain RNA12 PF10443.4 EXF85008.1 - 0.099 11.1 0.3 0.51 8.7 0.0 2.1 2 1 0 2 2 2 0 RNA12 protein Rrf2 PF02082.15 EXF85008.1 - 0.1 12.7 0.0 0.33 11.1 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator KAP_NTPase PF07693.9 EXF85008.1 - 0.11 11.5 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 KAP family P-loop domain AAA_17 PF13207.1 EXF85008.1 - 0.13 13.1 0.0 0.26 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Arrestin_N PF00339.24 EXF85009.1 - 5.6e-19 68.4 0.0 2.8e-17 62.9 0.0 3.0 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EXF85009.1 - 1.5e-05 25.1 0.0 0.0031 17.6 0.0 2.7 2 1 1 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Ribosomal_L19 PF01245.15 EXF85009.1 - 0.072 12.8 0.2 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein L19 CYSTM PF12734.2 EXF85010.1 - 9.6e-05 22.3 57.4 0.043 13.8 34.2 4.0 2 1 0 2 2 2 1 Cysteine-rich TM module stress tolerance Pro-rich PF15240.1 EXF85010.1 - 2.5 8.1 24.9 3.3 7.7 17.3 1.1 1 0 0 1 1 1 0 Proline-rich Polyketide_cyc2 PF10604.4 EXF85011.1 - 0.0054 16.9 2.1 0.0071 16.5 1.0 1.6 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Dabb PF07876.7 EXF85012.1 - 1.2e-10 41.7 0.0 1.7e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain HATPase_c PF02518.21 EXF85013.1 - 1e-21 76.7 0.0 2.4e-21 75.5 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS_9 PF13426.1 EXF85013.1 - 5.3e-18 65.3 0.1 2.7e-05 24.4 0.0 4.0 3 1 0 3 3 3 3 PAS domain Response_reg PF00072.19 EXF85013.1 - 3e-17 62.6 0.6 1.3e-16 60.5 0.0 2.4 2 0 0 2 2 2 1 Response regulator receiver domain PAS_4 PF08448.5 EXF85013.1 - 1.1e-14 54.4 0.3 2.1e-05 24.5 0.0 4.4 4 1 0 4 4 4 2 PAS fold PAS PF00989.19 EXF85013.1 - 2.8e-13 49.6 0.0 0.00055 19.7 0.0 3.9 3 0 0 3 3 3 3 PAS fold HisKA PF00512.20 EXF85013.1 - 7.2e-08 32.3 0.1 3e-07 30.3 0.1 2.2 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 EXF85013.1 - 1.3e-07 31.6 0.0 0.019 15.0 0.0 4.0 3 1 0 3 3 3 2 PAS fold GAF_2 PF13185.1 EXF85013.1 - 3.3e-05 24.3 0.0 0.0073 16.8 0.0 2.6 2 0 0 2 2 2 1 GAF domain PAS_8 PF13188.1 EXF85013.1 - 0.00011 21.9 0.0 1.2 9.0 0.0 3.5 3 0 0 3 3 3 2 PAS domain GAF_3 PF13492.1 EXF85013.1 - 0.0029 17.6 0.0 0.012 15.7 0.0 2.0 2 0 0 2 2 2 1 GAF domain Mpv17_PMP22 PF04117.7 EXF85014.1 - 2.4e-13 49.5 0.4 2.4e-13 49.5 0.3 2.5 2 0 0 2 2 2 1 Mpv17 / PMP22 family Methyltransf_15 PF09445.5 EXF85014.1 - 0.056 13.0 0.0 0.08 12.5 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase UCR_6-4kD PF08997.5 EXF85014.1 - 0.076 12.7 0.0 0.48 10.1 0.0 2.1 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein YIF1 PF03878.10 EXF85015.1 - 9.2e-77 257.4 1.4 1.1e-76 257.1 1.0 1.0 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EXF85015.1 - 0.045 13.2 12.3 0.024 14.1 6.7 1.8 1 1 1 2 2 2 0 Yip1 domain SRP-alpha_N PF04086.8 EXF85016.1 - 1.7e-77 260.5 0.0 2.2e-77 260.1 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54 PF00448.17 EXF85016.1 - 5.5e-53 179.3 0.4 2.6e-52 177.1 0.1 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP54_N PF02881.14 EXF85016.1 - 1.5e-06 28.2 0.3 4.8e-06 26.5 0.1 1.9 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain ArgK PF03308.11 EXF85016.1 - 2e-05 23.5 0.0 5.1e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 ArgK protein CbiA PF01656.18 EXF85016.1 - 9.7e-05 21.8 0.2 0.00024 20.5 0.1 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MobB PF03205.9 EXF85016.1 - 0.0097 15.6 0.1 0.026 14.2 0.1 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EXF85016.1 - 0.015 15.2 0.0 0.038 13.9 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.22 EXF85016.1 - 0.024 14.9 0.1 0.15 12.3 0.0 2.3 2 1 0 2 2 2 0 ABC transporter AAA_16 PF13191.1 EXF85016.1 - 0.1 12.6 0.1 0.28 11.1 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 EXF85016.1 - 0.11 12.4 0.2 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain DUF1574 PF07611.6 EXF85017.1 - 0.93 8.2 1.1 1.7 7.4 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1574) GCR PF02155.10 EXF85018.1 - 0.0029 16.4 0.0 0.003 16.3 0.0 1.0 1 0 0 1 1 1 1 Glucocorticoid receptor Mid2 PF04478.7 EXF85019.1 - 4.5e-05 22.8 4.5 4.5e-05 22.8 3.1 1.6 1 1 0 1 1 1 1 Mid2 like cell wall stress sensor DUF533 PF04391.7 EXF85019.1 - 0.045 13.1 0.2 0.045 13.1 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF533) SKG6 PF08693.5 EXF85019.1 - 0.059 12.6 0.2 0.13 11.6 0.1 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Herpes_gE PF02480.11 EXF85019.1 - 0.078 11.2 0.0 0.12 10.6 0.0 1.4 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E Herpes_BLLF1 PF05109.8 EXF85019.1 - 1.9 6.3 19.2 2.3 6.0 13.3 1.0 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Amidohydro_1 PF01979.15 EXF85020.1 - 1e-09 38.5 0.0 2.4e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 Amidohydrolase family NMO PF03060.10 EXF85020.1 - 0.054 12.6 0.0 0.093 11.8 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase Glyco_hydro_35 PF01301.14 EXF85021.1 - 8.7e-90 301.2 0.0 1.1e-89 300.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom2 PF10435.4 EXF85021.1 - 7.2e-55 185.1 4.5 1.2e-54 184.4 3.1 1.4 1 0 0 1 1 1 1 Beta-galactosidase, domain 2 BetaGal_dom4_5 PF13364.1 EXF85021.1 - 2.6e-48 162.9 9.0 8.5e-27 93.6 2.6 3.0 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain BetaGal_dom3 PF13363.1 EXF85021.1 - 1.7e-21 75.4 0.1 3.6e-21 74.3 0.1 1.6 1 0 0 1 1 1 1 Beta-galactosidase, domain 3 SBP_bac_6 PF13343.1 EXF85022.1 - 1.2e-17 64.0 0.2 4.3e-17 62.2 0.1 1.6 1 1 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_11 PF13531.1 EXF85022.1 - 4.7e-09 36.2 0.0 7.2e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.20 EXF85022.1 - 2e-06 27.8 0.2 0.02 14.6 0.1 2.2 2 0 0 2 2 2 2 Bacterial extracellular solute-binding protein PAD PF03068.10 EXF85023.1 - 2.6e-46 157.7 0.0 4.3e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 Protein-arginine deiminase (PAD) Fungal_trans_2 PF11951.3 EXF85024.1 - 2e-07 29.9 0.2 2e-07 29.9 0.2 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Ubiq_cyt_C_chap PF03981.7 EXF85024.1 - 0.11 12.3 0.4 0.65 9.8 0.0 2.3 3 0 0 3 3 3 0 Ubiquinol-cytochrome C chaperone 2OG-FeII_Oxy PF03171.15 EXF85025.1 - 0.0076 16.5 0.1 0.046 14.0 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Cupin_2 PF07883.6 EXF85028.1 - 0.00025 20.4 0.2 0.00032 20.1 0.2 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_7 PF12973.2 EXF85028.1 - 0.025 14.3 0.0 0.055 13.3 0.0 1.6 1 1 0 1 1 1 0 ChrR Cupin-like domain PI-PLC-X PF00388.14 EXF85029.1 - 4.7e-58 194.7 0.0 8.8e-58 193.8 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EXF85029.1 - 1.2e-36 125.2 0.0 2.2e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain Cytochrome_C7 PF14522.1 EXF85030.1 - 0.093 12.3 2.1 0.16 11.6 1.4 1.5 1 1 0 1 1 1 0 Cytochrome c7 zf-MYND PF01753.13 EXF85030.1 - 0.14 12.0 4.3 0.78 9.6 0.2 2.3 1 1 0 2 2 2 0 MYND finger GCM PF03615.10 EXF85030.1 - 0.21 11.1 3.1 0.24 11.0 2.2 1.0 1 0 0 1 1 1 0 GCM motif protein FeS PF04060.8 EXF85030.1 - 0.27 10.8 9.2 0.29 10.7 3.0 2.3 2 0 0 2 2 2 0 Putative Fe-S cluster DUF2256 PF10013.4 EXF85030.1 - 1.3 8.7 5.6 9.3 6.0 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) Fungal_trans PF04082.13 EXF85031.1 - 7.2e-10 38.1 1.3 1.4e-09 37.2 0.9 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2 PF00096.21 EXF85031.1 - 2.1e-09 37.1 13.6 0.00025 21.1 0.9 3.1 2 0 0 2 2 2 2 Zinc finger, C2H2 type Zn_clus PF00172.13 EXF85031.1 - 7e-06 25.8 12.4 7e-06 25.8 8.6 2.3 2 1 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_4 PF13894.1 EXF85031.1 - 2e-05 24.5 20.4 0.00033 20.7 0.8 3.4 3 0 0 3 3 3 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EXF85031.1 - 4.5e-05 23.5 3.2 4.5e-05 23.5 2.2 2.8 3 0 0 3 3 3 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EXF85031.1 - 1.5 9.0 6.0 3.2 8.0 0.9 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_6 PF13912.1 EXF85031.1 - 8.6 6.4 12.4 5.3 7.1 1.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger F-box-like PF12937.2 EXF85032.1 - 0.021 14.5 0.0 0.071 12.8 0.0 2.0 1 0 0 1 1 1 0 F-box-like Pyrid_oxidase_2 PF13883.1 EXF85033.1 - 1.1e-40 139.1 0.0 1.6e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Robl_LC7 PF03259.12 EXF85036.1 - 2.6e-09 36.5 0.0 1.7e-05 24.2 0.0 2.1 2 0 0 2 2 2 2 Roadblock/LC7 domain Ipi1_N PF12333.3 EXF85037.1 - 2.2e-22 78.9 0.2 5.6e-22 77.6 0.0 1.8 2 0 0 2 2 2 1 Rix1 complex component involved in 60S ribosome maturation TPR_20 PF14561.1 EXF85037.1 - 0.034 14.2 0.1 0.082 13.0 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DEAD PF00270.24 EXF85038.1 - 1.2e-37 128.9 0.0 1.7e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF85038.1 - 2.9e-22 78.3 0.0 5.7e-22 77.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Aldedh PF00171.17 EXF85039.1 - 4.7e-116 387.8 0.0 5.7e-116 387.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family HAD PF12710.2 EXF85040.1 - 2e-13 50.9 0.1 4.5e-13 49.7 0.1 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EXF85040.1 - 1.4e-12 47.2 0.0 3.6e-12 45.8 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_like2 PF13246.1 EXF85040.1 - 4.4e-12 45.7 0.1 1.4e-11 44.1 0.0 1.9 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EXF85040.1 - 3e-11 44.1 2.8 2.5e-09 37.8 1.9 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EXF85040.1 - 0.0035 16.9 0.9 0.0083 15.7 0.6 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase vATP-synt_E PF01991.13 EXF85042.1 - 7.5e-65 217.9 12.0 9.2e-65 217.6 8.3 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit Mg_trans_NIPA PF05653.9 EXF85043.1 - 2.4e-17 62.8 10.0 4.4e-17 61.9 7.0 1.4 1 1 0 1 1 1 1 Magnesium transporter NIPA EamA PF00892.15 EXF85043.1 - 0.00041 20.3 0.3 0.00041 20.3 0.2 2.7 3 0 0 3 3 3 2 EamA-like transporter family Neurensin PF14927.1 EXF85043.1 - 0.011 15.0 0.3 1.3 8.3 0.1 2.6 2 0 0 2 2 2 0 Neurensin DUF373 PF04123.8 EXF85043.1 - 1.6 7.6 6.1 0.73 8.7 2.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF373) COX4_pro_2 PF07835.7 EXF85043.1 - 4 7.5 7.3 1.5 8.8 0.1 3.0 3 0 0 3 3 3 0 Bacterial aa3 type cytochrome c oxidase subunit IV Tetraspannin PF00335.15 EXF85044.1 - 7.7e-10 38.4 6.6 1e-09 38.0 4.6 1.1 1 0 0 1 1 1 1 Tetraspanin family E1-E2_ATPase PF00122.15 EXF85045.1 - 5.6e-53 179.3 0.4 5.6e-53 179.3 0.3 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EXF85045.1 - 6.5e-36 123.5 6.0 6.5e-36 123.5 4.2 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EXF85045.1 - 4.3e-29 102.4 0.0 3.6e-28 99.4 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EXF85045.1 - 4.7e-18 66.0 0.0 1.9e-17 64.0 0.0 2.1 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EXF85045.1 - 1e-13 50.4 0.0 2.9e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EXF85045.1 - 4.3e-13 49.0 0.0 9.5e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EXF85045.1 - 0.00066 19.3 0.1 0.0014 18.2 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF4591 PF15261.1 EXF85045.1 - 0.068 13.4 0.8 0.1 12.8 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4591) DUF2207 PF09972.4 EXF85045.1 - 9.3 4.6 9.6 2.2 6.7 0.0 2.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) Sugar_tr PF00083.19 EXF85047.1 - 6e-94 315.1 26.1 6.9e-94 314.9 18.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF85047.1 - 3.5e-18 65.4 53.6 7.4e-16 57.8 20.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily 4HBT PF03061.17 EXF85049.1 - 4.1e-10 39.6 0.0 5.9e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily NmrA PF05368.8 EXF85050.1 - 4.9e-16 58.6 0.0 6.7e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF85050.1 - 1.3e-13 51.3 0.2 6.2e-13 49.1 0.1 1.9 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF85050.1 - 2.8e-07 30.2 0.0 3.6e-06 26.5 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EXF85050.1 - 0.00077 19.4 0.4 0.0012 18.7 0.3 1.3 1 0 0 1 1 1 1 short chain dehydrogenase F420_oxidored PF03807.12 EXF85050.1 - 0.00082 19.7 0.3 0.0018 18.6 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3Beta_HSD PF01073.14 EXF85050.1 - 0.0013 17.4 0.0 0.002 16.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EXF85050.1 - 0.0014 18.3 0.3 0.0022 17.6 0.2 1.3 1 0 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EXF85050.1 - 0.0073 15.3 0.1 0.011 14.7 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase DapB_N PF01113.15 EXF85050.1 - 0.043 13.7 1.3 0.14 12.1 0.9 1.9 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 EXF85050.1 - 0.14 11.0 0.1 0.23 10.3 0.1 1.4 1 0 0 1 1 1 0 Male sterility protein Fungal_trans PF04082.13 EXF85051.1 - 8.9e-13 47.7 0.0 1.9e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-LITAF-like PF10601.4 EXF85053.1 - 1e-17 63.7 0.2 1.6e-17 63.1 0.1 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Sgf11 PF08209.6 EXF85053.1 - 0.023 14.0 3.3 0.064 12.5 0.4 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Zn-ribbon_8 PF09723.5 EXF85053.1 - 0.025 14.5 0.6 6.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Lar_restr_allev PF14354.1 EXF85053.1 - 0.33 11.2 1.8 0.47 10.7 0.5 1.8 2 1 0 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.2 EXF85053.1 - 0.88 9.4 0.1 0.88 9.4 0.0 2.4 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Phage_T7_tail PF03906.9 EXF85054.1 - 0.09 12.4 0.1 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Phage T7 tail fibre protein OPT PF03169.10 EXF85055.1 - 0.079 11.3 0.9 0.1 10.9 0.6 1.1 1 0 0 1 1 1 0 OPT oligopeptide transporter protein RabGAP-TBC PF00566.13 EXF85056.1 - 1.2e-29 103.3 0.0 2e-29 102.6 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain eIF2A PF08662.6 EXF85057.1 - 3e-40 138.0 3.7 4e-37 127.8 0.2 3.7 2 2 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40 PF00400.27 EXF85057.1 - 3.9e-05 23.3 0.8 1.1 9.2 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat RRM_5 PF13893.1 EXF85057.1 - 9.3e-05 22.2 0.0 0.00022 20.9 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF85057.1 - 9.5e-05 22.3 0.0 0.00065 19.6 0.0 2.4 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EXF85057.1 - 0.00025 20.5 0.0 0.00061 19.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cpn60_TCP1 PF00118.19 EXF85058.1 - 1.3e-137 459.3 8.8 1.5e-137 459.1 6.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GARS_C PF02843.11 EXF85058.1 - 0.038 14.1 0.3 0.23 11.6 0.0 2.4 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain Glyco_transf_90 PF05686.7 EXF85059.1 - 1.9e-18 66.3 1.9 1.8e-13 49.9 0.7 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 90 NACHT PF05729.7 EXF85060.1 - 3.1e-08 33.4 0.0 7e-08 32.2 0.0 1.6 1 0 0 1 1 1 1 NACHT domain PGAP1 PF07819.8 EXF85060.1 - 1.7e-05 24.5 0.0 6.6e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 PGAP1-like protein AAA_22 PF13401.1 EXF85060.1 - 1.9e-05 24.8 0.2 0.00065 19.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain Abhydrolase_6 PF12697.2 EXF85060.1 - 2.1e-05 24.5 0.0 4.7e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EXF85060.1 - 4.2e-05 22.9 0.0 9e-05 21.8 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) AAA_16 PF13191.1 EXF85060.1 - 0.0027 17.7 1.2 0.013 15.4 0.2 2.5 2 1 0 2 2 2 1 AAA ATPase domain KAP_NTPase PF07693.9 EXF85060.1 - 0.078 11.9 1.5 0.24 10.3 0.5 1.8 1 1 1 2 2 2 0 KAP family P-loop domain FA_desaturase PF00487.19 EXF85063.1 - 4.7e-27 95.0 15.5 8.1e-27 94.2 10.8 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.3 EXF85063.1 - 1.7e-07 31.3 0.1 3.8e-07 30.1 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) Peptidase_M35 PF02102.10 EXF85065.1 - 2.7e-70 236.8 13.8 3.2e-70 236.6 9.6 1.0 1 0 0 1 1 1 1 Deuterolysin metalloprotease (M35) family Aspzincin_M35 PF14521.1 EXF85065.1 - 3.7e-06 27.4 0.4 3.7e-06 27.4 0.3 1.8 1 1 1 2 2 2 1 Lysine-specific metallo-endopeptidase HRXXH PF13933.1 EXF85065.1 - 0.014 14.8 2.6 0.021 14.2 1.8 1.2 1 0 0 1 1 1 0 Putative peptidase family Ribonuc_2-5A PF06479.7 EXF85067.1 - 1.5e-42 144.5 0.0 3e-42 143.5 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.20 EXF85067.1 - 9.4e-42 142.9 0.0 1.4e-41 142.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF85067.1 - 3e-20 72.3 0.0 2.9e-19 69.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EXF85067.1 - 0.0017 17.4 0.0 0.0043 16.1 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EXF85067.1 - 0.055 12.8 0.0 0.11 11.8 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.18 EXF85067.1 - 0.056 13.1 6.5 0.14 11.8 0.1 2.9 2 1 0 3 3 3 0 Phosphotransferase enzyme family zf-C3HC4_3 PF13920.1 EXF85068.1 - 3e-05 23.5 8.9 3e-05 23.5 6.2 3.2 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Pyr_redox_2 PF07992.9 EXF85069.1 - 1.4e-25 90.3 0.5 3e-15 56.6 0.0 3.5 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF85069.1 - 2e-14 53.7 0.0 2.4e-12 47.0 0.0 2.9 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF85069.1 - 0.0088 16.1 0.3 0.33 10.9 0.1 3.0 2 1 2 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase SRI PF08236.6 EXF85069.1 - 0.1 12.5 0.2 1.5 8.8 0.0 2.4 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain NAD_binding_7 PF13241.1 EXF85069.1 - 0.11 12.7 0.3 16 5.8 0.0 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding MFS_1 PF07690.11 EXF85070.1 - 1.1e-21 76.9 54.8 2.9e-16 59.1 22.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily A_deaminase PF00962.17 EXF85071.1 - 9.1e-34 116.8 0.0 1.1e-33 116.5 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase TatD_DNase PF01026.16 EXF85071.1 - 0.0067 15.6 0.0 0.0072 15.5 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase ADH_zinc_N PF00107.21 EXF85073.1 - 6.1e-11 41.9 0.1 1.3e-10 40.9 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF85073.1 - 0.0014 18.3 0.0 0.0086 15.8 0.0 2.1 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Peptidase_S15 PF02129.13 EXF85074.1 - 2.4e-39 135.4 0.0 3e-37 128.5 0.0 2.2 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EXF85074.1 - 1.1e-19 71.1 0.3 8.4e-19 68.3 0.1 2.2 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 EXF85074.1 - 2.8e-06 27.3 0.0 4.8e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pro-kuma_activ PF09286.6 EXF85075.1 - 1.2e-28 99.9 0.2 2.5e-28 98.8 0.1 1.6 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EXF85075.1 - 1.3e-09 37.6 0.9 2e-09 36.9 0.6 1.3 1 0 0 1 1 1 1 Subtilase family Asp PF00026.18 EXF85076.1 - 2.8e-21 76.1 0.1 5.7e-21 75.0 0.1 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease p450 PF00067.17 EXF85077.1 - 3.6e-46 157.6 0.0 4.6e-46 157.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Paf1 PF03985.8 EXF85078.1 - 1.6e-49 168.8 0.2 3.3e-49 167.8 0.2 1.5 1 1 0 1 1 1 1 Paf1 Rer1 PF03248.8 EXF85079.1 - 5.4e-78 260.6 8.4 6.2e-78 260.4 5.9 1.0 1 0 0 1 1 1 1 Rer1 family ECH PF00378.15 EXF85080.1 - 1.5e-70 237.0 0.0 1.9e-70 236.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Thg1 PF04446.7 EXF85080.1 - 0.057 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 tRNAHis guanylyltransferase ECH_C PF13766.1 EXF85080.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.5 1 0 0 1 1 1 0 2-enoyl-CoA Hydratase C-terminal region SH3_9 PF14604.1 EXF85081.1 - 3.9e-08 32.7 0.2 7.7e-08 31.8 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain zf-C3HC4 PF00097.20 EXF85081.1 - 4.1e-07 29.5 4.9 4.1e-07 29.5 3.4 5.1 5 2 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EXF85081.1 - 1.2e-06 28.2 5.2 1.2e-06 28.2 3.6 4.7 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 EXF85081.1 - 1e-05 25.4 4.6 1e-05 25.4 3.2 5.3 4 3 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) SH3_1 PF00018.23 EXF85081.1 - 1.3e-05 24.5 0.1 2.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain zf-RING_6 PF14835.1 EXF85081.1 - 2.7e-05 23.8 0.3 2.7e-05 23.8 0.2 3.7 3 0 0 3 3 3 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 EXF85081.1 - 0.00014 21.4 3.8 0.00014 21.4 2.6 5.4 7 0 0 7 7 7 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EXF85081.1 - 0.00076 19.1 1.5 0.0018 17.9 1.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EXF85081.1 - 0.012 15.4 7.1 0.012 15.4 4.9 4.7 5 0 0 5 5 5 0 zinc finger of C3HC4-type, RING SH3_2 PF07653.12 EXF85081.1 - 0.02 14.3 0.2 0.054 12.9 0.0 1.8 2 0 0 2 2 2 0 Variant SH3 domain PALP PF00291.20 EXF85082.1 - 3.4e-61 207.1 0.1 3.9e-61 206.9 0.1 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ribosomal_L19 PF01245.15 EXF85084.1 - 4.1e-16 58.7 0.0 6.4e-16 58.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L19 TrkH PF02386.11 EXF85085.1 - 8e-117 389.7 9.5 8e-117 389.7 6.6 2.1 2 0 0 2 2 2 2 Cation transport protein Helicase_C_3 PF13625.1 EXF85087.1 - 1.5e-24 86.2 0.0 3.9e-23 81.5 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.10 EXF85087.1 - 3.8e-15 56.2 0.0 8.6e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EXF85087.1 - 4e-10 38.9 0.0 6.2e-10 38.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EXF85087.1 - 1.9e-09 37.2 0.0 4.4e-09 36.0 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_34 PF13872.1 EXF85087.1 - 0.072 11.8 0.0 0.13 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 zf-CHY PF05495.7 EXF85088.1 - 4.3e-14 52.4 20.3 5.6e-14 52.0 14.1 1.1 1 0 0 1 1 1 1 CHY zinc finger Zn-ribbon_8 PF09723.5 EXF85088.1 - 0.094 12.6 12.1 2.3 8.2 5.4 2.6 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1595 PF12760.2 EXF85088.1 - 0.1 12.4 11.9 2.6 7.9 5.8 2.6 2 0 0 2 2 2 0 Transposase zinc-ribbon domain zf-RING_3 PF14369.1 EXF85088.1 - 1.2 9.2 10.8 0.71 9.9 4.7 2.5 1 1 1 2 2 2 0 zinc-finger Cytochrome_C7 PF14522.1 EXF85088.1 - 1.4 8.5 13.2 2.1 8.0 9.1 1.4 1 0 0 1 1 1 0 Cytochrome c7 C1_4 PF07975.7 EXF85088.1 - 2.1 8.4 16.0 4.5 7.3 4.8 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain HypA PF01155.14 EXF85088.1 - 2.5 7.8 12.0 0.091 12.4 2.6 2.1 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Evr1_Alr PF04777.8 EXF85088.1 - 3.3 7.6 12.9 1.2e+02 2.6 8.9 2.7 1 1 0 1 1 1 0 Erv1 / Alr family Terminase_GpA PF05876.7 EXF85088.1 - 7.1 4.8 6.9 7.6 4.7 4.8 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) Proteasome PF00227.21 EXF85089.1 - 2.3e-54 183.5 0.1 3.3e-54 183.0 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EXF85089.1 - 1.8e-12 46.3 0.1 1.8e-12 46.3 0.1 1.7 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Zn_clus PF00172.13 EXF85090.1 - 8.5e-08 31.9 11.4 1.9e-07 30.8 7.9 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF85090.1 - 0.0008 18.1 0.0 0.001 17.7 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain FAD-oxidase_C PF02913.14 EXF85091.1 - 1.1e-56 191.9 0.0 1.5e-56 191.4 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EXF85091.1 - 6.6e-40 135.7 0.5 1.3e-39 134.8 0.4 1.5 1 0 0 1 1 1 1 FAD binding domain CH PF00307.26 EXF85092.1 - 9.1e-39 131.8 0.1 8.5e-19 67.6 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain EFhand_Ca_insen PF08726.5 EXF85092.1 - 4.2e-26 90.7 0.0 1.4e-25 89.0 0.0 2.0 1 0 0 1 1 1 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EXF85092.1 - 8.6e-12 44.5 0.3 6.3e-07 28.9 0.0 2.9 3 0 0 3 3 3 2 CAMSAP CH domain EF-hand_6 PF13405.1 EXF85092.1 - 0.00067 19.3 0.3 0.0077 16.0 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 EXF85092.1 - 0.012 15.2 0.9 0.1 12.2 0.1 2.7 2 1 1 3 3 3 0 EF-hand domain pair EF-hand_1 PF00036.27 EXF85092.1 - 0.07 12.4 0.3 0.5 9.8 0.0 2.5 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.1 EXF85092.1 - 0.3 11.2 2.5 1.7 8.8 1.7 2.3 1 0 0 1 1 1 0 EF-hand domain pair Hamartin PF04388.7 EXF85092.1 - 2.4 6.7 10.1 3.9 6.0 7.0 1.2 1 0 0 1 1 1 0 Hamartin protein VPS9 PF02204.13 EXF85093.1 - 3.6e-24 84.7 0.0 6.9e-24 83.8 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Sec8_exocyst PF04048.9 EXF85093.1 - 0.043 13.4 0.1 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain FlgM PF04316.8 EXF85093.1 - 0.049 13.5 0.8 0.2 11.6 0.3 2.3 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM Lipase_3 PF01764.20 EXF85094.1 - 4.7e-06 26.2 0.0 1.1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) UPF0227 PF05728.7 EXF85094.1 - 0.0025 17.5 0.0 0.0042 16.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_5 PF12695.2 EXF85094.1 - 0.028 14.1 0.0 0.073 12.8 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family YL1 PF05764.8 EXF85095.1 - 7e-57 192.7 25.7 7e-57 192.7 17.8 2.9 3 0 0 3 3 3 1 YL1 nuclear protein YL1_C PF08265.6 EXF85095.1 - 1.2e-11 43.9 0.4 1.9e-11 43.3 0.3 1.3 1 0 0 1 1 1 1 YL1 nuclear protein C-terminal domain FA_hydroxylase PF04116.8 EXF85098.1 - 1.1e-18 67.6 9.7 1.1e-18 67.6 6.7 2.3 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily TCTP PF00838.12 EXF85099.1 - 6.9e-65 218.0 0.9 7.7e-65 217.8 0.6 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein Mis12 PF05859.7 EXF85101.1 - 2.9e-37 127.6 0.4 4.9e-37 126.9 0.3 1.4 1 0 0 1 1 1 1 Mis12 protein F-box-like PF12937.2 EXF85102.1 - 8.9e-07 28.5 0.0 2.5e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like Peptidase_M14 PF00246.19 EXF85103.1 - 6e-57 193.3 0.0 7.5e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase PPR_2 PF13041.1 EXF85104.1 - 3.9e-26 90.7 0.1 1.2e-10 41.1 0.0 6.0 5 1 1 6 6 6 5 PPR repeat family PPR_3 PF13812.1 EXF85104.1 - 1.9e-18 65.0 0.1 0.0053 16.9 0.0 9.4 9 0 0 9 9 9 4 Pentatricopeptide repeat domain PPR PF01535.15 EXF85104.1 - 3.6e-10 39.1 3.0 0.025 14.5 0.1 6.8 8 0 0 8 8 8 3 PPR repeat PPR_1 PF12854.2 EXF85104.1 - 3.2e-08 32.8 0.0 0.022 14.2 0.0 4.5 4 0 0 4 4 4 3 PPR repeat ECSIT PF06239.6 EXF85104.1 - 0.0027 16.6 0.0 1.2 7.9 0.0 3.6 2 2 2 4 4 4 1 Evolutionarily conserved signalling intermediate in Toll pathway GST_N PF02798.15 EXF85105.1 - 5.5e-08 32.8 0.0 9.4e-08 32.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EXF85105.1 - 3.9e-07 30.1 0.0 9.5e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EXF85105.1 - 5.3e-06 26.3 0.0 1.8e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EXF85105.1 - 1.4e-05 24.8 0.0 2.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EXF85105.1 - 0.0026 17.6 0.0 0.0058 16.5 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EXF85105.1 - 0.0036 17.7 0.0 0.0081 16.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NDUF_B4 PF07225.7 EXF85106.1 - 0.0006 19.6 0.0 0.00063 19.5 0.0 1.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) SAP18 PF06487.7 EXF85107.1 - 1.5e-34 118.3 0.0 2e-34 117.9 0.0 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Prp18 PF02840.10 EXF85108.1 - 7.6e-52 174.9 1.0 1.4e-51 174.1 0.0 1.9 2 0 0 2 2 2 1 Prp18 domain PRP4 PF08799.6 EXF85108.1 - 1.7e-12 46.3 1.4 1.7e-12 46.3 1.0 2.9 3 0 0 3 3 3 1 pre-mRNA processing factor 4 (PRP4) like CDC27 PF09507.5 EXF85108.1 - 0.0066 15.7 17.1 0.01 15.0 11.8 1.2 1 0 0 1 1 1 1 DNA polymerase subunit Cdc27 Ycf1 PF05758.7 EXF85108.1 - 1.4 6.5 5.2 1.5 6.3 3.6 1.1 1 0 0 1 1 1 0 Ycf1 MFS_1 PF07690.11 EXF85110.1 - 1.1e-35 122.9 27.6 1.4e-35 122.6 17.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EXF85110.1 - 0.00096 18.8 1.0 0.091 12.5 0.1 3.4 3 0 0 3 3 3 1 MFS_1 like family VWA_3 PF13768.1 EXF85111.1 - 0.073 12.7 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain FAD_binding_3 PF01494.14 EXF85112.1 - 1e-78 264.9 0.0 1.3e-78 264.5 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF85112.1 - 1.6e-05 24.0 0.0 8.3e-05 21.6 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.12 EXF85112.1 - 0.00038 19.6 0.0 0.00074 18.6 0.0 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EXF85112.1 - 0.00064 19.6 0.0 0.0017 18.3 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EXF85112.1 - 0.0015 17.6 0.0 0.14 11.2 0.0 2.5 3 0 0 3 3 3 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EXF85112.1 - 0.0018 18.6 0.0 0.34 11.3 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF85112.1 - 0.0085 14.5 0.0 0.014 13.9 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EXF85112.1 - 0.079 11.7 0.0 0.15 10.8 0.0 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.9 EXF85112.1 - 0.11 12.4 0.1 0.54 10.1 0.0 2.3 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Fungal_trans PF04082.13 EXF85113.1 - 1.3e-16 60.2 3.3 2.7e-16 59.2 2.3 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF85113.1 - 1.2e-09 37.9 7.8 2.2e-09 37.0 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pectate_lyase PF03211.8 EXF85114.1 - 3.1e-66 222.8 0.2 4e-66 222.4 0.1 1.1 1 0 0 1 1 1 1 Pectate lyase p450 PF00067.17 EXF85115.1 - 2.6e-39 135.0 0.0 1.3e-37 129.4 0.0 2.7 2 1 1 3 3 3 3 Cytochrome P450 Sugar_tr PF00083.19 EXF85116.1 - 2.6e-53 181.2 4.7 3e-53 181.0 3.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF85116.1 - 2.7e-20 72.3 8.8 3.4e-20 72.0 6.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily TRI12 PF06609.8 EXF85116.1 - 2.5e-08 32.6 1.4 2.9e-08 32.3 1.0 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) MFS_2 PF13347.1 EXF85116.1 - 0.00017 20.1 3.4 0.00017 20.1 2.3 2.1 1 1 1 2 2 2 1 MFS/sugar transport protein MFS_1_like PF12832.2 EXF85116.1 - 0.018 14.7 0.3 0.044 13.5 0.2 1.6 1 0 0 1 1 1 0 MFS_1 like family PUCC PF03209.10 EXF85116.1 - 0.059 12.0 2.1 0.094 11.4 0.5 1.8 1 1 1 2 2 2 0 PUCC protein Cellulase PF00150.13 EXF85117.1 - 2.3e-30 105.7 2.7 2.3e-30 105.7 1.9 1.7 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) INCENP_N PF12178.3 EXF85117.1 - 0.058 12.9 0.0 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 Chromosome passenger complex (CPC) protein INCENP N terminal Zn_clus PF00172.13 EXF85118.1 - 1.5e-10 40.8 11.9 3e-10 39.8 8.2 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_2 PF12756.2 EXF85120.1 - 4.7e-26 90.8 0.6 8.5e-26 90.0 0.4 1.4 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) BHD_2 PF10404.4 EXF85120.1 - 0.14 12.5 1.8 0.55 10.5 0.3 2.3 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 2 DUF4407 PF14362.1 EXF85120.1 - 0.2 10.5 1.4 0.25 10.2 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1996 PF09362.5 EXF85121.1 - 1.1e-54 185.6 1.0 1.3e-54 185.3 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1996) PA14_2 PF10528.4 EXF85124.1 - 1.1e-05 25.3 0.0 1.6e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 GLEYA domain GFA PF04828.9 EXF85125.1 - 2.7e-14 52.8 0.8 2.7e-14 52.8 0.6 1.5 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Polysacc_deac_1 PF01522.16 EXF85126.1 - 3.7e-26 91.1 0.0 5.4e-26 90.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Glyco_hydro_57 PF03065.10 EXF85126.1 - 0.002 17.0 0.0 0.0032 16.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Corona_NS8 PF12093.3 EXF85126.1 - 0.044 14.1 0.0 0.76 10.1 0.0 2.3 2 0 0 2 2 2 0 Coronavirus NS8 protein adh_short PF00106.20 EXF85128.1 - 1.3e-16 60.9 0.2 4.5e-14 52.6 0.1 2.1 1 1 1 2 2 2 2 short chain dehydrogenase KR PF08659.5 EXF85128.1 - 5.2e-09 36.0 0.1 3.3e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 KR domain adh_short_C2 PF13561.1 EXF85128.1 - 3.5e-05 23.6 0.0 5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EXF85128.1 - 0.027 14.4 0.0 0.058 13.3 0.0 1.5 1 1 0 1 1 1 0 NADH(P)-binding Epimerase PF01370.16 EXF85128.1 - 0.039 13.3 0.0 0.05 13.0 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EXF85128.1 - 0.17 10.7 0.0 0.23 10.3 0.0 1.1 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ORMDL PF04061.9 EXF85130.1 - 3.1e-60 201.6 2.9 4e-60 201.2 2.0 1.1 1 0 0 1 1 1 1 ORMDL family Glyco_hydro_18 PF00704.23 EXF85132.1 - 1.4e-66 225.2 6.4 1.9e-66 224.8 4.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DUF187 PF02638.10 EXF85132.1 - 0.11 11.3 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase like GH101 Dehydratase_MU PF02288.10 EXF85133.1 - 0.035 13.8 0.9 0.074 12.8 0.6 1.5 1 0 0 1 1 1 0 Dehydratase medium subunit Mitofilin PF09731.4 EXF85133.1 - 0.1 11.2 11.2 0.11 11.1 7.8 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein RR_TM4-6 PF06459.7 EXF85133.1 - 7.8 6.2 10.4 9.7 5.9 7.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 CENP-B_dimeris PF09026.5 EXF85134.1 - 1 9.6 0.0 1 9.6 0.0 3.2 3 0 0 3 3 3 0 Centromere protein B dimerisation domain YlbD_coat PF14071.1 EXF85134.1 - 2.6 8.1 6.9 0.16 12.0 0.2 2.3 3 0 0 3 3 3 0 Putative coat protein M20_dimer PF07687.9 EXF85136.1 - 5.8e-25 87.2 0.0 1.5e-24 85.9 0.0 1.7 2 0 0 2 2 2 1 Peptidase dimerisation domain Peptidase_M20 PF01546.23 EXF85136.1 - 6e-23 81.3 0.1 7.9e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.12 EXF85136.1 - 0.01 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 ADH_zinc_N PF00107.21 EXF85137.1 - 2.3e-18 66.0 0.8 5.8e-18 64.6 0.3 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF85137.1 - 8.7e-07 29.8 0.0 2.9e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF85137.1 - 0.0015 18.2 0.0 0.0055 16.4 0.0 1.8 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain Epimerase PF01370.16 EXF85137.1 - 0.016 14.6 0.2 0.023 14.1 0.1 1.2 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family zf-MYND PF01753.13 EXF85138.1 - 0.0086 15.9 12.9 0.015 15.1 9.0 1.4 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 EXF85138.1 - 0.064 12.9 9.7 0.13 11.9 6.7 1.5 1 0 0 1 1 1 0 HIT zinc finger D123 PF07065.9 EXF85140.1 - 1.8e-16 60.0 0.0 2.5e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 D123 DUF4343 PF14243.1 EXF85140.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) Peptidase_S8 PF00082.17 EXF85144.1 - 9.5e-46 156.1 0.0 1.7e-45 155.3 0.0 1.4 1 1 0 1 1 1 1 Subtilase family PA PF02225.17 EXF85144.1 - 4.9e-06 26.1 0.0 1.1e-05 25.0 0.0 1.6 1 0 0 1 1 1 1 PA domain DUF1034 PF06280.7 EXF85144.1 - 0.00021 21.6 0.0 0.00058 20.2 0.0 1.8 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Inhibitor_I9 PF05922.11 EXF85144.1 - 0.00061 20.3 0.0 0.0012 19.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase inhibitor I9 Sugar_tr PF00083.19 EXF85145.1 - 9.9e-82 274.8 24.2 1.2e-81 274.6 16.8 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF85145.1 - 1.3e-31 109.6 49.2 2e-19 69.5 13.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EXF85145.1 - 0.01 13.9 5.4 0.12 10.4 0.8 3.0 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.2 EXF85145.1 - 0.089 12.6 3.7 1.6 8.6 0.1 3.0 3 0 0 3 3 3 0 MFS_1 like family Phage_holin_6 PF10746.4 EXF85146.1 - 3.6 7.3 5.6 0.56 9.9 0.4 2.1 2 0 0 2 2 2 0 Phage holin family 6 Myticin-prepro PF10690.4 EXF85147.1 - 0.17 11.9 0.8 0.2 11.7 0.2 1.4 1 1 0 1 1 1 0 Myticin pre-proprotein from the mussel Peptidase_A4 PF01828.12 EXF85148.1 - 3.1e-71 238.7 12.7 3.7e-71 238.4 8.8 1.1 1 0 0 1 1 1 1 Peptidase A4 family MacB_PCD PF12704.2 EXF85148.1 - 0.026 14.1 3.2 0.2 11.2 0.1 2.2 2 0 0 2 2 2 0 MacB-like periplasmic core domain PASTA PF03793.14 EXF85148.1 - 0.35 10.5 3.7 1.2 8.8 0.4 3.3 4 0 0 4 4 4 0 PASTA domain Peptidase_S10 PF00450.17 EXF85149.1 - 2.2e-84 284.0 1.9 3e-84 283.5 1.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase HET PF06985.6 EXF85150.1 - 1.5e-09 38.1 0.0 5.5e-09 36.3 0.0 1.9 2 0 0 2 2 2 1 Heterokaryon incompatibility protein (HET) Peptidase_C14 PF00656.17 EXF85151.1 - 2e-26 93.2 0.0 3.1e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Caspase domain Raptor_N PF14538.1 EXF85151.1 - 0.092 12.5 0.1 0.64 9.8 0.1 2.2 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain Pyridoxal_deC PF00282.14 EXF85152.1 - 1.3e-15 56.7 0.0 1.7e-14 53.0 0.0 2.1 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.16 EXF85152.1 - 0.017 14.3 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase CHAT PF12770.2 EXF85154.1 - 1.9e-34 119.0 0.0 3.4e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 CHAT domain TPR_12 PF13424.1 EXF85154.1 - 0.00019 21.3 13.0 5.4 7.0 0.7 7.1 5 3 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.12 EXF85154.1 - 0.053 13.4 1.9 29 4.8 0.1 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EXF85154.1 - 1 9.1 3.4 8.5 6.1 0.1 3.9 5 0 0 5 5 5 0 Tetratricopeptide repeat ECH PF00378.15 EXF85155.1 - 9.4e-32 110.0 0.0 1.2e-31 109.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family adh_short PF00106.20 EXF85156.1 - 3.4e-14 53.0 0.0 6.1e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF85156.1 - 1.6e-06 27.9 0.2 4.4e-06 26.4 0.0 1.7 2 1 0 2 2 2 1 KR domain Polysacc_synt_2 PF02719.10 EXF85156.1 - 0.0085 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short_C2 PF13561.1 EXF85156.1 - 0.02 14.6 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Tub_2 PF04525.7 EXF85157.1 - 4.5e-23 81.6 0.0 5.4e-23 81.3 0.0 1.0 1 0 0 1 1 1 1 Tubby C 2 Bac_rhamnosid PF05592.6 EXF85158.1 - 3.6e-22 78.2 0.3 2.7e-21 75.4 0.3 2.2 2 2 0 2 2 2 1 Bacterial alpha-L-rhamnosidase DUF608 PF04685.8 EXF85158.1 - 3.8e-07 29.1 0.0 8.7e-07 27.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF608 Trehalase PF01204.13 EXF85158.1 - 0.017 13.8 0.0 0.024 13.2 0.0 1.1 1 0 0 1 1 1 0 Trehalase YCII PF03795.9 EXF85159.1 - 3e-11 43.3 0.0 3.8e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Fungal_trans PF04082.13 EXF85160.1 - 4e-18 65.2 0.0 7e-18 64.4 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF85160.1 - 0.0074 16.1 5.0 0.013 15.3 3.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Flavin_Reduct PF01613.13 EXF85161.1 - 1.6e-18 66.9 0.0 2.5e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Flavin reductase like domain Pyridox_oxidase PF01243.15 EXF85161.1 - 0.021 14.8 0.0 0.039 13.9 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Pro_dh PF01619.13 EXF85163.1 - 1.8e-39 135.6 0.0 2.4e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Proline dehydrogenase MFS_1 PF07690.11 EXF85165.1 - 9.7e-28 96.8 65.5 1.3e-23 83.2 24.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EXF85165.1 - 0.0033 15.8 22.3 0.018 13.4 6.3 2.5 2 1 1 3 3 3 2 MFS/sugar transport protein Arrestin_C PF02752.17 EXF85166.1 - 7.6e-10 39.0 0.0 2.6e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EXF85166.1 - 0.00023 21.0 0.1 0.00057 19.7 0.1 1.6 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain LDB19 PF13002.2 EXF85166.1 - 0.005 16.3 0.0 0.0096 15.4 0.0 1.4 1 0 0 1 1 1 1 Arrestin_N terminal like Exo_endo_phos PF03372.18 EXF85168.1 - 1.1e-11 45.1 0.1 1.4e-11 44.7 0.1 1.1 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EXF85168.1 - 0.00033 20.2 0.0 0.00061 19.3 0.0 1.5 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase LIP PF03583.9 EXF85169.1 - 2.2e-09 36.9 0.6 7.1e-08 31.9 0.4 2.5 1 1 0 1 1 1 1 Secretory lipase Abhydrolase_5 PF12695.2 EXF85169.1 - 8.3e-09 35.3 0.8 1.7e-08 34.2 0.5 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF85169.1 - 2.7e-08 33.9 0.9 4.4e-08 33.2 0.6 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF85169.1 - 0.00065 18.9 1.1 0.011 14.9 0.0 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 EXF85169.1 - 0.0011 18.2 0.1 0.013 14.7 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Epimerase PF01370.16 EXF85170.1 - 4.2e-08 32.9 0.0 6.5e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EXF85170.1 - 0.0078 16.1 0.0 0.038 13.8 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EXF85170.1 - 0.05 13.2 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 KR domain NAD_binding_4 PF07993.7 EXF85170.1 - 0.094 11.6 0.0 0.32 9.8 0.0 1.8 1 1 0 1 1 1 0 Male sterility protein HhH-GPD PF00730.20 EXF85171.1 - 4.8e-06 26.8 0.0 9.1e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein Trep_dent_lipo PF09710.5 EXF85171.1 - 0.21 10.2 0.9 0.32 9.6 0.7 1.2 1 0 0 1 1 1 0 Treponema clustered lipoprotein (Trep_dent_lipo) ABC_tran PF00005.22 EXF85172.1 - 2e-31 109.0 0.0 5.1e-31 107.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EXF85172.1 - 2.6e-17 63.1 3.6 4.5e-17 62.3 2.5 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EXF85172.1 - 2.1e-06 27.1 0.0 0.0003 20.1 0.0 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EXF85172.1 - 0.00072 19.5 0.1 0.0023 17.9 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain PBP1_TM PF14812.1 EXF85172.1 - 0.0016 18.7 0.5 0.0038 17.4 0.3 1.6 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF258 PF03193.11 EXF85172.1 - 0.0018 17.4 0.0 0.0047 16.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 EXF85172.1 - 0.0026 17.7 0.1 0.1 12.5 0.0 2.4 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EXF85172.1 - 0.0029 16.7 0.0 0.0056 15.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.1 EXF85172.1 - 0.0039 17.3 0.0 0.021 14.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EXF85172.1 - 0.019 14.4 0.1 0.063 12.8 0.0 1.9 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF87 PF01935.12 EXF85172.1 - 0.032 14.0 0.0 0.084 12.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF87 DUF815 PF05673.8 EXF85172.1 - 0.045 12.6 0.0 0.092 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mo-co_dimer PF03404.11 EXF85172.1 - 0.076 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Mo-co oxidoreductase dimerisation domain MMR_HSR1 PF01926.18 EXF85172.1 - 0.078 12.9 0.0 0.4 10.6 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_23 PF13476.1 EXF85172.1 - 0.15 12.3 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain FAD_binding_3 PF01494.14 EXF85173.1 - 8.6e-13 48.0 1.4 2.9e-08 33.1 0.0 3.1 3 0 0 3 3 3 2 FAD binding domain Trp_halogenase PF04820.9 EXF85173.1 - 0.015 13.9 0.4 0.46 9.0 0.0 2.7 3 0 0 3 3 3 0 Tryptophan halogenase PhyH PF05721.8 EXF85174.1 - 2.6e-09 37.4 0.0 4.6e-09 36.6 0.0 1.4 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EXF85174.1 - 4.1e-05 22.2 0.0 0.026 13.0 0.0 2.9 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.1 EXF85174.1 - 0.028 14.7 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase MFS_1 PF07690.11 EXF85175.1 - 1.4e-14 53.5 19.5 1.4e-14 53.5 13.5 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF85175.1 - 1.3e-08 33.8 33.2 4.1e-07 28.9 23.0 3.2 1 1 0 1 1 1 1 Sugar (and other) transporter Peptidase_S15 PF02129.13 EXF85176.1 - 8.7e-37 127.0 0.1 1.2e-35 123.3 0.0 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PepX_C PF08530.5 EXF85176.1 - 2e-28 99.7 0.0 2.7e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Abhydrolase_6 PF12697.2 EXF85176.1 - 7.9e-07 29.1 0.0 1.3e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF85176.1 - 0.045 13.4 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EXF85176.1 - 0.079 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Putative lysophospholipase PhyH PF05721.8 EXF85177.1 - 0.00013 22.0 0.0 0.00043 20.3 0.0 1.9 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EXF85177.1 - 0.0017 16.9 0.2 0.19 10.1 0.1 2.8 2 1 1 3 3 3 2 Protein of unknown function (DUF1479) Fungal_trans PF04082.13 EXF85178.1 - 1.4e-25 89.6 0.0 2.2e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF85178.1 - 4.1e-10 39.4 12.0 7.2e-10 38.6 8.3 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain EndIII_4Fe-2S PF10576.4 EXF85178.1 - 0.033 14.3 2.9 0.11 12.7 2.0 2.0 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Toxin_23 PF08093.6 EXF85179.1 - 5.5 7.0 12.0 7.6 6.5 8.3 1.2 1 0 0 1 1 1 0 Magi 5 toxic peptide family PAS_3 PF08447.6 EXF85180.1 - 0.11 12.5 0.0 0.24 11.5 0.0 1.5 1 0 0 1 1 1 0 PAS fold H_lectin PF09458.5 EXF85181.1 - 6.1e-47 157.1 0.0 2.9e-15 55.6 0.0 3.4 3 0 0 3 3 3 3 H-type lectin domain Astacin PF01400.19 EXF85181.1 - 6e-06 25.7 0.1 2.3e-05 23.8 0.1 2.0 1 1 0 1 1 1 1 Astacin (Peptidase family M12A) Peptidase_M10 PF00413.19 EXF85181.1 - 2e-05 24.3 2.2 7.6e-05 22.4 1.5 1.9 1 1 0 1 1 1 1 Matrixin Reprolysin_5 PF13688.1 EXF85181.1 - 0.00013 21.9 0.0 0.0005 20.0 0.0 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12 DUF3810 PF12725.2 EXF85181.1 - 0.0047 15.8 0.7 0.0088 14.9 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3810) Reprolysin_3 PF13582.1 EXF85181.1 - 0.005 17.3 0.4 0.012 16.1 0.0 1.8 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EXF85181.1 - 0.013 15.0 0.0 0.025 14.0 0.0 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EXF85181.1 - 0.019 14.9 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF1025 PF06262.6 EXF85181.1 - 0.13 12.0 0.2 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 Possibl zinc metallo-peptidase PID_2 PF14719.1 EXF85181.1 - 0.15 11.6 0.0 4.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) COesterase PF00135.23 EXF85182.1 - 1.2e-60 205.7 0.1 1.4e-60 205.5 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF85182.1 - 0.06 12.9 0.2 0.31 10.5 0.1 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold HET PF06985.6 EXF85184.1 - 7.7e-20 71.4 0.0 1.5e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aldo_ket_red PF00248.16 EXF85186.1 - 1.2e-59 201.5 0.0 1.3e-59 201.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family ADH_N PF08240.7 EXF85187.1 - 8e-15 54.5 0.0 2e-14 53.2 0.0 1.7 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF85187.1 - 8.6e-07 28.5 0.3 2.6e-06 27.0 0.2 1.8 1 1 0 1 1 1 1 Zinc-binding dehydrogenase HI0933_like PF03486.9 EXF85187.1 - 0.00013 20.5 0.1 0.00017 20.1 0.1 1.1 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EXF85187.1 - 0.0098 14.7 1.2 0.015 14.1 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF85187.1 - 0.058 12.2 0.7 0.083 11.7 0.5 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DUF4419 PF14388.1 EXF85188.1 - 0.008 15.4 0.0 0.0091 15.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Glyco_hydro_43 PF04616.9 EXF85189.1 - 7.6e-49 166.3 0.4 9.4e-49 166.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 CBM_6 PF03422.10 EXF85189.1 - 2.8e-31 108.2 0.3 5.7e-31 107.2 0.2 1.6 1 0 0 1 1 1 1 Carbohydrate binding module (family 6) Glyco_hydro_32N PF00251.15 EXF85189.1 - 0.00095 18.6 0.2 0.0015 17.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 32 N-terminal domain GCM PF03615.10 EXF85190.1 - 0.014 15.0 0.0 0.024 14.2 0.0 1.3 1 1 0 1 1 1 0 GCM motif protein HET PF06985.6 EXF85191.1 - 1.4e-20 73.8 0.0 2.6e-20 73.0 0.0 1.5 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Glyco_tranf_2_3 PF13641.1 EXF85193.1 - 1.3e-25 90.5 0.0 1.8e-25 90.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EXF85193.1 - 5.5e-18 65.2 0.0 8.5e-18 64.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_trans_2_3 PF13632.1 EXF85193.1 - 1.5e-17 63.9 0.5 1.5e-17 63.9 0.3 2.5 2 1 1 3 3 3 1 Glycosyl transferase family group 2 Glyco_transf_21 PF13506.1 EXF85193.1 - 5.1e-17 61.6 0.0 7.8e-17 61.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Cellulose_synt PF03552.9 EXF85193.1 - 1e-05 24.1 0.6 0.0025 16.2 0.1 2.3 2 0 0 2 2 2 2 Cellulose synthase Glyco_tranf_2_2 PF10111.4 EXF85193.1 - 0.02 13.9 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase like family 2 Glyco_hydro_12 PF01670.11 EXF85194.1 - 3e-15 56.3 6.5 2.6e-13 50.0 1.8 3.0 2 1 1 3 3 3 3 Glycosyl hydrolase family 12 UDPG_MGDP_dh_N PF03721.9 EXF85196.1 - 1.9e-32 112.1 0.0 1e-18 67.3 0.1 2.1 1 1 1 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 EXF85196.1 - 0.004 17.0 0.0 0.14 11.9 0.0 2.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.18 EXF85196.1 - 0.027 14.1 0.5 0.25 11.0 0.1 2.2 2 1 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Saccharop_dh PF03435.13 EXF85196.1 - 0.034 13.1 0.0 0.041 12.8 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase 3HCDH_N PF02737.13 EXF85196.1 - 0.077 12.6 0.0 0.21 11.1 0.0 1.8 1 1 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.11 EXF85196.1 - 0.082 12.3 0.0 0.14 11.6 0.0 1.4 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Glyco_hydro_43 PF04616.9 EXF85197.1 - 1.2e-19 70.5 0.5 1.7e-19 70.0 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 RTA1 PF04479.8 EXF85198.1 - 4e-24 85.3 5.7 5.6e-24 84.8 3.9 1.1 1 0 0 1 1 1 1 RTA1 like protein Peptidase_M10 PF00413.19 EXF85198.1 - 1.7e-08 34.2 1.0 5e-08 32.8 0.0 2.2 3 1 0 3 3 3 1 Matrixin Reprolysin_2 PF13574.1 EXF85198.1 - 2.5e-06 27.6 0.0 5e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.1 EXF85198.1 - 7.8e-06 25.5 0.0 1.3e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_5 PF13688.1 EXF85198.1 - 8e-05 22.6 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Peptidase_M57 PF12388.3 EXF85198.1 - 0.0013 18.1 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Dual-action HEIGH metallo-peptidase Peptidase_M43 PF05572.8 EXF85198.1 - 0.0015 18.1 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_3 PF13582.1 EXF85198.1 - 0.0016 18.9 0.0 0.0036 17.8 0.0 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M48 PF01435.13 EXF85198.1 - 0.14 11.6 0.1 0.32 10.5 0.0 1.6 2 0 0 2 2 2 0 Peptidase family M48 p450 PF00067.17 EXF85199.1 - 5.8e-35 120.7 0.0 7e-35 120.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EXF85200.1 - 1.8e-60 204.7 0.0 2.1e-60 204.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GerA PF03323.8 EXF85200.1 - 0.14 10.3 0.2 0.2 9.7 0.1 1.1 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein CcmH PF03918.9 EXF85201.1 - 0.1 11.5 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Cytochrome C biogenesis protein Tnp_zf-ribbon_2 PF13842.1 EXF85201.1 - 1.2 9.6 6.4 0.56 10.6 1.3 2.1 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon MFS_1 PF07690.11 EXF85202.1 - 2.5e-40 138.2 82.5 4.6e-38 130.8 35.1 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF85202.1 - 4.3e-14 51.6 15.3 5.9e-14 51.1 10.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) FSH1 PF03959.8 EXF85203.1 - 1.2e-28 100.0 0.0 2.5e-27 95.7 0.0 2.2 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EXF85203.1 - 1.8e-08 34.5 0.6 2.7e-08 34.0 0.4 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EXF85203.1 - 0.0069 15.8 1.0 0.11 11.8 0.7 2.3 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EXF85203.1 - 0.096 12.4 0.0 0.16 11.7 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family MFS_1 PF07690.11 EXF85204.1 - 4.9e-21 74.8 31.1 4.9e-21 74.8 21.6 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EXF85204.1 - 0.004 15.6 5.7 0.004 15.6 3.9 3.7 3 1 0 3 3 3 2 MFS/sugar transport protein Dynactin_p62 PF05502.8 EXF85204.1 - 0.087 11.5 0.4 0.12 11.0 0.3 1.1 1 0 0 1 1 1 0 Dynactin p62 family GFA PF04828.9 EXF85205.1 - 1.2e-07 31.5 0.6 2.4e-07 30.6 0.4 1.5 1 1 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme p450 PF00067.17 EXF85206.1 - 7.5e-56 189.5 0.1 9.5e-56 189.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MBOAT_2 PF13813.1 EXF85207.1 - 6.7e-19 67.7 2.4 6.7e-19 67.7 1.7 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family ketoacyl-synt PF00109.21 EXF85208.1 - 4.8e-71 239.2 0.0 1.2e-70 237.9 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.5 EXF85208.1 - 2.4e-61 206.5 0.3 6.9e-61 205.0 0.2 1.9 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 EXF85208.1 - 1.2e-51 175.9 0.3 2.2e-51 175.0 0.2 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EXF85208.1 - 1.6e-50 171.9 0.0 3e-50 171.0 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EXF85208.1 - 1.8e-45 154.8 8.7 6.8e-45 152.9 0.0 3.2 3 0 0 3 3 3 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EXF85208.1 - 7.6e-33 112.8 0.4 9.7e-32 109.3 0.0 2.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EXF85208.1 - 1.6e-11 43.9 0.5 7.3e-11 41.7 0.3 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EXF85208.1 - 1.8e-05 24.9 0.0 4.7e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 EXF85208.1 - 5.5e-05 22.8 0.3 0.00014 21.5 0.2 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III PF08545.5 EXF85208.1 - 0.0046 16.5 1.2 0.02 14.5 0.0 2.7 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.18 EXF85208.1 - 0.0085 15.1 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Zn_clus PF00172.13 EXF85209.1 - 7.6e-09 35.3 8.9 7.6e-09 35.3 6.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N PF00107.21 EXF85210.1 - 9.6e-19 67.2 0.1 1.5e-18 66.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF85210.1 - 2.6e-07 31.5 0.0 5.7e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FSH1 PF03959.8 EXF85211.1 - 2.2e-22 79.5 0.0 6.3e-22 78.0 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EXF85212.1 - 1.4e-13 51.2 0.0 2e-13 50.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF85212.1 - 1.8e-11 43.9 0.0 4.4e-11 42.7 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family AXE1 PF05448.7 EXF85212.1 - 1.2e-09 37.1 0.0 5.5e-06 25.1 0.0 2.1 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.16 EXF85212.1 - 0.00051 19.3 0.0 0.067 12.4 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family BAAT_C PF08840.6 EXF85212.1 - 0.0048 16.6 0.0 0.0074 16.0 0.0 1.3 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal KR PF08659.5 EXF85213.1 - 4.8e-52 176.2 1.6 2.1e-51 174.1 1.1 2.2 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 EXF85213.1 - 7.1e-51 173.4 0.0 1.1e-50 172.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EXF85213.1 - 2.6e-49 167.9 0.0 4.5e-49 167.1 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase ketoacyl-synt PF00109.21 EXF85213.1 - 6.5e-44 150.3 0.0 4.4e-32 111.5 0.0 2.6 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain adh_short PF00106.20 EXF85213.1 - 5.9e-39 133.6 1.5 3e-38 131.3 1.1 2.4 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EXF85213.1 - 2.9e-35 120.6 0.1 1.1e-34 118.8 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EXF85213.1 - 2.3e-17 62.7 0.0 6.9e-17 61.2 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF85213.1 - 4.5e-15 56.6 0.0 3e-14 53.9 0.0 2.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EXF85213.1 - 4e-06 26.9 0.0 1.2e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 EXF85213.1 - 0.0013 19.1 0.0 0.12 12.8 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF85213.1 - 0.0067 16.1 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain p450 PF00067.17 EXF85214.1 - 3.2e-50 170.9 0.0 4.4e-25 88.1 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 AMP-binding PF00501.23 EXF85215.1 - 2.4e-62 210.6 0.0 3.8e-62 210.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme FAD_binding_4 PF01565.18 EXF85215.1 - 1.7e-16 59.9 2.7 4.8e-16 58.5 1.8 1.8 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF85215.1 - 1.8e-10 40.5 0.2 3.7e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 Berberine and berberine like Cytokin-bind PF09265.5 EXF85215.1 - 0.26 10.3 0.0 0.42 9.7 0.0 1.3 1 0 0 1 1 1 0 Cytokinin dehydrogenase 1, FAD and cytokinin binding adh_short PF00106.20 EXF85216.1 - 6.8e-13 48.8 0.2 1.1e-12 48.1 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF85216.1 - 2.5e-05 24.0 0.2 4.1e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF85216.1 - 0.0025 17.5 0.0 0.0035 17.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EXF85216.1 - 0.021 14.8 0.1 0.053 13.5 0.1 1.6 1 1 0 1 1 1 0 NADH(P)-binding bZIP_2 PF07716.10 EXF85217.1 - 0.00025 20.8 7.1 0.00051 19.8 5.0 1.5 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EXF85217.1 - 0.0049 16.7 11.1 0.018 14.9 7.7 1.9 1 1 0 1 1 1 1 bZIP transcription factor LolA PF03548.10 EXF85218.1 - 0.071 12.7 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 Outer membrane lipoprotein carrier protein LolA Abhydrolase_6 PF12697.2 EXF85219.1 - 1.6e-34 119.7 0.1 2e-34 119.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF85219.1 - 4.9e-17 62.2 0.1 1.1e-15 57.8 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF85219.1 - 2.2e-16 59.9 0.0 2.9e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EXF85219.1 - 4.1e-06 25.4 0.0 6.9e-06 24.7 0.0 1.3 1 0 0 1 1 1 1 Ndr family Peptidase_S9 PF00326.16 EXF85219.1 - 0.00032 19.9 0.0 0.0049 16.1 0.0 2.2 1 1 0 2 2 2 1 Prolyl oligopeptidase family Pax2_C PF12403.3 EXF85219.1 - 0.018 14.6 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Paired-box protein 2 C terminal QCR10 PF09796.4 EXF85219.1 - 0.031 13.9 0.1 0.93 9.2 0.0 2.4 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Esterase_phd PF10503.4 EXF85219.1 - 0.046 12.9 0.0 0.69 9.1 0.0 2.4 3 0 0 3 3 3 0 Esterase PHB depolymerase FSH1 PF03959.8 EXF85219.1 - 0.099 12.0 0.0 2.2 7.6 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_4 PF08386.5 EXF85219.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein MFS_1 PF07690.11 EXF85220.1 - 5.5e-35 120.7 18.3 5.5e-35 120.7 12.7 1.5 2 0 0 2 2 2 1 Major Facilitator Superfamily DUF3040 PF11239.3 EXF85220.1 - 0.014 15.4 0.0 0.014 15.4 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF3040) COesterase PF00135.23 EXF85221.1 - 1.8e-90 304.1 0.1 4.2e-82 276.5 0.1 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF85221.1 - 1.6e-12 47.4 0.0 2.6e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF85221.1 - 0.031 14.0 0.0 0.054 13.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sugar_tr PF00083.19 EXF85222.1 - 7.5e-37 126.9 35.9 1.4e-34 119.4 24.9 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF85222.1 - 1.4e-19 70.0 39.8 1.2e-09 37.3 12.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1673 PF07895.6 EXF85222.1 - 2 7.8 5.2 0.92 8.9 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) PhoD PF09423.5 EXF85223.1 - 4.2e-50 170.6 1.4 7.5e-50 169.8 1.0 1.4 1 0 0 1 1 1 1 PhoD-like phosphatase Orexin_rec2 PF03827.8 EXF85224.1 - 0.017 15.1 0.3 0.024 14.6 0.2 1.3 1 0 0 1 1 1 0 Orexin receptor type 2 DUF819 PF05684.7 EXF85224.1 - 0.069 11.9 0.1 0.079 11.7 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF819) Methyltransf_23 PF13489.1 EXF85225.1 - 1.2e-12 47.8 0.0 1.5e-12 47.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF85225.1 - 5.7e-10 39.5 0.0 9.9e-10 38.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF85225.1 - 3.1e-08 33.9 0.0 6e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF85225.1 - 9.8e-07 28.4 0.0 1.7e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF85225.1 - 0.00013 22.2 0.0 0.00027 21.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF85225.1 - 0.00037 21.0 0.0 0.0016 19.0 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF85225.1 - 0.0015 17.7 0.0 0.0069 15.5 0.0 2.0 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.13 EXF85225.1 - 0.0041 16.4 0.0 0.047 12.9 0.0 2.1 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain BMC PF00936.14 EXF85225.1 - 0.0077 15.8 0.5 0.018 14.7 0.0 1.8 2 0 0 2 2 2 1 BMC domain MetW PF07021.7 EXF85225.1 - 0.019 14.3 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_26 PF13659.1 EXF85225.1 - 0.047 13.7 0.1 0.21 11.6 0.1 2.0 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EXF85225.1 - 0.081 12.9 0.3 0.73 9.7 0.2 2.3 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF4171 PF13775.1 EXF85226.1 - 0.019 15.1 2.8 0.021 15.0 1.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4171) TRP PF06011.7 EXF85227.1 - 2.8e-133 444.7 31.1 3.6e-133 444.3 21.6 1.1 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel TRP_N PF14558.1 EXF85227.1 - 5e-36 123.8 0.4 1.2e-35 122.5 0.3 1.7 1 0 0 1 1 1 1 ML-like domain Fungal_trans_2 PF11951.3 EXF85228.1 - 1.1e-17 63.7 9.8 1.6e-16 59.8 6.8 2.2 1 1 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF85228.1 - 8.3e-06 25.6 11.1 1.5e-05 24.8 7.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_45 PF02015.11 EXF85230.1 - 8e-53 179.4 11.6 9.2e-53 179.2 8.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Sfi1 PF08457.5 EXF85231.1 - 4.8e-26 91.3 39.4 8e-17 60.8 4.8 2.9 2 1 0 2 2 2 2 Sfi1 spindle body protein Rav1p_C PF12234.3 EXF85232.1 - 6.6e-235 781.0 0.0 1.3e-224 747.0 0.0 2.6 2 1 1 3 3 3 2 RAVE protein 1 C terminal OPT PF03169.10 EXF85232.1 - 1.7e-128 429.8 20.5 2.3e-128 429.3 14.2 1.1 1 0 0 1 1 1 1 OPT oligopeptide transporter protein WD40 PF00400.27 EXF85232.1 - 0.00011 21.9 0.2 0.039 13.8 0.0 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat Methyltransf_31 PF13847.1 EXF85233.1 - 8.1e-12 44.9 0.1 1.5e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF85233.1 - 9.7e-12 45.2 0.0 2.8e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EXF85233.1 - 8.4e-11 41.5 0.0 1.7e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EXF85233.1 - 3.3e-10 40.5 0.5 2.9e-09 37.4 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF85233.1 - 3e-08 33.7 0.0 5.7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF85233.1 - 2e-06 27.2 0.1 3.3e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EXF85233.1 - 2.1e-06 27.9 0.0 4.4e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF85233.1 - 3.1e-06 26.9 0.0 6.7e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF85233.1 - 4.6e-06 27.0 0.0 1.5e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EXF85233.1 - 0.00076 18.5 0.0 0.0015 17.5 0.0 1.5 1 1 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_16 PF10294.4 EXF85233.1 - 0.001 18.5 0.0 0.0027 17.1 0.0 1.7 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_9 PF08003.6 EXF85233.1 - 0.0031 16.2 0.0 0.0053 15.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) UPF0020 PF01170.13 EXF85233.1 - 0.0042 16.6 0.1 0.011 15.2 0.1 1.6 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 CMAS PF02353.15 EXF85233.1 - 0.01 14.9 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase TehB PF03848.9 EXF85233.1 - 0.017 14.3 0.1 0.032 13.3 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TehB FtsJ PF01728.14 EXF85233.1 - 0.031 14.2 0.0 0.056 13.4 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Ubie_methyltran PF01209.13 EXF85233.1 - 0.032 13.3 0.0 0.051 12.6 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EXF85233.1 - 0.086 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Uso1_p115_head PF04869.9 EXF85234.1 - 1.2e-110 369.1 0.0 3.1e-110 367.8 0.0 1.8 1 0 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.8 EXF85234.1 - 0.00068 19.5 49.0 0.00068 19.5 33.9 4.6 1 1 2 3 3 3 1 Uso1 / p115 like vesicle tethering protein, C terminal region NOA36 PF06524.7 EXF85234.1 - 3.4 6.8 17.4 8.8 5.4 12.0 1.7 1 0 0 1 1 1 0 NOA36 protein XRN_N PF03159.13 EXF85235.1 - 1.6e-107 358.2 0.0 3.9e-107 357.0 0.0 1.7 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus RasGAP PF00616.14 EXF85237.1 - 3.2e-45 154.2 0.1 6.1e-45 153.3 0.1 1.5 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 EXF85237.1 - 1.3e-10 41.3 0.2 2.8e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Transket_pyr PF02779.19 EXF85238.1 - 3e-62 209.2 0.0 5.4e-62 208.4 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EXF85238.1 - 6.4e-55 185.9 0.0 8.8e-55 185.5 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component zf-C2H2 PF00096.21 EXF85239.1 - 1.1e-22 78.8 21.8 2.7e-06 27.3 0.3 4.8 4 0 0 4 4 4 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EXF85239.1 - 1.4e-22 78.8 24.8 7.6e-09 35.4 0.8 5.2 5 0 0 5 5 5 4 Zinc-finger double domain zf-C2H2_4 PF13894.1 EXF85239.1 - 7.1e-17 60.4 22.4 3.8e-05 23.7 0.4 5.1 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.2 EXF85239.1 - 5.9e-05 23.1 10.7 1.4 9.2 0.2 4.8 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EXF85239.1 - 0.00034 20.6 7.7 0.28 11.3 0.1 4.4 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding Zn-ribbon_8 PF09723.5 EXF85239.1 - 2.5 8.1 7.2 13 5.8 0.1 3.9 4 0 0 4 4 4 0 Zinc ribbon domain zf-LYAR PF08790.6 EXF85239.1 - 4.4 7.0 6.8 22 4.8 0.1 3.8 4 0 0 4 4 4 0 LYAR-type C2HC zinc finger CHORD PF04968.7 EXF85239.1 - 9.3 6.5 15.1 5.9 7.2 0.7 3.6 1 1 3 4 4 4 0 CHORD zf-H2C2_5 PF13909.1 EXF85239.1 - 9.3 6.7 9.9 9.7 6.6 0.6 3.7 3 0 0 3 3 3 0 C2H2-type zinc-finger domain Mito_carr PF00153.22 EXF85241.1 - 3.1e-61 203.0 2.7 3.1e-20 71.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Tom7 PF08038.7 EXF85242.1 - 2.3e-18 65.3 0.2 2.7e-18 65.1 0.1 1.1 1 0 0 1 1 1 1 TOM7 family RRM_1 PF00076.17 EXF85243.1 - 2.2e-32 110.4 0.0 3e-15 55.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF85243.1 - 4.4e-20 71.4 0.0 7.6e-11 41.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF85243.1 - 3.2e-16 58.9 0.0 4.3e-08 32.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.6 EXF85243.1 - 0.0011 18.4 0.7 0.11 11.9 0.1 2.4 2 0 0 2 2 2 2 Ribonuclease B OB domain Nup35_RRM_2 PF14605.1 EXF85243.1 - 0.0027 17.4 0.0 0.017 14.8 0.0 2.0 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Pet127 PF08634.5 EXF85244.1 - 2.4e-118 394.2 1.9 3.6e-118 393.6 1.3 1.3 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Cohesin_load PF10345.4 EXF85245.1 - 2e-130 435.8 0.0 2.6e-130 435.5 0.0 1.0 1 0 0 1 1 1 1 Cohesin loading factor DUF1985 PF09331.6 EXF85245.1 - 0.028 14.2 0.1 0.088 12.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1985) TPR_12 PF13424.1 EXF85245.1 - 0.17 11.8 1.6 2.3 8.2 0.4 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Abhydrolase_6 PF12697.2 EXF85246.1 - 3.4e-10 40.2 0.0 5.4e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF85246.1 - 1e-07 31.7 0.0 8.9e-07 28.6 0.0 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF85246.1 - 2.2e-05 24.2 0.0 4.7e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.13 EXF85246.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.4 1 1 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Skp1 PF01466.14 EXF85247.1 - 0.12 12.4 3.4 0.22 11.5 2.4 1.5 1 0 0 1 1 1 0 Skp1 family, dimerisation domain ArgJ PF01960.13 EXF85248.1 - 2.5e-145 483.7 0.1 2.8e-145 483.5 0.1 1.0 1 0 0 1 1 1 1 ArgJ family Acyl-CoA_dh_1 PF00441.19 EXF85249.1 - 5.3e-26 91.5 0.5 8.7e-26 90.8 0.3 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EXF85249.1 - 7.6e-15 54.1 0.0 1.8e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EXF85249.1 - 8.4e-14 51.9 0.9 1.7e-13 50.9 0.6 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EXF85249.1 - 1.2e-13 51.5 0.1 2.5e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Spo12 PF05032.7 EXF85250.1 - 1.4e-14 53.4 0.5 1.4e-14 53.4 0.4 2.1 2 0 0 2 2 2 1 Spo12 family MRP-L51 PF10244.4 EXF85250.1 - 0.063 13.3 0.0 0.15 12.0 0.0 1.7 1 1 0 2 2 2 0 Mitochondrial ribosomal subunit MMR_HSR1 PF01926.18 EXF85251.1 - 2.3e-19 69.4 0.0 5.6e-19 68.2 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.16 EXF85251.1 - 2.4e-19 68.9 0.1 4.2e-19 68.1 0.1 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.13 EXF85251.1 - 1.4e-12 47.1 0.0 2.4e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EXF85251.1 - 3e-05 23.9 0.2 0.021 14.6 0.0 2.5 1 1 1 2 2 2 2 Dynamin family Miro PF08477.8 EXF85251.1 - 0.0029 18.0 0.0 0.0076 16.7 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein ArgK PF03308.11 EXF85251.1 - 0.05 12.3 0.1 0.16 10.6 0.1 1.9 2 0 0 2 2 2 0 ArgK protein DUF2009 PF09418.5 EXF85251.1 - 0.069 11.9 0.1 0.094 11.4 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2009) MCM PF00493.18 EXF85251.1 - 0.089 11.5 0.0 0.18 10.6 0.0 1.4 1 0 0 1 1 1 0 MCM2/3/5 family RRM_1 PF00076.17 EXF85252.1 - 6.9e-08 32.0 0.0 1.2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF85252.1 - 1.9e-07 30.8 0.0 3.9e-07 29.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF85252.1 - 1.6e-05 24.7 0.0 2.9e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EXF85252.1 - 0.0025 17.5 0.0 0.0049 16.6 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCCH PF00642.19 EXF85252.1 - 0.014 15.0 0.7 0.031 13.9 0.5 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Rep_fac_C PF08542.6 EXF85255.1 - 2.1e-19 69.2 0.0 4.6e-19 68.1 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EXF85255.1 - 1.3e-11 44.4 0.0 1.1e-09 38.1 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EXF85255.1 - 2.3e-11 44.0 0.0 4.9e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EXF85255.1 - 2e-07 30.9 0.0 4.1e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EXF85255.1 - 2.2e-06 27.7 0.1 4.5e-05 23.4 0.1 2.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EXF85255.1 - 1.5e-05 25.1 0.1 0.035 14.2 0.0 2.6 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.7 EXF85255.1 - 2.2e-05 23.6 0.0 6.2e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Rad17 PF03215.10 EXF85255.1 - 0.0001 21.1 0.0 0.034 12.8 0.0 2.4 2 1 0 2 2 2 2 Rad17 cell cycle checkpoint protein Viral_helicase1 PF01443.13 EXF85255.1 - 0.00012 21.7 0.0 0.0002 20.9 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.6 EXF85255.1 - 0.00021 20.9 0.0 0.00038 20.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EXF85255.1 - 0.00026 20.5 0.0 0.058 12.8 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain DEAD PF00270.24 EXF85255.1 - 0.0018 17.8 0.1 0.12 11.9 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_25 PF13481.1 EXF85255.1 - 0.002 17.5 0.1 0.066 12.6 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EXF85255.1 - 0.0023 17.6 0.0 0.0051 16.5 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain DNA_pol3_delta PF06144.8 EXF85255.1 - 0.0034 16.9 0.0 0.0058 16.1 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.16 EXF85255.1 - 0.0037 16.4 0.0 0.033 13.3 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.13 EXF85255.1 - 0.0053 16.2 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family NTPase_1 PF03266.10 EXF85255.1 - 0.006 16.3 0.6 0.032 13.9 0.1 2.3 2 1 1 3 3 2 1 NTPase ArgK PF03308.11 EXF85255.1 - 0.0067 15.2 0.1 0.018 13.7 0.0 1.6 1 1 1 2 2 2 1 ArgK protein AAA_11 PF13086.1 EXF85255.1 - 0.0091 15.5 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EXF85255.1 - 0.015 14.5 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.1 EXF85255.1 - 0.022 15.0 0.0 0.045 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_31 PF13614.1 EXF85255.1 - 0.027 14.4 0.0 0.067 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DNA_pol3_gamma3 PF12169.3 EXF85255.1 - 0.03 14.0 0.2 0.56 9.9 0.0 2.7 3 0 0 3 3 3 0 DNA polymerase III subunits gamma and tau domain III AAA_5 PF07728.9 EXF85255.1 - 0.048 13.3 0.1 0.44 10.2 0.1 2.5 3 1 0 3 3 3 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.17 EXF85255.1 - 0.089 11.6 0.0 0.15 10.8 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MMR_HSR1 PF01926.18 EXF85256.1 - 1.8e-17 63.3 0.3 3.7e-15 55.8 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EXF85256.1 - 1.2e-07 31.0 0.5 1.3e-05 24.5 0.1 2.2 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EXF85256.1 - 8.3e-05 21.8 0.0 0.00015 20.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EXF85256.1 - 0.0042 16.2 0.1 0.0076 15.3 0.0 1.4 1 0 0 1 1 1 1 AIG1 family Miro PF08477.8 EXF85256.1 - 0.023 15.1 0.0 0.083 13.3 0.0 2.0 1 0 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 EXF85256.1 - 0.035 13.9 0.4 0.035 13.9 0.3 3.7 3 1 1 4 4 4 0 Dynamin family DUF1510 PF07423.6 EXF85256.1 - 1.8 7.8 13.8 3.3 7.0 9.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 EXF85256.1 - 1.9 6.4 9.8 3.1 5.7 6.8 1.3 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 EXF85256.1 - 2 7.3 7.0 3.6 6.4 4.9 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit LTV PF04180.9 EXF85257.1 - 3.7e-107 359.4 10.8 4.3e-107 359.2 7.5 1.0 1 0 0 1 1 1 1 Low temperature viability protein SAC3_GANP PF03399.11 EXF85258.1 - 3.9e-39 134.3 0.0 6e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EXF85258.1 - 0.0057 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 V_ATPase_I PF01496.14 EXF85258.1 - 1.3 6.7 9.0 0.44 8.3 2.5 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family DUF3609 PF12259.3 EXF85259.1 - 0.057 12.0 0.0 0.11 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3609) Glyco_hydro_43 PF04616.9 EXF85260.1 - 4.6e-24 85.0 0.0 5.3e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 DKCLD PF08068.7 EXF85261.1 - 3.3e-27 94.1 0.1 1.9e-26 91.7 0.0 2.2 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_N PF01509.13 EXF85261.1 - 1.6e-24 86.7 0.2 1.4e-21 77.1 0.1 3.3 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.15 EXF85261.1 - 4.6e-22 77.5 1.0 9.2e-22 76.5 0.7 1.5 1 0 0 1 1 1 1 PUA domain Med19 PF10278.4 EXF85261.1 - 0.42 10.2 7.9 1.1 8.9 5.4 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RNA_polI_A34 PF08208.6 EXF85261.1 - 5 6.7 14.4 8.6 5.9 10.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 SKG6 PF08693.5 EXF85262.1 - 7.9 5.8 9.7 0.95 8.8 3.7 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain CN_hydrolase PF00795.17 EXF85263.1 - 5.7e-12 45.3 0.0 9.6e-12 44.6 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CD99L2 PF12301.3 EXF85265.1 - 0.083 12.5 0.7 8.8 5.9 0.0 2.4 2 0 0 2 2 2 0 CD99 antigen like protein 2 DER1 PF04511.10 EXF85266.1 - 6.8e-26 90.9 4.3 7.9e-26 90.7 3.0 1.0 1 0 0 1 1 1 1 Der1-like family IGPD PF00475.13 EXF85267.1 - 4.7e-60 201.6 0.2 6.7e-60 201.1 0.2 1.2 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase Cut12 PF11500.3 EXF85268.1 - 1e-41 142.1 21.3 1e-41 142.1 14.8 4.8 2 1 3 5 5 5 1 Spindle pole body formation-associated protein FlaC_arch PF05377.6 EXF85268.1 - 0.16 11.8 8.3 2.7 7.9 0.5 3.5 3 1 0 3 3 3 0 Flagella accessory protein C (FlaC) TSC22 PF01166.13 EXF85268.1 - 1.3 9.0 15.4 2.9 7.9 1.5 4.0 2 1 1 3 3 3 0 TSC-22/dip/bun family HGTP_anticodon2 PF12745.2 EXF85269.1 - 2.7e-78 262.8 2.0 2.7e-78 262.8 1.4 2.6 3 0 0 3 3 3 1 Anticodon binding domain of tRNAs Pkinase PF00069.20 EXF85269.1 - 5e-75 252.0 0.0 3.2e-37 128.0 0.0 4.1 3 1 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EXF85269.1 - 2e-49 168.0 0.0 9.9e-21 73.9 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.1 EXF85269.1 - 9.4e-18 64.3 0.0 3.2e-17 62.5 0.0 2.0 1 1 0 1 1 1 1 Histidyl-tRNA synthetase RWD PF05773.17 EXF85269.1 - 7.3e-12 45.1 0.0 2.3e-11 43.5 0.0 1.9 1 0 0 1 1 1 1 RWD domain APH PF01636.18 EXF85269.1 - 2.5e-06 27.3 3.2 0.021 14.5 0.1 3.1 3 0 0 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.1 EXF85269.1 - 5.2e-05 22.3 0.0 0.01 14.8 0.0 2.5 2 0 0 2 2 2 2 Kinase-like HGTP_anticodon PF03129.15 EXF85269.1 - 0.0017 18.2 0.0 0.0066 16.3 0.0 2.1 1 0 0 1 1 1 1 Anticodon binding domain UQ_con PF00179.21 EXF85270.1 - 1.5e-31 108.6 0.0 1.2e-27 96.0 0.0 2.1 1 1 1 2 2 2 2 Ubiquitin-conjugating enzyme RWD PF05773.17 EXF85270.1 - 0.1 12.4 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 RWD domain TGF_beta_GS PF08515.7 EXF85271.1 - 0.29 10.4 3.0 7.7 5.9 0.4 2.6 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif DnaJ PF00226.26 EXF85272.1 - 9.5e-27 92.5 1.9 1.5e-26 91.8 1.3 1.3 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EXF85272.1 - 2.2e-23 81.9 2.7 3e-21 75.0 0.1 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain HAD_2 PF13419.1 EXF85273.1 - 3.7e-19 69.6 0.0 7.2e-19 68.6 0.0 1.4 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EXF85273.1 - 3.7e-10 40.5 0.1 2.1e-09 38.1 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EXF85273.1 - 9.2e-09 34.9 0.1 1.9e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like NIF PF03031.13 EXF85273.1 - 0.0026 17.4 0.0 0.21 11.2 0.0 2.1 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Hydrolase_6 PF13344.1 EXF85273.1 - 0.026 14.3 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Init_tRNA_PT PF04179.7 EXF85274.1 - 1.8e-149 498.4 0.0 2.4e-149 498.0 0.0 1.2 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase MARVEL PF01284.18 EXF85275.1 - 5.5e-06 26.2 9.9 9.7e-06 25.4 6.8 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF4281 PF14108.1 EXF85275.1 - 7.3e-05 22.8 0.4 0.00012 22.1 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) QueT PF06177.6 EXF85275.1 - 0.21 11.5 3.5 0.35 10.8 2.4 1.4 1 1 0 1 1 1 0 QueT transporter Nop16 PF09420.5 EXF85276.1 - 1.4e-45 155.3 9.9 4.4e-41 140.7 1.2 2.2 2 0 0 2 2 2 2 Ribosome biogenesis protein Nop16 Mg_chelatase_2 PF13335.1 EXF85276.1 - 0.045 14.1 0.2 0.39 11.1 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI GFO_IDH_MocA PF01408.17 EXF85277.1 - 1.2e-11 45.1 0.7 5.5e-11 43.0 0.5 2.2 1 1 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.11 EXF85277.1 - 0.027 14.8 0.0 0.054 13.9 0.0 1.5 1 1 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DHDPS PF00701.17 EXF85278.1 - 4.7e-34 117.3 0.0 5.5e-34 117.0 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family DAO PF01266.19 EXF85279.1 - 1e-54 185.8 4.0 2.8e-54 184.4 2.7 1.6 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox PF00070.22 EXF85279.1 - 1.4e-05 25.3 0.1 0.14 12.5 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF85279.1 - 3.8e-05 23.6 0.4 0.00011 22.1 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.9 EXF85279.1 - 0.0026 16.4 0.3 0.0043 15.7 0.2 1.3 1 0 0 1 1 1 1 Tryptophan halogenase GMC_oxred_N PF00732.14 EXF85279.1 - 0.027 13.6 0.2 1.3 8.0 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Thi4 PF01946.12 EXF85279.1 - 0.027 13.5 0.0 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family GSHPx PF00255.14 EXF85280.1 - 1.9e-41 139.7 0.1 2.4e-41 139.4 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.16 EXF85280.1 - 9.3e-05 22.1 0.0 0.00017 21.2 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EXF85280.1 - 0.00014 21.4 0.1 0.00017 21.1 0.0 1.3 1 1 0 1 1 1 1 Redoxin DUF4174 PF13778.1 EXF85280.1 - 0.0035 17.4 0.0 0.0058 16.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4174) Band_7 PF01145.20 EXF85281.1 - 3.7e-31 108.4 0.8 1.6e-30 106.3 0.3 2.0 2 0 0 2 2 2 1 SPFH domain / Band 7 family UQ_con PF00179.21 EXF85281.1 - 3.9e-16 58.7 0.0 6.3e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EXF85281.1 - 0.017 14.9 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 RWD domain Band_7_1 PF13421.1 EXF85281.1 - 0.055 12.9 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family Sec7_N PF12783.2 EXF85282.1 - 5.9e-38 129.9 2.7 2.4e-36 124.6 0.0 3.7 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EXF85282.1 - 2.4e-07 30.1 0.8 5.8e-05 22.5 0.0 3.9 3 0 0 3 3 3 2 Domain of unknown function (DUF1981) Nnf1 PF03980.9 EXF85283.1 - 5.8e-09 35.9 0.6 1e-08 35.1 0.1 1.6 2 0 0 2 2 2 1 Nnf1 TPR_MLP1_2 PF07926.7 EXF85283.1 - 0.0011 18.7 0.1 0.0015 18.3 0.1 1.1 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Reo_sigmaC PF04582.7 EXF85283.1 - 0.028 13.6 0.5 0.031 13.4 0.4 1.0 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Cortex-I_coil PF09304.5 EXF85283.1 - 0.041 13.9 0.3 0.057 13.4 0.2 1.2 1 0 0 1 1 1 0 Cortexillin I, coiled coil Nsp1_C PF05064.8 EXF85283.1 - 0.054 13.1 0.3 0.075 12.6 0.2 1.3 1 0 0 1 1 1 0 Nsp1-like C-terminal region Snapin_Pallidin PF14712.1 EXF85283.1 - 0.061 13.6 0.4 0.067 13.4 0.3 1.2 1 0 0 1 1 1 0 Snapin/Pallidin PH_9 PF15410.1 EXF85284.1 - 3.3e-07 30.4 0.0 5.2e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EXF85284.1 - 4.1e-06 26.9 0.0 6.3e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 PH domain Imm33 PF15580.1 EXF85284.1 - 0.11 11.9 0.2 1.3 8.5 0.1 2.2 1 1 1 2 2 2 0 Immunity protein 33 NTF2 PF02136.15 EXF85285.1 - 7.7e-24 84.3 0.3 1.3e-23 83.6 0.2 1.4 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EXF85285.1 - 2.3e-05 23.9 0.1 3.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF85285.1 - 3.6e-05 23.6 0.0 6.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF85285.1 - 0.0052 16.6 0.0 0.01 15.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EXF85285.1 - 0.006 16.4 1.7 0.017 14.9 0.0 2.5 2 1 0 2 2 2 1 RNA binding motif Sushi_2 PF09014.5 EXF85285.1 - 0.04 13.6 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 Beta-2-glycoprotein-1 fifth domain PAT1 PF09770.4 EXF85285.1 - 1.1 7.3 25.8 1.5 7.0 17.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Phosphodiest PF01663.17 EXF85286.1 - 1.1e-14 54.5 0.2 1.9e-14 53.8 0.1 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EXF85286.1 - 1e-06 28.2 0.0 1.6e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Sulfatase Metalloenzyme PF01676.13 EXF85286.1 - 0.00015 21.2 0.9 0.00024 20.6 0.6 1.2 1 0 0 1 1 1 1 Metalloenzyme superfamily Sugar_tr PF00083.19 EXF85287.1 - 3e-76 256.8 16.2 3.7e-76 256.5 11.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF85287.1 - 2.3e-14 52.8 22.0 2.3e-14 52.8 15.2 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EXF85287.1 - 3.1e-05 22.5 5.6 3.1e-05 22.5 3.9 2.7 3 1 0 3 3 3 2 MFS/sugar transport protein G-patch_2 PF12656.2 EXF85288.1 - 2.9e-17 62.2 0.4 2.9e-17 62.2 0.3 3.0 3 0 0 3 3 3 1 DExH-box splicing factor binding site DUF2852 PF11014.3 EXF85288.1 - 1.3 8.9 5.4 0.36 10.8 1.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) FAD_binding_6 PF00970.19 EXF85289.1 - 3.3e-27 94.4 0.0 5.8e-27 93.7 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EXF85289.1 - 1.4e-25 89.9 0.0 2e-25 89.4 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EXF85289.1 - 0.00018 21.4 0.0 0.019 14.8 0.0 2.2 2 0 0 2 2 2 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EXF85289.1 - 0.0093 15.9 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain LRR_7 PF13504.1 EXF85291.1 - 0.32 11.3 17.1 23 5.7 0.1 6.6 6 0 0 6 6 6 0 Leucine rich repeat LRR_4 PF12799.2 EXF85291.1 - 0.37 10.4 16.1 6.4 6.5 0.2 5.0 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EXF85291.1 - 0.94 9.7 19.3 16 6.0 0.0 7.5 7 2 0 7 7 7 0 Leucine Rich Repeat LRR_6 PF13516.1 EXF85291.1 - 5 7.4 17.0 47 4.5 0.0 6.5 7 0 0 7 7 7 0 Leucine Rich repeat EF-hand_4 PF12763.2 EXF85292.1 - 4.1e-24 84.3 0.0 3e-12 46.1 0.0 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand DUF1720 PF08226.6 EXF85292.1 - 3.8e-08 33.2 233.5 0.0013 18.7 13.9 8.3 6 2 3 9 9 9 6 Domain of unknown function (DUF1720) EF-hand_1 PF00036.27 EXF85292.1 - 0.0019 17.3 0.0 1.5 8.3 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EXF85292.1 - 0.0021 18.1 0.0 1.5 9.0 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EXF85292.1 - 0.011 15.5 0.1 4 7.5 0.0 3.4 3 0 0 3 3 3 0 EF-hand domain SAPS PF04499.10 EXF85293.1 - 6e-17 61.4 2.0 1.1e-16 60.6 0.0 2.1 2 1 0 2 2 2 1 SIT4 phosphatase-associated protein PAH PF02671.16 EXF85293.1 - 0.073 12.6 1.0 0.52 9.9 0.0 2.5 3 0 0 3 3 3 0 Paired amphipathic helix repeat DUF1902 PF08972.6 EXF85293.1 - 0.15 11.6 1.1 6.3 6.4 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1902) Epimerase PF01370.16 EXF85295.1 - 9e-15 54.7 0.0 1.4e-14 54.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EXF85295.1 - 1.5e-12 46.8 0.0 2.6e-12 46.0 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EXF85295.1 - 5.9e-10 39.4 0.0 1.1e-09 38.5 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EXF85295.1 - 3.7e-07 29.3 0.0 6.5e-05 21.9 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein NmrA PF05368.8 EXF85295.1 - 8.7e-07 28.4 0.0 1.4e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EXF85295.1 - 0.01 14.7 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 EXF85295.1 - 0.077 12.9 0.1 0.57 10.0 0.1 2.3 1 1 0 1 1 1 0 short chain dehydrogenase GCFC PF07842.7 EXF85296.1 - 8.4e-67 225.4 3.9 1.6e-66 224.5 2.7 1.4 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein G-patch PF01585.18 EXF85296.1 - 4.7e-16 58.2 2.3 1.5e-15 56.7 1.6 1.9 1 0 0 1 1 1 1 G-patch domain TIP_N PF12457.3 EXF85296.1 - 2.2e-14 53.4 16.0 2.2e-14 53.4 11.1 2.9 3 1 0 3 3 3 1 Tuftelin interacting protein N terminal G-patch_2 PF12656.2 EXF85296.1 - 3.9e-08 33.0 1.1 3.9e-08 33.0 0.8 3.0 4 1 0 4 4 4 1 DExH-box splicing factor binding site DUF4432 PF14486.1 EXF85296.1 - 0.026 13.0 0.1 0.049 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) ATP-synt_E PF05680.7 EXF85296.1 - 1.7 8.6 7.9 5.7 6.9 5.5 1.9 1 0 0 1 1 1 0 ATP synthase E chain Cyt-b5 PF00173.23 EXF85297.1 - 3.8e-16 58.6 0.0 1.1e-15 57.1 0.0 1.9 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain FAD_binding_1 PF00667.15 EXF85297.1 - 1.1e-10 41.3 0.0 3.1e-10 39.8 0.0 1.8 2 0 0 2 2 2 1 FAD binding domain IDO PF01231.13 EXF85297.1 - 4.7e-09 35.1 0.0 5.9e-08 31.5 0.0 2.4 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase NAD_binding_1 PF00175.16 EXF85297.1 - 7.7e-09 36.0 0.0 1.9e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain zf-LITAF-like PF10601.4 EXF85298.1 - 7.1e-23 80.2 2.7 9.3e-23 79.8 1.8 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain DZR PF12773.2 EXF85298.1 - 0.097 12.4 1.0 10 5.9 0.0 2.3 2 0 0 2 2 2 0 Double zinc ribbon zf-H2C2_2 PF13465.1 EXF85298.1 - 0.14 12.5 0.8 7.7 7.0 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double domain Zn-ribbon_8 PF09723.5 EXF85298.1 - 0.56 10.2 3.6 3 7.8 0.1 2.4 2 0 0 2 2 2 0 Zinc ribbon domain zf-HIT PF04438.11 EXF85298.1 - 1.1 9.0 5.0 3.5 7.3 0.1 2.4 2 1 0 2 2 2 0 HIT zinc finger zf-Mss51 PF13824.1 EXF85298.1 - 3.4 7.5 7.4 13 5.7 4.2 2.3 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Zn_Tnp_IS1595 PF12760.2 EXF85298.1 - 5.1 6.9 6.3 9.7 6.0 0.1 2.2 2 0 0 2 2 2 0 Transposase zinc-ribbon domain WD40 PF00400.27 EXF85299.1 - 9.8e-76 247.1 15.2 5.2e-12 45.1 0.2 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EXF85299.1 - 2.5e-10 39.1 4.0 0.00072 17.8 0.1 4.9 3 2 2 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EXF85299.1 - 0.00028 19.7 0.0 0.71 8.5 0.0 3.3 1 1 1 3 3 3 3 Nup133 N terminal like HEAT PF02985.17 EXF85300.1 - 1.3e-07 31.1 1.3 0.63 10.2 0.1 5.4 5 0 0 5 5 5 2 HEAT repeat CLASP_N PF12348.3 EXF85300.1 - 1.4e-06 27.8 0.0 6.9e-05 22.3 0.0 2.3 2 0 0 2 2 2 1 CLASP N terminal HEAT_2 PF13646.1 EXF85300.1 - 1.9e-05 24.8 4.1 0.14 12.4 0.3 3.5 4 0 0 4 4 4 2 HEAT repeats APG6 PF04111.7 EXF85300.1 - 0.0023 17.0 6.9 0.0043 16.1 4.8 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 MAP65_ASE1 PF03999.7 EXF85300.1 - 0.0037 15.9 4.0 0.0073 14.9 2.8 1.4 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Adaptin_N PF01602.15 EXF85300.1 - 0.018 13.3 0.1 1.7 6.8 0.0 2.7 2 1 0 2 2 2 0 Adaptin N terminal region TPR_MLP1_2 PF07926.7 EXF85300.1 - 0.023 14.4 6.6 0.05 13.3 3.2 2.5 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Cnd1 PF12717.2 EXF85300.1 - 0.17 11.6 0.1 0.94 9.3 0.0 2.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF972 PF06156.8 EXF85300.1 - 1.3 9.4 6.2 17 5.8 3.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) HEAT_EZ PF13513.1 EXF85300.1 - 1.5 9.4 7.8 2.4 8.7 0.9 4.0 4 1 2 6 6 6 0 HEAT-like repeat HALZ PF02183.13 EXF85300.1 - 5.1 6.9 7.5 12 5.6 1.5 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper ADIP PF11559.3 EXF85300.1 - 7.2 6.4 14.3 8 6.3 1.9 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding MCC-bdg_PDZ PF10506.4 EXF85300.1 - 9 6.2 11.0 0.89 9.4 2.1 3.2 2 1 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome CorA PF01544.13 EXF85300.1 - 9.5 5.1 8.4 16 4.3 5.8 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Ras PF00071.17 EXF85302.1 - 6.5e-06 25.6 0.0 1.6e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Ras family CBS PF00571.23 EXF85302.1 - 0.11 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 CBS domain EthD PF07110.6 EXF85304.1 - 1.3e-22 80.4 0.1 2.3e-22 79.7 0.0 1.4 1 0 0 1 1 1 1 EthD domain COesterase PF00135.23 EXF85305.1 - 4.7e-69 233.5 0.8 6e-69 233.1 0.5 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF85305.1 - 0.0004 20.0 1.9 0.00071 19.2 0.2 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EXF85305.1 - 0.0031 17.4 0.1 0.0058 16.5 0.1 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF85305.1 - 0.0057 16.4 0.2 0.011 15.4 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Arginase PF00491.16 EXF85306.1 - 2e-86 289.7 0.0 2.3e-86 289.5 0.0 1.0 1 0 0 1 1 1 1 Arginase family AA_permease PF00324.16 EXF85307.1 - 5.1e-114 381.2 37.8 6.8e-114 380.8 26.2 1.1 1 0 0 1 1 1 1 Amino acid permease ApbA_C PF08546.6 EXF85307.1 - 2.2e-32 111.7 0.0 3.9e-32 110.8 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal AA_permease_2 PF13520.1 EXF85307.1 - 1.1e-30 106.5 42.9 1.4e-30 106.1 29.7 1.1 1 0 0 1 1 1 1 Amino acid permease ApbA PF02558.11 EXF85307.1 - 2.6e-26 91.8 0.0 4.2e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA DUF2252 PF10009.4 EXF85307.1 - 0.0011 17.9 0.0 0.0017 17.3 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2252) ThiF PF00899.16 EXF85307.1 - 0.0051 16.6 0.3 0.034 13.9 0.2 2.1 1 1 0 2 2 2 1 ThiF family GFO_IDH_MocA PF01408.17 EXF85307.1 - 0.0099 16.3 0.0 0.02 15.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_7 PF13241.1 EXF85307.1 - 0.027 14.7 0.0 0.064 13.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding IlvN PF07991.7 EXF85307.1 - 0.075 12.3 0.1 0.13 11.6 0.1 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain DAO PF01266.19 EXF85307.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EXF85307.1 - 0.22 10.5 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain IRF-3 PF10401.4 EXF85308.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Interferon-regulatory factor 3 DUF3040 PF11239.3 EXF85309.1 - 0.054 13.5 0.1 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Aldolase_II PF00596.16 EXF85310.1 - 9.7e-46 155.6 0.2 1.3e-45 155.2 0.1 1.2 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain TauD PF02668.11 EXF85311.1 - 1.3e-28 100.4 0.3 1.6e-28 100.0 0.2 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Fungal_trans_2 PF11951.3 EXF85312.1 - 5.1e-52 176.7 4.4 7.4e-52 176.2 3.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Tho2 PF11262.3 EXF85312.1 - 0.019 14.0 0.4 0.031 13.3 0.3 1.2 1 0 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 MFS_1 PF07690.11 EXF85313.1 - 1.1e-30 106.5 26.7 2.5e-29 102.1 17.9 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF85313.1 - 1.5e-10 40.2 14.9 1.5e-10 40.2 10.3 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1_like PF12832.2 EXF85313.1 - 0.0066 16.2 2.5 0.0066 16.2 1.7 2.4 3 0 0 3 3 3 1 MFS_1 like family Beta-lactamase PF00144.19 EXF85314.1 - 3.5e-52 177.4 0.4 4.5e-52 177.1 0.3 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.1 EXF85314.1 - 0.028 13.8 0.1 5.5 6.3 0.0 2.3 1 1 0 2 2 2 0 Beta-lactamase enzyme family SET PF00856.23 EXF85315.1 - 0.00023 21.4 0.0 0.00075 19.8 0.0 1.9 1 0 0 1 1 1 1 SET domain Abhydrolase_5 PF12695.2 EXF85316.1 - 4.8e-06 26.3 0.0 1.6e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EXF85316.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) Methyltransf_23 PF13489.1 EXF85317.1 - 2.3e-20 72.9 0.0 5e-20 71.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF85317.1 - 1.6e-12 47.7 0.0 3.3e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF85317.1 - 9.9e-08 31.7 0.0 4.7e-07 29.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF85317.1 - 1.3e-07 32.1 0.0 1.3e-06 28.8 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF85317.1 - 3.2e-06 27.4 0.0 8.1e-06 26.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF85317.1 - 6.2e-06 26.6 0.0 4e-05 24.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF85317.1 - 0.0015 17.7 0.0 0.0064 15.6 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_4 PF02390.12 EXF85317.1 - 0.0018 17.3 0.0 0.0035 16.4 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 EXF85317.1 - 0.013 15.4 0.0 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 FtsJ-like methyltransferase PrmA PF06325.8 EXF85317.1 - 0.031 13.4 0.0 0.045 12.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 EXF85317.1 - 0.031 13.3 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 EXF85317.1 - 0.045 12.9 0.0 0.069 12.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase MTS PF05175.9 EXF85317.1 - 0.076 12.3 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Glycos_transf_1 PF00534.15 EXF85318.1 - 5.1e-21 74.8 0.0 1.2e-20 73.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EXF85318.1 - 5.6e-09 36.2 0.0 1.4e-08 34.9 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EXF85318.1 - 0.01 16.0 0.0 0.047 13.9 0.0 2.0 3 0 0 3 3 3 0 Glycosyl transferases group 1 Globin PF00042.17 EXF85320.1 - 3.4e-10 40.2 0.0 5.3e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.16 EXF85320.1 - 2.3e-08 34.5 0.0 4.5e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EXF85320.1 - 1.5e-07 31.4 0.0 2.8e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EXF85320.1 - 1e-05 25.4 0.0 3.3e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain Protoglobin PF11563.3 EXF85320.1 - 0.00031 20.4 0.1 0.00053 19.6 0.1 1.4 1 0 0 1 1 1 1 Protoglobin Zn_clus PF00172.13 EXF85321.1 - 1.1e-05 25.2 11.5 2e-05 24.3 8.0 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MAP65_ASE1 PF03999.7 EXF85321.1 - 0.0088 14.7 1.8 0.016 13.8 1.2 1.3 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) SRR1 PF07985.7 EXF85321.1 - 0.044 13.7 0.1 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 SRR1 ketoacyl-synt PF00109.21 EXF85322.1 - 1.2e-75 254.3 0.0 2.6e-75 253.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EXF85322.1 - 2.1e-52 178.4 0.1 4.3e-52 177.4 0.1 1.4 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EXF85322.1 - 7e-46 156.7 0.0 1.1e-45 156.0 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EXF85322.1 - 8.4e-46 155.9 0.0 1.9e-45 154.7 0.0 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EXF85322.1 - 9.7e-39 132.9 0.0 3.3e-38 131.2 0.0 2.1 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EXF85322.1 - 5.7e-29 100.3 0.1 5.7e-29 100.3 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EXF85322.1 - 0.0012 17.8 0.1 0.0024 16.9 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_18 PF12847.2 EXF85322.1 - 0.0078 16.7 0.0 0.034 14.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 EXF85322.1 - 0.026 14.7 0.0 0.071 13.3 0.0 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 EXF85322.1 - 0.097 12.2 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Lipase_GDSL PF00657.17 EXF85323.1 - 3e-12 46.8 0.6 3.9e-12 46.4 0.4 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase CBM_1 PF00734.13 EXF85323.1 - 3.1e-11 42.7 15.9 3.1e-11 42.7 11.0 2.5 3 0 0 3 3 3 1 Fungal cellulose binding domain Acetyltransf_1 PF00583.19 EXF85325.1 - 3.1e-12 46.3 0.0 4.3e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF85325.1 - 1.3e-06 28.4 0.0 1.8e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EXF85325.1 - 6.4e-05 22.8 0.0 7.7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EXF85325.1 - 0.00048 20.2 0.2 0.00059 19.9 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EXF85325.1 - 0.0018 18.4 0.0 0.0021 18.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EXF85325.1 - 0.0026 17.4 0.0 0.0041 16.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EXF85325.1 - 0.0061 16.4 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase NMT PF01233.14 EXF85325.1 - 0.012 15.2 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 EXF85325.1 - 0.024 14.5 0.0 0.032 14.0 0.0 1.4 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_5 PF13444.1 EXF85325.1 - 0.046 14.3 0.2 0.12 12.9 0.0 1.8 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SprA_N PF14349.1 EXF85325.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.3 1 0 0 1 1 1 0 Motility related/secretion protein EFG_II PF14492.1 EXF85325.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 2 0 0 2 2 2 0 Elongation Factor G, domain II Peptidase_M20 PF01546.23 EXF85328.1 - 4.6e-26 91.4 0.0 6.3e-26 91.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EXF85328.1 - 0.0001 21.9 0.0 0.00023 20.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EXF85328.1 - 0.031 14.0 0.0 0.056 13.1 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 DUF3357 PF11837.3 EXF85329.1 - 0.024 14.4 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Autoind_bind PF03472.10 EXF85329.1 - 0.027 13.7 0.0 0.05 12.8 0.0 1.4 1 0 0 1 1 1 0 Autoinducer binding domain Herpes_US9 PF06072.6 EXF85329.1 - 0.04 13.7 0.1 0.081 12.7 0.0 1.5 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 WW PF00397.21 EXF85330.1 - 1.4e-10 40.8 1.1 1.4e-10 40.8 0.7 2.1 2 0 0 2 2 2 1 WW domain Methyltransf_23 PF13489.1 EXF85331.1 - 5e-20 71.8 0.0 7.7e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF85331.1 - 7.6e-08 32.0 0.1 9e-07 28.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF85331.1 - 2.1e-07 31.5 0.1 2.6e-06 27.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF85331.1 - 2.7e-07 30.9 0.0 5.3e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF85331.1 - 1.6e-06 28.5 0.0 1.8e-05 25.1 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF85331.1 - 0.0019 18.5 0.0 0.0038 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EXF85331.1 - 0.0071 15.4 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EXF85331.1 - 0.013 14.8 0.0 0.026 13.9 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 EXF85331.1 - 0.16 11.9 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Peptidase_C23 PF05379.6 EXF85332.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Carlavirus endopeptidase DUF1903 PF08991.5 EXF85333.1 - 0.044 13.9 0.1 0.056 13.6 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) PH_10 PF15411.1 EXF85334.1 - 1.9e-45 153.7 0.2 4e-45 152.7 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain CDC24 PF06395.6 EXF85334.1 - 3e-32 110.5 0.0 6.2e-32 109.4 0.0 1.6 1 0 0 1 1 1 1 CDC24 Calponin RhoGEF PF00621.15 EXF85334.1 - 5.1e-32 111.1 0.0 9.4e-32 110.3 0.0 1.4 1 0 0 1 1 1 1 RhoGEF domain PB1 PF00564.19 EXF85334.1 - 4.2e-08 32.7 0.0 1e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 PB1 domain PH PF00169.24 EXF85334.1 - 0.065 13.4 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 PH domain WD40 PF00400.27 EXF85335.1 - 1.8e-40 135.4 6.6 3.9e-07 29.7 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.2 EXF85335.1 - 2.7e-11 43.0 1.3 4.5e-11 42.2 0.2 2.0 2 0 0 2 2 2 1 F-box-like Nup160 PF11715.3 EXF85335.1 - 3.3e-05 22.2 0.3 0.072 11.2 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 F-box PF00646.28 EXF85335.1 - 0.00025 20.5 0.3 0.00066 19.2 0.0 1.8 2 0 0 2 2 2 1 F-box domain MgtE_N PF03448.12 EXF85335.1 - 0.078 13.2 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 MgtE intracellular N domain Snf7 PF03357.16 EXF85336.1 - 3.4e-44 150.2 14.4 3.9e-44 150.0 10.0 1.1 1 0 0 1 1 1 1 Snf7 CENP-F_leu_zip PF10473.4 EXF85336.1 - 0.0015 18.3 11.0 0.15 11.9 6.5 2.6 2 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 NPV_P10 PF05531.7 EXF85336.1 - 0.0018 18.4 9.1 0.97 9.7 0.1 3.2 2 1 0 2 2 2 2 Nucleopolyhedrovirus P10 protein Sec34 PF04136.10 EXF85336.1 - 0.0073 16.0 4.2 0.44 10.2 1.3 2.1 2 0 0 2 2 2 1 Sec34-like family FliD_C PF07195.7 EXF85336.1 - 0.0089 15.3 4.8 0.56 9.4 0.0 2.3 2 0 0 2 2 2 1 Flagellar hook-associated protein 2 C-terminus Reo_sigmaC PF04582.7 EXF85336.1 - 0.015 14.5 4.7 0.054 12.6 0.5 2.0 1 1 0 2 2 2 0 Reovirus sigma C capsid protein Tropomyosin_1 PF12718.2 EXF85336.1 - 0.036 13.8 0.2 0.036 13.8 0.2 2.5 1 1 0 2 2 2 0 Tropomyosin like TraG-D_C PF12696.2 EXF85336.1 - 0.038 13.8 0.3 0.081 12.7 0.2 1.6 1 0 0 1 1 1 0 TraM recognition site of TraD and TraG AAA_13 PF13166.1 EXF85336.1 - 0.04 12.3 5.1 0.057 11.8 3.5 1.3 1 0 0 1 1 1 0 AAA domain FlxA PF14282.1 EXF85336.1 - 0.042 13.8 12.8 0.048 13.6 7.9 1.8 1 1 1 2 2 2 0 FlxA-like protein Tht1 PF04163.7 EXF85336.1 - 0.046 12.1 3.8 0.054 11.8 2.7 1.1 1 0 0 1 1 1 0 Tht1-like nuclear fusion protein Prefoldin PF02996.12 EXF85336.1 - 0.055 13.1 9.2 2.3 7.8 0.0 3.6 3 1 1 4 4 4 0 Prefoldin subunit DUF342 PF03961.8 EXF85336.1 - 0.056 11.8 9.9 0.15 10.4 2.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Prefoldin_2 PF01920.15 EXF85336.1 - 0.12 12.1 11.4 0.28 10.9 0.0 3.7 2 1 1 3 3 3 0 Prefoldin subunit Mod_r PF07200.8 EXF85336.1 - 0.14 12.0 11.6 0.13 12.1 6.3 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Glutaredoxin PF00462.19 EXF85336.1 - 0.18 11.8 0.6 0.56 10.2 0.1 2.0 1 1 1 2 2 1 0 Glutaredoxin IFT46_B_C PF12317.3 EXF85336.1 - 0.24 10.7 3.2 0.31 10.3 2.2 1.3 1 0 0 1 1 1 0 Intraflagellar transport complex B protein 46 C terminal Atg14 PF10186.4 EXF85336.1 - 0.31 9.9 9.1 0.46 9.3 6.3 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 BLOC1_2 PF10046.4 EXF85336.1 - 0.35 11.0 10.5 0.25 11.5 2.3 2.7 1 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Peptidase_M13 PF01431.16 EXF85336.1 - 0.45 9.6 3.3 0.61 9.2 2.3 1.2 1 0 0 1 1 1 0 Peptidase family M13 FlaC_arch PF05377.6 EXF85336.1 - 0.47 10.3 7.1 1.7 8.6 0.1 3.4 2 1 1 3 3 2 0 Flagella accessory protein C (FlaC) DUF4140 PF13600.1 EXF85336.1 - 0.54 10.7 4.4 7 7.1 0.0 3.2 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Mnd1 PF03962.10 EXF85336.1 - 0.58 9.7 10.6 1.2 8.7 7.3 1.6 1 1 0 1 1 1 0 Mnd1 family DASH_Dam1 PF08653.5 EXF85336.1 - 0.61 9.8 4.2 47 3.8 0.1 3.6 3 0 0 3 3 3 0 DASH complex subunit Dam1 COG2 PF06148.6 EXF85336.1 - 0.71 9.7 7.8 6.4 6.6 3.1 3.0 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 IncA PF04156.9 EXF85336.1 - 0.74 9.3 9.1 0.82 9.2 3.4 2.5 1 1 1 2 2 2 0 IncA protein OmpH PF03938.9 EXF85336.1 - 0.98 9.3 14.8 0.47 10.3 7.2 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) APG6 PF04111.7 EXF85336.1 - 1 8.3 11.2 0.68 8.9 6.7 1.4 1 1 0 1 1 1 0 Autophagy protein Apg6 DUF972 PF06156.8 EXF85336.1 - 1.7 8.9 9.2 17 5.8 3.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TMF_DNA_bd PF12329.3 EXF85336.1 - 1.8 8.4 15.0 0.093 12.5 2.2 3.1 3 1 0 3 3 2 0 TATA element modulatory factor 1 DNA binding DUF4337 PF14235.1 EXF85336.1 - 2.7 7.8 7.5 0.68 9.7 2.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Baculo_PEP_C PF04513.7 EXF85336.1 - 3.3 7.5 9.9 34 4.2 5.5 2.4 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF310 PF03750.8 EXF85336.1 - 5 7.3 7.2 8.2 6.6 4.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF310) DUF4446 PF14584.1 EXF85336.1 - 8 6.2 8.1 14 5.5 2.7 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) PKD_channel PF08016.7 EXF85337.1 - 3.5 5.9 14.8 3 6.1 1.7 2.3 2 0 0 2 2 2 0 Polycystin cation channel DUF1961 PF09224.6 EXF85338.1 - 6e-80 267.4 0.0 7e-80 267.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1961) DUF1080 PF06439.6 EXF85338.1 - 0.024 14.5 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1080) DSPc PF00782.15 EXF85340.1 - 5.3e-13 48.6 0.0 1.2e-05 24.8 0.0 3.3 3 0 0 3 3 3 3 Dual specificity phosphatase, catalytic domain Ribosomal_S27e PF01667.12 EXF85340.1 - 0.018 14.5 0.3 4.4 6.9 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein S27 rRNA_methylase PF06962.7 EXF85340.1 - 0.03 14.0 0.1 0.052 13.2 0.1 1.3 1 0 0 1 1 1 0 Putative rRNA methylase zf-DNA_Pol PF08996.5 EXF85340.1 - 0.16 11.3 1.9 0.65 9.3 1.3 1.9 1 1 0 1 1 1 0 DNA Polymerase alpha zinc finger zf-C2H2_4 PF13894.1 EXF85341.1 - 4.3e-06 26.6 21.3 0.027 14.7 0.8 5.2 4 1 0 4 4 4 4 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF85341.1 - 0.00059 20.0 23.5 0.017 15.4 0.7 5.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EXF85341.1 - 0.0047 17.1 0.2 0.0047 17.1 0.1 4.0 6 0 0 6 6 6 1 Zinc-finger double domain zf-CHCC PF10276.4 EXF85341.1 - 0.11 12.4 3.7 3.5 7.5 0.1 2.7 2 0 0 2 2 2 0 Zinc-finger domain Peroxidase_2 PF01328.12 EXF85342.1 - 2.5e-35 121.6 0.3 3.2e-35 121.3 0.2 1.0 1 0 0 1 1 1 1 Peroxidase, family 2 Peptidase_S9 PF00326.16 EXF85343.1 - 2.1e-15 56.5 0.0 2.4e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EXF85343.1 - 2.4e-08 33.8 0.0 3.2e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EXF85343.1 - 4.6e-07 29.6 0.0 7e-07 29.0 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 EXF85343.1 - 2.9e-05 23.4 0.0 6.4e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.2 EXF85343.1 - 0.00056 19.8 0.0 0.65 9.8 0.0 2.1 1 1 0 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 EXF85343.1 - 0.041 13.3 0.0 0.076 12.4 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) LIP PF03583.9 EXF85343.1 - 0.046 12.9 0.0 6 5.9 0.0 2.1 2 0 0 2 2 2 0 Secretory lipase DUF2424 PF10340.4 EXF85343.1 - 0.11 11.1 0.0 0.18 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) DUF2048 PF09752.4 EXF85343.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Ank_2 PF12796.2 EXF85344.1 - 6e-23 81.0 2.6 8.8e-13 48.4 0.8 3.1 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EXF85344.1 - 1.6e-19 69.8 6.7 2e-07 31.3 0.1 5.3 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF85344.1 - 4.9e-18 64.7 10.3 8e-06 25.9 0.3 4.9 4 1 0 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.25 EXF85344.1 - 2.4e-16 58.6 16.0 0.00035 20.2 0.3 6.0 5 1 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.1 EXF85344.1 - 8.2e-16 56.5 6.8 0.0054 16.8 0.1 5.2 5 0 0 5 5 5 4 Ankyrin repeat F-box-like PF12937.2 EXF85344.1 - 0.0012 18.5 0.0 0.0033 17.0 0.0 1.8 1 1 0 1 1 1 1 F-box-like Glyco_hydro_3 PF00933.16 EXF85345.1 - 9.6e-53 179.0 0.5 1.4e-52 178.5 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF85345.1 - 3.9e-44 150.8 0.1 8.1e-44 149.8 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF85345.1 - 2.1e-26 91.6 0.6 1.4e-24 85.7 0.1 2.4 2 0 0 2 2 2 2 Fibronectin type III-like domain Vfa1 PF08432.5 EXF85346.1 - 6.8e-43 146.7 25.1 7.8e-43 146.6 17.4 1.0 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.9 EXF85346.1 - 0.012 13.7 9.7 0.011 13.8 6.8 1.0 1 0 0 1 1 1 0 CDC45-like protein ORC5_C PF14630.1 EXF85346.1 - 0.019 14.4 0.4 0.023 14.1 0.3 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus Rtf2 PF04641.7 EXF85346.1 - 0.035 13.3 18.7 0.044 12.9 13.0 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF3295 PF11702.3 EXF85346.1 - 0.044 12.7 9.4 0.05 12.5 6.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) DUF1510 PF07423.6 EXF85346.1 - 0.047 13.0 19.5 0.055 12.8 13.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) GAGA_bind PF06217.7 EXF85346.1 - 0.067 13.1 10.1 0.071 13.0 7.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Zip PF02535.17 EXF85346.1 - 0.072 12.0 1.2 0.064 12.2 0.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter FLO_LFY PF01698.11 EXF85346.1 - 0.092 11.5 9.3 0.099 11.4 6.4 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein BTV_NS2 PF04514.7 EXF85346.1 - 0.095 11.5 13.2 0.11 11.3 9.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF2347 PF09804.4 EXF85346.1 - 0.15 11.2 2.0 0.16 11.1 1.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) DUF4220 PF13968.1 EXF85346.1 - 0.19 10.8 3.1 0.2 10.7 2.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) FixO PF02433.10 EXF85346.1 - 0.22 10.8 1.7 0.27 10.5 1.2 1.2 1 0 0 1 1 1 0 Cytochrome C oxidase, mono-heme subunit/FixO DDHD PF02862.12 EXF85346.1 - 0.23 11.2 7.4 0.27 10.9 5.2 1.1 1 0 0 1 1 1 0 DDHD domain BORG_CEP PF14957.1 EXF85346.1 - 0.31 11.9 5.8 0.43 11.5 4.1 1.2 1 0 0 1 1 1 0 Cdc42 effector Hid1 PF12722.2 EXF85346.1 - 0.32 8.6 3.6 0.32 8.6 2.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF913 PF06025.7 EXF85346.1 - 0.33 9.6 3.8 0.35 9.5 2.6 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Astro_capsid PF03115.9 EXF85346.1 - 0.34 9.1 3.9 0.34 9.1 2.7 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor TraH_2 PF06871.6 EXF85346.1 - 0.35 10.2 3.3 0.45 9.9 2.3 1.1 1 0 0 1 1 1 0 TraH_2 CT47 PF15623.1 EXF85346.1 - 0.41 10.3 14.5 0.4 10.3 10.1 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 DUF2413 PF10310.4 EXF85346.1 - 0.46 9.2 14.8 0.53 9.0 10.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) NPR3 PF03666.8 EXF85346.1 - 0.68 8.4 11.3 0.76 8.2 7.8 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4407 PF14362.1 EXF85346.1 - 0.78 8.6 9.0 1 8.2 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_11 PF13086.1 EXF85346.1 - 0.8 9.2 6.6 0.87 9.1 4.6 1.1 1 0 0 1 1 1 0 AAA domain DUF2722 PF10846.3 EXF85346.1 - 1 8.3 13.1 1.2 8.0 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) U79_P34 PF03064.11 EXF85346.1 - 1 8.8 18.5 1.2 8.6 12.3 1.4 2 0 0 2 2 2 0 HSV U79 / HCMV P34 Ycf1 PF05758.7 EXF85346.1 - 1.3 6.6 16.1 1.6 6.3 11.1 1.0 1 0 0 1 1 1 0 Ycf1 Serinc PF03348.10 EXF85346.1 - 1.6 7.3 3.2 1.7 7.2 2.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Selenoprotein_S PF06936.6 EXF85346.1 - 2 7.9 13.8 2.6 7.5 9.5 1.1 1 0 0 1 1 1 0 Selenoprotein S (SelS) PPP4R2 PF09184.6 EXF85346.1 - 2.1 7.8 20.0 2.4 7.6 13.8 1.1 1 0 0 1 1 1 0 PPP4R2 RNase_H2-Ydr279 PF09468.5 EXF85346.1 - 2.2 7.4 16.7 2.6 7.1 11.6 1.2 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) POX PF07526.6 EXF85346.1 - 3.4 7.8 12.0 4.8 7.3 8.3 1.2 1 0 0 1 1 1 0 Associated with HOX Peroxin-13_N PF04088.8 EXF85346.1 - 3.6 7.5 5.0 5.7 6.8 3.5 1.4 1 0 0 1 1 1 0 Peroxin 13, N-terminal region RNA_pol_3_Rpc31 PF11705.3 EXF85346.1 - 4.3 7.2 20.0 5.3 6.9 13.8 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 MIP-T3 PF10243.4 EXF85346.1 - 4.7 5.5 30.0 5.8 5.2 20.8 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Pox_Ag35 PF03286.9 EXF85346.1 - 4.8 6.6 21.4 6.7 6.1 14.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF1168 PF06658.7 EXF85346.1 - 4.9 6.6 29.0 6.7 6.2 20.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Paramyxo_ncap PF00973.14 EXF85346.1 - 8.5 4.9 8.9 10 4.6 6.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein NARP1 PF12569.3 EXF85346.1 - 8.7 4.9 23.4 11 4.6 16.2 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 RNA_polI_A34 PF08208.6 EXF85346.1 - 8.9 5.9 31.2 12 5.4 21.6 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Peptidase_S49_N PF08496.5 EXF85346.1 - 9.4 6.0 17.7 15 5.3 12.3 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Rtt106 PF08512.7 EXF85347.1 - 2e-24 85.4 0.0 3.3e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like Cwf_Cwc_15 PF04889.7 EXF85347.1 - 3.9 7.1 21.4 6 6.4 14.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Amino_oxidase PF01593.19 EXF85348.1 - 5.4e-58 197.1 0.0 6.3e-58 196.9 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EXF85348.1 - 5.2e-14 52.0 0.2 1.1e-13 50.9 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF85348.1 - 9.8e-10 37.8 0.0 7.7e-07 28.3 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF85348.1 - 5e-06 25.6 0.1 8.8e-06 24.8 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EXF85348.1 - 5.8e-06 26.6 0.1 1.2e-05 25.5 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF85348.1 - 2.3e-05 23.6 0.1 3.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EXF85348.1 - 6.5e-05 22.1 0.1 0.0001 21.5 0.1 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EXF85348.1 - 8.8e-05 22.6 0.0 0.00039 20.5 0.1 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF85348.1 - 0.0001 20.8 0.2 0.00016 20.2 0.2 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.14 EXF85348.1 - 0.00014 21.0 0.1 0.00022 20.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EXF85348.1 - 0.0015 18.4 0.0 0.0028 17.5 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GDI PF00996.13 EXF85348.1 - 0.0053 15.1 0.0 0.027 12.7 0.0 2.1 3 0 0 3 3 3 1 GDP dissociation inhibitor GIDA PF01134.17 EXF85348.1 - 0.011 14.6 0.2 0.017 14.0 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.16 EXF85348.1 - 0.042 13.4 0.0 0.073 12.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EXF85348.1 - 0.12 11.2 0.3 0.19 10.5 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein p450 PF00067.17 EXF85353.1 - 9.4e-27 93.6 0.0 2.1e-25 89.1 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 DUF607 PF04678.8 EXF85354.1 - 1.1e-38 132.9 0.2 1.1e-38 132.9 0.1 2.4 3 1 0 3 3 3 1 Protein of unknown function, DUF607 Acetyltransf_8 PF13523.1 EXF85355.1 - 5.9e-37 126.8 0.0 9e-37 126.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain CLN3 PF02487.12 EXF85356.1 - 1.4e-106 356.7 14.6 3.8e-99 332.2 4.2 2.2 1 1 1 2 2 2 2 CLN3 protein MFS_1 PF07690.11 EXF85356.1 - 0.017 13.8 25.3 0.019 13.7 5.3 2.5 1 1 1 2 2 2 0 Major Facilitator Superfamily DUF1674 PF07896.7 EXF85358.1 - 0.048 13.8 0.1 0.079 13.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1674) GMC_oxred_N PF00732.14 EXF85359.1 - 1.2e-62 211.7 0.2 1.5e-62 211.3 0.1 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF85359.1 - 8.4e-31 107.2 0.0 1.8e-30 106.1 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EXF85359.1 - 9.6e-05 21.4 3.6 0.0017 17.3 0.9 2.7 3 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF85359.1 - 0.00011 22.1 0.1 0.00047 20.1 0.0 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EXF85359.1 - 0.00016 21.8 0.8 0.024 14.6 0.2 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF85359.1 - 0.00077 18.4 0.9 0.0012 17.8 0.1 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_2 PF00890.19 EXF85359.1 - 0.0018 17.1 0.8 0.012 14.4 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EXF85359.1 - 0.0086 15.1 0.1 0.021 13.9 0.1 1.6 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EXF85359.1 - 0.012 15.4 0.6 0.11 12.3 0.2 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF85359.1 - 0.014 13.9 0.3 0.085 11.3 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein NAD_binding_9 PF13454.1 EXF85359.1 - 0.027 14.2 0.3 0.17 11.6 0.1 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EXF85359.1 - 0.068 13.5 0.5 0.91 9.9 0.2 2.7 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ADH_N PF08240.7 EXF85360.1 - 4.8e-08 32.7 0.1 8.6e-07 28.6 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF85360.1 - 8.3e-05 22.1 0.0 0.00024 20.6 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ABC2_membrane PF01061.19 EXF85361.1 - 2.6e-87 291.3 66.2 4.7e-45 153.3 13.1 3.7 4 0 0 4 4 4 2 ABC-2 type transporter PDR_CDR PF06422.7 EXF85361.1 - 6.7e-39 131.7 2.5 2.5e-31 107.3 0.1 2.8 2 0 0 2 2 2 2 CDR ABC transporter ABC_tran PF00005.22 EXF85361.1 - 1.4e-37 129.0 0.1 3e-17 63.1 0.0 2.8 3 0 0 3 3 2 2 ABC transporter ABC_trans_N PF14510.1 EXF85361.1 - 8.4e-22 77.0 0.0 2.3e-21 75.6 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal AAA_25 PF13481.1 EXF85361.1 - 2e-09 37.1 0.7 1e-05 25.0 0.0 3.3 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.1 EXF85361.1 - 1.7e-06 28.1 2.1 0.00019 21.4 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain DUF258 PF03193.11 EXF85361.1 - 3.1e-05 23.2 0.0 0.005 16.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 EXF85361.1 - 3.7e-05 23.6 0.1 0.0027 17.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain cobW PF02492.14 EXF85361.1 - 0.00025 20.5 3.3 0.0016 17.9 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.1 EXF85361.1 - 0.0016 17.9 2.6 0.035 13.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.1 EXF85361.1 - 0.0032 17.7 0.2 0.071 13.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EXF85361.1 - 0.0065 17.2 0.0 0.15 12.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EXF85361.1 - 0.0069 16.5 0.8 0.74 9.9 0.1 2.8 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.14 EXF85361.1 - 0.017 14.3 0.0 4.1 6.5 0.0 3.2 3 1 0 3 3 3 0 RecF/RecN/SMC N terminal domain NACHT PF05729.7 EXF85361.1 - 0.034 13.8 1.9 1.7 8.2 0.1 2.6 2 0 0 2 2 2 0 NACHT domain Miro PF08477.8 EXF85361.1 - 0.038 14.4 0.1 16 6.0 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA_30 PF13604.1 EXF85361.1 - 0.075 12.5 0.1 3.2 7.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EXF85361.1 - 0.077 12.9 0.0 8.9 6.3 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EXF85361.1 - 0.1 12.3 0.0 7.4 6.1 0.0 2.2 2 0 0 2 2 2 0 Archaeal ATPase AAA_21 PF13304.1 EXF85361.1 - 0.11 12.4 0.0 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EXF85361.1 - 0.14 11.8 1.5 7 6.4 0.1 2.8 2 0 0 2 2 2 0 Part of AAA domain AAA_10 PF12846.2 EXF85361.1 - 0.32 10.3 1.5 16 4.7 0.0 3.1 3 0 0 3 3 3 0 AAA-like domain MFS_1 PF07690.11 EXF85362.1 - 1.1e-42 146.0 63.3 3.4e-40 137.8 32.5 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF85362.1 - 7.7e-06 24.7 15.4 7.7e-06 24.7 10.7 2.8 3 0 0 3 3 3 2 Sugar (and other) transporter TRI5 PF06330.6 EXF85363.1 - 2.4e-06 26.4 0.0 3e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 Trichodiene synthase (TRI5) Cyto_heme_lyase PF01265.12 EXF85364.1 - 1.3e-85 287.1 13.1 1.1e-82 277.5 1.1 2.1 1 1 1 2 2 2 2 Cytochrome c/c1 heme lyase DUF2638 PF10937.3 EXF85365.1 - 4.2e-34 117.9 1.3 5.4e-34 117.5 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2638) DUF647 PF04884.9 EXF85366.1 - 2.6e-89 298.7 3.5 2.7e-89 298.6 1.5 1.6 2 0 0 2 2 2 1 Vitamin B6 photo-protection and homoeostasis GHMP_kinases_N PF00288.21 EXF85367.1 - 1.3e-10 41.1 2.1 4.5e-10 39.4 0.5 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain Lsm_interact PF05391.6 EXF85368.1 - 0.4 10.1 2.7 0.42 10.1 0.6 2.1 2 0 0 2 2 2 0 Lsm interaction motif Abhydrolase_6 PF12697.2 EXF85369.1 - 7.2e-14 52.2 2.5 7.8e-14 52.1 0.3 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF85369.1 - 3.3e-10 39.8 0.2 1.7e-09 37.6 0.1 2.2 2 1 0 2 2 2 1 Alpha/beta hydrolase family DUF1100 PF06500.6 EXF85369.1 - 0.0004 19.0 0.0 0.00075 18.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1100) Peptidase_S15 PF02129.13 EXF85369.1 - 0.00098 18.6 0.0 0.0033 16.9 0.0 1.8 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) BAAT_C PF08840.6 EXF85369.1 - 0.0019 17.9 0.0 0.0051 16.5 0.0 1.6 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 EXF85369.1 - 0.011 15.2 0.0 0.78 9.2 0.0 2.4 1 1 0 2 2 2 0 alpha/beta hydrolase fold DLH PF01738.13 EXF85369.1 - 0.019 14.2 0.3 1.5 8.0 0.0 2.5 1 1 1 2 2 2 0 Dienelactone hydrolase family PhoPQ_related PF10142.4 EXF85369.1 - 0.021 13.3 0.0 0.041 12.3 0.0 1.4 1 1 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein AXE1 PF05448.7 EXF85369.1 - 0.024 13.1 0.3 0.3 9.5 0.0 2.5 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) SnoaL_4 PF13577.1 EXF85370.1 - 9e-14 51.4 0.0 1.2e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain PHO4 PF01384.15 EXF85371.1 - 1.1e-109 366.0 16.5 1.3e-109 365.7 11.4 1.1 1 0 0 1 1 1 1 Phosphate transporter family HET PF06985.6 EXF85372.1 - 3e-31 108.4 0.0 6.8e-31 107.2 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) DUF3112 PF11309.3 EXF85373.1 - 9e-26 90.5 7.9 5.6e-25 88.0 0.7 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3112) Acetyltransf_1 PF00583.19 EXF85374.1 - 7.7e-07 29.0 0.0 1.3e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF85374.1 - 0.0002 21.4 0.0 0.00036 20.6 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EXF85374.1 - 0.0025 17.9 0.0 0.021 14.9 0.0 2.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EXF85374.1 - 0.017 14.9 0.1 0.31 10.9 0.0 2.4 2 2 0 2 2 2 0 Acetyltransferase (GNAT) domain Rep_fac_C PF08542.6 EXF85375.1 - 8.3e-16 57.7 0.1 2.2e-15 56.3 0.0 1.8 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.24 EXF85375.1 - 2.4e-15 56.9 0.0 4.7e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.1 EXF85375.1 - 1.2e-12 47.7 0.0 5.6e-12 45.6 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EXF85375.1 - 2.7e-09 36.2 0.0 3.8e-07 29.1 0.0 2.5 1 1 1 3 3 3 1 Rad17 cell cycle checkpoint protein AAA_19 PF13245.1 EXF85375.1 - 7.3e-07 28.8 0.0 5.8e-06 25.9 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_22 PF13401.1 EXF85375.1 - 8.8e-07 29.1 0.2 9.8e-06 25.7 0.1 2.5 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EXF85375.1 - 2.3e-06 27.7 0.1 9.3e-05 22.4 0.0 2.9 1 1 1 3 3 3 1 AAA ATPase domain AAA_30 PF13604.1 EXF85375.1 - 3.7e-06 26.6 0.0 8e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EXF85375.1 - 2.6e-05 23.8 0.1 8.3e-05 22.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EXF85375.1 - 3.2e-05 23.0 0.1 0.00018 20.6 0.0 2.1 2 1 1 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EXF85375.1 - 5.9e-05 22.9 0.0 0.00014 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.8 EXF85375.1 - 6.4e-05 21.9 0.0 0.00011 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EXF85375.1 - 0.0001 22.0 0.1 0.0004 20.1 0.1 2.1 1 1 1 2 2 2 1 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.8 EXF85375.1 - 0.00011 21.7 0.1 0.00021 20.8 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit TIP49 PF06068.8 EXF85375.1 - 0.00012 20.8 0.0 0.35 9.5 0.0 2.2 2 0 0 2 2 2 2 TIP49 C-terminus AAA_3 PF07726.6 EXF85375.1 - 0.00027 20.5 0.1 0.0018 17.8 0.1 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EXF85375.1 - 0.00065 19.2 0.0 0.0013 18.2 0.0 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain PhoH PF02562.11 EXF85375.1 - 0.0013 18.0 0.0 0.84 8.8 0.0 2.7 3 0 0 3 3 3 1 PhoH-like protein AAA_24 PF13479.1 EXF85375.1 - 0.0013 18.3 0.1 0.0027 17.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EXF85375.1 - 0.0016 17.6 0.0 0.0067 15.6 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EXF85375.1 - 0.0072 15.3 0.0 0.011 14.7 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_28 PF13521.1 EXF85375.1 - 0.0072 16.2 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EXF85375.1 - 0.0075 15.9 0.0 0.34 10.5 0.0 2.1 1 1 0 2 2 2 1 Archaeal ATPase AAA_18 PF13238.1 EXF85375.1 - 0.013 15.8 0.0 0.036 14.3 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.1 EXF85375.1 - 0.013 14.8 0.0 0.033 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EXF85375.1 - 0.019 15.8 0.0 0.061 14.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EXF85375.1 - 0.019 14.3 0.0 0.37 10.1 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_10 PF12846.2 EXF85375.1 - 0.041 13.3 0.1 1.8 7.9 0.0 2.3 1 1 1 2 2 2 0 AAA-like domain ResIII PF04851.10 EXF85375.1 - 0.045 13.5 0.0 0.18 11.5 0.0 1.8 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit RNA_helicase PF00910.17 EXF85375.1 - 0.053 13.7 0.0 0.14 12.3 0.0 1.8 1 1 0 1 1 1 0 RNA helicase DEAD PF00270.24 EXF85375.1 - 0.055 12.9 0.0 1.1 8.7 0.0 2.3 1 1 1 2 2 2 0 DEAD/DEAH box helicase FtsK_SpoIIIE PF01580.13 EXF85375.1 - 0.065 12.6 0.0 0.26 10.7 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family TAFII28 PF04719.9 EXF85375.1 - 0.097 12.4 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 hTAFII28-like protein conserved region SNF2_N PF00176.18 EXF85375.1 - 0.12 11.0 0.0 3 6.5 0.0 2.2 2 0 0 2 2 2 0 SNF2 family N-terminal domain Fringe PF02434.11 EXF85376.1 - 8.7e-06 25.1 1.9 0.0001 21.6 1.3 2.2 1 1 0 1 1 1 1 Fringe-like Galactosyl_T PF01762.16 EXF85376.1 - 0.022 14.3 0.1 0.082 12.5 0.1 1.8 1 1 1 2 2 2 0 Galactosyltransferase PAN_2 PF08276.6 EXF85376.1 - 0.025 14.3 0.5 0.063 13.1 0.3 1.6 1 0 0 1 1 1 0 PAN-like domain PAN_3 PF08277.7 EXF85376.1 - 0.091 12.3 0.1 0.19 11.3 0.1 1.5 1 0 0 1 1 1 0 PAN-like domain PAN_4 PF14295.1 EXF85376.1 - 0.39 10.4 6.3 0.054 13.2 0.9 2.1 2 0 0 2 2 2 0 PAN domain 2OG-FeII_Oxy PF03171.15 EXF85377.1 - 2.1e-05 24.7 0.1 3.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EXF85377.1 - 0.00013 22.3 0.1 0.00022 21.6 0.1 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Peptidase_M24 PF00557.19 EXF85378.1 - 1.5e-38 132.5 0.0 5e-38 130.7 0.0 1.8 1 1 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EXF85378.1 - 0.0002 21.8 0.0 0.00056 20.4 0.0 1.8 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Sugar_tr PF00083.19 EXF85379.1 - 1.9e-33 115.7 33.0 1.1e-30 106.6 22.9 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF85379.1 - 4.8e-25 88.0 43.4 1.8e-14 53.2 7.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EXF85379.1 - 4e-09 35.3 25.9 4.7e-07 28.5 4.3 2.2 1 1 1 2 2 2 2 MFS/sugar transport protein Peptidase_S8 PF00082.17 EXF85380.1 - 2.2e-38 132.0 3.9 2.6e-38 131.8 2.7 1.1 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EXF85380.1 - 9.2e-09 35.7 0.0 2.1e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Peptidase inhibitor I9 OPT PF03169.10 EXF85381.1 - 6.7e-125 417.9 39.3 7.7e-125 417.7 27.3 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF2207 PF09972.4 EXF85381.1 - 0.058 11.9 0.1 0.058 11.9 0.1 2.2 4 0 0 4 4 4 0 Predicted membrane protein (DUF2207) DUF4181 PF13789.1 EXF85381.1 - 0.64 9.9 5.8 2.5 8.0 0.2 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4181) DUF3093 PF11292.3 EXF85381.1 - 3.7 7.3 8.5 0.91 9.3 3.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) Mannosyl_trans3 PF11051.3 EXF85382.1 - 7e-44 150.2 0.0 9.8e-44 149.7 0.0 1.2 1 0 0 1 1 1 1 Mannosyltransferase putative DUF3317 PF11779.3 EXF85382.1 - 0.14 11.5 0.8 0.31 10.5 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) Lipase_2 PF01674.13 EXF85383.1 - 0.11 11.7 0.0 0.37 10.0 0.0 1.9 1 1 0 1 1 1 0 Lipase (class 2) Fungal_trans_2 PF11951.3 EXF85384.1 - 0.0027 16.3 0.1 0.0057 15.3 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain ketoacyl-synt PF00109.21 EXF85385.1 - 2e-75 253.5 0.0 4.5e-75 252.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EXF85385.1 - 1.2e-63 215.3 0.0 2.1e-63 214.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EXF85385.1 - 2.6e-60 203.1 3.5 4.9e-60 202.2 0.7 2.7 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 EXF85385.1 - 6.3e-48 162.8 1.1 6.3e-48 162.8 0.8 2.3 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 EXF85385.1 - 1.1e-45 156.0 0.0 2e-45 155.2 0.0 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EXF85385.1 - 3.7e-43 146.1 0.1 7.8e-42 141.8 0.0 3.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EXF85385.1 - 1.8e-16 59.8 0.0 2.9e-15 55.9 0.0 2.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF85385.1 - 1.2e-08 34.6 0.0 3.5e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EXF85385.1 - 9e-07 29.8 0.0 6e-06 27.1 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EXF85385.1 - 0.00035 20.7 0.3 0.0008 19.6 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Polysacc_synt_2 PF02719.10 EXF85385.1 - 0.074 11.9 0.0 0.14 11.0 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein FSH1 PF03959.8 EXF85387.1 - 2.5e-32 112.0 0.0 6.2e-32 110.7 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EXF85387.1 - 0.1 12.3 0.0 0.19 11.4 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family ABC_membrane PF00664.18 EXF85388.1 - 1.5e-71 240.9 46.2 1e-44 153.0 9.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EXF85388.1 - 7.2e-63 210.9 0.0 1.4e-32 112.8 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EXF85388.1 - 1.3e-15 57.2 5.7 0.00013 21.3 0.1 4.2 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EXF85388.1 - 7.5e-14 52.3 3.5 0.00016 21.7 0.2 4.7 3 2 0 3 3 2 2 AAA domain ABC_ATPase PF09818.4 EXF85388.1 - 9.4e-11 40.9 1.8 0.00048 18.8 0.1 4.0 4 0 0 4 4 4 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EXF85388.1 - 1.5e-09 37.2 0.9 0.00035 20.0 0.1 2.9 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_17 PF13207.1 EXF85388.1 - 6.8e-09 36.5 0.0 0.0025 18.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.1 EXF85388.1 - 2.1e-07 31.4 0.6 0.019 15.3 0.2 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EXF85388.1 - 2.5e-07 30.8 0.8 0.0035 17.3 0.1 2.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EXF85388.1 - 3.1e-07 30.5 3.4 0.06 13.4 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EXF85388.1 - 5e-07 29.3 1.4 0.045 13.1 0.0 3.6 4 0 0 4 4 4 2 AAA domain DUF258 PF03193.11 EXF85388.1 - 2e-06 27.0 0.0 0.038 13.1 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_18 PF13238.1 EXF85388.1 - 7e-06 26.3 0.0 0.086 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EXF85388.1 - 9.6e-06 25.2 0.0 0.16 11.7 0.0 3.0 2 0 0 2 2 2 2 Part of AAA domain AAA_30 PF13604.1 EXF85388.1 - 1.5e-05 24.7 0.5 0.22 11.0 0.0 3.8 4 0 0 4 4 4 2 AAA domain AAA_10 PF12846.2 EXF85388.1 - 6.2e-05 22.5 0.8 0.68 9.3 0.0 3.8 4 0 0 4 4 4 2 AAA-like domain SbcCD_C PF13558.1 EXF85388.1 - 8e-05 22.4 1.3 0.42 10.5 0.1 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit MobB PF03205.9 EXF85388.1 - 0.00011 21.9 0.1 0.36 10.5 0.0 2.5 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EXF85388.1 - 0.0005 19.9 0.1 1.4 8.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_15 PF13175.1 EXF85388.1 - 0.0007 18.7 0.1 0.072 12.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain ATP_bind_1 PF03029.12 EXF85388.1 - 0.0015 18.0 0.1 2.1 7.8 0.0 2.4 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein AAA_5 PF07728.9 EXF85388.1 - 0.0017 18.0 0.0 2 8.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EXF85388.1 - 0.0025 18.0 3.6 23 5.1 0.0 4.4 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EXF85388.1 - 0.0036 17.2 0.1 6.8 6.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain ATP-synt_ab PF00006.20 EXF85388.1 - 0.0049 16.3 0.0 3.8 6.9 0.0 2.8 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain SRP54 PF00448.17 EXF85388.1 - 0.0064 15.9 1.0 2 7.8 0.0 2.7 3 0 0 3 3 2 1 SRP54-type protein, GTPase domain AAA_28 PF13521.1 EXF85388.1 - 0.0084 16.0 0.4 1.7 8.5 0.1 2.5 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EXF85388.1 - 0.013 14.6 1.0 0.72 8.9 0.1 2.6 3 0 0 3 3 2 0 KaiC NB-ARC PF00931.17 EXF85388.1 - 0.013 14.3 0.1 4.5 6.0 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain DUF87 PF01935.12 EXF85388.1 - 0.017 14.9 0.7 2 8.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function DUF87 NACHT PF05729.7 EXF85388.1 - 0.022 14.4 0.2 3.5 7.2 0.0 2.5 2 0 0 2 2 2 0 NACHT domain DUF3987 PF13148.1 EXF85388.1 - 0.022 13.3 0.0 4.2 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Rad17 PF03215.10 EXF85388.1 - 0.043 12.4 0.0 5.4 5.5 0.0 2.1 2 0 0 2 2 2 0 Rad17 cell cycle checkpoint protein FtsK_SpoIIIE PF01580.13 EXF85388.1 - 0.073 12.5 0.4 15 4.9 0.0 3.3 3 0 0 3 3 3 0 FtsK/SpoIIIE family APS_kinase PF01583.15 EXF85388.1 - 0.079 12.6 0.1 14 5.3 0.0 2.4 2 0 0 2 2 2 0 Adenylylsulphate kinase IstB_IS21 PF01695.12 EXF85388.1 - 0.083 12.2 0.6 9.5 5.5 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein MMR_HSR1 PF01926.18 EXF85388.1 - 0.085 12.8 0.6 18 5.2 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_24 PF13479.1 EXF85388.1 - 0.1 12.1 0.8 3 7.3 0.0 2.3 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.10 EXF85388.1 - 0.24 11.1 1.5 29 4.3 0.0 3.6 4 0 0 4 4 4 0 NTPase PIG-P PF08510.7 EXF85388.1 - 1.2 8.7 9.3 0.49 10.0 3.2 2.7 2 1 0 2 2 1 0 PIG-P Cyt-b5 PF00173.23 EXF85389.1 - 2.2e-15 56.1 0.0 1.8e-14 53.2 0.0 2.4 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain IDO PF01231.13 EXF85389.1 - 6.9e-11 41.2 0.0 8.8e-10 37.5 0.0 2.1 2 0 0 2 2 2 1 Indoleamine 2,3-dioxygenase FAD_binding_1 PF00667.15 EXF85389.1 - 4.4e-10 39.3 0.0 2.9e-09 36.7 0.0 2.3 2 1 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.16 EXF85389.1 - 1e-09 38.9 0.0 3e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Aldedh PF00171.17 EXF85391.1 - 2.6e-158 527.1 0.1 3.2e-158 526.8 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GMC_oxred_N PF00732.14 EXF85392.1 - 2.1e-54 184.7 0.0 2.6e-54 184.4 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF85392.1 - 1.7e-37 128.9 0.0 2.5e-37 128.3 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EXF85392.1 - 3.8e-07 29.3 0.1 0.0042 15.9 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EXF85392.1 - 5.2e-07 28.9 0.0 0.00018 20.5 0.0 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF85392.1 - 1.9e-05 23.7 0.0 2.8e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EXF85392.1 - 3.3e-05 23.8 0.1 0.00033 20.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF85392.1 - 0.0032 17.3 0.0 0.057 13.2 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EXF85392.1 - 0.015 13.9 0.0 0.022 13.3 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase Pyr_redox_3 PF13738.1 EXF85392.1 - 0.017 15.1 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF85392.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.17 EXF85392.1 - 0.24 10.2 0.2 6 5.6 0.0 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Pectinesterase PF01095.14 EXF85393.1 - 2e-40 138.2 9.4 3.4e-40 137.4 6.5 1.3 1 0 0 1 1 1 1 Pectinesterase Pec_lyase_C PF00544.14 EXF85393.1 - 5.1e-27 94.6 7.6 1.1e-26 93.5 5.2 1.6 1 0 0 1 1 1 1 Pectate lyase DUF3857 PF12969.2 EXF85393.1 - 1 8.9 4.9 0.86 9.1 0.2 2.3 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3857) MFS_1 PF07690.11 EXF85394.1 - 1.2e-18 66.9 40.5 1.2e-10 40.6 16.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily HNH_2 PF13391.1 EXF85395.1 - 0.0033 17.1 0.2 0.0084 15.8 0.1 1.8 1 0 0 1 1 1 1 HNH endonuclease SPX PF03105.14 EXF85396.1 - 1.6e-20 74.0 8.5 3e-18 66.5 2.3 3.3 1 1 1 2 2 2 1 SPX domain Chromate_transp PF02417.10 EXF85396.1 - 0.00021 20.9 1.2 0.00031 20.3 0.8 1.2 1 0 0 1 1 1 1 Chromate transporter DUF998 PF06197.8 EXF85396.1 - 0.0026 17.1 2.5 0.0041 16.4 1.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF998) Fungal_trans PF04082.13 EXF85397.1 - 2.3e-10 39.7 1.4 2.7e-10 39.5 0.1 1.7 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF85397.1 - 1.9e-05 24.4 15.4 1.9e-05 24.4 10.7 2.4 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Acetyltransf_1 PF00583.19 EXF85399.1 - 1.3e-07 31.4 0.0 2.7e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF85399.1 - 2.6e-07 30.6 0.0 4.8e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EXF85399.1 - 0.00026 20.8 0.0 0.004 16.9 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EXF85399.1 - 0.017 15.2 0.0 0.049 13.7 0.0 1.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EXF85399.1 - 0.1 12.3 0.0 0.28 10.9 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein CcmB PF03379.8 EXF85400.1 - 0.67 9.1 0.0 0.97 8.6 0.0 1.1 1 0 0 1 1 1 0 CcmB protein Glyco_transf_28 PF03033.15 EXF85402.1 - 8.9e-13 48.1 0.0 1.8e-12 47.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.13 EXF85402.1 - 0.00041 19.0 0.0 0.001 17.6 0.0 1.6 2 0 0 2 2 2 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_trans_1_3 PF13528.1 EXF85402.1 - 0.0072 15.5 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 EXF85402.1 - 0.014 15.0 0.0 0.03 13.9 0.0 1.5 1 0 0 1 1 1 0 Glycosyltransferase family 28 C-terminal domain Formyl_trans_N PF00551.14 EXF85404.1 - 5e-26 91.3 0.0 7.1e-26 90.8 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Baculo_IE-1 PF05290.6 EXF85406.1 - 1.1 8.9 9.4 3.6 7.3 0.4 3.0 1 1 2 3 3 3 0 Baculovirus immediate-early protein (IE-0) Synaptobrevin PF00957.16 EXF85406.1 - 1.9 8.1 8.9 0.28 10.8 2.0 2.5 1 1 1 2 2 2 0 Synaptobrevin DUF1366 PF07104.6 EXF85406.1 - 2.7 7.6 16.5 0.71 9.5 4.0 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1366) FAD_binding_8 PF08022.7 EXF85407.1 - 1.8e-18 66.2 0.0 3.4e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EXF85407.1 - 2.6e-12 46.9 2.5 2.6e-12 46.9 1.7 1.8 1 1 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EXF85407.1 - 8e-09 35.5 0.0 9.6e-06 25.5 0.0 2.8 2 1 0 2 2 2 2 Ferric reductase NAD binding domain EF-hand_7 PF13499.1 EXF85407.1 - 0.0053 16.8 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 EXF85407.1 - 0.0075 15.8 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EXF85407.1 - 0.021 14.1 0.2 0.044 13.0 0.1 1.5 1 0 0 1 1 1 0 EF hand FAD_binding_6 PF00970.19 EXF85407.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain EF-hand_6 PF13405.1 EXF85407.1 - 0.063 13.1 0.3 0.18 11.8 0.2 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_5 PF13202.1 EXF85407.1 - 0.12 11.8 0.1 0.23 10.8 0.1 1.5 1 0 0 1 1 1 0 EF hand Transthyretin PF00576.16 EXF85408.1 - 2.6e-26 91.6 0.5 8.5e-17 61.0 0.4 2.6 1 1 1 2 2 2 2 HIUase/Transthyretin family DUF3507 PF12015.3 EXF85408.1 - 0.082 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) DUF566 PF04484.7 EXF85410.1 - 0.49 9.8 3.2 1.1 8.7 2.2 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF566) DUF4158 PF13700.1 EXF85411.1 - 0.097 12.1 0.2 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4158) Uds1 PF15456.1 EXF85411.1 - 0.11 12.4 1.3 1.5 8.7 0.1 2.7 2 1 1 3 3 3 0 Up-regulated During Septation DUF946 PF06101.6 EXF85412.1 - 8e-12 43.9 0.5 1.5e-11 42.9 0.3 1.4 1 0 0 1 1 1 1 Plant protein of unknown function (DUF946) TFIIIC_sub6 PF10419.4 EXF85413.1 - 1.5e-11 43.5 0.0 2.7e-11 42.7 0.0 1.5 1 0 0 1 1 1 1 TFIIIC subunit Nucleoplasmin PF03066.10 EXF85413.1 - 0.34 10.3 6.9 2.9 7.3 1.0 2.3 2 0 0 2 2 2 0 Nucleoplasmin His_biosynth PF00977.16 EXF85414.1 - 2.8e-48 164.1 0.4 1.1e-47 162.2 0.3 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.23 EXF85414.1 - 1.5e-23 83.2 0.0 2.4e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.14 EXF85414.1 - 2.3e-08 33.8 0.0 1.2e-07 31.5 0.0 2.0 1 1 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.9 EXF85414.1 - 5e-06 26.1 0.0 1.1e-05 25.0 0.0 1.6 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Dus PF01207.12 EXF85414.1 - 0.0071 15.2 0.0 0.015 14.1 0.0 1.5 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Peptidase_C26 PF07722.8 EXF85414.1 - 0.16 11.3 0.1 0.5 9.7 0.1 1.8 1 1 0 1 1 1 0 Peptidase C26 ODC_AZ PF02100.12 EXF85415.1 - 2.6e-24 84.7 0.0 4.6e-24 83.9 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme Yippee-Mis18 PF03226.9 EXF85416.1 - 7.9e-18 64.3 0.3 2.2e-17 62.8 0.2 1.8 1 1 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 EXF85416.1 - 0.2 11.5 1.0 0.99 9.2 0.1 2.1 2 0 0 2 2 2 0 C-terminal domain of RIG-I Mito_fiss_reg PF05308.6 EXF85416.1 - 3.9 6.7 14.3 7.5 5.8 9.9 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator Peptidase_M20 PF01546.23 EXF85417.1 - 9.4e-33 113.3 0.1 3.6e-32 111.3 0.1 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EXF85417.1 - 2.4e-14 53.0 0.0 3.8e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain DWNN PF08783.6 EXF85418.1 - 1.1e-29 102.1 0.0 2.2e-29 101.1 0.0 1.6 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 EXF85418.1 - 0.00043 19.7 3.6 0.0015 17.9 2.5 2.0 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EXF85418.1 - 0.0099 15.7 1.5 0.0099 15.7 1.0 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-Nse PF11789.3 EXF85418.1 - 0.028 13.9 6.4 0.073 12.6 4.4 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.10 EXF85418.1 - 0.058 13.3 0.2 0.22 11.5 0.0 2.1 2 0 0 2 2 2 0 U-box domain zf-C3HC4_2 PF13923.1 EXF85418.1 - 0.87 9.6 15.7 0.081 12.9 6.6 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EXF85418.1 - 0.98 9.1 10.7 1.9 8.1 7.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYVE_2 PF02318.11 EXF85418.1 - 1.5 8.7 4.6 0.55 10.1 1.0 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger zf-C3HC4_4 PF15227.1 EXF85418.1 - 1.6 8.6 10.9 3.9 7.4 7.6 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EXF85418.1 - 8.6 6.1 14.1 0.7 9.6 6.0 2.0 2 1 0 2 2 2 0 zinc-RING finger domain ArsA_ATPase PF02374.10 EXF85419.1 - 1.5e-114 382.1 0.2 1.8e-114 381.9 0.1 1.0 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EXF85419.1 - 8.1e-18 64.5 0.4 3.5e-17 62.4 0.3 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EXF85419.1 - 1.8e-09 37.7 0.0 1.3e-08 34.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 EXF85419.1 - 1.6e-06 27.5 0.0 2.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EXF85419.1 - 1.7e-06 27.6 0.2 0.00025 20.5 0.0 3.0 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain AAA_10 PF12846.2 EXF85419.1 - 0.0023 17.4 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain AAA_19 PF13245.1 EXF85419.1 - 0.0033 17.1 0.0 0.0087 15.7 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EXF85419.1 - 0.004 16.5 0.0 0.0073 15.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 EXF85419.1 - 0.0043 16.4 0.1 0.01 15.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain MipZ PF09140.6 EXF85419.1 - 0.0068 15.5 0.1 0.013 14.5 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ YhjQ PF06564.7 EXF85419.1 - 0.0079 15.5 0.0 0.022 14.1 0.0 1.7 2 0 0 2 2 2 1 YhjQ protein KaiC PF06745.8 EXF85419.1 - 0.018 14.1 0.5 0.097 11.7 0.0 2.0 2 1 0 2 2 2 0 KaiC AIP3 PF03915.8 EXF85419.1 - 0.032 13.1 0.1 0.046 12.6 0.1 1.2 1 0 0 1 1 1 0 Actin interacting protein 3 T2SE PF00437.15 EXF85419.1 - 0.036 12.9 0.1 0.12 11.2 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein PhoH PF02562.11 EXF85419.1 - 0.043 13.0 0.0 0.11 11.7 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein NB-ARC PF00931.17 EXF85419.1 - 0.049 12.4 0.0 0.09 11.6 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_18 PF13238.1 EXF85419.1 - 0.049 13.9 0.1 0.12 12.6 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_16 PF13191.1 EXF85419.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 EXF85419.1 - 0.15 11.1 0.0 0.29 10.1 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin SUR7 PF06687.7 EXF85421.1 - 5.5e-26 91.4 10.0 7.5e-26 91.0 6.9 1.2 1 0 0 1 1 1 1 SUR7/PalI family Claudin_2 PF13903.1 EXF85421.1 - 0.003 17.2 7.3 0.003 17.2 5.0 2.3 2 1 0 3 3 3 1 PMP-22/EMP/MP20/Claudin tight junction PAG PF15347.1 EXF85421.1 - 0.16 10.9 0.0 0.25 10.4 0.0 1.2 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched Shisa PF13908.1 EXF85421.1 - 0.66 10.1 4.5 0.54 10.4 0.1 2.4 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Herpes_gE PF02480.11 EXF85421.1 - 0.95 7.6 4.6 0.79 7.9 0.2 2.1 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E DUF1049 PF06305.6 EXF85421.1 - 0.97 8.9 0.0 0.97 8.9 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) EphA2_TM PF14575.1 EXF85421.1 - 1.7 9.0 0.0 1.7 9.0 0.0 3.2 3 1 1 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain DUF3357 PF11837.3 EXF85421.1 - 4.1 7.2 4.9 7.4 6.4 0.2 2.9 3 1 1 4 4 4 0 Domain of unknown function (DUF3357) DUF2721 PF11026.3 EXF85421.1 - 5.3 6.6 9.5 7.8 6.1 2.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) zf-DHHC PF01529.15 EXF85421.1 - 5.3 6.4 5.8 7.5 5.9 1.4 2.2 1 1 1 2 2 2 0 DHHC palmitoyltransferase MRC1 PF09444.5 EXF85423.1 - 1e-39 136.1 19.6 1e-39 136.1 13.6 7.4 6 3 2 8 8 8 1 MRC1-like domain CorA PF01544.13 EXF85424.1 - 0.035 13.1 0.0 0.065 12.2 0.0 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein CENP-K PF11802.3 EXF85424.1 - 0.17 11.0 0.1 0.27 10.4 0.0 1.2 1 0 0 1 1 1 0 Centromere-associated protein K PI-PLC-X PF00388.14 EXF85425.1 - 0.0094 15.3 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF3129 PF11327.3 EXF85426.1 - 8.9e-70 234.2 16.4 1e-68 230.7 11.4 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3129) NAD_binding_5 PF07994.7 EXF85427.1 - 4e-112 374.5 0.1 4.8e-112 374.2 0.0 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EXF85427.1 - 7.7e-46 154.5 0.5 1.7e-45 153.4 0.4 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Cytochrom_B561 PF03188.11 EXF85428.1 - 1.8e-08 34.2 10.9 4.3e-08 33.0 7.5 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 EXF85428.1 - 2.2e-05 23.9 1.1 2.2e-05 23.9 0.8 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF2427) Pox_P21 PF05313.7 EXF85428.1 - 0.034 13.3 0.2 0.23 10.6 0.0 2.0 2 0 0 2 2 2 0 Poxvirus P21 membrane protein UPF0233 PF06781.7 EXF85428.1 - 0.87 9.2 5.1 0.27 10.8 0.3 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0233) DUF2306 PF10067.4 EXF85428.1 - 1.1 9.3 10.7 0.087 12.9 2.0 2.5 1 1 1 2 2 2 0 Predicted membrane protein (DUF2306) DUF3309 PF11752.3 EXF85428.1 - 2.9 7.7 12.2 0.057 13.2 3.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3309) DUF2207 PF09972.4 EXF85428.1 - 3.5 6.1 7.4 1.6e+02 0.6 5.2 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) MFS_1 PF07690.11 EXF85429.1 - 1.4e-27 96.3 27.1 1.4e-27 96.3 18.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily VSP PF03302.8 EXF85430.1 - 0.0013 17.4 0.2 0.0018 16.9 0.2 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF3318 PF11780.3 EXF85430.1 - 0.0036 16.8 0.2 0.0051 16.3 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3318) Herpes_gE PF02480.11 EXF85430.1 - 0.039 12.2 0.0 0.067 11.4 0.0 1.3 1 1 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF1049 PF06305.6 EXF85430.1 - 0.045 13.2 0.6 0.1 12.0 0.0 1.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) Peptidase_S8 PF00082.17 EXF85432.1 - 5.6e-52 176.6 0.4 1e-51 175.7 0.3 1.5 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EXF85432.1 - 6.2e-06 26.6 0.1 1.4e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) Inhibitor_I9 PF05922.11 EXF85432.1 - 0.021 15.3 0.0 0.061 13.9 0.0 1.7 1 0 0 1 1 1 0 Peptidase inhibitor I9 tRNA-synt_2b PF00587.20 EXF85433.1 - 7.1e-36 123.3 0.0 1.2e-35 122.5 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EXF85433.1 - 5.4e-18 64.9 7.3 1.2e-17 63.8 5.1 1.6 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Cytochrom_C552 PF02335.10 EXF85433.1 - 0.33 9.5 5.3 0.47 9.0 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c552 SHNi-TPR PF10516.4 EXF85434.1 - 3.3e-15 55.0 0.4 3.3e-15 55.0 0.3 2.4 3 0 0 3 3 3 1 SHNi-TPR TPR_11 PF13414.1 EXF85434.1 - 1.4e-09 37.4 2.5 7.6e-06 25.4 0.0 2.8 2 1 0 2 2 2 2 TPR repeat TPR_12 PF13424.1 EXF85434.1 - 6.3e-09 35.6 0.7 0.0017 18.2 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EXF85434.1 - 7.5e-05 22.1 2.3 0.00058 19.3 0.3 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EXF85434.1 - 0.00011 22.7 0.0 0.0056 17.3 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EXF85434.1 - 0.00017 21.6 0.2 0.25 11.4 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EXF85434.1 - 0.00025 20.6 9.7 0.00064 19.4 0.2 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat UPF0227 PF05728.7 EXF85434.1 - 0.051 13.3 0.2 0.66 9.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) TPR_8 PF13181.1 EXF85434.1 - 0.14 11.9 0.2 0.14 11.9 0.2 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF2508 PF10704.4 EXF85434.1 - 3.1 8.0 10.3 7.4 6.8 0.1 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF2508) RabGAP-TBC PF00566.13 EXF85435.1 - 5.4e-47 160.0 0.0 1.3e-46 158.7 0.0 1.6 1 1 0 1 1 1 1 Rab-GTPase-TBC domain RRM_1 PF00076.17 EXF85436.1 - 6.4e-38 128.2 0.3 5e-18 64.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF85436.1 - 1.4e-27 95.4 3.6 4.3e-14 52.2 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF85436.1 - 1.1e-12 47.5 0.0 4.4e-05 23.2 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EXF85436.1 - 0.015 15.0 0.1 4.9 7.0 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EXF85436.1 - 0.11 12.3 0.1 21 4.9 0.0 2.6 2 0 0 2 2 2 0 RNA binding motif DUF1631 PF07793.6 EXF85436.1 - 4.3 5.3 9.7 6.9 4.6 6.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) GCS PF03074.11 EXF85437.1 - 2.1e-151 504.1 0.0 1.2e-119 399.6 0.1 2.1 2 0 0 2 2 2 2 Glutamate-cysteine ligase MFS_1 PF07690.11 EXF85439.1 - 4.6e-11 42.0 42.2 4.6e-11 42.0 29.2 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.11 EXF85439.1 - 2.6e-05 23.7 5.4 2.6e-05 23.7 3.7 2.6 2 1 0 2 2 2 1 Ion channel regulatory protein UNC-93 GARS_A PF01071.14 EXF85440.1 - 1.6e-82 275.8 0.0 2.7e-82 275.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EXF85440.1 - 5.8e-35 119.7 0.0 1.9e-34 118.1 0.0 2.0 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EXF85440.1 - 4.7e-29 101.3 0.1 1.9e-27 96.1 0.0 2.6 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EXF85440.1 - 3.9e-26 91.0 0.2 1.6e-25 89.1 0.1 2.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EXF85440.1 - 9.7e-16 57.7 1.2 4e-15 55.8 0.4 2.4 2 0 0 2 2 1 1 AIR synthase related protein, N-terminal domain TPR_11 PF13414.1 EXF85440.1 - 3.4e-13 49.0 16.7 7.5e-06 25.5 0.8 6.6 6 1 0 7 7 6 2 TPR repeat ATP-grasp_4 PF13535.1 EXF85440.1 - 1.8e-09 37.5 0.0 4.6e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EXF85440.1 - 2.8e-07 29.5 0.0 5.4e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon TPR_17 PF13431.1 EXF85440.1 - 9.5e-07 28.5 0.3 0.065 13.4 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EXF85440.1 - 2.4e-06 28.0 16.3 0.043 14.4 0.8 7.0 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_20 PF14561.1 EXF85440.1 - 3.2e-06 27.1 1.4 2.6 8.2 0.1 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EXF85440.1 - 3.9e-06 27.1 15.7 0.2 12.0 0.4 6.3 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.1 EXF85440.1 - 6.9e-06 26.2 9.6 0.51 11.1 0.0 7.4 5 2 2 7 7 6 2 Tetratricopeptide repeat CPSase_L_D2 PF02786.12 EXF85440.1 - 0.0001 21.6 0.2 0.00021 20.6 0.1 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp PF02222.17 EXF85440.1 - 0.00018 20.8 0.0 0.00046 19.5 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain TPR_2 PF07719.12 EXF85440.1 - 0.00025 20.7 14.6 2.7 8.1 0.0 7.1 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_12 PF13424.1 EXF85440.1 - 0.0032 17.3 1.4 0.0032 17.3 0.9 4.9 3 1 1 4 4 4 1 Tetratricopeptide repeat ATP-grasp_3 PF02655.9 EXF85440.1 - 0.0034 17.2 0.0 0.0078 16.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain TPR_1 PF00515.23 EXF85440.1 - 0.012 15.2 13.0 3.8 7.2 0.0 6.8 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 EXF85440.1 - 0.014 15.1 7.9 21 5.2 0.2 6.3 7 0 0 7 7 5 0 Tetratricopeptide repeat Glyoxalase_2 PF12681.2 EXF85440.1 - 0.039 14.5 0.0 22 5.6 0.0 3.3 2 0 0 2 2 2 0 Glyoxalase-like domain TPR_9 PF13371.1 EXF85440.1 - 0.04 13.7 9.9 0.091 12.6 0.1 4.6 4 1 1 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.1 EXF85440.1 - 0.062 13.7 3.5 80 4.0 0.0 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat RimK PF08443.6 EXF85440.1 - 0.12 11.8 0.0 0.27 10.6 0.0 1.6 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Mg296 PF09644.5 EXF85440.1 - 0.13 12.1 0.0 0.49 10.2 0.0 2.0 1 0 0 1 1 1 0 Mg296 protein DUF2989 PF11207.3 EXF85440.1 - 0.17 11.3 0.6 0.41 10.0 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) Apc3 PF12895.2 EXF85440.1 - 0.37 10.9 11.1 0.44 10.7 2.8 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 SAM_2 PF07647.12 EXF85441.1 - 1.3e-10 40.9 0.1 2.4e-10 40.1 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EXF85441.1 - 4.4e-06 26.7 0.3 9e-06 25.7 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) IGR PF09597.5 EXF85441.1 - 0.05 13.4 0.2 0.14 12.0 0.1 1.7 1 0 0 1 1 1 0 IGR protein motif Ribosomal_L29e PF01779.12 EXF85442.1 - 4e-23 80.9 9.2 6.1e-23 80.3 6.4 1.3 1 0 0 1 1 1 1 Ribosomal L29e protein family Mito_carr PF00153.22 EXF85443.1 - 9.8e-55 182.2 0.5 1.3e-18 66.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_C2 PF00648.16 EXF85444.1 - 2.9e-21 75.7 0.0 4.7e-21 75.0 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.17 EXF85444.1 - 1.3e-14 54.0 0.0 7.3e-12 45.1 0.0 3.2 2 1 0 2 2 2 2 Calpain large subunit, domain III MIT PF04212.13 EXF85444.1 - 0.00083 19.1 0.4 0.0018 18.1 0.3 1.5 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain zf-C2H2_4 PF13894.1 EXF85445.1 - 0.0019 18.3 8.1 2.3 8.7 0.1 3.8 3 0 0 3 3 3 3 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF85445.1 - 0.0022 18.2 7.9 1.2 9.6 0.1 3.8 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EXF85445.1 - 0.044 14.0 3.5 4.2 7.8 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger double domain DUF4201 PF13870.1 EXF85447.1 - 0.0026 17.2 3.3 0.0026 17.2 2.3 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4201) DUF2205 PF10224.4 EXF85447.1 - 0.062 12.8 2.3 0.19 11.3 1.6 1.9 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) TPR_MLP1_2 PF07926.7 EXF85447.1 - 1.9 8.2 12.9 0.069 12.8 4.0 2.3 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein BTB PF00651.26 EXF85448.1 - 0.00019 21.3 0.1 0.00035 20.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain zf-C3HC4_2 PF13923.1 EXF85448.1 - 9.6 6.3 7.5 1.9 8.5 2.6 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.1 EXF85449.1 - 0.09 12.0 0.8 0.23 10.6 0.5 1.7 1 0 0 1 1 1 0 zinc-ribbon domain DZR PF12773.2 EXF85449.1 - 0.21 11.4 2.1 0.57 10.0 1.5 1.7 1 0 0 1 1 1 0 Double zinc ribbon LicD PF04991.8 EXF85450.1 - 2.4e-30 106.2 7.5 6.9e-29 101.4 5.2 2.2 1 1 0 1 1 1 1 LicD family NUDIX PF00293.23 EXF85451.1 - 2.6e-10 40.0 0.0 4.2e-10 39.4 0.0 1.3 1 1 0 1 1 1 1 NUDIX domain ER_lumen_recept PF00810.13 EXF85452.1 - 1.7e-33 116.1 6.0 2.7e-33 115.5 4.1 1.3 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EXF85452.1 - 0.08 12.4 0.1 0.08 12.4 0.0 3.1 3 0 0 3 3 3 0 PQ loop repeat DUF4234 PF14018.1 EXF85452.1 - 7.3 6.4 14.1 1.2 8.9 3.5 3.2 2 2 0 2 2 2 0 Domain of unknown function (DUF4234) Arabinose_trans PF04602.7 EXF85454.1 - 0.011 13.9 0.9 0.013 13.7 0.6 1.0 1 0 0 1 1 1 0 Mycobacterial cell wall arabinan synthesis protein DUF1049 PF06305.6 EXF85454.1 - 0.33 10.4 2.1 0.57 9.7 0.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) adh_short PF00106.20 EXF85455.1 - 1.7e-14 54.0 0.9 3e-14 53.3 0.6 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF85455.1 - 0.00031 20.4 0.4 0.0006 19.5 0.2 1.4 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF85455.1 - 0.013 15.3 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase ADK PF00406.17 EXF85456.1 - 2.8e-37 127.9 0.0 8.6e-21 74.3 0.0 2.1 2 0 0 2 2 2 2 Adenylate kinase ADK_lid PF05191.9 EXF85456.1 - 1.4e-12 47.0 0.0 5.2e-12 45.2 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase, active site lid AAA_18 PF13238.1 EXF85456.1 - 9.6e-05 22.6 0.0 0.00051 20.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EXF85456.1 - 0.00037 21.2 0.0 0.0011 19.8 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EXF85456.1 - 0.0079 16.0 0.0 0.054 13.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EXF85456.1 - 0.055 13.1 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Guanylate_kin PF00625.16 EXF85456.1 - 0.092 12.1 0.0 0.24 10.7 0.0 1.6 2 0 0 2 2 2 0 Guanylate kinase Zeta_toxin PF06414.7 EXF85456.1 - 0.15 11.1 0.0 0.24 10.4 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin LETM1 PF07766.8 EXF85457.1 - 3.8e-107 357.3 0.6 6.8e-107 356.4 0.4 1.4 1 0 0 1 1 1 1 LETM1-like protein SAP PF02037.22 EXF85457.1 - 0.00049 19.5 0.1 0.36 10.4 0.0 3.1 3 0 0 3 3 3 2 SAP domain PX PF00787.19 EXF85458.1 - 8.7e-21 73.8 0.3 2.8e-20 72.2 0.2 1.9 1 0 0 1 1 1 1 PX domain Vps5 PF09325.5 EXF85458.1 - 3.4e-11 42.8 12.0 8.1e-07 28.5 1.6 2.2 2 0 0 2 2 2 2 Vps5 C terminal like Sigma70_r1_1 PF03979.9 EXF85458.1 - 0.0048 16.7 0.3 0.023 14.6 0.2 2.2 1 0 0 1 1 1 1 Sigma-70 factor, region 1.1 IncA PF04156.9 EXF85458.1 - 0.0058 16.2 3.3 0.0058 16.2 2.3 2.0 2 0 0 2 2 2 1 IncA protein Reo_sigmaC PF04582.7 EXF85458.1 - 0.031 13.4 0.0 0.05 12.7 0.0 1.4 1 0 0 1 1 1 0 Reovirus sigma C capsid protein BAR PF03114.13 EXF85458.1 - 0.054 13.0 12.2 0.18 11.2 8.5 1.8 1 1 0 1 1 1 0 BAR domain FtsH_ext PF06480.10 EXF85458.1 - 0.085 13.0 0.3 0.26 11.4 0.0 2.0 2 0 0 2 2 2 0 FtsH Extracellular DUF1664 PF07889.7 EXF85458.1 - 0.15 11.8 2.4 3.8 7.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ADIP PF11559.3 EXF85458.1 - 0.19 11.6 10.4 12 5.8 0.2 3.2 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding Occludin_ELL PF07303.8 EXF85458.1 - 0.32 11.7 0.0 0.32 11.7 0.0 3.7 3 2 1 4 4 4 0 Occludin homology domain Peptidase_S8 PF00082.17 EXF85459.1 - 2.6e-54 184.2 2.9 4e-54 183.6 2.0 1.3 1 0 0 1 1 1 1 Subtilase family P_proprotein PF01483.15 EXF85459.1 - 7.7e-29 99.3 1.2 2e-28 97.9 0.9 1.8 1 0 0 1 1 1 1 Proprotein convertase P-domain Herpes_gE PF02480.11 EXF85459.1 - 0.082 11.1 0.0 0.13 10.4 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E PepSY_TM_2 PF13703.1 EXF85459.1 - 0.13 12.4 0.3 0.39 10.9 0.2 1.7 1 0 0 1 1 1 0 PepSY-associated TM helix PhoD PF09423.5 EXF85460.1 - 6.7e-08 31.5 0.0 1.2e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase RRM_1 PF00076.17 EXF85461.1 - 2.4e-13 49.5 0.0 3.7e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF85461.1 - 2.8e-11 43.2 0.0 4.3e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF85461.1 - 4.2e-08 32.9 0.0 6.6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EXF85461.1 - 0.048 13.5 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 RNA binding motif HpcH_HpaI PF03328.9 EXF85463.1 - 1.5e-41 141.6 0.0 3.2e-41 140.6 0.0 1.5 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EXF85463.1 - 9.9e-11 41.0 0.0 2e-06 26.8 0.0 2.1 2 0 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold PK PF00224.16 EXF85463.1 - 0.0012 17.5 0.0 0.0016 17.1 0.0 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PEPcase_2 PF14010.1 EXF85463.1 - 0.01 14.1 0.1 0.016 13.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase DUF846 PF05832.7 EXF85464.1 - 3.4e-42 143.5 6.1 3.9e-42 143.3 4.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Tic20 PF09685.5 EXF85464.1 - 0.024 14.5 1.1 0.024 14.5 0.8 1.6 2 0 0 2 2 2 0 Tic20-like protein Wzy_C PF04932.10 EXF85464.1 - 0.13 12.0 2.1 0.21 11.3 1.5 1.4 1 0 0 1 1 1 0 O-Antigen ligase DUF4191 PF13829.1 EXF85464.1 - 0.26 10.3 1.2 0.39 9.7 0.6 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) Cyclin PF08613.6 EXF85465.1 - 5.3e-15 56.1 0.0 9.9e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EXF85465.1 - 0.00081 18.9 0.0 0.0014 18.2 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Iron_permease PF04120.7 EXF85466.1 - 0.13 11.8 0.0 0.24 10.9 0.0 1.4 1 0 0 1 1 1 0 Low affinity iron permease Chs3p PF12271.3 EXF85467.1 - 2.2e-137 456.9 16.4 2.5e-137 456.6 11.3 1.0 1 0 0 1 1 1 1 Chitin synthase III catalytic subunit DUF3716 PF12511.3 EXF85468.1 - 2.1e-09 36.8 7.2 3.7e-09 36.0 5.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3716) RE_HindIII PF09518.5 EXF85468.1 - 0.32 9.8 5.1 0.91 8.3 3.5 1.7 1 0 0 1 1 1 0 HindIII restriction endonuclease Acyl_transf_3 PF01757.17 EXF85469.1 - 3.6e-24 85.2 35.9 3.6e-24 85.2 24.9 1.7 2 0 0 2 2 2 1 Acyltransferase family Cu_amine_oxid PF01179.15 EXF85470.1 - 5.2e-160 532.6 0.0 8.2e-160 532.0 0.0 1.3 2 0 0 2 2 2 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.11 EXF85470.1 - 8.8e-10 38.5 0.0 1.9e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain Cu_amine_oxidN3 PF02728.11 EXF85470.1 - 5.7e-07 29.5 0.0 1.1e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Fungal_trans_2 PF11951.3 EXF85471.1 - 3.1e-33 114.9 6.8 4.5e-33 114.3 4.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF85471.1 - 2.9e-08 33.4 9.4 2.9e-08 33.4 6.5 1.8 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Pro_racemase PF05544.6 EXF85472.1 - 2.5e-64 217.1 0.0 2.9e-64 216.9 0.0 1.0 1 0 0 1 1 1 1 Proline racemase PhzC-PhzF PF02567.11 EXF85472.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Phenazine biosynthesis-like protein MFS_1 PF07690.11 EXF85473.1 - 9.7e-21 73.8 55.2 4.4e-19 68.4 21.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF85473.1 - 0.00017 20.3 1.0 0.00017 20.3 0.7 3.1 3 0 0 3 3 3 2 Sugar (and other) transporter Peptidase_M56 PF05569.6 EXF85473.1 - 0.044 12.7 0.5 0.59 9.0 0.0 2.4 2 0 0 2 2 2 0 BlaR1 peptidase M56 MFS_1 PF07690.11 EXF85474.1 - 4.1e-33 114.5 14.1 4.1e-33 114.5 9.8 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF85474.1 - 5.3e-06 25.2 5.1 5.3e-06 25.2 3.6 1.7 2 0 0 2 2 2 1 Sugar (and other) transporter ADH_N PF08240.7 EXF85475.1 - 6.2e-09 35.6 0.2 1.9e-08 34.0 0.2 1.8 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EXF85475.1 - 8.9e-09 36.3 0.0 2.2e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EXF85475.1 - 1.1e-05 24.9 0.0 1.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Aa_trans PF01490.13 EXF85476.1 - 4.8e-49 166.9 38.5 5.5e-49 166.7 26.7 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein 4HBT_3 PF13622.1 EXF85477.1 - 7.1e-48 163.5 0.0 8.3e-48 163.3 0.0 1.0 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EXF85477.1 - 0.0025 17.4 0.0 0.0041 16.7 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA thioesterase Tyrosinase PF00264.15 EXF85478.1 - 6.4e-48 163.8 1.1 9.5e-48 163.2 0.8 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase Polysacc_deac_1 PF01522.16 EXF85480.1 - 5.3e-29 100.3 0.0 8.9e-29 99.6 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EXF85480.1 - 5.4e-19 67.8 73.0 2.3e-07 30.6 16.6 3.8 3 1 1 4 4 4 3 Chitin recognition protein Glyco_hydro_57 PF03065.10 EXF85480.1 - 0.14 11.0 0.0 0.23 10.3 0.0 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 57 Chitin_synth_2 PF03142.10 EXF85481.1 - 7.8e-41 140.0 3.2 1.2e-30 106.4 0.2 2.4 2 1 0 2 2 2 2 Chitin synthase Glycos_transf_2 PF00535.21 EXF85481.1 - 3.5e-08 33.3 0.0 0.0051 16.5 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EXF85481.1 - 6.6e-07 29.3 0.2 0.021 14.6 0.0 3.1 3 0 0 3 3 3 3 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EXF85481.1 - 7.9e-07 28.9 3.6 7.9e-07 28.9 2.5 2.8 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Polysacc_deac_1 PF01522.16 EXF85482.1 - 5.5e-26 90.6 0.0 9.3e-26 89.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Chitin_bind_1 PF00187.14 EXF85482.1 - 4.8e-16 58.4 78.9 5.1e-06 26.3 11.8 3.7 3 0 0 3 3 3 3 Chitin recognition protein UDPG_MGDP_dh_N PF03721.9 EXF85484.1 - 1.5e-21 76.6 0.1 6.1e-19 68.1 0.0 2.2 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh PF00984.14 EXF85484.1 - 1.2e-17 63.8 0.0 3.1e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.10 EXF85484.1 - 3.5e-07 30.1 0.0 6.7e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_C PF03720.10 EXF85484.1 - 0.0034 17.4 0.0 0.0068 16.5 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Nucleo_P87 PF07267.6 EXF85485.1 - 2.3 6.8 7.1 2.9 6.4 4.9 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 PX PF00787.19 EXF85486.1 - 3.6e-18 65.4 0.1 7.1e-18 64.4 0.0 1.5 1 0 0 1 1 1 1 PX domain Ribosomal_L18e PF00828.14 EXF85487.1 - 4.8e-15 56.0 0.3 9e-15 55.1 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 adh_short PF00106.20 EXF85488.1 - 5.2e-13 49.2 0.0 7.6e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EXF85488.1 - 0.0032 17.5 0.1 0.0075 16.2 0.0 1.6 2 0 0 2 2 2 1 NADH(P)-binding KR PF08659.5 EXF85488.1 - 0.0048 16.5 0.0 0.0088 15.7 0.0 1.5 1 0 0 1 1 1 1 KR domain Glyco_transf_15 PF01793.11 EXF85489.1 - 2.2e-129 431.1 0.6 2.9e-129 430.7 0.4 1.1 1 0 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase ILVD_EDD PF00920.16 EXF85490.1 - 5.7e-198 658.5 1.1 6.6e-198 658.3 0.7 1.0 1 0 0 1 1 1 1 Dehydratase family GFA PF04828.9 EXF85491.1 - 1.6e-13 50.3 0.2 1.6e-13 50.3 0.1 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme PTR2 PF00854.16 EXF85493.1 - 6.9e-40 136.9 12.7 1.6e-22 79.7 2.4 2.2 2 0 0 2 2 2 2 POT family DAP_epimerase PF01678.14 EXF85493.1 - 0.091 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Diaminopimelate epimerase RBM1CTR PF08081.6 EXF85494.1 - 0.46 10.2 5.4 0.26 11.0 0.7 2.6 2 1 0 3 3 3 0 RBM1CTR (NUC064) family 2-Hacid_dh_C PF02826.14 EXF85495.1 - 2.5e-46 157.0 0.0 3.5e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EXF85495.1 - 4.3e-07 29.4 0.0 8.3e-07 28.5 0.0 1.5 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EXF85495.1 - 0.0046 16.8 0.1 0.0099 15.7 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EXF85495.1 - 0.035 13.4 0.0 0.055 12.8 0.0 1.3 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain Fungal_trans_2 PF11951.3 EXF85496.1 - 2.8e-05 22.8 0.3 5.9e-05 21.8 0.0 1.6 2 0 0 2 2 2 1 Fungal specific transcription factor domain F-box-like PF12937.2 EXF85497.1 - 0.0044 16.7 0.2 0.012 15.2 0.1 1.9 1 0 0 1 1 1 1 F-box-like adh_short PF00106.20 EXF85500.1 - 4.8e-22 78.6 0.1 6.5e-22 78.2 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF85500.1 - 2.8e-10 40.1 0.1 5.4e-10 39.2 0.1 1.6 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EXF85500.1 - 0.0013 17.5 0.1 0.0023 16.7 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Ras PF00071.17 EXF85501.1 - 6.5e-43 145.9 0.0 1.2e-42 145.0 0.0 1.4 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EXF85501.1 - 7.6e-15 55.4 0.0 1.2e-14 54.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EXF85501.1 - 6.2e-11 41.8 0.0 2.2e-10 40.0 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family AAA_33 PF13671.1 EXF85501.1 - 0.0013 18.6 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Gtr1_RagA PF04670.7 EXF85501.1 - 0.0015 17.7 0.0 0.0019 17.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EXF85501.1 - 0.0019 18.1 0.0 0.0031 17.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EXF85501.1 - 0.0054 16.2 0.0 0.2 11.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EXF85501.1 - 0.011 15.8 0.0 0.019 15.0 0.0 1.4 1 1 0 1 1 1 0 AAA domain SRPRB PF09439.5 EXF85501.1 - 0.014 14.5 0.0 0.021 14.0 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 EXF85501.1 - 0.024 14.5 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF258 PF03193.11 EXF85501.1 - 0.029 13.5 0.0 0.048 12.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EXF85501.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EXF85501.1 - 0.11 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 ABC transporter NACHT PF05729.7 EXF85501.1 - 0.13 11.9 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain Arch_ATPase PF01637.13 EXF85501.1 - 0.19 11.3 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Archaeal ATPase Glyco_hydro_2_N PF02837.13 EXF85502.1 - 4.9e-11 42.4 0.1 1.5e-10 40.8 0.1 1.8 1 1 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.16 EXF85502.1 - 1.1e-10 41.9 0.0 3.5e-10 40.3 0.0 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 EXF85502.1 - 2.2e-06 26.8 0.0 3.6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain IMS PF00817.15 EXF85504.1 - 3.1e-40 137.3 0.0 4.9e-40 136.7 0.0 1.3 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.3 EXF85504.1 - 4.6e-12 45.9 0.0 1e-10 41.6 0.0 2.6 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain NmrA PF05368.8 EXF85505.1 - 0.00059 19.1 0.0 0.00074 18.8 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EXF85505.1 - 0.0012 18.8 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF85505.1 - 0.0013 18.3 0.0 0.0019 17.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF85505.1 - 0.018 14.4 0.0 0.025 14.0 0.0 1.1 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EXF85505.1 - 0.021 13.7 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Male sterility protein DapB_N PF01113.15 EXF85505.1 - 0.024 14.5 0.0 0.034 14.0 0.0 1.1 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.1 EXF85505.1 - 0.047 13.6 0.1 0.054 13.5 0.0 1.1 1 0 0 1 1 1 0 NADH(P)-binding Shikimate_DH PF01488.15 EXF85505.1 - 0.1 12.6 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ADH_N PF08240.7 EXF85506.1 - 4.9e-30 103.4 0.4 1.2e-29 102.2 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF85506.1 - 3.3e-22 78.4 0.1 5.3e-22 77.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF85506.1 - 0.00047 21.0 0.0 0.0014 19.5 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EXF85506.1 - 0.0039 17.7 0.0 0.011 16.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain UDPG_MGDP_dh_N PF03721.9 EXF85506.1 - 0.005 16.2 0.1 0.0099 15.2 0.0 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AlaDh_PNT_C PF01262.16 EXF85506.1 - 0.0088 15.6 0.2 0.015 14.8 0.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 EXF85506.1 - 0.037 12.4 0.3 0.055 11.9 0.2 1.2 1 0 0 1 1 1 0 HI0933-like protein AdoHcyase_NAD PF00670.16 EXF85506.1 - 0.037 13.8 0.3 0.43 10.3 0.2 2.2 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Pyr_redox PF00070.22 EXF85506.1 - 0.08 13.3 0.3 0.19 12.1 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EXF85506.1 - 0.11 11.6 0.1 0.23 10.5 0.0 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain MARVEL PF01284.18 EXF85507.1 - 5.8e-09 35.9 14.1 5.8e-09 35.9 9.8 2.2 1 1 1 2 2 2 1 Membrane-associating domain PA14_2 PF10528.4 EXF85509.1 - 6.7e-21 74.3 6.0 1.8e-20 73.0 4.2 1.7 1 0 0 1 1 1 1 GLEYA domain PA14 PF07691.7 EXF85509.1 - 3.9e-09 36.3 0.4 1e-08 34.9 0.3 1.7 1 0 0 1 1 1 1 PA14 domain zf-RING_2 PF13639.1 EXF85513.1 - 6.6e-13 48.2 3.5 6.6e-13 48.2 2.4 1.6 2 0 0 2 2 1 1 Ring finger domain zf-rbx1 PF12678.2 EXF85513.1 - 1.5e-12 47.4 0.7 2.7e-12 46.6 0.5 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EXF85513.1 - 3.6e-07 29.9 0.4 7.1e-07 28.9 0.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.1 EXF85513.1 - 3.2e-06 26.7 2.9 5.2e-06 26.0 2.0 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EXF85513.1 - 4e-06 26.7 4.0 4e-06 26.7 2.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EXF85513.1 - 5.3e-05 22.7 3.2 8.8e-05 22.0 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EXF85513.1 - 6e-05 22.6 2.3 0.00011 21.7 1.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EXF85513.1 - 0.0012 18.4 1.4 0.0028 17.3 1.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger FANCL_C PF11793.3 EXF85513.1 - 0.012 15.5 4.6 0.21 11.5 3.2 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Baculo_RING PF05883.6 EXF85513.1 - 0.14 11.9 0.2 0.24 11.2 0.1 1.3 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-Nse PF11789.3 EXF85513.1 - 0.28 10.7 1.9 0.65 9.5 1.3 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EXF85513.1 - 2 8.3 4.2 0.57 10.0 0.8 1.7 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Cullin PF00888.17 EXF85514.1 - 2.6e-50 171.5 0.0 1e-49 169.6 0.0 2.0 2 1 0 2 2 2 1 Cullin family APC2 PF08672.6 EXF85514.1 - 8.7e-19 67.5 0.4 2.4e-18 66.1 0.1 1.9 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 PEP-utilisers_N PF05524.8 EXF85514.1 - 0.6 9.9 4.6 0.69 9.7 1.3 2.5 2 1 1 3 3 3 0 PEP-utilising enzyme, N-terminal zf-C2H2 PF00096.21 EXF85515.1 - 0.0026 18.0 3.7 0.31 11.4 0.4 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF85515.1 - 0.0029 17.8 4.6 0.37 11.2 0.1 2.6 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EXF85515.1 - 0.005 17.0 1.0 0.012 15.8 0.0 2.2 2 0 0 2 2 2 1 Zinc-finger double domain zf-ribbon_3 PF13248.1 EXF85515.1 - 0.043 13.0 0.3 0.074 12.2 0.2 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-C2H2_6 PF13912.1 EXF85515.1 - 0.081 12.8 2.5 7 6.7 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger MCM PF00493.18 EXF85518.1 - 8.8e-140 465.1 0.0 1.4e-139 464.5 0.0 1.3 1 0 0 1 1 1 1 MCM2/3/5 family MCM2_N PF12619.3 EXF85518.1 - 7.5e-31 107.2 34.6 7.5e-31 107.2 24.0 2.9 3 0 0 3 3 3 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.1 EXF85518.1 - 4.1e-20 72.4 0.1 9.1e-20 71.3 0.1 1.6 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EXF85518.1 - 1.5e-07 30.7 1.0 5.9e-06 25.5 0.0 2.7 2 1 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EXF85518.1 - 1.9e-06 27.6 0.0 4.8e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EXF85518.1 - 0.0022 17.5 0.2 0.015 14.7 0.1 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.6 EXF85518.1 - 0.0037 16.8 0.1 0.019 14.5 0.0 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) zf-TFIIB PF13453.1 EXF85518.1 - 0.12 11.6 1.2 0.27 10.4 0.8 1.7 1 0 0 1 1 1 0 Transcription factor zinc-finger Zn_ribbon_2 PF12674.2 EXF85518.1 - 0.12 12.7 0.6 0.38 11.1 0.4 1.8 1 0 0 1 1 1 0 Putative zinc ribbon domain zf-UBR PF02207.15 EXF85519.1 - 4e-16 58.4 5.3 4e-16 58.4 3.7 3.4 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) AA_permease PF00324.16 EXF85520.1 - 1.1e-101 340.5 37.7 1.3e-101 340.3 26.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF85520.1 - 1.9e-34 118.9 42.6 2.3e-34 118.7 29.5 1.0 1 0 0 1 1 1 1 Amino acid permease SPATA24 PF15175.1 EXF85521.1 - 0.043 13.5 0.1 0.24 11.0 0.0 2.2 2 1 0 2 2 2 0 Spermatogenesis-associated protein 24 FlgN PF05130.7 EXF85521.1 - 0.058 13.6 0.6 0.058 13.6 0.4 2.5 2 1 1 3 3 3 0 FlgN protein Kinetocho_Slk19 PF12709.2 EXF85521.1 - 0.11 12.5 3.7 0.25 11.4 0.4 2.8 2 1 1 3 3 3 0 Central kinetochore-associated DUF2353 PF09789.4 EXF85521.1 - 0.27 10.4 4.8 0.42 9.8 3.3 1.3 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) CENP-Q PF13094.1 EXF85521.1 - 0.49 10.3 9.1 0.063 13.3 2.3 2.4 3 1 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Phage_lysis PF03245.8 EXF85521.1 - 0.97 9.4 8.8 0.3 11.0 1.0 3.0 4 1 0 4 4 4 0 Bacteriophage Rz lysis protein Glyco_hydro_31 PF01055.21 EXF85523.1 - 8.1e-173 575.2 1.4 1e-172 574.9 1.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EXF85523.1 - 1.7e-12 47.0 1.9 2.2e-11 43.4 1.1 2.9 2 0 0 2 2 2 1 Galactose mutarotase-like Glyco_hydro_43 PF04616.9 EXF85524.1 - 2e-17 63.2 4.7 3.5e-17 62.4 3.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Fungal_trans PF04082.13 EXF85526.1 - 3.7e-14 52.2 2.9 5.9e-14 51.5 2.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF3415 PF11895.3 EXF85526.1 - 0.094 12.5 0.4 0.91 9.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3415) CAP_N PF01213.14 EXF85526.1 - 7.8 5.6 5.4 11 5.1 1.5 2.3 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal NAD_binding_10 PF13460.1 EXF85527.1 - 3.9e-18 66.0 0.1 5.5e-18 65.6 0.1 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF85527.1 - 8.4e-09 35.1 0.0 1.3e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EXF85527.1 - 0.016 15.1 0.2 0.039 13.8 0.0 1.8 2 0 0 2 2 2 0 short chain dehydrogenase DHHA1 PF02272.14 EXF85527.1 - 0.04 13.6 0.2 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 DHHA1 domain RmlD_sub_bind PF04321.12 EXF85527.1 - 0.079 11.8 0.1 0.21 10.4 0.0 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain 2OG-FeII_Oxy PF03171.15 EXF85528.1 - 0.00036 20.7 0.0 0.00064 19.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EXF85528.1 - 0.001 19.5 0.0 0.0031 18.0 0.0 2.0 2 1 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal PIGA PF08288.7 EXF85529.1 - 1.4e-44 150.3 3.2 3e-44 149.3 0.7 2.3 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EXF85529.1 - 8.9e-30 103.3 0.0 1.3e-29 102.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EXF85529.1 - 1.8e-16 60.3 0.7 3.1e-16 59.5 0.5 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EXF85529.1 - 2.2e-16 60.2 0.0 4e-16 59.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EXF85529.1 - 6e-13 49.2 0.0 1.1e-12 48.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 EXF85529.1 - 8e-07 28.9 0.4 1.3e-06 28.3 0.3 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 EXF85529.1 - 8.5e-06 25.9 0.1 2.4e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferases group 1 DEAD PF00270.24 EXF85530.1 - 3.7e-32 111.1 0.1 2.2e-16 59.7 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF85530.1 - 6.9e-19 67.4 0.0 1.4e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EXF85530.1 - 2.5e-08 33.9 6.2 3.6e-08 33.4 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EXF85530.1 - 0.019 14.2 0.0 0.019 14.2 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain Colipase-like PF15083.1 EXF85531.1 - 0.07 13.0 0.7 0.11 12.4 0.5 1.2 1 0 0 1 1 1 0 Colipase-like MDH PF02315.11 EXF85531.1 - 0.32 10.9 0.1 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 Methanol dehydrogenase beta subunit Draxin PF15550.1 EXF85531.1 - 0.38 10.3 2.9 0.44 10.1 2.0 1.0 1 0 0 1 1 1 0 Draxin Toxin_18 PF08087.6 EXF85531.1 - 1.1 9.1 6.9 0.56 10.0 0.3 2.4 2 0 0 2 2 2 0 Conotoxin O-superfamily Metallothio_6 PF05522.6 EXF85531.1 - 3.9 7.8 6.7 7 7.0 4.7 1.5 1 1 0 1 1 1 0 Metallothionein Acetyltransf_1 PF00583.19 EXF85532.1 - 4.5e-09 36.2 0.1 1.2e-08 34.8 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF85532.1 - 3.3e-08 33.5 0.0 1.6e-07 31.3 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EXF85532.1 - 2e-06 27.4 0.0 3.7e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EXF85532.1 - 7.3e-06 25.8 0.0 1.5e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EXF85532.1 - 0.00016 21.8 0.0 0.0013 18.8 0.0 2.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EXF85532.1 - 0.0039 17.0 0.0 0.0077 16.0 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Thiolase_C PF02803.13 EXF85533.1 - 2.2e-13 49.7 3.3 3.6e-13 49.0 0.5 2.7 2 1 1 3 3 3 1 Thiolase, C-terminal domain ACP_syn_III PF08545.5 EXF85533.1 - 9.3e-08 31.6 0.3 5.4e-06 25.9 0.1 2.5 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ketoacyl-synt PF00109.21 EXF85533.1 - 9.4e-05 22.0 0.0 0.0002 20.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 EXF85533.1 - 0.00033 19.7 0.1 0.0018 17.2 0.1 2.3 3 0 0 3 3 3 1 Thiolase, N-terminal domain Ketoacyl-synt_C PF02801.17 EXF85533.1 - 0.0025 17.6 0.2 0.13 12.1 0.0 2.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.6 EXF85533.1 - 0.03 12.7 1.7 0.11 10.8 0.1 2.4 3 0 0 3 3 3 0 Stage V sporulation protein AD (SpoVAD) FAD_binding_3 PF01494.14 EXF85534.1 - 1.3e-23 83.6 0.0 5.4e-23 81.6 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF85534.1 - 3.4e-09 36.0 0.6 0.00028 19.9 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.22 EXF85534.1 - 1.2e-05 25.6 0.0 0.17 12.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF85534.1 - 6.6e-05 21.9 0.0 0.0014 17.5 0.0 2.3 2 1 0 2 2 2 1 Lycopene cyclase protein SE PF08491.5 EXF85534.1 - 0.00015 20.6 0.0 0.018 13.8 0.0 2.3 2 0 0 2 2 2 2 Squalene epoxidase NAD_binding_8 PF13450.1 EXF85534.1 - 0.0015 18.5 0.1 0.0039 17.1 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EXF85534.1 - 0.0042 15.6 0.4 1.6 7.1 0.0 2.1 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 EXF85534.1 - 0.0085 16.1 0.0 0.018 15.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF85534.1 - 0.0091 14.8 0.2 0.019 13.7 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EXF85534.1 - 0.017 15.0 0.3 0.029 14.2 0.2 1.5 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EXF85534.1 - 0.027 13.0 0.1 2.6 6.5 0.0 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Phenol_hyd_sub PF06099.6 EXF85534.1 - 0.18 11.6 0.3 0.33 10.8 0.2 1.4 1 0 0 1 1 1 0 Phenol hydroxylase subunit SPACA7 PF15307.1 EXF85536.1 - 0.16 12.0 2.2 0.25 11.4 1.5 1.3 1 0 0 1 1 1 0 Sperm acrosome-associated protein 7 COesterase PF00135.23 EXF85538.1 - 6.5e-96 322.1 0.8 1.3e-78 265.0 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF85538.1 - 1e-05 25.2 0.0 2.6e-05 23.9 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF85538.1 - 0.066 12.9 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF85538.1 - 0.071 12.3 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family PTP_N PF12453.3 EXF85538.1 - 0.15 11.6 2.0 2.1 8.0 0.4 3.1 3 0 0 3 3 3 0 Protein tyrosine phosphatase N terminal Sugar_tr PF00083.19 EXF85540.1 - 1.1e-72 245.1 26.4 1.2e-72 244.9 18.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF85540.1 - 1.7e-22 79.6 23.9 2.7e-22 78.9 16.6 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EXF85540.1 - 2.3e-06 26.2 2.1 2.3e-06 26.2 1.4 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein Peptidase_S8 PF00082.17 EXF85541.1 - 1e-41 142.9 3.7 2e-41 142.0 2.5 1.5 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EXF85541.1 - 2.2e-06 28.0 0.0 5.7e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 EXF85541.1 - 0.00018 21.1 0.0 0.00058 19.4 0.0 1.9 1 0 0 1 1 1 1 PA domain DUF3154 PF11351.3 EXF85542.1 - 0.028 14.1 0.5 0.064 13.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3154) MFS_1 PF07690.11 EXF85543.1 - 3e-40 138.0 46.6 1.6e-25 89.5 12.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF85543.1 - 0.00017 20.3 42.5 0.00046 18.9 13.7 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.2 EXF85543.1 - 1.1 9.0 12.1 0.33 10.7 0.9 3.5 4 0 0 4 4 4 0 MFS_1 like family Glyco_hydro_71 PF03659.9 EXF85544.1 - 2.5e-39 134.8 2.9 5e-20 71.3 1.0 2.5 1 1 1 2 2 2 2 Glycosyl hydrolase family 71 Lipase_GDSL PF00657.17 EXF85545.1 - 5.6e-11 42.7 0.3 7.1e-11 42.3 0.2 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EXF85545.1 - 2.6e-05 24.4 1.4 4.2e-05 23.7 1.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family ADH_zinc_N PF00107.21 EXF85547.1 - 4.4e-09 35.9 0.1 7.4e-09 35.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF85547.1 - 6.7e-09 35.4 0.1 3.9e-08 33.0 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain DUF4233 PF14017.1 EXF85548.1 - 0.046 13.6 0.2 0.046 13.6 0.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4233) Chloroa_b-bind PF00504.16 EXF85548.1 - 4.8 7.4 5.8 5.7 7.1 0.0 3.0 2 1 0 3 3 3 0 Chlorophyll A-B binding protein Pec_lyase_C PF00544.14 EXF85549.1 - 2.1e-22 79.5 2.8 3.6e-22 78.8 1.9 1.3 1 0 0 1 1 1 1 Pectate lyase CBM_1 PF00734.13 EXF85549.1 - 1.3e-12 47.1 9.5 1.3e-12 47.1 6.6 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain Beta_helix PF13229.1 EXF85549.1 - 3.7e-05 23.5 13.5 0.00017 21.3 8.0 2.5 1 1 1 2 2 2 2 Right handed beta helix region TFIIA PF03153.8 EXF85549.1 - 1.3 8.8 10.7 1.7 8.4 7.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Methyltransf_23 PF13489.1 EXF85550.1 - 2.2e-21 76.2 0.0 3.8e-21 75.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF85550.1 - 1.4e-10 41.4 0.0 4e-10 40.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF85550.1 - 3.4e-10 39.7 0.0 1.4e-09 37.6 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF85550.1 - 3.7e-10 40.1 0.0 2.5e-09 37.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF85550.1 - 9.6e-09 35.8 0.1 1.3e-07 32.1 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF85550.1 - 0.00012 22.4 0.0 0.00034 20.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF85550.1 - 0.00021 20.4 0.0 0.0023 17.0 0.0 2.3 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EXF85550.1 - 0.0016 17.8 0.0 0.033 13.5 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EXF85550.1 - 0.0055 15.7 0.0 0.041 12.9 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 EXF85550.1 - 0.0071 16.3 0.0 0.036 14.0 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EXF85550.1 - 0.011 15.6 0.1 0.028 14.3 0.1 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase CMAS PF02353.15 EXF85550.1 - 0.021 13.8 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_2 PF00891.13 EXF85550.1 - 0.079 12.1 0.0 0.45 9.6 0.0 1.9 1 1 0 1 1 1 0 O-methyltransferase PrmA PF06325.8 EXF85550.1 - 0.13 11.3 0.0 0.26 10.3 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) F-box-like PF12937.2 EXF85551.1 - 0.062 13.0 0.0 0.21 11.3 0.0 2.0 1 0 0 1 1 1 0 F-box-like FMO-like PF00743.14 EXF85552.1 - 1.2e-24 86.4 0.0 5.5e-20 71.0 0.0 2.1 2 0 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EXF85552.1 - 1.5e-17 64.3 0.0 3.1e-17 63.3 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF85552.1 - 1.7e-11 44.3 0.0 8.2e-10 38.8 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF85552.1 - 2.3e-10 39.9 0.0 1.4e-08 34.1 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EXF85552.1 - 6.9e-09 35.6 0.3 2.8e-07 30.4 0.1 2.6 2 1 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EXF85552.1 - 3.9e-07 29.9 0.0 8.7e-06 25.6 0.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EXF85552.1 - 0.0013 17.9 0.0 0.18 10.8 0.0 2.2 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.19 EXF85552.1 - 0.0018 17.2 0.3 0.079 11.8 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EXF85552.1 - 0.0048 16.0 0.3 0.073 12.1 0.0 2.1 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.12 EXF85552.1 - 0.021 13.9 0.0 0.11 11.5 0.0 2.0 2 0 0 2 2 2 0 Thi4 family DUF498 PF04430.9 EXF85552.1 - 0.056 12.9 0.0 6 6.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) NAD_Gly3P_dh_N PF01210.18 EXF85552.1 - 0.066 12.9 0.0 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.14 EXF85552.1 - 0.075 12.1 0.0 0.86 8.7 0.0 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4124 PF13511.1 EXF85552.1 - 0.12 12.3 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4124) DUF2235 PF09994.4 EXF85553.1 - 2.2e-46 158.4 0.0 3e-46 158.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized alpha/beta hydrolase domain (DUF2235) RhgB_N PF09284.5 EXF85555.1 - 2.7e-91 305.3 0.0 3.7e-91 304.9 0.0 1.2 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal CBM-like PF14683.1 EXF85555.1 - 8.1e-47 158.9 0.0 1.6e-46 158.0 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain III fn3_3 PF14686.1 EXF85555.1 - 7.2e-13 48.4 0.1 1.9e-12 47.0 0.1 1.7 1 0 0 1 1 1 1 Polysaccharide lyase family 4, domain II DPM3 PF08285.6 EXF85556.1 - 1.2e-32 111.5 0.2 1.3e-32 111.4 0.1 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Abhydrolase_3 PF07859.8 EXF85557.1 - 9.6e-62 208.2 0.0 1.2e-61 207.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EXF85557.1 - 3.3e-09 36.2 0.0 5.3e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.23 EXF85557.1 - 1.6e-05 23.8 0.0 0.00016 20.5 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EXF85557.1 - 0.00095 18.9 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ribonuc_L-PSP PF01042.16 EXF85558.1 - 1e-37 128.5 0.0 1.1e-37 128.4 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP TrwC PF08751.6 EXF85558.1 - 0.083 12.3 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 TrwC relaxase MFS_1 PF07690.11 EXF85559.1 - 2.5e-33 115.2 30.3 2.9e-33 115.0 19.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.11 EXF85559.1 - 0.15 10.7 9.3 0.062 11.9 0.3 2.2 2 0 0 2 2 2 0 BT1 family HET PF06985.6 EXF85560.1 - 2.5e-17 63.3 0.0 5.2e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Trp_DMAT PF11991.3 EXF85561.1 - 3.3e-63 214.0 0.0 4.8e-63 213.5 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase Terpene_synth_C PF03936.11 EXF85564.1 - 1e-14 54.4 0.2 1.7e-14 53.7 0.1 1.4 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain XFP PF03894.10 EXF85564.1 - 0.055 13.0 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase FAD-oxidase_C PF02913.14 EXF85565.1 - 3.9e-15 55.8 0.1 5.9e-15 55.2 0.1 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EXF85565.1 - 1.5e-09 37.4 0.6 6.1e-06 25.7 0.0 2.7 2 0 0 2 2 2 2 FAD binding domain AftA_N PF12250.3 EXF85565.1 - 0.15 10.7 0.2 2.8 6.5 0.1 2.1 2 0 0 2 2 2 0 Arabinofuranosyltransferase N terminal ABM PF03992.11 EXF85566.1 - 0.072 13.1 0.4 4.5 7.3 0.4 2.2 2 0 0 2 2 2 0 Antibiotic biosynthesis monooxygenase 4HBT_3 PF13622.1 EXF85567.1 - 2.2e-45 155.4 0.9 2.8e-45 155.0 0.6 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Acyl_CoA_thio PF02551.10 EXF85567.1 - 2.1e-25 88.8 0.0 2e-10 40.4 0.0 4.1 3 1 0 3 3 3 3 Acyl-CoA thioesterase Oxysterol_BP PF01237.13 EXF85568.1 - 1.2e-130 435.1 0.1 4.8e-130 433.1 0.0 2.0 2 0 0 2 2 2 1 Oxysterol-binding protein Ank_2 PF12796.2 EXF85568.1 - 2.2e-18 66.3 0.1 4.7e-12 46.0 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EXF85568.1 - 4.4e-17 60.9 0.1 7.5e-07 28.6 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EXF85568.1 - 2.4e-16 59.3 0.6 2.8e-09 36.9 0.0 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EXF85568.1 - 2.8e-16 59.5 0.0 3.7e-09 36.8 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF85568.1 - 9.5e-15 53.2 0.0 0.00015 21.6 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat PH PF00169.24 EXF85568.1 - 3.9e-11 43.0 0.5 9.7e-11 41.8 0.3 1.7 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EXF85568.1 - 1.1e-07 31.8 1.0 3e-07 30.3 0.7 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain Glyco_hydro_18 PF00704.23 EXF85569.1 - 2.8e-09 36.8 1.2 1.1e-08 34.9 0.8 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 GHL6 PF14871.1 EXF85569.1 - 0.016 15.2 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase 6 B_lectin PF01453.19 EXF85570.1 - 0.00058 19.7 1.5 0.0068 16.2 0.2 2.4 1 1 1 2 2 2 1 D-mannose binding lectin DUF914 PF06027.7 EXF85571.1 - 1.4e-101 339.6 19.9 1.9e-101 339.2 13.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) EamA PF00892.15 EXF85571.1 - 6.4e-06 26.2 33.5 0.00023 21.2 9.1 2.7 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EXF85571.1 - 0.036 12.9 18.3 0.052 12.4 12.7 1.2 1 0 0 1 1 1 0 UAA transporter family TPT PF03151.11 EXF85571.1 - 0.064 12.9 23.8 0.071 12.7 2.1 2.8 3 0 0 3 3 3 0 Triose-phosphate Transporter family FUSC-like PF12805.2 EXF85571.1 - 1.6 7.5 7.7 0.096 11.6 1.0 2.0 2 1 0 2 2 2 0 FUSC-like inner membrane protein yccS CFEM PF05730.6 EXF85573.1 - 4e-10 39.3 13.9 1.1e-09 37.9 9.7 1.8 1 0 0 1 1 1 1 CFEM domain Phage_Gp19 PF09355.5 EXF85573.1 - 2.8 7.7 6.9 48 3.8 4.6 2.6 1 1 0 2 2 2 0 Phage protein Gp19/Gp15/Gp42 DUF3883 PF13020.1 EXF85574.1 - 0.0017 18.0 0.0 0.0037 16.9 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3883) HATPase_c_3 PF13589.1 EXF85575.1 - 0.0029 17.2 0.1 0.0076 15.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PI3Ka PF00613.15 EXF85577.1 - 7e-60 201.3 1.4 1.1e-59 200.7 0.9 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EXF85577.1 - 2.3e-43 148.3 0.0 5.6e-42 143.8 0.0 2.7 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EXF85577.1 - 5.5e-31 107.2 0.0 1e-30 106.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 Nse4_C PF08743.5 EXF85578.1 - 1.8e-34 117.6 0.1 4.4e-34 116.3 0.0 1.7 2 0 0 2 2 2 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EXF85578.1 - 5.2e-17 61.4 0.1 1.8e-16 59.7 0.1 2.0 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DUF4336 PF14234.1 EXF85579.1 - 4.6e-14 52.2 0.0 1e-09 38.0 0.0 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF4336) BTB PF00651.26 EXF85580.1 - 4e-13 49.3 0.0 7.5e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain CNH PF00780.17 EXF85581.1 - 1.1e-82 277.6 0.0 4e-82 275.7 0.0 1.8 2 0 0 2 2 2 1 CNH domain PH_5 PF15405.1 EXF85581.1 - 6.6e-45 152.3 0.0 1.5e-44 151.1 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain RhoGEF PF00621.15 EXF85581.1 - 4e-36 124.5 0.0 9.6e-36 123.3 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain DEP PF00610.16 EXF85581.1 - 1.8e-14 53.1 0.0 3.7e-14 52.2 0.0 1.6 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) PAP2_3 PF14378.1 EXF85581.1 - 0.49 9.8 0.1 1.2 8.6 0.0 1.5 2 0 0 2 2 2 0 PAP2 superfamily ATP-synt_C PF00137.16 EXF85582.1 - 5.6e-19 67.8 35.9 1.2e-16 60.3 4.2 3.1 2 1 1 3 3 3 3 ATP synthase subunit C MFS_1 PF07690.11 EXF85584.1 - 4.6e-36 124.2 65.8 2.4e-33 115.3 34.9 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3272 PF11676.3 EXF85584.1 - 0.049 13.6 1.5 0.15 12.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3272) PI3_PI4_kinase PF00454.22 EXF85585.1 - 5e-49 166.8 0.0 9.6e-49 165.9 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EXF85585.1 - 8.2e-35 120.4 3.5 1.4e-34 119.6 2.4 1.4 1 0 0 1 1 1 1 FAT domain UME PF08064.8 EXF85585.1 - 8.8e-27 93.1 0.0 4.9e-26 90.7 0.0 2.5 2 0 0 2 2 2 1 UME (NUC010) domain FATC PF02260.15 EXF85585.1 - 2.6e-17 61.9 0.5 6.3e-16 57.5 0.0 2.6 2 0 0 2 2 2 1 FATC domain TPR_19 PF14559.1 EXF85585.1 - 0.0038 17.5 6.3 0.058 13.7 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.1 EXF85585.1 - 0.004 17.7 3.3 0.11 13.1 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat CAP_N PF01213.14 EXF85585.1 - 0.013 14.8 1.3 0.018 14.3 0.2 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal zf-PARP PF00645.13 EXF85586.1 - 1.9e-14 53.6 0.8 3.8e-14 52.6 0.6 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region DUF4061 PF13270.1 EXF85586.1 - 0.34 11.0 2.1 0.42 10.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) SKG6 PF08693.5 EXF85588.1 - 0.021 14.1 2.7 0.057 12.7 1.9 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain PFK PF00365.15 EXF85589.1 - 9.7e-164 543.1 0.7 5.7e-119 396.2 1.3 2.1 2 0 0 2 2 2 2 Phosphofructokinase UVR PF02151.14 EXF85589.1 - 0.061 12.8 0.2 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 UvrB/uvrC motif TgMIC1 PF11476.3 EXF85589.1 - 0.069 12.6 0.8 4.5 6.8 0.0 2.4 2 0 0 2 2 2 0 Toxoplasma gondii micronemal protein 1 TgMIC1 His_Phos_2 PF00328.17 EXF85591.1 - 9.7e-129 429.6 0.7 1.5e-128 429.0 0.5 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) RimK PF08443.6 EXF85591.1 - 2.8e-06 26.9 0.0 5.1e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Utp21 PF04192.7 EXF85592.1 - 1.2e-79 266.7 0.0 1.6e-79 266.3 0.0 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EXF85592.1 - 4.4e-22 77.0 18.5 3e-06 26.8 0.6 8.1 8 0 0 8 8 8 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EXF85592.1 - 0.00014 20.3 0.0 0.00024 19.5 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain Nup160 PF11715.3 EXF85592.1 - 0.003 15.7 0.6 8.4 4.3 0.0 3.3 3 0 0 3 3 3 3 Nucleoporin Nup120/160 Pkinase PF00069.20 EXF85593.1 - 1.1e-57 195.1 0.0 1.6e-57 194.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF85593.1 - 4.5e-21 75.0 0.2 8.1e-21 74.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EXF85593.1 - 0.016 14.9 0.0 0.076 12.7 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EXF85593.1 - 0.049 13.2 0.7 0.11 12.0 0.5 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EXF85593.1 - 0.18 11.1 0.0 0.49 9.7 0.0 1.7 1 0 0 1 1 1 0 RIO1 family Pex24p PF06398.6 EXF85594.1 - 6.5e-94 314.6 0.0 7.9e-94 314.3 0.0 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF3292 PF11696.3 EXF85594.1 - 0.078 10.8 0.1 0.11 10.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Reticulon PF02453.12 EXF85594.1 - 0.17 11.4 2.2 0.37 10.3 1.1 1.9 1 1 1 2 2 2 0 Reticulon DUF4395 PF14340.1 EXF85594.1 - 7.6 6.6 8.1 22 5.1 0.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4395) polyprenyl_synt PF00348.12 EXF85595.1 - 1.1e-57 194.8 0.0 1.6e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase CDC14 PF08045.6 EXF85596.1 - 4.1e-95 317.7 0.0 4.7e-95 317.5 0.0 1.0 1 0 0 1 1 1 1 Cell division control protein 14, SIN component SKG6 PF08693.5 EXF85597.1 - 0.35 10.2 2.3 0.73 9.1 1.6 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain APH PF01636.18 EXF85598.1 - 1.5e-08 34.6 6.9 2.2e-06 27.5 4.8 2.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EXF85598.1 - 3.1e-08 32.9 0.0 4.6e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EXF85598.1 - 5.3e-07 29.0 0.0 1.6e-06 27.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF85598.1 - 0.02 13.9 0.0 0.026 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein tyrosine kinase RIO1 PF01163.17 EXF85598.1 - 0.062 12.6 0.0 1.1 8.5 0.0 2.4 2 0 0 2 2 2 0 RIO1 family Choline_kinase PF01633.15 EXF85598.1 - 0.18 11.3 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase Acyl_transf_3 PF01757.17 EXF85599.1 - 2.8e-45 154.6 34.5 3.6e-45 154.2 23.9 1.1 1 0 0 1 1 1 1 Acyltransferase family ALAD PF00490.16 EXF85600.1 - 3.8e-117 390.8 0.0 4.4e-117 390.5 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Mito_carr PF00153.22 EXF85603.1 - 1.1e-52 175.7 1.5 2.9e-19 68.5 0.2 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein RNA_pol_A_bac PF01000.21 EXF85604.1 - 1.7e-33 115.0 0.0 2.8e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EXF85604.1 - 2.8e-14 51.9 0.0 3.7e-14 51.6 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain GrpE PF01025.14 EXF85605.1 - 1.3e-51 174.4 5.8 1.7e-51 174.0 4.0 1.1 1 0 0 1 1 1 1 GrpE DUF334 PF03904.8 EXF85605.1 - 0.026 13.8 0.2 0.039 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Phi_1 PF04674.7 EXF85605.1 - 0.14 11.3 0.1 0.18 10.9 0.1 1.1 1 0 0 1 1 1 0 Phosphate-induced protein 1 conserved region IncA PF04156.9 EXF85605.1 - 4.3 6.8 6.5 15 5.0 4.5 1.8 1 1 0 1 1 1 0 IncA protein RFC1 PF08519.7 EXF85607.1 - 1.3e-56 190.6 0.0 2.7e-56 189.6 0.0 1.6 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.21 EXF85607.1 - 2.7e-13 49.8 0.0 6.2e-13 48.6 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.24 EXF85607.1 - 1.2e-08 35.2 0.2 7.2e-08 32.6 0.1 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EXF85607.1 - 7.8e-06 24.8 0.0 1.5e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein AAA_17 PF13207.1 EXF85607.1 - 6.2e-05 23.8 0.0 6.2e-05 23.8 0.0 3.5 4 0 0 4 4 3 1 AAA domain AAA_22 PF13401.1 EXF85607.1 - 0.00024 21.2 0.0 0.0013 18.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EXF85607.1 - 0.00083 19.6 2.8 0.0009 19.5 0.1 2.6 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EXF85607.1 - 0.001 18.8 0.1 0.0029 17.3 0.1 1.7 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EXF85607.1 - 0.0075 16.2 0.0 0.034 14.1 0.0 2.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.1 EXF85607.1 - 0.012 15.4 0.2 0.051 13.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EXF85607.1 - 0.019 14.9 0.7 0.099 12.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain PTCB-BRCT PF12738.2 EXF85607.1 - 0.054 13.3 0.0 0.14 11.9 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain NTPase_1 PF03266.10 EXF85607.1 - 0.082 12.6 0.4 0.17 11.6 0.0 1.7 2 0 0 2 2 1 0 NTPase Ribosomal_L16 PF00252.13 EXF85608.1 - 5.9e-30 103.7 0.4 7.9e-30 103.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Rep_fac_C PF08542.6 EXF85609.1 - 6.3e-24 83.7 0.1 1.4e-23 82.6 0.1 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EXF85609.1 - 4e-11 42.8 0.0 7.5e-11 41.9 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EXF85609.1 - 1.6e-06 28.3 0.1 3.8e-06 27.1 0.1 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EXF85609.1 - 2.5e-06 27.6 0.6 7.1e-05 22.9 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_16 PF13191.1 EXF85609.1 - 0.0001 22.3 2.4 0.061 13.3 0.0 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 EXF85609.1 - 0.0073 16.1 0.1 0.015 15.1 0.1 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EXF85609.1 - 0.011 15.9 0.0 0.024 14.9 0.0 1.6 1 0 0 1 1 1 0 ABC transporter T4SS-DNA_transf PF02534.9 EXF85609.1 - 0.024 13.2 0.1 0.11 11.0 0.0 1.9 2 0 0 2 2 2 0 Type IV secretory system Conjugative DNA transfer SNF2_N PF00176.18 EXF85609.1 - 0.034 12.9 0.0 0.039 12.7 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain AAA_10 PF12846.2 EXF85609.1 - 0.036 13.5 0.1 1.9 7.8 0.0 2.5 3 0 0 3 3 3 0 AAA-like domain AAA_29 PF13555.1 EXF85609.1 - 0.066 12.7 0.1 0.9 9.1 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EXF85609.1 - 0.086 12.5 0.0 0.26 10.9 0.0 1.8 1 1 0 1 1 1 0 Archaeal ATPase TK PF00265.13 EXF85609.1 - 0.13 11.7 0.6 0.96 8.9 0.5 2.3 2 1 0 2 2 2 0 Thymidine kinase AMP-binding PF00501.23 EXF85610.1 - 2.6e-89 299.4 0.1 3.2e-89 299.2 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EXF85610.1 - 5.6e-22 78.4 0.4 1.1e-19 71.1 0.2 2.8 2 0 0 2 2 2 2 AMP-binding enzyme C-terminal domain Reprolysin_5 PF13688.1 EXF85611.1 - 1e-62 211.6 9.3 1e-62 211.6 6.4 3.0 2 1 1 3 3 3 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.1 EXF85611.1 - 2.2e-53 180.8 2.5 4.7e-53 179.7 1.8 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.1 EXF85611.1 - 8.6e-52 175.6 3.6 2.5e-51 174.1 2.5 1.8 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EXF85611.1 - 3.1e-20 72.9 0.5 3.1e-20 72.9 0.4 2.4 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Disintegrin PF00200.18 EXF85611.1 - 2.1e-18 66.3 32.5 2.1e-18 66.3 22.5 4.8 3 2 1 4 4 4 1 Disintegrin Reprolysin PF01421.14 EXF85611.1 - 4e-05 23.3 9.8 4e-05 23.3 6.8 3.4 2 1 0 2 2 2 1 Reprolysin (M12B) family zinc metalloprotease Pep_M12B_propep PF01562.14 EXF85611.1 - 0.023 14.4 0.2 0.047 13.4 0.1 1.4 1 0 0 1 1 1 0 Reprolysin family propeptide Sensor PF13796.1 EXF85611.1 - 0.047 13.3 0.1 0.11 12.0 0.1 1.7 1 0 0 1 1 1 0 Putative sensor TLD PF07534.11 EXF85613.1 - 1.9e-24 86.2 0.0 4.6e-13 49.3 0.0 2.2 2 0 0 2 2 2 2 TLD Pkinase PF00069.20 EXF85614.1 - 3.2e-74 249.3 0.0 4.4e-74 248.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF85614.1 - 1e-31 109.9 0.0 1.3e-31 109.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF85614.1 - 0.00055 18.9 0.0 0.0011 18.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EXF85614.1 - 0.002 17.2 0.1 0.0033 16.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EXF85614.1 - 0.0099 15.6 0.0 0.014 15.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EXF85614.1 - 0.048 12.4 0.0 0.074 11.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Gag_p6 PF08705.6 EXF85614.1 - 0.085 12.9 0.1 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Gag protein p6 S_100 PF01023.14 EXF85614.1 - 0.1 11.9 0.3 0.36 10.2 0.2 1.9 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain Sec23_trunk PF04811.10 EXF85615.1 - 1e-70 237.9 0.0 1.5e-70 237.3 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EXF85615.1 - 3.5e-26 90.6 0.0 7e-25 86.4 0.0 2.5 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EXF85615.1 - 7.4e-18 64.8 0.0 1.7e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EXF85615.1 - 8e-18 63.7 5.1 1.3e-17 63.0 3.6 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EXF85615.1 - 2.7e-10 39.7 0.0 6.7e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 Gelsolin repeat PTR2 PF00854.16 EXF85616.1 - 0.0066 15.2 0.1 0.0072 15.1 0.1 1.0 1 0 0 1 1 1 1 POT family EI24 PF07264.6 EXF85616.1 - 0.059 12.8 0.0 0.059 12.8 0.0 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) UXS1_N PF11803.3 EXF85616.1 - 0.12 12.0 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 UDP-glucuronate decarboxylase N-terminal FixQ PF05545.6 EXF85616.1 - 0.13 11.9 1.2 0.21 11.2 0.9 1.3 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Fungal_trans_2 PF11951.3 EXF85617.1 - 1.9e-10 39.9 0.1 3.3e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF85617.1 - 1.2e-06 28.3 12.3 2.4e-06 27.3 8.5 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Xpo1 PF08389.7 EXF85618.1 - 1.7e-08 34.5 1.2 0.00051 19.9 0.0 4.2 3 0 0 3 3 3 2 Exportin 1-like protein IBN_N PF03810.14 EXF85618.1 - 0.00063 19.6 0.2 0.0061 16.4 0.0 2.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain WD40 PF00400.27 EXF85619.1 - 1.4e-09 37.4 3.0 0.0027 17.5 0.0 5.5 5 1 0 5 5 5 3 WD domain, G-beta repeat DUF1917 PF08939.5 EXF85620.1 - 9.1e-58 195.8 0.5 1.7e-57 194.9 0.3 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1917) Acetyltransf_1 PF00583.19 EXF85621.1 - 4.6e-20 71.4 0.0 6.5e-20 70.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EXF85621.1 - 3.4e-11 43.2 0.0 5.1e-11 42.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EXF85621.1 - 5.1e-11 42.5 0.0 7.1e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EXF85621.1 - 1.8e-10 41.1 0.0 2.2e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EXF85621.1 - 1e-09 37.9 0.0 1.7e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EXF85621.1 - 4.2e-08 33.2 0.0 5e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EXF85621.1 - 3.7e-07 30.0 0.0 6.7e-07 29.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EXF85621.1 - 0.00078 19.2 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 EXF85621.1 - 0.0019 18.1 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.2 EXF85621.1 - 0.052 12.3 0.0 0.068 11.9 0.0 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase LCAT PF02450.10 EXF85622.1 - 2.7e-98 329.4 0.1 3.5e-98 329.1 0.1 1.1 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 EXF85622.1 - 0.0067 15.7 0.0 0.012 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_6 PF12697.2 EXF85622.1 - 0.02 14.8 0.3 0.05 13.4 0.0 1.9 2 1 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF85622.1 - 0.021 14.5 0.0 0.049 13.3 0.0 1.6 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF1778 PF08681.6 EXF85622.1 - 0.14 12.0 0.0 0.31 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1778) DUF2013 PF09431.5 EXF85623.1 - 4.1e-51 172.4 2.6 4.1e-51 172.4 1.8 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF2013) IBN_N PF03810.14 EXF85623.1 - 0.024 14.5 0.6 0.34 10.8 0.1 2.9 3 1 0 3 3 3 0 Importin-beta N-terminal domain PH PF00169.24 EXF85624.1 - 1.8e-10 40.9 0.0 3.9e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 PH domain Prominin PF05478.6 EXF85624.1 - 0.1 10.1 0.2 0.15 9.5 0.2 1.1 1 0 0 1 1 1 0 Prominin DUF1759 PF03564.10 EXF85624.1 - 0.12 12.1 0.2 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) MFS_1 PF07690.11 EXF85625.1 - 9.3e-30 103.5 48.2 6.6e-29 100.7 33.4 2.1 1 1 0 1 1 1 1 Major Facilitator Superfamily Zip PF02535.17 EXF85625.1 - 4.2 6.2 10.2 2.8 6.8 0.2 2.6 2 0 0 2 2 2 0 ZIP Zinc transporter Gar1 PF04410.9 EXF85626.1 - 1.1e-37 128.9 0.0 1.1e-37 128.9 0.0 2.5 2 1 1 3 3 3 1 Gar1/Naf1 RNA binding region tRNA-synt_2b PF00587.20 EXF85627.1 - 9.2e-44 149.0 0.0 1.4e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EXF85627.1 - 4.5e-21 74.6 0.3 9e-21 73.6 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 EXF85627.1 - 4.2e-11 42.5 0.0 1e-10 41.2 0.0 1.7 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 EXF85627.1 - 5.5e-11 42.1 0.0 1.3e-10 40.9 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain CDP-OH_P_transf PF01066.16 EXF85628.1 - 1.3e-13 51.0 3.0 1.3e-13 51.0 2.1 1.6 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Metallopep PF12044.3 EXF85629.1 - 4.3e-169 562.4 0.0 5.2e-169 562.1 0.0 1.1 1 0 0 1 1 1 1 Putative peptidase family Jacalin PF01419.12 EXF85629.1 - 1.2e-06 28.3 0.0 2.4e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Jacalin-like lectin domain Reprolysin_5 PF13688.1 EXF85629.1 - 0.0046 16.9 0.1 0.0096 15.8 0.1 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_2 PF13574.1 EXF85629.1 - 0.072 13.1 0.1 0.14 12.2 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like DUF1795 PF08786.6 EXF85629.1 - 0.095 12.5 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1795) Whi5 PF08528.6 EXF85630.1 - 3e-12 45.8 0.2 5.7e-12 44.9 0.2 1.5 1 0 0 1 1 1 1 Whi5 like DUF834 PF05754.9 EXF85630.1 - 0.19 11.5 0.5 0.57 10.0 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF834) HEM4 PF02602.10 EXF85631.1 - 6.6e-37 126.9 0.0 8.9e-37 126.5 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Evr1_Alr PF04777.8 EXF85632.1 - 2.9e-30 104.0 0.7 2e-29 101.3 0.3 1.9 2 0 0 2 2 2 1 Erv1 / Alr family TPP_enzyme_N PF02776.13 EXF85633.1 - 1.7e-34 118.7 0.0 2.9e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EXF85633.1 - 2.6e-27 95.2 0.0 5.7e-27 94.1 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EXF85633.1 - 5.1e-16 58.6 0.1 3.8e-15 55.7 0.0 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EXF85633.1 - 0.0017 17.3 0.0 0.0028 16.6 0.0 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase E1_dh PF00676.15 EXF85633.1 - 0.0079 14.9 0.1 0.013 14.2 0.1 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component OCC1 PF15506.1 EXF85633.1 - 0.023 14.5 2.5 6.9 6.6 0.0 3.0 3 0 0 3 3 3 0 OCC1 family THUMP PF02926.12 EXF85634.1 - 1.3e-06 28.3 0.6 1.6e-05 24.7 0.6 2.5 1 1 1 2 2 2 1 THUMP domain SGT1 PF07093.6 EXF85636.1 - 1.2e-142 476.2 32.8 1.5e-141 472.7 22.7 1.9 1 1 0 1 1 1 1 SGT1 protein SMC_N PF02463.14 EXF85637.1 - 7e-24 84.2 0.0 2.9e-23 82.2 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EXF85637.1 - 3.3e-17 63.4 0.1 3.3e-17 63.4 0.1 4.8 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.1 EXF85637.1 - 9.4e-06 25.7 0.0 8.9e-05 22.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EXF85637.1 - 0.00046 19.3 0.1 0.0009 18.3 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain Reo_sigmaC PF04582.7 EXF85637.1 - 0.002 17.3 6.2 0.012 14.8 0.4 3.2 2 2 1 3 3 3 1 Reovirus sigma C capsid protein Spc7 PF08317.6 EXF85637.1 - 0.0021 16.7 3.8 0.0021 16.7 2.6 5.4 4 2 1 6 6 6 1 Spc7 kinetochore protein AAA_29 PF13555.1 EXF85637.1 - 0.0026 17.2 0.0 0.0062 16.0 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EXF85637.1 - 0.0034 17.2 0.0 0.01 15.7 0.0 1.7 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_hinge PF06470.8 EXF85637.1 - 0.0038 17.2 0.0 0.012 15.5 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain ABC_tran PF00005.22 EXF85637.1 - 6.7 7.0 18.4 0.37 11.0 0.5 4.6 3 2 0 3 3 3 0 ABC transporter COQ9 PF08511.6 EXF85638.1 - 1.1e-28 98.5 0.0 1.7e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 COQ9 RRM_1 PF00076.17 EXF85639.1 - 2.8e-46 155.0 0.0 2e-16 59.3 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF85639.1 - 3.1e-37 126.3 0.0 3.6e-13 49.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF85639.1 - 9.1e-21 73.4 0.0 3.8e-06 26.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EXF85639.1 - 0.00014 21.6 0.0 0.82 9.5 0.0 3.4 3 0 0 3 3 3 1 RNA binding motif Limkain-b1 PF11608.3 EXF85639.1 - 0.0004 20.0 0.0 10 5.9 0.0 3.6 3 1 0 3 3 3 2 Limkain b1 ATP-grasp_2 PF08442.5 EXF85639.1 - 0.00049 19.5 0.0 0.013 14.8 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain GRP PF07172.6 EXF85639.1 - 0.02 15.3 13.7 0.02 15.3 9.5 4.0 3 1 1 4 4 4 0 Glycine rich protein family SRP14 PF02290.10 EXF85640.1 - 1.5e-22 79.2 0.0 2.3e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle 14kD protein MIF4G PF02854.14 EXF85641.1 - 5.2e-21 75.0 0.0 7.6e-20 71.2 0.0 2.2 2 0 0 2 2 2 1 MIF4G domain MA3 PF02847.12 EXF85641.1 - 1.6e-10 40.7 0.0 6.6e-10 38.6 0.0 2.2 2 0 0 2 2 2 1 MA3 domain Pyr_redox_dim PF02852.17 EXF85642.1 - 3.5e-40 136.4 0.0 8.8e-40 135.1 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.9 EXF85642.1 - 3.8e-37 128.1 15.3 7.4e-36 123.9 10.6 3.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF85642.1 - 1.3e-24 86.3 11.5 3e-22 78.8 0.5 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF85642.1 - 8.9e-11 41.6 3.3 1.5e-05 24.8 0.4 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_oxidored PF12831.2 EXF85642.1 - 1.5e-10 40.8 7.0 8.8e-10 38.2 0.2 2.5 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EXF85642.1 - 1.2e-09 38.5 0.1 6.5e-06 26.3 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF85642.1 - 1.5e-09 37.1 10.2 2.6e-07 29.8 2.9 3.2 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 EXF85642.1 - 4.1e-09 35.8 17.2 0.00023 20.1 0.8 4.2 3 1 1 4 4 4 3 FAD dependent oxidoreductase GIDA PF01134.17 EXF85642.1 - 5.7e-09 35.3 13.5 6.6e-08 31.8 3.0 2.9 2 2 1 3 3 3 2 Glucose inhibited division protein A HI0933_like PF03486.9 EXF85642.1 - 3.1e-07 29.2 12.3 8.4e-05 21.2 1.4 4.1 4 0 0 4 4 4 2 HI0933-like protein Thi4 PF01946.12 EXF85642.1 - 3.6e-07 29.5 3.4 4.7e-05 22.5 0.1 2.4 2 0 0 2 2 2 2 Thi4 family K_oxygenase PF13434.1 EXF85642.1 - 3.5e-05 22.9 0.1 0.27 10.1 0.0 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.7 EXF85642.1 - 0.00023 20.2 0.8 0.0093 14.9 0.0 2.3 2 0 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.16 EXF85642.1 - 0.00048 19.7 2.5 0.21 11.1 0.1 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.14 EXF85642.1 - 0.015 14.4 10.2 0.6 9.0 1.0 3.3 3 0 0 3 3 3 0 FAD binding domain 3HCDH_N PF02737.13 EXF85642.1 - 0.074 12.7 6.5 0.082 12.5 0.1 2.6 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 EXF85642.1 - 0.16 10.9 0.0 0.31 10.0 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase NAD_binding_7 PF13241.1 EXF85642.1 - 0.56 10.4 4.1 5 7.4 0.1 3.0 2 1 0 2 2 2 0 Putative NAD(P)-binding Trp_halogenase PF04820.9 EXF85642.1 - 1.8 7.0 7.3 0.6 8.6 0.8 2.1 2 0 0 2 2 2 0 Tryptophan halogenase FYVE_2 PF02318.11 EXF85644.1 - 0.0017 18.2 21.8 0.31 10.9 1.9 3.4 3 0 0 3 3 3 3 FYVE-type zinc finger F-box PF00646.28 EXF85646.1 - 8.5e-08 31.6 0.1 3e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EXF85646.1 - 3.2e-07 29.9 0.1 5.8e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like UIM PF02809.15 EXF85646.1 - 1.2 8.9 29.4 0.029 13.9 0.7 4.9 5 0 0 5 5 5 0 Ubiquitin interaction motif DUF756 PF05506.7 EXF85648.1 - 0.043 14.2 0.0 0.072 13.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF756) Ank_2 PF12796.2 EXF85650.1 - 4.7e-101 331.3 0.1 6.6e-16 58.4 0.0 18.6 5 4 11 16 16 16 16 Ankyrin repeats (3 copies) Ank PF00023.25 EXF85650.1 - 9.1e-78 252.4 24.8 1.9e-08 33.7 0.1 28.5 29 2 0 29 29 29 15 Ankyrin repeat Ank_4 PF13637.1 EXF85650.1 - 1.1e-74 245.6 20.9 4e-09 36.7 0.0 26.0 20 7 5 26 26 26 12 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF85650.1 - 9.3e-59 189.5 7.3 3.1e-07 30.0 0.0 25.3 28 0 0 28 28 26 9 Ankyrin repeat Ank_5 PF13857.1 EXF85650.1 - 2.1e-55 183.4 25.6 4.7e-05 23.4 0.0 23.7 22 4 5 27 27 27 11 Ankyrin repeats (many copies) NACHT PF05729.7 EXF85650.1 - 1.1e-05 25.1 0.0 2.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EXF85650.1 - 0.032 14.3 0.0 0.14 12.2 0.0 2.2 2 0 0 2 2 1 0 AAA domain PhoH PF02562.11 EXF85650.1 - 0.15 11.3 0.0 0.34 10.1 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein DUF2075 PF09848.4 EXF85650.1 - 0.25 10.2 0.0 0.48 9.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EXF85650.1 - 0.48 9.2 0.0 2 7.1 0.0 2.0 1 1 0 1 1 1 0 NB-ARC domain DAP3 PF10236.4 EXF85650.1 - 0.78 8.6 0.1 1.6 7.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Asp PF00026.18 EXF85652.1 - 9.6e-07 28.3 0.2 3e-06 26.7 0.1 1.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease Syndecan PF01034.15 EXF85652.1 - 0.21 11.2 0.0 0.51 10.0 0.0 1.5 1 0 0 1 1 1 0 Syndecan domain Flavodoxin_1 PF00258.20 EXF85653.1 - 6.6e-29 100.7 0.0 1e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin FAD_binding_1 PF00667.15 EXF85653.1 - 8.6e-24 84.2 0.1 8.1e-22 77.7 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_1 PF00175.16 EXF85653.1 - 1.3e-08 35.3 0.0 2.3e-06 28.1 0.0 2.5 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_3 PF12641.2 EXF85653.1 - 0.0015 17.9 0.0 0.0037 16.6 0.0 1.6 2 0 0 2 2 2 1 Flavodoxin domain DUF2195 PF09961.4 EXF85654.1 - 0.021 14.6 0.1 0.024 14.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2195) Tyrosinase PF00264.15 EXF85656.1 - 2.1e-41 142.5 0.5 3.3e-41 141.8 0.4 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase AA_permease_2 PF13520.1 EXF85657.1 - 2.3e-81 273.5 35.7 2.9e-81 273.1 24.7 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EXF85657.1 - 1.6e-23 82.8 30.0 2.1e-23 82.4 20.8 1.1 1 0 0 1 1 1 1 Amino acid permease CHZ PF09649.5 EXF85658.1 - 0.00018 20.6 0.9 0.00039 19.5 0.6 1.5 1 0 0 1 1 1 1 Histone chaperone domain CHZ Zn_clus PF00172.13 EXF85660.1 - 0.0013 18.6 5.4 0.0033 17.3 3.8 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain bZIP_2 PF07716.10 EXF85660.1 - 0.43 10.4 5.8 0.79 9.5 4.0 1.4 1 0 0 1 1 1 0 Basic region leucine zipper FAM72 PF14976.1 EXF85661.1 - 0.22 11.3 1.8 0.3 10.9 1.2 1.2 1 0 0 1 1 1 0 FAM72 protein Myticin-prepro PF10690.4 EXF85661.1 - 0.23 11.5 1.7 0.38 10.8 1.2 1.4 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel Peptidase_S8 PF00082.17 EXF85662.1 - 1.8e-36 125.7 6.6 3.2e-36 124.9 4.5 1.5 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EXF85662.1 - 4.6e-12 46.3 0.7 4.4e-11 43.1 0.0 2.6 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) FixG_C PF11614.3 EXF85662.1 - 0.11 12.6 0.0 0.52 10.4 0.0 2.1 2 0 0 2 2 2 0 IG-like fold at C-terminal of FixG, putative oxidoreductase zf-C2H2 PF00096.21 EXF85663.1 - 0.031 14.6 4.6 1.4 9.3 0.0 3.4 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF85663.1 - 0.66 10.4 8.3 1.6 9.2 0.2 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger CUE PF02845.11 EXF85664.1 - 6.9e-07 28.6 0.0 1.2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 CUE domain Ribosomal_S10 PF00338.17 EXF85665.1 - 3.5e-29 100.4 0.4 4.2e-29 100.2 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Fibrillarin_2 PF10113.4 EXF85665.1 - 0.049 11.9 0.0 0.05 11.9 0.0 1.1 1 0 0 1 1 1 0 Fibrillarin-like archaeal protein zf-CCCH PF00642.19 EXF85666.1 - 5.7e-05 22.6 3.1 0.0001 21.8 2.2 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Cellulase PF00150.13 EXF85667.1 - 1.6e-18 66.9 0.3 4.2e-18 65.5 0.2 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) p450 PF00067.17 EXF85668.1 - 6.5e-60 202.9 0.0 8.3e-60 202.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EXF85669.1 - 3.7e-27 94.8 0.1 7.3e-27 93.8 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF85669.1 - 1.8e-07 30.9 12.6 4.3e-07 29.7 8.7 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain RP-C_C PF11800.3 EXF85669.1 - 0.064 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region Peptidase_C12 PF01088.16 EXF85672.1 - 7.5e-62 208.2 0.0 9e-62 208.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 Glyoxalase_2 PF12681.2 EXF85672.1 - 0.014 16.0 0.0 0.032 14.8 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase-like domain SUV3_C PF12513.3 EXF85673.1 - 7.5e-14 50.9 0.2 1.8e-13 49.7 0.1 1.7 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Helicase_C PF00271.26 EXF85673.1 - 7e-10 38.6 0.0 4.1e-09 36.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Synaptobrevin PF00957.16 EXF85674.1 - 2.3e-32 110.4 0.5 3e-32 110.0 0.3 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EXF85674.1 - 5.3e-24 83.5 0.0 9.6e-24 82.7 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain SpoIIAA-like PF11964.3 EXF85674.1 - 0.018 15.3 0.1 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 SpoIIAA-like TAF1D PF15333.1 EXF85675.1 - 0.018 14.8 0.3 0.024 14.4 0.2 1.2 1 0 0 1 1 1 0 TATA box-binding protein-associated factor 1D DUF3533 PF12051.3 EXF85675.1 - 0.037 12.7 1.3 0.039 12.6 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Spt20 PF12090.3 EXF85675.1 - 0.16 11.3 2.7 0.17 11.2 1.9 1.1 1 0 0 1 1 1 0 Spt20 family EPL1 PF10513.4 EXF85675.1 - 0.35 11.1 4.0 0.42 10.8 2.8 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like PAT1 PF09770.4 EXF85675.1 - 0.5 8.5 13.0 0.5 8.5 9.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 EXF85675.1 - 0.5 10.0 7.3 0.59 9.8 5.1 1.0 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MTBP_C PF14920.1 EXF85675.1 - 0.53 9.7 5.4 0.66 9.4 3.7 1.1 1 0 0 1 1 1 0 MDM2-binding ERbeta_N PF12497.3 EXF85675.1 - 3.1 7.6 8.2 5.5 6.8 5.7 1.3 1 0 0 1 1 1 0 Estrogen receptor beta MMR1 PF08505.5 EXF85675.1 - 5.1 7.0 11.6 6.3 6.7 8.0 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein adh_short PF00106.20 EXF85676.1 - 1.2e-12 48.0 0.1 6.5e-12 45.6 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EXF85676.1 - 5.1e-07 29.5 0.0 1.2e-06 28.3 0.0 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EXF85676.1 - 2.8e-05 23.6 0.0 4.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family E1-N PF14463.1 EXF85676.1 - 0.026 14.0 0.1 0.045 13.3 0.1 1.4 1 0 0 1 1 1 0 E1 N-terminal domain G6PD_N PF00479.17 EXF85676.1 - 0.1 12.7 1.2 0.17 12.0 0.9 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain G-patch PF01585.18 EXF85677.1 - 3e-06 26.9 0.3 6.7e-06 25.7 0.2 1.6 1 0 0 1 1 1 1 G-patch domain UL40 PF10682.4 EXF85677.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein of human cytomegalovirus HHV-5 Sec1 PF00995.18 EXF85678.1 - 2.3e-139 465.6 0.0 2.6e-139 465.4 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Apo-CIII PF05778.7 EXF85678.1 - 0.084 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 Apolipoprotein CIII (Apo-CIII) SET PF00856.23 EXF85680.1 - 1.1e-10 42.0 0.0 2.3e-07 31.2 0.0 2.4 2 1 0 2 2 2 2 SET domain Npa1 PF11707.3 EXF85681.1 - 2.5e-78 263.4 0.0 4.7e-78 262.4 0.0 1.5 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal Adaptin_N PF01602.15 EXF85681.1 - 0.0016 16.8 0.1 0.11 10.7 0.0 3.0 3 0 0 3 3 3 1 Adaptin N terminal region DIM1 PF02966.11 EXF85682.1 - 1.5e-70 234.8 0.3 1.7e-70 234.6 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 MOR2-PAG1_N PF14222.1 EXF85683.1 - 1e-216 720.9 0.0 1.6e-216 720.3 0.0 1.3 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.1 EXF85683.1 - 6.6e-93 311.2 0.3 1.6e-92 309.9 0.2 1.7 1 0 0 1 1 1 1 Cell morphogenesis C-terminal MOR2-PAG1_mid PF14228.1 EXF85683.1 - 1.6e-37 128.7 7.5 3.1e-17 61.5 0.1 3.5 2 1 1 3 3 3 3 Cell morphogenesis central region Zip PF02535.17 EXF85683.1 - 0.51 9.2 5.8 0.95 8.4 4.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter HEAT PF02985.17 EXF85683.1 - 2.2 8.5 5.5 13 6.1 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat FAD_binding_1 PF00667.15 EXF85684.1 - 2e-59 200.6 0.0 3.1e-59 200.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EXF85684.1 - 2.7e-32 111.7 0.7 6.3e-32 110.5 0.5 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EXF85684.1 - 3.4e-21 75.8 0.0 2.4e-20 73.1 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EXF85684.1 - 0.014 15.4 0.1 0.051 13.5 0.0 2.1 2 0 0 2 2 2 0 Flavodoxin domain RRM_1 PF00076.17 EXF85685.1 - 2.2e-25 88.0 0.0 2.1e-11 43.2 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF85685.1 - 6.6e-17 61.2 0.0 9.5e-08 31.9 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF85685.1 - 2.9e-05 23.8 0.1 0.23 11.3 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RIO1 PF01163.17 EXF85686.1 - 1.1e-41 142.2 0.1 5.9e-29 100.7 0.0 2.2 2 0 0 2 2 2 2 RIO1 family Rio2_N PF09202.6 EXF85686.1 - 5e-29 100.2 0.1 1.3e-28 98.8 0.1 1.7 2 0 0 2 2 2 1 Rio2, N-terminal APH PF01636.18 EXF85686.1 - 2.8e-08 33.7 0.1 7.1e-05 22.6 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EXF85686.1 - 3.2e-05 23.0 0.0 0.0019 17.3 0.0 2.5 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family SDA1 PF05285.7 EXF85686.1 - 1.9 7.6 14.3 2.9 7.1 9.9 1.2 1 0 0 1 1 1 0 SDA1 Sigma70_ner PF04546.8 EXF85686.1 - 2.8 7.5 10.2 5.7 6.4 7.1 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 EXF85686.1 - 2.9 6.5 16.3 4.2 5.9 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PC_rep PF01851.17 EXF85687.1 - 6.7e-20 70.1 13.9 0.00014 21.8 0.1 8.7 9 0 0 9 9 9 3 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EXF85687.1 - 1.1e-09 38.3 1.5 0.00062 20.0 0.0 4.4 4 1 0 4 4 4 2 HEAT repeats HAND PF09110.6 EXF85687.1 - 0.33 11.3 5.7 0.71 10.2 3.9 1.4 1 0 0 1 1 1 0 HAND MatE PF01554.13 EXF85688.1 - 5.2e-53 178.9 27.6 1.4e-30 106.0 6.5 2.2 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EXF85688.1 - 0.0025 17.6 8.7 0.0025 17.6 6.0 3.7 2 2 2 4 4 4 1 Polysaccharide biosynthesis C-terminal domain NUDIX PF00293.23 EXF85689.1 - 5.8e-29 100.4 0.0 8.2e-29 99.9 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Acetyltransf_7 PF13508.1 EXF85690.1 - 8.5e-11 41.8 0.1 1.5e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EXF85690.1 - 1.3e-07 31.5 0.0 2.2e-07 30.7 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EXF85690.1 - 5e-07 29.6 0.0 8.7e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EXF85690.1 - 0.00087 19.3 0.1 0.0024 17.9 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EXF85690.1 - 0.012 15.4 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.1 EXF85690.1 - 0.024 14.5 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EXF85690.1 - 0.041 13.6 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein RPA_C PF08784.6 EXF85691.1 - 2.8e-18 66.1 0.6 9.2e-18 64.5 0.0 2.1 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.20 EXF85691.1 - 6.3e-09 35.5 0.1 1.5e-08 34.3 0.0 1.6 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain Lon_C PF05362.8 EXF85692.1 - 1.2e-68 230.4 0.6 5.3e-68 228.3 0.3 2.0 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain LON PF02190.11 EXF85692.1 - 7e-27 94.4 0.0 1.6e-26 93.2 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) domain AAA PF00004.24 EXF85692.1 - 1.1e-22 80.6 0.0 2.6e-22 79.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ChlI PF13541.1 EXF85692.1 - 1.5e-09 37.4 0.1 1.6e-08 34.0 0.0 2.5 2 1 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.9 EXF85692.1 - 1.6e-07 31.1 0.0 5.2e-07 29.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.12 EXF85692.1 - 1.4e-05 24.5 0.0 3.2e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 EXF85692.1 - 3.4e-05 23.9 0.1 0.00014 21.9 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_3 PF07726.6 EXF85692.1 - 0.00013 21.6 0.0 0.0003 20.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EXF85692.1 - 0.00033 19.7 0.1 0.00089 18.3 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EXF85692.1 - 0.00046 20.1 0.0 0.0032 17.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EXF85692.1 - 0.00048 20.2 0.0 0.01 15.9 0.0 2.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EXF85692.1 - 0.00052 20.8 0.3 0.0021 18.8 0.0 2.3 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.1 EXF85692.1 - 0.0012 18.5 0.1 0.0052 16.4 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain TIP49 PF06068.8 EXF85692.1 - 0.0013 17.5 0.2 0.0031 16.3 0.0 1.6 2 0 0 2 2 2 1 TIP49 C-terminus AAA_25 PF13481.1 EXF85692.1 - 0.0033 16.8 0.0 0.0096 15.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EXF85692.1 - 0.0063 16.8 10.1 0.21 11.9 0.0 4.0 3 1 1 4 4 3 1 AAA domain AAA_14 PF13173.1 EXF85692.1 - 0.011 15.5 0.0 0.049 13.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EXF85692.1 - 0.013 14.5 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_33 PF13671.1 EXF85692.1 - 0.017 14.9 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EXF85692.1 - 0.027 14.1 0.0 0.076 12.6 0.0 1.8 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 EXF85692.1 - 0.032 13.8 0.0 0.066 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EXF85692.1 - 0.036 14.3 0.0 0.12 12.6 0.0 1.9 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EXF85692.1 - 0.051 13.1 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 G-alpha PF00503.15 EXF85692.1 - 0.059 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit RNA_helicase PF00910.17 EXF85692.1 - 0.085 13.0 0.0 0.3 11.2 0.0 2.0 2 0 0 2 2 1 0 RNA helicase DUF258 PF03193.11 EXF85692.1 - 0.13 11.4 0.0 0.27 10.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Atg14 PF10186.4 EXF85692.1 - 0.36 9.7 5.2 0.78 8.6 3.6 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_11 PF13086.1 EXF85692.1 - 0.52 9.8 3.9 1.3 8.5 0.0 2.3 1 1 1 2 2 2 0 AAA domain SGL PF08450.7 EXF85693.1 - 0.087 12.1 0.0 6.8 5.9 0.0 2.2 1 1 1 2 2 2 0 SMP-30/Gluconolaconase/LRE-like region Lactonase PF10282.4 EXF85694.1 - 3e-74 250.1 0.1 3.6e-74 249.8 0.1 1.0 1 0 0 1 1 1 1 Lactonase, 7-bladed beta-propeller DUF3328 PF11807.3 EXF85695.1 - 5.9e-34 117.6 1.1 7.7e-34 117.2 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3328) Peptidase_S10 PF00450.17 EXF85696.1 - 1.7e-83 281.0 0.3 2.6e-83 280.5 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase adh_short PF00106.20 EXF85697.1 - 1.9e-14 53.8 0.1 1.5e-13 51.0 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF85697.1 - 1.2e-07 31.6 0.0 2.2e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF85697.1 - 6.8e-06 25.6 0.0 9.5e-06 25.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short_C2 PF13561.1 EXF85697.1 - 0.00023 20.9 0.1 0.00035 20.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase AdoHcyase_NAD PF00670.16 EXF85697.1 - 0.04 13.7 0.3 0.14 11.9 0.1 1.8 1 1 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_4 PF07993.7 EXF85697.1 - 0.11 11.3 0.1 0.47 9.3 0.1 2.0 1 1 0 1 1 1 0 Male sterility protein FAD_binding_4 PF01565.18 EXF85698.1 - 5.6e-26 90.6 3.3 1.1e-25 89.7 2.3 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF85698.1 - 1.7e-09 37.4 0.0 5e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 Berberine and berberine like DUF3721 PF12518.3 EXF85698.1 - 0.18 11.3 0.7 0.4 10.3 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function HET PF06985.6 EXF85699.1 - 3.3e-24 85.6 0.0 5.5e-20 71.9 0.0 2.5 2 0 0 2 2 2 2 Heterokaryon incompatibility protein (HET) adh_short_C2 PF13561.1 EXF85700.1 - 3.6e-22 79.3 0.0 4.5e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EXF85700.1 - 1.2e-07 31.7 0.3 1.7e-07 31.3 0.2 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Eno-Rase_NADH_b PF12242.3 EXF85700.1 - 0.0026 17.5 0.1 0.0057 16.4 0.1 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase EF-hand_1 PF00036.27 EXF85701.1 - 1.5e-13 48.9 3.2 3.8e-05 22.6 0.3 4.3 4 0 0 4 4 4 3 EF hand ZZ PF00569.12 EXF85701.1 - 5.3e-11 41.8 7.8 9.1e-11 41.1 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type EF-hand_7 PF13499.1 EXF85701.1 - 2.9e-08 33.7 5.5 5.4e-06 26.4 3.0 3.5 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.1 EXF85701.1 - 6.1e-08 31.9 4.0 0.0015 18.2 0.3 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 EXF85701.1 - 3.4e-05 23.3 3.6 0.14 11.8 0.0 3.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.2 EXF85701.1 - 0.016 14.9 0.2 0.12 12.1 0.0 2.5 2 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand C1_3 PF07649.7 EXF85701.1 - 0.032 14.2 9.0 0.062 13.3 6.2 1.5 1 0 0 1 1 1 0 C1-like domain EF-hand_5 PF13202.1 EXF85701.1 - 0.53 9.7 10.1 0.64 9.4 0.7 3.5 3 0 0 3 3 3 0 EF hand Abhydrolase_6 PF12697.2 EXF85702.1 - 1.7e-26 93.5 0.6 2.2e-26 93.1 0.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF85702.1 - 3.3e-11 43.2 0.1 2.1e-10 40.5 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF85702.1 - 6.3e-10 38.9 0.1 1.6e-09 37.6 0.1 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EXF85702.1 - 7.9e-05 22.1 0.0 0.099 12.0 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Esterase PF00756.15 EXF85702.1 - 0.0032 16.9 0.1 0.0073 15.7 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 EXF85702.1 - 0.052 13.4 0.4 0.26 11.1 0.0 2.4 2 1 0 2 2 2 0 Putative lysophospholipase Peptidase_S9 PF00326.16 EXF85702.1 - 0.054 12.7 0.0 0.21 10.7 0.0 1.9 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase_phd PF10503.4 EXF85702.1 - 0.086 12.0 0.2 0.37 10.0 0.0 1.9 2 0 0 2 2 2 0 Esterase PHB depolymerase PGAP1 PF07819.8 EXF85702.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein NMT_C PF02799.10 EXF85703.1 - 1e-75 253.3 0.0 1.5e-75 252.7 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.14 EXF85703.1 - 4.7e-72 240.8 0.2 1e-71 239.8 0.0 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_9 PF13527.1 EXF85703.1 - 0.0001 22.1 0.2 0.0049 16.7 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF4598 PF15370.1 EXF85703.1 - 0.031 14.5 1.3 0.083 13.1 0.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4598) CMS1 PF14617.1 EXF85703.1 - 0.1 11.6 1.4 0.19 10.7 0.3 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit LZ_Tnp_IS66 PF13007.2 EXF85703.1 - 0.7 10.5 5.5 2.2 8.9 3.8 1.9 1 0 0 1 1 1 0 Transposase C of IS166 homeodomain Abhydrolase_6 PF12697.2 EXF85704.1 - 8.2e-13 48.7 0.1 1.3e-12 48.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF85704.1 - 2.3e-12 46.8 0.2 7.2e-12 45.2 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF85704.1 - 1.7e-07 31.0 0.0 2.9e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EXF85704.1 - 0.0013 18.5 0.3 0.011 15.5 0.2 2.3 2 1 0 2 2 2 1 Putative lysophospholipase Peptidase_S15 PF02129.13 EXF85704.1 - 0.011 15.1 0.0 0.022 14.2 0.0 1.5 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_3 PF07859.8 EXF85704.1 - 0.037 13.5 0.1 0.056 12.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EXF85704.1 - 0.096 12.1 0.2 0.19 11.1 0.1 1.4 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase TLD PF07534.11 EXF85707.1 - 2.7e-31 108.4 0.0 7.6e-31 106.9 0.0 1.8 1 1 0 1 1 1 1 TLD MUG2_C PF08593.5 EXF85707.1 - 2.1e-15 56.6 0.1 6.9e-15 55.0 0.1 2.0 1 0 0 1 1 1 1 Meiotically up-regulated glycoproteins C-terminal HIG_1_N PF04588.8 EXF85708.1 - 4.7e-21 74.2 0.8 9e-21 73.3 0.4 1.6 2 0 0 2 2 2 1 Hypoxia induced protein conserved region PALP PF00291.20 EXF85709.1 - 3.4e-74 249.8 0.9 4.2e-74 249.5 0.6 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.13 EXF85709.1 - 2.3e-42 142.4 0.0 1.7e-21 75.5 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase Ribosomal_L36 PF00444.13 EXF85710.1 - 7.6e-22 77.0 11.3 1.1e-21 76.4 7.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L36 Ribosomal_L35p PF01632.14 EXF85710.1 - 0.047 13.6 1.1 0.16 11.9 0.8 1.9 1 0 0 1 1 1 0 Ribosomal protein L35 Complex1_LYR_1 PF13232.1 EXF85711.1 - 9.2e-20 70.6 0.1 1.1e-19 70.3 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EXF85711.1 - 1.3e-18 66.5 0.5 1.7e-18 66.1 0.4 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.1 EXF85711.1 - 0.0031 17.9 0.0 0.0038 17.6 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Acetyltransf_1 PF00583.19 EXF85712.1 - 1e-14 54.3 0.0 1.5e-14 53.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF85712.1 - 1.5e-07 31.4 0.1 2.5e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EXF85712.1 - 9e-07 29.0 0.0 1.4e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EXF85712.1 - 2.3e-05 24.6 0.2 5.7e-05 23.3 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EXF85712.1 - 0.00025 21.0 0.0 0.00037 20.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EXF85712.1 - 0.00053 19.6 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EXF85712.1 - 0.0025 17.6 0.0 0.0036 17.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EXF85712.1 - 0.039 13.8 0.0 0.078 12.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PLAC8 PF04749.12 EXF85713.1 - 8.6e-25 87.3 14.4 1.2e-24 86.8 10.0 1.2 1 0 0 1 1 1 1 PLAC8 family DUF773 PF05600.7 EXF85713.1 - 4.4 5.9 14.0 5.9 5.5 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF773) DUF3632 PF12311.3 EXF85718.1 - 5.5e-11 42.6 1.0 1.6e-08 34.6 0.7 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF3632) Peroxin-3 PF04882.7 EXF85718.1 - 0.031 12.9 0.2 0.089 11.4 0.0 1.7 2 0 0 2 2 2 0 Peroxin-3 p450 PF00067.17 EXF85719.1 - 6.2e-62 209.6 0.0 7.8e-62 209.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Ferric_reduct PF01794.14 EXF85720.1 - 4.7e-18 65.4 14.6 1.5e-17 63.8 10.1 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EXF85720.1 - 9.2e-16 58.1 0.0 7.8e-15 55.1 0.0 2.1 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EXF85720.1 - 4.5e-10 39.3 0.0 9.7e-06 25.4 0.0 2.4 2 0 0 2 2 2 2 FAD-binding domain NAD_binding_1 PF00175.16 EXF85720.1 - 0.036 14.6 0.0 0.12 12.9 0.0 1.9 1 1 0 1 1 1 0 Oxidoreductase NAD-binding domain GFA PF04828.9 EXF85721.1 - 1.8e-11 43.8 0.1 3.6e-11 42.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme zf-C2H2_4 PF13894.1 EXF85722.1 - 5.9 7.4 8.2 0.42 11.0 0.4 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Glyco_tranf_2_3 PF13641.1 EXF85723.1 - 1.9e-37 129.2 0.0 2.7e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EXF85723.1 - 2e-21 76.6 0.1 2e-21 76.6 0.1 2.4 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.21 EXF85723.1 - 2.2e-12 46.9 0.0 3.8e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.9 EXF85723.1 - 6.7e-12 44.5 4.8 9.9e-09 34.0 0.1 3.6 2 1 2 4 4 4 2 Cellulose synthase Glyco_transf_21 PF13506.1 EXF85723.1 - 7.6e-12 44.8 0.0 1.2e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Chitin_synth_2 PF03142.10 EXF85723.1 - 0.073 11.4 0.0 0.27 9.5 0.0 1.9 2 0 0 2 2 2 0 Chitin synthase PEX11 PF05648.9 EXF85723.1 - 0.078 12.2 0.0 0.12 11.5 0.0 1.2 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) TFIIA PF03153.8 EXF85723.1 - 9.5 6.0 15.2 14 5.4 10.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CBFD_NFYB_HMF PF00808.18 EXF85724.1 - 4.2e-11 42.7 0.0 8.6e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EXF85724.1 - 0.00039 20.4 0.0 0.00065 19.7 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIIA PF03153.8 EXF85724.1 - 0.0013 18.7 20.8 0.0019 18.1 14.4 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF3530 PF12048.3 EXF85724.1 - 1.1 8.1 26.8 0.043 12.7 6.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3530) CDC27 PF09507.5 EXF85724.1 - 5.5 6.1 34.2 0.36 10.0 9.1 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 BTV_NS2 PF04514.7 EXF85724.1 - 8.3 5.1 12.0 14 4.4 8.3 1.4 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Hamartin PF04388.7 EXF85724.1 - 9.4 4.7 13.9 15 4.0 9.6 1.3 1 1 0 1 1 1 0 Hamartin protein SnoaL_2 PF12680.2 EXF85725.1 - 0.00047 20.5 0.0 0.00059 20.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain SnoaL_4 PF13577.1 EXF85725.1 - 0.011 15.6 0.1 0.014 15.2 0.1 1.2 1 0 0 1 1 1 0 SnoaL-like domain DUF1308 PF07000.6 EXF85726.1 - 6.3e-32 110.6 0.0 2.7e-31 108.5 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1308) NAD_binding_2 PF03446.10 EXF85727.1 - 1.3e-71 239.6 5.9 4.6e-38 130.6 1.3 2.9 3 0 0 3 3 3 2 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EXF85727.1 - 1.6e-66 221.8 1.7 1.3e-33 115.6 0.1 2.6 2 0 0 2 2 2 2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase DUF1537 PF07005.6 EXF85727.1 - 3e-25 89.2 9.0 1.1e-24 87.4 5.5 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF1537 F420_oxidored PF03807.12 EXF85727.1 - 6.5e-13 48.9 3.9 2.7e-05 24.5 0.4 5.5 5 1 1 6 6 6 2 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EXF85727.1 - 3.4e-12 45.8 0.0 6.1e-06 25.5 0.0 2.5 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EXF85727.1 - 5.2e-07 29.4 1.2 0.00045 19.9 0.5 2.6 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EXF85727.1 - 0.00046 19.6 3.9 0.06 12.7 0.3 4.0 3 1 0 3 3 3 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ApbA PF02558.11 EXF85727.1 - 0.00047 19.6 1.1 0.088 12.2 0.1 2.9 3 0 0 3 3 3 2 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_C PF03720.10 EXF85727.1 - 0.0094 16.0 0.0 1.2 9.3 0.0 2.7 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain Fungal_trans PF04082.13 EXF85728.1 - 4.6e-08 32.2 0.5 1.1e-07 30.9 0.1 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF85728.1 - 1.7e-06 27.8 7.2 2.7e-06 27.1 5.0 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4503 PF14951.1 EXF85728.1 - 0.059 11.5 1.3 0.095 10.8 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) RHD PF00554.17 EXF85728.1 - 0.11 12.1 0.5 0.21 11.3 0.3 1.3 1 0 0 1 1 1 0 Rel homology domain (RHD) MFS_1 PF07690.11 EXF85729.1 - 1.9e-34 118.9 36.6 1.9e-34 118.9 25.4 1.9 2 0 0 2 2 2 1 Major Facilitator Superfamily RskA PF10099.4 EXF85729.1 - 1.4 8.5 7.3 4.3 7.0 1.1 2.6 2 0 0 2 2 2 0 Anti-sigma-K factor rskA p450 PF00067.17 EXF85731.1 - 5.2e-78 262.6 0.0 7e-78 262.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EXF85731.1 - 5e-33 114.4 0.0 8.6e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EXF85731.1 - 7.4e-24 84.3 0.0 1.8e-23 83.1 0.0 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EXF85731.1 - 2.6e-14 53.7 0.0 7.7e-14 52.1 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EXF85731.1 - 0.0064 16.4 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin domain Abhydrolase_3 PF07859.8 EXF85732.1 - 1.7e-51 174.8 0.0 2.1e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EXF85732.1 - 0.00068 18.4 0.1 0.0019 16.9 0.1 1.6 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EXF85732.1 - 0.00085 19.0 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF85732.1 - 0.02 14.1 0.1 6 6.0 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family AXE1 PF05448.7 EXF85732.1 - 0.063 11.7 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) DLH PF01738.13 EXF85732.1 - 0.14 11.3 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family MFS_1 PF07690.11 EXF85733.1 - 3.3e-17 62.2 49.4 2.7e-15 55.9 30.9 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EXF85733.1 - 4e-05 22.0 7.8 4e-05 22.0 5.4 2.8 3 1 0 3 3 3 2 Fungal trichothecene efflux pump (TRI12) Peptidase_C2 PF00648.16 EXF85734.1 - 2.5e-58 197.4 3.6 4.8e-39 134.1 1.0 2.3 2 0 0 2 2 2 2 Calpain family cysteine protease Peptidase_S10 PF00450.17 EXF85735.1 - 4.3e-76 256.7 0.0 2.7e-40 138.8 0.1 2.1 2 0 0 2 2 2 2 Serine carboxypeptidase Zn_clus PF00172.13 EXF85736.1 - 4e-08 33.0 8.2 7.5e-08 32.1 5.7 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF85736.1 - 0.0029 16.2 0.1 0.0088 14.6 0.1 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain NPP1 PF05630.6 EXF85738.1 - 4.9e-32 111.3 0.0 6.6e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Necrosis inducing protein (NPP1) LysM PF01476.15 EXF85739.1 - 0.00081 19.2 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 LysM domain LRV_FeS PF05484.6 EXF85739.1 - 0.044 13.3 0.0 0.18 11.3 0.0 2.0 2 0 0 2 2 2 0 LRV protein FeS4 cluster Epimerase PF01370.16 EXF85740.1 - 5.3e-07 29.3 0.1 0.00026 20.5 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EXF85740.1 - 6.8e-06 26.3 0.1 2.2e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain 3Beta_HSD PF01073.14 EXF85740.1 - 8.1e-06 24.7 0.0 0.007 15.1 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EXF85740.1 - 0.00039 19.5 0.0 0.00056 18.9 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EXF85740.1 - 0.0005 20.1 0.0 0.00085 19.3 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EXF85740.1 - 0.00072 18.8 0.0 0.0011 18.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.7 EXF85740.1 - 0.0032 16.4 0.0 0.012 14.5 0.0 2.0 1 1 0 1 1 1 1 Male sterility protein Shikimate_DH PF01488.15 EXF85740.1 - 0.0099 15.9 0.0 0.017 15.1 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase adh_short PF00106.20 EXF85740.1 - 0.057 13.3 0.1 0.23 11.3 0.1 2.0 1 1 0 1 1 1 0 short chain dehydrogenase Bac_luciferase PF00296.15 EXF85741.1 - 2.3e-72 243.7 0.4 2.7e-72 243.4 0.3 1.0 1 0 0 1 1 1 1 Luciferase-like monooxygenase DUF2407_C PF13373.1 EXF85742.1 - 1.1 9.2 3.8 2.8 7.8 0.9 2.4 2 0 0 2 2 2 0 DUF2407 C-terminal domain IncA PF04156.9 EXF85742.1 - 1.5 8.3 4.3 4.7 6.7 0.0 2.4 2 0 0 2 2 2 0 IncA protein Bestrophin PF01062.16 EXF85744.1 - 1.3e-46 158.8 0.8 5.7e-44 150.2 0.6 2.1 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Glyco_hydro_3 PF00933.16 EXF85746.1 - 4.1e-70 236.1 0.0 6.8e-70 235.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF85746.1 - 1.9e-60 204.2 0.0 5e-60 202.8 0.0 1.8 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF85746.1 - 2.1e-23 82.0 0.4 4e-23 81.1 0.3 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EXF85746.1 - 6.3e-06 25.8 0.0 1.2e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Glyco_hydro_81 PF03639.8 EXF85747.1 - 0.11 10.4 0.0 0.14 10.0 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 81 MFS_1 PF07690.11 EXF85748.1 - 1.1e-24 86.8 24.3 1.6e-24 86.2 16.8 1.3 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3670 PF12419.3 EXF85748.1 - 0.15 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 SNF2 Helicase protein RPE65 PF03055.10 EXF85749.1 - 5.4e-120 401.2 0.0 6.1e-120 401.0 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein OPT PF03169.10 EXF85750.1 - 1.9e-106 356.9 36.0 2.4e-106 356.6 25.0 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein CVNH PF08881.5 EXF85751.1 - 0.0011 19.1 0.0 0.0063 16.7 0.0 1.8 1 1 0 1 1 1 1 CVNH domain CVNH PF08881.5 EXF85752.1 - 1.7e-06 28.1 0.0 6.9e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 CVNH domain zf-like PF04071.7 EXF85752.1 - 0.19 11.4 2.4 0.22 11.2 1.0 1.7 1 1 0 1 1 1 0 Cysteine-rich small domain His_Phos_1 PF00300.17 EXF85753.1 - 1.8e-18 67.1 0.0 3.8e-18 66.0 0.0 1.6 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) ERCC4 PF02732.10 EXF85754.1 - 5.3e-21 74.8 0.0 9.5e-21 74.0 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain CAF-1_p150 PF11600.3 EXF85754.1 - 3e-05 23.5 15.6 8.3e-05 22.0 10.8 1.8 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Spore_coat_CotO PF14153.1 EXF85754.1 - 0.0023 17.3 4.3 0.0041 16.5 3.0 1.4 1 0 0 1 1 1 1 Spore coat protein CotO SR-25 PF10500.4 EXF85754.1 - 0.0029 17.1 14.7 0.0029 17.1 10.2 2.5 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Ycf1 PF05758.7 EXF85754.1 - 0.0098 13.6 4.5 0.014 13.2 3.1 1.1 1 0 0 1 1 1 1 Ycf1 TMPIT PF07851.8 EXF85754.1 - 0.64 9.0 2.1 1 8.3 1.4 1.2 1 0 0 1 1 1 0 TMPIT-like protein NARP1 PF12569.3 EXF85754.1 - 0.95 8.1 12.1 1.5 7.5 8.4 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Dicty_REP PF05086.7 EXF85754.1 - 1.7 6.2 8.0 3 5.4 5.6 1.3 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein CPSF100_C PF13299.1 EXF85754.1 - 1.9 8.6 7.7 5.2 7.2 5.3 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RR_TM4-6 PF06459.7 EXF85754.1 - 2.7 7.7 13.7 5.2 6.8 9.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RNase_H2-Ydr279 PF09468.5 EXF85754.1 - 3.1 6.9 10.6 8.1 5.5 6.8 1.9 2 0 0 2 2 2 0 Ydr279p protein family (RNase H2 complex component) Borrelia_P83 PF05262.6 EXF85754.1 - 3.5 5.7 13.8 4.9 5.3 9.6 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Peptidase_S49_N PF08496.5 EXF85754.1 - 9 6.0 9.4 17 5.1 6.5 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Kinesin PF00225.18 EXF85757.1 - 3.6e-91 305.3 0.0 3.6e-91 305.3 0.0 3.0 2 1 1 3 3 3 1 Kinesin motor domain Fib_alpha PF08702.5 EXF85757.1 - 0.0086 16.2 5.1 0.0086 16.2 3.5 9.8 8 3 2 10 10 10 6 Fibrinogen alpha/beta chain family DNA_binding_1 PF01035.15 EXF85758.1 - 3e-22 78.1 0.1 3.8e-22 77.8 0.0 1.1 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Abhydrolase_3 PF07859.8 EXF85760.1 - 2.9e-38 131.5 0.0 3.7e-38 131.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EXF85760.1 - 0.00074 19.4 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EXF85760.1 - 0.0064 15.2 2.0 0.065 11.9 1.4 2.1 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S51 PF03575.12 EXF85760.1 - 0.17 11.6 0.5 0.27 10.9 0.3 1.3 1 0 0 1 1 1 0 Peptidase family S51 DUF2782 PF11191.3 EXF85762.1 - 5.4 7.0 5.4 11 6.0 3.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2782) Sulfate_transp PF00916.15 EXF85763.1 - 2.9e-77 259.4 9.7 4.6e-77 258.7 6.7 1.3 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EXF85763.1 - 1.4e-28 98.3 3.9 1.4e-28 98.3 2.7 3.1 4 0 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EXF85763.1 - 1.1e-07 31.2 0.0 2.1e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 STAS domain DUF917 PF06032.7 EXF85764.1 - 8.1e-104 346.9 2.7 1.5e-103 346.0 1.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF917) Hydantoinase_A PF01968.13 EXF85764.1 - 1.8e-53 181.5 4.5 4.9e-52 176.8 1.7 3.1 2 1 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EXF85764.1 - 2e-30 105.5 1.8 7.2e-28 97.2 0.0 2.9 3 0 0 3 3 3 2 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.15 EXF85764.1 - 1.7e-05 24.2 3.9 0.00059 19.2 0.0 3.7 2 1 0 2 2 2 1 BadF/BadG/BcrA/BcrD ATPase family MutL PF13941.1 EXF85764.1 - 2.8e-05 22.6 0.3 0.0044 15.3 0.0 2.4 2 0 0 2 2 2 2 MutL protein StbA PF06406.6 EXF85764.1 - 0.024 13.5 0.0 0.89 8.4 0.0 2.3 2 0 0 2 2 2 0 StbA protein Glyco_hydro_92 PF07971.7 EXF85765.1 - 3.4e-162 540.6 0.0 4.6e-162 540.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 92 GFA PF04828.9 EXF85766.1 - 4e-18 65.1 0.4 6.5e-18 64.4 0.3 1.3 1 0 0 1 1 1 1 Glutathione-dependent formaldehyde-activating enzyme Zn_ribbon_recom PF13408.1 EXF85766.1 - 0.39 11.0 6.2 1.9 8.7 0.3 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain Myticin-prepro PF10690.4 EXF85766.1 - 0.79 9.7 5.2 0.19 11.8 0.4 1.9 1 1 1 2 2 2 0 Myticin pre-proprotein from the mussel zf-NADH-PPase PF09297.6 EXF85766.1 - 2 7.9 10.0 0.18 11.3 0.8 2.5 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain CAP_C PF08603.6 EXF85766.1 - 3.6 6.8 5.7 40 3.4 0.0 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) C terminal Sgf11 PF08209.6 EXF85766.1 - 7.1 6.0 8.2 0.66 9.3 1.2 2.2 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) Sulfatase PF00884.18 EXF85767.1 - 6.7e-65 219.2 0.2 9.8e-65 218.7 0.1 1.3 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.17 EXF85767.1 - 0.0018 17.6 4.1 0.026 13.8 2.8 2.1 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Glyco_hydro_18 PF00704.23 EXF85768.1 - 2e-84 283.9 3.5 2.3e-84 283.7 2.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 PTS_2-RNA PF01885.11 EXF85770.1 - 5.3e-69 231.2 0.0 6.3e-69 231.0 0.0 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family dsrm PF00035.20 EXF85771.1 - 0.15 12.6 0.0 0.41 11.2 0.0 1.9 2 0 0 2 2 2 0 Double-stranded RNA binding motif DUF2361 PF10153.4 EXF85772.1 - 3.9e-32 110.7 11.9 3.9e-32 110.7 8.3 3.2 4 0 0 4 4 4 1 Uncharacterised conserved protein (DUF2361) His_Phos_1 PF00300.17 EXF85774.1 - 7.5e-24 84.6 0.0 9.6e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) RabGAP-TBC PF00566.13 EXF85776.1 - 8.5e-29 100.5 0.3 1.6e-28 99.6 0.2 1.5 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Lyase_1 PF00206.15 EXF85777.1 - 3.8e-21 75.6 0.2 5.7e-21 75.0 0.2 1.2 1 0 0 1 1 1 1 Lyase ADSL_C PF10397.4 EXF85777.1 - 1.2e-15 57.3 0.0 4.2e-15 55.5 0.0 2.0 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminus Pkinase PF00069.20 EXF85780.1 - 2e-58 197.6 0.0 2.9e-58 197.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF85780.1 - 4e-20 71.9 0.0 6.7e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF85780.1 - 2.6e-07 29.8 0.0 5.5e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EXF85780.1 - 0.0023 17.7 0.1 0.0097 15.6 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family PAS_9 PF13426.1 EXF85780.1 - 0.06 13.7 0.0 2.1 8.7 0.0 2.8 2 1 0 2 2 2 0 PAS domain RIO1 PF01163.17 EXF85780.1 - 0.065 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 RIO1 family F-box-like PF12937.2 EXF85781.1 - 3.3e-11 42.7 0.3 9.2e-11 41.3 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EXF85781.1 - 2.2e-09 36.6 0.0 1e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 F-box domain LRR_6 PF13516.1 EXF85781.1 - 1.6e-08 33.7 0.0 0.53 10.5 0.0 6.3 7 0 0 7 7 7 2 Leucine Rich repeat LRR_1 PF00560.28 EXF85781.1 - 2.6e-07 29.7 2.5 1.6 9.0 0.0 6.9 5 2 0 5 5 5 2 Leucine Rich Repeat LRR_8 PF13855.1 EXF85781.1 - 3.8e-06 26.5 1.1 0.038 13.7 0.0 4.0 5 0 0 5 5 5 2 Leucine rich repeat LRR_4 PF12799.2 EXF85781.1 - 0.00037 20.0 3.5 0.019 14.5 0.0 4.5 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) PRANC PF09372.5 EXF85781.1 - 0.05 13.5 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 PRANC domain DUF1762 PF08574.5 EXF85782.1 - 1.8e-09 37.8 11.5 1.8e-09 37.8 8.0 3.2 3 1 1 4 4 4 1 Protein of unknown function (DUF1762) Acyl-CoA_dh_2 PF08028.6 EXF85783.1 - 0.082 13.1 2.7 0.51 10.5 0.5 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase, C-terminal domain PAT1 PF09770.4 EXF85784.1 - 6.2 4.9 19.5 9.4 4.3 13.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-HIT PF04438.11 EXF85785.1 - 0.6 9.8 8.7 1 9.0 6.0 1.3 1 0 0 1 1 1 0 HIT zinc finger MFS_1 PF07690.11 EXF85786.1 - 2e-44 151.7 40.8 5.9e-44 150.2 28.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF85786.1 - 1.4e-15 56.8 7.9 1.4e-15 56.8 5.5 2.7 2 1 1 3 3 3 1 Sugar (and other) transporter Glucosamine_iso PF01182.15 EXF85787.1 - 1.2e-57 194.8 0.0 1.4e-57 194.6 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Methyltransf_23 PF13489.1 EXF85788.1 - 9.2e-17 61.2 0.0 1.5e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF85788.1 - 1.2e-09 38.7 0.0 1.4e-08 35.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF85788.1 - 4.2e-09 36.1 0.0 1.6e-07 31.0 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF85788.1 - 3e-07 30.8 0.0 7.3e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF85788.1 - 0.00012 22.4 0.0 0.001 19.4 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF85788.1 - 0.0034 16.5 0.0 0.36 9.8 0.0 2.8 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EXF85788.1 - 0.0051 17.1 0.0 0.012 15.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EXF85788.1 - 0.0057 16.0 0.0 0.057 12.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EXF85788.1 - 0.0092 15.0 0.0 0.049 12.6 0.0 1.9 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.15 EXF85788.1 - 0.011 14.8 0.0 0.055 12.5 0.0 1.8 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EXF85788.1 - 0.011 14.8 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 EXF85788.1 - 0.021 13.9 0.0 0.031 13.4 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_3 PF01596.12 EXF85788.1 - 0.026 13.5 0.0 5 6.1 0.0 2.3 1 1 1 2 2 2 0 O-methyltransferase FtsJ PF01728.14 EXF85788.1 - 0.035 14.0 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EXF85788.1 - 0.035 14.1 0.0 0.14 12.1 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Dioxygenase_C PF00775.16 EXF85789.1 - 3.6e-55 186.0 0.0 1.5e-54 184.0 0.0 1.9 2 0 0 2 2 2 1 Dioxygenase SUI1 PF01253.17 EXF85789.1 - 2.7e-27 94.3 5.4 5.9e-27 93.2 3.7 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 Dioxygenase_N PF04444.9 EXF85789.1 - 1.5e-15 56.9 0.0 1e-14 54.2 0.0 2.1 2 0 0 2 2 2 1 Catechol dioxygenase N terminus CarboxypepD_reg PF13620.1 EXF85789.1 - 0.017 15.1 0.0 0.046 13.7 0.0 1.7 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain EOS1 PF12326.3 EXF85790.1 - 9.9e-25 86.9 6.5 2.4e-20 72.6 1.2 2.1 1 1 1 2 2 2 2 N-glycosylation protein MBA1 PF07961.6 EXF85791.1 - 8.2e-11 41.1 0.2 1.1e-10 40.7 0.2 1.1 1 0 0 1 1 1 1 MBA1-like protein Tim44 PF04280.10 EXF85791.1 - 6.9e-08 32.6 0.0 2.1e-07 31.0 0.0 1.7 1 1 0 1 1 1 1 Tim44-like domain SSF PF00474.12 EXF85792.1 - 7.3e-08 31.4 34.8 1.1e-06 27.5 24.1 2.2 1 1 0 1 1 1 1 Sodium:solute symporter family Sel1 PF08238.7 EXF85796.1 - 9.2e-41 137.3 36.0 4.3e-07 30.3 0.0 8.1 8 0 0 8 8 8 7 Sel1 repeat FIST_C PF10442.4 EXF85796.1 - 0.099 12.5 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 FIST C domain CBP4 PF07960.6 EXF85797.1 - 5.2e-37 126.3 1.3 6.5e-37 126.0 0.9 1.0 1 0 0 1 1 1 1 CBP4 UPF0258 PF06789.7 EXF85797.1 - 0.018 15.1 0.3 0.022 14.8 0.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) DUF3854 PF12965.2 EXF85797.1 - 0.11 12.1 0.7 0.15 11.6 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) NAC PF01849.13 EXF85798.1 - 5.5e-22 77.0 0.1 2.3e-21 75.0 0.1 1.9 2 0 0 2 2 2 1 NAC domain A_deamin PF02137.13 EXF85799.1 - 4.2e-64 217.0 0.0 4.9e-64 216.8 0.0 1.0 1 0 0 1 1 1 1 Adenosine-deaminase (editase) domain Ribosomal_L24e PF01246.15 EXF85800.1 - 1.3e-30 105.0 0.3 1.3e-30 105.0 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e Redoxin PF08534.5 EXF85801.1 - 7.4e-35 119.6 0.0 8.2e-35 119.4 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EXF85801.1 - 4e-11 42.6 0.1 5.2e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family N6_Mtase PF02384.11 EXF85801.1 - 0.053 12.5 0.0 0.073 12.1 0.0 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase DUF1348 PF07080.6 EXF85802.1 - 1.7e-58 196.4 7.8 2.1e-58 196.1 5.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 EXF85802.1 - 1.9e-05 24.9 1.4 2.5e-05 24.6 0.9 1.3 1 0 0 1 1 1 1 SnoaL-like domain RGS PF00615.14 EXF85804.1 - 0.00015 21.8 0.3 0.026 14.6 0.0 2.3 2 0 0 2 2 2 2 Regulator of G protein signaling domain Pox_A14 PF05767.7 EXF85804.1 - 0.0099 15.8 0.1 0.026 14.4 0.1 1.7 1 0 0 1 1 1 1 Poxvirus virion envelope protein A14 CENP-T PF15511.1 EXF85805.1 - 0.0035 16.6 9.2 0.005 16.1 6.4 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Nop14 PF04147.7 EXF85805.1 - 0.0041 15.1 24.4 0.0051 14.8 16.9 1.1 1 0 0 1 1 1 1 Nop14-like family CDC45 PF02724.9 EXF85805.1 - 0.15 10.0 21.5 0.21 9.5 14.9 1.1 1 0 0 1 1 1 0 CDC45-like protein PPP4R2 PF09184.6 EXF85805.1 - 0.24 10.9 18.7 0.33 10.4 12.9 1.2 1 0 0 1 1 1 0 PPP4R2 BUD22 PF09073.5 EXF85805.1 - 0.27 10.2 21.3 0.37 9.8 14.8 1.1 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 EXF85805.1 - 1.3 7.3 24.2 1.8 6.9 16.8 1.1 1 0 0 1 1 1 0 Daxx Family TFIIA PF03153.8 EXF85805.1 - 1.7 8.4 28.2 2.2 8.1 19.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RRN3 PF05327.6 EXF85805.1 - 2.1 6.3 15.0 2.9 5.9 10.4 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 TRAP_alpha PF03896.11 EXF85805.1 - 2.9 6.8 16.4 4.5 6.1 11.3 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SDA1 PF05285.7 EXF85805.1 - 3.8 6.7 28.5 5.2 6.2 19.7 1.1 1 0 0 1 1 1 0 SDA1 DUF1510 PF07423.6 EXF85805.1 - 5.6 6.2 18.5 8.4 5.7 12.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2348 PF09807.4 EXF85808.1 - 6.4e-08 31.9 0.0 1e-07 31.3 0.0 1.4 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2348) Ribosomal_L37e PF01907.14 EXF85809.1 - 9.8e-13 47.6 3.8 1.9e-12 46.7 2.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e AAA_13 PF13166.1 EXF85810.1 - 0.00018 20.1 9.1 0.00018 20.1 6.3 1.3 1 1 0 1 1 1 1 AAA domain Spc7 PF08317.6 EXF85810.1 - 0.0022 16.7 10.6 0.019 13.6 1.0 2.2 2 0 0 2 2 2 2 Spc7 kinetochore protein NPV_P10 PF05531.7 EXF85810.1 - 0.05 13.8 4.8 0.18 12.0 0.1 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF4201 PF13870.1 EXF85810.1 - 0.12 11.8 14.0 0.36 10.2 1.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF310 PF03750.8 EXF85810.1 - 0.15 12.2 1.5 0.35 11.0 0.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF310) Mannitol_dh_C PF08125.8 EXF85810.1 - 0.16 11.1 3.7 0.27 10.3 1.3 1.9 1 1 1 2 2 2 0 Mannitol dehydrogenase C-terminal domain DUF3726 PF12525.3 EXF85810.1 - 0.26 11.1 2.4 0.28 11.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3726) BLOC1_2 PF10046.4 EXF85810.1 - 0.28 11.3 9.7 0.12 12.4 2.4 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc24 PF08286.6 EXF85810.1 - 0.31 10.7 14.8 0.12 12.0 2.3 3.3 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 Phage_GP20 PF06810.6 EXF85810.1 - 0.32 10.4 20.4 7.5 5.9 2.7 3.8 3 1 0 3 3 3 0 Phage minor structural protein GP20 TMF_DNA_bd PF12329.3 EXF85810.1 - 0.45 10.3 31.1 1.1 9.0 4.8 4.2 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Cob_adeno_trans PF01923.13 EXF85810.1 - 0.45 10.2 8.6 0.12 12.1 0.5 2.5 2 1 1 3 3 3 0 Cobalamin adenosyltransferase IncA PF04156.9 EXF85810.1 - 0.85 9.1 30.8 0.48 10.0 6.6 2.7 2 1 1 3 3 3 0 IncA protein Mod_r PF07200.8 EXF85810.1 - 0.86 9.5 24.5 0.074 12.9 5.6 3.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Allexi_40kDa PF05549.6 EXF85810.1 - 1.8 7.7 5.3 0.71 9.1 1.0 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein DUF342 PF03961.8 EXF85810.1 - 2.1 6.6 11.6 0.27 9.5 3.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Lge1 PF11488.3 EXF85810.1 - 2.1 8.5 12.1 3.4 7.9 0.6 3.4 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 PEARLI-4 PF05278.7 EXF85810.1 - 2.2 7.5 14.2 0.37 10.1 2.5 2.3 2 0 0 2 2 2 0 Arabidopsis phospholipase-like protein (PEARLI 4) DUF4613 PF15390.1 EXF85810.1 - 2.5 6.1 10.0 0.14 10.2 1.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4613) CorA PF01544.13 EXF85810.1 - 3.6 6.5 6.6 6.1 5.7 4.5 1.3 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Laminin_II PF06009.7 EXF85810.1 - 3.6 7.3 15.2 0.23 11.2 1.4 3.0 3 0 0 3 3 3 0 Laminin Domain II DUF4610 PF15384.1 EXF85810.1 - 4.1 6.8 11.6 0.39 10.1 0.5 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4610) DUF1043 PF06295.7 EXF85810.1 - 5.7 6.6 9.5 12 5.5 1.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) ADIP PF11559.3 EXF85810.1 - 6.7 6.5 23.3 1.2 8.9 5.8 2.9 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding YgaB PF14182.1 EXF85810.1 - 7.5 6.8 12.3 2.2 8.5 1.0 3.2 3 1 1 4 4 3 0 YgaB-like protein Fungal_trans PF04082.13 EXF85812.1 - 1.9e-15 56.4 0.8 4.8e-15 55.1 0.2 1.9 2 0 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF85812.1 - 1.7e-09 37.4 11.1 3e-09 36.6 7.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Type_III_YscG PF09477.5 EXF85812.1 - 0.042 13.9 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) Mito_carr PF00153.22 EXF85815.1 - 3.5e-72 238.1 3.2 4.7e-24 83.9 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein Zn_clus PF00172.13 EXF85816.1 - 0.0094 15.8 10.6 0.016 15.1 7.3 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain LSM PF01423.17 EXF85817.1 - 3.2e-15 55.4 0.2 4.3e-15 55.0 0.1 1.2 1 0 0 1 1 1 1 LSM domain FoP_duplication PF13865.1 EXF85817.1 - 3.9 7.9 15.4 7.6 7.0 10.6 1.6 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Pkinase PF00069.20 EXF85818.1 - 8.1e-06 25.1 0.0 1.4e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain UBA_4 PF14555.1 EXF85819.1 - 2.6e-10 39.6 0.0 5.2e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EXF85819.1 - 9.2e-07 28.8 0.0 4.2e-06 26.7 0.0 2.2 2 1 0 2 2 2 1 UBX domain SUFU_C PF12470.3 EXF85819.1 - 0.055 13.0 0.8 0.086 12.4 0.5 1.3 1 0 0 1 1 1 0 Suppressor of Fused Gli/Ci N terminal binding domain DUF612 PF04747.7 EXF85819.1 - 0.082 11.7 10.6 0.13 11.1 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF612 GAT PF03127.9 EXF85821.1 - 1.6e-17 63.3 1.0 4.1e-17 61.9 0.3 1.9 2 0 0 2 2 2 1 GAT domain VHS PF00790.14 EXF85821.1 - 0.00069 19.2 0.0 0.0021 17.7 0.0 1.8 2 0 0 2 2 2 1 VHS domain HET PF06985.6 EXF85822.1 - 2e-09 37.7 0.0 4.4e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) UIM PF02809.15 EXF85822.1 - 0.0083 15.6 3.1 6.6 6.5 0.1 3.8 3 0 0 3 3 3 2 Ubiquitin interaction motif TMEM240 PF15207.1 EXF85823.1 - 0.15 11.6 0.7 0.19 11.2 0.5 1.1 1 0 0 1 1 1 0 TMEM240 family F-box PF00646.28 EXF85824.1 - 0.0025 17.4 0.1 0.015 14.9 0.1 2.4 1 0 0 1 1 1 1 F-box domain Histone PF00125.19 EXF85825.1 - 8.5e-26 89.8 0.0 1.1e-25 89.5 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EXF85825.1 - 1.3e-05 25.1 0.0 1.7e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Complex1_LYR PF05347.10 EXF85826.1 - 5.9e-09 35.5 2.7 9.6e-09 34.9 1.8 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EXF85826.1 - 1e-05 25.6 1.5 1.6e-05 24.9 1.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Ribosomal_S4e PF00900.15 EXF85827.1 - 5.6e-31 106.0 0.6 1.3e-30 104.8 0.1 1.8 2 0 0 2 2 2 1 Ribosomal family S4e RS4NT PF08071.7 EXF85827.1 - 2.8e-18 65.4 3.0 6e-18 64.4 2.1 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain KOW PF00467.24 EXF85827.1 - 4e-05 23.1 1.6 4e-05 23.1 1.1 3.0 3 0 0 3 3 3 1 KOW motif S4 PF01479.20 EXF85827.1 - 0.00012 21.4 0.0 0.00026 20.3 0.0 1.6 1 0 0 1 1 1 1 S4 domain Myb_DNA-binding PF00249.26 EXF85828.1 - 6.1e-11 42.2 0.1 0.00015 21.7 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EXF85828.1 - 1e-09 38.3 0.0 0.0022 18.0 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain DUF2718 PF10918.3 EXF85828.1 - 0.084 12.9 1.3 4.8 7.2 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2718) Myb_DNA-bind_6 PF13921.1 EXF85830.1 - 0.071 13.2 0.0 0.23 11.5 0.0 1.9 1 0 0 1 1 1 0 Myb-like DNA-binding domain PPR_1 PF12854.2 EXF85830.1 - 0.94 9.0 2.7 0.43 10.0 0.1 1.8 2 0 0 2 2 2 0 PPR repeat Septin PF00735.13 EXF85831.1 - 8.9e-33 113.5 0.0 8.8e-12 44.6 0.0 3.1 3 0 0 3 3 3 3 Septin Miro PF08477.8 EXF85831.1 - 0.0081 16.6 0.0 0.024 15.1 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_23 PF13476.1 EXF85831.1 - 0.015 15.6 0.1 0.015 15.6 0.1 1.8 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EXF85831.1 - 0.022 14.2 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EXF85831.1 - 0.022 14.7 0.0 0.061 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.1 EXF85831.1 - 0.047 13.2 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EXF85831.1 - 0.14 11.7 0.0 0.34 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.18 EXF85831.1 - 0.16 11.7 1.4 1.8 8.3 0.0 2.8 3 0 0 3 3 3 0 Dynamin family AAA_17 PF13207.1 EXF85831.1 - 0.18 12.6 2.1 0.23 12.3 0.1 2.3 2 2 0 2 2 2 0 AAA domain ABC1 PF03109.11 EXF85833.1 - 4.4e-22 78.2 0.1 1.2e-21 76.8 0.0 1.8 2 0 0 2 2 2 1 ABC1 family APH PF01636.18 EXF85833.1 - 3.1e-05 23.8 0.0 7.5e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family SUR7 PF06687.7 EXF85834.1 - 9.5e-29 100.4 8.7 1.2e-28 100.1 6.0 1.1 1 0 0 1 1 1 1 SUR7/PalI family 7TM_GPCR_Srd PF10317.4 EXF85834.1 - 0.7 8.8 7.1 0.71 8.8 4.3 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd NfeD PF01957.13 EXF85834.1 - 2.6 8.1 9.5 0.3 11.2 2.3 2.4 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding Adaptin_N PF01602.15 EXF85836.1 - 2.7e-113 379.0 0.7 3.4e-113 378.7 0.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EXF85836.1 - 2.1e-56 189.9 4.8 4.4e-56 188.8 3.3 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EXF85836.1 - 2.3e-15 56.6 0.5 2.5e-05 24.4 0.1 5.6 2 1 3 5 5 5 3 HEAT repeats CLASP_N PF12348.3 EXF85836.1 - 0.0003 20.2 3.8 0.0039 16.5 0.2 3.2 3 0 0 3 3 3 1 CLASP N terminal HEAT_PBS PF03130.11 EXF85836.1 - 0.0018 18.5 0.1 1.2 9.7 0.0 4.0 3 0 0 3 3 3 1 PBS lyase HEAT-like repeat HEAT PF02985.17 EXF85836.1 - 0.07 13.2 7.0 2 8.7 0.2 4.9 5 0 0 5 5 5 0 HEAT repeat Alpha_adaptin_C PF02296.11 EXF85836.1 - 0.091 12.7 0.0 0.45 10.4 0.0 2.3 2 0 0 2 2 2 0 Alpha adaptin AP2, C-terminal domain HEAT_EZ PF13513.1 EXF85836.1 - 0.34 11.4 3.4 0.93 10.0 0.7 2.9 2 0 0 2 2 2 0 HEAT-like repeat CDP-OH_P_transf PF01066.16 EXF85837.1 - 3e-16 59.5 2.4 3e-16 59.5 1.6 2.5 3 1 0 3 3 3 1 CDP-alcohol phosphatidyltransferase bZIP_1 PF00170.16 EXF85838.1 - 3.7e-08 33.1 16.5 8.4e-08 32.0 11.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor BLOC1_2 PF10046.4 EXF85838.1 - 0.02 15.0 1.7 0.049 13.7 1.2 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 V_ATPase_I PF01496.14 EXF85838.1 - 0.034 12.0 2.2 0.041 11.7 1.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family bZIP_Maf PF03131.12 EXF85838.1 - 0.044 14.0 15.7 0.039 14.2 9.9 1.6 1 1 0 1 1 1 0 bZIP Maf transcription factor CCDC155 PF14662.1 EXF85838.1 - 0.059 12.9 9.5 0.088 12.3 6.6 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF641 PF04859.7 EXF85838.1 - 0.072 12.8 5.8 0.11 12.2 4.0 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DivIC PF04977.10 EXF85838.1 - 0.1 12.0 5.0 0.28 10.7 3.5 1.7 1 0 0 1 1 1 0 Septum formation initiator ADIP PF11559.3 EXF85838.1 - 0.1 12.4 12.1 0.19 11.5 8.4 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding FlaC_arch PF05377.6 EXF85838.1 - 0.16 11.8 2.9 0.31 10.9 2.0 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) bZIP_2 PF07716.10 EXF85838.1 - 0.24 11.2 19.9 1.2 9.0 13.8 2.0 1 1 0 1 1 1 0 Basic region leucine zipper Glutaredoxin2_C PF04399.8 EXF85838.1 - 0.32 10.5 2.9 0.59 9.7 2.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain NAM-associated PF14303.1 EXF85838.1 - 0.38 11.0 14.1 0.56 10.5 9.8 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain DUF812 PF05667.6 EXF85838.1 - 0.43 9.0 10.6 0.56 8.6 7.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) LMSTEN PF07988.7 EXF85838.1 - 0.81 9.0 6.5 16 4.9 0.6 3.0 1 1 1 2 2 2 0 LMSTEN motif DUF972 PF06156.8 EXF85838.1 - 1.4 9.2 8.4 0.21 11.9 2.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF972) IncA PF04156.9 EXF85838.1 - 4.3 6.8 6.2 6 6.4 4.3 1.2 1 0 0 1 1 1 0 IncA protein APG6 PF04111.7 EXF85838.1 - 5.6 5.9 9.6 7.6 5.4 6.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Bap31 PF05529.7 EXF85838.1 - 8.6 5.7 6.6 13 5.1 4.6 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like PAT1 PF09770.4 EXF85838.1 - 9.9 4.2 28.5 12 3.9 19.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Trp_DMAT PF11991.3 EXF85840.1 - 2.4e-92 309.9 0.0 2.9e-92 309.6 0.0 1.1 1 0 0 1 1 1 1 Tryptophan dimethylallyltransferase DUF2062 PF09835.4 EXF85841.1 - 0.012 15.2 0.1 0.02 14.4 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2062) Zip PF02535.17 EXF85842.1 - 0.21 10.5 0.4 0.32 9.9 0.3 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter Kinesin PF00225.18 EXF85843.1 - 1.5e-115 385.4 0.0 2e-115 385.0 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Herpes_UL14 PF03580.9 EXF85843.1 - 0.0051 16.6 3.4 0.013 15.2 2.4 1.7 1 0 0 1 1 1 1 Herpesvirus UL14-like protein HET PF06985.6 EXF85845.1 - 3.3e-19 69.4 9.8 6.3e-17 62.0 6.8 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) zf-C2H2 PF00096.21 EXF85845.1 - 0.00016 21.8 7.6 0.28 11.5 0.1 3.9 3 0 0 3 3 3 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF85845.1 - 0.049 13.9 6.6 0.35 11.3 0.0 3.6 3 0 0 3 3 3 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.3 EXF85845.1 - 0.085 13.0 2.4 8.6 6.6 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding F-box-like PF12937.2 EXF85846.1 - 0.0002 21.0 1.0 0.0006 19.4 0.7 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EXF85846.1 - 0.0098 15.5 0.4 0.031 13.9 0.3 1.8 1 0 0 1 1 1 1 F-box domain UQ_con PF00179.21 EXF85848.1 - 1.3e-10 40.8 0.0 2.5e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TRCF PF03461.10 EXF85848.1 - 0.0036 17.2 0.0 0.0075 16.2 0.0 1.4 1 0 0 1 1 1 1 TRCF domain F-box PF00646.28 EXF85848.1 - 0.023 14.3 0.4 0.054 13.1 0.3 1.6 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.2 EXF85848.1 - 0.026 14.2 0.3 0.063 13.0 0.2 1.6 1 0 0 1 1 1 0 F-box-like DUF3844 PF12955.2 EXF85851.1 - 8.9e-33 112.4 3.1 1.8e-32 111.4 2.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3844) NTR2 PF15458.1 EXF85852.1 - 2.6e-74 249.6 20.0 2.6e-74 249.6 13.8 1.7 2 0 0 2 2 2 1 Nineteen complex-related protein 2 TMF_TATA_bd PF12325.3 EXF85852.1 - 0.005 16.5 0.3 0.005 16.5 0.2 2.6 3 0 0 3 3 3 1 TATA element modulatory factor 1 TATA binding CK2S PF15011.1 EXF85852.1 - 0.012 15.4 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Casein Kinase 2 substrate LSM PF01423.17 EXF85853.1 - 6.9e-19 67.1 0.8 8e-19 66.9 0.5 1.0 1 0 0 1 1 1 1 LSM domain Rhodanese PF00581.15 EXF85854.1 - 1.4e-10 41.4 0.0 2e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain Amino_oxidase PF01593.19 EXF85855.1 - 5.6e-59 200.4 0.0 6.9e-59 200.0 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EXF85855.1 - 1.2e-08 34.8 0.4 3.2e-08 33.4 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EXF85855.1 - 0.00027 21.0 0.5 0.00063 19.8 0.3 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF85855.1 - 0.00055 18.9 0.2 0.0014 17.5 0.1 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF85855.1 - 0.00055 18.8 0.0 0.00084 18.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.14 EXF85855.1 - 0.0051 15.9 0.6 0.011 14.8 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EXF85855.1 - 0.016 13.7 0.0 0.03 12.8 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.12 EXF85855.1 - 0.034 13.2 0.1 0.06 12.4 0.1 1.3 1 0 0 1 1 1 0 Thi4 family Pyr_redox PF00070.22 EXF85855.1 - 0.18 12.2 0.5 0.65 10.4 0.2 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF85856.1 - 2e-59 201.2 0.1 2.3e-59 201.0 0.1 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF85856.1 - 2.1e-05 24.4 0.1 7.4e-05 22.7 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EXF85856.1 - 4.7e-05 23.5 0.0 0.29 11.1 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF85856.1 - 0.0022 17.1 0.0 0.0037 16.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 EXF85856.1 - 0.0026 17.5 0.1 0.057 13.2 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EXF85856.1 - 0.022 13.2 0.0 0.27 9.6 0.0 2.0 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.22 EXF85856.1 - 0.053 13.9 0.0 1.8 9.0 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF85856.1 - 0.059 12.2 0.0 0.12 11.2 0.0 1.5 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_6 PF00970.19 EXF85857.1 - 2.1e-07 30.9 0.0 4.3e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain Globin PF00042.17 EXF85857.1 - 4.2e-07 30.2 0.0 7.7e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Globin NAD_binding_1 PF00175.16 EXF85857.1 - 7.2e-05 23.3 0.0 0.00023 21.6 0.0 1.9 2 1 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EXF85857.1 - 0.0069 16.3 0.1 0.027 14.3 0.0 2.0 3 0 0 3 3 3 1 Ferric reductase NAD binding domain PA14_2 PF10528.4 EXF85858.1 - 8.4e-26 90.1 7.4 9.6e-18 64.1 1.8 2.8 2 0 0 2 2 2 2 GLEYA domain PA14 PF07691.7 EXF85858.1 - 2.1e-17 63.1 1.2 1e-08 34.9 0.2 3.0 3 0 0 3 3 3 2 PA14 domain Gly_rich PF12810.2 EXF85858.1 - 3 7.3 78.7 0.39 10.2 50.6 2.5 2 1 0 2 2 2 0 Glycine rich protein FAD_binding_3 PF01494.14 EXF85859.1 - 3.9e-19 68.9 0.6 7e-14 51.6 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EXF85859.1 - 8e-08 31.5 0.1 4e-05 22.6 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF85859.1 - 2.2e-05 24.3 2.6 2.5e-05 24.1 0.9 1.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF85859.1 - 0.00045 20.1 0.6 0.001 18.9 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF85859.1 - 0.00056 18.8 2.1 0.00092 18.1 1.5 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EXF85859.1 - 0.0031 17.8 1.0 0.01 16.1 0.7 2.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EXF85859.1 - 0.012 15.2 0.6 0.03 13.9 0.1 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.17 EXF85859.1 - 0.024 13.5 0.8 0.024 13.5 0.6 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EXF85859.1 - 0.024 13.2 0.8 0.13 10.8 0.5 2.0 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.9 EXF85859.1 - 0.048 12.1 0.7 0.093 11.1 0.5 1.5 1 0 0 1 1 1 0 HI0933-like protein Amino_oxidase PF01593.19 EXF85859.1 - 0.063 12.3 1.4 0.084 11.9 0.2 1.7 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase ApbA PF02558.11 EXF85859.1 - 0.097 12.1 0.8 0.19 11.1 0.5 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.2 EXF85859.1 - 0.1 11.6 1.2 0.17 10.9 0.8 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF85859.1 - 0.28 10.0 0.7 12 4.6 0.2 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein MFS_1 PF07690.11 EXF85860.1 - 1.3e-25 89.9 38.3 1e-23 83.6 24.4 2.4 2 0 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF85860.1 - 8e-23 80.4 22.9 1.1e-22 79.9 15.9 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) PIRT PF15099.1 EXF85860.1 - 0.053 12.7 0.1 0.18 11.0 0.1 1.9 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family adh_short_C2 PF13561.1 EXF85862.1 - 1e-08 35.2 0.0 2.9e-07 30.5 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EXF85862.1 - 1.8e-06 27.9 0.3 3.1e-06 27.1 0.2 1.4 1 1 0 1 1 1 1 short chain dehydrogenase Lon_C PF05362.8 EXF85862.1 - 0.041 13.1 0.8 0.082 12.1 0.2 1.6 2 0 0 2 2 2 0 Lon protease (S16) C-terminal proteolytic domain p450 PF00067.17 EXF85863.1 - 1.6e-54 185.2 0.0 2e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EXF85864.1 - 1e-16 61.3 2.0 3e-10 40.2 0.1 2.8 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.1 EXF85864.1 - 6e-12 45.8 0.0 2.3e-11 43.9 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF85864.1 - 0.00094 18.8 2.0 0.0022 17.6 0.3 2.2 2 1 0 2 2 2 1 KR domain Pyr_redox PF00070.22 EXF85864.1 - 0.16 12.3 1.0 0.44 10.9 0.7 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase p450 PF00067.17 EXF85865.1 - 1.4e-52 178.8 0.0 1.9e-52 178.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Clathrin PF00637.15 EXF85866.1 - 3.1e-23 81.9 4.5 3.1e-22 78.7 0.9 2.7 3 0 0 3 3 3 1 Region in Clathrin and VPS VPS11_C PF12451.3 EXF85866.1 - 1.3e-19 69.7 0.1 5.1e-19 67.8 0.0 2.0 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.1 EXF85866.1 - 0.0053 16.5 8.6 0.014 15.2 6.0 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EXF85866.1 - 0.0061 16.2 7.1 0.014 15.1 4.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_1 PF14446.1 EXF85866.1 - 0.053 13.2 3.5 0.14 11.9 2.5 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-Apc11 PF12861.2 EXF85866.1 - 0.17 11.7 1.6 0.48 10.3 1.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EXF85866.1 - 0.23 11.6 3.6 0.56 10.3 2.5 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EXF85866.1 - 0.27 11.2 12.1 0.078 13.0 5.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EXF85866.1 - 2.6 7.7 11.8 0.57 9.8 5.2 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.20 EXF85867.1 - 2.8e-51 174.1 0.2 1.3e-35 122.7 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EXF85867.1 - 9.2e-22 77.3 0.8 3.9e-20 72.0 0.3 3.1 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF85867.1 - 4.2e-05 22.6 0.0 0.00015 20.8 0.0 1.7 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EXF85867.1 - 0.0026 17.5 0.3 0.013 15.1 0.1 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family SAP30_Sin3_bdg PF13867.1 EXF85869.1 - 6.5e-14 51.5 1.6 5e-12 45.4 0.2 2.4 2 0 0 2 2 2 2 Sin3 binding region of histone deacetylase complex subunit SAP30 PPP5 PF08321.7 EXF85869.1 - 0.14 12.1 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 PPP5 TPR repeat region CTDII PF01556.13 EXF85870.1 - 7.5e-29 99.4 1.8 1.7e-22 79.1 0.1 3.5 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ PF00226.26 EXF85870.1 - 1.8e-24 85.1 1.2 3.4e-24 84.3 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EXF85870.1 - 1.5e-10 40.9 21.1 2.9e-10 40.0 14.6 1.5 1 0 0 1 1 1 1 DnaJ central domain BRO1 PF03097.13 EXF85871.1 - 2.6e-129 431.2 0.7 2.6e-129 431.2 0.5 2.5 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EXF85871.1 - 4.7e-95 317.9 18.3 9.5e-95 316.9 12.7 1.5 1 0 0 1 1 1 1 ALIX V-shaped domain binding to HIV DUF4407 PF14362.1 EXF85871.1 - 5.9 5.7 20.1 0.0068 15.3 4.7 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) M_domain PF12938.2 EXF85872.1 - 0.19 11.4 1.5 0.27 11.0 1.1 1.2 1 0 0 1 1 1 0 M domain of GW182 Ank_2 PF12796.2 EXF85873.1 - 1.3e-36 124.8 0.1 1.8e-11 44.2 0.0 4.2 3 1 0 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.25 EXF85873.1 - 2.6e-28 96.3 8.6 5.4e-05 22.7 0.1 9.0 9 0 0 9 9 9 6 Ankyrin repeat Ank_4 PF13637.1 EXF85873.1 - 3.1e-24 84.8 0.3 0.00014 22.3 0.0 7.3 5 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF85873.1 - 2.3e-17 61.3 2.7 0.01 16.0 0.0 8.1 8 0 0 8 8 8 4 Ankyrin repeat Ank_5 PF13857.1 EXF85873.1 - 3.6e-14 52.4 3.6 0.053 13.7 0.1 6.5 3 1 3 6 6 6 5 Ankyrin repeats (many copies) NACHT PF05729.7 EXF85873.1 - 5.3e-06 26.1 0.1 1.2e-05 24.9 0.1 1.6 1 0 0 1 1 1 1 NACHT domain KAP_NTPase PF07693.9 EXF85873.1 - 0.005 15.8 0.1 0.0091 15.0 0.0 1.4 1 0 0 1 1 1 1 KAP family P-loop domain DUF2236 PF09995.4 EXF85874.1 - 1.2e-06 27.9 0.5 4.7e-06 26.0 0.1 2.2 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2236) DUF2116 PF09889.4 EXF85874.1 - 0.17 11.7 1.1 0.29 10.9 0.8 1.3 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) FMN_dh PF01070.13 EXF85875.1 - 4.7e-120 400.6 0.1 6.1e-120 400.3 0.1 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase Cyt-b5 PF00173.23 EXF85875.1 - 5.5e-23 80.5 0.0 1.1e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Glu_synthase PF01645.12 EXF85875.1 - 4.5e-07 29.1 0.1 8.5e-07 28.2 0.0 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase IMPDH PF00478.20 EXF85875.1 - 0.00047 19.1 0.7 0.0032 16.4 0.1 2.1 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain NMO PF03060.10 EXF85875.1 - 0.0071 15.5 0.9 0.011 14.8 0.6 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase His_biosynth PF00977.16 EXF85875.1 - 0.0072 15.6 1.2 0.48 9.6 0.1 2.3 1 1 0 2 2 2 1 Histidine biosynthesis protein DUF561 PF04481.7 EXF85875.1 - 0.063 12.2 0.1 0.51 9.2 0.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF561) ThiG PF05690.9 EXF85875.1 - 0.066 12.2 0.2 6.2 5.8 0.0 2.2 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG PSDC PF12588.3 EXF85876.1 - 6.9e-34 116.4 0.0 1.3e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 Phophatidylserine decarboxylase PS_Dcarbxylase PF02666.10 EXF85876.1 - 3e-27 95.2 0.0 4.2e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Sensor PF13796.1 EXF85877.1 - 0.087 12.4 0.2 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Putative sensor DUF1929 PF09118.6 EXF85878.1 - 9.9e-24 83.2 0.0 2.1e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) PAN_1 PF00024.21 EXF85878.1 - 1.5e-15 56.6 8.9 3e-08 33.2 1.2 2.3 2 0 0 2 2 2 2 PAN domain Kelch_6 PF13964.1 EXF85878.1 - 2.7e-14 52.5 0.0 0.00028 20.9 0.0 4.1 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.20 EXF85878.1 - 2.6e-12 46.0 0.0 0.0013 18.2 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.1 EXF85878.1 - 9.8e-12 44.4 4.0 0.053 13.3 0.0 5.8 5 1 0 5 5 5 3 Galactose oxidase, central domain Kelch_2 PF07646.10 EXF85878.1 - 7.8e-10 38.1 0.0 0.0071 16.0 0.0 4.9 4 1 0 4 4 4 3 Kelch motif PAN_4 PF14295.1 EXF85878.1 - 1.1e-05 25.0 10.6 0.0061 16.2 1.1 2.8 2 0 0 2 2 2 2 PAN domain Glyoxal_oxid_N PF07250.6 EXF85878.1 - 1.3e-05 24.4 0.0 0.15 11.0 0.0 2.7 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_3 PF13415.1 EXF85878.1 - 2.2e-05 24.4 0.1 0.27 11.4 0.0 3.8 3 0 0 3 3 3 1 Galactose oxidase, central domain MANEC PF07502.9 EXF85878.1 - 0.001 19.0 7.4 0.14 12.2 0.5 2.4 2 0 0 2 2 2 2 MANEC domain PAN_2 PF08276.6 EXF85878.1 - 2.8 7.8 9.8 8 6.3 1.9 2.5 2 0 0 2 2 2 0 PAN-like domain Ras PF00071.17 EXF85879.1 - 6.5e-40 136.1 0.0 1.2e-37 128.7 0.0 2.1 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EXF85879.1 - 7.5e-18 65.1 0.0 1.1e-17 64.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EXF85879.1 - 3.9e-11 42.4 0.0 6.3e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EXF85879.1 - 0.00011 22.1 0.0 0.00019 21.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EXF85879.1 - 0.0051 16.0 0.0 0.0074 15.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EXF85879.1 - 0.016 14.3 0.0 0.023 13.8 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF2411 PF10304.4 EXF85879.1 - 0.066 12.7 0.3 0.13 11.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2411) Sec63 PF02889.11 EXF85880.1 - 1.3e-153 510.7 0.0 2.2e-98 329.3 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EXF85880.1 - 1.1e-52 177.9 0.3 7.2e-28 97.1 0.4 3.6 4 0 0 4 4 4 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EXF85880.1 - 8e-17 60.8 0.0 6.5e-07 29.1 0.0 3.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.10 EXF85880.1 - 5e-15 55.8 0.0 4.9e-06 26.5 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EXF85880.1 - 6.7e-08 32.7 0.0 0.021 14.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EXF85880.1 - 1.5e-05 24.6 0.3 0.096 12.4 0.0 3.5 3 0 0 3 3 3 2 Part of AAA domain SNF2_N PF00176.18 EXF85880.1 - 0.00015 20.7 0.1 0.16 10.7 0.0 2.3 2 0 0 2 2 2 2 SNF2 family N-terminal domain IstB_IS21 PF01695.12 EXF85880.1 - 0.019 14.3 0.3 11 5.4 0.0 3.7 4 0 0 4 4 4 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 EXF85880.1 - 0.055 12.9 0.0 3.7 6.9 0.0 2.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_10 PF12846.2 EXF85880.1 - 0.064 12.6 0.0 20 4.4 0.0 3.5 4 0 0 4 4 4 0 AAA-like domain BTB PF00651.26 EXF85880.1 - 0.11 12.5 0.1 1.5 8.7 0.0 2.5 2 0 0 2 2 2 0 BTB/POZ domain DUF1071 PF06378.6 EXF85880.1 - 0.18 10.9 0.0 0.39 9.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) Synaptobrevin PF00957.16 EXF85881.1 - 2.7e-14 52.5 0.6 4e-14 51.9 0.4 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EXF85881.1 - 3.4e-14 52.1 0.0 6.6e-14 51.2 0.0 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Imm43 PF15602.1 EXF85881.1 - 0.072 13.0 0.0 0.47 10.4 0.0 1.9 2 0 0 2 2 2 0 Immunity protein 43 Gb3_synth PF04572.7 EXF85881.1 - 0.11 12.1 0.0 1.1 8.9 0.0 2.2 3 0 0 3 3 3 0 Alpha 1,4-glycosyltransferase conserved region Occludin_ELL PF07303.8 EXF85882.1 - 0.027 15.1 4.5 0.027 15.1 3.1 4.9 2 1 3 5 5 5 0 Occludin homology domain CorA PF01544.13 EXF85882.1 - 8.8 5.2 9.4 2.6 7.0 4.2 1.8 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein RNA_pol_Rpb5_C PF01191.14 EXF85883.1 - 4e-34 116.0 0.5 6.6e-34 115.3 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EXF85883.1 - 6.8e-28 96.9 0.0 1.1e-27 96.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb5, N-terminal domain EnY2 PF10163.4 EXF85884.1 - 0.09 12.7 0.1 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Transcription factor e(y)2 AAA PF00004.24 EXF85885.1 - 1.2e-98 326.4 0.0 6e-48 162.3 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EXF85885.1 - 6.3e-20 70.9 0.4 2.6e-19 68.9 0.2 2.2 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_2 PF07724.9 EXF85885.1 - 7.1e-14 52.0 0.0 2.6e-07 30.7 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EXF85885.1 - 1.1e-13 50.8 0.0 6.9e-06 25.2 0.0 3.0 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EXF85885.1 - 3.5e-13 49.4 0.4 9.4e-07 28.6 0.1 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EXF85885.1 - 1.3e-12 47.7 0.0 1.5e-05 24.9 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EXF85885.1 - 4.7e-12 46.1 0.4 0.00069 19.7 0.1 4.1 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.1 EXF85885.1 - 1.7e-11 44.4 0.0 0.0004 20.4 0.0 3.7 2 2 1 3 3 3 2 AAA ATPase domain AAA_17 PF13207.1 EXF85885.1 - 2.9e-11 44.2 0.0 0.00024 21.9 0.0 3.1 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 EXF85885.1 - 3.1e-09 36.0 0.0 0.00093 18.0 0.0 2.6 2 0 0 2 2 2 2 TIP49 C-terminus AAA_25 PF13481.1 EXF85885.1 - 1.2e-08 34.5 5.1 0.013 14.9 0.0 4.6 2 2 2 4 4 4 3 AAA domain AAA_14 PF13173.1 EXF85885.1 - 1.8e-08 34.3 0.0 0.0012 18.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EXF85885.1 - 3.4e-08 33.1 0.1 0.0054 16.1 0.0 2.7 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_19 PF13245.1 EXF85885.1 - 4.7e-08 32.6 2.1 0.0085 15.8 0.0 3.1 3 0 0 3 3 2 2 Part of AAA domain Zeta_toxin PF06414.7 EXF85885.1 - 1.3e-07 30.9 0.1 0.0079 15.3 0.0 2.7 3 0 0 3 3 2 2 Zeta toxin Mg_chelatase PF01078.16 EXF85885.1 - 1.7e-07 30.5 0.2 0.0057 15.8 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI CDC48_2 PF02933.12 EXF85885.1 - 2.4e-07 30.3 0.0 6.6e-07 28.8 0.0 1.8 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 RNA_helicase PF00910.17 EXF85885.1 - 5.4e-07 29.7 0.0 0.029 14.5 0.0 2.9 3 0 0 3 3 2 2 RNA helicase KaiC PF06745.8 EXF85885.1 - 8.3e-07 28.3 0.7 0.23 10.5 0.0 3.5 2 1 1 3 3 3 2 KaiC AAA_18 PF13238.1 EXF85885.1 - 1.5e-06 28.4 0.0 0.087 13.1 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF815 PF05673.8 EXF85885.1 - 1.7e-06 27.1 0.0 0.0091 14.9 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF815) AAA_24 PF13479.1 EXF85885.1 - 2.2e-06 27.4 0.2 0.095 12.2 0.0 3.0 3 0 0 3 3 2 2 AAA domain ResIII PF04851.10 EXF85885.1 - 2.7e-06 27.3 0.0 0.0024 17.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_28 PF13521.1 EXF85885.1 - 3.2e-06 27.2 0.0 0.085 12.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.12 EXF85885.1 - 7.3e-06 25.0 0.1 0.043 12.6 0.0 2.3 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Arch_ATPase PF01637.13 EXF85885.1 - 8.3e-06 25.6 0.0 5.2 6.7 0.0 4.1 2 2 2 4 4 4 0 Archaeal ATPase Sigma54_activ_2 PF14532.1 EXF85885.1 - 1.1e-05 25.5 0.0 0.05 13.6 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Sigma54_activat PF00158.21 EXF85885.1 - 1.5e-05 24.5 0.0 0.17 11.3 0.0 3.4 2 2 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.7 EXF85885.1 - 1.6e-05 24.6 0.1 0.085 12.5 0.0 3.2 3 0 0 3 3 3 1 NACHT domain ABC_tran PF00005.22 EXF85885.1 - 2.4e-05 24.6 0.0 0.23 11.7 0.0 3.5 2 1 0 2 2 2 2 ABC transporter PhoH PF02562.11 EXF85885.1 - 0.00013 21.3 0.2 0.5 9.5 0.0 2.6 2 0 0 2 2 2 2 PhoH-like protein Vps4_C PF09336.5 EXF85885.1 - 0.00014 21.6 0.1 0.00068 19.4 0.0 2.1 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_3 PF07726.6 EXF85885.1 - 0.00017 21.2 0.0 0.59 9.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.13 EXF85885.1 - 0.00017 21.3 0.0 0.84 9.2 0.0 3.0 3 0 0 3 3 3 2 Bacterial dnaA protein AAA_30 PF13604.1 EXF85885.1 - 0.00018 21.1 0.0 0.49 9.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_11 PF13086.1 EXF85885.1 - 0.00048 19.7 0.0 0.78 9.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 EXF85885.1 - 0.0005 19.0 0.1 0.55 9.0 0.0 2.7 3 0 0 3 3 3 2 NB-ARC domain NTPase_1 PF03266.10 EXF85885.1 - 0.00087 19.0 0.2 0.64 9.6 0.0 3.8 3 0 0 3 3 3 1 NTPase DUF2075 PF09848.4 EXF85885.1 - 0.0016 17.5 0.0 1.5 7.7 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) Viral_helicase1 PF01443.13 EXF85885.1 - 0.0062 16.0 0.0 0.27 10.7 0.0 2.4 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase KAP_NTPase PF07693.9 EXF85885.1 - 0.01 14.8 0.4 1.4 7.8 0.0 3.4 2 2 1 4 4 4 0 KAP family P-loop domain IPT PF01745.11 EXF85885.1 - 0.011 14.9 0.0 1.5 7.9 0.0 2.3 2 0 0 2 2 2 0 Isopentenyl transferase UPF0079 PF02367.12 EXF85885.1 - 0.019 14.5 0.1 8.9 5.9 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 T2SE PF00437.15 EXF85885.1 - 0.031 13.1 0.0 1.3 7.8 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_10 PF12846.2 EXF85885.1 - 0.031 13.7 0.6 1.6 8.0 0.0 3.4 3 1 1 4 4 4 0 AAA-like domain Zot PF05707.7 EXF85885.1 - 0.063 12.7 0.2 16 4.8 0.1 3.7 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) AFG1_ATPase PF03969.11 EXF85885.1 - 0.08 11.7 0.0 9.7 4.8 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase AAA_23 PF13476.1 EXF85885.1 - 0.083 13.2 0.1 4.4 7.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 EXF85885.1 - 0.093 12.6 0.1 8.3 6.2 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase MobB PF03205.9 EXF85885.1 - 0.11 12.2 1.4 3.5 7.3 0.0 3.5 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.5 EXF85885.1 - 0.11 11.6 0.3 11 5.1 0.0 2.8 3 0 0 3 3 3 0 Chromatin associated protein KTI12 YjeF_N PF03853.10 EXF85887.1 - 9.2e-40 136.0 0.1 1.6e-39 135.1 0.1 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus FDF PF09532.5 EXF85887.1 - 6.6e-08 33.0 1.2 6.6e-08 33.0 0.8 1.9 2 0 0 2 2 2 1 FDF domain PIF1 PF05970.9 EXF85888.1 - 2.4e-59 201.1 0.2 2.6e-45 154.9 0.0 2.3 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.1 EXF85888.1 - 4e-17 62.4 0.0 7.5e-17 61.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EXF85888.1 - 2e-07 31.2 0.0 9.7e-07 28.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EXF85888.1 - 1.9e-06 27.5 0.1 5.6e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain UvrD_C_2 PF13538.1 EXF85888.1 - 5.2e-05 23.3 0.0 0.00052 20.1 0.0 2.5 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA PF00004.24 EXF85888.1 - 9e-05 22.6 0.0 0.00026 21.2 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EXF85888.1 - 0.00016 21.6 0.0 0.00046 20.2 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Herpes_Helicase PF02689.9 EXF85888.1 - 0.00051 17.9 0.0 0.0018 16.1 0.0 1.7 2 0 0 2 2 2 1 Helicase ABC_tran PF00005.22 EXF85888.1 - 0.0014 18.9 1.1 0.0081 16.4 0.0 2.5 1 1 1 2 2 2 1 ABC transporter PhoH PF02562.11 EXF85888.1 - 0.0018 17.5 0.0 0.004 16.3 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein AAA_5 PF07728.9 EXF85888.1 - 0.003 17.2 0.4 0.015 15.0 0.1 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EXF85888.1 - 0.013 15.6 0.0 0.04 14.0 0.0 1.8 1 0 0 1 1 1 0 RNA helicase T2SE PF00437.15 EXF85888.1 - 0.016 14.1 0.0 0.028 13.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_14 PF13173.1 EXF85888.1 - 0.024 14.5 0.0 0.094 12.6 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EXF85888.1 - 0.027 13.8 0.0 0.074 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EXF85888.1 - 0.03 13.9 0.0 0.063 12.9 0.0 1.5 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.4 EXF85888.1 - 0.032 13.2 0.0 0.072 12.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AFG1_ATPase PF03969.11 EXF85888.1 - 0.034 12.9 0.0 0.086 11.6 0.0 1.6 2 0 0 2 2 2 0 AFG1-like ATPase AAA_29 PF13555.1 EXF85888.1 - 0.036 13.6 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP-synt_ab PF00006.20 EXF85888.1 - 0.049 13.1 0.0 0.2 11.1 0.0 2.2 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain IstB_IS21 PF01695.12 EXF85888.1 - 0.058 12.8 0.4 0.7 9.2 0.0 2.5 3 0 0 3 3 3 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 EXF85888.1 - 0.089 12.4 0.0 0.28 10.8 0.0 1.9 1 1 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 EXF85888.1 - 0.09 12.1 0.0 0.26 10.6 0.0 1.8 2 0 0 2 2 1 0 AAA-like domain DUF258 PF03193.11 EXF85888.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_11 PF13086.1 EXF85888.1 - 0.49 9.9 0.0 0.49 9.9 0.0 2.7 3 0 0 3 3 3 0 AAA domain DCP1 PF06058.8 EXF85889.1 - 0.044 13.8 0.3 0.08 12.9 0.2 1.3 1 0 0 1 1 1 0 Dcp1-like decapping family Prenyltrans PF00432.16 EXF85890.1 - 1.2e-42 143.1 18.7 2.9e-11 42.7 0.3 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EXF85890.1 - 2.6e-22 79.3 0.0 1.7e-16 60.6 0.0 3.8 2 1 2 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EXF85890.1 - 0.0018 18.2 0.0 0.054 13.5 0.0 2.8 3 1 0 3 3 3 1 Prenyltransferase-like Zn_clus PF00172.13 EXF85891.1 - 0.0031 17.3 7.7 0.0067 16.3 5.4 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain BRAP2 PF07576.7 EXF85893.1 - 1.3e-20 72.9 0.0 2.3e-20 72.1 0.0 1.3 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EXF85893.1 - 6.9e-19 67.7 5.1 3e-18 65.7 3.7 1.9 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EXF85893.1 - 4e-10 39.3 10.2 4e-10 39.3 7.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EXF85893.1 - 6.9e-06 25.6 8.6 2e-05 24.1 5.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EXF85893.1 - 7.3e-06 25.6 8.8 7.3e-06 25.6 6.1 2.0 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EXF85893.1 - 5.9e-05 23.0 9.6 5.9e-05 23.0 6.6 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EXF85893.1 - 0.0001 21.8 7.7 0.0001 21.8 5.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EXF85893.1 - 0.0011 18.6 2.4 0.0011 18.6 1.6 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EXF85893.1 - 0.0046 17.0 6.0 0.0046 17.0 4.2 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EXF85893.1 - 0.0051 16.5 3.5 0.014 15.1 2.4 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EXF85893.1 - 0.047 13.5 7.4 0.12 12.1 5.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF4200 PF13863.1 EXF85893.1 - 0.079 12.9 17.7 0.21 11.5 2.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) zf-RING_4 PF14570.1 EXF85893.1 - 0.19 11.3 7.1 0.42 10.2 5.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_RING PF05883.6 EXF85893.1 - 0.21 11.3 0.8 0.59 9.9 0.6 1.7 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain FliD_N PF02465.13 EXF85893.1 - 0.67 10.3 10.7 0.32 11.3 0.4 2.4 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Prok-RING_4 PF14447.1 EXF85893.1 - 1.2 8.7 11.4 7.4 6.2 4.9 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 EXF85893.1 - 2.9 7.8 9.4 1.9 8.4 4.3 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF972 PF06156.8 EXF85893.1 - 4.8 7.5 14.9 1.1 9.5 2.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) ESCRT-II PF05871.7 EXF85894.1 - 6.6e-49 165.4 0.0 3.6e-48 163.0 0.0 1.9 1 1 0 1 1 1 1 ESCRT-II complex subunit PTCB-BRCT PF12738.2 EXF85895.1 - 2.5e-30 104.1 0.1 3.7e-21 74.7 0.2 4.6 4 0 0 4 4 4 4 twin BRCT domain BRCT PF00533.21 EXF85895.1 - 2.6e-29 101.2 0.1 6.6e-12 45.4 0.0 5.0 5 0 0 5 5 5 4 BRCA1 C Terminus (BRCT) domain GMC_oxred_N PF00732.14 EXF85896.1 - 5.5e-57 193.1 0.0 6.9e-57 192.8 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF85896.1 - 1.6e-34 119.2 0.0 3.3e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EXF85896.1 - 9.9e-06 24.6 4.8 0.00031 19.7 0.5 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF85896.1 - 1.2e-05 24.3 0.9 0.0016 17.3 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EXF85896.1 - 4.8e-05 23.3 0.1 0.00014 21.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EXF85896.1 - 0.00025 20.0 0.2 0.00046 19.2 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Thi4 PF01946.12 EXF85896.1 - 0.0018 17.4 0.9 0.023 13.7 0.2 2.2 2 0 0 2 2 2 1 Thi4 family HI0933_like PF03486.9 EXF85896.1 - 0.002 16.6 0.8 0.094 11.1 0.1 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.9 EXF85896.1 - 0.0031 17.3 0.0 0.13 12.1 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF85896.1 - 0.012 14.5 0.1 0.28 10.0 0.0 2.1 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.14 EXF85896.1 - 0.017 14.1 0.0 0.03 13.3 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.22 EXF85896.1 - 0.048 14.0 0.2 1.2 9.5 0.1 3.2 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF85896.1 - 0.27 11.0 1.2 1.4 8.6 0.1 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding p450 PF00067.17 EXF85897.1 - 3.9e-44 150.9 0.0 9.6e-44 149.6 0.0 1.6 1 1 0 1 1 1 1 Cytochrome P450 adh_short PF00106.20 EXF85898.1 - 1.8e-18 66.9 4.0 2.5e-18 66.5 2.8 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF85898.1 - 2.1e-07 30.7 1.0 3e-07 30.2 0.7 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF85898.1 - 2.5e-07 30.7 0.5 5e-07 29.7 0.4 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Shikimate_DH PF01488.15 EXF85898.1 - 0.0017 18.4 0.0 0.0029 17.7 0.0 1.3 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Polysacc_synt_2 PF02719.10 EXF85898.1 - 0.0018 17.2 0.0 0.0021 16.9 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EXF85898.1 - 0.0048 16.3 0.3 0.015 14.7 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EXF85898.1 - 0.031 14.0 0.8 0.073 12.8 0.6 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase UbiA PF01040.13 EXF85900.1 - 2.6e-13 49.7 3.6 3.5e-13 49.3 2.5 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family FAD_binding_4 PF01565.18 EXF85901.1 - 2.8e-20 72.2 3.4 5.6e-20 71.2 2.4 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF85901.1 - 6.1e-08 32.4 0.1 1.5e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like adh_short PF00106.20 EXF85902.1 - 0.035 14.0 0.0 0.2 11.5 0.0 2.1 2 0 0 2 2 2 0 short chain dehydrogenase Sec7 PF01369.15 EXF85903.1 - 1.1e-67 227.4 4.9 8.4e-67 224.5 0.5 3.2 3 0 0 3 3 3 1 Sec7 domain Sec7_N PF12783.2 EXF85903.1 - 7.9e-51 171.8 3.1 7.9e-51 171.8 2.1 2.9 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EXF85903.1 - 3.8e-32 109.6 4.2 3.5e-31 106.5 0.1 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) 2-oxoacid_dh PF00198.18 EXF85904.1 - 3.6e-74 248.9 0.0 4.7e-74 248.5 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EXF85904.1 - 1.7e-18 66.0 0.5 4.8e-18 64.5 0.3 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EXF85904.1 - 2.9e-10 39.5 1.1 5.3e-10 38.7 0.1 2.0 2 0 0 2 2 2 1 e3 binding domain Ribosomal_60s PF00428.14 EXF85904.1 - 0.54 10.6 6.7 0.34 11.3 2.4 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Fungal_trans PF04082.13 EXF85905.1 - 6.3e-14 51.4 0.2 1.1e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF85905.1 - 2.3e-08 33.7 11.3 2.3e-08 33.7 7.9 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NAD_binding_10 PF13460.1 EXF85906.1 - 5.5e-06 26.5 0.0 7.1e-06 26.1 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EXF85906.1 - 0.011 14.6 0.0 0.046 12.6 0.0 1.8 1 1 1 2 2 2 0 Male sterility protein DapB_N PF01113.15 EXF85906.1 - 0.06 13.2 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Methyltransf_23 PF13489.1 EXF85909.1 - 2.3e-20 72.9 0.0 5e-20 71.8 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF85909.1 - 9.4e-10 38.2 0.0 1.9e-09 37.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF85909.1 - 4.7e-07 30.3 0.0 2.7e-06 27.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF85909.1 - 6.8e-07 29.6 0.0 2.1e-06 28.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF85909.1 - 7.8e-07 29.4 0.0 1.5e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF85909.1 - 0.0014 18.9 0.0 0.0048 17.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.14 EXF85909.1 - 0.0036 16.8 0.0 0.022 14.2 0.0 2.0 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.12 EXF85909.1 - 0.006 15.6 0.0 0.018 14.0 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 EXF85909.1 - 0.048 12.7 0.0 0.96 8.5 0.0 2.6 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_17 PF12692.2 EXF85909.1 - 0.059 13.0 0.0 0.85 9.2 0.0 2.5 3 0 0 3 3 3 0 S-adenosyl-L-methionine methyltransferase Methyltransf_26 PF13659.1 EXF85909.1 - 0.068 13.2 0.0 0.35 10.8 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EXF85909.1 - 0.12 11.7 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain FtsJ PF01728.14 EXF85909.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase FAD_binding_3 PF01494.14 EXF85910.1 - 9.1e-12 44.6 0.2 3.4e-06 26.3 0.1 3.0 2 1 0 2 2 2 2 FAD binding domain DAO PF01266.19 EXF85910.1 - 1.4e-08 34.0 0.0 5.8e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF85910.1 - 2.4e-08 33.2 0.0 1.7e-05 23.8 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.9 EXF85910.1 - 2.9e-06 26.0 0.0 7.9e-06 24.5 0.0 1.6 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EXF85910.1 - 3.1e-05 23.9 0.0 8.5e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF85910.1 - 3.1e-05 23.9 0.0 9.3e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF85910.1 - 0.0017 18.4 0.0 0.003 17.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EXF85910.1 - 0.0037 15.9 0.0 0.0076 14.9 0.0 1.5 2 0 0 2 2 2 1 Tryptophan halogenase FAD_oxidored PF12831.2 EXF85910.1 - 0.008 15.2 0.2 0.026 13.5 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF85910.1 - 0.011 14.7 0.0 0.16 10.8 0.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein NAD_binding_9 PF13454.1 EXF85910.1 - 0.012 15.4 0.1 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EXF85910.1 - 0.012 15.8 0.0 0.031 14.5 0.0 1.8 2 1 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.22 EXF85910.1 - 0.033 14.5 0.0 0.1 13.0 0.0 1.8 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF85910.1 - 0.083 11.7 0.6 0.13 11.1 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A adh_short PF00106.20 EXF85911.1 - 9.4e-20 71.1 4.1 2.8e-18 66.3 2.8 2.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF85911.1 - 2.2e-11 43.9 0.0 7.6e-11 42.2 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF85911.1 - 3.9e-10 39.6 0.9 5.8e-10 39.1 0.1 1.7 2 0 0 2 2 2 1 KR domain Shikimate_DH PF01488.15 EXF85911.1 - 0.0029 17.7 0.2 0.0056 16.7 0.1 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase 3Beta_HSD PF01073.14 EXF85911.1 - 0.0075 15.0 0.0 0.012 14.3 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EXF85911.1 - 0.0099 15.8 0.1 0.03 14.3 0.1 1.7 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EXF85911.1 - 0.015 14.7 0.1 0.17 11.3 0.0 2.0 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EXF85911.1 - 0.025 13.5 0.1 0.036 13.0 0.1 1.2 1 0 0 1 1 1 0 Saccharopine dehydrogenase Polysacc_synt_2 PF02719.10 EXF85911.1 - 0.066 12.1 0.0 0.099 11.5 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Metallophos PF00149.23 EXF85913.1 - 0.00026 20.4 3.3 0.0019 17.6 2.3 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EXF85913.1 - 0.0027 17.5 0.2 0.0075 16.1 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Sugar_tr PF00083.19 EXF85914.1 - 1.2e-118 396.5 24.9 1.4e-118 396.3 17.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF85914.1 - 8e-18 64.2 48.3 1.1e-11 44.0 13.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2530 PF10745.4 EXF85914.1 - 0.1 12.5 3.7 0.32 10.9 0.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) Acetyltransf_1 PF00583.19 EXF85915.1 - 5.5e-11 42.3 0.1 9.6e-11 41.5 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EXF85915.1 - 8.7e-07 29.0 0.0 1.7e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EXF85915.1 - 2e-05 24.6 0.1 5.7e-05 23.2 0.0 1.8 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EXF85915.1 - 6.3e-05 22.7 0.0 0.00012 21.8 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EXF85915.1 - 0.00057 19.7 0.0 0.018 14.9 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EXF85915.1 - 0.0035 17.0 0.0 0.0075 15.9 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein DUF4232 PF14016.1 EXF85916.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4232) PPV_E2_N PF00508.12 EXF85916.1 - 0.15 11.2 0.1 0.18 10.9 0.1 1.1 1 0 0 1 1 1 0 E2 (early) protein, N terminal DUF2551 PF10826.3 EXF85917.1 - 0.039 13.8 0.0 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2551) Pec_lyase_C PF00544.14 EXF85919.1 - 3.1e-18 65.9 0.9 4.7e-18 65.3 0.7 1.3 1 0 0 1 1 1 1 Pectate lyase CBM_1 PF00734.13 EXF85919.1 - 6.9e-11 41.6 9.7 6.9e-11 41.6 6.7 2.3 2 0 0 2 2 2 1 Fungal cellulose binding domain MFS_1 PF07690.11 EXF85921.1 - 5.2e-22 78.0 37.0 2.1e-21 76.0 20.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2973 PF11189.3 EXF85921.1 - 0.039 13.7 0.0 0.12 12.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2973) 2-Hacid_dh_C PF02826.14 EXF85922.1 - 5.6e-42 142.8 0.0 1.2e-27 96.1 0.0 2.2 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.13 EXF85922.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Acetyltransf_1 PF00583.19 EXF85923.1 - 1.6e-12 47.2 0.1 2.5e-12 46.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EXF85923.1 - 3.2e-07 29.9 0.0 5.5e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EXF85923.1 - 1.4e-05 25.1 0.0 2.2e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EXF85923.1 - 0.00059 19.9 0.0 0.00095 19.2 0.0 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EXF85923.1 - 0.019 15.1 0.1 0.034 14.2 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EXF85923.1 - 0.038 13.9 0.0 0.12 12.2 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EXF85923.1 - 0.16 11.5 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Complex1_LYR PF05347.10 EXF85924.1 - 5.8e-08 32.4 1.5 1.3e-07 31.3 0.3 2.2 2 0 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EXF85924.1 - 3.7e-07 30.2 0.4 1.1e-06 28.7 0.3 1.8 1 0 0 1 1 1 1 Complex1_LYR-like Ank_4 PF13637.1 EXF85925.1 - 1.2e-14 54.3 1.3 1.3e-07 31.9 0.1 4.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EXF85925.1 - 3.8e-12 46.3 0.7 5.4e-06 26.6 0.5 3.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EXF85925.1 - 9.6e-11 40.9 1.2 0.0027 17.4 0.0 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EXF85925.1 - 3.3e-10 39.8 0.2 0.00089 19.4 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF85925.1 - 5.5e-10 38.5 0.3 0.0054 16.8 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat KilA-N PF04383.8 EXF85925.1 - 3.5e-05 23.3 0.2 0.00023 20.7 0.1 2.3 1 1 0 1 1 1 1 KilA-N domain Fez1 PF06818.10 EXF85925.1 - 0.046 13.7 8.2 0.099 12.6 5.7 1.5 1 0 0 1 1 1 0 Fez1 IncA PF04156.9 EXF85925.1 - 0.41 10.2 8.9 0.68 9.4 6.1 1.3 1 0 0 1 1 1 0 IncA protein FYVE PF01363.16 EXF85926.1 - 1.4e-24 85.7 20.1 2.5e-17 62.5 2.5 3.0 3 0 0 3 3 3 2 FYVE zinc finger zf-Di19 PF05605.7 EXF85926.1 - 0.00024 21.1 6.1 0.013 15.6 0.1 2.7 2 0 0 2 2 2 2 Drought induced 19 protein (Di19), zinc-binding zf-AN1 PF01428.11 EXF85926.1 - 0.00043 20.0 2.4 0.00043 20.0 1.7 3.7 3 1 1 4 4 4 1 AN1-like Zinc finger Rbsn PF11464.3 EXF85926.1 - 0.00049 19.6 0.9 0.00049 19.6 0.6 2.2 2 0 0 2 2 2 1 Rabenosyn Rab binding domain zf-C2H2_2 PF12756.2 EXF85926.1 - 0.01 15.9 1.5 1.1 9.4 0.0 2.9 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) UPF0547 PF10571.4 EXF85926.1 - 0.074 12.7 4.6 6.4 6.5 0.0 4.7 5 1 0 5 5 5 0 Uncharacterised protein family UPF0547 IBR PF01485.16 EXF85926.1 - 0.49 10.3 13.8 0.092 12.6 0.5 3.5 3 1 0 3 3 3 0 IBR domain HypA PF01155.14 EXF85926.1 - 8.2 6.1 13.6 1.3 8.7 0.6 3.7 3 1 1 4 4 4 0 Hydrogenase expression/synthesis hypA family NAD_binding_7 PF13241.1 EXF85927.1 - 7.7e-27 93.5 0.7 7.2e-22 77.5 0.0 2.3 1 1 1 2 2 2 2 Putative NAD(P)-binding Sirohm_synth_C PF14823.1 EXF85927.1 - 9.3e-24 82.5 0.1 1.4e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Sirohaem biosynthesis protein C-terminal Sirohm_synth_M PF14824.1 EXF85927.1 - 2.6e-15 55.1 0.1 4.2e-15 54.4 0.1 1.4 1 0 0 1 1 1 1 Sirohaem biosynthesis protein central CENP-L PF13092.1 EXF85928.1 - 2.1e-53 180.4 0.0 3.4e-53 179.7 0.0 1.3 1 0 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 Glyco_hydro_10 PF00331.15 EXF85929.1 - 3.6e-106 354.8 0.6 4.1e-106 354.6 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 10 Esterase_phd PF10503.4 EXF85930.1 - 6.3e-22 77.8 0.2 9.6e-22 77.3 0.1 1.2 1 0 0 1 1 1 1 Esterase PHB depolymerase Peptidase_S9 PF00326.16 EXF85930.1 - 5.8e-09 35.4 1.7 8.7e-09 34.9 1.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EXF85930.1 - 1.2e-06 28.3 0.1 1.6e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S10 PF00450.17 EXF85930.1 - 0.00015 21.1 0.5 0.0002 20.6 0.4 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.2 EXF85930.1 - 0.0012 18.7 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EXF85930.1 - 0.002 16.9 2.1 0.025 13.2 0.1 2.1 2 0 0 2 2 2 1 Carboxylesterase family Esterase PF00756.15 EXF85930.1 - 0.01 15.2 0.5 0.015 14.7 0.3 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.15 EXF85930.1 - 0.015 14.8 0.1 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold BAAT_C PF08840.6 EXF85930.1 - 0.031 13.9 0.2 0.051 13.2 0.1 1.3 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.8 EXF85930.1 - 0.062 12.8 0.0 0.086 12.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Fungal_trans PF04082.13 EXF85931.1 - 1.2e-25 89.9 0.2 1.7e-25 89.3 0.2 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF85931.1 - 1.3e-06 28.2 8.8 2.9e-06 27.0 6.1 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain GST_C PF00043.20 EXF85932.1 - 6.5e-08 32.4 0.0 1.1e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EXF85932.1 - 2.8e-07 30.3 0.0 1.4e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EXF85932.1 - 1.7e-06 28.3 0.1 2.7e-06 27.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EXF85932.1 - 0.00023 21.2 0.0 0.00068 19.8 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EXF85932.1 - 0.00098 19.0 0.0 0.0028 17.6 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain MFS_1 PF07690.11 EXF85933.1 - 2.3e-31 108.8 20.5 2.3e-31 108.8 14.2 1.4 2 0 0 2 2 2 1 Major Facilitator Superfamily DHDPS PF00701.17 EXF85934.1 - 6.1e-40 136.6 0.0 7.1e-40 136.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family p450 PF00067.17 EXF85935.1 - 8.8e-61 205.8 0.0 2.1e-60 204.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Pyr_redox PF00070.22 EXF85936.1 - 8.2e-15 54.9 1.7 4.9e-11 42.8 0.1 3.6 4 0 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EXF85936.1 - 2.2e-12 47.3 0.0 4.1e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF85936.1 - 2.6e-05 24.3 1.1 0.13 12.3 0.1 2.8 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF85936.1 - 0.00026 20.0 3.5 0.019 13.8 0.0 3.6 4 0 0 4 4 4 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.1 EXF85936.1 - 0.00041 20.1 0.7 0.18 11.5 0.0 3.7 4 0 0 4 4 4 1 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EXF85936.1 - 0.013 14.4 0.6 0.078 11.8 0.0 2.3 3 0 0 3 3 3 0 Lycopene cyclase protein ThiF PF00899.16 EXF85936.1 - 0.017 14.9 3.2 1.2 8.9 0.0 3.2 3 0 0 3 3 3 0 ThiF family Trp_halogenase PF04820.9 EXF85936.1 - 0.044 12.4 2.0 4.5 5.7 0.5 2.9 2 1 1 3 3 3 0 Tryptophan halogenase Thi4 PF01946.12 EXF85936.1 - 0.047 12.7 0.4 4 6.4 0.0 2.3 2 0 0 2 2 2 0 Thi4 family Malic_M PF03949.10 EXF85936.1 - 0.068 12.7 1.6 0.7 9.3 0.0 2.8 2 1 1 3 3 3 0 Malic enzyme, NAD binding domain TrkA_N PF02254.13 EXF85936.1 - 0.087 12.8 1.4 11 5.9 0.0 3.2 3 1 0 3 3 3 0 TrkA-N domain MFS_1 PF07690.11 EXF85938.1 - 6.8e-41 140.1 14.8 6.8e-41 140.1 10.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF85938.1 - 3.2e-12 45.7 14.0 9.3e-12 44.2 9.7 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.15 EXF85938.1 - 0.0015 16.6 1.1 0.56 8.2 0.1 2.4 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Peptidase_S48 PF03574.10 EXF85938.1 - 0.18 11.7 0.0 0.31 11.0 0.0 1.3 1 0 0 1 1 1 0 Peptidase family S48 DUF1049 PF06305.6 EXF85938.1 - 0.79 9.2 7.5 1.4 8.4 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) Gly_kinase PF02595.10 EXF85939.1 - 9.4e-97 324.0 9.2 1.1e-96 323.8 6.4 1.0 1 0 0 1 1 1 1 Glycerate kinase family 5_nucleotid_C PF02872.13 EXF85940.1 - 4.6e-41 140.3 0.0 1.1e-40 139.2 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain ABC_tran PF00005.22 EXF85940.1 - 3.8e-38 130.8 0.0 1.2e-27 96.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EXF85940.1 - 2.1e-22 79.8 14.8 3e-22 79.3 10.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EXF85940.1 - 2.1e-07 31.2 0.0 0.018 15.0 0.0 3.5 2 1 0 3 3 3 2 AAA domain Metallophos PF00149.23 EXF85940.1 - 1.9e-06 27.3 0.4 3.2e-06 26.6 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SMC_N PF02463.14 EXF85940.1 - 2.5e-06 26.9 0.3 0.1 11.8 0.0 3.3 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.1 EXF85940.1 - 0.0019 18.0 0.0 0.42 10.5 0.0 3.0 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 EXF85940.1 - 0.002 17.6 0.1 0.0042 16.5 0.0 1.5 1 0 0 1 1 1 1 FtsK/SpoIIIE family AAA_22 PF13401.1 EXF85940.1 - 0.0022 18.1 0.0 0.018 15.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain Metallophos_2 PF12850.2 EXF85940.1 - 0.0035 17.1 0.1 0.0089 15.8 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Mg_chelatase PF01078.16 EXF85940.1 - 0.0053 15.9 0.0 0.01 15.0 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI NTPase_1 PF03266.10 EXF85940.1 - 0.0098 15.6 0.1 0.051 13.2 0.0 2.2 2 0 0 2 2 2 1 NTPase AAA_10 PF12846.2 EXF85940.1 - 0.011 15.1 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain DUF87 PF01935.12 EXF85940.1 - 0.022 14.5 1.1 0.047 13.4 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function DUF87 AAA_25 PF13481.1 EXF85940.1 - 0.034 13.5 2.3 0.069 12.5 0.6 2.3 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EXF85940.1 - 0.036 13.6 0.3 0.11 12.1 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 EXF85940.1 - 0.039 14.4 0.0 0.087 13.3 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein DUF258 PF03193.11 EXF85940.1 - 0.093 11.9 0.2 0.21 10.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Pox_A32 PF04665.7 EXF85940.1 - 0.16 11.2 0.1 0.3 10.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein DUF3584 PF12128.3 EXF85940.1 - 0.53 7.5 0.1 0.77 7.0 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Methyltransf_23 PF13489.1 EXF85942.1 - 6.9e-23 81.1 0.0 1.1e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF85942.1 - 5.9e-09 36.5 0.0 5.6e-08 33.3 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF85942.1 - 1e-08 35.5 0.0 5.2e-08 33.2 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF85942.1 - 1.6e-07 31.6 0.0 3e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF85942.1 - 1.7e-07 30.9 0.0 4.9e-07 29.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF85942.1 - 3.7e-06 27.2 0.0 1e-05 25.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EXF85942.1 - 0.024 14.6 0.0 0.036 14.0 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 EXF85942.1 - 0.024 13.9 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 EXF85942.1 - 0.025 14.5 0.0 0.24 11.4 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_17 PF12692.2 EXF85942.1 - 0.026 14.1 0.0 1 9.0 0.0 2.2 2 0 0 2 2 2 0 S-adenosyl-L-methionine methyltransferase Methyltransf_4 PF02390.12 EXF85942.1 - 0.027 13.5 0.0 0.027 13.5 0.0 2.1 3 0 0 3 3 2 0 Putative methyltransferase Methyltransf_2 PF00891.13 EXF85942.1 - 0.033 13.3 0.0 0.059 12.5 0.0 1.5 1 0 0 1 1 1 0 O-methyltransferase Methyltransf_23 PF13489.1 EXF85943.1 - 7.4e-22 77.7 0.0 1.2e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF85943.1 - 1.5e-10 40.8 0.0 1.5e-09 37.6 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF85943.1 - 1.9e-09 38.0 0.0 2.5e-08 34.4 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF85943.1 - 2.8e-07 30.9 0.0 2.2e-06 28.0 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF85943.1 - 1.7e-06 28.3 0.0 3.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF85943.1 - 2.5e-05 24.5 0.0 6.6e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF85943.1 - 0.0003 19.9 0.1 0.0014 17.7 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase CMAS PF02353.15 EXF85943.1 - 0.0034 16.4 0.0 0.008 15.2 0.0 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EXF85943.1 - 0.0036 16.4 0.0 2.2 7.3 0.0 2.8 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EXF85943.1 - 0.023 14.7 0.0 0.063 13.3 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EXF85943.1 - 0.023 13.8 0.0 0.038 13.0 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EXF85943.1 - 0.034 14.1 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 EXF85943.1 - 0.089 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.1 EXF85944.1 - 9.3e-23 80.7 0.0 1.4e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF85944.1 - 8.2e-10 39.2 0.0 1e-08 35.6 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF85944.1 - 2.1e-08 33.9 0.0 2.2e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF85944.1 - 4.7e-07 30.2 0.0 8.1e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF85944.1 - 2e-06 28.1 0.0 1e-05 25.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF85944.1 - 0.00045 20.5 0.0 0.0014 18.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EXF85944.1 - 0.017 14.1 0.0 0.041 12.9 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_26 PF13659.1 EXF85944.1 - 0.048 13.7 0.0 0.21 11.5 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EXF85944.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NAD_binding_10 PF13460.1 EXF85945.1 - 5.5e-25 88.4 0.5 8.1e-25 87.8 0.4 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF85945.1 - 1.2e-05 24.8 0.0 3.1e-05 23.5 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EXF85945.1 - 0.032 13.4 0.0 2 7.5 0.0 2.2 2 0 0 2 2 2 0 NmrA-like family RmlD_sub_bind PF04321.12 EXF85945.1 - 0.035 12.9 0.0 0.061 12.2 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Lipase_GDSL_2 PF13472.1 EXF85945.1 - 0.073 13.1 0.1 0.12 12.5 0.1 1.4 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family peroxidase PF00141.18 EXF85946.1 - 8.9e-21 74.4 0.4 1.5e-20 73.7 0.3 1.2 1 0 0 1 1 1 1 Peroxidase Pyr_redox_3 PF13738.1 EXF85947.1 - 8.4e-22 78.2 0.0 1.4e-21 77.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EXF85947.1 - 2.2e-17 62.4 0.2 8.2e-16 57.2 0.0 2.3 2 1 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EXF85947.1 - 2.6e-08 33.7 0.0 8.2e-08 32.1 0.0 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EXF85947.1 - 3.9e-07 29.3 0.0 5.3e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EXF85947.1 - 3.2e-05 23.7 0.3 0.00072 19.3 0.0 3.0 3 1 0 3 3 3 1 FAD-NAD(P)-binding DAO PF01266.19 EXF85947.1 - 7.9e-05 21.7 0.2 0.055 12.3 0.1 3.2 2 1 1 3 3 3 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF85947.1 - 9.3e-05 22.3 0.0 0.0001 22.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF85947.1 - 0.00044 19.4 0.0 0.0033 16.5 0.0 2.1 2 0 0 2 2 2 1 Thi4 family DnaB_2 PF07261.6 EXF85947.1 - 0.017 14.7 0.0 0.73 9.4 0.0 2.4 2 0 0 2 2 2 0 Replication initiation and membrane attachment Bac_luciferase PF00296.15 EXF85948.1 - 6.3e-56 189.7 2.4 1e-55 189.0 1.7 1.2 1 0 0 1 1 1 1 Luciferase-like monooxygenase MFS_1 PF07690.11 EXF85949.1 - 3.9e-20 71.8 20.1 5.8e-20 71.3 13.9 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.2 EXF85949.1 - 0.013 15.2 0.7 0.013 15.2 0.5 2.3 2 0 0 2 2 2 0 MFS_1 like family Glyoxalase_2 PF12681.2 EXF85950.1 - 1.2e-10 41.9 0.0 1.5e-10 41.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EXF85950.1 - 3.3e-09 36.8 0.0 5.4e-09 36.1 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EXF85950.1 - 0.00064 19.6 0.0 0.00083 19.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily AA_permease PF00324.16 EXF85952.1 - 2.5e-122 408.6 45.3 2.8e-122 408.4 31.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF85952.1 - 2.8e-27 95.3 51.1 4e-27 94.8 35.4 1.1 1 0 0 1 1 1 1 Amino acid permease SAD_SRA PF02182.12 EXF85954.1 - 3e-28 98.0 0.0 4.1e-28 97.6 0.0 1.1 1 0 0 1 1 1 1 SAD/SRA domain Zn_clus PF00172.13 EXF85955.1 - 4.9e-07 29.5 9.0 4.9e-07 29.5 6.2 1.7 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain NmrA PF05368.8 EXF85956.1 - 7e-35 120.3 0.0 8.9e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF85956.1 - 3.3e-19 69.5 0.0 4.2e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF85956.1 - 0.00015 21.2 0.1 0.0007 19.0 0.1 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EXF85956.1 - 0.0013 18.6 1.7 0.0028 17.5 0.5 1.9 1 1 1 2 2 2 1 short chain dehydrogenase 3Beta_HSD PF01073.14 EXF85956.1 - 0.0029 16.3 0.0 0.0075 14.9 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EXF85956.1 - 0.016 14.1 0.1 0.81 8.5 0.0 2.3 1 1 0 2 2 2 0 Male sterility protein GFA PF04828.9 EXF85957.1 - 2.8e-09 36.8 6.8 1.6e-08 34.3 0.5 3.1 3 0 0 3 3 3 2 Glutathione-dependent formaldehyde-activating enzyme MFS_1 PF07690.11 EXF85958.1 - 8.6e-53 179.2 23.4 8.6e-53 179.2 16.2 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF85958.1 - 1.5e-11 43.5 9.9 1.5e-11 43.5 6.9 3.0 3 0 0 3 3 3 1 Sugar (and other) transporter TRI12 PF06609.8 EXF85958.1 - 9.9e-08 30.6 4.9 1.8e-07 29.7 3.4 1.3 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 EXF85958.1 - 0.00015 20.5 5.9 0.00023 20.0 1.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF791) MFS_3 PF05977.8 EXF85958.1 - 0.00041 18.5 5.3 0.00041 18.5 3.6 2.0 2 0 0 2 2 2 1 Transmembrane secretion effector DUF3353 PF11833.3 EXF85958.1 - 6.5 6.1 7.3 18 4.6 5.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3353) V-SNARE_C PF12352.3 EXF85959.1 - 2.1e-14 53.3 0.3 2.1e-14 53.3 0.2 2.6 3 0 0 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EXF85959.1 - 6.5e-05 22.5 0.1 0.001 18.7 0.0 2.5 2 1 1 3 3 3 1 Sec20 Sigma70_r4 PF04545.11 EXF85959.1 - 0.012 14.9 0.0 0.028 13.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 Spc7 PF08317.6 EXF85959.1 - 0.022 13.4 1.8 0.037 12.6 1.3 1.3 1 0 0 1 1 1 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.6 EXF85959.1 - 0.067 13.5 0.6 0.22 11.9 0.1 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal TPR_MLP1_2 PF07926.7 EXF85959.1 - 0.36 10.5 5.1 1.4 8.6 2.6 2.6 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein TPK_catalytic PF04263.11 EXF85960.1 - 8.8e-24 83.4 0.0 1.2e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EXF85960.1 - 3e-23 81.3 0.6 6.2e-23 80.3 0.4 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain CHCH PF06747.8 EXF85961.1 - 7.4e-06 25.7 5.0 1.2e-05 25.0 3.4 1.4 1 0 0 1 1 1 1 CHCH domain DUF3353 PF11833.3 EXF85962.1 - 0.19 11.1 3.0 1.3 8.4 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3353) Transport_MerF PF11431.3 EXF85962.1 - 5.1 6.8 8.4 0.36 10.4 0.7 2.2 2 0 0 2 2 2 0 Membrane transport protein MerF Myb_DNA-bind_3 PF12776.2 EXF85963.1 - 1.1e-20 74.0 0.2 1.1e-20 74.0 0.1 2.2 2 0 0 2 2 1 1 Myb/SANT-like DNA-binding domain PAT1 PF09770.4 EXF85963.1 - 0.00051 18.4 41.0 0.00061 18.1 28.4 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EXF85963.1 - 0.11 12.4 30.6 0.19 11.6 21.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-DHHC PF01529.15 EXF85963.1 - 0.12 11.7 0.7 0.15 11.4 0.5 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase SRP-alpha_N PF04086.8 EXF85963.1 - 0.16 11.3 11.2 0.3 10.4 7.7 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Suf PF05843.9 EXF85963.1 - 0.2 11.3 15.7 0.31 10.7 10.9 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4557 PF15101.1 EXF85963.1 - 0.83 9.4 20.3 1.8 8.3 14.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FimP PF09766.4 EXF85963.1 - 1 8.3 18.5 1.6 7.7 12.8 1.2 1 0 0 1 1 1 0 Fms-interacting protein Med15 PF09606.5 EXF85963.1 - 1.3 7.1 56.9 1.7 6.7 39.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Macoilin PF09726.4 EXF85963.1 - 1.5 7.0 12.4 2 6.6 8.6 1.1 1 0 0 1 1 1 0 Transmembrane protein OmpH PF03938.9 EXF85963.1 - 9 6.2 28.0 16 5.4 19.4 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Band_3_cyto PF07565.8 EXF85963.1 - 9.5 5.6 10.6 16 4.8 7.4 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Melittin PF01372.12 EXF85964.1 - 0.25 10.7 1.1 2.5 7.5 0.1 2.2 2 0 0 2 2 2 0 Melittin Asp PF00026.18 EXF85965.1 - 1e-63 215.5 9.2 1.2e-63 215.2 6.3 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease Asp_protease_2 PF13650.1 EXF85965.1 - 1.9e-05 25.0 1.9 0.018 15.5 0.5 2.8 2 1 0 2 2 2 2 Aspartyl protease TAXi_N PF14543.1 EXF85965.1 - 0.002 18.0 0.0 0.012 15.6 0.0 2.2 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Aminotran_5 PF00266.14 EXF85966.1 - 2.4e-18 66.0 0.0 2.1e-17 62.9 0.0 2.0 1 1 0 1 1 1 1 Aminotransferase class-V ACC_central PF08326.7 EXF85967.1 - 4.5e-254 844.8 0.0 5.7e-254 844.5 0.0 1.1 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EXF85967.1 - 8.7e-174 578.4 0.0 1.2e-173 578.0 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EXF85967.1 - 8.2e-51 172.2 0.0 1.5e-50 171.3 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EXF85967.1 - 3.3e-24 85.1 0.1 6.9e-24 84.0 0.1 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EXF85967.1 - 5e-21 74.7 0.0 1.1e-19 70.3 0.0 2.9 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EXF85967.1 - 2.4e-16 59.1 0.1 5e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EXF85967.1 - 2.1e-08 34.1 0.0 5.9e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EXF85967.1 - 7.1e-07 28.2 0.0 0.01 14.6 0.0 2.9 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon Biotin_lipoyl_2 PF13533.1 EXF85967.1 - 0.0061 16.2 0.0 0.016 14.8 0.0 1.7 1 0 0 1 1 1 1 Biotin-lipoyl like Dala_Dala_lig_C PF07478.8 EXF85967.1 - 0.016 14.6 0.0 0.047 13.0 0.0 1.8 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus RnfC_N PF13375.1 EXF85967.1 - 0.025 14.3 0.0 0.09 12.4 0.0 1.9 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain DUF1936 PF09151.5 EXF85968.1 - 0.024 14.1 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1936) Cwf_Cwc_15 PF04889.7 EXF85968.1 - 0.037 13.7 1.4 0.054 13.1 1.0 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Abhydrolase_6 PF12697.2 EXF85969.1 - 4.7e-26 92.0 1.3 9.7e-26 91.0 0.9 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF85969.1 - 4.5e-12 45.9 0.0 8.6e-11 41.7 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF85969.1 - 9.9e-10 38.3 0.0 5.3e-09 35.9 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.3 EXF85969.1 - 2.1e-05 24.2 0.0 4.3e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase PF07224.6 EXF85969.1 - 0.031 13.0 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Esterase PF00756.15 EXF85969.1 - 0.087 12.2 0.1 1.1 8.6 0.0 2.2 2 0 0 2 2 2 0 Putative esterase Chlorophyllase2 PF12740.2 EXF85969.1 - 0.13 11.0 0.0 0.28 10.0 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase enzyme Glyco_hydro_43 PF04616.9 EXF85970.1 - 6.8e-74 248.5 0.6 1.1e-73 247.8 0.1 1.5 2 0 0 2 2 2 1 Glycosyl hydrolases family 43 DUF1349 PF07081.6 EXF85970.1 - 0.0061 15.9 0.1 0.0098 15.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1349) Fungal_trans PF04082.13 EXF85971.1 - 1.3e-08 34.0 1.1 1.3e-08 34.0 0.8 2.0 2 1 0 2 2 2 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF85971.1 - 0.00054 19.8 1.7 0.0011 18.8 1.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Sugar_tr PF00083.19 EXF85972.1 - 1.5e-66 224.8 18.9 1.7e-66 224.6 13.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF85972.1 - 5.3e-10 38.5 33.4 2.3e-05 23.2 9.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MttA_Hcf106 PF02416.11 EXF85972.1 - 0.23 10.5 4.4 2.2 7.4 0.1 3.6 4 0 0 4 4 4 0 mttA/Hcf106 family PI-PLC-X PF00388.14 EXF85973.1 - 7.4e-61 203.8 0.0 1.2e-60 203.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EXF85973.1 - 2.1e-38 130.9 0.0 3.3e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain FMO-like PF00743.14 EXF85974.1 - 1.6e-25 89.3 0.0 5.9e-12 44.5 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EXF85974.1 - 1.4e-16 61.1 0.0 4e-15 56.4 0.0 2.8 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF85974.1 - 8.8e-08 31.4 0.2 0.0003 19.8 0.0 3.0 3 1 1 4 4 4 3 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EXF85974.1 - 2.3e-07 30.6 1.1 0.00049 19.9 0.0 3.1 3 0 0 3 3 3 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EXF85974.1 - 1.6e-05 24.8 0.0 0.0022 17.9 0.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF85974.1 - 0.00023 21.0 0.0 0.00059 19.8 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF85974.1 - 0.089 11.6 0.1 0.93 8.3 0.0 2.7 3 1 1 4 4 4 0 FAD dependent oxidoreductase Thi4 PF01946.12 EXF85974.1 - 0.17 10.9 0.0 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 Thi4 family HI0933_like PF03486.9 EXF85974.1 - 0.27 9.6 0.0 0.47 8.8 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein GOLGA2L5 PF15070.1 EXF85975.1 - 0.077 11.4 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 NmrA PF05368.8 EXF85976.1 - 8.7e-18 64.4 0.2 1.2e-17 63.9 0.1 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF85976.1 - 2.6e-15 56.9 0.0 3.8e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF85976.1 - 3.5e-09 36.4 1.0 1.5e-07 31.0 0.7 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EXF85976.1 - 0.0002 21.3 1.2 0.00057 19.8 0.8 1.7 1 1 0 1 1 1 1 short chain dehydrogenase Shikimate_DH PF01488.15 EXF85976.1 - 0.00092 19.3 0.0 0.03 14.4 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase KR PF08659.5 EXF85976.1 - 0.0037 16.9 0.6 0.0086 15.7 0.4 1.6 1 1 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EXF85976.1 - 0.0079 15.2 0.2 0.012 14.6 0.2 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 EXF85976.1 - 0.024 15.0 2.5 0.17 12.2 0.7 2.7 2 1 1 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent RmlD_sub_bind PF04321.12 EXF85976.1 - 0.044 12.6 0.5 0.086 11.7 0.1 1.7 2 0 0 2 2 2 0 RmlD substrate binding domain Semialdhyde_dh PF01118.19 EXF85976.1 - 0.078 13.2 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Barttin PF15462.1 EXF85977.1 - 0.04 13.5 0.3 0.073 12.7 0.2 1.3 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) GLTSCR1 PF15249.1 EXF85977.1 - 0.073 13.1 0.1 2.2 8.4 0.0 3.1 3 0 0 3 3 3 0 Glioma tumor suppressor candidate region FAD_binding_4 PF01565.18 EXF85978.1 - 2.3e-20 72.4 0.7 4.9e-20 71.4 0.5 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF85978.1 - 0.0017 18.2 0.3 0.0099 15.7 0.1 2.2 2 0 0 2 2 2 1 Berberine and berberine like LysM PF01476.15 EXF85980.1 - 5.2e-07 29.4 0.0 6.4e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 LysM domain adh_short PF00106.20 EXF85981.1 - 1.9e-28 99.4 0.3 2.6e-28 99.0 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF85981.1 - 3.5e-23 82.6 0.0 4.4e-23 82.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF85981.1 - 3.5e-15 56.1 0.1 4.9e-15 55.6 0.1 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EXF85981.1 - 7.8e-06 26.0 0.2 1e-05 25.6 0.2 1.3 1 0 0 1 1 1 1 NADH(P)-binding THF_DHG_CYH_C PF02882.14 EXF85981.1 - 0.022 13.8 0.1 0.041 12.9 0.1 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain NAD_binding_2 PF03446.10 EXF85981.1 - 0.026 14.3 0.2 0.049 13.4 0.1 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ADH_zinc_N PF00107.21 EXF85981.1 - 0.033 13.7 0.4 8.5 5.9 0.0 2.4 1 1 0 2 2 2 0 Zinc-binding dehydrogenase DUF1372 PF07116.6 EXF85981.1 - 0.07 13.0 0.1 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1372) Shisa PF13908.1 EXF85982.1 - 0.0039 17.3 0.6 0.0039 17.3 0.4 2.5 1 1 1 2 2 2 2 Wnt and FGF inhibitory regulator NfeD PF01957.13 EXF85983.1 - 0.0085 16.2 0.1 0.011 15.9 0.1 1.1 1 0 0 1 1 1 1 NfeD-like C-terminal, partner-binding Bax1-I PF01027.15 EXF85983.1 - 0.039 13.5 0.4 0.051 13.1 0.3 1.1 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Transgly_assoc PF04226.8 EXF85983.1 - 3 7.9 7.4 5.9 7.0 0.6 2.4 2 0 0 2 2 2 0 Transglycosylase associated protein HELP PF03451.9 EXF85984.1 - 0.037 13.5 0.0 0.088 12.3 0.0 1.6 1 0 0 1 1 1 0 HELP motif HlyD PF00529.15 EXF85984.1 - 0.045 13.0 0.2 0.067 12.4 0.1 1.3 1 0 0 1 1 1 0 HlyD family secretion protein DASH_Dad4 PF08650.5 EXF85985.1 - 0.28 11.1 2.6 0.68 9.8 0.0 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad4 DUF1180 PF06679.7 EXF85985.1 - 0.64 9.8 12.2 0.1 12.4 3.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Catalase PF00199.14 EXF85986.1 - 7.5e-161 535.0 0.6 1e-160 534.6 0.4 1.2 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EXF85986.1 - 9.7e-21 73.4 0.0 2.2e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive DJ-1_PfpI PF01965.19 EXF85986.1 - 3.9e-10 39.3 0.0 7.8e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 DJ-1/PfpI family DUF814 PF05670.8 EXF85988.1 - 3.2e-11 42.9 0.1 0.0001 22.0 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF814) HeLo PF14479.1 EXF85989.1 - 1.5e-05 24.8 4.7 0.0044 16.7 0.1 3.0 2 1 1 3 3 3 2 Prion-inhibition and propagation Tup_N PF08581.5 EXF85990.1 - 0.1 12.8 0.2 0.56 10.4 0.2 2.4 1 0 0 1 1 1 0 Tup N-terminal RINGv PF12906.2 EXF85991.1 - 1.1e-16 60.5 9.3 1.8e-16 59.9 6.5 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EXF85991.1 - 0.016 14.9 8.2 0.029 14.2 5.7 1.4 1 0 0 1 1 1 0 Ring finger domain Shisa PF13908.1 EXF85991.1 - 2.8 8.0 0.0 2.8 8.0 0.0 2.9 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator zf-RING_4 PF14570.1 EXF85991.1 - 3.1 7.4 7.4 5.5 6.6 5.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.3 EXF85991.1 - 3.4 7.7 5.3 6.3 6.8 3.7 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain GCIP PF13324.1 EXF85991.1 - 4.1 6.5 4.7 7.3 5.7 3.2 1.3 1 0 0 1 1 1 0 Grap2 and cyclin-D-interacting DUF2921 PF11145.3 EXF85992.1 - 0.013 13.2 0.0 0.016 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2921) tRNA-synt_1d PF00750.14 EXF85993.1 - 5.8e-81 272.0 2.8 8.7e-81 271.4 2.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EXF85993.1 - 3.9e-29 101.0 0.3 7.7e-29 100.0 0.2 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain FAD_binding_8 PF08022.7 EXF85993.1 - 1.5e-12 47.2 0.0 3.8e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EXF85993.1 - 7.4e-12 45.4 18.6 8.4e-12 45.2 10.9 2.4 2 0 0 2 2 2 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.7 EXF85993.1 - 2.9e-10 40.2 0.0 7.3e-10 38.9 0.0 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Arg_tRNA_synt_N PF03485.11 EXF85993.1 - 0.1 13.1 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain p450 PF00067.17 EXF85994.1 - 8.1e-54 182.8 0.0 1.6e-53 181.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EXF85995.1 - 3.8e-55 187.2 0.0 4.3e-55 187.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Fungal_trans PF04082.13 EXF85996.1 - 8.5e-27 93.6 0.1 1.8e-26 92.6 0.1 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain adh_short PF00106.20 EXF85997.1 - 4.2e-24 85.3 0.6 3.8e-23 82.2 0.4 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF85997.1 - 3.1e-16 59.8 0.0 1.7e-15 57.4 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF85997.1 - 3.5e-11 43.0 0.2 4.8e-09 36.1 0.0 2.2 2 0 0 2 2 2 2 KR domain Epimerase PF01370.16 EXF85997.1 - 0.031 13.7 0.0 2.5 7.4 0.0 2.2 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family HMG_box_2 PF09011.5 EXF85998.1 - 0.023 15.0 6.6 0.033 14.5 1.2 2.3 2 0 0 2 2 2 0 HMG-box domain DUF3106 PF11304.3 EXF85998.1 - 0.044 14.1 4.7 0.92 9.9 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3106) HMG_box PF00505.14 EXF85998.1 - 0.052 13.8 6.5 0.74 10.1 1.2 2.3 2 0 0 2 2 2 0 HMG (high mobility group) box TipAS PF07739.8 EXF85998.1 - 1.6 9.0 5.4 0.74 10.1 1.3 1.9 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain AA_permease PF00324.16 EXF85999.1 - 1.6e-117 392.8 36.5 2.1e-117 392.4 25.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF85999.1 - 4.6e-23 81.4 39.8 6.7e-23 80.9 27.6 1.1 1 0 0 1 1 1 1 Amino acid permease adh_short PF00106.20 EXF86000.1 - 5.3e-16 58.9 0.2 2.4e-14 53.6 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EXF86000.1 - 0.00019 21.1 0.1 0.00035 20.2 0.0 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF86000.1 - 0.00086 19.1 0.2 0.0033 17.2 0.0 2.0 2 1 1 3 3 3 1 Enoyl-(Acyl carrier protein) reductase MHC2-interact PF09307.5 EXF86001.1 - 0.034 13.9 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 CLIP, MHC2 interacting Amidase PF01425.16 EXF86002.1 - 9.3e-65 219.1 0.2 3e-63 214.2 0.0 2.1 2 0 0 2 2 2 2 Amidase GMC_oxred_N PF00732.14 EXF86003.1 - 3.2e-51 174.2 0.0 4.9e-51 173.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF86003.1 - 1.2e-29 103.4 0.0 2.4e-29 102.5 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase ABC_tran PF00005.22 EXF86003.1 - 1.2e-26 93.5 0.0 5.8e-26 91.4 0.0 2.0 2 0 0 2 2 2 1 ABC transporter ABC2_membrane PF01061.19 EXF86003.1 - 1.1e-14 54.1 6.8 1.8e-14 53.3 4.7 1.4 1 0 0 1 1 1 1 ABC-2 type transporter DAO PF01266.19 EXF86003.1 - 1e-06 27.9 0.0 1.1e-05 24.5 0.0 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF86003.1 - 7.6e-05 21.7 0.0 0.063 12.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain AAA_21 PF13304.1 EXF86003.1 - 0.00031 20.8 0.0 0.01 15.7 0.0 2.3 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EXF86003.1 - 0.00046 19.4 0.4 0.001 18.2 0.3 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Lycopene_cycl PF05834.7 EXF86003.1 - 0.0015 17.5 0.0 0.0023 16.9 0.0 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.1 EXF86003.1 - 0.0016 18.4 0.0 0.0038 17.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AAA_25 PF13481.1 EXF86003.1 - 0.0018 17.6 0.1 0.054 12.8 0.1 2.3 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 EXF86003.1 - 0.0032 16.5 12.9 0.0058 15.7 9.0 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein Thi4 PF01946.12 EXF86003.1 - 0.0068 15.5 0.0 0.012 14.6 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EXF86003.1 - 0.0069 16.2 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF86003.1 - 0.0089 15.8 0.1 0.23 11.2 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding ArgK PF03308.11 EXF86003.1 - 0.011 14.5 1.3 0.02 13.6 0.3 1.7 2 0 0 2 2 2 0 ArgK protein AAA_29 PF13555.1 EXF86003.1 - 0.013 15.0 1.6 0.04 13.4 1.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.18 EXF86003.1 - 0.02 14.7 0.3 0.35 10.6 0.0 2.3 2 0 0 2 2 2 0 Dynamin family AAA_10 PF12846.2 EXF86003.1 - 0.054 12.9 1.8 0.38 10.1 1.1 2.1 1 1 0 2 2 2 0 AAA-like domain MMR_HSR1 PF01926.18 EXF86003.1 - 0.082 12.8 0.1 1 9.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase HI0933_like PF03486.9 EXF86003.1 - 0.11 10.8 0.4 0.64 8.4 0.0 2.3 3 0 0 3 3 3 0 HI0933-like protein SbcCD_C PF13558.1 EXF86003.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit IIGP PF05049.8 EXF86003.1 - 0.13 11.0 0.2 0.32 9.7 0.1 1.6 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) Miro PF08477.8 EXF86003.1 - 0.17 12.4 0.1 0.41 11.1 0.1 1.6 1 0 0 1 1 1 0 Miro-like protein FtsK_SpoIIIE PF01580.13 EXF86003.1 - 0.17 11.3 0.8 0.42 10.0 0.5 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family A_deamin PF02137.13 EXF86003.1 - 0.27 10.5 0.0 0.44 9.8 0.0 1.2 1 0 0 1 1 1 0 Adenosine-deaminase (editase) domain KaiC PF06745.8 EXF86003.1 - 0.29 10.2 0.0 0.56 9.2 0.0 1.4 1 0 0 1 1 1 0 KaiC T2SE PF00437.15 EXF86003.1 - 0.31 9.9 0.1 0.54 9.1 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF87 PF01935.12 EXF86003.1 - 2.4 7.9 3.3 4.3 7.0 2.3 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF87 HCO3_cotransp PF00955.16 EXF86004.1 - 2.3e-58 198.1 19.1 5.5e-34 117.6 5.5 2.1 1 1 1 2 2 2 2 HCO3- transporter family Herpes_US9 PF06072.6 EXF86004.1 - 0.049 13.4 0.5 0.2 11.5 0.4 2.1 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 Zn_clus PF00172.13 EXF86005.1 - 1.7e-10 40.6 10.1 1.7e-10 40.6 7.0 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF86005.1 - 0.00077 18.4 0.2 0.0013 17.6 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Glyco_hydro_3 PF00933.16 EXF86006.1 - 2.8e-85 285.9 0.0 4.1e-85 285.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF86006.1 - 1.2e-68 230.9 0.0 6.4e-68 228.6 0.0 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF86006.1 - 1.8e-25 88.6 0.6 4.8e-25 87.2 0.4 1.8 1 0 0 1 1 1 1 Fibronectin type III-like domain PA14 PF07691.7 EXF86006.1 - 7.2e-11 41.9 0.2 1.4e-10 40.9 0.2 1.4 1 0 0 1 1 1 1 PA14 domain Lipase_GDSL_2 PF13472.1 EXF86006.1 - 0.04 14.0 0.2 0.13 12.3 0.0 1.9 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Phage_tail_X PF05489.7 EXF86006.1 - 0.058 12.8 0.1 0.16 11.4 0.1 1.7 1 0 0 1 1 1 0 Phage Tail Protein X Bac_rhamnosid PF05592.6 EXF86007.1 - 1.9e-27 95.6 0.1 3.1e-18 65.2 0.0 2.1 2 0 0 2 2 2 2 Bacterial alpha-L-rhamnosidase Bac_rhamnosid_N PF08531.5 EXF86007.1 - 2.3e-06 27.2 0.0 4.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Alpha-L-rhamnosidase N-terminal domain PA14 PF07691.7 EXF86007.1 - 0.026 14.1 0.0 5.2 6.6 0.0 2.4 2 0 0 2 2 2 0 PA14 domain Sugar_tr PF00083.19 EXF86008.1 - 3e-74 250.2 17.2 3.5e-74 250.0 11.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF86008.1 - 5.2e-27 94.4 23.1 9.1e-27 93.6 10.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EXF86008.1 - 1.2e-05 23.9 1.9 1.2e-05 23.9 1.3 2.6 2 1 0 2 2 2 2 MFS/sugar transport protein DUF805 PF05656.9 EXF86008.1 - 0.39 10.5 5.9 0.32 10.8 0.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF805) NmrA PF05368.8 EXF86009.1 - 1.8e-10 40.5 0.0 2.4e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF86009.1 - 8.1e-07 29.2 1.0 2.7e-05 24.2 0.7 2.1 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EXF86009.1 - 3.4e-05 23.4 0.0 0.098 12.0 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EXF86009.1 - 5e-05 23.2 0.0 8.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF86009.1 - 0.00085 19.0 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Caps_synth PF05704.7 EXF86010.1 - 2.8e-15 56.2 0.1 5.4e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 Capsular polysaccharide synthesis protein Gly_transf_sug PF04488.10 EXF86010.1 - 3.9e-05 23.9 0.0 8.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Tetraspannin PF00335.15 EXF86011.1 - 0.032 13.4 17.2 0.77 8.9 11.9 2.1 1 1 0 1 1 1 0 Tetraspanin family Herpes_gE PF02480.11 EXF86011.1 - 0.038 12.2 0.1 0.1 10.8 0.1 1.7 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E OAD_gamma PF04277.8 EXF86011.1 - 0.047 14.0 0.7 11 6.4 0.0 2.5 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain MARVEL PF01284.18 EXF86011.1 - 0.32 10.7 17.1 0.03 14.1 4.2 2.1 1 1 1 2 2 2 0 Membrane-associating domain DUF2231 PF09990.4 EXF86011.1 - 0.55 10.6 6.5 0.23 11.8 2.7 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2231) GWT1 PF06423.7 EXF86011.1 - 0.8 9.7 5.5 0.53 10.3 2.3 1.7 1 1 0 1 1 1 0 GWT1 Virul_fac_BrkB PF03631.10 EXF86011.1 - 1.1 8.5 15.4 1.4 8.1 10.7 1.2 1 0 0 1 1 1 0 Virulence factor BrkB DUF418 PF04235.7 EXF86011.1 - 1.8 8.1 12.5 7.9 6.1 8.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF418) DUF1625 PF07787.7 EXF86011.1 - 2.1 7.5 7.0 3.2 6.9 4.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1625) FA_desaturase PF00487.19 EXF86011.1 - 7.1 5.9 7.3 12 5.2 5.0 1.5 1 1 0 1 1 1 0 Fatty acid desaturase Peptidase_M24 PF00557.19 EXF86012.1 - 6.4e-47 159.8 0.0 1.3e-45 155.5 0.0 2.1 1 1 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EXF86012.1 - 1.1e-25 89.5 0.0 3.1e-25 88.1 0.0 1.7 2 0 0 2 2 2 1 Aminopeptidase P, N-terminal domain Zn_clus PF00172.13 EXF86013.1 - 5.7e-05 22.9 10.5 0.00014 21.7 7.2 1.7 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF86013.1 - 0.00017 20.5 0.0 0.00036 19.5 0.0 1.5 1 0 0 1 1 1 1 Fungal specific transcription factor domain NPP1 PF05630.6 EXF86014.1 - 6e-33 114.3 0.0 1.2e-32 113.3 0.0 1.5 1 1 0 1 1 1 1 Necrosis inducing protein (NPP1) Glyco_hydro_1 PF00232.13 EXF86015.1 - 6.3e-144 479.5 2.0 7.9e-144 479.2 1.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 Topoisom_I_N PF02919.10 EXF86016.1 - 7.1e-97 322.8 5.9 7.1e-97 322.8 4.1 2.9 4 0 0 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EXF86016.1 - 2e-84 282.3 8.1 4.2e-84 281.3 5.6 1.6 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EXF86016.1 - 5.6e-30 102.8 0.3 5.6e-30 102.8 0.2 2.1 2 0 0 2 2 2 1 C-terminal topoisomerase domain RolB_RolC PF02027.12 EXF86016.1 - 0.041 13.0 0.1 0.088 11.9 0.1 1.5 1 0 0 1 1 1 0 RolB/RolC glucosidase family PspB PF06667.7 EXF86016.1 - 0.11 12.3 0.1 0.4 10.6 0.0 1.9 1 0 0 1 1 1 0 Phage shock protein B ATP-synt PF00231.14 EXF86017.1 - 1.1e-70 238.2 2.8 1.3e-70 238.0 1.9 1.0 1 0 0 1 1 1 1 ATP synthase Sec1 PF00995.18 EXF86018.1 - 2.1e-139 465.7 0.0 2.6e-139 465.4 0.0 1.1 1 0 0 1 1 1 1 Sec1 family Amino_oxidase PF01593.19 EXF86018.1 - 9.5e-81 272.1 0.1 1.9e-80 271.1 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase SWIRM PF04433.12 EXF86018.1 - 2.3e-10 40.4 0.0 5.9e-10 39.1 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain NAD_binding_8 PF13450.1 EXF86018.1 - 8.7e-07 28.8 0.0 3.3e-06 27.0 0.0 2.1 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HMG_box PF00505.14 EXF86018.1 - 3e-06 27.4 2.3 3e-06 27.4 1.6 2.1 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EXF86018.1 - 6.1e-05 23.3 3.2 0.00014 22.1 2.2 1.6 1 0 0 1 1 1 1 HMG-box domain NAD_binding_9 PF13454.1 EXF86018.1 - 0.058 13.1 0.5 2.7 7.7 0.0 3.4 4 0 0 4 4 4 0 FAD-NAD(P)-binding DAO PF01266.19 EXF86018.1 - 0.067 12.0 1.8 0.17 10.7 0.2 2.4 3 0 0 3 3 3 0 FAD dependent oxidoreductase UQ_con PF00179.21 EXF86019.1 - 2.9e-28 98.0 0.0 3.4e-28 97.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EXF86019.1 - 1.5e-07 31.2 0.0 2.8e-07 30.3 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EXF86019.1 - 8.6e-07 28.8 0.1 1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EXF86019.1 - 0.0019 17.8 0.1 0.0025 17.5 0.0 1.2 1 0 0 1 1 1 1 UEV domain Pkinase PF00069.20 EXF86020.1 - 4e-68 229.3 0.0 5.2e-68 229.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF86020.1 - 2.1e-30 105.6 0.3 4.2e-30 104.6 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF86020.1 - 0.0093 14.9 0.1 0.03 13.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Grp1_Fun34_YaaH PF01184.14 EXF86021.1 - 9.7e-78 260.2 16.8 1.2e-77 260.0 11.6 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family FAD_binding_2 PF00890.19 EXF86022.1 - 1.6e-66 224.9 4.1 1.8e-66 224.6 2.8 1.0 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EXF86022.1 - 2.5e-08 33.8 0.7 9.3e-08 31.9 0.5 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EXF86022.1 - 6.1e-08 31.9 0.0 1.2e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF86022.1 - 7.1e-07 29.3 0.7 1.5e-05 24.9 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EXF86022.1 - 1.3e-05 23.8 4.8 0.00029 19.4 0.4 3.0 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox_3 PF13738.1 EXF86022.1 - 1.5e-05 25.1 0.2 5.3e-05 23.3 0.1 2.0 1 1 2 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EXF86022.1 - 4.4e-05 22.7 0.7 7.2e-05 21.9 0.5 1.4 1 1 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EXF86022.1 - 7.1e-05 22.0 2.4 0.00016 20.9 1.7 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EXF86022.1 - 9.4e-05 21.6 0.2 0.0077 15.3 0.0 2.5 2 0 0 2 2 2 1 Thi4 family GIDA PF01134.17 EXF86022.1 - 0.00011 21.1 5.3 0.0007 18.5 0.3 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A Pyr_redox PF00070.22 EXF86022.1 - 0.001 19.4 0.0 0.0029 17.9 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EXF86022.1 - 0.0094 15.5 0.3 0.022 14.3 0.2 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.7 EXF86022.1 - 0.014 14.3 1.0 0.032 13.1 0.2 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein 3HCDH_N PF02737.13 EXF86022.1 - 0.038 13.6 0.2 0.063 12.9 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EXF86022.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding Peptidase_S8 PF00082.17 EXF86023.1 - 1.5e-48 165.3 15.0 2.2e-48 164.8 10.4 1.2 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.11 EXF86023.1 - 1.3e-07 32.0 0.1 4.1e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 Peptidase inhibitor I9 NMT1 PF09084.6 EXF86024.1 - 7.7e-78 260.9 0.0 9.9e-78 260.6 0.0 1.1 1 0 0 1 1 1 1 NMT1/THI5 like NMT1_2 PF13379.1 EXF86024.1 - 1.4e-08 34.4 0.4 0.026 13.9 0.0 3.7 2 1 2 4 4 4 3 NMT1-like family HIG_1_N PF04588.8 EXF86024.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Hypoxia induced protein conserved region HET PF06985.6 EXF86026.1 - 0.054 13.6 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Heterokaryon incompatibility protein (HET) Ferritin_2 PF13668.1 EXF86027.1 - 5.3e-05 23.1 0.0 8.3e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Ferritin-like domain AAA_22 PF13401.1 EXF86028.1 - 3.7e-08 33.5 0.1 1.2e-07 31.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EXF86028.1 - 5.4e-05 22.1 0.0 9.6e-05 21.3 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain NACHT PF05729.7 EXF86028.1 - 9.2e-05 22.1 0.0 0.00019 21.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EXF86028.1 - 0.003 17.5 5.1 0.0039 17.2 0.6 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EXF86028.1 - 0.016 16.0 0.4 0.07 13.9 0.3 2.1 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.9 EXF86028.1 - 0.049 12.6 0.4 5.7 5.8 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain DUF2039 PF10217.4 EXF86028.1 - 0.073 13.0 7.1 0.17 11.9 4.9 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) AAA_18 PF13238.1 EXF86028.1 - 0.092 13.0 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Peptidase_S41 PF03572.13 EXF86029.1 - 6.6e-06 25.6 0.0 1.6e-05 24.4 0.0 1.6 1 1 0 1 1 1 1 Peptidase family S41 CorA PF01544.13 EXF86030.1 - 6.2e-11 41.8 0.6 1.5e-10 40.6 0.4 1.6 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF676 PF05057.9 EXF86030.1 - 4.7e-06 26.0 0.0 9.3e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Tropomyosin_1 PF12718.2 EXF86030.1 - 0.38 10.5 15.6 0.78 9.5 10.8 1.6 1 0 0 1 1 1 0 Tropomyosin like F_bP_aldolase PF01116.15 EXF86032.1 - 1.4e-71 240.9 0.0 1.5e-71 240.8 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-II AF0941-like PF14591.1 EXF86033.1 - 0.12 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 AF0941-like HET PF06985.6 EXF86034.1 - 8.8e-20 71.2 5.2 5.3e-18 65.5 3.6 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Aminotran_3 PF00202.16 EXF86036.1 - 3.1e-96 322.1 0.0 3.9e-96 321.8 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EXF86036.1 - 0.04 12.8 0.0 0.069 12.0 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II FAD_binding_3 PF01494.14 EXF86037.1 - 7.5e-71 239.0 0.0 9.7e-71 238.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF86037.1 - 1.2e-06 27.6 0.0 0.0003 19.7 0.0 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EXF86037.1 - 1.7e-05 24.9 0.0 6.4e-05 23.0 0.0 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF86037.1 - 7.2e-05 22.6 0.0 0.00013 21.7 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EXF86037.1 - 0.00039 20.3 0.0 0.0012 18.8 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EXF86037.1 - 0.00045 19.2 0.2 0.012 14.5 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 EXF86037.1 - 0.00053 19.1 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.9 EXF86037.1 - 0.00073 18.1 0.0 0.022 13.2 0.0 2.1 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EXF86037.1 - 0.0011 19.3 0.0 0.028 14.8 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EXF86037.1 - 0.0028 16.5 0.0 0.004 16.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EXF86037.1 - 0.0077 16.1 0.0 0.017 15.0 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.13 EXF86037.1 - 0.021 14.7 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain K_oxygenase PF13434.1 EXF86037.1 - 0.15 10.9 0.0 0.28 10.0 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) BTB PF00651.26 EXF86038.1 - 0.00018 21.4 0.0 0.00034 20.5 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Glyco_hydro_43 PF04616.9 EXF86039.1 - 4.2e-14 52.3 0.7 7e-14 51.5 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 43 Glyco_hydro_32N PF00251.15 EXF86039.1 - 0.02 14.2 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolases family 32 N-terminal domain HET PF06985.6 EXF86041.1 - 1.4e-23 83.5 0.3 3e-23 82.5 0.2 1.6 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Ribonuclease PF00545.15 EXF86042.1 - 2.2e-15 56.4 0.1 3.4e-15 55.8 0.1 1.3 1 0 0 1 1 1 1 ribonuclease DUF3632 PF12311.3 EXF86043.1 - 1.2e-36 126.2 3.4 1.7e-36 125.7 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3632) ABC_tran PF00005.22 EXF86044.1 - 2.7e-53 179.9 0.0 3.8e-30 104.9 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.18 EXF86044.1 - 7.8e-25 87.8 29.9 2.9e-16 59.6 9.6 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.1 EXF86044.1 - 4.9e-11 43.1 0.0 0.019 14.9 0.0 4.2 3 1 0 4 4 4 3 AAA domain SMC_N PF02463.14 EXF86044.1 - 1.3e-10 40.9 0.3 0.00011 21.5 0.0 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EXF86044.1 - 8.6e-09 34.8 0.5 0.005 16.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EXF86044.1 - 2e-08 34.4 0.1 0.0032 17.6 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EXF86044.1 - 3.3e-08 33.7 5.0 0.0024 17.8 0.0 3.0 3 0 0 3 3 2 2 AAA ATPase domain AAA_17 PF13207.1 EXF86044.1 - 4.7e-07 30.6 0.0 0.064 14.0 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_10 PF12846.2 EXF86044.1 - 1.1e-06 28.3 0.0 0.047 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA-like domain AAA_23 PF13476.1 EXF86044.1 - 1.2e-06 28.9 0.1 0.027 14.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EXF86044.1 - 1.3e-06 27.7 0.1 0.0099 15.0 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EXF86044.1 - 2.1e-06 27.2 0.9 0.014 14.8 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EXF86044.1 - 3.5e-06 27.3 0.0 0.16 12.3 0.0 3.1 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 EXF86044.1 - 6.1e-06 26.7 0.3 0.083 13.3 0.0 2.8 3 0 0 3 3 2 2 Miro-like protein MMR_HSR1 PF01926.18 EXF86044.1 - 8.5e-06 25.7 0.1 0.17 11.8 0.0 2.8 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.1 EXF86044.1 - 1.4e-05 25.0 0.0 0.029 14.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain MobB PF03205.9 EXF86044.1 - 2e-05 24.3 0.2 0.44 10.2 0.0 3.2 3 0 0 3 3 3 2 Molybdopterin guanine dinucleotide synthesis protein B Dynamin_N PF00350.18 EXF86044.1 - 3.5e-05 23.6 0.0 0.018 14.8 0.0 2.7 2 0 0 2 2 2 1 Dynamin family cobW PF02492.14 EXF86044.1 - 3.7e-05 23.2 0.1 0.019 14.3 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_19 PF13245.1 EXF86044.1 - 8.9e-05 22.1 0.3 0.065 13.0 0.0 2.9 2 0 0 2 2 2 1 Part of AAA domain T2SE PF00437.15 EXF86044.1 - 9e-05 21.5 0.0 0.35 9.7 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein DUF87 PF01935.12 EXF86044.1 - 0.00017 21.4 1.1 0.008 16.0 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function DUF87 NACHT PF05729.7 EXF86044.1 - 0.0003 20.4 0.4 0.3 10.7 0.1 2.7 2 0 0 2 2 2 1 NACHT domain Adeno_IVa2 PF02456.10 EXF86044.1 - 0.0003 19.5 0.0 0.14 10.7 0.0 2.5 2 0 0 2 2 2 1 Adenovirus IVa2 protein FtsK_SpoIIIE PF01580.13 EXF86044.1 - 0.00049 19.6 0.1 0.064 12.7 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EXF86044.1 - 0.0011 18.0 0.2 0.42 9.6 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin Arch_ATPase PF01637.13 EXF86044.1 - 0.0014 18.3 0.0 0.22 11.1 0.0 2.9 3 0 0 3 3 3 1 Archaeal ATPase AAA_14 PF13173.1 EXF86044.1 - 0.002 18.0 0.0 1 9.2 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.1 EXF86044.1 - 0.0024 17.4 0.1 2.2 7.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 EXF86044.1 - 0.0092 15.4 0.0 1.1 8.6 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain SbcCD_C PF13558.1 EXF86044.1 - 0.012 15.5 0.2 7.6 6.5 0.0 3.0 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA PF00004.24 EXF86044.1 - 0.012 15.7 0.0 1.7 8.8 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PduV-EutP PF10662.4 EXF86044.1 - 0.04 13.3 0.1 1.5 8.2 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NB-ARC PF00931.17 EXF86044.1 - 0.045 12.6 0.0 6.1 5.6 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.10 EXF86044.1 - 0.061 13.0 0.4 7 6.3 0.0 2.6 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.17 EXF86044.1 - 0.062 13.4 0.0 18 5.5 0.0 2.7 2 0 0 2 2 2 0 RNA helicase AAA_5 PF07728.9 EXF86044.1 - 0.066 12.9 0.7 3.2 7.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EXF86044.1 - 0.07 12.0 0.2 11 4.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_24 PF13479.1 EXF86044.1 - 0.071 12.6 0.1 8.6 5.8 0.1 2.5 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EXF86044.1 - 0.087 12.3 0.2 3.5 7.1 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein UPF0079 PF02367.12 EXF86044.1 - 0.093 12.3 0.2 0.74 9.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 DAP3 PF10236.4 EXF86044.1 - 0.34 9.7 1.5 6.5 5.5 0.1 2.4 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_28 PF13521.1 EXF86044.1 - 0.37 10.7 1.7 14 5.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.7 EXF86044.1 - 0.4 9.9 0.3 21 4.2 0.0 2.3 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_15 PF13175.1 EXF86044.1 - 0.7 8.8 0.0 2.1 7.3 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain G-alpha PF00503.15 EXF86044.1 - 2.2 6.8 4.7 4.3 5.9 0.0 2.6 3 0 0 3 3 2 0 G-protein alpha subunit BatA PF07584.6 EXF86044.1 - 6 7.1 14.5 0.74 10.0 1.1 3.7 3 0 0 3 3 2 0 Aerotolerance regulator N-terminal RTA1 PF04479.8 EXF86045.1 - 3.3e-57 193.5 5.6 4.9e-57 193.0 3.9 1.2 1 0 0 1 1 1 1 RTA1 like protein Kelch_6 PF13964.1 EXF86046.1 - 5.2e-33 111.8 0.2 3e-09 36.6 0.0 6.5 3 2 3 6 6 6 5 Kelch motif Kelch_1 PF01344.20 EXF86046.1 - 2.7e-30 103.6 1.5 1.7e-06 27.4 0.0 6.9 6 1 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 EXF86046.1 - 6.3e-24 83.4 0.2 6.1e-07 29.1 0.0 6.0 4 1 2 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.10 EXF86046.1 - 4e-20 70.7 0.2 0.0014 18.3 0.0 6.6 6 2 0 6 6 6 4 Kelch motif Kelch_3 PF13415.1 EXF86046.1 - 4.5e-20 71.2 0.1 7.3e-05 22.8 0.0 5.6 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EXF86046.1 - 1.7e-16 59.7 1.4 0.0054 16.6 0.0 5.6 5 0 0 5 5 5 5 Kelch motif Fungal_trans_2 PF11951.3 EXF86046.1 - 1.7e-05 23.6 1.0 2.5e-05 23.0 0.7 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF86046.1 - 0.01 15.6 11.3 0.15 12.0 7.8 2.3 1 1 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain ADH_zinc_N_2 PF13602.1 EXF86047.1 - 3.9e-20 73.0 0.0 8.3e-20 71.9 0.0 1.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.21 EXF86047.1 - 7.5e-17 61.1 0.1 1.3e-16 60.3 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF86047.1 - 0.12 12.1 0.0 0.31 10.8 0.0 1.7 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain Tyrosinase PF00264.15 EXF86048.1 - 8e-39 134.0 0.2 1.1e-38 133.5 0.2 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Glyco_transf_8 PF01501.15 EXF86049.1 - 5e-24 84.9 0.0 7e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 LuxS PF02664.10 EXF86050.1 - 0.11 12.1 0.6 0.35 10.4 0.2 1.9 2 0 0 2 2 2 0 S-Ribosylhomocysteinase (LuxS) tRNA-synt_2c PF01411.14 EXF86051.1 - 4.6e-08 31.8 0.1 5.8e-08 31.4 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EXF86051.1 - 6.3e-06 25.9 0.5 1.1e-05 25.2 0.4 1.4 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Amidase PF01425.16 EXF86052.1 - 6.9e-102 341.5 0.0 8e-102 341.3 0.0 1.0 1 0 0 1 1 1 1 Amidase MFS_1 PF07690.11 EXF86053.1 - 7.9e-33 113.6 22.9 7.9e-33 113.6 15.9 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily 3HCDH_N PF02737.13 EXF86054.1 - 1e-31 109.9 0.0 1.5e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EXF86054.1 - 1e-14 54.7 0.0 1.9e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EXF86054.1 - 1.7e-06 27.8 0.0 2.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ldl_recept_b PF00058.12 EXF86054.1 - 0.0025 18.1 0.1 34 4.8 0.0 4.5 4 0 0 4 4 4 0 Low-density lipoprotein receptor repeat class B Str_synth PF03088.11 EXF86054.1 - 0.0036 17.2 0.0 2.2 8.3 0.0 3.2 2 1 0 2 2 2 2 Strictosidine synthase NAD_binding_2 PF03446.10 EXF86054.1 - 0.0073 16.1 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Beta-lactamase PF00144.19 EXF86055.1 - 9e-48 162.9 0.0 1.2e-47 162.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase DUF3471 PF11954.3 EXF86055.1 - 1.6e-05 24.6 0.0 3.2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3471) DUF4471 PF14740.1 EXF86055.1 - 0.014 14.6 0.0 0.023 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) BNR_2 PF13088.1 EXF86056.1 - 3.3e-06 26.6 0.1 0.001 18.4 0.0 2.8 1 1 1 2 2 2 2 BNR repeat-like domain BNR PF02012.15 EXF86056.1 - 0.0003 20.1 9.8 0.058 13.2 0.1 3.7 4 0 0 4 4 4 2 BNR/Asp-box repeat Fungal_trans_2 PF11951.3 EXF86057.1 - 0.0099 14.5 0.0 0.014 13.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF86057.1 - 0.017 15.0 2.9 0.033 14.0 2.0 1.4 1 0 0 1 1 1 0 Fungal Zn(2)-Cys(6) binuclear cluster domain GFO_IDH_MocA PF01408.17 EXF86058.1 - 2e-21 76.6 0.2 4.2e-21 75.6 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EXF86058.1 - 2.3e-07 30.5 0.0 4.4e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain HTH_3 PF01381.17 EXF86058.1 - 0.077 12.8 0.0 0.21 11.4 0.0 1.7 1 1 0 1 1 1 0 Helix-turn-helix Sugar_tr PF00083.19 EXF86059.1 - 5.9e-106 354.7 20.5 7.4e-106 354.4 14.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF86059.1 - 1.9e-24 86.0 52.7 1.1e-18 67.1 17.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF86059.1 - 3.7e-06 25.4 10.0 0.0019 16.5 2.3 2.1 2 0 0 2 2 2 2 Fungal trichothecene efflux pump (TRI12) DUF791 PF05631.9 EXF86059.1 - 3e-05 22.8 0.4 3e-05 22.8 0.3 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF791) UNC-93 PF05978.11 EXF86059.1 - 0.18 11.2 12.3 0.072 12.5 1.2 2.8 3 0 0 3 3 3 0 Ion channel regulatory protein UNC-93 GFO_IDH_MocA PF01408.17 EXF86060.1 - 7.8e-22 78.0 0.1 1.1e-20 74.2 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Gp_dh_N PF00044.19 EXF86060.1 - 0.0052 16.7 0.0 0.012 15.6 0.0 1.7 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EXF86060.1 - 0.065 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_hydro_7 PF00840.15 EXF86061.1 - 3.1e-94 315.8 0.1 2e-54 184.6 1.1 2.0 1 1 1 2 2 2 2 Glycosyl hydrolase family 7 DUF1628 PF07790.6 EXF86061.1 - 0.13 12.9 0.2 1.1 10.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1628) RPE65 PF03055.10 EXF86062.1 - 1e-117 393.7 0.0 1.3e-117 393.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Glyco_hydro_17 PF00332.13 EXF86063.1 - 6.8e-25 87.7 0.1 3.3e-23 82.1 0.0 2.0 1 1 0 1 1 1 1 Glycosyl hydrolases family 17 Asp PF00026.18 EXF86064.1 - 8.2e-59 199.4 4.3 1e-58 199.1 3.0 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EXF86064.1 - 1.5e-10 41.3 0.4 3.2e-09 36.9 0.1 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EXF86064.1 - 1.5e-05 25.3 0.3 0.18 12.2 0.0 3.1 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.1 EXF86064.1 - 0.0069 15.9 0.1 0.07 12.6 0.0 2.3 1 1 1 2 2 2 1 Xylanase inhibitor C-terminal ADH_zinc_N PF00107.21 EXF86067.1 - 1.2e-22 79.8 0.2 1.8e-22 79.3 0.1 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF86067.1 - 1.7e-17 63.1 0.1 3.8e-17 62.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EXF86067.1 - 4.7e-06 27.5 0.1 8.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF359 PF04019.7 EXF86067.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF359) 4HBT PF03061.17 EXF86068.1 - 5.1e-06 26.5 0.0 8.6e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EXF86068.1 - 0.069 13.1 0.1 0.13 12.2 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4442) p450 PF00067.17 EXF86069.1 - 3.9e-56 190.4 0.0 5.2e-56 190.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 YL1_C PF08265.6 EXF86069.1 - 0.065 12.7 0.1 0.19 11.3 0.0 1.8 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain DUF500 PF04366.7 EXF86071.1 - 3.6e-44 149.2 0.0 5.5e-44 148.6 0.0 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF500) DUF604 PF04646.7 EXF86072.1 - 1.6e-07 30.7 0.0 3.5e-06 26.4 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function, DUF604 Fringe PF02434.11 EXF86072.1 - 3.1e-06 26.6 0.0 6.1e-06 25.6 0.0 1.5 1 1 0 1 1 1 1 Fringe-like BRO1 PF03097.13 EXF86073.1 - 2.1e-112 375.6 0.0 4.1e-112 374.6 0.0 1.5 1 0 0 1 1 1 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EXF86073.1 - 6e-83 278.2 4.0 6e-83 278.2 2.8 1.7 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV R3H-assoc PF13902.1 EXF86073.1 - 0.0086 16.0 1.4 0.034 14.1 1.0 2.1 1 0 0 1 1 1 1 R3H-associated N-terminal domain A_deaminase PF00962.17 EXF86073.1 - 0.051 12.4 0.1 0.079 11.8 0.0 1.3 1 0 0 1 1 1 0 Adenosine/AMP deaminase DHC_N1 PF08385.7 EXF86073.1 - 0.071 11.4 1.8 5 5.3 0.0 2.4 2 0 0 2 2 2 0 Dynein heavy chain, N-terminal region 1 HATPase_c PF02518.21 EXF86074.1 - 9.4e-22 76.8 0.0 2e-21 75.7 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EXF86074.1 - 1.2e-17 63.8 0.0 2.6e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EXF86074.1 - 1.5e-13 50.5 0.0 4.8e-13 48.8 0.0 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GAF PF01590.21 EXF86074.1 - 4e-05 23.7 0.1 0.00016 21.7 0.0 2.1 2 0 0 2 2 2 1 GAF domain GAF_2 PF13185.1 EXF86074.1 - 0.0012 19.3 0.0 0.015 15.7 0.0 2.8 3 0 0 3 3 3 1 GAF domain HATPase_c_2 PF13581.1 EXF86074.1 - 0.086 12.6 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Abhydrolase_3 PF07859.8 EXF86075.1 - 1e-54 185.3 0.0 1.4e-54 184.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.23 EXF86075.1 - 6.1e-10 38.4 0.1 1.4e-09 37.1 0.1 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_6 PF12697.2 EXF86075.1 - 0.0054 16.6 0.4 0.0097 15.7 0.3 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF86075.1 - 0.011 15.0 0.1 0.23 10.6 0.0 2.2 1 1 0 1 1 1 0 Prolyl oligopeptidase family Glyco_hydro_88 PF07470.8 EXF86076.1 - 5.8e-59 199.8 4.3 7.3e-59 199.4 3.0 1.0 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 C5-epim_C PF06662.8 EXF86076.1 - 0.0017 17.7 0.4 0.05 12.8 0.1 2.6 1 1 1 2 2 2 1 D-glucuronyl C5-epimerase C-terminus DUF1680 PF07944.7 EXF86076.1 - 0.0031 15.8 0.0 0.0044 15.3 0.0 1.1 1 0 0 1 1 1 1 Putative glycosyl hydrolase of unknown function (DUF1680) Glyco_hydro_76 PF03663.9 EXF86076.1 - 0.064 12.6 1.7 0.13 11.6 0.2 2.0 2 0 0 2 2 2 0 Glycosyl hydrolase family 76 Gag_spuma PF03276.9 EXF86078.1 - 3.1 6.0 9.7 3.9 5.7 6.7 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Metallophos PF00149.23 EXF86079.1 - 9.6e-11 41.4 0.6 1.6e-10 40.7 0.4 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase HET PF06985.6 EXF86080.1 - 1.6e-21 76.9 5.4 1.3e-19 70.7 3.7 2.5 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) SR-25 PF10500.4 EXF86080.1 - 0.84 9.0 8.9 1.3 8.3 6.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF515 PF04415.7 EXF86080.1 - 1.9 6.6 3.1 2.8 6.0 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) F-box PF00646.28 EXF86081.1 - 0.0017 17.9 0.0 0.0042 16.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EXF86081.1 - 0.0054 16.4 0.0 0.02 14.6 0.0 2.0 2 0 0 2 2 2 1 F-box-like MFS_1 PF07690.11 EXF86082.1 - 7.6e-13 47.9 35.4 1.2e-08 34.0 14.0 3.0 2 1 1 3 3 3 2 Major Facilitator Superfamily Nodulin-like PF06813.8 EXF86082.1 - 1e-05 24.9 9.6 0.0096 15.2 0.4 3.2 3 1 1 4 4 4 2 Nodulin-like DUF2880 PF11082.3 EXF86084.1 - 0.074 12.9 0.4 0.13 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2880) DUF4551 PF15087.1 EXF86084.1 - 3.7 5.7 4.9 3.9 5.7 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) vMSA PF00695.14 EXF86084.1 - 6.6 5.8 8.9 7.9 5.5 6.1 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Pkinase PF00069.20 EXF86085.1 - 1.4e-24 86.6 0.0 2.1e-24 86.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF86085.1 - 1.8e-11 43.6 0.0 2.7e-10 39.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pyr_redox_3 PF13738.1 EXF86087.1 - 3.8e-27 95.6 0.0 1.2e-26 94.0 0.0 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EXF86087.1 - 7.6e-06 25.0 0.0 2.5e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FMO-like PF00743.14 EXF86087.1 - 0.00011 20.5 0.0 0.0023 16.2 0.0 2.1 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EXF86087.1 - 0.00023 21.1 0.2 0.00062 19.7 0.1 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EXF86087.1 - 0.0024 17.8 0.0 0.01 15.7 0.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Shikimate_DH PF01488.15 EXF86087.1 - 0.023 14.7 0.0 1.2 9.2 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Methyltransf_11 PF08241.7 EXF86089.1 - 7.8e-13 48.7 0.0 1.4e-12 47.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF86089.1 - 4.7e-12 46.4 0.0 9.4e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF86089.1 - 1.7e-09 37.6 0.0 2.2e-09 37.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF86089.1 - 5.8e-09 35.7 0.0 8.3e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF86089.1 - 8.5e-09 35.6 0.0 1.7e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF86089.1 - 1.5e-08 35.0 0.0 2.5e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EXF86089.1 - 1.3e-06 27.7 0.0 1.7e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.9 EXF86089.1 - 2.5e-05 23.7 0.0 3.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EXF86089.1 - 0.0002 21.3 0.1 0.00062 19.7 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF86089.1 - 0.00038 19.6 0.1 0.0007 18.7 0.1 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 EXF86089.1 - 0.00041 19.7 0.0 0.0006 19.2 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW CMAS PF02353.15 EXF86089.1 - 0.0014 17.7 0.0 0.0021 17.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TPMT PF05724.6 EXF86089.1 - 0.0099 15.3 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_16 PF10294.4 EXF86089.1 - 0.018 14.4 0.3 0.034 13.5 0.2 1.4 1 1 0 1 1 1 0 Putative methyltransferase ADH_zinc_N PF00107.21 EXF86089.1 - 0.086 12.3 0.1 0.32 10.5 0.1 1.9 1 1 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_29 PF03141.11 EXF86089.1 - 0.17 10.1 0.0 0.22 9.8 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Fungal_trans PF04082.13 EXF86090.1 - 4.3e-27 94.6 0.0 7.1e-27 93.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF86090.1 - 4.9e-08 32.7 13.7 1.2e-07 31.5 9.5 1.6 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Spc24 PF08286.6 EXF86090.1 - 0.22 11.2 0.7 0.39 10.4 0.5 1.3 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 Zip PF02535.17 EXF86091.1 - 7.5e-50 169.7 0.0 8.8e-50 169.5 0.0 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Cation_efflux PF01545.16 EXF86092.1 - 3.3e-36 124.8 9.2 4e-36 124.5 6.4 1.1 1 0 0 1 1 1 1 Cation efflux family SHNi-TPR PF10516.4 EXF86093.1 - 0.059 12.6 0.0 0.12 11.6 0.0 1.4 1 0 0 1 1 1 0 SHNi-TPR Hexapep PF00132.19 EXF86094.1 - 2.6e-08 33.0 12.0 4.6e-06 25.8 1.8 3.7 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EXF86094.1 - 5e-07 29.1 12.0 0.0015 17.9 0.9 2.8 2 1 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Complex1_51K PF01512.12 EXF86095.1 - 2.2e-47 160.5 0.0 3.3e-47 159.9 0.0 1.3 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EXF86095.1 - 9.3e-19 66.3 0.4 9.3e-19 66.3 0.3 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EXF86095.1 - 6.1e-09 35.6 0.0 1.3e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 SLBB domain PEX11 PF05648.9 EXF86096.1 - 6.3e-15 55.0 0.0 1.8e-12 47.0 0.0 3.1 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) HAUS5 PF14817.1 EXF86096.1 - 0.21 10.1 1.4 0.28 9.6 1.0 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 5 Smr PF01713.16 EXF86098.1 - 1.1e-09 38.3 0.2 3.5e-09 36.7 0.2 1.9 1 0 0 1 1 1 1 Smr domain CUE PF02845.11 EXF86098.1 - 1.1e-06 27.9 0.6 0.00045 19.6 0.1 3.0 3 0 0 3 3 3 2 CUE domain BMFP PF04380.8 EXF86098.1 - 0.11 12.6 0.0 0.3 11.2 0.0 1.7 1 0 0 1 1 1 0 Membrane fusogenic activity Amidase PF01425.16 EXF86099.1 - 2.8e-76 257.1 0.0 4.1e-76 256.6 0.0 1.2 1 0 0 1 1 1 1 Amidase Acyltransferase PF01553.16 EXF86100.1 - 2.1e-11 43.3 0.0 8.9e-06 25.1 0.0 2.3 2 0 0 2 2 2 2 Acyltransferase Suc_Fer-like PF06999.7 EXF86101.1 - 1.2e-32 113.7 0.0 2e-32 113.0 0.0 1.4 1 1 0 1 1 1 1 Sucrase/ferredoxin-like Drf_GBD PF06371.8 EXF86102.1 - 7.4e-16 58.0 1.5 1.5e-14 53.7 1.0 2.3 1 1 0 1 1 1 1 Diaphanous GTPase-binding Domain Methyltransf_6 PF03737.10 EXF86103.1 - 3.8e-18 65.8 0.5 5.1e-18 65.4 0.4 1.1 1 0 0 1 1 1 1 Demethylmenaquinone methyltransferase UCR_hinge PF02320.11 EXF86105.1 - 2.2e-26 91.5 8.5 6.8e-26 90.0 5.9 1.9 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein WWbp PF10349.4 EXF86105.1 - 1.5e-07 32.2 4.1 1.5e-07 32.2 2.9 3.4 3 2 0 3 3 1 1 WW-domain ligand protein Vps36_ESCRT-II PF11605.3 EXF86105.1 - 0.039 13.7 0.0 0.087 12.6 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 CENP-T PF15511.1 EXF86105.1 - 0.053 12.7 22.4 0.13 11.4 15.5 1.6 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Ycf1 PF05758.7 EXF86105.1 - 0.46 8.1 8.5 0.63 7.6 5.9 1.1 1 0 0 1 1 1 0 Ycf1 Asp-B-Hydro_N PF05279.6 EXF86105.1 - 0.56 10.0 21.1 0.96 9.2 14.6 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Nop14 PF04147.7 EXF86105.1 - 0.74 7.6 21.4 1.1 7.0 14.9 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EXF86105.1 - 0.91 7.4 11.4 1.3 6.9 7.9 1.2 1 0 0 1 1 1 0 CDC45-like protein Merozoite_SPAM PF07133.6 EXF86105.1 - 1.5 8.7 29.3 2.5 7.9 20.3 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DDHD PF02862.12 EXF86105.1 - 2.7 7.7 8.6 6.1 6.5 6.0 1.6 1 0 0 1 1 1 0 DDHD domain TLP-20 PF06088.6 EXF86105.1 - 3.1 7.4 6.0 6.5 6.3 4.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Sigma70_ner PF04546.8 EXF86105.1 - 3.6 7.1 21.9 0.29 10.7 11.7 1.8 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF1510 PF07423.6 EXF86105.1 - 4.1 6.7 19.8 7.5 5.8 13.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) BUD22 PF09073.5 EXF86105.1 - 5.9 5.8 22.9 1.3 7.9 11.4 2.1 2 0 0 2 2 2 0 BUD22 AIF_C PF14721.1 EXF86105.1 - 8.2 6.6 6.9 22 5.2 4.8 1.7 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Aminotran_5 PF00266.14 EXF86106.1 - 8.5e-09 34.6 0.0 3.4e-06 26.0 0.0 2.6 2 1 0 2 2 2 2 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EXF86106.1 - 0.00019 19.8 0.0 0.00031 19.1 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.12 EXF86106.1 - 0.0081 15.2 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SAM_2 PF07647.12 EXF86108.1 - 1.2e-16 60.2 0.0 2.5e-16 59.2 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EXF86108.1 - 1.9e-15 56.7 0.0 3.4e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RA PF00788.18 EXF86108.1 - 1.2e-13 51.3 0.0 2.6e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Lebercilin PF15619.1 EXF86109.1 - 0.0016 17.9 24.6 0.0044 16.4 3.8 2.2 2 0 0 2 2 2 2 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.1 EXF86109.1 - 0.016 14.3 24.7 0.11 11.6 9.0 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding MCPsignal PF00015.16 EXF86109.1 - 0.019 14.5 2.3 0.028 13.9 1.4 1.4 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3584 PF12128.3 EXF86109.1 - 0.026 11.8 19.9 0.055 10.8 13.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.7 EXF86109.1 - 0.034 13.9 5.2 0.14 11.9 2.3 2.3 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Mnd1 PF03962.10 EXF86109.1 - 0.082 12.5 17.8 0.3 10.7 4.5 2.2 2 0 0 2 2 2 0 Mnd1 family IncA PF04156.9 EXF86109.1 - 0.087 12.4 27.5 0.26 10.8 3.9 2.2 1 1 1 2 2 2 0 IncA protein Reo_sigmaC PF04582.7 EXF86109.1 - 0.12 11.5 8.2 0.24 10.5 1.2 2.8 1 1 2 3 3 3 0 Reovirus sigma C capsid protein Cortex-I_coil PF09304.5 EXF86109.1 - 0.13 12.3 26.4 0.12 12.4 4.9 4.1 1 1 2 3 3 3 0 Cortexillin I, coiled coil DUF342 PF03961.8 EXF86109.1 - 0.17 10.2 19.3 0.042 12.2 5.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF342) Tweety PF04906.8 EXF86109.1 - 0.17 10.2 2.3 0.16 10.3 0.7 1.5 1 1 1 2 2 2 0 Tweety APG6 PF04111.7 EXF86109.1 - 0.26 10.2 22.3 0.51 9.3 13.7 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 GTPase_Cys_C PF12631.2 EXF86109.1 - 0.6 10.5 3.7 2.5 8.5 0.8 2.7 1 1 2 3 3 2 0 Catalytic cysteine-containing C-terminus of GTPase, MnmE DUF148 PF02520.12 EXF86109.1 - 0.61 9.8 8.6 0.17 11.6 2.8 2.3 3 0 0 3 3 3 0 Domain of unknown function DUF148 PEP-utilisers_N PF05524.8 EXF86109.1 - 0.69 9.7 8.2 0.67 9.7 1.6 2.3 1 1 1 2 2 2 0 PEP-utilising enzyme, N-terminal PMEI PF04043.10 EXF86109.1 - 0.9 9.4 7.3 3.4 7.5 0.5 2.5 1 1 1 2 2 2 0 Plant invertase/pectin methylesterase inhibitor Mt_ATP-synt_D PF05873.7 EXF86109.1 - 0.91 9.1 7.7 1.9 8.0 0.9 2.3 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) Fib_alpha PF08702.5 EXF86109.1 - 0.97 9.5 16.7 0.97 9.5 2.3 2.2 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF4201 PF13870.1 EXF86109.1 - 0.98 8.8 22.5 0.57 9.5 8.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Sec8_exocyst PF04048.9 EXF86109.1 - 1.1 8.8 12.1 0.4 10.3 4.1 2.5 1 1 0 2 2 2 0 Sec8 exocyst complex component specific domain DUF883 PF05957.8 EXF86109.1 - 1.1 9.6 13.7 0.59 10.5 3.7 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF3391 PF11871.3 EXF86109.1 - 1.1 9.4 7.5 11 6.2 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3391) DUF4047 PF13256.1 EXF86109.1 - 1.6 8.6 6.4 0.48 10.3 2.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) Flagellar_rod PF05149.7 EXF86109.1 - 1.7 7.7 17.8 0.95 8.5 4.7 2.3 2 0 0 2 2 2 0 Paraflagellar rod protein Spc7 PF08317.6 EXF86109.1 - 2.4 6.7 20.9 5.6 5.5 12.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Seryl_tRNA_N PF02403.17 EXF86109.1 - 2.8 8.0 20.9 0.52 10.3 8.1 2.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Cep57_CLD_2 PF14197.1 EXF86109.1 - 3.2 7.7 30.3 0.068 13.1 6.2 4.5 2 2 1 3 3 3 0 Centrosome localisation domain of PPC89 OmpH PF03938.9 EXF86109.1 - 4.1 7.3 17.4 1.6e+02 2.1 12.0 2.3 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) TPR_MLP1_2 PF07926.7 EXF86109.1 - 5.2 6.8 24.6 1.4 8.6 2.6 2.8 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein zf-C4H2 PF10146.4 EXF86109.1 - 5.6 6.9 15.0 11 5.9 10.4 1.5 1 1 0 1 1 1 0 Zinc finger-containing protein DUF4140 PF13600.1 EXF86109.1 - 5.8 7.4 17.8 9.3 6.7 0.8 3.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF972 PF06156.8 EXF86109.1 - 7.3 6.9 17.8 2.1 8.7 0.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF972) FliJ PF02050.11 EXF86109.1 - 9 6.3 15.2 3.5 7.7 3.9 3.0 1 1 2 4 4 4 0 Flagellar FliJ protein DUF3811 PF11656.3 EXF86109.1 - 9.8 6.3 14.7 0.067 13.2 3.4 2.4 3 0 0 3 3 2 0 YjbD family (DUF3811) Tom22 PF04281.8 EXF86110.1 - 3.5e-38 130.2 0.0 4.2e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 D5_N PF08706.6 EXF86112.1 - 0.097 12.7 2.2 0.35 10.9 1.8 1.7 2 0 0 2 2 2 0 D5 N terminal like DUF2461 PF09365.5 EXF86112.1 - 0.14 11.4 4.0 0.25 10.7 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical protein (DUF2461) DUF809 PF05663.6 EXF86114.1 - 0.0055 16.6 0.2 0.0055 16.6 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF809) EMP24_GP25L PF01105.19 EXF86115.1 - 3.8e-53 179.9 0.0 4.3e-53 179.7 0.0 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PPR_2 PF13041.1 EXF86116.1 - 9.5e-22 76.7 0.0 1.4e-06 28.1 0.0 5.5 4 1 1 5 5 5 4 PPR repeat family PPR_1 PF12854.2 EXF86116.1 - 3.5e-20 71.1 0.0 2.6e-06 26.7 0.0 5.5 5 0 0 5 5 5 5 PPR repeat PPR_3 PF13812.1 EXF86116.1 - 7.2e-14 50.8 1.9 0.043 14.1 0.0 6.3 5 0 0 5 5 5 4 Pentatricopeptide repeat domain PPR PF01535.15 EXF86116.1 - 2e-12 46.1 0.3 0.01 15.7 0.0 5.8 5 1 0 5 5 5 3 PPR repeat cwf18 PF08315.7 EXF86117.1 - 1.7e-44 151.3 6.1 1.7e-44 151.3 4.2 1.8 2 0 0 2 2 2 1 cwf18 pre-mRNA splicing factor Pam16 PF03656.8 EXF86117.1 - 0.26 11.1 3.7 0.29 10.9 1.3 2.0 1 1 1 2 2 2 0 Pam16 zf-CCHC_3 PF13917.1 EXF86118.1 - 2.4e-14 52.7 5.6 1.2e-10 40.9 0.6 2.7 2 0 0 2 2 2 2 Zinc knuckle SUZ PF12752.2 EXF86119.1 - 9.5e-15 54.8 4.0 9.5e-15 54.8 2.8 3.2 4 0 0 4 4 4 1 SUZ domain R3H PF01424.17 EXF86119.1 - 2.5e-07 30.2 0.0 5.5e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 R3H domain JAB PF01398.16 EXF86120.1 - 6.3e-14 51.6 0.0 1.1e-13 50.8 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EXF86120.1 - 1.2e-11 44.7 0.1 1.9e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function DUF3113 PF11310.3 EXF86120.1 - 0.085 12.5 0.0 0.21 11.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3113) DUF1253 PF06862.7 EXF86121.1 - 2.4e-163 543.6 0.1 3.4e-163 543.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1253) Ribosomal_L17 PF01196.14 EXF86122.1 - 2.6e-31 108.0 1.2 4.1e-31 107.4 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L17 BBP1_C PF15272.1 EXF86122.1 - 0.041 13.4 0.1 0.069 12.7 0.1 1.3 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Borrelia_P83 PF05262.6 EXF86123.1 - 0.0079 14.5 7.6 0.009 14.3 5.3 1.1 1 0 0 1 1 1 1 Borrelia P83/100 protein Apolipoprotein PF01442.13 EXF86123.1 - 7 6.1 16.4 1.1 8.7 8.5 1.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain Aldedh PF00171.17 EXF86125.1 - 2.7e-84 283.1 0.0 3e-84 282.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EXF86125.1 - 0.023 13.4 0.0 0.029 13.0 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) RDM PF11002.3 EXF86125.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.5 1 0 0 1 1 1 0 RFPL defining motif (RDM) MRP-S28 PF10213.4 EXF86126.1 - 2.1e-46 157.1 0.5 2.1e-46 157.1 0.4 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein Ank_2 PF12796.2 EXF86127.1 - 3e-71 235.7 7.4 1.5e-17 63.7 0.1 7.2 4 2 2 7 7 6 6 Ankyrin repeats (3 copies) Ank PF00023.25 EXF86127.1 - 6.3e-55 180.3 14.6 1.3e-06 27.9 0.0 13.5 15 0 0 15 15 14 8 Ankyrin repeat Ank_4 PF13637.1 EXF86127.1 - 1.2e-49 165.8 4.6 3.8e-08 33.6 0.0 10.3 5 3 6 11 11 11 11 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF86127.1 - 1.8e-44 145.2 7.9 0.00034 20.5 0.0 13.4 15 0 0 15 15 12 7 Ankyrin repeat Ank_5 PF13857.1 EXF86127.1 - 2e-41 139.0 12.1 7.7e-09 35.5 0.2 11.2 3 3 9 12 12 12 10 Ankyrin repeats (many copies) AAA_16 PF13191.1 EXF86127.1 - 7.5e-06 26.0 0.3 3.7e-05 23.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Abhydrolase_6 PF12697.2 EXF86127.1 - 6.3e-05 22.9 0.0 0.00039 20.3 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family AAA_22 PF13401.1 EXF86127.1 - 7.6e-05 22.8 0.0 0.00036 20.6 0.0 2.2 2 0 0 2 2 1 1 AAA domain DUF676 PF05057.9 EXF86127.1 - 0.00063 19.1 0.0 0.0014 17.9 0.0 1.5 1 0 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EXF86127.1 - 0.00064 19.3 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.15 EXF86127.1 - 0.00098 19.4 1.0 0.91 9.6 0.0 3.9 3 1 0 3 3 3 1 Thioesterase domain Abhydrolase_5 PF12695.2 EXF86127.1 - 0.0012 18.5 0.0 0.0033 17.1 0.0 1.7 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EXF86127.1 - 0.0079 15.8 0.0 0.021 14.4 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) Cutinase PF01083.17 EXF86127.1 - 0.033 13.9 0.1 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 Cutinase BUD22 PF09073.5 EXF86127.1 - 2.8 6.9 26.9 0.33 9.9 9.6 2.4 2 0 0 2 2 2 0 BUD22 CDC45 PF02724.9 EXF86127.1 - 5.9 4.7 23.8 0.63 8.0 7.4 2.3 2 0 0 2 2 2 0 CDC45-like protein Glyco_tran_28_C PF04101.11 EXF86129.1 - 4.7e-18 65.3 0.0 1.1e-17 64.1 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EXF86129.1 - 0.0035 16.5 0.0 0.0043 16.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 1 K_channel_TID PF07941.6 EXF86129.1 - 0.27 11.4 4.4 0.59 10.3 3.0 1.5 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain WD40 PF00400.27 EXF86130.1 - 1.3e-48 161.2 33.8 4.6e-09 35.8 0.1 10.8 11 1 0 11 11 11 8 WD domain, G-beta repeat CPSF_A PF03178.10 EXF86130.1 - 0.0002 20.5 0.0 0.0023 17.0 0.0 2.4 3 0 0 3 3 3 1 CPSF A subunit region Nbas_N PF15492.1 EXF86130.1 - 0.00021 20.5 0.8 1.1 8.2 0.1 3.5 2 1 0 3 3 3 2 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.7 EXF86130.1 - 0.0012 18.4 0.0 11 5.8 0.0 3.9 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EXF86130.1 - 0.0032 17.2 0.7 1.4 8.6 0.0 4.0 3 3 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A SNF2_N PF00176.18 EXF86131.1 - 4.1e-83 278.6 0.2 7.2e-83 277.8 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EXF86131.1 - 2.3e-44 149.8 2.0 8.1e-44 148.1 1.4 2.0 1 0 0 1 1 1 1 SLIDE HAND PF09110.6 EXF86131.1 - 4.8e-32 110.6 5.1 4.8e-32 110.6 3.6 4.1 4 0 0 4 4 4 1 HAND Helicase_C PF00271.26 EXF86131.1 - 1.4e-14 53.6 0.1 7.8e-14 51.2 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EXF86131.1 - 2.6e-09 37.1 0.0 3e-08 33.7 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EXF86131.1 - 9e-05 22.0 0.0 0.00023 20.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Myb_DNA-bind_6 PF13921.1 EXF86131.1 - 0.015 15.3 0.4 1 9.5 0.2 3.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EXF86131.1 - 0.018 15.0 0.0 1.5 8.9 0.0 3.4 3 0 0 3 3 3 0 Myb-like DNA-binding domain DEAD_2 PF06733.10 EXF86131.1 - 0.03 13.7 0.3 0.069 12.5 0.2 1.5 1 0 0 1 1 1 0 DEAD_2 DUF4588 PF15251.1 EXF86132.1 - 0.00091 19.2 18.3 0.0062 16.5 12.7 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) WD40 PF00400.27 EXF86133.1 - 9.8e-28 95.0 1.0 5e-10 38.8 0.1 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EXF86133.1 - 0.0004 19.2 0.0 0.002 16.9 0.0 1.9 1 1 1 2 2 2 2 Nup133 N terminal like eIF2A PF08662.6 EXF86133.1 - 0.0019 17.9 0.0 0.63 9.7 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.1 EXF86133.1 - 0.006 16.0 0.3 0.37 10.1 0.2 2.3 1 1 1 2 2 2 2 PQQ-like domain Nup160 PF11715.3 EXF86133.1 - 0.0079 14.3 0.0 0.0097 14.0 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Coatomer_WDAD PF04053.9 EXF86133.1 - 0.019 13.7 0.1 0.19 10.5 0.0 2.0 1 1 1 2 2 2 0 Coatomer WD associated region FTHFS PF01268.14 EXF86134.1 - 3e-256 850.7 0.2 4.4e-256 850.2 0.1 1.2 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase THF_DHG_CYH_C PF02882.14 EXF86134.1 - 2.7e-67 224.8 2.8 3.1e-67 224.6 0.5 2.1 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EXF86134.1 - 1.7e-37 127.9 0.5 4.4e-37 126.6 0.4 1.8 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Asp PF00026.18 EXF86136.1 - 6.9e-49 166.8 0.0 6.9e-49 166.8 0.0 1.5 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EXF86136.1 - 1.9e-09 37.6 0.0 1.9e-09 37.6 0.0 2.4 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EXF86136.1 - 0.0029 18.0 0.4 2.6 8.6 0.0 3.4 3 0 0 3 3 3 2 Aspartyl protease TAXi_C PF14541.1 EXF86136.1 - 0.016 14.7 0.2 0.12 11.8 0.1 2.3 2 1 0 2 2 2 0 Xylanase inhibitor C-terminal ATP12 PF07542.6 EXF86138.1 - 2.2e-29 101.8 0.0 4.4e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 ATP12 chaperone protein DUF596 PF04591.7 EXF86139.1 - 0.034 14.0 0.1 0.05 13.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF596 Pkinase PF00069.20 EXF86141.1 - 1.2e-57 195.0 0.0 8.3e-57 192.2 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF86141.1 - 2.3e-28 98.9 0.4 1.2e-19 70.3 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EXF86141.1 - 8.3e-07 29.4 0.4 2.1e-06 28.1 0.3 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EXF86141.1 - 0.00045 19.2 0.1 0.0026 16.7 0.0 2.2 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EXF86141.1 - 0.0052 16.5 0.0 0.084 12.5 0.0 2.4 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EXF86141.1 - 0.079 12.0 0.0 0.19 10.7 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Wbp11 PF09429.5 EXF86142.1 - 4.6e-22 77.7 8.6 4.6e-22 77.7 5.9 2.8 3 1 0 3 3 3 1 WW domain binding protein 11 DUF3306 PF11748.3 EXF86142.1 - 0.29 11.8 11.2 0.65 10.6 3.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) bZIP_2 PF07716.10 EXF86143.1 - 2.4e-07 30.4 5.1 3.9e-07 29.8 3.5 1.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_1 PF00170.16 EXF86143.1 - 0.00024 20.9 5.3 0.00038 20.3 3.6 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.12 EXF86143.1 - 0.0028 17.8 3.8 0.0061 16.8 2.6 1.5 1 0 0 1 1 1 1 bZIP Maf transcription factor Zn_clus PF00172.13 EXF86144.1 - 3.3e-09 36.4 7.7 5.2e-09 35.8 5.4 1.2 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4315 PF14193.1 EXF86144.1 - 0.0033 17.3 0.0 0.0057 16.5 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4315) CCAP PF11105.3 EXF86144.1 - 0.028 14.1 2.3 1.1 8.9 0.0 2.4 1 1 1 2 2 2 0 Arthropod cardioacceleratory peptide 2a Velvet PF11754.3 EXF86147.1 - 5.4e-54 182.8 0.0 9e-54 182.1 0.0 1.3 1 0 0 1 1 1 1 Velvet factor FAD_binding_7 PF03441.9 EXF86148.1 - 9e-91 303.9 0.8 1.2e-90 303.5 0.6 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.13 EXF86148.1 - 1.3e-34 119.3 0.0 4e-34 117.7 0.0 1.8 2 0 0 2 2 2 1 DNA photolyase ubiquitin PF00240.18 EXF86149.1 - 0.014 14.8 0.0 0.051 12.9 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin family DUF3410 PF11890.3 EXF86149.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) CM2 PF03021.9 EXF86149.1 - 0.11 12.0 0.1 0.4 10.2 0.0 1.9 2 0 0 2 2 2 0 Influenza C virus M2 protein PhyH PF05721.8 EXF86150.1 - 1.2e-31 110.4 0.0 1.6e-31 110.0 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) ABC_membrane PF00664.18 EXF86155.1 - 4.9e-88 295.1 46.7 1.2e-46 159.3 13.3 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EXF86155.1 - 1.2e-66 223.1 0.0 3.2e-32 111.6 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EXF86155.1 - 5.1e-14 52.0 0.0 1.1e-05 24.8 0.0 3.2 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EXF86155.1 - 5.5e-10 39.5 0.1 0.001 19.0 0.0 3.6 3 0 0 3 3 3 2 AAA ATPase domain AAA_21 PF13304.1 EXF86155.1 - 1.6e-09 38.1 1.6 0.075 12.9 0.0 4.6 3 2 0 3 3 2 2 AAA domain AAA_29 PF13555.1 EXF86155.1 - 7.6e-09 34.9 1.1 0.00035 20.0 0.3 3.3 3 0 0 3 3 3 2 P-loop containing region of AAA domain DUF258 PF03193.11 EXF86155.1 - 5.3e-08 32.2 0.0 0.051 12.7 0.0 3.5 3 0 0 3 3 3 2 Protein of unknown function, DUF258 AAA_17 PF13207.1 EXF86155.1 - 1.2e-06 29.3 0.0 0.084 13.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain ABC_ATPase PF09818.4 EXF86155.1 - 1.8e-06 26.8 2.3 0.03 12.9 0.0 3.3 3 0 0 3 3 3 2 Predicted ATPase of the ABC class SbcCD_C PF13558.1 EXF86155.1 - 0.00029 20.6 1.0 1.1 9.2 0.1 3.5 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 EXF86155.1 - 0.00059 19.2 10.0 0.12 11.7 0.0 4.5 6 1 0 6 6 6 2 AAA domain AAA_22 PF13401.1 EXF86155.1 - 0.0015 18.6 2.6 1.6 8.8 0.1 3.6 2 2 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EXF86155.1 - 0.0017 18.2 0.1 2 8.3 0.0 3.7 2 2 2 4 4 4 1 AAA domain AAA_33 PF13671.1 EXF86155.1 - 0.0018 18.1 0.0 3 7.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EXF86155.1 - 0.0024 18.1 0.1 4.2 7.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.1 EXF86155.1 - 0.0055 16.6 0.6 0.7 9.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain DUF87 PF01935.12 EXF86155.1 - 0.0056 16.5 0.2 4.4 7.0 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function DUF87 AAA_5 PF07728.9 EXF86155.1 - 0.0069 16.1 0.1 8.9 6.0 0.0 3.4 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) G-alpha PF00503.15 EXF86155.1 - 0.0092 14.7 0.0 2.7 6.6 0.0 2.6 2 0 0 2 2 2 1 G-protein alpha subunit ATP-synt_ab PF00006.20 EXF86155.1 - 0.01 15.3 0.9 7.5 5.9 0.0 3.5 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 EXF86155.1 - 0.027 14.7 0.5 1.6 8.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain MobB PF03205.9 EXF86155.1 - 0.069 12.8 0.2 14 5.3 0.0 3.1 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EXF86155.1 - 0.072 13.0 0.1 8.4 6.3 0.1 3.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_10 PF12846.2 EXF86155.1 - 0.074 12.4 4.3 15 4.9 0.3 4.2 5 0 0 5 5 5 0 AAA-like domain Fic PF02661.13 EXF86156.1 - 1.3e-13 51.4 0.0 2.7e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 Fic/DOC family DUF1183 PF06682.7 EXF86157.1 - 6.5e-84 282.2 8.5 1e-83 281.6 5.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) BRE1 PF08647.6 EXF86158.1 - 5.3e-21 74.3 8.5 5.3e-21 74.3 5.9 6.4 5 1 1 6 6 6 1 BRE1 E3 ubiquitin ligase Reo_sigmaC PF04582.7 EXF86158.1 - 6.6e-05 22.2 19.3 0.068 12.3 0.5 4.1 4 1 0 5 5 5 3 Reovirus sigma C capsid protein DivIC PF04977.10 EXF86158.1 - 0.0011 18.4 1.8 0.0011 18.4 1.3 10.1 6 3 3 10 10 10 2 Septum formation initiator TPR_MLP1_2 PF07926.7 EXF86158.1 - 0.0047 16.6 9.3 0.0047 16.6 6.5 6.3 3 2 3 6 6 6 1 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 EXF86158.1 - 0.011 15.5 2.1 0.011 15.5 1.4 6.0 6 2 0 6 6 6 0 Protein of unknown function (DUF1664) Seadorna_VP6 PF07407.6 EXF86158.1 - 1.3 7.6 11.9 0.038 12.7 1.3 2.9 2 1 2 4 4 4 0 Seadornavirus VP6 protein Myb_DNA-binding PF00249.26 EXF86159.1 - 3.6e-05 23.7 0.0 6.9e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EXF86159.1 - 0.11 12.6 0.0 0.35 11.0 0.0 2.0 1 1 0 1 1 1 0 Myb-like DNA-binding domain XPC-binding PF09280.6 EXF86160.1 - 1.2e-23 82.3 14.0 2e-23 81.5 9.7 1.4 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.18 EXF86160.1 - 2.1e-19 68.7 0.6 3.3e-19 68.0 0.4 1.3 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.26 EXF86160.1 - 2.3e-17 62.2 5.9 3.3e-09 36.3 0.2 2.9 2 1 0 2 2 2 2 UBA/TS-N domain Rad60-SLD PF11976.3 EXF86160.1 - 3.4e-10 39.4 0.6 6.4e-10 38.5 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like MCM_N PF14551.1 EXF86160.1 - 8.3e-05 23.0 0.0 0.00015 22.2 0.0 1.4 1 0 0 1 1 1 1 MCM N-terminal domain UBA_3 PF09288.5 EXF86160.1 - 0.0022 17.5 0.0 1.1 8.9 0.0 2.4 2 0 0 2 2 2 2 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.1 EXF86160.1 - 0.015 15.1 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EXF86160.1 - 0.015 15.4 0.0 0.036 14.2 0.0 1.7 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain eIF-5a PF01287.15 EXF86160.1 - 0.12 12.3 0.0 0.34 10.8 0.0 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Clathrin_H_link PF13838.1 EXF86160.1 - 1.3 8.9 7.9 0.47 10.3 2.5 2.6 3 0 0 3 3 3 0 Clathrin-H-link DAGK_cat PF00781.19 EXF86162.1 - 8.5e-07 28.4 0.0 1.8e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain TRM PF02005.11 EXF86163.1 - 6.7e-105 351.0 0.0 5.5e-92 308.5 0.0 2.1 2 0 0 2 2 2 2 N2,N2-dimethylguanosine tRNA methyltransferase MTS PF05175.9 EXF86163.1 - 0.026 13.8 0.1 0.079 12.3 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 EXF86163.1 - 0.049 13.6 0.4 0.51 10.3 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain tRNA-synt_1d PF00750.14 EXF86166.1 - 1.1e-47 162.6 0.2 2.1e-47 161.6 0.1 1.4 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EXF86166.1 - 2.6e-13 49.9 0.2 5.1e-13 49.0 0.1 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain Holin_LLH PF09682.5 EXF86168.1 - 0.17 12.0 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Phage holin protein (Holin_LLH) RhodobacterPufX PF11511.3 EXF86168.1 - 0.19 11.1 3.9 0.57 9.6 2.7 1.8 1 0 0 1 1 1 0 Intrinsic membrane protein PufX FAD_binding_4 PF01565.18 EXF86169.1 - 6.9e-18 64.4 4.0 1.3e-17 63.5 2.8 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF86169.1 - 1.6e-11 43.9 0.3 4.2e-11 42.5 0.2 1.8 1 0 0 1 1 1 1 Berberine and berberine like Glyco_hydro_39 PF01229.12 EXF86170.1 - 3e-05 22.6 0.2 4.2e-05 22.1 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Sugar_tr PF00083.19 EXF86171.1 - 1.5e-86 290.8 21.5 1.7e-86 290.6 14.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF86171.1 - 3.3e-20 72.1 31.0 3.3e-20 72.1 21.5 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-C2H2 PF00096.21 EXF86172.1 - 6.4e-10 38.7 9.7 0.00021 21.4 2.7 2.9 2 0 0 2 2 2 2 Zinc finger, C2H2 type Fungal_trans PF04082.13 EXF86172.1 - 6.8e-10 38.2 0.0 1.1e-09 37.5 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-C2H2_4 PF13894.1 EXF86172.1 - 3.7e-09 36.2 6.1 0.00038 20.5 1.3 3.3 2 0 0 2 2 2 2 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EXF86172.1 - 1.3e-07 31.5 11.8 1.3e-06 28.3 2.5 3.0 3 0 0 3 3 3 2 Zinc-finger double domain zf-C2H2_6 PF13912.1 EXF86172.1 - 2.4e-07 30.3 11.0 0.00077 19.2 2.0 3.0 3 0 0 3 3 3 2 C2H2-type zinc finger Zn_clus PF00172.13 EXF86172.1 - 8.6e-06 25.5 12.4 8.6e-06 25.5 8.6 2.0 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain zf-C2H2_jaz PF12171.3 EXF86172.1 - 0.5 10.5 11.3 0.37 10.9 0.8 2.8 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EXF86172.1 - 3.6 7.9 6.3 4.2 7.7 0.2 2.8 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Fungal_trans PF04082.13 EXF86173.1 - 3e-21 75.4 0.0 4.9e-21 74.7 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain ADH_zinc_N PF00107.21 EXF86174.1 - 1.3e-13 50.6 0.0 1.9e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF86174.1 - 0.00019 21.1 0.0 0.00032 20.4 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EXF86174.1 - 0.008 17.0 0.0 0.016 16.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glyco_hydro_61 PF03443.9 EXF86175.1 - 6.4e-62 209.2 0.5 8.9e-62 208.7 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 61 CBM_1 PF00734.13 EXF86175.1 - 5.8e-09 35.4 15.0 1.7e-08 33.9 10.4 1.9 1 0 0 1 1 1 1 Fungal cellulose binding domain LANC_like PF05147.8 EXF86177.1 - 1.4e-22 79.7 0.0 6.5e-22 77.5 0.0 1.8 1 1 0 1 1 1 1 Lanthionine synthetase C-like protein Chitin_bind_3 PF03067.10 EXF86178.1 - 2.8e-07 31.0 0.2 6.8e-07 29.7 0.1 1.6 1 1 0 1 1 1 1 Chitin binding domain DNA_ligase_OB PF03120.11 EXF86178.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent DNA ligase OB-fold domain Acyl-CoA_dh_1 PF00441.19 EXF86179.1 - 7.3e-31 107.3 0.2 1.1e-30 106.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EXF86179.1 - 8.9e-22 76.3 1.0 1.4e-21 75.7 0.7 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EXF86179.1 - 2.3e-11 44.2 0.6 1.1e-09 38.8 0.1 2.7 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EXF86179.1 - 0.0077 16.4 0.1 0.015 15.5 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain CFEM PF05730.6 EXF86180.1 - 9.5e-14 50.9 8.9 1.6e-13 50.2 6.2 1.4 1 0 0 1 1 1 1 CFEM domain Pyr_redox_3 PF13738.1 EXF86181.1 - 2.5e-26 93.0 0.0 3.5e-26 92.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FMO-like PF00743.14 EXF86181.1 - 1.6e-10 39.8 0.0 5.4e-10 38.0 0.0 1.8 2 0 0 2 2 2 1 Flavin-binding monooxygenase-like NAD_binding_8 PF13450.1 EXF86181.1 - 2.8e-09 36.8 0.0 4.6e-08 32.9 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EXF86181.1 - 4.8e-07 29.0 0.0 2.4e-05 23.4 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EXF86181.1 - 8e-07 29.1 0.1 2.7e-05 24.1 0.1 3.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF86181.1 - 1.5e-05 24.0 2.7 0.00025 20.0 0.1 3.3 2 1 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.12 EXF86181.1 - 1.8e-05 23.9 0.0 0.0086 15.1 0.0 2.3 2 0 0 2 2 2 2 Thi4 family Pyr_redox PF00070.22 EXF86181.1 - 0.0001 22.5 0.0 2.6 8.4 0.0 3.4 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EXF86181.1 - 0.0022 17.1 0.0 0.024 13.7 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.19 EXF86181.1 - 0.0041 16.0 0.0 1.8 7.3 0.0 3.0 4 0 0 4 4 4 2 FAD binding domain NAD_binding_9 PF13454.1 EXF86181.1 - 0.0045 16.7 0.9 0.92 9.2 0.0 3.3 4 0 0 4 4 4 1 FAD-NAD(P)-binding Shikimate_DH PF01488.15 EXF86181.1 - 0.02 14.9 0.0 3 7.9 0.0 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Lactamase_B_2 PF12706.2 EXF86182.1 - 5.9e-14 52.0 0.1 8.6e-14 51.5 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EXF86182.1 - 2.8e-08 33.6 0.2 4.4e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Cu_amine_oxid PF01179.15 EXF86184.1 - 2.8e-171 569.8 0.0 3.4e-171 569.5 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain Cu_amine_oxidN3 PF02728.11 EXF86184.1 - 3e-22 78.5 0.1 6.5e-22 77.4 0.1 1.6 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain Cu_amine_oxidN2 PF02727.11 EXF86184.1 - 1.5e-15 56.9 0.0 2.7e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain MFS_1 PF07690.11 EXF86186.1 - 1.9e-35 122.2 30.9 2.7e-35 121.7 21.4 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily OATP PF03137.15 EXF86186.1 - 1.2 7.0 5.7 7.8 4.4 0.3 2.9 1 1 2 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Pex14_N PF04695.8 EXF86187.1 - 0.3 11.1 13.3 1.4 8.9 1.3 3.3 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RTA1 PF04479.8 EXF86188.1 - 1.7e-49 168.3 7.3 2.3e-49 167.9 5.1 1.1 1 0 0 1 1 1 1 RTA1 like protein DUF3176 PF11374.3 EXF86189.1 - 1.3e-32 111.9 2.6 1.2e-31 108.8 0.2 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF3176) Fungal_trans PF04082.13 EXF86190.1 - 2.5e-12 46.2 0.1 4.1e-12 45.5 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain DUF554 PF04474.7 EXF86192.1 - 0.037 13.1 1.3 0.064 12.3 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF554) DUF3341 PF11821.3 EXF86192.1 - 0.11 11.9 0.7 3.1 7.2 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3341) VirB8 PF04335.8 EXF86192.1 - 0.24 10.9 4.5 3.2 7.2 0.0 3.6 4 0 0 4 4 4 0 VirB8 protein DUF4134 PF13572.1 EXF86192.1 - 0.25 11.5 0.2 0.25 11.5 0.1 3.4 3 2 0 3 3 3 0 Domain of unknown function (DUF4134) DUF1129 PF06570.6 EXF86192.1 - 7.2 5.8 13.2 2.2 7.5 0.4 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) 4HBT PF03061.17 EXF86193.1 - 7.8e-14 51.5 0.0 1.1e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EXF86193.1 - 0.0011 18.7 0.0 0.0011 18.7 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily DUF4442 PF14539.1 EXF86193.1 - 0.0058 16.6 0.0 0.0077 16.2 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4442) Tfb2 PF03849.9 EXF86194.1 - 4.4e-133 443.4 0.0 5.3e-133 443.1 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EXF86194.1 - 1.9e-06 27.6 0.0 4.7e-06 26.3 0.0 1.8 1 1 0 1 1 1 1 Helicase conserved C-terminal domain SinI PF08671.5 EXF86194.1 - 0.095 12.1 0.1 4.2 6.8 0.0 2.6 2 0 0 2 2 2 0 Anti-repressor SinI NRDE PF05742.7 EXF86196.1 - 2.8e-43 148.2 0.0 5e-43 147.3 0.0 1.3 1 1 0 1 1 1 1 NRDE protein ABC_tran PF00005.22 EXF86197.1 - 3.6e-39 134.1 0.0 4e-18 66.0 0.0 2.7 3 0 0 3 3 2 2 ABC transporter ABC_membrane PF00664.18 EXF86197.1 - 6.7e-24 84.7 46.1 1e-21 77.6 10.4 3.3 3 0 0 3 3 3 2 ABC transporter transmembrane region AAA_21 PF13304.1 EXF86197.1 - 2.6e-13 50.5 0.1 0.0027 17.7 0.0 4.1 2 2 1 3 3 3 3 AAA domain SMC_N PF02463.14 EXF86197.1 - 5e-08 32.4 0.3 0.0046 16.2 0.0 3.9 2 2 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EXF86197.1 - 1.7e-06 27.4 0.1 0.037 13.5 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.1 EXF86197.1 - 2.4e-05 24.4 0.0 0.051 13.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EXF86197.1 - 2.6e-05 23.4 0.0 0.12 11.5 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EXF86197.1 - 0.00035 20.0 0.4 0.84 8.9 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EXF86197.1 - 0.00039 20.4 1.0 0.41 10.6 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EXF86197.1 - 0.00048 20.9 0.0 0.43 11.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EXF86197.1 - 0.0009 19.1 0.0 0.33 10.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EXF86197.1 - 0.001 18.0 0.0 0.087 11.7 0.0 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.1 EXF86197.1 - 0.0018 18.5 0.0 1.7 8.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EXF86197.1 - 0.0027 17.3 0.2 1.3 8.7 0.0 2.5 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EXF86197.1 - 0.0035 17.2 0.1 1.2 9.1 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA PF00004.24 EXF86197.1 - 0.0037 17.4 0.0 1.9 8.6 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EXF86197.1 - 0.008 16.6 0.0 0.15 12.5 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein Dynamin_N PF00350.18 EXF86197.1 - 0.012 15.4 0.1 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Dynamin family AAA_23 PF13476.1 EXF86197.1 - 0.014 15.7 0.0 4.8 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EXF86197.1 - 0.036 13.5 0.1 5.7 6.2 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain Zeta_toxin PF06414.7 EXF86197.1 - 0.052 12.6 0.0 7.1 5.6 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.12 EXF86197.1 - 0.2 11.4 0.1 0.89 9.3 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF87 PfkB PF00294.19 EXF86198.1 - 6.3e-08 32.1 0.0 7.9e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Peptidase_S8 PF00082.17 EXF86199.1 - 1e-44 152.8 6.1 1.6e-44 152.1 4.3 1.3 1 0 0 1 1 1 1 Subtilase family PA PF02225.17 EXF86199.1 - 5.2e-10 38.9 0.0 1.3e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 PA domain DUF1034 PF06280.7 EXF86199.1 - 3.4e-07 30.6 1.6 4.8e-06 26.9 0.1 2.5 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) Pap_E4 PF02711.9 EXF86200.1 - 0.14 12.9 0.9 0.31 11.8 0.6 1.5 1 0 0 1 1 1 0 E4 protein Fungal_trans_2 PF11951.3 EXF86202.1 - 1.2e-09 37.3 0.1 1.6e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain T2SJ PF11612.3 EXF86202.1 - 0.085 12.5 0.0 2.2 7.9 0.0 2.6 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein J CVNH PF08881.5 EXF86203.1 - 1.7e-09 37.8 0.0 3.1e-09 37.0 0.0 1.5 2 0 0 2 2 2 1 CVNH domain DUF1385 PF07136.6 EXF86204.1 - 0.1 11.6 2.2 0.4 9.7 1.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1385) FAD_binding_3 PF01494.14 EXF86205.1 - 5.3e-22 78.3 0.0 1e-21 77.4 0.0 1.5 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF86205.1 - 1.1e-10 40.9 0.8 1.3e-06 27.6 0.4 2.2 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF86205.1 - 7.7e-06 25.8 0.0 1.8e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EXF86205.1 - 5.4e-05 22.4 0.0 0.065 12.2 0.0 2.2 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.9 EXF86205.1 - 7.1e-05 22.7 0.9 0.0011 18.8 0.6 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EXF86205.1 - 0.00099 19.4 0.4 0.0086 16.4 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF86205.1 - 0.0011 18.0 1.7 0.11 11.3 0.0 2.6 3 0 0 3 3 3 2 Lycopene cyclase protein GIDA PF01134.17 EXF86205.1 - 0.0012 17.7 0.0 0.0017 17.3 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.9 EXF86205.1 - 0.0046 15.6 0.4 0.12 10.9 0.1 2.1 2 0 0 2 2 2 1 Tryptophan halogenase AlaDh_PNT_C PF01262.16 EXF86205.1 - 0.008 15.7 0.1 0.014 14.9 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain SE PF08491.5 EXF86205.1 - 0.0098 14.7 0.0 2.8 6.7 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase NAD_binding_9 PF13454.1 EXF86205.1 - 0.012 15.3 0.9 0.55 9.9 0.1 3.0 3 0 0 3 3 3 0 FAD-NAD(P)-binding FAD_binding_2 PF00890.19 EXF86205.1 - 0.016 14.0 0.7 0.023 13.5 0.5 1.2 1 0 0 1 1 1 0 FAD binding domain TrkA_N PF02254.13 EXF86205.1 - 0.018 15.0 0.1 0.06 13.3 0.0 1.8 1 1 0 1 1 1 0 TrkA-N domain HI0933_like PF03486.9 EXF86205.1 - 0.018 13.5 0.1 0.035 12.5 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein NAD_Gly3P_dh_N PF01210.18 EXF86205.1 - 0.031 14.0 0.1 0.077 12.7 0.0 1.6 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Fungal_trans PF04082.13 EXF86206.1 - 2.8e-08 32.9 0.3 4.7e-08 32.2 0.2 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Rota_NSP3 PF01665.11 EXF86206.1 - 0.058 12.3 0.0 0.16 10.8 0.0 1.6 1 1 1 2 2 2 0 Rotavirus non-structural protein NSP3 adh_short PF00106.20 EXF86207.1 - 2.2e-29 102.5 0.2 2.9e-29 102.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF86207.1 - 1.6e-20 73.8 0.0 1.9e-20 73.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF86207.1 - 4.3e-07 29.7 0.1 6.6e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EXF86207.1 - 0.00023 20.7 0.0 0.00044 19.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EXF86207.1 - 0.0026 17.5 0.1 0.0058 16.4 0.1 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF1776 PF08643.5 EXF86207.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Beta-lactamase PF00144.19 EXF86208.1 - 1.8e-45 155.3 0.0 2.4e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EXF86208.1 - 0.11 11.6 0.0 2.8 7.1 0.0 2.1 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase ICL PF00463.16 EXF86208.1 - 0.2 9.8 0.0 0.3 9.2 0.0 1.1 1 0 0 1 1 1 0 Isocitrate lyase family DUF3425 PF11905.3 EXF86209.1 - 1.1e-33 115.9 1.0 1.1e-33 115.9 0.7 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) DUF1653 PF07866.6 EXF86209.1 - 0.11 12.6 0.7 25 5.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1653) bZIP_1 PF00170.16 EXF86209.1 - 1.3 9.0 10.0 2.3 8.2 7.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor Zn_clus PF00172.13 EXF86210.1 - 9.8e-07 28.5 8.9 1.9e-06 27.6 6.2 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF86210.1 - 2.8e-06 26.1 0.2 4.6e-06 25.4 0.1 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Lipase_GDSL_2 PF13472.1 EXF86211.1 - 7.2e-07 29.4 0.0 1.4e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family RRM_1 PF00076.17 EXF86212.1 - 1.5e-15 56.5 0.0 1.3e-09 37.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF86212.1 - 4.3e-12 45.8 0.0 7.4e-07 29.0 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF86212.1 - 3.1e-10 39.7 0.0 0.00058 19.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) YhzD PF14120.1 EXF86212.1 - 0.21 11.5 0.4 7.3 6.5 0.1 2.5 2 0 0 2 2 2 0 YhzD-like protein YlaH PF14036.1 EXF86213.1 - 0.022 14.8 6.1 0.022 14.8 4.2 2.5 3 0 0 3 3 3 0 YlaH-like protein Serpentine_r_xa PF03383.10 EXF86213.1 - 1.2 8.9 10.7 0.21 11.3 4.2 2.1 1 1 1 2 2 2 0 Caenorhabditis serpentine receptor-like protein, class xa Abhydrolase_6 PF12697.2 EXF86214.1 - 1.4e-28 100.3 0.0 2e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF86214.1 - 1.1e-10 41.4 0.2 2.4e-10 40.3 0.1 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EXF86214.1 - 0.00053 19.2 0.1 2.3 7.4 0.0 3.6 3 1 1 4 4 4 2 Prolyl oligopeptidase family FSH1 PF03959.8 EXF86214.1 - 0.02 14.3 0.0 0.045 13.1 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 EXF86214.1 - 0.052 13.0 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold AATase PF07247.7 EXF86215.1 - 1.5e-13 50.1 0.0 9.1e-13 47.5 0.0 2.1 1 1 0 1 1 1 1 Alcohol acetyltransferase Methyltransf_2 PF00891.13 EXF86216.1 - 9.5e-33 113.3 0.0 1.6e-32 112.6 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase Pribosyltran PF00156.22 EXF86217.1 - 5.5e-10 39.0 0.3 3.6e-09 36.4 0.2 2.0 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Oxidored-like PF09791.4 EXF86219.1 - 6.8e-25 86.2 2.8 6.8e-25 86.2 1.9 2.3 2 0 0 2 2 2 1 Oxidoreductase-like protein, N-terminal Trypan_PARP PF05887.6 EXF86219.1 - 9.3 6.0 16.5 1.4 8.7 8.7 1.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) SYF2 PF08231.7 EXF86220.1 - 0.021 14.9 1.0 0.059 13.5 0.7 1.7 1 0 0 1 1 1 0 SYF2 splicing factor BsuPI PF12690.2 EXF86222.1 - 0.063 13.0 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Intracellular proteinase inhibitor Tyrosinase PF00264.15 EXF86224.1 - 1.6e-20 74.2 2.0 2.8e-20 73.4 1.4 1.3 1 0 0 1 1 1 1 Common central domain of tyrosinase FAD_binding_4 PF01565.18 EXF86224.1 - 2.4e-17 62.6 1.5 9.7e-17 60.7 1.3 1.8 2 0 0 2 2 2 1 FAD binding domain P-mevalo_kinase PF04275.9 EXF86224.1 - 5.8e-10 38.8 0.0 1.2e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Phosphomevalonate kinase Pribosyltran PF00156.22 EXF86224.1 - 0.00011 21.9 0.0 0.00031 20.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain SUN PF03856.8 EXF86225.1 - 0.13 11.5 0.0 0.16 11.2 0.0 1.1 1 0 0 1 1 1 0 Beta-glucosidase (SUN family) Gly_transf_sug PF04488.10 EXF86226.1 - 2.2e-07 31.1 0.0 5.2e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Gypsy PF07253.6 EXF86227.1 - 0.025 12.9 0.2 0.038 12.3 0.1 1.2 1 0 0 1 1 1 0 Gypsy protein RF-1 PF00472.15 EXF86227.1 - 0.052 13.3 0.4 0.16 11.8 0.3 1.7 1 0 0 1 1 1 0 RF-1 domain Pkinase PF00069.20 EXF86228.1 - 0.0023 17.1 0.0 0.0031 16.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF86228.1 - 0.026 13.5 0.0 0.043 12.8 0.0 1.4 1 1 0 1 1 1 0 Protein tyrosine kinase OTT_1508_deam PF14441.1 EXF86229.1 - 1e-08 35.1 0.0 1.5e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 OTT_1508-like deaminase NB-ARC PF00931.17 EXF86232.1 - 5.6e-09 35.2 0.0 1e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain AAA_22 PF13401.1 EXF86232.1 - 3.6e-06 27.1 0.0 9.4e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF676 PF05057.9 EXF86232.1 - 1.7e-05 24.2 0.1 4.7e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.2 EXF86232.1 - 4.5e-05 23.4 0.6 9.1e-05 22.4 0.4 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EXF86232.1 - 0.0013 18.3 0.2 0.0026 17.3 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein IstB_IS21 PF01695.12 EXF86232.1 - 0.016 14.6 0.0 0.042 13.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Abhydrolase_5 PF12695.2 EXF86232.1 - 0.033 13.9 0.1 0.068 12.9 0.1 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family SRP54 PF00448.17 EXF86232.1 - 0.036 13.5 0.1 0.087 12.2 0.0 1.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_16 PF13191.1 EXF86232.1 - 0.037 14.0 0.2 0.15 12.0 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain Replic_Relax PF13814.1 EXF86232.1 - 0.062 13.1 0.7 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 Replication-relaxation DNA_pol_A_exo1 PF01612.15 EXF86234.1 - 1.4e-12 47.4 0.0 3.4e-12 46.1 0.0 1.6 1 1 0 1 1 1 1 3'-5' exonuclease HET PF06985.6 EXF86235.1 - 2.3e-31 108.8 2.6 6.8e-31 107.2 1.8 1.9 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) NdhO PF11910.3 EXF86235.1 - 0.091 12.4 1.9 8.6 6.0 0.1 3.2 2 0 0 2 2 2 0 Cyanobacterial and plant NDH-1 subunit O DUF3217 PF11506.3 EXF86235.1 - 0.15 11.7 3.5 16 5.2 0.0 4.4 1 1 4 5 5 5 0 Protein of unknown function (DUF3217) Drf_DAD PF06345.6 EXF86235.1 - 0.15 11.9 0.8 0.42 10.4 0.1 2.2 2 0 0 2 2 2 0 DRF Autoregulatory Domain Dynamin_N PF00350.18 EXF86236.1 - 1.1e-31 109.8 0.1 2.1e-31 109.0 0.1 1.5 1 0 0 1 1 1 1 Dynamin family Dynamin_M PF01031.15 EXF86236.1 - 2.6e-17 62.5 0.0 4.4e-17 61.7 0.0 1.3 1 0 0 1 1 1 1 Dynamin central region MMR_HSR1 PF01926.18 EXF86236.1 - 1.6e-05 24.8 0.1 0.00094 19.1 0.0 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EXF86236.1 - 0.016 15.6 0.0 0.061 13.8 0.0 2.0 2 0 0 2 2 2 0 Miro-like protein FeoB_N PF02421.13 EXF86236.1 - 0.018 14.3 0.0 3.8 6.7 0.0 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B ABC_tran PF00005.22 EXF86236.1 - 0.096 12.9 0.0 0.23 11.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter GED PF02212.13 EXF86236.1 - 0.27 11.1 2.6 2.1 8.2 1.8 2.5 1 1 0 1 1 1 0 Dynamin GTPase effector domain RdRP PF05183.7 EXF86237.1 - 8.8e-113 377.9 0.1 1.3e-112 377.3 0.0 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase DUF2301 PF10063.4 EXF86237.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized integral membrane protein (DUF2301) Piwi PF02171.12 EXF86238.1 - 2.9e-52 177.5 0.0 1.8e-51 174.9 0.0 2.0 1 1 0 1 1 1 1 Piwi domain PAZ PF02170.17 EXF86238.1 - 0.066 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 PAZ domain Pkinase PF00069.20 EXF86240.1 - 7.6e-41 139.9 0.0 2.5e-40 138.2 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF86240.1 - 6.6e-25 87.6 0.0 8.7e-25 87.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF86240.1 - 0.00076 18.5 0.0 0.072 12.0 0.0 2.2 2 0 0 2 2 2 2 Kinase-like FHA PF00498.21 EXF86240.1 - 0.086 12.9 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 FHA domain PNP_UDP_1 PF01048.15 EXF86241.1 - 2.4e-12 46.3 0.0 1.1e-11 44.1 0.0 2.1 1 1 0 1 1 1 1 Phosphorylase superfamily NACHT PF05729.7 EXF86241.1 - 1.7e-10 40.8 0.1 3.4e-10 39.8 0.1 1.5 1 0 0 1 1 1 1 NACHT domain NB-ARC PF00931.17 EXF86241.1 - 7.1e-07 28.3 0.0 1.5e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EXF86241.1 - 4.9e-06 26.6 2.1 1.3e-05 25.2 0.1 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EXF86241.1 - 1.1e-05 25.6 0.1 4e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain Arch_ATPase PF01637.13 EXF86241.1 - 3.7e-05 23.5 0.0 6.8e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 EXF86241.1 - 0.011 15.6 0.0 0.17 11.7 0.0 2.6 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EXF86241.1 - 0.039 14.1 0.0 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 RNA helicase KAP_NTPase PF07693.9 EXF86241.1 - 0.064 12.2 0.3 1.5 7.7 0.0 2.2 1 1 1 2 2 2 0 KAP family P-loop domain Parvo_NS1 PF01057.12 EXF86241.1 - 0.13 11.1 0.0 0.22 10.3 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 OTT_1508_deam PF14441.1 EXF86247.1 - 2.1e-13 50.2 0.0 2.6e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 OTT_1508-like deaminase Methyltransf_23 PF13489.1 EXF86248.1 - 2.4e-07 30.6 0.0 4.1e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EXF86248.1 - 0.02 14.4 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Arg_repressor PF01316.16 EXF86248.1 - 0.076 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Arginine repressor, DNA binding domain DUF445 PF04286.7 EXF86250.1 - 0.0016 18.0 2.9 0.0025 17.4 2.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF445) NPV_P10 PF05531.7 EXF86250.1 - 0.011 15.9 1.2 0.074 13.3 1.0 2.4 2 1 0 2 2 1 0 Nucleopolyhedrovirus P10 protein IncA PF04156.9 EXF86250.1 - 0.019 14.5 9.1 0.032 13.8 6.3 1.3 1 0 0 1 1 1 0 IncA protein Tropomyosin_1 PF12718.2 EXF86250.1 - 0.021 14.6 8.5 0.038 13.8 5.9 1.4 1 0 0 1 1 1 0 Tropomyosin like DUF3573 PF12097.3 EXF86250.1 - 0.029 13.0 2.3 0.043 12.4 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) ATG16 PF08614.6 EXF86250.1 - 0.036 13.8 10.3 0.059 13.1 7.1 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF724 PF05266.9 EXF86250.1 - 0.14 11.7 5.6 0.22 11.1 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) APG6 PF04111.7 EXF86250.1 - 0.25 10.3 6.2 0.39 9.7 4.3 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EXF86250.1 - 0.32 8.8 1.5 0.37 8.5 1.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF904 PF06005.7 EXF86250.1 - 0.35 11.1 15.6 0.14 12.4 4.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF904) bZIP_1 PF00170.16 EXF86250.1 - 0.47 10.4 6.6 0.14 12.0 2.0 1.9 2 0 0 2 2 2 0 bZIP transcription factor DUF4327 PF14217.1 EXF86250.1 - 0.47 10.2 3.6 0.47 10.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4327) DUF972 PF06156.8 EXF86250.1 - 2.2 8.6 10.7 24 5.3 6.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DivIC PF04977.10 EXF86250.1 - 3.3 7.2 10.4 20 4.7 7.2 2.2 1 1 0 1 1 1 0 Septum formation initiator eIF-4B PF06273.6 EXF86250.1 - 5.6 5.5 6.6 9.6 4.8 4.6 1.3 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B AA_permease PF00324.16 EXF86251.1 - 0.088 11.1 0.1 0.11 10.8 0.0 1.1 1 0 0 1 1 1 0 Amino acid permease Pkinase PF00069.20 EXF86254.1 - 7.7e-05 21.9 0.0 0.00013 21.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EXF86254.1 - 0.0054 16.5 0.1 0.17 11.5 0.0 2.8 2 1 1 3 3 3 1 Phosphotransferase enzyme family dsrm PF00035.20 EXF86256.1 - 0.0018 18.7 0.0 0.0029 18.1 0.0 1.3 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 EXF86256.1 - 0.0019 18.4 0.1 0.0068 16.6 0.0 1.8 1 1 0 1 1 1 1 double strand RNA binding domain from DEAD END PROTEIN 1 BCS1_N PF08740.6 EXF86258.1 - 2.3e-20 73.0 0.0 4.5e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EXF86258.1 - 1.1e-15 57.9 0.0 2.5e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EXF86258.1 - 1.1e-05 25.4 1.2 0.00021 21.3 0.2 3.1 2 1 1 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 EXF86258.1 - 0.0002 21.2 0.0 0.00057 19.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EXF86258.1 - 0.00029 21.6 0.0 0.00072 20.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EXF86258.1 - 0.0038 16.3 0.0 0.0073 15.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EXF86258.1 - 0.0063 16.1 0.0 0.0089 15.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EXF86258.1 - 0.0073 16.4 0.0 0.035 14.2 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EXF86258.1 - 0.015 14.6 0.0 0.031 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EXF86258.1 - 0.029 14.6 0.0 0.071 13.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EXF86258.1 - 0.062 13.2 0.1 1.9 8.4 0.0 2.5 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.17 EXF86258.1 - 0.066 13.3 0.0 0.18 11.9 0.0 1.8 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.12 EXF86258.1 - 0.092 12.1 0.0 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 EXF86258.1 - 0.099 12.4 0.0 0.29 10.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain FAD_binding_4 PF01565.18 EXF86259.1 - 7.2e-27 93.5 0.4 1.3e-26 92.7 0.3 1.4 1 0 0 1 1 1 1 FAD binding domain DUF3435 PF11917.3 EXF86264.1 - 7.7e-63 212.6 1.4 9e-63 212.4 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3435) Kdo PF06293.9 EXF86265.1 - 0.0015 17.6 0.0 0.0033 16.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EXF86265.1 - 0.0021 17.8 7.2 0.0046 16.7 0.0 3.5 3 1 1 4 4 4 1 Phosphotransferase enzyme family HSDR_N_2 PF13588.1 EXF86265.1 - 0.003 17.3 0.0 0.77 9.5 0.0 2.4 2 0 0 2 2 2 2 Type I restriction enzyme R protein N terminus (HSDR_N) Radial_spoke_3 PF06098.6 EXF86265.1 - 0.014 14.4 7.6 0.031 13.3 5.3 1.6 1 0 0 1 1 1 0 Radial spoke protein 3 CAF-1_p150 PF11600.3 EXF86265.1 - 0.31 10.3 16.7 0.66 9.3 11.6 1.5 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Atrophin-1 PF03154.10 EXF86265.1 - 1.3 7.0 8.6 2.1 6.4 6.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family Mnd1 PF03962.10 EXF86265.1 - 4 7.0 7.7 8.8 5.9 5.3 1.6 1 0 0 1 1 1 0 Mnd1 family RCR PF12273.3 EXF86269.1 - 6.2e-09 36.4 2.2 9.4e-09 35.9 1.5 1.3 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red MAD PF05557.8 EXF86270.1 - 0.042 11.9 2.0 0.08 11.0 1.4 1.4 1 0 0 1 1 1 0 Mitotic checkpoint protein CPSF73-100_C PF11718.3 EXF86270.1 - 0.083 12.2 0.6 0.1 11.9 0.4 1.2 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term tRNA-synt_2c PF01411.14 EXF86271.1 - 2.6e-208 692.8 0.0 4.3e-208 692.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EXF86271.1 - 6.1e-17 61.2 0.3 1.8e-16 59.7 0.2 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EXF86271.1 - 0.0001 21.9 0.5 0.00035 20.2 0.4 2.0 1 0 0 1 1 1 1 DHHA1 domain Methyltransf_28 PF02636.12 EXF86272.1 - 1.7e-40 139.0 0.0 2.6e-40 138.4 0.0 1.3 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PRMT5 PF05185.11 EXF86272.1 - 0.0097 14.8 0.0 0.016 14.1 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PHP_C PF13263.1 EXF86272.1 - 0.08 12.4 0.0 0.36 10.3 0.0 1.9 2 0 0 2 2 2 0 PHP-associated PALP PF00291.20 EXF86273.1 - 4.2e-56 190.4 3.9 5.6e-56 189.9 2.7 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme TFIIS_M PF07500.9 EXF86274.1 - 1.9e-29 102.0 2.0 4e-29 101.0 1.4 1.6 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EXF86274.1 - 1.4e-18 66.1 5.9 2.3e-18 65.5 4.1 1.4 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EXF86274.1 - 1.6e-14 53.1 0.2 3.3e-14 52.0 0.1 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain DUF3526 PF12040.3 EXF86274.1 - 0.031 14.4 0.5 0.3 11.2 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3526) Hus1 PF04005.7 EXF86274.1 - 0.032 13.1 0.9 0.049 12.5 0.6 1.2 1 0 0 1 1 1 0 Hus1-like protein DUF3713 PF12506.3 EXF86274.1 - 0.095 12.7 0.9 1.1 9.3 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) zf-RING_2 PF13639.1 EXF86276.1 - 1.5e-12 47.1 6.1 2.9e-12 46.2 4.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EXF86276.1 - 6.8e-07 29.2 6.4 1.3e-06 28.3 4.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EXF86276.1 - 1e-06 28.2 5.3 1.9e-06 27.4 3.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EXF86276.1 - 5.8e-06 25.9 4.5 1e-05 25.1 3.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EXF86276.1 - 8.5e-06 25.7 1.5 2e-05 24.6 1.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EXF86276.1 - 9.8e-06 25.1 3.5 1.8e-05 24.3 2.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EXF86276.1 - 0.0071 16.1 1.0 0.016 15.0 0.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EXF86276.1 - 0.017 14.7 0.9 0.017 14.7 0.6 2.4 2 0 0 2 2 2 0 RING-type zinc-finger GP41 PF00517.12 EXF86276.1 - 0.025 14.1 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Retroviral envelope protein zf-RING_4 PF14570.1 EXF86276.1 - 0.033 13.7 3.0 0.057 13.0 2.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Cucumo_2B PF03263.8 EXF86276.1 - 0.065 13.5 0.1 0.37 11.0 0.1 2.2 2 0 0 2 2 2 0 Cucumovirus protein 2B RINGv PF12906.2 EXF86276.1 - 0.1 12.6 2.8 0.18 11.8 1.9 1.4 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.1 EXF86276.1 - 0.82 9.5 5.9 1.9 8.4 4.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING PHD PF00628.24 EXF86276.1 - 1.1 9.0 3.7 2.2 8.0 2.6 1.6 1 0 0 1 1 1 0 PHD-finger Vps39_2 PF10367.4 EXF86276.1 - 1.8 8.8 4.3 0.62 10.2 0.4 2.1 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 Glyco_hydro_45 PF02015.11 EXF86277.1 - 6.6e-30 104.6 1.6 7.7e-30 104.4 1.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 45 Inositol_P PF00459.20 EXF86278.1 - 6.1e-67 225.7 0.0 7.2e-67 225.5 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family DUF331 PF03889.8 EXF86278.1 - 0.12 11.6 0.5 0.23 10.7 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function Isochorismatase PF00857.15 EXF86280.1 - 2.7e-33 115.3 0.0 8.5e-32 110.4 0.0 2.0 1 1 0 1 1 1 1 Isochorismatase family XhoI PF04555.8 EXF86280.1 - 0.079 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Restriction endonuclease XhoI Lactamase_B_2 PF12706.2 EXF86281.1 - 1.1e-26 93.5 0.0 1.4e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EXF86281.1 - 1.1e-12 47.9 0.0 1.6e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain ApoLp-III PF07464.6 EXF86282.1 - 0.11 12.5 0.1 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) RasGEF PF00617.14 EXF86284.1 - 1.5e-62 210.6 0.0 2.5e-62 209.9 0.0 1.3 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EXF86284.1 - 4.9e-27 94.0 0.7 1.1e-26 92.9 0.5 1.6 1 0 0 1 1 1 1 RasGEF N-terminal motif SH3_1 PF00018.23 EXF86284.1 - 7.3e-16 57.3 0.1 1.5e-15 56.3 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EXF86284.1 - 2.3e-14 52.7 0.2 4.8e-14 51.6 0.2 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EXF86284.1 - 2.5e-13 49.2 0.1 5.3e-13 48.2 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain WW PF00397.21 EXF86284.1 - 0.065 13.1 0.0 0.15 11.9 0.0 1.6 1 0 0 1 1 1 0 WW domain Fungal_trans PF04082.13 EXF86286.1 - 3.2e-17 62.2 2.1 5.3e-17 61.5 1.5 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EXF86286.1 - 2.4e-08 33.8 12.2 1.7e-05 24.8 4.1 3.0 2 0 0 2 2 2 2 Zinc-finger double domain zf-C2H2_4 PF13894.1 EXF86286.1 - 4.8e-05 23.4 13.0 0.0041 17.3 3.6 3.2 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.21 EXF86286.1 - 0.00021 21.4 14.7 0.035 14.4 4.0 3.0 2 0 0 2 2 2 2 Zinc finger, C2H2 type Glyco_hydro_16 PF00722.16 EXF86287.1 - 2.4e-18 66.0 0.0 3.6e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Fungal_trans_2 PF11951.3 EXF86289.1 - 3.1e-12 45.7 0.3 4.4e-09 35.4 0.0 2.2 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF86289.1 - 2e-07 30.8 11.7 3.6e-07 29.9 8.1 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain DUF4619 PF15398.1 EXF86289.1 - 0.081 12.3 0.4 0.13 11.6 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) Pro_isomerase PF00160.16 EXF86290.1 - 3.2e-47 160.6 0.0 6.1e-47 159.7 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.10 EXF86290.1 - 0.00016 21.5 0.0 0.00059 19.7 0.0 1.9 1 0 0 1 1 1 1 U-box domain Lung_7-TM_R PF06814.8 EXF86291.1 - 2.1e-71 240.2 16.8 2.7e-71 239.9 11.6 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor PrgI PF12666.2 EXF86291.1 - 0.24 11.5 22.3 0.33 11.1 2.6 3.6 1 1 1 3 3 3 0 PrgI family protein DUF4492 PF14899.1 EXF86291.1 - 0.38 10.2 5.7 0.1 12.1 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) Methyltransf_28 PF02636.12 EXF86292.1 - 1.9e-78 263.3 0.0 2.4e-78 263.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Pkinase PF00069.20 EXF86293.1 - 2e-61 207.4 0.0 2.7e-61 207.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF86293.1 - 3.5e-29 101.6 0.0 5.9e-29 100.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF86293.1 - 0.00026 20.0 0.0 0.00046 19.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EXF86293.1 - 0.045 13.4 2.1 0.064 12.9 0.0 2.2 2 1 1 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.9 EXF86293.1 - 0.063 12.3 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rtf2 PF04641.7 EXF86293.1 - 6.7 5.8 12.0 8.2 5.5 7.6 1.5 2 0 0 2 2 2 0 Rtf2 RING-finger DmpG_comm PF07836.6 EXF86294.1 - 0.13 11.6 0.0 0.3 10.5 0.0 1.5 1 0 0 1 1 1 0 DmpG-like communication domain Rdx PF10262.4 EXF86295.1 - 1.8e-18 66.3 0.0 3.2e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Rdx family DUF572 PF04502.8 EXF86295.1 - 0.9 8.7 5.1 1.3 8.1 3.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Metallophos PF00149.23 EXF86296.1 - 1.4e-44 151.8 0.2 1.7e-44 151.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-HC5HC2H_2 PF13832.1 EXF86297.1 - 4.8e-34 116.6 7.9 4.8e-34 116.6 5.5 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.1 EXF86297.1 - 4.4e-27 94.0 7.6 4.4e-27 94.0 5.2 2.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain EPL1 PF10513.4 EXF86297.1 - 2.7e-18 66.7 0.4 1.1e-17 64.7 0.1 2.3 2 0 0 2 2 2 1 Enhancer of polycomb-like PHD_2 PF13831.1 EXF86297.1 - 2.9e-14 52.0 2.1 2.9e-14 52.0 1.4 2.5 2 0 0 2 2 2 1 PHD-finger PHD PF00628.24 EXF86297.1 - 3.1e-09 36.3 23.4 8.9e-08 31.7 6.7 2.7 2 0 0 2 2 2 2 PHD-finger zf-RING-like PF08746.6 EXF86297.1 - 0.011 15.6 6.0 0.011 15.6 4.2 2.8 2 0 0 2 2 2 0 RING-like domain Biotin_lipoyl PF00364.17 EXF86298.1 - 1.2e-18 66.5 1.0 2.3e-18 65.5 0.7 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EXF86298.1 - 2.7e-06 26.9 0.0 2.7e-06 26.9 0.0 2.4 3 0 0 3 3 3 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EXF86298.1 - 4.7e-05 22.9 0.1 0.00026 20.5 0.0 2.3 2 0 0 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.1 EXF86298.1 - 0.056 13.7 0.1 1.1 9.6 0.0 2.5 1 1 1 2 2 2 0 HlyD family secretion protein QRPTase_N PF02749.11 EXF86298.1 - 0.13 12.0 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, N-terminal domain HlyD_2 PF12700.2 EXF86298.1 - 0.15 11.1 0.1 8.9 5.3 0.0 2.1 1 1 1 2 2 2 0 HlyD family secretion protein PEGSRP PF07623.6 EXF86300.1 - 2 7.7 5.3 0.29 10.4 0.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1584) LRR_4 PF12799.2 EXF86301.1 - 1.6e-16 59.4 3.3 4.9e-06 26.0 1.6 4.7 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EXF86301.1 - 3.8e-13 48.9 3.9 9.9e-09 34.8 1.9 2.7 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.28 EXF86301.1 - 1.2e-09 36.8 6.3 0.28 11.3 0.2 6.4 5 1 1 6 6 6 3 Leucine Rich Repeat LRR_7 PF13504.1 EXF86301.1 - 0.00029 20.5 7.8 26 5.6 0.0 5.6 5 0 0 5 5 5 2 Leucine rich repeat LRR_6 PF13516.1 EXF86301.1 - 0.00042 20.0 5.8 30 5.1 0.1 5.8 6 0 0 6 6 6 0 Leucine Rich repeat Fungal_trans PF04082.13 EXF86302.1 - 1.3e-22 79.9 0.0 2.3e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF86302.1 - 1.2e-08 34.7 12.3 2.2e-08 33.8 8.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Glyco_hydro_88 PF07470.8 EXF86304.1 - 5.2e-32 111.1 0.2 5.9e-32 111.0 0.1 1.1 1 0 0 1 1 1 1 Glycosyl Hydrolase Family 88 p450 PF00067.17 EXF86306.1 - 2e-57 194.7 0.0 3.6e-57 193.9 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 ketoacyl-synt PF00109.21 EXF86307.1 - 2.3e-62 210.7 0.2 5.3e-62 209.5 0.1 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EXF86307.1 - 5.8e-49 167.1 0.0 1.1e-48 166.1 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EXF86307.1 - 8.7e-36 122.3 0.9 2.2e-35 121.0 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EXF86307.1 - 9.8e-16 57.7 0.0 1.7e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Polyketide synthase dehydratase PP-binding PF00550.20 EXF86307.1 - 2.5e-13 50.0 0.2 7.4e-13 48.5 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thioesterase PF00975.15 EXF86307.1 - 4.9e-11 43.2 0.0 2e-10 41.3 0.0 2.1 2 0 0 2 2 2 1 Thioesterase domain Abhydrolase_6 PF12697.2 EXF86307.1 - 0.0048 16.8 2.0 2.3 8.0 0.0 3.1 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF86307.1 - 0.0051 16.5 0.1 0.11 12.2 0.0 2.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family adh_short PF00106.20 EXF86308.1 - 9e-16 58.2 0.1 1.4e-15 57.6 0.1 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF86308.1 - 5.9e-07 29.4 0.0 7.7e-07 29.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF86308.1 - 4.2e-05 23.2 0.1 7.3e-05 22.5 0.1 1.3 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 EXF86308.1 - 0.02 14.0 0.0 0.026 13.6 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) THF_DHG_CYH_C PF02882.14 EXF86308.1 - 0.062 12.3 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain UPF0506 PF11703.3 EXF86308.1 - 0.069 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 UPF0506 p450 PF00067.17 EXF86309.1 - 4.6e-45 153.9 0.0 6e-45 153.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PLDc_3 PF13918.1 EXF86309.1 - 0.076 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 PLD-like domain MFS_1 PF07690.11 EXF86310.1 - 1.4e-21 76.6 22.9 1.4e-21 76.6 15.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF86310.1 - 4.7e-05 22.1 1.1 4.7e-05 22.1 0.8 3.3 2 1 1 3 3 3 2 Sugar (and other) transporter DUF4131 PF13567.1 EXF86310.1 - 2 7.7 7.7 9.1 5.6 0.2 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) MFS_1 PF07690.11 EXF86311.1 - 1.7e-37 128.9 53.2 1.7e-37 128.9 36.9 2.6 2 1 0 2 2 2 1 Major Facilitator Superfamily Methyltransf_23 PF13489.1 EXF86312.1 - 3e-09 36.7 0.0 4.5e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF86312.1 - 2.8e-06 27.7 0.0 8.4e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF86312.1 - 5.5e-06 26.7 0.0 1.2e-05 25.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF86312.1 - 7.3e-05 23.3 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF86312.1 - 0.013 15.5 0.0 0.054 13.5 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EXF86312.1 - 0.014 15.7 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SnoaL PF07366.7 EXF86313.1 - 4.6e-12 45.6 1.4 2.1e-11 43.5 0.5 2.0 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.2 EXF86313.1 - 4.1e-06 27.1 1.1 3.3e-05 24.2 0.5 2.1 2 0 0 2 2 2 1 SnoaL-like domain UPF0203 PF05254.7 EXF86313.1 - 0.02 14.7 0.2 2.4 8.0 0.0 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0203) adh_short PF00106.20 EXF86314.1 - 7.2e-20 71.5 0.1 1.5e-19 70.5 0.1 1.5 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EXF86314.1 - 1.7e-05 24.5 0.1 3.3e-05 23.6 0.1 1.4 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EXF86314.1 - 0.0003 20.6 0.0 0.00042 20.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.21 EXF86315.1 - 1.6e-70 237.4 0.0 4e-70 236.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EXF86315.1 - 2.1e-63 214.5 1.0 3.4e-63 213.9 0.7 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EXF86315.1 - 6.7e-62 208.3 0.0 1e-60 204.5 0.0 2.9 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 EXF86315.1 - 1.3e-47 161.7 0.1 4.6e-46 156.7 0.0 3.3 3 0 0 3 3 3 1 short chain dehydrogenase PS-DH PF14765.1 EXF86315.1 - 3e-38 131.6 0.0 6e-38 130.6 0.0 1.5 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EXF86315.1 - 5e-35 119.9 0.1 1.7e-34 118.1 0.1 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N PF00107.21 EXF86315.1 - 2.5e-21 75.5 0.0 2.6e-20 72.2 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF86315.1 - 1.1e-12 48.9 0.0 5.8e-12 46.6 0.0 2.4 2 0 0 2 2 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF86315.1 - 3.2e-08 33.3 0.2 6.9e-08 32.2 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EXF86315.1 - 8e-05 22.8 0.0 0.00028 21.0 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EXF86315.1 - 0.00013 21.0 0.1 0.00029 19.9 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain NAD_binding_10 PF13460.1 EXF86315.1 - 0.017 15.1 0.7 6.4 6.7 0.0 3.1 2 0 0 2 2 2 0 NADH(P)-binding 3Beta_HSD PF01073.14 EXF86315.1 - 0.31 9.6 0.0 0.66 8.6 0.0 1.5 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1759 PF03564.10 EXF86315.1 - 0.39 10.5 0.0 0.92 9.3 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) Glyco_hydro_1 PF00232.13 EXF86316.1 - 2.2e-74 250.3 0.1 6e-74 248.8 0.1 1.6 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 adh_short PF00106.20 EXF86316.1 - 1.2e-23 83.8 0.3 2.3e-23 82.9 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF86316.1 - 9.6e-12 45.1 0.1 1.5e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF86316.1 - 1.8e-06 27.7 0.0 7.2e-06 25.7 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.16 EXF86316.1 - 0.00076 18.9 0.0 0.0012 18.3 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EXF86316.1 - 0.0054 15.4 0.1 0.009 14.7 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_18 PF12847.2 EXF86316.1 - 0.063 13.8 0.0 0.24 12.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain NAD_binding_10 PF13460.1 EXF86316.1 - 0.097 12.6 0.2 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EXF86316.1 - 0.19 11.5 3.3 0.37 10.6 0.8 2.4 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Peptidase_S8 PF00082.17 EXF86317.1 - 1.6e-50 171.8 3.9 2.8e-50 171.0 2.7 1.4 1 0 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EXF86317.1 - 1.9e-16 60.4 0.2 3.9e-16 59.4 0.1 1.6 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) p450 PF00067.17 EXF86318.1 - 1.7e-56 191.7 0.0 2.6e-56 191.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 Ubie_methyltran PF01209.13 EXF86319.1 - 2.7e-12 46.3 0.0 3.2e-12 46.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EXF86319.1 - 4e-11 43.2 0.0 6.2e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF86319.1 - 1.3e-08 34.6 0.0 1.6e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF86319.1 - 4.7e-06 26.9 0.0 6.4e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF86319.1 - 5.6e-06 26.7 0.0 8.6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EXF86319.1 - 0.00038 20.2 0.0 0.00048 19.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF86319.1 - 0.022 14.7 0.0 0.17 11.9 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EXF86319.1 - 0.041 14.4 0.0 0.082 13.4 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Grp1_Fun34_YaaH PF01184.14 EXF86319.1 - 0.072 12.3 0.0 0.099 11.9 0.0 1.2 1 0 0 1 1 1 0 GPR1/FUN34/yaaH family Nucleoporin_C PF03177.9 EXF86320.1 - 7.6e-133 444.1 9.5 9.5e-133 443.7 6.6 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EXF86320.1 - 2e-84 283.8 0.0 3.2e-84 283.1 0.0 1.3 1 0 0 1 1 1 1 Nup133 N terminal like Phasin_2 PF09361.5 EXF86320.1 - 0.042 13.8 1.4 0.068 13.1 0.2 2.0 2 0 0 2 2 2 0 Phasin protein adh_short PF00106.20 EXF86321.1 - 4.6e-23 81.9 0.0 6.5e-23 81.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF86321.1 - 6.6e-13 48.9 0.0 9.1e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF86321.1 - 1.3e-06 28.1 0.0 2.7e-06 27.1 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EXF86321.1 - 0.0023 17.9 0.0 0.0044 17.0 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EXF86321.1 - 0.0036 16.2 0.0 0.0047 15.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.15 EXF86321.1 - 0.013 15.5 0.1 0.037 14.1 0.0 1.8 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Erg28 PF03694.8 EXF86322.1 - 2.9e-40 136.7 0.5 3.7e-40 136.3 0.3 1.1 1 0 0 1 1 1 1 Erg28 like protein GalP_UDP_tr_C PF02744.12 EXF86323.1 - 3.8e-57 192.4 0.2 8.4e-57 191.3 0.1 1.5 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.17 EXF86323.1 - 6.1e-50 169.8 1.1 5.7e-40 137.3 0.0 3.2 2 2 1 3 3 3 2 Galactose-1-phosphate uridyl transferase, N-terminal domain HIT PF01230.18 EXF86323.1 - 1.4e-07 31.9 0.2 3.1e-05 24.4 0.0 2.6 2 1 0 2 2 2 2 HIT domain SWIRM PF04433.12 EXF86324.1 - 2.9e-13 49.7 0.0 7.6e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain ZZ PF00569.12 EXF86324.1 - 2.6e-11 42.8 7.3 4.9e-11 41.9 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EXF86324.1 - 4.7e-07 29.7 0.0 2e-06 27.7 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-C3HC4_2 PF13923.1 EXF86324.1 - 0.21 11.6 3.3 0.53 10.3 2.3 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ubiquitin PF00240.18 EXF86328.1 - 1.2e-20 72.6 0.0 1.9e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EXF86328.1 - 1e-12 47.5 0.0 1.8e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Telomere_Sde2 PF13019.1 EXF86328.1 - 0.00024 20.8 0.0 0.00043 20.0 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Ubiquitin_2 PF14560.1 EXF86328.1 - 0.095 12.9 0.1 0.32 11.2 0.0 1.9 2 0 0 2 2 2 0 Ubiquitin-like domain COesterase PF00135.23 EXF86329.1 - 1.3e-87 294.7 0.0 1.7e-87 294.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF86329.1 - 0.00024 20.7 0.4 0.0015 18.1 0.1 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold SnoaL PF07366.7 EXF86330.1 - 0.004 16.7 0.3 0.021 14.4 0.1 2.1 1 1 1 2 2 2 1 SnoaL-like polyketide cyclase Ribosomal_L37e PF01907.14 EXF86331.1 - 0.04 13.7 1.5 0.094 12.5 1.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L37e Fer4_10 PF13237.1 EXF86331.1 - 0.086 12.6 0.7 0.086 12.6 0.5 1.6 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_2 PF12797.2 EXF86331.1 - 0.56 10.2 3.8 0.5 10.4 0.3 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4 PF00037.22 EXF86331.1 - 1.7 8.3 5.3 0.37 10.4 0.6 2.2 2 0 0 2 2 2 0 4Fe-4S binding domain p450 PF00067.17 EXF86332.1 - 4.1e-71 239.8 0.0 7.3e-71 239.0 0.0 1.3 1 1 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EXF86334.1 - 3.4e-42 144.4 47.7 2.3e-41 141.6 33.4 2.1 2 1 0 2 2 2 1 Major Facilitator Superfamily DUF1345 PF07077.6 EXF86334.1 - 0.028 13.9 2.1 0.082 12.4 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) Gemini_mov PF01708.11 EXF86334.1 - 7.7 6.1 5.8 56 3.3 1.4 3.1 3 1 1 4 4 4 0 Geminivirus putative movement protein MFS_1 PF07690.11 EXF86336.1 - 2.4e-29 102.1 31.2 3.5e-29 101.6 21.4 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF86336.1 - 4.6e-15 55.1 7.0 4.6e-15 55.1 4.8 2.3 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.8 EXF86336.1 - 2e-06 26.2 5.8 4.1e-06 25.3 4.0 1.4 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) OTT_1508_deam PF14441.1 EXF86337.1 - 0.016 15.0 0.1 0.076 12.8 0.1 2.0 1 1 0 1 1 1 0 OTT_1508-like deaminase Ank_2 PF12796.2 EXF86338.1 - 5.1e-18 65.2 2.9 1.9e-05 24.9 0.0 3.7 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EXF86338.1 - 4.7e-16 57.7 6.6 1.2e-06 28.0 0.1 5.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 EXF86338.1 - 8.9e-15 54.7 6.7 0.002 18.6 0.0 5.6 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF86338.1 - 1.3e-12 47.5 4.4 0.008 16.4 0.2 5.3 5 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF86338.1 - 1.4e-08 34.1 2.6 0.008 16.3 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat MFS_1 PF07690.11 EXF86339.1 - 6.1e-10 38.3 34.3 6.1e-10 38.3 23.8 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily F-box-like PF12937.2 EXF86339.1 - 0.00012 21.6 0.1 0.00041 20.0 0.1 1.9 1 0 0 1 1 1 1 F-box-like PROL5-SMR PF15621.1 EXF86339.1 - 0.63 10.4 7.3 1.4 9.4 5.0 1.5 1 0 0 1 1 1 0 Proline-rich submaxillary gland androgen-regulated family MFS_1 PF07690.11 EXF86341.1 - 8.6e-19 67.4 39.7 8.6e-19 67.4 27.5 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF872 PF05915.7 EXF86341.1 - 0.32 10.8 3.9 9.9 6.0 0.3 2.6 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF872) SpoVAB PF13782.1 EXF86341.1 - 2.1 8.3 11.7 0.12 12.4 2.3 3.1 2 2 0 2 2 2 0 Stage V sporulation protein AB CDO_I PF05995.7 EXF86342.1 - 3.7e-37 127.1 0.0 4e-37 127.0 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EXF86342.1 - 0.00024 20.5 0.0 0.00027 20.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) 2OG-FeII_Oxy PF03171.15 EXF86343.1 - 2.7e-11 43.6 0.2 6.8e-10 39.1 0.1 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EXF86343.1 - 4.3e-08 33.7 0.0 1.1e-07 32.4 0.0 1.6 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal FAD_binding_4 PF01565.18 EXF86344.1 - 6.5e-24 83.9 1.0 1.4e-23 82.8 0.7 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF86344.1 - 0.033 14.0 0.0 0.089 12.7 0.0 1.7 1 0 0 1 1 1 0 Berberine and berberine like Oxidored_q1 PF00361.15 EXF86345.1 - 0.0043 16.3 13.9 0.0043 16.3 9.6 1.4 1 1 0 1 1 1 1 NADH-Ubiquinone/plastoquinone (complex I), various chains GMP_synt_C PF00958.17 EXF86345.1 - 0.17 11.6 1.4 1.4 8.6 0.1 2.3 2 0 0 2 2 2 0 GMP synthase C terminal domain FAD_binding_4 PF01565.18 EXF86346.1 - 4.9e-09 35.7 0.2 7.4e-09 35.1 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Peptidase_M50B PF13398.1 EXF86346.1 - 4.4 6.6 4.9 6.2 6.1 3.4 1.2 1 0 0 1 1 1 0 Peptidase M50B-like ADH_zinc_N PF00107.21 EXF86347.1 - 9.1e-23 80.2 0.2 1.4e-22 79.6 0.2 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF86347.1 - 1.3e-12 47.4 0.0 1.6e-11 43.9 0.0 2.3 1 1 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EXF86347.1 - 1.5e-11 45.3 0.0 3e-11 44.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Hydrolase_like PF13242.1 EXF86347.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 HAD-hyrolase-like DUF1283 PF06932.6 EXF86348.1 - 0.086 12.8 2.3 0.15 12.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1283) zf-C2H2 PF00096.21 EXF86349.1 - 1.9e-07 30.9 13.0 0.0021 18.2 1.0 2.6 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EXF86349.1 - 2.3e-07 30.6 11.6 0.00035 20.6 3.2 2.8 2 0 0 2 2 2 2 C2H2-type zinc finger Fungal_trans PF04082.13 EXF86349.1 - 0.00098 18.0 0.0 0.0024 16.8 0.0 1.6 1 1 0 1 1 1 1 Fungal specific transcription factor domain zf-H2C2_2 PF13465.1 EXF86349.1 - 0.0027 17.9 2.3 0.0027 17.9 1.6 4.0 4 0 0 4 4 4 1 Zinc-finger double domain zf-C2H2_jaz PF12171.3 EXF86349.1 - 0.42 10.8 3.0 1.3 9.2 0.9 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding YrhK PF14145.1 EXF86351.1 - 1 9.1 20.7 1.1 9.0 0.3 4.4 2 2 1 3 3 3 0 YrhK-like protein NmrA PF05368.8 EXF86352.1 - 3e-14 52.8 0.0 4.4e-14 52.3 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EXF86352.1 - 2.7e-11 43.7 0.0 3.5e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF2673 PF10880.3 EXF86352.1 - 0.055 13.5 0.0 0.25 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2673) KTSC PF13619.1 EXF86352.1 - 0.08 12.5 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 KTSC domain Epimerase PF01370.16 EXF86352.1 - 0.12 11.7 0.0 0.38 10.1 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Epimerase PF01370.16 EXF86353.1 - 3.6e-15 56.0 0.0 5.7e-15 55.4 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EXF86353.1 - 1.9e-12 46.6 0.1 3.3e-08 32.7 0.1 2.1 2 0 0 2 2 2 2 Male sterility protein 3Beta_HSD PF01073.14 EXF86353.1 - 1.6e-11 43.4 0.0 5.8e-11 41.6 0.0 1.8 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EXF86353.1 - 2.7e-08 34.0 0.0 7.3e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EXF86353.1 - 4.6e-06 25.7 0.1 7.5e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EXF86353.1 - 0.00062 19.7 0.8 1.5 8.7 0.0 3.0 3 0 0 3 3 3 2 short chain dehydrogenase NmrA PF05368.8 EXF86353.1 - 0.0026 17.0 0.0 0.0036 16.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.15 EXF86353.1 - 0.071 13.0 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus FAD_binding_4 PF01565.18 EXF86355.1 - 4.6e-20 71.4 1.3 1.1e-19 70.3 0.9 1.7 1 0 0 1 1 1 1 FAD binding domain Glycos_transf_2 PF00535.21 EXF86355.1 - 0.037 13.6 0.1 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Glycosyl transferase family 2 Zn_clus PF00172.13 EXF86356.1 - 0.0003 20.6 4.1 0.00054 19.8 2.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain G_glu_transpept PF01019.16 EXF86356.1 - 0.038 12.4 0.1 0.42 9.0 0.0 2.1 2 0 0 2 2 2 0 Gamma-glutamyltranspeptidase Amidase PF01425.16 EXF86358.1 - 1.1e-89 301.3 0.0 1.3e-89 301.0 0.0 1.1 1 0 0 1 1 1 1 Amidase IU_nuc_hydro PF01156.14 EXF86359.1 - 5.1e-30 104.7 0.0 6.1e-30 104.5 0.0 1.1 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF4066 PF13278.1 EXF86360.1 - 2.2e-10 40.0 0.0 3.1e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EXF86360.1 - 1.6e-08 34.1 0.0 2.1e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family peroxidase PF00141.18 EXF86362.1 - 9.2e-31 107.1 0.0 1.4e-30 106.5 0.0 1.2 1 0 0 1 1 1 1 Peroxidase WD40 PF00400.27 EXF86363.1 - 0.11 12.4 13.2 0.47 10.4 0.0 4.4 5 0 0 5 5 5 0 WD domain, G-beta repeat PQ-loop PF04193.9 EXF86364.1 - 6.7e-16 57.5 7.1 7.8e-12 44.5 0.6 3.2 3 1 0 3 3 3 2 PQ loop repeat DUF3796 PF12676.2 EXF86364.1 - 0.021 15.0 0.3 0.037 14.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3796) R3H-assoc PF13902.1 EXF86365.1 - 6.6e-21 74.6 2.4 1.2e-20 73.7 1.7 1.4 1 0 0 1 1 1 1 R3H-associated N-terminal domain zf-DHHC PF01529.15 EXF86367.1 - 0.00019 20.8 0.5 0.00019 20.8 0.4 1.8 2 0 0 2 2 2 1 DHHC palmitoyltransferase F-box-like PF12937.2 EXF86368.1 - 0.00027 20.5 1.7 0.00068 19.3 1.2 1.7 1 0 0 1 1 1 1 F-box-like Ank_2 PF12796.2 EXF86368.1 - 0.003 17.8 0.1 0.1 12.9 0.0 2.6 2 2 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EXF86368.1 - 0.049 13.4 3.4 0.12 12.2 0.1 3.1 4 0 0 4 4 4 0 Ankyrin repeat CFEM PF05730.6 EXF86369.1 - 0.019 14.7 2.3 1.2 9.0 0.3 2.1 2 0 0 2 2 2 0 CFEM domain CRAL_TRIO PF00650.15 EXF86371.1 - 1.7e-26 92.6 0.0 2.5e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EXF86371.1 - 2.1e-08 34.1 0.0 4.7e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Acid_PPase PF12689.2 EXF86372.1 - 7.8e-65 217.6 0.0 9.2e-65 217.3 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase HAD_2 PF13419.1 EXF86372.1 - 0.0037 17.4 1.0 0.77 9.9 0.0 3.0 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Glyoxalase PF00903.20 EXF86373.1 - 1.4e-09 37.9 5.6 2.9e-06 27.2 1.5 2.8 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EXF86373.1 - 4.6e-08 33.6 1.7 1e-05 26.1 0.1 2.3 2 0 0 2 2 2 2 Glyoxalase-like domain TPR_2 PF07719.12 EXF86373.1 - 0.019 14.8 0.1 0.27 11.2 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_3 PF07720.7 EXF86373.1 - 0.022 14.5 1.3 0.2 11.4 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EXF86373.1 - 0.068 12.8 0.5 0.73 9.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat SurE PF01975.12 EXF86374.1 - 1.8e-29 102.4 0.0 2.9e-29 101.7 0.0 1.3 1 1 0 1 1 1 1 Survival protein SurE p450 PF00067.17 EXF86376.1 - 2.3e-58 197.8 0.0 2.6e-58 197.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_3 PF01494.14 EXF86377.1 - 1.3e-23 83.6 0.0 1.9e-23 83.0 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EXF86377.1 - 3.2e-11 42.7 2.6 8.8e-05 21.5 0.9 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF86377.1 - 9.3e-08 31.3 1.7 1.5e-07 30.5 1.2 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.9 EXF86377.1 - 1.3e-07 31.6 1.1 1.4e-06 28.3 0.8 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EXF86377.1 - 1.2e-06 28.4 0.3 3e-06 27.1 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EXF86377.1 - 2.5e-06 26.2 0.5 4e-05 22.2 0.2 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EXF86377.1 - 1.7e-05 25.1 0.4 0.0029 17.9 0.1 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EXF86377.1 - 4.2e-05 22.8 2.1 0.00013 21.2 1.4 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EXF86377.1 - 0.0021 17.0 0.7 0.15 10.9 0.8 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Thi4 PF01946.12 EXF86377.1 - 0.0072 15.4 0.5 0.014 14.5 0.4 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EXF86377.1 - 0.0081 16.2 0.0 0.016 15.2 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EXF86377.1 - 0.016 14.1 0.8 0.029 13.2 0.5 1.4 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EXF86377.1 - 0.017 13.7 0.2 0.048 12.2 0.1 1.7 1 1 1 2 2 2 0 Tryptophan halogenase FMO-like PF00743.14 EXF86377.1 - 0.047 11.8 0.3 0.064 11.4 0.2 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like 3HCDH_N PF02737.13 EXF86377.1 - 0.11 12.1 0.1 0.23 11.0 0.1 1.5 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyoxalase PF00903.20 EXF86378.1 - 2.4e-08 34.0 1.8 3.5e-05 23.7 0.3 2.5 2 1 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EXF86378.1 - 8.8e-08 32.7 0.8 0.0021 18.6 0.1 2.2 2 0 0 2 2 2 2 Glyoxalase-like domain FAA_hydrolase PF01557.13 EXF86379.1 - 1.9e-68 230.1 0.0 2.3e-68 229.9 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF2437 PF10370.4 EXF86379.1 - 0.013 15.9 0.2 0.036 14.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2437) Fungal_trans PF04082.13 EXF86380.1 - 2.2e-23 82.4 0.4 2.2e-23 82.4 0.3 1.8 2 0 0 2 2 2 1 Fungal specific transcription factor domain FAD_binding_3 PF01494.14 EXF86381.1 - 1.6e-68 231.3 0.0 2.1e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EXF86381.1 - 0.00053 18.5 0.0 0.001 17.6 0.0 1.5 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.1 EXF86381.1 - 0.00078 19.5 0.0 0.0039 17.2 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EXF86381.1 - 0.00089 18.2 0.0 0.003 16.5 0.0 1.9 1 1 1 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EXF86381.1 - 0.00089 19.2 0.1 0.0028 17.6 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EXF86381.1 - 0.0012 17.8 0.1 0.0026 16.6 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.9 EXF86381.1 - 0.0037 17.1 0.0 0.018 14.9 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EXF86381.1 - 0.0044 16.1 0.0 0.0075 15.3 0.0 1.2 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.17 EXF86381.1 - 0.0061 15.4 0.0 0.0096 14.8 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EXF86381.1 - 0.018 14.0 0.0 0.036 13.0 0.0 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein FAD_oxidored PF12831.2 EXF86381.1 - 0.021 13.9 0.1 0.036 13.1 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase ThiF PF00899.16 EXF86381.1 - 0.14 11.9 0.3 0.32 10.8 0.2 1.5 1 0 0 1 1 1 0 ThiF family NAD_binding_9 PF13454.1 EXF86381.1 - 0.16 11.7 0.5 1 9.0 0.1 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding Laminin_II PF06009.7 EXF86382.1 - 0.0038 16.9 2.4 0.016 14.9 0.5 2.0 1 1 1 2 2 2 1 Laminin Domain II BLOC1_2 PF10046.4 EXF86382.1 - 0.011 15.8 1.6 0.017 15.2 1.1 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF948 PF06103.6 EXF86382.1 - 0.027 14.3 2.3 0.41 10.5 0.6 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) DivIC PF04977.10 EXF86382.1 - 0.12 11.8 0.6 0.52 9.8 0.0 2.1 2 1 0 2 2 2 0 Septum formation initiator NfeD PF01957.13 EXF86383.1 - 1.3 9.1 0.0 1.3 9.1 0.0 2.8 2 1 1 3 3 3 0 NfeD-like C-terminal, partner-binding Caleosin PF05042.8 EXF86384.1 - 3.1e-56 189.6 0.1 4.2e-56 189.2 0.0 1.1 1 0 0 1 1 1 1 Caleosin related protein Glyco_hydro_3 PF00933.16 EXF86385.1 - 1.6e-88 296.5 0.0 2.3e-88 296.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF86385.1 - 7.7e-50 169.5 0.2 9.1e-49 166.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF86385.1 - 2.9e-21 75.1 0.1 5.4e-21 74.3 0.1 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain HET PF06985.6 EXF86386.1 - 3.4e-26 92.0 0.0 9.1e-26 90.6 0.0 1.8 1 1 0 1 1 1 1 Heterokaryon incompatibility protein (HET) Peptidase_C21 PF05381.7 EXF86386.1 - 0.15 12.2 0.0 0.38 10.8 0.0 1.6 1 0 0 1 1 1 0 Tymovirus endopeptidase D-ser_dehydrat PF14031.1 EXF86387.1 - 1.1e-22 80.0 0.0 2.2e-22 79.0 0.0 1.5 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EXF86387.1 - 2.3e-11 43.6 0.2 3.3e-11 43.1 0.1 1.3 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain tRNA_SAD PF07973.9 EXF86388.1 - 1e-08 34.8 2.2 2.2e-08 33.8 0.6 2.1 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain tRNA-synt_2c PF01411.14 EXF86388.1 - 0.1 10.8 0.0 0.17 10.1 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II (A) Baculo_PEP_N PF04512.7 EXF86388.1 - 0.12 12.3 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, N terminus Aa_trans PF01490.13 EXF86389.1 - 1.4e-44 152.2 34.6 1.6e-44 152.0 24.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PAS_9 PF13426.1 EXF86391.1 - 6.8e-15 55.3 0.0 3.8e-13 49.6 0.0 2.6 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 EXF86391.1 - 7.9e-06 25.8 0.0 2.3e-05 24.4 0.0 1.8 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EXF86391.1 - 0.0014 18.3 0.0 0.006 16.3 0.0 2.1 2 0 0 2 2 2 1 PAS fold RGS PF00615.14 EXF86391.1 - 0.023 14.8 0.7 0.28 11.2 0.1 2.5 2 1 0 2 2 2 0 Regulator of G protein signaling domain Ank_2 PF12796.2 EXF86392.1 - 1.1e-21 76.9 0.1 8.6e-08 32.4 0.1 5.7 3 2 3 6 6 6 5 Ankyrin repeats (3 copies) Ank PF00023.25 EXF86392.1 - 1.9e-15 55.7 0.1 0.007 16.1 0.0 7.3 8 1 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.1 EXF86392.1 - 2e-15 56.8 0.2 0.019 15.4 0.0 7.1 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EXF86392.1 - 3.8e-15 55.5 1.7 0.12 12.7 0.0 6.3 5 1 1 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF86392.1 - 1.2e-13 49.8 0.1 0.0014 18.6 0.0 8.2 9 0 0 9 9 9 2 Ankyrin repeat GDI PF00996.13 EXF86392.1 - 0.23 9.7 0.0 0.37 9.0 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Pkinase PF00069.20 EXF86393.1 - 2.9e-13 49.5 0.0 3.9e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF86393.1 - 6.8e-09 35.1 0.0 9.6e-09 34.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EXF86394.1 - 5.4e-20 71.6 0.0 8.2e-20 71.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF86394.1 - 3.4e-11 42.7 0.0 5.3e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pox_ser-thr_kin PF05445.6 EXF86394.1 - 0.084 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF1212 PF06738.7 EXF86395.1 - 6.1e-48 162.8 12.8 4.9e-46 156.6 0.3 2.8 4 0 0 4 4 4 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EXF86395.1 - 3.8e-28 98.0 37.6 1.6e-27 95.9 10.9 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) DUF2301 PF10063.4 EXF86395.1 - 0.016 15.4 5.5 0.016 15.4 3.8 2.2 2 0 0 2 2 2 0 Uncharacterized integral membrane protein (DUF2301) AIF_C PF14721.1 EXF86395.1 - 0.16 12.2 0.2 0.56 10.4 0.2 1.9 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Acyl_transf_3 PF01757.17 EXF86396.1 - 4.1e-23 81.7 32.0 5.1e-21 74.8 13.7 3.1 2 2 0 2 2 2 2 Acyltransferase family Gamma-thionin PF00304.15 EXF86397.1 - 0.28 11.2 26.2 0.32 11.0 2.3 3.4 3 0 0 3 3 3 0 Gamma-thionin family Colipase-like PF15083.1 EXF86397.1 - 0.84 9.6 14.9 6.4 6.7 0.7 3.1 3 0 0 3 3 3 0 Colipase-like Colipase PF01114.13 EXF86397.1 - 9.4 5.8 30.2 0.31 10.5 3.3 3.3 3 0 0 3 3 3 0 Colipase, N-terminal domain Methyltransf_23 PF13489.1 EXF86398.1 - 9.5e-25 87.1 0.1 1.4e-24 86.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF86398.1 - 4.3e-09 36.7 0.0 4.2e-08 33.5 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF86398.1 - 2.2e-08 34.4 0.0 7.7e-08 32.7 0.0 1.9 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF86398.1 - 2.7e-08 33.5 0.0 7.2e-08 32.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF86398.1 - 3.1e-08 34.1 0.0 5.4e-07 30.1 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF86398.1 - 2.3e-05 24.6 0.0 6.9e-05 23.1 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 EXF86398.1 - 0.0088 15.4 0.0 0.031 13.6 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase small domain FtsJ PF01728.14 EXF86398.1 - 0.024 14.6 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EXF86398.1 - 0.088 12.8 0.0 0.16 12.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_16 PF10294.4 EXF86398.1 - 0.095 12.1 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 EXF86398.1 - 0.15 11.1 0.0 19 4.2 0.0 2.4 2 1 0 2 2 2 0 ubiE/COQ5 methyltransferase family Transferase PF02458.10 EXF86399.1 - 7.4e-06 24.6 0.0 0.0033 15.9 0.0 2.3 2 0 0 2 2 2 2 Transferase family Clp1 PF06807.9 EXF86400.1 - 1.2e-18 67.5 0.0 2e-18 66.8 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EXF86400.1 - 9.8e-08 31.8 0.0 3.3e-07 30.0 0.0 1.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EXF86400.1 - 0.00027 20.8 0.3 0.0021 17.9 0.1 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EXF86400.1 - 0.0015 18.1 0.1 0.0031 17.0 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EXF86400.1 - 0.0038 17.2 0.0 0.0069 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain KTI12 PF08433.5 EXF86400.1 - 0.023 13.9 0.0 0.31 10.2 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_33 PF13671.1 EXF86400.1 - 0.034 14.0 0.0 0.14 12.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EXF86400.1 - 0.044 13.7 0.1 0.1 12.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain FeoB_N PF02421.13 EXF86400.1 - 0.052 12.8 0.0 0.18 11.0 0.0 1.9 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_19 PF13245.1 EXF86400.1 - 0.074 12.8 0.3 0.18 11.5 0.2 1.6 1 0 0 1 1 1 0 Part of AAA domain IstB_IS21 PF01695.12 EXF86400.1 - 0.098 12.0 0.0 0.54 9.6 0.0 2.2 3 0 0 3 3 3 0 IstB-like ATP binding protein NAD_binding_10 PF13460.1 EXF86400.1 - 0.12 12.3 0.0 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 NADH(P)-binding FtsK_SpoIIIE PF01580.13 EXF86400.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Pmp3 PF01679.12 EXF86401.1 - 1.5e-20 72.6 6.9 1.9e-20 72.3 4.8 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF2201_N PF13203.1 EXF86401.1 - 0.03 13.4 2.6 0.05 12.7 1.8 1.3 1 1 0 1 1 1 0 Putative metallopeptidase domain Arb1 PF09692.5 EXF86402.1 - 6.3e-93 311.7 0.0 7.3e-93 311.5 0.0 1.0 1 0 0 1 1 1 1 Argonaute siRNA chaperone (ARC) complex subunit Arb1 IPK PF03770.11 EXF86403.1 - 4.2e-52 176.6 0.0 5.5e-52 176.2 0.0 1.1 1 0 0 1 1 1 1 Inositol polyphosphate kinase OB_NTP_bind PF07717.11 EXF86404.1 - 1.1e-28 99.3 0.0 5e-28 97.2 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EXF86404.1 - 6.8e-28 96.6 0.2 2.8e-27 94.7 0.2 2.1 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EXF86404.1 - 3.3e-11 42.8 0.0 9.1e-11 41.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain S1 PF00575.18 EXF86404.1 - 3.5e-11 43.0 0.8 6.9e-11 42.0 0.6 1.5 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.1 EXF86404.1 - 4.6e-07 30.0 0.0 1.2e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EXF86404.1 - 1.3e-06 27.9 0.1 2.8e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase T2SE PF00437.15 EXF86404.1 - 0.00024 20.0 0.0 0.00057 18.8 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.1 EXF86404.1 - 0.0011 18.5 0.2 0.0055 16.2 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EXF86404.1 - 0.024 14.3 0.1 0.067 12.9 0.1 1.8 1 0 0 1 1 1 0 Part of AAA domain AAA_14 PF13173.1 EXF86404.1 - 0.05 13.4 0.2 0.34 10.8 0.1 2.2 1 1 0 1 1 1 0 AAA domain PhoH PF02562.11 EXF86404.1 - 0.06 12.5 0.0 0.15 11.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein ABC_tran PF00005.22 EXF86404.1 - 0.086 13.1 0.1 1.2 9.4 0.0 2.5 1 1 1 2 2 2 0 ABC transporter AAA_29 PF13555.1 EXF86404.1 - 0.17 11.4 0.0 0.42 10.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.17 EXF86404.1 - 0.2 10.4 0.0 0.32 9.7 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Reticulon PF02453.12 EXF86407.1 - 3.4e-20 72.3 0.0 5.1e-20 71.7 0.0 1.2 1 0 0 1 1 1 1 Reticulon DUF883 PF05957.8 EXF86407.1 - 0.94 9.9 6.8 3 8.3 3.8 2.5 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF883) Syntaxin-6_N PF09177.6 EXF86407.1 - 2.9 8.3 5.4 0.65 10.4 0.3 2.5 3 1 1 4 4 4 0 Syntaxin 6, N-terminal Alginate_lyase PF05426.7 EXF86408.1 - 1.1e-19 70.8 0.1 2.4e-19 69.7 0.1 1.5 1 1 0 1 1 1 1 Alginate lyase PA14_2 PF10528.4 EXF86409.1 - 5.1e-30 103.7 17.4 1.5e-20 73.2 4.0 3.0 3 0 0 3 3 3 2 GLEYA domain PA14 PF07691.7 EXF86409.1 - 4.4e-20 71.8 0.8 3.2e-10 39.8 0.4 2.6 2 0 0 2 2 2 2 PA14 domain C1q PF00386.16 EXF86409.1 - 1.7 8.6 7.1 7.5 6.5 0.5 2.4 2 0 0 2 2 2 0 C1q domain Glyco_hydro_28 PF00295.12 EXF86411.1 - 4.5e-07 29.1 3.9 1.1e-06 27.8 2.7 1.5 1 1 0 1 1 1 1 Glycosyl hydrolases family 28 Glyco_hydro_49 PF03718.8 EXF86411.1 - 5.3e-05 21.4 0.4 5.3e-05 21.4 0.3 2.8 2 1 1 3 3 3 2 Glycosyl hydrolase family 49 Beta_helix PF13229.1 EXF86411.1 - 0.00059 19.6 20.0 0.0014 18.3 7.8 2.7 1 1 1 2 2 2 2 Right handed beta helix region NosD PF05048.8 EXF86411.1 - 0.0076 15.4 1.6 0.0076 15.4 1.1 1.6 1 1 0 1 1 1 1 Periplasmic copper-binding protein (NosD) Beta-lactamase PF00144.19 EXF86414.1 - 5.3e-42 144.0 0.0 7.2e-42 143.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Beta-lactamase2 PF13354.1 EXF86414.1 - 0.028 13.8 0.0 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 Beta-lactamase enzyme family DEAD PF00270.24 EXF86415.1 - 2.4e-44 150.8 0.0 5.6e-44 149.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF4217 PF13959.1 EXF86415.1 - 2e-26 91.2 0.2 4.5e-26 90.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C PF00271.26 EXF86415.1 - 1.9e-19 69.2 0.0 5.2e-19 67.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EXF86415.1 - 0.00036 20.4 0.0 0.0011 18.8 0.0 1.9 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.1 EXF86415.1 - 0.0032 17.4 0.0 0.0096 15.8 0.0 1.8 1 0 0 1 1 1 1 Helicase C-terminal domain AAA_19 PF13245.1 EXF86415.1 - 0.021 14.5 0.0 0.51 10.1 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain Gly_rich PF12810.2 EXF86415.1 - 0.092 12.3 0.9 0.16 11.5 0.6 1.3 1 0 0 1 1 1 0 Glycine rich protein Sad1_UNC PF07738.8 EXF86416.1 - 3.9e-09 36.3 0.0 2.2e-08 33.9 0.0 2.1 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal DUF445 PF04286.7 EXF86416.1 - 0.056 12.9 2.0 0.86 9.0 1.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF445) Epimerase PF01370.16 EXF86417.1 - 1.6e-44 152.1 0.0 2e-44 151.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EXF86417.1 - 1.4e-25 89.0 0.0 2.3e-25 88.3 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EXF86417.1 - 8.5e-19 67.3 0.1 2.4e-18 65.8 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EXF86417.1 - 8.6e-16 57.6 0.0 1.1e-13 50.8 0.0 2.2 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EXF86417.1 - 5.4e-14 52.4 0.0 8.5e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EXF86417.1 - 2e-13 49.8 0.0 3.3e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EXF86417.1 - 4e-10 39.9 0.0 7e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EXF86417.1 - 7.6e-10 38.7 0.0 1.4e-09 37.8 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EXF86417.1 - 9.5e-10 37.8 0.0 2.3e-09 36.5 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein UDPG_MGDP_dh_N PF03721.9 EXF86417.1 - 0.0043 16.4 0.1 0.0072 15.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Saccharop_dh PF03435.13 EXF86417.1 - 0.0072 15.3 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 EXF86417.1 - 0.013 14.7 0.0 0.028 13.6 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family Methyltransf_18 PF12847.2 EXF86417.1 - 0.065 13.8 0.0 7.5 7.1 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain ADH_zinc_N PF00107.21 EXF86418.1 - 3.2e-34 117.2 0.1 5e-34 116.6 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF86418.1 - 1e-18 68.4 0.1 2.3e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EXF86418.1 - 3.3e-11 42.8 0.0 2.2e-10 40.2 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain NAD_binding_10 PF13460.1 EXF86418.1 - 0.0013 18.7 0.2 0.0046 16.9 0.1 1.9 2 0 0 2 2 2 1 NADH(P)-binding CPSase_L_chain PF00289.17 EXF86418.1 - 0.042 13.9 0.1 0.12 12.4 0.1 1.8 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain adh_short PF00106.20 EXF86418.1 - 0.055 13.3 0.8 0.17 11.7 0.5 2.0 1 1 0 1 1 1 0 short chain dehydrogenase Methyltransf_15 PF09445.5 EXF86418.1 - 0.092 12.2 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Ank_2 PF12796.2 EXF86419.1 - 1.2e-60 201.8 34.2 1.2e-09 38.4 0.0 15.0 5 3 9 14 14 14 14 Ankyrin repeats (3 copies) Ank PF00023.25 EXF86419.1 - 1.3e-26 90.9 46.3 1.3e-05 24.7 0.0 21.7 24 0 0 24 24 24 7 Ankyrin repeat Ank_4 PF13637.1 EXF86419.1 - 7e-21 74.1 17.0 0.0093 16.4 0.0 15.8 16 2 1 17 17 17 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF86419.1 - 4.9e-20 69.6 25.1 0.0026 17.8 0.0 19.7 24 0 0 24 24 24 5 Ankyrin repeat Ank_5 PF13857.1 EXF86419.1 - 1.8e-13 50.2 28.0 1e-06 28.7 0.0 14.5 16 3 1 17 17 17 2 Ankyrin repeats (many copies) Rer1 PF03248.8 EXF86420.1 - 0.083 12.4 3.4 5.9 6.4 0.5 2.4 2 0 0 2 2 2 0 Rer1 family DUF3021 PF11457.3 EXF86420.1 - 1.4 8.7 9.8 0.68 9.8 4.9 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3021) Peptidase_M28 PF04389.12 EXF86422.1 - 6.8e-31 107.3 0.0 1.2e-30 106.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EXF86422.1 - 2.5e-16 59.1 0.9 5e-16 58.2 0.6 1.5 1 0 0 1 1 1 1 PA domain Peptidase_M20 PF01546.23 EXF86422.1 - 2.4e-05 23.9 0.1 4.4e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peroxidase_2 PF01328.12 EXF86423.1 - 9.4e-46 155.9 0.0 1.2e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 Peroxidase, family 2 Tyrosinase PF00264.15 EXF86424.1 - 3e-48 164.9 0.7 3.9e-48 164.5 0.5 1.1 1 0 0 1 1 1 1 Common central domain of tyrosinase Methyltransf_23 PF13489.1 EXF86425.1 - 1.9e-19 69.9 0.0 3e-19 69.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF86425.1 - 8.7e-12 45.3 0.0 1.9e-11 44.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF86425.1 - 1.4e-11 44.2 0.0 1.8e-10 40.6 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF86425.1 - 9.2e-10 38.8 0.0 8.9e-09 35.7 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF86425.1 - 1.2e-08 35.4 0.1 3.1e-07 30.9 0.1 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF86425.1 - 2.8e-07 30.8 0.0 1.2e-05 25.6 0.0 3.1 3 1 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 EXF86425.1 - 1e-06 28.0 0.0 1.6e-05 24.1 0.0 2.6 2 1 0 2 2 2 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EXF86425.1 - 0.0025 17.2 0.0 0.018 14.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EXF86425.1 - 0.0028 16.7 0.0 0.033 13.2 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_26 PF13659.1 EXF86425.1 - 0.012 15.6 0.0 5.1 7.1 0.0 2.6 1 1 1 2 2 2 0 Methyltransferase domain PrmA PF06325.8 EXF86425.1 - 0.042 12.9 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) FtsJ PF01728.14 EXF86425.1 - 0.052 13.5 0.0 0.082 12.8 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase HrpF PF06266.7 EXF86425.1 - 0.078 13.1 0.9 0.18 11.9 0.6 1.6 1 0 0 1 1 1 0 HrpF protein CMAS PF02353.15 EXF86425.1 - 0.081 11.9 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.4 EXF86425.1 - 0.13 11.6 0.0 0.25 10.7 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_8 PF05148.10 EXF86425.1 - 0.17 11.4 0.0 0.3 10.6 0.0 1.4 1 0 0 1 1 1 0 Hypothetical methyltransferase Claudin_2 PF13903.1 EXF86426.1 - 0.11 12.2 3.3 2.7 7.6 2.3 2.2 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Sdh_cyt PF01127.17 EXF86426.1 - 0.55 10.0 3.4 0.3 10.9 0.3 1.9 2 1 0 2 2 2 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit MIP PF00230.15 EXF86427.1 - 1.5e-41 142.3 13.8 1.8e-41 142.1 9.5 1.1 1 0 0 1 1 1 1 Major intrinsic protein Sugar_tr PF00083.19 EXF86428.1 - 2e-64 217.8 18.3 5.8e-63 213.0 12.7 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF86428.1 - 1e-11 44.1 39.6 5.3e-07 28.6 8.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4212 PF13937.1 EXF86428.1 - 0.008 16.1 4.4 0.015 15.2 0.1 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4212) Ank_2 PF12796.2 EXF86429.1 - 1.9e-20 72.9 0.0 1.8e-08 34.5 0.0 4.4 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.25 EXF86429.1 - 2.3e-19 68.1 0.0 1.1e-06 28.1 0.0 4.1 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EXF86429.1 - 3.3e-18 65.2 0.1 2.9e-07 30.4 0.0 4.2 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EXF86429.1 - 2e-13 49.1 0.1 0.0013 18.7 0.0 5.0 3 1 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.1 EXF86429.1 - 1.1e-12 48.0 0.0 0.0012 19.3 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Peptidase_M28 PF04389.12 EXF86430.1 - 1.3e-36 126.0 0.0 2.3e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 PA PF02225.17 EXF86430.1 - 3e-12 46.1 0.2 1.1e-11 44.3 0.0 2.0 2 0 0 2 2 2 1 PA domain Peptidase_M20 PF01546.23 EXF86430.1 - 6.8e-05 22.4 0.0 0.00011 21.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 MFS_1 PF07690.11 EXF86431.1 - 7.1e-30 103.8 18.1 9.3e-29 100.2 11.3 2.0 2 0 0 2 2 2 2 Major Facilitator Superfamily TauD PF02668.11 EXF86433.1 - 3e-32 112.3 0.0 4.2e-32 111.8 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Ax_dynein_light PF10211.4 EXF86433.1 - 0.048 13.4 0.0 0.079 12.7 0.0 1.2 1 0 0 1 1 1 0 Axonemal dynein light chain MFS_1 PF07690.11 EXF86434.1 - 2.8e-17 62.4 7.1 3.8e-17 62.0 4.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.19 EXF86434.1 - 0.00019 20.1 5.1 0.00024 19.8 3.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter DUF4383 PF14325.1 EXF86434.1 - 0.62 10.0 4.8 1.1 9.2 3.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4383) TnpB_IS66 PF05717.8 EXF86435.1 - 0.057 12.8 0.0 0.098 12.1 0.0 1.3 1 0 0 1 1 1 0 IS66 Orf2 like protein Abhydrolase_6 PF12697.2 EXF86436.1 - 3.4e-25 89.2 1.7 4.2e-25 88.9 1.2 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EXF86436.1 - 5e-16 58.9 0.2 4.4e-15 55.8 0.0 2.4 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EXF86436.1 - 3.1e-13 49.7 0.0 4.1e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EXF86436.1 - 0.0029 17.4 0.0 0.0089 15.8 0.0 1.8 2 0 0 2 2 2 1 Putative lysophospholipase PGAP1 PF07819.8 EXF86436.1 - 0.11 12.0 0.1 0.22 11.0 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein Ser_hydrolase PF06821.8 EXF86436.1 - 0.14 11.7 1.2 0.15 11.6 0.1 1.6 2 0 0 2 2 2 0 Serine hydrolase Methyltransf_23 PF13489.1 EXF86437.1 - 2.1e-17 63.3 0.0 4.3e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF86437.1 - 1.9e-08 34.8 0.0 3e-07 30.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF86437.1 - 1.1e-07 31.5 0.0 3.6e-06 26.6 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF86437.1 - 1.3e-07 32.0 0.0 3.1e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF86437.1 - 5.2e-06 26.8 0.1 8.4e-05 22.9 0.0 2.7 2 1 0 2 2 2 1 Methyltransferase domain HNH_2 PF13391.1 EXF86437.1 - 8.2e-05 22.3 0.2 0.00018 21.2 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease Methyltransf_25 PF13649.1 EXF86437.1 - 0.041 14.2 0.0 0.14 12.5 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EXF86437.1 - 0.088 12.7 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.9 EXF86437.1 - 0.12 11.7 0.0 0.29 10.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.8 EXF86437.1 - 0.13 11.3 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Oxidored_FMN PF00724.15 EXF86438.1 - 1.9e-68 231.0 0.0 2.3e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EXF86438.1 - 0.00039 19.3 0.0 0.00095 18.0 0.0 1.7 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) FMN_dh PF01070.13 EXF86438.1 - 0.0085 14.9 2.5 0.01 14.6 1.0 1.7 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 EXF86438.1 - 0.041 13.1 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 Histidine biosynthesis protein DHO_dh PF01180.16 EXF86438.1 - 0.062 12.2 0.0 0.088 11.7 0.0 1.3 1 0 0 1 1 1 0 Dihydroorotate dehydrogenase Zn_clus PF00172.13 EXF86439.1 - 2.1e-09 37.1 11.6 3.8e-09 36.3 8.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans PF04082.13 EXF86439.1 - 4.5e-05 22.4 0.0 6.6e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sld5 PF05916.6 EXF86440.1 - 5e-26 91.0 0.0 7.6e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein DUF1445 PF07286.7 EXF86442.1 - 5.3e-57 191.4 0.1 7.2e-57 191.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1445) Imm44 PF15584.1 EXF86442.1 - 0.1 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 Immunity protein 44 Aldo_ket_red PF00248.16 EXF86443.1 - 7.1e-68 228.4 0.0 8.1e-68 228.2 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Rhomboid PF01694.17 EXF86444.1 - 0.0098 15.9 3.7 0.0098 15.9 2.6 2.3 2 1 0 2 2 2 1 Rhomboid family SNF2_N PF00176.18 EXF86445.1 - 2.1e-68 230.3 0.4 6.8e-68 228.6 0.1 1.9 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EXF86445.1 - 1.2e-17 63.5 0.0 3.7e-17 61.9 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EXF86445.1 - 1.5e-05 24.5 0.0 4.3e-05 23.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Homez PF11569.3 EXF86445.1 - 0.059 12.4 2.1 0.064 12.3 0.1 2.1 2 0 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez tRNA_bind PF01588.15 EXF86446.1 - 2e-23 82.0 0.4 1e-22 79.7 0.3 2.1 1 1 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 EXF86446.1 - 7.3e-09 36.0 0.1 2.4e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EXF86446.1 - 8.6e-05 22.3 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EXF86446.1 - 0.00014 21.8 0.3 0.0014 18.5 0.0 2.3 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain HSP9_HSP12 PF04119.7 EXF86446.1 - 0.034 14.2 3.4 0.087 12.9 2.4 1.7 1 0 0 1 1 1 0 Heat shock protein 9/12 NUC153 PF08159.7 EXF86448.1 - 9.6e-13 47.4 0.9 9.6e-13 47.4 0.6 2.8 2 1 0 2 2 2 1 NUC153 domain SNF2_N PF00176.18 EXF86449.1 - 3e-39 134.5 0.0 7.6e-39 133.2 0.0 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EXF86449.1 - 4.4e-11 42.4 0.0 9.5e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EXF86449.1 - 0.0014 18.2 6.8 0.0035 16.9 4.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EXF86449.1 - 0.014 15.2 3.8 0.033 14.0 2.7 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EXF86449.1 - 0.014 15.0 7.1 0.032 13.9 4.9 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EXF86449.1 - 0.015 15.3 6.5 0.033 14.2 4.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EXF86449.1 - 0.016 14.8 4.2 0.06 13.0 2.7 2.1 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.1 EXF86449.1 - 0.046 13.5 8.6 0.11 12.3 5.9 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_6 PF14835.1 EXF86449.1 - 0.12 12.1 3.3 0.25 11.1 2.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Git3 PF11710.3 EXF86450.1 - 2.6e-65 219.7 11.3 4.5e-65 219.0 7.8 1.3 1 0 0 1 1 1 1 G protein-coupled glucose receptor regulating Gpa2 Git3_C PF11970.3 EXF86450.1 - 5.4e-14 51.7 0.1 5.4e-14 51.7 0.1 1.8 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.16 EXF86450.1 - 2.4e-07 30.1 0.0 4e-07 29.4 0.0 1.3 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) SNF2_N PF00176.18 EXF86451.1 - 6.5e-47 159.7 0.1 1.3e-46 158.7 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EXF86451.1 - 6.5e-09 35.5 0.0 2e-08 33.9 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.1 EXF86451.1 - 2.5e-08 33.7 9.4 9.1e-08 31.9 6.5 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EXF86451.1 - 5.5e-06 25.9 7.8 1.4e-05 24.6 5.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EXF86451.1 - 7.2e-06 25.5 10.7 1.7e-05 24.3 7.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EXF86451.1 - 9.4e-06 25.3 8.3 3e-05 23.7 5.8 2.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EXF86451.1 - 0.00049 19.7 10.8 0.0014 18.3 7.5 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 EXF86451.1 - 0.0035 17.1 2.3 0.0076 16.0 1.6 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EXF86451.1 - 0.0067 15.9 4.9 0.021 14.3 3.4 1.9 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EXF86451.1 - 0.031 14.1 8.9 0.076 12.9 6.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EXF86451.1 - 0.75 9.5 10.6 0.27 10.9 4.3 2.7 2 0 0 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.2 EXF86451.1 - 1.1 9.4 10.1 0.11 12.5 3.3 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger GATase PF00117.23 EXF86452.1 - 9.4e-12 44.7 0.0 1.3e-11 44.2 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I DHHA2 PF02833.9 EXF86453.1 - 8.4e-22 77.7 0.0 1.4e-21 77.0 0.0 1.3 1 0 0 1 1 1 1 DHHA2 domain DHH PF01368.15 EXF86453.1 - 1.3e-11 44.3 0.0 2e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 DHH family S1-P1_nuclease PF02265.11 EXF86454.1 - 3.1e-69 233.3 0.0 3.6e-69 233.2 0.0 1.0 1 0 0 1 1 1 1 S1/P1 Nuclease YjeF_N PF03853.10 EXF86454.1 - 0.068 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 YjeF-related protein N-terminus Oligomerisation PF02410.10 EXF86455.1 - 5.1e-06 26.4 0.0 0.006 16.6 0.0 2.7 2 0 0 2 2 2 2 Oligomerisation domain BBP1_C PF15272.1 EXF86455.1 - 0.0072 15.8 0.1 0.014 14.9 0.1 1.4 1 0 0 1 1 1 1 Spindle pole body component BBP1, C-terminal TIMELESS PF04821.9 EXF86455.1 - 0.17 11.1 0.2 0.36 10.0 0.0 1.6 2 0 0 2 2 2 0 Timeless protein RNA_pol PF00940.14 EXF86456.1 - 1.7e-162 540.5 0.0 2.9e-162 539.8 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EXF86456.1 - 2.3e-79 266.9 0.8 2.3e-79 266.9 0.6 1.7 2 0 0 2 2 2 1 DNA-directed RNA polymerase N-terminal Methyltransf_23 PF13489.1 EXF86457.1 - 2e-13 50.3 0.0 2.7e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF86457.1 - 0.00025 20.6 0.0 0.00036 20.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF86457.1 - 0.0017 18.8 0.0 0.0033 17.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EXF86457.1 - 0.002 18.5 0.0 0.0038 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ank_4 PF13637.1 EXF86458.1 - 1.4e-17 63.6 0.1 1.6e-10 41.2 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EXF86458.1 - 2.7e-17 62.8 0.1 1.6e-09 37.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EXF86458.1 - 6.9e-14 51.5 0.0 1.2e-08 34.9 0.0 2.9 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EXF86458.1 - 2.8e-13 48.9 0.3 0.00012 21.7 0.0 4.0 4 1 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EXF86458.1 - 8.7e-11 40.9 0.8 0.041 14.1 0.3 4.5 3 1 0 3 3 3 2 Ankyrin repeat p450 PF00067.17 EXF86459.1 - 2.2e-49 168.2 0.0 2.8e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_23 PF13489.1 EXF86460.1 - 4.7e-20 71.9 0.0 7e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EXF86460.1 - 5.5e-06 26.9 0.0 0.0003 21.3 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EXF86460.1 - 1.9e-05 24.2 0.0 0.099 12.2 0.0 2.7 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EXF86460.1 - 3.1e-05 24.3 0.0 0.00011 22.6 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EXF86460.1 - 4e-05 24.0 0.0 0.00058 20.2 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EXF86460.1 - 0.0014 18.9 0.0 0.012 15.9 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EXF86460.1 - 0.03 14.3 0.0 0.24 11.4 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EXF86460.1 - 0.049 13.6 0.0 0.084 12.8 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase UPF0258 PF06789.7 EXF86460.1 - 0.074 13.1 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) PrmA PF06325.8 EXF86460.1 - 0.17 10.9 0.0 0.53 9.3 0.0 1.7 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) GMC_oxred_N PF00732.14 EXF86461.1 - 1.5e-63 214.7 0.0 1.9e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF86461.1 - 7.1e-30 104.1 0.2 1.4e-29 103.2 0.1 1.5 1 0 0 1 1 1 1 GMC oxidoreductase DAO PF01266.19 EXF86461.1 - 0.00014 20.9 0.1 0.0019 17.2 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EXF86461.1 - 0.00018 20.4 0.0 0.5 9.1 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EXF86461.1 - 0.0029 16.7 0.1 0.007 15.4 0.1 1.6 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EXF86461.1 - 0.0041 17.1 0.0 0.011 15.6 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EXF86461.1 - 0.014 14.3 0.0 0.025 13.5 0.0 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EXF86461.1 - 0.022 14.6 0.0 1.5 8.6 0.0 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.11 EXF86462.1 - 1e-11 44.2 53.5 7.6e-08 31.4 12.7 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EXF86462.1 - 2.2e-06 26.1 27.0 4.7e-06 25.0 18.7 1.3 1 1 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EXF86462.1 - 0.23 9.9 33.5 0.0059 15.2 9.3 2.8 2 1 0 2 2 2 0 Sugar (and other) transporter AA_permease PF00324.16 EXF86463.1 - 3.5e-116 388.3 33.0 4e-116 388.2 22.8 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF86463.1 - 5.8e-32 110.7 36.5 7e-32 110.4 25.3 1.0 1 0 0 1 1 1 1 Amino acid permease zf-TAZ PF02135.11 EXF86464.1 - 0.15 12.1 2.0 0.93 9.5 0.1 2.2 2 0 0 2 2 2 0 TAZ zinc finger FpoO PF10621.4 EXF86464.1 - 0.25 11.3 3.5 0.57 10.2 1.5 2.1 1 1 1 2 2 2 0 F420H2 dehydrogenase subunit FpoO GMC_oxred_N PF00732.14 EXF86465.1 - 4.3e-52 177.1 0.0 7.8e-52 176.2 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EXF86465.1 - 1.3e-37 129.2 0.0 2.4e-37 128.4 0.0 1.5 1 0 0 1 1 1 1 GMC oxidoreductase FAD_binding_2 PF00890.19 EXF86465.1 - 1e-08 34.4 2.6 0.00051 19.0 0.7 2.5 3 0 0 3 3 3 2 FAD binding domain DAO PF01266.19 EXF86465.1 - 1.3e-08 34.1 1.9 0.00012 21.1 1.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EXF86465.1 - 0.00036 20.4 0.6 0.001 18.9 0.3 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EXF86465.1 - 0.00086 19.4 0.1 0.41 10.6 0.2 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EXF86465.1 - 0.0032 16.4 0.6 0.0046 15.9 0.1 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.9 EXF86465.1 - 0.0057 15.1 1.4 0.0082 14.6 0.4 1.5 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.1 EXF86465.1 - 0.007 16.3 1.7 0.021 14.8 1.2 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EXF86465.1 - 0.021 13.9 0.1 0.039 13.0 0.1 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.17 EXF86465.1 - 0.028 13.2 2.2 0.54 9.0 0.4 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A Trp_halogenase PF04820.9 EXF86465.1 - 0.064 11.8 0.8 0.09 11.3 0.5 1.1 1 0 0 1 1 1 0 Tryptophan halogenase DctA-YdbH PF11739.3 EXF86465.1 - 0.09 12.2 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Dicarboxylate transport ADH_zinc_N PF00107.21 EXF86467.1 - 2.1e-22 79.0 0.0 3.2e-22 78.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF86467.1 - 1.1e-05 26.3 0.0 2.3e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.3 EXF86467.1 - 0.12 11.4 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) Sugar_tr PF00083.19 EXF86468.1 - 4.2e-104 348.6 17.5 4.9e-104 348.4 12.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EXF86468.1 - 3.5e-21 75.3 34.3 5e-16 58.3 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_tranf_2_3 PF13641.1 EXF86469.1 - 7e-16 58.7 0.1 9.5e-16 58.2 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EXF86469.1 - 1e-05 24.8 0.1 0.0052 16.0 0.0 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 21 Glycos_transf_2 PF00535.21 EXF86469.1 - 6.6e-05 22.6 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF832 PF05734.6 EXF86470.1 - 0.064 12.4 0.1 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus protein of unknown function (DUF832) Cyd_oper_YbgE PF09600.5 EXF86470.1 - 0.14 12.3 4.0 0.21 11.7 2.2 1.8 1 1 0 1 1 1 0 Cyd operon protein YbgE (Cyd_oper_YbgE) p450 PF00067.17 EXF86471.1 - 1.3e-66 225.1 0.0 1.5e-66 224.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AA_permease PF00324.16 EXF86472.1 - 1.8e-115 386.0 42.4 2e-115 385.8 29.4 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.1 EXF86472.1 - 5.3e-38 130.6 49.7 7.7e-38 130.1 34.4 1.2 1 0 0 1 1 1 1 Amino acid permease Sec61_beta PF03911.11 EXF86472.1 - 8.1 6.3 9.4 0.17 11.7 0.9 2.5 2 0 0 2 2 2 0 Sec61beta family Fungal_trans_2 PF11951.3 EXF86473.1 - 2.5e-07 29.6 0.8 0.0011 17.6 0.0 2.3 2 0 0 2 2 2 2 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF86473.1 - 5.7e-06 26.1 5.7 5.7e-06 26.1 4.0 2.1 2 0 0 2 2 2 1 Fungal Zn(2)-Cys(6) binuclear cluster domain p450 PF00067.17 EXF86474.1 - 6e-79 265.7 0.0 8e-79 265.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 FAD_binding_1 PF00667.15 EXF86474.1 - 1.8e-36 125.6 0.0 4.2e-36 124.4 0.0 1.6 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EXF86474.1 - 1.5e-24 86.6 0.0 2.9e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EXF86474.1 - 1.2e-11 45.0 0.0 2.9e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EXF86474.1 - 0.00038 20.4 0.0 0.0014 18.5 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin domain Flavodoxin_NdrI PF07972.6 EXF86474.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 NrdI Flavodoxin like Peptidase_C39_2 PF13529.1 EXF86474.1 - 0.18 12.1 0.0 0.39 11.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase_C39 like family DcpS_C PF11969.3 EXF86475.1 - 2e-30 105.3 0.1 3.5e-30 104.6 0.1 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DcpS PF05652.7 EXF86475.1 - 1.2e-28 99.7 0.0 1.9e-28 99.0 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme (DcpS) N-terminal GILT PF03227.11 EXF86476.1 - 8.3e-13 48.1 0.1 1.5e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) DUF2573 PF10835.3 EXF86476.1 - 0.062 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2573) PSI_8 PF00796.13 EXF86476.1 - 0.64 9.6 2.5 1.5 8.5 1.8 1.6 1 0 0 1 1 1 0 Photosystem I reaction centre subunit VIII Hexokinase_1 PF00349.16 EXF86477.1 - 5.1e-20 71.6 0.0 4.1e-19 68.7 0.0 2.3 2 1 0 2 2 2 1 Hexokinase Hexokinase_2 PF03727.11 EXF86477.1 - 1.4e-12 47.3 0.0 1.5e-11 44.0 0.0 2.4 2 1 0 2 2 2 1 Hexokinase SRP-alpha_N PF04086.8 EXF86478.1 - 5.3 6.3 10.4 0.16 11.3 2.2 1.9 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal DUF3643 PF12356.3 EXF86479.1 - 0.074 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3643) Pyridox_oxase_2 PF12766.2 EXF86480.1 - 1e-19 70.6 0.0 1.7e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PAH PF02671.16 EXF86483.1 - 0.13 11.8 0.0 0.28 10.8 0.0 1.6 1 0 0 1 1 1 0 Paired amphipathic helix repeat DUF3368 PF11848.3 EXF86485.1 - 0.1 12.1 0.0 0.66 9.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3368) Fungal_trans PF04082.13 EXF86486.1 - 6.9e-43 146.3 0.0 1e-42 145.8 0.0 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF86486.1 - 2.7e-08 33.6 6.7 5.7e-08 32.5 4.7 1.5 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Ank_2 PF12796.2 EXF86487.1 - 4.6e-10 39.7 0.0 1.8e-09 37.8 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EXF86487.1 - 2.1e-07 30.3 0.1 0.01 15.6 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeat NACHT PF05729.7 EXF86487.1 - 3.6e-07 29.9 0.0 1.5e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 NACHT domain Ank_4 PF13637.1 EXF86487.1 - 8.1e-07 29.3 0.0 0.00014 22.2 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) AAA_16 PF13191.1 EXF86487.1 - 0.0002 21.3 0.1 0.0033 17.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain Ank_3 PF13606.1 EXF86487.1 - 0.00088 19.2 0.0 2.8 8.4 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat AAA_22 PF13401.1 EXF86487.1 - 0.0056 16.8 0.0 0.048 13.7 0.0 2.5 2 1 1 3 3 3 1 AAA domain Ank_5 PF13857.1 EXF86487.1 - 0.0056 16.8 0.0 4 7.8 0.0 2.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) DUF2075 PF09848.4 EXF86487.1 - 0.0067 15.4 0.0 0.012 14.5 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 EXF86487.1 - 0.058 14.2 0.1 0.4 11.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.17 EXF86487.1 - 0.067 13.3 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_19 PF13245.1 EXF86487.1 - 0.16 11.7 0.5 1.9 8.2 0.0 2.9 3 0 0 3 3 2 0 Part of AAA domain Peroxin-3 PF04882.7 EXF86487.1 - 0.18 10.4 1.3 4.5 5.8 0.1 2.4 1 1 0 2 2 2 0 Peroxin-3 zf-RING_2 PF13639.1 EXF86488.1 - 1.7e-16 59.7 16.1 5.1e-16 58.2 4.8 2.3 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.1 EXF86488.1 - 3.9e-13 48.8 8.5 4e-10 39.2 1.8 2.2 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EXF86488.1 - 8.6e-09 34.9 14.5 1e-06 28.2 4.1 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EXF86488.1 - 2.4e-08 33.9 3.4 2.4e-08 33.9 2.3 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EXF86488.1 - 2.6e-08 33.7 14.6 4.9e-08 32.8 4.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EXF86488.1 - 3.2e-07 29.9 4.2 3.2e-07 29.9 2.9 2.3 2 0 0 2 2 2 1 zinc-RING finger domain HypA PF01155.14 EXF86488.1 - 0.00066 19.3 0.5 0.00066 19.3 0.3 1.9 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family Prok-RING_4 PF14447.1 EXF86488.1 - 0.0011 18.4 4.2 0.0028 17.1 2.9 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 EXF86488.1 - 0.0021 17.8 3.2 0.0021 17.8 2.2 2.1 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 EXF86488.1 - 0.037 13.7 12.1 1.8 8.3 0.2 2.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_UBOX PF13445.1 EXF86488.1 - 0.071 12.8 4.0 0.27 10.9 0.1 3.3 2 1 1 3 3 3 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EXF86488.1 - 0.16 11.8 13.7 0.54 10.1 1.3 2.9 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING zf-RING_3 PF14369.1 EXF86488.1 - 0.2 11.6 8.7 0.49 10.4 3.8 2.5 2 0 0 2 2 2 0 zinc-finger Rad50_zn_hook PF04423.9 EXF86488.1 - 0.25 10.8 1.6 1.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif DZR PF12773.2 EXF86488.1 - 0.31 10.9 3.9 2.5 7.9 0.3 2.5 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.1 EXF86488.1 - 0.81 9.3 15.3 0.36 10.4 3.5 2.3 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PHD PF00628.24 EXF86488.1 - 3.5 7.4 15.2 5.2 6.8 4.3 2.5 2 0 0 2 2 2 0 PHD-finger Menin PF05053.8 EXF86488.1 - 4.4 5.3 9.1 0.057 11.5 0.8 1.8 3 0 0 3 3 3 0 Menin zinc-ribbons_6 PF07191.7 EXF86488.1 - 6.6 6.5 8.2 2.3 8.0 0.3 2.7 2 1 0 3 3 3 0 zinc-ribbons Baculo_RING PF05883.6 EXF86488.1 - 8.5 6.2 8.0 0.25 11.1 1.2 1.6 2 0 0 2 2 1 0 Baculovirus U-box/Ring-like domain zf-RING_6 PF14835.1 EXF86488.1 - 8.5 6.2 7.0 4.3 7.2 1.1 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Fis1_TPR_C PF14853.1 EXF86489.1 - 2e-25 88.3 1.0 4.2e-25 87.3 0.7 1.5 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.1 EXF86489.1 - 2.3e-17 62.0 0.0 4.6e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_2 PF07719.12 EXF86489.1 - 0.0049 16.6 1.4 0.0091 15.8 1.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EXF86489.1 - 0.026 15.1 0.2 0.049 14.3 0.1 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Spc24 PF08286.6 EXF86490.1 - 9e-39 131.8 2.5 5.8e-37 125.9 0.0 2.1 2 0 0 2 2 2 1 Spc24 subunit of Ndc80 IncA PF04156.9 EXF86490.1 - 0.016 14.8 6.7 0.025 14.1 4.7 1.3 1 0 0 1 1 1 0 IncA protein Reo_sigmaC PF04582.7 EXF86490.1 - 0.025 13.7 2.8 0.03 13.5 1.9 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Retrotrans_gag PF03732.12 EXF86490.1 - 0.077 13.0 2.2 0.16 12.0 1.5 1.7 1 1 0 1 1 1 0 Retrotransposon gag protein Abi_C PF14355.1 EXF86490.1 - 0.088 12.7 2.6 1.4 8.9 1.3 2.8 2 1 0 2 2 2 0 Abortive infection C-terminus V_ATPase_I PF01496.14 EXF86490.1 - 0.095 10.5 2.5 0.12 10.2 1.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Miff PF05644.6 EXF86490.1 - 0.13 11.9 6.8 0.17 11.4 4.7 1.1 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Mod_r PF07200.8 EXF86490.1 - 0.14 12.0 7.2 0.21 11.5 5.0 1.2 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein APG6 PF04111.7 EXF86490.1 - 0.18 10.8 5.5 0.29 10.1 3.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 EAP30 PF04157.11 EXF86490.1 - 0.22 10.6 11.3 0.27 10.3 3.9 2.1 1 1 1 2 2 2 0 EAP30/Vps36 family Scaffolding_pro PF11418.3 EXF86490.1 - 0.28 11.5 3.5 0.52 10.6 2.5 1.5 1 1 0 1 1 1 0 Phi29 scaffolding protein Nsp1_C PF05064.8 EXF86490.1 - 0.36 10.4 4.7 0.82 9.3 0.4 2.3 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF948 PF06103.6 EXF86490.1 - 0.38 10.6 2.4 0.75 9.6 0.8 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.7 EXF86490.1 - 0.43 10.3 7.9 0.58 9.9 3.7 2.0 1 1 1 2 2 2 0 Laminin Domain II DUF724 PF05266.9 EXF86490.1 - 0.49 10.0 4.8 0.8 9.3 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Troponin PF00992.15 EXF86490.1 - 0.55 10.2 7.5 0.79 9.7 5.2 1.3 1 0 0 1 1 1 0 Troponin Viral_P18 PF04521.8 EXF86490.1 - 0.63 9.4 8.5 0.22 10.9 1.8 2.2 1 1 1 2 2 2 0 ssRNA positive strand viral 18kD cysteine rich protein HAUS-augmin3 PF14932.1 EXF86490.1 - 0.63 9.1 9.2 0.88 8.6 6.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF2992 PF11208.3 EXF86490.1 - 0.72 9.7 3.4 1.2 9.0 2.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF4164 PF13747.1 EXF86490.1 - 0.73 10.0 15.7 0.35 11.0 6.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) GvpG PF05120.7 EXF86490.1 - 1 9.2 7.5 0.086 12.6 1.4 2.0 2 1 0 2 2 2 0 Gas vesicle protein G DUF2203 PF09969.4 EXF86490.1 - 1 9.5 3.4 1.9 8.7 2.3 1.6 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) XhlA PF10779.4 EXF86490.1 - 2.9 7.8 8.8 8.5 6.3 0.8 2.4 2 0 0 2 2 2 0 Haemolysin XhlA Prefoldin_2 PF01920.15 EXF86490.1 - 3.3 7.5 7.1 8 6.2 0.9 2.3 2 0 0 2 2 2 0 Prefoldin subunit DASH_Dam1 PF08653.5 EXF86490.1 - 6.9 6.5 6.0 45 3.9 0.0 3.4 4 0 0 4 4 3 0 DASH complex subunit Dam1 TPR_MLP1_2 PF07926.7 EXF86490.1 - 7.4 6.3 14.3 14 5.4 9.9 1.4 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein FlxA PF14282.1 EXF86490.1 - 7.9 6.4 13.5 11 6.0 3.3 2.4 1 1 1 2 2 2 0 FlxA-like protein BTB PF00651.26 EXF86492.1 - 3.2e-05 23.8 0.0 8.8e-05 22.4 0.0 1.8 1 1 0 1 1 1 1 BTB/POZ domain Cyclin PF08613.6 EXF86493.1 - 2.4e-36 125.3 0.0 3.6e-36 124.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin TPP_enzyme_N PF02776.13 EXF86494.1 - 6.3e-40 136.4 0.0 3.7e-38 130.6 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EXF86494.1 - 2.2e-24 85.7 0.0 5e-24 84.6 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EXF86494.1 - 2.6e-21 75.7 0.0 7e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DUF4267 PF14087.1 EXF86496.1 - 4.4e-18 64.9 2.5 5.3e-18 64.6 1.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4267) Peptidase_S8 PF00082.17 EXF86497.1 - 1.2e-43 149.3 0.0 2.2e-43 148.4 0.0 1.5 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EXF86497.1 - 2.7e-07 30.9 0.6 8.9e-07 29.3 0.0 2.1 2 0 0 2 2 2 1 Fn3-like domain (DUF1034) MutL PF13941.1 EXF86497.1 - 0.079 11.2 0.4 0.11 10.7 0.3 1.1 1 0 0 1 1 1 0 MutL protein G5 PF07501.7 EXF86497.1 - 0.11 12.4 0.0 0.31 11.0 0.0 1.7 1 0 0 1 1 1 0 G5 domain zf-RING_2 PF13639.1 EXF86498.1 - 3.6e-08 33.0 6.8 3.6e-08 33.0 4.7 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EXF86498.1 - 2.9e-07 30.3 6.3 1.8e-06 27.8 3.4 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EXF86498.1 - 8.3e-07 28.6 2.5 1.6e-06 27.7 0.2 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.1 EXF86498.1 - 2e-05 24.2 5.6 2e-05 24.2 3.9 2.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EXF86498.1 - 0.00043 19.8 6.2 0.00043 19.8 4.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) GAGA PF09237.6 EXF86498.1 - 0.12 11.9 2.2 1.4 8.6 0.1 2.6 2 0 0 2 2 2 0 GAGA factor Glyco_hydro_28 PF00295.12 EXF86499.1 - 2.7e-41 141.6 3.9 4.5e-41 140.8 2.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 28 Herpes_gE PF02480.11 EXF86500.1 - 0.032 12.5 0.0 0.061 11.5 0.0 1.4 1 1 1 2 2 2 0 Alphaherpesvirus glycoprotein E zf-RING_5 PF14634.1 EXF86502.1 - 2.7e-06 26.9 5.9 2.7e-06 26.9 4.1 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EXF86502.1 - 1.2e-05 24.9 4.4 2.5e-05 23.8 3.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EXF86502.1 - 2.2e-05 24.1 5.4 2.2e-05 24.1 3.7 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EXF86502.1 - 0.00017 21.5 7.7 0.00017 21.5 5.4 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EXF86502.1 - 0.00035 20.1 7.1 0.00035 20.1 4.9 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EXF86502.1 - 0.0024 17.6 2.9 0.0024 17.6 2.0 2.6 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING FYVE PF01363.16 EXF86502.1 - 1.8 8.5 9.6 4.1 7.3 6.7 1.7 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_4 PF14570.1 EXF86502.1 - 4.8 6.8 8.7 57 3.4 6.2 2.4 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain GATase PF00117.23 EXF86503.1 - 2.2e-05 24.0 0.0 3.1e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I ADH_N PF08240.7 EXF86505.1 - 1.4e-17 63.4 0.8 1.4e-17 63.4 0.6 2.8 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF86505.1 - 1.2e-16 60.4 0.2 2.6e-16 59.3 0.2 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF86505.1 - 2.8e-08 34.7 0.3 4.3e-07 30.8 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_2 PF03446.10 EXF86505.1 - 0.00068 19.5 0.2 0.001 18.9 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Methyltransf_31 PF13847.1 EXF86505.1 - 0.17 11.4 0.1 0.54 9.8 0.1 1.7 1 1 1 2 2 2 0 Methyltransferase domain ADC PF06314.6 EXF86506.1 - 7.4e-35 120.4 0.0 8.7e-35 120.1 0.0 1.0 1 0 0 1 1 1 1 Acetoacetate decarboxylase (ADC) DUF3995 PF13160.1 EXF86507.1 - 0.17 11.9 3.2 0.2 11.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3995) Tyrosinase PF00264.15 EXF86508.1 - 3e-50 171.4 0.0 4.1e-50 171.0 0.0 1.2 1 0 0 1 1 1 1 Common central domain of tyrosinase Na_Ca_ex PF01699.19 EXF86509.1 - 3e-16 59.2 13.3 1.2e-14 54.1 3.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF389 PF04087.9 EXF86509.1 - 0.057 13.3 6.4 0.24 11.3 2.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF389) DUF3112 PF11309.3 EXF86509.1 - 0.12 12.1 0.1 0.12 12.1 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3112) EHN PF06441.7 EXF86511.1 - 6.9e-24 83.9 0.3 1.1e-23 83.2 0.2 1.3 1 0 0 1 1 1 1 Epoxide hydrolase N terminus Abhydrolase_6 PF12697.2 EXF86511.1 - 9.5e-13 48.5 0.5 2.2e-12 47.3 0.0 1.8 2 1 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF86511.1 - 0.025 14.3 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family C2 PF00168.25 EXF86512.1 - 2.1e-14 53.1 0.1 3.8e-11 42.6 0.1 2.4 2 0 0 2 2 2 2 C2 domain DUF2404 PF10296.4 EXF86512.1 - 0.023 14.8 0.0 0.055 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative integral membrane protein conserved region (DUF2404) HET PF06985.6 EXF86513.1 - 4.8e-32 111.0 0.9 8.1e-32 110.2 0.6 1.4 1 0 0 1 1 1 1 Heterokaryon incompatibility protein (HET) p450 PF00067.17 EXF86514.1 - 2.4e-48 164.8 0.0 3.3e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 BolA PF01722.13 EXF86515.1 - 2.9e-16 59.1 0.0 4.6e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 BolA-like protein BOF PF04076.8 EXF86515.1 - 0.038 13.8 0.0 0.052 13.3 0.0 1.2 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein COesterase PF00135.23 EXF86516.1 - 8.3e-97 325.1 0.0 1.1e-96 324.6 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EXF86516.1 - 2.3e-05 24.0 0.1 7.3e-05 22.4 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S8 PF00082.17 EXF86517.1 - 4.2e-43 147.5 0.0 1e-42 146.2 0.0 1.6 1 1 0 1 1 1 1 Subtilase family DUF1034 PF06280.7 EXF86517.1 - 3.2e-16 59.7 0.0 8.1e-16 58.4 0.0 1.7 1 0 0 1 1 1 1 Fn3-like domain (DUF1034) PA PF02225.17 EXF86517.1 - 3.6e-12 45.8 0.0 1e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 PA domain FlgD_ig PF13860.1 EXF86517.1 - 0.0012 18.5 0.0 0.0053 16.4 0.0 2.1 1 0 0 1 1 1 1 FlgD Ig-like domain MFS_1 PF07690.11 EXF86518.1 - 1.2e-28 99.8 74.7 3.9e-27 94.8 31.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1593 PF07632.6 EXF86519.1 - 1.2e-80 270.6 0.0 1.5e-80 270.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1593) REJ PF02010.10 EXF86519.1 - 0.04 12.2 0.0 0.064 11.5 0.0 1.2 1 0 0 1 1 1 0 REJ domain Tyr-DNA_phospho PF06087.7 EXF86520.1 - 6e-66 222.8 0.0 3.6e-65 220.3 0.0 2.1 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EXF86520.1 - 3e-05 23.7 0.0 0.0019 17.9 0.0 2.4 2 0 0 2 2 2 1 PLD-like domain UIM PF02809.15 EXF86520.1 - 0.00037 19.8 0.8 0.0012 18.2 0.6 1.9 1 0 0 1 1 1 1 Ubiquitin interaction motif FAM110_C PF14160.1 EXF86520.1 - 1.2 10.0 4.7 13 6.8 0.0 3.7 4 0 0 4 4 4 0 Centrosome-associated C terminus PNRC PF15365.1 EXF86521.1 - 8.2e-07 28.9 12.3 0.0003 20.7 7.8 3.3 2 0 0 2 2 2 2 Proline-rich nuclear receptor coactivator zf-rbx1 PF12678.2 EXF86522.1 - 3.9e-35 119.7 13.5 4.9e-35 119.4 9.4 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EXF86522.1 - 3.9e-17 61.8 9.8 5.1e-17 61.5 6.8 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EXF86522.1 - 4.7e-07 29.5 11.8 3.1e-06 26.9 8.2 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EXF86522.1 - 0.0013 18.3 11.5 0.023 14.3 8.0 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EXF86522.1 - 0.0035 16.9 9.8 0.39 10.4 6.9 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EXF86522.1 - 0.047 13.7 12.5 0.052 13.5 5.4 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EXF86522.1 - 0.45 10.2 11.6 4.3 7.1 8.0 2.4 1 1 1 2 2 2 0 zinc-RING finger domain zf-HC5HC2H_2 PF13832.1 EXF86522.1 - 0.59 10.1 9.4 1.9 8.4 6.5 1.8 1 1 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.3 EXF86522.1 - 0.87 9.5 9.4 4.8 7.2 6.6 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H PF13771.1 EXF86522.1 - 1.3 9.1 10.6 1.1e+02 3.0 7.4 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_UBOX PF13445.1 EXF86522.1 - 1.8 8.3 7.0 4 7.2 2.4 2.2 1 1 1 2 2 2 0 RING-type zinc-finger SPC12 PF06645.8 EXF86523.1 - 1.7e-28 98.2 0.0 2e-28 97.9 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF2273 PF10031.4 EXF86523.1 - 9.6 5.9 10.3 4.3 7.0 0.4 2.9 3 0 0 3 3 3 0 Small integral membrane protein (DUF2273) CorA PF01544.13 EXF86524.1 - 4.7e-43 147.3 0.0 6.2e-43 146.8 0.0 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein zf-Tim10_DDP PF02953.10 EXF86525.1 - 7.8e-23 79.5 1.1 1e-22 79.1 0.8 1.2 1 0 0 1 1 1 1 Tim10/DDP family zinc finger Toxin_1 PF00087.16 EXF86525.1 - 0.07 13.5 0.2 0.11 12.9 0.2 1.3 1 0 0 1 1 1 0 Snake toxin Ribosomal_L23eN PF03939.8 EXF86526.1 - 6.3e-18 64.5 8.5 6.3e-18 64.5 5.9 2.1 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EXF86526.1 - 1.4e-16 60.1 1.6 2.7e-16 59.2 1.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 DUF3321 PF11968.3 EXF86527.1 - 3.5e-85 285.0 0.0 4.5e-85 284.7 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase (DUF3321) Methyltransf_23 PF13489.1 EXF86527.1 - 0.0029 17.3 0.0 0.007 16.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain HAD_2 PF13419.1 EXF86528.1 - 7.2e-27 94.7 0.0 9.5e-27 94.3 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EXF86528.1 - 0.0087 16.4 0.0 0.01 16.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EXF86528.1 - 0.13 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.20 EXF86529.1 - 6.5e-61 205.7 0.0 1.9e-59 200.9 0.0 2.5 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EXF86529.1 - 5.8e-35 120.5 0.0 2.1e-34 118.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EXF86529.1 - 3.9e-13 49.0 0.0 3.9e-11 42.4 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.9 EXF86529.1 - 0.029 13.4 0.0 0.057 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L7Ae PF01248.21 EXF86529.1 - 0.22 11.0 0.0 0.41 10.1 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family YadA_head PF05658.9 EXF86529.1 - 0.39 11.0 2.7 0.79 10.0 1.9 1.4 1 0 0 1 1 1 0 Head domain of trimeric autotransporter adhesin Aa_trans PF01490.13 EXF86530.1 - 2.6e-58 197.4 32.3 3.3e-58 197.1 22.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Prominin PF05478.6 EXF86530.1 - 0.67 7.4 4.2 1.3 6.4 2.9 1.4 1 0 0 1 1 1 0 Prominin SBDS PF01172.13 EXF86531.1 - 3.3e-24 84.4 0.6 3.7e-24 84.3 0.4 1.1 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein CorA PF01544.13 EXF86531.1 - 0.14 11.1 0.0 0.17 10.8 0.0 1.0 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein RhoGEF PF00621.15 EXF86532.1 - 3.8e-27 95.3 0.0 5.9e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 RhoGEF domain E1-E2_ATPase PF00122.15 EXF86533.1 - 1.4e-64 217.2 8.0 7.7e-64 214.8 4.0 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EXF86533.1 - 2.4e-45 154.3 4.3 2.4e-45 154.3 3.0 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EXF86533.1 - 6.5e-34 118.2 0.0 2.3e-32 113.1 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EXF86533.1 - 1.7e-22 79.1 0.0 4.3e-22 77.8 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EXF86533.1 - 2.1e-19 68.7 0.0 4.6e-19 67.6 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EXF86533.1 - 1.8e-16 60.9 0.0 6.9e-16 58.9 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EXF86533.1 - 6.2e-08 32.5 1.3 3.8e-06 26.6 0.6 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EXF86533.1 - 0.0019 18.4 0.0 0.011 15.9 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Proteasome PF00227.21 EXF86534.1 - 1.6e-36 125.3 0.0 1.8e-36 125.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit TUG-UBL1 PF11470.3 EXF86535.1 - 4.3e-24 84.2 0.1 8.7e-24 83.2 0.0 1.6 1 0 0 1 1 1 1 GLUT4 regulating protein TUG UBX PF00789.15 EXF86535.1 - 0.00011 22.1 0.0 0.00071 19.5 0.0 2.2 2 0 0 2 2 2 1 UBX domain DUF4294 PF14127.1 EXF86535.1 - 0.01 15.4 0.0 0.026 14.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4294) SspB PF04386.8 EXF86535.1 - 0.019 14.5 0.8 2.9 7.5 0.7 2.7 2 0 0 2 2 2 0 Stringent starvation protein B RBD PF02196.10 EXF86535.1 - 0.02 14.6 0.1 0.042 13.6 0.1 1.5 1 0 0 1 1 1 0 Raf-like Ras-binding domain RA PF00788.18 EXF86535.1 - 0.025 15.0 0.6 0.062 13.7 0.2 1.9 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain Ribosomal_L36e PF01158.13 EXF86536.1 - 8e-40 134.7 6.2 9.1e-40 134.6 4.3 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e LemA PF04011.7 EXF86536.1 - 0.03 13.4 0.1 0.034 13.2 0.1 1.0 1 0 0 1 1 1 0 LemA family Lipase_3 PF01764.20 EXF86538.1 - 1e-32 112.6 0.0 1.4e-32 112.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EXF86538.1 - 0.00035 20.3 0.0 0.00052 19.7 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EXF86538.1 - 0.00052 19.9 0.0 0.0007 19.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.15 EXF86538.1 - 0.00086 19.6 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain DUF2974 PF11187.3 EXF86538.1 - 0.011 15.0 0.0 0.14 11.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) PGAP1 PF07819.8 EXF86538.1 - 0.031 13.8 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Cutinase PF01083.17 EXF86538.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Cutinase Abhydrolase_1 PF00561.15 EXF86538.1 - 0.14 11.7 0.0 0.27 10.7 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold 14-3-3 PF00244.15 EXF86539.1 - 2.2e-113 377.1 0.2 2.7e-113 376.8 0.1 1.1 1 0 0 1 1 1 1 14-3-3 protein Ribosomal_60s PF00428.14 EXF86539.1 - 0.013 15.8 8.0 0.022 15.1 3.1 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein TPR_12 PF13424.1 EXF86539.1 - 0.036 14.0 1.6 1.2 9.0 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Syja_N PF02383.13 EXF86541.1 - 1.8e-84 283.2 0.0 3e-84 282.5 0.0 1.3 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.18 EXF86541.1 - 3.9e-24 85.9 0.1 7.3e-24 85.0 0.1 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Suf PF05843.9 EXF86543.1 - 0.00018 21.3 8.0 0.23 11.1 0.0 3.8 3 1 0 3 3 3 3 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EXF86543.1 - 0.06 13.9 5.8 24 5.9 0.0 6.5 7 2 2 9 9 9 0 Tetratricopeptide repeat peroxidase PF00141.18 EXF86544.1 - 7.5e-49 166.2 0.0 1.2e-48 165.5 0.0 1.3 1 0 0 1 1 1 1 Peroxidase ATP11 PF06644.6 EXF86545.1 - 1.4e-89 300.1 0.5 1.6e-89 299.9 0.3 1.0 1 0 0 1 1 1 1 ATP11 protein Z1 PF10593.4 EXF86545.1 - 0.029 13.5 0.2 0.051 12.7 0.1 1.3 1 0 0 1 1 1 0 Z1 domain AAA PF00004.24 EXF86546.1 - 5.9e-49 165.6 0.0 5e-43 146.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EXF86546.1 - 2.4e-05 25.1 0.0 0.00044 21.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EXF86546.1 - 5.7e-05 22.6 0.0 0.00038 19.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EXF86546.1 - 0.0002 21.4 0.1 0.0037 17.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EXF86546.1 - 0.00024 20.2 0.0 0.00066 18.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus Parvo_NS1 PF01057.12 EXF86546.1 - 0.00066 18.6 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 IstB_IS21 PF01695.12 EXF86546.1 - 0.001 18.5 0.0 0.0024 17.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_16 PF13191.1 EXF86546.1 - 0.0016 18.4 1.9 0.022 14.7 0.0 3.1 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.9 EXF86546.1 - 0.0031 17.4 0.0 0.0075 16.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_19 PF13245.1 EXF86546.1 - 0.0046 16.6 0.0 0.017 14.8 0.0 2.0 1 0 0 1 1 1 1 Part of AAA domain TIP49 PF06068.8 EXF86546.1 - 0.0097 14.6 0.0 0.016 13.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus RNA_helicase PF00910.17 EXF86546.1 - 0.012 15.8 0.0 0.033 14.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_5 PF07728.9 EXF86546.1 - 0.021 14.5 0.0 0.068 12.8 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EXF86546.1 - 0.029 13.5 1.4 0.046 12.8 0.0 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI KaiC PF06745.8 EXF86546.1 - 0.034 13.2 0.0 0.072 12.1 0.0 1.4 1 0 0 1 1 1 0 KaiC PhoH PF02562.11 EXF86546.1 - 0.039 13.1 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_14 PF13173.1 EXF86546.1 - 0.045 13.6 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EXF86546.1 - 0.059 13.3 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EXF86546.1 - 0.071 12.9 0.0 0.24 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EXF86546.1 - 0.075 13.3 0.0 0.17 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EXF86546.1 - 0.09 12.2 0.0 1.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain PPV_E1_C PF00519.12 EXF86546.1 - 0.31 9.5 0.0 0.49 8.9 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase AAA_24 PF13479.1 EXF86546.1 - 1 8.8 4.4 0.29 10.6 0.1 2.0 2 0 0 2 2 2 0 AAA domain Abhydro_lipase PF04083.11 EXF86547.1 - 9.6e-19 66.5 0.0 2e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EXF86547.1 - 4.3e-07 30.0 0.0 7.8e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EXF86547.1 - 0.00017 21.3 0.0 0.00041 20.1 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family SH3BGR PF04908.10 EXF86548.1 - 0.00041 20.2 0.4 0.0025 17.7 0.0 2.6 2 1 1 3 3 3 1 SH3-binding, glutamic acid-rich protein DUF1669 PF07894.7 EXF86549.1 - 3.1 6.9 4.8 4.2 6.4 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) DUF566 PF04484.7 EXF86549.1 - 5.2 6.4 14.8 6.3 6.2 10.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF566) Presenilin PF01080.12 EXF86549.1 - 6.9 5.3 7.8 8.2 5.1 5.4 1.1 1 0 0 1 1 1 0 Presenilin DSPn PF14671.1 EXF86550.1 - 2.5e-43 147.4 0.0 1.4e-40 138.5 0.0 3.1 3 0 0 3 3 3 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.15 EXF86550.1 - 2.3e-15 56.3 0.0 5.8e-15 55.0 0.0 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EXF86550.1 - 1.1e-06 28.2 0.0 2.4e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Pacs-1 PF10254.4 EXF86550.1 - 0.16 10.5 1.3 0.25 9.9 0.9 1.4 1 0 0 1 1 1 0 PACS-1 cytosolic sorting protein Y_phosphatase3 PF13350.1 EXF86550.1 - 0.19 11.9 2.4 0.31 11.2 0.1 2.2 2 0 0 2 2 2 0 Tyrosine phosphatase family Pcc1 PF09341.5 EXF86551.1 - 4.8e-26 90.5 0.2 6e-26 90.2 0.2 1.1 1 0 0 1 1 1 1 Transcription factor Pcc1 HLH PF00010.21 EXF86552.1 - 1.5e-17 63.0 1.5 3.9e-17 61.6 1.0 1.8 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Velvet PF11754.3 EXF86553.1 - 1.9e-73 246.4 0.0 2.3e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 Velvet factor RhoGEF PF00621.15 EXF86554.1 - 4.2e-33 114.7 0.0 1.1e-32 113.3 0.0 1.7 1 0 0 1 1 1 1 RhoGEF domain BAR PF03114.13 EXF86554.1 - 6.8e-12 45.3 0.4 1.8e-11 43.9 0.3 1.7 1 0 0 1 1 1 1 BAR domain Seryl_tRNA_N PF02403.17 EXF86554.1 - 0.38 10.7 4.5 11 6.1 0.3 2.6 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Telomerase_RBD PF12009.3 EXF86555.1 - 1.7e-40 138.1 0.0 3.6e-40 137.0 0.0 1.6 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.22 EXF86555.1 - 3.4e-13 49.4 0.0 2.6e-12 46.5 0.0 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MBOAT_2 PF13813.1 EXF86556.1 - 4.5e-15 55.4 7.8 7.1e-15 54.8 3.9 2.3 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family PAXIP1_C PF15364.1 EXF86558.1 - 0.002 18.0 1.8 0.002 18.0 1.2 2.5 3 0 0 3 3 3 1 PAXIP1-associated-protein-1 C term PTIP binding protein zf-B_box PF00643.19 EXF86558.1 - 0.22 11.4 6.4 0.37 10.7 4.5 1.4 1 0 0 1 1 1 0 B-box zinc finger Myb_DNA-bind_6 PF13921.1 EXF86559.1 - 0.00039 20.4 0.3 0.00067 19.7 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EXF86559.1 - 0.26 11.3 2.7 0.23 11.5 0.4 2.1 2 1 0 2 2 2 0 Myb-like DNA-binding domain WW PF00397.21 EXF86560.1 - 2.3e-08 33.7 3.7 4.4e-08 32.8 2.6 1.5 1 0 0 1 1 1 1 WW domain DUF2076 PF09849.4 EXF86560.1 - 0.0001 22.4 16.9 0.0001 22.4 11.7 2.4 2 1 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) Gly-zipper_Omp PF13488.1 EXF86560.1 - 0.016 14.8 5.3 0.035 13.7 3.7 1.5 1 0 0 1 1 1 0 Glycine zipper TPR_2 PF07719.12 EXF86560.1 - 2.6 8.1 6.0 6.7 6.8 0.7 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat CYSTM PF12734.2 EXF86561.1 - 3.2e-07 30.3 32.7 3.2e-07 30.3 22.7 4.3 2 1 1 3 3 3 1 Cysteine-rich TM module stress tolerance EF-hand_1 PF00036.27 EXF86562.1 - 5.4e-29 97.2 0.6 1.2e-07 30.5 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EXF86562.1 - 4.2e-27 93.5 1.0 3.5e-11 42.5 0.0 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.1 EXF86562.1 - 4.2e-25 87.6 0.3 1.5e-15 57.0 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EXF86562.1 - 5.9e-20 69.3 0.0 6.6e-07 28.6 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EXF86562.1 - 4.6e-18 63.6 1.0 3.7e-06 26.0 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.1 EXF86562.1 - 1.4e-10 40.9 0.0 8.6e-05 22.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.2 EXF86562.1 - 2.3e-05 24.0 0.8 0.06 13.0 0.0 2.8 2 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EXF86562.1 - 0.0003 20.7 0.0 0.022 14.7 0.0 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region UPF0154 PF03672.8 EXF86562.1 - 0.0032 17.0 0.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EXF86562.1 - 0.015 15.2 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 Ca2+ insensitive EF hand TerB PF05099.8 EXF86562.1 - 0.1 12.3 0.0 4.4 7.0 0.0 2.0 1 1 1 2 2 2 0 Tellurite resistance protein TerB Tenui_NCP PF04876.7 EXF86562.1 - 0.12 11.9 0.0 1.6 8.2 0.0 2.1 2 0 0 2 2 2 0 Tenuivirus major non-capsid protein Peptidase_C14 PF00656.17 EXF86563.1 - 4.1e-69 233.0 0.0 4.9e-69 232.7 0.0 1.1 1 0 0 1 1 1 1 Caspase domain Ndc80_HEC PF03801.8 EXF86563.1 - 0.031 13.7 0.0 0.052 12.9 0.0 1.3 1 0 0 1 1 1 0 HEC/Ndc80p family DUF805 PF05656.9 EXF86565.1 - 0.0027 17.5 0.2 0.0042 16.9 0.1 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF805) DUF4178 PF13785.1 EXF86565.1 - 0.023 14.6 0.1 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4178) RCR PF12273.3 EXF86565.1 - 0.075 13.6 0.0 0.13 12.8 0.0 1.3 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Neur_chan_memb PF02932.11 EXF86565.1 - 0.088 12.6 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region UPF0093 PF03653.8 EXF86565.1 - 0.33 10.9 2.2 0.72 9.7 0.1 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0093) DUF3328 PF11807.3 EXF86565.1 - 0.86 9.2 4.4 0.37 10.4 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) HisG PF01634.13 EXF86566.1 - 8.7e-49 165.2 0.4 5e-47 159.5 0.3 2.2 1 1 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.6 EXF86566.1 - 2e-27 94.9 0.1 6.4e-27 93.3 0.0 1.9 2 0 0 2 2 2 1 HisG, C-terminal domain MFS_2 PF13347.1 EXF86567.1 - 3.2e-13 48.8 14.2 3.2e-13 48.8 9.8 2.6 3 0 0 3 3 3 1 MFS/sugar transport protein PUCC PF03209.10 EXF86567.1 - 2.8e-06 26.2 5.7 5.7e-06 25.3 4.0 1.4 1 0 0 1 1 1 1 PUCC protein PAP2 PF01569.16 EXF86567.1 - 0.013 15.1 4.5 0.057 13.0 1.7 2.8 2 0 0 2 2 2 0 PAP2 superfamily MFS_1_like PF12832.2 EXF86567.1 - 0.21 11.3 5.5 0.5 10.1 0.0 3.8 3 1 0 4 4 4 0 MFS_1 like family Pkr1 PF08636.5 EXF86568.1 - 2.9e-32 110.5 6.6 3.8e-32 110.1 4.6 1.1 1 0 0 1 1 1 1 ER protein Pkr1 SDA1 PF05285.7 EXF86569.1 - 8.6 5.5 14.9 16 4.6 10.3 1.3 1 0 0 1 1 1 0 SDA1 Glyco_hydro_3 PF00933.16 EXF86571.1 - 2.6e-57 194.0 0.0 3.7e-57 193.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EXF86571.1 - 1.4e-42 145.7 0.0 2e-42 145.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EXF86571.1 - 1.5e-06 28.0 0.0 3.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III-like domain ACC_epsilon PF13822.1 EXF86572.1 - 3.1 8.2 6.6 5.1 7.5 4.6 1.3 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit RCC1 PF00415.13 EXF86573.1 - 1.2e-46 156.6 11.0 5.9e-10 39.1 0.2 8.5 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EXF86573.1 - 1.8e-30 103.8 37.4 6.8e-08 31.9 0.7 6.7 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Fungal_trans_2 PF11951.3 EXF86574.1 - 1.1e-29 103.2 1.3 1.3e-29 103.0 0.9 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF86574.1 - 7.3e-06 25.7 8.3 1.2e-05 25.0 5.7 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain MFS_1 PF07690.11 EXF86575.1 - 1.4e-41 142.3 54.2 2.1e-38 131.9 38.4 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily DUF1191 PF06697.7 EXF86575.1 - 0.41 9.4 1.0 3.7 6.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1191) DUF1129 PF06570.6 EXF86575.1 - 0.43 9.8 3.4 0.54 9.5 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF4231 PF14015.1 EXF86575.1 - 6 6.8 10.6 12 5.9 0.4 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) Pec_lyase_C PF00544.14 EXF86576.1 - 2.7e-44 151.0 7.1 3.8e-44 150.5 4.9 1.2 1 0 0 1 1 1 1 Pectate lyase Peptidase_M4_C PF02868.10 EXF86577.1 - 8.6e-46 155.6 0.0 2.4e-45 154.2 0.0 1.7 2 0 0 2 2 2 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_M4 PF01447.13 EXF86577.1 - 7.8e-28 97.4 1.7 1.2e-27 96.9 1.2 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain Peptidase_M13 PF01431.16 EXF86577.1 - 0.00043 19.5 0.1 0.00094 18.4 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M13 Senescence PF06911.7 EXF86577.1 - 0.015 14.9 0.1 0.22 11.1 0.0 2.7 4 0 0 4 4 4 0 Senescence-associated protein Sec63 PF02889.11 EXF86578.1 - 3.8e-09 36.2 0.0 4.5e-09 35.9 0.0 1.0 1 0 0 1 1 1 1 Sec63 Brl domain Sec63 PF02889.11 EXF86579.1 - 5.9e-06 25.7 0.0 6.2e-06 25.6 0.0 1.0 1 0 0 1 1 1 1 Sec63 Brl domain DUF3049 PF11250.3 EXF86579.1 - 0.05 13.3 0.0 0.12 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3049) Nuc_sug_transp PF04142.10 EXF86580.1 - 2.1e-80 269.3 6.1 3.2e-80 268.7 4.2 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.11 EXF86580.1 - 3.8e-10 39.6 23.5 5.2e-05 22.9 7.8 2.3 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EXF86580.1 - 7.2e-09 34.9 10.5 1.8e-07 30.4 1.0 2.3 2 1 0 2 2 2 2 UAA transporter family EamA PF00892.15 EXF86580.1 - 1.5e-06 28.2 21.8 0.00047 20.2 2.1 2.8 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EXF86580.1 - 2.4e-05 24.4 19.8 0.00012 22.2 1.6 2.9 2 1 1 3 3 3 2 Multidrug resistance efflux transporter DUF454 PF04304.8 EXF86580.1 - 8.2 6.5 12.5 0.34 10.9 2.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF454) UPF0546 PF10639.4 EXF86580.1 - 9 6.1 9.0 2.9 7.7 1.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 FAD_binding_4 PF01565.18 EXF86581.1 - 2.4e-24 85.3 0.1 4.4e-24 84.5 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EXF86581.1 - 0.0027 17.5 3.7 0.0031 17.4 0.1 2.8 3 0 0 3 3 3 1 Berberine and berberine like DUF2427 PF10348.4 EXF86582.1 - 0.0011 18.4 0.4 0.0041 16.6 0.3 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF2427) DUF2269 PF10027.4 EXF86582.1 - 1.1 9.0 6.4 1.5e+02 2.0 4.5 2.5 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2269) DUF3425 PF11905.3 EXF86583.1 - 4.5e-10 39.5 4.3 1.4e-09 37.9 0.8 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3425) PAP_central PF04928.12 EXF86583.1 - 0.0042 15.9 0.0 0.0064 15.3 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain DUF1690 PF07956.6 EXF86583.1 - 0.12 12.3 5.0 0.2 11.6 3.5 1.3 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) bZIP_1 PF00170.16 EXF86583.1 - 0.21 11.5 9.2 0.44 10.5 6.4 1.6 1 0 0 1 1 1 0 bZIP transcription factor ABC_tran_2 PF12848.2 EXF86583.1 - 0.43 10.4 5.6 0.75 9.6 3.9 1.3 1 0 0 1 1 1 0 ABC transporter DUF4334 PF14232.1 EXF86584.1 - 4.9e-24 83.7 1.0 1.7e-23 82.0 0.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4334) GXWXG PF14231.1 EXF86584.1 - 2.9e-20 71.6 0.1 5.4e-20 70.7 0.0 1.5 1 0 0 1 1 1 1 GXWXG protein FAD_binding_4 PF01565.18 EXF86584.1 - 2.6e-14 52.8 0.0 4.4e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Ndc80_HEC PF03801.8 EXF86584.1 - 0.14 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 HEC/Ndc80p family adh_short PF00106.20 EXF86585.1 - 9.1e-20 71.2 0.3 1.5e-19 70.5 0.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EXF86585.1 - 2.5e-18 66.7 0.3 3.5e-18 66.2 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EXF86585.1 - 1.7e-07 31.0 0.2 2.5e-07 30.5 0.2 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EXF86585.1 - 0.00018 21.2 0.5 0.0004 20.1 0.3 1.6 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase THF_DHG_CYH_C PF02882.14 EXF86585.1 - 0.015 14.3 0.0 0.04 12.9 0.0 1.7 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DUF3669 PF12417.3 EXF86586.1 - 6.7e-27 93.0 0.1 1.2e-26 92.2 0.1 1.4 1 0 0 1 1 1 1 Zinc finger protein Complex1_LYR PF05347.10 EXF86587.1 - 4e-06 26.5 0.0 1.6e-05 24.5 0.0 2.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EXF86587.1 - 4.1e-05 23.6 0.0 4.1e-05 23.6 0.0 2.5 3 0 0 3 3 3 1 Complex1_LYR-like bZIP_1 PF00170.16 EXF86588.1 - 1.7e-06 27.8 4.8 1.7e-06 27.8 3.3 1.7 2 0 0 2 2 2 1 bZIP transcription factor DUF4185 PF13810.1 EXF86589.1 - 2.1e-11 43.3 0.9 3.2e-11 42.7 0.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4185) Glyco_hydro_43 PF04616.9 EXF86589.1 - 0.00027 20.1 0.2 0.0083 15.2 0.0 2.3 1 1 1 2 2 2 2 Glycosyl hydrolases family 43 IBR PF01485.16 EXF86591.1 - 0.0034 17.2 9.5 0.0034 17.2 6.6 5.5 3 2 1 4 4 4 2 IBR domain VWA_2 PF13519.1 EXF86591.1 - 0.066 13.3 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF2264 PF10022.4 EXF86592.1 - 3.9e-124 413.9 0.6 5e-124 413.6 0.4 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2264) Zn_clus PF00172.13 EXF86593.1 - 4.8e-08 32.7 9.9 8.5e-08 31.9 6.9 1.3 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Fungal_trans_2 PF11951.3 EXF86593.1 - 0.00024 19.8 5.0 0.00052 18.7 3.5 1.6 1 0 0 1 1 1 1 Fungal specific transcription factor domain RTA1 PF04479.8 EXF86594.1 - 2e-57 194.3 4.2 2.7e-57 193.8 2.9 1.1 1 0 0 1 1 1 1 RTA1 like protein DctQ PF04290.7 EXF86594.1 - 0.032 13.9 0.9 0.032 13.9 0.6 2.7 3 1 0 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF3989 PF13150.1 EXF86594.1 - 0.12 11.8 1.2 13 5.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3989) DUF3176 PF11374.3 EXF86595.1 - 9.1e-31 106.0 2.0 2.4e-30 104.6 1.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3176) Peptidase_M36 PF02128.10 EXF86597.1 - 5e-160 532.4 3.7 6.5e-160 532.0 2.6 1.1 1 0 0 1 1 1 1 Fungalysin metallopeptidase (M36) FTP PF07504.8 EXF86597.1 - 3.9e-12 45.4 4.5 7.4e-11 41.3 2.9 2.7 2 0 0 2 2 2 1 Fungalysin/Thermolysin Propeptide Motif Peptidase_M4_C PF02868.10 EXF86597.1 - 0.0081 15.9 0.0 0.017 14.8 0.0 1.6 1 0 0 1 1 1 1 Thermolysin metallopeptidase, alpha-helical domain Peptidase_MA_2 PF13485.1 EXF86597.1 - 0.01 15.8 0.8 0.17 11.9 0.0 2.3 2 0 0 2 2 2 0 Peptidase MA superfamily AMP-binding PF00501.23 EXF86598.1 - 3.7e-249 826.0 0.0 8.2e-86 287.9 0.0 3.4 3 0 0 3 3 3 3 AMP-binding enzyme Condensation PF00668.15 EXF86598.1 - 2.3e-167 555.3 4.6 5e-34 117.5 0.6 6.9 6 1 0 6 6 6 6 Condensation domain PP-binding PF00550.20 EXF86598.1 - 2.7e-59 197.3 15.0 9.4e-11 41.8 0.1 7.1 6 0 0 6 6 6 6 Phosphopantetheine attachment site AMP-binding_C PF13193.1 EXF86598.1 - 3.4e-15 56.7 0.0 3.6e-05 24.6 0.0 4.8 4 0 0 4 4 4 3 AMP-binding enzyme C-terminal domain WES_acyltransf PF03007.11 EXF86598.1 - 1.5e-07 31.2 0.4 0.16 11.4 0.0 5.5 6 0 0 6 6 6 2 Wax ester synthase-like Acyl-CoA acyltransferase domain Transferase PF02458.10 EXF86598.1 - 1.3e-05 23.8 0.1 0.6 8.4 0.0 5.3 6 0 0 6 6 6 2 Transferase family AATase PF07247.7 EXF86598.1 - 0.33 9.4 0.0 64 1.9 0.0 4.0 6 0 0 6 6 6 0 Alcohol acetyltransferase K_oxygenase PF13434.1 EXF86600.1 - 2.9e-107 358.5 0.0 8.8e-107 356.9 0.0 1.6 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_3 PF13738.1 EXF86600.1 - 1.4e-10 41.5 0.0 2.1e-09 37.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EXF86600.1 - 5.4e-10 39.2 0.2 3.6e-07 30.0 0.0 2.6 2 1 0 2 2 2 2 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EXF86600.1 - 0.0001 22.2 0.0 0.00022 21.1 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Glyco_tran_WecB PF03808.8 EXF86600.1 - 0.13 11.6 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Fungal_trans PF04082.13 EXF86601.1 - 1.8e-16 59.8 0.0 3.6e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 Fungal specific transcription factor domain Zn_clus PF00172.13 EXF86601.1 - 1.8e-06 27.7 11.4 3.3e-06 26.9 7.9 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain IF-2B PF01008.12 EXF86602.1 - 2.4e-22 79.2 0.0 3.3e-22 78.8 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family NUDIX PF00293.23 EXF86602.1 - 1.8e-11 43.8 0.1 2.7e-11 43.2 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain Aminotran_5 PF00266.14 EXF86602.1 - 0.11 11.1 0.1 0.19 10.4 0.1 1.3 1 0 0 1 1 1 0 Aminotransferase class-V FliL PF03748.9 EXF86602.1 - 0.13 12.3 0.0 0.69 9.9 0.0 2.1 2 0 0 2 2 2 0 Flagellar basal body-associated protein FliL MFS_1 PF07690.11 EXF86603.1 - 5.3e-30 104.3 22.4 5.3e-30 104.3 15.5 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF2306 PF10067.4 EXF86604.1 - 0.067 13.3 0.3 0.067 13.3 0.2 3.6 3 1 1 4 4 4 0 Predicted membrane protein (DUF2306) DUF2627 PF11118.3 EXF86604.1 - 0.26 11.4 13.1 0.15 12.2 0.7 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2627) DUF1461 PF07314.6 EXF86604.1 - 2.1 8.0 7.0 1.1 9.0 3.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1461) FF PF01846.14 EXF86605.1 - 8e-10 38.5 5.8 4.5e-09 36.1 0.3 3.1 3 0 0 3 3 3 2 FF domain WW PF00397.21 EXF86605.1 - 1.3e-08 34.4 2.9 1.3e-08 34.4 2.0 2.8 3 0 0 3 3 3 1 WW domain PAP2 PF01569.16 EXF86606.1 - 4.3e-23 81.4 1.3 4.3e-23 81.4 0.9 2.2 2 1 0 2 2 2 1 PAP2 superfamily Zip PF02535.17 EXF86606.1 - 0.027 13.4 0.7 0.043 12.8 0.0 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter DUF663 PF04950.7 EXF86607.1 - 1.2e-102 342.8 0.0 1.7e-102 342.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EXF86607.1 - 3e-20 71.5 0.0 7.1e-20 70.3 0.0 1.7 1 0 0 1 1 1 1 AARP2CN (NUC121) domain cobW PF02492.14 EXF86608.1 - 1e-34 119.5 0.0 1.3e-34 119.2 0.0 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ArgK PF03308.11 EXF86608.1 - 8.7e-05 21.4 0.5 0.00078 18.2 0.3 2.0 1 1 0 1 1 1 1 ArgK protein MMR_HSR1 PF01926.18 EXF86608.1 - 0.005 16.7 0.0 0.015 15.2 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.1 EXF86608.1 - 0.0097 16.2 0.0 0.013 15.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EXF86608.1 - 0.023 14.2 0.0 0.033 13.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EXF86608.1 - 0.036 13.4 0.4 0.07 12.5 0.3 1.6 1 1 0 1 1 1 0 AAA domain CbiA PF01656.18 EXF86608.1 - 0.047 13.0 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 EXF86608.1 - 0.072 13.9 0.3 0.15 12.9 0.2 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.12 EXF86608.1 - 0.1 12.0 0.0 0.28 10.5 0.0 1.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.1 EXF86608.1 - 0.15 12.3 0.1 0.38 11.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain TMEM51 PF15345.1 EXF86608.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 AAA_21 PF13304.1 EXF86608.1 - 0.16 11.9 0.0 0.28 11.1 0.0 1.4 2 0 0 2 2 2 0 AAA domain ResIII PF04851.10 EXF86608.1 - 0.16 11.7 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PPI_Ypi1 PF07491.6 EXF86609.1 - 4.2e-24 83.9 1.2 4.2e-24 83.9 0.9 2.1 2 1 0 2 2 2 1 Protein phosphatase inhibitor Zip PF02535.17 EXF86609.1 - 1.9 7.4 7.1 2.2 7.1 4.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.7 EXF86609.1 - 4.3 5.1 7.2 4.7 5.0 5.0 1.0 1 0 0 1 1 1 0 Nop14-like family DUF3827 PF12877.2 EXF86609.1 - 4.5 5.2 6.4 4.7 5.1 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) MMR_HSR1 PF01926.18 EXF86610.1 - 5.1e-05 23.1 0.0 0.00017 21.4 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase L51_S25_CI-B8 PF05047.11 EXF86611.1 - 5.1e-17 61.3 0.1 8e-17 60.7 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain HECT PF00632.20 EXF86612.1 - 6.4e-79 265.3 0.0 8.8e-79 264.9 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) C1_1 PF00130.17 EXF86612.1 - 0.094 12.4 0.4 0.18 11.5 0.3 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3712 PF12505.3 EXF86613.1 - 7.6e-12 45.3 0.0 1.8e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3712) ADH_N PF08240.7 EXF86614.1 - 3.4e-26 91.1 2.0 1e-25 89.5 0.7 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EXF86614.1 - 1.9e-16 59.7 0.0 2.9e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EXF86614.1 - 1.1e-05 26.3 0.0 2e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EXF86614.1 - 0.0034 17.9 0.0 0.0064 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FAD_binding_3 PF01494.14 EXF86614.1 - 0.019 14.0 0.1 0.029 13.4 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain Gp_dh_N PF00044.19 EXF86614.1 - 0.027 14.4 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain fn3 PF00041.16 EXF86614.1 - 0.03 14.4 0.0 5.2 7.2 0.0 2.3 2 0 0 2 2 2 0 Fibronectin type III domain DUF2338 PF10100.4 EXF86614.1 - 0.17 10.2 0.0 0.24 9.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2338) S10_plectin PF03501.10 EXF86615.1 - 1.4e-41 140.2 0.1 1.7e-41 139.9 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain Telomere_Sde2 PF13019.1 EXF86616.1 - 1.7e-68 229.3 0.7 2.5e-68 228.8 0.5 1.2 1 0 0 1 1 1 1 Telomere stability and silencing COX6B PF02297.12 EXF86617.1 - 1.7e-18 66.3 4.5 2e-18 66.1 3.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APOBEC_C PF05240.9 EXF86617.1 - 0.0064 15.8 0.7 0.011 15.1 0.5 1.4 1 0 0 1 1 1 1 APOBEC-like C-terminal domain B12D PF06522.6 EXF86618.1 - 7.2e-10 38.4 0.0 8.8e-10 38.1 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RRM_1 PF00076.17 EXF86619.1 - 4.7e-18 64.5 0.0 6.6e-18 64.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EXF86619.1 - 4.2e-13 49.0 0.0 1.2e-12 47.5 0.0 1.8 2 1 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EXF86619.1 - 3.8e-10 39.4 0.0 7e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EXF86619.1 - 0.091 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EXF86619.1 - 0.093 12.4 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Limkain b1 WD40 PF00400.27 EXF86620.1 - 1.1e-17 63.1 0.7 1.3e-05 24.8 0.0 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat SRA1 PF07304.6 EXF86620.1 - 2.2e-12 46.9 0.0 2.2e-12 46.9 0.0 2.7 2 1 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Sec16_C PF12931.2 EXF86620.1 - 4e-08 33.3 0.2 1.6e-07 31.3 0.2 1.9 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 GET2 PF08690.5 EXF86621.1 - 0.083 12.1 14.5 1.6 7.9 3.5 4.1 3 1 0 3 3 3 0 GET complex subunit GET2 p450 PF00067.17 EXF86622.1 - 1.8e-39 135.6 0.0 2.5e-25 88.9 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 CoA_transf_3 PF02515.12 EXF86622.1 - 0.044 13.0 0.0 0.078 12.2 0.0 1.4 1 0 0 1 1 1 0 CoA-transferase family III HLH PF00010.21 EXF86623.1 - 8.4e-08 31.8 0.0 2e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Peptidase_M16_C PF05193.16 EXF86623.1 - 0.1 12.2 0.4 0.24 11.0 0.3 1.6 1 0 0 1 1 1 0 Peptidase M16 inactive domain DUF4066 PF13278.1 EXF86625.1 - 1.7e-28 98.9 0.0 2.9e-28 98.2 0.0 1.4 1 0 0 1 1 1 1 Putative amidotransferase DJ-1_PfpI PF01965.19 EXF86625.1 - 6.1e-14 51.7 0.0 9.4e-14 51.0 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.23 EXF86625.1 - 0.013 14.9 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Gp_dh_C PF02800.15 EXF86626.1 - 1.7e-74 248.4 0.1 2.6e-74 247.9 0.1 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EXF86626.1 - 4.4e-60 202.0 0.2 7.5e-60 201.2 0.1 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EXF86626.1 - 0.00094 19.0 0.2 0.0042 17.0 0.1 2.2 1 1 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus ADH_zinc_N PF00107.21 EXF86626.1 - 0.0051 16.3 0.5 0.012 15.1 0.1 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EXF86626.1 - 0.1 11.7 0.1 0.36 9.9 0.0 1.8 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Laminin_I PF06008.9 EXF86628.1 - 0.00013 21.3 8.0 0.00013 21.3 5.6 5.3 2 2 2 4 4 4 1 Laminin Domain I AAA_13 PF13166.1 EXF86628.1 - 0.00031 19.3 41.0 0.0027 16.2 6.4 3.4 3 0 0 3 3 3 3 AAA domain CENP-F_leu_zip PF10473.4 EXF86628.1 - 0.00053 19.8 45.6 0.0017 18.2 5.3 6.0 3 2 3 6 6 6 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HALZ PF02183.13 EXF86628.1 - 0.0038 16.9 10.1 3 7.6 0.2 5.2 4 1 1 5 5 5 2 Homeobox associated leucine zipper DUF3235 PF11574.3 EXF86628.1 - 0.16 12.2 0.4 26 5.1 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) EzrA PF06160.7 EXF86628.1 - 0.24 9.5 48.9 0.015 13.4 4.8 4.3 3 2 1 4 4 4 0 Septation ring formation regulator, EzrA Reo_sigmaC PF04582.7 EXF86628.1 - 2.5 7.1 28.0 0.47 9.5 1.2 4.6 2 1 1 5 5 5 0 Reovirus sigma C capsid protein TIP49 PF06068.8 EXF86629.1 - 2.6e-174 579.6 4.6 3e-174 579.4 3.2 1.0 1 0 0 1 1 1 1 TIP49 C-terminus RuvB_N PF05496.7 EXF86629.1 - 2.6e-09 36.4 3.8 2.6e-05 23.4 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 EXF86629.1 - 1.9e-08 34.5 0.7 3.3e-05 24.1 0.0 3.2 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DnaB_C PF03796.10 EXF86629.1 - 2.7e-06 26.4 0.4 4.9e-06 25.6 0.3 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 EXF86629.1 - 0.00017 21.7 0.0 0.17 12.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EXF86629.1 - 0.00036 20.5 0.0 0.0032 17.4 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain Mg_chelatase PF01078.16 EXF86629.1 - 0.00077 18.6 0.6 0.019 14.1 0.2 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EXF86629.1 - 0.0012 18.7 0.0 1.5 8.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 EXF86629.1 - 0.0067 15.9 0.1 2.2 7.7 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_5 PF07728.9 EXF86629.1 - 0.017 14.8 0.2 2.9 7.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EXF86629.1 - 0.025 14.3 0.4 0.094 12.4 0.2 1.9 1 1 0 1 1 1 0 Part of AAA domain Parvo_NS1 PF01057.12 EXF86629.1 - 0.027 13.3 0.0 0.052 12.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.1 EXF86629.1 - 0.036 13.4 0.0 0.073 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EXF86629.1 - 0.051 13.1 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EXF86629.1 - 0.07 13.4 0.0 0.6 10.4 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EXF86629.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain GYF PF02213.11 EXF86630.1 - 8.3e-11 41.3 0.8 1.9e-10 40.1 0.5 1.6 1 0 0 1 1 1 1 GYF domain HTH_WhiA PF02650.9 EXF86630.1 - 0.0077 16.6 0.5 0.018 15.4 0.3 1.5 1 0 0 1 1 1 1 WhiA C-terminal HTH domain Ribosomal_S30 PF04758.9 EXF86630.1 - 1.4 8.6 4.9 5.6 6.7 1.9 2.6 2 0 0 2 2 2 0 Ribosomal protein S30 UFD1 PF03152.9 EXF86631.1 - 1.1e-67 226.6 0.0 1.3e-67 226.3 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 NP1-WLL PF11733.3 EXF86633.1 - 0.09 13.0 4.3 0.39 10.9 2.9 2.1 1 1 1 2 2 2 0 Non-capsid protein NP1 ORC6 PF05460.8 EXF86635.1 - 0.026 13.6 9.3 0.036 13.1 6.4 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) PBP1_TM PF14812.1 EXF86635.1 - 2.1 8.7 4.5 3.9 7.8 3.1 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Serendipity_A PF05482.7 EXF86636.1 - 1.3 7.4 0.7 2 6.7 0.5 1.2 1 0 0 1 1 1 0 Serendipity locus alpha protein (SRY-A) PIG-H PF10181.4 EXF86637.1 - 5.6e-27 93.1 0.1 8.1e-27 92.6 0.0 1.2 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component PseudoU_synth_1 PF01416.15 EXF86638.1 - 1.4e-25 89.6 0.0 3.4e-19 69.2 0.0 2.8 2 1 0 2 2 2 2 tRNA pseudouridine synthase Ras PF00071.17 EXF86639.1 - 1.2e-19 70.2 0.0 1.8e-19 69.7 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EXF86639.1 - 3.7e-08 33.8 0.0 1e-07 32.4 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EXF86639.1 - 0.0072 15.5 0.0 0.49 9.6 0.0 2.1 2 0 0 2 2 2 2 ADP-ribosylation factor family SRPRB PF09439.5 EXF86639.1 - 0.052 12.7 0.1 0.12 11.6 0.0 1.6 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EXF86639.1 - 0.089 12.2 0.1 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_pol_Rpb4 PF03874.11 EXF86640.1 - 1.9e-22 79.4 0.0 2.3e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF3926 PF13080.1 EXF86640.1 - 4.8 6.7 5.4 0.59 9.7 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3926) Pribosyl_synth PF14572.1 EXF86641.1 - 1.1e-43 149.0 0.6 2.6e-43 147.9 0.3 1.7 2 0 0 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran_N PF13793.1 EXF86641.1 - 2.7e-31 107.7 0.0 8.4e-31 106.1 0.0 1.8 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.22 EXF86641.1 - 3.8e-15 55.7 0.7 7.3e-15 54.7 0.0 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EXF86641.1 - 0.00045 19.4 0.1 0.00075 18.7 0.0 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 EXF86641.1 - 0.11 11.7 0.0 0.18 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase Herpes_capsid PF06112.6 EXF86642.1 - 0.64 10.0 7.9 0.99 9.4 5.5 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Med3 PF11593.3 EXF86642.1 - 1.6 7.8 13.4 1.9 7.6 9.3 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal PUF PF00806.14 EXF86643.1 - 4.5e-39 129.7 0.8 2.8e-06 26.5 0.0 8.7 9 0 0 9 9 9 7 Pumilio-family RNA binding repeat ATP-synt_D PF01813.12 EXF86643.1 - 0.041 13.4 0.6 0.071 12.6 0.4 1.3 1 0 0 1 1 1 0 ATP synthase subunit D Auxin_repressed PF05564.7 EXF86643.1 - 1.6 9.3 7.2 0.42 11.2 0.5 2.5 2 0 0 2 2 2 0 Dormancy/auxin associated protein MRP-S33 PF08293.6 EXF86644.1 - 1.7e-28 98.4 0.0 2.1e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 Cupin_4 PF08007.7 EXF86644.1 - 0.078 12.2 0.0 0.48 9.6 0.0 1.8 2 0 0 2 2 2 0 Cupin superfamily protein Ribonuclease_3 PF00636.21 EXF86645.1 - 3.6e-13 49.9 0.0 1.1e-12 48.3 0.0 1.9 2 0 0 2 2 2 1 Ribonuclease III domain Ribonucleas_3_3 PF14622.1 EXF86645.1 - 1.4e-08 34.7 0.0 4.7e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 Ribonuclease-III-like dsrm PF00035.20 EXF86645.1 - 0.00018 22.0 0.2 0.00044 20.7 0.1 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif BCL9 PF11502.3 EXF86645.1 - 0.027 13.9 0.2 0.058 12.9 0.1 1.5 1 0 0 1 1 1 0 B-cell lymphoma 9 protein ACBP PF00887.14 EXF86646.1 - 1e-11 44.3 0.2 2.8e-11 42.9 0.2 1.8 1 0 0 1 1 1 1 Acyl CoA binding protein Molybdopterin PF00384.17 EXF86647.1 - 4.3e-74 249.8 0.0 2e-37 128.9 0.0 2.2 1 1 1 2 2 2 2 Molybdopterin oxidoreductase Fer2_4 PF13510.1 EXF86647.1 - 3.9e-20 71.4 0.2 9.8e-20 70.1 0.2 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.4 EXF86647.1 - 1.5e-18 65.7 0.1 4.6e-18 64.1 0.1 1.9 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region DUF1982 PF09326.6 EXF86647.1 - 6.3e-15 55.0 0.0 1.7e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1982) Fer2 PF00111.22 EXF86647.1 - 8.5e-09 35.0 0.8 8.5e-09 35.0 0.5 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain TPP_enzyme_M PF00205.17 EXF86647.1 - 0.0039 16.9 0.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain Fer4 PF00037.22 EXF86647.1 - 0.11 12.1 1.1 3.1 7.5 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain UPF0061 PF02696.9 EXF86648.1 - 3.6e-121 404.8 0.0 4.6e-121 404.5 0.0 1.0 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Aldo_ket_red PF00248.16 EXF86649.1 - 2.4e-45 154.5 0.0 3.2e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family XRCC4 PF06632.7 EXF86650.1 - 1.1e-11 44.2 7.0 1.8e-11 43.4 4.8 1.3 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 SPX PF03105.14 EXF86650.1 - 0.029 14.1 7.0 0.039 13.7 4.8 1.3 1 0 0 1 1 1 0 SPX domain Nol1_Nop2_Fmu PF01189.12 EXF86652.1 - 1.3e-97 326.6 0.0 4.8e-97 324.7 0.0 1.9 2 0 0 2 2 2 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 EXF86652.1 - 0.0025 17.4 0.0 0.0048 16.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EXF86652.1 - 0.0043 17.0 0.0 0.0093 15.9 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 EXF86652.1 - 0.0054 17.2 0.0 0.015 15.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EXF86652.1 - 0.015 14.8 0.0 0.026 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Blt1 PF12754.2 EXF86653.1 - 1.9e-33 116.3 4.4 1.8e-29 103.3 0.5 2.2 1 1 1 2 2 2 2 Cell-cycle control medial ring component ubiquitin PF00240.18 EXF86653.1 - 3.6e-05 23.0 0.0 5.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Class_IIIsignal PF04021.7 EXF86653.1 - 0.15 11.7 0.3 0.25 11.1 0.2 1.3 1 0 0 1 1 1 0 Class III signal peptide Cpn60_TCP1 PF00118.19 EXF86654.1 - 7.8e-117 390.8 9.2 9.6e-117 390.5 6.4 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cofilin_ADF PF00241.15 EXF86654.1 - 1.8e-34 118.3 1.5 3.6e-34 117.3 1.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF1547 PF07577.6 EXF86654.1 - 0.17 11.5 1.5 0.3 10.8 0.2 2.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1547) Baculo_PEP_C PF04513.7 EXF86657.1 - 0.0035 17.1 5.1 0.0065 16.3 3.5 1.4 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus Tape_meas_lam_C PF09718.5 EXF86657.1 - 0.052 13.4 1.6 0.14 12.1 1.1 1.6 1 0 0 1 1 1 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF908 PF06012.7 EXF86659.1 - 0.12 11.6 0.1 0.12 11.6 0.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Transferase PF02458.10 EXF86660.1 - 4e-20 71.6 0.0 3e-15 55.6 0.0 2.0 2 0 0 2 2 2 2 Transferase family Isochorismatase PF00857.15 EXF86661.1 - 3.4e-19 69.4 0.0 4.4e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family TrbH PF07283.6 EXF86661.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Conjugal transfer protein TrbH Cyclin_N PF00134.18 EXF86662.1 - 5e-39 132.7 0.2 1.2e-38 131.5 0.1 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EXF86662.1 - 1.6e-13 50.6 0.1 4.3e-13 49.2 0.1 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain